variant_id,position_id,protein,dms_id,uniprot,scaled_effect,predicted?,position,aa1,aa2,wt_mut,aa1_polarity,aa2_polarity,aa1_pi,aa2_pi,delta_pi,grantham,aa1_weight,aa2_weight,delta_weight,aa1_volume,aa2_volume,delta_volume,aa1_psic,aa2_psic,delta_psic,local_density,accessibility,dssp_sec_str,phi_psi_reg,delta_solvent_accessibility,b_factor,mut_msa_congruency,mut_mut_msa_congruency,seq_ind_closest_mut,local_biochem,local_conservation,selection_coefficient,evolutionary_coupling_avg,predictions beta-lactamase_0_E195F,beta-lactamase_0_195,TEM-1,beta-lactamase_0,P62593,-0.52352,NO,195,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.186,-4.475,2.289,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.0500837,0.00496565,-0.52352 beta-lactamase_0_Q88W,beta-lactamase_0_88,TEM-1,beta-lactamase_0,P62593,-0.451832,NO,88,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.086,-5.502,3.416,,0.807,,B,0.64,2.03,0.4,,77.62,APH,-1.53433,0.0500837,0.00504167,-0.451832 beta-lactamase_0_S104N,beta-lactamase_0_104,TEM-1,beta-lactamase_0,P62593,-0.409887,NO,104,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.015,-3.421,2.406,,0.04,,b,0.27,0.57,1.148,,63.29,HPO,-1.05267,0.0500837,0.00218083,-0.409887 kka2_1:2_D62Q,kka2_1:2_62,Kka2,kka2_1:2,P00552,-0.382303,NO,62,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.591,-2.887,1.296,,0.262,H,A,0.75,0.08,10.048,10.048,64.39,PAA,-1.77833,0.295029,0.00744243,-0.382303 beta-lactamase_0_A123M,beta-lactamase_0_123,TEM-1,beta-lactamase_0,P62593,-0.368171,NO,123,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.834,-4.443,3.609,,0.039,H,A,0.46,-0.72,1.308,,41.26,PHH,-1.47367,0.0500837,0.0010157,-0.368171 beta-lactamase_0_C121E,beta-lactamase_0_121,TEM-1,beta-lactamase_0,P62593,-0.362017,NO,121,C,E,CE,Special,negativeCharge,5.07,3.22,-1.85,170,121,147,26,108.5,138.4,29.9,-0.953,-3.987,3.034,,,H,A,0.46,-0.81,3.302,,63.29,HOP,-1.46767,0.0500837,0.000744322,-0.362017 beta-lactamase_0_A123Q,beta-lactamase_0_123,TEM-1,beta-lactamase_0,P62593,-0.346038,NO,123,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.834,-3.948,3.114,,0.039,H,A,0.46,-0.72,1.308,,41.26,PHH,-1.47367,0.0500837,0.0010157,-0.346038 beta-lactamase_0_V72K,beta-lactamase_0_72,TEM-1,beta-lactamase_0,P62593,-0.337622,NO,72,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.658,-3.754,2.096,,,H,A,0.44,-1.03,2.964,,65.73,BHH,-1.32167,0.0500837,0.00501194,-0.337622 beta-lactamase_0_V117Q,beta-lactamase_0_117,TEM-1,beta-lactamase_0,P62593,-0.316947,NO,117,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.53,-4.247,2.717,,,H,A,0.44,-0.34,1.16,,65.03,PHB,-1.741,0.0500837,0.00467906,-0.316947 beta-lactamase_0_A123N,beta-lactamase_0_123,TEM-1,beta-lactamase_0,P62593,-0.310783,NO,123,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.834,-3.947,3.113,,0.039,H,A,0.46,-0.72,1.308,,41.26,PHH,-1.47367,0.0500837,0.0010157,-0.310783 kka2_1:1_D62Q,kka2_1:1_62,Kka2,kka2_1:1,P00552,-0.288404,NO,62,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.591,-2.887,1.296,,0.262,H,A,0.75,0.08,10.048,10.048,64.39,PAA,-1.77833,0.520039,0.00744243,-0.288404 kka2_1:1_G164I,kka2_1:1_164,Kka2,kka2_1:1,P00552,-0.261989,NO,164,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.869,-4.238,3.369,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.520039,0.00442091,-0.261989 beta-lactamase_0_C121M,beta-lactamase_0_121,TEM-1,beta-lactamase_0,P62593,-0.255775,NO,121,C,M,CM,Special,Hydrophobic,5.07,5.74,0.67,196,121,149,28,108.5,162.9,54.4,-0.953,-4.506,3.553,,,H,A,0.46,-0.81,3.302,,63.29,HOP,-1.46767,0.0500837,0.000744322,-0.255775 kka2_1:1_A176W,kka2_1:1_176,Kka2,kka2_1:1,P00552,-0.246621,NO,176,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.621,-5.554,3.933,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.520039,0.0083587,-0.246621 beta-lactamase_39_S68E,beta-lactamase_39_68,TEM-1,beta-lactamase_39,P62593,-0.243222,NO,68,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-0.913,-3.241,2.328,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.0495842,0.000800065,-0.243222 beta-lactamase_0_A268K,beta-lactamase_0_268,TEM-1,beta-lactamase_0,P62593,-0.23492,NO,268,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.0500837,0.0102525,-0.23492 Ubiquitin_K48F,Ubiquitin_48,Uba1,Ubiquitin,P0CG48,-0.233871,NO,48,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.436,-4.233,2.797,5.03072,0.132,E,B,2.92,-0.28,1.539,,53.87,OBP,-1.6,0.205827,0.000394633,-0.233871 kka2_1:2_L19H,kka2_1:2_19,Kka2,kka2_1:2,P00552,-0.232793,NO,19,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.254,-3.254,2,,0.08,T,A,0.55,-0.26,17.165,17.165,65.53,BHH,-2.221,0.295029,0.00620703,-0.232793 beta-lactamase_0_V117S,beta-lactamase_0_117,TEM-1,beta-lactamase_0,P62593,-0.224016,NO,117,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.53,-3.729,2.199,,,H,A,0.44,-0.34,1.16,,65.03,PHB,-1.741,0.0500837,0.00467906,-0.224016 beta-lactamase_0_C121K,beta-lactamase_0_121,TEM-1,beta-lactamase_0,P62593,-0.220496,NO,121,C,K,CK,Special,PositiveCharge,5.07,9.74,4.67,202,121,146,25,108.5,168.6,60.1,-0.953,-3.72,2.767,,,H,A,0.46,-0.81,3.302,,63.29,HOP,-1.46767,0.0500837,0.000744322,-0.220496 kka2_1:8_C77N,kka2_1:8_77,Kka2,kka2_1:8,P00552,-0.2161,NO,77,C,N,CN,Special,Polar,5.07,5.47157,0.401575,139,121,132,11,108.5,114.1,5.6,-1.477,-4.016,2.539,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.100394,0.00441216,-0.2161 kka2_1:8_C77N,kka2_1:8_77,Kka2,kka2_1:8,P00552,-0.2161,NO,77,C,N,CN,Special,Polar,5.07,5.47157,0.401575,139,121,132,11,108.5,114.1,5.6,-1.477,-4.016,2.539,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.100394,0.00441216,-0.2161 beta-lactamase_39_K71I,beta-lactamase_39_71,TEM-1,beta-lactamase_39,P62593,-0.206514,NO,71,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-0.8,-4.01,3.21,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.0495842,0.00103192,-0.206514 beta-lactamase_0_V117Y,beta-lactamase_0_117,TEM-1,beta-lactamase_0,P62593,-0.200529,NO,117,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.53,-2.958,1.428,,,H,A,0.44,-0.34,1.16,,65.03,PHB,-1.741,0.0500837,0.00467906,-0.200529 kka2_1:1_G74N,kka2_1:1_74,Kka2,kka2_1:1,P00552,-0.190108,NO,74,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.18,-2.406,1.226,,0.621,T,l,0.75,0.2,15.356,15.356,64.39,POH,-1.91667,0.520039,0.00587035,-0.190108 beta-lactamase_39_S68M,beta-lactamase_39_68,TEM-1,beta-lactamase_39,P62593,-0.181946,NO,68,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-0.913,-4.529,3.616,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.0495842,0.000800065,-0.181946 Ubiquitin_L15N,Ubiquitin_15,Uba1,Ubiquitin,P0CG48,-0.177419,NO,15,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.082,-4.149,3.067,5.14718,0.029,E,B,1.16,-0.53,0.936,,38.69,PHA,-1.40833,0.205827,0.000519738,-0.177419 PSD95pdz3_F325D,PSD95pdz3_325,PSD95pdz3,PSD95pdz3,P31016,-0.171931,NO,325,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.524,-3.6,2.076,5.50654,,,,,12.7236,,,,OHP,-1.314,0.0758425,0.00102273,-0.171931 beta-lactamase_0_A123F,beta-lactamase_0_123,TEM-1,beta-lactamase_0,P62593,-0.171921,NO,123,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.834,-4.065,3.231,,0.039,H,A,0.46,-0.72,1.308,,41.26,PHH,-1.47367,0.0500837,0.0010157,-0.171921 Ubiquitin_K48W,Ubiquitin_48,Uba1,Ubiquitin,P0CG48,-0.169355,NO,48,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.436,-5.386,3.95,5.03072,0.132,E,B,2.92,-0.28,1.539,,53.87,OBP,-1.6,0.205827,0.000394633,-0.169355 kka2_1:8_D220I,kka2_1:8_220,Kka2,kka2_1:8,P00552,-0.16435,NO,220,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.787,-3.808,3.021,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.100394,0.00158066,-0.16435 kka2_1:8_D220I,kka2_1:8_220,Kka2,kka2_1:8,P00552,-0.16435,NO,220,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.787,-3.808,3.021,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.100394,0.00158066,-0.16435 kka2_1:4_G213S,kka2_1:4_213,Kka2,kka2_1:4,P00552,-0.160786,NO,213,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.596,-3.189,2.593,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.168804,0.00187654,-0.160786 kka2_1:4_G213I,kka2_1:4_213,Kka2,kka2_1:4,P00552,-0.157517,NO,213,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.596,-4.264,3.668,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.168804,0.00187654,-0.157517 kka2_1:1_C77N,kka2_1:1_77,Kka2,kka2_1:1,P00552,-0.150846,NO,77,C,N,CN,Special,Polar,5.07,5.47157,0.401575,139,121,132,11,108.5,114.1,5.6,-1.477,-4.016,2.539,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.520039,0.00441216,-0.150846 beta-lactamase_0_A123L,beta-lactamase_0_123,TEM-1,beta-lactamase_0,P62593,-0.146687,NO,123,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.834,-3.096,2.262,,0.039,H,A,0.46,-0.72,1.308,,41.26,PHH,-1.47367,0.0500837,0.0010157,-0.146687 kka2_1:4_C77N,kka2_1:4_77,Kka2,kka2_1:4,P00552,-0.143622,NO,77,C,N,CN,Special,Polar,5.07,5.47157,0.401575,139,121,132,11,108.5,114.1,5.6,-1.477,-4.016,2.539,,0.229,B,b,0.46,-0.57,2.499,,63.26,OOH,-1.55667,0.168804,0.00441216,-0.143622 beta-lactamase_625_L79D,beta-lactamase_625_79,TEM-1,beta-lactamase_625,P62593,-0.143212,NO,79,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.842,-4.141,3.299,,0.007,H,A,0.55,-0.16,0.935,,50.35,HHP,-1.44333,0.213352,0.000947397,-0.143212 beta-lactamase_0_V117N,beta-lactamase_0_117,TEM-1,beta-lactamase_0,P62593,-0.138091,NO,117,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.53,-4.224,2.694,,,H,A,0.44,-0.34,1.16,,65.03,PHB,-1.741,0.0500837,0.00467906,-0.138091 kka2_1:2_C77N,kka2_1:2_77,Kka2,kka2_1:2,P00552,-0.132649,NO,77,C,N,CN,Special,Polar,5.07,5.47157,0.401575,139,121,132,11,108.5,114.1,5.6,-1.477,-4.016,2.539,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.295029,0.00441216,-0.132649 beta-lactamase_39_K71Y,beta-lactamase_39_71,TEM-1,beta-lactamase_39,P62593,-0.132341,NO,71,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-0.8,-4.162,3.362,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.0495842,0.00103192,-0.132341 Ubiquitin_I23W,Ubiquitin_23,Uba1,Ubiquitin,P0CG48,-0.129032,NO,23,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.325,-5.202,3.877,4.67534,,H,A,0.01,-0.93,0.515,,52.12,PHA,-1.54033,0.205827,0.000621252,-0.129032 kka2_1:2_A78W,kka2_1:2_78,Kka2,kka2_1:2,P00552,-0.124879,NO,78,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.744,-5.551,3.807,,0.078,.,B,0.46,-0.53,0.206,,56.06,OHH,-1.863,0.295029,0.00457299,-0.124879 beta-lactamase_0_A123K,beta-lactamase_0_123,TEM-1,beta-lactamase_0,P62593,-0.121107,NO,123,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.834,-3.506,2.672,,0.039,H,A,0.46,-0.72,1.308,,41.26,PHH,-1.47367,0.0500837,0.0010157,-0.121107 kka2_1:1_L19H,kka2_1:1_19,Kka2,kka2_1:1,P00552,-0.1111,NO,19,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.254,-3.254,2,,0.08,T,A,0.55,-0.26,17.165,17.165,65.53,BHH,-2.221,0.520039,0.00620703,-0.1111 beta-lactamase_156_L79K,beta-lactamase_156_79,TEM-1,beta-lactamase_156,P62593,-0.111035,NO,79,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.842,-3.679,2.837,,0.007,H,A,0.55,-0.16,1.831,,50.35,HHP,-1.44333,0.111618,0.000947397,-0.111035 kka2_1:8_A78N,kka2_1:8_78,Kka2,kka2_1:8,P00552,-0.109857,NO,78,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.744,-3.971,2.227,,0.078,,B,1.04,-0.53,1.251,,56.06,OHH,-1.863,0.100394,0.00457299,-0.109857 kka2_1:8_A78N,kka2_1:8_78,Kka2,kka2_1:8,P00552,-0.109857,NO,78,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.744,-3.971,2.227,,0.078,,B,1.04,-0.53,1.251,,56.06,OHH,-1.863,0.100394,0.00457299,-0.109857 kka2_1:8_D101I,kka2_1:8_101,Kka2,kka2_1:8,P00552,-0.108893,NO,101,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.028,-3.84,2.812,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.100394,0.00423361,-0.108893 kka2_1:8_D101I,kka2_1:8_101,Kka2,kka2_1:8,P00552,-0.108893,NO,101,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.028,-3.84,2.812,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.100394,0.00423361,-0.108893 kka2_1:4_D190Q,kka2_1:4_190,Kka2,kka2_1:4,P00552,-0.108452,NO,190,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.708,-3.703,2.995,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.168804,0.00247989,-0.108452 kka2_1:4_A78M,kka2_1:4_78,Kka2,kka2_1:4,P00552,-0.107903,NO,78,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.744,-4.709,2.965,,0.078,.,B,0.46,-0.53,0.594,,56.06,OHH,-1.863,0.168804,0.00457299,-0.107903 beta-lactamase_2500_K71S,beta-lactamase_2500_71,TEM-1,beta-lactamase_2500,P62593,-0.10784,NO,71,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-0.8,-3.161,2.361,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.361275,0.00103192,-0.10784 beta-lactamase_625_V31E,beta-lactamase_625_31,TEM-1,beta-lactamase_625,P62593,-0.104737,NO,31,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.822,-3.908,2.086,,,H,A,0.44,-0.46,2.576,,73.78,BHB,-2.03767,0.213352,0.00478065,-0.104737 beta-lactamase_0_V117K,beta-lactamase_0_117,TEM-1,beta-lactamase_0,P62593,-0.10455,NO,117,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.53,-3.844,2.314,,,H,A,0.44,-0.34,1.16,,65.03,PHB,-1.741,0.0500837,0.00467906,-0.10455 beta-lactamase_0_C121W,beta-lactamase_0_121,TEM-1,beta-lactamase_0,P62593,-0.103866,NO,121,C,W,CW,Special,Hydrophobic,5.07,5.89,0.82,215,121,204,83,108.5,227.8,119.3,-0.953,-5.146,4.193,,,H,A,0.46,-0.81,3.302,,63.29,HOP,-1.46767,0.0500837,0.000744322,-0.103866 beta-lactamase_156_K71Q,beta-lactamase_156_71,TEM-1,beta-lactamase_156,P62593,-0.10346,NO,71,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-0.8,-3.449,2.649,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.111618,0.00103192,-0.10346 Pab1_F173G,Pab1_173,Pab1,Pab1,P04147,-0.102649,NO,173,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.477,-3.472,1.995,,,E,B,0.87,-0.16,1.636,,63.26,BHA,-1.36967,0.175299,0.00148779,-0.102649 beta-lactamase_625_A132W,beta-lactamase_625_132,TEM-1,beta-lactamase_625,P62593,-0.0945402,NO,132,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.9,-5.372,4.472,,,H,A,0.46,-0.93,0.316,,64.69,PHH,-1.138,0.213352,0.000962524,-0.0945402 beta-lactamase_156_Y262K,beta-lactamase_156_262,TEM-1,beta-lactamase_156,P62593,-0.0925911,NO,262,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.111618,0.00853516,-0.0925911 beta-lactamase_39_F64D,beta-lactamase_39_64,TEM-1,beta-lactamase_39,P62593,-0.0904569,NO,64,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-0.841,-3.919,3.078,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.0495842,0.000947691,-0.0904569 beta-lactamase_156_G234K,beta-lactamase_156_234,TEM-1,beta-lactamase_156,P62593,-0.0898708,NO,234,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.62,-3.682,3.062,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.111618,0.000889577,-0.0898708 beta-lactamase_156_W227D,beta-lactamase_156_227,TEM-1,beta-lactamase_156,P62593,-0.0897932,NO,227,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-0.982,-4.076,3.094,,0.272,,B,0.47,-0.29,2.533,,74.48,OHH,-1.595,0.111618,0.00226019,-0.0897932 kka2_1:8_M197S,kka2_1:8_197,Kka2,kka2_1:8,P00552,-0.0888196,NO,197,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.707,-3.643,1.936,,0.121,E,B,1.59,-1.19,4.408,,65.53,HHH,-1.847,0.100394,0.00921295,-0.0888196 kka2_1:8_M197S,kka2_1:8_197,Kka2,kka2_1:8,P00552,-0.0888196,NO,197,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.707,-3.643,1.936,,0.121,E,B,1.59,-1.19,4.408,,65.53,HHH,-1.847,0.100394,0.00921295,-0.0888196 Ubiquitin_V17K,Ubiquitin_17,Uba1,Ubiquitin,P0CG48,-0.0887097,NO,17,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.314,-3.743,2.429,5.26282,0.017,,B,2.78,-0.77,3.239,,71.82,AHA,-1.51833,0.205827,0.000659638,-0.0887097 PSD95pdz3_I338W,PSD95pdz3_338,PSD95pdz3,PSD95pdz3,P31016,-0.0859345,NO,338,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.63,-5.004,3.374,5.45113,,,,,13.0087,,,,HHP,-1.55767,0.0758425,0.000862587,-0.0859345 kka2_1:1_A172W,kka2_1:1_172,Kka2,kka2_1:1,P00552,-0.0857515,NO,172,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.757,-5.588,3.831,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.520039,0.0079265,-0.0857515 Pab1_G150P,Pab1_150,Pab1,Pab1,P04147,-0.0837212,NO,150,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.809,-3.697,2.888,,0.287,S,b,0.23,0.53,,,,HOA,-1.45233,0.175299,0.000323835,-0.0837212 beta-lactamase_625_G234I,beta-lactamase_625_234,TEM-1,beta-lactamase_625,P62593,-0.0815782,NO,234,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.62,-4.235,3.615,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.213352,0.000889577,-0.0815782 beta-lactamase_0_V117D,beta-lactamase_0_117,TEM-1,beta-lactamase_0,P62593,-0.0798146,NO,117,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.53,-4.116,2.586,,,H,A,0.44,-0.34,1.16,,65.03,PHB,-1.741,0.0500837,0.00467906,-0.0798146 kka2_1:1_G74E,kka2_1:1_74,Kka2,kka2_1:1,P00552,-0.0791383,NO,74,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.18,-2.749,1.569,,0.621,T,l,0.75,0.2,15.356,15.356,64.39,POH,-1.91667,0.520039,0.00587035,-0.0791383 kka2_1:8_N195I,kka2_1:8_195,Kka2,kka2_1:8,P00552,-0.0790055,NO,195,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-0.836,-4.062,3.226,,0.037,G,A,0.43,-1.36,1.108,,48.11,OPH,-1.26567,0.100394,0.00276134,-0.0790055 kka2_1:8_N195I,kka2_1:8_195,Kka2,kka2_1:8,P00552,-0.0790055,NO,195,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-0.836,-4.062,3.226,,0.037,G,A,0.43,-1.36,1.108,,48.11,OPH,-1.26567,0.100394,0.00276134,-0.0790055 beta-lactamase_156_G243I,beta-lactamase_156_243,TEM-1,beta-lactamase_156,P62593,-0.0789281,NO,243,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.532,-3.58,2.048,,,E,B,0.77,-1.24,2.866,,50,BOH,-1.46867,0.111618,0.00464034,-0.0789281 beta-lactamase_39_G243K,beta-lactamase_39_243,TEM-1,beta-lactamase_39,P62593,-0.0784497,NO,243,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.0495842,0.00464034,-0.0784497 kka2_1:2_T187P,kka2_1:2_187,Kka2,kka2_1:2,P00552,-0.0756182,NO,187,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.273,-3.887,2.614,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.295029,0.00693073,-0.0756182 beta-lactamase_39_K71H,beta-lactamase_39_71,TEM-1,beta-lactamase_39,P62593,-0.0755434,NO,71,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-0.8,-4.455,3.655,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.0495842,0.00103192,-0.0755434 beta-lactamase_39_K232W,beta-lactamase_39_232,TEM-1,beta-lactamase_39,P62593,-0.0753498,NO,232,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.012,-5.365,4.353,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.0495842,0.00313441,-0.0753498 WW_domain_G176T,WW_domain_176,Yap65,WW_domain,P46937,-0.0747813,NO,176,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.235,-3.367,2.132,6.33142,,,,,,2.71,,78.57,HOH,-1.35467,0.153962,0.00288552,-0.0747813 E1_Ubiquitin_G76E,E1_Ubiquitin_76,Uba1,E1_Ubiquitin,P0CG63,-0.0742706,NO,76,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.999,-3.586,2.587,,0.23,,B,0.75,0.08,1.702,,83.73,OOO,-0.999,0.18783,0.00125575,-0.0742706 hsp90_W585D,hsp90_585,hsp90,hsp90,P02829,-0.0732439,NO,585,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-4.251,-2.847,0,5.31455,0.508,,B,1.22,0.43,,,,OHP,-3.17533,0.368192,0.000222939,-0.0732439 kka2_1:8_I228Y,kka2_1:8_228,Kka2,kka2_1:8,P00552,-0.0724784,NO,228,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.142,-4.038,2.896,,,H,A,1.52,-1.2,1.521,,71.59,AHH,-1.54633,0.100394,0.00458834,-0.0724784 kka2_1:8_I228Y,kka2_1:8_228,Kka2,kka2_1:8,P00552,-0.0724784,NO,228,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.142,-4.038,2.896,,,H,A,1.52,-1.2,1.521,,71.59,AHH,-1.54633,0.100394,0.00458834,-0.0724784 kka2_1:4_T73P,kka2_1:4_73,Kka2,kka2_1:4,P00552,-0.0712509,NO,73,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.51,-4.057,1.547,,0.309,H,A,0.22,0.35,1.53,,56.06,PPO,-2.02333,0.168804,0.00628605,-0.0712509 kka2_1:2_H135S,kka2_1:2_135,Kka2,kka2_1:2,P00552,-0.0709712,NO,135,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-1.331,-3.439,2.108,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.295029,0.00532566,-0.0709712 kka2_1:1_A172P,kka2_1:1_172,Kka2,kka2_1:1,P00552,-0.0707482,NO,172,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.757,-4.041,2.284,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.520039,0.0079265,-0.0707482 beta-lactamase_625_G234Q,beta-lactamase_625_234,TEM-1,beta-lactamase_625,P62593,-0.0697018,NO,234,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.62,-4.124,3.504,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.213352,0.000889577,-0.0697018 beta-lactamase_39_I261D,beta-lactamase_39_261,TEM-1,beta-lactamase_39,P62593,-0.0665159,NO,261,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.0495842,0.0123091,-0.0665159 beta-lactamase_156_I245H,beta-lactamase_156_245,TEM-1,beta-lactamase_156,P62593,-0.0654175,NO,245,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.111618,0.00391032,-0.0654175 PSD95pdz3_G329L,PSD95pdz3_329,PSD95pdz3,PSD95pdz3,P31016,-0.0634383,NO,329,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.008,-3.49,2.482,4.7671,,,,,19.7075,,,,HOO,-1.16033,0.0758425,0.000974577,-0.0634383 kka2_1:8_L193N,kka2_1:8_193,Kka2,kka2_1:8,P00552,-0.0627156,NO,193,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.983,-4.109,3.126,,,G,A,1.59,-1.03,2.234,,65.53,OHO,-0.965333,0.100394,0.00480179,-0.0627156 kka2_1:8_L193N,kka2_1:8_193,Kka2,kka2_1:8,P00552,-0.0627156,NO,193,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.983,-4.109,3.126,,,G,A,1.59,-1.03,2.234,,65.53,OHO,-0.965333,0.100394,0.00480179,-0.0627156 beta-lactamase_156_W227N,beta-lactamase_156_227,TEM-1,beta-lactamase_156,P62593,-0.0618261,NO,227,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-0.982,-4.236,3.254,,0.272,,B,0.47,-0.29,2.533,,74.48,OHH,-1.595,0.111618,0.00226019,-0.0618261 kka2_1:2_D157I,kka2_1:2_157,Kka2,kka2_1:2,P00552,-0.060839,NO,157,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.993,-4.127,3.134,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.295029,0.0042313,-0.060839 kka2_1:1_R173N,kka2_1:1_173,Kka2,kka2_1:1,P00552,-0.0599826,NO,173,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.407,-3.101,0.694,,0.308,H,A,0.16,-0.13,14.756,14.756,65.53,HBH,-1.70533,0.520039,0.00784999,-0.0599826 Pab1_G169Q,Pab1_169,Pab1,Pab1,P04147,-0.0596275,NO,169,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.809,-3.941,3.132,,,E,b,0.35,0.03,,,,HOH,-1.11567,0.175299,0.000302434,-0.0596275 kka2_1:1_L47A,kka2_1:1_47,Kka2,kka2_1:1,P00552,-0.0593422,NO,47,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.265,-2.449,1.184,,0.139,E,B,0.55,-0.86,14.593,14.593,63.26,HHH,-1.77933,0.520039,0.00509386,-0.0593422 beta-lactamase_2500_W227P,beta-lactamase_2500_227,TEM-1,beta-lactamase_2500,P62593,-0.0585979,NO,227,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-0.982,-4.323,3.341,,0.272,,B,0.47,-0.29,1.37,,74.48,OHH,-1.595,0.361275,0.00226019,-0.0585979 beta-lactamase_2500_K71A,beta-lactamase_2500_71,TEM-1,beta-lactamase_2500,P62593,-0.0583066,NO,71,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-0.8,-3.078,2.278,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.361275,0.00103192,-0.0583066 beta-lactamase_2500_G43L,beta-lactamase_2500_43,TEM-1,beta-lactamase_2500,P62593,-0.058113,NO,43,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.62,-3.808,3.188,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.361275,0.00120151,-0.058113 beta-lactamase_625_N134E,beta-lactamase_625_134,TEM-1,beta-lactamase_625,P62593,-0.0550141,NO,134,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-0.879,-3.212,2.333,,0.138,H,A,0.61,-0.6,3.776,,53.15,HPH,-1.02233,0.213352,0.000644786,-0.0550141 PSD95pdz3_I338H,PSD95pdz3_338,PSD95pdz3,PSD95pdz3,P31016,-0.0545893,NO,338,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.63,-4.587,2.957,5.45113,,,,,13.0087,,,,HHP,-1.55767,0.0758425,0.000862587,-0.0545893 beta-lactamase_156_E164Q,beta-lactamase_156_164,TEM-1,beta-lactamase_156,P62593,-0.0538827,NO,164,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-0.948,-3.358,2.41,,0.011,T,B,1.04,-0.4,3.445,,64.69,HAO,-1.388,0.111618,0.00137286,-0.0538827 beta-lactamase_156_S68E,beta-lactamase_156_68,TEM-1,beta-lactamase_156,P62593,-0.053709,NO,68,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-0.913,-3.241,2.328,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.111618,0.000800065,-0.053709 kka2_1:4_V36W,kka2_1:4_36,Kka2,kka2_1:4,P00552,-0.0533959,NO,36,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-0.898,-5.395,4.497,,0.292,E,B,0.44,0.21,0.278,,52.27,HHH,-1.484,0.168804,0.00245633,-0.0533959 beta-lactamase_625_S68E,beta-lactamase_625_68,TEM-1,beta-lactamase_625,P62593,-0.0530727,NO,68,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-0.913,-3.241,2.328,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.213352,0.000800065,-0.0530727 kka2_1:1_R173I,kka2_1:1_173,Kka2,kka2_1:1,P00552,-0.0527584,NO,173,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.407,-4.054,1.647,,0.308,H,A,0.16,-0.13,14.756,14.756,65.53,HBH,-1.70533,0.520039,0.00784999,-0.0527584 PSD95pdz3_H372W,PSD95pdz3_372,PSD95pdz3,PSD95pdz3,P31016,-0.0524705,NO,372,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-1.627,-4.779,3.152,5.5607,,,,,17.008,,,,PBA,-1.63033,0.0758425,0.00040301,-0.0524705 beta-lactamase_2500_P181R,beta-lactamase_2500_181,TEM-1,beta-lactamase_2500,P62593,-0.0521722,NO,181,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.813,-3.93,3.117,,,H,A,0.52,-1.14,1.946,,61.54,HOH,-1.795,0.361275,0.000703122,-0.0521722 beta-lactamase_39_E164C,beta-lactamase_39_164,TEM-1,beta-lactamase_39,P62593,-0.0520733,NO,164,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-0.948,-5.311,4.363,,0.011,T,B,1.04,-0.4,0.664,,64.69,HAO,-1.388,0.0495842,0.00137286,-0.0520733 beta-lactamase_156_D129A,beta-lactamase_156_129,TEM-1,beta-lactamase_156,P62593,-0.051527,NO,129,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.816,-3.3,2.484,,,,B,0.75,-0.69,1.924,,34.97,PAP,-0.818,0.111618,0.00109178,-0.051527 kka2_1:4_L94H,kka2_1:4_94,Kka2,kka2_1:4,P00552,-0.0507065,NO,94,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.618,-4.931,3.313,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.168804,0.00520888,-0.0507065 beta-lactamase_625_E164H,beta-lactamase_625_164,TEM-1,beta-lactamase_625,P62593,-0.0498342,NO,164,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-0.948,-4.339,3.391,,0.011,T,B,1.04,-0.4,1.321,,64.69,HAO,-1.388,0.213352,0.00137286,-0.0498342 kka2_1:1_A78W,kka2_1:1_78,Kka2,kka2_1:1,P00552,-0.0494486,NO,78,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.744,-5.551,3.807,,0.078,.,B,0.46,-0.53,0.206,,56.06,OHH,-1.863,0.520039,0.00457299,-0.0494486 kka2_1:4_G189E,kka2_1:4_189,Kka2,kka2_1:4,P00552,-0.0490984,NO,189,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.596,-3.693,3.097,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.168804,0.00253688,-0.0490984 kka2_1:2_A172W,kka2_1:2_172,Kka2,kka2_1:2,P00552,-0.0484864,NO,172,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.757,-5.588,3.831,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.295029,0.0079265,-0.0484864 kka2_1:2_G164I,kka2_1:2_164,Kka2,kka2_1:2,P00552,-0.0483425,NO,164,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.869,-4.238,3.369,,0.862,T,l,0.75,1.45,1.539,,64.39,POH,-1.828,0.295029,0.00442091,-0.0483425 beta-lactamase_2500_D155L,beta-lactamase_2500_155,TEM-1,beta-lactamase_2500,P62593,-0.0470863,NO,155,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.889,-3.807,2.918,,0.049,,B,0.75,-0.9,2.386,,64.69,OAB,-1.62267,0.361275,0.00135315,-0.0470863 kka2_1:4_N195A,kka2_1:4_195,Kka2,kka2_1:4,P00552,-0.0460847,NO,195,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-0.836,-3.354,2.518,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.168804,0.00276134,-0.0460847 beta-lactamase_625_A185W,beta-lactamase_625_185,TEM-1,beta-lactamase_625,P62593,-0.0451106,NO,185,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.406,-5.387,3.981,,,H,A,0.46,-1.02,0.365,,65.03,HHP,-1.84033,0.213352,0.00467449,-0.0451106 kka2_1:1_G74I,kka2_1:1_74,Kka2,kka2_1:1,P00552,-0.04496,NO,74,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.18,-4.265,3.085,,0.621,T,l,0.75,0.2,15.356,15.356,64.39,POH,-1.91667,0.520039,0.00587035,-0.04496 kka2_1:1_V75G,kka2_1:1_75,Kka2,kka2_1:1,P00552,-0.0445781,NO,75,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-2.06,-3.863,1.803,,0.042,.,B,0.44,-0.2,2.815,,71.59,OHO,-1.563,0.520039,0.00693733,-0.0445781 beta-lactamase_156_G43Y,beta-lactamase_156_43,TEM-1,beta-lactamase_156,P62593,-0.0444734,NO,43,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.62,-4.387,3.767,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.111618,0.00120151,-0.0444734 kka2_1:8_G213N,kka2_1:8_213,Kka2,kka2_1:8,P00552,-0.0444154,NO,213,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.596,-3.476,2.88,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.100394,0.00187654,-0.0444154 kka2_1:8_G213N,kka2_1:8_213,Kka2,kka2_1:8,P00552,-0.0444154,NO,213,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.596,-3.476,2.88,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.100394,0.00187654,-0.0444154 beta-lactamase_156_S68K,beta-lactamase_156_68,TEM-1,beta-lactamase_156,P62593,-0.0442125,NO,68,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-0.913,-3.258,2.345,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.111618,0.000800065,-0.0442125 beta-lactamase_39_T179E,beta-lactamase_39_179,TEM-1,beta-lactamase_39,P62593,-0.044032,NO,179,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.085,-3.446,2.361,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.0495842,0.00226045,-0.044032 beta-lactamase_156_G76K,beta-lactamase_156_76,TEM-1,beta-lactamase_156,P62593,-0.0419858,NO,76,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.189,-3.631,2.442,,,H,A,0.29,-0.67,3.059,,67.83,OOH,-1.22267,0.111618,0.00476637,-0.0419858 beta-lactamase_156_T158K,beta-lactamase_156_158,TEM-1,beta-lactamase_156,P62593,-0.0418947,NO,158,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.116,-3.466,2.35,,0.036,,B,0.22,-0.85,3.771,,69.58,HPB,-1.269,0.111618,0.00341825,-0.0418947 kka2_1:1_T73G,kka2_1:1_73,Kka2,kka2_1:1,P00552,-0.0412537,NO,73,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.51,-3.619,1.109,,0.309,H,A,0.22,0.35,4.126,,56.06,PPO,-2.02333,0.520039,0.00628605,-0.0412537 beta-lactamase_39_S128Q,beta-lactamase_39_128,TEM-1,beta-lactamase_39,P62593,-0.0411634,NO,128,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-0.84,-3.674,2.834,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.0495842,0.00071483,-0.0411634 kka2_1:8_D261I,kka2_1:8_261,Kka2,kka2_1:8,P00552,-0.0404836,NO,261,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.708,-4.039,3.331,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.100394,0.0224846,-0.0404836 kka2_1:8_D261I,kka2_1:8_261,Kka2,kka2_1:8,P00552,-0.0404836,NO,261,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.708,-4.039,3.331,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.100394,0.0224846,-0.0404836 beta-lactamase_625_A132R,beta-lactamase_625_132,TEM-1,beta-lactamase_625,P62593,-0.0403855,NO,132,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.9,-3.795,2.895,,,H,A,0.46,-0.93,0.316,,64.69,PHH,-1.138,0.213352,0.000962524,-0.0403855 beta-lactamase_39_K71D,beta-lactamase_39_71,TEM-1,beta-lactamase_39,P62593,-0.040266,NO,71,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-0.8,-3.469,2.669,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.0495842,0.00103192,-0.040266 kka2_1:1_V80E,kka2_1:1_80,Kka2,kka2_1:1,P00552,-0.0395996,NO,80,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.144,-3.785,2.641,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.520039,0.00488211,-0.0395996 beta-lactamase_2500_I244R,beta-lactamase_2500_244,TEM-1,beta-lactamase_2500,P62593,-0.0393767,NO,244,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.555,-4.183,2.628,,,E,B,0.48,-0.84,1.683,,77.62,OHH,-1.385,0.361275,0.00605379,-0.0393767 PSD95pdz3_G329K,PSD95pdz3_329,PSD95pdz3,PSD95pdz3,P31016,-0.0390102,NO,329,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.008,-3.364,2.356,4.7671,,,,,19.7075,,,,HOO,-1.16033,0.0758425,0.000974577,-0.0390102 beta-lactamase_0_A123P,beta-lactamase_0_123,TEM-1,beta-lactamase_0,P62593,-0.0389806,NO,123,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.834,-3.704,2.87,,0.039,H,A,0.46,-0.72,1.308,,41.26,PHH,-1.47367,0.0500837,0.0010157,-0.0389806 kka2_1:4_A78I,kka2_1:4_78,Kka2,kka2_1:4,P00552,-0.0375957,NO,78,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.744,-3.934,2.19,,0.078,.,B,0.46,-0.53,0.594,,56.06,OHH,-1.863,0.168804,0.00457299,-0.0375957 kka2_1:2_D33I,kka2_1:2_33,Kka2,kka2_1:2,P00552,-0.0375165,NO,33,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.186,-4.175,1.989,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.295029,0.00633568,-0.0375165 kka2_1:1_G74K,kka2_1:1_74,Kka2,kka2_1:1,P00552,-0.0373604,NO,74,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.18,-3.609,2.429,,0.621,T,l,0.75,0.2,15.356,15.356,64.39,POH,-1.91667,0.520039,0.00587035,-0.0373604 beta-lactamase_156_S68M,beta-lactamase_156_68,TEM-1,beta-lactamase_156,P62593,-0.0369413,NO,68,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-0.913,-4.529,3.616,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.111618,0.000800065,-0.0369413 beta-lactamase_156_F64N,beta-lactamase_156_64,TEM-1,beta-lactamase_156,P62593,-0.0368717,NO,64,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-0.841,-4.123,3.282,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.111618,0.000947691,-0.0368717 kka2_1:4_E262A,kka2_1:4_262,Kka2,kka2_1:4,P00552,-0.0361327,NO,262,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-0.829,-3.129,2.3,,0.059,G,A,1.04,-0.18,2.383,,42.42,AAH,-0.816,0.168804,0.0191586,-0.0361327 kka2_1:8_P194E,kka2_1:8_194,Kka2,kka2_1:8,P00552,-0.0354416,NO,194,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.846,-3.407,2.561,,0.308,G,A,0.52,-1.19,4.861,,53.03,HOP,-0.888333,0.100394,0.00314194,-0.0354416 kka2_1:8_P194E,kka2_1:8_194,Kka2,kka2_1:8,P00552,-0.0354416,NO,194,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.846,-3.407,2.561,,0.308,G,A,0.52,-1.19,4.861,,53.03,HOP,-0.888333,0.100394,0.00314194,-0.0354416 kka2_1:8_W236N,kka2_1:8_236,Kka2,kka2_1:8,P00552,-0.035057,NO,236,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-1.363,-4.289,2.926,,0.303,H,A,1.51,-0.76,1.87,,48.48,AHH,-1.81267,0.100394,0.0088796,-0.035057 kka2_1:8_W236N,kka2_1:8_236,Kka2,kka2_1:8,P00552,-0.035057,NO,236,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-1.363,-4.289,2.926,,0.303,H,A,1.51,-0.76,1.87,,48.48,AHH,-1.81267,0.100394,0.0088796,-0.035057 beta-lactamase_625_A185N,beta-lactamase_625_185,TEM-1,beta-lactamase_625,P62593,-0.0347771,NO,185,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.406,-4.005,2.599,,,H,A,0.46,-1.02,0.365,,65.03,HHP,-1.84033,0.213352,0.00467449,-0.0347771 kka2_1:8_F171E,kka2_1:8_171,Kka2,kka2_1:8,P00552,-0.0346727,NO,171,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.326,-3.96,2.634,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.100394,0.00821426,-0.0346727 kka2_1:8_F171E,kka2_1:8_171,Kka2,kka2_1:8,P00552,-0.0346727,NO,171,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.326,-3.96,2.634,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.100394,0.00821426,-0.0346727 kka2_1:4_T187K,kka2_1:4_187,Kka2,kka2_1:4,P00552,-0.034518,NO,187,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.273,-3.655,2.382,,0.007,E,B,0.22,-0.85,2.73,,52.27,HPB,-1.06567,0.168804,0.00693073,-0.034518 beta-lactamase_2500_F64S,beta-lactamase_2500_64,TEM-1,beta-lactamase_2500,P62593,-0.0341966,NO,64,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-0.841,-3.611,2.77,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.361275,0.000947691,-0.0341966 beta-lactamase_0_T126Y,beta-lactamase_0_126,TEM-1,beta-lactamase_0,P62593,-0.0337663,NO,126,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.122,-4.294,3.172,,0.05,H,A,0.22,-0.05,0.705,,44.41,HPH,-1.60467,0.0500837,0.00244552,-0.0337663 kka2_1:2_E59I,kka2_1:2_59,Kka2,kka2_1:2,P00552,-0.0337171,NO,59,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-0.952,-4.057,3.105,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.295029,0.00280355,-0.0337171 kka2_1:8_D157I,kka2_1:8_157,Kka2,kka2_1:8,P00552,-0.0331404,NO,157,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.993,-4.127,3.134,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.100394,0.0042313,-0.0331404 kka2_1:8_D157I,kka2_1:8_157,Kka2,kka2_1:8,P00552,-0.0331404,NO,157,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.993,-4.127,3.134,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.100394,0.0042313,-0.0331404 beta-lactamase_39_S68V,beta-lactamase_39_68,TEM-1,beta-lactamase_39,P62593,-0.0328269,NO,68,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-0.913,-3.578,2.665,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.0495842,0.000800065,-0.0328269 beta-lactamase_625_P181D,beta-lactamase_625_181,TEM-1,beta-lactamase_625,P62593,-0.0328234,NO,181,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.813,-3.518,2.705,,,H,A,0.52,-1.14,1.797,,61.54,HOH,-1.795,0.213352,0.000703122,-0.0328234 Pab1_F170G,Pab1_170,Pab1,Pab1,P04147,-0.0322951,NO,170,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.269,-3.454,2.185,,0.331,E,B,0.87,-1.31,2.061,,79.72,OHH,-1.06367,0.175299,0.000540225,-0.0322951 beta-lactamase_2500_L74H,beta-lactamase_2500_74,TEM-1,beta-lactamase_2500,P62593,-0.0320841,NO,74,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.296,-4.896,3.6,,,H,A,0.55,-0.91,0.746,,50,HHO,-1.34933,0.361275,0.00493255,-0.0320841 beta-lactamase_2500_N134P,beta-lactamase_2500_134,TEM-1,beta-lactamase_2500,P62593,-0.0320457,NO,134,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-0.879,-3.877,2.998,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.361275,0.000644786,-0.0320457 beta-lactamase_156_G43D,beta-lactamase_156_43,TEM-1,beta-lactamase_156,P62593,-0.0316676,NO,43,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.62,-3.469,2.849,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.111618,0.00120151,-0.0316676 beta-lactamase_625_L136W,beta-lactamase_625_136,TEM-1,beta-lactamase_625,P62593,-0.031131,NO,136,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.232,-5.281,4.049,,,H,A,0.55,-0.34,0.336,,48.95,HHH,-1.088,0.213352,0.00442304,-0.031131 beta-lactamase_2500_G76H,beta-lactamase_2500_76,TEM-1,beta-lactamase_2500,P62593,-0.0310114,NO,76,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.189,-4.754,3.565,,,H,A,0.29,-0.67,1.012,,67.83,OOH,-1.22267,0.361275,0.00476637,-0.0310114 kka2_1:2_A78K,kka2_1:2_78,Kka2,kka2_1:2,P00552,-0.0308926,NO,78,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.744,-3.53,1.786,,0.078,.,B,0.46,-0.53,0.206,,56.06,OHH,-1.863,0.295029,0.00457299,-0.0308926 beta-lactamase_39_V259P,beta-lactamase_39_259,TEM-1,beta-lactamase_39,P62593,-0.0303228,NO,259,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.0495842,0.0070773,-0.0303228 kka2_1:2_V80E,kka2_1:2_80,Kka2,kka2_1:2,P00552,-0.0303122,NO,80,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.144,-3.785,2.641,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.295029,0.00488211,-0.0303122 kka2_1:4_C77Y,kka2_1:4_77,Kka2,kka2_1:4,P00552,-0.0301358,NO,77,C,Y,CY,Special,Hydrophobic,5.07,5.66,0.59,194,121,181,60,108.5,193.6,85.1,-1.477,-4.33,2.853,,0.229,B,b,0.46,-0.57,2.499,,63.26,OOH,-1.55667,0.168804,0.00441216,-0.0301358 PSD95pdz3_I327H,PSD95pdz3_327,PSD95pdz3,PSD95pdz3,P31016,-0.0293511,NO,327,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.63,-4.587,2.957,5.7413,,,,,14.0388,,,,PHH,-1.50167,0.0758425,0.000998774,-0.0293511 kka2_1:4_A78K,kka2_1:4_78,Kka2,kka2_1:4,P00552,-0.029293,NO,78,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.744,-3.53,1.786,,0.078,.,B,0.46,-0.53,0.594,,56.06,OHH,-1.863,0.168804,0.00457299,-0.029293 kka2_1:8_C209E,kka2_1:8_209,Kka2,kka2_1:8,P00552,-0.028963,NO,209,C,E,CE,Special,negativeCharge,5.07,3.22,-1.85,170,121,147,26,108.5,138.4,29.9,-0.906,-4.141,3.235,,,,a,1.5,-0.89,0.391,,19.32,AOO,-0.903,0.100394,0.00260862,-0.028963 kka2_1:8_C209E,kka2_1:8_209,Kka2,kka2_1:8,P00552,-0.028963,NO,209,C,E,CE,Special,negativeCharge,5.07,3.22,-1.85,170,121,147,26,108.5,138.4,29.9,-0.906,-4.141,3.235,,,,a,1.5,-0.89,0.391,,19.32,AOO,-0.903,0.100394,0.00260862,-0.028963 kka2_1:2_V75G,kka2_1:2_75,Kka2,kka2_1:2,P00552,-0.0284304,NO,75,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-2.06,-3.863,1.803,,0.042,.,B,0.44,-0.2,2.815,,71.59,OHO,-1.563,0.295029,0.00693733,-0.0284304 kka2_1:4_G213Q,kka2_1:4_213,Kka2,kka2_1:4,P00552,-0.0283733,NO,213,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.596,-4.153,3.557,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.168804,0.00187654,-0.0283733 beta-lactamase_625_F64C,beta-lactamase_625_64,TEM-1,beta-lactamase_625,P62593,-0.0282761,NO,64,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-0.841,-4.862,4.021,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.213352,0.000947691,-0.0282761 beta-lactamase_625_E164M,beta-lactamase_625_164,TEM-1,beta-lactamase_625,P62593,-0.0279717,NO,164,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-0.948,-4.749,3.801,,0.011,T,B,1.04,-0.4,1.321,,64.69,HAO,-1.388,0.213352,0.00137286,-0.0279717 beta-lactamase_625_K71Y,beta-lactamase_625_71,TEM-1,beta-lactamase_625,P62593,-0.027521,NO,71,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-0.8,-4.162,3.362,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.213352,0.00103192,-0.027521 beta-lactamase_39_I280D,beta-lactamase_39_280,TEM-1,beta-lactamase_39,P62593,-0.0271532,NO,280,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.0495842,0.0530888,-0.0271532 kka2_1:2_A78M,kka2_1:2_78,Kka2,kka2_1:2,P00552,-0.0271359,NO,78,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.744,-4.709,2.965,,0.078,.,B,0.46,-0.53,0.206,,56.06,OHH,-1.863,0.295029,0.00457299,-0.0271359 kka2_1:2_L19N,kka2_1:2_19,Kka2,kka2_1:2,P00552,-0.0270873,NO,19,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.254,-4.186,2.932,,0.08,T,A,0.55,-0.26,17.165,17.165,65.53,BHH,-2.221,0.295029,0.00620703,-0.0270873 kka2_1:8_M197Y,kka2_1:8_197,Kka2,kka2_1:8,P00552,-0.0267066,NO,197,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.707,-4.145,2.438,,0.121,E,B,1.59,-1.19,4.408,,65.53,HHH,-1.847,0.100394,0.00921295,-0.0267066 kka2_1:8_M197Y,kka2_1:8_197,Kka2,kka2_1:8,P00552,-0.0267066,NO,197,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.707,-4.145,2.438,,0.121,E,B,1.59,-1.19,4.408,,65.53,HHH,-1.847,0.100394,0.00921295,-0.0267066 kka2_1:2_L102I,kka2_1:2_102,Kka2,kka2_1:2,P00552,-0.0242406,NO,102,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.804,-2.957,2.153,,,T,A,1.59,-1.17,4.258,,42.42,AHH,-1.398,0.295029,0.00201332,-0.0242406 kka2_1:4_C77K,kka2_1:4_77,Kka2,kka2_1:4,P00552,-0.0239081,NO,77,C,K,CK,Special,PositiveCharge,5.07,9.74,4.67,202,121,146,25,108.5,168.6,60.1,-1.477,-3.834,2.357,,0.229,B,b,0.46,-0.57,2.499,,63.26,OOH,-1.55667,0.168804,0.00441216,-0.0239081 beta-lactamase_625_W227D,beta-lactamase_625_227,TEM-1,beta-lactamase_625,P62593,-0.0232193,NO,227,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-0.982,-4.076,3.094,,0.272,,B,0.47,-0.29,2.533,,74.48,OHH,-1.595,0.213352,0.00226019,-0.0232193 beta-lactamase_2500_D161P,beta-lactamase_2500_161,TEM-1,beta-lactamase_2500,P62593,-0.0230859,NO,161,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.891,-3.704,2.813,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.361275,0.000897697,-0.0230859 kka2_1:2_V198Y,kka2_1:2_198,Kka2,kka2_1:2,P00552,-0.0211338,NO,198,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.719,-4.264,2.545,,0.05,E,B,1.48,-0.95,1.074,,56.06,HHA,-1.88667,0.295029,0.00835002,-0.0211338 kka2_1:8_G205N,kka2_1:8_205,Kka2,kka2_1:8,P00552,-0.0211326,NO,205,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.596,-3.476,2.88,,,E,b,0.75,-1.05,,,,POH,-1.09933,0.100394,0.00221855,-0.0211326 kka2_1:8_G205N,kka2_1:8_205,Kka2,kka2_1:8,P00552,-0.0211326,NO,205,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.596,-3.476,2.88,,,E,b,0.75,-1.05,,,,POH,-1.09933,0.100394,0.00221855,-0.0211326 kka2_1:4_T73D,kka2_1:4_73,Kka2,kka2_1:4,P00552,-0.0208093,NO,73,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.51,-3.789,1.279,,0.309,H,A,0.22,0.35,1.53,,56.06,PPO,-2.02333,0.168804,0.00628605,-0.0208093 kka2_1:8_L259E,kka2_1:8_259,Kka2,kka2_1:8,P00552,-0.0203965,NO,259,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.088,-3.851,2.763,,0.036,H,A,1.59,-0.15,1.83,,48.48,BHH,-1.15167,0.100394,0.0206964,-0.0203965 kka2_1:8_L259E,kka2_1:8_259,Kka2,kka2_1:8,P00552,-0.0203965,NO,259,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.088,-3.851,2.763,,0.036,H,A,1.59,-0.15,1.83,,48.48,BHH,-1.15167,0.100394,0.0206964,-0.0203965 kka2_1:8_G210N,kka2_1:8_210,Kka2,kka2_1:8,P00552,-0.0200291,NO,210,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.095,-3.653,2.558,,0.103,T,A,0.75,-0.62,2.687,,50,OOB,-0.966667,0.100394,0.00598378,-0.0200291 kka2_1:8_G210N,kka2_1:8_210,Kka2,kka2_1:8,P00552,-0.0200291,NO,210,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.095,-3.653,2.558,,0.103,T,A,0.75,-0.62,2.687,,50,OOB,-0.966667,0.100394,0.00598378,-0.0200291 beta-lactamase_156_S68H,beta-lactamase_156_68,TEM-1,beta-lactamase_156,P62593,-0.019824,NO,68,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-0.913,-4.418,3.505,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.111618,0.000800065,-0.019824 kka2_1:8_R211N,kka2_1:8_211,Kka2,kka2_1:8,P00552,-0.019662,NO,211,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-0.899,-3.561,2.662,,0.12,T,a,0.16,-0.39,0.615,,49.62,OBH,-0.966,0.100394,0.00204888,-0.019662 kka2_1:8_R211N,kka2_1:8_211,Kka2,kka2_1:8,P00552,-0.019662,NO,211,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-0.899,-3.561,2.662,,0.12,T,a,0.16,-0.39,0.615,,49.62,OBH,-0.966,0.100394,0.00204888,-0.019662 Pab1_G169K,Pab1_169,Pab1,Pab1,P04147,-0.0195371,NO,169,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.809,-3.499,2.69,,,E,b,0.35,0.03,,,,HOH,-1.11567,0.175299,0.000302434,-0.0195371 beta-lactamase_2500_F64C,beta-lactamase_2500_64,TEM-1,beta-lactamase_2500,P62593,-0.019393,NO,64,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-0.841,-4.862,4.021,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.361275,0.000947691,-0.019393 kka2_1:2_G189E,kka2_1:2_189,Kka2,kka2_1:2,P00552,-0.0190437,NO,189,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.596,-3.693,3.097,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.295029,0.00253688,-0.0190437 beta-lactamase_156_I245D,beta-lactamase_156_245,TEM-1,beta-lactamase_156,P62593,-0.0177215,NO,245,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.111618,0.00391032,-0.0177215 kka2_1:4_A78N,kka2_1:4_78,Kka2,kka2_1:4,P00552,-0.0174228,NO,78,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.744,-3.971,2.227,,0.078,.,B,0.46,-0.53,0.594,,56.06,OHH,-1.863,0.168804,0.00457299,-0.0174228 kka2_1:8_E59I,kka2_1:8_59,Kka2,kka2_1:8,P00552,-0.0171043,NO,59,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-0.952,-4.057,3.105,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.100394,0.00280355,-0.0171043 kka2_1:8_E59I,kka2_1:8_59,Kka2,kka2_1:8,P00552,-0.0171043,NO,59,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-0.952,-4.057,3.105,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.100394,0.00280355,-0.0171043 beta-lactamase_0_V117H,beta-lactamase_0_117,TEM-1,beta-lactamase_0,P62593,-0.0169385,NO,117,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.53,-4.89,3.36,,,H,A,0.44,-0.34,1.16,,65.03,PHB,-1.741,0.0500837,0.00467906,-0.0169385 kka2_1:8_G88I,kka2_1:8_88,Kka2,kka2_1:8,P00552,-0.0156516,NO,88,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.689,-4.119,2.43,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.100394,0.00685559,-0.0156516 kka2_1:8_G88I,kka2_1:8_88,Kka2,kka2_1:8,P00552,-0.0156516,NO,88,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.689,-4.119,2.43,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.100394,0.00685559,-0.0156516 beta-lactamase_39_I245P,beta-lactamase_39_245,TEM-1,beta-lactamase_39,P62593,-0.0156146,NO,245,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.0495842,0.00391032,-0.0156146 kka2_1:4_G189A,kka2_1:4_189,Kka2,kka2_1:4,P00552,-0.0152657,NO,189,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.596,-2.881,2.285,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.168804,0.00253688,-0.0152657 kka2_1:2_T73D,kka2_1:2_73,Kka2,kka2_1:2,P00552,-0.0150481,NO,73,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.51,-3.789,1.279,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.295029,0.00628605,-0.0150481 kka2_1:4_C77Q,kka2_1:4_77,Kka2,kka2_1:4,P00552,-0.0145387,NO,77,C,Q,CQ,Special,Polar,5.07,6.24429,1.17429,154,121,146,25,108.5,143.8,35.3,-1.477,-4.277,2.8,,0.229,B,b,0.46,-0.57,2.499,,63.26,OOH,-1.55667,0.168804,0.00441216,-0.0145387 kka2_1:2_G74I,kka2_1:2_74,Kka2,kka2_1:2,P00552,-0.0144427,NO,74,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.18,-4.265,3.085,,0.621,T,l,0.75,0.2,1.446,,64.39,POH,-1.91667,0.295029,0.00587035,-0.0144427 beta-lactamase_39_T179K,beta-lactamase_39_179,TEM-1,beta-lactamase_39,P62593,-0.0144128,NO,179,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.085,-3.486,2.401,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.0495842,0.00226045,-0.0144128 kka2_1:1_A79M,kka2_1:1_79,Kka2,kka2_1:1,P00552,-0.013504,NO,79,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.368,-3.668,1.3,,0.563,.,B,0.46,-0.43,7.792,7.792,71.59,HHH,-1.752,0.520039,0.00664821,-0.013504 beta-lactamase_2500_N134C,beta-lactamase_2500_134,TEM-1,beta-lactamase_2500,P62593,-0.0125778,NO,134,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-0.879,-5.113,4.234,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.361275,0.000644786,-0.0125778 kka2_1:8_I207E,kka2_1:8_207,Kka2,kka2_1:8,P00552,-0.0124064,NO,207,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.175,-3.934,2.759,,0.293,,B,1.52,-1.12,1.306,,56.06,HHA,-1.07733,0.100394,0.00611824,-0.0124064 kka2_1:8_I207E,kka2_1:8_207,Kka2,kka2_1:8,P00552,-0.0124064,NO,207,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.175,-3.934,2.759,,0.293,,B,1.52,-1.12,1.306,,56.06,HHA,-1.07733,0.100394,0.00611824,-0.0124064 kka2_1:8_Y218E,kka2_1:8_218,Kka2,kka2_1:8,P00552,-0.0124064,NO,218,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-1.438,-3.729,2.291,,0.122,H,A,1.25,-0.69,2.923,,56.06,BHP,-1.17533,0.100394,0.0126098,-0.0124064 kka2_1:8_Y218E,kka2_1:8_218,Kka2,kka2_1:8,P00552,-0.0124064,NO,218,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-1.438,-3.729,2.291,,0.122,H,A,1.25,-0.69,2.923,,56.06,BHP,-1.17533,0.100394,0.0126098,-0.0124064 beta-lactamase_2500_L136R,beta-lactamase_2500_136,TEM-1,beta-lactamase_2500,P62593,-0.011382,NO,136,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.232,-4.116,2.884,,,H,A,0.55,-0.34,1.36,,48.95,HHH,-1.088,0.361275,0.00442304,-0.011382 beta-lactamase_39_K71Q,beta-lactamase_39_71,TEM-1,beta-lactamase_39,P62593,-0.0109143,NO,71,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-0.8,-3.449,2.649,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.0495842,0.00103192,-0.0109143 beta-lactamase_156_K71Y,beta-lactamase_156_71,TEM-1,beta-lactamase_156,P62593,-0.0106966,NO,71,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-0.8,-4.162,3.362,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.111618,0.00103192,-0.0106966 kka2_1:4_V185W,kka2_1:4_185,Kka2,kka2_1:4,P00552,-0.0104459,NO,185,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.045,-5.383,4.338,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.168804,0.00367031,-0.0104459 kka2_1:4_V186P,kka2_1:4_186,Kka2,kka2_1:4,P00552,-0.00982373,NO,186,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.011,-4.069,3.058,,,E,B,0.44,-0.61,0.679,,45.83,HHP,-1.10967,0.168804,0.00409703,-0.00982373 Pab1_F173P,Pab1_173,Pab1,Pab1,P04147,-0.00880957,NO,173,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.477,-4.112,2.635,,,E,B,0.87,-0.16,1.636,,63.26,BHA,-1.36967,0.175299,0.00148779,-0.00880957 beta-lactamase_2500_L146R,beta-lactamase_2500_146,TEM-1,beta-lactamase_2500,P62593,-0.00872885,NO,146,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.462,-4.192,2.73,,0.007,H,A,0.55,-0.56,1.578,,64.69,AHP,-1.656,0.361275,0.00474542,-0.00872885 kka2_1:2_V186F,kka2_1:2_186,Kka2,kka2_1:2,P00552,-0.00868273,NO,186,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.011,-2.866,1.855,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.295029,0.00409703,-0.00868273 Ubiquitin_I44Y,Ubiquitin_44,Uba1,Ubiquitin,P0CG48,-0.00806452,NO,44,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.566,-3.906,2.34,4.71256,,E,B,0.27,-1.17,5.26,,39.71,HHH,-1.38567,0.205827,0.000613305,-0.00806452 Ubiquitin_Y59T,Ubiquitin_59,Uba1,Ubiquitin,P0CG48,-0.00806452,NO,59,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-1.307,-3.592,2.285,5.05599,0.072,G,A,0.43,-0.74,2.566,,24.53,AHP,-1.568,0.205827,0.000775084,-0.00806452 beta-lactamase_A124F,beta-lactamase_124,TEM-1,beta-lactamase,P62593,-0.00803068,NO,124,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.181,-4.133,2.952,4.58507,,H,A,0.58,-0.9,2.273,,64.34,HHH,-1.152,0.221079,0.00481399,-0.00803068 beta-lactamase_A124H,beta-lactamase_124,TEM-1,beta-lactamase,P62593,-0.00803068,NO,124,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.181,-4.785,3.604,4.58507,,H,A,0.58,-0.9,2.273,,64.34,HHH,-1.152,0.221079,0.00481399,-0.00803068 beta-lactamase_A124P,beta-lactamase_124,TEM-1,beta-lactamase,P62593,-0.00803068,NO,124,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.181,-3.759,2.578,4.58507,,H,A,0.58,-0.9,2.273,,64.34,HHH,-1.152,0.221079,0.00481399,-0.00803068 beta-lactamase_A124Y,beta-lactamase_124,TEM-1,beta-lactamase,P62593,-0.00803068,NO,124,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.181,-4.228,3.047,4.58507,,H,A,0.58,-0.9,2.273,,64.34,HHH,-1.152,0.221079,0.00481399,-0.00803068 beta-lactamase_A132K,beta-lactamase_132,TEM-1,beta-lactamase,P62593,-0.00803068,NO,132,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.9,-3.501,2.601,4.58504,,H,A,2.34,-0.93,2.217,,64.69,PHH,-1.138,0.221079,0.000962524,-0.00803068 beta-lactamase_A132L,beta-lactamase_132,TEM-1,beta-lactamase,P62593,-0.00803068,NO,132,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.9,-3.146,2.246,4.58504,,H,A,2.34,-0.93,2.217,,64.69,PHH,-1.138,0.221079,0.000962524,-0.00803068 beta-lactamase_A132M,beta-lactamase_132,TEM-1,beta-lactamase,P62593,-0.00803068,NO,132,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.9,-4.473,3.573,4.58504,,H,A,2.34,-0.93,2.217,,64.69,PHH,-1.138,0.221079,0.000962524,-0.00803068 beta-lactamase_A132P,beta-lactamase_132,TEM-1,beta-lactamase,P62593,-0.00803068,NO,132,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.9,-3.725,2.825,4.58504,,H,A,2.34,-0.93,2.217,,64.69,PHH,-1.138,0.221079,0.000962524,-0.00803068 beta-lactamase_A133L,beta-lactamase_133,TEM-1,beta-lactamase,P62593,-0.00803068,NO,133,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.186,-3.396,2.21,4.86423,,H,A,0.55,-0.86,2.649,,67.83,HHP,-0.988333,0.221079,0.00468022,-0.00803068 beta-lactamase_A133Q,beta-lactamase_133,TEM-1,beta-lactamase,P62593,-0.00803068,NO,133,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.186,-4.056,2.87,4.86423,,H,A,0.55,-0.86,2.649,,67.83,HHP,-0.988333,0.221079,0.00468022,-0.00803068 beta-lactamase_A185K,beta-lactamase_185,TEM-1,beta-lactamase,P62593,-0.00803068,NO,185,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.406,-3.666,2.26,4.89877,,H,A,2.34,-1.02,2.999,,65.03,HHP,-1.84033,0.221079,0.00467449,-0.00803068 beta-lactamase_A185R,beta-lactamase_185,TEM-1,beta-lactamase,P62593,-0.00803068,NO,185,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.406,-3.963,2.557,4.89877,,H,A,2.34,-1.02,2.999,,65.03,HHP,-1.84033,0.221079,0.00467449,-0.00803068 beta-lactamase_A185Y,beta-lactamase_185,TEM-1,beta-lactamase,P62593,-0.00803068,NO,185,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.406,-4.227,2.821,4.89877,,H,A,2.34,-1.02,2.999,,65.03,HHP,-1.84033,0.221079,0.00467449,-0.00803068 beta-lactamase_A245H,beta-lactamase_245,TEM-1,beta-lactamase,P62593,-0.00803068,NO,245,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.068,-4.751,3.683,4.78972,,E,B,0.17,-0.92,0.831,,64.69,HHH,-1.58133,0.221079,0.00391032,-0.00803068 beta-lactamase_C121K,beta-lactamase_121,TEM-1,beta-lactamase,P62593,-0.00803068,NO,121,C,K,CK,Special,PositiveCharge,5.07,9.74,4.67,202,121,146,25,108.5,168.6,60.1,-0.953,-3.72,2.767,5.12205,,H,A,2.8,-0.81,7.644,,63.29,HOP,-1.46767,0.221079,0.000744322,-0.00803068 beta-lactamase_C121P,beta-lactamase_121,TEM-1,beta-lactamase,P62593,-0.00803068,NO,121,C,P,CP,Special,Special,5.07,6.3,1.23,169,121,115,-6,108.5,112.7,4.2,-0.953,-4.102,3.149,5.12205,,H,A,2.8,-0.81,7.644,,63.29,HOP,-1.46767,0.221079,0.000744322,-0.00803068 beta-lactamase_C121R,beta-lactamase_121,TEM-1,beta-lactamase,P62593,-0.00803068,NO,121,C,R,CR,Special,PositiveCharge,5.07,6.34148,1.27148,180,121,174,53,108.5,173.4,64.9,-0.953,-2.762,1.809,5.12205,,H,A,2.8,-0.81,7.644,,63.29,HOP,-1.46767,0.221079,0.000744322,-0.00803068 beta-lactamase_C121W,beta-lactamase_121,TEM-1,beta-lactamase,P62593,-0.00803068,NO,121,C,W,CW,Special,Hydrophobic,5.07,5.89,0.82,215,121,204,83,108.5,227.8,119.3,-0.953,-5.146,4.193,5.12205,,H,A,2.8,-0.81,7.644,,63.29,HOP,-1.46767,0.221079,0.000744322,-0.00803068 beta-lactamase_C75Y,beta-lactamase_75,TEM-1,beta-lactamase,P62593,-0.00803068,NO,75,C,Y,CY,Special,Hydrophobic,5.07,5.66,0.59,194,121,181,60,108.5,193.6,85.1,-1.245,-4.265,3.02,4.88171,,H,A,0.25,-0.87,0.876,,50,HOO,-1.24333,0.221079,0.0034616,-0.00803068 beta-lactamase_D129F,beta-lactamase_129,TEM-1,beta-lactamase,P62593,-0.00803068,NO,129,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.816,-4.318,3.502,4.84204,,,B,1.33,-0.69,0.548,,34.97,PAP,-0.818,0.221079,0.00109178,-0.00803068 beta-lactamase_D129I,beta-lactamase_129,TEM-1,beta-lactamase,P62593,-0.00803068,NO,129,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.816,-4.036,3.22,4.84204,,,B,1.33,-0.69,0.548,,34.97,PAP,-0.818,0.221079,0.00109178,-0.00803068 beta-lactamase_D129M,beta-lactamase_129,TEM-1,beta-lactamase,P62593,-0.00803068,NO,129,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.816,-4.927,4.111,4.84204,,,B,1.33,-0.69,0.548,,34.97,PAP,-0.818,0.221079,0.00109178,-0.00803068 beta-lactamase_D129P,beta-lactamase_129,TEM-1,beta-lactamase,P62593,-0.00803068,NO,129,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.816,-3.68,2.864,4.84204,,,B,1.33,-0.69,0.548,,34.97,PAP,-0.818,0.221079,0.00109178,-0.00803068 beta-lactamase_D129Q,beta-lactamase_129,TEM-1,beta-lactamase,P62593,-0.00803068,NO,129,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.816,-3.637,2.821,4.84204,,,B,1.33,-0.69,0.548,,34.97,PAP,-0.818,0.221079,0.00109178,-0.00803068 beta-lactamase_D129T,beta-lactamase_129,TEM-1,beta-lactamase,P62593,-0.00803068,NO,129,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.816,-3.447,2.631,4.84204,,,B,1.33,-0.69,0.548,,34.97,PAP,-0.818,0.221079,0.00109178,-0.00803068 beta-lactamase_D129W,beta-lactamase_129,TEM-1,beta-lactamase,P62593,-0.00803068,NO,129,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.816,-5.545,4.729,4.84204,,,B,1.33,-0.69,0.548,,34.97,PAP,-0.818,0.221079,0.00109178,-0.00803068 beta-lactamase_D129Y,beta-lactamase_129,TEM-1,beta-lactamase,P62593,-0.00803068,NO,129,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.816,-4.385,3.569,4.84204,,,B,1.33,-0.69,0.548,,34.97,PAP,-0.818,0.221079,0.00109178,-0.00803068 beta-lactamase_E164F,beta-lactamase_164,TEM-1,beta-lactamase,P62593,-0.00803068,NO,164,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-0.948,-4.341,3.393,5.3334,0.011,T,B,1.62,-0.4,1.055,,64.69,HAO,-1.388,0.221079,0.00137286,-0.00803068 beta-lactamase_E164G,beta-lactamase_164,TEM-1,beta-lactamase,P62593,-0.00803068,NO,164,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-0.948,-2.443,1.495,5.3334,0.011,T,B,1.62,-0.4,1.055,,64.69,HAO,-1.388,0.221079,0.00137286,-0.00803068 beta-lactamase_E164N,beta-lactamase_164,TEM-1,beta-lactamase,P62593,-0.00803068,NO,164,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-0.948,-3.497,2.549,5.3334,0.011,T,B,1.62,-0.4,1.055,,64.69,HAO,-1.388,0.221079,0.00137286,-0.00803068 beta-lactamase_E164S,beta-lactamase_164,TEM-1,beta-lactamase,P62593,-0.00803068,NO,164,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-0.948,-3.21,2.262,5.3334,0.011,T,B,1.62,-0.4,1.055,,64.69,HAO,-1.388,0.221079,0.00137286,-0.00803068 beta-lactamase_F64D,beta-lactamase_64,TEM-1,beta-lactamase,P62593,-0.00803068,NO,64,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-0.841,-3.919,3.078,5.70769,0.006,E,B,1.33,-0.95,,,,BHO,-0.892667,0.221079,0.000947691,-0.00803068 beta-lactamase_G234D,beta-lactamase_234,TEM-1,beta-lactamase,P62593,-0.00803068,NO,234,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.62,-3.469,2.849,4.24221,0.023,E,B,0.46,-0.86,,,,POH,-1.25733,0.221079,0.000889577,-0.00803068 beta-lactamase_G234I,beta-lactamase_234,TEM-1,beta-lactamase,P62593,-0.00803068,NO,234,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.62,-4.235,3.615,4.24221,0.023,E,B,0.46,-0.86,,,,POH,-1.25733,0.221079,0.000889577,-0.00803068 beta-lactamase_G234K,beta-lactamase_234,TEM-1,beta-lactamase,P62593,-0.00803068,NO,234,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.62,-3.682,3.062,4.24221,0.023,E,B,0.46,-0.86,,,,POH,-1.25733,0.221079,0.000889577,-0.00803068 beta-lactamase_G234P,beta-lactamase_234,TEM-1,beta-lactamase,P62593,-0.00803068,NO,234,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.62,-3.88,3.26,4.24221,0.023,E,B,0.46,-0.86,,,,POH,-1.25733,0.221079,0.000889577,-0.00803068 beta-lactamase_G234W,beta-lactamase_234,TEM-1,beta-lactamase,P62593,-0.00803068,NO,234,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.62,-5.097,4.477,4.24221,0.023,E,B,0.46,-0.86,,,,POH,-1.25733,0.221079,0.000889577,-0.00803068 beta-lactamase_G242F,beta-lactamase_242,TEM-1,beta-lactamase,P62593,-0.00803068,NO,242,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.319,-4.331,3.012,4.68003,,E,B,0.87,-1.05,1.079,,50,BOH,-1.428,0.221079,0.00452879,-0.00803068 beta-lactamase_G242K,beta-lactamase_242,TEM-1,beta-lactamase,P62593,-0.00803068,NO,242,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.319,-3.521,2.202,4.68003,,E,B,0.87,-1.05,1.079,,50,BOH,-1.428,0.221079,0.00452879,-0.00803068 beta-lactamase_G242W,beta-lactamase_242,TEM-1,beta-lactamase,P62593,-0.00803068,NO,242,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.319,-5.388,4.069,4.68003,,E,B,0.87,-1.05,1.079,,50,BOH,-1.428,0.221079,0.00452879,-0.00803068 beta-lactamase_G248P,beta-lactamase_248,TEM-1,beta-lactamase,P62593,-0.00803068,NO,248,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.794,-4.081,2.287,4.69798,,E,b,0.23,-0.43,1.782,,61.19,HOO,-1.52867,0.221079,0.00428493,-0.00803068 beta-lactamase_G43I,beta-lactamase_43,TEM-1,beta-lactamase,P62593,-0.00803068,NO,43,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.62,-4.235,3.615,5.28886,,E,B,0.77,-0.78,,,,HOH,-1.577,0.221079,0.00120151,-0.00803068 beta-lactamase_G43K,beta-lactamase_43,TEM-1,beta-lactamase,P62593,-0.00803068,NO,43,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.62,-3.682,3.062,5.28886,,E,B,0.77,-0.78,,,,HOH,-1.577,0.221079,0.00120151,-0.00803068 beta-lactamase_G43M,beta-lactamase_43,TEM-1,beta-lactamase,P62593,-0.00803068,NO,43,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.62,-4.93,4.31,5.28886,,E,B,0.77,-0.78,,,,HOH,-1.577,0.221079,0.00120151,-0.00803068 beta-lactamase_G43N,beta-lactamase_43,TEM-1,beta-lactamase,P62593,-0.00803068,NO,43,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.62,-3.448,2.828,5.28886,,E,B,0.77,-0.78,,,,HOH,-1.577,0.221079,0.00120151,-0.00803068 beta-lactamase_I125K,beta-lactamase_125,TEM-1,beta-lactamase,P62593,-0.00803068,NO,125,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.441,-3.825,2.384,5.23481,,H,A,2.82,-0.7,2.301,,63.29,HHP,-1.248,0.221079,0.00383964,-0.00803068 beta-lactamase_I125P,beta-lactamase_125,TEM-1,beta-lactamase,P62593,-0.00803068,NO,125,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.441,-4.116,2.675,5.23481,,H,A,2.82,-0.7,2.301,,63.29,HHP,-1.248,0.221079,0.00383964,-0.00803068 beta-lactamase_I125W,beta-lactamase_125,TEM-1,beta-lactamase,P62593,-0.00803068,NO,125,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.441,-5.341,3.9,5.23481,,H,A,2.82,-0.7,2.301,,63.29,HHP,-1.248,0.221079,0.00383964,-0.00803068 beta-lactamase_I229P,beta-lactamase_229,TEM-1,beta-lactamase,P62593,-0.00803068,NO,229,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.267,-4.079,2.812,5.0911,0.083,E,B,1,-0.76,1.114,,50,HHH,-1.58767,0.221079,0.00477249,-0.00803068 beta-lactamase_I244W,beta-lactamase_244,TEM-1,beta-lactamase,P62593,-0.00803068,NO,244,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.555,-5.375,3.82,5.35885,,E,B,0.01,-0.84,0.379,,77.62,HHH,-1.385,0.221079,0.00605379,-0.00803068 beta-lactamase_I256P,beta-lactamase_256,TEM-1,beta-lactamase,P62593,-0.00803068,NO,256,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.621,-4.177,2.556,5.3196,,E,B,1,-0.84,1.615,,73.08,BHH,-1.80667,0.221079,0.00710634,-0.00803068 beta-lactamase_I259P,beta-lactamase_259,TEM-1,beta-lactamase,P62593,-0.00803068,NO,259,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.522,-4.093,2.571,5.28457,,E,B,1,-0.8,1.24,,64.34,HHH,-1.53267,0.221079,0.0070773,-0.00803068 beta-lactamase_I275P,beta-lactamase_275,TEM-1,beta-lactamase,P62593,-0.00803068,NO,275,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.397,-4.169,2.772,5.3999,0.015,H,A,1,-0.52,0.836,,62.59,PHH,-1.541,0.221079,0.0141984,-0.00803068 beta-lactamase_I275R,beta-lactamase_275,TEM-1,beta-lactamase,P62593,-0.00803068,NO,275,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.397,-4.133,2.736,5.3999,0.015,H,A,1,-0.52,0.836,,62.59,PHH,-1.541,0.221079,0.0141984,-0.00803068 beta-lactamase_I278G,beta-lactamase_278,TEM-1,beta-lactamase,P62593,-0.00803068,NO,278,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.348,-3.791,2.443,5.35127,0.015,H,A,0.77,-0.85,2.718,,63.29,AHO,-1.41833,0.221079,0.0310297,-0.00803068 beta-lactamase_I278H,beta-lactamase_278,TEM-1,beta-lactamase,P62593,-0.00803068,NO,278,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.348,-4.927,3.579,5.35127,0.015,H,A,0.77,-0.85,2.718,,63.29,AHO,-1.41833,0.221079,0.0310297,-0.00803068 beta-lactamase_I278N,beta-lactamase_278,TEM-1,beta-lactamase,P62593,-0.00803068,NO,278,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.348,-4.095,2.747,5.35127,0.015,H,A,0.77,-0.85,2.718,,63.29,AHO,-1.41833,0.221079,0.0310297,-0.00803068 beta-lactamase_I278P,beta-lactamase_278,TEM-1,beta-lactamase,P62593,-0.00803068,NO,278,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.348,-4.11,2.762,5.35127,0.015,H,A,0.77,-0.85,2.718,,63.29,AHO,-1.41833,0.221079,0.0310297,-0.00803068 beta-lactamase_I45P,beta-lactamase_45,TEM-1,beta-lactamase,P62593,-0.00803068,NO,45,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-2.421,-4.091,1.67,5.31505,,E,B,1,-0.3,2.256,,77.62,HHA,-2.30267,0.221079,0.00452842,-0.00803068 beta-lactamase_K232F,beta-lactamase_232,TEM-1,beta-lactamase,P62593,-0.00803068,NO,232,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.012,-4.334,3.322,5.18286,,E,B,2.92,-1.1,1.174,,65.03,ABP,-1.238,0.221079,0.00313441,-0.00803068 beta-lactamase_K232M,beta-lactamase_232,TEM-1,beta-lactamase,P62593,-0.00803068,NO,232,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.012,-4.522,3.51,5.18286,,E,B,2.92,-1.1,1.174,,65.03,ABP,-1.238,0.221079,0.00313441,-0.00803068 beta-lactamase_K232P,beta-lactamase_232,TEM-1,beta-lactamase,P62593,-0.00803068,NO,232,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.012,-3.752,2.74,5.18286,,E,B,2.92,-1.1,1.174,,65.03,ABP,-1.238,0.221079,0.00313441,-0.00803068 beta-lactamase_K232W,beta-lactamase_232,TEM-1,beta-lactamase,P62593,-0.00803068,NO,232,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.012,-5.365,4.353,5.18286,,E,B,2.92,-1.1,1.174,,65.03,ABP,-1.238,0.221079,0.00313441,-0.00803068 beta-lactamase_K71E,beta-lactamase_71,TEM-1,beta-lactamase,P62593,-0.00803068,NO,71,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-0.8,-2.99,2.19,5.15697,,H,A,1.3,-0.99,,,,HBH,-1.209,0.221079,0.00103192,-0.00803068 beta-lactamase_K71I,beta-lactamase_71,TEM-1,beta-lactamase,P62593,-0.00803068,NO,71,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-0.8,-4.01,3.21,5.15697,,H,A,1.3,-0.99,,,,HBH,-1.209,0.221079,0.00103192,-0.00803068 beta-lactamase_K71P,beta-lactamase_71,TEM-1,beta-lactamase,P62593,-0.00803068,NO,71,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-0.8,-3.655,2.855,5.15697,,H,A,1.3,-0.99,,,,HBH,-1.209,0.221079,0.00103192,-0.00803068 beta-lactamase_K71Y,beta-lactamase_71,TEM-1,beta-lactamase,P62593,-0.00803068,NO,71,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-0.8,-4.162,3.362,5.15697,,H,A,1.3,-0.99,,,,HBH,-1.209,0.221079,0.00103192,-0.00803068 beta-lactamase_L120D,beta-lactamase_120,TEM-1,beta-lactamase,P62593,-0.00803068,NO,120,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.044,-4.076,3.032,5.11974,,H,A,1.3,-1.13,1.988,,64.69,AHO,-1.13633,0.221079,0.00143563,-0.00803068 beta-lactamase_L120R,beta-lactamase_120,TEM-1,beta-lactamase,P62593,-0.00803068,NO,120,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.044,-2.871,1.827,5.11974,,H,A,1.3,-1.13,1.988,,64.69,AHO,-1.13633,0.221079,0.00143563,-0.00803068 beta-lactamase_L120W,beta-lactamase_120,TEM-1,beta-lactamase,P62593,-0.00803068,NO,120,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.044,-5.142,4.098,5.11974,,H,A,1.3,-1.13,1.988,,64.69,AHO,-1.13633,0.221079,0.00143563,-0.00803068 beta-lactamase_L136K,beta-lactamase_136,TEM-1,beta-lactamase,P62593,-0.00803068,NO,136,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.232,-3.824,2.592,5.31114,,H,A,2.89,-0.34,1.539,,48.95,HHH,-1.088,0.221079,0.00442304,-0.00803068 beta-lactamase_L136W,beta-lactamase_136,TEM-1,beta-lactamase,P62593,-0.00803068,NO,136,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.232,-5.281,4.049,5.31114,,H,A,2.89,-0.34,1.539,,48.95,HHH,-1.088,0.221079,0.00442304,-0.00803068 beta-lactamase_L136Y,beta-lactamase_136,TEM-1,beta-lactamase,P62593,-0.00803068,NO,136,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.232,-4.051,2.819,5.31114,,H,A,2.89,-0.34,1.539,,48.95,HHH,-1.088,0.221079,0.00442304,-0.00803068 beta-lactamase_L146D,beta-lactamase_146,TEM-1,beta-lactamase,P62593,-0.00803068,NO,146,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.462,-4.108,2.646,5.62483,0.007,H,A,1.3,-0.56,1.953,,64.69,AHP,-1.656,0.221079,0.00474542,-0.00803068 beta-lactamase_L205D,beta-lactamase_205,TEM-1,beta-lactamase,P62593,-0.00803068,NO,205,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.922,-4.118,3.196,5.67023,,H,A,1.3,-0.46,0.678,,42.31,PHH,-1.57767,0.221079,0.00255802,-0.00803068 beta-lactamase_L205K,beta-lactamase_205,TEM-1,beta-lactamase,P62593,-0.00803068,NO,205,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.922,-3.736,2.814,5.67023,,H,A,1.3,-0.46,0.678,,42.31,PHH,-1.57767,0.221079,0.00255802,-0.00803068 beta-lactamase_L74R,beta-lactamase_74,TEM-1,beta-lactamase,P62593,-0.00803068,NO,74,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.296,-3.939,2.643,5.50288,,H,A,1.75,-0.91,1.581,,50,HHO,-1.34933,0.221079,0.00493255,-0.00803068 beta-lactamase_M184D,beta-lactamase_184,TEM-1,beta-lactamase,P62593,-0.00803068,NO,184,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.593,-3.936,2.343,5.39575,,H,A,1.3,-0.87,2.893,,62.94,HHH,-1.41,0.221079,0.00356019,-0.00803068 beta-lactamase_M184P,beta-lactamase_184,TEM-1,beta-lactamase,P62593,-0.00803068,NO,184,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.593,-4.009,2.416,5.39575,,H,A,1.3,-0.87,2.893,,62.94,HHH,-1.41,0.221079,0.00356019,-0.00803068 beta-lactamase_M209R,beta-lactamase_209,TEM-1,beta-lactamase,P62593,-0.00803068,NO,209,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.442,-3.939,2.497,5.44502,,H,A,1.75,-0.97,1.402,,64.69,HHA,-1.52633,0.221079,0.00625021,-0.00803068 beta-lactamase_M66D,beta-lactamase_66,TEM-1,beta-lactamase,P62593,-0.00803068,NO,66,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.362,-4.069,2.707,5.29561,0.013,,A,1.3,-0.7,1.319,,73.08,OHH,-1.49567,0.221079,0.00412876,-0.00803068 beta-lactamase_N130W,beta-lactamase_130,TEM-1,beta-lactamase,P62593,-0.00803068,NO,130,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-0.798,-5.547,4.749,5.26686,0.069,H,A,1.08,-0.74,,,,APP,-0.980667,0.221079,0.000683376,-0.00803068 beta-lactamase_P181F,beta-lactamase_181,TEM-1,beta-lactamase,P62593,-0.00803068,NO,181,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.813,-4.48,3.667,5.14752,,H,A,1.1,-1.14,1.357,,61.54,HOH,-1.795,0.221079,0.000703122,-0.00803068 beta-lactamase_P181Q,beta-lactamase_181,TEM-1,beta-lactamase,P62593,-0.00803068,NO,181,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.813,-3.925,3.112,5.14752,,H,A,1.1,-1.14,1.357,,61.54,HOH,-1.795,0.221079,0.000703122,-0.00803068 beta-lactamase_P181W,beta-lactamase_181,TEM-1,beta-lactamase,P62593,-0.00803068,NO,181,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.813,-5.545,4.732,5.14752,,H,A,1.1,-1.14,1.357,,61.54,HOH,-1.795,0.221079,0.000703122,-0.00803068 beta-lactamase_R159P,beta-lactamase_159,TEM-1,beta-lactamase,P62593,-0.00803068,NO,159,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-0.94,-3.905,2.965,5.64971,0.316,,B,0.68,-0.55,1.172,,64.34,PBH,-1.011,0.221079,0.00108472,-0.00803068 beta-lactamase_R241P,beta-lactamase_241,TEM-1,beta-lactamase,P62593,-0.00803068,NO,241,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.433,-3.939,2.506,5.02621,0.094,E,B,0.68,-0.16,1.327,,50,PBO,-1.42967,0.221079,0.00452736,-0.00803068 beta-lactamase_R255P,beta-lactamase_255,TEM-1,beta-lactamase,P62593,-0.00803068,NO,255,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.266,-4.188,1.922,5.55882,0.141,E,B,0.68,0.38,1.199,,63.99,PBH,-2.00433,0.221079,0.00499612,-0.00803068 beta-lactamase_S128C,beta-lactamase_128,TEM-1,beta-lactamase,P62593,-0.00803068,NO,128,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-0.84,-4.637,3.797,5.37153,0.08,,L,0.73,-0.32,,,,HPA,-1.30233,0.221079,0.00071483,-0.00803068 beta-lactamase_S128D,beta-lactamase_128,TEM-1,beta-lactamase,P62593,-0.00803068,NO,128,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-0.84,-3.244,2.404,5.37153,0.08,,L,0.73,-0.32,,,,HPA,-1.30233,0.221079,0.00071483,-0.00803068 beta-lactamase_S128H,beta-lactamase_128,TEM-1,beta-lactamase,P62593,-0.00803068,NO,128,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-0.84,-4.455,3.615,5.37153,0.08,,L,0.73,-0.32,,,,HPA,-1.30233,0.221079,0.00071483,-0.00803068 beta-lactamase_S128K,beta-lactamase_128,TEM-1,beta-lactamase,P62593,-0.00803068,NO,128,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-0.84,-3.232,2.392,5.37153,0.08,,L,0.73,-0.32,,,,HPA,-1.30233,0.221079,0.00071483,-0.00803068 beta-lactamase_S128L,beta-lactamase_128,TEM-1,beta-lactamase,P62593,-0.00803068,NO,128,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-0.84,-3.358,2.518,5.37153,0.08,,L,0.73,-0.32,,,,HPA,-1.30233,0.221079,0.00071483,-0.00803068 beta-lactamase_S128Q,beta-lactamase_128,TEM-1,beta-lactamase,P62593,-0.00803068,NO,128,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-0.84,-3.674,2.834,5.37153,0.08,,L,0.73,-0.32,,,,HPA,-1.30233,0.221079,0.00071483,-0.00803068 beta-lactamase_S128V,beta-lactamase_128,TEM-1,beta-lactamase,P62593,-0.00803068,NO,128,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-0.84,-3.529,2.689,5.37153,0.08,,L,0.73,-0.32,,,,HPA,-1.30233,0.221079,0.00071483,-0.00803068 beta-lactamase_S128W,beta-lactamase_128,TEM-1,beta-lactamase,P62593,-0.00803068,NO,128,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-0.84,-5.322,4.482,5.37153,0.08,,L,0.73,-0.32,,,,HPA,-1.30233,0.221079,0.00071483,-0.00803068 beta-lactamase_S128Y,beta-lactamase_128,TEM-1,beta-lactamase,P62593,-0.00803068,NO,128,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-0.84,-4.162,3.322,5.37153,0.08,,L,0.73,-0.32,,,,HPA,-1.30233,0.221079,0.00071483,-0.00803068 beta-lactamase_S233D,beta-lactamase_233,TEM-1,beta-lactamase,P62593,-0.00803068,NO,233,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.886,-3.5,1.614,4.98121,0.016,E,B,0.48,-1.01,5.361,,77.62,BPO,-1.17267,0.221079,0.00311415,-0.00803068 beta-lactamase_S68E,beta-lactamase_68,TEM-1,beta-lactamase,P62593,-0.00803068,NO,68,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-0.913,-3.241,2.328,4.94745,0.064,G,A,0.77,-1.03,3.202,,64.69,HPP,-1.37233,0.221079,0.000800065,-0.00803068 beta-lactamase_S68F,beta-lactamase_68,TEM-1,beta-lactamase,P62593,-0.00803068,NO,68,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-0.913,-4.116,3.203,4.94745,0.064,G,A,0.77,-1.03,3.202,,64.69,HPP,-1.37233,0.221079,0.000800065,-0.00803068 beta-lactamase_S68I,beta-lactamase_68,TEM-1,beta-lactamase,P62593,-0.00803068,NO,68,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-0.913,-3.834,2.921,4.94745,0.064,G,A,0.77,-1.03,3.202,,64.69,HPP,-1.37233,0.221079,0.000800065,-0.00803068 beta-lactamase_S68K,beta-lactamase_68,TEM-1,beta-lactamase,P62593,-0.00803068,NO,68,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-0.913,-3.258,2.345,4.94745,0.064,G,A,0.77,-1.03,3.202,,64.69,HPP,-1.37233,0.221079,0.000800065,-0.00803068 beta-lactamase_S68M,beta-lactamase_68,TEM-1,beta-lactamase,P62593,-0.00803068,NO,68,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-0.913,-4.529,3.616,4.94745,0.064,G,A,0.77,-1.03,3.202,,64.69,HPP,-1.37233,0.221079,0.000800065,-0.00803068 beta-lactamase_S68Q,beta-lactamase_68,TEM-1,beta-lactamase,P62593,-0.00803068,NO,68,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-0.913,-3.7,2.787,4.94745,0.064,G,A,0.77,-1.03,3.202,,64.69,HPP,-1.37233,0.221079,0.000800065,-0.00803068 beta-lactamase_S68W,beta-lactamase_68,TEM-1,beta-lactamase,P62593,-0.00803068,NO,68,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-0.913,-5.371,4.458,4.94745,0.064,G,A,0.77,-1.03,3.202,,64.69,HPP,-1.37233,0.221079,0.000800065,-0.00803068 beta-lactamase_S68Y,beta-lactamase_68,TEM-1,beta-lactamase,P62593,-0.00803068,NO,68,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-0.913,-4.188,3.275,4.94745,0.064,G,A,0.77,-1.03,3.202,,64.69,HPP,-1.37233,0.221079,0.000800065,-0.00803068 beta-lactamase_T179F,beta-lactamase_179,TEM-1,beta-lactamase,P62593,-0.00803068,NO,179,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.085,-4.108,3.023,5.07116,,E,B,0.8,-1.38,1.859,,73.08,PPH,-1.557,0.221079,0.00226045,-0.00803068 beta-lactamase_T179W,beta-lactamase_179,TEM-1,beta-lactamase,P62593,-0.00803068,NO,179,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.085,-5.211,4.126,5.07116,,E,B,0.8,-1.38,1.859,,73.08,PPH,-1.557,0.221079,0.00226045,-0.00803068 beta-lactamase_T179Y,beta-lactamase_179,TEM-1,beta-lactamase,P62593,-0.00803068,NO,179,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.085,-4.097,3.012,5.07116,,E,B,0.8,-1.38,1.859,,73.08,PPH,-1.557,0.221079,0.00226045,-0.00803068 beta-lactamase_T69W,beta-lactamase_69,TEM-1,beta-lactamase,P62593,-0.00803068,NO,69,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-0.973,-5.208,4.235,5.16042,,G,A,0.69,-1.24,0.505,,93.01,PPH,-1.01833,0.221079,0.00127498,-0.00803068 beta-lactamase_V257P,beta-lactamase_257,TEM-1,beta-lactamase,P62593,-0.00803068,NO,257,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.533,-4.013,2.48,5.31999,,E,B,0.96,-0.7,1.463,,58.74,HHH,-1.70967,0.221079,0.00756629,-0.00803068 beta-lactamase_V258R,beta-lactamase_258,TEM-1,beta-lactamase,P62593,-0.00803068,NO,258,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.975,-4.002,2.027,5.16083,,E,B,1.64,-1.02,2.124,,67.83,HHH,-1.67667,0.221079,0.007931,-0.00803068 beta-lactamase_V72K,beta-lactamase_72,TEM-1,beta-lactamase,P62593,-0.00803068,NO,72,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.658,-3.754,2.096,5.80324,,H,A,2.78,-1.03,2.964,,65.73,BHH,-1.32167,0.221079,0.00501194,-0.00803068 beta-lactamase_V78P,beta-lactamase_78,TEM-1,beta-lactamase,P62593,-0.00803068,NO,78,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.459,-4.126,2.667,4.79197,,H,A,0.96,-0.47,1.132,,63.64,HHH,-1.17833,0.221079,0.00492501,-0.00803068 beta-lactamase_W227P,beta-lactamase_227,TEM-1,beta-lactamase,P62593,-0.00803068,NO,227,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-0.982,-4.323,3.341,4.86393,0.272,,B,0.99,-0.29,1.37,,74.48,OHH,-1.595,0.221079,0.00226019,-0.00803068 beta-lactamase_Y260P,beta-lactamase_260,TEM-1,beta-lactamase,P62593,-0.00803068,NO,260,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-1.101,-4.218,3.117,5.50878,,E,B,0.73,-1.04,0.865,,60.49,HHP,-1.83433,0.221079,0.00471757,-0.00803068 beta-lactamase_Y260R,beta-lactamase_260,TEM-1,beta-lactamase,P62593,-0.00803068,NO,260,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-1.101,-4.047,2.946,5.50878,,E,B,0.73,-1.04,0.865,,60.49,HHP,-1.83433,0.221079,0.00471757,-0.00803068 beta-lactamase_Y44K,beta-lactamase_44,TEM-1,beta-lactamase,P62593,-0.00803068,NO,44,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-2.547,-3.823,1.276,5.6273,,E,B,2.55,-0.45,2.683,,73.78,OHH,-1.86267,0.221079,0.00426364,-0.00803068 beta-lactamase_Y44P,beta-lactamase_44,TEM-1,beta-lactamase,P62593,-0.00803068,NO,44,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-2.547,-4.12,1.573,5.6273,,E,B,2.55,-0.45,2.683,,73.78,OHH,-1.86267,0.221079,0.00426364,-0.00803068 beta-lactamase_625_I258P,beta-lactamase_625_258,TEM-1,beta-lactamase_625,P62593,-0.00801735,NO,258,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.213352,0.007931,-0.00801735 beta-lactamase_2500_M209T,beta-lactamase_2500_209,TEM-1,beta-lactamase_2500,P62593,-0.00778526,NO,209,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.442,-3.52,2.078,,,H,A,0.55,-0.97,3.229,,64.69,HHA,-1.52633,0.361275,0.00625021,-0.00778526 kka2_1:1_T187P,kka2_1:1_187,Kka2,kka2_1:1,P00552,-0.00762488,NO,187,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.273,-3.887,2.614,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.520039,0.00693073,-0.00762488 beta-lactamase_G242L,beta-lactamase_242,TEM-1,beta-lactamase,P62593,-0.00735656,NO,242,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.319,-3.664,2.345,4.68003,,E,B,0.87,-1.05,1.079,,50,BOH,-1.428,0.221079,0.00452879,-0.00735656 kka2_1:2_G213I,kka2_1:2_213,Kka2,kka2_1:2,P00552,-0.00732523,NO,213,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.596,-4.264,3.668,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.295029,0.00187654,-0.00732523 kka2_1:8_G189N,kka2_1:8_189,Kka2,kka2_1:8,P00552,-0.00706807,NO,189,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.596,-3.476,2.88,,0.034,S,l,0.75,-0.99,,,,BOA,-0.739,0.100394,0.00253688,-0.00706807 kka2_1:8_G189N,kka2_1:8_189,Kka2,kka2_1:8,P00552,-0.00706807,NO,189,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.596,-3.476,2.88,,0.034,S,l,0.75,-0.99,,,,BOA,-0.739,0.100394,0.00253688,-0.00706807 beta-lactamase_39_D129Y,beta-lactamase_39_129,TEM-1,beta-lactamase_39,P62593,-0.00701533,NO,129,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.816,-4.385,3.569,,,,B,0.75,-0.69,0.56,,34.97,PAP,-0.818,0.0495842,0.00109178,-0.00701533 beta-lactamase_625_A132Y,beta-lactamase_625_132,TEM-1,beta-lactamase_625,P62593,-0.00693651,NO,132,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.9,-4.186,3.286,,,H,A,0.46,-0.93,0.316,,64.69,PHH,-1.138,0.213352,0.000962524,-0.00693651 beta-lactamase_L73R,beta-lactamase_73,TEM-1,beta-lactamase,P62593,-0.00680898,NO,73,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.507,-4.144,2.637,5.84139,,H,A,1.75,-0.64,2.09,,67.83,HHH,-1.487,0.221079,0.00488983,-0.00680898 beta-lactamase_G242P,beta-lactamase_242,TEM-1,beta-lactamase,P62593,-0.00672764,NO,242,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.319,-3.918,2.599,4.68003,,E,B,0.87,-1.05,1.079,,50,BOH,-1.428,0.221079,0.00452879,-0.00672764 kka2_1:8_L259Y,kka2_1:8_259,Kka2,kka2_1:8,P00552,-0.00671525,NO,259,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.088,-4.087,2.999,,0.036,H,A,1.59,-0.15,1.83,,48.48,BHH,-1.15167,0.100394,0.0206964,-0.00671525 kka2_1:8_L259Y,kka2_1:8_259,Kka2,kka2_1:8,P00552,-0.00671525,NO,259,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.088,-4.087,2.999,,0.036,H,A,1.59,-0.15,1.83,,48.48,BHH,-1.15167,0.100394,0.0206964,-0.00671525 beta-lactamase_625_M184N,beta-lactamase_625_184,TEM-1,beta-lactamase_625,P62593,-0.00656797,NO,184,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.593,-4.028,2.435,,,H,A,0.55,-0.87,2.765,,62.94,HHH,-1.41,0.213352,0.00356019,-0.00656797 beta-lactamase_I243R,beta-lactamase_243,TEM-1,beta-lactamase,P62593,-0.00644583,NO,243,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.532,-4.053,2.521,5.26886,,E,B,1.68,-1.24,2.289,,50,OHH,-1.46867,0.221079,0.00464034,-0.00644583 beta-lactamase_T179Q,beta-lactamase_179,TEM-1,beta-lactamase,P62593,-0.00642856,NO,179,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.085,-3.906,2.821,5.07116,,E,B,0.8,-1.38,1.859,,73.08,PPH,-1.557,0.221079,0.00226045,-0.00642856 beta-lactamase_K232L,beta-lactamase_232,TEM-1,beta-lactamase,P62593,-0.00625364,NO,232,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.012,-3.401,2.389,5.18286,,E,B,2.92,-1.1,1.174,,65.03,ABP,-1.238,0.221079,0.00313441,-0.00625364 beta-lactamase_D129L,beta-lactamase_129,TEM-1,beta-lactamase,P62593,-0.00618668,NO,129,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.816,-3.806,2.99,4.84204,,,B,1.33,-0.69,0.548,,34.97,PAP,-0.818,0.221079,0.00109178,-0.00618668 beta-lactamase_2500_V31H,beta-lactamase_2500_31,TEM-1,beta-lactamase_2500,P62593,-0.00608753,NO,31,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.822,-4.968,3.146,,,H,A,0.44,-0.46,0.955,,73.78,BHB,-2.03767,0.361275,0.00478065,-0.00608753 beta-lactamase_A245P,beta-lactamase_245,TEM-1,beta-lactamase,P62593,-0.00603613,NO,245,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.068,-3.786,2.718,4.78972,,E,B,0.17,-0.92,0.831,,64.69,HHH,-1.58133,0.221079,0.00391032,-0.00603613 beta-lactamase_D129V,beta-lactamase_129,TEM-1,beta-lactamase,P62593,-0.00603613,NO,129,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.816,-3.751,2.935,4.84204,,,B,1.33,-0.69,0.548,,34.97,PAP,-0.818,0.221079,0.00109178,-0.00603613 beta-lactamase_A245E,beta-lactamase_245,TEM-1,beta-lactamase,P62593,-0.00599467,NO,245,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.068,-3.547,2.479,4.78972,,E,B,0.17,-0.92,0.831,,64.69,HHH,-1.58133,0.221079,0.00391032,-0.00599467 beta-lactamase_D129H,beta-lactamase_129,TEM-1,beta-lactamase,P62593,-0.00590611,NO,129,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.816,-4.453,3.637,4.84204,,,B,1.33,-0.69,0.548,,34.97,PAP,-0.818,0.221079,0.00109178,-0.00590611 beta-lactamase_D129R,beta-lactamase_129,TEM-1,beta-lactamase,P62593,-0.0057839,NO,129,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.816,-3.896,3.08,4.84204,,,B,1.33,-0.69,0.548,,34.97,PAP,-0.818,0.221079,0.00109178,-0.0057839 beta-lactamase_P181Y,beta-lactamase_181,TEM-1,beta-lactamase,P62593,-0.00575786,NO,181,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.813,-4.385,3.572,5.14752,,H,A,1.1,-1.14,1.357,,61.54,HOH,-1.795,0.221079,0.000703122,-0.00575786 beta-lactamase_625_L136N,beta-lactamase_625_136,TEM-1,beta-lactamase_625,P62593,-0.00574343,NO,136,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.232,-4.217,2.985,,,H,A,0.55,-0.34,0.336,,48.95,HHH,-1.088,0.213352,0.00442304,-0.00574343 beta-lactamase_0_M67C,beta-lactamase_0_67,TEM-1,beta-lactamase_0,P62593,-0.00542675,NO,67,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-2.231,-2.364,0.133,,0.006,G,P,0.55,-0.81,24.165,24.165,65.03,HHP,-1.502,0.0500837,0.00409753,-0.00542675 beta-lactamase_625_L136Y,beta-lactamase_625_136,TEM-1,beta-lactamase_625,P62593,-0.00538854,NO,136,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.232,-4.051,2.819,,,H,A,0.55,-0.34,0.336,,48.95,HHH,-1.088,0.213352,0.00442304,-0.00538854 beta-lactamase_39_G243L,beta-lactamase_39_243,TEM-1,beta-lactamase_39,P62593,-0.00524773,NO,243,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.0495842,0.00464034,-0.00524773 beta-lactamase_I278R,beta-lactamase_278,TEM-1,beta-lactamase,P62593,-0.00523839,NO,278,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.348,-2.966,1.618,5.35127,0.015,H,A,0.77,-0.85,2.718,,63.29,AHO,-1.41833,0.221079,0.0310297,-0.00523839 kka2_1:1_T73P,kka2_1:1_73,Kka2,kka2_1:1,P00552,-0.00523422,NO,73,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.51,-4.057,1.547,,0.309,H,A,0.22,0.35,4.126,,56.06,PPO,-2.02333,0.520039,0.00628605,-0.00523422 beta-lactamase_L191P,beta-lactamase_191,TEM-1,beta-lactamase,P62593,-0.00515612,NO,191,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.087,-4.09,3.003,5.72226,,H,A,1.07,0.09,1.23,,63.29,BHH,-1.445,0.221079,0.00263549,-0.00515612 beta-lactamase_39_I261R,beta-lactamase_39_261,TEM-1,beta-lactamase_39,P62593,-0.00512445,NO,261,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.0495842,0.0123091,-0.00512445 beta-lactamase_T158R,beta-lactamase_158,TEM-1,beta-lactamase,P62593,-0.00506909,NO,158,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.116,-3.803,2.687,5.32011,0.036,,B,0.98,-0.85,2.755,,69.58,HPB,-1.269,0.221079,0.00341825,-0.00506909 beta-lactamase_A245K,beta-lactamase_245,TEM-1,beta-lactamase,P62593,-0.00497646,NO,245,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.068,-3.564,2.496,4.78972,,E,B,0.17,-0.92,0.831,,64.69,HHH,-1.58133,0.221079,0.00391032,-0.00497646 beta-lactamase_L137P,beta-lactamase_137,TEM-1,beta-lactamase,P62593,-0.0049116,NO,137,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.03,-4.134,3.104,5.20117,,H,A,1.07,-0.38,0.674,,42.31,HHP,-1.58933,0.221079,0.00278599,-0.0049116 beta-lactamase_I259R,beta-lactamase_259,TEM-1,beta-lactamase,P62593,-0.0048781,NO,259,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.522,-4.154,2.632,5.28457,,E,B,1,-0.8,1.24,,64.34,HHH,-1.53267,0.221079,0.0070773,-0.0048781 beta-lactamase_A245R,beta-lactamase_245,TEM-1,beta-lactamase,P62593,-0.00484378,NO,245,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.068,-3.855,2.787,4.78972,,E,B,0.17,-0.92,0.831,,64.69,HHH,-1.58133,0.221079,0.00391032,-0.00484378 beta-lactamase_A124R,beta-lactamase_124,TEM-1,beta-lactamase,P62593,-0.00477301,NO,124,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.181,-3.827,2.646,4.58507,,H,A,0.58,-0.9,2.273,,64.34,HHH,-1.152,0.221079,0.00481399,-0.00477301 beta-lactamase_A132R,beta-lactamase_132,TEM-1,beta-lactamase,P62593,-0.00477301,NO,132,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.9,-3.795,2.895,4.58504,,H,A,2.34,-0.93,2.217,,64.69,PHH,-1.138,0.221079,0.000962524,-0.00477301 beta-lactamase_I243P,beta-lactamase_243,TEM-1,beta-lactamase,P62593,-0.00477301,NO,243,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.532,-4.057,2.525,5.26886,,E,B,1.68,-1.24,2.289,,50,OHH,-1.46867,0.221079,0.00464034,-0.00477301 beta-lactamase_L47P,beta-lactamase_47,TEM-1,beta-lactamase,P62593,-0.00477301,NO,47,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.876,-4.153,2.277,5.27297,0.007,E,B,1.07,0.2,1.244,,67.83,AHA,-1.639,0.221079,0.00439844,-0.00477301 beta-lactamase_G242Y,beta-lactamase_242,TEM-1,beta-lactamase,P62593,-0.00447672,NO,242,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.319,-4.347,3.028,4.68003,,E,B,0.87,-1.05,1.079,,50,BOH,-1.428,0.221079,0.00452879,-0.00447672 beta-lactamase_T179E,beta-lactamase_179,TEM-1,beta-lactamase,P62593,-0.00447672,NO,179,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.085,-3.446,2.361,5.07116,,E,B,0.8,-1.38,1.859,,73.08,PPH,-1.557,0.221079,0.00226045,-0.00447672 beta-lactamase_G43E,beta-lactamase_43,TEM-1,beta-lactamase,P62593,-0.00441093,NO,43,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.62,-3.665,3.045,5.28886,,E,B,0.77,-0.78,,,,HOH,-1.577,0.221079,0.00120151,-0.00441093 beta-lactamase_S128R,beta-lactamase_128,TEM-1,beta-lactamase,P62593,-0.00434268,NO,128,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-0.84,-3.708,2.868,5.37153,0.08,,L,0.73,-0.32,,,,HPA,-1.30233,0.221079,0.00071483,-0.00434268 kka2_1:4_L123Q,kka2_1:4_123,Kka2,kka2_1:4,P00552,-0.00431244,NO,123,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.888,-4.152,3.264,,0.007,H,A,0.55,-0.4,1.447,,48.86,BHB,-1.301,0.168804,0.00325188,-0.00431244 beta-lactamase_G43R,beta-lactamase_43,TEM-1,beta-lactamase,P62593,-0.00427167,NO,43,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.62,-3.933,3.313,5.28886,,E,B,0.77,-0.78,,,,HOH,-1.577,0.221079,0.00120151,-0.00427167 beta-lactamase_2500_I125W,beta-lactamase_2500_125,TEM-1,beta-lactamase_2500,P62593,-0.00418016,NO,125,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.441,-5.341,3.9,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.361275,0.00383964,-0.00418016 beta-lactamase_2500_L160R,beta-lactamase_2500_160,TEM-1,beta-lactamase_2500,P62593,-0.00413174,NO,160,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.977,-4.03,3.053,,0.022,,B,0.55,-0.6,0.895,,44.41,BHA,-0.936,0.361275,0.00193775,-0.00413174 beta-lactamase_A230D,beta-lactamase_230,TEM-1,beta-lactamase,P62593,-0.00404169,NO,230,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.154,-3.645,2.491,4.54336,0.01,E,B,0.75,-1.17,1.97,,50,HHA,-1.079,0.221079,0.00516841,-0.00404169 beta-lactamase_625_L205Y,beta-lactamase_625_205,TEM-1,beta-lactamase_625,P62593,-0.00399172,NO,205,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.922,-3.727,2.805,,,H,A,0.55,-0.46,3.782,,42.31,PHH,-1.57767,0.213352,0.00255802,-0.00399172 beta-lactamase_T179H,beta-lactamase_179,TEM-1,beta-lactamase,P62593,-0.00395848,NO,179,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.085,-2.971,1.886,5.07116,,E,B,0.8,-1.38,1.859,,73.08,PPH,-1.557,0.221079,0.00226045,-0.00395848 kka2_1:4_G30L,kka2_1:4_30,Kka2,kka2_1:4,P00552,-0.00395671,NO,30,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.596,-3.836,3.24,,0.54,S,g,0.29,3.76,,,,HOO,-1.51133,0.168804,0.00159208,-0.00395671 beta-lactamase_625_Y44R,beta-lactamase_625_44,TEM-1,beta-lactamase_625,P62593,-0.00386025,NO,44,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-2.547,-4.123,1.576,,,E,B,0.21,-0.45,2.371,,73.78,OHH,-1.86267,0.213352,0.00426364,-0.00386025 beta-lactamase_S68V,beta-lactamase_68,TEM-1,beta-lactamase,P62593,-0.00378149,NO,68,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-0.913,-3.578,2.665,4.94745,0.064,G,A,0.77,-1.03,3.202,,64.69,HPP,-1.37233,0.221079,0.000800065,-0.00378149 beta-lactamase_V72R,beta-lactamase_72,TEM-1,beta-lactamase,P62593,-0.00378149,NO,72,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.658,-4.097,2.439,5.80324,,H,A,2.78,-1.03,2.964,,65.73,BHH,-1.32167,0.221079,0.00501194,-0.00378149 beta-lactamase_A245D,beta-lactamase_245,TEM-1,beta-lactamase,P62593,-0.00358829,NO,245,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.068,-3.693,2.625,4.78972,,E,B,0.17,-0.92,0.831,,64.69,HHH,-1.58133,0.221079,0.00391032,-0.00358829 beta-lactamase_S68D,beta-lactamase_68,TEM-1,beta-lactamase,P62593,-0.00358829,NO,68,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-0.913,-3.241,2.328,4.94745,0.064,G,A,0.77,-1.03,3.202,,64.69,HPP,-1.37233,0.221079,0.000800065,-0.00358829 kka2_1:8_L212E,kka2_1:8_212,Kka2,kka2_1:8,P00552,-0.00355678,NO,212,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.904,-3.881,2.977,,,,B,1.59,-0.78,1.708,,42.42,BHO,-0.799667,0.100394,0.0031426,-0.00355678 kka2_1:8_L212E,kka2_1:8_212,Kka2,kka2_1:8,P00552,-0.00355678,NO,212,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.904,-3.881,2.977,,,,B,1.59,-0.78,1.708,,42.42,BHO,-0.799667,0.100394,0.0031426,-0.00355678 beta-lactamase_G242I,beta-lactamase_242,TEM-1,beta-lactamase,P62593,-0.00348498,NO,242,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.319,-4.091,2.772,4.68003,,E,B,0.87,-1.05,1.079,,50,BOH,-1.428,0.221079,0.00452879,-0.00348498 beta-lactamase_G43D,beta-lactamase_43,TEM-1,beta-lactamase,P62593,-0.00337682,NO,43,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.62,-3.469,2.849,5.28886,,E,B,0.77,-0.78,,,,HOH,-1.577,0.221079,0.00120151,-0.00337682 beta-lactamase_W227K,beta-lactamase_227,TEM-1,beta-lactamase,P62593,-0.00337682,NO,227,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-0.982,-3.931,2.949,4.86393,0.272,,B,0.99,-0.29,1.37,,74.48,OHH,-1.595,0.221079,0.00226019,-0.00337682 kka2_1:2_Q136Y,kka2_1:2_136,Kka2,kka2_1:2,P00552,-0.00327913,NO,136,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-3.021,-4.291,1.27,,0.331,,b,0.4,0.96,2.726,,92.05,BPH,-2.16933,0.295029,0.00624149,-0.00327913 Pab1_F168P,Pab1_168,Pab1,Pab1,P04147,-0.00325718,NO,168,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.269,-4.14,2.871,,,,,,,0.789,,56.33,OHO,-1.10033,0.175299,0.00064061,-0.00325718 beta-lactamase_L136D,beta-lactamase_136,TEM-1,beta-lactamase,P62593,-0.00314403,NO,136,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.232,-4.137,2.905,5.31114,,H,A,2.89,-0.34,1.539,,48.95,HHH,-1.088,0.221079,0.00442304,-0.00314403 beta-lactamase_L136P,beta-lactamase_136,TEM-1,beta-lactamase,P62593,-0.00308214,NO,136,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.232,-4.152,2.92,5.31114,,H,A,2.89,-0.34,1.539,,48.95,HHH,-1.088,0.221079,0.00442304,-0.00308214 beta-lactamase_156_T179E,beta-lactamase_156_179,TEM-1,beta-lactamase_156,P62593,-0.00303663,NO,179,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.085,-3.446,2.361,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.111618,0.00226045,-0.00303663 beta-lactamase_625_K232V,beta-lactamase_625_232,TEM-1,beta-lactamase_625,P62593,-0.00301892,NO,232,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.012,-3.626,2.614,,,E,B,2.34,-1.1,1.992,,65.03,ABP,-1.238,0.213352,0.00313441,-0.00301892 beta-lactamase_2500_E35P,beta-lactamase_2500_35,TEM-1,beta-lactamase_2500,P62593,-0.00296796,NO,35,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-0.869,-3.68,2.811,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.361275,0.00174441,-0.00296796 beta-lactamase_2500_F64A,beta-lactamase_2500_64,TEM-1,beta-lactamase_2500,P62593,-0.00293384,NO,64,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-0.841,-3.303,2.462,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.361275,0.000947691,-0.00293384 beta-lactamase_L247K,beta-lactamase_247,TEM-1,beta-lactamase,P62593,-0.00288678,NO,247,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.48,-3.822,2.342,5.28771,0.007,E,B,2.89,-0.72,2.951,,63.99,HHO,-1.79833,0.221079,0.00611275,-0.00288678 beta-lactamase_T158K,beta-lactamase_158,TEM-1,beta-lactamase,P62593,-0.00288678,NO,158,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.116,-3.466,2.35,5.32011,0.036,,B,0.98,-0.85,2.755,,69.58,HPB,-1.269,0.221079,0.00341825,-0.00288678 beta-lactamase_V78R,beta-lactamase_78,TEM-1,beta-lactamase,P62593,-0.0027951,NO,78,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.459,-4.181,2.722,4.79197,,H,A,0.96,-0.47,1.132,,63.64,HHH,-1.17833,0.221079,0.00492501,-0.0027951 beta-lactamase_A185D,beta-lactamase_185,TEM-1,beta-lactamase,P62593,-0.00260112,NO,185,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.406,-3.867,2.461,4.89877,,H,A,2.34,-1.02,2.999,,65.03,HHP,-1.84033,0.221079,0.00467449,-0.00260112 beta-lactamase_S68T,beta-lactamase_68,TEM-1,beta-lactamase,P62593,-0.00260112,NO,68,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-0.913,-3.02,2.107,4.94745,0.064,G,A,0.77,-1.03,3.202,,64.69,HPP,-1.37233,0.221079,0.000800065,-0.00260112 kka2_1:4_Y257K,kka2_1:4_257,Kka2,kka2_1:4,P00552,-0.00248182,NO,257,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-1.064,-3.837,2.773,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.168804,0.0148191,-0.00248182 beta-lactamase_L135P,beta-lactamase_135,TEM-1,beta-lactamase,P62593,-0.00244587,NO,135,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.002,-4.134,3.132,5.28497,0.117,H,A,1.07,-0.58,0.697,,43.71,PHH,-1.03767,0.221079,0.00244423,-0.00244587 beta-lactamase_L188P,beta-lactamase_188,TEM-1,beta-lactamase,P62593,-0.00244587,NO,188,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.166,-4.109,2.943,5.55434,,H,A,1.07,-0.3,1.574,,60.14,PHB,-1.47033,0.221079,0.00295687,-0.00244587 beta-lactamase_A185E,beta-lactamase_185,TEM-1,beta-lactamase,P62593,-0.00228168,NO,185,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.406,-3.679,2.273,4.89877,,H,A,2.34,-1.02,2.999,,65.03,HHP,-1.84033,0.221079,0.00467449,-0.00228168 beta-lactamase_T179N,beta-lactamase_179,TEM-1,beta-lactamase,P62593,-0.00228168,NO,179,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.085,-3.487,2.402,5.07116,,E,B,0.8,-1.38,1.859,,73.08,PPH,-1.557,0.221079,0.00226045,-0.00228168 beta-lactamase_2500_E164W,beta-lactamase_2500_164,TEM-1,beta-lactamase_2500,P62593,-0.00213951,NO,164,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-0.948,-5.346,4.398,,0.011,T,B,1.04,-0.4,0.352,,64.69,HAO,-1.388,0.361275,0.00137286,-0.00213951 beta-lactamase_T179K,beta-lactamase_179,TEM-1,beta-lactamase,P62593,-0.00201641,NO,179,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.085,-3.486,2.401,5.07116,,E,B,0.8,-1.38,1.859,,73.08,PPH,-1.557,0.221079,0.00226045,-0.00201641 kka2_1:2_T187K,kka2_1:2_187,Kka2,kka2_1:2,P00552,-0.00199565,NO,187,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.273,-3.655,2.382,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.295029,0.00693073,-0.00199565 beta-lactamase_39_K71L,beta-lactamase_39_71,TEM-1,beta-lactamase_39,P62593,-0.00194538,NO,71,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-0.8,-3.358,2.558,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.0495842,0.00103192,-0.00194538 beta-lactamase_P181D,beta-lactamase_181,TEM-1,beta-lactamase,P62593,-0.00192236,NO,181,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.813,-3.518,2.705,5.14752,,H,A,1.1,-1.14,1.357,,61.54,HOH,-1.795,0.221079,0.000703122,-0.00192236 kka2_1:2_V75P,kka2_1:2_75,Kka2,kka2_1:2,P00552,-0.00189802,NO,75,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-2.06,-4.189,2.129,,0.042,.,B,0.44,-0.2,2.815,,71.59,OHO,-1.563,0.295029,0.00693733,-0.00189802 beta-lactamase_2500_K71G,beta-lactamase_2500_71,TEM-1,beta-lactamase_2500,P62593,-0.00185706,NO,71,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-0.8,-3.358,2.558,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.361275,0.00103192,-0.00185706 beta-lactamase_S68A,beta-lactamase_68,TEM-1,beta-lactamase,P62593,-0.00172537,NO,68,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-0.913,-2.711,1.798,4.94745,0.064,G,A,0.77,-1.03,3.202,,64.69,HPP,-1.37233,0.221079,0.000800065,-0.00172537 beta-lactamase_I125R,beta-lactamase_125,TEM-1,beta-lactamase,P62593,-0.00168435,NO,125,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.441,-4.126,2.685,5.23481,,H,A,2.82,-0.7,2.301,,63.29,HHP,-1.248,0.221079,0.00383964,-0.00168435 beta-lactamase_C75W,beta-lactamase_75,TEM-1,beta-lactamase,P62593,-0.00151521,NO,75,C,W,CW,Special,Hydrophobic,5.07,5.89,0.82,215,121,204,83,108.5,227.8,119.3,-1.245,-5.246,4.001,4.88171,,H,A,0.25,-0.87,0.876,,50,HOO,-1.24333,0.221079,0.0034616,-0.00151521 beta-lactamase_E164A,beta-lactamase_164,TEM-1,beta-lactamase,P62593,-0.00151521,NO,164,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-0.948,-3.102,2.154,5.3334,0.011,T,B,1.62,-0.4,1.055,,64.69,HAO,-1.388,0.221079,0.00137286,-0.00151521 beta-lactamase_I259K,beta-lactamase_259,TEM-1,beta-lactamase,P62593,-0.00151521,NO,259,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.522,-3.829,2.307,5.28457,,E,B,1,-0.8,1.24,,64.34,HHH,-1.53267,0.221079,0.0070773,-0.00151521 beta-lactamase_M67P,beta-lactamase_67,TEM-1,beta-lactamase,P62593,-0.00151521,NO,67,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-2.231,-4.072,1.841,4.9618,0.006,G,P,1.07,-0.81,1.463,,65.03,HHP,-1.502,0.221079,0.00409753,-0.00151521 beta-lactamase_39_I258K,beta-lactamase_39_258,TEM-1,beta-lactamase_39,P62593,-0.00144454,NO,258,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.0495842,0.007931,-0.00144454 beta-lactamase_C75R,beta-lactamase_75,TEM-1,beta-lactamase,P62593,-0.00129049,NO,75,C,R,CR,Special,PositiveCharge,5.07,6.34148,1.27148,180,121,174,53,108.5,173.4,64.9,-1.245,-4.065,2.82,4.88171,,H,A,0.25,-0.87,0.876,,50,HOO,-1.24333,0.221079,0.0034616,-0.00129049 beta-lactamase_156_T179D,beta-lactamase_156_179,TEM-1,beta-lactamase_156,P62593,-0.00120746,NO,179,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.085,-3.517,2.432,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.111618,0.00226045,-0.00120746 beta-lactamase_I244R,beta-lactamase_244,TEM-1,beta-lactamase,P62593,-0.00104967,NO,244,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.555,-4.183,2.628,5.35885,,E,B,0.01,-0.84,0.379,,77.62,HHH,-1.385,0.221079,0.00605379,-0.00104967 beta-lactamase_L205R,beta-lactamase_205,TEM-1,beta-lactamase,P62593,-0.00104967,NO,205,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.922,-3.987,3.065,5.67023,,H,A,1.3,-0.46,0.678,,42.31,PHH,-1.57767,0.221079,0.00255802,-0.00104967 kka2_1:1_V75F,kka2_1:1_75,Kka2,kka2_1:1,P00552,-0.00104422,NO,75,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-2.06,-2.827,0.767,,0.042,.,B,0.44,-0.2,2.815,,71.59,OHO,-1.563,0.520039,0.00693733,-0.00104422 beta-lactamase_P181R,beta-lactamase_181,TEM-1,beta-lactamase,P62593,-0.000965616,NO,181,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.813,-3.93,3.117,5.14752,,H,A,1.1,-1.14,1.357,,61.54,HOH,-1.795,0.221079,0.000703122,-0.000965616 beta-lactamase_S68R,beta-lactamase_68,TEM-1,beta-lactamase,P62593,-0.000904343,NO,68,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-0.913,-3.705,2.792,4.94745,0.064,G,A,0.77,-1.03,3.202,,64.69,HPP,-1.37233,0.221079,0.000800065,-0.000904343 PSD95pdz3_F325P,PSD95pdz3_325,PSD95pdz3,PSD95pdz3,P31016,-0.000810115,NO,325,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.524,-4.011,2.487,5.50654,,,,,12.7236,,,,OHP,-1.314,0.0758425,0.00102273,-0.000810115 beta-lactamase_A133R,beta-lactamase_133,TEM-1,beta-lactamase,P62593,-0.000791216,NO,133,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.186,-3.865,2.679,4.86423,,H,A,0.55,-0.86,2.649,,67.83,HHP,-0.988333,0.221079,0.00468022,-0.000791216 beta-lactamase_T179R,beta-lactamase_179,TEM-1,beta-lactamase,P62593,-0.000770438,NO,179,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.085,-3.749,2.664,5.07116,,E,B,0.8,-1.38,1.859,,73.08,PPH,-1.557,0.221079,0.00226045,-0.000770438 kka2_1:1_D190Q,kka2_1:1_190,Kka2,kka2_1:1,P00552,-0.000741032,NO,190,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.708,-3.703,2.995,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.520039,0.00247989,-0.000741032 beta-lactamase_156_E164C,beta-lactamase_156_164,TEM-1,beta-lactamase_156,P62593,-0.00069983,NO,164,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-0.948,-5.311,4.363,,0.011,T,B,1.04,-0.4,3.445,,64.69,HAO,-1.388,0.111618,0.00137286,-0.00069983 beta-lactamase_156_A132I,beta-lactamase_156_132,TEM-1,beta-lactamase_156,P62593,-0.000565415,NO,132,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.9,-3.489,2.589,,,H,A,0.46,-0.93,10.621,,64.69,PHH,-1.138,0.111618,0.000962524,-0.000565415 beta-lactamase_I244P,beta-lactamase_244,TEM-1,beta-lactamase,P62593,-0.000409321,NO,244,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.555,-4.01,2.455,5.35885,,E,B,0.01,-0.84,0.379,,77.62,HHH,-1.385,0.221079,0.00605379,-0.000409321 kka2_1:2_P76W,kka2_1:2_76,Kka2,kka2_1:2,P00552,-0.000403025,NO,76,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.449,-5.603,4.154,,0.331,.,B,0.52,-0.41,0.345,,63.64,HOO,-1.662,0.295029,0.00625685,-0.000403025 beta-lactamase_S68L,beta-lactamase_68,TEM-1,beta-lactamase,P62593,-0.000315053,NO,68,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-0.913,-3.407,2.494,4.94745,0.064,G,A,0.77,-1.03,3.202,,64.69,HPP,-1.37233,0.221079,0.000800065,-0.000315053 kka2_1:4_L259F,kka2_1:4_259,Kka2,kka2_1:4,P00552,-0.000283396,NO,259,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.088,-3.817,2.729,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.168804,0.0206964,-0.000283396 beta-lactamase_D129A,beta-lactamase_129,TEM-1,beta-lactamase,P62593,-0.000256467,NO,129,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.816,-3.3,2.484,4.84204,,,B,1.33,-0.69,0.548,,34.97,PAP,-0.818,0.221079,0.00109178,-0.000256467 beta-lactamase_39_K232F,beta-lactamase_39_232,TEM-1,beta-lactamase_39,P62593,-0.000233556,NO,232,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.012,-4.334,3.322,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.0495842,0.00313441,-0.000233556 beta-lactamase_2500_L146P,beta-lactamase_2500_146,TEM-1,beta-lactamase_2500,P62593,-7.16E-05,NO,146,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.462,-4.216,2.754,,0.007,H,A,0.55,-0.56,1.578,,64.69,AHP,-1.656,0.361275,0.00474542,-7.16E-05 kka2_1:4_L193I,kka2_1:4_193,Kka2,kka2_1:4,P00552,-5.73E-05,NO,193,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.983,-3.143,2.16,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.168804,0.00480179,-5.73E-05 beta-lactamase_I244D,beta-lactamase_244,TEM-1,beta-lactamase,P62593,-3.44E-05,NO,244,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.555,-3.943,2.388,5.35885,,E,B,0.01,-0.84,0.379,,77.62,HHH,-1.385,0.221079,0.00605379,-3.44E-05 kka2_1:2_A78I,kka2_1:2_78,Kka2,kka2_1:2,P00552,-2.71E-05,NO,78,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.744,-3.934,2.19,,0.078,.,B,0.46,-0.53,0.206,,56.06,OHH,-1.863,0.295029,0.00457299,-2.71E-05 gb1_E253A,gb1_253,gb1,gb1,P06654,0,NO,253,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.71,-2.889,1.179,,,,,,,0.529,,11.83,HAB,-1.54433,0.177985,0.00141452,0 gb1_E253F,gb1_253,gb1,gb1,P06654,0,NO,253,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.71,-3.71,2,,,,,,,0.529,,11.83,HAB,-1.54433,0.177985,0.00141452,0 gb1_E253K,gb1_253,gb1,gb1,P06654,0,NO,253,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.71,-3.099,1.389,,,,,,,0.529,,11.83,HAB,-1.54433,0.177985,0.00141452,0 gb1_E253L,gb1_253,gb1,gb1,P06654,0,NO,253,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.71,-1.652,-0.058,,,,,,,0.529,,11.83,HAB,-1.54433,0.177985,0.00141452,0 gb1_E253M,gb1_253,gb1,gb1,P06654,0,NO,253,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.71,-3.968,2.258,,,,,,,0.529,,11.83,HAB,-1.54433,0.177985,0.00141452,0 gb1_E253Q,gb1_253,gb1,gb1,P06654,0,NO,253,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.71,-3.387,1.677,,,,,,,0.529,,11.83,HAB,-1.54433,0.177985,0.00141452,0 gb1_E253R,gb1_253,gb1,gb1,P06654,0,NO,253,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.71,-3.494,1.784,,,,,,,0.529,,11.83,HAB,-1.54433,0.177985,0.00141452,0 gb1_E253S,gb1_253,gb1,gb1,P06654,0,NO,253,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.71,-3.172,1.462,,,,,,,0.529,,11.83,HAB,-1.54433,0.177985,0.00141452,0 gb1_E253W,gb1_253,gb1,gb1,P06654,0,NO,253,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.71,-5.015,3.305,,,,,,,0.529,,11.83,HAB,-1.54433,0.177985,0.00141452,0 gb1_K257H,gb1_257,gb1,gb1,P06654,0,NO,257,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.775,-4.188,2.413,,,,,,,0.896,,37.28,HBP,-1.70367,0.177985,0.00640304,0 gb1_K257T,gb1_257,gb1,gb1,P06654,0,NO,257,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.775,-3.31,1.535,,,,,,,0.896,,37.28,HBP,-1.70367,0.177985,0.00640304,0 gb1_K257Y,gb1_257,gb1,gb1,P06654,0,NO,257,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.775,-3.97,2.195,,,,,,,0.896,,37.28,HBP,-1.70367,0.177985,0.00640304,0 kka2_1:2_L193I,kka2_1:2_193,Kka2,kka2_1:2,P00552,1.55E-05,NO,193,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.983,-3.143,2.16,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.295029,0.00480179,1.55E-05 beta-lactamase_2500_D155W,beta-lactamase_2500_155,TEM-1,beta-lactamase_2500,P62593,7.16E-05,NO,155,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.889,-5.571,4.682,,0.049,,B,0.75,-0.9,2.386,,64.69,OAB,-1.62267,0.361275,0.00135315,7.16E-05 beta-lactamase_L150R,beta-lactamase_150,TEM-1,beta-lactamase,P62593,0.000199503,NO,150,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.326,-3.982,2.656,5.15566,,H,A,1.75,-0.2,1.615,,62.94,HHB,-1.86167,0.221079,0.00463171,0.000199503 beta-lactamase_39_V260W,beta-lactamase_39_260,TEM-1,beta-lactamase_39,P62593,0.000233556,NO,260,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.0495842,0.00471757,0.000233556 kka2_1:8_V36E,kka2_1:8_36,Kka2,kka2_1:8,P00552,0.000262747,NO,36,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-0.898,-3.776,2.878,,0.292,E,B,1.48,0.21,0.938,,52.27,HHH,-1.484,0.100394,0.00245633,0.000262747 kka2_1:8_V36E,kka2_1:8_36,Kka2,kka2_1:8,P00552,0.000262747,NO,36,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-0.898,-3.776,2.878,,0.292,E,B,1.48,0.21,0.938,,52.27,HHH,-1.484,0.100394,0.00245633,0.000262747 kka2_1:8_V36N,kka2_1:8_36,Kka2,kka2_1:8,P00552,0.000262747,NO,36,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-0.898,-4.196,3.298,,0.292,E,B,1.48,0.21,0.938,,52.27,HHH,-1.484,0.100394,0.00245633,0.000262747 kka2_1:8_V36N,kka2_1:8_36,Kka2,kka2_1:8,P00552,0.000262747,NO,36,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-0.898,-4.196,3.298,,0.292,E,B,1.48,0.21,0.938,,52.27,HHH,-1.484,0.100394,0.00245633,0.000262747 kka2_1:8_V36S,kka2_1:8_36,Kka2,kka2_1:8,P00552,0.000262747,NO,36,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-0.898,-3.684,2.786,,0.292,E,B,1.48,0.21,0.938,,52.27,HHH,-1.484,0.100394,0.00245633,0.000262747 kka2_1:8_V36S,kka2_1:8_36,Kka2,kka2_1:8,P00552,0.000262747,NO,36,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-0.898,-3.684,2.786,,0.292,E,B,1.48,0.21,0.938,,52.27,HHH,-1.484,0.100394,0.00245633,0.000262747 kka2_1:4_T187P,kka2_1:4_187,Kka2,kka2_1:4,P00552,0.000276687,NO,187,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.273,-3.887,2.614,,0.007,E,B,0.22,-0.85,2.73,,52.27,HPB,-1.06567,0.168804,0.00693073,0.000276687 beta-lactamase_I278K,beta-lactamase_278,TEM-1,beta-lactamase,P62593,0.000467814,NO,278,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.348,-3.761,2.413,5.35127,0.015,H,A,0.77,-0.85,2.718,,63.29,AHO,-1.41833,0.221079,0.0310297,0.000467814 beta-lactamase_N130K,beta-lactamase_130,TEM-1,beta-lactamase,P62593,0.000467814,NO,130,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-0.798,-3.232,2.434,5.26686,0.069,H,A,1.08,-0.74,,,,APP,-0.980667,0.221079,0.000683376,0.000467814 beta-lactamase_156_G43W,beta-lactamase_156_43,TEM-1,beta-lactamase_156,P62593,0.000565415,NO,43,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.62,-5.097,4.477,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.111618,0.00120151,0.000565415 PSD95pdz3_I359K,PSD95pdz3_359,PSD95pdz3,PSD95pdz3,P31016,0.000810115,NO,359,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.63,-3.589,1.959,5.35151,,,,,14.8012,,,,PHH,-1.58667,0.0758425,0.000580694,0.000810115 beta-lactamase_I243K,beta-lactamase_243,TEM-1,beta-lactamase,P62593,0.000854121,NO,243,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.532,-3.714,2.182,5.26886,,E,B,1.68,-1.24,2.289,,50,OHH,-1.46867,0.221079,0.00464034,0.000854121 beta-lactamase_S128A,beta-lactamase_128,TEM-1,beta-lactamase,P62593,0.000854121,NO,128,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-0.84,-2.628,1.788,5.37153,0.08,,L,0.73,-0.32,,,,HPA,-1.30233,0.221079,0.00071483,0.000854121 beta-lactamase_T69R,beta-lactamase_69,TEM-1,beta-lactamase,P62593,0.000854121,NO,69,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-0.973,-3.768,2.795,5.16042,,G,A,0.69,-1.24,0.505,,93.01,PPH,-1.01833,0.221079,0.00127498,0.000854121 beta-lactamase_156_V31Y,beta-lactamase_156_31,TEM-1,beta-lactamase_156,P62593,0.00126223,NO,31,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.822,-4.027,2.205,,,H,A,0.44,-0.46,4.126,,73.78,BHB,-2.03767,0.111618,0.00478065,0.00126223 beta-lactamase_P181K,beta-lactamase_181,TEM-1,beta-lactamase,P62593,0.00127716,NO,181,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.813,-3.483,2.67,5.14752,,H,A,1.1,-1.14,1.357,,61.54,HOH,-1.795,0.221079,0.000703122,0.00127716 beta-lactamase_V42R,beta-lactamase_42,TEM-1,beta-lactamase,P62593,0.00127716,NO,42,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.564,-4.138,2.574,5.27904,0.017,E,B,1.64,-0.51,2.024,,63.99,BHO,-1.042,0.221079,0.00404515,0.00127716 beta-lactamase_156_S68L,beta-lactamase_156_68,TEM-1,beta-lactamase_156,P62593,0.00132139,NO,68,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-0.913,-3.407,2.494,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.111618,0.000800065,0.00132139 beta-lactamase_156_D177H,beta-lactamase_156_177,TEM-1,beta-lactamase_156,P62593,0.00143736,NO,177,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.967,-4.511,3.544,,0.006,T,L,0.75,-1.02,2.072,,64.69,BAP,-0.873667,0.111618,0.000864022,0.00143736 beta-lactamase_K71N,beta-lactamase_71,TEM-1,beta-lactamase,P62593,0.0017426,NO,71,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-0.8,-3.448,2.648,5.15697,,H,A,1.3,-0.99,,,,HBH,-1.209,0.221079,0.00103192,0.0017426 kka2_1:2_V80W,kka2_1:2_80,Kka2,kka2_1:2,P00552,0.00201428,NO,80,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.144,-5.458,4.314,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.295029,0.00488211,0.00201428 kka2_1:2_G74F,kka2_1:2_74,Kka2,kka2_1:2,P00552,0.00212682,NO,74,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.18,-4.449,3.269,,0.621,T,l,0.75,0.2,1.446,,64.39,POH,-1.91667,0.295029,0.00587035,0.00212682 kka2_1:8_I207Y,kka2_1:8_207,Kka2,kka2_1:8,P00552,0.00232755,NO,207,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.175,-4.053,2.878,,0.293,,B,1.52,-1.12,1.306,,56.06,HHA,-1.07733,0.100394,0.00611824,0.00232755 kka2_1:8_I207Y,kka2_1:8_207,Kka2,kka2_1:8,P00552,0.00232755,NO,207,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.175,-4.053,2.878,,0.293,,B,1.52,-1.12,1.306,,56.06,HHA,-1.07733,0.100394,0.00611824,0.00232755 beta-lactamase_Y44N,beta-lactamase_44,TEM-1,beta-lactamase,P62593,0.00244065,NO,44,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-2.547,-4.162,1.615,5.6273,,E,B,2.55,-0.45,2.683,,73.78,OHH,-1.86267,0.221079,0.00426364,0.00244065 kka2_1:1_A78M,kka2_1:1_78,Kka2,kka2_1:1,P00552,0.00259893,NO,78,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.744,-4.709,2.965,,0.078,.,B,0.46,-0.53,0.206,,56.06,OHH,-1.863,0.520039,0.00457299,0.00259893 beta-lactamase_I278E,beta-lactamase_278,TEM-1,beta-lactamase,P62593,0.00282851,NO,278,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.348,-3.846,2.498,5.35127,0.015,H,A,0.77,-0.85,2.718,,63.29,AHO,-1.41833,0.221079,0.0310297,0.00282851 beta-lactamase_V42P,beta-lactamase_42,TEM-1,beta-lactamase,P62593,0.00282851,NO,42,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.564,-4.095,2.531,5.27904,0.017,E,B,1.64,-0.51,2.024,,63.99,BHO,-1.042,0.221079,0.00404515,0.00282851 kka2_1:4_G205K,kka2_1:4_205,Kka2,kka2_1:4,P00552,0.00291117,NO,205,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.596,-3.71,3.114,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.168804,0.00221855,0.00291117 beta-lactamase_2500_S68A,beta-lactamase_2500_68,TEM-1,beta-lactamase_2500,P62593,0.00292097,NO,68,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-0.913,-2.711,1.798,,0.064,G,A,0.27,-1.03,2.824,,64.69,HPP,-1.37233,0.361275,0.000800065,0.00292097 beta-lactamase_625_E164Q,beta-lactamase_625_164,TEM-1,beta-lactamase_625,P62593,0.00301892,NO,164,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-0.948,-3.358,2.41,,0.011,T,B,1.04,-0.4,1.321,,64.69,HAO,-1.388,0.213352,0.00137286,0.00301892 beta-lactamase_L188R,beta-lactamase_188,TEM-1,beta-lactamase,P62593,0.00310346,NO,188,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.166,-3.976,2.81,5.55434,,H,A,1.07,-0.3,1.574,,60.14,PHB,-1.47033,0.221079,0.00295687,0.00310346 beta-lactamase_V257R,beta-lactamase_257,TEM-1,beta-lactamase,P62593,0.00313887,NO,257,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.533,-4.11,2.577,5.31999,,E,B,0.96,-0.7,1.463,,58.74,HHH,-1.70967,0.221079,0.00756629,0.00313887 Pab1_K131P,Pab1_131,Pab1,Pab1,P04147,0.00316641,NO,131,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.083,-3.472,2.389,,0.462,E,B,1.82,0.57,,,,HBP,-1.12467,0.175299,0.000349395,0.00316641 beta-lactamase_156_T69K,beta-lactamase_156_69,TEM-1,beta-lactamase_156,P62593,0.0032585,NO,69,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-0.973,-3.493,2.52,,,G,A,0.22,-1.24,4.194,,93.01,PPH,-1.01833,0.111618,0.00127498,0.0032585 kka2_1:2_L57E,kka2_1:2_57,Kka2,kka2_1:2,P00552,0.00363313,NO,57,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.898,-3.855,1.957,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.295029,0.00723769,0.00363313 kka2_1:4_R253W,kka2_1:4_253,Kka2,kka2_1:4,P00552,0.00368148,NO,253,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.356,-5.444,4.088,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.168804,0.0144195,0.00368148 kka2_1:1_Y218N,kka2_1:1_218,Kka2,kka2_1:1,P00552,0.00369812,NO,218,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-1.438,-3.871,2.433,,0.122,H,A,1.25,-0.69,3.059,,56.06,BHP,-1.17533,0.520039,0.0126098,0.00369812 beta-lactamase_625_A133W,beta-lactamase_625_133,TEM-1,beta-lactamase_625,P62593,0.00393612,NO,133,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.186,-5.303,4.117,,,H,A,0.46,-0.86,0.373,,67.83,HHP,-0.988333,0.213352,0.00468022,0.00393612 beta-lactamase_2500_I245Y,beta-lactamase_2500_245,TEM-1,beta-lactamase_2500,P62593,0.00395285,NO,245,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.361275,0.00391032,0.00395285 beta-lactamase_C121D,beta-lactamase_121,TEM-1,beta-lactamase,P62593,0.00418598,NO,121,C,D,CD,Special,negativeCharge,5.07,5.0516,-0.0184,154,121,133,12,108.5,111.1,2.6,-0.953,-3.916,2.963,5.12205,,H,A,2.8,-0.81,7.644,,63.29,HOP,-1.46767,0.221079,0.000744322,0.00418598 beta-lactamase_C75K,beta-lactamase_75,TEM-1,beta-lactamase,P62593,0.00418598,NO,75,C,K,CK,Special,PositiveCharge,5.07,9.74,4.67,202,121,146,25,108.5,168.6,60.1,-1.245,-3.786,2.541,4.88171,,H,A,0.25,-0.87,0.876,,50,HOO,-1.24333,0.221079,0.0034616,0.00418598 beta-lactamase_I259D,beta-lactamase_259,TEM-1,beta-lactamase,P62593,0.00418598,NO,259,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.522,-4.007,2.485,5.28457,,E,B,1,-0.8,1.24,,64.34,HHH,-1.53267,0.221079,0.0070773,0.00418598 beta-lactamase_L79P,beta-lactamase_79,TEM-1,beta-lactamase,P62593,0.00418598,NO,79,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.842,-4.102,3.26,4.98681,0.007,H,A,1.07,-0.16,0.823,,50.35,HHP,-1.44333,0.221079,0.000947397,0.00418598 beta-lactamase_S128I,beta-lactamase_128,TEM-1,beta-lactamase,P62593,0.00418598,NO,128,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-0.84,-3.785,2.945,5.37153,0.08,,L,0.73,-0.32,,,,HPA,-1.30233,0.221079,0.00071483,0.00418598 beta-lactamase_T158E,beta-lactamase_158,TEM-1,beta-lactamase,P62593,0.00418598,NO,158,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.116,-3.449,2.333,5.32011,0.036,,B,0.98,-0.85,2.755,,69.58,HPB,-1.269,0.221079,0.00341825,0.00418598 beta-lactamase_156_I277K,beta-lactamase_156_277,TEM-1,beta-lactamase_156,P62593,0.00434884,NO,277,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.111618,0.0169305,0.00434884 beta-lactamase_S68G,beta-lactamase_68,TEM-1,beta-lactamase,P62593,0.00447009,NO,68,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-0.913,-2.934,2.021,4.94745,0.064,G,A,0.77,-1.03,3.202,,64.69,HPP,-1.37233,0.221079,0.000800065,0.00447009 beta-lactamase_2500_G76N,beta-lactamase_2500_76,TEM-1,beta-lactamase_2500,P62593,0.00448956,NO,76,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.189,-3.655,2.466,,,H,A,0.29,-0.67,1.012,,67.83,OOH,-1.22267,0.361275,0.00476637,0.00448956 Pab1_G150H,Pab1_150,Pab1,Pab1,P04147,0.0046937,NO,150,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.809,-4.497,3.688,,0.287,S,b,0.23,0.53,,,,HOA,-1.45233,0.175299,0.000323835,0.0046937 beta-lactamase_C121Y,beta-lactamase_121,TEM-1,beta-lactamase,P62593,0.00471709,NO,121,C,Y,CY,Special,Hydrophobic,5.07,5.66,0.59,194,121,181,60,108.5,193.6,85.1,-0.953,-4.188,3.235,5.12205,,H,A,2.8,-0.81,7.644,,63.29,HOP,-1.46767,0.221079,0.000744322,0.00471709 beta-lactamase_I244K,beta-lactamase_244,TEM-1,beta-lactamase,P62593,0.00474977,NO,244,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.555,-3.812,2.257,5.35885,,E,B,0.01,-0.84,0.379,,77.62,HHH,-1.385,0.221079,0.00605379,0.00474977 beta-lactamase_A124K,beta-lactamase_124,TEM-1,beta-lactamase,P62593,0.00500029,NO,124,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.181,-3.561,2.38,4.58507,,H,A,0.58,-0.9,2.273,,64.34,HHH,-1.152,0.221079,0.00481399,0.00500029 kka2_1:4_A78W,kka2_1:4_78,Kka2,kka2_1:4,P00552,0.00508554,NO,78,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.744,-5.551,3.807,,0.078,.,B,0.46,-0.53,0.594,,56.06,OHH,-1.863,0.168804,0.00457299,0.00508554 beta-lactamase_625_G234H,beta-lactamase_625_234,TEM-1,beta-lactamase_625,P62593,0.00508852,NO,234,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.62,-4.68,4.06,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.213352,0.000889577,0.00508852 beta-lactamase_A230P,beta-lactamase_230,TEM-1,beta-lactamase,P62593,0.0052965,NO,230,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.154,-3.805,2.651,4.54336,0.01,E,B,0.75,-1.17,1.97,,50,HHA,-1.079,0.221079,0.00516841,0.0052965 beta-lactamase_K232Y,beta-lactamase_232,TEM-1,beta-lactamase,P62593,0.0052965,NO,232,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.012,-4.205,3.193,5.18286,,E,B,2.92,-1.1,1.174,,65.03,ABP,-1.238,0.221079,0.00313441,0.0052965 beta-lactamase_0_A123I,beta-lactamase_0_123,TEM-1,beta-lactamase_0,P62593,0.00542675,NO,123,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.834,-3.433,2.599,,0.039,H,A,0.46,-0.72,1.308,,41.26,PHH,-1.47367,0.0500837,0.0010157,0.00542675 kka2_1:4_V214P,kka2_1:4_214,Kka2,kka2_1:4,P00552,0.00549173,NO,214,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.261,-4.14,2.879,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.168804,0.00692782,0.00549173 beta-lactamase_I256R,beta-lactamase_256,TEM-1,beta-lactamase,P62593,0.00560641,NO,256,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.621,-4.2,2.579,5.3196,,E,B,1,-0.84,1.615,,73.08,BHH,-1.80667,0.221079,0.00710634,0.00560641 kka2_1:8_D208I,kka2_1:8_208,Kka2,kka2_1:8,P00552,0.00574028,NO,208,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.708,-4.039,3.331,,0.36,,l,0.29,-1.01,,,,HAO,-0.929667,0.100394,0.00212588,0.00574028 kka2_1:8_D208I,kka2_1:8_208,Kka2,kka2_1:8,P00552,0.00574028,NO,208,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.708,-4.039,3.331,,0.36,,l,0.29,-1.01,,,,HAO,-0.929667,0.100394,0.00212588,0.00574028 kka2_1:2_V198P,kka2_1:2_198,Kka2,kka2_1:2,P00552,0.00576025,NO,198,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.719,-3.911,2.192,,0.05,E,B,1.48,-0.95,1.074,,56.06,HHA,-1.88667,0.295029,0.00835002,0.00576025 beta-lactamase_625_G243W,beta-lactamase_625_243,TEM-1,beta-lactamase_625,P62593,0.00586306,NO,243,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.213352,0.00464034,0.00586306 beta-lactamase_39_S68D,beta-lactamase_39_68,TEM-1,beta-lactamase_39,P62593,0.00589672,NO,68,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-0.913,-3.241,2.328,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.0495842,0.000800065,0.00589672 beta-lactamase_G76K,beta-lactamase_76,TEM-1,beta-lactamase,P62593,0.00593116,NO,76,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.189,-3.631,2.442,4.73862,,H,A,2.05,-0.67,3.059,,67.83,OOH,-1.22267,0.221079,0.00476637,0.00593116 beta-lactamase_K232H,beta-lactamase_232,TEM-1,beta-lactamase,P62593,0.00593116,NO,232,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.012,-4.433,3.421,5.18286,,E,B,2.92,-1.1,1.174,,65.03,ABP,-1.238,0.221079,0.00313441,0.00593116 beta-lactamase_K232Q,beta-lactamase_232,TEM-1,beta-lactamase,P62593,0.00593116,NO,232,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.012,-3.492,2.48,5.18286,,E,B,2.92,-1.1,1.174,,65.03,ABP,-1.238,0.221079,0.00313441,0.00593116 beta-lactamase_K71S,beta-lactamase_71,TEM-1,beta-lactamase,P62593,0.00593116,NO,71,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-0.8,-3.161,2.361,5.15697,,H,A,1.3,-0.99,,,,HBH,-1.209,0.221079,0.00103192,0.00593116 beta-lactamase_T179D,beta-lactamase_179,TEM-1,beta-lactamase,P62593,0.00593116,NO,179,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.085,-3.517,2.432,5.07116,,E,B,0.8,-1.38,1.859,,73.08,PPH,-1.557,0.221079,0.00226045,0.00593116 PSD95pdz3_H372M,PSD95pdz3_372,PSD95pdz3,PSD95pdz3,P31016,0.00610702,NO,372,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-1.627,-4.387,2.76,5.5607,,,,,17.008,,,,PBA,-1.63033,0.0758425,0.00040301,0.00610702 beta-lactamase_2500_S68E,beta-lactamase_2500_68,TEM-1,beta-lactamase_2500,P62593,0.00613737,NO,68,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-0.913,-3.241,2.328,,0.064,G,A,0.27,-1.03,2.824,,64.69,HPP,-1.37233,0.361275,0.000800065,0.00613737 beta-lactamase_625_A132K,beta-lactamase_625_132,TEM-1,beta-lactamase_625,P62593,0.00624126,NO,132,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.9,-3.501,2.601,,,H,A,0.46,-0.93,0.316,,64.69,PHH,-1.138,0.213352,0.000962524,0.00624126 kka2_1:2_M120S,kka2_1:2_120,Kka2,kka2_1:2,P00552,0.0062584,NO,120,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-3.877,-3.662,-0.215,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.295029,0.00265808,0.0062584 beta-lactamase_2500_E164L,beta-lactamase_2500_164,TEM-1,beta-lactamase_2500,P62593,0.00631543,NO,164,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-0.948,-3.627,2.679,,0.011,T,B,1.04,-0.4,0.352,,64.69,HAO,-1.388,0.361275,0.00137286,0.00631543 beta-lactamase_S68H,beta-lactamase_68,TEM-1,beta-lactamase,P62593,0.00634186,NO,68,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-0.913,-4.418,3.505,4.94745,0.064,G,A,0.77,-1.03,3.202,,64.69,HPP,-1.37233,0.221079,0.000800065,0.00634186 beta-lactamase_2500_A133L,beta-lactamase_2500_133,TEM-1,beta-lactamase_2500,P62593,0.00651901,NO,133,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.186,-3.396,2.21,,,H,A,0.46,-0.86,2.649,,67.83,HHP,-0.988333,0.361275,0.00468022,0.00651901 beta-lactamase_2500_M66W,beta-lactamase_2500_66,TEM-1,beta-lactamase_2500,P62593,0.00689731,NO,66,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.362,-5.087,3.725,,0.013,,A,0.55,-0.7,0.502,,73.08,OHH,-1.49567,0.361275,0.00412876,0.00689731 beta-lactamase_2500_R257P,beta-lactamase_2500_257,TEM-1,beta-lactamase_2500,P62593,0.00698207,NO,257,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.361275,0.00756629,0.00698207 beta-lactamase_0_V117P,beta-lactamase_0_117,TEM-1,beta-lactamase_0,P62593,0.00698675,NO,117,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.53,-4.14,2.61,,,H,A,0.44,-0.34,1.16,,65.03,PHB,-1.741,0.0500837,0.00467906,0.00698675 beta-lactamase_G236P,beta-lactamase_236,TEM-1,beta-lactamase,P62593,0.00700506,NO,236,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.784,-3.879,3.095,4.7915,0.241,,b,0.23,-0.59,1.883,,64.69,HOA,-1.36933,0.221079,0.00162372,0.00700506 beta-lactamase_V42D,beta-lactamase_42,TEM-1,beta-lactamase,P62593,0.00700506,NO,42,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.564,-4.059,2.495,5.27904,0.017,E,B,1.64,-0.51,2.024,,63.99,BHO,-1.042,0.221079,0.00404515,0.00700506 beta-lactamase_2500_G76Q,beta-lactamase_2500_76,TEM-1,beta-lactamase_2500,P62593,0.00714858,NO,76,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.189,-4.074,2.885,,,H,A,0.29,-0.67,1.012,,67.83,OOH,-1.22267,0.361275,0.00476637,0.00714858 kka2_1:4_M116W,kka2_1:4_116,Kka2,kka2_1:4,P00552,0.0071722,NO,116,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-2.482,-5.227,2.745,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.168804,0.00745147,0.0071722 beta-lactamase_A132E,beta-lactamase_132,TEM-1,beta-lactamase,P62593,0.00740079,NO,132,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.9,-3.484,2.584,4.58504,,H,A,2.34,-0.93,2.217,,64.69,PHH,-1.138,0.221079,0.000962524,0.00740079 beta-lactamase_G43W,beta-lactamase_43,TEM-1,beta-lactamase,P62593,0.00740079,NO,43,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.62,-5.097,4.477,5.28886,,E,B,0.77,-0.78,,,,HOH,-1.577,0.221079,0.00120151,0.00740079 beta-lactamase_2500_G76K,beta-lactamase_2500_76,TEM-1,beta-lactamase_2500,P62593,0.00751096,NO,76,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.189,-3.631,2.442,,,H,A,0.29,-0.67,1.012,,67.83,OOH,-1.22267,0.361275,0.00476637,0.00751096 beta-lactamase_D129K,beta-lactamase_129,TEM-1,beta-lactamase,P62593,0.00760659,NO,129,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.816,-3.42,2.604,4.84204,,,B,1.33,-0.69,0.548,,34.97,PAP,-0.818,0.221079,0.00109178,0.00760659 beta-lactamase_156_E164M,beta-lactamase_156_164,TEM-1,beta-lactamase_156,P62593,0.00794609,NO,164,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-0.948,-4.749,3.801,,0.011,T,B,1.04,-0.4,3.445,,64.69,HAO,-1.388,0.111618,0.00137286,0.00794609 Ubiquitin_R42P,Ubiquitin_42,Uba1,Ubiquitin,P0CG48,0.00806452,NO,42,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.571,-3.959,2.388,5.07805,0.244,E,B,0.68,-0.54,1.976,,72.85,PBH,-1.38967,0.205827,0.000622265,0.00806452 kka2_1:1_V186F,kka2_1:1_186,Kka2,kka2_1:1,P00552,0.00810483,NO,186,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.011,-2.866,1.855,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.520039,0.00409703,0.00810483 beta-lactamase_2500_D161L,beta-lactamase_2500_161,TEM-1,beta-lactamase_2500,P62593,0.00819506,NO,161,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.891,-3.777,2.886,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.361275,0.000897697,0.00819506 beta-lactamase_E164T,beta-lactamase_164,TEM-1,beta-lactamase,P62593,0.00825815,NO,164,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-0.948,-3.491,2.543,5.3334,0.011,T,B,1.62,-0.4,1.055,,64.69,HAO,-1.388,0.221079,0.00137286,0.00825815 beta-lactamase_E164V,beta-lactamase_164,TEM-1,beta-lactamase,P62593,0.00825815,NO,164,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-0.948,-3.599,2.651,5.3334,0.011,T,B,1.62,-0.4,1.055,,64.69,HAO,-1.388,0.221079,0.00137286,0.00825815 beta-lactamase_K71T,beta-lactamase_71,TEM-1,beta-lactamase,P62593,0.00825815,NO,71,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-0.8,-3.421,2.621,5.15697,,H,A,1.3,-0.99,,,,HBH,-1.209,0.221079,0.00103192,0.00825815 beta-lactamase_V72D,beta-lactamase_72,TEM-1,beta-lactamase,P62593,0.00825815,NO,72,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.658,-3.942,2.284,5.80324,,H,A,2.78,-1.03,2.964,,65.73,BHH,-1.32167,0.221079,0.00501194,0.00825815 beta-lactamase_625_D129W,beta-lactamase_625_129,TEM-1,beta-lactamase_625,P62593,0.00831865,NO,129,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.816,-5.545,4.729,,,,B,0.75,-0.69,0.171,,34.97,PAP,-0.818,0.213352,0.00109178,0.00831865 kka2_1:8_A78I,kka2_1:8_78,Kka2,kka2_1:8,P00552,0.00844516,NO,78,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.744,-3.934,2.19,,0.078,,B,1.04,-0.53,1.251,,56.06,OHH,-1.863,0.100394,0.00457299,0.00844516 kka2_1:8_A78I,kka2_1:8_78,Kka2,kka2_1:8,P00552,0.00844516,NO,78,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.744,-3.934,2.19,,0.078,,B,1.04,-0.53,1.251,,56.06,OHH,-1.863,0.100394,0.00457299,0.00844516 beta-lactamase_Y260D,beta-lactamase_260,TEM-1,beta-lactamase,P62593,0.00872358,NO,260,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-1.101,-4.003,2.902,5.50878,,E,B,0.73,-1.04,0.865,,60.49,HHP,-1.83433,0.221079,0.00471757,0.00872358 beta-lactamase_2500_I125Q,beta-lactamase_2500_125,TEM-1,beta-lactamase_2500,P62593,0.00875843,NO,125,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.441,-4.226,2.785,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.361275,0.00383964,0.00875843 kka2_1:8_A144Y,kka2_1:8_144,Kka2,kka2_1:8,P00552,0.00878171,NO,144,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.859,-4.19,3.331,,,H,A,1.04,0.21,1.118,,52.65,BHB,-1.72933,0.100394,0.00231095,0.00878171 kka2_1:8_A144Y,kka2_1:8_144,Kka2,kka2_1:8,P00552,0.00878171,NO,144,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.859,-4.19,3.331,,,H,A,1.04,0.21,1.118,,52.65,BHB,-1.72933,0.100394,0.00231095,0.00878171 beta-lactamase_I275K,beta-lactamase_275,TEM-1,beta-lactamase,P62593,0.00881977,NO,275,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.397,-3.875,2.478,5.3999,0.015,H,A,1,-0.52,0.836,,62.59,PHH,-1.541,0.221079,0.0141984,0.00881977 beta-lactamase_625_G43L,beta-lactamase_625_43,TEM-1,beta-lactamase_625,P62593,0.00884056,NO,43,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.62,-3.808,3.188,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.213352,0.00120151,0.00884056 beta-lactamase_39_S68Q,beta-lactamase_39_68,TEM-1,beta-lactamase_39,P62593,0.00911138,NO,68,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-0.913,-3.7,2.787,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.0495842,0.000800065,0.00911138 kka2_1:4_Y22P,kka2_1:4_22,Kka2,kka2_1:4,P00552,0.00929548,NO,22,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-1.583,-4.113,2.53,,0.122,.,B,0.21,-0.8,1.838,,65.53,OHA,-1.80333,0.168804,0.00598977,0.00929548 beta-lactamase_I275D,beta-lactamase_275,TEM-1,beta-lactamase,P62593,0.00942156,NO,275,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.397,-4.036,2.639,5.3999,0.015,H,A,1,-0.52,0.836,,62.59,PHH,-1.541,0.221079,0.0141984,0.00942156 beta-lactamase_N130R,beta-lactamase_130,TEM-1,beta-lactamase,P62593,0.00942156,NO,130,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-0.798,-3.483,2.685,5.26686,0.069,H,A,1.08,-0.74,,,,APP,-0.980667,0.221079,0.000683376,0.00942156 kka2_1:4_F37D,kka2_1:4_37,Kka2,kka2_1:4,P00552,0.00951004,NO,37,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.427,-4.022,2.595,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.168804,0.00586193,0.00951004 beta-lactamase_2500_S68W,beta-lactamase_2500_68,TEM-1,beta-lactamase_2500,P62593,0.00951119,NO,68,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-0.913,-5.371,4.458,,0.064,G,A,0.27,-1.03,2.824,,64.69,HPP,-1.37233,0.361275,0.000800065,0.00951119 kka2_1:4_V153D,kka2_1:4_153,Kka2,kka2_1:4,P00552,0.00959745,NO,153,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.092,-4.005,2.913,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.168804,0.00501119,0.00959745 kka2_1:4_V186F,kka2_1:4_186,Kka2,kka2_1:4,P00552,0.00966624,NO,186,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.011,-2.866,1.855,,,E,B,0.44,-0.61,0.679,,45.83,HHP,-1.10967,0.168804,0.00409703,0.00966624 kka2_1:8_V185N,kka2_1:8_185,Kka2,kka2_1:8,P00552,0.00978928,NO,185,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.045,-4.197,3.152,,0.058,E,B,1.48,-0.49,1.234,,46.97,HHH,-1.184,0.100394,0.00367031,0.00978928 kka2_1:8_V185N,kka2_1:8_185,Kka2,kka2_1:8,P00552,0.00978928,NO,185,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.045,-4.197,3.152,,0.058,E,B,1.48,-0.49,1.234,,46.97,HHH,-1.184,0.100394,0.00367031,0.00978928 beta-lactamase_156_K71I,beta-lactamase_156_71,TEM-1,beta-lactamase_156,P62593,0.00981505,NO,71,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-0.8,-4.01,3.21,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.111618,0.00103192,0.00981505 beta-lactamase_Y44R,beta-lactamase_44,TEM-1,beta-lactamase,P62593,0.00997275,NO,44,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-2.547,-4.123,1.576,5.6273,,E,B,2.55,-0.45,2.683,,73.78,OHH,-1.86267,0.221079,0.00426364,0.00997275 beta-lactamase_A235P,beta-lactamase_235,TEM-1,beta-lactamase,P62593,0.0100679,NO,235,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.266,-3.821,2.555,4.83024,0.32,E,B,0.52,-0.86,1.344,,50,OHO,-0.89,0.221079,0.00493474,0.0100679 beta-lactamase_0_C121Q,beta-lactamase_0_121,TEM-1,beta-lactamase_0,P62593,0.0102744,NO,121,C,Q,CQ,Special,Polar,5.07,6.24429,1.17429,154,121,146,25,108.5,143.8,35.3,-0.953,-4.222,3.269,,,H,A,0.46,-0.81,3.302,,63.29,HOP,-1.46767,0.0500837,0.000744322,0.0102744 beta-lactamase_S68N,beta-lactamase_68,TEM-1,beta-lactamase,P62593,0.0102942,NO,68,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-0.913,-2.44,1.527,4.94745,0.064,G,A,0.77,-1.03,3.202,,64.69,HPP,-1.37233,0.221079,0.000800065,0.0102942 beta-lactamase_0_A123W,beta-lactamase_0_123,TEM-1,beta-lactamase_0,P62593,0.0104856,NO,123,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.834,-5.348,4.514,,0.039,H,A,0.46,-0.72,1.308,,41.26,PHH,-1.47367,0.0500837,0.0010157,0.0104856 beta-lactamase_625_Y44K,beta-lactamase_625_44,TEM-1,beta-lactamase_625,P62593,0.0106138,NO,44,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-2.547,-3.823,1.276,,,E,B,0.21,-0.45,2.371,,73.78,OHH,-1.86267,0.213352,0.00426364,0.0106138 kka2_1:4_G210W,kka2_1:4_210,Kka2,kka2_1:4,P00552,0.0106234,NO,210,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.095,-5.322,4.227,,0.103,T,A,0.29,-0.62,0.271,,50,OOB,-0.966667,0.168804,0.00598378,0.0106234 beta-lactamase_156_K71D,beta-lactamase_156_71,TEM-1,beta-lactamase_156,P62593,0.0110691,NO,71,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-0.8,-3.469,2.669,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.111618,0.00103192,0.0110691 beta-lactamase_G242R,beta-lactamase_242,TEM-1,beta-lactamase,P62593,0.0112586,NO,242,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.319,-3.802,2.483,4.68003,,E,B,0.87,-1.05,1.079,,50,BOH,-1.428,0.221079,0.00452879,0.0112586 beta-lactamase_E164M,beta-lactamase_164,TEM-1,beta-lactamase,P62593,0.0115158,NO,164,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-0.948,-4.749,3.801,5.3334,0.011,T,B,1.62,-0.4,1.055,,64.69,HAO,-1.388,0.221079,0.00137286,0.0115158 beta-lactamase_L247D,beta-lactamase_247,TEM-1,beta-lactamase,P62593,0.0115158,NO,247,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.48,-4.066,2.586,5.28771,0.007,E,B,2.89,-0.72,2.951,,63.99,HHO,-1.79833,0.221079,0.00611275,0.0115158 beta-lactamase_N134P,beta-lactamase_134,TEM-1,beta-lactamase,P62593,0.0115158,NO,134,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-0.879,-3.877,2.998,5.07245,0.138,H,A,0.09,-0.6,1.441,,53.15,HPH,-1.02233,0.221079,0.000644786,0.0115158 beta-lactamase_S128N,beta-lactamase_128,TEM-1,beta-lactamase,P62593,0.0115158,NO,128,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-0.84,-3.223,2.383,5.37153,0.08,,L,0.73,-0.32,,,,HPA,-1.30233,0.221079,0.00071483,0.0115158 beta-lactamase_2500_P65W,beta-lactamase_2500_65,TEM-1,beta-lactamase_2500,P62593,0.0117131,NO,65,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.894,-5.47,4.576,,0.098,E,B,0.52,-0.62,0.3,,40.56,HOH,-1.03233,0.361275,0.00152776,0.0117131 kka2_1:4_L60K,kka2_1:4_60,Kka2,kka2_1:4,P00552,0.0117265,NO,60,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.997,-3.814,2.817,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.168804,0.00262176,0.0117265 kka2_1:8_K112S,kka2_1:8_112,Kka2,kka2_1:8,P00552,0.0117952,NO,112,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-2.491,-2.816,0.325,,0.076,H,A,1.3,-1.37,10.58,10.58,56.06,ABH,-2.00133,0.100394,0.00645389,0.0117952 kka2_1:8_K112S,kka2_1:8_112,Kka2,kka2_1:8,P00552,0.0117952,NO,112,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-2.491,-2.816,0.325,,0.076,H,A,1.3,-1.37,10.58,10.58,56.06,ABH,-2.00133,0.100394,0.00645389,0.0117952 beta-lactamase_39_I261P,beta-lactamase_39_261,TEM-1,beta-lactamase_39,P62593,0.0122985,NO,261,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.0495842,0.0123091,0.0122985 beta-lactamase_156_S233I,beta-lactamase_156_233,TEM-1,beta-lactamase_156,P62593,0.0123929,NO,233,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.886,-3.784,1.898,,0.016,E,B,0.27,-1.01,4.111,,77.62,BPO,-1.17267,0.111618,0.00311415,0.0123929 beta-lactamase_2500_A230P,beta-lactamase_2500_230,TEM-1,beta-lactamase_2500,P62593,0.0124194,NO,230,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.154,-3.805,2.651,,0.01,E,B,0.46,-1.17,1.171,,50,HHA,-1.079,0.361275,0.00516841,0.0124194 kka2_1:2_A34Y,kka2_1:2_34,Kka2,kka2_1:2,P00552,0.0124856,NO,34,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.928,-4.223,3.295,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.295029,0.00343484,0.0124856 PSD95pdz3_V328D,PSD95pdz3_328,PSD95pdz3,PSD95pdz3,P31016,0.0127126,NO,328,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.465,-3.6,2.135,5.28275,,,,,16.8775,,,,HHO,-1.36767,0.0758425,0.000986706,0.0127126 kka2_1:8_E59Y,kka2_1:8_59,Kka2,kka2_1:8,P00552,0.0127936,NO,59,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-0.952,-4.251,3.299,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.100394,0.00280355,0.0127936 kka2_1:8_E59Y,kka2_1:8_59,Kka2,kka2_1:8,P00552,0.0127936,NO,59,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-0.952,-4.251,3.299,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.100394,0.00280355,0.0127936 beta-lactamase_2500_T69F,beta-lactamase_2500_69,TEM-1,beta-lactamase_2500,P62593,0.0128864,NO,69,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-0.973,-4.127,3.154,,,G,A,0.22,-1.24,2.05,,93.01,PPH,-1.01833,0.361275,0.00127498,0.0128864 beta-lactamase_I256K,beta-lactamase_256,TEM-1,beta-lactamase,P62593,0.012912,NO,256,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.621,-3.903,2.282,5.3196,,E,B,1,-0.84,1.615,,73.08,BHH,-1.80667,0.221079,0.00710634,0.012912 kka2_1:1_G189E,kka2_1:1_189,Kka2,kka2_1:1,P00552,0.01297,NO,189,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.596,-3.693,3.097,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.520039,0.00253688,0.01297 kka2_1:8_G213I,kka2_1:8_213,Kka2,kka2_1:8,P00552,0.0131257,NO,213,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.596,-4.264,3.668,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.100394,0.00187654,0.0131257 kka2_1:8_G213I,kka2_1:8_213,Kka2,kka2_1:8,P00552,0.0131257,NO,213,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.596,-4.264,3.668,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.100394,0.00187654,0.0131257 beta-lactamase_2500_I245N,beta-lactamase_2500_245,TEM-1,beta-lactamase_2500,P62593,0.0135127,NO,245,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.361275,0.00391032,0.0135127 kka2_1:4_V113P,kka2_1:4_113,Kka2,kka2_1:4,P00552,0.0136059,NO,113,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.233,-4.102,2.869,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.168804,0.00650191,0.0136059 beta-lactamase_I259E,beta-lactamase_259,TEM-1,beta-lactamase,P62593,0.0136876,NO,259,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.522,-3.856,2.334,5.28457,,E,B,1,-0.8,1.24,,64.34,HHH,-1.53267,0.221079,0.0070773,0.0136876 kka2_1:8_L260N,kka2_1:8_260,Kka2,kka2_1:8,P00552,0.013789,NO,260,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.741,-4.151,3.41,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.100394,0.0233782,0.013789 kka2_1:8_L260N,kka2_1:8_260,Kka2,kka2_1:8,P00552,0.013789,NO,260,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.741,-4.151,3.41,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.100394,0.0233782,0.013789 beta-lactamase_0_A123Y,beta-lactamase_0_123,TEM-1,beta-lactamase_0,P62593,0.0138592,NO,123,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.834,-4.16,3.326,,0.039,H,A,0.46,-0.72,1.308,,41.26,PHH,-1.47367,0.0500837,0.0010157,0.0138592 beta-lactamase_F64G,beta-lactamase_64,TEM-1,beta-lactamase,P62593,0.0141813,NO,64,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-0.841,-3.583,2.742,5.70769,0.006,E,B,1.33,-0.95,,,,BHO,-0.892667,0.221079,0.000947691,0.0141813 beta-lactamase_2500_M66D,beta-lactamase_2500_66,TEM-1,beta-lactamase_2500,P62593,0.0142323,NO,66,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.362,-4.069,2.707,,0.013,,A,0.55,-0.7,0.502,,73.08,OHH,-1.49567,0.361275,0.00412876,0.0142323 beta-lactamase_2500_V42P,beta-lactamase_2500_42,TEM-1,beta-lactamase_2500,P62593,0.0143308,NO,42,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.564,-4.095,2.531,,0.017,E,B,0.44,-0.51,1.86,,63.99,BHO,-1.042,0.361275,0.00404515,0.0143308 beta-lactamase_A185P,beta-lactamase_185,TEM-1,beta-lactamase,P62593,0.014523,NO,185,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.406,-2.861,1.455,4.89877,,H,A,2.34,-1.02,2.999,,65.03,HHP,-1.84033,0.221079,0.00467449,0.014523 beta-lactamase_2500_G234T,beta-lactamase_2500_234,TEM-1,beta-lactamase_2500,P62593,0.0146281,NO,234,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.62,-3.646,3.026,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.361275,0.000889577,0.0146281 kka2_1:2_A78N,kka2_1:2_78,Kka2,kka2_1:2,P00552,0.0146688,NO,78,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.744,-3.971,2.227,,0.078,.,B,0.46,-0.53,0.206,,56.06,OHH,-1.863,0.295029,0.00457299,0.0146688 beta-lactamase_0_A123C,beta-lactamase_0_123,TEM-1,beta-lactamase_0,P62593,0.0146754,NO,123,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.834,-4.461,3.627,,0.039,H,A,0.46,-0.72,1.308,,41.26,PHH,-1.47367,0.0500837,0.0010157,0.0146754 kka2_1:4_I221R,kka2_1:4_221,Kka2,kka2_1:4,P00552,0.0147781,NO,221,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.739,-4.17,2.431,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.168804,0.00945908,0.0147781 beta-lactamase_39_S128K,beta-lactamase_39_128,TEM-1,beta-lactamase_39,P62593,0.0149416,NO,128,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-0.84,-3.232,2.392,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.0495842,0.00071483,0.0149416 beta-lactamase_625_V78R,beta-lactamase_625_78,TEM-1,beta-lactamase_625,P62593,0.0150922,NO,78,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.459,-4.181,2.722,,,H,A,0.44,-0.47,2.045,,63.64,HHH,-1.17833,0.213352,0.00492501,0.0150922 beta-lactamase_39_G236P,beta-lactamase_39_236,TEM-1,beta-lactamase_39,P62593,0.0152177,NO,236,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.784,-3.879,3.095,,0.241,,b,0.29,-0.59,1.883,,64.69,HOO,-1.025,0.0495842,0.00162372,0.0152177 PSD95pdz3_I327P,PSD95pdz3_327,PSD95pdz3,PSD95pdz3,P31016,0.0155168,NO,327,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.63,-3.786,2.156,5.7413,,,,,14.0388,,,,PHH,-1.50167,0.0758425,0.000998774,0.0155168 beta-lactamase_2500_V260P,beta-lactamase_2500_260,TEM-1,beta-lactamase_2500,P62593,0.0159633,NO,260,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.361275,0.00471757,0.0159633 beta-lactamase_156_A246K,beta-lactamase_156_246,TEM-1,beta-lactamase_156,P62593,0.0160676,NO,246,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.121,-3.849,1.728,,0.01,E,B,0.46,-1.01,1.959,,73.78,HHH,-1.55633,0.111618,0.00569458,0.0160676 PSD95pdz3_F325R,PSD95pdz3_325,PSD95pdz3,PSD95pdz3,P31016,0.0160777,NO,325,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.524,-3.84,2.316,5.50654,,,,,12.7236,,,,OHP,-1.314,0.0758425,0.00102273,0.0160777 kka2_1:2_T73P,kka2_1:2_73,Kka2,kka2_1:2,P00552,0.0161926,NO,73,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.51,-4.057,1.547,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.295029,0.00628605,0.0161926 kka2_1:4_G233Q,kka2_1:4_233,Kka2,kka2_1:4,P00552,0.0162691,NO,233,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.748,-4.098,3.35,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.168804,0.00232366,0.0162691 beta-lactamase_39_K71P,beta-lactamase_39_71,TEM-1,beta-lactamase_39,P62593,0.0164532,NO,71,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-0.8,-3.655,2.855,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.0495842,0.00103192,0.0164532 beta-lactamase_39_K232L,beta-lactamase_39_232,TEM-1,beta-lactamase_39,P62593,0.0166683,NO,232,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.012,-3.401,2.389,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.0495842,0.00313441,0.0166683 beta-lactamase_39_I258R,beta-lactamase_39_258,TEM-1,beta-lactamase_39,P62593,0.0168797,NO,258,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.0495842,0.007931,0.0168797 beta-lactamase_2500_I258Q,beta-lactamase_2500_258,TEM-1,beta-lactamase_2500,P62593,0.0170122,NO,258,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.361275,0.007931,0.0170122 beta-lactamase_A133D,beta-lactamase_133,TEM-1,beta-lactamase,P62593,0.017029,NO,133,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.186,-3.675,2.489,4.86423,,H,A,0.55,-0.86,2.649,,67.83,HHP,-0.988333,0.221079,0.00468022,0.017029 beta-lactamase_L205G,beta-lactamase_205,TEM-1,beta-lactamase,P62593,0.0173074,NO,205,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.922,-3.783,2.861,5.67023,,H,A,1.3,-0.46,0.678,,42.31,PHH,-1.57767,0.221079,0.00255802,0.0173074 beta-lactamase_39_E164M,beta-lactamase_39_164,TEM-1,beta-lactamase_39,P62593,0.017488,NO,164,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-0.948,-4.749,3.801,,0.011,T,B,1.04,-0.4,0.664,,64.69,HAO,-1.388,0.0495842,0.00137286,0.017488 beta-lactamase_625_L136D,beta-lactamase_625_136,TEM-1,beta-lactamase_625,P62593,0.017608,NO,136,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.232,-4.137,2.905,,,H,A,0.55,-0.34,0.336,,48.95,HHH,-1.088,0.213352,0.00442304,0.017608 beta-lactamase_2500_G249P,beta-lactamase_2500_249,TEM-1,beta-lactamase_2500,P62593,0.0176104,NO,249,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.312,-2.663,1.351,,0.256,S,B,0.23,0.04,30.841,30.841,72.73,HOO,-1.81367,0.361275,0.00220169,0.0176104 kka2_1:2_A34W,kka2_1:2_34,Kka2,kka2_1:2,P00552,0.0176113,NO,34,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.928,-5.383,4.455,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.295029,0.00343484,0.0176113 kka2_1:4_L123W,kka2_1:4_123,Kka2,kka2_1:4,P00552,0.0176776,NO,123,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.888,-5.165,4.277,,0.007,H,A,0.55,-0.4,1.447,,48.86,BHB,-1.301,0.168804,0.00325188,0.0176776 kka2_1:1_P249M,kka2_1:1_249,Kka2,kka2_1:1,P00552,0.0178294,NO,249,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.867,-3.186,1.319,,0.406,.,B,0.52,-0.01,8.037,8.037,92.05,HOA,-1.66867,0.520039,0.011045,0.0178294 WW_domain_H192P,WW_domain_192,Yap65,WW_domain,P46937,0.0178959,NO,192,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-1.739,-3.916,2.177,5.20314,,,,,,1.458,,78.57,PBH,-1.75033,0.153962,0.00436368,0.0178959 beta-lactamase_2500_C121P,beta-lactamase_2500_121,TEM-1,beta-lactamase_2500,P62593,0.0179249,NO,121,C,P,CP,Special,Special,5.07,6.3,1.23,169,121,115,-6,108.5,112.7,4.2,-0.953,-4.102,3.149,,,H,A,0.46,-0.81,1.174,,63.29,HOP,-1.46767,0.361275,0.000744322,0.0179249 beta-lactamase_39_C121K,beta-lactamase_39_121,TEM-1,beta-lactamase_39,P62593,0.0179973,NO,121,C,K,CK,Special,PositiveCharge,5.07,9.74,4.67,202,121,146,25,108.5,168.6,60.1,-0.953,-3.72,2.767,,,H,A,0.46,-0.81,7.644,,63.29,HOP,-1.46767,0.0495842,0.000744322,0.0179973 kka2_1:1_A79Y,kka2_1:1_79,Kka2,kka2_1:1,P00552,0.0180259,NO,79,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.368,-4.411,2.043,,0.563,.,B,0.46,-0.43,7.792,7.792,71.59,HHH,-1.752,0.520039,0.00664821,0.0180259 beta-lactamase_D129G,beta-lactamase_129,TEM-1,beta-lactamase,P62593,0.0181477,NO,129,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.816,-3.182,2.366,4.84204,,,B,1.33,-0.69,0.548,,34.97,PAP,-0.818,0.221079,0.00109178,0.0181477 beta-lactamase_G234T,beta-lactamase_234,TEM-1,beta-lactamase,P62593,0.0181903,NO,234,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.62,-3.646,3.026,4.24221,0.023,E,B,0.46,-0.86,,,,POH,-1.25733,0.221079,0.000889577,0.0181903 kka2_1:4_G30N,kka2_1:4_30,Kka2,kka2_1:4,P00552,0.018206,NO,30,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.596,-3.476,2.88,,0.54,S,g,0.29,3.76,,,,HOO,-1.51133,0.168804,0.00159208,0.018206 beta-lactamase_2500_A132L,beta-lactamase_2500_132,TEM-1,beta-lactamase_2500,P62593,0.0183568,NO,132,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.9,-3.146,2.246,,,H,A,0.46,-0.93,8.408,,64.69,PHH,-1.138,0.361275,0.000962524,0.0183568 beta-lactamase_2500_S68P,beta-lactamase_2500_68,TEM-1,beta-lactamase_2500,P62593,0.018601,NO,68,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-0.913,-3.704,2.791,,0.064,G,A,0.27,-1.03,2.824,,64.69,HPP,-1.37233,0.361275,0.000800065,0.018601 kka2_1:8_A215N,kka2_1:8_215,Kka2,kka2_1:8,P00552,0.018721,NO,215,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.968,-3.769,2.801,,0.039,E,B,1.04,-0.59,2.77,,50.38,HHA,-1.00467,0.100394,0.00529129,0.018721 kka2_1:8_A215N,kka2_1:8_215,Kka2,kka2_1:8,P00552,0.018721,NO,215,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.968,-3.769,2.801,,0.039,E,B,1.04,-0.59,2.77,,50.38,HHA,-1.00467,0.100394,0.00529129,0.018721 beta-lactamase_625_E164K,beta-lactamase_625_164,TEM-1,beta-lactamase_625,P62593,0.0187233,NO,164,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-0.948,-2.425,1.477,,0.011,T,B,1.04,-0.4,1.321,,64.69,HAO,-1.388,0.213352,0.00137286,0.0187233 kka2_1:4_L232A,kka2_1:4_232,Kka2,kka2_1:4,P00552,0.0188033,NO,232,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.514,-3.306,1.792,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.168804,0.00800103,0.0188033 kka2_1:2_F203P,kka2_1:2_203,Kka2,kka2_1:2,P00552,0.0188864,NO,203,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-0.911,-4.356,3.445,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.295029,0.00318738,0.0188864 beta-lactamase_39_G234P,beta-lactamase_39_234,TEM-1,beta-lactamase_39,P62593,0.0189749,NO,234,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.62,-3.88,3.26,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.0495842,0.000889577,0.0189749 kka2_1:1_V80S,kka2_1:1_80,Kka2,kka2_1:1,P00552,0.0190268,NO,80,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.144,-3.612,2.468,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.520039,0.00488211,0.0190268 beta-lactamase_2500_D174P,beta-lactamase_2500_174,TEM-1,beta-lactamase_2500,P62593,0.019083,NO,174,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.738,-3.655,2.917,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.361275,0.00125633,0.019083 beta-lactamase_156_I261K,beta-lactamase_156_261,TEM-1,beta-lactamase_156,P62593,0.0190937,NO,261,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.111618,0.0123091,0.0190937 kka2_1:4_V75D,kka2_1:4_75,Kka2,kka2_1:4,P00552,0.0192075,NO,75,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-2.06,-4.066,2.006,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.168804,0.00693733,0.0192075 beta-lactamase_A132V,beta-lactamase_132,TEM-1,beta-lactamase,P62593,0.0194566,NO,132,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.9,-2.46,1.56,4.58504,,H,A,2.34,-0.93,2.217,,64.69,PHH,-1.138,0.221079,0.000962524,0.0194566 beta-lactamase_G43V,beta-lactamase_43,TEM-1,beta-lactamase,P62593,0.0195894,NO,43,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.62,-3.754,3.134,5.28886,,E,B,0.77,-0.78,,,,HOH,-1.577,0.221079,0.00120151,0.0195894 beta-lactamase_G234V,beta-lactamase_234,TEM-1,beta-lactamase,P62593,0.0196602,NO,234,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.62,-3.754,3.134,4.24221,0.023,E,B,0.46,-0.86,,,,POH,-1.25733,0.221079,0.000889577,0.0196602 beta-lactamase_F70P,beta-lactamase_70,TEM-1,beta-lactamase,P62593,0.019893,NO,70,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.169,-4.211,3.042,5.42055,,H,A,1.1,-1.34,1.14,,63.99,PHB,-0.980667,0.221079,0.00193499,0.019893 beta-lactamase_I278D,beta-lactamase_278,TEM-1,beta-lactamase,P62593,0.019893,NO,278,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.348,-3.998,2.65,5.35127,0.015,H,A,0.77,-0.85,2.718,,63.29,AHO,-1.41833,0.221079,0.0310297,0.019893 beta-lactamase_V42K,beta-lactamase_42,TEM-1,beta-lactamase,P62593,0.019893,NO,42,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.564,-3.817,2.253,5.27904,0.017,E,B,1.64,-0.51,2.024,,63.99,BHO,-1.042,0.221079,0.00404515,0.019893 kka2_1:2_L232A,kka2_1:2_232,Kka2,kka2_1:2,P00552,0.0199705,NO,232,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.514,-3.306,1.792,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.295029,0.00800103,0.0199705 kka2_1:2_G189W,kka2_1:2_189,Kka2,kka2_1:2,P00552,0.02007,NO,189,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.596,-5.126,4.53,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.295029,0.00253688,0.02007 Pab1_K156P,Pab1_156,Pab1,Pab1,P04147,0.0203591,NO,156,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.083,-3.472,2.389,,0.406,E,B,1.82,-0.26,,,,PBH,-1.58167,0.175299,0.000316767,0.0203591 beta-lactamase_625_V31Y,beta-lactamase_625_31,TEM-1,beta-lactamase_625,P62593,0.0203933,NO,31,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.822,-4.027,2.205,,,H,A,0.44,-0.46,2.576,,73.78,BHB,-2.03767,0.213352,0.00478065,0.0203933 beta-lactamase_2500_D155Q,beta-lactamase_2500_155,TEM-1,beta-lactamase_2500,P62593,0.0204693,NO,155,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.889,-3.667,2.778,,0.049,,B,0.75,-0.9,2.386,,64.69,OAB,-1.62267,0.361275,0.00135315,0.0204693 kka2_1:4_G189H,kka2_1:4_189,Kka2,kka2_1:4,P00552,0.0205094,NO,189,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.596,-4.708,4.112,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.168804,0.00253688,0.0205094 beta-lactamase_T179P,beta-lactamase_179,TEM-1,beta-lactamase,P62593,0.020615,NO,179,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.085,-3.739,2.654,5.07116,,E,B,0.8,-1.38,1.859,,73.08,PPH,-1.557,0.221079,0.00226045,0.020615 kka2_1:1_N195A,kka2_1:1_195,Kka2,kka2_1:1,P00552,0.0206276,NO,195,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-0.836,-3.354,2.518,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.520039,0.00276134,0.0206276 beta-lactamase_625_D177F,beta-lactamase_625_177,TEM-1,beta-lactamase_625,P62593,0.0209568,NO,177,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.967,-4.34,3.373,,0.006,T,L,0.75,-1.02,1.333,,64.69,BAP,-0.873667,0.213352,0.000864022,0.0209568 beta-lactamase_625_I261D,beta-lactamase_625_261,TEM-1,beta-lactamase_625,P62593,0.0211679,NO,261,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.213352,0.0123091,0.0211679 beta-lactamase_39_S68W,beta-lactamase_39_68,TEM-1,beta-lactamase_39,P62593,0.0212138,NO,68,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-0.913,-5.371,4.458,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.0495842,0.000800065,0.0212138 kka2_1:8_A222N,kka2_1:8_222,Kka2,kka2_1:8,P00552,0.0213214,NO,222,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.725,-3.926,3.201,,,H,A,1.04,-1.21,,,,HHH,-1.10833,0.100394,0.00207657,0.0213214 kka2_1:8_A222N,kka2_1:8_222,Kka2,kka2_1:8,P00552,0.0213214,NO,222,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.725,-3.926,3.201,,,H,A,1.04,-1.21,,,,HHH,-1.10833,0.100394,0.00207657,0.0213214 kka2_1:4_T187I,kka2_1:4_187,Kka2,kka2_1:4,P00552,0.0214057,NO,187,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.273,-2.925,1.652,,0.007,E,B,0.22,-0.85,2.73,,52.27,HPB,-1.06567,0.168804,0.00693073,0.0214057 kka2_1:1_V80F,kka2_1:1_80,Kka2,kka2_1:1,P00552,0.0216911,NO,80,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.144,-3.963,2.819,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.520039,0.00488211,0.0216911 beta-lactamase_625_M209D,beta-lactamase_625_209,TEM-1,beta-lactamase_625,P62593,0.021744,NO,209,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.442,-4.067,2.625,,,H,A,0.55,-0.97,1.167,,64.69,HHA,-1.52633,0.213352,0.00625021,0.021744 kka2_1:1_P76W,kka2_1:1_76,Kka2,kka2_1:1,P00552,0.0219375,NO,76,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.449,-5.603,4.154,,0.331,.,B,0.52,-0.41,0.345,,63.64,HOO,-1.662,0.520039,0.00625685,0.0219375 beta-lactamase_2500_G243L,beta-lactamase_2500_243,TEM-1,beta-lactamase_2500,P62593,0.0219652,NO,243,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.361275,0.00464034,0.0219652 kka2_1:8_D190I,kka2_1:8_190,Kka2,kka2_1:8,P00552,0.0219683,NO,190,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.708,-4.039,3.331,,0.213,S,b,0.29,-0.82,,,,OAH,-0.711667,0.100394,0.00247989,0.0219683 kka2_1:8_D190I,kka2_1:8_190,Kka2,kka2_1:8,P00552,0.0219683,NO,190,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.708,-4.039,3.331,,0.213,S,b,0.29,-0.82,,,,OAH,-0.711667,0.100394,0.00247989,0.0219683 kka2_1:8_G245Y,kka2_1:8_245,Kka2,kka2_1:8,P00552,0.0219683,NO,245,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.812,-4.419,3.607,,0.655,T,g,0.75,0.03,1.148,,65.53,HOH,-1.19833,0.100394,0.00683899,0.0219683 kka2_1:8_G245Y,kka2_1:8_245,Kka2,kka2_1:8,P00552,0.0219683,NO,245,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.812,-4.419,3.607,,0.655,T,g,0.75,0.03,1.148,,65.53,HOH,-1.19833,0.100394,0.00683899,0.0219683 kka2_1:8_M120S,kka2_1:8_120,Kka2,kka2_1:8,P00552,0.0219683,NO,120,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-3.877,-3.662,-0.215,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.100394,0.00265808,0.0219683 kka2_1:8_M120S,kka2_1:8_120,Kka2,kka2_1:8,P00552,0.0219683,NO,120,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-3.877,-3.662,-0.215,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.100394,0.00265808,0.0219683 beta-lactamase_625_D155K,beta-lactamase_625_155,TEM-1,beta-lactamase_625,P62593,0.0220007,NO,155,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.889,-3.426,2.537,,0.049,,B,0.75,-0.9,4.922,,64.69,OAB,-1.62267,0.213352,0.00135315,0.0220007 beta-lactamase_G43L,beta-lactamase_43,TEM-1,beta-lactamase,P62593,0.0220409,NO,43,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.62,-3.808,3.188,5.28886,,E,B,0.77,-0.78,,,,HOH,-1.577,0.221079,0.00120151,0.0220409 beta-lactamase_K232G,beta-lactamase_232,TEM-1,beta-lactamase,P62593,0.0221337,NO,232,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.012,-3.401,2.389,5.18286,,E,B,2.92,-1.1,1.174,,65.03,ABP,-1.238,0.221079,0.00313441,0.0221337 beta-lactamase_0_T126Q,beta-lactamase_0_126,TEM-1,beta-lactamase_0,P62593,0.0222295,NO,126,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.122,-3.945,2.823,,0.05,H,A,0.22,-0.05,0.705,,44.41,HPH,-1.60467,0.0500837,0.00244552,0.0222295 kka2_1:8_E262Y,kka2_1:8_262,Kka2,kka2_1:8,P00552,0.0222913,NO,262,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-0.829,-4.189,3.36,,0.059,G,A,1.52,-0.18,0.837,,42.42,AAH,-0.816,0.100394,0.0191586,0.0222913 kka2_1:8_E262Y,kka2_1:8_262,Kka2,kka2_1:8,P00552,0.0222913,NO,262,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-0.829,-4.189,3.36,,0.059,G,A,1.52,-0.18,0.837,,42.42,AAH,-0.816,0.100394,0.0191586,0.0222913 beta-lactamase_156_I261D,beta-lactamase_156_261,TEM-1,beta-lactamase_156,P62593,0.022519,NO,261,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.111618,0.0123091,0.022519 kka2_1:1_A78I,kka2_1:1_78,Kka2,kka2_1:1,P00552,0.0226058,NO,78,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.744,-3.934,2.19,,0.078,.,B,0.46,-0.53,0.206,,56.06,OHH,-1.863,0.520039,0.00457299,0.0226058 beta-lactamase_39_A132L,beta-lactamase_39_132,TEM-1,beta-lactamase_39,P62593,0.0227618,NO,132,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.9,-3.146,2.246,,,H,A,0.46,-0.93,8.408,,64.69,PHH,-1.138,0.0495842,0.000962524,0.0227618 kka2_1:8_A191I,kka2_1:8_191,Kka2,kka2_1:8,P00552,0.0229363,NO,191,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.831,-3.676,2.845,,,,b,1.04,-0.94,1.306,,50,AHO,-0.868667,0.100394,0.00338807,0.0229363 kka2_1:8_A191I,kka2_1:8_191,Kka2,kka2_1:8,P00552,0.0229363,NO,191,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.831,-3.676,2.845,,,,b,1.04,-0.94,1.306,,50,AHO,-0.868667,0.100394,0.00338807,0.0229363 beta-lactamase_2500_F64R,beta-lactamase_2500_64,TEM-1,beta-lactamase_2500,P62593,0.0230054,NO,64,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-0.841,-4.158,3.317,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.361275,0.000947691,0.0230054 beta-lactamase_625_Y44N,beta-lactamase_625_44,TEM-1,beta-lactamase_625,P62593,0.0231634,NO,44,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-2.547,-4.162,1.615,,,E,B,0.21,-0.45,2.371,,73.78,OHH,-1.86267,0.213352,0.00426364,0.0231634 kka2_1:8_G30E,kka2_1:8_30,Kka2,kka2_1:8,P00552,0.0232583,NO,30,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.596,-3.693,3.097,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.100394,0.00159208,0.0232583 kka2_1:8_G30E,kka2_1:8_30,Kka2,kka2_1:8,P00552,0.0232583,NO,30,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.596,-3.693,3.097,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.100394,0.00159208,0.0232583 beta-lactamase_625_V42E,beta-lactamase_625_42,TEM-1,beta-lactamase_625,P62593,0.0233034,NO,42,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.564,-3.88,2.316,,0.017,E,B,0.44,-0.51,2.576,,63.99,BHO,-1.042,0.213352,0.00404515,0.0233034 beta-lactamase_2500_C121E,beta-lactamase_2500_121,TEM-1,beta-lactamase_2500,P62593,0.0233559,NO,121,C,E,CE,Special,negativeCharge,5.07,3.22,-1.85,170,121,147,26,108.5,138.4,29.9,-0.953,-3.987,3.034,,,H,A,0.46,-0.81,1.174,,63.29,HOP,-1.46767,0.361275,0.000744322,0.0233559 beta-lactamase_G248L,beta-lactamase_248,TEM-1,beta-lactamase,P62593,0.0233835,NO,248,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.794,-3.512,1.718,4.69798,,E,b,0.23,-0.43,1.782,,61.19,HOO,-1.52867,0.221079,0.00428493,0.0233835 beta-lactamase_625_A185K,beta-lactamase_625_185,TEM-1,beta-lactamase_625,P62593,0.023456,NO,185,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.406,-3.666,2.26,,,H,A,0.46,-1.02,0.365,,65.03,HHP,-1.84033,0.213352,0.00467449,0.023456 beta-lactamase_156_I245K,beta-lactamase_156_245,TEM-1,beta-lactamase_156,P62593,0.0235082,NO,245,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.111618,0.00391032,0.0235082 kka2_1:2_G30E,kka2_1:2_30,Kka2,kka2_1:2,P00552,0.0236425,NO,30,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.596,-3.693,3.097,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.295029,0.00159208,0.0236425 kka2_1:2_L241G,kka2_1:2_241,Kka2,kka2_1:2,P00552,0.0236756,NO,241,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.158,-3.805,2.647,,0.08,H,A,0.55,-0.82,1.598,,63.26,HHH,-1.58533,0.295029,0.0117299,0.0236756 beta-lactamase_39_S68L,beta-lactamase_39_68,TEM-1,beta-lactamase_39,P62593,0.0237552,NO,68,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-0.913,-3.407,2.494,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.0495842,0.000800065,0.0237552 beta-lactamase_39_E164I,beta-lactamase_39_164,TEM-1,beta-lactamase_39,P62593,0.0237791,NO,164,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-0.948,-4.08,3.132,,0.011,T,B,1.04,-0.4,0.664,,64.69,HAO,-1.388,0.0495842,0.00137286,0.0237791 beta-lactamase_G234R,beta-lactamase_234,TEM-1,beta-lactamase,P62593,0.0237892,NO,234,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.62,-3.933,3.313,4.24221,0.023,E,B,0.46,-0.86,,,,POH,-1.25733,0.221079,0.000889577,0.0237892 kka2_1:1_L193I,kka2_1:1_193,Kka2,kka2_1:1,P00552,0.0241845,NO,193,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.983,-3.143,2.16,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.520039,0.00480179,0.0241845 Ubiquitin_H68L,Ubiquitin_68,Uba1,Ubiquitin,P0CG48,0.0241935,NO,68,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-1.869,-2.803,0.934,4.81902,0.194,E,B,0.72,-1.02,21.325,21.325,65.11,HBH,-1.583,0.205827,0.000925438,0.0241935 beta-lactamase_39_L136W,beta-lactamase_39_136,TEM-1,beta-lactamase_39,P62593,0.024249,NO,136,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.232,-5.281,4.049,,,H,A,0.55,-0.34,0.336,,48.95,HHH,-1.088,0.0495842,0.00442304,0.024249 kka2_1:4_P194W,kka2_1:4_194,Kka2,kka2_1:4,P00552,0.0242914,NO,194,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.846,-5.598,4.752,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.168804,0.00314194,0.0242914 kka2_1:4_W91P,kka2_1:4_91,Kka2,kka2_1:4,P00552,0.0243295,NO,91,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-1.178,-4.336,3.158,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.168804,0.00358653,0.0243295 beta-lactamase_K232E,beta-lactamase_232,TEM-1,beta-lactamase,P62593,0.0245468,NO,232,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.012,-3.087,2.075,5.18286,,E,B,2.92,-1.1,1.174,,65.03,ABP,-1.238,0.221079,0.00313441,0.0245468 beta-lactamase_39_S68K,beta-lactamase_39_68,TEM-1,beta-lactamase_39,P62593,0.0246355,NO,68,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-0.913,-3.258,2.345,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.0495842,0.000800065,0.0246355 beta-lactamase_39_L136Y,beta-lactamase_39_136,TEM-1,beta-lactamase_39,P62593,0.0247132,NO,136,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.232,-4.051,2.819,,,H,A,0.55,-0.34,0.336,,48.95,HHH,-1.088,0.0495842,0.00442304,0.0247132 kka2_1:4_R253F,kka2_1:4_253,Kka2,kka2_1:4,P00552,0.0247251,NO,253,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.356,-4.389,3.033,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.168804,0.0144195,0.0247251 beta-lactamase_2500_C75H,beta-lactamase_2500_75,TEM-1,beta-lactamase_2500,P62593,0.0248146,NO,75,C,H,CH,Special,PositiveCharge,5.07,7.59,2.52,174,121,155,34,108.5,153.2,44.7,-1.245,-4.871,3.626,,,H,A,0.46,-0.87,0.844,,50,HOO,-1.24333,0.361275,0.0034616,0.0248146 kka2_1:1_A237G,kka2_1:1_237,Kka2,kka2_1:1,P00552,0.0250918,NO,237,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.12,-3.628,1.508,,0.068,H,A,0.46,-0.71,2.369,,92.05,HHA,-2.10433,0.520039,0.012257,0.0250918 beta-lactamase_2500_G43T,beta-lactamase_2500_43,TEM-1,beta-lactamase_2500,P62593,0.0251224,NO,43,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.62,-3.646,3.026,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.361275,0.00120151,0.0251224 beta-lactamase_2500_T69R,beta-lactamase_2500_69,TEM-1,beta-lactamase_2500,P62593,0.0251549,NO,69,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-0.973,-3.768,2.795,,,G,A,0.22,-1.24,2.05,,93.01,PPH,-1.01833,0.361275,0.00127498,0.0251549 beta-lactamase_M184R,beta-lactamase_184,TEM-1,beta-lactamase,P62593,0.0253415,NO,184,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.593,-3.928,2.335,5.39575,,H,A,1.3,-0.87,2.893,,62.94,HHH,-1.41,0.221079,0.00356019,0.0253415 kka2_1:4_Y257N,kka2_1:4_257,Kka2,kka2_1:4,P00552,0.0255882,NO,257,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-1.064,-4.053,2.989,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.168804,0.0148191,0.0255882 beta-lactamase_L136F,beta-lactamase_136,TEM-1,beta-lactamase,P62593,0.025615,NO,136,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.232,-3.77,2.538,5.31114,,H,A,2.89,-0.34,1.539,,48.95,HHH,-1.088,0.221079,0.00442304,0.025615 beta-lactamase_39_R257P,beta-lactamase_39_257,TEM-1,beta-lactamase_39,P62593,0.0256386,NO,257,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.0495842,0.00756629,0.0256386 beta-lactamase_156_V42E,beta-lactamase_156_42,TEM-1,beta-lactamase_156,P62593,0.0256942,NO,42,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.564,-3.88,2.316,,0.017,E,B,0.44,-0.51,2.576,,63.99,BHO,-1.042,0.111618,0.00404515,0.0256942 beta-lactamase_M66R,beta-lactamase_66,TEM-1,beta-lactamase,P62593,0.0259043,NO,66,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.362,-3.923,2.561,5.29561,0.013,,A,1.3,-0.7,1.319,,73.08,OHH,-1.49567,0.221079,0.00412876,0.0259043 beta-lactamase_G76R,beta-lactamase_76,TEM-1,beta-lactamase,P62593,0.0259632,NO,76,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.189,-3.905,2.716,4.73862,,H,A,2.05,-0.67,3.059,,67.83,OOH,-1.22267,0.221079,0.00476637,0.0259632 beta-lactamase_39_V260K,beta-lactamase_39_260,TEM-1,beta-lactamase_39,P62593,0.0260709,NO,260,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.0495842,0.00471757,0.0260709 kka2_1:4_G189W,kka2_1:4_189,Kka2,kka2_1:4,P00552,0.0260982,NO,189,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.596,-5.126,4.53,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.168804,0.00253688,0.0260982 kka2_1:8_M197N,kka2_1:8_197,Kka2,kka2_1:8,P00552,0.0264613,NO,197,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.707,-4.155,2.448,,0.121,E,B,1.59,-1.19,4.408,,65.53,HHH,-1.847,0.100394,0.00921295,0.0264613 kka2_1:8_M197N,kka2_1:8_197,Kka2,kka2_1:8,P00552,0.0264613,NO,197,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.707,-4.155,2.448,,0.121,E,B,1.59,-1.19,4.408,,65.53,HHH,-1.847,0.100394,0.00921295,0.0264613 kka2_1:4_F240I,kka2_1:4_240,Kka2,kka2_1:4,P00552,0.026506,NO,240,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-0.911,-3.319,2.408,,,H,A,0.58,-1.21,5.798,,50.38,BHH,-1.67267,0.168804,0.00552543,0.026506 beta-lactamase_D155R,beta-lactamase_155,TEM-1,beta-lactamase,P62593,0.0268739,NO,155,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.889,-3.873,2.984,4.92265,0.049,,B,0.45,-0.9,3.208,,64.69,OAB,-1.62267,0.221079,0.00135315,0.0268739 beta-lactamase_I256H,beta-lactamase_256,TEM-1,beta-lactamase,P62593,0.0268739,NO,256,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.621,-4.999,3.378,5.3196,,E,B,1,-0.84,1.615,,73.08,BHH,-1.80667,0.221079,0.00710634,0.0268739 beta-lactamase_625_K71E,beta-lactamase_625_71,TEM-1,beta-lactamase_625,P62593,0.0268859,NO,71,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-0.8,-2.99,2.19,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.213352,0.00103192,0.0268859 Pab1_G150Y,Pab1_150,Pab1,Pab1,P04147,0.0271836,NO,150,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.809,-4.205,3.396,,0.287,S,b,0.23,0.53,,,,HOA,-1.45233,0.175299,0.000323835,0.0271836 beta-lactamase_A246P,beta-lactamase_246,TEM-1,beta-lactamase,P62593,0.0275085,NO,246,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.121,-4.126,2.005,4.78979,0.01,E,B,0.52,-1.01,1.26,,73.78,HHH,-1.55633,0.221079,0.00569458,0.0275085 beta-lactamase_N130F,beta-lactamase_130,TEM-1,beta-lactamase,P62593,0.0275085,NO,130,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-0.798,-4.292,3.494,5.26686,0.069,H,A,1.08,-0.74,,,,APP,-0.980667,0.221079,0.000683376,0.0275085 beta-lactamase_Y260K,beta-lactamase_260,TEM-1,beta-lactamase,P62593,0.0275085,NO,260,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-1.101,-3.796,2.695,5.50878,,E,B,0.73,-1.04,0.865,,60.49,HHP,-1.83433,0.221079,0.00471757,0.0275085 beta-lactamase_39_V260H,beta-lactamase_39_260,TEM-1,beta-lactamase_39,P62593,0.0276028,NO,260,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.0495842,0.00471757,0.0276028 kka2_1:2_V214P,kka2_1:2_214,Kka2,kka2_1:2,P00552,0.0278402,NO,214,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.261,-4.14,2.879,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.295029,0.00692782,0.0278402 kka2_1:2_W236I,kka2_1:2_236,Kka2,kka2_1:2,P00552,0.0278664,NO,236,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-1.363,-3.761,2.398,,0.303,H,A,1.51,-0.76,5.58,,48.48,AHH,-1.81267,0.295029,0.0088796,0.0278664 beta-lactamase_625_E164I,beta-lactamase_625_164,TEM-1,beta-lactamase_625,P62593,0.027956,NO,164,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-0.948,-4.08,3.132,,0.011,T,B,1.04,-0.4,1.321,,64.69,HAO,-1.388,0.213352,0.00137286,0.027956 beta-lactamase_625_G43Q,beta-lactamase_625_43,TEM-1,beta-lactamase_625,P62593,0.0284558,NO,43,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.62,-4.124,3.504,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.213352,0.00120151,0.0284558 PSD95pdz3_G324P,PSD95pdz3_324,PSD95pdz3,PSD95pdz3,P31016,0.0286033,NO,324,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.008,-3.561,2.553,4.98881,,,,,10.4525,,,,HOH,-1.293,0.0758425,0.00103462,0.0286033 beta-lactamase_A123P,beta-lactamase_123,TEM-1,beta-lactamase,P62593,0.028619,NO,123,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.834,-3.704,2.87,4.70061,0.039,H,A,0.52,-0.72,0.705,,41.26,PHH,-1.47367,0.221079,0.0010157,0.028619 beta-lactamase_K71H,beta-lactamase_71,TEM-1,beta-lactamase,P62593,0.028619,NO,71,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-0.8,-4.455,3.655,5.15697,,H,A,1.3,-0.99,,,,HBH,-1.209,0.221079,0.00103192,0.028619 beta-lactamase_L79K,beta-lactamase_79,TEM-1,beta-lactamase,P62593,0.028619,NO,79,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.842,-3.679,2.837,4.98681,0.007,H,A,1.07,-0.16,0.823,,50.35,HHP,-1.44333,0.221079,0.000947397,0.028619 beta-lactamase_P181E,beta-lactamase_181,TEM-1,beta-lactamase,P62593,0.028619,NO,181,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.813,-3.466,2.653,5.14752,,H,A,1.1,-1.14,1.357,,61.54,HOH,-1.795,0.221079,0.000703122,0.028619 beta-lactamase_0_V117E,beta-lactamase_0_117,TEM-1,beta-lactamase_0,P62593,0.0287217,NO,117,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.53,-3.909,2.379,,,H,A,0.44,-0.34,1.16,,65.03,PHB,-1.741,0.0500837,0.00467906,0.0287217 beta-lactamase_39_D129M,beta-lactamase_39_129,TEM-1,beta-lactamase_39,P62593,0.0288393,NO,129,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.816,-4.927,4.111,,,,B,0.75,-0.69,0.56,,34.97,PAP,-0.818,0.0495842,0.00109178,0.0288393 beta-lactamase_156_K71C,beta-lactamase_156_71,TEM-1,beta-lactamase_156,P62593,0.0288519,NO,71,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-0.8,-5.087,4.287,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.111618,0.00103192,0.0288519 beta-lactamase_625_L136F,beta-lactamase_625_136,TEM-1,beta-lactamase_625,P62593,0.0289109,NO,136,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.232,-3.77,2.538,,,H,A,0.55,-0.34,0.336,,48.95,HHH,-1.088,0.213352,0.00442304,0.0289109 kka2_1:8_G213Y,kka2_1:8_213,Kka2,kka2_1:8,P00552,0.0290013,NO,213,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.596,-4.416,3.82,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.100394,0.00187654,0.0290013 kka2_1:8_G213Y,kka2_1:8_213,Kka2,kka2_1:8,P00552,0.0290013,NO,213,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.596,-4.416,3.82,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.100394,0.00187654,0.0290013 kka2_1:2_D183L,kka2_1:2_183,Kka2,kka2_1:2,P00552,0.0290044,NO,183,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.204,-3.71,2.506,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.295029,0.00426304,0.0290044 beta-lactamase_L146R,beta-lactamase_146,TEM-1,beta-lactamase,P62593,0.0290763,NO,146,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.462,-4.192,2.73,5.62483,0.007,H,A,1.3,-0.56,1.953,,64.69,AHP,-1.656,0.221079,0.00474542,0.0290763 kka2_1:2_G213Q,kka2_1:2_213,Kka2,kka2_1:2,P00552,0.0290978,NO,213,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.596,-4.153,3.557,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.295029,0.00187654,0.0290978 beta-lactamase_625_T158K,beta-lactamase_625_158,TEM-1,beta-lactamase_625,P62593,0.0291475,NO,158,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.116,-3.466,2.35,,0.036,,B,0.22,-0.85,3.771,,69.58,HPB,-1.269,0.213352,0.00341825,0.0291475 beta-lactamase_39_G243R,beta-lactamase_39_243,TEM-1,beta-lactamase_39,P62593,0.0291736,NO,243,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.0495842,0.00464034,0.0291736 kka2_1:2_G213S,kka2_1:2_213,Kka2,kka2_1:2,P00552,0.029346,NO,213,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.596,-3.189,2.593,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.295029,0.00187654,0.029346 beta-lactamase_39_E164W,beta-lactamase_39_164,TEM-1,beta-lactamase_39,P62593,0.0294192,NO,164,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-0.948,-5.346,4.398,,0.011,T,B,1.04,-0.4,0.664,,64.69,HAO,-1.388,0.0495842,0.00137286,0.0294192 kka2_1:2_G189H,kka2_1:2_189,Kka2,kka2_1:2,P00552,0.0295065,NO,189,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.596,-4.708,4.112,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.295029,0.00253688,0.0295065 beta-lactamase_156_A133M,beta-lactamase_156_133,TEM-1,beta-lactamase_156,P62593,0.0295848,NO,133,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.186,-4.694,3.508,,,H,A,0.46,-0.86,0.805,,67.83,HHP,-0.988333,0.111618,0.00468022,0.0295848 kka2_1:8_L126S,kka2_1:8_126,Kka2,kka2_1:8,P00552,0.0299488,NO,126,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.246,-3.666,2.42,,0.285,S,B,1.59,0.12,4.443,,51.89,PHA,-1.744,0.100394,0.0066485,0.0299488 kka2_1:8_L126S,kka2_1:8_126,Kka2,kka2_1:8,P00552,0.0299488,NO,126,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.246,-3.666,2.42,,0.285,S,B,1.59,0.12,4.443,,51.89,PHA,-1.744,0.100394,0.0066485,0.0299488 kka2_1:4_I196K,kka2_1:4_196,Kka2,kka2_1:4,P00552,0.0299578,NO,196,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-2.115,-3.976,1.861,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.168804,0.0107273,0.0299578 beta-lactamase_K232D,beta-lactamase_232,TEM-1,beta-lactamase,P62593,0.0299765,NO,232,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.012,-3.566,2.554,5.18286,,E,B,2.92,-1.1,1.174,,65.03,ABP,-1.238,0.221079,0.00313441,0.0299765 kka2_1:4_V186H,kka2_1:4_186,Kka2,kka2_1:4,P00552,0.0301399,NO,186,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.011,-4.974,3.963,,,E,B,0.44,-0.61,0.679,,45.83,HHP,-1.10967,0.168804,0.00409703,0.0301399 beta-lactamase_39_K232P,beta-lactamase_39_232,TEM-1,beta-lactamase_39,P62593,0.0301497,NO,232,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.012,-3.752,2.74,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.0495842,0.00313441,0.0301497 beta-lactamase_I278Q,beta-lactamase_278,TEM-1,beta-lactamase,P62593,0.0302126,NO,278,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.348,-4.242,2.894,5.35127,0.015,H,A,0.77,-0.85,2.718,,63.29,AHO,-1.41833,0.221079,0.0310297,0.0302126 beta-lactamase_625_E164V,beta-lactamase_625_164,TEM-1,beta-lactamase_625,P62593,0.0303475,NO,164,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-0.948,-3.599,2.651,,0.011,T,B,1.04,-0.4,1.321,,64.69,HAO,-1.388,0.213352,0.00137286,0.0303475 beta-lactamase_625_V78D,beta-lactamase_625_78,TEM-1,beta-lactamase_625,P62593,0.030563,NO,78,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.459,-4.082,2.623,,,H,A,0.44,-0.47,2.045,,63.64,HHH,-1.17833,0.213352,0.00492501,0.030563 kka2_1:1_A78K,kka2_1:1_78,Kka2,kka2_1:1,P00552,0.0306316,NO,78,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.744,-3.53,1.786,,0.078,.,B,0.46,-0.53,0.206,,56.06,OHH,-1.863,0.520039,0.00457299,0.0306316 beta-lactamase_39_K71G,beta-lactamase_39_71,TEM-1,beta-lactamase_39,P62593,0.0306731,NO,71,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-0.8,-3.358,2.558,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.0495842,0.00103192,0.0306731 beta-lactamase_0_S122D,beta-lactamase_0_122,TEM-1,beta-lactamase_0,P62593,0.030799,NO,122,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.406,-2.549,0.143,,0.352,H,A,0.27,-0.54,30.794,30.794,77.62,OPH,-1.39767,0.0500837,0.00497825,0.030799 beta-lactamase_156_S128Y,beta-lactamase_156_128,TEM-1,beta-lactamase_156,P62593,0.0308324,NO,128,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-0.84,-4.162,3.322,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.111618,0.00071483,0.0308324 kka2_1:2_V186P,kka2_1:2_186,Kka2,kka2_1:2,P00552,0.0309711,NO,186,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.011,-4.069,3.058,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.295029,0.00409703,0.0309711 beta-lactamase_0_G76Y,beta-lactamase_0_76,TEM-1,beta-lactamase_0,P62593,0.031027,NO,76,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.189,-4.36,3.171,,,H,A,0.29,-0.67,1.188,,67.83,OOH,-1.22267,0.0500837,0.00476637,0.031027 beta-lactamase_A133I,beta-lactamase_133,TEM-1,beta-lactamase,P62593,0.0310624,NO,133,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.186,-3.823,2.637,4.86423,,H,A,0.55,-0.86,2.649,,67.83,HHP,-0.988333,0.221079,0.00468022,0.0310624 beta-lactamase_Y260E,beta-lactamase_260,TEM-1,beta-lactamase,P62593,0.0310624,NO,260,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-1.101,-3.799,2.698,5.50878,,E,B,0.73,-1.04,0.865,,60.49,HHP,-1.83433,0.221079,0.00471757,0.0310624 beta-lactamase_625_G43N,beta-lactamase_625_43,TEM-1,beta-lactamase_625,P62593,0.0311493,NO,43,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.62,-3.448,2.828,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.213352,0.00120151,0.0311493 beta-lactamase_625_G43F,beta-lactamase_625_43,TEM-1,beta-lactamase_625,P62593,0.0312957,NO,43,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.62,-4.292,3.672,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.213352,0.00120151,0.0312957 kka2_1:2_L94H,kka2_1:2_94,Kka2,kka2_1:2,P00552,0.0313498,NO,94,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.618,-4.931,3.313,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.295029,0.00520888,0.0313498 beta-lactamase_625_L192P,beta-lactamase_625_192,TEM-1,beta-lactamase_625,P62593,0.0313851,NO,192,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.254,-4.129,2.875,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.213352,0.00558728,0.0313851 kka2_1:2_E96I,kka2_1:2_96,Kka2,kka2_1:2,P00552,0.0320436,NO,96,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.573,-3.722,1.149,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.295029,0.00369441,0.0320436 beta-lactamase_2500_I280G,beta-lactamase_2500_280,TEM-1,beta-lactamase_2500,P62593,0.03215,NO,280,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.361275,0.0530888,0.03215 beta-lactamase_2500_K71D,beta-lactamase_2500_71,TEM-1,beta-lactamase_2500,P62593,0.0322569,NO,71,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-0.8,-3.469,2.669,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.361275,0.00103192,0.0322569 beta-lactamase_39_K232Y,beta-lactamase_39_232,TEM-1,beta-lactamase_39,P62593,0.032267,NO,232,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.012,-4.205,3.193,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.0495842,0.00313441,0.032267 beta-lactamase_2500_R59V,beta-lactamase_2500_59,TEM-1,beta-lactamase_2500,P62593,0.0324025,NO,59,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.345,-3.76,2.415,,0.329,S,L,1.2,-0.09,3.719,,73.08,HBO,-2.24267,0.361275,0.00318082,0.0324025 beta-lactamase_625_T69D,beta-lactamase_625_69,TEM-1,beta-lactamase_625,P62593,0.0325155,NO,69,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-0.973,-3.534,2.561,,,G,A,0.22,-1.24,2.716,,93.01,PPH,-1.01833,0.213352,0.00127498,0.0325155 kka2_1:2_L92Y,kka2_1:2_92,Kka2,kka2_1:2,P00552,0.0325321,NO,92,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.893,-4.021,3.128,,0.007,E,B,1.59,-0.19,1.447,,63.26,HHH,-0.962,0.295029,0.00307177,0.0325321 kka2_1:1_L232A,kka2_1:1_232,Kka2,kka2_1:1,P00552,0.0328183,NO,232,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.514,-3.306,1.792,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.520039,0.00800103,0.0328183 beta-lactamase_625_D177K,beta-lactamase_625_177,TEM-1,beta-lactamase_625,P62593,0.0330775,NO,177,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.967,-3.523,2.556,,0.006,T,L,0.75,-1.02,1.333,,64.69,BAP,-0.873667,0.213352,0.000864022,0.0330775 kka2_1:4_A78L,kka2_1:4_78,Kka2,kka2_1:4,P00552,0.0332556,NO,78,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.744,-3.506,1.762,,0.078,.,B,0.46,-0.53,0.594,,56.06,OHH,-1.863,0.168804,0.00457299,0.0332556 beta-lactamase_2500_I125K,beta-lactamase_2500_125,TEM-1,beta-lactamase_2500,P62593,0.0333191,NO,125,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.441,-3.825,2.384,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.361275,0.00383964,0.0333191 beta-lactamase_S68P,beta-lactamase_68,TEM-1,beta-lactamase,P62593,0.0333815,NO,68,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-0.913,-3.704,2.791,4.94745,0.064,G,A,0.77,-1.03,3.202,,64.69,HPP,-1.37233,0.221079,0.000800065,0.0333815 kka2_1:8_M116S,kka2_1:8_116,Kka2,kka2_1:8,P00552,0.0333997,NO,116,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-2.482,-3.643,1.161,,,H,A,1.59,-0.88,4.659,,71.59,HHH,-1.63867,0.100394,0.00745147,0.0333997 kka2_1:8_M116S,kka2_1:8_116,Kka2,kka2_1:8,P00552,0.0333997,NO,116,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-2.482,-3.643,1.161,,,H,A,1.59,-0.88,4.659,,71.59,HHH,-1.63867,0.100394,0.00745147,0.0333997 beta-lactamase_2500_T69D,beta-lactamase_2500_69,TEM-1,beta-lactamase_2500,P62593,0.0335944,NO,69,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-0.973,-3.534,2.561,,,G,A,0.22,-1.24,2.05,,93.01,PPH,-1.01833,0.361275,0.00127498,0.0335944 kka2_1:2_L241T,kka2_1:2_241,Kka2,kka2_1:2,P00552,0.0336348,NO,241,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.158,-3.592,2.434,,0.08,H,A,0.55,-0.82,1.598,,63.26,HHH,-1.58533,0.295029,0.0117299,0.0336348 beta-lactamase_2500_I140D,beta-lactamase_2500_140,TEM-1,beta-lactamase_2500,P62593,0.0336509,NO,140,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.733,-4.079,2.346,,0.128,H,A,0.48,0.41,1.628,,73.08,PHO,-1.48733,0.361275,0.00597777,0.0336509 beta-lactamase_156_A133Q,beta-lactamase_156_133,TEM-1,beta-lactamase_156,P62593,0.0337074,NO,133,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.186,-4.056,2.87,,,H,A,0.46,-0.86,0.805,,67.83,HHP,-0.988333,0.111618,0.00468022,0.0337074 beta-lactamase_39_P181R,beta-lactamase_39_181,TEM-1,beta-lactamase_39,P62593,0.0337451,NO,181,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.813,-3.93,3.117,,,H,A,0.52,-1.14,1.946,,61.54,HOH,-1.795,0.0495842,0.000703122,0.0337451 beta-lactamase_625_L79K,beta-lactamase_625_79,TEM-1,beta-lactamase_625,P62593,0.0337694,NO,79,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.842,-3.679,2.837,,0.007,H,A,0.55,-0.16,0.935,,50.35,HHP,-1.44333,0.213352,0.000947397,0.0337694 kka2_1:4_L232E,kka2_1:4_232,Kka2,kka2_1:4,P00552,0.0338426,NO,232,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.514,-3.993,2.479,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.168804,0.00800103,0.0338426 beta-lactamase_156_T179W,beta-lactamase_156_179,TEM-1,beta-lactamase_156,P62593,0.033883,NO,179,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.085,-5.211,4.126,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.111618,0.00226045,0.033883 kka2_1:2_V198N,kka2_1:2_198,Kka2,kka2_1:2,P00552,0.0338957,NO,198,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.719,-3.977,2.258,,0.05,E,B,1.48,-0.95,1.074,,56.06,HHA,-1.88667,0.295029,0.00835002,0.0338957 beta-lactamase_2500_D177V,beta-lactamase_2500_177,TEM-1,beta-lactamase_2500,P62593,0.0339339,NO,177,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.967,-3.739,2.772,,0.006,T,L,0.75,-1.02,4.131,,64.69,BAP,-0.873667,0.361275,0.000864022,0.0339339 kka2_1:2_M197N,kka2_1:2_197,Kka2,kka2_1:2,P00552,0.0341622,NO,197,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.707,-4.155,2.448,,0.121,E,B,0.55,-1.19,2.097,,65.53,HHH,-1.847,0.295029,0.00921295,0.0341622 beta-lactamase_39_K71M,beta-lactamase_39_71,TEM-1,beta-lactamase_39,P62593,0.0343597,NO,71,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-0.8,-4.48,3.68,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.0495842,0.00103192,0.0343597 kka2_1:8_A215Y,kka2_1:8_215,Kka2,kka2_1:8,P00552,0.0346456,NO,215,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.968,-4.276,3.308,,0.039,E,B,1.04,-0.59,2.77,,50.38,HHA,-1.00467,0.100394,0.00529129,0.0346456 kka2_1:8_A215Y,kka2_1:8_215,Kka2,kka2_1:8,P00552,0.0346456,NO,215,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.968,-4.276,3.308,,0.039,E,B,1.04,-0.59,2.77,,50.38,HHA,-1.00467,0.100394,0.00529129,0.0346456 beta-lactamase_L146K,beta-lactamase_146,TEM-1,beta-lactamase,P62593,0.0347274,NO,146,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.462,-3.867,2.405,5.62483,0.007,H,A,1.3,-0.56,1.953,,64.69,AHP,-1.656,0.221079,0.00474542,0.0347274 kka2_1:2_G233Q,kka2_1:2_233,Kka2,kka2_1:2,P00552,0.0347586,NO,233,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.748,-4.098,3.35,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.295029,0.00232366,0.0347586 Pab1_I152D,Pab1_152,Pab1,Pab1,P04147,0.0347615,NO,152,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.345,-3.811,2.466,,0.165,E,B,1.23,-0.71,1.288,,71.4,AHH,-1.59433,0.175299,0.000740963,0.0347615 beta-lactamase_156_E164I,beta-lactamase_156_164,TEM-1,beta-lactamase_156,P62593,0.0347869,NO,164,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-0.948,-4.08,3.132,,0.011,T,B,1.04,-0.4,3.445,,64.69,HAO,-1.388,0.111618,0.00137286,0.0347869 kka2_1:4_G213W,kka2_1:4_213,Kka2,kka2_1:4,P00552,0.0348866,NO,213,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.596,-5.126,4.53,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.168804,0.00187654,0.0348866 beta-lactamase_625_L205D,beta-lactamase_625_205,TEM-1,beta-lactamase_625,P62593,0.0349703,NO,205,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.922,-4.118,3.196,,,H,A,0.55,-0.46,3.782,,42.31,PHH,-1.57767,0.213352,0.00255802,0.0349703 beta-lactamase_2500_M209R,beta-lactamase_2500_209,TEM-1,beta-lactamase_2500,P62593,0.0350332,NO,209,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.442,-3.939,2.497,,,H,A,0.55,-0.97,3.229,,64.69,HHA,-1.52633,0.361275,0.00625021,0.0350332 beta-lactamase_2500_K71V,beta-lactamase_2500_71,TEM-1,beta-lactamase_2500,P62593,0.0350958,NO,71,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-0.8,-3.529,2.729,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.361275,0.00103192,0.0350958 beta-lactamase_2500_M184D,beta-lactamase_2500_184,TEM-1,beta-lactamase_2500,P62593,0.0351537,NO,184,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.593,-3.936,2.343,,,H,A,0.55,-0.87,2.893,,62.94,HHH,-1.41,0.361275,0.00356019,0.0351537 kka2_1:4_L241G,kka2_1:4_241,Kka2,kka2_1:4,P00552,0.0352065,NO,241,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.158,-3.805,2.647,,0.08,H,A,0.55,-0.82,1.598,,63.26,HHH,-1.58533,0.168804,0.0117299,0.0352065 beta-lactamase_Y260G,beta-lactamase_260,TEM-1,beta-lactamase,P62593,0.0356371,NO,260,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-1.101,-3.667,2.566,5.50878,,E,B,0.73,-1.04,0.865,,60.49,HHP,-1.83433,0.221079,0.00471757,0.0356371 beta-lactamase_2500_N134W,beta-lactamase_2500_134,TEM-1,beta-lactamase_2500,P62593,0.0356565,NO,134,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-0.879,-5.545,4.666,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.361275,0.000644786,0.0356565 beta-lactamase_L136R,beta-lactamase_136,TEM-1,beta-lactamase,P62593,0.0357197,NO,136,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.232,-4.116,2.884,5.31114,,H,A,2.89,-0.34,1.539,,48.95,HHH,-1.088,0.221079,0.00442304,0.0357197 kka2_1:4_I207R,kka2_1:4_207,Kka2,kka2_1:4,P00552,0.0357888,NO,207,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.175,-4.245,3.07,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.168804,0.00611824,0.0357888 beta-lactamase_0_C121L,beta-lactamase_0_121,TEM-1,beta-lactamase_0,P62593,0.0359198,NO,121,C,L,CL,Special,Hydrophobic,5.07,9.7088,4.6388,198,121,131,10,108.5,166.7,58.2,-0.953,-3.182,2.229,,,H,A,0.46,-0.81,3.302,,63.29,HOP,-1.46767,0.0500837,0.000744322,0.0359198 beta-lactamase_G43Y,beta-lactamase_43,TEM-1,beta-lactamase,P62593,0.0363932,NO,43,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.62,-4.387,3.767,5.28886,,E,B,0.77,-0.78,,,,HOH,-1.577,0.221079,0.00120151,0.0363932 beta-lactamase_625_E164T,beta-lactamase_625_164,TEM-1,beta-lactamase_625,P62593,0.0365458,NO,164,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-0.948,-3.491,2.543,,0.011,T,B,1.04,-0.4,1.321,,64.69,HAO,-1.388,0.213352,0.00137286,0.0365458 kka2_1:2_C31I,kka2_1:2_31,Kka2,kka2_1:2,P00552,0.0366583,NO,31,C,I,CI,Special,Hydrophobic,5.07,6.02,0.95,198,121,131,10,108.5,166.7,58.2,-2.246,-3.907,1.661,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.295029,0.00681582,0.0366583 beta-lactamase_39_L136K,beta-lactamase_39_136,TEM-1,beta-lactamase_39,P62593,0.0366774,NO,136,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.232,-3.824,2.592,,,H,A,0.55,-0.34,0.336,,48.95,HHH,-1.088,0.0495842,0.00442304,0.0366774 beta-lactamase_625_V42Q,beta-lactamase_625_42,TEM-1,beta-lactamase_625,P62593,0.0368184,NO,42,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.564,-4.229,2.665,,0.017,E,B,0.44,-0.51,2.576,,63.99,BHO,-1.042,0.213352,0.00404515,0.0368184 beta-lactamase_2500_D177R,beta-lactamase_2500_177,TEM-1,beta-lactamase_2500,P62593,0.0368742,NO,177,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.967,-3.931,2.964,,0.006,T,L,0.75,-1.02,4.131,,64.69,BAP,-0.873667,0.361275,0.000864022,0.0368742 kka2_1:1_G74W,kka2_1:1_74,Kka2,kka2_1:1,P00552,0.0369702,NO,74,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.18,-5.433,4.253,,0.621,T,l,0.75,0.2,15.356,15.356,64.39,POH,-1.91667,0.520039,0.00587035,0.0369702 beta-lactamase_156_D155W,beta-lactamase_156_155,TEM-1,beta-lactamase_156,P62593,0.0373961,NO,155,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.889,-5.571,4.682,,0.049,,B,0.75,-0.9,0.315,,64.69,OAB,-1.62267,0.111618,0.00135315,0.0373961 kka2_1:8_E262I,kka2_1:8_262,Kka2,kka2_1:8,P00552,0.0374318,NO,262,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-0.829,-4.062,3.233,,0.059,G,A,1.52,-0.18,0.837,,42.42,AAH,-0.816,0.100394,0.0191586,0.0374318 kka2_1:8_E262I,kka2_1:8_262,Kka2,kka2_1:8,P00552,0.0374318,NO,262,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-0.829,-4.062,3.233,,0.059,G,A,1.52,-0.18,0.837,,42.42,AAH,-0.816,0.100394,0.0191586,0.0374318 kka2_1:2_R44I,kka2_1:2_44,Kka2,kka2_1:2,P00552,0.0378634,NO,44,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.062,-4.031,1.969,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.295029,0.00745043,0.0378634 kka2_1:1_A78N,kka2_1:1_78,Kka2,kka2_1:1,P00552,0.0378856,NO,78,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.744,-3.971,2.227,,0.078,.,B,0.46,-0.53,0.206,,56.06,OHH,-1.863,0.520039,0.00457299,0.0378856 beta-lactamase_2500_G76R,beta-lactamase_2500_76,TEM-1,beta-lactamase_2500,P62593,0.038015,NO,76,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.189,-3.905,2.716,,,H,A,0.29,-0.67,1.012,,67.83,OOH,-1.22267,0.361275,0.00476637,0.038015 beta-lactamase_V257K,beta-lactamase_257,TEM-1,beta-lactamase,P62593,0.0382638,NO,257,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.533,-3.788,2.255,5.31999,,E,B,0.96,-0.7,1.463,,58.74,HHH,-1.70967,0.221079,0.00756629,0.0382638 beta-lactamase_2500_A246H,beta-lactamase_2500_246,TEM-1,beta-lactamase_2500,P62593,0.0382844,NO,246,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.121,-4.964,2.843,,0.01,E,B,0.46,-1.01,0.753,,73.78,HHH,-1.55633,0.361275,0.00569458,0.0382844 beta-lactamase_156_L205D,beta-lactamase_156_205,TEM-1,beta-lactamase_156,P62593,0.0385858,NO,205,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.922,-4.118,3.196,,,H,A,0.55,-0.46,0.678,,42.31,PHH,-1.57767,0.111618,0.00255802,0.0385858 kka2_1:1_A176P,kka2_1:1_176,Kka2,kka2_1:1,P00552,0.03859,NO,176,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.621,-3.934,2.313,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.520039,0.0083587,0.03859 PSD95pdz3_A375R,PSD95pdz3_375,PSD95pdz3,PSD95pdz3,P31016,0.0386363,NO,375,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.307,-3.39,2.083,5.05512,,,,,13.888,,,,PHH,-1.43767,0.0758425,0.000356809,0.0386363 kka2_1:8_G151I,kka2_1:8_151,Kka2,kka2_1:8,P00552,0.0389695,NO,151,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.873,-4.249,3.376,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.100394,0.00339918,0.0389695 kka2_1:8_G151I,kka2_1:8_151,Kka2,kka2_1:8,P00552,0.0389695,NO,151,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.873,-4.249,3.376,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.100394,0.00339918,0.0389695 beta-lactamase_2500_I125R,beta-lactamase_2500_125,TEM-1,beta-lactamase_2500,P62593,0.0390058,NO,125,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.441,-4.126,2.685,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.361275,0.00383964,0.0390058 beta-lactamase_156_S233K,beta-lactamase_156_233,TEM-1,beta-lactamase_156,P62593,0.0390618,NO,233,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.886,-3.496,1.61,,0.016,E,B,0.27,-1.01,4.111,,77.62,BPO,-1.17267,0.111618,0.00311415,0.0390618 beta-lactamase_156_A132Y,beta-lactamase_156_132,TEM-1,beta-lactamase_156,P62593,0.0391144,NO,132,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.9,-4.186,3.286,,,H,A,0.46,-0.93,10.621,,64.69,PHH,-1.138,0.111618,0.000962524,0.0391144 beta-lactamase_625_S128E,beta-lactamase_625_128,TEM-1,beta-lactamase_625,P62593,0.0393521,NO,128,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-0.84,-3.215,2.375,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.213352,0.00071483,0.0393521 beta-lactamase_2500_S128H,beta-lactamase_2500_128,TEM-1,beta-lactamase_2500,P62593,0.0393879,NO,128,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-0.84,-4.455,3.615,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.361275,0.00071483,0.0393879 beta-lactamase_39_K232M,beta-lactamase_39_232,TEM-1,beta-lactamase_39,P62593,0.039405,NO,232,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.012,-4.522,3.51,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.0495842,0.00313441,0.039405 beta-lactamase_2500_D177T,beta-lactamase_2500_177,TEM-1,beta-lactamase_2500,P62593,0.0394197,NO,177,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.967,-3.465,2.498,,0.006,T,L,0.75,-1.02,4.131,,64.69,BAP,-0.873667,0.361275,0.000864022,0.0394197 beta-lactamase_R59P,beta-lactamase_59,TEM-1,beta-lactamase,P62593,0.0395826,NO,59,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.345,-3.961,2.616,5.49837,0.329,S,L,0.68,-0.09,1.806,,73.08,HBO,-2.24267,0.221079,0.00318082,0.0395826 beta-lactamase_156_S68Y,beta-lactamase_156_68,TEM-1,beta-lactamase_156,P62593,0.0395928,NO,68,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-0.913,-4.188,3.275,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.111618,0.000800065,0.0395928 PSD95pdz3_I338E,PSD95pdz3_338,PSD95pdz3,PSD95pdz3,P31016,0.0396956,NO,338,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.63,-3.572,1.942,5.45113,,,,,13.0087,,,,HHP,-1.55767,0.0758425,0.000862587,0.0396956 beta-lactamase_625_D177Y,beta-lactamase_625_177,TEM-1,beta-lactamase_625,P62593,0.0399117,NO,177,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.967,-4.413,3.446,,0.006,T,L,0.75,-1.02,1.333,,64.69,BAP,-0.873667,0.213352,0.000864022,0.0399117 beta-lactamase_39_W227P,beta-lactamase_39_227,TEM-1,beta-lactamase_39,P62593,0.0400145,NO,227,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-0.982,-4.323,3.341,,0.272,,B,0.47,-0.29,1.37,,74.48,OHH,-1.595,0.0495842,0.00226019,0.0400145 kka2_1:2_V113P,kka2_1:2_113,Kka2,kka2_1:2,P00552,0.0401816,NO,113,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.233,-4.102,2.869,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.295029,0.00650191,0.0401816 beta-lactamase_2500_L74Q,beta-lactamase_2500_74,TEM-1,beta-lactamase_2500,P62593,0.040236,NO,74,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.296,-4.107,2.811,,,H,A,0.55,-0.91,0.746,,50,HHO,-1.34933,0.361275,0.00493255,0.040236 kka2_1:4_V75G,kka2_1:4_75,Kka2,kka2_1:4,P00552,0.0402423,NO,75,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-2.06,-3.863,1.803,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.168804,0.00693733,0.0402423 kka2_1:1_R173Y,kka2_1:1_173,Kka2,kka2_1:1,P00552,0.0402771,NO,173,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.407,-3.028,0.621,,0.308,H,A,0.16,-0.13,14.756,14.756,65.53,HBH,-1.70533,0.520039,0.00784999,0.0402771 beta-lactamase_2500_R59D,beta-lactamase_2500_59,TEM-1,beta-lactamase_2500,P62593,0.0403235,NO,59,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.345,-3.634,2.289,,0.329,S,L,1.2,-0.09,3.719,,73.08,HBO,-2.24267,0.361275,0.00318082,0.0403235 beta-lactamase_156_M209N,beta-lactamase_156_209,TEM-1,beta-lactamase_156,P62593,0.0404199,NO,209,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.442,-4.092,2.65,,,H,A,0.55,-0.97,1.066,,64.69,HHA,-1.52633,0.111618,0.00625021,0.0404199 beta-lactamase_C121H,beta-lactamase_121,TEM-1,beta-lactamase,P62593,0.0408356,NO,121,C,H,CH,Special,PositiveCharge,5.07,7.59,2.52,174,121,155,34,108.5,153.2,44.7,-0.953,-4.827,3.874,5.12205,,H,A,2.8,-0.81,7.644,,63.29,HOP,-1.46767,0.221079,0.000744322,0.0408356 beta-lactamase_L120K,beta-lactamase_120,TEM-1,beta-lactamase,P62593,0.0408356,NO,120,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.044,-3.668,2.624,5.11974,,H,A,1.3,-1.13,1.988,,64.69,AHO,-1.13633,0.221079,0.00143563,0.0408356 beta-lactamase_L74D,beta-lactamase_74,TEM-1,beta-lactamase,P62593,0.0408356,NO,74,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.296,-4.023,2.727,5.50288,,H,A,1.75,-0.91,1.581,,50,HHO,-1.34933,0.221079,0.00493255,0.0408356 beta-lactamase_W208P,beta-lactamase_208,TEM-1,beta-lactamase,P62593,0.0408356,NO,208,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-0.818,-4.33,3.512,5.26277,0.067,H,A,0.99,-0.65,,,,AHH,-1.44133,0.221079,0.00126609,0.0408356 beta-lactamase_39_S128E,beta-lactamase_39_128,TEM-1,beta-lactamase_39,P62593,0.040991,NO,128,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-0.84,-3.215,2.375,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.0495842,0.00071483,0.040991 PSD95pdz3_I359H,PSD95pdz3_359,PSD95pdz3,PSD95pdz3,P31016,0.0413159,NO,359,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.63,-4.587,2.957,5.35151,,,,,14.8012,,,,PHH,-1.58667,0.0758425,0.000580694,0.0413159 kka2_1:4_V49P,kka2_1:4_49,Kka2,kka2_1:4,P00552,0.041337,NO,49,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.614,-4.128,2.514,,,E,B,0.44,-0.77,1.233,,64.39,HHB,-1.3,0.168804,0.00615685,0.041337 PSD95pdz3_I327A,PSD95pdz3_327,PSD95pdz3,PSD95pdz3,P31016,0.0414405,NO,327,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.63,-2.759,1.129,5.7413,,,,,14.0388,,,,PHH,-1.50167,0.0758425,0.000998774,0.0414405 kka2_1:1_V186I,kka2_1:1_186,Kka2,kka2_1:1,P00552,0.0416481,NO,186,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.011,-2.092,1.081,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.520039,0.00409703,0.0416481 beta-lactamase_625_K71V,beta-lactamase_625_71,TEM-1,beta-lactamase_625,P62593,0.0416688,NO,71,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-0.8,-3.529,2.729,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.213352,0.00103192,0.0416688 kka2_1:8_A144N,kka2_1:8_144,Kka2,kka2_1:8,P00552,0.0417194,NO,144,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.859,-4.009,3.15,,,H,A,1.04,0.21,1.118,,52.65,BHB,-1.72933,0.100394,0.00231095,0.0417194 kka2_1:8_A144N,kka2_1:8_144,Kka2,kka2_1:8,P00552,0.0417194,NO,144,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.859,-4.009,3.15,,,H,A,1.04,0.21,1.118,,52.65,BHB,-1.72933,0.100394,0.00231095,0.0417194 beta-lactamase_156_E164V,beta-lactamase_156_164,TEM-1,beta-lactamase_156,P62593,0.0417385,NO,164,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-0.948,-3.599,2.651,,0.011,T,B,1.04,-0.4,3.445,,64.69,HAO,-1.388,0.111618,0.00137286,0.0417385 beta-lactamase_625_S68K,beta-lactamase_625_68,TEM-1,beta-lactamase_625,P62593,0.0418175,NO,68,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-0.913,-3.258,2.345,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.213352,0.000800065,0.0418175 beta-lactamase_625_G243M,beta-lactamase_625_243,TEM-1,beta-lactamase_625,P62593,0.0419242,NO,243,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.213352,0.00464034,0.0419242 beta-lactamase_2500_G76P,beta-lactamase_2500_76,TEM-1,beta-lactamase_2500,P62593,0.0420551,NO,76,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.189,-3.852,2.663,,,H,A,0.29,-0.67,1.012,,67.83,OOH,-1.22267,0.361275,0.00476637,0.0420551 kka2_1:8_F171N,kka2_1:8_171,Kka2,kka2_1:8,P00552,0.0423274,NO,171,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.326,-4.165,2.839,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.100394,0.00821426,0.0423274 kka2_1:8_F171N,kka2_1:8_171,Kka2,kka2_1:8,P00552,0.0423274,NO,171,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.326,-4.165,2.839,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.100394,0.00821426,0.0423274 beta-lactamase_625_G234F,beta-lactamase_625_234,TEM-1,beta-lactamase_625,P62593,0.0424783,NO,234,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.62,-4.292,3.672,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.213352,0.000889577,0.0424783 beta-lactamase_T158P,beta-lactamase_158,TEM-1,beta-lactamase,P62593,0.0424828,NO,158,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.116,-2.676,1.56,5.32011,0.036,,B,0.98,-0.85,2.755,,69.58,HPB,-1.269,0.221079,0.00341825,0.0424828 beta-lactamase_2500_D155C,beta-lactamase_2500_155,TEM-1,beta-lactamase_2500,P62593,0.0427506,NO,155,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.889,-5.157,4.268,,0.049,,B,0.75,-0.9,2.386,,64.69,OAB,-1.62267,0.361275,0.00135315,0.0427506 beta-lactamase_39_S128D,beta-lactamase_39_128,TEM-1,beta-lactamase_39,P62593,0.0428615,NO,128,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-0.84,-3.244,2.404,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.0495842,0.00071483,0.0428615 kka2_1:2_G74W,kka2_1:2_74,Kka2,kka2_1:2,P00552,0.0429136,NO,74,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.18,-5.433,4.253,,0.621,T,l,0.75,0.2,1.446,,64.39,POH,-1.91667,0.295029,0.00587035,0.0429136 beta-lactamase_2500_E164H,beta-lactamase_2500_164,TEM-1,beta-lactamase_2500,P62593,0.0429457,NO,164,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-0.948,-4.339,3.391,,0.011,T,B,1.04,-0.4,0.352,,64.69,HAO,-1.388,0.361275,0.00137286,0.0429457 beta-lactamase_2500_C75N,beta-lactamase_2500_75,TEM-1,beta-lactamase_2500,P62593,0.0430089,NO,75,C,N,CN,Special,Polar,5.07,5.47157,0.401575,139,121,132,11,108.5,114.1,5.6,-1.245,-3.973,2.728,,,H,A,0.46,-0.87,0.844,,50,HOO,-1.24333,0.361275,0.0034616,0.0430089 kka2_1:1_G74F,kka2_1:1_74,Kka2,kka2_1:1,P00552,0.0431729,NO,74,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.18,-4.449,3.269,,0.621,T,l,0.75,0.2,15.356,15.356,64.39,POH,-1.91667,0.520039,0.00587035,0.0431729 beta-lactamase_A133E,beta-lactamase_133,TEM-1,beta-lactamase,P62593,0.0434076,NO,133,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.186,-3.597,2.411,4.86423,,H,A,0.55,-0.86,2.649,,67.83,HHP,-0.988333,0.221079,0.00468022,0.0434076 kka2_1:2_P194W,kka2_1:2_194,Kka2,kka2_1:2,P00552,0.0435319,NO,194,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.846,-5.598,4.752,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.295029,0.00314194,0.0435319 beta-lactamase_L150K,beta-lactamase_150,TEM-1,beta-lactamase,P62593,0.0435505,NO,150,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.326,-3.711,2.385,5.15566,,H,A,1.75,-0.2,1.615,,62.94,HHB,-1.86167,0.221079,0.00463171,0.0435505 beta-lactamase_625_L79R,beta-lactamase_625_79,TEM-1,beta-lactamase_625,P62593,0.0437504,NO,79,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.842,-3.93,3.088,,0.007,H,A,0.55,-0.16,0.935,,50.35,HHP,-1.44333,0.213352,0.000947397,0.0437504 kka2_1:4_L212W,kka2_1:4_212,Kka2,kka2_1:4,P00552,0.0438226,NO,212,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.904,-5.226,4.322,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.168804,0.0031426,0.0438226 beta-lactamase_2500_W227S,beta-lactamase_2500_227,TEM-1,beta-lactamase_2500,P62593,0.0440296,NO,227,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-0.982,-3.768,2.786,,0.272,,B,0.47,-0.29,1.37,,74.48,OHH,-1.595,0.361275,0.00226019,0.0440296 beta-lactamase_156_V31E,beta-lactamase_156_31,TEM-1,beta-lactamase_156,P62593,0.0440943,NO,31,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.822,-3.908,2.086,,,H,A,0.44,-0.46,4.126,,73.78,BHB,-2.03767,0.111618,0.00478065,0.0440943 beta-lactamase_T187P,beta-lactamase_187,TEM-1,beta-lactamase,P62593,0.0443261,NO,187,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.401,-3.906,2.505,5.11453,0.007,H,A,0.3,-1.19,1.751,,67.48,PPH,-1.69633,0.221079,0.00491782,0.0443261 kka2_1:2_M116W,kka2_1:2_116,Kka2,kka2_1:2,P00552,0.0443799,NO,116,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-2.482,-5.227,2.745,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.295029,0.00745147,0.0443799 beta-lactamase_625_T179W,beta-lactamase_625_179,TEM-1,beta-lactamase_625,P62593,0.0444102,NO,179,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.085,-5.211,4.126,,,E,B,0.22,-1.38,0.367,,73.08,PPH,-1.557,0.213352,0.00226045,0.0444102 kka2_1:4_H188I,kka2_1:4_188,Kka2,kka2_1:4,P00552,0.0444819,NO,188,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-0.913,-4.062,3.149,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.168804,0.00273139,0.0444819 beta-lactamase_2500_W288G,beta-lactamase_2500_288,TEM-1,beta-lactamase_2500,P62593,0.0445314,NO,288,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,,,,,,,,,,,,,BHO,,0.361275,,0.0445314 beta-lactamase_M1G,beta-lactamase_1,TEM-1,beta-lactamase,P62593,0.0445947,NO,1,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.998,-3.265,1.267,,,,,,,,,,OHP,-1.97,0.221079,0.00162771,0.0445947 beta-lactamase_2500_K71H,beta-lactamase_2500_71,TEM-1,beta-lactamase_2500,P62593,0.044704,NO,71,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-0.8,-4.455,3.655,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.361275,0.00103192,0.044704 beta-lactamase_L146P,beta-lactamase_146,TEM-1,beta-lactamase,P62593,0.044714,NO,146,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.462,-4.216,2.754,5.62483,0.007,H,A,1.3,-0.56,1.953,,64.69,AHP,-1.656,0.221079,0.00474542,0.044714 beta-lactamase_W227D,beta-lactamase_227,TEM-1,beta-lactamase,P62593,0.0449079,NO,227,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-0.982,-4.076,3.094,4.86393,0.272,,B,0.99,-0.29,1.37,,74.48,OHH,-1.595,0.221079,0.00226019,0.0449079 beta-lactamase_2500_D177H,beta-lactamase_2500_177,TEM-1,beta-lactamase_2500,P62593,0.0449706,NO,177,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.967,-4.511,3.544,,0.006,T,L,0.75,-1.02,4.131,,64.69,BAP,-0.873667,0.361275,0.000864022,0.0449706 beta-lactamase_2500_F64K,beta-lactamase_2500_64,TEM-1,beta-lactamase_2500,P62593,0.0449759,NO,64,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-0.841,-3.907,3.066,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.361275,0.000947691,0.0449759 beta-lactamase_156_L136Y,beta-lactamase_156_136,TEM-1,beta-lactamase_156,P62593,0.0451033,NO,136,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.232,-4.051,2.819,,,H,A,0.55,-0.34,1.04,,48.95,HHH,-1.088,0.111618,0.00442304,0.0451033 beta-lactamase_39_C75K,beta-lactamase_39_75,TEM-1,beta-lactamase_39,P62593,0.0452369,NO,75,C,K,CK,Special,PositiveCharge,5.07,9.74,4.67,202,121,146,25,108.5,168.6,60.1,-1.245,-3.786,2.541,,,H,A,0.46,-0.87,2.369,,50,HOO,-1.24333,0.0495842,0.0034616,0.0452369 kka2_1:2_F256G,kka2_1:2_256,Kka2,kka2_1:2,P00552,0.0453179,NO,256,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.49,-3.713,2.223,,,H,A,0.58,-0.78,1.653,,53.03,HHH,-1.423,0.295029,0.0132841,0.0453179 kka2_1:8_L174N,kka2_1:8_174,Kka2,kka2_1:8,P00552,0.0453504,NO,174,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.952,-4.185,3.233,,,H,A,1.59,-0.31,1.204,,51.89,BHB,-2.08533,0.100394,0.00438501,0.0453504 kka2_1:8_L174N,kka2_1:8_174,Kka2,kka2_1:8,P00552,0.0453504,NO,174,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.952,-4.185,3.233,,,H,A,1.59,-0.31,1.204,,51.89,BHB,-2.08533,0.100394,0.00438501,0.0453504 beta-lactamase_2500_I245P,beta-lactamase_2500_245,TEM-1,beta-lactamase_2500,P62593,0.0454489,NO,245,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.361275,0.00391032,0.0454489 beta-lactamase_156_G43K,beta-lactamase_156_43,TEM-1,beta-lactamase_156,P62593,0.0455488,NO,43,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.62,-3.682,3.062,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.111618,0.00120151,0.0455488 beta-lactamase_2500_N130P,beta-lactamase_2500_130,TEM-1,beta-lactamase_2500,P62593,0.0455607,NO,130,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-0.798,-3.88,3.082,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.361275,0.000683376,0.0455607 beta-lactamase_39_G234R,beta-lactamase_39_234,TEM-1,beta-lactamase_39,P62593,0.0457166,NO,234,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.62,-3.933,3.313,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.0495842,0.000889577,0.0457166 beta-lactamase_2500_G243E,beta-lactamase_2500_243,TEM-1,beta-lactamase_2500,P62593,0.0459568,NO,243,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.361275,0.00464034,0.0459568 beta-lactamase_M66K,beta-lactamase_66,TEM-1,beta-lactamase,P62593,0.0459795,NO,66,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.362,-3.657,2.295,5.29561,0.013,,A,1.3,-0.7,1.319,,73.08,OHH,-1.49567,0.221079,0.00412876,0.0459795 beta-lactamase_625_L248Q,beta-lactamase_625_248,TEM-1,beta-lactamase_625,P62593,0.0461552,NO,248,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.213352,0.00428493,0.0461552 beta-lactamase_L282P,beta-lactamase_282,TEM-1,beta-lactamase,P62593,0.0462654,NO,282,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.586,-2.919,1.333,5.16743,0.007,H,A,1.07,0.34,31.31,31.31,63.99,PHH,-1.82367,0.221079,0.0449821,0.0462654 beta-lactamase_625_W227E,beta-lactamase_625_227,TEM-1,beta-lactamase_625,P62593,0.0462981,NO,227,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-0.982,-3.914,2.932,,0.272,,B,0.47,-0.29,2.533,,74.48,OHH,-1.595,0.213352,0.00226019,0.0462981 kka2_1:1_T73D,kka2_1:1_73,Kka2,kka2_1:1,P00552,0.0464207,NO,73,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.51,-3.789,1.279,,0.309,H,A,0.22,0.35,4.126,,56.06,PPO,-2.02333,0.520039,0.00628605,0.0464207 kka2_1:2_I115H,kka2_1:2_115,Kka2,kka2_1:2,P00552,0.0464652,NO,115,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.606,-5.024,3.418,,0.105,H,A,0.48,-1.18,0.878,,65.53,PHH,-2.205,0.295029,0.00836567,0.0464652 beta-lactamase_2500_E164A,beta-lactamase_2500_164,TEM-1,beta-lactamase_2500,P62593,0.0464889,NO,164,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-0.948,-3.102,2.154,,0.011,T,B,1.04,-0.4,0.352,,64.69,HAO,-1.388,0.361275,0.00137286,0.0464889 kka2_1:4_Y218P,kka2_1:4_218,Kka2,kka2_1:4,P00552,0.0465805,NO,218,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-1.438,-4.207,2.769,,0.122,H,A,0.21,-0.69,1.022,,56.06,BHP,-1.17533,0.168804,0.0126098,0.0465805 beta-lactamase_2500_Y262W,beta-lactamase_2500_262,TEM-1,beta-lactamase_2500,P62593,0.0466053,NO,262,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.361275,0.00853516,0.0466053 kka2_1:4_A117W,kka2_1:4_117,Kka2,kka2_1:4,P00552,0.0470731,NO,117,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.828,-5.385,4.557,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.168804,0.00282984,0.0470731 kka2_1:2_F264M,kka2_1:2_264,Kka2,kka2_1:2,P00552,0.0472869,NO,264,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.02,-4.352,3.332,,0.296,.,?,0.58,0.02,2.303,,71.59,HHNA,-0.9655,0.295029,,0.0472869 kka2_1:1_T187K,kka2_1:1_187,Kka2,kka2_1:1,P00552,0.0473686,NO,187,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.273,-3.655,2.382,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.520039,0.00693073,0.0473686 beta-lactamase_625_A246Q,beta-lactamase_625_246,TEM-1,beta-lactamase_625,P62593,0.0476215,NO,246,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.121,-4.263,2.142,,0.01,E,B,0.46,-1.01,1.201,,73.78,HHH,-1.55633,0.213352,0.00569458,0.0476215 kka2_1:4_F206G,kka2_1:4_206,Kka2,kka2_1:4,P00552,0.0477301,NO,206,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.349,-3.746,2.397,,0.006,E,B,0.58,-1.21,1.342,,63.64,OHH,-1.04,0.168804,0.00936868,0.0477301 beta-lactamase_625_V31Q,beta-lactamase_625_31,TEM-1,beta-lactamase_625,P62593,0.0477405,NO,31,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.822,-4.296,2.474,,,H,A,0.44,-0.46,2.576,,73.78,BHB,-2.03767,0.213352,0.00478065,0.0477405 kka2_1:8_V186F,kka2_1:8_186,Kka2,kka2_1:8,P00552,0.047749,NO,186,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.011,-2.866,1.855,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.100394,0.00409703,0.047749 kka2_1:8_V186F,kka2_1:8_186,Kka2,kka2_1:8,P00552,0.047749,NO,186,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.011,-2.866,1.855,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.100394,0.00409703,0.047749 beta-lactamase_156_G243K,beta-lactamase_156_243,TEM-1,beta-lactamase_156,P62593,0.0477631,NO,243,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.532,,,,,E,B,0.77,-1.24,2.866,,50,BOH,-1.46867,0.111618,0.00464034,0.0477631 beta-lactamase_156_L192P,beta-lactamase_156_192,TEM-1,beta-lactamase_156,P62593,0.0477818,NO,192,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.254,-4.129,2.875,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.111618,0.00558728,0.0477818 beta-lactamase_2500_L205R,beta-lactamase_2500_205,TEM-1,beta-lactamase_2500,P62593,0.0481318,NO,205,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.922,-3.987,3.065,,,H,A,0.55,-0.46,0.831,,42.31,PHH,-1.57767,0.361275,0.00255802,0.0481318 beta-lactamase_39_A132I,beta-lactamase_39_132,TEM-1,beta-lactamase_39,P62593,0.0481935,NO,132,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.9,-3.489,2.589,,,H,A,0.46,-0.93,8.408,,64.69,PHH,-1.138,0.0495842,0.000962524,0.0481935 Pab1_F149D,Pab1_149,Pab1,Pab1,P04147,0.0483291,NO,149,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.149,-3.736,2.587,,0.183,T,A,1.33,1.09,,,,HHO,-1.27767,0.175299,0.000325688,0.0483291 beta-lactamase_625_C121F,beta-lactamase_625_121,TEM-1,beta-lactamase_625,P62593,0.0486224,NO,121,C,F,CF,Special,Hydrophobic,5.07,3.32051,-1.74949,205,121,165,44,108.5,189.9,81.4,-0.953,-4.116,3.163,,,H,A,0.46,-0.81,1.143,,63.29,HOP,-1.46767,0.213352,0.000744322,0.0486224 beta-lactamase_156_M66K,beta-lactamase_156_66,TEM-1,beta-lactamase_156,P62593,0.0486803,NO,66,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.362,-3.657,2.295,,0.013,,A,0.55,-0.7,1.94,,73.08,OHH,-1.49567,0.111618,0.00412876,0.0486803 beta-lactamase_39_I258D,beta-lactamase_39_258,TEM-1,beta-lactamase_39,P62593,0.0487952,NO,258,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.0495842,0.007931,0.0487952 beta-lactamase_2500_W227L,beta-lactamase_2500_227,TEM-1,beta-lactamase_2500,P62593,0.0487986,NO,227,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-0.982,-3.387,2.405,,0.272,,B,0.47,-0.29,1.37,,74.48,OHH,-1.595,0.361275,0.00226019,0.0487986 beta-lactamase_2500_E164R,beta-lactamase_2500_164,TEM-1,beta-lactamase_2500,P62593,0.0489187,NO,164,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-0.948,-3.511,2.563,,0.011,T,B,1.04,-0.4,0.352,,64.69,HAO,-1.388,0.361275,0.00137286,0.0489187 beta-lactamase_2500_T178W,beta-lactamase_2500_178,TEM-1,beta-lactamase_2500,P62593,0.0489286,NO,178,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-0.791,-5.097,4.306,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.361275,0.000684366,0.0489286 beta-lactamase_E210P,beta-lactamase_210,TEM-1,beta-lactamase,P62593,0.04898,NO,210,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.319,-4.023,1.704,5.7398,0.476,H,A,0.52,0.75,1.555,,77.62,HAH,-1.88567,0.221079,0.00663582,0.04898 beta-lactamase_I125Y,beta-lactamase_125,TEM-1,beta-lactamase,P62593,0.04898,NO,125,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.441,-4.111,2.67,5.23481,,H,A,2.82,-0.7,2.301,,63.29,HHP,-1.248,0.221079,0.00383964,0.04898 kka2_1:2_I196K,kka2_1:2_196,Kka2,kka2_1:2,P00552,0.0490251,NO,196,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-2.115,-3.976,1.861,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.295029,0.0107273,0.0490251 beta-lactamase_625_Y44E,beta-lactamase_625_44,TEM-1,beta-lactamase_625,P62593,0.0491846,NO,44,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-2.547,-3.866,1.319,,,E,B,0.21,-0.45,2.371,,73.78,OHH,-1.86267,0.213352,0.00426364,0.0491846 kka2_1:2_A34M,kka2_1:2_34,Kka2,kka2_1:2,P00552,0.049336,NO,34,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.928,-4.54,3.612,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.295029,0.00343484,0.049336 beta-lactamase_K232I,beta-lactamase_232,TEM-1,beta-lactamase,P62593,0.0495618,NO,232,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.012,-4.053,3.041,5.18286,,E,B,2.92,-1.1,1.174,,65.03,ABP,-1.238,0.221079,0.00313441,0.0495618 kka2_1:4_D261F,kka2_1:4_261,Kka2,kka2_1:4,P00552,0.0496546,NO,261,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.708,-4.32,3.612,,0.146,G,A,0.75,-0.33,,,,HAA,-0.759333,0.168804,0.0224846,0.0496546 beta-lactamase_T69D,beta-lactamase_69,TEM-1,beta-lactamase,P62593,0.0497205,NO,69,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-0.973,-3.534,2.561,5.16042,,G,A,0.69,-1.24,0.505,,93.01,PPH,-1.01833,0.221079,0.00127498,0.0497205 beta-lactamase_625_L79H,beta-lactamase_625_79,TEM-1,beta-lactamase_625,P62593,0.0498175,NO,79,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.842,-4.903,4.061,,0.007,H,A,0.55,-0.16,0.935,,50.35,HHP,-1.44333,0.213352,0.000947397,0.0498175 kka2_1:8_H188I,kka2_1:8_188,Kka2,kka2_1:8,P00552,0.0501302,NO,188,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-0.913,-4.062,3.149,,0.006,,A,0.87,-1.02,1.241,,47.73,PBO,-0.927333,0.100394,0.00273139,0.0501302 kka2_1:8_H188I,kka2_1:8_188,Kka2,kka2_1:8,P00552,0.0501302,NO,188,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-0.913,-4.062,3.149,,0.006,,A,0.87,-1.02,1.241,,47.73,PBO,-0.927333,0.100394,0.00273139,0.0501302 kka2_1:4_D190K,kka2_1:4_190,Kka2,kka2_1:4,P00552,0.0501416,NO,190,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.708,-3.485,2.777,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.168804,0.00247989,0.0501416 beta-lactamase_625_K71D,beta-lactamase_625_71,TEM-1,beta-lactamase_625,P62593,0.0503161,NO,71,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-0.8,-3.469,2.669,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.213352,0.00103192,0.0503161 beta-lactamase_L191R,beta-lactamase_191,TEM-1,beta-lactamase,P62593,0.0503172,NO,191,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.087,-4.02,2.933,5.72226,,H,A,1.07,0.09,1.23,,63.29,BHH,-1.445,0.221079,0.00263549,0.0503172 kka2_1:4_A34W,kka2_1:4_34,Kka2,kka2_1:4,P00552,0.0504188,NO,34,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.928,-5.383,4.455,,0.417,.,B,0.46,2.29,0.262,,52.27,AHH,-1.747,0.168804,0.00343484,0.0504188 beta-lactamase_2500_G249L,beta-lactamase_2500_249,TEM-1,beta-lactamase_2500,P62593,0.050493,NO,249,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.312,,,,0.256,S,B,0.23,0.04,30.841,30.841,72.73,HOO,-1.81367,0.361275,0.00220169,0.050493 beta-lactamase_625_A133M,beta-lactamase_625_133,TEM-1,beta-lactamase_625,P62593,0.0505852,NO,133,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.186,-4.694,3.508,,,H,A,0.46,-0.86,0.373,,67.83,HHP,-0.988333,0.213352,0.00468022,0.0505852 beta-lactamase_2500_S128E,beta-lactamase_2500_128,TEM-1,beta-lactamase_2500,P62593,0.050591,NO,128,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-0.84,-3.215,2.375,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.361275,0.00071483,0.050591 beta-lactamase_M209K,beta-lactamase_209,TEM-1,beta-lactamase,P62593,0.0506089,NO,209,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.442,-3.673,2.231,5.44502,,H,A,1.75,-0.97,1.402,,64.69,HHA,-1.52633,0.221079,0.00625021,0.0506089 beta-lactamase_39_I258P,beta-lactamase_39_258,TEM-1,beta-lactamase_39,P62593,0.0508336,NO,258,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.0495842,0.007931,0.0508336 PSD95pdz3_V328P,PSD95pdz3_328,PSD95pdz3,PSD95pdz3,P31016,0.0508503,NO,328,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.465,-3.561,2.096,5.28275,,,,,16.8775,,,,HHO,-1.36767,0.0758425,0.000986706,0.0508503 beta-lactamase_156_L136W,beta-lactamase_156_136,TEM-1,beta-lactamase_156,P62593,0.050865,NO,136,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.232,-5.281,4.049,,,H,A,0.55,-0.34,1.04,,48.95,HHH,-1.088,0.111618,0.00442304,0.050865 beta-lactamase_2500_D177C,beta-lactamase_2500_177,TEM-1,beta-lactamase_2500,P62593,0.0509229,NO,177,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.967,-5.073,4.106,,0.006,T,L,0.75,-1.02,4.131,,64.69,BAP,-0.873667,0.361275,0.000864022,0.0509229 kka2_1:4_M197W,kka2_1:4_197,Kka2,kka2_1:4,P00552,0.0509949,NO,197,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.707,-5.268,3.561,,0.121,E,B,0.55,-1.19,0.415,,65.53,HHH,-1.847,0.168804,0.00921295,0.0509949 kka2_1:8_G189I,kka2_1:8_189,Kka2,kka2_1:8,P00552,0.0510187,NO,189,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.596,-4.264,3.668,,0.034,S,l,0.75,-0.99,,,,BOA,-0.739,0.100394,0.00253688,0.0510187 kka2_1:8_G189I,kka2_1:8_189,Kka2,kka2_1:8,P00552,0.0510187,NO,189,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.596,-4.264,3.668,,0.034,S,l,0.75,-0.99,,,,BOA,-0.739,0.100394,0.00253688,0.0510187 beta-lactamase_156_A246H,beta-lactamase_156_246,TEM-1,beta-lactamase_156,P62593,0.0510231,NO,246,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.121,-4.964,2.843,,0.01,E,B,0.46,-1.01,1.959,,73.78,HHH,-1.55633,0.111618,0.00569458,0.0510231 kka2_1:2_V36Y,kka2_1:2_36,Kka2,kka2_1:2,P00552,0.0511044,NO,36,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-0.898,-4.01,3.112,,0.292,E,B,1.48,0.21,1.064,,52.27,HHH,-1.484,0.295029,0.00245633,0.0511044 beta-lactamase_156_S68F,beta-lactamase_156_68,TEM-1,beta-lactamase_156,P62593,0.0513918,NO,68,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-0.913,-4.116,3.203,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.111618,0.000800065,0.0513918 kka2_1:4_T187F,kka2_1:4_187,Kka2,kka2_1:4,P00552,0.0514666,NO,187,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.273,-4.193,2.92,,0.007,E,B,0.22,-0.85,2.73,,52.27,HPB,-1.06567,0.168804,0.00693073,0.0514666 beta-lactamase_39_G243W,beta-lactamase_39_243,TEM-1,beta-lactamase_39,P62593,0.0514906,NO,243,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.0495842,0.00464034,0.0514906 beta-lactamase_2500_D48P,beta-lactamase_2500_48,TEM-1,beta-lactamase_2500,P62593,0.0515116,NO,48,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.101,-3.766,2.665,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.361275,0.0027273,0.0515116 kka2_1:8_S32E,kka2_1:8_32,Kka2,kka2_1:8,P00552,0.0516097,NO,32,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-0.804,-3.243,2.439,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.100394,0.00149998,0.0516097 kka2_1:8_S32E,kka2_1:8_32,Kka2,kka2_1:8,P00552,0.0516097,NO,32,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-0.804,-3.243,2.439,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.100394,0.00149998,0.0516097 kka2_1:2_R253W,kka2_1:2_253,Kka2,kka2_1:2,P00552,0.0516848,NO,253,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.356,-5.444,4.088,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.295029,0.0144195,0.0516848 beta-lactamase_I259H,beta-lactamase_259,TEM-1,beta-lactamase,P62593,0.0516948,NO,259,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.522,-4.977,3.455,5.28457,,E,B,1,-0.8,1.24,,64.34,HHH,-1.53267,0.221079,0.0070773,0.0516948 kka2_1:8_Q219Y,kka2_1:8_219,Kka2,kka2_1:8,P00552,0.0519048,NO,219,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-0.93,-4.01,3.08,,0.088,H,A,0.4,-0.85,0.897,,50,HPA,-1.05167,0.100394,0.00237913,0.0519048 kka2_1:8_Q219Y,kka2_1:8_219,Kka2,kka2_1:8,P00552,0.0519048,NO,219,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-0.93,-4.01,3.08,,0.088,H,A,0.4,-0.85,0.897,,50,HPA,-1.05167,0.100394,0.00237913,0.0519048 beta-lactamase_39_I245R,beta-lactamase_39_245,TEM-1,beta-lactamase_39,P62593,0.0519728,NO,245,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.0495842,0.00391032,0.0519728 beta-lactamase_2500_K71C,beta-lactamase_2500_71,TEM-1,beta-lactamase_2500,P62593,0.0520493,NO,71,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-0.8,-5.087,4.287,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.361275,0.00103192,0.0520493 kka2_1:4_A117F,kka2_1:4_117,Kka2,kka2_1:4,P00552,0.0520509,NO,117,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.828,-4.094,3.266,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.168804,0.00282984,0.0520509 beta-lactamase_C75H,beta-lactamase_75,TEM-1,beta-lactamase,P62593,0.0521126,NO,75,C,H,CH,Special,PositiveCharge,5.07,7.59,2.52,174,121,155,34,108.5,153.2,44.7,-1.245,-4.871,3.626,4.88171,,H,A,0.25,-0.87,0.876,,50,HOO,-1.24333,0.221079,0.0034616,0.0521126 beta-lactamase_T69K,beta-lactamase_69,TEM-1,beta-lactamase,P62593,0.0521126,NO,69,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-0.973,-3.493,2.52,5.16042,,G,A,0.69,-1.24,0.505,,93.01,PPH,-1.01833,0.221079,0.00127498,0.0521126 kka2_1:2_V75D,kka2_1:2_75,Kka2,kka2_1:2,P00552,0.0521692,NO,75,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-2.06,-4.066,2.006,,0.042,.,B,0.44,-0.2,2.815,,71.59,OHO,-1.563,0.295029,0.00693733,0.0521692 beta-lactamase_2500_L150R,beta-lactamase_2500_150,TEM-1,beta-lactamase_2500,P62593,0.0522384,NO,150,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.326,-3.982,2.656,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.361275,0.00463171,0.0522384 beta-lactamase_2500_N168L,beta-lactamase_2500_168,TEM-1,beta-lactamase_2500,P62593,0.0522867,NO,168,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-1.029,-3.516,2.487,,0.113,G,A,0.61,-0.4,2.9,,44.41,HPA,-1.13233,0.361275,0.00288667,0.0522867 beta-lactamase_156_M67P,beta-lactamase_156_67,TEM-1,beta-lactamase_156,P62593,0.0523488,NO,67,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-2.231,-4.072,1.841,,0.006,G,P,0.55,-0.81,1.463,,65.03,HHP,-1.502,0.111618,0.00409753,0.0523488 kka2_1:2_D62F,kka2_1:2_62,Kka2,kka2_1:2,P00552,0.0523949,NO,62,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.591,-4.401,2.81,,0.262,H,A,0.75,0.08,10.048,10.048,64.39,PAA,-1.77833,0.295029,0.00744243,0.0523949 kka2_1:2_L67Y,kka2_1:2_67,Kka2,kka2_1:2,P00552,0.0527273,NO,67,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.741,-3.966,3.225,,0.007,H,A,1.59,-0.66,,,,BHP,-1.42867,0.295029,0.00102787,0.0527273 PSD95pdz3_I327S,PSD95pdz3_327,PSD95pdz3,PSD95pdz3,P31016,0.0528444,NO,327,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.63,-3.292,1.662,5.7413,,,,,14.0388,,,,PHH,-1.50167,0.0758425,0.000998774,0.0528444 beta-lactamase_625_A132N,beta-lactamase_625_132,TEM-1,beta-lactamase_625,P62593,0.0528708,NO,132,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.9,-3.872,2.972,,,H,A,0.46,-0.93,0.316,,64.69,PHH,-1.138,0.213352,0.000962524,0.0528708 PSD95pdz3_L323K,PSD95pdz3_323,PSD95pdz3,PSD95pdz3,P31016,0.0529691,NO,323,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.347,-3.364,2.017,5.12397,,,,,13.8825,,,,OHO,-1.121,0.0758425,0.00104644,0.0529691 beta-lactamase_T178P,beta-lactamase_178,TEM-1,beta-lactamase,P62593,0.0530523,NO,178,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-0.791,-3.655,2.864,5.06452,0.029,E,B,0.3,-1.07,,,,APP,-0.947667,0.221079,0.000684366,0.0530523 kka2_1:8_F48I,kka2_1:8_48,Kka2,kka2_1:8,P00552,0.0530826,NO,48,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.453,-2.391,0.938,,0.296,E,B,1.62,-0.99,14.194,14.194,55.3,HHH,-1.444,0.100394,0.00475422,0.0530826 kka2_1:8_F48I,kka2_1:8_48,Kka2,kka2_1:8,P00552,0.0530826,NO,48,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.453,-2.391,0.938,,0.296,E,B,1.62,-0.99,14.194,14.194,55.3,HHH,-1.444,0.100394,0.00475422,0.0530826 kka2_1:1_G213Q,kka2_1:1_213,Kka2,kka2_1:1,P00552,0.0534421,NO,213,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.596,-4.153,3.557,,,E,b,0.29,-0.4,,,,HOH,-0.920333,0.520039,0.00187654,0.0534421 beta-lactamase_2500_N130H,beta-lactamase_2500_130,TEM-1,beta-lactamase_2500,P62593,0.0534695,NO,130,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-0.798,-4.005,3.207,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.361275,0.000683376,0.0534695 beta-lactamase_625_L79P,beta-lactamase_625_79,TEM-1,beta-lactamase_625,P62593,0.0535783,NO,79,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.842,-4.102,3.26,,0.007,H,A,0.55,-0.16,0.935,,50.35,HHP,-1.44333,0.213352,0.000947397,0.0535783 kka2_1:1_D157I,kka2_1:1_157,Kka2,kka2_1:1,P00552,0.0535983,NO,157,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.993,-4.127,3.134,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.520039,0.0042313,0.0535983 beta-lactamase_2500_D129L,beta-lactamase_2500_129,TEM-1,beta-lactamase_2500,P62593,0.0537278,NO,129,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.816,-3.806,2.99,,,,B,0.75,-0.69,1.29,,34.97,PAP,-0.818,0.361275,0.00109178,0.0537278 beta-lactamase_2500_F149P,beta-lactamase_2500_149,TEM-1,beta-lactamase_2500,P62593,0.0538752,NO,149,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.299,-4.282,2.983,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.361275,0.00418462,0.0538752 kka2_1:2_V36W,kka2_1:2_36,Kka2,kka2_1:2,P00552,0.0539082,NO,36,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-0.898,-5.395,4.497,,0.292,E,B,1.48,0.21,1.064,,52.27,HHH,-1.484,0.295029,0.00245633,0.0539082 beta-lactamase_2500_Y44Q,beta-lactamase_2500_44,TEM-1,beta-lactamase_2500,P62593,0.0539564,NO,44,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-2.547,-4.196,1.649,,,E,B,0.21,-0.45,2.184,,73.78,OHH,-1.86267,0.361275,0.00426364,0.0539564 beta-lactamase_625_N134P,beta-lactamase_625_134,TEM-1,beta-lactamase_625,P62593,0.054094,NO,134,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-0.879,-3.877,2.998,,0.138,H,A,0.61,-0.6,3.776,,53.15,HPH,-1.02233,0.213352,0.000644786,0.054094 kka2_1:2_P12W,kka2_1:2_12,Kka2,kka2_1:2,P00552,0.0541607,NO,12,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.853,-5.545,4.692,,,.,B,0.52,1.25,0.261,,48.11,POH,-1.80767,0.295029,0.00500011,0.0541607 beta-lactamase_V117D,beta-lactamase_117,TEM-1,beta-lactamase,P62593,0.0541629,NO,117,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.53,-4.116,2.586,5.33594,,H,A,1.19,-0.34,1.182,,65.03,PHB,-1.741,0.221079,0.00467906,0.0541629 beta-lactamase_2500_T69E,beta-lactamase_2500_69,TEM-1,beta-lactamase_2500,P62593,0.0541977,NO,69,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-0.973,-3.476,2.503,,,G,A,0.22,-1.24,2.05,,93.01,PPH,-1.01833,0.361275,0.00127498,0.0541977 beta-lactamase_2500_Y44T,beta-lactamase_2500_44,TEM-1,beta-lactamase_2500,P62593,0.0543143,NO,44,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-2.547,-2.836,0.289,,,E,B,0.21,-0.45,2.184,,73.78,OHH,-1.86267,0.361275,0.00426364,0.0543143 beta-lactamase_L188D,beta-lactamase_188,TEM-1,beta-lactamase,P62593,0.0545183,NO,188,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.166,-3.967,2.801,5.55434,,H,A,1.07,-0.3,1.574,,60.14,PHB,-1.47033,0.221079,0.00295687,0.0545183 beta-lactamase_156_V78P,beta-lactamase_156_78,TEM-1,beta-lactamase_156,P62593,0.0547334,NO,78,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.459,-4.126,2.667,,,H,A,0.44,-0.47,1.132,,63.64,HHH,-1.17833,0.111618,0.00492501,0.0547334 beta-lactamase_156_L136D,beta-lactamase_156_136,TEM-1,beta-lactamase_156,P62593,0.0547706,NO,136,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.232,-4.137,2.905,,,H,A,0.55,-0.34,1.04,,48.95,HHH,-1.088,0.111618,0.00442304,0.0547706 PSD95pdz3_I327Q,PSD95pdz3_327,PSD95pdz3,PSD95pdz3,P31016,0.0548386,NO,327,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.63,-4.031,2.401,5.7413,,,,,14.0388,,,,PHH,-1.50167,0.0758425,0.000998774,0.0548386 beta-lactamase_2500_D177W,beta-lactamase_2500_177,TEM-1,beta-lactamase_2500,P62593,0.0548853,NO,177,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.967,-5.545,4.578,,0.006,T,L,0.75,-1.02,4.131,,64.69,BAP,-0.873667,0.361275,0.000864022,0.0548853 kka2_1:2_S32E,kka2_1:2_32,Kka2,kka2_1:2,P00552,0.0550339,NO,32,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-0.804,-3.243,2.439,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.295029,0.00149998,0.0550339 beta-lactamase_156_K232W,beta-lactamase_156_232,TEM-1,beta-lactamase_156,P62593,0.0550709,NO,232,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.012,-5.365,4.353,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.111618,0.00313441,0.0550709 beta-lactamase_625_W227I,beta-lactamase_625_227,TEM-1,beta-lactamase_625,P62593,0.0551518,NO,227,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-0.982,-3.985,3.003,,0.272,,B,0.47,-0.29,2.533,,74.48,OHH,-1.595,0.213352,0.00226019,0.0551518 beta-lactamase_2500_S68D,beta-lactamase_2500_68,TEM-1,beta-lactamase_2500,P62593,0.055244,NO,68,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-0.913,-3.241,2.328,,0.064,G,A,0.27,-1.03,2.824,,64.69,HPP,-1.37233,0.361275,0.000800065,0.055244 PSD95pdz3_I327T,PSD95pdz3_327,PSD95pdz3,PSD95pdz3,P31016,0.0552748,NO,327,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.63,-3.103,1.473,5.7413,,,,,14.0388,,,,PHH,-1.50167,0.0758425,0.000998774,0.0552748 beta-lactamase_2500_V259R,beta-lactamase_2500_259,TEM-1,beta-lactamase_2500,P62593,0.0552777,NO,259,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.361275,0.0070773,0.0552777 beta-lactamase_2500_N130R,beta-lactamase_2500_130,TEM-1,beta-lactamase_2500,P62593,0.0554378,NO,130,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-0.798,-3.483,2.685,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.361275,0.000683376,0.0554378 kka2_1:1_R173W,kka2_1:1_173,Kka2,kka2_1:1,P00552,0.0554868,NO,173,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.407,-3.224,0.817,,0.308,H,A,0.16,-0.13,14.756,14.756,65.53,HBH,-1.70533,0.520039,0.00784999,0.0554868 beta-lactamase_2500_F64N,beta-lactamase_2500_64,TEM-1,beta-lactamase_2500,P62593,0.0555071,NO,64,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-0.841,-4.123,3.282,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.361275,0.000947691,0.0555071 kka2_1:4_M197N,kka2_1:4_197,Kka2,kka2_1:4,P00552,0.0555281,NO,197,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.707,-4.155,2.448,,0.121,E,B,0.55,-1.19,0.415,,65.53,HHH,-1.847,0.168804,0.00921295,0.0555281 beta-lactamase_2500_M184R,beta-lactamase_2500_184,TEM-1,beta-lactamase_2500,P62593,0.0558575,NO,184,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.593,-3.928,2.335,,,H,A,0.55,-0.87,2.893,,62.94,HHH,-1.41,0.361275,0.00356019,0.0558575 beta-lactamase_2500_N168M,beta-lactamase_2500_168,TEM-1,beta-lactamase_2500,P62593,0.0558787,NO,168,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-1.029,-4.683,3.654,,0.113,G,A,0.61,-0.4,2.9,,44.41,HPA,-1.13233,0.361275,0.00288667,0.0558787 beta-lactamase_2500_Y44S,beta-lactamase_2500_44,TEM-1,beta-lactamase_2500,P62593,0.0558798,NO,44,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-2.547,-3.605,1.058,,,E,B,0.21,-0.45,2.184,,73.78,OHH,-1.86267,0.361275,0.00426364,0.0558798 PSD95pdz3_I336W,PSD95pdz3_336,PSD95pdz3,PSD95pdz3,P31016,0.055898,NO,336,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.63,-5.004,3.374,5.11321,,,,,13.6363,,,,OHH,-1.38733,0.0758425,0.000887923,0.055898 beta-lactamase_625_D177M,beta-lactamase_625_177,TEM-1,beta-lactamase_625,P62593,0.0559349,NO,177,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.967,-4.928,3.961,,0.006,T,L,0.75,-1.02,1.333,,64.69,BAP,-0.873667,0.213352,0.000864022,0.0559349 kka2_1:8_G30N,kka2_1:8_30,Kka2,kka2_1:8,P00552,0.0560086,NO,30,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.596,-3.476,2.88,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.100394,0.00159208,0.0560086 kka2_1:8_G30N,kka2_1:8_30,Kka2,kka2_1:8,P00552,0.0560086,NO,30,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.596,-3.476,2.88,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.100394,0.00159208,0.0560086 PSD95pdz3_G329V,PSD95pdz3_329,PSD95pdz3,PSD95pdz3,P31016,0.0560849,NO,329,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.008,-3.435,2.427,4.7671,,,,,19.7075,,,,HOO,-1.16033,0.0758425,0.000974577,0.0560849 beta-lactamase_39_K71E,beta-lactamase_39_71,TEM-1,beta-lactamase_39,P62593,0.0560968,NO,71,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-0.8,-2.99,2.19,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.0495842,0.00103192,0.0560968 beta-lactamase_2500_R162V,beta-lactamase_2500_162,TEM-1,beta-lactamase_2500,P62593,0.0562131,NO,162,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.016,-3.642,2.626,,0.124,S,B,1.2,-0.37,6.199,,64.69,ABH,-1.25,0.361275,0.000561334,0.0562131 beta-lactamase_156_L136R,beta-lactamase_156_136,TEM-1,beta-lactamase_156,P62593,0.0563068,NO,136,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.232,-4.116,2.884,,,H,A,0.55,-0.34,1.04,,48.95,HHH,-1.088,0.111618,0.00442304,0.0563068 kka2_1:2_F133H,kka2_1:2_133,Kka2,kka2_1:2,P00552,0.0563302,NO,133,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-0.871,-4.414,3.543,,0.178,.,B,0.58,0.43,1.999,,42.42,OHA,-0.871667,0.295029,0.00182168,0.0563302 beta-lactamase_625_W227N,beta-lactamase_625_227,TEM-1,beta-lactamase_625,P62593,0.0563374,NO,227,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-0.982,-4.236,3.254,,0.272,,B,0.47,-0.29,2.533,,74.48,OHH,-1.595,0.213352,0.00226019,0.0563374 beta-lactamase_156_L79P,beta-lactamase_156_79,TEM-1,beta-lactamase_156,P62593,0.0563618,NO,79,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.842,-4.102,3.26,,0.007,H,A,0.55,-0.16,1.831,,50.35,HHP,-1.44333,0.111618,0.000947397,0.0563618 Ubiquitin_T9K,Ubiquitin_9,Uba1,Ubiquitin,P0CG48,0.0564516,NO,9,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.409,-3.491,2.082,5.24336,0.777,T,A,2.12,-0.12,2.705,,29.93,HPO,-1.50933,0.205827,0.000630716,0.0564516 kka2_1:4_G233W,kka2_1:4_233,Kka2,kka2_1:4,P00552,0.0564763,NO,233,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.748,-5.239,4.491,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.168804,0.00232366,0.0564763 kka2_1:4_T187Q,kka2_1:4_187,Kka2,kka2_1:4,P00552,0.0565279,NO,187,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.273,-4.098,2.825,,0.007,E,B,0.22,-0.85,2.73,,52.27,HPB,-1.06567,0.168804,0.00693073,0.0565279 beta-lactamase_39_A230P,beta-lactamase_39_230,TEM-1,beta-lactamase_39,P62593,0.0566113,NO,230,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.154,-3.805,2.651,,0.01,E,B,0.46,-1.17,1.171,,50,HHA,-1.079,0.0495842,0.00516841,0.0566113 beta-lactamase_2500_N134F,beta-lactamase_2500_134,TEM-1,beta-lactamase_2500,P62593,0.0567256,NO,134,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-0.879,-4.318,3.439,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.361275,0.000644786,0.0567256 beta-lactamase_625_L205H,beta-lactamase_625_205,TEM-1,beta-lactamase_625,P62593,0.0569614,NO,205,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.922,-4.828,3.906,,,H,A,0.55,-0.46,3.782,,42.31,PHH,-1.57767,0.213352,0.00255802,0.0569614 kka2_1:4_G233H,kka2_1:4_233,Kka2,kka2_1:4,P00552,0.0570062,NO,233,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.748,-4.708,3.96,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.168804,0.00232366,0.0570062 PSD95pdz3_L323E,PSD95pdz3_323,PSD95pdz3,PSD95pdz3,P31016,0.057082,NO,323,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.347,-3.572,2.225,5.12397,,,,,13.8825,,,,OHO,-1.121,0.0758425,0.00104644,0.057082 beta-lactamase_G76P,beta-lactamase_76,TEM-1,beta-lactamase,P62593,0.0571245,NO,76,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.189,-3.852,2.663,4.73862,,H,A,2.05,-0.67,3.059,,67.83,OOH,-1.22267,0.221079,0.00476637,0.0571245 beta-lactamase_I278S,beta-lactamase_278,TEM-1,beta-lactamase,P62593,0.0571245,NO,278,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.348,-3.632,2.284,5.35127,0.015,H,A,0.77,-0.85,2.718,,63.29,AHO,-1.41833,0.221079,0.0310297,0.0571245 beta-lactamase_M209N,beta-lactamase_209,TEM-1,beta-lactamase,P62593,0.0571245,NO,209,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.442,-4.092,2.65,5.44502,,H,A,1.75,-0.97,1.402,,64.69,HHA,-1.52633,0.221079,0.00625021,0.0571245 beta-lactamase_2500_V78G,beta-lactamase_2500_78,TEM-1,beta-lactamase_2500,P62593,0.0571537,NO,78,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.459,-2.817,1.358,,,H,A,0.44,-0.47,31.376,31.376,63.64,HHH,-1.17833,0.361275,0.00492501,0.0571537 kka2_1:2_N195A,kka2_1:2_195,Kka2,kka2_1:2,P00552,0.0572777,NO,195,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-0.836,-3.354,2.518,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.295029,0.00276134,0.0572777 kka2_1:4_V36H,kka2_1:4_36,Kka2,kka2_1:4,P00552,0.0574445,NO,36,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-0.898,-4.978,4.08,,0.292,E,B,0.44,0.21,0.278,,52.27,HHH,-1.484,0.168804,0.00245633,0.0574445 kka2_1:4_G233F,kka2_1:4_233,Kka2,kka2_1:4,P00552,0.0582165,NO,233,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.748,-4.365,3.617,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.168804,0.00232366,0.0582165 beta-lactamase_39_V259R,beta-lactamase_39_259,TEM-1,beta-lactamase_39,P62593,0.0583029,NO,259,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.0495842,0.0070773,0.0583029 beta-lactamase_39_F64P,beta-lactamase_39_64,TEM-1,beta-lactamase_39,P62593,0.0583094,NO,64,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-0.841,-4.33,3.489,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.0495842,0.000947691,0.0583094 beta-lactamase_2500_L136Y,beta-lactamase_2500_136,TEM-1,beta-lactamase_2500,P62593,0.0583218,NO,136,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.232,-4.051,2.819,,,H,A,0.55,-0.34,1.36,,48.95,HHH,-1.088,0.361275,0.00442304,0.0583218 beta-lactamase_2500_K71R,beta-lactamase_2500_71,TEM-1,beta-lactamase_2500,P62593,0.0583721,NO,71,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-0.8,-3.033,2.233,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.361275,0.00103192,0.0583721 beta-lactamase_2500_P181D,beta-lactamase_2500_181,TEM-1,beta-lactamase_2500,P62593,0.0584676,NO,181,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.813,-3.518,2.705,,,H,A,0.52,-1.14,1.946,,61.54,HOH,-1.795,0.361275,0.000703122,0.0584676 kka2_1:2_A237G,kka2_1:2_237,Kka2,kka2_1:2,P00552,0.0585052,NO,237,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.12,-3.628,1.508,,0.068,H,A,0.46,-0.71,2.369,,92.05,HHA,-2.10433,0.295029,0.012257,0.0585052 kka2_1:2_W91P,kka2_1:2_91,Kka2,kka2_1:2,P00552,0.0586019,NO,91,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-1.178,-4.336,3.158,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.295029,0.00358653,0.0586019 kka2_1:4_D190F,kka2_1:4_190,Kka2,kka2_1:4,P00552,0.0587345,NO,190,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.708,-4.32,3.612,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.168804,0.00247989,0.0587345 PSD95pdz3_F340P,PSD95pdz3_340,PSD95pdz3,PSD95pdz3,P31016,0.0587645,NO,340,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.524,-4.011,2.487,5.79283,,,,,11.8045,,,,PHH,-1.55767,0.0758425,0.000836987,0.0587645 kka2_1:4_I228D,kka2_1:4_228,Kka2,kka2_1:4,P00552,0.0588905,NO,228,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.142,-4.061,2.919,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.168804,0.00458834,0.0588905 kka2_1:8_L232A,kka2_1:8_232,Kka2,kka2_1:8,P00552,0.0589088,NO,232,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.514,-3.306,1.792,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.100394,0.00800103,0.0589088 kka2_1:8_L232A,kka2_1:8_232,Kka2,kka2_1:8,P00552,0.0589088,NO,232,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.514,-3.306,1.792,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.100394,0.00800103,0.0589088 kka2_1:1_L241T,kka2_1:1_241,Kka2,kka2_1:1,P00552,0.0589924,NO,241,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.158,-3.592,2.434,,0.08,H,A,0.55,-0.82,1.685,,63.26,HHH,-1.58533,0.520039,0.0117299,0.0589924 kka2_1:2_H188I,kka2_1:2_188,Kka2,kka2_1:2,P00552,0.0591013,NO,188,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-0.913,-4.062,3.149,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.295029,0.00273139,0.0591013 beta-lactamase_625_P65W,beta-lactamase_625_65,TEM-1,beta-lactamase_625,P62593,0.0591068,NO,65,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.894,-5.47,4.576,,0.098,E,B,0.52,-0.62,0.3,,40.56,HOH,-1.03233,0.213352,0.00152776,0.0591068 beta-lactamase_625_S233F,beta-lactamase_625_233,TEM-1,beta-lactamase_625,P62593,0.0591926,NO,233,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.886,-4.226,2.34,,0.016,E,B,0.27,-1.01,1.773,,77.62,BPO,-1.17267,0.213352,0.00311415,0.0591926 beta-lactamase_2500_W288A,beta-lactamase_2500_288,TEM-1,beta-lactamase_2500,P62593,0.05922,NO,288,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,,,,,,,,,,,,,BHO,,0.361275,,0.05922 beta-lactamase_2500_P65E,beta-lactamase_2500_65,TEM-1,beta-lactamase_2500,P62593,0.0592761,NO,65,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.894,-3.524,2.63,,0.098,E,B,0.52,-0.62,0.3,,40.56,HOH,-1.03233,0.361275,0.00152776,0.0592761 kka2_1:2_L232T,kka2_1:2_232,Kka2,kka2_1:2,P00552,0.0592969,NO,232,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.514,-3.677,2.163,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.295029,0.00800103,0.0592969 beta-lactamase_625_K232M,beta-lactamase_625_232,TEM-1,beta-lactamase_625,P62593,0.0594024,NO,232,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.012,-4.522,3.51,,,E,B,2.34,-1.1,1.992,,65.03,ABP,-1.238,0.213352,0.00313441,0.0594024 kka2_1:1_R173D,kka2_1:1_173,Kka2,kka2_1:1,P00552,0.0594777,NO,173,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.407,-2.431,0.024,,0.308,H,A,0.16,-0.13,14.756,14.756,65.53,HBH,-1.70533,0.520039,0.00784999,0.0594777 beta-lactamase_2500_P181F,beta-lactamase_2500_181,TEM-1,beta-lactamase_2500,P62593,0.0596007,NO,181,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.813,-4.48,3.667,,,H,A,0.52,-1.14,1.946,,61.54,HOH,-1.795,0.361275,0.000703122,0.0596007 beta-lactamase_39_K71F,beta-lactamase_39_71,TEM-1,beta-lactamase_39,P62593,0.0596288,NO,71,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-0.8,-4.292,3.492,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.0495842,0.00103192,0.0596288 beta-lactamase_V257D,beta-lactamase_257,TEM-1,beta-lactamase,P62593,0.0596304,NO,257,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.533,-3.988,2.455,5.31999,,E,B,0.96,-0.7,1.463,,58.74,HHH,-1.70967,0.221079,0.00756629,0.0596304 beta-lactamase_2500_G234P,beta-lactamase_2500_234,TEM-1,beta-lactamase_2500,P62593,0.0598341,NO,234,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.62,-3.88,3.26,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.361275,0.000889577,0.0598341 beta-lactamase_625_I245Q,beta-lactamase_625_245,TEM-1,beta-lactamase_625,P62593,0.0598474,NO,245,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.213352,0.00391032,0.0598474 kka2_1:1_A176F,kka2_1:1_176,Kka2,kka2_1:1,P00552,0.0599465,NO,176,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.621,-4.399,2.778,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.520039,0.0083587,0.0599465 beta-lactamase_156_G43L,beta-lactamase_156_43,TEM-1,beta-lactamase_156,P62593,0.0600177,NO,43,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.62,-3.808,3.188,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.111618,0.00120151,0.0600177 beta-lactamase_156_W227K,beta-lactamase_156_227,TEM-1,beta-lactamase_156,P62593,0.0601048,NO,227,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-0.982,-3.931,2.949,,0.272,,B,0.47,-0.29,2.533,,74.48,OHH,-1.595,0.111618,0.00226019,0.0601048 kka2_1:1_A172F,kka2_1:1_172,Kka2,kka2_1:1,P00552,0.0602594,NO,172,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.757,-4.4,2.643,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.520039,0.0079265,0.0602594 beta-lactamase_39_S128Y,beta-lactamase_39_128,TEM-1,beta-lactamase_39,P62593,0.0603324,NO,128,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-0.84,-4.162,3.322,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.0495842,0.00071483,0.0603324 beta-lactamase_L191D,beta-lactamase_191,TEM-1,beta-lactamase,P62593,0.0603822,NO,191,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.087,-4.092,3.005,5.72226,,H,A,1.07,0.09,1.23,,63.29,BHH,-1.445,0.221079,0.00263549,0.0603822 kka2_1:4_D157I,kka2_1:4_157,Kka2,kka2_1:4,P00552,0.0607256,NO,157,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.993,-4.127,3.134,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.168804,0.0042313,0.0607256 beta-lactamase_156_S68W,beta-lactamase_156_68,TEM-1,beta-lactamase_156,P62593,0.0608484,NO,68,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-0.913,-5.371,4.458,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.111618,0.000800065,0.0608484 kka2_1:4_N195Q,kka2_1:4_195,Kka2,kka2_1:4,P00552,0.0609482,NO,195,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-0.836,-3.726,2.89,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.168804,0.00276134,0.0609482 beta-lactamase_2500_A185K,beta-lactamase_2500_185,TEM-1,beta-lactamase_2500,P62593,0.0609688,NO,185,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.406,-3.666,2.26,,,H,A,0.46,-1.02,2.999,,65.03,HHP,-1.84033,0.361275,0.00467449,0.0609688 beta-lactamase_W227R,beta-lactamase_227,TEM-1,beta-lactamase,P62593,0.0610562,NO,227,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-0.982,-4.182,3.2,4.86393,0.272,,B,0.99,-0.29,1.37,,74.48,OHH,-1.595,0.221079,0.00226019,0.0610562 kka2_1:8_F240N,kka2_1:8_240,Kka2,kka2_1:8,P00552,0.0612107,NO,240,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-0.911,-4.185,3.274,,,H,A,1.62,-1.21,0.697,,50.38,BHH,-1.67267,0.100394,0.00552543,0.0612107 kka2_1:8_F240N,kka2_1:8_240,Kka2,kka2_1:8,P00552,0.0612107,NO,240,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-0.911,-4.185,3.274,,,H,A,1.62,-1.21,0.697,,50.38,BHH,-1.67267,0.100394,0.00552543,0.0612107 beta-lactamase_39_A133W,beta-lactamase_39_133,TEM-1,beta-lactamase_39,P62593,0.0612332,NO,133,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.186,-5.303,4.117,,,H,A,0.46,-0.86,0.373,,67.83,HHP,-0.988333,0.0495842,0.00468022,0.0612332 beta-lactamase_2500_Y262D,beta-lactamase_2500_262,TEM-1,beta-lactamase_2500,P62593,0.0612834,NO,262,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.361275,0.00853516,0.0612834 beta-lactamase_156_P181Y,beta-lactamase_156_181,TEM-1,beta-lactamase_156,P62593,0.0613118,NO,181,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.813,-4.385,3.572,,,H,A,0.52,-1.14,1.078,,61.54,HOH,-1.795,0.111618,0.000703122,0.0613118 beta-lactamase_2500_K232L,beta-lactamase_2500_232,TEM-1,beta-lactamase_2500,P62593,0.0614612,NO,232,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.012,-3.401,2.389,,,E,B,2.34,-1.1,3.048,,65.03,ABP,-1.238,0.361275,0.00313441,0.0614612 beta-lactamase_2500_G43K,beta-lactamase_2500_43,TEM-1,beta-lactamase_2500,P62593,0.0614916,NO,43,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.62,-3.682,3.062,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.361275,0.00120151,0.0614916 kka2_1:2_G30N,kka2_1:2_30,Kka2,kka2_1:2,P00552,0.0616443,NO,30,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.596,-3.476,2.88,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.295029,0.00159208,0.0616443 beta-lactamase_F14D,beta-lactamase_14,TEM-1,beta-lactamase,P62593,0.0617785,NO,14,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-2.736,-3.944,1.208,,,,,,,1.537,,93.01,HHH,-2.26133,0.221079,0.00277095,0.0617785 kka2_1:8_L174E,kka2_1:8_174,Kka2,kka2_1:8,P00552,0.0617837,NO,174,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.952,-3.9,2.948,,,H,A,1.59,-0.31,1.204,,51.89,BHB,-2.08533,0.100394,0.00438501,0.0617837 kka2_1:8_L174E,kka2_1:8_174,Kka2,kka2_1:8,P00552,0.0617837,NO,174,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.952,-3.9,2.948,,,H,A,1.59,-0.31,1.204,,51.89,BHB,-2.08533,0.100394,0.00438501,0.0617837 PSD95pdz3_L379E,PSD95pdz3_379,PSD95pdz3,PSD95pdz3,P31016,0.0618803,NO,379,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.347,-3.572,2.225,5.37777,,,,,16.8762,,,,HHB,-1.35667,0.0758425,0.00029733,0.0618803 kka2_1:2_R173Y,kka2_1:2_173,Kka2,kka2_1:2,P00552,0.0620207,NO,173,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.407,-3.028,0.621,,0.308,H,A,0.16,-0.13,15.389,15.389,65.53,HBH,-1.70533,0.295029,0.00784999,0.0620207 kka2_1:2_V49P,kka2_1:2_49,Kka2,kka2_1:2,P00552,0.0620395,NO,49,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.614,-4.128,2.514,,,E,B,0.44,-0.77,1.233,,64.39,HHB,-1.3,0.295029,0.00615685,0.0620395 kka2_1:1_A78G,kka2_1:1_78,Kka2,kka2_1:1,P00552,0.0620661,NO,78,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.744,-3.281,1.537,,0.078,.,B,0.46,-0.53,0.206,,56.06,OHH,-1.863,0.520039,0.00457299,0.0620661 kka2_1:8_L102Y,kka2_1:8_102,Kka2,kka2_1:8,P00552,0.0620698,NO,102,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.804,-3.989,3.185,,,T,A,1.59,-1.17,0.97,,42.42,AHH,-1.398,0.100394,0.00201332,0.0620698 kka2_1:8_L102Y,kka2_1:8_102,Kka2,kka2_1:8,P00552,0.0620698,NO,102,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.804,-3.989,3.185,,,T,A,1.59,-1.17,0.97,,42.42,AHH,-1.398,0.100394,0.00201332,0.0620698 kka2_1:2_L259F,kka2_1:2_259,Kka2,kka2_1:2,P00552,0.0622246,NO,259,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.088,-3.817,2.729,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.295029,0.0206964,0.0622246 beta-lactamase_625_S233E,beta-lactamase_625_233,TEM-1,beta-lactamase_625,P62593,0.0623647,NO,233,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.886,-3.479,1.593,,0.016,E,B,0.27,-1.01,1.773,,77.62,BPO,-1.17267,0.213352,0.00311415,0.0623647 kka2_1:1_V80W,kka2_1:1_80,Kka2,kka2_1:1,P00552,0.0624705,NO,80,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.144,-5.458,4.314,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.520039,0.00488211,0.0624705 kka2_1:2_I207R,kka2_1:2_207,Kka2,kka2_1:2,P00552,0.0626194,NO,207,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.175,-4.245,3.07,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.295029,0.00611824,0.0626194 kka2_1:4_P76I,kka2_1:4_76,Kka2,kka2_1:4,P00552,0.062632,NO,76,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.449,-3.871,2.422,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.168804,0.00625685,0.062632 kka2_1:4_M197P,kka2_1:4_197,Kka2,kka2_1:4,P00552,0.0626875,NO,197,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.707,-4.141,2.434,,0.121,E,B,0.55,-1.19,0.415,,65.53,HHH,-1.847,0.168804,0.00921295,0.0626875 beta-lactamase_N130H,beta-lactamase_130,TEM-1,beta-lactamase,P62593,0.0627413,NO,130,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-0.798,-4.005,3.207,5.26686,0.069,H,A,1.08,-0.74,,,,APP,-0.980667,0.221079,0.000683376,0.0627413 kka2_1:8_D62I,kka2_1:8_62,Kka2,kka2_1:8,P00552,0.0629266,NO,62,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.591,-4.096,2.505,,0.262,H,A,0.29,0.08,5.58,,64.39,PAA,-1.77833,0.100394,0.00744243,0.0629266 kka2_1:8_D62I,kka2_1:8_62,Kka2,kka2_1:8,P00552,0.0629266,NO,62,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.591,-4.096,2.505,,0.262,H,A,0.29,0.08,5.58,,64.39,PAA,-1.77833,0.100394,0.00744243,0.0629266 kka2_1:4_G213H,kka2_1:4_213,Kka2,kka2_1:4,P00552,0.063113,NO,213,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.596,-4.708,4.112,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.168804,0.00187654,0.063113 kka2_1:4_Y257R,kka2_1:4_257,Kka2,kka2_1:4,P00552,0.0632411,NO,257,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-1.064,-4.088,3.024,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.168804,0.0148191,0.0632411 beta-lactamase_S233I,beta-lactamase_233,TEM-1,beta-lactamase,P62593,0.0633893,NO,233,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.886,-3.784,1.898,4.98121,0.016,E,B,0.48,-1.01,5.361,,77.62,BPO,-1.17267,0.221079,0.00311415,0.0633893 beta-lactamase_2500_Y44K,beta-lactamase_2500_44,TEM-1,beta-lactamase_2500,P62593,0.0633946,NO,44,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-2.547,-3.823,1.276,,,E,B,0.21,-0.45,2.184,,73.78,OHH,-1.86267,0.361275,0.00426364,0.0633946 beta-lactamase_39_N130F,beta-lactamase_39_130,TEM-1,beta-lactamase_39,P62593,0.0634295,NO,130,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-0.798,-4.292,3.494,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.0495842,0.000683376,0.0634295 beta-lactamase_V42E,beta-lactamase_42,TEM-1,beta-lactamase,P62593,0.0634455,NO,42,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.564,-3.88,2.316,5.27904,0.017,E,B,1.64,-0.51,2.024,,63.99,BHO,-1.042,0.221079,0.00404515,0.0634455 kka2_1:4_K50A,kka2_1:4_50,Kka2,kka2_1:4,P00552,0.0634971,NO,50,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-0.833,-3.129,2.296,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.168804,0.00138626,0.0634971 kka2_1:2_L232E,kka2_1:2_232,Kka2,kka2_1:2,P00552,0.0635226,NO,232,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.514,-3.993,2.479,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.295029,0.00800103,0.0635226 beta-lactamase_2500_V259G,beta-lactamase_2500_259,TEM-1,beta-lactamase_2500,P62593,0.0635838,NO,259,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.361275,0.0070773,0.0635838 kka2_1:4_A78H,kka2_1:4_78,Kka2,kka2_1:4,P00552,0.0636553,NO,78,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.744,-4.753,3.009,,0.078,.,B,0.46,-0.53,0.594,,56.06,OHH,-1.863,0.168804,0.00457299,0.0636553 beta-lactamase_625_W227R,beta-lactamase_625_227,TEM-1,beta-lactamase_625,P62593,0.0638694,NO,227,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-0.982,-4.182,3.2,,0.272,,B,0.47,-0.29,2.533,,74.48,OHH,-1.595,0.213352,0.00226019,0.0638694 kka2_1:2_V198F,kka2_1:2_198,Kka2,kka2_1:2,P00552,0.0638731,NO,198,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.719,-4.163,2.444,,0.05,E,B,1.48,-0.95,1.074,,56.06,HHA,-1.88667,0.295029,0.00835002,0.0638731 beta-lactamase_156_V42K,beta-lactamase_156_42,TEM-1,beta-lactamase_156,P62593,0.0638785,NO,42,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.564,-3.817,2.253,,0.017,E,B,0.44,-0.51,2.576,,63.99,BHO,-1.042,0.111618,0.00404515,0.0638785 beta-lactamase_2500_M184E,beta-lactamase_2500_184,TEM-1,beta-lactamase_2500,P62593,0.0638858,NO,184,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.593,-3.708,2.115,,,H,A,0.55,-0.87,2.893,,62.94,HHH,-1.41,0.361275,0.00356019,0.0638858 kka2_1:2_W24N,kka2_1:2_24,Kka2,kka2_1:2,P00552,0.0638972,NO,24,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-1.779,-4.301,2.522,,0.477,E,B,1.51,-0.21,2.666,,56.06,AHH,-2.24467,0.295029,0.00631564,0.0638972 kka2_1:4_V198P,kka2_1:4_198,Kka2,kka2_1:4,P00552,0.0641079,NO,198,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.719,-3.911,2.192,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.168804,0.00835002,0.0641079 beta-lactamase_2500_V78P,beta-lactamase_2500_78,TEM-1,beta-lactamase_2500,P62593,0.0641591,NO,78,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.459,-4.126,2.667,,,H,A,0.44,-0.47,31.376,31.376,63.64,HHH,-1.17833,0.361275,0.00492501,0.0641591 beta-lactamase_39_S68H,beta-lactamase_39_68,TEM-1,beta-lactamase_39,P62593,0.064165,NO,68,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-0.913,-4.418,3.505,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.0495842,0.000800065,0.064165 kka2_1:1_V80Y,kka2_1:1_80,Kka2,kka2_1:1,P00552,0.0642709,NO,80,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.144,-4.109,2.965,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.520039,0.00488211,0.0642709 beta-lactamase_K232S,beta-lactamase_232,TEM-1,beta-lactamase,P62593,0.0643069,NO,232,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.012,-3.258,2.246,5.18286,,E,B,2.92,-1.1,1.174,,65.03,ABP,-1.238,0.221079,0.00313441,0.0643069 kka2_1:8_L193E,kka2_1:8_193,Kka2,kka2_1:8,P00552,0.0643496,NO,193,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.983,-3.783,2.8,,,G,A,1.59,-1.03,2.234,,65.53,OHO,-0.965333,0.100394,0.00480179,0.0643496 kka2_1:8_L193E,kka2_1:8_193,Kka2,kka2_1:8,P00552,0.0643496,NO,193,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.983,-3.783,2.8,,,G,A,1.59,-1.03,2.234,,65.53,OHO,-0.965333,0.100394,0.00480179,0.0643496 kka2_1:4_M197S,kka2_1:4_197,Kka2,kka2_1:4,P00552,0.064378,NO,197,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.707,-3.643,1.936,,0.121,E,B,0.55,-1.19,0.415,,65.53,HHH,-1.847,0.168804,0.00921295,0.064378 beta-lactamase_625_P181W,beta-lactamase_625_181,TEM-1,beta-lactamase_625,P62593,0.0644736,NO,181,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.813,-5.545,4.732,,,H,A,0.52,-1.14,1.797,,61.54,HOH,-1.795,0.213352,0.000703122,0.0644736 beta-lactamase_I256D,beta-lactamase_256,TEM-1,beta-lactamase,P62593,0.0644807,NO,256,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.621,-4.095,2.474,5.3196,,E,B,1,-0.84,1.615,,73.08,BHH,-1.80667,0.221079,0.00710634,0.0644807 Ubiquitin_K6P,Ubiquitin_6,Uba1,Ubiquitin,P0CG48,0.0645161,NO,6,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.093,-3.692,2.599,4.84211,0.35,E,B,1.82,-0.62,1.502,,71.82,HBP,-1.36133,0.205827,0.000784795,0.0645161 Ubiquitin_L69K,Ubiquitin_69,Uba1,Ubiquitin,P0CG48,0.0645161,NO,69,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.445,-3.622,2.177,4.75624,0.051,E,B,2.89,-0.94,7.106,,34.31,BHH,-1.72933,0.205827,0.000919136,0.0645161 beta-lactamase_625_A133N,beta-lactamase_625_133,TEM-1,beta-lactamase_625,P62593,0.0645647,NO,133,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.186,-3.758,2.572,,,H,A,0.46,-0.86,0.373,,67.83,HHP,-0.988333,0.213352,0.00468022,0.0645647 Pab1_F173N,Pab1_173,Pab1,Pab1,P04147,0.064626,NO,173,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.477,-3.905,2.428,,,E,B,0.87,-0.16,1.636,,63.26,BHA,-1.36967,0.175299,0.00148779,0.064626 kka2_1:2_Y257N,kka2_1:2_257,Kka2,kka2_1:2,P00552,0.0646425,NO,257,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-1.064,-4.053,2.989,,0.022,H,A,0.21,-0.88,0.833,,52.65,HHB,-1.39333,0.295029,0.0148191,0.0646425 beta-lactamase_625_F64K,beta-lactamase_625_64,TEM-1,beta-lactamase_625,P62593,0.0648144,NO,64,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-0.841,-3.907,3.066,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.213352,0.000947691,0.0648144 kka2_1:1_G74D,kka2_1:1_74,Kka2,kka2_1:1,P00552,0.0650537,NO,74,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.18,-1.88,0.7,,0.621,T,l,0.75,0.2,15.356,15.356,64.39,POH,-1.91667,0.520039,0.00587035,0.0650537 beta-lactamase_625_M66R,beta-lactamase_625_66,TEM-1,beta-lactamase_625,P62593,0.0651135,NO,66,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.362,-3.923,2.561,,0.013,,A,0.55,-0.7,1.659,,73.08,OHH,-1.49567,0.213352,0.00412876,0.0651135 beta-lactamase_2500_S128R,beta-lactamase_2500_128,TEM-1,beta-lactamase_2500,P62593,0.0651394,NO,128,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-0.84,-3.708,2.868,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.361275,0.00071483,0.0651394 kka2_1:4_A191K,kka2_1:4_191,Kka2,kka2_1:4,P00552,0.0651919,NO,191,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.831,-3.519,2.688,,,.,b,0.46,-0.94,2.046,,50,AHO,-0.868667,0.168804,0.00338807,0.0651919 kka2_1:8_V214N,kka2_1:8_214,Kka2,kka2_1:8,P00552,0.0652005,NO,214,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.261,-4.229,2.968,,0.117,E,B,1.48,-0.31,1.859,,64.39,OHH,-0.941667,0.100394,0.00692782,0.0652005 kka2_1:8_V214N,kka2_1:8_214,Kka2,kka2_1:8,P00552,0.0652005,NO,214,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.261,-4.229,2.968,,0.117,E,B,1.48,-0.31,1.859,,64.39,OHH,-0.941667,0.100394,0.00692782,0.0652005 gb1_E253D,gb1_253,gb1,gb1,P06654,0.0652439,NO,253,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.71,-3.067,1.357,,,,,,,0.529,,11.83,HAB,-1.54433,0.177985,0.00141452,0.0652439 gb1_E253G,gb1_253,gb1,gb1,P06654,0.0652439,NO,253,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.71,-3.369,1.659,,,,,,,0.529,,11.83,HAB,-1.54433,0.177985,0.00141452,0.0652439 gb1_E253H,gb1_253,gb1,gb1,P06654,0.0652439,NO,253,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.71,-4.323,2.613,,,,,,,0.529,,11.83,HAB,-1.54433,0.177985,0.00141452,0.0652439 gb1_E253I,gb1_253,gb1,gb1,P06654,0.0652439,NO,253,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.71,-3.108,1.398,,,,,,,0.529,,11.83,HAB,-1.54433,0.177985,0.00141452,0.0652439 gb1_E253N,gb1_253,gb1,gb1,P06654,0.0652439,NO,253,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.71,-3.54,1.83,,,,,,,0.529,,11.83,HAB,-1.54433,0.177985,0.00141452,0.0652439 gb1_E253T,gb1_253,gb1,gb1,P06654,0.0652439,NO,253,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.71,-3.232,1.522,,,,,,,0.529,,11.83,HAB,-1.54433,0.177985,0.00141452,0.0652439 gb1_E253V,gb1_253,gb1,gb1,P06654,0.0652439,NO,253,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.71,-2.946,1.236,,,,,,,0.529,,11.83,HAB,-1.54433,0.177985,0.00141452,0.0652439 gb1_E253Y,gb1_253,gb1,gb1,P06654,0.0652439,NO,253,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.71,-3.855,2.145,,,,,,,0.529,,11.83,HAB,-1.54433,0.177985,0.00141452,0.0652439 gb1_G267I,gb1_267,gb1,gb1,P06654,0.0652439,NO,267,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.676,-3.347,1.671,,,,,,,1.361,,12.72,AOA,-1.61833,0.177985,0.00264655,0.0652439 gb1_K257A,gb1_257,gb1,gb1,P06654,0.0652439,NO,257,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.775,-2.966,1.191,,,,,,,0.896,,37.28,HBP,-1.70367,0.177985,0.00640304,0.0652439 gb1_K257D,gb1_257,gb1,gb1,P06654,0.0652439,NO,257,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.775,-3.34,1.565,,,,,,,0.896,,37.28,HBP,-1.70367,0.177985,0.00640304,0.0652439 gb1_K257E,gb1_257,gb1,gb1,P06654,0.0652439,NO,257,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.775,-2.861,1.086,,,,,,,0.896,,37.28,HBP,-1.70367,0.177985,0.00640304,0.0652439 gb1_K257F,gb1_257,gb1,gb1,P06654,0.0652439,NO,257,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.775,-4.18,2.405,,,,,,,0.896,,37.28,HBP,-1.70367,0.177985,0.00640304,0.0652439 gb1_K257G,gb1_257,gb1,gb1,P06654,0.0652439,NO,257,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.775,-3.247,1.472,,,,,,,0.896,,37.28,HBP,-1.70367,0.177985,0.00640304,0.0652439 gb1_K257S,gb1_257,gb1,gb1,P06654,0.0652439,NO,257,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.775,-3.119,1.344,,,,,,,0.896,,37.28,HBP,-1.70367,0.177985,0.00640304,0.0652439 gb1_K257V,gb1_257,gb1,gb1,P06654,0.0652439,NO,257,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.775,-3.487,1.712,,,,,,,0.896,,37.28,HBP,-1.70367,0.177985,0.00640304,0.0652439 gb1_N261P,gb1_261,gb1,gb1,P06654,0.0652439,NO,261,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-1.863,-3.613,1.75,,,,,,,1.191,,44.87,HPA,-2.16033,0.177985,0.0061875,0.0652439 gb1_W269D,gb1_269,gb1,gb1,P06654,0.0652439,NO,269,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-1.198,-3.921,2.723,,,,,,,,,,AHP,-2.08867,0.177985,0.00270706,0.0652439 gb1_W269E,gb1_269,gb1,gb1,P06654,0.0652439,NO,269,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-1.198,-3.667,2.469,,,,,,,,,,AHP,-2.08867,0.177985,0.00270706,0.0652439 gb1_W269I,gb1_269,gb1,gb1,P06654,0.0652439,NO,269,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-1.198,-3.787,2.589,,,,,,,,,,AHP,-2.08867,0.177985,0.00270706,0.0652439 gb1_W269K,gb1_269,gb1,gb1,P06654,0.0652439,NO,269,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-1.198,-3.684,2.486,,,,,,,,,,AHP,-2.08867,0.177985,0.00270706,0.0652439 gb1_W269M,gb1_269,gb1,gb1,P06654,0.0652439,NO,269,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-1.198,-4.257,3.059,,,,,,,,,,AHP,-2.08867,0.177985,0.00270706,0.0652439 gb1_W269N,gb1_269,gb1,gb1,P06654,0.0652439,NO,269,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-1.198,-4.125,2.927,,,,,,,,,,AHP,-2.08867,0.177985,0.00270706,0.0652439 gb1_W269P,gb1_269,gb1,gb1,P06654,0.0652439,NO,269,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-1.198,-4.107,2.909,,,,,,,,,,AHP,-2.08867,0.177985,0.00270706,0.0652439 gb1_W269Q,gb1_269,gb1,gb1,P06654,0.0652439,NO,269,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-1.198,-3.901,2.703,,,,,,,,,,AHP,-2.08867,0.177985,0.00270706,0.0652439 gb1_W269S,gb1_269,gb1,gb1,P06654,0.0652439,NO,269,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-1.198,-3.613,2.415,,,,,,,,,,AHP,-2.08867,0.177985,0.00270706,0.0652439 gb1_W269V,gb1_269,gb1,gb1,P06654,0.0652439,NO,269,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-1.198,-3.531,2.333,,,,,,,,,,AHP,-2.08867,0.177985,0.00270706,0.0652439 beta-lactamase_M1P,beta-lactamase_1,TEM-1,beta-lactamase,P62593,0.0652689,NO,1,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.998,-3.561,1.563,,,,,,,,,,OHP,-1.97,0.221079,0.00162771,0.0652689 kka2_1:4_L94G,kka2_1:4_94,Kka2,kka2_1:4,P00552,0.0653838,NO,94,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.618,-3.801,2.183,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.168804,0.00520888,0.0653838 kka2_1:2_N195Q,kka2_1:2_195,Kka2,kka2_1:2,P00552,0.0654181,NO,195,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-0.836,-3.726,2.89,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.295029,0.00276134,0.0654181 PSD95pdz3_G329Y,PSD95pdz3_329,PSD95pdz3,PSD95pdz3,P31016,0.0654324,NO,329,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.008,-4.069,3.061,4.7671,,,,,19.7075,,,,HOO,-1.16033,0.0758425,0.000974577,0.0654324 beta-lactamase_2500_L248S,beta-lactamase_2500_248,TEM-1,beta-lactamase_2500,P62593,0.0655274,NO,248,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.361275,0.00428493,0.0655274 kka2_1:4_G95W,kka2_1:4_95,Kka2,kka2_1:4,P00552,0.0655764,NO,95,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-2.403,-5.488,3.085,,0.126,E,B,0.29,-0.74,0.359,,71.59,HOA,-2.198,0.168804,0.00743616,0.0655764 kka2_1:2_G74Y,kka2_1:2_74,Kka2,kka2_1:2,P00552,0.0656153,NO,74,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.18,-4.468,3.288,,0.621,T,l,0.75,0.2,1.446,,64.39,POH,-1.91667,0.295029,0.00587035,0.0656153 beta-lactamase_39_A132R,beta-lactamase_39_132,TEM-1,beta-lactamase_39,P62593,0.0656599,NO,132,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.9,-3.795,2.895,,,H,A,0.46,-0.93,8.408,,64.69,PHH,-1.138,0.0495842,0.000962524,0.0656599 kka2_1:1_V80Q,kka2_1:1_80,Kka2,kka2_1:1,P00552,0.0657037,NO,80,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.144,-4.244,3.1,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.520039,0.00488211,0.0657037 kka2_1:4_D220K,kka2_1:4_220,Kka2,kka2_1:4,P00552,0.065809,NO,220,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.787,-3.529,2.742,,,H,A,0.75,-1.14,1.237,,46.59,PAH,-1.152,0.168804,0.00158066,0.065809 kka2_1:8_F206N,kka2_1:8_206,Kka2,kka2_1:8,P00552,0.0660492,NO,206,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.349,-4.18,2.831,,0.006,E,B,1.62,-1.21,1.052,,63.64,OHH,-1.04,0.100394,0.00936868,0.0660492 kka2_1:8_F206N,kka2_1:8_206,Kka2,kka2_1:8,P00552,0.0660492,NO,206,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.349,-4.18,2.831,,0.006,E,B,1.62,-1.21,1.052,,63.64,OHH,-1.04,0.100394,0.00936868,0.0660492 kka2_1:1_R44F,kka2_1:1_44,Kka2,kka2_1:1,P00552,0.0660986,NO,44,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.062,-4.405,2.343,,0.487,S,B,1.2,-0.35,2.717,,71.59,OBO,-1.80767,0.520039,0.00745043,0.0660986 beta-lactamase_2500_F70D,beta-lactamase_2500_70,TEM-1,beta-lactamase_2500,P62593,0.0661314,NO,70,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.169,-3.91,2.741,,,H,A,0.58,-1.34,1.918,,63.99,PHB,-0.980667,0.361275,0.00193499,0.0661314 beta-lactamase_2500_L160W,beta-lactamase_2500_160,TEM-1,beta-lactamase_2500,P62593,0.0663321,NO,160,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.977,-5.194,4.217,,0.022,,B,0.55,-0.6,0.895,,44.41,BHA,-0.936,0.361275,0.00193775,0.0663321 beta-lactamase_2500_N168F,beta-lactamase_2500_168,TEM-1,beta-lactamase_2500,P62593,0.0665089,NO,168,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-1.029,-4.27,3.241,,0.113,G,A,0.61,-0.4,2.9,,44.41,HPA,-1.13233,0.361275,0.00288667,0.0665089 kka2_1:1_G189W,kka2_1:1_189,Kka2,kka2_1:1,P00552,0.0666467,NO,189,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.596,-5.126,4.53,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.520039,0.00253688,0.0666467 beta-lactamase_2500_T158H,beta-lactamase_2500_158,TEM-1,beta-lactamase_2500,P62593,0.066648,NO,158,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.116,-4.689,3.573,,0.036,,B,0.22,-0.85,1.344,,69.58,HPB,-1.269,0.361275,0.00341825,0.066648 kka2_1:4_D227K,kka2_1:4_227,Kka2,kka2_1:4,P00552,0.066823,NO,227,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.758,-3.364,1.606,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.168804,0.00745029,0.066823 beta-lactamase_2500_L150P,beta-lactamase_2500_150,TEM-1,beta-lactamase_2500,P62593,0.0668922,NO,150,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.326,-4.037,2.711,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.361275,0.00463171,0.0668922 kka2_1:2_C77K,kka2_1:2_77,Kka2,kka2_1:2,P00552,0.0668948,NO,77,C,K,CK,Special,PositiveCharge,5.07,9.74,4.67,202,121,146,25,108.5,168.6,60.1,-1.477,-3.834,2.357,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.295029,0.00441216,0.0668948 beta-lactamase_2500_A133R,beta-lactamase_2500_133,TEM-1,beta-lactamase_2500,P62593,0.0669123,NO,133,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.186,-3.865,2.679,,,H,A,0.46,-0.86,2.649,,67.83,HHP,-0.988333,0.361275,0.00468022,0.0669123 beta-lactamase_R81P,beta-lactamase_81,TEM-1,beta-lactamase,P62593,0.0669735,NO,81,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.466,-3.949,2.483,5.12166,0.218,H,A,0.68,1.66,1.236,,50,PBH,-1.60667,0.221079,0.00499763,0.0669735 beta-lactamase_2500_A124W,beta-lactamase_2500_124,TEM-1,beta-lactamase_2500,P62593,0.0670643,NO,124,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.181,-5.322,4.141,,,H,A,0.46,-0.9,0.314,,64.34,HHH,-1.152,0.361275,0.00481399,0.0670643 E1_Ubiquitin_G76I,E1_Ubiquitin_76,Uba1,E1_Ubiquitin,P0CG63,0.0671972,NO,76,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.999,-4.046,3.047,,0.23,,B,0.75,0.08,1.702,,83.73,OOO,-0.999,0.18783,0.00125575,0.0671972 kka2_1:2_L232K,kka2_1:2_232,Kka2,kka2_1:2,P00552,0.0672093,NO,232,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.514,-3.945,2.431,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.295029,0.00800103,0.0672093 beta-lactamase_K232V,beta-lactamase_232,TEM-1,beta-lactamase,P62593,0.0673632,NO,232,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.012,-3.626,2.614,5.18286,,E,B,2.92,-1.1,1.174,,65.03,ABP,-1.238,0.221079,0.00313441,0.0673632 beta-lactamase_625_T179D,beta-lactamase_625_179,TEM-1,beta-lactamase_625,P62593,0.0674743,NO,179,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.085,-3.517,2.432,,,E,B,0.22,-1.38,0.367,,73.08,PPH,-1.557,0.213352,0.00226045,0.0674743 beta-lactamase_625_L167Y,beta-lactamase_625_167,TEM-1,beta-lactamase_625,P62593,0.067498,NO,167,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.138,-4.067,2.929,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.213352,0.00303566,0.067498 beta-lactamase_156_M209H,beta-lactamase_156_209,TEM-1,beta-lactamase_156,P62593,0.0675401,NO,209,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.442,-4.813,3.371,,,H,A,0.55,-0.97,1.066,,64.69,HHA,-1.52633,0.111618,0.00625021,0.0675401 kka2_1:4_D216W,kka2_1:4_216,Kka2,kka2_1:4,P00552,0.0675473,NO,216,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.785,-5.543,4.758,,0.018,E,B,0.75,-0.51,0.112,,19.32,HAB,-0.970333,0.168804,0.00229969,0.0675473 beta-lactamase_2500_D129G,beta-lactamase_2500_129,TEM-1,beta-lactamase_2500,P62593,0.0676397,NO,129,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.816,-3.182,2.366,,,,B,0.75,-0.69,1.29,,34.97,PAP,-0.818,0.361275,0.00109178,0.0676397 kka2_1:4_T187R,kka2_1:4_187,Kka2,kka2_1:4,P00552,0.0677374,NO,187,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.273,-3.94,2.667,,0.007,E,B,0.22,-0.85,2.73,,52.27,HPB,-1.06567,0.168804,0.00693073,0.0677374 kka2_1:4_V75P,kka2_1:4_75,Kka2,kka2_1:4,P00552,0.0679474,NO,75,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-2.06,-4.189,2.129,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.168804,0.00693733,0.0679474 kka2_1:1_V75P,kka2_1:1_75,Kka2,kka2_1:1,P00552,0.0679487,NO,75,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-2.06,-4.189,2.129,,0.042,.,B,0.44,-0.2,2.815,,71.59,OHO,-1.563,0.520039,0.00693733,0.0679487 beta-lactamase_39_G243Y,beta-lactamase_39_243,TEM-1,beta-lactamase_39,P62593,0.0679555,NO,243,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.0495842,0.00464034,0.0679555 beta-lactamase_M209Y,beta-lactamase_209,TEM-1,beta-lactamase,P62593,0.0679837,NO,209,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.442,-3.865,2.423,5.44502,,H,A,1.75,-0.97,1.402,,64.69,HHA,-1.52633,0.221079,0.00625021,0.0679837 beta-lactamase_156_G43E,beta-lactamase_156_43,TEM-1,beta-lactamase_156,P62593,0.0680737,NO,43,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.62,-3.665,3.045,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.111618,0.00120151,0.0680737 kka2_1:2_T187F,kka2_1:2_187,Kka2,kka2_1:2,P00552,0.0682546,NO,187,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.273,-4.193,2.92,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.295029,0.00693073,0.0682546 beta-lactamase_2500_V31R,beta-lactamase_2500_31,TEM-1,beta-lactamase_2500,P62593,0.0683156,NO,31,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.822,-4.173,2.351,,,H,A,0.44,-0.46,0.955,,73.78,BHB,-2.03767,0.361275,0.00478065,0.0683156 beta-lactamase_2500_V31D,beta-lactamase_2500_31,TEM-1,beta-lactamase_2500,P62593,0.0683609,NO,31,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.822,-4.049,2.227,,,H,A,0.44,-0.46,0.955,,73.78,BHB,-2.03767,0.361275,0.00478065,0.0683609 kka2_1:2_M197W,kka2_1:2_197,Kka2,kka2_1:2,P00552,0.0683736,NO,197,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.707,-5.268,3.561,,0.121,E,B,0.55,-1.19,2.097,,65.53,HHH,-1.847,0.295029,0.00921295,0.0683736 beta-lactamase_625_A133H,beta-lactamase_625_133,TEM-1,beta-lactamase_625,P62593,0.0684582,NO,133,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.186,-4.769,3.583,,,H,A,0.46,-0.86,0.373,,67.83,HHP,-0.988333,0.213352,0.00468022,0.0684582 beta-lactamase_2500_C75K,beta-lactamase_2500_75,TEM-1,beta-lactamase_2500,P62593,0.0684949,NO,75,C,K,CK,Special,PositiveCharge,5.07,9.74,4.67,202,121,146,25,108.5,168.6,60.1,-1.245,-3.786,2.541,,,H,A,0.46,-0.87,0.844,,50,HOO,-1.24333,0.361275,0.0034616,0.0684949 beta-lactamase_156_M209E,beta-lactamase_156_209,TEM-1,beta-lactamase_156,P62593,0.068497,NO,209,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.442,-3.84,2.398,,,H,A,0.55,-0.97,1.066,,64.69,HHA,-1.52633,0.111618,0.00625021,0.068497 beta-lactamase_2500_C121K,beta-lactamase_2500_121,TEM-1,beta-lactamase_2500,P62593,0.0685385,NO,121,C,K,CK,Special,PositiveCharge,5.07,9.74,4.67,202,121,146,25,108.5,168.6,60.1,-0.953,-3.72,2.767,,,H,A,0.46,-0.81,1.174,,63.29,HOP,-1.46767,0.361275,0.000744322,0.0685385 beta-lactamase_156_P181E,beta-lactamase_156_181,TEM-1,beta-lactamase_156,P62593,0.0685951,NO,181,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.813,-3.466,2.653,,,H,A,0.52,-1.14,1.078,,61.54,HOH,-1.795,0.111618,0.000703122,0.0685951 beta-lactamase_L247P,beta-lactamase_247,TEM-1,beta-lactamase,P62593,0.0687592,NO,247,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.48,-4.114,2.634,5.28771,0.007,E,B,2.89,-0.72,2.951,,63.99,HHO,-1.79833,0.221079,0.00611275,0.0687592 E1_Ubiquitin_H70R,E1_Ubiquitin_70,Uba1,E1_Ubiquitin,P0CG63,0.0689655,NO,70,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-1.36,,,,0.05,E,B,0.61,-0.97,,,93.18,HBH,-1.146,0.18783,0.00206914,0.0689655 beta-lactamase_2500_L137D,beta-lactamase_2500_137,TEM-1,beta-lactamase_2500,P62593,0.0689898,NO,137,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.03,-4.128,3.098,,,H,A,0.55,-0.38,0.769,,42.31,HHP,-1.58933,0.361275,0.00278599,0.0689898 beta-lactamase_39_S68Y,beta-lactamase_39_68,TEM-1,beta-lactamase_39,P62593,0.0690106,NO,68,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-0.913,-4.188,3.275,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.0495842,0.000800065,0.0690106 beta-lactamase_39_G249P,beta-lactamase_39_249,TEM-1,beta-lactamase_39,P62593,0.0690902,NO,249,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.312,-2.663,1.351,,0.256,S,B,0.23,0.04,30.841,30.841,72.73,HOO,-1.81367,0.0495842,0.00220169,0.0690902 kka2_1:8_R258I,kka2_1:8_258,Kka2,kka2_1:8,P00552,0.0691425,NO,258,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.626,-3.905,2.279,,0.316,H,A,0.16,-0.85,5.58,,53.03,HBH,-1.25933,0.100394,0.00983174,0.0691425 kka2_1:8_R258I,kka2_1:8_258,Kka2,kka2_1:8,P00552,0.0691425,NO,258,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.626,-3.905,2.279,,0.316,H,A,0.16,-0.85,5.58,,53.03,HBH,-1.25933,0.100394,0.00983174,0.0691425 kka2_1:8_R258Y,kka2_1:8_258,Kka2,kka2_1:8,P00552,0.0691425,NO,258,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.626,-4.283,2.657,,0.316,H,A,0.16,-0.85,5.58,,53.03,HBH,-1.25933,0.100394,0.00983174,0.0691425 kka2_1:8_R258Y,kka2_1:8_258,Kka2,kka2_1:8,P00552,0.0691425,NO,258,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.626,-4.283,2.657,,0.316,H,A,0.16,-0.85,5.58,,53.03,HBH,-1.25933,0.100394,0.00983174,0.0691425 beta-lactamase_625_E164S,beta-lactamase_625_164,TEM-1,beta-lactamase_625,P62593,0.0692032,NO,164,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-0.948,-3.21,2.262,,0.011,T,B,1.04,-0.4,1.321,,64.69,HAO,-1.388,0.213352,0.00137286,0.0692032 beta-lactamase_2500_N130T,beta-lactamase_2500_130,TEM-1,beta-lactamase_2500,P62593,0.0692692,NO,130,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-0.798,-3.196,2.398,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.361275,0.000683376,0.0692692 kka2_1:4_L94W,kka2_1:4_94,Kka2,kka2_1:4,P00552,0.0695021,NO,94,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.618,-5.174,3.556,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.168804,0.00520888,0.0695021 beta-lactamase_39_E164F,beta-lactamase_39_164,TEM-1,beta-lactamase_39,P62593,0.0695581,NO,164,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-0.948,-4.341,3.393,,0.011,T,B,1.04,-0.4,0.664,,64.69,HAO,-1.388,0.0495842,0.00137286,0.0695581 beta-lactamase_625_G234N,beta-lactamase_625_234,TEM-1,beta-lactamase_625,P62593,0.0696237,NO,234,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.62,-3.448,2.828,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.213352,0.000889577,0.0696237 kka2_1:4_A78F,kka2_1:4_78,Kka2,kka2_1:4,P00552,0.0696363,NO,78,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.744,-4.44,2.696,,0.078,.,B,0.46,-0.53,0.594,,56.06,OHH,-1.863,0.168804,0.00457299,0.0696363 beta-lactamase_39_V72D,beta-lactamase_39_72,TEM-1,beta-lactamase_39,P62593,0.0696803,NO,72,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.658,-3.942,2.284,,,H,A,0.44,-1.03,1.92,,65.73,BHH,-1.32167,0.0495842,0.00501194,0.0696803 beta-lactamase_39_A132K,beta-lactamase_39_132,TEM-1,beta-lactamase_39,P62593,0.0696955,NO,132,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.9,-3.501,2.601,,,H,A,0.46,-0.93,8.408,,64.69,PHH,-1.138,0.0495842,0.000962524,0.0696955 kka2_1:8_A78Y,kka2_1:8_78,Kka2,kka2_1:8,P00552,0.0697018,NO,78,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.744,-4.391,2.647,,0.078,,B,1.04,-0.53,1.251,,56.06,OHH,-1.863,0.100394,0.00457299,0.0697018 kka2_1:8_A78Y,kka2_1:8_78,Kka2,kka2_1:8,P00552,0.0697018,NO,78,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.744,-4.391,2.647,,0.078,,B,1.04,-0.53,1.251,,56.06,OHH,-1.863,0.100394,0.00457299,0.0697018 kka2_1:2_G205K,kka2_1:2_205,Kka2,kka2_1:2,P00552,0.0699518,NO,205,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.596,-3.71,3.114,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.295029,0.00221855,0.0699518 kka2_1:1_V198P,kka2_1:1_198,Kka2,kka2_1:1,P00552,0.0699684,NO,198,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.719,-3.911,2.192,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.520039,0.00835002,0.0699684 beta-lactamase_156_K71V,beta-lactamase_156_71,TEM-1,beta-lactamase_156,P62593,0.0701164,NO,71,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-0.8,-3.529,2.729,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.111618,0.00103192,0.0701164 kka2_1:2_A229L,kka2_1:2_229,Kka2,kka2_1:2,P00552,0.070124,NO,229,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.739,-3.501,1.762,,0.32,H,A,0.46,-0.7,6.549,,63.64,HHA,-1.851,0.295029,0.00942138,0.070124 beta-lactamase_G279D,beta-lactamase_279,TEM-1,beta-lactamase,P62593,0.0701555,NO,279,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.038,-3.523,2.485,4.53882,,H,A,0.46,-0.97,3.066,,62.59,HOH,-1.36467,0.221079,0.0192826,0.0701555 beta-lactamase_G279K,beta-lactamase_279,TEM-1,beta-lactamase,P62593,0.0701555,NO,279,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.038,-3.605,2.567,4.53882,,H,A,0.46,-0.97,3.066,,62.59,HOH,-1.36467,0.221079,0.0192826,0.0701555 beta-lactamase_156_R162I,beta-lactamase_156_162,TEM-1,beta-lactamase_156,P62593,0.0701602,NO,162,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.016,-3.867,2.851,,0.124,S,B,1.2,-0.37,7.444,,64.69,ABH,-1.25,0.111618,0.000561334,0.0701602 kka2_1:4_F206N,kka2_1:4_206,Kka2,kka2_1:4,P00552,0.070174,NO,206,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.349,-4.18,2.831,,0.006,E,B,0.58,-1.21,1.342,,63.64,OHH,-1.04,0.168804,0.00936868,0.070174 kka2_1:2_Q219N,kka2_1:2_219,Kka2,kka2_1:2,P00552,0.0702084,NO,219,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-0.93,-3.499,2.569,,0.088,H,A,0.4,-0.85,1.917,,50,HPA,-1.05167,0.295029,0.00237913,0.0702084 beta-lactamase_0_V117I,beta-lactamase_0_117,TEM-1,beta-lactamase_0,P62593,0.0702555,NO,117,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.53,-1.923,0.393,,,H,A,0.44,-0.34,1.16,,65.03,PHB,-1.741,0.0500837,0.00467906,0.0702555 beta-lactamase_2500_I245Q,beta-lactamase_2500_245,TEM-1,beta-lactamase_2500,P62593,0.0702589,NO,245,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.361275,0.00391032,0.0702589 WW_domain_G185V,WW_domain_185,Yap65,WW_domain,P46937,0.0703126,NO,185,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.861,-3.531,2.67,6.22337,,,,,,,,,POP,-1.194,0.153962,0.00199178,0.0703126 beta-lactamase_2500_K232G,beta-lactamase_2500_232,TEM-1,beta-lactamase_2500,P62593,0.0703948,NO,232,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.012,-3.401,2.389,,,E,B,2.34,-1.1,3.048,,65.03,ABP,-1.238,0.361275,0.00313441,0.0703948 PSD95pdz3_G329P,PSD95pdz3_329,PSD95pdz3,PSD95pdz3,P31016,0.0706047,NO,329,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.008,-3.561,2.553,4.7671,,,,,19.7075,,,,HOO,-1.16033,0.0758425,0.000974577,0.0706047 kka2_1:2_V198D,kka2_1:2_198,Kka2,kka2_1:2,P00552,0.0706259,NO,198,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.719,-3.799,2.08,,0.05,E,B,1.48,-0.95,1.074,,56.06,HHA,-1.88667,0.295029,0.00835002,0.0706259 beta-lactamase_39_F64G,beta-lactamase_39_64,TEM-1,beta-lactamase_39,P62593,0.0707114,NO,64,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-0.841,-3.583,2.742,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.0495842,0.000947691,0.0707114 kka2_1:1_L241G,kka2_1:1_241,Kka2,kka2_1:1,P00552,0.0707928,NO,241,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.158,-3.805,2.647,,0.08,H,A,0.55,-0.82,1.685,,63.26,HHH,-1.58533,0.520039,0.0117299,0.0707928 kka2_1:8_V49Y,kka2_1:8_49,Kka2,kka2_1:8,P00552,0.0708175,NO,49,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.614,-4.126,2.512,,,E,B,1.48,-0.77,1.31,,64.39,HHB,-1.3,0.100394,0.00615685,0.0708175 kka2_1:8_V49Y,kka2_1:8_49,Kka2,kka2_1:8,P00552,0.0708175,NO,49,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.614,-4.126,2.512,,,E,B,1.48,-0.77,1.31,,64.39,HHB,-1.3,0.100394,0.00615685,0.0708175 beta-lactamase_2500_L79P,beta-lactamase_2500_79,TEM-1,beta-lactamase_2500,P62593,0.0708373,NO,79,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.842,-4.102,3.26,,0.007,H,A,0.55,-0.16,0.823,,50.35,HHP,-1.44333,0.361275,0.000947397,0.0708373 beta-lactamase_39_I280K,beta-lactamase_39_280,TEM-1,beta-lactamase_39,P62593,0.0709541,NO,280,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.0495842,0.0530888,0.0709541 kka2_1:2_C209N,kka2_1:2_209,Kka2,kka2_1:2,P00552,0.0710331,NO,209,C,N,CN,Special,Polar,5.07,5.47157,0.401575,139,121,132,11,108.5,114.1,5.6,-0.906,-4.174,3.268,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.295029,0.00260862,0.0710331 beta-lactamase_625_S128F,beta-lactamase_625_128,TEM-1,beta-lactamase_625,P62593,0.0710934,NO,128,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-0.84,-4.067,3.227,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.213352,0.00071483,0.0710934 beta-lactamase_2500_W227V,beta-lactamase_2500_227,TEM-1,beta-lactamase_2500,P62593,0.0711686,NO,227,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-0.982,-3.747,2.765,,0.272,,B,0.47,-0.29,1.37,,74.48,OHH,-1.595,0.361275,0.00226019,0.0711686 kka2_1:1_G74R,kka2_1:1_74,Kka2,kka2_1:1,P00552,0.0712598,NO,74,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.18,-3.943,2.763,,0.621,T,l,0.75,0.2,15.356,15.356,64.39,POH,-1.91667,0.520039,0.00587035,0.0712598 beta-lactamase_P181H,beta-lactamase_181,TEM-1,beta-lactamase,P62593,0.0712619,NO,181,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.813,-4.706,3.893,5.14752,,H,A,1.1,-1.14,1.357,,61.54,HOH,-1.795,0.221079,0.000703122,0.0712619 hsp90_W585E,hsp90_585,hsp90,hsp90,P02829,0.0712725,NO,585,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-4.251,-2.818,0,5.31455,0.508,,B,1.22,0.43,,,,OHP,-3.17533,0.368192,0.000222939,0.0712725 PSD95pdz3_I327R,PSD95pdz3_327,PSD95pdz3,PSD95pdz3,P31016,0.0712901,NO,327,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.63,-3.84,2.21,5.7413,,,,,14.0388,,,,PHH,-1.50167,0.0758425,0.000998774,0.0712901 kka2_1:8_L94N,kka2_1:8_94,Kka2,kka2_1:8,P00552,0.0713739,NO,94,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.618,-4.108,2.49,,0.058,E,B,1.59,-0.52,2.197,,56.06,HHO,-1.612,0.100394,0.00520888,0.0713739 kka2_1:8_L94N,kka2_1:8_94,Kka2,kka2_1:8,P00552,0.0713739,NO,94,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.618,-4.108,2.49,,0.058,E,B,1.59,-0.52,2.197,,56.06,HHO,-1.612,0.100394,0.00520888,0.0713739 beta-lactamase_2500_V31P,beta-lactamase_2500_31,TEM-1,beta-lactamase_2500,P62593,0.0714864,NO,31,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.822,-4.128,2.306,,,H,A,0.44,-0.46,0.955,,73.78,BHB,-2.03767,0.361275,0.00478065,0.0714864 kka2_1:2_Q100W,kka2_1:2_100,Kka2,kka2_1:2,P00552,0.0714948,NO,100,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.77,-5.568,2.798,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.295029,0.0066405,0.0714948 beta-lactamase_W227E,beta-lactamase_227,TEM-1,beta-lactamase,P62593,0.0716034,NO,227,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-0.982,-3.914,2.932,4.86393,0.272,,B,0.99,-0.29,1.37,,74.48,OHH,-1.595,0.221079,0.00226019,0.0716034 beta-lactamase_625_K232D,beta-lactamase_625_232,TEM-1,beta-lactamase_625,P62593,0.0716543,NO,232,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.012,-3.566,2.554,,,E,B,2.34,-1.1,1.992,,65.03,ABP,-1.238,0.213352,0.00313441,0.0716543 beta-lactamase_625_R242D,beta-lactamase_625_242,TEM-1,beta-lactamase_625,P62593,0.0716679,NO,242,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.213352,0.00452879,0.0716679 kka2_1:1_A172Y,kka2_1:1_172,Kka2,kka2_1:1,P00552,0.07172,NO,172,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.757,-4.449,2.692,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.520039,0.0079265,0.07172 kka2_1:2_Y257K,kka2_1:2_257,Kka2,kka2_1:2,P00552,0.071774,NO,257,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-1.064,-3.837,2.773,,0.022,H,A,0.21,-0.88,0.833,,52.65,HHB,-1.39333,0.295029,0.0148191,0.071774 beta-lactamase_I125D,beta-lactamase_125,TEM-1,beta-lactamase,P62593,0.0719325,NO,125,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.441,-3.998,2.557,5.23481,,H,A,2.82,-0.7,2.301,,63.29,HHP,-1.248,0.221079,0.00383964,0.0719325 beta-lactamase_L79D,beta-lactamase_79,TEM-1,beta-lactamase,P62593,0.0719325,NO,79,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.842,-4.141,3.299,4.98681,0.007,H,A,1.07,-0.16,0.823,,50.35,HHP,-1.44333,0.221079,0.000947397,0.0719325 kka2_1:2_D190F,kka2_1:2_190,Kka2,kka2_1:2,P00552,0.0719633,NO,190,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.708,-4.32,3.612,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.295029,0.00247989,0.0719633 beta-lactamase_625_L136Q,beta-lactamase_625_136,TEM-1,beta-lactamase_625,P62593,0.0721458,NO,136,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.232,-4.242,3.01,,,H,A,0.55,-0.34,0.336,,48.95,HHH,-1.088,0.213352,0.00442304,0.0721458 beta-lactamase_G239I,beta-lactamase_239,TEM-1,beta-lactamase,P62593,0.0721603,NO,239,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.819,-4.139,3.32,4.85529,0.115,T,l,0.77,-0.62,1.817,,42.31,BOP,-1.45267,0.221079,0.00213852,0.0721603 beta-lactamase_625_A185H,beta-lactamase_625_185,TEM-1,beta-lactamase_625,P62593,0.0722089,NO,185,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.406,-4.889,3.483,,,H,A,0.46,-1.02,0.365,,65.03,HHP,-1.84033,0.213352,0.00467449,0.0722089 kka2_1:2_F240W,kka2_1:2_240,Kka2,kka2_1:2,P00552,0.0722163,NO,240,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-0.911,-4.558,3.647,,,H,A,0.58,-1.21,0.373,,50.38,BHH,-1.67267,0.295029,0.00552543,0.0722163 kka2_1:1_G213I,kka2_1:1_213,Kka2,kka2_1:1,P00552,0.072367,NO,213,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.596,-4.264,3.668,,,E,b,0.29,-0.4,,,,HOH,-0.920333,0.520039,0.00187654,0.072367 PSD95pdz3_F325E,PSD95pdz3_325,PSD95pdz3,PSD95pdz3,P31016,0.0724118,NO,325,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.524,-3.572,2.048,5.50654,,,,,12.7236,,,,OHP,-1.314,0.0758425,0.00102273,0.0724118 beta-lactamase_L74H,beta-lactamase_74,TEM-1,beta-lactamase,P62593,0.072455,NO,74,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.296,-4.896,3.6,5.50288,,H,A,1.75,-0.91,1.581,,50,HHO,-1.34933,0.221079,0.00493255,0.072455 kka2_1:4_V80E,kka2_1:4_80,Kka2,kka2_1:4,P00552,0.0725928,NO,80,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.144,-3.785,2.641,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.168804,0.00488211,0.0725928 beta-lactamase_625_I261K,beta-lactamase_625_261,TEM-1,beta-lactamase_625,P62593,0.0726004,NO,261,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.213352,0.0123091,0.0726004 kka2_1:2_A78H,kka2_1:2_78,Kka2,kka2_1:2,P00552,0.0726978,NO,78,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.744,-4.753,3.009,,0.078,.,B,0.46,-0.53,0.206,,56.06,OHH,-1.863,0.295029,0.00457299,0.0726978 beta-lactamase_2500_D155R,beta-lactamase_2500_155,TEM-1,beta-lactamase_2500,P62593,0.0727255,NO,155,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.889,-3.873,2.984,,0.049,,B,0.75,-0.9,2.386,,64.69,OAB,-1.62267,0.361275,0.00135315,0.0727255 kka2_1:8_C209N,kka2_1:8_209,Kka2,kka2_1:8,P00552,0.0727609,NO,209,C,N,CN,Special,Polar,5.07,5.47157,0.401575,139,121,132,11,108.5,114.1,5.6,-0.906,-4.174,3.268,,,,a,1.5,-0.89,0.391,,19.32,AOO,-0.903,0.100394,0.00260862,0.0727609 kka2_1:8_C209N,kka2_1:8_209,Kka2,kka2_1:8,P00552,0.0727609,NO,209,C,N,CN,Special,Polar,5.07,5.47157,0.401575,139,121,132,11,108.5,114.1,5.6,-0.906,-4.174,3.268,,,,a,1.5,-0.89,0.391,,19.32,AOO,-0.903,0.100394,0.00260862,0.0727609 beta-lactamase_2500_E164P,beta-lactamase_2500_164,TEM-1,beta-lactamase_2500,P62593,0.0727684,NO,164,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-0.948,-3.725,2.777,,0.011,T,B,1.04,-0.4,0.352,,64.69,HAO,-1.388,0.361275,0.00137286,0.0727684 kka2_1:4_L223S,kka2_1:4_223,Kka2,kka2_1:4,P00552,0.0727828,NO,223,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.861,-3.684,2.823,,,H,A,1.59,-1.24,1.268,,50,HHH,-0.854333,0.168804,0.00253574,0.0727828 beta-lactamase_156_G243D,beta-lactamase_156_243,TEM-1,beta-lactamase_156,P62593,0.0728639,NO,243,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.532,,,,,E,B,0.77,-1.24,2.866,,50,BOH,-1.46867,0.111618,0.00464034,0.0728639 kka2_1:2_G95W,kka2_1:2_95,Kka2,kka2_1:2,P00552,0.073141,NO,95,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-2.403,-5.488,3.085,,0.126,E,B,0.29,-0.74,0.359,,71.59,HOA,-2.198,0.295029,0.00743616,0.073141 beta-lactamase_2500_T179E,beta-lactamase_2500_179,TEM-1,beta-lactamase_2500,P62593,0.0732062,NO,179,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.085,-3.446,2.361,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.361275,0.00226045,0.0732062 beta-lactamase_2500_A185Y,beta-lactamase_2500_185,TEM-1,beta-lactamase_2500,P62593,0.073242,NO,185,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.406,-4.227,2.821,,,H,A,0.46,-1.02,2.999,,65.03,HHP,-1.84033,0.361275,0.00467449,0.073242 kka2_1:8_L232S,kka2_1:8_232,Kka2,kka2_1:8,P00552,0.0733141,NO,232,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.514,-3.04,1.526,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.100394,0.00800103,0.0733141 kka2_1:8_L232S,kka2_1:8_232,Kka2,kka2_1:8,P00552,0.0733141,NO,232,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.514,-3.04,1.526,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.100394,0.00800103,0.0733141 PSD95pdz3_I359R,PSD95pdz3_359,PSD95pdz3,PSD95pdz3,P31016,0.0734089,NO,359,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.63,-3.84,2.21,5.35151,,,,,14.8012,,,,PHH,-1.58667,0.0758425,0.000580694,0.0734089 beta-lactamase_C75P,beta-lactamase_75,TEM-1,beta-lactamase,P62593,0.0734132,NO,75,C,P,CP,Special,Special,5.07,6.3,1.23,169,121,115,-6,108.5,112.7,4.2,-1.245,-4.012,2.767,4.88171,,H,A,0.25,-0.87,0.876,,50,HOO,-1.24333,0.221079,0.0034616,0.0734132 beta-lactamase_D161P,beta-lactamase_161,TEM-1,beta-lactamase,P62593,0.0734132,NO,161,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.891,-3.704,2.813,5.12208,0.341,,A,0.23,-0.52,1.602,,61.19,HAB,-0.961333,0.221079,0.000897697,0.0734132 beta-lactamase_M209E,beta-lactamase_209,TEM-1,beta-lactamase,P62593,0.0734132,NO,209,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.442,-3.84,2.398,5.44502,,H,A,1.75,-0.97,1.402,,64.69,HHA,-1.52633,0.221079,0.00625021,0.0734132 kka2_1:1_A172M,kka2_1:1_172,Kka2,kka2_1:1,P00552,0.0734802,NO,172,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.757,-4.761,3.004,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.520039,0.0079265,0.0734802 beta-lactamase_D129N,beta-lactamase_129,TEM-1,beta-lactamase,P62593,0.0735812,NO,129,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.816,-3.272,2.456,4.84204,,,B,1.33,-0.69,0.548,,34.97,PAP,-0.818,0.221079,0.00109178,0.0735812 beta-lactamase_R255D,beta-lactamase_255,TEM-1,beta-lactamase,P62593,0.073792,NO,255,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.266,-4.065,1.799,5.55882,0.141,E,B,0.68,0.38,1.199,,63.99,PBH,-2.00433,0.221079,0.00499612,0.073792 beta-lactamase_2500_D129S,beta-lactamase_2500_129,TEM-1,beta-lactamase_2500,P62593,0.0738118,NO,129,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.816,-3.186,2.37,,,,B,0.75,-0.69,1.29,,34.97,PAP,-0.818,0.361275,0.00109178,0.0738118 beta-lactamase_L188K,beta-lactamase_188,TEM-1,beta-lactamase,P62593,0.0738535,NO,188,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.166,-3.695,2.529,5.55434,,H,A,1.07,-0.3,1.574,,60.14,PHB,-1.47033,0.221079,0.00295687,0.0738535 kka2_1:2_E230I,kka2_1:2_230,Kka2,kka2_1:2,P00552,0.0738723,NO,230,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.672,-3.969,1.297,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.295029,0.00920051,0.0738723 beta-lactamase_2500_A185P,beta-lactamase_2500_185,TEM-1,beta-lactamase_2500,P62593,0.0739357,NO,185,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.406,-2.861,1.455,,,H,A,0.46,-1.02,2.999,,65.03,HHP,-1.84033,0.361275,0.00467449,0.0739357 beta-lactamase_2500_L79E,beta-lactamase_2500_79,TEM-1,beta-lactamase_2500,P62593,0.0739494,NO,79,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.842,-3.887,3.045,,0.007,H,A,0.55,-0.16,0.823,,50.35,HHP,-1.44333,0.361275,0.000947397,0.0739494 kka2_1:2_G213W,kka2_1:2_213,Kka2,kka2_1:2,P00552,0.0741066,NO,213,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.596,-5.126,4.53,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.295029,0.00187654,0.0741066 kka2_1:4_C192W,kka2_1:4_192,Kka2,kka2_1:4,P00552,0.0741857,NO,192,C,W,CW,Special,Hydrophobic,5.07,5.89,0.82,215,121,204,83,108.5,227.8,119.3,-1.067,-5.111,4.044,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.168804,0.00485428,0.0741857 kka2_1:2_G213H,kka2_1:2_213,Kka2,kka2_1:2,P00552,0.0741905,NO,213,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.596,-4.708,4.112,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.295029,0.00187654,0.0741905 beta-lactamase_625_A132F,beta-lactamase_625_132,TEM-1,beta-lactamase_625,P62593,0.0742138,NO,132,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.9,-4.091,3.191,,,H,A,0.46,-0.93,0.316,,64.69,PHH,-1.138,0.213352,0.000962524,0.0742138 beta-lactamase_625_A246D,beta-lactamase_625_246,TEM-1,beta-lactamase_625,P62593,0.0746578,NO,246,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.121,-4.086,1.965,,0.01,E,B,0.46,-1.01,1.201,,73.78,HHH,-1.55633,0.213352,0.00569458,0.0746578 beta-lactamase_156_L248K,beta-lactamase_156_248,TEM-1,beta-lactamase_156,P62593,0.074686,NO,248,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.111618,0.00428493,0.074686 beta-lactamase_39_G243F,beta-lactamase_39_243,TEM-1,beta-lactamase_39,P62593,0.0747212,NO,243,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.0495842,0.00464034,0.0747212 beta-lactamase_2500_K232P,beta-lactamase_2500_232,TEM-1,beta-lactamase_2500,P62593,0.0747535,NO,232,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.012,-3.752,2.74,,,E,B,2.34,-1.1,3.048,,65.03,ABP,-1.238,0.361275,0.00313441,0.0747535 beta-lactamase_2500_N134K,beta-lactamase_2500_134,TEM-1,beta-lactamase_2500,P62593,0.0747557,NO,134,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-0.879,-2.445,1.566,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.361275,0.000644786,0.0747557 beta-lactamase_2500_L74R,beta-lactamase_2500_74,TEM-1,beta-lactamase_2500,P62593,0.0747674,NO,74,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.296,-3.939,2.643,,,H,A,0.55,-0.91,0.746,,50,HHO,-1.34933,0.361275,0.00493255,0.0747674 kka2_1:2_V185W,kka2_1:2_185,Kka2,kka2_1:2,P00552,0.0749149,NO,185,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.045,-5.383,4.338,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.295029,0.00367031,0.0749149 kka2_1:1_C77K,kka2_1:1_77,Kka2,kka2_1:1,P00552,0.0749681,NO,77,C,K,CK,Special,PositiveCharge,5.07,9.74,4.67,202,121,146,25,108.5,168.6,60.1,-1.477,-3.834,2.357,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.520039,0.00441216,0.0749681 PSD95pdz3_L323D,PSD95pdz3_323,PSD95pdz3,PSD95pdz3,P31016,0.0750291,NO,323,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.347,-3.825,2.478,5.12397,,,,,13.8825,,,,OHO,-1.121,0.0758425,0.00104644,0.0750291 kka2_1:2_A229D,kka2_1:2_229,Kka2,kka2_1:2,P00552,0.0751736,NO,229,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.739,-3.667,1.928,,0.32,H,A,0.46,-0.7,6.549,,63.64,HHA,-1.851,0.295029,0.00942138,0.0751736 beta-lactamase_2500_A132R,beta-lactamase_2500_132,TEM-1,beta-lactamase_2500,P62593,0.0752639,NO,132,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.9,-3.795,2.895,,,H,A,0.46,-0.93,8.408,,64.69,PHH,-1.138,0.361275,0.000962524,0.0752639 beta-lactamase_625_E164F,beta-lactamase_625_164,TEM-1,beta-lactamase_625,P62593,0.0752781,NO,164,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-0.948,-4.341,3.393,,0.011,T,B,1.04,-0.4,1.321,,64.69,HAO,-1.388,0.213352,0.00137286,0.0752781 kka2_1:4_M197Y,kka2_1:4_197,Kka2,kka2_1:4,P00552,0.0754133,NO,197,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.707,-4.145,2.438,,0.121,E,B,0.55,-1.19,0.415,,65.53,HHH,-1.847,0.168804,0.00921295,0.0754133 beta-lactamase_625_K71M,beta-lactamase_625_71,TEM-1,beta-lactamase_625,P62593,0.0754835,NO,71,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-0.8,-4.48,3.68,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.213352,0.00103192,0.0754835 beta-lactamase_625_V78P,beta-lactamase_625_78,TEM-1,beta-lactamase_625,P62593,0.0755119,NO,78,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.459,-4.126,2.667,,,H,A,0.44,-0.47,2.045,,63.64,HHH,-1.17833,0.213352,0.00492501,0.0755119 kka2_1:8_L170N,kka2_1:8_170,Kka2,kka2_1:8,P00552,0.0755175,NO,170,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.28,-4.225,2.945,,0.029,H,A,1.59,0.11,1.453,,62.5,AHH,-1.534,0.100394,0.00730791,0.0755175 kka2_1:8_L170N,kka2_1:8_170,Kka2,kka2_1:8,P00552,0.0755175,NO,170,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.28,-4.225,2.945,,0.029,H,A,1.59,0.11,1.453,,62.5,AHH,-1.534,0.100394,0.00730791,0.0755175 beta-lactamase_2500_K71L,beta-lactamase_2500_71,TEM-1,beta-lactamase_2500,P62593,0.0755513,NO,71,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-0.8,-3.358,2.558,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.361275,0.00103192,0.0755513 beta-lactamase_A185N,beta-lactamase_185,TEM-1,beta-lactamase,P62593,0.0757402,NO,185,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.406,-4.005,2.599,4.89877,,H,A,2.34,-1.02,2.999,,65.03,HHP,-1.84033,0.221079,0.00467449,0.0757402 beta-lactamase_F64E,beta-lactamase_64,TEM-1,beta-lactamase,P62593,0.0757402,NO,64,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-0.841,-3.89,3.049,5.70769,0.006,E,B,1.33,-0.95,,,,BHO,-0.892667,0.221079,0.000947691,0.0757402 beta-lactamase_L205H,beta-lactamase_205,TEM-1,beta-lactamase,P62593,0.0757402,NO,205,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.922,-4.828,3.906,5.67023,,H,A,1.3,-0.46,0.678,,42.31,PHH,-1.57767,0.221079,0.00255802,0.0757402 beta-lactamase_2500_K71P,beta-lactamase_2500_71,TEM-1,beta-lactamase_2500,P62593,0.0757969,NO,71,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-0.8,-3.655,2.855,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.361275,0.00103192,0.0757969 beta-lactamase_625_A185F,beta-lactamase_625_185,TEM-1,beta-lactamase_625,P62593,0.0758234,NO,185,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.406,-4.091,2.685,,,H,A,0.46,-1.02,0.365,,65.03,HHP,-1.84033,0.213352,0.00467449,0.0758234 kka2_1:2_F203I,kka2_1:2_203,Kka2,kka2_1:2,P00552,0.0758359,NO,203,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-0.911,-3.319,2.408,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.295029,0.00318738,0.0758359 kka2_1:2_M148Y,kka2_1:2_148,Kka2,kka2_1:2,P00552,0.0758362,NO,148,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.847,-4.225,2.378,,0.268,H,A,1.59,0.71,1.439,,64.39,BHA,-1.65467,0.295029,0.00982664,0.0758362 Pab1_F173D,Pab1_173,Pab1,Pab1,P04147,0.0761388,NO,173,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.477,-3.807,2.33,,,E,B,0.87,-0.16,1.636,,63.26,BHA,-1.36967,0.175299,0.00148779,0.0761388 kka2_1:4_E59R,kka2_1:4_59,Kka2,kka2_1:4,P00552,0.0762773,NO,59,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-0.952,-3.602,2.65,,0.187,.,L,1.04,0.62,3.408,,50.38,PAH,-1.53,0.168804,0.00280355,0.0762773 kka2_1:1_E111N,kka2_1:1_111,Kka2,kka2_1:1,P00552,0.0763159,NO,111,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.28,-3.19,0.91,,0.155,H,A,1.52,-1.14,15.716,15.716,65.53,HAB,-2.27833,0.520039,0.00746789,0.0763159 kka2_1:8_T73D,kka2_1:8_73,Kka2,kka2_1:8,P00552,0.0763399,NO,73,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.51,-3.789,1.279,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.100394,0.00628605,0.0763399 kka2_1:8_T73D,kka2_1:8_73,Kka2,kka2_1:8,P00552,0.0763399,NO,73,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.51,-3.789,1.279,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.100394,0.00628605,0.0763399 kka2_1:1_P12W,kka2_1:1_12,Kka2,kka2_1:1,P00552,0.0763418,NO,12,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.853,-5.545,4.692,,,.,B,0.52,1.25,0.261,,48.11,POH,-1.80767,0.520039,0.00500011,0.0763418 beta-lactamase_E56P,beta-lactamase_56,TEM-1,beta-lactamase,P62593,0.0763748,NO,56,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.043,-3.731,1.688,5.65281,0.198,E,B,0.52,0.31,2.022,,72.73,HAP,-1.94033,0.221079,0.00238534,0.0763748 kka2_1:1_P76A,kka2_1:1_76,Kka2,kka2_1:1,P00552,0.0763793,NO,76,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.449,-1.98,0.531,,0.331,.,B,0.52,-0.41,0.345,,63.64,HOO,-1.662,0.520039,0.00625685,0.0763793 kka2_1:2_R253F,kka2_1:2_253,Kka2,kka2_1:2,P00552,0.0763797,NO,253,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.356,-4.389,3.033,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.295029,0.0144195,0.0763797 beta-lactamase_625_G234P,beta-lactamase_625_234,TEM-1,beta-lactamase_625,P62593,0.0763939,NO,234,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.62,-3.88,3.26,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.213352,0.000889577,0.0763939 beta-lactamase_625_F228P,beta-lactamase_625_228,TEM-1,beta-lactamase_625,P62593,0.0766103,NO,228,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-2.342,-3.088,0.746,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.213352,0.0046669,0.0766103 beta-lactamase_625_E164N,beta-lactamase_625_164,TEM-1,beta-lactamase_625,P62593,0.0767494,NO,164,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-0.948,-3.497,2.549,,0.011,T,B,1.04,-0.4,1.321,,64.69,HAO,-1.388,0.213352,0.00137286,0.0767494 kka2_1:2_Y218P,kka2_1:2_218,Kka2,kka2_1:2,P00552,0.076751,NO,218,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-1.438,-4.207,2.769,,0.122,H,A,0.21,-0.69,1.022,,56.06,BHP,-1.17533,0.295029,0.0126098,0.076751 beta-lactamase_625_A246E,beta-lactamase_625_246,TEM-1,beta-lactamase_625,P62593,0.076778,NO,246,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.121,-3.906,1.785,,0.01,E,B,0.46,-1.01,1.201,,73.78,HHH,-1.55633,0.213352,0.00569458,0.076778 kka2_1:1_R173K,kka2_1:1_173,Kka2,kka2_1:1,P00552,0.0768534,NO,173,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.407,-2.916,0.509,,0.308,H,A,0.16,-0.13,14.756,14.756,65.53,HBH,-1.70533,0.520039,0.00784999,0.0768534 WW_domain_P202S,WW_domain_202,Yap65,WW_domain,P46937,0.0768728,NO,202,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.4,-2.184,0.784,5.64207,,,,,,17.28,17.28,78.57,AOB,-1.436,0.153962,0.00212903,0.0768728 beta-lactamase_625_A133Q,beta-lactamase_625_133,TEM-1,beta-lactamase_625,P62593,0.0768986,NO,133,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.186,-4.056,2.87,,,H,A,0.46,-0.86,0.373,,67.83,HHP,-0.988333,0.213352,0.00468022,0.0768986 kka2_1:1_M197N,kka2_1:1_197,Kka2,kka2_1:1,P00552,0.0769915,NO,197,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.707,-4.155,2.448,,0.121,E,B,1.59,-1.19,2.097,,65.53,HHH,-1.847,0.520039,0.00921295,0.0769915 beta-lactamase_2500_G249M,beta-lactamase_2500_249,TEM-1,beta-lactamase_2500,P62593,0.0770285,NO,249,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.312,,,,0.256,S,B,0.23,0.04,30.841,30.841,72.73,HOO,-1.81367,0.361275,0.00220169,0.0770285 beta-lactamase_F149P,beta-lactamase_149,TEM-1,beta-lactamase,P62593,0.0770914,NO,149,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.299,-4.282,2.983,5.54789,0.195,H,A,1.1,0.11,1.863,,63.99,HHH,-1.46067,0.221079,0.00418462,0.0770914 beta-lactamase_39_A124Y,beta-lactamase_39_124,TEM-1,beta-lactamase_39,P62593,0.0772082,NO,124,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.181,-4.228,3.047,,,H,A,0.46,-0.9,1.367,,64.34,HHH,-1.152,0.0495842,0.00481399,0.0772082 beta-lactamase_625_G236K,beta-lactamase_625_236,TEM-1,beta-lactamase_625,P62593,0.0772584,NO,236,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.784,-3.651,2.867,,0.241,,b,0.29,-0.59,3.506,,64.69,HOO,-1.025,0.213352,0.00162372,0.0772584 beta-lactamase_2500_R242Y,beta-lactamase_2500_242,TEM-1,beta-lactamase_2500,P62593,0.0772645,NO,242,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.361275,0.00452879,0.0772645 kka2_1:4_R226F,kka2_1:4_226,Kka2,kka2_1:4,P00552,0.077266,NO,226,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.392,-4.163,2.771,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.168804,0.0108032,0.077266 beta-lactamase_625_A215D,beta-lactamase_625_215,TEM-1,beta-lactamase_625,P62593,0.0772871,NO,215,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.503,-3.621,2.118,,,,a,0.46,-0.93,3.583,,74.48,HHO,-1.42633,0.213352,0.00544007,0.0772871 kka2_1:2_P76I,kka2_1:2_76,Kka2,kka2_1:2,P00552,0.0773566,NO,76,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.449,-3.871,2.422,,0.331,.,B,0.52,-0.41,0.345,,63.64,HOO,-1.662,0.295029,0.00625685,0.0773566 beta-lactamase_625_S128Q,beta-lactamase_625_128,TEM-1,beta-lactamase_625,P62593,0.0773722,NO,128,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-0.84,-3.674,2.834,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.213352,0.00071483,0.0773722 kka2_1:1_P76V,kka2_1:1_76,Kka2,kka2_1:1,P00552,0.0773996,NO,76,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.449,-2.929,1.48,,0.331,.,B,0.52,-0.41,0.345,,63.64,HOO,-1.662,0.520039,0.00625685,0.0773996 beta-lactamase_V31K,beta-lactamase_31,TEM-1,beta-lactamase,P62593,0.0774854,NO,31,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.822,-3.873,2.051,5.43781,,H,A,2.78,-0.46,2.885,,73.78,BHB,-2.03767,0.221079,0.00478065,0.0774854 beta-lactamase_W227Q,beta-lactamase_227,TEM-1,beta-lactamase,P62593,0.0774854,NO,227,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-0.982,-4.194,3.212,4.86393,0.272,,B,0.99,-0.29,1.37,,74.48,OHH,-1.595,0.221079,0.00226019,0.0774854 beta-lactamase_156_V31K,beta-lactamase_156_31,TEM-1,beta-lactamase_156,P62593,0.0775514,NO,31,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.822,-3.873,2.051,,,H,A,0.44,-0.46,4.126,,73.78,BHB,-2.03767,0.111618,0.00478065,0.0775514 beta-lactamase_2500_I125Y,beta-lactamase_2500_125,TEM-1,beta-lactamase_2500,P62593,0.0776311,NO,125,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.441,-4.111,2.67,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.361275,0.00383964,0.0776311 beta-lactamase_A185Q,beta-lactamase_185,TEM-1,beta-lactamase,P62593,0.0777348,NO,185,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.406,-4.108,2.702,4.89877,,H,A,2.34,-1.02,2.999,,65.03,HHP,-1.84033,0.221079,0.00467449,0.0777348 kka2_1:2_F48M,kka2_1:2_48,Kka2,kka2_1:2,P00552,0.077776,NO,48,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.453,-4.369,2.916,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.295029,0.00475422,0.077776 beta-lactamase_I275N,beta-lactamase_275,TEM-1,beta-lactamase,P62593,0.0777834,NO,275,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.397,-4.128,2.731,5.3999,0.015,H,A,1,-0.52,0.836,,62.59,PHH,-1.541,0.221079,0.0141984,0.0777834 kka2_1:1_G213S,kka2_1:1_213,Kka2,kka2_1:1,P00552,0.0778342,NO,213,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.596,-3.189,2.593,,,E,b,0.29,-0.4,,,,HOH,-0.920333,0.520039,0.00187654,0.0778342 beta-lactamase_2500_T107R,beta-lactamase_2500_107,TEM-1,beta-lactamase_2500,P62593,0.0779515,NO,107,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.117,-3.76,2.643,,,G,A,0.22,-0.06,2.686,,67.83,HPA,-1.265,0.361275,0.00239347,0.0779515 kka2_1:2_Q136P,kka2_1:2_136,Kka2,kka2_1:2,P00552,0.0781721,NO,136,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-3.021,-2.734,-0.287,,0.331,,b,0.4,0.96,2.726,,92.05,BPH,-2.16933,0.295029,0.00624149,0.0781721 beta-lactamase_39_F58P,beta-lactamase_39_58,TEM-1,beta-lactamase_39,P62593,0.0781844,NO,58,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-2.914,-4.147,1.233,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.0495842,0.00523369,0.0781844 beta-lactamase_G242D,beta-lactamase_242,TEM-1,beta-lactamase,P62593,0.078204,NO,242,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.319,-3.384,2.065,4.68003,,E,B,0.87,-1.05,1.079,,50,BOH,-1.428,0.221079,0.00452879,0.078204 beta-lactamase_G43F,beta-lactamase_43,TEM-1,beta-lactamase,P62593,0.078204,NO,43,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.62,-4.292,3.672,5.28886,,E,B,0.77,-0.78,,,,HOH,-1.577,0.221079,0.00120151,0.078204 kka2_1:8_G205E,kka2_1:8_205,Kka2,kka2_1:8,P00552,0.0782511,NO,205,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.596,-3.693,3.097,,,E,b,0.75,-1.05,,,,POH,-1.09933,0.100394,0.00221855,0.0782511 kka2_1:8_G205E,kka2_1:8_205,Kka2,kka2_1:8,P00552,0.0782511,NO,205,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.596,-3.693,3.097,,,E,b,0.75,-1.05,,,,POH,-1.09933,0.100394,0.00221855,0.0782511 beta-lactamase_156_K71N,beta-lactamase_156_71,TEM-1,beta-lactamase_156,P62593,0.078296,NO,71,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-0.8,-3.448,2.648,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.111618,0.00103192,0.078296 kka2_1:2_V214W,kka2_1:2_214,Kka2,kka2_1:2,P00552,0.0784923,NO,214,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.261,-5.433,4.172,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.295029,0.00692782,0.0784923 kka2_1:2_T225K,kka2_1:2_225,Kka2,kka2_1:2,P00552,0.0785645,NO,225,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.393,-3.78,1.387,,0.036,H,A,0.22,-1.22,4.554,,63.64,HPB,-1.58733,0.295029,0.0113598,0.0785645 kka2_1:4_T187H,kka2_1:4_187,Kka2,kka2_1:4,P00552,0.0785964,NO,187,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.273,-4.848,3.575,,0.007,E,B,0.22,-0.85,2.73,,52.27,HPB,-1.06567,0.168804,0.00693073,0.0785964 kka2_1:2_P179D,kka2_1:2_179,Kka2,kka2_1:2,P00552,0.0786194,NO,179,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.974,-3.655,2.681,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.295029,0.00298346,0.0786194 PSD95pdz3_I327G,PSD95pdz3_327,PSD95pdz3,PSD95pdz3,P31016,0.0786435,NO,327,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.63,-3.49,1.86,5.7413,,,,,14.0388,,,,PHH,-1.50167,0.0758425,0.000998774,0.0786435 kka2_1:2_T73G,kka2_1:2_73,Kka2,kka2_1:2,P00552,0.0786673,NO,73,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.51,-3.619,1.109,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.295029,0.00628605,0.0786673 beta-lactamase_2500_D161G,beta-lactamase_2500_161,TEM-1,beta-lactamase_2500,P62593,0.0788283,NO,161,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.891,-3.177,2.286,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.361275,0.000897697,0.0788283 beta-lactamase_A230K,beta-lactamase_230,TEM-1,beta-lactamase,P62593,0.0788428,NO,230,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.154,-3.583,2.429,4.54336,0.01,E,B,0.75,-1.17,1.97,,50,HHA,-1.079,0.221079,0.00516841,0.0788428 beta-lactamase_2500_L74F,beta-lactamase_2500_74,TEM-1,beta-lactamase_2500,P62593,0.0788634,NO,74,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.296,-3.848,2.552,,,H,A,0.55,-0.91,0.746,,50,HHO,-1.34933,0.361275,0.00493255,0.0788634 beta-lactamase_156_G43M,beta-lactamase_156_43,TEM-1,beta-lactamase_156,P62593,0.0788839,NO,43,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.62,-4.93,4.31,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.111618,0.00120151,0.0788839 beta-lactamase_156_S128D,beta-lactamase_156_128,TEM-1,beta-lactamase_156,P62593,0.0789827,NO,128,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-0.84,-3.244,2.404,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.111618,0.00071483,0.0789827 beta-lactamase_2500_S104Q,beta-lactamase_2500_104,TEM-1,beta-lactamase_2500,P62593,0.079049,NO,104,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.015,-3.815,2.8,,0.04,,b,0.27,0.57,1.133,,63.29,HPO,-1.05267,0.361275,0.00218083,0.079049 kka2_1:2_A117W,kka2_1:2_117,Kka2,kka2_1:2,P00552,0.0790817,NO,117,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.828,-5.385,4.557,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.295029,0.00282984,0.0790817 kka2_1:2_L232I,kka2_1:2_232,Kka2,kka2_1:2,P00552,0.0792974,NO,232,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.514,-2.661,1.147,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.295029,0.00800103,0.0792974 beta-lactamase_I275E,beta-lactamase_275,TEM-1,beta-lactamase,P62593,0.079305,NO,275,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.397,-3.894,2.497,5.3999,0.015,H,A,1,-0.52,0.836,,62.59,PHH,-1.541,0.221079,0.0141984,0.079305 beta-lactamase_2500_R242F,beta-lactamase_2500_242,TEM-1,beta-lactamase_2500,P62593,0.0793826,NO,242,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.361275,0.00452879,0.0793826 beta-lactamase_156_G243P,beta-lactamase_156_243,TEM-1,beta-lactamase_156,P62593,0.0793999,NO,243,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.532,,,,,E,B,0.77,-1.24,2.866,,50,BOH,-1.46867,0.111618,0.00464034,0.0793999 beta-lactamase_625_T107K,beta-lactamase_625_107,TEM-1,beta-lactamase_625,P62593,0.0794448,NO,107,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.117,-3.447,2.33,,,G,A,0.22,-0.06,3.676,,67.83,HPA,-1.265,0.213352,0.00239347,0.0794448 beta-lactamase_2500_K232S,beta-lactamase_2500_232,TEM-1,beta-lactamase_2500,P62593,0.0794596,NO,232,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.012,-3.258,2.246,,,E,B,2.34,-1.1,3.048,,65.03,ABP,-1.238,0.361275,0.00313441,0.0794596 beta-lactamase_2500_M115G,beta-lactamase_2500_115,TEM-1,beta-lactamase_2500,P62593,0.0794893,NO,115,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.389,-3.632,2.243,,0.019,E,B,0.55,0.08,3.261,,69.58,OHP,-1.25433,0.361275,0.0034337,0.0794893 kka2_1:4_M116Q,kka2_1:4_116,Kka2,kka2_1:4,P00552,0.0795898,NO,116,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-2.482,-4.256,1.774,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.168804,0.00745147,0.0795898 kka2_1:4_D261C,kka2_1:4_261,Kka2,kka2_1:4,P00552,0.0799437,NO,261,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.708,-5.115,4.407,,0.146,G,A,0.75,-0.33,,,,HAA,-0.759333,0.168804,0.0224846,0.0799437 beta-lactamase_625_E35F,beta-lactamase_625_35,TEM-1,beta-lactamase_625,P62593,0.0802921,NO,35,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-0.869,-4.318,3.449,,0.15,H,A,1.04,0.21,0.664,,46.85,HAA,-1.88667,0.213352,0.00174441,0.0802921 kka2_1:4_F48M,kka2_1:4_48,Kka2,kka2_1:4,P00552,0.0803335,NO,48,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.453,-4.369,2.916,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.168804,0.00475422,0.0803335 kka2_1:1_V97I,kka2_1:1_97,Kka2,kka2_1:1,P00552,0.0803499,NO,97,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.453,-2.403,0.95,,0.083,,B,1.48,-0.83,13.576,13.576,53.03,AHO,-1.85067,0.520039,0.00737869,0.0803499 beta-lactamase_N130P,beta-lactamase_130,TEM-1,beta-lactamase,P62593,0.0803941,NO,130,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-0.798,-3.88,3.082,5.26686,0.069,H,A,1.08,-0.74,,,,APP,-0.980667,0.221079,0.000683376,0.0803941 beta-lactamase_39_D177K,beta-lactamase_39_177,TEM-1,beta-lactamase_39,P62593,0.0805911,NO,177,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.967,-3.523,2.556,,0.006,T,L,0.75,-1.02,3.536,,64.69,BAP,-0.873667,0.0495842,0.000864022,0.0805911 kka2_1:1_L232C,kka2_1:1_232,Kka2,kka2_1:1,P00552,0.0806707,NO,232,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.514,-3.424,1.91,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.520039,0.00800103,0.0806707 beta-lactamase_625_L79W,beta-lactamase_625_79,TEM-1,beta-lactamase_625,P62593,0.080699,NO,79,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.842,-5.095,4.253,,0.007,H,A,0.55,-0.16,0.935,,50.35,HHP,-1.44333,0.213352,0.000947397,0.080699 beta-lactamase_2500_L74K,beta-lactamase_2500_74,TEM-1,beta-lactamase_2500,P62593,0.0807226,NO,74,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.296,-3.688,2.392,,,H,A,0.55,-0.91,0.746,,50,HHO,-1.34933,0.361275,0.00493255,0.0807226 kka2_1:8_W91E,kka2_1:8_91,Kka2,kka2_1:8,P00552,0.0809621,NO,91,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-1.178,-3.842,2.664,,0.077,E,B,1.51,0.27,2.51,,48.48,AHH,-1.51,0.100394,0.00358653,0.0809621 kka2_1:8_W91E,kka2_1:8_91,Kka2,kka2_1:8,P00552,0.0809621,NO,91,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-1.178,-3.842,2.664,,0.077,E,B,1.51,0.27,2.51,,48.48,AHH,-1.51,0.100394,0.00358653,0.0809621 kka2_1:1_G74Y,kka2_1:1_74,Kka2,kka2_1:1,P00552,0.0811844,NO,74,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.18,-4.468,3.288,,0.621,T,l,0.75,0.2,15.356,15.356,64.39,POH,-1.91667,0.520039,0.00587035,0.0811844 beta-lactamase_2500_E35R,beta-lactamase_2500_35,TEM-1,beta-lactamase_2500,P62593,0.0812382,NO,35,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-0.869,-3.551,2.682,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.361275,0.00174441,0.0812382 beta-lactamase_L79R,beta-lactamase_79,TEM-1,beta-lactamase,P62593,0.081325,NO,79,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.842,-3.93,3.088,4.98681,0.007,H,A,1.07,-0.16,0.823,,50.35,HHP,-1.44333,0.221079,0.000947397,0.081325 kka2_1:2_P194H,kka2_1:2_194,Kka2,kka2_1:2,P00552,0.0813765,NO,194,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.846,-4.708,3.862,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.295029,0.00314194,0.0813765 kka2_1:2_F263I,kka2_1:2_263,Kka2,kka2_1:2,P00552,0.0813813,NO,263,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-0.911,-3.319,2.408,,0.006,G,A,1.62,-0.12,5.275,,45.83,AHH,-0.92,0.295029,0.0172454,0.0813813 beta-lactamase_625_G76K,beta-lactamase_625_76,TEM-1,beta-lactamase_625,P62593,0.081528,NO,76,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.189,-3.631,2.442,,,H,A,0.29,-0.67,3.059,,67.83,OOH,-1.22267,0.213352,0.00476637,0.081528 beta-lactamase_625_L188R,beta-lactamase_625_188,TEM-1,beta-lactamase_625,P62593,0.0815959,NO,188,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.166,-3.976,2.81,,,H,A,0.55,-0.3,2.982,,60.14,PHB,-1.47033,0.213352,0.00295687,0.0815959 beta-lactamase_156_Y44Q,beta-lactamase_156_44,TEM-1,beta-lactamase_156,P62593,0.0816671,NO,44,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-2.547,-4.196,1.649,,,E,B,0.21,-0.45,2.184,,73.78,OHH,-1.86267,0.111618,0.00426364,0.0816671 beta-lactamase_V31R,beta-lactamase_31,TEM-1,beta-lactamase,P62593,0.0817238,NO,31,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.822,-4.173,2.351,5.43781,,H,A,2.78,-0.46,2.885,,73.78,BHB,-2.03767,0.221079,0.00478065,0.0817238 beta-lactamase_625_M209Y,beta-lactamase_625_209,TEM-1,beta-lactamase_625,P62593,0.0817851,NO,209,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.442,-3.865,2.423,,,H,A,0.55,-0.97,1.167,,64.69,HHA,-1.52633,0.213352,0.00625021,0.0817851 beta-lactamase_2500_V78R,beta-lactamase_2500_78,TEM-1,beta-lactamase_2500,P62593,0.0818041,NO,78,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.459,-4.181,2.722,,,H,A,0.44,-0.47,31.376,31.376,63.64,HHH,-1.17833,0.361275,0.00492501,0.0818041 beta-lactamase_2500_M66P,beta-lactamase_2500_66,TEM-1,beta-lactamase_2500,P62593,0.081875,NO,66,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.362,-4.047,2.685,,0.013,,A,0.55,-0.7,0.502,,73.08,OHH,-1.49567,0.361275,0.00412876,0.081875 beta-lactamase_2500_D174W,beta-lactamase_2500_174,TEM-1,beta-lactamase_2500,P62593,0.0820124,NO,174,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.738,-5.547,4.809,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.361275,0.00125633,0.0820124 beta-lactamase_625_G243K,beta-lactamase_625_243,TEM-1,beta-lactamase_625,P62593,0.0820887,NO,243,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.213352,0.00464034,0.0820887 kka2_1:4_V97P,kka2_1:4_97,Kka2,kka2_1:4,P00552,0.0821634,NO,97,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.453,-4.137,2.684,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.168804,0.00737869,0.0821634 beta-lactamase_Y44Q,beta-lactamase_44,TEM-1,beta-lactamase,P62593,0.0821842,NO,44,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-2.547,-4.196,1.649,5.6273,,E,B,2.55,-0.45,2.683,,73.78,OHH,-1.86267,0.221079,0.00426364,0.0821842 beta-lactamase_0_A123R,beta-lactamase_0_123,TEM-1,beta-lactamase_0,P62593,0.0823923,NO,123,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.834,-3.776,2.942,,0.039,H,A,0.46,-0.72,1.308,,41.26,PHH,-1.47367,0.0500837,0.0010157,0.0823923 beta-lactamase_2500_M153D,beta-lactamase_2500_153,TEM-1,beta-lactamase_2500,P62593,0.0825014,NO,153,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-3.193,-3.931,0.738,,0.14,T,A,0.55,-0.11,3.409,,77.62,PHO,-2.25767,0.361275,0.00509109,0.0825014 kka2_1:1_V75T,kka2_1:1_75,Kka2,kka2_1:1,P00552,0.0825417,NO,75,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-2.06,-2.915,0.855,,0.042,.,B,0.44,-0.2,2.815,,71.59,OHO,-1.563,0.520039,0.00693733,0.0825417 beta-lactamase_2500_G234K,beta-lactamase_2500_234,TEM-1,beta-lactamase_2500,P62593,0.0826592,NO,234,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.62,-3.682,3.062,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.361275,0.000889577,0.0826592 beta-lactamase_39_A246D,beta-lactamase_39_246,TEM-1,beta-lactamase_39,P62593,0.0827518,NO,246,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.121,-4.086,1.965,,0.01,E,B,0.46,-1.01,1.331,,73.78,HHH,-1.55633,0.0495842,0.00569458,0.0827518 beta-lactamase_156_R59I,beta-lactamase_156_59,TEM-1,beta-lactamase_156,P62593,0.0828315,NO,59,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.345,-4.065,2.72,,0.329,S,L,1.2,-0.09,2.995,,73.08,HBO,-2.24267,0.111618,0.00318082,0.0828315 beta-lactamase_625_A246H,beta-lactamase_625_246,TEM-1,beta-lactamase_625,P62593,0.0828436,NO,246,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.121,-4.964,2.843,,0.01,E,B,0.46,-1.01,1.201,,73.78,HHH,-1.55633,0.213352,0.00569458,0.0828436 beta-lactamase_2500_D155T,beta-lactamase_2500_155,TEM-1,beta-lactamase_2500,P62593,0.0828705,NO,155,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.889,-3.445,2.556,,0.049,,B,0.75,-0.9,2.386,,64.69,OAB,-1.62267,0.361275,0.00135315,0.0828705 kka2_1:2_D227K,kka2_1:2_227,Kka2,kka2_1:2,P00552,0.0831051,NO,227,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.758,-3.364,1.606,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.295029,0.00745029,0.0831051 beta-lactamase_2500_V259W,beta-lactamase_2500_259,TEM-1,beta-lactamase_2500,P62593,0.0831172,NO,259,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.361275,0.0070773,0.0831172 beta-lactamase_625_L205K,beta-lactamase_625_205,TEM-1,beta-lactamase_625,P62593,0.0833065,NO,205,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.922,-3.736,2.814,,,H,A,0.55,-0.46,3.782,,42.31,PHH,-1.57767,0.213352,0.00255802,0.0833065 kka2_1:2_N58E,kka2_1:2_58,Kka2,kka2_1:2,P00552,0.0833778,NO,58,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-2.641,-3.612,0.971,,0.131,S,A,0.43,0.72,5.729,,71.59,HPA,-1.83033,0.295029,0.00793425,0.0833778 beta-lactamase_K232C,beta-lactamase_232,TEM-1,beta-lactamase,P62593,0.0833967,NO,232,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.012,-5.13,4.118,5.18286,,E,B,2.92,-1.1,1.174,,65.03,ABP,-1.238,0.221079,0.00313441,0.0833967 beta-lactamase_625_A246K,beta-lactamase_625_246,TEM-1,beta-lactamase_625,P62593,0.0834085,NO,246,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.121,-3.849,1.728,,0.01,E,B,0.46,-1.01,1.201,,73.78,HHH,-1.55633,0.213352,0.00569458,0.0834085 beta-lactamase_2500_D177G,beta-lactamase_2500_177,TEM-1,beta-lactamase_2500,P62593,0.0834384,NO,177,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.967,-2.392,1.425,,0.006,T,L,0.75,-1.02,4.131,,64.69,BAP,-0.873667,0.361275,0.000864022,0.0834384 kka2_1:2_I228D,kka2_1:2_228,Kka2,kka2_1:2,P00552,0.0835033,NO,228,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.142,-4.061,2.919,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.295029,0.00458834,0.0835033 beta-lactamase_625_D177T,beta-lactamase_625_177,TEM-1,beta-lactamase_625,P62593,0.0835221,NO,177,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.967,-3.465,2.498,,0.006,T,L,0.75,-1.02,1.333,,64.69,BAP,-0.873667,0.213352,0.000864022,0.0835221 beta-lactamase_K232N,beta-lactamase_232,TEM-1,beta-lactamase,P62593,0.0836692,NO,232,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.012,-3.49,2.478,5.18286,,E,B,2.92,-1.1,1.174,,65.03,ABP,-1.238,0.221079,0.00313441,0.0836692 beta-lactamase_0_A123G,beta-lactamase_0_123,TEM-1,beta-lactamase_0,P62593,0.0838021,NO,123,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.834,-2.991,2.157,,0.039,H,A,0.46,-0.72,1.308,,41.26,PHH,-1.47367,0.0500837,0.0010157,0.0838021 beta-lactamase_39_A246H,beta-lactamase_39_246,TEM-1,beta-lactamase_39,P62593,0.0838152,NO,246,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.121,-4.964,2.843,,0.01,E,B,0.46,-1.01,1.331,,73.78,HHH,-1.55633,0.0495842,0.00569458,0.0838152 beta-lactamase_2500_D155S,beta-lactamase_2500_155,TEM-1,beta-lactamase_2500,P62593,0.0838589,NO,155,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.889,-3.185,2.296,,0.049,,B,0.75,-0.9,2.386,,64.69,OAB,-1.62267,0.361275,0.00135315,0.0838589 kka2_1:2_V153D,kka2_1:2_153,Kka2,kka2_1:2,P00552,0.0838928,NO,153,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.092,-4.005,2.913,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.295029,0.00501119,0.0838928 beta-lactamase_2500_I229S,beta-lactamase_2500_229,TEM-1,beta-lactamase_2500,P62593,0.083918,NO,229,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.267,-3.615,2.348,,0.083,E,B,0.48,-0.76,3.875,,50,HHH,-1.58767,0.361275,0.00477249,0.083918 kka2_1:1_L232E,kka2_1:1_232,Kka2,kka2_1:1,P00552,0.0839247,NO,232,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.514,-3.993,2.479,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.520039,0.00800103,0.0839247 beta-lactamase_2500_I245K,beta-lactamase_2500_245,TEM-1,beta-lactamase_2500,P62593,0.0839438,NO,245,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.361275,0.00391032,0.0839438 kka2_1:4_D190S,kka2_1:4_190,Kka2,kka2_1:4,P00552,0.0839684,NO,190,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.708,-3.189,2.481,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.168804,0.00247989,0.0839684 beta-lactamase_D177K,beta-lactamase_177,TEM-1,beta-lactamase,P62593,0.0841173,NO,177,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.967,-3.523,2.556,5.08038,0.006,T,L,1.59,-1.02,3.536,,64.69,BAP,-0.873667,0.221079,0.000864022,0.0841173 beta-lactamase_V31E,beta-lactamase_31,TEM-1,beta-lactamase,P62593,0.0841173,NO,31,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.822,-3.908,2.086,5.43781,,H,A,2.78,-0.46,2.885,,73.78,BHB,-2.03767,0.221079,0.00478065,0.0841173 beta-lactamase_L247R,beta-lactamase_247,TEM-1,beta-lactamase,P62593,0.08417,NO,247,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.48,-4.102,2.622,5.28771,0.007,E,B,2.89,-0.72,2.951,,63.99,HHO,-1.79833,0.221079,0.00611275,0.08417 kka2_1:8_F240Y,kka2_1:8_240,Kka2,kka2_1:8,P00552,0.084186,NO,240,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-0.911,-3.189,2.278,,,H,A,1.62,-1.21,0.697,,50.38,BHH,-1.67267,0.100394,0.00552543,0.084186 kka2_1:8_F240Y,kka2_1:8_240,Kka2,kka2_1:8,P00552,0.084186,NO,240,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-0.911,-3.189,2.278,,,H,A,1.62,-1.21,0.697,,50.38,BHH,-1.67267,0.100394,0.00552543,0.084186 kka2_1:1_R173F,kka2_1:1_173,Kka2,kka2_1:1,P00552,0.0842565,NO,173,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.407,-4.245,1.838,,0.308,H,A,0.16,-0.13,14.756,14.756,65.53,HBH,-1.70533,0.520039,0.00784999,0.0842565 beta-lactamase_A230E,beta-lactamase_230,TEM-1,beta-lactamase,P62593,0.0842723,NO,230,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.154,-3.566,2.412,4.54336,0.01,E,B,0.75,-1.17,1.97,,50,HHA,-1.079,0.221079,0.00516841,0.0842723 kka2_1:1_T72M,kka2_1:1_72,Kka2,kka2_1:1,P00552,0.0843169,NO,72,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.38,-3.59,1.21,,0.784,H,A,0.22,0.29,10.43,10.43,65.53,HPP,-2.238,0.520039,0.00750756,0.0843169 beta-lactamase_2500_M66K,beta-lactamase_2500_66,TEM-1,beta-lactamase_2500,P62593,0.0843227,NO,66,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.362,-3.657,2.295,,0.013,,A,0.55,-0.7,0.502,,73.08,OHH,-1.49567,0.361275,0.00412876,0.0843227 kka2_1:2_Y218N,kka2_1:2_218,Kka2,kka2_1:2,P00552,0.084372,NO,218,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-1.438,-3.871,2.433,,0.122,H,A,0.21,-0.69,1.022,,56.06,BHP,-1.17533,0.295029,0.0126098,0.084372 kka2_1:1_A79W,kka2_1:1_79,Kka2,kka2_1:1,P00552,0.0844414,NO,79,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.368,-5.595,3.227,,0.563,.,B,0.46,-0.43,7.792,7.792,71.59,HHH,-1.752,0.520039,0.00664821,0.0844414 beta-lactamase_I259Q,beta-lactamase_259,TEM-1,beta-lactamase,P62593,0.0845582,NO,259,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.522,-4.25,2.728,5.28457,,E,B,1,-0.8,1.24,,64.34,HHH,-1.53267,0.221079,0.0070773,0.0845582 beta-lactamase_2500_G43Y,beta-lactamase_2500_43,TEM-1,beta-lactamase_2500,P62593,0.0846649,NO,43,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.62,-4.387,3.767,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.361275,0.00120151,0.0846649 beta-lactamase_V78D,beta-lactamase_78,TEM-1,beta-lactamase,P62593,0.0846901,NO,78,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.459,-4.082,2.623,4.79197,,H,A,0.96,-0.47,1.132,,63.64,HHH,-1.17833,0.221079,0.00492501,0.0846901 kka2_1:1_L94H,kka2_1:1_94,Kka2,kka2_1:1,P00552,0.084703,NO,94,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.618,-4.931,3.313,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.520039,0.00520888,0.084703 kka2_1:4_F240M,kka2_1:4_240,Kka2,kka2_1:4,P00552,0.0847322,NO,240,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-0.911,-4.239,3.328,,,H,A,0.58,-1.21,5.798,,50.38,BHH,-1.67267,0.168804,0.00552543,0.0847322 beta-lactamase_156_E164A,beta-lactamase_156_164,TEM-1,beta-lactamase_156,P62593,0.0848023,NO,164,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-0.948,-3.102,2.154,,0.011,T,B,1.04,-0.4,3.445,,64.69,HAO,-1.388,0.111618,0.00137286,0.0848023 kka2_1:4_F203P,kka2_1:4_203,Kka2,kka2_1:4,P00552,0.084831,NO,203,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-0.911,-4.356,3.445,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.168804,0.00318738,0.084831 beta-lactamase_2500_G249K,beta-lactamase_2500_249,TEM-1,beta-lactamase_2500,P62593,0.0848389,NO,249,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.312,,,,0.256,S,B,0.23,0.04,30.841,30.841,72.73,HOO,-1.81367,0.361275,0.00220169,0.0848389 beta-lactamase_2500_L191E,beta-lactamase_2500_191,TEM-1,beta-lactamase_2500,P62593,0.0849348,NO,191,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.087,-3.859,2.772,,,H,A,0.55,0.09,1.703,,63.29,BHH,-1.445,0.361275,0.00263549,0.0849348 kka2_1:2_C77Q,kka2_1:2_77,Kka2,kka2_1:2,P00552,0.0849742,NO,77,C,Q,CQ,Special,Polar,5.07,6.24429,1.17429,154,121,146,25,108.5,143.8,35.3,-1.477,-4.277,2.8,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.295029,0.00441216,0.0849742 beta-lactamase_625_L146K,beta-lactamase_625_146,TEM-1,beta-lactamase_625,P62593,0.0851769,NO,146,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.462,-3.867,2.405,,0.007,H,A,0.55,-0.56,2.16,,64.69,AHP,-1.656,0.213352,0.00474542,0.0851769 beta-lactamase_2500_G43P,beta-lactamase_2500_43,TEM-1,beta-lactamase_2500,P62593,0.0852966,NO,43,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.62,-3.88,3.26,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.361275,0.00120151,0.0852966 beta-lactamase_39_K71T,beta-lactamase_39_71,TEM-1,beta-lactamase_39,P62593,0.0854132,NO,71,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-0.8,-3.421,2.621,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.0495842,0.00103192,0.0854132 beta-lactamase_156_I229P,beta-lactamase_156_229,TEM-1,beta-lactamase_156,P62593,0.0856185,NO,229,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.267,-4.079,2.812,,0.083,E,B,0.48,-0.76,1.114,,50,HHH,-1.58767,0.111618,0.00477249,0.0856185 kka2_1:4_A224H,kka2_1:4_224,Kka2,kka2_1:4,P00552,0.0856729,NO,224,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.977,-4.809,3.832,,,H,A,0.46,-1.26,0.93,,63.64,HHP,-1.41033,0.168804,0.00352047,0.0856729 kka2_1:4_F206D,kka2_1:4_206,Kka2,kka2_1:4,P00552,0.0858273,NO,206,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.349,-4.082,2.733,,0.006,E,B,0.58,-1.21,1.342,,63.64,OHH,-1.04,0.168804,0.00936868,0.0858273 beta-lactamase_39_A230D,beta-lactamase_39_230,TEM-1,beta-lactamase_39,P62593,0.0859254,NO,230,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.154,-3.645,2.491,,0.01,E,B,0.46,-1.17,1.171,,50,HHA,-1.079,0.0495842,0.00516841,0.0859254 beta-lactamase_2500_M184K,beta-lactamase_2500_184,TEM-1,beta-lactamase_2500,P62593,0.085958,NO,184,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.593,-3.659,2.066,,,H,A,0.55,-0.87,2.893,,62.94,HHH,-1.41,0.361275,0.00356019,0.085958 kka2_1:1_V186P,kka2_1:1_186,Kka2,kka2_1:1,P00552,0.0859982,NO,186,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.011,-4.069,3.058,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.520039,0.00409703,0.0859982 kka2_1:4_G233N,kka2_1:4_233,Kka2,kka2_1:4,P00552,0.086038,NO,233,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.748,-3.476,2.728,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.168804,0.00232366,0.086038 beta-lactamase_2500_G142P,beta-lactamase_2500_142,TEM-1,beta-lactamase_2500,P62593,0.0864398,NO,142,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.707,-3.877,3.17,,0.034,,p,0.29,-0.64,1.883,,64.69,OOO,-0.834,0.361275,0.00060149,0.0864398 kka2_1:4_D159K,kka2_1:4_159,Kka2,kka2_1:4,P00552,0.0864412,NO,159,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.82,-3.549,2.729,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.168804,0.0030485,0.0864412 WW_domain_Q200P,WW_domain_200,Yap65,WW_domain,P46937,0.0865223,NO,200,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-1.599,-3.589,1.99,5.37476,,,,,,1.9,,70.04,HPA,-1.484,0.153962,0.00300397,0.0865223 beta-lactamase_156_G43Q,beta-lactamase_156_43,TEM-1,beta-lactamase_156,P62593,0.0866068,NO,43,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.62,-4.124,3.504,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.111618,0.00120151,0.0866068 beta-lactamase_39_E164L,beta-lactamase_39_164,TEM-1,beta-lactamase_39,P62593,0.0866539,NO,164,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-0.948,-3.627,2.679,,0.011,T,B,1.04,-0.4,0.664,,64.69,HAO,-1.388,0.0495842,0.00137286,0.0866539 kka2_1:2_V49S,kka2_1:2_49,Kka2,kka2_1:2,P00552,0.0867226,NO,49,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.614,-2.896,1.282,,,E,B,0.44,-0.77,1.233,,64.39,HHB,-1.3,0.295029,0.00615685,0.0867226 PSD95pdz3_I341D,PSD95pdz3_341,PSD95pdz3,PSD95pdz3,P31016,0.0867446,NO,341,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.63,-3.6,1.97,5.73946,,,,,10.3187,,,,HHH,-1.50033,0.0758425,0.000824087,0.0867446 beta-lactamase_156_G243L,beta-lactamase_156_243,TEM-1,beta-lactamase_156,P62593,0.0870972,NO,243,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.532,,,,,E,B,0.77,-1.24,2.866,,50,BOH,-1.46867,0.111618,0.00464034,0.0870972 beta-lactamase_2500_P181K,beta-lactamase_2500_181,TEM-1,beta-lactamase_2500,P62593,0.0871189,NO,181,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.813,-3.483,2.67,,,H,A,0.52,-1.14,1.946,,61.54,HOH,-1.795,0.361275,0.000703122,0.0871189 beta-lactamase_156_S68Q,beta-lactamase_156_68,TEM-1,beta-lactamase_156,P62593,0.0873517,NO,68,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-0.913,-3.7,2.787,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.111618,0.000800065,0.0873517 kka2_1:4_D220Q,kka2_1:4_220,Kka2,kka2_1:4,P00552,0.0874095,NO,220,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.787,-3.763,2.976,,,H,A,0.75,-1.14,1.237,,46.59,PAH,-1.152,0.168804,0.00158066,0.0874095 beta-lactamase_625_G43P,beta-lactamase_625_43,TEM-1,beta-lactamase_625,P62593,0.0874194,NO,43,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.62,-3.88,3.26,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.213352,0.00120151,0.0874194 beta-lactamase_G248E,beta-lactamase_248,TEM-1,beta-lactamase,P62593,0.0874292,NO,248,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.794,-3.651,1.857,4.69798,,E,b,0.23,-0.43,1.782,,61.19,HOO,-1.52867,0.221079,0.00428493,0.0874292 beta-lactamase_T107K,beta-lactamase_107,TEM-1,beta-lactamase,P62593,0.0874292,NO,107,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.117,-3.447,2.33,5.23432,,G,A,2.12,-0.06,3.676,,67.83,HPA,-1.265,0.221079,0.00239347,0.0874292 beta-lactamase_0_V117G,beta-lactamase_0_117,TEM-1,beta-lactamase_0,P62593,0.0874642,NO,117,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.53,-3.828,2.298,,,H,A,0.44,-0.34,1.16,,65.03,PHB,-1.741,0.0500837,0.00467906,0.0874642 kka2_1:2_G233W,kka2_1:2_233,Kka2,kka2_1:2,P00552,0.0874748,NO,233,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.748,-5.239,4.491,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.295029,0.00232366,0.0874748 beta-lactamase_L136H,beta-lactamase_136,TEM-1,beta-lactamase,P62593,0.0875058,NO,136,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.232,-4.999,3.767,5.31114,,H,A,2.89,-0.34,1.539,,48.95,HHH,-1.088,0.221079,0.00442304,0.0875058 kka2_1:4_M116P,kka2_1:4_116,Kka2,kka2_1:4,P00552,0.087546,NO,116,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-2.482,-4.193,1.711,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.168804,0.00745147,0.087546 beta-lactamase_625_D177L,beta-lactamase_625_177,TEM-1,beta-lactamase_625,P62593,0.0875715,NO,177,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.967,-3.772,2.805,,0.006,T,L,0.75,-1.02,1.333,,64.69,BAP,-0.873667,0.213352,0.000864022,0.0875715 kka2_1:4_I207K,kka2_1:4_207,Kka2,kka2_1:4,P00552,0.087655,NO,207,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.175,-3.925,2.75,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.168804,0.00611824,0.087655 kka2_1:4_D183L,kka2_1:4_183,Kka2,kka2_1:4,P00552,0.0877852,NO,183,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.204,-3.71,2.506,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.168804,0.00426304,0.0877852 beta-lactamase_625_R257D,beta-lactamase_625_257,TEM-1,beta-lactamase_625,P62593,0.0877984,NO,257,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.213352,0.00756629,0.0877984 kka2_1:4_D208F,kka2_1:4_208,Kka2,kka2_1:4,P00552,0.0878417,NO,208,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.708,-4.32,3.612,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.168804,0.00212588,0.0878417 beta-lactamase_2500_S68L,beta-lactamase_2500_68,TEM-1,beta-lactamase_2500,P62593,0.0879888,NO,68,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-0.913,-3.407,2.494,,0.064,G,A,0.27,-1.03,2.824,,64.69,HPP,-1.37233,0.361275,0.000800065,0.0879888 beta-lactamase_2500_Y44C,beta-lactamase_2500_44,TEM-1,beta-lactamase_2500,P62593,0.0880176,NO,44,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-2.547,-4.829,2.282,,,E,B,0.21,-0.45,2.184,,73.78,OHH,-1.86267,0.361275,0.00426364,0.0880176 kka2_1:4_E199P,kka2_1:4_199,Kka2,kka2_1:4,P00552,0.088056,NO,199,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.234,-4.043,1.809,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.168804,0.00854122,0.088056 kka2_1:8_F263E,kka2_1:8_263,Kka2,kka2_1:8,P00552,0.0881719,NO,263,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-0.911,-3.952,3.041,,0.006,G,A,1.62,-0.12,0.928,,45.83,AHH,-0.92,0.100394,0.0172454,0.0881719 kka2_1:8_F263E,kka2_1:8_263,Kka2,kka2_1:8,P00552,0.0881719,NO,263,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-0.911,-3.952,3.041,,0.006,G,A,1.62,-0.12,0.928,,45.83,AHH,-0.92,0.100394,0.0172454,0.0881719 kka2_1:2_E59R,kka2_1:2_59,Kka2,kka2_1:2,P00552,0.0881858,NO,59,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-0.952,-3.602,2.65,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.295029,0.00280355,0.0881858 kka2_1:1_C77A,kka2_1:1_77,Kka2,kka2_1:1,P00552,0.0882883,NO,77,C,A,CA,Special,Hydrophobic,5.07,6,0.93,195,121,89,-32,108.5,88.6,-19.9,-1.477,-1.773,0.296,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.520039,0.00441216,0.0882883 beta-lactamase_2500_F64G,beta-lactamase_2500_64,TEM-1,beta-lactamase_2500,P62593,0.0882972,NO,64,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-0.841,-3.583,2.742,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.361275,0.000947691,0.0882972 Pab1_F129M,Pab1_129,Pab1,Pab1,P04147,0.0884194,NO,129,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.269,-4.176,2.907,,0.219,E,B,0.03,-0.07,1.307,,73.83,HHH,-1.27533,0.175299,0.000625182,0.0884194 beta-lactamase_2500_W208P,beta-lactamase_2500_208,TEM-1,beta-lactamase_2500,P62593,0.0884841,NO,208,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-0.818,-4.33,3.512,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.361275,0.00126609,0.0884841 kka2_1:4_A222F,kka2_1:4_222,Kka2,kka2_1:4,P00552,0.0885227,NO,222,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.725,-4.095,3.37,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.168804,0.00207657,0.0885227 beta-lactamase_2500_L218S,beta-lactamase_2500_218,TEM-1,beta-lactamase_2500,P62593,0.0885336,NO,218,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.391,-2.79,1.399,,,I,b,0.55,-0.53,9.151,9.151,74.48,OHH,-1.58867,0.361275,0.00618274,0.0885336 beta-lactamase_2500_S233R,beta-lactamase_2500_233,TEM-1,beta-lactamase_2500,P62593,0.0885486,NO,233,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.886,-3.819,1.933,,0.016,E,B,0.27,-1.01,2.851,,77.62,BPO,-1.17267,0.361275,0.00311415,0.0885486 kka2_1:2_G233H,kka2_1:2_233,Kka2,kka2_1:2,P00552,0.0886332,NO,233,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.748,-4.708,3.96,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.295029,0.00232366,0.0886332 beta-lactamase_625_R257Y,beta-lactamase_625_257,TEM-1,beta-lactamase_625,P62593,0.0886726,NO,257,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.213352,0.00756629,0.0886726 Ubiquitin_Q41P,Ubiquitin_41,Uba1,Ubiquitin,P0CG48,0.0887097,NO,41,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-1.329,-3.817,2.488,4.9201,0.017,E,B,0.12,-0.98,0.812,,30.07,PPB,-1.55067,0.205827,0.000521668,0.0887097 Ubiquitin_T9W,Ubiquitin_9,Uba1,Ubiquitin,P0CG48,0.0887097,NO,9,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.409,-5.254,3.845,5.24336,0.777,T,A,2.12,-0.12,2.705,,29.93,HPO,-1.50933,0.205827,0.000630716,0.0887097 kka2_1:4_E59I,kka2_1:4_59,Kka2,kka2_1:4,P00552,0.0888325,NO,59,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-0.952,-4.057,3.105,,0.187,.,L,1.04,0.62,3.408,,50.38,PAH,-1.53,0.168804,0.00280355,0.0888325 kka2_1:1_L259F,kka2_1:1_259,Kka2,kka2_1:1,P00552,0.0890099,NO,259,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.088,-3.817,2.729,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.520039,0.0206964,0.0890099 beta-lactamase_39_S128W,beta-lactamase_39_128,TEM-1,beta-lactamase_39,P62593,0.0890692,NO,128,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-0.84,-5.322,4.482,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.0495842,0.00071483,0.0890692 PSD95pdz3_I327C,PSD95pdz3_327,PSD95pdz3,PSD95pdz3,P31016,0.089175,NO,327,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.63,-4.319,2.689,5.7413,,,,,14.0388,,,,PHH,-1.50167,0.0758425,0.000998774,0.089175 beta-lactamase_39_E164V,beta-lactamase_39_164,TEM-1,beta-lactamase_39,P62593,0.0892068,NO,164,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-0.948,-3.599,2.651,,0.011,T,B,1.04,-0.4,0.664,,64.69,HAO,-1.388,0.0495842,0.00137286,0.0892068 kka2_1:4_D220I,kka2_1:4_220,Kka2,kka2_1:4,P00552,0.0892887,NO,220,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.787,-3.808,3.021,,,H,A,0.75,-1.14,1.237,,46.59,PAH,-1.152,0.168804,0.00158066,0.0892887 beta-lactamase_2500_M66E,beta-lactamase_2500_66,TEM-1,beta-lactamase_2500,P62593,0.089322,NO,66,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.362,-3.832,2.47,,0.013,,A,0.55,-0.7,0.502,,73.08,OHH,-1.49567,0.361275,0.00412876,0.089322 kka2_1:4_C77M,kka2_1:4_77,Kka2,kka2_1:4,P00552,0.0895003,NO,77,C,M,CM,Special,Hydrophobic,5.07,5.74,0.67,196,121,149,28,108.5,162.9,54.4,-1.477,-4.643,3.166,,0.229,B,b,0.46,-0.57,2.499,,63.26,OOH,-1.55667,0.168804,0.00441216,0.0895003 beta-lactamase_156_A185W,beta-lactamase_156_185,TEM-1,beta-lactamase_156,P62593,0.089562,NO,185,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.406,-5.387,3.981,,,H,A,0.46,-1.02,0.365,,65.03,HHP,-1.84033,0.111618,0.00467449,0.089562 beta-lactamase_C18I,beta-lactamase_18,TEM-1,beta-lactamase,P62593,0.089702,NO,18,C,I,CI,Special,Hydrophobic,5.07,6.02,0.95,198,121,131,10,108.5,166.7,58.2,-2.26,-3.862,1.602,,,,,,,3.995,,93.01,HOH,-2.093,0.221079,0.002536,0.089702 beta-lactamase_D155L,beta-lactamase_155,TEM-1,beta-lactamase,P62593,0.089702,NO,155,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.889,-3.807,2.918,4.92265,0.049,,B,0.45,-0.9,3.208,,64.69,OAB,-1.62267,0.221079,0.00135315,0.089702 beta-lactamase_D155Y,beta-lactamase_155,TEM-1,beta-lactamase,P62593,0.089702,NO,155,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.889,-4.387,3.498,4.92265,0.049,,B,0.45,-0.9,3.208,,64.69,OAB,-1.62267,0.221079,0.00135315,0.089702 beta-lactamase_D177P,beta-lactamase_177,TEM-1,beta-lactamase,P62593,0.089702,NO,177,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.967,-3.764,2.797,5.08038,0.006,T,L,1.59,-1.02,3.536,,64.69,BAP,-0.873667,0.221079,0.000864022,0.089702 beta-lactamase_D33P,beta-lactamase_33,TEM-1,beta-lactamase,P62593,0.089702,NO,33,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.321,-3.968,1.647,5.05203,0.366,H,A,0.23,0.33,2.032,,77.62,BAH,-2.12133,0.221079,0.00435556,0.089702 beta-lactamase_E164P,beta-lactamase_164,TEM-1,beta-lactamase,P62593,0.089702,NO,164,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-0.948,-3.725,2.777,5.3334,0.011,T,B,1.62,-0.4,1.055,,64.69,HAO,-1.388,0.221079,0.00137286,0.089702 beta-lactamase_E35P,beta-lactamase_35,TEM-1,beta-lactamase,P62593,0.089702,NO,35,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-0.869,-3.68,2.811,5.10723,0.15,H,A,0.52,0.21,1.081,,46.85,HAA,-1.88667,0.221079,0.00174441,0.089702 beta-lactamase_F13D,beta-lactamase_13,TEM-1,beta-lactamase,P62593,0.089702,NO,13,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-2.394,-3.742,1.348,,,,,,,4.079,,77.62,OHH,-2.382,0.221079,0.0029078,0.089702 beta-lactamase_F14R,beta-lactamase_14,TEM-1,beta-lactamase,P62593,0.089702,NO,14,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-2.736,-4.059,1.323,,,,,,,1.537,,93.01,HHH,-2.26133,0.221079,0.00277095,0.089702 beta-lactamase_F228P,beta-lactamase_228,TEM-1,beta-lactamase,P62593,0.089702,NO,228,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-2.342,-3.088,0.746,5.33448,0.154,E,B,1.1,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.221079,0.0046669,0.089702 beta-lactamase_L192D,beta-lactamase_192,TEM-1,beta-lactamase,P62593,0.089702,NO,192,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.254,-4.104,2.85,5.68899,0.095,H,A,1.3,0.35,1.756,,60.14,HHP,-1.41833,0.221079,0.00558728,0.089702 beta-lactamase_L192R,beta-lactamase_192,TEM-1,beta-lactamase,P62593,0.089702,NO,192,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.254,-4.095,2.841,5.68899,0.095,H,A,1.3,0.35,1.756,,60.14,HHP,-1.41833,0.221079,0.00558728,0.089702 beta-lactamase_M184W,beta-lactamase_184,TEM-1,beta-lactamase,P62593,0.089702,NO,184,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.593,-5.149,3.556,5.39575,,H,A,1.3,-0.87,2.893,,62.94,HHH,-1.41,0.221079,0.00356019,0.089702 beta-lactamase_M1H,beta-lactamase_1,TEM-1,beta-lactamase,P62593,0.089702,NO,1,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.998,-4.362,2.364,,,,,,,,,,OHP,-1.97,0.221079,0.00162771,0.089702 beta-lactamase_T69F,beta-lactamase_69,TEM-1,beta-lactamase,P62593,0.089702,NO,69,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-0.973,-4.127,3.154,5.16042,,G,A,0.69,-1.24,0.505,,93.01,PPH,-1.01833,0.221079,0.00127498,0.089702 beta-lactamase_V31Q,beta-lactamase_31,TEM-1,beta-lactamase,P62593,0.089702,NO,31,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.822,-4.296,2.474,5.43781,,H,A,2.78,-0.46,2.885,,73.78,BHB,-2.03767,0.221079,0.00478065,0.089702 beta-lactamase_2500_F64D,beta-lactamase_2500_64,TEM-1,beta-lactamase_2500,P62593,0.0897217,NO,64,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-0.841,-3.919,3.078,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.361275,0.000947691,0.0897217 kka2_1:8_I221Y,kka2_1:8_221,Kka2,kka2_1:8,P00552,0.0897528,NO,221,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.739,-4.012,2.273,,,H,A,1.52,-1.15,1.599,,71.59,AHH,-1.08367,0.100394,0.00945908,0.0897528 kka2_1:8_I221Y,kka2_1:8_221,Kka2,kka2_1:8,P00552,0.0897528,NO,221,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.739,-4.012,2.273,,,H,A,1.52,-1.15,1.599,,71.59,AHH,-1.08367,0.100394,0.00945908,0.0897528 beta-lactamase_156_G43F,beta-lactamase_156_43,TEM-1,beta-lactamase_156,P62593,0.0897768,NO,43,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.62,-4.292,3.672,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.111618,0.00120151,0.0897768 beta-lactamase_156_D177V,beta-lactamase_156_177,TEM-1,beta-lactamase_156,P62593,0.0898107,NO,177,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.967,-3.739,2.772,,0.006,T,L,0.75,-1.02,2.072,,64.69,BAP,-0.873667,0.111618,0.000864022,0.0898107 kka2_1:1_G10I,kka2_1:1_10,Kka2,kka2_1:1,P00552,0.0899882,NO,10,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.921,-4.096,2.175,,,,,,,1.862,,71.59,HOP,-2.10733,0.520039,0.00289233,0.0899882 kka2_1:1_L232W,kka2_1:1_232,Kka2,kka2_1:1,P00552,0.0900508,NO,232,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.514,-3.426,1.912,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.520039,0.00800103,0.0900508 kka2_1:4_L260N,kka2_1:4_260,Kka2,kka2_1:4,P00552,0.0900614,NO,260,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.741,-4.151,3.41,,0.022,H,A,0.55,-0.52,,,,HHA,-0.845667,0.168804,0.0233782,0.0900614 kka2_1:2_K112C,kka2_1:2_112,Kka2,kka2_1:2,P00552,0.090063,NO,112,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-2.491,-3.546,1.055,,0.076,H,A,2.34,-1.37,23.433,23.433,56.06,ABH,-2.00133,0.295029,0.00645389,0.090063 beta-lactamase_625_V259R,beta-lactamase_625_259,TEM-1,beta-lactamase_625,P62593,0.0900734,NO,259,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.213352,0.0070773,0.0900734 beta-lactamase_625_V259D,beta-lactamase_625_259,TEM-1,beta-lactamase_625,P62593,0.0901566,NO,259,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.213352,0.0070773,0.0901566 beta-lactamase_2500_N134R,beta-lactamase_2500_134,TEM-1,beta-lactamase_2500,P62593,0.0901847,NO,134,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-0.879,-3.446,2.567,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.361275,0.000644786,0.0901847 beta-lactamase_625_G43V,beta-lactamase_625_43,TEM-1,beta-lactamase_625,P62593,0.0902733,NO,43,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.62,-3.754,3.134,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.213352,0.00120151,0.0902733 beta-lactamase_625_D177W,beta-lactamase_625_177,TEM-1,beta-lactamase_625,P62593,0.0903236,NO,177,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.967,-5.545,4.578,,0.006,T,L,0.75,-1.02,1.333,,64.69,BAP,-0.873667,0.213352,0.000864022,0.0903236 beta-lactamase_625_K232P,beta-lactamase_625_232,TEM-1,beta-lactamase_625,P62593,0.0903381,NO,232,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.012,-3.752,2.74,,,E,B,2.34,-1.1,1.992,,65.03,ABP,-1.238,0.213352,0.00313441,0.0903381 kka2_1:4_F263M,kka2_1:4_263,Kka2,kka2_1:4,P00552,0.0903578,NO,263,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-0.911,-4.239,3.328,,0.006,G,A,0.58,-0.12,2.284,,45.83,AHH,-0.92,0.168804,0.0172454,0.0903578 beta-lactamase_625_L74Y,beta-lactamase_625_74,TEM-1,beta-lactamase_625,P62593,0.0904109,NO,74,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.296,-4.105,2.809,,,H,A,0.55,-0.91,0.895,,50,HHO,-1.34933,0.213352,0.00493255,0.0904109 beta-lactamase_2500_G236Q,beta-lactamase_2500_236,TEM-1,beta-lactamase_2500,P62593,0.0904581,NO,236,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.784,-4.093,3.309,,0.241,,b,0.29,-0.59,2.14,,64.69,HOO,-1.025,0.361275,0.00162372,0.0904581 beta-lactamase_D129S,beta-lactamase_129,TEM-1,beta-lactamase,P62593,0.0904902,NO,129,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.816,-3.186,2.37,4.84204,,,B,1.33,-0.69,0.548,,34.97,PAP,-0.818,0.221079,0.00109178,0.0904902 kka2_1:2_D190Q,kka2_1:2_190,Kka2,kka2_1:2,P00552,0.0905118,NO,190,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.708,-3.703,2.995,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.295029,0.00247989,0.0905118 kka2_1:4_M116E,kka2_1:4_116,Kka2,kka2_1:4,P00552,0.0905363,NO,116,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-2.482,-3.963,1.481,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.168804,0.00745147,0.0905363 beta-lactamase_39_L248D,beta-lactamase_39_248,TEM-1,beta-lactamase_39,P62593,0.0905953,NO,248,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.0495842,0.00428493,0.0905953 Pab1_G150F,Pab1_150,Pab1,Pab1,P04147,0.0906145,NO,150,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.809,-4.109,3.3,,0.287,S,b,0.23,0.53,,,,HOA,-1.45233,0.175299,0.000323835,0.0906145 kka2_1:2_F240I,kka2_1:2_240,Kka2,kka2_1:2,P00552,0.0906502,NO,240,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-0.911,-3.319,2.408,,,H,A,0.58,-1.21,0.373,,50.38,BHH,-1.67267,0.295029,0.00552543,0.0906502 kka2_1:4_V113K,kka2_1:4_113,Kka2,kka2_1:4,P00552,0.0907416,NO,113,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.233,-3.874,2.641,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.168804,0.00650191,0.0907416 kka2_1:2_C77Y,kka2_1:2_77,Kka2,kka2_1:2,P00552,0.0908416,NO,77,C,Y,CY,Special,Hydrophobic,5.07,5.66,0.59,194,121,181,60,108.5,193.6,85.1,-1.477,-4.33,2.853,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.295029,0.00441216,0.0908416 kka2_1:2_E182Y,kka2_1:2_182,Kka2,kka2_1:2,P00552,0.0908416,NO,182,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.516,-3.156,1.64,,0.326,,B,1.52,0.75,14.547,14.547,65.53,OAA,-1.806,0.295029,0.00641548,0.0908416 beta-lactamase_2500_L136N,beta-lactamase_2500_136,TEM-1,beta-lactamase_2500,P62593,0.0908603,NO,136,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.232,-4.217,2.985,,,H,A,0.55,-0.34,1.36,,48.95,HHH,-1.088,0.361275,0.00442304,0.0908603 kka2_1:1_A41L,kka2_1:1_41,Kka2,kka2_1:1,P00552,0.0909447,NO,41,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.879,-3.033,1.154,,0.184,.,B,0.46,-0.96,18.207,18.207,64.39,PHP,-2.477,0.520039,0.00543332,0.0909447 kka2_1:2_M197Y,kka2_1:2_197,Kka2,kka2_1:2,P00552,0.0909899,NO,197,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.707,-4.145,2.438,,0.121,E,B,0.55,-1.19,2.097,,65.53,HHH,-1.847,0.295029,0.00921295,0.0909899 kka2_1:2_H135G,kka2_1:2_135,Kka2,kka2_1:2,P00552,0.0912648,NO,135,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-1.331,-3.471,2.14,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.295029,0.00532566,0.0912648 beta-lactamase_625_G234K,beta-lactamase_625_234,TEM-1,beta-lactamase_625,P62593,0.0912691,NO,234,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.62,-3.682,3.062,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.213352,0.000889577,0.0912691 kka2_1:1_V80K,kka2_1:1_80,Kka2,kka2_1:1,P00552,0.0912763,NO,80,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.144,-3.802,2.658,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.520039,0.00488211,0.0912763 beta-lactamase_K232T,beta-lactamase_232,TEM-1,beta-lactamase,P62593,0.0912783,NO,232,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.012,-3.464,2.452,5.18286,,E,B,2.92,-1.1,1.174,,65.03,ABP,-1.238,0.221079,0.00313441,0.0912783 beta-lactamase_156_S68V,beta-lactamase_156_68,TEM-1,beta-lactamase_156,P62593,0.0913202,NO,68,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-0.913,-3.578,2.665,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.111618,0.000800065,0.0913202 beta-lactamase_2500_A185H,beta-lactamase_2500_185,TEM-1,beta-lactamase_2500,P62593,0.0914363,NO,185,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.406,-4.889,3.483,,,H,A,0.46,-1.02,2.999,,65.03,HHP,-1.84033,0.361275,0.00467449,0.0914363 beta-lactamase_A124D,beta-lactamase_124,TEM-1,beta-lactamase,P62593,0.0915119,NO,124,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.181,-3.709,2.528,4.58507,,H,A,0.58,-0.9,2.273,,64.34,HHH,-1.152,0.221079,0.00481399,0.0915119 PSD95pdz3_G329E,PSD95pdz3_329,PSD95pdz3,PSD95pdz3,P31016,0.0916053,NO,329,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.008,-3.347,2.339,4.7671,,,,,19.7075,,,,HOO,-1.16033,0.0758425,0.000974577,0.0916053 kka2_1:2_G233F,kka2_1:2_233,Kka2,kka2_1:2,P00552,0.0916723,NO,233,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.748,-4.365,3.617,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.295029,0.00232366,0.0916723 beta-lactamase_39_D177M,beta-lactamase_39_177,TEM-1,beta-lactamase_39,P62593,0.0918182,NO,177,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.967,-4.928,3.961,,0.006,T,L,0.75,-1.02,3.536,,64.69,BAP,-0.873667,0.0495842,0.000864022,0.0918182 kka2_1:1_Q219N,kka2_1:1_219,Kka2,kka2_1:1,P00552,0.0918515,NO,219,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-0.93,-3.499,2.569,,0.088,H,A,0.4,-0.85,1.917,,50,HPA,-1.05167,0.520039,0.00237913,0.0918515 kka2_1:2_M197S,kka2_1:2_197,Kka2,kka2_1:2,P00552,0.0918519,NO,197,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.707,-3.643,1.936,,0.121,E,B,0.55,-1.19,2.097,,65.53,HHH,-1.847,0.295029,0.00921295,0.0918519 beta-lactamase_2500_L136P,beta-lactamase_2500_136,TEM-1,beta-lactamase_2500,P62593,0.0919462,NO,136,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.232,-4.152,2.92,,,H,A,0.55,-0.34,1.36,,48.95,HHH,-1.088,0.361275,0.00442304,0.0919462 kka2_1:4_H124G,kka2_1:4_124,Kka2,kka2_1:4,P00552,0.0920148,NO,124,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-0.84,-3.386,2.546,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.168804,0.00211296,0.0920148 beta-lactamase_2500_C75Q,beta-lactamase_2500_75,TEM-1,beta-lactamase_2500,P62593,0.0920239,NO,75,C,Q,CQ,Special,Polar,5.07,6.24429,1.17429,154,121,146,25,108.5,143.8,35.3,-1.245,-4.228,2.983,,,H,A,0.46,-0.87,0.844,,50,HOO,-1.24333,0.361275,0.0034616,0.0920239 kka2_1:2_P179E,kka2_1:2_179,Kka2,kka2_1:2,P00552,0.092025,NO,179,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.974,-3.589,2.615,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.295029,0.00298346,0.092025 beta-lactamase_39_D177P,beta-lactamase_39_177,TEM-1,beta-lactamase_39,P62593,0.0921101,NO,177,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.967,-3.764,2.797,,0.006,T,L,0.75,-1.02,3.536,,64.69,BAP,-0.873667,0.0495842,0.000864022,0.0921101 beta-lactamase_39_T179W,beta-lactamase_39_179,TEM-1,beta-lactamase_39,P62593,0.0921903,NO,179,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.085,-5.211,4.126,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.0495842,0.00226045,0.0921903 kka2_1:4_G30I,kka2_1:4_30,Kka2,kka2_1:4,P00552,0.0922375,NO,30,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.596,-4.264,3.668,,0.54,S,g,0.29,3.76,,,,HOO,-1.51133,0.168804,0.00159208,0.0922375 beta-lactamase_625_L136H,beta-lactamase_625_136,TEM-1,beta-lactamase_625,P62593,0.0922709,NO,136,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.232,-4.999,3.767,,,H,A,0.55,-0.34,0.336,,48.95,HHH,-1.088,0.213352,0.00442304,0.0922709 beta-lactamase_I244H,beta-lactamase_244,TEM-1,beta-lactamase,P62593,0.0923675,NO,244,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.555,-4.957,3.402,5.35885,,E,B,0.01,-0.84,0.379,,77.62,HHH,-1.385,0.221079,0.00605379,0.0923675 beta-lactamase_39_T179N,beta-lactamase_39_179,TEM-1,beta-lactamase_39,P62593,0.092406,NO,179,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.085,-3.487,2.402,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.0495842,0.00226045,0.092406 beta-lactamase_625_I280Y,beta-lactamase_625_280,TEM-1,beta-lactamase_625,P62593,0.0924091,NO,280,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.213352,0.0530888,0.0924091 kka2_1:4_G189S,kka2_1:4_189,Kka2,kka2_1:4,P00552,0.0925108,NO,189,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.596,-3.189,2.593,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.168804,0.00253688,0.0925108 beta-lactamase_625_T158Y,beta-lactamase_625_158,TEM-1,beta-lactamase_625,P62593,0.0926132,NO,158,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.116,-4.258,3.142,,0.036,,B,0.22,-0.85,3.771,,69.58,HPB,-1.269,0.213352,0.00341825,0.0926132 kka2_1:8_G233I,kka2_1:8_233,Kka2,kka2_1:8,P00552,0.092892,NO,233,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.748,-4.263,3.515,,0.172,,b,0.75,-0.27,1.134,,49.24,HOO,-1.72067,0.100394,0.00232366,0.092892 kka2_1:8_G233I,kka2_1:8_233,Kka2,kka2_1:8,P00552,0.092892,NO,233,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.748,-4.263,3.515,,0.172,,b,0.75,-0.27,1.134,,49.24,HOO,-1.72067,0.100394,0.00232366,0.092892 beta-lactamase_156_I280D,beta-lactamase_156_280,TEM-1,beta-lactamase_156,P62593,0.0929298,NO,280,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.111618,0.0530888,0.0929298 beta-lactamase_625_L188P,beta-lactamase_625_188,TEM-1,beta-lactamase_625,P62593,0.0929868,NO,188,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.166,-4.109,2.943,,,H,A,0.55,-0.3,2.982,,60.14,PHB,-1.47033,0.213352,0.00295687,0.0929868 kka2_1:1_G189H,kka2_1:1_189,Kka2,kka2_1:1,P00552,0.0930775,NO,189,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.596,-4.708,4.112,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.520039,0.00253688,0.0930775 beta-lactamase_2500_A124H,beta-lactamase_2500_124,TEM-1,beta-lactamase_2500,P62593,0.0931197,NO,124,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.181,-4.785,3.604,,,H,A,0.46,-0.9,0.314,,64.34,HHH,-1.152,0.361275,0.00481399,0.0931197 beta-lactamase_2500_A34R,beta-lactamase_2500_34,TEM-1,beta-lactamase_2500,P62593,0.0931889,NO,34,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.059,-4.061,2.002,,,H,A,0.46,-0.54,2.921,,73.78,AHA,-1.74967,0.361275,0.00407913,0.0931889 beta-lactamase_156_V259D,beta-lactamase_156_259,TEM-1,beta-lactamase_156,P62593,0.093252,NO,259,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.111618,0.0070773,0.093252 beta-lactamase_2500_G249T,beta-lactamase_2500_249,TEM-1,beta-lactamase_2500,P62593,0.0932916,NO,249,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.312,,,,0.256,S,B,0.23,0.04,30.841,30.841,72.73,HOO,-1.81367,0.361275,0.00220169,0.0932916 kka2_1:1_P194W,kka2_1:1_194,Kka2,kka2_1:1,P00552,0.0932994,NO,194,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.846,-5.598,4.752,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.520039,0.00314194,0.0932994 beta-lactamase_625_A133R,beta-lactamase_625_133,TEM-1,beta-lactamase_625,P62593,0.0932997,NO,133,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.186,-3.865,2.679,,,H,A,0.46,-0.86,0.373,,67.83,HHP,-0.988333,0.213352,0.00468022,0.0932997 beta-lactamase_39_L74R,beta-lactamase_39_74,TEM-1,beta-lactamase_39,P62593,0.0933118,NO,74,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.296,-3.939,2.643,,,H,A,0.55,-0.91,1.581,,50,HHO,-1.34933,0.0495842,0.00493255,0.0933118 beta-lactamase_2500_G236P,beta-lactamase_2500_236,TEM-1,beta-lactamase_2500,P62593,0.0933224,NO,236,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.784,-3.879,3.095,,0.241,,b,0.29,-0.59,2.14,,64.69,HOO,-1.025,0.361275,0.00162372,0.0933224 beta-lactamase_2500_D155K,beta-lactamase_2500_155,TEM-1,beta-lactamase_2500,P62593,0.0933538,NO,155,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.889,-3.426,2.537,,0.049,,B,0.75,-0.9,2.386,,64.69,OAB,-1.62267,0.361275,0.00135315,0.0933538 kka2_1:8_F256N,kka2_1:8_256,Kka2,kka2_1:8,P00552,0.0934123,NO,256,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.49,-4.16,2.67,,,H,A,1.62,-0.78,1.713,,53.03,HHH,-1.423,0.100394,0.0132841,0.0934123 kka2_1:8_F256N,kka2_1:8_256,Kka2,kka2_1:8,P00552,0.0934123,NO,256,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.49,-4.16,2.67,,,H,A,1.62,-0.78,1.713,,53.03,HHH,-1.423,0.100394,0.0132841,0.0934123 beta-lactamase_156_A133K,beta-lactamase_156_133,TEM-1,beta-lactamase_156,P62593,0.0935641,NO,133,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.186,-3.614,2.428,,,H,A,0.46,-0.86,0.805,,67.83,HHP,-0.988333,0.111618,0.00468022,0.0935641 beta-lactamase_2500_R81P,beta-lactamase_2500_81,TEM-1,beta-lactamase_2500,P62593,0.093583,NO,81,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.466,-3.949,2.483,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.361275,0.00499763,0.093583 kka2_1:1_P76N,kka2_1:1_76,Kka2,kka2_1:1,P00552,0.0936242,NO,76,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.449,-3.923,2.474,,0.331,.,B,0.52,-0.41,0.345,,63.64,HOO,-1.662,0.520039,0.00625685,0.0936242 kka2_1:8_L259F,kka2_1:8_259,Kka2,kka2_1:8,P00552,0.0936721,NO,259,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.088,-3.817,2.729,,0.036,H,A,1.59,-0.15,1.83,,48.48,BHH,-1.15167,0.100394,0.0206964,0.0936721 kka2_1:8_L259F,kka2_1:8_259,Kka2,kka2_1:8,P00552,0.0936721,NO,259,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.088,-3.817,2.729,,0.036,H,A,1.59,-0.15,1.83,,48.48,BHH,-1.15167,0.100394,0.0206964,0.0936721 kka2_1:4_F48E,kka2_1:4_48,Kka2,kka2_1:4,P00552,0.0936863,NO,48,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.453,-3.968,2.515,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.168804,0.00475422,0.0936863 beta-lactamase_2500_K71Y,beta-lactamase_2500_71,TEM-1,beta-lactamase_2500,P62593,0.0936935,NO,71,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-0.8,-4.162,3.362,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.361275,0.00103192,0.0936935 beta-lactamase_0_A123S,beta-lactamase_0_123,TEM-1,beta-lactamase_0,P62593,0.0937173,NO,123,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.834,-3.019,2.185,,0.039,H,A,0.46,-0.72,1.308,,41.26,PHH,-1.47367,0.0500837,0.0010157,0.0937173 kka2_1:1_V214P,kka2_1:1_214,Kka2,kka2_1:1,P00552,0.093741,NO,214,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.261,-4.14,2.879,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.520039,0.00692782,0.093741 beta-lactamase_156_K71A,beta-lactamase_156_71,TEM-1,beta-lactamase_156,P62593,0.0937595,NO,71,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-0.8,-3.078,2.278,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.111618,0.00103192,0.0937595 beta-lactamase_156_D177T,beta-lactamase_156_177,TEM-1,beta-lactamase_156,P62593,0.0938601,NO,177,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.967,-3.465,2.498,,0.006,T,L,0.75,-1.02,2.072,,64.69,BAP,-0.873667,0.111618,0.000864022,0.0938601 kka2_1:1_A229L,kka2_1:1_229,Kka2,kka2_1:1,P00552,0.0938822,NO,229,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.739,-3.501,1.762,,0.32,H,A,0.46,-0.7,6.549,,63.64,HHA,-1.851,0.520039,0.00942138,0.0938822 PSD95pdz3_I327D,PSD95pdz3_327,PSD95pdz3,PSD95pdz3,P31016,0.093911,NO,327,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.63,-3.6,1.97,5.7413,,,,,14.0388,,,,PHH,-1.50167,0.0758425,0.000998774,0.093911 beta-lactamase_2500_L192R,beta-lactamase_2500_192,TEM-1,beta-lactamase_2500,P62593,0.0939182,NO,192,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.254,-4.095,2.841,,0.095,H,A,0.55,0.35,1.902,,60.14,HHP,-1.41833,0.361275,0.00558728,0.0939182 beta-lactamase_156_K71M,beta-lactamase_156_71,TEM-1,beta-lactamase_156,P62593,0.0939405,NO,71,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-0.8,-4.48,3.68,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.111618,0.00103192,0.0939405 kka2_1:1_L94I,kka2_1:1_94,Kka2,kka2_1:1,P00552,0.0939456,NO,94,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.618,-2.284,0.666,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.520039,0.00520888,0.0939456 kka2_1:1_Q100N,kka2_1:1_100,Kka2,kka2_1:1,P00552,0.0939456,NO,100,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.77,-3.216,0.446,,0.646,E,B,0.4,-0.79,15.116,15.116,71.59,OPA,-1.46467,0.520039,0.0066405,0.0939456 beta-lactamase_625_V260D,beta-lactamase_625_260,TEM-1,beta-lactamase_625,P62593,0.0939785,NO,260,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.213352,0.00471757,0.0939785 beta-lactamase_39_I125W,beta-lactamase_39_125,TEM-1,beta-lactamase_39,P62593,0.0940399,NO,125,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.441,-5.341,3.9,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.0495842,0.00383964,0.0940399 beta-lactamase_156_G234P,beta-lactamase_156_234,TEM-1,beta-lactamase_156,P62593,0.0940723,NO,234,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.62,-3.88,3.26,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.111618,0.000889577,0.0940723 Pab1_G169T,Pab1_169,Pab1,Pab1,P04147,0.0941103,NO,169,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.809,-3.464,2.655,,,E,b,0.35,0.03,,,,HOH,-1.11567,0.175299,0.000302434,0.0941103 beta-lactamase_2500_L79D,beta-lactamase_2500_79,TEM-1,beta-lactamase_2500,P62593,0.0941187,NO,79,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.842,-4.141,3.299,,0.007,H,A,0.55,-0.16,0.823,,50.35,HHP,-1.44333,0.361275,0.000947397,0.0941187 kka2_1:1_C77Q,kka2_1:1_77,Kka2,kka2_1:1,P00552,0.0941757,NO,77,C,Q,CQ,Special,Polar,5.07,6.24429,1.17429,154,121,146,25,108.5,143.8,35.3,-1.477,-4.277,2.8,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.520039,0.00441216,0.0941757 beta-lactamase_2500_N130W,beta-lactamase_2500_130,TEM-1,beta-lactamase_2500,P62593,0.0943229,NO,130,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-0.798,-5.547,4.749,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.361275,0.000683376,0.0943229 beta-lactamase_39_A246P,beta-lactamase_39_246,TEM-1,beta-lactamase_39,P62593,0.0943643,NO,246,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.121,-4.126,2.005,,0.01,E,B,0.46,-1.01,1.331,,73.78,HHH,-1.55633,0.0495842,0.00569458,0.0943643 beta-lactamase_39_G243P,beta-lactamase_39_243,TEM-1,beta-lactamase_39,P62593,0.0943914,NO,243,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.0495842,0.00464034,0.0943914 beta-lactamase_D129C,beta-lactamase_129,TEM-1,beta-lactamase,P62593,0.0945403,NO,129,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.816,-5.136,4.32,4.84204,,,B,1.33,-0.69,0.548,,34.97,PAP,-0.818,0.221079,0.00109178,0.0945403 beta-lactamase_156_G43R,beta-lactamase_156_43,TEM-1,beta-lactamase_156,P62593,0.0945566,NO,43,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.62,-3.933,3.313,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.111618,0.00120151,0.0945566 beta-lactamase_156_Y95D,beta-lactamase_156_95,TEM-1,beta-lactamase_156,P62593,0.0946627,NO,95,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-1.715,-4.078,2.363,,0.122,,b,0.21,-0.37,2.341,,77.62,BHP,-2.16167,0.111618,0.00479449,0.0946627 beta-lactamase_39_K71V,beta-lactamase_39_71,TEM-1,beta-lactamase_39,P62593,0.0947391,NO,71,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-0.8,-3.529,2.729,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.0495842,0.00103192,0.0947391 kka2_1:1_T225K,kka2_1:1_225,Kka2,kka2_1:1,P00552,0.0947467,NO,225,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.393,-3.78,1.387,,0.036,H,A,0.22,-1.22,4.554,,63.64,HPB,-1.58733,0.520039,0.0113598,0.0947467 beta-lactamase_156_D177F,beta-lactamase_156_177,TEM-1,beta-lactamase_156,P62593,0.0948053,NO,177,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.967,-4.34,3.373,,0.006,T,L,0.75,-1.02,2.072,,64.69,BAP,-0.873667,0.111618,0.000864022,0.0948053 beta-lactamase_I140P,beta-lactamase_140,TEM-1,beta-lactamase,P62593,0.0948458,NO,140,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.733,-4.152,2.419,5.29918,0.128,H,A,1,0.41,1.16,,73.08,PHO,-1.48733,0.221079,0.00597777,0.0948458 kka2_1:1_A71L,kka2_1:1_71,Kka2,kka2_1:1,P00552,0.094922,NO,71,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.824,-3.593,1.769,,0.553,H,A,0.46,0.08,9.788,,64.39,HHP,-1.74033,0.520039,0.00727707,0.094922 beta-lactamase_2500_E164G,beta-lactamase_2500_164,TEM-1,beta-lactamase_2500,P62593,0.0950133,NO,164,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-0.948,-2.443,1.495,,0.011,T,B,1.04,-0.4,0.352,,64.69,HAO,-1.388,0.361275,0.00137286,0.0950133 beta-lactamase_156_D129F,beta-lactamase_156_129,TEM-1,beta-lactamase_156,P62593,0.0950245,NO,129,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.816,-4.318,3.502,,,,B,0.75,-0.69,1.924,,34.97,PAP,-0.818,0.111618,0.00109178,0.0950245 kka2_1:1_V153D,kka2_1:1_153,Kka2,kka2_1:1,P00552,0.0950307,NO,153,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.092,-4.005,2.913,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.520039,0.00501119,0.0950307 kka2_1:2_G233E,kka2_1:2_233,Kka2,kka2_1:2,P00552,0.0951696,NO,233,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.748,-3.501,2.753,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.295029,0.00232366,0.0951696 kka2_1:2_A191K,kka2_1:2_191,Kka2,kka2_1:2,P00552,0.0953362,NO,191,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.831,-3.519,2.688,,,.,b,0.46,-0.94,2.046,,50,AHO,-0.868667,0.295029,0.00338807,0.0953362 beta-lactamase_E164R,beta-lactamase_164,TEM-1,beta-lactamase,P62593,0.095451,NO,164,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-0.948,-3.511,2.563,5.3334,0.011,T,B,1.62,-0.4,1.055,,64.69,HAO,-1.388,0.221079,0.00137286,0.095451 kka2_1:2_L241F,kka2_1:2_241,Kka2,kka2_1:2,P00552,0.0955451,NO,241,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.158,-1.703,0.545,,0.08,H,A,0.55,-0.82,1.598,,63.26,HHH,-1.58533,0.295029,0.0117299,0.0955451 beta-lactamase_2500_N134Q,beta-lactamase_2500_134,TEM-1,beta-lactamase_2500,P62593,0.0956009,NO,134,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-0.879,-3.672,2.793,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.361275,0.000644786,0.0956009 beta-lactamase_W227N,beta-lactamase_227,TEM-1,beta-lactamase,P62593,0.0956252,NO,227,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-0.982,-4.236,3.254,4.86393,0.272,,B,0.99,-0.29,1.37,,74.48,OHH,-1.595,0.221079,0.00226019,0.0956252 kka2_1:2_Q219G,kka2_1:2_219,Kka2,kka2_1:2,P00552,0.0956487,NO,219,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-0.93,-3.41,2.48,,0.088,H,A,0.4,-0.85,1.917,,50,HPA,-1.05167,0.295029,0.00237913,0.0956487 PSD95pdz3_I359D,PSD95pdz3_359,PSD95pdz3,PSD95pdz3,P31016,0.0956559,NO,359,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.63,-3.6,1.97,5.35151,,,,,14.8012,,,,PHH,-1.58667,0.0758425,0.000580694,0.0956559 beta-lactamase_A245Q,beta-lactamase_245,TEM-1,beta-lactamase,P62593,0.0956614,NO,245,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.068,-4.007,2.939,4.78972,,E,B,0.17,-0.92,0.831,,64.69,HHH,-1.58133,0.221079,0.00391032,0.0956614 kka2_1:1_R253W,kka2_1:1_253,Kka2,kka2_1:1,P00552,0.0960226,NO,253,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.356,-5.444,4.088,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.520039,0.0144195,0.0960226 beta-lactamase_156_S128A,beta-lactamase_156_128,TEM-1,beta-lactamase_156,P62593,0.096124,NO,128,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-0.84,-2.628,1.788,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.111618,0.00071483,0.096124 beta-lactamase_156_A185F,beta-lactamase_156_185,TEM-1,beta-lactamase_156,P62593,0.0961256,NO,185,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.406,-4.091,2.685,,,H,A,0.46,-1.02,0.365,,65.03,HHP,-1.84033,0.111618,0.00467449,0.0961256 beta-lactamase_625_K71A,beta-lactamase_625_71,TEM-1,beta-lactamase_625,P62593,0.0961744,NO,71,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-0.8,-3.078,2.278,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.213352,0.00103192,0.0961744 beta-lactamase_2500_G76E,beta-lactamase_2500_76,TEM-1,beta-lactamase_2500,P62593,0.0962268,NO,76,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.189,-3.614,2.425,,,H,A,0.29,-0.67,1.012,,67.83,OOH,-1.22267,0.361275,0.00476637,0.0962268 kka2_1:4_D101I,kka2_1:4_101,Kka2,kka2_1:4,P00552,0.0962561,NO,101,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.028,-3.84,2.812,,0.213,E,B,0.75,-1.24,8.707,,63.64,PAH,-1.534,0.168804,0.00423361,0.0962561 beta-lactamase_L137R,beta-lactamase_137,TEM-1,beta-lactamase,P62593,0.0963513,NO,137,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.03,-4,2.97,5.20117,,H,A,1.07,-0.38,0.674,,42.31,HHP,-1.58933,0.221079,0.00278599,0.0963513 kka2_1:2_V185K,kka2_1:2_185,Kka2,kka2_1:2,P00552,0.0963676,NO,185,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.045,-3.785,2.74,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.295029,0.00367031,0.0963676 beta-lactamase_2500_K71Q,beta-lactamase_2500_71,TEM-1,beta-lactamase_2500,P62593,0.0963716,NO,71,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-0.8,-3.449,2.649,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.361275,0.00103192,0.0963716 kka2_1:4_M116S,kka2_1:4_116,Kka2,kka2_1:4,P00552,0.0965007,NO,116,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-2.482,-3.643,1.161,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.168804,0.00745147,0.0965007 kka2_1:4_L232K,kka2_1:4_232,Kka2,kka2_1:4,P00552,0.0965262,NO,232,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.514,-3.945,2.431,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.168804,0.00800103,0.0965262 beta-lactamase_156_D177K,beta-lactamase_156_177,TEM-1,beta-lactamase_156,P62593,0.0966151,NO,177,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.967,-3.523,2.556,,0.006,T,L,0.75,-1.02,2.072,,64.69,BAP,-0.873667,0.111618,0.000864022,0.0966151 beta-lactamase_2500_G243F,beta-lactamase_2500_243,TEM-1,beta-lactamase_2500,P62593,0.0966617,NO,243,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.361275,0.00464034,0.0966617 Ubiquitin_L8W,Ubiquitin_8,Uba1,Ubiquitin,P0CG48,0.0967742,NO,8,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.723,-5.269,3.546,5.28016,0.664,T,A,0.08,-0.34,0.664,,29.05,PHP,-1.51567,0.205827,0.000726165,0.0967742 kka2_1:1_A78D,kka2_1:1_78,Kka2,kka2_1:1,P00552,0.0968147,NO,78,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.744,-3.601,1.857,,0.078,.,B,0.46,-0.53,0.206,,56.06,OHH,-1.863,0.520039,0.00457299,0.0968147 beta-lactamase_39_P181Y,beta-lactamase_39_181,TEM-1,beta-lactamase_39,P62593,0.0969263,NO,181,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.813,-4.385,3.572,,,H,A,0.52,-1.14,1.946,,61.54,HOH,-1.795,0.0495842,0.000703122,0.0969263 beta-lactamase_625_I244K,beta-lactamase_625_244,TEM-1,beta-lactamase_625,P62593,0.0969654,NO,244,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.555,-3.812,2.257,,,E,B,0.48,-0.84,2.061,,77.62,OHH,-1.385,0.213352,0.00605379,0.0969654 beta-lactamase_2500_P181Y,beta-lactamase_2500_181,TEM-1,beta-lactamase_2500,P62593,0.097005,NO,181,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.813,-4.385,3.572,,,H,A,0.52,-1.14,1.946,,61.54,HOH,-1.795,0.361275,0.000703122,0.097005 kka2_1:8_D82I,kka2_1:8_82,Kka2,kka2_1:8,P00552,0.0970314,NO,82,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.946,-4.04,2.094,,0.341,E,b,0.29,0.52,7.463,,63.64,HAH,-1.98,0.100394,0.00637516,0.0970314 kka2_1:8_D82I,kka2_1:8_82,Kka2,kka2_1:8,P00552,0.0970314,NO,82,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.946,-4.04,2.094,,0.341,E,b,0.29,0.52,7.463,,63.64,HAH,-1.98,0.100394,0.00637516,0.0970314 beta-lactamase_I243G,beta-lactamase_243,TEM-1,beta-lactamase,P62593,0.0971149,NO,243,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.532,-3.58,2.048,5.26886,,E,B,1.68,-1.24,2.289,,50,OHH,-1.46867,0.221079,0.00464034,0.0971149 kka2_1:8_D190Q,kka2_1:8_190,Kka2,kka2_1:8,P00552,0.0971364,NO,190,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.708,-3.703,2.995,,0.213,S,b,0.29,-0.82,,,,OAH,-0.711667,0.100394,0.00247989,0.0971364 kka2_1:8_D190Q,kka2_1:8_190,Kka2,kka2_1:8,P00552,0.0971364,NO,190,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.708,-3.703,2.995,,0.213,S,b,0.29,-0.82,,,,OAH,-0.711667,0.100394,0.00247989,0.0971364 beta-lactamase_C75Q,beta-lactamase_75,TEM-1,beta-lactamase,P62593,0.09722,NO,75,C,Q,CQ,Special,Polar,5.07,6.24429,1.17429,154,121,146,25,108.5,143.8,35.3,-1.245,-4.228,2.983,4.88171,,H,A,0.25,-0.87,0.876,,50,HOO,-1.24333,0.221079,0.0034616,0.09722 beta-lactamase_625_I244R,beta-lactamase_625_244,TEM-1,beta-lactamase_625,P62593,0.0973272,NO,244,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.555,-4.183,2.628,,,E,B,0.48,-0.84,2.061,,77.62,OHH,-1.385,0.213352,0.00605379,0.0973272 beta-lactamase_2500_E35Y,beta-lactamase_2500_35,TEM-1,beta-lactamase_2500,P62593,0.0974105,NO,35,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-0.869,-4.211,3.342,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.361275,0.00174441,0.0974105 kka2_1:8_F263N,kka2_1:8_263,Kka2,kka2_1:8,P00552,0.0975452,NO,263,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-0.911,-4.185,3.274,,0.006,G,A,1.62,-0.12,0.928,,45.83,AHH,-0.92,0.100394,0.0172454,0.0975452 kka2_1:8_F263N,kka2_1:8_263,Kka2,kka2_1:8,P00552,0.0975452,NO,263,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-0.911,-4.185,3.274,,0.006,G,A,1.62,-0.12,0.928,,45.83,AHH,-0.92,0.100394,0.0172454,0.0975452 beta-lactamase_625_V260H,beta-lactamase_625_260,TEM-1,beta-lactamase_625,P62593,0.0976456,NO,260,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.213352,0.00471757,0.0976456 beta-lactamase_L205N,beta-lactamase_205,TEM-1,beta-lactamase,P62593,0.0978464,NO,205,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.922,-4.141,3.219,5.67023,,H,A,1.3,-0.46,0.678,,42.31,PHH,-1.57767,0.221079,0.00255802,0.0978464 kka2_1:2_M197P,kka2_1:2_197,Kka2,kka2_1:2,P00552,0.0978823,NO,197,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.707,-4.141,2.434,,0.121,E,B,0.55,-1.19,2.097,,65.53,HHH,-1.847,0.295029,0.00921295,0.0978823 beta-lactamase_L135D,beta-lactamase_135,TEM-1,beta-lactamase,P62593,0.0979225,NO,135,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.002,-4.125,3.123,5.28497,0.117,H,A,1.07,-0.58,0.697,,43.71,PHH,-1.03767,0.221079,0.00244423,0.0979225 beta-lactamase_156_T69W,beta-lactamase_156_69,TEM-1,beta-lactamase_156,P62593,0.0979605,NO,69,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-0.973,-5.208,4.235,,,G,A,0.22,-1.24,4.194,,93.01,PPH,-1.01833,0.111618,0.00127498,0.0979605 beta-lactamase_S233E,beta-lactamase_233,TEM-1,beta-lactamase,P62593,0.0979844,NO,233,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.886,-3.479,1.593,4.98121,0.016,E,B,0.48,-1.01,5.361,,77.62,BPO,-1.17267,0.221079,0.00311415,0.0979844 beta-lactamase_2500_T107F,beta-lactamase_2500_107,TEM-1,beta-lactamase_2500,P62593,0.0979934,NO,107,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.117,-4.119,3.002,,,G,A,0.22,-0.06,2.686,,67.83,HPA,-1.265,0.361275,0.00239347,0.0979934 kka2_1:4_D190N,kka2_1:4_190,Kka2,kka2_1:4,P00552,0.0980351,NO,190,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.708,-3.251,2.543,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.168804,0.00247989,0.0980351 beta-lactamase_156_D155Y,beta-lactamase_156_155,TEM-1,beta-lactamase_156,P62593,0.0980971,NO,155,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.889,-4.387,3.498,,0.049,,B,0.75,-0.9,0.315,,64.69,OAB,-1.62267,0.111618,0.00135315,0.0980971 beta-lactamase_39_S68R,beta-lactamase_39_68,TEM-1,beta-lactamase_39,P62593,0.0981852,NO,68,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-0.913,-3.705,2.792,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.0495842,0.000800065,0.0981852 beta-lactamase_2500_T69W,beta-lactamase_2500_69,TEM-1,beta-lactamase_2500,P62593,0.0981933,NO,69,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-0.973,-5.208,4.235,,,G,A,0.22,-1.24,2.05,,93.01,PPH,-1.01833,0.361275,0.00127498,0.0981933 beta-lactamase_T107P,beta-lactamase_107,TEM-1,beta-lactamase,P62593,0.0982005,NO,107,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.117,-3.706,2.589,5.23432,,G,A,2.12,-0.06,3.676,,67.83,HPA,-1.265,0.221079,0.00239347,0.0982005 kka2_1:1_Y257K,kka2_1:1_257,Kka2,kka2_1:1,P00552,0.0982849,NO,257,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-1.064,-3.837,2.773,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.520039,0.0148191,0.0982849 kka2_1:1_V75K,kka2_1:1_75,Kka2,kka2_1:1,P00552,0.098369,NO,75,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-2.06,-3.819,1.759,,0.042,.,B,0.44,-0.2,2.815,,71.59,OHO,-1.563,0.520039,0.00693733,0.098369 beta-lactamase_156_L150R,beta-lactamase_156_150,TEM-1,beta-lactamase_156,P62593,0.0983739,NO,150,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.326,-3.982,2.656,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.111618,0.00463171,0.0983739 kka2_1:1_G233Q,kka2_1:1_233,Kka2,kka2_1:1,P00552,0.0984111,NO,233,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.748,-4.098,3.35,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.520039,0.00232366,0.0984111 kka2_1:1_V198N,kka2_1:1_198,Kka2,kka2_1:1,P00552,0.0985397,NO,198,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.719,-3.977,2.258,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.520039,0.00835002,0.0985397 beta-lactamase_156_I244P,beta-lactamase_156_244,TEM-1,beta-lactamase_156,P62593,0.0985561,NO,244,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.555,-4.01,2.455,,,E,B,0.48,-0.84,1.325,,77.62,OHH,-1.385,0.111618,0.00605379,0.0985561 beta-lactamase_0_M127Q,beta-lactamase_0_127,TEM-1,beta-lactamase_0,P62593,0.0985698,NO,127,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-2.251,-2.96,0.709,,0.312,S,A,0.55,0.32,9.35,9.35,72.73,PHP,-1.40433,0.0500837,0.00437927,0.0985698 beta-lactamase_I278Y,beta-lactamase_278,TEM-1,beta-lactamase,P62593,0.0985868,NO,278,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.348,-4.081,2.733,5.35127,0.015,H,A,0.77,-0.85,2.718,,63.29,AHO,-1.41833,0.221079,0.0310297,0.0985868 kka2_1:2_D220Q,kka2_1:2_220,Kka2,kka2_1:2,P00552,0.0987136,NO,220,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.787,-3.763,2.976,,,H,A,0.75,-1.14,0.745,,46.59,PAH,-1.152,0.295029,0.00158066,0.0987136 beta-lactamase_D155G,beta-lactamase_155,TEM-1,beta-lactamase,P62593,0.09877,NO,155,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.889,-3.177,2.288,4.92265,0.049,,B,0.45,-0.9,3.208,,64.69,OAB,-1.62267,0.221079,0.00135315,0.09877 beta-lactamase_2500_G243H,beta-lactamase_2500_243,TEM-1,beta-lactamase_2500,P62593,0.0987709,NO,243,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.361275,0.00464034,0.0987709 kka2_1:4_D220M,kka2_1:4_220,Kka2,kka2_1:4,P00552,0.0988842,NO,220,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.787,-4.844,4.057,,,H,A,0.75,-1.14,1.237,,46.59,PAH,-1.152,0.168804,0.00158066,0.0988842 beta-lactamase_G76D,beta-lactamase_76,TEM-1,beta-lactamase,P62593,0.0989221,NO,76,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.189,-3.614,2.425,4.73862,,H,A,2.05,-0.67,3.059,,67.83,OOH,-1.22267,0.221079,0.00476637,0.0989221 beta-lactamase_G248V,beta-lactamase_248,TEM-1,beta-lactamase,P62593,0.0990099,NO,248,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.794,-2.907,1.113,4.69798,,E,b,0.23,-0.43,1.782,,61.19,HOO,-1.52867,0.221079,0.00428493,0.0990099 beta-lactamase_2500_D177S,beta-lactamase_2500_177,TEM-1,beta-lactamase_2500,P62593,0.0990236,NO,177,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.967,-3.186,2.219,,0.006,T,L,0.75,-1.02,4.131,,64.69,BAP,-0.873667,0.361275,0.000864022,0.0990236 beta-lactamase_2500_E164C,beta-lactamase_2500_164,TEM-1,beta-lactamase_2500,P62593,0.0990295,NO,164,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-0.948,-5.311,4.363,,0.011,T,B,1.04,-0.4,0.352,,64.69,HAO,-1.388,0.361275,0.00137286,0.0990295 kka2_1:1_F240I,kka2_1:1_240,Kka2,kka2_1:1,P00552,0.0992046,NO,240,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-0.911,-3.319,2.408,,,H,A,1.62,-1.21,5.798,,50.38,BHH,-1.67267,0.520039,0.00552543,0.0992046 beta-lactamase_T178W,beta-lactamase_178,TEM-1,beta-lactamase,P62593,0.0992628,NO,178,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-0.791,-5.097,4.306,5.06452,0.029,E,B,0.3,-1.07,,,,APP,-0.947667,0.221079,0.000684366,0.0992628 kka2_1:1_P76I,kka2_1:1_76,Kka2,kka2_1:1,P00552,0.0993627,NO,76,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.449,-3.871,2.422,,0.331,.,B,0.52,-0.41,0.345,,63.64,HOO,-1.662,0.520039,0.00625685,0.0993627 kka2_1:1_I196K,kka2_1:1_196,Kka2,kka2_1:1,P00552,0.099398,NO,196,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-2.115,-3.976,1.861,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.520039,0.0107273,0.099398 beta-lactamase_156_D129M,beta-lactamase_156_129,TEM-1,beta-lactamase_156,P62593,0.0994332,NO,129,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.816,-4.927,4.111,,,,B,0.75,-0.69,1.924,,34.97,PAP,-0.818,0.111618,0.00109178,0.0994332 beta-lactamase_2500_R162W,beta-lactamase_2500_162,TEM-1,beta-lactamase_2500,P62593,0.0994361,NO,162,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.016,-5.367,4.351,,0.124,S,B,1.2,-0.37,6.199,,64.69,ABH,-1.25,0.361275,0.000561334,0.0994361 kka2_1:4_H162E,kka2_1:4_162,Kka2,kka2_1:4,P00552,0.0995433,NO,162,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-2.319,-3.397,1.078,,0.071,G,A,0.17,1.01,3.187,,64.39,ABP,-2.02067,0.168804,0.00616145,0.0995433 beta-lactamase_156_I45P,beta-lactamase_156_45,TEM-1,beta-lactamase_156,P62593,0.099658,NO,45,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-2.421,-4.091,1.67,,,E,B,0.48,-0.3,2.256,,77.62,HHA,-2.30267,0.111618,0.00452842,0.099658 beta-lactamase_156_D177W,beta-lactamase_156_177,TEM-1,beta-lactamase_156,P62593,0.0996789,NO,177,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.967,-5.545,4.578,,0.006,T,L,0.75,-1.02,2.072,,64.69,BAP,-0.873667,0.111618,0.000864022,0.0996789 beta-lactamase_2500_Y44N,beta-lactamase_2500_44,TEM-1,beta-lactamase_2500,P62593,0.0997094,NO,44,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-2.547,-4.162,1.615,,,E,B,0.21,-0.45,2.184,,73.78,OHH,-1.86267,0.361275,0.00426364,0.0997094 beta-lactamase_V31D,beta-lactamase_31,TEM-1,beta-lactamase,P62593,0.0997259,NO,31,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.822,-4.049,2.227,5.43781,,H,A,2.78,-0.46,2.885,,73.78,BHB,-2.03767,0.221079,0.00478065,0.0997259 beta-lactamase_39_T69K,beta-lactamase_39_69,TEM-1,beta-lactamase_39,P62593,0.0998494,NO,69,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-0.973,-3.493,2.52,,,G,A,0.22,-1.24,4.194,,93.01,PPH,-1.01833,0.0495842,0.00127498,0.0998494 kka2_1:4_A224Q,kka2_1:4_224,Kka2,kka2_1:4,P00552,0.0999101,NO,224,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.977,-4.028,3.051,,,H,A,0.46,-1.26,0.93,,63.64,HHP,-1.41033,0.168804,0.00352047,0.0999101 beta-lactamase_625_I245E,beta-lactamase_625_245,TEM-1,beta-lactamase_625,P62593,0.0999245,NO,245,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.213352,0.00391032,0.0999245 beta-lactamase_0_V117W,beta-lactamase_0_117,TEM-1,beta-lactamase_0,P62593,0.0999277,NO,117,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.53,-5.228,3.698,,,H,A,0.44,-0.34,1.16,,65.03,PHB,-1.741,0.0500837,0.00467906,0.0999277 kka2_1:4_G99I,kka2_1:4_99,Kka2,kka2_1:4,P00552,0.0999996,NO,99,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.596,-4.264,3.668,,0.368,S,g,0.29,-0.87,,,,OOP,-1.63067,0.168804,0.00186055,0.0999996 kka2_1:2_L94G,kka2_1:2_94,Kka2,kka2_1:2,P00552,0.100003,NO,94,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.618,-3.801,2.183,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.295029,0.00520888,0.100003 beta-lactamase_2500_L205S,beta-lactamase_2500_205,TEM-1,beta-lactamase_2500,P62593,0.100026,NO,205,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.922,-3.629,2.707,,,H,A,0.55,-0.46,0.831,,42.31,PHH,-1.57767,0.361275,0.00255802,0.100026 beta-lactamase_2500_E35W,beta-lactamase_2500_35,TEM-1,beta-lactamase_2500,P62593,0.100098,NO,35,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-0.869,-5.371,4.502,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.361275,0.00174441,0.100098 beta-lactamase_2500_S128I,beta-lactamase_2500_128,TEM-1,beta-lactamase_2500,P62593,0.100166,NO,128,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-0.84,-3.785,2.945,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.361275,0.00071483,0.100166 kka2_1:1_V185W,kka2_1:1_185,Kka2,kka2_1:1,P00552,0.100191,NO,185,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.045,-5.383,4.338,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.520039,0.00367031,0.100191 beta-lactamase_156_Y44P,beta-lactamase_156_44,TEM-1,beta-lactamase_156,P62593,0.100237,NO,44,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-2.547,-4.12,1.573,,,E,B,0.21,-0.45,2.184,,73.78,OHH,-1.86267,0.111618,0.00426364,0.100237 beta-lactamase_39_Y262R,beta-lactamase_39_262,TEM-1,beta-lactamase_39,P62593,0.100315,NO,262,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.0495842,0.00853516,0.100315 kka2_1:8_I115Y,kka2_1:8_115,Kka2,kka2_1:8,P00552,0.100357,NO,115,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.606,-4.097,2.491,,0.105,H,A,1.52,-1.18,4.064,,65.53,PHH,-2.205,0.100394,0.00836567,0.100357 kka2_1:8_I115Y,kka2_1:8_115,Kka2,kka2_1:8,P00552,0.100357,NO,115,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.606,-4.097,2.491,,0.105,H,A,1.52,-1.18,4.064,,65.53,PHH,-2.205,0.100394,0.00836567,0.100357 beta-lactamase_625_Y262P,beta-lactamase_625_262,TEM-1,beta-lactamase_625,P62593,0.100436,NO,262,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.213352,0.00853516,0.100436 beta-lactamase_2500_D177N,beta-lactamase_2500_177,TEM-1,beta-lactamase_2500,P62593,0.100542,NO,177,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.967,-2.571,1.604,,0.006,T,L,0.75,-1.02,4.131,,64.69,BAP,-0.873667,0.361275,0.000864022,0.100542 beta-lactamase_625_V31R,beta-lactamase_625_31,TEM-1,beta-lactamase_625,P62593,0.100558,NO,31,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.822,-4.173,2.351,,,H,A,0.44,-0.46,2.576,,73.78,BHB,-2.03767,0.213352,0.00478065,0.100558 beta-lactamase_A230N,beta-lactamase_230,TEM-1,beta-lactamase,P62593,0.100561,NO,230,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.154,-3.731,2.577,4.54336,0.01,E,B,0.75,-1.17,1.97,,50,HHA,-1.079,0.221079,0.00516841,0.100561 beta-lactamase_D155F,beta-lactamase_155,TEM-1,beta-lactamase,P62593,0.100561,NO,155,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.889,-4.341,3.452,4.92265,0.049,,B,0.45,-0.9,3.208,,64.69,OAB,-1.62267,0.221079,0.00135315,0.100561 beta-lactamase_D155M,beta-lactamase_155,TEM-1,beta-lactamase,P62593,0.100561,NO,155,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.889,-4.929,4.04,4.92265,0.049,,B,0.45,-0.9,3.208,,64.69,OAB,-1.62267,0.221079,0.00135315,0.100561 kka2_1:1_G95A,kka2_1:1_95,Kka2,kka2_1:1,P00552,0.100562,NO,95,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-2.403,-3.101,0.698,,0.126,E,B,0.29,-0.74,7.822,,71.59,HOA,-2.198,0.520039,0.00743616,0.100562 kka2_1:1_M116W,kka2_1:1_116,Kka2,kka2_1:1,P00552,0.100583,NO,116,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-2.482,-5.227,2.745,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.520039,0.00745147,0.100583 beta-lactamase_625_G43K,beta-lactamase_625_43,TEM-1,beta-lactamase_625,P62593,0.100675,NO,43,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.62,-3.682,3.062,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.213352,0.00120151,0.100675 beta-lactamase_625_L248H,beta-lactamase_625_248,TEM-1,beta-lactamase_625,P62593,0.100744,NO,248,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.213352,0.00428493,0.100744 kka2_1:2_V198W,kka2_1:2_198,Kka2,kka2_1:2,P00552,0.100829,NO,198,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.719,-5.441,3.722,,0.05,E,B,1.48,-0.95,1.074,,56.06,HHA,-1.88667,0.295029,0.00835002,0.100829 beta-lactamase_625_I258K,beta-lactamase_625_258,TEM-1,beta-lactamase_625,P62593,0.100853,NO,258,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.213352,0.007931,0.100853 kka2_1:2_R226F,kka2_1:2_226,Kka2,kka2_1:2,P00552,0.100953,NO,226,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.392,-4.163,2.771,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.295029,0.0108032,0.100953 beta-lactamase_2500_L188E,beta-lactamase_2500_188,TEM-1,beta-lactamase_2500,P62593,0.100979,NO,188,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.166,-2.834,1.668,,,H,A,0.55,-0.3,17.865,17.865,60.14,PHB,-1.47033,0.361275,0.00295687,0.100979 beta-lactamase_T107H,beta-lactamase_107,TEM-1,beta-lactamase,P62593,0.100979,NO,107,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.117,-4.67,3.553,5.23432,,G,A,2.12,-0.06,3.676,,67.83,HPA,-1.265,0.221079,0.00239347,0.100979 beta-lactamase_156_A185K,beta-lactamase_156_185,TEM-1,beta-lactamase_156,P62593,0.10098,NO,185,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.406,-3.666,2.26,,,H,A,0.46,-1.02,0.365,,65.03,HHP,-1.84033,0.111618,0.00467449,0.10098 Pab1_S154H,Pab1_154,Pab1,Pab1,P04147,0.101,NO,154,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.146,-4.272,3.126,,0.208,E,B,0.1,-0.75,,,,HPP,-1.408,0.175299,0.000319331,0.101 beta-lactamase_156_S233D,beta-lactamase_156_233,TEM-1,beta-lactamase_156,P62593,0.101029,NO,233,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.886,-3.5,1.614,,0.016,E,B,0.27,-1.01,4.111,,77.62,BPO,-1.17267,0.111618,0.00311415,0.101029 kka2_1:2_I221R,kka2_1:2_221,Kka2,kka2_1:2,P00552,0.101102,NO,221,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.739,-4.17,2.431,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.295029,0.00945908,0.101102 kka2_1:4_F256G,kka2_1:4_256,Kka2,kka2_1:4,P00552,0.101111,NO,256,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.49,-3.713,2.223,,,H,A,0.58,-0.78,1.653,,53.03,HHH,-1.423,0.168804,0.0132841,0.101111 beta-lactamase_2500_V260R,beta-lactamase_2500_260,TEM-1,beta-lactamase_2500,P62593,0.10117,NO,260,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.361275,0.00471757,0.10117 beta-lactamase_156_Y262R,beta-lactamase_156_262,TEM-1,beta-lactamase_156,P62593,0.1012,NO,262,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.111618,0.00853516,0.1012 kka2_1:2_L212W,kka2_1:2_212,Kka2,kka2_1:2,P00552,0.101248,NO,212,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.904,-5.226,4.322,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.295029,0.0031426,0.101248 beta-lactamase_2500_D177L,beta-lactamase_2500_177,TEM-1,beta-lactamase_2500,P62593,0.101329,NO,177,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.967,-3.772,2.805,,0.006,T,L,0.75,-1.02,4.131,,64.69,BAP,-0.873667,0.361275,0.000864022,0.101329 beta-lactamase_625_L137K,beta-lactamase_625_137,TEM-1,beta-lactamase_625,P62593,0.101519,NO,137,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.03,-3.749,2.719,,,H,A,0.55,-0.38,1.5,,42.31,HHP,-1.58933,0.213352,0.00278599,0.101519 beta-lactamase_625_I245P,beta-lactamase_625_245,TEM-1,beta-lactamase_625,P62593,0.101539,NO,245,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.213352,0.00391032,0.101539 kka2_1:4_A144L,kka2_1:4_144,Kka2,kka2_1:4,P00552,0.101561,NO,144,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.859,-3.107,2.248,,,H,A,0.46,0.21,6.844,,52.65,BHB,-1.72933,0.168804,0.00231095,0.101561 kka2_1:4_F240W,kka2_1:4_240,Kka2,kka2_1:4,P00552,0.101664,NO,240,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-0.911,-4.558,3.647,,,H,A,0.58,-1.21,5.798,,50.38,BHH,-1.67267,0.168804,0.00552543,0.101664 beta-lactamase_A245N,beta-lactamase_245,TEM-1,beta-lactamase,P62593,0.101793,NO,245,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.068,-3.814,2.746,4.78972,,E,B,0.17,-0.92,0.831,,64.69,HHH,-1.58133,0.221079,0.00391032,0.101793 beta-lactamase_2500_L167K,beta-lactamase_2500_167,TEM-1,beta-lactamase_2500,P62593,0.101794,NO,167,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.138,-3.594,2.456,,0.015,G,A,0.55,-0.63,7.813,,64.69,AHP,-1.30767,0.361275,0.00303566,0.101794 kka2_1:8_R217Y,kka2_1:8_217,Kka2,kka2_1:8,P00552,0.10188,NO,217,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.158,-4.252,3.094,,0.252,T,A,0.16,-0.59,1.151,,52.27,ABH,-1.127,0.100394,0.0047191,0.10188 kka2_1:8_R217Y,kka2_1:8_217,Kka2,kka2_1:8,P00552,0.10188,NO,217,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.158,-4.252,3.094,,0.252,T,A,0.16,-0.59,1.151,,52.27,ABH,-1.127,0.100394,0.0047191,0.10188 kka2_1:8_V214P,kka2_1:8_214,Kka2,kka2_1:8,P00552,0.10188,NO,214,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.261,-4.14,2.879,,0.117,E,B,1.48,-0.31,1.859,,64.39,OHH,-0.941667,0.100394,0.00692782,0.10188 kka2_1:8_V214P,kka2_1:8_214,Kka2,kka2_1:8,P00552,0.10188,NO,214,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.261,-4.14,2.879,,0.117,E,B,1.48,-0.31,1.859,,64.39,OHH,-0.941667,0.100394,0.00692782,0.10188 beta-lactamase_156_R257P,beta-lactamase_156_257,TEM-1,beta-lactamase_156,P62593,0.101884,NO,257,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.111618,0.00756629,0.101884 kka2_1:1_W15F,kka2_1:1_15,Kka2,kka2_1:1,P00552,0.101901,NO,15,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-1.392,-2.518,1.126,,0.01,G,A,0.47,0.15,20.149,20.149,52.27,HHH,-2.10533,0.520039,0.00585505,0.101901 beta-lactamase_2500_P181H,beta-lactamase_2500_181,TEM-1,beta-lactamase_2500,P62593,0.101907,NO,181,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.813,-4.706,3.893,,,H,A,0.52,-1.14,1.946,,61.54,HOH,-1.795,0.361275,0.000703122,0.101907 beta-lactamase_N130M,beta-lactamase_130,TEM-1,beta-lactamase,P62593,0.101919,NO,130,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-0.798,-4.705,3.907,5.26686,0.069,H,A,1.08,-0.74,,,,APP,-0.980667,0.221079,0.000683376,0.101919 beta-lactamase_2500_P65C,beta-lactamase_2500_65,TEM-1,beta-lactamase_2500,P62593,0.102057,NO,65,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.894,-5.01,4.116,,0.098,E,B,0.52,-0.62,0.3,,40.56,HOH,-1.03233,0.361275,0.00152776,0.102057 kka2_1:4_L223G,kka2_1:4_223,Kka2,kka2_1:4,P00552,0.102098,NO,223,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.861,-3.881,3.02,,,H,A,1.59,-1.24,1.268,,50,HHH,-0.854333,0.168804,0.00253574,0.102098 beta-lactamase_2500_T69K,beta-lactamase_2500_69,TEM-1,beta-lactamase_2500,P62593,0.102122,NO,69,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-0.973,-3.493,2.52,,,G,A,0.22,-1.24,2.05,,93.01,PPH,-1.01833,0.361275,0.00127498,0.102122 beta-lactamase_625_L205G,beta-lactamase_625_205,TEM-1,beta-lactamase_625,P62593,0.102258,NO,205,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.922,-3.783,2.861,,,H,A,0.55,-0.46,3.782,,42.31,PHH,-1.57767,0.213352,0.00255802,0.102258 kka2_1:1_H135S,kka2_1:1_135,Kka2,kka2_1:1,P00552,0.102282,NO,135,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-1.331,-3.439,2.108,,0.071,.,a,0.17,0.65,3.574,,53.03,ABP,-1.77367,0.520039,0.00532566,0.102282 beta-lactamase_T179L,beta-lactamase_179,TEM-1,beta-lactamase,P62593,0.102303,NO,179,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.085,-3.263,2.178,5.07116,,E,B,0.8,-1.38,1.859,,73.08,PPH,-1.557,0.221079,0.00226045,0.102303 beta-lactamase_39_E164A,beta-lactamase_39_164,TEM-1,beta-lactamase_39,P62593,0.102344,NO,164,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-0.948,-3.102,2.154,,0.011,T,B,1.04,-0.4,0.664,,64.69,HAO,-1.388,0.0495842,0.00137286,0.102344 kka2_1:2_D190K,kka2_1:2_190,Kka2,kka2_1:2,P00552,0.102428,NO,190,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.708,-3.485,2.777,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.295029,0.00247989,0.102428 beta-lactamase_2500_N130I,beta-lactamase_2500_130,TEM-1,beta-lactamase_2500,P62593,0.102483,NO,130,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-0.798,-4.01,3.212,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.361275,0.000683376,0.102483 kka2_1:2_F206D,kka2_1:2_206,Kka2,kka2_1:2,P00552,0.102542,NO,206,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.349,-4.082,2.733,,0.006,E,B,0.58,-1.21,0.978,,63.64,OHH,-1.04,0.295029,0.00936868,0.102542 beta-lactamase_D177R,beta-lactamase_177,TEM-1,beta-lactamase,P62593,0.102647,NO,177,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.967,-3.931,2.964,5.08038,0.006,T,L,1.59,-1.02,3.536,,64.69,BAP,-0.873667,0.221079,0.000864022,0.102647 PSD95pdz3_I388R,PSD95pdz3_388,PSD95pdz3,PSD95pdz3,P31016,0.102698,NO,388,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.63,-3.84,2.21,5.17282,,,,,16.0025,,,,PHH,-1.54967,0.0758425,0.000151216,0.102698 beta-lactamase_156_I258H,beta-lactamase_156_258,TEM-1,beta-lactamase_156,P62593,0.102871,NO,258,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.111618,0.007931,0.102871 kka2_1:8_Y257K,kka2_1:8_257,Kka2,kka2_1:8,P00552,0.102892,NO,257,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-1.064,-3.837,2.773,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.100394,0.0148191,0.102892 kka2_1:8_Y257K,kka2_1:8_257,Kka2,kka2_1:8,P00552,0.102892,NO,257,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-1.064,-3.837,2.773,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.100394,0.0148191,0.102892 kka2_1:1_G210A,kka2_1:1_210,Kka2,kka2_1:1,P00552,0.10292,NO,210,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.095,-2.003,0.908,,0.103,T,A,0.29,-0.62,14.483,14.483,50,OOB,-0.966667,0.520039,0.00598378,0.10292 beta-lactamase_156_I245P,beta-lactamase_156_245,TEM-1,beta-lactamase_156,P62593,0.102944,NO,245,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.111618,0.00391032,0.102944 beta-lactamase_2500_I229K,beta-lactamase_2500_229,TEM-1,beta-lactamase_2500,P62593,0.103053,NO,229,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.267,-3.862,2.595,,0.083,E,B,0.48,-0.76,3.875,,50,HHH,-1.58767,0.361275,0.00477249,0.103053 beta-lactamase_K232A,beta-lactamase_232,TEM-1,beta-lactamase,P62593,0.103076,NO,232,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.012,-3.12,2.108,5.18286,,E,B,2.92,-1.1,1.174,,65.03,ABP,-1.238,0.221079,0.00313441,0.103076 beta-lactamase_2500_M184P,beta-lactamase_2500_184,TEM-1,beta-lactamase_2500,P62593,0.103081,NO,184,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.593,-4.009,2.416,,,H,A,0.55,-0.87,2.893,,62.94,HHH,-1.41,0.361275,0.00356019,0.103081 beta-lactamase_625_L136K,beta-lactamase_625_136,TEM-1,beta-lactamase_625,P62593,0.103112,NO,136,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.232,-3.824,2.592,,,H,A,0.55,-0.34,0.336,,48.95,HHH,-1.088,0.213352,0.00442304,0.103112 kka2_1:8_V113N,kka2_1:8_113,Kka2,kka2_1:8,P00552,0.103144,NO,113,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.233,-4.251,3.018,,0.008,H,A,1.48,-1.17,1.254,,52.27,BHP,-2.08367,0.100394,0.00650191,0.103144 kka2_1:8_V113N,kka2_1:8_113,Kka2,kka2_1:8,P00552,0.103144,NO,113,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.233,-4.251,3.018,,0.008,H,A,1.48,-1.17,1.254,,52.27,BHP,-2.08367,0.100394,0.00650191,0.103144 kka2_1:1_I207R,kka2_1:1_207,Kka2,kka2_1:1,P00552,0.103161,NO,207,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.175,-4.245,3.07,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.520039,0.00611824,0.103161 beta-lactamase_2500_M66N,beta-lactamase_2500_66,TEM-1,beta-lactamase_2500,P62593,0.103171,NO,66,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.362,-4.083,2.721,,0.013,,A,0.55,-0.7,0.502,,73.08,OHH,-1.49567,0.361275,0.00412876,0.103171 beta-lactamase_Y44D,beta-lactamase_44,TEM-1,beta-lactamase,P62593,0.103385,NO,44,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-2.547,-4.061,1.514,5.6273,,E,B,2.55,-0.45,2.683,,73.78,OHH,-1.86267,0.221079,0.00426364,0.103385 beta-lactamase_2500_G52I,beta-lactamase_2500_52,TEM-1,beta-lactamase_2500,P62593,0.103462,NO,52,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.149,-4.163,3.014,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.361275,0.00340138,0.103462 beta-lactamase_39_E164T,beta-lactamase_39_164,TEM-1,beta-lactamase_39,P62593,0.103477,NO,164,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-0.948,-3.491,2.543,,0.011,T,B,1.04,-0.4,0.664,,64.69,HAO,-1.388,0.0495842,0.00137286,0.103477 beta-lactamase_39_I229P,beta-lactamase_39_229,TEM-1,beta-lactamase_39,P62593,0.103507,NO,229,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.267,-4.079,2.812,,0.083,E,B,0.48,-0.76,1.114,,50,HHH,-1.58767,0.0495842,0.00477249,0.103507 beta-lactamase_39_P181Q,beta-lactamase_39_181,TEM-1,beta-lactamase_39,P62593,0.103601,NO,181,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.813,-3.925,3.112,,,H,A,0.52,-1.14,1.946,,61.54,HOH,-1.795,0.0495842,0.000703122,0.103601 kka2_1:1_Y257N,kka2_1:1_257,Kka2,kka2_1:1,P00552,0.103604,NO,257,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-1.064,-4.053,2.989,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.520039,0.0148191,0.103604 beta-lactamase_C75E,beta-lactamase_75,TEM-1,beta-lactamase,P62593,0.103664,NO,75,C,E,CE,Special,negativeCharge,5.07,3.22,-1.85,170,121,147,26,108.5,138.4,29.9,-1.245,-3.874,2.629,4.88171,,H,A,0.25,-0.87,0.876,,50,HOO,-1.24333,0.221079,0.0034616,0.103664 beta-lactamase_D177L,beta-lactamase_177,TEM-1,beta-lactamase,P62593,0.103664,NO,177,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.967,-3.772,2.805,5.08038,0.006,T,L,1.59,-1.02,3.536,,64.69,BAP,-0.873667,0.221079,0.000864022,0.103664 beta-lactamase_R255W,beta-lactamase_255,TEM-1,beta-lactamase,P62593,0.103664,NO,255,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.266,-3.331,1.065,5.55882,0.141,E,B,0.68,0.38,1.199,,63.99,PBH,-2.00433,0.221079,0.00499612,0.103664 beta-lactamase_39_S128H,beta-lactamase_39_128,TEM-1,beta-lactamase_39,P62593,0.103709,NO,128,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-0.84,-4.455,3.615,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.0495842,0.00071483,0.103709 beta-lactamase_156_L205R,beta-lactamase_156_205,TEM-1,beta-lactamase_156,P62593,0.103743,NO,205,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.922,-3.987,3.065,,,H,A,0.55,-0.46,0.678,,42.31,PHH,-1.57767,0.111618,0.00255802,0.103743 beta-lactamase_2500_T131Q,beta-lactamase_2500_131,TEM-1,beta-lactamase_2500,P62593,0.103874,NO,131,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.328,-3.951,2.623,,,H,A,0.22,-0.69,3.048,,67.48,PPH,-1.00867,0.361275,0.00345886,0.103874 beta-lactamase_625_T69Q,beta-lactamase_625_69,TEM-1,beta-lactamase_625,P62593,0.103899,NO,69,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-0.973,-3.935,2.962,,,G,A,0.22,-1.24,2.716,,93.01,PPH,-1.01833,0.213352,0.00127498,0.103899 beta-lactamase_2500_Y44P,beta-lactamase_2500_44,TEM-1,beta-lactamase_2500,P62593,0.103916,NO,44,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-2.547,-4.12,1.573,,,E,B,0.21,-0.45,2.184,,73.78,OHH,-1.86267,0.361275,0.00426364,0.103916 beta-lactamase_2500_S128P,beta-lactamase_2500_128,TEM-1,beta-lactamase_2500,P62593,0.103993,NO,128,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-0.84,-3.655,2.815,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.361275,0.00071483,0.103993 beta-lactamase_625_L137R,beta-lactamase_625_137,TEM-1,beta-lactamase_625,P62593,0.104071,NO,137,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.03,-4,2.97,,,H,A,0.55,-0.38,1.5,,42.31,HHP,-1.58933,0.213352,0.00278599,0.104071 beta-lactamase_625_D177G,beta-lactamase_625_177,TEM-1,beta-lactamase_625,P62593,0.104081,NO,177,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.967,-2.392,1.425,,0.006,T,L,0.75,-1.02,1.333,,64.69,BAP,-0.873667,0.213352,0.000864022,0.104081 beta-lactamase_625_K71W,beta-lactamase_625_71,TEM-1,beta-lactamase_625,P62593,0.104124,NO,71,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-0.8,-5.322,4.522,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.213352,0.00103192,0.104124 kka2_1:4_V214D,kka2_1:4_214,Kka2,kka2_1:4,P00552,0.104176,NO,214,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.261,-4.099,2.838,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.168804,0.00692782,0.104176 Pab1_N127V,Pab1_127,Pab1,Pab1,P04147,0.104232,NO,127,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-1.079,-3.571,2.492,,0.138,E,B,1.05,-0.51,,,,OPH,-1.13633,0.175299,0.000805159,0.104232 kka2_1:4_I207P,kka2_1:4_207,Kka2,kka2_1:4,P00552,0.104295,NO,207,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.175,-4.149,2.974,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.168804,0.00611824,0.104295 kka2_1:4_G245H,kka2_1:4_245,Kka2,kka2_1:4,P00552,0.104336,NO,245,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.812,-4.652,3.84,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.168804,0.00683899,0.104336 beta-lactamase_2500_N130L,beta-lactamase_2500_130,TEM-1,beta-lactamase_2500,P62593,0.104352,NO,130,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-0.798,-3.583,2.785,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.361275,0.000683376,0.104352 beta-lactamase_2500_G43M,beta-lactamase_2500_43,TEM-1,beta-lactamase_2500,P62593,0.104389,NO,43,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.62,-4.93,4.31,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.361275,0.00120151,0.104389 beta-lactamase_39_K232H,beta-lactamase_39_232,TEM-1,beta-lactamase_39,P62593,0.104501,NO,232,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.012,-4.433,3.421,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.0495842,0.00313441,0.104501 kka2_1:2_N200Y,kka2_1:2_200,Kka2,kka2_1:2,P00552,0.10463,NO,200,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-2.446,-4.44,1.994,,0.756,T,L,0.61,-0.08,2.836,,64.39,APO,-2.08,0.295029,0.00838549,0.10463 beta-lactamase_625_G142F,beta-lactamase_625_142,TEM-1,beta-lactamase_625,P62593,0.104684,NO,142,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.707,-4.29,3.583,,0.034,,p,0.29,-0.64,1.35,,64.69,OOO,-0.834,0.213352,0.00060149,0.104684 beta-lactamase_2500_Y44R,beta-lactamase_2500_44,TEM-1,beta-lactamase_2500,P62593,0.104692,NO,44,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-2.547,-4.123,1.576,,,E,B,0.21,-0.45,2.184,,73.78,OHH,-1.86267,0.361275,0.00426364,0.104692 beta-lactamase_2500_Y44G,beta-lactamase_2500_44,TEM-1,beta-lactamase_2500,P62593,0.104706,NO,44,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-2.547,-3.687,1.14,,,E,B,0.21,-0.45,2.184,,73.78,OHH,-1.86267,0.361275,0.00426364,0.104706 beta-lactamase_2500_L136E,beta-lactamase_2500_136,TEM-1,beta-lactamase_2500,P62593,0.10472,NO,136,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.232,-3.938,2.706,,,H,A,0.55,-0.34,1.36,,48.95,HHH,-1.088,0.361275,0.00442304,0.10472 beta-lactamase_D155P,beta-lactamase_155,TEM-1,beta-lactamase,P62593,0.104738,NO,155,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.889,-3.725,2.836,4.92265,0.049,,B,0.45,-0.9,3.208,,64.69,OAB,-1.62267,0.221079,0.00135315,0.104738 beta-lactamase_L73K,beta-lactamase_73,TEM-1,beta-lactamase,P62593,0.104738,NO,73,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.507,-3.846,2.339,5.84139,,H,A,1.75,-0.64,2.09,,67.83,HHH,-1.487,0.221079,0.00488983,0.104738 kka2_1:4_P194H,kka2_1:4_194,Kka2,kka2_1:4,P00552,0.104781,NO,194,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.846,-4.708,3.862,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.168804,0.00314194,0.104781 kka2_1:2_G245H,kka2_1:2_245,Kka2,kka2_1:2,P00552,0.104825,NO,245,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.812,-4.652,3.84,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.295029,0.00683899,0.104825 Ubiquitin_V5D,Ubiquitin_5,Uba1,Ubiquitin,P0CG48,0.104839,NO,5,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.576,-2.712,1.136,4.75677,,E,B,,-0.82,,,,HHB,-1.401,0.205827,0.000796998,0.104839 beta-lactamase_39_K71W,beta-lactamase_39_71,TEM-1,beta-lactamase_39,P62593,0.104994,NO,71,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-0.8,-5.322,4.522,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.0495842,0.00103192,0.104994 beta-lactamase_2500_V78Y,beta-lactamase_2500_78,TEM-1,beta-lactamase_2500,P62593,0.105003,NO,78,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.459,-4.112,2.653,,,H,A,0.44,-0.47,31.376,31.376,63.64,HHH,-1.17833,0.361275,0.00492501,0.105003 beta-lactamase_39_S128C,beta-lactamase_39_128,TEM-1,beta-lactamase_39,P62593,0.105052,NO,128,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-0.84,-4.637,3.797,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.0495842,0.00071483,0.105052 beta-lactamase_156_L47P,beta-lactamase_156_47,TEM-1,beta-lactamase_156,P62593,0.105084,NO,47,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.876,-4.153,2.277,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.111618,0.00439844,0.105084 beta-lactamase_2500_L79Y,beta-lactamase_2500_79,TEM-1,beta-lactamase_2500,P62593,0.105113,NO,79,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.842,-3.963,3.121,,0.007,H,A,0.55,-0.16,0.823,,50.35,HHP,-1.44333,0.361275,0.000947397,0.105113 kka2_1:4_N200P,kka2_1:4_200,Kka2,kka2_1:4,P00552,0.105154,NO,200,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-2.446,-4.046,1.6,,0.756,T,L,0.61,-0.08,1.746,,64.39,APO,-2.08,0.168804,0.00838549,0.105154 kka2_1:4_A144Q,kka2_1:4_144,Kka2,kka2_1:4,P00552,0.105312,NO,144,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.859,-4.01,3.151,,,H,A,0.46,0.21,6.844,,52.65,BHB,-1.72933,0.168804,0.00231095,0.105312 beta-lactamase_156_L74H,beta-lactamase_156_74,TEM-1,beta-lactamase_156,P62593,0.105314,NO,74,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.296,-4.896,3.6,,,H,A,0.55,-0.91,0.746,,50,HHO,-1.34933,0.111618,0.00493255,0.105314 beta-lactamase_156_V260R,beta-lactamase_156_260,TEM-1,beta-lactamase_156,P62593,0.105343,NO,260,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.111618,0.00471757,0.105343 kka2_1:4_L260S,kka2_1:4_260,Kka2,kka2_1:4,P00552,0.105359,NO,260,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.741,-3.639,2.898,,0.022,H,A,0.55,-0.52,,,,HHA,-0.845667,0.168804,0.0233782,0.105359 beta-lactamase_2500_F64E,beta-lactamase_2500_64,TEM-1,beta-lactamase_2500,P62593,0.105523,NO,64,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-0.841,-3.89,3.049,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.361275,0.000947691,0.105523 beta-lactamase_I275G,beta-lactamase_275,TEM-1,beta-lactamase,P62593,0.105612,NO,275,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.397,-3.822,2.425,5.3999,0.015,H,A,1,-0.52,0.836,,62.59,PHH,-1.541,0.221079,0.0141984,0.105612 kka2_1:4_D208R,kka2_1:4_208,Kka2,kka2_1:4,P00552,0.105615,NO,208,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.708,-3.961,3.253,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.168804,0.00212588,0.105615 beta-lactamase_2500_P143W,beta-lactamase_2500_143,TEM-1,beta-lactamase_2500,P62593,0.10564,NO,143,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.967,-5.497,4.53,,0.075,H,A,0.52,-0.37,0.479,,66.78,OOB,-1.354,0.361275,0.00114551,0.10564 kka2_1:4_I196P,kka2_1:4_196,Kka2,kka2_1:4,P00552,0.105702,NO,196,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-2.115,-4.338,2.223,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.168804,0.0107273,0.105702 beta-lactamase_L160R,beta-lactamase_160,TEM-1,beta-lactamase,P62593,0.105839,NO,160,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.977,-4.03,3.053,5.32068,0.022,,B,1.75,-0.6,0.895,,44.41,BHA,-0.936,0.221079,0.00193775,0.105839 beta-lactamase_625_T178Y,beta-lactamase_625_178,TEM-1,beta-lactamase_625,P62593,0.105873,NO,178,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-0.791,-4.162,3.371,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.213352,0.000684366,0.105873 kka2_1:8_R226Y,kka2_1:8_226,Kka2,kka2_1:8,P00552,0.105908,NO,226,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.392,-3.976,2.584,,0.222,H,A,0.16,-0.71,3.818,,56.06,PBA,-1.84767,0.100394,0.0108032,0.105908 kka2_1:8_R226Y,kka2_1:8_226,Kka2,kka2_1:8,P00552,0.105908,NO,226,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.392,-3.976,2.584,,0.222,H,A,0.16,-0.71,3.818,,56.06,PBA,-1.84767,0.100394,0.0108032,0.105908 beta-lactamase_T107R,beta-lactamase_107,TEM-1,beta-lactamase,P62593,0.105991,NO,107,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.117,-3.76,2.643,5.23432,,G,A,2.12,-0.06,3.676,,67.83,HPA,-1.265,0.221079,0.00239347,0.105991 beta-lactamase_2500_V31G,beta-lactamase_2500_31,TEM-1,beta-lactamase_2500,P62593,0.10624,NO,31,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.822,-3.699,1.877,,,H,A,0.44,-0.46,0.955,,73.78,BHB,-2.03767,0.361275,0.00478065,0.10624 beta-lactamase_625_A124E,beta-lactamase_625_124,TEM-1,beta-lactamase_625,P62593,0.106292,NO,124,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.181,-3.544,2.363,,,H,A,0.46,-0.9,2.027,,64.34,HHH,-1.152,0.213352,0.00481399,0.106292 beta-lactamase_625_M67K,beta-lactamase_625_67,TEM-1,beta-lactamase_625,P62593,0.106362,NO,67,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-2.231,-3.7,1.469,,0.006,G,P,0.55,-0.81,2.653,,65.03,HHP,-1.502,0.213352,0.00409753,0.106362 beta-lactamase_625_G43Y,beta-lactamase_625_43,TEM-1,beta-lactamase_625,P62593,0.106407,NO,43,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.62,-4.387,3.767,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.213352,0.00120151,0.106407 beta-lactamase_2500_I277P,beta-lactamase_2500_277,TEM-1,beta-lactamase_2500,P62593,0.106425,NO,277,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.361275,0.0169305,0.106425 beta-lactamase_2500_G243M,beta-lactamase_2500_243,TEM-1,beta-lactamase_2500,P62593,0.106502,NO,243,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.361275,0.00464034,0.106502 beta-lactamase_2500_D129P,beta-lactamase_2500_129,TEM-1,beta-lactamase_2500,P62593,0.106582,NO,129,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.816,-3.68,2.864,,,,B,0.75,-0.69,1.29,,34.97,PAP,-0.818,0.361275,0.00109178,0.106582 beta-lactamase_2500_E164S,beta-lactamase_2500_164,TEM-1,beta-lactamase_2500,P62593,0.106612,NO,164,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-0.948,-3.21,2.262,,0.011,T,B,1.04,-0.4,0.352,,64.69,HAO,-1.388,0.361275,0.00137286,0.106612 kka2_1:8_A117N,kka2_1:8_117,Kka2,kka2_1:8,P00552,0.106658,NO,117,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.828,-3.99,3.162,,,H,A,1.04,-0.78,0.755,,45.83,HHA,-1.79333,0.100394,0.00282984,0.106658 kka2_1:8_A117N,kka2_1:8_117,Kka2,kka2_1:8,P00552,0.106658,NO,117,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.828,-3.99,3.162,,,H,A,1.04,-0.78,0.755,,45.83,HHA,-1.79333,0.100394,0.00282984,0.106658 kka2_1:1_A34W,kka2_1:1_34,Kka2,kka2_1:1,P00552,0.106667,NO,34,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.928,-5.383,4.455,,0.417,.,B,0.46,2.29,0.262,,52.27,AHH,-1.747,0.520039,0.00343484,0.106667 kka2_1:1_F264M,kka2_1:1_264,Kka2,kka2_1:1,P00552,0.106746,NO,264,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.02,-4.352,3.332,,0.296,.,?,0.58,0.02,2.303,,71.59,HHNA,-0.9655,0.520039,,0.106746 beta-lactamase_2500_V78W,beta-lactamase_2500_78,TEM-1,beta-lactamase_2500,P62593,0.106772,NO,78,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.459,-5.345,3.886,,,H,A,0.44,-0.47,31.376,31.376,63.64,HHH,-1.17833,0.361275,0.00492501,0.106772 kka2_1:4_F133D,kka2_1:4_133,Kka2,kka2_1:4,P00552,0.106842,NO,133,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-0.871,-3.97,3.099,,0.178,.,B,0.58,0.43,0.786,,42.42,OHA,-0.871667,0.168804,0.00182168,0.106842 kka2_1:2_G88Y,kka2_1:2_88,Kka2,kka2_1:2,P00552,0.106948,NO,88,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.689,-4.408,2.719,,0.54,S,l,0.75,1.51,2.814,,65.53,HOB,-1.718,0.295029,0.00685559,0.106948 beta-lactamase_M1R,beta-lactamase_1,TEM-1,beta-lactamase,P62593,0.106949,NO,1,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.998,-3.39,1.392,,,,,,,,,,OHP,-1.97,0.221079,0.00162771,0.106949 beta-lactamase_Y44S,beta-lactamase_44,TEM-1,beta-lactamase,P62593,0.106949,NO,44,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-2.547,-3.605,1.058,5.6273,,E,B,2.55,-0.45,2.683,,73.78,OHH,-1.86267,0.221079,0.00426364,0.106949 beta-lactamase_2500_K71T,beta-lactamase_2500_71,TEM-1,beta-lactamase_2500,P62593,0.106979,NO,71,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-0.8,-3.421,2.621,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.361275,0.00103192,0.106979 beta-lactamase_156_D129K,beta-lactamase_156_129,TEM-1,beta-lactamase_156,P62593,0.107149,NO,129,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.816,-3.42,2.604,,,,B,0.75,-0.69,1.924,,34.97,PAP,-0.818,0.111618,0.00109178,0.107149 beta-lactamase_T107E,beta-lactamase_107,TEM-1,beta-lactamase,P62593,0.107154,NO,107,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.117,-3.43,2.313,5.23432,,G,A,2.12,-0.06,3.676,,67.83,HPA,-1.265,0.221079,0.00239347,0.107154 kka2_1:2_E63H,kka2_1:2_63,Kka2,kka2_1:2,P00552,0.107159,NO,63,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-0.762,-4.258,3.496,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.295029,0.00118399,0.107159 kka2_1:4_V198D,kka2_1:4_198,Kka2,kka2_1:4,P00552,0.107165,NO,198,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.719,-3.799,2.08,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.168804,0.00835002,0.107165 beta-lactamase_39_K232D,beta-lactamase_39_232,TEM-1,beta-lactamase_39,P62593,0.107256,NO,232,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.012,-3.566,2.554,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.0495842,0.00313441,0.107256 beta-lactamase_625_S233Q,beta-lactamase_625_233,TEM-1,beta-lactamase_625,P62593,0.107263,NO,233,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.886,-3.939,2.053,,0.016,E,B,0.27,-1.01,1.773,,77.62,BPO,-1.17267,0.213352,0.00311415,0.107263 beta-lactamase_2500_K71M,beta-lactamase_2500_71,TEM-1,beta-lactamase_2500,P62593,0.107279,NO,71,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-0.8,-4.48,3.68,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.361275,0.00103192,0.107279 beta-lactamase_L150P,beta-lactamase_150,TEM-1,beta-lactamase,P62593,0.107326,NO,150,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.326,-4.037,2.711,5.15566,,H,A,1.75,-0.2,1.615,,62.94,HHB,-1.86167,0.221079,0.00463171,0.107326 kka2_1:4_F133H,kka2_1:4_133,Kka2,kka2_1:4,P00552,0.107391,NO,133,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-0.871,-4.414,3.543,,0.178,.,B,0.58,0.43,0.786,,42.42,OHA,-0.871667,0.168804,0.00182168,0.107391 kka2_1:2_L60K,kka2_1:2_60,Kka2,kka2_1:2,P00552,0.107456,NO,60,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.997,-3.814,2.817,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.295029,0.00262176,0.107456 beta-lactamase_2500_P65D,beta-lactamase_2500_65,TEM-1,beta-lactamase_2500,P62593,0.107472,NO,65,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.894,-3.578,2.684,,0.098,E,B,0.52,-0.62,0.3,,40.56,HOH,-1.03233,0.361275,0.00152776,0.107472 kka2_1:2_D220K,kka2_1:2_220,Kka2,kka2_1:2,P00552,0.10749,NO,220,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.787,-3.529,2.742,,,H,A,0.75,-1.14,0.745,,46.59,PAH,-1.152,0.295029,0.00158066,0.10749 kka2_1:4_G213L,kka2_1:4_213,Kka2,kka2_1:4,P00552,0.107562,NO,213,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.596,-3.836,3.24,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.168804,0.00187654,0.107562 beta-lactamase_625_Y262D,beta-lactamase_625_262,TEM-1,beta-lactamase_625,P62593,0.107604,NO,262,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.213352,0.00853516,0.107604 PSD95pdz3_I327N,PSD95pdz3_327,PSD95pdz3,PSD95pdz3,P31016,0.107621,NO,327,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.63,-3.805,2.175,5.7413,,,,,14.0388,,,,PHH,-1.50167,0.0758425,0.000998774,0.107621 kka2_1:2_G189Q,kka2_1:2_189,Kka2,kka2_1:2,P00552,0.107662,NO,189,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.596,-4.153,3.557,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.295029,0.00253688,0.107662 beta-lactamase_39_S68P,beta-lactamase_39_68,TEM-1,beta-lactamase_39,P62593,0.107671,NO,68,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-0.913,-3.704,2.791,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.0495842,0.000800065,0.107671 beta-lactamase_2500_S128L,beta-lactamase_2500_128,TEM-1,beta-lactamase_2500,P62593,0.10773,NO,128,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-0.84,-3.358,2.518,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.361275,0.00071483,0.10773 beta-lactamase_2500_S128Y,beta-lactamase_2500_128,TEM-1,beta-lactamase_2500,P62593,0.107756,NO,128,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-0.84,-4.162,3.322,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.361275,0.00071483,0.107756 beta-lactamase_L74P,beta-lactamase_74,TEM-1,beta-lactamase,P62593,0.107801,NO,74,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.296,-4.001,2.705,5.50288,,H,A,1.75,-0.91,1.581,,50,HHO,-1.34933,0.221079,0.00493255,0.107801 beta-lactamase_2500_T178R,beta-lactamase_2500_178,TEM-1,beta-lactamase_2500,P62593,0.107838,NO,178,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-0.791,-3.708,2.917,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.361275,0.000684366,0.107838 kka2_1:2_V49E,kka2_1:2_49,Kka2,kka2_1:2,P00552,0.107882,NO,49,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.614,-3.892,2.278,,,E,B,0.44,-0.77,1.233,,64.39,HHB,-1.3,0.295029,0.00615685,0.107882 beta-lactamase_625_A133K,beta-lactamase_625_133,TEM-1,beta-lactamase_625,P62593,0.107904,NO,133,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.186,-3.614,2.428,,,H,A,0.46,-0.86,0.373,,67.83,HHP,-0.988333,0.213352,0.00468022,0.107904 beta-lactamase_156_L167W,beta-lactamase_156_167,TEM-1,beta-lactamase_156,P62593,0.10793,NO,167,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.138,-5.22,4.082,,0.015,G,A,0.55,-0.63,0.4,,64.69,AHP,-1.30767,0.111618,0.00303566,0.10793 beta-lactamase_156_V72D,beta-lactamase_156_72,TEM-1,beta-lactamase_156,P62593,0.107967,NO,72,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.658,-3.942,2.284,,,H,A,0.44,-1.03,1.92,,65.73,BHH,-1.32167,0.111618,0.00501194,0.107967 beta-lactamase_D155H,beta-lactamase_155,TEM-1,beta-lactamase,P62593,0.108027,NO,155,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.889,-4.424,3.535,4.92265,0.049,,B,0.45,-0.9,3.208,,64.69,OAB,-1.62267,0.221079,0.00135315,0.108027 beta-lactamase_N130I,beta-lactamase_130,TEM-1,beta-lactamase,P62593,0.108027,NO,130,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-0.798,-4.01,3.212,5.26686,0.069,H,A,1.08,-0.74,,,,APP,-0.980667,0.221079,0.000683376,0.108027 beta-lactamase_2500_G240P,beta-lactamase_2500_240,TEM-1,beta-lactamase_2500,P62593,0.108072,NO,240,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.361275,0.00591201,0.108072 beta-lactamase_156_A185H,beta-lactamase_156_185,TEM-1,beta-lactamase_156,P62593,0.108093,NO,185,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.406,-4.889,3.483,,,H,A,0.46,-1.02,0.365,,65.03,HHP,-1.84033,0.111618,0.00467449,0.108093 kka2_1:2_E199P,kka2_1:2_199,Kka2,kka2_1:2,P00552,0.108154,NO,199,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.234,-4.043,1.809,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.295029,0.00854122,0.108154 beta-lactamase_2500_S104L,beta-lactamase_2500_104,TEM-1,beta-lactamase_2500,P62593,0.108239,NO,104,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.015,-3.359,2.344,,0.04,,b,0.27,0.57,1.133,,63.29,HPO,-1.05267,0.361275,0.00218083,0.108239 beta-lactamase_2500_A124K,beta-lactamase_2500_124,TEM-1,beta-lactamase_2500,P62593,0.108311,NO,124,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.181,-3.561,2.38,,,H,A,0.46,-0.9,0.314,,64.34,HHH,-1.152,0.361275,0.00481399,0.108311 kka2_1:2_L223W,kka2_1:2_223,Kka2,kka2_1:2,P00552,0.108364,NO,223,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.861,-5.208,4.347,,,H,A,0.55,-1.24,0.266,,50,HHH,-0.854333,0.295029,0.00253574,0.108364 beta-lactamase_156_K232V,beta-lactamase_156_232,TEM-1,beta-lactamase_156,P62593,0.10838,NO,232,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.012,-3.626,2.614,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.111618,0.00313441,0.10838 beta-lactamase_D177M,beta-lactamase_177,TEM-1,beta-lactamase,P62593,0.108497,NO,177,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.967,-4.928,3.961,5.08038,0.006,T,L,1.59,-1.02,3.536,,64.69,BAP,-0.873667,0.221079,0.000864022,0.108497 beta-lactamase_625_T158E,beta-lactamase_625_158,TEM-1,beta-lactamase_625,P62593,0.108604,NO,158,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.116,-3.449,2.333,,0.036,,B,0.22,-0.85,3.771,,69.58,HPB,-1.269,0.213352,0.00341825,0.108604 kka2_1:4_R258F,kka2_1:4_258,Kka2,kka2_1:4,P00552,0.108721,NO,258,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.626,-4.327,2.701,,0.316,H,A,1.2,-0.85,2.655,,53.03,HBH,-1.25933,0.168804,0.00983174,0.108721 beta-lactamase_625_L150R,beta-lactamase_625_150,TEM-1,beta-lactamase_625,P62593,0.108735,NO,150,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.326,-3.982,2.656,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.213352,0.00463171,0.108735 kka2_1:4_Y218R,kka2_1:4_218,Kka2,kka2_1:4,P00552,0.108765,NO,218,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-1.438,-3.984,2.546,,0.122,H,A,0.21,-0.69,1.022,,56.06,BHP,-1.17533,0.168804,0.0126098,0.108765 kka2_1:4_R211T,kka2_1:4_211,Kka2,kka2_1:4,P00552,0.108786,NO,211,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-0.899,-3.493,2.594,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.168804,0.00204888,0.108786 beta-lactamase_2500_L284H,beta-lactamase_2500_284,TEM-1,beta-lactamase_2500,P62593,0.108801,NO,284,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.361275,0.0686156,0.108801 beta-lactamase_2500_G234H,beta-lactamase_2500_234,TEM-1,beta-lactamase_2500,P62593,0.108882,NO,234,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.62,-4.68,4.06,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.361275,0.000889577,0.108882 beta-lactamase_156_F228P,beta-lactamase_156_228,TEM-1,beta-lactamase_156,P62593,0.108962,NO,228,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-2.342,-3.088,0.746,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.111618,0.0046669,0.108962 kka2_1:2_C77M,kka2_1:2_77,Kka2,kka2_1:2,P00552,0.109035,NO,77,C,M,CM,Special,Hydrophobic,5.07,5.74,0.67,196,121,149,28,108.5,162.9,54.4,-1.477,-4.643,3.166,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.295029,0.00441216,0.109035 kka2_1:2_L67F,kka2_1:2_67,Kka2,kka2_1:2,P00552,0.109131,NO,67,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.741,-3.645,2.904,,0.007,H,A,1.59,-0.66,,,,BHP,-1.42867,0.295029,0.00102787,0.109131 beta-lactamase_625_M184P,beta-lactamase_625_184,TEM-1,beta-lactamase_625,P62593,0.10928,NO,184,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.593,-4.009,2.416,,,H,A,0.55,-0.87,2.765,,62.94,HHH,-1.41,0.213352,0.00356019,0.10928 kka2_1:4_D216I,kka2_1:4_216,Kka2,kka2_1:4,P00552,0.109285,NO,216,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.785,-4.062,3.277,,0.018,E,B,0.75,-0.51,0.112,,19.32,HAB,-0.970333,0.168804,0.00229969,0.109285 beta-lactamase_2500_A246P,beta-lactamase_2500_246,TEM-1,beta-lactamase_2500,P62593,0.109366,NO,246,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.121,-4.126,2.005,,0.01,E,B,0.46,-1.01,0.753,,73.78,HHH,-1.55633,0.361275,0.00569458,0.109366 kka2_1:8_F48E,kka2_1:8_48,Kka2,kka2_1:8,P00552,0.109393,NO,48,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.453,-3.968,2.515,,0.296,E,B,1.62,-0.99,14.194,14.194,55.3,HHH,-1.444,0.100394,0.00475422,0.109393 kka2_1:8_F48E,kka2_1:8_48,Kka2,kka2_1:8,P00552,0.109393,NO,48,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.453,-3.968,2.515,,0.296,E,B,1.62,-0.99,14.194,14.194,55.3,HHH,-1.444,0.100394,0.00475422,0.109393 beta-lactamase_2500_V259H,beta-lactamase_2500_259,TEM-1,beta-lactamase_2500,P62593,0.109457,NO,259,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.361275,0.0070773,0.109457 beta-lactamase_625_G243I,beta-lactamase_625_243,TEM-1,beta-lactamase_625,P62593,0.109471,NO,243,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.532,-3.58,2.048,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.213352,0.00464034,0.109471 beta-lactamase_2500_G236V,beta-lactamase_2500_236,TEM-1,beta-lactamase_2500,P62593,0.109528,NO,236,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.784,-3.686,2.902,,0.241,,b,0.29,-0.59,2.14,,64.69,HOO,-1.025,0.361275,0.00162372,0.109528 E1_Ubiquitin_G75E,E1_Ubiquitin_75,Uba1,E1_Ubiquitin,P0CG63,0.109637,NO,75,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.999,-3.405,2.406,,0.552,T,A,0.75,0.9,4.369,,83.73,BOO,-1.1,0.18783,0.00153276,0.109637 E1_Ubiquitin_G76N,E1_Ubiquitin_76,Uba1,E1_Ubiquitin,P0CG63,0.109637,NO,76,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.999,-3.475,2.476,,0.23,,B,0.75,0.08,1.702,,83.73,OOO,-0.999,0.18783,0.00125575,0.109637 Pab1_L133R,Pab1_133,Pab1,Pab1,P04147,0.109747,NO,133,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.039,-3.75,2.711,,0.015,,B,1.75,1.03,,,,PHB,-1.22,0.175299,0.000345939,0.109747 kka2_1:1_H188I,kka2_1:1_188,Kka2,kka2_1:1,P00552,0.109748,NO,188,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-0.913,-4.062,3.149,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.520039,0.00273139,0.109748 kka2_1:4_R226I,kka2_1:4_226,Kka2,kka2_1:4,P00552,0.109785,NO,226,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.392,-4.182,2.79,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.168804,0.0108032,0.109785 beta-lactamase_625_A124K,beta-lactamase_625_124,TEM-1,beta-lactamase_625,P62593,0.10987,NO,124,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.181,-3.561,2.38,,,H,A,0.46,-0.9,2.027,,64.34,HHH,-1.152,0.213352,0.00481399,0.10987 beta-lactamase_2500_I245W,beta-lactamase_2500_245,TEM-1,beta-lactamase_2500,P62593,0.110024,NO,245,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.361275,0.00391032,0.110024 beta-lactamase_2500_I125N,beta-lactamase_2500_125,TEM-1,beta-lactamase_2500,P62593,0.110043,NO,125,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.441,-4.089,2.648,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.361275,0.00383964,0.110043 beta-lactamase_2500_V31Q,beta-lactamase_2500_31,TEM-1,beta-lactamase_2500,P62593,0.11009,NO,31,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.822,-4.296,2.474,,,H,A,0.44,-0.46,0.955,,73.78,BHB,-2.03767,0.361275,0.00478065,0.11009 beta-lactamase_156_A185R,beta-lactamase_156_185,TEM-1,beta-lactamase_156,P62593,0.110117,NO,185,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.406,-3.963,2.557,,,H,A,0.46,-1.02,0.365,,65.03,HHP,-1.84033,0.111618,0.00467449,0.110117 beta-lactamase_2500_A185L,beta-lactamase_2500_185,TEM-1,beta-lactamase_2500,P62593,0.110166,NO,185,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.406,-2.064,0.658,,,H,A,0.46,-1.02,2.999,,65.03,HHP,-1.84033,0.361275,0.00467449,0.110166 beta-lactamase_625_Y44P,beta-lactamase_625_44,TEM-1,beta-lactamase_625,P62593,0.110198,NO,44,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-2.547,-4.12,1.573,,,E,B,0.21,-0.45,2.371,,73.78,OHH,-1.86267,0.213352,0.00426364,0.110198 kka2_1:1_A224Q,kka2_1:1_224,Kka2,kka2_1:1,P00552,0.110231,NO,224,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.977,-4.028,3.051,,,H,A,0.46,-1.26,1.725,,63.64,HHP,-1.41033,0.520039,0.00352047,0.110231 kka2_1:2_R217W,kka2_1:2_217,Kka2,kka2_1:2,P00552,0.110278,NO,217,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.158,-5.446,4.288,,0.252,T,A,1.2,-0.59,0.381,,52.27,ABH,-1.127,0.295029,0.0047191,0.110278 kka2_1:4_T187D,kka2_1:4_187,Kka2,kka2_1:4,P00552,0.110295,NO,187,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.273,-3.709,2.436,,0.007,E,B,0.22,-0.85,2.73,,52.27,HPB,-1.06567,0.168804,0.00693073,0.110295 beta-lactamase_156_S128K,beta-lactamase_156_128,TEM-1,beta-lactamase_156,P62593,0.1103,NO,128,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-0.84,-3.232,2.392,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.111618,0.00071483,0.1103 beta-lactamase_2500_L137K,beta-lactamase_2500_137,TEM-1,beta-lactamase_2500,P62593,0.110337,NO,137,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.03,-3.749,2.719,,,H,A,0.55,-0.38,0.769,,42.31,HHP,-1.58933,0.361275,0.00278599,0.110337 kka2_1:4_F256I,kka2_1:4_256,Kka2,kka2_1:4,P00552,0.110353,NO,256,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.49,-3.685,2.195,,,H,A,0.58,-0.78,1.653,,53.03,HHH,-1.423,0.168804,0.0132841,0.110353 beta-lactamase_625_T158W,beta-lactamase_625_158,TEM-1,beta-lactamase_625,P62593,0.110371,NO,158,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.116,-5.268,4.152,,0.036,,B,0.22,-0.85,3.771,,69.58,HPB,-1.269,0.213352,0.00341825,0.110371 beta-lactamase_2500_I125P,beta-lactamase_2500_125,TEM-1,beta-lactamase_2500,P62593,0.11038,NO,125,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.441,-4.116,2.675,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.361275,0.00383964,0.11038 kka2_1:1_E199F,kka2_1:1_199,Kka2,kka2_1:1,P00552,0.1104,NO,199,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.234,-4.372,2.138,,0.508,E,B,1.04,-0.43,3.012,,65.53,HAP,-2.133,0.520039,0.00854122,0.1104 kka2_1:2_T187R,kka2_1:2_187,Kka2,kka2_1:2,P00552,0.110551,NO,187,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.273,-3.94,2.667,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.295029,0.00693073,0.110551 kka2_1:4_R226N,kka2_1:4_226,Kka2,kka2_1:4,P00552,0.110551,NO,226,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.392,-3.682,2.29,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.168804,0.0108032,0.110551 beta-lactamase_156_Y44K,beta-lactamase_156_44,TEM-1,beta-lactamase_156,P62593,0.110558,NO,44,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-2.547,-3.823,1.276,,,E,B,0.21,-0.45,2.184,,73.78,OHH,-1.86267,0.111618,0.00426364,0.110558 beta-lactamase_L120E,beta-lactamase_120,TEM-1,beta-lactamase,P62593,0.110645,NO,120,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.044,-3.83,2.786,5.11974,,H,A,1.3,-1.13,1.988,,64.69,AHO,-1.13633,0.221079,0.00143563,0.110645 kka2_1:4_G88I,kka2_1:4_88,Kka2,kka2_1:4,P00552,0.110743,NO,88,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.689,-4.119,2.43,,0.54,S,l,0.29,1.51,7.899,,65.53,HOB,-1.718,0.168804,0.00685559,0.110743 beta-lactamase_2500_D174R,beta-lactamase_2500_174,TEM-1,beta-lactamase_2500,P62593,0.110874,NO,174,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.738,-3.933,3.195,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.361275,0.00125633,0.110874 beta-lactamase_W208K,beta-lactamase_208,TEM-1,beta-lactamase,P62593,0.110877,NO,208,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-0.818,-3.907,3.089,5.26277,0.067,H,A,0.99,-0.65,,,,AHH,-1.44133,0.221079,0.00126609,0.110877 beta-lactamase_2500_L248H,beta-lactamase_2500_248,TEM-1,beta-lactamase_2500,P62593,0.110922,NO,248,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.361275,0.00428493,0.110922 kka2_1:2_E96Y,kka2_1:2_96,Kka2,kka2_1:2,P00552,0.110959,NO,96,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.573,-4.313,1.74,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.295029,0.00369441,0.110959 kka2_1:4_F256N,kka2_1:4_256,Kka2,kka2_1:4,P00552,0.110961,NO,256,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.49,-4.16,2.67,,,H,A,0.58,-0.78,1.653,,53.03,HHH,-1.423,0.168804,0.0132841,0.110961 beta-lactamase_2500_I258R,beta-lactamase_2500_258,TEM-1,beta-lactamase_2500,P62593,0.110972,NO,258,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.361275,0.007931,0.110972 beta-lactamase_2500_L136G,beta-lactamase_2500_136,TEM-1,beta-lactamase_2500,P62593,0.110989,NO,136,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.232,-3.856,2.624,,,H,A,0.55,-0.34,1.36,,48.95,HHH,-1.088,0.361275,0.00442304,0.110989 beta-lactamase_V31P,beta-lactamase_31,TEM-1,beta-lactamase,P62593,0.111081,NO,31,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.822,-4.128,2.306,5.43781,,H,A,2.78,-0.46,2.885,,73.78,BHB,-2.03767,0.221079,0.00478065,0.111081 beta-lactamase_2500_G142L,beta-lactamase_2500_142,TEM-1,beta-lactamase_2500,P62593,0.111082,NO,142,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.707,-3.771,3.064,,0.034,,p,0.29,-0.64,1.883,,64.69,OOO,-0.834,0.361275,0.00060149,0.111082 beta-lactamase_V82P,beta-lactamase_82,TEM-1,beta-lactamase,P62593,0.111115,NO,82,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.325,-4.008,2.683,5.27777,0.267,H,A,0.96,0.08,1.379,,93.01,BHA,-1.28567,0.221079,0.00397046,0.111115 kka2_1:2_F206M,kka2_1:2_206,Kka2,kka2_1:2,P00552,0.111137,NO,206,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.349,-3.155,1.806,,0.006,E,B,0.58,-1.21,0.978,,63.64,OHH,-1.04,0.295029,0.00936868,0.111137 beta-lactamase_2500_N168I,beta-lactamase_2500_168,TEM-1,beta-lactamase_2500,P62593,0.111171,NO,168,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-1.029,-3.943,2.914,,0.113,G,A,0.61,-0.4,2.9,,44.41,HPA,-1.13233,0.361275,0.00288667,0.111171 kka2_1:2_I115F,kka2_1:2_115,Kka2,kka2_1:2,P00552,0.11127,NO,115,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.606,-3.062,1.456,,0.105,H,A,0.48,-1.18,0.878,,65.53,PHH,-2.205,0.295029,0.00836567,0.11127 beta-lactamase_2500_Q203P,beta-lactamase_2500_203,TEM-1,beta-lactamase_2500,P62593,0.111306,NO,203,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.168,-3.941,1.773,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.361275,0.00631514,0.111306 beta-lactamase_2500_M209D,beta-lactamase_2500_209,TEM-1,beta-lactamase_2500,P62593,0.111324,NO,209,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.442,-4.067,2.625,,,H,A,0.55,-0.97,3.229,,64.69,HHA,-1.52633,0.361275,0.00625021,0.111324 beta-lactamase_I256N,beta-lactamase_256,TEM-1,beta-lactamase,P62593,0.11142,NO,256,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.621,-4.224,2.603,5.3196,,E,B,1,-0.84,1.615,,73.08,BHH,-1.80667,0.221079,0.00710634,0.11142 beta-lactamase_K71R,beta-lactamase_71,TEM-1,beta-lactamase,P62593,0.11142,NO,71,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-0.8,-3.033,2.233,5.15697,,H,A,1.3,-0.99,,,,HBH,-1.209,0.221079,0.00103192,0.11142 beta-lactamase_625_A132D,beta-lactamase_625_132,TEM-1,beta-lactamase_625,P62593,0.111534,NO,132,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.9,-3.706,2.806,,,H,A,0.46,-0.93,0.316,,64.69,PHH,-1.138,0.213352,0.000962524,0.111534 gb1_A260D,gb1_260,gb1,gb1,P06654,0.111535,NO,260,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.486,-3.711,2.225,,,,,,,0.173,,9.6,HHP,-1.70967,0.177985,0.0055808,0.111535 gb1_A260E,gb1_260,gb1,gb1,P06654,0.111535,NO,260,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.486,-3.457,1.971,,,,,,,0.173,,9.6,HHP,-1.70967,0.177985,0.0055808,0.111535 gb1_A260K,gb1_260,gb1,gb1,P06654,0.111535,NO,260,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.486,-3.429,1.943,,,,,,,0.173,,9.6,HHP,-1.70967,0.177985,0.0055808,0.111535 gb1_A260P,gb1_260,gb1,gb1,P06654,0.111535,NO,260,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.486,-3.672,2.186,,,,,,,0.173,,9.6,HHP,-1.70967,0.177985,0.0055808,0.111535 gb1_E253P,gb1_253,gb1,gb1,P06654,0.111535,NO,253,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.71,-3.666,1.956,,,,,,,0.529,,11.83,HAB,-1.54433,0.177985,0.00141452,0.111535 gb1_F256D,gb1_256,gb1,gb1,P06654,0.111535,NO,256,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.241,-3.696,2.455,,,,,,,,,,HHB,-2.04767,0.177985,0.00435993,0.111535 gb1_F278D,gb1_278,gb1,gb1,P06654,0.111535,NO,278,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.418,-3.292,1.874,,,,,,,3.233,,35.71,PHP,-1.503,0.177985,0.00295699,0.111535 gb1_F278E,gb1_278,gb1,gb1,P06654,0.111535,NO,278,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.418,-2.13,0.712,,,,,,,3.233,,35.71,PHP,-1.503,0.177985,0.00295699,0.111535 gb1_F278K,gb1_278,gb1,gb1,P06654,0.111535,NO,278,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.418,-3.398,1.98,,,,,,,3.233,,35.71,PHP,-1.503,0.177985,0.00295699,0.111535 gb1_F278N,gb1_278,gb1,gb1,P06654,0.111535,NO,278,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.418,-3.72,2.302,,,,,,,3.233,,35.71,PHP,-1.503,0.177985,0.00295699,0.111535 gb1_F278P,gb1_278,gb1,gb1,P06654,0.111535,NO,278,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.418,-3.926,2.508,,,,,,,3.233,,35.71,PHP,-1.503,0.177985,0.00295699,0.111535 gb1_F278Q,gb1_278,gb1,gb1,P06654,0.111535,NO,278,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.418,-3.723,2.305,,,,,,,3.233,,35.71,PHP,-1.503,0.177985,0.00295699,0.111535 gb1_F278R,gb1_278,gb1,gb1,P06654,0.111535,NO,278,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.418,-3.755,2.337,,,,,,,3.233,,35.71,PHP,-1.503,0.177985,0.00295699,0.111535 gb1_G267H,gb1_267,gb1,gb1,P06654,0.111535,NO,267,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.676,-4.557,2.881,,,,,,,1.361,,12.72,AOA,-1.61833,0.177985,0.00264655,0.111535 gb1_G267K,gb1_267,gb1,gb1,P06654,0.111535,NO,267,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.676,-3.559,1.883,,,,,,,1.361,,12.72,AOA,-1.61833,0.177985,0.00264655,0.111535 gb1_G267P,gb1_267,gb1,gb1,P06654,0.111535,NO,267,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.676,-3.84,2.164,,,,,,,1.361,,12.72,AOA,-1.61833,0.177985,0.00264655,0.111535 gb1_G267Q,gb1_267,gb1,gb1,P06654,0.111535,NO,267,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.676,-4.001,2.325,,,,,,,1.361,,12.72,AOA,-1.61833,0.177985,0.00264655,0.111535 gb1_G267R,gb1_267,gb1,gb1,P06654,0.111535,NO,267,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.676,-3.81,2.134,,,,,,,1.361,,12.72,AOA,-1.61833,0.177985,0.00264655,0.111535 gb1_G267T,gb1_267,gb1,gb1,P06654,0.111535,NO,267,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.676,-3.367,1.691,,,,,,,1.361,,12.72,AOA,-1.61833,0.177985,0.00264655,0.111535 gb1_I232P,gb1_232,gb1,gb1,P06654,0.111535,NO,232,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-2.175,-3.757,1.582,,,,,,,0.766,,44.87,HHH,-2.152,0.177985,0.00580459,0.111535 gb1_K257I,gb1_257,gb1,gb1,P06654,0.111535,NO,257,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.775,-3.899,2.124,,,,,,,0.896,,37.28,HBP,-1.70367,0.177985,0.00640304,0.111535 gb1_K257N,gb1_257,gb1,gb1,P06654,0.111535,NO,257,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.775,-3.336,1.561,,,,,,,0.896,,37.28,HBP,-1.70367,0.177985,0.00640304,0.111535 gb1_K257P,gb1_257,gb1,gb1,P06654,0.111535,NO,257,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.775,-3.613,1.838,,,,,,,0.896,,37.28,HBP,-1.70367,0.177985,0.00640304,0.111535 gb1_K257Q,gb1_257,gb1,gb1,P06654,0.111535,NO,257,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.775,-1.999,0.224,,,,,,,0.896,,37.28,HBP,-1.70367,0.177985,0.00640304,0.111535 gb1_L231D,gb1_231,gb1,gb1,P06654,0.111535,NO,231,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.603,-3.836,2.233,,,,,,,0.219,,11.83,BHH,-1.82633,0.177985,0.00322797,0.111535 gb1_W269A,gb1_269,gb1,gb1,P06654,0.111535,NO,269,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-1.198,-3.305,2.107,,,,,,,,,,AHP,-2.08867,0.177985,0.00270706,0.111535 gb1_W269H,gb1_269,gb1,gb1,P06654,0.111535,NO,269,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-1.198,-4.457,3.259,,,,,,,,,,AHP,-2.08867,0.177985,0.00270706,0.111535 gb1_W269L,gb1_269,gb1,gb1,P06654,0.111535,NO,269,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-1.198,-3.135,1.937,,,,,,,,,,AHP,-2.08867,0.177985,0.00270706,0.111535 gb1_W269T,gb1_269,gb1,gb1,P06654,0.111535,NO,269,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-1.198,-3.423,2.225,,,,,,,,,,AHP,-2.08867,0.177985,0.00270706,0.111535 beta-lactamase_2500_M66R,beta-lactamase_2500_66,TEM-1,beta-lactamase_2500,P62593,0.111552,NO,66,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.362,-3.923,2.561,,0.013,,A,0.55,-0.7,0.502,,73.08,OHH,-1.49567,0.361275,0.00412876,0.111552 kka2_1:2_R258M,kka2_1:2_258,Kka2,kka2_1:2,P00552,0.111582,NO,258,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.626,-3.325,1.699,,0.316,H,A,1.2,-0.85,7.485,7.485,53.03,HBH,-1.25933,0.295029,0.00983174,0.111582 kka2_1:8_R253W,kka2_1:8_253,Kka2,kka2_1:8,P00552,0.111614,NO,253,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.356,-5.444,4.088,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.100394,0.0144195,0.111614 kka2_1:8_R253W,kka2_1:8_253,Kka2,kka2_1:8,P00552,0.111614,NO,253,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.356,-5.444,4.088,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.100394,0.0144195,0.111614 kka2_1:4_V185P,kka2_1:4_185,Kka2,kka2_1:4,P00552,0.111645,NO,185,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.045,-4.002,2.957,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.168804,0.00367031,0.111645 beta-lactamase_625_K71F,beta-lactamase_625_71,TEM-1,beta-lactamase_625,P62593,0.11168,NO,71,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-0.8,-4.292,3.492,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.213352,0.00103192,0.11168 kka2_1:2_R140W,kka2_1:2_140,Kka2,kka2_1:2,P00552,0.111687,NO,140,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.351,-5.43,4.079,,0.12,H,A,1.2,0.2,0.352,,53.03,BBH,-1.885,0.295029,0.00430167,0.111687 beta-lactamase_2500_A133Y,beta-lactamase_2500_133,TEM-1,beta-lactamase_2500,P62593,0.111786,NO,133,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.186,-4.319,3.133,,,H,A,0.46,-0.86,2.649,,67.83,HHP,-0.988333,0.361275,0.00468022,0.111786 kka2_1:1_V46F,kka2_1:1_46,Kka2,kka2_1:1,P00552,0.111818,NO,46,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-2.62,-3.464,0.844,,0.192,.,B,0.44,-1.12,20.149,20.149,92.05,OHH,-1.88633,0.520039,0.00631301,0.111818 beta-lactamase_2500_L167D,beta-lactamase_2500_167,TEM-1,beta-lactamase_2500,P62593,0.111895,NO,167,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.138,-4.03,2.892,,0.015,G,A,0.55,-0.63,7.813,,64.69,AHP,-1.30767,0.361275,0.00303566,0.111895 kka2_1:2_D216I,kka2_1:2_216,Kka2,kka2_1:2,P00552,0.111899,NO,216,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.785,-4.062,3.277,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.295029,0.00229969,0.111899 kka2_1:2_V186K,kka2_1:2_186,Kka2,kka2_1:2,P00552,0.111915,NO,186,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.011,-3.841,2.83,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.295029,0.00409703,0.111915 beta-lactamase_625_V42K,beta-lactamase_625_42,TEM-1,beta-lactamase_625,P62593,0.112014,NO,42,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.564,-3.817,2.253,,0.017,E,B,0.44,-0.51,2.576,,63.99,BHO,-1.042,0.213352,0.00404515,0.112014 kka2_1:4_T187M,kka2_1:4_187,Kka2,kka2_1:4,P00552,0.112164,NO,187,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.273,-4.606,3.333,,0.007,E,B,0.22,-0.85,2.73,,52.27,HPB,-1.06567,0.168804,0.00693073,0.112164 beta-lactamase_2500_D177Q,beta-lactamase_2500_177,TEM-1,beta-lactamase_2500,P62593,0.11227,NO,177,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.967,-3.799,2.832,,0.006,T,L,0.75,-1.02,4.131,,64.69,BAP,-0.873667,0.361275,0.000864022,0.11227 beta-lactamase_L282R,beta-lactamase_282,TEM-1,beta-lactamase,P62593,0.112369,NO,282,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.586,-4.105,2.519,5.16743,0.007,H,A,1.07,0.34,31.31,31.31,63.99,PHH,-1.82367,0.221079,0.0449821,0.112369 kka2_1:1_D82Q,kka2_1:1_82,Kka2,kka2_1:1,P00552,0.112392,NO,82,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.946,-2.981,1.035,,0.341,E,b,0.75,0.52,11.345,11.345,63.64,HAH,-1.98,0.520039,0.00637516,0.112392 beta-lactamase_625_A133Y,beta-lactamase_625_133,TEM-1,beta-lactamase_625,P62593,0.112485,NO,133,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.186,-4.319,3.133,,,H,A,0.46,-0.86,0.373,,67.83,HHP,-0.988333,0.213352,0.00468022,0.112485 beta-lactamase_2500_N134Y,beta-lactamase_2500_134,TEM-1,beta-lactamase_2500,P62593,0.112577,NO,134,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-0.879,-4.188,3.309,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.361275,0.000644786,0.112577 beta-lactamase_G239V,beta-lactamase_239,TEM-1,beta-lactamase,P62593,0.112589,NO,239,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.819,-3.683,2.864,4.85529,0.115,T,l,0.77,-0.62,1.817,,42.31,BOP,-1.45267,0.221079,0.00213852,0.112589 kka2_1:8_G30I,kka2_1:8_30,Kka2,kka2_1:8,P00552,0.112596,NO,30,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.596,-4.264,3.668,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.100394,0.00159208,0.112596 kka2_1:8_G30I,kka2_1:8_30,Kka2,kka2_1:8,P00552,0.112596,NO,30,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.596,-4.264,3.668,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.100394,0.00159208,0.112596 beta-lactamase_39_E164P,beta-lactamase_39_164,TEM-1,beta-lactamase_39,P62593,0.112612,NO,164,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-0.948,-3.725,2.777,,0.011,T,B,1.04,-0.4,0.664,,64.69,HAO,-1.388,0.0495842,0.00137286,0.112612 beta-lactamase_2500_R59E,beta-lactamase_2500_59,TEM-1,beta-lactamase_2500,P62593,0.112644,NO,59,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.345,-3.322,1.977,,0.329,S,L,1.2,-0.09,3.719,,73.08,HBO,-2.24267,0.361275,0.00318082,0.112644 beta-lactamase_625_L74F,beta-lactamase_625_74,TEM-1,beta-lactamase_625,P62593,0.112689,NO,74,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.296,-3.848,2.552,,,H,A,0.55,-0.91,0.895,,50,HHO,-1.34933,0.213352,0.00493255,0.112689 beta-lactamase_625_M209P,beta-lactamase_625_209,TEM-1,beta-lactamase_625,P62593,0.112708,NO,209,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.442,-4.077,2.635,,,H,A,0.55,-0.97,1.167,,64.69,HHA,-1.52633,0.213352,0.00625021,0.112708 kka2_1:4_G205Y,kka2_1:4_205,Kka2,kka2_1:4,P00552,0.112757,NO,205,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.596,-4.416,3.82,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.168804,0.00221855,0.112757 beta-lactamase_625_I280N,beta-lactamase_625_280,TEM-1,beta-lactamase_625,P62593,0.112789,NO,280,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.213352,0.0530888,0.112789 beta-lactamase_G234E,beta-lactamase_234,TEM-1,beta-lactamase,P62593,0.112822,NO,234,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.62,-3.665,3.045,4.24221,0.023,E,B,0.46,-0.86,,,,POH,-1.25733,0.221079,0.000889577,0.112822 Ubiquitin_N25P,Ubiquitin_25,Uba1,Ubiquitin,P0CG48,0.112903,NO,25,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-1.95,-3.945,1.995,4.76563,0.444,H,A,0.09,0,2.3,,31.09,APH,-1.741,0.205827,0.00071919,0.112903 beta-lactamase_156_D161P,beta-lactamase_156_161,TEM-1,beta-lactamase_156,P62593,0.112917,NO,161,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.891,-3.704,2.813,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.111618,0.000897697,0.112917 kka2_1:4_A78D,kka2_1:4_78,Kka2,kka2_1:4,P00552,0.113041,NO,78,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.744,-3.601,1.857,,0.078,.,B,0.46,-0.53,0.594,,56.06,OHH,-1.863,0.168804,0.00457299,0.113041 beta-lactamase_2500_D83W,beta-lactamase_2500_83,TEM-1,beta-lactamase_2500,P62593,0.113055,NO,83,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.066,-5.509,4.443,,0.354,H,A,0.75,0.22,0.239,,48.95,HAH,-1.34733,0.361275,0.00205968,0.113055 beta-lactamase_39_I244P,beta-lactamase_39_244,TEM-1,beta-lactamase_39,P62593,0.113083,NO,244,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.555,-4.01,2.455,,,E,B,0.48,-0.84,1.325,,77.62,OHH,-1.385,0.0495842,0.00605379,0.113083 beta-lactamase_625_M66K,beta-lactamase_625_66,TEM-1,beta-lactamase_625,P62593,0.113171,NO,66,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.362,-3.657,2.295,,0.013,,A,0.55,-0.7,1.659,,73.08,OHH,-1.49567,0.213352,0.00412876,0.113171 E1_Ubiquitin_G76F,E1_Ubiquitin_76,Uba1,E1_Ubiquitin,P0CG63,0.113174,NO,76,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.999,-3.858,2.859,,0.23,,B,0.75,0.08,1.702,,83.73,OOO,-0.999,0.18783,0.00125575,0.113174 kka2_1:2_P12F,kka2_1:2_12,Kka2,kka2_1:2,P00552,0.113188,NO,12,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.853,-4.467,3.614,,,.,B,0.52,1.25,0.261,,48.11,POH,-1.80767,0.295029,0.00500011,0.113188 kka2_1:2_F263C,kka2_1:2_263,Kka2,kka2_1:2,P00552,0.11322,NO,263,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-0.911,-4.889,3.978,,0.006,G,A,1.62,-0.12,5.275,,45.83,AHH,-0.92,0.295029,0.0172454,0.11322 beta-lactamase_39_S68N,beta-lactamase_39_68,TEM-1,beta-lactamase_39,P62593,0.113239,NO,68,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-0.913,-2.44,1.527,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.0495842,0.000800065,0.113239 kka2_1:2_M116P,kka2_1:2_116,Kka2,kka2_1:2,P00552,0.113308,NO,116,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-2.482,-4.193,1.711,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.295029,0.00745147,0.113308 beta-lactamase_625_A185P,beta-lactamase_625_185,TEM-1,beta-lactamase_625,P62593,0.113374,NO,185,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.406,-2.861,1.455,,,H,A,0.46,-1.02,0.365,,65.03,HHP,-1.84033,0.213352,0.00467449,0.113374 kka2_1:2_R226N,kka2_1:2_226,Kka2,kka2_1:2,P00552,0.113448,NO,226,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.392,-3.682,2.29,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.295029,0.0108032,0.113448 beta-lactamase_D155V,beta-lactamase_155,TEM-1,beta-lactamase,P62593,0.113509,NO,155,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.889,-3.778,2.889,4.92265,0.049,,B,0.45,-0.9,3.208,,64.69,OAB,-1.62267,0.221079,0.00135315,0.113509 kka2_1:2_F37D,kka2_1:2_37,Kka2,kka2_1:2,P00552,0.113608,NO,37,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.427,-4.022,2.595,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.295029,0.00586193,0.113608 beta-lactamase_2500_L73D,beta-lactamase_2500_73,TEM-1,beta-lactamase_2500,P62593,0.113677,NO,73,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.507,-4.091,2.584,,,H,A,0.55,-0.64,2.178,,67.83,HHH,-1.487,0.361275,0.00488983,0.113677 kka2_1:2_F48E,kka2_1:2_48,Kka2,kka2_1:2,P00552,0.113702,NO,48,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.453,-3.968,2.515,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.295029,0.00475422,0.113702 kka2_1:1_P128H,kka2_1:1_128,Kka2,kka2_1:1,P00552,0.113703,NO,128,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.922,-4.964,3.042,,0.316,G,A,0.52,0.4,2.178,,56.06,AOH,-1.64733,0.520039,0.00774689,0.113703 kka2_1:1_V198F,kka2_1:1_198,Kka2,kka2_1:1,P00552,0.113733,NO,198,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.719,-4.163,2.444,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.520039,0.00835002,0.113733 beta-lactamase_156_F64P,beta-lactamase_156_64,TEM-1,beta-lactamase_156,P62593,0.113819,NO,64,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-0.841,-4.33,3.489,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.111618,0.000947691,0.113819 Pab1_G169L,Pab1_169,Pab1,Pab1,P04147,0.113828,NO,169,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.809,-3.625,2.816,,,E,b,0.35,0.03,,,,HOH,-1.11567,0.175299,0.000302434,0.113828 beta-lactamase_T158D,beta-lactamase_158,TEM-1,beta-lactamase,P62593,0.113872,NO,158,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.116,-3.478,2.362,5.32011,0.036,,B,0.98,-0.85,2.755,,69.58,HPB,-1.269,0.221079,0.00341825,0.113872 beta-lactamase_2500_G236L,beta-lactamase_2500_236,TEM-1,beta-lactamase_2500,P62593,0.113948,NO,236,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.784,-3.712,2.928,,0.241,,b,0.29,-0.59,2.14,,64.69,HOO,-1.025,0.361275,0.00162372,0.113948 kka2_1:2_L123W,kka2_1:2_123,Kka2,kka2_1:2,P00552,0.113968,NO,123,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.888,-5.165,4.277,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.295029,0.00325188,0.113968 kka2_1:4_C209N,kka2_1:4_209,Kka2,kka2_1:4,P00552,0.114122,NO,209,C,N,CN,Special,Polar,5.07,5.47157,0.401575,139,121,132,11,108.5,114.1,5.6,-0.906,-4.174,3.268,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.168804,0.00260862,0.114122 kka2_1:4_G164I,kka2_1:4_164,Kka2,kka2_1:4,P00552,0.114194,NO,164,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.869,-4.238,3.369,,0.862,T,l,0.75,1.45,1.539,,64.39,POH,-1.828,0.168804,0.00442091,0.114194 beta-lactamase_2500_T107H,beta-lactamase_2500_107,TEM-1,beta-lactamase_2500,P62593,0.114278,NO,107,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.117,-4.67,3.553,,,G,A,0.22,-0.06,2.686,,67.83,HPA,-1.265,0.361275,0.00239347,0.114278 beta-lactamase_625_L150K,beta-lactamase_625_150,TEM-1,beta-lactamase_625,P62593,0.114292,NO,150,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.326,-3.711,2.385,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.213352,0.00463171,0.114292 kka2_1:8_N195E,kka2_1:8_195,Kka2,kka2_1:8,P00552,0.114308,NO,195,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-0.836,-3.211,2.375,,0.037,G,A,0.43,-1.36,1.108,,48.11,OPH,-1.26567,0.100394,0.00276134,0.114308 kka2_1:8_N195E,kka2_1:8_195,Kka2,kka2_1:8,P00552,0.114308,NO,195,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-0.836,-3.211,2.375,,0.037,G,A,0.43,-1.36,1.108,,48.11,OPH,-1.26567,0.100394,0.00276134,0.114308 kka2_1:2_D216Q,kka2_1:2_216,Kka2,kka2_1:2,P00552,0.114329,NO,216,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.785,-3.726,2.941,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.295029,0.00229969,0.114329 kka2_1:1_L232T,kka2_1:1_232,Kka2,kka2_1:1,P00552,0.114342,NO,232,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.514,-3.677,2.163,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.520039,0.00800103,0.114342 kka2_1:1_L232K,kka2_1:1_232,Kka2,kka2_1:1,P00552,0.114398,NO,232,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.514,-3.945,2.431,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.520039,0.00800103,0.114398 beta-lactamase_156_G234W,beta-lactamase_156_234,TEM-1,beta-lactamase_156,P62593,0.114534,NO,234,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.62,-5.097,4.477,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.111618,0.000889577,0.114534 kka2_1:8_G233N,kka2_1:8_233,Kka2,kka2_1:8,P00552,0.114552,NO,233,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.748,-3.476,2.728,,0.172,,b,0.75,-0.27,1.134,,49.24,HOO,-1.72067,0.100394,0.00232366,0.114552 kka2_1:8_G233N,kka2_1:8_233,Kka2,kka2_1:8,P00552,0.114552,NO,233,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.748,-3.476,2.728,,0.172,,b,0.75,-0.27,1.134,,49.24,HOO,-1.72067,0.100394,0.00232366,0.114552 kka2_1:8_L174Y,kka2_1:8_174,Kka2,kka2_1:8,P00552,0.114552,NO,174,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.952,-4.056,3.104,,,H,A,1.59,-0.31,1.204,,51.89,BHB,-2.08533,0.100394,0.00438501,0.114552 kka2_1:8_L174Y,kka2_1:8_174,Kka2,kka2_1:8,P00552,0.114552,NO,174,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.952,-4.056,3.104,,,H,A,1.59,-0.31,1.204,,51.89,BHB,-2.08533,0.100394,0.00438501,0.114552 kka2_1:4_R226W,kka2_1:4_226,Kka2,kka2_1:4,P00552,0.114564,NO,226,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.392,-2.291,0.899,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.168804,0.0108032,0.114564 beta-lactamase_156_A133H,beta-lactamase_156_133,TEM-1,beta-lactamase_156,P62593,0.114652,NO,133,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.186,-4.769,3.583,,,H,A,0.46,-0.86,0.805,,67.83,HHP,-0.988333,0.111618,0.00468022,0.114652 kka2_1:1_G213W,kka2_1:1_213,Kka2,kka2_1:1,P00552,0.114663,NO,213,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.596,-5.126,4.53,,,E,b,0.29,-0.4,,,,HOH,-0.920333,0.520039,0.00187654,0.114663 kka2_1:2_R44D,kka2_1:2_44,Kka2,kka2_1:2,P00552,0.114671,NO,44,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.062,-3.066,1.004,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.295029,0.00745043,0.114671 beta-lactamase_156_M184P,beta-lactamase_156_184,TEM-1,beta-lactamase_156,P62593,0.114694,NO,184,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.593,-4.009,2.416,,,H,A,0.55,-0.87,1.671,,62.94,HHH,-1.41,0.111618,0.00356019,0.114694 kka2_1:2_M116Q,kka2_1:2_116,Kka2,kka2_1:2,P00552,0.114715,NO,116,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-2.482,-4.256,1.774,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.295029,0.00745147,0.114715 kka2_1:1_A78F,kka2_1:1_78,Kka2,kka2_1:1,P00552,0.114726,NO,78,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.744,-4.44,2.696,,0.078,.,B,0.46,-0.53,0.206,,56.06,OHH,-1.863,0.520039,0.00457299,0.114726 PSD95pdz3_A347F,PSD95pdz3_347,PSD95pdz3,PSD95pdz3,P31016,0.114787,NO,347,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.307,-3.749,2.442,4.89689,,,,,15.176,,,,OHA,-1.269,0.0758425,0.00074525,0.114787 beta-lactamase_2500_S68R,beta-lactamase_2500_68,TEM-1,beta-lactamase_2500,P62593,0.114788,NO,68,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-0.913,-3.705,2.792,,0.064,G,A,0.27,-1.03,2.824,,64.69,HPP,-1.37233,0.361275,0.000800065,0.114788 kka2_1:2_L94W,kka2_1:2_94,Kka2,kka2_1:2,P00552,0.11488,NO,94,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.618,-5.174,3.556,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.295029,0.00520888,0.11488 kka2_1:2_Y22P,kka2_1:2_22,Kka2,kka2_1:2,P00552,0.114948,NO,22,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-1.583,-4.113,2.53,,0.122,.,B,0.21,-0.8,1.838,,65.53,OHA,-1.80333,0.295029,0.00598977,0.114948 beta-lactamase_156_V260K,beta-lactamase_156_260,TEM-1,beta-lactamase_156,P62593,0.114969,NO,260,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.111618,0.00471757,0.114969 beta-lactamase_156_V260P,beta-lactamase_156_260,TEM-1,beta-lactamase_156,P62593,0.11513,NO,260,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.111618,0.00471757,0.11513 beta-lactamase_39_P181D,beta-lactamase_39_181,TEM-1,beta-lactamase_39,P62593,0.115137,NO,181,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.813,-3.518,2.705,,,H,A,0.52,-1.14,1.946,,61.54,HOH,-1.795,0.0495842,0.000703122,0.115137 beta-lactamase_156_T178P,beta-lactamase_156_178,TEM-1,beta-lactamase_156,P62593,0.115139,NO,178,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-0.791,-3.655,2.864,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.111618,0.000684366,0.115139 beta-lactamase_625_R162Y,beta-lactamase_625_162,TEM-1,beta-lactamase_625,P62593,0.115313,NO,162,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.016,-4.207,3.191,,0.124,S,B,1.2,-0.37,1.445,,64.69,ABH,-1.25,0.213352,0.000561334,0.115313 kka2_1:2_T225R,kka2_1:2_225,Kka2,kka2_1:2,P00552,0.115535,NO,225,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.393,-4.06,1.667,,0.036,H,A,0.22,-1.22,4.554,,63.64,HPB,-1.58733,0.295029,0.0113598,0.115535 beta-lactamase_625_W227P,beta-lactamase_625_227,TEM-1,beta-lactamase_625,P62593,0.115564,NO,227,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-0.982,-4.323,3.341,,0.272,,B,0.47,-0.29,2.533,,74.48,OHH,-1.595,0.213352,0.00226019,0.115564 beta-lactamase_2500_P143D,beta-lactamase_2500_143,TEM-1,beta-lactamase_2500,P62593,0.115641,NO,143,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.967,-3.622,2.655,,0.075,H,A,0.52,-0.37,0.479,,66.78,OOB,-1.354,0.361275,0.00114551,0.115641 beta-lactamase_625_G43I,beta-lactamase_625_43,TEM-1,beta-lactamase_625,P62593,0.115661,NO,43,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.62,-4.235,3.615,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.213352,0.00120151,0.115661 beta-lactamase_2500_E35I,beta-lactamase_2500_35,TEM-1,beta-lactamase_2500,P62593,0.115823,NO,35,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-0.869,-4.036,3.167,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.361275,0.00174441,0.115823 beta-lactamase_2500_M184W,beta-lactamase_2500_184,TEM-1,beta-lactamase_2500,P62593,0.11589,NO,184,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.593,-5.149,3.556,,,H,A,0.55,-0.87,2.893,,62.94,HHH,-1.41,0.361275,0.00356019,0.11589 beta-lactamase_39_G234D,beta-lactamase_39_234,TEM-1,beta-lactamase_39,P62593,0.115893,NO,234,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.62,-3.469,2.849,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.0495842,0.000889577,0.115893 beta-lactamase_156_Y44R,beta-lactamase_156_44,TEM-1,beta-lactamase_156,P62593,0.115916,NO,44,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-2.547,-4.123,1.576,,,E,B,0.21,-0.45,2.184,,73.78,OHH,-1.86267,0.111618,0.00426364,0.115916 kka2_1:4_V75K,kka2_1:4_75,Kka2,kka2_1:4,P00552,0.115962,NO,75,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-2.06,-3.819,1.759,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.168804,0.00693733,0.115962 beta-lactamase_625_S68D,beta-lactamase_625_68,TEM-1,beta-lactamase_625,P62593,0.116011,NO,68,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-0.913,-3.241,2.328,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.213352,0.000800065,0.116011 beta-lactamase_39_G234W,beta-lactamase_39_234,TEM-1,beta-lactamase_39,P62593,0.116018,NO,234,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.62,-5.097,4.477,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.0495842,0.000889577,0.116018 beta-lactamase_156_L136H,beta-lactamase_156_136,TEM-1,beta-lactamase_156,P62593,0.116053,NO,136,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.232,-4.999,3.767,,,H,A,0.55,-0.34,1.04,,48.95,HHH,-1.088,0.111618,0.00442304,0.116053 beta-lactamase_2500_T178K,beta-lactamase_2500_178,TEM-1,beta-lactamase_2500,P62593,0.116117,NO,178,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-0.791,-3.457,2.666,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.361275,0.000684366,0.116117 kka2_1:4_G213N,kka2_1:4_213,Kka2,kka2_1:4,P00552,0.116236,NO,213,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.596,-3.476,2.88,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.168804,0.00187654,0.116236 kka2_1:1_E142N,kka2_1:1_142,Kka2,kka2_1:1,P00552,0.116324,NO,142,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.221,-3.851,1.63,,0.471,H,A,1.52,0.85,3.626,,65.53,HAB,-2.08033,0.520039,0.00748883,0.116324 beta-lactamase_F64R,beta-lactamase_64,TEM-1,beta-lactamase,P62593,0.116356,NO,64,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-0.841,-4.158,3.317,5.70769,0.006,E,B,1.33,-0.95,,,,BHO,-0.892667,0.221079,0.000947691,0.116356 kka2_1:4_D261P,kka2_1:4_261,Kka2,kka2_1:4,P00552,0.116381,NO,261,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.708,-3.683,2.975,,0.146,G,A,0.75,-0.33,,,,HAA,-0.759333,0.168804,0.0224846,0.116381 kka2_1:4_E230I,kka2_1:4_230,Kka2,kka2_1:4,P00552,0.11655,NO,230,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.672,-3.969,1.297,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.168804,0.00920051,0.11655 kka2_1:4_V113E,kka2_1:4_113,Kka2,kka2_1:4,P00552,0.11655,NO,113,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.233,-3.887,2.654,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.168804,0.00650191,0.11655 kka2_1:4_I228Y,kka2_1:4_228,Kka2,kka2_1:4,P00552,0.116618,NO,228,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.142,-4.038,2.896,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.168804,0.00458834,0.116618 beta-lactamase_E61P,beta-lactamase_61,TEM-1,beta-lactamase,P62593,0.116636,NO,61,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.115,-3.861,1.746,6.29701,0.775,T,a,0.52,1.29,1.975,,77.62,OAA,-1.92567,0.221079,0.00440955,0.116636 beta-lactamase_625_K71Q,beta-lactamase_625_71,TEM-1,beta-lactamase_625,P62593,0.116639,NO,71,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-0.8,-3.449,2.649,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.213352,0.00103192,0.116639 kka2_1:2_G95I,kka2_1:2_95,Kka2,kka2_1:2,P00552,0.116644,NO,95,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-2.403,-3.966,1.563,,0.126,E,B,0.29,-0.74,0.359,,71.59,HOA,-2.198,0.295029,0.00743616,0.116644 kka2_1:8_G95I,kka2_1:8_95,Kka2,kka2_1:8,P00552,0.116738,NO,95,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-2.403,-3.966,1.563,,0.126,E,B,0.75,-0.74,7.774,,71.59,HOA,-2.198,0.100394,0.00743616,0.116738 kka2_1:8_G95I,kka2_1:8_95,Kka2,kka2_1:8,P00552,0.116738,NO,95,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-2.403,-3.966,1.563,,0.126,E,B,0.75,-0.74,7.774,,71.59,HOA,-2.198,0.100394,0.00743616,0.116738 kka2_1:8_L170S,kka2_1:8_170,Kka2,kka2_1:8,P00552,0.116738,NO,170,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.28,-3.627,2.347,,0.029,H,A,1.59,0.11,1.453,,62.5,AHH,-1.534,0.100394,0.00730791,0.116738 kka2_1:8_L170S,kka2_1:8_170,Kka2,kka2_1:8,P00552,0.116738,NO,170,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.28,-3.627,2.347,,0.029,H,A,1.59,0.11,1.453,,62.5,AHH,-1.534,0.100394,0.00730791,0.116738 beta-lactamase_2500_V259D,beta-lactamase_2500_259,TEM-1,beta-lactamase_2500,P62593,0.116752,NO,259,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.361275,0.0070773,0.116752 Pab1_A182H,Pab1_182,Pab1,Pab1,P04147,0.116799,NO,182,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.013,-4.497,3.484,,,H,A,0.17,0.79,,,,AHH,-1.36067,0.175299,0.000289034,0.116799 beta-lactamase_2500_C121R,beta-lactamase_2500_121,TEM-1,beta-lactamase_2500,P62593,0.11683,NO,121,C,R,CR,Special,PositiveCharge,5.07,6.34148,1.27148,180,121,174,53,108.5,173.4,64.9,-0.953,-2.762,1.809,,,H,A,0.46,-0.81,1.174,,63.29,HOP,-1.46767,0.361275,0.000744322,0.11683 kka2_1:4_A222H,kka2_1:4_222,Kka2,kka2_1:4,P00552,0.116867,NO,222,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.725,-4.708,3.983,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.168804,0.00207657,0.116867 hsp90_A587M,hsp90_587,hsp90,hsp90,P02829,0.116893,NO,587,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.456,-3.858,0,4.91216,0.049,H,A,0.55,-0.02,,,,PHP,-2.757,0.368192,0.000222939,0.116893 beta-lactamase_2500_G243Y,beta-lactamase_2500_243,TEM-1,beta-lactamase_2500,P62593,0.116911,NO,243,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.361275,0.00464034,0.116911 beta-lactamase_2500_W288C,beta-lactamase_2500_288,TEM-1,beta-lactamase_2500,P62593,0.116942,NO,288,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,,,,,,,,,,,,,BHO,,0.361275,,0.116942 beta-lactamase_M1A,beta-lactamase_1,TEM-1,beta-lactamase,P62593,0.116976,NO,1,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.998,-2.759,0.761,,,,,,,,,,OHP,-1.97,0.221079,0.00162771,0.116976 beta-lactamase_2500_M184H,beta-lactamase_2500_184,TEM-1,beta-lactamase_2500,P62593,0.116983,NO,184,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.593,-4.818,3.225,,,H,A,0.55,-0.87,2.893,,62.94,HHH,-1.41,0.361275,0.00356019,0.116983 beta-lactamase_2500_G234N,beta-lactamase_2500_234,TEM-1,beta-lactamase_2500,P62593,0.117083,NO,234,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.62,-3.448,2.828,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.361275,0.000889577,0.117083 beta-lactamase_156_L188P,beta-lactamase_156_188,TEM-1,beta-lactamase_156,P62593,0.117122,NO,188,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.166,-4.109,2.943,,,H,A,0.55,-0.3,1.574,,60.14,PHB,-1.47033,0.111618,0.00295687,0.117122 PSD95pdz3_G329R,PSD95pdz3_329,PSD95pdz3,PSD95pdz3,P31016,0.117155,NO,329,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.008,-3.615,2.607,4.7671,,,,,19.7075,,,,HOO,-1.16033,0.0758425,0.000974577,0.117155 beta-lactamase_625_T179Q,beta-lactamase_625_179,TEM-1,beta-lactamase_625,P62593,0.117188,NO,179,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.085,-3.906,2.821,,,E,B,0.22,-1.38,0.367,,73.08,PPH,-1.557,0.213352,0.00226045,0.117188 beta-lactamase_625_G243Q,beta-lactamase_625_243,TEM-1,beta-lactamase_625,P62593,0.117212,NO,243,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.213352,0.00464034,0.117212 kka2_1:8_C31I,kka2_1:8_31,Kka2,kka2_1:8,P00552,0.117222,NO,31,C,I,CI,Special,Hydrophobic,5.07,6.02,0.95,198,121,131,10,108.5,166.7,58.2,-2.246,-3.907,1.661,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.100394,0.00681582,0.117222 kka2_1:8_C31I,kka2_1:8_31,Kka2,kka2_1:8,P00552,0.117222,NO,31,C,I,CI,Special,Hydrophobic,5.07,6.02,0.95,198,121,131,10,108.5,166.7,58.2,-2.246,-3.907,1.661,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.100394,0.00681582,0.117222 beta-lactamase_39_M67P,beta-lactamase_39_67,TEM-1,beta-lactamase_39,P62593,0.117228,NO,67,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-2.231,-4.072,1.841,,0.006,G,P,0.55,-0.81,1.463,,65.03,HHP,-1.502,0.0495842,0.00409753,0.117228 beta-lactamase_2500_I229H,beta-lactamase_2500_229,TEM-1,beta-lactamase_2500,P62593,0.117433,NO,229,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.267,-4.969,3.702,,0.083,E,B,0.48,-0.76,3.875,,50,HHH,-1.58767,0.361275,0.00477249,0.117433 beta-lactamase_2500_C75Y,beta-lactamase_2500_75,TEM-1,beta-lactamase_2500,P62593,0.117444,NO,75,C,Y,CY,Special,Hydrophobic,5.07,5.66,0.59,194,121,181,60,108.5,193.6,85.1,-1.245,-4.265,3.02,,,H,A,0.46,-0.87,0.844,,50,HOO,-1.24333,0.361275,0.0034616,0.117444 beta-lactamase_2500_Y44A,beta-lactamase_2500_44,TEM-1,beta-lactamase_2500,P62593,0.117444,NO,44,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-2.547,-2.301,-0.246,,,E,B,0.21,-0.45,2.184,,73.78,OHH,-1.86267,0.361275,0.00426364,0.117444 beta-lactamase_39_T158R,beta-lactamase_39_158,TEM-1,beta-lactamase_39,P62593,0.117459,NO,158,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.116,-3.803,2.687,,0.036,,B,0.22,-0.85,2.755,,69.58,HPB,-1.269,0.0495842,0.00341825,0.117459 beta-lactamase_0_E195Y,beta-lactamase_0_195,TEM-1,beta-lactamase_0,P62593,0.117592,NO,195,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.186,-4.374,2.188,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.0500837,0.00496565,0.117592 beta-lactamase_39_A246R,beta-lactamase_39_246,TEM-1,beta-lactamase_39,P62593,0.117597,NO,246,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.121,-4.154,2.033,,0.01,E,B,0.46,-1.01,1.331,,73.78,HHH,-1.55633,0.0495842,0.00569458,0.117597 kka2_1:1_F240W,kka2_1:1_240,Kka2,kka2_1:1,P00552,0.117598,NO,240,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-0.911,-4.558,3.647,,,H,A,1.62,-1.21,5.798,,50.38,BHH,-1.67267,0.520039,0.00552543,0.117598 beta-lactamase_2500_G43Q,beta-lactamase_2500_43,TEM-1,beta-lactamase_2500,P62593,0.117613,NO,43,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.62,-4.124,3.504,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.361275,0.00120151,0.117613 kka2_1:8_P194W,kka2_1:8_194,Kka2,kka2_1:8,P00552,0.117705,NO,194,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.846,-5.598,4.752,,0.308,G,A,0.52,-1.19,4.861,,53.03,HOP,-0.888333,0.100394,0.00314194,0.117705 kka2_1:8_P194W,kka2_1:8_194,Kka2,kka2_1:8,P00552,0.117705,NO,194,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.846,-5.598,4.752,,0.308,G,A,0.52,-1.19,4.861,,53.03,HOP,-0.888333,0.100394,0.00314194,0.117705 kka2_1:8_R145I,kka2_1:8_145,Kka2,kka2_1:8,P00552,0.117705,NO,145,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.804,-4.111,2.307,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.100394,0.00846663,0.117705 kka2_1:8_R145I,kka2_1:8_145,Kka2,kka2_1:8,P00552,0.117705,NO,145,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.804,-4.111,2.307,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.100394,0.00846663,0.117705 beta-lactamase_2500_T179W,beta-lactamase_2500_179,TEM-1,beta-lactamase_2500,P62593,0.117716,NO,179,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.085,-5.211,4.126,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.361275,0.00226045,0.117716 kka2_1:1_M197W,kka2_1:1_197,Kka2,kka2_1:1,P00552,0.117785,NO,197,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.707,-5.268,3.561,,0.121,E,B,1.59,-1.19,2.097,,65.53,HHH,-1.847,0.520039,0.00921295,0.117785 beta-lactamase_156_L205K,beta-lactamase_156_205,TEM-1,beta-lactamase_156,P62593,0.117788,NO,205,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.922,-3.736,2.814,,,H,A,0.55,-0.46,0.678,,42.31,PHH,-1.57767,0.111618,0.00255802,0.117788 beta-lactamase_625_G281D,beta-lactamase_625_281,TEM-1,beta-lactamase_625,P62593,0.117847,NO,281,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.213352,0.0406482,0.117847 beta-lactamase_2500_S128V,beta-lactamase_2500_128,TEM-1,beta-lactamase_2500,P62593,0.117874,NO,128,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-0.84,-3.529,2.689,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.361275,0.00071483,0.117874 beta-lactamase_2500_I229P,beta-lactamase_2500_229,TEM-1,beta-lactamase_2500,P62593,0.118065,NO,229,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.267,-4.079,2.812,,0.083,E,B,0.48,-0.76,3.875,,50,HHH,-1.58767,0.361275,0.00477249,0.118065 beta-lactamase_A124E,beta-lactamase_124,TEM-1,beta-lactamase,P62593,0.118076,NO,124,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.181,-3.544,2.363,4.58507,,H,A,0.58,-0.9,2.273,,64.34,HHH,-1.152,0.221079,0.00481399,0.118076 beta-lactamase_2500_S104E,beta-lactamase_2500_104,TEM-1,beta-lactamase_2500,P62593,0.118161,NO,104,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.015,-3.366,2.351,,0.04,,b,0.27,0.57,1.133,,63.29,HPO,-1.05267,0.361275,0.00218083,0.118161 beta-lactamase_625_G234R,beta-lactamase_625_234,TEM-1,beta-lactamase_625,P62593,0.118175,NO,234,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.62,-3.933,3.313,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.213352,0.000889577,0.118175 beta-lactamase_2500_G43I,beta-lactamase_2500_43,TEM-1,beta-lactamase_2500,P62593,0.118286,NO,43,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.62,-4.235,3.615,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.361275,0.00120151,0.118286 kka2_1:4_T187L,kka2_1:4_187,Kka2,kka2_1:4,P00552,0.118342,NO,187,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.273,-3.26,1.987,,0.007,E,B,0.22,-0.85,2.73,,52.27,HPB,-1.06567,0.168804,0.00693073,0.118342 kka2_1:1_R253F,kka2_1:1_253,Kka2,kka2_1:1,P00552,0.118374,NO,253,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.356,-4.389,3.033,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.520039,0.0144195,0.118374 beta-lactamase_V31Y,beta-lactamase_31,TEM-1,beta-lactamase,P62593,0.118447,NO,31,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.822,-4.027,2.205,5.43781,,H,A,2.78,-0.46,2.885,,73.78,BHB,-2.03767,0.221079,0.00478065,0.118447 beta-lactamase_2500_I258H,beta-lactamase_2500_258,TEM-1,beta-lactamase_2500,P62593,0.118473,NO,258,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.361275,0.007931,0.118473 E1_Ubiquitin_R72E,E1_Ubiquitin_72,Uba1,E1_Ubiquitin,P0CG63,0.118479,NO,72,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.184,-3.032,1.848,,0.077,,B,0.16,-0.1,,,,HBH,-1.08733,0.18783,0.00129853,0.118479 beta-lactamase_2500_D177I,beta-lactamase_2500_177,TEM-1,beta-lactamase_2500,P62593,0.118503,NO,177,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.967,-4.048,3.081,,0.006,T,L,0.75,-1.02,4.131,,64.69,BAP,-0.873667,0.361275,0.000864022,0.118503 beta-lactamase_625_V42D,beta-lactamase_625_42,TEM-1,beta-lactamase_625,P62593,0.118531,NO,42,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.564,-4.059,2.495,,0.017,E,B,0.44,-0.51,2.576,,63.99,BHO,-1.042,0.213352,0.00404515,0.118531 kka2_1:1_P194H,kka2_1:1_194,Kka2,kka2_1:1,P00552,0.118716,NO,194,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.846,-4.708,3.862,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.520039,0.00314194,0.118716 kka2_1:1_F203I,kka2_1:1_203,Kka2,kka2_1:1,P00552,0.118782,NO,203,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-0.911,-3.319,2.408,,0.26,E,B,0.58,-0.92,7.323,,63.64,BHP,-1.34167,0.520039,0.00318738,0.118782 beta-lactamase_2500_C121F,beta-lactamase_2500_121,TEM-1,beta-lactamase_2500,P62593,0.118794,NO,121,C,F,CF,Special,Hydrophobic,5.07,3.32051,-1.74949,205,121,165,44,108.5,189.9,81.4,-0.953,-4.116,3.163,,,H,A,0.46,-0.81,1.174,,63.29,HOP,-1.46767,0.361275,0.000744322,0.118794 beta-lactamase_2500_G236Y,beta-lactamase_2500_236,TEM-1,beta-lactamase_2500,P62593,0.118859,NO,236,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.784,-4.387,3.603,,0.241,,b,0.29,-0.59,2.14,,64.69,HOO,-1.025,0.361275,0.00162372,0.118859 kka2_1:4_L223H,kka2_1:4_223,Kka2,kka2_1:4,P00552,0.118987,NO,223,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.861,-4.978,4.117,,,H,A,1.59,-1.24,1.268,,50,HHH,-0.854333,0.168804,0.00253574,0.118987 beta-lactamase_2500_S68Y,beta-lactamase_2500_68,TEM-1,beta-lactamase_2500,P62593,0.119002,NO,68,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-0.913,-4.188,3.275,,0.064,G,A,0.27,-1.03,2.824,,64.69,HPP,-1.37233,0.361275,0.000800065,0.119002 beta-lactamase_I259N,beta-lactamase_259,TEM-1,beta-lactamase,P62593,0.119022,NO,259,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.522,-4.142,2.62,5.28457,,E,B,1,-0.8,1.24,,64.34,HHH,-1.53267,0.221079,0.0070773,0.119022 beta-lactamase_T107Q,beta-lactamase_107,TEM-1,beta-lactamase,P62593,0.119022,NO,107,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.117,-3.889,2.772,5.23432,,G,A,2.12,-0.06,3.676,,67.83,HPA,-1.265,0.221079,0.00239347,0.119022 beta-lactamase_0_V117A,beta-lactamase_0_117,TEM-1,beta-lactamase_0,P62593,0.119031,NO,117,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.53,-3.142,1.612,,,H,A,0.44,-0.34,1.16,,65.03,PHB,-1.741,0.0500837,0.00467906,0.119031 beta-lactamase_2500_T147F,beta-lactamase_2500_147,TEM-1,beta-lactamase_2500,P62593,0.119045,NO,147,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.149,-4.147,2.998,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.361275,0.00226017,0.119045 kka2_1:1_T187C,kka2_1:1_187,Kka2,kka2_1:1,P00552,0.119066,NO,187,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.273,-2.642,1.369,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.520039,0.00693073,0.119066 beta-lactamase_2500_K32P,beta-lactamase_2500_32,TEM-1,beta-lactamase_2500,P62593,0.119075,NO,32,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.984,-3.947,1.963,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.361275,0.00401283,0.119075 beta-lactamase_2500_V31E,beta-lactamase_2500_31,TEM-1,beta-lactamase_2500,P62593,0.119102,NO,31,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.822,-3.908,2.086,,,H,A,0.44,-0.46,0.955,,73.78,BHB,-2.03767,0.361275,0.00478065,0.119102 kka2_1:4_S105N,kka2_1:4_105,Kka2,kka2_1:4,P00552,0.119115,NO,105,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.945,-3.821,1.876,,0.056,S,B,0.77,-1.04,3.442,,65.53,PPB,-2.17033,0.168804,0.00847233,0.119115 Pab1_F173T,Pab1_173,Pab1,Pab1,P04147,0.11916,NO,173,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.477,-3.535,2.058,,,E,B,0.87,-0.16,1.636,,63.26,BHA,-1.36967,0.175299,0.00148779,0.11916 beta-lactamase_P181N,beta-lactamase_181,TEM-1,beta-lactamase,P62593,0.119206,NO,181,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.813,-3.924,3.111,5.14752,,H,A,1.1,-1.14,1.357,,61.54,HOH,-1.795,0.221079,0.000703122,0.119206 PSD95pdz3_I388D,PSD95pdz3_388,PSD95pdz3,PSD95pdz3,P31016,0.119336,NO,388,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.63,-3.6,1.97,5.17282,,,,,16.0025,,,,PHH,-1.54967,0.0758425,0.000151216,0.119336 beta-lactamase_2500_N134M,beta-lactamase_2500_134,TEM-1,beta-lactamase_2500,P62593,0.119488,NO,134,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-0.879,-4.702,3.823,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.361275,0.000644786,0.119488 beta-lactamase_I45K,beta-lactamase_45,TEM-1,beta-lactamase,P62593,0.119519,NO,45,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-2.421,-3.76,1.339,5.31505,,E,B,1,-0.3,2.256,,77.62,HHA,-2.30267,0.221079,0.00452842,0.119519 PSD95pdz3_D357P,PSD95pdz3_357,PSD95pdz3,PSD95pdz3,P31016,0.119772,NO,357,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.264,-3.336,2.072,5.22306,,,,,10.975,,,,OAP,-1.32367,0.0758425,0.000609015,0.119772 beta-lactamase_2500_V260F,beta-lactamase_2500_260,TEM-1,beta-lactamase_2500,P62593,0.119892,NO,260,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.361275,0.00471757,0.119892 kka2_1:2_R211T,kka2_1:2_211,Kka2,kka2_1:2,P00552,0.119893,NO,211,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-0.899,-3.493,2.594,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.295029,0.00204888,0.119893 beta-lactamase_39_D177R,beta-lactamase_39_177,TEM-1,beta-lactamase_39,P62593,0.119902,NO,177,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.967,-3.931,2.964,,0.006,T,L,0.75,-1.02,3.536,,64.69,BAP,-0.873667,0.0495842,0.000864022,0.119902 Pab1_I128R,Pab1_128,Pab1,Pab1,P04147,0.119928,NO,128,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.345,-4.051,2.706,,0.008,E,B,1.68,-0.6,1.706,,78.68,PHH,-1.231,0.175299,0.00104192,0.119928 beta-lactamase_2500_G43F,beta-lactamase_2500_43,TEM-1,beta-lactamase_2500,P62593,0.119935,NO,43,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.62,-4.292,3.672,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.361275,0.00120151,0.119935 beta-lactamase_2500_A185N,beta-lactamase_2500_185,TEM-1,beta-lactamase_2500,P62593,0.11994,NO,185,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.406,-4.005,2.599,,,H,A,0.46,-1.02,2.999,,65.03,HHP,-1.84033,0.361275,0.00467449,0.11994 beta-lactamase_625_C75D,beta-lactamase_625_75,TEM-1,beta-lactamase_625,P62593,0.120001,NO,75,C,D,CD,Special,negativeCharge,5.07,5.0516,-0.0184,154,121,133,12,108.5,111.1,2.6,-1.245,-3.832,2.587,,,H,A,0.46,-0.87,2.141,,50,HOO,-1.24333,0.213352,0.0034616,0.120001 beta-lactamase_2500_S68H,beta-lactamase_2500_68,TEM-1,beta-lactamase_2500,P62593,0.120041,NO,68,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-0.913,-4.418,3.505,,0.064,G,A,0.27,-1.03,2.824,,64.69,HPP,-1.37233,0.361275,0.000800065,0.120041 kka2_1:1_A191M,kka2_1:1_191,Kka2,kka2_1:1,P00552,0.12009,NO,191,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.831,-4.572,3.741,,,.,b,0.46,-0.94,0.53,,50,AHO,-0.868667,0.520039,0.00338807,0.12009 kka2_1:1_N200H,kka2_1:1_200,Kka2,kka2_1:1,P00552,0.120171,NO,200,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-2.446,-3.247,0.801,,0.756,T,L,0.61,-0.08,17.299,17.299,64.39,APO,-2.08,0.520039,0.00838549,0.120171 beta-lactamase_2500_E164V,beta-lactamase_2500_164,TEM-1,beta-lactamase_2500,P62593,0.120198,NO,164,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-0.948,-3.599,2.651,,0.011,T,B,1.04,-0.4,0.352,,64.69,HAO,-1.388,0.361275,0.00137286,0.120198 beta-lactamase_Y260N,beta-lactamase_260,TEM-1,beta-lactamase,P62593,0.120244,NO,260,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-1.101,-4.032,2.931,5.50878,,E,B,0.73,-1.04,0.865,,60.49,HHP,-1.83433,0.221079,0.00471757,0.120244 kka2_1:4_G213E,kka2_1:4_213,Kka2,kka2_1:4,P00552,0.120256,NO,213,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.596,-3.693,3.097,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.168804,0.00187654,0.120256 kka2_1:1_A78L,kka2_1:1_78,Kka2,kka2_1:1,P00552,0.12034,NO,78,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.744,-3.506,1.762,,0.078,.,B,0.46,-0.53,0.206,,56.06,OHH,-1.863,0.520039,0.00457299,0.12034 kka2_1:1_L223S,kka2_1:1_223,Kka2,kka2_1:1,P00552,0.120358,NO,223,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.861,-3.684,2.823,,,H,A,0.55,-1.24,1.268,,50,HHH,-0.854333,0.520039,0.00253574,0.120358 beta-lactamase_2500_P181N,beta-lactamase_2500_181,TEM-1,beta-lactamase_2500,P62593,0.120377,NO,181,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.813,-3.924,3.111,,,H,A,0.52,-1.14,1.946,,61.54,HOH,-1.795,0.361275,0.000703122,0.120377 beta-lactamase_156_A246R,beta-lactamase_156_246,TEM-1,beta-lactamase_156,P62593,0.120383,NO,246,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.121,-4.154,2.033,,0.01,E,B,0.46,-1.01,1.959,,73.78,HHH,-1.55633,0.111618,0.00569458,0.120383 kka2_1:1_D183L,kka2_1:1_183,Kka2,kka2_1:1,P00552,0.120409,NO,183,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.204,-3.71,2.506,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.520039,0.00426304,0.120409 beta-lactamase_0_V117T,beta-lactamase_0_117,TEM-1,beta-lactamase_0,P62593,0.120423,NO,117,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.53,-3.486,1.956,,,H,A,0.44,-0.34,1.16,,65.03,PHB,-1.741,0.0500837,0.00467906,0.120423 beta-lactamase_156_N168F,beta-lactamase_156_168,TEM-1,beta-lactamase_156,P62593,0.120507,NO,168,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-1.029,-4.27,3.241,,0.113,G,A,0.61,-0.4,1.014,,44.41,HPA,-1.13233,0.111618,0.00288667,0.120507 beta-lactamase_625_I261P,beta-lactamase_625_261,TEM-1,beta-lactamase_625,P62593,0.120533,NO,261,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.213352,0.0123091,0.120533 kka2_1:8_T187P,kka2_1:8_187,Kka2,kka2_1:8,P00552,0.120589,NO,187,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.273,-3.887,2.614,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.100394,0.00693073,0.120589 kka2_1:8_T187P,kka2_1:8_187,Kka2,kka2_1:8,P00552,0.120589,NO,187,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.273,-3.887,2.614,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.100394,0.00693073,0.120589 kka2_1:1_A176K,kka2_1:1_176,Kka2,kka2_1:1,P00552,0.120608,NO,176,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.621,-2.698,1.077,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.520039,0.0083587,0.120608 kka2_1:4_L260H,kka2_1:4_260,Kka2,kka2_1:4,P00552,0.120632,NO,260,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.741,-4.933,4.192,,0.022,H,A,0.55,-0.52,,,,HHA,-0.845667,0.168804,0.0233782,0.120632 kka2_1:2_R121P,kka2_1:2_121,Kka2,kka2_1:2,P00552,0.120656,NO,121,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.552,-4.003,2.451,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.295029,0.00523326,0.120656 kka2_1:4_A215M,kka2_1:4_215,Kka2,kka2_1:4,P00552,0.12071,NO,215,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.968,-4.593,3.625,,0.039,E,B,0.46,-0.59,0.754,,50.38,HHA,-1.00467,0.168804,0.00529129,0.12071 beta-lactamase_625_G142I,beta-lactamase_625_142,TEM-1,beta-lactamase_625,P62593,0.120728,NO,142,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.707,-4.199,3.492,,0.034,,p,0.29,-0.64,1.35,,64.69,OOO,-0.834,0.213352,0.00060149,0.120728 kka2_1:4_I221W,kka2_1:4_221,Kka2,kka2_1:4,P00552,0.120736,NO,221,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.739,-3.219,1.48,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.168804,0.00945908,0.120736 kka2_1:1_D33I,kka2_1:1_33,Kka2,kka2_1:1,P00552,0.120785,NO,33,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.186,-4.175,1.989,,0.561,S,A,0.75,3.35,2.568,,71.59,PAH,-1.306,0.520039,0.00633568,0.120785 beta-lactamase_39_A132W,beta-lactamase_39_132,TEM-1,beta-lactamase_39,P62593,0.120831,NO,132,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.9,-5.372,4.472,,,H,A,0.46,-0.93,8.408,,64.69,PHH,-1.138,0.0495842,0.000962524,0.120831 kka2_1:4_G99W,kka2_1:4_99,Kka2,kka2_1:4,P00552,0.120847,NO,99,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.596,-5.126,4.53,,0.368,S,g,0.29,-0.87,,,,OOP,-1.63067,0.168804,0.00186055,0.120847 beta-lactamase_39_E164Q,beta-lactamase_39_164,TEM-1,beta-lactamase_39,P62593,0.120903,NO,164,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-0.948,-3.358,2.41,,0.011,T,B,1.04,-0.4,0.664,,64.69,HAO,-1.388,0.0495842,0.00137286,0.120903 kka2_1:1_I115H,kka2_1:1_115,Kka2,kka2_1:1,P00552,0.120923,NO,115,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.606,-5.024,3.418,,0.105,H,A,0.48,-1.18,0.878,,65.53,PHH,-2.205,0.520039,0.00836567,0.120923 Ubiquitin_G76H,Ubiquitin_76,Uba1,Ubiquitin,P0CG48,0.120968,NO,76,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.651,-3.315,1.664,5.7647,0.23,,B,0.12,0.08,9.665,9.665,34.31,OOO,-1.632,0.205827,0.000653872,0.120968 Ubiquitin_I44H,Ubiquitin_44,Uba1,Ubiquitin,P0CG48,0.120968,NO,44,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.566,-3.086,1.52,4.71256,,E,B,0.27,-1.17,5.26,,39.71,HHH,-1.38567,0.205827,0.000613305,0.120968 Ubiquitin_K48E,Ubiquitin_48,Uba1,Ubiquitin,P0CG48,0.120968,NO,48,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.436,-2.31,0.874,5.03072,0.132,E,B,2.92,-0.28,1.539,,53.87,OBP,-1.6,0.205827,0.000394633,0.120968 Ubiquitin_R42W,Ubiquitin_42,Uba1,Ubiquitin,P0CG48,0.120968,NO,42,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.571,-3.118,1.547,5.07805,0.244,E,B,0.68,-0.54,1.976,,72.85,PBH,-1.38967,0.205827,0.000622265,0.120968 Ubiquitin_T7Y,Ubiquitin_7,Uba1,Ubiquitin,P0CG48,0.120968,NO,7,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.415,-4.188,2.773,4.954,0.094,E,B,0.43,-0.78,0.805,,21.31,BPH,-1.41033,0.205827,0.000647855,0.120968 beta-lactamase_2500_Y44E,beta-lactamase_2500_44,TEM-1,beta-lactamase_2500,P62593,0.120977,NO,44,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-2.547,-3.866,1.319,,,E,B,0.21,-0.45,2.184,,73.78,OHH,-1.86267,0.361275,0.00426364,0.120977 beta-lactamase_625_G43R,beta-lactamase_625_43,TEM-1,beta-lactamase_625,P62593,0.120984,NO,43,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.62,-3.933,3.313,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.213352,0.00120151,0.120984 beta-lactamase_156_L188R,beta-lactamase_156_188,TEM-1,beta-lactamase_156,P62593,0.121015,NO,188,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.166,-3.976,2.81,,,H,A,0.55,-0.3,1.574,,60.14,PHB,-1.47033,0.111618,0.00295687,0.121015 beta-lactamase_625_A132I,beta-lactamase_625_132,TEM-1,beta-lactamase_625,P62593,0.121018,NO,132,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.9,-3.489,2.589,,,H,A,0.46,-0.93,0.316,,64.69,PHH,-1.138,0.213352,0.000962524,0.121018 kka2_1:1_V198D,kka2_1:1_198,Kka2,kka2_1:1,P00552,0.121044,NO,198,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.719,-3.799,2.08,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.520039,0.00835002,0.121044 kka2_1:4_V185N,kka2_1:4_185,Kka2,kka2_1:4,P00552,0.121082,NO,185,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.045,-4.197,3.152,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.168804,0.00367031,0.121082 beta-lactamase_2500_M67K,beta-lactamase_2500_67,TEM-1,beta-lactamase_2500,P62593,0.121202,NO,67,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-2.231,-3.7,1.469,,0.006,G,P,0.55,-0.81,2.653,,65.03,HHP,-1.502,0.361275,0.00409753,0.121202 kka2_1:2_V113Q,kka2_1:2_113,Kka2,kka2_1:2,P00552,0.121204,NO,113,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.233,-4.296,3.063,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.295029,0.00650191,0.121204 beta-lactamase_156_L146R,beta-lactamase_156_146,TEM-1,beta-lactamase_156,P62593,0.121212,NO,146,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.462,-4.192,2.73,,0.007,H,A,0.55,-0.56,1.578,,64.69,AHP,-1.656,0.111618,0.00474542,0.121212 kka2_1:1_P179D,kka2_1:1_179,Kka2,kka2_1:1,P00552,0.121259,NO,179,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.974,-3.655,2.681,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.520039,0.00298346,0.121259 kka2_1:2_P128E,kka2_1:2_128,Kka2,kka2_1:2,P00552,0.121304,NO,128,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.922,-3.892,1.97,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.295029,0.00774689,0.121304 kka2_1:8_E63Y,kka2_1:8_63,Kka2,kka2_1:8,P00552,0.121306,NO,63,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-0.762,-4.191,3.429,,0.043,H,A,1.52,-0.43,,,,AAH,-1.283,0.100394,0.00118399,0.121306 kka2_1:8_E63Y,kka2_1:8_63,Kka2,kka2_1:8,P00552,0.121306,NO,63,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-0.762,-4.191,3.429,,0.043,H,A,1.52,-0.43,,,,AAH,-1.283,0.100394,0.00118399,0.121306 beta-lactamase_156_K232F,beta-lactamase_156_232,TEM-1,beta-lactamase_156,P62593,0.121327,NO,232,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.012,-4.334,3.322,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.111618,0.00313441,0.121327 kka2_1:4_I115S,kka2_1:4_115,Kka2,kka2_1:4,P00552,0.121333,NO,115,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.606,-2.994,1.388,,0.105,H,A,1.52,-1.18,9.996,9.996,65.53,PHH,-2.205,0.168804,0.00836567,0.121333 beta-lactamase_625_S68L,beta-lactamase_625_68,TEM-1,beta-lactamase_625,P62593,0.121334,NO,68,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-0.913,-3.407,2.494,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.213352,0.000800065,0.121334 beta-lactamase_2500_G249N,beta-lactamase_2500_249,TEM-1,beta-lactamase_2500,P62593,0.121341,NO,249,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.312,,,,0.256,S,B,0.23,0.04,30.841,30.841,72.73,HOO,-1.81367,0.361275,0.00220169,0.121341 beta-lactamase_625_A185R,beta-lactamase_625_185,TEM-1,beta-lactamase_625,P62593,0.121411,NO,185,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.406,-3.963,2.557,,,H,A,0.46,-1.02,0.365,,65.03,HHP,-1.84033,0.213352,0.00467449,0.121411 beta-lactamase_625_S128Y,beta-lactamase_625_128,TEM-1,beta-lactamase_625,P62593,0.121414,NO,128,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-0.84,-4.162,3.322,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.213352,0.00071483,0.121414 kka2_1:4_F48R,kka2_1:4_48,Kka2,kka2_1:4,P00552,0.12142,NO,48,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.453,-4.265,2.812,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.168804,0.00475422,0.12142 beta-lactamase_2500_N130F,beta-lactamase_2500_130,TEM-1,beta-lactamase_2500,P62593,0.121434,NO,130,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-0.798,-4.292,3.494,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.361275,0.000683376,0.121434 beta-lactamase_156_D177I,beta-lactamase_156_177,TEM-1,beta-lactamase_156,P62593,0.121443,NO,177,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.967,-4.048,3.081,,0.006,T,L,0.75,-1.02,2.072,,64.69,BAP,-0.873667,0.111618,0.000864022,0.121443 beta-lactamase_M184E,beta-lactamase_184,TEM-1,beta-lactamase,P62593,0.121465,NO,184,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.593,-3.708,2.115,5.39575,,H,A,1.3,-0.87,2.893,,62.94,HHH,-1.41,0.221079,0.00356019,0.121465 kka2_1:1_Q252M,kka2_1:1_252,Kka2,kka2_1:1,P00552,0.121489,NO,252,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.63,-4.83,2.2,,0.906,H,A,0.64,0.35,1.369,,92.05,PPB,-2.20733,0.520039,0.0121001,0.121489 beta-lactamase_2500_L205P,beta-lactamase_2500_205,TEM-1,beta-lactamase_2500,P62593,0.121577,NO,205,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.922,-4.159,3.237,,,H,A,0.55,-0.46,0.831,,42.31,PHH,-1.57767,0.361275,0.00255802,0.121577 beta-lactamase_2500_W288S,beta-lactamase_2500_288,TEM-1,beta-lactamase_2500,P62593,0.121692,NO,288,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,,,,,,,,,,,,,BHO,,0.361275,,0.121692 kka2_1:1_Q100W,kka2_1:1_100,Kka2,kka2_1:1,P00552,0.121843,NO,100,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.77,-5.568,2.798,,0.646,E,B,0.4,-0.79,15.116,15.116,71.59,OPA,-1.46467,0.520039,0.0066405,0.121843 beta-lactamase_156_I125W,beta-lactamase_156_125,TEM-1,beta-lactamase_156,P62593,0.12186,NO,125,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.441,-5.341,3.9,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.111618,0.00383964,0.12186 kka2_1:2_L92E,kka2_1:2_92,Kka2,kka2_1:2,P00552,0.121883,NO,92,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.893,-3.919,3.026,,0.007,E,B,1.59,-0.19,1.447,,63.26,HHH,-0.962,0.295029,0.00307177,0.121883 kka2_1:1_E230I,kka2_1:1_230,Kka2,kka2_1:1,P00552,0.121993,NO,230,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.672,-3.969,1.297,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.520039,0.00920051,0.121993 kka2_1:2_D208R,kka2_1:2_208,Kka2,kka2_1:2,P00552,0.122021,NO,208,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.708,-3.961,3.253,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.295029,0.00212588,0.122021 kka2_1:8_L92E,kka2_1:8_92,Kka2,kka2_1:8,P00552,0.122022,NO,92,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.893,-3.919,3.026,,0.007,E,B,1.59,-0.19,1.719,,63.26,HHH,-0.962,0.100394,0.00307177,0.122022 kka2_1:8_L92E,kka2_1:8_92,Kka2,kka2_1:8,P00552,0.122022,NO,92,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.893,-3.919,3.026,,0.007,E,B,1.59,-0.19,1.719,,63.26,HHH,-0.962,0.100394,0.00307177,0.122022 beta-lactamase_39_V260P,beta-lactamase_39_260,TEM-1,beta-lactamase_39,P62593,0.122033,NO,260,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.0495842,0.00471757,0.122033 beta-lactamase_156_S241W,beta-lactamase_156_241,TEM-1,beta-lactamase_156,P62593,0.122166,NO,241,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.111618,0.00452736,0.122166 beta-lactamase_625_D177H,beta-lactamase_625_177,TEM-1,beta-lactamase_625,P62593,0.122195,NO,177,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.967,-4.511,3.544,,0.006,T,L,0.75,-1.02,1.333,,64.69,BAP,-0.873667,0.213352,0.000864022,0.122195 kka2_1:2_V214D,kka2_1:2_214,Kka2,kka2_1:2,P00552,0.122206,NO,214,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.261,-4.099,2.838,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.295029,0.00692782,0.122206 kka2_1:8_W91I,kka2_1:8_91,Kka2,kka2_1:8,P00552,0.12226,NO,91,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-1.178,-3.942,2.764,,0.077,E,B,1.51,0.27,2.51,,48.48,AHH,-1.51,0.100394,0.00358653,0.12226 kka2_1:8_W91I,kka2_1:8_91,Kka2,kka2_1:8,P00552,0.12226,NO,91,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-1.178,-3.942,2.764,,0.077,E,B,1.51,0.27,2.51,,48.48,AHH,-1.51,0.100394,0.00358653,0.12226 kka2_1:8_W91N,kka2_1:8_91,Kka2,kka2_1:8,P00552,0.12226,NO,91,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-1.178,-4.186,3.008,,0.077,E,B,1.51,0.27,2.51,,48.48,AHH,-1.51,0.100394,0.00358653,0.12226 kka2_1:8_W91N,kka2_1:8_91,Kka2,kka2_1:8,P00552,0.12226,NO,91,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-1.178,-4.186,3.008,,0.077,E,B,1.51,0.27,2.51,,48.48,AHH,-1.51,0.100394,0.00358653,0.12226 beta-lactamase_625_K71H,beta-lactamase_625_71,TEM-1,beta-lactamase_625,P62593,0.122261,NO,71,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-0.8,-4.455,3.655,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.213352,0.00103192,0.122261 beta-lactamase_G142I,beta-lactamase_142,TEM-1,beta-lactamase,P62593,0.12228,NO,142,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.707,-4.199,3.492,4.55474,0.034,,p,0.77,-0.64,1.947,,64.69,OOO,-0.834,0.221079,0.00060149,0.12228 kka2_1:2_G245E,kka2_1:2_245,Kka2,kka2_1:2,P00552,0.122332,NO,245,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.812,-2.733,1.921,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.295029,0.00683899,0.122332 kka2_1:1_A172V,kka2_1:1_172,Kka2,kka2_1:1,P00552,0.122422,NO,172,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.757,-2.683,0.926,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.520039,0.0079265,0.122422 beta-lactamase_39_T179Q,beta-lactamase_39_179,TEM-1,beta-lactamase_39,P62593,0.122468,NO,179,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.085,-3.906,2.821,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.0495842,0.00226045,0.122468 beta-lactamase_2500_F70P,beta-lactamase_2500_70,TEM-1,beta-lactamase_2500,P62593,0.122471,NO,70,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.169,-4.211,3.042,,,H,A,0.58,-1.34,1.918,,63.99,PHB,-0.980667,0.361275,0.00193499,0.122471 kka2_1:8_F133I,kka2_1:8_133,Kka2,kka2_1:8,P00552,0.122498,NO,133,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-0.871,-3.407,2.536,,0.178,,B,1.62,0.43,1.816,,42.42,OHA,-0.871667,0.100394,0.00182168,0.122498 kka2_1:8_F133I,kka2_1:8_133,Kka2,kka2_1:8,P00552,0.122498,NO,133,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-0.871,-3.407,2.536,,0.178,,B,1.62,0.43,1.816,,42.42,OHA,-0.871667,0.100394,0.00182168,0.122498 kka2_1:2_F256D,kka2_1:2_256,Kka2,kka2_1:2,P00552,0.12254,NO,256,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.49,-4.089,2.599,,,H,A,0.58,-0.78,1.653,,53.03,HHH,-1.423,0.295029,0.0132841,0.12254 beta-lactamase_2500_Y262K,beta-lactamase_2500_262,TEM-1,beta-lactamase_2500,P62593,0.122593,NO,262,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.361275,0.00853516,0.122593 beta-lactamase_156_S68G,beta-lactamase_156_68,TEM-1,beta-lactamase_156,P62593,0.122686,NO,68,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-0.913,-2.934,2.021,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.111618,0.000800065,0.122686 kka2_1:8_Y218P,kka2_1:8_218,Kka2,kka2_1:8,P00552,0.122736,NO,218,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-1.438,-4.207,2.769,,0.122,H,A,1.25,-0.69,2.923,,56.06,BHP,-1.17533,0.100394,0.0126098,0.122736 kka2_1:8_Y218P,kka2_1:8_218,Kka2,kka2_1:8,P00552,0.122736,NO,218,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-1.438,-4.207,2.769,,0.122,H,A,1.25,-0.69,2.923,,56.06,BHP,-1.17533,0.100394,0.0126098,0.122736 beta-lactamase_625_F64S,beta-lactamase_625_64,TEM-1,beta-lactamase_625,P62593,0.122802,NO,64,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-0.841,-3.611,2.77,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.213352,0.000947691,0.122802 beta-lactamase_156_I125K,beta-lactamase_156_125,TEM-1,beta-lactamase_156,P62593,0.122825,NO,125,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.441,-3.825,2.384,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.111618,0.00383964,0.122825 kka2_1:2_F263M,kka2_1:2_263,Kka2,kka2_1:2,P00552,0.122877,NO,263,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-0.911,-4.239,3.328,,0.006,G,A,1.62,-0.12,5.275,,45.83,AHH,-0.92,0.295029,0.0172454,0.122877 beta-lactamase_2500_C75P,beta-lactamase_2500_75,TEM-1,beta-lactamase_2500,P62593,0.122879,NO,75,C,P,CP,Special,Special,5.07,6.3,1.23,169,121,115,-6,108.5,112.7,4.2,-1.245,-4.012,2.767,,,H,A,0.46,-0.87,0.844,,50,HOO,-1.24333,0.361275,0.0034616,0.122879 beta-lactamase_625_G240K,beta-lactamase_625_240,TEM-1,beta-lactamase_625,P62593,0.12291,NO,240,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.213352,0.00591201,0.12291 hsp90_W585S,hsp90_585,hsp90,hsp90,P02829,0.122937,NO,585,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-4.251,-2.764,0,5.31455,0.508,,B,1.22,0.43,,,,OHP,-3.17533,0.368192,0.000222939,0.122937 beta-lactamase_2500_G240D,beta-lactamase_2500_240,TEM-1,beta-lactamase_2500,P62593,0.123022,NO,240,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.361275,0.00591201,0.123022 beta-lactamase_2500_N168P,beta-lactamase_2500_168,TEM-1,beta-lactamase_2500,P62593,0.123041,NO,168,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-1.029,-3.858,2.829,,0.113,G,A,0.61,-0.4,2.9,,44.41,HPA,-1.13233,0.361275,0.00288667,0.123041 beta-lactamase_39_E164R,beta-lactamase_39_164,TEM-1,beta-lactamase_39,P62593,0.123089,NO,164,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-0.948,-3.511,2.563,,0.011,T,B,1.04,-0.4,0.664,,64.69,HAO,-1.388,0.0495842,0.00137286,0.123089 PSD95pdz3_L379R,PSD95pdz3_379,PSD95pdz3,PSD95pdz3,P31016,0.123138,NO,379,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.347,-3.615,2.268,5.37777,,,,,16.8762,,,,HHB,-1.35667,0.0758425,0.00029733,0.123138 kka2_1:8_I196K,kka2_1:8_196,Kka2,kka2_1:8,P00552,0.123211,NO,196,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-2.115,-3.976,1.861,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.100394,0.0107273,0.123211 kka2_1:8_I196K,kka2_1:8_196,Kka2,kka2_1:8,P00552,0.123211,NO,196,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-2.115,-3.976,1.861,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.100394,0.0107273,0.123211 kka2_1:4_D227I,kka2_1:4_227,Kka2,kka2_1:4,P00552,0.123238,NO,227,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.758,-3.917,2.159,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.168804,0.00745029,0.123238 beta-lactamase_2500_V117W,beta-lactamase_2500_117,TEM-1,beta-lactamase_2500,P62593,0.12324,NO,117,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.53,-5.228,3.698,,,H,A,0.44,-0.34,1.23,,65.03,PHB,-1.741,0.361275,0.00467906,0.12324 beta-lactamase_2500_D177K,beta-lactamase_2500_177,TEM-1,beta-lactamase_2500,P62593,0.123245,NO,177,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.967,-3.523,2.556,,0.006,T,L,0.75,-1.02,4.131,,64.69,BAP,-0.873667,0.361275,0.000864022,0.123245 beta-lactamase_2500_D174K,beta-lactamase_2500_174,TEM-1,beta-lactamase_2500,P62593,0.12326,NO,174,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.738,-3.457,2.719,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.361275,0.00125633,0.12326 kka2_1:2_W236S,kka2_1:2_236,Kka2,kka2_1:2,P00552,0.123293,NO,236,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-1.363,-3.736,2.373,,0.303,H,A,1.51,-0.76,5.58,,48.48,AHH,-1.81267,0.295029,0.0088796,0.123293 beta-lactamase_2500_G249F,beta-lactamase_2500_249,TEM-1,beta-lactamase_2500,P62593,0.123298,NO,249,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.312,,,,0.256,S,B,0.23,0.04,30.841,30.841,72.73,HOO,-1.81367,0.361275,0.00220169,0.123298 kka2_1:8_A78M,kka2_1:8_78,Kka2,kka2_1:8,P00552,0.123448,NO,78,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.744,-4.709,2.965,,0.078,,B,1.04,-0.53,1.251,,56.06,OHH,-1.863,0.100394,0.00457299,0.123448 kka2_1:8_A78M,kka2_1:8_78,Kka2,kka2_1:8,P00552,0.123448,NO,78,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.744,-4.709,2.965,,0.078,,B,1.04,-0.53,1.251,,56.06,OHH,-1.863,0.100394,0.00457299,0.123448 kka2_1:2_V186H,kka2_1:2_186,Kka2,kka2_1:2,P00552,0.123515,NO,186,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.011,-4.974,3.963,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.295029,0.00409703,0.123515 beta-lactamase_G239P,beta-lactamase_239,TEM-1,beta-lactamase,P62593,0.123549,NO,239,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.819,-3.883,3.064,4.85529,0.115,T,l,0.77,-0.62,1.817,,42.31,BOP,-1.45267,0.221079,0.00213852,0.123549 beta-lactamase_625_Y95E,beta-lactamase_625_95,TEM-1,beta-lactamase_625,P62593,0.123609,NO,95,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-1.715,-3.911,2.196,,0.122,,b,0.21,-0.37,3.355,,77.62,BHP,-2.16167,0.213352,0.00479449,0.123609 beta-lactamase_39_S233D,beta-lactamase_39_233,TEM-1,beta-lactamase_39,P62593,0.123624,NO,233,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.886,-3.5,1.614,,0.016,E,B,0.27,-1.01,5.361,,77.62,BPO,-1.17267,0.0495842,0.00311415,0.123624 beta-lactamase_625_L167W,beta-lactamase_625_167,TEM-1,beta-lactamase_625,P62593,0.123657,NO,167,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.138,-5.22,4.082,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.213352,0.00303566,0.123657 kka2_1:1_G245H,kka2_1:1_245,Kka2,kka2_1:1,P00552,0.123673,NO,245,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.812,-4.652,3.84,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.520039,0.00683899,0.123673 kka2_1:2_A224M,kka2_1:2_224,Kka2,kka2_1:2,P00552,0.123692,NO,224,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.977,-4.55,3.573,,,H,A,0.46,-1.26,1.646,,63.64,HHP,-1.41033,0.295029,0.00352047,0.123692 beta-lactamase_625_L248K,beta-lactamase_625_248,TEM-1,beta-lactamase_625,P62593,0.123709,NO,248,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.213352,0.00428493,0.123709 beta-lactamase_2500_V82P,beta-lactamase_2500_82,TEM-1,beta-lactamase_2500,P62593,0.123736,NO,82,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.325,-4.008,2.683,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.361275,0.00397046,0.123736 beta-lactamase_D177T,beta-lactamase_177,TEM-1,beta-lactamase,P62593,0.123751,NO,177,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.967,-3.465,2.498,5.08038,0.006,T,L,1.59,-1.02,3.536,,64.69,BAP,-0.873667,0.221079,0.000864022,0.123751 kka2_1:4_Y22K,kka2_1:4_22,Kka2,kka2_1:4,P00552,0.12376,NO,22,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-1.583,-3.742,2.159,,0.122,.,B,0.21,-0.8,1.838,,65.53,OHA,-1.80333,0.168804,0.00598977,0.12376 kka2_1:2_P76F,kka2_1:2_76,Kka2,kka2_1:2,P00552,0.123764,NO,76,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.449,-4.424,2.975,,0.331,.,B,0.52,-0.41,0.345,,63.64,HOO,-1.662,0.295029,0.00625685,0.123764 beta-lactamase_2500_A185Q,beta-lactamase_2500_185,TEM-1,beta-lactamase_2500,P62593,0.123813,NO,185,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.406,-4.108,2.702,,,H,A,0.46,-1.02,2.999,,65.03,HHP,-1.84033,0.361275,0.00467449,0.123813 PSD95pdz3_I327W,PSD95pdz3_327,PSD95pdz3,PSD95pdz3,P31016,0.123885,NO,327,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.63,-5.004,3.374,5.7413,,,,,14.0388,,,,PHH,-1.50167,0.0758425,0.000998774,0.123885 beta-lactamase_2500_N130E,beta-lactamase_2500_130,TEM-1,beta-lactamase_2500,P62593,0.12392,NO,130,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-0.798,-3.215,2.417,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.361275,0.000683376,0.12392 kka2_1:8_F203P,kka2_1:8_203,Kka2,kka2_1:8,P00552,0.123922,NO,203,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-0.911,-4.356,3.445,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.100394,0.00318738,0.123922 kka2_1:8_F203P,kka2_1:8_203,Kka2,kka2_1:8,P00552,0.123922,NO,203,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-0.911,-4.356,3.445,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.100394,0.00318738,0.123922 kka2_1:4_Q219D,kka2_1:4_219,Kka2,kka2_1:4,P00552,0.123941,NO,219,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-0.93,-3.333,2.403,,0.088,H,A,0.64,-0.85,1.537,,50,HPA,-1.05167,0.168804,0.00237913,0.123941 kka2_1:1_G95W,kka2_1:1_95,Kka2,kka2_1:1,P00552,0.123955,NO,95,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-2.403,-5.488,3.085,,0.126,E,B,0.29,-0.74,7.822,,71.59,HOA,-2.198,0.520039,0.00743616,0.123955 beta-lactamase_2500_A123R,beta-lactamase_2500_123,TEM-1,beta-lactamase_2500,P62593,0.123977,NO,123,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.834,-3.776,2.942,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.361275,0.0010157,0.123977 beta-lactamase_156_W227P,beta-lactamase_156_227,TEM-1,beta-lactamase_156,P62593,0.124024,NO,227,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-0.982,-4.323,3.341,,0.272,,B,0.47,-0.29,2.533,,74.48,OHH,-1.595,0.111618,0.00226019,0.124024 beta-lactamase_39_G43R,beta-lactamase_39_43,TEM-1,beta-lactamase_39,P62593,0.124036,NO,43,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.62,-3.933,3.313,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.0495842,0.00120151,0.124036 beta-lactamase_625_G249Y,beta-lactamase_625_249,TEM-1,beta-lactamase_625,P62593,0.12409,NO,249,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.213352,0.00220169,0.12409 kka2_1:2_G99I,kka2_1:2_99,Kka2,kka2_1:2,P00552,0.124092,NO,99,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.596,-4.264,3.668,,0.368,S,g,0.29,-0.87,,,,OOP,-1.63067,0.295029,0.00186055,0.124092 beta-lactamase_39_G76R,beta-lactamase_39_76,TEM-1,beta-lactamase_39,P62593,0.124101,NO,76,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.189,-3.905,2.716,,,H,A,0.29,-0.67,2.145,,67.83,OOH,-1.22267,0.0495842,0.00476637,0.124101 beta-lactamase_2500_R242E,beta-lactamase_2500_242,TEM-1,beta-lactamase_2500,P62593,0.124181,NO,242,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.361275,0.00452879,0.124181 beta-lactamase_625_Y262E,beta-lactamase_625_262,TEM-1,beta-lactamase_625,P62593,0.124183,NO,262,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.213352,0.00853516,0.124183 kka2_1:4_T187E,kka2_1:4_187,Kka2,kka2_1:4,P00552,0.1242,NO,187,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.273,-3.655,2.382,,0.007,E,B,0.22,-0.85,2.73,,52.27,HPB,-1.06567,0.168804,0.00693073,0.1242 beta-lactamase_625_A230H,beta-lactamase_625_230,TEM-1,beta-lactamase_625,P62593,0.12422,NO,230,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.154,-4.737,3.583,,0.01,E,B,0.46,-1.17,0.777,,50,HHA,-1.079,0.213352,0.00516841,0.12422 kka2_1:1_N200Y,kka2_1:1_200,Kka2,kka2_1:1,P00552,0.124261,NO,200,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-2.446,-4.44,1.994,,0.756,T,L,0.61,-0.08,17.299,17.299,64.39,APO,-2.08,0.520039,0.00838549,0.124261 kka2_1:4_V186Y,kka2_1:4_186,Kka2,kka2_1:4,P00552,0.124365,NO,186,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.011,-3.942,2.931,,,E,B,0.44,-0.61,0.679,,45.83,HHP,-1.10967,0.168804,0.00409703,0.124365 beta-lactamase_2500_I280W,beta-lactamase_2500_280,TEM-1,beta-lactamase_2500,P62593,0.124372,NO,280,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.361275,0.0530888,0.124372 kka2_1:8_L92Y,kka2_1:8_92,Kka2,kka2_1:8,P00552,0.124396,NO,92,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.893,-4.021,3.128,,0.007,E,B,1.59,-0.19,1.719,,63.26,HHH,-0.962,0.100394,0.00307177,0.124396 kka2_1:8_L92Y,kka2_1:8_92,Kka2,kka2_1:8,P00552,0.124396,NO,92,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.893,-4.021,3.128,,0.007,E,B,1.59,-0.19,1.719,,63.26,HHH,-0.962,0.100394,0.00307177,0.124396 beta-lactamase_39_G43P,beta-lactamase_39_43,TEM-1,beta-lactamase_39,P62593,0.124401,NO,43,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.62,-3.88,3.26,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.0495842,0.00120151,0.124401 beta-lactamase_2500_W227G,beta-lactamase_2500_227,TEM-1,beta-lactamase_2500,P62593,0.124403,NO,227,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-0.982,-2.451,1.469,,0.272,,B,0.47,-0.29,1.37,,74.48,OHH,-1.595,0.361275,0.00226019,0.124403 beta-lactamase_156_A133W,beta-lactamase_156_133,TEM-1,beta-lactamase_156,P62593,0.124433,NO,133,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.186,-5.303,4.117,,,H,A,0.46,-0.86,0.805,,67.83,HHP,-0.988333,0.111618,0.00468022,0.124433 kka2_1:2_F240M,kka2_1:2_240,Kka2,kka2_1:2,P00552,0.124465,NO,240,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-0.911,-4.239,3.328,,,H,A,0.58,-1.21,0.373,,50.38,BHH,-1.67267,0.295029,0.00552543,0.124465 beta-lactamase_2500_G240Q,beta-lactamase_2500_240,TEM-1,beta-lactamase_2500,P62593,0.124506,NO,240,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.361275,0.00591201,0.124506 beta-lactamase_2500_L137R,beta-lactamase_2500_137,TEM-1,beta-lactamase_2500,P62593,0.124652,NO,137,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.03,-4,2.97,,,H,A,0.55,-0.38,0.769,,42.31,HHP,-1.58933,0.361275,0.00278599,0.124652 kka2_1:4_R217T,kka2_1:4_217,Kka2,kka2_1:4,P00552,0.124689,NO,217,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.158,-3.559,2.401,,0.252,T,A,1.2,-0.59,2.074,,52.27,ABH,-1.127,0.168804,0.0047191,0.124689 kka2_1:2_T187L,kka2_1:2_187,Kka2,kka2_1:2,P00552,0.124693,NO,187,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.273,-3.26,1.987,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.295029,0.00693073,0.124693 kka2_1:1_G99N,kka2_1:1_99,Kka2,kka2_1:1,P00552,0.124793,NO,99,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.596,-3.476,2.88,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.520039,0.00186055,0.124793 beta-lactamase_2500_L79G,beta-lactamase_2500_79,TEM-1,beta-lactamase_2500,P62593,0.124805,NO,79,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.842,-3.806,2.964,,0.007,H,A,0.55,-0.16,0.823,,50.35,HHP,-1.44333,0.361275,0.000947397,0.124805 beta-lactamase_2500_D129W,beta-lactamase_2500_129,TEM-1,beta-lactamase_2500,P62593,0.124815,NO,129,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.816,-5.545,4.729,,,,B,0.75,-0.69,1.29,,34.97,PAP,-0.818,0.361275,0.00109178,0.124815 kka2_1:4_P76W,kka2_1:4_76,Kka2,kka2_1:4,P00552,0.124845,NO,76,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.449,-5.603,4.154,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.168804,0.00625685,0.124845 kka2_1:1_C209N,kka2_1:1_209,Kka2,kka2_1:1,P00552,0.124856,NO,209,C,N,CN,Special,Polar,5.07,5.47157,0.401575,139,121,132,11,108.5,114.1,5.6,-0.906,-4.174,3.268,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.520039,0.00260862,0.124856 beta-lactamase_156_K232M,beta-lactamase_156_232,TEM-1,beta-lactamase_156,P62593,0.124857,NO,232,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.012,-4.522,3.51,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.111618,0.00313441,0.124857 beta-lactamase_625_D33P,beta-lactamase_625_33,TEM-1,beta-lactamase_625,P62593,0.12486,NO,33,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.321,-3.968,1.647,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.213352,0.00435556,0.12486 kka2_1:8_D190S,kka2_1:8_190,Kka2,kka2_1:8,P00552,0.124868,NO,190,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.708,-3.189,2.481,,0.213,S,b,0.29,-0.82,,,,OAH,-0.711667,0.100394,0.00247989,0.124868 kka2_1:8_D190S,kka2_1:8_190,Kka2,kka2_1:8,P00552,0.124868,NO,190,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.708,-3.189,2.481,,0.213,S,b,0.29,-0.82,,,,OAH,-0.711667,0.100394,0.00247989,0.124868 kka2_1:8_L223Y,kka2_1:8_223,Kka2,kka2_1:8,P00552,0.124868,NO,223,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.861,-4.01,3.149,,,H,A,1.59,-1.24,1.017,,50,HHH,-0.854333,0.100394,0.00253574,0.124868 kka2_1:8_L223Y,kka2_1:8_223,Kka2,kka2_1:8,P00552,0.124868,NO,223,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.861,-4.01,3.149,,,H,A,1.59,-1.24,1.017,,50,HHH,-0.854333,0.100394,0.00253574,0.124868 beta-lactamase_2500_G236I,beta-lactamase_2500_236,TEM-1,beta-lactamase_2500,P62593,0.124886,NO,236,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.784,-4.139,3.355,,0.241,,b,0.29,-0.59,2.14,,64.69,HOO,-1.025,0.361275,0.00162372,0.124886 kka2_1:2_D82T,kka2_1:2_82,Kka2,kka2_1:2,P00552,0.124898,NO,82,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.946,-3.007,1.061,,0.341,E,b,0.75,0.52,11.923,11.923,63.64,HAH,-1.98,0.295029,0.00637516,0.124898 beta-lactamase_L247G,beta-lactamase_247,TEM-1,beta-lactamase,P62593,0.124921,NO,247,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.48,-3.763,2.283,5.28771,0.007,E,B,2.89,-0.72,2.951,,63.99,HHO,-1.79833,0.221079,0.00611275,0.124921 kka2_1:2_V113K,kka2_1:2_113,Kka2,kka2_1:2,P00552,0.124921,NO,113,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.233,-3.874,2.641,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.295029,0.00650191,0.124921 beta-lactamase_39_K71S,beta-lactamase_39_71,TEM-1,beta-lactamase_39,P62593,0.12493,NO,71,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-0.8,-3.161,2.361,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.0495842,0.00103192,0.12493 kka2_1:4_V153E,kka2_1:4_153,Kka2,kka2_1:4,P00552,0.124968,NO,153,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.092,-3.813,2.721,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.168804,0.00501119,0.124968 kka2_1:1_P76M,kka2_1:1_76,Kka2,kka2_1:1,P00552,0.1251,NO,76,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.449,-4.717,3.268,,0.331,.,B,0.52,-0.41,0.345,,63.64,HOO,-1.662,0.520039,0.00625685,0.1251 beta-lactamase_2500_G236F,beta-lactamase_2500_236,TEM-1,beta-lactamase_2500,P62593,0.125226,NO,236,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.784,-4.291,3.507,,0.241,,b,0.29,-0.59,2.14,,64.69,HOO,-1.025,0.361275,0.00162372,0.125226 beta-lactamase_2500_D177P,beta-lactamase_2500_177,TEM-1,beta-lactamase_2500,P62593,0.125228,NO,177,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.967,-3.764,2.797,,0.006,T,L,0.75,-1.02,4.131,,64.69,BAP,-0.873667,0.361275,0.000864022,0.125228 kka2_1:8_N200I,kka2_1:8_200,Kka2,kka2_1:8,P00552,0.12534,NO,200,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-2.446,-4.261,1.815,,0.756,T,L,0.43,-0.08,2.528,,64.39,APO,-2.08,0.100394,0.00838549,0.12534 kka2_1:8_N200I,kka2_1:8_200,Kka2,kka2_1:8,P00552,0.12534,NO,200,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-2.446,-4.261,1.815,,0.756,T,L,0.43,-0.08,2.528,,64.39,APO,-2.08,0.100394,0.00838549,0.12534 kka2_1:4_A34Y,kka2_1:4_34,Kka2,kka2_1:4,P00552,0.125596,NO,34,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.928,-4.223,3.295,,0.417,.,B,0.46,2.29,0.262,,52.27,AHH,-1.747,0.168804,0.00343484,0.125596 beta-lactamase_2500_L188R,beta-lactamase_2500_188,TEM-1,beta-lactamase_2500,P62593,0.125612,NO,188,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.166,-3.976,2.81,,,H,A,0.55,-0.3,17.865,17.865,60.14,PHB,-1.47033,0.361275,0.00295687,0.125612 beta-lactamase_2500_L284E,beta-lactamase_2500_284,TEM-1,beta-lactamase_2500,P62593,0.125656,NO,284,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.361275,0.0686156,0.125656 kka2_1:2_Y218R,kka2_1:2_218,Kka2,kka2_1:2,P00552,0.125702,NO,218,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-1.438,-3.984,2.546,,0.122,H,A,0.21,-0.69,1.022,,56.06,BHP,-1.17533,0.295029,0.0126098,0.125702 beta-lactamase_2500_F58P,beta-lactamase_2500_58,TEM-1,beta-lactamase_2500,P62593,0.125793,NO,58,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-2.914,-4.147,1.233,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.361275,0.00523369,0.125793 beta-lactamase_S233K,beta-lactamase_233,TEM-1,beta-lactamase,P62593,0.125821,NO,233,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.886,-3.496,1.61,4.98121,0.016,E,B,0.48,-1.01,5.361,,77.62,BPO,-1.17267,0.221079,0.00311415,0.125821 kka2_1:2_D101I,kka2_1:2_101,Kka2,kka2_1:2,P00552,0.125844,NO,101,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.028,-3.84,2.812,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.295029,0.00423361,0.125844 kka2_1:2_L241K,kka2_1:2_241,Kka2,kka2_1:2,P00552,0.125854,NO,241,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.158,-3.87,2.712,,0.08,H,A,0.55,-0.82,1.598,,63.26,HHH,-1.58533,0.295029,0.0117299,0.125854 kka2_1:2_R217M,kka2_1:2_217,Kka2,kka2_1:2,P00552,0.125873,NO,217,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.158,-4.484,3.326,,0.252,T,A,1.2,-0.59,0.381,,52.27,ABH,-1.127,0.295029,0.0047191,0.125873 beta-lactamase_625_D155V,beta-lactamase_625_155,TEM-1,beta-lactamase_625,P62593,0.125906,NO,155,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.889,-3.778,2.889,,0.049,,B,0.75,-0.9,4.922,,64.69,OAB,-1.62267,0.213352,0.00135315,0.125906 beta-lactamase_625_K71L,beta-lactamase_625_71,TEM-1,beta-lactamase_625,P62593,0.125907,NO,71,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-0.8,-3.358,2.558,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.213352,0.00103192,0.125907 beta-lactamase_2500_D155V,beta-lactamase_2500_155,TEM-1,beta-lactamase_2500,P62593,0.126164,NO,155,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.889,-3.778,2.889,,0.049,,B,0.75,-0.9,2.386,,64.69,OAB,-1.62267,0.361275,0.00135315,0.126164 kka2_1:4_L102H,kka2_1:4_102,Kka2,kka2_1:4,P00552,0.12618,NO,102,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.804,-4.931,4.127,,,T,A,0.55,-1.17,0.65,,42.42,AHH,-1.398,0.168804,0.00201332,0.12618 beta-lactamase_2500_S128Q,beta-lactamase_2500_128,TEM-1,beta-lactamase_2500,P62593,0.126212,NO,128,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-0.84,-3.674,2.834,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.361275,0.00071483,0.126212 Pab1_N127C,Pab1_127,Pab1,Pab1,P04147,0.126255,NO,127,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-1.079,-4.904,3.825,,0.138,E,B,1.05,-0.51,,,,OPH,-1.13633,0.175299,0.000805159,0.126255 beta-lactamase_625_I277Q,beta-lactamase_625_277,TEM-1,beta-lactamase_625,P62593,0.126277,NO,277,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.213352,0.0169305,0.126277 kka2_1:8_G213E,kka2_1:8_213,Kka2,kka2_1:8,P00552,0.126282,NO,213,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.596,-3.693,3.097,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.100394,0.00187654,0.126282 kka2_1:8_G213E,kka2_1:8_213,Kka2,kka2_1:8,P00552,0.126282,NO,213,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.596,-3.693,3.097,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.100394,0.00187654,0.126282 kka2_1:8_L39N,kka2_1:8_39,Kka2,kka2_1:8,P00552,0.126282,NO,39,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.223,-4.209,2.986,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.100394,0.00493618,0.126282 kka2_1:8_L39N,kka2_1:8_39,Kka2,kka2_1:8,P00552,0.126282,NO,39,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.223,-4.209,2.986,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.100394,0.00493618,0.126282 kka2_1:1_G205K,kka2_1:1_205,Kka2,kka2_1:1,P00552,0.126336,NO,205,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.596,-3.71,3.114,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.520039,0.00221855,0.126336 kka2_1:1_L19N,kka2_1:1_19,Kka2,kka2_1:1,P00552,0.126358,NO,19,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.254,-4.186,2.932,,0.08,T,A,0.55,-0.26,17.165,17.165,65.53,BHH,-2.221,0.520039,0.00620703,0.126358 beta-lactamase_2500_G240Y,beta-lactamase_2500_240,TEM-1,beta-lactamase_2500,P62593,0.126362,NO,240,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.361275,0.00591201,0.126362 kka2_1:1_V198H,kka2_1:1_198,Kka2,kka2_1:1,P00552,0.126441,NO,198,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.719,-4.876,3.157,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.520039,0.00835002,0.126441 kka2_1:2_G30I,kka2_1:2_30,Kka2,kka2_1:2,P00552,0.126479,NO,30,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.596,-4.264,3.668,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.295029,0.00159208,0.126479 kka2_1:1_R173V,kka2_1:1_173,Kka2,kka2_1:1,P00552,0.126573,NO,173,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.407,-3.707,1.3,,0.308,H,A,0.16,-0.13,14.756,14.756,65.53,HBH,-1.70533,0.520039,0.00784999,0.126573 beta-lactamase_I125E,beta-lactamase_125,TEM-1,beta-lactamase,P62593,0.12665,NO,125,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.441,-3.878,2.437,5.23481,,H,A,2.82,-0.7,2.301,,63.29,HHP,-1.248,0.221079,0.00383964,0.12665 beta-lactamase_625_I258D,beta-lactamase_625_258,TEM-1,beta-lactamase_625,P62593,0.12669,NO,258,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.213352,0.007931,0.12669 beta-lactamase_625_G243Y,beta-lactamase_625_243,TEM-1,beta-lactamase_625,P62593,0.126706,NO,243,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.213352,0.00464034,0.126706 beta-lactamase_S104L,beta-lactamase_104,TEM-1,beta-lactamase,P62593,0.126773,NO,104,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.015,-3.359,2.344,4.92365,0.04,,b,0.82,0.57,4.02,,63.29,HPO,-1.05267,0.221079,0.00218083,0.126773 beta-lactamase_2500_Y262Q,beta-lactamase_2500_262,TEM-1,beta-lactamase_2500,P62593,0.12678,NO,262,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.361275,0.00853516,0.12678 beta-lactamase_625_T27Y,beta-lactamase_625_27,TEM-1,beta-lactamase_625,P62593,0.126783,NO,27,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.905,-4.144,2.239,,0.007,H,A,0.22,-0.37,3.72,,93.01,APH,-1.97933,0.213352,0.00306559,0.126783 kka2_1:1_M197S,kka2_1:1_197,Kka2,kka2_1:1,P00552,0.126841,NO,197,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.707,-3.643,1.936,,0.121,E,B,1.59,-1.19,2.097,,65.53,HHH,-1.847,0.520039,0.00921295,0.126841 beta-lactamase_625_G234V,beta-lactamase_625_234,TEM-1,beta-lactamase_625,P62593,0.126892,NO,234,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.62,-3.754,3.134,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.213352,0.000889577,0.126892 beta-lactamase_625_D129S,beta-lactamase_625_129,TEM-1,beta-lactamase_625,P62593,0.126965,NO,129,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.816,-3.186,2.37,,,,B,0.75,-0.69,0.171,,34.97,PAP,-0.818,0.213352,0.00109178,0.126965 kka2_1:2_L260N,kka2_1:2_260,Kka2,kka2_1:2,P00552,0.126986,NO,260,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.741,-4.151,3.41,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.295029,0.0233782,0.126986 kka2_1:4_L260W,kka2_1:4_260,Kka2,kka2_1:4,P00552,0.127051,NO,260,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.741,-5.126,4.385,,0.022,H,A,0.55,-0.52,,,,HHA,-0.845667,0.168804,0.0233782,0.127051 kka2_1:4_G245Y,kka2_1:4_245,Kka2,kka2_1:4,P00552,0.127052,NO,245,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.812,-4.419,3.607,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.168804,0.00683899,0.127052 kka2_1:4_F133Q,kka2_1:4_133,Kka2,kka2_1:4,P00552,0.12708,NO,133,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-0.871,-4.345,3.474,,0.178,.,B,0.58,0.43,0.786,,42.42,OHA,-0.871667,0.168804,0.00182168,0.12708 beta-lactamase_39_T69R,beta-lactamase_39_69,TEM-1,beta-lactamase_39,P62593,0.127098,NO,69,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-0.973,-3.768,2.795,,,G,A,0.22,-1.24,4.194,,93.01,PPH,-1.01833,0.0495842,0.00127498,0.127098 kka2_1:4_I228K,kka2_1:4_228,Kka2,kka2_1:4,P00552,0.127137,NO,228,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.142,-3.919,2.777,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.168804,0.00458834,0.127137 beta-lactamase_2500_L205G,beta-lactamase_2500_205,TEM-1,beta-lactamase_2500,P62593,0.1272,NO,205,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.922,-3.783,2.861,,,H,A,0.55,-0.46,0.831,,42.31,PHH,-1.57767,0.361275,0.00255802,0.1272 beta-lactamase_2500_A133Q,beta-lactamase_2500_133,TEM-1,beta-lactamase_2500,P62593,0.127246,NO,133,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.186,-4.056,2.87,,,H,A,0.46,-0.86,2.649,,67.83,HHP,-0.988333,0.361275,0.00468022,0.127246 kka2_1:2_Y257R,kka2_1:2_257,Kka2,kka2_1:2,P00552,0.12727,NO,257,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-1.064,-4.088,3.024,,0.022,H,A,0.21,-0.88,0.833,,52.65,HHB,-1.39333,0.295029,0.0148191,0.12727 beta-lactamase_G76E,beta-lactamase_76,TEM-1,beta-lactamase,P62593,0.127292,NO,76,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.189,-3.614,2.425,4.73862,,H,A,2.05,-0.67,3.059,,67.83,OOH,-1.22267,0.221079,0.00476637,0.127292 kka2_1:2_A229P,kka2_1:2_229,Kka2,kka2_1:2,P00552,0.127362,NO,229,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.739,-3.997,2.258,,0.32,H,A,0.46,-0.7,6.549,,63.64,HHA,-1.851,0.295029,0.00942138,0.127362 beta-lactamase_625_K71S,beta-lactamase_625_71,TEM-1,beta-lactamase_625,P62593,0.127378,NO,71,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-0.8,-3.161,2.361,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.213352,0.00103192,0.127378 beta-lactamase_625_I125R,beta-lactamase_625_125,TEM-1,beta-lactamase_625,P62593,0.127475,NO,125,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.441,-4.126,2.685,,,H,A,0.48,-0.7,2.034,,63.29,HHP,-1.248,0.213352,0.00383964,0.127475 kka2_1:2_L223F,kka2_1:2_223,Kka2,kka2_1:2,P00552,0.127505,NO,223,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.861,-3.69,2.829,,,H,A,0.55,-1.24,0.266,,50,HHH,-0.854333,0.295029,0.00253574,0.127505 kka2_1:1_G213H,kka2_1:1_213,Kka2,kka2_1:1,P00552,0.127526,NO,213,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.596,-4.708,4.112,,,E,b,0.29,-0.4,,,,HOH,-0.920333,0.520039,0.00187654,0.127526 beta-lactamase_2500_L73E,beta-lactamase_2500_73,TEM-1,beta-lactamase_2500,P62593,0.127661,NO,73,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.507,-3.924,2.417,,,H,A,0.55,-0.64,2.178,,67.83,HHH,-1.487,0.361275,0.00488983,0.127661 beta-lactamase_39_S68G,beta-lactamase_39_68,TEM-1,beta-lactamase_39,P62593,0.127679,NO,68,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-0.913,-2.934,2.021,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.0495842,0.000800065,0.127679 beta-lactamase_D155T,beta-lactamase_155,TEM-1,beta-lactamase,P62593,0.127709,NO,155,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.889,-3.445,2.556,4.92265,0.049,,B,0.45,-0.9,3.208,,64.69,OAB,-1.62267,0.221079,0.00135315,0.127709 beta-lactamase_625_I229E,beta-lactamase_625_229,TEM-1,beta-lactamase_625,P62593,0.127715,NO,229,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.267,-3.864,2.597,,0.083,E,B,0.48,-0.76,1.69,,50,HHH,-1.58767,0.213352,0.00477249,0.127715 kka2_1:2_M197E,kka2_1:2_197,Kka2,kka2_1:2,P00552,0.127717,NO,197,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.707,-3.927,2.22,,0.121,E,B,0.55,-1.19,2.097,,65.53,HHH,-1.847,0.295029,0.00921295,0.127717 beta-lactamase_2500_I45K,beta-lactamase_2500_45,TEM-1,beta-lactamase_2500,P62593,0.127724,NO,45,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-2.421,-3.76,1.339,,,E,B,0.48,-0.3,3.793,,77.62,HHA,-2.30267,0.361275,0.00452842,0.127724 beta-lactamase_625_A133L,beta-lactamase_625_133,TEM-1,beta-lactamase_625,P62593,0.127785,NO,133,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.186,-3.396,2.21,,,H,A,0.46,-0.86,0.373,,67.83,HHP,-0.988333,0.213352,0.00468022,0.127785 beta-lactamase_2500_W227T,beta-lactamase_2500_227,TEM-1,beta-lactamase_2500,P62593,0.12779,NO,227,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-0.982,-3.696,2.714,,0.272,,B,0.47,-0.29,1.37,,74.48,OHH,-1.595,0.361275,0.00226019,0.12779 beta-lactamase_2500_N134E,beta-lactamase_2500_134,TEM-1,beta-lactamase_2500,P62593,0.127849,NO,134,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-0.879,-3.212,2.333,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.361275,0.000644786,0.127849 beta-lactamase_2500_I258E,beta-lactamase_2500_258,TEM-1,beta-lactamase_2500,P62593,0.127916,NO,258,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.361275,0.007931,0.127916 kka2_1:8_W236I,kka2_1:8_236,Kka2,kka2_1:8,P00552,0.127924,NO,236,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-1.363,-3.761,2.398,,0.303,H,A,1.51,-0.76,1.87,,48.48,AHH,-1.81267,0.100394,0.0088796,0.127924 kka2_1:8_W236I,kka2_1:8_236,Kka2,kka2_1:8,P00552,0.127924,NO,236,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-1.363,-3.761,2.398,,0.303,H,A,1.51,-0.76,1.87,,48.48,AHH,-1.81267,0.100394,0.0088796,0.127924 beta-lactamase_2500_T178Y,beta-lactamase_2500_178,TEM-1,beta-lactamase_2500,P62593,0.12796,NO,178,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-0.791,-4.162,3.371,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.361275,0.000684366,0.12796 kka2_1:4_G205D,kka2_1:4_205,Kka2,kka2_1:4,P00552,0.127994,NO,205,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.596,-3.497,2.901,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.168804,0.00221855,0.127994 kka2_1:4_D261R,kka2_1:4_261,Kka2,kka2_1:4,P00552,0.127997,NO,261,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.708,-3.961,3.253,,0.146,G,A,0.75,-0.33,,,,HAA,-0.759333,0.168804,0.0224846,0.127997 beta-lactamase_625_S233D,beta-lactamase_625_233,TEM-1,beta-lactamase_625,P62593,0.128079,NO,233,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.886,-3.5,1.614,,0.016,E,B,0.27,-1.01,1.773,,77.62,BPO,-1.17267,0.213352,0.00311415,0.128079 beta-lactamase_156_E46P,beta-lactamase_156_46,TEM-1,beta-lactamase_156,P62593,0.128167,NO,46,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.94,-4.039,2.099,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.111618,0.00427568,0.128167 beta-lactamase_2500_S68K,beta-lactamase_2500_68,TEM-1,beta-lactamase_2500,P62593,0.12824,NO,68,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-0.913,-3.258,2.345,,0.064,G,A,0.27,-1.03,2.824,,64.69,HPP,-1.37233,0.361275,0.000800065,0.12824 kka2_1:2_S104K,kka2_1:2_104,Kka2,kka2_1:2,P00552,0.12825,NO,104,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.436,-3.48,2.044,,0.536,T,A,0.27,-1.11,5.49,,63.64,HPP,-1.91433,0.295029,0.00555207,0.12825 kka2_1:1_G201H,kka2_1:1_201,Kka2,kka2_1:1,P00552,0.128291,NO,201,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.56,-3.46,1.9,,0.149,T,l,0.29,-0.57,16.092,16.092,52.65,POB,-1.92233,0.520039,0.00820117,0.128291 kka2_1:1_G233W,kka2_1:1_233,Kka2,kka2_1:1,P00552,0.128428,NO,233,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.748,-5.239,4.491,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.520039,0.00232366,0.128428 beta-lactamase_156_A133E,beta-lactamase_156_133,TEM-1,beta-lactamase_156,P62593,0.128508,NO,133,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.186,-3.597,2.411,,,H,A,0.46,-0.86,0.805,,67.83,HHP,-0.988333,0.111618,0.00468022,0.128508 kka2_1:1_I228D,kka2_1:1_228,Kka2,kka2_1:1,P00552,0.12853,NO,228,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.142,-4.061,2.919,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.520039,0.00458834,0.12853 beta-lactamase_156_L205P,beta-lactamase_156_205,TEM-1,beta-lactamase_156,P62593,0.128618,NO,205,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.922,-4.159,3.237,,,H,A,0.55,-0.46,0.678,,42.31,PHH,-1.57767,0.111618,0.00255802,0.128618 beta-lactamase_2500_D83P,beta-lactamase_2500_83,TEM-1,beta-lactamase_2500,P62593,0.128624,NO,83,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.066,-3.748,2.682,,0.354,H,A,0.75,0.22,0.239,,48.95,HAH,-1.34733,0.361275,0.00205968,0.128624 beta-lactamase_625_D177Q,beta-lactamase_625_177,TEM-1,beta-lactamase_625,P62593,0.128652,NO,177,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.967,-3.799,2.832,,0.006,T,L,0.75,-1.02,1.333,,64.69,BAP,-0.873667,0.213352,0.000864022,0.128652 kka2_1:1_G21Q,kka2_1:1_21,Kka2,kka2_1:1,P00552,0.128778,NO,21,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.368,-2.867,1.499,,0.586,T,l,0.29,-0.75,10.291,10.291,71.59,HOH,-2.10167,0.520039,0.00709648,0.128778 beta-lactamase_2500_L73K,beta-lactamase_2500_73,TEM-1,beta-lactamase_2500,P62593,0.128779,NO,73,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.507,-3.846,2.339,,,H,A,0.55,-0.64,2.178,,67.83,HHH,-1.487,0.361275,0.00488983,0.128779 beta-lactamase_G234L,beta-lactamase_234,TEM-1,beta-lactamase,P62593,0.128795,NO,234,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.62,-3.808,3.188,4.24221,0.023,E,B,0.46,-0.86,,,,POH,-1.25733,0.221079,0.000889577,0.128795 beta-lactamase_39_S68A,beta-lactamase_39_68,TEM-1,beta-lactamase_39,P62593,0.128856,NO,68,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-0.913,-2.711,1.798,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.0495842,0.000800065,0.128856 kka2_1:1_T187R,kka2_1:1_187,Kka2,kka2_1:1,P00552,0.128872,NO,187,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.273,-3.94,2.667,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.520039,0.00693073,0.128872 beta-lactamase_39_L120R,beta-lactamase_39_120,TEM-1,beta-lactamase_39,P62593,0.128896,NO,120,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.044,-2.871,1.827,,,H,A,0.55,-1.13,22.254,22.254,64.69,AHO,-1.13633,0.0495842,0.00143563,0.128896 beta-lactamase_0_A123D,beta-lactamase_0_123,TEM-1,beta-lactamase_0,P62593,0.128963,NO,123,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.834,-3.743,2.909,,0.039,H,A,0.46,-0.72,1.308,,41.26,PHH,-1.47367,0.0500837,0.0010157,0.128963 Ubiquitin_A46K,Ubiquitin_46,Uba1,Ubiquitin,P0CG48,0.129032,NO,46,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.77,-3.597,1.827,5.38761,0.398,T,L,2.34,-0.8,6.506,,51.09,HHO,-1.505,0.205827,0.000581142,0.129032 Ubiquitin_I44E,Ubiquitin_44,Uba1,Ubiquitin,P0CG48,0.129032,NO,44,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.566,-3.711,2.145,4.71256,,E,B,0.27,-1.17,5.26,,39.71,HHH,-1.38567,0.205827,0.000613305,0.129032 Ubiquitin_K48H,Ubiquitin_48,Uba1,Ubiquitin,P0CG48,0.129032,NO,48,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.436,-2.986,1.55,5.03072,0.132,E,B,2.92,-0.28,1.539,,53.87,OBP,-1.6,0.205827,0.000394633,0.129032 Ubiquitin_L73T,Ubiquitin_73,Uba1,Ubiquitin,P0CG48,0.129032,NO,73,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.801,-2.837,1.036,5.27116,0.518,,B,0.77,1,10.519,10.519,34.31,BHB,-1.858,0.205827,0.000710624,0.129032 beta-lactamase_39_M209D,beta-lactamase_39_209,TEM-1,beta-lactamase_39,P62593,0.129111,NO,209,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.442,-4.067,2.625,,,H,A,0.55,-0.97,1.167,,64.69,HHA,-1.52633,0.0495842,0.00625021,0.129111 beta-lactamase_2500_N134G,beta-lactamase_2500_134,TEM-1,beta-lactamase_2500,P62593,0.12915,NO,134,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-0.879,-2.976,2.097,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.361275,0.000644786,0.12915 beta-lactamase_2500_N274Y,beta-lactamase_2500_274,TEM-1,beta-lactamase_2500,P62593,0.129166,NO,274,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.361275,0.0110418,0.129166 kka2_1:1_E182Y,kka2_1:1_182,Kka2,kka2_1:1,P00552,0.129167,NO,182,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.516,-3.156,1.64,,0.326,,B,1.52,0.75,14.547,14.547,65.53,OAA,-1.806,0.520039,0.00641548,0.129167 beta-lactamase_M1S,beta-lactamase_1,TEM-1,beta-lactamase,P62593,0.129171,NO,1,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.998,-3.067,1.069,,,,,,,,,,OHP,-1.97,0.221079,0.00162771,0.129171 kka2_1:1_Q219C,kka2_1:1_219,Kka2,kka2_1:1,P00552,0.129196,NO,219,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-0.93,-5.139,4.209,,0.088,H,A,0.4,-0.85,1.917,,50,HPA,-1.05167,0.520039,0.00237913,0.129196 beta-lactamase_156_D155K,beta-lactamase_156_155,TEM-1,beta-lactamase_156,P62593,0.129203,NO,155,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.889,-3.426,2.537,,0.049,,B,0.75,-0.9,0.315,,64.69,OAB,-1.62267,0.111618,0.00135315,0.129203 beta-lactamase_156_L74W,beta-lactamase_156_74,TEM-1,beta-lactamase_156,P62593,0.129261,NO,74,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.296,-5.261,3.965,,,H,A,0.55,-0.91,0.746,,50,HHO,-1.34933,0.111618,0.00493255,0.129261 beta-lactamase_2500_D155G,beta-lactamase_2500_155,TEM-1,beta-lactamase_2500,P62593,0.129265,NO,155,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.889,-3.177,2.288,,0.049,,B,0.75,-0.9,2.386,,64.69,OAB,-1.62267,0.361275,0.00135315,0.129265 beta-lactamase_2500_M67R,beta-lactamase_2500_67,TEM-1,beta-lactamase_2500,P62593,0.129272,NO,67,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-2.231,-3.989,1.758,,0.006,G,P,0.55,-0.81,2.653,,65.03,HHP,-1.502,0.361275,0.00409753,0.129272 beta-lactamase_625_I258E,beta-lactamase_625_258,TEM-1,beta-lactamase_625,P62593,0.129334,NO,258,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.213352,0.007931,0.129334 kka2_1:2_F256N,kka2_1:2_256,Kka2,kka2_1:2,P00552,0.129387,NO,256,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.49,-4.16,2.67,,,H,A,0.58,-0.78,1.653,,53.03,HHH,-1.423,0.295029,0.0132841,0.129387 kka2_1:2_M116E,kka2_1:2_116,Kka2,kka2_1:2,P00552,0.129387,NO,116,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-2.482,-3.963,1.481,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.295029,0.00745147,0.129387 kka2_1:1_G74L,kka2_1:1_74,Kka2,kka2_1:1,P00552,0.129439,NO,74,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.18,-3.872,2.692,,0.621,T,l,0.75,0.2,15.356,15.356,64.39,POH,-1.91667,0.520039,0.00587035,0.129439 beta-lactamase_156_L191R,beta-lactamase_156_191,TEM-1,beta-lactamase_156,P62593,0.129476,NO,191,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.087,-4.02,2.933,,,H,A,0.55,0.09,1.372,,63.29,BHH,-1.445,0.111618,0.00263549,0.129476 beta-lactamase_156_V260Y,beta-lactamase_156_260,TEM-1,beta-lactamase_156,P62593,0.129482,NO,260,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.101,-3.316,2.215,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.111618,0.00471757,0.129482 kka2_1:2_N200I,kka2_1:2_200,Kka2,kka2_1:2,P00552,0.129485,NO,200,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-2.446,-4.261,1.815,,0.756,T,L,0.61,-0.08,2.836,,64.39,APO,-2.08,0.295029,0.00838549,0.129485 kka2_1:1_L232I,kka2_1:1_232,Kka2,kka2_1:1,P00552,0.129511,NO,232,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.514,-2.661,1.147,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.520039,0.00800103,0.129511 beta-lactamase_156_K232L,beta-lactamase_156_232,TEM-1,beta-lactamase_156,P62593,0.129516,NO,232,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.012,-3.401,2.389,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.111618,0.00313441,0.129516 kka2_1:4_G30E,kka2_1:4_30,Kka2,kka2_1:4,P00552,0.129582,NO,30,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.596,-3.693,3.097,,0.54,S,g,0.29,3.76,,,,HOO,-1.51133,0.168804,0.00159208,0.129582 kka2_1:1_V113P,kka2_1:1_113,Kka2,kka2_1:1,P00552,0.129588,NO,113,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.233,-4.102,2.869,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.520039,0.00650191,0.129588 beta-lactamase_2500_C121Y,beta-lactamase_2500_121,TEM-1,beta-lactamase_2500,P62593,0.129589,NO,121,C,Y,CY,Special,Hydrophobic,5.07,5.66,0.59,194,121,181,60,108.5,193.6,85.1,-0.953,-4.188,3.235,,,H,A,0.46,-0.81,1.174,,63.29,HOP,-1.46767,0.361275,0.000744322,0.129589 beta-lactamase_39_V259K,beta-lactamase_39_259,TEM-1,beta-lactamase_39,P62593,0.129626,NO,259,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.0495842,0.0070773,0.129626 beta-lactamase_2500_E35K,beta-lactamase_2500_35,TEM-1,beta-lactamase_2500,P62593,0.129685,NO,35,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-0.869,-3.075,2.206,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.361275,0.00174441,0.129685 beta-lactamase_2500_P181Q,beta-lactamase_2500_181,TEM-1,beta-lactamase_2500,P62593,0.129709,NO,181,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.813,-3.925,3.112,,,H,A,0.52,-1.14,1.946,,61.54,HOH,-1.795,0.361275,0.000703122,0.129709 kka2_1:1_L67F,kka2_1:1_67,Kka2,kka2_1:1,P00552,0.129751,NO,67,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.741,-3.645,2.904,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.520039,0.00102787,0.129751 beta-lactamase_L136E,beta-lactamase_136,TEM-1,beta-lactamase,P62593,0.129842,NO,136,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.232,-3.938,2.706,5.31114,,H,A,2.89,-0.34,1.539,,48.95,HHH,-1.088,0.221079,0.00442304,0.129842 beta-lactamase_625_G240M,beta-lactamase_625_240,TEM-1,beta-lactamase_625,P62593,0.129881,NO,240,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.213352,0.00591201,0.129881 kka2_1:2_G210W,kka2_1:2_210,Kka2,kka2_1:2,P00552,0.129928,NO,210,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.095,-5.322,4.227,,0.103,T,A,0.29,-0.62,0.271,,50,OOB,-0.966667,0.295029,0.00598378,0.129928 beta-lactamase_G142W,beta-lactamase_142,TEM-1,beta-lactamase,P62593,0.129945,NO,142,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.707,-5.146,4.439,4.55474,0.034,,p,0.77,-0.64,1.947,,64.69,OOO,-0.834,0.221079,0.00060149,0.129945 beta-lactamase_M67W,beta-lactamase_67,TEM-1,beta-lactamase,P62593,0.129945,NO,67,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-2.231,-5.379,3.148,4.9618,0.006,G,P,1.07,-0.81,1.463,,65.03,HHP,-1.502,0.221079,0.00409753,0.129945 kka2_1:4_F203I,kka2_1:4_203,Kka2,kka2_1:4,P00552,0.129985,NO,203,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-0.911,-3.319,2.408,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.168804,0.00318738,0.129985 beta-lactamase_2500_A132C,beta-lactamase_2500_132,TEM-1,beta-lactamase_2500,P62593,0.129999,NO,132,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.9,-4.503,3.603,,,H,A,0.46,-0.93,8.408,,64.69,PHH,-1.138,0.361275,0.000962524,0.129999 beta-lactamase_156_T179R,beta-lactamase_156_179,TEM-1,beta-lactamase_156,P62593,0.130016,NO,179,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.085,-3.749,2.664,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.111618,0.00226045,0.130016 beta-lactamase_2500_M209K,beta-lactamase_2500_209,TEM-1,beta-lactamase_2500,P62593,0.130022,NO,209,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.442,-3.673,2.231,,,H,A,0.55,-0.97,3.229,,64.69,HHA,-1.52633,0.361275,0.00625021,0.130022 kka2_1:1_L184F,kka2_1:1_184,Kka2,kka2_1:1,P00552,0.130063,NO,184,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.496,-2.947,1.451,,0.489,E,B,0.55,-0.06,19.127,19.127,63.26,AHH,-1.24833,0.520039,0.00518742,0.130063 kka2_1:2_I254E,kka2_1:2_254,Kka2,kka2_1:2,P00552,0.130079,NO,254,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.933,-3.931,1.998,,0.135,H,A,1.52,-0.6,2.562,,71.59,BHH,-1.668,0.295029,0.0132375,0.130079 beta-lactamase_625_L100D,beta-lactamase_625_100,TEM-1,beta-lactamase_625,P62593,0.130097,NO,100,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.218,-4.132,2.914,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.213352,0.00413885,0.130097 kka2_1:1_G233H,kka2_1:1_233,Kka2,kka2_1:1,P00552,0.13016,NO,233,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.748,-4.708,3.96,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.520039,0.00232366,0.13016 kka2_1:1_D190F,kka2_1:1_190,Kka2,kka2_1:1,P00552,0.130185,NO,190,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.708,-4.32,3.612,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.520039,0.00247989,0.130185 beta-lactamase_2500_I277D,beta-lactamase_2500_277,TEM-1,beta-lactamase_2500,P62593,0.130191,NO,277,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.361275,0.0169305,0.130191 beta-lactamase_39_G234K,beta-lactamase_39_234,TEM-1,beta-lactamase_39,P62593,0.130247,NO,234,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.62,-3.682,3.062,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.0495842,0.000889577,0.130247 beta-lactamase_2500_I277R,beta-lactamase_2500_277,TEM-1,beta-lactamase_2500,P62593,0.130268,NO,277,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.361275,0.0169305,0.130268 beta-lactamase_156_G236P,beta-lactamase_156_236,TEM-1,beta-lactamase_156,P62593,0.130301,NO,236,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.784,-3.879,3.095,,0.241,,b,0.29,-0.59,1.883,,64.69,HOO,-1.025,0.111618,0.00162372,0.130301 beta-lactamase_39_Y262P,beta-lactamase_39_262,TEM-1,beta-lactamase_39,P62593,0.130303,NO,262,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.0495842,0.00853516,0.130303 beta-lactamase_156_I277Q,beta-lactamase_156_277,TEM-1,beta-lactamase_156,P62593,0.130383,NO,277,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.111618,0.0169305,0.130383 beta-lactamase_M1D,beta-lactamase_1,TEM-1,beta-lactamase,P62593,0.130424,NO,1,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.998,-3.6,1.602,,,,,,,,,,OHP,-1.97,0.221079,0.00162771,0.130424 kka2_1:1_D220I,kka2_1:1_220,Kka2,kka2_1:1,P00552,0.130469,NO,220,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.787,-3.808,3.021,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.520039,0.00158066,0.130469 beta-lactamase_625_G43M,beta-lactamase_625_43,TEM-1,beta-lactamase_625,P62593,0.130539,NO,43,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.62,-4.93,4.31,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.213352,0.00120151,0.130539 Pab1_H172P,Pab1_172,Pab1,Pab1,P04147,0.130561,NO,172,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-1.21,-3.697,2.487,,0.076,E,B,0.35,-0.87,,,,HBH,-1.26667,0.175299,0.000296642,0.130561 beta-lactamase_156_V78R,beta-lactamase_156_78,TEM-1,beta-lactamase_156,P62593,0.130668,NO,78,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.459,-4.181,2.722,,,H,A,0.44,-0.47,1.132,,63.64,HHH,-1.17833,0.111618,0.00492501,0.130668 beta-lactamase_2500_G43H,beta-lactamase_2500_43,TEM-1,beta-lactamase_2500,P62593,0.130685,NO,43,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.62,-4.68,4.06,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.361275,0.00120151,0.130685 beta-lactamase_2500_E164Q,beta-lactamase_2500_164,TEM-1,beta-lactamase_2500,P62593,0.13069,NO,164,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-0.948,-3.358,2.41,,0.011,T,B,1.04,-0.4,0.352,,64.69,HAO,-1.388,0.361275,0.00137286,0.13069 beta-lactamase_I259G,beta-lactamase_259,TEM-1,beta-lactamase,P62593,0.130726,NO,259,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.522,-3.678,2.156,5.28457,,E,B,1,-0.8,1.24,,64.34,HHH,-1.53267,0.221079,0.0070773,0.130726 kka2_1:1_Q136P,kka2_1:1_136,Kka2,kka2_1:1,P00552,0.13073,NO,136,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-3.021,-2.734,-0.287,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.520039,0.00624149,0.13073 kka2_1:1_R258M,kka2_1:1_258,Kka2,kka2_1:1,P00552,0.130802,NO,258,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.626,-3.325,1.699,,0.316,H,A,1.2,-0.85,7.485,7.485,53.03,HBH,-1.25933,0.520039,0.00983174,0.130802 kka2_1:1_V214W,kka2_1:1_214,Kka2,kka2_1:1,P00552,0.130809,NO,214,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.261,-5.433,4.172,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.520039,0.00692782,0.130809 E1_Ubiquitin_G76W,E1_Ubiquitin_76,Uba1,E1_Ubiquitin,P0CG63,0.130858,NO,76,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.999,-2.364,1.365,,0.23,,B,0.75,0.08,1.702,,83.73,OOO,-0.999,0.18783,0.00125575,0.130858 kka2_1:2_I196H,kka2_1:2_196,Kka2,kka2_1:2,P00552,0.130922,NO,196,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-2.115,-4.791,2.676,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.295029,0.0107273,0.130922 beta-lactamase_I256Q,beta-lactamase_256,TEM-1,beta-lactamase,P62593,0.13105,NO,256,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.621,-4.318,2.697,5.3196,,E,B,1,-0.84,1.615,,73.08,BHH,-1.80667,0.221079,0.00710634,0.13105 beta-lactamase_2500_L74Y,beta-lactamase_2500_74,TEM-1,beta-lactamase_2500,P62593,0.131258,NO,74,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.296,-4.105,2.809,,,H,A,0.55,-0.91,0.746,,50,HHO,-1.34933,0.361275,0.00493255,0.131258 kka2_1:4_L223Y,kka2_1:4_223,Kka2,kka2_1:4,P00552,0.131293,NO,223,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.861,-4.01,3.149,,,H,A,1.59,-1.24,1.268,,50,HHH,-0.854333,0.168804,0.00253574,0.131293 beta-lactamase_625_A185D,beta-lactamase_625_185,TEM-1,beta-lactamase_625,P62593,0.131464,NO,185,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.406,-3.867,2.461,,,H,A,0.46,-1.02,0.365,,65.03,HHP,-1.84033,0.213352,0.00467449,0.131464 beta-lactamase_2500_G243W,beta-lactamase_2500_243,TEM-1,beta-lactamase_2500,P62593,0.131481,NO,243,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.361275,0.00464034,0.131481 beta-lactamase_2500_G43N,beta-lactamase_2500_43,TEM-1,beta-lactamase_2500,P62593,0.131532,NO,43,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.62,-3.448,2.828,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.361275,0.00120151,0.131532 beta-lactamase_625_D48P,beta-lactamase_625_48,TEM-1,beta-lactamase_625,P62593,0.131534,NO,48,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.101,-3.766,2.665,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.213352,0.0027273,0.131534 beta-lactamase_I206P,beta-lactamase_206,TEM-1,beta-lactamase,P62593,0.131587,NO,206,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-2.429,-4.04,1.611,5.3727,0.173,H,A,1,-0.34,2.061,,77.62,HHA,-1.805,0.221079,0.00528934,0.131587 kka2_1:1_V75E,kka2_1:1_75,Kka2,kka2_1:1,P00552,0.131693,NO,75,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-2.06,-3.835,1.775,,0.042,.,B,0.44,-0.2,2.815,,71.59,OHO,-1.563,0.520039,0.00693733,0.131693 kka2_1:2_L223H,kka2_1:2_223,Kka2,kka2_1:2,P00552,0.131695,NO,223,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.861,-4.978,4.117,,,H,A,0.55,-1.24,0.266,,50,HHH,-0.854333,0.295029,0.00253574,0.131695 beta-lactamase_I244Q,beta-lactamase_244,TEM-1,beta-lactamase,P62593,0.13173,NO,244,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.555,-4.255,2.7,5.35885,,E,B,0.01,-0.84,0.379,,77.62,HHH,-1.385,0.221079,0.00605379,0.13173 beta-lactamase_2500_D155A,beta-lactamase_2500_155,TEM-1,beta-lactamase_2500,P62593,0.131821,NO,155,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.889,-3.327,2.438,,0.049,,B,0.75,-0.9,2.386,,64.69,OAB,-1.62267,0.361275,0.00135315,0.131821 beta-lactamase_G279R,beta-lactamase_279,TEM-1,beta-lactamase,P62593,0.131861,NO,279,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.038,-3.907,2.869,4.53882,,H,A,0.46,-0.97,3.066,,62.59,HOH,-1.36467,0.221079,0.0192826,0.131861 kka2_1:4_L193H,kka2_1:4_193,Kka2,kka2_1:4,P00552,0.131863,NO,193,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.983,-4.891,3.908,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.168804,0.00480179,0.131863 kka2_1:1_E59I,kka2_1:1_59,Kka2,kka2_1:1,P00552,0.131864,NO,59,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-0.952,-4.057,3.105,,0.187,.,L,1.04,0.62,2.648,,50.38,PAH,-1.53,0.520039,0.00280355,0.131864 kka2_1:4_L223W,kka2_1:4_223,Kka2,kka2_1:4,P00552,0.131886,NO,223,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.861,-5.208,4.347,,,H,A,1.59,-1.24,1.268,,50,HHH,-0.854333,0.168804,0.00253574,0.131886 beta-lactamase_2500_C121H,beta-lactamase_2500_121,TEM-1,beta-lactamase_2500,P62593,0.131889,NO,121,C,H,CH,Special,PositiveCharge,5.07,7.59,2.52,174,121,155,34,108.5,153.2,44.7,-0.953,-4.827,3.874,,,H,A,0.46,-0.81,1.174,,63.29,HOP,-1.46767,0.361275,0.000744322,0.131889 beta-lactamase_39_P181W,beta-lactamase_39_181,TEM-1,beta-lactamase_39,P62593,0.131918,NO,181,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.813,-5.545,4.732,,,H,A,0.52,-1.14,1.946,,61.54,HOH,-1.795,0.0495842,0.000703122,0.131918 beta-lactamase_156_V42D,beta-lactamase_156_42,TEM-1,beta-lactamase_156,P62593,0.131988,NO,42,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.564,-4.059,2.495,,0.017,E,B,0.44,-0.51,2.576,,63.99,BHO,-1.042,0.111618,0.00404515,0.131988 kka2_1:4_L170Q,kka2_1:4_170,Kka2,kka2_1:4,P00552,0.132004,NO,170,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.28,-4.219,2.939,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.168804,0.00730791,0.132004 beta-lactamase_2500_E164T,beta-lactamase_2500_164,TEM-1,beta-lactamase_2500,P62593,0.132035,NO,164,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-0.948,-3.491,2.543,,0.011,T,B,1.04,-0.4,0.352,,64.69,HAO,-1.388,0.361275,0.00137286,0.132035 beta-lactamase_G248T,beta-lactamase_248,TEM-1,beta-lactamase,P62593,0.132082,NO,248,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.794,-2.612,0.818,4.69798,,E,b,0.23,-0.43,1.782,,61.19,HOO,-1.52867,0.221079,0.00428493,0.132082 kka2_1:8_I228E,kka2_1:8_228,Kka2,kka2_1:8,P00552,0.13211,NO,228,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.142,-3.95,2.808,,,H,A,1.52,-1.2,1.521,,71.59,AHH,-1.54633,0.100394,0.00458834,0.13211 kka2_1:8_I228E,kka2_1:8_228,Kka2,kka2_1:8,P00552,0.13211,NO,228,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.142,-3.95,2.808,,,H,A,1.52,-1.2,1.521,,71.59,AHH,-1.54633,0.100394,0.00458834,0.13211 beta-lactamase_625_A185Q,beta-lactamase_625_185,TEM-1,beta-lactamase_625,P62593,0.132226,NO,185,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.406,-4.108,2.702,,,H,A,0.46,-1.02,0.365,,65.03,HHP,-1.84033,0.213352,0.00467449,0.132226 kka2_1:1_A191K,kka2_1:1_191,Kka2,kka2_1:1,P00552,0.132226,NO,191,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.831,-3.519,2.688,,,.,b,0.46,-0.94,0.53,,50,AHO,-0.868667,0.520039,0.00338807,0.132226 beta-lactamase_625_L136E,beta-lactamase_625_136,TEM-1,beta-lactamase_625,P62593,0.132337,NO,136,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.232,-3.938,2.706,,,H,A,0.55,-0.34,0.336,,48.95,HHH,-1.088,0.213352,0.00442304,0.132337 beta-lactamase_2500_A246D,beta-lactamase_2500_246,TEM-1,beta-lactamase_2500,P62593,0.132402,NO,246,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.121,-4.086,1.965,,0.01,E,B,0.46,-1.01,0.753,,73.78,HHH,-1.55633,0.361275,0.00569458,0.132402 beta-lactamase_625_L188E,beta-lactamase_625_188,TEM-1,beta-lactamase_625,P62593,0.132415,NO,188,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.166,-2.834,1.668,,,H,A,0.55,-0.3,2.982,,60.14,PHB,-1.47033,0.213352,0.00295687,0.132415 kka2_1:2_A222F,kka2_1:2_222,Kka2,kka2_1:2,P00552,0.132429,NO,222,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.725,-4.095,3.37,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.295029,0.00207657,0.132429 kka2_1:1_T73C,kka2_1:1_73,Kka2,kka2_1:1,P00552,0.132434,NO,73,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.51,-3.584,1.074,,0.309,H,A,0.22,0.35,4.126,,56.06,PPO,-2.02333,0.520039,0.00628605,0.132434 Pab1_I128K,Pab1_128,Pab1,Pab1,P04147,0.132492,NO,128,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.345,-3.72,2.375,,0.008,E,B,1.68,-0.6,1.706,,78.68,PHH,-1.231,0.175299,0.00104192,0.132492 beta-lactamase_625_N134I,beta-lactamase_625_134,TEM-1,beta-lactamase_625,P62593,0.132578,NO,134,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-0.879,-4.036,3.157,,0.138,H,A,0.61,-0.6,3.776,,53.15,HPH,-1.02233,0.213352,0.000644786,0.132578 kka2_1:2_G99N,kka2_1:2_99,Kka2,kka2_1:2,P00552,0.132647,NO,99,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.596,-3.476,2.88,,0.368,S,g,0.29,-0.87,,,,OOP,-1.63067,0.295029,0.00186055,0.132647 kka2_1:1_A78H,kka2_1:1_78,Kka2,kka2_1:1,P00552,0.132771,NO,78,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.744,-4.753,3.009,,0.078,.,B,0.46,-0.53,0.206,,56.06,OHH,-1.863,0.520039,0.00457299,0.132771 kka2_1:1_F171I,kka2_1:1_171,Kka2,kka2_1:1,P00552,0.132771,NO,171,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.326,-2.784,1.458,,0.154,H,A,1.62,-0.1,13.679,13.679,63.64,HHH,-1.45433,0.520039,0.00821426,0.132771 kka2_1:4_L241E,kka2_1:4_241,Kka2,kka2_1:4,P00552,0.132793,NO,241,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.158,-4.005,2.847,,0.08,H,A,0.55,-0.82,1.598,,63.26,HHH,-1.58533,0.168804,0.0117299,0.132793 beta-lactamase_39_Y44K,beta-lactamase_39_44,TEM-1,beta-lactamase_39,P62593,0.132937,NO,44,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-2.547,-3.823,1.276,,,E,B,0.21,-0.45,2.683,,73.78,OHH,-1.86267,0.0495842,0.00426364,0.132937 kka2_1:2_I221W,kka2_1:2_221,Kka2,kka2_1:2,P00552,0.132968,NO,221,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.739,-3.219,1.48,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.295029,0.00945908,0.132968 kka2_1:8_L232K,kka2_1:8_232,Kka2,kka2_1:8,P00552,0.133032,NO,232,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.514,-3.945,2.431,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.100394,0.00800103,0.133032 kka2_1:8_L232K,kka2_1:8_232,Kka2,kka2_1:8,P00552,0.133032,NO,232,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.514,-3.945,2.431,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.100394,0.00800103,0.133032 beta-lactamase_2500_F228P,beta-lactamase_2500_228,TEM-1,beta-lactamase_2500,P62593,0.13305,NO,228,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-2.342,-3.088,0.746,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.361275,0.0046669,0.13305 beta-lactamase_I125G,beta-lactamase_125,TEM-1,beta-lactamase,P62593,0.133051,NO,125,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.441,-3.768,2.327,5.23481,,H,A,2.82,-0.7,2.301,,63.29,HHP,-1.248,0.221079,0.00383964,0.133051 kka2_1:2_G95P,kka2_1:2_95,Kka2,kka2_1:2,P00552,0.133052,NO,95,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-2.403,-3.948,1.545,,0.126,E,B,0.29,-0.74,0.359,,71.59,HOA,-2.198,0.295029,0.00743616,0.133052 beta-lactamase_156_F64R,beta-lactamase_156_64,TEM-1,beta-lactamase_156,P62593,0.133096,NO,64,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-0.841,-4.158,3.317,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.111618,0.000947691,0.133096 kka2_1:1_N200C,kka2_1:1_200,Kka2,kka2_1:1,P00552,0.133193,NO,200,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-2.446,-5.276,2.83,,0.756,T,L,0.61,-0.08,17.299,17.299,64.39,APO,-2.08,0.520039,0.00838549,0.133193 beta-lactamase_2500_A185M,beta-lactamase_2500_185,TEM-1,beta-lactamase_2500,P62593,0.133293,NO,185,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.406,-4.39,2.984,,,H,A,0.46,-1.02,2.999,,65.03,HHP,-1.84033,0.361275,0.00467449,0.133293 kka2_1:1_A117W,kka2_1:1_117,Kka2,kka2_1:1,P00552,0.133335,NO,117,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.828,-5.385,4.557,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.520039,0.00282984,0.133335 kka2_1:1_V75N,kka2_1:1_75,Kka2,kka2_1:1,P00552,0.133344,NO,75,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-2.06,-4.176,2.116,,0.042,.,B,0.44,-0.2,2.815,,71.59,OHO,-1.563,0.520039,0.00693733,0.133344 kka2_1:2_G88I,kka2_1:2_88,Kka2,kka2_1:2,P00552,0.133395,NO,88,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.689,-4.119,2.43,,0.54,S,l,0.75,1.51,2.814,,65.53,HOB,-1.718,0.295029,0.00685559,0.133395 kka2_1:1_D220Q,kka2_1:1_220,Kka2,kka2_1:1,P00552,0.13341,NO,220,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.787,-3.763,2.976,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.520039,0.00158066,0.13341 kka2_1:4_V113G,kka2_1:4_113,Kka2,kka2_1:4,P00552,0.133563,NO,113,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.233,-3.759,2.526,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.168804,0.00650191,0.133563 beta-lactamase_2500_S68M,beta-lactamase_2500_68,TEM-1,beta-lactamase_2500,P62593,0.133564,NO,68,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-0.913,-4.529,3.616,,0.064,G,A,0.27,-1.03,2.824,,64.69,HPP,-1.37233,0.361275,0.000800065,0.133564 kka2_1:1_I141M,kka2_1:1_141,Kka2,kka2_1:1,P00552,0.13357,NO,141,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.495,-2.864,1.369,,0.068,H,A,0.48,-0.01,7.546,7.546,92.05,BHA,-1.689,0.520039,0.00744745,0.13357 kka2_1:2_L260S,kka2_1:2_260,Kka2,kka2_1:2,P00552,0.133769,NO,260,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.741,-3.639,2.898,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.295029,0.0233782,0.133769 kka2_1:1_T187I,kka2_1:1_187,Kka2,kka2_1:1,P00552,0.133773,NO,187,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.273,-2.925,1.652,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.520039,0.00693073,0.133773 beta-lactamase_2500_G43W,beta-lactamase_2500_43,TEM-1,beta-lactamase_2500,P62593,0.133795,NO,43,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.62,-5.097,4.477,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.361275,0.00120151,0.133795 beta-lactamase_625_M209N,beta-lactamase_625_209,TEM-1,beta-lactamase_625,P62593,0.13381,NO,209,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.442,-4.092,2.65,,,H,A,0.55,-0.97,1.167,,64.69,HHA,-1.52633,0.213352,0.00625021,0.13381 beta-lactamase_625_C75Q,beta-lactamase_625_75,TEM-1,beta-lactamase_625,P62593,0.133812,NO,75,C,Q,CQ,Special,Polar,5.07,6.24429,1.17429,154,121,146,25,108.5,143.8,35.3,-1.245,-4.228,2.983,,,H,A,0.46,-0.87,2.141,,50,HOO,-1.24333,0.213352,0.0034616,0.133812 kka2_1:2_I228K,kka2_1:2_228,Kka2,kka2_1:2,P00552,0.133818,NO,228,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.142,-3.919,2.777,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.295029,0.00458834,0.133818 beta-lactamase_2500_N130M,beta-lactamase_2500_130,TEM-1,beta-lactamase_2500,P62593,0.133869,NO,130,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-0.798,-4.705,3.907,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.361275,0.000683376,0.133869 beta-lactamase_2500_L120N,beta-lactamase_2500_120,TEM-1,beta-lactamase_2500,P62593,0.133896,NO,120,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.044,-4.027,2.983,,,H,A,0.55,-1.13,2.48,,64.69,AHO,-1.13633,0.361275,0.00143563,0.133896 beta-lactamase_2500_A124F,beta-lactamase_2500_124,TEM-1,beta-lactamase_2500,P62593,0.133916,NO,124,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.181,-4.133,2.952,,,H,A,0.46,-0.9,0.314,,64.34,HHH,-1.152,0.361275,0.00481399,0.133916 kka2_1:4_F264E,kka2_1:4_264,Kka2,kka2_1:4,P00552,0.133978,NO,264,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.02,-3.943,2.923,,0.296,,?,1.62,0.02,1.93,,71.59,HHO,-0.9655,0.168804,,0.133978 kka2_1:2_I196Y,kka2_1:2_196,Kka2,kka2_1:2,P00552,0.134028,NO,196,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-2.115,-2.902,0.787,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.295029,0.0107273,0.134028 beta-lactamase_T158Y,beta-lactamase_158,TEM-1,beta-lactamase,P62593,0.134126,NO,158,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.116,-4.258,3.142,5.32011,0.036,,B,0.98,-0.85,2.755,,69.58,HPB,-1.269,0.221079,0.00341825,0.134126 kka2_1:2_A117F,kka2_1:2_117,Kka2,kka2_1:2,P00552,0.134248,NO,117,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.828,-4.094,3.266,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.295029,0.00282984,0.134248 kka2_1:1_V185Q,kka2_1:1_185,Kka2,kka2_1:1,P00552,0.134337,NO,185,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.045,-4.205,3.16,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.520039,0.00367031,0.134337 beta-lactamase_2500_M209Y,beta-lactamase_2500_209,TEM-1,beta-lactamase_2500,P62593,0.13434,NO,209,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.442,-3.865,2.423,,,H,A,0.55,-0.97,3.229,,64.69,HHA,-1.52633,0.361275,0.00625021,0.13434 beta-lactamase_G242E,beta-lactamase_242,TEM-1,beta-lactamase,P62593,0.134392,NO,242,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.319,-3.504,2.185,4.68003,,E,B,0.87,-1.05,1.079,,50,BOH,-1.428,0.221079,0.00452879,0.134392 E1_Ubiquitin_H70E,E1_Ubiquitin_70,Uba1,E1_Ubiquitin,P0CG63,0.134394,NO,70,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-1.36,,,,0.05,E,B,0.61,-0.97,,,93.18,HBH,-1.146,0.18783,0.00206914,0.134394 beta-lactamase_625_G281K,beta-lactamase_625_281,TEM-1,beta-lactamase_625,P62593,0.134453,NO,281,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.213352,0.0406482,0.134453 beta-lactamase_625_K71C,beta-lactamase_625_71,TEM-1,beta-lactamase_625,P62593,0.134458,NO,71,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-0.8,-5.087,4.287,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.213352,0.00103192,0.134458 beta-lactamase_625_S233R,beta-lactamase_625_233,TEM-1,beta-lactamase_625,P62593,0.134544,NO,233,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.886,-3.819,1.933,,0.016,E,B,0.27,-1.01,1.773,,77.62,BPO,-1.17267,0.213352,0.00311415,0.134544 kka2_1:1_T51Y,kka2_1:1_51,Kka2,kka2_1:1,P00552,0.134601,NO,51,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.199,-4.283,2.084,,0.05,E,B,0.22,-0.05,3.056,,63.64,BPA,-1.76767,0.520039,0.00628861,0.134601 Pab1_K131D,Pab1_131,Pab1,Pab1,P04147,0.134608,NO,131,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.083,-3.286,2.203,,0.462,E,B,1.82,0.57,,,,HBP,-1.12467,0.175299,0.000349395,0.134608 beta-lactamase_39_G234H,beta-lactamase_39_234,TEM-1,beta-lactamase_39,P62593,0.13461,NO,234,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.62,-4.68,4.06,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.0495842,0.000889577,0.13461 beta-lactamase_39_L74Y,beta-lactamase_39_74,TEM-1,beta-lactamase_39,P62593,0.134644,NO,74,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.296,-4.105,2.809,,,H,A,0.55,-0.91,1.581,,50,HHO,-1.34933,0.0495842,0.00493255,0.134644 beta-lactamase_2500_A235H,beta-lactamase_2500_235,TEM-1,beta-lactamase_2500,P62593,0.134659,NO,235,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.266,-4.769,3.503,,0.32,E,B,0.46,-0.86,0.891,,50,OHO,-0.89,0.361275,0.00493474,0.134659 beta-lactamase_625_G234D,beta-lactamase_625_234,TEM-1,beta-lactamase_625,P62593,0.134667,NO,234,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.62,-3.469,2.849,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.213352,0.000889577,0.134667 kka2_1:1_D250K,kka2_1:1_250,Kka2,kka2_1:1,P00552,0.134693,NO,250,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.015,-3.438,2.423,,0.274,.,b,0.75,-0.46,4.177,,51.89,OAP,-1.83933,0.520039,0.0177103,0.134693 beta-lactamase_2500_V72R,beta-lactamase_2500_72,TEM-1,beta-lactamase_2500,P62593,0.134714,NO,72,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.658,-4.097,2.439,,,H,A,0.44,-1.03,2.079,,65.73,BHH,-1.32167,0.361275,0.00501194,0.134714 kka2_1:4_F263I,kka2_1:4_263,Kka2,kka2_1:4,P00552,0.134729,NO,263,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-0.911,-3.319,2.408,,0.006,G,A,0.58,-0.12,2.284,,45.83,AHH,-0.92,0.168804,0.0172454,0.134729 kka2_1:2_D261F,kka2_1:2_261,Kka2,kka2_1:2,P00552,0.134732,NO,261,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.708,-4.32,3.612,,0.146,G,A,0.75,-0.33,,,,HAA,-0.759333,0.295029,0.0224846,0.134732 beta-lactamase_156_A230K,beta-lactamase_156_230,TEM-1,beta-lactamase_156,P62593,0.134804,NO,230,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.154,-3.583,2.429,,0.01,E,B,0.46,-1.17,2.179,,50,HHA,-1.079,0.111618,0.00516841,0.134804 kka2_1:1_L241F,kka2_1:1_241,Kka2,kka2_1:1,P00552,0.134858,NO,241,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.158,-1.703,0.545,,0.08,H,A,0.55,-0.82,1.685,,63.26,HHH,-1.58533,0.520039,0.0117299,0.134858 beta-lactamase_156_F64D,beta-lactamase_156_64,TEM-1,beta-lactamase_156,P62593,0.135106,NO,64,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-0.841,-3.919,3.078,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.111618,0.000947691,0.135106 beta-lactamase_39_D161P,beta-lactamase_39_161,TEM-1,beta-lactamase_39,P62593,0.135108,NO,161,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.891,-3.704,2.813,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.0495842,0.000897697,0.135108 kka2_1:4_H188G,kka2_1:4_188,Kka2,kka2_1:4,P00552,0.135298,NO,188,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-0.913,-3.41,2.497,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.168804,0.00273139,0.135298 kka2_1:1_D227K,kka2_1:1_227,Kka2,kka2_1:1,P00552,0.135307,NO,227,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.758,-3.364,1.606,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.520039,0.00745029,0.135307 beta-lactamase_2500_G43V,beta-lactamase_2500_43,TEM-1,beta-lactamase_2500,P62593,0.13531,NO,43,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.62,-3.754,3.134,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.361275,0.00120151,0.13531 beta-lactamase_G234F,beta-lactamase_234,TEM-1,beta-lactamase,P62593,0.135311,NO,234,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.62,-4.292,3.672,4.24221,0.023,E,B,0.46,-0.86,,,,POH,-1.25733,0.221079,0.000889577,0.135311 beta-lactamase_M66W,beta-lactamase_66,TEM-1,beta-lactamase,P62593,0.135311,NO,66,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.362,-5.087,3.725,5.29561,0.013,,A,1.3,-0.7,1.319,,73.08,OHH,-1.49567,0.221079,0.00412876,0.135311 kka2_1:1_A34M,kka2_1:1_34,Kka2,kka2_1:1,P00552,0.135331,NO,34,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.928,-4.54,3.612,,0.417,.,B,0.46,2.29,0.262,,52.27,AHH,-1.747,0.520039,0.00343484,0.135331 kka2_1:1_M197P,kka2_1:1_197,Kka2,kka2_1:1,P00552,0.135339,NO,197,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.707,-4.141,2.434,,0.121,E,B,1.59,-1.19,2.097,,65.53,HHH,-1.847,0.520039,0.00921295,0.135339 PSD95pdz3_I327E,PSD95pdz3_327,PSD95pdz3,PSD95pdz3,P31016,0.135352,NO,327,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.63,-3.572,1.942,5.7413,,,,,14.0388,,,,PHH,-1.50167,0.0758425,0.000998774,0.135352 beta-lactamase_625_L74H,beta-lactamase_625_74,TEM-1,beta-lactamase_625,P62593,0.135375,NO,74,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.296,-4.896,3.6,,,H,A,0.55,-0.91,0.895,,50,HHO,-1.34933,0.213352,0.00493255,0.135375 beta-lactamase_Y95D,beta-lactamase_95,TEM-1,beta-lactamase,P62593,0.135395,NO,95,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-1.715,-4.078,2.363,5.67068,0.122,,b,0.96,-0.37,2.341,,77.62,BHP,-2.16167,0.221079,0.00479449,0.135395 beta-lactamase_2500_M209E,beta-lactamase_2500_209,TEM-1,beta-lactamase_2500,P62593,0.135399,NO,209,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.442,-3.84,2.398,,,H,A,0.55,-0.97,3.229,,64.69,HHA,-1.52633,0.361275,0.00625021,0.135399 beta-lactamase_2500_E87K,beta-lactamase_2500_87,TEM-1,beta-lactamase_2500,P62593,0.135419,NO,87,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.421,-2.715,1.294,,0.048,,B,1.04,0.92,17.923,17.923,64.69,PAP,-1.969,0.361275,0.00337888,0.135419 beta-lactamase_156_S128W,beta-lactamase_156_128,TEM-1,beta-lactamase_156,P62593,0.135428,NO,128,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-0.84,-5.322,4.482,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.111618,0.00071483,0.135428 kka2_1:2_V185F,kka2_1:2_185,Kka2,kka2_1:2,P00552,0.135525,NO,185,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.045,-3.962,2.917,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.295029,0.00367031,0.135525 kka2_1:1_A229D,kka2_1:1_229,Kka2,kka2_1:1,P00552,0.135545,NO,229,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.739,-3.667,1.928,,0.32,H,A,0.46,-0.7,6.549,,63.64,HHA,-1.851,0.520039,0.00942138,0.135545 beta-lactamase_625_N134M,beta-lactamase_625_134,TEM-1,beta-lactamase_625,P62593,0.135566,NO,134,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-0.879,-4.702,3.823,,0.138,H,A,0.61,-0.6,3.776,,53.15,HPH,-1.02233,0.213352,0.000644786,0.135566 beta-lactamase_39_A124K,beta-lactamase_39_124,TEM-1,beta-lactamase_39,P62593,0.135614,NO,124,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.181,-3.561,2.38,,,H,A,0.46,-0.9,1.367,,64.34,HHH,-1.152,0.0495842,0.00481399,0.135614 kka2_1:2_D62K,kka2_1:2_62,Kka2,kka2_1:2,P00552,0.135669,NO,62,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.591,-3.652,2.061,,0.262,H,A,0.75,0.08,10.048,10.048,64.39,PAA,-1.77833,0.295029,0.00744243,0.135669 beta-lactamase_2500_D129Q,beta-lactamase_2500_129,TEM-1,beta-lactamase_2500,P62593,0.135681,NO,129,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.816,-3.637,2.821,,,,B,0.75,-0.69,1.29,,34.97,PAP,-0.818,0.361275,0.00109178,0.135681 beta-lactamase_D177W,beta-lactamase_177,TEM-1,beta-lactamase,P62593,0.135694,NO,177,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.967,-5.545,4.578,5.08038,0.006,T,L,1.59,-1.02,3.536,,64.69,BAP,-0.873667,0.221079,0.000864022,0.135694 beta-lactamase_625_W227L,beta-lactamase_625_227,TEM-1,beta-lactamase_625,P62593,0.135882,NO,227,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-0.982,-3.387,2.405,,0.272,,B,0.47,-0.29,2.533,,74.48,OHH,-1.595,0.213352,0.00226019,0.135882 beta-lactamase_625_I245W,beta-lactamase_625_245,TEM-1,beta-lactamase_625,P62593,0.135887,NO,245,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.213352,0.00391032,0.135887 beta-lactamase_G236K,beta-lactamase_236,TEM-1,beta-lactamase,P62593,0.136084,NO,236,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.784,-3.651,2.867,4.7915,0.241,,b,0.23,-0.59,1.883,,64.69,HOA,-1.36933,0.221079,0.00162372,0.136084 kka2_1:1_C77M,kka2_1:1_77,Kka2,kka2_1:1,P00552,0.136097,NO,77,C,M,CM,Special,Hydrophobic,5.07,5.74,0.67,196,121,149,28,108.5,162.9,54.4,-1.477,-4.643,3.166,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.520039,0.00441216,0.136097 beta-lactamase_625_G249I,beta-lactamase_625_249,TEM-1,beta-lactamase_625,P62593,0.136115,NO,249,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.213352,0.00220169,0.136115 E1_Ubiquitin_G76S,E1_Ubiquitin_76,Uba1,E1_Ubiquitin,P0CG63,0.136163,NO,76,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.999,-3.159,2.16,,0.23,,B,0.75,0.08,1.702,,83.73,OOO,-0.999,0.18783,0.00125575,0.136163 kka2_1:2_L260W,kka2_1:2_260,Kka2,kka2_1:2,P00552,0.136184,NO,260,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.741,-5.126,4.385,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.295029,0.0233782,0.136184 kka2_1:8_L19S,kka2_1:8_19,Kka2,kka2_1:8,P00552,0.136242,NO,19,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.254,-3.764,2.51,,0.08,T,A,1.59,-0.26,2.044,,65.53,BHH,-2.221,0.100394,0.00620703,0.136242 kka2_1:8_L19S,kka2_1:8_19,Kka2,kka2_1:8,P00552,0.136242,NO,19,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.254,-3.764,2.51,,0.08,T,A,1.59,-0.26,2.044,,65.53,BHH,-2.221,0.100394,0.00620703,0.136242 beta-lactamase_625_N130E,beta-lactamase_625_130,TEM-1,beta-lactamase_625,P62593,0.136265,NO,130,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-0.798,-3.215,2.417,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.213352,0.000683376,0.136265 beta-lactamase_156_F58P,beta-lactamase_156_58,TEM-1,beta-lactamase_156,P62593,0.13632,NO,58,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-2.914,-4.147,1.233,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.111618,0.00523369,0.13632 beta-lactamase_2500_L191P,beta-lactamase_2500_191,TEM-1,beta-lactamase_2500,P62593,0.136326,NO,191,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.087,-4.09,3.003,,,H,A,0.55,0.09,1.703,,63.29,BHH,-1.445,0.361275,0.00263549,0.136326 beta-lactamase_2500_C121N,beta-lactamase_2500_121,TEM-1,beta-lactamase_2500,P62593,0.136358,NO,121,C,N,CN,Special,Polar,5.07,5.47157,0.401575,139,121,132,11,108.5,114.1,5.6,-0.953,-4.045,3.092,,,H,A,0.46,-0.81,1.174,,63.29,HOP,-1.46767,0.361275,0.000744322,0.136358 beta-lactamase_156_D177P,beta-lactamase_156_177,TEM-1,beta-lactamase_156,P62593,0.136462,NO,177,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.967,-3.764,2.797,,0.006,T,L,0.75,-1.02,2.072,,64.69,BAP,-0.873667,0.111618,0.000864022,0.136462 beta-lactamase_625_L136P,beta-lactamase_625_136,TEM-1,beta-lactamase_625,P62593,0.136469,NO,136,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.232,-4.152,2.92,,,H,A,0.55,-0.34,0.336,,48.95,HHH,-1.088,0.213352,0.00442304,0.136469 beta-lactamase_156_A132L,beta-lactamase_156_132,TEM-1,beta-lactamase_156,P62593,0.136488,NO,132,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.9,-3.146,2.246,,,H,A,0.46,-0.93,10.621,,64.69,PHH,-1.138,0.111618,0.000962524,0.136488 kka2_1:1_T187Q,kka2_1:1_187,Kka2,kka2_1:1,P00552,0.136615,NO,187,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.273,-4.098,2.825,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.520039,0.00693073,0.136615 kka2_1:2_L39N,kka2_1:2_39,Kka2,kka2_1:2,P00552,0.136621,NO,39,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.223,-4.209,2.986,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.295029,0.00493618,0.136621 kka2_1:1_D220M,kka2_1:1_220,Kka2,kka2_1:1,P00552,0.136686,NO,220,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.787,-4.844,4.057,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.520039,0.00158066,0.136686 kka2_1:2_R226W,kka2_1:2_226,Kka2,kka2_1:2,P00552,0.136768,NO,226,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.392,-2.291,0.899,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.295029,0.0108032,0.136768 beta-lactamase_2500_L135D,beta-lactamase_2500_135,TEM-1,beta-lactamase_2500,P62593,0.136776,NO,135,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.002,-4.125,3.123,,0.117,H,A,0.55,-0.58,0.795,,43.71,PHH,-1.03767,0.361275,0.00244423,0.136776 beta-lactamase_625_M184R,beta-lactamase_625_184,TEM-1,beta-lactamase_625,P62593,0.136824,NO,184,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.593,-3.928,2.335,,,H,A,0.55,-0.87,2.765,,62.94,HHH,-1.41,0.213352,0.00356019,0.136824 kka2_1:1_P76F,kka2_1:1_76,Kka2,kka2_1:1,P00552,0.136846,NO,76,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.449,-4.424,2.975,,0.331,.,B,0.52,-0.41,0.345,,63.64,HOO,-1.662,0.520039,0.00625685,0.136846 beta-lactamase_2500_K71F,beta-lactamase_2500_71,TEM-1,beta-lactamase_2500,P62593,0.136864,NO,71,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-0.8,-4.292,3.492,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.361275,0.00103192,0.136864 beta-lactamase_I275S,beta-lactamase_275,TEM-1,beta-lactamase,P62593,0.136953,NO,275,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.397,-3.695,2.298,5.3999,0.015,H,A,1,-0.52,0.836,,62.59,PHH,-1.541,0.221079,0.0141984,0.136953 beta-lactamase_2500_P65R,beta-lactamase_2500_65,TEM-1,beta-lactamase_2500,P62593,0.137043,NO,65,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.894,-3.951,3.057,,0.098,E,B,0.52,-0.62,0.3,,40.56,HOH,-1.03233,0.361275,0.00152776,0.137043 beta-lactamase_156_T179Y,beta-lactamase_156_179,TEM-1,beta-lactamase_156,P62593,0.137062,NO,179,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.085,-4.097,3.012,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.111618,0.00226045,0.137062 kka2_1:4_E262Y,kka2_1:4_262,Kka2,kka2_1:4,P00552,0.137067,NO,262,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-0.829,-4.189,3.36,,0.059,G,A,1.04,-0.18,2.383,,42.42,AAH,-0.816,0.168804,0.0191586,0.137067 beta-lactamase_V72E,beta-lactamase_72,TEM-1,beta-lactamase,P62593,0.137088,NO,72,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.658,-3.755,2.097,5.80324,,H,A,2.78,-1.03,2.964,,65.73,BHH,-1.32167,0.221079,0.00501194,0.137088 kka2_1:1_P76K,kka2_1:1_76,Kka2,kka2_1:1,P00552,0.137116,NO,76,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.449,-3.635,2.186,,0.331,.,B,0.52,-0.41,0.345,,63.64,HOO,-1.662,0.520039,0.00625685,0.137116 kka2_1:8_G189E,kka2_1:8_189,Kka2,kka2_1:8,P00552,0.137153,NO,189,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.596,-3.693,3.097,,0.034,S,l,0.75,-0.99,,,,BOA,-0.739,0.100394,0.00253688,0.137153 kka2_1:8_G189E,kka2_1:8_189,Kka2,kka2_1:8,P00552,0.137153,NO,189,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.596,-3.693,3.097,,0.034,S,l,0.75,-0.99,,,,BOA,-0.739,0.100394,0.00253688,0.137153 beta-lactamase_R91P,beta-lactamase_91,TEM-1,beta-lactamase,P62593,0.137156,NO,91,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.392,-3.876,2.484,5.92536,0.444,,B,0.68,0.96,1.318,,50.35,OBB,-1.73367,0.221079,0.00380226,0.137156 kka2_1:2_D216H,kka2_1:2_216,Kka2,kka2_1:2,P00552,0.137178,NO,216,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.785,-2.903,2.118,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.295029,0.00229969,0.137178 beta-lactamase_L191K,beta-lactamase_191,TEM-1,beta-lactamase,P62593,0.137248,NO,191,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.087,-3.741,2.654,5.72226,,H,A,1.07,0.09,1.23,,63.29,BHH,-1.445,0.221079,0.00263549,0.137248 kka2_1:4_G189Q,kka2_1:4_189,Kka2,kka2_1:4,P00552,0.137254,NO,189,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.596,-4.153,3.557,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.168804,0.00253688,0.137254 kka2_1:1_M197Y,kka2_1:1_197,Kka2,kka2_1:1,P00552,0.137318,NO,197,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.707,-4.145,2.438,,0.121,E,B,1.59,-1.19,2.097,,65.53,HHH,-1.847,0.520039,0.00921295,0.137318 beta-lactamase_625_L74R,beta-lactamase_625_74,TEM-1,beta-lactamase_625,P62593,0.137344,NO,74,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.296,-3.939,2.643,,,H,A,0.55,-0.91,0.895,,50,HHO,-1.34933,0.213352,0.00493255,0.137344 kka2_1:2_F256I,kka2_1:2_256,Kka2,kka2_1:2,P00552,0.137361,NO,256,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.49,-3.685,2.195,,,H,A,0.58,-0.78,1.653,,53.03,HHH,-1.423,0.295029,0.0132841,0.137361 beta-lactamase_2500_D129H,beta-lactamase_2500_129,TEM-1,beta-lactamase_2500,P62593,0.137376,NO,129,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.816,-4.453,3.637,,,,B,0.75,-0.69,1.29,,34.97,PAP,-0.818,0.361275,0.00109178,0.137376 kka2_1:8_A78D,kka2_1:8_78,Kka2,kka2_1:8,P00552,0.137381,NO,78,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.744,-3.601,1.857,,0.078,,B,1.04,-0.53,1.251,,56.06,OHH,-1.863,0.100394,0.00457299,0.137381 kka2_1:8_A78D,kka2_1:8_78,Kka2,kka2_1:8,P00552,0.137381,NO,78,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.744,-3.601,1.857,,0.078,,B,1.04,-0.53,1.251,,56.06,OHH,-1.863,0.100394,0.00457299,0.137381 beta-lactamase_2500_M209F,beta-lactamase_2500_209,TEM-1,beta-lactamase_2500,P62593,0.137415,NO,209,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.442,-2.51,1.068,,,H,A,0.55,-0.97,3.229,,64.69,HHA,-1.52633,0.361275,0.00625021,0.137415 kka2_1:4_V186D,kka2_1:4_186,Kka2,kka2_1:4,P00552,0.137434,NO,186,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.011,-4.046,3.035,,,E,B,0.44,-0.61,0.679,,45.83,HHP,-1.10967,0.168804,0.00409703,0.137434 kka2_1:1_A255C,kka2_1:1_255,Kka2,kka2_1:1,P00552,0.137463,NO,255,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.715,-5.069,3.354,,0.466,H,A,0.46,-0.52,0.946,,65.53,HHH,-1.71267,0.520039,0.0126809,0.137463 beta-lactamase_625_G243V,beta-lactamase_625_243,TEM-1,beta-lactamase_625,P62593,0.137553,NO,243,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.213352,0.00464034,0.137553 kka2_1:4_M120S,kka2_1:4_120,Kka2,kka2_1:4,P00552,0.137569,NO,120,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-3.877,-3.662,-0.215,,,H,A,0.55,-0.42,2.259,,92.05,HHB,-2.16733,0.168804,0.00265808,0.137569 beta-lactamase_2500_N134S,beta-lactamase_2500_134,TEM-1,beta-lactamase_2500,P62593,0.137576,NO,134,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-0.879,-2.985,2.106,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.361275,0.000644786,0.137576 kka2_1:8_W15N,kka2_1:8_15,Kka2,kka2_1:8,P00552,0.137608,NO,15,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-1.392,-4.342,2.95,,0.01,G,A,1.51,0.15,0.827,,52.27,HHH,-2.10533,0.100394,0.00585505,0.137608 kka2_1:8_W15N,kka2_1:8_15,Kka2,kka2_1:8,P00552,0.137608,NO,15,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-1.392,-4.342,2.95,,0.01,G,A,1.51,0.15,0.827,,52.27,HHH,-2.10533,0.100394,0.00585505,0.137608 kka2_1:1_L241I,kka2_1:1_241,Kka2,kka2_1:1,P00552,0.137611,NO,241,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.158,-3.164,2.006,,0.08,H,A,0.55,-0.82,1.685,,63.26,HHH,-1.58533,0.520039,0.0117299,0.137611 kka2_1:2_C77I,kka2_1:2_77,Kka2,kka2_1:2,P00552,0.13763,NO,77,C,I,CI,Special,Hydrophobic,5.07,6.02,0.95,198,121,131,10,108.5,166.7,58.2,-1.477,-3.673,2.196,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.295029,0.00441216,0.13763 kka2_1:1_D208R,kka2_1:1_208,Kka2,kka2_1:1,P00552,0.137678,NO,208,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.708,-3.961,3.253,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.520039,0.00212588,0.137678 beta-lactamase_156_K71G,beta-lactamase_156_71,TEM-1,beta-lactamase_156,P62593,0.137738,NO,71,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-0.8,-3.358,2.558,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.111618,0.00103192,0.137738 beta-lactamase_156_K71L,beta-lactamase_156_71,TEM-1,beta-lactamase_156,P62593,0.137784,NO,71,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-0.8,-3.358,2.558,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.111618,0.00103192,0.137784 kka2_1:4_F206H,kka2_1:4_206,Kka2,kka2_1:4,P00552,0.137893,NO,206,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.349,-4.415,3.066,,0.006,E,B,0.58,-1.21,1.342,,63.64,OHH,-1.04,0.168804,0.00936868,0.137893 PSD95pdz3_H372G,PSD95pdz3_372,PSD95pdz3,PSD95pdz3,P31016,0.137907,NO,372,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-1.627,-3.04,1.413,5.5607,,,,,17.008,,,,PBA,-1.63033,0.0758425,0.00040301,0.137907 kka2_1:4_D261E,kka2_1:4_261,Kka2,kka2_1:4,P00552,0.137934,NO,261,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.708,-2.793,2.085,,0.146,G,A,0.75,-0.33,,,,HAA,-0.759333,0.168804,0.0224846,0.137934 beta-lactamase_39_I125K,beta-lactamase_39_125,TEM-1,beta-lactamase_39,P62593,0.137941,NO,125,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.441,-3.825,2.384,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.0495842,0.00383964,0.137941 beta-lactamase_625_V42P,beta-lactamase_625_42,TEM-1,beta-lactamase_625,P62593,0.137953,NO,42,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.564,-4.095,2.531,,0.017,E,B,0.44,-0.51,2.576,,63.99,BHO,-1.042,0.213352,0.00404515,0.137953 beta-lactamase_2500_P181W,beta-lactamase_2500_181,TEM-1,beta-lactamase_2500,P62593,0.137992,NO,181,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.813,-5.545,4.732,,,H,A,0.52,-1.14,1.946,,61.54,HOH,-1.795,0.361275,0.000703122,0.137992 beta-lactamase_39_T179D,beta-lactamase_39_179,TEM-1,beta-lactamase_39,P62593,0.138168,NO,179,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.085,-3.517,2.432,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.0495842,0.00226045,0.138168 kka2_1:1_V49S,kka2_1:1_49,Kka2,kka2_1:1,P00552,0.138186,NO,49,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.614,-2.896,1.282,,,E,B,0.44,-0.77,3.665,3.665,64.39,HHB,-1.3,0.520039,0.00615685,0.138186 beta-lactamase_39_S128N,beta-lactamase_39_128,TEM-1,beta-lactamase_39,P62593,0.13819,NO,128,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-0.84,-3.223,2.383,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.0495842,0.00071483,0.13819 beta-lactamase_156_G43P,beta-lactamase_156_43,TEM-1,beta-lactamase_156,P62593,0.138282,NO,43,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.62,-3.88,3.26,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.111618,0.00120151,0.138282 beta-lactamase_2500_A230T,beta-lactamase_2500_230,TEM-1,beta-lactamase_2500,P62593,0.138283,NO,230,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.154,-3.381,2.227,,0.01,E,B,0.46,-1.17,1.171,,50,HHA,-1.079,0.361275,0.00516841,0.138283 beta-lactamase_39_I261K,beta-lactamase_39_261,TEM-1,beta-lactamase_39,P62593,0.138453,NO,261,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.0495842,0.0123091,0.138453 beta-lactamase_2500_I45W,beta-lactamase_2500_45,TEM-1,beta-lactamase_2500,P62593,0.138479,NO,45,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-2.421,-5.294,2.873,,,E,B,0.48,-0.3,3.793,,77.62,HHA,-2.30267,0.361275,0.00452842,0.138479 kka2_1:2_L259H,kka2_1:2_259,Kka2,kka2_1:2,P00552,0.138562,NO,259,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.088,-4.939,3.851,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.295029,0.0206964,0.138562 beta-lactamase_V72N,beta-lactamase_72,TEM-1,beta-lactamase,P62593,0.138568,NO,72,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.658,-4.143,2.485,5.80324,,H,A,2.78,-1.03,2.964,,65.73,BHH,-1.32167,0.221079,0.00501194,0.138568 beta-lactamase_156_L136P,beta-lactamase_156_136,TEM-1,beta-lactamase_156,P62593,0.138621,NO,136,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.232,-4.152,2.92,,,H,A,0.55,-0.34,1.04,,48.95,HHH,-1.088,0.111618,0.00442304,0.138621 kka2_1:4_F256D,kka2_1:4_256,Kka2,kka2_1:4,P00552,0.13863,NO,256,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.49,-4.089,2.599,,,H,A,0.58,-0.78,1.653,,53.03,HHH,-1.423,0.168804,0.0132841,0.13863 beta-lactamase_2500_C75R,beta-lactamase_2500_75,TEM-1,beta-lactamase_2500,P62593,0.138737,NO,75,C,R,CR,Special,PositiveCharge,5.07,6.34148,1.27148,180,121,174,53,108.5,173.4,64.9,-1.245,-4.065,2.82,,,H,A,0.46,-0.87,0.844,,50,HOO,-1.24333,0.361275,0.0034616,0.138737 beta-lactamase_625_L120K,beta-lactamase_625_120,TEM-1,beta-lactamase_625,P62593,0.138786,NO,120,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.044,-3.668,2.624,,,H,A,0.55,-1.13,7.813,,64.69,AHO,-1.13633,0.213352,0.00143563,0.138786 kka2_1:2_Y22K,kka2_1:2_22,Kka2,kka2_1:2,P00552,0.138923,NO,22,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-1.583,-3.742,2.159,,0.122,.,B,0.21,-0.8,1.838,,65.53,OHA,-1.80333,0.295029,0.00598977,0.138923 beta-lactamase_2500_G240T,beta-lactamase_2500_240,TEM-1,beta-lactamase_2500,P62593,0.139004,NO,240,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.361275,0.00591201,0.139004 beta-lactamase_2500_G85P,beta-lactamase_2500_85,TEM-1,beta-lactamase_2500,P62593,0.139105,NO,85,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.011,-3.891,2.88,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.361275,0.00252173,0.139105 beta-lactamase_2500_S233E,beta-lactamase_2500_233,TEM-1,beta-lactamase_2500,P62593,0.139111,NO,233,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.886,-3.479,1.593,,0.016,E,B,0.27,-1.01,2.851,,77.62,BPO,-1.17267,0.361275,0.00311415,0.139111 kka2_1:2_L193T,kka2_1:2_193,Kka2,kka2_1:2,P00552,0.139138,NO,193,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.983,-3.533,2.55,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.295029,0.00480179,0.139138 beta-lactamase_2500_I229Q,beta-lactamase_2500_229,TEM-1,beta-lactamase_2500,P62593,0.13922,NO,229,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.267,-4.304,3.037,,0.083,E,B,0.48,-0.76,3.875,,50,HHH,-1.58767,0.361275,0.00477249,0.13922 beta-lactamase_2500_G243K,beta-lactamase_2500_243,TEM-1,beta-lactamase_2500,P62593,0.13933,NO,243,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.361275,0.00464034,0.13933 beta-lactamase_625_T158H,beta-lactamase_625_158,TEM-1,beta-lactamase_625,P62593,0.139401,NO,158,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.116,-4.689,3.573,,0.036,,B,0.22,-0.85,3.771,,69.58,HPB,-1.269,0.213352,0.00341825,0.139401 beta-lactamase_39_I245K,beta-lactamase_39_245,TEM-1,beta-lactamase_39,P62593,0.139429,NO,245,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.0495842,0.00391032,0.139429 beta-lactamase_625_T179H,beta-lactamase_625_179,TEM-1,beta-lactamase_625,P62593,0.139488,NO,179,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.085,-2.971,1.886,,,E,B,0.22,-1.38,0.367,,73.08,PPH,-1.557,0.213352,0.00226045,0.139488 kka2_1:2_D208Q,kka2_1:2_208,Kka2,kka2_1:2,P00552,0.139489,NO,208,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.708,-3.703,2.995,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.295029,0.00212588,0.139489 beta-lactamase_156_G281K,beta-lactamase_156_281,TEM-1,beta-lactamase_156,P62593,0.139531,NO,281,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.111618,0.0406482,0.139531 kka2_1:2_F263Q,kka2_1:2_263,Kka2,kka2_1:2,P00552,0.139673,NO,263,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-0.911,-4.376,3.465,,0.006,G,A,1.62,-0.12,5.275,,45.83,AHH,-0.92,0.295029,0.0172454,0.139673 beta-lactamase_2500_M115W,beta-lactamase_2500_115,TEM-1,beta-lactamase_2500,P62593,0.139677,NO,115,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.389,-5.031,3.642,,0.019,E,B,0.55,0.08,3.261,,69.58,OHP,-1.25433,0.361275,0.0034337,0.139677 kka2_1:2_E262A,kka2_1:2_262,Kka2,kka2_1:2,P00552,0.13969,NO,262,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-0.829,-3.129,2.3,,0.059,G,A,1.04,-0.18,2.383,,42.42,AAH,-0.816,0.295029,0.0191586,0.13969 kka2_1:1_F256I,kka2_1:1_256,Kka2,kka2_1:1,P00552,0.139725,NO,256,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.49,-3.685,2.195,,,H,A,1.62,-0.78,2.354,,53.03,HHH,-1.423,0.520039,0.0132841,0.139725 kka2_1:1_R140Q,kka2_1:1_140,Kka2,kka2_1:1,P00552,0.139748,NO,140,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.351,-2.5,1.149,,0.12,H,A,1.2,0.2,11.345,11.345,53.03,BBH,-1.885,0.520039,0.00430167,0.139748 beta-lactamase_2500_K71W,beta-lactamase_2500_71,TEM-1,beta-lactamase_2500,P62593,0.139884,NO,71,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-0.8,-5.322,4.522,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.361275,0.00103192,0.139884 beta-lactamase_D177Q,beta-lactamase_177,TEM-1,beta-lactamase,P62593,0.139889,NO,177,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.967,-3.799,2.832,5.08038,0.006,T,L,1.59,-1.02,3.536,,64.69,BAP,-0.873667,0.221079,0.000864022,0.139889 kka2_1:4_D190I,kka2_1:4_190,Kka2,kka2_1:4,P00552,0.1399,NO,190,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.708,-4.039,3.331,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.168804,0.00247989,0.1399 kka2_1:1_K138C,kka2_1:1_138,Kka2,kka2_1:1,P00552,0.139928,NO,138,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-2.5,-5.226,2.726,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.520039,0.00628542,0.139928 beta-lactamase_625_Y44Q,beta-lactamase_625_44,TEM-1,beta-lactamase_625,P62593,0.13995,NO,44,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-2.547,-4.196,1.649,,,E,B,0.21,-0.45,2.371,,73.78,OHH,-1.86267,0.213352,0.00426364,0.13995 kka2_1:1_L223V,kka2_1:1_223,Kka2,kka2_1:1,P00552,0.139985,NO,223,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.861,-2.827,1.966,,,H,A,0.55,-1.24,1.268,,50,HHH,-0.854333,0.520039,0.00253574,0.139985 kka2_1:4_G95F,kka2_1:4_95,Kka2,kka2_1:4,P00552,0.140056,NO,95,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-2.403,-4.378,1.975,,0.126,E,B,0.29,-0.74,0.359,,71.59,HOA,-2.198,0.168804,0.00743616,0.140056 kka2_1:2_L39H,kka2_1:2_39,Kka2,kka2_1:2,P00552,0.140077,NO,39,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.223,-4.999,3.776,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.295029,0.00493618,0.140077 beta-lactamase_2500_G234W,beta-lactamase_2500_234,TEM-1,beta-lactamase_2500,P62593,0.140106,NO,234,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.62,-5.097,4.477,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.361275,0.000889577,0.140106 beta-lactamase_2500_V259Q,beta-lactamase_2500_259,TEM-1,beta-lactamase_2500,P62593,0.140142,NO,259,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.361275,0.0070773,0.140142 beta-lactamase_M1E,beta-lactamase_1,TEM-1,beta-lactamase,P62593,0.140145,NO,1,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.998,-3.347,1.349,,,,,,,,,,OHP,-1.97,0.221079,0.00162771,0.140145 beta-lactamase_S240W,beta-lactamase_240,TEM-1,beta-lactamase,P62593,0.140145,NO,240,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.537,-5.368,3.831,4.75024,,,B,0.74,-0.74,0.357,,65.38,OPB,-1.263,0.221079,0.00591201,0.140145 beta-lactamase_156_G243W,beta-lactamase_156_243,TEM-1,beta-lactamase_156,P62593,0.140167,NO,243,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.532,,,,,E,B,0.77,-1.24,2.866,,50,BOH,-1.46867,0.111618,0.00464034,0.140167 beta-lactamase_39_C75F,beta-lactamase_39_75,TEM-1,beta-lactamase_39,P62593,0.140185,NO,75,C,F,CF,Special,Hydrophobic,5.07,3.32051,-1.74949,205,121,165,44,108.5,189.9,81.4,-1.245,-4.17,2.925,,,H,A,0.46,-0.87,2.369,,50,HOO,-1.24333,0.0495842,0.0034616,0.140185 kka2_1:4_D261H,kka2_1:4_261,Kka2,kka2_1:4,P00552,0.140198,NO,261,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.708,-4.483,3.775,,0.146,G,A,0.75,-0.33,,,,HAA,-0.759333,0.168804,0.0224846,0.140198 kka2_1:4_E262H,kka2_1:4_262,Kka2,kka2_1:4,P00552,0.140202,NO,262,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-0.829,-4.282,3.453,,0.059,G,A,1.04,-0.18,2.383,,42.42,AAH,-0.816,0.168804,0.0191586,0.140202 kka2_1:2_A78L,kka2_1:2_78,Kka2,kka2_1:2,P00552,0.140216,NO,78,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.744,-3.506,1.762,,0.078,.,B,0.46,-0.53,0.206,,56.06,OHH,-1.863,0.295029,0.00457299,0.140216 kka2_1:4_G205W,kka2_1:4_205,Kka2,kka2_1:4,P00552,0.140219,NO,205,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.596,-5.126,4.53,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.168804,0.00221855,0.140219 beta-lactamase_2500_A235Y,beta-lactamase_2500_235,TEM-1,beta-lactamase_2500,P62593,0.140273,NO,235,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.266,-4.294,3.028,,0.32,E,B,0.46,-0.86,0.891,,50,OHO,-0.89,0.361275,0.00493474,0.140273 kka2_1:2_F203M,kka2_1:2_203,Kka2,kka2_1:2,P00552,0.140302,NO,203,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-0.911,-4.239,3.328,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.295029,0.00318738,0.140302 kka2_1:4_G189N,kka2_1:4_189,Kka2,kka2_1:4,P00552,0.140386,NO,189,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.596,-3.476,2.88,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.168804,0.00253688,0.140386 beta-lactamase_2500_I280S,beta-lactamase_2500_280,TEM-1,beta-lactamase_2500,P62593,0.140452,NO,280,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.361275,0.0530888,0.140452 beta-lactamase_625_M184D,beta-lactamase_625_184,TEM-1,beta-lactamase_625,P62593,0.140599,NO,184,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.593,-3.936,2.343,,,H,A,0.55,-0.87,2.765,,62.94,HHH,-1.41,0.213352,0.00356019,0.140599 beta-lactamase_2500_L74W,beta-lactamase_2500_74,TEM-1,beta-lactamase_2500,P62593,0.140712,NO,74,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.296,-5.261,3.965,,,H,A,0.55,-0.91,0.746,,50,HHO,-1.34933,0.361275,0.00493255,0.140712 kka2_1:2_L223G,kka2_1:2_223,Kka2,kka2_1:2,P00552,0.140715,NO,223,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.861,-3.881,3.02,,,H,A,0.55,-1.24,0.266,,50,HHH,-0.854333,0.295029,0.00253574,0.140715 kka2_1:2_F206Y,kka2_1:2_206,Kka2,kka2_1:2,P00552,0.140798,NO,206,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.349,-1.759,0.41,,0.006,E,B,0.58,-1.21,0.978,,63.64,OHH,-1.04,0.295029,0.00936868,0.140798 kka2_1:4_E96Y,kka2_1:4_96,Kka2,kka2_1:4,P00552,0.140798,NO,96,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.573,-4.313,1.74,,0.476,,B,1.52,-0.65,1.254,,71.59,OAH,-2.143,0.168804,0.00369441,0.140798 beta-lactamase_156_A185P,beta-lactamase_156_185,TEM-1,beta-lactamase_156,P62593,0.140835,NO,185,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.406,-2.861,1.455,,,H,A,0.46,-1.02,0.365,,65.03,HHP,-1.84033,0.111618,0.00467449,0.140835 beta-lactamase_156_S68R,beta-lactamase_156_68,TEM-1,beta-lactamase_156,P62593,0.140845,NO,68,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-0.913,-3.705,2.792,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.111618,0.000800065,0.140845 kka2_1:1_D261E,kka2_1:1_261,Kka2,kka2_1:1,P00552,0.140847,NO,261,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.708,-2.793,2.085,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.520039,0.0224846,0.140847 kka2_1:1_G210W,kka2_1:1_210,Kka2,kka2_1:1,P00552,0.140871,NO,210,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.095,-5.322,4.227,,0.103,T,A,0.29,-0.62,14.483,14.483,50,OOB,-0.966667,0.520039,0.00598378,0.140871 beta-lactamase_625_I244G,beta-lactamase_625_244,TEM-1,beta-lactamase_625,P62593,0.140888,NO,244,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.555,-3.714,2.159,,,E,B,0.48,-0.84,2.061,,77.62,OHH,-1.385,0.213352,0.00605379,0.140888 PSD95pdz3_S361P,PSD95pdz3_361,PSD95pdz3,PSD95pdz3,P31016,0.140898,NO,361,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.519,-3.336,1.817,4.8722,,,,,16.4533,,,,HPH,-1.47167,0.0758425,0.00055296,0.140898 beta-lactamase_C121F,beta-lactamase_121,TEM-1,beta-lactamase,P62593,0.141012,NO,121,C,F,CF,Special,Hydrophobic,5.07,3.32051,-1.74949,205,121,165,44,108.5,189.9,81.4,-0.953,-4.116,3.163,5.12205,,H,A,2.8,-0.81,7.644,,63.29,HOP,-1.46767,0.221079,0.000744322,0.141012 kka2_1:2_P109I,kka2_1:2_109,Kka2,kka2_1:2,P00552,0.141042,NO,109,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.412,-3.963,2.551,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.295029,0.0070929,0.141042 beta-lactamase_625_G249P,beta-lactamase_625_249,TEM-1,beta-lactamase_625,P62593,0.141047,NO,249,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.312,-2.663,1.351,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.213352,0.00220169,0.141047 kka2_1:2_G99Q,kka2_1:2_99,Kka2,kka2_1:2,P00552,0.141079,NO,99,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.596,-4.153,3.557,,0.368,S,g,0.29,-0.87,,,,OOP,-1.63067,0.295029,0.00186055,0.141079 beta-lactamase_625_G76P,beta-lactamase_625_76,TEM-1,beta-lactamase_625,P62593,0.14111,NO,76,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.189,-3.852,2.663,,,H,A,0.29,-0.67,3.059,,67.83,OOH,-1.22267,0.213352,0.00476637,0.14111 kka2_1:4_W69V,kka2_1:4_69,Kka2,kka2_1:4,P00552,0.141131,NO,69,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-0.859,-3.749,2.89,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.168804,0.0012874,0.141131 beta-lactamase_2500_G234R,beta-lactamase_2500_234,TEM-1,beta-lactamase_2500,P62593,0.141152,NO,234,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.62,-3.933,3.313,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.361275,0.000889577,0.141152 kka2_1:1_L102I,kka2_1:1_102,Kka2,kka2_1:1,P00552,0.141153,NO,102,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.804,-2.957,2.153,,,T,A,0.55,-1.17,4.258,,42.42,AHH,-1.398,0.520039,0.00201332,0.141153 beta-lactamase_625_T158P,beta-lactamase_625_158,TEM-1,beta-lactamase_625,P62593,0.141175,NO,158,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.116,-2.676,1.56,,0.036,,B,0.22,-0.85,3.771,,69.58,HPB,-1.269,0.213352,0.00341825,0.141175 kka2_1:4_D208I,kka2_1:4_208,Kka2,kka2_1:4,P00552,0.141177,NO,208,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.708,-4.039,3.331,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.168804,0.00212588,0.141177 beta-lactamase_625_A124F,beta-lactamase_625_124,TEM-1,beta-lactamase_625,P62593,0.141197,NO,124,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.181,-4.133,2.952,,,H,A,0.46,-0.9,2.027,,64.34,HHH,-1.152,0.213352,0.00481399,0.141197 kka2_1:1_G233F,kka2_1:1_233,Kka2,kka2_1:1,P00552,0.141261,NO,233,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.748,-4.365,3.617,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.520039,0.00232366,0.141261 kka2_1:4_L223F,kka2_1:4_223,Kka2,kka2_1:4,P00552,0.141326,NO,223,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.861,-3.69,2.829,,,H,A,1.59,-1.24,1.268,,50,HHH,-0.854333,0.168804,0.00253574,0.141326 beta-lactamase_156_V260H,beta-lactamase_156_260,TEM-1,beta-lactamase_156,P62593,0.14133,NO,260,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.111618,0.00471757,0.14133 kka2_1:2_T187Q,kka2_1:2_187,Kka2,kka2_1:2,P00552,0.141342,NO,187,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.273,-4.098,2.825,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.295029,0.00693073,0.141342 kka2_1:1_I221R,kka2_1:1_221,Kka2,kka2_1:1,P00552,0.141356,NO,221,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.739,-4.17,2.431,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.520039,0.00945908,0.141356 beta-lactamase_G236R,beta-lactamase_236,TEM-1,beta-lactamase,P62593,0.141377,NO,236,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.784,-3.932,3.148,4.7915,0.241,,b,0.23,-0.59,1.883,,64.69,HOA,-1.36933,0.221079,0.00162372,0.141377 beta-lactamase_2500_R176P,beta-lactamase_2500_176,TEM-1,beta-lactamase_2500,P62593,0.141378,NO,176,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-0.863,-3.88,3.017,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.361275,0.00105554,0.141378 beta-lactamase_625_M67P,beta-lactamase_625_67,TEM-1,beta-lactamase_625,P62593,0.141381,NO,67,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-2.231,-4.072,1.841,,0.006,G,P,0.55,-0.81,2.653,,65.03,HHP,-1.502,0.213352,0.00409753,0.141381 beta-lactamase_39_A132N,beta-lactamase_39_132,TEM-1,beta-lactamase_39,P62593,0.141384,NO,132,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.9,-3.872,2.972,,,H,A,0.46,-0.93,8.408,,64.69,PHH,-1.138,0.0495842,0.000962524,0.141384 beta-lactamase_2500_L120Y,beta-lactamase_2500_120,TEM-1,beta-lactamase_2500,P62593,0.141403,NO,120,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.044,-3.856,2.812,,,H,A,0.55,-1.13,2.48,,64.69,AHO,-1.13633,0.361275,0.00143563,0.141403 beta-lactamase_156_A132N,beta-lactamase_156_132,TEM-1,beta-lactamase_156,P62593,0.141458,NO,132,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.9,-3.872,2.972,,,H,A,0.46,-0.93,10.621,,64.69,PHH,-1.138,0.111618,0.000962524,0.141458 kka2_1:4_L232G,kka2_1:4_232,Kka2,kka2_1:4,P00552,0.141513,NO,232,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.514,-2.969,1.455,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.168804,0.00800103,0.141513 beta-lactamase_156_F64K,beta-lactamase_156_64,TEM-1,beta-lactamase_156,P62593,0.141588,NO,64,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-0.841,-3.907,3.066,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.111618,0.000947691,0.141588 kka2_1:1_R226F,kka2_1:1_226,Kka2,kka2_1:1,P00552,0.141614,NO,226,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.392,-4.163,2.771,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.520039,0.0108032,0.141614 beta-lactamase_156_K71S,beta-lactamase_156_71,TEM-1,beta-lactamase_156,P62593,0.141728,NO,71,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-0.8,-3.161,2.361,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.111618,0.00103192,0.141728 beta-lactamase_156_S68P,beta-lactamase_156_68,TEM-1,beta-lactamase_156,P62593,0.141733,NO,68,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-0.913,-3.704,2.791,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.111618,0.000800065,0.141733 kka2_1:2_F264Q,kka2_1:2_264,Kka2,kka2_1:2,P00552,0.141734,NO,264,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.02,-4.325,3.305,,0.296,.,?,0.58,0.02,2.303,,71.59,HHNA,-0.9655,0.295029,,0.141734 beta-lactamase_2500_D174F,beta-lactamase_2500_174,TEM-1,beta-lactamase_2500,P62593,0.141737,NO,174,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.738,-4.292,3.554,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.361275,0.00125633,0.141737 beta-lactamase_2500_T131I,beta-lactamase_2500_131,TEM-1,beta-lactamase_2500,P62593,0.141742,NO,131,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.328,-3.758,2.43,,,H,A,0.22,-0.69,3.048,,67.48,PPH,-1.00867,0.361275,0.00345886,0.141742 beta-lactamase_625_I261H,beta-lactamase_625_261,TEM-1,beta-lactamase_625,P62593,0.141742,NO,261,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.213352,0.0123091,0.141742 beta-lactamase_2500_V31F,beta-lactamase_2500_31,TEM-1,beta-lactamase_2500,P62593,0.14189,NO,31,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.822,-2.736,0.914,,,H,A,0.44,-0.46,0.955,,73.78,BHB,-2.03767,0.361275,0.00478065,0.14189 beta-lactamase_2500_I261Q,beta-lactamase_2500_261,TEM-1,beta-lactamase_2500,P62593,0.141913,NO,261,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.361275,0.0123091,0.141913 kka2_1:1_W236Y,kka2_1:1_236,Kka2,kka2_1:1,P00552,0.141966,NO,236,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-1.363,-2.865,1.502,,0.303,H,A,1.51,-0.76,12.263,12.263,48.48,AHH,-1.81267,0.520039,0.0088796,0.141966 beta-lactamase_2500_T69Y,beta-lactamase_2500_69,TEM-1,beta-lactamase_2500,P62593,0.142004,NO,69,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-0.973,-4.223,3.25,,,G,A,0.22,-1.24,2.05,,93.01,PPH,-1.01833,0.361275,0.00127498,0.142004 beta-lactamase_T193P,beta-lactamase_193,TEM-1,beta-lactamase,P62593,0.14201,NO,193,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.914,-4.072,2.158,5.67952,0.439,H,a,0.3,0.33,1.863,,63.99,HPO,-1.52133,0.221079,0.00482669,0.14201 beta-lactamase_2500_V259P,beta-lactamase_2500_259,TEM-1,beta-lactamase_2500,P62593,0.142119,NO,259,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.361275,0.0070773,0.142119 beta-lactamase_156_S128I,beta-lactamase_156_128,TEM-1,beta-lactamase_156,P62593,0.142136,NO,128,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-0.84,-3.785,2.945,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.111618,0.00071483,0.142136 beta-lactamase_2500_G240L,beta-lactamase_2500_240,TEM-1,beta-lactamase_2500,P62593,0.142142,NO,240,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.361275,0.00591201,0.142142 kka2_1:4_V198N,kka2_1:4_198,Kka2,kka2_1:4,P00552,0.14217,NO,198,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.719,-3.977,2.258,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.168804,0.00835002,0.14217 kka2_1:1_P249H,kka2_1:1_249,Kka2,kka2_1:1,P00552,0.14218,NO,249,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.867,-4.971,3.104,,0.406,.,B,0.52,-0.01,8.037,8.037,92.05,HOA,-1.66867,0.520039,0.011045,0.14218 beta-lactamase_156_P181F,beta-lactamase_156_181,TEM-1,beta-lactamase_156,P62593,0.142236,NO,181,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.813,-4.48,3.667,,,H,A,0.52,-1.14,1.078,,61.54,HOH,-1.795,0.111618,0.000703122,0.142236 kka2_1:1_G95E,kka2_1:1_95,Kka2,kka2_1:1,P00552,0.142245,NO,95,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-2.403,-2.685,0.282,,0.126,E,B,0.29,-0.74,7.822,,71.59,HOA,-2.198,0.520039,0.00743616,0.142245 beta-lactamase_156_G249M,beta-lactamase_156_249,TEM-1,beta-lactamase_156,P62593,0.14225,NO,249,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.111618,0.00220169,0.14225 beta-lactamase_625_L191K,beta-lactamase_625_191,TEM-1,beta-lactamase_625,P62593,0.142271,NO,191,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.087,-3.741,2.654,,,H,A,0.55,0.09,1.908,,63.29,BHH,-1.445,0.213352,0.00263549,0.142271 kka2_1:2_L243I,kka2_1:2_243,Kka2,kka2_1:2,P00552,0.142322,NO,243,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-2.651,-3.227,0.576,,0.277,H,A,1.59,-0.67,13.165,13.165,92.05,HHH,-2.03767,0.295029,0.00884927,0.142322 beta-lactamase_F64K,beta-lactamase_64,TEM-1,beta-lactamase,P62593,0.142327,NO,64,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-0.841,-3.907,3.066,5.70769,0.006,E,B,1.33,-0.95,,,,BHO,-0.892667,0.221079,0.000947691,0.142327 beta-lactamase_625_L205P,beta-lactamase_625_205,TEM-1,beta-lactamase_625,P62593,0.142332,NO,205,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.922,-4.159,3.237,,,H,A,0.55,-0.46,3.782,,42.31,PHH,-1.57767,0.213352,0.00255802,0.142332 beta-lactamase_156_A133R,beta-lactamase_156_133,TEM-1,beta-lactamase_156,P62593,0.142347,NO,133,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.186,-3.865,2.679,,,H,A,0.46,-0.86,0.805,,67.83,HHP,-0.988333,0.111618,0.00468022,0.142347 kka2_1:1_W91P,kka2_1:1_91,Kka2,kka2_1:1,P00552,0.142463,NO,91,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-1.178,-4.336,3.158,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.520039,0.00358653,0.142463 kka2_1:4_G189K,kka2_1:4_189,Kka2,kka2_1:4,P00552,0.142491,NO,189,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.596,-3.71,3.114,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.168804,0.00253688,0.142491 beta-lactamase_156_A230P,beta-lactamase_156_230,TEM-1,beta-lactamase_156,P62593,0.142539,NO,230,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.154,-3.805,2.651,,0.01,E,B,0.46,-1.17,2.179,,50,HHA,-1.079,0.111618,0.00516841,0.142539 kka2_1:2_I207K,kka2_1:2_207,Kka2,kka2_1:2,P00552,0.14254,NO,207,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.175,-3.925,2.75,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.295029,0.00611824,0.14254 kka2_1:2_I228Y,kka2_1:2_228,Kka2,kka2_1:2,P00552,0.142547,NO,228,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.142,-4.038,2.896,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.295029,0.00458834,0.142547 kka2_1:8_G213H,kka2_1:8_213,Kka2,kka2_1:8,P00552,0.142569,NO,213,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.596,-4.708,4.112,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.100394,0.00187654,0.142569 kka2_1:8_G213H,kka2_1:8_213,Kka2,kka2_1:8,P00552,0.142569,NO,213,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.596,-4.708,4.112,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.100394,0.00187654,0.142569 beta-lactamase_39_S128I,beta-lactamase_39_128,TEM-1,beta-lactamase_39,P62593,0.142582,NO,128,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-0.84,-3.785,2.945,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.0495842,0.00071483,0.142582 beta-lactamase_156_D177L,beta-lactamase_156_177,TEM-1,beta-lactamase_156,P62593,0.142602,NO,177,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.967,-3.772,2.805,,0.006,T,L,0.75,-1.02,2.072,,64.69,BAP,-0.873667,0.111618,0.000864022,0.142602 beta-lactamase_G248Y,beta-lactamase_248,TEM-1,beta-lactamase,P62593,0.142641,NO,248,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.794,-3.966,2.172,4.69798,,E,b,0.23,-0.43,1.782,,61.19,HOO,-1.52867,0.221079,0.00428493,0.142641 kka2_1:1_V198Y,kka2_1:1_198,Kka2,kka2_1:1,P00552,0.142658,NO,198,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.719,-4.264,2.545,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.520039,0.00835002,0.142658 kka2_1:1_T72I,kka2_1:1_72,Kka2,kka2_1:1,P00552,0.142663,NO,72,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.38,-4.117,1.737,,0.784,H,A,0.22,0.29,10.43,10.43,65.53,HPP,-2.238,0.520039,0.00750756,0.142663 beta-lactamase_2500_I45P,beta-lactamase_2500_45,TEM-1,beta-lactamase_2500,P62593,0.142693,NO,45,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-2.421,-4.091,1.67,,,E,B,0.48,-0.3,3.793,,77.62,HHA,-2.30267,0.361275,0.00452842,0.142693 kka2_1:4_H188K,kka2_1:4_188,Kka2,kka2_1:4,P00552,0.142784,NO,188,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-0.913,-3.453,2.54,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.168804,0.00273139,0.142784 kka2_1:8_F256G,kka2_1:8_256,Kka2,kka2_1:8,P00552,0.142793,NO,256,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.49,-3.713,2.223,,,H,A,1.62,-0.78,1.713,,53.03,HHH,-1.423,0.100394,0.0132841,0.142793 kka2_1:8_F256G,kka2_1:8_256,Kka2,kka2_1:8,P00552,0.142793,NO,256,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.49,-3.713,2.223,,,H,A,1.62,-0.78,1.713,,53.03,HHH,-1.423,0.100394,0.0132841,0.142793 kka2_1:1_N200P,kka2_1:1_200,Kka2,kka2_1:1,P00552,0.142797,NO,200,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-2.446,-4.046,1.6,,0.756,T,L,0.61,-0.08,17.299,17.299,64.39,APO,-2.08,0.520039,0.00838549,0.142797 beta-lactamase_625_E164R,beta-lactamase_625_164,TEM-1,beta-lactamase_625,P62593,0.142826,NO,164,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-0.948,-3.511,2.563,,0.011,T,B,1.04,-0.4,1.321,,64.69,HAO,-1.388,0.213352,0.00137286,0.142826 kka2_1:2_L212A,kka2_1:2_212,Kka2,kka2_1:2,P00552,0.14289,NO,212,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.904,-2.253,1.349,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.295029,0.0031426,0.14289 kka2_1:4_D208S,kka2_1:4_208,Kka2,kka2_1:4,P00552,0.142908,NO,208,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.708,-3.189,2.481,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.168804,0.00212588,0.142908 PSD95pdz3_I388E,PSD95pdz3_388,PSD95pdz3,PSD95pdz3,P31016,0.142954,NO,388,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.63,-3.572,1.942,5.17282,,,,,16.0025,,,,PHH,-1.54967,0.0758425,0.000151216,0.142954 beta-lactamase_625_V31W,beta-lactamase_625_31,TEM-1,beta-lactamase_625,P62593,0.143109,NO,31,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.822,-5.287,3.465,,,H,A,0.44,-0.46,2.576,,73.78,BHB,-2.03767,0.213352,0.00478065,0.143109 beta-lactamase_W286C,beta-lactamase_286,TEM-1,beta-lactamase,P62593,0.143114,NO,286,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-1.111,-4.679,3.568,6.64456,0.492,,?,0.01,0.6,,,,BHX,-1.478,0.221079,,0.143114 kka2_1:2_Q219D,kka2_1:2_219,Kka2,kka2_1:2,P00552,0.143129,NO,219,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-0.93,-3.333,2.403,,0.088,H,A,0.4,-0.85,1.917,,50,HPA,-1.05167,0.295029,0.00237913,0.143129 kka2_1:2_L232C,kka2_1:2_232,Kka2,kka2_1:2,P00552,0.143144,NO,232,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.514,-3.424,1.91,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.295029,0.00800103,0.143144 beta-lactamase_2500_E119P,beta-lactamase_2500_119,TEM-1,beta-lactamase_2500,P62593,0.143172,NO,119,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.412,-3.828,2.416,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.361275,0.00386966,0.143172 kka2_1:1_K112C,kka2_1:1_112,Kka2,kka2_1:1,P00552,0.143174,NO,112,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-2.491,-3.546,1.055,,0.076,H,A,2.34,-1.37,23.433,23.433,56.06,ABH,-2.00133,0.520039,0.00645389,0.143174 kka2_1:1_T73Y,kka2_1:1_73,Kka2,kka2_1:1,P00552,0.1432,NO,73,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.51,-3.328,0.818,,0.309,H,A,0.22,0.35,4.126,,56.06,PPO,-2.02333,0.520039,0.00628605,0.1432 beta-lactamase_2500_D33P,beta-lactamase_2500_33,TEM-1,beta-lactamase_2500,P62593,0.143208,NO,33,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.321,-3.968,1.647,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.361275,0.00435556,0.143208 kka2_1:1_A191W,kka2_1:1_191,Kka2,kka2_1:1,P00552,0.143248,NO,191,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.831,-5.414,4.583,,,.,b,0.46,-0.94,0.53,,50,AHO,-0.868667,0.520039,0.00338807,0.143248 beta-lactamase_39_A124W,beta-lactamase_39_124,TEM-1,beta-lactamase_39,P62593,0.143249,NO,124,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.181,-5.322,4.141,,,H,A,0.46,-0.9,1.367,,64.34,HHH,-1.152,0.0495842,0.00481399,0.143249 beta-lactamase_0_V117R,beta-lactamase_0_117,TEM-1,beta-lactamase_0,P62593,0.143293,NO,117,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.53,-4.17,2.64,,,H,A,0.44,-0.34,1.16,,65.03,PHB,-1.741,0.0500837,0.00467906,0.143293 beta-lactamase_625_K71P,beta-lactamase_625_71,TEM-1,beta-lactamase_625,P62593,0.143355,NO,71,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-0.8,-3.655,2.855,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.213352,0.00103192,0.143355 beta-lactamase_A133H,beta-lactamase_133,TEM-1,beta-lactamase,P62593,0.143359,NO,133,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.186,-4.769,3.583,4.86423,,H,A,0.55,-0.86,2.649,,67.83,HHP,-0.988333,0.221079,0.00468022,0.143359 beta-lactamase_L136N,beta-lactamase_136,TEM-1,beta-lactamase,P62593,0.14337,NO,136,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.232,-4.217,2.985,5.31114,,H,A,2.89,-0.34,1.539,,48.95,HHH,-1.088,0.221079,0.00442304,0.14337 beta-lactamase_2500_I229R,beta-lactamase_2500_229,TEM-1,beta-lactamase_2500,P62593,0.143421,NO,229,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.267,-4.174,2.907,,0.083,E,B,0.48,-0.76,3.875,,50,HHH,-1.58767,0.361275,0.00477249,0.143421 beta-lactamase_625_R59I,beta-lactamase_625_59,TEM-1,beta-lactamase_625,P62593,0.143433,NO,59,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.345,-4.065,2.72,,0.329,S,L,1.2,-0.09,2.995,,73.08,HBO,-2.24267,0.213352,0.00318082,0.143433 beta-lactamase_D177V,beta-lactamase_177,TEM-1,beta-lactamase,P62593,0.143444,NO,177,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.967,-3.739,2.772,5.08038,0.006,T,L,1.59,-1.02,3.536,,64.69,BAP,-0.873667,0.221079,0.000864022,0.143444 kka2_1:1_D101I,kka2_1:1_101,Kka2,kka2_1:1,P00552,0.143497,NO,101,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.028,-3.84,2.812,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.520039,0.00423361,0.143497 beta-lactamase_2500_E164K,beta-lactamase_2500_164,TEM-1,beta-lactamase_2500,P62593,0.143526,NO,164,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-0.948,-2.425,1.477,,0.011,T,B,1.04,-0.4,0.352,,64.69,HAO,-1.388,0.361275,0.00137286,0.143526 beta-lactamase_625_V259W,beta-lactamase_625_259,TEM-1,beta-lactamase_625,P62593,0.143671,NO,259,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.213352,0.0070773,0.143671 kka2_1:1_L241E,kka2_1:1_241,Kka2,kka2_1:1,P00552,0.143775,NO,241,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.158,-4.005,2.847,,0.08,H,A,0.55,-0.82,1.685,,63.26,HHH,-1.58533,0.520039,0.0117299,0.143775 kka2_1:1_M116S,kka2_1:1_116,Kka2,kka2_1:1,P00552,0.143775,NO,116,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-2.482,-3.643,1.161,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.520039,0.00745147,0.143775 kka2_1:4_H188F,kka2_1:4_188,Kka2,kka2_1:4,P00552,0.143862,NO,188,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-0.913,-3.931,3.018,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.168804,0.00273139,0.143862 kka2_1:2_Y244Q,kka2_1:2_244,Kka2,kka2_1:2,P00552,0.143895,NO,244,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-0.775,-3.928,3.153,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.295029,0.00453187,0.143895 beta-lactamase_625_L223E,beta-lactamase_625_223,TEM-1,beta-lactamase_625,P62593,0.143909,NO,223,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.055,-3.868,2.813,,0.27,,B,0.55,0.09,1.633,,74.48,HHO,-1.35033,0.213352,0.00372793,0.143909 beta-lactamase_625_L135P,beta-lactamase_625_135,TEM-1,beta-lactamase_625,P62593,0.144029,NO,135,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.002,-4.134,3.132,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.213352,0.00244423,0.144029 beta-lactamase_2500_S68Q,beta-lactamase_2500_68,TEM-1,beta-lactamase_2500,P62593,0.144067,NO,68,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-0.913,-3.7,2.787,,0.064,G,A,0.27,-1.03,2.824,,64.69,HPP,-1.37233,0.361275,0.000800065,0.144067 kka2_1:1_F206D,kka2_1:1_206,Kka2,kka2_1:1,P00552,0.144071,NO,206,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.349,-4.082,2.733,,0.006,E,B,0.58,-1.21,0.978,,63.64,OHH,-1.04,0.520039,0.00936868,0.144071 beta-lactamase_156_M184D,beta-lactamase_156_184,TEM-1,beta-lactamase_156,P62593,0.14413,NO,184,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.593,-3.936,2.343,,,H,A,0.55,-0.87,1.671,,62.94,HHH,-1.41,0.111618,0.00356019,0.14413 beta-lactamase_2500_M127P,beta-lactamase_2500_127,TEM-1,beta-lactamase_2500,P62593,0.144131,NO,127,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-2.251,-4.144,1.893,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.361275,0.00437927,0.144131 beta-lactamase_2500_L167Y,beta-lactamase_2500_167,TEM-1,beta-lactamase_2500,P62593,0.144149,NO,167,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.138,-4.067,2.929,,0.015,G,A,0.55,-0.63,7.813,,64.69,AHP,-1.30767,0.361275,0.00303566,0.144149 kka2_1:1_V80H,kka2_1:1_80,Kka2,kka2_1:1,P00552,0.144203,NO,80,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.144,-4.98,3.836,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.520039,0.00488211,0.144203 beta-lactamase_625_A230P,beta-lactamase_625_230,TEM-1,beta-lactamase_625,P62593,0.144436,NO,230,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.154,-3.805,2.651,,0.01,E,B,0.46,-1.17,0.777,,50,HHA,-1.079,0.213352,0.00516841,0.144436 kka2_1:2_V186E,kka2_1:2_186,Kka2,kka2_1:2,P00552,0.144446,NO,186,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.011,-3.841,2.83,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.295029,0.00409703,0.144446 beta-lactamase_2500_V31W,beta-lactamase_2500_31,TEM-1,beta-lactamase_2500,P62593,0.144504,NO,31,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.822,-5.287,3.465,,,H,A,0.44,-0.46,0.955,,73.78,BHB,-2.03767,0.361275,0.00478065,0.144504 kka2_1:1_A172I,kka2_1:1_172,Kka2,kka2_1:1,P00552,0.144532,NO,172,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.757,-3.215,1.458,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.520039,0.0079265,0.144532 kka2_1:4_I228W,kka2_1:4_228,Kka2,kka2_1:4,P00552,0.144562,NO,228,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.142,-5.373,4.231,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.168804,0.00458834,0.144562 beta-lactamase_625_A133I,beta-lactamase_625_133,TEM-1,beta-lactamase_625,P62593,0.144577,NO,133,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.186,-3.823,2.637,,,H,A,0.46,-0.86,0.373,,67.83,HHP,-0.988333,0.213352,0.00468022,0.144577 kka2_1:8_V113P,kka2_1:8_113,Kka2,kka2_1:8,P00552,0.144577,NO,113,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.233,-4.102,2.869,,0.008,H,A,1.48,-1.17,1.254,,52.27,BHP,-2.08367,0.100394,0.00650191,0.144577 kka2_1:8_V113P,kka2_1:8_113,Kka2,kka2_1:8,P00552,0.144577,NO,113,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.233,-4.102,2.869,,0.008,H,A,1.48,-1.17,1.254,,52.27,BHP,-2.08367,0.100394,0.00650191,0.144577 beta-lactamase_156_I261R,beta-lactamase_156_261,TEM-1,beta-lactamase_156,P62593,0.14461,NO,261,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.111618,0.0123091,0.14461 beta-lactamase_2500_I229D,beta-lactamase_2500_229,TEM-1,beta-lactamase_2500,P62593,0.144658,NO,229,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.267,-3.973,2.706,,0.083,E,B,0.48,-0.76,3.875,,50,HHH,-1.58767,0.361275,0.00477249,0.144658 kka2_1:1_L223W,kka2_1:1_223,Kka2,kka2_1:1,P00552,0.144676,NO,223,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.861,-5.208,4.347,,,H,A,0.55,-1.24,1.268,,50,HHH,-0.854333,0.520039,0.00253574,0.144676 beta-lactamase_E119I,beta-lactamase_119,TEM-1,beta-lactamase,P62593,0.144677,NO,119,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.412,-4.096,2.684,5.33349,0.358,H,A,1.52,0.51,1.983,,63.99,BAH,-1.623,0.221079,0.00386966,0.144677 beta-lactamase_156_K71F,beta-lactamase_156_71,TEM-1,beta-lactamase_156,P62593,0.144681,NO,71,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-0.8,-4.292,3.492,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.111618,0.00103192,0.144681 kka2_1:1_Y218P,kka2_1:1_218,Kka2,kka2_1:1,P00552,0.144739,NO,218,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-1.438,-4.207,2.769,,0.122,H,A,1.25,-0.69,3.059,,56.06,BHP,-1.17533,0.520039,0.0126098,0.144739 kka2_1:1_F256G,kka2_1:1_256,Kka2,kka2_1:1,P00552,0.144754,NO,256,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.49,-3.713,2.223,,,H,A,1.62,-0.78,2.354,,53.03,HHH,-1.423,0.520039,0.0132841,0.144754 beta-lactamase_2500_D83Y,beta-lactamase_2500_83,TEM-1,beta-lactamase_2500,P62593,0.144844,NO,83,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.066,-4.396,3.33,,0.354,H,A,0.75,0.22,0.239,,48.95,HAH,-1.34733,0.361275,0.00205968,0.144844 beta-lactamase_2500_G243V,beta-lactamase_2500_243,TEM-1,beta-lactamase_2500,P62593,0.14488,NO,243,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.361275,0.00464034,0.14488 kka2_1:2_R226K,kka2_1:2_226,Kka2,kka2_1:2,P00552,0.144897,NO,226,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.392,-3.285,1.893,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.295029,0.0108032,0.144897 beta-lactamase_2500_D155F,beta-lactamase_2500_155,TEM-1,beta-lactamase_2500,P62593,0.145012,NO,155,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.889,-4.341,3.452,,0.049,,B,0.75,-0.9,2.386,,64.69,OAB,-1.62267,0.361275,0.00135315,0.145012 kka2_1:8_M197E,kka2_1:8_197,Kka2,kka2_1:8,P00552,0.145021,NO,197,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.707,-3.927,2.22,,0.121,E,B,1.59,-1.19,4.408,,65.53,HHH,-1.847,0.100394,0.00921295,0.145021 kka2_1:8_M197E,kka2_1:8_197,Kka2,kka2_1:8,P00552,0.145021,NO,197,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.707,-3.927,2.22,,0.121,E,B,1.59,-1.19,4.408,,65.53,HHH,-1.847,0.100394,0.00921295,0.145021 kka2_1:1_P167E,kka2_1:1_167,Kka2,kka2_1:1,P00552,0.145023,NO,167,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-2.403,-3.663,1.26,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.520039,0.00543203,0.145023 beta-lactamase_156_W227E,beta-lactamase_156_227,TEM-1,beta-lactamase_156,P62593,0.145058,NO,227,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-0.982,-3.914,2.932,,0.272,,B,0.47,-0.29,2.533,,74.48,OHH,-1.595,0.111618,0.00226019,0.145058 beta-lactamase_2500_E164Y,beta-lactamase_2500_164,TEM-1,beta-lactamase_2500,P62593,0.145077,NO,164,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-0.948,-4.233,3.285,,0.011,T,B,1.04,-0.4,0.352,,64.69,HAO,-1.388,0.361275,0.00137286,0.145077 kka2_1:1_F133H,kka2_1:1_133,Kka2,kka2_1:1,P00552,0.145093,NO,133,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-0.871,-4.414,3.543,,0.178,.,B,0.58,0.43,1.999,,42.42,OHA,-0.871667,0.520039,0.00182168,0.145093 beta-lactamase_2500_L137W,beta-lactamase_2500_137,TEM-1,beta-lactamase_2500,P62593,0.145115,NO,137,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.03,-5.164,4.134,,,H,A,0.55,-0.38,0.769,,42.31,HHP,-1.58933,0.361275,0.00278599,0.145115 kka2_1:1_D220K,kka2_1:1_220,Kka2,kka2_1:1,P00552,0.145115,NO,220,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.787,-3.529,2.742,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.520039,0.00158066,0.145115 kka2_1:1_S105N,kka2_1:1_105,Kka2,kka2_1:1,P00552,0.145121,NO,105,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.945,-3.821,1.876,,0.056,S,B,0.27,-1.04,3.442,,65.53,PPB,-2.17033,0.520039,0.00847233,0.145121 Ubiquitin_G10K,Ubiquitin_10,Uba1,Ubiquitin,P0CG48,0.145161,NO,10,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.396,-3.486,2.09,5.29806,0.115,S,l,,0.2,,,,POB,-1.38633,0.205827,0.000748953,0.145161 kka2_1:2_D101E,kka2_1:2_101,Kka2,kka2_1:2,P00552,0.145171,NO,101,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.028,-3.074,2.046,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.295029,0.00423361,0.145171 beta-lactamase_L247H,beta-lactamase_247,TEM-1,beta-lactamase,P62593,0.145194,NO,247,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.48,-4.987,3.507,5.28771,0.007,E,B,2.89,-0.72,2.951,,63.99,HHO,-1.79833,0.221079,0.00611275,0.145194 kka2_1:1_D62F,kka2_1:1_62,Kka2,kka2_1:1,P00552,0.1452,NO,62,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.591,-4.401,2.81,,0.262,H,A,0.75,0.08,10.048,10.048,64.39,PAA,-1.77833,0.520039,0.00744243,0.1452 beta-lactamase_2500_S241L,beta-lactamase_2500_241,TEM-1,beta-lactamase_2500,P62593,0.145216,NO,241,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.361275,0.00452736,0.145216 beta-lactamase_V257G,beta-lactamase_257,TEM-1,beta-lactamase,P62593,0.14525,NO,257,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.533,-3.573,2.04,5.31999,,E,B,0.96,-0.7,1.463,,58.74,HHH,-1.70967,0.221079,0.00756629,0.14525 kka2_1:2_L260H,kka2_1:2_260,Kka2,kka2_1:2,P00552,0.145452,NO,260,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.741,-4.933,4.192,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.295029,0.0233782,0.145452 kka2_1:4_Y244E,kka2_1:4_244,Kka2,kka2_1:4,P00552,0.145487,NO,244,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-0.775,-3.693,2.918,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.168804,0.00453187,0.145487 beta-lactamase_2500_E35T,beta-lactamase_2500_35,TEM-1,beta-lactamase_2500,P62593,0.145537,NO,35,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-0.869,-3.447,2.578,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.361275,0.00174441,0.145537 beta-lactamase_2500_D177E,beta-lactamase_2500_177,TEM-1,beta-lactamase_2500,P62593,0.14554,NO,177,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.967,-2.98,2.013,,0.006,T,L,0.75,-1.02,4.131,,64.69,BAP,-0.873667,0.361275,0.000864022,0.14554 beta-lactamase_A230H,beta-lactamase_230,TEM-1,beta-lactamase,P62593,0.145549,NO,230,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.154,-4.737,3.583,4.54336,0.01,E,B,0.75,-1.17,1.97,,50,HHA,-1.079,0.221079,0.00516841,0.145549 beta-lactamase_T261D,beta-lactamase_261,TEM-1,beta-lactamase,P62593,0.145549,NO,261,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.88,-4.081,1.201,5.65483,0.014,E,B,0.53,-0.39,2.449,,77.62,HPP,-1.771,0.221079,0.0123091,0.145549 beta-lactamase_39_I280R,beta-lactamase_39_280,TEM-1,beta-lactamase_39,P62593,0.145558,NO,280,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.0495842,0.0530888,0.145558 beta-lactamase_2500_I258W,beta-lactamase_2500_258,TEM-1,beta-lactamase_2500,P62593,0.145681,NO,258,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.361275,0.007931,0.145681 PSD95pdz3_A375K,PSD95pdz3_375,PSD95pdz3,PSD95pdz3,P31016,0.145758,NO,375,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.307,-3.139,1.832,5.05512,,,,,13.888,,,,PHH,-1.43767,0.0758425,0.000356809,0.145758 kka2_1:2_V185N,kka2_1:2_185,Kka2,kka2_1:2,P00552,0.1458,NO,185,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.045,-4.197,3.152,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.295029,0.00367031,0.1458 kka2_1:1_L103Q,kka2_1:1_103,Kka2,kka2_1:1,P00552,0.145865,NO,103,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-2.362,-4.06,1.698,,0.394,T,A,0.55,-0.99,4.121,,63.64,HHP,-1.534,0.520039,0.00574792,0.145865 beta-lactamase_39_I245D,beta-lactamase_39_245,TEM-1,beta-lactamase_39,P62593,0.145893,NO,245,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.0495842,0.00391032,0.145893 beta-lactamase_2500_E35L,beta-lactamase_2500_35,TEM-1,beta-lactamase_2500,P62593,0.145948,NO,35,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-0.869,-3.632,2.763,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.361275,0.00174441,0.145948 kka2_1:8_N195A,kka2_1:8_195,Kka2,kka2_1:8,P00552,0.145985,NO,195,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-0.836,-3.354,2.518,,0.037,G,A,0.43,-1.36,1.108,,48.11,OPH,-1.26567,0.100394,0.00276134,0.145985 kka2_1:8_N195A,kka2_1:8_195,Kka2,kka2_1:8,P00552,0.145985,NO,195,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-0.836,-3.354,2.518,,0.037,G,A,0.43,-1.36,1.108,,48.11,OPH,-1.26567,0.100394,0.00276134,0.145985 beta-lactamase_156_G249I,beta-lactamase_156_249,TEM-1,beta-lactamase_156,P62593,0.146058,NO,249,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.111618,0.00220169,0.146058 kka2_1:2_V49F,kka2_1:2_49,Kka2,kka2_1:2,P00552,0.14617,NO,49,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.614,-3.894,2.28,,,E,B,0.44,-0.77,1.233,,64.39,HHB,-1.3,0.295029,0.00615685,0.14617 beta-lactamase_2500_L137E,beta-lactamase_2500_137,TEM-1,beta-lactamase_2500,P62593,0.146171,NO,137,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.03,-3.919,2.889,,,H,A,0.55,-0.38,0.769,,42.31,HHP,-1.58933,0.361275,0.00278599,0.146171 beta-lactamase_W227L,beta-lactamase_227,TEM-1,beta-lactamase,P62593,0.14619,NO,227,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-0.982,-3.387,2.405,4.86393,0.272,,B,0.99,-0.29,1.37,,74.48,OHH,-1.595,0.221079,0.00226019,0.14619 kka2_1:1_A222P,kka2_1:1_222,Kka2,kka2_1:1,P00552,0.146285,NO,222,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.725,-3.683,2.958,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.520039,0.00207657,0.146285 beta-lactamase_39_T179R,beta-lactamase_39_179,TEM-1,beta-lactamase_39,P62593,0.146432,NO,179,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.085,-3.749,2.664,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.0495842,0.00226045,0.146432 beta-lactamase_2500_V42D,beta-lactamase_2500_42,TEM-1,beta-lactamase_2500,P62593,0.146434,NO,42,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.564,-4.059,2.495,,0.017,E,B,0.44,-0.51,1.86,,63.99,BHO,-1.042,0.361275,0.00404515,0.146434 kka2_1:2_H188F,kka2_1:2_188,Kka2,kka2_1:2,P00552,0.146487,NO,188,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-0.913,-3.931,3.018,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.295029,0.00273139,0.146487 kka2_1:2_Q27W,kka2_1:2_27,Kka2,kka2_1:2,P00552,0.146507,NO,27,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-1.659,-5.449,3.79,,0.608,.,A,0.64,0.71,0.521,,65.53,PPP,-1.90733,0.295029,0.00595365,0.146507 kka2_1:1_E199P,kka2_1:1_199,Kka2,kka2_1:1,P00552,0.146535,NO,199,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.234,-4.043,1.809,,0.508,E,B,1.04,-0.43,3.012,,65.53,HAP,-2.133,0.520039,0.00854122,0.146535 beta-lactamase_2500_G243N,beta-lactamase_2500_243,TEM-1,beta-lactamase_2500,P62593,0.146692,NO,243,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.361275,0.00464034,0.146692 kka2_1:4_D220W,kka2_1:4_220,Kka2,kka2_1:4,P00552,0.146811,NO,220,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.787,-5.574,4.787,,,H,A,0.75,-1.14,1.237,,46.59,PAH,-1.152,0.168804,0.00158066,0.146811 kka2_1:1_T225R,kka2_1:1_225,Kka2,kka2_1:1,P00552,0.146826,NO,225,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.393,-4.06,1.667,,0.036,H,A,0.22,-1.22,4.554,,63.64,HPB,-1.58733,0.520039,0.0113598,0.146826 beta-lactamase_156_K71W,beta-lactamase_156_71,TEM-1,beta-lactamase_156,P62593,0.146833,NO,71,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-0.8,-5.322,4.522,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.111618,0.00103192,0.146833 kka2_1:4_A222P,kka2_1:4_222,Kka2,kka2_1:4,P00552,0.146887,NO,222,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.725,-3.683,2.958,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.168804,0.00207657,0.146887 kka2_1:4_A191Q,kka2_1:4_191,Kka2,kka2_1:4,P00552,0.146896,NO,191,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.831,-3.962,3.131,,,.,b,0.46,-0.94,2.046,,50,AHO,-0.868667,0.168804,0.00338807,0.146896 kka2_1:1_L260H,kka2_1:1_260,Kka2,kka2_1:1,P00552,0.146919,NO,260,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.741,-4.933,4.192,,0.022,H,A,0.55,-0.52,,,,HHA,-0.845667,0.520039,0.0233782,0.146919 kka2_1:2_R258F,kka2_1:2_258,Kka2,kka2_1:2,P00552,0.146949,NO,258,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.626,-4.327,2.701,,0.316,H,A,1.2,-0.85,7.485,7.485,53.03,HBH,-1.25933,0.295029,0.00983174,0.146949 kka2_1:1_C77Y,kka2_1:1_77,Kka2,kka2_1:1,P00552,0.146954,NO,77,C,Y,CY,Special,Hydrophobic,5.07,5.66,0.59,194,121,181,60,108.5,193.6,85.1,-1.477,-4.33,2.853,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.520039,0.00441216,0.146954 beta-lactamase_2500_I280Q,beta-lactamase_2500_280,TEM-1,beta-lactamase_2500,P62593,0.147024,NO,280,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.361275,0.0530888,0.147024 beta-lactamase_625_I45D,beta-lactamase_625_45,TEM-1,beta-lactamase_625,P62593,0.147042,NO,45,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-2.421,-3.902,1.481,,,E,B,0.48,-0.3,3.642,,77.62,HHA,-2.30267,0.213352,0.00452842,0.147042 beta-lactamase_2500_S128F,beta-lactamase_2500_128,TEM-1,beta-lactamase_2500,P62593,0.147137,NO,128,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-0.84,-4.067,3.227,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.361275,0.00071483,0.147137 beta-lactamase_625_D155Y,beta-lactamase_625_155,TEM-1,beta-lactamase_625,P62593,0.147138,NO,155,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.889,-4.387,3.498,,0.049,,B,0.75,-0.9,4.922,,64.69,OAB,-1.62267,0.213352,0.00135315,0.147138 kka2_1:4_Y218T,kka2_1:4_218,Kka2,kka2_1:4,P00552,0.147147,NO,218,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-1.438,-3.77,2.332,,0.122,H,A,0.21,-0.69,1.022,,56.06,BHP,-1.17533,0.168804,0.0126098,0.147147 kka2_1:2_P194F,kka2_1:2_194,Kka2,kka2_1:2,P00552,0.147158,NO,194,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.846,-4.517,3.671,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.295029,0.00314194,0.147158 beta-lactamase_2500_V117D,beta-lactamase_2500_117,TEM-1,beta-lactamase_2500,P62593,0.147192,NO,117,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.53,-4.116,2.586,,,H,A,0.44,-0.34,1.23,,65.03,PHB,-1.741,0.361275,0.00467906,0.147192 beta-lactamase_N130E,beta-lactamase_130,TEM-1,beta-lactamase,P62593,0.147192,NO,130,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-0.798,-3.215,2.417,5.26686,0.069,H,A,1.08,-0.74,,,,APP,-0.980667,0.221079,0.000683376,0.147192 beta-lactamase_156_K232E,beta-lactamase_156_232,TEM-1,beta-lactamase_156,P62593,0.147327,NO,232,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.012,-3.087,2.075,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.111618,0.00313441,0.147327 kka2_1:4_L193W,kka2_1:4_193,Kka2,kka2_1:4,P00552,0.147332,NO,193,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.983,-5.198,4.215,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.168804,0.00480179,0.147332 beta-lactamase_V257H,beta-lactamase_257,TEM-1,beta-lactamase,P62593,0.147339,NO,257,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.533,-4.969,3.436,5.31999,,E,B,0.96,-0.7,1.463,,58.74,HHH,-1.70967,0.221079,0.00756629,0.147339 kka2_1:4_L232T,kka2_1:4_232,Kka2,kka2_1:4,P00552,0.14741,NO,232,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.514,-3.677,2.163,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.168804,0.00800103,0.14741 gb1_A252K,gb1_252,gb1,gb1,P06654,0.147441,NO,252,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.175,-3.192,2.017,,,,,,,,,,PHA,-1.55967,0.177985,0.00125598,0.147441 gb1_A260H,gb1_260,gb1,gb1,P06654,0.147441,NO,260,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.486,-4.652,3.166,,,,,,,0.173,,9.6,HHP,-1.70967,0.177985,0.0055808,0.147441 gb1_A260Q,gb1_260,gb1,gb1,P06654,0.147441,NO,260,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.486,-3.871,2.385,,,,,,,0.173,,9.6,HHP,-1.70967,0.177985,0.0055808,0.147441 gb1_E253C,gb1_253,gb1,gb1,P06654,0.147441,NO,253,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.71,-4.73,3.02,,,,,,,0.529,,11.83,HAB,-1.54433,0.177985,0.00141452,0.147441 gb1_F256E,gb1_256,gb1,gb1,P06654,0.147441,NO,256,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.241,-3.667,2.426,,,,,,,,,,HHB,-2.04767,0.177985,0.00435993,0.147441 gb1_F256R,gb1_256,gb1,gb1,P06654,0.147441,NO,256,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.241,-3.935,2.694,,,,,,,,,,HHB,-2.04767,0.177985,0.00435993,0.147441 gb1_F278G,gb1_278,gb1,gb1,P06654,0.147441,NO,278,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.418,-3.354,1.936,,,,,,,3.233,,35.71,PHP,-1.503,0.177985,0.00295699,0.147441 gb1_G267D,gb1_267,gb1,gb1,P06654,0.147441,NO,267,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.676,-3.624,1.948,,,,,,,1.361,,12.72,AOA,-1.61833,0.177985,0.00264655,0.147441 gb1_G267N,gb1_267,gb1,gb1,P06654,0.147441,NO,267,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.676,-3.691,2.015,,,,,,,1.361,,12.72,AOA,-1.61833,0.177985,0.00264655,0.147441 gb1_K254D,gb1_254,gb1,gb1,P06654,0.147441,NO,254,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.748,-2.98,1.232,,,,,,,1.793,,37.28,ABH,-2.195,0.177985,0.00622711,0.147441 gb1_K254E,gb1_254,gb1,gb1,P06654,0.147441,NO,254,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.748,-1.719,-0.029,,,,,,,1.793,,37.28,ABH,-2.195,0.177985,0.00622711,0.147441 gb1_K257W,gb1_257,gb1,gb1,P06654,0.147441,NO,257,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.775,-5.13,3.355,,,,,,,0.896,,37.28,HBP,-1.70367,0.177985,0.00640304,0.147441 gb1_V280R,gb1_280,gb1,gb1,P06654,0.147441,NO,280,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.764,-3.78,2.016,,,,,,,0.874,,35.71,PHP,-1.63733,0.177985,0.00321577,0.147441 gb1_W269C,gb1_269,gb1,gb1,P06654,0.147441,NO,269,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-1.198,-4.639,3.441,,,,,,,,,,AHP,-2.08867,0.177985,0.00270706,0.147441 gb1_W269G,gb1_269,gb1,gb1,P06654,0.147441,NO,269,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-1.198,-3.135,1.937,,,,,,,,,,AHP,-2.08867,0.177985,0.00270706,0.147441 gb1_W269R,gb1_269,gb1,gb1,P06654,0.147441,NO,269,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-1.198,-3.935,2.737,,,,,,,,,,AHP,-2.08867,0.177985,0.00270706,0.147441 kka2_1:1_K138N,kka2_1:1_138,Kka2,kka2_1:1,P00552,0.147504,NO,138,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-2.5,-3.757,1.257,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.520039,0.00628542,0.147504 beta-lactamase_625_L146R,beta-lactamase_625_146,TEM-1,beta-lactamase_625,P62593,0.147505,NO,146,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.462,-4.192,2.73,,0.007,H,A,0.55,-0.56,2.16,,64.69,AHP,-1.656,0.213352,0.00474542,0.147505 beta-lactamase_2500_N130Y,beta-lactamase_2500_130,TEM-1,beta-lactamase_2500,P62593,0.147527,NO,130,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-0.798,-4.162,3.364,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.361275,0.000683376,0.147527 beta-lactamase_2500_I245E,beta-lactamase_2500_245,TEM-1,beta-lactamase_2500,P62593,0.147561,NO,245,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.361275,0.00391032,0.147561 beta-lactamase_625_I280P,beta-lactamase_625_280,TEM-1,beta-lactamase_625,P62593,0.147589,NO,280,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.213352,0.0530888,0.147589 beta-lactamase_G234N,beta-lactamase_234,TEM-1,beta-lactamase,P62593,0.147618,NO,234,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.62,-3.448,2.828,4.24221,0.023,E,B,0.46,-0.86,,,,POH,-1.25733,0.221079,0.000889577,0.147618 kka2_1:1_P179M,kka2_1:1_179,Kka2,kka2_1:1,P00552,0.147646,NO,179,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.974,-4.581,3.607,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.520039,0.00298346,0.147646 kka2_1:8_I141E,kka2_1:8_141,Kka2,kka2_1:8,P00552,0.147676,NO,141,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.495,-3.998,2.503,,0.068,H,A,1.52,-0.01,2.144,,92.05,BHA,-1.689,0.100394,0.00744745,0.147676 kka2_1:8_I141E,kka2_1:8_141,Kka2,kka2_1:8,P00552,0.147676,NO,141,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.495,-3.998,2.503,,0.068,H,A,1.52,-0.01,2.144,,92.05,BHA,-1.689,0.100394,0.00744745,0.147676 kka2_1:1_A222F,kka2_1:1_222,Kka2,kka2_1:1,P00552,0.147708,NO,222,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.725,-4.095,3.37,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.520039,0.00207657,0.147708 beta-lactamase_156_K232P,beta-lactamase_156_232,TEM-1,beta-lactamase_156,P62593,0.147747,NO,232,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.012,-3.752,2.74,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.111618,0.00313441,0.147747 beta-lactamase_2500_G243T,beta-lactamase_2500_243,TEM-1,beta-lactamase_2500,P62593,0.14781,NO,243,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.361275,0.00464034,0.14781 beta-lactamase_625_F64R,beta-lactamase_625_64,TEM-1,beta-lactamase_625,P62593,0.147867,NO,64,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-0.841,-4.158,3.317,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.213352,0.000947691,0.147867 kka2_1:1_F240Y,kka2_1:1_240,Kka2,kka2_1:1,P00552,0.147915,NO,240,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-0.911,-3.189,2.278,,,H,A,1.62,-1.21,5.798,,50.38,BHH,-1.67267,0.520039,0.00552543,0.147915 kka2_1:4_H135S,kka2_1:4_135,Kka2,kka2_1:4,P00552,0.147928,NO,135,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-1.331,-3.439,2.108,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.168804,0.00532566,0.147928 beta-lactamase_2500_L150E,beta-lactamase_2500_150,TEM-1,beta-lactamase_2500,P62593,0.147991,NO,150,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.326,-3.822,2.496,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.361275,0.00463171,0.147991 kka2_1:2_V80Q,kka2_1:2_80,Kka2,kka2_1:2,P00552,0.148005,NO,80,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.144,-4.244,3.1,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.295029,0.00488211,0.148005 beta-lactamase_Y95K,beta-lactamase_95,TEM-1,beta-lactamase,P62593,0.148026,NO,95,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-1.715,-3.936,2.221,5.67068,0.122,,b,0.96,-0.37,2.341,,77.62,BHP,-2.16167,0.221079,0.00479449,0.148026 kka2_1:1_V185K,kka2_1:1_185,Kka2,kka2_1:1,P00552,0.148036,NO,185,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.045,-3.785,2.74,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.520039,0.00367031,0.148036 kka2_1:2_M116S,kka2_1:2_116,Kka2,kka2_1:2,P00552,0.148059,NO,116,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-2.482,-3.643,1.161,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.295029,0.00745147,0.148059 beta-lactamase_2500_N134L,beta-lactamase_2500_134,TEM-1,beta-lactamase_2500,P62593,0.148095,NO,134,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-0.879,-3.581,2.702,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.361275,0.000644786,0.148095 beta-lactamase_0_V117M,beta-lactamase_0_117,TEM-1,beta-lactamase_0,P62593,0.148199,NO,117,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.53,-3.063,1.533,,,H,A,0.44,-0.34,1.16,,65.03,PHB,-1.741,0.0500837,0.00467906,0.148199 beta-lactamase_156_M66R,beta-lactamase_156_66,TEM-1,beta-lactamase_156,P62593,0.148228,NO,66,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.362,-3.923,2.561,,0.013,,A,0.55,-0.7,1.94,,73.08,OHH,-1.49567,0.111618,0.00412876,0.148228 kka2_1:2_D227I,kka2_1:2_227,Kka2,kka2_1:2,P00552,0.148329,NO,227,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.758,-3.917,2.159,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.295029,0.00745029,0.148329 kka2_1:8_Y257E,kka2_1:8_257,Kka2,kka2_1:8,P00552,0.148337,NO,257,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-1.064,-3.82,2.756,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.100394,0.0148191,0.148337 kka2_1:8_Y257E,kka2_1:8_257,Kka2,kka2_1:8,P00552,0.148337,NO,257,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-1.064,-3.82,2.756,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.100394,0.0148191,0.148337 kka2_1:8_Y257I,kka2_1:8_257,Kka2,kka2_1:8,P00552,0.148337,NO,257,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-1.064,-3.568,2.504,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.100394,0.0148191,0.148337 kka2_1:8_Y257I,kka2_1:8_257,Kka2,kka2_1:8,P00552,0.148337,NO,257,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-1.064,-3.568,2.504,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.100394,0.0148191,0.148337 beta-lactamase_G248M,beta-lactamase_248,TEM-1,beta-lactamase,P62593,0.148342,NO,248,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.794,-4.674,2.88,4.69798,,E,b,0.23,-0.43,1.782,,61.19,HOO,-1.52867,0.221079,0.00428493,0.148342 kka2_1:1_M116E,kka2_1:1_116,Kka2,kka2_1:1,P00552,0.148464,NO,116,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-2.482,-3.963,1.481,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.520039,0.00745147,0.148464 beta-lactamase_2500_I261D,beta-lactamase_2500_261,TEM-1,beta-lactamase_2500,P62593,0.148533,NO,261,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.361275,0.0123091,0.148533 kka2_1:2_H188K,kka2_1:2_188,Kka2,kka2_1:2,P00552,0.148644,NO,188,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-0.913,-3.453,2.54,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.295029,0.00273139,0.148644 beta-lactamase_156_I280Q,beta-lactamase_156_280,TEM-1,beta-lactamase_156,P62593,0.148662,NO,280,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.111618,0.0530888,0.148662 beta-lactamase_2500_D155P,beta-lactamase_2500_155,TEM-1,beta-lactamase_2500,P62593,0.148675,NO,155,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.889,-3.725,2.836,,0.049,,B,0.75,-0.9,2.386,,64.69,OAB,-1.62267,0.361275,0.00135315,0.148675 kka2_1:2_G30Q,kka2_1:2_30,Kka2,kka2_1:2,P00552,0.148684,NO,30,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.596,-4.153,3.557,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.295029,0.00159208,0.148684 kka2_1:1_V198W,kka2_1:1_198,Kka2,kka2_1:1,P00552,0.148701,NO,198,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.719,-5.441,3.722,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.520039,0.00835002,0.148701 beta-lactamase_2500_L160Y,beta-lactamase_2500_160,TEM-1,beta-lactamase_2500,P62593,0.148707,NO,160,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.977,-3.98,3.003,,0.022,,B,0.55,-0.6,0.895,,44.41,BHA,-0.936,0.361275,0.00193775,0.148707 beta-lactamase_2500_R257F,beta-lactamase_2500_257,TEM-1,beta-lactamase_2500,P62593,0.14873,NO,257,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.361275,0.00756629,0.14873 kka2_1:2_Q219F,kka2_1:2_219,Kka2,kka2_1:2,P00552,0.148764,NO,219,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-0.93,-4.344,3.414,,0.088,H,A,0.4,-0.85,1.917,,50,HPA,-1.05167,0.295029,0.00237913,0.148764 beta-lactamase_625_T158L,beta-lactamase_625_158,TEM-1,beta-lactamase_625,P62593,0.14878,NO,158,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.116,-3.303,2.187,,0.036,,B,0.22,-0.85,3.771,,69.58,HPB,-1.269,0.213352,0.00341825,0.14878 kka2_1:1_G99Q,kka2_1:1_99,Kka2,kka2_1:1,P00552,0.148795,NO,99,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.596,-4.153,3.557,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.520039,0.00186055,0.148795 kka2_1:4_Y218K,kka2_1:4_218,Kka2,kka2_1:4,P00552,0.148797,NO,218,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-1.438,-3.819,2.381,,0.122,H,A,0.21,-0.69,1.022,,56.06,BHP,-1.17533,0.168804,0.0126098,0.148797 beta-lactamase_625_M209R,beta-lactamase_625_209,TEM-1,beta-lactamase_625,P62593,0.148827,NO,209,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.442,-3.939,2.497,,,H,A,0.55,-0.97,1.167,,64.69,HHA,-1.52633,0.213352,0.00625021,0.148827 beta-lactamase_625_G234L,beta-lactamase_625_234,TEM-1,beta-lactamase_625,P62593,0.148886,NO,234,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.62,-3.808,3.188,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.213352,0.000889577,0.148886 kka2_1:1_N195Q,kka2_1:1_195,Kka2,kka2_1:1,P00552,0.148898,NO,195,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-0.836,-3.726,2.89,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.520039,0.00276134,0.148898 beta-lactamase_2500_L205C,beta-lactamase_2500_205,TEM-1,beta-lactamase_2500,P62593,0.148901,NO,205,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.922,-4.692,3.77,,,H,A,0.55,-0.46,0.831,,42.31,PHH,-1.57767,0.361275,0.00255802,0.148901 beta-lactamase_2500_K71N,beta-lactamase_2500_71,TEM-1,beta-lactamase_2500,P62593,0.148951,NO,71,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-0.8,-3.448,2.648,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.361275,0.00103192,0.148951 kka2_1:1_F37H,kka2_1:1_37,Kka2,kka2_1:1,P00552,0.148976,NO,37,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.427,-2.73,1.303,,0.219,E,B,0.58,-0.25,18.64,18.64,64.39,HHB,-1.17733,0.520039,0.00586193,0.148976 beta-lactamase_625_I245R,beta-lactamase_625_245,TEM-1,beta-lactamase_625,P62593,0.148981,NO,245,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.213352,0.00391032,0.148981 beta-lactamase_2500_M209H,beta-lactamase_2500_209,TEM-1,beta-lactamase_2500,P62593,0.149039,NO,209,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.442,-4.813,3.371,,,H,A,0.55,-0.97,3.229,,64.69,HHA,-1.52633,0.361275,0.00625021,0.149039 beta-lactamase_625_C75P,beta-lactamase_625_75,TEM-1,beta-lactamase_625,P62593,0.149062,NO,75,C,P,CP,Special,Special,5.07,6.3,1.23,169,121,115,-6,108.5,112.7,4.2,-1.245,-4.012,2.767,,,H,A,0.46,-0.87,2.141,,50,HOO,-1.24333,0.213352,0.0034616,0.149062 kka2_1:2_D261C,kka2_1:2_261,Kka2,kka2_1:2,P00552,0.149076,NO,261,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.708,-5.115,4.407,,0.146,G,A,0.75,-0.33,,,,HAA,-0.759333,0.295029,0.0224846,0.149076 beta-lactamase_39_L248R,beta-lactamase_39_248,TEM-1,beta-lactamase_39,P62593,0.149097,NO,248,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.0495842,0.00428493,0.149097 beta-lactamase_T179G,beta-lactamase_179,TEM-1,beta-lactamase,P62593,0.149119,NO,179,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.085,-3.296,2.211,5.07116,,E,B,0.8,-1.38,1.859,,73.08,PPH,-1.557,0.221079,0.00226045,0.149119 beta-lactamase_0_C121G,beta-lactamase_0_121,TEM-1,beta-lactamase_0,P62593,0.149181,NO,121,C,G,CG,Special,Special,5.07,3.29388,-1.77612,159,121,75,-46,108.5,60.1,-48.4,-0.953,-3.581,2.628,,,H,A,0.46,-0.81,3.302,,63.29,HOP,-1.46767,0.0500837,0.000744322,0.149181 PSD95pdz3_G324V,PSD95pdz3_324,PSD95pdz3,PSD95pdz3,P31016,0.149186,NO,324,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.008,-3.435,2.427,4.98881,,,,,10.4525,,,,HOH,-1.293,0.0758425,0.00103462,0.149186 kka2_1:2_A78F,kka2_1:2_78,Kka2,kka2_1:2,P00552,0.149196,NO,78,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.744,-4.44,2.696,,0.078,.,B,0.46,-0.53,0.206,,56.06,OHH,-1.863,0.295029,0.00457299,0.149196 beta-lactamase_2500_W227E,beta-lactamase_2500_227,TEM-1,beta-lactamase_2500,P62593,0.149327,NO,227,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-0.982,-3.914,2.932,,0.272,,B,0.47,-0.29,1.37,,74.48,OHH,-1.595,0.361275,0.00226019,0.149327 kka2_1:4_W236T,kka2_1:4_236,Kka2,kka2_1:4,P00552,0.14934,NO,236,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-1.363,-3.713,2.35,,0.303,H,A,0.47,-0.76,2.277,,48.48,AHH,-1.81267,0.168804,0.0088796,0.14934 beta-lactamase_2500_I261S,beta-lactamase_2500_261,TEM-1,beta-lactamase_2500,P62593,0.149355,NO,261,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.361275,0.0123091,0.149355 kka2_1:1_R253Q,kka2_1:1_253,Kka2,kka2_1:1,P00552,0.149371,NO,253,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.356,-3.67,2.314,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.520039,0.0144195,0.149371 beta-lactamase_39_A132H,beta-lactamase_39_132,TEM-1,beta-lactamase_39,P62593,0.149399,NO,132,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.9,-4.724,3.824,,,H,A,0.46,-0.93,8.408,,64.69,PHH,-1.138,0.0495842,0.000962524,0.149399 kka2_1:2_G95F,kka2_1:2_95,Kka2,kka2_1:2,P00552,0.149404,NO,95,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-2.403,-4.378,1.975,,0.126,E,B,0.29,-0.74,0.359,,71.59,HOA,-2.198,0.295029,0.00743616,0.149404 kka2_1:2_G189K,kka2_1:2_189,Kka2,kka2_1:2,P00552,0.149424,NO,189,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.596,-3.71,3.114,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.295029,0.00253688,0.149424 beta-lactamase_G76N,beta-lactamase_76,TEM-1,beta-lactamase,P62593,0.149428,NO,76,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.189,-3.655,2.466,4.73862,,H,A,2.05,-0.67,3.059,,67.83,OOH,-1.22267,0.221079,0.00476637,0.149428 beta-lactamase_2500_S128A,beta-lactamase_2500_128,TEM-1,beta-lactamase_2500,P62593,0.14944,NO,128,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-0.84,-2.628,1.788,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.361275,0.00071483,0.14944 beta-lactamase_625_E35Y,beta-lactamase_625_35,TEM-1,beta-lactamase_625,P62593,0.14946,NO,35,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-0.869,-4.211,3.342,,0.15,H,A,1.04,0.21,0.664,,46.85,HAA,-1.88667,0.213352,0.00174441,0.14946 kka2_1:2_I141H,kka2_1:2_141,Kka2,kka2_1:2,P00552,0.149473,NO,141,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.495,-5.058,3.563,,0.068,H,A,0.48,-0.01,0.819,,92.05,BHA,-1.689,0.295029,0.00744745,0.149473 beta-lactamase_156_R257D,beta-lactamase_156_257,TEM-1,beta-lactamase_156,P62593,0.149564,NO,257,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.111618,0.00756629,0.149564 kka2_1:2_G213T,kka2_1:2_213,Kka2,kka2_1:2,P00552,0.149567,NO,213,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.596,-3.675,3.079,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.295029,0.00187654,0.149567 beta-lactamase_2500_A132F,beta-lactamase_2500_132,TEM-1,beta-lactamase_2500,P62593,0.149643,NO,132,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.9,-4.091,3.191,,,H,A,0.46,-0.93,8.408,,64.69,PHH,-1.138,0.361275,0.000962524,0.149643 kka2_1:4_F264D,kka2_1:4_264,Kka2,kka2_1:4,P00552,0.149671,NO,264,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.02,-4.038,3.018,,0.296,,?,1.62,0.02,1.93,,71.59,HHO,-0.9655,0.168804,,0.149671 beta-lactamase_156_V42P,beta-lactamase_156_42,TEM-1,beta-lactamase_156,P62593,0.149677,NO,42,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.564,-4.095,2.531,,0.017,E,B,0.44,-0.51,2.576,,63.99,BHO,-1.042,0.111618,0.00404515,0.149677 kka2_1:2_T187H,kka2_1:2_187,Kka2,kka2_1:2,P00552,0.149681,NO,187,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.273,-4.848,3.575,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.295029,0.00693073,0.149681 beta-lactamase_156_K71P,beta-lactamase_156_71,TEM-1,beta-lactamase_156,P62593,0.149722,NO,71,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-0.8,-3.655,2.855,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.111618,0.00103192,0.149722 beta-lactamase_S104E,beta-lactamase_104,TEM-1,beta-lactamase,P62593,0.149755,NO,104,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.015,-3.366,2.351,4.92365,0.04,,b,0.82,0.57,4.02,,63.29,HPO,-1.05267,0.221079,0.00218083,0.149755 beta-lactamase_39_G43K,beta-lactamase_39_43,TEM-1,beta-lactamase_39,P62593,0.149818,NO,43,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.62,-3.682,3.062,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.0495842,0.00120151,0.149818 kka2_1:4_N195P,kka2_1:4_195,Kka2,kka2_1:4,P00552,0.149853,NO,195,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-0.836,-3.906,3.07,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.168804,0.00276134,0.149853 kka2_1:8_G213W,kka2_1:8_213,Kka2,kka2_1:8,P00552,0.149872,NO,213,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.596,-5.126,4.53,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.100394,0.00187654,0.149872 kka2_1:8_G213W,kka2_1:8_213,Kka2,kka2_1:8,P00552,0.149872,NO,213,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.596,-5.126,4.53,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.100394,0.00187654,0.149872 beta-lactamase_2500_L74N,beta-lactamase_2500_74,TEM-1,beta-lactamase_2500,P62593,0.149898,NO,74,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.296,-4.114,2.818,,,H,A,0.55,-0.91,0.746,,50,HHO,-1.34933,0.361275,0.00493255,0.149898 beta-lactamase_2500_E164M,beta-lactamase_2500_164,TEM-1,beta-lactamase_2500,P62593,0.149906,NO,164,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-0.948,-4.749,3.801,,0.011,T,B,1.04,-0.4,0.352,,64.69,HAO,-1.388,0.361275,0.00137286,0.149906 beta-lactamase_2500_L74P,beta-lactamase_2500_74,TEM-1,beta-lactamase_2500,P62593,0.149918,NO,74,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.296,-4.001,2.705,,,H,A,0.55,-0.91,0.746,,50,HHO,-1.34933,0.361275,0.00493255,0.149918 beta-lactamase_625_W288S,beta-lactamase_625_288,TEM-1,beta-lactamase_625,P62593,0.149973,NO,288,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,,,,,,,,,,,,,BHO,,0.213352,,0.149973 kka2_1:1_A176I,kka2_1:1_176,Kka2,kka2_1:1,P00552,0.149982,NO,176,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.621,-4.019,2.398,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.520039,0.0083587,0.149982 beta-lactamase_625_M66W,beta-lactamase_625_66,TEM-1,beta-lactamase_625,P62593,0.150064,NO,66,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.362,-5.087,3.725,,0.013,,A,0.55,-0.7,1.659,,73.08,OHH,-1.49567,0.213352,0.00412876,0.150064 beta-lactamase_156_T179F,beta-lactamase_156_179,TEM-1,beta-lactamase_156,P62593,0.15011,NO,179,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.085,-4.108,3.023,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.111618,0.00226045,0.15011 beta-lactamase_625_T158Q,beta-lactamase_625_158,TEM-1,beta-lactamase_625,P62593,0.150146,NO,158,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.116,-3.908,2.792,,0.036,,B,0.22,-0.85,3.771,,69.58,HPB,-1.269,0.213352,0.00341825,0.150146 kka2_1:4_V113W,kka2_1:4_113,Kka2,kka2_1:4,P00552,0.150183,NO,113,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.233,-5.432,4.199,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.168804,0.00650191,0.150183 kka2_1:1_R226I,kka2_1:1_226,Kka2,kka2_1:1,P00552,0.150226,NO,226,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.392,-4.182,2.79,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.520039,0.0108032,0.150226 beta-lactamase_39_P181E,beta-lactamase_39_181,TEM-1,beta-lactamase_39,P62593,0.150245,NO,181,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.813,-3.466,2.653,,,H,A,0.52,-1.14,1.946,,61.54,HOH,-1.795,0.0495842,0.000703122,0.150245 kka2_1:1_G210P,kka2_1:1_210,Kka2,kka2_1:1,P00552,0.150246,NO,210,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.095,-3.953,2.858,,0.103,T,A,0.29,-0.62,14.483,14.483,50,OOB,-0.966667,0.520039,0.00598378,0.150246 beta-lactamase_39_M66D,beta-lactamase_39_66,TEM-1,beta-lactamase_39,P62593,0.150271,NO,66,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.362,-4.069,2.707,,0.013,,A,0.55,-0.7,1.319,,73.08,OHH,-1.49567,0.0495842,0.00412876,0.150271 kka2_1:1_E231C,kka2_1:1_231,Kka2,kka2_1:1,P00552,0.150287,NO,231,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.002,-3.282,1.28,,0.503,H,A,1.04,-0.23,25.629,25.629,63.26,AAH,-2.06267,0.520039,0.00732383,0.150287 E1_Ubiquitin_H70Q,E1_Ubiquitin_70,Uba1,E1_Ubiquitin,P0CG63,0.150309,NO,70,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-1.36,,,,0.05,E,B,0.61,-0.97,,,93.18,HBH,-1.146,0.18783,0.00206914,0.150309 kka2_1:8_L232E,kka2_1:8_232,Kka2,kka2_1:8,P00552,0.15031,NO,232,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.514,-3.993,2.479,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.100394,0.00800103,0.15031 kka2_1:8_L232E,kka2_1:8_232,Kka2,kka2_1:8,P00552,0.15031,NO,232,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.514,-3.993,2.479,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.100394,0.00800103,0.15031 PSD95pdz3_I359N,PSD95pdz3_359,PSD95pdz3,PSD95pdz3,P31016,0.150432,NO,359,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.63,-3.805,2.175,5.35151,,,,,14.8012,,,,PHH,-1.58667,0.0758425,0.000580694,0.150432 kka2_1:1_G74T,kka2_1:1_74,Kka2,kka2_1:1,P00552,0.150461,NO,74,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.18,-3.624,2.444,,0.621,T,l,0.75,0.2,15.356,15.356,64.39,POH,-1.91667,0.520039,0.00587035,0.150461 kka2_1:1_D190K,kka2_1:1_190,Kka2,kka2_1:1,P00552,0.150499,NO,190,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.708,-3.485,2.777,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.520039,0.00247989,0.150499 beta-lactamase_625_I125W,beta-lactamase_625_125,TEM-1,beta-lactamase_625,P62593,0.15052,NO,125,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.441,-5.341,3.9,,,H,A,0.48,-0.7,2.034,,63.29,HHP,-1.248,0.213352,0.00383964,0.15052 beta-lactamase_2500_T179G,beta-lactamase_2500_179,TEM-1,beta-lactamase_2500,P62593,0.150525,NO,179,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.085,-3.296,2.211,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.361275,0.00226045,0.150525 kka2_1:4_L260K,kka2_1:4_260,Kka2,kka2_1:4,P00552,0.150533,NO,260,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.741,-3.71,2.969,,0.022,H,A,0.55,-0.52,,,,HHA,-0.845667,0.168804,0.0233782,0.150533 beta-lactamase_2500_L146H,beta-lactamase_2500_146,TEM-1,beta-lactamase_2500,P62593,0.150607,NO,146,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.462,-4.92,3.458,,0.007,H,A,0.55,-0.56,1.578,,64.69,AHP,-1.656,0.361275,0.00474542,0.150607 PSD95pdz3_G329Q,PSD95pdz3_329,PSD95pdz3,PSD95pdz3,P31016,0.150619,NO,329,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.008,-3.806,2.798,4.7671,,,,,19.7075,,,,HOO,-1.16033,0.0758425,0.000974577,0.150619 beta-lactamase_I275Q,beta-lactamase_275,TEM-1,beta-lactamase,P62593,0.150673,NO,275,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.397,-4.258,2.861,5.3999,0.015,H,A,1,-0.52,0.836,,62.59,PHH,-1.541,0.221079,0.0141984,0.150673 kka2_1:1_L241K,kka2_1:1_241,Kka2,kka2_1:1,P00552,0.150687,NO,241,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.158,-3.87,2.712,,0.08,H,A,0.55,-0.82,1.685,,63.26,HHH,-1.58533,0.520039,0.0117299,0.150687 beta-lactamase_625_V31N,beta-lactamase_625_31,TEM-1,beta-lactamase_625,P62593,0.150723,NO,31,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.822,-4.194,2.372,,,H,A,0.44,-0.46,2.576,,73.78,BHB,-2.03767,0.213352,0.00478065,0.150723 beta-lactamase_625_Y262K,beta-lactamase_625_262,TEM-1,beta-lactamase_625,P62593,0.150734,NO,262,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.213352,0.00853516,0.150734 kka2_1:2_E262H,kka2_1:2_262,Kka2,kka2_1:2,P00552,0.150742,NO,262,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-0.829,-4.282,3.453,,0.059,G,A,1.04,-0.18,2.383,,42.42,AAH,-0.816,0.295029,0.0191586,0.150742 beta-lactamase_T262P,beta-lactamase_262,TEM-1,beta-lactamase,P62593,0.150785,NO,262,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.332,-3.798,2.466,5.06002,0.108,E,B,0.3,-0.55,1.423,,67.83,PPO,-2.081,0.221079,0.00853516,0.150785 beta-lactamase_156_P181Q,beta-lactamase_156_181,TEM-1,beta-lactamase_156,P62593,0.150807,NO,181,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.813,-3.925,3.112,,,H,A,0.52,-1.14,1.078,,61.54,HOH,-1.795,0.111618,0.000703122,0.150807 beta-lactamase_I244E,beta-lactamase_244,TEM-1,beta-lactamase,P62593,0.150814,NO,244,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.555,-3.795,2.24,5.35885,,E,B,0.01,-0.84,0.379,,77.62,HHH,-1.385,0.221079,0.00605379,0.150814 beta-lactamase_625_D155Q,beta-lactamase_625_155,TEM-1,beta-lactamase_625,P62593,0.150832,NO,155,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.889,-3.667,2.778,,0.049,,B,0.75,-0.9,4.922,,64.69,OAB,-1.62267,0.213352,0.00135315,0.150832 kka2_1:2_A215L,kka2_1:2_215,Kka2,kka2_1:2,P00552,0.150848,NO,215,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.968,-3.296,2.328,,0.039,E,B,0.46,-0.59,2.137,,50.38,HHA,-1.00467,0.295029,0.00529129,0.150848 beta-lactamase_2500_M67Y,beta-lactamase_2500_67,TEM-1,beta-lactamase_2500,P62593,0.150854,NO,67,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-2.231,-4.282,2.051,,0.006,G,P,0.55,-0.81,2.653,,65.03,HHP,-1.502,0.361275,0.00409753,0.150854 beta-lactamase_2500_T178F,beta-lactamase_2500_178,TEM-1,beta-lactamase_2500,P62593,0.15087,NO,178,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-0.791,-4.067,3.276,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.361275,0.000684366,0.15087 beta-lactamase_625_D155W,beta-lactamase_625_155,TEM-1,beta-lactamase_625,P62593,0.150915,NO,155,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.889,-5.571,4.682,,0.049,,B,0.75,-0.9,4.922,,64.69,OAB,-1.62267,0.213352,0.00135315,0.150915 kka2_1:1_S40D,kka2_1:1_40,Kka2,kka2_1:1,P00552,0.150918,NO,40,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.645,-2.229,-0.416,,0.32,E,B,0.27,-0.9,25.997,25.997,71.59,HPH,-1.91567,0.520039,0.00693477,0.150918 beta-lactamase_156_T179K,beta-lactamase_156_179,TEM-1,beta-lactamase_156,P62593,0.150938,NO,179,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.085,-3.486,2.401,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.111618,0.00226045,0.150938 kka2_1:8_V75D,kka2_1:8_75,Kka2,kka2_1:8,P00552,0.150965,NO,75,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-2.06,-4.066,2.006,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.100394,0.00693733,0.150965 kka2_1:8_V75D,kka2_1:8_75,Kka2,kka2_1:8,P00552,0.150965,NO,75,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-2.06,-4.066,2.006,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.100394,0.00693733,0.150965 beta-lactamase_625_I125F,beta-lactamase_625_125,TEM-1,beta-lactamase_625,P62593,0.151003,NO,125,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.441,-3.841,2.4,,,H,A,0.48,-0.7,2.034,,63.29,HHP,-1.248,0.213352,0.00383964,0.151003 kka2_1:2_T187M,kka2_1:2_187,Kka2,kka2_1:2,P00552,0.151062,NO,187,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.273,-4.606,3.333,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.295029,0.00693073,0.151062 beta-lactamase_2500_E164I,beta-lactamase_2500_164,TEM-1,beta-lactamase_2500,P62593,0.151072,NO,164,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-0.948,-4.08,3.132,,0.011,T,B,1.04,-0.4,0.352,,64.69,HAO,-1.388,0.361275,0.00137286,0.151072 kka2_1:1_G233E,kka2_1:1_233,Kka2,kka2_1:1,P00552,0.151096,NO,233,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.748,-3.501,2.753,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.520039,0.00232366,0.151096 kka2_1:8_G233W,kka2_1:8_233,Kka2,kka2_1:8,P00552,0.151183,NO,233,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.748,-5.239,4.491,,0.172,,b,0.75,-0.27,1.134,,49.24,HOO,-1.72067,0.100394,0.00232366,0.151183 kka2_1:8_G233W,kka2_1:8_233,Kka2,kka2_1:8,P00552,0.151183,NO,233,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.748,-5.239,4.491,,0.172,,b,0.75,-0.27,1.134,,49.24,HOO,-1.72067,0.100394,0.00232366,0.151183 kka2_1:8_M116E,kka2_1:8_116,Kka2,kka2_1:8,P00552,0.151183,NO,116,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-2.482,-3.963,1.481,,,H,A,1.59,-0.88,4.659,,71.59,HHH,-1.63867,0.100394,0.00745147,0.151183 kka2_1:8_M116E,kka2_1:8_116,Kka2,kka2_1:8,P00552,0.151183,NO,116,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-2.482,-3.963,1.481,,,H,A,1.59,-0.88,4.659,,71.59,HHH,-1.63867,0.100394,0.00745147,0.151183 kka2_1:4_N195I,kka2_1:4_195,Kka2,kka2_1:4,P00552,0.151191,NO,195,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-0.836,-4.062,3.226,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.168804,0.00276134,0.151191 beta-lactamase_156_V259R,beta-lactamase_156_259,TEM-1,beta-lactamase_156,P62593,0.151207,NO,259,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.111618,0.0070773,0.151207 kka2_1:4_R217W,kka2_1:4_217,Kka2,kka2_1:4,P00552,0.151221,NO,217,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.158,-5.446,4.288,,0.252,T,A,1.2,-0.59,2.074,,52.27,ABH,-1.127,0.168804,0.0047191,0.151221 kka2_1:8_P194H,kka2_1:8_194,Kka2,kka2_1:8,P00552,0.151401,NO,194,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.846,-4.708,3.862,,0.308,G,A,0.52,-1.19,4.861,,53.03,HOP,-0.888333,0.100394,0.00314194,0.151401 kka2_1:8_P194H,kka2_1:8_194,Kka2,kka2_1:8,P00552,0.151401,NO,194,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.846,-4.708,3.862,,0.308,G,A,0.52,-1.19,4.861,,53.03,HOP,-0.888333,0.100394,0.00314194,0.151401 beta-lactamase_625_E62P,beta-lactamase_625_62,TEM-1,beta-lactamase_625,P62593,0.151402,NO,62,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.193,-3.775,2.582,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.213352,0.00264802,0.151402 kka2_1:2_G99M,kka2_1:2_99,Kka2,kka2_1:2,P00552,0.151489,NO,99,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.596,-4.958,4.362,,0.368,S,g,0.29,-0.87,,,,OOP,-1.63067,0.295029,0.00186055,0.151489 Pab1_N127E,Pab1_127,Pab1,Pab1,P04147,0.151497,NO,127,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-1.079,-3.032,1.953,,0.138,E,B,1.05,-0.51,,,,OPH,-1.13633,0.175299,0.000805159,0.151497 kka2_1:2_L193N,kka2_1:2_193,Kka2,kka2_1:2,P00552,0.151539,NO,193,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.983,-4.109,3.126,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.295029,0.00480179,0.151539 beta-lactamase_2500_G240M,beta-lactamase_2500_240,TEM-1,beta-lactamase_2500,P62593,0.151564,NO,240,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.361275,0.00591201,0.151564 beta-lactamase_625_W227T,beta-lactamase_625_227,TEM-1,beta-lactamase_625,P62593,0.15157,NO,227,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-0.982,-3.696,2.714,,0.272,,B,0.47,-0.29,2.533,,74.48,OHH,-1.595,0.213352,0.00226019,0.15157 beta-lactamase_2500_A185W,beta-lactamase_2500_185,TEM-1,beta-lactamase_2500,P62593,0.151606,NO,185,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.406,-5.387,3.981,,,H,A,0.46,-1.02,2.999,,65.03,HHP,-1.84033,0.361275,0.00467449,0.151606 beta-lactamase_D129E,beta-lactamase_129,TEM-1,beta-lactamase,P62593,0.15162,NO,129,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.816,-2.232,1.416,4.84204,,,B,1.33,-0.69,0.548,,34.97,PAP,-0.818,0.221079,0.00109178,0.15162 beta-lactamase_39_N134P,beta-lactamase_39_134,TEM-1,beta-lactamase_39,P62593,0.151645,NO,134,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-0.879,-3.877,2.998,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.0495842,0.000644786,0.151645 beta-lactamase_625_V259G,beta-lactamase_625_259,TEM-1,beta-lactamase_625,P62593,0.151653,NO,259,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.213352,0.0070773,0.151653 PSD95pdz3_G329A,PSD95pdz3_329,PSD95pdz3,PSD95pdz3,P31016,0.151678,NO,329,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.008,-2.534,1.526,4.7671,,,,,19.7075,,,,HOO,-1.16033,0.0758425,0.000974577,0.151678 beta-lactamase_39_G43E,beta-lactamase_39_43,TEM-1,beta-lactamase_39,P62593,0.15169,NO,43,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.62,-3.665,3.045,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.0495842,0.00120151,0.15169 kka2_1:4_L232N,kka2_1:4_232,Kka2,kka2_1:4,P00552,0.151858,NO,232,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.514,-4.176,2.662,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.168804,0.00800103,0.151858 beta-lactamase_F70D,beta-lactamase_70,TEM-1,beta-lactamase,P62593,0.151896,NO,70,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.169,-3.91,2.741,5.42055,,H,A,1.1,-1.34,1.14,,63.99,PHB,-0.980667,0.221079,0.00193499,0.151896 beta-lactamase_625_L192K,beta-lactamase_625_192,TEM-1,beta-lactamase_625,P62593,0.15193,NO,192,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.254,-3.803,2.549,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.213352,0.00558728,0.15193 beta-lactamase_625_P181H,beta-lactamase_625_181,TEM-1,beta-lactamase_625,P62593,0.151946,NO,181,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.813,-4.706,3.893,,,H,A,0.52,-1.14,1.797,,61.54,HOH,-1.795,0.213352,0.000703122,0.151946 beta-lactamase_156_C75Y,beta-lactamase_156_75,TEM-1,beta-lactamase_156,P62593,0.151947,NO,75,C,Y,CY,Special,Hydrophobic,5.07,5.66,0.59,194,121,181,60,108.5,193.6,85.1,-1.245,-4.265,3.02,,,H,A,0.46,-0.87,0.876,,50,HOO,-1.24333,0.111618,0.0034616,0.151947 beta-lactamase_156_L192R,beta-lactamase_156_192,TEM-1,beta-lactamase_156,P62593,0.15204,NO,192,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.254,-4.095,2.841,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.111618,0.00558728,0.15204 kka2_1:1_A229Y,kka2_1:1_229,Kka2,kka2_1:1,P00552,0.152111,NO,229,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.739,-4.342,2.603,,0.32,H,A,0.46,-0.7,6.549,,63.64,HHA,-1.851,0.520039,0.00942138,0.152111 kka2_1:2_L241E,kka2_1:2_241,Kka2,kka2_1:2,P00552,0.152149,NO,241,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.158,-4.005,2.847,,0.08,H,A,0.55,-0.82,1.598,,63.26,HHH,-1.58533,0.295029,0.0117299,0.152149 beta-lactamase_2500_I258P,beta-lactamase_2500_258,TEM-1,beta-lactamase_2500,P62593,0.152362,NO,258,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.361275,0.007931,0.152362 kka2_1:1_G233N,kka2_1:1_233,Kka2,kka2_1:1,P00552,0.152406,NO,233,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.748,-3.476,2.728,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.520039,0.00232366,0.152406 beta-lactamase_2500_T178P,beta-lactamase_2500_178,TEM-1,beta-lactamase_2500,P62593,0.152415,NO,178,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-0.791,-3.655,2.864,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.361275,0.000684366,0.152415 beta-lactamase_2500_I229E,beta-lactamase_2500_229,TEM-1,beta-lactamase_2500,P62593,0.152422,NO,229,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.267,-3.864,2.597,,0.083,E,B,0.48,-0.76,3.875,,50,HHH,-1.58767,0.361275,0.00477249,0.152422 beta-lactamase_625_G142L,beta-lactamase_625_142,TEM-1,beta-lactamase_625,P62593,0.152446,NO,142,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.707,-3.771,3.064,,0.034,,p,0.29,-0.64,1.35,,64.69,OOO,-0.834,0.213352,0.00060149,0.152446 kka2_1:4_D220E,kka2_1:4_220,Kka2,kka2_1:4,P00552,0.15245,NO,220,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.787,-2.878,2.091,,,H,A,0.75,-1.14,1.237,,46.59,PAH,-1.152,0.168804,0.00158066,0.15245 beta-lactamase_625_F149P,beta-lactamase_625_149,TEM-1,beta-lactamase_625,P62593,0.152469,NO,149,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.299,-4.282,2.983,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.213352,0.00418462,0.152469 beta-lactamase_2500_T178D,beta-lactamase_2500_178,TEM-1,beta-lactamase_2500,P62593,0.15247,NO,178,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-0.791,-3.469,2.678,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.361275,0.000684366,0.15247 kka2_1:2_H135C,kka2_1:2_135,Kka2,kka2_1:2,P00552,0.152476,NO,135,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-1.331,-5.106,3.775,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.295029,0.00532566,0.152476 kka2_1:4_L193N,kka2_1:4_193,Kka2,kka2_1:4,P00552,0.152557,NO,193,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.983,-4.109,3.126,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.168804,0.00480179,0.152557 beta-lactamase_2500_D155M,beta-lactamase_2500_155,TEM-1,beta-lactamase_2500,P62593,0.152639,NO,155,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.889,-4.929,4.04,,0.049,,B,0.75,-0.9,2.386,,64.69,OAB,-1.62267,0.361275,0.00135315,0.152639 beta-lactamase_R202P,beta-lactamase_202,TEM-1,beta-lactamase,P62593,0.152649,NO,202,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.292,-3.859,2.567,5.16273,0.188,H,A,0.68,0.62,1.918,,77.62,PBP,-1.54767,0.221079,0.00321899,0.152649 beta-lactamase_39_T179Y,beta-lactamase_39_179,TEM-1,beta-lactamase_39,P62593,0.152691,NO,179,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.085,-4.097,3.012,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.0495842,0.00226045,0.152691 kka2_1:8_G233H,kka2_1:8_233,Kka2,kka2_1:8,P00552,0.152705,NO,233,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.748,-4.708,3.96,,0.172,,b,0.75,-0.27,1.134,,49.24,HOO,-1.72067,0.100394,0.00232366,0.152705 kka2_1:8_G233H,kka2_1:8_233,Kka2,kka2_1:8,P00552,0.152705,NO,233,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.748,-4.708,3.96,,0.172,,b,0.75,-0.27,1.134,,49.24,HOO,-1.72067,0.100394,0.00232366,0.152705 kka2_1:2_H106F,kka2_1:2_106,Kka2,kka2_1:2,P00552,0.152774,NO,106,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-3.13,-4.435,1.305,,1.065,.,a,0.17,-0.95,2.53,,71.59,PBH,-2.10433,0.295029,0.00730778,0.152774 kka2_1:1_L260N,kka2_1:1_260,Kka2,kka2_1:1,P00552,0.152818,NO,260,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.741,-4.151,3.41,,0.022,H,A,0.55,-0.52,,,,HHA,-0.845667,0.520039,0.0233782,0.152818 kka2_1:4_P194Y,kka2_1:4_194,Kka2,kka2_1:4,P00552,0.152891,NO,194,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.846,-4.438,3.592,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.168804,0.00314194,0.152891 beta-lactamase_2500_A132W,beta-lactamase_2500_132,TEM-1,beta-lactamase_2500,P62593,0.152921,NO,132,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.9,-5.372,4.472,,,H,A,0.46,-0.93,8.408,,64.69,PHH,-1.138,0.361275,0.000962524,0.152921 beta-lactamase_156_G76P,beta-lactamase_156_76,TEM-1,beta-lactamase_156,P62593,0.152922,NO,76,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.189,-3.852,2.663,,,H,A,0.29,-0.67,3.059,,67.83,OOH,-1.22267,0.111618,0.00476637,0.152922 kka2_1:2_W69F,kka2_1:2_69,Kka2,kka2_1:2,P00552,0.152925,NO,69,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-0.859,-3.388,2.529,,0.164,H,A,0.47,0.15,5.074,,38.64,PHH,-1.49967,0.295029,0.0012874,0.152925 kka2_1:2_W69V,kka2_1:2_69,Kka2,kka2_1:2,P00552,0.152925,NO,69,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-0.859,-3.749,2.89,,0.164,H,A,0.47,0.15,5.074,,38.64,PHH,-1.49967,0.295029,0.0012874,0.152925 beta-lactamase_2500_R162Y,beta-lactamase_2500_162,TEM-1,beta-lactamase_2500,P62593,0.152938,NO,162,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.016,-4.207,3.191,,0.124,S,B,1.2,-0.37,6.199,,64.69,ABH,-1.25,0.361275,0.000561334,0.152938 beta-lactamase_E35W,beta-lactamase_35,TEM-1,beta-lactamase,P62593,0.152941,NO,35,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-0.869,-5.371,4.502,5.10723,0.15,H,A,0.52,0.21,1.081,,46.85,HAA,-1.88667,0.221079,0.00174441,0.152941 kka2_1:2_S204D,kka2_1:2_204,Kka2,kka2_1:2,P00552,0.152958,NO,204,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.353,-3.549,2.196,,0.144,E,A,0.27,-1.2,2.442,,65.53,HPO,-0.953333,0.295029,0.00881794,0.152958 beta-lactamase_156_M209D,beta-lactamase_156_209,TEM-1,beta-lactamase_156,P62593,0.153006,NO,209,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.442,-4.067,2.625,,,H,A,0.55,-0.97,1.066,,64.69,HHA,-1.52633,0.111618,0.00625021,0.153006 kka2_1:1_T187F,kka2_1:1_187,Kka2,kka2_1:1,P00552,0.153048,NO,187,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.273,-4.193,2.92,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.520039,0.00693073,0.153048 kka2_1:2_D216W,kka2_1:2_216,Kka2,kka2_1:2,P00552,0.153132,NO,216,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.785,-5.543,4.758,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.295029,0.00229969,0.153132 Ubiquitin_D21P,Ubiquitin_21,Uba1,Ubiquitin,P0CG48,0.153226,NO,21,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.193,-3.771,2.578,4.96432,0.165,,B,0.23,-0.53,1.013,,71.82,PAP,-1.35867,0.205827,0.000465257,0.153226 Ubiquitin_I3G,Ubiquitin_3,Uba1,Ubiquitin,P0CG48,0.153226,NO,3,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.402,-3.749,2.347,4.80819,,E,B,,-0.78,,,,PHH,-1.54533,0.205827,0.000836911,0.153226 beta-lactamase_R162P,beta-lactamase_162,TEM-1,beta-lactamase,P62593,0.153228,NO,162,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.016,-2.671,1.655,5.34456,0.124,S,B,0.68,-0.37,31.656,31.656,64.69,ABH,-1.25,0.221079,0.000561334,0.153228 kka2_1:2_P132D,kka2_1:2_132,Kka2,kka2_1:2,P00552,0.153295,NO,132,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.775,-3.495,2.72,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.295029,0.0018489,0.153295 beta-lactamase_625_G43H,beta-lactamase_625_43,TEM-1,beta-lactamase_625,P62593,0.153451,NO,43,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.62,-4.68,4.06,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.213352,0.00120151,0.153451 beta-lactamase_156_K71R,beta-lactamase_156_71,TEM-1,beta-lactamase_156,P62593,0.153492,NO,71,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-0.8,-3.033,2.233,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.111618,0.00103192,0.153492 kka2_1:4_I196H,kka2_1:4_196,Kka2,kka2_1:4,P00552,0.153502,NO,196,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-2.115,-4.791,2.676,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.168804,0.0107273,0.153502 kka2_1:1_T73I,kka2_1:1_73,Kka2,kka2_1:1,P00552,0.153503,NO,73,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.51,-3.77,1.26,,0.309,H,A,0.22,0.35,4.126,,56.06,PPO,-2.02333,0.520039,0.00628605,0.153503 kka2_1:2_G189N,kka2_1:2_189,Kka2,kka2_1:2,P00552,0.153517,NO,189,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.596,-3.476,2.88,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.295029,0.00253688,0.153517 kka2_1:2_D183F,kka2_1:2_183,Kka2,kka2_1:2,P00552,0.153528,NO,183,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.204,-4.408,3.204,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.295029,0.00426304,0.153528 beta-lactamase_156_G43H,beta-lactamase_156_43,TEM-1,beta-lactamase_156,P62593,0.153574,NO,43,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.62,-4.68,4.06,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.111618,0.00120151,0.153574 beta-lactamase_2500_W227K,beta-lactamase_2500_227,TEM-1,beta-lactamase_2500,P62593,0.153577,NO,227,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-0.982,-3.931,2.949,,0.272,,B,0.47,-0.29,1.37,,74.48,OHH,-1.595,0.361275,0.00226019,0.153577 kka2_1:1_V49P,kka2_1:1_49,Kka2,kka2_1:1,P00552,0.153577,NO,49,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.614,-4.128,2.514,,,E,B,0.44,-0.77,3.665,3.665,64.39,HHB,-1.3,0.520039,0.00615685,0.153577 kka2_1:4_I115G,kka2_1:4_115,Kka2,kka2_1:4,P00552,0.15365,NO,115,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.606,-3.814,2.208,,0.105,H,A,1.52,-1.18,9.996,9.996,65.53,PHH,-2.205,0.168804,0.00836567,0.15365 kka2_1:2_L158I,kka2_1:2_158,Kka2,kka2_1:2,P00552,0.153651,NO,158,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.947,-3.293,1.346,,0.095,,B,1.59,0.77,7.588,,63.64,AHA,-1.25333,0.295029,0.00529068,0.153651 beta-lactamase_2500_S68F,beta-lactamase_2500_68,TEM-1,beta-lactamase_2500,P62593,0.1537,NO,68,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-0.913,-4.116,3.203,,0.064,G,A,0.27,-1.03,2.824,,64.69,HPP,-1.37233,0.361275,0.000800065,0.1537 kka2_1:2_L19G,kka2_1:2_19,Kka2,kka2_1:2,P00552,0.153766,NO,19,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.254,-3.863,2.609,,0.08,T,A,0.55,-0.26,17.165,17.165,65.53,BHH,-2.221,0.295029,0.00620703,0.153766 kka2_1:2_L19K,kka2_1:2_19,Kka2,kka2_1:2,P00552,0.153766,NO,19,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.254,-3.899,2.645,,0.08,T,A,0.55,-0.26,17.165,17.165,65.53,BHH,-2.221,0.295029,0.00620703,0.153766 kka2_1:2_I196C,kka2_1:2_196,Kka2,kka2_1:2,P00552,0.153813,NO,196,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-2.115,-4.921,2.806,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.295029,0.0107273,0.153813 beta-lactamase_625_L205S,beta-lactamase_625_205,TEM-1,beta-lactamase_625,P62593,0.153831,NO,205,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.922,-3.629,2.707,,,H,A,0.55,-0.46,3.782,,42.31,PHH,-1.57767,0.213352,0.00255802,0.153831 beta-lactamase_2500_W288D,beta-lactamase_2500_288,TEM-1,beta-lactamase_2500,P62593,0.153834,NO,288,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,,,,,,,,,,,,,BHO,,0.361275,,0.153834 beta-lactamase_2500_V31N,beta-lactamase_2500_31,TEM-1,beta-lactamase_2500,P62593,0.153862,NO,31,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.822,-4.194,2.372,,,H,A,0.44,-0.46,0.955,,73.78,BHB,-2.03767,0.361275,0.00478065,0.153862 beta-lactamase_2500_A132Y,beta-lactamase_2500_132,TEM-1,beta-lactamase_2500,P62593,0.153919,NO,132,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.9,-4.186,3.286,,,H,A,0.46,-0.93,8.408,,64.69,PHH,-1.138,0.361275,0.000962524,0.153919 beta-lactamase_625_I261Q,beta-lactamase_625_261,TEM-1,beta-lactamase_625,P62593,0.153952,NO,261,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.213352,0.0123091,0.153952 beta-lactamase_625_I261N,beta-lactamase_625_261,TEM-1,beta-lactamase_625,P62593,0.153956,NO,261,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.213352,0.0123091,0.153956 Pab1_I152K,Pab1_152,Pab1,Pab1,P04147,0.153967,NO,152,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.345,-3.72,2.375,,0.165,E,B,1.23,-0.71,1.288,,71.4,AHH,-1.59433,0.175299,0.000740963,0.153967 kka2_1:8_A78F,kka2_1:8_78,Kka2,kka2_1:8,P00552,0.154005,NO,78,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.744,-4.44,2.696,,0.078,,B,1.04,-0.53,1.251,,56.06,OHH,-1.863,0.100394,0.00457299,0.154005 kka2_1:8_A78F,kka2_1:8_78,Kka2,kka2_1:8,P00552,0.154005,NO,78,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.744,-4.44,2.696,,0.078,,B,1.04,-0.53,1.251,,56.06,OHH,-1.863,0.100394,0.00457299,0.154005 beta-lactamase_2500_S128N,beta-lactamase_2500_128,TEM-1,beta-lactamase_2500,P62593,0.154094,NO,128,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-0.84,-3.223,2.383,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.361275,0.00071483,0.154094 kka2_1:2_W24D,kka2_1:2_24,Kka2,kka2_1:2,P00552,0.154125,NO,24,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-1.779,-4.166,2.387,,0.477,E,B,1.51,-0.21,2.666,,56.06,AHH,-2.24467,0.295029,0.00631564,0.154125 beta-lactamase_156_T179N,beta-lactamase_156_179,TEM-1,beta-lactamase_156,P62593,0.154128,NO,179,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.085,-3.487,2.402,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.111618,0.00226045,0.154128 beta-lactamase_625_I229R,beta-lactamase_625_229,TEM-1,beta-lactamase_625,P62593,0.154175,NO,229,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.267,-4.174,2.907,,0.083,E,B,0.48,-0.76,1.69,,50,HHH,-1.58767,0.213352,0.00477249,0.154175 kka2_1:8_G233F,kka2_1:8_233,Kka2,kka2_1:8,P00552,0.154221,NO,233,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.748,-4.365,3.617,,0.172,,b,0.75,-0.27,1.134,,49.24,HOO,-1.72067,0.100394,0.00232366,0.154221 kka2_1:8_G233F,kka2_1:8_233,Kka2,kka2_1:8,P00552,0.154221,NO,233,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.748,-4.365,3.617,,0.172,,b,0.75,-0.27,1.134,,49.24,HOO,-1.72067,0.100394,0.00232366,0.154221 beta-lactamase_2500_T158D,beta-lactamase_2500_158,TEM-1,beta-lactamase_2500,P62593,0.154248,NO,158,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.116,-3.478,2.362,,0.036,,B,0.22,-0.85,1.344,,69.58,HPB,-1.269,0.361275,0.00341825,0.154248 kka2_1:2_H188G,kka2_1:2_188,Kka2,kka2_1:2,P00552,0.154329,NO,188,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-0.913,-3.41,2.497,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.295029,0.00273139,0.154329 beta-lactamase_39_E164N,beta-lactamase_39_164,TEM-1,beta-lactamase_39,P62593,0.154345,NO,164,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-0.948,-3.497,2.549,,0.011,T,B,1.04,-0.4,0.664,,64.69,HAO,-1.388,0.0495842,0.00137286,0.154345 kka2_1:1_N200G,kka2_1:1_200,Kka2,kka2_1:1,P00552,0.154358,NO,200,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-2.446,-1.948,-0.498,,0.756,T,L,0.61,-0.08,17.299,17.299,64.39,APO,-2.08,0.520039,0.00838549,0.154358 beta-lactamase_625_K71I,beta-lactamase_625_71,TEM-1,beta-lactamase_625,P62593,0.154359,NO,71,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-0.8,-4.01,3.21,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.213352,0.00103192,0.154359 kka2_1:2_L93H,kka2_1:2_93,Kka2,kka2_1:2,P00552,0.154537,NO,93,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.815,-4.864,4.049,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.295029,0.00131498,0.154537 beta-lactamase_625_L120E,beta-lactamase_625_120,TEM-1,beta-lactamase_625,P62593,0.154582,NO,120,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.044,-3.83,2.786,,,H,A,0.55,-1.13,7.813,,64.69,AHO,-1.13633,0.213352,0.00143563,0.154582 kka2_1:1_F203P,kka2_1:1_203,Kka2,kka2_1:1,P00552,0.15471,NO,203,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-0.911,-4.356,3.445,,0.26,E,B,0.58,-0.92,7.323,,63.64,BHP,-1.34167,0.520039,0.00318738,0.15471 beta-lactamase_625_I229P,beta-lactamase_625_229,TEM-1,beta-lactamase_625,P62593,0.154759,NO,229,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.267,-4.079,2.812,,0.083,E,B,0.48,-0.76,1.69,,50,HHH,-1.58767,0.213352,0.00477249,0.154759 beta-lactamase_156_A185Q,beta-lactamase_156_185,TEM-1,beta-lactamase_156,P62593,0.154801,NO,185,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.406,-4.108,2.702,,,H,A,0.46,-1.02,0.365,,65.03,HHP,-1.84033,0.111618,0.00467449,0.154801 beta-lactamase_625_L146E,beta-lactamase_625_146,TEM-1,beta-lactamase_625,P62593,0.154839,NO,146,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.462,-3.93,2.468,,0.007,H,A,0.55,-0.56,2.16,,64.69,AHP,-1.656,0.213352,0.00474542,0.154839 beta-lactamase_M1K,beta-lactamase_1,TEM-1,beta-lactamase,P62593,0.154857,NO,1,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.998,-3.139,1.141,,,,,,,,,,OHP,-1.97,0.221079,0.00162771,0.154857 kka2_1:2_D159I,kka2_1:2_159,Kka2,kka2_1:2,P00552,0.154888,NO,159,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.82,-4.102,3.282,,0.28,.,B,0.75,1.25,0.899,,48.11,HAA,-1.48333,0.295029,0.0030485,0.154888 kka2_1:1_H106F,kka2_1:1_106,Kka2,kka2_1:1,P00552,0.154889,NO,106,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-3.13,-4.435,1.305,,1.065,.,a,0.17,-0.95,2.53,,71.59,PBH,-2.10433,0.520039,0.00730778,0.154889 beta-lactamase_156_L120K,beta-lactamase_156_120,TEM-1,beta-lactamase_156,P62593,0.15489,NO,120,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.044,-3.668,2.624,,,H,A,0.55,-1.13,7.813,,64.69,AHO,-1.13633,0.111618,0.00143563,0.15489 beta-lactamase_625_G243P,beta-lactamase_625_243,TEM-1,beta-lactamase_625,P62593,0.154891,NO,243,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.213352,0.00464034,0.154891 kka2_1:2_A222L,kka2_1:2_222,Kka2,kka2_1:2,P00552,0.154906,NO,222,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.725,-3.161,2.436,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.295029,0.00207657,0.154906 kka2_1:2_K50A,kka2_1:2_50,Kka2,kka2_1:2,P00552,0.154926,NO,50,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-0.833,-3.129,2.296,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.295029,0.00138626,0.154926 beta-lactamase_2500_T158W,beta-lactamase_2500_158,TEM-1,beta-lactamase_2500,P62593,0.154934,NO,158,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.116,-5.268,4.152,,0.036,,B,0.22,-0.85,1.344,,69.58,HPB,-1.269,0.361275,0.00341825,0.154934 beta-lactamase_625_D129P,beta-lactamase_625_129,TEM-1,beta-lactamase_625,P62593,0.154938,NO,129,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.816,-3.68,2.864,,,,B,0.75,-0.69,0.171,,34.97,PAP,-0.818,0.213352,0.00109178,0.154938 beta-lactamase_625_S68V,beta-lactamase_625_68,TEM-1,beta-lactamase_625,P62593,0.154956,NO,68,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-0.913,-3.578,2.665,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.213352,0.000800065,0.154956 beta-lactamase_2500_L188P,beta-lactamase_2500_188,TEM-1,beta-lactamase_2500,P62593,0.154988,NO,188,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.166,-4.109,2.943,,,H,A,0.55,-0.3,17.865,17.865,60.14,PHB,-1.47033,0.361275,0.00295687,0.154988 kka2_1:1_V49F,kka2_1:1_49,Kka2,kka2_1:1,P00552,0.155034,NO,49,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.614,-3.894,2.28,,,E,B,0.44,-0.77,3.665,3.665,64.39,HHB,-1.3,0.520039,0.00615685,0.155034 kka2_1:1_A215M,kka2_1:1_215,Kka2,kka2_1:1,P00552,0.155049,NO,215,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.968,-4.593,3.625,,0.039,E,B,0.46,-0.59,0.754,,50.38,HHA,-1.00467,0.520039,0.00529129,0.155049 beta-lactamase_A276P,beta-lactamase_276,TEM-1,beta-lactamase,P62593,0.155156,NO,276,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.144,-3.781,2.637,5.1387,0.117,H,A,0.52,-0.84,1.283,,44.06,HHA,-1.47,0.221079,0.0191712,0.155156 kka2_1:2_D159K,kka2_1:2_159,Kka2,kka2_1:2,P00552,0.155181,NO,159,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.82,-3.549,2.729,,0.28,.,B,0.75,1.25,0.899,,48.11,HAA,-1.48333,0.295029,0.0030485,0.155181 beta-lactamase_625_G234T,beta-lactamase_625_234,TEM-1,beta-lactamase_625,P62593,0.155211,NO,234,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.62,-3.646,3.026,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.213352,0.000889577,0.155211 kka2_1:1_S104K,kka2_1:1_104,Kka2,kka2_1:1,P00552,0.155276,NO,104,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.436,-3.48,2.044,,0.536,T,A,0.27,-1.11,5.49,,63.64,HPP,-1.91433,0.520039,0.00555207,0.155276 kka2_1:2_E262Y,kka2_1:2_262,Kka2,kka2_1:2,P00552,0.155298,NO,262,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-0.829,-4.189,3.36,,0.059,G,A,1.04,-0.18,2.383,,42.42,AAH,-0.816,0.295029,0.0191586,0.155298 kka2_1:8_F240E,kka2_1:8_240,Kka2,kka2_1:8,P00552,0.155299,NO,240,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-0.911,-3.952,3.041,,,H,A,1.62,-1.21,0.697,,50.38,BHH,-1.67267,0.100394,0.00552543,0.155299 kka2_1:8_F240E,kka2_1:8_240,Kka2,kka2_1:8,P00552,0.155299,NO,240,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-0.911,-3.952,3.041,,,H,A,1.62,-1.21,0.697,,50.38,BHH,-1.67267,0.100394,0.00552543,0.155299 kka2_1:8_T187K,kka2_1:8_187,Kka2,kka2_1:8,P00552,0.155299,NO,187,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.273,-3.655,2.382,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.100394,0.00693073,0.155299 kka2_1:8_T187K,kka2_1:8_187,Kka2,kka2_1:8,P00552,0.155299,NO,187,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.273,-3.655,2.382,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.100394,0.00693073,0.155299 beta-lactamase_625_A230Y,beta-lactamase_625_230,TEM-1,beta-lactamase_625,P62593,0.155328,NO,230,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.154,-4.312,3.158,,0.01,E,B,0.46,-1.17,0.777,,50,HHA,-1.079,0.213352,0.00516841,0.155328 beta-lactamase_M66P,beta-lactamase_66,TEM-1,beta-lactamase,P62593,0.155484,NO,66,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.362,-4.047,2.685,5.29561,0.013,,A,1.3,-0.7,1.319,,73.08,OHH,-1.49567,0.221079,0.00412876,0.155484 beta-lactamase_2500_L192N,beta-lactamase_2500_192,TEM-1,beta-lactamase_2500,P62593,0.155538,NO,192,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.254,-4.206,2.952,,0.095,H,A,0.55,0.35,1.902,,60.14,HHP,-1.41833,0.361275,0.00558728,0.155538 beta-lactamase_625_T158N,beta-lactamase_625_158,TEM-1,beta-lactamase_625,P62593,0.155576,NO,158,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.116,-3.488,2.372,,0.036,,B,0.22,-0.85,3.771,,69.58,HPB,-1.269,0.213352,0.00341825,0.155576 kka2_1:2_F206G,kka2_1:2_206,Kka2,kka2_1:2,P00552,0.155596,NO,206,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.349,-3.746,2.397,,0.006,E,B,0.58,-1.21,0.978,,63.64,OHH,-1.04,0.295029,0.00936868,0.155596 beta-lactamase_2500_L135P,beta-lactamase_2500_135,TEM-1,beta-lactamase_2500,P62593,0.155625,NO,135,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.002,-4.134,3.132,,0.117,H,A,0.55,-0.58,0.795,,43.71,PHH,-1.03767,0.361275,0.00244423,0.155625 kka2_1:1_A137P,kka2_1:1_137,Kka2,kka2_1:1,P00552,0.155635,NO,137,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.156,-4.148,1.992,,0.029,H,A,0.46,0.34,1.323,,63.26,PHB,-2.559,0.520039,0.00515054,0.155635 kka2_1:1_Y244D,kka2_1:1_244,Kka2,kka2_1:1,P00552,0.155646,NO,244,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-0.775,-3.947,3.172,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.520039,0.00453187,0.155646 kka2_1:1_L212W,kka2_1:1_212,Kka2,kka2_1:1,P00552,0.155667,NO,212,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.904,-5.226,4.322,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.520039,0.0031426,0.155667 beta-lactamase_2500_G240K,beta-lactamase_2500_240,TEM-1,beta-lactamase_2500,P62593,0.155773,NO,240,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.361275,0.00591201,0.155773 kka2_1:2_L232G,kka2_1:2_232,Kka2,kka2_1:2,P00552,0.155795,NO,232,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.514,-2.969,1.455,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.295029,0.00800103,0.155795 kka2_1:2_C209W,kka2_1:2_209,Kka2,kka2_1:2,P00552,0.15583,NO,209,C,W,CW,Special,Hydrophobic,5.07,5.89,0.82,215,121,204,83,108.5,227.8,119.3,-0.906,-5.149,4.243,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.295029,0.00260862,0.15583 beta-lactamase_156_I261E,beta-lactamase_156_261,TEM-1,beta-lactamase_156,P62593,0.155861,NO,261,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.111618,0.0123091,0.155861 beta-lactamase_39_E164S,beta-lactamase_39_164,TEM-1,beta-lactamase_39,P62593,0.155903,NO,164,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-0.948,-3.21,2.262,,0.011,T,B,1.04,-0.4,0.664,,64.69,HAO,-1.388,0.0495842,0.00137286,0.155903 kka2_1:2_L232W,kka2_1:2_232,Kka2,kka2_1:2,P00552,0.155986,NO,232,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.514,-3.426,1.912,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.295029,0.00800103,0.155986 beta-lactamase_2500_E35F,beta-lactamase_2500_35,TEM-1,beta-lactamase_2500,P62593,0.156026,NO,35,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-0.869,-4.318,3.449,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.361275,0.00174441,0.156026 beta-lactamase_625_F64T,beta-lactamase_625_64,TEM-1,beta-lactamase_625,P62593,0.156072,NO,64,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-0.841,-3.646,2.805,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.213352,0.000947691,0.156072 kka2_1:2_G205W,kka2_1:2_205,Kka2,kka2_1:2,P00552,0.156202,NO,205,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.596,-5.126,4.53,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.295029,0.00221855,0.156202 beta-lactamase_2500_V117R,beta-lactamase_2500_117,TEM-1,beta-lactamase_2500,P62593,0.156208,NO,117,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.53,-4.17,2.64,,,H,A,0.44,-0.34,1.23,,65.03,PHB,-1.741,0.361275,0.00467906,0.156208 beta-lactamase_156_C75P,beta-lactamase_156_75,TEM-1,beta-lactamase_156,P62593,0.156237,NO,75,C,P,CP,Special,Special,5.07,6.3,1.23,169,121,115,-6,108.5,112.7,4.2,-1.245,-4.012,2.767,,,H,A,0.46,-0.87,0.876,,50,HOO,-1.24333,0.111618,0.0034616,0.156237 beta-lactamase_625_F64P,beta-lactamase_625_64,TEM-1,beta-lactamase_625,P62593,0.156259,NO,64,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-0.841,-4.33,3.489,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.213352,0.000947691,0.156259 beta-lactamase_F64S,beta-lactamase_64,TEM-1,beta-lactamase,P62593,0.156338,NO,64,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-0.841,-3.611,2.77,5.70769,0.006,E,B,1.33,-0.95,,,,BHO,-0.892667,0.221079,0.000947691,0.156338 kka2_1:1_T73F,kka2_1:1_73,Kka2,kka2_1:1,P00552,0.156379,NO,73,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.51,-4.242,1.732,,0.309,H,A,0.22,0.35,4.126,,56.06,PPO,-2.02333,0.520039,0.00628605,0.156379 beta-lactamase_39_G76K,beta-lactamase_39_76,TEM-1,beta-lactamase_39,P62593,0.156411,NO,76,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.189,-3.631,2.442,,,H,A,0.29,-0.67,2.145,,67.83,OOH,-1.22267,0.0495842,0.00476637,0.156411 beta-lactamase_39_L136P,beta-lactamase_39_136,TEM-1,beta-lactamase_39,P62593,0.156468,NO,136,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.232,-4.152,2.92,,,H,A,0.55,-0.34,0.336,,48.95,HHH,-1.088,0.0495842,0.00442304,0.156468 beta-lactamase_625_D177R,beta-lactamase_625_177,TEM-1,beta-lactamase_625,P62593,0.156469,NO,177,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.967,-3.931,2.964,,0.006,T,L,0.75,-1.02,1.333,,64.69,BAP,-0.873667,0.213352,0.000864022,0.156469 beta-lactamase_156_K71H,beta-lactamase_156_71,TEM-1,beta-lactamase_156,P62593,0.156492,NO,71,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-0.8,-4.455,3.655,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.111618,0.00103192,0.156492 hsp90_A587E,hsp90_587,hsp90,hsp90,P02829,0.156562,NO,587,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.456,-2.818,0,4.91216,0.049,H,A,0.55,-0.02,,,,PHP,-2.757,0.368192,0.000222939,0.156562 beta-lactamase_D155I,beta-lactamase_155,TEM-1,beta-lactamase,P62593,0.156572,NO,155,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.889,-4.06,3.171,4.92265,0.049,,B,0.45,-0.9,3.208,,64.69,OAB,-1.62267,0.221079,0.00135315,0.156572 beta-lactamase_0_A123E,beta-lactamase_0_123,TEM-1,beta-lactamase_0,P62593,0.156631,NO,123,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.834,-3.489,2.655,,0.039,H,A,0.46,-0.72,1.308,,41.26,PHH,-1.47367,0.0500837,0.0010157,0.156631 kka2_1:1_A166Y,kka2_1:1_166,Kka2,kka2_1:1,P00552,0.156777,NO,166,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.407,-4.444,2.037,,0.534,.,B,0.46,1.03,1.147,,71.59,HHO,-2.421,0.520039,0.00799912,0.156777 kka2_1:4_F263P,kka2_1:4_263,Kka2,kka2_1:4,P00552,0.156799,NO,263,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-0.911,-4.356,3.445,,0.006,G,A,0.58,-0.12,2.284,,45.83,AHH,-0.92,0.168804,0.0172454,0.156799 kka2_1:4_L92Y,kka2_1:4_92,Kka2,kka2_1:4,P00552,0.156812,NO,92,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.893,-4.021,3.128,,0.007,E,B,0.55,-0.19,1.447,,63.26,HHH,-0.962,0.168804,0.00307177,0.156812 beta-lactamase_D177I,beta-lactamase_177,TEM-1,beta-lactamase,P62593,0.156893,NO,177,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.967,-4.048,3.081,5.08038,0.006,T,L,1.59,-1.02,3.536,,64.69,BAP,-0.873667,0.221079,0.000864022,0.156893 kka2_1:8_V186S,kka2_1:8_186,Kka2,kka2_1:8,P00552,0.157017,NO,186,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.011,-3.722,2.711,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.100394,0.00409703,0.157017 kka2_1:8_V186S,kka2_1:8_186,Kka2,kka2_1:8,P00552,0.157017,NO,186,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.011,-3.722,2.711,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.100394,0.00409703,0.157017 beta-lactamase_M184K,beta-lactamase_184,TEM-1,beta-lactamase,P62593,0.157029,NO,184,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.593,-3.659,2.066,5.39575,,H,A,1.3,-0.87,2.893,,62.94,HHH,-1.41,0.221079,0.00356019,0.157029 kka2_1:1_V36W,kka2_1:1_36,Kka2,kka2_1:1,P00552,0.157123,NO,36,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-0.898,-5.395,4.497,,0.292,E,B,0.44,0.21,0.278,,52.27,HHH,-1.484,0.520039,0.00245633,0.157123 beta-lactamase_156_K232S,beta-lactamase_156_232,TEM-1,beta-lactamase_156,P62593,0.157175,NO,232,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.012,-3.258,2.246,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.111618,0.00313441,0.157175 kka2_1:1_A78P,kka2_1:1_78,Kka2,kka2_1:1,P00552,0.157205,NO,78,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.744,-0.97,-0.774,,0.078,.,B,0.46,-0.53,0.206,,56.06,OHH,-1.863,0.520039,0.00457299,0.157205 beta-lactamase_2500_T158N,beta-lactamase_2500_158,TEM-1,beta-lactamase_2500,P62593,0.157243,NO,158,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.116,-3.488,2.372,,0.036,,B,0.22,-0.85,1.344,,69.58,HPB,-1.269,0.361275,0.00341825,0.157243 kka2_1:1_E96Y,kka2_1:1_96,Kka2,kka2_1:1,P00552,0.157252,NO,96,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.573,-4.313,1.74,,0.476,,B,1.52,-0.65,1.254,,71.59,OAH,-2.143,0.520039,0.00369441,0.157252 kka2_1:1_V153E,kka2_1:1_153,Kka2,kka2_1:1,P00552,0.157252,NO,153,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.092,-3.813,2.721,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.520039,0.00501119,0.157252 E1_Ubiquitin_G76T,E1_Ubiquitin_76,Uba1,E1_Ubiquitin,P0CG63,0.157383,NO,76,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.999,-3.517,2.518,,0.23,,B,0.75,0.08,1.702,,83.73,OOO,-0.999,0.18783,0.00125575,0.157383 kka2_1:1_V214D,kka2_1:1_214,Kka2,kka2_1:1,P00552,0.157417,NO,214,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.261,-4.099,2.838,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.520039,0.00692782,0.157417 beta-lactamase_625_G240P,beta-lactamase_625_240,TEM-1,beta-lactamase_625,P62593,0.157447,NO,240,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.213352,0.00591201,0.157447 beta-lactamase_156_W227Q,beta-lactamase_156_227,TEM-1,beta-lactamase_156,P62593,0.157493,NO,227,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-0.982,-4.194,3.212,,0.272,,B,0.47,-0.29,2.533,,74.48,OHH,-1.595,0.111618,0.00226019,0.157493 beta-lactamase_156_E164L,beta-lactamase_156_164,TEM-1,beta-lactamase_156,P62593,0.157501,NO,164,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-0.948,-3.627,2.679,,0.011,T,B,1.04,-0.4,3.445,,64.69,HAO,-1.388,0.111618,0.00137286,0.157501 Pab1_F170R,Pab1_170,Pab1,Pab1,P04147,0.157509,NO,170,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.269,-3.969,2.7,,0.331,E,B,0.87,-1.31,2.061,,79.72,OHH,-1.06367,0.175299,0.000540225,0.157509 kka2_1:2_P45I,kka2_1:2_45,Kka2,kka2_1:2,P00552,0.157528,NO,45,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.774,-4.097,2.323,,0.669,,B,0.52,-0.76,4.882,,71.59,BOH,-2.152,0.295029,0.00590481,0.157528 kka2_1:1_I196M,kka2_1:1_196,Kka2,kka2_1:1,P00552,0.157544,NO,196,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-2.115,-3.213,1.098,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.520039,0.0107273,0.157544 beta-lactamase_156_G234L,beta-lactamase_156_234,TEM-1,beta-lactamase_156,P62593,0.157549,NO,234,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.62,-3.808,3.188,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.111618,0.000889577,0.157549 beta-lactamase_156_L136E,beta-lactamase_156_136,TEM-1,beta-lactamase_156,P62593,0.157583,NO,136,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.232,-3.938,2.706,,,H,A,0.55,-0.34,1.04,,48.95,HHH,-1.088,0.111618,0.00442304,0.157583 kka2_1:1_L243G,kka2_1:1_243,Kka2,kka2_1:1,P00552,0.157593,NO,243,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-2.651,-3.604,0.953,,0.277,H,A,0.55,-0.67,4.334,,92.05,HHH,-2.03767,0.520039,0.00884927,0.157593 kka2_1:2_F48Q,kka2_1:2_48,Kka2,kka2_1:2,P00552,0.157664,NO,48,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.453,-4.352,2.899,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.295029,0.00475422,0.157664 beta-lactamase_625_S233I,beta-lactamase_625_233,TEM-1,beta-lactamase_625,P62593,0.157673,NO,233,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.886,-3.784,1.898,,0.016,E,B,0.27,-1.01,1.773,,77.62,BPO,-1.17267,0.213352,0.00311415,0.157673 beta-lactamase_625_E56P,beta-lactamase_625_56,TEM-1,beta-lactamase_625,P62593,0.157675,NO,56,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.043,-3.731,1.688,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.213352,0.00238534,0.157675 beta-lactamase_2500_L248D,beta-lactamase_2500_248,TEM-1,beta-lactamase_2500,P62593,0.157751,NO,248,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.361275,0.00428493,0.157751 kka2_1:2_V185T,kka2_1:2_185,Kka2,kka2_1:2,P00552,0.157761,NO,185,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.045,-3.363,2.318,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.295029,0.00367031,0.157761 kka2_1:2_F203D,kka2_1:2_203,Kka2,kka2_1:2,P00552,0.157828,NO,203,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-0.911,-4.011,3.1,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.295029,0.00318738,0.157828 beta-lactamase_625_L205E,beta-lactamase_625_205,TEM-1,beta-lactamase_625,P62593,0.157862,NO,205,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.922,-3.908,2.986,,,H,A,0.55,-0.46,3.782,,42.31,PHH,-1.57767,0.213352,0.00255802,0.157862 beta-lactamase_2500_L191R,beta-lactamase_2500_191,TEM-1,beta-lactamase_2500,P62593,0.157865,NO,191,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.087,-4.02,2.933,,,H,A,0.55,0.09,1.703,,63.29,BHH,-1.445,0.361275,0.00263549,0.157865 beta-lactamase_2500_D177F,beta-lactamase_2500_177,TEM-1,beta-lactamase_2500,P62593,0.157884,NO,177,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.967,-4.34,3.373,,0.006,T,L,0.75,-1.02,4.131,,64.69,BAP,-0.873667,0.361275,0.000864022,0.157884 kka2_1:4_I207Y,kka2_1:4_207,Kka2,kka2_1:4,P00552,0.157885,NO,207,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.175,-4.053,2.878,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.168804,0.00611824,0.157885 beta-lactamase_2500_I261H,beta-lactamase_2500_261,TEM-1,beta-lactamase_2500,P62593,0.157991,NO,261,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.361275,0.0123091,0.157991 beta-lactamase_625_G43D,beta-lactamase_625_43,TEM-1,beta-lactamase_625,P62593,0.158045,NO,43,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.62,-3.469,2.849,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.213352,0.00120151,0.158045 kka2_1:1_V80N,kka2_1:1_80,Kka2,kka2_1:1,P00552,0.158052,NO,80,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.144,-4.197,3.053,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.520039,0.00488211,0.158052 kka2_1:4_V185Q,kka2_1:4_185,Kka2,kka2_1:4,P00552,0.158067,NO,185,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.045,-4.205,3.16,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.168804,0.00367031,0.158067 kka2_1:8_H135S,kka2_1:8_135,Kka2,kka2_1:8,P00552,0.158086,NO,135,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-1.331,-3.439,2.108,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.100394,0.00532566,0.158086 kka2_1:8_H135S,kka2_1:8_135,Kka2,kka2_1:8,P00552,0.158086,NO,135,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-1.331,-3.439,2.108,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.100394,0.00532566,0.158086 beta-lactamase_625_S68G,beta-lactamase_625_68,TEM-1,beta-lactamase_625,P62593,0.158092,NO,68,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-0.913,-2.934,2.021,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.213352,0.000800065,0.158092 beta-lactamase_M1Q,beta-lactamase_1,TEM-1,beta-lactamase,P62593,0.158115,NO,1,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.998,-3.356,1.358,,,,,,,,,,OHP,-1.97,0.221079,0.00162771,0.158115 kka2_1:2_G43I,kka2_1:2_43,Kka2,kka2_1:2,P00552,0.15818,NO,43,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.587,-4.201,2.614,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.295029,0.0071925,0.15818 beta-lactamase_2500_A185F,beta-lactamase_2500_185,TEM-1,beta-lactamase_2500,P62593,0.158223,NO,185,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.406,-4.091,2.685,,,H,A,0.46,-1.02,2.999,,65.03,HHP,-1.84033,0.361275,0.00467449,0.158223 beta-lactamase_2500_D129T,beta-lactamase_2500_129,TEM-1,beta-lactamase_2500,P62593,0.158223,NO,129,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.816,-3.447,2.631,,,,B,0.75,-0.69,1.29,,34.97,PAP,-0.818,0.361275,0.00109178,0.158223 kka2_1:2_W236T,kka2_1:2_236,Kka2,kka2_1:2,P00552,0.158253,NO,236,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-1.363,-3.713,2.35,,0.303,H,A,1.51,-0.76,5.58,,48.48,AHH,-1.81267,0.295029,0.0088796,0.158253 beta-lactamase_G239L,beta-lactamase_239,TEM-1,beta-lactamase,P62593,0.158266,NO,239,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.819,-3.712,2.893,4.85529,0.115,T,l,0.77,-0.62,1.817,,42.31,BOP,-1.45267,0.221079,0.00213852,0.158266 beta-lactamase_S80P,beta-lactamase_80,TEM-1,beta-lactamase,P62593,0.158317,NO,80,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.029,-3.939,1.91,5.23748,0.192,H,A,0.25,0.46,2.256,,77.62,HPB,-1.44567,0.221079,0.00565569,0.158317 kka2_1:4_D208Q,kka2_1:4_208,Kka2,kka2_1:4,P00552,0.158368,NO,208,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.708,-3.703,2.995,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.168804,0.00212588,0.158368 beta-lactamase_625_I280K,beta-lactamase_625_280,TEM-1,beta-lactamase_625,P62593,0.158457,NO,280,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.213352,0.0530888,0.158457 beta-lactamase_625_M184W,beta-lactamase_625_184,TEM-1,beta-lactamase_625,P62593,0.1585,NO,184,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.593,-5.149,3.556,,,H,A,0.55,-0.87,2.765,,62.94,HHH,-1.41,0.213352,0.00356019,0.1585 beta-lactamase_156_G249L,beta-lactamase_156_249,TEM-1,beta-lactamase_156,P62593,0.158557,NO,249,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.111618,0.00220169,0.158557 beta-lactamase_39_S128M,beta-lactamase_39_128,TEM-1,beta-lactamase_39,P62593,0.15866,NO,128,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-0.84,-4.48,3.64,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.0495842,0.00071483,0.15866 beta-lactamase_2500_A124P,beta-lactamase_2500_124,TEM-1,beta-lactamase_2500,P62593,0.158671,NO,124,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.181,-3.759,2.578,,,H,A,0.46,-0.9,0.314,,64.34,HHH,-1.152,0.361275,0.00481399,0.158671 kka2_1:8_L260H,kka2_1:8_260,Kka2,kka2_1:8,P00552,0.158725,NO,260,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.741,-4.933,4.192,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.100394,0.0233782,0.158725 kka2_1:8_L260H,kka2_1:8_260,Kka2,kka2_1:8,P00552,0.158725,NO,260,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.741,-4.933,4.192,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.100394,0.0233782,0.158725 kka2_1:2_G245Y,kka2_1:2_245,Kka2,kka2_1:2,P00552,0.158759,NO,245,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.812,-4.419,3.607,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.295029,0.00683899,0.158759 beta-lactamase_156_G43N,beta-lactamase_156_43,TEM-1,beta-lactamase_156,P62593,0.158813,NO,43,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.62,-3.448,2.828,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.111618,0.00120151,0.158813 beta-lactamase_D155A,beta-lactamase_155,TEM-1,beta-lactamase,P62593,0.15883,NO,155,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.889,-3.327,2.438,4.92265,0.049,,B,0.45,-0.9,3.208,,64.69,OAB,-1.62267,0.221079,0.00135315,0.15883 beta-lactamase_2500_D174M,beta-lactamase_2500_174,TEM-1,beta-lactamase_2500,P62593,0.158858,NO,174,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.738,-4.93,4.192,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.361275,0.00125633,0.158858 beta-lactamase_N130V,beta-lactamase_130,TEM-1,beta-lactamase,P62593,0.158867,NO,130,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-0.798,-3.754,2.956,5.26686,0.069,H,A,1.08,-0.74,,,,APP,-0.980667,0.221079,0.000683376,0.158867 kka2_1:8_G213Q,kka2_1:8_213,Kka2,kka2_1:8,P00552,0.158938,NO,213,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.596,-4.153,3.557,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.100394,0.00187654,0.158938 kka2_1:8_G213Q,kka2_1:8_213,Kka2,kka2_1:8,P00552,0.158938,NO,213,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.596,-4.153,3.557,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.100394,0.00187654,0.158938 beta-lactamase_2500_I125G,beta-lactamase_2500_125,TEM-1,beta-lactamase_2500,P62593,0.158943,NO,125,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.441,-3.768,2.327,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.361275,0.00383964,0.158943 beta-lactamase_625_V31D,beta-lactamase_625_31,TEM-1,beta-lactamase_625,P62593,0.158951,NO,31,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.822,-4.049,2.227,,,H,A,0.44,-0.46,2.576,,73.78,BHB,-2.03767,0.213352,0.00478065,0.158951 beta-lactamase_2500_T27W,beta-lactamase_2500_27,TEM-1,beta-lactamase_2500,P62593,0.158985,NO,27,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.905,-5.314,3.409,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.361275,0.00306559,0.158985 beta-lactamase_0_T126H,beta-lactamase_0_126,TEM-1,beta-lactamase_0,P62593,0.158997,NO,126,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.122,-4.699,3.577,,0.05,H,A,0.22,-0.05,0.705,,44.41,HPH,-1.60467,0.0500837,0.00244552,0.158997 kka2_1:2_F203A,kka2_1:2_203,Kka2,kka2_1:2,P00552,0.15902,NO,203,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-0.911,-3.329,2.418,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.295029,0.00318738,0.15902 beta-lactamase_39_D129I,beta-lactamase_39_129,TEM-1,beta-lactamase_39,P62593,0.159025,NO,129,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.816,-4.036,3.22,,,,B,0.75,-0.69,0.56,,34.97,PAP,-0.818,0.0495842,0.00109178,0.159025 kka2_1:1_L47T,kka2_1:1_47,Kka2,kka2_1:1,P00552,0.159035,NO,47,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.265,-3.56,2.295,,0.139,E,B,0.55,-0.86,14.593,14.593,63.26,HHH,-1.77933,0.520039,0.00509386,0.159035 kka2_1:2_L193H,kka2_1:2_193,Kka2,kka2_1:2,P00552,0.159042,NO,193,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.983,-4.891,3.908,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.295029,0.00480179,0.159042 kka2_1:4_L193Y,kka2_1:4_193,Kka2,kka2_1:4,P00552,0.159099,NO,193,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.983,-4.078,3.095,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.168804,0.00480179,0.159099 beta-lactamase_625_K232C,beta-lactamase_625_232,TEM-1,beta-lactamase_625,P62593,0.159135,NO,232,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.012,-5.13,4.118,,,E,B,2.34,-1.1,1.992,,65.03,ABP,-1.238,0.213352,0.00313441,0.159135 kka2_1:2_L47D,kka2_1:2_47,Kka2,kka2_1:2,P00552,0.159141,NO,47,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.265,-4.048,2.783,,0.139,E,B,0.55,-0.86,2.369,,63.26,HHH,-1.77933,0.295029,0.00509386,0.159141 kka2_1:1_D159K,kka2_1:1_159,Kka2,kka2_1:1,P00552,0.159142,NO,159,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.82,-3.549,2.729,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.520039,0.0030485,0.159142 kka2_1:1_V186Y,kka2_1:1_186,Kka2,kka2_1:1,P00552,0.159158,NO,186,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.011,-3.942,2.931,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.520039,0.00409703,0.159158 kka2_1:4_F203A,kka2_1:4_203,Kka2,kka2_1:4,P00552,0.159176,NO,203,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-0.911,-3.329,2.418,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.168804,0.00318738,0.159176 beta-lactamase_156_A185Y,beta-lactamase_156_185,TEM-1,beta-lactamase_156,P62593,0.15922,NO,185,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.406,-4.227,2.821,,,H,A,0.46,-1.02,0.365,,65.03,HHP,-1.84033,0.111618,0.00467449,0.15922 kka2_1:1_L259T,kka2_1:1_259,Kka2,kka2_1:1,P00552,0.159261,NO,259,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.088,-2.444,1.356,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.520039,0.0206964,0.159261 kka2_1:2_V153H,kka2_1:2_153,Kka2,kka2_1:2,P00552,0.159286,NO,153,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.092,-4.991,3.899,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.295029,0.00501119,0.159286 beta-lactamase_2500_L167R,beta-lactamase_2500_167,TEM-1,beta-lactamase_2500,P62593,0.159315,NO,167,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.138,-2.876,1.738,,0.015,G,A,0.55,-0.63,7.813,,64.69,AHP,-1.30767,0.361275,0.00303566,0.159315 beta-lactamase_2500_N130Q,beta-lactamase_2500_130,TEM-1,beta-lactamase_2500,P62593,0.15932,NO,130,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-0.798,-3.674,2.876,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.361275,0.000683376,0.15932 beta-lactamase_156_A132M,beta-lactamase_156_132,TEM-1,beta-lactamase_156,P62593,0.15933,NO,132,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.9,-4.473,3.573,,,H,A,0.46,-0.93,10.621,,64.69,PHH,-1.138,0.111618,0.000962524,0.15933 beta-lactamase_2500_V260H,beta-lactamase_2500_260,TEM-1,beta-lactamase_2500,P62593,0.159337,NO,260,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.361275,0.00471757,0.159337 beta-lactamase_2500_G249Y,beta-lactamase_2500_249,TEM-1,beta-lactamase_2500,P62593,0.159366,NO,249,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.312,,,,0.256,S,B,0.23,0.04,30.841,30.841,72.73,HOO,-1.81367,0.361275,0.00220169,0.159366 beta-lactamase_625_I229G,beta-lactamase_625_229,TEM-1,beta-lactamase_625,P62593,0.159377,NO,229,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.267,-3.782,2.515,,0.083,E,B,0.48,-0.76,1.69,,50,HHH,-1.58767,0.213352,0.00477249,0.159377 beta-lactamase_V72Y,beta-lactamase_72,TEM-1,beta-lactamase,P62593,0.159511,NO,72,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.658,-4.055,2.397,5.80324,,H,A,2.78,-1.03,2.964,,65.73,BHH,-1.32167,0.221079,0.00501194,0.159511 kka2_1:4_W236I,kka2_1:4_236,Kka2,kka2_1:4,P00552,0.159552,NO,236,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-1.363,-3.761,2.398,,0.303,H,A,0.47,-0.76,2.277,,48.48,AHH,-1.81267,0.168804,0.0088796,0.159552 beta-lactamase_625_Y95D,beta-lactamase_625_95,TEM-1,beta-lactamase_625,P62593,0.159601,NO,95,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-1.715,-4.078,2.363,,0.122,,b,0.21,-0.37,3.355,,77.62,BHP,-2.16167,0.213352,0.00479449,0.159601 beta-lactamase_2500_C75F,beta-lactamase_2500_75,TEM-1,beta-lactamase_2500,P62593,0.159622,NO,75,C,F,CF,Special,Hydrophobic,5.07,3.32051,-1.74949,205,121,165,44,108.5,189.9,81.4,-1.245,-4.17,2.925,,,H,A,0.46,-0.87,0.844,,50,HOO,-1.24333,0.361275,0.0034616,0.159622 kka2_1:1_G189Q,kka2_1:1_189,Kka2,kka2_1:1,P00552,0.159637,NO,189,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.596,-4.153,3.557,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.520039,0.00253688,0.159637 beta-lactamase_625_I277K,beta-lactamase_625_277,TEM-1,beta-lactamase_625,P62593,0.159672,NO,277,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.213352,0.0169305,0.159672 kka2_1:1_Y218R,kka2_1:1_218,Kka2,kka2_1:1,P00552,0.159708,NO,218,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-1.438,-3.984,2.546,,0.122,H,A,1.25,-0.69,3.059,,56.06,BHP,-1.17533,0.520039,0.0126098,0.159708 beta-lactamase_39_S128R,beta-lactamase_39_128,TEM-1,beta-lactamase_39,P62593,0.15973,NO,128,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-0.84,-3.708,2.868,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.0495842,0.00071483,0.15973 kka2_1:2_N195P,kka2_1:2_195,Kka2,kka2_1:2,P00552,0.159741,NO,195,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-0.836,-3.906,3.07,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.295029,0.00276134,0.159741 kka2_1:4_D220V,kka2_1:4_220,Kka2,kka2_1:4,P00552,0.159741,NO,220,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.787,-2.698,1.911,,,H,A,0.75,-1.14,1.237,,46.59,PAH,-1.152,0.168804,0.00158066,0.159741 WW_domain_P202A,WW_domain_202,Yap65,WW_domain,P46937,0.159779,NO,202,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.4,-2.799,1.399,5.64207,,,,,,17.28,17.28,78.57,AOB,-1.436,0.153962,0.00212903,0.159779 kka2_1:4_G233E,kka2_1:4_233,Kka2,kka2_1:4,P00552,0.159801,NO,233,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.748,-3.501,2.753,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.168804,0.00232366,0.159801 beta-lactamase_2500_L47P,beta-lactamase_2500_47,TEM-1,beta-lactamase_2500,P62593,0.159826,NO,47,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.876,-4.153,2.277,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.361275,0.00439844,0.159826 beta-lactamase_156_A185E,beta-lactamase_156_185,TEM-1,beta-lactamase_156,P62593,0.159853,NO,185,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.406,-3.679,2.273,,,H,A,0.46,-1.02,0.365,,65.03,HHP,-1.84033,0.111618,0.00467449,0.159853 kka2_1:2_V153E,kka2_1:2_153,Kka2,kka2_1:2,P00552,0.159864,NO,153,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.092,-3.813,2.721,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.295029,0.00501119,0.159864 beta-lactamase_625_T69E,beta-lactamase_625_69,TEM-1,beta-lactamase_625,P62593,0.159884,NO,69,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-0.973,-3.476,2.503,,,G,A,0.22,-1.24,2.716,,93.01,PPH,-1.01833,0.213352,0.00127498,0.159884 kka2_1:1_A65Y,kka2_1:1_65,Kka2,kka2_1:1,P00552,0.159911,NO,65,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.744,-4.354,2.61,,0.437,H,A,0.46,-0.39,3.012,,63.64,HHB,-1.38733,0.520039,0.00709258,0.159911 kka2_1:1_D183K,kka2_1:1_183,Kka2,kka2_1:1,P00552,0.159959,NO,183,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.204,-3.416,2.212,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.520039,0.00426304,0.159959 kka2_1:2_L260A,kka2_1:2_260,Kka2,kka2_1:2,P00552,0.159974,NO,260,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.741,-3.106,2.365,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.295029,0.0233782,0.159974 beta-lactamase_625_I229Q,beta-lactamase_625_229,TEM-1,beta-lactamase_625,P62593,0.160012,NO,229,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.267,-4.304,3.037,,0.083,E,B,0.48,-0.76,1.69,,50,HHH,-1.58767,0.213352,0.00477249,0.160012 kka2_1:4_F203H,kka2_1:4_203,Kka2,kka2_1:4,P00552,0.160057,NO,203,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-0.911,-4.571,3.66,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.168804,0.00318738,0.160057 kka2_1:2_R38M,kka2_1:2_38,Kka2,kka2_1:2,P00552,0.160058,NO,38,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.207,-3.078,1.871,,0.355,E,B,1.2,-1.13,6.872,6.872,52.27,HBH,-1.28567,0.295029,0.00372499,0.160058 beta-lactamase_2500_L100D,beta-lactamase_2500_100,TEM-1,beta-lactamase_2500,P62593,0.160059,NO,100,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.218,-4.132,2.914,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.361275,0.00413885,0.160059 kka2_1:1_G74Q,kka2_1:1_74,Kka2,kka2_1:1,P00552,0.160069,NO,74,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.18,-3.052,1.872,,0.621,T,l,0.75,0.2,15.356,15.356,64.39,POH,-1.91667,0.520039,0.00587035,0.160069 beta-lactamase_2500_T107W,beta-lactamase_2500_107,TEM-1,beta-lactamase_2500,P62593,0.160129,NO,107,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.117,-5.223,4.106,,,G,A,0.22,-0.06,2.686,,67.83,HPA,-1.265,0.361275,0.00239347,0.160129 kka2_1:4_I228H,kka2_1:4_228,Kka2,kka2_1:4,P00552,0.16019,NO,228,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.142,-5.006,3.864,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.168804,0.00458834,0.16019 kka2_1:4_A222M,kka2_1:4_222,Kka2,kka2_1:4,P00552,0.160198,NO,222,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.725,-4.508,3.783,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.168804,0.00207657,0.160198 beta-lactamase_39_A132Y,beta-lactamase_39_132,TEM-1,beta-lactamase_39,P62593,0.160201,NO,132,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.9,-4.186,3.286,,,H,A,0.46,-0.93,8.408,,64.69,PHH,-1.138,0.0495842,0.000962524,0.160201 beta-lactamase_625_M209E,beta-lactamase_625_209,TEM-1,beta-lactamase_625,P62593,0.160202,NO,209,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.442,-3.84,2.398,,,H,A,0.55,-0.97,1.167,,64.69,HHA,-1.52633,0.213352,0.00625021,0.160202 beta-lactamase_2500_S233N,beta-lactamase_2500_233,TEM-1,beta-lactamase_2500,P62593,0.160246,NO,233,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.886,-2.73,0.844,,0.016,E,B,0.27,-1.01,2.851,,77.62,BPO,-1.17267,0.361275,0.00311415,0.160246 kka2_1:1_F206M,kka2_1:1_206,Kka2,kka2_1:1,P00552,0.160246,NO,206,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.349,-3.155,1.806,,0.006,E,B,0.58,-1.21,0.978,,63.64,OHH,-1.04,0.520039,0.00936868,0.160246 beta-lactamase_156_G243F,beta-lactamase_156_243,TEM-1,beta-lactamase_156,P62593,0.160277,NO,243,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.532,,,,,E,B,0.77,-1.24,2.866,,50,BOH,-1.46867,0.111618,0.00464034,0.160277 beta-lactamase_625_Y262H,beta-lactamase_625_262,TEM-1,beta-lactamase_625,P62593,0.160279,NO,262,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.213352,0.00853516,0.160279 kka2_1:1_T187E,kka2_1:1_187,Kka2,kka2_1:1,P00552,0.160302,NO,187,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.273,-3.655,2.382,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.520039,0.00693073,0.160302 Pab1_S154D,Pab1_154,Pab1,Pab1,P04147,0.160302,NO,154,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.146,-3.061,1.915,,0.208,E,B,0.1,-0.75,,,,HPP,-1.408,0.175299,0.000319331,0.160302 beta-lactamase_625_E164G,beta-lactamase_625_164,TEM-1,beta-lactamase_625,P62593,0.160454,NO,164,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-0.948,-2.443,1.495,,0.011,T,B,1.04,-0.4,1.321,,64.69,HAO,-1.388,0.213352,0.00137286,0.160454 beta-lactamase_2500_L160D,beta-lactamase_2500_160,TEM-1,beta-lactamase_2500,P62593,0.160457,NO,160,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.977,-4.122,3.145,,0.022,,B,0.55,-0.6,0.895,,44.41,BHA,-0.936,0.361275,0.00193775,0.160457 kka2_1:2_F206H,kka2_1:2_206,Kka2,kka2_1:2,P00552,0.160594,NO,206,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.349,-4.415,3.066,,0.006,E,B,0.58,-1.21,0.978,,63.64,OHH,-1.04,0.295029,0.00936868,0.160594 beta-lactamase_625_L146N,beta-lactamase_625_146,TEM-1,beta-lactamase_625,P62593,0.160634,NO,146,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.462,-4.208,2.746,,0.007,H,A,0.55,-0.56,2.16,,64.69,AHP,-1.656,0.213352,0.00474542,0.160634 kka2_1:8_A78K,kka2_1:8_78,Kka2,kka2_1:8,P00552,0.160637,NO,78,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.744,-3.53,1.786,,0.078,,B,1.04,-0.53,1.251,,56.06,OHH,-1.863,0.100394,0.00457299,0.160637 kka2_1:8_A78K,kka2_1:8_78,Kka2,kka2_1:8,P00552,0.160637,NO,78,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.744,-3.53,1.786,,0.078,,B,1.04,-0.53,1.251,,56.06,OHH,-1.863,0.100394,0.00457299,0.160637 kka2_1:1_L184V,kka2_1:1_184,Kka2,kka2_1:1,P00552,0.160663,NO,184,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.496,-2.642,1.146,,0.489,E,B,0.55,-0.06,19.127,19.127,63.26,AHH,-1.24833,0.520039,0.00518742,0.160663 kka2_1:2_C192W,kka2_1:2_192,Kka2,kka2_1:2,P00552,0.160798,NO,192,C,W,CW,Special,Hydrophobic,5.07,5.89,0.82,215,121,204,83,108.5,227.8,119.3,-1.067,-5.111,4.044,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.295029,0.00485428,0.160798 beta-lactamase_39_A124P,beta-lactamase_39_124,TEM-1,beta-lactamase_39,P62593,0.16081,NO,124,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.181,-3.759,2.578,,,H,A,0.46,-0.9,1.367,,64.34,HHH,-1.152,0.0495842,0.00481399,0.16081 beta-lactamase_625_N274W,beta-lactamase_625_274,TEM-1,beta-lactamase_625,P62593,0.160824,NO,274,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.213352,0.0110418,0.160824 kka2_1:1_V186H,kka2_1:1_186,Kka2,kka2_1:1,P00552,0.160849,NO,186,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.011,-4.974,3.963,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.520039,0.00409703,0.160849 beta-lactamase_625_Y44S,beta-lactamase_625_44,TEM-1,beta-lactamase_625,P62593,0.16089,NO,44,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-2.547,-3.605,1.058,,,E,B,0.21,-0.45,2.371,,73.78,OHH,-1.86267,0.213352,0.00426364,0.16089 kka2_1:1_F240M,kka2_1:1_240,Kka2,kka2_1:1,P00552,0.160893,NO,240,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-0.911,-4.239,3.328,,,H,A,1.62,-1.21,5.798,,50.38,BHH,-1.67267,0.520039,0.00552543,0.160893 kka2_1:4_V198W,kka2_1:4_198,Kka2,kka2_1:4,P00552,0.160937,NO,198,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.719,-5.441,3.722,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.168804,0.00835002,0.160937 beta-lactamase_2500_L167N,beta-lactamase_2500_167,TEM-1,beta-lactamase_2500,P62593,0.160952,NO,167,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.138,-4.008,2.87,,0.015,G,A,0.55,-0.63,7.813,,64.69,AHP,-1.30767,0.361275,0.00303566,0.160952 PSD95pdz3_I341E,PSD95pdz3_341,PSD95pdz3,PSD95pdz3,P31016,0.160964,NO,341,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.63,-3.572,1.942,5.73946,,,,,10.3187,,,,HHH,-1.50033,0.0758425,0.000824087,0.160964 beta-lactamase_156_A185N,beta-lactamase_156_185,TEM-1,beta-lactamase_156,P62593,0.161012,NO,185,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.406,-4.005,2.599,,,H,A,0.46,-1.02,0.365,,65.03,HHP,-1.84033,0.111618,0.00467449,0.161012 beta-lactamase_2500_L205Y,beta-lactamase_2500_205,TEM-1,beta-lactamase_2500,P62593,0.161099,NO,205,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.922,-3.727,2.805,,,H,A,0.55,-0.46,0.831,,42.31,PHH,-1.57767,0.361275,0.00255802,0.161099 beta-lactamase_625_D161K,beta-lactamase_625_161,TEM-1,beta-lactamase_625,P62593,0.16111,NO,161,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.891,-3.426,2.535,,0.341,,A,0.75,-0.52,4.655,,61.19,HAB,-0.961333,0.213352,0.000897697,0.16111 beta-lactamase_2500_M209I,beta-lactamase_2500_209,TEM-1,beta-lactamase_2500,P62593,0.161115,NO,209,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.442,-3.121,1.679,,,H,A,0.55,-0.97,3.229,,64.69,HHA,-1.52633,0.361275,0.00625021,0.161115 kka2_1:4_F264A,kka2_1:4_264,Kka2,kka2_1:4,P00552,0.161182,NO,264,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.02,-3.385,2.365,,0.296,,?,1.62,0.02,1.93,,71.59,HHO,-0.9655,0.168804,,0.161182 beta-lactamase_T158L,beta-lactamase_158,TEM-1,beta-lactamase,P62593,0.161187,NO,158,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.116,-3.303,2.187,5.32011,0.036,,B,0.98,-0.85,2.755,,69.58,HPB,-1.269,0.221079,0.00341825,0.161187 kka2_1:2_D190I,kka2_1:2_190,Kka2,kka2_1:2,P00552,0.161211,NO,190,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.708,-4.039,3.331,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.295029,0.00247989,0.161211 kka2_1:1_L223F,kka2_1:1_223,Kka2,kka2_1:1,P00552,0.16123,NO,223,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.861,-3.69,2.829,,,H,A,0.55,-1.24,1.268,,50,HHH,-0.854333,0.520039,0.00253574,0.16123 beta-lactamase_625_G249F,beta-lactamase_625_249,TEM-1,beta-lactamase_625,P62593,0.161269,NO,249,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.213352,0.00220169,0.161269 Ubiquitin_I36Y,Ubiquitin_36,Uba1,Ubiquitin,P0CG48,0.16129,NO,36,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.477,-4.079,2.602,5.1035,0.203,,B,0.27,-0.22,1.552,,30.8,OHO,-1.30767,0.205827,0.000630555,0.16129 Ubiquitin_I3N,Ubiquitin_3,Uba1,Ubiquitin,P0CG48,0.16129,NO,3,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.402,-4.062,2.66,4.80819,,E,B,,-0.78,,,,PHH,-1.54533,0.205827,0.000836911,0.16129 Ubiquitin_K11W,Ubiquitin_11,Uba1,Ubiquitin,P0CG48,0.16129,NO,11,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.354,-5.371,4.017,5.16813,0.401,,B,2.81,0.84,0.335,,25.84,OBP,-1.346,0.205827,0.000535553,0.16129 Ubiquitin_V70P,Ubiquitin_70,Uba1,Ubiquitin,P0CG48,0.16129,NO,70,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.874,-4.043,2.169,5.29728,0.05,E,B,0.96,-0.97,2.363,,34.31,HHH,-1.65533,0.205827,0.00106871,0.16129 kka2_1:4_T187W,kka2_1:4_187,Kka2,kka2_1:4,P00552,0.161304,NO,187,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.273,-5.339,4.066,,0.007,E,B,0.22,-0.85,2.73,,52.27,HPB,-1.06567,0.168804,0.00693073,0.161304 beta-lactamase_625_A185E,beta-lactamase_625_185,TEM-1,beta-lactamase_625,P62593,0.161324,NO,185,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.406,-3.679,2.273,,,H,A,0.46,-1.02,0.365,,65.03,HHP,-1.84033,0.213352,0.00467449,0.161324 beta-lactamase_156_C121Y,beta-lactamase_156_121,TEM-1,beta-lactamase_156,P62593,0.161329,NO,121,C,Y,CY,Special,Hydrophobic,5.07,5.66,0.59,194,121,181,60,108.5,193.6,85.1,-0.953,-4.188,3.235,,,H,A,0.46,-0.81,1.136,,63.29,HOP,-1.46767,0.111618,0.000744322,0.161329 kka2_1:2_T187I,kka2_1:2_187,Kka2,kka2_1:2,P00552,0.161366,NO,187,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.273,-2.925,1.652,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.295029,0.00693073,0.161366 beta-lactamase_156_L79R,beta-lactamase_156_79,TEM-1,beta-lactamase_156,P62593,0.161389,NO,79,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.842,-3.93,3.088,,0.007,H,A,0.55,-0.16,1.831,,50.35,HHP,-1.44333,0.111618,0.000947397,0.161389 beta-lactamase_625_S68P,beta-lactamase_625_68,TEM-1,beta-lactamase_625,P62593,0.161398,NO,68,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-0.913,-3.704,2.791,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.213352,0.000800065,0.161398 kka2_1:2_V186D,kka2_1:2_186,Kka2,kka2_1:2,P00552,0.161404,NO,186,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.011,-4.046,3.035,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.295029,0.00409703,0.161404 beta-lactamase_2500_T158M,beta-lactamase_2500_158,TEM-1,beta-lactamase_2500,P62593,0.161431,NO,158,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.116,-4.575,3.459,,0.036,,B,0.22,-0.85,1.344,,69.58,HPB,-1.269,0.361275,0.00341825,0.161431 beta-lactamase_625_T107W,beta-lactamase_625_107,TEM-1,beta-lactamase_625,P62593,0.16155,NO,107,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.117,-5.223,4.106,,,G,A,0.22,-0.06,3.676,,67.83,HPA,-1.265,0.213352,0.00239347,0.16155 beta-lactamase_156_L146K,beta-lactamase_156_146,TEM-1,beta-lactamase_156,P62593,0.161592,NO,146,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.462,-3.867,2.405,,0.007,H,A,0.55,-0.56,1.578,,64.69,AHP,-1.656,0.111618,0.00474542,0.161592 beta-lactamase_2500_L192D,beta-lactamase_2500_192,TEM-1,beta-lactamase_2500,P62593,0.161595,NO,192,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.254,-4.104,2.85,,0.095,H,A,0.55,0.35,1.902,,60.14,HHP,-1.41833,0.361275,0.00558728,0.161595 beta-lactamase_2500_A124Q,beta-lactamase_2500_124,TEM-1,beta-lactamase_2500,P62593,0.161644,NO,124,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.181,-4.004,2.823,,,H,A,0.46,-0.9,0.314,,64.34,HHH,-1.152,0.361275,0.00481399,0.161644 kka2_1:4_A224W,kka2_1:4_224,Kka2,kka2_1:4,P00552,0.161657,NO,224,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.977,-5.377,4.4,,,H,A,0.46,-1.26,0.93,,63.64,HHP,-1.41033,0.168804,0.00352047,0.161657 kka2_1:8_A78H,kka2_1:8_78,Kka2,kka2_1:8,P00552,0.161694,NO,78,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.744,-4.753,3.009,,0.078,,B,1.04,-0.53,1.251,,56.06,OHH,-1.863,0.100394,0.00457299,0.161694 kka2_1:8_A78H,kka2_1:8_78,Kka2,kka2_1:8,P00552,0.161694,NO,78,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.744,-4.753,3.009,,0.078,,B,1.04,-0.53,1.251,,56.06,OHH,-1.863,0.100394,0.00457299,0.161694 beta-lactamase_2500_G243I,beta-lactamase_2500_243,TEM-1,beta-lactamase_2500,P62593,0.16171,NO,243,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.532,-3.58,2.048,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.361275,0.00464034,0.16171 kka2_1:1_A255K,kka2_1:1_255,Kka2,kka2_1:1,P00552,0.161728,NO,255,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.715,-2.818,1.103,,0.466,H,A,0.46,-0.52,0.946,,65.53,HHH,-1.71267,0.520039,0.0126809,0.161728 kka2_1:1_Q136Y,kka2_1:1_136,Kka2,kka2_1:1,P00552,0.161806,NO,136,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-3.021,-4.291,1.27,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.520039,0.00624149,0.161806 beta-lactamase_625_L47P,beta-lactamase_625_47,TEM-1,beta-lactamase_625,P62593,0.16182,NO,47,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.876,-4.153,2.277,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.213352,0.00439844,0.16182 beta-lactamase_625_F228D,beta-lactamase_625_228,TEM-1,beta-lactamase_625,P62593,0.161824,NO,228,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-2.342,-3.807,1.465,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.213352,0.0046669,0.161824 kka2_1:2_A222P,kka2_1:2_222,Kka2,kka2_1:2,P00552,0.161843,NO,222,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.725,-3.683,2.958,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.295029,0.00207657,0.161843 kka2_1:4_A78Y,kka2_1:4_78,Kka2,kka2_1:4,P00552,0.161843,NO,78,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.744,-4.391,2.647,,0.078,.,B,0.46,-0.53,0.594,,56.06,OHH,-1.863,0.168804,0.00457299,0.161843 beta-lactamase_2500_T178M,beta-lactamase_2500_178,TEM-1,beta-lactamase_2500,P62593,0.161881,NO,178,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-0.791,-4.48,3.689,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.361275,0.000684366,0.161881 beta-lactamase_156_T158R,beta-lactamase_156_158,TEM-1,beta-lactamase_156,P62593,0.161889,NO,158,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.116,-3.803,2.687,,0.036,,B,0.22,-0.85,3.771,,69.58,HPB,-1.269,0.111618,0.00341825,0.161889 beta-lactamase_2500_Y44H,beta-lactamase_2500_44,TEM-1,beta-lactamase_2500,P62593,0.16193,NO,44,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-2.547,-4.769,2.222,,,E,B,0.21,-0.45,2.184,,73.78,OHH,-1.86267,0.361275,0.00426364,0.16193 kka2_1:1_A117P,kka2_1:1_117,Kka2,kka2_1:1,P00552,0.161942,NO,117,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.828,-3.747,2.919,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.520039,0.00282984,0.161942 beta-lactamase_156_A124E,beta-lactamase_156_124,TEM-1,beta-lactamase_156,P62593,0.161955,NO,124,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.181,-3.544,2.363,,,H,A,0.46,-0.9,2.027,,64.34,HHH,-1.152,0.111618,0.00481399,0.161955 beta-lactamase_156_E164F,beta-lactamase_156_164,TEM-1,beta-lactamase_156,P62593,0.161972,NO,164,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-0.948,-4.341,3.393,,0.011,T,B,1.04,-0.4,3.445,,64.69,HAO,-1.388,0.111618,0.00137286,0.161972 beta-lactamase_625_G249M,beta-lactamase_625_249,TEM-1,beta-lactamase_625,P62593,0.162019,NO,249,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.213352,0.00220169,0.162019 kka2_1:1_N195I,kka2_1:1_195,Kka2,kka2_1:1,P00552,0.162024,NO,195,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-0.836,-4.062,3.226,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.520039,0.00276134,0.162024 kka2_1:2_L102H,kka2_1:2_102,Kka2,kka2_1:2,P00552,0.162057,NO,102,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.804,-4.931,4.127,,,T,A,1.59,-1.17,4.258,,42.42,AHH,-1.398,0.295029,0.00201332,0.162057 kka2_1:2_G233N,kka2_1:2_233,Kka2,kka2_1:2,P00552,0.16206,NO,233,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.748,-3.476,2.728,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.295029,0.00232366,0.16206 beta-lactamase_39_S128L,beta-lactamase_39_128,TEM-1,beta-lactamase_39,P62593,0.162068,NO,128,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-0.84,-3.358,2.518,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.0495842,0.00071483,0.162068 beta-lactamase_0_V117L,beta-lactamase_0_117,TEM-1,beta-lactamase_0,P62593,0.162089,NO,117,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.53,-1.606,0.076,,,H,A,0.44,-0.34,1.16,,65.03,PHB,-1.741,0.0500837,0.00467906,0.162089 kka2_1:2_A78D,kka2_1:2_78,Kka2,kka2_1:2,P00552,0.162167,NO,78,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.744,-3.601,1.857,,0.078,.,B,0.46,-0.53,0.206,,56.06,OHH,-1.863,0.295029,0.00457299,0.162167 kka2_1:1_R140W,kka2_1:1_140,Kka2,kka2_1:1,P00552,0.162196,NO,140,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.351,-5.43,4.079,,0.12,H,A,1.2,0.2,11.345,11.345,53.03,BBH,-1.885,0.520039,0.00430167,0.162196 beta-lactamase_2500_M209P,beta-lactamase_2500_209,TEM-1,beta-lactamase_2500,P62593,0.162266,NO,209,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.442,-4.077,2.635,,,H,A,0.55,-0.97,3.229,,64.69,HHA,-1.52633,0.361275,0.00625021,0.162266 beta-lactamase_625_T158R,beta-lactamase_625_158,TEM-1,beta-lactamase_625,P62593,0.162289,NO,158,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.116,-3.803,2.687,,0.036,,B,0.22,-0.85,3.771,,69.58,HPB,-1.269,0.213352,0.00341825,0.162289 beta-lactamase_2500_N134I,beta-lactamase_2500_134,TEM-1,beta-lactamase_2500,P62593,0.162389,NO,134,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-0.879,-4.036,3.157,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.361275,0.000644786,0.162389 beta-lactamase_2500_L192P,beta-lactamase_2500_192,TEM-1,beta-lactamase_2500,P62593,0.162392,NO,192,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.254,-4.129,2.875,,0.095,H,A,0.55,0.35,1.902,,60.14,HHP,-1.41833,0.361275,0.00558728,0.162392 beta-lactamase_625_L205N,beta-lactamase_625_205,TEM-1,beta-lactamase_625,P62593,0.162414,NO,205,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.922,-4.141,3.219,,,H,A,0.55,-0.46,3.782,,42.31,PHH,-1.57767,0.213352,0.00255802,0.162414 beta-lactamase_2500_G249V,beta-lactamase_2500_249,TEM-1,beta-lactamase_2500,P62593,0.162428,NO,249,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.312,,,,0.256,S,B,0.23,0.04,30.841,30.841,72.73,HOO,-1.81367,0.361275,0.00220169,0.162428 kka2_1:2_W236P,kka2_1:2_236,Kka2,kka2_1:2,P00552,0.162429,NO,236,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-1.363,-4.32,2.957,,0.303,H,A,1.51,-0.76,5.58,,48.48,AHH,-1.81267,0.295029,0.0088796,0.162429 beta-lactamase_625_V82P,beta-lactamase_625_82,TEM-1,beta-lactamase_625,P62593,0.162453,NO,82,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.325,-4.008,2.683,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.213352,0.00397046,0.162453 beta-lactamase_625_D129Q,beta-lactamase_625_129,TEM-1,beta-lactamase_625,P62593,0.162496,NO,129,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.816,-3.637,2.821,,,,B,0.75,-0.69,0.171,,34.97,PAP,-0.818,0.213352,0.00109178,0.162496 kka2_1:2_C77E,kka2_1:2_77,Kka2,kka2_1:2,P00552,0.162521,NO,77,C,E,CE,Special,negativeCharge,5.07,3.22,-1.85,170,121,147,26,108.5,138.4,29.9,-1.477,-3.891,2.414,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.295029,0.00441216,0.162521 PSD95pdz3_H372A,PSD95pdz3_372,PSD95pdz3,PSD95pdz3,P31016,0.162522,NO,372,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-1.627,-2.984,1.357,5.5607,,,,,17.008,,,,PBA,-1.63033,0.0758425,0.00040301,0.162522 kka2_1:8_D220Q,kka2_1:8_220,Kka2,kka2_1:8,P00552,0.162538,NO,220,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.787,-3.763,2.976,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.100394,0.00158066,0.162538 kka2_1:8_D220Q,kka2_1:8_220,Kka2,kka2_1:8,P00552,0.162538,NO,220,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.787,-3.763,2.976,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.100394,0.00158066,0.162538 beta-lactamase_L136Q,beta-lactamase_136,TEM-1,beta-lactamase,P62593,0.162564,NO,136,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.232,-4.242,3.01,5.31114,,H,A,2.89,-0.34,1.539,,48.95,HHH,-1.088,0.221079,0.00442304,0.162564 beta-lactamase_625_L160W,beta-lactamase_625_160,TEM-1,beta-lactamase_625,P62593,0.162639,NO,160,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.977,-5.194,4.217,,0.022,,B,0.55,-0.6,0.237,,44.41,BHA,-0.936,0.213352,0.00193775,0.162639 kka2_1:1_D216I,kka2_1:1_216,Kka2,kka2_1:1,P00552,0.162665,NO,216,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.785,-4.062,3.277,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.520039,0.00229969,0.162665 kka2_1:1_F263M,kka2_1:1_263,Kka2,kka2_1:1,P00552,0.162688,NO,263,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-0.911,-4.239,3.328,,0.006,G,A,0.58,-0.12,2.284,,45.83,AHH,-0.92,0.520039,0.0172454,0.162688 kka2_1:4_V186S,kka2_1:4_186,Kka2,kka2_1:4,P00552,0.162698,NO,186,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.011,-3.722,2.711,,,E,B,0.44,-0.61,0.679,,45.83,HHP,-1.10967,0.168804,0.00409703,0.162698 beta-lactamase_2500_T158R,beta-lactamase_2500_158,TEM-1,beta-lactamase_2500,P62593,0.162729,NO,158,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.116,-3.803,2.687,,0.036,,B,0.22,-0.85,1.344,,69.58,HPB,-1.269,0.361275,0.00341825,0.162729 beta-lactamase_2500_L192E,beta-lactamase_2500_192,TEM-1,beta-lactamase_2500,P62593,0.162737,NO,192,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.254,-3.893,2.639,,0.095,H,A,0.55,0.35,1.902,,60.14,HHP,-1.41833,0.361275,0.00558728,0.162737 kka2_1:4_W236E,kka2_1:4_236,Kka2,kka2_1:4,P00552,0.162748,NO,236,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-1.363,-3.989,2.626,,0.303,H,A,0.47,-0.76,2.277,,48.48,AHH,-1.81267,0.168804,0.0088796,0.162748 beta-lactamase_156_W227R,beta-lactamase_156_227,TEM-1,beta-lactamase_156,P62593,0.162763,NO,227,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-0.982,-4.182,3.2,,0.272,,B,0.47,-0.29,2.533,,74.48,OHH,-1.595,0.111618,0.00226019,0.162763 kka2_1:1_R211T,kka2_1:1_211,Kka2,kka2_1:1,P00552,0.162823,NO,211,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-0.899,-3.493,2.594,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.520039,0.00204888,0.162823 beta-lactamase_625_D174Y,beta-lactamase_625_174,TEM-1,beta-lactamase_625,P62593,0.162921,NO,174,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.738,-4.387,3.649,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.213352,0.00125633,0.162921 beta-lactamase_39_L74W,beta-lactamase_39_74,TEM-1,beta-lactamase_39,P62593,0.162945,NO,74,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.296,-5.261,3.965,,,H,A,0.55,-0.91,1.581,,50,HHO,-1.34933,0.0495842,0.00493255,0.162945 kka2_1:1_Y257R,kka2_1:1_257,Kka2,kka2_1:1,P00552,0.162946,NO,257,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-1.064,-4.088,3.024,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.520039,0.0148191,0.162946 kka2_1:4_D208E,kka2_1:4_208,Kka2,kka2_1:4,P00552,0.162949,NO,208,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.708,-2.793,2.085,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.168804,0.00212588,0.162949 beta-lactamase_156_L205G,beta-lactamase_156_205,TEM-1,beta-lactamase_156,P62593,0.162956,NO,205,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.922,-3.783,2.861,,,H,A,0.55,-0.46,0.678,,42.31,PHH,-1.57767,0.111618,0.00255802,0.162956 beta-lactamase_T107D,beta-lactamase_107,TEM-1,beta-lactamase,P62593,0.163002,NO,107,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.117,-3.478,2.361,5.23432,,G,A,2.12,-0.06,3.676,,67.83,HPA,-1.265,0.221079,0.00239347,0.163002 beta-lactamase_156_W227L,beta-lactamase_156_227,TEM-1,beta-lactamase_156,P62593,0.163052,NO,227,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-0.982,-3.387,2.405,,0.272,,B,0.47,-0.29,2.533,,74.48,OHH,-1.595,0.111618,0.00226019,0.163052 beta-lactamase_2500_W208R,beta-lactamase_2500_208,TEM-1,beta-lactamase_2500,P62593,0.163052,NO,208,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-0.818,-4.158,3.34,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.361275,0.00126609,0.163052 kka2_1:2_A224W,kka2_1:2_224,Kka2,kka2_1:2,P00552,0.163055,NO,224,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.977,-5.377,4.4,,,H,A,0.46,-1.26,1.646,,63.64,HHP,-1.41033,0.295029,0.00352047,0.163055 kka2_1:4_V113Q,kka2_1:4_113,Kka2,kka2_1:4,P00552,0.163086,NO,113,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.233,-4.296,3.063,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.168804,0.00650191,0.163086 beta-lactamase_2500_I93P,beta-lactamase_2500_93,TEM-1,beta-lactamase_2500,P62593,0.163161,NO,93,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.401,-2.926,1.525,,0.128,E,B,0.48,0.44,19.374,19.374,67.83,BHB,-1.873,0.361275,0.00527066,0.163161 beta-lactamase_625_N130L,beta-lactamase_625_130,TEM-1,beta-lactamase_625,P62593,0.163168,NO,130,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-0.798,-3.583,2.785,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.213352,0.000683376,0.163168 beta-lactamase_625_Y44G,beta-lactamase_625_44,TEM-1,beta-lactamase_625,P62593,0.16321,NO,44,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-2.547,-3.687,1.14,,,E,B,0.21,-0.45,2.371,,73.78,OHH,-1.86267,0.213352,0.00426364,0.16321 beta-lactamase_2500_D129F,beta-lactamase_2500_129,TEM-1,beta-lactamase_2500,P62593,0.163305,NO,129,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.816,-4.318,3.502,,,,B,0.75,-0.69,1.29,,34.97,PAP,-0.818,0.361275,0.00109178,0.163305 kka2_1:2_C192N,kka2_1:2_192,Kka2,kka2_1:2,P00552,0.163348,NO,192,C,N,CN,Special,Polar,5.07,5.47157,0.401575,139,121,132,11,108.5,114.1,5.6,-1.067,-3.983,2.916,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.295029,0.00485428,0.163348 beta-lactamase_2500_G249Q,beta-lactamase_2500_249,TEM-1,beta-lactamase_2500,P62593,0.163362,NO,249,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.312,,,,0.256,S,B,0.23,0.04,30.841,30.841,72.73,HOO,-1.81367,0.361275,0.00220169,0.163362 beta-lactamase_2500_T158E,beta-lactamase_2500_158,TEM-1,beta-lactamase_2500,P62593,0.163397,NO,158,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.116,-3.449,2.333,,0.036,,B,0.22,-0.85,1.344,,69.58,HPB,-1.269,0.361275,0.00341825,0.163397 kka2_1:2_A34F,kka2_1:2_34,Kka2,kka2_1:2,P00552,0.163402,NO,34,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.928,-4.127,3.199,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.295029,0.00343484,0.163402 beta-lactamase_156_D155L,beta-lactamase_156_155,TEM-1,beta-lactamase_156,P62593,0.163482,NO,155,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.889,-3.807,2.918,,0.049,,B,0.75,-0.9,0.315,,64.69,OAB,-1.62267,0.111618,0.00135315,0.163482 beta-lactamase_2500_A124R,beta-lactamase_2500_124,TEM-1,beta-lactamase_2500,P62593,0.163482,NO,124,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.181,-3.827,2.646,,,H,A,0.46,-0.9,0.314,,64.34,HHH,-1.152,0.361275,0.00481399,0.163482 beta-lactamase_156_D177R,beta-lactamase_156_177,TEM-1,beta-lactamase_156,P62593,0.163485,NO,177,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.967,-3.931,2.964,,0.006,T,L,0.75,-1.02,2.072,,64.69,BAP,-0.873667,0.111618,0.000864022,0.163485 kka2_1:1_G55K,kka2_1:1_55,Kka2,kka2_1:1,P00552,0.163544,NO,55,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.625,-3.726,2.101,,0.517,S,b,0.29,1.19,4.035,,63.64,POH,-2.05967,0.520039,0.00667877,0.163544 kka2_1:1_H106L,kka2_1:1_106,Kka2,kka2_1:1,P00552,0.163596,NO,106,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-3.13,-2.804,-0.326,,1.065,.,a,0.17,-0.95,2.53,,71.59,PBH,-2.10433,0.520039,0.00730778,0.163596 beta-lactamase_2500_R257E,beta-lactamase_2500_257,TEM-1,beta-lactamase_2500,P62593,0.163597,NO,257,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.361275,0.00756629,0.163597 kka2_1:1_P76E,kka2_1:1_76,Kka2,kka2_1:1,P00552,0.1636,NO,76,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.449,-2.905,1.456,,0.331,.,B,0.52,-0.41,0.345,,63.64,HOO,-1.662,0.520039,0.00625685,0.1636 beta-lactamase_2500_T107K,beta-lactamase_2500_107,TEM-1,beta-lactamase_2500,P62593,0.163625,NO,107,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.117,-3.447,2.33,,,G,A,0.22,-0.06,2.686,,67.83,HPA,-1.265,0.361275,0.00239347,0.163625 beta-lactamase_156_F70D,beta-lactamase_156_70,TEM-1,beta-lactamase_156,P62593,0.163646,NO,70,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.169,-3.91,2.741,,,H,A,0.58,-1.34,1.918,,63.99,PHB,-0.980667,0.111618,0.00193499,0.163646 beta-lactamase_2500_E164F,beta-lactamase_2500_164,TEM-1,beta-lactamase_2500,P62593,0.163692,NO,164,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-0.948,-4.341,3.393,,0.011,T,B,1.04,-0.4,0.352,,64.69,HAO,-1.388,0.361275,0.00137286,0.163692 beta-lactamase_2500_L136F,beta-lactamase_2500_136,TEM-1,beta-lactamase_2500,P62593,0.16373,NO,136,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.232,-3.77,2.538,,,H,A,0.55,-0.34,1.36,,48.95,HHH,-1.088,0.361275,0.00442304,0.16373 beta-lactamase_156_L191P,beta-lactamase_156_191,TEM-1,beta-lactamase_156,P62593,0.163744,NO,191,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.087,-4.09,3.003,,,H,A,0.55,0.09,1.372,,63.29,BHH,-1.445,0.111618,0.00263549,0.163744 beta-lactamase_625_S128L,beta-lactamase_625_128,TEM-1,beta-lactamase_625,P62593,0.163763,NO,128,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-0.84,-3.358,2.518,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.213352,0.00071483,0.163763 kka2_1:1_M116P,kka2_1:1_116,Kka2,kka2_1:1,P00552,0.163828,NO,116,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-2.482,-4.193,1.711,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.520039,0.00745147,0.163828 kka2_1:2_D183K,kka2_1:2_183,Kka2,kka2_1:2,P00552,0.16384,NO,183,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.204,-3.416,2.212,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.295029,0.00426304,0.16384 beta-lactamase_P65D,beta-lactamase_65,TEM-1,beta-lactamase,P62593,0.163844,NO,65,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.894,-3.578,2.684,5.59094,0.098,E,B,0.23,-0.62,0.623,,40.56,HOH,-1.03233,0.221079,0.00152776,0.163844 beta-lactamase_2500_M115P,beta-lactamase_2500_115,TEM-1,beta-lactamase_2500,P62593,0.163897,NO,115,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.389,-4.034,2.645,,0.019,E,B,0.55,0.08,3.261,,69.58,OHP,-1.25433,0.361275,0.0034337,0.163897 kka2_1:1_R217W,kka2_1:1_217,Kka2,kka2_1:1,P00552,0.163907,NO,217,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.158,-5.446,4.288,,0.252,T,A,1.2,-0.59,0.381,,52.27,ABH,-1.127,0.520039,0.0047191,0.163907 kka2_1:4_E63H,kka2_1:4_63,Kka2,kka2_1:4,P00552,0.163929,NO,63,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-0.762,-4.258,3.496,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.168804,0.00118399,0.163929 beta-lactamase_39_K71C,beta-lactamase_39_71,TEM-1,beta-lactamase_39,P62593,0.163963,NO,71,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-0.8,-5.087,4.287,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.0495842,0.00103192,0.163963 beta-lactamase_156_G43V,beta-lactamase_156_43,TEM-1,beta-lactamase_156,P62593,0.163973,NO,43,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.62,-3.754,3.134,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.111618,0.00120151,0.163973 beta-lactamase_M1N,beta-lactamase_1,TEM-1,beta-lactamase,P62593,0.163979,NO,1,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.998,-3.58,1.582,,,,,,,,,,OHP,-1.97,0.221079,0.00162771,0.163979 Pab1_I137G,Pab1_137,Pab1,Pab1,P04147,0.164001,NO,137,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.212,-3.625,2.413,,0.068,,B,0.77,0.35,,,,AHA,-1.314,0.175299,0.000342224,0.164001 beta-lactamase_625_N134W,beta-lactamase_625_134,TEM-1,beta-lactamase_625,P62593,0.164074,NO,134,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-0.879,-5.545,4.666,,0.138,H,A,0.61,-0.6,3.776,,53.15,HPH,-1.02233,0.213352,0.000644786,0.164074 beta-lactamase_2500_P65G,beta-lactamase_2500_65,TEM-1,beta-lactamase_2500,P62593,0.164114,NO,65,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.894,-3.443,2.549,,0.098,E,B,0.52,-0.62,0.3,,40.56,HOH,-1.03233,0.361275,0.00152776,0.164114 beta-lactamase_156_D129W,beta-lactamase_156_129,TEM-1,beta-lactamase_156,P62593,0.16413,NO,129,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.816,-5.545,4.729,,,,B,0.75,-0.69,1.924,,34.97,PAP,-0.818,0.111618,0.00109178,0.16413 hsp90_W585K,hsp90_585,hsp90,hsp90,P02829,0.164137,NO,585,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-4.251,-2.835,0,5.31455,0.508,,B,1.22,0.43,,,,OHP,-3.17533,0.368192,0.000222939,0.164137 kka2_1:4_M197H,kka2_1:4_197,Kka2,kka2_1:4,P00552,0.164152,NO,197,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.707,-4.99,3.283,,0.121,E,B,0.55,-1.19,0.415,,65.53,HHH,-1.847,0.168804,0.00921295,0.164152 beta-lactamase_T131D,beta-lactamase_131,TEM-1,beta-lactamase,P62593,0.164165,NO,131,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.328,-3.605,2.277,5.0548,,H,A,0.53,-0.69,3.306,,67.48,PPH,-1.00867,0.221079,0.00345886,0.164165 kka2_1:8_R226F,kka2_1:8_226,Kka2,kka2_1:8,P00552,0.164218,NO,226,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.392,-4.163,2.771,,0.222,H,A,0.16,-0.71,3.818,,56.06,PBA,-1.84767,0.100394,0.0108032,0.164218 kka2_1:8_R226F,kka2_1:8_226,Kka2,kka2_1:8,P00552,0.164218,NO,226,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.392,-4.163,2.771,,0.222,H,A,0.16,-0.71,3.818,,56.06,PBA,-1.84767,0.100394,0.0108032,0.164218 beta-lactamase_625_A246P,beta-lactamase_625_246,TEM-1,beta-lactamase_625,P62593,0.164259,NO,246,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.121,-4.126,2.005,,0.01,E,B,0.46,-1.01,1.201,,73.78,HHH,-1.55633,0.213352,0.00569458,0.164259 kka2_1:1_P98H,kka2_1:1_98,Kka2,kka2_1:1,P00552,0.16426,NO,98,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.526,-4.763,3.237,,0.391,S,B,0.52,-0.65,1.521,,63.26,HOO,-1.19167,0.520039,0.00622754,0.16426 beta-lactamase_2500_R59T,beta-lactamase_2500_59,TEM-1,beta-lactamase_2500,P62593,0.164377,NO,59,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.345,-3.487,2.142,,0.329,S,L,1.2,-0.09,3.719,,73.08,HBO,-2.24267,0.361275,0.00318082,0.164377 kka2_1:1_R44D,kka2_1:1_44,Kka2,kka2_1:1,P00552,0.164426,NO,44,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.062,-3.066,1.004,,0.487,S,B,1.2,-0.35,2.717,,71.59,OBO,-1.80767,0.520039,0.00745043,0.164426 kka2_1:8_I221R,kka2_1:8_221,Kka2,kka2_1:8,P00552,0.164428,NO,221,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.739,-4.17,2.431,,,H,A,1.52,-1.15,1.599,,71.59,AHH,-1.08367,0.100394,0.00945908,0.164428 kka2_1:8_I221R,kka2_1:8_221,Kka2,kka2_1:8,P00552,0.164428,NO,221,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.739,-4.17,2.431,,,H,A,1.52,-1.15,1.599,,71.59,AHH,-1.08367,0.100394,0.00945908,0.164428 beta-lactamase_2500_E61P,beta-lactamase_2500_61,TEM-1,beta-lactamase_2500,P62593,0.16447,NO,61,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.115,-3.861,1.746,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.361275,0.00440955,0.16447 beta-lactamase_156_D177Q,beta-lactamase_156_177,TEM-1,beta-lactamase_156,P62593,0.164518,NO,177,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.967,-3.799,2.832,,0.006,T,L,0.75,-1.02,2.072,,64.69,BAP,-0.873667,0.111618,0.000864022,0.164518 beta-lactamase_2500_A124Y,beta-lactamase_2500_124,TEM-1,beta-lactamase_2500,P62593,0.164542,NO,124,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.181,-4.228,3.047,,,H,A,0.46,-0.9,0.314,,64.34,HHH,-1.152,0.361275,0.00481399,0.164542 beta-lactamase_2500_L146D,beta-lactamase_2500_146,TEM-1,beta-lactamase_2500,P62593,0.164551,NO,146,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.462,-4.108,2.646,,0.007,H,A,0.55,-0.56,1.578,,64.69,AHP,-1.656,0.361275,0.00474542,0.164551 kka2_1:2_R66A,kka2_1:2_66,Kka2,kka2_1:2,P00552,0.164667,NO,66,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-0.922,-3.14,2.218,,0.103,H,A,1.2,-0.2,2.659,,46.21,HBH,-1.13567,0.295029,0.00161025,0.164667 beta-lactamase_2500_A132K,beta-lactamase_2500_132,TEM-1,beta-lactamase_2500,P62593,0.16469,NO,132,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.9,-3.501,2.601,,,H,A,0.46,-0.93,8.408,,64.69,PHH,-1.138,0.361275,0.000962524,0.16469 beta-lactamase_2500_I125E,beta-lactamase_2500_125,TEM-1,beta-lactamase_2500,P62593,0.164717,NO,125,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.441,-3.878,2.437,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.361275,0.00383964,0.164717 kka2_1:1_L94F,kka2_1:1_94,Kka2,kka2_1:1,P00552,0.164839,NO,94,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.618,-3.805,2.187,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.520039,0.00520888,0.164839 kka2_1:2_G210P,kka2_1:2_210,Kka2,kka2_1:2,P00552,0.164891,NO,210,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.095,-3.953,2.858,,0.103,T,A,0.29,-0.62,0.271,,50,OOB,-0.966667,0.295029,0.00598378,0.164891 kka2_1:2_L259G,kka2_1:2_259,Kka2,kka2_1:2,P00552,0.165009,NO,259,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.088,-3.711,2.623,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.295029,0.0206964,0.165009 beta-lactamase_625_I261R,beta-lactamase_625_261,TEM-1,beta-lactamase_625,P62593,0.165028,NO,261,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.213352,0.0123091,0.165028 kka2_1:1_V186K,kka2_1:1_186,Kka2,kka2_1:1,P00552,0.165092,NO,186,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.011,-3.841,2.83,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.520039,0.00409703,0.165092 kka2_1:4_I254P,kka2_1:4_254,Kka2,kka2_1:4,P00552,0.165098,NO,254,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.933,-4.189,2.256,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.168804,0.0132375,0.165098 beta-lactamase_156_V259K,beta-lactamase_156_259,TEM-1,beta-lactamase_156,P62593,0.165104,NO,259,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.111618,0.0070773,0.165104 beta-lactamase_625_A246N,beta-lactamase_625_246,TEM-1,beta-lactamase_625,P62593,0.165122,NO,246,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.121,-4.23,2.109,,0.01,E,B,0.46,-1.01,1.201,,73.78,HHH,-1.55633,0.213352,0.00569458,0.165122 kka2_1:1_I115C,kka2_1:1_115,Kka2,kka2_1:1,P00552,0.165179,NO,115,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.606,-4.846,3.24,,0.105,H,A,0.48,-1.18,0.878,,65.53,PHH,-2.205,0.520039,0.00836567,0.165179 kka2_1:1_M116Q,kka2_1:1_116,Kka2,kka2_1:1,P00552,0.165184,NO,116,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-2.482,-4.256,1.774,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.520039,0.00745147,0.165184 beta-lactamase_D177H,beta-lactamase_177,TEM-1,beta-lactamase,P62593,0.165192,NO,177,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.967,-4.511,3.544,5.08038,0.006,T,L,1.59,-1.02,3.536,,64.69,BAP,-0.873667,0.221079,0.000864022,0.165192 kka2_1:2_M197H,kka2_1:2_197,Kka2,kka2_1:2,P00552,0.1652,NO,197,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.707,-4.99,3.283,,0.121,E,B,0.55,-1.19,2.097,,65.53,HHH,-1.847,0.295029,0.00921295,0.1652 kka2_1:8_G205Y,kka2_1:8_205,Kka2,kka2_1:8,P00552,0.165264,NO,205,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.596,-4.416,3.82,,,E,b,0.75,-1.05,,,,POH,-1.09933,0.100394,0.00221855,0.165264 kka2_1:8_G205Y,kka2_1:8_205,Kka2,kka2_1:8,P00552,0.165264,NO,205,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.596,-4.416,3.82,,,E,b,0.75,-1.05,,,,POH,-1.09933,0.100394,0.00221855,0.165264 beta-lactamase_156_A132F,beta-lactamase_156_132,TEM-1,beta-lactamase_156,P62593,0.165281,NO,132,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.9,-4.091,3.191,,,H,A,0.46,-0.93,10.621,,64.69,PHH,-1.138,0.111618,0.000962524,0.165281 kka2_1:4_V198K,kka2_1:4_198,Kka2,kka2_1:4,P00552,0.165342,NO,198,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.719,-3.652,1.933,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.168804,0.00835002,0.165342 kka2_1:2_G201H,kka2_1:2_201,Kka2,kka2_1:2,P00552,0.165364,NO,201,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.56,-3.46,1.9,,0.149,T,l,0.29,-0.57,16.092,16.092,52.65,POB,-1.92233,0.295029,0.00820117,0.165364 kka2_1:2_L232N,kka2_1:2_232,Kka2,kka2_1:2,P00552,0.165395,NO,232,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.514,-4.176,2.662,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.295029,0.00800103,0.165395 beta-lactamase_2500_I125D,beta-lactamase_2500_125,TEM-1,beta-lactamase_2500,P62593,0.165418,NO,125,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.441,-3.998,2.557,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.361275,0.00383964,0.165418 beta-lactamase_156_V42R,beta-lactamase_156_42,TEM-1,beta-lactamase_156,P62593,0.165443,NO,42,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.564,-4.138,2.574,,0.017,E,B,0.44,-0.51,2.576,,63.99,BHO,-1.042,0.111618,0.00404515,0.165443 kka2_1:8_L212W,kka2_1:8_212,Kka2,kka2_1:8,P00552,0.165473,NO,212,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.904,-5.226,4.322,,,,B,1.59,-0.78,1.708,,42.42,BHO,-0.799667,0.100394,0.0031426,0.165473 kka2_1:8_L212W,kka2_1:8_212,Kka2,kka2_1:8,P00552,0.165473,NO,212,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.904,-5.226,4.322,,,,B,1.59,-0.78,1.708,,42.42,BHO,-0.799667,0.100394,0.0031426,0.165473 beta-lactamase_2500_M209S,beta-lactamase_2500_209,TEM-1,beta-lactamase_2500,P62593,0.165474,NO,209,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.442,-3.579,2.137,,,H,A,0.55,-0.97,3.229,,64.69,HHA,-1.52633,0.361275,0.00625021,0.165474 beta-lactamase_V258D,beta-lactamase_258,TEM-1,beta-lactamase,P62593,0.165495,NO,258,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.975,-3.818,1.843,5.16083,,E,B,1.64,-1.02,2.124,,67.83,HHH,-1.67667,0.221079,0.007931,0.165495 beta-lactamase_A77P,beta-lactamase_77,TEM-1,beta-lactamase,P62593,0.165513,NO,77,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.234,-3.879,2.645,4.75777,0.039,H,A,0.52,-0.56,1.708,,64.34,OHH,-1.294,0.221079,0.00282362,0.165513 kka2_1:2_V185P,kka2_1:2_185,Kka2,kka2_1:2,P00552,0.165528,NO,185,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.045,-4.002,2.957,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.295029,0.00367031,0.165528 kka2_1:1_I196H,kka2_1:1_196,Kka2,kka2_1:1,P00552,0.165553,NO,196,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-2.115,-4.791,2.676,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.520039,0.0107273,0.165553 beta-lactamase_2500_K232H,beta-lactamase_2500_232,TEM-1,beta-lactamase_2500,P62593,0.165597,NO,232,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.012,-4.433,3.421,,,E,B,2.34,-1.1,3.048,,65.03,ABP,-1.238,0.361275,0.00313441,0.165597 beta-lactamase_2500_S233V,beta-lactamase_2500_233,TEM-1,beta-lactamase_2500,P62593,0.165673,NO,233,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.886,-3.357,1.471,,0.016,E,B,0.27,-1.01,2.851,,77.62,BPO,-1.17267,0.361275,0.00311415,0.165673 beta-lactamase_2500_L191G,beta-lactamase_2500_191,TEM-1,beta-lactamase_2500,P62593,0.165676,NO,191,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.087,-3.655,2.568,,,H,A,0.55,0.09,1.703,,63.29,BHH,-1.445,0.361275,0.00263549,0.165676 beta-lactamase_M1Y,beta-lactamase_1,TEM-1,beta-lactamase,P62593,0.165716,NO,1,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.998,-3.619,1.621,,,,,,,,,,OHP,-1.97,0.221079,0.00162771,0.165716 beta-lactamase_156_Y262P,beta-lactamase_156_262,TEM-1,beta-lactamase_156,P62593,0.165776,NO,262,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.111618,0.00853516,0.165776 beta-lactamase_39_S128F,beta-lactamase_39_128,TEM-1,beta-lactamase_39,P62593,0.16578,NO,128,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-0.84,-4.067,3.227,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.0495842,0.00071483,0.16578 kka2_1:1_V185P,kka2_1:1_185,Kka2,kka2_1:1,P00552,0.165786,NO,185,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.045,-4.002,2.957,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.520039,0.00367031,0.165786 beta-lactamase_156_G281D,beta-lactamase_156_281,TEM-1,beta-lactamase_156,P62593,0.165828,NO,281,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.111618,0.0406482,0.165828 kka2_1:2_G30L,kka2_1:2_30,Kka2,kka2_1:2,P00552,0.165839,NO,30,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.596,-3.836,3.24,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.295029,0.00159208,0.165839 beta-lactamase_625_R81P,beta-lactamase_625_81,TEM-1,beta-lactamase_625,P62593,0.165871,NO,81,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.466,-3.949,2.483,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.213352,0.00499763,0.165871 beta-lactamase_156_A124Y,beta-lactamase_156_124,TEM-1,beta-lactamase_156,P62593,0.165906,NO,124,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.181,-4.228,3.047,,,H,A,0.46,-0.9,2.027,,64.34,HHH,-1.152,0.111618,0.00481399,0.165906 beta-lactamase_156_A246E,beta-lactamase_156_246,TEM-1,beta-lactamase_156,P62593,0.165922,NO,246,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.121,-3.906,1.785,,0.01,E,B,0.46,-1.01,1.959,,73.78,HHH,-1.55633,0.111618,0.00569458,0.165922 kka2_1:1_V185N,kka2_1:1_185,Kka2,kka2_1:1,P00552,0.16595,NO,185,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.045,-4.197,3.152,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.520039,0.00367031,0.16595 kka2_1:4_V49E,kka2_1:4_49,Kka2,kka2_1:4,P00552,0.165951,NO,49,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.614,-3.892,2.278,,,E,B,0.44,-0.77,1.233,,64.39,HHB,-1.3,0.168804,0.00615685,0.165951 beta-lactamase_2500_D129Y,beta-lactamase_2500_129,TEM-1,beta-lactamase_2500,P62593,0.16596,NO,129,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.816,-4.385,3.569,,,,B,0.75,-0.69,1.29,,34.97,PAP,-0.818,0.361275,0.00109178,0.16596 kka2_1:4_H135K,kka2_1:4_135,Kka2,kka2_1:4,P00552,0.165991,NO,135,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-1.331,-3.419,2.088,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.168804,0.00532566,0.165991 beta-lactamase_2500_L79R,beta-lactamase_2500_79,TEM-1,beta-lactamase_2500,P62593,0.166022,NO,79,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.842,-3.93,3.088,,0.007,H,A,0.55,-0.16,0.823,,50.35,HHP,-1.44333,0.361275,0.000947397,0.166022 beta-lactamase_156_E164R,beta-lactamase_156_164,TEM-1,beta-lactamase_156,P62593,0.166067,NO,164,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-0.948,-3.511,2.563,,0.011,T,B,1.04,-0.4,3.445,,64.69,HAO,-1.388,0.111618,0.00137286,0.166067 kka2_1:8_L94H,kka2_1:8_94,Kka2,kka2_1:8,P00552,0.166098,NO,94,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.618,-4.931,3.313,,0.058,E,B,1.59,-0.52,2.197,,56.06,HHO,-1.612,0.100394,0.00520888,0.166098 kka2_1:8_L94H,kka2_1:8_94,Kka2,kka2_1:8,P00552,0.166098,NO,94,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.618,-4.931,3.313,,0.058,E,B,1.59,-0.52,2.197,,56.06,HHO,-1.612,0.100394,0.00520888,0.166098 kka2_1:2_I254P,kka2_1:2_254,Kka2,kka2_1:2,P00552,0.16616,NO,254,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.933,-4.189,2.256,,0.135,H,A,1.52,-0.6,2.562,,71.59,BHH,-1.668,0.295029,0.0132375,0.16616 beta-lactamase_156_G76R,beta-lactamase_156_76,TEM-1,beta-lactamase_156,P62593,0.166175,NO,76,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.189,-3.905,2.716,,,H,A,0.29,-0.67,3.059,,67.83,OOH,-1.22267,0.111618,0.00476637,0.166175 beta-lactamase_625_L192D,beta-lactamase_625_192,TEM-1,beta-lactamase_625,P62593,0.166219,NO,192,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.254,-4.104,2.85,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.213352,0.00558728,0.166219 beta-lactamase_39_P181F,beta-lactamase_39_181,TEM-1,beta-lactamase_39,P62593,0.166283,NO,181,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.813,-4.48,3.667,,,H,A,0.52,-1.14,1.946,,61.54,HOH,-1.795,0.0495842,0.000703122,0.166283 kka2_1:8_L193Y,kka2_1:8_193,Kka2,kka2_1:8,P00552,0.166307,NO,193,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.983,-4.078,3.095,,,G,A,1.59,-1.03,2.234,,65.53,OHO,-0.965333,0.100394,0.00480179,0.166307 kka2_1:8_L193Y,kka2_1:8_193,Kka2,kka2_1:8,P00552,0.166307,NO,193,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.983,-4.078,3.095,,,G,A,1.59,-1.03,2.234,,65.53,OHO,-0.965333,0.100394,0.00480179,0.166307 kka2_1:4_I221Y,kka2_1:4_221,Kka2,kka2_1:4,P00552,0.166367,NO,221,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.739,-4.012,2.273,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.168804,0.00945908,0.166367 beta-lactamase_2500_L248G,beta-lactamase_2500_248,TEM-1,beta-lactamase_2500,P62593,0.166377,NO,248,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.794,-3.512,1.718,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.361275,0.00428493,0.166377 kka2_1:2_S32M,kka2_1:2_32,Kka2,kka2_1:2,P00552,0.166377,NO,32,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-0.804,-4.508,3.704,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.295029,0.00149998,0.166377 kka2_1:1_A34Y,kka2_1:1_34,Kka2,kka2_1:1,P00552,0.166382,NO,34,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.928,-4.223,3.295,,0.417,.,B,0.46,2.29,0.262,,52.27,AHH,-1.747,0.520039,0.00343484,0.166382 beta-lactamase_625_I244P,beta-lactamase_625_244,TEM-1,beta-lactamase_625,P62593,0.166479,NO,244,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.555,-4.01,2.455,,,E,B,0.48,-0.84,2.061,,77.62,OHH,-1.385,0.213352,0.00605379,0.166479 kka2_1:8_G210W,kka2_1:8_210,Kka2,kka2_1:8,P00552,0.166515,NO,210,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.095,-5.322,4.227,,0.103,T,A,0.75,-0.62,2.687,,50,OOB,-0.966667,0.100394,0.00598378,0.166515 kka2_1:8_G210W,kka2_1:8_210,Kka2,kka2_1:8,P00552,0.166515,NO,210,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.095,-5.322,4.227,,0.103,T,A,0.75,-0.62,2.687,,50,OOB,-0.966667,0.100394,0.00598378,0.166515 beta-lactamase_625_K71T,beta-lactamase_625_71,TEM-1,beta-lactamase_625,P62593,0.166573,NO,71,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-0.8,-3.421,2.621,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.213352,0.00103192,0.166573 beta-lactamase_625_D155M,beta-lactamase_625_155,TEM-1,beta-lactamase_625,P62593,0.166583,NO,155,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.889,-4.929,4.04,,0.049,,B,0.75,-0.9,4.922,,64.69,OAB,-1.62267,0.213352,0.00135315,0.166583 kka2_1:2_A222H,kka2_1:2_222,Kka2,kka2_1:2,P00552,0.166587,NO,222,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.725,-4.708,3.983,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.295029,0.00207657,0.166587 beta-lactamase_2500_A133W,beta-lactamase_2500_133,TEM-1,beta-lactamase_2500,P62593,0.166609,NO,133,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.186,-5.303,4.117,,,H,A,0.46,-0.86,2.649,,67.83,HHP,-0.988333,0.361275,0.00468022,0.166609 kka2_1:4_V49D,kka2_1:4_49,Kka2,kka2_1:4,P00552,0.166641,NO,49,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.614,-4.094,2.48,,,E,B,0.44,-0.77,1.233,,64.39,HHB,-1.3,0.168804,0.00615685,0.166641 beta-lactamase_625_T107D,beta-lactamase_625_107,TEM-1,beta-lactamase_625,P62593,0.166648,NO,107,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.117,-3.478,2.361,,,G,A,0.22,-0.06,3.676,,67.83,HPA,-1.265,0.213352,0.00239347,0.166648 beta-lactamase_625_D155H,beta-lactamase_625_155,TEM-1,beta-lactamase_625,P62593,0.166658,NO,155,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.889,-4.424,3.535,,0.049,,B,0.75,-0.9,4.922,,64.69,OAB,-1.62267,0.213352,0.00135315,0.166658 beta-lactamase_39_E164G,beta-lactamase_39_164,TEM-1,beta-lactamase_39,P62593,0.166681,NO,164,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-0.948,-2.443,1.495,,0.011,T,B,1.04,-0.4,0.664,,64.69,HAO,-1.388,0.0495842,0.00137286,0.166681 beta-lactamase_156_I244G,beta-lactamase_156_244,TEM-1,beta-lactamase_156,P62593,0.166693,NO,244,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.555,-3.714,2.159,,,E,B,0.48,-0.84,1.325,,77.62,OHH,-1.385,0.111618,0.00605379,0.166693 beta-lactamase_2500_S233D,beta-lactamase_2500_233,TEM-1,beta-lactamase_2500,P62593,0.166764,NO,233,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.886,-3.5,1.614,,0.016,E,B,0.27,-1.01,2.851,,77.62,BPO,-1.17267,0.361275,0.00311415,0.166764 beta-lactamase_39_L135P,beta-lactamase_39_135,TEM-1,beta-lactamase_39,P62593,0.166892,NO,135,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.002,-4.134,3.132,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.0495842,0.00244423,0.166892 kka2_1:1_L94G,kka2_1:1_94,Kka2,kka2_1:1,P00552,0.166914,NO,94,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.618,-3.801,2.183,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.520039,0.00520888,0.166914 beta-lactamase_625_I229K,beta-lactamase_625_229,TEM-1,beta-lactamase_625,P62593,0.166918,NO,229,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.267,-3.862,2.595,,0.083,E,B,0.48,-0.76,1.69,,50,HHH,-1.58767,0.213352,0.00477249,0.166918 kka2_1:8_F206D,kka2_1:8_206,Kka2,kka2_1:8,P00552,0.166931,NO,206,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.349,-4.082,2.733,,0.006,E,B,1.62,-1.21,1.052,,63.64,OHH,-1.04,0.100394,0.00936868,0.166931 kka2_1:8_F206D,kka2_1:8_206,Kka2,kka2_1:8,P00552,0.166931,NO,206,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.349,-4.082,2.733,,0.006,E,B,1.62,-1.21,1.052,,63.64,OHH,-1.04,0.100394,0.00936868,0.166931 beta-lactamase_T179M,beta-lactamase_179,TEM-1,beta-lactamase,P62593,0.166936,NO,179,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.085,-4.564,3.479,5.07116,,E,B,0.8,-1.38,1.859,,73.08,PPH,-1.557,0.221079,0.00226045,0.166936 beta-lactamase_156_E56P,beta-lactamase_156_56,TEM-1,beta-lactamase_156,P62593,0.166942,NO,56,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.043,-3.731,1.688,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.111618,0.00238534,0.166942 PSD95pdz3_H372E,PSD95pdz3_372,PSD95pdz3,PSD95pdz3,P31016,0.166946,NO,372,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-1.627,-2.897,1.27,5.5607,,,,,17.008,,,,PBA,-1.63033,0.0758425,0.00040301,0.166946 beta-lactamase_2500_L47G,beta-lactamase_2500_47,TEM-1,beta-lactamase_2500,P62593,0.166978,NO,47,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.876,-3.777,1.901,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.361275,0.00439844,0.166978 beta-lactamase_625_K232N,beta-lactamase_625_232,TEM-1,beta-lactamase_625,P62593,0.166981,NO,232,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.012,-3.49,2.478,,,E,B,2.34,-1.1,1.992,,65.03,ABP,-1.238,0.213352,0.00313441,0.166981 beta-lactamase_156_V31Q,beta-lactamase_156_31,TEM-1,beta-lactamase_156,P62593,0.166986,NO,31,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.822,-4.296,2.474,,,H,A,0.44,-0.46,4.126,,73.78,BHB,-2.03767,0.111618,0.00478065,0.166986 beta-lactamase_2500_G43E,beta-lactamase_2500_43,TEM-1,beta-lactamase_2500,P62593,0.167076,NO,43,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.62,-3.665,3.045,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.361275,0.00120151,0.167076 beta-lactamase_625_E35W,beta-lactamase_625_35,TEM-1,beta-lactamase_625,P62593,0.167084,NO,35,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-0.869,-5.371,4.502,,0.15,H,A,1.04,0.21,0.664,,46.85,HAA,-1.88667,0.213352,0.00174441,0.167084 beta-lactamase_156_G243R,beta-lactamase_156_243,TEM-1,beta-lactamase_156,P62593,0.167164,NO,243,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.532,,,,,E,B,0.77,-1.24,2.866,,50,BOH,-1.46867,0.111618,0.00464034,0.167164 beta-lactamase_2500_W288V,beta-lactamase_2500_288,TEM-1,beta-lactamase_2500,P62593,0.167232,NO,288,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,,,,,,,,,,,,,BHO,,0.361275,,0.167232 beta-lactamase_V106P,beta-lactamase_106,TEM-1,beta-lactamase,P62593,0.167268,NO,106,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.218,-4.094,2.876,5.23115,0.258,T,A,0.96,0.24,1.188,,72.73,OHP,-1.04933,0.221079,0.00304168,0.167268 kka2_1:1_Q219A,kka2_1:1_219,Kka2,kka2_1:1,P00552,0.167353,NO,219,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-0.93,-3.129,2.199,,0.088,H,A,0.4,-0.85,1.917,,50,HPA,-1.05167,0.520039,0.00237913,0.167353 kka2_1:4_V186K,kka2_1:4_186,Kka2,kka2_1:4,P00552,0.167358,NO,186,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.011,-3.841,2.83,,,E,B,0.44,-0.61,0.679,,45.83,HHP,-1.10967,0.168804,0.00409703,0.167358 kka2_1:4_I221K,kka2_1:4_221,Kka2,kka2_1:4,P00552,0.16748,NO,221,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.739,-3.896,2.157,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.168804,0.00945908,0.16748 beta-lactamase_625_K232L,beta-lactamase_625_232,TEM-1,beta-lactamase_625,P62593,0.167504,NO,232,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.012,-3.401,2.389,,,E,B,2.34,-1.1,1.992,,65.03,ABP,-1.238,0.213352,0.00313441,0.167504 beta-lactamase_625_P181R,beta-lactamase_625_181,TEM-1,beta-lactamase_625,P62593,0.16753,NO,181,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.813,-3.93,3.117,,,H,A,0.52,-1.14,1.797,,61.54,HOH,-1.795,0.213352,0.000703122,0.16753 beta-lactamase_39_E164H,beta-lactamase_39_164,TEM-1,beta-lactamase_39,P62593,0.167535,NO,164,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-0.948,-4.339,3.391,,0.011,T,B,1.04,-0.4,0.664,,64.69,HAO,-1.388,0.0495842,0.00137286,0.167535 kka2_1:1_M197E,kka2_1:1_197,Kka2,kka2_1:1,P00552,0.167572,NO,197,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.707,-3.927,2.22,,0.121,E,B,1.59,-1.19,2.097,,65.53,HHH,-1.847,0.520039,0.00921295,0.167572 beta-lactamase_T158Q,beta-lactamase_158,TEM-1,beta-lactamase,P62593,0.167583,NO,158,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.116,-3.908,2.792,5.32011,0.036,,B,0.98,-0.85,2.755,,69.58,HPB,-1.269,0.221079,0.00341825,0.167583 kka2_1:2_A144L,kka2_1:2_144,Kka2,kka2_1:2,P00552,0.167592,NO,144,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.859,-3.107,2.248,,,H,A,0.46,0.21,6.844,,52.65,BHB,-1.72933,0.295029,0.00231095,0.167592 kka2_1:2_L184A,kka2_1:2_184,Kka2,kka2_1:2,P00552,0.1677,NO,184,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.496,-2.814,1.318,,0.489,E,B,0.55,-0.06,14.044,14.044,63.26,AHH,-1.24833,0.295029,0.00518742,0.1677 beta-lactamase_625_E164P,beta-lactamase_625_164,TEM-1,beta-lactamase_625,P62593,0.167703,NO,164,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-0.948,-3.725,2.777,,0.011,T,B,1.04,-0.4,1.321,,64.69,HAO,-1.388,0.213352,0.00137286,0.167703 kka2_1:1_L259G,kka2_1:1_259,Kka2,kka2_1:1,P00552,0.167751,NO,259,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.088,-3.711,2.623,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.520039,0.0206964,0.167751 kka2_1:8_T187F,kka2_1:8_187,Kka2,kka2_1:8,P00552,0.167761,NO,187,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.273,-4.193,2.92,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.100394,0.00693073,0.167761 kka2_1:8_T187F,kka2_1:8_187,Kka2,kka2_1:8,P00552,0.167761,NO,187,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.273,-4.193,2.92,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.100394,0.00693073,0.167761 kka2_1:1_A224M,kka2_1:1_224,Kka2,kka2_1:1,P00552,0.16779,NO,224,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.977,-4.55,3.573,,,H,A,0.46,-1.26,1.725,,63.64,HHP,-1.41033,0.520039,0.00352047,0.16779 kka2_1:2_L223Q,kka2_1:2_223,Kka2,kka2_1:2,P00552,0.167816,NO,223,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.861,-4.235,3.374,,,H,A,0.55,-1.24,0.266,,50,HHH,-0.854333,0.295029,0.00253574,0.167816 beta-lactamase_156_D129R,beta-lactamase_156_129,TEM-1,beta-lactamase_156,P62593,0.167858,NO,129,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.816,-3.896,3.08,,,,B,0.75,-0.69,1.924,,34.97,PAP,-0.818,0.111618,0.00109178,0.167858 beta-lactamase_2500_G249H,beta-lactamase_2500_249,TEM-1,beta-lactamase_2500,P62593,0.167881,NO,249,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.312,,,,0.256,S,B,0.23,0.04,30.841,30.841,72.73,HOO,-1.81367,0.361275,0.00220169,0.167881 beta-lactamase_156_V31H,beta-lactamase_156_31,TEM-1,beta-lactamase_156,P62593,0.167901,NO,31,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.822,-4.968,3.146,,,H,A,0.44,-0.46,4.126,,73.78,BHB,-2.03767,0.111618,0.00478065,0.167901 kka2_1:2_L170Q,kka2_1:2_170,Kka2,kka2_1:2,P00552,0.167961,NO,170,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.28,-4.219,2.939,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.295029,0.00730791,0.167961 E1_Ubiquitin_G76V,E1_Ubiquitin_76,Uba1,E1_Ubiquitin,P0CG63,0.167993,NO,76,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.999,-3.624,2.625,,0.23,,B,0.75,0.08,1.702,,83.73,OOO,-0.999,0.18783,0.00125575,0.167993 beta-lactamase_2500_G243Q,beta-lactamase_2500_243,TEM-1,beta-lactamase_2500,P62593,0.168038,NO,243,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.361275,0.00464034,0.168038 beta-lactamase_625_I125D,beta-lactamase_625_125,TEM-1,beta-lactamase_625,P62593,0.168062,NO,125,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.441,-3.998,2.557,,,H,A,0.48,-0.7,2.034,,63.29,HHP,-1.248,0.213352,0.00383964,0.168062 beta-lactamase_2500_E119F,beta-lactamase_2500_119,TEM-1,beta-lactamase_2500,P62593,0.168151,NO,119,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.412,-4.398,2.986,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.361275,0.00386966,0.168151 beta-lactamase_T187K,beta-lactamase_187,TEM-1,beta-lactamase,P62593,0.168157,NO,187,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.401,-3.578,2.177,5.11453,0.007,H,A,0.3,-1.19,1.751,,67.48,PPH,-1.69633,0.221079,0.00491782,0.168157 beta-lactamase_2500_A133I,beta-lactamase_2500_133,TEM-1,beta-lactamase_2500,P62593,0.168221,NO,133,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.186,-3.823,2.637,,,H,A,0.46,-0.86,2.649,,67.83,HHP,-0.988333,0.361275,0.00468022,0.168221 beta-lactamase_39_A133R,beta-lactamase_39_133,TEM-1,beta-lactamase_39,P62593,0.168242,NO,133,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.186,-3.865,2.679,,,H,A,0.46,-0.86,0.373,,67.83,HHP,-0.988333,0.0495842,0.00468022,0.168242 WW_domain_Y188D,WW_domain_188,Yap65,WW_domain,P46937,0.168265,NO,188,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-1.326,-3.759,2.433,5.89734,,,,,,,,,BHH,-1.45333,0.153962,0.00265487,0.168265 kka2_1:1_F48M,kka2_1:1_48,Kka2,kka2_1:1,P00552,0.168297,NO,48,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.453,-4.369,2.916,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.520039,0.00475422,0.168297 beta-lactamase_625_D129M,beta-lactamase_625_129,TEM-1,beta-lactamase_625,P62593,0.168362,NO,129,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.816,-4.927,4.111,,,,B,0.75,-0.69,0.171,,34.97,PAP,-0.818,0.213352,0.00109178,0.168362 kka2_1:1_G245E,kka2_1:1_245,Kka2,kka2_1:1,P00552,0.168363,NO,245,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.812,-2.733,1.921,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.520039,0.00683899,0.168363 kka2_1:4_L126W,kka2_1:4_126,Kka2,kka2_1:4,P00552,0.168385,NO,126,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.246,-5.346,4.1,,0.285,S,B,0.55,0.12,0.302,,51.89,PHA,-1.744,0.168804,0.0066485,0.168385 beta-lactamase_39_I125R,beta-lactamase_39_125,TEM-1,beta-lactamase_39,P62593,0.168391,NO,125,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.441,-4.126,2.685,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.0495842,0.00383964,0.168391 beta-lactamase_L150D,beta-lactamase_150,TEM-1,beta-lactamase,P62593,0.168396,NO,150,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.326,-4.043,2.717,5.15566,,H,A,1.75,-0.2,1.615,,62.94,HHB,-1.86167,0.221079,0.00463171,0.168396 beta-lactamase_156_E164P,beta-lactamase_156_164,TEM-1,beta-lactamase_156,P62593,0.168402,NO,164,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-0.948,-3.725,2.777,,0.011,T,B,1.04,-0.4,3.445,,64.69,HAO,-1.388,0.111618,0.00137286,0.168402 beta-lactamase_625_I45K,beta-lactamase_625_45,TEM-1,beta-lactamase_625,P62593,0.168427,NO,45,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-2.421,-3.76,1.339,,,E,B,0.48,-0.3,3.642,,77.62,HHA,-2.30267,0.213352,0.00452842,0.168427 kka2_1:1_E169M,kka2_1:1_169,Kka2,kka2_1:1,P00552,0.168444,NO,169,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.996,-3.601,1.605,,0.422,H,A,1.04,0.3,7.546,7.546,65.53,HAH,-1.755,0.520039,0.00730086,0.168444 beta-lactamase_2500_P65Y,beta-lactamase_2500_65,TEM-1,beta-lactamase_2500,P62593,0.168453,NO,65,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.894,-4.31,3.416,,0.098,E,B,0.52,-0.62,0.3,,40.56,HOH,-1.03233,0.361275,0.00152776,0.168453 beta-lactamase_S233R,beta-lactamase_233,TEM-1,beta-lactamase,P62593,0.168472,NO,233,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.886,-3.819,1.933,4.98121,0.016,E,B,0.48,-1.01,5.361,,77.62,BPO,-1.17267,0.221079,0.00311415,0.168472 kka2_1:2_Y244E,kka2_1:2_244,Kka2,kka2_1:2,P00552,0.168491,NO,244,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-0.775,-3.693,2.918,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.295029,0.00453187,0.168491 beta-lactamase_2500_F64I,beta-lactamase_2500_64,TEM-1,beta-lactamase_2500,P62593,0.168498,NO,64,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-0.841,-3.335,2.494,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.361275,0.000947691,0.168498 beta-lactamase_2500_L218E,beta-lactamase_2500_218,TEM-1,beta-lactamase_2500,P62593,0.168622,NO,218,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.391,-3.611,2.22,,,I,b,0.55,-0.53,9.151,9.151,74.48,OHH,-1.58867,0.361275,0.00618274,0.168622 beta-lactamase_625_L192R,beta-lactamase_625_192,TEM-1,beta-lactamase_625,P62593,0.168626,NO,192,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.254,-4.095,2.841,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.213352,0.00558728,0.168626 kka2_1:1_A56N,kka2_1:1_56,Kka2,kka2_1:1,P00552,0.168672,NO,56,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.083,-3.917,1.834,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.520039,0.00717715,0.168672 beta-lactamase_156_C75F,beta-lactamase_156_75,TEM-1,beta-lactamase_156,P62593,0.168678,NO,75,C,F,CF,Special,Hydrophobic,5.07,3.32051,-1.74949,205,121,165,44,108.5,189.9,81.4,-1.245,-4.17,2.925,,,H,A,0.46,-0.87,0.876,,50,HOO,-1.24333,0.111618,0.0034616,0.168678 beta-lactamase_2500_T107Q,beta-lactamase_2500_107,TEM-1,beta-lactamase_2500,P62593,0.168725,NO,107,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.117,-3.889,2.772,,,G,A,0.22,-0.06,2.686,,67.83,HPA,-1.265,0.361275,0.00239347,0.168725 beta-lactamase_625_K71G,beta-lactamase_625_71,TEM-1,beta-lactamase_625,P62593,0.168735,NO,71,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-0.8,-3.358,2.558,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.213352,0.00103192,0.168735 kka2_1:4_S32E,kka2_1:4_32,Kka2,kka2_1:4,P00552,0.16874,NO,32,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-0.804,-3.243,2.439,,0.768,S,b,0.27,3.75,,,,OPA,-1.74533,0.168804,0.00149998,0.16874 kka2_1:2_L193Y,kka2_1:2_193,Kka2,kka2_1:2,P00552,0.168746,NO,193,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.983,-4.078,3.095,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.295029,0.00480179,0.168746 kka2_1:1_I228Y,kka2_1:1_228,Kka2,kka2_1:1,P00552,0.16893,NO,228,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.142,-4.038,2.896,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.520039,0.00458834,0.16893 beta-lactamase_2500_S128D,beta-lactamase_2500_128,TEM-1,beta-lactamase_2500,P62593,0.169071,NO,128,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-0.84,-3.244,2.404,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.361275,0.00071483,0.169071 kka2_1:2_F203H,kka2_1:2_203,Kka2,kka2_1:2,P00552,0.169116,NO,203,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-0.911,-4.571,3.66,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.295029,0.00318738,0.169116 beta-lactamase_156_F64G,beta-lactamase_156_64,TEM-1,beta-lactamase_156,P62593,0.169136,NO,64,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-0.841,-3.583,2.742,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.111618,0.000947691,0.169136 beta-lactamase_2500_A246Q,beta-lactamase_2500_246,TEM-1,beta-lactamase_2500,P62593,0.169191,NO,246,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.121,-4.263,2.142,,0.01,E,B,0.46,-1.01,0.753,,73.78,HHH,-1.55633,0.361275,0.00569458,0.169191 beta-lactamase_625_M209V,beta-lactamase_625_209,TEM-1,beta-lactamase_625,P62593,0.169208,NO,209,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.442,-2.446,1.004,,,H,A,0.55,-0.97,1.167,,64.69,HHA,-1.52633,0.213352,0.00625021,0.169208 kka2_1:8_G233E,kka2_1:8_233,Kka2,kka2_1:8,P00552,0.169208,NO,233,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.748,-3.501,2.753,,0.172,,b,0.75,-0.27,1.134,,49.24,HOO,-1.72067,0.100394,0.00232366,0.169208 kka2_1:8_G233E,kka2_1:8_233,Kka2,kka2_1:8,P00552,0.169208,NO,233,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.748,-3.501,2.753,,0.172,,b,0.75,-0.27,1.134,,49.24,HOO,-1.72067,0.100394,0.00232366,0.169208 kka2_1:1_T187L,kka2_1:1_187,Kka2,kka2_1:1,P00552,0.169256,NO,187,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.273,-3.26,1.987,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.520039,0.00693073,0.169256 Pab1_N127L,Pab1_127,Pab1,Pab1,P04147,0.169276,NO,127,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-1.079,-3.4,2.321,,0.138,E,B,1.05,-0.51,,,,OPH,-1.13633,0.175299,0.000805159,0.169276 beta-lactamase_156_M209K,beta-lactamase_156_209,TEM-1,beta-lactamase_156,P62593,0.169293,NO,209,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.442,-3.673,2.231,,,H,A,0.55,-0.97,1.066,,64.69,HHA,-1.52633,0.111618,0.00625021,0.169293 kka2_1:2_F203Y,kka2_1:2_203,Kka2,kka2_1:2,P00552,0.169349,NO,203,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-0.911,-3.189,2.278,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.295029,0.00318738,0.169349 Ubiquitin_L71K,Ubiquitin_71,Uba1,Ubiquitin,P0CG48,0.169355,NO,71,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.647,-3.74,2.093,5.02588,0.591,E,B,2.89,-0.69,4.365,,34.31,HHB,-1.85167,0.205827,0.000949314,0.169355 Ubiquitin_R72Y,Ubiquitin_72,Uba1,Ubiquitin,P0CG48,0.169355,NO,72,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.034,-3.168,1.134,5.19484,0.077,,B,1.41,-0.1,9.638,9.638,42.77,HBH,-1.82733,0.205827,0.000768249,0.169355 Ubiquitin_V70K,Ubiquitin_70,Uba1,Ubiquitin,P0CG48,0.169355,NO,70,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.874,-3.725,1.851,5.29728,0.05,E,B,0.96,-0.97,2.363,,34.31,HHH,-1.65533,0.205827,0.00106871,0.169355 beta-lactamase_156_M184R,beta-lactamase_156_184,TEM-1,beta-lactamase_156,P62593,0.169361,NO,184,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.593,-3.928,2.335,,,H,A,0.55,-0.87,1.671,,62.94,HHH,-1.41,0.111618,0.00356019,0.169361 beta-lactamase_2500_A132I,beta-lactamase_2500_132,TEM-1,beta-lactamase_2500,P62593,0.16941,NO,132,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.9,-3.489,2.589,,,H,A,0.46,-0.93,8.408,,64.69,PHH,-1.138,0.361275,0.000962524,0.16941 beta-lactamase_2500_W288T,beta-lactamase_2500_288,TEM-1,beta-lactamase_2500,P62593,0.169426,NO,288,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,,,,,,,,,,,,,BHO,,0.361275,,0.169426 beta-lactamase_N272P,beta-lactamase_272,TEM-1,beta-lactamase,P62593,0.169431,NO,272,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-1.127,-3.888,2.761,5.37826,0.081,H,A,0.09,-0.97,1.468,,63.64,BPB,-1.56333,0.221079,0.00545371,0.169431 beta-lactamase_625_K232I,beta-lactamase_625_232,TEM-1,beta-lactamase_625,P62593,0.169472,NO,232,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.012,-4.053,3.041,,,E,B,2.34,-1.1,1.992,,65.03,ABP,-1.238,0.213352,0.00313441,0.169472 beta-lactamase_156_T158D,beta-lactamase_156_158,TEM-1,beta-lactamase_156,P62593,0.1695,NO,158,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.116,-3.478,2.362,,0.036,,B,0.22,-0.85,3.771,,69.58,HPB,-1.269,0.111618,0.00341825,0.1695 kka2_1:1_R226N,kka2_1:1_226,Kka2,kka2_1:1,P00552,0.1695,NO,226,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.392,-3.682,2.29,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.520039,0.0108032,0.1695 kka2_1:2_L123Q,kka2_1:2_123,Kka2,kka2_1:2,P00552,0.16955,NO,123,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.888,-4.152,3.264,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.295029,0.00325188,0.16955 kka2_1:2_L102Y,kka2_1:2_102,Kka2,kka2_1:2,P00552,0.169589,NO,102,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.804,-3.989,3.185,,,T,A,1.59,-1.17,4.258,,42.42,AHH,-1.398,0.295029,0.00201332,0.169589 beta-lactamase_625_A132M,beta-lactamase_625_132,TEM-1,beta-lactamase_625,P62593,0.1696,NO,132,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.9,-4.473,3.573,,,H,A,0.46,-0.93,0.316,,64.69,PHH,-1.138,0.213352,0.000962524,0.1696 kka2_1:2_T73Y,kka2_1:2_73,Kka2,kka2_1:2,P00552,0.169607,NO,73,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.51,-3.328,0.818,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.295029,0.00628605,0.169607 kka2_1:8_D220K,kka2_1:8_220,Kka2,kka2_1:8,P00552,0.169621,NO,220,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.787,-3.529,2.742,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.100394,0.00158066,0.169621 kka2_1:8_D220K,kka2_1:8_220,Kka2,kka2_1:8,P00552,0.169621,NO,220,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.787,-3.529,2.742,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.100394,0.00158066,0.169621 kka2_1:4_V97K,kka2_1:4_97,Kka2,kka2_1:4,P00552,0.16965,NO,97,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.453,-3.837,2.384,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.168804,0.00737869,0.16965 beta-lactamase_D177F,beta-lactamase_177,TEM-1,beta-lactamase,P62593,0.169665,NO,177,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.967,-4.34,3.373,5.08038,0.006,T,L,1.59,-1.02,3.536,,64.69,BAP,-0.873667,0.221079,0.000864022,0.169665 beta-lactamase_I256W,beta-lactamase_256,TEM-1,beta-lactamase,P62593,0.169665,NO,256,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.621,-5.303,3.682,5.3196,,E,B,1,-0.84,1.615,,73.08,BHH,-1.80667,0.221079,0.00710634,0.169665 beta-lactamase_156_E164N,beta-lactamase_156_164,TEM-1,beta-lactamase_156,P62593,0.16967,NO,164,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-0.948,-3.497,2.549,,0.011,T,B,1.04,-0.4,3.445,,64.69,HAO,-1.388,0.111618,0.00137286,0.16967 beta-lactamase_156_S233F,beta-lactamase_156_233,TEM-1,beta-lactamase_156,P62593,0.169674,NO,233,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.886,-4.226,2.34,,0.016,E,B,0.27,-1.01,4.111,,77.62,BPO,-1.17267,0.111618,0.00311415,0.169674 kka2_1:8_F48M,kka2_1:8_48,Kka2,kka2_1:8,P00552,0.169827,NO,48,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.453,-4.369,2.916,,0.296,E,B,1.62,-0.99,14.194,14.194,55.3,HHH,-1.444,0.100394,0.00475422,0.169827 kka2_1:8_F48M,kka2_1:8_48,Kka2,kka2_1:8,P00552,0.169827,NO,48,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.453,-4.369,2.916,,0.296,E,B,1.62,-0.99,14.194,14.194,55.3,HHH,-1.444,0.100394,0.00475422,0.169827 kka2_1:8_T187Q,kka2_1:8_187,Kka2,kka2_1:8,P00552,0.169827,NO,187,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.273,-4.098,2.825,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.100394,0.00693073,0.169827 kka2_1:8_T187Q,kka2_1:8_187,Kka2,kka2_1:8,P00552,0.169827,NO,187,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.273,-4.098,2.825,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.100394,0.00693073,0.169827 kka2_1:4_M197E,kka2_1:4_197,Kka2,kka2_1:4,P00552,0.169847,NO,197,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.707,-3.927,2.22,,0.121,E,B,0.55,-1.19,0.415,,65.53,HHH,-1.847,0.168804,0.00921295,0.169847 kka2_1:4_H162F,kka2_1:4_162,Kka2,kka2_1:4,P00552,0.169923,NO,162,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-2.319,-4.187,1.868,,0.071,G,A,0.17,1.01,3.187,,64.39,ABP,-2.02067,0.168804,0.00616145,0.169923 kka2_1:2_I221Y,kka2_1:2_221,Kka2,kka2_1:2,P00552,0.169947,NO,221,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.739,-4.012,2.273,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.295029,0.00945908,0.169947 kka2_1:1_D156M,kka2_1:1_156,Kka2,kka2_1:1,P00552,0.169967,NO,156,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.696,-4.858,3.162,,0.884,T,A,0.75,1.87,1.044,,65.53,PAA,-1.765,0.520039,0.00926998,0.169967 beta-lactamase_2500_L120G,beta-lactamase_2500_120,TEM-1,beta-lactamase_2500,P62593,0.169978,NO,120,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.044,-3.788,2.744,,,H,A,0.55,-1.13,2.48,,64.69,AHO,-1.13633,0.361275,0.00143563,0.169978 beta-lactamase_2500_S128W,beta-lactamase_2500_128,TEM-1,beta-lactamase_2500,P62593,0.170005,NO,128,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-0.84,-5.322,4.482,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.361275,0.00071483,0.170005 kka2_1:4_A144M,kka2_1:4_144,Kka2,kka2_1:4,P00552,0.170021,NO,144,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.859,-4.454,3.595,,,H,A,0.46,0.21,6.844,,52.65,BHB,-1.72933,0.168804,0.00231095,0.170021 beta-lactamase_156_K232T,beta-lactamase_156_232,TEM-1,beta-lactamase_156,P62593,0.170028,NO,232,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.012,-3.464,2.452,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.111618,0.00313441,0.170028 kka2_1:4_N195G,kka2_1:4_195,Kka2,kka2_1:4,P00552,0.170061,NO,195,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-0.836,-2.98,2.144,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.168804,0.00276134,0.170061 kka2_1:4_G205T,kka2_1:4_205,Kka2,kka2_1:4,P00552,0.170118,NO,205,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.596,-3.675,3.079,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.168804,0.00221855,0.170118 beta-lactamase_625_G236V,beta-lactamase_625_236,TEM-1,beta-lactamase_625,P62593,0.170261,NO,236,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.784,-3.686,2.902,,0.241,,b,0.29,-0.59,3.506,,64.69,HOO,-1.025,0.213352,0.00162372,0.170261 beta-lactamase_156_L248R,beta-lactamase_156_248,TEM-1,beta-lactamase_156,P62593,0.170269,NO,248,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.111618,0.00428493,0.170269 kka2_1:1_Q136D,kka2_1:1_136,Kka2,kka2_1:1,P00552,0.1703,NO,136,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-3.021,-3.719,0.698,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.520039,0.00624149,0.1703 kka2_1:1_Q27W,kka2_1:1_27,Kka2,kka2_1:1,P00552,0.170356,NO,27,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-1.659,-5.449,3.79,,0.608,.,A,0.64,0.71,0.521,,65.53,PPP,-1.90733,0.520039,0.00595365,0.170356 kka2_1:1_M120S,kka2_1:1_120,Kka2,kka2_1:1,P00552,0.170431,NO,120,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-3.877,-3.662,-0.215,,,H,A,0.55,-0.42,2.259,,92.05,HHB,-2.16733,0.520039,0.00265808,0.170431 kka2_1:1_E149Y,kka2_1:1_149,Kka2,kka2_1:1,P00552,0.170449,NO,149,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.994,-4.359,2.365,,0.674,H,A,1.04,1.63,3.671,,71.59,HAH,-1.59667,0.520039,0.00803343,0.170449 beta-lactamase_625_A230N,beta-lactamase_625_230,TEM-1,beta-lactamase_625,P62593,0.170459,NO,230,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.154,-3.731,2.577,,0.01,E,B,0.46,-1.17,0.777,,50,HHA,-1.079,0.213352,0.00516841,0.170459 beta-lactamase_156_L135P,beta-lactamase_156_135,TEM-1,beta-lactamase_156,P62593,0.170479,NO,135,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.002,-4.134,3.132,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.111618,0.00244423,0.170479 beta-lactamase_2500_L47W,beta-lactamase_2500_47,TEM-1,beta-lactamase_2500,P62593,0.170554,NO,47,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.876,-5.24,3.364,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.361275,0.00439844,0.170554 kka2_1:2_M197F,kka2_1:2_197,Kka2,kka2_1:2,P00552,0.170621,NO,197,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.707,-3.862,2.155,,0.121,E,B,0.55,-1.19,2.097,,65.53,HHH,-1.847,0.295029,0.00921295,0.170621 beta-lactamase_G234Q,beta-lactamase_234,TEM-1,beta-lactamase,P62593,0.170637,NO,234,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.62,-4.124,3.504,4.24221,0.023,E,B,0.46,-0.86,,,,POH,-1.25733,0.221079,0.000889577,0.170637 kka2_1:1_V185T,kka2_1:1_185,Kka2,kka2_1:1,P00552,0.17065,NO,185,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.045,-3.363,2.318,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.520039,0.00367031,0.17065 kka2_1:4_E182R,kka2_1:4_182,Kka2,kka2_1:4,P00552,0.170691,NO,182,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.516,-3.801,2.285,,0.326,.,B,1.04,0.75,4.755,,65.53,OAA,-1.806,0.168804,0.00641548,0.170691 kka2_1:2_V80D,kka2_1:2_80,Kka2,kka2_1:2,P00552,0.170729,NO,80,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.144,-3.971,2.827,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.295029,0.00488211,0.170729 kka2_1:4_D90F,kka2_1:4_90,Kka2,kka2_1:4,P00552,0.17076,NO,90,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.459,-3.305,0.846,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.168804,0.00583842,0.17076 beta-lactamase_156_K232Q,beta-lactamase_156_232,TEM-1,beta-lactamase_156,P62593,0.170858,NO,232,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.012,-3.492,2.48,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.111618,0.00313441,0.170858 beta-lactamase_G242V,beta-lactamase_242,TEM-1,beta-lactamase,P62593,0.170868,NO,242,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.319,-3.713,2.394,4.68003,,E,B,0.87,-1.05,1.079,,50,BOH,-1.428,0.221079,0.00452879,0.170868 kka2_1:2_C131T,kka2_1:2_131,Kka2,kka2_1:2,P00552,0.170896,NO,131,C,T,CT,Special,Polar,5.07,5.6,0.53,149,121,119,-2,108.5,116.1,7.6,-0.831,-3.45,2.619,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.295029,0.00170814,0.170896 beta-lactamase_2500_I280H,beta-lactamase_2500_280,TEM-1,beta-lactamase_2500,P62593,0.170925,NO,280,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.361275,0.0530888,0.170925 beta-lactamase_0_D48H,beta-lactamase_0_48,TEM-1,beta-lactamase_0,P62593,0.170929,NO,48,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.101,-2.659,1.558,,0.189,E,B,0.75,0.21,17.825,17.825,50.35,HAH,-1.62467,0.0500837,0.0027273,0.170929 kka2_1:2_V97P,kka2_1:2_97,Kka2,kka2_1:2,P00552,0.170979,NO,97,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.453,-4.137,2.684,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.295029,0.00737869,0.170979 beta-lactamase_39_I245W,beta-lactamase_39_245,TEM-1,beta-lactamase_39,P62593,0.171008,NO,245,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.0495842,0.00391032,0.171008 beta-lactamase_625_V260P,beta-lactamase_625_260,TEM-1,beta-lactamase_625,P62593,0.171015,NO,260,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.213352,0.00471757,0.171015 kka2_1:2_T187D,kka2_1:2_187,Kka2,kka2_1:2,P00552,0.171039,NO,187,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.273,-3.709,2.436,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.295029,0.00693073,0.171039 kka2_1:2_R226M,kka2_1:2_226,Kka2,kka2_1:2,P00552,0.17104,NO,226,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.392,-4.698,3.306,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.295029,0.0108032,0.17104 beta-lactamase_39_L136R,beta-lactamase_39_136,TEM-1,beta-lactamase_39,P62593,0.171048,NO,136,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.232,-4.116,2.884,,,H,A,0.55,-0.34,0.336,,48.95,HHH,-1.088,0.0495842,0.00442304,0.171048 kka2_1:2_S105N,kka2_1:2_105,Kka2,kka2_1:2,P00552,0.171075,NO,105,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.945,-3.821,1.876,,0.056,S,B,0.27,-1.04,3.442,,65.53,PPB,-2.17033,0.295029,0.00847233,0.171075 kka2_1:1_T187D,kka2_1:1_187,Kka2,kka2_1:1,P00552,0.171079,NO,187,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.273,-3.709,2.436,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.520039,0.00693073,0.171079 kka2_1:2_D220I,kka2_1:2_220,Kka2,kka2_1:2,P00552,0.171094,NO,220,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.787,-3.808,3.021,,,H,A,0.75,-1.14,0.745,,46.59,PAH,-1.152,0.295029,0.00158066,0.171094 beta-lactamase_156_V259Q,beta-lactamase_156_259,TEM-1,beta-lactamase_156,P62593,0.171118,NO,259,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.111618,0.0070773,0.171118 kka2_1:1_G99I,kka2_1:1_99,Kka2,kka2_1:1,P00552,0.171245,NO,99,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.596,-4.264,3.668,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.520039,0.00186055,0.171245 beta-lactamase_2500_A230H,beta-lactamase_2500_230,TEM-1,beta-lactamase_2500,P62593,0.171257,NO,230,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.154,-4.737,3.583,,0.01,E,B,0.46,-1.17,1.171,,50,HHA,-1.079,0.361275,0.00516841,0.171257 kka2_1:8_I29Y,kka2_1:8_29,Kka2,kka2_1:8,P00552,0.171265,NO,29,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.692,-4.24,2.548,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.100394,0.00619521,0.171265 kka2_1:8_I29Y,kka2_1:8_29,Kka2,kka2_1:8,P00552,0.171265,NO,29,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.692,-4.24,2.548,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.100394,0.00619521,0.171265 beta-lactamase_625_M184G,beta-lactamase_625_184,TEM-1,beta-lactamase_625,P62593,0.171269,NO,184,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.593,-3.601,2.008,,,H,A,0.55,-0.87,2.765,,62.94,HHH,-1.41,0.213352,0.00356019,0.171269 kka2_1:4_R121P,kka2_1:4_121,Kka2,kka2_1:4,P00552,0.171289,NO,121,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.552,-4.003,2.451,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.168804,0.00523326,0.171289 kka2_1:1_E96H,kka2_1:1_96,Kka2,kka2_1:1,P00552,0.171316,NO,96,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.573,-4.74,2.167,,0.476,,B,1.52,-0.65,1.254,,71.59,OAH,-2.143,0.520039,0.00369441,0.171316 beta-lactamase_625_L136R,beta-lactamase_625_136,TEM-1,beta-lactamase_625,P62593,0.171336,NO,136,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.232,-4.116,2.884,,,H,A,0.55,-0.34,0.336,,48.95,HHH,-1.088,0.213352,0.00442304,0.171336 kka2_1:2_F133D,kka2_1:2_133,Kka2,kka2_1:2,P00552,0.171383,NO,133,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-0.871,-3.97,3.099,,0.178,.,B,0.58,0.43,1.999,,42.42,OHA,-0.871667,0.295029,0.00182168,0.171383 beta-lactamase_625_L135D,beta-lactamase_625_135,TEM-1,beta-lactamase_625,P62593,0.171389,NO,135,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.002,-4.125,3.123,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.213352,0.00244423,0.171389 beta-lactamase_625_L205R,beta-lactamase_625_205,TEM-1,beta-lactamase_625,P62593,0.171442,NO,205,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.922,-3.987,3.065,,,H,A,0.55,-0.46,3.782,,42.31,PHH,-1.57767,0.213352,0.00255802,0.171442 beta-lactamase_156_Y262G,beta-lactamase_156_262,TEM-1,beta-lactamase_156,P62593,0.171475,NO,262,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.111618,0.00853516,0.171475 kka2_1:2_D208I,kka2_1:2_208,Kka2,kka2_1:2,P00552,0.171527,NO,208,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.708,-4.039,3.331,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.295029,0.00212588,0.171527 E1_Ubiquitin_H70K,E1_Ubiquitin_70,Uba1,E1_Ubiquitin,P0CG63,0.17153,NO,70,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-1.36,,,,0.05,E,B,0.61,-0.97,,,93.18,HBH,-1.146,0.18783,0.00206914,0.17153 beta-lactamase_L205S,beta-lactamase_205,TEM-1,beta-lactamase,P62593,0.171564,NO,205,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.922,-3.629,2.707,5.67023,,H,A,1.3,-0.46,0.678,,42.31,PHH,-1.57767,0.221079,0.00255802,0.171564 beta-lactamase_156_M209R,beta-lactamase_156_209,TEM-1,beta-lactamase_156,P62593,0.171577,NO,209,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.442,-3.939,2.497,,,H,A,0.55,-0.97,1.066,,64.69,HHA,-1.52633,0.111618,0.00625021,0.171577 kka2_1:4_I115H,kka2_1:4_115,Kka2,kka2_1:4,P00552,0.171579,NO,115,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.606,-5.024,3.418,,0.105,H,A,1.52,-1.18,9.996,9.996,65.53,PHH,-2.205,0.168804,0.00836567,0.171579 beta-lactamase_A280P,beta-lactamase_280,TEM-1,beta-lactamase,P62593,0.171586,NO,280,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.708,-3.892,2.184,4.74932,0.379,H,A,0.52,-0.72,1.785,,68.18,OHP,-1.66433,0.221079,0.0530888,0.171586 kka2_1:2_F263Y,kka2_1:2_263,Kka2,kka2_1:2,P00552,0.171639,NO,263,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-0.911,-3.189,2.278,,0.006,G,A,1.62,-0.12,5.275,,45.83,AHH,-0.92,0.295029,0.0172454,0.171639 kka2_1:1_R226W,kka2_1:1_226,Kka2,kka2_1:1,P00552,0.171658,NO,226,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.392,-2.291,0.899,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.520039,0.0108032,0.171658 kka2_1:4_A237K,kka2_1:4_237,Kka2,kka2_1:4,P00552,0.171662,NO,237,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.12,-3.814,1.694,,0.068,H,A,0.46,-0.71,2.444,,92.05,HHA,-2.10433,0.168804,0.012257,0.171662 beta-lactamase_625_L248G,beta-lactamase_625_248,TEM-1,beta-lactamase_625,P62593,0.171677,NO,248,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.794,-3.512,1.718,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.213352,0.00428493,0.171677 beta-lactamase_625_G236P,beta-lactamase_625_236,TEM-1,beta-lactamase_625,P62593,0.171699,NO,236,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.784,-3.879,3.095,,0.241,,b,0.29,-0.59,3.506,,64.69,HOO,-1.025,0.213352,0.00162372,0.171699 beta-lactamase_156_S128M,beta-lactamase_156_128,TEM-1,beta-lactamase_156,P62593,0.171783,NO,128,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-0.84,-4.48,3.64,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.111618,0.00071483,0.171783 beta-lactamase_625_A133F,beta-lactamase_625_133,TEM-1,beta-lactamase_625,P62593,0.171793,NO,133,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.186,-4.224,3.038,,,H,A,0.46,-0.86,0.373,,67.83,HHP,-0.988333,0.213352,0.00468022,0.171793 WW_domain_A180P,WW_domain_180,Yap65,WW_domain,P46937,0.171793,NO,180,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.242,-3.495,2.253,6.02829,,,,,,0.627,,23.61,HHB,-1.37767,0.153962,0.00413929,0.171793 kka2_1:1_L174A,kka2_1:1_174,Kka2,kka2_1:1,P00552,0.171797,NO,174,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.952,-2.507,1.555,,,H,A,0.55,-0.31,13.276,13.276,51.89,BHB,-2.08533,0.520039,0.00438501,0.171797 kka2_1:4_A222N,kka2_1:4_222,Kka2,kka2_1:4,P00552,0.171833,NO,222,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.725,-3.926,3.201,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.168804,0.00207657,0.171833 beta-lactamase_2500_G281P,beta-lactamase_2500_281,TEM-1,beta-lactamase_2500,P62593,0.171852,NO,281,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.361275,0.0406482,0.171852 kka2_1:2_F206A,kka2_1:2_206,Kka2,kka2_1:2,P00552,0.171862,NO,206,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.349,-3.367,2.018,,0.006,E,B,0.58,-1.21,0.978,,63.64,OHH,-1.04,0.295029,0.00936868,0.171862 kka2_1:2_F206N,kka2_1:2_206,Kka2,kka2_1:2,P00552,0.171862,NO,206,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.349,-4.18,2.831,,0.006,E,B,0.58,-1.21,0.978,,63.64,OHH,-1.04,0.295029,0.00936868,0.171862 beta-lactamase_156_G249P,beta-lactamase_156_249,TEM-1,beta-lactamase_156,P62593,0.17187,NO,249,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.312,-2.663,1.351,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.111618,0.00220169,0.17187 kka2_1:1_V75W,kka2_1:1_75,Kka2,kka2_1:1,P00552,0.17187,NO,75,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-2.06,-5.286,3.226,,0.042,.,B,0.44,-0.2,2.815,,71.59,OHO,-1.563,0.520039,0.00693733,0.17187 kka2_1:2_G233A,kka2_1:2_233,Kka2,kka2_1:2,P00552,0.171873,NO,233,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.748,-2.995,2.247,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.295029,0.00232366,0.171873 kka2_1:1_I221W,kka2_1:1_221,Kka2,kka2_1:1,P00552,0.171875,NO,221,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.739,-3.219,1.48,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.520039,0.00945908,0.171875 kka2_1:8_Y22K,kka2_1:8_22,Kka2,kka2_1:8,P00552,0.17188,NO,22,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-1.583,-3.742,2.159,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.100394,0.00598977,0.17188 kka2_1:8_Y22K,kka2_1:8_22,Kka2,kka2_1:8,P00552,0.17188,NO,22,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-1.583,-3.742,2.159,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.100394,0.00598977,0.17188 kka2_1:4_M116D,kka2_1:4_116,Kka2,kka2_1:4,P00552,0.171897,NO,116,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-2.482,-4.161,1.679,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.168804,0.00745147,0.171897 kka2_1:2_L193W,kka2_1:2_193,Kka2,kka2_1:2,P00552,0.171994,NO,193,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.983,-5.198,4.215,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.295029,0.00480179,0.171994 kka2_1:1_V242G,kka2_1:1_242,Kka2,kka2_1:1,P00552,0.171999,NO,242,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-2.687,-3.538,0.851,,0.75,H,A,0.44,-0.37,4.987,,71.59,HHH,-2.16533,0.520039,0.0102575,0.171999 beta-lactamase_M153P,beta-lactamase_153,TEM-1,beta-lactamase,P62593,0.172003,NO,153,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-3.193,-4.07,0.877,5.46509,0.14,T,A,1.07,-0.11,2.061,,77.62,PHO,-2.25767,0.221079,0.00509109,0.172003 beta-lactamase_156_P181R,beta-lactamase_156_181,TEM-1,beta-lactamase_156,P62593,0.172095,NO,181,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.813,-3.93,3.117,,,H,A,0.52,-1.14,1.078,,61.54,HOH,-1.795,0.111618,0.000703122,0.172095 kka2_1:1_G30E,kka2_1:1_30,Kka2,kka2_1:1,P00552,0.172102,NO,30,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.596,-3.693,3.097,,0.54,S,g,0.29,3.76,,,,HOO,-1.51133,0.520039,0.00159208,0.172102 kka2_1:1_V80T,kka2_1:1_80,Kka2,kka2_1:1,P00552,0.17213,NO,80,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.144,-3.381,2.237,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.520039,0.00488211,0.17213 beta-lactamase_2500_R257S,beta-lactamase_2500_257,TEM-1,beta-lactamase_2500,P62593,0.172134,NO,257,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.361275,0.00756629,0.172134 kka2_1:1_L260S,kka2_1:1_260,Kka2,kka2_1:1,P00552,0.172141,NO,260,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.741,-3.639,2.898,,0.022,H,A,0.55,-0.52,,,,HHA,-0.845667,0.520039,0.0233782,0.172141 kka2_1:4_S104W,kka2_1:4_104,Kka2,kka2_1:4,P00552,0.172154,NO,104,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.436,-5.482,4.046,,0.536,T,A,0.27,-1.11,0.357,,63.64,HPP,-1.91433,0.168804,0.00555207,0.172154 beta-lactamase_2500_D129K,beta-lactamase_2500_129,TEM-1,beta-lactamase_2500,P62593,0.172183,NO,129,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.816,-3.42,2.604,,,,B,0.75,-0.69,1.29,,34.97,PAP,-0.818,0.361275,0.00109178,0.172183 kka2_1:1_V186D,kka2_1:1_186,Kka2,kka2_1:1,P00552,0.172226,NO,186,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.011,-4.046,3.035,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.520039,0.00409703,0.172226 beta-lactamase_156_I125E,beta-lactamase_156_125,TEM-1,beta-lactamase_156,P62593,0.172237,NO,125,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.441,-3.878,2.437,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.111618,0.00383964,0.172237 hsp90_W585G,hsp90_585,hsp90,hsp90,P02829,0.172312,NO,585,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-4.251,-2.511,0,5.31455,0.508,,B,1.22,0.43,,,,OHP,-3.17533,0.368192,0.000222939,0.172312 kka2_1:4_V113N,kka2_1:4_113,Kka2,kka2_1:4,P00552,0.172416,NO,113,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.233,-4.251,3.018,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.168804,0.00650191,0.172416 beta-lactamase_625_W227S,beta-lactamase_625_227,TEM-1,beta-lactamase_625,P62593,0.172428,NO,227,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-0.982,-3.768,2.786,,0.272,,B,0.47,-0.29,2.533,,74.48,OHH,-1.595,0.213352,0.00226019,0.172428 beta-lactamase_2500_E62P,beta-lactamase_2500_62,TEM-1,beta-lactamase_2500,P62593,0.172481,NO,62,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.193,-3.775,2.582,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.361275,0.00264802,0.172481 beta-lactamase_2500_L188Q,beta-lactamase_2500_188,TEM-1,beta-lactamase_2500,P62593,0.172484,NO,188,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.166,-4.055,2.889,,,H,A,0.55,-0.3,17.865,17.865,60.14,PHB,-1.47033,0.361275,0.00295687,0.172484 kka2_1:8_G99I,kka2_1:8_99,Kka2,kka2_1:8,P00552,0.172493,NO,99,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.596,-4.264,3.668,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.100394,0.00186055,0.172493 kka2_1:8_G99I,kka2_1:8_99,Kka2,kka2_1:8,P00552,0.172493,NO,99,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.596,-4.264,3.668,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.100394,0.00186055,0.172493 kka2_1:8_Y257N,kka2_1:8_257,Kka2,kka2_1:8,P00552,0.172493,NO,257,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-1.064,-4.053,2.989,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.100394,0.0148191,0.172493 kka2_1:8_Y257N,kka2_1:8_257,Kka2,kka2_1:8,P00552,0.172493,NO,257,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-1.064,-4.053,2.989,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.100394,0.0148191,0.172493 kka2_1:1_Q219D,kka2_1:1_219,Kka2,kka2_1:1,P00552,0.172587,NO,219,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-0.93,-3.333,2.403,,0.088,H,A,0.4,-0.85,1.917,,50,HPA,-1.05167,0.520039,0.00237913,0.172587 kka2_1:1_R217M,kka2_1:1_217,Kka2,kka2_1:1,P00552,0.172608,NO,217,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.158,-4.484,3.326,,0.252,T,A,1.2,-0.59,0.381,,52.27,ABH,-1.127,0.520039,0.0047191,0.172608 beta-lactamase_39_I45P,beta-lactamase_39_45,TEM-1,beta-lactamase_39,P62593,0.172737,NO,45,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-2.421,-4.091,1.67,,,E,B,0.48,-0.3,2.256,,77.62,HHA,-2.30267,0.0495842,0.00452842,0.172737 beta-lactamase_2500_N274W,beta-lactamase_2500_274,TEM-1,beta-lactamase_2500,P62593,0.172757,NO,274,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.361275,0.0110418,0.172757 WW_domain_F189I,WW_domain_189,Yap65,WW_domain,P46937,0.172824,NO,189,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.632,-3.234,1.602,5.47284,,,,,,6.165,,56.94,HHH,-1.454,0.153962,0.00308453,0.172824 kka2_1:8_E199P,kka2_1:8_199,Kka2,kka2_1:8,P00552,0.172902,NO,199,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.234,-4.043,1.809,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.100394,0.00854122,0.172902 kka2_1:8_E199P,kka2_1:8_199,Kka2,kka2_1:8,P00552,0.172902,NO,199,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.234,-4.043,1.809,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.100394,0.00854122,0.172902 kka2_1:8_G189Q,kka2_1:8_189,Kka2,kka2_1:8,P00552,0.172902,NO,189,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.596,-4.153,3.557,,0.034,S,l,0.75,-0.99,,,,BOA,-0.739,0.100394,0.00253688,0.172902 kka2_1:8_G189Q,kka2_1:8_189,Kka2,kka2_1:8,P00552,0.172902,NO,189,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.596,-4.153,3.557,,0.034,S,l,0.75,-0.99,,,,BOA,-0.739,0.100394,0.00253688,0.172902 kka2_1:1_H139C,kka2_1:1_139,Kka2,kka2_1:1,P00552,0.172934,NO,139,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-2.809,-5.201,2.392,,0.471,H,A,0.17,0.68,1.153,,63.64,BBB,-2.22,0.520039,0.00734779,0.172934 beta-lactamase_625_V31G,beta-lactamase_625_31,TEM-1,beta-lactamase_625,P62593,0.172955,NO,31,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.822,-3.699,1.877,,,H,A,0.44,-0.46,2.576,,73.78,BHB,-2.03767,0.213352,0.00478065,0.172955 beta-lactamase_156_E164G,beta-lactamase_156_164,TEM-1,beta-lactamase_156,P62593,0.172956,NO,164,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-0.948,-2.443,1.495,,0.011,T,B,1.04,-0.4,3.445,,64.69,HAO,-1.388,0.111618,0.00137286,0.172956 beta-lactamase_2500_M184G,beta-lactamase_2500_184,TEM-1,beta-lactamase_2500,P62593,0.172979,NO,184,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.593,-3.601,2.008,,,H,A,0.55,-0.87,2.893,,62.94,HHH,-1.41,0.361275,0.00356019,0.172979 beta-lactamase_156_G234T,beta-lactamase_156_234,TEM-1,beta-lactamase_156,P62593,0.172982,NO,234,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.62,-3.646,3.026,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.111618,0.000889577,0.172982 kka2_1:2_F37A,kka2_1:2_37,Kka2,kka2_1:2,P00552,0.172986,NO,37,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.427,-2.571,1.144,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.295029,0.00586193,0.172986 kka2_1:1_L223H,kka2_1:1_223,Kka2,kka2_1:1,P00552,0.17299,NO,223,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.861,-4.978,4.117,,,H,A,0.55,-1.24,1.268,,50,HHH,-0.854333,0.520039,0.00253574,0.17299 kka2_1:1_F206Q,kka2_1:1_206,Kka2,kka2_1:1,P00552,0.173096,NO,206,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.349,-4.252,2.903,,0.006,E,B,0.58,-1.21,0.978,,63.64,OHH,-1.04,0.520039,0.00936868,0.173096 beta-lactamase_625_S233W,beta-lactamase_625_233,TEM-1,beta-lactamase_625,P62593,0.173146,NO,233,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.886,-5.339,3.453,,0.016,E,B,0.27,-1.01,1.773,,77.62,BPO,-1.17267,0.213352,0.00311415,0.173146 kka2_1:2_L232S,kka2_1:2_232,Kka2,kka2_1:2,P00552,0.173158,NO,232,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.514,-3.04,1.526,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.295029,0.00800103,0.173158 kka2_1:1_L94W,kka2_1:1_94,Kka2,kka2_1:1,P00552,0.173189,NO,94,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.618,-5.174,3.556,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.520039,0.00520888,0.173189 beta-lactamase_625_P181F,beta-lactamase_625_181,TEM-1,beta-lactamase_625,P62593,0.173209,NO,181,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.813,-4.48,3.667,,,H,A,0.52,-1.14,1.797,,61.54,HOH,-1.795,0.213352,0.000703122,0.173209 kka2_1:2_L223S,kka2_1:2_223,Kka2,kka2_1:2,P00552,0.173212,NO,223,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.861,-3.684,2.823,,,H,A,0.55,-1.24,0.266,,50,HHH,-0.854333,0.295029,0.00253574,0.173212 beta-lactamase_2500_I206P,beta-lactamase_2500_206,TEM-1,beta-lactamase_2500,P62593,0.173227,NO,206,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-2.429,-4.04,1.611,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.361275,0.00528934,0.173227 beta-lactamase_2500_W288P,beta-lactamase_2500_288,TEM-1,beta-lactamase_2500,P62593,0.173245,NO,288,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,,,,,,,,,,,,,BHO,,0.361275,,0.173245 beta-lactamase_625_V259Q,beta-lactamase_625_259,TEM-1,beta-lactamase_625,P62593,0.173275,NO,259,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.213352,0.0070773,0.173275 kka2_1:1_D208Q,kka2_1:1_208,Kka2,kka2_1:1,P00552,0.173285,NO,208,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.708,-3.703,2.995,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.520039,0.00212588,0.173285 kka2_1:2_V214R,kka2_1:2_214,Kka2,kka2_1:2,P00552,0.173319,NO,214,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.261,-3.109,1.848,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.295029,0.00692782,0.173319 beta-lactamase_2500_D129V,beta-lactamase_2500_129,TEM-1,beta-lactamase_2500,P62593,0.173365,NO,129,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.816,-3.751,2.935,,,,B,0.75,-0.69,1.29,,34.97,PAP,-0.818,0.361275,0.00109178,0.173365 kka2_1:2_G210F,kka2_1:2_210,Kka2,kka2_1:2,P00552,0.173477,NO,210,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.095,-4.324,3.229,,0.103,T,A,0.29,-0.62,0.271,,50,OOB,-0.966667,0.295029,0.00598378,0.173477 kka2_1:2_P194I,kka2_1:2_194,Kka2,kka2_1:2,P00552,0.173478,NO,194,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.846,-4.06,3.214,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.295029,0.00314194,0.173478 kka2_1:4_R44I,kka2_1:4_44,Kka2,kka2_1:4,P00552,0.173478,NO,44,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.062,-4.031,1.969,,0.487,S,B,1.2,-0.35,5.71,,71.59,OBO,-1.80767,0.168804,0.00745043,0.173478 kka2_1:2_F171N,kka2_1:2_171,Kka2,kka2_1:2,P00552,0.173511,NO,171,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.326,-4.165,2.839,,0.154,H,A,0.58,-0.1,2.645,,63.64,HHH,-1.45433,0.295029,0.00821426,0.173511 beta-lactamase_2500_V259K,beta-lactamase_2500_259,TEM-1,beta-lactamase_2500,P62593,0.173513,NO,259,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.361275,0.0070773,0.173513 beta-lactamase_2500_L136W,beta-lactamase_2500_136,TEM-1,beta-lactamase_2500,P62593,0.173542,NO,136,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.232,-5.281,4.049,,,H,A,0.55,-0.34,1.36,,48.95,HHH,-1.088,0.361275,0.00442304,0.173542 kka2_1:2_L241W,kka2_1:2_241,Kka2,kka2_1:2,P00552,0.173569,NO,241,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.158,-4.909,3.751,,0.08,H,A,0.55,-0.82,1.598,,63.26,HHH,-1.58533,0.295029,0.0117299,0.173569 kka2_1:1_V46R,kka2_1:1_46,Kka2,kka2_1:1,P00552,0.173636,NO,46,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-2.62,-2.74,0.12,,0.192,.,B,0.44,-1.12,20.149,20.149,92.05,OHH,-1.88633,0.520039,0.00631301,0.173636 kka2_1:2_E182S,kka2_1:2_182,Kka2,kka2_1:2,P00552,0.173661,NO,182,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.516,-3.382,1.866,,0.326,,B,1.52,0.75,14.547,14.547,65.53,OAA,-1.806,0.295029,0.00641548,0.173661 kka2_1:1_D208S,kka2_1:1_208,Kka2,kka2_1:1,P00552,0.173685,NO,208,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.708,-3.189,2.481,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.520039,0.00212588,0.173685 beta-lactamase_2500_V31K,beta-lactamase_2500_31,TEM-1,beta-lactamase_2500,P62593,0.173805,NO,31,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.822,-3.873,2.051,,,H,A,0.44,-0.46,0.955,,73.78,BHB,-2.03767,0.361275,0.00478065,0.173805 beta-lactamase_2500_F70K,beta-lactamase_2500_70,TEM-1,beta-lactamase_2500,P62593,0.173819,NO,70,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.169,-3.812,2.643,,,H,A,0.58,-1.34,1.918,,63.99,PHB,-0.980667,0.361275,0.00193499,0.173819 beta-lactamase_156_K71T,beta-lactamase_156_71,TEM-1,beta-lactamase_156,P62593,0.173949,NO,71,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-0.8,-3.421,2.621,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.111618,0.00103192,0.173949 beta-lactamase_M1C,beta-lactamase_1,TEM-1,beta-lactamase,P62593,0.173954,NO,1,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.998,-4.319,2.321,,,,,,,,,,OHP,-1.97,0.221079,0.00162771,0.173954 beta-lactamase_156_G240I,beta-lactamase_156_240,TEM-1,beta-lactamase_156,P62593,0.173985,NO,240,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.111618,0.00591201,0.173985 kka2_1:2_H162E,kka2_1:2_162,Kka2,kka2_1:2,P00552,0.17399,NO,162,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-2.319,-3.397,1.078,,0.071,G,A,0.17,1.01,3.187,,64.39,ABP,-2.02067,0.295029,0.00616145,0.17399 beta-lactamase_S233H,beta-lactamase_233,TEM-1,beta-lactamase,P62593,0.174108,NO,233,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.886,-4.67,2.784,4.98121,0.016,E,B,0.48,-1.01,5.361,,77.62,BPO,-1.17267,0.221079,0.00311415,0.174108 beta-lactamase_2500_K71E,beta-lactamase_2500_71,TEM-1,beta-lactamase_2500,P62593,0.174126,NO,71,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-0.8,-2.99,2.19,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.361275,0.00103192,0.174126 kka2_1:1_V113Q,kka2_1:1_113,Kka2,kka2_1:1,P00552,0.174234,NO,113,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.233,-4.296,3.063,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.520039,0.00650191,0.174234 beta-lactamase_625_R257P,beta-lactamase_625_257,TEM-1,beta-lactamase_625,P62593,0.174247,NO,257,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.213352,0.00756629,0.174247 kka2_1:1_R239W,kka2_1:1_239,Kka2,kka2_1:1,P00552,0.174274,NO,239,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.949,-5.592,2.643,,0.15,H,A,1.2,-0.31,0.477,,71.59,ABH,-2.23,0.520039,0.00835326,0.174274 beta-lactamase_2500_N274K,beta-lactamase_2500_274,TEM-1,beta-lactamase_2500,P62593,0.174294,NO,274,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.361275,0.0110418,0.174294 kka2_1:1_L223G,kka2_1:1_223,Kka2,kka2_1:1,P00552,0.174335,NO,223,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.861,-3.881,3.02,,,H,A,0.55,-1.24,1.268,,50,HHH,-0.854333,0.520039,0.00253574,0.174335 beta-lactamase_625_L191R,beta-lactamase_625_191,TEM-1,beta-lactamase_625,P62593,0.174346,NO,191,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.087,-4.02,2.933,,,H,A,0.55,0.09,1.908,,63.29,BHH,-1.445,0.213352,0.00263549,0.174346 beta-lactamase_156_D129I,beta-lactamase_156_129,TEM-1,beta-lactamase_156,P62593,0.174368,NO,129,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.816,-4.036,3.22,,,,B,0.75,-0.69,1.924,,34.97,PAP,-0.818,0.111618,0.00109178,0.174368 kka2_1:1_W236E,kka2_1:1_236,Kka2,kka2_1:1,P00552,0.174433,NO,236,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-1.363,-3.989,2.626,,0.303,H,A,1.51,-0.76,12.263,12.263,48.48,AHH,-1.81267,0.520039,0.0088796,0.174433 kka2_1:1_F256D,kka2_1:1_256,Kka2,kka2_1:1,P00552,0.174527,NO,256,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.49,-4.089,2.599,,,H,A,1.62,-0.78,2.354,,53.03,HHH,-1.423,0.520039,0.0132841,0.174527 beta-lactamase_2500_T27Y,beta-lactamase_2500_27,TEM-1,beta-lactamase_2500,P62593,0.174543,NO,27,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.905,-4.144,2.239,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.361275,0.00306559,0.174543 beta-lactamase_V257Q,beta-lactamase_257,TEM-1,beta-lactamase,P62593,0.174547,NO,257,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.533,-4.23,2.697,5.31999,,E,B,0.96,-0.7,1.463,,58.74,HHH,-1.70967,0.221079,0.00756629,0.174547 beta-lactamase_I283D,beta-lactamase_283,TEM-1,beta-lactamase,P62593,0.174594,NO,283,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.638,-3.947,2.309,5.4178,0.165,H,A,1.23,0.04,1.576,,69.23,HHB,-1.735,0.221079,0.0429138,0.174594 beta-lactamase_625_S233N,beta-lactamase_625_233,TEM-1,beta-lactamase_625,P62593,0.174606,NO,233,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.886,-2.73,0.844,,0.016,E,B,0.27,-1.01,1.773,,77.62,BPO,-1.17267,0.213352,0.00311415,0.174606 beta-lactamase_2500_I285D,beta-lactamase_2500_285,TEM-1,beta-lactamase_2500,P62593,0.174625,NO,285,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.361275,0.101555,0.174625 beta-lactamase_2500_A40H,beta-lactamase_2500_40,TEM-1,beta-lactamase_2500,P62593,0.174633,NO,40,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.402,-4.792,3.39,,0.155,S,B,0.46,0.21,0.953,,73.78,OHB,-1.40267,0.361275,0.00490026,0.174633 kka2_1:1_G233A,kka2_1:1_233,Kka2,kka2_1:1,P00552,0.174655,NO,233,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.748,-2.995,2.247,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.520039,0.00232366,0.174655 kka2_1:1_Y218T,kka2_1:1_218,Kka2,kka2_1:1,P00552,0.174655,NO,218,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-1.438,-3.77,2.332,,0.122,H,A,1.25,-0.69,3.059,,56.06,BHP,-1.17533,0.520039,0.0126098,0.174655 beta-lactamase_2500_T107Y,beta-lactamase_2500_107,TEM-1,beta-lactamase_2500,P62593,0.174672,NO,107,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.117,-4.214,3.097,,,G,A,0.22,-0.06,2.686,,67.83,HPA,-1.265,0.361275,0.00239347,0.174672 beta-lactamase_2500_A185E,beta-lactamase_2500_185,TEM-1,beta-lactamase_2500,P62593,0.174681,NO,185,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.406,-3.679,2.273,,,H,A,0.46,-1.02,2.999,,65.03,HHP,-1.84033,0.361275,0.00467449,0.174681 kka2_1:1_Y22K,kka2_1:1_22,Kka2,kka2_1:1,P00552,0.174686,NO,22,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-1.583,-3.742,2.159,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.520039,0.00598977,0.174686 kka2_1:8_C77M,kka2_1:8_77,Kka2,kka2_1:8,P00552,0.174733,NO,77,C,M,CM,Special,Hydrophobic,5.07,5.74,0.67,196,121,149,28,108.5,162.9,54.4,-1.477,-4.643,3.166,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.100394,0.00441216,0.174733 kka2_1:8_C77M,kka2_1:8_77,Kka2,kka2_1:8,P00552,0.174733,NO,77,C,M,CM,Special,Hydrophobic,5.07,5.74,0.67,196,121,149,28,108.5,162.9,54.4,-1.477,-4.643,3.166,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.100394,0.00441216,0.174733 kka2_1:1_D220W,kka2_1:1_220,Kka2,kka2_1:1,P00552,0.174745,NO,220,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.787,-5.574,4.787,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.520039,0.00158066,0.174745 kka2_1:1_K175S,kka2_1:1_175,Kka2,kka2_1:1,P00552,0.174814,NO,175,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-2.897,-3.083,0.186,,0.579,H,A,1.3,0.51,9.33,9.33,71.59,HBH,-1.82333,0.520039,0.00693093,0.174814 kka2_1:4_D33I,kka2_1:4_33,Kka2,kka2_1:4,P00552,0.174833,NO,33,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.186,-4.175,1.989,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.168804,0.00633568,0.174833 beta-lactamase_W208R,beta-lactamase_208,TEM-1,beta-lactamase,P62593,0.174895,NO,208,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-0.818,-4.158,3.34,5.26277,0.067,H,A,0.99,-0.65,,,,AHH,-1.44133,0.221079,0.00126609,0.174895 beta-lactamase_2500_V78D,beta-lactamase_2500_78,TEM-1,beta-lactamase_2500,P62593,0.174959,NO,78,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.459,-4.082,2.623,,,H,A,0.44,-0.47,31.376,31.376,63.64,HHH,-1.17833,0.361275,0.00492501,0.174959 beta-lactamase_625_T69W,beta-lactamase_625_69,TEM-1,beta-lactamase_625,P62593,0.174964,NO,69,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-0.973,-5.208,4.235,,,G,A,0.22,-1.24,2.716,,93.01,PPH,-1.01833,0.213352,0.00127498,0.174964 kka2_1:2_I115G,kka2_1:2_115,Kka2,kka2_1:2,P00552,0.174974,NO,115,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.606,-3.814,2.208,,0.105,H,A,0.48,-1.18,0.878,,65.53,PHH,-2.205,0.295029,0.00836567,0.174974 kka2_1:2_H124G,kka2_1:2_124,Kka2,kka2_1:2,P00552,0.174978,NO,124,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-0.84,-3.386,2.546,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.295029,0.00211296,0.174978 beta-lactamase_2500_L248Y,beta-lactamase_2500_248,TEM-1,beta-lactamase_2500,P62593,0.174994,NO,248,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.361275,0.00428493,0.174994 beta-lactamase_625_W227C,beta-lactamase_625_227,TEM-1,beta-lactamase_625,P62593,0.175165,NO,227,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-0.982,-4.932,3.95,,0.272,,B,0.47,-0.29,2.533,,74.48,OHH,-1.595,0.213352,0.00226019,0.175165 kka2_1:1_L193T,kka2_1:1_193,Kka2,kka2_1:1,P00552,0.175181,NO,193,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.983,-3.533,2.55,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.520039,0.00480179,0.175181 kka2_1:1_A41Y,kka2_1:1_41,Kka2,kka2_1:1,P00552,0.175194,NO,41,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.879,-4.263,2.384,,0.184,.,B,0.46,-0.96,18.207,18.207,64.39,PHP,-2.477,0.520039,0.00543332,0.175194 Pab1_V171Y,Pab1_171,Pab1,Pab1,P04147,0.17521,NO,171,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.113,-3.755,2.642,,0.008,E,b,0.23,-0.34,,,,HHB,-1.19733,0.175299,0.000298662,0.17521 kka2_1:1_D216Q,kka2_1:1_216,Kka2,kka2_1:1,P00552,0.175262,NO,216,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.785,-3.726,2.941,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.520039,0.00229969,0.175262 kka2_1:2_P45Y,kka2_1:2_45,Kka2,kka2_1:2,P00552,0.175399,NO,45,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.774,-4.485,2.711,,0.669,,B,0.52,-0.76,4.882,,71.59,BOH,-2.152,0.295029,0.00590481,0.175399 beta-lactamase_156_I125R,beta-lactamase_156_125,TEM-1,beta-lactamase_156,P62593,0.175424,NO,125,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.441,-4.126,2.685,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.111618,0.00383964,0.175424 beta-lactamase_2500_G142Y,beta-lactamase_2500_142,TEM-1,beta-lactamase_2500,P62593,0.175431,NO,142,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.707,-4.385,3.678,,0.034,,p,0.29,-0.64,1.883,,64.69,OOO,-0.834,0.361275,0.00060149,0.175431 kka2_1:1_I196Y,kka2_1:1_196,Kka2,kka2_1:1,P00552,0.175455,NO,196,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-2.115,-2.902,0.787,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.520039,0.0107273,0.175455 beta-lactamase_625_G76R,beta-lactamase_625_76,TEM-1,beta-lactamase_625,P62593,0.175505,NO,76,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.189,-3.905,2.716,,,H,A,0.29,-0.67,3.059,,67.83,OOH,-1.22267,0.213352,0.00476637,0.175505 beta-lactamase_G236Y,beta-lactamase_236,TEM-1,beta-lactamase,P62593,0.175516,NO,236,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.784,-4.387,3.603,4.7915,0.241,,b,0.23,-0.59,1.883,,64.69,HOA,-1.36933,0.221079,0.00162372,0.175516 kka2_1:4_D101E,kka2_1:4_101,Kka2,kka2_1:4,P00552,0.175516,NO,101,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.028,-3.074,2.046,,0.213,E,B,0.75,-1.24,8.707,,63.64,PAH,-1.534,0.168804,0.00423361,0.175516 kka2_1:1_A79F,kka2_1:1_79,Kka2,kka2_1:1,P00552,0.175524,NO,79,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.368,-4.451,2.083,,0.563,.,B,0.46,-0.43,7.792,7.792,71.59,HHH,-1.752,0.520039,0.00664821,0.175524 beta-lactamase_625_L47D,beta-lactamase_625_47,TEM-1,beta-lactamase_625,P62593,0.175528,NO,47,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.876,-3.931,2.055,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.213352,0.00439844,0.175528 kka2_1:2_V153K,kka2_1:2_153,Kka2,kka2_1:2,P00552,0.17553,NO,153,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.092,-3.83,2.738,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.295029,0.00501119,0.17553 kka2_1:4_D216F,kka2_1:4_216,Kka2,kka2_1:4,P00552,0.175565,NO,216,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.785,-4.288,3.503,,0.018,E,B,0.75,-0.51,0.112,,19.32,HAB,-0.970333,0.168804,0.00229969,0.175565 beta-lactamase_156_G76E,beta-lactamase_156_76,TEM-1,beta-lactamase_156,P62593,0.175592,NO,76,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.189,-3.614,2.425,,,H,A,0.29,-0.67,3.059,,67.83,OOH,-1.22267,0.111618,0.00476637,0.175592 beta-lactamase_2500_L205E,beta-lactamase_2500_205,TEM-1,beta-lactamase_2500,P62593,0.175615,NO,205,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.922,-3.908,2.986,,,H,A,0.55,-0.46,0.831,,42.31,PHH,-1.57767,0.361275,0.00255802,0.175615 beta-lactamase_156_A124F,beta-lactamase_156_124,TEM-1,beta-lactamase_156,P62593,0.175668,NO,124,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.181,-4.133,2.952,,,H,A,0.46,-0.9,2.027,,64.34,HHH,-1.152,0.111618,0.00481399,0.175668 beta-lactamase_2500_I258N,beta-lactamase_2500_258,TEM-1,beta-lactamase_2500,P62593,0.175721,NO,258,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.361275,0.007931,0.175721 kka2_1:4_L193E,kka2_1:4_193,Kka2,kka2_1:4,P00552,0.175776,NO,193,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.983,-3.783,2.8,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.168804,0.00480179,0.175776 kka2_1:1_A144Q,kka2_1:1_144,Kka2,kka2_1:1,P00552,0.175792,NO,144,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.859,-4.01,3.151,,,H,A,0.46,0.21,0.842,,52.65,BHB,-1.72933,0.520039,0.00231095,0.175792 kka2_1:4_C77D,kka2_1:4_77,Kka2,kka2_1:4,P00552,0.175825,NO,77,C,D,CD,Special,negativeCharge,5.07,5.0516,-0.0184,154,121,133,12,108.5,111.1,2.6,-1.477,-3.887,2.41,,0.229,B,b,0.46,-0.57,2.499,,63.26,OOH,-1.55667,0.168804,0.00441216,0.175825 kka2_1:1_G245Y,kka2_1:1_245,Kka2,kka2_1:1,P00552,0.175827,NO,245,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.812,-4.419,3.607,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.520039,0.00683899,0.175827 kka2_1:4_F263G,kka2_1:4_263,Kka2,kka2_1:4,P00552,0.175829,NO,263,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-0.911,-3.675,2.764,,0.006,G,A,0.58,-0.12,2.284,,45.83,AHH,-0.92,0.168804,0.0172454,0.175829 beta-lactamase_2500_G234Y,beta-lactamase_2500_234,TEM-1,beta-lactamase_2500,P62593,0.175885,NO,234,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.62,-4.387,3.767,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.361275,0.000889577,0.175885 beta-lactamase_2500_L192G,beta-lactamase_2500_192,TEM-1,beta-lactamase_2500,P62593,0.175893,NO,192,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.254,-3.698,2.444,,0.095,H,A,0.55,0.35,1.902,,60.14,HHP,-1.41833,0.361275,0.00558728,0.175893 kka2_1:8_I207S,kka2_1:8_207,Kka2,kka2_1:8,P00552,0.175948,NO,207,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.175,-3.726,2.551,,0.293,,B,1.52,-1.12,1.306,,56.06,HHA,-1.07733,0.100394,0.00611824,0.175948 kka2_1:8_I207S,kka2_1:8_207,Kka2,kka2_1:8,P00552,0.175948,NO,207,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.175,-3.726,2.551,,0.293,,B,1.52,-1.12,1.306,,56.06,HHA,-1.07733,0.100394,0.00611824,0.175948 kka2_1:1_D227I,kka2_1:1_227,Kka2,kka2_1:1,P00552,0.175953,NO,227,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.758,-3.917,2.159,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.520039,0.00745029,0.175953 beta-lactamase_2500_L192K,beta-lactamase_2500_192,TEM-1,beta-lactamase_2500,P62593,0.175974,NO,192,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.254,-3.803,2.549,,0.095,H,A,0.55,0.35,1.902,,60.14,HHP,-1.41833,0.361275,0.00558728,0.175974 beta-lactamase_39_G243I,beta-lactamase_39_243,TEM-1,beta-lactamase_39,P62593,0.176002,NO,243,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.532,-3.58,2.048,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.0495842,0.00464034,0.176002 kka2_1:2_Y218K,kka2_1:2_218,Kka2,kka2_1:2,P00552,0.176002,NO,218,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-1.438,-3.819,2.381,,0.122,H,A,0.21,-0.69,1.022,,56.06,BHP,-1.17533,0.295029,0.0126098,0.176002 beta-lactamase_Y95E,beta-lactamase_95,TEM-1,beta-lactamase,P62593,0.176048,NO,95,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-1.715,-3.911,2.196,5.67068,0.122,,b,0.96,-0.37,2.341,,77.62,BHP,-2.16167,0.221079,0.00479449,0.176048 kka2_1:2_D190S,kka2_1:2_190,Kka2,kka2_1:2,P00552,0.176069,NO,190,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.708,-3.189,2.481,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.295029,0.00247989,0.176069 kka2_1:8_H135E,kka2_1:8_135,Kka2,kka2_1:8,P00552,0.17615,NO,135,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-1.331,-3.297,1.966,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.100394,0.00532566,0.17615 kka2_1:8_H135E,kka2_1:8_135,Kka2,kka2_1:8,P00552,0.17615,NO,135,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-1.331,-3.297,1.966,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.100394,0.00532566,0.17615 kka2_1:2_Y22R,kka2_1:2_22,Kka2,kka2_1:2,P00552,0.176327,NO,22,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-1.583,-3.13,1.547,,0.122,.,B,0.21,-0.8,1.838,,65.53,OHA,-1.80333,0.295029,0.00598977,0.176327 beta-lactamase_625_A132H,beta-lactamase_625_132,TEM-1,beta-lactamase_625,P62593,0.176348,NO,132,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.9,-4.724,3.824,,,H,A,0.46,-0.93,0.316,,64.69,PHH,-1.138,0.213352,0.000962524,0.176348 kka2_1:1_S204K,kka2_1:1_204,Kka2,kka2_1:1,P00552,0.176374,NO,204,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.353,-3.511,2.158,,0.144,E,A,0.27,-1.2,3.022,,65.53,HPO,-0.953333,0.520039,0.00881794,0.176374 beta-lactamase_39_E62P,beta-lactamase_39_62,TEM-1,beta-lactamase_39,P62593,0.176376,NO,62,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.193,-3.775,2.582,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.0495842,0.00264802,0.176376 beta-lactamase_156_E164H,beta-lactamase_156_164,TEM-1,beta-lactamase_156,P62593,0.176384,NO,164,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-0.948,-4.339,3.391,,0.011,T,B,1.04,-0.4,3.445,,64.69,HAO,-1.388,0.111618,0.00137286,0.176384 beta-lactamase_2500_I258T,beta-lactamase_2500_258,TEM-1,beta-lactamase_2500,P62593,0.17641,NO,258,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.361275,0.007931,0.17641 beta-lactamase_625_L188K,beta-lactamase_625_188,TEM-1,beta-lactamase_625,P62593,0.17641,NO,188,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.166,-3.695,2.529,,,H,A,0.55,-0.3,2.982,,60.14,PHB,-1.47033,0.213352,0.00295687,0.17641 kka2_1:1_F203M,kka2_1:1_203,Kka2,kka2_1:1,P00552,0.176453,NO,203,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-0.911,-4.239,3.328,,0.26,E,B,0.58,-0.92,7.323,,63.64,BHP,-1.34167,0.520039,0.00318738,0.176453 beta-lactamase_625_M209S,beta-lactamase_625_209,TEM-1,beta-lactamase_625,P62593,0.176532,NO,209,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.442,-3.579,2.137,,,H,A,0.55,-0.97,1.167,,64.69,HHA,-1.52633,0.213352,0.00625021,0.176532 beta-lactamase_156_S128R,beta-lactamase_156_128,TEM-1,beta-lactamase_156,P62593,0.176581,NO,128,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-0.84,-3.708,2.868,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.111618,0.00071483,0.176581 beta-lactamase_625_A230D,beta-lactamase_625_230,TEM-1,beta-lactamase_625,P62593,0.176624,NO,230,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.154,-3.645,2.491,,0.01,E,B,0.46,-1.17,0.777,,50,HHA,-1.079,0.213352,0.00516841,0.176624 kka2_1:1_A65W,kka2_1:1_65,Kka2,kka2_1:1,P00552,0.176658,NO,65,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.744,-5.541,3.797,,0.437,H,A,0.46,-0.39,3.012,,63.64,HHB,-1.38733,0.520039,0.00709258,0.176658 kka2_1:2_L126H,kka2_1:2_126,Kka2,kka2_1:2,P00552,0.176681,NO,126,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.246,-4.997,3.751,,0.285,S,B,0.55,0.12,1.392,,51.89,PHA,-1.744,0.295029,0.0066485,0.176681 kka2_1:1_C192N,kka2_1:1_192,Kka2,kka2_1:1,P00552,0.176732,NO,192,C,N,CN,Special,Polar,5.07,5.47157,0.401575,139,121,132,11,108.5,114.1,5.6,-1.067,-3.983,2.916,,0.095,.,B,0.46,-0.75,2.749,,50,HOH,-0.960333,0.520039,0.00485428,0.176732 beta-lactamase_2500_L284W,beta-lactamase_2500_284,TEM-1,beta-lactamase_2500,P62593,0.176766,NO,284,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.361275,0.0686156,0.176766 beta-lactamase_2500_Y262N,beta-lactamase_2500_262,TEM-1,beta-lactamase_2500,P62593,0.176771,NO,262,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.361275,0.00853516,0.176771 gb1_A249W,gb1_249,gb1,gb1,P06654,0.176779,NO,249,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.739,-5.2,3.461,,,,,,,0.252,,44.87,AHH,-1.67367,0.177985,0.00333585,0.176779 gb1_A252D,gb1_252,gb1,gb1,P06654,0.176779,NO,252,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.175,-3.429,2.254,,,,,,,,,,PHA,-1.55967,0.177985,0.00125598,0.176779 gb1_A260N,gb1_260,gb1,gb1,P06654,0.176779,NO,260,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.486,-3.87,2.384,,,,,,,0.173,,9.6,HHP,-1.70967,0.177985,0.0055808,0.176779 gb1_F256P,gb1_256,gb1,gb1,P06654,0.176779,NO,256,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.241,-4.107,2.866,,,,,,,,,,HHB,-2.04767,0.177985,0.00435993,0.176779 gb1_F278S,gb1_278,gb1,gb1,P06654,0.176779,NO,278,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.418,-3.3,1.882,,,,,,,3.233,,35.71,PHP,-1.503,0.177985,0.00295699,0.176779 gb1_G267E,gb1_267,gb1,gb1,P06654,0.176779,NO,267,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.676,-3.587,1.911,,,,,,,1.361,,12.72,AOA,-1.61833,0.177985,0.00264655,0.176779 gb1_G267W,gb1_267,gb1,gb1,P06654,0.176779,NO,267,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.676,-4.829,3.153,,,,,,,1.361,,12.72,AOA,-1.61833,0.177985,0.00264655,0.176779 gb1_K257L,gb1_257,gb1,gb1,P06654,0.176779,NO,257,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.775,-3.247,1.472,,,,,,,0.896,,37.28,HBP,-1.70367,0.177985,0.00640304,0.176779 gb1_N263P,gb1_263,gb1,gb1,P06654,0.176779,NO,263,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-1.162,-3.657,2.495,,,,,,,,,,APO,-2.04233,0.177985,0.0035297,0.176779 gb1_V265D,gb1_265,gb1,gb1,P06654,0.176779,NO,265,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.843,-3.54,1.697,,,,,,,0.402,,11.83,OHA,-1.64567,0.177985,0.00360613,0.176779 beta-lactamase_2500_D161W,beta-lactamase_2500_161,TEM-1,beta-lactamase_2500,P62593,0.17679,NO,161,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.891,-5.546,4.655,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.361275,0.000897697,0.17679 kka2_1:1_L212A,kka2_1:1_212,Kka2,kka2_1:1,P00552,0.176802,NO,212,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.904,-2.253,1.349,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.520039,0.0031426,0.176802 beta-lactamase_E164K,beta-lactamase_164,TEM-1,beta-lactamase,P62593,0.176812,NO,164,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-0.948,-2.425,1.477,5.3334,0.011,T,B,1.62,-0.4,1.055,,64.69,HAO,-1.388,0.221079,0.00137286,0.176812 E1_Ubiquitin_G75V,E1_Ubiquitin_75,Uba1,E1_Ubiquitin,P0CG63,0.176835,NO,75,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.999,-3.624,2.625,,0.552,T,A,0.75,0.9,4.369,,83.73,BOO,-1.1,0.18783,0.00153276,0.176835 beta-lactamase_0_G76F,beta-lactamase_0_76,TEM-1,beta-lactamase_0,P62593,0.176846,NO,76,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.189,-4.264,3.075,,,H,A,0.29,-0.67,1.188,,67.83,OOH,-1.22267,0.0500837,0.00476637,0.176846 beta-lactamase_2500_M209N,beta-lactamase_2500_209,TEM-1,beta-lactamase_2500,P62593,0.176862,NO,209,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.442,-4.092,2.65,,,H,A,0.55,-0.97,3.229,,64.69,HHA,-1.52633,0.361275,0.00625021,0.176862 beta-lactamase_625_V31H,beta-lactamase_625_31,TEM-1,beta-lactamase_625,P62593,0.176866,NO,31,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.822,-4.968,3.146,,,H,A,0.44,-0.46,2.576,,73.78,BHB,-2.03767,0.213352,0.00478065,0.176866 beta-lactamase_625_D177V,beta-lactamase_625_177,TEM-1,beta-lactamase_625,P62593,0.176902,NO,177,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.967,-3.739,2.772,,0.006,T,L,0.75,-1.02,1.333,,64.69,BAP,-0.873667,0.213352,0.000864022,0.176902 kka2_1:2_D261R,kka2_1:2_261,Kka2,kka2_1:2,P00552,0.176918,NO,261,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.708,-3.961,3.253,,0.146,G,A,0.75,-0.33,,,,HAA,-0.759333,0.295029,0.0224846,0.176918 beta-lactamase_2500_I244N,beta-lactamase_2500_244,TEM-1,beta-lactamase_2500,P62593,0.176938,NO,244,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.555,-4.114,2.559,,,E,B,0.48,-0.84,1.683,,77.62,OHH,-1.385,0.361275,0.00605379,0.176938 kka2_1:4_A117D,kka2_1:4_117,Kka2,kka2_1:4,P00552,0.176988,NO,117,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.828,-3.786,2.958,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.168804,0.00282984,0.176988 beta-lactamase_39_D177L,beta-lactamase_39_177,TEM-1,beta-lactamase_39,P62593,0.177107,NO,177,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.967,-3.772,2.805,,0.006,T,L,0.75,-1.02,3.536,,64.69,BAP,-0.873667,0.0495842,0.000864022,0.177107 kka2_1:8_V198P,kka2_1:8_198,Kka2,kka2_1:8,P00552,0.177159,NO,198,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.719,-3.911,2.192,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.100394,0.00835002,0.177159 kka2_1:8_V198P,kka2_1:8_198,Kka2,kka2_1:8,P00552,0.177159,NO,198,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.719,-3.911,2.192,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.100394,0.00835002,0.177159 beta-lactamase_625_L167D,beta-lactamase_625_167,TEM-1,beta-lactamase_625,P62593,0.177204,NO,167,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.138,-4.03,2.892,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.213352,0.00303566,0.177204 beta-lactamase_625_E164C,beta-lactamase_625_164,TEM-1,beta-lactamase_625,P62593,0.177213,NO,164,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-0.948,-5.311,4.363,,0.011,T,B,1.04,-0.4,1.321,,64.69,HAO,-1.388,0.213352,0.00137286,0.177213 beta-lactamase_156_E164S,beta-lactamase_156_164,TEM-1,beta-lactamase_156,P62593,0.177248,NO,164,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-0.948,-3.21,2.262,,0.011,T,B,1.04,-0.4,3.445,,64.69,HAO,-1.388,0.111618,0.00137286,0.177248 beta-lactamase_A235W,beta-lactamase_235,TEM-1,beta-lactamase,P62593,0.177324,NO,235,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.266,-5.379,4.113,4.83024,0.32,E,B,0.52,-0.86,1.344,,50,OHO,-0.89,0.221079,0.00493474,0.177324 Ubiquitin_K48L,Ubiquitin_48,Uba1,Ubiquitin,P0CG48,0.177419,NO,48,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.436,-3.364,1.928,5.03072,0.132,E,B,2.92,-0.28,1.539,,53.87,OBP,-1.6,0.205827,0.000394633,0.177419 Ubiquitin_K48T,Ubiquitin_48,Uba1,Ubiquitin,P0CG48,0.177419,NO,48,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.436,-3.475,2.039,5.03072,0.132,E,B,2.92,-0.28,1.539,,53.87,OBP,-1.6,0.205827,0.000394633,0.177419 Ubiquitin_L69E,Ubiquitin_69,Uba1,Ubiquitin,P0CG48,0.177419,NO,69,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.445,-3.691,2.246,4.75624,0.051,E,B,2.89,-0.94,7.106,,34.31,BHH,-1.72933,0.205827,0.000919136,0.177419 Ubiquitin_L71C,Ubiquitin_71,Uba1,Ubiquitin,P0CG48,0.177419,NO,71,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.647,-4.932,3.285,5.02588,0.591,E,B,2.89,-0.69,4.365,,34.31,HHB,-1.85167,0.205827,0.000949314,0.177419 Ubiquitin_R72W,Ubiquitin_72,Uba1,Ubiquitin,P0CG48,0.177419,NO,72,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.034,-5.348,3.314,5.19484,0.077,,B,1.41,-0.1,9.638,9.638,42.77,HBH,-1.82733,0.205827,0.000768249,0.177419 beta-lactamase_2500_W227D,beta-lactamase_2500_227,TEM-1,beta-lactamase_2500,P62593,0.177452,NO,227,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-0.982,-4.076,3.094,,0.272,,B,0.47,-0.29,1.37,,74.48,OHH,-1.595,0.361275,0.00226019,0.177452 beta-lactamase_625_L74P,beta-lactamase_625_74,TEM-1,beta-lactamase_625,P62593,0.177455,NO,74,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.296,-4.001,2.705,,,H,A,0.55,-0.91,0.895,,50,HHO,-1.34933,0.213352,0.00493255,0.177455 beta-lactamase_2500_L120P,beta-lactamase_2500_120,TEM-1,beta-lactamase_2500,P62593,0.177456,NO,120,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.044,-4.17,3.126,,,H,A,0.55,-1.13,2.48,,64.69,AHO,-1.13633,0.361275,0.00143563,0.177456 kka2_1:1_L123Q,kka2_1:1_123,Kka2,kka2_1:1,P00552,0.177499,NO,123,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.888,-4.152,3.264,,0.007,H,A,0.55,-0.4,1.447,,48.86,BHB,-1.301,0.520039,0.00325188,0.177499 beta-lactamase_2500_I280F,beta-lactamase_2500_280,TEM-1,beta-lactamase_2500,P62593,0.177516,NO,280,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.361275,0.0530888,0.177516 beta-lactamase_156_I258R,beta-lactamase_156_258,TEM-1,beta-lactamase_156,P62593,0.177606,NO,258,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.111618,0.007931,0.177606 beta-lactamase_2500_I258K,beta-lactamase_2500_258,TEM-1,beta-lactamase_2500,P62593,0.177697,NO,258,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.361275,0.007931,0.177697 kka2_1:1_D261F,kka2_1:1_261,Kka2,kka2_1:1,P00552,0.177793,NO,261,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.708,-4.32,3.612,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.520039,0.0224846,0.177793 kka2_1:4_D208P,kka2_1:4_208,Kka2,kka2_1:4,P00552,0.177823,NO,208,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.708,-3.683,2.975,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.168804,0.00212588,0.177823 beta-lactamase_2500_I244S,beta-lactamase_2500_244,TEM-1,beta-lactamase_2500,P62593,0.177889,NO,244,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.555,-3.602,2.047,,,E,B,0.48,-0.84,1.683,,77.62,OHH,-1.385,0.361275,0.00605379,0.177889 beta-lactamase_2500_D177A,beta-lactamase_2500_177,TEM-1,beta-lactamase_2500,P62593,0.177907,NO,177,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.967,-2.529,1.562,,0.006,T,L,0.75,-1.02,4.131,,64.69,BAP,-0.873667,0.361275,0.000864022,0.177907 beta-lactamase_39_I125P,beta-lactamase_39_125,TEM-1,beta-lactamase_39,P62593,0.177953,NO,125,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.441,-4.116,2.675,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.0495842,0.00383964,0.177953 kka2_1:4_D62N,kka2_1:4_62,Kka2,kka2_1:4,P00552,0.178045,NO,62,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.591,-2.947,1.356,,0.262,H,A,0.29,0.08,14.756,14.756,64.39,PAA,-1.77833,0.168804,0.00744243,0.178045 beta-lactamase_V258Y,beta-lactamase_258,TEM-1,beta-lactamase,P62593,0.178127,NO,258,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.975,-4.226,2.251,5.16083,,E,B,1.64,-1.02,2.124,,67.83,HHH,-1.67667,0.221079,0.007931,0.178127 beta-lactamase_2500_T178L,beta-lactamase_2500_178,TEM-1,beta-lactamase_2500,P62593,0.178184,NO,178,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-0.791,-3.133,2.342,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.361275,0.000684366,0.178184 kka2_1:4_H188T,kka2_1:4_188,Kka2,kka2_1:4,P00552,0.178187,NO,188,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-0.913,-3.673,2.76,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.168804,0.00273139,0.178187 kka2_1:1_L259Q,kka2_1:1_259,Kka2,kka2_1:1,P00552,0.178208,NO,259,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.088,-4.124,3.036,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.520039,0.0206964,0.178208 kka2_1:2_M148S,kka2_1:2_148,Kka2,kka2_1:2,P00552,0.178226,NO,148,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.847,-3.618,1.771,,0.268,H,A,1.59,0.71,1.439,,64.39,BHA,-1.65467,0.295029,0.00982664,0.178226 beta-lactamase_D177Y,beta-lactamase_177,TEM-1,beta-lactamase,P62593,0.178272,NO,177,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.967,-4.413,3.446,5.08038,0.006,T,L,1.59,-1.02,3.536,,64.69,BAP,-0.873667,0.221079,0.000864022,0.178272 beta-lactamase_L188E,beta-lactamase_188,TEM-1,beta-lactamase,P62593,0.178313,NO,188,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.166,-2.834,1.668,5.55434,,H,A,1.07,-0.3,1.574,,60.14,PHB,-1.47033,0.221079,0.00295687,0.178313 beta-lactamase_2500_M67W,beta-lactamase_2500_67,TEM-1,beta-lactamase_2500,P62593,0.178334,NO,67,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-2.231,-5.379,3.148,,0.006,G,P,0.55,-0.81,2.653,,65.03,HHP,-1.502,0.361275,0.00409753,0.178334 beta-lactamase_156_C121K,beta-lactamase_156_121,TEM-1,beta-lactamase_156,P62593,0.178457,NO,121,C,K,CK,Special,PositiveCharge,5.07,9.74,4.67,202,121,146,25,108.5,168.6,60.1,-0.953,-3.72,2.767,,,H,A,0.46,-0.81,1.136,,63.29,HOP,-1.46767,0.111618,0.000744322,0.178457 beta-lactamase_625_E35P,beta-lactamase_625_35,TEM-1,beta-lactamase_625,P62593,0.17852,NO,35,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-0.869,-3.68,2.811,,0.15,H,A,1.04,0.21,0.664,,46.85,HAA,-1.88667,0.213352,0.00174441,0.17852 kka2_1:4_G30T,kka2_1:4_30,Kka2,kka2_1:4,P00552,0.178527,NO,30,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.596,-3.675,3.079,,0.54,S,g,0.29,3.76,,,,HOO,-1.51133,0.168804,0.00159208,0.178527 E1_Ubiquitin_G75M,E1_Ubiquitin_75,Uba1,E1_Ubiquitin,P0CG63,0.178603,NO,75,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.999,-4.67,3.671,,0.552,T,A,0.75,0.9,4.369,,83.73,BOO,-1.1,0.18783,0.00153276,0.178603 E1_Ubiquitin_G75Y,E1_Ubiquitin_75,Uba1,E1_Ubiquitin,P0CG63,0.178603,NO,75,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.999,-4.198,3.199,,0.552,T,A,0.75,0.9,4.369,,83.73,BOO,-1.1,0.18783,0.00153276,0.178603 kka2_1:2_W91M,kka2_1:2_91,Kka2,kka2_1:2,P00552,0.178612,NO,91,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-1.178,-4.551,3.373,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.295029,0.00358653,0.178612 beta-lactamase_2500_R162I,beta-lactamase_2500_162,TEM-1,beta-lactamase_2500,P62593,0.178639,NO,162,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.016,-3.867,2.851,,0.124,S,B,1.2,-0.37,6.199,,64.69,ABH,-1.25,0.361275,0.000561334,0.178639 kka2_1:4_R226M,kka2_1:4_226,Kka2,kka2_1:4,P00552,0.178661,NO,226,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.392,-4.698,3.306,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.168804,0.0108032,0.178661 kka2_1:1_F256N,kka2_1:1_256,Kka2,kka2_1:1,P00552,0.17872,NO,256,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.49,-4.16,2.67,,,H,A,1.62,-0.78,2.354,,53.03,HHH,-1.423,0.520039,0.0132841,0.17872 PSD95pdz3_G324T,PSD95pdz3_324,PSD95pdz3,PSD95pdz3,P31016,0.178724,NO,324,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.008,-3.328,2.32,4.98881,,,,,10.4525,,,,HOH,-1.293,0.0758425,0.00103462,0.178724 beta-lactamase_2500_A133F,beta-lactamase_2500_133,TEM-1,beta-lactamase_2500,P62593,0.178749,NO,133,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.186,-4.224,3.038,,,H,A,0.46,-0.86,2.649,,67.83,HHP,-0.988333,0.361275,0.00468022,0.178749 kka2_1:1_H135G,kka2_1:1_135,Kka2,kka2_1:1,P00552,0.178796,NO,135,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-1.331,-3.471,2.14,,0.071,.,a,0.17,0.65,3.574,,53.03,ABP,-1.77367,0.520039,0.00532566,0.178796 kka2_1:1_Q219F,kka2_1:1_219,Kka2,kka2_1:1,P00552,0.178847,NO,219,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-0.93,-4.344,3.414,,0.088,H,A,0.4,-0.85,1.917,,50,HPA,-1.05167,0.520039,0.00237913,0.178847 beta-lactamase_2500_G43R,beta-lactamase_2500_43,TEM-1,beta-lactamase_2500,P62593,0.178899,NO,43,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.62,-3.933,3.313,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.361275,0.00120151,0.178899 beta-lactamase_625_V259P,beta-lactamase_625_259,TEM-1,beta-lactamase_625,P62593,0.178904,NO,259,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.213352,0.0070773,0.178904 kka2_1:2_D208H,kka2_1:2_208,Kka2,kka2_1:2,P00552,0.178918,NO,208,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.708,-4.483,3.775,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.295029,0.00212588,0.178918 kka2_1:4_D190H,kka2_1:4_190,Kka2,kka2_1:4,P00552,0.178967,NO,190,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.708,-4.483,3.775,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.168804,0.00247989,0.178967 kka2_1:4_G213F,kka2_1:4_213,Kka2,kka2_1:4,P00552,0.178967,NO,213,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.596,-4.32,3.724,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.168804,0.00187654,0.178967 kka2_1:2_W91A,kka2_1:2_91,Kka2,kka2_1:2,P00552,0.178998,NO,91,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-1.178,-3.5,2.322,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.295029,0.00358653,0.178998 kka2_1:2_L193S,kka2_1:2_193,Kka2,kka2_1:2,P00552,0.179062,NO,193,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.983,-3.624,2.641,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.295029,0.00480179,0.179062 kka2_1:2_S104D,kka2_1:2_104,Kka2,kka2_1:2,P00552,0.179087,NO,104,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.436,-2.848,1.412,,0.536,T,A,0.27,-1.11,5.49,,63.64,HPP,-1.91433,0.295029,0.00555207,0.179087 kka2_1:2_V186S,kka2_1:2_186,Kka2,kka2_1:2,P00552,0.17911,NO,186,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.011,-3.722,2.711,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.295029,0.00409703,0.17911 kka2_1:8_F240M,kka2_1:8_240,Kka2,kka2_1:8,P00552,0.179167,NO,240,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-0.911,-4.239,3.328,,,H,A,1.62,-1.21,0.697,,50.38,BHH,-1.67267,0.100394,0.00552543,0.179167 kka2_1:8_F240M,kka2_1:8_240,Kka2,kka2_1:8,P00552,0.179167,NO,240,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-0.911,-4.239,3.328,,,H,A,1.62,-1.21,0.697,,50.38,BHH,-1.67267,0.100394,0.00552543,0.179167 kka2_1:2_G213N,kka2_1:2_213,Kka2,kka2_1:2,P00552,0.179226,NO,213,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.596,-3.476,2.88,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.295029,0.00187654,0.179226 beta-lactamase_S233F,beta-lactamase_233,TEM-1,beta-lactamase,P62593,0.179228,NO,233,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.886,-4.226,2.34,4.98121,0.016,E,B,0.48,-1.01,5.361,,77.62,BPO,-1.17267,0.221079,0.00311415,0.179228 beta-lactamase_2500_K71I,beta-lactamase_2500_71,TEM-1,beta-lactamase_2500,P62593,0.179316,NO,71,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-0.8,-4.01,3.21,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.361275,0.00103192,0.179316 kka2_1:1_T73H,kka2_1:1_73,Kka2,kka2_1:1,P00552,0.17933,NO,73,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.51,-3.503,0.993,,0.309,H,A,0.22,0.35,4.126,,56.06,PPO,-2.02333,0.520039,0.00628605,0.17933 beta-lactamase_2500_D155I,beta-lactamase_2500_155,TEM-1,beta-lactamase_2500,P62593,0.179332,NO,155,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.889,-4.06,3.171,,0.049,,B,0.75,-0.9,2.386,,64.69,OAB,-1.62267,0.361275,0.00135315,0.179332 beta-lactamase_S240I,beta-lactamase_240,TEM-1,beta-lactamase,P62593,0.179447,NO,240,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.537,-3.83,2.293,4.75024,,,B,0.74,-0.74,0.357,,65.38,OPB,-1.263,0.221079,0.00591201,0.179447 beta-lactamase_156_A124K,beta-lactamase_156_124,TEM-1,beta-lactamase_156,P62593,0.179478,NO,124,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.181,-3.561,2.38,,,H,A,0.46,-0.9,2.027,,64.34,HHH,-1.152,0.111618,0.00481399,0.179478 kka2_1:2_A78V,kka2_1:2_78,Kka2,kka2_1:2,P00552,0.179492,NO,78,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.744,-3.452,1.708,,0.078,.,B,0.46,-0.53,0.206,,56.06,OHH,-1.863,0.295029,0.00457299,0.179492 beta-lactamase_2500_E35H,beta-lactamase_2500_35,TEM-1,beta-lactamase_2500,P62593,0.179548,NO,35,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-0.869,-4.279,3.41,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.361275,0.00174441,0.179548 kka2_1:8_T187Y,kka2_1:8_187,Kka2,kka2_1:8,P00552,0.179567,NO,187,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.273,-4.308,3.035,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.100394,0.00693073,0.179567 kka2_1:8_T187Y,kka2_1:8_187,Kka2,kka2_1:8,P00552,0.179567,NO,187,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.273,-4.308,3.035,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.100394,0.00693073,0.179567 kka2_1:1_E59R,kka2_1:1_59,Kka2,kka2_1:1,P00552,0.179584,NO,59,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-0.952,-3.602,2.65,,0.187,.,L,1.04,0.62,2.648,,50.38,PAH,-1.53,0.520039,0.00280355,0.179584 kka2_1:1_I254N,kka2_1:1_254,Kka2,kka2_1:1,P00552,0.179599,NO,254,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.933,-4.208,2.275,,0.135,H,A,1.52,-0.6,1.859,,71.59,BHH,-1.668,0.520039,0.0132375,0.179599 kka2_1:4_D261K,kka2_1:4_261,Kka2,kka2_1:4,P00552,0.179693,NO,261,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.708,-3.485,2.777,,0.146,G,A,0.75,-0.33,,,,HAA,-0.759333,0.168804,0.0224846,0.179693 beta-lactamase_156_G234I,beta-lactamase_156_234,TEM-1,beta-lactamase_156,P62593,0.179715,NO,234,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.62,-4.235,3.615,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.111618,0.000889577,0.179715 beta-lactamase_625_I45P,beta-lactamase_625_45,TEM-1,beta-lactamase_625,P62593,0.17974,NO,45,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-2.421,-4.091,1.67,,,E,B,0.48,-0.3,3.642,,77.62,HHA,-2.30267,0.213352,0.00452842,0.17974 beta-lactamase_2500_G236K,beta-lactamase_2500_236,TEM-1,beta-lactamase_2500,P62593,0.179864,NO,236,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.784,-3.651,2.867,,0.241,,b,0.29,-0.59,2.14,,64.69,HOO,-1.025,0.361275,0.00162372,0.179864 beta-lactamase_625_P65M,beta-lactamase_625_65,TEM-1,beta-lactamase_625,P62593,0.179908,NO,65,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.894,-4.494,3.6,,0.098,E,B,0.52,-0.62,0.3,,40.56,HOH,-1.03233,0.213352,0.00152776,0.179908 kka2_1:1_D118K,kka2_1:1_118,Kka2,kka2_1:1,P00552,0.179936,NO,118,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.07,-2.906,0.836,,0.61,H,A,0.75,-0.05,13.434,13.434,64.39,HAH,-1.32367,0.520039,0.0067852,0.179936 beta-lactamase_156_A230D,beta-lactamase_156_230,TEM-1,beta-lactamase_156,P62593,0.180027,NO,230,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.154,-3.645,2.491,,0.01,E,B,0.46,-1.17,2.179,,50,HHA,-1.079,0.111618,0.00516841,0.180027 kka2_1:1_T187H,kka2_1:1_187,Kka2,kka2_1:1,P00552,0.180048,NO,187,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.273,-4.848,3.575,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.520039,0.00693073,0.180048 beta-lactamase_2500_D129N,beta-lactamase_2500_129,TEM-1,beta-lactamase_2500,P62593,0.180068,NO,129,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.816,-3.272,2.456,,,,B,0.75,-0.69,1.29,,34.97,PAP,-0.818,0.361275,0.00109178,0.180068 beta-lactamase_625_G76E,beta-lactamase_625_76,TEM-1,beta-lactamase_625,P62593,0.180105,NO,76,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.189,-3.614,2.425,,,H,A,0.29,-0.67,3.059,,67.83,OOH,-1.22267,0.213352,0.00476637,0.180105 beta-lactamase_625_A230K,beta-lactamase_625_230,TEM-1,beta-lactamase_625,P62593,0.180111,NO,230,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.154,-3.583,2.429,,0.01,E,B,0.46,-1.17,0.777,,50,HHA,-1.079,0.213352,0.00516841,0.180111 kka2_1:2_L260K,kka2_1:2_260,Kka2,kka2_1:2,P00552,0.18013,NO,260,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.741,-3.71,2.969,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.295029,0.0233782,0.18013 beta-lactamase_2500_A132D,beta-lactamase_2500_132,TEM-1,beta-lactamase_2500,P62593,0.180146,NO,132,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.9,-3.706,2.806,,,H,A,0.46,-0.93,8.408,,64.69,PHH,-1.138,0.361275,0.000962524,0.180146 beta-lactamase_625_T107F,beta-lactamase_625_107,TEM-1,beta-lactamase_625,P62593,0.180194,NO,107,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.117,-4.119,3.002,,,G,A,0.22,-0.06,3.676,,67.83,HPA,-1.265,0.213352,0.00239347,0.180194 beta-lactamase_2500_T131K,beta-lactamase_2500_131,TEM-1,beta-lactamase_2500,P62593,0.180216,NO,131,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.328,-3.481,2.153,,,H,A,0.22,-0.69,3.048,,67.48,PPH,-1.00867,0.361275,0.00345886,0.180216 kka2_1:1_D190I,kka2_1:1_190,Kka2,kka2_1:1,P00552,0.180224,NO,190,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.708,-4.039,3.331,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.520039,0.00247989,0.180224 beta-lactamase_156_L167K,beta-lactamase_156_167,TEM-1,beta-lactamase_156,P62593,0.180244,NO,167,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.138,-3.594,2.456,,0.015,G,A,0.55,-0.63,0.4,,64.69,AHP,-1.30767,0.111618,0.00303566,0.180244 kka2_1:2_T187W,kka2_1:2_187,Kka2,kka2_1:2,P00552,0.180356,NO,187,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.273,-5.339,4.066,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.295029,0.00693073,0.180356 E1_Ubiquitin_H70D,E1_Ubiquitin_70,Uba1,E1_Ubiquitin,P0CG63,0.180371,NO,70,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-1.36,,,,0.05,E,B,0.61,-0.97,,,93.18,HBH,-1.146,0.18783,0.00206914,0.180371 beta-lactamase_2500_R59F,beta-lactamase_2500_59,TEM-1,beta-lactamase_2500,P62593,0.180374,NO,59,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.345,-4.379,3.034,,0.329,S,L,1.2,-0.09,3.719,,73.08,HBO,-2.24267,0.361275,0.00318082,0.180374 beta-lactamase_2500_L136S,beta-lactamase_2500_136,TEM-1,beta-lactamase_2500,P62593,0.180398,NO,136,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.232,-3.705,2.473,,,H,A,0.55,-0.34,1.36,,48.95,HHH,-1.088,0.361275,0.00442304,0.180398 kka2_1:2_D208P,kka2_1:2_208,Kka2,kka2_1:2,P00552,0.180407,NO,208,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.708,-3.683,2.975,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.295029,0.00212588,0.180407 kka2_1:4_V80D,kka2_1:4_80,Kka2,kka2_1:4,P00552,0.180428,NO,80,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.144,-3.971,2.827,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.168804,0.00488211,0.180428 hsp90_A587I,hsp90_587,hsp90,hsp90,P02829,0.180449,NO,587,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.456,-2.939,0,4.91216,0.049,H,A,0.55,-0.02,,,,PHP,-2.757,0.368192,0.000222939,0.180449 kka2_1:1_G10H,kka2_1:1_10,Kka2,kka2_1:1,P00552,0.18045,NO,10,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.921,-4.434,2.513,,,,,,,1.862,,71.59,HOP,-2.10733,0.520039,0.00289233,0.18045 beta-lactamase_625_G243D,beta-lactamase_625_243,TEM-1,beta-lactamase_625,P62593,0.180459,NO,243,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.213352,0.00464034,0.180459 kka2_1:1_V185F,kka2_1:1_185,Kka2,kka2_1:1,P00552,0.180481,NO,185,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.045,-3.962,2.917,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.520039,0.00367031,0.180481 beta-lactamase_2500_L136D,beta-lactamase_2500_136,TEM-1,beta-lactamase_2500,P62593,0.180549,NO,136,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.232,-4.137,2.905,,,H,A,0.55,-0.34,1.36,,48.95,HHH,-1.088,0.361275,0.00442304,0.180549 kka2_1:8_D216I,kka2_1:8_216,Kka2,kka2_1:8,P00552,0.180565,NO,216,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.785,-4.062,3.277,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.100394,0.00229969,0.180565 kka2_1:8_D216I,kka2_1:8_216,Kka2,kka2_1:8,P00552,0.180565,NO,216,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.785,-4.062,3.277,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.100394,0.00229969,0.180565 kka2_1:1_G88I,kka2_1:1_88,Kka2,kka2_1:1,P00552,0.180598,NO,88,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.689,-4.119,2.43,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.520039,0.00685559,0.180598 beta-lactamase_Y260H,beta-lactamase_260,TEM-1,beta-lactamase,P62593,0.180616,NO,260,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-1.101,-4.045,2.944,5.50878,,E,B,0.73,-1.04,0.865,,60.49,HHP,-1.83433,0.221079,0.00471757,0.180616 beta-lactamase_39_W227K,beta-lactamase_39_227,TEM-1,beta-lactamase_39,P62593,0.180619,NO,227,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-0.982,-3.931,2.949,,0.272,,B,0.47,-0.29,1.37,,74.48,OHH,-1.595,0.0495842,0.00226019,0.180619 beta-lactamase_2500_I280E,beta-lactamase_2500_280,TEM-1,beta-lactamase_2500,P62593,0.180633,NO,280,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.361275,0.0530888,0.180633 kka2_1:1_N200I,kka2_1:1_200,Kka2,kka2_1:1,P00552,0.180634,NO,200,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-2.446,-4.261,1.815,,0.756,T,L,0.61,-0.08,17.299,17.299,64.39,APO,-2.08,0.520039,0.00838549,0.180634 kka2_1:1_R217T,kka2_1:1_217,Kka2,kka2_1:1,P00552,0.180658,NO,217,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.158,-3.559,2.401,,0.252,T,A,1.2,-0.59,0.381,,52.27,ABH,-1.127,0.520039,0.0047191,0.180658 beta-lactamase_625_W227H,beta-lactamase_625_227,TEM-1,beta-lactamase_625,P62593,0.180671,NO,227,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-0.982,-4.704,3.722,,0.272,,B,0.47,-0.29,2.533,,74.48,OHH,-1.595,0.213352,0.00226019,0.180671 beta-lactamase_625_I93D,beta-lactamase_625_93,TEM-1,beta-lactamase_625,P62593,0.18071,NO,93,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.401,-4.003,2.602,,0.128,E,B,0.48,0.44,1.524,,67.83,BHB,-1.873,0.213352,0.00527066,0.18071 kka2_1:2_F48A,kka2_1:2_48,Kka2,kka2_1:2,P00552,0.180714,NO,48,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.453,-3.34,1.887,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.295029,0.00475422,0.180714 beta-lactamase_156_A124H,beta-lactamase_156_124,TEM-1,beta-lactamase_156,P62593,0.180788,NO,124,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.181,-4.785,3.604,,,H,A,0.46,-0.9,2.027,,64.34,HHH,-1.152,0.111618,0.00481399,0.180788 beta-lactamase_156_I245W,beta-lactamase_156_245,TEM-1,beta-lactamase_156,P62593,0.180795,NO,245,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.111618,0.00391032,0.180795 beta-lactamase_2500_K232A,beta-lactamase_2500_232,TEM-1,beta-lactamase_2500,P62593,0.180801,NO,232,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.012,-3.12,2.108,,,E,B,2.34,-1.1,3.048,,65.03,ABP,-1.238,0.361275,0.00313441,0.180801 kka2_1:4_R226Q,kka2_1:4_226,Kka2,kka2_1:4,P00552,0.180864,NO,226,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.392,-2.994,1.602,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.168804,0.0108032,0.180864 kka2_1:2_D220L,kka2_1:2_220,Kka2,kka2_1:2,P00552,0.180895,NO,220,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.787,-3.669,2.882,,,H,A,0.75,-1.14,0.745,,46.59,PAH,-1.152,0.295029,0.00158066,0.180895 beta-lactamase_625_L192E,beta-lactamase_625_192,TEM-1,beta-lactamase_625,P62593,0.180975,NO,192,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.254,-3.893,2.639,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.213352,0.00558728,0.180975 beta-lactamase_625_S201E,beta-lactamase_625_201,TEM-1,beta-lactamase_625,P62593,0.180982,NO,201,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.183,-3.352,2.169,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.213352,0.00198815,0.180982 kka2_1:4_D227W,kka2_1:4_227,Kka2,kka2_1:4,P00552,0.181015,NO,227,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.758,-5.454,3.696,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.168804,0.00745029,0.181015 beta-lactamase_156_S128F,beta-lactamase_156_128,TEM-1,beta-lactamase_156,P62593,0.181035,NO,128,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-0.84,-4.067,3.227,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.111618,0.00071483,0.181035 kka2_1:1_N58C,kka2_1:1_58,Kka2,kka2_1:1,P00552,0.181061,NO,58,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-2.641,-2.921,0.28,,0.131,S,A,0.61,0.72,30.755,30.755,71.59,HPA,-1.83033,0.520039,0.00793425,0.181061 kka2_1:1_P194F,kka2_1:1_194,Kka2,kka2_1:1,P00552,0.18109,NO,194,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.846,-4.517,3.671,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.520039,0.00314194,0.18109 PSD95pdz3_G329H,PSD95pdz3_329,PSD95pdz3,PSD95pdz3,P31016,0.181092,NO,329,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.008,-4.362,3.354,4.7671,,,,,19.7075,,,,HOO,-1.16033,0.0758425,0.000974577,0.181092 kka2_1:1_F206Y,kka2_1:1_206,Kka2,kka2_1:1,P00552,0.181096,NO,206,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.349,-1.759,0.41,,0.006,E,B,0.58,-1.21,0.978,,63.64,OHH,-1.04,0.520039,0.00936868,0.181096 kka2_1:2_A144D,kka2_1:2_144,Kka2,kka2_1:2,P00552,0.181154,NO,144,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.859,-3.804,2.945,,,H,A,0.46,0.21,6.844,,52.65,BHB,-1.72933,0.295029,0.00231095,0.181154 kka2_1:8_G30L,kka2_1:8_30,Kka2,kka2_1:8,P00552,0.181163,NO,30,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.596,-3.836,3.24,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.100394,0.00159208,0.181163 kka2_1:8_G30L,kka2_1:8_30,Kka2,kka2_1:8,P00552,0.181163,NO,30,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.596,-3.836,3.24,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.100394,0.00159208,0.181163 beta-lactamase_625_K71R,beta-lactamase_625_71,TEM-1,beta-lactamase_625,P62593,0.181251,NO,71,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-0.8,-3.033,2.233,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.213352,0.00103192,0.181251 beta-lactamase_156_I277D,beta-lactamase_156_277,TEM-1,beta-lactamase_156,P62593,0.181325,NO,277,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.111618,0.0169305,0.181325 kka2_1:8_L260E,kka2_1:8_260,Kka2,kka2_1:8,P00552,0.181362,NO,260,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.741,-3.918,3.177,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.100394,0.0233782,0.181362 kka2_1:8_L260E,kka2_1:8_260,Kka2,kka2_1:8,P00552,0.181362,NO,260,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.741,-3.918,3.177,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.100394,0.0233782,0.181362 kka2_1:8_L94G,kka2_1:8_94,Kka2,kka2_1:8,P00552,0.181362,NO,94,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.618,-3.801,2.183,,0.058,E,B,1.59,-0.52,2.197,,56.06,HHO,-1.612,0.100394,0.00520888,0.181362 kka2_1:8_L94G,kka2_1:8_94,Kka2,kka2_1:8,P00552,0.181362,NO,94,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.618,-3.801,2.183,,0.058,E,B,1.59,-0.52,2.197,,56.06,HHO,-1.612,0.100394,0.00520888,0.181362 beta-lactamase_156_K232H,beta-lactamase_156_232,TEM-1,beta-lactamase_156,P62593,0.181366,NO,232,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.012,-4.433,3.421,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.111618,0.00313441,0.181366 beta-lactamase_L282D,beta-lactamase_282,TEM-1,beta-lactamase,P62593,0.181434,NO,282,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.586,-4.066,2.48,5.16743,0.007,H,A,1.07,0.34,31.31,31.31,63.99,PHH,-1.82367,0.221079,0.0449821,0.181434 beta-lactamase_2500_G52C,beta-lactamase_2500_52,TEM-1,beta-lactamase_2500,P62593,0.181443,NO,52,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.149,-5.084,3.935,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.361275,0.00340138,0.181443 beta-lactamase_156_I261P,beta-lactamase_156_261,TEM-1,beta-lactamase_156,P62593,0.181576,NO,261,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.111618,0.0123091,0.181576 beta-lactamase_2500_L137N,beta-lactamase_2500_137,TEM-1,beta-lactamase_2500,P62593,0.181639,NO,137,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.03,-4.152,3.122,,,H,A,0.55,-0.38,0.769,,42.31,HHP,-1.58933,0.361275,0.00278599,0.181639 PSD95pdz3_I338R,PSD95pdz3_338,PSD95pdz3,PSD95pdz3,P31016,0.181777,NO,338,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.63,-3.84,2.21,5.45113,,,,,13.0087,,,,HHP,-1.55767,0.0758425,0.000862587,0.181777 beta-lactamase_2500_G236M,beta-lactamase_2500_236,TEM-1,beta-lactamase_2500,P62593,0.181782,NO,236,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.784,-4.869,4.085,,0.241,,b,0.29,-0.59,2.14,,64.69,HOO,-1.025,0.361275,0.00162372,0.181782 beta-lactamase_39_T69Y,beta-lactamase_39_69,TEM-1,beta-lactamase_39,P62593,0.181795,NO,69,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-0.973,-4.223,3.25,,,G,A,0.22,-1.24,4.194,,93.01,PPH,-1.01833,0.0495842,0.00127498,0.181795 beta-lactamase_39_R242P,beta-lactamase_39_242,TEM-1,beta-lactamase_39,P62593,0.1818,NO,242,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.0495842,0.00452879,0.1818 beta-lactamase_2500_A40K,beta-lactamase_2500_40,TEM-1,beta-lactamase_2500,P62593,0.181813,NO,40,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.402,-3.658,2.256,,0.155,S,B,0.46,0.21,0.953,,73.78,OHB,-1.40267,0.361275,0.00490026,0.181813 beta-lactamase_2500_S201E,beta-lactamase_2500_201,TEM-1,beta-lactamase_2500,P62593,0.181821,NO,201,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.183,-3.352,2.169,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.361275,0.00198815,0.181821 PSD95pdz3_L353E,PSD95pdz3_353,PSD95pdz3,PSD95pdz3,P31016,0.18184,NO,353,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.347,-3.572,2.225,5.81136,,,,,17.3525,,,,AHB,-1.50533,0.0758425,0.000664742,0.18184 kka2_1:2_V113G,kka2_1:2_113,Kka2,kka2_1:2,P00552,0.181908,NO,113,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.233,-3.759,2.526,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.295029,0.00650191,0.181908 kka2_1:8_V75G,kka2_1:8_75,Kka2,kka2_1:8,P00552,0.181958,NO,75,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-2.06,-3.863,1.803,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.100394,0.00693733,0.181958 kka2_1:8_V75G,kka2_1:8_75,Kka2,kka2_1:8,P00552,0.181958,NO,75,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-2.06,-3.863,1.803,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.100394,0.00693733,0.181958 beta-lactamase_2500_L205N,beta-lactamase_2500_205,TEM-1,beta-lactamase_2500,P62593,0.181959,NO,205,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.922,-4.141,3.219,,,H,A,0.55,-0.46,0.831,,42.31,PHH,-1.57767,0.361275,0.00255802,0.181959 kka2_1:1_T225Q,kka2_1:1_225,Kka2,kka2_1:1,P00552,0.181973,NO,225,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.393,-3.262,0.869,,0.036,H,A,0.22,-1.22,4.554,,63.64,HPB,-1.58733,0.520039,0.0113598,0.181973 kka2_1:1_G95P,kka2_1:1_95,Kka2,kka2_1:1,P00552,0.181997,NO,95,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-2.403,-3.948,1.545,,0.126,E,B,0.29,-0.74,7.822,,71.59,HOA,-2.198,0.520039,0.00743616,0.181997 beta-lactamase_625_T27W,beta-lactamase_625_27,TEM-1,beta-lactamase_625,P62593,0.182011,NO,27,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.905,-5.314,3.409,,0.007,H,A,0.22,-0.37,3.72,,93.01,APH,-1.97933,0.213352,0.00306559,0.182011 kka2_1:1_L243I,kka2_1:1_243,Kka2,kka2_1:1,P00552,0.182012,NO,243,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-2.651,-3.227,0.576,,0.277,H,A,0.55,-0.67,4.334,,92.05,HHH,-2.03767,0.520039,0.00884927,0.182012 beta-lactamase_2500_C121Q,beta-lactamase_2500_121,TEM-1,beta-lactamase_2500,P62593,0.182022,NO,121,C,Q,CQ,Special,Polar,5.07,6.24429,1.17429,154,121,146,25,108.5,143.8,35.3,-0.953,-4.222,3.269,,,H,A,0.46,-0.81,1.174,,63.29,HOP,-1.46767,0.361275,0.000744322,0.182022 kka2_1:1_L126W,kka2_1:1_126,Kka2,kka2_1:1,P00552,0.182022,NO,126,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.246,-5.346,4.1,,0.285,S,B,0.55,0.12,0.302,,51.89,PHA,-1.744,0.520039,0.0066485,0.182022 beta-lactamase_2500_R162F,beta-lactamase_2500_162,TEM-1,beta-lactamase_2500,P62593,0.182132,NO,162,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.016,-4.266,3.25,,0.124,S,B,1.2,-0.37,6.199,,64.69,ABH,-1.25,0.361275,0.000561334,0.182132 kka2_1:1_G245W,kka2_1:1_245,Kka2,kka2_1:1,P00552,0.182186,NO,245,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.812,-5.257,4.445,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.520039,0.00683899,0.182186 kka2_1:1_R258F,kka2_1:1_258,Kka2,kka2_1:1,P00552,0.182208,NO,258,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.626,-4.327,2.701,,0.316,H,A,1.2,-0.85,7.485,7.485,53.03,HBH,-1.25933,0.520039,0.00983174,0.182208 kka2_1:1_Q219G,kka2_1:1_219,Kka2,kka2_1:1,P00552,0.182316,NO,219,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-0.93,-3.41,2.48,,0.088,H,A,0.4,-0.85,1.917,,50,HPA,-1.05167,0.520039,0.00237913,0.182316 beta-lactamase_625_F64D,beta-lactamase_625_64,TEM-1,beta-lactamase_625,P62593,0.182346,NO,64,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-0.841,-3.919,3.078,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.213352,0.000947691,0.182346 kka2_1:1_M178D,kka2_1:1_178,Kka2,kka2_1:1,P00552,0.182409,NO,178,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-3.206,-3.894,0.688,,0.554,.,b,0.55,0.68,3.152,,71.59,BHO,-2.154,0.520039,0.00717253,0.182409 kka2_1:2_F206Q,kka2_1:2_206,Kka2,kka2_1:2,P00552,0.182566,NO,206,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.349,-4.252,2.903,,0.006,E,B,0.58,-1.21,0.978,,63.64,OHH,-1.04,0.295029,0.00936868,0.182566 kka2_1:1_R89N,kka2_1:1_89,Kka2,kka2_1:1,P00552,0.182587,NO,89,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.548,-3.002,1.454,,0.209,E,B,0.16,1.41,14.396,14.396,64.39,OBA,-1.89867,0.520039,0.00524373,0.182587 beta-lactamase_39_L137P,beta-lactamase_39_137,TEM-1,beta-lactamase_39,P62593,0.182622,NO,137,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.03,-4.134,3.104,,,H,A,0.55,-0.38,0.674,,42.31,HHP,-1.58933,0.0495842,0.00278599,0.182622 kka2_1:1_G213T,kka2_1:1_213,Kka2,kka2_1:1,P00552,0.18268,NO,213,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.596,-3.675,3.079,,,E,b,0.29,-0.4,,,,HOH,-0.920333,0.520039,0.00187654,0.18268 kka2_1:2_G201W,kka2_1:2_201,Kka2,kka2_1:2,P00552,0.182698,NO,201,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.56,-5.537,3.977,,0.149,T,l,0.29,-0.57,16.092,16.092,52.65,POB,-1.92233,0.295029,0.00820117,0.182698 beta-lactamase_625_L167R,beta-lactamase_625_167,TEM-1,beta-lactamase_625,P62593,0.18279,NO,167,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.138,-2.876,1.738,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.213352,0.00303566,0.18279 beta-lactamase_156_A132H,beta-lactamase_156_132,TEM-1,beta-lactamase_156,P62593,0.182863,NO,132,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.9,-4.724,3.824,,,H,A,0.46,-0.93,10.621,,64.69,PHH,-1.138,0.111618,0.000962524,0.182863 beta-lactamase_625_G243F,beta-lactamase_625_243,TEM-1,beta-lactamase_625,P62593,0.182889,NO,243,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.213352,0.00464034,0.182889 kka2_1:4_L19N,kka2_1:4_19,Kka2,kka2_1:4,P00552,0.182961,NO,19,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.254,-4.186,2.932,,0.08,T,A,1.59,-0.26,2.645,,65.53,BHH,-2.221,0.168804,0.00620703,0.182961 beta-lactamase_2500_A132M,beta-lactamase_2500_132,TEM-1,beta-lactamase_2500,P62593,0.18306,NO,132,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.9,-4.473,3.573,,,H,A,0.46,-0.93,8.408,,64.69,PHH,-1.138,0.361275,0.000962524,0.18306 beta-lactamase_625_V117W,beta-lactamase_625_117,TEM-1,beta-lactamase_625,P62593,0.183088,NO,117,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.53,-5.228,3.698,,,H,A,0.44,-0.34,1.23,,65.03,PHB,-1.741,0.213352,0.00467906,0.183088 kka2_1:4_W236N,kka2_1:4_236,Kka2,kka2_1:4,P00552,0.183091,NO,236,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-1.363,-4.289,2.926,,0.303,H,A,0.47,-0.76,2.277,,48.48,AHH,-1.81267,0.168804,0.0088796,0.183091 kka2_1:1_D261C,kka2_1:1_261,Kka2,kka2_1:1,P00552,0.183107,NO,261,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.708,-5.115,4.407,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.520039,0.0224846,0.183107 beta-lactamase_625_W227K,beta-lactamase_625_227,TEM-1,beta-lactamase_625,P62593,0.18312,NO,227,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-0.982,-3.931,2.949,,0.272,,B,0.47,-0.29,2.533,,74.48,OHH,-1.595,0.213352,0.00226019,0.18312 beta-lactamase_2500_T69A,beta-lactamase_2500_69,TEM-1,beta-lactamase_2500,P62593,0.183242,NO,69,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-0.973,-2.115,1.142,,,G,A,0.22,-1.24,2.05,,93.01,PPH,-1.01833,0.361275,0.00127498,0.183242 kka2_1:4_V36Y,kka2_1:4_36,Kka2,kka2_1:4,P00552,0.183268,NO,36,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-0.898,-4.01,3.112,,0.292,E,B,0.44,0.21,0.278,,52.27,HHH,-1.484,0.168804,0.00245633,0.183268 beta-lactamase_2500_I125F,beta-lactamase_2500_125,TEM-1,beta-lactamase_2500,P62593,0.183292,NO,125,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.441,-3.841,2.4,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.361275,0.00383964,0.183292 beta-lactamase_156_L137P,beta-lactamase_156_137,TEM-1,beta-lactamase_156,P62593,0.183294,NO,137,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.03,-4.134,3.104,,,H,A,0.55,-0.38,0.674,,42.31,HHP,-1.58933,0.111618,0.00278599,0.183294 kka2_1:1_T73K,kka2_1:1_73,Kka2,kka2_1:1,P00552,0.183304,NO,73,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.51,-2.995,0.485,,0.309,H,A,0.22,0.35,4.126,,56.06,PPO,-2.02333,0.520039,0.00628605,0.183304 kka2_1:8_R211T,kka2_1:8_211,Kka2,kka2_1:8,P00552,0.183344,NO,211,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-0.899,-3.493,2.594,,0.12,T,a,0.16,-0.39,0.615,,49.62,OBH,-0.966,0.100394,0.00204888,0.183344 kka2_1:8_R211T,kka2_1:8_211,Kka2,kka2_1:8,P00552,0.183344,NO,211,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-0.899,-3.493,2.594,,0.12,T,a,0.16,-0.39,0.615,,49.62,OBH,-0.966,0.100394,0.00204888,0.183344 kka2_1:4_A237W,kka2_1:4_237,Kka2,kka2_1:4,P00552,0.183367,NO,237,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.12,-5.457,3.337,,0.068,H,A,0.46,-0.71,2.444,,92.05,HHA,-2.10433,0.168804,0.012257,0.183367 kka2_1:2_R258W,kka2_1:2_258,Kka2,kka2_1:2,P00552,0.18347,NO,258,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.626,-5.364,3.738,,0.316,H,A,1.2,-0.85,7.485,7.485,53.03,HBH,-1.25933,0.295029,0.00983174,0.18347 kka2_1:2_D208C,kka2_1:2_208,Kka2,kka2_1:2,P00552,0.183485,NO,208,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.708,-5.115,4.407,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.295029,0.00212588,0.183485 hsp90_F583P,hsp90_583,hsp90,hsp90,P02829,0.183585,NO,583,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-3.22,-3.033,0,5.28185,1.112,S,l,1.1,0.87,,,,PHO,-3.003,0.368192,0.000222939,0.183585 kka2_1:2_A237M,kka2_1:2_237,Kka2,kka2_1:2,P00552,0.183622,NO,237,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.12,-4.281,2.161,,0.068,H,A,0.46,-0.71,2.369,,92.05,HHA,-2.10433,0.295029,0.012257,0.183622 beta-lactamase_2500_I229G,beta-lactamase_2500_229,TEM-1,beta-lactamase_2500,P62593,0.183665,NO,229,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.267,-3.782,2.515,,0.083,E,B,0.48,-0.76,3.875,,50,HHH,-1.58767,0.361275,0.00477249,0.183665 kka2_1:1_L39H,kka2_1:1_39,Kka2,kka2_1:1,P00552,0.183734,NO,39,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.223,-4.999,3.776,,,E,B,0.55,-1.21,0.925,,71.59,BHP,-1.69167,0.520039,0.00493618,0.183734 beta-lactamase_2500_P143Y,beta-lactamase_2500_143,TEM-1,beta-lactamase_2500,P62593,0.183737,NO,143,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.967,-4.337,3.37,,0.075,H,A,0.52,-0.37,0.479,,66.78,OOB,-1.354,0.361275,0.00114551,0.183737 WW_domain_H192R,WW_domain_192,Yap65,WW_domain,P46937,0.183774,NO,192,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-1.739,-2.408,0.669,5.20314,,,,,,1.458,,78.57,PBH,-1.75033,0.153962,0.00436368,0.183774 beta-lactamase_625_T69R,beta-lactamase_625_69,TEM-1,beta-lactamase_625,P62593,0.183804,NO,69,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-0.973,-3.768,2.795,,,G,A,0.22,-1.24,2.716,,93.01,PPH,-1.01833,0.213352,0.00127498,0.183804 beta-lactamase_2500_T126F,beta-lactamase_2500_126,TEM-1,beta-lactamase_2500,P62593,0.183825,NO,126,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.122,-4.199,3.077,,0.05,H,A,0.22,-0.05,0.817,,44.41,HPH,-1.60467,0.361275,0.00244552,0.183825 PSD95pdz3_F337P,PSD95pdz3_337,PSD95pdz3,PSD95pdz3,P31016,0.183834,NO,337,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.524,-4.011,2.487,5.22838,,,,,13.4936,,,,HHH,-1.59467,0.0758425,0.000875287,0.183834 beta-lactamase_39_P181K,beta-lactamase_39_181,TEM-1,beta-lactamase_39,P62593,0.183864,NO,181,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.813,-3.483,2.67,,,H,A,0.52,-1.14,1.946,,61.54,HOH,-1.795,0.0495842,0.000703122,0.183864 beta-lactamase_T158H,beta-lactamase_158,TEM-1,beta-lactamase,P62593,0.183881,NO,158,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.116,-4.689,3.573,5.32011,0.036,,B,0.98,-0.85,2.755,,69.58,HPB,-1.269,0.221079,0.00341825,0.183881 kka2_1:2_P109H,kka2_1:2_109,Kka2,kka2_1:2,P00552,0.183896,NO,109,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.412,-3.364,1.952,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.295029,0.0070929,0.183896 Pab1_F168D,Pab1_168,Pab1,Pab1,P04147,0.183918,NO,168,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.269,-3.789,2.52,,,,,,,0.789,,56.33,OHO,-1.10033,0.175299,0.00064061,0.183918 Pab1_I152H,Pab1_152,Pab1,Pab1,P04147,0.183918,NO,152,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.345,-4.798,3.453,,0.165,E,B,1.23,-0.71,1.288,,71.4,AHH,-1.59433,0.175299,0.000740963,0.183918 kka2_1:8_P194Y,kka2_1:8_194,Kka2,kka2_1:8,P00552,0.183937,NO,194,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.846,-4.438,3.592,,0.308,G,A,0.52,-1.19,4.861,,53.03,HOP,-0.888333,0.100394,0.00314194,0.183937 kka2_1:8_P194Y,kka2_1:8_194,Kka2,kka2_1:8,P00552,0.183937,NO,194,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.846,-4.438,3.592,,0.308,G,A,0.52,-1.19,4.861,,53.03,HOP,-0.888333,0.100394,0.00314194,0.183937 kka2_1:1_L259H,kka2_1:1_259,Kka2,kka2_1:1,P00552,0.183948,NO,259,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.088,-4.939,3.851,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.520039,0.0206964,0.183948 beta-lactamase_156_A246P,beta-lactamase_156_246,TEM-1,beta-lactamase_156,P62593,0.184037,NO,246,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.121,-4.126,2.005,,0.01,E,B,0.46,-1.01,1.959,,73.78,HHH,-1.55633,0.111618,0.00569458,0.184037 beta-lactamase_156_T107W,beta-lactamase_156_107,TEM-1,beta-lactamase_156,P62593,0.184052,NO,107,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.117,-5.223,4.106,,,G,A,0.22,-0.06,0.341,,67.83,HPA,-1.265,0.111618,0.00239347,0.184052 beta-lactamase_39_V260R,beta-lactamase_39_260,TEM-1,beta-lactamase_39,P62593,0.184172,NO,260,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.0495842,0.00471757,0.184172 beta-lactamase_39_Y44D,beta-lactamase_39_44,TEM-1,beta-lactamase_39,P62593,0.184249,NO,44,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-2.547,-4.061,1.514,,,E,B,0.21,-0.45,2.683,,73.78,OHH,-1.86267,0.0495842,0.00426364,0.184249 beta-lactamase_156_I261Q,beta-lactamase_156_261,TEM-1,beta-lactamase_156,P62593,0.184263,NO,261,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.111618,0.0123091,0.184263 kka2_1:4_D261I,kka2_1:4_261,Kka2,kka2_1:4,P00552,0.184267,NO,261,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.708,-4.039,3.331,,0.146,G,A,0.75,-0.33,,,,HAA,-0.759333,0.168804,0.0224846,0.184267 kka2_1:8_V214D,kka2_1:8_214,Kka2,kka2_1:8,P00552,0.184331,NO,214,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.261,-4.099,2.838,,0.117,E,B,1.48,-0.31,1.859,,64.39,OHH,-0.941667,0.100394,0.00692782,0.184331 kka2_1:8_V214D,kka2_1:8_214,Kka2,kka2_1:8,P00552,0.184331,NO,214,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.261,-4.099,2.838,,0.117,E,B,1.48,-0.31,1.859,,64.39,OHH,-0.941667,0.100394,0.00692782,0.184331 beta-lactamase_156_M209P,beta-lactamase_156_209,TEM-1,beta-lactamase_156,P62593,0.184357,NO,209,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.442,-4.077,2.635,,,H,A,0.55,-0.97,1.066,,64.69,HHA,-1.52633,0.111618,0.00625021,0.184357 beta-lactamase_2500_M67P,beta-lactamase_2500_67,TEM-1,beta-lactamase_2500,P62593,0.184421,NO,67,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-2.231,-4.072,1.841,,0.006,G,P,0.55,-0.81,2.653,,65.03,HHP,-1.502,0.361275,0.00409753,0.184421 kka2_1:1_T187M,kka2_1:1_187,Kka2,kka2_1:1,P00552,0.18443,NO,187,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.273,-4.606,3.333,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.520039,0.00693073,0.18443 kka2_1:2_D227F,kka2_1:2_227,Kka2,kka2_1:2,P00552,0.184432,NO,227,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.758,-4.199,2.441,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.295029,0.00745029,0.184432 beta-lactamase_39_A132Q,beta-lactamase_39_132,TEM-1,beta-lactamase_39,P62593,0.184456,NO,132,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.9,-3.943,3.043,,,H,A,0.46,-0.93,8.408,,64.69,PHH,-1.138,0.0495842,0.000962524,0.184456 beta-lactamase_2500_I277K,beta-lactamase_2500_277,TEM-1,beta-lactamase_2500,P62593,0.184543,NO,277,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.361275,0.0169305,0.184543 kka2_1:4_D82T,kka2_1:4_82,Kka2,kka2_1:4,P00552,0.184627,NO,82,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.946,-3.007,1.061,,0.341,E,b,0.75,0.52,11.923,11.923,63.64,HAH,-1.98,0.168804,0.00637516,0.184627 beta-lactamase_2500_D161I,beta-lactamase_2500_161,TEM-1,beta-lactamase_2500,P62593,0.184678,NO,161,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.891,-4.034,3.143,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.361275,0.000897697,0.184678 beta-lactamase_2500_S241P,beta-lactamase_2500_241,TEM-1,beta-lactamase_2500,P62593,0.184696,NO,241,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.361275,0.00452736,0.184696 beta-lactamase_G239W,beta-lactamase_239,TEM-1,beta-lactamase,P62593,0.184704,NO,239,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.819,-5.193,4.374,4.85529,0.115,T,l,0.77,-0.62,1.817,,42.31,BOP,-1.45267,0.221079,0.00213852,0.184704 kka2_1:8_L260W,kka2_1:8_260,Kka2,kka2_1:8,P00552,0.184725,NO,260,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.741,-5.126,4.385,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.100394,0.0233782,0.184725 kka2_1:8_L260W,kka2_1:8_260,Kka2,kka2_1:8,P00552,0.184725,NO,260,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.741,-5.126,4.385,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.100394,0.0233782,0.184725 kka2_1:2_G210K,kka2_1:2_210,Kka2,kka2_1:2,P00552,0.184735,NO,210,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.095,-3.696,2.601,,0.103,T,A,0.29,-0.62,0.271,,50,OOB,-0.966667,0.295029,0.00598378,0.184735 beta-lactamase_156_I277N,beta-lactamase_156_277,TEM-1,beta-lactamase_156,P62593,0.184893,NO,277,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.111618,0.0169305,0.184893 beta-lactamase_2500_I125H,beta-lactamase_2500_125,TEM-1,beta-lactamase_2500,P62593,0.184903,NO,125,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.441,-4.965,3.524,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.361275,0.00383964,0.184903 beta-lactamase_2500_S128M,beta-lactamase_2500_128,TEM-1,beta-lactamase_2500,P62593,0.184909,NO,128,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-0.84,-4.48,3.64,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.361275,0.00071483,0.184909 kka2_1:1_A56M,kka2_1:1_56,Kka2,kka2_1:1,P00552,0.18501,NO,56,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.083,-4.776,2.693,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.520039,0.00717715,0.18501 beta-lactamase_2500_L136C,beta-lactamase_2500_136,TEM-1,beta-lactamase_2500,P62593,0.185035,NO,136,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.232,-4.751,3.519,,,H,A,0.55,-0.34,1.36,,48.95,HHH,-1.088,0.361275,0.00442304,0.185035 kka2_1:2_L126W,kka2_1:2_126,Kka2,kka2_1:2,P00552,0.185064,NO,126,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.246,-5.346,4.1,,0.285,S,B,0.55,0.12,1.392,,51.89,PHA,-1.744,0.295029,0.0066485,0.185064 beta-lactamase_2500_V78N,beta-lactamase_2500_78,TEM-1,beta-lactamase_2500,P62593,0.185076,NO,78,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.459,-4.189,2.73,,,H,A,0.44,-0.47,31.376,31.376,63.64,HHH,-1.17833,0.361275,0.00492501,0.185076 kka2_1:8_G205I,kka2_1:8_205,Kka2,kka2_1:8,P00552,0.185118,NO,205,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.596,-4.264,3.668,,,E,b,0.75,-1.05,,,,POH,-1.09933,0.100394,0.00221855,0.185118 kka2_1:8_G205I,kka2_1:8_205,Kka2,kka2_1:8,P00552,0.185118,NO,205,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.596,-4.264,3.668,,,E,b,0.75,-1.05,,,,POH,-1.09933,0.100394,0.00221855,0.185118 beta-lactamase_2500_K232W,beta-lactamase_2500_232,TEM-1,beta-lactamase_2500,P62593,0.185132,NO,232,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.012,-5.365,4.353,,,E,B,2.34,-1.1,3.048,,65.03,ABP,-1.238,0.361275,0.00313441,0.185132 kka2_1:2_N195I,kka2_1:2_195,Kka2,kka2_1:2,P00552,0.185134,NO,195,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-0.836,-4.062,3.226,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.295029,0.00276134,0.185134 kka2_1:1_D62K,kka2_1:1_62,Kka2,kka2_1:1,P00552,0.185206,NO,62,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.591,-3.652,2.061,,0.262,H,A,0.75,0.08,10.048,10.048,64.39,PAA,-1.77833,0.520039,0.00744243,0.185206 beta-lactamase_625_M184K,beta-lactamase_625_184,TEM-1,beta-lactamase_625,P62593,0.185212,NO,184,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.593,-3.659,2.066,,,H,A,0.55,-0.87,2.765,,62.94,HHH,-1.41,0.213352,0.00356019,0.185212 kka2_1:1_L47D,kka2_1:1_47,Kka2,kka2_1:1,P00552,0.185332,NO,47,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.265,-4.048,2.783,,0.139,E,B,0.55,-0.86,14.593,14.593,63.26,HHH,-1.77933,0.520039,0.00509386,0.185332 beta-lactamase_156_G234Q,beta-lactamase_156_234,TEM-1,beta-lactamase_156,P62593,0.185335,NO,234,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.62,-4.124,3.504,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.111618,0.000889577,0.185335 kka2_1:2_N195G,kka2_1:2_195,Kka2,kka2_1:2,P00552,0.185363,NO,195,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-0.836,-2.98,2.144,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.295029,0.00276134,0.185363 beta-lactamase_156_A132R,beta-lactamase_156_132,TEM-1,beta-lactamase_156,P62593,0.185373,NO,132,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.9,-3.795,2.895,,,H,A,0.46,-0.93,10.621,,64.69,PHH,-1.138,0.111618,0.000962524,0.185373 beta-lactamase_156_L74R,beta-lactamase_156_74,TEM-1,beta-lactamase_156,P62593,0.185387,NO,74,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.296,-3.939,2.643,,,H,A,0.55,-0.91,0.746,,50,HHO,-1.34933,0.111618,0.00493255,0.185387 kka2_1:1_W236I,kka2_1:1_236,Kka2,kka2_1:1,P00552,0.185389,NO,236,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-1.363,-3.761,2.398,,0.303,H,A,1.51,-0.76,12.263,12.263,48.48,AHH,-1.81267,0.520039,0.0088796,0.185389 Pab1_I128P,Pab1_128,Pab1,Pab1,P04147,0.18541,NO,128,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.345,-3.918,2.573,,0.008,E,B,1.68,-0.6,1.706,,78.68,PHH,-1.231,0.175299,0.00104192,0.18541 beta-lactamase_625_W227V,beta-lactamase_625_227,TEM-1,beta-lactamase_625,P62593,0.185432,NO,227,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-0.982,-3.747,2.765,,0.272,,B,0.47,-0.29,2.533,,74.48,OHH,-1.595,0.213352,0.00226019,0.185432 Ubiquitin_G75V,Ubiquitin_75,Uba1,Ubiquitin,P0CG48,0.185484,NO,75,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.613,-3.659,2.046,5.44099,0.552,T,A,0.73,0.9,4.017,,34.31,BOO,-1.66767,0.205827,0.000712673,0.185484 Ubiquitin_I44Q,Ubiquitin_44,Uba1,Ubiquitin,P0CG48,0.185484,NO,44,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.566,-4.128,2.562,4.71256,,E,B,0.27,-1.17,5.26,,39.71,HHH,-1.38567,0.205827,0.000613305,0.185484 beta-lactamase_625_M209K,beta-lactamase_625_209,TEM-1,beta-lactamase_625,P62593,0.185504,NO,209,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.442,-3.673,2.231,,,H,A,0.55,-0.97,1.167,,64.69,HHA,-1.52633,0.213352,0.00625021,0.185504 beta-lactamase_2500_D155H,beta-lactamase_2500_155,TEM-1,beta-lactamase_2500,P62593,0.185529,NO,155,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.889,-4.424,3.535,,0.049,,B,0.75,-0.9,2.386,,64.69,OAB,-1.62267,0.361275,0.00135315,0.185529 beta-lactamase_2500_T179L,beta-lactamase_2500_179,TEM-1,beta-lactamase_2500,P62593,0.185531,NO,179,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.085,-3.263,2.178,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.361275,0.00226045,0.185531 beta-lactamase_2500_L218R,beta-lactamase_2500_218,TEM-1,beta-lactamase_2500,P62593,0.185589,NO,218,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.391,-2.276,0.885,,,I,b,0.55,-0.53,9.151,9.151,74.48,OHH,-1.58867,0.361275,0.00618274,0.185589 kka2_1:2_L184H,kka2_1:2_184,Kka2,kka2_1:2,P00552,0.185621,NO,184,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.496,-4.936,3.44,,0.489,E,B,0.55,-0.06,14.044,14.044,63.26,AHH,-1.24833,0.295029,0.00518742,0.185621 beta-lactamase_625_G240I,beta-lactamase_625_240,TEM-1,beta-lactamase_625,P62593,0.185629,NO,240,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.213352,0.00591201,0.185629 beta-lactamase_2500_I244G,beta-lactamase_2500_244,TEM-1,beta-lactamase_2500,P62593,0.185737,NO,244,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.555,-3.714,2.159,,,E,B,0.48,-0.84,1.683,,77.62,OHH,-1.385,0.361275,0.00605379,0.185737 kka2_1:1_L170Q,kka2_1:1_170,Kka2,kka2_1:1,P00552,0.185754,NO,170,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.28,-4.219,2.939,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.520039,0.00730791,0.185754 beta-lactamase_156_L136K,beta-lactamase_156_136,TEM-1,beta-lactamase_156,P62593,0.185796,NO,136,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.232,-3.824,2.592,,,H,A,0.55,-0.34,1.04,,48.95,HHH,-1.088,0.111618,0.00442304,0.185796 beta-lactamase_625_I245N,beta-lactamase_625_245,TEM-1,beta-lactamase_625,P62593,0.185804,NO,245,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.213352,0.00391032,0.185804 kka2_1:4_C209W,kka2_1:4_209,Kka2,kka2_1:4,P00552,0.18584,NO,209,C,W,CW,Special,Hydrophobic,5.07,5.89,0.82,215,121,204,83,108.5,227.8,119.3,-0.906,-5.149,4.243,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.168804,0.00260862,0.18584 kka2_1:1_L57E,kka2_1:1_57,Kka2,kka2_1:1,P00552,0.185857,NO,57,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.898,-3.855,1.957,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.520039,0.00723769,0.185857 beta-lactamase_625_A215I,beta-lactamase_625_215,TEM-1,beta-lactamase_625,P62593,0.185889,NO,215,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.503,-3.916,2.413,,,,a,0.46,-0.93,3.583,,74.48,HHO,-1.42633,0.213352,0.00544007,0.185889 beta-lactamase_2500_R159D,beta-lactamase_2500_159,TEM-1,beta-lactamase_2500,P62593,0.185898,NO,159,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-0.94,-3.691,2.751,,0.316,,B,1.2,-0.55,2.341,,64.34,PBH,-1.011,0.361275,0.00108472,0.185898 beta-lactamase_2500_T126P,beta-lactamase_2500_126,TEM-1,beta-lactamase_2500,P62593,0.185927,NO,126,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.122,-3.758,2.636,,0.05,H,A,0.22,-0.05,0.817,,44.41,HPH,-1.60467,0.361275,0.00244552,0.185927 kka2_1:4_G189M,kka2_1:4_189,Kka2,kka2_1:4,P00552,0.185932,NO,189,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.596,-4.958,4.362,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.168804,0.00253688,0.185932 beta-lactamase_625_I280H,beta-lactamase_625_280,TEM-1,beta-lactamase_625,P62593,0.185937,NO,280,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.213352,0.0530888,0.185937 beta-lactamase_625_I125P,beta-lactamase_625_125,TEM-1,beta-lactamase_625,P62593,0.18605,NO,125,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.441,-4.116,2.675,,,H,A,0.48,-0.7,2.034,,63.29,HHP,-1.248,0.213352,0.00383964,0.18605 kka2_1:2_G99W,kka2_1:2_99,Kka2,kka2_1:2,P00552,0.186165,NO,99,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.596,-5.126,4.53,,0.368,S,g,0.29,-0.87,,,,OOP,-1.63067,0.295029,0.00186055,0.186165 kka2_1:4_L259E,kka2_1:4_259,Kka2,kka2_1:4,P00552,0.186179,NO,259,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.088,-3.851,2.763,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.168804,0.0206964,0.186179 kka2_1:2_S104W,kka2_1:2_104,Kka2,kka2_1:2,P00552,0.186188,NO,104,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.436,-5.482,4.046,,0.536,T,A,0.27,-1.11,5.49,,63.64,HPP,-1.91433,0.295029,0.00555207,0.186188 kka2_1:1_C31I,kka2_1:1_31,Kka2,kka2_1:1,P00552,0.186242,NO,31,C,I,CI,Special,Hydrophobic,5.07,6.02,0.95,198,121,131,10,108.5,166.7,58.2,-2.246,-3.907,1.661,,1.152,S,b,0.46,4.16,8.272,,63.26,OOP,-1.21533,0.520039,0.00681582,0.186242 PSD95pdz3_L379Q,PSD95pdz3_379,PSD95pdz3,PSD95pdz3,P31016,0.186264,NO,379,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.347,-3.806,2.459,5.37777,,,,,16.8762,,,,HHB,-1.35667,0.0758425,0.00029733,0.186264 beta-lactamase_2500_M66Y,beta-lactamase_2500_66,TEM-1,beta-lactamase_2500,P62593,0.186267,NO,66,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.362,-4.034,2.672,,0.013,,A,0.55,-0.7,0.502,,73.08,OHH,-1.49567,0.361275,0.00412876,0.186267 Pab1_L142G,Pab1_142,Pab1,Pab1,P04147,0.18629,NO,142,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.039,-3.625,2.586,,0.007,H,A,0.84,-0.65,,,,HHH,-1.487,0.175299,0.000335477,0.18629 beta-lactamase_625_I206P,beta-lactamase_625_206,TEM-1,beta-lactamase_625,P62593,0.186327,NO,206,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-2.429,-4.04,1.611,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.213352,0.00528934,0.186327 PSD95pdz3_I359Y,PSD95pdz3_359,PSD95pdz3,PSD95pdz3,P31016,0.186327,NO,359,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.63,-3.619,1.989,5.35151,,,,,14.8012,,,,PHH,-1.58667,0.0758425,0.000580694,0.186327 beta-lactamase_2500_I229W,beta-lactamase_2500_229,TEM-1,beta-lactamase_2500,P62593,0.186377,NO,229,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.267,-5.365,4.098,,0.083,E,B,0.48,-0.76,3.875,,50,HHH,-1.58767,0.361275,0.00477249,0.186377 kka2_1:4_G210H,kka2_1:4_210,Kka2,kka2_1:4,P00552,0.186413,NO,210,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.095,-4.794,3.699,,0.103,T,A,0.29,-0.62,0.271,,50,OOB,-0.966667,0.168804,0.00598378,0.186413 kka2_1:4_G213M,kka2_1:4_213,Kka2,kka2_1:4,P00552,0.186449,NO,213,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.596,-4.958,4.362,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.168804,0.00187654,0.186449 hsp90_G584L,hsp90_584,hsp90,hsp90,P02829,0.186462,NO,584,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-2.511,-2.511,0,5.20094,0.414,S,b,0.84,0.33,,,,HOH,-3.32733,0.368192,0.000222939,0.186462 beta-lactamase_2500_D177M,beta-lactamase_2500_177,TEM-1,beta-lactamase_2500,P62593,0.186473,NO,177,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.967,-4.928,3.961,,0.006,T,L,0.75,-1.02,4.131,,64.69,BAP,-0.873667,0.361275,0.000864022,0.186473 beta-lactamase_2500_E119L,beta-lactamase_2500_119,TEM-1,beta-lactamase_2500,P62593,0.186532,NO,119,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.412,-3.669,2.257,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.361275,0.00386966,0.186532 kka2_1:4_G189P,kka2_1:4_189,Kka2,kka2_1:4,P00552,0.186537,NO,189,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.596,-3.908,3.312,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.168804,0.00253688,0.186537 kka2_1:2_A144M,kka2_1:2_144,Kka2,kka2_1:2,P00552,0.186556,NO,144,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.859,-4.454,3.595,,,H,A,0.46,0.21,6.844,,52.65,BHB,-1.72933,0.295029,0.00231095,0.186556 beta-lactamase_39_M184D,beta-lactamase_39_184,TEM-1,beta-lactamase_39,P62593,0.186594,NO,184,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.593,-3.936,2.343,,,H,A,0.55,-0.87,2.893,,62.94,HHH,-1.41,0.0495842,0.00356019,0.186594 beta-lactamase_39_D129P,beta-lactamase_39_129,TEM-1,beta-lactamase_39,P62593,0.186616,NO,129,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.816,-3.68,2.864,,,,B,0.75,-0.69,0.56,,34.97,PAP,-0.818,0.0495842,0.00109178,0.186616 beta-lactamase_2500_K232T,beta-lactamase_2500_232,TEM-1,beta-lactamase_2500,P62593,0.186649,NO,232,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.012,-3.464,2.452,,,E,B,2.34,-1.1,3.048,,65.03,ABP,-1.238,0.361275,0.00313441,0.186649 beta-lactamase_625_V260Y,beta-lactamase_625_260,TEM-1,beta-lactamase_625,P62593,0.186772,NO,260,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.101,-3.316,2.215,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.213352,0.00471757,0.186772 beta-lactamase_2500_M115E,beta-lactamase_2500_115,TEM-1,beta-lactamase_2500,P62593,0.186795,NO,115,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.389,-3.76,2.371,,0.019,E,B,0.55,0.08,3.261,,69.58,OHP,-1.25433,0.361275,0.0034337,0.186795 beta-lactamase_2500_G234V,beta-lactamase_2500_234,TEM-1,beta-lactamase_2500,P62593,0.186812,NO,234,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.62,-3.754,3.134,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.361275,0.000889577,0.186812 beta-lactamase_625_I125Y,beta-lactamase_625_125,TEM-1,beta-lactamase_625,P62593,0.186853,NO,125,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.441,-4.111,2.67,,,H,A,0.48,-0.7,2.034,,63.29,HHP,-1.248,0.213352,0.00383964,0.186853 beta-lactamase_2500_D207P,beta-lactamase_2500_207,TEM-1,beta-lactamase_2500,P62593,0.186861,NO,207,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.064,-3.955,1.891,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.361275,0.00592942,0.186861 kka2_1:4_I228N,kka2_1:4_228,Kka2,kka2_1:4,P00552,0.186873,NO,228,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.142,-4.223,3.081,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.168804,0.00458834,0.186873 kka2_1:1_G189N,kka2_1:1_189,Kka2,kka2_1:1,P00552,0.186882,NO,189,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.596,-3.476,2.88,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.520039,0.00253688,0.186882 kka2_1:1_D134R,kka2_1:1_134,Kka2,kka2_1:1,P00552,0.1869,NO,134,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.969,-3.942,2.973,,0.421,B,B,0.75,0.31,2.329,,49.62,HAB,-1.057,0.520039,0.00270812,0.1869 WW_domain_K181P,WW_domain_181,Yap65,WW_domain,P46937,0.186914,NO,181,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.35,-3.646,2.296,5.0864,,,,,,0.176,,15.87,HBP,-1.247,0.153962,0.0033022,0.186914 kka2_1:2_Y244G,kka2_1:2_244,Kka2,kka2_1:2,P00552,0.186927,NO,244,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-0.775,-3.611,2.836,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.295029,0.00453187,0.186927 beta-lactamase_2500_C121W,beta-lactamase_2500_121,TEM-1,beta-lactamase_2500,P62593,0.186932,NO,121,C,W,CW,Special,Hydrophobic,5.07,5.89,0.82,215,121,204,83,108.5,227.8,119.3,-0.953,-5.146,4.193,,,H,A,0.46,-0.81,1.174,,63.29,HOP,-1.46767,0.361275,0.000744322,0.186932 beta-lactamase_2500_R59Y,beta-lactamase_2500_59,TEM-1,beta-lactamase_2500,P62593,0.186945,NO,59,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.345,-4.267,2.922,,0.329,S,L,1.2,-0.09,3.719,,73.08,HBO,-2.24267,0.361275,0.00318082,0.186945 kka2_1:2_V80H,kka2_1:2_80,Kka2,kka2_1:2,P00552,0.186952,NO,80,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.144,-4.98,3.836,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.295029,0.00488211,0.186952 beta-lactamase_2500_I277E,beta-lactamase_2500_277,TEM-1,beta-lactamase_2500,P62593,0.186962,NO,277,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.869,-4.006,2.137,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.361275,0.0169305,0.186962 kka2_1:2_L212K,kka2_1:2_212,Kka2,kka2_1:2,P00552,0.186962,NO,212,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.904,-3.732,2.828,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.295029,0.0031426,0.186962 Pab1_I152R,Pab1_152,Pab1,Pab1,P04147,0.187044,NO,152,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.345,-4.051,2.706,,0.165,E,B,1.23,-0.71,1.288,,71.4,AHH,-1.59433,0.175299,0.000740963,0.187044 kka2_1:1_A222M,kka2_1:1_222,Kka2,kka2_1:1,P00552,0.187057,NO,222,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.725,-4.508,3.783,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.520039,0.00207657,0.187057 beta-lactamase_2500_Y262R,beta-lactamase_2500_262,TEM-1,beta-lactamase_2500,P62593,0.187121,NO,262,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.361275,0.00853516,0.187121 kka2_1:4_V49F,kka2_1:4_49,Kka2,kka2_1:4,P00552,0.187146,NO,49,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.614,-3.894,2.28,,,E,B,0.44,-0.77,1.233,,64.39,HHB,-1.3,0.168804,0.00615685,0.187146 kka2_1:1_K138D,kka2_1:1_138,Kka2,kka2_1:1,P00552,0.187204,NO,138,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-2.5,-2.178,-0.322,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.520039,0.00628542,0.187204 beta-lactamase_625_I245H,beta-lactamase_625_245,TEM-1,beta-lactamase_625,P62593,0.187233,NO,245,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.213352,0.00391032,0.187233 beta-lactamase_156_G249V,beta-lactamase_156_249,TEM-1,beta-lactamase_156,P62593,0.187257,NO,249,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.111618,0.00220169,0.187257 beta-lactamase_2500_D161F,beta-lactamase_2500_161,TEM-1,beta-lactamase_2500,P62593,0.187266,NO,161,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.891,-4.316,3.425,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.361275,0.000897697,0.187266 kka2_1:2_G189M,kka2_1:2_189,Kka2,kka2_1:2,P00552,0.187317,NO,189,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.596,-4.958,4.362,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.295029,0.00253688,0.187317 beta-lactamase_156_I245Q,beta-lactamase_156_245,TEM-1,beta-lactamase_156,P62593,0.187323,NO,245,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.111618,0.00391032,0.187323 kka2_1:4_R211F,kka2_1:4_211,Kka2,kka2_1:4,P00552,0.187353,NO,211,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-0.899,-4.206,3.307,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.168804,0.00204888,0.187353 beta-lactamase_2500_I245D,beta-lactamase_2500_245,TEM-1,beta-lactamase_2500,P62593,0.187391,NO,245,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.361275,0.00391032,0.187391 beta-lactamase_A16A,beta-lactamase_16,TEM-1,beta-lactamase,P62593,0.187435,NO,16,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,,,,,,,,,,,,,HHH,,0.221079,0.00245392,0.187435 beta-lactamase_E164D,beta-lactamase_164,TEM-1,beta-lactamase,P62593,0.187435,NO,164,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-0.948,-2.949,2.001,5.3334,0.011,T,B,1.62,-0.4,1.055,,64.69,HAO,-1.388,0.221079,0.00137286,0.187435 beta-lactamase_G248F,beta-lactamase_248,TEM-1,beta-lactamase,P62593,0.187435,NO,248,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.794,-4.03,2.236,4.69798,,E,b,0.23,-0.43,1.782,,61.19,HOO,-1.52867,0.221079,0.00428493,0.187435 beta-lactamase_N272W,beta-lactamase_272,TEM-1,beta-lactamase,P62593,0.187435,NO,272,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-1.127,-5.578,4.451,5.37826,0.081,H,A,0.09,-0.97,1.468,,63.64,BPB,-1.56333,0.221079,0.00545371,0.187435 beta-lactamase_625_M209T,beta-lactamase_625_209,TEM-1,beta-lactamase_625,P62593,0.187448,NO,209,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.442,-3.52,2.078,,,H,A,0.55,-0.97,1.167,,64.69,HHA,-1.52633,0.213352,0.00625021,0.187448 kka2_1:1_T72F,kka2_1:1_72,Kka2,kka2_1:1,P00552,0.187449,NO,72,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.38,-4.46,2.08,,0.784,H,A,0.22,0.29,10.43,10.43,65.53,HPP,-2.238,0.520039,0.00750756,0.187449 beta-lactamase_625_A34D,beta-lactamase_625_34,TEM-1,beta-lactamase_625,P62593,0.187504,NO,34,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.059,-3.876,1.817,,,H,A,0.46,-0.54,3.614,,73.78,AHA,-1.74967,0.213352,0.00407913,0.187504 beta-lactamase_2500_L146S,beta-lactamase_2500_146,TEM-1,beta-lactamase_2500,P62593,0.187507,NO,146,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.462,-2.916,1.454,,0.007,H,A,0.55,-0.56,1.578,,64.69,AHP,-1.656,0.361275,0.00474542,0.187507 kka2_1:2_W15M,kka2_1:2_15,Kka2,kka2_1:2,P00552,0.187535,NO,15,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-1.392,-4.272,2.88,,0.01,G,A,0.47,0.15,2.586,,52.27,HHH,-2.10533,0.295029,0.00585505,0.187535 beta-lactamase_156_L167Y,beta-lactamase_156_167,TEM-1,beta-lactamase_156,P62593,0.187589,NO,167,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.138,-4.067,2.929,,0.015,G,A,0.55,-0.63,0.4,,64.69,AHP,-1.30767,0.111618,0.00303566,0.187589 beta-lactamase_2500_I140P,beta-lactamase_2500_140,TEM-1,beta-lactamase_2500,P62593,0.187606,NO,140,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.733,-4.152,2.419,,0.128,H,A,0.48,0.41,1.628,,73.08,PHO,-1.48733,0.361275,0.00597777,0.187606 beta-lactamase_2500_I45D,beta-lactamase_2500_45,TEM-1,beta-lactamase_2500,P62593,0.18762,NO,45,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-2.421,-3.902,1.481,,,E,B,0.48,-0.3,3.793,,77.62,HHA,-2.30267,0.361275,0.00452842,0.18762 kka2_1:2_L103N,kka2_1:2_103,Kka2,kka2_1:2,P00552,0.187685,NO,103,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-2.362,-3.939,1.577,,0.394,T,A,0.55,-0.99,3.499,,63.64,HHP,-1.534,0.295029,0.00574792,0.187685 kka2_1:1_H188K,kka2_1:1_188,Kka2,kka2_1:1,P00552,0.187723,NO,188,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-0.913,-3.453,2.54,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.520039,0.00273139,0.187723 beta-lactamase_625_I229N,beta-lactamase_625_229,TEM-1,beta-lactamase_625,P62593,0.187744,NO,229,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.267,-4.128,2.861,,0.083,E,B,0.48,-0.76,1.69,,50,HHH,-1.58767,0.213352,0.00477249,0.187744 kka2_1:2_N200P,kka2_1:2_200,Kka2,kka2_1:2,P00552,0.18784,NO,200,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-2.446,-4.046,1.6,,0.756,T,L,0.61,-0.08,2.836,,64.39,APO,-2.08,0.295029,0.00838549,0.18784 kka2_1:8_Y22P,kka2_1:8_22,Kka2,kka2_1:8,P00552,0.187859,NO,22,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-1.583,-4.113,2.53,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.100394,0.00598977,0.187859 kka2_1:8_Y22P,kka2_1:8_22,Kka2,kka2_1:8,P00552,0.187859,NO,22,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-1.583,-4.113,2.53,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.100394,0.00598977,0.187859 beta-lactamase_156_V72Y,beta-lactamase_156_72,TEM-1,beta-lactamase_156,P62593,0.187869,NO,72,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.658,-4.055,2.397,,,H,A,0.44,-1.03,1.92,,65.73,BHH,-1.32167,0.111618,0.00501194,0.187869 beta-lactamase_39_D177F,beta-lactamase_39_177,TEM-1,beta-lactamase_39,P62593,0.187989,NO,177,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.967,-4.34,3.373,,0.006,T,L,0.75,-1.02,3.536,,64.69,BAP,-0.873667,0.0495842,0.000864022,0.187989 beta-lactamase_2500_V117K,beta-lactamase_2500_117,TEM-1,beta-lactamase_2500,P62593,0.188023,NO,117,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.53,-3.844,2.314,,,H,A,0.44,-0.34,1.23,,65.03,PHB,-1.741,0.361275,0.00467906,0.188023 beta-lactamase_2500_A230D,beta-lactamase_2500_230,TEM-1,beta-lactamase_2500,P62593,0.18803,NO,230,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.154,-3.645,2.491,,0.01,E,B,0.46,-1.17,1.171,,50,HHA,-1.079,0.361275,0.00516841,0.18803 beta-lactamase_2500_L137P,beta-lactamase_2500_137,TEM-1,beta-lactamase_2500,P62593,0.188103,NO,137,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.03,-4.134,3.104,,,H,A,0.55,-0.38,0.769,,42.31,HHP,-1.58933,0.361275,0.00278599,0.188103 kka2_1:1_L103N,kka2_1:1_103,Kka2,kka2_1:1,P00552,0.188106,NO,103,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-2.362,-3.939,1.577,,0.394,T,A,0.55,-0.99,4.121,,63.64,HHP,-1.534,0.520039,0.00574792,0.188106 kka2_1:4_F203G,kka2_1:4_203,Kka2,kka2_1:4,P00552,0.188168,NO,203,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-0.911,-3.675,2.764,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.168804,0.00318738,0.188168 beta-lactamase_2500_M153P,beta-lactamase_2500_153,TEM-1,beta-lactamase_2500,P62593,0.188218,NO,153,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-3.193,-4.07,0.877,,0.14,T,A,0.55,-0.11,3.409,,77.62,PHO,-2.25767,0.361275,0.00509109,0.188218 beta-lactamase_39_S68F,beta-lactamase_39_68,TEM-1,beta-lactamase_39,P62593,0.188226,NO,68,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-0.913,-4.116,3.203,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.0495842,0.000800065,0.188226 kka2_1:2_F171E,kka2_1:2_171,Kka2,kka2_1:2,P00552,0.188308,NO,171,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.326,-3.96,2.634,,0.154,H,A,0.58,-0.1,2.645,,63.64,HHH,-1.45433,0.295029,0.00821426,0.188308 kka2_1:4_I246P,kka2_1:4_246,Kka2,kka2_1:4,P00552,0.188321,NO,246,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-2.008,-3.255,1.247,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.168804,0.0139479,0.188321 beta-lactamase_625_T69K,beta-lactamase_625_69,TEM-1,beta-lactamase_625,P62593,0.188405,NO,69,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-0.973,-3.493,2.52,,,G,A,0.22,-1.24,2.716,,93.01,PPH,-1.01833,0.213352,0.00127498,0.188405 kka2_1:8_F240I,kka2_1:8_240,Kka2,kka2_1:8,P00552,0.188443,NO,240,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-0.911,-3.319,2.408,,,H,A,1.62,-1.21,0.697,,50.38,BHH,-1.67267,0.100394,0.00552543,0.188443 kka2_1:8_F240I,kka2_1:8_240,Kka2,kka2_1:8,P00552,0.188443,NO,240,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-0.911,-3.319,2.408,,,H,A,1.62,-1.21,0.697,,50.38,BHH,-1.67267,0.100394,0.00552543,0.188443 kka2_1:2_A237R,kka2_1:2_237,Kka2,kka2_1:2,P00552,0.188466,NO,237,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.12,-4.175,2.055,,0.068,H,A,0.46,-0.71,2.369,,92.05,HHA,-2.10433,0.295029,0.012257,0.188466 beta-lactamase_2500_V78S,beta-lactamase_2500_78,TEM-1,beta-lactamase_2500,P62593,0.188545,NO,78,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.459,-3.701,2.242,,,H,A,0.44,-0.47,31.376,31.376,63.64,HHH,-1.17833,0.361275,0.00492501,0.188545 beta-lactamase_2500_R257W,beta-lactamase_2500_257,TEM-1,beta-lactamase_2500,P62593,0.188556,NO,257,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.361275,0.00756629,0.188556 beta-lactamase_2500_E35N,beta-lactamase_2500_35,TEM-1,beta-lactamase_2500,P62593,0.188565,NO,35,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-0.869,-3.445,2.576,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.361275,0.00174441,0.188565 beta-lactamase_625_A185L,beta-lactamase_625_185,TEM-1,beta-lactamase_625,P62593,0.188568,NO,185,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.406,-2.064,0.658,,,H,A,0.46,-1.02,0.365,,65.03,HHP,-1.84033,0.213352,0.00467449,0.188568 beta-lactamase_2500_A230N,beta-lactamase_2500_230,TEM-1,beta-lactamase_2500,P62593,0.188583,NO,230,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.154,-3.731,2.577,,0.01,E,B,0.46,-1.17,1.171,,50,HHA,-1.079,0.361275,0.00516841,0.188583 kka2_1:1_G205W,kka2_1:1_205,Kka2,kka2_1:1,P00552,0.188599,NO,205,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.596,-5.126,4.53,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.520039,0.00221855,0.188599 beta-lactamase_625_N130M,beta-lactamase_625_130,TEM-1,beta-lactamase_625,P62593,0.188604,NO,130,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-0.798,-4.705,3.907,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.213352,0.000683376,0.188604 beta-lactamase_2500_A124N,beta-lactamase_2500_124,TEM-1,beta-lactamase_2500,P62593,0.188647,NO,124,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.181,-3.812,2.631,,,H,A,0.46,-0.9,0.314,,64.34,HHH,-1.152,0.361275,0.00481399,0.188647 kka2_1:1_A78Y,kka2_1:1_78,Kka2,kka2_1:1,P00552,0.18873,NO,78,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.744,-4.391,2.647,,0.078,.,B,0.46,-0.53,0.206,,56.06,OHH,-1.863,0.520039,0.00457299,0.18873 beta-lactamase_156_F64S,beta-lactamase_156_64,TEM-1,beta-lactamase_156,P62593,0.188747,NO,64,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-0.841,-3.611,2.77,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.111618,0.000947691,0.188747 beta-lactamase_156_E62P,beta-lactamase_156_62,TEM-1,beta-lactamase_156,P62593,0.188769,NO,62,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.193,-3.775,2.582,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.111618,0.00264802,0.188769 beta-lactamase_2500_G236W,beta-lactamase_2500_236,TEM-1,beta-lactamase_2500,P62593,0.188816,NO,236,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.784,-5.189,4.405,,0.241,,b,0.29,-0.59,2.14,,64.69,HOO,-1.025,0.361275,0.00162372,0.188816 kka2_1:8_T187H,kka2_1:8_187,Kka2,kka2_1:8,P00552,0.188832,NO,187,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.273,-4.848,3.575,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.100394,0.00693073,0.188832 kka2_1:8_T187H,kka2_1:8_187,Kka2,kka2_1:8,P00552,0.188832,NO,187,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.273,-4.848,3.575,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.100394,0.00693073,0.188832 beta-lactamase_39_W227R,beta-lactamase_39_227,TEM-1,beta-lactamase_39,P62593,0.18885,NO,227,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-0.982,-4.182,3.2,,0.272,,B,0.47,-0.29,1.37,,74.48,OHH,-1.595,0.0495842,0.00226019,0.18885 kka2_1:1_G189K,kka2_1:1_189,Kka2,kka2_1:1,P00552,0.188891,NO,189,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.596,-3.71,3.114,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.520039,0.00253688,0.188891 kka2_1:1_H188F,kka2_1:1_188,Kka2,kka2_1:1,P00552,0.188904,NO,188,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-0.913,-3.931,3.018,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.520039,0.00273139,0.188904 beta-lactamase_2500_W227Q,beta-lactamase_2500_227,TEM-1,beta-lactamase_2500,P62593,0.188924,NO,227,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-0.982,-4.194,3.212,,0.272,,B,0.47,-0.29,1.37,,74.48,OHH,-1.595,0.361275,0.00226019,0.188924 kka2_1:4_L107W,kka2_1:4_107,Kka2,kka2_1:4,P00552,0.188936,NO,107,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.238,-5.321,4.083,,0.197,.,B,0.55,-1.1,0.398,,71.59,BHH,-2.143,0.168804,0.00561937,0.188936 kka2_1:8_V186H,kka2_1:8_186,Kka2,kka2_1:8,P00552,0.189027,NO,186,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.011,-4.974,3.963,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.100394,0.00409703,0.189027 kka2_1:8_V186H,kka2_1:8_186,Kka2,kka2_1:8,P00552,0.189027,NO,186,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.011,-4.974,3.963,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.100394,0.00409703,0.189027 beta-lactamase_2500_N134V,beta-lactamase_2500_134,TEM-1,beta-lactamase_2500,P62593,0.189039,NO,134,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-0.879,-3.751,2.872,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.361275,0.000644786,0.189039 beta-lactamase_625_T193P,beta-lactamase_625_193,TEM-1,beta-lactamase_625,P62593,0.189068,NO,193,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.914,-4.072,2.158,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.213352,0.00482669,0.189068 kka2_1:2_F264D,kka2_1:2_264,Kka2,kka2_1:2,P00552,0.189106,NO,264,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.02,-4.038,3.018,,0.296,.,?,0.58,0.02,2.303,,71.59,HHNA,-0.9655,0.295029,,0.189106 kka2_1:4_G30F,kka2_1:4_30,Kka2,kka2_1:4,P00552,0.189192,NO,30,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.596,-4.32,3.724,,0.54,S,g,0.29,3.76,,,,HOO,-1.51133,0.168804,0.00159208,0.189192 kka2_1:2_R66W,kka2_1:2_66,Kka2,kka2_1:2,P00552,0.189205,NO,66,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-0.922,-5.385,4.463,,0.103,H,A,1.2,-0.2,2.659,,46.21,HBH,-1.13567,0.295029,0.00161025,0.189205 E1_Ubiquitin_G75R,E1_Ubiquitin_75,Uba1,E1_Ubiquitin,P0CG63,0.189213,NO,75,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.999,-2.3,1.301,,0.552,T,A,0.75,0.9,4.369,,83.73,BOO,-1.1,0.18783,0.00153276,0.189213 E1_Ubiquitin_L73D,E1_Ubiquitin_73,Uba1,E1_Ubiquitin,P0CG63,0.189213,NO,73,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.039,-3.961,2.922,,0.518,,B,1.3,1,,,,BHB,-1.175,0.18783,0.00111236,0.189213 kka2_1:1_A255L,kka2_1:1_255,Kka2,kka2_1:1,P00552,0.189263,NO,255,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.715,-3.015,1.3,,0.466,H,A,0.46,-0.52,0.946,,65.53,HHH,-1.71267,0.520039,0.0126809,0.189263 beta-lactamase_156_G240P,beta-lactamase_156_240,TEM-1,beta-lactamase_156,P62593,0.189294,NO,240,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.111618,0.00591201,0.189294 kka2_1:2_A222N,kka2_1:2_222,Kka2,kka2_1:2,P00552,0.189304,NO,222,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.725,-3.926,3.201,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.295029,0.00207657,0.189304 beta-lactamase_156_D129Q,beta-lactamase_156_129,TEM-1,beta-lactamase_156,P62593,0.189306,NO,129,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.816,-3.637,2.821,,,,B,0.75,-0.69,1.924,,34.97,PAP,-0.818,0.111618,0.00109178,0.189306 Pab1_V171D,Pab1_171,Pab1,Pab1,P04147,0.189373,NO,171,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.113,-3.736,2.623,,0.008,E,b,0.23,-0.34,,,,HHB,-1.19733,0.175299,0.000298662,0.189373 kka2_1:8_L223H,kka2_1:8_223,Kka2,kka2_1:8,P00552,0.189415,NO,223,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.861,-4.978,4.117,,,H,A,1.59,-1.24,1.017,,50,HHH,-0.854333,0.100394,0.00253574,0.189415 kka2_1:8_L223H,kka2_1:8_223,Kka2,kka2_1:8,P00552,0.189415,NO,223,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.861,-4.978,4.117,,,H,A,1.59,-1.24,1.017,,50,HHH,-0.854333,0.100394,0.00253574,0.189415 kka2_1:1_V153H,kka2_1:1_153,Kka2,kka2_1:1,P00552,0.189437,NO,153,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.092,-4.991,3.899,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.520039,0.00501119,0.189437 beta-lactamase_625_V31K,beta-lactamase_625_31,TEM-1,beta-lactamase_625,P62593,0.189458,NO,31,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.822,-3.873,2.051,,,H,A,0.44,-0.46,2.576,,73.78,BHB,-2.03767,0.213352,0.00478065,0.189458 beta-lactamase_39_L136D,beta-lactamase_39_136,TEM-1,beta-lactamase_39,P62593,0.189468,NO,136,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.232,-4.137,2.905,,,H,A,0.55,-0.34,0.336,,48.95,HHH,-1.088,0.0495842,0.00442304,0.189468 beta-lactamase_625_K232G,beta-lactamase_625_232,TEM-1,beta-lactamase_625,P62593,0.189586,NO,232,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.012,-3.401,2.389,,,E,B,2.34,-1.1,1.992,,65.03,ABP,-1.238,0.213352,0.00313441,0.189586 kka2_1:2_I207Y,kka2_1:2_207,Kka2,kka2_1:2,P00552,0.189604,NO,207,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.175,-4.053,2.878,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.295029,0.00611824,0.189604 beta-lactamase_156_D155R,beta-lactamase_156_155,TEM-1,beta-lactamase_156,P62593,0.189638,NO,155,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.889,-3.873,2.984,,0.049,,B,0.75,-0.9,0.315,,64.69,OAB,-1.62267,0.111618,0.00135315,0.189638 beta-lactamase_V31H,beta-lactamase_31,TEM-1,beta-lactamase,P62593,0.189656,NO,31,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.822,-4.968,3.146,5.43781,,H,A,2.78,-0.46,2.885,,73.78,BHB,-2.03767,0.221079,0.00478065,0.189656 kka2_1:4_W236D,kka2_1:4_236,Kka2,kka2_1:4,P00552,0.189701,NO,236,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-1.363,-4.158,2.795,,0.303,H,A,0.47,-0.76,2.277,,48.48,AHH,-1.81267,0.168804,0.0088796,0.189701 kka2_1:4_C192K,kka2_1:4_192,Kka2,kka2_1:4,P00552,0.189715,NO,192,C,K,CK,Special,PositiveCharge,5.07,9.74,4.67,202,121,146,25,108.5,168.6,60.1,-1.067,-3.841,2.774,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.168804,0.00485428,0.189715 beta-lactamase_156_T69Y,beta-lactamase_156_69,TEM-1,beta-lactamase_156,P62593,0.189731,NO,69,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-0.973,-4.223,3.25,,,G,A,0.22,-1.24,4.194,,93.01,PPH,-1.01833,0.111618,0.00127498,0.189731 kka2_1:2_R217N,kka2_1:2_217,Kka2,kka2_1:2,P00552,0.189767,NO,217,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.158,-3.736,2.578,,0.252,T,A,1.2,-0.59,0.381,,52.27,ABH,-1.127,0.295029,0.0047191,0.189767 kka2_1:4_I141E,kka2_1:4_141,Kka2,kka2_1:4,P00552,0.189778,NO,141,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.495,-3.998,2.503,,0.068,H,A,0.48,-0.01,2.144,,92.05,BHA,-1.689,0.168804,0.00744745,0.189778 beta-lactamase_39_R162P,beta-lactamase_39_162,TEM-1,beta-lactamase_39,P62593,0.189796,NO,162,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.016,-2.671,1.655,,0.124,S,B,1.2,-0.37,31.656,31.656,64.69,ABH,-1.25,0.0495842,0.000561334,0.189796 kka2_1:4_G213T,kka2_1:4_213,Kka2,kka2_1:4,P00552,0.189799,NO,213,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.596,-3.675,3.079,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.168804,0.00187654,0.189799 beta-lactamase_625_I140D,beta-lactamase_625_140,TEM-1,beta-lactamase_625,P62593,0.18986,NO,140,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.733,-4.079,2.346,,0.128,H,A,0.48,0.41,1.628,,73.08,PHO,-1.48733,0.213352,0.00597777,0.18986 WW_domain_R203P,WW_domain_203,Yap65,WW_domain,P46937,0.189866,NO,203,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.539,-3.662,2.123,5.41321,,,,,,1.9,,70.04,OBO,-1.4695,0.153962,0.00172433,0.189866 beta-lactamase_625_W227G,beta-lactamase_625_227,TEM-1,beta-lactamase_625,P62593,0.189868,NO,227,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-0.982,-2.451,1.469,,0.272,,B,0.47,-0.29,2.533,,74.48,OHH,-1.595,0.213352,0.00226019,0.189868 kka2_1:1_F206H,kka2_1:1_206,Kka2,kka2_1:1,P00552,0.189883,NO,206,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.349,-4.415,3.066,,0.006,E,B,0.58,-1.21,0.978,,63.64,OHH,-1.04,0.520039,0.00936868,0.189883 kka2_1:4_H162P,kka2_1:4_162,Kka2,kka2_1:4,P00552,0.189891,NO,162,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-2.319,-4.047,1.728,,0.071,G,A,0.17,1.01,3.187,,64.39,ABP,-2.02067,0.168804,0.00616145,0.189891 beta-lactamase_156_L167R,beta-lactamase_156_167,TEM-1,beta-lactamase_156,P62593,0.189972,NO,167,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.138,-2.876,1.738,,0.015,G,A,0.55,-0.63,0.4,,64.69,AHP,-1.30767,0.111618,0.00303566,0.189972 beta-lactamase_2500_W227H,beta-lactamase_2500_227,TEM-1,beta-lactamase_2500,P62593,0.189995,NO,227,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-0.982,-4.704,3.722,,0.272,,B,0.47,-0.29,1.37,,74.48,OHH,-1.595,0.361275,0.00226019,0.189995 kka2_1:1_D183F,kka2_1:1_183,Kka2,kka2_1:1,P00552,0.190026,NO,183,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.204,-4.408,3.204,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.520039,0.00426304,0.190026 beta-lactamase_2500_L205Q,beta-lactamase_2500_205,TEM-1,beta-lactamase_2500,P62593,0.190045,NO,205,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.922,-4.179,3.257,,,H,A,0.55,-0.46,0.831,,42.31,PHH,-1.57767,0.361275,0.00255802,0.190045 beta-lactamase_625_D129T,beta-lactamase_625_129,TEM-1,beta-lactamase_625,P62593,0.190076,NO,129,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.816,-3.447,2.631,,,,B,0.75,-0.69,0.171,,34.97,PAP,-0.818,0.213352,0.00109178,0.190076 kka2_1:1_N200A,kka2_1:1_200,Kka2,kka2_1:1,P00552,0.190106,NO,200,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-2.446,-2.325,-0.121,,0.756,T,L,0.61,-0.08,17.299,17.299,64.39,APO,-2.08,0.520039,0.00838549,0.190106 kka2_1:1_P109H,kka2_1:1_109,Kka2,kka2_1:1,P00552,0.190128,NO,109,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.412,-3.364,1.952,,0.376,H,A,0.52,-1.25,18.506,18.506,65.53,HOH,-1.84567,0.520039,0.0070929,0.190128 beta-lactamase_G142L,beta-lactamase_142,TEM-1,beta-lactamase,P62593,0.19015,NO,142,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.707,-3.771,3.064,4.55474,0.034,,p,0.77,-0.64,1.947,,64.69,OOO,-0.834,0.221079,0.00060149,0.19015 kka2_1:1_L193H,kka2_1:1_193,Kka2,kka2_1:1,P00552,0.19015,NO,193,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.983,-4.891,3.908,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.520039,0.00480179,0.19015 beta-lactamase_156_P181K,beta-lactamase_156_181,TEM-1,beta-lactamase_156,P62593,0.190155,NO,181,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.813,-3.483,2.67,,,H,A,0.52,-1.14,1.078,,61.54,HOH,-1.795,0.111618,0.000703122,0.190155 kka2_1:1_I228H,kka2_1:1_228,Kka2,kka2_1:1,P00552,0.190158,NO,228,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.142,-5.006,3.864,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.520039,0.00458834,0.190158 kka2_1:1_A229H,kka2_1:1_229,Kka2,kka2_1:1,P00552,0.190166,NO,229,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.739,-3.451,1.712,,0.32,H,A,0.46,-0.7,6.549,,63.64,HHA,-1.851,0.520039,0.00942138,0.190166 beta-lactamase_2500_F64P,beta-lactamase_2500_64,TEM-1,beta-lactamase_2500,P62593,0.19032,NO,64,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-0.841,-4.33,3.489,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.361275,0.000947691,0.19032 beta-lactamase_2500_T107D,beta-lactamase_2500_107,TEM-1,beta-lactamase_2500,P62593,0.190353,NO,107,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.117,-3.478,2.361,,,G,A,0.22,-0.06,2.686,,67.83,HPA,-1.265,0.361275,0.00239347,0.190353 beta-lactamase_2500_L74D,beta-lactamase_2500_74,TEM-1,beta-lactamase_2500,P62593,0.19037,NO,74,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.296,-4.023,2.727,,,H,A,0.55,-0.91,0.746,,50,HHO,-1.34933,0.361275,0.00493255,0.19037 beta-lactamase_2500_L167Q,beta-lactamase_2500_167,TEM-1,beta-lactamase_2500,P62593,0.190415,NO,167,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.138,-4.038,2.9,,0.015,G,A,0.55,-0.63,7.813,,64.69,AHP,-1.30767,0.361275,0.00303566,0.190415 kka2_1:1_F264E,kka2_1:1_264,Kka2,kka2_1:1,P00552,0.19042,NO,264,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.02,-3.943,2.923,,0.296,.,?,0.58,0.02,2.303,,71.59,HHNA,-0.9655,0.520039,,0.19042 kka2_1:1_A41F,kka2_1:1_41,Kka2,kka2_1:1,P00552,0.190499,NO,41,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.879,-3.42,1.541,,0.184,.,B,0.46,-0.96,18.207,18.207,64.39,PHP,-2.477,0.520039,0.00543332,0.190499 kka2_1:1_D183H,kka2_1:1_183,Kka2,kka2_1:1,P00552,0.190549,NO,183,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.204,-4.489,3.285,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.520039,0.00426304,0.190549 kka2_1:2_A224H,kka2_1:2_224,Kka2,kka2_1:2,P00552,0.190565,NO,224,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.977,-4.809,3.832,,,H,A,0.46,-1.26,1.646,,63.64,HHP,-1.41033,0.295029,0.00352047,0.190565 beta-lactamase_2500_D83L,beta-lactamase_2500_83,TEM-1,beta-lactamase_2500,P62593,0.190615,NO,83,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.066,-3.79,2.724,,0.354,H,A,0.75,0.22,0.239,,48.95,HAH,-1.34733,0.361275,0.00205968,0.190615 beta-lactamase_156_Y44S,beta-lactamase_156_44,TEM-1,beta-lactamase_156,P62593,0.190661,NO,44,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-2.547,-3.605,1.058,,,E,B,0.21,-0.45,2.184,,73.78,OHH,-1.86267,0.111618,0.00426364,0.190661 kka2_1:1_G245D,kka2_1:1_245,Kka2,kka2_1:1,P00552,0.190672,NO,245,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.812,-3.456,2.644,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.520039,0.00683899,0.190672 beta-lactamase_2500_G43D,beta-lactamase_2500_43,TEM-1,beta-lactamase_2500,P62593,0.190702,NO,43,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.62,-3.469,2.849,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.361275,0.00120151,0.190702 Pab1_I130D,Pab1_130,Pab1,Pab1,P04147,0.190743,NO,130,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.212,-3.736,2.524,,,E,B,1.23,0.01,,,,HHB,-1.188,0.175299,0.000351112,0.190743 kka2_1:1_D216W,kka2_1:1_216,Kka2,kka2_1:1,P00552,0.190793,NO,216,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.785,-5.543,4.758,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.520039,0.00229969,0.190793 kka2_1:1_A144L,kka2_1:1_144,Kka2,kka2_1:1,P00552,0.190806,NO,144,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.859,-3.107,2.248,,,H,A,0.46,0.21,0.842,,52.65,BHB,-1.72933,0.520039,0.00231095,0.190806 kka2_1:2_D261I,kka2_1:2_261,Kka2,kka2_1:2,P00552,0.190863,NO,261,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.708,-4.039,3.331,,0.146,G,A,0.75,-0.33,,,,HAA,-0.759333,0.295029,0.0224846,0.190863 E1_Ubiquitin_G75P,E1_Ubiquitin_75,Uba1,E1_Ubiquitin,P0CG63,0.190981,NO,75,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.999,-3.75,2.751,,0.552,T,A,0.75,0.9,4.369,,83.73,BOO,-1.1,0.18783,0.00153276,0.190981 kka2_1:8_V80E,kka2_1:8_80,Kka2,kka2_1:8,P00552,0.191157,NO,80,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.144,-3.785,2.641,,0.358,E,B,1.48,-0.24,2.562,,63.64,HHH,-1.64633,0.100394,0.00488211,0.191157 kka2_1:8_V80E,kka2_1:8_80,Kka2,kka2_1:8,P00552,0.191157,NO,80,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.144,-3.785,2.641,,0.358,E,B,1.48,-0.24,2.562,,63.64,HHH,-1.64633,0.100394,0.00488211,0.191157 beta-lactamase_625_G243R,beta-lactamase_625_243,TEM-1,beta-lactamase_625,P62593,0.191234,NO,243,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.213352,0.00464034,0.191234 beta-lactamase_2500_L120K,beta-lactamase_2500_120,TEM-1,beta-lactamase_2500,P62593,0.191241,NO,120,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.044,-3.668,2.624,,,H,A,0.55,-1.13,2.48,,64.69,AHO,-1.13633,0.361275,0.00143563,0.191241 kka2_1:2_D220M,kka2_1:2_220,Kka2,kka2_1:2,P00552,0.191242,NO,220,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.787,-4.844,4.057,,,H,A,0.75,-1.14,0.745,,46.59,PAH,-1.152,0.295029,0.00158066,0.191242 beta-lactamase_2500_I280P,beta-lactamase_2500_280,TEM-1,beta-lactamase_2500,P62593,0.191265,NO,280,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.361275,0.0530888,0.191265 kka2_1:1_W24D,kka2_1:1_24,Kka2,kka2_1:1,P00552,0.191276,NO,24,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-1.779,-4.166,2.387,,0.477,E,B,0.47,-0.21,2.375,,56.06,AHH,-2.24467,0.520039,0.00631564,0.191276 kka2_1:4_P194I,kka2_1:4_194,Kka2,kka2_1:4,P00552,0.191305,NO,194,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.846,-4.06,3.214,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.168804,0.00314194,0.191305 kka2_1:2_F48W,kka2_1:2_48,Kka2,kka2_1:2,P00552,0.191306,NO,48,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.453,-4.763,3.31,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.295029,0.00475422,0.191306 beta-lactamase_625_S104E,beta-lactamase_625_104,TEM-1,beta-lactamase_625,P62593,0.191336,NO,104,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.015,-3.366,2.351,,0.04,,b,0.27,0.57,1.76,,63.29,HPO,-1.05267,0.213352,0.00218083,0.191336 beta-lactamase_K32P,beta-lactamase_32,TEM-1,beta-lactamase,P62593,0.191344,NO,32,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.984,-3.947,1.963,5.55842,0.563,H,A,1.82,0.34,1.754,,73.08,HBA,-2.04233,0.221079,0.00401283,0.191344 beta-lactamase_2500_I277S,beta-lactamase_2500_277,TEM-1,beta-lactamase_2500,P62593,0.19136,NO,277,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.361275,0.0169305,0.19136 beta-lactamase_39_I244K,beta-lactamase_39_244,TEM-1,beta-lactamase_39,P62593,0.19137,NO,244,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.555,-3.812,2.257,,,E,B,0.48,-0.84,1.325,,77.62,OHH,-1.385,0.0495842,0.00605379,0.19137 PSD95pdz3_I359E,PSD95pdz3_359,PSD95pdz3,PSD95pdz3,P31016,0.191374,NO,359,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.63,-3.572,1.942,5.35151,,,,,14.8012,,,,PHH,-1.58667,0.0758425,0.000580694,0.191374 kka2_1:2_A224D,kka2_1:2_224,Kka2,kka2_1:2,P00552,0.191376,NO,224,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.977,-3.763,2.786,,,H,A,0.46,-1.26,1.646,,63.64,HHP,-1.41033,0.295029,0.00352047,0.191376 kka2_1:2_A224Q,kka2_1:2_224,Kka2,kka2_1:2,P00552,0.191391,NO,224,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.977,-4.028,3.051,,,H,A,0.46,-1.26,1.646,,63.64,HHP,-1.41033,0.295029,0.00352047,0.191391 beta-lactamase_625_D177P,beta-lactamase_625_177,TEM-1,beta-lactamase_625,P62593,0.191436,NO,177,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.967,-3.764,2.797,,0.006,T,L,0.75,-1.02,1.333,,64.69,BAP,-0.873667,0.213352,0.000864022,0.191436 PSD95pdz3_I359Q,PSD95pdz3_359,PSD95pdz3,PSD95pdz3,P31016,0.191436,NO,359,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.63,-4.031,2.401,5.35151,,,,,14.8012,,,,PHH,-1.58667,0.0758425,0.000580694,0.191436 beta-lactamase_156_P181N,beta-lactamase_156_181,TEM-1,beta-lactamase_156,P62593,0.19146,NO,181,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.813,-3.924,3.111,,,H,A,0.52,-1.14,1.078,,61.54,HOH,-1.795,0.111618,0.000703122,0.19146 kka2_1:1_Y22P,kka2_1:1_22,Kka2,kka2_1:1,P00552,0.191469,NO,22,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-1.583,-4.113,2.53,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.520039,0.00598977,0.191469 beta-lactamase_625_V259K,beta-lactamase_625_259,TEM-1,beta-lactamase_625,P62593,0.191484,NO,259,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.213352,0.0070773,0.191484 kka2_1:2_Q219W,kka2_1:2_219,Kka2,kka2_1:2,P00552,0.191493,NO,219,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-0.93,-5.169,4.239,,0.088,H,A,0.4,-0.85,1.917,,50,HPA,-1.05167,0.295029,0.00237913,0.191493 kka2_1:2_G245W,kka2_1:2_245,Kka2,kka2_1:2,P00552,0.191534,NO,245,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.812,-5.257,4.445,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.295029,0.00683899,0.191534 beta-lactamase_625_A132P,beta-lactamase_625_132,TEM-1,beta-lactamase_625,P62593,0.191542,NO,132,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.9,-3.725,2.825,,,H,A,0.46,-0.93,0.316,,64.69,PHH,-1.138,0.213352,0.000962524,0.191542 kka2_1:8_M116P,kka2_1:8_116,Kka2,kka2_1:8,P00552,0.191542,NO,116,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-2.482,-4.193,1.711,,,H,A,1.59,-0.88,4.659,,71.59,HHH,-1.63867,0.100394,0.00745147,0.191542 kka2_1:8_M116P,kka2_1:8_116,Kka2,kka2_1:8,P00552,0.191542,NO,116,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-2.482,-4.193,1.711,,,H,A,1.59,-0.88,4.659,,71.59,HHH,-1.63867,0.100394,0.00745147,0.191542 kka2_1:1_L193W,kka2_1:1_193,Kka2,kka2_1:1,P00552,0.191568,NO,193,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.983,-5.198,4.215,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.520039,0.00480179,0.191568 beta-lactamase_2500_A235F,beta-lactamase_2500_235,TEM-1,beta-lactamase_2500,P62593,0.191604,NO,235,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.266,-4.199,2.933,,0.32,E,B,0.46,-0.86,0.891,,50,OHO,-0.89,0.361275,0.00493474,0.191604 kka2_1:1_Y244Q,kka2_1:1_244,Kka2,kka2_1:1,P00552,0.191633,NO,244,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-0.775,-3.928,3.153,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.520039,0.00453187,0.191633 kka2_1:2_V214F,kka2_1:2_214,Kka2,kka2_1:2,P00552,0.191649,NO,214,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.261,-3.945,2.684,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.295029,0.00692782,0.191649 beta-lactamase_625_S128P,beta-lactamase_625_128,TEM-1,beta-lactamase_625,P62593,0.191652,NO,128,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-0.84,-3.655,2.815,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.213352,0.00071483,0.191652 beta-lactamase_Y44E,beta-lactamase_44,TEM-1,beta-lactamase,P62593,0.191658,NO,44,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-2.547,-3.866,1.319,5.6273,,E,B,2.55,-0.45,2.683,,73.78,OHH,-1.86267,0.221079,0.00426364,0.191658 kka2_1:2_L241I,kka2_1:2_241,Kka2,kka2_1:2,P00552,0.191705,NO,241,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.158,-3.164,2.006,,0.08,H,A,0.55,-0.82,1.598,,63.26,HHH,-1.58533,0.295029,0.0117299,0.191705 kka2_1:4_F206T,kka2_1:4_206,Kka2,kka2_1:4,P00552,0.191725,NO,206,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.349,-3.71,2.361,,0.006,E,B,0.58,-1.21,1.342,,63.64,OHH,-1.04,0.168804,0.00936868,0.191725 beta-lactamase_2500_N134A,beta-lactamase_2500_134,TEM-1,beta-lactamase_2500,P62593,0.191776,NO,134,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-0.879,-3.3,2.421,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.361275,0.000644786,0.191776 kka2_1:1_I228K,kka2_1:1_228,Kka2,kka2_1:1,P00552,0.191777,NO,228,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.142,-3.919,2.777,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.520039,0.00458834,0.191777 kka2_1:1_E111A,kka2_1:1_111,Kka2,kka2_1:1,P00552,0.191779,NO,111,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.28,-2.356,0.076,,0.155,H,A,1.52,-1.14,15.716,15.716,65.53,HAB,-2.27833,0.520039,0.00746789,0.191779 kka2_1:4_G210K,kka2_1:4_210,Kka2,kka2_1:4,P00552,0.191858,NO,210,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.095,-3.696,2.601,,0.103,T,A,0.29,-0.62,0.271,,50,OOB,-0.966667,0.168804,0.00598378,0.191858 kka2_1:8_F240W,kka2_1:8_240,Kka2,kka2_1:8,P00552,0.191928,NO,240,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-0.911,-4.558,3.647,,,H,A,1.62,-1.21,0.697,,50.38,BHH,-1.67267,0.100394,0.00552543,0.191928 kka2_1:8_F240W,kka2_1:8_240,Kka2,kka2_1:8,P00552,0.191928,NO,240,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-0.911,-4.558,3.647,,,H,A,1.62,-1.21,0.697,,50.38,BHH,-1.67267,0.100394,0.00552543,0.191928 WW_domain_F189V,WW_domain_189,Yap65,WW_domain,P46937,0.191965,NO,189,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.632,-3.133,1.501,5.47284,,,,,,6.165,,56.94,HHH,-1.454,0.153962,0.00308453,0.191965 beta-lactamase_2500_W227M,beta-lactamase_2500_227,TEM-1,beta-lactamase_2500,P62593,0.191972,NO,227,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-0.982,-4.54,3.558,,0.272,,B,0.47,-0.29,1.37,,74.48,OHH,-1.595,0.361275,0.00226019,0.191972 kka2_1:2_F203G,kka2_1:2_203,Kka2,kka2_1:2,P00552,0.192043,NO,203,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-0.911,-3.675,2.764,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.295029,0.00318738,0.192043 kka2_1:8_D159K,kka2_1:8_159,Kka2,kka2_1:8,P00552,0.19212,NO,159,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.82,-3.549,2.729,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.100394,0.0030485,0.19212 kka2_1:8_D159K,kka2_1:8_159,Kka2,kka2_1:8,P00552,0.19212,NO,159,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.82,-3.549,2.729,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.100394,0.0030485,0.19212 kka2_1:8_G189H,kka2_1:8_189,Kka2,kka2_1:8,P00552,0.19212,NO,189,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.596,-4.708,4.112,,0.034,S,l,0.75,-0.99,,,,BOA,-0.739,0.100394,0.00253688,0.19212 kka2_1:8_G189H,kka2_1:8_189,Kka2,kka2_1:8,P00552,0.19212,NO,189,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.596,-4.708,4.112,,0.034,S,l,0.75,-0.99,,,,BOA,-0.739,0.100394,0.00253688,0.19212 kka2_1:2_A237W,kka2_1:2_237,Kka2,kka2_1:2,P00552,0.192132,NO,237,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.12,-5.457,3.337,,0.068,H,A,0.46,-0.71,2.369,,92.05,HHA,-2.10433,0.295029,0.012257,0.192132 kka2_1:1_I207K,kka2_1:1_207,Kka2,kka2_1:1,P00552,0.192136,NO,207,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.175,-3.925,2.75,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.520039,0.00611824,0.192136 beta-lactamase_Y95R,beta-lactamase_95,TEM-1,beta-lactamase,P62593,0.192145,NO,95,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-1.715,-4.186,2.471,5.67068,0.122,,b,0.96,-0.37,2.341,,77.62,BHP,-2.16167,0.221079,0.00479449,0.192145 kka2_1:2_G210H,kka2_1:2_210,Kka2,kka2_1:2,P00552,0.192181,NO,210,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.095,-4.794,3.699,,0.103,T,A,0.29,-0.62,0.271,,50,OOB,-0.966667,0.295029,0.00598378,0.192181 kka2_1:2_I196G,kka2_1:2_196,Kka2,kka2_1:2,P00552,0.192223,NO,196,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-2.115,-3.858,1.743,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.295029,0.0107273,0.192223 beta-lactamase_625_V260Q,beta-lactamase_625_260,TEM-1,beta-lactamase_625,P62593,0.192261,NO,260,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.213352,0.00471757,0.192261 kka2_1:4_R38W,kka2_1:4_38,Kka2,kka2_1:4,P00552,0.192276,NO,38,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.207,-5.334,4.127,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.168804,0.00372499,0.192276 kka2_1:4_D208C,kka2_1:4_208,Kka2,kka2_1:4,P00552,0.19231,NO,208,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.708,-5.115,4.407,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.168804,0.00212588,0.19231 kka2_1:2_E161Y,kka2_1:2_161,Kka2,kka2_1:2,P00552,0.192345,NO,161,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.581,-4.394,2.813,,0.829,G,A,1.52,2.24,1.612,,92.05,AAB,-1.861,0.295029,0.00760103,0.192345 beta-lactamase_625_D161P,beta-lactamase_625_161,TEM-1,beta-lactamase_625,P62593,0.192409,NO,161,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.891,-3.704,2.813,,0.341,,A,0.75,-0.52,4.655,,61.19,HAB,-0.961333,0.213352,0.000897697,0.192409 beta-lactamase_2500_L205H,beta-lactamase_2500_205,TEM-1,beta-lactamase_2500,P62593,0.19243,NO,205,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.922,-4.828,3.906,,,H,A,0.55,-0.46,0.831,,42.31,PHH,-1.57767,0.361275,0.00255802,0.19243 PSD95pdz3_H372P,PSD95pdz3_372,PSD95pdz3,PSD95pdz3,P31016,0.192434,NO,372,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-1.627,-3.561,1.934,5.5607,,,,,17.008,,,,PBA,-1.63033,0.0758425,0.00040301,0.192434 kka2_1:1_L223Q,kka2_1:1_223,Kka2,kka2_1:1,P00552,0.192449,NO,223,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.861,-4.235,3.374,,,H,A,0.55,-1.24,1.268,,50,HHH,-0.854333,0.520039,0.00253574,0.192449 beta-lactamase_39_A124R,beta-lactamase_39_124,TEM-1,beta-lactamase_39,P62593,0.19246,NO,124,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.181,-3.827,2.646,,,H,A,0.46,-0.9,1.367,,64.34,HHH,-1.152,0.0495842,0.00481399,0.19246 kka2_1:1_L92Y,kka2_1:1_92,Kka2,kka2_1:1,P00552,0.192472,NO,92,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.893,-4.021,3.128,,0.007,E,B,0.55,-0.19,1.447,,63.26,HHH,-0.962,0.520039,0.00307177,0.192472 kka2_1:1_G95F,kka2_1:1_95,Kka2,kka2_1:1,P00552,0.192592,NO,95,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-2.403,-4.378,1.975,,0.126,E,B,0.29,-0.74,7.822,,71.59,HOA,-2.198,0.520039,0.00743616,0.192592 kka2_1:2_L67D,kka2_1:2_67,Kka2,kka2_1:2,P00552,0.19261,NO,67,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.741,-4.172,3.431,,0.007,H,A,1.59,-0.66,,,,BHP,-1.42867,0.295029,0.00102787,0.19261 kka2_1:1_L158I,kka2_1:1_158,Kka2,kka2_1:1,P00552,0.192631,NO,158,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.947,-3.293,1.346,,0.095,.,B,0.55,0.77,7.588,,63.64,AHA,-1.25333,0.520039,0.00529068,0.192631 beta-lactamase_39_V42P,beta-lactamase_39_42,TEM-1,beta-lactamase_39,P62593,0.192731,NO,42,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.564,-4.095,2.531,,0.017,E,B,0.44,-0.51,1.86,,63.99,BHO,-1.042,0.0495842,0.00404515,0.192731 kka2_1:2_M116G,kka2_1:2_116,Kka2,kka2_1:2,P00552,0.19277,NO,116,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-2.482,-3.754,1.272,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.295029,0.00745147,0.19277 beta-lactamase_2500_L219C,beta-lactamase_2500_219,TEM-1,beta-lactamase_2500,P62593,0.192809,NO,219,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.313,-3.103,1.79,,,I,A,0.55,-0.51,35.994,35.994,74.48,HHB,-1.21533,0.361275,0.00664345,0.192809 beta-lactamase_39_A132F,beta-lactamase_39_132,TEM-1,beta-lactamase_39,P62593,0.192832,NO,132,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.9,-4.091,3.191,,,H,A,0.46,-0.93,8.408,,64.69,PHH,-1.138,0.0495842,0.000962524,0.192832 kka2_1:2_A222W,kka2_1:2_222,Kka2,kka2_1:2,P00552,0.192843,NO,222,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.725,-5.351,4.626,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.295029,0.00207657,0.192843 kka2_1:4_P194K,kka2_1:4_194,Kka2,kka2_1:4,P00552,0.192862,NO,194,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.846,-3.507,2.661,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.168804,0.00314194,0.192862 kka2_1:4_Y244F,kka2_1:4_244,Kka2,kka2_1:4,P00552,0.192875,NO,244,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-0.775,-2.97,2.195,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.168804,0.00453187,0.192875 beta-lactamase_625_G43E,beta-lactamase_625_43,TEM-1,beta-lactamase_625,P62593,0.192901,NO,43,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.62,-3.665,3.045,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.213352,0.00120151,0.192901 beta-lactamase_2500_L205D,beta-lactamase_2500_205,TEM-1,beta-lactamase_2500,P62593,0.192944,NO,205,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.922,-4.118,3.196,,,H,A,0.55,-0.46,0.831,,42.31,PHH,-1.57767,0.361275,0.00255802,0.192944 beta-lactamase_2500_G281R,beta-lactamase_2500_281,TEM-1,beta-lactamase_2500,P62593,0.192964,NO,281,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.361275,0.0406482,0.192964 kka2_1:2_V214S,kka2_1:2_214,Kka2,kka2_1:2,P00552,0.193018,NO,214,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.261,-3.744,2.483,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.295029,0.00692782,0.193018 beta-lactamase_G248Q,beta-lactamase_248,TEM-1,beta-lactamase,P62593,0.193019,NO,248,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.794,-2.807,1.013,4.69798,,E,b,0.23,-0.43,1.782,,61.19,HOO,-1.52867,0.221079,0.00428493,0.193019 kka2_1:1_G205T,kka2_1:1_205,Kka2,kka2_1:1,P00552,0.193028,NO,205,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.596,-3.675,3.079,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.520039,0.00221855,0.193028 kka2_1:1_A64Y,kka2_1:1_64,Kka2,kka2_1:1,P00552,0.193041,NO,64,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.496,-4.253,2.757,,0.039,H,A,0.46,-0.57,1.175,,56.06,AHH,-1.334,0.520039,0.00705578,0.193041 beta-lactamase_625_Y262G,beta-lactamase_625_262,TEM-1,beta-lactamase_625,P62593,0.193061,NO,262,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.213352,0.00853516,0.193061 kka2_1:8_R258F,kka2_1:8_258,Kka2,kka2_1:8,P00552,0.193081,NO,258,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.626,-4.327,2.701,,0.316,H,A,0.16,-0.85,5.58,,53.03,HBH,-1.25933,0.100394,0.00983174,0.193081 kka2_1:8_R258F,kka2_1:8_258,Kka2,kka2_1:8,P00552,0.193081,NO,258,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.626,-4.327,2.701,,0.316,H,A,0.16,-0.85,5.58,,53.03,HBH,-1.25933,0.100394,0.00983174,0.193081 kka2_1:1_L184H,kka2_1:1_184,Kka2,kka2_1:1,P00552,0.193136,NO,184,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.496,-4.936,3.44,,0.489,E,B,0.55,-0.06,19.127,19.127,63.26,AHH,-1.24833,0.520039,0.00518742,0.193136 beta-lactamase_2500_V42N,beta-lactamase_2500_42,TEM-1,beta-lactamase_2500,P62593,0.193286,NO,42,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.564,-4.165,2.601,,0.017,E,B,0.44,-0.51,1.86,,63.99,BHO,-1.042,0.361275,0.00404515,0.193286 beta-lactamase_2500_D174Y,beta-lactamase_2500_174,TEM-1,beta-lactamase_2500,P62593,0.193358,NO,174,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.738,-4.387,3.649,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.361275,0.00125633,0.193358 beta-lactamase_2500_V31S,beta-lactamase_2500_31,TEM-1,beta-lactamase_2500,P62593,0.193446,NO,31,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.822,-3.594,1.772,,,H,A,0.44,-0.46,0.955,,73.78,BHB,-2.03767,0.361275,0.00478065,0.193446 kka2_1:2_P194E,kka2_1:2_194,Kka2,kka2_1:2,P00552,0.193474,NO,194,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.846,-3.407,2.561,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.295029,0.00314194,0.193474 beta-lactamase_625_L191P,beta-lactamase_625_191,TEM-1,beta-lactamase_625,P62593,0.193475,NO,191,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.087,-4.09,3.003,,,H,A,0.55,0.09,1.908,,63.29,BHH,-1.445,0.213352,0.00263549,0.193475 kka2_1:1_N195P,kka2_1:1_195,Kka2,kka2_1:1,P00552,0.193536,NO,195,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-0.836,-3.906,3.07,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.520039,0.00276134,0.193536 kka2_1:4_R226E,kka2_1:4_226,Kka2,kka2_1:4,P00552,0.193541,NO,226,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.392,-3.484,2.092,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.168804,0.0108032,0.193541 kka2_1:1_E63H,kka2_1:1_63,Kka2,kka2_1:1,P00552,0.193542,NO,63,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-0.762,-4.258,3.496,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.520039,0.00118399,0.193542 beta-lactamase_L137D,beta-lactamase_137,TEM-1,beta-lactamase,P62593,0.193543,NO,137,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.03,-4.128,3.098,5.20117,,H,A,1.07,-0.38,0.674,,42.31,HHP,-1.58933,0.221079,0.00278599,0.193543 Ubiquitin_G75E,Ubiquitin_75,Uba1,Ubiquitin,P0CG48,0.193548,NO,75,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.613,-2.905,1.292,5.44099,0.552,T,A,0.73,0.9,4.017,,34.31,BOO,-1.66767,0.205827,0.000712673,0.193548 Ubiquitin_I3E,Ubiquitin_3,Uba1,Ubiquitin,P0CG48,0.193548,NO,3,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.402,-3.83,2.428,4.80819,,E,B,,-0.78,,,,PHH,-1.54533,0.205827,0.000836911,0.193548 Ubiquitin_V70S,Ubiquitin_70,Uba1,Ubiquitin,P0CG48,0.193548,NO,70,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.874,-3.522,1.648,5.29728,0.05,E,B,0.96,-0.97,2.363,,34.31,HHH,-1.65533,0.205827,0.00106871,0.193548 kka2_1:1_C192K,kka2_1:1_192,Kka2,kka2_1:1,P00552,0.193556,NO,192,C,K,CK,Special,PositiveCharge,5.07,9.74,4.67,202,121,146,25,108.5,168.6,60.1,-1.067,-3.841,2.774,,0.095,.,B,0.46,-0.75,2.749,,50,HOH,-0.960333,0.520039,0.00485428,0.193556 beta-lactamase_2500_H287P,beta-lactamase_2500_287,TEM-1,beta-lactamase_2500,P62593,0.193562,NO,287,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,,,,,,,,,,,,,BBH,-1.111,0.361275,,0.193562 beta-lactamase_156_I245R,beta-lactamase_156_245,TEM-1,beta-lactamase_156,P62593,0.193611,NO,245,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.111618,0.00391032,0.193611 beta-lactamase_2500_Y262S,beta-lactamase_2500_262,TEM-1,beta-lactamase_2500,P62593,0.193649,NO,262,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.361275,0.00853516,0.193649 beta-lactamase_39_L120P,beta-lactamase_39_120,TEM-1,beta-lactamase_39,P62593,0.193655,NO,120,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.044,-4.17,3.126,,,H,A,0.55,-1.13,22.254,22.254,64.69,AHO,-1.13633,0.0495842,0.00143563,0.193655 beta-lactamase_2500_I280C,beta-lactamase_2500_280,TEM-1,beta-lactamase_2500,P62593,0.193698,NO,280,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.361275,0.0530888,0.193698 beta-lactamase_156_T158E,beta-lactamase_156_158,TEM-1,beta-lactamase_156,P62593,0.193713,NO,158,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.116,-3.449,2.333,,0.036,,B,0.22,-0.85,3.771,,69.58,HPB,-1.269,0.111618,0.00341825,0.193713 beta-lactamase_625_G43T,beta-lactamase_625_43,TEM-1,beta-lactamase_625,P62593,0.193714,NO,43,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.62,-3.646,3.026,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.213352,0.00120151,0.193714 kka2_1:1_L260W,kka2_1:1_260,Kka2,kka2_1:1,P00552,0.193724,NO,260,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.741,-5.126,4.385,,0.022,H,A,0.55,-0.52,,,,HHA,-0.845667,0.520039,0.0233782,0.193724 beta-lactamase_156_D129T,beta-lactamase_156_129,TEM-1,beta-lactamase_156,P62593,0.193753,NO,129,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.816,-3.447,2.631,,,,B,0.75,-0.69,1.924,,34.97,PAP,-0.818,0.111618,0.00109178,0.193753 beta-lactamase_156_T69D,beta-lactamase_156_69,TEM-1,beta-lactamase_156,P62593,0.193761,NO,69,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-0.973,-3.534,2.561,,,G,A,0.22,-1.24,4.194,,93.01,PPH,-1.01833,0.111618,0.00127498,0.193761 kka2_1:1_G74P,kka2_1:1_74,Kka2,kka2_1:1,P00552,0.193783,NO,74,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.18,-3.953,2.773,,0.621,T,l,0.75,0.2,15.356,15.356,64.39,POH,-1.91667,0.520039,0.00587035,0.193783 kka2_1:4_R217N,kka2_1:4_217,Kka2,kka2_1:4,P00552,0.193829,NO,217,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.158,-3.736,2.578,,0.252,T,A,1.2,-0.59,2.074,,52.27,ABH,-1.127,0.168804,0.0047191,0.193829 beta-lactamase_A245Y,beta-lactamase_245,TEM-1,beta-lactamase,P62593,0.193917,NO,245,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.068,-4.251,3.183,4.78972,,E,B,0.17,-0.92,0.831,,64.69,HHH,-1.58133,0.221079,0.00391032,0.193917 beta-lactamase_M67R,beta-lactamase_67,TEM-1,beta-lactamase,P62593,0.193994,NO,67,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-2.231,-3.989,1.758,4.9618,0.006,G,P,1.07,-0.81,1.463,,65.03,HHP,-1.502,0.221079,0.00409753,0.193994 beta-lactamase_625_S68Y,beta-lactamase_625_68,TEM-1,beta-lactamase_625,P62593,0.194019,NO,68,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-0.913,-4.188,3.275,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.213352,0.000800065,0.194019 kka2_1:4_L260A,kka2_1:4_260,Kka2,kka2_1:4,P00552,0.194021,NO,260,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.741,-3.106,2.365,,0.022,H,A,0.55,-0.52,,,,HHA,-0.845667,0.168804,0.0233782,0.194021 beta-lactamase_625_Y262R,beta-lactamase_625_262,TEM-1,beta-lactamase_625,P62593,0.194028,NO,262,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.213352,0.00853516,0.194028 beta-lactamase_2500_H287I,beta-lactamase_2500_287,TEM-1,beta-lactamase_2500,P62593,0.194081,NO,287,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,,,,,,,,,,,,,BBH,-1.111,0.361275,,0.194081 beta-lactamase_625_I277S,beta-lactamase_625_277,TEM-1,beta-lactamase_625,P62593,0.194094,NO,277,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.213352,0.0169305,0.194094 kka2_1:1_E96I,kka2_1:1_96,Kka2,kka2_1:1,P00552,0.194104,NO,96,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.573,-3.722,1.149,,0.476,,B,1.52,-0.65,1.254,,71.59,OAH,-2.143,0.520039,0.00369441,0.194104 beta-lactamase_625_V72H,beta-lactamase_625_72,TEM-1,beta-lactamase_625,P62593,0.194135,NO,72,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.658,-4.908,3.25,,,H,A,0.44,-1.03,0.981,,65.73,BHH,-1.32167,0.213352,0.00501194,0.194135 beta-lactamase_625_D155P,beta-lactamase_625_155,TEM-1,beta-lactamase_625,P62593,0.194194,NO,155,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.889,-3.725,2.836,,0.049,,B,0.75,-0.9,4.922,,64.69,OAB,-1.62267,0.213352,0.00135315,0.194194 kka2_1:4_K112W,kka2_1:4_112,Kka2,kka2_1:4,P00552,0.194226,NO,112,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-2.491,-5.516,3.025,,0.076,H,A,2.34,-1.37,0.39,,56.06,ABH,-2.00133,0.168804,0.00645389,0.194226 kka2_1:8_D261C,kka2_1:8_261,Kka2,kka2_1:8,P00552,0.19423,NO,261,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.708,-5.115,4.407,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.100394,0.0224846,0.19423 kka2_1:8_D261C,kka2_1:8_261,Kka2,kka2_1:8,P00552,0.19423,NO,261,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.708,-5.115,4.407,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.100394,0.0224846,0.19423 PSD95pdz3_H372K,PSD95pdz3_372,PSD95pdz3,PSD95pdz3,P31016,0.194241,NO,372,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-1.627,-3.139,1.512,5.5607,,,,,17.008,,,,PBA,-1.63033,0.0758425,0.00040301,0.194241 kka2_1:1_V198K,kka2_1:1_198,Kka2,kka2_1:1,P00552,0.194278,NO,198,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.719,-3.652,1.933,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.520039,0.00835002,0.194278 beta-lactamase_M127P,beta-lactamase_127,TEM-1,beta-lactamase,P62593,0.194293,NO,127,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-2.251,-4.144,1.893,5.40552,0.312,S,A,1.07,0.32,1.671,,72.73,PHP,-1.40433,0.221079,0.00437927,0.194293 beta-lactamase_625_I258Q,beta-lactamase_625_258,TEM-1,beta-lactamase_625,P62593,0.194308,NO,258,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.213352,0.007931,0.194308 beta-lactamase_156_L79D,beta-lactamase_156_79,TEM-1,beta-lactamase_156,P62593,0.194324,NO,79,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.842,-4.141,3.299,,0.007,H,A,0.55,-0.16,1.831,,50.35,HHP,-1.44333,0.111618,0.000947397,0.194324 kka2_1:2_L70K,kka2_1:2_70,Kka2,kka2_1:2,P00552,0.194373,NO,70,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.017,-3.772,2.755,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.295029,0.00411884,0.194373 kka2_1:4_N195E,kka2_1:4_195,Kka2,kka2_1:4,P00552,0.194381,NO,195,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-0.836,-3.211,2.375,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.168804,0.00276134,0.194381 beta-lactamase_625_L160D,beta-lactamase_625_160,TEM-1,beta-lactamase_625,P62593,0.194386,NO,160,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.977,-4.122,3.145,,0.022,,B,0.55,-0.6,0.237,,44.41,BHA,-0.936,0.213352,0.00193775,0.194386 beta-lactamase_0_T126W,beta-lactamase_0_126,TEM-1,beta-lactamase_0,P62593,0.194388,NO,126,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.122,-5.243,4.121,,0.05,H,A,0.22,-0.05,0.705,,44.41,HPH,-1.60467,0.0500837,0.00244552,0.194388 beta-lactamase_156_D129P,beta-lactamase_156_129,TEM-1,beta-lactamase_156,P62593,0.194399,NO,129,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.816,-3.68,2.864,,,,B,0.75,-0.69,1.924,,34.97,PAP,-0.818,0.111618,0.00109178,0.194399 beta-lactamase_2500_A124E,beta-lactamase_2500_124,TEM-1,beta-lactamase_2500,P62593,0.194478,NO,124,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.181,-3.544,2.363,,,H,A,0.46,-0.9,0.314,,64.34,HHH,-1.152,0.361275,0.00481399,0.194478 kka2_1:2_R226Q,kka2_1:2_226,Kka2,kka2_1:2,P00552,0.194515,NO,226,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.392,-2.994,1.602,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.295029,0.0108032,0.194515 beta-lactamase_2500_I258S,beta-lactamase_2500_258,TEM-1,beta-lactamase_2500,P62593,0.194593,NO,258,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.361275,0.007931,0.194593 beta-lactamase_39_G43H,beta-lactamase_39_43,TEM-1,beta-lactamase_39,P62593,0.194601,NO,43,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.62,-4.68,4.06,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.0495842,0.00120151,0.194601 kka2_1:8_R253E,kka2_1:8_253,Kka2,kka2_1:8,P00552,0.194612,NO,253,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.356,-3.329,1.973,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.100394,0.0144195,0.194612 kka2_1:8_R253E,kka2_1:8_253,Kka2,kka2_1:8,P00552,0.194612,NO,253,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.356,-3.329,1.973,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.100394,0.0144195,0.194612 beta-lactamase_625_L137P,beta-lactamase_625_137,TEM-1,beta-lactamase_625,P62593,0.194648,NO,137,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.03,-4.134,3.104,,,H,A,0.55,-0.38,1.5,,42.31,HHP,-1.58933,0.213352,0.00278599,0.194648 beta-lactamase_A245W,beta-lactamase_245,TEM-1,beta-lactamase,P62593,0.194658,NO,245,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.068,-5.353,4.285,4.78972,,E,B,0.17,-0.92,0.831,,64.69,HHH,-1.58133,0.221079,0.00391032,0.194658 beta-lactamase_625_T107Q,beta-lactamase_625_107,TEM-1,beta-lactamase_625,P62593,0.194687,NO,107,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.117,-3.889,2.772,,,G,A,0.22,-0.06,3.676,,67.83,HPA,-1.265,0.213352,0.00239347,0.194687 kka2_1:4_A215W,kka2_1:4_215,Kka2,kka2_1:4,P00552,0.194729,NO,215,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.968,-5.417,4.449,,0.039,E,B,0.46,-0.59,0.754,,50.38,HHA,-1.00467,0.168804,0.00529129,0.194729 beta-lactamase_625_A246R,beta-lactamase_625_246,TEM-1,beta-lactamase_625,P62593,0.19475,NO,246,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.121,-4.154,2.033,,0.01,E,B,0.46,-1.01,1.201,,73.78,HHH,-1.55633,0.213352,0.00569458,0.19475 kka2_1:4_C209Y,kka2_1:4_209,Kka2,kka2_1:4,P00552,0.194778,NO,209,C,Y,CY,Special,Hydrophobic,5.07,5.66,0.59,194,121,181,60,108.5,193.6,85.1,-0.906,-4.189,3.283,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.168804,0.00260862,0.194778 beta-lactamase_2500_V42Q,beta-lactamase_2500_42,TEM-1,beta-lactamase_2500,P62593,0.194796,NO,42,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.564,-4.229,2.665,,0.017,E,B,0.44,-0.51,1.86,,63.99,BHO,-1.042,0.361275,0.00404515,0.194796 PSD95pdz3_G330I,PSD95pdz3_330,PSD95pdz3,PSD95pdz3,P31016,0.194802,NO,330,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.008,-3.917,2.909,4.68351,,,,,31.405,,,,OOA,-1.14,0.0758425,0.000962386,0.194802 beta-lactamase_625_I258R,beta-lactamase_625_258,TEM-1,beta-lactamase_625,P62593,0.19484,NO,258,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.213352,0.007931,0.19484 beta-lactamase_2500_W208Q,beta-lactamase_2500_208,TEM-1,beta-lactamase_2500,P62593,0.194923,NO,208,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-0.818,-4.124,3.306,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.361275,0.00126609,0.194923 kka2_1:1_L60K,kka2_1:1_60,Kka2,kka2_1:1,P00552,0.195019,NO,60,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.997,-3.814,2.817,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.520039,0.00262176,0.195019 kka2_1:1_L123W,kka2_1:1_123,Kka2,kka2_1:1,P00552,0.195052,NO,123,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.888,-5.165,4.277,,0.007,H,A,0.55,-0.4,1.447,,48.86,BHB,-1.301,0.520039,0.00325188,0.195052 kka2_1:2_M197A,kka2_1:2_197,Kka2,kka2_1:2,P00552,0.195078,NO,197,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.707,-3.22,1.513,,0.121,E,B,0.55,-1.19,2.097,,65.53,HHH,-1.847,0.295029,0.00921295,0.195078 beta-lactamase_625_T131I,beta-lactamase_625_131,TEM-1,beta-lactamase_625,P62593,0.195083,NO,131,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.328,-3.758,2.43,,,H,A,0.22,-0.69,2.031,,67.48,PPH,-1.00867,0.213352,0.00345886,0.195083 beta-lactamase_2500_K232V,beta-lactamase_2500_232,TEM-1,beta-lactamase_2500,P62593,0.19512,NO,232,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.012,-3.626,2.614,,,E,B,2.34,-1.1,3.048,,65.03,ABP,-1.238,0.361275,0.00313441,0.19512 kka2_1:8_R226W,kka2_1:8_226,Kka2,kka2_1:8,P00552,0.195185,NO,226,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.392,-2.291,0.899,,0.222,H,A,0.16,-0.71,3.818,,56.06,PBA,-1.84767,0.100394,0.0108032,0.195185 kka2_1:8_R226W,kka2_1:8_226,Kka2,kka2_1:8,P00552,0.195185,NO,226,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.392,-2.291,0.899,,0.222,H,A,0.16,-0.71,3.818,,56.06,PBA,-1.84767,0.100394,0.0108032,0.195185 beta-lactamase_625_L188D,beta-lactamase_625_188,TEM-1,beta-lactamase_625,P62593,0.195194,NO,188,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.166,-3.967,2.801,,,H,A,0.55,-0.3,2.982,,60.14,PHB,-1.47033,0.213352,0.00295687,0.195194 kka2_1:1_G95D,kka2_1:1_95,Kka2,kka2_1:1,P00552,0.195213,NO,95,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-2.403,-2.891,0.488,,0.126,E,B,0.29,-0.74,7.822,,71.59,HOA,-2.198,0.520039,0.00743616,0.195213 kka2_1:4_Y257P,kka2_1:4_257,Kka2,kka2_1:4,P00552,0.195218,NO,257,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-1.064,-4.26,3.196,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.168804,0.0148191,0.195218 kka2_1:4_G189I,kka2_1:4_189,Kka2,kka2_1:4,P00552,0.195259,NO,189,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.596,-4.264,3.668,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.168804,0.00253688,0.195259 kka2_1:1_C77I,kka2_1:1_77,Kka2,kka2_1:1,P00552,0.195289,NO,77,C,I,CI,Special,Hydrophobic,5.07,6.02,0.95,198,121,131,10,108.5,166.7,58.2,-1.477,-3.673,2.196,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.520039,0.00441216,0.195289 beta-lactamase_2500_I280D,beta-lactamase_2500_280,TEM-1,beta-lactamase_2500,P62593,0.195306,NO,280,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.361275,0.0530888,0.195306 beta-lactamase_156_S128C,beta-lactamase_156_128,TEM-1,beta-lactamase_156,P62593,0.195307,NO,128,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-0.84,-4.637,3.797,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.111618,0.00071483,0.195307 kka2_1:2_D90K,kka2_1:2_90,Kka2,kka2_1:2,P00552,0.195344,NO,90,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.459,-3.563,1.104,,0.104,E,B,0.75,0.73,6.085,,64.39,BAH,-1.72833,0.295029,0.00583842,0.195344 beta-lactamase_2500_D129I,beta-lactamase_2500_129,TEM-1,beta-lactamase_2500,P62593,0.195345,NO,129,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.816,-4.036,3.22,,,,B,0.75,-0.69,1.29,,34.97,PAP,-0.818,0.361275,0.00109178,0.195345 beta-lactamase_625_A132L,beta-lactamase_625_132,TEM-1,beta-lactamase_625,P62593,0.195353,NO,132,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.9,-3.146,2.246,,,H,A,0.46,-0.93,0.316,,64.69,PHH,-1.138,0.213352,0.000962524,0.195353 beta-lactamase_2500_N274P,beta-lactamase_2500_274,TEM-1,beta-lactamase_2500,P62593,0.195355,NO,274,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.361275,0.0110418,0.195355 kka2_1:2_A144Q,kka2_1:2_144,Kka2,kka2_1:2,P00552,0.195363,NO,144,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.859,-4.01,3.151,,,H,A,0.46,0.21,6.844,,52.65,BHB,-1.72933,0.295029,0.00231095,0.195363 kka2_1:8_F37D,kka2_1:8_37,Kka2,kka2_1:8,P00552,0.195375,NO,37,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.427,-4.022,2.595,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.100394,0.00586193,0.195375 kka2_1:8_F37D,kka2_1:8_37,Kka2,kka2_1:8,P00552,0.195375,NO,37,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.427,-4.022,2.595,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.100394,0.00586193,0.195375 beta-lactamase_2500_P143K,beta-lactamase_2500_143,TEM-1,beta-lactamase_2500,P62593,0.195424,NO,143,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.967,-3.581,2.614,,0.075,H,A,0.52,-0.37,0.479,,66.78,OOB,-1.354,0.361275,0.00114551,0.195424 beta-lactamase_2500_T158L,beta-lactamase_2500_158,TEM-1,beta-lactamase_2500,P62593,0.195523,NO,158,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.116,-3.303,2.187,,0.036,,B,0.22,-0.85,1.344,,69.58,HPB,-1.269,0.361275,0.00341825,0.195523 beta-lactamase_156_T179Q,beta-lactamase_156_179,TEM-1,beta-lactamase_156,P62593,0.195538,NO,179,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.085,-3.906,2.821,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.111618,0.00226045,0.195538 beta-lactamase_156_L248N,beta-lactamase_156_248,TEM-1,beta-lactamase_156,P62593,0.195574,NO,248,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.111618,0.00428493,0.195574 kka2_1:4_P45Y,kka2_1:4_45,Kka2,kka2_1:4,P00552,0.195617,NO,45,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.774,-4.485,2.711,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.168804,0.00590481,0.195617 beta-lactamase_2500_D155Y,beta-lactamase_2500_155,TEM-1,beta-lactamase_2500,P62593,0.195632,NO,155,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.889,-4.387,3.498,,0.049,,B,0.75,-0.9,2.386,,64.69,OAB,-1.62267,0.361275,0.00135315,0.195632 beta-lactamase_2500_T179Q,beta-lactamase_2500_179,TEM-1,beta-lactamase_2500,P62593,0.195688,NO,179,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.085,-3.906,2.821,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.361275,0.00226045,0.195688 beta-lactamase_2500_D174V,beta-lactamase_2500_174,TEM-1,beta-lactamase_2500,P62593,0.195745,NO,174,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.738,-3.754,3.016,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.361275,0.00125633,0.195745 beta-lactamase_156_C121H,beta-lactamase_156_121,TEM-1,beta-lactamase_156,P62593,0.195773,NO,121,C,H,CH,Special,PositiveCharge,5.07,7.59,2.52,174,121,155,34,108.5,153.2,44.7,-0.953,-4.827,3.874,,,H,A,0.46,-0.81,1.136,,63.29,HOP,-1.46767,0.111618,0.000744322,0.195773 beta-lactamase_625_S104L,beta-lactamase_625_104,TEM-1,beta-lactamase_625,P62593,0.195827,NO,104,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.015,-3.359,2.344,,0.04,,b,0.27,0.57,1.76,,63.29,HPO,-1.05267,0.213352,0.00218083,0.195827 beta-lactamase_625_G240Y,beta-lactamase_625_240,TEM-1,beta-lactamase_625,P62593,0.195928,NO,240,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.213352,0.00591201,0.195928 kka2_1:1_Q136M,kka2_1:1_136,Kka2,kka2_1:1,P00552,0.195969,NO,136,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-3.021,-4.715,1.694,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.520039,0.00624149,0.195969 beta-lactamase_2500_S233Y,beta-lactamase_2500_233,TEM-1,beta-lactamase_2500,P62593,0.195976,NO,233,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.886,-4.293,2.407,,0.016,E,B,0.27,-1.01,2.851,,77.62,BPO,-1.17267,0.361275,0.00311415,0.195976 PSD95pdz3_L379D,PSD95pdz3_379,PSD95pdz3,PSD95pdz3,P31016,0.195986,NO,379,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.347,-3.825,2.478,5.37777,,,,,16.8762,,,,HHB,-1.35667,0.0758425,0.00029733,0.195986 kka2_1:4_G30Q,kka2_1:4_30,Kka2,kka2_1:4,P00552,0.195987,NO,30,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.596,-4.153,3.557,,0.54,S,g,0.29,3.76,,,,HOO,-1.51133,0.168804,0.00159208,0.195987 kka2_1:1_V97K,kka2_1:1_97,Kka2,kka2_1:1,P00552,0.196,NO,97,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.453,-3.837,2.384,,0.083,,B,1.48,-0.83,13.576,13.576,53.03,AHO,-1.85067,0.520039,0.00737869,0.196 kka2_1:4_G205N,kka2_1:4_205,Kka2,kka2_1:4,P00552,0.196025,NO,205,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.596,-3.476,2.88,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.168804,0.00221855,0.196025 beta-lactamase_2500_L137H,beta-lactamase_2500_137,TEM-1,beta-lactamase_2500,P62593,0.196068,NO,137,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.03,-4.934,3.904,,,H,A,0.55,-0.38,0.769,,42.31,HHP,-1.58933,0.361275,0.00278599,0.196068 beta-lactamase_625_E61P,beta-lactamase_625_61,TEM-1,beta-lactamase_625,P62593,0.196088,NO,61,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.115,-3.861,1.746,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.213352,0.00440955,0.196088 kka2_1:8_E262H,kka2_1:8_262,Kka2,kka2_1:8,P00552,0.196137,NO,262,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-0.829,-4.282,3.453,,0.059,G,A,1.52,-0.18,0.837,,42.42,AAH,-0.816,0.100394,0.0191586,0.196137 kka2_1:8_E262H,kka2_1:8_262,Kka2,kka2_1:8,P00552,0.196137,NO,262,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-0.829,-4.282,3.453,,0.059,G,A,1.52,-0.18,0.837,,42.42,AAH,-0.816,0.100394,0.0191586,0.196137 kka2_1:1_F206W,kka2_1:1_206,Kka2,kka2_1:1,P00552,0.196167,NO,206,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.349,-4.609,3.26,,0.006,E,B,0.58,-1.21,0.978,,63.64,OHH,-1.04,0.520039,0.00936868,0.196167 kka2_1:2_L243F,kka2_1:2_243,Kka2,kka2_1:2,P00552,0.196169,NO,243,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-2.651,-4.372,1.721,,0.277,H,A,1.59,-0.67,13.165,13.165,92.05,HHH,-2.03767,0.295029,0.00884927,0.196169 kka2_1:2_Y244N,kka2_1:2_244,Kka2,kka2_1:2,P00552,0.196205,NO,244,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-0.775,-3.926,3.151,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.295029,0.00453187,0.196205 kka2_1:1_A191Y,kka2_1:1_191,Kka2,kka2_1:1,P00552,0.196247,NO,191,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.831,-4.254,3.423,,,.,b,0.46,-0.94,0.53,,50,AHO,-0.868667,0.520039,0.00338807,0.196247 beta-lactamase_2500_G234D,beta-lactamase_2500_234,TEM-1,beta-lactamase_2500,P62593,0.196302,NO,234,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.62,-3.469,2.849,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.361275,0.000889577,0.196302 kka2_1:1_Q4A,kka2_1:1_4,Kka2,kka2_1:1,P00552,0.196313,NO,4,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.361,-2.857,0.496,,,,,,,5.615,,71.59,APA,-1.95533,0.520039,0.00239179,0.196313 kka2_1:2_M116D,kka2_1:2_116,Kka2,kka2_1:2,P00552,0.196477,NO,116,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-2.482,-4.161,1.679,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.295029,0.00745147,0.196477 beta-lactamase_625_D155T,beta-lactamase_625_155,TEM-1,beta-lactamase_625,P62593,0.196517,NO,155,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.889,-3.445,2.556,,0.049,,B,0.75,-0.9,4.922,,64.69,OAB,-1.62267,0.213352,0.00135315,0.196517 beta-lactamase_625_L146P,beta-lactamase_625_146,TEM-1,beta-lactamase_625,P62593,0.196573,NO,146,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.462,-4.216,2.754,,0.007,H,A,0.55,-0.56,2.16,,64.69,AHP,-1.656,0.213352,0.00474542,0.196573 kka2_1:2_L94N,kka2_1:2_94,Kka2,kka2_1:2,P00552,0.196638,NO,94,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.618,-4.108,2.49,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.295029,0.00520888,0.196638 beta-lactamase_2500_A230Y,beta-lactamase_2500_230,TEM-1,beta-lactamase_2500,P62593,0.196682,NO,230,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.154,-4.312,3.158,,0.01,E,B,0.46,-1.17,1.171,,50,HHA,-1.079,0.361275,0.00516841,0.196682 kka2_1:4_D190T,kka2_1:4_190,Kka2,kka2_1:4,P00552,0.196685,NO,190,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.708,-3.45,2.742,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.168804,0.00247989,0.196685 kka2_1:8_E63H,kka2_1:8_63,Kka2,kka2_1:8,P00552,0.196707,NO,63,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-0.762,-4.258,3.496,,0.043,H,A,1.52,-0.43,,,,AAH,-1.283,0.100394,0.00118399,0.196707 kka2_1:8_E63H,kka2_1:8_63,Kka2,kka2_1:8,P00552,0.196707,NO,63,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-0.762,-4.258,3.496,,0.043,H,A,1.52,-0.43,,,,AAH,-1.283,0.100394,0.00118399,0.196707 kka2_1:4_W91M,kka2_1:4_91,Kka2,kka2_1:4,P00552,0.196721,NO,91,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-1.178,-4.551,3.373,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.168804,0.00358653,0.196721 kka2_1:4_A222W,kka2_1:4_222,Kka2,kka2_1:4,P00552,0.196776,NO,222,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.725,-5.351,4.626,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.168804,0.00207657,0.196776 beta-lactamase_625_K232E,beta-lactamase_625_232,TEM-1,beta-lactamase_625,P62593,0.19682,NO,232,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.012,-3.087,2.075,,,E,B,2.34,-1.1,1.992,,65.03,ABP,-1.238,0.213352,0.00313441,0.19682 kka2_1:4_P109I,kka2_1:4_109,Kka2,kka2_1:4,P00552,0.196825,NO,109,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.412,-3.963,2.551,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.168804,0.0070929,0.196825 kka2_1:4_Q219E,kka2_1:4_219,Kka2,kka2_1:4,P00552,0.196825,NO,219,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-0.93,-2.854,1.924,,0.088,H,A,0.64,-0.85,1.537,,50,HPA,-1.05167,0.168804,0.00237913,0.196825 beta-lactamase_2500_L188D,beta-lactamase_2500_188,TEM-1,beta-lactamase_2500,P62593,0.196836,NO,188,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.166,-3.967,2.801,,,H,A,0.55,-0.3,17.865,17.865,60.14,PHB,-1.47033,0.361275,0.00295687,0.196836 kka2_1:2_D208F,kka2_1:2_208,Kka2,kka2_1:2,P00552,0.196888,NO,208,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.708,-4.32,3.612,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.295029,0.00212588,0.196888 kka2_1:1_L232G,kka2_1:1_232,Kka2,kka2_1:1,P00552,0.196889,NO,232,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.514,-2.969,1.455,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.520039,0.00800103,0.196889 kka2_1:8_V185P,kka2_1:8_185,Kka2,kka2_1:8,P00552,0.196896,NO,185,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.045,-4.002,2.957,,0.058,E,B,1.48,-0.49,1.234,,46.97,HHH,-1.184,0.100394,0.00367031,0.196896 kka2_1:8_V185P,kka2_1:8_185,Kka2,kka2_1:8,P00552,0.196896,NO,185,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.045,-4.002,2.957,,0.058,E,B,1.48,-0.49,1.234,,46.97,HHH,-1.184,0.100394,0.00367031,0.196896 kka2_1:1_G213N,kka2_1:1_213,Kka2,kka2_1:1,P00552,0.196911,NO,213,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.596,-3.476,2.88,,,E,b,0.29,-0.4,,,,HOH,-0.920333,0.520039,0.00187654,0.196911 beta-lactamase_G236W,beta-lactamase_236,TEM-1,beta-lactamase,P62593,0.19697,NO,236,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.784,-5.189,4.405,4.7915,0.241,,b,0.23,-0.59,1.883,,64.69,HOA,-1.36933,0.221079,0.00162372,0.19697 beta-lactamase_625_L223D,beta-lactamase_625_223,TEM-1,beta-lactamase_625,P62593,0.19699,NO,223,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.055,-4.067,3.012,,0.27,,B,0.55,0.09,1.633,,74.48,HHO,-1.35033,0.213352,0.00372793,0.19699 kka2_1:4_F206I,kka2_1:4_206,Kka2,kka2_1:4,P00552,0.19701,NO,206,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.349,-3.398,2.049,,0.006,E,B,0.58,-1.21,1.342,,63.64,OHH,-1.04,0.168804,0.00936868,0.19701 kka2_1:1_Y244E,kka2_1:1_244,Kka2,kka2_1:1,P00552,0.19703,NO,244,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-0.775,-3.693,2.918,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.520039,0.00453187,0.19703 beta-lactamase_2500_S68T,beta-lactamase_2500_68,TEM-1,beta-lactamase_2500,P62593,0.197034,NO,68,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-0.913,-3.02,2.107,,0.064,G,A,0.27,-1.03,2.824,,64.69,HPP,-1.37233,0.361275,0.000800065,0.197034 beta-lactamase_2500_V72Y,beta-lactamase_2500_72,TEM-1,beta-lactamase_2500,P62593,0.197069,NO,72,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.658,-4.055,2.397,,,H,A,0.44,-1.03,2.079,,65.73,BHH,-1.32167,0.361275,0.00501194,0.197069 beta-lactamase_625_M67R,beta-lactamase_625_67,TEM-1,beta-lactamase_625,P62593,0.197072,NO,67,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-2.231,-3.989,1.758,,0.006,G,P,0.55,-0.81,2.653,,65.03,HHP,-1.502,0.213352,0.00409753,0.197072 kka2_1:4_L102Y,kka2_1:4_102,Kka2,kka2_1:4,P00552,0.197103,NO,102,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.804,-3.989,3.185,,,T,A,0.55,-1.17,0.65,,42.42,AHH,-1.398,0.168804,0.00201332,0.197103 kka2_1:1_I2D,kka2_1:1_2,Kka2,kka2_1:1,P00552,0.197122,NO,2,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.787,-3.608,1.821,,,,,,,2.329,,71.59,HHA,-1.92433,0.520039,0.00246644,0.197122 beta-lactamase_2500_T69N,beta-lactamase_2500_69,TEM-1,beta-lactamase_2500,P62593,0.197186,NO,69,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-0.973,-3.537,2.564,,,G,A,0.22,-1.24,2.05,,93.01,PPH,-1.01833,0.361275,0.00127498,0.197186 beta-lactamase_2500_D129A,beta-lactamase_2500_129,TEM-1,beta-lactamase_2500,P62593,0.1972,NO,129,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.816,-3.3,2.484,,,,B,0.75,-0.69,1.29,,34.97,PAP,-0.818,0.361275,0.00109178,0.1972 kka2_1:8_V75P,kka2_1:8_75,Kka2,kka2_1:8,P00552,0.197275,NO,75,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-2.06,-4.189,2.129,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.100394,0.00693733,0.197275 kka2_1:8_V75P,kka2_1:8_75,Kka2,kka2_1:8,P00552,0.197275,NO,75,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-2.06,-4.189,2.129,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.100394,0.00693733,0.197275 beta-lactamase_625_I258H,beta-lactamase_625_258,TEM-1,beta-lactamase_625,P62593,0.197322,NO,258,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.213352,0.007931,0.197322 beta-lactamase_2500_G236E,beta-lactamase_2500_236,TEM-1,beta-lactamase_2500,P62593,0.197338,NO,236,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.784,-3.634,2.85,,0.241,,b,0.29,-0.59,2.14,,64.69,HOO,-1.025,0.361275,0.00162372,0.197338 beta-lactamase_2500_I277G,beta-lactamase_2500_277,TEM-1,beta-lactamase_2500,P62593,0.197381,NO,277,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.361275,0.0169305,0.197381 kka2_1:1_G151W,kka2_1:1_151,Kka2,kka2_1:1,P00552,0.197398,NO,151,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.873,-5.3,4.427,,0.678,T,l,0.29,1.36,0.226,,49.62,HOH,-1.11433,0.520039,0.00339918,0.197398 beta-lactamase_2500_V72D,beta-lactamase_2500_72,TEM-1,beta-lactamase_2500,P62593,0.197447,NO,72,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.658,-3.942,2.284,,,H,A,0.44,-1.03,2.079,,65.73,BHH,-1.32167,0.361275,0.00501194,0.197447 kka2_1:8_G189W,kka2_1:8_189,Kka2,kka2_1:8,P00552,0.197465,NO,189,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.596,-5.126,4.53,,0.034,S,l,0.75,-0.99,,,,BOA,-0.739,0.100394,0.00253688,0.197465 kka2_1:8_G189W,kka2_1:8_189,Kka2,kka2_1:8,P00552,0.197465,NO,189,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.596,-5.126,4.53,,0.034,S,l,0.75,-0.99,,,,BOA,-0.739,0.100394,0.00253688,0.197465 beta-lactamase_156_I244R,beta-lactamase_156_244,TEM-1,beta-lactamase_156,P62593,0.197506,NO,244,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.555,-4.183,2.628,,,E,B,0.48,-0.84,1.325,,77.62,OHH,-1.385,0.111618,0.00605379,0.197506 beta-lactamase_156_V72R,beta-lactamase_156_72,TEM-1,beta-lactamase_156,P62593,0.197524,NO,72,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.658,-4.097,2.439,,,H,A,0.44,-1.03,1.92,,65.73,BHH,-1.32167,0.111618,0.00501194,0.197524 beta-lactamase_A123R,beta-lactamase_123,TEM-1,beta-lactamase,P62593,0.197646,NO,123,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.834,-3.776,2.942,4.70061,0.039,H,A,0.52,-0.72,0.705,,41.26,PHH,-1.47367,0.221079,0.0010157,0.197646 kka2_1:2_D227W,kka2_1:2_227,Kka2,kka2_1:2,P00552,0.197662,NO,227,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.758,-5.454,3.696,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.295029,0.00745029,0.197662 beta-lactamase_39_T178P,beta-lactamase_39_178,TEM-1,beta-lactamase_39,P62593,0.197691,NO,178,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-0.791,-3.655,2.864,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.0495842,0.000684366,0.197691 beta-lactamase_2500_L28D,beta-lactamase_2500_28,TEM-1,beta-lactamase_2500,P62593,0.197735,NO,28,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.579,-3.96,2.381,,0.277,H,A,0.55,-0.16,2.716,,93.01,PHH,-2.11333,0.361275,0.00359321,0.197735 kka2_1:4_G205M,kka2_1:4_205,Kka2,kka2_1:4,P00552,0.197797,NO,205,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.596,-4.958,4.362,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.168804,0.00221855,0.197797 kka2_1:1_H188G,kka2_1:1_188,Kka2,kka2_1:1,P00552,0.197799,NO,188,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-0.913,-3.41,2.497,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.520039,0.00273139,0.197799 beta-lactamase_2500_L219G,beta-lactamase_2500_219,TEM-1,beta-lactamase_2500,P62593,0.197833,NO,219,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.313,-3.865,2.552,,,I,A,0.55,-0.51,35.994,35.994,74.48,HHB,-1.21533,0.361275,0.00664345,0.197833 kka2_1:4_F48Q,kka2_1:4_48,Kka2,kka2_1:4,P00552,0.197917,NO,48,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.453,-4.352,2.899,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.168804,0.00475422,0.197917 beta-lactamase_625_S128R,beta-lactamase_625_128,TEM-1,beta-lactamase_625,P62593,0.198036,NO,128,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-0.84,-3.708,2.868,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.213352,0.00071483,0.198036 beta-lactamase_625_F64H,beta-lactamase_625_64,TEM-1,beta-lactamase_625,P62593,0.198054,NO,64,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-0.841,-4.455,3.614,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.213352,0.000947691,0.198054 beta-lactamase_625_V117D,beta-lactamase_625_117,TEM-1,beta-lactamase_625,P62593,0.198058,NO,117,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.53,-4.116,2.586,,,H,A,0.44,-0.34,1.23,,65.03,PHB,-1.741,0.213352,0.00467906,0.198058 kka2_1:1_V80D,kka2_1:1_80,Kka2,kka2_1:1,P00552,0.198059,NO,80,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.144,-3.971,2.827,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.520039,0.00488211,0.198059 beta-lactamase_39_D177Y,beta-lactamase_39_177,TEM-1,beta-lactamase_39,P62593,0.198086,NO,177,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.967,-4.413,3.446,,0.006,T,L,0.75,-1.02,3.536,,64.69,BAP,-0.873667,0.0495842,0.000864022,0.198086 kka2_1:2_F48C,kka2_1:2_48,Kka2,kka2_1:2,P00552,0.198089,NO,48,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.453,-4.951,3.498,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.295029,0.00475422,0.198089 beta-lactamase_39_S68T,beta-lactamase_39_68,TEM-1,beta-lactamase_39,P62593,0.198096,NO,68,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-0.913,-3.02,2.107,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.0495842,0.000800065,0.198096 beta-lactamase_625_N134K,beta-lactamase_625_134,TEM-1,beta-lactamase_625,P62593,0.198124,NO,134,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-0.879,-2.445,1.566,,0.138,H,A,0.61,-0.6,3.776,,53.15,HPH,-1.02233,0.213352,0.000644786,0.198124 kka2_1:4_I196G,kka2_1:4_196,Kka2,kka2_1:4,P00552,0.198193,NO,196,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-2.115,-3.858,1.743,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.168804,0.0107273,0.198193 beta-lactamase_2500_T107N,beta-lactamase_2500_107,TEM-1,beta-lactamase_2500,P62593,0.198258,NO,107,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.117,-3.473,2.356,,,G,A,0.22,-0.06,2.686,,67.83,HPA,-1.265,0.361275,0.00239347,0.198258 kka2_1:1_A237M,kka2_1:1_237,Kka2,kka2_1:1,P00552,0.198289,NO,237,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.12,-4.281,2.161,,0.068,H,A,0.46,-0.71,2.369,,92.05,HHA,-2.10433,0.520039,0.012257,0.198289 beta-lactamase_625_R59V,beta-lactamase_625_59,TEM-1,beta-lactamase_625,P62593,0.19831,NO,59,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.345,-3.76,2.415,,0.329,S,L,1.2,-0.09,2.995,,73.08,HBO,-2.24267,0.213352,0.00318082,0.19831 kka2_1:4_I228P,kka2_1:4_228,Kka2,kka2_1:4,P00552,0.198314,NO,228,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.142,-4.165,3.023,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.168804,0.00458834,0.198314 kka2_1:4_V97F,kka2_1:4_97,Kka2,kka2_1:4,P00552,0.198329,NO,97,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.453,-3.895,2.442,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.168804,0.00737869,0.198329 kka2_1:1_P109I,kka2_1:1_109,Kka2,kka2_1:1,P00552,0.198335,NO,109,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.412,-3.963,2.551,,0.376,H,A,0.52,-1.25,18.506,18.506,65.53,HOH,-1.84567,0.520039,0.0070929,0.198335 beta-lactamase_2500_N274F,beta-lactamase_2500_274,TEM-1,beta-lactamase_2500,P62593,0.198355,NO,274,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.361275,0.0110418,0.198355 kka2_1:2_F37R,kka2_1:2_37,Kka2,kka2_1:2,P00552,0.1984,NO,37,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.427,-4.151,2.724,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.295029,0.00586193,0.1984 kka2_1:2_I207P,kka2_1:2_207,Kka2,kka2_1:2,P00552,0.198404,NO,207,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.175,-4.149,2.974,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.295029,0.00611824,0.198404 kka2_1:4_V185F,kka2_1:4_185,Kka2,kka2_1:4,P00552,0.198405,NO,185,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.045,-3.962,2.917,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.168804,0.00367031,0.198405 beta-lactamase_2500_A246K,beta-lactamase_2500_246,TEM-1,beta-lactamase_2500,P62593,0.19844,NO,246,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.121,-3.849,1.728,,0.01,E,B,0.46,-1.01,0.753,,73.78,HHH,-1.55633,0.361275,0.00569458,0.19844 kka2_1:1_I196C,kka2_1:1_196,Kka2,kka2_1:1,P00552,0.198488,NO,196,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-2.115,-4.921,2.806,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.520039,0.0107273,0.198488 kka2_1:1_Y218L,kka2_1:1_218,Kka2,kka2_1:1,P00552,0.198488,NO,218,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-1.438,-3.412,1.974,,0.122,H,A,1.25,-0.69,3.059,,56.06,BHP,-1.17533,0.520039,0.0126098,0.198488 kka2_1:4_D183I,kka2_1:4_183,Kka2,kka2_1:4,P00552,0.198492,NO,183,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.204,-3.991,2.787,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.168804,0.00426304,0.198492 kka2_1:8_N195Q,kka2_1:8_195,Kka2,kka2_1:8,P00552,0.198599,NO,195,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-0.836,-3.726,2.89,,0.037,G,A,0.43,-1.36,1.108,,48.11,OPH,-1.26567,0.100394,0.00276134,0.198599 kka2_1:8_N195Q,kka2_1:8_195,Kka2,kka2_1:8,P00552,0.198599,NO,195,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-0.836,-3.726,2.89,,0.037,G,A,0.43,-1.36,1.108,,48.11,OPH,-1.26567,0.100394,0.00276134,0.198599 hsp90_S586A,hsp90_586,hsp90,hsp90,P02829,0.198602,NO,586,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.764,-2.456,0,4.65438,,,B,0.93,0.15,,,,HPH,-3.157,0.368192,0.000222939,0.198602 kka2_1:4_V49S,kka2_1:4_49,Kka2,kka2_1:4,P00552,0.198631,NO,49,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.614,-2.896,1.282,,,E,B,0.44,-0.77,1.233,,64.39,HHB,-1.3,0.168804,0.00615685,0.198631 kka2_1:4_L174D,kka2_1:4_174,Kka2,kka2_1:4,P00552,0.198633,NO,174,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.952,-4.154,3.202,,,H,A,0.55,-0.31,1.339,,51.89,BHB,-2.08533,0.168804,0.00438501,0.198633 beta-lactamase_2500_W288R,beta-lactamase_2500_288,TEM-1,beta-lactamase_2500,P62593,0.198634,NO,288,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,,,,,,,,,,,,,BHO,,0.361275,,0.198634 beta-lactamase_625_S233L,beta-lactamase_625_233,TEM-1,beta-lactamase_625,P62593,0.198709,NO,233,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.886,-3.357,1.471,,0.016,E,B,0.27,-1.01,1.773,,77.62,BPO,-1.17267,0.213352,0.00311415,0.198709 kka2_1:2_I196N,kka2_1:2_196,Kka2,kka2_1:2,P00552,0.198717,NO,196,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-2.115,-4.284,2.169,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.295029,0.0107273,0.198717 kka2_1:1_V113K,kka2_1:1_113,Kka2,kka2_1:1,P00552,0.198723,NO,113,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.233,-3.874,2.641,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.520039,0.00650191,0.198723 beta-lactamase_625_I125E,beta-lactamase_625_125,TEM-1,beta-lactamase_625,P62593,0.198736,NO,125,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.441,-3.878,2.437,,,H,A,0.48,-0.7,2.034,,63.29,HHP,-1.248,0.213352,0.00383964,0.198736 kka2_1:2_C192A,kka2_1:2_192,Kka2,kka2_1:2,P00552,0.198763,NO,192,C,A,CA,Special,Hydrophobic,5.07,6,0.93,195,121,89,-32,108.5,88.6,-19.9,-1.067,-2.954,1.887,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.295029,0.00485428,0.198763 kka2_1:2_I246P,kka2_1:2_246,Kka2,kka2_1:2,P00552,0.198763,NO,246,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-2.008,-3.255,1.247,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.295029,0.0139479,0.198763 kka2_1:8_G245W,kka2_1:8_245,Kka2,kka2_1:8,P00552,0.198787,NO,245,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.812,-5.257,4.445,,0.655,T,g,0.75,0.03,1.148,,65.53,HOH,-1.19833,0.100394,0.00683899,0.198787 kka2_1:8_G245W,kka2_1:8_245,Kka2,kka2_1:8,P00552,0.198787,NO,245,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.812,-5.257,4.445,,0.655,T,g,0.75,0.03,1.148,,65.53,HOH,-1.19833,0.100394,0.00683899,0.198787 kka2_1:1_R44I,kka2_1:1_44,Kka2,kka2_1:1,P00552,0.198823,NO,44,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.062,-4.031,1.969,,0.487,S,B,1.2,-0.35,2.717,,71.59,OBO,-1.80767,0.520039,0.00745043,0.198823 beta-lactamase_625_F70P,beta-lactamase_625_70,TEM-1,beta-lactamase_625,P62593,0.198829,NO,70,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.169,-4.211,3.042,,,H,A,0.58,-1.34,1.14,,63.99,PHB,-0.980667,0.213352,0.00193499,0.198829 beta-lactamase_2500_L191D,beta-lactamase_2500_191,TEM-1,beta-lactamase_2500,P62593,0.19887,NO,191,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.087,-4.092,3.005,,,H,A,0.55,0.09,1.703,,63.29,BHH,-1.445,0.361275,0.00263549,0.19887 beta-lactamase_625_A124R,beta-lactamase_625_124,TEM-1,beta-lactamase_625,P62593,0.198915,NO,124,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.181,-3.827,2.646,,,H,A,0.46,-0.9,2.027,,64.34,HHH,-1.152,0.213352,0.00481399,0.198915 kka2_1:1_V242I,kka2_1:1_242,Kka2,kka2_1:1,P00552,0.198926,NO,242,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-2.687,-3.231,0.544,,0.75,H,A,0.44,-0.37,4.987,,71.59,HHH,-2.16533,0.520039,0.0102575,0.198926 beta-lactamase_156_Y44N,beta-lactamase_156_44,TEM-1,beta-lactamase_156,P62593,0.19893,NO,44,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-2.547,-4.162,1.615,,,E,B,0.21,-0.45,2.184,,73.78,OHH,-1.86267,0.111618,0.00426364,0.19893 beta-lactamase_39_A133L,beta-lactamase_39_133,TEM-1,beta-lactamase_39,P62593,0.198943,NO,133,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.186,-3.396,2.21,,,H,A,0.46,-0.86,0.373,,67.83,HHP,-0.988333,0.0495842,0.00468022,0.198943 kka2_1:4_F264I,kka2_1:4_264,Kka2,kka2_1:4,P00552,0.198954,NO,264,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.02,-3.433,2.413,,0.296,,?,1.62,0.02,1.93,,71.59,HHO,-0.9655,0.168804,,0.198954 kka2_1:8_L223G,kka2_1:8_223,Kka2,kka2_1:8,P00552,0.198976,NO,223,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.861,-3.881,3.02,,,H,A,1.59,-1.24,1.017,,50,HHH,-0.854333,0.100394,0.00253574,0.198976 kka2_1:8_L223G,kka2_1:8_223,Kka2,kka2_1:8,P00552,0.198976,NO,223,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.861,-3.881,3.02,,,H,A,1.59,-1.24,1.017,,50,HHH,-0.854333,0.100394,0.00253574,0.198976 kka2_1:8_V113Q,kka2_1:8_113,Kka2,kka2_1:8,P00552,0.198976,NO,113,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.233,-4.296,3.063,,0.008,H,A,1.48,-1.17,1.254,,52.27,BHP,-2.08367,0.100394,0.00650191,0.198976 kka2_1:8_V113Q,kka2_1:8_113,Kka2,kka2_1:8,P00552,0.198976,NO,113,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.233,-4.296,3.063,,0.008,H,A,1.48,-1.17,1.254,,52.27,BHP,-2.08367,0.100394,0.00650191,0.198976 beta-lactamase_625_S241I,beta-lactamase_625_241,TEM-1,beta-lactamase_625,P62593,0.198981,NO,241,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.213352,0.00452736,0.198981 kka2_1:1_A176V,kka2_1:1_176,Kka2,kka2_1:1,P00552,0.199013,NO,176,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.621,-3.617,1.996,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.520039,0.0083587,0.199013 kka2_1:1_F264I,kka2_1:1_264,Kka2,kka2_1:1,P00552,0.199044,NO,264,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.02,-3.433,2.413,,0.296,.,?,0.58,0.02,2.303,,71.59,HHNA,-0.9655,0.520039,,0.199044 beta-lactamase_625_S68A,beta-lactamase_625_68,TEM-1,beta-lactamase_625,P62593,0.199071,NO,68,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-0.913,-2.711,1.798,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.213352,0.000800065,0.199071 beta-lactamase_156_I280G,beta-lactamase_156_280,TEM-1,beta-lactamase_156,P62593,0.199112,NO,280,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.111618,0.0530888,0.199112 kka2_1:8_Y244E,kka2_1:8_244,Kka2,kka2_1:8,P00552,0.199164,NO,244,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-0.775,-3.693,2.918,,0.066,H,A,1.25,-0.64,,,,HHO,-1.41267,0.100394,0.00453187,0.199164 kka2_1:8_Y244E,kka2_1:8_244,Kka2,kka2_1:8,P00552,0.199164,NO,244,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-0.775,-3.693,2.918,,0.066,H,A,1.25,-0.64,,,,HHO,-1.41267,0.100394,0.00453187,0.199164 kka2_1:4_F206Q,kka2_1:4_206,Kka2,kka2_1:4,P00552,0.199182,NO,206,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.349,-4.252,2.903,,0.006,E,B,0.58,-1.21,1.342,,63.64,OHH,-1.04,0.168804,0.00936868,0.199182 beta-lactamase_625_V72D,beta-lactamase_625_72,TEM-1,beta-lactamase_625,P62593,0.199207,NO,72,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.658,-3.942,2.284,,,H,A,0.44,-1.03,0.981,,65.73,BHH,-1.32167,0.213352,0.00501194,0.199207 beta-lactamase_156_Y262E,beta-lactamase_156_262,TEM-1,beta-lactamase_156,P62593,0.199308,NO,262,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.111618,0.00853516,0.199308 beta-lactamase_39_G234I,beta-lactamase_39_234,TEM-1,beta-lactamase_39,P62593,0.199329,NO,234,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.62,-4.235,3.615,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.0495842,0.000889577,0.199329 kka2_1:8_F203Y,kka2_1:8_203,Kka2,kka2_1:8,P00552,0.199353,NO,203,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-0.911,-3.189,2.278,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.100394,0.00318738,0.199353 kka2_1:8_F203Y,kka2_1:8_203,Kka2,kka2_1:8,P00552,0.199353,NO,203,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-0.911,-3.189,2.278,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.100394,0.00318738,0.199353 kka2_1:8_L47E,kka2_1:8_47,Kka2,kka2_1:8,P00552,0.199353,NO,47,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.265,-3.747,2.482,,0.139,E,B,1.59,-0.86,5.086,,63.26,HHH,-1.77933,0.100394,0.00509386,0.199353 kka2_1:8_L47E,kka2_1:8_47,Kka2,kka2_1:8,P00552,0.199353,NO,47,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.265,-3.747,2.482,,0.139,E,B,1.59,-0.86,5.086,,63.26,HHH,-1.77933,0.100394,0.00509386,0.199353 beta-lactamase_39_S128V,beta-lactamase_39_128,TEM-1,beta-lactamase_39,P62593,0.199362,NO,128,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-0.84,-3.529,2.689,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.0495842,0.00071483,0.199362 beta-lactamase_156_E35P,beta-lactamase_156_35,TEM-1,beta-lactamase_156,P62593,0.199417,NO,35,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-0.869,-3.68,2.811,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.111618,0.00174441,0.199417 beta-lactamase_39_A124H,beta-lactamase_39_124,TEM-1,beta-lactamase_39,P62593,0.199437,NO,124,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.181,-4.785,3.604,,,H,A,0.46,-0.9,1.367,,64.34,HHH,-1.152,0.0495842,0.00481399,0.199437 beta-lactamase_156_S68D,beta-lactamase_156_68,TEM-1,beta-lactamase_156,P62593,0.199441,NO,68,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-0.913,-3.241,2.328,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.111618,0.000800065,0.199441 beta-lactamase_2500_I244K,beta-lactamase_2500_244,TEM-1,beta-lactamase_2500,P62593,0.199503,NO,244,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.555,-3.812,2.257,,,E,B,0.48,-0.84,1.683,,77.62,OHH,-1.385,0.361275,0.00605379,0.199503 kka2_1:8_V113G,kka2_1:8_113,Kka2,kka2_1:8,P00552,0.199541,NO,113,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.233,-3.759,2.526,,0.008,H,A,1.48,-1.17,1.254,,52.27,BHP,-2.08367,0.100394,0.00650191,0.199541 kka2_1:8_V113G,kka2_1:8_113,Kka2,kka2_1:8,P00552,0.199541,NO,113,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.233,-3.759,2.526,,0.008,H,A,1.48,-1.17,1.254,,52.27,BHP,-2.08367,0.100394,0.00650191,0.199541 kka2_1:1_D159I,kka2_1:1_159,Kka2,kka2_1:1,P00552,0.199588,NO,159,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.82,-4.102,3.282,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.520039,0.0030485,0.199588 beta-lactamase_2500_T179D,beta-lactamase_2500_179,TEM-1,beta-lactamase_2500,P62593,0.199601,NO,179,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.085,-3.517,2.432,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.361275,0.00226045,0.199601 kka2_1:2_H135E,kka2_1:2_135,Kka2,kka2_1:2,P00552,0.199631,NO,135,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-1.331,-3.297,1.966,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.295029,0.00532566,0.199631 beta-lactamase_2500_A123M,beta-lactamase_2500_123,TEM-1,beta-lactamase_2500,P62593,0.199645,NO,123,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.834,-4.443,3.609,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.361275,0.0010157,0.199645 beta-lactamase_L192K,beta-lactamase_192,TEM-1,beta-lactamase,P62593,0.199651,NO,192,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.254,-3.803,2.549,5.68899,0.095,H,A,1.3,0.35,1.756,,60.14,HHP,-1.41833,0.221079,0.00558728,0.199651 beta-lactamase_2500_D83F,beta-lactamase_2500_83,TEM-1,beta-lactamase_2500,P62593,0.199671,NO,83,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.066,-4.344,3.278,,0.354,H,A,0.75,0.22,0.239,,48.95,HAH,-1.34733,0.361275,0.00205968,0.199671 beta-lactamase_2500_V260Q,beta-lactamase_2500_260,TEM-1,beta-lactamase_2500,P62593,0.199693,NO,260,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.361275,0.00471757,0.199693 kka2_1:4_H188V,kka2_1:4_188,Kka2,kka2_1:4,P00552,0.199722,NO,188,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-0.913,-3.78,2.867,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.168804,0.00273139,0.199722 kka2_1:8_D208Q,kka2_1:8_208,Kka2,kka2_1:8,P00552,0.199729,NO,208,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.708,-3.703,2.995,,0.36,,l,0.29,-1.01,,,,HAO,-0.929667,0.100394,0.00212588,0.199729 kka2_1:8_D208Q,kka2_1:8_208,Kka2,kka2_1:8,P00552,0.199729,NO,208,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.708,-3.703,2.995,,0.36,,l,0.29,-1.01,,,,HAO,-0.929667,0.100394,0.00212588,0.199729 beta-lactamase_156_I258K,beta-lactamase_156_258,TEM-1,beta-lactamase_156,P62593,0.199752,NO,258,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.111618,0.007931,0.199752 kka2_1:4_V214S,kka2_1:4_214,Kka2,kka2_1:4,P00552,0.199781,NO,214,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.261,-3.744,2.483,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.168804,0.00692782,0.199781 beta-lactamase_156_S128N,beta-lactamase_156_128,TEM-1,beta-lactamase_156,P62593,0.199782,NO,128,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-0.84,-3.223,2.383,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.111618,0.00071483,0.199782 kka2_1:4_L107N,kka2_1:4_107,Kka2,kka2_1:4,P00552,0.199819,NO,107,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.238,-4.107,2.869,,0.197,.,B,0.55,-1.1,0.398,,71.59,BHH,-2.143,0.168804,0.00561937,0.199819 beta-lactamase_156_G234R,beta-lactamase_156_234,TEM-1,beta-lactamase_156,P62593,0.199824,NO,234,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.62,-3.933,3.313,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.111618,0.000889577,0.199824 beta-lactamase_2500_L284R,beta-lactamase_2500_284,TEM-1,beta-lactamase_2500,P62593,0.19986,NO,284,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.361275,0.0686156,0.19986 beta-lactamase_625_F64G,beta-lactamase_625_64,TEM-1,beta-lactamase_625,P62593,0.199877,NO,64,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-0.841,-3.583,2.742,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.213352,0.000947691,0.199877 hsp90_S586C,hsp90_586,hsp90,hsp90,P02829,0.199889,NO,586,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.764,-4.015,0,4.65438,,,B,0.93,0.15,,,,HPH,-3.157,0.368192,0.000222939,0.199889 Pab1_I128G,Pab1_128,Pab1,Pab1,P04147,0.199908,NO,128,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.345,-3.622,2.277,,0.008,E,B,1.68,-0.6,1.706,,78.68,PHH,-1.231,0.175299,0.00104192,0.199908 kka2_1:8_I207K,kka2_1:8_207,Kka2,kka2_1:8,P00552,0.199917,NO,207,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.175,-3.925,2.75,,0.293,,B,1.52,-1.12,1.306,,56.06,HHA,-1.07733,0.100394,0.00611824,0.199917 kka2_1:8_I207K,kka2_1:8_207,Kka2,kka2_1:8,P00552,0.199917,NO,207,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.175,-3.925,2.75,,0.293,,B,1.52,-1.12,1.306,,56.06,HHA,-1.07733,0.100394,0.00611824,0.199917 kka2_1:2_H188E,kka2_1:2_188,Kka2,kka2_1:2,P00552,0.199944,NO,188,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-0.913,-3.211,2.298,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.295029,0.00273139,0.199944 beta-lactamase_156_F149P,beta-lactamase_156_149,TEM-1,beta-lactamase_156,P62593,0.199976,NO,149,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.299,-4.282,2.983,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.111618,0.00418462,0.199976 kka2_1:1_R38W,kka2_1:1_38,Kka2,kka2_1:1,P00552,0.199988,NO,38,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.207,-5.334,4.127,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.520039,0.00372499,0.199988 beta-lactamase_625_S68R,beta-lactamase_625_68,TEM-1,beta-lactamase_625,P62593,0.200115,NO,68,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-0.913,-3.705,2.792,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.213352,0.000800065,0.200115 kka2_1:1_L19C,kka2_1:1_19,Kka2,kka2_1:1,P00552,0.200221,NO,19,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.254,-4.888,3.634,,0.08,T,A,0.55,-0.26,17.165,17.165,65.53,BHH,-2.221,0.520039,0.00620703,0.200221 beta-lactamase_2500_R242W,beta-lactamase_2500_242,TEM-1,beta-lactamase_2500,P62593,0.200228,NO,242,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.361275,0.00452879,0.200228 beta-lactamase_156_A132P,beta-lactamase_156_132,TEM-1,beta-lactamase_156,P62593,0.200229,NO,132,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.9,-3.725,2.825,,,H,A,0.46,-0.93,10.621,,64.69,PHH,-1.138,0.111618,0.000962524,0.200229 kka2_1:4_R66W,kka2_1:4_66,Kka2,kka2_1:4,P00552,0.200262,NO,66,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-0.922,-5.385,4.463,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.168804,0.00161025,0.200262 beta-lactamase_39_A132E,beta-lactamase_39_132,TEM-1,beta-lactamase_39,P62593,0.200328,NO,132,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.9,-3.484,2.584,,,H,A,0.46,-0.93,8.408,,64.69,PHH,-1.138,0.0495842,0.000962524,0.200328 kka2_1:1_L193Y,kka2_1:1_193,Kka2,kka2_1:1,P00552,0.200399,NO,193,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.983,-4.078,3.095,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.520039,0.00480179,0.200399 beta-lactamase_156_M209Y,beta-lactamase_156_209,TEM-1,beta-lactamase_156,P62593,0.20044,NO,209,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.442,-3.865,2.423,,,H,A,0.55,-0.97,1.066,,64.69,HHA,-1.52633,0.111618,0.00625021,0.20044 kka2_1:2_H188V,kka2_1:2_188,Kka2,kka2_1:2,P00552,0.200476,NO,188,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-0.913,-3.78,2.867,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.295029,0.00273139,0.200476 kka2_1:8_Q219D,kka2_1:8_219,Kka2,kka2_1:8,P00552,0.20048,NO,219,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-0.93,-3.333,2.403,,0.088,H,A,0.4,-0.85,0.897,,50,HPA,-1.05167,0.100394,0.00237913,0.20048 kka2_1:8_Q219D,kka2_1:8_219,Kka2,kka2_1:8,P00552,0.20048,NO,219,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-0.93,-3.333,2.403,,0.088,H,A,0.4,-0.85,0.897,,50,HPA,-1.05167,0.100394,0.00237913,0.20048 beta-lactamase_2500_A123N,beta-lactamase_2500_123,TEM-1,beta-lactamase_2500,P62593,0.200508,NO,123,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.834,-3.947,3.113,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.361275,0.0010157,0.200508 beta-lactamase_156_I280S,beta-lactamase_156_280,TEM-1,beta-lactamase_156,P62593,0.200521,NO,280,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.111618,0.0530888,0.200521 beta-lactamase_2500_T69V,beta-lactamase_2500_69,TEM-1,beta-lactamase_2500,P62593,0.200522,NO,69,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-0.973,-3.175,2.202,,,G,A,0.22,-1.24,2.05,,93.01,PPH,-1.01833,0.361275,0.00127498,0.200522 beta-lactamase_2500_T126Y,beta-lactamase_2500_126,TEM-1,beta-lactamase_2500,P62593,0.200536,NO,126,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.122,-4.294,3.172,,0.05,H,A,0.22,-0.05,0.817,,44.41,HPH,-1.60467,0.361275,0.00244552,0.200536 beta-lactamase_625_A185Y,beta-lactamase_625_185,TEM-1,beta-lactamase_625,P62593,0.200559,NO,185,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.406,-4.227,2.821,,,H,A,0.46,-1.02,0.365,,65.03,HHP,-1.84033,0.213352,0.00467449,0.200559 beta-lactamase_625_L167K,beta-lactamase_625_167,TEM-1,beta-lactamase_625,P62593,0.200563,NO,167,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.138,-3.594,2.456,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.213352,0.00303566,0.200563 kka2_1:1_A137W,kka2_1:1_137,Kka2,kka2_1:1,P00552,0.200615,NO,137,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.156,-2.974,0.818,,0.029,H,A,0.46,0.34,1.323,,63.26,PHB,-2.559,0.520039,0.00515054,0.200615 kka2_1:2_Q136W,kka2_1:2_136,Kka2,kka2_1:2,P00552,0.200631,NO,136,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-3.021,-5.446,2.425,,0.331,,b,0.4,0.96,2.726,,92.05,BPH,-2.16933,0.295029,0.00624149,0.200631 kka2_1:1_V186W,kka2_1:1_186,Kka2,kka2_1:1,P00552,0.200687,NO,186,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.011,-5.309,4.298,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.520039,0.00409703,0.200687 beta-lactamase_156_G234E,beta-lactamase_156_234,TEM-1,beta-lactamase_156,P62593,0.200688,NO,234,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.62,-3.665,3.045,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.111618,0.000889577,0.200688 kka2_1:4_Y244G,kka2_1:4_244,Kka2,kka2_1:4,P00552,0.200689,NO,244,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-0.775,-3.611,2.836,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.168804,0.00453187,0.200689 kka2_1:1_E96N,kka2_1:1_96,Kka2,kka2_1:1,P00552,0.200692,NO,96,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.573,-3.878,1.305,,0.476,,B,1.52,-0.65,1.254,,71.59,OAH,-2.143,0.520039,0.00369441,0.200692 kka2_1:1_E262Y,kka2_1:1_262,Kka2,kka2_1:1,P00552,0.200711,NO,262,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-0.829,-4.189,3.36,,0.059,G,A,1.04,-0.18,0.837,,42.42,AAH,-0.816,0.520039,0.0191586,0.200711 kka2_1:1_V214R,kka2_1:1_214,Kka2,kka2_1:1,P00552,0.200764,NO,214,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.261,-3.109,1.848,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.520039,0.00692782,0.200764 beta-lactamase_625_G249L,beta-lactamase_625_249,TEM-1,beta-lactamase_625,P62593,0.200848,NO,249,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.213352,0.00220169,0.200848 beta-lactamase_156_D129H,beta-lactamase_156_129,TEM-1,beta-lactamase_156,P62593,0.200868,NO,129,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.816,-4.453,3.637,,,,B,0.75,-0.69,1.924,,34.97,PAP,-0.818,0.111618,0.00109178,0.200868 PSD95pdz3_G329C,PSD95pdz3_329,PSD95pdz3,PSD95pdz3,P31016,0.200909,NO,329,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.008,-4.769,3.761,4.7671,,,,,19.7075,,,,HOO,-1.16033,0.0758425,0.000974577,0.200909 beta-lactamase_0_V72E,beta-lactamase_0_72,TEM-1,beta-lactamase_0,P62593,0.201001,NO,72,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.658,-3.755,2.097,,,H,A,0.44,-1.03,2.964,,65.73,BHH,-1.32167,0.0500837,0.00501194,0.201001 beta-lactamase_M1W,beta-lactamase_1,TEM-1,beta-lactamase,P62593,0.201009,NO,1,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.998,-4.554,2.556,,,,,,,,,,OHP,-1.97,0.221079,0.00162771,0.201009 beta-lactamase_S68C,beta-lactamase_68,TEM-1,beta-lactamase,P62593,0.201063,NO,68,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-0.913,-4.705,3.792,4.94745,0.064,G,A,0.77,-1.03,3.202,,64.69,HPP,-1.37233,0.221079,0.000800065,0.201063 kka2_1:2_E96W,kka2_1:2_96,Kka2,kka2_1:2,P00552,0.201075,NO,96,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.573,-5.436,2.863,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.295029,0.00369441,0.201075 beta-lactamase_2500_G234L,beta-lactamase_2500_234,TEM-1,beta-lactamase_2500,P62593,0.201089,NO,234,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.62,-3.808,3.188,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.361275,0.000889577,0.201089 beta-lactamase_2500_W288Q,beta-lactamase_2500_288,TEM-1,beta-lactamase_2500,P62593,0.201102,NO,288,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,,,,,,,,,,,,,BHO,,0.361275,,0.201102 beta-lactamase_2500_Y95K,beta-lactamase_2500_95,TEM-1,beta-lactamase_2500,P62593,0.201144,NO,95,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-1.715,-3.936,2.221,,0.122,,b,0.21,-0.37,2.914,,77.62,BHP,-2.16167,0.361275,0.00479449,0.201144 kka2_1:2_V185Q,kka2_1:2_185,Kka2,kka2_1:2,P00552,0.201153,NO,185,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.045,-4.205,3.16,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.295029,0.00367031,0.201153 beta-lactamase_156_L146P,beta-lactamase_156_146,TEM-1,beta-lactamase_156,P62593,0.201164,NO,146,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.462,-4.216,2.754,,0.007,H,A,0.55,-0.56,1.578,,64.69,AHP,-1.656,0.111618,0.00474542,0.201164 beta-lactamase_625_I261G,beta-lactamase_625_261,TEM-1,beta-lactamase_625,P62593,0.201165,NO,261,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.213352,0.0123091,0.201165 kka2_1:2_V75K,kka2_1:2_75,Kka2,kka2_1:2,P00552,0.201174,NO,75,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-2.06,-3.819,1.759,,0.042,.,B,0.44,-0.2,2.815,,71.59,OHO,-1.563,0.295029,0.00693733,0.201174 kka2_1:2_D220E,kka2_1:2_220,Kka2,kka2_1:2,P00552,0.201191,NO,220,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.787,-2.878,2.091,,,H,A,0.75,-1.14,0.745,,46.59,PAH,-1.152,0.295029,0.00158066,0.201191 kka2_1:2_D52F,kka2_1:2_52,Kka2,kka2_1:2,P00552,0.201199,NO,52,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.271,-4.344,2.073,,0.22,E,B,0.75,0.8,1.123,,71.59,PAH,-2.38367,0.295029,0.00175694,0.201199 kka2_1:8_L123W,kka2_1:8_123,Kka2,kka2_1:8,P00552,0.20123,NO,123,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.888,-5.165,4.277,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.100394,0.00325188,0.20123 kka2_1:8_L123W,kka2_1:8_123,Kka2,kka2_1:8,P00552,0.20123,NO,123,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.888,-5.165,4.277,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.100394,0.00325188,0.20123 beta-lactamase_625_R162I,beta-lactamase_625_162,TEM-1,beta-lactamase_625,P62593,0.201259,NO,162,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.016,-3.867,2.851,,0.124,S,B,1.2,-0.37,1.445,,64.69,ABH,-1.25,0.213352,0.000561334,0.201259 beta-lactamase_625_V42R,beta-lactamase_625_42,TEM-1,beta-lactamase_625,P62593,0.201276,NO,42,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.564,-4.138,2.574,,0.017,E,B,0.44,-0.51,2.576,,63.99,BHO,-1.042,0.213352,0.00404515,0.201276 kka2_1:1_P45I,kka2_1:1_45,Kka2,kka2_1:1,P00552,0.201303,NO,45,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.774,-4.097,2.323,,0.669,.,B,0.52,-0.76,4.882,,71.59,BOH,-2.152,0.520039,0.00590481,0.201303 kka2_1:1_V80M,kka2_1:1_80,Kka2,kka2_1:1,P00552,0.201339,NO,80,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.144,-4.231,3.087,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.520039,0.00488211,0.201339 beta-lactamase_2500_G243R,beta-lactamase_2500_243,TEM-1,beta-lactamase_2500,P62593,0.201355,NO,243,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.361275,0.00464034,0.201355 kka2_1:2_D261A,kka2_1:2_261,Kka2,kka2_1:2,P00552,0.201364,NO,261,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.708,-3.331,2.623,,0.146,G,A,0.75,-0.33,,,,HAA,-0.759333,0.295029,0.0224846,0.201364 kka2_1:1_H162E,kka2_1:1_162,Kka2,kka2_1:1,P00552,0.201399,NO,162,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-2.319,-3.397,1.078,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.520039,0.00616145,0.201399 beta-lactamase_2500_V78E,beta-lactamase_2500_78,TEM-1,beta-lactamase_2500,P62593,0.201414,NO,78,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.459,-3.911,2.452,,,H,A,0.44,-0.47,31.376,31.376,63.64,HHH,-1.17833,0.361275,0.00492501,0.201414 kka2_1:4_A144D,kka2_1:4_144,Kka2,kka2_1:4,P00552,0.201416,NO,144,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.859,-3.804,2.945,,,H,A,0.46,0.21,6.844,,52.65,BHB,-1.72933,0.168804,0.00231095,0.201416 kka2_1:2_D52K,kka2_1:2_52,Kka2,kka2_1:2,P00552,0.201462,NO,52,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.271,-3.096,0.825,,0.22,E,B,0.75,0.8,1.123,,71.59,PAH,-2.38367,0.295029,0.00175694,0.201462 beta-lactamase_2500_A246Y,beta-lactamase_2500_246,TEM-1,beta-lactamase_2500,P62593,0.201474,NO,246,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.121,-4.018,1.897,,0.01,E,B,0.46,-1.01,0.753,,73.78,HHH,-1.55633,0.361275,0.00569458,0.201474 kka2_1:4_I228A,kka2_1:4_228,Kka2,kka2_1:4,P00552,0.201492,NO,228,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.142,-3.138,1.996,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.168804,0.00458834,0.201492 kka2_1:4_R258Y,kka2_1:4_258,Kka2,kka2_1:4,P00552,0.201524,NO,258,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.626,-4.283,2.657,,0.316,H,A,1.2,-0.85,2.655,,53.03,HBH,-1.25933,0.168804,0.00983174,0.201524 gb1_A249Y,gb1_249,gb1,gb1,P06654,0.201584,NO,249,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.739,-4.04,2.301,,,,,,,0.252,,44.87,AHH,-1.67367,0.177985,0.00333585,0.201584 gb1_A252E,gb1_252,gb1,gb1,P06654,0.201584,NO,252,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.175,-3.175,2,,,,,,,,,,PHA,-1.55967,0.177985,0.00125598,0.201584 gb1_A252F,gb1_252,gb1,gb1,P06654,0.201584,NO,252,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.175,-3.803,2.628,,,,,,,,,,PHA,-1.55967,0.177985,0.00125598,0.201584 gb1_A252H,gb1_252,gb1,gb1,P06654,0.201584,NO,252,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.175,-4.416,3.241,,,,,,,,,,PHA,-1.55967,0.177985,0.00125598,0.201584 gb1_F278T,gb1_278,gb1,gb1,P06654,0.201584,NO,278,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.418,-3.417,1.999,,,,,,,3.233,,35.71,PHP,-1.503,0.177985,0.00295699,0.201584 gb1_F278W,gb1_278,gb1,gb1,P06654,0.201584,NO,278,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.418,-4.448,3.03,,,,,,,3.233,,35.71,PHP,-1.503,0.177985,0.00295699,0.201584 gb1_G264P,gb1_264,gb1,gb1,P06654,0.201584,NO,264,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.833,-3.851,2.018,,,,,,,0.864,,44.87,POH,-1.61267,0.177985,0.0049716,0.201584 gb1_K257C,gb1_257,gb1,gb1,P06654,0.201584,NO,257,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.775,-4.976,3.201,,,,,,,0.896,,37.28,HBP,-1.70367,0.177985,0.00640304,0.201584 gb1_L231E,gb1_231,gb1,gb1,P06654,0.201584,NO,231,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.603,-3.582,1.979,,,,,,,0.219,,11.83,BHH,-1.82633,0.177985,0.00322797,0.201584 gb1_L231P,gb1_231,gb1,gb1,P06654,0.201584,NO,231,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.603,-3.916,2.313,,,,,,,0.219,,11.83,BHH,-1.82633,0.177985,0.00322797,0.201584 gb1_N261D,gb1_261,gb1,gb1,P06654,0.201584,NO,261,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-1.863,-3.115,1.252,,,,,,,1.191,,44.87,HPA,-2.16033,0.177985,0.0061875,0.201584 gb1_N261E,gb1_261,gb1,gb1,P06654,0.201584,NO,261,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-1.863,-3.173,1.31,,,,,,,1.191,,44.87,HPA,-2.16033,0.177985,0.0061875,0.201584 gb1_N261K,gb1_261,gb1,gb1,P06654,0.201584,NO,261,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-1.863,-3.19,1.327,,,,,,,1.191,,44.87,HPA,-2.16033,0.177985,0.0061875,0.201584 gb1_V265G,gb1_265,gb1,gb1,P06654,0.201584,NO,265,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.843,-1.588,-0.255,,,,,,,0.402,,11.83,OHA,-1.64567,0.177985,0.00360613,0.201584 gb1_V280K,gb1_280,gb1,gb1,P06654,0.201584,NO,280,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.764,-3.457,1.693,,,,,,,0.874,,35.71,PHP,-1.63733,0.177985,0.00321577,0.201584 gb1_V280P,gb1_280,gb1,gb1,P06654,0.201584,NO,280,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.764,-3.702,1.938,,,,,,,0.874,,35.71,PHP,-1.63733,0.177985,0.00321577,0.201584 gb1_Y271P,gb1_271,gb1,gb1,P06654,0.201584,NO,271,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-1.181,-3.882,2.701,,,,,,,,,,PHA,-1.92933,0.177985,0.00236544,0.201584 kka2_1:4_L259K,kka2_1:4_259,Kka2,kka2_1:4,P00552,0.20159,NO,259,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.088,-3.716,2.628,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.168804,0.0206964,0.20159 Ubiquitin_G75I,Ubiquitin_75,Uba1,Ubiquitin,P0CG48,0.201613,NO,75,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.613,-4.009,2.396,5.44099,0.552,T,A,0.73,0.9,4.017,,34.31,BOO,-1.66767,0.205827,0.000712673,0.201613 Ubiquitin_G76R,Ubiquitin_76,Uba1,Ubiquitin,P0CG48,0.201613,NO,76,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.651,-3.905,2.254,5.7647,0.23,,B,0.12,0.08,9.665,9.665,34.31,OOO,-1.632,0.205827,0.000653872,0.201613 Ubiquitin_R72I,Ubiquitin_72,Uba1,Ubiquitin,P0CG48,0.201613,NO,72,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.034,-3.055,1.021,5.19484,0.077,,B,1.41,-0.1,9.638,9.638,42.77,HBH,-1.82733,0.205827,0.000768249,0.201613 kka2_1:2_L126A,kka2_1:2_126,Kka2,kka2_1:2,P00552,0.201691,NO,126,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.246,-3.18,1.934,,0.285,S,B,0.55,0.12,1.392,,51.89,PHA,-1.744,0.295029,0.0066485,0.201691 kka2_1:1_V214F,kka2_1:1_214,Kka2,kka2_1:1,P00552,0.201692,NO,214,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.261,-3.945,2.684,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.520039,0.00692782,0.201692 beta-lactamase_625_G234W,beta-lactamase_625_234,TEM-1,beta-lactamase_625,P62593,0.20172,NO,234,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.62,-5.097,4.477,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.213352,0.000889577,0.20172 beta-lactamase_S233N,beta-lactamase_233,TEM-1,beta-lactamase,P62593,0.201737,NO,233,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.886,-2.73,0.844,4.98121,0.016,E,B,0.48,-1.01,5.361,,77.62,BPO,-1.17267,0.221079,0.00311415,0.201737 kka2_1:1_Y218K,kka2_1:1_218,Kka2,kka2_1:1,P00552,0.20178,NO,218,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-1.438,-3.819,2.381,,0.122,H,A,1.25,-0.69,3.059,,56.06,BHP,-1.17533,0.520039,0.0126098,0.20178 kka2_1:2_R38W,kka2_1:2_38,Kka2,kka2_1:2,P00552,0.201807,NO,38,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.207,-5.334,4.127,,0.355,E,B,1.2,-1.13,6.872,6.872,52.27,HBH,-1.28567,0.295029,0.00372499,0.201807 kka2_1:4_I141K,kka2_1:4_141,Kka2,kka2_1:4,P00552,0.201813,NO,141,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.495,-3.912,2.417,,0.068,H,A,0.48,-0.01,2.144,,92.05,BHA,-1.689,0.168804,0.00744745,0.201813 kka2_1:1_G164T,kka2_1:1_164,Kka2,kka2_1:1,P00552,0.201838,NO,164,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.869,-3.578,2.709,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.520039,0.00442091,0.201838 kka2_1:2_R253T,kka2_1:2_253,Kka2,kka2_1:2,P00552,0.201846,NO,253,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.356,-3.535,2.179,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.295029,0.0144195,0.201846 kka2_1:4_A224F,kka2_1:4_224,Kka2,kka2_1:4,P00552,0.201887,NO,224,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.977,-4.161,3.184,,,H,A,0.46,-1.26,0.93,,63.64,HHP,-1.41033,0.168804,0.00352047,0.201887 beta-lactamase_2500_N168H,beta-lactamase_2500_168,TEM-1,beta-lactamase_2500,P62593,0.201895,NO,168,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-1.029,-4.17,3.141,,0.113,G,A,0.61,-0.4,2.9,,44.41,HPA,-1.13233,0.361275,0.00288667,0.201895 PSD95pdz3_G324W,PSD95pdz3_324,PSD95pdz3,PSD95pdz3,P31016,0.201906,NO,324,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.008,-4.779,3.771,4.98881,,,,,10.4525,,,,HOH,-1.293,0.0758425,0.00103462,0.201906 beta-lactamase_S240K,beta-lactamase_240,TEM-1,beta-lactamase,P62593,0.201922,NO,240,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.537,-3.481,1.944,4.75024,,,B,0.74,-0.74,0.357,,65.38,OPB,-1.263,0.221079,0.00591201,0.201922 kka2_1:1_P45Y,kka2_1:1_45,Kka2,kka2_1:1,P00552,0.201961,NO,45,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.774,-4.485,2.711,,0.669,.,B,0.52,-0.76,4.882,,71.59,BOH,-2.152,0.520039,0.00590481,0.201961 kka2_1:8_T187D,kka2_1:8_187,Kka2,kka2_1:8,P00552,0.201978,NO,187,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.273,-3.709,2.436,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.100394,0.00693073,0.201978 kka2_1:8_T187D,kka2_1:8_187,Kka2,kka2_1:8,P00552,0.201978,NO,187,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.273,-3.709,2.436,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.100394,0.00693073,0.201978 beta-lactamase_2500_V259N,beta-lactamase_2500_259,TEM-1,beta-lactamase_2500,P62593,0.202002,NO,259,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.361275,0.0070773,0.202002 beta-lactamase_W286T,beta-lactamase_286,TEM-1,beta-lactamase,P62593,0.202022,NO,286,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-1.111,-3.464,2.353,6.64456,0.492,,?,0.01,0.6,,,,BHX,-1.478,0.221079,,0.202022 beta-lactamase_625_D155R,beta-lactamase_625_155,TEM-1,beta-lactamase_625,P62593,0.202053,NO,155,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.889,-3.873,2.984,,0.049,,B,0.75,-0.9,4.922,,64.69,OAB,-1.62267,0.213352,0.00135315,0.202053 beta-lactamase_625_S68Q,beta-lactamase_625_68,TEM-1,beta-lactamase_625,P62593,0.202065,NO,68,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-0.913,-3.7,2.787,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.213352,0.000800065,0.202065 kka2_1:1_E231W,kka2_1:1_231,Kka2,kka2_1:1,P00552,0.202072,NO,231,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.002,-5.602,3.6,,0.503,H,A,1.04,-0.23,25.629,25.629,63.26,AAH,-2.06267,0.520039,0.00732383,0.202072 beta-lactamase_2500_E119W,beta-lactamase_2500_119,TEM-1,beta-lactamase_2500,P62593,0.202146,NO,119,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.412,-5.452,4.04,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.361275,0.00386966,0.202146 kka2_1:2_A78Y,kka2_1:2_78,Kka2,kka2_1:2,P00552,0.202183,NO,78,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.744,-4.391,2.647,,0.078,.,B,0.46,-0.53,0.206,,56.06,OHH,-1.863,0.295029,0.00457299,0.202183 kka2_1:1_V113E,kka2_1:1_113,Kka2,kka2_1:1,P00552,0.202219,NO,113,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.233,-3.887,2.654,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.520039,0.00650191,0.202219 beta-lactamase_2500_G43C,beta-lactamase_2500_43,TEM-1,beta-lactamase_2500,P62593,0.202262,NO,43,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.62,-5.087,4.467,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.361275,0.00120151,0.202262 kka2_1:4_F263Q,kka2_1:4_263,Kka2,kka2_1:4,P00552,0.202295,NO,263,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-0.911,-4.376,3.465,,0.006,G,A,0.58,-0.12,2.284,,45.83,AHH,-0.92,0.168804,0.0172454,0.202295 kka2_1:4_D208V,kka2_1:4_208,Kka2,kka2_1:4,P00552,0.202297,NO,208,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.708,-3.782,3.074,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.168804,0.00212588,0.202297 beta-lactamase_625_L218R,beta-lactamase_625_218,TEM-1,beta-lactamase_625,P62593,0.202332,NO,218,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.391,-2.276,0.885,,,I,b,0.55,-0.53,17.202,17.202,74.48,OHH,-1.58867,0.213352,0.00618274,0.202332 kka2_1:8_E63N,kka2_1:8_63,Kka2,kka2_1:8,P00552,0.202351,NO,63,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-0.762,-3.476,2.714,,0.043,H,A,1.52,-0.43,,,,AAH,-1.283,0.100394,0.00118399,0.202351 kka2_1:8_E63N,kka2_1:8_63,Kka2,kka2_1:8,P00552,0.202351,NO,63,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-0.762,-3.476,2.714,,0.043,H,A,1.52,-0.43,,,,AAH,-1.283,0.100394,0.00118399,0.202351 kka2_1:1_A215L,kka2_1:1_215,Kka2,kka2_1:1,P00552,0.202363,NO,215,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.968,-3.296,2.328,,0.039,E,B,0.46,-0.59,0.754,,50.38,HHA,-1.00467,0.520039,0.00529129,0.202363 beta-lactamase_156_L150K,beta-lactamase_156_150,TEM-1,beta-lactamase_156,P62593,0.202402,NO,150,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.326,-3.711,2.385,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.111618,0.00463171,0.202402 beta-lactamase_625_Y95N,beta-lactamase_625_95,TEM-1,beta-lactamase_625,P62593,0.202461,NO,95,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-1.715,-4.149,2.434,,0.122,,b,0.21,-0.37,3.355,,77.62,BHP,-2.16167,0.213352,0.00479449,0.202461 beta-lactamase_39_D129R,beta-lactamase_39_129,TEM-1,beta-lactamase_39,P62593,0.202478,NO,129,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.816,-3.896,3.08,,,,B,0.75,-0.69,0.56,,34.97,PAP,-0.818,0.0495842,0.00109178,0.202478 kka2_1:1_Q252W,kka2_1:1_252,Kka2,kka2_1:1,P00552,0.202492,NO,252,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.63,-5.559,2.929,,0.906,H,A,0.64,0.35,1.369,,92.05,PPB,-2.20733,0.520039,0.0121001,0.202492 kka2_1:2_I221K,kka2_1:2_221,Kka2,kka2_1:2,P00552,0.202521,NO,221,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.739,-3.896,2.157,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.295029,0.00945908,0.202521 beta-lactamase_2500_M115H,beta-lactamase_2500_115,TEM-1,beta-lactamase_2500,P62593,0.202528,NO,115,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.389,-4.759,3.37,,0.019,E,B,0.55,0.08,3.261,,69.58,OHP,-1.25433,0.361275,0.0034337,0.202528 beta-lactamase_G43T,beta-lactamase_43,TEM-1,beta-lactamase,P62593,0.202587,NO,43,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.62,-3.646,3.026,5.28886,,E,B,0.77,-0.78,,,,HOH,-1.577,0.221079,0.00120151,0.202587 beta-lactamase_156_F64E,beta-lactamase_156_64,TEM-1,beta-lactamase_156,P62593,0.202609,NO,64,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-0.841,-3.89,3.049,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.111618,0.000947691,0.202609 beta-lactamase_625_Y44D,beta-lactamase_625_44,TEM-1,beta-lactamase_625,P62593,0.202642,NO,44,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-2.547,-4.061,1.514,,,E,B,0.21,-0.45,2.371,,73.78,OHH,-1.86267,0.213352,0.00426364,0.202642 beta-lactamase_2500_G114I,beta-lactamase_2500_114,TEM-1,beta-lactamase_2500,P62593,0.202668,NO,114,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.094,-4.083,2.989,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.361275,0.00224919,0.202668 kka2_1:2_S105H,kka2_1:2_105,Kka2,kka2_1:2,P00552,0.202678,NO,105,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.945,-4.83,2.885,,0.056,S,B,0.27,-1.04,3.442,,65.53,PPB,-2.17033,0.295029,0.00847233,0.202678 beta-lactamase_625_C121Y,beta-lactamase_625_121,TEM-1,beta-lactamase_625,P62593,0.202714,NO,121,C,Y,CY,Special,Hydrophobic,5.07,5.66,0.59,194,121,181,60,108.5,193.6,85.1,-0.953,-4.188,3.235,,,H,A,0.46,-0.81,1.143,,63.29,HOP,-1.46767,0.213352,0.000744322,0.202714 beta-lactamase_2500_T158P,beta-lactamase_2500_158,TEM-1,beta-lactamase_2500,P62593,0.202747,NO,158,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.116,-2.676,1.56,,0.036,,B,0.22,-0.85,1.344,,69.58,HPB,-1.269,0.361275,0.00341825,0.202747 beta-lactamase_156_M66D,beta-lactamase_156_66,TEM-1,beta-lactamase_156,P62593,0.202759,NO,66,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.362,-4.069,2.707,,0.013,,A,0.55,-0.7,1.94,,73.08,OHH,-1.49567,0.111618,0.00412876,0.202759 kka2_1:2_G205Y,kka2_1:2_205,Kka2,kka2_1:2,P00552,0.202788,NO,205,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.596,-4.416,3.82,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.295029,0.00221855,0.202788 beta-lactamase_2500_A132N,beta-lactamase_2500_132,TEM-1,beta-lactamase_2500,P62593,0.202802,NO,132,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.9,-3.872,2.972,,,H,A,0.46,-0.93,8.408,,64.69,PHH,-1.138,0.361275,0.000962524,0.202802 kka2_1:2_R239P,kka2_1:2_239,Kka2,kka2_1:2,P00552,0.202813,NO,239,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.949,-1.624,-1.325,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.295029,0.00835326,0.202813 beta-lactamase_2500_L167W,beta-lactamase_2500_167,TEM-1,beta-lactamase_2500,P62593,0.202945,NO,167,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.138,-5.22,4.082,,0.015,G,A,0.55,-0.63,7.813,,64.69,AHP,-1.30767,0.361275,0.00303566,0.202945 kka2_1:1_M197F,kka2_1:1_197,Kka2,kka2_1:1,P00552,0.20297,NO,197,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.707,-3.862,2.155,,0.121,E,B,1.59,-1.19,2.097,,65.53,HHH,-1.847,0.520039,0.00921295,0.20297 kka2_1:1_F203H,kka2_1:1_203,Kka2,kka2_1:1,P00552,0.202998,NO,203,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-0.911,-4.571,3.66,,0.26,E,B,0.58,-0.92,7.323,,63.64,BHP,-1.34167,0.520039,0.00318738,0.202998 kka2_1:1_R177P,kka2_1:1_177,Kka2,kka2_1:1,P00552,0.203017,NO,177,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.282,-4.106,1.824,,0.521,T,A,1.2,0.16,1.842,,63.64,HBH,-2.36967,0.520039,0.00768224,0.203017 beta-lactamase_156_I261H,beta-lactamase_156_261,TEM-1,beta-lactamase_156,P62593,0.203028,NO,261,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.111618,0.0123091,0.203028 beta-lactamase_625_G249C,beta-lactamase_625_249,TEM-1,beta-lactamase_625,P62593,0.203053,NO,249,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.213352,0.00220169,0.203053 beta-lactamase_156_A185D,beta-lactamase_156_185,TEM-1,beta-lactamase_156,P62593,0.203065,NO,185,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.406,-3.867,2.461,,,H,A,0.46,-1.02,0.365,,65.03,HHP,-1.84033,0.111618,0.00467449,0.203065 beta-lactamase_L47D,beta-lactamase_47,TEM-1,beta-lactamase,P62593,0.203072,NO,47,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.876,-3.931,2.055,5.27297,0.007,E,B,1.07,0.2,1.244,,67.83,AHA,-1.639,0.221079,0.00439844,0.203072 kka2_1:8_C77I,kka2_1:8_77,Kka2,kka2_1:8,P00552,0.203096,NO,77,C,I,CI,Special,Hydrophobic,5.07,6.02,0.95,198,121,131,10,108.5,166.7,58.2,-1.477,-3.673,2.196,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.100394,0.00441216,0.203096 kka2_1:8_C77I,kka2_1:8_77,Kka2,kka2_1:8,P00552,0.203096,NO,77,C,I,CI,Special,Hydrophobic,5.07,6.02,0.95,198,121,131,10,108.5,166.7,58.2,-1.477,-3.673,2.196,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.100394,0.00441216,0.203096 kka2_1:8_R226N,kka2_1:8_226,Kka2,kka2_1:8,P00552,0.203096,NO,226,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.392,-3.682,2.29,,0.222,H,A,0.16,-0.71,3.818,,56.06,PBA,-1.84767,0.100394,0.0108032,0.203096 kka2_1:8_R226N,kka2_1:8_226,Kka2,kka2_1:8,P00552,0.203096,NO,226,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.392,-3.682,2.29,,0.222,H,A,0.16,-0.71,3.818,,56.06,PBA,-1.84767,0.100394,0.0108032,0.203096 kka2_1:1_A229M,kka2_1:1_229,Kka2,kka2_1:1,P00552,0.203102,NO,229,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.739,-4.743,3.004,,0.32,H,A,0.46,-0.7,6.549,,63.64,HHA,-1.851,0.520039,0.00942138,0.203102 kka2_1:4_G233P,kka2_1:4_233,Kka2,kka2_1:4,P00552,0.203113,NO,233,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.748,-3.907,3.159,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.168804,0.00232366,0.203113 beta-lactamase_0_T126E,beta-lactamase_0_126,TEM-1,beta-lactamase_0,P62593,0.20314,NO,126,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.122,-3.395,2.273,,0.05,H,A,0.22,-0.05,0.705,,44.41,HPH,-1.60467,0.0500837,0.00244552,0.20314 kka2_1:1_W236T,kka2_1:1_236,Kka2,kka2_1:1,P00552,0.203174,NO,236,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-1.363,-3.713,2.35,,0.303,H,A,1.51,-0.76,12.263,12.263,48.48,AHH,-1.81267,0.520039,0.0088796,0.203174 kka2_1:1_E262H,kka2_1:1_262,Kka2,kka2_1:1,P00552,0.203198,NO,262,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-0.829,-4.282,3.453,,0.059,G,A,1.04,-0.18,0.837,,42.42,AAH,-0.816,0.520039,0.0191586,0.203198 kka2_1:1_E199W,kka2_1:1_199,Kka2,kka2_1:1,P00552,0.203207,NO,199,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.234,-3.699,1.465,,0.508,E,B,1.04,-0.43,3.012,,65.53,HAP,-2.133,0.520039,0.00854122,0.203207 beta-lactamase_2500_V72H,beta-lactamase_2500_72,TEM-1,beta-lactamase_2500,P62593,0.203208,NO,72,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.658,-4.908,3.25,,,H,A,0.44,-1.03,2.079,,65.73,BHH,-1.32167,0.361275,0.00501194,0.203208 beta-lactamase_2500_T107P,beta-lactamase_2500_107,TEM-1,beta-lactamase_2500,P62593,0.20322,NO,107,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.117,-3.706,2.589,,,G,A,0.22,-0.06,2.686,,67.83,HPA,-1.265,0.361275,0.00239347,0.20322 kka2_1:1_F203A,kka2_1:1_203,Kka2,kka2_1:1,P00552,0.203223,NO,203,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-0.911,-3.329,2.418,,0.26,E,B,0.58,-0.92,7.323,,63.64,BHP,-1.34167,0.520039,0.00318738,0.203223 beta-lactamase_V42G,beta-lactamase_42,TEM-1,beta-lactamase,P62593,0.203273,NO,42,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.564,-2.773,1.209,5.27904,0.017,E,B,1.64,-0.51,2.024,,63.99,BHO,-1.042,0.221079,0.00404515,0.203273 beta-lactamase_G236L,beta-lactamase_236,TEM-1,beta-lactamase,P62593,0.2033,NO,236,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.784,-3.712,2.928,4.7915,0.241,,b,0.23,-0.59,1.883,,64.69,HOA,-1.36933,0.221079,0.00162372,0.2033 kka2_1:1_I228W,kka2_1:1_228,Kka2,kka2_1:1,P00552,0.203351,NO,228,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.142,-5.373,4.231,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.520039,0.00458834,0.203351 beta-lactamase_2500_F70R,beta-lactamase_2500_70,TEM-1,beta-lactamase_2500,P62593,0.203373,NO,70,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.169,-4.114,2.945,,,H,A,0.58,-1.34,1.918,,63.99,PHB,-0.980667,0.361275,0.00193499,0.203373 kka2_1:1_S32E,kka2_1:1_32,Kka2,kka2_1:1,P00552,0.20345,NO,32,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-0.804,-3.243,2.439,,0.768,S,b,0.27,3.75,,,,OPA,-1.74533,0.520039,0.00149998,0.20345 kka2_1:1_G55W,kka2_1:1_55,Kka2,kka2_1:1,P00552,0.203487,NO,55,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.625,-5.446,3.821,,0.517,S,b,0.29,1.19,4.035,,63.64,POH,-2.05967,0.520039,0.00667877,0.203487 beta-lactamase_625_E164L,beta-lactamase_625_164,TEM-1,beta-lactamase_625,P62593,0.203488,NO,164,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-0.948,-3.627,2.679,,0.011,T,B,1.04,-0.4,1.321,,64.69,HAO,-1.388,0.213352,0.00137286,0.203488 kka2_1:4_L19G,kka2_1:4_19,Kka2,kka2_1:4,P00552,0.20352,NO,19,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.254,-3.863,2.609,,0.08,T,A,1.59,-0.26,2.645,,65.53,BHH,-2.221,0.168804,0.00620703,0.20352 kka2_1:4_A144Y,kka2_1:4_144,Kka2,kka2_1:4,P00552,0.203545,NO,144,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.859,-4.19,3.331,,,H,A,0.46,0.21,6.844,,52.65,BHB,-1.72933,0.168804,0.00231095,0.203545 kka2_1:2_A117P,kka2_1:2_117,Kka2,kka2_1:2,P00552,0.203565,NO,117,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.828,-3.747,2.919,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.295029,0.00282984,0.203565 beta-lactamase_2500_G114M,beta-lactamase_2500_114,TEM-1,beta-lactamase_2500,P62593,0.203566,NO,114,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.094,-4.83,3.736,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.361275,0.00224919,0.203566 kka2_1:2_N195W,kka2_1:2_195,Kka2,kka2_1:2,P00552,0.203703,NO,195,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-0.836,-5.599,4.763,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.295029,0.00276134,0.203703 beta-lactamase_M115D,beta-lactamase_115,TEM-1,beta-lactamase,P62593,0.203724,NO,115,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.389,-4.023,2.634,4.89743,0.019,E,B,1.3,0.08,1.236,,69.58,OHP,-1.25433,0.221079,0.0034337,0.203724 kka2_1:1_E182S,kka2_1:1_182,Kka2,kka2_1:1,P00552,0.203738,NO,182,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.516,-3.382,1.866,,0.326,,B,1.52,0.75,14.547,14.547,65.53,OAA,-1.806,0.520039,0.00641548,0.203738 kka2_1:2_L47G,kka2_1:2_47,Kka2,kka2_1:2,P00552,0.203753,NO,47,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.265,-3.713,2.448,,0.139,E,B,0.55,-0.86,2.369,,63.26,HHH,-1.77933,0.295029,0.00509386,0.203753 kka2_1:1_M197A,kka2_1:1_197,Kka2,kka2_1:1,P00552,0.203794,NO,197,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.707,-3.22,1.513,,0.121,E,B,1.59,-1.19,2.097,,65.53,HHH,-1.847,0.520039,0.00921295,0.203794 kka2_1:1_W236D,kka2_1:1_236,Kka2,kka2_1:1,P00552,0.20381,NO,236,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-1.363,-4.158,2.795,,0.303,H,A,1.51,-0.76,12.263,12.263,48.48,AHH,-1.81267,0.520039,0.0088796,0.20381 beta-lactamase_625_I280Q,beta-lactamase_625_280,TEM-1,beta-lactamase_625,P62593,0.203841,NO,280,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.213352,0.0530888,0.203841 beta-lactamase_39_K71N,beta-lactamase_39_71,TEM-1,beta-lactamase_39,P62593,0.203864,NO,71,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-0.8,-3.448,2.648,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.0495842,0.00103192,0.203864 beta-lactamase_0_V117C,beta-lactamase_0_117,TEM-1,beta-lactamase_0,P62593,0.203909,NO,117,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.53,-4.787,3.257,,,H,A,0.44,-0.34,1.16,,65.03,PHB,-1.741,0.0500837,0.00467906,0.203909 beta-lactamase_625_D155A,beta-lactamase_625_155,TEM-1,beta-lactamase_625,P62593,0.203928,NO,155,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.889,-3.327,2.438,,0.049,,B,0.75,-0.9,4.922,,64.69,OAB,-1.62267,0.213352,0.00135315,0.203928 beta-lactamase_2500_I280R,beta-lactamase_2500_280,TEM-1,beta-lactamase_2500,P62593,0.204016,NO,280,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.361275,0.0530888,0.204016 kka2_1:1_F171E,kka2_1:1_171,Kka2,kka2_1:1,P00552,0.204087,NO,171,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.326,-3.96,2.634,,0.154,H,A,1.62,-0.1,13.679,13.679,63.64,HHH,-1.45433,0.520039,0.00821426,0.204087 beta-lactamase_2500_R220D,beta-lactamase_2500_220,TEM-1,beta-lactamase_2500,P62593,0.204124,NO,220,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-0.942,-3.72,2.778,,0.295,I,A,1.2,-0.76,2.175,,74.48,HBP,-1.33633,0.361275,0.00232421,0.204124 beta-lactamase_2500_L120E,beta-lactamase_2500_120,TEM-1,beta-lactamase_2500,P62593,0.204151,NO,120,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.044,-3.83,2.786,,,H,A,0.55,-1.13,2.48,,64.69,AHO,-1.13633,0.361275,0.00143563,0.204151 kka2_1:4_F264Q,kka2_1:4_264,Kka2,kka2_1:4,P00552,0.204155,NO,264,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.02,-4.325,3.305,,0.296,,?,1.62,0.02,1.93,,71.59,HHO,-0.9655,0.168804,,0.204155 kka2_1:4_V153K,kka2_1:4_153,Kka2,kka2_1:4,P00552,0.204179,NO,153,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.092,-3.83,2.738,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.168804,0.00501119,0.204179 beta-lactamase_2500_D231W,beta-lactamase_2500_231,TEM-1,beta-lactamase_2500,P62593,0.20421,NO,231,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.816,-5.545,4.729,,,E,B,0.75,-1.06,0.319,,65.38,HAB,-0.994,0.361275,0.00107395,0.20421 kka2_1:8_V113K,kka2_1:8_113,Kka2,kka2_1:8,P00552,0.204211,NO,113,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.233,-3.874,2.641,,0.008,H,A,1.48,-1.17,1.254,,52.27,BHP,-2.08367,0.100394,0.00650191,0.204211 kka2_1:8_V113K,kka2_1:8_113,Kka2,kka2_1:8,P00552,0.204211,NO,113,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.233,-3.874,2.641,,0.008,H,A,1.48,-1.17,1.254,,52.27,BHP,-2.08367,0.100394,0.00650191,0.204211 beta-lactamase_2500_D83C,beta-lactamase_2500_83,TEM-1,beta-lactamase_2500,P62593,0.204248,NO,83,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.066,-5.147,4.081,,0.354,H,A,0.75,0.22,0.239,,48.95,HAH,-1.34733,0.361275,0.00205968,0.204248 beta-lactamase_V42Q,beta-lactamase_42,TEM-1,beta-lactamase,P62593,0.204249,NO,42,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.564,-4.229,2.665,5.27904,0.017,E,B,1.64,-0.51,2.024,,63.99,BHO,-1.042,0.221079,0.00404515,0.204249 kka2_1:4_I228C,kka2_1:4_228,Kka2,kka2_1:4,P00552,0.204323,NO,228,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.142,-4.738,3.596,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.168804,0.00458834,0.204323 kka2_1:2_A224F,kka2_1:2_224,Kka2,kka2_1:2,P00552,0.204368,NO,224,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.977,-4.161,3.184,,,H,A,0.46,-1.26,1.646,,63.64,HHP,-1.41033,0.295029,0.00352047,0.204368 beta-lactamase_156_L160K,beta-lactamase_156_160,TEM-1,beta-lactamase_156,P62593,0.204387,NO,160,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.977,-3.757,2.78,,0.022,,B,0.55,-0.6,1.095,,44.41,BHA,-0.936,0.111618,0.00193775,0.204387 kka2_1:1_G213E,kka2_1:1_213,Kka2,kka2_1:1,P00552,0.204436,NO,213,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.596,-3.693,3.097,,,E,b,0.29,-0.4,,,,HOH,-0.920333,0.520039,0.00187654,0.204436 kka2_1:1_L102Y,kka2_1:1_102,Kka2,kka2_1:1,P00552,0.204436,NO,102,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.804,-3.989,3.185,,,T,A,0.55,-1.17,4.258,,42.42,AHH,-1.398,0.520039,0.00201332,0.204436 kka2_1:1_L184A,kka2_1:1_184,Kka2,kka2_1:1,P00552,0.204535,NO,184,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.496,-2.814,1.318,,0.489,E,B,0.55,-0.06,19.127,19.127,63.26,AHH,-1.24833,0.520039,0.00518742,0.204535 beta-lactamase_L79H,beta-lactamase_79,TEM-1,beta-lactamase,P62593,0.204563,NO,79,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.842,-4.903,4.061,4.98681,0.007,H,A,1.07,-0.16,0.823,,50.35,HHP,-1.44333,0.221079,0.000947397,0.204563 beta-lactamase_T179I,beta-lactamase_179,TEM-1,beta-lactamase,P62593,0.204666,NO,179,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.085,-3.69,2.605,5.07116,,E,B,0.8,-1.38,1.859,,73.08,PPH,-1.557,0.221079,0.00226045,0.204666 beta-lactamase_625_V31P,beta-lactamase_625_31,TEM-1,beta-lactamase_625,P62593,0.204669,NO,31,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.822,-4.128,2.306,,,H,A,0.44,-0.46,2.576,,73.78,BHB,-2.03767,0.213352,0.00478065,0.204669 kka2_1:1_F133D,kka2_1:1_133,Kka2,kka2_1:1,P00552,0.204703,NO,133,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-0.871,-3.97,3.099,,0.178,.,B,0.58,0.43,1.999,,42.42,OHA,-0.871667,0.520039,0.00182168,0.204703 kka2_1:1_S204D,kka2_1:1_204,Kka2,kka2_1:1,P00552,0.204709,NO,204,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.353,-3.549,2.196,,0.144,E,A,0.27,-1.2,3.022,,65.53,HPO,-0.953333,0.520039,0.00881794,0.204709 beta-lactamase_39_G234V,beta-lactamase_39_234,TEM-1,beta-lactamase_39,P62593,0.20471,NO,234,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.62,-3.754,3.134,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.0495842,0.000889577,0.20471 kka2_1:1_E96D,kka2_1:1_96,Kka2,kka2_1:1,P00552,0.204735,NO,96,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.573,-3.69,1.117,,0.476,,B,1.52,-0.65,1.254,,71.59,OAH,-2.143,0.520039,0.00369441,0.204735 beta-lactamase_625_D129H,beta-lactamase_625_129,TEM-1,beta-lactamase_625,P62593,0.204736,NO,129,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.816,-4.453,3.637,,,,B,0.75,-0.69,0.171,,34.97,PAP,-0.818,0.213352,0.00109178,0.204736 kka2_1:4_L260E,kka2_1:4_260,Kka2,kka2_1:4,P00552,0.204778,NO,260,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.741,-3.918,3.177,,0.022,H,A,0.55,-0.52,,,,HHA,-0.845667,0.168804,0.0233782,0.204778 kka2_1:2_K112W,kka2_1:2_112,Kka2,kka2_1:2,P00552,0.204783,NO,112,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-2.491,-5.516,3.025,,0.076,H,A,2.34,-1.37,23.433,23.433,56.06,ABH,-2.00133,0.295029,0.00645389,0.204783 kka2_1:2_V185M,kka2_1:2_185,Kka2,kka2_1:2,P00552,0.204785,NO,185,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.045,-3.067,2.022,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.295029,0.00367031,0.204785 kka2_1:2_E262L,kka2_1:2_262,Kka2,kka2_1:2,P00552,0.20485,NO,262,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-0.829,-3.61,2.781,,0.059,G,A,1.04,-0.18,2.383,,42.42,AAH,-0.816,0.295029,0.0191586,0.20485 kka2_1:1_V113N,kka2_1:1_113,Kka2,kka2_1:1,P00552,0.204901,NO,113,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.233,-4.251,3.018,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.520039,0.00650191,0.204901 beta-lactamase_2500_I244P,beta-lactamase_2500_244,TEM-1,beta-lactamase_2500,P62593,0.204911,NO,244,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.555,-4.01,2.455,,,E,B,0.48,-0.84,1.683,,77.62,OHH,-1.385,0.361275,0.00605379,0.204911 Pab1_G169R,Pab1_169,Pab1,Pab1,P04147,0.204911,NO,169,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.809,-3.75,2.941,,,E,b,0.35,0.03,,,,HOH,-1.11567,0.175299,0.000302434,0.204911 kka2_1:2_T225E,kka2_1:2_225,Kka2,kka2_1:2,P00552,0.204927,NO,225,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.393,-3.79,1.397,,0.036,H,A,0.22,-1.22,4.554,,63.64,HPB,-1.58733,0.295029,0.0113598,0.204927 kka2_1:4_D190M,kka2_1:4_190,Kka2,kka2_1:4,P00552,0.20495,NO,190,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.708,-4.958,4.25,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.168804,0.00247989,0.20495 kka2_1:8_C77Q,kka2_1:8_77,Kka2,kka2_1:8,P00552,0.204952,NO,77,C,Q,CQ,Special,Polar,5.07,6.24429,1.17429,154,121,146,25,108.5,143.8,35.3,-1.477,-4.277,2.8,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.100394,0.00441216,0.204952 kka2_1:8_C77Q,kka2_1:8_77,Kka2,kka2_1:8,P00552,0.204952,NO,77,C,Q,CQ,Special,Polar,5.07,6.24429,1.17429,154,121,146,25,108.5,143.8,35.3,-1.477,-4.277,2.8,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.100394,0.00441216,0.204952 beta-lactamase_156_V259P,beta-lactamase_156_259,TEM-1,beta-lactamase_156,P62593,0.204959,NO,259,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.111618,0.0070773,0.204959 beta-lactamase_I229D,beta-lactamase_229,TEM-1,beta-lactamase,P62593,0.204977,NO,229,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.267,-3.973,2.706,5.0911,0.083,E,B,1,-0.76,1.114,,50,HHH,-1.58767,0.221079,0.00477249,0.204977 kka2_1:1_F37D,kka2_1:1_37,Kka2,kka2_1:1,P00552,0.204986,NO,37,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.427,-4.022,2.595,,0.219,E,B,0.58,-0.25,18.64,18.64,64.39,HHB,-1.17733,0.520039,0.00586193,0.204986 beta-lactamase_625_V72R,beta-lactamase_625_72,TEM-1,beta-lactamase_625,P62593,0.205,NO,72,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.658,-4.097,2.439,,,H,A,0.44,-1.03,0.981,,65.73,BHH,-1.32167,0.213352,0.00501194,0.205 beta-lactamase_2500_V72N,beta-lactamase_2500_72,TEM-1,beta-lactamase_2500,P62593,0.205013,NO,72,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.658,-4.143,2.485,,,H,A,0.44,-1.03,2.079,,65.73,BHH,-1.32167,0.361275,0.00501194,0.205013 beta-lactamase_2500_G236C,beta-lactamase_2500_236,TEM-1,beta-lactamase_2500,P62593,0.205049,NO,236,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.784,-4.991,4.207,,0.241,,b,0.29,-0.59,2.14,,64.69,HOO,-1.025,0.361275,0.00162372,0.205049 beta-lactamase_2500_Y262H,beta-lactamase_2500_262,TEM-1,beta-lactamase_2500,P62593,0.205145,NO,262,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.361275,0.00853516,0.205145 beta-lactamase_2500_I229N,beta-lactamase_2500_229,TEM-1,beta-lactamase_2500,P62593,0.205159,NO,229,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.267,-4.128,2.861,,0.083,E,B,0.48,-0.76,3.875,,50,HHH,-1.58767,0.361275,0.00477249,0.205159 kka2_1:2_F48R,kka2_1:2_48,Kka2,kka2_1:2,P00552,0.205195,NO,48,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.453,-4.265,2.812,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.295029,0.00475422,0.205195 beta-lactamase_M209V,beta-lactamase_209,TEM-1,beta-lactamase,P62593,0.205204,NO,209,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.442,-2.446,1.004,5.44502,,H,A,1.75,-0.97,1.402,,64.69,HHA,-1.52633,0.221079,0.00625021,0.205204 beta-lactamase_T107W,beta-lactamase_107,TEM-1,beta-lactamase,P62593,0.205204,NO,107,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.117,-5.223,4.106,5.23432,,G,A,2.12,-0.06,3.676,,67.83,HPA,-1.265,0.221079,0.00239347,0.205204 kka2_1:2_R226I,kka2_1:2_226,Kka2,kka2_1:2,P00552,0.205208,NO,226,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.392,-4.182,2.79,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.295029,0.0108032,0.205208 kka2_1:2_R66K,kka2_1:2_66,Kka2,kka2_1:2,P00552,0.205234,NO,66,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-0.922,-2.125,1.203,,0.103,H,A,1.2,-0.2,2.659,,46.21,HBH,-1.13567,0.295029,0.00161025,0.205234 kka2_1:2_R66V,kka2_1:2_66,Kka2,kka2_1:2,P00552,0.205234,NO,66,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-0.922,-3.78,2.858,,0.103,H,A,1.2,-0.2,2.659,,46.21,HBH,-1.13567,0.295029,0.00161025,0.205234 kka2_1:1_L232N,kka2_1:1_232,Kka2,kka2_1:1,P00552,0.205263,NO,232,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.514,-4.176,2.662,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.520039,0.00800103,0.205263 kka2_1:4_R211Q,kka2_1:4_211,Kka2,kka2_1:4,P00552,0.205292,NO,211,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-0.899,-3.552,2.653,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.168804,0.00204888,0.205292 kka2_1:2_P76V,kka2_1:2_76,Kka2,kka2_1:2,P00552,0.205389,NO,76,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.449,-2.929,1.48,,0.331,.,B,0.52,-0.41,0.345,,63.64,HOO,-1.662,0.295029,0.00625685,0.205389 beta-lactamase_156_A133Y,beta-lactamase_156_133,TEM-1,beta-lactamase_156,P62593,0.205436,NO,133,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.186,-4.319,3.133,,,H,A,0.46,-0.86,0.805,,67.83,HHP,-0.988333,0.111618,0.00468022,0.205436 kka2_1:2_D261N,kka2_1:2_261,Kka2,kka2_1:2,P00552,0.205441,NO,261,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.708,-3.251,2.543,,0.146,G,A,0.75,-0.33,,,,HAA,-0.759333,0.295029,0.0224846,0.205441 beta-lactamase_39_M209P,beta-lactamase_39_209,TEM-1,beta-lactamase_39,P62593,0.205456,NO,209,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.442,-4.077,2.635,,,H,A,0.55,-0.97,1.167,,64.69,HHA,-1.52633,0.0495842,0.00625021,0.205456 beta-lactamase_156_L188D,beta-lactamase_156_188,TEM-1,beta-lactamase_156,P62593,0.205473,NO,188,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.166,-3.967,2.801,,,H,A,0.55,-0.3,1.574,,60.14,PHB,-1.47033,0.111618,0.00295687,0.205473 kka2_1:1_F203D,kka2_1:1_203,Kka2,kka2_1:1,P00552,0.205474,NO,203,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-0.911,-4.011,3.1,,0.26,E,B,0.58,-0.92,7.323,,63.64,BHP,-1.34167,0.520039,0.00318738,0.205474 kka2_1:1_L102E,kka2_1:1_102,Kka2,kka2_1:1,P00552,0.205481,NO,102,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.804,-3.916,3.112,,,T,A,0.55,-1.17,4.258,,42.42,AHH,-1.398,0.520039,0.00201332,0.205481 kka2_1:1_L241W,kka2_1:1_241,Kka2,kka2_1:1,P00552,0.205567,NO,241,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.158,-4.909,3.751,,0.08,H,A,0.55,-0.82,1.685,,63.26,HHH,-1.58533,0.520039,0.0117299,0.205567 kka2_1:4_L93H,kka2_1:4_93,Kka2,kka2_1:4,P00552,0.205643,NO,93,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.815,-4.864,4.049,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.168804,0.00131498,0.205643 beta-lactamase_2500_I140R,beta-lactamase_2500_140,TEM-1,beta-lactamase_2500,P62593,0.205648,NO,140,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.733,-4.193,2.46,,0.128,H,A,0.48,0.41,1.628,,73.08,PHO,-1.48733,0.361275,0.00597777,0.205648 beta-lactamase_625_K32P,beta-lactamase_625_32,TEM-1,beta-lactamase_625,P62593,0.20567,NO,32,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.984,-3.947,1.963,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.213352,0.00401283,0.20567 beta-lactamase_625_M66E,beta-lactamase_625_66,TEM-1,beta-lactamase_625,P62593,0.20567,NO,66,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.362,-3.832,2.47,,0.013,,A,0.55,-0.7,1.659,,73.08,OHH,-1.49567,0.213352,0.00412876,0.20567 kka2_1:1_A237P,kka2_1:1_237,Kka2,kka2_1:1,P00552,0.205708,NO,237,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.12,-4.041,1.921,,0.068,H,A,0.46,-0.71,2.369,,92.05,HHA,-2.10433,0.520039,0.012257,0.205708 beta-lactamase_156_G249T,beta-lactamase_156_249,TEM-1,beta-lactamase_156,P62593,0.20571,NO,249,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.111618,0.00220169,0.20571 kka2_1:4_A25P,kka2_1:4_25,Kka2,kka2_1:4,P00552,0.205718,NO,25,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.496,-3.994,1.498,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.168804,0.00595636,0.205718 kka2_1:2_I207W,kka2_1:2_207,Kka2,kka2_1:2,P00552,0.205737,NO,207,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.175,-5.409,4.234,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.295029,0.00611824,0.205737 beta-lactamase_156_S241I,beta-lactamase_156_241,TEM-1,beta-lactamase_156,P62593,0.205761,NO,241,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.111618,0.00452736,0.205761 beta-lactamase_625_L150P,beta-lactamase_625_150,TEM-1,beta-lactamase_625,P62593,0.205766,NO,150,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.326,-4.037,2.711,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.213352,0.00463171,0.205766 beta-lactamase_39_V260Q,beta-lactamase_39_260,TEM-1,beta-lactamase_39,P62593,0.205938,NO,260,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.0495842,0.00471757,0.205938 beta-lactamase_39_N130Y,beta-lactamase_39_130,TEM-1,beta-lactamase_39,P62593,0.205977,NO,130,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-0.798,-4.162,3.364,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.0495842,0.000683376,0.205977 beta-lactamase_625_E164A,beta-lactamase_625_164,TEM-1,beta-lactamase_625,P62593,0.206008,NO,164,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-0.948,-3.102,2.154,,0.011,T,B,1.04,-0.4,1.321,,64.69,HAO,-1.388,0.213352,0.00137286,0.206008 beta-lactamase_625_S241R,beta-lactamase_625_241,TEM-1,beta-lactamase_625,P62593,0.206008,NO,241,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.433,-3.314,1.881,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.213352,0.00452736,0.206008 beta-lactamase_625_K71N,beta-lactamase_625_71,TEM-1,beta-lactamase_625,P62593,0.206009,NO,71,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-0.8,-3.448,2.648,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.213352,0.00103192,0.206009 kka2_1:2_L241H,kka2_1:2_241,Kka2,kka2_1:2,P00552,0.206051,NO,241,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.158,-4.825,3.667,,0.08,H,A,0.55,-0.82,1.598,,63.26,HHH,-1.58533,0.295029,0.0117299,0.206051 kka2_1:1_P12H,kka2_1:1_12,Kka2,kka2_1:1,P00552,0.206058,NO,12,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.853,-4.718,3.865,,,.,B,0.52,1.25,0.261,,48.11,POH,-1.80767,0.520039,0.00500011,0.206058 kka2_1:2_I228A,kka2_1:2_228,Kka2,kka2_1:2,P00552,0.206073,NO,228,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.142,-3.138,1.996,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.295029,0.00458834,0.206073 beta-lactamase_39_D129V,beta-lactamase_39_129,TEM-1,beta-lactamase_39,P62593,0.206082,NO,129,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.816,-3.751,2.935,,,,B,0.75,-0.69,0.56,,34.97,PAP,-0.818,0.0495842,0.00109178,0.206082 beta-lactamase_625_F58P,beta-lactamase_625_58,TEM-1,beta-lactamase_625,P62593,0.206105,NO,58,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-2.914,-4.147,1.233,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.213352,0.00523369,0.206105 kka2_1:2_V75R,kka2_1:2_75,Kka2,kka2_1:2,P00552,0.206121,NO,75,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-2.06,-4.101,2.041,,0.042,.,B,0.44,-0.2,2.815,,71.59,OHO,-1.563,0.295029,0.00693733,0.206121 kka2_1:2_L223Y,kka2_1:2_223,Kka2,kka2_1:2,P00552,0.206147,NO,223,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.861,-4.01,3.149,,,H,A,0.55,-1.24,0.266,,50,HHH,-0.854333,0.295029,0.00253574,0.206147 kka2_1:1_D156E,kka2_1:1_156,Kka2,kka2_1:1,P00552,0.206176,NO,156,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.696,-2.041,0.345,,0.884,T,A,0.75,1.87,1.044,,65.53,PAA,-1.765,0.520039,0.00926998,0.206176 kka2_1:1_G30N,kka2_1:1_30,Kka2,kka2_1:1,P00552,0.206225,NO,30,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.596,-3.476,2.88,,0.54,S,g,0.29,3.76,,,,HOO,-1.51133,0.520039,0.00159208,0.206225 beta-lactamase_L137K,beta-lactamase_137,TEM-1,beta-lactamase,P62593,0.206229,NO,137,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.03,-3.749,2.719,5.20117,,H,A,1.07,-0.38,0.674,,42.31,HHP,-1.58933,0.221079,0.00278599,0.206229 kka2_1:1_I196N,kka2_1:1_196,Kka2,kka2_1:1,P00552,0.206292,NO,196,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-2.115,-4.284,2.169,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.520039,0.0107273,0.206292 beta-lactamase_156_I261N,beta-lactamase_156_261,TEM-1,beta-lactamase_156,P62593,0.206325,NO,261,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.111618,0.0123091,0.206325 beta-lactamase_C18R,beta-lactamase_18,TEM-1,beta-lactamase,P62593,0.206351,NO,18,C,R,CR,Special,PositiveCharge,5.07,6.34148,1.27148,180,121,174,53,108.5,173.4,64.9,-2.26,-3.948,1.688,,,,,,,3.995,,93.01,HOH,-2.093,0.221079,0.002536,0.206351 kka2_1:2_Y218I,kka2_1:2_218,Kka2,kka2_1:2,P00552,0.206375,NO,218,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-1.438,-3.85,2.412,,0.122,H,A,0.21,-0.69,1.022,,56.06,BHP,-1.17533,0.295029,0.0126098,0.206375 kka2_1:2_W236N,kka2_1:2_236,Kka2,kka2_1:2,P00552,0.206387,NO,236,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-1.363,-4.289,2.926,,0.303,H,A,1.51,-0.76,5.58,,48.48,AHH,-1.81267,0.295029,0.0088796,0.206387 kka2_1:1_K138W,kka2_1:1_138,Kka2,kka2_1:1,P00552,0.206406,NO,138,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-2.5,-5.6,3.1,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.520039,0.00628542,0.206406 beta-lactamase_625_P181N,beta-lactamase_625_181,TEM-1,beta-lactamase_625,P62593,0.206426,NO,181,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.813,-3.924,3.111,,,H,A,0.52,-1.14,1.797,,61.54,HOH,-1.795,0.213352,0.000703122,0.206426 beta-lactamase_T158N,beta-lactamase_158,TEM-1,beta-lactamase,P62593,0.206516,NO,158,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.116,-3.488,2.372,5.32011,0.036,,B,0.98,-0.85,2.755,,69.58,HPB,-1.269,0.221079,0.00341825,0.206516 beta-lactamase_39_V72R,beta-lactamase_39_72,TEM-1,beta-lactamase_39,P62593,0.206521,NO,72,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.658,-4.097,2.439,,,H,A,0.44,-1.03,1.92,,65.73,BHH,-1.32167,0.0495842,0.00501194,0.206521 beta-lactamase_2500_R59P,beta-lactamase_2500_59,TEM-1,beta-lactamase_2500,P62593,0.206523,NO,59,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.345,-3.961,2.616,,0.329,S,L,1.2,-0.09,3.719,,73.08,HBO,-2.24267,0.361275,0.00318082,0.206523 beta-lactamase_156_R81P,beta-lactamase_156_81,TEM-1,beta-lactamase_156,P62593,0.206549,NO,81,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.466,-3.949,2.483,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.111618,0.00499763,0.206549 kka2_1:1_V186S,kka2_1:1_186,Kka2,kka2_1:1,P00552,0.206588,NO,186,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.011,-3.722,2.711,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.520039,0.00409703,0.206588 kka2_1:2_F264G,kka2_1:2_264,Kka2,kka2_1:2,P00552,0.206589,NO,264,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.02,-3.702,2.682,,0.296,.,?,0.58,0.02,2.303,,71.59,HHNA,-0.9655,0.295029,,0.206589 kka2_1:8_H188F,kka2_1:8_188,Kka2,kka2_1:8,P00552,0.206613,NO,188,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-0.913,-3.931,3.018,,0.006,,A,0.87,-1.02,1.241,,47.73,PBO,-0.927333,0.100394,0.00273139,0.206613 kka2_1:8_H188F,kka2_1:8_188,Kka2,kka2_1:8,P00552,0.206613,NO,188,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-0.913,-3.931,3.018,,0.006,,A,0.87,-1.02,1.241,,47.73,PBO,-0.927333,0.100394,0.00273139,0.206613 beta-lactamase_625_T179N,beta-lactamase_625_179,TEM-1,beta-lactamase_625,P62593,0.206637,NO,179,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.085,-3.487,2.402,,,E,B,0.22,-1.38,0.367,,73.08,PPH,-1.557,0.213352,0.00226045,0.206637 kka2_1:2_G213M,kka2_1:2_213,Kka2,kka2_1:2,P00552,0.206676,NO,213,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.596,-4.958,4.362,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.295029,0.00187654,0.206676 beta-lactamase_625_L160K,beta-lactamase_625_160,TEM-1,beta-lactamase_625,P62593,0.206708,NO,160,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.977,-3.757,2.78,,0.022,,B,0.55,-0.6,0.237,,44.41,BHA,-0.936,0.213352,0.00193775,0.206708 kka2_1:1_V80C,kka2_1:1_80,Kka2,kka2_1:1,P00552,0.206736,NO,80,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.144,-4.756,3.612,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.520039,0.00488211,0.206736 kka2_1:2_A222T,kka2_1:2_222,Kka2,kka2_1:2,P00552,0.206741,NO,222,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.725,-3.225,2.5,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.295029,0.00207657,0.206741 kka2_1:4_E262L,kka2_1:4_262,Kka2,kka2_1:4,P00552,0.206747,NO,262,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-0.829,-3.61,2.781,,0.059,G,A,1.04,-0.18,2.383,,42.42,AAH,-0.816,0.168804,0.0191586,0.206747 beta-lactamase_2500_T147Y,beta-lactamase_2500_147,TEM-1,beta-lactamase_2500,P62593,0.206748,NO,147,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.149,-4.243,3.094,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.361275,0.00226017,0.206748 beta-lactamase_39_A132D,beta-lactamase_39_132,TEM-1,beta-lactamase_39,P62593,0.206817,NO,132,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.9,-3.706,2.806,,,H,A,0.46,-0.93,8.408,,64.69,PHH,-1.138,0.0495842,0.000962524,0.206817 beta-lactamase_156_N130E,beta-lactamase_156_130,TEM-1,beta-lactamase_156,P62593,0.206861,NO,130,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-0.798,-3.215,2.417,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.111618,0.000683376,0.206861 beta-lactamase_G85P,beta-lactamase_85,TEM-1,beta-lactamase,P62593,0.206876,NO,85,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.011,-3.891,2.88,5.58951,0.805,T,l,0.23,1.7,1.468,,63.64,HOP,-1.68733,0.221079,0.00252173,0.206876 beta-lactamase_39_A235P,beta-lactamase_39_235,TEM-1,beta-lactamase_39,P62593,0.206901,NO,235,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.266,-3.821,2.555,,0.32,E,B,0.46,-0.86,1.344,,50,OHO,-0.89,0.0495842,0.00493474,0.206901 beta-lactamase_625_L150E,beta-lactamase_625_150,TEM-1,beta-lactamase_625,P62593,0.206926,NO,150,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.326,-3.822,2.496,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.213352,0.00463171,0.206926 kka2_1:1_G43I,kka2_1:1_43,Kka2,kka2_1:1,P00552,0.206928,NO,43,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.587,-4.201,2.614,,0.862,T,l,0.75,-0.67,2.247,,63.26,POB,-2.18533,0.520039,0.0071925,0.206928 beta-lactamase_625_S128D,beta-lactamase_625_128,TEM-1,beta-lactamase_625,P62593,0.206932,NO,128,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-0.84,-3.244,2.404,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.213352,0.00071483,0.206932 kka2_1:1_D208I,kka2_1:1_208,Kka2,kka2_1:1,P00552,0.206982,NO,208,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.708,-4.039,3.331,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.520039,0.00212588,0.206982 beta-lactamase_156_S68T,beta-lactamase_156_68,TEM-1,beta-lactamase_156,P62593,0.206994,NO,68,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-0.913,-3.02,2.107,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.111618,0.000800065,0.206994 Pab1_I130R,Pab1_130,Pab1,Pab1,P04147,0.207023,NO,130,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.212,-3.975,2.763,,,E,B,1.23,0.01,,,,HHB,-1.188,0.175299,0.000351112,0.207023 beta-lactamase_2500_S233F,beta-lactamase_2500_233,TEM-1,beta-lactamase_2500,P62593,0.207122,NO,233,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.886,-4.226,2.34,,0.016,E,B,0.27,-1.01,2.851,,77.62,BPO,-1.17267,0.361275,0.00311415,0.207122 beta-lactamase_2500_M209G,beta-lactamase_2500_209,TEM-1,beta-lactamase_2500,P62593,0.207158,NO,209,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.442,-3.732,2.29,,,H,A,0.55,-0.97,3.229,,64.69,HHA,-1.52633,0.361275,0.00625021,0.207158 kka2_1:1_V36Y,kka2_1:1_36,Kka2,kka2_1:1,P00552,0.20726,NO,36,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-0.898,-4.01,3.112,,0.292,E,B,0.44,0.21,0.278,,52.27,HHH,-1.484,0.520039,0.00245633,0.20726 beta-lactamase_2500_F58D,beta-lactamase_2500_58,TEM-1,beta-lactamase_2500,P62593,0.207312,NO,58,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-2.914,-3.846,0.932,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.361275,0.00523369,0.207312 beta-lactamase_625_G249Q,beta-lactamase_625_249,TEM-1,beta-lactamase_625,P62593,0.207319,NO,249,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.213352,0.00220169,0.207319 beta-lactamase_625_A124H,beta-lactamase_625_124,TEM-1,beta-lactamase_625,P62593,0.207332,NO,124,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.181,-4.785,3.604,,,H,A,0.46,-0.9,2.027,,64.34,HHH,-1.152,0.213352,0.00481399,0.207332 beta-lactamase_2500_A34P,beta-lactamase_2500_34,TEM-1,beta-lactamase_2500,P62593,0.207396,NO,34,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.059,-4.024,1.965,,,H,A,0.46,-0.54,2.921,,73.78,AHA,-1.74967,0.361275,0.00407913,0.207396 kka2_1:4_G99M,kka2_1:4_99,Kka2,kka2_1:4,P00552,0.207453,NO,99,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.596,-4.958,4.362,,0.368,S,g,0.29,-0.87,,,,OOP,-1.63067,0.168804,0.00186055,0.207453 kka2_1:2_G205N,kka2_1:2_205,Kka2,kka2_1:2,P00552,0.207459,NO,205,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.596,-3.476,2.88,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.295029,0.00221855,0.207459 beta-lactamase_156_S128P,beta-lactamase_156_128,TEM-1,beta-lactamase_156,P62593,0.207463,NO,128,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-0.84,-3.655,2.815,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.111618,0.00071483,0.207463 beta-lactamase_156_Y44D,beta-lactamase_156_44,TEM-1,beta-lactamase_156,P62593,0.207515,NO,44,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-2.547,-4.061,1.514,,,E,B,0.21,-0.45,2.184,,73.78,OHH,-1.86267,0.111618,0.00426364,0.207515 beta-lactamase_625_V260R,beta-lactamase_625_260,TEM-1,beta-lactamase_625,P62593,0.207527,NO,260,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.213352,0.00471757,0.207527 kka2_1:2_S32H,kka2_1:2_32,Kka2,kka2_1:2,P00552,0.207531,NO,32,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-0.804,-4.483,3.679,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.295029,0.00149998,0.207531 kka2_1:1_T187W,kka2_1:1_187,Kka2,kka2_1:1,P00552,0.207614,NO,187,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.273,-5.339,4.066,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.520039,0.00693073,0.207614 beta-lactamase_156_A230H,beta-lactamase_156_230,TEM-1,beta-lactamase_156,P62593,0.207617,NO,230,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.154,-4.737,3.583,,0.01,E,B,0.46,-1.17,2.179,,50,HHA,-1.079,0.111618,0.00516841,0.207617 kka2_1:1_H106I,kka2_1:1_106,Kka2,kka2_1:1,P00552,0.207624,NO,106,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-3.13,-4.034,0.904,,1.065,.,a,0.17,-0.95,2.53,,71.59,PBH,-2.10433,0.520039,0.00730778,0.207624 beta-lactamase_39_T69W,beta-lactamase_39_69,TEM-1,beta-lactamase_39,P62593,0.207759,NO,69,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-0.973,-5.208,4.235,,,G,A,0.22,-1.24,4.194,,93.01,PPH,-1.01833,0.0495842,0.00127498,0.207759 kka2_1:2_A215M,kka2_1:2_215,Kka2,kka2_1:2,P00552,0.207772,NO,215,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.968,-4.593,3.625,,0.039,E,B,0.46,-0.59,2.137,,50.38,HHA,-1.00467,0.295029,0.00529129,0.207772 kka2_1:1_C209I,kka2_1:1_209,Kka2,kka2_1:1,P00552,0.207792,NO,209,C,I,CI,Special,Hydrophobic,5.07,6.02,0.95,198,121,131,10,108.5,166.7,58.2,-0.906,-3.519,2.613,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.520039,0.00260862,0.207792 kka2_1:1_L102H,kka2_1:1_102,Kka2,kka2_1:1,P00552,0.207792,NO,102,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.804,-4.931,4.127,,,T,A,0.55,-1.17,4.258,,42.42,AHH,-1.398,0.520039,0.00201332,0.207792 beta-lactamase_39_C75Y,beta-lactamase_39_75,TEM-1,beta-lactamase_39,P62593,0.207805,NO,75,C,Y,CY,Special,Hydrophobic,5.07,5.66,0.59,194,121,181,60,108.5,193.6,85.1,-1.245,-4.265,3.02,,,H,A,0.46,-0.87,2.369,,50,HOO,-1.24333,0.0495842,0.0034616,0.207805 beta-lactamase_625_G249W,beta-lactamase_625_249,TEM-1,beta-lactamase_625,P62593,0.207814,NO,249,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.213352,0.00220169,0.207814 kka2_1:1_W15M,kka2_1:1_15,Kka2,kka2_1:1,P00552,0.20785,NO,15,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-1.392,-4.272,2.88,,0.01,G,A,0.47,0.15,20.149,20.149,52.27,HHH,-2.10533,0.520039,0.00585505,0.20785 beta-lactamase_2500_L120R,beta-lactamase_2500_120,TEM-1,beta-lactamase_2500,P62593,0.207891,NO,120,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.044,-2.871,1.827,,,H,A,0.55,-1.13,2.48,,64.69,AHO,-1.13633,0.361275,0.00143563,0.207891 beta-lactamase_2500_L150K,beta-lactamase_2500_150,TEM-1,beta-lactamase_2500,P62593,0.207894,NO,150,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.326,-3.711,2.385,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.361275,0.00463171,0.207894 kka2_1:1_A25M,kka2_1:1_25,Kka2,kka2_1:1,P00552,0.207954,NO,25,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.496,-3.529,1.033,,0.427,E,B,0.46,-0.47,6.872,6.872,65.53,HHP,-2.15167,0.520039,0.00595636,0.207954 kka2_1:1_A25W,kka2_1:1_25,Kka2,kka2_1:1,P00552,0.207954,NO,25,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.496,-5.529,3.033,,0.427,E,B,0.46,-0.47,6.872,6.872,65.53,HHP,-2.15167,0.520039,0.00595636,0.207954 kka2_1:8_P194F,kka2_1:8_194,Kka2,kka2_1:8,P00552,0.208083,NO,194,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.846,-4.517,3.671,,0.308,G,A,0.52,-1.19,4.861,,53.03,HOP,-0.888333,0.100394,0.00314194,0.208083 kka2_1:8_P194F,kka2_1:8_194,Kka2,kka2_1:8,P00552,0.208083,NO,194,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.846,-4.517,3.671,,0.308,G,A,0.52,-1.19,4.861,,53.03,HOP,-0.888333,0.100394,0.00314194,0.208083 kka2_1:1_P194E,kka2_1:1_194,Kka2,kka2_1:1,P00552,0.208138,NO,194,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.846,-3.407,2.561,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.520039,0.00314194,0.208138 kka2_1:2_R258V,kka2_1:2_258,Kka2,kka2_1:2,P00552,0.208161,NO,258,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.626,-3.61,1.984,,0.316,H,A,1.2,-0.85,7.485,7.485,53.03,HBH,-1.25933,0.295029,0.00983174,0.208161 beta-lactamase_39_C75W,beta-lactamase_39_75,TEM-1,beta-lactamase_39,P62593,0.208207,NO,75,C,W,CW,Special,Hydrophobic,5.07,5.89,0.82,215,121,204,83,108.5,227.8,119.3,-1.245,-5.246,4.001,,,H,A,0.46,-0.87,2.369,,50,HOO,-1.24333,0.0495842,0.0034616,0.208207 kka2_1:4_G233A,kka2_1:4_233,Kka2,kka2_1:4,P00552,0.208211,NO,233,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.748,-2.995,2.247,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.168804,0.00232366,0.208211 kka2_1:1_E86H,kka2_1:1_86,Kka2,kka2_1:1,P00552,0.208221,NO,86,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.86,-2.283,0.423,,0.369,.,B,1.04,1.92,18.506,18.506,63.26,PAH,-1.98067,0.520039,0.00642858,0.208221 kka2_1:1_R226K,kka2_1:1_226,Kka2,kka2_1:1,P00552,0.208247,NO,226,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.392,-3.285,1.893,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.520039,0.0108032,0.208247 kka2_1:4_R226P,kka2_1:4_226,Kka2,kka2_1:4,P00552,0.208262,NO,226,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.392,-4.085,2.693,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.168804,0.0108032,0.208262 beta-lactamase_2500_A40P,beta-lactamase_2500_40,TEM-1,beta-lactamase_2500,P62593,0.208276,NO,40,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.402,-3.856,2.454,,0.155,S,B,0.46,0.21,0.953,,73.78,OHB,-1.40267,0.361275,0.00490026,0.208276 beta-lactamase_2500_L146E,beta-lactamase_2500_146,TEM-1,beta-lactamase_2500,P62593,0.208277,NO,146,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.462,-3.93,2.468,,0.007,H,A,0.55,-0.56,1.578,,64.69,AHP,-1.656,0.361275,0.00474542,0.208277 beta-lactamase_39_L79P,beta-lactamase_39_79,TEM-1,beta-lactamase_39,P62593,0.208353,NO,79,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.842,-4.102,3.26,,0.007,H,A,0.55,-0.16,0.823,,50.35,HHP,-1.44333,0.0495842,0.000947397,0.208353 kka2_1:1_A224W,kka2_1:1_224,Kka2,kka2_1:1,P00552,0.208356,NO,224,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.977,-5.377,4.4,,,H,A,0.46,-1.26,1.725,,63.64,HHP,-1.41033,0.520039,0.00352047,0.208356 kka2_1:2_D216R,kka2_1:2_216,Kka2,kka2_1:2,P00552,0.208399,NO,216,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.785,-3.929,3.144,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.295029,0.00229969,0.208399 kka2_1:4_Y22I,kka2_1:4_22,Kka2,kka2_1:4,P00552,0.208447,NO,22,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-1.583,-3.083,1.5,,0.122,.,B,0.21,-0.8,1.838,,65.53,OHA,-1.80333,0.168804,0.00598977,0.208447 beta-lactamase_156_T178W,beta-lactamase_156_178,TEM-1,beta-lactamase_156,P62593,0.208469,NO,178,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-0.791,-5.097,4.306,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.111618,0.000684366,0.208469 beta-lactamase_156_A132W,beta-lactamase_156_132,TEM-1,beta-lactamase_156,P62593,0.208536,NO,132,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.9,-5.372,4.472,,,H,A,0.46,-0.93,10.621,,64.69,PHH,-1.138,0.111618,0.000962524,0.208536 beta-lactamase_2500_P165W,beta-lactamase_2500_165,TEM-1,beta-lactamase_2500,P62593,0.208623,NO,165,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.373,-5.352,3.979,,0.203,T,A,0.52,-0.31,0.414,,73.78,AOA,-1.359,0.361275,0.00549538,0.208623 kka2_1:8_H188K,kka2_1:8_188,Kka2,kka2_1:8,P00552,0.208633,NO,188,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-0.913,-3.453,2.54,,0.006,,A,0.87,-1.02,1.241,,47.73,PBO,-0.927333,0.100394,0.00273139,0.208633 kka2_1:8_H188K,kka2_1:8_188,Kka2,kka2_1:8,P00552,0.208633,NO,188,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-0.913,-3.453,2.54,,0.006,,A,0.87,-1.02,1.241,,47.73,PBO,-0.927333,0.100394,0.00273139,0.208633 kka2_1:1_W24N,kka2_1:1_24,Kka2,kka2_1:1,P00552,0.208726,NO,24,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-1.779,-4.301,2.522,,0.477,E,B,0.47,-0.21,2.375,,56.06,AHH,-2.24467,0.520039,0.00631564,0.208726 kka2_1:1_A117F,kka2_1:1_117,Kka2,kka2_1:1,P00552,0.208728,NO,117,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.828,-4.094,3.266,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.520039,0.00282984,0.208728 beta-lactamase_2500_L120Q,beta-lactamase_2500_120,TEM-1,beta-lactamase_2500,P62593,0.20876,NO,120,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.044,-4.124,3.08,,,H,A,0.55,-1.13,2.48,,64.69,AHO,-1.13633,0.361275,0.00143563,0.20876 beta-lactamase_625_M209H,beta-lactamase_625_209,TEM-1,beta-lactamase_625,P62593,0.208771,NO,209,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.442,-4.813,3.371,,,H,A,0.55,-0.97,1.167,,64.69,HHA,-1.52633,0.213352,0.00625021,0.208771 kka2_1:2_L67A,kka2_1:2_67,Kka2,kka2_1:2,P00552,0.208771,NO,67,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.741,-3.106,2.365,,0.007,H,A,1.59,-0.66,,,,BHP,-1.42867,0.295029,0.00102787,0.208771 kka2_1:8_G189K,kka2_1:8_189,Kka2,kka2_1:8,P00552,0.208816,NO,189,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.596,-3.71,3.114,,0.034,S,l,0.75,-0.99,,,,BOA,-0.739,0.100394,0.00253688,0.208816 kka2_1:8_G189K,kka2_1:8_189,Kka2,kka2_1:8,P00552,0.208816,NO,189,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.596,-3.71,3.114,,0.034,S,l,0.75,-0.99,,,,BOA,-0.739,0.100394,0.00253688,0.208816 beta-lactamase_625_W227Q,beta-lactamase_625_227,TEM-1,beta-lactamase_625,P62593,0.208822,NO,227,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-0.982,-4.194,3.212,,0.272,,B,0.47,-0.29,2.533,,74.48,OHH,-1.595,0.213352,0.00226019,0.208822 beta-lactamase_2500_Y95T,beta-lactamase_2500_95,TEM-1,beta-lactamase_2500,P62593,0.20886,NO,95,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-1.715,-3.697,1.982,,0.122,,b,0.21,-0.37,2.914,,77.62,BHP,-2.16167,0.361275,0.00479449,0.20886 beta-lactamase_156_G234H,beta-lactamase_156_234,TEM-1,beta-lactamase_156,P62593,0.208864,NO,234,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.62,-4.68,4.06,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.111618,0.000889577,0.208864 beta-lactamase_156_G234D,beta-lactamase_156_234,TEM-1,beta-lactamase_156,P62593,0.208892,NO,234,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.62,-3.469,2.849,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.111618,0.000889577,0.208892 kka2_1:1_A222L,kka2_1:1_222,Kka2,kka2_1:1,P00552,0.208916,NO,222,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.725,-3.161,2.436,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.520039,0.00207657,0.208916 kka2_1:1_V153K,kka2_1:1_153,Kka2,kka2_1:1,P00552,0.208961,NO,153,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.092,-3.83,2.738,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.520039,0.00501119,0.208961 kka2_1:8_G213T,kka2_1:8_213,Kka2,kka2_1:8,P00552,0.208998,NO,213,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.596,-3.675,3.079,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.100394,0.00187654,0.208998 kka2_1:8_G213T,kka2_1:8_213,Kka2,kka2_1:8,P00552,0.208998,NO,213,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.596,-3.675,3.079,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.100394,0.00187654,0.208998 beta-lactamase_625_S128I,beta-lactamase_625_128,TEM-1,beta-lactamase_625,P62593,0.209009,NO,128,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-0.84,-3.785,2.945,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.213352,0.00071483,0.209009 beta-lactamase_625_M115W,beta-lactamase_625_115,TEM-1,beta-lactamase_625,P62593,0.209038,NO,115,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.389,-5.031,3.642,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.213352,0.0034337,0.209038 kka2_1:4_L241F,kka2_1:4_241,Kka2,kka2_1:4,P00552,0.20908,NO,241,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.158,-1.703,0.545,,0.08,H,A,0.55,-0.82,1.598,,63.26,HHH,-1.58533,0.168804,0.0117299,0.20908 kka2_1:2_Y218E,kka2_1:2_218,Kka2,kka2_1:2,P00552,0.209106,NO,218,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-1.438,-3.729,2.291,,0.122,H,A,0.21,-0.69,1.022,,56.06,BHP,-1.17533,0.295029,0.0126098,0.209106 kka2_1:2_L170S,kka2_1:2_170,Kka2,kka2_1:2,P00552,0.209131,NO,170,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.28,-3.627,2.347,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.295029,0.00730791,0.209131 beta-lactamase_2500_A246I,beta-lactamase_2500_246,TEM-1,beta-lactamase_2500,P62593,0.209162,NO,246,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.121,-2.179,0.058,,0.01,E,B,0.46,-1.01,0.753,,73.78,HHH,-1.55633,0.361275,0.00569458,0.209162 kka2_1:1_L193E,kka2_1:1_193,Kka2,kka2_1:1,P00552,0.209172,NO,193,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.983,-3.783,2.8,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.520039,0.00480179,0.209172 beta-lactamase_39_T158K,beta-lactamase_39_158,TEM-1,beta-lactamase_39,P62593,0.20923,NO,158,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.116,-3.466,2.35,,0.036,,B,0.22,-0.85,2.755,,69.58,HPB,-1.269,0.0495842,0.00341825,0.20923 beta-lactamase_2500_I261G,beta-lactamase_2500_261,TEM-1,beta-lactamase_2500,P62593,0.209236,NO,261,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.361275,0.0123091,0.209236 kka2_1:2_E182R,kka2_1:2_182,Kka2,kka2_1:2,P00552,0.209239,NO,182,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.516,-3.801,2.285,,0.326,,B,1.52,0.75,14.547,14.547,65.53,OAA,-1.806,0.295029,0.00641548,0.209239 kka2_1:1_T28C,kka2_1:1_28,Kka2,kka2_1:1,P00552,0.209258,NO,28,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.883,-5.036,3.153,,0.353,S,B,0.22,2.02,1.12,,63.64,PPH,-1.74467,0.520039,0.00743084,0.209258 kka2_1:1_L19Q,kka2_1:1_19,Kka2,kka2_1:1,P00552,0.209348,NO,19,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.254,-4.298,3.044,,0.08,T,A,0.55,-0.26,17.165,17.165,65.53,BHH,-2.221,0.520039,0.00620703,0.209348 beta-lactamase_2500_D129R,beta-lactamase_2500_129,TEM-1,beta-lactamase_2500,P62593,0.209353,NO,129,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.816,-3.896,3.08,,,,B,0.75,-0.69,1.29,,34.97,PAP,-0.818,0.361275,0.00109178,0.209353 kka2_1:4_A119D,kka2_1:4_119,Kka2,kka2_1:4,P00552,0.209353,NO,119,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.073,-3.713,2.64,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.168804,0.00441074,0.209353 beta-lactamase_S128T,beta-lactamase_128,TEM-1,beta-lactamase,P62593,0.209459,NO,128,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-0.84,-2.971,2.131,5.37153,0.08,,L,0.73,-0.32,,,,HPA,-1.30233,0.221079,0.00071483,0.209459 kka2_1:1_M197H,kka2_1:1_197,Kka2,kka2_1:1,P00552,0.209533,NO,197,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.707,-4.99,3.283,,0.121,E,B,1.59,-1.19,2.097,,65.53,HHH,-1.847,0.520039,0.00921295,0.209533 kka2_1:4_F203S,kka2_1:4_203,Kka2,kka2_1:4,P00552,0.209535,NO,203,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-0.911,-3.673,2.762,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.168804,0.00318738,0.209535 kka2_1:1_V214T,kka2_1:1_214,Kka2,kka2_1:1,P00552,0.209537,NO,214,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.261,-3.47,2.209,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.520039,0.00692782,0.209537 beta-lactamase_625_L74K,beta-lactamase_625_74,TEM-1,beta-lactamase_625,P62593,0.209631,NO,74,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.296,-3.688,2.392,,,H,A,0.55,-0.91,0.895,,50,HHO,-1.34933,0.213352,0.00493255,0.209631 beta-lactamase_39_D129T,beta-lactamase_39_129,TEM-1,beta-lactamase_39,P62593,0.209639,NO,129,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.816,-3.447,2.631,,,,B,0.75,-0.69,0.56,,34.97,PAP,-0.818,0.0495842,0.00109178,0.209639 beta-lactamase_2500_V31Y,beta-lactamase_2500_31,TEM-1,beta-lactamase_2500,P62593,0.209658,NO,31,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.822,-4.027,2.205,,,H,A,0.44,-0.46,0.955,,73.78,BHB,-2.03767,0.361275,0.00478065,0.209658 Ubiquitin_I44K,Ubiquitin_44,Uba1,Ubiquitin,P0CG48,0.209677,NO,44,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.566,-3.733,2.167,4.71256,,E,B,0.27,-1.17,5.26,,39.71,HHH,-1.38567,0.205827,0.000613305,0.209677 Ubiquitin_K33P,Ubiquitin_33,Uba1,Ubiquitin,P0CG48,0.209677,NO,33,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.283,-3.865,2.582,5.08526,0.64,H,A,1.82,1.2,1.509,,51.09,ABA,-1.34267,0.205827,0.000712743,0.209677 Ubiquitin_K48C,Ubiquitin_48,Uba1,Ubiquitin,P0CG48,0.209677,NO,48,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.436,-5.102,3.666,5.03072,0.132,E,B,2.92,-0.28,1.539,,53.87,OBP,-1.6,0.205827,0.000394633,0.209677 Ubiquitin_L71P,Ubiquitin_71,Uba1,Ubiquitin,P0CG48,0.209677,NO,71,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.647,-3.019,1.372,5.02588,0.591,E,B,2.89,-0.69,4.365,,34.31,HHB,-1.85167,0.205827,0.000949314,0.209677 Ubiquitin_L71Y,Ubiquitin_71,Uba1,Ubiquitin,P0CG48,0.209677,NO,71,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.647,-3.906,2.259,5.02588,0.591,E,B,2.89,-0.69,4.365,,34.31,HHB,-1.85167,0.205827,0.000949314,0.209677 Ubiquitin_R72P,Ubiquitin_72,Uba1,Ubiquitin,P0CG48,0.209677,NO,72,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.034,-2.791,0.757,5.19484,0.077,,B,1.41,-0.1,9.638,9.638,42.77,HBH,-1.82733,0.205827,0.000768249,0.209677 Ubiquitin_V70E,Ubiquitin_70,Uba1,Ubiquitin,P0CG48,0.209677,NO,70,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.874,-2.905,1.031,5.29728,0.05,E,B,0.96,-0.97,2.363,,34.31,HHH,-1.65533,0.205827,0.00106871,0.209677 Ubiquitin_V70N,Ubiquitin_70,Uba1,Ubiquitin,P0CG48,0.209677,NO,70,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.874,-3.93,2.056,5.29728,0.05,E,B,0.96,-0.97,2.363,,34.31,HHH,-1.65533,0.205827,0.00106871,0.209677 beta-lactamase_156_K232D,beta-lactamase_156_232,TEM-1,beta-lactamase_156,P62593,0.209705,NO,232,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.012,-3.566,2.554,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.111618,0.00313441,0.209705 kka2_1:4_F263T,kka2_1:4_263,Kka2,kka2_1:4,P00552,0.209807,NO,263,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-0.911,-3.673,2.762,,0.006,G,A,0.58,-0.12,2.284,,45.83,AHH,-0.92,0.168804,0.0172454,0.209807 beta-lactamase_2500_G243D,beta-lactamase_2500_243,TEM-1,beta-lactamase_2500,P62593,0.209825,NO,243,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.361275,0.00464034,0.209825 kka2_1:2_R217T,kka2_1:2_217,Kka2,kka2_1:2,P00552,0.209841,NO,217,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.158,-3.559,2.401,,0.252,T,A,1.2,-0.59,0.381,,52.27,ABH,-1.127,0.295029,0.0047191,0.209841 kka2_1:4_F240N,kka2_1:4_240,Kka2,kka2_1:4,P00552,0.209842,NO,240,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-0.911,-4.185,3.274,,,H,A,0.58,-1.21,5.798,,50.38,BHH,-1.67267,0.168804,0.00552543,0.209842 beta-lactamase_625_T178W,beta-lactamase_625_178,TEM-1,beta-lactamase_625,P62593,0.209843,NO,178,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-0.791,-5.097,4.306,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.213352,0.000684366,0.209843 kka2_1:1_D250E,kka2_1:1_250,Kka2,kka2_1:1,P00552,0.209859,NO,250,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.015,-2.129,1.114,,0.274,.,b,0.75,-0.46,4.177,,51.89,OAP,-1.83933,0.520039,0.0177103,0.209859 kka2_1:8_L232G,kka2_1:8_232,Kka2,kka2_1:8,P00552,0.209911,NO,232,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.514,-2.969,1.455,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.100394,0.00800103,0.209911 kka2_1:8_L232G,kka2_1:8_232,Kka2,kka2_1:8,P00552,0.209911,NO,232,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.514,-2.969,1.455,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.100394,0.00800103,0.209911 kka2_1:2_D261P,kka2_1:2_261,Kka2,kka2_1:2,P00552,0.209918,NO,261,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.708,-3.683,2.975,,0.146,G,A,0.75,-0.33,,,,HAA,-0.759333,0.295029,0.0224846,0.209918 beta-lactamase_625_C75H,beta-lactamase_625_75,TEM-1,beta-lactamase_625,P62593,0.210011,NO,75,C,H,CH,Special,PositiveCharge,5.07,7.59,2.52,174,121,155,34,108.5,153.2,44.7,-1.245,-4.871,3.626,,,H,A,0.46,-0.87,2.141,,50,HOO,-1.24333,0.213352,0.0034616,0.210011 kka2_1:1_A255F,kka2_1:1_255,Kka2,kka2_1:1,P00552,0.210037,NO,255,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.715,-3.34,1.625,,0.466,H,A,0.46,-0.52,0.946,,65.53,HHH,-1.71267,0.520039,0.0126809,0.210037 kka2_1:4_P45W,kka2_1:4_45,Kka2,kka2_1:4,P00552,0.210056,NO,45,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.774,-5.588,3.814,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.168804,0.00590481,0.210056 beta-lactamase_156_S68A,beta-lactamase_156_68,TEM-1,beta-lactamase_156,P62593,0.210073,NO,68,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-0.913,-2.711,1.798,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.111618,0.000800065,0.210073 kka2_1:4_C77I,kka2_1:4_77,Kka2,kka2_1:4,P00552,0.210076,NO,77,C,I,CI,Special,Hydrophobic,5.07,6.02,0.95,198,121,131,10,108.5,166.7,58.2,-1.477,-3.673,2.196,,0.229,B,b,0.46,-0.57,2.499,,63.26,OOH,-1.55667,0.168804,0.00441216,0.210076 kka2_1:2_V186Y,kka2_1:2_186,Kka2,kka2_1:2,P00552,0.21014,NO,186,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.011,-3.942,2.931,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.295029,0.00409703,0.21014 kka2_1:4_Q219W,kka2_1:4_219,Kka2,kka2_1:4,P00552,0.210153,NO,219,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-0.93,-5.169,4.239,,0.088,H,A,0.64,-0.85,1.537,,50,HPA,-1.05167,0.168804,0.00237913,0.210153 beta-lactamase_39_I280P,beta-lactamase_39_280,TEM-1,beta-lactamase_39,P62593,0.210208,NO,280,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.0495842,0.0530888,0.210208 kka2_1:1_A137H,kka2_1:1_137,Kka2,kka2_1:1,P00552,0.210224,NO,137,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.156,-4.943,2.787,,0.029,H,A,0.46,0.34,1.323,,63.26,PHB,-2.559,0.520039,0.00515054,0.210224 beta-lactamase_156_C75H,beta-lactamase_156_75,TEM-1,beta-lactamase_156,P62593,0.210302,NO,75,C,H,CH,Special,PositiveCharge,5.07,7.59,2.52,174,121,155,34,108.5,153.2,44.7,-1.245,-4.871,3.626,,,H,A,0.46,-0.87,0.876,,50,HOO,-1.24333,0.111618,0.0034616,0.210302 kka2_1:1_F206I,kka2_1:1_206,Kka2,kka2_1:1,P00552,0.210308,NO,206,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.349,-3.398,2.049,,0.006,E,B,0.58,-1.21,0.978,,63.64,OHH,-1.04,0.520039,0.00936868,0.210308 kka2_1:1_C77W,kka2_1:1_77,Kka2,kka2_1:1,P00552,0.21033,NO,77,C,W,CW,Special,Hydrophobic,5.07,5.89,0.82,215,121,204,83,108.5,227.8,119.3,-1.477,-5.341,3.864,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.520039,0.00441216,0.21033 beta-lactamase_625_N130F,beta-lactamase_625_130,TEM-1,beta-lactamase_625,P62593,0.210345,NO,130,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-0.798,-4.292,3.494,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.213352,0.000683376,0.210345 kka2_1:2_V113N,kka2_1:2_113,Kka2,kka2_1:2,P00552,0.21035,NO,113,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.233,-4.251,3.018,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.295029,0.00650191,0.21035 kka2_1:1_Y218E,kka2_1:1_218,Kka2,kka2_1:1,P00552,0.210402,NO,218,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-1.438,-3.729,2.291,,0.122,H,A,1.25,-0.69,3.059,,56.06,BHP,-1.17533,0.520039,0.0126098,0.210402 kka2_1:2_I141E,kka2_1:2_141,Kka2,kka2_1:2,P00552,0.210431,NO,141,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.495,-3.998,2.503,,0.068,H,A,0.48,-0.01,0.819,,92.05,BHA,-1.689,0.295029,0.00744745,0.210431 E1_Ubiquitin_G75F,E1_Ubiquitin_75,Uba1,E1_Ubiquitin,P0CG63,0.210433,NO,75,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.999,-4.162,3.163,,0.552,T,A,0.75,0.9,4.369,,83.73,BOO,-1.1,0.18783,0.00153276,0.210433 kka2_1:8_W236T,kka2_1:8_236,Kka2,kka2_1:8,P00552,0.210457,NO,236,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-1.363,-3.713,2.35,,0.303,H,A,1.51,-0.76,1.87,,48.48,AHH,-1.81267,0.100394,0.0088796,0.210457 kka2_1:8_W236T,kka2_1:8_236,Kka2,kka2_1:8,P00552,0.210457,NO,236,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-1.363,-3.713,2.35,,0.303,H,A,1.51,-0.76,1.87,,48.48,AHH,-1.81267,0.100394,0.0088796,0.210457 kka2_1:1_A150L,kka2_1:1_150,Kka2,kka2_1:1,P00552,0.210463,NO,150,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.949,-3.346,2.397,,0.544,T,A,0.46,1.34,2.333,,63.26,AHO,-1.272,0.520039,0.0045009,0.210463 beta-lactamase_625_L284P,beta-lactamase_625_284,TEM-1,beta-lactamase_625,P62593,0.210464,NO,284,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.213352,0.0686156,0.210464 beta-lactamase_625_L167Q,beta-lactamase_625_167,TEM-1,beta-lactamase_625,P62593,0.210487,NO,167,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.138,-4.038,2.9,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.213352,0.00303566,0.210487 kka2_1:1_D118F,kka2_1:1_118,Kka2,kka2_1:1,P00552,0.210609,NO,118,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.07,-4.414,2.344,,0.61,H,A,0.75,-0.05,13.434,13.434,64.39,HAH,-1.32367,0.520039,0.0067852,0.210609 kka2_1:2_L212D,kka2_1:2_212,Kka2,kka2_1:2,P00552,0.210617,NO,212,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.904,-4.134,3.23,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.295029,0.0031426,0.210617 beta-lactamase_625_Y44T,beta-lactamase_625_44,TEM-1,beta-lactamase_625,P62593,0.210667,NO,44,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-2.547,-2.836,0.289,,,E,B,0.21,-0.45,2.371,,73.78,OHH,-1.86267,0.213352,0.00426364,0.210667 kka2_1:2_L193E,kka2_1:2_193,Kka2,kka2_1:2,P00552,0.210683,NO,193,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.983,-3.783,2.8,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.295029,0.00480179,0.210683 kka2_1:2_S40P,kka2_1:2_40,Kka2,kka2_1:2,P00552,0.210734,NO,40,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.645,-3.224,0.579,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.295029,0.00693477,0.210734 beta-lactamase_156_P181D,beta-lactamase_156_181,TEM-1,beta-lactamase_156,P62593,0.210771,NO,181,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.813,-3.518,2.705,,,H,A,0.52,-1.14,1.078,,61.54,HOH,-1.795,0.111618,0.000703122,0.210771 beta-lactamase_2500_E56P,beta-lactamase_2500_56,TEM-1,beta-lactamase_2500,P62593,0.210811,NO,56,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.043,-3.731,1.688,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.361275,0.00238534,0.210811 kka2_1:8_D216W,kka2_1:8_216,Kka2,kka2_1:8,P00552,0.210821,NO,216,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.785,-5.543,4.758,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.100394,0.00229969,0.210821 kka2_1:8_D216W,kka2_1:8_216,Kka2,kka2_1:8,P00552,0.210821,NO,216,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.785,-5.543,4.758,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.100394,0.00229969,0.210821 beta-lactamase_156_R257W,beta-lactamase_156_257,TEM-1,beta-lactamase_156,P62593,0.210823,NO,257,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.111618,0.00756629,0.210823 beta-lactamase_39_I280E,beta-lactamase_39_280,TEM-1,beta-lactamase_39,P62593,0.210857,NO,280,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.0495842,0.0530888,0.210857 kka2_1:2_T187E,kka2_1:2_187,Kka2,kka2_1:2,P00552,0.210869,NO,187,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.273,-3.655,2.382,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.295029,0.00693073,0.210869 beta-lactamase_2500_I261P,beta-lactamase_2500_261,TEM-1,beta-lactamase_2500,P62593,0.210877,NO,261,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.361275,0.0123091,0.210877 kka2_1:1_A79L,kka2_1:1_79,Kka2,kka2_1:1,P00552,0.210887,NO,79,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.368,-3.577,1.209,,0.563,.,B,0.46,-0.43,7.792,7.792,71.59,HHH,-1.752,0.520039,0.00664821,0.210887 kka2_1:1_D82T,kka2_1:1_82,Kka2,kka2_1:1,P00552,0.210917,NO,82,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.946,-3.007,1.061,,0.341,E,b,0.75,0.52,11.345,11.345,63.64,HAH,-1.98,0.520039,0.00637516,0.210917 beta-lactamase_625_L74W,beta-lactamase_625_74,TEM-1,beta-lactamase_625,P62593,0.21098,NO,74,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.296,-5.261,3.965,,,H,A,0.55,-0.91,0.895,,50,HHO,-1.34933,0.213352,0.00493255,0.21098 beta-lactamase_156_L79W,beta-lactamase_156_79,TEM-1,beta-lactamase_156,P62593,0.211026,NO,79,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.842,-5.095,4.253,,0.007,H,A,0.55,-0.16,1.831,,50.35,HHP,-1.44333,0.111618,0.000947397,0.211026 beta-lactamase_625_Y95K,beta-lactamase_625_95,TEM-1,beta-lactamase_625,P62593,0.211178,NO,95,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-1.715,-3.936,2.221,,0.122,,b,0.21,-0.37,3.355,,77.62,BHP,-2.16167,0.213352,0.00479449,0.211178 kka2_1:8_R140N,kka2_1:8_140,Kka2,kka2_1:8,P00552,0.211185,NO,140,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.351,-3.614,2.263,,0.12,H,A,0.16,0.2,2.874,,53.03,BBH,-1.885,0.100394,0.00430167,0.211185 kka2_1:8_R140N,kka2_1:8_140,Kka2,kka2_1:8,P00552,0.211185,NO,140,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.351,-3.614,2.263,,0.12,H,A,0.16,0.2,2.874,,53.03,BBH,-1.885,0.100394,0.00430167,0.211185 kka2_1:8_V36W,kka2_1:8_36,Kka2,kka2_1:8,P00552,0.211185,NO,36,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-0.898,-5.395,4.497,,0.292,E,B,1.48,0.21,0.938,,52.27,HHH,-1.484,0.100394,0.00245633,0.211185 kka2_1:8_V36W,kka2_1:8_36,Kka2,kka2_1:8,P00552,0.211185,NO,36,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-0.898,-5.395,4.497,,0.292,E,B,1.48,0.21,0.938,,52.27,HHH,-1.484,0.100394,0.00245633,0.211185 kka2_1:1_L241N,kka2_1:1_241,Kka2,kka2_1:1,P00552,0.21123,NO,241,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.158,-4.222,3.064,,0.08,H,A,0.55,-0.82,1.685,,63.26,HHH,-1.58533,0.520039,0.0117299,0.21123 beta-lactamase_625_W208P,beta-lactamase_625_208,TEM-1,beta-lactamase_625,P62593,0.211254,NO,208,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-0.818,-4.33,3.512,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.213352,0.00126609,0.211254 kka2_1:2_N200M,kka2_1:2_200,Kka2,kka2_1:2,P00552,0.211271,NO,200,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-2.446,-4.957,2.511,,0.756,T,L,0.61,-0.08,2.836,,64.39,APO,-2.08,0.295029,0.00838549,0.211271 kka2_1:1_A71W,kka2_1:1_71,Kka2,kka2_1:1,P00552,0.211277,NO,71,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.824,-5.529,3.705,,0.553,H,A,0.46,0.08,9.788,,64.39,HHP,-1.74033,0.520039,0.00727707,0.211277 kka2_1:2_V36H,kka2_1:2_36,Kka2,kka2_1:2,P00552,0.211289,NO,36,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-0.898,-4.978,4.08,,0.292,E,B,1.48,0.21,1.064,,52.27,HHH,-1.484,0.295029,0.00245633,0.211289 beta-lactamase_S233Q,beta-lactamase_233,TEM-1,beta-lactamase,P62593,0.211325,NO,233,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.886,-3.939,2.053,4.98121,0.016,E,B,0.48,-1.01,5.361,,77.62,BPO,-1.17267,0.221079,0.00311415,0.211325 beta-lactamase_625_D129L,beta-lactamase_625_129,TEM-1,beta-lactamase_625,P62593,0.211395,NO,129,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.816,-3.806,2.99,,,,B,0.75,-0.69,0.171,,34.97,PAP,-0.818,0.213352,0.00109178,0.211395 beta-lactamase_156_N134P,beta-lactamase_156_134,TEM-1,beta-lactamase_156,P62593,0.211414,NO,134,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-0.879,-3.877,2.998,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.111618,0.000644786,0.211414 beta-lactamase_156_T187P,beta-lactamase_156_187,TEM-1,beta-lactamase_156,P62593,0.211537,NO,187,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.401,-3.906,2.505,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.111618,0.00491782,0.211537 kka2_1:2_R258Y,kka2_1:2_258,Kka2,kka2_1:2,P00552,0.211571,NO,258,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.626,-4.283,2.657,,0.316,H,A,1.2,-0.85,7.485,7.485,53.03,HBH,-1.25933,0.295029,0.00983174,0.211571 kka2_1:1_P45W,kka2_1:1_45,Kka2,kka2_1:1,P00552,0.211576,NO,45,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.774,-5.588,3.814,,0.669,.,B,0.52,-0.76,4.882,,71.59,BOH,-2.152,0.520039,0.00590481,0.211576 beta-lactamase_625_A247P,beta-lactamase_625_247,TEM-1,beta-lactamase_625,P62593,0.211614,NO,247,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.213352,0.00611275,0.211614 beta-lactamase_2500_F70Y,beta-lactamase_2500_70,TEM-1,beta-lactamase_2500,P62593,0.211619,NO,70,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.169,-2.563,1.394,,,H,A,0.58,-1.34,1.918,,63.99,PHB,-0.980667,0.361275,0.00193499,0.211619 kka2_1:4_V185K,kka2_1:4_185,Kka2,kka2_1:4,P00552,0.211631,NO,185,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.045,-3.785,2.74,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.168804,0.00367031,0.211631 kka2_1:1_L260K,kka2_1:1_260,Kka2,kka2_1:1,P00552,0.211667,NO,260,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.741,-3.71,2.969,,0.022,H,A,0.55,-0.52,,,,HHA,-0.845667,0.520039,0.0233782,0.211667 beta-lactamase_2500_M184S,beta-lactamase_2500_184,TEM-1,beta-lactamase_2500,P62593,0.211704,NO,184,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.593,-3.463,1.87,,,H,A,0.55,-0.87,2.893,,62.94,HHH,-1.41,0.361275,0.00356019,0.211704 kka2_1:2_H162P,kka2_1:2_162,Kka2,kka2_1:2,P00552,0.211715,NO,162,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-2.319,-4.047,1.728,,0.071,G,A,0.17,1.01,3.187,,64.39,ABP,-2.02067,0.295029,0.00616145,0.211715 kka2_1:4_N195L,kka2_1:4_195,Kka2,kka2_1:4,P00552,0.211746,NO,195,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-0.836,-3.655,2.819,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.168804,0.00276134,0.211746 beta-lactamase_39_A185F,beta-lactamase_39_185,TEM-1,beta-lactamase_39,P62593,0.211792,NO,185,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.406,-4.091,2.685,,,H,A,0.46,-1.02,2.68,,65.03,HHP,-1.84033,0.0495842,0.00467449,0.211792 beta-lactamase_156_L248G,beta-lactamase_156_248,TEM-1,beta-lactamase_156,P62593,0.211796,NO,248,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.794,-3.512,1.718,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.111618,0.00428493,0.211796 kka2_1:1_F171W,kka2_1:1_171,Kka2,kka2_1:1,P00552,0.21187,NO,171,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.326,-4.742,3.416,,0.154,H,A,1.62,-0.1,13.679,13.679,63.64,HHH,-1.45433,0.520039,0.00821426,0.21187 beta-lactamase_0_D83M,beta-lactamase_0_83,TEM-1,beta-lactamase_0,P62593,0.211878,NO,83,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.066,-4.912,3.846,,0.354,H,A,0.75,0.22,0.617,,48.95,HAH,-1.34733,0.0500837,0.00205968,0.211878 beta-lactamase_2500_L135W,beta-lactamase_2500_135,TEM-1,beta-lactamase_2500,P62593,0.211956,NO,135,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.002,-5.166,4.164,,0.117,H,A,0.55,-0.58,0.795,,43.71,PHH,-1.03767,0.361275,0.00244423,0.211956 kka2_1:1_A71Y,kka2_1:1_71,Kka2,kka2_1:1,P00552,0.211992,NO,71,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.824,-4.36,2.536,,0.553,H,A,0.46,0.08,9.788,,64.39,HHP,-1.74033,0.520039,0.00727707,0.211992 beta-lactamase_2500_L167S,beta-lactamase_2500_167,TEM-1,beta-lactamase_2500,P62593,0.212001,NO,167,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.138,-2.747,1.609,,0.015,G,A,0.55,-0.63,7.813,,64.69,AHP,-1.30767,0.361275,0.00303566,0.212001 beta-lactamase_2500_S128C,beta-lactamase_2500_128,TEM-1,beta-lactamase_2500,P62593,0.21204,NO,128,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-0.84,-4.637,3.797,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.361275,0.00071483,0.21204 beta-lactamase_156_I280P,beta-lactamase_156_280,TEM-1,beta-lactamase_156,P62593,0.212064,NO,280,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.111618,0.0530888,0.212064 beta-lactamase_156_G281P,beta-lactamase_156_281,TEM-1,beta-lactamase_156,P62593,0.212074,NO,281,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.111618,0.0406482,0.212074 kka2_1:8_T187M,kka2_1:8_187,Kka2,kka2_1:8,P00552,0.212091,NO,187,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.273,-4.606,3.333,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.100394,0.00693073,0.212091 kka2_1:8_T187M,kka2_1:8_187,Kka2,kka2_1:8,P00552,0.212091,NO,187,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.273,-4.606,3.333,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.100394,0.00693073,0.212091 beta-lactamase_156_I280Y,beta-lactamase_156_280,TEM-1,beta-lactamase_156,P62593,0.212105,NO,280,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.111618,0.0530888,0.212105 beta-lactamase_2500_W208V,beta-lactamase_2500_208,TEM-1,beta-lactamase_2500,P62593,0.21219,NO,208,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-0.818,-3.754,2.936,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.361275,0.00126609,0.21219 E1_Ubiquitin_G76Q,E1_Ubiquitin_76,Uba1,E1_Ubiquitin,P0CG63,0.212202,NO,76,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.999,-3.995,2.996,,0.23,,B,0.75,0.08,1.702,,83.73,OOO,-0.999,0.18783,0.00125575,0.212202 E1_Ubiquitin_R72D,E1_Ubiquitin_72,Uba1,E1_Ubiquitin,P0CG63,0.212202,NO,72,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.184,-3.511,2.327,,0.077,,B,0.16,-0.1,,,,HBH,-1.08733,0.18783,0.00129853,0.212202 kka2_1:1_E111I,kka2_1:1_111,Kka2,kka2_1:1,P00552,0.212214,NO,111,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.28,-4.031,1.751,,0.155,H,A,1.52,-1.14,15.716,15.716,65.53,HAB,-2.27833,0.520039,0.00746789,0.212214 kka2_1:1_K138M,kka2_1:1_138,Kka2,kka2_1:1,P00552,0.212276,NO,138,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-2.5,-4.844,2.344,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.520039,0.00628542,0.212276 kka2_1:1_F48C,kka2_1:1_48,Kka2,kka2_1:1,P00552,0.212295,NO,48,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.453,-4.951,3.498,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.520039,0.00475422,0.212295 beta-lactamase_625_G142W,beta-lactamase_625_142,TEM-1,beta-lactamase_625,P62593,0.212367,NO,142,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.707,-5.146,4.439,,0.034,,p,0.29,-0.64,1.35,,64.69,OOO,-0.834,0.213352,0.00060149,0.212367 kka2_1:1_P132W,kka2_1:1_132,Kka2,kka2_1:1,P00552,0.212376,NO,132,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.775,-5.574,4.799,,0.692,.,A,0.52,0.56,0.224,,44.7,OOH,-0.825667,0.520039,0.0018489,0.212376 kka2_1:2_L259E,kka2_1:2_259,Kka2,kka2_1:2,P00552,0.212381,NO,259,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.088,-3.851,2.763,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.295029,0.0206964,0.212381 beta-lactamase_625_I245D,beta-lactamase_625_245,TEM-1,beta-lactamase_625,P62593,0.212418,NO,245,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.213352,0.00391032,0.212418 kka2_1:8_F206G,kka2_1:8_206,Kka2,kka2_1:8,P00552,0.212453,NO,206,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.349,-3.746,2.397,,0.006,E,B,1.62,-1.21,1.052,,63.64,OHH,-1.04,0.100394,0.00936868,0.212453 kka2_1:8_F206G,kka2_1:8_206,Kka2,kka2_1:8,P00552,0.212453,NO,206,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.349,-3.746,2.397,,0.006,E,B,1.62,-1.21,1.052,,63.64,OHH,-1.04,0.100394,0.00936868,0.212453 beta-lactamase_625_G249V,beta-lactamase_625_249,TEM-1,beta-lactamase_625,P62593,0.212461,NO,249,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.213352,0.00220169,0.212461 beta-lactamase_156_K232A,beta-lactamase_156_232,TEM-1,beta-lactamase_156,P62593,0.212466,NO,232,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.012,-3.12,2.108,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.111618,0.00313441,0.212466 beta-lactamase_625_L205Q,beta-lactamase_625_205,TEM-1,beta-lactamase_625,P62593,0.212472,NO,205,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.922,-4.179,3.257,,,H,A,0.55,-0.46,3.782,,42.31,PHH,-1.57767,0.213352,0.00255802,0.212472 kka2_1:2_N200F,kka2_1:2_200,Kka2,kka2_1:2,P00552,0.212473,NO,200,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-2.446,-4.524,2.078,,0.756,T,L,0.61,-0.08,2.836,,64.39,APO,-2.08,0.295029,0.00838549,0.212473 beta-lactamase_156_V31D,beta-lactamase_156_31,TEM-1,beta-lactamase_156,P62593,0.212474,NO,31,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.822,-4.049,2.227,,,H,A,0.44,-0.46,4.126,,73.78,BHB,-2.03767,0.111618,0.00478065,0.212474 Pab1_I196G,Pab1_196,Pab1,Pab1,P04147,0.212475,NO,196,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.795,-3.544,1.749,,,,,,,2.013,,80.59,AHH,-1.44667,0.175299,0.0016933,0.212475 beta-lactamase_156_G234V,beta-lactamase_156_234,TEM-1,beta-lactamase_156,P62593,0.212501,NO,234,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.62,-3.754,3.134,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.111618,0.000889577,0.212501 kka2_1:1_D127V,kka2_1:1_127,Kka2,kka2_1:1,P00552,0.212505,NO,127,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.364,-3.744,2.38,,0.573,.,B,0.75,0.45,3.414,,50.38,HAO,-1.51067,0.520039,0.00660501,0.212505 beta-lactamase_2500_I261N,beta-lactamase_2500_261,TEM-1,beta-lactamase_2500,P62593,0.21252,NO,261,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.361275,0.0123091,0.21252 beta-lactamase_T69Q,beta-lactamase_69,TEM-1,beta-lactamase,P62593,0.212566,NO,69,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-0.973,-3.935,2.962,5.16042,,G,A,0.69,-1.24,0.505,,93.01,PPH,-1.01833,0.221079,0.00127498,0.212566 kka2_1:2_L107N,kka2_1:2_107,Kka2,kka2_1:2,P00552,0.212583,NO,107,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.238,-4.107,2.869,,0.197,,B,1.59,-1.1,2.68,,71.59,BHH,-2.143,0.295029,0.00561937,0.212583 beta-lactamase_156_K71E,beta-lactamase_156_71,TEM-1,beta-lactamase_156,P62593,0.212609,NO,71,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-0.8,-2.99,2.19,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.111618,0.00103192,0.212609 kka2_1:2_I141K,kka2_1:2_141,Kka2,kka2_1:2,P00552,0.212612,NO,141,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.495,-3.912,2.417,,0.068,H,A,0.48,-0.01,0.819,,92.05,BHA,-1.689,0.295029,0.00744745,0.212612 beta-lactamase_156_G243E,beta-lactamase_156_243,TEM-1,beta-lactamase_156,P62593,0.2127,NO,243,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.532,,,,,E,B,0.77,-1.24,2.866,,50,BOH,-1.46867,0.111618,0.00464034,0.2127 beta-lactamase_2500_L79K,beta-lactamase_2500_79,TEM-1,beta-lactamase_2500,P62593,0.212714,NO,79,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.842,-3.679,2.837,,0.007,H,A,0.55,-0.16,0.823,,50.35,HHP,-1.44333,0.361275,0.000947397,0.212714 kka2_1:1_R211A,kka2_1:1_211,Kka2,kka2_1:1,P00552,0.212752,NO,211,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-0.899,-3.167,2.268,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.520039,0.00204888,0.212752 kka2_1:2_V97Q,kka2_1:2_97,Kka2,kka2_1:2,P00552,0.21281,NO,97,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.453,-4.252,2.799,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.295029,0.00737869,0.21281 kka2_1:1_L260A,kka2_1:1_260,Kka2,kka2_1:1,P00552,0.212826,NO,260,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.741,-3.106,2.365,,0.022,H,A,0.55,-0.52,,,,HHA,-0.845667,0.520039,0.0233782,0.212826 beta-lactamase_625_G76N,beta-lactamase_625_76,TEM-1,beta-lactamase_625,P62593,0.212888,NO,76,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.189,-3.655,2.466,,,H,A,0.29,-0.67,3.059,,67.83,OOH,-1.22267,0.213352,0.00476637,0.212888 kka2_1:4_I196Y,kka2_1:4_196,Kka2,kka2_1:4,P00552,0.212946,NO,196,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-2.115,-2.902,0.787,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.168804,0.0107273,0.212946 kka2_1:1_A168D,kka2_1:1_168,Kka2,kka2_1:1,P00552,0.213039,NO,168,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.989,-2.545,0.556,,0.67,H,A,0.46,0.15,25.546,25.546,64.39,OHA,-2.12933,0.520039,0.00806773,0.213039 kka2_1:1_D82E,kka2_1:1_82,Kka2,kka2_1:1,P00552,0.213049,NO,82,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.946,-2.436,0.49,,0.341,E,b,0.75,0.52,11.345,11.345,63.64,HAH,-1.98,0.520039,0.00637516,0.213049 beta-lactamase_2500_I229T,beta-lactamase_2500_229,TEM-1,beta-lactamase_2500,P62593,0.213127,NO,229,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.267,-2.621,1.354,,0.083,E,B,0.48,-0.76,3.875,,50,HHH,-1.58767,0.361275,0.00477249,0.213127 kka2_1:4_A117P,kka2_1:4_117,Kka2,kka2_1:4,P00552,0.213174,NO,117,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.828,-3.747,2.919,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.168804,0.00282984,0.213174 kka2_1:8_V49P,kka2_1:8_49,Kka2,kka2_1:8,P00552,0.213356,NO,49,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.614,-4.128,2.514,,,E,B,1.48,-0.77,1.31,,64.39,HHB,-1.3,0.100394,0.00615685,0.213356 kka2_1:8_V49P,kka2_1:8_49,Kka2,kka2_1:8,P00552,0.213356,NO,49,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.614,-4.128,2.514,,,E,B,1.48,-0.77,1.31,,64.39,HHB,-1.3,0.100394,0.00615685,0.213356 beta-lactamase_2500_C75E,beta-lactamase_2500_75,TEM-1,beta-lactamase_2500,P62593,0.213386,NO,75,C,E,CE,Special,negativeCharge,5.07,3.22,-1.85,170,121,147,26,108.5,138.4,29.9,-1.245,-3.874,2.629,,,H,A,0.46,-0.87,0.844,,50,HOO,-1.24333,0.361275,0.0034616,0.213386 kka2_1:1_T130W,kka2_1:1_130,Kka2,kka2_1:1,P00552,0.213406,NO,130,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.392,-5.541,3.149,,0.561,G,A,0.22,0.77,0.5,,92.05,HPO,-1.62633,0.520039,0.00804204,0.213406 kka2_1:2_G213F,kka2_1:2_213,Kka2,kka2_1:2,P00552,0.213421,NO,213,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.596,-4.32,3.724,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.295029,0.00187654,0.213421 kka2_1:1_G164F,kka2_1:1_164,Kka2,kka2_1:1,P00552,0.213447,NO,164,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.869,-4.375,3.506,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.520039,0.00442091,0.213447 beta-lactamase_156_P181H,beta-lactamase_156_181,TEM-1,beta-lactamase_156,P62593,0.213542,NO,181,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.813,-4.706,3.893,,,H,A,0.52,-1.14,1.078,,61.54,HOH,-1.795,0.111618,0.000703122,0.213542 beta-lactamase_2500_T158K,beta-lactamase_2500_158,TEM-1,beta-lactamase_2500,P62593,0.213603,NO,158,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.116,-3.466,2.35,,0.036,,B,0.22,-0.85,1.344,,69.58,HPB,-1.269,0.361275,0.00341825,0.213603 beta-lactamase_2500_N130A,beta-lactamase_2500_130,TEM-1,beta-lactamase_2500,P62593,0.213657,NO,130,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-0.798,-3.303,2.505,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.361275,0.000683376,0.213657 beta-lactamase_625_I277R,beta-lactamase_625_277,TEM-1,beta-lactamase_625,P62593,0.213718,NO,277,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.213352,0.0169305,0.213718 kka2_1:2_R217E,kka2_1:2_217,Kka2,kka2_1:2,P00552,0.213772,NO,217,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.158,-3.44,2.282,,0.252,T,A,1.2,-0.59,0.381,,52.27,ABH,-1.127,0.295029,0.0047191,0.213772 beta-lactamase_2500_R59I,beta-lactamase_2500_59,TEM-1,beta-lactamase_2500,P62593,0.213795,NO,59,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.345,-4.065,2.72,,0.329,S,L,1.2,-0.09,3.719,,73.08,HBO,-2.24267,0.361275,0.00318082,0.213795 kka2_1:1_L67Y,kka2_1:1_67,Kka2,kka2_1:1,P00552,0.213829,NO,67,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.741,-3.966,3.225,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.520039,0.00102787,0.213829 kka2_1:2_L243W,kka2_1:2_243,Kka2,kka2_1:2,P00552,0.213844,NO,243,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-2.651,-5.55,2.899,,0.277,H,A,1.59,-0.67,13.165,13.165,92.05,HHH,-2.03767,0.295029,0.00884927,0.213844 kka2_1:1_A9W,kka2_1:1_9,Kka2,kka2_1:1,P00552,0.213849,NO,9,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.079,-5.293,3.214,,,,,,,0.383,,71.59,BHO,-2.253,0.520039,0.00273264,0.213849 kka2_1:1_E111M,kka2_1:1_111,Kka2,kka2_1:1,P00552,0.21386,NO,111,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.28,-4.788,2.508,,0.155,H,A,1.52,-1.14,15.716,15.716,65.53,HAB,-2.27833,0.520039,0.00746789,0.21386 beta-lactamase_625_L160R,beta-lactamase_625_160,TEM-1,beta-lactamase_625,P62593,0.213877,NO,160,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.977,-4.03,3.053,,0.022,,B,0.55,-0.6,0.237,,44.41,BHA,-0.936,0.213352,0.00193775,0.213877 kka2_1:2_L174I,kka2_1:2_174,Kka2,kka2_1:2,P00552,0.213894,NO,174,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.952,-3.013,2.061,,,H,A,1.59,-0.31,8.521,,51.89,BHB,-2.08533,0.295029,0.00438501,0.213894 beta-lactamase_625_E119F,beta-lactamase_625_119,TEM-1,beta-lactamase_625,P62593,0.213906,NO,119,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.412,-4.398,2.986,,0.358,H,A,1.04,0.51,1.034,,63.99,BAH,-1.623,0.213352,0.00386966,0.213906 beta-lactamase_625_I125K,beta-lactamase_625_125,TEM-1,beta-lactamase_625,P62593,0.213946,NO,125,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.441,-3.825,2.384,,,H,A,0.48,-0.7,2.034,,63.29,HHP,-1.248,0.213352,0.00383964,0.213946 kka2_1:1_F171N,kka2_1:1_171,Kka2,kka2_1:1,P00552,0.214061,NO,171,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.326,-4.165,2.839,,0.154,H,A,1.62,-0.1,13.679,13.679,63.64,HHH,-1.45433,0.520039,0.00821426,0.214061 kka2_1:4_I115R,kka2_1:4_115,Kka2,kka2_1:4,P00552,0.214087,NO,115,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.606,-4.203,2.597,,0.105,H,A,1.52,-1.18,9.996,9.996,65.53,PHH,-2.205,0.168804,0.00836567,0.214087 beta-lactamase_39_L73R,beta-lactamase_39_73,TEM-1,beta-lactamase_39,P62593,0.214227,NO,73,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.507,-4.144,2.637,,,H,A,0.55,-0.64,2.09,,67.83,HHH,-1.487,0.0495842,0.00488983,0.214227 beta-lactamase_625_A77P,beta-lactamase_625_77,TEM-1,beta-lactamase_625,P62593,0.21428,NO,77,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.234,-3.879,2.645,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.213352,0.00282362,0.21428 beta-lactamase_625_M66P,beta-lactamase_625_66,TEM-1,beta-lactamase_625,P62593,0.214298,NO,66,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.362,-4.047,2.685,,0.013,,A,0.55,-0.7,1.659,,73.08,OHH,-1.49567,0.213352,0.00412876,0.214298 kka2_1:2_F240N,kka2_1:2_240,Kka2,kka2_1:2,P00552,0.214336,NO,240,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-0.911,-4.185,3.274,,,H,A,0.58,-1.21,0.373,,50.38,BHH,-1.67267,0.295029,0.00552543,0.214336 beta-lactamase_625_F70E,beta-lactamase_625_70,TEM-1,beta-lactamase_625,P62593,0.214409,NO,70,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.169,-3.82,2.651,,,H,A,0.58,-1.34,1.14,,63.99,PHB,-0.980667,0.213352,0.00193499,0.214409 kka2_1:8_D159I,kka2_1:8_159,Kka2,kka2_1:8,P00552,0.214437,NO,159,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.82,-4.102,3.282,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.100394,0.0030485,0.214437 kka2_1:8_D159I,kka2_1:8_159,Kka2,kka2_1:8,P00552,0.214437,NO,159,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.82,-4.102,3.282,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.100394,0.0030485,0.214437 kka2_1:8_W91P,kka2_1:8_91,Kka2,kka2_1:8,P00552,0.214437,NO,91,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-1.178,-4.336,3.158,,0.077,E,B,1.51,0.27,2.51,,48.48,AHH,-1.51,0.100394,0.00358653,0.214437 kka2_1:8_W91P,kka2_1:8_91,Kka2,kka2_1:8,P00552,0.214437,NO,91,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-1.178,-4.336,3.158,,0.077,E,B,1.51,0.27,2.51,,48.48,AHH,-1.51,0.100394,0.00358653,0.214437 beta-lactamase_F64A,beta-lactamase_64,TEM-1,beta-lactamase,P62593,0.214517,NO,64,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-0.841,-3.303,2.462,5.70769,0.006,E,B,1.33,-0.95,,,,BHO,-0.892667,0.221079,0.000947691,0.214517 beta-lactamase_2500_D48T,beta-lactamase_2500_48,TEM-1,beta-lactamase_2500,P62593,0.214533,NO,48,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.101,-3.511,2.41,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.361275,0.0027273,0.214533 kka2_1:1_D190S,kka2_1:1_190,Kka2,kka2_1:1,P00552,0.214575,NO,190,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.708,-3.189,2.481,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.520039,0.00247989,0.214575 beta-lactamase_2500_S233L,beta-lactamase_2500_233,TEM-1,beta-lactamase_2500,P62593,0.214585,NO,233,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.886,-3.357,1.471,,0.016,E,B,0.27,-1.01,2.851,,77.62,BPO,-1.17267,0.361275,0.00311415,0.214585 kka2_1:2_G189I,kka2_1:2_189,Kka2,kka2_1:2,P00552,0.214596,NO,189,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.596,-4.264,3.668,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.295029,0.00253688,0.214596 kka2_1:1_E235I,kka2_1:1_235,Kka2,kka2_1:1,P00552,0.214746,NO,235,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.955,-4.019,2.064,,0.631,H,A,1.52,0.12,8.521,,65.53,OAH,-2.07267,0.520039,0.0102806,0.214746 kka2_1:8_V185Q,kka2_1:8_185,Kka2,kka2_1:8,P00552,0.214796,NO,185,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.045,-4.205,3.16,,0.058,E,B,1.48,-0.49,1.234,,46.97,HHH,-1.184,0.100394,0.00367031,0.214796 kka2_1:8_V185Q,kka2_1:8_185,Kka2,kka2_1:8,P00552,0.214796,NO,185,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.045,-4.205,3.16,,0.058,E,B,1.48,-0.49,1.234,,46.97,HHH,-1.184,0.100394,0.00367031,0.214796 kka2_1:4_A237D,kka2_1:4_237,Kka2,kka2_1:4,P00552,0.214814,NO,237,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.12,-2.999,0.879,,0.068,H,A,0.46,-0.71,2.444,,92.05,HHA,-2.10433,0.168804,0.012257,0.214814 Pab1_I157D,Pab1_157,Pab1,Pab1,P04147,0.214836,NO,157,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.623,-3.807,2.184,,,,,,,1.439,,79.72,BHH,-1.28667,0.175299,0.0018103,0.214836 beta-lactamase_625_I280G,beta-lactamase_625_280,TEM-1,beta-lactamase_625,P62593,0.214862,NO,280,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.213352,0.0530888,0.214862 kka2_1:4_L102F,kka2_1:4_102,Kka2,kka2_1:4,P00552,0.214881,NO,102,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.804,-3.669,2.865,,,T,A,0.55,-1.17,0.65,,42.42,AHH,-1.398,0.168804,0.00201332,0.214881 kka2_1:4_L170S,kka2_1:4_170,Kka2,kka2_1:4,P00552,0.214901,NO,170,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.28,-3.627,2.347,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.168804,0.00730791,0.214901 kka2_1:1_I141H,kka2_1:1_141,Kka2,kka2_1:1,P00552,0.214962,NO,141,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.495,-5.058,3.563,,0.068,H,A,0.48,-0.01,7.546,7.546,92.05,BHA,-1.689,0.520039,0.00744745,0.214962 kka2_1:1_L7D,kka2_1:1_7,Kka2,kka2_1:1,P00552,0.214965,NO,7,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.926,-2.297,0.371,,,,,,,18.934,18.934,71.59,OHB,-2.12333,0.520039,0.00269456,0.214965 beta-lactamase_625_G43W,beta-lactamase_625_43,TEM-1,beta-lactamase_625,P62593,0.214967,NO,43,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.62,-5.097,4.477,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.213352,0.00120151,0.214967 beta-lactamase_625_S201D,beta-lactamase_625_201,TEM-1,beta-lactamase_625,P62593,0.21497,NO,201,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.183,-3.453,2.27,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.213352,0.00198815,0.21497 kka2_1:4_L259Y,kka2_1:4_259,Kka2,kka2_1:4,P00552,0.214972,NO,259,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.088,-4.087,2.999,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.168804,0.0206964,0.214972 WW_domain_P202W,WW_domain_202,Yap65,WW_domain,P46937,0.214978,NO,202,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.4,-5.268,3.868,5.64207,,,,,,17.28,17.28,78.57,AOB,-1.436,0.153962,0.00212903,0.214978 beta-lactamase_39_C75R,beta-lactamase_39_75,TEM-1,beta-lactamase_39,P62593,0.214979,NO,75,C,R,CR,Special,PositiveCharge,5.07,6.34148,1.27148,180,121,174,53,108.5,173.4,64.9,-1.245,-4.065,2.82,,,H,A,0.46,-0.87,2.369,,50,HOO,-1.24333,0.0495842,0.0034616,0.214979 kka2_1:4_K50S,kka2_1:4_50,Kka2,kka2_1:4,P00552,0.214997,NO,50,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-0.833,-3.233,2.4,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.168804,0.00138626,0.214997 kka2_1:1_F206A,kka2_1:1_206,Kka2,kka2_1:1,P00552,0.215018,NO,206,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.349,-3.367,2.018,,0.006,E,B,0.58,-1.21,0.978,,63.64,OHH,-1.04,0.520039,0.00936868,0.215018 kka2_1:1_F206N,kka2_1:1_206,Kka2,kka2_1:1,P00552,0.215018,NO,206,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.349,-4.18,2.831,,0.006,E,B,0.58,-1.21,0.978,,63.64,OHH,-1.04,0.520039,0.00936868,0.215018 kka2_1:1_N195G,kka2_1:1_195,Kka2,kka2_1:1,P00552,0.215039,NO,195,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-0.836,-2.98,2.144,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.520039,0.00276134,0.215039 kka2_1:1_L193N,kka2_1:1_193,Kka2,kka2_1:1,P00552,0.215047,NO,193,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.983,-4.109,3.126,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.520039,0.00480179,0.215047 beta-lactamase_2500_L79N,beta-lactamase_2500_79,TEM-1,beta-lactamase_2500,P62593,0.215095,NO,79,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.842,-4.12,3.278,,0.007,H,A,0.55,-0.16,0.823,,50.35,HHP,-1.44333,0.361275,0.000947397,0.215095 beta-lactamase_2500_G154I,beta-lactamase_2500_154,TEM-1,beta-lactamase_2500,P62593,0.215113,NO,154,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.823,-4.173,3.35,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.361275,0.00180205,0.215113 beta-lactamase_156_R59P,beta-lactamase_156_59,TEM-1,beta-lactamase_156,P62593,0.215114,NO,59,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.345,-3.961,2.616,,0.329,S,L,1.2,-0.09,2.995,,73.08,HBO,-2.24267,0.111618,0.00318082,0.215114 kka2_1:1_G205M,kka2_1:1_205,Kka2,kka2_1:1,P00552,0.215146,NO,205,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.596,-4.958,4.362,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.520039,0.00221855,0.215146 kka2_1:8_L223F,kka2_1:8_223,Kka2,kka2_1:8,P00552,0.215155,NO,223,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.861,-3.69,2.829,,,H,A,1.59,-1.24,1.017,,50,HHH,-0.854333,0.100394,0.00253574,0.215155 kka2_1:8_L223F,kka2_1:8_223,Kka2,kka2_1:8,P00552,0.215155,NO,223,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.861,-3.69,2.829,,,H,A,1.59,-1.24,1.017,,50,HHH,-0.854333,0.100394,0.00253574,0.215155 kka2_1:2_R253Y,kka2_1:2_253,Kka2,kka2_1:2,P00552,0.215201,NO,253,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.356,-4.302,2.946,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.295029,0.0144195,0.215201 beta-lactamase_2500_R242D,beta-lactamase_2500_242,TEM-1,beta-lactamase_2500,P62593,0.215257,NO,242,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.361275,0.00452879,0.215257 beta-lactamase_2500_T107E,beta-lactamase_2500_107,TEM-1,beta-lactamase_2500,P62593,0.215324,NO,107,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.117,-3.43,2.313,,,G,A,0.22,-0.06,2.686,,67.83,HPA,-1.265,0.361275,0.00239347,0.215324 beta-lactamase_S104W,beta-lactamase_104,TEM-1,beta-lactamase,P62593,0.215358,NO,104,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.015,-5.359,4.344,4.92365,0.04,,b,0.82,0.57,4.02,,63.29,HPO,-1.05267,0.221079,0.00218083,0.215358 kka2_1:2_L174K,kka2_1:2_174,Kka2,kka2_1:2,P00552,0.215371,NO,174,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.952,-3.744,2.792,,,H,A,1.59,-0.31,8.521,,51.89,BHB,-2.08533,0.295029,0.00438501,0.215371 beta-lactamase_2500_N130V,beta-lactamase_2500_130,TEM-1,beta-lactamase_2500,P62593,0.215374,NO,130,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-0.798,-3.754,2.956,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.361275,0.000683376,0.215374 kka2_1:4_L223Q,kka2_1:4_223,Kka2,kka2_1:4,P00552,0.215379,NO,223,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.861,-4.235,3.374,,,H,A,1.59,-1.24,1.268,,50,HHH,-0.854333,0.168804,0.00253574,0.215379 beta-lactamase_156_E164W,beta-lactamase_156_164,TEM-1,beta-lactamase_156,P62593,0.215464,NO,164,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-0.948,-5.346,4.398,,0.011,T,B,1.04,-0.4,3.445,,64.69,HAO,-1.388,0.111618,0.00137286,0.215464 kka2_1:8_A34Y,kka2_1:8_34,Kka2,kka2_1:8,P00552,0.215514,NO,34,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.928,-4.223,3.295,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.100394,0.00343484,0.215514 kka2_1:8_A34Y,kka2_1:8_34,Kka2,kka2_1:8,P00552,0.215514,NO,34,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.928,-4.223,3.295,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.100394,0.00343484,0.215514 kka2_1:1_A150P,kka2_1:1_150,Kka2,kka2_1:1,P00552,0.215536,NO,150,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.949,-3.782,2.833,,0.544,T,A,0.46,1.34,2.333,,63.26,AHO,-1.272,0.520039,0.0045009,0.215536 kka2_1:1_R145W,kka2_1:1_145,Kka2,kka2_1:1,P00552,0.215575,NO,145,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.804,-3.243,1.439,,0.346,H,A,1.2,1.23,23.699,23.699,63.64,HBP,-1.88033,0.520039,0.00846663,0.215575 beta-lactamase_2500_L100N,beta-lactamase_2500_100,TEM-1,beta-lactamase_2500,P62593,0.215595,NO,100,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.218,-4.207,2.989,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.361275,0.00413885,0.215595 kka2_1:4_F171E,kka2_1:4_171,Kka2,kka2_1:4,P00552,0.215619,NO,171,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.326,-3.96,2.634,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.168804,0.00821426,0.215619 kka2_1:4_V97E,kka2_1:4_97,Kka2,kka2_1:4,P00552,0.215619,NO,97,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.453,-3.923,2.47,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.168804,0.00737869,0.215619 kka2_1:2_V214T,kka2_1:2_214,Kka2,kka2_1:2,P00552,0.215685,NO,214,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.261,-3.47,2.209,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.295029,0.00692782,0.215685 kka2_1:2_I228W,kka2_1:2_228,Kka2,kka2_1:2,P00552,0.215692,NO,228,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.142,-5.373,4.231,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.295029,0.00458834,0.215692 beta-lactamase_M115P,beta-lactamase_115,TEM-1,beta-lactamase,P62593,0.215726,NO,115,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.389,-4.034,2.645,4.89743,0.019,E,B,1.3,0.08,1.236,,69.58,OHP,-1.25433,0.221079,0.0034337,0.215726 kka2_1:1_A78T,kka2_1:1_78,Kka2,kka2_1:1,P00552,0.215729,NO,78,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.744,-3.425,1.681,,0.078,.,B,0.46,-0.53,0.206,,56.06,OHH,-1.863,0.520039,0.00457299,0.215729 kka2_1:1_E96R,kka2_1:1_96,Kka2,kka2_1:1,P00552,0.215758,NO,96,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.573,-2.69,0.117,,0.476,,B,1.52,-0.65,1.254,,71.59,OAH,-2.143,0.520039,0.00369441,0.215758 beta-lactamase_2500_F228E,beta-lactamase_2500_228,TEM-1,beta-lactamase_2500,P62593,0.215797,NO,228,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-2.342,-3.551,1.209,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.361275,0.0046669,0.215797 kka2_1:4_V186W,kka2_1:4_186,Kka2,kka2_1:4,P00552,0.215809,NO,186,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.011,-5.309,4.298,,,E,B,0.44,-0.61,0.679,,45.83,HHP,-1.10967,0.168804,0.00409703,0.215809 kka2_1:1_G201W,kka2_1:1_201,Kka2,kka2_1:1,P00552,0.215813,NO,201,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.56,-5.537,3.977,,0.149,T,l,0.29,-0.57,16.092,16.092,52.65,POB,-1.92233,0.520039,0.00820117,0.215813 kka2_1:1_D190T,kka2_1:1_190,Kka2,kka2_1:1,P00552,0.215915,NO,190,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.708,-3.45,2.742,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.520039,0.00247989,0.215915 beta-lactamase_39_D129A,beta-lactamase_39_129,TEM-1,beta-lactamase_39,P62593,0.215924,NO,129,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.816,-3.3,2.484,,,,B,0.75,-0.69,0.56,,34.97,PAP,-0.818,0.0495842,0.00109178,0.215924 kka2_1:1_G95T,kka2_1:1_95,Kka2,kka2_1:1,P00552,0.215956,NO,95,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-2.403,-1.849,-0.554,,0.126,E,B,0.29,-0.74,7.822,,71.59,HOA,-2.198,0.520039,0.00743616,0.215956 beta-lactamase_625_E164Y,beta-lactamase_625_164,TEM-1,beta-lactamase_625,P62593,0.216006,NO,164,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-0.948,-4.233,3.285,,0.011,T,B,1.04,-0.4,1.321,,64.69,HAO,-1.388,0.213352,0.00137286,0.216006 beta-lactamase_625_D155L,beta-lactamase_625_155,TEM-1,beta-lactamase_625,P62593,0.216108,NO,155,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.889,-3.807,2.918,,0.049,,B,0.75,-0.9,4.922,,64.69,OAB,-1.62267,0.213352,0.00135315,0.216108 beta-lactamase_156_I258P,beta-lactamase_156_258,TEM-1,beta-lactamase_156,P62593,0.21613,NO,258,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.111618,0.007931,0.21613 kka2_1:2_I115A,kka2_1:2_115,Kka2,kka2_1:2,P00552,0.21613,NO,115,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.606,-2.706,1.1,,0.105,H,A,0.48,-1.18,0.878,,65.53,PHH,-2.205,0.295029,0.00836567,0.21613 kka2_1:1_D156K,kka2_1:1_156,Kka2,kka2_1:1,P00552,0.216173,NO,156,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.696,-3.566,1.87,,0.884,T,A,0.75,1.87,1.044,,65.53,PAA,-1.765,0.520039,0.00926998,0.216173 beta-lactamase_156_A132D,beta-lactamase_156_132,TEM-1,beta-lactamase_156,P62593,0.216185,NO,132,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.9,-3.706,2.806,,,H,A,0.46,-0.93,10.621,,64.69,PHH,-1.138,0.111618,0.000962524,0.216185 beta-lactamase_2500_G234I,beta-lactamase_2500_234,TEM-1,beta-lactamase_2500,P62593,0.216229,NO,234,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.62,-4.235,3.615,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.361275,0.000889577,0.216229 kka2_1:4_A34F,kka2_1:4_34,Kka2,kka2_1:4,P00552,0.216261,NO,34,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.928,-4.127,3.199,,0.417,.,B,0.46,2.29,0.262,,52.27,AHH,-1.747,0.168804,0.00343484,0.216261 beta-lactamase_2500_S241R,beta-lactamase_2500_241,TEM-1,beta-lactamase_2500,P62593,0.216294,NO,241,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.433,-3.314,1.881,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.361275,0.00452736,0.216294 kka2_1:2_V185I,kka2_1:2_185,Kka2,kka2_1:2,P00552,0.216303,NO,185,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.045,-2.468,1.423,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.295029,0.00367031,0.216303 kka2_1:1_C31Y,kka2_1:1_31,Kka2,kka2_1:1,P00552,0.216323,NO,31,C,Y,CY,Special,Hydrophobic,5.07,5.66,0.59,194,121,181,60,108.5,193.6,85.1,-2.246,-4.264,2.018,,1.152,S,b,0.46,4.16,8.272,,63.26,OOP,-1.21533,0.520039,0.00681582,0.216323 beta-lactamase_625_A133E,beta-lactamase_625_133,TEM-1,beta-lactamase_625,P62593,0.216331,NO,133,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.186,-3.597,2.411,,,H,A,0.46,-0.86,0.373,,67.83,HHP,-0.988333,0.213352,0.00468022,0.216331 beta-lactamase_625_D177S,beta-lactamase_625_177,TEM-1,beta-lactamase_625,P62593,0.216373,NO,177,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.967,-3.186,2.219,,0.006,T,L,0.75,-1.02,1.333,,64.69,BAP,-0.873667,0.213352,0.000864022,0.216373 beta-lactamase_156_L205H,beta-lactamase_156_205,TEM-1,beta-lactamase_156,P62593,0.216398,NO,205,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.922,-4.828,3.906,,,H,A,0.55,-0.46,0.678,,42.31,PHH,-1.57767,0.111618,0.00255802,0.216398 beta-lactamase_625_M67W,beta-lactamase_625_67,TEM-1,beta-lactamase_625,P62593,0.216428,NO,67,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-2.231,-5.379,3.148,,0.006,G,P,0.55,-0.81,2.653,,65.03,HHP,-1.502,0.213352,0.00409753,0.216428 kka2_1:4_S32H,kka2_1:4_32,Kka2,kka2_1:4,P00552,0.216467,NO,32,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-0.804,-4.483,3.679,,0.768,S,b,0.27,3.75,,,,OPA,-1.74533,0.168804,0.00149998,0.216467 kka2_1:4_S32M,kka2_1:4_32,Kka2,kka2_1:4,P00552,0.216467,NO,32,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-0.804,-4.508,3.704,,0.768,S,b,0.27,3.75,,,,OPA,-1.74533,0.168804,0.00149998,0.216467 kka2_1:1_L241H,kka2_1:1_241,Kka2,kka2_1:1,P00552,0.216554,NO,241,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.158,-4.825,3.667,,0.08,H,A,0.55,-0.82,1.685,,63.26,HHH,-1.58533,0.520039,0.0117299,0.216554 kka2_1:4_G245W,kka2_1:4_245,Kka2,kka2_1:4,P00552,0.216575,NO,245,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.812,-5.257,4.445,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.168804,0.00683899,0.216575 kka2_1:1_A222H,kka2_1:1_222,Kka2,kka2_1:1,P00552,0.216606,NO,222,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.725,-4.708,3.983,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.520039,0.00207657,0.216606 kka2_1:2_A215I,kka2_1:2_215,Kka2,kka2_1:2,P00552,0.216623,NO,215,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.968,-3.723,2.755,,0.039,E,B,0.46,-0.59,2.137,,50.38,HHA,-1.00467,0.295029,0.00529129,0.216623 beta-lactamase_39_D177I,beta-lactamase_39_177,TEM-1,beta-lactamase_39,P62593,0.21663,NO,177,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.967,-4.048,3.081,,0.006,T,L,0.75,-1.02,3.536,,64.69,BAP,-0.873667,0.0495842,0.000864022,0.21663 beta-lactamase_G239E,beta-lactamase_239,TEM-1,beta-lactamase,P62593,0.216702,NO,239,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.819,-3.608,2.789,4.85529,0.115,T,l,0.77,-0.62,1.817,,42.31,BOP,-1.45267,0.221079,0.00213852,0.216702 kka2_1:1_P128V,kka2_1:1_128,Kka2,kka2_1:1,P00552,0.216707,NO,128,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.922,-2.023,0.101,,0.316,G,A,0.52,0.4,2.178,,56.06,AOH,-1.64733,0.520039,0.00774689,0.216707 kka2_1:4_I221H,kka2_1:4_221,Kka2,kka2_1:4,P00552,0.216741,NO,221,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.739,-5.027,3.288,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.168804,0.00945908,0.216741 kka2_1:2_R202W,kka2_1:2_202,Kka2,kka2_1:2,P00552,0.216751,NO,202,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.761,-5.54,3.779,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.295029,0.00696498,0.216751 beta-lactamase_R59V,beta-lactamase_59,TEM-1,beta-lactamase,P62593,0.216755,NO,59,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.345,-3.76,2.415,5.49837,0.329,S,L,0.68,-0.09,1.806,,73.08,HBO,-2.24267,0.221079,0.00318082,0.216755 kka2_1:2_T72I,kka2_1:2_72,Kka2,kka2_1:2,P00552,0.216803,NO,72,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.38,-4.117,1.737,,0.784,H,A,0.82,0.29,6.463,,65.53,HPP,-2.238,0.295029,0.00750756,0.216803 kka2_1:1_Q219W,kka2_1:1_219,Kka2,kka2_1:1,P00552,0.216827,NO,219,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-0.93,-5.169,4.239,,0.088,H,A,0.4,-0.85,1.917,,50,HPA,-1.05167,0.520039,0.00237913,0.216827 beta-lactamase_2500_P65F,beta-lactamase_2500_65,TEM-1,beta-lactamase_2500,P62593,0.216841,NO,65,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.894,-4.306,3.412,,0.098,E,B,0.52,-0.62,0.3,,40.56,HOH,-1.03233,0.361275,0.00152776,0.216841 kka2_1:1_N200Q,kka2_1:1_200,Kka2,kka2_1:1,P00552,0.216841,NO,200,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-2.446,-2.857,0.411,,0.756,T,L,0.61,-0.08,17.299,17.299,64.39,APO,-2.08,0.520039,0.00838549,0.216841 kka2_1:1_I221Y,kka2_1:1_221,Kka2,kka2_1:1,P00552,0.216897,NO,221,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.739,-4.012,2.273,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.520039,0.00945908,0.216897 beta-lactamase_I259S,beta-lactamase_259,TEM-1,beta-lactamase,P62593,0.216904,NO,259,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.522,-2.844,1.322,5.28457,,E,B,1,-0.8,1.24,,64.34,HHH,-1.53267,0.221079,0.0070773,0.216904 kka2_1:2_G233M,kka2_1:2_233,Kka2,kka2_1:2,P00552,0.216991,NO,233,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.748,-5.003,4.255,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.295029,0.00232366,0.216991 beta-lactamase_625_W288D,beta-lactamase_625_288,TEM-1,beta-lactamase_625,P62593,0.216994,NO,288,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,,,,,,,,,,,,,BHO,,0.213352,,0.216994 kka2_1:1_F203Y,kka2_1:1_203,Kka2,kka2_1:1,P00552,0.216996,NO,203,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-0.911,-3.189,2.278,,0.26,E,B,0.58,-0.92,7.323,,63.64,BHP,-1.34167,0.520039,0.00318738,0.216996 beta-lactamase_156_T158P,beta-lactamase_156_158,TEM-1,beta-lactamase_156,P62593,0.217086,NO,158,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.116,-2.676,1.56,,0.036,,B,0.22,-0.85,3.771,,69.58,HPB,-1.269,0.111618,0.00341825,0.217086 beta-lactamase_625_I277E,beta-lactamase_625_277,TEM-1,beta-lactamase_625,P62593,0.217134,NO,277,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.869,-4.006,2.137,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.213352,0.0169305,0.217134 beta-lactamase_0_A123H,beta-lactamase_0_123,TEM-1,beta-lactamase_0,P62593,0.217215,NO,123,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.834,-4.729,3.895,,0.039,H,A,0.46,-0.72,1.308,,41.26,PHH,-1.47367,0.0500837,0.0010157,0.217215 beta-lactamase_2500_A230E,beta-lactamase_2500_230,TEM-1,beta-lactamase_2500,P62593,0.217292,NO,230,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.154,-3.566,2.412,,0.01,E,B,0.46,-1.17,1.171,,50,HHA,-1.079,0.361275,0.00516841,0.217292 kka2_1:8_G205W,kka2_1:8_205,Kka2,kka2_1:8,P00552,0.217301,NO,205,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.596,-5.126,4.53,,,E,b,0.75,-1.05,,,,POH,-1.09933,0.100394,0.00221855,0.217301 kka2_1:8_G205W,kka2_1:8_205,Kka2,kka2_1:8,P00552,0.217301,NO,205,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.596,-5.126,4.53,,,E,b,0.75,-1.05,,,,POH,-1.09933,0.100394,0.00221855,0.217301 kka2_1:8_G233Y,kka2_1:8_233,Kka2,kka2_1:8,P00552,0.217301,NO,233,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.748,-4.46,3.712,,0.172,,b,0.75,-0.27,1.134,,49.24,HOO,-1.72067,0.100394,0.00232366,0.217301 kka2_1:8_G233Y,kka2_1:8_233,Kka2,kka2_1:8,P00552,0.217301,NO,233,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.748,-4.46,3.712,,0.172,,b,0.75,-0.27,1.134,,49.24,HOO,-1.72067,0.100394,0.00232366,0.217301 beta-lactamase_625_S128W,beta-lactamase_625_128,TEM-1,beta-lactamase_625,P62593,0.217335,NO,128,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-0.84,-5.322,4.482,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.213352,0.00071483,0.217335 kka2_1:2_A191Q,kka2_1:2_191,Kka2,kka2_1:2,P00552,0.217342,NO,191,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.831,-3.962,3.131,,,.,b,0.46,-0.94,2.046,,50,AHO,-0.868667,0.295029,0.00338807,0.217342 kka2_1:4_L241N,kka2_1:4_241,Kka2,kka2_1:4,P00552,0.217392,NO,241,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.158,-4.222,3.064,,0.08,H,A,0.55,-0.82,1.598,,63.26,HHH,-1.58533,0.168804,0.0117299,0.217392 kka2_1:1_N200M,kka2_1:1_200,Kka2,kka2_1:1,P00552,0.217407,NO,200,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-2.446,-4.957,2.511,,0.756,T,L,0.61,-0.08,17.299,17.299,64.39,APO,-2.08,0.520039,0.00838549,0.217407 beta-lactamase_39_I277P,beta-lactamase_39_277,TEM-1,beta-lactamase_39,P62593,0.217433,NO,277,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.0495842,0.0169305,0.217433 kka2_1:1_L103I,kka2_1:1_103,Kka2,kka2_1:1,P00552,0.217444,NO,103,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-2.362,-3.505,1.143,,0.394,T,A,0.55,-0.99,4.121,,63.64,HHP,-1.534,0.520039,0.00574792,0.217444 Pab1_K156D,Pab1_156,Pab1,Pab1,P04147,0.217473,NO,156,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.083,-3.286,2.203,,0.406,E,B,1.82,-0.26,,,,PBH,-1.58167,0.175299,0.000316767,0.217473 E1_Ubiquitin_G76R,E1_Ubiquitin_76,Uba1,E1_Ubiquitin,P0CG63,0.217507,NO,76,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.999,-3.854,2.855,,0.23,,B,0.75,0.08,1.702,,83.73,OOO,-0.999,0.18783,0.00125575,0.217507 kka2_1:1_A144D,kka2_1:1_144,Kka2,kka2_1:1,P00552,0.21752,NO,144,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.859,-3.804,2.945,,,H,A,0.46,0.21,0.842,,52.65,BHB,-1.72933,0.520039,0.00231095,0.21752 beta-lactamase_625_I261S,beta-lactamase_625_261,TEM-1,beta-lactamase_625,P62593,0.217559,NO,261,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.213352,0.0123091,0.217559 kka2_1:1_A150D,kka2_1:1_150,Kka2,kka2_1:1,P00552,0.217612,NO,150,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.949,-3.619,2.67,,0.544,T,A,0.46,1.34,2.333,,63.26,AHO,-1.272,0.520039,0.0045009,0.217612 kka2_1:2_P45F,kka2_1:2_45,Kka2,kka2_1:2,P00552,0.217619,NO,45,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.774,-4.506,2.732,,0.669,,B,0.52,-0.76,4.882,,71.59,BOH,-2.152,0.295029,0.00590481,0.217619 beta-lactamase_625_C121H,beta-lactamase_625_121,TEM-1,beta-lactamase_625,P62593,0.217648,NO,121,C,H,CH,Special,PositiveCharge,5.07,7.59,2.52,174,121,155,34,108.5,153.2,44.7,-0.953,-4.827,3.874,,,H,A,0.46,-0.81,1.143,,63.29,HOP,-1.46767,0.213352,0.000744322,0.217648 kka2_1:8_F203A,kka2_1:8_203,Kka2,kka2_1:8,P00552,0.217657,NO,203,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-0.911,-3.329,2.418,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.100394,0.00318738,0.217657 kka2_1:8_F203A,kka2_1:8_203,Kka2,kka2_1:8,P00552,0.217657,NO,203,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-0.911,-3.329,2.418,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.100394,0.00318738,0.217657 beta-lactamase_2500_A123F,beta-lactamase_2500_123,TEM-1,beta-lactamase_2500,P62593,0.217659,NO,123,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.834,-4.065,3.231,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.361275,0.0010157,0.217659 beta-lactamase_625_T69Y,beta-lactamase_625_69,TEM-1,beta-lactamase_625,P62593,0.217665,NO,69,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-0.973,-4.223,3.25,,,G,A,0.22,-1.24,2.716,,93.01,PPH,-1.01833,0.213352,0.00127498,0.217665 beta-lactamase_2500_L120W,beta-lactamase_2500_120,TEM-1,beta-lactamase_2500,P62593,0.217724,NO,120,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.044,-5.142,4.098,,,H,A,0.55,-1.13,2.48,,64.69,AHO,-1.13633,0.361275,0.00143563,0.217724 kka2_1:1_C77E,kka2_1:1_77,Kka2,kka2_1:1,P00552,0.217727,NO,77,C,E,CE,Special,negativeCharge,5.07,3.22,-1.85,170,121,147,26,108.5,138.4,29.9,-1.477,-3.891,2.414,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.520039,0.00441216,0.217727 Ubiquitin_G10P,Ubiquitin_10,Uba1,Ubiquitin,P0CG48,0.217742,NO,10,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.396,-3.924,2.528,5.29806,0.115,S,l,,0.2,,,,POB,-1.38633,0.205827,0.000748953,0.217742 Ubiquitin_G75A,Ubiquitin_75,Uba1,Ubiquitin,P0CG48,0.217742,NO,75,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.613,-2.434,0.821,5.44099,0.552,T,A,0.73,0.9,4.017,,34.31,BOO,-1.66767,0.205827,0.000712673,0.217742 Ubiquitin_L15G,Ubiquitin_15,Uba1,Ubiquitin,P0CG48,0.217742,NO,15,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.082,-3.792,2.71,5.14718,0.029,E,B,1.16,-0.53,0.936,,38.69,PHA,-1.40833,0.205827,0.000519738,0.217742 Ubiquitin_Q2P,Ubiquitin_2,Uba1,Ubiquitin,P0CG48,0.217742,NO,2,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-1.7,-3.858,2.158,4.89203,0.475,E,B,,0.1,,,,OPH,-1.551,0.205827,0.00085006,0.217742 Ubiquitin_R42L,Ubiquitin_42,Uba1,Ubiquitin,P0CG48,0.217742,NO,42,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.571,-3.348,1.777,5.07805,0.244,E,B,0.68,-0.54,1.976,,72.85,PBH,-1.38967,0.205827,0.000622265,0.217742 Ubiquitin_V70Q,Ubiquitin_70,Uba1,Ubiquitin,P0CG48,0.217742,NO,70,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.874,-3.14,1.266,5.29728,0.05,E,B,0.96,-0.97,2.363,,34.31,HHH,-1.65533,0.205827,0.00106871,0.217742 beta-lactamase_156_T158W,beta-lactamase_156_158,TEM-1,beta-lactamase_156,P62593,0.217743,NO,158,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.116,-5.268,4.152,,0.036,,B,0.22,-0.85,3.771,,69.58,HPB,-1.269,0.111618,0.00341825,0.217743 beta-lactamase_156_A230N,beta-lactamase_156_230,TEM-1,beta-lactamase_156,P62593,0.217751,NO,230,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.154,-3.731,2.577,,0.01,E,B,0.46,-1.17,2.179,,50,HHA,-1.079,0.111618,0.00516841,0.217751 beta-lactamase_2500_F64Q,beta-lactamase_2500_64,TEM-1,beta-lactamase_2500,P62593,0.217824,NO,64,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-0.841,-4.349,3.508,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.361275,0.000947691,0.217824 kka2_1:1_L260F,kka2_1:1_260,Kka2,kka2_1:1,P00552,0.217851,NO,260,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.741,-3.645,2.904,,0.022,H,A,0.55,-0.52,,,,HHA,-0.845667,0.520039,0.0233782,0.217851 beta-lactamase_2500_I277Q,beta-lactamase_2500_277,TEM-1,beta-lactamase_2500,P62593,0.217945,NO,277,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.361275,0.0169305,0.217945 kka2_1:2_A117C,kka2_1:2_117,Kka2,kka2_1:2,P00552,0.217946,NO,117,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.828,-4.504,3.676,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.295029,0.00282984,0.217946 kka2_1:2_V113W,kka2_1:2_113,Kka2,kka2_1:2,P00552,0.217951,NO,113,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.233,-5.432,4.199,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.295029,0.00650191,0.217951 kka2_1:1_D156R,kka2_1:1_156,Kka2,kka2_1:1,P00552,0.217999,NO,156,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.696,-3.967,2.271,,0.884,T,A,0.75,1.87,1.044,,65.53,PAA,-1.765,0.520039,0.00926998,0.217999 kka2_1:2_F206I,kka2_1:2_206,Kka2,kka2_1:2,P00552,0.218001,NO,206,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.349,-3.398,2.049,,0.006,E,B,0.58,-1.21,0.978,,63.64,OHH,-1.04,0.295029,0.00936868,0.218001 kka2_1:8_V185W,kka2_1:8_185,Kka2,kka2_1:8,P00552,0.218013,NO,185,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.045,-5.383,4.338,,0.058,E,B,1.48,-0.49,1.234,,46.97,HHH,-1.184,0.100394,0.00367031,0.218013 kka2_1:8_V185W,kka2_1:8_185,Kka2,kka2_1:8,P00552,0.218013,NO,185,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.045,-5.383,4.338,,0.058,E,B,1.48,-0.49,1.234,,46.97,HHH,-1.184,0.100394,0.00367031,0.218013 beta-lactamase_156_S233E,beta-lactamase_156_233,TEM-1,beta-lactamase_156,P62593,0.218047,NO,233,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.886,-3.479,1.593,,0.016,E,B,0.27,-1.01,4.111,,77.62,BPO,-1.17267,0.111618,0.00311415,0.218047 beta-lactamase_625_T179G,beta-lactamase_625_179,TEM-1,beta-lactamase_625,P62593,0.218056,NO,179,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.085,-3.296,2.211,,,E,B,0.22,-1.38,0.367,,73.08,PPH,-1.557,0.213352,0.00226045,0.218056 kka2_1:4_A222L,kka2_1:4_222,Kka2,kka2_1:4,P00552,0.218067,NO,222,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.725,-3.161,2.436,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.168804,0.00207657,0.218067 kka2_1:2_V113M,kka2_1:2_113,Kka2,kka2_1:2,P00552,0.218082,NO,113,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.233,-3.136,1.903,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.295029,0.00650191,0.218082 beta-lactamase_625_T178R,beta-lactamase_625_178,TEM-1,beta-lactamase_625,P62593,0.218105,NO,178,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-0.791,-3.708,2.917,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.213352,0.000684366,0.218105 beta-lactamase_2500_M184N,beta-lactamase_2500_184,TEM-1,beta-lactamase_2500,P62593,0.218108,NO,184,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.593,-4.028,2.435,,,H,A,0.55,-0.87,2.893,,62.94,HHH,-1.41,0.361275,0.00356019,0.218108 beta-lactamase_2500_Y44W,beta-lactamase_2500_44,TEM-1,beta-lactamase_2500,P62593,0.218123,NO,44,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-2.547,-5.1,2.553,,,E,B,0.21,-0.45,2.184,,73.78,OHH,-1.86267,0.361275,0.00426364,0.218123 kka2_1:8_R226E,kka2_1:8_226,Kka2,kka2_1:8,P00552,0.218191,NO,226,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.392,-3.484,2.092,,0.222,H,A,0.16,-0.71,3.818,,56.06,PBA,-1.84767,0.100394,0.0108032,0.218191 kka2_1:8_R226E,kka2_1:8_226,Kka2,kka2_1:8,P00552,0.218191,NO,226,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.392,-3.484,2.092,,0.222,H,A,0.16,-0.71,3.818,,56.06,PBA,-1.84767,0.100394,0.0108032,0.218191 beta-lactamase_I256S,beta-lactamase_256,TEM-1,beta-lactamase,P62593,0.218232,NO,256,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.621,-3.676,2.055,5.3196,,E,B,1,-0.84,1.615,,73.08,BHH,-1.80667,0.221079,0.00710634,0.218232 kka2_1:1_A229F,kka2_1:1_229,Kka2,kka2_1:1,P00552,0.218239,NO,229,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.739,-4.384,2.645,,0.32,H,A,0.46,-0.7,6.549,,63.64,HHA,-1.851,0.520039,0.00942138,0.218239 kka2_1:2_I228G,kka2_1:2_228,Kka2,kka2_1:2,P00552,0.218285,NO,228,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.142,-3.869,2.727,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.295029,0.00458834,0.218285 beta-lactamase_625_S104Q,beta-lactamase_625_104,TEM-1,beta-lactamase_625,P62593,0.218339,NO,104,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.015,-3.815,2.8,,0.04,,b,0.27,0.57,1.76,,63.29,HPO,-1.05267,0.213352,0.00218083,0.218339 kka2_1:1_I207Y,kka2_1:1_207,Kka2,kka2_1:1,P00552,0.218339,NO,207,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.175,-4.053,2.878,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.520039,0.00611824,0.218339 kka2_1:1_W236N,kka2_1:1_236,Kka2,kka2_1:1,P00552,0.218339,NO,236,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-1.363,-4.289,2.926,,0.303,H,A,1.51,-0.76,12.263,12.263,48.48,AHH,-1.81267,0.520039,0.0088796,0.218339 beta-lactamase_625_I244S,beta-lactamase_625_244,TEM-1,beta-lactamase_625,P62593,0.218431,NO,244,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.555,-3.602,2.047,,,E,B,0.48,-0.84,2.061,,77.62,OHH,-1.385,0.213352,0.00605379,0.218431 kka2_1:1_P76D,kka2_1:1_76,Kka2,kka2_1:1,P00552,0.218443,NO,76,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.449,-2.541,1.092,,0.331,.,B,0.52,-0.41,0.345,,63.64,HOO,-1.662,0.520039,0.00625685,0.218443 kka2_1:1_H162F,kka2_1:1_162,Kka2,kka2_1:1,P00552,0.21845,NO,162,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-2.319,-4.187,1.868,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.520039,0.00616145,0.21845 beta-lactamase_625_S68W,beta-lactamase_625_68,TEM-1,beta-lactamase_625,P62593,0.218487,NO,68,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-0.913,-5.371,4.458,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.213352,0.000800065,0.218487 beta-lactamase_625_T158D,beta-lactamase_625_158,TEM-1,beta-lactamase_625,P62593,0.218534,NO,158,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.116,-3.478,2.362,,0.036,,B,0.22,-0.85,3.771,,69.58,HPB,-1.269,0.213352,0.00341825,0.218534 kka2_1:8_A224W,kka2_1:8_224,Kka2,kka2_1:8,P00552,0.218546,NO,224,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.977,-5.377,4.4,,,H,A,0.46,-1.26,0.357,,63.64,HHP,-1.41033,0.100394,0.00352047,0.218546 kka2_1:8_A224W,kka2_1:8_224,Kka2,kka2_1:8,P00552,0.218546,NO,224,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.977,-5.377,4.4,,,H,A,0.46,-1.26,0.357,,63.64,HHP,-1.41033,0.100394,0.00352047,0.218546 beta-lactamase_156_L191D,beta-lactamase_156_191,TEM-1,beta-lactamase_156,P62593,0.218589,NO,191,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.087,-4.092,3.005,,,H,A,0.55,0.09,1.372,,63.29,BHH,-1.445,0.111618,0.00263549,0.218589 kka2_1:4_S105F,kka2_1:4_105,Kka2,kka2_1:4,P00552,0.21862,NO,105,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.945,-4.371,2.426,,0.056,S,B,0.77,-1.04,3.442,,65.53,PPB,-2.17033,0.168804,0.00847233,0.21862 kka2_1:4_I207D,kka2_1:4_207,Kka2,kka2_1:4,P00552,0.218676,NO,207,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.175,-4.057,2.882,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.168804,0.00611824,0.218676 kka2_1:8_P109I,kka2_1:8_109,Kka2,kka2_1:8,P00552,0.218724,NO,109,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.412,-3.963,2.551,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.100394,0.0070929,0.218724 kka2_1:8_P109I,kka2_1:8_109,Kka2,kka2_1:8,P00552,0.218724,NO,109,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.412,-3.963,2.551,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.100394,0.0070929,0.218724 kka2_1:1_D208P,kka2_1:1_208,Kka2,kka2_1:1,P00552,0.218733,NO,208,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.708,-3.683,2.975,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.520039,0.00212588,0.218733 kka2_1:1_V97F,kka2_1:1_97,Kka2,kka2_1:1,P00552,0.21876,NO,97,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.453,-3.895,2.442,,0.083,,B,1.48,-0.83,13.576,13.576,53.03,AHO,-1.85067,0.520039,0.00737869,0.21876 kka2_1:2_Y257P,kka2_1:2_257,Kka2,kka2_1:2,P00552,0.21877,NO,257,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-1.064,-4.26,3.196,,0.022,H,A,0.21,-0.88,0.833,,52.65,HHB,-1.39333,0.295029,0.0148191,0.21877 beta-lactamase_2500_C121D,beta-lactamase_2500_121,TEM-1,beta-lactamase_2500,P62593,0.218798,NO,121,C,D,CD,Special,negativeCharge,5.07,5.0516,-0.0184,154,121,133,12,108.5,111.1,2.6,-0.953,-3.916,2.963,,,H,A,0.46,-0.81,1.174,,63.29,HOP,-1.46767,0.361275,0.000744322,0.218798 kka2_1:1_T73R,kka2_1:1_73,Kka2,kka2_1:1,P00552,0.218798,NO,73,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.51,-2.766,0.256,,0.309,H,A,0.22,0.35,4.126,,56.06,PPO,-2.02333,0.520039,0.00628605,0.218798 kka2_1:2_A129P,kka2_1:2_129,Kka2,kka2_1:2,P00552,0.218851,NO,129,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.656,-4.009,2.353,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.295029,0.00726862,0.218851 kka2_1:4_L94N,kka2_1:4_94,Kka2,kka2_1:4,P00552,0.218894,NO,94,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.618,-4.108,2.49,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.168804,0.00520888,0.218894 kka2_1:1_P76Y,kka2_1:1_76,Kka2,kka2_1:1,P00552,0.218897,NO,76,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.449,-4.443,2.994,,0.331,.,B,0.52,-0.41,0.345,,63.64,HOO,-1.662,0.520039,0.00625685,0.218897 kka2_1:4_L212D,kka2_1:4_212,Kka2,kka2_1:4,P00552,0.218916,NO,212,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.904,-4.134,3.23,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.168804,0.0031426,0.218916 beta-lactamase_625_M184H,beta-lactamase_625_184,TEM-1,beta-lactamase_625,P62593,0.218965,NO,184,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.593,-4.818,3.225,,,H,A,0.55,-0.87,2.765,,62.94,HHH,-1.41,0.213352,0.00356019,0.218965 kka2_1:2_F264I,kka2_1:2_264,Kka2,kka2_1:2,P00552,0.218996,NO,264,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.02,-3.433,2.413,,0.296,.,?,0.58,0.02,2.303,,71.59,HHNA,-0.9655,0.295029,,0.218996 kka2_1:1_A108R,kka2_1:1_108,Kka2,kka2_1:1,P00552,0.219052,NO,108,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.061,-4.036,1.975,,0.243,.,B,0.46,-1.34,3.156,,71.59,HHO,-1.57033,0.520039,0.00751209,0.219052 kka2_1:8_A222H,kka2_1:8_222,Kka2,kka2_1:8,P00552,0.219079,NO,222,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.725,-4.708,3.983,,,H,A,1.04,-1.21,,,,HHH,-1.10833,0.100394,0.00207657,0.219079 kka2_1:8_A222H,kka2_1:8_222,Kka2,kka2_1:8,P00552,0.219079,NO,222,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.725,-4.708,3.983,,,H,A,1.04,-1.21,,,,HHH,-1.10833,0.100394,0.00207657,0.219079 kka2_1:1_D227F,kka2_1:1_227,Kka2,kka2_1:1,P00552,0.219105,NO,227,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.758,-4.199,2.441,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.520039,0.00745029,0.219105 kka2_1:2_L47E,kka2_1:2_47,Kka2,kka2_1:2,P00552,0.219139,NO,47,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.265,-3.747,2.482,,0.139,E,B,0.55,-0.86,2.369,,63.26,HHH,-1.77933,0.295029,0.00509386,0.219139 kka2_1:1_F264D,kka2_1:1_264,Kka2,kka2_1:1,P00552,0.21917,NO,264,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.02,-4.038,3.018,,0.296,.,?,0.58,0.02,2.303,,71.59,HHNA,-0.9655,0.520039,,0.21917 PSD95pdz3_G324F,PSD95pdz3_324,PSD95pdz3,PSD95pdz3,P31016,0.21923,NO,324,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.008,-3.974,2.966,4.98881,,,,,10.4525,,,,HOH,-1.293,0.0758425,0.00103462,0.21923 beta-lactamase_625_R202P,beta-lactamase_625_202,TEM-1,beta-lactamase_625,P62593,0.219239,NO,202,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.292,-3.859,2.567,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.213352,0.00321899,0.219239 kka2_1:4_R239P,kka2_1:4_239,Kka2,kka2_1:4,P00552,0.219268,NO,239,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.949,-1.624,-1.325,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.168804,0.00835326,0.219268 kka2_1:1_T28W,kka2_1:1_28,Kka2,kka2_1:1,P00552,0.219303,NO,28,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.883,-5.518,3.635,,0.353,S,B,0.22,2.02,1.12,,63.64,PPH,-1.74467,0.520039,0.00743084,0.219303 beta-lactamase_2500_I245R,beta-lactamase_2500_245,TEM-1,beta-lactamase_2500,P62593,0.219306,NO,245,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.361275,0.00391032,0.219306 kka2_1:1_Q219S,kka2_1:1_219,Kka2,kka2_1:1,P00552,0.219338,NO,219,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-0.93,-3.233,2.303,,0.088,H,A,0.4,-0.85,1.917,,50,HPA,-1.05167,0.520039,0.00237913,0.219338 beta-lactamase_625_D161R,beta-lactamase_625_161,TEM-1,beta-lactamase_625,P62593,0.219563,NO,161,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.891,-3.902,3.011,,0.341,,A,0.75,-0.52,4.655,,61.19,HAB,-0.961333,0.213352,0.000897697,0.219563 kka2_1:1_L94N,kka2_1:1_94,Kka2,kka2_1:1,P00552,0.219565,NO,94,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.618,-4.108,2.49,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.520039,0.00520888,0.219565 kka2_1:1_A224H,kka2_1:1_224,Kka2,kka2_1:1,P00552,0.219636,NO,224,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.977,-4.809,3.832,,,H,A,0.46,-1.26,1.725,,63.64,HHP,-1.41033,0.520039,0.00352047,0.219636 beta-lactamase_156_K232N,beta-lactamase_156_232,TEM-1,beta-lactamase_156,P62593,0.219688,NO,232,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.012,-3.49,2.478,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.111618,0.00313441,0.219688 kka2_1:4_G213D,kka2_1:4_213,Kka2,kka2_1:4,P00552,0.219823,NO,213,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.596,-3.497,2.901,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.168804,0.00187654,0.219823 beta-lactamase_2500_L74E,beta-lactamase_2500_74,TEM-1,beta-lactamase_2500,P62593,0.219826,NO,74,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.296,-3.786,2.49,,,H,A,0.55,-0.91,0.746,,50,HHO,-1.34933,0.361275,0.00493255,0.219826 kka2_1:1_I115A,kka2_1:1_115,Kka2,kka2_1:1,P00552,0.219835,NO,115,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.606,-2.706,1.1,,0.105,H,A,0.48,-1.18,0.878,,65.53,PHH,-2.205,0.520039,0.00836567,0.219835 beta-lactamase_156_L74F,beta-lactamase_156_74,TEM-1,beta-lactamase_156,P62593,0.219841,NO,74,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.296,-3.848,2.552,,,H,A,0.55,-0.91,0.746,,50,HHO,-1.34933,0.111618,0.00493255,0.219841 kka2_1:1_R18V,kka2_1:1_18,Kka2,kka2_1:1,P00552,0.21992,NO,18,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.055,-3.089,1.034,,0.474,T,A,1.2,0.54,11.422,11.422,71.59,ABH,-1.821,0.520039,0.00724065,0.21992 beta-lactamase_156_L192D,beta-lactamase_156_192,TEM-1,beta-lactamase_156,P62593,0.21995,NO,192,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.254,-4.104,2.85,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.111618,0.00558728,0.21995 beta-lactamase_2500_A34K,beta-lactamase_2500_34,TEM-1,beta-lactamase_2500,P62593,0.219995,NO,34,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.059,-3.736,1.677,,,H,A,0.46,-0.54,2.921,,73.78,AHA,-1.74967,0.361275,0.00407913,0.219995 kka2_1:1_F264A,kka2_1:1_264,Kka2,kka2_1:1,P00552,0.220005,NO,264,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.02,-3.385,2.365,,0.296,.,?,0.58,0.02,2.303,,71.59,HHNA,-0.9655,0.520039,,0.220005 beta-lactamase_G142F,beta-lactamase_142,TEM-1,beta-lactamase,P62593,0.220012,NO,142,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.707,-4.29,3.583,4.55474,0.034,,p,0.77,-0.64,1.947,,64.69,OOO,-0.834,0.221079,0.00060149,0.220012 beta-lactamase_G76Q,beta-lactamase_76,TEM-1,beta-lactamase,P62593,0.220012,NO,76,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.189,-4.074,2.885,4.73862,,H,A,2.05,-0.67,3.059,,67.83,OOH,-1.22267,0.221079,0.00476637,0.220012 PSD95pdz3_L353D,PSD95pdz3_353,PSD95pdz3,PSD95pdz3,P31016,0.22004,NO,353,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.347,-3.825,2.478,5.81136,,,,,17.3525,,,,AHB,-1.50533,0.0758425,0.000664742,0.22004 beta-lactamase_2500_F64H,beta-lactamase_2500_64,TEM-1,beta-lactamase_2500,P62593,0.220046,NO,64,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-0.841,-4.455,3.614,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.361275,0.000947691,0.220046 beta-lactamase_625_N134F,beta-lactamase_625_134,TEM-1,beta-lactamase_625,P62593,0.220066,NO,134,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-0.879,-4.318,3.439,,0.138,H,A,0.61,-0.6,3.776,,53.15,HPH,-1.02233,0.213352,0.000644786,0.220066 beta-lactamase_2500_Y95N,beta-lactamase_2500_95,TEM-1,beta-lactamase_2500,P62593,0.220077,NO,95,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-1.715,-4.149,2.434,,0.122,,b,0.21,-0.37,2.914,,77.62,BHP,-2.16167,0.361275,0.00479449,0.220077 beta-lactamase_2500_L120D,beta-lactamase_2500_120,TEM-1,beta-lactamase_2500,P62593,0.220093,NO,120,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.044,-4.076,3.032,,,H,A,0.55,-1.13,2.48,,64.69,AHO,-1.13633,0.361275,0.00143563,0.220093 kka2_1:2_G151I,kka2_1:2_151,Kka2,kka2_1:2,P00552,0.220134,NO,151,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.873,-4.249,3.376,,0.678,T,l,0.29,1.36,1.357,,49.62,HOH,-1.11433,0.295029,0.00339918,0.220134 kka2_1:8_F264N,kka2_1:8_264,Kka2,kka2_1:8,P00552,0.220141,NO,264,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.02,-4.176,3.156,,0.296,,?,1.62,0.02,1.553,,71.59,HHO,-0.9655,0.100394,,0.220141 kka2_1:8_F264N,kka2_1:8_264,Kka2,kka2_1:8,P00552,0.220141,NO,264,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.02,-4.176,3.156,,0.296,,?,1.62,0.02,1.553,,71.59,HHO,-0.9655,0.100394,,0.220141 kka2_1:8_Y22N,kka2_1:8_22,Kka2,kka2_1:8,P00552,0.220141,NO,22,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-1.583,-3.898,2.315,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.100394,0.00598977,0.220141 kka2_1:8_Y22N,kka2_1:8_22,Kka2,kka2_1:8,P00552,0.220141,NO,22,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-1.583,-3.898,2.315,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.100394,0.00598977,0.220141 kka2_1:8_Y22Q,kka2_1:8_22,Kka2,kka2_1:8,P00552,0.220141,NO,22,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-1.583,-4.105,2.522,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.100394,0.00598977,0.220141 kka2_1:8_Y22Q,kka2_1:8_22,Kka2,kka2_1:8,P00552,0.220141,NO,22,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-1.583,-4.105,2.522,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.100394,0.00598977,0.220141 kka2_1:1_G189I,kka2_1:1_189,Kka2,kka2_1:1,P00552,0.220232,NO,189,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.596,-4.264,3.668,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.520039,0.00253688,0.220232 kka2_1:1_G151K,kka2_1:1_151,Kka2,kka2_1:1,P00552,0.220296,NO,151,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.873,-3.594,2.721,,0.678,T,l,0.29,1.36,0.226,,49.62,HOH,-1.11433,0.520039,0.00339918,0.220296 kka2_1:4_D261T,kka2_1:4_261,Kka2,kka2_1:4,P00552,0.220307,NO,261,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.708,-3.45,2.742,,0.146,G,A,0.75,-0.33,,,,HAA,-0.759333,0.168804,0.0224846,0.220307 beta-lactamase_Y95N,beta-lactamase_95,TEM-1,beta-lactamase,P62593,0.220444,NO,95,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-1.715,-4.149,2.434,5.67068,0.122,,b,0.96,-0.37,2.341,,77.62,BHP,-2.16167,0.221079,0.00479449,0.220444 kka2_1:4_L158I,kka2_1:4_158,Kka2,kka2_1:4,P00552,0.220478,NO,158,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.947,-3.293,1.346,,0.095,,B,1.59,0.77,7.588,,63.64,AHA,-1.25333,0.168804,0.00529068,0.220478 beta-lactamase_625_G236M,beta-lactamase_625_236,TEM-1,beta-lactamase_625,P62593,0.220489,NO,236,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.784,-4.869,4.085,,0.241,,b,0.29,-0.59,3.506,,64.69,HOO,-1.025,0.213352,0.00162372,0.220489 beta-lactamase_156_G236K,beta-lactamase_156_236,TEM-1,beta-lactamase_156,P62593,0.220539,NO,236,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.784,-3.651,2.867,,0.241,,b,0.29,-0.59,1.883,,64.69,HOO,-1.025,0.111618,0.00162372,0.220539 beta-lactamase_2500_A247P,beta-lactamase_2500_247,TEM-1,beta-lactamase_2500,P62593,0.220543,NO,247,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.361275,0.00611275,0.220543 kka2_1:2_G210Y,kka2_1:2_210,Kka2,kka2_1:2,P00552,0.220544,NO,210,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.095,-4.42,3.325,,0.103,T,A,0.29,-0.62,0.271,,50,OOB,-0.966667,0.295029,0.00598378,0.220544 kka2_1:8_D208R,kka2_1:8_208,Kka2,kka2_1:8,P00552,0.22067,NO,208,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.708,-3.961,3.253,,0.36,,l,0.29,-1.01,,,,HAO,-0.929667,0.100394,0.00212588,0.22067 kka2_1:8_D208R,kka2_1:8_208,Kka2,kka2_1:8,P00552,0.22067,NO,208,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.708,-3.961,3.253,,0.36,,l,0.29,-1.01,,,,HAO,-0.929667,0.100394,0.00212588,0.22067 kka2_1:2_S114D,kka2_1:2_114,Kka2,kka2_1:2,P00552,0.220671,NO,114,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.527,-2.691,0.164,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.295029,0.00705262,0.220671 beta-lactamase_2500_D48K,beta-lactamase_2500_48,TEM-1,beta-lactamase_2500,P62593,0.220697,NO,48,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.101,-3.448,2.347,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.361275,0.0027273,0.220697 kka2_1:4_L170K,kka2_1:4_170,Kka2,kka2_1:4,P00552,0.220744,NO,170,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.28,-3.796,2.516,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.168804,0.00730791,0.220744 beta-lactamase_156_I125P,beta-lactamase_156_125,TEM-1,beta-lactamase_156,P62593,0.220789,NO,125,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.441,-4.116,2.675,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.111618,0.00383964,0.220789 beta-lactamase_156_L137R,beta-lactamase_156_137,TEM-1,beta-lactamase_156,P62593,0.220797,NO,137,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.03,-4,2.97,,,H,A,0.55,-0.38,0.674,,42.31,HHP,-1.58933,0.111618,0.00278599,0.220797 kka2_1:2_D261W,kka2_1:2_261,Kka2,kka2_1:2,P00552,0.220848,NO,261,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.708,-5.576,4.868,,0.146,G,A,0.75,-0.33,,,,HAA,-0.759333,0.295029,0.0224846,0.220848 beta-lactamase_2500_I45N,beta-lactamase_2500_45,TEM-1,beta-lactamase_2500,P62593,0.220865,NO,45,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-2.421,-3.135,0.714,,,E,B,0.48,-0.3,3.793,,77.62,HHA,-2.30267,0.361275,0.00452842,0.220865 Pab1_L142R,Pab1_142,Pab1,Pab1,P04147,0.220907,NO,142,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.039,-3.75,2.711,,0.007,H,A,0.84,-0.65,,,,HHH,-1.487,0.175299,0.000335477,0.220907 beta-lactamase_2500_T158Y,beta-lactamase_2500_158,TEM-1,beta-lactamase_2500,P62593,0.22093,NO,158,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.116,-4.258,3.142,,0.036,,B,0.22,-0.85,1.344,,69.58,HPB,-1.269,0.361275,0.00341825,0.22093 kka2_1:1_G210F,kka2_1:1_210,Kka2,kka2_1:1,P00552,0.220975,NO,210,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.095,-4.324,3.229,,0.103,T,A,0.29,-0.62,14.483,14.483,50,OOB,-0.966667,0.520039,0.00598378,0.220975 kka2_1:2_G213E,kka2_1:2_213,Kka2,kka2_1:2,P00552,0.220975,NO,213,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.596,-3.693,3.097,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.295029,0.00187654,0.220975 beta-lactamase_39_G43N,beta-lactamase_39_43,TEM-1,beta-lactamase_39,P62593,0.221029,NO,43,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.62,-3.448,2.828,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.0495842,0.00120151,0.221029 beta-lactamase_39_D129F,beta-lactamase_39_129,TEM-1,beta-lactamase_39,P62593,0.221043,NO,129,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.816,-4.318,3.502,,,,B,0.75,-0.69,0.56,,34.97,PAP,-0.818,0.0495842,0.00109178,0.221043 E1_Ubiquitin_G75H,E1_Ubiquitin_75,Uba1,E1_Ubiquitin,P0CG63,0.221043,NO,75,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.999,-4.421,3.422,,0.552,T,A,0.75,0.9,4.369,,83.73,BOO,-1.1,0.18783,0.00153276,0.221043 E1_Ubiquitin_R42E,E1_Ubiquitin_42,Uba1,E1_Ubiquitin,P0CG63,0.221043,NO,42,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.302,-3.025,1.723,,0.244,E,B,,-0.54,,,,PBH,-1.24667,0.18783,0.00224033,0.221043 beta-lactamase_2500_A133H,beta-lactamase_2500_133,TEM-1,beta-lactamase_2500,P62593,0.221155,NO,133,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.186,-4.769,3.583,,,H,A,0.46,-0.86,2.649,,67.83,HHP,-0.988333,0.361275,0.00468022,0.221155 beta-lactamase_625_N130W,beta-lactamase_625_130,TEM-1,beta-lactamase_625,P62593,0.221177,NO,130,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-0.798,-5.547,4.749,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.213352,0.000683376,0.221177 beta-lactamase_2500_G281H,beta-lactamase_2500_281,TEM-1,beta-lactamase_2500,P62593,0.221179,NO,281,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.361275,0.0406482,0.221179 beta-lactamase_625_I280D,beta-lactamase_625_280,TEM-1,beta-lactamase_625,P62593,0.221191,NO,280,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.213352,0.0530888,0.221191 kka2_1:8_A224H,kka2_1:8_224,Kka2,kka2_1:8,P00552,0.221199,NO,224,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.977,-4.809,3.832,,,H,A,0.46,-1.26,0.357,,63.64,HHP,-1.41033,0.100394,0.00352047,0.221199 kka2_1:8_A224H,kka2_1:8_224,Kka2,kka2_1:8,P00552,0.221199,NO,224,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.977,-4.809,3.832,,,H,A,0.46,-1.26,0.357,,63.64,HHP,-1.41033,0.100394,0.00352047,0.221199 kka2_1:8_N195P,kka2_1:8_195,Kka2,kka2_1:8,P00552,0.221199,NO,195,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-0.836,-3.906,3.07,,0.037,G,A,0.43,-1.36,1.108,,48.11,OPH,-1.26567,0.100394,0.00276134,0.221199 kka2_1:8_N195P,kka2_1:8_195,Kka2,kka2_1:8,P00552,0.221199,NO,195,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-0.836,-3.906,3.07,,0.037,G,A,0.43,-1.36,1.108,,48.11,OPH,-1.26567,0.100394,0.00276134,0.221199 beta-lactamase_156_D33P,beta-lactamase_156_33,TEM-1,beta-lactamase_156,P62593,0.221214,NO,33,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.321,-3.968,1.647,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.111618,0.00435556,0.221214 beta-lactamase_2500_G142M,beta-lactamase_2500_142,TEM-1,beta-lactamase_2500,P62593,0.221297,NO,142,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.707,-4.893,4.186,,0.034,,p,0.29,-0.64,1.883,,64.69,OOO,-0.834,0.361275,0.00060149,0.221297 beta-lactamase_625_P181E,beta-lactamase_625_181,TEM-1,beta-lactamase_625,P62593,0.221311,NO,181,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.813,-3.466,2.653,,,H,A,0.52,-1.14,1.797,,61.54,HOH,-1.795,0.213352,0.000703122,0.221311 kka2_1:8_L260K,kka2_1:8_260,Kka2,kka2_1:8,P00552,0.221375,NO,260,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.741,-3.71,2.969,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.100394,0.0233782,0.221375 kka2_1:8_L260K,kka2_1:8_260,Kka2,kka2_1:8,P00552,0.221375,NO,260,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.741,-3.71,2.969,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.100394,0.0233782,0.221375 kka2_1:1_Q26C,kka2_1:1_26,Kka2,kka2_1:1,P00552,0.221414,NO,26,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.18,-5.205,3.025,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.520039,0.00708962,0.221414 beta-lactamase_625_T126F,beta-lactamase_625_126,TEM-1,beta-lactamase_625,P62593,0.221416,NO,126,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.122,-4.199,3.077,,0.05,H,A,0.22,-0.05,0.817,,44.41,HPH,-1.60467,0.213352,0.00244552,0.221416 kka2_1:2_A215W,kka2_1:2_215,Kka2,kka2_1:2,P00552,0.221465,NO,215,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.968,-5.417,4.449,,0.039,E,B,0.46,-0.59,2.137,,50.38,HHA,-1.00467,0.295029,0.00529129,0.221465 beta-lactamase_2500_V117G,beta-lactamase_2500_117,TEM-1,beta-lactamase_2500,P62593,0.221521,NO,117,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.53,-3.828,2.298,,,H,A,0.44,-0.34,1.23,,65.03,PHB,-1.741,0.361275,0.00467906,0.221521 beta-lactamase_2500_F64T,beta-lactamase_2500_64,TEM-1,beta-lactamase_2500,P62593,0.221551,NO,64,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-0.841,-3.646,2.805,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.361275,0.000947691,0.221551 WW_domain_P202Q,WW_domain_202,Yap65,WW_domain,P46937,0.221557,NO,202,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.4,-3.776,2.376,5.64207,,,,,,17.28,17.28,78.57,AOB,-1.436,0.153962,0.00212903,0.221557 beta-lactamase_L167W,beta-lactamase_167,TEM-1,beta-lactamase,P62593,0.221564,NO,167,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.138,-5.22,4.082,5.13111,0.015,G,A,0.08,-0.63,0.4,,64.69,AHP,-1.30767,0.221079,0.00303566,0.221564 hsp90_A587L,hsp90_587,hsp90,hsp90,P02829,0.221723,NO,587,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.456,-2.511,0,4.91216,0.049,H,A,0.55,-0.02,,,,PHP,-2.757,0.368192,0.000222939,0.221723 beta-lactamase_39_L146D,beta-lactamase_39_146,TEM-1,beta-lactamase_39,P62593,0.221769,NO,146,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.462,-4.108,2.646,,0.007,H,A,0.55,-0.56,1.953,,64.69,AHP,-1.656,0.0495842,0.00474542,0.221769 beta-lactamase_39_I280G,beta-lactamase_39_280,TEM-1,beta-lactamase_39,P62593,0.221941,NO,280,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.0495842,0.0530888,0.221941 beta-lactamase_2500_L146K,beta-lactamase_2500_146,TEM-1,beta-lactamase_2500,P62593,0.221943,NO,146,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.462,-3.867,2.405,,0.007,H,A,0.55,-0.56,1.578,,64.69,AHP,-1.656,0.361275,0.00474542,0.221943 beta-lactamase_625_C75F,beta-lactamase_625_75,TEM-1,beta-lactamase_625,P62593,0.221943,NO,75,C,F,CF,Special,Hydrophobic,5.07,3.32051,-1.74949,205,121,165,44,108.5,189.9,81.4,-1.245,-4.17,2.925,,,H,A,0.46,-0.87,2.141,,50,HOO,-1.24333,0.213352,0.0034616,0.221943 beta-lactamase_2500_I93W,beta-lactamase_2500_93,TEM-1,beta-lactamase_2500,P62593,0.221948,NO,93,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.401,-5.418,4.017,,0.128,E,B,0.48,0.44,19.374,19.374,67.83,BHB,-1.873,0.361275,0.00527066,0.221948 kka2_1:2_T187Y,kka2_1:2_187,Kka2,kka2_1:2,P00552,0.221964,NO,187,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.273,-4.308,3.035,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.295029,0.00693073,0.221964 beta-lactamase_2500_T69G,beta-lactamase_2500_69,TEM-1,beta-lactamase_2500,P62593,0.221995,NO,69,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-0.973,-3.289,2.316,,,G,A,0.22,-1.24,2.05,,93.01,PPH,-1.01833,0.361275,0.00127498,0.221995 kka2_1:4_L232D,kka2_1:4_232,Kka2,kka2_1:4,P00552,0.222035,NO,232,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.514,-4.122,2.608,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.168804,0.00800103,0.222035 kka2_1:2_L107E,kka2_1:2_107,Kka2,kka2_1:2,P00552,0.222063,NO,107,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.238,-3.847,2.609,,0.197,,B,1.59,-1.1,2.68,,71.59,BHH,-2.143,0.295029,0.00561937,0.222063 kka2_1:8_R38W,kka2_1:8_38,Kka2,kka2_1:8,P00552,0.222078,NO,38,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.207,-5.334,4.127,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.100394,0.00372499,0.222078 kka2_1:8_R38W,kka2_1:8_38,Kka2,kka2_1:8,P00552,0.222078,NO,38,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.207,-5.334,4.127,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.100394,0.00372499,0.222078 kka2_1:2_L107W,kka2_1:2_107,Kka2,kka2_1:2,P00552,0.22216,NO,107,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.238,-5.321,4.083,,0.197,,B,1.59,-1.1,2.68,,71.59,BHH,-2.143,0.295029,0.00561937,0.22216 kka2_1:1_L193S,kka2_1:1_193,Kka2,kka2_1:1,P00552,0.222174,NO,193,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.983,-3.624,2.641,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.520039,0.00480179,0.222174 kka2_1:1_F133Y,kka2_1:1_133,Kka2,kka2_1:1,P00552,0.222181,NO,133,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-0.871,-2.422,1.551,,0.178,.,B,0.58,0.43,1.999,,42.42,OHA,-0.871667,0.520039,0.00182168,0.222181 beta-lactamase_2500_I93K,beta-lactamase_2500_93,TEM-1,beta-lactamase_2500,P62593,0.22221,NO,93,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.401,-3.873,2.472,,0.128,E,B,0.48,0.44,19.374,19.374,67.83,BHB,-1.873,0.361275,0.00527066,0.22221 beta-lactamase_156_Y262H,beta-lactamase_156_262,TEM-1,beta-lactamase_156,P62593,0.222236,NO,262,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.111618,0.00853516,0.222236 kka2_1:1_R173T,kka2_1:1_173,Kka2,kka2_1:1,P00552,0.222261,NO,173,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.407,-3.026,0.619,,0.308,H,A,0.16,-0.13,14.756,14.756,65.53,HBH,-1.70533,0.520039,0.00784999,0.222261 kka2_1:1_Y218W,kka2_1:1_218,Kka2,kka2_1:1,P00552,0.222287,NO,218,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-1.438,-3.229,1.791,,0.122,H,A,1.25,-0.69,3.059,,56.06,BHP,-1.17533,0.520039,0.0126098,0.222287 hsp90_W585A,hsp90_585,hsp90,hsp90,P02829,0.222357,NO,585,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-4.251,-2.456,0,5.31455,0.508,,B,1.22,0.43,,,,OHP,-3.17533,0.368192,0.000222939,0.222357 kka2_1:4_F171T,kka2_1:4_171,Kka2,kka2_1:4,P00552,0.222438,NO,171,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.326,-3.738,2.412,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.168804,0.00821426,0.222438 kka2_1:1_D261I,kka2_1:1_261,Kka2,kka2_1:1,P00552,0.222446,NO,261,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.708,-4.039,3.331,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.520039,0.0224846,0.222446 kka2_1:4_M148P,kka2_1:4_148,Kka2,kka2_1:4,P00552,0.222455,NO,148,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.847,-4.116,2.269,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.168804,0.00982664,0.222455 beta-lactamase_156_K232I,beta-lactamase_156_232,TEM-1,beta-lactamase_156,P62593,0.222468,NO,232,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.012,-4.053,3.041,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.111618,0.00313441,0.222468 kka2_1:1_D183I,kka2_1:1_183,Kka2,kka2_1:1,P00552,0.222523,NO,183,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.204,-3.991,2.787,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.520039,0.00426304,0.222523 beta-lactamase_625_D155G,beta-lactamase_625_155,TEM-1,beta-lactamase_625,P62593,0.2226,NO,155,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.889,-3.177,2.288,,0.049,,B,0.75,-0.9,4.922,,64.69,OAB,-1.62267,0.213352,0.00135315,0.2226 kka2_1:2_F263P,kka2_1:2_263,Kka2,kka2_1:2,P00552,0.222604,NO,263,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-0.911,-4.356,3.445,,0.006,G,A,1.62,-0.12,5.275,,45.83,AHH,-0.92,0.295029,0.0172454,0.222604 kka2_1:2_I228C,kka2_1:2_228,Kka2,kka2_1:2,P00552,0.222609,NO,228,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.142,-4.738,3.596,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.295029,0.00458834,0.222609 beta-lactamase_2500_L160K,beta-lactamase_2500_160,TEM-1,beta-lactamase_2500,P62593,0.222644,NO,160,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.977,-3.757,2.78,,0.022,,B,0.55,-0.6,0.895,,44.41,BHA,-0.936,0.361275,0.00193775,0.222644 kka2_1:1_G205N,kka2_1:1_205,Kka2,kka2_1:1,P00552,0.222666,NO,205,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.596,-3.476,2.88,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.520039,0.00221855,0.222666 kka2_1:2_L260F,kka2_1:2_260,Kka2,kka2_1:2,P00552,0.222723,NO,260,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.741,-3.645,2.904,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.295029,0.0233782,0.222723 kka2_1:1_R239P,kka2_1:1_239,Kka2,kka2_1:1,P00552,0.222863,NO,239,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.949,-1.624,-1.325,,0.15,H,A,1.2,-0.31,0.477,,71.59,ABH,-2.23,0.520039,0.00835326,0.222863 beta-lactamase_2500_V117S,beta-lactamase_2500_117,TEM-1,beta-lactamase_2500,P62593,0.222883,NO,117,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.53,-3.729,2.199,,,H,A,0.44,-0.34,1.23,,65.03,PHB,-1.741,0.361275,0.00467906,0.222883 beta-lactamase_625_S68H,beta-lactamase_625_68,TEM-1,beta-lactamase_625,P62593,0.222965,NO,68,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-0.913,-4.418,3.505,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.213352,0.000800065,0.222965 beta-lactamase_625_D129G,beta-lactamase_625_129,TEM-1,beta-lactamase_625,P62593,0.222991,NO,129,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.816,-3.182,2.366,,,,B,0.75,-0.69,0.171,,34.97,PAP,-0.818,0.213352,0.00109178,0.222991 kka2_1:4_L241W,kka2_1:4_241,Kka2,kka2_1:4,P00552,0.223027,NO,241,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.158,-4.909,3.751,,0.08,H,A,0.55,-0.82,1.598,,63.26,HHH,-1.58533,0.168804,0.0117299,0.223027 PSD95pdz3_L323R,PSD95pdz3_323,PSD95pdz3,PSD95pdz3,P31016,0.223031,NO,323,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.347,-3.615,2.268,5.12397,,,,,13.8825,,,,OHO,-1.121,0.0758425,0.00104644,0.223031 Pab1_G169E,Pab1_169,Pab1,Pab1,P04147,0.223053,NO,169,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.809,-3.482,2.673,,,E,b,0.35,0.03,,,,HOH,-1.11567,0.175299,0.000302434,0.223053 kka2_1:2_A222K,kka2_1:2_222,Kka2,kka2_1:2,P00552,0.223063,NO,222,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.725,-3.485,2.76,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.295029,0.00207657,0.223063 gb1_A249F,gb1_249,gb1,gb1,P06654,0.22307,NO,249,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.739,-3.98,2.241,,,,,,,0.252,,44.87,AHH,-1.67367,0.177985,0.00333585,0.22307 gb1_A252Y,gb1_252,gb1,gb1,P06654,0.22307,NO,252,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.175,-3.898,2.723,,,,,,,,,,PHA,-1.55967,0.177985,0.00125598,0.22307 gb1_G267L,gb1_267,gb1,gb1,P06654,0.22307,NO,267,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.676,-2.111,0.435,,,,,,,1.361,,12.72,AOA,-1.61833,0.177985,0.00264655,0.22307 gb1_N261Q,gb1_261,gb1,gb1,P06654,0.22307,NO,261,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-1.863,-3.632,1.769,,,,,,,1.191,,44.87,HPA,-2.16033,0.177985,0.0061875,0.22307 gb1_V265P,gb1_265,gb1,gb1,P06654,0.22307,NO,265,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.843,-3.684,1.841,,,,,,,0.402,,11.83,OHA,-1.64567,0.177985,0.00360613,0.22307 gb1_W269Y,gb1_269,gb1,gb1,P06654,0.22307,NO,269,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-1.198,-3.039,1.841,,,,,,,,,,AHP,-2.08867,0.177985,0.00270706,0.22307 gb1_Y259P,gb1_259,gb1,gb1,P06654,0.22307,NO,259,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-1.78,-4.105,2.325,,,,,,,0.131,,11.83,PHH,-1.787,0.177985,0.00464313,0.22307 kka2_1:2_G189A,kka2_1:2_189,Kka2,kka2_1:2,P00552,0.223091,NO,189,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.596,-2.881,2.285,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.295029,0.00253688,0.223091 beta-lactamase_156_I277P,beta-lactamase_156_277,TEM-1,beta-lactamase_156,P62593,0.223105,NO,277,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.111618,0.0169305,0.223105 kka2_1:2_L107A,kka2_1:2_107,Kka2,kka2_1:2,P00552,0.223115,NO,107,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.238,-3.204,1.966,,0.197,,B,1.59,-1.1,2.68,,71.59,BHH,-2.143,0.295029,0.00561937,0.223115 beta-lactamase_625_C121N,beta-lactamase_625_121,TEM-1,beta-lactamase_625,P62593,0.223117,NO,121,C,N,CN,Special,Polar,5.07,5.47157,0.401575,139,121,132,11,108.5,114.1,5.6,-0.953,-4.045,3.092,,,H,A,0.46,-0.81,1.143,,63.29,HOP,-1.46767,0.213352,0.000744322,0.223117 beta-lactamase_625_A230R,beta-lactamase_625_230,TEM-1,beta-lactamase_625,P62593,0.223134,NO,230,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.154,-3.858,2.704,,0.01,E,B,0.46,-1.17,0.777,,50,HHA,-1.079,0.213352,0.00516841,0.223134 kka2_1:2_P109F,kka2_1:2_109,Kka2,kka2_1:2,P00552,0.22317,NO,109,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.412,-4.386,2.974,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.295029,0.0070929,0.22317 beta-lactamase_2500_G281Q,beta-lactamase_2500_281,TEM-1,beta-lactamase_2500,P62593,0.223171,NO,281,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.361275,0.0406482,0.223171 beta-lactamase_V257N,beta-lactamase_257,TEM-1,beta-lactamase,P62593,0.22327,NO,257,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.533,-4.141,2.608,5.31999,,E,B,0.96,-0.7,1.463,,58.74,HHH,-1.70967,0.221079,0.00756629,0.22327 kka2_1:4_P194E,kka2_1:4_194,Kka2,kka2_1:4,P00552,0.223273,NO,194,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.846,-3.407,2.561,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.168804,0.00314194,0.223273 kka2_1:1_G189M,kka2_1:1_189,Kka2,kka2_1:1,P00552,0.223281,NO,189,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.596,-4.958,4.362,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.520039,0.00253688,0.223281 beta-lactamase_625_G85P,beta-lactamase_625_85,TEM-1,beta-lactamase_625,P62593,0.223283,NO,85,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.011,-3.891,2.88,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.213352,0.00252173,0.223283 kka2_1:8_F263Q,kka2_1:8_263,Kka2,kka2_1:8,P00552,0.223306,NO,263,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-0.911,-4.376,3.465,,0.006,G,A,1.62,-0.12,0.928,,45.83,AHH,-0.92,0.100394,0.0172454,0.223306 kka2_1:8_F263Q,kka2_1:8_263,Kka2,kka2_1:8,P00552,0.223306,NO,263,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-0.911,-4.376,3.465,,0.006,G,A,1.62,-0.12,0.928,,45.83,AHH,-0.92,0.100394,0.0172454,0.223306 kka2_1:1_T72W,kka2_1:1_72,Kka2,kka2_1:1,P00552,0.223314,NO,72,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.38,-5.516,3.136,,0.784,H,A,0.22,0.29,10.43,10.43,65.53,HPP,-2.238,0.520039,0.00750756,0.223314 beta-lactamase_39_R59P,beta-lactamase_39_59,TEM-1,beta-lactamase_39,P62593,0.223341,NO,59,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.345,-3.961,2.616,,0.329,S,L,1.2,-0.09,1.806,,73.08,HBO,-2.24267,0.0495842,0.00318082,0.223341 kka2_1:1_F37R,kka2_1:1_37,Kka2,kka2_1:1,P00552,0.223363,NO,37,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.427,-4.151,2.724,,0.219,E,B,0.58,-0.25,18.64,18.64,64.39,HHB,-1.17733,0.520039,0.00586193,0.223363 beta-lactamase_2500_P181L,beta-lactamase_2500_181,TEM-1,beta-lactamase_2500,P62593,0.223376,NO,181,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.813,-3.546,2.733,,,H,A,0.52,-1.14,1.946,,61.54,HOH,-1.795,0.361275,0.000703122,0.223376 kka2_1:2_C77W,kka2_1:2_77,Kka2,kka2_1:2,P00552,0.223404,NO,77,C,W,CW,Special,Hydrophobic,5.07,5.89,0.82,215,121,204,83,108.5,227.8,119.3,-1.477,-5.341,3.864,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.295029,0.00441216,0.223404 kka2_1:1_L174E,kka2_1:1_174,Kka2,kka2_1:1,P00552,0.223437,NO,174,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.952,-3.9,2.948,,,H,A,0.55,-0.31,13.276,13.276,51.89,BHB,-2.08533,0.520039,0.00438501,0.223437 kka2_1:1_T28E,kka2_1:1_28,Kka2,kka2_1:1,P00552,0.223471,NO,28,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.883,-2.677,0.794,,0.353,S,B,0.22,2.02,1.12,,63.64,PPH,-1.74467,0.520039,0.00743084,0.223471 kka2_1:1_F37A,kka2_1:1_37,Kka2,kka2_1:1,P00552,0.223478,NO,37,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.427,-2.571,1.144,,0.219,E,B,0.58,-0.25,18.64,18.64,64.39,HHB,-1.17733,0.520039,0.00586193,0.223478 kka2_1:4_G99Y,kka2_1:4_99,Kka2,kka2_1:4,P00552,0.223546,NO,99,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.596,-4.416,3.82,,0.368,S,g,0.29,-0.87,,,,OOP,-1.63067,0.168804,0.00186055,0.223546 kka2_1:1_L232S,kka2_1:1_232,Kka2,kka2_1:1,P00552,0.223547,NO,232,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.514,-3.04,1.526,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.520039,0.00800103,0.223547 beta-lactamase_V78G,beta-lactamase_78,TEM-1,beta-lactamase,P62593,0.223548,NO,78,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.459,-2.817,1.358,4.79197,,H,A,0.96,-0.47,1.132,,63.64,HHH,-1.17833,0.221079,0.00492501,0.223548 beta-lactamase_2500_L218H,beta-lactamase_2500_218,TEM-1,beta-lactamase_2500,P62593,0.223551,NO,218,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.391,-4.744,3.353,,,I,b,0.55,-0.53,9.151,9.151,74.48,OHH,-1.58867,0.361275,0.00618274,0.223551 kka2_1:1_G210H,kka2_1:1_210,Kka2,kka2_1:1,P00552,0.223574,NO,210,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.095,-4.794,3.699,,0.103,T,A,0.29,-0.62,14.483,14.483,50,OOB,-0.966667,0.520039,0.00598378,0.223574 kka2_1:2_G233P,kka2_1:2_233,Kka2,kka2_1:2,P00552,0.223582,NO,233,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.748,-3.907,3.159,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.295029,0.00232366,0.223582 kka2_1:2_D208V,kka2_1:2_208,Kka2,kka2_1:2,P00552,0.223604,NO,208,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.708,-3.782,3.074,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.295029,0.00212588,0.223604 beta-lactamase_625_K232S,beta-lactamase_625_232,TEM-1,beta-lactamase_625,P62593,0.223621,NO,232,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.012,-3.258,2.246,,,E,B,2.34,-1.1,1.992,,65.03,ABP,-1.238,0.213352,0.00313441,0.223621 kka2_1:8_A117F,kka2_1:8_117,Kka2,kka2_1:8,P00552,0.223656,NO,117,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.828,-4.094,3.266,,,H,A,1.04,-0.78,0.755,,45.83,HHA,-1.79333,0.100394,0.00282984,0.223656 kka2_1:8_A117F,kka2_1:8_117,Kka2,kka2_1:8,P00552,0.223656,NO,117,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.828,-4.094,3.266,,,H,A,1.04,-0.78,0.755,,45.83,HHA,-1.79333,0.100394,0.00282984,0.223656 beta-lactamase_2500_D174H,beta-lactamase_2500_174,TEM-1,beta-lactamase_2500,P62593,0.223663,NO,174,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.738,-4.455,3.717,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.361275,0.00125633,0.223663 kka2_1:2_V113E,kka2_1:2_113,Kka2,kka2_1:2,P00552,0.223676,NO,113,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.233,-3.887,2.654,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.295029,0.00650191,0.223676 beta-lactamase_625_Y262W,beta-lactamase_625_262,TEM-1,beta-lactamase_625,P62593,0.223687,NO,262,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.213352,0.00853516,0.223687 kka2_1:1_V153P,kka2_1:1_153,Kka2,kka2_1:1,P00552,0.223724,NO,153,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.092,-4.027,2.935,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.520039,0.00501119,0.223724 beta-lactamase_P65W,beta-lactamase_65,TEM-1,beta-lactamase,P62593,0.223735,NO,65,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.894,-5.47,4.576,5.59094,0.098,E,B,0.23,-0.62,0.623,,40.56,HOH,-1.03233,0.221079,0.00152776,0.223735 kka2_1:2_D127F,kka2_1:2_127,Kka2,kka2_1:2,P00552,0.223853,NO,127,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.364,-4.509,3.145,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.295029,0.00660501,0.223853 beta-lactamase_2500_E279P,beta-lactamase_2500_279,TEM-1,beta-lactamase_2500,P62593,0.223893,NO,279,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.361275,0.0192826,0.223893 kka2_1:1_R226Q,kka2_1:1_226,Kka2,kka2_1:1,P00552,0.223902,NO,226,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.392,-2.994,1.602,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.520039,0.0108032,0.223902 kka2_1:4_D261W,kka2_1:4_261,Kka2,kka2_1:4,P00552,0.22395,NO,261,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.708,-5.576,4.868,,0.146,G,A,0.75,-0.33,,,,HAA,-0.759333,0.168804,0.0224846,0.22395 kka2_1:2_V186N,kka2_1:2_186,Kka2,kka2_1:2,P00552,0.223979,NO,186,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.011,-4.235,3.224,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.295029,0.00409703,0.223979 kka2_1:1_P179N,kka2_1:1_179,Kka2,kka2_1:1,P00552,0.223987,NO,179,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.974,-3.967,2.993,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.520039,0.00298346,0.223987 kka2_1:4_Y22Q,kka2_1:4_22,Kka2,kka2_1:4,P00552,0.224058,NO,22,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-1.583,-4.105,2.522,,0.122,.,B,0.21,-0.8,1.838,,65.53,OHA,-1.80333,0.168804,0.00598977,0.224058 kka2_1:2_A34D,kka2_1:2_34,Kka2,kka2_1:2,P00552,0.224076,NO,34,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.928,-3.625,2.697,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.295029,0.00343484,0.224076 kka2_1:4_F203K,kka2_1:4_203,Kka2,kka2_1:4,P00552,0.224113,NO,203,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-0.911,-3.934,3.023,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.168804,0.00318738,0.224113 beta-lactamase_39_I277K,beta-lactamase_39_277,TEM-1,beta-lactamase_39,P62593,0.224127,NO,277,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.0495842,0.0169305,0.224127 kka2_1:1_E169N,kka2_1:1_169,Kka2,kka2_1:1,P00552,0.224192,NO,169,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.996,-3.126,1.13,,0.422,H,A,1.04,0.3,7.546,7.546,65.53,HAH,-1.755,0.520039,0.00730086,0.224192 beta-lactamase_625_S233M,beta-lactamase_625_233,TEM-1,beta-lactamase_625,P62593,0.224195,NO,233,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.886,-4.626,2.74,,0.016,E,B,0.27,-1.01,1.773,,77.62,BPO,-1.17267,0.213352,0.00311415,0.224195 beta-lactamase_2500_A230R,beta-lactamase_2500_230,TEM-1,beta-lactamase_2500,P62593,0.224219,NO,230,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.154,-3.858,2.704,,0.01,E,B,0.46,-1.17,1.171,,50,HHA,-1.079,0.361275,0.00516841,0.224219 beta-lactamase_2500_C75D,beta-lactamase_2500_75,TEM-1,beta-lactamase_2500,P62593,0.224278,NO,75,C,D,CD,Special,negativeCharge,5.07,5.0516,-0.0184,154,121,133,12,108.5,111.1,2.6,-1.245,-3.832,2.587,,,H,A,0.46,-0.87,0.844,,50,HOO,-1.24333,0.361275,0.0034616,0.224278 beta-lactamase_2500_V106P,beta-lactamase_2500_106,TEM-1,beta-lactamase_2500,P62593,0.224383,NO,106,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.218,-4.094,2.876,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.361275,0.00304168,0.224383 beta-lactamase_156_I245E,beta-lactamase_156_245,TEM-1,beta-lactamase_156,P62593,0.224421,NO,245,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.111618,0.00391032,0.224421 kka2_1:2_I115C,kka2_1:2_115,Kka2,kka2_1:2,P00552,0.224474,NO,115,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.606,-4.846,3.24,,0.105,H,A,0.48,-1.18,0.878,,65.53,PHH,-2.205,0.295029,0.00836567,0.224474 beta-lactamase_625_A230E,beta-lactamase_625_230,TEM-1,beta-lactamase_625,P62593,0.224546,NO,230,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.154,-3.566,2.412,,0.01,E,B,0.46,-1.17,0.777,,50,HHA,-1.079,0.213352,0.00516841,0.224546 beta-lactamase_2500_S51P,beta-lactamase_2500_51,TEM-1,beta-lactamase_2500,P62593,0.224552,NO,51,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.526,-3.858,2.332,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.361275,0.00504821,0.224552 E1_Ubiquitin_G75T,E1_Ubiquitin_75,Uba1,E1_Ubiquitin,P0CG63,0.22458,NO,75,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.999,-3.457,2.458,,0.552,T,A,0.75,0.9,4.369,,83.73,BOO,-1.1,0.18783,0.00153276,0.22458 kka2_1:4_T187Y,kka2_1:4_187,Kka2,kka2_1:4,P00552,0.224586,NO,187,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.273,-4.308,3.035,,0.007,E,B,0.22,-0.85,2.73,,52.27,HPB,-1.06567,0.168804,0.00693073,0.224586 beta-lactamase_0_A123V,beta-lactamase_0_123,TEM-1,beta-lactamase_0,P62593,0.224592,NO,123,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.834,-2.392,1.558,,0.039,H,A,0.46,-0.72,1.308,,41.26,PHH,-1.47367,0.0500837,0.0010157,0.224592 beta-lactamase_39_D177V,beta-lactamase_39_177,TEM-1,beta-lactamase_39,P62593,0.224639,NO,177,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.967,-3.739,2.772,,0.006,T,L,0.75,-1.02,3.536,,64.69,BAP,-0.873667,0.0495842,0.000864022,0.224639 beta-lactamase_625_L120P,beta-lactamase_625_120,TEM-1,beta-lactamase_625,P62593,0.224641,NO,120,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.044,-4.17,3.126,,,H,A,0.55,-1.13,7.813,,64.69,AHO,-1.13633,0.213352,0.00143563,0.224641 kka2_1:4_R211A,kka2_1:4_211,Kka2,kka2_1:4,P00552,0.224674,NO,211,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-0.899,-3.167,2.268,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.168804,0.00204888,0.224674 kka2_1:4_V185Y,kka2_1:4_185,Kka2,kka2_1:4,P00552,0.224718,NO,185,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.045,-4.096,3.051,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.168804,0.00367031,0.224718 kka2_1:1_M148S,kka2_1:1_148,Kka2,kka2_1:1,P00552,0.224755,NO,148,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.847,-3.618,1.771,,0.268,H,A,1.59,0.71,4.618,,64.39,BHA,-1.65467,0.520039,0.00982664,0.224755 kka2_1:1_M178S,kka2_1:1_178,Kka2,kka2_1:1,P00552,0.224772,NO,178,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-3.206,-2.817,-0.389,,0.554,.,b,0.55,0.68,3.152,,71.59,BHO,-2.154,0.520039,0.00717253,0.224772 kka2_1:1_L19G,kka2_1:1_19,Kka2,kka2_1:1,P00552,0.224811,NO,19,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.254,-3.863,2.609,,0.08,T,A,0.55,-0.26,17.165,17.165,65.53,BHH,-2.221,0.520039,0.00620703,0.224811 kka2_1:1_L19K,kka2_1:1_19,Kka2,kka2_1:1,P00552,0.224811,NO,19,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.254,-3.899,2.645,,0.08,T,A,0.55,-0.26,17.165,17.165,65.53,BHH,-2.221,0.520039,0.00620703,0.224811 kka2_1:1_E230W,kka2_1:1_230,Kka2,kka2_1:1,P00552,0.224815,NO,230,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.672,-5.201,2.529,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.520039,0.00920051,0.224815 beta-lactamase_625_I45W,beta-lactamase_625_45,TEM-1,beta-lactamase_625,P62593,0.224834,NO,45,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-2.421,-5.294,2.873,,,E,B,0.48,-0.3,3.642,,77.62,HHA,-2.30267,0.213352,0.00452842,0.224834 kka2_1:2_F240Y,kka2_1:2_240,Kka2,kka2_1:2,P00552,0.224846,NO,240,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-0.911,-3.189,2.278,,,H,A,0.58,-1.21,0.373,,50.38,BHH,-1.67267,0.295029,0.00552543,0.224846 kka2_1:1_G30Q,kka2_1:1_30,Kka2,kka2_1:1,P00552,0.224852,NO,30,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.596,-4.153,3.557,,0.54,S,g,0.29,3.76,,,,HOO,-1.51133,0.520039,0.00159208,0.224852 beta-lactamase_2500_T158I,beta-lactamase_2500_158,TEM-1,beta-lactamase_2500,P62593,0.22486,NO,158,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.116,-3.731,2.615,,0.036,,B,0.22,-0.85,1.344,,69.58,HPB,-1.269,0.361275,0.00341825,0.22486 kka2_1:1_I115G,kka2_1:1_115,Kka2,kka2_1:1,P00552,0.224883,NO,115,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.606,-3.814,2.208,,0.105,H,A,0.48,-1.18,0.878,,65.53,PHH,-2.205,0.520039,0.00836567,0.224883 kka2_1:4_D227F,kka2_1:4_227,Kka2,kka2_1:4,P00552,0.224885,NO,227,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.758,-4.199,2.441,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.168804,0.00745029,0.224885 kka2_1:4_V97Y,kka2_1:4_97,Kka2,kka2_1:4,P00552,0.2249,NO,97,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.453,-4.124,2.671,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.168804,0.00737869,0.2249 beta-lactamase_625_M184E,beta-lactamase_625_184,TEM-1,beta-lactamase_625,P62593,0.224916,NO,184,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.593,-3.708,2.115,,,H,A,0.55,-0.87,2.765,,62.94,HHH,-1.41,0.213352,0.00356019,0.224916 kka2_1:4_D208H,kka2_1:4_208,Kka2,kka2_1:4,P00552,0.22492,NO,208,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.708,-4.483,3.775,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.168804,0.00212588,0.22492 beta-lactamase_2500_R257N,beta-lactamase_2500_257,TEM-1,beta-lactamase_2500,P62593,0.224924,NO,257,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.361275,0.00756629,0.224924 kka2_1:2_H135K,kka2_1:2_135,Kka2,kka2_1:2,P00552,0.224949,NO,135,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-1.331,-3.419,2.088,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.295029,0.00532566,0.224949 beta-lactamase_625_M153P,beta-lactamase_625_153,TEM-1,beta-lactamase_625,P62593,0.225006,NO,153,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-3.193,-4.07,0.877,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.213352,0.00509109,0.225006 beta-lactamase_39_K232Q,beta-lactamase_39_232,TEM-1,beta-lactamase_39,P62593,0.225052,NO,232,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.012,-3.492,2.48,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.0495842,0.00313441,0.225052 beta-lactamase_2500_L136Q,beta-lactamase_2500_136,TEM-1,beta-lactamase_2500,P62593,0.225125,NO,136,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.232,-4.242,3.01,,,H,A,0.55,-0.34,1.36,,48.95,HHH,-1.088,0.361275,0.00442304,0.225125 beta-lactamase_2500_A246R,beta-lactamase_2500_246,TEM-1,beta-lactamase_2500,P62593,0.225193,NO,246,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.121,-4.154,2.033,,0.01,E,B,0.46,-1.01,0.753,,73.78,HHH,-1.55633,0.361275,0.00569458,0.225193 beta-lactamase_156_I277G,beta-lactamase_156_277,TEM-1,beta-lactamase_156,P62593,0.225258,NO,277,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.111618,0.0169305,0.225258 beta-lactamase_625_P181Y,beta-lactamase_625_181,TEM-1,beta-lactamase_625,P62593,0.225266,NO,181,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.813,-4.385,3.572,,,H,A,0.52,-1.14,1.797,,61.54,HOH,-1.795,0.213352,0.000703122,0.225266 beta-lactamase_39_A124F,beta-lactamase_39_124,TEM-1,beta-lactamase_39,P62593,0.225271,NO,124,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.181,-4.133,2.952,,,H,A,0.46,-0.9,1.367,,64.34,HHH,-1.152,0.0495842,0.00481399,0.225271 kka2_1:1_D227W,kka2_1:1_227,Kka2,kka2_1:1,P00552,0.225272,NO,227,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.758,-5.454,3.696,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.520039,0.00745029,0.225272 kka2_1:8_H162E,kka2_1:8_162,Kka2,kka2_1:8,P00552,0.225399,NO,162,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-2.319,-3.397,1.078,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.100394,0.00616145,0.225399 kka2_1:8_H162E,kka2_1:8_162,Kka2,kka2_1:8,P00552,0.225399,NO,162,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-2.319,-3.397,1.078,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.100394,0.00616145,0.225399 kka2_1:4_Y257E,kka2_1:4_257,Kka2,kka2_1:4,P00552,0.22543,NO,257,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-1.064,-3.82,2.756,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.168804,0.0148191,0.22543 beta-lactamase_V117K,beta-lactamase_117,TEM-1,beta-lactamase,P62593,0.225442,NO,117,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.53,-3.844,2.314,5.33594,,H,A,1.19,-0.34,1.182,,65.03,PHB,-1.741,0.221079,0.00467906,0.225442 kka2_1:1_A255Q,kka2_1:1_255,Kka2,kka2_1:1,P00552,0.225473,NO,255,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.715,-4.01,2.295,,0.466,H,A,0.46,-0.52,0.946,,65.53,HHH,-1.71267,0.520039,0.0126809,0.225473 beta-lactamase_T187R,beta-lactamase_187,TEM-1,beta-lactamase,P62593,0.22548,NO,187,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.401,-3.885,2.484,5.11453,0.007,H,A,0.3,-1.19,1.751,,67.48,PPH,-1.69633,0.221079,0.00491782,0.22548 beta-lactamase_625_N168F,beta-lactamase_625_168,TEM-1,beta-lactamase_625,P62593,0.225502,NO,168,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-1.029,-4.27,3.241,,0.113,G,A,0.61,-0.4,1.014,,44.41,HPA,-1.13233,0.213352,0.00288667,0.225502 beta-lactamase_2500_N274R,beta-lactamase_2500_274,TEM-1,beta-lactamase_2500,P62593,0.225532,NO,274,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.361275,0.0110418,0.225532 kka2_1:2_D190P,kka2_1:2_190,Kka2,kka2_1:2,P00552,0.225533,NO,190,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.708,-3.683,2.975,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.295029,0.00247989,0.225533 kka2_1:1_A41N,kka2_1:1_41,Kka2,kka2_1:1,P00552,0.225551,NO,41,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.879,-3.231,1.352,,0.184,.,B,0.46,-0.96,18.207,18.207,64.39,PHP,-2.477,0.520039,0.00543332,0.225551 beta-lactamase_156_D155H,beta-lactamase_156_155,TEM-1,beta-lactamase_156,P62593,0.225553,NO,155,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.889,-4.424,3.535,,0.049,,B,0.75,-0.9,0.315,,64.69,OAB,-1.62267,0.111618,0.00135315,0.225553 kka2_1:2_W69N,kka2_1:2_69,Kka2,kka2_1:2,P00552,0.225568,NO,69,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-0.859,-4.344,3.485,,0.164,H,A,0.47,0.15,5.074,,38.64,PHH,-1.49967,0.295029,0.0012874,0.225568 beta-lactamase_625_G240V,beta-lactamase_625_240,TEM-1,beta-lactamase_625,P62593,0.225579,NO,240,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.213352,0.00591201,0.225579 kka2_1:1_F203G,kka2_1:1_203,Kka2,kka2_1:1,P00552,0.225595,NO,203,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-0.911,-3.675,2.764,,0.26,E,B,0.58,-0.92,7.323,,63.64,BHP,-1.34167,0.520039,0.00318738,0.225595 Pab1_G169D,Pab1_169,Pab1,Pab1,P04147,0.225606,NO,169,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.809,-3.286,2.477,,,E,b,0.35,0.03,,,,HOH,-1.11567,0.175299,0.000302434,0.225606 beta-lactamase_39_M209R,beta-lactamase_39_209,TEM-1,beta-lactamase_39,P62593,0.225673,NO,209,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.442,-3.939,2.497,,,H,A,0.55,-0.97,1.167,,64.69,HHA,-1.52633,0.0495842,0.00625021,0.225673 beta-lactamase_F64T,beta-lactamase_64,TEM-1,beta-lactamase,P62593,0.225678,NO,64,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-0.841,-3.646,2.805,5.70769,0.006,E,B,1.33,-0.95,,,,BHO,-0.892667,0.221079,0.000947691,0.225678 kka2_1:1_L107A,kka2_1:1_107,Kka2,kka2_1:1,P00552,0.225693,NO,107,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.238,-3.204,1.966,,0.197,.,B,0.55,-1.1,3.542,,71.59,BHH,-2.143,0.520039,0.00561937,0.225693 kka2_1:1_W236F,kka2_1:1_236,Kka2,kka2_1:1,P00552,0.225705,NO,236,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-1.363,-2.652,1.289,,0.303,H,A,1.51,-0.76,12.263,12.263,48.48,AHH,-1.81267,0.520039,0.0088796,0.225705 kka2_1:1_L259E,kka2_1:1_259,Kka2,kka2_1:1,P00552,0.22574,NO,259,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.088,-3.851,2.763,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.520039,0.0206964,0.22574 beta-lactamase_39_A185Y,beta-lactamase_39_185,TEM-1,beta-lactamase_39,P62593,0.225743,NO,185,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.406,-4.227,2.821,,,H,A,0.46,-1.02,2.68,,65.03,HHP,-1.84033,0.0495842,0.00467449,0.225743 kka2_1:8_H188G,kka2_1:8_188,Kka2,kka2_1:8,P00552,0.225747,NO,188,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-0.913,-3.41,2.497,,0.006,,A,0.87,-1.02,1.241,,47.73,PBO,-0.927333,0.100394,0.00273139,0.225747 kka2_1:8_H188G,kka2_1:8_188,Kka2,kka2_1:8,P00552,0.225747,NO,188,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-0.913,-3.41,2.497,,0.006,,A,0.87,-1.02,1.241,,47.73,PBO,-0.927333,0.100394,0.00273139,0.225747 Ubiquitin_G75L,Ubiquitin_75,Uba1,Ubiquitin,P0CG48,0.225806,NO,75,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.613,-3.567,1.954,5.44099,0.552,T,A,0.73,0.9,4.017,,34.31,BOO,-1.66767,0.205827,0.000712673,0.225806 Ubiquitin_G75M,Ubiquitin_75,Uba1,Ubiquitin,P0CG48,0.225806,NO,75,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.613,-4.794,3.181,5.44099,0.552,T,A,0.73,0.9,4.017,,34.31,BOO,-1.66767,0.205827,0.000712673,0.225806 Ubiquitin_H68D,Ubiquitin_68,Uba1,Ubiquitin,P0CG48,0.225806,NO,68,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-1.869,-2.666,0.797,4.81902,0.194,E,B,0.72,-1.02,21.325,21.325,65.11,HBH,-1.583,0.205827,0.000925438,0.225806 Ubiquitin_K48I,Ubiquitin_48,Uba1,Ubiquitin,P0CG48,0.225806,NO,48,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.436,-2.886,1.45,5.03072,0.132,E,B,2.92,-0.28,1.539,,53.87,OBP,-1.6,0.205827,0.000394633,0.225806 Ubiquitin_L69D,Ubiquitin_69,Uba1,Ubiquitin,P0CG48,0.225806,NO,69,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.445,-3.927,2.482,4.75624,0.051,E,B,2.89,-0.94,7.106,,34.31,BHH,-1.72933,0.205827,0.000919136,0.225806 Ubiquitin_R72E,Ubiquitin_72,Uba1,Ubiquitin,P0CG48,0.225806,NO,72,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.034,-3.542,1.508,5.19484,0.077,,B,1.41,-0.1,9.638,9.638,42.77,HBH,-1.82733,0.205827,0.000768249,0.225806 Ubiquitin_T9F,Ubiquitin_9,Uba1,Ubiquitin,P0CG48,0.225806,NO,9,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.409,-4.156,2.747,5.24336,0.777,T,A,2.12,-0.12,2.705,,29.93,HPO,-1.50933,0.205827,0.000630716,0.225806 Ubiquitin_V17D,Ubiquitin_17,Uba1,Ubiquitin,P0CG48,0.225806,NO,17,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.314,-3.923,2.609,5.26282,0.017,,B,2.78,-0.77,3.239,,71.82,AHA,-1.51833,0.205827,0.000659638,0.225806 kka2_1:1_G99W,kka2_1:1_99,Kka2,kka2_1:1,P00552,0.225808,NO,99,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.596,-5.126,4.53,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.520039,0.00186055,0.225808 beta-lactamase_2500_G236R,beta-lactamase_2500_236,TEM-1,beta-lactamase_2500,P62593,0.225814,NO,236,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.784,-3.932,3.148,,0.241,,b,0.29,-0.59,2.14,,64.69,HOO,-1.025,0.361275,0.00162372,0.225814 beta-lactamase_625_G234E,beta-lactamase_625_234,TEM-1,beta-lactamase_625,P62593,0.22582,NO,234,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.62,-3.665,3.045,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.213352,0.000889577,0.22582 beta-lactamase_625_I277W,beta-lactamase_625_277,TEM-1,beta-lactamase_625,P62593,0.225821,NO,277,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.213352,0.0169305,0.225821 kka2_1:2_D156I,kka2_1:2_156,Kka2,kka2_1:2,P00552,0.225887,NO,156,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.696,-4.017,2.321,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.295029,0.00926998,0.225887 kka2_1:2_Y244I,kka2_1:2_244,Kka2,kka2_1:2,P00552,0.225887,NO,244,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-0.775,-3.589,2.814,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.295029,0.00453187,0.225887 kka2_1:1_A14Y,kka2_1:1_14,Kka2,kka2_1:1,P00552,0.225972,NO,14,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.837,-4.418,2.581,,0.728,G,A,0.46,0.7,1.17,,71.59,HHH,-1.82567,0.520039,0.00706614,0.225972 beta-lactamase_I275H,beta-lactamase_275,TEM-1,beta-lactamase,P62593,0.225977,NO,275,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.397,-3.183,1.786,5.3999,0.015,H,A,1,-0.52,0.836,,62.59,PHH,-1.541,0.221079,0.0141984,0.225977 kka2_1:2_T225Q,kka2_1:2_225,Kka2,kka2_1:2,P00552,0.226015,NO,225,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.393,-3.262,0.869,,0.036,H,A,0.22,-1.22,4.554,,63.64,HPB,-1.58733,0.295029,0.0113598,0.226015 beta-lactamase_625_I244N,beta-lactamase_625_244,TEM-1,beta-lactamase_625,P62593,0.226019,NO,244,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.555,-4.114,2.559,,,E,B,0.48,-0.84,2.061,,77.62,OHH,-1.385,0.213352,0.00605379,0.226019 beta-lactamase_625_D155F,beta-lactamase_625_155,TEM-1,beta-lactamase_625,P62593,0.226088,NO,155,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.889,-4.341,3.452,,0.049,,B,0.75,-0.9,4.922,,64.69,OAB,-1.62267,0.213352,0.00135315,0.226088 beta-lactamase_2500_A185I,beta-lactamase_2500_185,TEM-1,beta-lactamase_2500,P62593,0.226097,NO,185,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.406,-3.361,1.955,,,H,A,0.46,-1.02,2.999,,65.03,HHP,-1.84033,0.361275,0.00467449,0.226097 kka2_1:2_P179K,kka2_1:2_179,Kka2,kka2_1:2,P00552,0.2261,NO,179,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.974,-3.58,2.606,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.295029,0.00298346,0.2261 kka2_1:1_L107I,kka2_1:1_107,Kka2,kka2_1:1,P00552,0.22614,NO,107,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.238,-2.172,0.934,,0.197,.,B,0.55,-1.1,3.542,,71.59,BHH,-2.143,0.520039,0.00561937,0.22614 kka2_1:1_P167N,kka2_1:1_167,Kka2,kka2_1:1,P00552,0.226177,NO,167,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-2.403,-3.993,1.59,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.520039,0.00543203,0.226177 beta-lactamase_156_A133L,beta-lactamase_156_133,TEM-1,beta-lactamase_156,P62593,0.226206,NO,133,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.186,-3.396,2.21,,,H,A,0.46,-0.86,0.805,,67.83,HHP,-0.988333,0.111618,0.00468022,0.226206 beta-lactamase_2500_C121V,beta-lactamase_2500_121,TEM-1,beta-lactamase_2500,P62593,0.226231,NO,121,C,V,CV,Special,Hydrophobic,5.07,5.60847,0.538465,192,121,117,-4,108.5,140,31.5,-0.953,-3.371,2.418,,,H,A,0.46,-0.81,1.174,,63.29,HOP,-1.46767,0.361275,0.000744322,0.226231 kka2_1:1_A41W,kka2_1:1_41,Kka2,kka2_1:1,P00552,0.22634,NO,41,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.879,-3.701,1.822,,0.184,.,B,0.46,-0.96,18.207,18.207,64.39,PHP,-2.477,0.520039,0.00543332,0.22634 beta-lactamase_39_K71A,beta-lactamase_39_71,TEM-1,beta-lactamase_39,P62593,0.226403,NO,71,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-0.8,-3.078,2.278,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.0495842,0.00103192,0.226403 beta-lactamase_2500_I285P,beta-lactamase_2500_285,TEM-1,beta-lactamase_2500,P62593,0.22641,NO,285,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.361275,0.101555,0.22641 kka2_1:4_N195F,kka2_1:4_195,Kka2,kka2_1:4,P00552,0.226414,NO,195,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-0.836,-4.344,3.508,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.168804,0.00276134,0.226414 kka2_1:8_T73P,kka2_1:8_73,Kka2,kka2_1:8,P00552,0.226441,NO,73,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.51,-4.057,1.547,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.100394,0.00628605,0.226441 kka2_1:8_T73P,kka2_1:8_73,Kka2,kka2_1:8,P00552,0.226441,NO,73,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.51,-4.057,1.547,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.100394,0.00628605,0.226441 beta-lactamase_625_D177A,beta-lactamase_625_177,TEM-1,beta-lactamase_625,P62593,0.226504,NO,177,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.967,-2.529,1.562,,0.006,T,L,0.75,-1.02,1.333,,64.69,BAP,-0.873667,0.213352,0.000864022,0.226504 beta-lactamase_E164H,beta-lactamase_164,TEM-1,beta-lactamase,P62593,0.226528,NO,164,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-0.948,-4.339,3.391,5.3334,0.011,T,B,1.62,-0.4,1.055,,64.69,HAO,-1.388,0.221079,0.00137286,0.226528 kka2_1:8_F206A,kka2_1:8_206,Kka2,kka2_1:8,P00552,0.226614,NO,206,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.349,-3.367,2.018,,0.006,E,B,1.62,-1.21,1.052,,63.64,OHH,-1.04,0.100394,0.00936868,0.226614 kka2_1:8_F206A,kka2_1:8_206,Kka2,kka2_1:8,P00552,0.226614,NO,206,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.349,-3.367,2.018,,0.006,E,B,1.62,-1.21,1.052,,63.64,OHH,-1.04,0.100394,0.00936868,0.226614 kka2_1:1_V75H,kka2_1:1_75,Kka2,kka2_1:1,P00552,0.226706,NO,75,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-2.06,-4.952,2.892,,0.042,.,B,0.44,-0.2,2.815,,71.59,OHO,-1.563,0.520039,0.00693733,0.226706 kka2_1:1_P194I,kka2_1:1_194,Kka2,kka2_1:1,P00552,0.226729,NO,194,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.846,-4.06,3.214,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.520039,0.00314194,0.226729 kka2_1:1_D159C,kka2_1:1_159,Kka2,kka2_1:1,P00552,0.22673,NO,159,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.82,-5.15,4.33,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.520039,0.0030485,0.22673 beta-lactamase_39_K71R,beta-lactamase_39_71,TEM-1,beta-lactamase_39,P62593,0.226744,NO,71,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-0.8,-3.033,2.233,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.0495842,0.00103192,0.226744 kka2_1:2_W69Y,kka2_1:2_69,Kka2,kka2_1:2,P00552,0.226764,NO,69,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-0.859,-2.519,1.66,,0.164,H,A,0.47,0.15,5.074,,38.64,PHH,-1.49967,0.295029,0.0012874,0.226764 kka2_1:1_T28G,kka2_1:1_28,Kka2,kka2_1:1,P00552,0.226777,NO,28,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.883,-2.414,0.531,,0.353,S,B,0.22,2.02,1.12,,63.64,PPH,-1.74467,0.520039,0.00743084,0.226777 kka2_1:4_I207W,kka2_1:4_207,Kka2,kka2_1:4,P00552,0.226802,NO,207,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.175,-5.409,4.234,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.168804,0.00611824,0.226802 beta-lactamase_2500_L218N,beta-lactamase_2500_218,TEM-1,beta-lactamase_2500,P62593,0.226868,NO,218,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.391,-3.851,2.46,,,I,b,0.55,-0.53,9.151,9.151,74.48,OHH,-1.58867,0.361275,0.00618274,0.226868 beta-lactamase_0_M127L,beta-lactamase_0_127,TEM-1,beta-lactamase_0,P62593,0.226871,NO,127,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-2.251,-2.123,-0.128,,0.312,S,A,0.55,0.32,9.35,9.35,72.73,PHP,-1.40433,0.0500837,0.00437927,0.226871 Pab1_F173A,Pab1_173,Pab1,Pab1,P04147,0.22694,NO,173,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.477,-3.191,1.714,,,E,B,0.87,-0.16,1.636,,63.26,BHA,-1.36967,0.175299,0.00148779,0.22694 beta-lactamase_625_V72Q,beta-lactamase_625_72,TEM-1,beta-lactamase_625,P62593,0.226983,NO,72,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.658,-4.185,2.527,,,H,A,0.44,-1.03,0.981,,65.73,BHH,-1.32167,0.213352,0.00501194,0.226983 kka2_1:4_S32A,kka2_1:4_32,Kka2,kka2_1:4,P00552,0.227015,NO,32,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-0.804,-2.656,1.852,,0.768,S,b,0.27,3.75,,,,OPA,-1.74533,0.168804,0.00149998,0.227015 kka2_1:1_F263Q,kka2_1:1_263,Kka2,kka2_1:1,P00552,0.22707,NO,263,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-0.911,-4.376,3.465,,0.006,G,A,0.58,-0.12,2.284,,45.83,AHH,-0.92,0.520039,0.0172454,0.22707 beta-lactamase_2500_C121T,beta-lactamase_2500_121,TEM-1,beta-lactamase_2500,P62593,0.227122,NO,121,C,T,CT,Special,Polar,5.07,5.6,0.53,149,121,119,-2,108.5,116.1,7.6,-0.953,-3.447,2.494,,,H,A,0.46,-0.81,1.174,,63.29,HOP,-1.46767,0.361275,0.000744322,0.227122 kka2_1:8_G205K,kka2_1:8_205,Kka2,kka2_1:8,P00552,0.227133,NO,205,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.596,-3.71,3.114,,,E,b,0.75,-1.05,,,,POH,-1.09933,0.100394,0.00221855,0.227133 kka2_1:8_G205K,kka2_1:8_205,Kka2,kka2_1:8,P00552,0.227133,NO,205,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.596,-3.71,3.114,,,E,b,0.75,-1.05,,,,POH,-1.09933,0.100394,0.00221855,0.227133 beta-lactamase_625_I258N,beta-lactamase_625_258,TEM-1,beta-lactamase_625,P62593,0.227199,NO,258,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.213352,0.007931,0.227199 beta-lactamase_625_W208K,beta-lactamase_625_208,TEM-1,beta-lactamase_625,P62593,0.227219,NO,208,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-0.818,-3.907,3.089,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.213352,0.00126609,0.227219 beta-lactamase_625_K232T,beta-lactamase_625_232,TEM-1,beta-lactamase_625,P62593,0.227242,NO,232,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.012,-3.464,2.452,,,E,B,2.34,-1.1,1.992,,65.03,ABP,-1.238,0.213352,0.00313441,0.227242 kka2_1:4_Y218E,kka2_1:4_218,Kka2,kka2_1:4,P00552,0.22725,NO,218,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-1.438,-3.729,2.291,,0.122,H,A,0.21,-0.69,1.022,,56.06,BHP,-1.17533,0.168804,0.0126098,0.22725 beta-lactamase_2500_A230Q,beta-lactamase_2500_230,TEM-1,beta-lactamase_2500,P62593,0.227289,NO,230,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.154,-4.025,2.871,,0.01,E,B,0.46,-1.17,1.171,,50,HHA,-1.079,0.361275,0.00516841,0.227289 kka2_1:1_T125C,kka2_1:1_125,Kka2,kka2_1:1,P00552,0.227347,NO,125,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.622,-5.084,2.462,,0.791,T,A,0.22,0.33,1.972,,92.05,BPH,-1.56933,0.520039,0.00821755,0.227347 beta-lactamase_2500_S57P,beta-lactamase_2500_57,TEM-1,beta-lactamase_2500,P62593,0.227391,NO,57,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.918,-3.952,2.034,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.361275,0.00492804,0.227391 kka2_1:2_I196A,kka2_1:2_196,Kka2,kka2_1:2,P00552,0.2274,NO,196,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-2.115,-3.338,1.223,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.295029,0.0107273,0.2274 beta-lactamase_T107Y,beta-lactamase_107,TEM-1,beta-lactamase,P62593,0.227416,NO,107,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.117,-4.214,3.097,5.23432,,G,A,2.12,-0.06,3.676,,67.83,HPA,-1.265,0.221079,0.00239347,0.227416 beta-lactamase_2500_I244Q,beta-lactamase_2500_244,TEM-1,beta-lactamase_2500,P62593,0.227435,NO,244,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.555,-4.255,2.7,,,E,B,0.48,-0.84,1.683,,77.62,OHH,-1.385,0.361275,0.00605379,0.227435 kka2_1:2_L94S,kka2_1:2_94,Kka2,kka2_1:2,P00552,0.227445,NO,94,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.618,-3.596,1.978,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.295029,0.00520888,0.227445 kka2_1:8_I141H,kka2_1:8_141,Kka2,kka2_1:8,P00552,0.227479,NO,141,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.495,-5.058,3.563,,0.068,H,A,1.52,-0.01,2.144,,92.05,BHA,-1.689,0.100394,0.00744745,0.227479 kka2_1:8_I141H,kka2_1:8_141,Kka2,kka2_1:8,P00552,0.227479,NO,141,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.495,-5.058,3.563,,0.068,H,A,1.52,-0.01,2.144,,92.05,BHA,-1.689,0.100394,0.00744745,0.227479 kka2_1:1_L126H,kka2_1:1_126,Kka2,kka2_1:1,P00552,0.227513,NO,126,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.246,-4.997,3.751,,0.285,S,B,0.55,0.12,0.302,,51.89,PHA,-1.744,0.520039,0.0066485,0.227513 kka2_1:1_E169Y,kka2_1:1_169,Kka2,kka2_1:1,P00552,0.227546,NO,169,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.996,-4.385,2.389,,0.422,H,A,1.04,0.3,7.546,7.546,65.53,HAH,-1.755,0.520039,0.00730086,0.227546 beta-lactamase_39_T69D,beta-lactamase_39_69,TEM-1,beta-lactamase_39,P62593,0.227577,NO,69,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-0.973,-3.534,2.561,,,G,A,0.22,-1.24,4.194,,93.01,PPH,-1.01833,0.0495842,0.00127498,0.227577 kka2_1:1_H188T,kka2_1:1_188,Kka2,kka2_1:1,P00552,0.227583,NO,188,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-0.913,-3.673,2.76,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.520039,0.00273139,0.227583 beta-lactamase_156_G243Y,beta-lactamase_156_243,TEM-1,beta-lactamase_156,P62593,0.2276,NO,243,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.532,,,,,E,B,0.77,-1.24,2.866,,50,BOH,-1.46867,0.111618,0.00464034,0.2276 kka2_1:1_C77H,kka2_1:1_77,Kka2,kka2_1:1,P00552,0.227747,NO,77,C,H,CH,Special,PositiveCharge,5.07,7.59,2.52,174,121,155,34,108.5,153.2,44.7,-1.477,-4.937,3.46,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.520039,0.00441216,0.227747 beta-lactamase_2500_A34H,beta-lactamase_2500_34,TEM-1,beta-lactamase_2500,P62593,0.227786,NO,34,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.059,-4.883,2.824,,,H,A,0.46,-0.54,2.921,,73.78,AHA,-1.74967,0.361275,0.00407913,0.227786 kka2_1:4_I228S,kka2_1:4_228,Kka2,kka2_1:4,P00552,0.227794,NO,228,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.142,-3.711,2.569,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.168804,0.00458834,0.227794 kka2_1:2_R226P,kka2_1:2_226,Kka2,kka2_1:2,P00552,0.227798,NO,226,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.392,-4.085,2.693,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.295029,0.0108032,0.227798 kka2_1:1_E161Y,kka2_1:1_161,Kka2,kka2_1:1,P00552,0.227821,NO,161,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.581,-4.394,2.813,,0.829,G,A,1.04,2.24,1.612,,92.05,AAB,-1.861,0.520039,0.00760103,0.227821 kka2_1:2_N195V,kka2_1:2_195,Kka2,kka2_1:2,P00552,0.227861,NO,195,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-0.836,-3.805,2.969,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.295029,0.00276134,0.227861 beta-lactamase_2500_I45R,beta-lactamase_2500_45,TEM-1,beta-lactamase_2500,P62593,0.227909,NO,45,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-2.421,-4.043,1.622,,,E,B,0.48,-0.3,3.793,,77.62,HHA,-2.30267,0.361275,0.00452842,0.227909 beta-lactamase_V117R,beta-lactamase_117,TEM-1,beta-lactamase,P62593,0.227916,NO,117,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.53,-4.17,2.64,5.33594,,H,A,1.19,-0.34,1.182,,65.03,PHB,-1.741,0.221079,0.00467906,0.227916 kka2_1:1_E235C,kka2_1:1_235,Kka2,kka2_1:1,P00552,0.227925,NO,235,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.955,-5.156,3.201,,0.631,H,A,1.52,0.12,8.521,,65.53,OAH,-2.07267,0.520039,0.0102806,0.227925 beta-lactamase_625_G142P,beta-lactamase_625_142,TEM-1,beta-lactamase_625,P62593,0.227971,NO,142,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.707,-3.877,3.17,,0.034,,p,0.29,-0.64,1.35,,64.69,OOO,-0.834,0.213352,0.00060149,0.227971 kka2_1:2_D208S,kka2_1:2_208,Kka2,kka2_1:2,P00552,0.227974,NO,208,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.708,-3.189,2.481,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.295029,0.00212588,0.227974 kka2_1:4_F263R,kka2_1:4_263,Kka2,kka2_1:4,P00552,0.227981,NO,263,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-0.911,-4.185,3.274,,0.006,G,A,0.58,-0.12,2.284,,45.83,AHH,-0.92,0.168804,0.0172454,0.227981 kka2_1:1_I141E,kka2_1:1_141,Kka2,kka2_1:1,P00552,0.228027,NO,141,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.495,-3.998,2.503,,0.068,H,A,0.48,-0.01,7.546,7.546,92.05,BHA,-1.689,0.520039,0.00744745,0.228027 kka2_1:2_A229F,kka2_1:2_229,Kka2,kka2_1:2,P00552,0.228094,NO,229,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.739,-4.384,2.645,,0.32,H,A,0.46,-0.7,6.549,,63.64,HHA,-1.851,0.295029,0.00942138,0.228094 E1_Ubiquitin_G76P,E1_Ubiquitin_76,Uba1,E1_Ubiquitin,P0CG63,0.228117,NO,76,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.999,-3.843,2.844,,0.23,,B,0.75,0.08,1.702,,83.73,OOO,-0.999,0.18783,0.00125575,0.228117 kka2_1:1_S32L,kka2_1:1_32,Kka2,kka2_1:1,P00552,0.22812,NO,32,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-0.804,-3.386,2.582,,0.768,S,b,0.27,3.75,,,,OPA,-1.74533,0.520039,0.00149998,0.22812 kka2_1:2_I115Y,kka2_1:2_115,Kka2,kka2_1:2,P00552,0.228124,NO,115,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.606,-4.097,2.491,,0.105,H,A,0.48,-1.18,0.878,,65.53,PHH,-2.205,0.295029,0.00836567,0.228124 beta-lactamase_2500_R257G,beta-lactamase_2500_257,TEM-1,beta-lactamase_2500,P62593,0.228152,NO,257,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.361275,0.00756629,0.228152 beta-lactamase_2500_L284Y,beta-lactamase_2500_284,TEM-1,beta-lactamase_2500,P62593,0.228153,NO,284,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.361275,0.0686156,0.228153 beta-lactamase_39_C121R,beta-lactamase_39_121,TEM-1,beta-lactamase_39,P62593,0.228219,NO,121,C,R,CR,Special,PositiveCharge,5.07,6.34148,1.27148,180,121,174,53,108.5,173.4,64.9,-0.953,-2.762,1.809,,,H,A,0.46,-0.81,7.644,,63.29,HOP,-1.46767,0.0495842,0.000744322,0.228219 kka2_1:4_P194M,kka2_1:4_194,Kka2,kka2_1:4,P00552,0.228225,NO,194,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.846,-4.773,3.927,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.168804,0.00314194,0.228225 kka2_1:1_L243F,kka2_1:1_243,Kka2,kka2_1:1,P00552,0.228242,NO,243,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-2.651,-4.372,1.721,,0.277,H,A,0.55,-0.67,4.334,,92.05,HHH,-2.03767,0.520039,0.00884927,0.228242 beta-lactamase_625_V260K,beta-lactamase_625_260,TEM-1,beta-lactamase_625,P62593,0.228272,NO,260,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.213352,0.00471757,0.228272 kka2_1:2_E96M,kka2_1:2_96,Kka2,kka2_1:2,P00552,0.228318,NO,96,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.573,-4.64,2.067,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.295029,0.00369441,0.228318 kka2_1:1_A172C,kka2_1:1_172,Kka2,kka2_1:1,P00552,0.228434,NO,172,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.757,-5.069,3.312,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.520039,0.0079265,0.228434 beta-lactamase_2500_L218Y,beta-lactamase_2500_218,TEM-1,beta-lactamase_2500,P62593,0.228448,NO,218,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.391,-4.087,2.696,,,I,b,0.55,-0.53,9.151,9.151,74.48,OHH,-1.58867,0.361275,0.00618274,0.228448 beta-lactamase_625_A123R,beta-lactamase_625_123,TEM-1,beta-lactamase_625,P62593,0.228462,NO,123,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.834,-3.776,2.942,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.213352,0.0010157,0.228462 kka2_1:2_G74L,kka2_1:2_74,Kka2,kka2_1:2,P00552,0.228491,NO,74,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.18,-3.872,2.692,,0.621,T,l,0.75,0.2,1.446,,64.39,POH,-1.91667,0.295029,0.00587035,0.228491 kka2_1:2_A119D,kka2_1:2_119,Kka2,kka2_1:2,P00552,0.22851,NO,119,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.073,-3.713,2.64,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.295029,0.00441074,0.22851 kka2_1:8_V36H,kka2_1:8_36,Kka2,kka2_1:8,P00552,0.228514,NO,36,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-0.898,-4.978,4.08,,0.292,E,B,1.48,0.21,0.938,,52.27,HHH,-1.484,0.100394,0.00245633,0.228514 kka2_1:8_V36H,kka2_1:8_36,Kka2,kka2_1:8,P00552,0.228514,NO,36,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-0.898,-4.978,4.08,,0.292,E,B,1.48,0.21,0.938,,52.27,HHH,-1.484,0.100394,0.00245633,0.228514 beta-lactamase_2500_G234F,beta-lactamase_2500_234,TEM-1,beta-lactamase_2500,P62593,0.228533,NO,234,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.62,-4.292,3.672,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.361275,0.000889577,0.228533 beta-lactamase_625_N130P,beta-lactamase_625_130,TEM-1,beta-lactamase_625,P62593,0.228595,NO,130,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-0.798,-3.88,3.082,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.213352,0.000683376,0.228595 beta-lactamase_39_D129Q,beta-lactamase_39_129,TEM-1,beta-lactamase_39,P62593,0.228615,NO,129,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.816,-3.637,2.821,,,,B,0.75,-0.69,0.56,,34.97,PAP,-0.818,0.0495842,0.00109178,0.228615 beta-lactamase_156_A246D,beta-lactamase_156_246,TEM-1,beta-lactamase_156,P62593,0.228672,NO,246,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.121,-4.086,1.965,,0.01,E,B,0.46,-1.01,1.959,,73.78,HHH,-1.55633,0.111618,0.00569458,0.228672 kka2_1:8_A222L,kka2_1:8_222,Kka2,kka2_1:8,P00552,0.228686,NO,222,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.725,-3.161,2.436,,,H,A,1.04,-1.21,,,,HHH,-1.10833,0.100394,0.00207657,0.228686 kka2_1:8_A222L,kka2_1:8_222,Kka2,kka2_1:8,P00552,0.228686,NO,222,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.725,-3.161,2.436,,,H,A,1.04,-1.21,,,,HHH,-1.10833,0.100394,0.00207657,0.228686 kka2_1:8_C77K,kka2_1:8_77,Kka2,kka2_1:8,P00552,0.228686,NO,77,C,K,CK,Special,PositiveCharge,5.07,9.74,4.67,202,121,146,25,108.5,168.6,60.1,-1.477,-3.834,2.357,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.100394,0.00441216,0.228686 kka2_1:8_C77K,kka2_1:8_77,Kka2,kka2_1:8,P00552,0.228686,NO,77,C,K,CK,Special,PositiveCharge,5.07,9.74,4.67,202,121,146,25,108.5,168.6,60.1,-1.477,-3.834,2.357,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.100394,0.00441216,0.228686 PSD95pdz3_I341G,PSD95pdz3_341,PSD95pdz3,PSD95pdz3,P31016,0.228764,NO,341,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.63,-3.49,1.86,5.73946,,,,,10.3187,,,,HHH,-1.50033,0.0758425,0.000824087,0.228764 kka2_1:4_L170H,kka2_1:4_170,Kka2,kka2_1:4,P00552,0.228825,NO,170,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.28,-5.007,3.727,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.168804,0.00730791,0.228825 Pab1_F173S,Pab1_173,Pab1,Pab1,P04147,0.228865,NO,173,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.477,-3.499,2.022,,,E,B,0.87,-0.16,1.636,,63.26,BHA,-1.36967,0.175299,0.00148779,0.228865 kka2_1:1_E182H,kka2_1:1_182,Kka2,kka2_1:1,P00552,0.228963,NO,182,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.516,-2.568,1.052,,0.326,,B,1.52,0.75,14.547,14.547,65.53,OAA,-1.806,0.520039,0.00641548,0.228963 beta-lactamase_39_L47P,beta-lactamase_39_47,TEM-1,beta-lactamase_39,P62593,0.228965,NO,47,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.876,-4.153,2.277,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.0495842,0.00439844,0.228965 kka2_1:1_H188S,kka2_1:1_188,Kka2,kka2_1:1,P00552,0.229003,NO,188,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-0.913,-3.412,2.499,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.520039,0.00273139,0.229003 kka2_1:1_F206T,kka2_1:1_206,Kka2,kka2_1:1,P00552,0.229019,NO,206,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.349,-3.71,2.361,,0.006,E,B,0.58,-1.21,0.978,,63.64,OHH,-1.04,0.520039,0.00936868,0.229019 beta-lactamase_2500_L55P,beta-lactamase_2500_55,TEM-1,beta-lactamase_2500,P62593,0.229049,NO,55,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.86,-4.226,2.366,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.361275,0.00403741,0.229049 beta-lactamase_2500_T27F,beta-lactamase_2500_27,TEM-1,beta-lactamase_2500,P62593,0.229165,NO,27,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.905,-2.968,1.063,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.361275,0.00306559,0.229165 kka2_1:8_F264D,kka2_1:8_264,Kka2,kka2_1:8,P00552,0.229203,NO,264,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.02,-4.038,3.018,,0.296,,?,1.62,0.02,1.553,,71.59,HHO,-0.9655,0.100394,,0.229203 kka2_1:8_F264D,kka2_1:8_264,Kka2,kka2_1:8,P00552,0.229203,NO,264,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.02,-4.038,3.018,,0.296,,?,1.62,0.02,1.553,,71.59,HHO,-0.9655,0.100394,,0.229203 kka2_1:8_Y218K,kka2_1:8_218,Kka2,kka2_1:8,P00552,0.229203,NO,218,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-1.438,-3.819,2.381,,0.122,H,A,1.25,-0.69,2.923,,56.06,BHP,-1.17533,0.100394,0.0126098,0.229203 kka2_1:8_Y218K,kka2_1:8_218,Kka2,kka2_1:8,P00552,0.229203,NO,218,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-1.438,-3.819,2.381,,0.122,H,A,1.25,-0.69,2.923,,56.06,BHP,-1.17533,0.100394,0.0126098,0.229203 kka2_1:1_R226M,kka2_1:1_226,Kka2,kka2_1:1,P00552,0.229216,NO,226,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.392,-4.698,3.306,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.520039,0.0108032,0.229216 kka2_1:1_E262A,kka2_1:1_262,Kka2,kka2_1:1,P00552,0.229276,NO,262,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-0.829,-3.129,2.3,,0.059,G,A,1.04,-0.18,0.837,,42.42,AAH,-0.816,0.520039,0.0191586,0.229276 kka2_1:4_W69N,kka2_1:4_69,Kka2,kka2_1:4,P00552,0.229279,NO,69,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-0.859,-4.344,3.485,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.168804,0.0012874,0.229279 kka2_1:2_Y22Q,kka2_1:2_22,Kka2,kka2_1:2,P00552,0.229284,NO,22,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-1.583,-4.105,2.522,,0.122,.,B,0.21,-0.8,1.838,,65.53,OHA,-1.80333,0.295029,0.00598977,0.229284 kka2_1:2_D261E,kka2_1:2_261,Kka2,kka2_1:2,P00552,0.229286,NO,261,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.708,-2.793,2.085,,0.146,G,A,0.75,-0.33,,,,HAA,-0.759333,0.295029,0.0224846,0.229286 beta-lactamase_156_W208P,beta-lactamase_156_208,TEM-1,beta-lactamase_156,P62593,0.229292,NO,208,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-0.818,-4.33,3.512,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.111618,0.00126609,0.229292 kka2_1:1_M148Y,kka2_1:1_148,Kka2,kka2_1:1,P00552,0.229296,NO,148,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.847,-4.225,2.378,,0.268,H,A,1.59,0.71,4.618,,64.39,BHA,-1.65467,0.520039,0.00982664,0.229296 beta-lactamase_2500_A247D,beta-lactamase_2500_247,TEM-1,beta-lactamase_2500,P62593,0.229308,NO,247,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.361275,0.00611275,0.229308 beta-lactamase_2500_A123W,beta-lactamase_2500_123,TEM-1,beta-lactamase_2500,P62593,0.229326,NO,123,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.834,-5.348,4.514,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.361275,0.0010157,0.229326 beta-lactamase_625_C75Y,beta-lactamase_625_75,TEM-1,beta-lactamase_625,P62593,0.229367,NO,75,C,Y,CY,Special,Hydrophobic,5.07,5.66,0.59,194,121,181,60,108.5,193.6,85.1,-1.245,-4.265,3.02,,,H,A,0.46,-0.87,2.141,,50,HOO,-1.24333,0.213352,0.0034616,0.229367 kka2_1:1_G99M,kka2_1:1_99,Kka2,kka2_1:1,P00552,0.229376,NO,99,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.596,-4.958,4.362,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.520039,0.00186055,0.229376 beta-lactamase_625_A230F,beta-lactamase_625_230,TEM-1,beta-lactamase_625,P62593,0.229384,NO,230,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.154,-4.217,3.063,,0.01,E,B,0.46,-1.17,0.777,,50,HHA,-1.079,0.213352,0.00516841,0.229384 kka2_1:1_G210K,kka2_1:1_210,Kka2,kka2_1:1,P00552,0.229411,NO,210,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.095,-3.696,2.601,,0.103,T,A,0.29,-0.62,14.483,14.483,50,OOB,-0.966667,0.520039,0.00598378,0.229411 kka2_1:4_W236P,kka2_1:4_236,Kka2,kka2_1:4,P00552,0.229436,NO,236,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-1.363,-4.32,2.957,,0.303,H,A,0.47,-0.76,2.277,,48.48,AHH,-1.81267,0.168804,0.0088796,0.229436 kka2_1:4_A117N,kka2_1:4_117,Kka2,kka2_1:4,P00552,0.229441,NO,117,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.828,-3.99,3.162,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.168804,0.00282984,0.229441 kka2_1:2_V84P,kka2_1:2_84,Kka2,kka2_1:2,P00552,0.229464,NO,84,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-2.279,-4.01,1.731,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.295029,0.00724019,0.229464 kka2_1:1_L212K,kka2_1:1_212,Kka2,kka2_1:1,P00552,0.229466,NO,212,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.904,-3.732,2.828,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.520039,0.0031426,0.229466 hsp90_S586W,hsp90_586,hsp90,hsp90,P02829,0.229481,NO,586,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.764,-4.251,0,4.65438,,,B,0.93,0.15,,,,HPH,-3.157,0.368192,0.000222939,0.229481 kka2_1:1_L39I,kka2_1:1_39,Kka2,kka2_1:1,P00552,0.229538,NO,39,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.223,-2.15,0.927,,,E,B,0.55,-1.21,0.925,,71.59,BHP,-1.69167,0.520039,0.00493618,0.229538 kka2_1:1_T73S,kka2_1:1_73,Kka2,kka2_1:1,P00552,0.229539,NO,73,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.51,-2.503,-0.007,,0.309,H,A,0.22,0.35,4.126,,56.06,PPO,-2.02333,0.520039,0.00628605,0.229539 kka2_1:1_H135E,kka2_1:1_135,Kka2,kka2_1:1,P00552,0.229544,NO,135,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-1.331,-3.297,1.966,,0.071,.,a,0.17,0.65,3.574,,53.03,ABP,-1.77367,0.520039,0.00532566,0.229544 beta-lactamase_39_V78P,beta-lactamase_39_78,TEM-1,beta-lactamase_39,P62593,0.229575,NO,78,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.459,-4.126,2.667,,,H,A,0.44,-0.47,1.132,,63.64,HHH,-1.17833,0.0495842,0.00492501,0.229575 kka2_1:2_D190N,kka2_1:2_190,Kka2,kka2_1:2,P00552,0.229576,NO,190,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.708,-3.251,2.543,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.295029,0.00247989,0.229576 beta-lactamase_156_L167D,beta-lactamase_156_167,TEM-1,beta-lactamase_156,P62593,0.229624,NO,167,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.138,-4.03,2.892,,0.015,G,A,0.55,-0.63,0.4,,64.69,AHP,-1.30767,0.111618,0.00303566,0.229624 kka2_1:1_R217N,kka2_1:1_217,Kka2,kka2_1:1,P00552,0.229628,NO,217,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.158,-3.736,2.578,,0.252,T,A,1.2,-0.59,0.381,,52.27,ABH,-1.127,0.520039,0.0047191,0.229628 kka2_1:1_L174I,kka2_1:1_174,Kka2,kka2_1:1,P00552,0.229652,NO,174,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.952,-3.013,2.061,,,H,A,0.55,-0.31,13.276,13.276,51.89,BHB,-2.08533,0.520039,0.00438501,0.229652 beta-lactamase_625_D129R,beta-lactamase_625_129,TEM-1,beta-lactamase_625,P62593,0.229663,NO,129,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.816,-3.896,3.08,,,,B,0.75,-0.69,0.171,,34.97,PAP,-0.818,0.213352,0.00109178,0.229663 kka2_1:1_A222N,kka2_1:1_222,Kka2,kka2_1:1,P00552,0.229664,NO,222,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.725,-3.926,3.201,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.520039,0.00207657,0.229664 kka2_1:4_M197A,kka2_1:4_197,Kka2,kka2_1:4,P00552,0.229699,NO,197,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.707,-3.22,1.513,,0.121,E,B,0.55,-1.19,0.415,,65.53,HHH,-1.847,0.168804,0.00921295,0.229699 kka2_1:8_A34W,kka2_1:8_34,Kka2,kka2_1:8,P00552,0.229718,NO,34,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.928,-5.383,4.455,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.100394,0.00343484,0.229718 kka2_1:8_A34W,kka2_1:8_34,Kka2,kka2_1:8,P00552,0.229718,NO,34,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.928,-5.383,4.455,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.100394,0.00343484,0.229718 kka2_1:1_T72V,kka2_1:1_72,Kka2,kka2_1:1,P00552,0.229756,NO,72,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.38,-3.703,1.323,,0.784,H,A,0.22,0.29,10.43,10.43,65.53,HPP,-2.238,0.520039,0.00750756,0.229756 kka2_1:1_F263Y,kka2_1:1_263,Kka2,kka2_1:1,P00552,0.22976,NO,263,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-0.911,-3.189,2.278,,0.006,G,A,0.58,-0.12,2.284,,45.83,AHH,-0.92,0.520039,0.0172454,0.22976 kka2_1:2_L241N,kka2_1:2_241,Kka2,kka2_1:2,P00552,0.229769,NO,241,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.158,-4.222,3.064,,0.08,H,A,0.55,-0.82,1.598,,63.26,HHH,-1.58533,0.295029,0.0117299,0.229769 kka2_1:1_L93H,kka2_1:1_93,Kka2,kka2_1:1,P00552,0.229804,NO,93,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.815,-4.864,4.049,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.520039,0.00131498,0.229804 beta-lactamase_156_G240L,beta-lactamase_156_240,TEM-1,beta-lactamase_156,P62593,0.229807,NO,240,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.111618,0.00591201,0.229807 beta-lactamase_625_K30P,beta-lactamase_625_30,TEM-1,beta-lactamase_625,P62593,0.229878,NO,30,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-2.307,-3.871,1.564,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.213352,0.00448593,0.229878 E1_Ubiquitin_G76D,E1_Ubiquitin_76,Uba1,E1_Ubiquitin,P0CG63,0.229885,NO,76,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.999,-3.467,2.468,,0.23,,B,0.75,0.08,1.702,,83.73,OOO,-0.999,0.18783,0.00125575,0.229885 beta-lactamase_625_G236Y,beta-lactamase_625_236,TEM-1,beta-lactamase_625,P62593,0.229886,NO,236,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.784,-4.387,3.603,,0.241,,b,0.29,-0.59,3.506,,64.69,HOO,-1.025,0.213352,0.00162372,0.229886 kka2_1:8_M197A,kka2_1:8_197,Kka2,kka2_1:8,P00552,0.229889,NO,197,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.707,-3.22,1.513,,0.121,E,B,1.59,-1.19,4.408,,65.53,HHH,-1.847,0.100394,0.00921295,0.229889 kka2_1:8_M197A,kka2_1:8_197,Kka2,kka2_1:8,P00552,0.229889,NO,197,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.707,-3.22,1.513,,0.121,E,B,1.59,-1.19,4.408,,65.53,HHH,-1.847,0.100394,0.00921295,0.229889 beta-lactamase_156_S233R,beta-lactamase_156_233,TEM-1,beta-lactamase_156,P62593,0.229915,NO,233,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.886,-3.819,1.933,,0.016,E,B,0.27,-1.01,4.111,,77.62,BPO,-1.17267,0.111618,0.00311415,0.229915 kka2_1:1_F264Q,kka2_1:1_264,Kka2,kka2_1:1,P00552,0.229999,NO,264,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.02,-4.325,3.305,,0.296,.,?,0.58,0.02,2.303,,71.59,HHNA,-0.9655,0.520039,,0.229999 kka2_1:4_E262M,kka2_1:4_262,Kka2,kka2_1:4,P00552,0.229999,NO,262,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-0.829,-4.701,3.872,,0.059,G,A,1.04,-0.18,2.383,,42.42,AAH,-0.816,0.168804,0.0191586,0.229999 beta-lactamase_2500_I285E,beta-lactamase_2500_285,TEM-1,beta-lactamase_2500,P62593,0.230015,NO,285,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.361275,0.101555,0.230015 beta-lactamase_2500_W227C,beta-lactamase_2500_227,TEM-1,beta-lactamase_2500,P62593,0.230041,NO,227,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-0.982,-4.932,3.95,,0.272,,B,0.47,-0.29,1.37,,74.48,OHH,-1.595,0.361275,0.00226019,0.230041 beta-lactamase_39_I280N,beta-lactamase_39_280,TEM-1,beta-lactamase_39,P62593,0.230077,NO,280,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.0495842,0.0530888,0.230077 beta-lactamase_156_D129L,beta-lactamase_156_129,TEM-1,beta-lactamase_156,P62593,0.230196,NO,129,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.816,-3.806,2.99,,,,B,0.75,-0.69,1.924,,34.97,PAP,-0.818,0.111618,0.00109178,0.230196 beta-lactamase_2500_V42K,beta-lactamase_2500_42,TEM-1,beta-lactamase_2500,P62593,0.230198,NO,42,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.564,-3.817,2.253,,0.017,E,B,0.44,-0.51,1.86,,63.99,BHO,-1.042,0.361275,0.00404515,0.230198 beta-lactamase_625_T107H,beta-lactamase_625_107,TEM-1,beta-lactamase_625,P62593,0.230232,NO,107,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.117,-4.67,3.553,,,G,A,0.22,-0.06,3.676,,67.83,HPA,-1.265,0.213352,0.00239347,0.230232 beta-lactamase_2500_R162L,beta-lactamase_2500_162,TEM-1,beta-lactamase_2500,P62593,0.230241,NO,162,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.016,-2.541,1.525,,0.124,S,B,1.2,-0.37,6.199,,64.69,ABH,-1.25,0.361275,0.000561334,0.230241 kka2_1:4_W91A,kka2_1:4_91,Kka2,kka2_1:4,P00552,0.230263,NO,91,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-1.178,-3.5,2.322,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.168804,0.00358653,0.230263 kka2_1:1_S104D,kka2_1:1_104,Kka2,kka2_1:1,P00552,0.230273,NO,104,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.436,-2.848,1.412,,0.536,T,A,0.27,-1.11,5.49,,63.64,HPP,-1.91433,0.520039,0.00555207,0.230273 kka2_1:4_D183W,kka2_1:4_183,Kka2,kka2_1:4,P00552,0.230289,NO,183,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.204,-5.594,4.39,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.168804,0.00426304,0.230289 beta-lactamase_2500_S241M,beta-lactamase_2500_241,TEM-1,beta-lactamase_2500,P62593,0.230295,NO,241,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.361275,0.00452736,0.230295 kka2_1:2_R147W,kka2_1:2_147,Kka2,kka2_1:2,P00552,0.230301,NO,147,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.123,-5.411,4.288,,0.094,H,A,1.2,0.97,0.425,,64.02,PBH,-1.98267,0.295029,0.00549168,0.230301 kka2_1:2_S32A,kka2_1:2_32,Kka2,kka2_1:2,P00552,0.230332,NO,32,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-0.804,-2.656,1.852,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.295029,0.00149998,0.230332 kka2_1:8_G210F,kka2_1:8_210,Kka2,kka2_1:8,P00552,0.230404,NO,210,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.095,-4.324,3.229,,0.103,T,A,0.75,-0.62,2.687,,50,OOB,-0.966667,0.100394,0.00598378,0.230404 kka2_1:8_G210F,kka2_1:8_210,Kka2,kka2_1:8,P00552,0.230404,NO,210,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.095,-4.324,3.229,,0.103,T,A,0.75,-0.62,2.687,,50,OOB,-0.966667,0.100394,0.00598378,0.230404 beta-lactamase_V117W,beta-lactamase_117,TEM-1,beta-lactamase,P62593,0.230437,NO,117,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.53,-5.228,3.698,5.33594,,H,A,1.19,-0.34,1.182,,65.03,PHB,-1.741,0.221079,0.00467906,0.230437 kka2_1:2_V49D,kka2_1:2_49,Kka2,kka2_1:2,P00552,0.230437,NO,49,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.614,-4.094,2.48,,,E,B,0.44,-0.77,1.233,,64.39,HHB,-1.3,0.295029,0.00615685,0.230437 beta-lactamase_156_L284P,beta-lactamase_156_284,TEM-1,beta-lactamase_156,P62593,0.230536,NO,284,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.111618,0.0686156,0.230536 kka2_1:4_Y218G,kka2_1:4_218,Kka2,kka2_1:4,P00552,0.230548,NO,218,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-1.438,-3.625,2.187,,0.122,H,A,0.21,-0.69,1.022,,56.06,BHP,-1.17533,0.168804,0.0126098,0.230548 beta-lactamase_625_P65R,beta-lactamase_625_65,TEM-1,beta-lactamase_625,P62593,0.230572,NO,65,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.894,-3.951,3.057,,0.098,E,B,0.52,-0.62,0.3,,40.56,HOH,-1.03233,0.213352,0.00152776,0.230572 kka2_1:8_F264A,kka2_1:8_264,Kka2,kka2_1:8,P00552,0.230575,NO,264,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.02,-3.385,2.365,,0.296,,?,1.62,0.02,1.553,,71.59,HHO,-0.9655,0.100394,,0.230575 kka2_1:8_F264A,kka2_1:8_264,Kka2,kka2_1:8,P00552,0.230575,NO,264,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.02,-3.385,2.365,,0.296,,?,1.62,0.02,1.553,,71.59,HHO,-0.9655,0.100394,,0.230575 beta-lactamase_2500_L74S,beta-lactamase_2500_74,TEM-1,beta-lactamase_2500,P62593,0.230628,NO,74,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.296,-3.399,2.103,,,H,A,0.55,-0.91,0.746,,50,HHO,-1.34933,0.361275,0.00493255,0.230628 beta-lactamase_2500_I245H,beta-lactamase_2500_245,TEM-1,beta-lactamase_2500,P62593,0.230638,NO,245,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.361275,0.00391032,0.230638 kka2_1:1_F263I,kka2_1:1_263,Kka2,kka2_1:1,P00552,0.230721,NO,263,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-0.911,-3.319,2.408,,0.006,G,A,0.58,-0.12,2.284,,45.83,AHH,-0.92,0.520039,0.0172454,0.230721 kka2_1:1_H106W,kka2_1:1_106,Kka2,kka2_1:1,P00552,0.230739,NO,106,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-3.13,-3.81,0.68,,1.065,.,a,0.17,-0.95,2.53,,71.59,PBH,-2.10433,0.520039,0.00730778,0.230739 kka2_1:1_F263G,kka2_1:1_263,Kka2,kka2_1:1,P00552,0.230742,NO,263,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-0.911,-3.675,2.764,,0.006,G,A,0.58,-0.12,2.284,,45.83,AHH,-0.92,0.520039,0.0172454,0.230742 Pab1_I196K,Pab1_196,Pab1,Pab1,P04147,0.230776,NO,196,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.795,-3.642,1.847,,,,,,,2.013,,80.59,AHH,-1.44667,0.175299,0.0016933,0.230776 kka2_1:2_A237I,kka2_1:2_237,Kka2,kka2_1:2,P00552,0.230782,NO,237,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.12,-2.296,0.176,,0.068,H,A,0.46,-0.71,2.369,,92.05,HHA,-2.10433,0.295029,0.012257,0.230782 kka2_1:4_D216M,kka2_1:4_216,Kka2,kka2_1:4,P00552,0.230805,NO,216,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.785,-4.956,4.171,,0.018,E,B,0.75,-0.51,0.112,,19.32,HAB,-0.970333,0.168804,0.00229969,0.230805 kka2_1:2_W236F,kka2_1:2_236,Kka2,kka2_1:2,P00552,0.230837,NO,236,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-1.363,-2.652,1.289,,0.303,H,A,1.51,-0.76,5.58,,48.48,AHH,-1.81267,0.295029,0.0088796,0.230837 Pab1_F173R,Pab1_173,Pab1,Pab1,P04147,0.230876,NO,173,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.477,-3.94,2.463,,,E,B,0.87,-0.16,1.636,,63.26,BHA,-1.36967,0.175299,0.00148779,0.230876 kka2_1:1_D208C,kka2_1:1_208,Kka2,kka2_1:1,P00552,0.230881,NO,208,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.708,-5.115,4.407,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.520039,0.00212588,0.230881 beta-lactamase_156_A133I,beta-lactamase_156_133,TEM-1,beta-lactamase_156,P62593,0.23092,NO,133,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.186,-3.823,2.637,,,H,A,0.46,-0.86,0.805,,67.83,HHP,-0.988333,0.111618,0.00468022,0.23092 kka2_1:2_C77P,kka2_1:2_77,Kka2,kka2_1:2,P00552,0.230929,NO,77,C,P,CP,Special,Special,5.07,6.3,1.23,169,121,115,-6,108.5,112.7,4.2,-1.477,-4.052,2.575,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.295029,0.00441216,0.230929 kka2_1:4_E231P,kka2_1:4_231,Kka2,kka2_1:4,P00552,0.230936,NO,231,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.002,-3.957,1.955,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.168804,0.00732383,0.230936 beta-lactamase_2500_P250W,beta-lactamase_2500_250,TEM-1,beta-lactamase_2500,P62593,0.23097,NO,250,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.361275,0.00550899,0.23097 hsp90_A587F,hsp90_587,hsp90,hsp90,P02829,0.231011,NO,587,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.456,-3.22,0,4.91216,0.049,H,A,0.55,-0.02,,,,PHP,-2.757,0.368192,0.000222939,0.231011 beta-lactamase_156_D155F,beta-lactamase_156_155,TEM-1,beta-lactamase_156,P62593,0.231055,NO,155,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.889,-4.341,3.452,,0.049,,B,0.75,-0.9,0.315,,64.69,OAB,-1.62267,0.111618,0.00135315,0.231055 beta-lactamase_625_C121E,beta-lactamase_625_121,TEM-1,beta-lactamase_625,P62593,0.231168,NO,121,C,E,CE,Special,negativeCharge,5.07,3.22,-1.85,170,121,147,26,108.5,138.4,29.9,-0.953,-3.987,3.034,,,H,A,0.46,-0.81,1.143,,63.29,HOP,-1.46767,0.213352,0.000744322,0.231168 beta-lactamase_2500_N134T,beta-lactamase_2500_134,TEM-1,beta-lactamase_2500,P62593,0.231197,NO,134,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-0.879,-3.245,2.366,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.361275,0.000644786,0.231197 kka2_1:1_G30T,kka2_1:1_30,Kka2,kka2_1:1,P00552,0.231216,NO,30,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.596,-3.675,3.079,,0.54,S,g,0.29,3.76,,,,HOO,-1.51133,0.520039,0.00159208,0.231216 kka2_1:1_Y257F,kka2_1:1_257,Kka2,kka2_1:1,P00552,0.23124,NO,257,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-1.064,-1.664,0.6,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.520039,0.0148191,0.23124 kka2_1:4_G233M,kka2_1:4_233,Kka2,kka2_1:4,P00552,0.231242,NO,233,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.748,-5.003,4.255,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.168804,0.00232366,0.231242 kka2_1:1_A79V,kka2_1:1_79,Kka2,kka2_1:1,P00552,0.231269,NO,79,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.368,-2.938,0.57,,0.563,.,B,0.46,-0.43,7.792,7.792,71.59,HHH,-1.752,0.520039,0.00664821,0.231269 beta-lactamase_625_N134R,beta-lactamase_625_134,TEM-1,beta-lactamase_625,P62593,0.231337,NO,134,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-0.879,-3.446,2.567,,0.138,H,A,0.61,-0.6,3.776,,53.15,HPH,-1.02233,0.213352,0.000644786,0.231337 kka2_1:1_I207S,kka2_1:1_207,Kka2,kka2_1:1,P00552,0.231452,NO,207,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.175,-3.726,2.551,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.520039,0.00611824,0.231452 beta-lactamase_L79W,beta-lactamase_79,TEM-1,beta-lactamase,P62593,0.231458,NO,79,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.842,-5.095,4.253,4.98681,0.007,H,A,1.07,-0.16,0.823,,50.35,HHP,-1.44333,0.221079,0.000947397,0.231458 beta-lactamase_625_T107R,beta-lactamase_625_107,TEM-1,beta-lactamase_625,P62593,0.231556,NO,107,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.117,-3.76,2.643,,,G,A,0.22,-0.06,3.676,,67.83,HPA,-1.265,0.213352,0.00239347,0.231556 beta-lactamase_W286S,beta-lactamase_286,TEM-1,beta-lactamase,P62593,0.231559,NO,286,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-1.111,-3.653,2.542,6.64456,0.492,,?,0.01,0.6,,,,BHX,-1.478,0.221079,,0.231559 beta-lactamase_2500_Y262G,beta-lactamase_2500_262,TEM-1,beta-lactamase_2500,P62593,0.231572,NO,262,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.361275,0.00853516,0.231572 kka2_1:1_F206G,kka2_1:1_206,Kka2,kka2_1:1,P00552,0.231593,NO,206,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.349,-3.746,2.397,,0.006,E,B,0.58,-1.21,0.978,,63.64,OHH,-1.04,0.520039,0.00936868,0.231593 beta-lactamase_2500_I140H,beta-lactamase_2500_140,TEM-1,beta-lactamase_2500,P62593,0.231603,NO,140,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.733,-4.991,3.258,,0.128,H,A,0.48,0.41,1.628,,73.08,PHO,-1.48733,0.361275,0.00597777,0.231603 kka2_1:4_F263C,kka2_1:4_263,Kka2,kka2_1:4,P00552,0.231661,NO,263,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-0.911,-4.889,3.978,,0.006,G,A,0.58,-0.12,2.284,,45.83,AHH,-0.92,0.168804,0.0172454,0.231661 kka2_1:1_E231H,kka2_1:1_231,Kka2,kka2_1:1,P00552,0.231695,NO,231,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.002,-4.353,2.351,,0.503,H,A,1.04,-0.23,25.629,25.629,63.26,AAH,-2.06267,0.520039,0.00732383,0.231695 kka2_1:4_K50H,kka2_1:4_50,Kka2,kka2_1:4,P00552,0.231697,NO,50,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-0.833,-4.481,3.648,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.168804,0.00138626,0.231697 kka2_1:2_D216T,kka2_1:2_216,Kka2,kka2_1:2,P00552,0.231756,NO,216,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.785,-3.493,2.708,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.295029,0.00229969,0.231756 kka2_1:8_I115H,kka2_1:8_115,Kka2,kka2_1:8,P00552,0.231771,NO,115,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.606,-5.024,3.418,,0.105,H,A,1.52,-1.18,4.064,,65.53,PHH,-2.205,0.100394,0.00836567,0.231771 kka2_1:8_I115H,kka2_1:8_115,Kka2,kka2_1:8,P00552,0.231771,NO,115,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.606,-5.024,3.418,,0.105,H,A,1.52,-1.18,4.064,,65.53,PHH,-2.205,0.100394,0.00836567,0.231771 kka2_1:4_H135P,kka2_1:4_135,Kka2,kka2_1:4,P00552,0.231792,NO,135,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-1.331,-3.963,2.632,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.168804,0.00532566,0.231792 kka2_1:2_R217I,kka2_1:2_217,Kka2,kka2_1:2,P00552,0.231803,NO,217,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.158,-2.477,1.319,,0.252,T,A,1.2,-0.59,0.381,,52.27,ABH,-1.127,0.295029,0.0047191,0.231803 beta-lactamase_625_M209Q,beta-lactamase_625_209,TEM-1,beta-lactamase_625,P62593,0.23183,NO,209,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.442,-3.974,2.532,,,H,A,0.55,-0.97,1.167,,64.69,HHA,-1.52633,0.213352,0.00625021,0.23183 beta-lactamase_625_A246F,beta-lactamase_625_246,TEM-1,beta-lactamase_625,P62593,0.231924,NO,246,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.121,-2.727,0.606,,0.01,E,B,0.46,-1.01,1.201,,73.78,HHH,-1.55633,0.213352,0.00569458,0.231924 kka2_1:8_F256D,kka2_1:8_256,Kka2,kka2_1:8,P00552,0.231941,NO,256,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.49,-4.089,2.599,,,H,A,1.62,-0.78,1.713,,53.03,HHH,-1.423,0.100394,0.0132841,0.231941 kka2_1:8_F256D,kka2_1:8_256,Kka2,kka2_1:8,P00552,0.231941,NO,256,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.49,-4.089,2.599,,,H,A,1.62,-0.78,1.713,,53.03,HHH,-1.423,0.100394,0.0132841,0.231941 kka2_1:2_L60C,kka2_1:2_60,Kka2,kka2_1:2,P00552,0.231997,NO,60,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.997,-4.773,3.776,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.295029,0.00262176,0.231997 kka2_1:2_F264K,kka2_1:2_264,Kka2,kka2_1:2,P00552,0.23202,NO,264,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.02,-3.94,2.92,,0.296,.,?,0.58,0.02,2.303,,71.59,HHNA,-0.9655,0.295029,,0.23202 beta-lactamase_39_C75H,beta-lactamase_39_75,TEM-1,beta-lactamase_39,P62593,0.232048,NO,75,C,H,CH,Special,PositiveCharge,5.07,7.59,2.52,174,121,155,34,108.5,153.2,44.7,-1.245,-4.871,3.626,,,H,A,0.46,-0.87,2.369,,50,HOO,-1.24333,0.0495842,0.0034616,0.232048 kka2_1:2_D90F,kka2_1:2_90,Kka2,kka2_1:2,P00552,0.23205,NO,90,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.459,-3.305,0.846,,0.104,E,B,0.75,0.73,6.085,,64.39,BAH,-1.72833,0.295029,0.00583842,0.23205 kka2_1:1_D90K,kka2_1:1_90,Kka2,kka2_1:1,P00552,0.232111,NO,90,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.459,-3.563,1.104,,0.104,E,B,0.75,0.73,6.085,,64.39,BAH,-1.72833,0.520039,0.00583842,0.232111 kka2_1:1_V16W,kka2_1:1_16,Kka2,kka2_1:1,P00552,0.232115,NO,16,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-3.087,-5.53,2.443,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.520039,0.00694011,0.232115 kka2_1:2_W236Y,kka2_1:2_236,Kka2,kka2_1:2,P00552,0.232176,NO,236,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-1.363,-2.865,1.502,,0.303,H,A,1.51,-0.76,5.58,,48.48,AHH,-1.81267,0.295029,0.0088796,0.232176 kka2_1:1_Q219V,kka2_1:1_219,Kka2,kka2_1:1,P00552,0.232188,NO,219,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-0.93,-3.601,2.671,,0.088,H,A,0.4,-0.85,1.917,,50,HPA,-1.05167,0.520039,0.00237913,0.232188 kka2_1:2_Y218T,kka2_1:2_218,Kka2,kka2_1:2,P00552,0.232217,NO,218,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-1.438,-3.77,2.332,,0.122,H,A,0.21,-0.69,1.022,,56.06,BHP,-1.17533,0.295029,0.0126098,0.232217 kka2_1:4_I196A,kka2_1:4_196,Kka2,kka2_1:4,P00552,0.232232,NO,196,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-2.115,-3.338,1.223,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.168804,0.0107273,0.232232 kka2_1:1_S104W,kka2_1:1_104,Kka2,kka2_1:1,P00552,0.232234,NO,104,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.436,-5.482,4.046,,0.536,T,A,0.27,-1.11,5.49,,63.64,HPP,-1.91433,0.520039,0.00555207,0.232234 kka2_1:2_C209I,kka2_1:2_209,Kka2,kka2_1:2,P00552,0.232272,NO,209,C,I,CI,Special,Hydrophobic,5.07,6.02,0.95,198,121,131,10,108.5,166.7,58.2,-0.906,-3.519,2.613,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.295029,0.00260862,0.232272 kka2_1:8_E230I,kka2_1:8_230,Kka2,kka2_1:8,P00552,0.232282,NO,230,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.672,-3.969,1.297,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.100394,0.00920051,0.232282 kka2_1:8_E230I,kka2_1:8_230,Kka2,kka2_1:8,P00552,0.232282,NO,230,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.672,-3.969,1.297,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.100394,0.00920051,0.232282 kka2_1:2_D261T,kka2_1:2_261,Kka2,kka2_1:2,P00552,0.232285,NO,261,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.708,-3.45,2.742,,0.146,G,A,0.75,-0.33,,,,HAA,-0.759333,0.295029,0.0224846,0.232285 kka2_1:1_D101C,kka2_1:1_101,Kka2,kka2_1:1,P00552,0.232368,NO,101,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.028,-5.093,4.065,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.520039,0.00423361,0.232368 kka2_1:1_E182R,kka2_1:1_182,Kka2,kka2_1:1,P00552,0.232441,NO,182,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.516,-3.801,2.285,,0.326,,B,1.52,0.75,14.547,14.547,65.53,OAA,-1.806,0.520039,0.00641548,0.232441 beta-lactamase_2500_L205K,beta-lactamase_2500_205,TEM-1,beta-lactamase_2500,P62593,0.232451,NO,205,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.922,-3.736,2.814,,,H,A,0.55,-0.46,0.831,,42.31,PHH,-1.57767,0.361275,0.00255802,0.232451 beta-lactamase_625_S57P,beta-lactamase_625_57,TEM-1,beta-lactamase_625,P62593,0.232478,NO,57,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.918,-3.952,2.034,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.213352,0.00492804,0.232478 kka2_1:1_W69F,kka2_1:1_69,Kka2,kka2_1:1,P00552,0.232492,NO,69,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-0.859,-3.388,2.529,,0.164,H,A,0.47,0.15,5.074,,38.64,PHH,-1.49967,0.520039,0.0012874,0.232492 kka2_1:1_W69V,kka2_1:1_69,Kka2,kka2_1:1,P00552,0.232492,NO,69,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-0.859,-3.749,2.89,,0.164,H,A,0.47,0.15,5.074,,38.64,PHH,-1.49967,0.520039,0.0012874,0.232492 beta-lactamase_625_N168P,beta-lactamase_625_168,TEM-1,beta-lactamase_625,P62593,0.232495,NO,168,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-1.029,-3.858,2.829,,0.113,G,A,0.61,-0.4,1.014,,44.41,HPA,-1.13233,0.213352,0.00288667,0.232495 kka2_1:1_E160W,kka2_1:1_160,Kka2,kka2_1:1,P00552,0.232502,NO,160,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.683,-5.621,3.938,,0.989,G,A,1.04,2.28,0.273,,71.59,AAA,-1.36133,0.520039,0.00935762,0.232502 beta-lactamase_2500_K286P,beta-lactamase_2500_286,TEM-1,beta-lactamase_2500,P62593,0.232511,NO,286,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.361275,,0.232511 beta-lactamase_2500_L248N,beta-lactamase_2500_248,TEM-1,beta-lactamase_2500,P62593,0.232552,NO,248,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.361275,0.00428493,0.232552 kka2_1:4_L70K,kka2_1:4_70,Kka2,kka2_1:4,P00552,0.232571,NO,70,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.017,-3.772,2.755,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.168804,0.00411884,0.232571 kka2_1:2_H162M,kka2_1:2_162,Kka2,kka2_1:2,P00552,0.232576,NO,162,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-2.319,-4.675,2.356,,0.071,G,A,0.17,1.01,3.187,,64.39,ABP,-2.02067,0.295029,0.00616145,0.232576 kka2_1:1_R44H,kka2_1:1_44,Kka2,kka2_1:1,P00552,0.232581,NO,44,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.062,-3.488,1.426,,0.487,S,B,1.2,-0.35,2.717,,71.59,OBO,-1.80767,0.520039,0.00745043,0.232581 kka2_1:8_A34F,kka2_1:8_34,Kka2,kka2_1:8,P00552,0.232622,NO,34,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.928,-4.127,3.199,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.100394,0.00343484,0.232622 kka2_1:8_A34F,kka2_1:8_34,Kka2,kka2_1:8,P00552,0.232622,NO,34,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.928,-4.127,3.199,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.100394,0.00343484,0.232622 kka2_1:8_S32H,kka2_1:8_32,Kka2,kka2_1:8,P00552,0.232622,NO,32,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-0.804,-4.483,3.679,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.100394,0.00149998,0.232622 kka2_1:8_S32H,kka2_1:8_32,Kka2,kka2_1:8,P00552,0.232622,NO,32,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-0.804,-4.483,3.679,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.100394,0.00149998,0.232622 kka2_1:8_S32M,kka2_1:8_32,Kka2,kka2_1:8,P00552,0.232622,NO,32,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-0.804,-4.508,3.704,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.100394,0.00149998,0.232622 kka2_1:8_S32M,kka2_1:8_32,Kka2,kka2_1:8,P00552,0.232622,NO,32,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-0.804,-4.508,3.704,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.100394,0.00149998,0.232622 beta-lactamase_156_V78D,beta-lactamase_156_78,TEM-1,beta-lactamase_156,P62593,0.232638,NO,78,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.459,-4.082,2.623,,,H,A,0.44,-0.47,1.132,,63.64,HHH,-1.17833,0.111618,0.00492501,0.232638 kka2_1:2_D190M,kka2_1:2_190,Kka2,kka2_1:2,P00552,0.232653,NO,190,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.708,-4.958,4.25,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.295029,0.00247989,0.232653 beta-lactamase_2500_L223W,beta-lactamase_2500_223,TEM-1,beta-lactamase_2500,P62593,0.232694,NO,223,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.055,-5.101,4.046,,0.27,,B,0.55,0.09,1.334,,74.48,HHO,-1.35033,0.361275,0.00372793,0.232694 kka2_1:4_R217D,kka2_1:4_217,Kka2,kka2_1:4,P00552,0.232725,NO,217,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.158,-3.819,2.661,,0.252,T,A,1.2,-0.59,2.074,,52.27,ABH,-1.127,0.168804,0.0047191,0.232725 kka2_1:4_A117M,kka2_1:4_117,Kka2,kka2_1:4,P00552,0.232734,NO,117,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.828,-4.464,3.636,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.168804,0.00282984,0.232734 beta-lactamase_625_T158M,beta-lactamase_625_158,TEM-1,beta-lactamase_625,P62593,0.232747,NO,158,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.116,-4.575,3.459,,0.036,,B,0.22,-0.85,3.771,,69.58,HPB,-1.269,0.213352,0.00341825,0.232747 PSD95pdz3_G329F,PSD95pdz3_329,PSD95pdz3,PSD95pdz3,P31016,0.232752,NO,329,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.008,-3.974,2.966,4.7671,,,,,19.7075,,,,HOO,-1.16033,0.0758425,0.000974577,0.232752 beta-lactamase_625_S241P,beta-lactamase_625_241,TEM-1,beta-lactamase_625,P62593,0.23276,NO,241,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.213352,0.00452736,0.23276 kka2_1:4_R217F,kka2_1:4_217,Kka2,kka2_1:4,P00552,0.232854,NO,217,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.158,-4.264,3.106,,0.252,T,A,1.2,-0.59,2.074,,52.27,ABH,-1.127,0.168804,0.0047191,0.232854 kka2_1:1_D220E,kka2_1:1_220,Kka2,kka2_1:1,P00552,0.232938,NO,220,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.787,-2.878,2.091,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.520039,0.00158066,0.232938 beta-lactamase_625_I229D,beta-lactamase_625_229,TEM-1,beta-lactamase_625,P62593,0.233006,NO,229,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.267,-3.973,2.706,,0.083,E,B,0.48,-0.76,1.69,,50,HHH,-1.58767,0.213352,0.00477249,0.233006 beta-lactamase_L146S,beta-lactamase_146,TEM-1,beta-lactamase,P62593,0.233043,NO,146,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.462,-2.916,1.454,5.62483,0.007,H,A,1.3,-0.56,1.953,,64.69,AHP,-1.656,0.221079,0.00474542,0.233043 beta-lactamase_2500_V78K,beta-lactamase_2500_78,TEM-1,beta-lactamase_2500,P62593,0.233121,NO,78,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.459,-3.849,2.39,,,H,A,0.44,-0.47,31.376,31.376,63.64,HHH,-1.17833,0.361275,0.00492501,0.233121 hsp90_S586D,hsp90_586,hsp90,hsp90,P02829,0.233154,NO,586,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.764,-2.847,0,4.65438,,,B,0.93,0.15,,,,HPH,-3.157,0.368192,0.000222939,0.233154 kka2_1:1_H188V,kka2_1:1_188,Kka2,kka2_1:1,P00552,0.233155,NO,188,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-0.913,-3.78,2.867,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.520039,0.00273139,0.233155 kka2_1:4_N195C,kka2_1:4_195,Kka2,kka2_1:4,P00552,0.233156,NO,195,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-0.836,-5.139,4.303,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.168804,0.00276134,0.233156 beta-lactamase_625_Y44C,beta-lactamase_625_44,TEM-1,beta-lactamase_625,P62593,0.233157,NO,44,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-2.547,-4.829,2.282,,,E,B,0.21,-0.45,2.371,,73.78,OHH,-1.86267,0.213352,0.00426364,0.233157 beta-lactamase_2500_P65M,beta-lactamase_2500_65,TEM-1,beta-lactamase_2500,P62593,0.233166,NO,65,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.894,-4.494,3.6,,0.098,E,B,0.52,-0.62,0.3,,40.56,HOH,-1.03233,0.361275,0.00152776,0.233166 beta-lactamase_625_I258W,beta-lactamase_625_258,TEM-1,beta-lactamase_625,P62593,0.233189,NO,258,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.213352,0.007931,0.233189 beta-lactamase_M184N,beta-lactamase_184,TEM-1,beta-lactamase,P62593,0.233247,NO,184,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.593,-4.028,2.435,5.39575,,H,A,1.3,-0.87,2.893,,62.94,HHH,-1.41,0.221079,0.00356019,0.233247 beta-lactamase_625_P143Y,beta-lactamase_625_143,TEM-1,beta-lactamase_625,P62593,0.233251,NO,143,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.967,-4.337,3.37,,0.075,H,A,0.52,-0.37,1.445,,66.78,OOB,-1.354,0.213352,0.00114551,0.233251 beta-lactamase_156_T179L,beta-lactamase_156_179,TEM-1,beta-lactamase_156,P62593,0.233254,NO,179,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.085,-3.263,2.178,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.111618,0.00226045,0.233254 beta-lactamase_156_P181W,beta-lactamase_156_181,TEM-1,beta-lactamase_156,P62593,0.233291,NO,181,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.813,-5.545,4.732,,,H,A,0.52,-1.14,1.078,,61.54,HOH,-1.795,0.111618,0.000703122,0.233291 beta-lactamase_2500_D174L,beta-lactamase_2500_174,TEM-1,beta-lactamase_2500,P62593,0.233358,NO,174,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.738,-3.808,3.07,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.361275,0.00125633,0.233358 kka2_1:4_R66Q,kka2_1:4_66,Kka2,kka2_1:4,P00552,0.233364,NO,66,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-0.922,-3.512,2.59,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.168804,0.00161025,0.233364 beta-lactamase_I229R,beta-lactamase_229,TEM-1,beta-lactamase,P62593,0.233372,NO,229,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.267,-4.174,2.907,5.0911,0.083,E,B,1,-0.76,1.114,,50,HHH,-1.58767,0.221079,0.00477249,0.233372 hsp90_W585H,hsp90_585,hsp90,hsp90,P02829,0.233392,NO,585,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-4.251,-3.833,0,5.31455,0.508,,B,1.22,0.43,,,,OHP,-3.17533,0.368192,0.000222939,0.233392 kka2_1:2_P12G,kka2_1:2_12,Kka2,kka2_1:2,P00552,0.233425,NO,12,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.853,-3.308,2.455,,,.,B,0.52,1.25,0.261,,48.11,POH,-1.80767,0.295029,0.00500011,0.233425 beta-lactamase_2500_L146T,beta-lactamase_2500_146,TEM-1,beta-lactamase_2500,P62593,0.233427,NO,146,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.462,-3.533,2.071,,0.007,H,A,0.55,-0.56,1.578,,64.69,AHP,-1.656,0.361275,0.00474542,0.233427 beta-lactamase_156_I244K,beta-lactamase_156_244,TEM-1,beta-lactamase_156,P62593,0.233496,NO,244,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.555,-3.812,2.257,,,E,B,0.48,-0.84,1.325,,77.62,OHH,-1.385,0.111618,0.00605379,0.233496 kka2_1:2_D220W,kka2_1:2_220,Kka2,kka2_1:2,P00552,0.233506,NO,220,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.787,-5.574,4.787,,,H,A,0.75,-1.14,0.745,,46.59,PAH,-1.152,0.295029,0.00158066,0.233506 kka2_1:1_V153N,kka2_1:1_153,Kka2,kka2_1:1,P00552,0.233519,NO,153,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.092,-4.209,3.117,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.520039,0.00501119,0.233519 beta-lactamase_S233Y,beta-lactamase_233,TEM-1,beta-lactamase,P62593,0.233649,NO,233,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.886,-4.293,2.407,4.98121,0.016,E,B,0.48,-1.01,5.361,,77.62,BPO,-1.17267,0.221079,0.00311415,0.233649 kka2_1:2_L93F,kka2_1:2_93,Kka2,kka2_1:2,P00552,0.233681,NO,93,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.815,-3.719,2.904,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.295029,0.00131498,0.233681 kka2_1:2_V97H,kka2_1:2_97,Kka2,kka2_1:2,P00552,0.233729,NO,97,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.453,-5.043,3.59,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.295029,0.00737869,0.233729 kka2_1:1_I196G,kka2_1:1_196,Kka2,kka2_1:1,P00552,0.233736,NO,196,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-2.115,-3.858,1.743,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.520039,0.0107273,0.233736 beta-lactamase_2500_S201D,beta-lactamase_2500_201,TEM-1,beta-lactamase_2500,P62593,0.233848,NO,201,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.183,-3.453,2.27,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.361275,0.00198815,0.233848 Ubiquitin_F45E,Ubiquitin_45,Uba1,Ubiquitin,P0CG48,0.233871,NO,45,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.322,-3.877,2.555,4.80693,0.26,E,B,1.62,-0.99,1.531,,53.87,HHH,-1.55267,0.205827,0.000470401,0.233871 Ubiquitin_G75P,Ubiquitin_75,Uba1,Ubiquitin,P0CG48,0.233871,NO,75,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.613,-4.034,2.421,5.44099,0.552,T,A,0.73,0.9,4.017,,34.31,BOO,-1.66767,0.205827,0.000712673,0.233871 Ubiquitin_K48A,Ubiquitin_48,Uba1,Ubiquitin,P0CG48,0.233871,NO,48,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.436,-3.131,1.695,5.03072,0.132,E,B,2.92,-0.28,1.539,,53.87,OBP,-1.6,0.205827,0.000394633,0.233871 Ubiquitin_K48Q,Ubiquitin_48,Uba1,Ubiquitin,P0CG48,0.233871,NO,48,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.436,-3.59,2.154,5.03072,0.132,E,B,2.92,-0.28,1.539,,53.87,OBP,-1.6,0.205827,0.000394633,0.233871 Ubiquitin_L43R,Ubiquitin_43,Uba1,Ubiquitin,P0CG48,0.233871,NO,43,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.269,-2.878,1.609,4.8799,,E,B,1.75,-1.17,10.246,10.246,53.87,BHH,-1.46867,0.205827,0.000572481,0.233871 Ubiquitin_L73A,Ubiquitin_73,Uba1,Ubiquitin,P0CG48,0.233871,NO,73,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.801,-2.46,0.659,5.27116,0.518,,B,0.77,1,10.519,10.519,34.31,BHB,-1.858,0.205827,0.000710624,0.233871 Ubiquitin_L8C,Ubiquitin_8,Uba1,Ubiquitin,P0CG48,0.233871,NO,8,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.723,-4.911,3.188,5.28016,0.664,T,A,0.08,-0.34,0.664,,29.05,PHP,-1.51567,0.205827,0.000726165,0.233871 Ubiquitin_Q31P,Ubiquitin_31,Uba1,Ubiquitin,P0CG48,0.233871,NO,31,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-1.678,-3.88,2.202,4.5004,0.464,H,A,,0.68,,,,HPA,-1.44467,0.205827,0.000724141,0.233871 Ubiquitin_T7D,Ubiquitin_7,Uba1,Ubiquitin,P0CG48,0.233871,NO,7,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.415,-3.568,2.153,4.954,0.094,E,B,0.43,-0.78,0.805,,21.31,BPH,-1.41033,0.205827,0.000647855,0.233871 kka2_1:2_T187G,kka2_1:2_187,Kka2,kka2_1:2,P00552,0.233882,NO,187,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.273,-3.394,2.121,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.295029,0.00693073,0.233882 kka2_1:4_V198Y,kka2_1:4_198,Kka2,kka2_1:4,P00552,0.233882,NO,198,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.719,-4.264,2.545,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.168804,0.00835002,0.233882 beta-lactamase_625_E46P,beta-lactamase_625_46,TEM-1,beta-lactamase_625,P62593,0.233888,NO,46,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.94,-4.039,2.099,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.213352,0.00427568,0.233888 kka2_1:2_D159C,kka2_1:2_159,Kka2,kka2_1:2,P00552,0.233904,NO,159,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.82,-5.15,4.33,,0.28,.,B,0.75,1.25,0.899,,48.11,HAA,-1.48333,0.295029,0.0030485,0.233904 kka2_1:2_V36F,kka2_1:2_36,Kka2,kka2_1:2,P00552,0.23394,NO,36,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-0.898,-3.87,2.972,,0.292,E,B,1.48,0.21,1.064,,52.27,HHH,-1.484,0.295029,0.00245633,0.23394 kka2_1:1_D208V,kka2_1:1_208,Kka2,kka2_1:1,P00552,0.233962,NO,208,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.708,-3.782,3.074,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.520039,0.00212588,0.233962 kka2_1:4_L57E,kka2_1:4_57,Kka2,kka2_1:4,P00552,0.234009,NO,57,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.898,-3.855,1.957,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.168804,0.00723769,0.234009 kka2_1:4_D216H,kka2_1:4_216,Kka2,kka2_1:4,P00552,0.234051,NO,216,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.785,-2.903,2.118,,0.018,E,B,0.75,-0.51,0.112,,19.32,HAB,-0.970333,0.168804,0.00229969,0.234051 beta-lactamase_625_I280R,beta-lactamase_625_280,TEM-1,beta-lactamase_625,P62593,0.234063,NO,280,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.213352,0.0530888,0.234063 kka2_1:1_I254K,kka2_1:1_254,Kka2,kka2_1:1,P00552,0.234083,NO,254,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.933,-3.795,1.862,,0.135,H,A,1.52,-0.6,1.859,,71.59,BHH,-1.668,0.520039,0.0132375,0.234083 beta-lactamase_156_N130K,beta-lactamase_156_130,TEM-1,beta-lactamase_156,P62593,0.234115,NO,130,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-0.798,-3.232,2.434,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.111618,0.000683376,0.234115 kka2_1:4_I221G,kka2_1:4_221,Kka2,kka2_1:4,P00552,0.234115,NO,221,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.739,-3.884,2.145,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.168804,0.00945908,0.234115 beta-lactamase_2500_W227R,beta-lactamase_2500_227,TEM-1,beta-lactamase_2500,P62593,0.234162,NO,227,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-0.982,-4.182,3.2,,0.272,,B,0.47,-0.29,1.37,,74.48,OHH,-1.595,0.361275,0.00226019,0.234162 kka2_1:2_D156K,kka2_1:2_156,Kka2,kka2_1:2,P00552,0.23417,NO,156,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.696,-3.566,1.87,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.295029,0.00926998,0.23417 kka2_1:1_D261A,kka2_1:1_261,Kka2,kka2_1:1,P00552,0.234297,NO,261,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.708,-3.331,2.623,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.520039,0.0224846,0.234297 kka2_1:2_L259K,kka2_1:2_259,Kka2,kka2_1:2,P00552,0.234299,NO,259,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.088,-3.716,2.628,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.295029,0.0206964,0.234299 beta-lactamase_625_I125G,beta-lactamase_625_125,TEM-1,beta-lactamase_625,P62593,0.234302,NO,125,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.441,-3.768,2.327,,,H,A,0.48,-0.7,2.034,,63.29,HHP,-1.248,0.213352,0.00383964,0.234302 kka2_1:8_Y257R,kka2_1:8_257,Kka2,kka2_1:8,P00552,0.234319,NO,257,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-1.064,-4.088,3.024,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.100394,0.0148191,0.234319 kka2_1:8_Y257R,kka2_1:8_257,Kka2,kka2_1:8,P00552,0.234319,NO,257,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-1.064,-4.088,3.024,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.100394,0.0148191,0.234319 kka2_1:1_H135C,kka2_1:1_135,Kka2,kka2_1:1,P00552,0.23434,NO,135,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-1.331,-5.106,3.775,,0.071,.,a,0.17,0.65,3.574,,53.03,ABP,-1.77367,0.520039,0.00532566,0.23434 beta-lactamase_625_I140P,beta-lactamase_625_140,TEM-1,beta-lactamase_625,P62593,0.234388,NO,140,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.733,-4.152,2.419,,0.128,H,A,0.48,0.41,1.628,,73.08,PHO,-1.48733,0.213352,0.00597777,0.234388 beta-lactamase_625_S128A,beta-lactamase_625_128,TEM-1,beta-lactamase_625,P62593,0.234409,NO,128,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-0.84,-2.628,1.788,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.213352,0.00071483,0.234409 kka2_1:1_R253T,kka2_1:1_253,Kka2,kka2_1:1,P00552,0.234416,NO,253,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.356,-3.535,2.179,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.520039,0.0144195,0.234416 kka2_1:2_V186W,kka2_1:2_186,Kka2,kka2_1:2,P00552,0.234458,NO,186,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.011,-5.309,4.298,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.295029,0.00409703,0.234458 kka2_1:1_V214S,kka2_1:1_214,Kka2,kka2_1:1,P00552,0.234472,NO,214,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.261,-3.744,2.483,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.520039,0.00692782,0.234472 kka2_1:8_C77E,kka2_1:8_77,Kka2,kka2_1:8,P00552,0.234488,NO,77,C,E,CE,Special,negativeCharge,5.07,3.22,-1.85,170,121,147,26,108.5,138.4,29.9,-1.477,-3.891,2.414,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.100394,0.00441216,0.234488 kka2_1:8_C77E,kka2_1:8_77,Kka2,kka2_1:8,P00552,0.234488,NO,77,C,E,CE,Special,negativeCharge,5.07,3.22,-1.85,170,121,147,26,108.5,138.4,29.9,-1.477,-3.891,2.414,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.100394,0.00441216,0.234488 kka2_1:4_D261A,kka2_1:4_261,Kka2,kka2_1:4,P00552,0.234582,NO,261,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.708,-3.331,2.623,,0.146,G,A,0.75,-0.33,,,,HAA,-0.759333,0.168804,0.0224846,0.234582 kka2_1:1_C192A,kka2_1:1_192,Kka2,kka2_1:1,P00552,0.234607,NO,192,C,A,CA,Special,Hydrophobic,5.07,6,0.93,195,121,89,-32,108.5,88.6,-19.9,-1.067,-2.954,1.887,,0.095,.,B,0.46,-0.75,2.749,,50,HOH,-0.960333,0.520039,0.00485428,0.234607 beta-lactamase_625_H287P,beta-lactamase_625_287,TEM-1,beta-lactamase_625,P62593,0.234634,NO,287,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,,,,,,,,,,,,,BBH,-1.111,0.213352,,0.234634 beta-lactamase_625_K232W,beta-lactamase_625_232,TEM-1,beta-lactamase_625,P62593,0.234647,NO,232,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.012,-5.365,4.353,,,E,B,2.34,-1.1,1.992,,65.03,ABP,-1.238,0.213352,0.00313441,0.234647 kka2_1:8_W69V,kka2_1:8_69,Kka2,kka2_1:8,P00552,0.234657,NO,69,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-0.859,-3.749,2.89,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.100394,0.0012874,0.234657 kka2_1:8_W69V,kka2_1:8_69,Kka2,kka2_1:8,P00552,0.234657,NO,69,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-0.859,-3.749,2.89,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.100394,0.0012874,0.234657 beta-lactamase_156_N168P,beta-lactamase_156_168,TEM-1,beta-lactamase_156,P62593,0.23468,NO,168,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-1.029,-3.858,2.829,,0.113,G,A,0.61,-0.4,1.014,,44.41,HPA,-1.13233,0.111618,0.00288667,0.23468 beta-lactamase_2500_L219N,beta-lactamase_2500_219,TEM-1,beta-lactamase_2500,P62593,0.234721,NO,219,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.313,-4.217,2.904,,,I,A,0.55,-0.51,35.994,35.994,74.48,HHB,-1.21533,0.361275,0.00664345,0.234721 kka2_1:1_D250L,kka2_1:1_250,Kka2,kka2_1:1,P00552,0.23474,NO,250,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.015,-3.81,2.795,,0.274,.,b,0.75,-0.46,4.177,,51.89,OAP,-1.83933,0.520039,0.0177103,0.23474 beta-lactamase_2500_N274L,beta-lactamase_2500_274,TEM-1,beta-lactamase_2500,P62593,0.234742,NO,274,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.361275,0.0110418,0.234742 beta-lactamase_2500_L167G,beta-lactamase_2500_167,TEM-1,beta-lactamase_2500,P62593,0.234794,NO,167,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.138,-3.694,2.556,,0.015,G,A,0.55,-0.63,7.813,,64.69,AHP,-1.30767,0.361275,0.00303566,0.234794 beta-lactamase_625_L167P,beta-lactamase_625_167,TEM-1,beta-lactamase_625,P62593,0.234881,NO,167,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.138,-4.076,2.938,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.213352,0.00303566,0.234881 kka2_1:2_G233K,kka2_1:2_233,Kka2,kka2_1:2,P00552,0.234895,NO,233,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.748,-3.71,2.962,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.295029,0.00232366,0.234895 kka2_1:1_L70K,kka2_1:1_70,Kka2,kka2_1:1,P00552,0.234913,NO,70,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.017,-3.772,2.755,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.520039,0.00411884,0.234913 beta-lactamase_2500_T193P,beta-lactamase_2500_193,TEM-1,beta-lactamase_2500,P62593,0.234931,NO,193,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.914,-4.072,2.158,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.361275,0.00482669,0.234931 beta-lactamase_C121E,beta-lactamase_121,TEM-1,beta-lactamase,P62593,0.23498,NO,121,C,E,CE,Special,negativeCharge,5.07,3.22,-1.85,170,121,147,26,108.5,138.4,29.9,-0.953,-3.987,3.034,5.12205,,H,A,2.8,-0.81,7.644,,63.29,HOP,-1.46767,0.221079,0.000744322,0.23498 kka2_1:1_R44C,kka2_1:1_44,Kka2,kka2_1:1,P00552,0.235007,NO,44,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.062,-5.189,3.127,,0.487,S,B,1.2,-0.35,2.717,,71.59,OBO,-1.80767,0.520039,0.00745043,0.235007 kka2_1:2_E169P,kka2_1:2_169,Kka2,kka2_1:2,P00552,0.235058,NO,169,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.996,-4.008,2.012,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.295029,0.00730086,0.235058 PSD95pdz3_L323P,PSD95pdz3_323,PSD95pdz3,PSD95pdz3,P31016,0.235058,NO,323,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.347,-3.786,2.439,5.12397,,,,,13.8825,,,,OHO,-1.121,0.0758425,0.00104644,0.235058 beta-lactamase_156_E61P,beta-lactamase_156_61,TEM-1,beta-lactamase_156,P62593,0.235071,NO,61,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.115,-3.861,1.746,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.111618,0.00440955,0.235071 kka2_1:1_W91M,kka2_1:1_91,Kka2,kka2_1:1,P00552,0.235075,NO,91,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-1.178,-4.551,3.373,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.520039,0.00358653,0.235075 beta-lactamase_2500_I261K,beta-lactamase_2500_261,TEM-1,beta-lactamase_2500,P62593,0.235116,NO,261,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.361275,0.0123091,0.235116 beta-lactamase_625_I280E,beta-lactamase_625_280,TEM-1,beta-lactamase_625,P62593,0.23512,NO,280,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.213352,0.0530888,0.23512 beta-lactamase_2500_R220M,beta-lactamase_2500_220,TEM-1,beta-lactamase_2500,P62593,0.235202,NO,220,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-0.942,-4.506,3.564,,0.295,I,A,1.2,-0.76,2.175,,74.48,HBP,-1.33633,0.361275,0.00232421,0.235202 kka2_1:1_T28K,kka2_1:1_28,Kka2,kka2_1:1,P00552,0.235225,NO,28,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.883,-3.68,1.797,,0.353,S,B,0.22,2.02,1.12,,63.64,PPH,-1.74467,0.520039,0.00743084,0.235225 beta-lactamase_2500_W288N,beta-lactamase_2500_288,TEM-1,beta-lactamase_2500,P62593,0.235251,NO,288,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,,,,,,,,,,,,,BHO,,0.361275,,0.235251 beta-lactamase_2500_K232Q,beta-lactamase_2500_232,TEM-1,beta-lactamase_2500,P62593,0.235278,NO,232,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.012,-3.492,2.48,,,E,B,2.34,-1.1,3.048,,65.03,ABP,-1.238,0.361275,0.00313441,0.235278 kka2_1:2_G213L,kka2_1:2_213,Kka2,kka2_1:2,P00552,0.2353,NO,213,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.596,-3.836,3.24,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.295029,0.00187654,0.2353 beta-lactamase_625_T69F,beta-lactamase_625_69,TEM-1,beta-lactamase_625,P62593,0.235314,NO,69,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-0.973,-4.127,3.154,,,G,A,0.22,-1.24,2.716,,93.01,PPH,-1.01833,0.213352,0.00127498,0.235314 kka2_1:8_I228N,kka2_1:8_228,Kka2,kka2_1:8,P00552,0.235333,NO,228,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.142,-4.223,3.081,,,H,A,1.52,-1.2,1.521,,71.59,AHH,-1.54633,0.100394,0.00458834,0.235333 kka2_1:8_I228N,kka2_1:8_228,Kka2,kka2_1:8,P00552,0.235333,NO,228,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.142,-4.223,3.081,,,H,A,1.52,-1.2,1.521,,71.59,AHH,-1.54633,0.100394,0.00458834,0.235333 kka2_1:1_G201A,kka2_1:1_201,Kka2,kka2_1:1,P00552,0.235361,NO,201,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.56,-3.247,1.687,,0.149,T,l,0.29,-0.57,16.092,16.092,52.65,POB,-1.92233,0.520039,0.00820117,0.235361 kka2_1:2_I196P,kka2_1:2_196,Kka2,kka2_1:2,P00552,0.235376,NO,196,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-2.115,-4.338,2.223,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.295029,0.0107273,0.235376 beta-lactamase_2500_V72F,beta-lactamase_2500_72,TEM-1,beta-lactamase_2500,P62593,0.23539,NO,72,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.658,-3.023,1.365,,,H,A,0.44,-1.03,2.079,,65.73,BHH,-1.32167,0.361275,0.00501194,0.23539 kka2_1:1_G213M,kka2_1:1_213,Kka2,kka2_1:1,P00552,0.235409,NO,213,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.596,-4.958,4.362,,,E,b,0.29,-0.4,,,,HOH,-0.920333,0.520039,0.00187654,0.235409 kka2_1:2_A237C,kka2_1:2_237,Kka2,kka2_1:2,P00552,0.235419,NO,237,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.12,-4.796,2.676,,0.068,H,A,0.46,-0.71,2.369,,92.05,HHA,-2.10433,0.295029,0.012257,0.235419 beta-lactamase_2500_G240H,beta-lactamase_2500_240,TEM-1,beta-lactamase_2500,P62593,0.235423,NO,240,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.361275,0.00591201,0.235423 beta-lactamase_625_D129I,beta-lactamase_625_129,TEM-1,beta-lactamase_625,P62593,0.235495,NO,129,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.816,-4.036,3.22,,,,B,0.75,-0.69,0.171,,34.97,PAP,-0.818,0.213352,0.00109178,0.235495 kka2_1:4_V153N,kka2_1:4_153,Kka2,kka2_1:4,P00552,0.235496,NO,153,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.092,-4.209,3.117,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.168804,0.00501119,0.235496 beta-lactamase_2500_S233I,beta-lactamase_2500_233,TEM-1,beta-lactamase_2500,P62593,0.235498,NO,233,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.886,-3.784,1.898,,0.016,E,B,0.27,-1.01,2.851,,77.62,BPO,-1.17267,0.361275,0.00311415,0.235498 kka2_1:8_Y218R,kka2_1:8_218,Kka2,kka2_1:8,P00552,0.235501,NO,218,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-1.438,-3.984,2.546,,0.122,H,A,1.25,-0.69,2.923,,56.06,BHP,-1.17533,0.100394,0.0126098,0.235501 kka2_1:8_Y218R,kka2_1:8_218,Kka2,kka2_1:8,P00552,0.235501,NO,218,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-1.438,-3.984,2.546,,0.122,H,A,1.25,-0.69,2.923,,56.06,BHP,-1.17533,0.100394,0.0126098,0.235501 kka2_1:1_T72E,kka2_1:1_72,Kka2,kka2_1:1,P00552,0.235555,NO,72,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.38,-2.356,-0.024,,0.784,H,A,0.22,0.29,10.43,10.43,65.53,HPP,-2.238,0.520039,0.00750756,0.235555 beta-lactamase_39_K232I,beta-lactamase_39_232,TEM-1,beta-lactamase_39,P62593,0.235601,NO,232,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.012,-4.053,3.041,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.0495842,0.00313441,0.235601 kka2_1:4_A222K,kka2_1:4_222,Kka2,kka2_1:4,P00552,0.235611,NO,222,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.725,-3.485,2.76,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.168804,0.00207657,0.235611 PSD95pdz3_E331P,PSD95pdz3_331,PSD95pdz3,PSD95pdz3,P31016,0.235619,NO,331,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.404,-3.336,1.932,5.86289,,,,,51.8889,,,,OAA,-1.22533,0.0758425,0.000950134,0.235619 kka2_1:1_R258W,kka2_1:1_258,Kka2,kka2_1:1,P00552,0.235653,NO,258,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.626,-5.364,3.738,,0.316,H,A,1.2,-0.85,7.485,7.485,53.03,HBH,-1.25933,0.520039,0.00983174,0.235653 kka2_1:2_F48K,kka2_1:2_48,Kka2,kka2_1:2,P00552,0.235732,NO,48,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.453,-3.972,2.519,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.295029,0.00475422,0.235732 beta-lactamase_625_T69N,beta-lactamase_625_69,TEM-1,beta-lactamase_625,P62593,0.235752,NO,69,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-0.973,-3.537,2.564,,,G,A,0.22,-1.24,2.716,,93.01,PPH,-1.01833,0.213352,0.00127498,0.235752 kka2_1:1_A176M,kka2_1:1_176,Kka2,kka2_1:1,P00552,0.235925,NO,176,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.621,-4.76,3.139,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.520039,0.0083587,0.235925 kka2_1:2_D250T,kka2_1:2_250,Kka2,kka2_1:2,P00552,0.235953,NO,250,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.015,-3.493,2.478,,0.274,.,b,0.75,-0.46,3.796,,51.89,OAP,-1.83933,0.295029,0.0177103,0.235953 beta-lactamase_39_Y262D,beta-lactamase_39_262,TEM-1,beta-lactamase_39,P62593,0.235968,NO,262,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.0495842,0.00853516,0.235968 kka2_1:1_V113I,kka2_1:1_113,Kka2,kka2_1:1,P00552,0.235968,NO,113,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.233,-1.634,0.401,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.520039,0.00650191,0.235968 kka2_1:4_F264K,kka2_1:4_264,Kka2,kka2_1:4,P00552,0.23598,NO,264,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.02,-3.94,2.92,,0.296,,?,1.62,0.02,1.93,,71.59,HHO,-0.9655,0.168804,,0.23598 kka2_1:1_A137G,kka2_1:1_137,Kka2,kka2_1:1,P00552,0.235991,NO,137,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.156,-3.64,1.484,,0.029,H,A,0.46,0.34,1.323,,63.26,PHB,-2.559,0.520039,0.00515054,0.235991 beta-lactamase_625_T178E,beta-lactamase_625_178,TEM-1,beta-lactamase_625,P62593,0.236031,NO,178,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-0.791,-3.44,2.649,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.213352,0.000684366,0.236031 kka2_1:2_Y257V,kka2_1:2_257,Kka2,kka2_1:2,P00552,0.236088,NO,257,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-1.064,-3.391,2.327,,0.022,H,A,0.21,-0.88,0.833,,52.65,HHB,-1.39333,0.295029,0.0148191,0.236088 kka2_1:1_A222W,kka2_1:1_222,Kka2,kka2_1:1,P00552,0.236107,NO,222,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.725,-5.351,4.626,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.520039,0.00207657,0.236107 kka2_1:1_Y218I,kka2_1:1_218,Kka2,kka2_1:1,P00552,0.236148,NO,218,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-1.438,-3.85,2.412,,0.122,H,A,1.25,-0.69,3.059,,56.06,BHP,-1.17533,0.520039,0.0126098,0.236148 kka2_1:8_D208C,kka2_1:8_208,Kka2,kka2_1:8,P00552,0.236175,NO,208,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.708,-5.115,4.407,,0.36,,l,0.29,-1.01,,,,HAO,-0.929667,0.100394,0.00212588,0.236175 kka2_1:8_D208C,kka2_1:8_208,Kka2,kka2_1:8,P00552,0.236175,NO,208,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.708,-5.115,4.407,,0.36,,l,0.29,-1.01,,,,HAO,-0.929667,0.100394,0.00212588,0.236175 kka2_1:8_I207R,kka2_1:8_207,Kka2,kka2_1:8,P00552,0.236175,NO,207,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.175,-4.245,3.07,,0.293,,B,1.52,-1.12,1.306,,56.06,HHA,-1.07733,0.100394,0.00611824,0.236175 kka2_1:8_I207R,kka2_1:8_207,Kka2,kka2_1:8,P00552,0.236175,NO,207,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.175,-4.245,3.07,,0.293,,B,1.52,-1.12,1.306,,56.06,HHA,-1.07733,0.100394,0.00611824,0.236175 kka2_1:8_M197W,kka2_1:8_197,Kka2,kka2_1:8,P00552,0.236175,NO,197,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.707,-5.268,3.561,,0.121,E,B,1.59,-1.19,4.408,,65.53,HHH,-1.847,0.100394,0.00921295,0.236175 kka2_1:8_M197W,kka2_1:8_197,Kka2,kka2_1:8,P00552,0.236175,NO,197,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.707,-5.268,3.561,,0.121,E,B,1.59,-1.19,4.408,,65.53,HHH,-1.847,0.100394,0.00921295,0.236175 beta-lactamase_156_K232C,beta-lactamase_156_232,TEM-1,beta-lactamase_156,P62593,0.236179,NO,232,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.012,-5.13,4.118,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.111618,0.00313441,0.236179 beta-lactamase_625_P143W,beta-lactamase_625_143,TEM-1,beta-lactamase_625,P62593,0.236204,NO,143,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.967,-5.497,4.53,,0.075,H,A,0.52,-0.37,1.445,,66.78,OOB,-1.354,0.213352,0.00114551,0.236204 beta-lactamase_156_C75E,beta-lactamase_156_75,TEM-1,beta-lactamase_156,P62593,0.236209,NO,75,C,E,CE,Special,negativeCharge,5.07,3.22,-1.85,170,121,147,26,108.5,138.4,29.9,-1.245,-3.874,2.629,,,H,A,0.46,-0.87,0.876,,50,HOO,-1.24333,0.111618,0.0034616,0.236209 kka2_1:4_G210F,kka2_1:4_210,Kka2,kka2_1:4,P00552,0.236297,NO,210,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.095,-4.324,3.229,,0.103,T,A,0.29,-0.62,0.271,,50,OOB,-0.966667,0.168804,0.00598378,0.236297 beta-lactamase_F64H,beta-lactamase_64,TEM-1,beta-lactamase,P62593,0.236301,NO,64,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-0.841,-4.455,3.614,5.70769,0.006,E,B,1.33,-0.95,,,,BHO,-0.892667,0.221079,0.000947691,0.236301 beta-lactamase_L74K,beta-lactamase_74,TEM-1,beta-lactamase,P62593,0.236301,NO,74,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.296,-3.688,2.392,5.50288,,H,A,1.75,-0.91,1.581,,50,HHO,-1.34933,0.221079,0.00493255,0.236301 kka2_1:1_L174D,kka2_1:1_174,Kka2,kka2_1:1,P00552,0.236301,NO,174,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.952,-4.154,3.202,,,H,A,0.55,-0.31,13.276,13.276,51.89,BHB,-2.08533,0.520039,0.00438501,0.236301 beta-lactamase_2500_L73R,beta-lactamase_2500_73,TEM-1,beta-lactamase_2500,P62593,0.236305,NO,73,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.507,-4.144,2.637,,,H,A,0.55,-0.64,2.178,,67.83,HHH,-1.487,0.361275,0.00488983,0.236305 kka2_1:1_Q136L,kka2_1:1_136,Kka2,kka2_1:1,P00552,0.236333,NO,136,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-3.021,-3.571,0.55,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.520039,0.00624149,0.236333 kka2_1:4_V49W,kka2_1:4_49,Kka2,kka2_1:4,P00552,0.236333,NO,49,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.614,-5.38,3.766,,,E,B,0.44,-0.77,1.233,,64.39,HHB,-1.3,0.168804,0.00615685,0.236333 kka2_1:8_A117W,kka2_1:8_117,Kka2,kka2_1:8,P00552,0.236343,NO,117,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.828,-5.385,4.557,,,H,A,1.04,-0.78,0.755,,45.83,HHA,-1.79333,0.100394,0.00282984,0.236343 kka2_1:8_A117W,kka2_1:8_117,Kka2,kka2_1:8,P00552,0.236343,NO,117,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.828,-5.385,4.557,,,H,A,1.04,-0.78,0.755,,45.83,HHA,-1.79333,0.100394,0.00282984,0.236343 kka2_1:4_D190P,kka2_1:4_190,Kka2,kka2_1:4,P00552,0.236353,NO,190,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.708,-3.683,2.975,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.168804,0.00247989,0.236353 kka2_1:1_P132D,kka2_1:1_132,Kka2,kka2_1:1,P00552,0.236354,NO,132,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.775,-3.495,2.72,,0.692,.,A,0.52,0.56,0.224,,44.7,OOH,-0.825667,0.520039,0.0018489,0.236354 beta-lactamase_156_G281R,beta-lactamase_156_281,TEM-1,beta-lactamase_156,P62593,0.236418,NO,281,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.111618,0.0406482,0.236418 kka2_1:1_N200F,kka2_1:1_200,Kka2,kka2_1:1,P00552,0.236436,NO,200,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-2.446,-4.524,2.078,,0.756,T,L,0.61,-0.08,17.299,17.299,64.39,APO,-2.08,0.520039,0.00838549,0.236436 kka2_1:2_F263K,kka2_1:2_263,Kka2,kka2_1:2,P00552,0.236469,NO,263,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-0.911,-3.934,3.023,,0.006,G,A,1.62,-0.12,5.275,,45.83,AHH,-0.92,0.295029,0.0172454,0.236469 beta-lactamase_156_A124P,beta-lactamase_156_124,TEM-1,beta-lactamase_156,P62593,0.236488,NO,124,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.181,-3.759,2.578,,,H,A,0.46,-0.9,2.027,,64.34,HHH,-1.152,0.111618,0.00481399,0.236488 hsp90_S586R,hsp90_586,hsp90,hsp90,P02829,0.236494,NO,586,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.764,-3.086,0,4.65438,,,B,0.93,0.15,,,,HPH,-3.157,0.368192,0.000222939,0.236494 kka2_1:1_S104N,kka2_1:1_104,Kka2,kka2_1:1,P00552,0.236498,NO,104,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.436,-2.903,1.467,,0.536,T,A,0.27,-1.11,5.49,,63.64,HPP,-1.91433,0.520039,0.00555207,0.236498 beta-lactamase_156_E210P,beta-lactamase_156_210,TEM-1,beta-lactamase_156,P62593,0.236511,NO,210,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.319,-4.023,1.704,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.111618,0.00663582,0.236511 kka2_1:4_E59Y,kka2_1:4_59,Kka2,kka2_1:4,P00552,0.236545,NO,59,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-0.952,-4.251,3.299,,0.187,.,L,1.04,0.62,3.408,,50.38,PAH,-1.53,0.168804,0.00280355,0.236545 kka2_1:1_I246P,kka2_1:1_246,Kka2,kka2_1:1,P00552,0.236554,NO,246,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-2.008,-3.255,1.247,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.520039,0.0139479,0.236554 beta-lactamase_2500_M184T,beta-lactamase_2500_184,TEM-1,beta-lactamase_2500,P62593,0.236582,NO,184,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.593,-2.764,1.171,,,H,A,0.55,-0.87,2.893,,62.94,HHH,-1.41,0.361275,0.00356019,0.236582 kka2_1:1_L232H,kka2_1:1_232,Kka2,kka2_1:1,P00552,0.236587,NO,232,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.514,-3.411,1.897,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.520039,0.00800103,0.236587 kka2_1:1_N58E,kka2_1:1_58,Kka2,kka2_1:1,P00552,0.236592,NO,58,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-2.641,-3.612,0.971,,0.131,S,A,0.61,0.72,30.755,30.755,71.59,HPA,-1.83033,0.520039,0.00793425,0.236592 kka2_1:2_L170K,kka2_1:2_170,Kka2,kka2_1:2,P00552,0.236605,NO,170,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.28,-3.796,2.516,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.295029,0.00730791,0.236605 kka2_1:1_A129D,kka2_1:1_129,Kka2,kka2_1:1,P00552,0.236623,NO,129,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.656,-2.499,0.843,,0.845,G,A,0.46,0.72,19.686,19.686,92.05,OHP,-1.99,0.520039,0.00726862,0.236623 kka2_1:4_G201W,kka2_1:4_201,Kka2,kka2_1:4,P00552,0.236751,NO,201,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.56,-5.537,3.977,,0.149,T,l,0.29,-0.57,0.284,,52.65,POB,-1.92233,0.168804,0.00820117,0.236751 kka2_1:2_A215Q,kka2_1:2_215,Kka2,kka2_1:2,P00552,0.236824,NO,215,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.968,-3.954,2.986,,0.039,E,B,0.46,-0.59,2.137,,50.38,HHA,-1.00467,0.295029,0.00529129,0.236824 kka2_1:2_D208L,kka2_1:2_208,Kka2,kka2_1:2,P00552,0.236828,NO,208,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.708,-3.836,3.128,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.295029,0.00212588,0.236828 kka2_1:1_M116G,kka2_1:1_116,Kka2,kka2_1:1,P00552,0.236856,NO,116,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-2.482,-3.754,1.272,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.520039,0.00745147,0.236856 kka2_1:1_A255M,kka2_1:1_255,Kka2,kka2_1:1,P00552,0.236866,NO,255,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.715,-4.815,3.1,,0.466,H,A,0.46,-0.52,0.946,,65.53,HHH,-1.71267,0.520039,0.0126809,0.236866 beta-lactamase_625_M127P,beta-lactamase_625_127,TEM-1,beta-lactamase_625,P62593,0.236891,NO,127,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-2.251,-4.144,1.893,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.213352,0.00437927,0.236891 kka2_1:1_L241C,kka2_1:1_241,Kka2,kka2_1:1,P00552,0.236984,NO,241,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.158,-3.073,1.915,,0.08,H,A,0.55,-0.82,1.685,,63.26,HHH,-1.58533,0.520039,0.0117299,0.236984 beta-lactamase_625_W208R,beta-lactamase_625_208,TEM-1,beta-lactamase_625,P62593,0.237088,NO,208,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-0.818,-4.158,3.34,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.213352,0.00126609,0.237088 kka2_1:1_Q42Y,kka2_1:1_42,Kka2,kka2_1:1,P00552,0.237132,NO,42,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.907,-4.454,1.547,,1.044,T,B,0.4,-0.8,2.792,,71.59,HPO,-2.12433,0.520039,0.00679212,0.237132 kka2_1:1_G43F,kka2_1:1_43,Kka2,kka2_1:1,P00552,0.237157,NO,43,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.587,-4.379,2.792,,0.862,T,l,0.75,-0.67,2.247,,63.26,POB,-2.18533,0.520039,0.0071925,0.237157 kka2_1:1_L223Y,kka2_1:1_223,Kka2,kka2_1:1,P00552,0.237201,NO,223,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.861,-4.01,3.149,,,H,A,0.55,-1.24,1.268,,50,HHH,-0.854333,0.520039,0.00253574,0.237201 beta-lactamase_2500_S68G,beta-lactamase_2500_68,TEM-1,beta-lactamase_2500,P62593,0.237208,NO,68,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-0.913,-2.934,2.021,,0.064,G,A,0.27,-1.03,2.824,,64.69,HPP,-1.37233,0.361275,0.000800065,0.237208 beta-lactamase_625_G249T,beta-lactamase_625_249,TEM-1,beta-lactamase_625,P62593,0.237217,NO,249,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.213352,0.00220169,0.237217 beta-lactamase_2500_R257D,beta-lactamase_2500_257,TEM-1,beta-lactamase_2500,P62593,0.237225,NO,257,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.361275,0.00756629,0.237225 kka2_1:2_P194K,kka2_1:2_194,Kka2,kka2_1:2,P00552,0.237277,NO,194,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.846,-3.507,2.661,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.295029,0.00314194,0.237277 beta-lactamase_625_I229H,beta-lactamase_625_229,TEM-1,beta-lactamase_625,P62593,0.237284,NO,229,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.267,-4.969,3.702,,0.083,E,B,0.48,-0.76,1.69,,50,HHH,-1.58767,0.213352,0.00477249,0.237284 kka2_1:2_R217Q,kka2_1:2_217,Kka2,kka2_1:2,P00552,0.237287,NO,217,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.158,-2.901,1.743,,0.252,T,A,1.2,-0.59,0.381,,52.27,ABH,-1.127,0.295029,0.0047191,0.237287 kka2_1:8_V49E,kka2_1:8_49,Kka2,kka2_1:8,P00552,0.237351,NO,49,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.614,-3.892,2.278,,,E,B,1.48,-0.77,1.31,,64.39,HHB,-1.3,0.100394,0.00615685,0.237351 kka2_1:8_V49E,kka2_1:8_49,Kka2,kka2_1:8,P00552,0.237351,NO,49,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.614,-3.892,2.278,,,E,B,1.48,-0.77,1.31,,64.39,HHB,-1.3,0.100394,0.00615685,0.237351 beta-lactamase_N130L,beta-lactamase_130,TEM-1,beta-lactamase,P62593,0.237387,NO,130,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-0.798,-3.583,2.785,5.26686,0.069,H,A,1.08,-0.74,,,,APP,-0.980667,0.221079,0.000683376,0.237387 beta-lactamase_T131I,beta-lactamase_131,TEM-1,beta-lactamase,P62593,0.237387,NO,131,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.328,-3.758,2.43,5.0548,,H,A,0.53,-0.69,3.306,,67.48,PPH,-1.00867,0.221079,0.00345886,0.237387 kka2_1:2_P194Y,kka2_1:2_194,Kka2,kka2_1:2,P00552,0.237418,NO,194,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.846,-4.438,3.592,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.295029,0.00314194,0.237418 PSD95pdz3_L353R,PSD95pdz3_353,PSD95pdz3,PSD95pdz3,P31016,0.237426,NO,353,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.347,-3.615,2.268,5.81136,,,,,17.3525,,,,AHB,-1.50533,0.0758425,0.000664742,0.237426 kka2_1:4_T51I,kka2_1:4_51,Kka2,kka2_1:4,P00552,0.237443,NO,51,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.199,-2.59,0.391,,0.05,E,B,0.82,-0.05,13.165,13.165,63.64,BPA,-1.76767,0.168804,0.00628861,0.237443 kka2_1:1_M116F,kka2_1:1_116,Kka2,kka2_1:1,P00552,0.237543,NO,116,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-2.482,-3.107,0.625,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.520039,0.00745147,0.237543 kka2_1:1_G74M,kka2_1:1_74,Kka2,kka2_1:1,P00552,0.237574,NO,74,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.18,-4.972,3.792,,0.621,T,l,0.75,0.2,15.356,15.356,64.39,POH,-1.91667,0.520039,0.00587035,0.237574 beta-lactamase_625_V78G,beta-lactamase_625_78,TEM-1,beta-lactamase_625,P62593,0.237578,NO,78,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.459,-2.817,1.358,,,H,A,0.44,-0.47,2.045,,63.64,HHH,-1.17833,0.213352,0.00492501,0.237578 beta-lactamase_156_F70R,beta-lactamase_156_70,TEM-1,beta-lactamase_156,P62593,0.237591,NO,70,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.169,-4.114,2.945,,,H,A,0.58,-1.34,1.918,,63.99,PHB,-0.980667,0.111618,0.00193499,0.237591 kka2_1:2_A41W,kka2_1:2_41,Kka2,kka2_1:2,P00552,0.237602,NO,41,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.879,-3.701,1.822,,0.184,.,B,0.46,-0.96,24.451,24.451,64.39,PHP,-2.477,0.295029,0.00543332,0.237602 beta-lactamase_625_V117R,beta-lactamase_625_117,TEM-1,beta-lactamase_625,P62593,0.237624,NO,117,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.53,-4.17,2.64,,,H,A,0.44,-0.34,1.23,,65.03,PHB,-1.741,0.213352,0.00467906,0.237624 kka2_1:1_A168N,kka2_1:1_168,Kka2,kka2_1:1,P00552,0.237661,NO,168,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.989,-3.164,1.175,,0.67,H,A,0.46,0.15,25.546,25.546,64.39,OHA,-2.12933,0.520039,0.00806773,0.237661 kka2_1:8_L259S,kka2_1:8_259,Kka2,kka2_1:8,P00552,0.237686,NO,259,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.088,-3.523,2.435,,0.036,H,A,1.59,-0.15,1.83,,48.48,BHH,-1.15167,0.100394,0.0206964,0.237686 kka2_1:8_L259S,kka2_1:8_259,Kka2,kka2_1:8,P00552,0.237686,NO,259,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.088,-3.523,2.435,,0.036,H,A,1.59,-0.15,1.83,,48.48,BHH,-1.15167,0.100394,0.0206964,0.237686 beta-lactamase_2500_V72G,beta-lactamase_2500_72,TEM-1,beta-lactamase_2500,P62593,0.237704,NO,72,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.658,-3.477,1.819,,,H,A,0.44,-1.03,2.079,,65.73,BHH,-1.32167,0.361275,0.00501194,0.237704 kka2_1:1_D52L,kka2_1:1_52,Kka2,kka2_1:1,P00552,0.237726,NO,52,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.271,-3.655,1.384,,0.22,E,B,0.75,0.8,2.64,,71.59,PAH,-2.38367,0.520039,0.00175694,0.237726 kka2_1:1_R258V,kka2_1:1_258,Kka2,kka2_1:1,P00552,0.23774,NO,258,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.626,-3.61,1.984,,0.316,H,A,1.2,-0.85,7.485,7.485,53.03,HBH,-1.25933,0.520039,0.00983174,0.23774 Pab1_F129G,Pab1_129,Pab1,Pab1,P04147,0.237845,NO,129,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.269,-3.454,2.185,,0.219,E,B,0.03,-0.07,1.307,,73.83,HHH,-1.27533,0.175299,0.000625182,0.237845 beta-lactamase_625_G240W,beta-lactamase_625_240,TEM-1,beta-lactamase_625,P62593,0.237861,NO,240,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.213352,0.00591201,0.237861 beta-lactamase_A133F,beta-lactamase_133,TEM-1,beta-lactamase,P62593,0.237877,NO,133,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.186,-4.224,3.038,4.86423,,H,A,0.55,-0.86,2.649,,67.83,HHP,-0.988333,0.221079,0.00468022,0.237877 beta-lactamase_G236F,beta-lactamase_236,TEM-1,beta-lactamase,P62593,0.237912,NO,236,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.784,-4.291,3.507,4.7915,0.241,,b,0.23,-0.59,1.883,,64.69,HOA,-1.36933,0.221079,0.00162372,0.237912 kka2_1:1_A229C,kka2_1:1_229,Kka2,kka2_1:1,P00552,0.238021,NO,229,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.739,-5.054,3.315,,0.32,H,A,0.46,-0.7,6.549,,63.64,HHA,-1.851,0.520039,0.00942138,0.238021 kka2_1:8_K50A,kka2_1:8_50,Kka2,kka2_1:8,P00552,0.238021,NO,50,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-0.833,-3.129,2.296,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.100394,0.00138626,0.238021 kka2_1:8_K50A,kka2_1:8_50,Kka2,kka2_1:8,P00552,0.238021,NO,50,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-0.833,-3.129,2.296,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.100394,0.00138626,0.238021 kka2_1:8_T187W,kka2_1:8_187,Kka2,kka2_1:8,P00552,0.238021,NO,187,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.273,-5.339,4.066,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.100394,0.00693073,0.238021 kka2_1:8_T187W,kka2_1:8_187,Kka2,kka2_1:8,P00552,0.238021,NO,187,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.273,-5.339,4.066,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.100394,0.00693073,0.238021 beta-lactamase_2500_I280Y,beta-lactamase_2500_280,TEM-1,beta-lactamase_2500,P62593,0.238025,NO,280,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.361275,0.0530888,0.238025 kka2_1:2_A237D,kka2_1:2_237,Kka2,kka2_1:2,P00552,0.238027,NO,237,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.12,-2.999,0.879,,0.068,H,A,0.46,-0.71,2.369,,92.05,HHA,-2.10433,0.295029,0.012257,0.238027 kka2_1:2_I207D,kka2_1:2_207,Kka2,kka2_1:2,P00552,0.238027,NO,207,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.175,-4.057,2.882,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.295029,0.00611824,0.238027 kka2_1:1_D216M,kka2_1:1_216,Kka2,kka2_1:1,P00552,0.238033,NO,216,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.785,-4.956,4.171,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.520039,0.00229969,0.238033 beta-lactamase_W208G,beta-lactamase_208,TEM-1,beta-lactamase,P62593,0.238046,NO,208,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-0.818,-3.358,2.54,5.26277,0.067,H,A,0.99,-0.65,,,,AHH,-1.44133,0.221079,0.00126609,0.238046 kka2_1:4_D216Q,kka2_1:4_216,Kka2,kka2_1:4,P00552,0.238054,NO,216,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.785,-3.726,2.941,,0.018,E,B,0.75,-0.51,0.112,,19.32,HAB,-0.970333,0.168804,0.00229969,0.238054 kka2_1:1_L126Q,kka2_1:1_126,Kka2,kka2_1:1,P00552,0.238115,NO,126,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.246,-3.15,1.904,,0.285,S,B,0.55,0.12,0.302,,51.89,PHA,-1.744,0.520039,0.0066485,0.238115 beta-lactamase_2500_L100P,beta-lactamase_2500_100,TEM-1,beta-lactamase_2500,P62593,0.238125,NO,100,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.218,-4.169,2.951,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.361275,0.00413885,0.238125 beta-lactamase_625_G240L,beta-lactamase_625_240,TEM-1,beta-lactamase_625,P62593,0.238127,NO,240,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.213352,0.00591201,0.238127 kka2_1:2_V97E,kka2_1:2_97,Kka2,kka2_1:2,P00552,0.238147,NO,97,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.453,-3.923,2.47,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.295029,0.00737869,0.238147 kka2_1:2_V36Q,kka2_1:2_36,Kka2,kka2_1:2,P00552,0.23819,NO,36,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-0.898,-4.235,3.337,,0.292,E,B,1.48,0.21,1.064,,52.27,HHH,-1.484,0.295029,0.00245633,0.23819 beta-lactamase_625_L74Q,beta-lactamase_625_74,TEM-1,beta-lactamase_625,P62593,0.238193,NO,74,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.296,-4.107,2.811,,,H,A,0.55,-0.91,0.895,,50,HHO,-1.34933,0.213352,0.00493255,0.238193 kka2_1:8_L70K,kka2_1:8_70,Kka2,kka2_1:8,P00552,0.238356,NO,70,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.017,-3.772,2.755,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.100394,0.00411884,0.238356 kka2_1:8_L70K,kka2_1:8_70,Kka2,kka2_1:8,P00552,0.238356,NO,70,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.017,-3.772,2.755,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.100394,0.00411884,0.238356 kka2_1:1_G95M,kka2_1:1_95,Kka2,kka2_1:1,P00552,0.238402,NO,95,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-2.403,-4.756,2.353,,0.126,E,B,0.29,-0.74,7.822,,71.59,HOA,-2.198,0.520039,0.00743616,0.238402 kka2_1:2_G30F,kka2_1:2_30,Kka2,kka2_1:2,P00552,0.238455,NO,30,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.596,-4.32,3.724,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.295029,0.00159208,0.238455 beta-lactamase_625_A185M,beta-lactamase_625_185,TEM-1,beta-lactamase_625,P62593,0.238492,NO,185,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.406,-4.39,2.984,,,H,A,0.46,-1.02,0.365,,65.03,HHP,-1.84033,0.213352,0.00467449,0.238492 kka2_1:1_L7I,kka2_1:1_7,Kka2,kka2_1:1,P00552,0.238504,NO,7,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.926,-3.353,1.427,,,,,,,18.934,18.934,71.59,OHB,-2.12333,0.520039,0.00269456,0.238504 kka2_1:1_L7Y,kka2_1:1_7,Kka2,kka2_1:1,P00552,0.238504,NO,7,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.926,-3.823,1.897,,,,,,,18.934,18.934,71.59,OHB,-2.12333,0.520039,0.00269456,0.238504 kka2_1:2_W236E,kka2_1:2_236,Kka2,kka2_1:2,P00552,0.23855,NO,236,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-1.363,-3.989,2.626,,0.303,H,A,1.51,-0.76,5.58,,48.48,AHH,-1.81267,0.295029,0.0088796,0.23855 beta-lactamase_2500_K232C,beta-lactamase_2500_232,TEM-1,beta-lactamase_2500,P62593,0.238562,NO,232,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.012,-5.13,4.118,,,E,B,2.34,-1.1,3.048,,65.03,ABP,-1.238,0.361275,0.00313441,0.238562 kka2_1:4_L212K,kka2_1:4_212,Kka2,kka2_1:4,P00552,0.238565,NO,212,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.904,-3.732,2.828,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.168804,0.0031426,0.238565 beta-lactamase_625_R162V,beta-lactamase_625_162,TEM-1,beta-lactamase_625,P62593,0.238572,NO,162,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.016,-3.642,2.626,,0.124,S,B,1.2,-0.37,1.445,,64.69,ABH,-1.25,0.213352,0.000561334,0.238572 kka2_1:1_L174K,kka2_1:1_174,Kka2,kka2_1:1,P00552,0.23858,NO,174,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.952,-3.744,2.792,,,H,A,0.55,-0.31,13.276,13.276,51.89,BHB,-2.08533,0.520039,0.00438501,0.23858 beta-lactamase_625_G142M,beta-lactamase_625_142,TEM-1,beta-lactamase_625,P62593,0.238619,NO,142,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.707,-4.893,4.186,,0.034,,p,0.29,-0.64,1.35,,64.69,OOO,-0.834,0.213352,0.00060149,0.238619 beta-lactamase_625_A124P,beta-lactamase_625_124,TEM-1,beta-lactamase_625,P62593,0.238667,NO,124,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.181,-3.759,2.578,,,H,A,0.46,-0.9,2.027,,64.34,HHH,-1.152,0.213352,0.00481399,0.238667 kka2_1:1_L243W,kka2_1:1_243,Kka2,kka2_1:1,P00552,0.238667,NO,243,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-2.651,-5.55,2.899,,0.277,H,A,0.55,-0.67,4.334,,92.05,HHH,-2.03767,0.520039,0.00884927,0.238667 beta-lactamase_2500_T179C,beta-lactamase_2500_179,TEM-1,beta-lactamase_2500,P62593,0.238707,NO,179,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.085,-4.712,3.627,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.361275,0.00226045,0.238707 beta-lactamase_156_N130R,beta-lactamase_156_130,TEM-1,beta-lactamase_156,P62593,0.238719,NO,130,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-0.798,-3.483,2.685,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.111618,0.000683376,0.238719 E1_Ubiquitin_G75W,E1_Ubiquitin_75,Uba1,E1_Ubiquitin,P0CG63,0.238727,NO,75,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.999,-5.018,4.019,,0.552,T,A,0.75,0.9,4.369,,83.73,BOO,-1.1,0.18783,0.00153276,0.238727 beta-lactamase_2500_L55D,beta-lactamase_2500_55,TEM-1,beta-lactamase_2500,P62593,0.238821,NO,55,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.86,-4.094,2.234,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.361275,0.00403741,0.238821 kka2_1:2_L260C,kka2_1:2_260,Kka2,kka2_1:2,P00552,0.238821,NO,260,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.741,-4.665,3.924,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.295029,0.0233782,0.238821 kka2_1:1_E199I,kka2_1:1_199,Kka2,kka2_1:1,P00552,0.23883,NO,199,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.234,-3.975,1.741,,0.508,E,B,1.04,-0.43,3.012,,65.53,HAP,-2.133,0.520039,0.00854122,0.23883 beta-lactamase_625_T179R,beta-lactamase_625_179,TEM-1,beta-lactamase_625,P62593,0.238832,NO,179,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.085,-3.749,2.664,,,E,B,0.22,-1.38,0.367,,73.08,PPH,-1.557,0.213352,0.00226045,0.238832 beta-lactamase_156_T107D,beta-lactamase_156_107,TEM-1,beta-lactamase_156,P62593,0.238857,NO,107,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.117,-3.478,2.361,,,G,A,0.22,-0.06,0.341,,67.83,HPA,-1.265,0.111618,0.00239347,0.238857 beta-lactamase_156_M184E,beta-lactamase_156_184,TEM-1,beta-lactamase_156,P62593,0.238858,NO,184,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.593,-3.708,2.115,,,H,A,0.55,-0.87,1.671,,62.94,HHH,-1.41,0.111618,0.00356019,0.238858 kka2_1:2_F263G,kka2_1:2_263,Kka2,kka2_1:2,P00552,0.238861,NO,263,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-0.911,-3.675,2.764,,0.006,G,A,1.62,-0.12,5.275,,45.83,AHH,-0.92,0.295029,0.0172454,0.238861 beta-lactamase_L223D,beta-lactamase_223,TEM-1,beta-lactamase,P62593,0.238873,NO,223,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.055,-4.067,3.012,5.42318,0.27,,B,1.3,0.09,1.511,,74.48,HHO,-1.35033,0.221079,0.00372793,0.238873 kka2_1:4_C77E,kka2_1:4_77,Kka2,kka2_1:4,P00552,0.238887,NO,77,C,E,CE,Special,negativeCharge,5.07,3.22,-1.85,170,121,147,26,108.5,138.4,29.9,-1.477,-3.891,2.414,,0.229,B,b,0.46,-0.57,2.499,,63.26,OOH,-1.55667,0.168804,0.00441216,0.238887 kka2_1:1_A34F,kka2_1:1_34,Kka2,kka2_1:1,P00552,0.23891,NO,34,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.928,-4.127,3.199,,0.417,.,B,0.46,2.29,0.262,,52.27,AHH,-1.747,0.520039,0.00343484,0.23891 kka2_1:2_F206E,kka2_1:2_206,Kka2,kka2_1:2,P00552,0.238921,NO,206,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.349,-3.931,2.582,,0.006,E,B,0.58,-1.21,0.978,,63.64,OHH,-1.04,0.295029,0.00936868,0.238921 beta-lactamase_2500_R91P,beta-lactamase_2500_91,TEM-1,beta-lactamase_2500,P62593,0.238996,NO,91,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.392,-3.876,2.484,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.361275,0.00380226,0.238996 beta-lactamase_625_L248D,beta-lactamase_625_248,TEM-1,beta-lactamase_625,P62593,0.238997,NO,248,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.213352,0.00428493,0.238997 beta-lactamase_156_L160R,beta-lactamase_156_160,TEM-1,beta-lactamase_156,P62593,0.238998,NO,160,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.977,-4.03,3.053,,0.022,,B,0.55,-0.6,1.095,,44.41,BHA,-0.936,0.111618,0.00193775,0.238998 kka2_1:1_D156I,kka2_1:1_156,Kka2,kka2_1:1,P00552,0.23903,NO,156,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.696,-4.017,2.321,,0.884,T,A,0.75,1.87,1.044,,65.53,PAA,-1.765,0.520039,0.00926998,0.23903 beta-lactamase_2500_L146N,beta-lactamase_2500_146,TEM-1,beta-lactamase_2500,P62593,0.239071,NO,146,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.462,-4.208,2.746,,0.007,H,A,0.55,-0.56,1.578,,64.69,AHP,-1.656,0.361275,0.00474542,0.239071 beta-lactamase_2500_L284K,beta-lactamase_2500_284,TEM-1,beta-lactamase_2500,P62593,0.239091,NO,284,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.981,-3.504,1.523,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.361275,0.0686156,0.239091 beta-lactamase_625_N168W,beta-lactamase_625_168,TEM-1,beta-lactamase_625,P62593,0.239186,NO,168,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-1.029,-5.48,4.451,,0.113,G,A,0.61,-0.4,1.014,,44.41,HPA,-1.13233,0.213352,0.00288667,0.239186 beta-lactamase_2500_S68V,beta-lactamase_2500_68,TEM-1,beta-lactamase_2500,P62593,0.239199,NO,68,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-0.913,-3.578,2.665,,0.064,G,A,0.27,-1.03,2.824,,64.69,HPP,-1.37233,0.361275,0.000800065,0.239199 kka2_1:2_L212E,kka2_1:2_212,Kka2,kka2_1:2,P00552,0.239201,NO,212,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.904,-3.881,2.977,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.295029,0.0031426,0.239201 kka2_1:1_F263C,kka2_1:1_263,Kka2,kka2_1:1,P00552,0.239211,NO,263,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-0.911,-4.889,3.978,,0.006,G,A,0.58,-0.12,2.284,,45.83,AHH,-0.92,0.520039,0.0172454,0.239211 Pab1_N127F,Pab1_127,Pab1,Pab1,P04147,0.23922,NO,127,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-1.079,-4.109,3.03,,0.138,E,B,1.05,-0.51,,,,OPH,-1.13633,0.175299,0.000805159,0.23922 beta-lactamase_G142V,beta-lactamase_142,TEM-1,beta-lactamase,P62593,0.239293,NO,142,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.707,-3.751,3.044,4.55474,0.034,,p,0.77,-0.64,1.947,,64.69,OOO,-0.834,0.221079,0.00060149,0.239293 kka2_1:2_L259Y,kka2_1:2_259,Kka2,kka2_1:2,P00552,0.239304,NO,259,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.088,-4.087,2.999,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.295029,0.0206964,0.239304 kka2_1:8_L47D,kka2_1:8_47,Kka2,kka2_1:8,P00552,0.239357,NO,47,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.265,-4.048,2.783,,0.139,E,B,1.59,-0.86,5.086,,63.26,HHH,-1.77933,0.100394,0.00509386,0.239357 kka2_1:8_L47D,kka2_1:8_47,Kka2,kka2_1:8,P00552,0.239357,NO,47,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.265,-4.048,2.783,,0.139,E,B,1.59,-0.86,5.086,,63.26,HHH,-1.77933,0.100394,0.00509386,0.239357 kka2_1:1_M116D,kka2_1:1_116,Kka2,kka2_1:1,P00552,0.239367,NO,116,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-2.482,-4.161,1.679,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.520039,0.00745147,0.239367 beta-lactamase_2500_A133M,beta-lactamase_2500_133,TEM-1,beta-lactamase_2500,P62593,0.239376,NO,133,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.186,-4.694,3.508,,,H,A,0.46,-0.86,2.649,,67.83,HHP,-0.988333,0.361275,0.00468022,0.239376 kka2_1:1_V75Y,kka2_1:1_75,Kka2,kka2_1:1,P00552,0.23945,NO,75,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-2.06,-4.054,1.994,,0.042,.,B,0.44,-0.2,2.815,,71.59,OHO,-1.563,0.520039,0.00693733,0.23945 beta-lactamase_625_N134A,beta-lactamase_625_134,TEM-1,beta-lactamase_625,P62593,0.23947,NO,134,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-0.879,-3.3,2.421,,0.138,H,A,0.61,-0.6,3.776,,53.15,HPH,-1.02233,0.213352,0.000644786,0.23947 beta-lactamase_156_D177M,beta-lactamase_156_177,TEM-1,beta-lactamase_156,P62593,0.239516,NO,177,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.967,-4.928,3.961,,0.006,T,L,0.75,-1.02,2.072,,64.69,BAP,-0.873667,0.111618,0.000864022,0.239516 kka2_1:8_F263G,kka2_1:8_263,Kka2,kka2_1:8,P00552,0.239524,NO,263,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-0.911,-3.675,2.764,,0.006,G,A,1.62,-0.12,0.928,,45.83,AHH,-0.92,0.100394,0.0172454,0.239524 kka2_1:8_F263G,kka2_1:8_263,Kka2,kka2_1:8,P00552,0.239524,NO,263,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-0.911,-3.675,2.764,,0.006,G,A,1.62,-0.12,0.928,,45.83,AHH,-0.92,0.100394,0.0172454,0.239524 kka2_1:4_L47D,kka2_1:4_47,Kka2,kka2_1:4,P00552,0.239546,NO,47,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.265,-4.048,2.783,,0.139,E,B,0.55,-0.86,2.369,,63.26,HHH,-1.77933,0.168804,0.00509386,0.239546 beta-lactamase_156_D129N,beta-lactamase_156_129,TEM-1,beta-lactamase_156,P62593,0.239587,NO,129,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.816,-3.272,2.456,,,,B,0.75,-0.69,1.924,,34.97,PAP,-0.818,0.111618,0.00109178,0.239587 kka2_1:2_G151W,kka2_1:2_151,Kka2,kka2_1:2,P00552,0.2396,NO,151,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.873,-5.3,4.427,,0.678,T,l,0.29,1.36,1.357,,49.62,HOH,-1.11433,0.295029,0.00339918,0.2396 beta-lactamase_2500_Y44D,beta-lactamase_2500_44,TEM-1,beta-lactamase_2500,P62593,0.239632,NO,44,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-2.547,-4.061,1.514,,,E,B,0.21,-0.45,2.184,,73.78,OHH,-1.86267,0.361275,0.00426364,0.239632 beta-lactamase_39_M66K,beta-lactamase_39_66,TEM-1,beta-lactamase_39,P62593,0.239638,NO,66,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.362,-3.657,2.295,,0.013,,A,0.55,-0.7,1.319,,73.08,OHH,-1.49567,0.0495842,0.00412876,0.239638 Pab1_Y197P,Pab1_197,Pab1,Pab1,P04147,0.23964,NO,197,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-1.345,-4.1,2.755,,,,,,,0.891,,80.42,HHH,-1.41767,0.175299,0.00302474,0.23964 beta-lactamase_39_L188R,beta-lactamase_39_188,TEM-1,beta-lactamase_39,P62593,0.23965,NO,188,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.166,-3.976,2.81,,,H,A,0.55,-0.3,2.982,,60.14,PHB,-1.47033,0.0495842,0.00295687,0.23965 kka2_1:1_R258A,kka2_1:1_258,Kka2,kka2_1:1,P00552,0.239657,NO,258,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.626,-3.206,1.58,,0.316,H,A,1.2,-0.85,7.485,7.485,53.03,HBH,-1.25933,0.520039,0.00983174,0.239657 kka2_1:1_H162P,kka2_1:1_162,Kka2,kka2_1:1,P00552,0.239682,NO,162,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-2.319,-4.047,1.728,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.520039,0.00616145,0.239682 beta-lactamase_2500_V260Y,beta-lactamase_2500_260,TEM-1,beta-lactamase_2500,P62593,0.239752,NO,260,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.101,-3.316,2.215,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.361275,0.00471757,0.239752 kka2_1:2_A144N,kka2_1:2_144,Kka2,kka2_1:2,P00552,0.239781,NO,144,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.859,-4.009,3.15,,,H,A,0.46,0.21,6.844,,52.65,BHB,-1.72933,0.295029,0.00231095,0.239781 beta-lactamase_156_G76N,beta-lactamase_156_76,TEM-1,beta-lactamase_156,P62593,0.239838,NO,76,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.189,-3.655,2.466,,,H,A,0.29,-0.67,3.059,,67.83,OOH,-1.22267,0.111618,0.00476637,0.239838 kka2_1:2_S105F,kka2_1:2_105,Kka2,kka2_1:2,P00552,0.239842,NO,105,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.945,-4.371,2.426,,0.056,S,B,0.27,-1.04,3.442,,65.53,PPB,-2.17033,0.295029,0.00847233,0.239842 kka2_1:8_V153D,kka2_1:8_153,Kka2,kka2_1:8,P00552,0.239857,NO,153,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.092,-4.005,2.913,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.100394,0.00501119,0.239857 kka2_1:8_V153D,kka2_1:8_153,Kka2,kka2_1:8,P00552,0.239857,NO,153,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.092,-4.005,2.913,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.100394,0.00501119,0.239857 kka2_1:1_K50A,kka2_1:1_50,Kka2,kka2_1:1,P00552,0.239887,NO,50,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-0.833,-3.129,2.296,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.520039,0.00138626,0.239887 kka2_1:1_A229W,kka2_1:1_229,Kka2,kka2_1:1,P00552,0.239906,NO,229,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.739,-5.507,3.768,,0.32,H,A,0.46,-0.7,6.549,,63.64,HHA,-1.851,0.520039,0.00942138,0.239906 kka2_1:1_V198I,kka2_1:1_198,Kka2,kka2_1:1,P00552,0.239975,NO,198,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.719,-3.396,1.677,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.520039,0.00835002,0.239975 kka2_1:1_A237K,kka2_1:1_237,Kka2,kka2_1:1,P00552,0.239976,NO,237,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.12,-3.814,1.694,,0.068,H,A,0.46,-0.71,2.369,,92.05,HHA,-2.10433,0.520039,0.012257,0.239976 beta-lactamase_I45W,beta-lactamase_45,TEM-1,beta-lactamase,P62593,0.24006,NO,45,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-2.421,-5.294,2.873,5.31505,,E,B,1,-0.3,2.256,,77.62,HHA,-2.30267,0.221079,0.00452842,0.24006 kka2_1:1_L260Q,kka2_1:1_260,Kka2,kka2_1:1,P00552,0.240141,NO,260,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.741,-4.153,3.412,,0.022,H,A,0.55,-0.52,,,,HHA,-0.845667,0.520039,0.0233782,0.240141 hsp90_W585T,hsp90_585,hsp90,hsp90,P02829,0.240169,NO,585,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-4.251,-2.8,0,5.31455,0.508,,B,1.22,0.43,,,,OHP,-3.17533,0.368192,0.000222939,0.240169 kka2_1:8_L212K,kka2_1:8_212,Kka2,kka2_1:8,P00552,0.240189,NO,212,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.904,-3.732,2.828,,,,B,1.59,-0.78,1.708,,42.42,BHO,-0.799667,0.100394,0.0031426,0.240189 kka2_1:8_L212K,kka2_1:8_212,Kka2,kka2_1:8,P00552,0.240189,NO,212,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.904,-3.732,2.828,,,,B,1.59,-0.78,1.708,,42.42,BHO,-0.799667,0.100394,0.0031426,0.240189 kka2_1:1_G151L,kka2_1:1_151,Kka2,kka2_1:1,P00552,0.24019,NO,151,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.873,-3.818,2.945,,0.678,T,l,0.29,1.36,0.226,,49.62,HOH,-1.11433,0.520039,0.00339918,0.24019 beta-lactamase_2500_L248Q,beta-lactamase_2500_248,TEM-1,beta-lactamase_2500,P62593,0.24034,NO,248,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.361275,0.00428493,0.24034 beta-lactamase_2500_Y95Q,beta-lactamase_2500_95,TEM-1,beta-lactamase_2500,P62593,0.240365,NO,95,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-1.715,-4.267,2.552,,0.122,,b,0.21,-0.37,2.914,,77.62,BHP,-2.16167,0.361275,0.00479449,0.240365 beta-lactamase_2500_L191K,beta-lactamase_2500_191,TEM-1,beta-lactamase_2500,P62593,0.240366,NO,191,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.087,-3.741,2.654,,,H,A,0.55,0.09,1.703,,63.29,BHH,-1.445,0.361275,0.00263549,0.240366 kka2_1:1_T73L,kka2_1:1_73,Kka2,kka2_1:1,P00552,0.240413,NO,73,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.51,-2.574,0.064,,0.309,H,A,0.22,0.35,4.126,,56.06,PPO,-2.02333,0.520039,0.00628605,0.240413 kka2_1:2_E262N,kka2_1:2_262,Kka2,kka2_1:2,P00552,0.240432,NO,262,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-0.829,-3.499,2.67,,0.059,G,A,1.04,-0.18,2.383,,42.42,AAH,-0.816,0.295029,0.0191586,0.240432 kka2_1:1_P194M,kka2_1:1_194,Kka2,kka2_1:1,P00552,0.240443,NO,194,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.846,-4.773,3.927,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.520039,0.00314194,0.240443 beta-lactamase_2500_W288K,beta-lactamase_2500_288,TEM-1,beta-lactamase_2500,P62593,0.240476,NO,288,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,,,,,,,,,,,,,BHO,,0.361275,,0.240476 E1_Ubiquitin_R72C,E1_Ubiquitin_72,Uba1,E1_Ubiquitin,P0CG63,0.240495,NO,72,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.184,-4.904,3.72,,0.077,,B,0.16,-0.1,,,,HBH,-1.08733,0.18783,0.00129853,0.240495 beta-lactamase_2500_G243P,beta-lactamase_2500_243,TEM-1,beta-lactamase_2500,P62593,0.240522,NO,243,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.361275,0.00464034,0.240522 beta-lactamase_625_S128C,beta-lactamase_625_128,TEM-1,beta-lactamase_625,P62593,0.240542,NO,128,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-0.84,-4.637,3.797,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.213352,0.00071483,0.240542 beta-lactamase_2500_A247R,beta-lactamase_2500_247,TEM-1,beta-lactamase_2500,P62593,0.240615,NO,247,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.361275,0.00611275,0.240615 beta-lactamase_625_I277P,beta-lactamase_625_277,TEM-1,beta-lactamase_625,P62593,0.24065,NO,277,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.213352,0.0169305,0.24065 kka2_1:1_A108N,kka2_1:1_108,Kka2,kka2_1:1,P00552,0.240708,NO,108,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.061,-3.827,1.766,,0.243,.,B,0.46,-1.34,3.156,,71.59,HHO,-1.57033,0.520039,0.00751209,0.240708 beta-lactamase_I256E,beta-lactamase_256,TEM-1,beta-lactamase,P62593,0.240743,NO,256,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.621,-3.947,2.326,5.3196,,E,B,1,-0.84,1.615,,73.08,BHH,-1.80667,0.221079,0.00710634,0.240743 beta-lactamase_2500_V117E,beta-lactamase_2500_117,TEM-1,beta-lactamase_2500,P62593,0.240748,NO,117,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.53,-3.909,2.379,,,H,A,0.44,-0.34,1.23,,65.03,PHB,-1.741,0.361275,0.00467906,0.240748 beta-lactamase_625_G236L,beta-lactamase_625_236,TEM-1,beta-lactamase_625,P62593,0.240765,NO,236,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.784,-3.712,2.928,,0.241,,b,0.29,-0.59,3.506,,64.69,HOO,-1.025,0.213352,0.00162372,0.240765 beta-lactamase_2500_I244D,beta-lactamase_2500_244,TEM-1,beta-lactamase_2500,P62593,0.240775,NO,244,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.555,-3.943,2.388,,,E,B,0.48,-0.84,1.683,,77.62,OHH,-1.385,0.361275,0.00605379,0.240775 kka2_1:2_I228F,kka2_1:2_228,Kka2,kka2_1:2,P00552,0.240788,NO,228,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.142,-3.751,2.609,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.295029,0.00458834,0.240788 kka2_1:2_L232D,kka2_1:2_232,Kka2,kka2_1:2,P00552,0.240826,NO,232,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.514,-4.122,2.608,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.295029,0.00800103,0.240826 kka2_1:4_A119M,kka2_1:4_119,Kka2,kka2_1:4,P00552,0.240848,NO,119,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.073,-4.566,3.493,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.168804,0.00441074,0.240848 kka2_1:8_D190F,kka2_1:8_190,Kka2,kka2_1:8,P00552,0.240853,NO,190,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.708,-4.32,3.612,,0.213,S,b,0.29,-0.82,,,,OAH,-0.711667,0.100394,0.00247989,0.240853 kka2_1:8_D190F,kka2_1:8_190,Kka2,kka2_1:8,P00552,0.240853,NO,190,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.708,-4.32,3.612,,0.213,S,b,0.29,-0.82,,,,OAH,-0.711667,0.100394,0.00247989,0.240853 beta-lactamase_625_K232Y,beta-lactamase_625_232,TEM-1,beta-lactamase_625,P62593,0.240883,NO,232,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.012,-4.205,3.193,,,E,B,2.34,-1.1,1.992,,65.03,ABP,-1.238,0.213352,0.00313441,0.240883 kka2_1:1_V185M,kka2_1:1_185,Kka2,kka2_1:1,P00552,0.240887,NO,185,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.045,-3.067,2.022,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.520039,0.00367031,0.240887 beta-lactamase_625_W288C,beta-lactamase_625_288,TEM-1,beta-lactamase_625,P62593,0.240898,NO,288,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,,,,,,,,,,,,,BHO,,0.213352,,0.240898 kka2_1:2_I207C,kka2_1:2_207,Kka2,kka2_1:2,P00552,0.240901,NO,207,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.175,-4.752,3.577,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.295029,0.00611824,0.240901 beta-lactamase_G234Y,beta-lactamase_234,TEM-1,beta-lactamase,P62593,0.240911,NO,234,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.62,-4.387,3.767,4.24221,0.023,E,B,0.46,-0.86,,,,POH,-1.25733,0.221079,0.000889577,0.240911 kka2_1:1_G99K,kka2_1:1_99,Kka2,kka2_1:1,P00552,0.240922,NO,99,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.596,-3.71,3.114,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.520039,0.00186055,0.240922 kka2_1:1_R217D,kka2_1:1_217,Kka2,kka2_1:1,P00552,0.240922,NO,217,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.158,-3.819,2.661,,0.252,T,A,1.2,-0.59,0.381,,52.27,ABH,-1.127,0.520039,0.0047191,0.240922 kka2_1:1_R217F,kka2_1:1_217,Kka2,kka2_1:1,P00552,0.240922,NO,217,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.158,-4.264,3.106,,0.252,T,A,1.2,-0.59,0.381,,52.27,ABH,-1.127,0.520039,0.0047191,0.240922 beta-lactamase_625_S233Y,beta-lactamase_625_233,TEM-1,beta-lactamase_625,P62593,0.240942,NO,233,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.886,-4.293,2.407,,0.016,E,B,0.27,-1.01,1.773,,77.62,BPO,-1.17267,0.213352,0.00311415,0.240942 kka2_1:1_L47G,kka2_1:1_47,Kka2,kka2_1:1,P00552,0.24095,NO,47,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.265,-3.713,2.448,,0.139,E,B,0.55,-0.86,14.593,14.593,63.26,HHH,-1.77933,0.520039,0.00509386,0.24095 beta-lactamase_2500_L191N,beta-lactamase_2500_191,TEM-1,beta-lactamase_2500,P62593,0.240955,NO,191,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.087,-4.164,3.077,,,H,A,0.55,0.09,1.703,,63.29,BHH,-1.445,0.361275,0.00263549,0.240955 kka2_1:4_A215I,kka2_1:4_215,Kka2,kka2_1:4,P00552,0.240975,NO,215,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.968,-3.723,2.755,,0.039,E,B,0.46,-0.59,0.754,,50.38,HHA,-1.00467,0.168804,0.00529129,0.240975 PSD95pdz3_V362P,PSD95pdz3_362,PSD95pdz3,PSD95pdz3,P31016,0.240978,NO,362,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.465,-3.561,2.096,4.99436,,,,,19.6443,,,,PHP,-1.46467,0.0758425,0.000538527,0.240978 beta-lactamase_625_W208G,beta-lactamase_625_208,TEM-1,beta-lactamase_625,P62593,0.241013,NO,208,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-0.818,-3.358,2.54,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.213352,0.00126609,0.241013 kka2_1:1_Y218G,kka2_1:1_218,Kka2,kka2_1:1,P00552,0.241045,NO,218,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-1.438,-3.625,2.187,,0.122,H,A,1.25,-0.69,3.059,,56.06,BHP,-1.17533,0.520039,0.0126098,0.241045 kka2_1:1_W236P,kka2_1:1_236,Kka2,kka2_1:1,P00552,0.241052,NO,236,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-1.363,-4.32,2.957,,0.303,H,A,1.51,-0.76,12.263,12.263,48.48,AHH,-1.81267,0.520039,0.0088796,0.241052 beta-lactamase_625_A246Y,beta-lactamase_625_246,TEM-1,beta-lactamase_625,P62593,0.241055,NO,246,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.121,-4.018,1.897,,0.01,E,B,0.46,-1.01,1.201,,73.78,HHH,-1.55633,0.213352,0.00569458,0.241055 kka2_1:2_R211V,kka2_1:2_211,Kka2,kka2_1:2,P00552,0.24107,NO,211,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-0.899,-3.805,2.906,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.295029,0.00204888,0.24107 kka2_1:4_F171N,kka2_1:4_171,Kka2,kka2_1:4,P00552,0.241089,NO,171,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.326,-4.165,2.839,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.168804,0.00821426,0.241089 kka2_1:1_T187G,kka2_1:1_187,Kka2,kka2_1:1,P00552,0.241124,NO,187,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.273,-3.394,2.121,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.520039,0.00693073,0.241124 kka2_1:4_R202W,kka2_1:4_202,Kka2,kka2_1:4,P00552,0.241195,NO,202,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.761,-5.54,3.779,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.168804,0.00696498,0.241195 beta-lactamase_156_S128L,beta-lactamase_156_128,TEM-1,beta-lactamase_156,P62593,0.241251,NO,128,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-0.84,-3.358,2.518,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.111618,0.00071483,0.241251 beta-lactamase_2500_V42H,beta-lactamase_2500_42,TEM-1,beta-lactamase_2500,P62593,0.241252,NO,42,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.564,-4.991,3.427,,0.017,E,B,0.44,-0.51,1.86,,63.99,BHO,-1.042,0.361275,0.00404515,0.241252 kka2_1:2_A224L,kka2_1:2_224,Kka2,kka2_1:2,P00552,0.24126,NO,224,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.977,-3.204,2.227,,,H,A,0.46,-1.26,1.646,,63.64,HHP,-1.41033,0.295029,0.00352047,0.24126 kka2_1:2_N200C,kka2_1:2_200,Kka2,kka2_1:2,P00552,0.241293,NO,200,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-2.446,-5.276,2.83,,0.756,T,L,0.61,-0.08,2.836,,64.39,APO,-2.08,0.295029,0.00838549,0.241293 beta-lactamase_625_N134G,beta-lactamase_625_134,TEM-1,beta-lactamase_625,P62593,0.241296,NO,134,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-0.879,-2.976,2.097,,0.138,H,A,0.61,-0.6,3.776,,53.15,HPH,-1.02233,0.213352,0.000644786,0.241296 beta-lactamase_156_K232Y,beta-lactamase_156_232,TEM-1,beta-lactamase_156,P62593,0.241344,NO,232,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.012,-4.205,3.193,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.111618,0.00313441,0.241344 kka2_1:1_T72D,kka2_1:1_72,Kka2,kka2_1:1,P00552,0.241358,NO,72,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.38,-3.042,0.662,,0.784,H,A,0.22,0.29,10.43,10.43,65.53,HPP,-2.238,0.520039,0.00750756,0.241358 beta-lactamase_625_D174P,beta-lactamase_625_174,TEM-1,beta-lactamase_625,P62593,0.241415,NO,174,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.738,-3.655,2.917,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.213352,0.00125633,0.241415 kka2_1:4_L92R,kka2_1:4_92,Kka2,kka2_1:4,P00552,0.241421,NO,92,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.893,-4.021,3.128,,0.007,E,B,0.55,-0.19,1.447,,63.26,HHH,-0.962,0.168804,0.00307177,0.241421 beta-lactamase_625_L55P,beta-lactamase_625_55,TEM-1,beta-lactamase_625,P62593,0.241441,NO,55,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.86,-4.226,2.366,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.213352,0.00403741,0.241441 kka2_1:1_A117D,kka2_1:1_117,Kka2,kka2_1:1,P00552,0.241481,NO,117,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.828,-3.786,2.958,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.520039,0.00282984,0.241481 kka2_1:1_Q100I,kka2_1:1_100,Kka2,kka2_1:1,P00552,0.241491,NO,100,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.77,-3.068,0.298,,0.646,E,B,0.4,-0.79,15.116,15.116,71.59,OPA,-1.46467,0.520039,0.0066405,0.241491 beta-lactamase_625_K232Q,beta-lactamase_625_232,TEM-1,beta-lactamase_625,P62593,0.241498,NO,232,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.012,-3.492,2.48,,,E,B,2.34,-1.1,1.992,,65.03,ABP,-1.238,0.213352,0.00313441,0.241498 kka2_1:1_S32H,kka2_1:1_32,Kka2,kka2_1:1,P00552,0.24152,NO,32,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-0.804,-4.483,3.679,,0.768,S,b,0.27,3.75,,,,OPA,-1.74533,0.520039,0.00149998,0.24152 kka2_1:1_S32M,kka2_1:1_32,Kka2,kka2_1:1,P00552,0.24152,NO,32,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-0.804,-4.508,3.704,,0.768,S,b,0.27,3.75,,,,OPA,-1.74533,0.520039,0.00149998,0.24152 beta-lactamase_2500_R176I,beta-lactamase_2500_176,TEM-1,beta-lactamase_2500,P62593,0.241525,NO,176,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-0.863,-4.01,3.147,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.361275,0.00105554,0.241525 kka2_1:2_V185Y,kka2_1:2_185,Kka2,kka2_1:2,P00552,0.241585,NO,185,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.045,-4.096,3.051,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.295029,0.00367031,0.241585 kka2_1:4_S105E,kka2_1:4_105,Kka2,kka2_1:4,P00552,0.241644,NO,105,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.945,-2.784,0.839,,0.056,S,B,0.77,-1.04,3.442,,65.53,PPB,-2.17033,0.168804,0.00847233,0.241644 kka2_1:8_G189M,kka2_1:8_189,Kka2,kka2_1:8,P00552,0.241682,NO,189,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.596,-4.958,4.362,,0.034,S,l,0.75,-0.99,,,,BOA,-0.739,0.100394,0.00253688,0.241682 kka2_1:8_G189M,kka2_1:8_189,Kka2,kka2_1:8,P00552,0.241682,NO,189,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.596,-4.958,4.362,,0.034,S,l,0.75,-0.99,,,,BOA,-0.739,0.100394,0.00253688,0.241682 kka2_1:4_I207E,kka2_1:4_207,Kka2,kka2_1:4,P00552,0.241807,NO,207,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.175,-3.934,2.759,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.168804,0.00611824,0.241807 kka2_1:1_G205Y,kka2_1:1_205,Kka2,kka2_1:1,P00552,0.241846,NO,205,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.596,-4.416,3.82,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.520039,0.00221855,0.241846 kka2_1:8_C77Y,kka2_1:8_77,Kka2,kka2_1:8,P00552,0.241847,NO,77,C,Y,CY,Special,Hydrophobic,5.07,5.66,0.59,194,121,181,60,108.5,193.6,85.1,-1.477,-4.33,2.853,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.100394,0.00441216,0.241847 kka2_1:8_C77Y,kka2_1:8_77,Kka2,kka2_1:8,P00552,0.241847,NO,77,C,Y,CY,Special,Hydrophobic,5.07,5.66,0.59,194,121,181,60,108.5,193.6,85.1,-1.477,-4.33,2.853,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.100394,0.00441216,0.241847 beta-lactamase_156_V31R,beta-lactamase_156_31,TEM-1,beta-lactamase_156,P62593,0.241856,NO,31,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.822,-4.173,2.351,,,H,A,0.44,-0.46,4.126,,73.78,BHB,-2.03767,0.111618,0.00478065,0.241856 beta-lactamase_2500_T158Q,beta-lactamase_2500_158,TEM-1,beta-lactamase_2500,P62593,0.241895,NO,158,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.116,-3.908,2.792,,0.036,,B,0.22,-0.85,1.344,,69.58,HPB,-1.269,0.361275,0.00341825,0.241895 Ubiquitin_F45D,Ubiquitin_45,Uba1,Ubiquitin,P0CG48,0.241935,NO,45,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.322,-3.965,2.643,4.80693,0.26,E,B,1.62,-0.99,1.531,,53.87,HHH,-1.55267,0.205827,0.000470401,0.241935 Ubiquitin_G76E,Ubiquitin_76,Uba1,Ubiquitin,P0CG48,0.241935,NO,76,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.651,-2.676,1.025,5.7647,0.23,,B,0.12,0.08,9.665,9.665,34.31,OOO,-1.632,0.205827,0.000653872,0.241935 Ubiquitin_K48R,Ubiquitin_48,Uba1,Ubiquitin,P0CG48,0.241935,NO,48,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.436,-2.206,0.77,5.03072,0.132,E,B,2.92,-0.28,1.539,,53.87,OBP,-1.6,0.205827,0.000394633,0.241935 Ubiquitin_R74T,Ubiquitin_74,Uba1,Ubiquitin,P0CG48,0.241935,NO,74,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.739,-2.829,1.09,5.6462,0.838,T,A,0.98,3.15,9.119,9.119,34.31,HBO,-1.71767,0.205827,0.000894236,0.241935 Ubiquitin_V70G,Ubiquitin_70,Uba1,Ubiquitin,P0CG48,0.241935,NO,70,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.874,-2.829,0.955,5.29728,0.05,E,B,0.96,-0.97,2.363,,34.31,HHH,-1.65533,0.205827,0.00106871,0.241935 kka2_1:4_R217I,kka2_1:4_217,Kka2,kka2_1:4,P00552,0.241982,NO,217,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.158,-2.477,1.319,,0.252,T,A,1.2,-0.59,2.074,,52.27,ABH,-1.127,0.168804,0.0047191,0.241982 kka2_1:8_D216N,kka2_1:8_216,Kka2,kka2_1:8,P00552,0.242013,NO,216,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.785,-3.274,2.489,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.100394,0.00229969,0.242013 kka2_1:8_D216N,kka2_1:8_216,Kka2,kka2_1:8,P00552,0.242013,NO,216,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.785,-3.274,2.489,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.100394,0.00229969,0.242013 gb1_A252R,gb1_252,gb1,gb1,P06654,0.242023,NO,252,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.175,-3.443,2.268,,,,,,,,,,PHA,-1.55967,0.177985,0.00125598,0.242023 gb1_A260W,gb1_260,gb1,gb1,P06654,0.242023,NO,260,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.486,-5.127,3.641,,,,,,,0.173,,9.6,HHP,-1.70967,0.177985,0.0055808,0.242023 gb1_T270P,gb1_270,gb1,gb1,P06654,0.242023,NO,270,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-3.15,-3.713,0.563,,,,,,,1.326,,45.54,HPH,-1.843,0.177985,0.00223707,0.242023 gb1_T279P,gb1_279,gb1,gb1,P06654,0.242023,NO,279,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.32,-3.604,2.284,,,,,,,0.529,,35.71,HPH,-1.50067,0.177985,0.00421454,0.242023 gb1_V265W,gb1_265,gb1,gb1,P06654,0.242023,NO,265,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.843,-5.098,3.255,,,,,,,0.402,,11.83,OHA,-1.64567,0.177985,0.00360613,0.242023 gb1_Y229E,gb1_229,gb1,gb1,P06654,0.242023,NO,229,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-1.282,-3.4,2.118,,,,,,,,,,PHB,-1.4915,0.177985,0.00366605,0.242023 gb1_Y271D,gb1_271,gb1,gb1,P06654,0.242023,NO,271,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-1.181,-3.696,2.515,,,,,,,,,,PHA,-1.92933,0.177985,0.00236544,0.242023 beta-lactamase_2500_Y262E,beta-lactamase_2500_262,TEM-1,beta-lactamase_2500,P62593,0.242098,NO,262,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.361275,0.00853516,0.242098 beta-lactamase_M67K,beta-lactamase_67,TEM-1,beta-lactamase,P62593,0.242136,NO,67,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-2.231,-3.7,1.469,4.9618,0.006,G,P,1.07,-0.81,1.463,,65.03,HHP,-1.502,0.221079,0.00409753,0.242136 beta-lactamase_2500_L218K,beta-lactamase_2500_218,TEM-1,beta-lactamase_2500,P62593,0.242174,NO,218,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.391,-2.186,0.795,,,I,b,0.55,-0.53,9.151,9.151,74.48,OHH,-1.58867,0.361275,0.00618274,0.242174 beta-lactamase_156_N130F,beta-lactamase_156_130,TEM-1,beta-lactamase_156,P62593,0.242245,NO,130,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-0.798,-4.292,3.494,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.111618,0.000683376,0.242245 beta-lactamase_2500_P65V,beta-lactamase_2500_65,TEM-1,beta-lactamase_2500,P62593,0.242251,NO,65,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.894,-3.39,2.496,,0.098,E,B,0.52,-0.62,0.3,,40.56,HOH,-1.03233,0.361275,0.00152776,0.242251 E1_Ubiquitin_G75A,E1_Ubiquitin_75,Uba1,E1_Ubiquitin,P0CG63,0.242263,NO,75,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.999,-2.773,1.774,,0.552,T,A,0.75,0.9,4.369,,83.73,BOO,-1.1,0.18783,0.00153276,0.242263 kka2_1:4_A34D,kka2_1:4_34,Kka2,kka2_1:4,P00552,0.24227,NO,34,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.928,-3.625,2.697,,0.417,.,B,0.46,2.29,0.262,,52.27,AHH,-1.747,0.168804,0.00343484,0.24227 kka2_1:4_A119Q,kka2_1:4_119,Kka2,kka2_1:4,P00552,0.242272,NO,119,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.073,-4.017,2.944,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.168804,0.00441074,0.242272 kka2_1:2_L102F,kka2_1:2_102,Kka2,kka2_1:2,P00552,0.242294,NO,102,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.804,-3.669,2.865,,,T,A,1.59,-1.17,4.258,,42.42,AHH,-1.398,0.295029,0.00201332,0.242294 kka2_1:1_D261L,kka2_1:1_261,Kka2,kka2_1:1,P00552,0.242375,NO,261,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.708,-3.836,3.128,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.520039,0.0224846,0.242375 kka2_1:4_V185G,kka2_1:4_185,Kka2,kka2_1:4,P00552,0.242444,NO,185,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.045,-3.615,2.57,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.168804,0.00367031,0.242444 beta-lactamase_S240P,beta-lactamase_240,TEM-1,beta-lactamase,P62593,0.242454,NO,240,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.537,-3.804,2.267,4.75024,,,B,0.74,-0.74,0.357,,65.38,OPB,-1.263,0.221079,0.00591201,0.242454 kka2_1:1_Y244G,kka2_1:1_244,Kka2,kka2_1:1,P00552,0.2426,NO,244,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-0.775,-3.611,2.836,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.520039,0.00453187,0.2426 kka2_1:2_L174E,kka2_1:2_174,Kka2,kka2_1:2,P00552,0.242623,NO,174,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.952,-3.9,2.948,,,H,A,1.59,-0.31,8.521,,51.89,BHB,-2.08533,0.295029,0.00438501,0.242623 kka2_1:1_W236M,kka2_1:1_236,Kka2,kka2_1:1,P00552,0.242626,NO,236,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-1.363,-4.508,3.145,,0.303,H,A,1.51,-0.76,12.263,12.263,48.48,AHH,-1.81267,0.520039,0.0088796,0.242626 kka2_1:1_R202W,kka2_1:1_202,Kka2,kka2_1:1,P00552,0.242646,NO,202,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.761,-5.54,3.779,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.520039,0.00696498,0.242646 beta-lactamase_625_R59P,beta-lactamase_625_59,TEM-1,beta-lactamase_625,P62593,0.24267,NO,59,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.345,-3.961,2.616,,0.329,S,L,1.2,-0.09,2.995,,73.08,HBO,-2.24267,0.213352,0.00318082,0.24267 kka2_1:4_Y257G,kka2_1:4_257,Kka2,kka2_1:4,P00552,0.242724,NO,257,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-1.064,-3.67,2.606,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.168804,0.0148191,0.242724 beta-lactamase_2500_N168W,beta-lactamase_2500_168,TEM-1,beta-lactamase_2500,P62593,0.242746,NO,168,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-1.029,-5.48,4.451,,0.113,G,A,0.61,-0.4,2.9,,44.41,HPA,-1.13233,0.361275,0.00288667,0.242746 kka2_1:4_D159I,kka2_1:4_159,Kka2,kka2_1:4,P00552,0.242813,NO,159,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.82,-4.102,3.282,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.168804,0.0030485,0.242813 kka2_1:2_D220N,kka2_1:2_220,Kka2,kka2_1:2,P00552,0.242885,NO,220,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.787,-3.336,2.549,,,H,A,0.75,-1.14,0.745,,46.59,PAH,-1.152,0.295029,0.00158066,0.242885 kka2_1:4_V36Q,kka2_1:4_36,Kka2,kka2_1:4,P00552,0.242922,NO,36,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-0.898,-4.235,3.337,,0.292,E,B,0.44,0.21,0.278,,52.27,HHH,-1.484,0.168804,0.00245633,0.242922 kka2_1:2_I115W,kka2_1:2_115,Kka2,kka2_1:2,P00552,0.24295,NO,115,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.606,-5.354,3.748,,0.105,H,A,0.48,-1.18,0.878,,65.53,PHH,-2.205,0.295029,0.00836567,0.24295 kka2_1:2_L184N,kka2_1:2_184,Kka2,kka2_1:2,P00552,0.242977,NO,184,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.496,-4.154,2.658,,0.489,E,B,0.55,-0.06,14.044,14.044,63.26,AHH,-1.24833,0.295029,0.00518742,0.242977 beta-lactamase_625_S128T,beta-lactamase_625_128,TEM-1,beta-lactamase_625,P62593,0.242991,NO,128,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-0.84,-2.971,2.131,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.213352,0.00071483,0.242991 kka2_1:4_T225P,kka2_1:4_225,Kka2,kka2_1:4,P00552,0.242995,NO,225,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.393,-4.067,1.674,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.168804,0.0113598,0.242995 Pab1_F170V,Pab1_170,Pab1,Pab1,P04147,0.243101,NO,170,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.269,-3.174,1.905,,0.331,E,B,0.87,-1.31,2.061,,79.72,OHH,-1.06367,0.175299,0.000540225,0.243101 kka2_1:1_A79C,kka2_1:1_79,Kka2,kka2_1:1,P00552,0.243126,NO,79,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.368,-5.212,2.844,,0.563,.,B,0.46,-0.43,7.792,7.792,71.59,HHH,-1.752,0.520039,0.00664821,0.243126 kka2_1:1_I221G,kka2_1:1_221,Kka2,kka2_1:1,P00552,0.243192,NO,221,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.739,-3.884,2.145,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.520039,0.00945908,0.243192 kka2_1:4_H135E,kka2_1:4_135,Kka2,kka2_1:4,P00552,0.24323,NO,135,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-1.331,-3.297,1.966,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.168804,0.00532566,0.24323 kka2_1:1_P179H,kka2_1:1_179,Kka2,kka2_1:1,P00552,0.243232,NO,179,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.974,-4.803,3.829,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.520039,0.00298346,0.243232 beta-lactamase_39_A132P,beta-lactamase_39_132,TEM-1,beta-lactamase_39,P62593,0.243253,NO,132,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.9,-3.725,2.825,,,H,A,0.46,-0.93,8.408,,64.69,PHH,-1.138,0.0495842,0.000962524,0.243253 beta-lactamase_D155C,beta-lactamase_155,TEM-1,beta-lactamase,P62593,0.243282,NO,155,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.889,-5.157,4.268,4.92265,0.049,,B,0.45,-0.9,3.208,,64.69,OAB,-1.62267,0.221079,0.00135315,0.243282 kka2_1:8_V153E,kka2_1:8_153,Kka2,kka2_1:8,P00552,0.243332,NO,153,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.092,-3.813,2.721,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.100394,0.00501119,0.243332 kka2_1:8_V153E,kka2_1:8_153,Kka2,kka2_1:8,P00552,0.243332,NO,153,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.092,-3.813,2.721,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.100394,0.00501119,0.243332 beta-lactamase_2500_A34E,beta-lactamase_2500_34,TEM-1,beta-lactamase_2500,P62593,0.243337,NO,34,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.059,-3.743,1.684,,,H,A,0.46,-0.54,2.921,,73.78,AHA,-1.74967,0.361275,0.00407913,0.243337 beta-lactamase_625_E164W,beta-lactamase_625_164,TEM-1,beta-lactamase_625,P62593,0.243393,NO,164,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-0.948,-5.346,4.398,,0.011,T,B,1.04,-0.4,1.321,,64.69,HAO,-1.388,0.213352,0.00137286,0.243393 beta-lactamase_156_T107E,beta-lactamase_156_107,TEM-1,beta-lactamase_156,P62593,0.243429,NO,107,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.117,-3.43,2.313,,,G,A,0.22,-0.06,0.341,,67.83,HPA,-1.265,0.111618,0.00239347,0.243429 beta-lactamase_625_F64A,beta-lactamase_625_64,TEM-1,beta-lactamase_625,P62593,0.243476,NO,64,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-0.841,-3.303,2.462,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.213352,0.000947691,0.243476 kka2_1:4_L212N,kka2_1:4_212,Kka2,kka2_1:4,P00552,0.24348,NO,212,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.904,-4.173,3.269,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.168804,0.0031426,0.24348 beta-lactamase_2500_L100G,beta-lactamase_2500_100,TEM-1,beta-lactamase_2500,P62593,0.243509,NO,100,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.218,-3.854,2.636,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.361275,0.00413885,0.243509 hsp90_M589G,hsp90_589,hsp90,hsp90,P02829,0.243542,NO,589,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-3.858,-2.511,0,4.72723,0.032,H,A,0.84,0.31,,,,PHA,-3.24233,0.368192,0.000222939,0.243542 beta-lactamase_2500_D231F,beta-lactamase_2500_231,TEM-1,beta-lactamase_2500,P62593,0.24366,NO,231,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.816,-4.318,3.502,,,E,B,0.75,-1.06,0.319,,65.38,HAB,-0.994,0.361275,0.00107395,0.24366 beta-lactamase_625_P65I,beta-lactamase_625_65,TEM-1,beta-lactamase_625,P62593,0.243777,NO,65,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.894,-3.716,2.822,,0.098,E,B,0.52,-0.62,0.3,,40.56,HOH,-1.03233,0.213352,0.00152776,0.243777 beta-lactamase_625_S128M,beta-lactamase_625_128,TEM-1,beta-lactamase_625,P62593,0.243854,NO,128,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-0.84,-4.48,3.64,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.213352,0.00071483,0.243854 beta-lactamase_156_Y262D,beta-lactamase_156_262,TEM-1,beta-lactamase_156,P62593,0.243859,NO,262,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.111618,0.00853516,0.243859 kka2_1:2_G210N,kka2_1:2_210,Kka2,kka2_1:2,P00552,0.243871,NO,210,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.095,-3.653,2.558,,0.103,T,A,0.29,-0.62,0.271,,50,OOB,-0.966667,0.295029,0.00598378,0.243871 kka2_1:4_F206A,kka2_1:4_206,Kka2,kka2_1:4,P00552,0.243871,NO,206,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.349,-3.367,2.018,,0.006,E,B,0.58,-1.21,1.342,,63.64,OHH,-1.04,0.168804,0.00936868,0.243871 kka2_1:1_V185Y,kka2_1:1_185,Kka2,kka2_1:1,P00552,0.243935,NO,185,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.045,-4.096,3.051,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.520039,0.00367031,0.243935 kka2_1:1_D216R,kka2_1:1_216,Kka2,kka2_1:1,P00552,0.24398,NO,216,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.785,-3.929,3.144,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.520039,0.00229969,0.24398 kka2_1:1_V16F,kka2_1:1_16,Kka2,kka2_1:1,P00552,0.243981,NO,16,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-3.087,-4.39,1.303,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.520039,0.00694011,0.243981 beta-lactamase_39_S128P,beta-lactamase_39_128,TEM-1,beta-lactamase_39,P62593,0.244082,NO,128,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-0.84,-3.655,2.815,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.0495842,0.00071483,0.244082 kka2_1:8_C192W,kka2_1:8_192,Kka2,kka2_1:8,P00552,0.244155,NO,192,C,W,CW,Special,Hydrophobic,5.07,5.89,0.82,215,121,204,83,108.5,227.8,119.3,-1.067,-5.111,4.044,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.100394,0.00485428,0.244155 kka2_1:8_C192W,kka2_1:8_192,Kka2,kka2_1:8,P00552,0.244155,NO,192,C,W,CW,Special,Hydrophobic,5.07,5.89,0.82,215,121,204,83,108.5,227.8,119.3,-1.067,-5.111,4.044,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.100394,0.00485428,0.244155 beta-lactamase_625_S68T,beta-lactamase_625_68,TEM-1,beta-lactamase_625,P62593,0.244251,NO,68,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-0.913,-3.02,2.107,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.213352,0.000800065,0.244251 kka2_1:2_C77H,kka2_1:2_77,Kka2,kka2_1:2,P00552,0.244257,NO,77,C,H,CH,Special,PositiveCharge,5.07,7.59,2.52,174,121,155,34,108.5,153.2,44.7,-1.477,-4.937,3.46,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.295029,0.00441216,0.244257 kka2_1:2_R253I,kka2_1:2_253,Kka2,kka2_1:2,P00552,0.244304,NO,253,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.356,-4.056,2.7,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.295029,0.0144195,0.244304 kka2_1:8_F264Q,kka2_1:8_264,Kka2,kka2_1:8,P00552,0.244319,NO,264,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.02,-4.325,3.305,,0.296,,?,1.62,0.02,1.553,,71.59,HHO,-0.9655,0.100394,,0.244319 kka2_1:8_F264Q,kka2_1:8_264,Kka2,kka2_1:8,P00552,0.244319,NO,264,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.02,-4.325,3.305,,0.296,,?,1.62,0.02,1.553,,71.59,HHO,-0.9655,0.100394,,0.244319 beta-lactamase_D177E,beta-lactamase_177,TEM-1,beta-lactamase,P62593,0.244321,NO,177,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.967,-2.98,2.013,5.08038,0.006,T,L,1.59,-1.02,3.536,,64.69,BAP,-0.873667,0.221079,0.000864022,0.244321 beta-lactamase_2500_Y95R,beta-lactamase_2500_95,TEM-1,beta-lactamase_2500,P62593,0.244335,NO,95,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-1.715,-4.186,2.471,,0.122,,b,0.21,-0.37,2.914,,77.62,BHP,-2.16167,0.361275,0.00479449,0.244335 beta-lactamase_39_N130K,beta-lactamase_39_130,TEM-1,beta-lactamase_39,P62593,0.244347,NO,130,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-0.798,-3.232,2.434,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.0495842,0.000683376,0.244347 kka2_1:2_V153N,kka2_1:2_153,Kka2,kka2_1:2,P00552,0.244349,NO,153,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.092,-4.209,3.117,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.295029,0.00501119,0.244349 beta-lactamase_T262Q,beta-lactamase_262,TEM-1,beta-lactamase,P62593,0.244445,NO,262,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.332,-3.885,2.553,5.06002,0.108,E,B,0.3,-0.55,1.423,,67.83,PPO,-2.081,0.221079,0.00853516,0.244445 kka2_1:2_G210E,kka2_1:2_210,Kka2,kka2_1:2,P00552,0.244447,NO,210,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.095,-3.693,2.598,,0.103,T,A,0.29,-0.62,0.271,,50,OOB,-0.966667,0.295029,0.00598378,0.244447 kka2_1:2_A255I,kka2_1:2_255,Kka2,kka2_1:2,P00552,0.244448,NO,255,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.715,-4.011,2.296,,0.466,H,A,0.46,-0.52,5.144,,65.53,HHH,-1.71267,0.295029,0.0126809,0.244448 kka2_1:2_H162V,kka2_1:2_162,Kka2,kka2_1:2,P00552,0.244448,NO,162,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-2.319,-3.881,1.562,,0.071,G,A,0.17,1.01,3.187,,64.39,ABP,-2.02067,0.295029,0.00616145,0.244448 kka2_1:4_I196N,kka2_1:4_196,Kka2,kka2_1:4,P00552,0.244496,NO,196,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-2.115,-4.284,2.169,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.168804,0.0107273,0.244496 beta-lactamase_2500_L188K,beta-lactamase_2500_188,TEM-1,beta-lactamase_2500,P62593,0.244517,NO,188,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.166,-3.695,2.529,,,H,A,0.55,-0.3,17.865,17.865,60.14,PHB,-1.47033,0.361275,0.00295687,0.244517 beta-lactamase_2500_T187E,beta-lactamase_2500_187,TEM-1,beta-lactamase_2500,P62593,0.244521,NO,187,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.401,-3.52,2.119,,0.007,H,A,0.22,-1.19,3.91,,67.48,PPH,-1.69633,0.361275,0.00491782,0.244521 beta-lactamase_2500_T187P,beta-lactamase_2500_187,TEM-1,beta-lactamase_2500,P62593,0.244534,NO,187,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.401,-3.906,2.505,,0.007,H,A,0.22,-1.19,3.91,,67.48,PPH,-1.69633,0.361275,0.00491782,0.244534 kka2_1:2_A117N,kka2_1:2_117,Kka2,kka2_1:2,P00552,0.244645,NO,117,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.828,-3.99,3.162,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.295029,0.00282984,0.244645 beta-lactamase_625_D174W,beta-lactamase_625_174,TEM-1,beta-lactamase_625,P62593,0.244695,NO,174,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.738,-5.547,4.809,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.213352,0.00125633,0.244695 beta-lactamase_625_V259H,beta-lactamase_625_259,TEM-1,beta-lactamase_625,P62593,0.244734,NO,259,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.213352,0.0070773,0.244734 beta-lactamase_156_G240V,beta-lactamase_156_240,TEM-1,beta-lactamase_156,P62593,0.244756,NO,240,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.111618,0.00591201,0.244756 kka2_1:1_D208F,kka2_1:1_208,Kka2,kka2_1:1,P00552,0.244757,NO,208,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.708,-4.32,3.612,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.520039,0.00212588,0.244757 kka2_1:1_A144M,kka2_1:1_144,Kka2,kka2_1:1,P00552,0.244768,NO,144,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.859,-4.454,3.595,,,H,A,0.46,0.21,0.842,,52.65,BHB,-1.72933,0.520039,0.00231095,0.244768 beta-lactamase_2500_D174I,beta-lactamase_2500_174,TEM-1,beta-lactamase_2500,P62593,0.244815,NO,174,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.738,-4.01,3.272,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.361275,0.00125633,0.244815 beta-lactamase_2500_L167H,beta-lactamase_2500_167,TEM-1,beta-lactamase_2500,P62593,0.244922,NO,167,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.138,-4.852,3.714,,0.015,G,A,0.55,-0.63,7.813,,64.69,AHP,-1.30767,0.361275,0.00303566,0.244922 beta-lactamase_A15R,beta-lactamase_15,TEM-1,beta-lactamase,P62593,0.245057,NO,15,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.654,-2.741,1.087,,,,,,,31.998,31.998,93.01,HHH,-2.10833,0.221079,0.00248966,0.245057 beta-lactamase_N272F,beta-lactamase_272,TEM-1,beta-lactamase,P62593,0.245072,NO,272,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-1.127,-4.367,3.24,5.37826,0.081,H,A,0.09,-0.97,1.468,,63.64,BPB,-1.56333,0.221079,0.00545371,0.245072 kka2_1:1_P167H,kka2_1:1_167,Kka2,kka2_1:1,P00552,0.245117,NO,167,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-2.403,-4.915,2.512,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.520039,0.00543203,0.245117 beta-lactamase_2500_A278P,beta-lactamase_2500_278,TEM-1,beta-lactamase_2500,P62593,0.245128,NO,278,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.361275,0.0310297,0.245128 beta-lactamase_2500_G141P,beta-lactamase_2500_141,TEM-1,beta-lactamase_2500,P62593,0.245151,NO,141,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.828,-3.881,3.053,,0.575,T,l,0.29,-0.28,1.493,,64.69,HOO,-1.08933,0.361275,0.0012419,0.245151 hsp90_G584I,hsp90_584,hsp90,hsp90,P02829,0.245158,NO,584,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-2.511,-2.939,0,5.20094,0.414,S,b,0.84,0.33,,,,HOH,-3.32733,0.368192,0.000222939,0.245158 beta-lactamase_625_L219Y,beta-lactamase_625_219,TEM-1,beta-lactamase_625,P62593,0.245331,NO,219,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.313,-3.958,2.645,,,I,A,0.55,-0.51,5.627,,74.48,HHB,-1.21533,0.213352,0.00664345,0.245331 kka2_1:2_A215T,kka2_1:2_215,Kka2,kka2_1:2,P00552,0.245373,NO,215,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.968,-2.586,1.618,,0.039,E,B,0.46,-0.59,2.137,,50.38,HHA,-1.00467,0.295029,0.00529129,0.245373 kka2_1:1_P179E,kka2_1:1_179,Kka2,kka2_1:1,P00552,0.245403,NO,179,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.974,-3.589,2.615,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.520039,0.00298346,0.245403 kka2_1:1_P179K,kka2_1:1_179,Kka2,kka2_1:1,P00552,0.245403,NO,179,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.974,-3.58,2.606,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.520039,0.00298346,0.245403 kka2_1:1_V113G,kka2_1:1_113,Kka2,kka2_1:1,P00552,0.245437,NO,113,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.233,-3.759,2.526,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.520039,0.00650191,0.245437 kka2_1:8_R226Q,kka2_1:8_226,Kka2,kka2_1:8,P00552,0.245466,NO,226,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.392,-2.994,1.602,,0.222,H,A,0.16,-0.71,3.818,,56.06,PBA,-1.84767,0.100394,0.0108032,0.245466 kka2_1:8_R226Q,kka2_1:8_226,Kka2,kka2_1:8,P00552,0.245466,NO,226,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.392,-2.994,1.602,,0.222,H,A,0.16,-0.71,3.818,,56.06,PBA,-1.84767,0.100394,0.0108032,0.245466 kka2_1:1_V36H,kka2_1:1_36,Kka2,kka2_1:1,P00552,0.24549,NO,36,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-0.898,-4.978,4.08,,0.292,E,B,0.44,0.21,0.278,,52.27,HHH,-1.484,0.520039,0.00245633,0.24549 beta-lactamase_2500_F64W,beta-lactamase_2500_64,TEM-1,beta-lactamase_2500,P62593,0.245495,NO,64,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-0.841,-4.422,3.581,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.361275,0.000947691,0.245495 beta-lactamase_625_G234Y,beta-lactamase_625_234,TEM-1,beta-lactamase_625,P62593,0.245496,NO,234,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.62,-4.387,3.767,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.213352,0.000889577,0.245496 kka2_1:1_L107H,kka2_1:1_107,Kka2,kka2_1:1,P00552,0.245515,NO,107,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.238,-4.994,3.756,,0.197,.,B,0.55,-1.1,3.542,,71.59,BHH,-2.143,0.520039,0.00561937,0.245515 kka2_1:1_A137T,kka2_1:1_137,Kka2,kka2_1:1,P00552,0.245527,NO,137,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.156,-3.52,1.364,,0.029,H,A,0.46,0.34,1.323,,63.26,PHB,-2.559,0.520039,0.00515054,0.245527 beta-lactamase_2500_T178G,beta-lactamase_2500_178,TEM-1,beta-lactamase_2500,P62593,0.24554,NO,178,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-0.791,-3.358,2.567,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.361275,0.000684366,0.24554 kka2_1:1_Y257P,kka2_1:1_257,Kka2,kka2_1:1,P00552,0.245611,NO,257,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-1.064,-4.26,3.196,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.520039,0.0148191,0.245611 kka2_1:1_A215G,kka2_1:1_215,Kka2,kka2_1:1,P00552,0.245633,NO,215,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.968,-3.05,2.082,,0.039,E,B,0.46,-0.59,0.754,,50.38,HHA,-1.00467,0.520039,0.00529129,0.245633 kka2_1:2_D33F,kka2_1:2_33,Kka2,kka2_1:2,P00552,0.245686,NO,33,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.186,-4.506,2.32,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.295029,0.00633568,0.245686 kka2_1:2_C192H,kka2_1:2_192,Kka2,kka2_1:2,P00552,0.245697,NO,192,C,H,CH,Special,PositiveCharge,5.07,7.59,2.52,174,121,155,34,108.5,153.2,44.7,-1.067,-4.779,3.712,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.295029,0.00485428,0.245697 beta-lactamase_625_M67Y,beta-lactamase_625_67,TEM-1,beta-lactamase_625,P62593,0.245718,NO,67,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-2.231,-4.282,2.051,,0.006,G,P,0.55,-0.81,2.653,,65.03,HHP,-1.502,0.213352,0.00409753,0.245718 beta-lactamase_625_S68F,beta-lactamase_625_68,TEM-1,beta-lactamase_625,P62593,0.245732,NO,68,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-0.913,-4.116,3.203,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.213352,0.000800065,0.245732 hsp90_G584V,hsp90_584,hsp90,hsp90,P02829,0.245763,NO,584,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-2.511,-2.682,0,5.20094,0.414,S,b,0.84,0.33,,,,HOH,-3.32733,0.368192,0.000222939,0.245763 kka2_1:8_D227W,kka2_1:8_227,Kka2,kka2_1:8,P00552,0.245793,NO,227,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.758,-5.454,3.696,,0.128,H,A,0.75,-0.63,0.281,,56.06,BAH,-1.43067,0.100394,0.00745029,0.245793 kka2_1:8_D227W,kka2_1:8_227,Kka2,kka2_1:8,P00552,0.245793,NO,227,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.758,-5.454,3.696,,0.128,H,A,0.75,-0.63,0.281,,56.06,BAH,-1.43067,0.100394,0.00745029,0.245793 kka2_1:1_H188E,kka2_1:1_188,Kka2,kka2_1:1,P00552,0.245796,NO,188,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-0.913,-3.211,2.298,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.520039,0.00273139,0.245796 beta-lactamase_L146E,beta-lactamase_146,TEM-1,beta-lactamase,P62593,0.245907,NO,146,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.462,-3.93,2.468,5.62483,0.007,H,A,1.3,-0.56,1.953,,64.69,AHP,-1.656,0.221079,0.00474542,0.245907 kka2_1:2_C192K,kka2_1:2_192,Kka2,kka2_1:2,P00552,0.245952,NO,192,C,K,CK,Special,PositiveCharge,5.07,9.74,4.67,202,121,146,25,108.5,168.6,60.1,-1.067,-3.841,2.774,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.295029,0.00485428,0.245952 kka2_1:8_V186D,kka2_1:8_186,Kka2,kka2_1:8,P00552,0.245956,NO,186,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.011,-4.046,3.035,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.100394,0.00409703,0.245956 kka2_1:8_V186D,kka2_1:8_186,Kka2,kka2_1:8,P00552,0.245956,NO,186,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.011,-4.046,3.035,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.100394,0.00409703,0.245956 kka2_1:1_L19I,kka2_1:1_19,Kka2,kka2_1:1,P00552,0.246002,NO,19,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.254,-2.338,1.084,,0.08,T,A,0.55,-0.26,17.165,17.165,65.53,BHH,-2.221,0.520039,0.00620703,0.246002 kka2_1:1_G74H,kka2_1:1_74,Kka2,kka2_1:1,P00552,0.246005,NO,74,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.18,-4.623,3.443,,0.621,T,l,0.75,0.2,15.356,15.356,64.39,POH,-1.91667,0.520039,0.00587035,0.246005 beta-lactamase_F14E,beta-lactamase_14,TEM-1,beta-lactamase,P62593,0.246074,NO,14,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-2.736,-3.813,1.077,,,,,,,1.537,,93.01,HHH,-2.26133,0.221079,0.00277095,0.246074 beta-lactamase_A230R,beta-lactamase_230,TEM-1,beta-lactamase,P62593,0.24616,NO,230,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.154,-3.858,2.704,4.54336,0.01,E,B,0.75,-1.17,1.97,,50,HHA,-1.079,0.221079,0.00516841,0.24616 kka2_1:2_E231P,kka2_1:2_231,Kka2,kka2_1:2,P00552,0.246188,NO,231,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.002,-3.957,1.955,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.295029,0.00732383,0.246188 kka2_1:4_R217E,kka2_1:4_217,Kka2,kka2_1:4,P00552,0.246219,NO,217,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.158,-3.44,2.282,,0.252,T,A,1.2,-0.59,2.074,,52.27,ABH,-1.127,0.168804,0.0047191,0.246219 kka2_1:2_A222M,kka2_1:2_222,Kka2,kka2_1:2,P00552,0.246229,NO,222,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.725,-4.508,3.783,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.295029,0.00207657,0.246229 beta-lactamase_2500_L79S,beta-lactamase_2500_79,TEM-1,beta-lactamase_2500,P62593,0.246236,NO,79,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.842,-3.608,2.766,,0.007,H,A,0.55,-0.16,0.823,,50.35,HHP,-1.44333,0.361275,0.000947397,0.246236 kka2_1:8_A224Q,kka2_1:8_224,Kka2,kka2_1:8,P00552,0.246283,NO,224,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.977,-4.028,3.051,,,H,A,0.46,-1.26,0.357,,63.64,HHP,-1.41033,0.100394,0.00352047,0.246283 kka2_1:8_A224Q,kka2_1:8_224,Kka2,kka2_1:8,P00552,0.246283,NO,224,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.977,-4.028,3.051,,,H,A,0.46,-1.26,0.357,,63.64,HHP,-1.41033,0.100394,0.00352047,0.246283 kka2_1:8_M116W,kka2_1:8_116,Kka2,kka2_1:8,P00552,0.246283,NO,116,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-2.482,-5.227,2.745,,,H,A,1.59,-0.88,4.659,,71.59,HHH,-1.63867,0.100394,0.00745147,0.246283 kka2_1:8_M116W,kka2_1:8_116,Kka2,kka2_1:8,P00552,0.246283,NO,116,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-2.482,-5.227,2.745,,,H,A,1.59,-0.88,4.659,,71.59,HHH,-1.63867,0.100394,0.00745147,0.246283 kka2_1:1_D154M,kka2_1:1_154,Kka2,kka2_1:1,P00552,0.246288,NO,154,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.876,-4.959,4.083,,0.457,.,b,0.75,1.48,0.658,,52.65,HAP,-1.52467,0.520039,0.00292633,0.246288 kka2_1:4_C209S,kka2_1:4_209,Kka2,kka2_1:4,P00552,0.246302,NO,209,C,S,CS,Special,Polar,5.07,5.68,0.61,112,121,105,-16,108.5,89,-19.5,-0.906,-3.458,2.552,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.168804,0.00260862,0.246302 kka2_1:2_F203K,kka2_1:2_203,Kka2,kka2_1:2,P00552,0.246329,NO,203,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-0.911,-3.934,3.023,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.295029,0.00318738,0.246329 beta-lactamase_156_S128Q,beta-lactamase_156_128,TEM-1,beta-lactamase_156,P62593,0.246405,NO,128,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-0.84,-3.674,2.834,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.111618,0.00071483,0.246405 beta-lactamase_156_I280R,beta-lactamase_156_280,TEM-1,beta-lactamase_156,P62593,0.246412,NO,280,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.111618,0.0530888,0.246412 beta-lactamase_2500_W288E,beta-lactamase_2500_288,TEM-1,beta-lactamase_2500,P62593,0.246543,NO,288,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,,,,,,,,,,,,,BHO,,0.361275,,0.246543 beta-lactamase_2500_L223H,beta-lactamase_2500_223,TEM-1,beta-lactamase_2500,P62593,0.246582,NO,223,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.055,-4.894,3.839,,0.27,,B,0.55,0.09,1.334,,74.48,HHO,-1.35033,0.361275,0.00372793,0.246582 kka2_1:2_F133Q,kka2_1:2_133,Kka2,kka2_1:2,P00552,0.2466,NO,133,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-0.871,-4.345,3.474,,0.178,.,B,0.58,0.43,1.999,,42.42,OHA,-0.871667,0.295029,0.00182168,0.2466 beta-lactamase_L191G,beta-lactamase_191,TEM-1,beta-lactamase,P62593,0.246649,NO,191,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.087,-3.655,2.568,5.72226,,H,A,1.07,0.09,1.23,,63.29,BHH,-1.445,0.221079,0.00263549,0.246649 beta-lactamase_156_A132K,beta-lactamase_156_132,TEM-1,beta-lactamase_156,P62593,0.246665,NO,132,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.9,-3.501,2.601,,,H,A,0.46,-0.93,10.621,,64.69,PHH,-1.138,0.111618,0.000962524,0.246665 beta-lactamase_625_L284K,beta-lactamase_625_284,TEM-1,beta-lactamase_625,P62593,0.246684,NO,284,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.981,-3.504,1.523,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.213352,0.0686156,0.246684 kka2_1:4_C131S,kka2_1:4_131,Kka2,kka2_1:4,P00552,0.246736,NO,131,C,S,CS,Special,Polar,5.07,5.68,0.61,112,121,105,-16,108.5,89,-19.5,-0.831,-3.414,2.583,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.168804,0.00170814,0.246736 kka2_1:8_R258V,kka2_1:8_258,Kka2,kka2_1:8,P00552,0.246772,NO,258,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.626,-3.61,1.984,,0.316,H,A,0.16,-0.85,5.58,,53.03,HBH,-1.25933,0.100394,0.00983174,0.246772 kka2_1:8_R258V,kka2_1:8_258,Kka2,kka2_1:8,P00552,0.246772,NO,258,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.626,-3.61,1.984,,0.316,H,A,0.16,-0.85,5.58,,53.03,HBH,-1.25933,0.100394,0.00983174,0.246772 kka2_1:2_R66T,kka2_1:2_66,Kka2,kka2_1:2,P00552,0.246774,NO,66,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-0.922,-3.484,2.562,,0.103,H,A,1.2,-0.2,2.659,,46.21,HBH,-1.13567,0.295029,0.00161025,0.246774 beta-lactamase_39_V259D,beta-lactamase_39_259,TEM-1,beta-lactamase_39,P62593,0.246783,NO,259,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.0495842,0.0070773,0.246783 beta-lactamase_156_A230E,beta-lactamase_156_230,TEM-1,beta-lactamase_156,P62593,0.246791,NO,230,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.154,-3.566,2.412,,0.01,E,B,0.46,-1.17,2.179,,50,HHA,-1.079,0.111618,0.00516841,0.246791 kka2_1:1_R147T,kka2_1:1_147,Kka2,kka2_1:1,P00552,0.246804,NO,147,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.123,-3.56,2.437,,0.094,H,A,1.2,0.97,2.578,,64.02,PBH,-1.98267,0.520039,0.00549168,0.246804 kka2_1:1_V75D,kka2_1:1_75,Kka2,kka2_1:1,P00552,0.24684,NO,75,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-2.06,-4.066,2.006,,0.042,.,B,0.44,-0.2,2.815,,71.59,OHO,-1.563,0.520039,0.00693733,0.24684 beta-lactamase_M184G,beta-lactamase_184,TEM-1,beta-lactamase,P62593,0.246867,NO,184,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.593,-3.601,2.008,5.39575,,H,A,1.3,-0.87,2.893,,62.94,HHH,-1.41,0.221079,0.00356019,0.246867 beta-lactamase_2500_W208I,beta-lactamase_2500_208,TEM-1,beta-lactamase_2500,P62593,0.246891,NO,208,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-0.818,-4.01,3.192,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.361275,0.00126609,0.246891 beta-lactamase_156_I261G,beta-lactamase_156_261,TEM-1,beta-lactamase_156,P62593,0.246916,NO,261,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.111618,0.0123091,0.246916 beta-lactamase_39_F70P,beta-lactamase_39_70,TEM-1,beta-lactamase_39,P62593,0.246917,NO,70,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.169,-4.211,3.042,,,H,A,0.58,-1.34,1.14,,63.99,PHB,-0.980667,0.0495842,0.00193499,0.246917 kka2_1:1_D23F,kka2_1:1_23,Kka2,kka2_1:1,P00552,0.246918,NO,23,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.459,-4.448,1.989,,0.695,E,B,0.75,-0.65,2.655,,65.53,HAH,-1.94033,0.520039,0.007195,0.246918 kka2_1:1_E142W,kka2_1:1_142,Kka2,kka2_1:1,P00552,0.246926,NO,142,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.221,-5.578,3.357,,0.471,H,A,1.52,0.85,3.626,,65.53,HAB,-2.08033,0.520039,0.00748883,0.246926 beta-lactamase_2500_L160E,beta-lactamase_2500_160,TEM-1,beta-lactamase_2500,P62593,0.247003,NO,160,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.977,-3.906,2.929,,0.022,,B,0.55,-0.6,0.895,,44.41,BHA,-0.936,0.361275,0.00193775,0.247003 beta-lactamase_2500_S201I,beta-lactamase_2500_201,TEM-1,beta-lactamase_2500,P62593,0.247045,NO,201,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.183,-3.765,2.582,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.361275,0.00198815,0.247045 kka2_1:1_D183E,kka2_1:1_183,Kka2,kka2_1:1,P00552,0.247052,NO,183,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.204,-2.074,0.87,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.520039,0.00426304,0.247052 kka2_1:1_D183W,kka2_1:1_183,Kka2,kka2_1:1,P00552,0.247052,NO,183,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.204,-5.594,4.39,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.520039,0.00426304,0.247052 kka2_1:1_F263T,kka2_1:1_263,Kka2,kka2_1:1,P00552,0.247084,NO,263,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-0.911,-3.673,2.762,,0.006,G,A,0.58,-0.12,2.284,,45.83,AHH,-0.92,0.520039,0.0172454,0.247084 kka2_1:1_L259Y,kka2_1:1_259,Kka2,kka2_1:1,P00552,0.247133,NO,259,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.088,-4.087,2.999,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.520039,0.0206964,0.247133 kka2_1:4_L126S,kka2_1:4_126,Kka2,kka2_1:4,P00552,0.247146,NO,126,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.246,-3.666,2.42,,0.285,S,B,0.55,0.12,0.302,,51.89,PHA,-1.744,0.168804,0.0066485,0.247146 beta-lactamase_625_G236W,beta-lactamase_625_236,TEM-1,beta-lactamase_625,P62593,0.247221,NO,236,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.784,-5.189,4.405,,0.241,,b,0.29,-0.59,3.506,,64.69,HOO,-1.025,0.213352,0.00162372,0.247221 beta-lactamase_625_V42G,beta-lactamase_625_42,TEM-1,beta-lactamase_625,P62593,0.247289,NO,42,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.564,-2.773,1.209,,0.017,E,B,0.44,-0.51,2.576,,63.99,BHO,-1.042,0.213352,0.00404515,0.247289 beta-lactamase_2500_V78H,beta-lactamase_2500_78,TEM-1,beta-lactamase_2500,P62593,0.247385,NO,78,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.459,-5.015,3.556,,,H,A,0.44,-0.47,31.376,31.376,63.64,HHH,-1.17833,0.361275,0.00492501,0.247385 kka2_1:4_P194F,kka2_1:4_194,Kka2,kka2_1:4,P00552,0.24739,NO,194,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.846,-4.517,3.671,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.168804,0.00314194,0.24739 beta-lactamase_625_G281P,beta-lactamase_625_281,TEM-1,beta-lactamase_625,P62593,0.247435,NO,281,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.213352,0.0406482,0.247435 beta-lactamase_2500_G142Q,beta-lactamase_2500_142,TEM-1,beta-lactamase_2500,P62593,0.247437,NO,142,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.707,-4.087,3.38,,0.034,,p,0.29,-0.64,1.883,,64.69,OOO,-0.834,0.361275,0.00060149,0.247437 kka2_1:1_D134E,kka2_1:1_134,Kka2,kka2_1:1,P00552,0.247441,NO,134,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.969,-2.461,1.492,,0.421,B,B,0.75,0.31,2.329,,49.62,HAB,-1.057,0.520039,0.00270812,0.247441 kka2_1:1_I141K,kka2_1:1_141,Kka2,kka2_1:1,P00552,0.247456,NO,141,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.495,-3.912,2.417,,0.068,H,A,0.48,-0.01,7.546,7.546,92.05,BHA,-1.689,0.520039,0.00744745,0.247456 kka2_1:2_D62M,kka2_1:2_62,Kka2,kka2_1:2,P00552,0.2475,NO,62,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.591,-4.884,3.293,,0.262,H,A,0.75,0.08,10.048,10.048,64.39,PAA,-1.77833,0.295029,0.00744243,0.2475 kka2_1:1_P249W,kka2_1:1_249,Kka2,kka2_1:1,P00552,0.247546,NO,249,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.867,-5.488,3.621,,0.406,.,B,0.52,-0.01,8.037,8.037,92.05,HOA,-1.66867,0.520039,0.011045,0.247546 beta-lactamase_39_I277R,beta-lactamase_39_277,TEM-1,beta-lactamase_39,P62593,0.247549,NO,277,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.0495842,0.0169305,0.247549 E1_Ubiquitin_G75N,E1_Ubiquitin_75,Uba1,E1_Ubiquitin,P0CG63,0.247569,NO,75,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.999,-3.318,2.319,,0.552,T,A,0.75,0.9,4.369,,83.73,BOO,-1.1,0.18783,0.00153276,0.247569 kka2_1:8_D208F,kka2_1:8_208,Kka2,kka2_1:8,P00552,0.247586,NO,208,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.708,-4.32,3.612,,0.36,,l,0.29,-1.01,,,,HAO,-0.929667,0.100394,0.00212588,0.247586 kka2_1:8_D208F,kka2_1:8_208,Kka2,kka2_1:8,P00552,0.247586,NO,208,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.708,-4.32,3.612,,0.36,,l,0.29,-1.01,,,,HAO,-0.929667,0.100394,0.00212588,0.247586 kka2_1:2_F206T,kka2_1:2_206,Kka2,kka2_1:2,P00552,0.247668,NO,206,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.349,-3.71,2.361,,0.006,E,B,0.58,-1.21,0.978,,63.64,OHH,-1.04,0.295029,0.00936868,0.247668 kka2_1:1_S40P,kka2_1:1_40,Kka2,kka2_1:1,P00552,0.247697,NO,40,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.645,-3.224,0.579,,0.32,E,B,0.27,-0.9,25.997,25.997,71.59,HPH,-1.91567,0.520039,0.00693477,0.247697 beta-lactamase_2500_I277H,beta-lactamase_2500_277,TEM-1,beta-lactamase_2500,P62593,0.247739,NO,277,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.361275,0.0169305,0.247739 beta-lactamase_2500_V42R,beta-lactamase_2500_42,TEM-1,beta-lactamase_2500,P62593,0.247743,NO,42,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.564,-4.138,2.574,,0.017,E,B,0.44,-0.51,1.86,,63.99,BHO,-1.042,0.361275,0.00404515,0.247743 kka2_1:8_G210H,kka2_1:8_210,Kka2,kka2_1:8,P00552,0.247748,NO,210,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.095,-4.794,3.699,,0.103,T,A,0.75,-0.62,2.687,,50,OOB,-0.966667,0.100394,0.00598378,0.247748 kka2_1:8_G210H,kka2_1:8_210,Kka2,kka2_1:8,P00552,0.247748,NO,210,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.095,-4.794,3.699,,0.103,T,A,0.75,-0.62,2.687,,50,OOB,-0.966667,0.100394,0.00598378,0.247748 kka2_1:2_V198K,kka2_1:2_198,Kka2,kka2_1:2,P00552,0.247798,NO,198,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.719,-3.652,1.933,,0.05,E,B,1.48,-0.95,1.074,,56.06,HHA,-1.88667,0.295029,0.00835002,0.247798 kka2_1:2_I207E,kka2_1:2_207,Kka2,kka2_1:2,P00552,0.24782,NO,207,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.175,-3.934,2.759,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.295029,0.00611824,0.24782 kka2_1:4_L102E,kka2_1:4_102,Kka2,kka2_1:4,P00552,0.24787,NO,102,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.804,-3.916,3.112,,,T,A,0.55,-1.17,0.65,,42.42,AHH,-1.398,0.168804,0.00201332,0.24787 kka2_1:8_Y244G,kka2_1:8_244,Kka2,kka2_1:8,P00552,0.24791,NO,244,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-0.775,-3.611,2.836,,0.066,H,A,1.25,-0.64,,,,HHO,-1.41267,0.100394,0.00453187,0.24791 kka2_1:8_Y244G,kka2_1:8_244,Kka2,kka2_1:8,P00552,0.24791,NO,244,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-0.775,-3.611,2.836,,0.066,H,A,1.25,-0.64,,,,HHO,-1.41267,0.100394,0.00453187,0.24791 kka2_1:2_Y257W,kka2_1:2_257,Kka2,kka2_1:2,P00552,0.247914,NO,257,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-1.064,-4.353,3.289,,0.022,H,A,0.21,-0.88,0.833,,52.65,HHB,-1.39333,0.295029,0.0148191,0.247914 beta-lactamase_156_I277R,beta-lactamase_156_277,TEM-1,beta-lactamase_156,P62593,0.247929,NO,277,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.111618,0.0169305,0.247929 kka2_1:1_T72Y,kka2_1:1_72,Kka2,kka2_1:1,P00552,0.247969,NO,72,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.38,-4.457,2.077,,0.784,H,A,0.22,0.29,10.43,10.43,65.53,HPP,-2.238,0.520039,0.00750756,0.247969 beta-lactamase_2500_S233H,beta-lactamase_2500_233,TEM-1,beta-lactamase_2500,P62593,0.248,NO,233,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.886,-4.67,2.784,,0.016,E,B,0.27,-1.01,2.851,,77.62,BPO,-1.17267,0.361275,0.00311415,0.248 kka2_1:1_G210N,kka2_1:1_210,Kka2,kka2_1:1,P00552,0.248056,NO,210,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.095,-3.653,2.558,,0.103,T,A,0.29,-0.62,14.483,14.483,50,OOB,-0.966667,0.520039,0.00598378,0.248056 beta-lactamase_625_L136G,beta-lactamase_625_136,TEM-1,beta-lactamase_625,P62593,0.248068,NO,136,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.232,-3.856,2.624,,,H,A,0.55,-0.34,0.336,,48.95,HHH,-1.088,0.213352,0.00442304,0.248068 kka2_1:8_D261P,kka2_1:8_261,Kka2,kka2_1:8,P00552,0.248073,NO,261,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.708,-3.683,2.975,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.100394,0.0224846,0.248073 kka2_1:8_D261P,kka2_1:8_261,Kka2,kka2_1:8,P00552,0.248073,NO,261,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.708,-3.683,2.975,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.100394,0.0224846,0.248073 beta-lactamase_2500_Y95D,beta-lactamase_2500_95,TEM-1,beta-lactamase_2500,P62593,0.24808,NO,95,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-1.715,-4.078,2.363,,0.122,,b,0.21,-0.37,2.914,,77.62,BHP,-2.16167,0.361275,0.00479449,0.24808 beta-lactamase_2500_I261E,beta-lactamase_2500_261,TEM-1,beta-lactamase_2500,P62593,0.24809,NO,261,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.361275,0.0123091,0.24809 kka2_1:2_F206K,kka2_1:2_206,Kka2,kka2_1:2,P00552,0.248133,NO,206,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.349,-3.906,2.557,,0.006,E,B,0.58,-1.21,0.978,,63.64,OHH,-1.04,0.295029,0.00936868,0.248133 kka2_1:2_D227G,kka2_1:2_227,Kka2,kka2_1:2,P00552,0.248142,NO,227,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.758,-3.04,1.282,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.295029,0.00745029,0.248142 beta-lactamase_625_S233K,beta-lactamase_625_233,TEM-1,beta-lactamase_625,P62593,0.248187,NO,233,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.886,-3.496,1.61,,0.016,E,B,0.27,-1.01,1.773,,77.62,BPO,-1.17267,0.213352,0.00311415,0.248187 kka2_1:1_A215T,kka2_1:1_215,Kka2,kka2_1:1,P00552,0.248201,NO,215,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.968,-2.586,1.618,,0.039,E,B,0.46,-0.59,0.754,,50.38,HHA,-1.00467,0.520039,0.00529129,0.248201 kka2_1:4_D208L,kka2_1:4_208,Kka2,kka2_1:4,P00552,0.248236,NO,208,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.708,-3.836,3.128,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.168804,0.00212588,0.248236 beta-lactamase_156_E164T,beta-lactamase_156_164,TEM-1,beta-lactamase_156,P62593,0.248273,NO,164,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-0.948,-3.491,2.543,,0.011,T,B,1.04,-0.4,3.445,,64.69,HAO,-1.388,0.111618,0.00137286,0.248273 kka2_1:2_G99Y,kka2_1:2_99,Kka2,kka2_1:2,P00552,0.248303,NO,99,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.596,-4.416,3.82,,0.368,S,g,0.29,-0.87,,,,OOP,-1.63067,0.295029,0.00186055,0.248303 kka2_1:2_D101K,kka2_1:2_101,Kka2,kka2_1:2,P00552,0.248306,NO,101,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.028,-3.563,2.535,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.295029,0.00423361,0.248306 kka2_1:1_D134S,kka2_1:1_134,Kka2,kka2_1:1,P00552,0.248311,NO,134,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.969,-2.62,1.651,,0.421,B,B,0.75,0.31,2.329,,49.62,HAB,-1.057,0.520039,0.00270812,0.248311 kka2_1:1_T146Y,kka2_1:1_146,Kka2,kka2_1:1,P00552,0.248311,NO,146,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.978,-4.381,1.403,,0.281,H,A,0.82,0.78,2.105,,92.05,BPB,-1.96833,0.520039,0.00606474,0.248311 beta-lactamase_2500_L136H,beta-lactamase_2500_136,TEM-1,beta-lactamase_2500,P62593,0.248345,NO,136,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.232,-4.999,3.767,,,H,A,0.55,-0.34,1.36,,48.95,HHH,-1.088,0.361275,0.00442304,0.248345 hsp90_N588D,hsp90_588,hsp90,hsp90,P02829,0.248362,NO,588,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-3.051,-2.847,0,4.61142,0.019,H,A,0.14,0.39,,,,HPH,-3.12167,0.368192,0.000222939,0.248362 kka2_1:1_L212E,kka2_1:1_212,Kka2,kka2_1:1,P00552,0.248363,NO,212,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.904,-3.881,2.977,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.520039,0.0031426,0.248363 kka2_1:1_G151I,kka2_1:1_151,Kka2,kka2_1:1,P00552,0.248465,NO,151,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.873,-4.249,3.376,,0.678,T,l,0.29,1.36,0.226,,49.62,HOH,-1.11433,0.520039,0.00339918,0.248465 kka2_1:1_S54K,kka2_1:1_54,Kka2,kka2_1:1,P00552,0.248478,NO,54,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.471,-3.67,1.199,,0.408,S,b,0.27,1.01,6.085,,71.59,HPO,-2.259,0.520039,0.00782867,0.248478 kka2_1:2_L184E,kka2_1:2_184,Kka2,kka2_1:2,P00552,0.248482,NO,184,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.496,-3.868,2.372,,0.489,E,B,0.55,-0.06,14.044,14.044,63.26,AHH,-1.24833,0.295029,0.00518742,0.248482 kka2_1:1_V97P,kka2_1:1_97,Kka2,kka2_1:1,P00552,0.248487,NO,97,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.453,-4.137,2.684,,0.083,,B,1.48,-0.83,13.576,13.576,53.03,AHO,-1.85067,0.520039,0.00737869,0.248487 beta-lactamase_L74N,beta-lactamase_74,TEM-1,beta-lactamase,P62593,0.248518,NO,74,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.296,-4.114,2.818,5.50288,,H,A,1.75,-0.91,1.581,,50,HHO,-1.34933,0.221079,0.00493255,0.248518 hsp90_G584P,hsp90_584,hsp90,hsp90,P02829,0.248519,NO,584,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-2.511,-3.033,0,5.20094,0.414,S,b,0.84,0.33,,,,HOH,-3.32733,0.368192,0.000222939,0.248519 kka2_1:8_Y257V,kka2_1:8_257,Kka2,kka2_1:8,P00552,0.248559,NO,257,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-1.064,-3.391,2.327,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.100394,0.0148191,0.248559 kka2_1:8_Y257V,kka2_1:8_257,Kka2,kka2_1:8,P00552,0.248559,NO,257,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-1.064,-3.391,2.327,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.100394,0.0148191,0.248559 kka2_1:4_N200I,kka2_1:4_200,Kka2,kka2_1:4,P00552,0.248612,NO,200,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-2.446,-4.261,1.815,,0.756,T,L,0.61,-0.08,1.746,,64.39,APO,-2.08,0.168804,0.00838549,0.248612 beta-lactamase_625_T131E,beta-lactamase_625_131,TEM-1,beta-lactamase_625,P62593,0.248653,NO,131,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.328,-3.523,2.195,,,H,A,0.22,-0.69,2.031,,67.48,PPH,-1.00867,0.213352,0.00345886,0.248653 beta-lactamase_2500_V101P,beta-lactamase_2500_101,TEM-1,beta-lactamase_2500,P62593,0.248705,NO,101,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.295,-4.04,2.745,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.361275,0.00374492,0.248705 PSD95pdz3_G324Y,PSD95pdz3_324,PSD95pdz3,PSD95pdz3,P31016,0.248705,NO,324,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.008,-4.069,3.061,4.98881,,,,,10.4525,,,,HOH,-1.293,0.0758425,0.00103462,0.248705 beta-lactamase_156_A278P,beta-lactamase_156_278,TEM-1,beta-lactamase_156,P62593,0.248721,NO,278,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.111618,0.0310297,0.248721 kka2_1:2_I221H,kka2_1:2_221,Kka2,kka2_1:2,P00552,0.248749,NO,221,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.739,-5.027,3.288,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.295029,0.00945908,0.248749 beta-lactamase_2500_L167P,beta-lactamase_2500_167,TEM-1,beta-lactamase_2500,P62593,0.248773,NO,167,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.138,-4.076,2.938,,0.015,G,A,0.55,-0.63,7.813,,64.69,AHP,-1.30767,0.361275,0.00303566,0.248773 kka2_1:2_L126F,kka2_1:2_126,Kka2,kka2_1:2,P00552,0.248813,NO,126,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.246,-3.893,2.647,,0.285,S,B,0.55,0.12,1.392,,51.89,PHA,-1.744,0.295029,0.0066485,0.248813 kka2_1:2_R217P,kka2_1:2_217,Kka2,kka2_1:2,P00552,0.248815,NO,217,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.158,-2.617,1.459,,0.252,T,A,1.2,-0.59,0.381,,52.27,ABH,-1.127,0.295029,0.0047191,0.248815 beta-lactamase_39_I277D,beta-lactamase_39_277,TEM-1,beta-lactamase_39,P62593,0.248847,NO,277,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.0495842,0.0169305,0.248847 kka2_1:2_I228H,kka2_1:2_228,Kka2,kka2_1:2,P00552,0.248889,NO,228,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.142,-5.006,3.864,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.295029,0.00458834,0.248889 beta-lactamase_2500_S104M,beta-lactamase_2500_104,TEM-1,beta-lactamase_2500,P62593,0.248903,NO,104,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.015,-4.54,3.525,,0.04,,b,0.27,0.57,1.133,,63.29,HPO,-1.05267,0.361275,0.00218083,0.248903 beta-lactamase_156_I277E,beta-lactamase_156_277,TEM-1,beta-lactamase_156,P62593,0.24891,NO,277,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.869,-4.006,2.137,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.111618,0.0169305,0.24891 beta-lactamase_2500_I125S,beta-lactamase_2500_125,TEM-1,beta-lactamase_2500,P62593,0.248932,NO,125,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.441,-2.843,1.402,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.361275,0.00383964,0.248932 kka2_1:1_F240N,kka2_1:1_240,Kka2,kka2_1:1,P00552,0.248954,NO,240,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-0.911,-4.185,3.274,,,H,A,1.62,-1.21,5.798,,50.38,BHH,-1.67267,0.520039,0.00552543,0.248954 beta-lactamase_625_V259N,beta-lactamase_625_259,TEM-1,beta-lactamase_625,P62593,0.24896,NO,259,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.213352,0.0070773,0.24896 kka2_1:8_G201I,kka2_1:8_201,Kka2,kka2_1:8,P00552,0.249045,NO,201,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.56,-4.262,2.702,,0.149,T,l,0.75,-0.57,2.152,,52.65,POB,-1.92233,0.100394,0.00820117,0.249045 kka2_1:8_G201I,kka2_1:8_201,Kka2,kka2_1:8,P00552,0.249045,NO,201,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.56,-4.262,2.702,,0.149,T,l,0.75,-0.57,2.152,,52.65,POB,-1.92233,0.100394,0.00820117,0.249045 kka2_1:2_A144Y,kka2_1:2_144,Kka2,kka2_1:2,P00552,0.249158,NO,144,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.859,-4.19,3.331,,,H,A,0.46,0.21,6.844,,52.65,BHB,-1.72933,0.295029,0.00231095,0.249158 kka2_1:4_V49H,kka2_1:4_49,Kka2,kka2_1:4,P00552,0.249245,NO,49,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.614,-5.018,3.404,,,E,B,0.44,-0.77,1.233,,64.39,HHB,-1.3,0.168804,0.00615685,0.249245 hsp90_A587T,hsp90_587,hsp90,hsp90,P02829,0.249255,NO,587,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.456,-2.8,0,4.91216,0.049,H,A,0.55,-0.02,,,,PHP,-2.757,0.368192,0.000222939,0.249255 kka2_1:1_N200R,kka2_1:1_200,Kka2,kka2_1:1,P00552,0.24929,NO,200,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-2.446,-3.001,0.555,,0.756,T,L,0.61,-0.08,17.299,17.299,64.39,APO,-2.08,0.520039,0.00838549,0.24929 beta-lactamase_2500_Y103K,beta-lactamase_2500_103,TEM-1,beta-lactamase_2500,P62593,0.249336,NO,103,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-1.33,-3.666,2.336,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.361275,0.00443048,0.249336 kka2_1:1_D52K,kka2_1:1_52,Kka2,kka2_1:1,P00552,0.249449,NO,52,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.271,-3.096,0.825,,0.22,E,B,0.75,0.8,2.64,,71.59,PAH,-2.38367,0.520039,0.00175694,0.249449 beta-lactamase_156_M184W,beta-lactamase_156_184,TEM-1,beta-lactamase_156,P62593,0.249467,NO,184,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.593,-5.149,3.556,,,H,A,0.55,-0.87,1.671,,62.94,HHH,-1.41,0.111618,0.00356019,0.249467 beta-lactamase_2500_N274C,beta-lactamase_2500_274,TEM-1,beta-lactamase_2500,P62593,0.249487,NO,274,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.361275,0.0110418,0.249487 kka2_1:1_P45F,kka2_1:1_45,Kka2,kka2_1:1,P00552,0.2495,NO,45,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.774,-4.506,2.732,,0.669,.,B,0.52,-0.76,4.882,,71.59,BOH,-2.152,0.520039,0.00590481,0.2495 kka2_1:1_A78C,kka2_1:1_78,Kka2,kka2_1:1,P00552,0.249534,NO,78,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.744,-4.918,3.174,,0.078,.,B,0.46,-0.53,0.206,,56.06,OHH,-1.863,0.520039,0.00457299,0.249534 beta-lactamase_625_R162F,beta-lactamase_625_162,TEM-1,beta-lactamase_625,P62593,0.249535,NO,162,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.016,-4.266,3.25,,0.124,S,B,1.2,-0.37,1.445,,64.69,ABH,-1.25,0.213352,0.000561334,0.249535 beta-lactamase_2500_T264P,beta-lactamase_2500_264,TEM-1,beta-lactamase_2500,P62593,0.249543,NO,264,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.361275,0.0119399,0.249543 kka2_1:1_Q4Y,kka2_1:1_4,Kka2,kka2_1:1,P00552,0.249593,NO,4,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.361,-4.04,1.679,,,,,,,5.615,,71.59,APA,-1.95533,0.520039,0.00239179,0.249593 beta-lactamase_G142P,beta-lactamase_142,TEM-1,beta-lactamase,P62593,0.249628,NO,142,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.707,-3.877,3.17,4.55474,0.034,,p,0.77,-0.64,1.947,,64.69,OOO,-0.834,0.221079,0.00060149,0.249628 kka2_1:2_D62I,kka2_1:2_62,Kka2,kka2_1:2,P00552,0.249638,NO,62,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.591,-4.096,2.505,,0.262,H,A,0.75,0.08,10.048,10.048,64.39,PAA,-1.77833,0.295029,0.00744243,0.249638 beta-lactamase_156_T107K,beta-lactamase_156_107,TEM-1,beta-lactamase_156,P62593,0.249661,NO,107,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.117,-3.447,2.33,,,G,A,0.22,-0.06,0.341,,67.83,HPA,-1.265,0.111618,0.00239347,0.249661 kka2_1:1_D157K,kka2_1:1_157,Kka2,kka2_1:1,P00552,0.249683,NO,157,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.993,-3.506,2.513,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.520039,0.0042313,0.249683 kka2_1:1_Q100Y,kka2_1:1_100,Kka2,kka2_1:1,P00552,0.24969,NO,100,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.77,-4.334,1.564,,0.646,E,B,0.4,-0.79,15.116,15.116,71.59,OPA,-1.46467,0.520039,0.0066405,0.24969 beta-lactamase_2500_P65K,beta-lactamase_2500_65,TEM-1,beta-lactamase_2500,P62593,0.24974,NO,65,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.894,-3.511,2.617,,0.098,E,B,0.52,-0.62,0.3,,40.56,HOH,-1.03233,0.361275,0.00152776,0.24974 beta-lactamase_39_D177H,beta-lactamase_39_177,TEM-1,beta-lactamase_39,P62593,0.249776,NO,177,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.967,-4.511,3.544,,0.006,T,L,0.75,-1.02,3.536,,64.69,BAP,-0.873667,0.0495842,0.000864022,0.249776 beta-lactamase_2500_G142V,beta-lactamase_2500_142,TEM-1,beta-lactamase_2500,P62593,0.249784,NO,142,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.707,-3.751,3.044,,0.034,,p,0.29,-0.64,1.883,,64.69,OOO,-0.834,0.361275,0.00060149,0.249784 kka2_1:1_L107N,kka2_1:1_107,Kka2,kka2_1:1,P00552,0.249792,NO,107,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.238,-4.107,2.869,,0.197,.,B,0.55,-1.1,3.542,,71.59,BHH,-2.143,0.520039,0.00561937,0.249792 kka2_1:8_R226M,kka2_1:8_226,Kka2,kka2_1:8,P00552,0.249853,NO,226,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.392,-4.698,3.306,,0.222,H,A,0.16,-0.71,3.818,,56.06,PBA,-1.84767,0.100394,0.0108032,0.249853 kka2_1:8_R226M,kka2_1:8_226,Kka2,kka2_1:8,P00552,0.249853,NO,226,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.392,-4.698,3.306,,0.222,H,A,0.16,-0.71,3.818,,56.06,PBA,-1.84767,0.100394,0.0108032,0.249853 kka2_1:8_R38N,kka2_1:8_38,Kka2,kka2_1:8,P00552,0.249853,NO,38,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.207,-3.763,2.556,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.100394,0.00372499,0.249853 kka2_1:8_R38N,kka2_1:8_38,Kka2,kka2_1:8,P00552,0.249853,NO,38,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.207,-3.763,2.556,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.100394,0.00372499,0.249853 beta-lactamase_2500_N134H,beta-lactamase_2500_134,TEM-1,beta-lactamase_2500,P62593,0.249867,NO,134,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-0.879,-4.073,3.194,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.361275,0.000644786,0.249867 kka2_1:2_E111Y,kka2_1:2_111,Kka2,kka2_1:2,P00552,0.249888,NO,111,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.28,-4.387,2.107,,0.155,H,A,1.52,-1.14,2.792,,65.53,HAB,-2.27833,0.295029,0.00746789,0.249888 kka2_1:1_I228C,kka2_1:1_228,Kka2,kka2_1:1,P00552,0.249911,NO,228,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.142,-4.738,3.596,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.520039,0.00458834,0.249911 PSD95pdz3_N326P,PSD95pdz3_326,PSD95pdz3,PSD95pdz3,P31016,0.249952,NO,326,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-1.41,-3.561,2.151,5.52537,,,,,19.0688,,,,HPH,-1.52133,0.0758425,0.00101078,0.249952 beta-lactamase_156_S68C,beta-lactamase_156_68,TEM-1,beta-lactamase_156,P62593,0.249966,NO,68,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-0.913,-4.705,3.792,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.111618,0.000800065,0.249966 beta-lactamase_625_L137D,beta-lactamase_625_137,TEM-1,beta-lactamase_625,P62593,0.249974,NO,137,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.03,-4.128,3.098,,,H,A,0.55,-0.38,1.5,,42.31,HHP,-1.58933,0.213352,0.00278599,0.249974 kka2_1:1_S105E,kka2_1:1_105,Kka2,kka2_1:1,P00552,0.249995,NO,105,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.945,-2.784,0.839,,0.056,S,B,0.27,-1.04,3.442,,65.53,PPB,-2.17033,0.520039,0.00847233,0.249995 beta-lactamase_2500_G142I,beta-lactamase_2500_142,TEM-1,beta-lactamase_2500,P62593,0.249996,NO,142,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.707,-4.199,3.492,,0.034,,p,0.29,-0.64,1.883,,64.69,OOO,-0.834,0.361275,0.00060149,0.249996 Ubiquitin_I36R,Ubiquitin_36,Uba1,Ubiquitin,P0CG48,0.25,NO,36,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.477,-4.018,2.541,5.1035,0.203,,B,0.27,-0.22,1.552,,30.8,OHO,-1.30767,0.205827,0.000630555,0.25 Ubiquitin_I44F,Ubiquitin_44,Uba1,Ubiquitin,P0CG48,0.25,NO,44,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.566,-2.848,1.282,4.71256,,E,B,0.27,-1.17,5.26,,39.71,HHH,-1.38567,0.205827,0.000613305,0.25 Ubiquitin_I44T,Ubiquitin_44,Uba1,Ubiquitin,P0CG48,0.25,NO,44,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.566,-3.445,1.879,4.71256,,E,B,0.27,-1.17,5.26,,39.71,HHH,-1.38567,0.205827,0.000613305,0.25 Ubiquitin_K48M,Ubiquitin_48,Uba1,Ubiquitin,P0CG48,0.25,NO,48,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.436,-4.559,3.123,5.03072,0.132,E,B,2.92,-0.28,1.539,,53.87,OBP,-1.6,0.205827,0.000394633,0.25 Ubiquitin_K48P,Ubiquitin_48,Uba1,Ubiquitin,P0CG48,0.25,NO,48,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.436,-3.828,2.392,5.03072,0.132,E,B,2.92,-0.28,1.539,,53.87,OBP,-1.6,0.205827,0.000394633,0.25 Ubiquitin_K48V,Ubiquitin_48,Uba1,Ubiquitin,P0CG48,0.25,NO,48,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.436,-3.493,2.057,5.03072,0.132,E,B,2.92,-0.28,1.539,,53.87,OBP,-1.6,0.205827,0.000394633,0.25 Ubiquitin_K48Y,Ubiquitin_48,Uba1,Ubiquitin,P0CG48,0.25,NO,48,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.436,-4.109,2.673,5.03072,0.132,E,B,2.92,-0.28,1.539,,53.87,OBP,-1.6,0.205827,0.000394633,0.25 Ubiquitin_R72L,Ubiquitin_72,Uba1,Ubiquitin,P0CG48,0.25,NO,72,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.034,-3.409,1.375,5.19484,0.077,,B,1.41,-0.1,9.638,9.638,42.77,HBH,-1.82733,0.205827,0.000768249,0.25 Ubiquitin_T12F,Ubiquitin_12,Uba1,Ubiquitin,P0CG48,0.25,NO,12,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.288,-4.031,2.743,4.93973,0.417,E,B,0.8,0.12,2.762,,25.84,BPH,-1.39867,0.205827,0.000657544,0.25 Ubiquitin_T9Y,Ubiquitin_9,Uba1,Ubiquitin,P0CG48,0.25,NO,9,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.409,-4.193,2.784,5.24336,0.777,T,A,2.12,-0.12,2.705,,29.93,HPO,-1.50933,0.205827,0.000630716,0.25 Ubiquitin_V17R,Ubiquitin_17,Uba1,Ubiquitin,P0CG48,0.25,NO,17,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.314,-4.101,2.787,5.26282,0.017,,B,2.78,-0.77,3.239,,71.82,AHA,-1.51833,0.205827,0.000659638,0.25 Ubiquitin_V70D,Ubiquitin_70,Uba1,Ubiquitin,P0CG48,0.25,NO,70,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.874,-2.709,0.835,5.29728,0.05,E,B,0.96,-0.97,2.363,,34.31,HHH,-1.65533,0.205827,0.00106871,0.25 beta-lactamase_625_S68M,beta-lactamase_625_68,TEM-1,beta-lactamase_625,P62593,0.25001,NO,68,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-0.913,-4.529,3.616,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.213352,0.000800065,0.25001 kka2_1:2_R211F,kka2_1:2_211,Kka2,kka2_1:2,P00552,0.250021,NO,211,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-0.899,-4.206,3.307,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.295029,0.00204888,0.250021 beta-lactamase_625_T107P,beta-lactamase_625_107,TEM-1,beta-lactamase_625,P62593,0.250027,NO,107,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.117,-3.706,2.589,,,G,A,0.22,-0.06,3.676,,67.83,HPA,-1.265,0.213352,0.00239347,0.250027 beta-lactamase_156_N130W,beta-lactamase_156_130,TEM-1,beta-lactamase_156,P62593,0.250052,NO,130,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-0.798,-5.547,4.749,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.111618,0.000683376,0.250052 beta-lactamase_2500_A123Q,beta-lactamase_2500_123,TEM-1,beta-lactamase_2500,P62593,0.250057,NO,123,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.834,-3.948,3.114,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.361275,0.0010157,0.250057 beta-lactamase_625_D177N,beta-lactamase_625_177,TEM-1,beta-lactamase_625,P62593,0.250112,NO,177,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.967,-2.571,1.604,,0.006,T,L,0.75,-1.02,1.333,,64.69,BAP,-0.873667,0.213352,0.000864022,0.250112 beta-lactamase_156_F64H,beta-lactamase_156_64,TEM-1,beta-lactamase_156,P62593,0.250223,NO,64,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-0.841,-4.455,3.614,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.111618,0.000947691,0.250223 kka2_1:2_T225P,kka2_1:2_225,Kka2,kka2_1:2,P00552,0.25024,NO,225,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.393,-4.067,1.674,,0.036,H,A,0.22,-1.22,4.554,,63.64,HPB,-1.58733,0.295029,0.0113598,0.25024 kka2_1:4_V80W,kka2_1:4_80,Kka2,kka2_1:4,P00552,0.250285,NO,80,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.144,-5.458,4.314,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.168804,0.00488211,0.250285 beta-lactamase_156_G240W,beta-lactamase_156_240,TEM-1,beta-lactamase_156,P62593,0.250297,NO,240,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.111618,0.00591201,0.250297 kka2_1:1_R147N,kka2_1:1_147,Kka2,kka2_1:1,P00552,0.250301,NO,147,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.123,-2.501,1.378,,0.094,H,A,1.2,0.97,2.578,,64.02,PBH,-1.98267,0.520039,0.00549168,0.250301 kka2_1:1_Y257S,kka2_1:1_257,Kka2,kka2_1:1,P00552,0.250301,NO,257,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-1.064,-3.698,2.634,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.520039,0.0148191,0.250301 kka2_1:8_L232N,kka2_1:8_232,Kka2,kka2_1:8,P00552,0.250337,NO,232,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.514,-4.176,2.662,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.100394,0.00800103,0.250337 kka2_1:8_L232N,kka2_1:8_232,Kka2,kka2_1:8,P00552,0.250337,NO,232,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.514,-4.176,2.662,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.100394,0.00800103,0.250337 beta-lactamase_625_W288T,beta-lactamase_625_288,TEM-1,beta-lactamase_625,P62593,0.250368,NO,288,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,,,,,,,,,,,,,BHO,,0.213352,,0.250368 beta-lactamase_625_T158I,beta-lactamase_625_158,TEM-1,beta-lactamase_625,P62593,0.250426,NO,158,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.116,-3.731,2.615,,0.036,,B,0.22,-0.85,3.771,,69.58,HPB,-1.269,0.213352,0.00341825,0.250426 beta-lactamase_2500_L136K,beta-lactamase_2500_136,TEM-1,beta-lactamase_2500,P62593,0.250434,NO,136,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.232,-3.824,2.592,,,H,A,0.55,-0.34,1.36,,48.95,HHH,-1.088,0.361275,0.00442304,0.250434 kka2_1:1_R211F,kka2_1:1_211,Kka2,kka2_1:1,P00552,0.250434,NO,211,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-0.899,-4.206,3.307,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.520039,0.00204888,0.250434 kka2_1:2_L19W,kka2_1:2_19,Kka2,kka2_1:2,P00552,0.250482,NO,19,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.254,-5.02,3.766,,0.08,T,A,0.55,-0.26,17.165,17.165,65.53,BHH,-2.221,0.295029,0.00620703,0.250482 WW_domain_W177C,WW_domain_177,Yap65,WW_domain,P46937,0.250483,NO,177,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-1.198,-4.639,3.441,5.18137,,,,,,,,,OHA,-1.197,0.153962,0.00198549,0.250483 kka2_1:8_V97P,kka2_1:8_97,Kka2,kka2_1:8,P00552,0.250498,NO,97,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.453,-4.137,2.684,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.100394,0.00737869,0.250498 kka2_1:8_V97P,kka2_1:8_97,Kka2,kka2_1:8,P00552,0.250498,NO,97,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.453,-4.137,2.684,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.100394,0.00737869,0.250498 kka2_1:1_E262L,kka2_1:1_262,Kka2,kka2_1:1,P00552,0.250521,NO,262,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-0.829,-3.61,2.781,,0.059,G,A,1.04,-0.18,0.837,,42.42,AAH,-0.816,0.520039,0.0191586,0.250521 beta-lactamase_2500_A247H,beta-lactamase_2500_247,TEM-1,beta-lactamase_2500,P62593,0.250531,NO,247,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.361275,0.00611275,0.250531 kka2_1:2_I115R,kka2_1:2_115,Kka2,kka2_1:2,P00552,0.25055,NO,115,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.606,-4.203,2.597,,0.105,H,A,0.48,-1.18,0.878,,65.53,PHH,-2.205,0.295029,0.00836567,0.25055 beta-lactamase_2500_A235W,beta-lactamase_2500_235,TEM-1,beta-lactamase_2500,P62593,0.250569,NO,235,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.266,-5.379,4.113,,0.32,E,B,0.46,-0.86,0.891,,50,OHO,-0.89,0.361275,0.00493474,0.250569 beta-lactamase_625_L120Y,beta-lactamase_625_120,TEM-1,beta-lactamase_625,P62593,0.250575,NO,120,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.044,-3.856,2.812,,,H,A,0.55,-1.13,7.813,,64.69,AHO,-1.13633,0.213352,0.00143563,0.250575 beta-lactamase_156_L74K,beta-lactamase_156_74,TEM-1,beta-lactamase_156,P62593,0.250587,NO,74,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.296,-3.688,2.392,,,H,A,0.55,-0.91,0.746,,50,HHO,-1.34933,0.111618,0.00493255,0.250587 kka2_1:2_R147F,kka2_1:2_147,Kka2,kka2_1:2,P00552,0.250665,NO,147,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.123,-4.324,3.201,,0.094,H,A,1.2,0.97,0.425,,64.02,PBH,-1.98267,0.295029,0.00549168,0.250665 beta-lactamase_39_K232E,beta-lactamase_39_232,TEM-1,beta-lactamase_39,P62593,0.250672,NO,232,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.012,-3.087,2.075,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.0495842,0.00313441,0.250672 beta-lactamase_2500_I93D,beta-lactamase_2500_93,TEM-1,beta-lactamase_2500,P62593,0.250727,NO,93,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.401,-4.003,2.602,,0.128,E,B,0.48,0.44,19.374,19.374,67.83,BHB,-1.873,0.361275,0.00527066,0.250727 Pab1_N127P,Pab1_127,Pab1,Pab1,P04147,0.250733,NO,127,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-1.079,-3.697,2.618,,0.138,E,B,1.05,-0.51,,,,OPH,-1.13633,0.175299,0.000805159,0.250733 kka2_1:1_L212D,kka2_1:1_212,Kka2,kka2_1:1,P00552,0.250769,NO,212,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.904,-4.134,3.23,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.520039,0.0031426,0.250769 Pab1_N127Y,Pab1_127,Pab1,Pab1,P04147,0.250773,NO,127,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-1.079,-3.98,2.901,,0.138,E,B,1.05,-0.51,,,,OPH,-1.13633,0.175299,0.000805159,0.250773 beta-lactamase_2500_A133N,beta-lactamase_2500_133,TEM-1,beta-lactamase_2500,P62593,0.250802,NO,133,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.186,-3.758,2.572,,,H,A,0.46,-0.86,2.649,,67.83,HHP,-0.988333,0.361275,0.00468022,0.250802 beta-lactamase_156_D177A,beta-lactamase_156_177,TEM-1,beta-lactamase_156,P62593,0.250845,NO,177,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.967,-2.529,1.562,,0.006,T,L,0.75,-1.02,2.072,,64.69,BAP,-0.873667,0.111618,0.000864022,0.250845 kka2_1:1_F171M,kka2_1:1_171,Kka2,kka2_1:1,P00552,0.250935,NO,171,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.326,-4.328,3.002,,0.154,H,A,1.62,-0.1,13.679,13.679,63.64,HHH,-1.45433,0.520039,0.00821426,0.250935 beta-lactamase_625_I245G,beta-lactamase_625_245,TEM-1,beta-lactamase_625,P62593,0.250955,NO,245,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.213352,0.00391032,0.250955 beta-lactamase_625_F64E,beta-lactamase_625_64,TEM-1,beta-lactamase_625,P62593,0.251106,NO,64,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-0.841,-3.89,3.049,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.213352,0.000947691,0.251106 kka2_1:1_R253Y,kka2_1:1_253,Kka2,kka2_1:1,P00552,0.251114,NO,253,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.356,-4.302,2.946,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.520039,0.0144195,0.251114 beta-lactamase_156_C75R,beta-lactamase_156_75,TEM-1,beta-lactamase_156,P62593,0.251175,NO,75,C,R,CR,Special,PositiveCharge,5.07,6.34148,1.27148,180,121,174,53,108.5,173.4,64.9,-1.245,-4.065,2.82,,,H,A,0.46,-0.87,0.876,,50,HOO,-1.24333,0.111618,0.0034616,0.251175 kka2_1:1_I207E,kka2_1:1_207,Kka2,kka2_1:1,P00552,0.251215,NO,207,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.175,-3.934,2.759,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.520039,0.00611824,0.251215 kka2_1:8_Y22I,kka2_1:8_22,Kka2,kka2_1:8,P00552,0.251303,NO,22,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-1.583,-3.083,1.5,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.100394,0.00598977,0.251303 kka2_1:8_Y22I,kka2_1:8_22,Kka2,kka2_1:8,P00552,0.251303,NO,22,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-1.583,-3.083,1.5,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.100394,0.00598977,0.251303 kka2_1:1_D118L,kka2_1:1_118,Kka2,kka2_1:1,P00552,0.251328,NO,118,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.07,-3.589,1.519,,0.61,H,A,0.75,-0.05,13.434,13.434,64.39,HAH,-1.32367,0.520039,0.0067852,0.251328 kka2_1:4_R258D,kka2_1:4_258,Kka2,kka2_1:4,P00552,0.251333,NO,258,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.626,-3.765,2.139,,0.316,H,A,1.2,-0.85,2.655,,53.03,HBH,-1.25933,0.168804,0.00983174,0.251333 beta-lactamase_2500_L284D,beta-lactamase_2500_284,TEM-1,beta-lactamase_2500,P62593,0.25138,NO,284,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.361275,0.0686156,0.25138 beta-lactamase_625_I93G,beta-lactamase_625_93,TEM-1,beta-lactamase_625,P62593,0.251394,NO,93,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.401,-3.805,2.404,,0.128,E,B,0.48,0.44,1.524,,67.83,BHB,-1.873,0.213352,0.00527066,0.251394 beta-lactamase_2500_M209V,beta-lactamase_2500_209,TEM-1,beta-lactamase_2500,P62593,0.251447,NO,209,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.442,-2.446,1.004,,,H,A,0.55,-0.97,3.229,,64.69,HHA,-1.52633,0.361275,0.00625021,0.251447 kka2_1:8_A222P,kka2_1:8_222,Kka2,kka2_1:8,P00552,0.251463,NO,222,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.725,-3.683,2.958,,,H,A,1.04,-1.21,,,,HHH,-1.10833,0.100394,0.00207657,0.251463 kka2_1:8_A222P,kka2_1:8_222,Kka2,kka2_1:8,P00552,0.251463,NO,222,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.725,-3.683,2.958,,,H,A,1.04,-1.21,,,,HHH,-1.10833,0.100394,0.00207657,0.251463 kka2_1:8_L19K,kka2_1:8_19,Kka2,kka2_1:8,P00552,0.251463,NO,19,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.254,-3.899,2.645,,0.08,T,A,1.59,-0.26,2.044,,65.53,BHH,-2.221,0.100394,0.00620703,0.251463 kka2_1:8_L19K,kka2_1:8_19,Kka2,kka2_1:8,P00552,0.251463,NO,19,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.254,-3.899,2.645,,0.08,T,A,1.59,-0.26,2.044,,65.53,BHH,-2.221,0.100394,0.00620703,0.251463 kka2_1:1_W91A,kka2_1:1_91,Kka2,kka2_1:1,P00552,0.251477,NO,91,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-1.178,-3.5,2.322,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.520039,0.00358653,0.251477 kka2_1:4_Y257S,kka2_1:4_257,Kka2,kka2_1:4,P00552,0.251482,NO,257,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-1.064,-3.698,2.634,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.168804,0.0148191,0.251482 kka2_1:1_E231F,kka2_1:1_231,Kka2,kka2_1:1,P00552,0.251519,NO,231,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.002,-4.394,2.392,,0.503,H,A,1.04,-0.23,25.629,25.629,63.26,AAH,-2.06267,0.520039,0.00732383,0.251519 kka2_1:1_E142H,kka2_1:1_142,Kka2,kka2_1:1,P00552,0.251594,NO,142,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.221,-3.221,1,,0.471,H,A,1.52,0.85,3.626,,65.53,HAB,-2.08033,0.520039,0.00748883,0.251594 kka2_1:1_I254G,kka2_1:1_254,Kka2,kka2_1:1,P00552,0.251595,NO,254,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.933,-3.809,1.876,,0.135,H,A,1.52,-0.6,1.859,,71.59,BHH,-1.668,0.520039,0.0132375,0.251595 kka2_1:2_E59Y,kka2_1:2_59,Kka2,kka2_1:2,P00552,0.251617,NO,59,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-0.952,-4.251,3.299,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.295029,0.00280355,0.251617 beta-lactamase_625_T178P,beta-lactamase_625_178,TEM-1,beta-lactamase_625,P62593,0.251646,NO,178,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-0.791,-3.655,2.864,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.213352,0.000684366,0.251646 kka2_1:1_V185I,kka2_1:1_185,Kka2,kka2_1:1,P00552,0.251671,NO,185,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.045,-2.468,1.423,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.520039,0.00367031,0.251671 beta-lactamase_625_T107E,beta-lactamase_625_107,TEM-1,beta-lactamase_625,P62593,0.251701,NO,107,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.117,-3.43,2.313,,,G,A,0.22,-0.06,3.676,,67.83,HPA,-1.265,0.213352,0.00239347,0.251701 kka2_1:1_G99Y,kka2_1:1_99,Kka2,kka2_1:1,P00552,0.251722,NO,99,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.596,-4.416,3.82,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.520039,0.00186055,0.251722 kka2_1:4_Y244P,kka2_1:4_244,Kka2,kka2_1:4,P00552,0.251727,NO,244,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-0.775,-4.133,3.358,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.168804,0.00453187,0.251727 kka2_1:2_F37Q,kka2_1:2_37,Kka2,kka2_1:2,P00552,0.25176,NO,37,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.427,-4.273,2.846,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.295029,0.00586193,0.25176 kka2_1:1_D180C,kka2_1:1_180,Kka2,kka2_1:1,P00552,0.251769,NO,180,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.416,-5.213,2.797,,1.03,S,a,0.75,1.5,1.534,,71.59,OAO,-2.02933,0.520039,0.00756412,0.251769 kka2_1:1_G233P,kka2_1:1_233,Kka2,kka2_1:1,P00552,0.251802,NO,233,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.748,-3.907,3.159,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.520039,0.00232366,0.251802 kka2_1:1_F263P,kka2_1:1_263,Kka2,kka2_1:1,P00552,0.251865,NO,263,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-0.911,-4.356,3.445,,0.006,G,A,0.58,-0.12,2.284,,45.83,AHH,-0.92,0.520039,0.0172454,0.251865 beta-lactamase_39_R159P,beta-lactamase_39_159,TEM-1,beta-lactamase_39,P62593,0.251903,NO,159,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-0.94,-3.905,2.965,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.0495842,0.00108472,0.251903 beta-lactamase_156_S128H,beta-lactamase_156_128,TEM-1,beta-lactamase_156,P62593,0.251975,NO,128,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-0.84,-4.455,3.615,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.111618,0.00071483,0.251975 kka2_1:2_R211A,kka2_1:2_211,Kka2,kka2_1:2,P00552,0.251977,NO,211,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-0.899,-3.167,2.268,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.295029,0.00204888,0.251977 Pab1_K131V,Pab1_131,Pab1,Pab1,P04147,0.251978,NO,131,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.083,-3.346,2.263,,0.462,E,B,1.82,0.57,,,,HBP,-1.12467,0.175299,0.000349395,0.251978 kka2_1:2_R66Y,kka2_1:2_66,Kka2,kka2_1:2,P00552,0.252122,NO,66,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-0.922,-4.225,3.303,,0.103,H,A,1.2,-0.2,2.659,,46.21,HBH,-1.13567,0.295029,0.00161025,0.252122 kka2_1:2_L126S,kka2_1:2_126,Kka2,kka2_1:2,P00552,0.252229,NO,126,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.246,-3.666,2.42,,0.285,S,B,0.55,0.12,1.392,,51.89,PHA,-1.744,0.295029,0.0066485,0.252229 hsp90_A587N,hsp90_587,hsp90,hsp90,P02829,0.252237,NO,587,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.456,-3.051,0,4.91216,0.049,H,A,0.55,-0.02,,,,PHP,-2.757,0.368192,0.000222939,0.252237 kka2_1:1_R258Y,kka2_1:1_258,Kka2,kka2_1:1,P00552,0.252264,NO,258,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.626,-4.283,2.657,,0.316,H,A,1.2,-0.85,7.485,7.485,53.03,HBH,-1.25933,0.520039,0.00983174,0.252264 kka2_1:1_L170S,kka2_1:1_170,Kka2,kka2_1:1,P00552,0.252272,NO,170,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.28,-3.627,2.347,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.520039,0.00730791,0.252272 kka2_1:1_I221K,kka2_1:1_221,Kka2,kka2_1:1,P00552,0.252274,NO,221,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.739,-3.896,2.157,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.520039,0.00945908,0.252274 beta-lactamase_2500_A77P,beta-lactamase_2500_77,TEM-1,beta-lactamase_2500,P62593,0.252282,NO,77,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.234,-3.879,2.645,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.361275,0.00282362,0.252282 kka2_1:4_C209H,kka2_1:4_209,Kka2,kka2_1:4,P00552,0.252283,NO,209,C,H,CH,Special,PositiveCharge,5.07,7.59,2.52,174,121,155,34,108.5,153.2,44.7,-0.906,-4.957,4.051,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.168804,0.00260862,0.252283 beta-lactamase_39_C121W,beta-lactamase_39_121,TEM-1,beta-lactamase_39,P62593,0.252378,NO,121,C,W,CW,Special,Hydrophobic,5.07,5.89,0.82,215,121,204,83,108.5,227.8,119.3,-0.953,-5.146,4.193,,,H,A,0.46,-0.81,7.644,,63.29,HOP,-1.46767,0.0495842,0.000744322,0.252378 kka2_1:2_L174D,kka2_1:2_174,Kka2,kka2_1:2,P00552,0.252384,NO,174,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.952,-4.154,3.202,,,H,A,1.59,-0.31,8.521,,51.89,BHB,-2.08533,0.295029,0.00438501,0.252384 beta-lactamase_156_N274W,beta-lactamase_156_274,TEM-1,beta-lactamase_156,P62593,0.252392,NO,274,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.111618,0.0110418,0.252392 beta-lactamase_2500_E46P,beta-lactamase_2500_46,TEM-1,beta-lactamase_2500,P62593,0.252413,NO,46,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.94,-4.039,2.099,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.361275,0.00427568,0.252413 kka2_1:1_V46W,kka2_1:1_46,Kka2,kka2_1:1,P00552,0.252477,NO,46,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-2.62,-5.568,2.948,,0.192,.,B,0.44,-1.12,20.149,20.149,92.05,OHH,-1.88633,0.520039,0.00631301,0.252477 kka2_1:1_L107R,kka2_1:1_107,Kka2,kka2_1:1,P00552,0.25248,NO,107,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.238,-4.11,2.872,,0.197,.,B,0.55,-1.1,3.542,,71.59,BHH,-2.143,0.520039,0.00561937,0.25248 kka2_1:1_V198T,kka2_1:1_198,Kka2,kka2_1:1,P00552,0.252482,NO,198,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.719,-2.237,0.518,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.520039,0.00835002,0.252482 kka2_1:1_V75R,kka2_1:1_75,Kka2,kka2_1:1,P00552,0.252547,NO,75,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-2.06,-4.101,2.041,,0.042,.,B,0.44,-0.2,2.815,,71.59,OHO,-1.563,0.520039,0.00693733,0.252547 kka2_1:1_A237W,kka2_1:1_237,Kka2,kka2_1:1,P00552,0.252574,NO,237,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.12,-5.457,3.337,,0.068,H,A,0.46,-0.71,2.369,,92.05,HHA,-2.10433,0.520039,0.012257,0.252574 kka2_1:1_L259K,kka2_1:1_259,Kka2,kka2_1:1,P00552,0.252603,NO,259,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.088,-3.716,2.628,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.520039,0.0206964,0.252603 beta-lactamase_2500_K30P,beta-lactamase_2500_30,TEM-1,beta-lactamase_2500,P62593,0.252608,NO,30,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-2.307,-3.871,1.564,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.361275,0.00448593,0.252608 beta-lactamase_625_G243T,beta-lactamase_625_243,TEM-1,beta-lactamase_625,P62593,0.252621,NO,243,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.213352,0.00464034,0.252621 kka2_1:1_I207P,kka2_1:1_207,Kka2,kka2_1:1,P00552,0.252646,NO,207,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.175,-4.149,2.974,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.520039,0.00611824,0.252646 beta-lactamase_156_A124R,beta-lactamase_156_124,TEM-1,beta-lactamase_156,P62593,0.252662,NO,124,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.181,-3.827,2.646,,,H,A,0.46,-0.9,2.027,,64.34,HHH,-1.152,0.111618,0.00481399,0.252662 kka2_1:8_A34D,kka2_1:8_34,Kka2,kka2_1:8,P00552,0.252746,NO,34,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.928,-3.625,2.697,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.100394,0.00343484,0.252746 kka2_1:8_A34D,kka2_1:8_34,Kka2,kka2_1:8,P00552,0.252746,NO,34,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.928,-3.625,2.697,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.100394,0.00343484,0.252746 kka2_1:8_V36Y,kka2_1:8_36,Kka2,kka2_1:8,P00552,0.252746,NO,36,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-0.898,-4.01,3.112,,0.292,E,B,1.48,0.21,0.938,,52.27,HHH,-1.484,0.100394,0.00245633,0.252746 kka2_1:8_V36Y,kka2_1:8_36,Kka2,kka2_1:8,P00552,0.252746,NO,36,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-0.898,-4.01,3.112,,0.292,E,B,1.48,0.21,0.938,,52.27,HHH,-1.484,0.100394,0.00245633,0.252746 kka2_1:2_M148P,kka2_1:2_148,Kka2,kka2_1:2,P00552,0.252749,NO,148,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.847,-4.116,2.269,,0.268,H,A,1.59,0.71,1.439,,64.39,BHA,-1.65467,0.295029,0.00982664,0.252749 kka2_1:1_R66A,kka2_1:1_66,Kka2,kka2_1:1,P00552,0.252754,NO,66,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-0.922,-3.14,2.218,,0.103,H,A,1.2,-0.2,2.659,,46.21,HBH,-1.13567,0.520039,0.00161025,0.252754 kka2_1:1_R66K,kka2_1:1_66,Kka2,kka2_1:1,P00552,0.252754,NO,66,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-0.922,-2.125,1.203,,0.103,H,A,1.2,-0.2,2.659,,46.21,HBH,-1.13567,0.520039,0.00161025,0.252754 E1_Ubiquitin_G75L,E1_Ubiquitin_75,Uba1,E1_Ubiquitin,P0CG63,0.252874,NO,75,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.999,-3.549,2.55,,0.552,T,A,0.75,0.9,4.369,,83.73,BOO,-1.1,0.18783,0.00153276,0.252874 kka2_1:4_A215Y,kka2_1:4_215,Kka2,kka2_1:4,P00552,0.252906,NO,215,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.968,-4.276,3.308,,0.039,E,B,0.46,-0.59,0.754,,50.38,HHA,-1.00467,0.168804,0.00529129,0.252906 kka2_1:1_E96M,kka2_1:1_96,Kka2,kka2_1:1,P00552,0.252929,NO,96,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.573,-4.64,2.067,,0.476,,B,1.52,-0.65,1.254,,71.59,OAH,-2.143,0.520039,0.00369441,0.252929 kka2_1:2_Q219Y,kka2_1:2_219,Kka2,kka2_1:2,P00552,0.252947,NO,219,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-0.93,-4.01,3.08,,0.088,H,A,0.4,-0.85,1.917,,50,HPA,-1.05167,0.295029,0.00237913,0.252947 kka2_1:2_Y22I,kka2_1:2_22,Kka2,kka2_1:2,P00552,0.252952,NO,22,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-1.583,-3.083,1.5,,0.122,.,B,0.21,-0.8,1.838,,65.53,OHA,-1.80333,0.295029,0.00598977,0.252952 kka2_1:1_R217Q,kka2_1:1_217,Kka2,kka2_1:1,P00552,0.252991,NO,217,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.158,-2.901,1.743,,0.252,T,A,1.2,-0.59,0.381,,52.27,ABH,-1.127,0.520039,0.0047191,0.252991 kka2_1:1_I246M,kka2_1:1_246,Kka2,kka2_1:1,P00552,0.25302,NO,246,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-2.008,-2.785,0.777,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.520039,0.0139479,0.25302 kka2_1:8_A144M,kka2_1:8_144,Kka2,kka2_1:8,P00552,0.253065,NO,144,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.859,-4.454,3.595,,,H,A,1.04,0.21,1.118,,52.65,BHB,-1.72933,0.100394,0.00231095,0.253065 kka2_1:8_A144M,kka2_1:8_144,Kka2,kka2_1:8,P00552,0.253065,NO,144,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.859,-4.454,3.595,,,H,A,1.04,0.21,1.118,,52.65,BHB,-1.72933,0.100394,0.00231095,0.253065 beta-lactamase_I93G,beta-lactamase_93,TEM-1,beta-lactamase,P62593,0.253086,NO,93,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.401,-3.805,2.404,5.74695,0.128,E,B,0.77,0.44,1.757,,67.83,BHB,-1.873,0.221079,0.00527066,0.253086 Pab1_F170I,Pab1_170,Pab1,Pab1,P04147,0.253165,NO,170,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.269,-3.256,1.987,,0.331,E,B,0.87,-1.31,2.061,,79.72,OHH,-1.06367,0.175299,0.000540225,0.253165 beta-lactamase_2500_V78Q,beta-lactamase_2500_78,TEM-1,beta-lactamase_2500,P62593,0.25317,NO,78,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.459,-4.26,2.801,,,H,A,0.44,-0.47,31.376,31.376,63.64,HHH,-1.17833,0.361275,0.00492501,0.25317 kka2_1:1_R217E,kka2_1:1_217,Kka2,kka2_1:1,P00552,0.253208,NO,217,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.158,-3.44,2.282,,0.252,T,A,1.2,-0.59,0.381,,52.27,ABH,-1.127,0.520039,0.0047191,0.253208 kka2_1:1_G10N,kka2_1:1_10,Kka2,kka2_1:1,P00552,0.253238,NO,10,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.921,-2.575,0.654,,,,,,,1.862,,71.59,HOP,-2.10733,0.520039,0.00289233,0.253238 kka2_1:1_A166I,kka2_1:1_166,Kka2,kka2_1:1,P00552,0.253313,NO,166,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.407,-3.972,1.565,,0.534,.,B,0.46,1.03,1.147,,71.59,HHO,-2.421,0.520039,0.00799912,0.253313 kka2_1:2_E235P,kka2_1:2_235,Kka2,kka2_1:2,P00552,0.253357,NO,235,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.955,-2.919,0.964,,0.631,H,A,1.04,0.12,26.048,26.048,65.53,OAH,-2.07267,0.295029,0.0102806,0.253357 kka2_1:8_I115G,kka2_1:8_115,Kka2,kka2_1:8,P00552,0.253385,NO,115,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.606,-3.814,2.208,,0.105,H,A,1.52,-1.18,4.064,,65.53,PHH,-2.205,0.100394,0.00836567,0.253385 kka2_1:8_I115G,kka2_1:8_115,Kka2,kka2_1:8,P00552,0.253385,NO,115,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.606,-3.814,2.208,,0.105,H,A,1.52,-1.18,4.064,,65.53,PHH,-2.205,0.100394,0.00836567,0.253385 kka2_1:8_W24E,kka2_1:8_24,Kka2,kka2_1:8,P00552,0.253385,NO,24,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-1.779,-4.036,2.257,,0.477,E,B,1.51,-0.21,2.503,,56.06,AHH,-2.24467,0.100394,0.00631564,0.253385 kka2_1:8_W24E,kka2_1:8_24,Kka2,kka2_1:8,P00552,0.253385,NO,24,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-1.779,-4.036,2.257,,0.477,E,B,1.51,-0.21,2.503,,56.06,AHH,-2.24467,0.100394,0.00631564,0.253385 beta-lactamase_156_T69R,beta-lactamase_156_69,TEM-1,beta-lactamase_156,P62593,0.253408,NO,69,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-0.973,-3.768,2.795,,,G,A,0.22,-1.24,4.194,,93.01,PPH,-1.01833,0.111618,0.00127498,0.253408 kka2_1:2_G189F,kka2_1:2_189,Kka2,kka2_1:2,P00552,0.253419,NO,189,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.596,-4.32,3.724,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.295029,0.00253688,0.253419 beta-lactamase_625_E35L,beta-lactamase_625_35,TEM-1,beta-lactamase_625,P62593,0.253428,NO,35,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-0.869,-3.632,2.763,,0.15,H,A,1.04,0.21,0.664,,46.85,HAA,-1.88667,0.213352,0.00174441,0.253428 kka2_1:1_L212N,kka2_1:1_212,Kka2,kka2_1:1,P00552,0.253445,NO,212,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.904,-4.173,3.269,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.520039,0.0031426,0.253445 kka2_1:1_V16P,kka2_1:1_16,Kka2,kka2_1:1,P00552,0.253488,NO,16,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-3.087,-4.081,0.994,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.520039,0.00694011,0.253488 kka2_1:1_Q219L,kka2_1:1_219,Kka2,kka2_1:1,P00552,0.253491,NO,219,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-0.93,-3.41,2.48,,0.088,H,A,0.4,-0.85,1.917,,50,HPA,-1.05167,0.520039,0.00237913,0.253491 beta-lactamase_2500_M115Y,beta-lactamase_2500_115,TEM-1,beta-lactamase_2500,P62593,0.253526,NO,115,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.389,-3.961,2.572,,0.019,E,B,0.55,0.08,3.261,,69.58,OHP,-1.25433,0.361275,0.0034337,0.253526 kka2_1:1_A255I,kka2_1:1_255,Kka2,kka2_1:1,P00552,0.25354,NO,255,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.715,-4.011,2.296,,0.466,H,A,0.46,-0.52,0.946,,65.53,HHH,-1.71267,0.520039,0.0126809,0.25354 beta-lactamase_G248D,beta-lactamase_248,TEM-1,beta-lactamase,P62593,0.253577,NO,248,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.794,-3.816,2.022,4.69798,,E,b,0.23,-0.43,1.782,,61.19,HOO,-1.52867,0.221079,0.00428493,0.253577 kka2_1:4_I115P,kka2_1:4_115,Kka2,kka2_1:4,P00552,0.253579,NO,115,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.606,-4.209,2.603,,0.105,H,A,1.52,-1.18,9.996,9.996,65.53,PHH,-2.205,0.168804,0.00836567,0.253579 kka2_1:4_D159N,kka2_1:4_159,Kka2,kka2_1:4,P00552,0.253601,NO,159,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.82,-3.315,2.495,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.168804,0.0030485,0.253601 beta-lactamase_156_I125D,beta-lactamase_156_125,TEM-1,beta-lactamase_156,P62593,0.253613,NO,125,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.441,-3.998,2.557,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.111618,0.00383964,0.253613 beta-lactamase_156_I277S,beta-lactamase_156_277,TEM-1,beta-lactamase_156,P62593,0.253643,NO,277,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.111618,0.0169305,0.253643 beta-lactamase_39_D129L,beta-lactamase_39_129,TEM-1,beta-lactamase_39,P62593,0.253665,NO,129,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.816,-3.806,2.99,,,,B,0.75,-0.69,0.56,,34.97,PAP,-0.818,0.0495842,0.00109178,0.253665 kka2_1:1_A215I,kka2_1:1_215,Kka2,kka2_1:1,P00552,0.253703,NO,215,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.968,-3.723,2.755,,0.039,E,B,0.46,-0.59,0.754,,50.38,HHA,-1.00467,0.520039,0.00529129,0.253703 kka2_1:8_H188V,kka2_1:8_188,Kka2,kka2_1:8,P00552,0.253704,NO,188,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-0.913,-3.78,2.867,,0.006,,A,0.87,-1.02,1.241,,47.73,PBO,-0.927333,0.100394,0.00273139,0.253704 kka2_1:8_H188V,kka2_1:8_188,Kka2,kka2_1:8,P00552,0.253704,NO,188,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-0.913,-3.78,2.867,,0.006,,A,0.87,-1.02,1.241,,47.73,PBO,-0.927333,0.100394,0.00273139,0.253704 beta-lactamase_625_T178L,beta-lactamase_625_178,TEM-1,beta-lactamase_625,P62593,0.253705,NO,178,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-0.791,-3.133,2.342,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.213352,0.000684366,0.253705 kka2_1:2_F203W,kka2_1:2_203,Kka2,kka2_1:2,P00552,0.25373,NO,203,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-0.911,-4.558,3.647,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.295029,0.00318738,0.25373 kka2_1:1_T187Y,kka2_1:1_187,Kka2,kka2_1:1,P00552,0.253732,NO,187,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.273,-4.308,3.035,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.520039,0.00693073,0.253732 kka2_1:1_T225Y,kka2_1:1_225,Kka2,kka2_1:1,P00552,0.253742,NO,225,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.393,-4.28,1.887,,0.036,H,A,0.22,-1.22,4.554,,63.64,HPB,-1.58733,0.520039,0.0113598,0.253742 beta-lactamase_2500_T179V,beta-lactamase_2500_179,TEM-1,beta-lactamase_2500,P62593,0.253753,NO,179,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.085,-3.247,2.162,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.361275,0.00226045,0.253753 beta-lactamase_156_A247P,beta-lactamase_156_247,TEM-1,beta-lactamase_156,P62593,0.253762,NO,247,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.111618,0.00611275,0.253762 kka2_1:4_A144W,kka2_1:4_144,Kka2,kka2_1:4,P00552,0.253774,NO,144,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.859,-5.395,4.536,,,H,A,0.46,0.21,6.844,,52.65,BHB,-1.72933,0.168804,0.00231095,0.253774 kka2_1:1_L60C,kka2_1:1_60,Kka2,kka2_1:1,P00552,0.253843,NO,60,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.997,-4.773,3.776,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.520039,0.00262176,0.253843 kka2_1:1_D227M,kka2_1:1_227,Kka2,kka2_1:1,P00552,0.253863,NO,227,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.758,-4.662,2.904,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.520039,0.00745029,0.253863 kka2_1:4_G210E,kka2_1:4_210,Kka2,kka2_1:4,P00552,0.253865,NO,210,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.095,-3.693,2.598,,0.103,T,A,0.29,-0.62,0.271,,50,OOB,-0.966667,0.168804,0.00598378,0.253865 PSD95pdz3_V362D,PSD95pdz3_362,PSD95pdz3,PSD95pdz3,P31016,0.253878,NO,362,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.465,-3.6,2.135,4.99436,,,,,19.6443,,,,PHP,-1.46467,0.0758425,0.000538527,0.253878 kka2_1:1_K175H,kka2_1:1_175,Kka2,kka2_1:1,P00552,0.25388,NO,175,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-2.897,-3.28,0.383,,0.579,H,A,1.3,0.51,9.33,9.33,71.59,HBH,-1.82333,0.520039,0.00693093,0.25388 beta-lactamase_M115W,beta-lactamase_115,TEM-1,beta-lactamase,P62593,0.253893,NO,115,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.389,-5.031,3.642,4.89743,0.019,E,B,1.3,0.08,1.236,,69.58,OHP,-1.25433,0.221079,0.0034337,0.253893 beta-lactamase_N272Y,beta-lactamase_272,TEM-1,beta-lactamase,P62593,0.253893,NO,272,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-1.127,-4.275,3.148,5.37826,0.081,H,A,0.09,-0.97,1.468,,63.64,BPB,-1.56333,0.221079,0.00545371,0.253893 kka2_1:2_D261K,kka2_1:2_261,Kka2,kka2_1:2,P00552,0.253963,NO,261,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.708,-3.485,2.777,,0.146,G,A,0.75,-0.33,,,,HAA,-0.759333,0.295029,0.0224846,0.253963 kka2_1:2_K112H,kka2_1:2_112,Kka2,kka2_1:2,P00552,0.253974,NO,112,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-2.491,-4.863,2.372,,0.076,H,A,2.34,-1.37,23.433,23.433,56.06,ABH,-2.00133,0.295029,0.00645389,0.253974 beta-lactamase_625_D129Y,beta-lactamase_625_129,TEM-1,beta-lactamase_625,P62593,0.254043,NO,129,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.816,-4.385,3.569,,,,B,0.75,-0.69,0.171,,34.97,PAP,-0.818,0.213352,0.00109178,0.254043 kka2_1:1_L67A,kka2_1:1_67,Kka2,kka2_1:1,P00552,0.254056,NO,67,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.741,-3.106,2.365,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.520039,0.00102787,0.254056 kka2_1:2_R211W,kka2_1:2_211,Kka2,kka2_1:2,P00552,0.254074,NO,211,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-0.899,-2.964,2.065,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.295029,0.00204888,0.254074 kka2_1:2_V186C,kka2_1:2_186,Kka2,kka2_1:2,P00552,0.254077,NO,186,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.011,-4.765,3.754,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.295029,0.00409703,0.254077 kka2_1:1_G30L,kka2_1:1_30,Kka2,kka2_1:1,P00552,0.254153,NO,30,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.596,-3.836,3.24,,0.54,S,g,0.29,3.76,,,,HOO,-1.51133,0.520039,0.00159208,0.254153 kka2_1:1_L174H,kka2_1:1_174,Kka2,kka2_1:1,P00552,0.254187,NO,174,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.952,-4.968,4.016,,,H,A,0.55,-0.31,13.276,13.276,51.89,BHB,-2.08533,0.520039,0.00438501,0.254187 PSD95pdz3_G329M,PSD95pdz3_329,PSD95pdz3,PSD95pdz3,P31016,0.254252,NO,329,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.008,-4.612,3.604,4.7671,,,,,19.7075,,,,HOO,-1.16033,0.0758425,0.000974577,0.254252 beta-lactamase_625_L191G,beta-lactamase_625_191,TEM-1,beta-lactamase_625,P62593,0.254254,NO,191,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.087,-3.655,2.568,,,H,A,0.55,0.09,1.908,,63.29,BHH,-1.445,0.213352,0.00263549,0.254254 beta-lactamase_625_L146D,beta-lactamase_625_146,TEM-1,beta-lactamase_625,P62593,0.254345,NO,146,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.462,-4.108,2.646,,0.007,H,A,0.55,-0.56,2.16,,64.69,AHP,-1.656,0.213352,0.00474542,0.254345 beta-lactamase_625_L79G,beta-lactamase_625_79,TEM-1,beta-lactamase_625,P62593,0.254439,NO,79,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.842,-3.806,2.964,,0.007,H,A,0.55,-0.16,0.935,,50.35,HHP,-1.44333,0.213352,0.000947397,0.254439 kka2_1:4_F264H,kka2_1:4_264,Kka2,kka2_1:4,P00552,0.254473,NO,264,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.02,-4.405,3.385,,0.296,,?,1.62,0.02,1.93,,71.59,HHO,-0.9655,0.168804,,0.254473 beta-lactamase_156_K232G,beta-lactamase_156_232,TEM-1,beta-lactamase_156,P62593,0.254529,NO,232,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.012,-3.401,2.389,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.111618,0.00313441,0.254529 kka2_1:1_H124G,kka2_1:1_124,Kka2,kka2_1:1,P00552,0.254529,NO,124,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-0.84,-3.386,2.546,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.520039,0.00211296,0.254529 kka2_1:1_C77D,kka2_1:1_77,Kka2,kka2_1:1,P00552,0.254539,NO,77,C,D,CD,Special,negativeCharge,5.07,5.0516,-0.0184,154,121,133,12,108.5,111.1,2.6,-1.477,-3.887,2.41,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.520039,0.00441216,0.254539 beta-lactamase_625_C121K,beta-lactamase_625_121,TEM-1,beta-lactamase_625,P62593,0.254567,NO,121,C,K,CK,Special,PositiveCharge,5.07,9.74,4.67,202,121,146,25,108.5,168.6,60.1,-0.953,-3.72,2.767,,,H,A,0.46,-0.81,1.143,,63.29,HOP,-1.46767,0.213352,0.000744322,0.254567 E1_Ubiquitin_R72P,E1_Ubiquitin_72,Uba1,E1_Ubiquitin,P0CG63,0.254642,NO,72,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.184,-3.697,2.513,,0.077,,B,0.16,-0.1,,,,HBH,-1.08733,0.18783,0.00129853,0.254642 beta-lactamase_2500_L47D,beta-lactamase_2500_47,TEM-1,beta-lactamase_2500,P62593,0.254648,NO,47,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.876,-3.931,2.055,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.361275,0.00439844,0.254648 beta-lactamase_2500_I280N,beta-lactamase_2500_280,TEM-1,beta-lactamase_2500,P62593,0.254683,NO,280,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.361275,0.0530888,0.254683 kka2_1:4_D101R,kka2_1:4_101,Kka2,kka2_1:4,P00552,0.254703,NO,101,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.028,-3.968,2.94,,0.213,E,B,0.75,-1.24,8.707,,63.64,PAH,-1.534,0.168804,0.00423361,0.254703 PSD95pdz3_A347W,PSD95pdz3_347,PSD95pdz3,PSD95pdz3,P31016,0.25475,NO,347,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.307,-5.004,3.697,4.89689,,,,,15.176,,,,OHA,-1.269,0.0758425,0.00074525,0.25475 kka2_1:1_G213F,kka2_1:1_213,Kka2,kka2_1:1,P00552,0.254771,NO,213,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.596,-4.32,3.724,,,E,b,0.29,-0.4,,,,HOH,-0.920333,0.520039,0.00187654,0.254771 kka2_1:2_V80Y,kka2_1:2_80,Kka2,kka2_1:2,P00552,0.2548,NO,80,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.144,-4.109,2.965,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.295029,0.00488211,0.2548 kka2_1:8_A224F,kka2_1:8_224,Kka2,kka2_1:8,P00552,0.254819,NO,224,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.977,-4.161,3.184,,,H,A,0.46,-1.26,0.357,,63.64,HHP,-1.41033,0.100394,0.00352047,0.254819 kka2_1:8_A224F,kka2_1:8_224,Kka2,kka2_1:8,P00552,0.254819,NO,224,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.977,-4.161,3.184,,,H,A,0.46,-1.26,0.357,,63.64,HHP,-1.41033,0.100394,0.00352047,0.254819 kka2_1:1_Y257G,kka2_1:1_257,Kka2,kka2_1:1,P00552,0.25502,NO,257,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-1.064,-3.67,2.606,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.520039,0.0148191,0.25502 kka2_1:1_E142M,kka2_1:1_142,Kka2,kka2_1:1,P00552,0.25505,NO,142,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.221,-4.819,2.598,,0.471,H,A,1.52,0.85,3.626,,65.53,HAB,-2.08033,0.520039,0.00748883,0.25505 kka2_1:4_F206K,kka2_1:4_206,Kka2,kka2_1:4,P00552,0.255069,NO,206,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.349,-3.906,2.557,,0.006,E,B,0.58,-1.21,1.342,,63.64,OHH,-1.04,0.168804,0.00936868,0.255069 kka2_1:1_R147Q,kka2_1:1_147,Kka2,kka2_1:1,P00552,0.255188,NO,147,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.123,-2.836,1.713,,0.094,H,A,1.2,0.97,2.578,,64.02,PBH,-1.98267,0.520039,0.00549168,0.255188 beta-lactamase_625_P65E,beta-lactamase_625_65,TEM-1,beta-lactamase_625,P62593,0.255216,NO,65,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.894,-3.524,2.63,,0.098,E,B,0.52,-0.62,0.3,,40.56,HOH,-1.03233,0.213352,0.00152776,0.255216 kka2_1:2_S105E,kka2_1:2_105,Kka2,kka2_1:2,P00552,0.255252,NO,105,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.945,-2.784,0.839,,0.056,S,B,0.27,-1.04,3.442,,65.53,PPB,-2.17033,0.295029,0.00847233,0.255252 kka2_1:4_F48K,kka2_1:4_48,Kka2,kka2_1:4,P00552,0.255275,NO,48,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.453,-3.972,2.519,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.168804,0.00475422,0.255275 kka2_1:8_I196N,kka2_1:8_196,Kka2,kka2_1:8,P00552,0.255296,NO,196,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-2.115,-4.284,2.169,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.100394,0.0107273,0.255296 kka2_1:8_I196N,kka2_1:8_196,Kka2,kka2_1:8,P00552,0.255296,NO,196,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-2.115,-4.284,2.169,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.100394,0.0107273,0.255296 kka2_1:8_I228D,kka2_1:8_228,Kka2,kka2_1:8,P00552,0.255296,NO,228,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.142,-4.061,2.919,,,H,A,1.52,-1.2,1.521,,71.59,AHH,-1.54633,0.100394,0.00458834,0.255296 kka2_1:8_I228D,kka2_1:8_228,Kka2,kka2_1:8,P00552,0.255296,NO,228,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.142,-4.061,2.919,,,H,A,1.52,-1.2,1.521,,71.59,AHH,-1.54633,0.100394,0.00458834,0.255296 beta-lactamase_156_D129S,beta-lactamase_156_129,TEM-1,beta-lactamase_156,P62593,0.255314,NO,129,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.816,-3.186,2.37,,,,B,0.75,-0.69,1.924,,34.97,PAP,-0.818,0.111618,0.00109178,0.255314 kka2_1:1_A64L,kka2_1:1_64,Kka2,kka2_1:1,P00552,0.255353,NO,64,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.496,-2.596,1.1,,0.039,H,A,0.46,-0.57,1.175,,56.06,AHH,-1.334,0.520039,0.00705578,0.255353 beta-lactamase_39_D129W,beta-lactamase_39_129,TEM-1,beta-lactamase_39,P62593,0.255387,NO,129,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.816,-5.545,4.729,,,,B,0.75,-0.69,0.56,,34.97,PAP,-0.818,0.0495842,0.00109178,0.255387 kka2_1:2_V97K,kka2_1:2_97,Kka2,kka2_1:2,P00552,0.255416,NO,97,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.453,-3.837,2.384,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.295029,0.00737869,0.255416 kka2_1:4_L212A,kka2_1:4_212,Kka2,kka2_1:4,P00552,0.255427,NO,212,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.904,-2.253,1.349,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.168804,0.0031426,0.255427 beta-lactamase_2500_G249W,beta-lactamase_2500_249,TEM-1,beta-lactamase_2500,P62593,0.25544,NO,249,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.312,,,,0.256,S,B,0.23,0.04,30.841,30.841,72.73,HOO,-1.81367,0.361275,0.00220169,0.25544 kka2_1:2_L39E,kka2_1:2_39,Kka2,kka2_1:2,P00552,0.255441,NO,39,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.223,-3.962,2.739,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.295029,0.00493618,0.255441 kka2_1:1_Y22I,kka2_1:1_22,Kka2,kka2_1:1,P00552,0.255447,NO,22,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-1.583,-3.083,1.5,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.520039,0.00598977,0.255447 kka2_1:1_Q42N,kka2_1:1_42,Kka2,kka2_1:1,P00552,0.25545,NO,42,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.907,-2.98,0.073,,1.044,T,B,0.4,-0.8,2.792,,71.59,HPO,-2.12433,0.520039,0.00679212,0.25545 kka2_1:8_Y257P,kka2_1:8_257,Kka2,kka2_1:8,P00552,0.255454,NO,257,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-1.064,-4.26,3.196,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.100394,0.0148191,0.255454 kka2_1:8_Y257P,kka2_1:8_257,Kka2,kka2_1:8,P00552,0.255454,NO,257,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-1.064,-4.26,3.196,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.100394,0.0148191,0.255454 beta-lactamase_2500_Y262P,beta-lactamase_2500_262,TEM-1,beta-lactamase_2500,P62593,0.255518,NO,262,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.361275,0.00853516,0.255518 beta-lactamase_2500_D48Y,beta-lactamase_2500_48,TEM-1,beta-lactamase_2500,P62593,0.255525,NO,48,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.101,-4.182,3.081,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.361275,0.0027273,0.255525 kka2_1:2_V214C,kka2_1:2_214,Kka2,kka2_1:2,P00552,0.25558,NO,214,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.261,-3.243,1.982,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.295029,0.00692782,0.25558 beta-lactamase_2500_D129M,beta-lactamase_2500_129,TEM-1,beta-lactamase_2500,P62593,0.255624,NO,129,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.816,-4.927,4.111,,,,B,0.75,-0.69,1.29,,34.97,PAP,-0.818,0.361275,0.00109178,0.255624 kka2_1:4_Y257A,kka2_1:4_257,Kka2,kka2_1:4,P00552,0.25563,NO,257,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-1.064,-3.39,2.326,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.168804,0.0148191,0.25563 beta-lactamase_156_L74Y,beta-lactamase_156_74,TEM-1,beta-lactamase_156,P62593,0.255632,NO,74,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.296,-4.105,2.809,,,H,A,0.55,-0.91,0.746,,50,HHO,-1.34933,0.111618,0.00493255,0.255632 beta-lactamase_625_L197D,beta-lactamase_625_197,TEM-1,beta-lactamase_625,P62593,0.255663,NO,197,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.853,-4.107,3.254,,0.007,S,B,0.55,0.33,1.756,,60.14,HHP,-1.833,0.213352,0.00144602,0.255663 kka2_1:1_D261P,kka2_1:1_261,Kka2,kka2_1:1,P00552,0.255665,NO,261,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.708,-3.683,2.975,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.520039,0.0224846,0.255665 beta-lactamase_2500_S233W,beta-lactamase_2500_233,TEM-1,beta-lactamase_2500,P62593,0.255714,NO,233,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.886,-5.339,3.453,,0.016,E,B,0.27,-1.01,2.851,,77.62,BPO,-1.17267,0.361275,0.00311415,0.255714 kka2_1:1_P128W,kka2_1:1_128,Kka2,kka2_1:1,P00552,0.255715,NO,128,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.922,-3.525,1.603,,0.316,G,A,0.52,0.4,2.178,,56.06,AOH,-1.64733,0.520039,0.00774689,0.255715 beta-lactamase_2500_A123K,beta-lactamase_2500_123,TEM-1,beta-lactamase_2500,P62593,0.255787,NO,123,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.834,-3.506,2.672,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.361275,0.0010157,0.255787 kka2_1:4_C31I,kka2_1:4_31,Kka2,kka2_1:4,P00552,0.255792,NO,31,C,I,CI,Special,Hydrophobic,5.07,6.02,0.95,198,121,131,10,108.5,166.7,58.2,-2.246,-3.907,1.661,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.168804,0.00681582,0.255792 beta-lactamase_2500_G142K,beta-lactamase_2500_142,TEM-1,beta-lactamase_2500,P62593,0.255796,NO,142,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.707,-3.645,2.938,,0.034,,p,0.29,-0.64,1.883,,64.69,OOO,-0.834,0.361275,0.00060149,0.255796 kka2_1:2_A237K,kka2_1:2_237,Kka2,kka2_1:2,P00552,0.255825,NO,237,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.12,-3.814,1.694,,0.068,H,A,0.46,-0.71,2.369,,92.05,HHA,-2.10433,0.295029,0.012257,0.255825 kka2_1:1_A144Y,kka2_1:1_144,Kka2,kka2_1:1,P00552,0.25585,NO,144,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.859,-4.19,3.331,,,H,A,0.46,0.21,0.842,,52.65,BHB,-1.72933,0.520039,0.00231095,0.25585 WW_domain_G176V,WW_domain_176,Yap65,WW_domain,P46937,0.255855,NO,176,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.235,-3.448,2.213,6.33142,,,,,,2.71,,78.57,HOH,-1.35467,0.153962,0.00288552,0.255855 kka2_1:1_I207W,kka2_1:1_207,Kka2,kka2_1:1,P00552,0.255869,NO,207,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.175,-5.409,4.234,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.520039,0.00611824,0.255869 kka2_1:1_A108L,kka2_1:1_108,Kka2,kka2_1:1,P00552,0.255924,NO,108,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.061,-2.851,0.79,,0.243,.,B,0.46,-1.34,3.156,,71.59,HHO,-1.57033,0.520039,0.00751209,0.255924 kka2_1:1_Y244I,kka2_1:1_244,Kka2,kka2_1:1,P00552,0.255927,NO,244,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-0.775,-3.589,2.814,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.520039,0.00453187,0.255927 hsp90_W585N,hsp90_585,hsp90,hsp90,P02829,0.255954,NO,585,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-4.251,-3.051,0,5.31455,0.508,,B,1.22,0.43,,,,OHP,-3.17533,0.368192,0.000222939,0.255954 kka2_1:4_V84P,kka2_1:4_84,Kka2,kka2_1:4,P00552,0.255957,NO,84,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-2.279,-4.01,1.731,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.168804,0.00724019,0.255957 kka2_1:4_S204D,kka2_1:4_204,Kka2,kka2_1:4,P00552,0.255977,NO,204,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.353,-3.549,2.196,,0.144,E,A,0.27,-1.2,2.442,,65.53,HPO,-0.953333,0.168804,0.00881794,0.255977 beta-lactamase_156_C121W,beta-lactamase_156_121,TEM-1,beta-lactamase_156,P62593,0.256106,NO,121,C,W,CW,Special,Hydrophobic,5.07,5.89,0.82,215,121,204,83,108.5,227.8,119.3,-0.953,-5.146,4.193,,,H,A,0.46,-0.81,1.136,,63.29,HOP,-1.46767,0.111618,0.000744322,0.256106 kka2_1:1_A237D,kka2_1:1_237,Kka2,kka2_1:1,P00552,0.256113,NO,237,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.12,-2.999,0.879,,0.068,H,A,0.46,-0.71,2.369,,92.05,HHA,-2.10433,0.520039,0.012257,0.256113 beta-lactamase_2500_V72Q,beta-lactamase_2500_72,TEM-1,beta-lactamase_2500,P62593,0.256114,NO,72,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.658,-4.185,2.527,,,H,A,0.44,-1.03,2.079,,65.73,BHH,-1.32167,0.361275,0.00501194,0.256114 hsp90_S586Q,hsp90_586,hsp90,hsp90,P02829,0.256277,NO,586,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.764,-3.278,0,4.65438,,,B,0.93,0.15,,,,HPH,-3.157,0.368192,0.000222939,0.256277 kka2_1:1_H135K,kka2_1:1_135,Kka2,kka2_1:1,P00552,0.256351,NO,135,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-1.331,-3.419,2.088,,0.071,.,a,0.17,0.65,3.574,,53.03,ABP,-1.77367,0.520039,0.00532566,0.256351 kka2_1:2_H162F,kka2_1:2_162,Kka2,kka2_1:2,P00552,0.256358,NO,162,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-2.319,-4.187,1.868,,0.071,G,A,0.17,1.01,3.187,,64.39,ABP,-2.02067,0.295029,0.00616145,0.256358 kka2_1:8_D220M,kka2_1:8_220,Kka2,kka2_1:8,P00552,0.25636,NO,220,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.787,-4.844,4.057,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.100394,0.00158066,0.25636 kka2_1:8_D220M,kka2_1:8_220,Kka2,kka2_1:8,P00552,0.25636,NO,220,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.787,-4.844,4.057,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.100394,0.00158066,0.25636 beta-lactamase_625_T178M,beta-lactamase_625_178,TEM-1,beta-lactamase_625,P62593,0.256378,NO,178,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-0.791,-4.48,3.689,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.213352,0.000684366,0.256378 kka2_1:8_E59R,kka2_1:8_59,Kka2,kka2_1:8,P00552,0.256405,NO,59,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-0.952,-3.602,2.65,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.100394,0.00280355,0.256405 kka2_1:8_E59R,kka2_1:8_59,Kka2,kka2_1:8,P00552,0.256405,NO,59,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-0.952,-3.602,2.65,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.100394,0.00280355,0.256405 beta-lactamase_2500_F70E,beta-lactamase_2500_70,TEM-1,beta-lactamase_2500,P62593,0.256452,NO,70,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.169,-3.82,2.651,,,H,A,0.58,-1.34,1.918,,63.99,PHB,-0.980667,0.361275,0.00193499,0.256452 kka2_1:1_L170H,kka2_1:1_170,Kka2,kka2_1:1,P00552,0.256465,NO,170,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.28,-5.007,3.727,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.520039,0.00730791,0.256465 kka2_1:2_I228N,kka2_1:2_228,Kka2,kka2_1:2,P00552,0.256495,NO,228,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.142,-4.223,3.081,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.295029,0.00458834,0.256495 beta-lactamase_2500_R63G,beta-lactamase_2500_63,TEM-1,beta-lactamase_2500,P62593,0.256507,NO,63,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-0.943,-3.426,2.483,,0.218,,B,1.2,-0.31,0.929,,44.06,ABH,-0.992333,0.361275,0.00126938,0.256507 beta-lactamase_2500_W208G,beta-lactamase_2500_208,TEM-1,beta-lactamase_2500,P62593,0.256519,NO,208,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-0.818,-3.358,2.54,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.361275,0.00126609,0.256519 kka2_1:4_C131Y,kka2_1:4_131,Kka2,kka2_1:4,P00552,0.256519,NO,131,C,Y,CY,Special,Hydrophobic,5.07,5.66,0.59,194,121,181,60,108.5,193.6,85.1,-0.831,-4.191,3.36,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.168804,0.00170814,0.256519 beta-lactamase_625_A230Q,beta-lactamase_625_230,TEM-1,beta-lactamase_625,P62593,0.256538,NO,230,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.154,-4.025,2.871,,0.01,E,B,0.46,-1.17,0.777,,50,HHA,-1.079,0.213352,0.00516841,0.256538 kka2_1:8_G99W,kka2_1:8_99,Kka2,kka2_1:8,P00552,0.256563,NO,99,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.596,-5.126,4.53,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.100394,0.00186055,0.256563 kka2_1:8_G99W,kka2_1:8_99,Kka2,kka2_1:8,P00552,0.256563,NO,99,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.596,-5.126,4.53,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.100394,0.00186055,0.256563 kka2_1:4_G95I,kka2_1:4_95,Kka2,kka2_1:4,P00552,0.256618,NO,95,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-2.403,-3.966,1.563,,0.126,E,B,0.29,-0.74,0.359,,71.59,HOA,-2.198,0.168804,0.00743616,0.256618 kka2_1:4_C192H,kka2_1:4_192,Kka2,kka2_1:4,P00552,0.256695,NO,192,C,H,CH,Special,PositiveCharge,5.07,7.59,2.52,174,121,155,34,108.5,153.2,44.7,-1.067,-4.779,3.712,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.168804,0.00485428,0.256695 kka2_1:8_L174K,kka2_1:8_174,Kka2,kka2_1:8,P00552,0.256721,NO,174,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.952,-3.744,2.792,,,H,A,1.59,-0.31,1.204,,51.89,BHB,-2.08533,0.100394,0.00438501,0.256721 kka2_1:8_L174K,kka2_1:8_174,Kka2,kka2_1:8,P00552,0.256721,NO,174,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.952,-3.744,2.792,,,H,A,1.59,-0.31,1.204,,51.89,BHB,-2.08533,0.100394,0.00438501,0.256721 kka2_1:2_P179N,kka2_1:2_179,Kka2,kka2_1:2,P00552,0.256783,NO,179,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.974,-3.967,2.993,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.295029,0.00298346,0.256783 kka2_1:1_I254P,kka2_1:1_254,Kka2,kka2_1:1,P00552,0.256802,NO,254,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.933,-4.189,2.256,,0.135,H,A,1.52,-0.6,1.859,,71.59,BHH,-1.668,0.520039,0.0132375,0.256802 kka2_1:2_V49Q,kka2_1:2_49,Kka2,kka2_1:2,P00552,0.256842,NO,49,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.614,-4.261,2.647,,,E,B,0.44,-0.77,1.233,,64.39,HHB,-1.3,0.295029,0.00615685,0.256842 kka2_1:8_N200P,kka2_1:8_200,Kka2,kka2_1:8,P00552,0.256872,NO,200,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-2.446,-4.046,1.6,,0.756,T,L,0.43,-0.08,2.528,,64.39,APO,-2.08,0.100394,0.00838549,0.256872 kka2_1:8_N200P,kka2_1:8_200,Kka2,kka2_1:8,P00552,0.256872,NO,200,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-2.446,-4.046,1.6,,0.756,T,L,0.43,-0.08,2.528,,64.39,APO,-2.08,0.100394,0.00838549,0.256872 beta-lactamase_625_E119P,beta-lactamase_625_119,TEM-1,beta-lactamase_625,P62593,0.256948,NO,119,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.412,-3.828,2.416,,0.358,H,A,1.04,0.51,1.034,,63.99,BAH,-1.623,0.213352,0.00386966,0.256948 beta-lactamase_39_E46P,beta-lactamase_39_46,TEM-1,beta-lactamase_39,P62593,0.256975,NO,46,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.94,-4.039,2.099,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.0495842,0.00427568,0.256975 kka2_1:2_L193G,kka2_1:2_193,Kka2,kka2_1:2,P00552,0.257028,NO,193,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.983,-3.8,2.817,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.295029,0.00480179,0.257028 kka2_1:2_G210D,kka2_1:2_210,Kka2,kka2_1:2,P00552,0.257051,NO,210,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.095,-3.632,2.537,,0.103,T,A,0.29,-0.62,0.271,,50,OOB,-0.966667,0.295029,0.00598378,0.257051 kka2_1:4_L232S,kka2_1:4_232,Kka2,kka2_1:4,P00552,0.257084,NO,232,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.514,-3.04,1.526,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.168804,0.00800103,0.257084 kka2_1:4_A119L,kka2_1:4_119,Kka2,kka2_1:4,P00552,0.257123,NO,119,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.073,-3.266,2.193,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.168804,0.00441074,0.257123 kka2_1:4_A191D,kka2_1:4_191,Kka2,kka2_1:4,P00552,0.257208,NO,191,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.831,-3.72,2.889,,,.,b,0.46,-0.94,2.046,,50,AHO,-0.868667,0.168804,0.00338807,0.257208 kka2_1:4_A237R,kka2_1:4_237,Kka2,kka2_1:4,P00552,0.257211,NO,237,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.12,-4.175,2.055,,0.068,H,A,0.46,-0.71,2.444,,92.05,HHA,-2.10433,0.168804,0.012257,0.257211 kka2_1:1_A25N,kka2_1:1_25,Kka2,kka2_1:1,P00552,0.257248,NO,25,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.496,-3.071,0.575,,0.427,E,B,0.46,-0.47,6.872,6.872,65.53,HHP,-2.15167,0.520039,0.00595636,0.257248 beta-lactamase_2500_Y262A,beta-lactamase_2500_262,TEM-1,beta-lactamase_2500,P62593,0.257273,NO,262,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.361275,0.00853516,0.257273 Pab1_G150I,Pab1_150,Pab1,Pab1,P04147,0.257281,NO,150,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.809,-4.052,3.243,,0.287,S,b,0.23,0.53,,,,HOA,-1.45233,0.175299,0.000323835,0.257281 kka2_1:2_L170I,kka2_1:2_170,Kka2,kka2_1:2,P00552,0.257322,NO,170,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.28,-2.562,1.282,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.295029,0.00730791,0.257322 kka2_1:8_I207P,kka2_1:8_207,Kka2,kka2_1:8,P00552,0.257353,NO,207,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.175,-4.149,2.974,,0.293,,B,1.52,-1.12,1.306,,56.06,HHA,-1.07733,0.100394,0.00611824,0.257353 kka2_1:8_I207P,kka2_1:8_207,Kka2,kka2_1:8,P00552,0.257353,NO,207,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.175,-4.149,2.974,,0.293,,B,1.52,-1.12,1.306,,56.06,HHA,-1.07733,0.100394,0.00611824,0.257353 beta-lactamase_625_M66N,beta-lactamase_625_66,TEM-1,beta-lactamase_625,P62593,0.257355,NO,66,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.362,-4.083,2.721,,0.013,,A,0.55,-0.7,1.659,,73.08,OHH,-1.49567,0.213352,0.00412876,0.257355 kka2_1:2_V46W,kka2_1:2_46,Kka2,kka2_1:2,P00552,0.257355,NO,46,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-2.62,-5.568,2.948,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.295029,0.00631301,0.257355 beta-lactamase_E119V,beta-lactamase_119,TEM-1,beta-lactamase,P62593,0.257496,NO,119,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.412,-3.661,2.249,5.33349,0.358,H,A,1.52,0.51,1.983,,63.99,BAH,-1.623,0.221079,0.00386966,0.257496 Pab1_G150R,Pab1_150,Pab1,Pab1,P04147,0.257515,NO,150,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.809,-3.75,2.941,,0.287,S,b,0.23,0.53,,,,HOA,-1.45233,0.175299,0.000323835,0.257515 kka2_1:1_A176G,kka2_1:1_176,Kka2,kka2_1:1,P00552,0.257516,NO,176,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.621,-3.323,1.702,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.520039,0.0083587,0.257516 beta-lactamase_L247Q,beta-lactamase_247,TEM-1,beta-lactamase,P62593,0.257522,NO,247,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.48,-4.243,2.763,5.28771,0.007,E,B,2.89,-0.72,2.951,,63.99,HHO,-1.79833,0.221079,0.00611275,0.257522 beta-lactamase_625_R91P,beta-lactamase_625_91,TEM-1,beta-lactamase_625,P62593,0.257525,NO,91,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.392,-3.876,2.484,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.213352,0.00380226,0.257525 beta-lactamase_2500_G114R,beta-lactamase_2500_114,TEM-1,beta-lactamase_2500,P62593,0.257554,NO,114,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.094,-2.891,1.797,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.361275,0.00224919,0.257554 beta-lactamase_2500_V157P,beta-lactamase_2500_157,TEM-1,beta-lactamase_2500,P62593,0.257604,NO,157,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.751,-4.03,2.279,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.361275,0.00506849,0.257604 kka2_1:2_L260Q,kka2_1:2_260,Kka2,kka2_1:2,P00552,0.257651,NO,260,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.741,-4.153,3.412,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.295029,0.0233782,0.257651 kka2_1:8_C131W,kka2_1:8_131,Kka2,kka2_1:8,P00552,0.257668,NO,131,C,W,CW,Special,Hydrophobic,5.07,5.89,0.82,215,121,204,83,108.5,227.8,119.3,-0.831,-5.126,4.295,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.100394,0.00170814,0.257668 kka2_1:8_C131W,kka2_1:8_131,Kka2,kka2_1:8,P00552,0.257668,NO,131,C,W,CW,Special,Hydrophobic,5.07,5.89,0.82,215,121,204,83,108.5,227.8,119.3,-0.831,-5.126,4.295,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.100394,0.00170814,0.257668 beta-lactamase_156_G236R,beta-lactamase_156_236,TEM-1,beta-lactamase_156,P62593,0.257707,NO,236,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.784,-3.932,3.148,,0.241,,b,0.29,-0.59,1.883,,64.69,HOO,-1.025,0.111618,0.00162372,0.257707 beta-lactamase_2500_L150H,beta-lactamase_2500_150,TEM-1,beta-lactamase_2500,P62593,0.257746,NO,150,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.326,-4.935,3.609,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.361275,0.00463171,0.257746 kka2_1:4_L39E,kka2_1:4_39,Kka2,kka2_1:4,P00552,0.257764,NO,39,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.223,-3.962,2.739,,,E,B,0.55,-1.21,1.998,,71.59,BHP,-1.69167,0.168804,0.00493618,0.257764 kka2_1:2_C77D,kka2_1:2_77,Kka2,kka2_1:2,P00552,0.257803,NO,77,C,D,CD,Special,negativeCharge,5.07,5.0516,-0.0184,154,121,133,12,108.5,111.1,2.6,-1.477,-3.887,2.41,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.295029,0.00441216,0.257803 kka2_1:8_D261W,kka2_1:8_261,Kka2,kka2_1:8,P00552,0.257826,NO,261,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.708,-5.576,4.868,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.100394,0.0224846,0.257826 kka2_1:8_D261W,kka2_1:8_261,Kka2,kka2_1:8,P00552,0.257826,NO,261,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.708,-5.576,4.868,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.100394,0.0224846,0.257826 beta-lactamase_625_G236R,beta-lactamase_625_236,TEM-1,beta-lactamase_625,P62593,0.257827,NO,236,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.784,-3.932,3.148,,0.241,,b,0.29,-0.59,3.506,,64.69,HOO,-1.025,0.213352,0.00162372,0.257827 beta-lactamase_2500_I258G,beta-lactamase_2500_258,TEM-1,beta-lactamase_2500,P62593,0.257884,NO,258,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.361275,0.007931,0.257884 kka2_1:2_F264E,kka2_1:2_264,Kka2,kka2_1:2,P00552,0.257888,NO,264,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.02,-3.943,2.923,,0.296,.,?,0.58,0.02,2.303,,71.59,HHNA,-0.9655,0.295029,,0.257888 beta-lactamase_2500_L47R,beta-lactamase_2500_47,TEM-1,beta-lactamase_2500,P62593,0.257961,NO,47,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.876,-2.668,0.792,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.361275,0.00439844,0.257961 kka2_1:1_F48H,kka2_1:1_48,Kka2,kka2_1:1,P00552,0.257986,NO,48,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.453,-4.549,3.096,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.520039,0.00475422,0.257986 kka2_1:1_T225L,kka2_1:1_225,Kka2,kka2_1:1,P00552,0.258001,NO,225,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.393,-2.612,0.219,,0.036,H,A,0.22,-1.22,4.554,,63.64,HPB,-1.58733,0.520039,0.0113598,0.258001 kka2_1:2_H188T,kka2_1:2_188,Kka2,kka2_1:2,P00552,0.258027,NO,188,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-0.913,-3.673,2.76,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.295029,0.00273139,0.258027 kka2_1:4_D261N,kka2_1:4_261,Kka2,kka2_1:4,P00552,0.258057,NO,261,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.708,-3.251,2.543,,0.146,G,A,0.75,-0.33,,,,HAA,-0.759333,0.168804,0.0224846,0.258057 Ubiquitin_G76T,Ubiquitin_76,Uba1,Ubiquitin,P0CG48,0.258065,NO,76,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.651,-2.877,1.226,5.7647,0.23,,B,0.12,0.08,9.665,9.665,34.31,OOO,-1.632,0.205827,0.000653872,0.258065 Ubiquitin_I44S,Ubiquitin_44,Uba1,Ubiquitin,P0CG48,0.258065,NO,44,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.566,-2.715,1.149,4.71256,,E,B,0.27,-1.17,5.26,,39.71,HHH,-1.38567,0.205827,0.000613305,0.258065 Ubiquitin_L15D,Ubiquitin_15,Uba1,Ubiquitin,P0CG48,0.258065,NO,15,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.082,-4.087,3.005,5.14718,0.029,E,B,1.16,-0.53,0.936,,38.69,PHA,-1.40833,0.205827,0.000519738,0.258065 Ubiquitin_L69R,Ubiquitin_69,Uba1,Ubiquitin,P0CG48,0.258065,NO,69,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.445,-2.972,1.527,4.75624,0.051,E,B,2.89,-0.94,7.106,,34.31,BHH,-1.72933,0.205827,0.000919136,0.258065 Ubiquitin_L8T,Ubiquitin_8,Uba1,Ubiquitin,P0CG48,0.258065,NO,8,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.723,-2.784,1.061,5.28016,0.664,T,A,0.08,-0.34,0.664,,29.05,PHP,-1.51567,0.205827,0.000726165,0.258065 Ubiquitin_Q49L,Ubiquitin_49,Uba1,Ubiquitin,P0CG48,0.258065,NO,49,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-1.941,-2.517,0.576,5.05026,0.403,E,B,,-0.59,,,,BPH,-1.49467,0.205827,0.000613067,0.258065 Ubiquitin_R42E,Ubiquitin_42,Uba1,Ubiquitin,P0CG48,0.258065,NO,42,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.571,-3.36,1.789,5.07805,0.244,E,B,0.68,-0.54,1.976,,72.85,PBH,-1.38967,0.205827,0.000622265,0.258065 Ubiquitin_R72V,Ubiquitin_72,Uba1,Ubiquitin,P0CG48,0.258065,NO,72,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.034,-2.692,0.658,5.19484,0.077,,B,1.41,-0.1,9.638,9.638,42.77,HBH,-1.82733,0.205827,0.000768249,0.258065 Ubiquitin_R74E,Ubiquitin_74,Uba1,Ubiquitin,P0CG48,0.258065,NO,74,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.739,-3.384,1.645,5.6462,0.838,T,A,0.98,3.15,9.119,9.119,34.31,HBO,-1.71767,0.205827,0.000894236,0.258065 kka2_1:1_E169A,kka2_1:1_169,Kka2,kka2_1:1,P00552,0.258069,NO,169,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.996,-2.303,0.307,,0.422,H,A,1.04,0.3,7.546,7.546,65.53,HAH,-1.755,0.520039,0.00730086,0.258069 kka2_1:8_D220L,kka2_1:8_220,Kka2,kka2_1:8,P00552,0.258141,NO,220,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.787,-3.669,2.882,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.100394,0.00158066,0.258141 kka2_1:8_D220L,kka2_1:8_220,Kka2,kka2_1:8,P00552,0.258141,NO,220,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.787,-3.669,2.882,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.100394,0.00158066,0.258141 kka2_1:4_E262V,kka2_1:4_262,Kka2,kka2_1:4,P00552,0.258183,NO,262,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-0.829,-3.58,2.751,,0.059,G,A,1.04,-0.18,2.383,,42.42,AAH,-0.816,0.168804,0.0191586,0.258183 beta-lactamase_2500_P143M,beta-lactamase_2500_143,TEM-1,beta-lactamase_2500,P62593,0.258188,NO,143,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.967,-4.554,3.587,,0.075,H,A,0.52,-0.37,0.479,,66.78,OOB,-1.354,0.361275,0.00114551,0.258188 kka2_1:1_H162M,kka2_1:1_162,Kka2,kka2_1:1,P00552,0.258214,NO,162,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-2.319,-4.675,2.356,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.520039,0.00616145,0.258214 beta-lactamase_2500_L49E,beta-lactamase_2500_49,TEM-1,beta-lactamase_2500,P62593,0.258249,NO,49,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.897,-3.608,1.711,,0.131,T,A,0.55,0.04,6.681,,64.69,AHP,-1.99233,0.361275,0.00401477,0.258249 kka2_1:1_S204M,kka2_1:1_204,Kka2,kka2_1:1,P00552,0.258249,NO,204,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.353,-4.656,3.303,,0.144,E,A,0.27,-1.2,3.022,,65.53,HPO,-0.953333,0.520039,0.00881794,0.258249 beta-lactamase_2500_R63D,beta-lactamase_2500_63,TEM-1,beta-lactamase_2500,P62593,0.258335,NO,63,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-0.943,-3.762,2.819,,0.218,,B,1.2,-0.31,0.929,,44.06,ABH,-0.992333,0.361275,0.00126938,0.258335 kka2_1:1_E235V,kka2_1:1_235,Kka2,kka2_1:1,P00552,0.258374,NO,235,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.955,-2.86,0.905,,0.631,H,A,1.52,0.12,8.521,,65.53,OAH,-2.07267,0.520039,0.0102806,0.258374 beta-lactamase_2500_I229Y,beta-lactamase_2500_229,TEM-1,beta-lactamase_2500,P62593,0.258436,NO,229,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.267,-4.04,2.773,,0.083,E,B,0.48,-0.76,3.875,,50,HHH,-1.58767,0.361275,0.00477249,0.258436 kka2_1:8_F263P,kka2_1:8_263,Kka2,kka2_1:8,P00552,0.258455,NO,263,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-0.911,-4.356,3.445,,0.006,G,A,1.62,-0.12,0.928,,45.83,AHH,-0.92,0.100394,0.0172454,0.258455 kka2_1:8_F263P,kka2_1:8_263,Kka2,kka2_1:8,P00552,0.258455,NO,263,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-0.911,-4.356,3.445,,0.006,G,A,1.62,-0.12,0.928,,45.83,AHH,-0.92,0.100394,0.0172454,0.258455 kka2_1:8_H124G,kka2_1:8_124,Kka2,kka2_1:8,P00552,0.258455,NO,124,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-0.84,-3.386,2.546,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.100394,0.00211296,0.258455 kka2_1:8_H124G,kka2_1:8_124,Kka2,kka2_1:8,P00552,0.258455,NO,124,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-0.84,-3.386,2.546,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.100394,0.00211296,0.258455 beta-lactamase_2500_T179H,beta-lactamase_2500_179,TEM-1,beta-lactamase_2500,P62593,0.25846,NO,179,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.085,-2.971,1.886,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.361275,0.00226045,0.25846 beta-lactamase_2500_P224V,beta-lactamase_2500_224,TEM-1,beta-lactamase_2500,P62593,0.258493,NO,224,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.893,-3.599,2.706,,0.383,,B,0.52,-0.3,2.666,,74.48,HOH,-1.26433,0.361275,0.00189564,0.258493 beta-lactamase_2500_R220F,beta-lactamase_2500_220,TEM-1,beta-lactamase_2500,P62593,0.25852,NO,220,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-0.942,-4.29,3.348,,0.295,I,A,1.2,-0.76,2.175,,74.48,HBP,-1.33633,0.361275,0.00232421,0.25852 kka2_1:4_L92E,kka2_1:4_92,Kka2,kka2_1:4,P00552,0.258533,NO,92,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.893,-3.919,3.026,,0.007,E,B,0.55,-0.19,1.447,,63.26,HHH,-0.962,0.168804,0.00307177,0.258533 kka2_1:1_D127F,kka2_1:1_127,Kka2,kka2_1:1,P00552,0.258536,NO,127,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.364,-4.509,3.145,,0.573,.,B,0.75,0.45,3.414,,50.38,HAO,-1.51067,0.520039,0.00660501,0.258536 kka2_1:2_Y257A,kka2_1:2_257,Kka2,kka2_1:2,P00552,0.258571,NO,257,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-1.064,-3.39,2.326,,0.022,H,A,0.21,-0.88,0.833,,52.65,HHB,-1.39333,0.295029,0.0148191,0.258571 kka2_1:4_G233Y,kka2_1:4_233,Kka2,kka2_1:4,P00552,0.25861,NO,233,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.748,-4.46,3.712,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.168804,0.00232366,0.25861 kka2_1:8_D216R,kka2_1:8_216,Kka2,kka2_1:8,P00552,0.258613,NO,216,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.785,-3.929,3.144,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.100394,0.00229969,0.258613 kka2_1:8_D216R,kka2_1:8_216,Kka2,kka2_1:8,P00552,0.258613,NO,216,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.785,-3.929,3.144,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.100394,0.00229969,0.258613 kka2_1:1_L47E,kka2_1:1_47,Kka2,kka2_1:1,P00552,0.258641,NO,47,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.265,-3.747,2.482,,0.139,E,B,0.55,-0.86,14.593,14.593,63.26,HHH,-1.77933,0.520039,0.00509386,0.258641 kka2_1:2_D261L,kka2_1:2_261,Kka2,kka2_1:2,P00552,0.258651,NO,261,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.708,-3.836,3.128,,0.146,G,A,0.75,-0.33,,,,HAA,-0.759333,0.295029,0.0224846,0.258651 beta-lactamase_2500_D129E,beta-lactamase_2500_129,TEM-1,beta-lactamase_2500,P62593,0.258668,NO,129,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.816,-2.232,1.416,,,,B,0.75,-0.69,1.29,,34.97,PAP,-0.818,0.361275,0.00109178,0.258668 kka2_1:1_G43Y,kka2_1:1_43,Kka2,kka2_1:1,P00552,0.258674,NO,43,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.587,-3.332,1.745,,0.862,T,l,0.75,-0.67,2.247,,63.26,POB,-2.18533,0.520039,0.0071925,0.258674 kka2_1:1_G213L,kka2_1:1_213,Kka2,kka2_1:1,P00552,0.258821,NO,213,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.596,-3.836,3.24,,,E,b,0.29,-0.4,,,,HOH,-0.920333,0.520039,0.00187654,0.258821 beta-lactamase_2500_A215L,beta-lactamase_2500_215,TEM-1,beta-lactamase_2500,P62593,0.25885,NO,215,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.503,-3.475,1.972,,,,a,0.46,-0.93,3.516,,74.48,HHO,-1.42633,0.361275,0.00544007,0.25885 kka2_1:1_W24M,kka2_1:1_24,Kka2,kka2_1:1,P00552,0.258889,NO,24,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-1.779,-3.383,1.604,,0.477,E,B,0.47,-0.21,2.375,,56.06,AHH,-2.24467,0.520039,0.00631564,0.258889 kka2_1:2_L70I,kka2_1:2_70,Kka2,kka2_1:2,P00552,0.258896,NO,70,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.017,-2.539,1.522,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.295029,0.00411884,0.258896 beta-lactamase_625_L120R,beta-lactamase_625_120,TEM-1,beta-lactamase_625,P62593,0.258899,NO,120,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.044,-2.871,1.827,,,H,A,0.55,-1.13,7.813,,64.69,AHO,-1.13633,0.213352,0.00143563,0.258899 beta-lactamase_I229E,beta-lactamase_229,TEM-1,beta-lactamase,P62593,0.258924,NO,229,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.267,-3.864,2.597,5.0911,0.083,E,B,1,-0.76,1.114,,50,HHH,-1.58767,0.221079,0.00477249,0.258924 beta-lactamase_2500_D161R,beta-lactamase_2500_161,TEM-1,beta-lactamase_2500,P62593,0.258949,NO,161,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.891,-3.902,3.011,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.361275,0.000897697,0.258949 kka2_1:1_D52R,kka2_1:1_52,Kka2,kka2_1:1,P00552,0.258959,NO,52,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.271,-3.572,1.301,,0.22,E,B,0.75,0.8,2.64,,71.59,PAH,-2.38367,0.520039,0.00175694,0.258959 gb1_A252L,gb1_252,gb1,gb1,P06654,0.258977,NO,252,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.175,-2.869,1.694,,,,,,,,,,PHA,-1.55967,0.177985,0.00125598,0.258977 gb1_L231R,gb1_231,gb1,gb1,P06654,0.258977,NO,231,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.603,-3.744,2.141,,,,,,,0.219,,11.83,BHH,-1.82633,0.177985,0.00322797,0.258977 gb1_N261L,gb1_261,gb1,gb1,P06654,0.258977,NO,261,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-1.863,-3.23,1.367,,,,,,,1.191,,44.87,HPA,-2.16033,0.177985,0.0061875,0.258977 gb1_N261V,gb1_261,gb1,gb1,P06654,0.258977,NO,261,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-1.863,-3.302,1.439,,,,,,,1.191,,44.87,HPA,-2.16033,0.177985,0.0061875,0.258977 gb1_V265N,gb1_265,gb1,gb1,P06654,0.258977,NO,265,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.843,-3.635,1.792,,,,,,,0.402,,11.83,OHA,-1.64567,0.177985,0.00360613,0.258977 gb1_Y229D,gb1_229,gb1,gb1,P06654,0.258977,NO,229,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-1.282,-3.654,2.372,,,,,,,,,,PHB,-1.4915,0.177985,0.00366605,0.258977 kka2_1:1_Q26F,kka2_1:1_26,Kka2,kka2_1:1,P00552,0.258995,NO,26,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.18,-4.426,2.246,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.520039,0.00708962,0.258995 kka2_1:1_L152H,kka2_1:1_152,Kka2,kka2_1:1,P00552,0.259014,NO,152,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.521,-4.868,3.347,,0.547,.,A,0.55,1.36,1.589,,63.64,OHH,-1.162,0.520039,0.00674868,0.259014 kka2_1:8_F264I,kka2_1:8_264,Kka2,kka2_1:8,P00552,0.259084,NO,264,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.02,-3.433,2.413,,0.296,,?,1.62,0.02,1.553,,71.59,HHO,-0.9655,0.100394,,0.259084 kka2_1:8_F264I,kka2_1:8_264,Kka2,kka2_1:8,P00552,0.259084,NO,264,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.02,-3.433,2.413,,0.296,,?,1.62,0.02,1.553,,71.59,HHO,-0.9655,0.100394,,0.259084 kka2_1:8_G213M,kka2_1:8_213,Kka2,kka2_1:8,P00552,0.259084,NO,213,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.596,-4.958,4.362,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.100394,0.00187654,0.259084 kka2_1:8_G213M,kka2_1:8_213,Kka2,kka2_1:8,P00552,0.259084,NO,213,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.596,-4.958,4.362,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.100394,0.00187654,0.259084 kka2_1:8_G99Y,kka2_1:8_99,Kka2,kka2_1:8,P00552,0.259084,NO,99,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.596,-4.416,3.82,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.100394,0.00186055,0.259084 kka2_1:8_G99Y,kka2_1:8_99,Kka2,kka2_1:8,P00552,0.259084,NO,99,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.596,-4.416,3.82,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.100394,0.00186055,0.259084 kka2_1:8_R121P,kka2_1:8_121,Kka2,kka2_1:8,P00552,0.259084,NO,121,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.552,-4.003,2.451,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.100394,0.00523326,0.259084 kka2_1:8_R121P,kka2_1:8_121,Kka2,kka2_1:8,P00552,0.259084,NO,121,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.552,-4.003,2.451,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.100394,0.00523326,0.259084 kka2_1:2_F263N,kka2_1:2_263,Kka2,kka2_1:2,P00552,0.259114,NO,263,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-0.911,-4.185,3.274,,0.006,G,A,1.62,-0.12,5.275,,45.83,AHH,-0.92,0.295029,0.0172454,0.259114 beta-lactamase_2500_R202D,beta-lactamase_2500_202,TEM-1,beta-lactamase_2500,P62593,0.25912,NO,202,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.292,-3.594,2.302,,0.188,H,A,1.2,0.62,3.734,,77.62,PBP,-1.54767,0.361275,0.00321899,0.25912 kka2_1:1_D118R,kka2_1:1_118,Kka2,kka2_1:1,P00552,0.259154,NO,118,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.07,-3.951,1.881,,0.61,H,A,0.75,-0.05,13.434,13.434,64.39,HAH,-1.32367,0.520039,0.0067852,0.259154 beta-lactamase_625_P181K,beta-lactamase_625_181,TEM-1,beta-lactamase_625,P62593,0.259163,NO,181,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.813,-3.483,2.67,,,H,A,0.52,-1.14,1.797,,61.54,HOH,-1.795,0.213352,0.000703122,0.259163 beta-lactamase_625_Y95Q,beta-lactamase_625_95,TEM-1,beta-lactamase_625,P62593,0.259164,NO,95,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-1.715,-4.267,2.552,,0.122,,b,0.21,-0.37,3.355,,77.62,BHP,-2.16167,0.213352,0.00479449,0.259164 kka2_1:4_F203E,kka2_1:4_203,Kka2,kka2_1:4,P00552,0.259176,NO,203,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-0.911,-3.952,3.041,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.168804,0.00318738,0.259176 kka2_1:2_K175Y,kka2_1:2_175,Kka2,kka2_1:2,P00552,0.259203,NO,175,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-2.897,-3.379,0.482,,0.579,H,A,1.3,0.51,15.629,15.629,71.59,HBH,-1.82333,0.295029,0.00693093,0.259203 beta-lactamase_156_L150P,beta-lactamase_156_150,TEM-1,beta-lactamase_156,P62593,0.25921,NO,150,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.326,-4.037,2.711,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.111618,0.00463171,0.25921 beta-lactamase_625_T69G,beta-lactamase_625_69,TEM-1,beta-lactamase_625,P62593,0.259251,NO,69,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-0.973,-3.289,2.316,,,G,A,0.22,-1.24,2.716,,93.01,PPH,-1.01833,0.213352,0.00127498,0.259251 kka2_1:2_A119W,kka2_1:2_119,Kka2,kka2_1:2,P00552,0.259255,NO,119,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.073,-5.403,4.33,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.295029,0.00441074,0.259255 kka2_1:4_D216N,kka2_1:4_216,Kka2,kka2_1:4,P00552,0.259257,NO,216,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.785,-3.274,2.489,,0.018,E,B,0.75,-0.51,0.112,,19.32,HAB,-0.970333,0.168804,0.00229969,0.259257 beta-lactamase_625_N274P,beta-lactamase_625_274,TEM-1,beta-lactamase_625,P62593,0.259361,NO,274,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.213352,0.0110418,0.259361 Pab1_G169P,Pab1_169,Pab1,Pab1,P04147,0.259373,NO,169,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.809,-3.697,2.888,,,E,b,0.35,0.03,,,,HOH,-1.11567,0.175299,0.000302434,0.259373 beta-lactamase_2500_D48F,beta-lactamase_2500_48,TEM-1,beta-lactamase_2500,P62593,0.259395,NO,48,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.101,-4.285,3.184,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.361275,0.0027273,0.259395 kka2_1:2_L212F,kka2_1:2_212,Kka2,kka2_1:2,P00552,0.259434,NO,212,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.904,-3.768,2.864,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.295029,0.0031426,0.259434 kka2_1:2_I207S,kka2_1:2_207,Kka2,kka2_1:2,P00552,0.259471,NO,207,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.175,-3.726,2.551,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.295029,0.00611824,0.259471 kka2_1:1_D154S,kka2_1:1_154,Kka2,kka2_1:1,P00552,0.259484,NO,154,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.876,-3.211,2.335,,0.457,.,b,0.75,1.48,0.658,,52.65,HAP,-1.52467,0.520039,0.00292633,0.259484 kka2_1:1_G233S,kka2_1:1_233,Kka2,kka2_1:1,P00552,0.259555,NO,233,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.748,-3.234,2.486,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.520039,0.00232366,0.259555 beta-lactamase_39_L188P,beta-lactamase_39_188,TEM-1,beta-lactamase_39,P62593,0.259582,NO,188,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.166,-4.109,2.943,,,H,A,0.55,-0.3,2.982,,60.14,PHB,-1.47033,0.0495842,0.00295687,0.259582 beta-lactamase_625_I277H,beta-lactamase_625_277,TEM-1,beta-lactamase_625,P62593,0.259612,NO,277,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.213352,0.0169305,0.259612 kka2_1:1_A34D,kka2_1:1_34,Kka2,kka2_1:1,P00552,0.259612,NO,34,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.928,-3.625,2.697,,0.417,.,B,0.46,2.29,0.262,,52.27,AHH,-1.747,0.520039,0.00343484,0.259612 beta-lactamase_625_G243H,beta-lactamase_625_243,TEM-1,beta-lactamase_625,P62593,0.259731,NO,243,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.213352,0.00464034,0.259731 kka2_1:1_D33F,kka2_1:1_33,Kka2,kka2_1:1,P00552,0.259732,NO,33,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.186,-4.506,2.32,,0.561,S,A,0.75,3.35,2.568,,71.59,PAH,-1.306,0.520039,0.00633568,0.259732 beta-lactamase_2500_L223E,beta-lactamase_2500_223,TEM-1,beta-lactamase_2500,P62593,0.259753,NO,223,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.055,-3.868,2.813,,0.27,,B,0.55,0.09,1.334,,74.48,HHO,-1.35033,0.361275,0.00372793,0.259753 kka2_1:1_A191Q,kka2_1:1_191,Kka2,kka2_1:1,P00552,0.259773,NO,191,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.831,-3.962,3.131,,,.,b,0.46,-0.94,0.53,,50,AHO,-0.868667,0.520039,0.00338807,0.259773 beta-lactamase_2500_S128G,beta-lactamase_2500_128,TEM-1,beta-lactamase_2500,P62593,0.25984,NO,128,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-0.84,-2.908,2.068,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.361275,0.00071483,0.25984 beta-lactamase_625_G76Q,beta-lactamase_625_76,TEM-1,beta-lactamase_625,P62593,0.259855,NO,76,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.189,-4.074,2.885,,,H,A,0.29,-0.67,3.059,,67.83,OOH,-1.22267,0.213352,0.00476637,0.259855 kka2_1:8_V49F,kka2_1:8_49,Kka2,kka2_1:8,P00552,0.259867,NO,49,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.614,-3.894,2.28,,,E,B,1.48,-0.77,1.31,,64.39,HHB,-1.3,0.100394,0.00615685,0.259867 kka2_1:8_V49F,kka2_1:8_49,Kka2,kka2_1:8,P00552,0.259867,NO,49,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.614,-3.894,2.28,,,E,B,1.48,-0.77,1.31,,64.39,HHB,-1.3,0.100394,0.00615685,0.259867 kka2_1:4_G210Y,kka2_1:4_210,Kka2,kka2_1:4,P00552,0.259898,NO,210,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.095,-4.42,3.325,,0.103,T,A,0.29,-0.62,0.271,,50,OOB,-0.966667,0.168804,0.00598378,0.259898 kka2_1:1_A144N,kka2_1:1_144,Kka2,kka2_1:1,P00552,0.259929,NO,144,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.859,-4.009,3.15,,,H,A,0.46,0.21,0.842,,52.65,BHB,-1.72933,0.520039,0.00231095,0.259929 beta-lactamase_156_F70P,beta-lactamase_156_70,TEM-1,beta-lactamase_156,P62593,0.259937,NO,70,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.169,-4.211,3.042,,,H,A,0.58,-1.34,1.918,,63.99,PHB,-0.980667,0.111618,0.00193499,0.259937 kka2_1:1_Q100A,kka2_1:1_100,Kka2,kka2_1:1,P00552,0.259954,NO,100,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.77,-2.603,-0.167,,0.646,E,B,0.4,-0.79,15.116,15.116,71.59,OPA,-1.46467,0.520039,0.0066405,0.259954 beta-lactamase_156_L74P,beta-lactamase_156_74,TEM-1,beta-lactamase_156,P62593,0.259958,NO,74,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.296,-4.001,2.705,,,H,A,0.55,-0.91,0.746,,50,HHO,-1.34933,0.111618,0.00493255,0.259958 kka2_1:2_Q26N,kka2_1:2_26,Kka2,kka2_1:2,P00552,0.259962,NO,26,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.18,-3.808,1.628,,0.448,E,B,0.4,0.44,5.022,,92.05,HPP,-2.11167,0.295029,0.00708962,0.259962 beta-lactamase_39_I244R,beta-lactamase_39_244,TEM-1,beta-lactamase_39,P62593,0.259977,NO,244,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.555,-4.183,2.628,,,E,B,0.48,-0.84,1.325,,77.62,OHH,-1.385,0.0495842,0.00605379,0.259977 beta-lactamase_2500_R257T,beta-lactamase_2500_257,TEM-1,beta-lactamase_2500,P62593,0.260044,NO,257,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.361275,0.00756629,0.260044 PSD95pdz3_A375P,PSD95pdz3_375,PSD95pdz3,PSD95pdz3,P31016,0.260047,NO,375,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.307,-3.336,2.029,5.05512,,,,,13.888,,,,PHH,-1.43767,0.0758425,0.000356809,0.260047 kka2_1:1_D220L,kka2_1:1_220,Kka2,kka2_1:1,P00552,0.260054,NO,220,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.787,-3.669,2.882,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.520039,0.00158066,0.260054 kka2_1:4_Y244D,kka2_1:4_244,Kka2,kka2_1:4,P00552,0.260133,NO,244,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-0.775,-3.947,3.172,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.168804,0.00453187,0.260133 kka2_1:4_N195W,kka2_1:4_195,Kka2,kka2_1:4,P00552,0.260139,NO,195,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-0.836,-5.599,4.763,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.168804,0.00276134,0.260139 kka2_1:4_F263K,kka2_1:4_263,Kka2,kka2_1:4,P00552,0.260145,NO,263,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-0.911,-3.934,3.023,,0.006,G,A,0.58,-0.12,2.284,,45.83,AHH,-0.92,0.168804,0.0172454,0.260145 kka2_1:1_D183V,kka2_1:1_183,Kka2,kka2_1:1,P00552,0.26017,NO,183,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.204,-2.92,1.716,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.520039,0.00426304,0.26017 kka2_1:1_V113W,kka2_1:1_113,Kka2,kka2_1:1,P00552,0.260174,NO,113,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.233,-5.432,4.199,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.520039,0.00650191,0.260174 kka2_1:8_F256I,kka2_1:8_256,Kka2,kka2_1:8,P00552,0.26018,NO,256,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.49,-3.685,2.195,,,H,A,1.62,-0.78,1.713,,53.03,HHH,-1.423,0.100394,0.0132841,0.26018 kka2_1:8_F256I,kka2_1:8_256,Kka2,kka2_1:8,P00552,0.26018,NO,256,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.49,-3.685,2.195,,,H,A,1.62,-0.78,1.713,,53.03,HHH,-1.423,0.100394,0.0132841,0.26018 kka2_1:1_F37M,kka2_1:1_37,Kka2,kka2_1:1,P00552,0.260199,NO,37,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.427,-4.497,3.07,,0.219,E,B,0.58,-0.25,18.64,18.64,64.39,HHB,-1.17733,0.520039,0.00586193,0.260199 kka2_1:4_H162K,kka2_1:4_162,Kka2,kka2_1:4,P00552,0.260211,NO,162,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-2.319,-3.151,0.832,,0.071,G,A,0.17,1.01,3.187,,64.39,ABP,-2.02067,0.168804,0.00616145,0.260211 kka2_1:4_I207H,kka2_1:4_207,Kka2,kka2_1:4,P00552,0.260244,NO,207,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.175,-5.02,3.845,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.168804,0.00611824,0.260244 beta-lactamase_625_K232A,beta-lactamase_625_232,TEM-1,beta-lactamase_625,P62593,0.260252,NO,232,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.012,-3.12,2.108,,,E,B,2.34,-1.1,1.992,,65.03,ABP,-1.238,0.213352,0.00313441,0.260252 kka2_1:2_D183V,kka2_1:2_183,Kka2,kka2_1:2,P00552,0.260262,NO,183,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.204,-2.92,1.716,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.295029,0.00426304,0.260262 hsp90_A587D,hsp90_587,hsp90,hsp90,P02829,0.260373,NO,587,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.456,-2.847,0,4.91216,0.049,H,A,0.55,-0.02,,,,PHP,-2.757,0.368192,0.000222939,0.260373 beta-lactamase_2500_A40R,beta-lactamase_2500_40,TEM-1,beta-lactamase_2500,P62593,0.260403,NO,40,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.402,-3.924,2.522,,0.155,S,B,0.46,0.21,0.953,,73.78,OHB,-1.40267,0.361275,0.00490026,0.260403 beta-lactamase_625_L120D,beta-lactamase_625_120,TEM-1,beta-lactamase_625,P62593,0.260469,NO,120,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.044,-4.076,3.032,,,H,A,0.55,-1.13,7.813,,64.69,AHO,-1.13633,0.213352,0.00143563,0.260469 beta-lactamase_625_N274Y,beta-lactamase_625_274,TEM-1,beta-lactamase_625,P62593,0.260495,NO,274,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.213352,0.0110418,0.260495 kka2_1:1_R217P,kka2_1:1_217,Kka2,kka2_1:1,P00552,0.260555,NO,217,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.158,-2.617,1.459,,0.252,T,A,1.2,-0.59,0.381,,52.27,ABH,-1.127,0.520039,0.0047191,0.260555 kka2_1:1_I196A,kka2_1:1_196,Kka2,kka2_1:1,P00552,0.260566,NO,196,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-2.115,-3.338,1.223,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.520039,0.0107273,0.260566 beta-lactamase_156_P65D,beta-lactamase_156_65,TEM-1,beta-lactamase_156,P62593,0.260607,NO,65,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.894,-3.578,2.684,,0.098,E,B,0.52,-0.62,0.623,,40.56,HOH,-1.03233,0.111618,0.00152776,0.260607 kka2_1:4_L19S,kka2_1:4_19,Kka2,kka2_1:4,P00552,0.260619,NO,19,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.254,-3.764,2.51,,0.08,T,A,1.59,-0.26,2.645,,65.53,BHH,-2.221,0.168804,0.00620703,0.260619 kka2_1:1_G181N,kka2_1:1_181,Kka2,kka2_1:1,P00552,0.260621,NO,181,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-2.698,-3.022,0.324,,0.379,S,B,0.75,0.78,15.356,15.356,71.59,AOA,-2.21,0.520039,0.00728319,0.260621 kka2_1:1_D190M,kka2_1:1_190,Kka2,kka2_1:1,P00552,0.260731,NO,190,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.708,-4.958,4.25,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.520039,0.00247989,0.260731 beta-lactamase_A123K,beta-lactamase_123,TEM-1,beta-lactamase,P62593,0.260734,NO,123,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.834,-3.506,2.672,4.70061,0.039,H,A,0.52,-0.72,0.705,,41.26,PHH,-1.47367,0.221079,0.0010157,0.260734 beta-lactamase_W286G,beta-lactamase_286,TEM-1,beta-lactamase,P62593,0.260734,NO,286,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-1.111,-3.175,2.064,6.64456,0.492,,?,0.01,0.6,,,,BHX,-1.478,0.221079,,0.260734 beta-lactamase_625_K232H,beta-lactamase_625_232,TEM-1,beta-lactamase_625,P62593,0.260753,NO,232,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.012,-4.433,3.421,,,E,B,2.34,-1.1,1.992,,65.03,ABP,-1.238,0.213352,0.00313441,0.260753 kka2_1:1_A144R,kka2_1:1_144,Kka2,kka2_1:1,P00552,0.260753,NO,144,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.859,-3.85,2.991,,,H,A,0.46,0.21,0.842,,52.65,BHB,-1.72933,0.520039,0.00231095,0.260753 beta-lactamase_2500_G114E,beta-lactamase_2500_114,TEM-1,beta-lactamase_2500,P62593,0.260798,NO,114,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.094,-3.605,2.511,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.361275,0.00224919,0.260798 kka2_1:8_L212D,kka2_1:8_212,Kka2,kka2_1:8,P00552,0.260805,NO,212,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.904,-4.134,3.23,,,,B,1.59,-0.78,1.708,,42.42,BHO,-0.799667,0.100394,0.0031426,0.260805 kka2_1:8_L212D,kka2_1:8_212,Kka2,kka2_1:8,P00552,0.260805,NO,212,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.904,-4.134,3.23,,,,B,1.59,-0.78,1.708,,42.42,BHO,-0.799667,0.100394,0.0031426,0.260805 kka2_1:4_D227L,kka2_1:4_227,Kka2,kka2_1:4,P00552,0.260827,NO,227,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.758,-3.54,1.782,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.168804,0.00745029,0.260827 kka2_1:1_V113M,kka2_1:1_113,Kka2,kka2_1:1,P00552,0.260842,NO,113,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.233,-3.136,1.903,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.520039,0.00650191,0.260842 kka2_1:1_R147W,kka2_1:1_147,Kka2,kka2_1:1,P00552,0.260847,NO,147,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.123,-5.411,4.288,,0.094,H,A,1.2,0.97,2.578,,64.02,PBH,-1.98267,0.520039,0.00549168,0.260847 kka2_1:2_G201P,kka2_1:2_201,Kka2,kka2_1:2,P00552,0.260886,NO,201,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.56,-3.175,1.615,,0.149,T,l,0.29,-0.57,16.092,16.092,52.65,POB,-1.92233,0.295029,0.00820117,0.260886 kka2_1:1_I207D,kka2_1:1_207,Kka2,kka2_1:1,P00552,0.260892,NO,207,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.175,-4.057,2.882,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.520039,0.00611824,0.260892 kka2_1:2_F171T,kka2_1:2_171,Kka2,kka2_1:2,P00552,0.260919,NO,171,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.326,-3.738,2.412,,0.154,H,A,0.58,-0.1,2.645,,63.64,HHH,-1.45433,0.295029,0.00821426,0.260919 kka2_1:2_A137P,kka2_1:2_137,Kka2,kka2_1:2,P00552,0.260939,NO,137,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.156,-4.148,1.992,,0.029,H,A,0.46,0.34,1.323,,63.26,PHB,-2.559,0.295029,0.00515054,0.260939 beta-lactamase_625_V78N,beta-lactamase_625_78,TEM-1,beta-lactamase_625,P62593,0.260947,NO,78,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.459,-4.189,2.73,,,H,A,0.44,-0.47,2.045,,63.64,HHH,-1.17833,0.213352,0.00492501,0.260947 kka2_1:4_R211D,kka2_1:4_211,Kka2,kka2_1:4,P00552,0.260978,NO,211,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-0.899,-3.783,2.884,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.168804,0.00204888,0.260978 kka2_1:1_A119D,kka2_1:1_119,Kka2,kka2_1:1,P00552,0.261003,NO,119,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.073,-3.713,2.64,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.520039,0.00441074,0.261003 kka2_1:2_W24E,kka2_1:2_24,Kka2,kka2_1:2,P00552,0.261119,NO,24,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-1.779,-4.036,2.257,,0.477,E,B,1.51,-0.21,2.666,,56.06,AHH,-2.24467,0.295029,0.00631564,0.261119 kka2_1:1_Y244V,kka2_1:1_244,Kka2,kka2_1:1,P00552,0.261133,NO,244,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-0.775,-3.332,2.557,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.520039,0.00453187,0.261133 kka2_1:2_R258I,kka2_1:2_258,Kka2,kka2_1:2,P00552,0.261163,NO,258,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.626,-3.905,2.279,,0.316,H,A,1.2,-0.85,7.485,7.485,53.03,HBH,-1.25933,0.295029,0.00983174,0.261163 beta-lactamase_2500_W208N,beta-lactamase_2500_208,TEM-1,beta-lactamase_2500,P62593,0.261191,NO,208,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-0.818,-4.348,3.53,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.361275,0.00126609,0.261191 kka2_1:1_R253V,kka2_1:1_253,Kka2,kka2_1:1,P00552,0.261231,NO,253,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.356,-3.689,2.333,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.520039,0.0144195,0.261231 beta-lactamase_625_A230T,beta-lactamase_625_230,TEM-1,beta-lactamase_625,P62593,0.26128,NO,230,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.154,-3.381,2.227,,0.01,E,B,0.46,-1.17,0.777,,50,HHA,-1.079,0.213352,0.00516841,0.26128 beta-lactamase_2500_D48W,beta-lactamase_2500_48,TEM-1,beta-lactamase_2500,P62593,0.26129,NO,48,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.101,-5.502,4.401,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.361275,0.0027273,0.26129 beta-lactamase_156_L120E,beta-lactamase_156_120,TEM-1,beta-lactamase_156,P62593,0.261306,NO,120,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.044,-3.83,2.786,,,H,A,0.55,-1.13,7.813,,64.69,AHO,-1.13633,0.111618,0.00143563,0.261306 kka2_1:1_F263K,kka2_1:1_263,Kka2,kka2_1:1,P00552,0.261311,NO,263,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-0.911,-3.934,3.023,,0.006,G,A,0.58,-0.12,2.284,,45.83,AHH,-0.92,0.520039,0.0172454,0.261311 kka2_1:1_R253N,kka2_1:1_253,Kka2,kka2_1:1,P00552,0.261409,NO,253,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.356,-3.661,2.305,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.520039,0.0144195,0.261409 kka2_1:1_Y218M,kka2_1:1_218,Kka2,kka2_1:1,P00552,0.261414,NO,218,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-1.438,-4.695,3.257,,0.122,H,A,1.25,-0.69,3.059,,56.06,BHP,-1.17533,0.520039,0.0126098,0.261414 beta-lactamase_2500_I261R,beta-lactamase_2500_261,TEM-1,beta-lactamase_2500,P62593,0.26145,NO,261,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.361275,0.0123091,0.26145 kka2_1:1_F48A,kka2_1:1_48,Kka2,kka2_1:1,P00552,0.261472,NO,48,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.453,-3.34,1.887,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.520039,0.00475422,0.261472 kka2_1:1_F48E,kka2_1:1_48,Kka2,kka2_1:1,P00552,0.261472,NO,48,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.453,-3.968,2.515,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.520039,0.00475422,0.261472 beta-lactamase_2500_S233M,beta-lactamase_2500_233,TEM-1,beta-lactamase_2500,P62593,0.261473,NO,233,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.886,-4.626,2.74,,0.016,E,B,0.27,-1.01,2.851,,77.62,BPO,-1.17267,0.361275,0.00311415,0.261473 kka2_1:1_A176C,kka2_1:1_176,Kka2,kka2_1:1,P00552,0.261482,NO,176,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.621,-4.973,3.352,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.520039,0.0083587,0.261482 beta-lactamase_156_R162P,beta-lactamase_156_162,TEM-1,beta-lactamase_156,P62593,0.261483,NO,162,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.016,-2.671,1.655,,0.124,S,B,1.2,-0.37,7.444,,64.69,ABH,-1.25,0.111618,0.000561334,0.261483 kka2_1:1_A215Q,kka2_1:1_215,Kka2,kka2_1:1,P00552,0.261483,NO,215,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.968,-3.954,2.986,,0.039,E,B,0.46,-0.59,0.754,,50.38,HHA,-1.00467,0.520039,0.00529129,0.261483 beta-lactamase_39_A246K,beta-lactamase_39_246,TEM-1,beta-lactamase_39,P62593,0.261569,NO,246,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.121,-3.849,1.728,,0.01,E,B,0.46,-1.01,1.331,,73.78,HHH,-1.55633,0.0495842,0.00569458,0.261569 kka2_1:4_D156I,kka2_1:4_156,Kka2,kka2_1:4,P00552,0.261578,NO,156,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.696,-4.017,2.321,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.168804,0.00926998,0.261578 kka2_1:2_I115Q,kka2_1:2_115,Kka2,kka2_1:2,P00552,0.261589,NO,115,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.606,-4.312,2.706,,0.105,H,A,0.48,-1.18,0.878,,65.53,PHH,-2.205,0.295029,0.00836567,0.261589 beta-lactamase_625_T187P,beta-lactamase_625_187,TEM-1,beta-lactamase_625,P62593,0.2616,NO,187,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.401,-3.906,2.505,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.213352,0.00491782,0.2616 kka2_1:2_W236D,kka2_1:2_236,Kka2,kka2_1:2,P00552,0.261634,NO,236,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-1.363,-4.158,2.795,,0.303,H,A,1.51,-0.76,5.58,,48.48,AHH,-1.81267,0.295029,0.0088796,0.261634 beta-lactamase_625_D129K,beta-lactamase_625_129,TEM-1,beta-lactamase_625,P62593,0.261657,NO,129,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.816,-3.42,2.604,,,,B,0.75,-0.69,0.171,,34.97,PAP,-0.818,0.213352,0.00109178,0.261657 kka2_1:2_L212I,kka2_1:2_212,Kka2,kka2_1:2,P00552,0.261696,NO,212,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.904,-3.012,2.108,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.295029,0.0031426,0.261696 beta-lactamase_39_W227E,beta-lactamase_39_227,TEM-1,beta-lactamase_39,P62593,0.261697,NO,227,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-0.982,-3.914,2.932,,0.272,,B,0.47,-0.29,1.37,,74.48,OHH,-1.595,0.0495842,0.00226019,0.261697 kka2_1:2_D250P,kka2_1:2_250,Kka2,kka2_1:2,P00552,0.261738,NO,250,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.015,-3.798,2.783,,0.274,.,b,0.75,-0.46,3.796,,51.89,OAP,-1.83933,0.295029,0.0177103,0.261738 kka2_1:2_A144R,kka2_1:2_144,Kka2,kka2_1:2,P00552,0.261856,NO,144,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.859,-3.85,2.991,,,H,A,0.46,0.21,6.844,,52.65,BHB,-1.72933,0.295029,0.00231095,0.261856 beta-lactamase_2500_A282P,beta-lactamase_2500_282,TEM-1,beta-lactamase_2500,P62593,0.261865,NO,282,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.361275,0.0449821,0.261865 kka2_1:1_L107E,kka2_1:1_107,Kka2,kka2_1:1,P00552,0.261901,NO,107,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.238,-3.847,2.609,,0.197,.,B,0.55,-1.1,3.542,,71.59,BHH,-2.143,0.520039,0.00561937,0.261901 beta-lactamase_156_T69F,beta-lactamase_156_69,TEM-1,beta-lactamase_156,P62593,0.261902,NO,69,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-0.973,-4.127,3.154,,,G,A,0.22,-1.24,4.194,,93.01,PPH,-1.01833,0.111618,0.00127498,0.261902 kka2_1:1_G164Q,kka2_1:1_164,Kka2,kka2_1:1,P00552,0.261966,NO,164,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.869,-4.074,3.205,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.520039,0.00442091,0.261966 kka2_1:2_I228P,kka2_1:2_228,Kka2,kka2_1:2,P00552,0.262011,NO,228,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.142,-4.165,3.023,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.295029,0.00458834,0.262011 beta-lactamase_2500_L219W,beta-lactamase_2500_219,TEM-1,beta-lactamase_2500,P62593,0.262082,NO,219,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.313,-5.183,3.87,,,I,A,0.55,-0.51,35.994,35.994,74.48,HHB,-1.21533,0.361275,0.00664345,0.262082 beta-lactamase_39_Y44N,beta-lactamase_39_44,TEM-1,beta-lactamase_39,P62593,0.262114,NO,44,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-2.547,-4.162,1.615,,,E,B,0.21,-0.45,2.683,,73.78,OHH,-1.86267,0.0495842,0.00426364,0.262114 kka2_1:2_S104E,kka2_1:2_104,Kka2,kka2_1:2,P00552,0.262139,NO,104,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.436,-2.627,1.191,,0.536,T,A,0.27,-1.11,5.49,,63.64,HPP,-1.91433,0.295029,0.00555207,0.262139 kka2_1:1_S32A,kka2_1:1_32,Kka2,kka2_1:1,P00552,0.26214,NO,32,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-0.804,-2.656,1.852,,0.768,S,b,0.27,3.75,,,,OPA,-1.74533,0.520039,0.00149998,0.26214 Pab1_G169V,Pab1_169,Pab1,Pab1,P04147,0.262243,NO,169,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.809,-3.571,2.762,,,E,b,0.35,0.03,,,,HOH,-1.11567,0.175299,0.000302434,0.262243 beta-lactamase_2500_D48R,beta-lactamase_2500_48,TEM-1,beta-lactamase_2500,P62593,0.262245,NO,48,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.101,-3.84,2.739,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.361275,0.0027273,0.262245 kka2_1:1_A117N,kka2_1:1_117,Kka2,kka2_1:1,P00552,0.262294,NO,117,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.828,-3.99,3.162,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.520039,0.00282984,0.262294 beta-lactamase_W286V,beta-lactamase_286,TEM-1,beta-lactamase,P62593,0.262363,NO,286,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-1.111,-3.571,2.46,6.64456,0.492,,?,0.01,0.6,,,,BHX,-1.478,0.221079,,0.262363 kka2_1:2_G189P,kka2_1:2_189,Kka2,kka2_1:2,P00552,0.26239,NO,189,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.596,-3.908,3.312,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.295029,0.00253688,0.26239 kka2_1:4_V185D,kka2_1:4_185,Kka2,kka2_1:4,P00552,0.262402,NO,185,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.045,-4.011,2.966,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.168804,0.00367031,0.262402 beta-lactamase_625_D155S,beta-lactamase_625_155,TEM-1,beta-lactamase_625,P62593,0.262424,NO,155,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.889,-3.185,2.296,,0.049,,B,0.75,-0.9,4.922,,64.69,OAB,-1.62267,0.213352,0.00135315,0.262424 kka2_1:2_F264H,kka2_1:2_264,Kka2,kka2_1:2,P00552,0.262426,NO,264,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.02,-4.405,3.385,,0.296,.,?,0.58,0.02,2.303,,71.59,HHNA,-0.9655,0.295029,,0.262426 beta-lactamase_2500_A124L,beta-lactamase_2500_124,TEM-1,beta-lactamase_2500,P62593,0.2625,NO,124,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.181,-3.172,1.991,,,H,A,0.46,-0.9,0.314,,64.34,HHH,-1.152,0.361275,0.00481399,0.2625 beta-lactamase_625_I229S,beta-lactamase_625_229,TEM-1,beta-lactamase_625,P62593,0.262563,NO,229,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.267,-3.615,2.348,,0.083,E,B,0.48,-0.76,1.69,,50,HHH,-1.58767,0.213352,0.00477249,0.262563 beta-lactamase_V72Q,beta-lactamase_72,TEM-1,beta-lactamase,P62593,0.262614,NO,72,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.658,-4.185,2.527,5.80324,,H,A,2.78,-1.03,2.964,,65.73,BHH,-1.32167,0.221079,0.00501194,0.262614 WW_domain_F189T,WW_domain_189,Yap65,WW_domain,P46937,0.262629,NO,189,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.632,-3.487,1.855,5.47284,,,,,,6.165,,56.94,HHH,-1.454,0.153962,0.00308453,0.262629 beta-lactamase_2500_G154W,beta-lactamase_2500_154,TEM-1,beta-lactamase_2500,P62593,0.262699,NO,154,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.823,-5.233,4.41,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.361275,0.00180205,0.262699 beta-lactamase_2500_T116W,beta-lactamase_2500_116,TEM-1,beta-lactamase_2500,P62593,0.26271,NO,116,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.28,-5.356,4.076,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.361275,0.00336175,0.26271 beta-lactamase_2500_I244H,beta-lactamase_2500_244,TEM-1,beta-lactamase_2500,P62593,0.262723,NO,244,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.555,-4.957,3.402,,,E,B,0.48,-0.84,1.683,,77.62,OHH,-1.385,0.361275,0.00605379,0.262723 kka2_1:1_I207C,kka2_1:1_207,Kka2,kka2_1:1,P00552,0.262736,NO,207,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.175,-4.752,3.577,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.520039,0.00611824,0.262736 kka2_1:4_I115E,kka2_1:4_115,Kka2,kka2_1:4,P00552,0.262774,NO,115,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.606,-3.967,2.361,,0.105,H,A,1.52,-1.18,9.996,9.996,65.53,PHH,-2.205,0.168804,0.00836567,0.262774 beta-lactamase_2500_D174Q,beta-lactamase_2500_174,TEM-1,beta-lactamase_2500,P62593,0.262787,NO,174,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.738,-3.674,2.936,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.361275,0.00125633,0.262787 beta-lactamase_L247E,beta-lactamase_247,TEM-1,beta-lactamase,P62593,0.262829,NO,247,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.48,-3.899,2.419,5.28771,0.007,E,B,2.89,-0.72,2.951,,63.99,HHO,-1.79833,0.221079,0.00611275,0.262829 beta-lactamase_625_I280A,beta-lactamase_625_280,TEM-1,beta-lactamase_625,P62593,0.262911,NO,280,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.708,-4.017,2.309,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.213352,0.0530888,0.262911 beta-lactamase_625_G154I,beta-lactamase_625_154,TEM-1,beta-lactamase_625,P62593,0.262948,NO,154,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.823,-4.173,3.35,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.213352,0.00180205,0.262948 beta-lactamase_2500_L136T,beta-lactamase_2500_136,TEM-1,beta-lactamase_2500,P62593,0.262976,NO,136,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.232,-3.487,2.255,,,H,A,0.55,-0.34,1.36,,48.95,HHH,-1.088,0.361275,0.00442304,0.262976 beta-lactamase_625_G249D,beta-lactamase_625_249,TEM-1,beta-lactamase_625,P62593,0.26302,NO,249,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.213352,0.00220169,0.26302 kka2_1:1_L47N,kka2_1:1_47,Kka2,kka2_1:1,P00552,0.263079,NO,47,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.265,-4.107,2.842,,0.139,E,B,0.55,-0.86,14.593,14.593,63.26,HHH,-1.77933,0.520039,0.00509386,0.263079 beta-lactamase_625_D129V,beta-lactamase_625_129,TEM-1,beta-lactamase_625,P62593,0.263104,NO,129,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.816,-3.751,2.935,,,,B,0.75,-0.69,0.171,,34.97,PAP,-0.818,0.213352,0.00109178,0.263104 beta-lactamase_625_W288G,beta-lactamase_625_288,TEM-1,beta-lactamase_625,P62593,0.263115,NO,288,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,,,,,,,,,,,,,BHO,,0.213352,,0.263115 kka2_1:4_E96W,kka2_1:4_96,Kka2,kka2_1:4,P00552,0.263161,NO,96,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.573,-5.436,2.863,,0.476,,B,1.52,-0.65,1.254,,71.59,OAH,-2.143,0.168804,0.00369441,0.263161 kka2_1:1_F263N,kka2_1:1_263,Kka2,kka2_1:1,P00552,0.263177,NO,263,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-0.911,-4.185,3.274,,0.006,G,A,0.58,-0.12,2.284,,45.83,AHH,-0.92,0.520039,0.0172454,0.263177 kka2_1:4_G245P,kka2_1:4_245,Kka2,kka2_1:4,P00552,0.263219,NO,245,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.812,-3.931,3.119,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.168804,0.00683899,0.263219 beta-lactamase_A230Q,beta-lactamase_230,TEM-1,beta-lactamase,P62593,0.263227,NO,230,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.154,-4.025,2.871,4.54336,0.01,E,B,0.75,-1.17,1.97,,50,HHA,-1.079,0.221079,0.00516841,0.263227 kka2_1:4_F171K,kka2_1:4_171,Kka2,kka2_1:4,P00552,0.263236,NO,171,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.326,-3.945,2.619,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.168804,0.00821426,0.263236 kka2_1:4_F37I,kka2_1:4_37,Kka2,kka2_1:4,P00552,0.263251,NO,37,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.427,-3.594,2.167,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.168804,0.00586193,0.263251 kka2_1:4_L174H,kka2_1:4_174,Kka2,kka2_1:4,P00552,0.263269,NO,174,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.952,-4.968,4.016,,,H,A,0.55,-0.31,1.339,,51.89,BHB,-2.08533,0.168804,0.00438501,0.263269 kka2_1:1_A117C,kka2_1:1_117,Kka2,kka2_1:1,P00552,0.263297,NO,117,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.828,-4.504,3.676,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.520039,0.00282984,0.263297 beta-lactamase_625_I229W,beta-lactamase_625_229,TEM-1,beta-lactamase_625,P62593,0.263299,NO,229,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.267,-5.365,4.098,,0.083,E,B,0.48,-0.76,1.69,,50,HHH,-1.58767,0.213352,0.00477249,0.263299 kka2_1:1_T72L,kka2_1:1_72,Kka2,kka2_1:1,P00552,0.263365,NO,72,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.38,-3.619,1.239,,0.784,H,A,0.22,0.29,10.43,10.43,65.53,HPP,-2.238,0.520039,0.00750756,0.263365 hsp90_W585Q,hsp90_585,hsp90,hsp90,P02829,0.263421,NO,585,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-4.251,-3.278,0,5.31455,0.508,,B,1.22,0.43,,,,OHP,-3.17533,0.368192,0.000222939,0.263421 kka2_1:1_A117L,kka2_1:1_117,Kka2,kka2_1:1,P00552,0.263444,NO,117,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.828,-3.117,2.289,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.520039,0.00282984,0.263444 beta-lactamase_M1F,beta-lactamase_1,TEM-1,beta-lactamase,P62593,0.263449,NO,1,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.998,-3.299,1.301,,,,,,,,,,OHP,-1.97,0.221079,0.00162771,0.263449 beta-lactamase_2500_L120S,beta-lactamase_2500_120,TEM-1,beta-lactamase_2500,P62593,0.26348,NO,120,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.044,-3.66,2.616,,,H,A,0.55,-1.13,2.48,,64.69,AHO,-1.13633,0.361275,0.00143563,0.26348 beta-lactamase_2500_N274I,beta-lactamase_2500_274,TEM-1,beta-lactamase_2500,P62593,0.263483,NO,274,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.361275,0.0110418,0.263483 beta-lactamase_625_G236F,beta-lactamase_625_236,TEM-1,beta-lactamase_625,P62593,0.263506,NO,236,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.784,-4.291,3.507,,0.241,,b,0.29,-0.59,3.506,,64.69,HOO,-1.025,0.213352,0.00162372,0.263506 kka2_1:1_V49D,kka2_1:1_49,Kka2,kka2_1:1,P00552,0.263585,NO,49,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.614,-4.094,2.48,,,E,B,0.44,-0.77,3.665,3.665,64.39,HHB,-1.3,0.520039,0.00615685,0.263585 Pab1_N127T,Pab1_127,Pab1,Pab1,P04147,0.263622,NO,127,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-1.079,-3.014,1.935,,0.138,E,B,1.05,-0.51,,,,OPH,-1.13633,0.175299,0.000805159,0.263622 kka2_1:2_F263R,kka2_1:2_263,Kka2,kka2_1:2,P00552,0.263643,NO,263,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-0.911,-4.185,3.274,,0.006,G,A,1.62,-0.12,5.275,,45.83,AHH,-0.92,0.295029,0.0172454,0.263643 kka2_1:1_R18F,kka2_1:1_18,Kka2,kka2_1:1,P00552,0.263645,NO,18,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.055,-3.418,1.363,,0.474,T,A,1.2,0.54,11.422,11.422,71.59,ABH,-1.821,0.520039,0.00724065,0.263645 beta-lactamase_625_I258S,beta-lactamase_625_258,TEM-1,beta-lactamase_625,P62593,0.263647,NO,258,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.213352,0.007931,0.263647 kka2_1:1_A224F,kka2_1:1_224,Kka2,kka2_1:1,P00552,0.263668,NO,224,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.977,-4.161,3.184,,,H,A,0.46,-1.26,1.725,,63.64,HHP,-1.41033,0.520039,0.00352047,0.263668 kka2_1:1_E235P,kka2_1:1_235,Kka2,kka2_1:1,P00552,0.263691,NO,235,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.955,-2.919,0.964,,0.631,H,A,1.52,0.12,8.521,,65.53,OAH,-2.07267,0.520039,0.0102806,0.263691 beta-lactamase_625_A124D,beta-lactamase_625_124,TEM-1,beta-lactamase_625,P62593,0.263723,NO,124,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.181,-3.709,2.528,,,H,A,0.46,-0.9,2.027,,64.34,HHH,-1.152,0.213352,0.00481399,0.263723 kka2_1:4_D250W,kka2_1:4_250,Kka2,kka2_1:4,P00552,0.263783,NO,250,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.015,-5.585,4.57,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.168804,0.0177103,0.263783 beta-lactamase_625_R257W,beta-lactamase_625_257,TEM-1,beta-lactamase_625,P62593,0.263802,NO,257,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.213352,0.00756629,0.263802 kka2_1:2_V113C,kka2_1:2_113,Kka2,kka2_1:2,P00552,0.263887,NO,113,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.233,-4.781,3.548,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.295029,0.00650191,0.263887 beta-lactamase_0_T107N,beta-lactamase_0_107,TEM-1,beta-lactamase_0,P62593,0.263916,NO,107,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.117,-3.473,2.356,,,G,A,0.22,-0.06,3.73,,67.83,HPA,-1.265,0.0500837,0.00239347,0.263916 beta-lactamase_625_L79N,beta-lactamase_625_79,TEM-1,beta-lactamase_625,P62593,0.263948,NO,79,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.842,-4.12,3.278,,0.007,H,A,0.55,-0.16,0.935,,50.35,HHP,-1.44333,0.213352,0.000947397,0.263948 kka2_1:2_A119Q,kka2_1:2_119,Kka2,kka2_1:2,P00552,0.263964,NO,119,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.073,-4.017,2.944,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.295029,0.00441074,0.263964 beta-lactamase_2500_S104D,beta-lactamase_2500_104,TEM-1,beta-lactamase_2500,P62593,0.26401,NO,104,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.015,-3.41,2.395,,0.04,,b,0.27,0.57,1.133,,63.29,HPO,-1.05267,0.361275,0.00218083,0.26401 kka2_1:1_G95H,kka2_1:1_95,Kka2,kka2_1:1,P00552,0.264045,NO,95,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-2.403,-4.673,2.27,,0.126,E,B,0.29,-0.74,7.822,,71.59,HOA,-2.198,0.520039,0.00743616,0.264045 beta-lactamase_F70R,beta-lactamase_70,TEM-1,beta-lactamase,P62593,0.264088,NO,70,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.169,-4.114,2.945,5.42055,,H,A,1.1,-1.34,1.14,,63.99,PHB,-0.980667,0.221079,0.00193499,0.264088 kka2_1:4_K112H,kka2_1:4_112,Kka2,kka2_1:4,P00552,0.26421,NO,112,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-2.491,-4.863,2.372,,0.076,H,A,2.34,-1.37,0.39,,56.06,ABH,-2.00133,0.168804,0.00645389,0.26421 kka2_1:1_D216H,kka2_1:1_216,Kka2,kka2_1:1,P00552,0.264252,NO,216,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.785,-2.903,2.118,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.520039,0.00229969,0.264252 kka2_1:1_L107W,kka2_1:1_107,Kka2,kka2_1:1,P00552,0.264321,NO,107,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.238,-5.321,4.083,,0.197,.,B,0.55,-1.1,3.542,,71.59,BHH,-2.143,0.520039,0.00561937,0.264321 beta-lactamase_2500_T27N,beta-lactamase_2500_27,TEM-1,beta-lactamase_2500,P62593,0.264338,NO,27,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.905,-2.525,0.62,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.361275,0.00306559,0.264338 kka2_1:1_V186E,kka2_1:1_186,Kka2,kka2_1:1,P00552,0.264351,NO,186,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.011,-3.841,2.83,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.520039,0.00409703,0.264351 kka2_1:1_G164L,kka2_1:1_164,Kka2,kka2_1:1,P00552,0.264398,NO,164,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.869,-3.829,2.96,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.520039,0.00442091,0.264398 hsp90_A587H,hsp90_587,hsp90,hsp90,P02829,0.264406,NO,587,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.456,-3.833,0,4.91216,0.049,H,A,0.55,-0.02,,,,PHP,-2.757,0.368192,0.000222939,0.264406 kka2_1:1_P132V,kka2_1:1_132,Kka2,kka2_1:1,P00552,0.264409,NO,132,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.775,-3.58,2.805,,0.692,.,A,0.52,0.56,0.224,,44.7,OOH,-0.825667,0.520039,0.0018489,0.264409 kka2_1:1_N195W,kka2_1:1_195,Kka2,kka2_1:1,P00552,0.264429,NO,195,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-0.836,-5.599,4.763,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.520039,0.00276134,0.264429 kka2_1:2_G245D,kka2_1:2_245,Kka2,kka2_1:2,P00552,0.264447,NO,245,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.812,-3.456,2.644,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.295029,0.00683899,0.264447 beta-lactamase_2500_I285N,beta-lactamase_2500_285,TEM-1,beta-lactamase_2500,P62593,0.264467,NO,285,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.361275,0.101555,0.264467 kka2_1:1_P12F,kka2_1:1_12,Kka2,kka2_1:1,P00552,0.264502,NO,12,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.853,-4.467,3.614,,,.,B,0.52,1.25,0.261,,48.11,POH,-1.80767,0.520039,0.00500011,0.264502 kka2_1:1_R211K,kka2_1:1_211,Kka2,kka2_1:1,P00552,0.264504,NO,211,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-0.899,-2.904,2.005,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.520039,0.00204888,0.264504 PSD95pdz3_G330V,PSD95pdz3_330,PSD95pdz3,PSD95pdz3,P31016,0.264534,NO,330,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.008,-3.435,2.427,4.68351,,,,,31.405,,,,OOA,-1.14,0.0758425,0.000962386,0.264534 beta-lactamase_2500_M209Q,beta-lactamase_2500_209,TEM-1,beta-lactamase_2500,P62593,0.264546,NO,209,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.442,-3.974,2.532,,,H,A,0.55,-0.97,3.229,,64.69,HHA,-1.52633,0.361275,0.00625021,0.264546 kka2_1:4_V186E,kka2_1:4_186,Kka2,kka2_1:4,P00552,0.264601,NO,186,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.011,-3.841,2.83,,,E,B,0.44,-0.61,0.679,,45.83,HHP,-1.10967,0.168804,0.00409703,0.264601 kka2_1:2_M148N,kka2_1:2_148,Kka2,kka2_1:2,P00552,0.264631,NO,148,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.847,-4.17,2.323,,0.268,H,A,1.59,0.71,1.439,,64.39,BHA,-1.65467,0.295029,0.00982664,0.264631 beta-lactamase_156_L137K,beta-lactamase_156_137,TEM-1,beta-lactamase_156,P62593,0.264644,NO,137,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.03,-3.749,2.719,,,H,A,0.55,-0.38,0.674,,42.31,HHP,-1.58933,0.111618,0.00278599,0.264644 kka2_1:4_Y257L,kka2_1:4_257,Kka2,kka2_1:4,P00552,0.264663,NO,257,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-1.064,-3.141,2.077,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.168804,0.0148191,0.264663 kka2_1:8_M116G,kka2_1:8_116,Kka2,kka2_1:8,P00552,0.264685,NO,116,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-2.482,-3.754,1.272,,,H,A,1.59,-0.88,4.659,,71.59,HHH,-1.63867,0.100394,0.00745147,0.264685 kka2_1:8_M116G,kka2_1:8_116,Kka2,kka2_1:8,P00552,0.264685,NO,116,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-2.482,-3.754,1.272,,,H,A,1.59,-0.88,4.659,,71.59,HHH,-1.63867,0.100394,0.00745147,0.264685 kka2_1:1_G210Y,kka2_1:1_210,Kka2,kka2_1:1,P00552,0.264712,NO,210,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.095,-4.42,3.325,,0.103,T,A,0.29,-0.62,14.483,14.483,50,OOB,-0.966667,0.520039,0.00598378,0.264712 beta-lactamase_156_I229D,beta-lactamase_156_229,TEM-1,beta-lactamase_156,P62593,0.26477,NO,229,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.267,-3.973,2.706,,0.083,E,B,0.48,-0.76,1.114,,50,HHH,-1.58767,0.111618,0.00477249,0.26477 beta-lactamase_39_A133K,beta-lactamase_39_133,TEM-1,beta-lactamase_39,P62593,0.264809,NO,133,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.186,-3.614,2.428,,,H,A,0.46,-0.86,0.373,,67.83,HHP,-0.988333,0.0495842,0.00468022,0.264809 beta-lactamase_2500_G226V,beta-lactamase_2500_226,TEM-1,beta-lactamase_2500,P62593,0.264897,NO,226,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.461,-3.807,2.346,,0.701,T,l,0.29,-0.25,5.086,,74.48,HOH,-1.42933,0.361275,0.00665294,0.264897 beta-lactamase_D177A,beta-lactamase_177,TEM-1,beta-lactamase,P62593,0.264942,NO,177,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.967,-2.529,1.562,5.08038,0.006,T,L,1.59,-1.02,3.536,,64.69,BAP,-0.873667,0.221079,0.000864022,0.264942 beta-lactamase_2500_E87P,beta-lactamase_2500_87,TEM-1,beta-lactamase_2500,P62593,0.264982,NO,87,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.421,-3.872,2.451,,0.048,,B,1.04,0.92,17.923,17.923,64.69,PAP,-1.969,0.361275,0.00337888,0.264982 kka2_1:2_D101R,kka2_1:2_101,Kka2,kka2_1:2,P00552,0.264986,NO,101,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.028,-3.968,2.94,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.295029,0.00423361,0.264986 beta-lactamase_A185L,beta-lactamase_185,TEM-1,beta-lactamase,P62593,0.265046,NO,185,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.406,-2.064,0.658,4.89877,,H,A,2.34,-1.02,2.999,,65.03,HHP,-1.84033,0.221079,0.00467449,0.265046 kka2_1:1_V97Q,kka2_1:1_97,Kka2,kka2_1:1,P00552,0.265073,NO,97,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.453,-4.252,2.799,,0.083,,B,1.48,-0.83,13.576,13.576,53.03,AHO,-1.85067,0.520039,0.00737869,0.265073 kka2_1:1_K175P,kka2_1:1_175,Kka2,kka2_1:1,P00552,0.265099,NO,175,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-2.897,-4.168,1.271,,0.579,H,A,1.3,0.51,9.33,9.33,71.59,HBH,-1.82333,0.520039,0.00693093,0.265099 kka2_1:1_E161L,kka2_1:1_161,Kka2,kka2_1:1,P00552,0.265116,NO,161,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.581,-3.558,1.977,,0.829,G,A,1.04,2.24,1.612,,92.05,AAB,-1.861,0.520039,0.00760103,0.265116 kka2_1:1_G30I,kka2_1:1_30,Kka2,kka2_1:1,P00552,0.265116,NO,30,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.596,-4.264,3.668,,0.54,S,g,0.29,3.76,,,,HOO,-1.51133,0.520039,0.00159208,0.265116 kka2_1:2_C209H,kka2_1:2_209,Kka2,kka2_1:2,P00552,0.265116,NO,209,C,H,CH,Special,PositiveCharge,5.07,7.59,2.52,174,121,155,34,108.5,153.2,44.7,-0.906,-4.957,4.051,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.295029,0.00260862,0.265116 kka2_1:1_E231N,kka2_1:1_231,Kka2,kka2_1:1,P00552,0.265131,NO,231,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.002,-1.271,-0.731,,0.503,H,A,1.04,-0.23,25.629,25.629,63.26,AAH,-2.06267,0.520039,0.00732383,0.265131 kka2_1:1_L260C,kka2_1:1_260,Kka2,kka2_1:1,P00552,0.265149,NO,260,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.741,-4.665,3.924,,0.022,H,A,0.55,-0.52,,,,HHA,-0.845667,0.520039,0.0233782,0.265149 kka2_1:4_L259D,kka2_1:4_259,Kka2,kka2_1:4,P00552,0.265224,NO,259,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.088,-4.066,2.978,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.168804,0.0206964,0.265224 kka2_1:1_D90F,kka2_1:1_90,Kka2,kka2_1:1,P00552,0.26523,NO,90,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.459,-3.305,0.846,,0.104,E,B,0.75,0.73,6.085,,64.39,BAH,-1.72833,0.520039,0.00583842,0.26523 beta-lactamase_625_Q203P,beta-lactamase_625_203,TEM-1,beta-lactamase_625,P62593,0.265267,NO,203,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.168,-3.941,1.773,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.213352,0.00631514,0.265267 kka2_1:1_D190P,kka2_1:1_190,Kka2,kka2_1:1,P00552,0.265267,NO,190,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.708,-3.683,2.975,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.520039,0.00247989,0.265267 kka2_1:1_L170K,kka2_1:1_170,Kka2,kka2_1:1,P00552,0.265298,NO,170,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.28,-3.796,2.516,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.520039,0.00730791,0.265298 kka2_1:4_A144R,kka2_1:4_144,Kka2,kka2_1:4,P00552,0.265361,NO,144,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.859,-3.85,2.991,,,H,A,0.46,0.21,6.844,,52.65,BHB,-1.72933,0.168804,0.00231095,0.265361 kka2_1:2_P12H,kka2_1:2_12,Kka2,kka2_1:2,P00552,0.26539,NO,12,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.853,-4.718,3.865,,,.,B,0.52,1.25,0.261,,48.11,POH,-1.80767,0.295029,0.00500011,0.26539 kka2_1:4_L170T,kka2_1:4_170,Kka2,kka2_1:4,P00552,0.265434,NO,170,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.28,-3.474,2.194,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.168804,0.00730791,0.265434 kka2_1:2_F264A,kka2_1:2_264,Kka2,kka2_1:2,P00552,0.265516,NO,264,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.02,-3.385,2.365,,0.296,.,?,0.58,0.02,2.303,,71.59,HHNA,-0.9655,0.295029,,0.265516 kka2_1:4_V97W,kka2_1:4_97,Kka2,kka2_1:4,P00552,0.265553,NO,97,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.453,-5.36,3.907,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.168804,0.00737869,0.265553 kka2_1:1_A237C,kka2_1:1_237,Kka2,kka2_1:1,P00552,0.26556,NO,237,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.12,-4.796,2.676,,0.068,H,A,0.46,-0.71,2.369,,92.05,HHA,-2.10433,0.520039,0.012257,0.26556 kka2_1:1_A237I,kka2_1:1_237,Kka2,kka2_1:1,P00552,0.26556,NO,237,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.12,-2.296,0.176,,0.068,H,A,0.46,-0.71,2.369,,92.05,HHA,-2.10433,0.520039,0.012257,0.26556 kka2_1:1_A237R,kka2_1:1_237,Kka2,kka2_1:1,P00552,0.26556,NO,237,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.12,-4.175,2.055,,0.068,H,A,0.46,-0.71,2.369,,92.05,HHA,-2.10433,0.520039,0.012257,0.26556 kka2_1:2_F206P,kka2_1:2_206,Kka2,kka2_1:2,P00552,0.265585,NO,206,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.349,-4.311,2.962,,0.006,E,B,0.58,-1.21,0.978,,63.64,OHH,-1.04,0.295029,0.00936868,0.265585 beta-lactamase_R59I,beta-lactamase_59,TEM-1,beta-lactamase,P62593,0.265621,NO,59,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.345,-4.065,2.72,5.49837,0.329,S,L,0.68,-0.09,1.806,,73.08,HBO,-2.24267,0.221079,0.00318082,0.265621 beta-lactamase_2500_A230W,beta-lactamase_2500_230,TEM-1,beta-lactamase_2500,P62593,0.265624,NO,230,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.154,-5.319,4.165,,0.01,E,B,0.46,-1.17,1.171,,50,HHA,-1.079,0.361275,0.00516841,0.265624 kka2_1:4_E96I,kka2_1:4_96,Kka2,kka2_1:4,P00552,0.26563,NO,96,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.573,-3.722,1.149,,0.476,,B,1.52,-0.65,1.254,,71.59,OAH,-2.143,0.168804,0.00369441,0.26563 kka2_1:2_I115P,kka2_1:2_115,Kka2,kka2_1:2,P00552,0.265644,NO,115,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.606,-4.209,2.603,,0.105,H,A,0.48,-1.18,0.878,,65.53,PHH,-2.205,0.295029,0.00836567,0.265644 kka2_1:1_L193A,kka2_1:1_193,Kka2,kka2_1:1,P00552,0.265678,NO,193,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.983,-3.189,2.206,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.520039,0.00480179,0.265678 kka2_1:1_I228G,kka2_1:1_228,Kka2,kka2_1:1,P00552,0.265684,NO,228,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.142,-3.869,2.727,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.520039,0.00458834,0.265684 kka2_1:2_A117L,kka2_1:2_117,Kka2,kka2_1:2,P00552,0.265717,NO,117,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.828,-3.117,2.289,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.295029,0.00282984,0.265717 kka2_1:1_H162K,kka2_1:1_162,Kka2,kka2_1:1,P00552,0.265752,NO,162,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-2.319,-3.151,0.832,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.520039,0.00616145,0.265752 kka2_1:1_R38M,kka2_1:1_38,Kka2,kka2_1:1,P00552,0.265753,NO,38,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.207,-3.078,1.871,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.520039,0.00372499,0.265753 kka2_1:4_L241H,kka2_1:4_241,Kka2,kka2_1:4,P00552,0.26576,NO,241,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.158,-4.825,3.667,,0.08,H,A,0.55,-0.82,1.598,,63.26,HHH,-1.58533,0.168804,0.0117299,0.26576 beta-lactamase_2500_A230F,beta-lactamase_2500_230,TEM-1,beta-lactamase_2500,P62593,0.265792,NO,230,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.154,-4.217,3.063,,0.01,E,B,0.46,-1.17,1.171,,50,HHA,-1.079,0.361275,0.00516841,0.265792 kka2_1:1_L94S,kka2_1:1_94,Kka2,kka2_1:1,P00552,0.265812,NO,94,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.618,-3.596,1.978,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.520039,0.00520888,0.265812 kka2_1:1_L102F,kka2_1:1_102,Kka2,kka2_1:1,P00552,0.265865,NO,102,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.804,-3.669,2.865,,,T,A,0.55,-1.17,4.258,,42.42,AHH,-1.398,0.520039,0.00201332,0.265865 kka2_1:4_L67D,kka2_1:4_67,Kka2,kka2_1:4,P00552,0.265934,NO,67,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.741,-4.172,3.431,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.168804,0.00102787,0.265934 beta-lactamase_625_V260W,beta-lactamase_625_260,TEM-1,beta-lactamase_625,P62593,0.265967,NO,260,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.213352,0.00471757,0.265967 beta-lactamase_2500_A123E,beta-lactamase_2500_123,TEM-1,beta-lactamase_2500,P62593,0.265998,NO,123,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.834,-3.489,2.655,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.361275,0.0010157,0.265998 kka2_1:2_A34C,kka2_1:2_34,Kka2,kka2_1:2,P00552,0.266083,NO,34,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.928,-4.523,3.595,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.295029,0.00343484,0.266083 kka2_1:2_A215Y,kka2_1:2_215,Kka2,kka2_1:2,P00552,0.266092,NO,215,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.968,-4.276,3.308,,0.039,E,B,0.46,-0.59,2.137,,50.38,HHA,-1.00467,0.295029,0.00529129,0.266092 kka2_1:4_D101K,kka2_1:4_101,Kka2,kka2_1:4,P00552,0.266118,NO,101,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.028,-3.563,2.535,,0.213,E,B,0.75,-1.24,8.707,,63.64,PAH,-1.534,0.168804,0.00423361,0.266118 Ubiquitin_G75K,Ubiquitin_75,Uba1,Ubiquitin,P0CG48,0.266129,NO,75,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.613,-3.667,2.054,5.44099,0.552,T,A,0.73,0.9,4.017,,34.31,BOO,-1.66767,0.205827,0.000712673,0.266129 Ubiquitin_H68P,Ubiquitin_68,Uba1,Ubiquitin,P0CG48,0.266129,NO,68,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-1.869,-3.027,1.158,4.81902,0.194,E,B,0.72,-1.02,21.325,21.325,65.11,HBH,-1.583,0.205827,0.000925438,0.266129 Ubiquitin_K48D,Ubiquitin_48,Uba1,Ubiquitin,P0CG48,0.266129,NO,48,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.436,-3.476,2.04,5.03072,0.132,E,B,2.92,-0.28,1.539,,53.87,OBP,-1.6,0.205827,0.000394633,0.266129 Ubiquitin_L69Q,Ubiquitin_69,Uba1,Ubiquitin,P0CG48,0.266129,NO,69,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.445,-3.032,1.587,4.75624,0.051,E,B,2.89,-0.94,7.106,,34.31,BHH,-1.72933,0.205827,0.000919136,0.266129 Ubiquitin_Q2A,Ubiquitin_2,Uba1,Ubiquitin,P0CG48,0.266129,NO,2,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-1.7,-3.141,1.441,4.89203,0.475,E,B,,0.1,,,,OPH,-1.551,0.205827,0.00085006,0.266129 Ubiquitin_V5G,Ubiquitin_5,Uba1,Ubiquitin,P0CG48,0.266129,NO,5,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.576,-3.515,1.939,4.75677,,E,B,,-0.82,,,,HHB,-1.401,0.205827,0.000796998,0.266129 Ubiquitin_V70R,Ubiquitin_70,Uba1,Ubiquitin,P0CG48,0.266129,NO,70,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.874,-4.04,2.166,5.29728,0.05,E,B,0.96,-0.97,2.363,,34.31,HHH,-1.65533,0.205827,0.00106871,0.266129 beta-lactamase_625_A282P,beta-lactamase_625_282,TEM-1,beta-lactamase_625,P62593,0.266183,NO,282,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.213352,0.0449821,0.266183 beta-lactamase_39_C121Y,beta-lactamase_39_121,TEM-1,beta-lactamase_39,P62593,0.266222,NO,121,C,Y,CY,Special,Hydrophobic,5.07,5.66,0.59,194,121,181,60,108.5,193.6,85.1,-0.953,-4.188,3.235,,,H,A,0.46,-0.81,7.644,,63.29,HOP,-1.46767,0.0495842,0.000744322,0.266222 kka2_1:1_A222K,kka2_1:1_222,Kka2,kka2_1:1,P00552,0.266227,NO,222,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.725,-3.485,2.76,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.520039,0.00207657,0.266227 kka2_1:2_V214N,kka2_1:2_214,Kka2,kka2_1:2,P00552,0.266295,NO,214,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.261,-4.229,2.968,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.295029,0.00692782,0.266295 kka2_1:2_V185S,kka2_1:2_185,Kka2,kka2_1:2,P00552,0.266329,NO,185,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.045,-3.595,2.55,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.295029,0.00367031,0.266329 beta-lactamase_2500_G234Q,beta-lactamase_2500_234,TEM-1,beta-lactamase_2500,P62593,0.266334,NO,234,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.62,-4.124,3.504,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.361275,0.000889577,0.266334 beta-lactamase_39_V72K,beta-lactamase_39_72,TEM-1,beta-lactamase_39,P62593,0.266343,NO,72,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.658,-3.754,2.096,,,H,A,0.44,-1.03,1.92,,65.73,BHH,-1.32167,0.0495842,0.00501194,0.266343 beta-lactamase_2500_L248R,beta-lactamase_2500_248,TEM-1,beta-lactamase_2500,P62593,0.266373,NO,248,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.361275,0.00428493,0.266373 kka2_1:8_M116D,kka2_1:8_116,Kka2,kka2_1:8,P00552,0.266378,NO,116,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-2.482,-4.161,1.679,,,H,A,1.59,-0.88,4.659,,71.59,HHH,-1.63867,0.100394,0.00745147,0.266378 kka2_1:8_M116D,kka2_1:8_116,Kka2,kka2_1:8,P00552,0.266378,NO,116,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-2.482,-4.161,1.679,,,H,A,1.59,-0.88,4.659,,71.59,HHH,-1.63867,0.100394,0.00745147,0.266378 kka2_1:2_L259Q,kka2_1:2_259,Kka2,kka2_1:2,P00552,0.266379,NO,259,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.088,-4.124,3.036,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.295029,0.0206964,0.266379 kka2_1:1_R143N,kka2_1:1_143,Kka2,kka2_1:1,P00552,0.266395,NO,143,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.525,-3.927,1.402,,0.325,H,A,0.16,1.22,3.6,,65.53,ABH,-1.86833,0.520039,0.00662247,0.266395 beta-lactamase_625_V42H,beta-lactamase_625_42,TEM-1,beta-lactamase_625,P62593,0.266422,NO,42,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.564,-4.991,3.427,,0.017,E,B,0.44,-0.51,2.576,,63.99,BHO,-1.042,0.213352,0.00404515,0.266422 beta-lactamase_2500_T69M,beta-lactamase_2500_69,TEM-1,beta-lactamase_2500,P62593,0.266431,NO,69,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-0.973,-4.54,3.567,,,G,A,0.22,-1.24,2.05,,93.01,PPH,-1.01833,0.361275,0.00127498,0.266431 beta-lactamase_625_L146S,beta-lactamase_625_146,TEM-1,beta-lactamase_625,P62593,0.266437,NO,146,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.462,-2.916,1.454,,0.007,H,A,0.55,-0.56,2.16,,64.69,AHP,-1.656,0.213352,0.00474542,0.266437 beta-lactamase_625_I125Q,beta-lactamase_625_125,TEM-1,beta-lactamase_625,P62593,0.266442,NO,125,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.441,-4.226,2.785,,,H,A,0.48,-0.7,2.034,,63.29,HHP,-1.248,0.213352,0.00383964,0.266442 kka2_1:1_P12E,kka2_1:1_12,Kka2,kka2_1:1,P00552,0.266492,NO,12,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.853,-3.478,2.625,,,.,B,0.52,1.25,0.261,,48.11,POH,-1.80767,0.520039,0.00500011,0.266492 kka2_1:2_D227M,kka2_1:2_227,Kka2,kka2_1:2,P00552,0.266506,NO,227,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.758,-4.662,2.904,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.295029,0.00745029,0.266506 kka2_1:8_V186K,kka2_1:8_186,Kka2,kka2_1:8,P00552,0.266531,NO,186,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.011,-3.841,2.83,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.100394,0.00409703,0.266531 kka2_1:8_V186K,kka2_1:8_186,Kka2,kka2_1:8,P00552,0.266531,NO,186,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.011,-3.841,2.83,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.100394,0.00409703,0.266531 kka2_1:1_E230F,kka2_1:1_230,Kka2,kka2_1:1,P00552,0.266608,NO,230,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.672,-3.006,0.334,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.520039,0.00920051,0.266608 beta-lactamase_2500_G114V,beta-lactamase_2500_114,TEM-1,beta-lactamase_2500,P62593,0.266619,NO,114,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.094,-3.65,2.556,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.361275,0.00224919,0.266619 beta-lactamase_625_S233V,beta-lactamase_625_233,TEM-1,beta-lactamase_625,P62593,0.266652,NO,233,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.886,-3.357,1.471,,0.016,E,B,0.27,-1.01,1.773,,77.62,BPO,-1.17267,0.213352,0.00311415,0.266652 kka2_1:8_P194K,kka2_1:8_194,Kka2,kka2_1:8,P00552,0.266685,NO,194,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.846,-3.507,2.661,,0.308,G,A,0.52,-1.19,4.861,,53.03,HOP,-0.888333,0.100394,0.00314194,0.266685 kka2_1:8_P194K,kka2_1:8_194,Kka2,kka2_1:8,P00552,0.266685,NO,194,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.846,-3.507,2.661,,0.308,G,A,0.52,-1.19,4.861,,53.03,HOP,-0.888333,0.100394,0.00314194,0.266685 kka2_1:1_R173P,kka2_1:1_173,Kka2,kka2_1:1,P00552,0.266715,NO,173,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.407,-4.037,1.63,,0.308,H,A,0.16,-0.13,14.756,14.756,65.53,HBH,-1.70533,0.520039,0.00784999,0.266715 kka2_1:2_Y22N,kka2_1:2_22,Kka2,kka2_1:2,P00552,0.266721,NO,22,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-1.583,-3.898,2.315,,0.122,.,B,0.21,-0.8,1.838,,65.53,OHA,-1.80333,0.295029,0.00598977,0.266721 kka2_1:8_R226I,kka2_1:8_226,Kka2,kka2_1:8,P00552,0.266765,NO,226,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.392,-4.182,2.79,,0.222,H,A,0.16,-0.71,3.818,,56.06,PBA,-1.84767,0.100394,0.0108032,0.266765 kka2_1:8_R226I,kka2_1:8_226,Kka2,kka2_1:8,P00552,0.266765,NO,226,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.392,-4.182,2.79,,0.222,H,A,0.16,-0.71,3.818,,56.06,PBA,-1.84767,0.100394,0.0108032,0.266765 kka2_1:1_A110I,kka2_1:1_110,Kka2,kka2_1:1,P00552,0.266783,NO,110,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.064,-3.899,1.835,,0.175,H,A,1.04,-1.19,11.755,,71.59,OHA,-1.91867,0.520039,0.00759851,0.266783 Pab1_I152S,Pab1_152,Pab1,Pab1,P04147,0.266787,NO,152,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.345,-3.503,2.158,,0.165,E,B,1.23,-0.71,1.288,,71.4,AHH,-1.59433,0.175299,0.000740963,0.266787 hsp90_M589N,hsp90_589,hsp90,hsp90,P02829,0.266808,NO,589,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-3.858,-3.051,0,4.72723,0.032,H,A,0.84,0.31,,,,PHA,-3.24233,0.368192,0.000222939,0.266808 kka2_1:2_L170W,kka2_1:2_170,Kka2,kka2_1:2,P00552,0.26685,NO,170,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.28,-5.33,4.05,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.295029,0.00730791,0.26685 beta-lactamase_625_S128K,beta-lactamase_625_128,TEM-1,beta-lactamase_625,P62593,0.26687,NO,128,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-0.84,-3.232,2.392,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.213352,0.00071483,0.26687 beta-lactamase_39_D129K,beta-lactamase_39_129,TEM-1,beta-lactamase_39,P62593,0.266896,NO,129,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.816,-3.42,2.604,,,,B,0.75,-0.69,0.56,,34.97,PAP,-0.818,0.0495842,0.00109178,0.266896 beta-lactamase_2500_L248E,beta-lactamase_2500_248,TEM-1,beta-lactamase_2500,P62593,0.266906,NO,248,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.361275,0.00428493,0.266906 kka2_1:1_G99T,kka2_1:1_99,Kka2,kka2_1:1,P00552,0.26691,NO,99,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.596,-3.675,3.079,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.520039,0.00186055,0.26691 beta-lactamase_156_L205N,beta-lactamase_156_205,TEM-1,beta-lactamase_156,P62593,0.266923,NO,205,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.922,-4.141,3.219,,,H,A,0.55,-0.46,0.678,,42.31,PHH,-1.57767,0.111618,0.00255802,0.266923 kka2_1:4_C209E,kka2_1:4_209,Kka2,kka2_1:4,P00552,0.267003,NO,209,C,E,CE,Special,negativeCharge,5.07,3.22,-1.85,170,121,147,26,108.5,138.4,29.9,-0.906,-4.141,3.235,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.168804,0.00260862,0.267003 Pab1_F129W,Pab1_129,Pab1,Pab1,P04147,0.267013,NO,129,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.269,-4.233,2.964,,0.219,E,B,0.03,-0.07,1.307,,73.83,HHH,-1.27533,0.175299,0.000625182,0.267013 E1_Ubiquitin_G76L,E1_Ubiquitin_76,Uba1,E1_Ubiquitin,P0CG63,0.26702,NO,76,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.999,-3.549,2.55,,0.23,,B,0.75,0.08,1.702,,83.73,OOO,-0.999,0.18783,0.00125575,0.26702 E1_Ubiquitin_R72H,E1_Ubiquitin_72,Uba1,E1_Ubiquitin,P0CG63,0.26702,NO,72,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.184,-4.047,2.863,,0.077,,B,0.16,-0.1,,,,HBH,-1.08733,0.18783,0.00129853,0.26702 beta-lactamase_2500_I277N,beta-lactamase_2500_277,TEM-1,beta-lactamase_2500,P62593,0.267055,NO,277,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.361275,0.0169305,0.267055 kka2_1:2_L19Q,kka2_1:2_19,Kka2,kka2_1:2,P00552,0.267063,NO,19,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.254,-4.298,3.044,,0.08,T,A,0.55,-0.26,17.165,17.165,65.53,BHH,-2.221,0.295029,0.00620703,0.267063 kka2_1:4_V214N,kka2_1:4_214,Kka2,kka2_1:4,P00552,0.267084,NO,214,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.261,-4.229,2.968,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.168804,0.00692782,0.267084 kka2_1:1_E169P,kka2_1:1_169,Kka2,kka2_1:1,P00552,0.267091,NO,169,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.996,-4.008,2.012,,0.422,H,A,1.04,0.3,7.546,7.546,65.53,HAH,-1.755,0.520039,0.00730086,0.267091 kka2_1:1_V113C,kka2_1:1_113,Kka2,kka2_1:1,P00552,0.267091,NO,113,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.233,-4.781,3.548,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.520039,0.00650191,0.267091 kka2_1:8_L102S,kka2_1:8_102,Kka2,kka2_1:8,P00552,0.267144,NO,102,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.804,-3.637,2.833,,,T,A,1.59,-1.17,0.97,,42.42,AHH,-1.398,0.100394,0.00201332,0.267144 kka2_1:8_L102S,kka2_1:8_102,Kka2,kka2_1:8,P00552,0.267144,NO,102,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.804,-3.637,2.833,,,T,A,1.59,-1.17,0.97,,42.42,AHH,-1.398,0.100394,0.00201332,0.267144 kka2_1:4_F263E,kka2_1:4_263,Kka2,kka2_1:4,P00552,0.267181,NO,263,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-0.911,-3.952,3.041,,0.006,G,A,0.58,-0.12,2.284,,45.83,AHH,-0.92,0.168804,0.0172454,0.267181 kka2_1:2_P45W,kka2_1:2_45,Kka2,kka2_1:2,P00552,0.267206,NO,45,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.774,-5.588,3.814,,0.669,,B,0.52,-0.76,4.882,,71.59,BOH,-2.152,0.295029,0.00590481,0.267206 beta-lactamase_156_S128E,beta-lactamase_156_128,TEM-1,beta-lactamase_156,P62593,0.267274,NO,128,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-0.84,-3.215,2.375,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.111618,0.00071483,0.267274 kka2_1:1_D261R,kka2_1:1_261,Kka2,kka2_1:1,P00552,0.267327,NO,261,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.708,-3.961,3.253,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.520039,0.0224846,0.267327 WW_domain_N191T,WW_domain_191,Yap65,WW_domain,P46937,0.267357,NO,191,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-1.519,-3.071,1.552,5.96016,,,,,,5.117,,66.07,HPB,-1.554,0.153962,0.00270999,0.267357 kka2_1:1_R211N,kka2_1:1_211,Kka2,kka2_1:1,P00552,0.267364,NO,211,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-0.899,-3.561,2.662,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.520039,0.00204888,0.267364 kka2_1:2_V36I,kka2_1:2_36,Kka2,kka2_1:2,P00552,0.267385,NO,36,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-0.898,-1.989,1.091,,0.292,E,B,1.48,0.21,1.064,,52.27,HHH,-1.484,0.295029,0.00245633,0.267385 kka2_1:8_C131S,kka2_1:8_131,Kka2,kka2_1:8,P00552,0.267451,NO,131,C,S,CS,Special,Polar,5.07,5.68,0.61,112,121,105,-16,108.5,89,-19.5,-0.831,-3.414,2.583,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.100394,0.00170814,0.267451 kka2_1:8_C131S,kka2_1:8_131,Kka2,kka2_1:8,P00552,0.267451,NO,131,C,S,CS,Special,Polar,5.07,5.68,0.61,112,121,105,-16,108.5,89,-19.5,-0.831,-3.414,2.583,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.100394,0.00170814,0.267451 beta-lactamase_2500_S104P,beta-lactamase_2500_104,TEM-1,beta-lactamase_2500,P62593,0.267548,NO,104,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.015,-3.751,2.736,,0.04,,b,0.27,0.57,1.133,,63.29,HPO,-1.05267,0.361275,0.00218083,0.267548 kka2_1:1_D101E,kka2_1:1_101,Kka2,kka2_1:1,P00552,0.267558,NO,101,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.028,-3.074,2.046,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.520039,0.00423361,0.267558 beta-lactamase_2500_W227I,beta-lactamase_2500_227,TEM-1,beta-lactamase_2500,P62593,0.267565,NO,227,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-0.982,-3.985,3.003,,0.272,,B,0.47,-0.29,1.37,,74.48,OHH,-1.595,0.361275,0.00226019,0.267565 kka2_1:8_D261F,kka2_1:8_261,Kka2,kka2_1:8,P00552,0.267603,NO,261,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.708,-4.32,3.612,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.100394,0.0224846,0.267603 kka2_1:8_D261F,kka2_1:8_261,Kka2,kka2_1:8,P00552,0.267603,NO,261,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.708,-4.32,3.612,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.100394,0.0224846,0.267603 kka2_1:8_S40P,kka2_1:8_40,Kka2,kka2_1:8,P00552,0.267603,NO,40,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.645,-3.224,0.579,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.100394,0.00693477,0.267603 kka2_1:8_S40P,kka2_1:8_40,Kka2,kka2_1:8,P00552,0.267603,NO,40,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.645,-3.224,0.579,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.100394,0.00693477,0.267603 beta-lactamase_625_A235W,beta-lactamase_625_235,TEM-1,beta-lactamase_625,P62593,0.267616,NO,235,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.266,-5.379,4.113,,0.32,E,B,0.46,-0.86,0.281,,50,OHO,-0.89,0.213352,0.00493474,0.267616 beta-lactamase_625_S233H,beta-lactamase_625_233,TEM-1,beta-lactamase_625,P62593,0.267636,NO,233,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.886,-4.67,2.784,,0.016,E,B,0.27,-1.01,1.773,,77.62,BPO,-1.17267,0.213352,0.00311415,0.267636 beta-lactamase_625_N134L,beta-lactamase_625_134,TEM-1,beta-lactamase_625,P62593,0.267642,NO,134,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-0.879,-3.581,2.702,,0.138,H,A,0.61,-0.6,3.776,,53.15,HPH,-1.02233,0.213352,0.000644786,0.267642 kka2_1:1_A150W,kka2_1:1_150,Kka2,kka2_1:1,P00552,0.267669,NO,150,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.949,-5.375,4.426,,0.544,T,A,0.46,1.34,2.333,,63.26,AHO,-1.272,0.520039,0.0045009,0.267669 beta-lactamase_2500_G281K,beta-lactamase_2500_281,TEM-1,beta-lactamase_2500,P62593,0.267712,NO,281,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.361275,0.0406482,0.267712 kka2_1:2_H106W,kka2_1:2_106,Kka2,kka2_1:2,P00552,0.267719,NO,106,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-3.13,-3.81,0.68,,1.065,.,a,0.17,-0.95,2.53,,71.59,PBH,-2.10433,0.295029,0.00730778,0.267719 kka2_1:4_K50N,kka2_1:4_50,Kka2,kka2_1:4,P00552,0.267839,NO,50,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-0.833,-3.499,2.666,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.168804,0.00138626,0.267839 beta-lactamase_39_L167Y,beta-lactamase_39_167,TEM-1,beta-lactamase_39,P62593,0.267852,NO,167,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.138,-4.067,2.929,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.0495842,0.00303566,0.267852 beta-lactamase_625_T27E,beta-lactamase_625_27,TEM-1,beta-lactamase_625,P62593,0.267876,NO,27,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.905,-2.714,0.809,,0.007,H,A,0.22,-0.37,3.72,,93.01,APH,-1.97933,0.213352,0.00306559,0.267876 beta-lactamase_S233L,beta-lactamase_233,TEM-1,beta-lactamase,P62593,0.267978,NO,233,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.886,-3.357,1.471,4.98121,0.016,E,B,0.48,-1.01,5.361,,77.62,BPO,-1.17267,0.221079,0.00311415,0.267978 kka2_1:2_R226Y,kka2_1:2_226,Kka2,kka2_1:2,P00552,0.268022,NO,226,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.392,-3.976,2.584,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.295029,0.0108032,0.268022 beta-lactamase_2500_I93R,beta-lactamase_2500_93,TEM-1,beta-lactamase_2500,P62593,0.268025,NO,93,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.401,-4.203,2.802,,0.128,E,B,0.48,0.44,19.374,19.374,67.83,BHB,-1.873,0.361275,0.00527066,0.268025 kka2_1:1_L232D,kka2_1:1_232,Kka2,kka2_1:1,P00552,0.268048,NO,232,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.514,-4.122,2.608,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.520039,0.00800103,0.268048 kka2_1:1_T73W,kka2_1:1_73,Kka2,kka2_1:1,P00552,0.268051,NO,73,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.51,-5.397,2.887,,0.309,H,A,0.22,0.35,4.126,,56.06,PPO,-2.02333,0.520039,0.00628605,0.268051 beta-lactamase_625_N130H,beta-lactamase_625_130,TEM-1,beta-lactamase_625,P62593,0.268075,NO,130,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-0.798,-4.005,3.207,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.213352,0.000683376,0.268075 beta-lactamase_625_D155I,beta-lactamase_625_155,TEM-1,beta-lactamase_625,P62593,0.268079,NO,155,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.889,-4.06,3.171,,0.049,,B,0.75,-0.9,4.922,,64.69,OAB,-1.62267,0.213352,0.00135315,0.268079 kka2_1:1_R217I,kka2_1:1_217,Kka2,kka2_1:1,P00552,0.268113,NO,217,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.158,-2.477,1.319,,0.252,T,A,1.2,-0.59,0.381,,52.27,ABH,-1.127,0.520039,0.0047191,0.268113 kka2_1:1_E142Y,kka2_1:1_142,Kka2,kka2_1:1,P00552,0.268137,NO,142,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.221,-4.391,2.17,,0.471,H,A,1.52,0.85,3.626,,65.53,HAB,-2.08033,0.520039,0.00748883,0.268137 kka2_1:2_L94A,kka2_1:2_94,Kka2,kka2_1:2,P00552,0.268141,NO,94,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.618,-3.195,1.577,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.295029,0.00520888,0.268141 kka2_1:1_G88Y,kka2_1:1_88,Kka2,kka2_1:1,P00552,0.268165,NO,88,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.689,-4.408,2.719,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.520039,0.00685559,0.268165 beta-lactamase_625_I277G,beta-lactamase_625_277,TEM-1,beta-lactamase_625,P62593,0.268178,NO,277,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.213352,0.0169305,0.268178 kka2_1:1_V36C,kka2_1:1_36,Kka2,kka2_1:1,P00552,0.268181,NO,36,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-0.898,-4.71,3.812,,0.292,E,B,0.44,0.21,0.278,,52.27,HHH,-1.484,0.520039,0.00245633,0.268181 kka2_1:2_G233Y,kka2_1:2_233,Kka2,kka2_1:2,P00552,0.268206,NO,233,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.748,-4.46,3.712,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.295029,0.00232366,0.268206 kka2_1:1_G233K,kka2_1:1_233,Kka2,kka2_1:1,P00552,0.268209,NO,233,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.748,-3.71,2.962,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.520039,0.00232366,0.268209 kka2_1:1_G233M,kka2_1:1_233,Kka2,kka2_1:1,P00552,0.268209,NO,233,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.748,-5.003,4.255,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.520039,0.00232366,0.268209 kka2_1:8_A222K,kka2_1:8_222,Kka2,kka2_1:8,P00552,0.268215,NO,222,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.725,-3.485,2.76,,,H,A,1.04,-1.21,,,,HHH,-1.10833,0.100394,0.00207657,0.268215 kka2_1:8_A222K,kka2_1:8_222,Kka2,kka2_1:8,P00552,0.268215,NO,222,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.725,-3.485,2.76,,,H,A,1.04,-1.21,,,,HHH,-1.10833,0.100394,0.00207657,0.268215 kka2_1:1_G30F,kka2_1:1_30,Kka2,kka2_1:1,P00552,0.268267,NO,30,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.596,-4.32,3.724,,0.54,S,g,0.29,3.76,,,,HOO,-1.51133,0.520039,0.00159208,0.268267 kka2_1:2_A117M,kka2_1:2_117,Kka2,kka2_1:2,P00552,0.268267,NO,117,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.828,-4.464,3.636,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.295029,0.00282984,0.268267 kka2_1:4_L39K,kka2_1:4_39,Kka2,kka2_1:4,P00552,0.268324,NO,39,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.223,-3.871,2.648,,,E,B,0.55,-1.21,1.998,,71.59,BHP,-1.69167,0.168804,0.00493618,0.268324 kka2_1:2_V185H,kka2_1:2_185,Kka2,kka2_1:2,P00552,0.268354,NO,185,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.045,-4.98,3.935,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.295029,0.00367031,0.268354 kka2_1:8_H162P,kka2_1:8_162,Kka2,kka2_1:8,P00552,0.268367,NO,162,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-2.319,-4.047,1.728,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.100394,0.00616145,0.268367 kka2_1:8_H162P,kka2_1:8_162,Kka2,kka2_1:8,P00552,0.268367,NO,162,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-2.319,-4.047,1.728,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.100394,0.00616145,0.268367 beta-lactamase_2500_G141W,beta-lactamase_2500_141,TEM-1,beta-lactamase_2500,P62593,0.268371,NO,141,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.828,-5.233,4.405,,0.575,T,l,0.29,-0.28,1.493,,64.69,HOO,-1.08933,0.361275,0.0012419,0.268371 kka2_1:4_F206P,kka2_1:4_206,Kka2,kka2_1:4,P00552,0.26841,NO,206,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.349,-4.311,2.962,,0.006,E,B,0.58,-1.21,1.342,,63.64,OHH,-1.04,0.168804,0.00936868,0.26841 kka2_1:2_D82Q,kka2_1:2_82,Kka2,kka2_1:2,P00552,0.268425,NO,82,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.946,-2.981,1.035,,0.341,E,b,0.75,0.52,11.923,11.923,63.64,HAH,-1.98,0.295029,0.00637516,0.268425 kka2_1:4_N200W,kka2_1:4_200,Kka2,kka2_1:4,P00552,0.268464,NO,200,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-2.446,-5.597,3.151,,0.756,T,L,0.61,-0.08,1.746,,64.39,APO,-2.08,0.168804,0.00838549,0.268464 hsp90_A587K,hsp90_587,hsp90,hsp90,P02829,0.26849,NO,587,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.456,-2.835,0,4.91216,0.049,H,A,0.55,-0.02,,,,PHP,-2.757,0.368192,0.000222939,0.26849 kka2_1:8_A191Q,kka2_1:8_191,Kka2,kka2_1:8,P00552,0.26852,NO,191,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.831,-3.962,3.131,,,,b,1.04,-0.94,1.306,,50,AHO,-0.868667,0.100394,0.00338807,0.26852 kka2_1:8_A191Q,kka2_1:8_191,Kka2,kka2_1:8,P00552,0.26852,NO,191,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.831,-3.962,3.131,,,,b,1.04,-0.94,1.306,,50,AHO,-0.868667,0.100394,0.00338807,0.26852 beta-lactamase_2500_W227N,beta-lactamase_2500_227,TEM-1,beta-lactamase_2500,P62593,0.268534,NO,227,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-0.982,-4.236,3.254,,0.272,,B,0.47,-0.29,1.37,,74.48,OHH,-1.595,0.361275,0.00226019,0.268534 beta-lactamase_156_D129G,beta-lactamase_156_129,TEM-1,beta-lactamase_156,P62593,0.268551,NO,129,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.816,-3.182,2.366,,,,B,0.75,-0.69,1.924,,34.97,PAP,-0.818,0.111618,0.00109178,0.268551 beta-lactamase_156_K32P,beta-lactamase_156_32,TEM-1,beta-lactamase_156,P62593,0.268551,NO,32,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.984,-3.947,1.963,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.111618,0.00401283,0.268551 beta-lactamase_625_N130V,beta-lactamase_625_130,TEM-1,beta-lactamase_625,P62593,0.268563,NO,130,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-0.798,-3.754,2.956,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.213352,0.000683376,0.268563 beta-lactamase_0_G76W,beta-lactamase_0_76,TEM-1,beta-lactamase_0,P62593,0.268573,NO,76,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.189,-5.284,4.095,,,H,A,0.29,-0.67,1.188,,67.83,OOH,-1.22267,0.0500837,0.00476637,0.268573 beta-lactamase_625_I261E,beta-lactamase_625_261,TEM-1,beta-lactamase_625,P62593,0.268593,NO,261,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.213352,0.0123091,0.268593 beta-lactamase_2500_N274M,beta-lactamase_2500_274,TEM-1,beta-lactamase_2500,P62593,0.26863,NO,274,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.361275,0.0110418,0.26863 beta-lactamase_625_L167E,beta-lactamase_625_167,TEM-1,beta-lactamase_625,P62593,0.268681,NO,167,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.138,-3.783,2.645,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.213352,0.00303566,0.268681 kka2_1:2_R258D,kka2_1:2_258,Kka2,kka2_1:2,P00552,0.268686,NO,258,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.626,-3.765,2.139,,0.316,H,A,1.2,-0.85,7.485,7.485,53.03,HBH,-1.25933,0.295029,0.00983174,0.268686 kka2_1:1_E86Y,kka2_1:1_86,Kka2,kka2_1:1,P00552,0.268774,NO,86,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.86,-2.948,1.088,,0.369,.,B,1.04,1.92,18.506,18.506,63.26,PAH,-1.98067,0.520039,0.00642858,0.268774 kka2_1:1_E59Y,kka2_1:1_59,Kka2,kka2_1:1,P00552,0.268813,NO,59,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-0.952,-4.251,3.299,,0.187,.,L,1.04,0.62,2.648,,50.38,PAH,-1.53,0.520039,0.00280355,0.268813 beta-lactamase_2500_R220Y,beta-lactamase_2500_220,TEM-1,beta-lactamase_2500,P62593,0.268818,NO,220,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-0.942,-4.188,3.246,,0.295,I,A,1.2,-0.76,2.175,,74.48,HBP,-1.33633,0.361275,0.00232421,0.268818 kka2_1:8_V80D,kka2_1:8_80,Kka2,kka2_1:8,P00552,0.268824,NO,80,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.144,-3.971,2.827,,0.358,E,B,1.48,-0.24,2.562,,63.64,HHH,-1.64633,0.100394,0.00488211,0.268824 kka2_1:8_V80D,kka2_1:8_80,Kka2,kka2_1:8,P00552,0.268824,NO,80,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.144,-3.971,2.827,,0.358,E,B,1.48,-0.24,2.562,,63.64,HHH,-1.64633,0.100394,0.00488211,0.268824 beta-lactamase_625_V260N,beta-lactamase_625_260,TEM-1,beta-lactamase_625,P62593,0.268842,NO,260,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.213352,0.00471757,0.268842 kka2_1:2_R226D,kka2_1:2_226,Kka2,kka2_1:2,P00552,0.26887,NO,226,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.392,-3.802,2.41,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.295029,0.0108032,0.26887 beta-lactamase_S104F,beta-lactamase_104,TEM-1,beta-lactamase,P62593,0.268879,NO,104,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.015,-4.127,3.112,4.92365,0.04,,b,0.82,0.57,4.02,,63.29,HPO,-1.05267,0.221079,0.00218083,0.268879 beta-lactamase_625_G243E,beta-lactamase_625_243,TEM-1,beta-lactamase_625,P62593,0.268888,NO,243,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.213352,0.00464034,0.268888 beta-lactamase_156_I125Y,beta-lactamase_156_125,TEM-1,beta-lactamase_156,P62593,0.268923,NO,125,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.441,-4.111,2.67,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.111618,0.00383964,0.268923 kka2_1:4_V186N,kka2_1:4_186,Kka2,kka2_1:4,P00552,0.268939,NO,186,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.011,-4.235,3.224,,,E,B,0.44,-0.61,0.679,,45.83,HHP,-1.10967,0.168804,0.00409703,0.268939 kka2_1:1_V84F,kka2_1:1_84,Kka2,kka2_1:1,P00552,0.268981,NO,84,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-2.279,-4.266,1.987,,0.258,E,B,0.44,1.03,3.484,,71.59,HHP,-2.337,0.520039,0.00724019,0.268981 kka2_1:1_V84P,kka2_1:1_84,Kka2,kka2_1:1,P00552,0.268981,NO,84,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-2.279,-4.01,1.731,,0.258,E,B,0.44,1.03,3.484,,71.59,HHP,-2.337,0.520039,0.00724019,0.268981 kka2_1:4_D208K,kka2_1:4_208,Kka2,kka2_1:4,P00552,0.268996,NO,208,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.708,-3.485,2.777,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.168804,0.00212588,0.268996 kka2_1:1_A222T,kka2_1:1_222,Kka2,kka2_1:1,P00552,0.269057,NO,222,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.725,-3.225,2.5,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.520039,0.00207657,0.269057 beta-lactamase_2500_L47N,beta-lactamase_2500_47,TEM-1,beta-lactamase_2500,P62593,0.269083,NO,47,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.876,-3.972,2.096,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.361275,0.00439844,0.269083 kka2_1:2_A144W,kka2_1:2_144,Kka2,kka2_1:2,P00552,0.269097,NO,144,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.859,-5.395,4.536,,,H,A,0.46,0.21,6.844,,52.65,BHB,-1.72933,0.295029,0.00231095,0.269097 kka2_1:8_I228C,kka2_1:8_228,Kka2,kka2_1:8,P00552,0.269129,NO,228,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.142,-4.738,3.596,,,H,A,1.52,-1.2,1.521,,71.59,AHH,-1.54633,0.100394,0.00458834,0.269129 kka2_1:8_I228C,kka2_1:8_228,Kka2,kka2_1:8,P00552,0.269129,NO,228,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.142,-4.738,3.596,,,H,A,1.52,-1.2,1.521,,71.59,AHH,-1.54633,0.100394,0.00458834,0.269129 beta-lactamase_2500_N168E,beta-lactamase_2500_168,TEM-1,beta-lactamase_2500,P62593,0.269157,NO,168,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-1.029,-3.29,2.261,,0.113,G,A,0.61,-0.4,2.9,,44.41,HPA,-1.13233,0.361275,0.00288667,0.269157 Pab1_G150V,Pab1_150,Pab1,Pab1,P04147,0.269204,NO,150,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.809,-3.571,2.762,,0.287,S,b,0.23,0.53,,,,HOA,-1.45233,0.175299,0.000323835,0.269204 beta-lactamase_625_L160Y,beta-lactamase_625_160,TEM-1,beta-lactamase_625,P62593,0.269252,NO,160,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.977,-3.98,3.003,,0.022,,B,0.55,-0.6,0.237,,44.41,BHA,-0.936,0.213352,0.00193775,0.269252 kka2_1:1_L93F,kka2_1:1_93,Kka2,kka2_1:1,P00552,0.269318,NO,93,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.815,-3.719,2.904,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.520039,0.00131498,0.269318 kka2_1:1_S105H,kka2_1:1_105,Kka2,kka2_1:1,P00552,0.269358,NO,105,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.945,-4.83,2.885,,0.056,S,B,0.27,-1.04,3.442,,65.53,PPB,-2.17033,0.520039,0.00847233,0.269358 kka2_1:1_L170A,kka2_1:1_170,Kka2,kka2_1:1,P00552,0.269392,NO,170,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.28,-2.219,0.939,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.520039,0.00730791,0.269392 kka2_1:1_P109F,kka2_1:1_109,Kka2,kka2_1:1,P00552,0.269408,NO,109,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.412,-4.386,2.974,,0.376,H,A,0.52,-1.25,18.506,18.506,65.53,HOH,-1.84567,0.520039,0.0070929,0.269408 beta-lactamase_2500_A124D,beta-lactamase_2500_124,TEM-1,beta-lactamase_2500,P62593,0.269409,NO,124,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.181,-3.709,2.528,,,H,A,0.46,-0.9,0.314,,64.34,HHH,-1.152,0.361275,0.00481399,0.269409 beta-lactamase_156_D129Y,beta-lactamase_156_129,TEM-1,beta-lactamase_156,P62593,0.269435,NO,129,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.816,-4.385,3.569,,,,B,0.75,-0.69,1.924,,34.97,PAP,-0.818,0.111618,0.00109178,0.269435 kka2_1:2_L232H,kka2_1:2_232,Kka2,kka2_1:2,P00552,0.269464,NO,232,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.514,-3.411,1.897,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.295029,0.00800103,0.269464 kka2_1:2_N195M,kka2_1:2_195,Kka2,kka2_1:2,P00552,0.269465,NO,195,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-0.836,-4.777,3.941,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.295029,0.00276134,0.269465 hsp90_M589P,hsp90_589,hsp90,hsp90,P02829,0.26948,NO,589,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-3.858,-3.033,0,4.72723,0.032,H,A,0.84,0.31,,,,PHA,-3.24233,0.368192,0.000222939,0.26948 kka2_1:1_G95I,kka2_1:1_95,Kka2,kka2_1:1,P00552,0.269507,NO,95,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-2.403,-3.966,1.563,,0.126,E,B,0.29,-0.74,7.822,,71.59,HOA,-2.198,0.520039,0.00743616,0.269507 kka2_1:4_R211N,kka2_1:4_211,Kka2,kka2_1:4,P00552,0.269527,NO,211,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-0.899,-3.561,2.662,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.168804,0.00204888,0.269527 beta-lactamase_2500_G249D,beta-lactamase_2500_249,TEM-1,beta-lactamase_2500,P62593,0.269585,NO,249,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.312,,,,0.256,S,B,0.23,0.04,30.841,30.841,72.73,HOO,-1.81367,0.361275,0.00220169,0.269585 kka2_1:8_L67D,kka2_1:8_67,Kka2,kka2_1:8,P00552,0.269585,NO,67,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.741,-4.172,3.431,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.100394,0.00102787,0.269585 kka2_1:8_L67D,kka2_1:8_67,Kka2,kka2_1:8,P00552,0.269585,NO,67,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.741,-4.172,3.431,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.100394,0.00102787,0.269585 beta-lactamase_625_L284R,beta-lactamase_625_284,TEM-1,beta-lactamase_625,P62593,0.269601,NO,284,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.213352,0.0686156,0.269601 beta-lactamase_156_T158Q,beta-lactamase_156_158,TEM-1,beta-lactamase_156,P62593,0.269613,NO,158,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.116,-3.908,2.792,,0.036,,B,0.22,-0.85,3.771,,69.58,HPB,-1.269,0.111618,0.00341825,0.269613 kka2_1:1_A110P,kka2_1:1_110,Kka2,kka2_1:1,P00552,0.269667,NO,110,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.064,-3.089,1.025,,0.175,H,A,1.04,-1.19,11.755,,71.59,OHA,-1.91867,0.520039,0.00759851,0.269667 kka2_1:1_D157T,kka2_1:1_157,Kka2,kka2_1:1,P00552,0.269672,NO,157,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.993,-3.488,2.495,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.520039,0.0042313,0.269672 kka2_1:1_R121P,kka2_1:1_121,Kka2,kka2_1:1,P00552,0.269718,NO,121,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.552,-4.003,2.451,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.520039,0.00523326,0.269718 kka2_1:8_G233P,kka2_1:8_233,Kka2,kka2_1:8,P00552,0.269737,NO,233,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.748,-3.907,3.159,,0.172,,b,0.75,-0.27,1.134,,49.24,HOO,-1.72067,0.100394,0.00232366,0.269737 kka2_1:8_G233P,kka2_1:8_233,Kka2,kka2_1:8,P00552,0.269737,NO,233,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.748,-3.907,3.159,,0.172,,b,0.75,-0.27,1.134,,49.24,HOO,-1.72067,0.100394,0.00232366,0.269737 beta-lactamase_156_I280K,beta-lactamase_156_280,TEM-1,beta-lactamase_156,P62593,0.269826,NO,280,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.111618,0.0530888,0.269826 kka2_1:1_R147K,kka2_1:1_147,Kka2,kka2_1:1,P00552,0.269863,NO,147,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.123,-3.064,1.941,,0.094,H,A,1.2,0.97,2.578,,64.02,PBH,-1.98267,0.520039,0.00549168,0.269863 beta-lactamase_2500_D212L,beta-lactamase_2500_212,TEM-1,beta-lactamase_2500,P62593,0.269874,NO,212,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.624,-3.598,1.974,,0.037,,b,0.75,-0.58,12.482,,74.48,HAB,-1.77667,0.361275,0.00644302,0.269874 kka2_1:2_A117D,kka2_1:2_117,Kka2,kka2_1:2,P00552,0.269914,NO,117,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.828,-3.786,2.958,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.295029,0.00282984,0.269914 kka2_1:1_Y257V,kka2_1:1_257,Kka2,kka2_1:1,P00552,0.269968,NO,257,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-1.064,-3.391,2.327,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.520039,0.0148191,0.269968 kka2_1:2_R140K,kka2_1:2_140,Kka2,kka2_1:2,P00552,0.269969,NO,140,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.351,-2.269,0.918,,0.12,H,A,1.2,0.2,0.352,,53.03,BBH,-1.885,0.295029,0.00430167,0.269969 beta-lactamase_625_E279P,beta-lactamase_625_279,TEM-1,beta-lactamase_625,P62593,0.269981,NO,279,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.213352,0.0192826,0.269981 kka2_1:2_R226E,kka2_1:2_226,Kka2,kka2_1:2,P00552,0.269983,NO,226,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.392,-3.484,2.092,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.295029,0.0108032,0.269983 beta-lactamase_625_G114I,beta-lactamase_625_114,TEM-1,beta-lactamase_625,P62593,0.270016,NO,114,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.094,-4.083,2.989,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.213352,0.00224919,0.270016 beta-lactamase_I244N,beta-lactamase_244,TEM-1,beta-lactamase,P62593,0.270026,NO,244,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.555,-4.114,2.559,5.35885,,E,B,0.01,-0.84,0.379,,77.62,HHH,-1.385,0.221079,0.00605379,0.270026 beta-lactamase_156_V82P,beta-lactamase_156_82,TEM-1,beta-lactamase_156,P62593,0.270063,NO,82,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.325,-4.008,2.683,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.111618,0.00397046,0.270063 kka2_1:1_W69N,kka2_1:1_69,Kka2,kka2_1:1,P00552,0.270063,NO,69,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-0.859,-4.344,3.485,,0.164,H,A,0.47,0.15,5.074,,38.64,PHH,-1.49967,0.520039,0.0012874,0.270063 kka2_1:1_F203K,kka2_1:1_203,Kka2,kka2_1:1,P00552,0.270134,NO,203,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-0.911,-3.934,3.023,,0.26,E,B,0.58,-0.92,7.323,,63.64,BHP,-1.34167,0.520039,0.00318738,0.270134 kka2_1:1_A215W,kka2_1:1_215,Kka2,kka2_1:1,P00552,0.270141,NO,215,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.968,-5.417,4.449,,0.039,E,B,0.46,-0.59,0.754,,50.38,HHA,-1.00467,0.520039,0.00529129,0.270141 beta-lactamase_2500_D129C,beta-lactamase_2500_129,TEM-1,beta-lactamase_2500,P62593,0.270151,NO,129,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.816,-5.136,4.32,,,,B,0.75,-0.69,1.29,,34.97,PAP,-0.818,0.361275,0.00109178,0.270151 kka2_1:1_L165N,kka2_1:1_165,Kka2,kka2_1:1,P00552,0.270159,NO,165,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-2.453,-3.932,1.479,,0.299,,B,1.59,1.12,2.47,,64.39,OHH,-1.90967,0.520039,0.00801161,0.270159 kka2_1:8_F263K,kka2_1:8_263,Kka2,kka2_1:8,P00552,0.270193,NO,263,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-0.911,-3.934,3.023,,0.006,G,A,1.62,-0.12,0.928,,45.83,AHH,-0.92,0.100394,0.0172454,0.270193 kka2_1:8_F263K,kka2_1:8_263,Kka2,kka2_1:8,P00552,0.270193,NO,263,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-0.911,-3.934,3.023,,0.006,G,A,1.62,-0.12,0.928,,45.83,AHH,-0.92,0.100394,0.0172454,0.270193 kka2_1:4_D127F,kka2_1:4_127,Kka2,kka2_1:4,P00552,0.270212,NO,127,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.364,-4.509,3.145,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.168804,0.00660501,0.270212 kka2_1:4_E262I,kka2_1:4_262,Kka2,kka2_1:4,P00552,0.270223,NO,262,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-0.829,-4.062,3.233,,0.059,G,A,1.04,-0.18,2.383,,42.42,AAH,-0.816,0.168804,0.0191586,0.270223 kka2_1:1_T73M,kka2_1:1_73,Kka2,kka2_1:1,P00552,0.270243,NO,73,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.51,-3.216,0.706,,0.309,H,A,0.22,0.35,4.126,,56.06,PPO,-2.02333,0.520039,0.00628605,0.270243 kka2_1:1_E161C,kka2_1:1_161,Kka2,kka2_1:1,P00552,0.270287,NO,161,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.581,-5.043,3.462,,0.829,G,A,1.04,2.24,1.612,,92.05,AAB,-1.861,0.520039,0.00760103,0.270287 kka2_1:1_L232Y,kka2_1:1_232,Kka2,kka2_1:1,P00552,0.2703,NO,232,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.514,-3.053,1.539,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.520039,0.00800103,0.2703 kka2_1:1_Y244K,kka2_1:1_244,Kka2,kka2_1:1,P00552,0.270302,NO,244,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-0.775,-3.71,2.935,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.520039,0.00453187,0.270302 kka2_1:1_F48K,kka2_1:1_48,Kka2,kka2_1:1,P00552,0.270324,NO,48,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.453,-3.972,2.519,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.520039,0.00475422,0.270324 kka2_1:4_L170W,kka2_1:4_170,Kka2,kka2_1:4,P00552,0.270324,NO,170,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.28,-5.33,4.05,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.168804,0.00730791,0.270324 kka2_1:8_I207W,kka2_1:8_207,Kka2,kka2_1:8,P00552,0.270344,NO,207,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.175,-5.409,4.234,,0.293,,B,1.52,-1.12,1.306,,56.06,HHA,-1.07733,0.100394,0.00611824,0.270344 kka2_1:8_I207W,kka2_1:8_207,Kka2,kka2_1:8,P00552,0.270344,NO,207,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.175,-5.409,4.234,,0.293,,B,1.52,-1.12,1.306,,56.06,HHA,-1.07733,0.100394,0.00611824,0.270344 beta-lactamase_39_A133Q,beta-lactamase_39_133,TEM-1,beta-lactamase_39,P62593,0.270398,NO,133,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.186,-4.056,2.87,,,H,A,0.46,-0.86,0.373,,67.83,HHP,-0.988333,0.0495842,0.00468022,0.270398 beta-lactamase_2500_S104K,beta-lactamase_2500_104,TEM-1,beta-lactamase_2500,P62593,0.270473,NO,104,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.015,-3.372,2.357,,0.04,,b,0.27,0.57,1.133,,63.29,HPO,-1.05267,0.361275,0.00218083,0.270473 kka2_1:2_N195E,kka2_1:2_195,Kka2,kka2_1:2,P00552,0.270489,NO,195,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-0.836,-3.211,2.375,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.295029,0.00276134,0.270489 kka2_1:8_A191K,kka2_1:8_191,Kka2,kka2_1:8,P00552,0.270496,NO,191,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.831,-3.519,2.688,,,,b,1.04,-0.94,1.306,,50,AHO,-0.868667,0.100394,0.00338807,0.270496 kka2_1:8_A191K,kka2_1:8_191,Kka2,kka2_1:8,P00552,0.270496,NO,191,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.831,-3.519,2.688,,,,b,1.04,-0.94,1.306,,50,AHO,-0.868667,0.100394,0.00338807,0.270496 kka2_1:1_A129W,kka2_1:1_129,Kka2,kka2_1:1,P00552,0.270518,NO,129,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.656,-5.587,3.931,,0.845,G,A,0.46,0.72,19.686,19.686,92.05,OHP,-1.99,0.520039,0.00726862,0.270518 beta-lactamase_156_E164K,beta-lactamase_156_164,TEM-1,beta-lactamase_156,P62593,0.270521,NO,164,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-0.948,-2.425,1.477,,0.011,T,B,1.04,-0.4,3.445,,64.69,HAO,-1.388,0.111618,0.00137286,0.270521 kka2_1:2_V36S,kka2_1:2_36,Kka2,kka2_1:2,P00552,0.270528,NO,36,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-0.898,-3.684,2.786,,0.292,E,B,1.48,0.21,1.064,,52.27,HHH,-1.484,0.295029,0.00245633,0.270528 beta-lactamase_39_N130W,beta-lactamase_39_130,TEM-1,beta-lactamase_39,P62593,0.27054,NO,130,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-0.798,-5.547,4.749,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.0495842,0.000683376,0.27054 E1_Ubiquitin_I44Y,E1_Ubiquitin_44,Uba1,E1_Ubiquitin,P0CG63,0.270557,NO,44,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.432,-3.677,2.245,,,E,B,0.27,-1.17,4.57,,78.74,HHH,-1.25633,0.18783,0.00209731,0.270557 beta-lactamase_625_V260E,beta-lactamase_625_260,TEM-1,beta-lactamase_625,P62593,0.270576,NO,260,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.213352,0.00471757,0.270576 beta-lactamase_2500_P65N,beta-lactamase_2500_65,TEM-1,beta-lactamase_2500,P62593,0.270593,NO,65,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.894,-3.952,3.058,,0.098,E,B,0.52,-0.62,0.3,,40.56,HOH,-1.03233,0.361275,0.00152776,0.270593 kka2_1:1_P98F,kka2_1:1_98,Kka2,kka2_1:1,P00552,0.270595,NO,98,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.526,-4.51,2.984,,0.391,S,B,0.52,-0.65,1.521,,63.26,HOO,-1.19167,0.520039,0.00622754,0.270595 beta-lactamase_A133N,beta-lactamase_133,TEM-1,beta-lactamase,P62593,0.270611,NO,133,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.186,-3.758,2.572,4.86423,,H,A,0.55,-0.86,2.649,,67.83,HHP,-0.988333,0.221079,0.00468022,0.270611 kka2_1:1_R202A,kka2_1:1_202,Kka2,kka2_1:1,P00552,0.270783,NO,202,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.761,-2.662,0.901,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.520039,0.00696498,0.270783 beta-lactamase_2500_E35S,beta-lactamase_2500_35,TEM-1,beta-lactamase_2500,P62593,0.270793,NO,35,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-0.869,-3.186,2.317,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.361275,0.00174441,0.270793 kka2_1:4_G151I,kka2_1:4_151,Kka2,kka2_1:4,P00552,0.270818,NO,151,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.873,-4.249,3.376,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.168804,0.00339918,0.270818 beta-lactamase_2500_S104W,beta-lactamase_2500_104,TEM-1,beta-lactamase_2500,P62593,0.270892,NO,104,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.015,-5.359,4.344,,0.04,,b,0.27,0.57,1.133,,63.29,HPO,-1.05267,0.361275,0.00218083,0.270892 beta-lactamase_2500_R275P,beta-lactamase_2500_275,TEM-1,beta-lactamase_2500,P62593,0.270924,NO,275,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.361275,0.0141984,0.270924 kka2_1:2_L260E,kka2_1:2_260,Kka2,kka2_1:2,P00552,0.270987,NO,260,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.741,-3.918,3.177,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.295029,0.0233782,0.270987 kka2_1:4_R217M,kka2_1:4_217,Kka2,kka2_1:4,P00552,0.271015,NO,217,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.158,-4.484,3.326,,0.252,T,A,1.2,-0.59,2.074,,52.27,ABH,-1.127,0.168804,0.0047191,0.271015 kka2_1:2_L102E,kka2_1:2_102,Kka2,kka2_1:2,P00552,0.271074,NO,102,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.804,-3.916,3.112,,,T,A,1.59,-1.17,4.258,,42.42,AHH,-1.398,0.295029,0.00201332,0.271074 kka2_1:8_A144Q,kka2_1:8_144,Kka2,kka2_1:8,P00552,0.271102,NO,144,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.859,-4.01,3.151,,,H,A,1.04,0.21,1.118,,52.65,BHB,-1.72933,0.100394,0.00231095,0.271102 kka2_1:8_A144Q,kka2_1:8_144,Kka2,kka2_1:8,P00552,0.271102,NO,144,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.859,-4.01,3.151,,,H,A,1.04,0.21,1.118,,52.65,BHB,-1.72933,0.100394,0.00231095,0.271102 kka2_1:8_R66W,kka2_1:8_66,Kka2,kka2_1:8,P00552,0.271102,NO,66,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-0.922,-5.385,4.463,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.100394,0.00161025,0.271102 kka2_1:8_R66W,kka2_1:8_66,Kka2,kka2_1:8,P00552,0.271102,NO,66,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-0.922,-5.385,4.463,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.100394,0.00161025,0.271102 kka2_1:1_A71H,kka2_1:1_71,Kka2,kka2_1:1,P00552,0.271114,NO,71,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.824,-3.209,1.385,,0.553,H,A,0.46,0.08,9.788,,64.39,HHP,-1.74033,0.520039,0.00727707,0.271114 kka2_1:1_D227L,kka2_1:1_227,Kka2,kka2_1:1,P00552,0.271175,NO,227,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.758,-3.54,1.782,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.520039,0.00745029,0.271175 kka2_1:2_D157K,kka2_1:2_157,Kka2,kka2_1:2,P00552,0.271178,NO,157,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.993,-3.506,2.513,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.295029,0.0042313,0.271178 kka2_1:4_T51E,kka2_1:4_51,Kka2,kka2_1:4,P00552,0.271209,NO,51,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.199,-3.693,1.494,,0.05,E,B,0.82,-0.05,13.165,13.165,63.64,BPA,-1.76767,0.168804,0.00628861,0.271209 kka2_1:1_D261W,kka2_1:1_261,Kka2,kka2_1:1,P00552,0.271235,NO,261,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.708,-5.576,4.868,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.520039,0.0224846,0.271235 kka2_1:2_P194C,kka2_1:2_194,Kka2,kka2_1:2,P00552,0.271245,NO,194,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.846,-5.109,4.263,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.295029,0.00314194,0.271245 kka2_1:1_H162V,kka2_1:1_162,Kka2,kka2_1:1,P00552,0.27127,NO,162,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-2.319,-3.881,1.562,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.520039,0.00616145,0.27127 beta-lactamase_625_S104W,beta-lactamase_625_104,TEM-1,beta-lactamase_625,P62593,0.271275,NO,104,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.015,-5.359,4.344,,0.04,,b,0.27,0.57,1.76,,63.29,HPO,-1.05267,0.213352,0.00218083,0.271275 kka2_1:4_H135N,kka2_1:4_135,Kka2,kka2_1:4,P00552,0.271287,NO,135,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-1.331,-3.533,2.202,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.168804,0.00532566,0.271287 beta-lactamase_625_T264P,beta-lactamase_625_264,TEM-1,beta-lactamase_625,P62593,0.271288,NO,264,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.213352,0.0119399,0.271288 kka2_1:2_Y244K,kka2_1:2_244,Kka2,kka2_1:2,P00552,0.271291,NO,244,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-0.775,-3.71,2.935,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.295029,0.00453187,0.271291 beta-lactamase_39_G43D,beta-lactamase_39_43,TEM-1,beta-lactamase_39,P62593,0.271295,NO,43,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.62,-3.469,2.849,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.0495842,0.00120151,0.271295 beta-lactamase_625_D129N,beta-lactamase_625_129,TEM-1,beta-lactamase_625,P62593,0.271305,NO,129,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.816,-3.272,2.456,,,,B,0.75,-0.69,0.171,,34.97,PAP,-0.818,0.213352,0.00109178,0.271305 kka2_1:1_I115Y,kka2_1:1_115,Kka2,kka2_1:1,P00552,0.271309,NO,115,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.606,-4.097,2.491,,0.105,H,A,0.48,-1.18,0.878,,65.53,PHH,-2.205,0.520039,0.00836567,0.271309 kka2_1:2_D190T,kka2_1:2_190,Kka2,kka2_1:2,P00552,0.271309,NO,190,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.708,-3.45,2.742,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.295029,0.00247989,0.271309 beta-lactamase_156_N130P,beta-lactamase_156_130,TEM-1,beta-lactamase_156,P62593,0.271359,NO,130,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-0.798,-3.88,3.082,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.111618,0.000683376,0.271359 beta-lactamase_2500_L205A,beta-lactamase_2500_205,TEM-1,beta-lactamase_2500,P62593,0.2714,NO,205,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.922,-3.132,2.21,,,H,A,0.55,-0.46,0.831,,42.31,PHH,-1.57767,0.361275,0.00255802,0.2714 kka2_1:2_Y244A,kka2_1:2_244,Kka2,kka2_1:2,P00552,0.271423,NO,244,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-0.775,-3.331,2.556,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.295029,0.00453187,0.271423 kka2_1:2_R258E,kka2_1:2_258,Kka2,kka2_1:2,P00552,0.271441,NO,258,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.626,-2.838,1.212,,0.316,H,A,1.2,-0.85,7.485,7.485,53.03,HBH,-1.25933,0.295029,0.00983174,0.271441 kka2_1:1_V36F,kka2_1:1_36,Kka2,kka2_1:1,P00552,0.271504,NO,36,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-0.898,-3.87,2.972,,0.292,E,B,0.44,0.21,0.278,,52.27,HHH,-1.484,0.520039,0.00245633,0.271504 kka2_1:4_F206E,kka2_1:4_206,Kka2,kka2_1:4,P00552,0.271517,NO,206,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.349,-3.931,2.582,,0.006,E,B,0.58,-1.21,1.342,,63.64,OHH,-1.04,0.168804,0.00936868,0.271517 kka2_1:2_G205H,kka2_1:2_205,Kka2,kka2_1:2,P00552,0.271542,NO,205,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.596,-4.708,4.112,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.295029,0.00221855,0.271542 kka2_1:2_R140N,kka2_1:2_140,Kka2,kka2_1:2,P00552,0.271574,NO,140,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.351,-3.614,2.263,,0.12,H,A,1.2,0.2,0.352,,53.03,BBH,-1.885,0.295029,0.00430167,0.271574 kka2_1:4_L260T,kka2_1:4_260,Kka2,kka2_1:4,P00552,0.271648,NO,260,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.741,-3.45,2.709,,0.022,H,A,0.55,-0.52,,,,HHA,-0.845667,0.168804,0.0233782,0.271648 kka2_1:1_E231P,kka2_1:1_231,Kka2,kka2_1:1,P00552,0.271659,NO,231,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.002,-3.957,1.955,,0.503,H,A,1.04,-0.23,25.629,25.629,63.26,AAH,-2.06267,0.520039,0.00732383,0.271659 kka2_1:1_P194C,kka2_1:1_194,Kka2,kka2_1:1,P00552,0.271662,NO,194,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.846,-5.109,4.263,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.520039,0.00314194,0.271662 kka2_1:4_F263N,kka2_1:4_263,Kka2,kka2_1:4,P00552,0.271677,NO,263,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-0.911,-4.185,3.274,,0.006,G,A,0.58,-0.12,2.284,,45.83,AHH,-0.92,0.168804,0.0172454,0.271677 beta-lactamase_39_C75P,beta-lactamase_39_75,TEM-1,beta-lactamase_39,P62593,0.271725,NO,75,C,P,CP,Special,Special,5.07,6.3,1.23,169,121,115,-6,108.5,112.7,4.2,-1.245,-4.012,2.767,,,H,A,0.46,-0.87,2.369,,50,HOO,-1.24333,0.0495842,0.0034616,0.271725 kka2_1:2_P109C,kka2_1:2_109,Kka2,kka2_1:2,P00552,0.271738,NO,109,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.412,-5.056,3.644,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.295029,0.0070929,0.271738 PSD95pdz3_G330M,PSD95pdz3_330,PSD95pdz3,PSD95pdz3,P31016,0.271762,NO,330,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.008,-4.612,3.604,4.68351,,,,,31.405,,,,OOA,-1.14,0.0758425,0.000962386,0.271762 kka2_1:1_S40L,kka2_1:1_40,Kka2,kka2_1:1,P00552,0.271857,NO,40,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.645,-3.085,0.44,,0.32,E,B,0.27,-0.9,25.997,25.997,71.59,HPH,-1.91567,0.520039,0.00693477,0.271857 kka2_1:8_A237W,kka2_1:8_237,Kka2,kka2_1:8,P00552,0.271857,NO,237,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.12,-5.457,3.337,,0.068,H,A,0.46,-0.71,0.449,,92.05,HHA,-2.10433,0.100394,0.012257,0.271857 kka2_1:8_A237W,kka2_1:8_237,Kka2,kka2_1:8,P00552,0.271857,NO,237,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.12,-5.457,3.337,,0.068,H,A,0.46,-0.71,0.449,,92.05,HHA,-2.10433,0.100394,0.012257,0.271857 kka2_1:1_A229I,kka2_1:1_229,Kka2,kka2_1:1,P00552,0.271868,NO,229,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.739,-3.861,2.122,,0.32,H,A,0.46,-0.7,6.549,,63.64,HHA,-1.851,0.520039,0.00942138,0.271868 kka2_1:1_C209E,kka2_1:1_209,Kka2,kka2_1:1,P00552,0.271882,NO,209,C,E,CE,Special,negativeCharge,5.07,3.22,-1.85,170,121,147,26,108.5,138.4,29.9,-0.906,-4.141,3.235,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.520039,0.00260862,0.271882 beta-lactamase_2500_D161K,beta-lactamase_2500_161,TEM-1,beta-lactamase_2500,P62593,0.2719,NO,161,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.891,-3.426,2.535,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.361275,0.000897697,0.2719 kka2_1:8_R217T,kka2_1:8_217,Kka2,kka2_1:8,P00552,0.271941,NO,217,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.158,-3.559,2.401,,0.252,T,A,0.16,-0.59,1.151,,52.27,ABH,-1.127,0.100394,0.0047191,0.271941 kka2_1:8_R217T,kka2_1:8_217,Kka2,kka2_1:8,P00552,0.271941,NO,217,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.158,-3.559,2.401,,0.252,T,A,0.16,-0.59,1.151,,52.27,ABH,-1.127,0.100394,0.0047191,0.271941 kka2_1:1_L102C,kka2_1:1_102,Kka2,kka2_1:1,P00552,0.271948,NO,102,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.804,-4.689,3.885,,,T,A,0.55,-1.17,4.258,,42.42,AHH,-1.398,0.520039,0.00201332,0.271948 beta-lactamase_625_V117G,beta-lactamase_625_117,TEM-1,beta-lactamase_625,P62593,0.271996,NO,117,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.53,-3.828,2.298,,,H,A,0.44,-0.34,1.23,,65.03,PHB,-1.741,0.213352,0.00467906,0.271996 kka2_1:1_A144C,kka2_1:1_144,Kka2,kka2_1:1,P00552,0.272012,NO,144,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.859,-4.523,3.664,,,H,A,0.46,0.21,0.842,,52.65,BHB,-1.72933,0.520039,0.00231095,0.272012 kka2_1:4_E262F,kka2_1:4_262,Kka2,kka2_1:4,P00552,0.272021,NO,262,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-0.829,-4.344,3.515,,0.059,G,A,1.04,-0.18,2.383,,42.42,AAH,-0.816,0.168804,0.0191586,0.272021 kka2_1:4_F48C,kka2_1:4_48,Kka2,kka2_1:4,P00552,0.272081,NO,48,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.453,-4.951,3.498,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.168804,0.00475422,0.272081 kka2_1:1_Y257W,kka2_1:1_257,Kka2,kka2_1:1,P00552,0.272148,NO,257,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-1.064,-4.353,3.289,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.520039,0.0148191,0.272148 kka2_1:8_T187R,kka2_1:8_187,Kka2,kka2_1:8,P00552,0.272159,NO,187,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.273,-3.94,2.667,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.100394,0.00693073,0.272159 kka2_1:8_T187R,kka2_1:8_187,Kka2,kka2_1:8,P00552,0.272159,NO,187,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.273,-3.94,2.667,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.100394,0.00693073,0.272159 kka2_1:2_A64L,kka2_1:2_64,Kka2,kka2_1:2,P00552,0.27216,NO,64,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.496,-2.596,1.1,,0.039,H,A,0.46,-0.57,14.509,14.509,56.06,AHH,-1.334,0.295029,0.00705578,0.27216 kka2_1:1_V75S,kka2_1:1_75,Kka2,kka2_1:1,P00552,0.272169,NO,75,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-2.06,-3.699,1.639,,0.042,.,B,0.44,-0.2,2.815,,71.59,OHO,-1.563,0.520039,0.00693733,0.272169 beta-lactamase_2500_A235K,beta-lactamase_2500_235,TEM-1,beta-lactamase_2500,P62593,0.272188,NO,235,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.266,-3.575,2.309,,0.32,E,B,0.46,-0.86,0.891,,50,OHO,-0.89,0.361275,0.00493474,0.272188 beta-lactamase_2500_K232M,beta-lactamase_2500_232,TEM-1,beta-lactamase_2500,P62593,0.272197,NO,232,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.012,-4.522,3.51,,,E,B,2.34,-1.1,3.048,,65.03,ABP,-1.238,0.361275,0.00313441,0.272197 beta-lactamase_625_R242Y,beta-lactamase_625_242,TEM-1,beta-lactamase_625,P62593,0.272204,NO,242,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.213352,0.00452879,0.272204 beta-lactamase_156_L135D,beta-lactamase_156_135,TEM-1,beta-lactamase_156,P62593,0.272244,NO,135,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.002,-4.125,3.123,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.111618,0.00244423,0.272244 kka2_1:4_L170A,kka2_1:4_170,Kka2,kka2_1:4,P00552,0.27231,NO,170,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.28,-2.219,0.939,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.168804,0.00730791,0.27231 kka2_1:8_D227K,kka2_1:8_227,Kka2,kka2_1:8,P00552,0.27231,NO,227,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.758,-3.364,1.606,,0.128,H,A,0.75,-0.63,0.281,,56.06,BAH,-1.43067,0.100394,0.00745029,0.27231 kka2_1:8_D227K,kka2_1:8_227,Kka2,kka2_1:8,P00552,0.27231,NO,227,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.758,-3.364,1.606,,0.128,H,A,0.75,-0.63,0.281,,56.06,BAH,-1.43067,0.100394,0.00745029,0.27231 kka2_1:1_L94V,kka2_1:1_94,Kka2,kka2_1:1,P00552,0.272328,NO,94,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.618,-2.483,0.865,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.520039,0.00520888,0.272328 kka2_1:1_D134M,kka2_1:1_134,Kka2,kka2_1:1,P00552,0.272374,NO,134,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.969,-4.823,3.854,,0.421,B,B,0.75,0.31,2.329,,49.62,HAB,-1.057,0.520039,0.00270812,0.272374 kka2_1:1_P128F,kka2_1:1_128,Kka2,kka2_1:1,P00552,0.272407,NO,128,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.922,-4.049,2.127,,0.316,G,A,0.52,0.4,2.178,,56.06,AOH,-1.64733,0.520039,0.00774689,0.272407 kka2_1:4_P128E,kka2_1:4_128,Kka2,kka2_1:4,P00552,0.272415,NO,128,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.922,-3.892,1.97,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.168804,0.00774689,0.272415 kka2_1:4_L174K,kka2_1:4_174,Kka2,kka2_1:4,P00552,0.272426,NO,174,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.952,-3.744,2.792,,,H,A,0.55,-0.31,1.339,,51.89,BHB,-2.08533,0.168804,0.00438501,0.272426 kka2_1:1_L184N,kka2_1:1_184,Kka2,kka2_1:1,P00552,0.272485,NO,184,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.496,-4.154,2.658,,0.489,E,B,0.55,-0.06,19.127,19.127,63.26,AHH,-1.24833,0.520039,0.00518742,0.272485 kka2_1:4_V36F,kka2_1:4_36,Kka2,kka2_1:4,P00552,0.272494,NO,36,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-0.898,-3.87,2.972,,0.292,E,B,0.44,0.21,0.278,,52.27,HHH,-1.484,0.168804,0.00245633,0.272494 beta-lactamase_625_D129A,beta-lactamase_625_129,TEM-1,beta-lactamase_625,P62593,0.272505,NO,129,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.816,-3.3,2.484,,,,B,0.75,-0.69,0.171,,34.97,PAP,-0.818,0.213352,0.00109178,0.272505 Pab1_L133P,Pab1_133,Pab1,Pab1,P04147,0.27251,NO,133,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.039,-3.922,2.883,,0.015,,B,1.75,1.03,,,,PHB,-1.22,0.175299,0.000345939,0.27251 kka2_1:2_D157R,kka2_1:2_157,Kka2,kka2_1:2,P00552,0.2726,NO,157,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.993,-3.936,2.943,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.295029,0.0042313,0.2726 kka2_1:1_N200W,kka2_1:1_200,Kka2,kka2_1:1,P00552,0.27261,NO,200,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-2.446,-5.597,3.151,,0.756,T,L,0.61,-0.08,17.299,17.299,64.39,APO,-2.08,0.520039,0.00838549,0.27261 beta-lactamase_2500_G281D,beta-lactamase_2500_281,TEM-1,beta-lactamase_2500,P62593,0.272627,NO,281,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.361275,0.0406482,0.272627 kka2_1:2_R211E,kka2_1:2_211,Kka2,kka2_1:2,P00552,0.272642,NO,211,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-0.899,-3.317,2.418,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.295029,0.00204888,0.272642 kka2_1:2_R211N,kka2_1:2_211,Kka2,kka2_1:2,P00552,0.272668,NO,211,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-0.899,-3.561,2.662,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.295029,0.00204888,0.272668 kka2_1:2_G205M,kka2_1:2_205,Kka2,kka2_1:2,P00552,0.272694,NO,205,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.596,-4.958,4.362,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.295029,0.00221855,0.272694 kka2_1:4_G201P,kka2_1:4_201,Kka2,kka2_1:4,P00552,0.272759,NO,201,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.56,-3.175,1.615,,0.149,T,l,0.29,-0.57,0.284,,52.65,POB,-1.92233,0.168804,0.00820117,0.272759 kka2_1:1_V185H,kka2_1:1_185,Kka2,kka2_1:1,P00552,0.272793,NO,185,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.045,-4.98,3.935,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.520039,0.00367031,0.272793 beta-lactamase_2500_D174T,beta-lactamase_2500_174,TEM-1,beta-lactamase_2500,P62593,0.273112,NO,174,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.738,-3.421,2.683,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.361275,0.00125633,0.273112 kka2_1:2_F256M,kka2_1:2_256,Kka2,kka2_1:2,P00552,0.273143,NO,256,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.49,-4.553,3.063,,,H,A,0.58,-0.78,1.653,,53.03,HHH,-1.423,0.295029,0.0132841,0.273143 kka2_1:1_I254H,kka2_1:1_254,Kka2,kka2_1:1,P00552,0.273186,NO,254,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.933,-4.91,2.977,,0.135,H,A,1.52,-0.6,1.859,,71.59,BHH,-1.668,0.520039,0.0132375,0.273186 kka2_1:8_M197P,kka2_1:8_197,Kka2,kka2_1:8,P00552,0.273213,NO,197,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.707,-4.141,2.434,,0.121,E,B,1.59,-1.19,4.408,,65.53,HHH,-1.847,0.100394,0.00921295,0.273213 kka2_1:8_M197P,kka2_1:8_197,Kka2,kka2_1:8,P00552,0.273213,NO,197,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.707,-4.141,2.434,,0.121,E,B,1.59,-1.19,4.408,,65.53,HHH,-1.847,0.100394,0.00921295,0.273213 beta-lactamase_39_V42D,beta-lactamase_39_42,TEM-1,beta-lactamase_39,P62593,0.273215,NO,42,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.564,-4.059,2.495,,0.017,E,B,0.44,-0.51,1.86,,63.99,BHO,-1.042,0.0495842,0.00404515,0.273215 kka2_1:2_G99E,kka2_1:2_99,Kka2,kka2_1:2,P00552,0.273232,NO,99,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.596,-3.693,3.097,,0.368,S,g,0.29,-0.87,,,,OOP,-1.63067,0.295029,0.00186055,0.273232 kka2_1:1_Q219Y,kka2_1:1_219,Kka2,kka2_1:1,P00552,0.273239,NO,219,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-0.93,-4.01,3.08,,0.088,H,A,0.4,-0.85,1.917,,50,HPA,-1.05167,0.520039,0.00237913,0.273239 kka2_1:1_L103T,kka2_1:1_103,Kka2,kka2_1:1,P00552,0.273255,NO,103,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-2.362,-2.414,0.052,,0.394,T,A,0.55,-0.99,4.121,,63.64,HHP,-1.534,0.520039,0.00574792,0.273255 kka2_1:1_L92E,kka2_1:1_92,Kka2,kka2_1:1,P00552,0.273288,NO,92,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.893,-3.919,3.026,,0.007,E,B,0.55,-0.19,1.447,,63.26,HHH,-0.962,0.520039,0.00307177,0.273288 kka2_1:1_Y22N,kka2_1:1_22,Kka2,kka2_1:1,P00552,0.273312,NO,22,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-1.583,-3.898,2.315,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.520039,0.00598977,0.273312 kka2_1:1_E230Y,kka2_1:1_230,Kka2,kka2_1:1,P00552,0.273361,NO,230,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.672,-2.09,-0.582,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.520039,0.00920051,0.273361 kka2_1:1_L243K,kka2_1:1_243,Kka2,kka2_1:1,P00552,0.273383,NO,243,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-2.651,-3.021,0.37,,0.277,H,A,0.55,-0.67,4.334,,92.05,HHH,-2.03767,0.520039,0.00884927,0.273383 kka2_1:4_L170N,kka2_1:4_170,Kka2,kka2_1:4,P00552,0.273398,NO,170,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.28,-4.225,2.945,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.168804,0.00730791,0.273398 beta-lactamase_625_S68C,beta-lactamase_625_68,TEM-1,beta-lactamase_625,P62593,0.273488,NO,68,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-0.913,-4.705,3.792,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.213352,0.000800065,0.273488 kka2_1:4_D220C,kka2_1:4_220,Kka2,kka2_1:4,P00552,0.273528,NO,220,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.787,-5.083,4.296,,,H,A,0.75,-1.14,1.237,,46.59,PAH,-1.152,0.168804,0.00158066,0.273528 beta-lactamase_2500_V260K,beta-lactamase_2500_260,TEM-1,beta-lactamase_2500,P62593,0.273671,NO,260,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.361275,0.00471757,0.273671 beta-lactamase_39_A246E,beta-lactamase_39_246,TEM-1,beta-lactamase_39,P62593,0.273787,NO,246,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.121,-3.906,1.785,,0.01,E,B,0.46,-1.01,1.331,,73.78,HHH,-1.55633,0.0495842,0.00569458,0.273787 kka2_1:1_L126S,kka2_1:1_126,Kka2,kka2_1:1,P00552,0.273787,NO,126,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.246,-3.666,2.42,,0.285,S,B,0.55,0.12,0.302,,51.89,PHA,-1.744,0.520039,0.0066485,0.273787 kka2_1:2_W24P,kka2_1:2_24,Kka2,kka2_1:2,P00552,0.273791,NO,24,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-1.779,-4.359,2.58,,0.477,E,B,1.51,-0.21,2.666,,56.06,AHH,-2.24467,0.295029,0.00631564,0.273791 kka2_1:1_L7H,kka2_1:1_7,Kka2,kka2_1:1,P00552,0.273869,NO,7,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.926,-2.581,0.655,,,,,,,18.934,18.934,71.59,OHB,-2.12333,0.520039,0.00269456,0.273869 kka2_1:1_K112H,kka2_1:1_112,Kka2,kka2_1:1,P00552,0.273899,NO,112,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-2.491,-4.863,2.372,,0.076,H,A,2.34,-1.37,23.433,23.433,56.06,ABH,-2.00133,0.520039,0.00645389,0.273899 kka2_1:1_K112W,kka2_1:1_112,Kka2,kka2_1:1,P00552,0.273899,NO,112,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-2.491,-5.516,3.025,,0.076,H,A,2.34,-1.37,23.433,23.433,56.06,ABH,-2.00133,0.520039,0.00645389,0.273899 kka2_1:8_V186P,kka2_1:8_186,Kka2,kka2_1:8,P00552,0.273964,NO,186,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.011,-4.069,3.058,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.100394,0.00409703,0.273964 kka2_1:8_V186P,kka2_1:8_186,Kka2,kka2_1:8,P00552,0.273964,NO,186,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.011,-4.069,3.058,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.100394,0.00409703,0.273964 hsp90_S586K,hsp90_586,hsp90,hsp90,P02829,0.273992,NO,586,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.764,-2.835,0,4.65438,,,B,0.93,0.15,,,,HPH,-3.157,0.368192,0.000222939,0.273992 beta-lactamase_625_I244D,beta-lactamase_625_244,TEM-1,beta-lactamase_625,P62593,0.274009,NO,244,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.555,-3.943,2.388,,,E,B,0.48,-0.84,2.061,,77.62,OHH,-1.385,0.213352,0.00605379,0.274009 E1_Ubiquitin_G75D,E1_Ubiquitin_75,Uba1,E1_Ubiquitin,P0CG63,0.274094,NO,75,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.999,-3.389,2.39,,0.552,T,A,0.75,0.9,4.369,,83.73,BOO,-1.1,0.18783,0.00153276,0.274094 E1_Ubiquitin_G75Q,E1_Ubiquitin_75,Uba1,E1_Ubiquitin,P0CG63,0.274094,NO,75,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.999,-3.783,2.784,,0.552,T,A,0.75,0.9,4.369,,83.73,BOO,-1.1,0.18783,0.00153276,0.274094 Pab1_I152N,Pab1_152,Pab1,Pab1,P04147,0.274135,NO,152,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.345,-4.016,2.671,,0.165,E,B,1.23,-0.71,1.288,,71.4,AHH,-1.59433,0.175299,0.000740963,0.274135 kka2_1:2_L94F,kka2_1:2_94,Kka2,kka2_1:2,P00552,0.274153,NO,94,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.618,-3.805,2.187,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.295029,0.00520888,0.274153 hsp90_W585R,hsp90_585,hsp90,hsp90,P02829,0.274156,NO,585,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-4.251,-3.086,0,5.31455,0.508,,B,1.22,0.43,,,,OHP,-3.17533,0.368192,0.000222939,0.274156 beta-lactamase_625_L248P,beta-lactamase_625_248,TEM-1,beta-lactamase_625,P62593,0.274158,NO,248,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.213352,0.00428493,0.274158 kka2_1:1_P12M,kka2_1:1_12,Kka2,kka2_1:1,P00552,0.274165,NO,12,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.853,-4.703,3.85,,,.,B,0.52,1.25,0.261,,48.11,POH,-1.80767,0.520039,0.00500011,0.274165 Ubiquitin_E34F,Ubiquitin_34,Uba1,Ubiquitin,P0CG48,0.274194,NO,34,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.294,-4.324,3.03,5.02178,0.406,H,A,1.62,0.6,1.295,,35.62,BAO,-1.24933,0.205827,0.000686048,0.274194 Ubiquitin_G75R,Ubiquitin_75,Uba1,Ubiquitin,P0CG48,0.274194,NO,75,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.613,-3.077,1.464,5.44099,0.552,T,A,0.73,0.9,4.017,,34.31,BOO,-1.66767,0.205827,0.000712673,0.274194 Ubiquitin_G76P,Ubiquitin_76,Uba1,Ubiquitin,P0CG48,0.274194,NO,76,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.651,-3.028,1.377,5.7647,0.23,,B,0.12,0.08,9.665,9.665,34.31,OOO,-1.632,0.205827,0.000653872,0.274194 Ubiquitin_I3Q,Ubiquitin_3,Uba1,Ubiquitin,P0CG48,0.274194,NO,3,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.402,-4.23,2.828,4.80819,,E,B,,-0.78,,,,PHH,-1.54533,0.205827,0.000836911,0.274194 Ubiquitin_I44G,Ubiquitin_44,Uba1,Ubiquitin,P0CG48,0.274194,NO,44,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.566,-3.53,1.964,4.71256,,E,B,0.27,-1.17,5.26,,39.71,HHH,-1.38567,0.205827,0.000613305,0.274194 Ubiquitin_K11E,Ubiquitin_11,Uba1,Ubiquitin,P0CG48,0.274194,NO,11,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.354,-2.463,1.109,5.16813,0.401,,B,2.81,0.84,0.335,,25.84,OBP,-1.346,0.205827,0.000535553,0.274194 Ubiquitin_K48S,Ubiquitin_48,Uba1,Ubiquitin,P0CG48,0.274194,NO,48,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.436,-2.606,1.17,5.03072,0.132,E,B,2.92,-0.28,1.539,,53.87,OBP,-1.6,0.205827,0.000394633,0.274194 Ubiquitin_K6W,Ubiquitin_6,Uba1,Ubiquitin,P0CG48,0.274194,NO,6,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.093,-5.336,4.243,4.84211,0.35,E,B,1.82,-0.62,1.502,,71.82,HBP,-1.36133,0.205827,0.000784795,0.274194 Ubiquitin_T7F,Ubiquitin_7,Uba1,Ubiquitin,P0CG48,0.274194,NO,7,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.415,-4.043,2.628,4.954,0.094,E,B,0.43,-0.78,0.805,,21.31,BPH,-1.41033,0.205827,0.000647855,0.274194 kka2_1:2_A117G,kka2_1:2_117,Kka2,kka2_1:2,P00552,0.274196,NO,117,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.828,-3.044,2.216,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.295029,0.00282984,0.274196 beta-lactamase_39_T179H,beta-lactamase_39_179,TEM-1,beta-lactamase_39,P62593,0.274234,NO,179,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.085,-2.971,1.886,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.0495842,0.00226045,0.274234 beta-lactamase_625_G249E,beta-lactamase_625_249,TEM-1,beta-lactamase_625,P62593,0.274252,NO,249,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.213352,0.00220169,0.274252 kka2_1:2_I141Y,kka2_1:2_141,Kka2,kka2_1:2,P00552,0.274263,NO,141,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.495,-4.112,2.617,,0.068,H,A,0.48,-0.01,0.819,,92.05,BHA,-1.689,0.295029,0.00744745,0.274263 kka2_1:1_D183C,kka2_1:1_183,Kka2,kka2_1:1,P00552,0.274269,NO,183,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.204,-5.235,4.031,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.520039,0.00426304,0.274269 kka2_1:1_D180W,kka2_1:1_180,Kka2,kka2_1:1,P00552,0.274304,NO,180,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.416,-5.59,3.174,,1.03,S,a,0.75,1.5,1.534,,71.59,OAO,-2.02933,0.520039,0.00756412,0.274304 beta-lactamase_R162I,beta-lactamase_162,TEM-1,beta-lactamase,P62593,0.274308,NO,162,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.016,-3.867,2.851,5.34456,0.124,S,B,0.68,-0.37,31.656,31.656,64.69,ABH,-1.25,0.221079,0.000561334,0.274308 kka2_1:4_R226Y,kka2_1:4_226,Kka2,kka2_1:4,P00552,0.274309,NO,226,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.392,-3.976,2.584,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.168804,0.0108032,0.274309 gb1_G267M,gb1_267,gb1,gb1,P06654,0.274313,NO,267,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.676,-4.229,2.553,,,,,,,1.361,,12.72,AOA,-1.61833,0.177985,0.00264655,0.274313 gb1_K257M,gb1_257,gb1,gb1,P06654,0.274313,NO,257,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.775,-4.287,2.512,,,,,,,0.896,,37.28,HBP,-1.70367,0.177985,0.00640304,0.274313 kka2_1:1_M116Y,kka2_1:1_116,Kka2,kka2_1:1,P00552,0.274357,NO,116,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-2.482,-2.927,0.445,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.520039,0.00745147,0.274357 kka2_1:2_V80N,kka2_1:2_80,Kka2,kka2_1:2,P00552,0.274435,NO,80,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.144,-4.197,3.053,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.295029,0.00488211,0.274435 beta-lactamase_2500_A133P,beta-lactamase_2500_133,TEM-1,beta-lactamase_2500,P62593,0.274443,NO,133,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.186,-3.811,2.625,,,H,A,0.46,-0.86,2.649,,67.83,HHP,-0.988333,0.361275,0.00468022,0.274443 kka2_1:1_V186N,kka2_1:1_186,Kka2,kka2_1:1,P00552,0.274472,NO,186,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.011,-4.235,3.224,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.520039,0.00409703,0.274472 kka2_1:4_G210N,kka2_1:4_210,Kka2,kka2_1:4,P00552,0.274475,NO,210,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.095,-3.653,2.558,,0.103,T,A,0.29,-0.62,0.271,,50,OOB,-0.966667,0.168804,0.00598378,0.274475 beta-lactamase_39_A123P,beta-lactamase_39_123,TEM-1,beta-lactamase_39,P62593,0.27448,NO,123,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.834,-3.704,2.87,,0.039,H,A,0.46,-0.72,0.705,,41.26,PHH,-1.47367,0.0495842,0.0010157,0.27448 beta-lactamase_156_G234N,beta-lactamase_156_234,TEM-1,beta-lactamase_156,P62593,0.274529,NO,234,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.62,-3.448,2.828,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.111618,0.000889577,0.274529 kka2_1:4_R211V,kka2_1:4_211,Kka2,kka2_1:4,P00552,0.274543,NO,211,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-0.899,-3.805,2.906,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.168804,0.00204888,0.274543 kka2_1:1_L170T,kka2_1:1_170,Kka2,kka2_1:1,P00552,0.274561,NO,170,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.28,-3.474,2.194,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.520039,0.00730791,0.274561 kka2_1:1_D208L,kka2_1:1_208,Kka2,kka2_1:1,P00552,0.274594,NO,208,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.708,-3.836,3.128,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.520039,0.00212588,0.274594 beta-lactamase_2500_N168Y,beta-lactamase_2500_168,TEM-1,beta-lactamase_2500,P62593,0.274601,NO,168,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-1.029,-4.205,3.176,,0.113,G,A,0.61,-0.4,2.9,,44.41,HPA,-1.13233,0.361275,0.00288667,0.274601 beta-lactamase_625_T179V,beta-lactamase_625_179,TEM-1,beta-lactamase_625,P62593,0.274613,NO,179,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.085,-3.247,2.162,,,E,B,0.22,-1.38,0.367,,73.08,PPH,-1.557,0.213352,0.00226045,0.274613 kka2_1:4_V185M,kka2_1:4_185,Kka2,kka2_1:4,P00552,0.274623,NO,185,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.045,-3.067,2.022,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.168804,0.00367031,0.274623 kka2_1:4_Y22N,kka2_1:4_22,Kka2,kka2_1:4,P00552,0.27463,NO,22,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-1.583,-3.898,2.315,,0.122,.,B,0.21,-0.8,1.838,,65.53,OHA,-1.80333,0.168804,0.00598977,0.27463 kka2_1:4_K112Y,kka2_1:4_112,Kka2,kka2_1:4,P00552,0.274743,NO,112,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-2.491,-4.32,1.829,,0.076,H,A,2.34,-1.37,0.39,,56.06,ABH,-2.00133,0.168804,0.00645389,0.274743 beta-lactamase_625_P181Q,beta-lactamase_625_181,TEM-1,beta-lactamase_625,P62593,0.274764,NO,181,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.813,-3.925,3.112,,,H,A,0.52,-1.14,1.797,,61.54,HOH,-1.795,0.213352,0.000703122,0.274764 kka2_1:1_I196P,kka2_1:1_196,Kka2,kka2_1:1,P00552,0.274787,NO,196,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-2.115,-4.338,2.223,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.520039,0.0107273,0.274787 kka2_1:1_Q252L,kka2_1:1_252,Kka2,kka2_1:1,P00552,0.274794,NO,252,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.63,-3.66,1.03,,0.906,H,A,0.64,0.35,1.369,,92.05,PPB,-2.20733,0.520039,0.0121001,0.274794 kka2_1:1_S204V,kka2_1:1_204,Kka2,kka2_1:1,P00552,0.274843,NO,204,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.353,-3.451,2.098,,0.144,E,A,0.27,-1.2,3.022,,65.53,HPO,-0.953333,0.520039,0.00881794,0.274843 kka2_1:1_A191P,kka2_1:1_191,Kka2,kka2_1:1,P00552,0.274846,NO,191,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.831,-2.353,1.522,,,.,b,0.46,-0.94,0.53,,50,AHO,-0.868667,0.520039,0.00338807,0.274846 kka2_1:1_R66W,kka2_1:1_66,Kka2,kka2_1:1,P00552,0.274859,NO,66,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-0.922,-5.385,4.463,,0.103,H,A,1.2,-0.2,2.659,,46.21,HBH,-1.13567,0.520039,0.00161025,0.274859 beta-lactamase_2500_T178H,beta-lactamase_2500_178,TEM-1,beta-lactamase_2500,P62593,0.274869,NO,178,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-0.791,-4.68,3.889,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.361275,0.000684366,0.274869 kka2_1:1_G181H,kka2_1:1_181,Kka2,kka2_1:1,P00552,0.274872,NO,181,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-2.698,-2.933,0.235,,0.379,S,B,0.75,0.78,15.356,15.356,71.59,AOA,-2.21,0.520039,0.00728319,0.274872 kka2_1:4_L212E,kka2_1:4_212,Kka2,kka2_1:4,P00552,0.274891,NO,212,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.904,-3.881,2.977,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.168804,0.0031426,0.274891 kka2_1:1_R44S,kka2_1:1_44,Kka2,kka2_1:1,P00552,0.274921,NO,44,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.062,-2.625,0.563,,0.487,S,B,1.2,-0.35,2.717,,71.59,OBO,-1.80767,0.520039,0.00745043,0.274921 beta-lactamase_39_L248N,beta-lactamase_39_248,TEM-1,beta-lactamase_39,P62593,0.274937,NO,248,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.0495842,0.00428493,0.274937 kka2_1:1_Y22Q,kka2_1:1_22,Kka2,kka2_1:1,P00552,0.274961,NO,22,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-1.583,-4.105,2.522,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.520039,0.00598977,0.274961 beta-lactamase_625_S128N,beta-lactamase_625_128,TEM-1,beta-lactamase_625,P62593,0.274989,NO,128,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-0.84,-3.223,2.383,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.213352,0.00071483,0.274989 kka2_1:4_E63Y,kka2_1:4_63,Kka2,kka2_1:4,P00552,0.274989,NO,63,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-0.762,-4.191,3.429,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.168804,0.00118399,0.274989 kka2_1:4_L174Q,kka2_1:4_174,Kka2,kka2_1:4,P00552,0.275008,NO,174,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.952,-4.163,3.211,,,H,A,0.55,-0.31,1.339,,51.89,BHB,-2.08533,0.168804,0.00438501,0.275008 kka2_1:1_C192I,kka2_1:1_192,Kka2,kka2_1:1,P00552,0.275015,NO,192,C,I,CI,Special,Hydrophobic,5.07,6.02,0.95,198,121,131,10,108.5,166.7,58.2,-1.067,-3.687,2.62,,0.095,.,B,0.46,-0.75,2.749,,50,HOH,-0.960333,0.520039,0.00485428,0.275015 kka2_1:4_S40P,kka2_1:4_40,Kka2,kka2_1:4,P00552,0.275018,NO,40,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.645,-3.224,0.579,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.168804,0.00693477,0.275018 kka2_1:2_L259N,kka2_1:2_259,Kka2,kka2_1:2,P00552,0.275035,NO,259,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.088,-4.082,2.994,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.295029,0.0206964,0.275035 kka2_1:1_P76H,kka2_1:1_76,Kka2,kka2_1:1,P00552,0.275075,NO,76,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.449,-4.835,3.386,,0.331,.,B,0.52,-0.41,0.345,,63.64,HOO,-1.662,0.520039,0.00625685,0.275075 kka2_1:1_E96W,kka2_1:1_96,Kka2,kka2_1:1,P00552,0.275106,NO,96,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.573,-5.436,2.863,,0.476,,B,1.52,-0.65,1.254,,71.59,OAH,-2.143,0.520039,0.00369441,0.275106 kka2_1:1_D154Q,kka2_1:1_154,Kka2,kka2_1:1,P00552,0.275128,NO,154,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.876,-3.709,2.833,,0.457,.,b,0.75,1.48,0.658,,52.65,HAP,-1.52467,0.520039,0.00292633,0.275128 kka2_1:1_L57V,kka2_1:1_57,Kka2,kka2_1:1,P00552,0.275175,NO,57,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.898,-2.47,0.572,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.520039,0.00723769,0.275175 beta-lactamase_625_D155C,beta-lactamase_625_155,TEM-1,beta-lactamase_625,P62593,0.275179,NO,155,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.889,-5.157,4.268,,0.049,,B,0.75,-0.9,4.922,,64.69,OAB,-1.62267,0.213352,0.00135315,0.275179 beta-lactamase_625_I245K,beta-lactamase_625_245,TEM-1,beta-lactamase_625,P62593,0.275185,NO,245,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.213352,0.00391032,0.275185 kka2_1:2_F48I,kka2_1:2_48,Kka2,kka2_1:2,P00552,0.275207,NO,48,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.453,-2.391,0.938,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.295029,0.00475422,0.275207 kka2_1:2_V75N,kka2_1:2_75,Kka2,kka2_1:2,P00552,0.275207,NO,75,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-2.06,-4.176,2.116,,0.042,.,B,0.44,-0.2,2.815,,71.59,OHO,-1.563,0.295029,0.00693733,0.275207 kka2_1:4_M116H,kka2_1:4_116,Kka2,kka2_1:4,P00552,0.275224,NO,116,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-2.482,-4.918,2.436,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.168804,0.00745147,0.275224 kka2_1:2_R38T,kka2_1:2_38,Kka2,kka2_1:2,P00552,0.275228,NO,38,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.207,-3.514,2.307,,0.355,E,B,1.2,-1.13,6.872,6.872,52.27,HBH,-1.28567,0.295029,0.00372499,0.275228 beta-lactamase_156_A133D,beta-lactamase_156_133,TEM-1,beta-lactamase_156,P62593,0.275233,NO,133,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.186,-3.675,2.489,,,H,A,0.46,-0.86,0.805,,67.83,HHP,-0.988333,0.111618,0.00468022,0.275233 kka2_1:1_L19W,kka2_1:1_19,Kka2,kka2_1:1,P00552,0.275296,NO,19,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.254,-5.02,3.766,,0.08,T,A,0.55,-0.26,17.165,17.165,65.53,BHH,-2.221,0.520039,0.00620703,0.275296 kka2_1:8_I221K,kka2_1:8_221,Kka2,kka2_1:8,P00552,0.275311,NO,221,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.739,-3.896,2.157,,,H,A,1.52,-1.15,1.599,,71.59,AHH,-1.08367,0.100394,0.00945908,0.275311 kka2_1:8_I221K,kka2_1:8_221,Kka2,kka2_1:8,P00552,0.275311,NO,221,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.739,-3.896,2.157,,,H,A,1.52,-1.15,1.599,,71.59,AHH,-1.08367,0.100394,0.00945908,0.275311 kka2_1:1_V97H,kka2_1:1_97,Kka2,kka2_1:1,P00552,0.275364,NO,97,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.453,-5.043,3.59,,0.083,,B,1.48,-0.83,13.576,13.576,53.03,AHO,-1.85067,0.520039,0.00737869,0.275364 beta-lactamase_39_V42R,beta-lactamase_39_42,TEM-1,beta-lactamase_39,P62593,0.275424,NO,42,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.564,-4.138,2.574,,0.017,E,B,0.44,-0.51,1.86,,63.99,BHO,-1.042,0.0495842,0.00404515,0.275424 kka2_1:2_I207H,kka2_1:2_207,Kka2,kka2_1:2,P00552,0.275433,NO,207,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.175,-5.02,3.845,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.295029,0.00611824,0.275433 kka2_1:8_D190P,kka2_1:8_190,Kka2,kka2_1:8,P00552,0.27546,NO,190,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.708,-3.683,2.975,,0.213,S,b,0.29,-0.82,,,,OAH,-0.711667,0.100394,0.00247989,0.27546 kka2_1:8_D190P,kka2_1:8_190,Kka2,kka2_1:8,P00552,0.27546,NO,190,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.708,-3.683,2.975,,0.213,S,b,0.29,-0.82,,,,OAH,-0.711667,0.100394,0.00247989,0.27546 Pab1_N127H,Pab1_127,Pab1,Pab1,P04147,0.275499,NO,127,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-1.079,-3.822,2.743,,0.138,E,B,1.05,-0.51,,,,OPH,-1.13633,0.175299,0.000805159,0.275499 kka2_1:2_E111F,kka2_1:2_111,Kka2,kka2_1:2,P00552,0.275506,NO,111,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.28,-4.475,2.195,,0.155,H,A,1.52,-1.14,2.792,,65.53,HAB,-2.27833,0.295029,0.00746789,0.275506 beta-lactamase_39_G43I,beta-lactamase_39_43,TEM-1,beta-lactamase_39,P62593,0.275507,NO,43,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.62,-4.235,3.615,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.0495842,0.00120151,0.275507 kka2_1:4_D216R,kka2_1:4_216,Kka2,kka2_1:4,P00552,0.275525,NO,216,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.785,-3.929,3.144,,0.018,E,B,0.75,-0.51,0.112,,19.32,HAB,-0.970333,0.168804,0.00229969,0.275525 kka2_1:1_Q100M,kka2_1:1_100,Kka2,kka2_1:1,P00552,0.275543,NO,100,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.77,-3.639,0.869,,0.646,E,B,0.4,-0.79,15.116,15.116,71.59,OPA,-1.46467,0.520039,0.0066405,0.275543 beta-lactamase_2500_L219D,beta-lactamase_2500_219,TEM-1,beta-lactamase_2500,P62593,0.275545,NO,219,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.313,-4.126,2.813,,,I,A,0.55,-0.51,35.994,35.994,74.48,HHB,-1.21533,0.361275,0.00664345,0.275545 kka2_1:2_L92T,kka2_1:2_92,Kka2,kka2_1:2,P00552,0.275634,NO,92,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.893,-3.472,2.579,,0.007,E,B,1.59,-0.19,1.447,,63.26,HHH,-0.962,0.295029,0.00307177,0.275634 kka2_1:1_L158A,kka2_1:1_158,Kka2,kka2_1:1,P00552,0.275646,NO,158,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.947,-3.292,1.345,,0.095,.,B,0.55,0.77,7.588,,63.64,AHA,-1.25333,0.520039,0.00529068,0.275646 kka2_1:1_I115Q,kka2_1:1_115,Kka2,kka2_1:1,P00552,0.275743,NO,115,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.606,-4.312,2.706,,0.105,H,A,0.48,-1.18,0.878,,65.53,PHH,-2.205,0.520039,0.00836567,0.275743 kka2_1:1_I141S,kka2_1:1_141,Kka2,kka2_1:1,P00552,0.27587,NO,141,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.495,-3.763,2.268,,0.068,H,A,0.48,-0.01,7.546,7.546,92.05,BHA,-1.689,0.520039,0.00744745,0.27587 kka2_1:1_I141Y,kka2_1:1_141,Kka2,kka2_1:1,P00552,0.27587,NO,141,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.495,-4.112,2.617,,0.068,H,A,0.48,-0.01,7.546,7.546,92.05,BHA,-1.689,0.520039,0.00744745,0.27587 beta-lactamase_625_R275P,beta-lactamase_625_275,TEM-1,beta-lactamase_625,P62593,0.27588,NO,275,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.213352,0.0141984,0.27588 beta-lactamase_156_L73R,beta-lactamase_156_73,TEM-1,beta-lactamase_156,P62593,0.275935,NO,73,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.507,-4.144,2.637,,,H,A,0.55,-0.64,2.09,,67.83,HHH,-1.487,0.111618,0.00488983,0.275935 beta-lactamase_D83F,beta-lactamase_83,TEM-1,beta-lactamase,P62593,0.275947,NO,83,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.066,-4.344,3.278,5.40616,0.354,H,A,1.33,0.22,0.861,,48.95,HAH,-1.34733,0.221079,0.00205968,0.275947 beta-lactamase_625_A123K,beta-lactamase_625_123,TEM-1,beta-lactamase_625,P62593,0.275961,NO,123,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.834,-3.506,2.672,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.213352,0.0010157,0.275961 beta-lactamase_625_F70K,beta-lactamase_625_70,TEM-1,beta-lactamase_625,P62593,0.275989,NO,70,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.169,-3.812,2.643,,,H,A,0.58,-1.34,1.14,,63.99,PHB,-0.980667,0.213352,0.00193499,0.275989 kka2_1:4_A191N,kka2_1:4_191,Kka2,kka2_1:4,P00552,0.276058,NO,191,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.831,-3.96,3.129,,,.,b,0.46,-0.94,2.046,,50,AHO,-0.868667,0.168804,0.00338807,0.276058 kka2_1:1_A215Y,kka2_1:1_215,Kka2,kka2_1:1,P00552,0.276059,NO,215,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.968,-4.276,3.308,,0.039,E,B,0.46,-0.59,0.754,,50.38,HHA,-1.00467,0.520039,0.00529129,0.276059 kka2_1:1_L67D,kka2_1:1_67,Kka2,kka2_1:1,P00552,0.27608,NO,67,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.741,-4.172,3.431,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.520039,0.00102787,0.27608 beta-lactamase_L282W,beta-lactamase_282,TEM-1,beta-lactamase,P62593,0.276099,NO,282,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.586,-5.21,3.624,5.16743,0.007,H,A,1.07,0.34,31.31,31.31,63.99,PHH,-1.82367,0.221079,0.0449821,0.276099 beta-lactamase_2500_I93C,beta-lactamase_2500_93,TEM-1,beta-lactamase_2500,P62593,0.276203,NO,93,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.401,-4.797,3.396,,0.128,E,B,0.48,0.44,19.374,19.374,67.83,BHB,-1.873,0.361275,0.00527066,0.276203 kka2_1:1_F133Q,kka2_1:1_133,Kka2,kka2_1:1,P00552,0.276231,NO,133,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-0.871,-4.345,3.474,,0.178,.,B,0.58,0.43,1.999,,42.42,OHA,-0.871667,0.520039,0.00182168,0.276231 beta-lactamase_625_G281R,beta-lactamase_625_281,TEM-1,beta-lactamase_625,P62593,0.27627,NO,281,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.213352,0.0406482,0.27627 kka2_1:1_P98E,kka2_1:1_98,Kka2,kka2_1:1,P00552,0.276271,NO,98,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.526,-2.413,0.887,,0.391,S,B,0.52,-0.65,1.521,,63.26,HOO,-1.19167,0.520039,0.00622754,0.276271 kka2_1:2_G233D,kka2_1:2_233,Kka2,kka2_1:2,P00552,0.276279,NO,233,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.748,-2.136,1.388,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.295029,0.00232366,0.276279 kka2_1:2_L260G,kka2_1:2_260,Kka2,kka2_1:2,P00552,0.276316,NO,260,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.741,-3.836,3.095,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.295029,0.0233782,0.276316 kka2_1:4_R258V,kka2_1:4_258,Kka2,kka2_1:4,P00552,0.276328,NO,258,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.626,-3.61,1.984,,0.316,H,A,1.2,-0.85,2.655,,53.03,HBH,-1.25933,0.168804,0.00983174,0.276328 kka2_1:2_L174Q,kka2_1:2_174,Kka2,kka2_1:2,P00552,0.276337,NO,174,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.952,-4.163,3.211,,,H,A,1.59,-0.31,8.521,,51.89,BHB,-2.08533,0.295029,0.00438501,0.276337 kka2_1:4_L232H,kka2_1:4_232,Kka2,kka2_1:4,P00552,0.276337,NO,232,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.514,-3.411,1.897,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.168804,0.00800103,0.276337 kka2_1:1_R143I,kka2_1:1_143,Kka2,kka2_1:1,P00552,0.276436,NO,143,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.525,-2.77,0.245,,0.325,H,A,0.16,1.22,3.6,,65.53,ABH,-1.86833,0.520039,0.00662247,0.276436 hsp90_S586H,hsp90_586,hsp90,hsp90,P02829,0.276482,NO,586,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.764,-3.833,0,4.65438,,,B,0.93,0.15,,,,HPH,-3.157,0.368192,0.000222939,0.276482 kka2_1:4_D208Y,kka2_1:4_208,Kka2,kka2_1:4,P00552,0.276484,NO,208,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.708,-4.416,3.708,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.168804,0.00212588,0.276484 beta-lactamase_T178H,beta-lactamase_178,TEM-1,beta-lactamase,P62593,0.276487,NO,178,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-0.791,-4.68,3.889,5.06452,0.029,E,B,0.3,-1.07,,,,APP,-0.947667,0.221079,0.000684366,0.276487 beta-lactamase_156_G243V,beta-lactamase_156_243,TEM-1,beta-lactamase_156,P62593,0.276512,NO,243,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.532,,,,,E,B,0.77,-1.24,2.866,,50,BOH,-1.46867,0.111618,0.00464034,0.276512 kka2_1:1_R147F,kka2_1:1_147,Kka2,kka2_1:1,P00552,0.276527,NO,147,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.123,-4.324,3.201,,0.094,H,A,1.2,0.97,2.578,,64.02,PBH,-1.98267,0.520039,0.00549168,0.276527 kka2_1:2_D82V,kka2_1:2_82,Kka2,kka2_1:2,P00552,0.276639,NO,82,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.946,-3.073,1.127,,0.341,E,b,0.75,0.52,11.923,11.923,63.64,HAH,-1.98,0.295029,0.00637516,0.276639 kka2_1:4_W69M,kka2_1:4_69,Kka2,kka2_1:4,P00552,0.276645,NO,69,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-0.859,-4.531,3.672,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.168804,0.0012874,0.276645 kka2_1:8_L93H,kka2_1:8_93,Kka2,kka2_1:8,P00552,0.276652,NO,93,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.815,-4.864,4.049,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.100394,0.00131498,0.276652 kka2_1:8_L93H,kka2_1:8_93,Kka2,kka2_1:8,P00552,0.276652,NO,93,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.815,-4.864,4.049,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.100394,0.00131498,0.276652 beta-lactamase_I278W,beta-lactamase_278,TEM-1,beta-lactamase,P62593,0.276669,NO,278,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.348,-5.377,4.029,5.35127,0.015,H,A,0.77,-0.85,2.718,,63.29,AHO,-1.41833,0.221079,0.0310297,0.276669 kka2_1:4_G205H,kka2_1:4_205,Kka2,kka2_1:4,P00552,0.276798,NO,205,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.596,-4.708,4.112,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.168804,0.00221855,0.276798 kka2_1:1_S105F,kka2_1:1_105,Kka2,kka2_1:1,P00552,0.276841,NO,105,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.945,-4.371,2.426,,0.056,S,B,0.27,-1.04,3.442,,65.53,PPB,-2.17033,0.520039,0.00847233,0.276841 kka2_1:4_D208W,kka2_1:4_208,Kka2,kka2_1:4,P00552,0.276866,NO,208,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.708,-5.576,4.868,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.168804,0.00212588,0.276866 kka2_1:4_L107E,kka2_1:4_107,Kka2,kka2_1:4,P00552,0.27687,NO,107,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.238,-3.847,2.609,,0.197,.,B,0.55,-1.1,0.398,,71.59,BHH,-2.143,0.168804,0.00561937,0.27687 kka2_1:1_Q61G,kka2_1:1_61,Kka2,kka2_1:1,P00552,0.276889,NO,61,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.982,-2.486,-0.496,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.520039,0.00612092,0.276889 kka2_1:1_R239F,kka2_1:1_239,Kka2,kka2_1:1,P00552,0.276896,NO,239,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.949,-4.366,1.417,,0.15,H,A,1.2,-0.31,0.477,,71.59,ABH,-2.23,0.520039,0.00835326,0.276896 beta-lactamase_39_M66R,beta-lactamase_39_66,TEM-1,beta-lactamase_39,P62593,0.276925,NO,66,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.362,-3.923,2.561,,0.013,,A,0.55,-0.7,1.319,,73.08,OHH,-1.49567,0.0495842,0.00412876,0.276925 kka2_1:1_Q136W,kka2_1:1_136,Kka2,kka2_1:1,P00552,0.277037,NO,136,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-3.021,-5.446,2.425,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.520039,0.00624149,0.277037 beta-lactamase_2500_L223D,beta-lactamase_2500_223,TEM-1,beta-lactamase_2500,P62593,0.27708,NO,223,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.055,-4.067,3.012,,0.27,,B,0.55,0.09,1.334,,74.48,HHO,-1.35033,0.361275,0.00372793,0.27708 beta-lactamase_2500_R257C,beta-lactamase_2500_257,TEM-1,beta-lactamase_2500,P62593,0.277167,NO,257,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.361275,0.00756629,0.277167 beta-lactamase_W227I,beta-lactamase_227,TEM-1,beta-lactamase,P62593,0.277189,NO,227,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-0.982,-3.985,3.003,4.86393,0.272,,B,0.99,-0.29,1.37,,74.48,OHH,-1.595,0.221079,0.00226019,0.277189 kka2_1:2_K112T,kka2_1:2_112,Kka2,kka2_1:2,P00552,0.277214,NO,112,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-2.491,-2.629,0.138,,0.076,H,A,2.34,-1.37,23.433,23.433,56.06,ABH,-2.00133,0.295029,0.00645389,0.277214 kka2_1:1_A224L,kka2_1:1_224,Kka2,kka2_1:1,P00552,0.277288,NO,224,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.977,-3.204,2.227,,,H,A,0.46,-1.26,1.725,,63.64,HHP,-1.41033,0.520039,0.00352047,0.277288 beta-lactamase_2500_V259E,beta-lactamase_2500_259,TEM-1,beta-lactamase_2500,P62593,0.277337,NO,259,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.361275,0.0070773,0.277337 beta-lactamase_156_W288A,beta-lactamase_156_288,TEM-1,beta-lactamase_156,P62593,0.277339,NO,288,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,,,,,,,,,,,,,BHO,,0.111618,,0.277339 beta-lactamase_L167Y,beta-lactamase_167,TEM-1,beta-lactamase,P62593,0.277349,NO,167,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.138,-4.067,2.929,5.13111,0.015,G,A,0.08,-0.63,0.4,,64.69,AHP,-1.30767,0.221079,0.00303566,0.277349 kka2_1:1_L126F,kka2_1:1_126,Kka2,kka2_1:1,P00552,0.277385,NO,126,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.246,-3.893,2.647,,0.285,S,B,0.55,0.12,0.302,,51.89,PHA,-1.744,0.520039,0.0066485,0.277385 WW_domain_T197N,WW_domain_197,Yap65,WW_domain,P46937,0.277388,NO,197,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.575,-2.309,0.734,6.59907,,,,,,21.052,21.052,70.04,PPP,-1.60267,0.153962,0.00319242,0.277388 beta-lactamase_625_T178K,beta-lactamase_625_178,TEM-1,beta-lactamase_625,P62593,0.277508,NO,178,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-0.791,-3.457,2.666,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.213352,0.000684366,0.277508 kka2_1:1_L107C,kka2_1:1_107,Kka2,kka2_1:1,P00552,0.277533,NO,107,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.238,-4.827,3.589,,0.197,.,B,0.55,-1.1,3.542,,71.59,BHH,-2.143,0.520039,0.00561937,0.277533 kka2_1:4_T225E,kka2_1:4_225,Kka2,kka2_1:4,P00552,0.277563,NO,225,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.393,-3.79,1.397,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.168804,0.0113598,0.277563 kka2_1:2_L170N,kka2_1:2_170,Kka2,kka2_1:2,P00552,0.277592,NO,170,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.28,-4.225,2.945,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.295029,0.00730791,0.277592 kka2_1:2_E262M,kka2_1:2_262,Kka2,kka2_1:2,P00552,0.277618,NO,262,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-0.829,-4.701,3.872,,0.059,G,A,1.04,-0.18,2.383,,42.42,AAH,-0.816,0.295029,0.0191586,0.277618 beta-lactamase_2500_E56F,beta-lactamase_2500_56,TEM-1,beta-lactamase_2500,P62593,0.277624,NO,56,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.043,-4.191,2.148,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.361275,0.00238534,0.277624 E1_Ubiquitin_G76Y,E1_Ubiquitin_76,Uba1,E1_Ubiquitin,P0CG63,0.27763,NO,76,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.999,,,,0.23,,B,0.75,0.08,1.702,,83.73,OOO,-0.999,0.18783,0.00125575,0.27763 beta-lactamase_C75D,beta-lactamase_75,TEM-1,beta-lactamase,P62593,0.27765,NO,75,C,D,CD,Special,negativeCharge,5.07,5.0516,-0.0184,154,121,133,12,108.5,111.1,2.6,-1.245,-3.832,2.587,4.88171,,H,A,0.25,-0.87,0.876,,50,HOO,-1.24333,0.221079,0.0034616,0.27765 kka2_1:1_R211Q,kka2_1:1_211,Kka2,kka2_1:1,P00552,0.277768,NO,211,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-0.899,-3.552,2.653,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.520039,0.00204888,0.277768 kka2_1:1_D62M,kka2_1:1_62,Kka2,kka2_1:1,P00552,0.277769,NO,62,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.591,-4.884,3.293,,0.262,H,A,0.75,0.08,10.048,10.048,64.39,PAA,-1.77833,0.520039,0.00744243,0.277769 kka2_1:1_D23I,kka2_1:1_23,Kka2,kka2_1:1,P00552,0.277778,NO,23,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.459,-4.001,1.542,,0.695,E,B,0.75,-0.65,2.655,,65.53,HAH,-1.94033,0.520039,0.007195,0.277778 kka2_1:1_E182F,kka2_1:1_182,Kka2,kka2_1:1,P00552,0.277795,NO,182,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.516,-4.259,2.743,,0.326,,B,1.52,0.75,14.547,14.547,65.53,OAA,-1.806,0.520039,0.00641548,0.277795 kka2_1:1_R211V,kka2_1:1_211,Kka2,kka2_1:1,P00552,0.277816,NO,211,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-0.899,-3.805,2.906,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.520039,0.00204888,0.277816 kka2_1:2_R253E,kka2_1:2_253,Kka2,kka2_1:2,P00552,0.27783,NO,253,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.356,-3.329,1.973,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.295029,0.0144195,0.27783 beta-lactamase_2500_L150D,beta-lactamase_2500_150,TEM-1,beta-lactamase_2500,P62593,0.277833,NO,150,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.326,-4.043,2.717,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.361275,0.00463171,0.277833 kka2_1:8_G213F,kka2_1:8_213,Kka2,kka2_1:8,P00552,0.27784,NO,213,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.596,-4.32,3.724,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.100394,0.00187654,0.27784 kka2_1:8_G213F,kka2_1:8_213,Kka2,kka2_1:8,P00552,0.27784,NO,213,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.596,-4.32,3.724,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.100394,0.00187654,0.27784 kka2_1:1_L193G,kka2_1:1_193,Kka2,kka2_1:1,P00552,0.277841,NO,193,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.983,-3.8,2.817,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.520039,0.00480179,0.277841 kka2_1:1_S54Y,kka2_1:1_54,Kka2,kka2_1:1,P00552,0.277859,NO,54,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.471,-4.321,1.85,,0.408,S,b,0.27,1.01,6.085,,71.59,HPO,-2.259,0.520039,0.00782867,0.277859 beta-lactamase_A132T,beta-lactamase_132,TEM-1,beta-lactamase,P62593,0.277928,NO,132,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.9,-3.22,2.32,4.58504,,H,A,2.34,-0.93,2.217,,64.69,PHH,-1.138,0.221079,0.000962524,0.277928 kka2_1:2_V49N,kka2_1:2_49,Kka2,kka2_1:2,P00552,0.277929,NO,49,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.614,-4.184,2.57,,,E,B,0.44,-0.77,1.233,,64.39,HHB,-1.3,0.295029,0.00615685,0.277929 kka2_1:1_L19S,kka2_1:1_19,Kka2,kka2_1:1,P00552,0.277941,NO,19,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.254,-3.764,2.51,,0.08,T,A,0.55,-0.26,17.165,17.165,65.53,BHH,-2.221,0.520039,0.00620703,0.277941 beta-lactamase_2500_I277A,beta-lactamase_2500_277,TEM-1,beta-lactamase_2500,P62593,0.277948,NO,277,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.361275,0.0169305,0.277948 kka2_1:8_T187E,kka2_1:8_187,Kka2,kka2_1:8,P00552,0.277984,NO,187,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.273,-3.655,2.382,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.100394,0.00693073,0.277984 kka2_1:8_T187E,kka2_1:8_187,Kka2,kka2_1:8,P00552,0.277984,NO,187,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.273,-3.655,2.382,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.100394,0.00693073,0.277984 kka2_1:8_I196A,kka2_1:8_196,Kka2,kka2_1:8,P00552,0.277988,NO,196,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-2.115,-3.338,1.223,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.100394,0.0107273,0.277988 kka2_1:8_I196A,kka2_1:8_196,Kka2,kka2_1:8,P00552,0.277988,NO,196,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-2.115,-3.338,1.223,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.100394,0.0107273,0.277988 kka2_1:2_A150P,kka2_1:2_150,Kka2,kka2_1:2,P00552,0.277997,NO,150,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.949,-3.782,2.833,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.295029,0.0045009,0.277997 beta-lactamase_625_G249R,beta-lactamase_625_249,TEM-1,beta-lactamase_625,P62593,0.278005,NO,249,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.213352,0.00220169,0.278005 kka2_1:2_P12E,kka2_1:2_12,Kka2,kka2_1:2,P00552,0.278014,NO,12,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.853,-3.478,2.625,,,.,B,0.52,1.25,0.261,,48.11,POH,-1.80767,0.295029,0.00500011,0.278014 kka2_1:1_G210E,kka2_1:1_210,Kka2,kka2_1:1,P00552,0.278037,NO,210,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.095,-3.693,2.598,,0.103,T,A,0.29,-0.62,14.483,14.483,50,OOB,-0.966667,0.520039,0.00598378,0.278037 beta-lactamase_156_L248E,beta-lactamase_156_248,TEM-1,beta-lactamase_156,P62593,0.278077,NO,248,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.111618,0.00428493,0.278077 PSD95pdz3_H372S,PSD95pdz3_372,PSD95pdz3,PSD95pdz3,P31016,0.278181,NO,372,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-1.627,-3.067,1.44,5.5607,,,,,17.008,,,,PBA,-1.63033,0.0758425,0.00040301,0.278181 kka2_1:2_D183I,kka2_1:2_183,Kka2,kka2_1:2,P00552,0.278183,NO,183,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.204,-3.991,2.787,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.295029,0.00426304,0.278183 beta-lactamase_T131R,beta-lactamase_131,TEM-1,beta-lactamase,P62593,0.278187,NO,131,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.328,-2.888,1.56,5.0548,,H,A,0.53,-0.69,3.306,,67.48,PPH,-1.00867,0.221079,0.00345886,0.278187 beta-lactamase_T69E,beta-lactamase_69,TEM-1,beta-lactamase,P62593,0.278187,NO,69,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-0.973,-3.476,2.503,5.16042,,G,A,0.69,-1.24,0.505,,93.01,PPH,-1.01833,0.221079,0.00127498,0.278187 kka2_1:2_D216F,kka2_1:2_216,Kka2,kka2_1:2,P00552,0.278231,NO,216,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.785,-4.288,3.503,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.295029,0.00229969,0.278231 beta-lactamase_2500_L219E,beta-lactamase_2500_219,TEM-1,beta-lactamase_2500,P62593,0.278355,NO,219,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.313,-3.999,2.686,,,I,A,0.55,-0.51,35.994,35.994,74.48,HHB,-1.21533,0.361275,0.00664345,0.278355 beta-lactamase_39_A132M,beta-lactamase_39_132,TEM-1,beta-lactamase_39,P62593,0.278367,NO,132,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.9,-4.473,3.573,,,H,A,0.46,-0.93,8.408,,64.69,PHH,-1.138,0.0495842,0.000962524,0.278367 kka2_1:1_P128E,kka2_1:1_128,Kka2,kka2_1:1,P00552,0.27837,NO,128,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.922,-3.892,1.97,,0.316,G,A,0.52,0.4,2.178,,56.06,AOH,-1.64733,0.520039,0.00774689,0.27837 kka2_1:1_T51E,kka2_1:1_51,Kka2,kka2_1:1,P00552,0.27841,NO,51,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.199,-3.693,1.494,,0.05,E,B,0.22,-0.05,3.056,,63.64,BPA,-1.76767,0.520039,0.00628861,0.27841 beta-lactamase_2500_G142R,beta-lactamase_2500_142,TEM-1,beta-lactamase_2500,P62593,0.27844,NO,142,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.707,-3.93,3.223,,0.034,,p,0.29,-0.64,1.883,,64.69,OOO,-0.834,0.361275,0.00060149,0.27844 beta-lactamase_2500_I244E,beta-lactamase_2500_244,TEM-1,beta-lactamase_2500,P62593,0.278461,NO,244,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.555,-3.795,2.24,,,E,B,0.48,-0.84,1.683,,77.62,OHH,-1.385,0.361275,0.00605379,0.278461 kka2_1:4_F48H,kka2_1:4_48,Kka2,kka2_1:4,P00552,0.278558,NO,48,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.453,-4.549,3.096,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.168804,0.00475422,0.278558 beta-lactamase_625_L167H,beta-lactamase_625_167,TEM-1,beta-lactamase_625,P62593,0.278568,NO,167,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.138,-4.852,3.714,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.213352,0.00303566,0.278568 beta-lactamase_2500_V214D,beta-lactamase_2500_214,TEM-1,beta-lactamase_2500,P62593,0.278609,NO,214,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.299,-3.873,2.574,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.361275,0.00628442,0.278609 kka2_1:1_A191N,kka2_1:1_191,Kka2,kka2_1:1,P00552,0.278609,NO,191,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.831,-3.96,3.129,,,.,b,0.46,-0.94,0.53,,50,AHO,-0.868667,0.520039,0.00338807,0.278609 kka2_1:1_T225P,kka2_1:1_225,Kka2,kka2_1:1,P00552,0.27862,NO,225,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.393,-4.067,1.674,,0.036,H,A,0.22,-1.22,4.554,,63.64,HPB,-1.58733,0.520039,0.0113598,0.27862 kka2_1:2_A117K,kka2_1:2_117,Kka2,kka2_1:2,P00552,0.278695,NO,117,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.828,-3.549,2.721,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.295029,0.00282984,0.278695 kka2_1:4_I221E,kka2_1:4_221,Kka2,kka2_1:4,P00552,0.278715,NO,221,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.739,-4.003,2.264,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.168804,0.00945908,0.278715 kka2_1:4_I141H,kka2_1:4_141,Kka2,kka2_1:4,P00552,0.278722,NO,141,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.495,-5.058,3.563,,0.068,H,A,0.48,-0.01,2.144,,92.05,BHA,-1.689,0.168804,0.00744745,0.278722 kka2_1:8_G233M,kka2_1:8_233,Kka2,kka2_1:8,P00552,0.278728,NO,233,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.748,-5.003,4.255,,0.172,,b,0.75,-0.27,1.134,,49.24,HOO,-1.72067,0.100394,0.00232366,0.278728 kka2_1:8_G233M,kka2_1:8_233,Kka2,kka2_1:8,P00552,0.278728,NO,233,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.748,-5.003,4.255,,0.172,,b,0.75,-0.27,1.134,,49.24,HOO,-1.72067,0.100394,0.00232366,0.278728 beta-lactamase_625_S128H,beta-lactamase_625_128,TEM-1,beta-lactamase_625,P62593,0.278741,NO,128,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-0.84,-4.455,3.615,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.213352,0.00071483,0.278741 kka2_1:1_N195F,kka2_1:1_195,Kka2,kka2_1:1,P00552,0.278767,NO,195,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-0.836,-4.344,3.508,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.520039,0.00276134,0.278767 kka2_1:1_K138S,kka2_1:1_138,Kka2,kka2_1:1,P00552,0.278784,NO,138,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-2.5,-2.62,0.12,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.520039,0.00628542,0.278784 kka2_1:1_L126A,kka2_1:1_126,Kka2,kka2_1:1,P00552,0.278785,NO,126,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.246,-3.18,1.934,,0.285,S,B,0.55,0.12,0.302,,51.89,PHA,-1.744,0.520039,0.0066485,0.278785 kka2_1:2_L60G,kka2_1:2_60,Kka2,kka2_1:2,P00552,0.278794,NO,60,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.997,-3.865,2.868,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.295029,0.00262176,0.278794 beta-lactamase_2500_L120H,beta-lactamase_2500_120,TEM-1,beta-lactamase_2500,P62593,0.278828,NO,120,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.044,-3.066,2.022,,,H,A,0.55,-1.13,2.48,,64.69,AHO,-1.13633,0.361275,0.00143563,0.278828 kka2_1:1_I246H,kka2_1:1_246,Kka2,kka2_1:1,P00552,0.278853,NO,246,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-2.008,-5.017,3.009,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.520039,0.0139479,0.278853 kka2_1:8_L223W,kka2_1:8_223,Kka2,kka2_1:8,P00552,0.278876,NO,223,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.861,-5.208,4.347,,,H,A,1.59,-1.24,1.017,,50,HHH,-0.854333,0.100394,0.00253574,0.278876 kka2_1:8_L223W,kka2_1:8_223,Kka2,kka2_1:8,P00552,0.278876,NO,223,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.861,-5.208,4.347,,,H,A,1.59,-1.24,1.017,,50,HHH,-0.854333,0.100394,0.00253574,0.278876 kka2_1:1_V97C,kka2_1:1_97,Kka2,kka2_1:1,P00552,0.278929,NO,97,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.453,-4.797,3.344,,0.083,,B,1.48,-0.83,13.576,13.576,53.03,AHO,-1.85067,0.520039,0.00737869,0.278929 kka2_1:1_A108M,kka2_1:1_108,Kka2,kka2_1:1,P00552,0.27894,NO,108,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.061,-4.804,2.743,,0.243,.,B,0.46,-1.34,3.156,,71.59,HHO,-1.57033,0.520039,0.00751209,0.27894 beta-lactamase_625_Y44A,beta-lactamase_625_44,TEM-1,beta-lactamase_625,P62593,0.278969,NO,44,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-2.547,-2.301,-0.246,,,E,B,0.21,-0.45,2.371,,73.78,OHH,-1.86267,0.213352,0.00426364,0.278969 kka2_1:1_D208W,kka2_1:1_208,Kka2,kka2_1:1,P00552,0.279013,NO,208,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.708,-5.576,4.868,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.520039,0.00212588,0.279013 kka2_1:8_A215W,kka2_1:8_215,Kka2,kka2_1:8,P00552,0.279024,NO,215,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.968,-5.417,4.449,,0.039,E,B,1.04,-0.59,2.77,,50.38,HHA,-1.00467,0.100394,0.00529129,0.279024 kka2_1:8_A215W,kka2_1:8_215,Kka2,kka2_1:8,P00552,0.279024,NO,215,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.968,-5.417,4.449,,0.039,E,B,1.04,-0.59,2.77,,50.38,HHA,-1.00467,0.100394,0.00529129,0.279024 kka2_1:8_T187L,kka2_1:8_187,Kka2,kka2_1:8,P00552,0.279024,NO,187,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.273,-3.26,1.987,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.100394,0.00693073,0.279024 kka2_1:8_T187L,kka2_1:8_187,Kka2,kka2_1:8,P00552,0.279024,NO,187,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.273,-3.26,1.987,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.100394,0.00693073,0.279024 kka2_1:2_F263T,kka2_1:2_263,Kka2,kka2_1:2,P00552,0.279031,NO,263,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-0.911,-3.673,2.762,,0.006,G,A,1.62,-0.12,5.275,,45.83,AHH,-0.92,0.295029,0.0172454,0.279031 kka2_1:1_F171T,kka2_1:1_171,Kka2,kka2_1:1,P00552,0.27904,NO,171,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.326,-3.738,2.412,,0.154,H,A,1.62,-0.1,13.679,13.679,63.64,HHH,-1.45433,0.520039,0.00821426,0.27904 kka2_1:2_F171G,kka2_1:2_171,Kka2,kka2_1:2,P00552,0.279049,NO,171,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.326,-3.793,2.467,,0.154,H,A,0.58,-0.1,2.645,,63.64,HHH,-1.45433,0.295029,0.00821426,0.279049 kka2_1:4_A237P,kka2_1:4_237,Kka2,kka2_1:4,P00552,0.279116,NO,237,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.12,-4.041,1.921,,0.068,H,A,0.46,-0.71,2.444,,92.05,HHA,-2.10433,0.168804,0.012257,0.279116 beta-lactamase_2500_I245F,beta-lactamase_2500_245,TEM-1,beta-lactamase_2500,P62593,0.279136,NO,245,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.361275,0.00391032,0.279136 kka2_1:1_P194Y,kka2_1:1_194,Kka2,kka2_1:1,P00552,0.279158,NO,194,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.846,-4.438,3.592,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.520039,0.00314194,0.279158 beta-lactamase_2500_D231R,beta-lactamase_2500_231,TEM-1,beta-lactamase_2500,P62593,0.279168,NO,231,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.816,-3.896,3.08,,,E,B,0.75,-1.06,0.319,,65.38,HAB,-0.994,0.361275,0.00107395,0.279168 kka2_1:4_N195M,kka2_1:4_195,Kka2,kka2_1:4,P00552,0.27918,NO,195,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-0.836,-4.777,3.941,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.168804,0.00276134,0.27918 kka2_1:1_F206E,kka2_1:1_206,Kka2,kka2_1:1,P00552,0.279185,NO,206,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.349,-3.931,2.582,,0.006,E,B,0.58,-1.21,0.978,,63.64,OHH,-1.04,0.520039,0.00936868,0.279185 kka2_1:1_F206K,kka2_1:1_206,Kka2,kka2_1:1,P00552,0.279194,NO,206,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.349,-3.906,2.557,,0.006,E,B,0.58,-1.21,0.978,,63.64,OHH,-1.04,0.520039,0.00936868,0.279194 kka2_1:2_P132W,kka2_1:2_132,Kka2,kka2_1:2,P00552,0.279231,NO,132,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.775,-5.574,4.799,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.295029,0.0018489,0.279231 beta-lactamase_2500_P181I,beta-lactamase_2500_181,TEM-1,beta-lactamase_2500,P62593,0.279325,NO,181,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.813,-3.974,3.161,,,H,A,0.52,-1.14,1.946,,61.54,HOH,-1.795,0.361275,0.000703122,0.279325 beta-lactamase_156_W208K,beta-lactamase_156_208,TEM-1,beta-lactamase_156,P62593,0.279342,NO,208,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-0.818,-3.907,3.089,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.111618,0.00126609,0.279342 beta-lactamase_T178R,beta-lactamase_178,TEM-1,beta-lactamase,P62593,0.279375,NO,178,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-0.791,-3.708,2.917,5.06452,0.029,E,B,0.3,-1.07,,,,APP,-0.947667,0.221079,0.000684366,0.279375 kka2_1:2_G245P,kka2_1:2_245,Kka2,kka2_1:2,P00552,0.279394,NO,245,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.812,-3.931,3.119,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.295029,0.00683899,0.279394 kka2_1:4_C77P,kka2_1:4_77,Kka2,kka2_1:4,P00552,0.279394,NO,77,C,P,CP,Special,Special,5.07,6.3,1.23,169,121,115,-6,108.5,112.7,4.2,-1.477,-4.052,2.575,,0.229,B,b,0.46,-0.57,2.499,,63.26,OOH,-1.55667,0.168804,0.00441216,0.279394 E1_Ubiquitin_G75I,E1_Ubiquitin_75,Uba1,E1_Ubiquitin,P0CG63,0.279399,NO,75,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.999,-4.046,3.047,,0.552,T,A,0.75,0.9,4.369,,83.73,BOO,-1.1,0.18783,0.00153276,0.279399 E1_Ubiquitin_I44F,E1_Ubiquitin_44,Uba1,E1_Ubiquitin,P0CG63,0.279399,NO,44,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.432,-3.612,2.18,,,E,B,0.27,-1.17,4.57,,78.74,HHH,-1.25633,0.18783,0.00209731,0.279399 kka2_1:4_R258W,kka2_1:4_258,Kka2,kka2_1:4,P00552,0.279454,NO,258,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.626,-5.364,3.738,,0.316,H,A,1.2,-0.85,2.655,,53.03,HBH,-1.25933,0.168804,0.00983174,0.279454 beta-lactamase_156_D129V,beta-lactamase_156_129,TEM-1,beta-lactamase_156,P62593,0.279548,NO,129,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.816,-3.751,2.935,,,,B,0.75,-0.69,1.924,,34.97,PAP,-0.818,0.111618,0.00109178,0.279548 kka2_1:4_R226K,kka2_1:4_226,Kka2,kka2_1:4,P00552,0.279568,NO,226,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.392,-3.285,1.893,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.168804,0.0108032,0.279568 kka2_1:1_I196F,kka2_1:1_196,Kka2,kka2_1:1,P00552,0.279583,NO,196,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-2.115,-1.503,-0.612,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.520039,0.0107273,0.279583 kka2_1:2_G99L,kka2_1:2_99,Kka2,kka2_1:2,P00552,0.279633,NO,99,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.596,-3.836,3.24,,0.368,S,g,0.29,-0.87,,,,OOP,-1.63067,0.295029,0.00186055,0.279633 beta-lactamase_625_G240D,beta-lactamase_625_240,TEM-1,beta-lactamase_625,P62593,0.279667,NO,240,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.213352,0.00591201,0.279667 beta-lactamase_39_D177W,beta-lactamase_39_177,TEM-1,beta-lactamase_39,P62593,0.279677,NO,177,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.967,-5.545,4.578,,0.006,T,L,0.75,-1.02,3.536,,64.69,BAP,-0.873667,0.0495842,0.000864022,0.279677 kka2_1:4_A222R,kka2_1:4_222,Kka2,kka2_1:4,P00552,0.279718,NO,222,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.725,-3.736,3.011,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.168804,0.00207657,0.279718 beta-lactamase_2500_G234M,beta-lactamase_2500_234,TEM-1,beta-lactamase_2500,P62593,0.279757,NO,234,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.62,-4.93,4.31,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.361275,0.000889577,0.279757 kka2_1:8_I196P,kka2_1:8_196,Kka2,kka2_1:8,P00552,0.279761,NO,196,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-2.115,-4.338,2.223,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.100394,0.0107273,0.279761 kka2_1:8_I196P,kka2_1:8_196,Kka2,kka2_1:8,P00552,0.279761,NO,196,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-2.115,-4.338,2.223,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.100394,0.0107273,0.279761 Pab1_F129A,Pab1_129,Pab1,Pab1,P04147,0.279771,NO,129,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.269,-3.173,1.904,,0.219,E,B,0.03,-0.07,1.307,,73.83,HHH,-1.27533,0.175299,0.000625182,0.279771 beta-lactamase_625_L248R,beta-lactamase_625_248,TEM-1,beta-lactamase_625,P62593,0.279814,NO,248,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.213352,0.00428493,0.279814 kka2_1:2_F171K,kka2_1:2_171,Kka2,kka2_1:2,P00552,0.27985,NO,171,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.326,-3.945,2.619,,0.154,H,A,0.58,-0.1,2.645,,63.64,HHH,-1.45433,0.295029,0.00821426,0.27985 kka2_1:1_A56L,kka2_1:1_56,Kka2,kka2_1:1,P00552,0.279896,NO,56,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.083,-2.797,0.714,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.520039,0.00717715,0.279896 kka2_1:8_V36F,kka2_1:8_36,Kka2,kka2_1:8,P00552,0.279909,NO,36,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-0.898,-3.87,2.972,,0.292,E,B,1.48,0.21,0.938,,52.27,HHH,-1.484,0.100394,0.00245633,0.279909 kka2_1:8_V36F,kka2_1:8_36,Kka2,kka2_1:8,P00552,0.279909,NO,36,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-0.898,-3.87,2.972,,0.292,E,B,1.48,0.21,0.938,,52.27,HHH,-1.484,0.100394,0.00245633,0.279909 beta-lactamase_625_N274L,beta-lactamase_625_274,TEM-1,beta-lactamase_625,P62593,0.27991,NO,274,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.213352,0.0110418,0.27991 beta-lactamase_625_L192N,beta-lactamase_625_192,TEM-1,beta-lactamase_625,P62593,0.279931,NO,192,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.254,-4.206,2.952,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.213352,0.00558728,0.279931 beta-lactamase_2500_A230K,beta-lactamase_2500_230,TEM-1,beta-lactamase_2500,P62593,0.279972,NO,230,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.154,-3.583,2.429,,0.01,E,B,0.46,-1.17,1.171,,50,HHA,-1.079,0.361275,0.00516841,0.279972 kka2_1:1_A119M,kka2_1:1_119,Kka2,kka2_1:1,P00552,0.280021,NO,119,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.073,-4.566,3.493,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.520039,0.00441074,0.280021 beta-lactamase_D83W,beta-lactamase_83,TEM-1,beta-lactamase,P62593,0.280024,NO,83,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.066,-5.509,4.443,5.40616,0.354,H,A,1.33,0.22,0.861,,48.95,HAH,-1.34733,0.221079,0.00205968,0.280024 beta-lactamase_2500_R162P,beta-lactamase_2500_162,TEM-1,beta-lactamase_2500,P62593,0.280034,NO,162,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.016,-2.671,1.655,,0.124,S,B,1.2,-0.37,6.199,,64.69,ABH,-1.25,0.361275,0.000561334,0.280034 kka2_1:1_V153S,kka2_1:1_153,Kka2,kka2_1:1,P00552,0.280092,NO,153,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.092,-3.643,2.551,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.520039,0.00501119,0.280092 beta-lactamase_2500_R59M,beta-lactamase_2500_59,TEM-1,beta-lactamase_2500,P62593,0.280126,NO,59,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.345,-4.605,3.26,,0.329,S,L,1.2,-0.09,3.719,,73.08,HBO,-2.24267,0.361275,0.00318082,0.280126 kka2_1:1_A229N,kka2_1:1_229,Kka2,kka2_1:1,P00552,0.280147,NO,229,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.739,-3.848,2.109,,0.32,H,A,0.46,-0.7,6.549,,63.64,HHA,-1.851,0.520039,0.00942138,0.280147 kka2_1:1_C209M,kka2_1:1_209,Kka2,kka2_1:1,P00552,0.280229,NO,209,C,M,CM,Special,Hydrophobic,5.07,5.74,0.67,196,121,149,28,108.5,162.9,54.4,-0.906,-4.438,3.532,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.520039,0.00260862,0.280229 beta-lactamase_E35F,beta-lactamase_35,TEM-1,beta-lactamase,P62593,0.280281,NO,35,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-0.869,-4.318,3.449,5.10723,0.15,H,A,0.52,0.21,1.081,,46.85,HAA,-1.88667,0.221079,0.00174441,0.280281 beta-lactamase_2500_I140K,beta-lactamase_2500_140,TEM-1,beta-lactamase_2500,P62593,0.280335,NO,140,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.733,-3.879,2.146,,0.128,H,A,0.48,0.41,1.628,,73.08,PHO,-1.48733,0.361275,0.00597777,0.280335 kka2_1:8_F48R,kka2_1:8_48,Kka2,kka2_1:8,P00552,0.28035,NO,48,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.453,-4.265,2.812,,0.296,E,B,1.62,-0.99,14.194,14.194,55.3,HHH,-1.444,0.100394,0.00475422,0.28035 kka2_1:8_F48R,kka2_1:8_48,Kka2,kka2_1:8,P00552,0.28035,NO,48,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.453,-4.265,2.812,,0.296,E,B,1.62,-0.99,14.194,14.194,55.3,HHH,-1.444,0.100394,0.00475422,0.28035 kka2_1:1_V36Q,kka2_1:1_36,Kka2,kka2_1:1,P00552,0.280361,NO,36,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-0.898,-4.235,3.337,,0.292,E,B,0.44,0.21,0.278,,52.27,HHH,-1.484,0.520039,0.00245633,0.280361 kka2_1:1_P249K,kka2_1:1_249,Kka2,kka2_1:1,P00552,0.280375,NO,249,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.867,-3.802,1.935,,0.406,.,B,0.52,-0.01,8.037,8.037,92.05,HOA,-1.66867,0.520039,0.011045,0.280375 beta-lactamase_156_D155P,beta-lactamase_156_155,TEM-1,beta-lactamase_156,P62593,0.280388,NO,155,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.889,-3.725,2.836,,0.049,,B,0.75,-0.9,0.315,,64.69,OAB,-1.62267,0.111618,0.00135315,0.280388 beta-lactamase_156_E119P,beta-lactamase_156_119,TEM-1,beta-lactamase_156,P62593,0.280406,NO,119,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.412,-3.828,2.416,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.111618,0.00386966,0.280406 kka2_1:1_C192H,kka2_1:1_192,Kka2,kka2_1:1,P00552,0.280415,NO,192,C,H,CH,Special,PositiveCharge,5.07,7.59,2.52,174,121,155,34,108.5,153.2,44.7,-1.067,-4.779,3.712,,0.095,.,B,0.46,-0.75,2.749,,50,HOH,-0.960333,0.520039,0.00485428,0.280415 kka2_1:1_P167W,kka2_1:1_167,Kka2,kka2_1:1,P00552,0.280471,NO,167,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-2.403,-5.529,3.126,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.520039,0.00543203,0.280471 beta-lactamase_2500_L135Y,beta-lactamase_2500_135,TEM-1,beta-lactamase_2500,P62593,0.280499,NO,135,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.002,-3.991,2.989,,0.117,H,A,0.55,-0.58,0.795,,43.71,PHH,-1.03767,0.361275,0.00244423,0.280499 kka2_1:2_M116Y,kka2_1:2_116,Kka2,kka2_1:2,P00552,0.280529,NO,116,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-2.482,-2.927,0.445,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.295029,0.00745147,0.280529 kka2_1:1_D52F,kka2_1:1_52,Kka2,kka2_1:1,P00552,0.280556,NO,52,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.271,-4.344,2.073,,0.22,E,B,0.75,0.8,2.64,,71.59,PAH,-2.38367,0.520039,0.00175694,0.280556 kka2_1:1_S105M,kka2_1:1_105,Kka2,kka2_1:1,P00552,0.280559,NO,105,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.945,-4.741,2.796,,0.056,S,B,0.27,-1.04,3.442,,65.53,PPB,-2.17033,0.520039,0.00847233,0.280559 kka2_1:1_L259D,kka2_1:1_259,Kka2,kka2_1:1,P00552,0.280567,NO,259,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.088,-4.066,2.978,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.520039,0.0206964,0.280567 kka2_1:2_V97F,kka2_1:2_97,Kka2,kka2_1:2,P00552,0.280635,NO,97,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.453,-3.895,2.442,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.295029,0.00737869,0.280635 kka2_1:4_G99L,kka2_1:4_99,Kka2,kka2_1:4,P00552,0.280638,NO,99,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.596,-3.836,3.24,,0.368,S,g,0.29,-0.87,,,,OOP,-1.63067,0.168804,0.00186055,0.280638 beta-lactamase_2500_T187Y,beta-lactamase_2500_187,TEM-1,beta-lactamase_2500,P62593,0.280639,NO,187,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.401,-4.271,2.87,,0.007,H,A,0.22,-1.19,3.91,,67.48,PPH,-1.69633,0.361275,0.00491782,0.280639 beta-lactamase_39_A185W,beta-lactamase_39_185,TEM-1,beta-lactamase_39,P62593,0.280644,NO,185,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.406,-5.387,3.981,,,H,A,0.46,-1.02,2.68,,65.03,HHP,-1.84033,0.0495842,0.00467449,0.280644 kka2_1:2_G99K,kka2_1:2_99,Kka2,kka2_1:2,P00552,0.280652,NO,99,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.596,-3.71,3.114,,0.368,S,g,0.29,-0.87,,,,OOP,-1.63067,0.295029,0.00186055,0.280652 beta-lactamase_625_A247R,beta-lactamase_625_247,TEM-1,beta-lactamase_625,P62593,0.280668,NO,247,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.213352,0.00611275,0.280668 beta-lactamase_T107F,beta-lactamase_107,TEM-1,beta-lactamase,P62593,0.280725,NO,107,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.117,-4.119,3.002,5.23432,,G,A,2.12,-0.06,3.676,,67.83,HPA,-1.265,0.221079,0.00239347,0.280725 kka2_1:1_T51I,kka2_1:1_51,Kka2,kka2_1:1,P00552,0.280827,NO,51,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.199,-2.59,0.391,,0.05,E,B,0.22,-0.05,3.056,,63.64,BPA,-1.76767,0.520039,0.00628861,0.280827 kka2_1:4_A144N,kka2_1:4_144,Kka2,kka2_1:4,P00552,0.280857,NO,144,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.859,-4.009,3.15,,,H,A,0.46,0.21,6.844,,52.65,BHB,-1.72933,0.168804,0.00231095,0.280857 kka2_1:1_P249F,kka2_1:1_249,Kka2,kka2_1:1,P00552,0.280866,NO,249,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.867,-3.04,1.173,,0.406,.,B,0.52,-0.01,8.037,8.037,92.05,HOA,-1.66867,0.520039,0.011045,0.280866 hsp90_A587R,hsp90_587,hsp90,hsp90,P02829,0.280875,NO,587,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.456,-3.086,0,4.91216,0.049,H,A,0.55,-0.02,,,,PHP,-2.757,0.368192,0.000222939,0.280875 beta-lactamase_2500_G240V,beta-lactamase_2500_240,TEM-1,beta-lactamase_2500,P62593,0.280901,NO,240,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.361275,0.00591201,0.280901 beta-lactamase_156_I206P,beta-lactamase_156_206,TEM-1,beta-lactamase_156,P62593,0.280928,NO,206,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-2.429,-4.04,1.611,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.111618,0.00528934,0.280928 kka2_1:4_G245E,kka2_1:4_245,Kka2,kka2_1:4,P00552,0.280934,NO,245,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.812,-2.733,1.921,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.168804,0.00683899,0.280934 kka2_1:2_A71L,kka2_1:2_71,Kka2,kka2_1:2,P00552,0.280969,NO,71,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.824,-3.593,1.769,,0.553,H,A,0.46,0.08,9.788,,64.39,HHP,-1.74033,0.295029,0.00727707,0.280969 beta-lactamase_2500_W288I,beta-lactamase_2500_288,TEM-1,beta-lactamase_2500,P62593,0.280978,NO,288,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,,,,,,,,,,,,,BHO,,0.361275,,0.280978 kka2_1:2_L260T,kka2_1:2_260,Kka2,kka2_1:2,P00552,0.281006,NO,260,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.741,-3.45,2.709,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.295029,0.0233782,0.281006 kka2_1:4_R258P,kka2_1:4_258,Kka2,kka2_1:4,P00552,0.28105,NO,258,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.626,-4.055,2.429,,0.316,H,A,1.2,-0.85,2.655,,53.03,HBH,-1.25933,0.168804,0.00983174,0.28105 beta-lactamase_2500_S233K,beta-lactamase_2500_233,TEM-1,beta-lactamase_2500,P62593,0.281083,NO,233,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.886,-3.496,1.61,,0.016,E,B,0.27,-1.01,2.851,,77.62,BPO,-1.17267,0.361275,0.00311415,0.281083 kka2_1:1_D62I,kka2_1:1_62,Kka2,kka2_1:1,P00552,0.281116,NO,62,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.591,-4.096,2.505,,0.262,H,A,0.75,0.08,10.048,10.048,64.39,PAA,-1.77833,0.520039,0.00744243,0.281116 beta-lactamase_2500_G281N,beta-lactamase_2500_281,TEM-1,beta-lactamase_2500,P62593,0.28119,NO,281,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.361275,0.0406482,0.28119 beta-lactamase_G236V,beta-lactamase_236,TEM-1,beta-lactamase,P62593,0.281193,NO,236,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.784,-3.686,2.902,4.7915,0.241,,b,0.23,-0.59,1.883,,64.69,HOA,-1.36933,0.221079,0.00162372,0.281193 kka2_1:1_E231S,kka2_1:1_231,Kka2,kka2_1:1,P00552,0.281209,NO,231,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.002,-3.227,1.225,,0.503,H,A,1.04,-0.23,25.629,25.629,63.26,AAH,-2.06267,0.520039,0.00732383,0.281209 beta-lactamase_G248K,beta-lactamase_248,TEM-1,beta-lactamase,P62593,0.281258,NO,248,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.794,-3.638,1.844,4.69798,,E,b,0.23,-0.43,1.782,,61.19,HOO,-1.52867,0.221079,0.00428493,0.281258 beta-lactamase_L167R,beta-lactamase_167,TEM-1,beta-lactamase,P62593,0.281275,NO,167,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.138,-2.876,1.738,5.13111,0.015,G,A,0.08,-0.63,0.4,,64.69,AHP,-1.30767,0.221079,0.00303566,0.281275 beta-lactamase_2500_P181M,beta-lactamase_2500_181,TEM-1,beta-lactamase_2500,P62593,0.281296,NO,181,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.813,-4.702,3.889,,,H,A,0.52,-1.14,1.946,,61.54,HOH,-1.795,0.361275,0.000703122,0.281296 kka2_1:8_A78L,kka2_1:8_78,Kka2,kka2_1:8,P00552,0.281378,NO,78,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.744,-3.506,1.762,,0.078,,B,1.04,-0.53,1.251,,56.06,OHH,-1.863,0.100394,0.00457299,0.281378 kka2_1:8_A78L,kka2_1:8_78,Kka2,kka2_1:8,P00552,0.281378,NO,78,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.744,-3.506,1.762,,0.078,,B,1.04,-0.53,1.251,,56.06,OHH,-1.863,0.100394,0.00457299,0.281378 beta-lactamase_2500_G240C,beta-lactamase_2500_240,TEM-1,beta-lactamase_2500,P62593,0.281379,NO,240,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.361275,0.00591201,0.281379 beta-lactamase_2500_I261W,beta-lactamase_2500_261,TEM-1,beta-lactamase_2500,P62593,0.281386,NO,261,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.361275,0.0123091,0.281386 beta-lactamase_2500_G142F,beta-lactamase_2500_142,TEM-1,beta-lactamase_2500,P62593,0.281429,NO,142,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.707,-4.29,3.583,,0.034,,p,0.29,-0.64,1.883,,64.69,OOO,-0.834,0.361275,0.00060149,0.281429 beta-lactamase_625_A278P,beta-lactamase_625_278,TEM-1,beta-lactamase_625,P62593,0.281445,NO,278,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.213352,0.0310297,0.281445 beta-lactamase_2500_L284P,beta-lactamase_2500_284,TEM-1,beta-lactamase_2500,P62593,0.281447,NO,284,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.361275,0.0686156,0.281447 beta-lactamase_625_C75K,beta-lactamase_625_75,TEM-1,beta-lactamase_625,P62593,0.281447,NO,75,C,K,CK,Special,PositiveCharge,5.07,9.74,4.67,202,121,146,25,108.5,168.6,60.1,-1.245,-3.786,2.541,,,H,A,0.46,-0.87,2.141,,50,HOO,-1.24333,0.213352,0.0034616,0.281447 beta-lactamase_2500_R220E,beta-lactamase_2500_220,TEM-1,beta-lactamase_2500,P62593,0.28149,NO,220,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-0.942,-3.264,2.322,,0.295,I,A,1.2,-0.76,2.175,,74.48,HBP,-1.33633,0.361275,0.00232421,0.28149 beta-lactamase_E35Y,beta-lactamase_35,TEM-1,beta-lactamase,P62593,0.281548,NO,35,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-0.869,-4.211,3.342,5.10723,0.15,H,A,0.52,0.21,1.081,,46.85,HAA,-1.88667,0.221079,0.00174441,0.281548 beta-lactamase_625_V259E,beta-lactamase_625_259,TEM-1,beta-lactamase_625,P62593,0.281556,NO,259,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.213352,0.0070773,0.281556 kka2_1:1_A34C,kka2_1:1_34,Kka2,kka2_1:1,P00552,0.281572,NO,34,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.928,-4.523,3.595,,0.417,.,B,0.46,2.29,0.262,,52.27,AHH,-1.747,0.520039,0.00343484,0.281572 beta-lactamase_625_C75R,beta-lactamase_625_75,TEM-1,beta-lactamase_625,P62593,0.2816,NO,75,C,R,CR,Special,PositiveCharge,5.07,6.34148,1.27148,180,121,174,53,108.5,173.4,64.9,-1.245,-4.065,2.82,,,H,A,0.46,-0.87,2.141,,50,HOO,-1.24333,0.213352,0.0034616,0.2816 WW_domain_T182H,WW_domain_182,Yap65,WW_domain,P46937,0.281633,NO,182,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.149,-4.457,3.308,6.20597,,,,,,,,,BPP,-1.483,0.153962,0.00294574,0.281633 kka2_1:1_Q136F,kka2_1:1_136,Kka2,kka2_1:1,P00552,0.281716,NO,136,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-3.021,-4.399,1.378,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.520039,0.00624149,0.281716 hsp90_S586F,hsp90_586,hsp90,hsp90,P02829,0.281721,NO,586,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.764,-3.22,0,4.65438,,,B,0.93,0.15,,,,HPH,-3.157,0.368192,0.000222939,0.281721 kka2_1:1_L174N,kka2_1:1_174,Kka2,kka2_1:1,P00552,0.281766,NO,174,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.952,-4.185,3.233,,,H,A,0.55,-0.31,13.276,13.276,51.89,BHB,-2.08533,0.520039,0.00438501,0.281766 beta-lactamase_S104Q,beta-lactamase_104,TEM-1,beta-lactamase,P62593,0.281797,NO,104,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.015,-3.815,2.8,4.92365,0.04,,b,0.82,0.57,4.02,,63.29,HPO,-1.05267,0.221079,0.00218083,0.281797 kka2_1:8_I228A,kka2_1:8_228,Kka2,kka2_1:8,P00552,0.281818,NO,228,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.142,-3.138,1.996,,,H,A,1.52,-1.2,1.521,,71.59,AHH,-1.54633,0.100394,0.00458834,0.281818 kka2_1:8_I228A,kka2_1:8_228,Kka2,kka2_1:8,P00552,0.281818,NO,228,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.142,-3.138,1.996,,,H,A,1.52,-1.2,1.521,,71.59,AHH,-1.54633,0.100394,0.00458834,0.281818 kka2_1:1_V80I,kka2_1:1_80,Kka2,kka2_1:1,P00552,0.281894,NO,80,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.144,-1.887,0.743,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.520039,0.00488211,0.281894 kka2_1:2_K50H,kka2_1:2_50,Kka2,kka2_1:2,P00552,0.281901,NO,50,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-0.833,-4.481,3.648,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.295029,0.00138626,0.281901 kka2_1:1_L212F,kka2_1:1_212,Kka2,kka2_1:1,P00552,0.281902,NO,212,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.904,-3.768,2.864,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.520039,0.0031426,0.281902 kka2_1:4_A34L,kka2_1:4_34,Kka2,kka2_1:4,P00552,0.281919,NO,34,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.928,-3.244,2.316,,0.417,.,B,0.46,2.29,0.262,,52.27,AHH,-1.747,0.168804,0.00343484,0.281919 kka2_1:8_W236E,kka2_1:8_236,Kka2,kka2_1:8,P00552,0.281964,NO,236,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-1.363,-3.989,2.626,,0.303,H,A,1.51,-0.76,1.87,,48.48,AHH,-1.81267,0.100394,0.0088796,0.281964 kka2_1:8_W236E,kka2_1:8_236,Kka2,kka2_1:8,P00552,0.281964,NO,236,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-1.363,-3.989,2.626,,0.303,H,A,1.51,-0.76,1.87,,48.48,AHH,-1.81267,0.100394,0.0088796,0.281964 kka2_1:1_L39W,kka2_1:1_39,Kka2,kka2_1:1,P00552,0.281994,NO,39,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.223,-5.273,4.05,,,E,B,0.55,-1.21,0.925,,71.59,BHP,-1.69167,0.520039,0.00493618,0.281994 beta-lactamase_2500_T179R,beta-lactamase_2500_179,TEM-1,beta-lactamase_2500,P62593,0.282108,NO,179,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.085,-3.749,2.664,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.361275,0.00226045,0.282108 kka2_1:8_D190M,kka2_1:8_190,Kka2,kka2_1:8,P00552,0.282111,NO,190,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.708,-4.958,4.25,,0.213,S,b,0.29,-0.82,,,,OAH,-0.711667,0.100394,0.00247989,0.282111 kka2_1:8_D190M,kka2_1:8_190,Kka2,kka2_1:8,P00552,0.282111,NO,190,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.708,-4.958,4.25,,0.213,S,b,0.29,-0.82,,,,OAH,-0.711667,0.100394,0.00247989,0.282111 kka2_1:8_F133Q,kka2_1:8_133,Kka2,kka2_1:8,P00552,0.282111,NO,133,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-0.871,-4.345,3.474,,0.178,,B,1.62,0.43,1.816,,42.42,OHA,-0.871667,0.100394,0.00182168,0.282111 kka2_1:8_F133Q,kka2_1:8_133,Kka2,kka2_1:8,P00552,0.282111,NO,133,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-0.871,-4.345,3.474,,0.178,,B,1.62,0.43,1.816,,42.42,OHA,-0.871667,0.100394,0.00182168,0.282111 beta-lactamase_2500_A246E,beta-lactamase_2500_246,TEM-1,beta-lactamase_2500,P62593,0.282112,NO,246,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.121,-3.906,1.785,,0.01,E,B,0.46,-1.01,0.753,,73.78,HHH,-1.55633,0.361275,0.00569458,0.282112 kka2_1:1_L39N,kka2_1:1_39,Kka2,kka2_1:1,P00552,0.282139,NO,39,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.223,-4.209,2.986,,,E,B,0.55,-1.21,0.925,,71.59,BHP,-1.69167,0.520039,0.00493618,0.282139 kka2_1:4_F133M,kka2_1:4_133,Kka2,kka2_1:4,P00552,0.282151,NO,133,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-0.871,-4.327,3.456,,0.178,.,B,0.58,0.43,0.786,,42.42,OHA,-0.871667,0.168804,0.00182168,0.282151 kka2_1:1_I221E,kka2_1:1_221,Kka2,kka2_1:1,P00552,0.282203,NO,221,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.739,-4.003,2.264,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.520039,0.00945908,0.282203 beta-lactamase_2500_K232D,beta-lactamase_2500_232,TEM-1,beta-lactamase_2500,P62593,0.282211,NO,232,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.012,-3.566,2.554,,,E,B,2.34,-1.1,3.048,,65.03,ABP,-1.238,0.361275,0.00313441,0.282211 kka2_1:1_V185S,kka2_1:1_185,Kka2,kka2_1:1,P00552,0.28223,NO,185,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.045,-3.595,2.55,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.520039,0.00367031,0.28223 Ubiquitin_G75H,Ubiquitin_75,Uba1,Ubiquitin,P0CG48,0.282258,NO,75,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.613,-4.692,3.079,5.44099,0.552,T,A,0.73,0.9,4.017,,34.31,BOO,-1.66767,0.205827,0.000712673,0.282258 Ubiquitin_G75Y,Ubiquitin_75,Uba1,Ubiquitin,P0CG48,0.282258,NO,75,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.613,-3.107,1.494,5.44099,0.552,T,A,0.73,0.9,4.017,,34.31,BOO,-1.66767,0.205827,0.000712673,0.282258 Ubiquitin_I44N,Ubiquitin_44,Uba1,Ubiquitin,P0CG48,0.282258,NO,44,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.566,-2.851,1.285,4.71256,,E,B,0.27,-1.17,5.26,,39.71,HHH,-1.38567,0.205827,0.000613305,0.282258 Ubiquitin_I44R,Ubiquitin_44,Uba1,Ubiquitin,P0CG48,0.282258,NO,44,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.566,-4.007,2.441,4.71256,,E,B,0.27,-1.17,5.26,,39.71,HHH,-1.38567,0.205827,0.000613305,0.282258 Ubiquitin_L43A,Ubiquitin_43,Uba1,Ubiquitin,P0CG48,0.282258,NO,43,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.269,-3.127,1.858,4.8799,,E,B,1.75,-1.17,10.246,10.246,53.87,BHH,-1.46867,0.205827,0.000572481,0.282258 Ubiquitin_L71Q,Ubiquitin_71,Uba1,Ubiquitin,P0CG48,0.282258,NO,71,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.647,-4.129,2.482,5.02588,0.591,E,B,2.89,-0.69,4.365,,34.31,HHB,-1.85167,0.205827,0.000949314,0.282258 Ubiquitin_Q49P,Ubiquitin_49,Uba1,Ubiquitin,P0CG48,0.282258,NO,49,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-1.941,-2.94,0.999,5.05026,0.403,E,B,,-0.59,,,,BPH,-1.49467,0.205827,0.000613067,0.282258 Ubiquitin_R74A,Ubiquitin_74,Uba1,Ubiquitin,P0CG48,0.282258,NO,74,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.739,-2.637,0.898,5.6462,0.838,T,A,0.98,3.15,9.119,9.119,34.31,HBO,-1.71767,0.205827,0.000894236,0.282258 beta-lactamase_156_V260W,beta-lactamase_156_260,TEM-1,beta-lactamase_156,P62593,0.282298,NO,260,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.111618,0.00471757,0.282298 beta-lactamase_625_L136S,beta-lactamase_625_136,TEM-1,beta-lactamase_625,P62593,0.282336,NO,136,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.232,-3.705,2.473,,,H,A,0.55,-0.34,0.336,,48.95,HHH,-1.088,0.213352,0.00442304,0.282336 beta-lactamase_2500_P181G,beta-lactamase_2500_181,TEM-1,beta-lactamase_2500,P62593,0.282497,NO,181,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.813,-3.321,2.508,,,H,A,0.52,-1.14,1.946,,61.54,HOH,-1.795,0.361275,0.000703122,0.282497 kka2_1:1_F264K,kka2_1:1_264,Kka2,kka2_1:1,P00552,0.282501,NO,264,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.02,-3.94,2.92,,0.296,.,?,0.58,0.02,2.303,,71.59,HHNA,-0.9655,0.520039,,0.282501 beta-lactamase_625_L167F,beta-lactamase_625_167,TEM-1,beta-lactamase_625,P62593,0.282538,NO,167,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.138,-3.813,2.675,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.213352,0.00303566,0.282538 kka2_1:1_P12I,kka2_1:1_12,Kka2,kka2_1:1,P00552,0.282601,NO,12,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.853,-3.96,3.107,,,.,B,0.52,1.25,0.261,,48.11,POH,-1.80767,0.520039,0.00500011,0.282601 kka2_1:1_C192L,kka2_1:1_192,Kka2,kka2_1:1,P00552,0.282653,NO,192,C,L,CL,Special,Hydrophobic,5.07,9.7088,4.6388,198,121,131,10,108.5,166.7,58.2,-1.067,-3.26,2.193,,0.095,.,B,0.46,-0.75,2.749,,50,HOH,-0.960333,0.520039,0.00485428,0.282653 beta-lactamase_L55P,beta-lactamase_55,TEM-1,beta-lactamase,P62593,0.28276,NO,55,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.86,-4.226,2.366,,0.372,E,A,1.07,-0.36,1.423,,63.99,HHA,-2.247,0.221079,0.00403741,0.28276 beta-lactamase_156_G236Y,beta-lactamase_156_236,TEM-1,beta-lactamase_156,P62593,0.282762,NO,236,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.784,-4.387,3.603,,0.241,,b,0.29,-0.59,1.883,,64.69,HOO,-1.025,0.111618,0.00162372,0.282762 kka2_1:1_A14L,kka2_1:1_14,Kka2,kka2_1:1,P00552,0.282771,NO,14,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.837,-3.498,1.661,,0.728,G,A,0.46,0.7,1.17,,71.59,HHH,-1.82567,0.520039,0.00706614,0.282771 kka2_1:2_F48H,kka2_1:2_48,Kka2,kka2_1:2,P00552,0.282815,NO,48,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.453,-4.549,3.096,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.295029,0.00475422,0.282815 kka2_1:2_P76Y,kka2_1:2_76,Kka2,kka2_1:2,P00552,0.282835,NO,76,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.449,-4.443,2.994,,0.331,.,B,0.52,-0.41,0.345,,63.64,HOO,-1.662,0.295029,0.00625685,0.282835 kka2_1:2_G245F,kka2_1:2_245,Kka2,kka2_1:2,P00552,0.282848,NO,245,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.812,-4.364,3.552,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.295029,0.00683899,0.282848 beta-lactamase_2500_M115D,beta-lactamase_2500_115,TEM-1,beta-lactamase_2500,P62593,0.282849,NO,115,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.389,-4.023,2.634,,0.019,E,B,0.55,0.08,3.261,,69.58,OHP,-1.25433,0.361275,0.0034337,0.282849 kka2_1:2_V113Y,kka2_1:2_113,Kka2,kka2_1:2,P00552,0.282953,NO,113,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.233,-4.11,2.877,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.295029,0.00650191,0.282953 kka2_1:1_I246K,kka2_1:1_246,Kka2,kka2_1:1,P00552,0.282962,NO,246,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-2.008,-3.871,1.863,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.520039,0.0139479,0.282962 kka2_1:2_R253P,kka2_1:2_253,Kka2,kka2_1:2,P00552,0.282966,NO,253,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.356,-3.924,2.568,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.295029,0.0144195,0.282966 kka2_1:4_T225K,kka2_1:4_225,Kka2,kka2_1:4,P00552,0.283046,NO,225,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.393,-3.78,1.387,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.168804,0.0113598,0.283046 beta-lactamase_625_T178F,beta-lactamase_625_178,TEM-1,beta-lactamase_625,P62593,0.283072,NO,178,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-0.791,-4.067,3.276,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.213352,0.000684366,0.283072 beta-lactamase_0_I171K,beta-lactamase_0_171,TEM-1,beta-lactamase_0,P62593,0.283096,NO,171,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-2.431,-2.528,0.097,,0.361,,B,0.48,0.53,16.954,16.954,77.62,HHO,-1.55533,0.0500837,0.00623355,0.283096 kka2_1:1_P167D,kka2_1:1_167,Kka2,kka2_1:1,P00552,0.283126,NO,167,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-2.403,-3.015,0.612,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.520039,0.00543203,0.283126 beta-lactamase_625_L73K,beta-lactamase_625_73,TEM-1,beta-lactamase_625,P62593,0.283214,NO,73,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.507,-3.846,2.339,,,H,A,0.55,-0.64,2.933,,67.83,HHH,-1.487,0.213352,0.00488983,0.283214 kka2_1:1_D190H,kka2_1:1_190,Kka2,kka2_1:1,P00552,0.283221,NO,190,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.708,-4.483,3.775,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.520039,0.00247989,0.283221 kka2_1:1_G181W,kka2_1:1_181,Kka2,kka2_1:1,P00552,0.283239,NO,181,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-2.698,-5.561,2.863,,0.379,S,B,0.75,0.78,15.356,15.356,71.59,AOA,-2.21,0.520039,0.00728319,0.283239 beta-lactamase_2500_D161Y,beta-lactamase_2500_161,TEM-1,beta-lactamase_2500,P62593,0.283245,NO,161,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.891,-4.387,3.496,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.361275,0.000897697,0.283245 kka2_1:1_Y244N,kka2_1:1_244,Kka2,kka2_1:1,P00552,0.283248,NO,244,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-0.775,-3.926,3.151,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.520039,0.00453187,0.283248 beta-lactamase_625_Y262Q,beta-lactamase_625_262,TEM-1,beta-lactamase_625,P62593,0.283381,NO,262,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.213352,0.00853516,0.283381 beta-lactamase_625_T158C,beta-lactamase_625_158,TEM-1,beta-lactamase_625,P62593,0.283398,NO,158,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.116,-4.748,3.632,,0.036,,B,0.22,-0.85,3.771,,69.58,HPB,-1.269,0.213352,0.00341825,0.283398 kka2_1:1_V46I,kka2_1:1_46,Kka2,kka2_1:1,P00552,0.283433,NO,46,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-2.62,-3.923,1.303,,0.192,.,B,0.44,-1.12,20.149,20.149,92.05,OHH,-1.88633,0.520039,0.00631301,0.283433 kka2_1:2_V97Y,kka2_1:2_97,Kka2,kka2_1:2,P00552,0.283438,NO,97,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.453,-4.124,2.671,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.295029,0.00737869,0.283438 kka2_1:4_G213Y,kka2_1:4_213,Kka2,kka2_1:4,P00552,0.283478,NO,213,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.596,-4.416,3.82,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.168804,0.00187654,0.283478 kka2_1:1_F48R,kka2_1:1_48,Kka2,kka2_1:1,P00552,0.283511,NO,48,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.453,-4.265,2.812,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.520039,0.00475422,0.283511 beta-lactamase_2500_E35C,beta-lactamase_2500_35,TEM-1,beta-lactamase_2500,P62593,0.283518,NO,35,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-0.869,-5.31,4.441,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.361275,0.00174441,0.283518 kka2_1:4_K50I,kka2_1:4_50,Kka2,kka2_1:4,P00552,0.283521,NO,50,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-0.833,-4.062,3.229,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.168804,0.00138626,0.283521 kka2_1:4_F256P,kka2_1:4_256,Kka2,kka2_1:4,P00552,0.283565,NO,256,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.49,-4.358,2.868,,,H,A,0.58,-0.78,1.653,,53.03,HHH,-1.423,0.168804,0.0132841,0.283565 kka2_1:8_G30Q,kka2_1:8_30,Kka2,kka2_1:8,P00552,0.28357,NO,30,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.596,-4.153,3.557,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.100394,0.00159208,0.28357 kka2_1:8_G30Q,kka2_1:8_30,Kka2,kka2_1:8,P00552,0.28357,NO,30,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.596,-4.153,3.557,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.100394,0.00159208,0.28357 beta-lactamase_625_M66D,beta-lactamase_625_66,TEM-1,beta-lactamase_625,P62593,0.283596,NO,66,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.362,-4.069,2.707,,0.013,,A,0.55,-0.7,1.659,,73.08,OHH,-1.49567,0.213352,0.00412876,0.283596 kka2_1:4_D261Q,kka2_1:4_261,Kka2,kka2_1:4,P00552,0.283653,NO,261,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.708,-3.703,2.995,,0.146,G,A,0.75,-0.33,,,,HAA,-0.759333,0.168804,0.0224846,0.283653 kka2_1:2_N195F,kka2_1:2_195,Kka2,kka2_1:2,P00552,0.28366,NO,195,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-0.836,-4.344,3.508,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.295029,0.00276134,0.28366 beta-lactamase_2500_W208T,beta-lactamase_2500_208,TEM-1,beta-lactamase_2500,P62593,0.283671,NO,208,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-0.818,-3.646,2.828,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.361275,0.00126609,0.283671 kka2_1:2_V80S,kka2_1:2_80,Kka2,kka2_1:2,P00552,0.283674,NO,80,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.144,-3.612,2.468,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.295029,0.00488211,0.283674 kka2_1:1_V49N,kka2_1:1_49,Kka2,kka2_1:1,P00552,0.283709,NO,49,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.614,-4.184,2.57,,,E,B,0.44,-0.77,3.665,3.665,64.39,HHB,-1.3,0.520039,0.00615685,0.283709 kka2_1:1_V185D,kka2_1:1_185,Kka2,kka2_1:1,P00552,0.283724,NO,185,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.045,-4.011,2.966,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.520039,0.00367031,0.283724 kka2_1:4_L184E,kka2_1:4_184,Kka2,kka2_1:4,P00552,0.283748,NO,184,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.496,-3.868,2.372,,0.489,E,B,1.59,-0.06,4.495,,63.26,AHH,-1.24833,0.168804,0.00518742,0.283748 kka2_1:1_L158K,kka2_1:1_158,Kka2,kka2_1:1,P00552,0.283766,NO,158,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.947,-3.896,1.949,,0.095,.,B,0.55,0.77,7.588,,63.64,AHA,-1.25333,0.520039,0.00529068,0.283766 beta-lactamase_39_M209H,beta-lactamase_39_209,TEM-1,beta-lactamase_39,P62593,0.283844,NO,209,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.442,-4.813,3.371,,,H,A,0.55,-0.97,1.167,,64.69,HHA,-1.52633,0.0495842,0.00625021,0.283844 kka2_1:1_D101K,kka2_1:1_101,Kka2,kka2_1:1,P00552,0.283963,NO,101,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.028,-3.563,2.535,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.520039,0.00423361,0.283963 kka2_1:8_H135K,kka2_1:8_135,Kka2,kka2_1:8,P00552,0.284007,NO,135,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-1.331,-3.419,2.088,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.100394,0.00532566,0.284007 kka2_1:8_H135K,kka2_1:8_135,Kka2,kka2_1:8,P00552,0.284007,NO,135,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-1.331,-3.419,2.088,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.100394,0.00532566,0.284007 beta-lactamase_156_M67R,beta-lactamase_156_67,TEM-1,beta-lactamase_156,P62593,0.284011,NO,67,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-2.231,-3.989,1.758,,0.006,G,P,0.55,-0.81,1.463,,65.03,HHP,-1.502,0.111618,0.00409753,0.284011 beta-lactamase_625_N130K,beta-lactamase_625_130,TEM-1,beta-lactamase_625,P62593,0.28402,NO,130,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-0.798,-3.232,2.434,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.213352,0.000683376,0.28402 kka2_1:2_L103D,kka2_1:2_103,Kka2,kka2_1:2,P00552,0.284035,NO,103,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-2.362,-3.76,1.398,,0.394,T,A,0.55,-0.99,3.499,,63.64,HHP,-1.534,0.295029,0.00574792,0.284035 beta-lactamase_2500_T27C,beta-lactamase_2500_27,TEM-1,beta-lactamase_2500,P62593,0.284079,NO,27,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.905,-4.927,3.022,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.361275,0.00306559,0.284079 kka2_1:1_I254A,kka2_1:1_254,Kka2,kka2_1:1,P00552,0.284124,NO,254,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.933,-2.534,0.601,,0.135,H,A,1.52,-0.6,1.859,,71.59,BHH,-1.668,0.520039,0.0132375,0.284124 beta-lactamase_625_N168Y,beta-lactamase_625_168,TEM-1,beta-lactamase_625,P62593,0.284169,NO,168,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-1.029,-4.205,3.176,,0.113,G,A,0.61,-0.4,1.014,,44.41,HPA,-1.13233,0.213352,0.00288667,0.284169 kka2_1:2_E182N,kka2_1:2_182,Kka2,kka2_1:2,P00552,0.284175,NO,182,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.516,-3.686,2.17,,0.326,,B,1.52,0.75,14.547,14.547,65.53,OAA,-1.806,0.295029,0.00641548,0.284175 kka2_1:4_D127I,kka2_1:4_127,Kka2,kka2_1:4,P00552,0.284203,NO,127,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.364,-4.127,2.763,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.168804,0.00660501,0.284203 kka2_1:4_L107D,kka2_1:4_107,Kka2,kka2_1:4,P00552,0.284204,NO,107,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.238,-3.01,1.772,,0.197,.,B,0.55,-1.1,0.398,,71.59,BHH,-2.143,0.168804,0.00561937,0.284204 beta-lactamase_625_T178D,beta-lactamase_625_178,TEM-1,beta-lactamase_625,P62593,0.284238,NO,178,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-0.791,-3.469,2.678,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.213352,0.000684366,0.284238 kka2_1:4_F240P,kka2_1:4_240,Kka2,kka2_1:4,P00552,0.284239,NO,240,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-0.911,-4.356,3.445,,,H,A,0.58,-1.21,5.798,,50.38,BHH,-1.67267,0.168804,0.00552543,0.284239 Pab1_I152Y,Pab1_152,Pab1,Pab1,P04147,0.284298,NO,152,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.345,-3.83,2.485,,0.165,E,B,1.23,-0.71,1.288,,71.4,AHH,-1.59433,0.175299,0.000740963,0.284298 beta-lactamase_2500_R202P,beta-lactamase_2500_202,TEM-1,beta-lactamase_2500,P62593,0.284335,NO,202,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.292,-3.859,2.567,,0.188,H,A,1.2,0.62,3.734,,77.62,PBP,-1.54767,0.361275,0.00321899,0.284335 beta-lactamase_V117G,beta-lactamase_117,TEM-1,beta-lactamase,P62593,0.284339,NO,117,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.53,-3.828,2.298,5.33594,,H,A,1.19,-0.34,1.182,,65.03,PHB,-1.741,0.221079,0.00467906,0.284339 kka2_1:1_D216F,kka2_1:1_216,Kka2,kka2_1:1,P00552,0.284352,NO,216,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.785,-4.288,3.503,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.520039,0.00229969,0.284352 hsp90_S586I,hsp90_586,hsp90,hsp90,P02829,0.284371,NO,586,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.764,-2.939,0,4.65438,,,B,0.93,0.15,,,,HPH,-3.157,0.368192,0.000222939,0.284371 beta-lactamase_V78K,beta-lactamase_78,TEM-1,beta-lactamase,P62593,0.284373,NO,78,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.459,-3.849,2.39,4.79197,,H,A,0.96,-0.47,1.132,,63.64,HHH,-1.17833,0.221079,0.00492501,0.284373 kka2_1:1_I228A,kka2_1:1_228,Kka2,kka2_1:1,P00552,0.284382,NO,228,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.142,-3.138,1.996,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.520039,0.00458834,0.284382 kka2_1:1_L60Q,kka2_1:1_60,Kka2,kka2_1:1,P00552,0.284404,NO,60,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.997,-4.233,3.236,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.520039,0.00262176,0.284404 beta-lactamase_625_C121Q,beta-lactamase_625_121,TEM-1,beta-lactamase_625,P62593,0.28441,NO,121,C,Q,CQ,Special,Polar,5.07,6.24429,1.17429,154,121,146,25,108.5,143.8,35.3,-0.953,-4.222,3.269,,,H,A,0.46,-0.81,1.143,,63.29,HOP,-1.46767,0.213352,0.000744322,0.28441 beta-lactamase_156_V31P,beta-lactamase_156_31,TEM-1,beta-lactamase_156,P62593,0.284452,NO,31,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.822,-4.128,2.306,,,H,A,0.44,-0.46,4.126,,73.78,BHB,-2.03767,0.111618,0.00478065,0.284452 kka2_1:2_L107R,kka2_1:2_107,Kka2,kka2_1:2,P00552,0.284461,NO,107,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.238,-4.11,2.872,,0.197,,B,1.59,-1.1,2.68,,71.59,BHH,-2.143,0.295029,0.00561937,0.284461 kka2_1:2_A41F,kka2_1:2_41,Kka2,kka2_1:2,P00552,0.28453,NO,41,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.879,-3.42,1.541,,0.184,.,B,0.46,-0.96,24.451,24.451,64.39,PHP,-2.477,0.295029,0.00543332,0.28453 kka2_1:1_L170I,kka2_1:1_170,Kka2,kka2_1:1,P00552,0.284539,NO,170,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.28,-2.562,1.282,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.520039,0.00730791,0.284539 kka2_1:1_M116L,kka2_1:1_116,Kka2,kka2_1:1,P00552,0.284564,NO,116,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-2.482,-1.52,-0.962,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.520039,0.00745147,0.284564 kka2_1:8_A222F,kka2_1:8_222,Kka2,kka2_1:8,P00552,0.284588,NO,222,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.725,-4.095,3.37,,,H,A,1.04,-1.21,,,,HHH,-1.10833,0.100394,0.00207657,0.284588 kka2_1:8_A222F,kka2_1:8_222,Kka2,kka2_1:8,P00552,0.284588,NO,222,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.725,-4.095,3.37,,,H,A,1.04,-1.21,,,,HHH,-1.10833,0.100394,0.00207657,0.284588 kka2_1:1_F203W,kka2_1:1_203,Kka2,kka2_1:1,P00552,0.284611,NO,203,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-0.911,-4.558,3.647,,0.26,E,B,0.58,-0.92,7.323,,63.64,BHP,-1.34167,0.520039,0.00318738,0.284611 Pab1_H172V,Pab1_172,Pab1,Pab1,P04147,0.284615,NO,172,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-1.21,-3.571,2.361,,0.076,E,B,0.35,-0.87,,,,HBH,-1.26667,0.175299,0.000296642,0.284615 kka2_1:1_Q155N,kka2_1:1_155,Kka2,kka2_1:1,P00552,0.284631,NO,155,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.606,-3.65,1.044,,0.525,T,A,0.4,1.49,4.415,,63.64,APA,-1.726,0.520039,0.00641853,0.284631 kka2_1:1_L103W,kka2_1:1_103,Kka2,kka2_1:1,P00552,0.28464,NO,103,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-2.362,-5.448,3.086,,0.394,T,A,0.55,-0.99,4.121,,63.64,HHP,-1.534,0.520039,0.00574792,0.28464 beta-lactamase_2500_L219S,beta-lactamase_2500_219,TEM-1,beta-lactamase_2500,P62593,0.284683,NO,219,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.313,-3.686,2.373,,,I,A,0.55,-0.51,35.994,35.994,74.48,HHB,-1.21533,0.361275,0.00664345,0.284683 PSD95pdz3_L379P,PSD95pdz3_379,PSD95pdz3,PSD95pdz3,P31016,0.284724,NO,379,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.347,-3.786,2.439,5.37777,,,,,16.8762,,,,HHB,-1.35667,0.0758425,0.00029733,0.284724 kka2_1:1_I246A,kka2_1:1_246,Kka2,kka2_1:1,P00552,0.284758,NO,246,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-2.008,-2.246,0.238,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.520039,0.0139479,0.284758 kka2_1:1_R211W,kka2_1:1_211,Kka2,kka2_1:1,P00552,0.284785,NO,211,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-0.899,-2.964,2.065,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.520039,0.00204888,0.284785 kka2_1:1_A150F,kka2_1:1_150,Kka2,kka2_1:1,P00552,0.284804,NO,150,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.949,-4.228,3.279,,0.544,T,A,0.46,1.34,2.333,,63.26,AHO,-1.272,0.520039,0.0045009,0.284804 kka2_1:1_D156W,kka2_1:1_156,Kka2,kka2_1:1,P00552,0.28487,NO,156,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.696,-5.547,3.851,,0.884,T,A,0.75,1.87,1.044,,65.53,PAA,-1.765,0.520039,0.00926998,0.28487 kka2_1:8_I207D,kka2_1:8_207,Kka2,kka2_1:8,P00552,0.284879,NO,207,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.175,-4.057,2.882,,0.293,,B,1.52,-1.12,1.306,,56.06,HHA,-1.07733,0.100394,0.00611824,0.284879 kka2_1:8_I207D,kka2_1:8_207,Kka2,kka2_1:8,P00552,0.284879,NO,207,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.175,-4.057,2.882,,0.293,,B,1.52,-1.12,1.306,,56.06,HHA,-1.07733,0.100394,0.00611824,0.284879 kka2_1:8_V113W,kka2_1:8_113,Kka2,kka2_1:8,P00552,0.284879,NO,113,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.233,-5.432,4.199,,0.008,H,A,1.48,-1.17,1.254,,52.27,BHP,-2.08367,0.100394,0.00650191,0.284879 kka2_1:8_V113W,kka2_1:8_113,Kka2,kka2_1:8,P00552,0.284879,NO,113,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.233,-5.432,4.199,,0.008,H,A,1.48,-1.17,1.254,,52.27,BHP,-2.08367,0.100394,0.00650191,0.284879 kka2_1:2_C209E,kka2_1:2_209,Kka2,kka2_1:2,P00552,0.284917,NO,209,C,E,CE,Special,negativeCharge,5.07,3.22,-1.85,170,121,147,26,108.5,138.4,29.9,-0.906,-4.141,3.235,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.295029,0.00260862,0.284917 kka2_1:2_L193Q,kka2_1:2_193,Kka2,kka2_1:2,P00552,0.284929,NO,193,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.983,-2.972,1.989,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.295029,0.00480179,0.284929 beta-lactamase_625_S241L,beta-lactamase_625_241,TEM-1,beta-lactamase_625,P62593,0.284969,NO,241,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.213352,0.00452736,0.284969 PSD95pdz3_G324L,PSD95pdz3_324,PSD95pdz3,PSD95pdz3,P31016,0.284974,NO,324,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.008,-3.49,2.482,4.98881,,,,,10.4525,,,,HOH,-1.293,0.0758425,0.00103462,0.284974 kka2_1:1_G99E,kka2_1:1_99,Kka2,kka2_1:1,P00552,0.284999,NO,99,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.596,-3.693,3.097,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.520039,0.00186055,0.284999 kka2_1:1_A71D,kka2_1:1_71,Kka2,kka2_1:1,P00552,0.285007,NO,71,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.824,-3.702,1.878,,0.553,H,A,0.46,0.08,9.788,,64.39,HHP,-1.74033,0.520039,0.00727707,0.285007 kka2_1:2_E111N,kka2_1:2_111,Kka2,kka2_1:2,P00552,0.285011,NO,111,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.28,-3.19,0.91,,0.155,H,A,1.52,-1.14,2.792,,65.53,HAB,-2.27833,0.295029,0.00746789,0.285011 kka2_1:4_G245F,kka2_1:4_245,Kka2,kka2_1:4,P00552,0.285022,NO,245,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.812,-4.364,3.552,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.168804,0.00683899,0.285022 kka2_1:1_L103A,kka2_1:1_103,Kka2,kka2_1:1,P00552,0.285023,NO,103,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-2.362,-1.403,-0.959,,0.394,T,A,0.55,-0.99,4.121,,63.64,HHP,-1.534,0.520039,0.00574792,0.285023 kka2_1:8_K112H,kka2_1:8_112,Kka2,kka2_1:8,P00552,0.285024,NO,112,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-2.491,-4.863,2.372,,0.076,H,A,1.3,-1.37,10.58,10.58,56.06,ABH,-2.00133,0.100394,0.00645389,0.285024 kka2_1:8_K112H,kka2_1:8_112,Kka2,kka2_1:8,P00552,0.285024,NO,112,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-2.491,-4.863,2.372,,0.076,H,A,1.3,-1.37,10.58,10.58,56.06,ABH,-2.00133,0.100394,0.00645389,0.285024 kka2_1:8_K112W,kka2_1:8_112,Kka2,kka2_1:8,P00552,0.285024,NO,112,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-2.491,-5.516,3.025,,0.076,H,A,1.3,-1.37,10.58,10.58,56.06,ABH,-2.00133,0.100394,0.00645389,0.285024 kka2_1:8_K112W,kka2_1:8_112,Kka2,kka2_1:8,P00552,0.285024,NO,112,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-2.491,-5.516,3.025,,0.076,H,A,1.3,-1.37,10.58,10.58,56.06,ABH,-2.00133,0.100394,0.00645389,0.285024 kka2_1:2_G213A,kka2_1:2_213,Kka2,kka2_1:2,P00552,0.285034,NO,213,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.596,-2.881,2.285,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.295029,0.00187654,0.285034 kka2_1:1_F37Q,kka2_1:1_37,Kka2,kka2_1:1,P00552,0.285052,NO,37,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.427,-4.273,2.846,,0.219,E,B,0.58,-0.25,18.64,18.64,64.39,HHB,-1.17733,0.520039,0.00586193,0.285052 beta-lactamase_2500_L284G,beta-lactamase_2500_284,TEM-1,beta-lactamase_2500,P62593,0.285077,NO,284,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.361275,0.0686156,0.285077 kka2_1:1_G205D,kka2_1:1_205,Kka2,kka2_1:1,P00552,0.285138,NO,205,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.596,-3.497,2.901,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.520039,0.00221855,0.285138 beta-lactamase_2500_L167E,beta-lactamase_2500_167,TEM-1,beta-lactamase_2500,P62593,0.285148,NO,167,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.138,-3.783,2.645,,0.015,G,A,0.55,-0.63,7.813,,64.69,AHP,-1.30767,0.361275,0.00303566,0.285148 beta-lactamase_D155Q,beta-lactamase_155,TEM-1,beta-lactamase,P62593,0.285167,NO,155,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.889,-3.667,2.778,4.92265,0.049,,B,0.45,-0.9,3.208,,64.69,OAB,-1.62267,0.221079,0.00135315,0.285167 beta-lactamase_L100D,beta-lactamase_100,TEM-1,beta-lactamase,P62593,0.285167,NO,100,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.218,-4.132,2.914,5.60291,0.343,,B,1.3,0.13,1.173,,63.29,AHH,-1.23467,0.221079,0.00413885,0.285167 beta-lactamase_L120N,beta-lactamase_120,TEM-1,beta-lactamase,P62593,0.285167,NO,120,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.044,-4.027,2.983,5.11974,,H,A,1.3,-1.13,1.988,,64.69,AHO,-1.13633,0.221079,0.00143563,0.285167 beta-lactamase_L160W,beta-lactamase_160,TEM-1,beta-lactamase,P62593,0.285167,NO,160,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.977,-5.194,4.217,5.32068,0.022,,B,1.75,-0.6,0.895,,44.41,BHA,-0.936,0.221079,0.00193775,0.285167 beta-lactamase_T116W,beta-lactamase_116,TEM-1,beta-lactamase,P62593,0.285167,NO,116,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.28,-5.356,4.076,4.78335,0.115,E,B,0.69,-0.12,0.343,,67.48,HPH,-1.39967,0.221079,0.00336175,0.285167 kka2_1:4_R211K,kka2_1:4_211,Kka2,kka2_1:4,P00552,0.285188,NO,211,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-0.899,-2.904,2.005,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.168804,0.00204888,0.285188 kka2_1:1_R253E,kka2_1:1_253,Kka2,kka2_1:1,P00552,0.285274,NO,253,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.356,-3.329,1.973,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.520039,0.0144195,0.285274 hsp90_N588K,hsp90_588,hsp90,hsp90,P02829,0.285314,NO,588,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-3.051,-2.835,0,4.61142,0.019,H,A,0.14,0.39,,,,HPH,-3.12167,0.368192,0.000222939,0.285314 kka2_1:8_F171T,kka2_1:8_171,Kka2,kka2_1:8,P00552,0.285314,NO,171,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.326,-3.738,2.412,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.100394,0.00821426,0.285314 kka2_1:8_F171T,kka2_1:8_171,Kka2,kka2_1:8,P00552,0.285314,NO,171,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.326,-3.738,2.412,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.100394,0.00821426,0.285314 beta-lactamase_2500_A185R,beta-lactamase_2500_185,TEM-1,beta-lactamase_2500,P62593,0.28533,NO,185,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.406,-3.963,2.557,,,H,A,0.46,-1.02,2.999,,65.03,HHP,-1.84033,0.361275,0.00467449,0.28533 kka2_1:1_D156F,kka2_1:1_156,Kka2,kka2_1:1,P00552,0.285334,NO,156,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.696,-4.395,2.699,,0.884,T,A,0.75,1.87,1.044,,65.53,PAA,-1.765,0.520039,0.00926998,0.285334 kka2_1:2_W69M,kka2_1:2_69,Kka2,kka2_1:2,P00552,0.285344,NO,69,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-0.859,-4.531,3.672,,0.164,H,A,0.47,0.15,5.074,,38.64,PHH,-1.49967,0.295029,0.0012874,0.285344 beta-lactamase_2500_P65I,beta-lactamase_2500_65,TEM-1,beta-lactamase_2500,P62593,0.285369,NO,65,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.894,-3.716,2.822,,0.098,E,B,0.52,-0.62,0.3,,40.56,HOH,-1.03233,0.361275,0.00152776,0.285369 beta-lactamase_2500_L218W,beta-lactamase_2500_218,TEM-1,beta-lactamase_2500,P62593,0.2854,NO,218,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.391,-5.26,3.869,,,I,b,0.55,-0.53,9.151,9.151,74.48,OHH,-1.58867,0.361275,0.00618274,0.2854 beta-lactamase_2500_T27E,beta-lactamase_2500_27,TEM-1,beta-lactamase_2500,P62593,0.285428,NO,27,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.905,-2.714,0.809,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.361275,0.00306559,0.285428 Pab1_F149G,Pab1_149,Pab1,Pab1,P04147,0.285457,NO,149,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.149,-3.4,2.251,,0.183,T,A,1.33,1.09,,,,HHO,-1.27767,0.175299,0.000325688,0.285457 kka2_1:1_G233Y,kka2_1:1_233,Kka2,kka2_1:1,P00552,0.28555,NO,233,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.748,-4.46,3.712,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.520039,0.00232366,0.28555 kka2_1:1_G213A,kka2_1:1_213,Kka2,kka2_1:1,P00552,0.285553,NO,213,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.596,-2.881,2.285,,,E,b,0.29,-0.4,,,,HOH,-0.920333,0.520039,0.00187654,0.285553 beta-lactamase_156_Y262N,beta-lactamase_156_262,TEM-1,beta-lactamase_156,P62593,0.285572,NO,262,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.111618,0.00853516,0.285572 kka2_1:1_L102Q,kka2_1:1_102,Kka2,kka2_1:1,P00552,0.285601,NO,102,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.804,-4.12,3.316,,,T,A,0.55,-1.17,4.258,,42.42,AHH,-1.398,0.520039,0.00201332,0.285601 kka2_1:8_G30F,kka2_1:8_30,Kka2,kka2_1:8,P00552,0.285603,NO,30,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.596,-4.32,3.724,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.100394,0.00159208,0.285603 kka2_1:8_G30F,kka2_1:8_30,Kka2,kka2_1:8,P00552,0.285603,NO,30,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.596,-4.32,3.724,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.100394,0.00159208,0.285603 hsp90_S586M,hsp90_586,hsp90,hsp90,P02829,0.28562,NO,586,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.764,-3.858,0,4.65438,,,B,0.93,0.15,,,,HPH,-3.157,0.368192,0.000222939,0.28562 kka2_1:1_P194K,kka2_1:1_194,Kka2,kka2_1:1,P00552,0.285645,NO,194,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.846,-3.507,2.661,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.520039,0.00314194,0.285645 beta-lactamase_625_N130I,beta-lactamase_625_130,TEM-1,beta-lactamase_625,P62593,0.285662,NO,130,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-0.798,-4.01,3.212,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.213352,0.000683376,0.285662 beta-lactamase_2500_N130G,beta-lactamase_2500_130,TEM-1,beta-lactamase_2500,P62593,0.285712,NO,130,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-0.798,-2.908,2.11,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.361275,0.000683376,0.285712 kka2_1:1_D250P,kka2_1:1_250,Kka2,kka2_1:1,P00552,0.285713,NO,250,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.015,-3.798,2.783,,0.274,.,b,0.75,-0.46,4.177,,51.89,OAP,-1.83933,0.520039,0.0177103,0.285713 kka2_1:1_H8I,kka2_1:1_8,Kka2,kka2_1:1,P00552,0.285733,NO,8,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-2.759,-2.602,-0.157,,,,,,,16.971,16.971,71.59,HBH,-2.25467,0.520039,0.00256422,0.285733 beta-lactamase_2500_L120T,beta-lactamase_2500_120,TEM-1,beta-lactamase_2500,P62593,0.285746,NO,120,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.044,-3.547,2.503,,,H,A,0.55,-1.13,2.48,,64.69,AHO,-1.13633,0.361275,0.00143563,0.285746 kka2_1:1_I221H,kka2_1:1_221,Kka2,kka2_1:1,P00552,0.285805,NO,221,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.739,-5.027,3.288,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.520039,0.00945908,0.285805 kka2_1:1_V49H,kka2_1:1_49,Kka2,kka2_1:1,P00552,0.285805,NO,49,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.614,-5.018,3.404,,,E,B,0.44,-0.77,3.665,3.665,64.39,HHB,-1.3,0.520039,0.00615685,0.285805 kka2_1:1_Q219M,kka2_1:1_219,Kka2,kka2_1:1,P00552,0.285817,NO,219,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-0.93,-4.327,3.397,,0.088,H,A,0.4,-0.85,1.917,,50,HPA,-1.05167,0.520039,0.00237913,0.285817 beta-lactamase_39_G43W,beta-lactamase_39_43,TEM-1,beta-lactamase_39,P62593,0.285822,NO,43,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.62,-5.097,4.477,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.0495842,0.00120151,0.285822 kka2_1:1_R258I,kka2_1:1_258,Kka2,kka2_1:1,P00552,0.285825,NO,258,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.626,-3.905,2.279,,0.316,H,A,1.2,-0.85,7.485,7.485,53.03,HBH,-1.25933,0.520039,0.00983174,0.285825 kka2_1:8_D261K,kka2_1:8_261,Kka2,kka2_1:8,P00552,0.285893,NO,261,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.708,-3.485,2.777,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.100394,0.0224846,0.285893 kka2_1:8_D261K,kka2_1:8_261,Kka2,kka2_1:8,P00552,0.285893,NO,261,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.708,-3.485,2.777,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.100394,0.0224846,0.285893 kka2_1:8_V49D,kka2_1:8_49,Kka2,kka2_1:8,P00552,0.285893,NO,49,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.614,-4.094,2.48,,,E,B,1.48,-0.77,1.31,,64.39,HHB,-1.3,0.100394,0.00615685,0.285893 kka2_1:8_V49D,kka2_1:8_49,Kka2,kka2_1:8,P00552,0.285893,NO,49,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.614,-4.094,2.48,,,E,B,1.48,-0.77,1.31,,64.39,HHB,-1.3,0.100394,0.00615685,0.285893 beta-lactamase_625_L192G,beta-lactamase_625_192,TEM-1,beta-lactamase_625,P62593,0.285897,NO,192,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.254,-3.698,2.444,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.213352,0.00558728,0.285897 kka2_1:1_V186C,kka2_1:1_186,Kka2,kka2_1:1,P00552,0.285899,NO,186,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.011,-4.765,3.754,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.520039,0.00409703,0.285899 beta-lactamase_2500_C75W,beta-lactamase_2500_75,TEM-1,beta-lactamase_2500,P62593,0.285943,NO,75,C,W,CW,Special,Hydrophobic,5.07,5.89,0.82,215,121,204,83,108.5,227.8,119.3,-1.245,-5.246,4.001,,,H,A,0.46,-0.87,0.844,,50,HOO,-1.24333,0.361275,0.0034616,0.285943 PSD95pdz3_A376Q,PSD95pdz3_376,PSD95pdz3,PSD95pdz3,P31016,0.285971,NO,376,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.307,-3.581,2.274,4.72134,,,,,17.108,,,,HHH,-1.49567,0.0758425,0.000341232,0.285971 kka2_1:4_F240E,kka2_1:4_240,Kka2,kka2_1:4,P00552,0.285993,NO,240,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-0.911,-3.952,3.041,,,H,A,0.58,-1.21,5.798,,50.38,BHH,-1.67267,0.168804,0.00552543,0.285993 beta-lactamase_39_A185R,beta-lactamase_39_185,TEM-1,beta-lactamase_39,P62593,0.285998,NO,185,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.406,-3.963,2.557,,,H,A,0.46,-1.02,2.68,,65.03,HHP,-1.84033,0.0495842,0.00467449,0.285998 beta-lactamase_625_G249K,beta-lactamase_625_249,TEM-1,beta-lactamase_625,P62593,0.286003,NO,249,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.213352,0.00220169,0.286003 kka2_1:1_F263R,kka2_1:1_263,Kka2,kka2_1:1,P00552,0.286015,NO,263,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-0.911,-4.185,3.274,,0.006,G,A,0.58,-0.12,2.284,,45.83,AHH,-0.92,0.520039,0.0172454,0.286015 beta-lactamase_625_G240T,beta-lactamase_625_240,TEM-1,beta-lactamase_625,P62593,0.28602,NO,240,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.213352,0.00591201,0.28602 beta-lactamase_156_L167E,beta-lactamase_156_167,TEM-1,beta-lactamase_156,P62593,0.286037,NO,167,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.138,-3.783,2.645,,0.015,G,A,0.55,-0.63,0.4,,64.69,AHP,-1.30767,0.111618,0.00303566,0.286037 beta-lactamase_625_S241W,beta-lactamase_625_241,TEM-1,beta-lactamase_625,P62593,0.286066,NO,241,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.213352,0.00452736,0.286066 kka2_1:2_V153S,kka2_1:2_153,Kka2,kka2_1:2,P00552,0.286094,NO,153,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.092,-3.643,2.551,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.295029,0.00501119,0.286094 PSD95pdz3_H372D,PSD95pdz3_372,PSD95pdz3,PSD95pdz3,P31016,0.286095,NO,372,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-1.627,-3.15,1.523,5.5607,,,,,17.008,,,,PBA,-1.63033,0.0758425,0.00040301,0.286095 kka2_1:4_M116G,kka2_1:4_116,Kka2,kka2_1:4,P00552,0.286165,NO,116,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-2.482,-3.754,1.272,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.168804,0.00745147,0.286165 kka2_1:1_E235N,kka2_1:1_235,Kka2,kka2_1:1,P00552,0.286191,NO,235,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.955,-3.12,1.165,,0.631,H,A,1.52,0.12,8.521,,65.53,OAH,-2.07267,0.520039,0.0102806,0.286191 kka2_1:1_E262N,kka2_1:1_262,Kka2,kka2_1:1,P00552,0.286212,NO,262,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-0.829,-3.499,2.67,,0.059,G,A,1.04,-0.18,0.837,,42.42,AAH,-0.816,0.520039,0.0191586,0.286212 kka2_1:2_N195C,kka2_1:2_195,Kka2,kka2_1:2,P00552,0.286223,NO,195,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-0.836,-5.139,4.303,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.295029,0.00276134,0.286223 beta-lactamase_L205Y,beta-lactamase_205,TEM-1,beta-lactamase,P62593,0.286253,NO,205,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.922,-3.727,2.805,5.67023,,H,A,1.3,-0.46,0.678,,42.31,PHH,-1.57767,0.221079,0.00255802,0.286253 Pab1_S154P,Pab1_154,Pab1,Pab1,P04147,0.286294,NO,154,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.146,-3.472,2.326,,0.208,E,B,0.1,-0.75,,,,HPP,-1.408,0.175299,0.000319331,0.286294 Pab1_F170L,Pab1_170,Pab1,Pab1,P04147,0.286314,NO,170,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.269,-2.829,1.56,,0.331,E,B,0.87,-1.31,2.061,,79.72,OHH,-1.06367,0.175299,0.000540225,0.286314 beta-lactamase_625_F70R,beta-lactamase_625_70,TEM-1,beta-lactamase_625,P62593,0.286318,NO,70,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.169,-4.114,2.945,,,H,A,0.58,-1.34,1.14,,63.99,PHB,-0.980667,0.213352,0.00193499,0.286318 kka2_1:1_E161I,kka2_1:1_161,Kka2,kka2_1:1,P00552,0.286329,NO,161,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.581,-3.91,2.329,,0.829,G,A,1.04,2.24,1.612,,92.05,AAB,-1.861,0.520039,0.00760103,0.286329 kka2_1:4_I115W,kka2_1:4_115,Kka2,kka2_1:4,P00552,0.286333,NO,115,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.606,-5.354,3.748,,0.105,H,A,1.52,-1.18,9.996,9.996,65.53,PHH,-2.205,0.168804,0.00836567,0.286333 kka2_1:1_T72Q,kka2_1:1_72,Kka2,kka2_1:1,P00552,0.286362,NO,72,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.38,-2.662,0.282,,0.784,H,A,0.22,0.29,10.43,10.43,65.53,HPP,-2.238,0.520039,0.00750756,0.286362 kka2_1:4_S32P,kka2_1:4_32,Kka2,kka2_1:4,P00552,0.286363,NO,32,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-0.804,-3.683,2.879,,0.768,S,b,0.27,3.75,,,,OPA,-1.74533,0.168804,0.00149998,0.286363 kka2_1:2_T51I,kka2_1:2_51,Kka2,kka2_1:2,P00552,0.286381,NO,51,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.199,-2.59,0.391,,0.05,E,B,0.22,-0.05,13.165,13.165,63.64,BPA,-1.76767,0.295029,0.00628861,0.286381 kka2_1:1_Q26G,kka2_1:1_26,Kka2,kka2_1:1,P00552,0.286461,NO,26,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.18,-2.702,0.522,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.520039,0.00708962,0.286461 kka2_1:1_Q26N,kka2_1:1_26,Kka2,kka2_1:1,P00552,0.286461,NO,26,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.18,-3.808,1.628,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.520039,0.00708962,0.286461 kka2_1:8_H162M,kka2_1:8_162,Kka2,kka2_1:8,P00552,0.286471,NO,162,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-2.319,-4.675,2.356,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.100394,0.00616145,0.286471 kka2_1:8_H162M,kka2_1:8_162,Kka2,kka2_1:8,P00552,0.286471,NO,162,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-2.319,-4.675,2.356,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.100394,0.00616145,0.286471 beta-lactamase_39_L120D,beta-lactamase_39_120,TEM-1,beta-lactamase_39,P62593,0.286499,NO,120,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.044,-4.076,3.032,,,H,A,0.55,-1.13,22.254,22.254,64.69,AHO,-1.13633,0.0495842,0.00143563,0.286499 kka2_1:2_P132K,kka2_1:2_132,Kka2,kka2_1:2,P00552,0.286526,NO,132,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.775,-3.483,2.708,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.295029,0.0018489,0.286526 kka2_1:1_C209H,kka2_1:1_209,Kka2,kka2_1:1,P00552,0.286601,NO,209,C,H,CH,Special,PositiveCharge,5.07,7.59,2.52,174,121,155,34,108.5,153.2,44.7,-0.906,-4.957,4.051,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.520039,0.00260862,0.286601 kka2_1:1_E231V,kka2_1:1_231,Kka2,kka2_1:1,P00552,0.286606,NO,231,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.002,-2.912,0.91,,0.503,H,A,1.04,-0.23,25.629,25.629,63.26,AAH,-2.06267,0.520039,0.00732383,0.286606 kka2_1:1_T130C,kka2_1:1_130,Kka2,kka2_1:1,P00552,0.286635,NO,130,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.392,-3.62,1.228,,0.561,G,A,0.22,0.77,0.5,,92.05,HPO,-1.62633,0.520039,0.00804204,0.286635 kka2_1:2_P132V,kka2_1:2_132,Kka2,kka2_1:2,P00552,0.286683,NO,132,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.775,-3.58,2.805,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.295029,0.0018489,0.286683 beta-lactamase_2500_I280A,beta-lactamase_2500_280,TEM-1,beta-lactamase_2500,P62593,0.286704,NO,280,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.708,-4.017,2.309,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.361275,0.0530888,0.286704 beta-lactamase_2500_W227A,beta-lactamase_2500_227,TEM-1,beta-lactamase_2500,P62593,0.286715,NO,227,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-0.982,-3.46,2.478,,0.272,,B,0.47,-0.29,1.37,,74.48,OHH,-1.595,0.361275,0.00226019,0.286715 kka2_1:1_A41M,kka2_1:1_41,Kka2,kka2_1:1,P00552,0.286774,NO,41,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.879,-3.613,1.734,,0.184,.,B,0.46,-0.96,18.207,18.207,64.39,PHP,-2.477,0.520039,0.00543332,0.286774 beta-lactamase_625_G236H,beta-lactamase_625_236,TEM-1,beta-lactamase_625,P62593,0.286797,NO,236,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.784,-4.704,3.92,,0.241,,b,0.29,-0.59,3.506,,64.69,HOO,-1.025,0.213352,0.00162372,0.286797 kka2_1:1_R140N,kka2_1:1_140,Kka2,kka2_1:1,P00552,0.286832,NO,140,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.351,-3.614,2.263,,0.12,H,A,1.2,0.2,11.345,11.345,53.03,BBH,-1.885,0.520039,0.00430167,0.286832 beta-lactamase_2500_R162M,beta-lactamase_2500_162,TEM-1,beta-lactamase_2500,P62593,0.286838,NO,162,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.016,-4.454,3.438,,0.124,S,B,1.2,-0.37,6.199,,64.69,ABH,-1.25,0.361275,0.000561334,0.286838 kka2_1:1_C131T,kka2_1:1_131,Kka2,kka2_1:1,P00552,0.286878,NO,131,C,T,CT,Special,Polar,5.07,5.6,0.53,149,121,119,-2,108.5,116.1,7.6,-0.831,-3.45,2.619,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.520039,0.00170814,0.286878 beta-lactamase_2500_K232Y,beta-lactamase_2500_232,TEM-1,beta-lactamase_2500,P62593,0.28689,NO,232,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.012,-4.205,3.193,,,E,B,2.34,-1.1,3.048,,65.03,ABP,-1.238,0.361275,0.00313441,0.28689 kka2_1:1_L103K,kka2_1:1_103,Kka2,kka2_1:1,P00552,0.286895,NO,103,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-2.362,-3.65,1.288,,0.394,T,A,0.55,-0.99,4.121,,63.64,HHP,-1.534,0.520039,0.00574792,0.286895 beta-lactamase_625_P224F,beta-lactamase_625_224,TEM-1,beta-lactamase_625,P62593,0.286999,NO,224,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.893,-4.486,3.593,,0.383,,B,0.52,-0.3,1.35,,74.48,HOH,-1.26433,0.213352,0.00189564,0.286999 kka2_1:2_E63Y,kka2_1:2_63,Kka2,kka2_1:2,P00552,0.287039,NO,63,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-0.762,-4.191,3.429,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.295029,0.00118399,0.287039 beta-lactamase_39_L205K,beta-lactamase_39_205,TEM-1,beta-lactamase_39,P62593,0.287055,NO,205,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.922,-3.736,2.814,,,H,A,0.55,-0.46,0.846,,42.31,PHH,-1.57767,0.0495842,0.00255802,0.287055 kka2_1:1_I115F,kka2_1:1_115,Kka2,kka2_1:1,P00552,0.28706,NO,115,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.606,-3.062,1.456,,0.105,H,A,0.48,-1.18,0.878,,65.53,PHH,-2.205,0.520039,0.00836567,0.28706 kka2_1:1_Q27A,kka2_1:1_27,Kka2,kka2_1:1,P00552,0.287144,NO,27,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-1.659,-3.31,1.651,,0.608,.,A,0.64,0.71,0.521,,65.53,PPP,-1.90733,0.520039,0.00595365,0.287144 beta-lactamase_R241D,beta-lactamase_241,TEM-1,beta-lactamase,P62593,0.287176,NO,241,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.433,-2.771,1.338,5.02621,0.094,E,B,0.68,-0.16,1.327,,50,PBO,-1.42967,0.221079,0.00452736,0.287176 kka2_1:1_G189P,kka2_1:1_189,Kka2,kka2_1:1,P00552,0.287204,NO,189,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.596,-3.908,3.312,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.520039,0.00253688,0.287204 beta-lactamase_0_L120P,beta-lactamase_0_120,TEM-1,beta-lactamase_0,P62593,0.287241,NO,120,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.044,-4.17,3.126,,,H,A,0.55,-1.13,1.2,,64.69,AHO,-1.13633,0.0500837,0.00143563,0.287241 kka2_1:1_R44E,kka2_1:1_44,Kka2,kka2_1:1,P00552,0.287247,NO,44,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.062,-2.778,0.716,,0.487,S,B,1.2,-0.35,2.717,,71.59,OBO,-1.80767,0.520039,0.00745043,0.287247 kka2_1:1_V214N,kka2_1:1_214,Kka2,kka2_1:1,P00552,0.287266,NO,214,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.261,-4.229,2.968,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.520039,0.00692782,0.287266 kka2_1:2_R253D,kka2_1:2_253,Kka2,kka2_1:2,P00552,0.287276,NO,253,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.356,-3.762,2.406,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.295029,0.0144195,0.287276 beta-lactamase_0_T126G,beta-lactamase_0_126,TEM-1,beta-lactamase_0,P62593,0.287312,NO,126,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.122,-2.22,1.098,,0.05,H,A,0.22,-0.05,0.705,,44.41,HPH,-1.60467,0.0500837,0.00244552,0.287312 kka2_1:2_D82I,kka2_1:2_82,Kka2,kka2_1:2,P00552,0.287322,NO,82,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.946,-4.04,2.094,,0.341,E,b,0.75,0.52,11.923,11.923,63.64,HAH,-1.98,0.295029,0.00637516,0.287322 kka2_1:1_R121W,kka2_1:1_121,Kka2,kka2_1:1,P00552,0.287358,NO,121,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.552,-5.451,3.899,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.520039,0.00523326,0.287358 beta-lactamase_2500_R59L,beta-lactamase_2500_59,TEM-1,beta-lactamase_2500,P62593,0.287369,NO,59,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.345,-3.484,2.139,,0.329,S,L,1.2,-0.09,3.719,,73.08,HBO,-2.24267,0.361275,0.00318082,0.287369 beta-lactamase_625_N130R,beta-lactamase_625_130,TEM-1,beta-lactamase_625,P62593,0.28737,NO,130,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-0.798,-3.483,2.685,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.213352,0.000683376,0.28737 kka2_1:4_W24N,kka2_1:4_24,Kka2,kka2_1:4,P00552,0.287485,NO,24,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-1.779,-4.301,2.522,,0.477,E,B,1.51,-0.21,2.666,,56.06,AHH,-2.24467,0.168804,0.00631564,0.287485 kka2_1:4_A150P,kka2_1:4_150,Kka2,kka2_1:4,P00552,0.287514,NO,150,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.949,-3.782,2.833,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.168804,0.0045009,0.287514 kka2_1:1_D62A,kka2_1:1_62,Kka2,kka2_1:1,P00552,0.28754,NO,62,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.591,-2.125,0.534,,0.262,H,A,0.75,0.08,10.048,10.048,64.39,PAA,-1.77833,0.520039,0.00744243,0.28754 kka2_1:1_V36S,kka2_1:1_36,Kka2,kka2_1:1,P00552,0.287563,NO,36,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-0.898,-3.684,2.786,,0.292,E,B,0.44,0.21,0.278,,52.27,HHH,-1.484,0.520039,0.00245633,0.287563 beta-lactamase_Y95Q,beta-lactamase_95,TEM-1,beta-lactamase,P62593,0.287581,NO,95,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-1.715,-4.267,2.552,5.67068,0.122,,b,0.96,-0.37,2.341,,77.62,BHP,-2.16167,0.221079,0.00479449,0.287581 beta-lactamase_625_R242W,beta-lactamase_625_242,TEM-1,beta-lactamase_625,P62593,0.287592,NO,242,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.213352,0.00452879,0.287592 kka2_1:1_L158H,kka2_1:1_158,Kka2,kka2_1:1,P00552,0.2876,NO,158,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.947,-4.683,2.736,,0.095,.,B,0.55,0.77,7.588,,63.64,AHA,-1.25333,0.520039,0.00529068,0.2876 kka2_1:1_W24E,kka2_1:1_24,Kka2,kka2_1:1,P00552,0.287618,NO,24,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-1.779,-4.036,2.257,,0.477,E,B,0.47,-0.21,2.375,,56.06,AHH,-2.24467,0.520039,0.00631564,0.287618 kka2_1:1_L70I,kka2_1:1_70,Kka2,kka2_1:1,P00552,0.287745,NO,70,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.017,-2.539,1.522,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.520039,0.00411884,0.287745 hsp90_F583K,hsp90_583,hsp90,hsp90,P02829,0.287791,NO,583,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-3.22,-2.835,0,5.28185,1.112,S,l,1.1,0.87,,,,PHO,-3.003,0.368192,0.000222939,0.287791 kka2_1:2_D250F,kka2_1:2_250,Kka2,kka2_1:2,P00552,0.287793,NO,250,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.015,-4.403,3.388,,0.274,.,b,0.75,-0.46,3.796,,51.89,OAP,-1.83933,0.295029,0.0177103,0.287793 kka2_1:1_E199L,kka2_1:1_199,Kka2,kka2_1:1,P00552,0.287833,NO,199,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.234,-3.058,0.824,,0.508,E,B,1.04,-0.43,3.012,,65.53,HAP,-2.133,0.520039,0.00854122,0.287833 kka2_1:1_R38N,kka2_1:1_38,Kka2,kka2_1:1,P00552,0.287836,NO,38,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.207,-3.763,2.556,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.520039,0.00372499,0.287836 kka2_1:2_L39A,kka2_1:2_39,Kka2,kka2_1:2,P00552,0.287898,NO,39,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.223,-2.615,1.392,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.295029,0.00493618,0.287898 kka2_1:8_F263I,kka2_1:8_263,Kka2,kka2_1:8,P00552,0.287911,NO,263,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-0.911,-3.319,2.408,,0.006,G,A,1.62,-0.12,0.928,,45.83,AHH,-0.92,0.100394,0.0172454,0.287911 kka2_1:8_F263I,kka2_1:8_263,Kka2,kka2_1:8,P00552,0.287911,NO,263,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-0.911,-3.319,2.408,,0.006,G,A,1.62,-0.12,0.928,,45.83,AHH,-0.92,0.100394,0.0172454,0.287911 beta-lactamase_2500_S241I,beta-lactamase_2500_241,TEM-1,beta-lactamase_2500,P62593,0.287924,NO,241,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.361275,0.00452736,0.287924 beta-lactamase_2500_G249R,beta-lactamase_2500_249,TEM-1,beta-lactamase_2500,P62593,0.287943,NO,249,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.312,,,,0.256,S,B,0.23,0.04,30.841,30.841,72.73,HOO,-1.81367,0.361275,0.00220169,0.287943 kka2_1:1_L259N,kka2_1:1_259,Kka2,kka2_1:1,P00552,0.288019,NO,259,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.088,-4.082,2.994,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.520039,0.0206964,0.288019 kka2_1:1_S114D,kka2_1:1_114,Kka2,kka2_1:1,P00552,0.28803,NO,114,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.527,-2.691,0.164,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.520039,0.00705262,0.28803 WW_domain_P202H,WW_domain_202,Yap65,WW_domain,P46937,0.288059,NO,202,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.4,-4.514,3.114,5.64207,,,,,,17.28,17.28,78.57,AOB,-1.436,0.153962,0.00212903,0.288059 kka2_1:4_Y244K,kka2_1:4_244,Kka2,kka2_1:4,P00552,0.288068,NO,244,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-0.775,-3.71,2.935,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.168804,0.00453187,0.288068 kka2_1:4_V49N,kka2_1:4_49,Kka2,kka2_1:4,P00552,0.288123,NO,49,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.614,-4.184,2.57,,,E,B,0.44,-0.77,1.233,,64.39,HHB,-1.3,0.168804,0.00615685,0.288123 beta-lactamase_2500_A246N,beta-lactamase_2500_246,TEM-1,beta-lactamase_2500,P62593,0.28815,NO,246,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.121,-4.23,2.109,,0.01,E,B,0.46,-1.01,0.753,,73.78,HHH,-1.55633,0.361275,0.00569458,0.28815 kka2_1:1_C77P,kka2_1:1_77,Kka2,kka2_1:1,P00552,0.288182,NO,77,C,P,CP,Special,Special,5.07,6.3,1.23,169,121,115,-6,108.5,112.7,4.2,-1.477,-4.052,2.575,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.520039,0.00441216,0.288182 beta-lactamase_156_L284R,beta-lactamase_156_284,TEM-1,beta-lactamase_156,P62593,0.288187,NO,284,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.111618,0.0686156,0.288187 kka2_1:1_R143E,kka2_1:1_143,Kka2,kka2_1:1,P00552,0.288201,NO,143,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.525,-2.41,-0.115,,0.325,H,A,0.16,1.22,3.6,,65.53,ABH,-1.86833,0.520039,0.00662247,0.288201 beta-lactamase_2500_A34D,beta-lactamase_2500_34,TEM-1,beta-lactamase_2500,P62593,0.288279,NO,34,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.059,-3.876,1.817,,,H,A,0.46,-0.54,2.921,,73.78,AHA,-1.74967,0.361275,0.00407913,0.288279 gb1_A260R,gb1_260,gb1,gb1,P06654,0.288314,NO,260,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.486,-3.725,2.239,,,,,,,0.173,,9.6,HHP,-1.70967,0.177985,0.0055808,0.288314 gb1_G267S,gb1_267,gb1,gb1,P06654,0.288314,NO,267,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.676,-3.16,1.484,,,,,,,1.361,,12.72,AOA,-1.61833,0.177985,0.00264655,0.288314 gb1_G267Y,gb1_267,gb1,gb1,P06654,0.288314,NO,267,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.676,-3.678,2.002,,,,,,,1.361,,12.72,AOA,-1.61833,0.177985,0.00264655,0.288314 gb1_N261M,gb1_261,gb1,gb1,P06654,0.288314,NO,261,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-1.863,-4.438,2.575,,,,,,,1.191,,44.87,HPA,-2.16033,0.177985,0.0061875,0.288314 beta-lactamase_156_G249E,beta-lactamase_156_249,TEM-1,beta-lactamase_156,P62593,0.288329,NO,249,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.111618,0.00220169,0.288329 beta-lactamase_2500_V260W,beta-lactamase_2500_260,TEM-1,beta-lactamase_2500,P62593,0.28833,NO,260,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.361275,0.00471757,0.28833 kka2_1:1_D157R,kka2_1:1_157,Kka2,kka2_1:1,P00552,0.288333,NO,157,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.993,-3.936,2.943,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.520039,0.0042313,0.288333 beta-lactamase_156_S104L,beta-lactamase_156_104,TEM-1,beta-lactamase_156,P62593,0.28834,NO,104,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.015,-3.359,2.344,,0.04,,b,0.27,0.57,4.02,,63.29,HPO,-1.05267,0.111618,0.00218083,0.28834 kka2_1:8_L260S,kka2_1:8_260,Kka2,kka2_1:8,P00552,0.288342,NO,260,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.741,-3.639,2.898,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.100394,0.0233782,0.288342 kka2_1:8_L260S,kka2_1:8_260,Kka2,kka2_1:8,P00552,0.288342,NO,260,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.741,-3.639,2.898,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.100394,0.0233782,0.288342 kka2_1:1_E231I,kka2_1:1_231,Kka2,kka2_1:1,P00552,0.288379,NO,231,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.002,-3.963,1.961,,0.503,H,A,1.04,-0.23,25.629,25.629,63.26,AAH,-2.06267,0.520039,0.00732383,0.288379 kka2_1:1_E161H,kka2_1:1_161,Kka2,kka2_1:1,P00552,0.288382,NO,161,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.581,-4.674,3.093,,0.829,G,A,1.04,2.24,1.612,,92.05,AAB,-1.861,0.520039,0.00760103,0.288382 beta-lactamase_2500_S128T,beta-lactamase_2500_128,TEM-1,beta-lactamase_2500,P62593,0.288395,NO,128,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-0.84,-2.971,2.131,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.361275,0.00071483,0.288395 kka2_1:1_A14W,kka2_1:1_14,Kka2,kka2_1:1,P00552,0.288429,NO,14,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.837,-5.518,3.681,,0.728,G,A,0.46,0.7,1.17,,71.59,HHH,-1.82567,0.520039,0.00706614,0.288429 kka2_1:1_I115R,kka2_1:1_115,Kka2,kka2_1:1,P00552,0.288457,NO,115,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.606,-4.203,2.597,,0.105,H,A,0.48,-1.18,0.878,,65.53,PHH,-2.205,0.520039,0.00836567,0.288457 kka2_1:1_I228P,kka2_1:1_228,Kka2,kka2_1:1,P00552,0.288537,NO,228,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.142,-4.165,3.023,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.520039,0.00458834,0.288537 beta-lactamase_2500_I261Y,beta-lactamase_2500_261,TEM-1,beta-lactamase_2500,P62593,0.288558,NO,261,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.361275,0.0123091,0.288558 kka2_1:1_G151Y,kka2_1:1_151,Kka2,kka2_1:1,P00552,0.288565,NO,151,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.873,-4.442,3.569,,0.678,T,l,0.29,1.36,0.226,,49.62,HOH,-1.11433,0.520039,0.00339918,0.288565 beta-lactamase_39_F64N,beta-lactamase_39_64,TEM-1,beta-lactamase_39,P62593,0.288671,NO,64,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-0.841,-4.123,3.282,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.0495842,0.000947691,0.288671 kka2_1:1_D261K,kka2_1:1_261,Kka2,kka2_1:1,P00552,0.288723,NO,261,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.708,-3.485,2.777,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.520039,0.0224846,0.288723 beta-lactamase_2500_M184Q,beta-lactamase_2500_184,TEM-1,beta-lactamase_2500,P62593,0.288755,NO,184,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.593,-3.011,1.418,,,H,A,0.55,-0.87,2.893,,62.94,HHH,-1.41,0.361275,0.00356019,0.288755 kka2_1:1_G181L,kka2_1:1_181,Kka2,kka2_1:1,P00552,0.288762,NO,181,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-2.698,-3.595,0.897,,0.379,S,B,0.75,0.78,15.356,15.356,71.59,AOA,-2.21,0.520039,0.00728319,0.288762 beta-lactamase_625_L47N,beta-lactamase_625_47,TEM-1,beta-lactamase_625,P62593,0.288832,NO,47,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.876,-3.972,2.096,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.213352,0.00439844,0.288832 kka2_1:1_R122C,kka2_1:1_122,Kka2,kka2_1:1,P00552,0.288842,NO,122,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.175,-5.179,3.004,,0.487,H,A,1.2,0.26,1.356,,71.59,BBH,-1.53833,0.520039,0.00736512,0.288842 kka2_1:1_F264G,kka2_1:1_264,Kka2,kka2_1:1,P00552,0.288864,NO,264,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.02,-3.702,2.682,,0.296,.,?,0.58,0.02,2.303,,71.59,HHNA,-0.9655,0.520039,,0.288864 kka2_1:4_V36S,kka2_1:4_36,Kka2,kka2_1:4,P00552,0.288873,NO,36,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-0.898,-3.684,2.786,,0.292,E,B,0.44,0.21,0.278,,52.27,HHH,-1.484,0.168804,0.00245633,0.288873 kka2_1:4_L260D,kka2_1:4_260,Kka2,kka2_1:4,P00552,0.288916,NO,260,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.741,-4.172,3.431,,0.022,H,A,0.55,-0.52,,,,HHA,-0.845667,0.168804,0.0233782,0.288916 kka2_1:8_E231P,kka2_1:8_231,Kka2,kka2_1:8,P00552,0.288916,NO,231,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.002,-3.957,1.955,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.100394,0.00732383,0.288916 kka2_1:8_E231P,kka2_1:8_231,Kka2,kka2_1:8,P00552,0.288916,NO,231,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.002,-3.957,1.955,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.100394,0.00732383,0.288916 beta-lactamase_0_I171C,beta-lactamase_0_171,TEM-1,beta-lactamase_0,P62593,0.288918,NO,171,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-2.431,-4.938,2.507,,0.361,,B,0.48,0.53,16.954,16.954,77.62,HHO,-1.55533,0.0500837,0.00623355,0.288918 Pab1_I137R,Pab1_137,Pab1,Pab1,P04147,0.288923,NO,137,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.212,-3.975,2.763,,0.068,,B,0.77,0.35,,,,AHA,-1.314,0.175299,0.000342224,0.288923 beta-lactamase_E277P,beta-lactamase_277,TEM-1,beta-lactamase,P62593,0.288926,NO,277,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.869,-3.912,2.043,5.51786,0.545,H,A,0.52,-0.01,2.022,,77.62,HAH,-1.45367,0.221079,0.0169305,0.288926 kka2_1:4_I115Y,kka2_1:4_115,Kka2,kka2_1:4,P00552,0.288937,NO,115,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.606,-4.097,2.491,,0.105,H,A,1.52,-1.18,9.996,9.996,65.53,PHH,-2.205,0.168804,0.00836567,0.288937 kka2_1:4_G210D,kka2_1:4_210,Kka2,kka2_1:4,P00552,0.289011,NO,210,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.095,-3.632,2.537,,0.103,T,A,0.29,-0.62,0.271,,50,OOB,-0.966667,0.168804,0.00598378,0.289011 kka2_1:8_R211P,kka2_1:8_211,Kka2,kka2_1:8,P00552,0.289059,NO,211,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-0.899,-3.968,3.069,,0.12,T,a,0.16,-0.39,0.615,,49.62,OBH,-0.966,0.100394,0.00204888,0.289059 kka2_1:8_R211P,kka2_1:8_211,Kka2,kka2_1:8,P00552,0.289059,NO,211,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-0.899,-3.968,3.069,,0.12,T,a,0.16,-0.39,0.615,,49.62,OBH,-0.966,0.100394,0.00204888,0.289059 kka2_1:1_A41P,kka2_1:1_41,Kka2,kka2_1:1,P00552,0.289083,NO,41,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.879,-2.834,0.955,,0.184,.,B,0.46,-0.96,18.207,18.207,64.39,PHP,-2.477,0.520039,0.00543332,0.289083 kka2_1:2_V36N,kka2_1:2_36,Kka2,kka2_1:2,P00552,0.289134,NO,36,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-0.898,-4.196,3.298,,0.292,E,B,1.48,0.21,1.064,,52.27,HHH,-1.484,0.295029,0.00245633,0.289134 kka2_1:2_V36P,kka2_1:2_36,Kka2,kka2_1:2,P00552,0.289176,NO,36,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-0.898,-3.99,3.092,,0.292,E,B,1.48,0.21,1.064,,52.27,HHH,-1.484,0.295029,0.00245633,0.289176 Pab1_G169W,Pab1_169,Pab1,Pab1,P04147,0.289193,NO,169,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.809,-4.915,4.106,,,E,b,0.35,0.03,,,,HOH,-1.11567,0.175299,0.000302434,0.289193 beta-lactamase_2500_T263W,beta-lactamase_2500_263,TEM-1,beta-lactamase_2500,P62593,0.289208,NO,263,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.361275,0.0110582,0.289208 beta-lactamase_2500_Y95E,beta-lactamase_2500_95,TEM-1,beta-lactamase_2500,P62593,0.289266,NO,95,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-1.715,-3.911,2.196,,0.122,,b,0.21,-0.37,2.914,,77.62,BHP,-2.16167,0.361275,0.00479449,0.289266 kka2_1:1_F206P,kka2_1:1_206,Kka2,kka2_1:1,P00552,0.289393,NO,206,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.349,-4.311,2.962,,0.006,E,B,0.58,-1.21,0.978,,63.64,OHH,-1.04,0.520039,0.00936868,0.289393 kka2_1:4_F264N,kka2_1:4_264,Kka2,kka2_1:4,P00552,0.289408,NO,264,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.02,-4.176,3.156,,0.296,,?,1.62,0.02,1.93,,71.59,HHO,-0.9655,0.168804,,0.289408 beta-lactamase_2500_L135N,beta-lactamase_2500_135,TEM-1,beta-lactamase_2500,P62593,0.289427,NO,135,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.002,-4.152,3.15,,0.117,H,A,0.55,-0.58,0.795,,43.71,PHH,-1.03767,0.361275,0.00244423,0.289427 kka2_1:1_A255H,kka2_1:1_255,Kka2,kka2_1:1,P00552,0.28958,NO,255,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.715,-3.488,1.773,,0.466,H,A,0.46,-0.52,0.946,,65.53,HHH,-1.71267,0.520039,0.0126809,0.28958 kka2_1:1_S114H,kka2_1:1_114,Kka2,kka2_1:1,P00552,0.289589,NO,114,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.527,-3.031,0.504,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.520039,0.00705262,0.289589 beta-lactamase_156_G43I,beta-lactamase_156_43,TEM-1,beta-lactamase_156,P62593,0.289614,NO,43,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.62,-4.235,3.615,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.111618,0.00120151,0.289614 beta-lactamase_625_T179L,beta-lactamase_625_179,TEM-1,beta-lactamase_625,P62593,0.289647,NO,179,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.085,-3.263,2.178,,,E,B,0.22,-1.38,0.367,,73.08,PPH,-1.557,0.213352,0.00226045,0.289647 kka2_1:2_D250W,kka2_1:2_250,Kka2,kka2_1:2,P00552,0.289736,NO,250,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.015,-5.585,4.57,,0.274,.,b,0.75,-0.46,3.796,,51.89,OAP,-1.83933,0.295029,0.0177103,0.289736 beta-lactamase_625_W288A,beta-lactamase_625_288,TEM-1,beta-lactamase_625,P62593,0.289777,NO,288,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,,,,,,,,,,,,,BHO,,0.213352,,0.289777 WW_domain_T182P,WW_domain_182,Yap65,WW_domain,P46937,0.289811,NO,182,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.149,-3.432,2.283,6.20597,,,,,,,,,BPP,-1.483,0.153962,0.00294574,0.289811 kka2_1:2_A237P,kka2_1:2_237,Kka2,kka2_1:2,P00552,0.289883,NO,237,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.12,-4.041,1.921,,0.068,H,A,0.46,-0.71,2.369,,92.05,HHA,-2.10433,0.295029,0.012257,0.289883 kka2_1:1_R44W,kka2_1:1_44,Kka2,kka2_1:1,P00552,0.289911,NO,44,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.062,-5.515,3.453,,0.487,S,B,1.2,-0.35,2.717,,71.59,OBO,-1.80767,0.520039,0.00745043,0.289911 beta-lactamase_T69N,beta-lactamase_69,TEM-1,beta-lactamase,P62593,0.289935,NO,69,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-0.973,-3.537,2.564,5.16042,,G,A,0.69,-1.24,0.505,,93.01,PPH,-1.01833,0.221079,0.00127498,0.289935 beta-lactamase_39_Y44R,beta-lactamase_39_44,TEM-1,beta-lactamase_39,P62593,0.289948,NO,44,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-2.547,-4.123,1.576,,,E,B,0.21,-0.45,2.683,,73.78,OHH,-1.86267,0.0495842,0.00426364,0.289948 kka2_1:2_L184D,kka2_1:2_184,Kka2,kka2_1:2,P00552,0.289963,NO,184,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.496,-4.1,2.604,,0.489,E,B,0.55,-0.06,14.044,14.044,63.26,AHH,-1.24833,0.295029,0.00518742,0.289963 beta-lactamase_2500_R59W,beta-lactamase_2500_59,TEM-1,beta-lactamase_2500,P62593,0.28999,NO,59,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.345,-5.421,4.076,,0.329,S,L,1.2,-0.09,3.719,,73.08,HBO,-2.24267,0.361275,0.00318082,0.28999 kka2_1:2_Y244P,kka2_1:2_244,Kka2,kka2_1:2,P00552,0.289991,NO,244,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-0.775,-4.133,3.358,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.295029,0.00453187,0.289991 kka2_1:1_P12G,kka2_1:1_12,Kka2,kka2_1:1,P00552,0.290018,NO,12,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.853,-3.308,2.455,,,.,B,0.52,1.25,0.261,,48.11,POH,-1.80767,0.520039,0.00500011,0.290018 kka2_1:4_L259W,kka2_1:4_259,Kka2,kka2_1:4,P00552,0.290021,NO,259,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.088,-5.209,4.121,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.168804,0.0206964,0.290021 kka2_1:2_G213Y,kka2_1:2_213,Kka2,kka2_1:2,P00552,0.290022,NO,213,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.596,-4.416,3.82,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.295029,0.00187654,0.290022 beta-lactamase_2500_N168K,beta-lactamase_2500_168,TEM-1,beta-lactamase_2500,P62593,0.29005,NO,168,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-1.029,-3.307,2.278,,0.113,G,A,0.61,-0.4,2.9,,44.41,HPA,-1.13233,0.361275,0.00288667,0.29005 kka2_1:4_C131T,kka2_1:4_131,Kka2,kka2_1:4,P00552,0.290064,NO,131,C,T,CT,Special,Polar,5.07,5.6,0.53,149,121,119,-2,108.5,116.1,7.6,-0.831,-3.45,2.619,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.168804,0.00170814,0.290064 beta-lactamase_M66N,beta-lactamase_66,TEM-1,beta-lactamase,P62593,0.290089,NO,66,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.362,-4.083,2.721,5.29561,0.013,,A,1.3,-0.7,1.319,,73.08,OHH,-1.49567,0.221079,0.00412876,0.290089 beta-lactamase_625_G243L,beta-lactamase_625_243,TEM-1,beta-lactamase_625,P62593,0.290093,NO,243,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.213352,0.00464034,0.290093 kka2_1:1_L212I,kka2_1:1_212,Kka2,kka2_1:1,P00552,0.290177,NO,212,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.904,-3.012,2.108,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.520039,0.0031426,0.290177 kka2_1:1_G201P,kka2_1:1_201,Kka2,kka2_1:1,P00552,0.290201,NO,201,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.56,-3.175,1.615,,0.149,T,l,0.29,-0.57,16.092,16.092,52.65,POB,-1.92233,0.520039,0.00820117,0.290201 kka2_1:8_A144R,kka2_1:8_144,Kka2,kka2_1:8,P00552,0.290203,NO,144,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.859,-3.85,2.991,,,H,A,1.04,0.21,1.118,,52.65,BHB,-1.72933,0.100394,0.00231095,0.290203 kka2_1:8_A144R,kka2_1:8_144,Kka2,kka2_1:8,P00552,0.290203,NO,144,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.859,-3.85,2.991,,,H,A,1.04,0.21,1.118,,52.65,BHB,-1.72933,0.100394,0.00231095,0.290203 kka2_1:2_T51E,kka2_1:2_51,Kka2,kka2_1:2,P00552,0.290245,NO,51,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.199,-3.693,1.494,,0.05,E,B,0.22,-0.05,13.165,13.165,63.64,BPA,-1.76767,0.295029,0.00628861,0.290245 beta-lactamase_156_T69Q,beta-lactamase_156_69,TEM-1,beta-lactamase_156,P62593,0.290256,NO,69,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-0.973,-3.935,2.962,,,G,A,0.22,-1.24,4.194,,93.01,PPH,-1.01833,0.111618,0.00127498,0.290256 kka2_1:1_D183N,kka2_1:1_183,Kka2,kka2_1:1,P00552,0.29027,NO,183,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.204,-2.35,1.146,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.520039,0.00426304,0.29027 beta-lactamase_I244Y,beta-lactamase_244,TEM-1,beta-lactamase,P62593,0.290311,NO,244,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.555,-4.031,2.476,5.35885,,E,B,0.01,-0.84,0.379,,77.62,HHH,-1.385,0.221079,0.00605379,0.290311 Ubiquitin_I13P,Ubiquitin_13,Uba1,Ubiquitin,P0CG48,0.290323,NO,13,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.554,-4.142,2.588,5.19411,0.038,E,B,,-0.2,,,,PHP,-1.48,0.205827,0.000716423,0.290323 Ubiquitin_L69G,Ubiquitin_69,Uba1,Ubiquitin,P0CG48,0.290323,NO,69,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.445,-3.687,2.242,4.75624,0.051,E,B,2.89,-0.94,7.106,,34.31,BHH,-1.72933,0.205827,0.000919136,0.290323 Ubiquitin_L8P,Ubiquitin_8,Uba1,Ubiquitin,P0CG48,0.290323,NO,8,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.723,-2.948,1.225,5.28016,0.664,T,A,0.08,-0.34,0.664,,29.05,PHP,-1.51567,0.205827,0.000726165,0.290323 Ubiquitin_Y59P,Ubiquitin_59,Uba1,Ubiquitin,P0CG48,0.290323,NO,59,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-1.307,-4.135,2.828,5.05599,0.072,G,A,0.43,-0.74,2.566,,24.53,AHP,-1.568,0.205827,0.000775084,0.290323 kka2_1:2_C31T,kka2_1:2_31,Kka2,kka2_1:2,P00552,0.290325,NO,31,C,T,CT,Special,Polar,5.07,5.6,0.53,149,121,119,-2,108.5,116.1,7.6,-2.246,-3.606,1.36,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.295029,0.00681582,0.290325 kka2_1:8_F264K,kka2_1:8_264,Kka2,kka2_1:8,P00552,0.290346,NO,264,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.02,-3.94,2.92,,0.296,,?,1.62,0.02,1.553,,71.59,HHO,-0.9655,0.100394,,0.290346 kka2_1:8_F264K,kka2_1:8_264,Kka2,kka2_1:8,P00552,0.290346,NO,264,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.02,-3.94,2.92,,0.296,,?,1.62,0.02,1.553,,71.59,HHO,-0.9655,0.100394,,0.290346 kka2_1:1_G213Y,kka2_1:1_213,Kka2,kka2_1:1,P00552,0.290379,NO,213,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.596,-4.416,3.82,,,E,b,0.29,-0.4,,,,HOH,-0.920333,0.520039,0.00187654,0.290379 kka2_1:1_F263W,kka2_1:1_263,Kka2,kka2_1:1,P00552,0.290404,NO,263,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-0.911,-4.558,3.647,,0.006,G,A,0.58,-0.12,2.284,,45.83,AHH,-0.92,0.520039,0.0172454,0.290404 kka2_1:4_A108W,kka2_1:4_108,Kka2,kka2_1:4,P00552,0.290466,NO,108,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.061,-5.601,3.54,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.168804,0.00751209,0.290466 beta-lactamase_E87P,beta-lactamase_87,TEM-1,beta-lactamase,P62593,0.290597,NO,87,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.421,-3.872,2.451,5.41929,0.048,,B,0.52,0.92,1.754,,64.69,PAP,-1.969,0.221079,0.00337888,0.290597 kka2_1:2_F240P,kka2_1:2_240,Kka2,kka2_1:2,P00552,0.290611,NO,240,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-0.911,-4.356,3.445,,,H,A,0.58,-1.21,0.373,,50.38,BHH,-1.67267,0.295029,0.00552543,0.290611 beta-lactamase_625_N134Y,beta-lactamase_625_134,TEM-1,beta-lactamase_625,P62593,0.290615,NO,134,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-0.879,-4.188,3.309,,0.138,H,A,0.61,-0.6,3.776,,53.15,HPH,-1.02233,0.213352,0.000644786,0.290615 kka2_1:4_G189F,kka2_1:4_189,Kka2,kka2_1:4,P00552,0.29063,NO,189,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.596,-4.32,3.724,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.168804,0.00253688,0.29063 beta-lactamase_156_A246Q,beta-lactamase_156_246,TEM-1,beta-lactamase_156,P62593,0.290633,NO,246,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.121,-4.263,2.142,,0.01,E,B,0.46,-1.01,1.959,,73.78,HHH,-1.55633,0.111618,0.00569458,0.290633 kka2_1:2_F264N,kka2_1:2_264,Kka2,kka2_1:2,P00552,0.290723,NO,264,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.02,-4.176,3.156,,0.296,.,?,0.58,0.02,2.303,,71.59,HHNA,-0.9655,0.295029,,0.290723 kka2_1:2_W15P,kka2_1:2_15,Kka2,kka2_1:2,P00552,0.290741,NO,15,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-1.392,-4.349,2.957,,0.01,G,A,0.47,0.15,2.586,,52.27,HHH,-2.10533,0.295029,0.00585505,0.290741 hsp90_S586Y,hsp90_586,hsp90,hsp90,P02829,0.290775,NO,586,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.764,-3.316,0,4.65438,,,B,0.93,0.15,,,,HPH,-3.157,0.368192,0.000222939,0.290775 kka2_1:1_A119T,kka2_1:1_119,Kka2,kka2_1:1,P00552,0.29081,NO,119,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.073,-3.309,2.236,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.520039,0.00441074,0.29081 beta-lactamase_625_P143D,beta-lactamase_625_143,TEM-1,beta-lactamase_625,P62593,0.29082,NO,143,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.967,-3.622,2.655,,0.075,H,A,0.52,-0.37,1.445,,66.78,OOB,-1.354,0.213352,0.00114551,0.29082 beta-lactamase_2500_I261A,beta-lactamase_2500_261,TEM-1,beta-lactamase_2500,P62593,0.290835,NO,261,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.361275,0.0123091,0.290835 kka2_1:8_D208S,kka2_1:8_208,Kka2,kka2_1:8,P00552,0.290853,NO,208,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.708,-3.189,2.481,,0.36,,l,0.29,-1.01,,,,HAO,-0.929667,0.100394,0.00212588,0.290853 kka2_1:8_D208S,kka2_1:8_208,Kka2,kka2_1:8,P00552,0.290853,NO,208,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.708,-3.189,2.481,,0.36,,l,0.29,-1.01,,,,HAO,-0.929667,0.100394,0.00212588,0.290853 kka2_1:4_H162M,kka2_1:4_162,Kka2,kka2_1:4,P00552,0.29087,NO,162,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-2.319,-4.675,2.356,,0.071,G,A,0.17,1.01,3.187,,64.39,ABP,-2.02067,0.168804,0.00616145,0.29087 kka2_1:4_V97H,kka2_1:4_97,Kka2,kka2_1:4,P00552,0.290886,NO,97,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.453,-5.043,3.59,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.168804,0.00737869,0.290886 beta-lactamase_T178E,beta-lactamase_178,TEM-1,beta-lactamase,P62593,0.290916,NO,178,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-0.791,-3.44,2.649,5.06452,0.029,E,B,0.3,-1.07,,,,APP,-0.947667,0.221079,0.000684366,0.290916 kka2_1:8_A78W,kka2_1:8_78,Kka2,kka2_1:8,P00552,0.290916,NO,78,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.744,-5.551,3.807,,0.078,,B,1.04,-0.53,1.251,,56.06,OHH,-1.863,0.100394,0.00457299,0.290916 kka2_1:8_A78W,kka2_1:8_78,Kka2,kka2_1:8,P00552,0.290916,NO,78,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.744,-5.551,3.807,,0.078,,B,1.04,-0.53,1.251,,56.06,OHH,-1.863,0.100394,0.00457299,0.290916 kka2_1:8_R217N,kka2_1:8_217,Kka2,kka2_1:8,P00552,0.290916,NO,217,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.158,-3.736,2.578,,0.252,T,A,0.16,-0.59,1.151,,52.27,ABH,-1.127,0.100394,0.0047191,0.290916 kka2_1:8_R217N,kka2_1:8_217,Kka2,kka2_1:8,P00552,0.290916,NO,217,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.158,-3.736,2.578,,0.252,T,A,0.16,-0.59,1.151,,52.27,ABH,-1.127,0.100394,0.0047191,0.290916 beta-lactamase_2500_D212R,beta-lactamase_2500_212,TEM-1,beta-lactamase_2500,P62593,0.290923,NO,212,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.624,-3.921,2.297,,0.037,,b,0.75,-0.58,12.482,,74.48,HAB,-1.77667,0.361275,0.00644302,0.290923 beta-lactamase_2500_S233Q,beta-lactamase_2500_233,TEM-1,beta-lactamase_2500,P62593,0.290956,NO,233,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.886,-3.939,2.053,,0.016,E,B,0.27,-1.01,2.851,,77.62,BPO,-1.17267,0.361275,0.00311415,0.290956 beta-lactamase_625_D129F,beta-lactamase_625_129,TEM-1,beta-lactamase_625,P62593,0.29096,NO,129,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.816,-4.318,3.502,,,,B,0.75,-0.69,0.171,,34.97,PAP,-0.818,0.213352,0.00109178,0.29096 kka2_1:1_L184E,kka2_1:1_184,Kka2,kka2_1:1,P00552,0.291033,NO,184,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.496,-3.868,2.372,,0.489,E,B,0.55,-0.06,19.127,19.127,63.26,AHH,-1.24833,0.520039,0.00518742,0.291033 kka2_1:1_E169H,kka2_1:1_169,Kka2,kka2_1:1,P00552,0.291081,NO,169,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.996,-4.724,2.728,,0.422,H,A,1.04,0.3,7.546,7.546,65.53,HAH,-1.755,0.520039,0.00730086,0.291081 kka2_1:1_A255N,kka2_1:1_255,Kka2,kka2_1:1,P00552,0.291102,NO,255,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.715,-3.829,2.114,,0.466,H,A,0.46,-0.52,0.946,,65.53,HHH,-1.71267,0.520039,0.0126809,0.291102 kka2_1:1_G189F,kka2_1:1_189,Kka2,kka2_1:1,P00552,0.29116,NO,189,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.596,-4.32,3.724,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.520039,0.00253688,0.29116 kka2_1:1_T72H,kka2_1:1_72,Kka2,kka2_1:1,P00552,0.291219,NO,72,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.38,-4.753,2.373,,0.784,H,A,0.22,0.29,10.43,10.43,65.53,HPP,-2.238,0.520039,0.00750756,0.291219 kka2_1:1_R211D,kka2_1:1_211,Kka2,kka2_1:1,P00552,0.29123,NO,211,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-0.899,-3.783,2.884,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.520039,0.00204888,0.29123 beta-lactamase_2500_L47H,beta-lactamase_2500_47,TEM-1,beta-lactamase_2500,P62593,0.291255,NO,47,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.876,-2.811,0.935,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.361275,0.00439844,0.291255 kka2_1:1_L170N,kka2_1:1_170,Kka2,kka2_1:1,P00552,0.291283,NO,170,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.28,-4.225,2.945,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.520039,0.00730791,0.291283 kka2_1:2_G210T,kka2_1:2_210,Kka2,kka2_1:2,P00552,0.291321,NO,210,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.095,-3.513,2.418,,0.103,T,A,0.29,-0.62,0.271,,50,OOB,-0.966667,0.295029,0.00598378,0.291321 beta-lactamase_2500_V42E,beta-lactamase_2500_42,TEM-1,beta-lactamase_2500,P62593,0.291329,NO,42,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.564,-3.88,2.316,,0.017,E,B,0.44,-0.51,1.86,,63.99,BHO,-1.042,0.361275,0.00404515,0.291329 beta-lactamase_625_L248S,beta-lactamase_625_248,TEM-1,beta-lactamase_625,P62593,0.291332,NO,248,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.213352,0.00428493,0.291332 beta-lactamase_156_L248P,beta-lactamase_156_248,TEM-1,beta-lactamase_156,P62593,0.291338,NO,248,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.111618,0.00428493,0.291338 kka2_1:1_R253I,kka2_1:1_253,Kka2,kka2_1:1,P00552,0.291374,NO,253,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.356,-4.056,2.7,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.520039,0.0144195,0.291374 kka2_1:2_V97N,kka2_1:2_97,Kka2,kka2_1:2,P00552,0.291414,NO,97,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.453,-4.261,2.808,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.295029,0.00737869,0.291414 kka2_1:2_D220V,kka2_1:2_220,Kka2,kka2_1:2,P00552,0.291422,NO,220,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.787,-2.698,1.911,,,H,A,0.75,-1.14,0.745,,46.59,PAH,-1.152,0.295029,0.00158066,0.291422 kka2_1:4_L232Q,kka2_1:4_232,Kka2,kka2_1:4,P00552,0.291537,NO,232,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.514,-4.349,2.835,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.168804,0.00800103,0.291537 kka2_1:1_P98C,kka2_1:1_98,Kka2,kka2_1:1,P00552,0.291571,NO,98,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.526,-5.171,3.645,,0.391,S,B,0.52,-0.65,1.521,,63.26,HOO,-1.19167,0.520039,0.00622754,0.291571 kka2_1:1_G164P,kka2_1:1_164,Kka2,kka2_1:1,P00552,0.291581,NO,164,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.869,-3.944,3.075,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.520039,0.00442091,0.291581 beta-lactamase_625_L248E,beta-lactamase_625_248,TEM-1,beta-lactamase_625,P62593,0.291589,NO,248,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.213352,0.00428493,0.291589 kka2_1:1_F203E,kka2_1:1_203,Kka2,kka2_1:1,P00552,0.291626,NO,203,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-0.911,-3.952,3.041,,0.26,E,B,0.58,-0.92,7.323,,63.64,BHP,-1.34167,0.520039,0.00318738,0.291626 kka2_1:8_I221H,kka2_1:8_221,Kka2,kka2_1:8,P00552,0.291627,NO,221,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.739,-5.027,3.288,,,H,A,1.52,-1.15,1.599,,71.59,AHH,-1.08367,0.100394,0.00945908,0.291627 kka2_1:8_I221H,kka2_1:8_221,Kka2,kka2_1:8,P00552,0.291627,NO,221,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.739,-5.027,3.288,,,H,A,1.52,-1.15,1.599,,71.59,AHH,-1.08367,0.100394,0.00945908,0.291627 kka2_1:1_L47S,kka2_1:1_47,Kka2,kka2_1:1,P00552,0.291644,NO,47,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.265,-3.626,2.361,,0.139,E,B,0.55,-0.86,14.593,14.593,63.26,HHH,-1.77933,0.520039,0.00509386,0.291644 beta-lactamase_625_N274F,beta-lactamase_625_274,TEM-1,beta-lactamase_625,P62593,0.291687,NO,274,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.213352,0.0110418,0.291687 kka2_1:2_G201Y,kka2_1:2_201,Kka2,kka2_1:2,P00552,0.291753,NO,201,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.56,-4.462,2.902,,0.149,T,l,0.29,-0.57,16.092,16.092,52.65,POB,-1.92233,0.295029,0.00820117,0.291753 E1_Ubiquitin_G75K,E1_Ubiquitin_75,Uba1,E1_Ubiquitin,P0CG63,0.291777,NO,75,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.999,-3.248,2.249,,0.552,T,A,0.75,0.9,4.369,,83.73,BOO,-1.1,0.18783,0.00153276,0.291777 beta-lactamase_2500_T69L,beta-lactamase_2500_69,TEM-1,beta-lactamase_2500,P62593,0.291855,NO,69,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-0.973,-3.213,2.24,,,G,A,0.22,-1.24,2.05,,93.01,PPH,-1.01833,0.361275,0.00127498,0.291855 kka2_1:2_L170T,kka2_1:2_170,Kka2,kka2_1:2,P00552,0.291869,NO,170,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.28,-3.474,2.194,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.295029,0.00730791,0.291869 kka2_1:1_A166F,kka2_1:1_166,Kka2,kka2_1:1,P00552,0.291908,NO,166,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.407,-4.424,2.017,,0.534,.,B,0.46,1.03,1.147,,71.59,HHO,-2.421,0.520039,0.00799912,0.291908 beta-lactamase_625_S241M,beta-lactamase_625_241,TEM-1,beta-lactamase_625,P62593,0.291976,NO,241,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.213352,0.00452736,0.291976 beta-lactamase_2500_I280K,beta-lactamase_2500_280,TEM-1,beta-lactamase_2500,P62593,0.292008,NO,280,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.361275,0.0530888,0.292008 beta-lactamase_I93D,beta-lactamase_93,TEM-1,beta-lactamase,P62593,0.292039,NO,93,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.401,-4.003,2.602,5.74695,0.128,E,B,0.77,0.44,1.757,,67.83,BHB,-1.873,0.221079,0.00527066,0.292039 kka2_1:1_C209W,kka2_1:1_209,Kka2,kka2_1:1,P00552,0.292054,NO,209,C,W,CW,Special,Hydrophobic,5.07,5.89,0.82,215,121,204,83,108.5,227.8,119.3,-0.906,-5.149,4.243,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.520039,0.00260862,0.292054 kka2_1:2_R253V,kka2_1:2_253,Kka2,kka2_1:2,P00552,0.292092,NO,253,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.356,-3.689,2.333,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.295029,0.0144195,0.292092 kka2_1:1_R258E,kka2_1:1_258,Kka2,kka2_1:1,P00552,0.292094,NO,258,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.626,-2.838,1.212,,0.316,H,A,1.2,-0.85,7.485,7.485,53.03,HBH,-1.25933,0.520039,0.00983174,0.292094 beta-lactamase_D155S,beta-lactamase_155,TEM-1,beta-lactamase,P62593,0.292148,NO,155,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.889,-3.185,2.296,4.92265,0.049,,B,0.45,-0.9,3.208,,64.69,OAB,-1.62267,0.221079,0.00135315,0.292148 kka2_1:1_F203T,kka2_1:1_203,Kka2,kka2_1:1,P00552,0.292189,NO,203,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-0.911,-3.673,2.762,,0.26,E,B,0.58,-0.92,7.323,,63.64,BHP,-1.34167,0.520039,0.00318738,0.292189 kka2_1:8_L170K,kka2_1:8_170,Kka2,kka2_1:8,P00552,0.292195,NO,170,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.28,-3.796,2.516,,0.029,H,A,1.59,0.11,1.453,,62.5,AHH,-1.534,0.100394,0.00730791,0.292195 kka2_1:8_L170K,kka2_1:8_170,Kka2,kka2_1:8,P00552,0.292195,NO,170,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.28,-3.796,2.516,,0.029,H,A,1.59,0.11,1.453,,62.5,AHH,-1.534,0.100394,0.00730791,0.292195 kka2_1:1_G201E,kka2_1:1_201,Kka2,kka2_1:1,P00552,0.292208,NO,201,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.56,-2.596,1.036,,0.149,T,l,0.29,-0.57,16.092,16.092,52.65,POB,-1.92233,0.520039,0.00820117,0.292208 kka2_1:1_G201K,kka2_1:1_201,Kka2,kka2_1:1,P00552,0.292208,NO,201,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.56,-2.796,1.236,,0.149,T,l,0.29,-0.57,16.092,16.092,52.65,POB,-1.92233,0.520039,0.00820117,0.292208 beta-lactamase_156_T179P,beta-lactamase_156_179,TEM-1,beta-lactamase_156,P62593,0.292221,NO,179,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.085,-3.739,2.654,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.111618,0.00226045,0.292221 beta-lactamase_156_E35W,beta-lactamase_156_35,TEM-1,beta-lactamase_156,P62593,0.292258,NO,35,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-0.869,-5.371,4.502,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.111618,0.00174441,0.292258 kka2_1:4_H188A,kka2_1:4_188,Kka2,kka2_1:4,P00552,0.29231,NO,188,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-0.913,-3.329,2.416,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.168804,0.00273139,0.29231 kka2_1:2_I141N,kka2_1:2_141,Kka2,kka2_1:2,P00552,0.292364,NO,141,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.495,-4.275,2.78,,0.068,H,A,0.48,-0.01,0.819,,92.05,BHA,-1.689,0.295029,0.00744745,0.292364 beta-lactamase_156_L248H,beta-lactamase_156_248,TEM-1,beta-lactamase_156,P62593,0.29239,NO,248,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.111618,0.00428493,0.29239 kka2_1:1_A9N,kka2_1:1_9,Kka2,kka2_1:1,P00552,0.292501,NO,9,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.079,-2.623,0.544,,,,,,,0.383,,71.59,BHO,-2.253,0.520039,0.00273264,0.292501 beta-lactamase_L150E,beta-lactamase_150,TEM-1,beta-lactamase,P62593,0.292516,NO,150,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.326,-3.822,2.496,5.15566,,H,A,1.75,-0.2,1.615,,62.94,HHB,-1.86167,0.221079,0.00463171,0.292516 kka2_1:1_R258D,kka2_1:1_258,Kka2,kka2_1:1,P00552,0.292524,NO,258,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.626,-3.765,2.139,,0.316,H,A,1.2,-0.85,7.485,7.485,53.03,HBH,-1.25933,0.520039,0.00983174,0.292524 kka2_1:1_E96P,kka2_1:1_96,Kka2,kka2_1:1,P00552,0.292535,NO,96,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.573,-3.855,1.282,,0.476,,B,1.52,-0.65,1.254,,71.59,OAH,-2.143,0.520039,0.00369441,0.292535 kka2_1:1_L7N,kka2_1:1_7,Kka2,kka2_1:1,P00552,0.292589,NO,7,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.926,-3.49,1.564,,,,,,,18.934,18.934,71.59,OHB,-2.12333,0.520039,0.00269456,0.292589 kka2_1:2_L92H,kka2_1:2_92,Kka2,kka2_1:2,P00552,0.292619,NO,92,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.893,-4.966,4.073,,0.007,E,B,1.59,-0.19,1.447,,63.26,HHH,-0.962,0.295029,0.00307177,0.292619 kka2_1:4_K50D,kka2_1:4_50,Kka2,kka2_1:4,P00552,0.292628,NO,50,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-0.833,-3.541,2.708,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.168804,0.00138626,0.292628 beta-lactamase_156_I280H,beta-lactamase_156_280,TEM-1,beta-lactamase_156,P62593,0.292635,NO,280,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.111618,0.0530888,0.292635 beta-lactamase_T178F,beta-lactamase_178,TEM-1,beta-lactamase,P62593,0.292685,NO,178,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-0.791,-4.067,3.276,5.06452,0.029,E,B,0.3,-1.07,,,,APP,-0.947667,0.221079,0.000684366,0.292685 kka2_1:2_F256K,kka2_1:2_256,Kka2,kka2_1:2,P00552,0.292715,NO,256,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.49,-3.87,2.38,,,H,A,0.58,-0.78,1.653,,53.03,HHH,-1.423,0.295029,0.0132841,0.292715 beta-lactamase_2500_L49D,beta-lactamase_2500_49,TEM-1,beta-lactamase_2500,P62593,0.292737,NO,49,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.897,-3.778,1.881,,0.131,T,A,0.55,0.04,6.681,,64.69,AHP,-1.99233,0.361275,0.00401477,0.292737 kka2_1:8_F263R,kka2_1:8_263,Kka2,kka2_1:8,P00552,0.292762,NO,263,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-0.911,-4.185,3.274,,0.006,G,A,1.62,-0.12,0.928,,45.83,AHH,-0.92,0.100394,0.0172454,0.292762 kka2_1:8_F263R,kka2_1:8_263,Kka2,kka2_1:8,P00552,0.292762,NO,263,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-0.911,-4.185,3.274,,0.006,G,A,1.62,-0.12,0.928,,45.83,AHH,-0.92,0.100394,0.0172454,0.292762 beta-lactamase_2500_R273E,beta-lactamase_2500_273,TEM-1,beta-lactamase_2500,P62593,0.292791,NO,273,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.314,-2.209,-0.105,,0.564,H,A,1.2,1.57,19.943,19.943,73.78,ABP,-1.841,0.361275,0.0077952,0.292791 beta-lactamase_625_S80P,beta-lactamase_625_80,TEM-1,beta-lactamase_625,P62593,0.292821,NO,80,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.029,-3.939,1.91,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.213352,0.00565569,0.292821 kka2_1:2_G245N,kka2_1:2_245,Kka2,kka2_1:2,P00552,0.292855,NO,245,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.812,-2.694,1.882,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.295029,0.00683899,0.292855 beta-lactamase_156_V260Q,beta-lactamase_156_260,TEM-1,beta-lactamase_156,P62593,0.292864,NO,260,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.111618,0.00471757,0.292864 kka2_1:4_C192L,kka2_1:4_192,Kka2,kka2_1:4,P00552,0.292881,NO,192,C,L,CL,Special,Hydrophobic,5.07,9.7088,4.6388,198,121,131,10,108.5,166.7,58.2,-1.067,-3.26,2.193,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.168804,0.00485428,0.292881 kka2_1:4_D62K,kka2_1:4_62,Kka2,kka2_1:4,P00552,0.292904,NO,62,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.591,-3.652,2.061,,0.262,H,A,0.29,0.08,14.756,14.756,64.39,PAA,-1.77833,0.168804,0.00744243,0.292904 kka2_1:1_A119L,kka2_1:1_119,Kka2,kka2_1:1,P00552,0.292922,NO,119,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.073,-3.266,2.193,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.520039,0.00441074,0.292922 kka2_1:1_E182I,kka2_1:1_182,Kka2,kka2_1:1,P00552,0.292993,NO,182,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.516,-4.087,2.571,,0.326,,B,1.52,0.75,14.547,14.547,65.53,OAA,-1.806,0.520039,0.00641548,0.292993 kka2_1:8_D220W,kka2_1:8_220,Kka2,kka2_1:8,P00552,0.292998,NO,220,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.787,-5.574,4.787,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.100394,0.00158066,0.292998 kka2_1:8_D220W,kka2_1:8_220,Kka2,kka2_1:8,P00552,0.292998,NO,220,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.787,-5.574,4.787,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.100394,0.00158066,0.292998 Pab1_L142W,Pab1_142,Pab1,Pab1,P04147,0.293035,NO,142,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.039,-4.915,3.876,,0.007,H,A,0.84,-0.65,,,,HHH,-1.487,0.175299,0.000335477,0.293035 kka2_1:8_F206K,kka2_1:8_206,Kka2,kka2_1:8,P00552,0.293045,NO,206,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.349,-3.906,2.557,,0.006,E,B,1.62,-1.21,1.052,,63.64,OHH,-1.04,0.100394,0.00936868,0.293045 kka2_1:8_F206K,kka2_1:8_206,Kka2,kka2_1:8,P00552,0.293045,NO,206,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.349,-3.906,2.557,,0.006,E,B,1.62,-1.21,1.052,,63.64,OHH,-1.04,0.100394,0.00936868,0.293045 kka2_1:1_G245P,kka2_1:1_245,Kka2,kka2_1:1,P00552,0.293052,NO,245,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.812,-3.931,3.119,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.520039,0.00683899,0.293052 kka2_1:1_F48I,kka2_1:1_48,Kka2,kka2_1:1,P00552,0.293083,NO,48,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.453,-2.391,0.938,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.520039,0.00475422,0.293083 kka2_1:1_K112Y,kka2_1:1_112,Kka2,kka2_1:1,P00552,0.293083,NO,112,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-2.491,-4.32,1.829,,0.076,H,A,2.34,-1.37,23.433,23.433,56.06,ABH,-2.00133,0.520039,0.00645389,0.293083 kka2_1:1_G43W,kka2_1:1_43,Kka2,kka2_1:1,P00552,0.293094,NO,43,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.587,-5.439,3.852,,0.862,T,l,0.75,-0.67,2.247,,63.26,POB,-2.18533,0.520039,0.0071925,0.293094 kka2_1:4_F133C,kka2_1:4_133,Kka2,kka2_1:4,P00552,0.293105,NO,133,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-0.871,-4.914,4.043,,0.178,.,B,0.58,0.43,0.786,,42.42,OHA,-0.871667,0.168804,0.00182168,0.293105 beta-lactamase_G248R,beta-lactamase_248,TEM-1,beta-lactamase,P62593,0.293122,NO,248,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.794,-2.761,0.967,4.69798,,E,b,0.23,-0.43,1.782,,61.19,HOO,-1.52867,0.221079,0.00428493,0.293122 beta-lactamase_625_L284H,beta-lactamase_625_284,TEM-1,beta-lactamase_625,P62593,0.29316,NO,284,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.213352,0.0686156,0.29316 kka2_1:1_A119Q,kka2_1:1_119,Kka2,kka2_1:1,P00552,0.293167,NO,119,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.073,-4.017,2.944,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.520039,0.00441074,0.293167 kka2_1:1_R145A,kka2_1:1_145,Kka2,kka2_1:1,P00552,0.293204,NO,145,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.804,-2.368,0.564,,0.346,H,A,1.2,1.23,23.699,23.699,63.64,HBP,-1.88033,0.520039,0.00846663,0.293204 kka2_1:1_A129P,kka2_1:1_129,Kka2,kka2_1:1,P00552,0.293209,NO,129,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.656,-4.009,2.353,,0.845,G,A,0.46,0.72,19.686,19.686,92.05,OHP,-1.99,0.520039,0.00726862,0.293209 kka2_1:1_E111Y,kka2_1:1_111,Kka2,kka2_1:1,P00552,0.293209,NO,111,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.28,-4.387,2.107,,0.155,H,A,1.52,-1.14,15.716,15.716,65.53,HAB,-2.27833,0.520039,0.00746789,0.293209 kka2_1:4_D62I,kka2_1:4_62,Kka2,kka2_1:4,P00552,0.293308,NO,62,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.591,-4.096,2.505,,0.262,H,A,0.29,0.08,14.756,14.756,64.39,PAA,-1.77833,0.168804,0.00744243,0.293308 kka2_1:1_F256K,kka2_1:1_256,Kka2,kka2_1:1,P00552,0.293326,NO,256,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.49,-3.87,2.38,,,H,A,1.62,-0.78,2.354,,53.03,HHH,-1.423,0.520039,0.0132841,0.293326 kka2_1:1_F37I,kka2_1:1_37,Kka2,kka2_1:1,P00552,0.293342,NO,37,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.427,-3.594,2.167,,0.219,E,B,0.58,-0.25,18.64,18.64,64.39,HHB,-1.17733,0.520039,0.00586193,0.293342 kka2_1:4_V214H,kka2_1:4_214,Kka2,kka2_1:4,P00552,0.293367,NO,214,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.261,-5.011,3.75,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.168804,0.00692782,0.293367 kka2_1:2_R66Q,kka2_1:2_66,Kka2,kka2_1:2,P00552,0.293432,NO,66,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-0.922,-3.512,2.59,,0.103,H,A,1.2,-0.2,2.659,,46.21,HBH,-1.13567,0.295029,0.00161025,0.293432 beta-lactamase_625_D177C,beta-lactamase_625_177,TEM-1,beta-lactamase_625,P62593,0.293448,NO,177,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.967,-5.073,4.106,,0.006,T,L,0.75,-1.02,1.333,,64.69,BAP,-0.873667,0.213352,0.000864022,0.293448 kka2_1:1_I115W,kka2_1:1_115,Kka2,kka2_1:1,P00552,0.29345,NO,115,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.606,-5.354,3.748,,0.105,H,A,0.48,-1.18,0.878,,65.53,PHH,-2.205,0.520039,0.00836567,0.29345 beta-lactamase_G242Q,beta-lactamase_242,TEM-1,beta-lactamase,P62593,0.293454,NO,242,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.319,-3.963,2.644,4.68003,,E,B,0.87,-1.05,1.079,,50,BOH,-1.428,0.221079,0.00452879,0.293454 kka2_1:1_E160N,kka2_1:1_160,Kka2,kka2_1:1,P00552,0.293459,NO,160,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.683,-2.876,1.193,,0.989,G,A,1.04,2.28,0.273,,71.59,AAA,-1.36133,0.520039,0.00935762,0.293459 beta-lactamase_2500_P143F,beta-lactamase_2500_143,TEM-1,beta-lactamase_2500,P62593,0.293498,NO,143,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.967,-4.308,3.341,,0.075,H,A,0.52,-0.37,0.479,,66.78,OOB,-1.354,0.361275,0.00114551,0.293498 kka2_1:4_F203T,kka2_1:4_203,Kka2,kka2_1:4,P00552,0.29353,NO,203,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-0.911,-3.673,2.762,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.168804,0.00318738,0.29353 kka2_1:1_S104E,kka2_1:1_104,Kka2,kka2_1:1,P00552,0.293532,NO,104,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.436,-2.627,1.191,,0.536,T,A,0.27,-1.11,5.49,,63.64,HPP,-1.91433,0.520039,0.00555207,0.293532 beta-lactamase_2500_V29P,beta-lactamase_2500_29,TEM-1,beta-lactamase_2500,P62593,0.293542,NO,29,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-2.856,-3.853,0.997,,0.733,H,A,0.44,-0.78,1.931,,93.01,HHB,-2.24733,0.361275,0.00318969,0.293542 beta-lactamase_P65R,beta-lactamase_65,TEM-1,beta-lactamase,P62593,0.293551,NO,65,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.894,-3.951,3.057,5.59094,0.098,E,B,0.23,-0.62,0.623,,40.56,HOH,-1.03233,0.221079,0.00152776,0.293551 beta-lactamase_625_P65D,beta-lactamase_625_65,TEM-1,beta-lactamase_625,P62593,0.293554,NO,65,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.894,-3.578,2.684,,0.098,E,B,0.52,-0.62,0.3,,40.56,HOH,-1.03233,0.213352,0.00152776,0.293554 beta-lactamase_I229K,beta-lactamase_229,TEM-1,beta-lactamase,P62593,0.293566,NO,229,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.267,-3.862,2.595,5.0911,0.083,E,B,1,-0.76,1.114,,50,HHH,-1.58767,0.221079,0.00477249,0.293566 beta-lactamase_L146N,beta-lactamase_146,TEM-1,beta-lactamase,P62593,0.293593,NO,146,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.462,-4.208,2.746,5.62483,0.007,H,A,1.3,-0.56,1.953,,64.69,AHP,-1.656,0.221079,0.00474542,0.293593 kka2_1:1_G164E,kka2_1:1_164,Kka2,kka2_1:1,P00552,0.293621,NO,164,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.869,-3.557,2.688,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.520039,0.00442091,0.293621 kka2_1:4_W236K,kka2_1:4_236,Kka2,kka2_1:4,P00552,0.293746,NO,236,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-1.363,-3.959,2.596,,0.303,H,A,0.47,-0.76,2.277,,48.48,AHH,-1.81267,0.168804,0.0088796,0.293746 kka2_1:8_L94W,kka2_1:8_94,Kka2,kka2_1:8,P00552,0.293752,NO,94,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.618,-5.174,3.556,,0.058,E,B,1.59,-0.52,2.197,,56.06,HHO,-1.612,0.100394,0.00520888,0.293752 kka2_1:8_L94W,kka2_1:8_94,Kka2,kka2_1:8,P00552,0.293752,NO,94,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.618,-5.174,3.556,,0.058,E,B,1.59,-0.52,2.197,,56.06,HHO,-1.612,0.100394,0.00520888,0.293752 beta-lactamase_156_G142W,beta-lactamase_156_142,TEM-1,beta-lactamase_156,P62593,0.293769,NO,142,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.707,-5.146,4.439,,0.034,,p,0.29,-0.64,0.325,,64.69,OOO,-0.834,0.111618,0.00060149,0.293769 beta-lactamase_2500_L74G,beta-lactamase_2500_74,TEM-1,beta-lactamase_2500,P62593,0.293771,NO,74,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.296,-3.477,2.181,,,H,A,0.55,-0.91,0.746,,50,HHO,-1.34933,0.361275,0.00493255,0.293771 kka2_1:4_I196D,kka2_1:4_196,Kka2,kka2_1:4,P00552,0.293774,NO,196,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-2.115,-4.156,2.041,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.168804,0.0107273,0.293774 beta-lactamase_2500_P65T,beta-lactamase_2500_65,TEM-1,beta-lactamase_2500,P62593,0.293786,NO,65,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.894,-3.44,2.546,,0.098,E,B,0.52,-0.62,0.3,,40.56,HOH,-1.03233,0.361275,0.00152776,0.293786 beta-lactamase_2500_A185T,beta-lactamase_2500_185,TEM-1,beta-lactamase_2500,P62593,0.293791,NO,185,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.406,-2.128,0.722,,,H,A,0.46,-1.02,2.999,,65.03,HHP,-1.84033,0.361275,0.00467449,0.293791 kka2_1:4_F240L,kka2_1:4_240,Kka2,kka2_1:4,P00552,0.293814,NO,240,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-0.911,-2.161,1.25,,,H,A,0.58,-1.21,5.798,,50.38,BHH,-1.67267,0.168804,0.00552543,0.293814 kka2_1:2_D118F,kka2_1:2_118,Kka2,kka2_1:2,P00552,0.293831,NO,118,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.07,-4.414,2.344,,0.61,H,A,0.75,-0.05,2.237,,64.39,HAH,-1.32367,0.295029,0.0067852,0.293831 kka2_1:1_F240E,kka2_1:1_240,Kka2,kka2_1:1,P00552,0.29389,NO,240,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-0.911,-3.952,3.041,,,H,A,1.62,-1.21,5.798,,50.38,BHH,-1.67267,0.520039,0.00552543,0.29389 kka2_1:1_V36I,kka2_1:1_36,Kka2,kka2_1:1,P00552,0.293935,NO,36,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-0.898,-1.989,1.091,,0.292,E,B,0.44,0.21,0.278,,52.27,HHH,-1.484,0.520039,0.00245633,0.293935 kka2_1:4_A215L,kka2_1:4_215,Kka2,kka2_1:4,P00552,0.293981,NO,215,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.968,-3.296,2.328,,0.039,E,B,0.46,-0.59,0.754,,50.38,HHA,-1.00467,0.168804,0.00529129,0.293981 beta-lactamase_2500_L79W,beta-lactamase_2500_79,TEM-1,beta-lactamase_2500,P62593,0.29399,NO,79,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.842,-5.095,4.253,,0.007,H,A,0.55,-0.16,0.823,,50.35,HHP,-1.44333,0.361275,0.000947397,0.29399 Pab1_F168N,Pab1_168,Pab1,Pab1,P04147,0.293996,NO,168,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.269,-3.934,2.665,,,,,,,0.789,,56.33,OHO,-1.10033,0.175299,0.00064061,0.293996 kka2_1:1_A215H,kka2_1:1_215,Kka2,kka2_1:1,P00552,0.294009,NO,215,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.968,-4.735,3.767,,0.039,E,B,0.46,-0.59,0.754,,50.38,HHA,-1.00467,0.520039,0.00529129,0.294009 kka2_1:4_L92H,kka2_1:4_92,Kka2,kka2_1:4,P00552,0.29407,NO,92,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.893,-4.966,4.073,,0.007,E,B,0.55,-0.19,1.447,,63.26,HHH,-0.962,0.168804,0.00307177,0.29407 beta-lactamase_2500_I245G,beta-lactamase_2500_245,TEM-1,beta-lactamase_2500,P62593,0.29415,NO,245,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.361275,0.00391032,0.29415 kka2_1:1_R66T,kka2_1:1_66,Kka2,kka2_1:1,P00552,0.294218,NO,66,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-0.922,-3.484,2.562,,0.103,H,A,1.2,-0.2,2.659,,46.21,HBH,-1.13567,0.520039,0.00161025,0.294218 beta-lactamase_625_I229T,beta-lactamase_625_229,TEM-1,beta-lactamase_625,P62593,0.294272,NO,229,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.267,-2.621,1.354,,0.083,E,B,0.48,-0.76,1.69,,50,HHH,-1.58767,0.213352,0.00477249,0.294272 kka2_1:8_F203K,kka2_1:8_203,Kka2,kka2_1:8,P00552,0.294317,NO,203,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-0.911,-3.934,3.023,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.100394,0.00318738,0.294317 kka2_1:8_F203K,kka2_1:8_203,Kka2,kka2_1:8,P00552,0.294317,NO,203,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-0.911,-3.934,3.023,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.100394,0.00318738,0.294317 kka2_1:1_E17M,kka2_1:1_17,Kka2,kka2_1:1,P00552,0.294337,NO,17,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.154,-4.855,2.701,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.520039,0.00688738,0.294337 beta-lactamase_I229G,beta-lactamase_229,TEM-1,beta-lactamase,P62593,0.294342,NO,229,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.267,-3.782,2.515,5.0911,0.083,E,B,1,-0.76,1.114,,50,HHH,-1.58767,0.221079,0.00477249,0.294342 kka2_1:1_M148P,kka2_1:1_148,Kka2,kka2_1:1,P00552,0.294371,NO,148,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.847,-4.116,2.269,,0.268,H,A,1.59,0.71,4.618,,64.39,BHA,-1.65467,0.520039,0.00982664,0.294371 kka2_1:1_G205H,kka2_1:1_205,Kka2,kka2_1:1,P00552,0.294427,NO,205,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.596,-4.708,4.112,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.520039,0.00221855,0.294427 beta-lactamase_39_E56P,beta-lactamase_39_56,TEM-1,beta-lactamase_39,P62593,0.294443,NO,56,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.043,-3.731,1.688,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.0495842,0.00238534,0.294443 beta-lactamase_2500_L219T,beta-lactamase_2500_219,TEM-1,beta-lactamase_2500,P62593,0.29445,NO,219,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.313,-3.55,2.237,,,I,A,0.55,-0.51,35.994,35.994,74.48,HHB,-1.21533,0.361275,0.00664345,0.29445 beta-lactamase_2500_A40F,beta-lactamase_2500_40,TEM-1,beta-lactamase_2500,P62593,0.294464,NO,40,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.402,-4.227,2.825,,0.155,S,B,0.46,0.21,0.953,,73.78,OHB,-1.40267,0.361275,0.00490026,0.294464 Pab1_V198H,Pab1_198,Pab1,Pab1,P04147,0.294468,NO,198,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.113,-4.722,3.609,,0.008,E,B,0.61,0.91,,,,HHH,-1.32933,0.175299,0.000268557,0.294468 kka2_1:4_L94D,kka2_1:4_94,Kka2,kka2_1:4,P00552,0.294478,NO,94,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.618,-4.088,2.47,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.168804,0.00520888,0.294478 kka2_1:4_A222Q,kka2_1:4_222,Kka2,kka2_1:4,P00552,0.294504,NO,222,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.725,-3.928,3.203,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.168804,0.00207657,0.294504 beta-lactamase_2500_R220V,beta-lactamase_2500_220,TEM-1,beta-lactamase_2500,P62593,0.294523,NO,220,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-0.942,-3.675,2.733,,0.295,I,A,1.2,-0.76,2.175,,74.48,HBP,-1.33633,0.361275,0.00232421,0.294523 kka2_1:1_G213K,kka2_1:1_213,Kka2,kka2_1:1,P00552,0.294527,NO,213,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.596,-3.71,3.114,,,E,b,0.29,-0.4,,,,HOH,-0.920333,0.520039,0.00187654,0.294527 kka2_1:1_G213P,kka2_1:1_213,Kka2,kka2_1:1,P00552,0.294527,NO,213,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.596,-3.908,3.312,,,E,b,0.29,-0.4,,,,HOH,-0.920333,0.520039,0.00187654,0.294527 kka2_1:1_G74S,kka2_1:1_74,Kka2,kka2_1:1,P00552,0.294606,NO,74,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.18,-2.717,1.537,,0.621,T,l,0.75,0.2,15.356,15.356,64.39,POH,-1.91667,0.520039,0.00587035,0.294606 beta-lactamase_156_T179I,beta-lactamase_156_179,TEM-1,beta-lactamase_156,P62593,0.294646,NO,179,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.085,-3.69,2.605,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.111618,0.00226045,0.294646 kka2_1:1_V49Q,kka2_1:1_49,Kka2,kka2_1:1,P00552,0.294652,NO,49,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.614,-4.261,2.647,,,E,B,0.44,-0.77,3.665,3.665,64.39,HHB,-1.3,0.520039,0.00615685,0.294652 beta-lactamase_2500_S68C,beta-lactamase_2500_68,TEM-1,beta-lactamase_2500,P62593,0.29467,NO,68,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-0.913,-4.705,3.792,,0.064,G,A,0.27,-1.03,2.824,,64.69,HPP,-1.37233,0.361275,0.000800065,0.29467 kka2_1:1_I207H,kka2_1:1_207,Kka2,kka2_1:1,P00552,0.294807,NO,207,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.175,-5.02,3.845,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.520039,0.00611824,0.294807 kka2_1:1_A247M,kka2_1:1_247,Kka2,kka2_1:1,P00552,0.29487,NO,247,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.459,-3.49,1.031,,1.01,S,A,0.46,0.65,7.731,7.731,92.05,HHH,-2.197,0.520039,0.0102428,0.29487 kka2_1:1_A255P,kka2_1:1_255,Kka2,kka2_1:1,P00552,0.294884,NO,255,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.715,-3.184,1.469,,0.466,H,A,0.46,-0.52,0.946,,65.53,HHH,-1.71267,0.520039,0.0126809,0.294884 kka2_1:2_D208E,kka2_1:2_208,Kka2,kka2_1:2,P00552,0.294893,NO,208,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.708,-2.793,2.085,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.295029,0.00212588,0.294893 beta-lactamase_625_R220V,beta-lactamase_625_220,TEM-1,beta-lactamase_625,P62593,0.294937,NO,220,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-0.942,-3.675,2.733,,0.295,I,A,1.2,-0.76,5.086,,74.48,HBP,-1.33633,0.213352,0.00232421,0.294937 kka2_1:1_R258K,kka2_1:1_258,Kka2,kka2_1:1,P00552,0.294939,NO,258,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.626,-3.325,1.699,,0.316,H,A,1.2,-0.85,7.485,7.485,53.03,HBH,-1.25933,0.520039,0.00983174,0.294939 kka2_1:4_G213K,kka2_1:4_213,Kka2,kka2_1:4,P00552,0.294962,NO,213,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.596,-3.71,3.114,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.168804,0.00187654,0.294962 kka2_1:4_G213P,kka2_1:4_213,Kka2,kka2_1:4,P00552,0.294962,NO,213,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.596,-3.908,3.312,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.168804,0.00187654,0.294962 kka2_1:2_A229I,kka2_1:2_229,Kka2,kka2_1:2,P00552,0.294974,NO,229,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.739,-3.861,2.122,,0.32,H,A,0.46,-0.7,6.549,,63.64,HHA,-1.851,0.295029,0.00942138,0.294974 Pab1_F129R,Pab1_129,Pab1,Pab1,P04147,0.295,NO,129,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.269,-3.969,2.7,,0.219,E,B,0.03,-0.07,1.307,,73.83,HHH,-1.27533,0.175299,0.000625182,0.295 kka2_1:4_A215D,kka2_1:4_215,Kka2,kka2_1:4,P00552,0.295068,NO,215,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.968,-3.663,2.695,,0.039,E,B,0.46,-0.59,0.754,,50.38,HHA,-1.00467,0.168804,0.00529129,0.295068 kka2_1:4_A215H,kka2_1:4_215,Kka2,kka2_1:4,P00552,0.29507,NO,215,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.968,-4.735,3.767,,0.039,E,B,0.46,-0.59,0.754,,50.38,HHA,-1.00467,0.168804,0.00529129,0.29507 kka2_1:1_V46K,kka2_1:1_46,Kka2,kka2_1:1,P00552,0.295089,NO,46,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-2.62,-3.127,0.507,,0.192,.,B,0.44,-1.12,20.149,20.149,92.05,OHH,-1.88633,0.520039,0.00631301,0.295089 beta-lactamase_625_G240F,beta-lactamase_625_240,TEM-1,beta-lactamase_625,P62593,0.295135,NO,240,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.213352,0.00591201,0.295135 kka2_1:1_L260D,kka2_1:1_260,Kka2,kka2_1:1,P00552,0.295173,NO,260,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.741,-4.172,3.431,,0.022,H,A,0.55,-0.52,,,,HHA,-0.845667,0.520039,0.0233782,0.295173 beta-lactamase_39_I261E,beta-lactamase_39_261,TEM-1,beta-lactamase_39,P62593,0.295243,NO,261,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.0495842,0.0123091,0.295243 kka2_1:2_R258P,kka2_1:2_258,Kka2,kka2_1:2,P00552,0.295262,NO,258,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.626,-4.055,2.429,,0.316,H,A,1.2,-0.85,7.485,7.485,53.03,HBH,-1.25933,0.295029,0.00983174,0.295262 kka2_1:1_P194V,kka2_1:1_194,Kka2,kka2_1:1,P00552,0.29527,NO,194,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.846,-3.62,2.774,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.520039,0.00314194,0.29527 beta-lactamase_2500_D177Y,beta-lactamase_2500_177,TEM-1,beta-lactamase_2500,P62593,0.295296,NO,177,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.967,-4.413,3.446,,0.006,T,L,0.75,-1.02,4.131,,64.69,BAP,-0.873667,0.361275,0.000864022,0.295296 kka2_1:4_A117K,kka2_1:4_117,Kka2,kka2_1:4,P00552,0.295308,NO,117,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.828,-3.549,2.721,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.168804,0.00282984,0.295308 E1_Ubiquitin_R42D,E1_Ubiquitin_42,Uba1,E1_Ubiquitin,P0CG63,0.295314,NO,42,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.302,-3.504,2.202,,0.244,E,B,,-0.54,,,,PBH,-1.24667,0.18783,0.00224033,0.295314 kka2_1:2_D101F,kka2_1:2_101,Kka2,kka2_1:2,P00552,0.295399,NO,101,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.028,-4.345,3.317,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.295029,0.00423361,0.295399 beta-lactamase_156_A246Y,beta-lactamase_156_246,TEM-1,beta-lactamase_156,P62593,0.2954,NO,246,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.121,-4.018,1.897,,0.01,E,B,0.46,-1.01,1.959,,73.78,HHH,-1.55633,0.111618,0.00569458,0.2954 kka2_1:1_Q219E,kka2_1:1_219,Kka2,kka2_1:1,P00552,0.295409,NO,219,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-0.93,-2.854,1.924,,0.088,H,A,0.4,-0.85,1.917,,50,HPA,-1.05167,0.520039,0.00237913,0.295409 beta-lactamase_2500_S128K,beta-lactamase_2500_128,TEM-1,beta-lactamase_2500,P62593,0.295435,NO,128,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-0.84,-3.232,2.392,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.361275,0.00071483,0.295435 beta-lactamase_D83P,beta-lactamase_83,TEM-1,beta-lactamase,P62593,0.29544,NO,83,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.066,-3.748,2.682,5.40616,0.354,H,A,1.33,0.22,0.861,,48.95,HAH,-1.34733,0.221079,0.00205968,0.29544 kka2_1:2_L158K,kka2_1:2_158,Kka2,kka2_1:2,P00552,0.295477,NO,158,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.947,-3.896,1.949,,0.095,,B,1.59,0.77,7.588,,63.64,AHA,-1.25333,0.295029,0.00529068,0.295477 kka2_1:1_I115L,kka2_1:1_115,Kka2,kka2_1:1,P00552,0.295493,NO,115,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.606,-1.667,0.061,,0.105,H,A,0.48,-1.18,0.878,,65.53,PHH,-2.205,0.520039,0.00836567,0.295493 beta-lactamase_156_C121R,beta-lactamase_156_121,TEM-1,beta-lactamase_156,P62593,0.295495,NO,121,C,R,CR,Special,PositiveCharge,5.07,6.34148,1.27148,180,121,174,53,108.5,173.4,64.9,-0.953,-2.762,1.809,,,H,A,0.46,-0.81,1.136,,63.29,HOP,-1.46767,0.111618,0.000744322,0.295495 kka2_1:2_E169W,kka2_1:2_169,Kka2,kka2_1:2,P00552,0.295528,NO,169,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.996,-5.529,3.533,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.295029,0.00730086,0.295528 kka2_1:2_I221N,kka2_1:2_221,Kka2,kka2_1:2,P00552,0.295542,NO,221,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.739,-4.276,2.537,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.295029,0.00945908,0.295542 kka2_1:1_T73N,kka2_1:1_73,Kka2,kka2_1:1,P00552,0.295676,NO,73,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.51,-3.876,1.366,,0.309,H,A,0.22,0.35,4.126,,56.06,PPO,-2.02333,0.520039,0.00628605,0.295676 kka2_1:1_L170W,kka2_1:1_170,Kka2,kka2_1:1,P00552,0.295687,NO,170,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.28,-5.33,4.05,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.520039,0.00730791,0.295687 kka2_1:4_C192Y,kka2_1:4_192,Kka2,kka2_1:4,P00552,0.295711,NO,192,C,Y,CY,Special,Hydrophobic,5.07,5.66,0.59,194,121,181,60,108.5,193.6,85.1,-1.067,-2.934,1.867,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.168804,0.00485428,0.295711 beta-lactamase_156_V259H,beta-lactamase_156_259,TEM-1,beta-lactamase_156,P62593,0.295714,NO,259,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.111618,0.0070773,0.295714 kka2_1:4_F256K,kka2_1:4_256,Kka2,kka2_1:4,P00552,0.295716,NO,256,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.49,-3.87,2.38,,,H,A,0.58,-0.78,1.653,,53.03,HHH,-1.423,0.168804,0.0132841,0.295716 kka2_1:8_G189A,kka2_1:8_189,Kka2,kka2_1:8,P00552,0.295723,NO,189,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.596,-2.881,2.285,,0.034,S,l,0.75,-0.99,,,,BOA,-0.739,0.100394,0.00253688,0.295723 kka2_1:8_G189A,kka2_1:8_189,Kka2,kka2_1:8,P00552,0.295723,NO,189,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.596,-2.881,2.285,,0.034,S,l,0.75,-0.99,,,,BOA,-0.739,0.100394,0.00253688,0.295723 kka2_1:2_L94K,kka2_1:2_94,Kka2,kka2_1:2,P00552,0.295765,NO,94,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.618,-3.731,2.113,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.295029,0.00520888,0.295765 beta-lactamase_T178K,beta-lactamase_178,TEM-1,beta-lactamase,P62593,0.295808,NO,178,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-0.791,-3.457,2.666,5.06452,0.029,E,B,0.3,-1.07,,,,APP,-0.947667,0.221079,0.000684366,0.295808 beta-lactamase_T178D,beta-lactamase_178,TEM-1,beta-lactamase,P62593,0.295852,NO,178,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-0.791,-3.469,2.678,5.06452,0.029,E,B,0.3,-1.07,,,,APP,-0.947667,0.221079,0.000684366,0.295852 kka2_1:2_K112Y,kka2_1:2_112,Kka2,kka2_1:2,P00552,0.295948,NO,112,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-2.491,-4.32,1.829,,0.076,H,A,2.34,-1.37,23.433,23.433,56.06,ABH,-2.00133,0.295029,0.00645389,0.295948 kka2_1:2_V49W,kka2_1:2_49,Kka2,kka2_1:2,P00552,0.29596,NO,49,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.614,-5.38,3.766,,,E,B,0.44,-0.77,1.233,,64.39,HHB,-1.3,0.295029,0.00615685,0.29596 kka2_1:8_D190K,kka2_1:8_190,Kka2,kka2_1:8,P00552,0.296004,NO,190,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.708,-3.485,2.777,,0.213,S,b,0.29,-0.82,,,,OAH,-0.711667,0.100394,0.00247989,0.296004 kka2_1:8_D190K,kka2_1:8_190,Kka2,kka2_1:8,P00552,0.296004,NO,190,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.708,-3.485,2.777,,0.213,S,b,0.29,-0.82,,,,OAH,-0.711667,0.100394,0.00247989,0.296004 beta-lactamase_T131K,beta-lactamase_131,TEM-1,beta-lactamase,P62593,0.296027,NO,131,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.328,-3.481,2.153,5.0548,,H,A,0.53,-0.69,3.306,,67.48,PPH,-1.00867,0.221079,0.00345886,0.296027 kka2_1:1_D101R,kka2_1:1_101,Kka2,kka2_1:1,P00552,0.296038,NO,101,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.028,-3.968,2.94,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.520039,0.00423361,0.296038 kka2_1:2_R217Y,kka2_1:2_217,Kka2,kka2_1:2,P00552,0.296103,NO,217,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.158,-4.252,3.094,,0.252,T,A,1.2,-0.59,0.381,,52.27,ABH,-1.127,0.295029,0.0047191,0.296103 kka2_1:1_E199S,kka2_1:1_199,Kka2,kka2_1:1,P00552,0.296116,NO,199,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.234,-2.389,0.155,,0.508,E,B,1.04,-0.43,3.012,,65.53,HAP,-2.133,0.520039,0.00854122,0.296116 beta-lactamase_156_T158Y,beta-lactamase_156_158,TEM-1,beta-lactamase_156,P62593,0.296151,NO,158,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.116,-4.258,3.142,,0.036,,B,0.22,-0.85,3.771,,69.58,HPB,-1.269,0.111618,0.00341825,0.296151 beta-lactamase_39_L248K,beta-lactamase_39_248,TEM-1,beta-lactamase_39,P62593,0.296207,NO,248,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.0495842,0.00428493,0.296207 kka2_1:2_L39W,kka2_1:2_39,Kka2,kka2_1:2,P00552,0.296284,NO,39,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.223,-5.273,4.05,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.295029,0.00493618,0.296284 kka2_1:4_G201E,kka2_1:4_201,Kka2,kka2_1:4,P00552,0.2963,NO,201,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.56,-2.596,1.036,,0.149,T,l,0.29,-0.57,0.284,,52.65,POB,-1.92233,0.168804,0.00820117,0.2963 kka2_1:1_F256M,kka2_1:1_256,Kka2,kka2_1:1,P00552,0.296341,NO,256,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.49,-4.553,3.063,,,H,A,1.62,-0.78,2.354,,53.03,HHH,-1.423,0.520039,0.0132841,0.296341 kka2_1:4_I115Q,kka2_1:4_115,Kka2,kka2_1:4,P00552,0.296357,NO,115,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.606,-4.312,2.706,,0.105,H,A,1.52,-1.18,9.996,9.996,65.53,PHH,-2.205,0.168804,0.00836567,0.296357 kka2_1:2_R258A,kka2_1:2_258,Kka2,kka2_1:2,P00552,0.296379,NO,258,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.626,-3.206,1.58,,0.316,H,A,1.2,-0.85,7.485,7.485,53.03,HBH,-1.25933,0.295029,0.00983174,0.296379 beta-lactamase_625_M115P,beta-lactamase_625_115,TEM-1,beta-lactamase_625,P62593,0.296382,NO,115,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.389,-4.034,2.645,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.213352,0.0034337,0.296382 beta-lactamase_2500_A34N,beta-lactamase_2500_34,TEM-1,beta-lactamase_2500,P62593,0.296386,NO,34,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.059,-3.965,1.906,,,H,A,0.46,-0.54,2.921,,73.78,AHA,-1.74967,0.361275,0.00407913,0.296386 beta-lactamase_2500_D231M,beta-lactamase_2500_231,TEM-1,beta-lactamase_2500,P62593,0.296386,NO,231,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.816,-4.927,4.111,,,E,B,0.75,-1.06,0.319,,65.38,HAB,-0.994,0.361275,0.00107395,0.296386 kka2_1:4_H188E,kka2_1:4_188,Kka2,kka2_1:4,P00552,0.296448,NO,188,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-0.913,-3.211,2.298,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.168804,0.00273139,0.296448 beta-lactamase_I244G,beta-lactamase_244,TEM-1,beta-lactamase,P62593,0.296456,NO,244,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.555,-3.714,2.159,5.35885,,E,B,0.01,-0.84,0.379,,77.62,HHH,-1.385,0.221079,0.00605379,0.296456 kka2_1:8_F133D,kka2_1:8_133,Kka2,kka2_1:8,P00552,0.296564,NO,133,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-0.871,-3.97,3.099,,0.178,,B,1.62,0.43,1.816,,42.42,OHA,-0.871667,0.100394,0.00182168,0.296564 kka2_1:8_F133D,kka2_1:8_133,Kka2,kka2_1:8,P00552,0.296564,NO,133,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-0.871,-3.97,3.099,,0.178,,B,1.62,0.43,1.816,,42.42,OHA,-0.871667,0.100394,0.00182168,0.296564 kka2_1:2_F240G,kka2_1:2_240,Kka2,kka2_1:2,P00552,0.296568,NO,240,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-0.911,-3.675,2.764,,,H,A,0.58,-1.21,0.373,,50.38,BHH,-1.67267,0.295029,0.00552543,0.296568 kka2_1:4_W15D,kka2_1:4_15,Kka2,kka2_1:4,P00552,0.296578,NO,15,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-1.392,-4.212,2.82,,0.01,G,A,0.47,0.15,0.943,,52.27,HHH,-2.10533,0.168804,0.00585505,0.296578 beta-lactamase_156_C75Q,beta-lactamase_156_75,TEM-1,beta-lactamase_156,P62593,0.296628,NO,75,C,Q,CQ,Special,Polar,5.07,6.24429,1.17429,154,121,146,25,108.5,143.8,35.3,-1.245,-4.228,2.983,,,H,A,0.46,-0.87,0.876,,50,HOO,-1.24333,0.111618,0.0034616,0.296628 beta-lactamase_2500_P143R,beta-lactamase_2500_143,TEM-1,beta-lactamase_2500,P62593,0.296708,NO,143,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.967,-3.999,3.032,,0.075,H,A,0.52,-0.37,0.479,,66.78,OOB,-1.354,0.361275,0.00114551,0.296708 kka2_1:1_W24P,kka2_1:1_24,Kka2,kka2_1:1,P00552,0.296744,NO,24,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-1.779,-4.359,2.58,,0.477,E,B,0.47,-0.21,2.375,,56.06,AHH,-2.24467,0.520039,0.00631564,0.296744 Pab1_L133E,Pab1_133,Pab1,Pab1,P04147,0.296755,NO,133,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.039,-3.707,2.668,,0.015,,B,1.75,1.03,,,,PHB,-1.22,0.175299,0.000345939,0.296755 kka2_1:1_R140K,kka2_1:1_140,Kka2,kka2_1:1,P00552,0.296757,NO,140,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.351,-2.269,0.918,,0.12,H,A,1.2,0.2,11.345,11.345,53.03,BBH,-1.885,0.520039,0.00430167,0.296757 kka2_1:1_N195M,kka2_1:1_195,Kka2,kka2_1:1,P00552,0.296764,NO,195,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-0.836,-4.777,3.941,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.520039,0.00276134,0.296764 beta-lactamase_625_N130Y,beta-lactamase_625_130,TEM-1,beta-lactamase_625,P62593,0.296771,NO,130,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-0.798,-4.162,3.364,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.213352,0.000683376,0.296771 beta-lactamase_2500_N130K,beta-lactamase_2500_130,TEM-1,beta-lactamase_2500,P62593,0.2968,NO,130,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-0.798,-3.232,2.434,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.361275,0.000683376,0.2968 beta-lactamase_R162W,beta-lactamase_162,TEM-1,beta-lactamase,P62593,0.296802,NO,162,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.016,-5.367,4.351,5.34456,0.124,S,B,0.68,-0.37,31.656,31.656,64.69,ABH,-1.25,0.221079,0.000561334,0.296802 kka2_1:1_A191I,kka2_1:1_191,Kka2,kka2_1:1,P00552,0.296833,NO,191,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.831,-3.676,2.845,,,.,b,0.46,-0.94,0.53,,50,AHO,-0.868667,0.520039,0.00338807,0.296833 beta-lactamase_2500_K53P,beta-lactamase_2500_53,TEM-1,beta-lactamase_2500,P62593,0.29689,NO,53,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-2.313,-3.069,0.756,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.361275,0.00383383,0.29689 beta-lactamase_156_I140P,beta-lactamase_156_140,TEM-1,beta-lactamase_156,P62593,0.2969,NO,140,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.733,-4.152,2.419,,0.128,H,A,0.48,0.41,1.16,,73.08,PHO,-1.48733,0.111618,0.00597777,0.2969 beta-lactamase_156_T107R,beta-lactamase_156_107,TEM-1,beta-lactamase_156,P62593,0.296939,NO,107,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.117,-3.76,2.643,,,G,A,0.22,-0.06,0.341,,67.83,HPA,-1.265,0.111618,0.00239347,0.296939 kka2_1:4_V214W,kka2_1:4_214,Kka2,kka2_1:4,P00552,0.296953,NO,214,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.261,-5.433,4.172,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.168804,0.00692782,0.296953 kka2_1:1_L260E,kka2_1:1_260,Kka2,kka2_1:1,P00552,0.29701,NO,260,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.741,-3.918,3.177,,0.022,H,A,0.55,-0.52,,,,HHA,-0.845667,0.520039,0.0233782,0.29701 beta-lactamase_2500_T27R,beta-lactamase_2500_27,TEM-1,beta-lactamase_2500,P62593,0.29708,NO,27,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.905,-3.861,1.956,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.361275,0.00306559,0.29708 beta-lactamase_2500_A246L,beta-lactamase_2500_246,TEM-1,beta-lactamase_2500,P62593,0.297085,NO,246,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.121,-1.908,-0.213,,0.01,E,B,0.46,-1.01,0.753,,73.78,HHH,-1.55633,0.361275,0.00569458,0.297085 kka2_1:2_K50I,kka2_1:2_50,Kka2,kka2_1:2,P00552,0.297162,NO,50,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-0.833,-4.062,3.229,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.295029,0.00138626,0.297162 kka2_1:1_A87D,kka2_1:1_87,Kka2,kka2_1:1,P00552,0.297253,NO,87,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.917,-2.332,0.415,,1.039,S,L,0.46,1.57,20.738,20.738,65.53,AHO,-1.822,0.520039,0.00791281,0.297253 beta-lactamase_2500_L135G,beta-lactamase_2500_135,TEM-1,beta-lactamase_2500,P62593,0.297267,NO,135,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.002,-3.837,2.835,,0.117,H,A,0.55,-0.58,0.795,,43.71,PHH,-1.03767,0.361275,0.00244423,0.297267 kka2_1:4_I221D,kka2_1:4_221,Kka2,kka2_1:4,P00552,0.297291,NO,221,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.739,-4.188,2.449,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.168804,0.00945908,0.297291 kka2_1:4_G189L,kka2_1:4_189,Kka2,kka2_1:4,P00552,0.297311,NO,189,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.596,-3.836,3.24,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.168804,0.00253688,0.297311 kka2_1:2_G181P,kka2_1:2_181,Kka2,kka2_1:2,P00552,0.297313,NO,181,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-2.698,-3.097,0.399,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.295029,0.00728319,0.297313 Pab1_A158Y,Pab1_158,Pab1,Pab1,P04147,0.29732,NO,158,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.154,-3.973,2.819,,,,,,,1.197,,56.33,HHP,-1.40733,0.175299,0.000649733,0.29732 beta-lactamase_2500_P181E,beta-lactamase_2500_181,TEM-1,beta-lactamase_2500,P62593,0.297382,NO,181,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.813,-3.466,2.653,,,H,A,0.52,-1.14,1.946,,61.54,HOH,-1.795,0.361275,0.000703122,0.297382 beta-lactamase_I11D,beta-lactamase_11,TEM-1,beta-lactamase,P62593,0.297384,NO,11,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.745,-3.796,2.051,,,,,,,3.135,,66.08,HHO,-1.79467,0.221079,0.00261325,0.297384 kka2_1:8_D216F,kka2_1:8_216,Kka2,kka2_1:8,P00552,0.297403,NO,216,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.785,-4.288,3.503,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.100394,0.00229969,0.297403 kka2_1:8_D216F,kka2_1:8_216,Kka2,kka2_1:8,P00552,0.297403,NO,216,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.785,-4.288,3.503,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.100394,0.00229969,0.297403 kka2_1:8_T225P,kka2_1:8_225,Kka2,kka2_1:8,P00552,0.297403,NO,225,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.393,-4.067,1.674,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.100394,0.0113598,0.297403 kka2_1:8_T225P,kka2_1:8_225,Kka2,kka2_1:8,P00552,0.297403,NO,225,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.393,-4.067,1.674,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.100394,0.0113598,0.297403 beta-lactamase_625_N168H,beta-lactamase_625_168,TEM-1,beta-lactamase_625,P62593,0.29741,NO,168,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-1.029,-4.17,3.141,,0.113,G,A,0.61,-0.4,1.014,,44.41,HPA,-1.13233,0.213352,0.00288667,0.29741 kka2_1:2_G205E,kka2_1:2_205,Kka2,kka2_1:2,P00552,0.297434,NO,205,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.596,-3.693,3.097,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.295029,0.00221855,0.297434 kka2_1:1_T73E,kka2_1:1_73,Kka2,kka2_1:1,P00552,0.297454,NO,73,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.51,-2.977,0.467,,0.309,H,A,0.22,0.35,4.126,,56.06,PPO,-2.02333,0.520039,0.00628605,0.297454 kka2_1:1_T51M,kka2_1:1_51,Kka2,kka2_1:1,P00552,0.297458,NO,51,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.199,-4.634,2.435,,0.05,E,B,0.22,-0.05,3.056,,63.64,BPA,-1.76767,0.520039,0.00628861,0.297458 kka2_1:4_R38N,kka2_1:4_38,Kka2,kka2_1:4,P00552,0.297477,NO,38,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.207,-3.763,2.556,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.168804,0.00372499,0.297477 beta-lactamase_625_C121D,beta-lactamase_625_121,TEM-1,beta-lactamase_625,P62593,0.297524,NO,121,C,D,CD,Special,negativeCharge,5.07,5.0516,-0.0184,154,121,133,12,108.5,111.1,2.6,-0.953,-3.916,2.963,,,H,A,0.46,-0.81,1.143,,63.29,HOP,-1.46767,0.213352,0.000744322,0.297524 kka2_1:8_A215L,kka2_1:8_215,Kka2,kka2_1:8,P00552,0.297543,NO,215,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.968,-3.296,2.328,,0.039,E,B,1.04,-0.59,2.77,,50.38,HHA,-1.00467,0.100394,0.00529129,0.297543 kka2_1:8_A215L,kka2_1:8_215,Kka2,kka2_1:8,P00552,0.297543,NO,215,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.968,-3.296,2.328,,0.039,E,B,1.04,-0.59,2.77,,50.38,HHA,-1.00467,0.100394,0.00529129,0.297543 beta-lactamase_2500_V260D,beta-lactamase_2500_260,TEM-1,beta-lactamase_2500,P62593,0.297546,NO,260,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.361275,0.00471757,0.297546 kka2_1:1_E262M,kka2_1:1_262,Kka2,kka2_1:1,P00552,0.297558,NO,262,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-0.829,-4.701,3.872,,0.059,G,A,1.04,-0.18,0.837,,42.42,AAH,-0.816,0.520039,0.0191586,0.297558 kka2_1:1_G201Q,kka2_1:1_201,Kka2,kka2_1:1,P00552,0.297592,NO,201,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.56,-4.001,2.441,,0.149,T,l,0.29,-0.57,16.092,16.092,52.65,POB,-1.92233,0.520039,0.00820117,0.297592 kka2_1:4_R66Y,kka2_1:4_66,Kka2,kka2_1:4,P00552,0.297624,NO,66,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-0.922,-4.225,3.303,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.168804,0.00161025,0.297624 beta-lactamase_2500_R220W,beta-lactamase_2500_220,TEM-1,beta-lactamase_2500,P62593,0.297626,NO,220,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-0.942,-5.348,4.406,,0.295,I,A,1.2,-0.76,2.175,,74.48,HBP,-1.33633,0.361275,0.00232421,0.297626 kka2_1:1_L39E,kka2_1:1_39,Kka2,kka2_1:1,P00552,0.29772,NO,39,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.223,-3.962,2.739,,,E,B,0.55,-1.21,0.925,,71.59,BHP,-1.69167,0.520039,0.00493618,0.29772 beta-lactamase_625_L120W,beta-lactamase_625_120,TEM-1,beta-lactamase_625,P62593,0.297736,NO,120,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.044,-5.142,4.098,,,H,A,0.55,-1.13,7.813,,64.69,AHO,-1.13633,0.213352,0.00143563,0.297736 kka2_1:1_D134K,kka2_1:1_134,Kka2,kka2_1:1,P00552,0.297744,NO,134,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.969,-3.503,2.534,,0.421,B,B,0.75,0.31,2.329,,49.62,HAB,-1.057,0.520039,0.00270812,0.297744 beta-lactamase_2500_A247K,beta-lactamase_2500_247,TEM-1,beta-lactamase_2500,P62593,0.297778,NO,247,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.361275,0.00611275,0.297778 beta-lactamase_39_A133E,beta-lactamase_39_133,TEM-1,beta-lactamase_39,P62593,0.29778,NO,133,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.186,-3.597,2.411,,,H,A,0.46,-0.86,0.373,,67.83,HHP,-0.988333,0.0495842,0.00468022,0.29778 kka2_1:8_L223Q,kka2_1:8_223,Kka2,kka2_1:8,P00552,0.297822,NO,223,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.861,-4.235,3.374,,,H,A,1.59,-1.24,1.017,,50,HHH,-0.854333,0.100394,0.00253574,0.297822 kka2_1:8_L223Q,kka2_1:8_223,Kka2,kka2_1:8,P00552,0.297822,NO,223,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.861,-4.235,3.374,,,H,A,1.59,-1.24,1.017,,50,HHH,-0.854333,0.100394,0.00253574,0.297822 kka2_1:8_W236P,kka2_1:8_236,Kka2,kka2_1:8,P00552,0.297822,NO,236,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-1.363,-4.32,2.957,,0.303,H,A,1.51,-0.76,1.87,,48.48,AHH,-1.81267,0.100394,0.0088796,0.297822 kka2_1:8_W236P,kka2_1:8_236,Kka2,kka2_1:8,P00552,0.297822,NO,236,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-1.363,-4.32,2.957,,0.303,H,A,1.51,-0.76,1.87,,48.48,AHH,-1.81267,0.100394,0.0088796,0.297822 kka2_1:4_A108I,kka2_1:4_108,Kka2,kka2_1:4,P00552,0.297844,NO,108,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.061,-3.962,1.901,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.168804,0.00751209,0.297844 kka2_1:1_Y244A,kka2_1:1_244,Kka2,kka2_1:1,P00552,0.297882,NO,244,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-0.775,-3.331,2.556,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.520039,0.00453187,0.297882 kka2_1:1_W91F,kka2_1:1_91,Kka2,kka2_1:1,P00552,0.297894,NO,91,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-1.178,-2.297,1.119,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.520039,0.00358653,0.297894 kka2_1:8_I221W,kka2_1:8_221,Kka2,kka2_1:8,P00552,0.297961,NO,221,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.739,-3.219,1.48,,,H,A,1.52,-1.15,1.599,,71.59,AHH,-1.08367,0.100394,0.00945908,0.297961 kka2_1:8_I221W,kka2_1:8_221,Kka2,kka2_1:8,P00552,0.297961,NO,221,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.739,-3.219,1.48,,,H,A,1.52,-1.15,1.599,,71.59,AHH,-1.08367,0.100394,0.00945908,0.297961 beta-lactamase_625_R162P,beta-lactamase_625_162,TEM-1,beta-lactamase_625,P62593,0.298,NO,162,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.016,-2.671,1.655,,0.124,S,B,1.2,-0.37,1.445,,64.69,ABH,-1.25,0.213352,0.000561334,0.298 beta-lactamase_156_I280E,beta-lactamase_156_280,TEM-1,beta-lactamase_156,P62593,0.298006,NO,280,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.111618,0.0530888,0.298006 kka2_1:1_E17A,kka2_1:1_17,Kka2,kka2_1:1,P00552,0.298043,NO,17,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.154,-2.316,0.162,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.520039,0.00688738,0.298043 kka2_1:1_A247I,kka2_1:1_247,Kka2,kka2_1:1,P00552,0.298157,NO,247,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.459,-3.148,0.689,,1.01,S,A,0.46,0.65,7.731,7.731,92.05,HHH,-2.197,0.520039,0.0102428,0.298157 kka2_1:2_A172P,kka2_1:2_172,Kka2,kka2_1:2,P00552,0.298178,NO,172,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.757,-4.041,2.284,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.295029,0.0079265,0.298178 kka2_1:1_P45C,kka2_1:1_45,Kka2,kka2_1:1,P00552,0.298199,NO,45,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.774,-5.158,3.384,,0.669,.,B,0.52,-0.76,4.882,,71.59,BOH,-2.152,0.520039,0.00590481,0.298199 kka2_1:1_V83D,kka2_1:1_83,Kka2,kka2_1:1,P00552,0.298289,NO,83,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-2.567,-3.765,1.198,,0.358,E,B,0.44,0.53,5.931,,71.59,AHH,-2.264,0.520039,0.00650486,0.298289 kka2_1:2_L94Y,kka2_1:2_94,Kka2,kka2_1:2,P00552,0.298354,NO,94,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.618,-4.101,2.483,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.295029,0.00520888,0.298354 Ubiquitin_L71R,Ubiquitin_71,Uba1,Ubiquitin,P0CG48,0.298387,NO,71,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.647,-4.039,2.392,5.02588,0.591,E,B,2.89,-0.69,4.365,,34.31,HHB,-1.85167,0.205827,0.000949314,0.298387 Ubiquitin_L8H,Ubiquitin_8,Uba1,Ubiquitin,P0CG48,0.298387,NO,8,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.723,-3.2,1.477,5.28016,0.664,T,A,0.08,-0.34,0.664,,29.05,PHP,-1.51567,0.205827,0.000726165,0.298387 kka2_1:1_R226D,kka2_1:1_226,Kka2,kka2_1:1,P00552,0.298435,NO,226,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.392,-3.802,2.41,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.520039,0.0108032,0.298435 beta-lactamase_2500_G142C,beta-lactamase_2500_142,TEM-1,beta-lactamase_2500,P62593,0.298449,NO,142,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.707,-5.05,4.343,,0.034,,p,0.29,-0.64,1.883,,64.69,OOO,-0.834,0.361275,0.00060149,0.298449 kka2_1:4_G189T,kka2_1:4_189,Kka2,kka2_1:4,P00552,0.298464,NO,189,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.596,-3.675,3.079,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.168804,0.00253688,0.298464 kka2_1:1_L94A,kka2_1:1_94,Kka2,kka2_1:1,P00552,0.298471,NO,94,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.618,-3.195,1.577,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.520039,0.00520888,0.298471 kka2_1:4_P109Y,kka2_1:4_109,Kka2,kka2_1:4,P00552,0.298504,NO,109,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.412,-4.295,2.883,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.168804,0.0070929,0.298504 kka2_1:1_E63Y,kka2_1:1_63,Kka2,kka2_1:1,P00552,0.298516,NO,63,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-0.762,-4.191,3.429,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.520039,0.00118399,0.298516 beta-lactamase_156_V259G,beta-lactamase_156_259,TEM-1,beta-lactamase_156,P62593,0.298531,NO,259,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.111618,0.0070773,0.298531 kka2_1:1_N195H,kka2_1:1_195,Kka2,kka2_1:1,P00552,0.298542,NO,195,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-0.836,-4.094,3.258,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.520039,0.00276134,0.298542 kka2_1:1_C77T,kka2_1:1_77,Kka2,kka2_1:1,P00552,0.298597,NO,77,C,T,CT,Special,Polar,5.07,5.6,0.53,149,121,119,-2,108.5,116.1,7.6,-1.477,-3.496,2.019,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.520039,0.00441216,0.298597 beta-lactamase_625_C121W,beta-lactamase_625_121,TEM-1,beta-lactamase_625,P62593,0.298703,NO,121,C,W,CW,Special,Hydrophobic,5.07,5.89,0.82,215,121,204,83,108.5,227.8,119.3,-0.953,-5.146,4.193,,,H,A,0.46,-0.81,1.143,,63.29,HOP,-1.46767,0.213352,0.000744322,0.298703 kka2_1:1_L103H,kka2_1:1_103,Kka2,kka2_1:1,P00552,0.298718,NO,103,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-2.362,-4.862,2.5,,0.394,T,A,0.55,-0.99,4.121,,63.64,HHP,-1.534,0.520039,0.00574792,0.298718 kka2_1:1_E111K,kka2_1:1_111,Kka2,kka2_1:1,P00552,0.298724,NO,111,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.28,-2.698,0.418,,0.155,H,A,1.52,-1.14,15.716,15.716,65.53,HAB,-2.27833,0.520039,0.00746789,0.298724 kka2_1:1_L67W,kka2_1:1_67,Kka2,kka2_1:1,P00552,0.298729,NO,67,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.741,-5.126,4.385,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.520039,0.00102787,0.298729 kka2_1:1_G189A,kka2_1:1_189,Kka2,kka2_1:1,P00552,0.298803,NO,189,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.596,-2.881,2.285,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.520039,0.00253688,0.298803 kka2_1:2_R140D,kka2_1:2_140,Kka2,kka2_1:2,P00552,0.298838,NO,140,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.351,-3.692,2.341,,0.12,H,A,1.2,0.2,0.352,,53.03,BBH,-1.885,0.295029,0.00430167,0.298838 kka2_1:2_R211Q,kka2_1:2_211,Kka2,kka2_1:2,P00552,0.298856,NO,211,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-0.899,-3.552,2.653,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.295029,0.00204888,0.298856 kka2_1:1_L103D,kka2_1:1_103,Kka2,kka2_1:1,P00552,0.298883,NO,103,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-2.362,-3.76,1.398,,0.394,T,A,0.55,-0.99,4.121,,63.64,HHP,-1.534,0.520039,0.00574792,0.298883 kka2_1:2_R211P,kka2_1:2_211,Kka2,kka2_1:2,P00552,0.298891,NO,211,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-0.899,-3.968,3.069,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.295029,0.00204888,0.298891 kka2_1:1_R226Y,kka2_1:1_226,Kka2,kka2_1:1,P00552,0.298918,NO,226,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.392,-3.976,2.584,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.520039,0.0108032,0.298918 kka2_1:1_P249I,kka2_1:1_249,Kka2,kka2_1:1,P00552,0.298934,NO,249,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.867,-2.381,0.514,,0.406,.,B,0.52,-0.01,8.037,8.037,92.05,HOA,-1.66867,0.520039,0.011045,0.298934 kka2_1:2_P194M,kka2_1:2_194,Kka2,kka2_1:2,P00552,0.298981,NO,194,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.846,-4.773,3.927,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.295029,0.00314194,0.298981 kka2_1:4_E63N,kka2_1:4_63,Kka2,kka2_1:4,P00552,0.299013,NO,63,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-0.762,-3.476,2.714,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.168804,0.00118399,0.299013 beta-lactamase_2500_S201W,beta-lactamase_2500_201,TEM-1,beta-lactamase_2500,P62593,0.299031,NO,201,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.183,-5.344,4.161,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.361275,0.00198815,0.299031 beta-lactamase_625_G281E,beta-lactamase_625_281,TEM-1,beta-lactamase_625,P62593,0.299062,NO,281,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.213352,0.0406482,0.299062 kka2_1:8_V214S,kka2_1:8_214,Kka2,kka2_1:8,P00552,0.299075,NO,214,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.261,-3.744,2.483,,0.117,E,B,1.48,-0.31,1.859,,64.39,OHH,-0.941667,0.100394,0.00692782,0.299075 kka2_1:8_V214S,kka2_1:8_214,Kka2,kka2_1:8,P00552,0.299075,NO,214,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.261,-3.744,2.483,,0.117,E,B,1.48,-0.31,1.859,,64.39,OHH,-0.941667,0.100394,0.00692782,0.299075 kka2_1:1_F256T,kka2_1:1_256,Kka2,kka2_1:1,P00552,0.299077,NO,256,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.49,-3.783,2.293,,,H,A,1.62,-0.78,2.354,,53.03,HHH,-1.423,0.520039,0.0132841,0.299077 beta-lactamase_625_L160E,beta-lactamase_625_160,TEM-1,beta-lactamase_625,P62593,0.299101,NO,160,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.977,-3.906,2.929,,0.022,,B,0.55,-0.6,0.237,,44.41,BHA,-0.936,0.213352,0.00193775,0.299101 beta-lactamase_G142Y,beta-lactamase_142,TEM-1,beta-lactamase,P62593,0.299129,NO,142,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.707,-4.385,3.678,4.55474,0.034,,p,0.77,-0.64,1.947,,64.69,OOO,-0.834,0.221079,0.00060149,0.299129 kka2_1:1_A64H,kka2_1:1_64,Kka2,kka2_1:1,P00552,0.299205,NO,64,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.496,-4.947,3.451,,0.039,H,A,0.46,-0.57,1.175,,56.06,AHH,-1.334,0.520039,0.00705578,0.299205 kka2_1:2_S105M,kka2_1:2_105,Kka2,kka2_1:2,P00552,0.299209,NO,105,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.945,-4.741,2.796,,0.056,S,B,0.27,-1.04,3.442,,65.53,PPB,-2.17033,0.295029,0.00847233,0.299209 kka2_1:4_L67W,kka2_1:4_67,Kka2,kka2_1:4,P00552,0.299244,NO,67,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.741,-5.126,4.385,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.168804,0.00102787,0.299244 beta-lactamase_2500_G240I,beta-lactamase_2500_240,TEM-1,beta-lactamase_2500,P62593,0.299262,NO,240,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.361275,0.00591201,0.299262 beta-lactamase_S201E,beta-lactamase_201,TEM-1,beta-lactamase,P62593,0.299313,NO,201,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.183,-3.352,2.169,4.85496,0.064,H,A,0.77,-0.07,4.045,,64.69,HPB,-1.451,0.221079,0.00198815,0.299313 beta-lactamase_G248W,beta-lactamase_248,TEM-1,beta-lactamase,P62593,0.299383,NO,248,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.794,-1.801,0.007,4.69798,,E,b,0.23,-0.43,1.782,,61.19,HOO,-1.52867,0.221079,0.00428493,0.299383 kka2_1:1_P128M,kka2_1:1_128,Kka2,kka2_1:1,P00552,0.299405,NO,128,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.922,-4.47,2.548,,0.316,G,A,0.52,0.4,2.178,,56.06,AOH,-1.64733,0.520039,0.00774689,0.299405 beta-lactamase_2500_N168R,beta-lactamase_2500_168,TEM-1,beta-lactamase_2500,P62593,0.29946,NO,168,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-1.029,-3.58,2.551,,0.113,G,A,0.61,-0.4,2.9,,44.41,HPA,-1.13233,0.361275,0.00288667,0.29946 kka2_1:8_A144D,kka2_1:8_144,Kka2,kka2_1:8,P00552,0.299491,NO,144,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.859,-3.804,2.945,,,H,A,1.04,0.21,1.118,,52.65,BHB,-1.72933,0.100394,0.00231095,0.299491 kka2_1:8_A144D,kka2_1:8_144,Kka2,kka2_1:8,P00552,0.299491,NO,144,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.859,-3.804,2.945,,,H,A,1.04,0.21,1.118,,52.65,BHB,-1.72933,0.100394,0.00231095,0.299491 kka2_1:8_A144L,kka2_1:8_144,Kka2,kka2_1:8,P00552,0.299491,NO,144,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.859,-3.107,2.248,,,H,A,1.04,0.21,1.118,,52.65,BHB,-1.72933,0.100394,0.00231095,0.299491 kka2_1:8_A144L,kka2_1:8_144,Kka2,kka2_1:8,P00552,0.299491,NO,144,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.859,-3.107,2.248,,,H,A,1.04,0.21,1.118,,52.65,BHB,-1.72933,0.100394,0.00231095,0.299491 kka2_1:8_N195F,kka2_1:8_195,Kka2,kka2_1:8,P00552,0.299491,NO,195,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-0.836,-4.344,3.508,,0.037,G,A,0.43,-1.36,1.108,,48.11,OPH,-1.26567,0.100394,0.00276134,0.299491 kka2_1:8_N195F,kka2_1:8_195,Kka2,kka2_1:8,P00552,0.299491,NO,195,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-0.836,-4.344,3.508,,0.037,G,A,0.43,-1.36,1.108,,48.11,OPH,-1.26567,0.100394,0.00276134,0.299491 kka2_1:8_V185K,kka2_1:8_185,Kka2,kka2_1:8,P00552,0.299491,NO,185,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.045,-3.785,2.74,,0.058,E,B,1.48,-0.49,1.234,,46.97,HHH,-1.184,0.100394,0.00367031,0.299491 kka2_1:8_V185K,kka2_1:8_185,Kka2,kka2_1:8,P00552,0.299491,NO,185,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.045,-3.785,2.74,,0.058,E,B,1.48,-0.49,1.234,,46.97,HHH,-1.184,0.100394,0.00367031,0.299491 kka2_1:2_S32L,kka2_1:2_32,Kka2,kka2_1:2,P00552,0.299544,NO,32,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-0.804,-3.386,2.582,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.295029,0.00149998,0.299544 kka2_1:2_Y257E,kka2_1:2_257,Kka2,kka2_1:2,P00552,0.299612,NO,257,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-1.064,-3.82,2.756,,0.022,H,A,0.21,-0.88,0.833,,52.65,HHB,-1.39333,0.295029,0.0148191,0.299612 kka2_1:4_L174E,kka2_1:4_174,Kka2,kka2_1:4,P00552,0.299693,NO,174,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.952,-3.9,2.948,,,H,A,0.55,-0.31,1.339,,51.89,BHB,-2.08533,0.168804,0.00438501,0.299693 kka2_1:2_G210A,kka2_1:2_210,Kka2,kka2_1:2,P00552,0.299793,NO,210,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.095,-2.003,0.908,,0.103,T,A,0.29,-0.62,0.271,,50,OOB,-0.966667,0.295029,0.00598378,0.299793 kka2_1:4_V153S,kka2_1:4_153,Kka2,kka2_1:4,P00552,0.29982,NO,153,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.092,-3.643,2.551,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.168804,0.00501119,0.29982 kka2_1:1_R140M,kka2_1:1_140,Kka2,kka2_1:1,P00552,0.2999,NO,140,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.351,-4.639,3.288,,0.12,H,A,1.2,0.2,11.345,11.345,53.03,BBH,-1.885,0.520039,0.00430167,0.2999 kka2_1:8_R211W,kka2_1:8_211,Kka2,kka2_1:8,P00552,0.299907,NO,211,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-0.899,-2.964,2.065,,0.12,T,a,0.16,-0.39,0.615,,49.62,OBH,-0.966,0.100394,0.00204888,0.299907 kka2_1:8_R211W,kka2_1:8_211,Kka2,kka2_1:8,P00552,0.299907,NO,211,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-0.899,-2.964,2.065,,0.12,T,a,0.16,-0.39,0.615,,49.62,OBH,-0.966,0.100394,0.00204888,0.299907 beta-lactamase_39_N130I,beta-lactamase_39_130,TEM-1,beta-lactamase_39,P62593,0.299929,NO,130,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-0.798,-4.01,3.212,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.0495842,0.000683376,0.299929 kka2_1:1_G55F,kka2_1:1_55,Kka2,kka2_1:1,P00552,0.299942,NO,55,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.625,-3.32,1.695,,0.517,S,b,0.29,1.19,4.035,,63.64,POH,-2.05967,0.520039,0.00667877,0.299942 kka2_1:1_K175Y,kka2_1:1_175,Kka2,kka2_1:1,P00552,0.300108,NO,175,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-2.897,-3.379,0.482,,0.579,H,A,1.3,0.51,9.33,9.33,71.59,HBH,-1.82333,0.520039,0.00693093,0.300108 beta-lactamase_2500_F228D,beta-lactamase_2500_228,TEM-1,beta-lactamase_2500,P62593,0.300118,NO,228,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-2.342,-3.807,1.465,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.361275,0.0046669,0.300118 beta-lactamase_39_N130R,beta-lactamase_39_130,TEM-1,beta-lactamase_39,P62593,0.300161,NO,130,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-0.798,-3.483,2.685,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.0495842,0.000683376,0.300161 beta-lactamase_Y44G,beta-lactamase_44,TEM-1,beta-lactamase,P62593,0.300179,NO,44,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-2.547,-3.687,1.14,5.6273,,E,B,2.55,-0.45,2.683,,73.78,OHH,-1.86267,0.221079,0.00426364,0.300179 kka2_1:1_G151F,kka2_1:1_151,Kka2,kka2_1:1,P00552,0.30021,NO,151,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.873,-4.384,3.511,,0.678,T,l,0.29,1.36,0.226,,49.62,HOH,-1.11433,0.520039,0.00339918,0.30021 kka2_1:2_S204E,kka2_1:2_204,Kka2,kka2_1:2,P00552,0.30024,NO,204,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.353,-3.494,2.141,,0.144,E,A,0.27,-1.2,2.442,,65.53,HPO,-0.953333,0.295029,0.00881794,0.30024 kka2_1:8_C77D,kka2_1:8_77,Kka2,kka2_1:8,P00552,0.300323,NO,77,C,D,CD,Special,negativeCharge,5.07,5.0516,-0.0184,154,121,133,12,108.5,111.1,2.6,-1.477,-3.887,2.41,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.100394,0.00441216,0.300323 kka2_1:8_C77D,kka2_1:8_77,Kka2,kka2_1:8,P00552,0.300323,NO,77,C,D,CD,Special,negativeCharge,5.07,5.0516,-0.0184,154,121,133,12,108.5,111.1,2.6,-1.477,-3.887,2.41,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.100394,0.00441216,0.300323 beta-lactamase_39_G43V,beta-lactamase_39_43,TEM-1,beta-lactamase_39,P62593,0.300324,NO,43,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.62,-3.754,3.134,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.0495842,0.00120151,0.300324 beta-lactamase_2500_L205T,beta-lactamase_2500_205,TEM-1,beta-lactamase_2500,P62593,0.300343,NO,205,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.922,-3.476,2.554,,,H,A,0.55,-0.46,0.831,,42.31,PHH,-1.57767,0.361275,0.00255802,0.300343 kka2_1:1_Q42C,kka2_1:1_42,Kka2,kka2_1:1,P00552,0.300348,NO,42,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.907,-5.227,2.32,,1.044,T,B,0.4,-0.8,2.792,,71.59,HPO,-2.12433,0.520039,0.00679212,0.300348 kka2_1:4_Y22G,kka2_1:4_22,Kka2,kka2_1:4,P00552,0.300429,NO,22,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-1.583,-2.411,0.828,,0.122,.,B,0.21,-0.8,1.838,,65.53,OHA,-1.80333,0.168804,0.00598977,0.300429 beta-lactamase_2500_M66S,beta-lactamase_2500_66,TEM-1,beta-lactamase_2500,P62593,0.300432,NO,66,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.362,-3.571,2.209,,0.013,,A,0.55,-0.7,0.502,,73.08,OHH,-1.49567,0.361275,0.00412876,0.300432 kka2_1:8_H124Y,kka2_1:8_124,Kka2,kka2_1:8,P00552,0.300461,NO,124,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-0.84,-3.291,2.451,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.100394,0.00211296,0.300461 kka2_1:8_H124Y,kka2_1:8_124,Kka2,kka2_1:8,P00552,0.300461,NO,124,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-0.84,-3.291,2.451,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.100394,0.00211296,0.300461 beta-lactamase_2500_T131D,beta-lactamase_2500_131,TEM-1,beta-lactamase_2500,P62593,0.300534,NO,131,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.328,-3.605,2.277,,,H,A,0.22,-0.69,3.048,,67.48,PPH,-1.00867,0.361275,0.00345886,0.300534 beta-lactamase_156_L120P,beta-lactamase_156_120,TEM-1,beta-lactamase_156,P62593,0.300538,NO,120,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.044,-4.17,3.126,,,H,A,0.55,-1.13,7.813,,64.69,AHO,-1.13633,0.111618,0.00143563,0.300538 kka2_1:1_E262V,kka2_1:1_262,Kka2,kka2_1:1,P00552,0.300677,NO,262,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-0.829,-3.58,2.751,,0.059,G,A,1.04,-0.18,0.837,,42.42,AAH,-0.816,0.520039,0.0191586,0.300677 kka2_1:2_D216M,kka2_1:2_216,Kka2,kka2_1:2,P00552,0.300759,NO,216,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.785,-4.956,4.171,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.295029,0.00229969,0.300759 beta-lactamase_2500_D48L,beta-lactamase_2500_48,TEM-1,beta-lactamase_2500,P62593,0.300771,NO,48,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.101,-3.744,2.643,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.361275,0.0027273,0.300771 PSD95pdz3_A375F,PSD95pdz3_375,PSD95pdz3,PSD95pdz3,P31016,0.300802,NO,375,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.307,-3.749,2.442,5.05512,,,,,13.888,,,,PHH,-1.43767,0.0758425,0.000356809,0.300802 beta-lactamase_I45D,beta-lactamase_45,TEM-1,beta-lactamase,P62593,0.300805,NO,45,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-2.421,-3.902,1.481,5.31505,,E,B,1,-0.3,2.256,,77.62,HHA,-2.30267,0.221079,0.00452842,0.300805 beta-lactamase_2500_T179Y,beta-lactamase_2500_179,TEM-1,beta-lactamase_2500,P62593,0.300847,NO,179,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.085,-4.097,3.012,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.361275,0.00226045,0.300847 kka2_1:2_L19S,kka2_1:2_19,Kka2,kka2_1:2,P00552,0.30086,NO,19,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.254,-3.764,2.51,,0.08,T,A,0.55,-0.26,17.165,17.165,65.53,BHH,-2.221,0.295029,0.00620703,0.30086 kka2_1:8_L241E,kka2_1:8_241,Kka2,kka2_1:8,P00552,0.300876,NO,241,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.158,-4.005,2.847,,0.08,H,A,1.59,-0.82,1.136,,63.26,HHH,-1.58533,0.100394,0.0117299,0.300876 kka2_1:8_L241E,kka2_1:8_241,Kka2,kka2_1:8,P00552,0.300876,NO,241,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.158,-4.005,2.847,,0.08,H,A,1.59,-0.82,1.136,,63.26,HHH,-1.58533,0.100394,0.0117299,0.300876 kka2_1:1_P12K,kka2_1:1_12,Kka2,kka2_1:1,P00552,0.300881,NO,12,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.853,-3.495,2.642,,,.,B,0.52,1.25,0.261,,48.11,POH,-1.80767,0.520039,0.00500011,0.300881 beta-lactamase_2500_I277W,beta-lactamase_2500_277,TEM-1,beta-lactamase_2500,P62593,0.300932,NO,277,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.361275,0.0169305,0.300932 beta-lactamase_0_S128M,beta-lactamase_0_128,TEM-1,beta-lactamase_0,P62593,0.300943,NO,128,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-0.84,-4.48,3.64,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.0500837,0.00071483,0.300943 kka2_1:1_N195E,kka2_1:1_195,Kka2,kka2_1:1,P00552,0.300951,NO,195,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-0.836,-3.211,2.375,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.520039,0.00276134,0.300951 kka2_1:1_T85E,kka2_1:1_85,Kka2,kka2_1:1,P00552,0.300981,NO,85,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.165,-2.512,0.347,,0.576,E,B,0.82,1.39,16.653,16.653,71.59,HPA,-2.10133,0.520039,0.00634493,0.300981 beta-lactamase_2500_T69Q,beta-lactamase_2500_69,TEM-1,beta-lactamase_2500,P62593,0.300999,NO,69,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-0.973,-3.935,2.962,,,G,A,0.22,-1.24,2.05,,93.01,PPH,-1.01833,0.361275,0.00127498,0.300999 kka2_1:1_I115P,kka2_1:1_115,Kka2,kka2_1:1,P00552,0.301024,NO,115,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.606,-4.209,2.603,,0.105,H,A,0.48,-1.18,0.878,,65.53,PHH,-2.205,0.520039,0.00836567,0.301024 beta-lactamase_0_G76C,beta-lactamase_0_76,TEM-1,beta-lactamase_0,P62593,0.301031,NO,76,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.189,-4.823,3.634,,,H,A,0.29,-0.67,1.188,,67.83,OOH,-1.22267,0.0500837,0.00476637,0.301031 beta-lactamase_2500_I277T,beta-lactamase_2500_277,TEM-1,beta-lactamase_2500,P62593,0.301061,NO,277,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.361275,0.0169305,0.301061 kka2_1:4_R226D,kka2_1:4_226,Kka2,kka2_1:4,P00552,0.301106,NO,226,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.392,-3.802,2.41,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.168804,0.0108032,0.301106 kka2_1:1_L57I,kka2_1:1_57,Kka2,kka2_1:1,P00552,0.301112,NO,57,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.898,-2.89,0.992,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.520039,0.00723769,0.301112 beta-lactamase_39_T179P,beta-lactamase_39_179,TEM-1,beta-lactamase_39,P62593,0.301145,NO,179,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.085,-3.739,2.654,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.0495842,0.00226045,0.301145 gb1_A260F,gb1_260,gb1,gb1,P06654,0.301194,NO,260,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.486,-3.746,2.26,,,,,,,0.173,,9.6,HHP,-1.70967,0.177985,0.0055808,0.301194 gb1_N261A,gb1_261,gb1,gb1,P06654,0.301194,NO,261,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-1.863,-2.778,0.915,,,,,,,1.191,,44.87,HPA,-2.16033,0.177985,0.0061875,0.301194 gb1_W269F,gb1_269,gb1,gb1,P06654,0.301194,NO,269,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-1.198,-3.169,1.971,,,,,,,,,,AHP,-2.08867,0.177985,0.00270706,0.301194 gb1_Y271E,gb1_271,gb1,gb1,P06654,0.301194,NO,271,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-1.181,-3.442,2.261,,,,,,,,,,PHA,-1.92933,0.177985,0.00236544,0.301194 beta-lactamase_625_R257G,beta-lactamase_625_257,TEM-1,beta-lactamase_625,P62593,0.301298,NO,257,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.213352,0.00756629,0.301298 hsp90_W585C,hsp90_585,hsp90,hsp90,P02829,0.301354,NO,585,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-4.251,-4.015,0,5.31455,0.508,,B,1.22,0.43,,,,OHP,-3.17533,0.368192,0.000222939,0.301354 kka2_1:8_D261T,kka2_1:8_261,Kka2,kka2_1:8,P00552,0.301428,NO,261,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.708,-3.45,2.742,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.100394,0.0224846,0.301428 kka2_1:8_D261T,kka2_1:8_261,Kka2,kka2_1:8,P00552,0.301428,NO,261,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.708,-3.45,2.742,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.100394,0.0224846,0.301428 WW_domain_Y188H,WW_domain_188,Yap65,WW_domain,P46937,0.301433,NO,188,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-1.326,-3.771,2.445,5.89734,,,,,,,,,BHH,-1.45333,0.153962,0.00265487,0.301433 kka2_1:1_A87T,kka2_1:1_87,Kka2,kka2_1:1,P00552,0.30145,NO,87,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.917,-3.035,1.118,,1.039,S,L,0.46,1.57,20.738,20.738,65.53,AHO,-1.822,0.520039,0.00791281,0.30145 beta-lactamase_G142M,beta-lactamase_142,TEM-1,beta-lactamase,P62593,0.301456,NO,142,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.707,-4.893,4.186,4.55474,0.034,,p,0.77,-0.64,1.947,,64.69,OOO,-0.834,0.221079,0.00060149,0.301456 beta-lactamase_2500_A84P,beta-lactamase_2500_84,TEM-1,beta-lactamase_2500,P62593,0.301506,NO,84,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.651,-3.933,2.282,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.361275,0.00503822,0.301506 kka2_1:1_G245N,kka2_1:1_245,Kka2,kka2_1:1,P00552,0.301507,NO,245,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.812,-2.694,1.882,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.520039,0.00683899,0.301507 kka2_1:1_P179S,kka2_1:1_179,Kka2,kka2_1:1,P00552,0.301529,NO,179,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.974,-2.711,1.737,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.520039,0.00298346,0.301529 kka2_1:1_R66Y,kka2_1:1_66,Kka2,kka2_1:1,P00552,0.301602,NO,66,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-0.922,-4.225,3.303,,0.103,H,A,1.2,-0.2,2.659,,46.21,HBH,-1.13567,0.520039,0.00161025,0.301602 kka2_1:1_R145E,kka2_1:1_145,Kka2,kka2_1:1,P00552,0.301769,NO,145,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.804,-2.289,0.485,,0.346,H,A,1.2,1.23,23.699,23.699,63.64,HBP,-1.88033,0.520039,0.00846663,0.301769 kka2_1:1_A110G,kka2_1:1_110,Kka2,kka2_1:1,P00552,0.30177,NO,110,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.064,-2.863,0.799,,0.175,H,A,1.04,-1.19,11.755,,71.59,OHA,-1.91867,0.520039,0.00759851,0.30177 kka2_1:2_H162L,kka2_1:2_162,Kka2,kka2_1:2,P00552,0.301807,NO,162,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-2.319,-3.554,1.235,,0.071,G,A,0.17,1.01,3.187,,64.39,ABP,-2.02067,0.295029,0.00616145,0.301807 kka2_1:4_C131W,kka2_1:4_131,Kka2,kka2_1:4,P00552,0.301842,NO,131,C,W,CW,Special,Hydrophobic,5.07,5.89,0.82,215,121,204,83,108.5,227.8,119.3,-0.831,-5.126,4.295,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.168804,0.00170814,0.301842 beta-lactamase_2500_S266Y,beta-lactamase_2500_266,TEM-1,beta-lactamase_2500,P62593,0.301853,NO,266,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.361275,0.0140785,0.301853 kka2_1:2_A224R,kka2_1:2_224,Kka2,kka2_1:2,P00552,0.301867,NO,224,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.977,-3.85,2.873,,,H,A,0.46,-1.26,1.646,,63.64,HHP,-1.41033,0.295029,0.00352047,0.301867 beta-lactamase_0_T126V,beta-lactamase_0_126,TEM-1,beta-lactamase_0,P62593,0.302056,NO,126,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.122,-3.336,2.214,,0.05,H,A,0.22,-0.05,0.705,,44.41,HPH,-1.60467,0.0500837,0.00244552,0.302056 kka2_1:2_H188A,kka2_1:2_188,Kka2,kka2_1:2,P00552,0.302122,NO,188,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-0.913,-3.329,2.416,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.295029,0.00273139,0.302122 kka2_1:2_V49H,kka2_1:2_49,Kka2,kka2_1:2,P00552,0.302175,NO,49,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.614,-5.018,3.404,,,E,B,0.44,-0.77,1.233,,64.39,HHB,-1.3,0.295029,0.00615685,0.302175 kka2_1:1_F171K,kka2_1:1_171,Kka2,kka2_1:1,P00552,0.302218,NO,171,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.326,-3.945,2.619,,0.154,H,A,1.62,-0.1,13.679,13.679,63.64,HHH,-1.45433,0.520039,0.00821426,0.302218 kka2_1:1_D159A,kka2_1:1_159,Kka2,kka2_1:1,P00552,0.302222,NO,159,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.82,-3.286,2.466,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.520039,0.0030485,0.302222 kka2_1:8_R211Q,kka2_1:8_211,Kka2,kka2_1:8,P00552,0.302255,NO,211,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-0.899,-3.552,2.653,,0.12,T,a,0.16,-0.39,0.615,,49.62,OBH,-0.966,0.100394,0.00204888,0.302255 kka2_1:8_R211Q,kka2_1:8_211,Kka2,kka2_1:8,P00552,0.302255,NO,211,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-0.899,-3.552,2.653,,0.12,T,a,0.16,-0.39,0.615,,49.62,OBH,-0.966,0.100394,0.00204888,0.302255 Pab1_G150E,Pab1_150,Pab1,Pab1,P04147,0.302261,NO,150,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.809,-3.482,2.673,,0.287,S,b,0.23,0.53,,,,HOA,-1.45233,0.175299,0.000323835,0.302261 kka2_1:2_A191I,kka2_1:2_191,Kka2,kka2_1:2,P00552,0.302264,NO,191,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.831,-3.676,2.845,,,.,b,0.46,-0.94,2.046,,50,AHO,-0.868667,0.295029,0.00338807,0.302264 kka2_1:1_R211H,kka2_1:1_211,Kka2,kka2_1:1,P00552,0.302269,NO,211,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-0.899,-4.319,3.42,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.520039,0.00204888,0.302269 beta-lactamase_625_D207P,beta-lactamase_625_207,TEM-1,beta-lactamase_625,P62593,0.302346,NO,207,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.064,-3.955,1.891,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.213352,0.00592942,0.302346 kka2_1:1_E230M,kka2_1:1_230,Kka2,kka2_1:1,P00552,0.302359,NO,230,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.672,-4.815,2.143,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.520039,0.00920051,0.302359 E1_Ubiquitin_L43R,E1_Ubiquitin_43,Uba1,E1_Ubiquitin,P0CG63,0.302387,NO,43,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.188,-3.744,2.556,,,E,B,,-1.17,,,,BHH,-1.30733,0.18783,0.00190185,0.302387 beta-lactamase_2500_L188H,beta-lactamase_2500_188,TEM-1,beta-lactamase_2500,P62593,0.302394,NO,188,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.166,-4.872,3.706,,,H,A,0.55,-0.3,17.865,17.865,60.14,PHB,-1.47033,0.361275,0.00295687,0.302394 Pab1_K156G,Pab1_156,Pab1,Pab1,P04147,0.302395,NO,156,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.083,-3.175,2.092,,0.406,E,B,1.82,-0.26,,,,PBH,-1.58167,0.175299,0.000316767,0.302395 beta-lactamase_625_T178H,beta-lactamase_625_178,TEM-1,beta-lactamase_625,P62593,0.302408,NO,178,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-0.791,-4.68,3.889,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.213352,0.000684366,0.302408 beta-lactamase_625_N168L,beta-lactamase_625_168,TEM-1,beta-lactamase_625,P62593,0.302418,NO,168,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-1.029,-3.516,2.487,,0.113,G,A,0.61,-0.4,1.014,,44.41,HPA,-1.13233,0.213352,0.00288667,0.302418 beta-lactamase_156_N130I,beta-lactamase_156_130,TEM-1,beta-lactamase_156,P62593,0.302447,NO,130,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-0.798,-4.01,3.212,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.111618,0.000683376,0.302447 kka2_1:2_D90I,kka2_1:2_90,Kka2,kka2_1:2,P00552,0.30251,NO,90,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.459,-3.293,0.834,,0.104,E,B,0.75,0.73,6.085,,64.39,BAH,-1.72833,0.295029,0.00583842,0.30251 beta-lactamase_2500_G249S,beta-lactamase_2500_249,TEM-1,beta-lactamase_2500,P62593,0.302512,NO,249,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.312,,,,0.256,S,B,0.23,0.04,30.841,30.841,72.73,HOO,-1.81367,0.361275,0.00220169,0.302512 beta-lactamase_2500_T27G,beta-lactamase_2500_27,TEM-1,beta-lactamase_2500,P62593,0.30252,NO,27,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.905,-3.36,1.455,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.361275,0.00306559,0.30252 beta-lactamase_G239Y,beta-lactamase_239,TEM-1,beta-lactamase,P62593,0.302561,NO,239,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.819,-4.364,3.545,4.85529,0.115,T,l,0.77,-0.62,1.817,,42.31,BOP,-1.45267,0.221079,0.00213852,0.302561 beta-lactamase_39_I125Y,beta-lactamase_39_125,TEM-1,beta-lactamase_39,P62593,0.302689,NO,125,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.441,-4.111,2.67,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.0495842,0.00383964,0.302689 kka2_1:2_W236K,kka2_1:2_236,Kka2,kka2_1:2,P00552,0.302788,NO,236,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-1.363,-3.959,2.596,,0.303,H,A,1.51,-0.76,5.58,,48.48,AHH,-1.81267,0.295029,0.0088796,0.302788 kka2_1:8_I228P,kka2_1:8_228,Kka2,kka2_1:8,P00552,0.302805,NO,228,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.142,-4.165,3.023,,,H,A,1.52,-1.2,1.521,,71.59,AHH,-1.54633,0.100394,0.00458834,0.302805 kka2_1:8_I228P,kka2_1:8_228,Kka2,kka2_1:8,P00552,0.302805,NO,228,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.142,-4.165,3.023,,,H,A,1.52,-1.2,1.521,,71.59,AHH,-1.54633,0.100394,0.00458834,0.302805 kka2_1:8_A222M,kka2_1:8_222,Kka2,kka2_1:8,P00552,0.302844,NO,222,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.725,-4.508,3.783,,,H,A,1.04,-1.21,,,,HHH,-1.10833,0.100394,0.00207657,0.302844 kka2_1:8_A222M,kka2_1:8_222,Kka2,kka2_1:8,P00552,0.302844,NO,222,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.725,-4.508,3.783,,,H,A,1.04,-1.21,,,,HHH,-1.10833,0.100394,0.00207657,0.302844 beta-lactamase_625_A133P,beta-lactamase_625_133,TEM-1,beta-lactamase_625,P62593,0.302845,NO,133,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.186,-3.811,2.625,,,H,A,0.46,-0.86,0.373,,67.83,HHP,-0.988333,0.213352,0.00468022,0.302845 beta-lactamase_156_L120R,beta-lactamase_156_120,TEM-1,beta-lactamase_156,P62593,0.302881,NO,120,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.044,-2.871,1.827,,,H,A,0.55,-1.13,7.813,,64.69,AHO,-1.13633,0.111618,0.00143563,0.302881 kka2_1:4_R253E,kka2_1:4_253,Kka2,kka2_1:4,P00552,0.30295,NO,253,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.356,-3.329,1.973,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.168804,0.0144195,0.30295 kka2_1:1_A64N,kka2_1:1_64,Kka2,kka2_1:1,P00552,0.302992,NO,64,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.496,-4.101,2.605,,0.039,H,A,0.46,-0.57,1.175,,56.06,AHH,-1.334,0.520039,0.00705578,0.302992 beta-lactamase_I125Q,beta-lactamase_125,TEM-1,beta-lactamase,P62593,0.303085,NO,125,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.441,-4.226,2.785,5.23481,,H,A,2.82,-0.7,2.301,,63.29,HHP,-1.248,0.221079,0.00383964,0.303085 beta-lactamase_156_L136F,beta-lactamase_156_136,TEM-1,beta-lactamase_156,P62593,0.303089,NO,136,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.232,-3.77,2.538,,,H,A,0.55,-0.34,1.04,,48.95,HHH,-1.088,0.111618,0.00442304,0.303089 beta-lactamase_156_N130H,beta-lactamase_156_130,TEM-1,beta-lactamase_156,P62593,0.303129,NO,130,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-0.798,-4.005,3.207,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.111618,0.000683376,0.303129 kka2_1:4_W91E,kka2_1:4_91,Kka2,kka2_1:4,P00552,0.303168,NO,91,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-1.178,-3.842,2.664,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.168804,0.00358653,0.303168 beta-lactamase_156_W288C,beta-lactamase_156_288,TEM-1,beta-lactamase_156,P62593,0.303198,NO,288,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,,,,,,,,,,,,,BHO,,0.111618,,0.303198 beta-lactamase_39_S128A,beta-lactamase_39_128,TEM-1,beta-lactamase_39,P62593,0.303262,NO,128,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-0.84,-2.628,1.788,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.0495842,0.00071483,0.303262 kka2_1:4_V185H,kka2_1:4_185,Kka2,kka2_1:4,P00552,0.303301,NO,185,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.045,-4.98,3.935,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.168804,0.00367031,0.303301 kka2_1:4_R66T,kka2_1:4_66,Kka2,kka2_1:4,P00552,0.303312,NO,66,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-0.922,-3.484,2.562,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.168804,0.00161025,0.303312 beta-lactamase_2500_L191H,beta-lactamase_2500_191,TEM-1,beta-lactamase_2500,P62593,0.303363,NO,191,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.087,-4.898,3.811,,,H,A,0.55,0.09,1.703,,63.29,BHH,-1.445,0.361275,0.00263549,0.303363 kka2_1:2_V49Y,kka2_1:2_49,Kka2,kka2_1:2,P00552,0.303384,NO,49,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.614,-4.126,2.512,,,E,B,0.44,-0.77,1.233,,64.39,HHB,-1.3,0.295029,0.00615685,0.303384 beta-lactamase_625_Y262N,beta-lactamase_625_262,TEM-1,beta-lactamase_625,P62593,0.303403,NO,262,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.213352,0.00853516,0.303403 kka2_1:4_L123H,kka2_1:4_123,Kka2,kka2_1:4,P00552,0.30342,NO,123,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.888,-4.956,4.068,,0.007,H,A,0.55,-0.4,1.447,,48.86,BHB,-1.301,0.168804,0.00325188,0.30342 hsp90_N588E,hsp90_588,hsp90,hsp90,P02829,0.303422,NO,588,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-3.051,-2.818,0,4.61142,0.019,H,A,0.14,0.39,,,,HPH,-3.12167,0.368192,0.000222939,0.303422 kka2_1:1_V198M,kka2_1:1_198,Kka2,kka2_1:1,P00552,0.303429,NO,198,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.719,-3.281,1.562,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.520039,0.00835002,0.303429 beta-lactamase_625_D83W,beta-lactamase_625_83,TEM-1,beta-lactamase_625,P62593,0.303432,NO,83,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.066,-5.509,4.443,,0.354,H,A,0.75,0.22,0.239,,48.95,HAH,-1.34733,0.213352,0.00205968,0.303432 kka2_1:2_K138D,kka2_1:2_138,Kka2,kka2_1:2,P00552,0.303444,NO,138,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-2.5,-2.178,-0.322,,0.594,H,A,2.34,0.98,21.038,21.038,71.59,HBB,-2.48833,0.295029,0.00628542,0.303444 kka2_1:1_D90E,kka2_1:1_90,Kka2,kka2_1:1,P00552,0.303519,NO,90,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.459,-2.578,0.119,,0.104,E,B,0.75,0.73,6.085,,64.39,BAH,-1.72833,0.520039,0.00583842,0.303519 hsp90_A587W,hsp90_587,hsp90,hsp90,P02829,0.303544,NO,587,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.456,-4.251,0,4.91216,0.049,H,A,0.55,-0.02,,,,PHP,-2.757,0.368192,0.000222939,0.303544 beta-lactamase_2500_R220I,beta-lactamase_2500_220,TEM-1,beta-lactamase_2500,P62593,0.303566,NO,220,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-0.942,-3.974,3.032,,0.295,I,A,1.2,-0.76,2.175,,74.48,HBP,-1.33633,0.361275,0.00232421,0.303566 beta-lactamase_2500_S241W,beta-lactamase_2500_241,TEM-1,beta-lactamase_2500,P62593,0.30359,NO,241,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.361275,0.00452736,0.30359 beta-lactamase_625_T179E,beta-lactamase_625_179,TEM-1,beta-lactamase_625,P62593,0.303601,NO,179,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.085,-3.446,2.361,,,E,B,0.22,-1.38,0.367,,73.08,PPH,-1.557,0.213352,0.00226045,0.303601 kka2_1:1_V97N,kka2_1:1_97,Kka2,kka2_1:1,P00552,0.303602,NO,97,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.453,-4.261,2.808,,0.083,,B,1.48,-0.83,13.576,13.576,53.03,AHO,-1.85067,0.520039,0.00737869,0.303602 kka2_1:1_Q163N,kka2_1:1_163,Kka2,kka2_1:1,P00552,0.303651,NO,163,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.162,-3.939,1.777,,0.58,T,B,0.64,1.85,2.779,,64.02,BPO,-1.78333,0.520039,0.00719507,0.303651 hsp90_S586L,hsp90_586,hsp90,hsp90,P02829,0.303667,NO,586,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.764,-2.511,0,4.65438,,,B,0.93,0.15,,,,HPH,-3.157,0.368192,0.000222939,0.303667 kka2_1:8_I228H,kka2_1:8_228,Kka2,kka2_1:8,P00552,0.303673,NO,228,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.142,-5.006,3.864,,,H,A,1.52,-1.2,1.521,,71.59,AHH,-1.54633,0.100394,0.00458834,0.303673 kka2_1:8_I228H,kka2_1:8_228,Kka2,kka2_1:8,P00552,0.303673,NO,228,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.142,-5.006,3.864,,,H,A,1.52,-1.2,1.521,,71.59,AHH,-1.54633,0.100394,0.00458834,0.303673 kka2_1:1_C131W,kka2_1:1_131,Kka2,kka2_1:1,P00552,0.303691,NO,131,C,W,CW,Special,Hydrophobic,5.07,5.89,0.82,215,121,204,83,108.5,227.8,119.3,-0.831,-5.126,4.295,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.520039,0.00170814,0.303691 beta-lactamase_2500_A132H,beta-lactamase_2500_132,TEM-1,beta-lactamase_2500,P62593,0.303723,NO,132,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.9,-4.724,3.824,,,H,A,0.46,-0.93,8.408,,64.69,PHH,-1.138,0.361275,0.000962524,0.303723 kka2_1:4_V113Y,kka2_1:4_113,Kka2,kka2_1:4,P00552,0.303746,NO,113,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.233,-4.11,2.877,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.168804,0.00650191,0.303746 kka2_1:8_D216Q,kka2_1:8_216,Kka2,kka2_1:8,P00552,0.303765,NO,216,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.785,-3.726,2.941,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.100394,0.00229969,0.303765 kka2_1:8_D216Q,kka2_1:8_216,Kka2,kka2_1:8,P00552,0.303765,NO,216,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.785,-3.726,2.941,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.100394,0.00229969,0.303765 kka2_1:1_V214C,kka2_1:1_214,Kka2,kka2_1:1,P00552,0.303798,NO,214,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.261,-3.243,1.982,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.520039,0.00692782,0.303798 kka2_1:1_K138V,kka2_1:1_138,Kka2,kka2_1:1,P00552,0.303804,NO,138,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-2.5,-3.083,0.583,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.520039,0.00628542,0.303804 kka2_1:2_F263W,kka2_1:2_263,Kka2,kka2_1:2,P00552,0.303824,NO,263,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-0.911,-4.558,3.647,,0.006,G,A,1.62,-0.12,5.275,,45.83,AHH,-0.92,0.295029,0.0172454,0.303824 kka2_1:1_C31N,kka2_1:1_31,Kka2,kka2_1:1,P00552,0.303863,NO,31,C,N,CN,Special,Polar,5.07,5.47157,0.401575,139,121,132,11,108.5,114.1,5.6,-2.246,-3.833,1.587,,1.152,S,b,0.46,4.16,8.272,,63.26,OOP,-1.21533,0.520039,0.00681582,0.303863 kka2_1:1_R226E,kka2_1:1_226,Kka2,kka2_1:1,P00552,0.303989,NO,226,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.392,-3.484,2.092,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.520039,0.0108032,0.303989 beta-lactamase_39_Y44P,beta-lactamase_39_44,TEM-1,beta-lactamase_39,P62593,0.304026,NO,44,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-2.547,-4.12,1.573,,,E,B,0.21,-0.45,2.683,,73.78,OHH,-1.86267,0.0495842,0.00426364,0.304026 kka2_1:8_E262M,kka2_1:8_262,Kka2,kka2_1:8,P00552,0.304039,NO,262,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-0.829,-4.701,3.872,,0.059,G,A,1.52,-0.18,0.837,,42.42,AAH,-0.816,0.100394,0.0191586,0.304039 kka2_1:8_E262M,kka2_1:8_262,Kka2,kka2_1:8,P00552,0.304039,NO,262,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-0.829,-4.701,3.872,,0.059,G,A,1.52,-0.18,0.837,,42.42,AAH,-0.816,0.100394,0.0191586,0.304039 beta-lactamase_156_A124W,beta-lactamase_156_124,TEM-1,beta-lactamase_156,P62593,0.304071,NO,124,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.181,-5.322,4.141,,,H,A,0.46,-0.9,2.027,,64.34,HHH,-1.152,0.111618,0.00481399,0.304071 beta-lactamase_625_N168K,beta-lactamase_625_168,TEM-1,beta-lactamase_625,P62593,0.304131,NO,168,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-1.029,-3.307,2.278,,0.113,G,A,0.61,-0.4,1.014,,44.41,HPA,-1.13233,0.213352,0.00288667,0.304131 beta-lactamase_625_L120N,beta-lactamase_625_120,TEM-1,beta-lactamase_625,P62593,0.304176,NO,120,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.044,-4.027,2.983,,,H,A,0.55,-1.13,7.813,,64.69,AHO,-1.13633,0.213352,0.00143563,0.304176 beta-lactamase_156_I125G,beta-lactamase_156_125,TEM-1,beta-lactamase_156,P62593,0.304223,NO,125,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.441,-3.768,2.327,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.111618,0.00383964,0.304223 beta-lactamase_F13E,beta-lactamase_13,TEM-1,beta-lactamase,P62593,0.304237,NO,13,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-2.394,-3.69,1.296,,,,,,,4.079,,77.62,OHH,-2.382,0.221079,0.0029078,0.304237 kka2_1:2_A34L,kka2_1:2_34,Kka2,kka2_1:2,P00552,0.304245,NO,34,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.928,-3.244,2.316,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.295029,0.00343484,0.304245 kka2_1:1_G21T,kka2_1:1_21,Kka2,kka2_1:1,P00552,0.304275,NO,21,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.368,-3.639,2.271,,0.586,T,l,0.29,-0.75,10.291,10.291,71.59,HOH,-2.10167,0.520039,0.00709648,0.304275 kka2_1:2_A41I,kka2_1:2_41,Kka2,kka2_1:2,P00552,0.304285,NO,41,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.879,-3.958,2.079,,0.184,.,B,0.46,-0.96,24.451,24.451,64.39,PHP,-2.477,0.295029,0.00543332,0.304285 kka2_1:2_A191W,kka2_1:2_191,Kka2,kka2_1:2,P00552,0.304396,NO,191,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.831,-5.414,4.583,,,.,b,0.46,-0.94,2.046,,50,AHO,-0.868667,0.295029,0.00338807,0.304396 kka2_1:2_L174H,kka2_1:2_174,Kka2,kka2_1:2,P00552,0.304455,NO,174,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.952,-4.968,4.016,,,H,A,1.59,-0.31,8.521,,51.89,BHB,-2.08533,0.295029,0.00438501,0.304455 beta-lactamase_625_I245Y,beta-lactamase_625_245,TEM-1,beta-lactamase_625,P62593,0.304492,NO,245,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.213352,0.00391032,0.304492 kka2_1:2_S32P,kka2_1:2_32,Kka2,kka2_1:2,P00552,0.304542,NO,32,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-0.804,-3.683,2.879,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.295029,0.00149998,0.304542 beta-lactamase_Y44T,beta-lactamase_44,TEM-1,beta-lactamase,P62593,0.304629,NO,44,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-2.547,-2.836,0.289,5.6273,,E,B,2.55,-0.45,2.683,,73.78,OHH,-1.86267,0.221079,0.00426364,0.304629 beta-lactamase_2500_T178V,beta-lactamase_2500_178,TEM-1,beta-lactamase_2500,P62593,0.304639,NO,178,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-0.791,-3.079,2.288,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.361275,0.000684366,0.304639 kka2_1:1_R258P,kka2_1:1_258,Kka2,kka2_1:1,P00552,0.304692,NO,258,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.626,-4.055,2.429,,0.316,H,A,1.2,-0.85,7.485,7.485,53.03,HBH,-1.25933,0.520039,0.00983174,0.304692 hsp90_S586P,hsp90_586,hsp90,hsp90,P02829,0.30478,NO,586,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.764,-3.033,0,4.65438,,,B,0.93,0.15,,,,HPH,-3.157,0.368192,0.000222939,0.30478 beta-lactamase_2500_M209W,beta-lactamase_2500_209,TEM-1,beta-lactamase_2500,P62593,0.304784,NO,209,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.442,-4.979,3.537,,,H,A,0.55,-0.97,3.229,,64.69,HHA,-1.52633,0.361275,0.00625021,0.304784 kka2_1:2_R217D,kka2_1:2_217,Kka2,kka2_1:2,P00552,0.304807,NO,217,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.158,-3.819,2.661,,0.252,T,A,1.2,-0.59,0.381,,52.27,ABH,-1.127,0.295029,0.0047191,0.304807 kka2_1:2_R217F,kka2_1:2_217,Kka2,kka2_1:2,P00552,0.304807,NO,217,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.158,-4.264,3.106,,0.252,T,A,1.2,-0.59,0.381,,52.27,ABH,-1.127,0.295029,0.0047191,0.304807 kka2_1:4_L174N,kka2_1:4_174,Kka2,kka2_1:4,P00552,0.304903,NO,174,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.952,-4.185,3.233,,,H,A,0.55,-0.31,1.339,,51.89,BHB,-2.08533,0.168804,0.00438501,0.304903 kka2_1:1_A117M,kka2_1:1_117,Kka2,kka2_1:1,P00552,0.30491,NO,117,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.828,-4.464,3.636,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.520039,0.00282984,0.30491 beta-lactamase_2500_T116H,beta-lactamase_2500_116,TEM-1,beta-lactamase_2500,P62593,0.304918,NO,116,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.28,-4.615,3.335,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.361275,0.00336175,0.304918 kka2_1:2_H106I,kka2_1:2_106,Kka2,kka2_1:2,P00552,0.304919,NO,106,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-3.13,-4.034,0.904,,1.065,.,a,0.17,-0.95,2.53,,71.59,PBH,-2.10433,0.295029,0.00730778,0.304919 kka2_1:4_C131N,kka2_1:4_131,Kka2,kka2_1:4,P00552,0.304937,NO,131,C,N,CN,Special,Polar,5.07,5.47157,0.401575,139,121,132,11,108.5,114.1,5.6,-0.831,-4.151,3.32,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.168804,0.00170814,0.304937 beta-lactamase_Q203P,beta-lactamase_203,TEM-1,beta-lactamase,P62593,0.304961,NO,203,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.168,-3.941,1.773,5.65296,0.47,H,A,0.12,-0.38,1.66,,65.38,BPP,-1.614,0.221079,0.00631514,0.304961 kka2_1:1_E169W,kka2_1:1_169,Kka2,kka2_1:1,P00552,0.304963,NO,169,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.996,-5.529,3.533,,0.422,H,A,1.04,0.3,7.546,7.546,65.53,HAH,-1.755,0.520039,0.00730086,0.304963 beta-lactamase_156_A124D,beta-lactamase_156_124,TEM-1,beta-lactamase_156,P62593,0.304972,NO,124,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.181,-3.709,2.528,,,H,A,0.46,-0.9,2.027,,64.34,HHH,-1.152,0.111618,0.00481399,0.304972 PSD95pdz3_D357R,PSD95pdz3_357,PSD95pdz3,PSD95pdz3,P31016,0.304977,NO,357,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.264,-3.615,2.351,5.22306,,,,,10.975,,,,OAP,-1.32367,0.0758425,0.000609015,0.304977 beta-lactamase_156_S128V,beta-lactamase_156_128,TEM-1,beta-lactamase_156,P62593,0.305029,NO,128,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-0.84,-3.529,2.689,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.111618,0.00071483,0.305029 kka2_1:2_C192L,kka2_1:2_192,Kka2,kka2_1:2,P00552,0.305041,NO,192,C,L,CL,Special,Hydrophobic,5.07,9.7088,4.6388,198,121,131,10,108.5,166.7,58.2,-1.067,-3.26,2.193,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.295029,0.00485428,0.305041 beta-lactamase_I278A,beta-lactamase_278,TEM-1,beta-lactamase,P62593,0.305045,NO,278,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.348,-3.123,1.775,5.35127,0.015,H,A,0.77,-0.85,2.718,,63.29,AHO,-1.41833,0.221079,0.0310297,0.305045 beta-lactamase_39_D129H,beta-lactamase_39_129,TEM-1,beta-lactamase_39,P62593,0.305076,NO,129,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.816,-4.453,3.637,,,,B,0.75,-0.69,0.56,,34.97,PAP,-0.818,0.0495842,0.00109178,0.305076 beta-lactamase_2500_E87R,beta-lactamase_2500_87,TEM-1,beta-lactamase_2500,P62593,0.305157,NO,87,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.421,-3.739,2.318,,0.048,,B,1.04,0.92,17.923,17.923,64.69,PAP,-1.969,0.361275,0.00337888,0.305157 beta-lactamase_2500_A246F,beta-lactamase_2500_246,TEM-1,beta-lactamase_2500,P62593,0.305195,NO,246,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.121,-2.727,0.606,,0.01,E,B,0.46,-1.01,0.753,,73.78,HHH,-1.55633,0.361275,0.00569458,0.305195 beta-lactamase_625_A124Y,beta-lactamase_625_124,TEM-1,beta-lactamase_625,P62593,0.305216,NO,124,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.181,-4.228,3.047,,,H,A,0.46,-0.9,2.027,,64.34,HHH,-1.152,0.213352,0.00481399,0.305216 kka2_1:2_D183W,kka2_1:2_183,Kka2,kka2_1:2,P00552,0.30523,NO,183,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.204,-5.594,4.39,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.295029,0.00426304,0.30523 kka2_1:2_L259D,kka2_1:2_259,Kka2,kka2_1:2,P00552,0.305251,NO,259,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.088,-4.066,2.978,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.295029,0.0206964,0.305251 beta-lactamase_625_V72N,beta-lactamase_625_72,TEM-1,beta-lactamase_625,P62593,0.305345,NO,72,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.658,-4.143,2.485,,,H,A,0.44,-1.03,0.981,,65.73,BHH,-1.32167,0.213352,0.00501194,0.305345 PSD95pdz3_A376D,PSD95pdz3_376,PSD95pdz3,PSD95pdz3,P31016,0.305351,NO,376,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.307,-3.375,2.068,4.72134,,,,,17.108,,,,HHH,-1.49567,0.0758425,0.000341232,0.305351 beta-lactamase_2500_I258D,beta-lactamase_2500_258,TEM-1,beta-lactamase_2500,P62593,0.305381,NO,258,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.361275,0.007931,0.305381 kka2_1:4_F263H,kka2_1:4_263,Kka2,kka2_1:4,P00552,0.305414,NO,263,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-0.911,-4.571,3.66,,0.006,G,A,0.58,-0.12,2.284,,45.83,AHH,-0.92,0.168804,0.0172454,0.305414 kka2_1:1_E230N,kka2_1:1_230,Kka2,kka2_1:1,P00552,0.305426,NO,230,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.672,-3.821,1.149,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.520039,0.00920051,0.305426 kka2_1:1_E262I,kka2_1:1_262,Kka2,kka2_1:1,P00552,0.305426,NO,262,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-0.829,-4.062,3.233,,0.059,G,A,1.04,-0.18,0.837,,42.42,AAH,-0.816,0.520039,0.0191586,0.305426 kka2_1:1_Y244P,kka2_1:1_244,Kka2,kka2_1:1,P00552,0.305503,NO,244,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-0.775,-4.133,3.358,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.520039,0.00453187,0.305503 beta-lactamase_2500_F64L,beta-lactamase_2500_64,TEM-1,beta-lactamase_2500,P62593,0.305525,NO,64,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-0.841,-2.908,2.067,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.361275,0.000947691,0.305525 kka2_1:2_S204W,kka2_1:2_204,Kka2,kka2_1:2,P00552,0.305601,NO,204,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.353,-5.392,4.039,,0.144,E,A,0.27,-1.2,2.442,,65.53,HPO,-0.953333,0.295029,0.00881794,0.305601 WW_domain_T197R,WW_domain_197,Yap65,WW_domain,P46937,0.305626,NO,197,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.575,-3.694,2.119,6.59907,,,,,,21.052,21.052,70.04,PPP,-1.60267,0.153962,0.00319242,0.305626 kka2_1:2_Y218G,kka2_1:2_218,Kka2,kka2_1:2,P00552,0.305667,NO,218,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-1.438,-3.625,2.187,,0.122,H,A,0.21,-0.69,1.022,,56.06,BHP,-1.17533,0.295029,0.0126098,0.305667 kka2_1:2_I207A,kka2_1:2_207,Kka2,kka2_1:2,P00552,0.305721,NO,207,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.175,-3.122,1.947,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.295029,0.00611824,0.305721 beta-lactamase_156_T107Q,beta-lactamase_156_107,TEM-1,beta-lactamase_156,P62593,0.305741,NO,107,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.117,-3.889,2.772,,,G,A,0.22,-0.06,0.341,,67.83,HPA,-1.265,0.111618,0.00239347,0.305741 kka2_1:1_A255W,kka2_1:1_255,Kka2,kka2_1:1,P00552,0.305761,NO,255,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.715,-5.451,3.736,,0.466,H,A,0.46,-0.52,0.946,,65.53,HHH,-1.71267,0.520039,0.0126809,0.305761 kka2_1:1_A41I,kka2_1:1_41,Kka2,kka2_1:1,P00552,0.305772,NO,41,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.879,-3.958,2.079,,0.184,.,B,0.46,-0.96,18.207,18.207,64.39,PHP,-2.477,0.520039,0.00543332,0.305772 kka2_1:1_L94C,kka2_1:1_94,Kka2,kka2_1:1,P00552,0.305799,NO,94,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.618,-4.788,3.17,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.520039,0.00520888,0.305799 kka2_1:4_L193G,kka2_1:4_193,Kka2,kka2_1:4,P00552,0.305832,NO,193,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.983,-3.8,2.817,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.168804,0.00480179,0.305832 kka2_1:1_N195C,kka2_1:1_195,Kka2,kka2_1:1,P00552,0.305863,NO,195,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-0.836,-5.139,4.303,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.520039,0.00276134,0.305863 beta-lactamase_2500_P224I,beta-lactamase_2500_224,TEM-1,beta-lactamase_2500,P62593,0.305918,NO,224,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.893,-4.034,3.141,,0.383,,B,0.52,-0.3,2.666,,74.48,HOH,-1.26433,0.361275,0.00189564,0.305918 beta-lactamase_2500_G240W,beta-lactamase_2500_240,TEM-1,beta-lactamase_2500,P62593,0.305989,NO,240,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.361275,0.00591201,0.305989 kka2_1:1_D208K,kka2_1:1_208,Kka2,kka2_1:1,P00552,0.306096,NO,208,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.708,-3.485,2.777,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.520039,0.00212588,0.306096 kka2_1:1_G205F,kka2_1:1_205,Kka2,kka2_1:1,P00552,0.306152,NO,205,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.596,-4.32,3.724,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.520039,0.00221855,0.306152 kka2_1:2_K50D,kka2_1:2_50,Kka2,kka2_1:2,P00552,0.306173,NO,50,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-0.833,-3.541,2.708,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.295029,0.00138626,0.306173 beta-lactamase_156_L188K,beta-lactamase_156_188,TEM-1,beta-lactamase_156,P62593,0.306176,NO,188,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.166,-3.695,2.529,,,H,A,0.55,-0.3,1.574,,60.14,PHB,-1.47033,0.111618,0.00295687,0.306176 kka2_1:4_L70I,kka2_1:4_70,Kka2,kka2_1:4,P00552,0.3062,NO,70,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.017,-2.539,1.522,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.168804,0.00411884,0.3062 kka2_1:4_R140D,kka2_1:4_140,Kka2,kka2_1:4,P00552,0.306204,NO,140,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.351,-3.692,2.341,,0.12,H,A,1.2,0.2,2.561,,53.03,BBH,-1.885,0.168804,0.00430167,0.306204 kka2_1:1_S104A,kka2_1:1_104,Kka2,kka2_1:1,P00552,0.306236,NO,104,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.436,-3.053,1.617,,0.536,T,A,0.27,-1.11,5.49,,63.64,HPP,-1.91433,0.520039,0.00555207,0.306236 beta-lactamase_625_I285D,beta-lactamase_625_285,TEM-1,beta-lactamase_625,P62593,0.306255,NO,285,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.213352,0.101555,0.306255 kka2_1:1_R38T,kka2_1:1_38,Kka2,kka2_1:1,P00552,0.30627,NO,38,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.207,-3.514,2.307,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.520039,0.00372499,0.30627 beta-lactamase_2500_T178E,beta-lactamase_2500_178,TEM-1,beta-lactamase_2500,P62593,0.306357,NO,178,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-0.791,-3.44,2.649,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.361275,0.000684366,0.306357 kka2_1:1_M148K,kka2_1:1_148,Kka2,kka2_1:1,P00552,0.306389,NO,148,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.847,-3.762,1.915,,0.268,H,A,1.59,0.71,4.618,,64.39,BHA,-1.65467,0.520039,0.00982664,0.306389 kka2_1:4_F264P,kka2_1:4_264,Kka2,kka2_1:4,P00552,0.306391,NO,264,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.02,-4.363,3.343,,0.296,,?,1.62,0.02,1.93,,71.59,HHO,-0.9655,0.168804,,0.306391 Ubiquitin_G10T,Ubiquitin_10,Uba1,Ubiquitin,P0CG48,0.306452,NO,10,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.396,-3.545,2.149,5.29806,0.115,S,l,,0.2,,,,POB,-1.38633,0.205827,0.000748953,0.306452 Ubiquitin_G75F,Ubiquitin_75,Uba1,Ubiquitin,P0CG48,0.306452,NO,75,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.613,-3.108,1.495,5.44099,0.552,T,A,0.73,0.9,4.017,,34.31,BOO,-1.66767,0.205827,0.000712673,0.306452 Ubiquitin_G76C,Ubiquitin_76,Uba1,Ubiquitin,P0CG48,0.306452,NO,76,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.651,-5.088,3.437,5.7647,0.23,,B,0.12,0.08,9.665,9.665,34.31,OOO,-1.632,0.205827,0.000653872,0.306452 Ubiquitin_K48G,Ubiquitin_48,Uba1,Ubiquitin,P0CG48,0.306452,NO,48,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.436,-3.426,1.99,5.03072,0.132,E,B,2.92,-0.28,1.539,,53.87,OBP,-1.6,0.205827,0.000394633,0.306452 Ubiquitin_L43W,Ubiquitin_43,Uba1,Ubiquitin,P0CG48,0.306452,NO,43,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.269,-5.236,3.967,4.8799,,E,B,1.75,-1.17,10.246,10.246,53.87,BHH,-1.46867,0.205827,0.000572481,0.306452 Ubiquitin_Q41R,Ubiquitin_41,Uba1,Ubiquitin,P0CG48,0.306452,NO,41,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-1.329,-3.477,2.148,4.9201,0.017,E,B,0.12,-0.98,0.812,,30.07,PPB,-1.55067,0.205827,0.000521668,0.306452 Ubiquitin_R42T,Ubiquitin_42,Uba1,Ubiquitin,P0CG48,0.306452,NO,42,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.571,-3.513,1.942,5.07805,0.244,E,B,0.68,-0.54,1.976,,72.85,PBH,-1.38967,0.205827,0.000622265,0.306452 hsp90_S586V,hsp90_586,hsp90,hsp90,P02829,0.306454,NO,586,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.764,-2.682,0,4.65438,,,B,0.93,0.15,,,,HPH,-3.157,0.368192,0.000222939,0.306454 kka2_1:1_I254C,kka2_1:1_254,Kka2,kka2_1:1,P00552,0.306467,NO,254,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.933,-4.856,2.923,,0.135,H,A,1.52,-0.6,1.859,,71.59,BHH,-1.668,0.520039,0.0132375,0.306467 PSD95pdz3_Q358P,PSD95pdz3_358,PSD95pdz3,PSD95pdz3,P31016,0.306473,NO,358,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-1.699,-3.336,1.637,5.21282,,,,,14.8844,,,,APH,-1.531,0.0758425,0.000594893,0.306473 kka2_1:1_R211E,kka2_1:1_211,Kka2,kka2_1:1,P00552,0.306496,NO,211,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-0.899,-3.317,2.418,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.520039,0.00204888,0.306496 kka2_1:1_R211Y,kka2_1:1_211,Kka2,kka2_1:1,P00552,0.306496,NO,211,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-0.899,-4.076,3.177,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.520039,0.00204888,0.306496 beta-lactamase_0_L197M,beta-lactamase_0_197,TEM-1,beta-lactamase_0,P62593,0.306505,NO,197,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.853,-3.888,3.035,,0.007,S,B,0.55,0.33,1.087,,60.14,HHP,-1.833,0.0500837,0.00144602,0.306505 kka2_1:4_F264T,kka2_1:4_264,Kka2,kka2_1:4,P00552,0.306517,NO,264,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.02,-3.729,2.709,,0.296,,?,1.62,0.02,1.93,,71.59,HHO,-0.9655,0.168804,,0.306517 kka2_1:2_I207G,kka2_1:2_207,Kka2,kka2_1:2,P00552,0.306527,NO,207,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.175,-3.853,2.678,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.295029,0.00611824,0.306527 kka2_1:1_S204C,kka2_1:1_204,Kka2,kka2_1:1,P00552,0.306591,NO,204,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.353,-4.762,3.409,,0.144,E,A,0.27,-1.2,3.022,,65.53,HPO,-0.953333,0.520039,0.00881794,0.306591 kka2_1:4_W24E,kka2_1:4_24,Kka2,kka2_1:4,P00552,0.306632,NO,24,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-1.779,-4.036,2.257,,0.477,E,B,1.51,-0.21,2.666,,56.06,AHH,-2.24467,0.168804,0.00631564,0.306632 kka2_1:1_C192M,kka2_1:1_192,Kka2,kka2_1:1,P00552,0.306688,NO,192,C,M,CM,Special,Hydrophobic,5.07,5.74,0.67,196,121,149,28,108.5,162.9,54.4,-1.067,-4.582,3.515,,0.095,.,B,0.46,-0.75,2.749,,50,HOH,-0.960333,0.520039,0.00485428,0.306688 beta-lactamase_L160E,beta-lactamase_160,TEM-1,beta-lactamase,P62593,0.306702,NO,160,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.977,-3.906,2.929,5.32068,0.022,,B,1.75,-0.6,0.895,,44.41,BHA,-0.936,0.221079,0.00193775,0.306702 beta-lactamase_2500_F58G,beta-lactamase_2500_58,TEM-1,beta-lactamase_2500,P62593,0.306707,NO,58,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-2.914,-3.566,0.652,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.361275,0.00523369,0.306707 kka2_1:1_S11N,kka2_1:1_11,Kka2,kka2_1:1,P00552,0.306722,NO,11,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.322,-3.885,1.563,,0.408,,B,0.77,1.64,2.054,,92.05,OPO,-1.69867,0.520039,0.00381691,0.306722 kka2_1:1_R18Q,kka2_1:1_18,Kka2,kka2_1:1,P00552,0.30675,NO,18,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.055,-2.59,0.535,,0.474,T,A,1.2,0.54,11.422,11.422,71.59,ABH,-1.821,0.520039,0.00724065,0.30675 kka2_1:1_P98S,kka2_1:1_98,Kka2,kka2_1:1,P00552,0.306757,NO,98,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.526,-2.565,1.039,,0.391,S,B,0.52,-0.65,1.521,,63.26,HOO,-1.19167,0.520039,0.00622754,0.306757 beta-lactamase_2500_G76D,beta-lactamase_2500_76,TEM-1,beta-lactamase_2500,P62593,0.306775,NO,76,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.189,-3.614,2.425,,,H,A,0.29,-0.67,1.012,,67.83,OOH,-1.22267,0.361275,0.00476637,0.306775 beta-lactamase_2500_A40Y,beta-lactamase_2500_40,TEM-1,beta-lactamase_2500,P62593,0.306779,NO,40,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.402,-4.322,2.92,,0.155,S,B,0.46,0.21,0.953,,73.78,OHB,-1.40267,0.361275,0.00490026,0.306779 WW_domain_W177G,WW_domain_177,Yap65,WW_domain,P46937,0.306795,NO,177,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-1.198,-3.135,1.937,5.18137,,,,,,,,,OHA,-1.197,0.153962,0.00198549,0.306795 kka2_1:1_D134V,kka2_1:1_134,Kka2,kka2_1:1,P00552,0.306812,NO,134,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.969,-3.724,2.755,,0.421,B,B,0.75,0.31,2.329,,49.62,HAB,-1.057,0.520039,0.00270812,0.306812 kka2_1:2_R121W,kka2_1:2_121,Kka2,kka2_1:2,P00552,0.306826,NO,121,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.552,-5.451,3.899,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.295029,0.00523326,0.306826 kka2_1:1_A117G,kka2_1:1_117,Kka2,kka2_1:1,P00552,0.306859,NO,117,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.828,-3.044,2.216,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.520039,0.00282984,0.306859 kka2_1:1_T51K,kka2_1:1_51,Kka2,kka2_1:1,P00552,0.306884,NO,51,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.199,-3.076,0.877,,0.05,E,B,0.22,-0.05,3.056,,63.64,BPA,-1.76767,0.520039,0.00628861,0.306884 kka2_1:2_R143E,kka2_1:2_143,Kka2,kka2_1:2,P00552,0.306892,NO,143,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.525,-2.41,-0.115,,0.325,H,A,0.16,1.22,14.853,14.853,65.53,ABH,-1.86833,0.295029,0.00662247,0.306892 beta-lactamase_39_C75E,beta-lactamase_39_75,TEM-1,beta-lactamase_39,P62593,0.306916,NO,75,C,E,CE,Special,negativeCharge,5.07,3.22,-1.85,170,121,147,26,108.5,138.4,29.9,-1.245,-3.874,2.629,,,H,A,0.46,-0.87,2.369,,50,HOO,-1.24333,0.0495842,0.0034616,0.306916 kka2_1:4_V49Q,kka2_1:4_49,Kka2,kka2_1:4,P00552,0.307002,NO,49,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.614,-4.261,2.647,,,E,B,0.44,-0.77,1.233,,64.39,HHB,-1.3,0.168804,0.00615685,0.307002 kka2_1:2_C131S,kka2_1:2_131,Kka2,kka2_1:2,P00552,0.307128,NO,131,C,S,CS,Special,Polar,5.07,5.68,0.61,112,121,105,-16,108.5,89,-19.5,-0.831,-3.414,2.583,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.295029,0.00170814,0.307128 beta-lactamase_2500_K232E,beta-lactamase_2500_232,TEM-1,beta-lactamase_2500,P62593,0.307138,NO,232,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.012,-3.087,2.075,,,E,B,2.34,-1.1,3.048,,65.03,ABP,-1.238,0.361275,0.00313441,0.307138 kka2_1:8_G189P,kka2_1:8_189,Kka2,kka2_1:8,P00552,0.307171,NO,189,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.596,-3.908,3.312,,0.034,S,l,0.75,-0.99,,,,BOA,-0.739,0.100394,0.00253688,0.307171 kka2_1:8_G189P,kka2_1:8_189,Kka2,kka2_1:8,P00552,0.307171,NO,189,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.596,-3.908,3.312,,0.034,S,l,0.75,-0.99,,,,BOA,-0.739,0.100394,0.00253688,0.307171 kka2_1:8_G201P,kka2_1:8_201,Kka2,kka2_1:8,P00552,0.307171,NO,201,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.56,-3.175,1.615,,0.149,T,l,0.75,-0.57,2.152,,52.65,POB,-1.92233,0.100394,0.00820117,0.307171 kka2_1:8_G201P,kka2_1:8_201,Kka2,kka2_1:8,P00552,0.307171,NO,201,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.56,-3.175,1.615,,0.149,T,l,0.75,-0.57,2.152,,52.65,POB,-1.92233,0.100394,0.00820117,0.307171 beta-lactamase_S240R,beta-lactamase_240,TEM-1,beta-lactamase,P62593,0.307267,NO,240,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.537,-3.823,2.286,4.75024,,,B,0.74,-0.74,0.357,,65.38,OPB,-1.263,0.221079,0.00591201,0.307267 kka2_1:2_E182I,kka2_1:2_182,Kka2,kka2_1:2,P00552,0.3073,NO,182,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.516,-4.087,2.571,,0.326,,B,1.52,0.75,14.547,14.547,65.53,OAA,-1.806,0.295029,0.00641548,0.3073 kka2_1:2_V97W,kka2_1:2_97,Kka2,kka2_1:2,P00552,0.307324,NO,97,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.453,-5.36,3.907,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.295029,0.00737869,0.307324 beta-lactamase_2500_D48I,beta-lactamase_2500_48,TEM-1,beta-lactamase_2500,P62593,0.307342,NO,48,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.101,-4.047,2.946,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.361275,0.0027273,0.307342 kka2_1:1_C209Q,kka2_1:1_209,Kka2,kka2_1:1,P00552,0.307357,NO,209,C,Q,CQ,Special,Polar,5.07,6.24429,1.17429,154,121,146,25,108.5,143.8,35.3,-0.906,-4.376,3.47,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.520039,0.00260862,0.307357 beta-lactamase_2500_G281E,beta-lactamase_2500_281,TEM-1,beta-lactamase_2500,P62593,0.307402,NO,281,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.361275,0.0406482,0.307402 kka2_1:4_C192R,kka2_1:4_192,Kka2,kka2_1:4,P00552,0.30741,NO,192,C,R,CR,Special,PositiveCharge,5.07,6.34148,1.27148,180,121,174,53,108.5,173.4,64.9,-1.067,-4.134,3.067,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.168804,0.00485428,0.30741 beta-lactamase_625_N134H,beta-lactamase_625_134,TEM-1,beta-lactamase_625,P62593,0.307504,NO,134,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-0.879,-4.073,3.194,,0.138,H,A,0.61,-0.6,3.776,,53.15,HPH,-1.02233,0.213352,0.000644786,0.307504 kka2_1:4_K50L,kka2_1:4_50,Kka2,kka2_1:4,P00552,0.307507,NO,50,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-0.833,-3.41,2.577,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.168804,0.00138626,0.307507 kka2_1:1_L193C,kka2_1:1_193,Kka2,kka2_1:1,P00552,0.307553,NO,193,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.983,-4.807,3.824,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.520039,0.00480179,0.307553 beta-lactamase_625_V260F,beta-lactamase_625_260,TEM-1,beta-lactamase_625,P62593,0.307555,NO,260,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.213352,0.00471757,0.307555 beta-lactamase_625_V157P,beta-lactamase_625_157,TEM-1,beta-lactamase_625,P62593,0.307635,NO,157,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.751,-4.03,2.279,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.213352,0.00506849,0.307635 kka2_1:1_A150I,kka2_1:1_150,Kka2,kka2_1:1,P00552,0.30767,NO,150,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.949,-3.788,2.839,,0.544,T,A,0.46,1.34,2.333,,63.26,AHO,-1.272,0.520039,0.0045009,0.30767 kka2_1:1_E160Y,kka2_1:1_160,Kka2,kka2_1:1,P00552,0.30767,NO,160,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.683,-4.448,2.765,,0.989,G,A,1.04,2.28,0.273,,71.59,AAA,-1.36133,0.520039,0.00935762,0.30767 kka2_1:1_D208M,kka2_1:1_208,Kka2,kka2_1:1,P00552,0.307717,NO,208,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.708,-4.958,4.25,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.520039,0.00212588,0.307717 beta-lactamase_625_L223W,beta-lactamase_625_223,TEM-1,beta-lactamase_625,P62593,0.307809,NO,223,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.055,-5.101,4.046,,0.27,,B,0.55,0.09,1.633,,74.48,HHO,-1.35033,0.213352,0.00372793,0.307809 kka2_1:4_M148N,kka2_1:4_148,Kka2,kka2_1:4,P00552,0.307852,NO,148,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.847,-4.17,2.323,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.168804,0.00982664,0.307852 kka2_1:8_V198K,kka2_1:8_198,Kka2,kka2_1:8,P00552,0.307852,NO,198,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.719,-3.652,1.933,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.100394,0.00835002,0.307852 kka2_1:8_V198K,kka2_1:8_198,Kka2,kka2_1:8,P00552,0.307852,NO,198,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.719,-3.652,1.933,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.100394,0.00835002,0.307852 kka2_1:4_L259N,kka2_1:4_259,Kka2,kka2_1:4,P00552,0.307924,NO,259,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.088,-4.082,2.994,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.168804,0.0206964,0.307924 beta-lactamase_2500_G249A,beta-lactamase_2500_249,TEM-1,beta-lactamase_2500,P62593,0.307949,NO,249,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.312,,,,0.256,S,B,0.23,0.04,30.841,30.841,72.73,HOO,-1.81367,0.361275,0.00220169,0.307949 beta-lactamase_39_G76P,beta-lactamase_39_76,TEM-1,beta-lactamase_39,P62593,0.308062,NO,76,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.189,-3.852,2.663,,,H,A,0.29,-0.67,2.145,,67.83,OOH,-1.22267,0.0495842,0.00476637,0.308062 kka2_1:4_D157S,kka2_1:4_157,Kka2,kka2_1:4,P00552,0.308067,NO,157,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.993,-2.619,1.626,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.168804,0.0042313,0.308067 kka2_1:2_Q27Y,kka2_1:2_27,Kka2,kka2_1:2,P00552,0.30815,NO,27,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-1.659,-4.273,2.614,,0.608,.,A,0.64,0.71,0.521,,65.53,PPP,-1.90733,0.295029,0.00595365,0.30815 beta-lactamase_2500_L79H,beta-lactamase_2500_79,TEM-1,beta-lactamase_2500,P62593,0.308151,NO,79,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.842,-4.903,4.061,,0.007,H,A,0.55,-0.16,0.823,,50.35,HHP,-1.44333,0.361275,0.000947397,0.308151 kka2_1:2_E63N,kka2_1:2_63,Kka2,kka2_1:2,P00552,0.308179,NO,63,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-0.762,-3.476,2.714,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.295029,0.00118399,0.308179 kka2_1:1_K112S,kka2_1:1_112,Kka2,kka2_1:1,P00552,0.308185,NO,112,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-2.491,-2.816,0.325,,0.076,H,A,2.34,-1.37,23.433,23.433,56.06,ABH,-2.00133,0.520039,0.00645389,0.308185 kka2_1:1_K50H,kka2_1:1_50,Kka2,kka2_1:1,P00552,0.308206,NO,50,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-0.833,-4.481,3.648,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.520039,0.00138626,0.308206 beta-lactamase_2500_G141I,beta-lactamase_2500_141,TEM-1,beta-lactamase_2500,P62593,0.308264,NO,141,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.828,-4.236,3.408,,0.575,T,l,0.29,-0.28,1.493,,64.69,HOO,-1.08933,0.361275,0.0012419,0.308264 kka2_1:1_A110K,kka2_1:1_110,Kka2,kka2_1:1,P00552,0.308266,NO,110,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.064,-3.119,1.055,,0.175,H,A,1.04,-1.19,11.755,,71.59,OHA,-1.91867,0.520039,0.00759851,0.308266 kka2_1:1_L260T,kka2_1:1_260,Kka2,kka2_1:1,P00552,0.308276,NO,260,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.741,-3.45,2.709,,0.022,H,A,0.55,-0.52,,,,HHA,-0.845667,0.520039,0.0233782,0.308276 kka2_1:1_P109C,kka2_1:1_109,Kka2,kka2_1:1,P00552,0.308281,NO,109,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.412,-5.056,3.644,,0.376,H,A,0.52,-1.25,18.506,18.506,65.53,HOH,-1.84567,0.520039,0.0070929,0.308281 beta-lactamase_156_S68N,beta-lactamase_156_68,TEM-1,beta-lactamase_156,P62593,0.308288,NO,68,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-0.913,-2.44,1.527,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.111618,0.000800065,0.308288 kka2_1:1_L212S,kka2_1:1_212,Kka2,kka2_1:1,P00552,0.308334,NO,212,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.904,-3.574,2.67,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.520039,0.0031426,0.308334 kka2_1:2_A191D,kka2_1:2_191,Kka2,kka2_1:2,P00552,0.308362,NO,191,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.831,-3.72,2.889,,,.,b,0.46,-0.94,2.046,,50,AHO,-0.868667,0.295029,0.00338807,0.308362 kka2_1:8_Y257A,kka2_1:8_257,Kka2,kka2_1:8,P00552,0.308389,NO,257,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-1.064,-3.39,2.326,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.100394,0.0148191,0.308389 kka2_1:8_Y257A,kka2_1:8_257,Kka2,kka2_1:8,P00552,0.308389,NO,257,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-1.064,-3.39,2.326,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.100394,0.0148191,0.308389 kka2_1:1_N195R,kka2_1:1_195,Kka2,kka2_1:1,P00552,0.308393,NO,195,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-0.836,-3.572,2.736,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.520039,0.00276134,0.308393 kka2_1:2_G55E,kka2_1:2_55,Kka2,kka2_1:2,P00552,0.308464,NO,55,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.625,-2.785,1.16,,0.517,S,b,0.75,1.19,15.753,15.753,63.64,POH,-2.05967,0.295029,0.00667877,0.308464 WW_domain_Q195P,WW_domain_195,Yap65,WW_domain,P46937,0.308466,NO,195,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-1.839,-3.691,1.852,5.22735,,,,,,1.803,,70.04,APP,-1.719,0.153962,0.00394344,0.308466 kka2_1:2_I221G,kka2_1:2_221,Kka2,kka2_1:2,P00552,0.308467,NO,221,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.739,-3.884,2.145,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.295029,0.00945908,0.308467 kka2_1:1_A215K,kka2_1:1_215,Kka2,kka2_1:1,P00552,0.308573,NO,215,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.968,-3.512,2.544,,0.039,E,B,0.46,-0.59,0.754,,50.38,HHA,-1.00467,0.520039,0.00529129,0.308573 kka2_1:1_I29Y,kka2_1:1_29,Kka2,kka2_1:1,P00552,0.308615,NO,29,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.692,-4.24,2.548,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.520039,0.00619521,0.308615 beta-lactamase_C121N,beta-lactamase_121,TEM-1,beta-lactamase,P62593,0.308623,NO,121,C,N,CN,Special,Polar,5.07,5.47157,0.401575,139,121,132,11,108.5,114.1,5.6,-0.953,-4.045,3.092,5.12205,,H,A,2.8,-0.81,7.644,,63.29,HOP,-1.46767,0.221079,0.000744322,0.308623 kka2_1:2_R217A,kka2_1:2_217,Kka2,kka2_1:2,P00552,0.308641,NO,217,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.158,-3.215,2.057,,0.252,T,A,1.2,-0.59,0.381,,52.27,ABH,-1.127,0.295029,0.0047191,0.308641 kka2_1:1_L158V,kka2_1:1_158,Kka2,kka2_1:1,P00552,0.308649,NO,158,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.947,-2.604,0.657,,0.095,.,B,0.55,0.77,7.588,,63.64,AHA,-1.25333,0.520039,0.00529068,0.308649 kka2_1:2_H162K,kka2_1:2_162,Kka2,kka2_1:2,P00552,0.308657,NO,162,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-2.319,-3.151,0.832,,0.071,G,A,0.17,1.01,3.187,,64.39,ABP,-2.02067,0.295029,0.00616145,0.308657 kka2_1:8_C192L,kka2_1:8_192,Kka2,kka2_1:8,P00552,0.308659,NO,192,C,L,CL,Special,Hydrophobic,5.07,9.7088,4.6388,198,121,131,10,108.5,166.7,58.2,-1.067,-3.26,2.193,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.100394,0.00485428,0.308659 kka2_1:8_C192L,kka2_1:8_192,Kka2,kka2_1:8,P00552,0.308659,NO,192,C,L,CL,Special,Hydrophobic,5.07,9.7088,4.6388,198,121,131,10,108.5,166.7,58.2,-1.067,-3.26,2.193,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.100394,0.00485428,0.308659 kka2_1:8_F206P,kka2_1:8_206,Kka2,kka2_1:8,P00552,0.308659,NO,206,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.349,-4.311,2.962,,0.006,E,B,1.62,-1.21,1.052,,63.64,OHH,-1.04,0.100394,0.00936868,0.308659 kka2_1:8_F206P,kka2_1:8_206,Kka2,kka2_1:8,P00552,0.308659,NO,206,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.349,-4.311,2.962,,0.006,E,B,1.62,-1.21,1.052,,63.64,OHH,-1.04,0.100394,0.00936868,0.308659 kka2_1:8_G205T,kka2_1:8_205,Kka2,kka2_1:8,P00552,0.308677,NO,205,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.596,-3.675,3.079,,,E,b,0.75,-1.05,,,,POH,-1.09933,0.100394,0.00221855,0.308677 kka2_1:8_G205T,kka2_1:8_205,Kka2,kka2_1:8,P00552,0.308677,NO,205,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.596,-3.675,3.079,,,E,b,0.75,-1.05,,,,POH,-1.09933,0.100394,0.00221855,0.308677 kka2_1:4_E262P,kka2_1:4_262,Kka2,kka2_1:4,P00552,0.308698,NO,262,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-0.829,-3.706,2.877,,0.059,G,A,1.04,-0.18,2.383,,42.42,AAH,-0.816,0.168804,0.0191586,0.308698 kka2_1:4_L19Q,kka2_1:4_19,Kka2,kka2_1:4,P00552,0.308699,NO,19,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.254,-4.298,3.044,,0.08,T,A,1.59,-0.26,2.645,,65.53,BHH,-2.221,0.168804,0.00620703,0.308699 kka2_1:4_A224N,kka2_1:4_224,Kka2,kka2_1:4,P00552,0.308711,NO,224,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.977,-3.898,2.921,,,H,A,0.46,-1.26,0.93,,63.64,HHP,-1.41033,0.168804,0.00352047,0.308711 kka2_1:1_I196E,kka2_1:1_196,Kka2,kka2_1:1,P00552,0.308723,NO,196,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-2.115,-4.03,1.915,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.520039,0.0107273,0.308723 kka2_1:8_C209H,kka2_1:8_209,Kka2,kka2_1:8,P00552,0.308794,NO,209,C,H,CH,Special,PositiveCharge,5.07,7.59,2.52,174,121,155,34,108.5,153.2,44.7,-0.906,-4.957,4.051,,,,a,1.5,-0.89,0.391,,19.32,AOO,-0.903,0.100394,0.00260862,0.308794 kka2_1:8_C209H,kka2_1:8_209,Kka2,kka2_1:8,P00552,0.308794,NO,209,C,H,CH,Special,PositiveCharge,5.07,7.59,2.52,174,121,155,34,108.5,153.2,44.7,-0.906,-4.957,4.051,,,,a,1.5,-0.89,0.391,,19.32,AOO,-0.903,0.100394,0.00260862,0.308794 beta-lactamase_2500_Y95A,beta-lactamase_2500_95,TEM-1,beta-lactamase_2500,P62593,0.308834,NO,95,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-1.715,-3.364,1.649,,0.122,,b,0.21,-0.37,2.914,,77.62,BHP,-2.16167,0.361275,0.00479449,0.308834 kka2_1:1_D183M,kka2_1:1_183,Kka2,kka2_1:1,P00552,0.308838,NO,183,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.204,-4.843,3.639,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.520039,0.00426304,0.308838 kka2_1:1_Q26A,kka2_1:1_26,Kka2,kka2_1:1,P00552,0.308849,NO,26,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.18,-2.361,0.181,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.520039,0.00708962,0.308849 kka2_1:8_F206Q,kka2_1:8_206,Kka2,kka2_1:8,P00552,0.308929,NO,206,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.349,-4.252,2.903,,0.006,E,B,1.62,-1.21,1.052,,63.64,OHH,-1.04,0.100394,0.00936868,0.308929 kka2_1:8_F206Q,kka2_1:8_206,Kka2,kka2_1:8,P00552,0.308929,NO,206,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.349,-4.252,2.903,,0.006,E,B,1.62,-1.21,1.052,,63.64,OHH,-1.04,0.100394,0.00936868,0.308929 beta-lactamase_L120G,beta-lactamase_120,TEM-1,beta-lactamase,P62593,0.30894,NO,120,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.044,-3.788,2.744,5.11974,,H,A,1.3,-1.13,1.988,,64.69,AHO,-1.13633,0.221079,0.00143563,0.30894 kka2_1:1_G234F,kka2_1:1_234,Kka2,kka2_1:1,P00552,0.308948,NO,234,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-2.9,-4.504,1.604,,0.494,H,A,0.29,-0.29,1.753,,71.59,OOA,-1.86767,0.520039,0.00984449,0.308948 beta-lactamase_2500_K32D,beta-lactamase_2500_32,TEM-1,beta-lactamase_2500,P62593,0.308978,NO,32,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.984,-2.882,0.898,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.361275,0.00401283,0.308978 kka2_1:1_H162D,kka2_1:1_162,Kka2,kka2_1:1,P00552,0.309027,NO,162,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-2.319,-3.685,1.366,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.520039,0.00616145,0.309027 kka2_1:1_A222R,kka2_1:1_222,Kka2,kka2_1:1,P00552,0.309043,NO,222,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.725,-3.736,3.011,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.520039,0.00207657,0.309043 kka2_1:1_V198E,kka2_1:1_198,Kka2,kka2_1:1,P00552,0.309069,NO,198,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.719,-2.905,1.186,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.520039,0.00835002,0.309069 beta-lactamase_39_T179F,beta-lactamase_39_179,TEM-1,beta-lactamase_39,P62593,0.309092,NO,179,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.085,-4.108,3.023,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.0495842,0.00226045,0.309092 beta-lactamase_156_D155G,beta-lactamase_156_155,TEM-1,beta-lactamase_156,P62593,0.309099,NO,155,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.889,-3.177,2.288,,0.049,,B,0.75,-0.9,0.315,,64.69,OAB,-1.62267,0.111618,0.00135315,0.309099 beta-lactamase_625_A246I,beta-lactamase_625_246,TEM-1,beta-lactamase_625,P62593,0.309106,NO,246,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.121,-2.179,0.058,,0.01,E,B,0.46,-1.01,1.201,,73.78,HHH,-1.55633,0.213352,0.00569458,0.309106 kka2_1:8_C192K,kka2_1:8_192,Kka2,kka2_1:8,P00552,0.309119,NO,192,C,K,CK,Special,PositiveCharge,5.07,9.74,4.67,202,121,146,25,108.5,168.6,60.1,-1.067,-3.841,2.774,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.100394,0.00485428,0.309119 kka2_1:8_C192K,kka2_1:8_192,Kka2,kka2_1:8,P00552,0.309119,NO,192,C,K,CK,Special,PositiveCharge,5.07,9.74,4.67,202,121,146,25,108.5,168.6,60.1,-1.067,-3.841,2.774,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.100394,0.00485428,0.309119 beta-lactamase_2500_R220N,beta-lactamase_2500_220,TEM-1,beta-lactamase_2500,P62593,0.309156,NO,220,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-0.942,-3.516,2.574,,0.295,I,A,1.2,-0.76,2.175,,74.48,HBP,-1.33633,0.361275,0.00232421,0.309156 beta-lactamase_625_G76H,beta-lactamase_625_76,TEM-1,beta-lactamase_625,P62593,0.309237,NO,76,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.189,-4.754,3.565,,,H,A,0.29,-0.67,3.059,,67.83,OOH,-1.22267,0.213352,0.00476637,0.309237 kka2_1:1_A14I,kka2_1:1_14,Kka2,kka2_1:1,P00552,0.3093,NO,14,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.837,-3.179,1.342,,0.728,G,A,0.46,0.7,1.17,,71.59,HHH,-1.82567,0.520039,0.00706614,0.3093 beta-lactamase_625_V106P,beta-lactamase_625_106,TEM-1,beta-lactamase_625,P62593,0.309313,NO,106,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.218,-4.094,2.876,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.213352,0.00304168,0.309313 kka2_1:1_E262P,kka2_1:1_262,Kka2,kka2_1:1,P00552,0.309345,NO,262,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-0.829,-3.706,2.877,,0.059,G,A,1.04,-0.18,0.837,,42.42,AAH,-0.816,0.520039,0.0191586,0.309345 kka2_1:4_Q219F,kka2_1:4_219,Kka2,kka2_1:4,P00552,0.309374,NO,219,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-0.93,-4.344,3.414,,0.088,H,A,0.64,-0.85,1.537,,50,HPA,-1.05167,0.168804,0.00237913,0.309374 kka2_1:1_Y257A,kka2_1:1_257,Kka2,kka2_1:1,P00552,0.309385,NO,257,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-1.064,-3.39,2.326,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.520039,0.0148191,0.309385 kka2_1:1_R121H,kka2_1:1_121,Kka2,kka2_1:1,P00552,0.309419,NO,121,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.552,-2.742,1.19,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.520039,0.00523326,0.309419 kka2_1:4_L47G,kka2_1:4_47,Kka2,kka2_1:4,P00552,0.309424,NO,47,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.265,-3.713,2.448,,0.139,E,B,0.55,-0.86,2.369,,63.26,HHH,-1.77933,0.168804,0.00509386,0.309424 beta-lactamase_2500_T187W,beta-lactamase_2500_187,TEM-1,beta-lactamase_2500,P62593,0.309434,NO,187,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.401,-5.371,3.97,,0.007,H,A,0.22,-1.19,3.91,,67.48,PPH,-1.69633,0.361275,0.00491782,0.309434 kka2_1:8_L260T,kka2_1:8_260,Kka2,kka2_1:8,P00552,0.309467,NO,260,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.741,-3.45,2.709,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.100394,0.0233782,0.309467 kka2_1:8_L260T,kka2_1:8_260,Kka2,kka2_1:8,P00552,0.309467,NO,260,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.741,-3.45,2.709,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.100394,0.0233782,0.309467 kka2_1:1_D250W,kka2_1:1_250,Kka2,kka2_1:1,P00552,0.309508,NO,250,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.015,-5.585,4.57,,0.274,.,b,0.75,-0.46,4.177,,51.89,OAP,-1.83933,0.520039,0.0177103,0.309508 kka2_1:1_I228F,kka2_1:1_228,Kka2,kka2_1:1,P00552,0.309548,NO,228,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.142,-3.751,2.609,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.520039,0.00458834,0.309548 beta-lactamase_2500_E119I,beta-lactamase_2500_119,TEM-1,beta-lactamase_2500,P62593,0.309559,NO,119,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.412,-4.096,2.684,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.361275,0.00386966,0.309559 beta-lactamase_2500_I93G,beta-lactamase_2500_93,TEM-1,beta-lactamase_2500,P62593,0.309588,NO,93,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.401,-3.805,2.404,,0.128,E,B,0.48,0.44,19.374,19.374,67.83,BHB,-1.873,0.361275,0.00527066,0.309588 beta-lactamase_R273R,beta-lactamase_273,TEM-1,beta-lactamase,P62593,0.309601,NO,273,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.314,-2.314,,,0.564,H,A,1.2,1.57,,,73.78,ABP,-1.841,0.221079,0.0077952,0.309601 kka2_1:1_E111F,kka2_1:1_111,Kka2,kka2_1:1,P00552,0.309617,NO,111,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.28,-4.475,2.195,,0.155,H,A,1.52,-1.14,15.716,15.716,65.53,HAB,-2.27833,0.520039,0.00746789,0.309617 kka2_1:1_A119W,kka2_1:1_119,Kka2,kka2_1:1,P00552,0.309662,NO,119,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.073,-5.403,4.33,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.520039,0.00441074,0.309662 kka2_1:4_S32F,kka2_1:4_32,Kka2,kka2_1:4,P00552,0.309688,NO,32,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-0.804,-4.095,3.291,,0.768,S,b,0.27,3.75,,,,OPA,-1.74533,0.168804,0.00149998,0.309688 kka2_1:4_C209Q,kka2_1:4_209,Kka2,kka2_1:4,P00552,0.309775,NO,209,C,Q,CQ,Special,Polar,5.07,6.24429,1.17429,154,121,146,25,108.5,143.8,35.3,-0.906,-4.376,3.47,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.168804,0.00260862,0.309775 kka2_1:1_L152T,kka2_1:1_152,Kka2,kka2_1:1,P00552,0.309979,NO,152,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.521,-2.936,1.415,,0.547,.,A,0.55,1.36,1.589,,63.64,OHH,-1.162,0.520039,0.00674868,0.309979 kka2_1:1_L174T,kka2_1:1_174,Kka2,kka2_1:1,P00552,0.309996,NO,174,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.952,-3.474,2.522,,,H,A,0.55,-0.31,13.276,13.276,51.89,BHB,-2.08533,0.520039,0.00438501,0.309996 kka2_1:1_A224N,kka2_1:1_224,Kka2,kka2_1:1,P00552,0.310039,NO,224,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.977,-3.898,2.921,,,H,A,0.46,-1.26,1.725,,63.64,HHP,-1.41033,0.520039,0.00352047,0.310039 kka2_1:1_A144W,kka2_1:1_144,Kka2,kka2_1:1,P00552,0.310047,NO,144,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.859,-5.395,4.536,,,H,A,0.46,0.21,0.842,,52.65,BHB,-1.72933,0.520039,0.00231095,0.310047 kka2_1:1_Q42M,kka2_1:1_42,Kka2,kka2_1:1,P00552,0.310101,NO,42,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.907,-4.883,1.976,,1.044,T,B,0.4,-0.8,2.792,,71.59,HPO,-2.12433,0.520039,0.00679212,0.310101 kka2_1:1_G245F,kka2_1:1_245,Kka2,kka2_1:1,P00552,0.310144,NO,245,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.812,-4.364,3.552,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.520039,0.00683899,0.310144 beta-lactamase_625_C75E,beta-lactamase_625_75,TEM-1,beta-lactamase_625,P62593,0.310146,NO,75,C,E,CE,Special,negativeCharge,5.07,3.22,-1.85,170,121,147,26,108.5,138.4,29.9,-1.245,-3.874,2.629,,,H,A,0.46,-0.87,2.141,,50,HOO,-1.24333,0.213352,0.0034616,0.310146 kka2_1:1_V97Y,kka2_1:1_97,Kka2,kka2_1:1,P00552,0.310155,NO,97,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.453,-4.124,2.671,,0.083,,B,1.48,-0.83,13.576,13.576,53.03,AHO,-1.85067,0.520039,0.00737869,0.310155 kka2_1:2_R147T,kka2_1:2_147,Kka2,kka2_1:2,P00552,0.310209,NO,147,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.123,-3.56,2.437,,0.094,H,A,1.2,0.97,0.425,,64.02,PBH,-1.98267,0.295029,0.00549168,0.310209 beta-lactamase_625_W288E,beta-lactamase_625_288,TEM-1,beta-lactamase_625,P62593,0.310222,NO,288,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,,,,,,,,,,,,,BHO,,0.213352,,0.310222 kka2_1:8_L174D,kka2_1:8_174,Kka2,kka2_1:8,P00552,0.310274,NO,174,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.952,-4.154,3.202,,,H,A,1.59,-0.31,1.204,,51.89,BHB,-2.08533,0.100394,0.00438501,0.310274 kka2_1:8_L174D,kka2_1:8_174,Kka2,kka2_1:8,P00552,0.310274,NO,174,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.952,-4.154,3.202,,,H,A,1.59,-0.31,1.204,,51.89,BHB,-2.08533,0.100394,0.00438501,0.310274 beta-lactamase_156_L120D,beta-lactamase_156_120,TEM-1,beta-lactamase_156,P62593,0.310298,NO,120,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.044,-4.076,3.032,,,H,A,0.55,-1.13,7.813,,64.69,AHO,-1.13633,0.111618,0.00143563,0.310298 kka2_1:1_Q61C,kka2_1:1_61,Kka2,kka2_1:1,P00552,0.310315,NO,61,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.982,-5.1,2.118,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.520039,0.00612092,0.310315 kka2_1:1_P132K,kka2_1:1_132,Kka2,kka2_1:1,P00552,0.310324,NO,132,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.775,-3.483,2.708,,0.692,.,A,0.52,0.56,0.224,,44.7,OOH,-0.825667,0.520039,0.0018489,0.310324 PSD95pdz3_G330L,PSD95pdz3_330,PSD95pdz3,PSD95pdz3,P31016,0.310336,NO,330,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.008,-3.49,2.482,4.68351,,,,,31.405,,,,OOA,-1.14,0.0758425,0.000962386,0.310336 kka2_1:1_L92T,kka2_1:1_92,Kka2,kka2_1:1,P00552,0.310347,NO,92,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.893,-3.472,2.579,,0.007,E,B,0.55,-0.19,1.447,,63.26,HHH,-0.962,0.520039,0.00307177,0.310347 beta-lactamase_625_A34P,beta-lactamase_625_34,TEM-1,beta-lactamase_625,P62593,0.310386,NO,34,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.059,-4.024,1.965,,,H,A,0.46,-0.54,3.614,,73.78,AHA,-1.74967,0.213352,0.00407913,0.310386 beta-lactamase_2500_T179F,beta-lactamase_2500_179,TEM-1,beta-lactamase_2500,P62593,0.310402,NO,179,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.085,-4.108,3.023,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.361275,0.00226045,0.310402 kka2_1:2_I29Y,kka2_1:2_29,Kka2,kka2_1:2,P00552,0.310419,NO,29,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.692,-4.24,2.548,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.295029,0.00619521,0.310419 kka2_1:1_I246N,kka2_1:1_246,Kka2,kka2_1:1,P00552,0.310523,NO,246,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-2.008,-4.146,2.138,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.520039,0.0139479,0.310523 beta-lactamase_156_I45K,beta-lactamase_156_45,TEM-1,beta-lactamase_156,P62593,0.310619,NO,45,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-2.421,-3.76,1.339,,,E,B,0.48,-0.3,2.256,,77.62,HHA,-2.30267,0.111618,0.00452842,0.310619 beta-lactamase_625_L284N,beta-lactamase_625_284,TEM-1,beta-lactamase_625,P62593,0.310627,NO,284,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.213352,0.0686156,0.310627 hsp90_A587Y,hsp90_587,hsp90,hsp90,P02829,0.310665,NO,587,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.456,-3.316,0,4.91216,0.049,H,A,0.55,-0.02,,,,PHP,-2.757,0.368192,0.000222939,0.310665 beta-lactamase_39_L74F,beta-lactamase_39_74,TEM-1,beta-lactamase_39,P62593,0.310716,NO,74,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.296,-3.848,2.552,,,H,A,0.55,-0.91,1.581,,50,HHO,-1.34933,0.0495842,0.00493255,0.310716 kka2_1:1_D156V,kka2_1:1_156,Kka2,kka2_1:1,P00552,0.31072,NO,156,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.696,-3.632,1.936,,0.884,T,A,0.75,1.87,1.044,,65.53,PAA,-1.765,0.520039,0.00926998,0.31072 kka2_1:1_F240P,kka2_1:1_240,Kka2,kka2_1:1,P00552,0.310729,NO,240,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-0.911,-4.356,3.445,,,H,A,1.62,-1.21,5.798,,50.38,BHH,-1.67267,0.520039,0.00552543,0.310729 beta-lactamase_625_M115K,beta-lactamase_625_115,TEM-1,beta-lactamase_625,P62593,0.310741,NO,115,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.389,-3.553,2.164,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.213352,0.0034337,0.310741 kka2_1:1_K50L,kka2_1:1_50,Kka2,kka2_1:1,P00552,0.310826,NO,50,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-0.833,-3.41,2.577,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.520039,0.00138626,0.310826 beta-lactamase_2500_I93E,beta-lactamase_2500_93,TEM-1,beta-lactamase_2500,P62593,0.310865,NO,93,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.401,-3.886,2.485,,0.128,E,B,0.48,0.44,19.374,19.374,67.83,BHB,-1.873,0.361275,0.00527066,0.310865 kka2_1:1_Q252Y,kka2_1:1_252,Kka2,kka2_1:1,P00552,0.310951,NO,252,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.63,-4.393,1.763,,0.906,H,A,0.64,0.35,1.369,,92.05,PPB,-2.20733,0.520039,0.0121001,0.310951 beta-lactamase_625_L191E,beta-lactamase_625_191,TEM-1,beta-lactamase_625,P62593,0.31099,NO,191,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.087,-3.859,2.772,,,H,A,0.55,0.09,1.908,,63.29,BHH,-1.445,0.213352,0.00263549,0.31099 beta-lactamase_L136G,beta-lactamase_136,TEM-1,beta-lactamase,P62593,0.311009,NO,136,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.232,-3.856,2.624,5.31114,,H,A,2.89,-0.34,1.539,,48.95,HHH,-1.088,0.221079,0.00442304,0.311009 kka2_1:4_I196E,kka2_1:4_196,Kka2,kka2_1:4,P00552,0.311066,NO,196,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-2.115,-4.03,1.915,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.168804,0.0107273,0.311066 kka2_1:8_R226P,kka2_1:8_226,Kka2,kka2_1:8,P00552,0.311079,NO,226,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.392,-4.085,2.693,,0.222,H,A,0.16,-0.71,3.818,,56.06,PBA,-1.84767,0.100394,0.0108032,0.311079 kka2_1:8_R226P,kka2_1:8_226,Kka2,kka2_1:8,P00552,0.311079,NO,226,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.392,-4.085,2.693,,0.222,H,A,0.16,-0.71,3.818,,56.06,PBA,-1.84767,0.100394,0.0108032,0.311079 beta-lactamase_625_W227A,beta-lactamase_625_227,TEM-1,beta-lactamase_625,P62593,0.311127,NO,227,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-0.982,-3.46,2.478,,0.272,,B,0.47,-0.29,2.533,,74.48,OHH,-1.595,0.213352,0.00226019,0.311127 beta-lactamase_D177S,beta-lactamase_177,TEM-1,beta-lactamase,P62593,0.311147,NO,177,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.967,-3.186,2.219,5.08038,0.006,T,L,1.59,-1.02,3.536,,64.69,BAP,-0.873667,0.221079,0.000864022,0.311147 kka2_1:1_D250F,kka2_1:1_250,Kka2,kka2_1:1,P00552,0.311232,NO,250,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.015,-4.403,3.388,,0.274,.,b,0.75,-0.46,4.177,,51.89,OAP,-1.83933,0.520039,0.0177103,0.311232 beta-lactamase_625_F64N,beta-lactamase_625_64,TEM-1,beta-lactamase_625,P62593,0.311259,NO,64,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-0.841,-4.123,3.282,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.213352,0.000947691,0.311259 beta-lactamase_625_W288R,beta-lactamase_625_288,TEM-1,beta-lactamase_625,P62593,0.311267,NO,288,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,,,,,,,,,,,,,BHO,,0.213352,,0.311267 beta-lactamase_2500_S266P,beta-lactamase_2500_266,TEM-1,beta-lactamase_2500,P62593,0.311371,NO,266,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.361275,0.0140785,0.311371 kka2_1:2_I228E,kka2_1:2_228,Kka2,kka2_1:2,P00552,0.311414,NO,228,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.142,-3.95,2.808,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.295029,0.00458834,0.311414 kka2_1:2_L174N,kka2_1:2_174,Kka2,kka2_1:2,P00552,0.311432,NO,174,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.952,-4.185,3.233,,,H,A,1.59,-0.31,8.521,,51.89,BHB,-2.08533,0.295029,0.00438501,0.311432 beta-lactamase_625_R59D,beta-lactamase_625_59,TEM-1,beta-lactamase_625,P62593,0.311462,NO,59,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.345,-3.634,2.289,,0.329,S,L,1.2,-0.09,2.995,,73.08,HBO,-2.24267,0.213352,0.00318082,0.311462 kka2_1:1_P167V,kka2_1:1_167,Kka2,kka2_1:1,P00552,0.311462,NO,167,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-2.403,-2.424,0.021,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.520039,0.00543203,0.311462 beta-lactamase_625_L223Y,beta-lactamase_625_223,TEM-1,beta-lactamase_625,P62593,0.31147,NO,223,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.055,-3.889,2.834,,0.27,,B,0.55,0.09,1.633,,74.48,HHO,-1.35033,0.213352,0.00372793,0.31147 beta-lactamase_2500_S104F,beta-lactamase_2500_104,TEM-1,beta-lactamase_2500,P62593,0.311573,NO,104,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.015,-4.127,3.112,,0.04,,b,0.27,0.57,1.133,,63.29,HPO,-1.05267,0.361275,0.00218083,0.311573 hsp90_S586E,hsp90_586,hsp90,hsp90,P02829,0.311582,NO,586,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.764,-2.818,0,4.65438,,,B,0.93,0.15,,,,HPH,-3.157,0.368192,0.000222939,0.311582 kka2_1:2_H124Y,kka2_1:2_124,Kka2,kka2_1:2,P00552,0.311587,NO,124,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-0.84,-3.291,2.451,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.295029,0.00211296,0.311587 kka2_1:2_G233T,kka2_1:2_233,Kka2,kka2_1:2,P00552,0.311588,NO,233,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.748,-3.674,2.926,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.295029,0.00232366,0.311588 beta-lactamase_625_D174R,beta-lactamase_625_174,TEM-1,beta-lactamase_625,P62593,0.311689,NO,174,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.738,-3.933,3.195,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.213352,0.00125633,0.311689 kka2_1:4_P109F,kka2_1:4_109,Kka2,kka2_1:4,P00552,0.311694,NO,109,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.412,-4.386,2.974,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.168804,0.0070929,0.311694 kka2_1:1_L184K,kka2_1:1_184,Kka2,kka2_1:1,P00552,0.311723,NO,184,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.496,-2.828,1.332,,0.489,E,B,0.55,-0.06,19.127,19.127,63.26,AHH,-1.24833,0.520039,0.00518742,0.311723 beta-lactamase_2500_T263G,beta-lactamase_2500_263,TEM-1,beta-lactamase_2500,P62593,0.31175,NO,263,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.031,-3.618,1.587,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.361275,0.0110582,0.31175 kka2_1:1_W24Q,kka2_1:1_24,Kka2,kka2_1:1,P00552,0.311799,NO,24,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-1.779,-4.365,2.586,,0.477,E,B,0.47,-0.21,2.375,,56.06,AHH,-2.24467,0.520039,0.00631564,0.311799 kka2_1:1_P98V,kka2_1:1_98,Kka2,kka2_1:1,P00552,0.311807,NO,98,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.526,-3.691,2.165,,0.391,S,B,0.52,-0.65,1.521,,63.26,HOO,-1.19167,0.520039,0.00622754,0.311807 beta-lactamase_2500_G154Y,beta-lactamase_2500_154,TEM-1,beta-lactamase_2500,P62593,0.311893,NO,154,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.823,-4.424,3.601,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.361275,0.00180205,0.311893 beta-lactamase_2500_D174N,beta-lactamase_2500_174,TEM-1,beta-lactamase_2500,P62593,0.311946,NO,174,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.738,-3.223,2.485,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.361275,0.00125633,0.311946 kka2_1:1_W15P,kka2_1:1_15,Kka2,kka2_1:1,P00552,0.311964,NO,15,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-1.392,-4.349,2.957,,0.01,G,A,0.47,0.15,20.149,20.149,52.27,HHH,-2.10533,0.520039,0.00585505,0.311964 beta-lactamase_156_I45D,beta-lactamase_156_45,TEM-1,beta-lactamase_156,P62593,0.311998,NO,45,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-2.421,-3.902,1.481,,,E,B,0.48,-0.3,2.256,,77.62,HHA,-2.30267,0.111618,0.00452842,0.311998 kka2_1:4_L19H,kka2_1:4_19,Kka2,kka2_1:4,P00552,0.311999,NO,19,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.254,-3.254,2,,0.08,T,A,1.59,-0.26,2.645,,65.53,BHH,-2.221,0.168804,0.00620703,0.311999 beta-lactamase_2500_Q204P,beta-lactamase_2500_204,TEM-1,beta-lactamase_2500,P62593,0.312019,NO,204,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-1.382,-3.857,2.475,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.361275,0.00364106,0.312019 kka2_1:4_G205F,kka2_1:4_205,Kka2,kka2_1:4,P00552,0.312024,NO,205,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.596,-4.32,3.724,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.168804,0.00221855,0.312024 beta-lactamase_625_T179F,beta-lactamase_625_179,TEM-1,beta-lactamase_625,P62593,0.312041,NO,179,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.085,-4.108,3.023,,,E,B,0.22,-1.38,0.367,,73.08,PPH,-1.557,0.213352,0.00226045,0.312041 beta-lactamase_156_V42Q,beta-lactamase_156_42,TEM-1,beta-lactamase_156,P62593,0.312068,NO,42,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.564,-4.229,2.665,,0.017,E,B,0.44,-0.51,2.576,,63.99,BHO,-1.042,0.111618,0.00404515,0.312068 beta-lactamase_39_K232G,beta-lactamase_39_232,TEM-1,beta-lactamase_39,P62593,0.312094,NO,232,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.012,-3.401,2.389,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.0495842,0.00313441,0.312094 kka2_1:2_W15D,kka2_1:2_15,Kka2,kka2_1:2,P00552,0.312108,NO,15,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-1.392,-4.212,2.82,,0.01,G,A,0.47,0.15,2.586,,52.27,HHH,-2.10533,0.295029,0.00585505,0.312108 Pab1_K131L,Pab1_131,Pab1,Pab1,P04147,0.312146,NO,131,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.083,-3.175,2.092,,0.462,E,B,1.82,0.57,,,,HBP,-1.12467,0.175299,0.000349395,0.312146 beta-lactamase_156_N168Y,beta-lactamase_156_168,TEM-1,beta-lactamase_156,P62593,0.312173,NO,168,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-1.029,-4.205,3.176,,0.113,G,A,0.61,-0.4,1.014,,44.41,HPA,-1.13233,0.111618,0.00288667,0.312173 beta-lactamase_2500_P65Q,beta-lactamase_2500_65,TEM-1,beta-lactamase_2500,P62593,0.312261,NO,65,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.894,-3.954,3.06,,0.098,E,B,0.52,-0.62,0.3,,40.56,HOH,-1.03233,0.361275,0.00152776,0.312261 kka2_1:4_V185S,kka2_1:4_185,Kka2,kka2_1:4,P00552,0.312291,NO,185,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.045,-3.595,2.55,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.168804,0.00367031,0.312291 beta-lactamase_156_M67W,beta-lactamase_156_67,TEM-1,beta-lactamase_156,P62593,0.312298,NO,67,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-2.231,-5.379,3.148,,0.006,G,P,0.55,-0.81,1.463,,65.03,HHP,-1.502,0.111618,0.00409753,0.312298 kka2_1:4_L212S,kka2_1:4_212,Kka2,kka2_1:4,P00552,0.312344,NO,212,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.904,-3.574,2.67,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.168804,0.0031426,0.312344 beta-lactamase_2500_G52V,beta-lactamase_2500_52,TEM-1,beta-lactamase_2500,P62593,0.312396,NO,52,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.149,-3.738,2.589,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.361275,0.00340138,0.312396 kka2_1:1_I221D,kka2_1:1_221,Kka2,kka2_1:1,P00552,0.312423,NO,221,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.739,-4.188,2.449,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.520039,0.00945908,0.312423 beta-lactamase_D48P,beta-lactamase_48,TEM-1,beta-lactamase,P62593,0.312442,NO,48,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.101,-3.766,2.665,4.89966,0.189,E,B,0.23,0.21,1.281,,50.35,HAH,-1.62467,0.221079,0.0027273,0.312442 kka2_1:1_E142F,kka2_1:1_142,Kka2,kka2_1:1,P00552,0.312452,NO,142,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.221,-4.452,2.231,,0.471,H,A,1.52,0.85,3.626,,65.53,HAB,-2.08033,0.520039,0.00748883,0.312452 kka2_1:1_G181I,kka2_1:1_181,Kka2,kka2_1:1,P00552,0.312454,NO,181,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-2.698,-3.104,0.406,,0.379,S,B,0.75,0.78,15.356,15.356,71.59,AOA,-2.21,0.520039,0.00728319,0.312454 beta-lactamase_39_G43Q,beta-lactamase_39_43,TEM-1,beta-lactamase_39,P62593,0.312494,NO,43,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.62,-4.124,3.504,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.0495842,0.00120151,0.312494 kka2_1:1_D118N,kka2_1:1_118,Kka2,kka2_1:1,P00552,0.312538,NO,118,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.07,-3.163,1.093,,0.61,H,A,0.75,-0.05,13.434,13.434,64.39,HAH,-1.32367,0.520039,0.0067852,0.312538 kka2_1:8_M197H,kka2_1:8_197,Kka2,kka2_1:8,P00552,0.312549,NO,197,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.707,-4.99,3.283,,0.121,E,B,1.59,-1.19,4.408,,65.53,HHH,-1.847,0.100394,0.00921295,0.312549 kka2_1:8_M197H,kka2_1:8_197,Kka2,kka2_1:8,P00552,0.312549,NO,197,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.707,-4.99,3.283,,0.121,E,B,1.59,-1.19,4.408,,65.53,HHH,-1.847,0.100394,0.00921295,0.312549 beta-lactamase_L79G,beta-lactamase_79,TEM-1,beta-lactamase,P62593,0.312558,NO,79,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.842,-3.806,2.964,4.98681,0.007,H,A,1.07,-0.16,0.823,,50.35,HHP,-1.44333,0.221079,0.000947397,0.312558 PSD95pdz3_A375W,PSD95pdz3_375,PSD95pdz3,PSD95pdz3,P31016,0.31258,NO,375,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.307,-5.004,3.697,5.05512,,,,,13.888,,,,PHH,-1.43767,0.0758425,0.000356809,0.31258 beta-lactamase_2500_T158G,beta-lactamase_2500_158,TEM-1,beta-lactamase_2500,P62593,0.312612,NO,158,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.116,-3.288,2.172,,0.036,,B,0.22,-0.85,1.344,,69.58,HPB,-1.269,0.361275,0.00341825,0.312612 beta-lactamase_156_S233N,beta-lactamase_156_233,TEM-1,beta-lactamase_156,P62593,0.312623,NO,233,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.886,-2.73,0.844,,0.016,E,B,0.27,-1.01,4.111,,77.62,BPO,-1.17267,0.111618,0.00311415,0.312623 beta-lactamase_156_F70K,beta-lactamase_156_70,TEM-1,beta-lactamase_156,P62593,0.312641,NO,70,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.169,-3.812,2.643,,,H,A,0.58,-1.34,1.918,,63.99,PHB,-0.980667,0.111618,0.00193499,0.312641 kka2_1:4_S204W,kka2_1:4_204,Kka2,kka2_1:4,P00552,0.312644,NO,204,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.353,-5.392,4.039,,0.144,E,A,0.27,-1.2,2.442,,65.53,HPO,-0.953333,0.168804,0.00881794,0.312644 beta-lactamase_2500_G226I,beta-lactamase_2500_226,TEM-1,beta-lactamase_2500,P62593,0.312659,NO,226,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.461,-4.177,2.716,,0.701,T,l,0.29,-0.25,5.086,,74.48,HOH,-1.42933,0.361275,0.00665294,0.312659 beta-lactamase_625_D177E,beta-lactamase_625_177,TEM-1,beta-lactamase_625,P62593,0.312661,NO,177,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.967,-2.98,2.013,,0.006,T,L,0.75,-1.02,1.333,,64.69,BAP,-0.873667,0.213352,0.000864022,0.312661 kka2_1:4_M148Y,kka2_1:4_148,Kka2,kka2_1:4,P00552,0.312664,NO,148,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.847,-4.225,2.378,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.168804,0.00982664,0.312664 kka2_1:4_L126H,kka2_1:4_126,Kka2,kka2_1:4,P00552,0.312713,NO,126,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.246,-4.997,3.751,,0.285,S,B,0.55,0.12,0.302,,51.89,PHA,-1.744,0.168804,0.0066485,0.312713 kka2_1:4_D208M,kka2_1:4_208,Kka2,kka2_1:4,P00552,0.312766,NO,208,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.708,-4.958,4.25,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.168804,0.00212588,0.312766 beta-lactamase_2500_L73W,beta-lactamase_2500_73,TEM-1,beta-lactamase_2500,P62593,0.312769,NO,73,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.507,-5.171,3.664,,,H,A,0.55,-0.64,2.178,,67.83,HHH,-1.487,0.361275,0.00488983,0.312769 kka2_1:1_D227T,kka2_1:1_227,Kka2,kka2_1:1,P00552,0.312769,NO,227,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.758,-3.153,1.395,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.520039,0.00745029,0.312769 kka2_1:1_V36P,kka2_1:1_36,Kka2,kka2_1:1,P00552,0.312771,NO,36,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-0.898,-3.99,3.092,,0.292,E,B,0.44,0.21,0.278,,52.27,HHH,-1.484,0.520039,0.00245633,0.312771 kka2_1:4_A119W,kka2_1:4_119,Kka2,kka2_1:4,P00552,0.312786,NO,119,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.073,-5.403,4.33,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.168804,0.00441074,0.312786 beta-lactamase_625_I277A,beta-lactamase_625_277,TEM-1,beta-lactamase_625,P62593,0.312797,NO,277,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.213352,0.0169305,0.312797 kka2_1:8_F206H,kka2_1:8_206,Kka2,kka2_1:8,P00552,0.312815,NO,206,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.349,-4.415,3.066,,0.006,E,B,1.62,-1.21,1.052,,63.64,OHH,-1.04,0.100394,0.00936868,0.312815 kka2_1:8_F206H,kka2_1:8_206,Kka2,kka2_1:8,P00552,0.312815,NO,206,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.349,-4.415,3.066,,0.006,E,B,1.62,-1.21,1.052,,63.64,OHH,-1.04,0.100394,0.00936868,0.312815 beta-lactamase_2500_E164N,beta-lactamase_2500_164,TEM-1,beta-lactamase_2500,P62593,0.312872,NO,164,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-0.948,-3.497,2.549,,0.011,T,B,1.04,-0.4,0.352,,64.69,HAO,-1.388,0.361275,0.00137286,0.312872 Pab1_I128F,Pab1_128,Pab1,Pab1,P04147,0.312878,NO,128,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.345,-3.578,2.233,,0.008,E,B,1.68,-0.6,1.706,,78.68,PHH,-1.231,0.175299,0.00104192,0.312878 Pab1_H172I,Pab1_172,Pab1,Pab1,P04147,0.312884,NO,172,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-1.21,-3.827,2.617,,0.076,E,B,0.35,-0.87,,,,HBH,-1.26667,0.175299,0.000296642,0.312884 beta-lactamase_2500_G234E,beta-lactamase_2500_234,TEM-1,beta-lactamase_2500,P62593,0.312925,NO,234,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.62,-3.665,3.045,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.361275,0.000889577,0.312925 kka2_1:2_L259A,kka2_1:2_259,Kka2,kka2_1:2,P00552,0.312943,NO,259,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.088,-2.512,1.424,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.295029,0.0206964,0.312943 beta-lactamase_2500_L284N,beta-lactamase_2500_284,TEM-1,beta-lactamase_2500,P62593,0.312977,NO,284,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.361275,0.0686156,0.312977 E1_Ubiquitin_G76C,E1_Ubiquitin_76,Uba1,E1_Ubiquitin,P0CG63,0.312997,NO,76,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.999,-4.898,3.899,,0.23,,B,0.75,0.08,1.702,,83.73,OOO,-0.999,0.18783,0.00125575,0.312997 beta-lactamase_2500_E35G,beta-lactamase_2500_35,TEM-1,beta-lactamase_2500,P62593,0.313003,NO,35,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-0.869,-3.356,2.487,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.361275,0.00174441,0.313003 beta-lactamase_2500_S283P,beta-lactamase_2500_283,TEM-1,beta-lactamase_2500,P62593,0.313064,NO,283,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.361275,0.0429138,0.313064 gb1_A252N,gb1_252,gb1,gb1,P06654,0.313119,NO,252,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.175,-3.633,2.458,,,,,,,,,,PHA,-1.55967,0.177985,0.00125598,0.313119 gb1_D262P,gb1_262,gb1,gb1,P06654,0.313119,NO,262,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-3.132,-3.564,0.432,,,,,,,1.304,,45.54,PAP,-2.05233,0.177985,0.00413102,0.313119 gb1_G267V,gb1_267,gb1,gb1,P06654,0.313119,NO,267,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.676,-3.132,1.456,,,,,,,1.361,,12.72,AOA,-1.61833,0.177985,0.00264655,0.313119 gb1_L231K,gb1_231,gb1,gb1,P06654,0.313119,NO,231,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.603,-3.493,1.89,,,,,,,0.219,,11.83,BHH,-1.82633,0.177985,0.00322797,0.313119 gb1_N261R,gb1_261,gb1,gb1,P06654,0.313119,NO,261,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-1.863,-3.516,1.653,,,,,,,1.191,,44.87,HPA,-2.16033,0.177985,0.0061875,0.313119 kka2_1:4_R140N,kka2_1:4_140,Kka2,kka2_1:4,P00552,0.313195,NO,140,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.351,-3.614,2.263,,0.12,H,A,1.2,0.2,2.561,,53.03,BBH,-1.885,0.168804,0.00430167,0.313195 kka2_1:4_R211E,kka2_1:4_211,Kka2,kka2_1:4,P00552,0.313195,NO,211,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-0.899,-3.317,2.418,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.168804,0.00204888,0.313195 kka2_1:4_R211Y,kka2_1:4_211,Kka2,kka2_1:4,P00552,0.313195,NO,211,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-0.899,-4.076,3.177,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.168804,0.00204888,0.313195 kka2_1:8_I207N,kka2_1:8_207,Kka2,kka2_1:8,P00552,0.313215,NO,207,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.175,-4.238,3.063,,0.293,,B,1.52,-1.12,1.306,,56.06,HHA,-1.07733,0.100394,0.00611824,0.313215 kka2_1:8_I207N,kka2_1:8_207,Kka2,kka2_1:8,P00552,0.313215,NO,207,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.175,-4.238,3.063,,0.293,,B,1.52,-1.12,1.306,,56.06,HHA,-1.07733,0.100394,0.00611824,0.313215 kka2_1:1_L60G,kka2_1:1_60,Kka2,kka2_1:1,P00552,0.313302,NO,60,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.997,-3.865,2.868,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.520039,0.00262176,0.313302 beta-lactamase_2500_T179N,beta-lactamase_2500_179,TEM-1,beta-lactamase_2500,P62593,0.313343,NO,179,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.085,-3.487,2.402,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.361275,0.00226045,0.313343 kka2_1:2_D220C,kka2_1:2_220,Kka2,kka2_1:2,P00552,0.313371,NO,220,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.787,-5.083,4.296,,,H,A,0.75,-1.14,0.745,,46.59,PAH,-1.152,0.295029,0.00158066,0.313371 kka2_1:2_A150I,kka2_1:2_150,Kka2,kka2_1:2,P00552,0.313372,NO,150,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.949,-3.788,2.839,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.295029,0.0045009,0.313372 beta-lactamase_625_A215W,beta-lactamase_625_215,TEM-1,beta-lactamase_625,P62593,0.313392,NO,215,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.503,-5.336,3.833,,,,a,0.46,-0.93,3.583,,74.48,HHO,-1.42633,0.213352,0.00544007,0.313392 kka2_1:4_A215K,kka2_1:4_215,Kka2,kka2_1:4,P00552,0.313392,NO,215,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.968,-3.512,2.544,,0.039,E,B,0.46,-0.59,0.754,,50.38,HHA,-1.00467,0.168804,0.00529129,0.313392 kka2_1:2_A117H,kka2_1:2_117,Kka2,kka2_1:2,P00552,0.313443,NO,117,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.828,-4.772,3.944,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.295029,0.00282984,0.313443 kka2_1:2_L241V,kka2_1:2_241,Kka2,kka2_1:2,P00552,0.313467,NO,241,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.158,-3.12,1.962,,0.08,H,A,0.55,-0.82,1.598,,63.26,HHH,-1.58533,0.295029,0.0117299,0.313467 kka2_1:4_I29Y,kka2_1:4_29,Kka2,kka2_1:4,P00552,0.313478,NO,29,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.692,-4.24,2.548,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.168804,0.00619521,0.313478 beta-lactamase_39_I125D,beta-lactamase_39_125,TEM-1,beta-lactamase_39,P62593,0.313626,NO,125,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.441,-3.998,2.557,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.0495842,0.00383964,0.313626 kka2_1:2_A215F,kka2_1:2_215,Kka2,kka2_1:2,P00552,0.313684,NO,215,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.968,-4.18,3.212,,0.039,E,B,0.46,-0.59,2.137,,50.38,HHA,-1.00467,0.295029,0.00529129,0.313684 kka2_1:2_D227T,kka2_1:2_227,Kka2,kka2_1:2,P00552,0.3137,NO,227,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.758,-3.153,1.395,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.295029,0.00745029,0.3137 kka2_1:1_L39A,kka2_1:1_39,Kka2,kka2_1:1,P00552,0.313736,NO,39,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.223,-2.615,1.392,,,E,B,0.55,-1.21,0.925,,71.59,BHP,-1.69167,0.520039,0.00493618,0.313736 kka2_1:8_V49N,kka2_1:8_49,Kka2,kka2_1:8,P00552,0.313747,NO,49,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.614,-4.184,2.57,,,E,B,1.48,-0.77,1.31,,64.39,HHB,-1.3,0.100394,0.00615685,0.313747 kka2_1:8_V49N,kka2_1:8_49,Kka2,kka2_1:8,P00552,0.313747,NO,49,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.614,-4.184,2.57,,,E,B,1.48,-0.77,1.31,,64.39,HHB,-1.3,0.100394,0.00615685,0.313747 beta-lactamase_625_C121P,beta-lactamase_625_121,TEM-1,beta-lactamase_625,P62593,0.313765,NO,121,C,P,CP,Special,Special,5.07,6.3,1.23,169,121,115,-6,108.5,112.7,4.2,-0.953,-4.102,3.149,,,H,A,0.46,-0.81,1.143,,63.29,HOP,-1.46767,0.213352,0.000744322,0.313765 kka2_1:1_I228M,kka2_1:1_228,Kka2,kka2_1:1,P00552,0.313776,NO,228,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.142,-4.08,2.938,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.520039,0.00458834,0.313776 kka2_1:1_L260I,kka2_1:1_260,Kka2,kka2_1:1,P00552,0.313808,NO,260,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.741,-2.914,2.173,,0.022,H,A,0.55,-0.52,,,,HHA,-0.845667,0.520039,0.0233782,0.313808 kka2_1:8_D101K,kka2_1:8_101,Kka2,kka2_1:8,P00552,0.31388,NO,101,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.028,-3.563,2.535,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.100394,0.00423361,0.31388 kka2_1:8_D101K,kka2_1:8_101,Kka2,kka2_1:8,P00552,0.31388,NO,101,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.028,-3.563,2.535,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.100394,0.00423361,0.31388 kka2_1:1_E169T,kka2_1:1_169,Kka2,kka2_1:1,P00552,0.313887,NO,169,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.996,-2.692,0.696,,0.422,H,A,1.04,0.3,7.546,7.546,65.53,HAH,-1.755,0.520039,0.00730086,0.313887 kka2_1:1_Q27Y,kka2_1:1_27,Kka2,kka2_1:1,P00552,0.313893,NO,27,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-1.659,-4.273,2.614,,0.608,.,A,0.64,0.71,0.521,,65.53,PPP,-1.90733,0.520039,0.00595365,0.313893 kka2_1:4_I228G,kka2_1:4_228,Kka2,kka2_1:4,P00552,0.313899,NO,228,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.142,-3.869,2.727,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.168804,0.00458834,0.313899 kka2_1:4_K112S,kka2_1:4_112,Kka2,kka2_1:4,P00552,0.313902,NO,112,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-2.491,-2.816,0.325,,0.076,H,A,2.34,-1.37,0.39,,56.06,ABH,-2.00133,0.168804,0.00645389,0.313902 beta-lactamase_L192E,beta-lactamase_192,TEM-1,beta-lactamase,P62593,0.313912,NO,192,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.254,-3.893,2.639,5.68899,0.095,H,A,1.3,0.35,1.756,,60.14,HHP,-1.41833,0.221079,0.00558728,0.313912 kka2_1:1_H135M,kka2_1:1_135,Kka2,kka2_1:1,P00552,0.313949,NO,135,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-1.331,-4.614,3.283,,0.071,.,a,0.17,0.65,3.574,,53.03,ABP,-1.77367,0.520039,0.00532566,0.313949 beta-lactamase_2500_R63W,beta-lactamase_2500_63,TEM-1,beta-lactamase_2500,P62593,0.313954,NO,63,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-0.943,-5.32,4.377,,0.218,,B,1.2,-0.31,0.929,,44.06,ABH,-0.992333,0.361275,0.00126938,0.313954 kka2_1:1_A25L,kka2_1:1_25,Kka2,kka2_1:1,P00552,0.313969,NO,25,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.496,-3.561,1.065,,0.427,E,B,0.46,-0.47,6.872,6.872,65.53,HHP,-2.15167,0.520039,0.00595636,0.313969 beta-lactamase_625_C121T,beta-lactamase_625_121,TEM-1,beta-lactamase_625,P62593,0.314002,NO,121,C,T,CT,Special,Polar,5.07,5.6,0.53,149,121,119,-2,108.5,116.1,7.6,-0.953,-3.447,2.494,,,H,A,0.46,-0.81,1.143,,63.29,HOP,-1.46767,0.213352,0.000744322,0.314002 beta-lactamase_2500_P224F,beta-lactamase_2500_224,TEM-1,beta-lactamase_2500,P62593,0.314051,NO,224,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.893,-4.486,3.593,,0.383,,B,0.52,-0.3,2.666,,74.48,HOH,-1.26433,0.361275,0.00189564,0.314051 kka2_1:2_L260I,kka2_1:2_260,Kka2,kka2_1:2,P00552,0.314068,NO,260,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.741,-2.914,2.173,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.295029,0.0233782,0.314068 beta-lactamase_156_M67K,beta-lactamase_156_67,TEM-1,beta-lactamase_156,P62593,0.314086,NO,67,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-2.231,-3.7,1.469,,0.006,G,P,0.55,-0.81,1.463,,65.03,HHP,-1.502,0.111618,0.00409753,0.314086 kka2_1:2_D183C,kka2_1:2_183,Kka2,kka2_1:2,P00552,0.314117,NO,183,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.204,-5.235,4.031,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.295029,0.00426304,0.314117 beta-lactamase_156_L160W,beta-lactamase_156_160,TEM-1,beta-lactamase_156,P62593,0.314124,NO,160,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.977,-5.194,4.217,,0.022,,B,0.55,-0.6,1.095,,44.41,BHA,-0.936,0.111618,0.00193775,0.314124 kka2_1:1_W24Y,kka2_1:1_24,Kka2,kka2_1:1,P00552,0.314146,NO,24,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-1.779,-3.045,1.266,,0.477,E,B,0.47,-0.21,2.375,,56.06,AHH,-2.24467,0.520039,0.00631564,0.314146 beta-lactamase_2500_K232F,beta-lactamase_2500_232,TEM-1,beta-lactamase_2500,P62593,0.314158,NO,232,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.012,-4.334,3.322,,,E,B,2.34,-1.1,3.048,,65.03,ABP,-1.238,0.361275,0.00313441,0.314158 beta-lactamase_2500_A132P,beta-lactamase_2500_132,TEM-1,beta-lactamase_2500,P62593,0.314332,NO,132,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.9,-3.725,2.825,,,H,A,0.46,-0.93,8.408,,64.69,PHH,-1.138,0.361275,0.000962524,0.314332 kka2_1:1_E235H,kka2_1:1_235,Kka2,kka2_1:1,P00552,0.314345,NO,235,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.955,-4.699,2.744,,0.631,H,A,1.52,0.12,8.521,,65.53,OAH,-2.07267,0.520039,0.0102806,0.314345 kka2_1:2_Y257L,kka2_1:2_257,Kka2,kka2_1:2,P00552,0.314413,NO,257,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-1.064,-3.141,2.077,,0.022,H,A,0.21,-0.88,0.833,,52.65,HHB,-1.39333,0.295029,0.0148191,0.314413 kka2_1:1_A117K,kka2_1:1_117,Kka2,kka2_1:1,P00552,0.314427,NO,117,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.828,-3.549,2.721,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.520039,0.00282984,0.314427 beta-lactamase_625_D161L,beta-lactamase_625_161,TEM-1,beta-lactamase_625,P62593,0.314429,NO,161,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.891,-3.777,2.886,,0.341,,A,0.75,-0.52,4.655,,61.19,HAB,-0.961333,0.213352,0.000897697,0.314429 beta-lactamase_156_C121D,beta-lactamase_156_121,TEM-1,beta-lactamase_156,P62593,0.314463,NO,121,C,D,CD,Special,negativeCharge,5.07,5.0516,-0.0184,154,121,133,12,108.5,111.1,2.6,-0.953,-3.916,2.963,,,H,A,0.46,-0.81,1.136,,63.29,HOP,-1.46767,0.111618,0.000744322,0.314463 Pab1_I152F,Pab1_152,Pab1,Pab1,P04147,0.314476,NO,152,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.345,-3.578,2.233,,0.165,E,B,1.23,-0.71,1.288,,71.4,AHH,-1.59433,0.175299,0.000740963,0.314476 Ubiquitin_F4P,Ubiquitin_4,Uba1,Ubiquitin,P0CG48,0.314516,NO,4,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.534,-4.125,2.591,4.77459,0.059,E,B,,-0.46,,,,HHH,-1.504,0.205827,0.000805043,0.314516 Ubiquitin_G75Q,Ubiquitin_75,Uba1,Ubiquitin,P0CG48,0.314516,NO,75,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.613,-4.074,2.461,5.44099,0.552,T,A,0.73,0.9,4.017,,34.31,BOO,-1.66767,0.205827,0.000712673,0.314516 Ubiquitin_I44A,Ubiquitin_44,Uba1,Ubiquitin,P0CG48,0.314516,NO,44,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.566,-2.512,0.946,4.71256,,E,B,0.27,-1.17,5.26,,39.71,HHH,-1.38567,0.205827,0.000613305,0.314516 Ubiquitin_K27L,Ubiquitin_27,Uba1,Ubiquitin,P0CG48,0.314516,NO,27,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.064,-3.406,2.342,4.77438,0.086,H,A,2.89,-0.74,2.662,,27.01,HBH,-1.42667,0.205827,0.000767556,0.314516 kka2_1:1_V214H,kka2_1:1_214,Kka2,kka2_1:1,P00552,0.314525,NO,214,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.261,-5.011,3.75,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.520039,0.00692782,0.314525 kka2_1:2_W91E,kka2_1:2_91,Kka2,kka2_1:2,P00552,0.314531,NO,91,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-1.178,-3.842,2.664,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.295029,0.00358653,0.314531 beta-lactamase_39_L205R,beta-lactamase_39_205,TEM-1,beta-lactamase_39,P62593,0.314585,NO,205,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.922,-3.987,3.065,,,H,A,0.55,-0.46,0.846,,42.31,PHH,-1.57767,0.0495842,0.00255802,0.314585 beta-lactamase_39_L74D,beta-lactamase_39_74,TEM-1,beta-lactamase_39,P62593,0.3146,NO,74,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.296,-4.023,2.727,,,H,A,0.55,-0.91,1.581,,50,HHO,-1.34933,0.0495842,0.00493255,0.3146 kka2_1:1_V83P,kka2_1:1_83,Kka2,kka2_1:1,P00552,0.314636,NO,83,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-2.567,-4.134,1.567,,0.358,E,B,0.44,0.53,5.931,,71.59,AHH,-2.264,0.520039,0.00650486,0.314636 kka2_1:1_F171C,kka2_1:1_171,Kka2,kka2_1:1,P00552,0.314734,NO,171,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.326,-4.966,3.64,,0.154,H,A,1.62,-0.1,13.679,13.679,63.64,HHH,-1.45433,0.520039,0.00821426,0.314734 beta-lactamase_625_G249N,beta-lactamase_625_249,TEM-1,beta-lactamase_625,P62593,0.314738,NO,249,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.213352,0.00220169,0.314738 kka2_1:1_A108Y,kka2_1:1_108,Kka2,kka2_1:1,P00552,0.314775,NO,108,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.061,-4.432,2.371,,0.243,.,B,0.46,-1.34,3.156,,71.59,HHO,-1.57033,0.520039,0.00751209,0.314775 kka2_1:2_Y22W,kka2_1:2_22,Kka2,kka2_1:2,P00552,0.314782,NO,22,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-1.583,-4.944,3.361,,0.122,.,B,0.21,-0.8,1.838,,65.53,OHA,-1.80333,0.295029,0.00598977,0.314782 beta-lactamase_2500_A132Q,beta-lactamase_2500_132,TEM-1,beta-lactamase_2500,P62593,0.314791,NO,132,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.9,-3.943,3.043,,,H,A,0.46,-0.93,8.408,,64.69,PHH,-1.138,0.361275,0.000962524,0.314791 kka2_1:4_F203D,kka2_1:4_203,Kka2,kka2_1:4,P00552,0.314823,NO,203,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-0.911,-4.011,3.1,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.168804,0.00318738,0.314823 PSD95pdz3_G330K,PSD95pdz3_330,PSD95pdz3,PSD95pdz3,P31016,0.314823,NO,330,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.008,-3.364,2.356,4.68351,,,,,31.405,,,,OOA,-1.14,0.0758425,0.000962386,0.314823 beta-lactamase_W227G,beta-lactamase_227,TEM-1,beta-lactamase,P62593,0.314824,NO,227,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-0.982,-2.451,1.469,4.86393,0.272,,B,0.99,-0.29,1.37,,74.48,OHH,-1.595,0.221079,0.00226019,0.314824 kka2_1:1_E235L,kka2_1:1_235,Kka2,kka2_1:1,P00552,0.31483,NO,235,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.955,-3.621,1.666,,0.631,H,A,1.52,0.12,8.521,,65.53,OAH,-2.07267,0.520039,0.0102806,0.31483 beta-lactamase_156_L146D,beta-lactamase_156_146,TEM-1,beta-lactamase_156,P62593,0.314832,NO,146,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.462,-4.108,2.646,,0.007,H,A,0.55,-0.56,1.578,,64.69,AHP,-1.656,0.111618,0.00474542,0.314832 beta-lactamase_2500_L191S,beta-lactamase_2500_191,TEM-1,beta-lactamase_2500,P62593,0.314894,NO,191,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.087,-3.562,2.475,,,H,A,0.55,0.09,1.703,,63.29,BHH,-1.445,0.361275,0.00263549,0.314894 kka2_1:1_D220N,kka2_1:1_220,Kka2,kka2_1:1,P00552,0.314905,NO,220,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.787,-3.336,2.549,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.520039,0.00158066,0.314905 kka2_1:4_C131L,kka2_1:4_131,Kka2,kka2_1:4,P00552,0.314917,NO,131,C,L,CL,Special,Hydrophobic,5.07,9.7088,4.6388,198,121,131,10,108.5,166.7,58.2,-0.831,-3.161,2.33,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.168804,0.00170814,0.314917 hsp90_M589D,hsp90_589,hsp90,hsp90,P02829,0.314965,NO,589,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-3.858,-2.847,0,4.72723,0.032,H,A,0.84,0.31,,,,PHA,-3.24233,0.368192,0.000222939,0.314965 kka2_1:2_D159A,kka2_1:2_159,Kka2,kka2_1:2,P00552,0.314989,NO,159,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.82,-3.286,2.466,,0.28,.,B,0.75,1.25,0.899,,48.11,HAA,-1.48333,0.295029,0.0030485,0.314989 beta-lactamase_625_V101P,beta-lactamase_625_101,TEM-1,beta-lactamase_625,P62593,0.314995,NO,101,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.295,-4.04,2.745,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.213352,0.00374492,0.314995 kka2_1:1_A108Q,kka2_1:1_108,Kka2,kka2_1:1,P00552,0.314999,NO,108,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.061,-3.285,1.224,,0.243,.,B,0.46,-1.34,3.156,,71.59,HHO,-1.57033,0.520039,0.00751209,0.314999 hsp90_A587V,hsp90_587,hsp90,hsp90,P02829,0.315058,NO,587,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.456,-2.682,0,4.91216,0.049,H,A,0.55,-0.02,,,,PHP,-2.757,0.368192,0.000222939,0.315058 kka2_1:8_K112N,kka2_1:8_112,Kka2,kka2_1:8,P00552,0.315073,NO,112,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-2.491,-3.976,1.485,,0.076,H,A,1.3,-1.37,10.58,10.58,56.06,ABH,-2.00133,0.100394,0.00645389,0.315073 kka2_1:8_K112N,kka2_1:8_112,Kka2,kka2_1:8,P00552,0.315073,NO,112,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-2.491,-3.976,1.485,,0.076,H,A,1.3,-1.37,10.58,10.58,56.06,ABH,-2.00133,0.100394,0.00645389,0.315073 beta-lactamase_625_I277N,beta-lactamase_625_277,TEM-1,beta-lactamase_625,P62593,0.315127,NO,277,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.213352,0.0169305,0.315127 kka2_1:4_V83P,kka2_1:4_83,Kka2,kka2_1:4,P00552,0.315139,NO,83,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-2.567,-4.134,1.567,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.168804,0.00650486,0.315139 kka2_1:2_L39K,kka2_1:2_39,Kka2,kka2_1:2,P00552,0.315186,NO,39,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.223,-3.871,2.648,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.295029,0.00493618,0.315186 kka2_1:2_A119M,kka2_1:2_119,Kka2,kka2_1:2,P00552,0.315187,NO,119,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.073,-4.566,3.493,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.295029,0.00441074,0.315187 kka2_1:8_I115R,kka2_1:8_115,Kka2,kka2_1:8,P00552,0.315205,NO,115,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.606,-4.203,2.597,,0.105,H,A,1.52,-1.18,4.064,,65.53,PHH,-2.205,0.100394,0.00836567,0.315205 kka2_1:8_I115R,kka2_1:8_115,Kka2,kka2_1:8,P00552,0.315205,NO,115,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.606,-4.203,2.597,,0.105,H,A,1.52,-1.18,4.064,,65.53,PHH,-2.205,0.100394,0.00836567,0.315205 kka2_1:1_F133M,kka2_1:1_133,Kka2,kka2_1:1,P00552,0.315213,NO,133,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-0.871,-4.327,3.456,,0.178,.,B,0.58,0.43,1.999,,42.42,OHA,-0.871667,0.520039,0.00182168,0.315213 beta-lactamase_G76H,beta-lactamase_76,TEM-1,beta-lactamase,P62593,0.315239,NO,76,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.189,-4.754,3.565,4.73862,,H,A,2.05,-0.67,3.059,,67.83,OOH,-1.22267,0.221079,0.00476637,0.315239 kka2_1:1_L260G,kka2_1:1_260,Kka2,kka2_1:1,P00552,0.315288,NO,260,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.741,-3.836,3.095,,0.022,H,A,0.55,-0.52,,,,HHA,-0.845667,0.520039,0.0233782,0.315288 beta-lactamase_0_D83V,beta-lactamase_0_83,TEM-1,beta-lactamase_0,P62593,0.315344,NO,83,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.066,-3.762,2.696,,0.354,H,A,0.75,0.22,0.617,,48.95,HAH,-1.34733,0.0500837,0.00205968,0.315344 kka2_1:1_R239A,kka2_1:1_239,Kka2,kka2_1:1,P00552,0.315396,NO,239,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.949,-2.185,-0.764,,0.15,H,A,1.2,-0.31,0.477,,71.59,ABH,-2.23,0.520039,0.00835326,0.315396 kka2_1:1_R239N,kka2_1:1_239,Kka2,kka2_1:1,P00552,0.315396,NO,239,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.949,-3.912,0.963,,0.15,H,A,1.2,-0.31,0.477,,71.59,ABH,-2.23,0.520039,0.00835326,0.315396 kka2_1:1_D82I,kka2_1:1_82,Kka2,kka2_1:1,P00552,0.31541,NO,82,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.946,-4.04,2.094,,0.341,E,b,0.75,0.52,11.345,11.345,63.64,HAH,-1.98,0.520039,0.00637516,0.31541 beta-lactamase_156_A235P,beta-lactamase_156_235,TEM-1,beta-lactamase_156,P62593,0.315534,NO,235,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.266,-3.821,2.555,,0.32,E,B,0.46,-0.86,1.344,,50,OHO,-0.89,0.111618,0.00493474,0.315534 kka2_1:1_A65L,kka2_1:1_65,Kka2,kka2_1:1,P00552,0.315563,NO,65,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.744,-2.62,0.876,,0.437,H,A,0.46,-0.39,3.012,,63.64,HHB,-1.38733,0.520039,0.00709258,0.315563 beta-lactamase_2500_K232N,beta-lactamase_2500_232,TEM-1,beta-lactamase_2500,P62593,0.315579,NO,232,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.012,-3.49,2.478,,,E,B,2.34,-1.1,3.048,,65.03,ABP,-1.238,0.361275,0.00313441,0.315579 kka2_1:2_A229W,kka2_1:2_229,Kka2,kka2_1:2,P00552,0.315605,NO,229,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.739,-5.507,3.768,,0.32,H,A,0.46,-0.7,6.549,,63.64,HHA,-1.851,0.295029,0.00942138,0.315605 kka2_1:1_Q252N,kka2_1:1_252,Kka2,kka2_1:1,P00552,0.315653,NO,252,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.63,-3.762,1.132,,0.906,H,A,0.64,0.35,1.369,,92.05,PPB,-2.20733,0.520039,0.0121001,0.315653 beta-lactamase_156_M66P,beta-lactamase_156_66,TEM-1,beta-lactamase_156,P62593,0.31566,NO,66,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.362,-4.047,2.685,,0.013,,A,0.55,-0.7,1.94,,73.08,OHH,-1.49567,0.111618,0.00412876,0.31566 kka2_1:1_R143Y,kka2_1:1_143,Kka2,kka2_1:1,P00552,0.315662,NO,143,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.525,-4.353,1.828,,0.325,H,A,0.16,1.22,3.6,,65.53,ABH,-1.86833,0.520039,0.00662247,0.315662 beta-lactamase_L146H,beta-lactamase_146,TEM-1,beta-lactamase,P62593,0.315709,NO,146,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.462,-4.92,3.458,5.62483,0.007,H,A,1.3,-0.56,1.953,,64.69,AHP,-1.656,0.221079,0.00474542,0.315709 kka2_1:4_A144F,kka2_1:4_144,Kka2,kka2_1:4,P00552,0.31573,NO,144,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.859,-4.095,3.236,,,H,A,0.46,0.21,6.844,,52.65,BHB,-1.72933,0.168804,0.00231095,0.31573 kka2_1:4_A144H,kka2_1:4_144,Kka2,kka2_1:4,P00552,0.31573,NO,144,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.859,-4.791,3.932,,,H,A,0.46,0.21,6.844,,52.65,BHB,-1.72933,0.168804,0.00231095,0.31573 kka2_1:4_L107R,kka2_1:4_107,Kka2,kka2_1:4,P00552,0.315766,NO,107,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.238,-4.11,2.872,,0.197,.,B,0.55,-1.1,0.398,,71.59,BHH,-2.143,0.168804,0.00561937,0.315766 kka2_1:4_L158D,kka2_1:4_158,Kka2,kka2_1:4,P00552,0.315804,NO,158,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.947,-4.014,2.067,,0.095,,B,1.59,0.77,7.588,,63.64,AHA,-1.25333,0.168804,0.00529068,0.315804 beta-lactamase_156_D155M,beta-lactamase_156_155,TEM-1,beta-lactamase_156,P62593,0.315835,NO,155,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.889,-4.929,4.04,,0.049,,B,0.75,-0.9,0.315,,64.69,OAB,-1.62267,0.111618,0.00135315,0.315835 kka2_1:1_L103C,kka2_1:1_103,Kka2,kka2_1:1,P00552,0.315848,NO,103,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-2.362,-4.794,2.432,,0.394,T,A,0.55,-0.99,4.121,,63.64,HHP,-1.534,0.520039,0.00574792,0.315848 beta-lactamase_2500_G39P,beta-lactamase_2500_39,TEM-1,beta-lactamase_2500,P62593,0.315867,NO,39,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.864,-3.073,1.209,,0.701,T,L,0.29,0.47,29.926,29.926,77.62,HOH,-1.53633,0.361275,0.00487611,0.315867 beta-lactamase_0_T126R,beta-lactamase_0_126,TEM-1,beta-lactamase_0,P62593,0.315941,NO,126,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.122,-3.84,2.718,,0.05,H,A,0.22,-0.05,0.705,,44.41,HPH,-1.60467,0.0500837,0.00244552,0.315941 kka2_1:1_P76C,kka2_1:1_76,Kka2,kka2_1:1,P00552,0.315941,NO,76,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.449,-5.046,3.597,,0.331,.,B,0.52,-0.41,0.345,,63.64,HOO,-1.662,0.520039,0.00625685,0.315941 PSD95pdz3_A347H,PSD95pdz3_347,PSD95pdz3,PSD95pdz3,P31016,0.316007,NO,347,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.307,-4.362,3.055,4.89689,,,,,15.176,,,,OHA,-1.269,0.0758425,0.00074525,0.316007 kka2_1:1_G151M,kka2_1:1_151,Kka2,kka2_1:1,P00552,0.316014,NO,151,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.873,-4.939,4.066,,0.678,T,l,0.29,1.36,0.226,,49.62,HOH,-1.11433,0.520039,0.00339918,0.316014 kka2_1:2_F263E,kka2_1:2_263,Kka2,kka2_1:2,P00552,0.316014,NO,263,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-0.911,-3.952,3.041,,0.006,G,A,1.62,-0.12,5.275,,45.83,AHH,-0.92,0.295029,0.0172454,0.316014 kka2_1:2_F263H,kka2_1:2_263,Kka2,kka2_1:2,P00552,0.316014,NO,263,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-0.911,-4.571,3.66,,0.006,G,A,1.62,-0.12,5.275,,45.83,AHH,-0.92,0.295029,0.0172454,0.316014 beta-lactamase_P143W,beta-lactamase_143,TEM-1,beta-lactamase,P62593,0.31603,NO,143,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.967,-5.497,4.53,5.16366,0.075,H,A,0.99,-0.37,0.479,,66.78,OOB,-1.354,0.221079,0.00114551,0.31603 kka2_1:1_F256H,kka2_1:1_256,Kka2,kka2_1:1,P00552,0.316086,NO,256,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.49,-4.32,2.83,,,H,A,1.62,-0.78,2.354,,53.03,HHH,-1.423,0.520039,0.0132841,0.316086 kka2_1:2_F264T,kka2_1:2_264,Kka2,kka2_1:2,P00552,0.31611,NO,264,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.02,-3.729,2.709,,0.296,.,?,0.58,0.02,2.303,,71.59,HHNA,-0.9655,0.295029,,0.31611 kka2_1:8_N195M,kka2_1:8_195,Kka2,kka2_1:8,P00552,0.31613,NO,195,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-0.836,-4.777,3.941,,0.037,G,A,0.43,-1.36,1.108,,48.11,OPH,-1.26567,0.100394,0.00276134,0.31613 kka2_1:8_N195M,kka2_1:8_195,Kka2,kka2_1:8,P00552,0.31613,NO,195,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-0.836,-4.777,3.941,,0.037,G,A,0.43,-1.36,1.108,,48.11,OPH,-1.26567,0.100394,0.00276134,0.31613 kka2_1:1_Q100G,kka2_1:1_100,Kka2,kka2_1:1,P00552,0.316179,NO,100,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.77,-3.044,0.274,,0.646,E,B,0.4,-0.79,15.116,15.116,71.59,OPA,-1.46467,0.520039,0.0066405,0.316179 kka2_1:1_M178E,kka2_1:1_178,Kka2,kka2_1:1,P00552,0.316186,NO,178,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-3.206,-3.572,0.366,,0.554,.,b,0.55,0.68,3.152,,71.59,BHO,-2.154,0.520039,0.00717253,0.316186 beta-lactamase_625_L284D,beta-lactamase_625_284,TEM-1,beta-lactamase_625,P62593,0.316221,NO,284,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.213352,0.0686156,0.316221 beta-lactamase_2500_A123L,beta-lactamase_2500_123,TEM-1,beta-lactamase_2500,P62593,0.316258,NO,123,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.834,-3.096,2.262,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.361275,0.0010157,0.316258 beta-lactamase_625_L79E,beta-lactamase_625_79,TEM-1,beta-lactamase_625,P62593,0.316309,NO,79,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.842,-3.887,3.045,,0.007,H,A,0.55,-0.16,0.935,,50.35,HHP,-1.44333,0.213352,0.000947397,0.316309 kka2_1:2_G201I,kka2_1:2_201,Kka2,kka2_1:2,P00552,0.316352,NO,201,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.56,-4.262,2.702,,0.149,T,l,0.29,-0.57,16.092,16.092,52.65,POB,-1.92233,0.295029,0.00820117,0.316352 kka2_1:1_A176L,kka2_1:1_176,Kka2,kka2_1:1,P00552,0.316375,NO,176,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.621,-3.555,1.934,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.520039,0.0083587,0.316375 kka2_1:1_A255R,kka2_1:1_255,Kka2,kka2_1:1,P00552,0.316402,NO,255,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.715,-2.777,1.062,,0.466,H,A,0.46,-0.52,0.946,,65.53,HHH,-1.71267,0.520039,0.0126809,0.316402 kka2_1:2_L107D,kka2_1:2_107,Kka2,kka2_1:2,P00552,0.316404,NO,107,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.238,-3.01,1.772,,0.197,,B,1.59,-1.1,2.68,,71.59,BHH,-2.143,0.295029,0.00561937,0.316404 kka2_1:2_F256T,kka2_1:2_256,Kka2,kka2_1:2,P00552,0.316433,NO,256,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.49,-3.783,2.293,,,H,A,0.58,-0.78,1.653,,53.03,HHH,-1.423,0.295029,0.0132841,0.316433 beta-lactamase_39_W227N,beta-lactamase_39_227,TEM-1,beta-lactamase_39,P62593,0.31647,NO,227,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-0.982,-4.236,3.254,,0.272,,B,0.47,-0.29,1.37,,74.48,OHH,-1.595,0.0495842,0.00226019,0.31647 kka2_1:4_Q219Y,kka2_1:4_219,Kka2,kka2_1:4,P00552,0.31651,NO,219,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-0.93,-4.01,3.08,,0.088,H,A,0.64,-0.85,1.537,,50,HPA,-1.05167,0.168804,0.00237913,0.31651 beta-lactamase_625_W288N,beta-lactamase_625_288,TEM-1,beta-lactamase_625,P62593,0.316607,NO,288,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,,,,,,,,,,,,,BHO,,0.213352,,0.316607 kka2_1:1_R202E,kka2_1:1_202,Kka2,kka2_1:1,P00552,0.316647,NO,202,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.761,-2.596,0.835,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.520039,0.00696498,0.316647 kka2_1:4_R258E,kka2_1:4_258,Kka2,kka2_1:4,P00552,0.31665,NO,258,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.626,-2.838,1.212,,0.316,H,A,1.2,-0.85,2.655,,53.03,HBH,-1.25933,0.168804,0.00983174,0.31665 beta-lactamase_A34D,beta-lactamase_34,TEM-1,beta-lactamase,P62593,0.316677,NO,34,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.059,-3.876,1.817,4.9129,,H,A,0.75,-0.54,3.614,,73.78,AHA,-1.74967,0.221079,0.00407913,0.316677 beta-lactamase_625_D174K,beta-lactamase_625_174,TEM-1,beta-lactamase_625,P62593,0.316721,NO,174,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.738,-3.457,2.719,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.213352,0.00125633,0.316721 PSD95pdz3_A347Y,PSD95pdz3_347,PSD95pdz3,PSD95pdz3,P31016,0.316755,NO,347,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.307,-3.844,2.537,4.89689,,,,,15.176,,,,OHA,-1.269,0.0758425,0.00074525,0.316755 hsp90_A587Q,hsp90_587,hsp90,hsp90,P02829,0.31678,NO,587,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.456,-3.278,0,4.91216,0.049,H,A,0.55,-0.02,,,,PHP,-2.757,0.368192,0.000222939,0.31678 kka2_1:4_L107S,kka2_1:4_107,Kka2,kka2_1:4,P00552,0.31679,NO,107,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.238,-3.641,2.403,,0.197,.,B,0.55,-1.1,0.398,,71.59,BHH,-2.143,0.168804,0.00561937,0.31679 kka2_1:4_L212F,kka2_1:4_212,Kka2,kka2_1:4,P00552,0.316843,NO,212,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.904,-3.768,2.864,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.168804,0.0031426,0.316843 kka2_1:2_V214H,kka2_1:2_214,Kka2,kka2_1:2,P00552,0.316866,NO,214,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.261,-5.011,3.75,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.295029,0.00692782,0.316866 kka2_1:1_R217Y,kka2_1:1_217,Kka2,kka2_1:1,P00552,0.316891,NO,217,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.158,-4.252,3.094,,0.252,T,A,1.2,-0.59,0.381,,52.27,ABH,-1.127,0.520039,0.0047191,0.316891 kka2_1:1_R44V,kka2_1:1_44,Kka2,kka2_1:1,P00552,0.316894,NO,44,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.062,-3.733,1.671,,0.487,S,B,1.2,-0.35,2.717,,71.59,OBO,-1.80767,0.520039,0.00745043,0.316894 kka2_1:2_G151Y,kka2_1:2_151,Kka2,kka2_1:2,P00552,0.316916,NO,151,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.873,-4.442,3.569,,0.678,T,l,0.29,1.36,1.357,,49.62,HOH,-1.11433,0.295029,0.00339918,0.316916 kka2_1:4_L170C,kka2_1:4_170,Kka2,kka2_1:4,P00552,0.316955,NO,170,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.28,-4.755,3.475,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.168804,0.00730791,0.316955 kka2_1:4_A215F,kka2_1:4_215,Kka2,kka2_1:4,P00552,0.316974,NO,215,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.968,-4.18,3.212,,0.039,E,B,0.46,-0.59,0.754,,50.38,HHA,-1.00467,0.168804,0.00529129,0.316974 kka2_1:4_V113H,kka2_1:4_113,Kka2,kka2_1:4,P00552,0.316989,NO,113,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.233,-5.033,3.8,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.168804,0.00650191,0.316989 kka2_1:1_A176Y,kka2_1:1_176,Kka2,kka2_1:1,P00552,0.317004,NO,176,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.621,-4.408,2.787,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.520039,0.0083587,0.317004 beta-lactamase_2500_L100H,beta-lactamase_2500_100,TEM-1,beta-lactamase_2500,P62593,0.317038,NO,100,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.218,-4.855,3.637,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.361275,0.00413885,0.317038 kka2_1:8_G205H,kka2_1:8_205,Kka2,kka2_1:8,P00552,0.317052,NO,205,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.596,-4.708,4.112,,,E,b,0.75,-1.05,,,,POH,-1.09933,0.100394,0.00221855,0.317052 kka2_1:8_G205H,kka2_1:8_205,Kka2,kka2_1:8,P00552,0.317052,NO,205,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.596,-4.708,4.112,,,E,b,0.75,-1.05,,,,POH,-1.09933,0.100394,0.00221855,0.317052 beta-lactamase_156_P65W,beta-lactamase_156_65,TEM-1,beta-lactamase_156,P62593,0.31708,NO,65,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.894,-5.47,4.576,,0.098,E,B,0.52,-0.62,0.623,,40.56,HOH,-1.03233,0.111618,0.00152776,0.31708 kka2_1:2_L126Q,kka2_1:2_126,Kka2,kka2_1:2,P00552,0.317107,NO,126,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.246,-3.15,1.904,,0.285,S,B,0.55,0.12,1.392,,51.89,PHA,-1.744,0.295029,0.0066485,0.317107 Pab1_A182N,Pab1_182,Pab1,Pab1,P04147,0.317124,NO,182,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.013,-3.715,2.702,,,H,A,0.17,0.79,,,,AHH,-1.36067,0.175299,0.000289034,0.317124 kka2_1:2_L70F,kka2_1:2_70,Kka2,kka2_1:2,P00552,0.317127,NO,70,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.017,-3.762,2.745,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.295029,0.00411884,0.317127 beta-lactamase_156_M153P,beta-lactamase_156_153,TEM-1,beta-lactamase_156,P62593,0.317159,NO,153,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-3.193,-4.07,0.877,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.111618,0.00509109,0.317159 beta-lactamase_625_P224I,beta-lactamase_625_224,TEM-1,beta-lactamase_625,P62593,0.317213,NO,224,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.893,-4.034,3.141,,0.383,,B,0.52,-0.3,1.35,,74.48,HOH,-1.26433,0.213352,0.00189564,0.317213 Pab1_F129C,Pab1_129,Pab1,Pab1,P04147,0.317235,NO,129,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.269,-4.733,3.464,,0.219,E,B,0.03,-0.07,1.307,,73.83,HHH,-1.27533,0.175299,0.000625182,0.317235 beta-lactamase_625_R257F,beta-lactamase_625_257,TEM-1,beta-lactamase_625,P62593,0.317236,NO,257,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.213352,0.00756629,0.317236 kka2_1:1_A215N,kka2_1:1_215,Kka2,kka2_1:1,P00552,0.317255,NO,215,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.968,-3.769,2.801,,0.039,E,B,0.46,-0.59,0.754,,50.38,HHA,-1.00467,0.520039,0.00529129,0.317255 beta-lactamase_W227V,beta-lactamase_227,TEM-1,beta-lactamase,P62593,0.317269,NO,227,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-0.982,-3.747,2.765,4.86393,0.272,,B,0.99,-0.29,1.37,,74.48,OHH,-1.595,0.221079,0.00226019,0.317269 kka2_1:8_Y244P,kka2_1:8_244,Kka2,kka2_1:8,P00552,0.317315,NO,244,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-0.775,-4.133,3.358,,0.066,H,A,1.25,-0.64,,,,HHO,-1.41267,0.100394,0.00453187,0.317315 kka2_1:8_Y244P,kka2_1:8_244,Kka2,kka2_1:8,P00552,0.317315,NO,244,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-0.775,-4.133,3.358,,0.066,H,A,1.25,-0.64,,,,HHO,-1.41267,0.100394,0.00453187,0.317315 beta-lactamase_625_D177I,beta-lactamase_625_177,TEM-1,beta-lactamase_625,P62593,0.317327,NO,177,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.967,-4.048,3.081,,0.006,T,L,0.75,-1.02,1.333,,64.69,BAP,-0.873667,0.213352,0.000864022,0.317327 beta-lactamase_2500_L79Q,beta-lactamase_2500_79,TEM-1,beta-lactamase_2500,P62593,0.317438,NO,79,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.842,-4.087,3.245,,0.007,H,A,0.55,-0.16,0.823,,50.35,HHP,-1.44333,0.361275,0.000947397,0.317438 kka2_1:8_R253D,kka2_1:8_253,Kka2,kka2_1:8,P00552,0.317446,NO,253,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.356,-3.762,2.406,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.100394,0.0144195,0.317446 kka2_1:8_R253D,kka2_1:8_253,Kka2,kka2_1:8,P00552,0.317446,NO,253,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.356,-3.762,2.406,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.100394,0.0144195,0.317446 kka2_1:2_L212N,kka2_1:2_212,Kka2,kka2_1:2,P00552,0.31749,NO,212,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.904,-4.173,3.269,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.295029,0.0031426,0.31749 kka2_1:1_E63N,kka2_1:1_63,Kka2,kka2_1:1,P00552,0.317506,NO,63,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-0.762,-3.476,2.714,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.520039,0.00118399,0.317506 beta-lactamase_625_T116W,beta-lactamase_625_116,TEM-1,beta-lactamase_625,P62593,0.317576,NO,116,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.28,-5.356,4.076,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.213352,0.00336175,0.317576 beta-lactamase_625_M115D,beta-lactamase_625_115,TEM-1,beta-lactamase_625,P62593,0.317586,NO,115,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.389,-4.023,2.634,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.213352,0.0034337,0.317586 beta-lactamase_2500_K232I,beta-lactamase_2500_232,TEM-1,beta-lactamase_2500,P62593,0.317614,NO,232,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.012,-4.053,3.041,,,E,B,2.34,-1.1,3.048,,65.03,ABP,-1.238,0.361275,0.00313441,0.317614 beta-lactamase_2500_M115N,beta-lactamase_2500_115,TEM-1,beta-lactamase_2500,P62593,0.317688,NO,115,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.389,-4.013,2.624,,0.019,E,B,0.55,0.08,3.261,,69.58,OHP,-1.25433,0.361275,0.0034337,0.317688 beta-lactamase_156_L136Q,beta-lactamase_156_136,TEM-1,beta-lactamase_156,P62593,0.317735,NO,136,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.232,-4.242,3.01,,,H,A,0.55,-0.34,1.04,,48.95,HHH,-1.088,0.111618,0.00442304,0.317735 beta-lactamase_2500_E46R,beta-lactamase_2500_46,TEM-1,beta-lactamase_2500,P62593,0.317787,NO,46,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.94,-4.04,2.1,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.361275,0.00427568,0.317787 kka2_1:1_D127I,kka2_1:1_127,Kka2,kka2_1:1,P00552,0.317841,NO,127,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.364,-4.127,2.763,,0.573,.,B,0.75,0.45,3.414,,50.38,HAO,-1.51067,0.520039,0.00660501,0.317841 kka2_1:1_D154N,kka2_1:1_154,Kka2,kka2_1:1,P00552,0.317924,NO,154,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.876,-2.341,1.465,,0.457,.,b,0.75,1.48,0.658,,52.65,HAP,-1.52467,0.520039,0.00292633,0.317924 kka2_1:2_R140V,kka2_1:2_140,Kka2,kka2_1:2,P00552,0.31796,NO,140,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.351,-3.736,2.385,,0.12,H,A,1.2,0.2,0.352,,53.03,BBH,-1.885,0.295029,0.00430167,0.31796 beta-lactamase_625_S128V,beta-lactamase_625_128,TEM-1,beta-lactamase_625,P62593,0.317988,NO,128,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-0.84,-3.529,2.689,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.213352,0.00071483,0.317988 kka2_1:1_A87F,kka2_1:1_87,Kka2,kka2_1:1,P00552,0.317995,NO,87,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.917,-4.449,2.532,,1.039,S,L,0.46,1.57,20.738,20.738,65.53,AHO,-1.822,0.520039,0.00791281,0.317995 beta-lactamase_625_T107Y,beta-lactamase_625_107,TEM-1,beta-lactamase_625,P62593,0.318012,NO,107,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.117,-4.214,3.097,,,G,A,0.22,-0.06,3.676,,67.83,HPA,-1.265,0.213352,0.00239347,0.318012 kka2_1:1_H188A,kka2_1:1_188,Kka2,kka2_1:1,P00552,0.318044,NO,188,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-0.913,-3.329,2.416,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.520039,0.00273139,0.318044 beta-lactamase_2500_V117Y,beta-lactamase_2500_117,TEM-1,beta-lactamase_2500,P62593,0.318061,NO,117,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.53,-2.958,1.428,,,H,A,0.44,-0.34,1.23,,65.03,PHB,-1.741,0.361275,0.00467906,0.318061 Pab1_L133W,Pab1_133,Pab1,Pab1,P04147,0.318076,NO,133,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.039,-4.915,3.876,,0.015,,B,1.75,1.03,,,,PHB,-1.22,0.175299,0.000345939,0.318076 beta-lactamase_625_E119I,beta-lactamase_625_119,TEM-1,beta-lactamase_625,P62593,0.31808,NO,119,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.412,-4.096,2.684,,0.358,H,A,1.04,0.51,1.034,,63.99,BAH,-1.623,0.213352,0.00386966,0.31808 kka2_1:1_A229P,kka2_1:1_229,Kka2,kka2_1:1,P00552,0.318114,NO,229,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.739,-3.997,2.258,,0.32,H,A,0.46,-0.7,6.549,,63.64,HHA,-1.851,0.520039,0.00942138,0.318114 beta-lactamase_M67Y,beta-lactamase_67,TEM-1,beta-lactamase,P62593,0.318137,NO,67,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-2.231,-4.282,2.051,4.9618,0.006,G,P,1.07,-0.81,1.463,,65.03,HHP,-1.502,0.221079,0.00409753,0.318137 kka2_1:1_V49T,kka2_1:1_49,Kka2,kka2_1:1,P00552,0.318168,NO,49,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.614,-3.462,1.848,,,E,B,0.44,-0.77,3.665,3.665,64.39,HHB,-1.3,0.520039,0.00615685,0.318168 kka2_1:2_A144C,kka2_1:2_144,Kka2,kka2_1:2,P00552,0.318187,NO,144,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.859,-4.523,3.664,,,H,A,0.46,0.21,6.844,,52.65,BHB,-1.72933,0.295029,0.00231095,0.318187 beta-lactamase_M66E,beta-lactamase_66,TEM-1,beta-lactamase,P62593,0.318246,NO,66,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.362,-3.832,2.47,5.29561,0.013,,A,1.3,-0.7,1.319,,73.08,OHH,-1.49567,0.221079,0.00412876,0.318246 beta-lactamase_2500_P65L,beta-lactamase_2500_65,TEM-1,beta-lactamase_2500,P62593,0.318258,NO,65,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.894,-2.247,1.353,,0.098,E,B,0.52,-0.62,0.3,,40.56,HOH,-1.03233,0.361275,0.00152776,0.318258 kka2_1:8_H188T,kka2_1:8_188,Kka2,kka2_1:8,P00552,0.318342,NO,188,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-0.913,-3.673,2.76,,0.006,,A,0.87,-1.02,1.241,,47.73,PBO,-0.927333,0.100394,0.00273139,0.318342 kka2_1:8_H188T,kka2_1:8_188,Kka2,kka2_1:8,P00552,0.318342,NO,188,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-0.913,-3.673,2.76,,0.006,,A,0.87,-1.02,1.241,,47.73,PBO,-0.927333,0.100394,0.00273139,0.318342 beta-lactamase_39_G43M,beta-lactamase_39_43,TEM-1,beta-lactamase_39,P62593,0.318352,NO,43,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.62,-4.93,4.31,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.0495842,0.00120151,0.318352 kka2_1:8_L102E,kka2_1:8_102,Kka2,kka2_1:8,P00552,0.318364,NO,102,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.804,-3.916,3.112,,,T,A,1.59,-1.17,0.97,,42.42,AHH,-1.398,0.100394,0.00201332,0.318364 kka2_1:8_L102E,kka2_1:8_102,Kka2,kka2_1:8,P00552,0.318364,NO,102,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.804,-3.916,3.112,,,T,A,1.59,-1.17,0.97,,42.42,AHH,-1.398,0.100394,0.00201332,0.318364 beta-lactamase_T178Y,beta-lactamase_178,TEM-1,beta-lactamase,P62593,0.318389,NO,178,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-0.791,-4.162,3.371,5.06452,0.029,E,B,0.3,-1.07,,,,APP,-0.947667,0.221079,0.000684366,0.318389 kka2_1:1_K112M,kka2_1:1_112,Kka2,kka2_1:1,P00552,0.318413,NO,112,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-2.491,-4.49,1.999,,0.076,H,A,2.34,-1.37,23.433,23.433,56.06,ABH,-2.00133,0.520039,0.00645389,0.318413 beta-lactamase_2500_R59G,beta-lactamase_2500_59,TEM-1,beta-lactamase_2500,P62593,0.318479,NO,59,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.345,-3.412,2.067,,0.329,S,L,1.2,-0.09,3.719,,73.08,HBO,-2.24267,0.361275,0.00318082,0.318479 kka2_1:1_D82K,kka2_1:1_82,Kka2,kka2_1:1,P00552,0.318484,NO,82,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.946,-3.004,1.058,,0.341,E,b,0.75,0.52,11.345,11.345,63.64,HAH,-1.98,0.520039,0.00637516,0.318484 kka2_1:1_W24I,kka2_1:1_24,Kka2,kka2_1:1,P00552,0.318508,NO,24,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-1.779,-2.156,0.377,,0.477,E,B,0.47,-0.21,2.375,,56.06,AHH,-2.24467,0.520039,0.00631564,0.318508 kka2_1:1_S204A,kka2_1:1_204,Kka2,kka2_1:1,P00552,0.318578,NO,204,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.353,-1.861,0.508,,0.144,E,A,0.27,-1.2,3.022,,65.53,HPO,-0.953333,0.520039,0.00881794,0.318578 kka2_1:1_G151S,kka2_1:1_151,Kka2,kka2_1:1,P00552,0.318591,NO,151,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.873,-2.614,1.741,,0.678,T,l,0.29,1.36,0.226,,49.62,HOH,-1.11433,0.520039,0.00339918,0.318591 kka2_1:1_V36N,kka2_1:1_36,Kka2,kka2_1:1,P00552,0.318591,NO,36,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-0.898,-4.196,3.298,,0.292,E,B,0.44,0.21,0.278,,52.27,HHH,-1.484,0.520039,0.00245633,0.318591 beta-lactamase_P181M,beta-lactamase_181,TEM-1,beta-lactamase,P62593,0.318602,NO,181,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.813,-4.702,3.889,5.14752,,H,A,1.1,-1.14,1.357,,61.54,HOH,-1.795,0.221079,0.000703122,0.318602 kka2_1:8_W236D,kka2_1:8_236,Kka2,kka2_1:8,P00552,0.318626,NO,236,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-1.363,-4.158,2.795,,0.303,H,A,1.51,-0.76,1.87,,48.48,AHH,-1.81267,0.100394,0.0088796,0.318626 kka2_1:8_W236D,kka2_1:8_236,Kka2,kka2_1:8,P00552,0.318626,NO,236,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-1.363,-4.158,2.795,,0.303,H,A,1.51,-0.76,1.87,,48.48,AHH,-1.81267,0.100394,0.0088796,0.318626 kka2_1:1_D90I,kka2_1:1_90,Kka2,kka2_1:1,P00552,0.318674,NO,90,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.459,-3.293,0.834,,0.104,E,B,0.75,0.73,6.085,,64.39,BAH,-1.72833,0.520039,0.00583842,0.318674 kka2_1:1_V49Y,kka2_1:1_49,Kka2,kka2_1:1,P00552,0.318674,NO,49,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.614,-4.126,2.512,,,E,B,0.44,-0.77,3.665,3.665,64.39,HHB,-1.3,0.520039,0.00615685,0.318674 kka2_1:1_P249V,kka2_1:1_249,Kka2,kka2_1:1,P00552,0.318675,NO,249,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.867,-2.403,0.536,,0.406,.,B,0.52,-0.01,8.037,8.037,92.05,HOA,-1.66867,0.520039,0.011045,0.318675 kka2_1:1_E199T,kka2_1:1_199,Kka2,kka2_1:1,P00552,0.31868,NO,199,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.234,-2.695,0.461,,0.508,E,B,1.04,-0.43,3.012,,65.53,HAP,-2.133,0.520039,0.00854122,0.31868 kka2_1:1_D183A,kka2_1:1_183,Kka2,kka2_1:1,P00552,0.318681,NO,183,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.204,-3.349,2.145,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.520039,0.00426304,0.318681 kka2_1:2_R44P,kka2_1:2_44,Kka2,kka2_1:2,P00552,0.318717,NO,44,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.062,-4.075,2.013,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.295029,0.00745043,0.318717 beta-lactamase_625_L191D,beta-lactamase_625_191,TEM-1,beta-lactamase_625,P62593,0.318767,NO,191,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.087,-4.092,3.005,,,H,A,0.55,0.09,1.908,,63.29,BHH,-1.445,0.213352,0.00263549,0.318767 kka2_1:4_G30P,kka2_1:4_30,Kka2,kka2_1:4,P00552,0.318778,NO,30,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.596,-3.908,3.312,,0.54,S,g,0.29,3.76,,,,HOO,-1.51133,0.168804,0.00159208,0.318778 beta-lactamase_I229Q,beta-lactamase_229,TEM-1,beta-lactamase,P62593,0.318813,NO,229,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.267,-4.304,3.037,5.0911,0.083,E,B,1,-0.76,1.114,,50,HHH,-1.58767,0.221079,0.00477249,0.318813 beta-lactamase_625_T131D,beta-lactamase_625_131,TEM-1,beta-lactamase_625,P62593,0.318905,NO,131,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.328,-3.605,2.277,,,H,A,0.22,-0.69,2.031,,67.48,PPH,-1.00867,0.213352,0.00345886,0.318905 kka2_1:4_Y257M,kka2_1:4_257,Kka2,kka2_1:4,P00552,0.318945,NO,257,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-1.064,-4.488,3.424,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.168804,0.0148191,0.318945 beta-lactamase_2500_H110P,beta-lactamase_2500_110,TEM-1,beta-lactamase_2500,P62593,0.318989,NO,110,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-1.706,-2.996,1.29,,0.341,G,a,0.17,1.08,31.31,31.31,64.69,BBH,-1.73333,0.361275,0.00441499,0.318989 kka2_1:2_P128H,kka2_1:2_128,Kka2,kka2_1:2,P00552,0.319023,NO,128,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.922,-4.964,3.042,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.295029,0.00774689,0.319023 beta-lactamase_156_R91P,beta-lactamase_156_91,TEM-1,beta-lactamase_156,P62593,0.319029,NO,91,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.392,-3.876,2.484,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.111618,0.00380226,0.319029 kka2_1:2_G205D,kka2_1:2_205,Kka2,kka2_1:2,P00552,0.319047,NO,205,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.596,-3.497,2.901,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.295029,0.00221855,0.319047 kka2_1:1_L241V,kka2_1:1_241,Kka2,kka2_1:1,P00552,0.319081,NO,241,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.158,-3.12,1.962,,0.08,H,A,0.55,-0.82,1.685,,63.26,HHH,-1.58533,0.520039,0.0117299,0.319081 kka2_1:2_L170A,kka2_1:2_170,Kka2,kka2_1:2,P00552,0.319113,NO,170,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.28,-2.219,0.939,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.295029,0.00730791,0.319113 kka2_1:1_R239Q,kka2_1:1_239,Kka2,kka2_1:1,P00552,0.319137,NO,239,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.949,-4.068,1.119,,0.15,H,A,1.2,-0.31,0.477,,71.59,ABH,-2.23,0.520039,0.00835326,0.319137 kka2_1:1_G164N,kka2_1:1_164,Kka2,kka2_1:1,P00552,0.319228,NO,164,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.869,-2.458,1.589,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.520039,0.00442091,0.319228 beta-lactamase_625_E119W,beta-lactamase_625_119,TEM-1,beta-lactamase_625,P62593,0.319261,NO,119,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.412,-5.452,4.04,,0.358,H,A,1.04,0.51,1.034,,63.99,BAH,-1.623,0.213352,0.00386966,0.319261 kka2_1:1_Y22R,kka2_1:1_22,Kka2,kka2_1:1,P00552,0.319262,NO,22,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-1.583,-3.13,1.547,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.520039,0.00598977,0.319262 kka2_1:1_M116H,kka2_1:1_116,Kka2,kka2_1:1,P00552,0.319289,NO,116,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-2.482,-4.918,2.436,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.520039,0.00745147,0.319289 kka2_1:4_I228E,kka2_1:4_228,Kka2,kka2_1:4,P00552,0.319318,NO,228,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.142,-3.95,2.808,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.168804,0.00458834,0.319318 kka2_1:1_E169F,kka2_1:1_169,Kka2,kka2_1:1,P00552,0.319319,NO,169,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.996,-3.429,1.433,,0.422,H,A,1.04,0.3,7.546,7.546,65.53,HAH,-1.755,0.520039,0.00730086,0.319319 kka2_1:1_D157Q,kka2_1:1_157,Kka2,kka2_1:1,P00552,0.319324,NO,157,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.993,-3.78,2.787,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.520039,0.0042313,0.319324 kka2_1:2_G201F,kka2_1:2_201,Kka2,kka2_1:2,P00552,0.319326,NO,201,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.56,-4.498,2.938,,0.149,T,l,0.29,-0.57,16.092,16.092,52.65,POB,-1.92233,0.295029,0.00820117,0.319326 kka2_1:4_A34M,kka2_1:4_34,Kka2,kka2_1:4,P00552,0.319382,NO,34,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.928,-4.54,3.612,,0.417,.,B,0.46,2.29,0.262,,52.27,AHH,-1.747,0.168804,0.00343484,0.319382 kka2_1:8_R217I,kka2_1:8_217,Kka2,kka2_1:8,P00552,0.319411,NO,217,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.158,-2.477,1.319,,0.252,T,A,0.16,-0.59,1.151,,52.27,ABH,-1.127,0.100394,0.0047191,0.319411 kka2_1:8_R217I,kka2_1:8_217,Kka2,kka2_1:8,P00552,0.319411,NO,217,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.158,-2.477,1.319,,0.252,T,A,0.16,-0.59,1.151,,52.27,ABH,-1.127,0.100394,0.0047191,0.319411 kka2_1:1_I115E,kka2_1:1_115,Kka2,kka2_1:1,P00552,0.319412,NO,115,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.606,-3.967,2.361,,0.105,H,A,0.48,-1.18,0.878,,65.53,PHH,-2.205,0.520039,0.00836567,0.319412 kka2_1:4_M120K,kka2_1:4_120,Kka2,kka2_1:4,P00552,0.319443,NO,120,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-3.877,-3.733,-0.144,,,H,A,0.55,-0.42,2.259,,92.05,HHB,-2.16733,0.168804,0.00265808,0.319443 kka2_1:4_F171G,kka2_1:4_171,Kka2,kka2_1:4,P00552,0.319488,NO,171,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.326,-3.793,2.467,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.168804,0.00821426,0.319488 kka2_1:2_N195Y,kka2_1:2_195,Kka2,kka2_1:2,P00552,0.319492,NO,195,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-0.836,-4.235,3.399,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.295029,0.00276134,0.319492 kka2_1:1_H188W,kka2_1:1_188,Kka2,kka2_1:1,P00552,0.319537,NO,188,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-0.913,-5.149,4.236,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.520039,0.00273139,0.319537 kka2_1:8_V97Y,kka2_1:8_97,Kka2,kka2_1:8,P00552,0.319541,NO,97,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.453,-4.124,2.671,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.100394,0.00737869,0.319541 kka2_1:8_V97Y,kka2_1:8_97,Kka2,kka2_1:8,P00552,0.319541,NO,97,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.453,-4.124,2.671,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.100394,0.00737869,0.319541 beta-lactamase_2500_L100E,beta-lactamase_2500_100,TEM-1,beta-lactamase_2500,P62593,0.319554,NO,100,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.218,-3.935,2.717,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.361275,0.00413885,0.319554 beta-lactamase_2500_T131W,beta-lactamase_2500_131,TEM-1,beta-lactamase_2500,P62593,0.319588,NO,131,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.328,-5.315,3.987,,,H,A,0.22,-0.69,3.048,,67.48,PPH,-1.00867,0.361275,0.00345886,0.319588 beta-lactamase_L247S,beta-lactamase_247,TEM-1,beta-lactamase,P62593,0.319592,NO,247,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.48,-3.602,2.122,5.28771,0.007,E,B,2.89,-0.72,2.951,,63.99,HHO,-1.79833,0.221079,0.00611275,0.319592 beta-lactamase_2500_V117Q,beta-lactamase_2500_117,TEM-1,beta-lactamase_2500,P62593,0.31965,NO,117,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.53,-4.247,2.717,,,H,A,0.44,-0.34,1.23,,65.03,PHB,-1.741,0.361275,0.00467906,0.31965 beta-lactamase_156_C75K,beta-lactamase_156_75,TEM-1,beta-lactamase_156,P62593,0.319665,NO,75,C,K,CK,Special,PositiveCharge,5.07,9.74,4.67,202,121,146,25,108.5,168.6,60.1,-1.245,-3.786,2.541,,,H,A,0.46,-0.87,0.876,,50,HOO,-1.24333,0.111618,0.0034616,0.319665 kka2_1:1_G181P,kka2_1:1_181,Kka2,kka2_1:1,P00552,0.319669,NO,181,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-2.698,-3.097,0.399,,0.379,S,B,0.75,0.78,15.356,15.356,71.59,AOA,-2.21,0.520039,0.00728319,0.319669 beta-lactamase_625_N134S,beta-lactamase_625_134,TEM-1,beta-lactamase_625,P62593,0.319731,NO,134,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-0.879,-2.985,2.106,,0.138,H,A,0.61,-0.6,3.776,,53.15,HPH,-1.02233,0.213352,0.000644786,0.319731 kka2_1:1_F264H,kka2_1:1_264,Kka2,kka2_1:1,P00552,0.319786,NO,264,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.02,-4.405,3.385,,0.296,.,?,0.58,0.02,2.303,,71.59,HHNA,-0.9655,0.520039,,0.319786 kka2_1:1_C131S,kka2_1:1_131,Kka2,kka2_1:1,P00552,0.319859,NO,131,C,S,CS,Special,Polar,5.07,5.68,0.61,112,121,105,-16,108.5,89,-19.5,-0.831,-3.414,2.583,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.520039,0.00170814,0.319859 kka2_1:4_F240G,kka2_1:4_240,Kka2,kka2_1:4,P00552,0.319872,NO,240,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-0.911,-3.675,2.764,,,H,A,0.58,-1.21,5.798,,50.38,BHH,-1.67267,0.168804,0.00552543,0.319872 kka2_1:2_D183M,kka2_1:2_183,Kka2,kka2_1:2,P00552,0.319916,NO,183,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.204,-4.843,3.639,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.295029,0.00426304,0.319916 kka2_1:1_L152W,kka2_1:1_152,Kka2,kka2_1:1,P00552,0.319948,NO,152,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.521,-5.416,3.895,,0.547,.,A,0.55,1.36,1.589,,63.64,OHH,-1.162,0.520039,0.00674868,0.319948 beta-lactamase_625_A40P,beta-lactamase_625_40,TEM-1,beta-lactamase_625,P62593,0.319962,NO,40,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.402,-3.856,2.454,,0.155,S,B,0.46,0.21,1.357,,73.78,OHB,-1.40267,0.213352,0.00490026,0.319962 kka2_1:2_G95L,kka2_1:2_95,Kka2,kka2_1:2,P00552,0.319985,NO,95,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-2.403,-3.574,1.171,,0.126,E,B,0.29,-0.74,0.359,,71.59,HOA,-2.198,0.295029,0.00743616,0.319985 kka2_1:1_E169L,kka2_1:1_169,Kka2,kka2_1:1,P00552,0.32006,NO,169,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.996,-3.06,1.064,,0.422,H,A,1.04,0.3,7.546,7.546,65.53,HAH,-1.755,0.520039,0.00730086,0.32006 kka2_1:8_R258P,kka2_1:8_258,Kka2,kka2_1:8,P00552,0.320063,NO,258,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.626,-4.055,2.429,,0.316,H,A,0.16,-0.85,5.58,,53.03,HBH,-1.25933,0.100394,0.00983174,0.320063 kka2_1:8_R258P,kka2_1:8_258,Kka2,kka2_1:8,P00552,0.320063,NO,258,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.626,-4.055,2.429,,0.316,H,A,0.16,-0.85,5.58,,53.03,HBH,-1.25933,0.100394,0.00983174,0.320063 E1_Ubiquitin_G75S,E1_Ubiquitin_75,Uba1,E1_Ubiquitin,P0CG63,0.320071,NO,75,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.999,-3.081,2.082,,0.552,T,A,0.75,0.9,4.369,,83.73,BOO,-1.1,0.18783,0.00153276,0.320071 E1_Ubiquitin_I44D,E1_Ubiquitin_44,Uba1,E1_Ubiquitin,P0CG63,0.320071,NO,44,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.432,-3.726,2.294,,,E,B,0.27,-1.17,4.57,,78.74,HHH,-1.25633,0.18783,0.00209731,0.320071 beta-lactamase_156_L73K,beta-lactamase_156_73,TEM-1,beta-lactamase_156,P62593,0.320155,NO,73,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.507,-3.846,2.339,,,H,A,0.55,-0.64,2.09,,67.83,HHH,-1.487,0.111618,0.00488983,0.320155 kka2_1:1_L259W,kka2_1:1_259,Kka2,kka2_1:1,P00552,0.320211,NO,259,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.088,-5.209,4.121,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.520039,0.0206964,0.320211 PSD95pdz3_V328N,PSD95pdz3_328,PSD95pdz3,PSD95pdz3,P31016,0.320245,NO,328,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.465,-3.805,2.34,5.28275,,,,,16.8775,,,,HHO,-1.36767,0.0758425,0.000986706,0.320245 kka2_1:1_A215D,kka2_1:1_215,Kka2,kka2_1:1,P00552,0.320295,NO,215,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.968,-3.663,2.695,,0.039,E,B,0.46,-0.59,0.754,,50.38,HHA,-1.00467,0.520039,0.00529129,0.320295 beta-lactamase_2500_L197E,beta-lactamase_2500_197,TEM-1,beta-lactamase_2500,P62593,0.320318,NO,197,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.853,-3.853,3,,0.007,S,B,0.55,0.33,2.421,,60.14,HHP,-1.833,0.361275,0.00144602,0.320318 beta-lactamase_156_I229R,beta-lactamase_156_229,TEM-1,beta-lactamase_156,P62593,0.320342,NO,229,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.267,-4.174,2.907,,0.083,E,B,0.48,-0.76,1.114,,50,HHH,-1.58767,0.111618,0.00477249,0.320342 beta-lactamase_2500_M115C,beta-lactamase_2500_115,TEM-1,beta-lactamase_2500,P62593,0.320386,NO,115,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.389,-4.767,3.378,,0.019,E,B,0.55,0.08,3.261,,69.58,OHP,-1.25433,0.361275,0.0034337,0.320386 beta-lactamase_625_I277D,beta-lactamase_625_277,TEM-1,beta-lactamase_625,P62593,0.320439,NO,277,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.213352,0.0169305,0.320439 kka2_1:2_Y22G,kka2_1:2_22,Kka2,kka2_1:2,P00552,0.320464,NO,22,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-1.583,-2.411,0.828,,0.122,.,B,0.21,-0.8,1.838,,65.53,OHA,-1.80333,0.295029,0.00598977,0.320464 beta-lactamase_625_R162W,beta-lactamase_625_162,TEM-1,beta-lactamase_625,P62593,0.320495,NO,162,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.016,-5.367,4.351,,0.124,S,B,1.2,-0.37,1.445,,64.69,ABH,-1.25,0.213352,0.000561334,0.320495 beta-lactamase_2500_T69P,beta-lactamase_2500_69,TEM-1,beta-lactamase_2500,P62593,0.320507,NO,69,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-0.973,-3.715,2.742,,,G,A,0.22,-1.24,2.05,,93.01,PPH,-1.01833,0.361275,0.00127498,0.320507 kka2_1:1_T51H,kka2_1:1_51,Kka2,kka2_1:1,P00552,0.320527,NO,51,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.199,-2.994,0.795,,0.05,E,B,0.22,-0.05,3.056,,63.64,BPA,-1.76767,0.520039,0.00628861,0.320527 kka2_1:1_L57K,kka2_1:1_57,Kka2,kka2_1:1,P00552,0.320577,NO,57,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.898,-3.894,1.996,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.520039,0.00723769,0.320577 kka2_1:1_R44A,kka2_1:1_44,Kka2,kka2_1:1,P00552,0.320661,NO,44,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.062,-2.384,0.322,,0.487,S,B,1.2,-0.35,2.717,,71.59,OBO,-1.80767,0.520039,0.00745043,0.320661 beta-lactamase_2500_G281W,beta-lactamase_2500_281,TEM-1,beta-lactamase_2500,P62593,0.320778,NO,281,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.361275,0.0406482,0.320778 beta-lactamase_2500_T27D,beta-lactamase_2500_27,TEM-1,beta-lactamase_2500,P62593,0.320819,NO,27,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.905,-3.5,1.595,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.361275,0.00306559,0.320819 kka2_1:1_V84I,kka2_1:1_84,Kka2,kka2_1:1,P00552,0.320828,NO,84,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-2.279,-2.844,0.565,,0.258,E,B,0.44,1.03,3.484,,71.59,HHP,-2.337,0.520039,0.00724019,0.320828 beta-lactamase_625_G240E,beta-lactamase_625_240,TEM-1,beta-lactamase_625,P62593,0.320862,NO,240,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.213352,0.00591201,0.320862 kka2_1:4_V97N,kka2_1:4_97,Kka2,kka2_1:4,P00552,0.320913,NO,97,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.453,-4.261,2.808,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.168804,0.00737869,0.320913 kka2_1:2_L102C,kka2_1:2_102,Kka2,kka2_1:2,P00552,0.320969,NO,102,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.804,-4.689,3.885,,,T,A,1.59,-1.17,4.258,,42.42,AHH,-1.398,0.295029,0.00201332,0.320969 beta-lactamase_625_A132V,beta-lactamase_625_132,TEM-1,beta-lactamase_625,P62593,0.320999,NO,132,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.9,-2.46,1.56,,,H,A,0.46,-0.93,0.316,,64.69,PHH,-1.138,0.213352,0.000962524,0.320999 beta-lactamase_156_G234F,beta-lactamase_156_234,TEM-1,beta-lactamase_156,P62593,0.321065,NO,234,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.62,-4.292,3.672,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.111618,0.000889577,0.321065 kka2_1:1_A78V,kka2_1:1_78,Kka2,kka2_1:1,P00552,0.321102,NO,78,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.744,-3.452,1.708,,0.078,.,B,0.46,-0.53,0.206,,56.06,OHH,-1.863,0.520039,0.00457299,0.321102 kka2_1:8_L260G,kka2_1:8_260,Kka2,kka2_1:8,P00552,0.321104,NO,260,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.741,-3.836,3.095,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.100394,0.0233782,0.321104 kka2_1:8_L260G,kka2_1:8_260,Kka2,kka2_1:8,P00552,0.321104,NO,260,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.741,-3.836,3.095,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.100394,0.0233782,0.321104 kka2_1:1_K138I,kka2_1:1_138,Kka2,kka2_1:1,P00552,0.321164,NO,138,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-2.5,-3.288,0.788,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.520039,0.00628542,0.321164 kka2_1:2_G30W,kka2_1:2_30,Kka2,kka2_1:2,P00552,0.321185,NO,30,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.596,-5.126,4.53,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.295029,0.00159208,0.321185 kka2_1:1_D250M,kka2_1:1_250,Kka2,kka2_1:1,P00552,0.321208,NO,250,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.015,-4.907,3.892,,0.274,.,b,0.75,-0.46,4.177,,51.89,OAP,-1.83933,0.520039,0.0177103,0.321208 kka2_1:2_D190V,kka2_1:2_190,Kka2,kka2_1:2,P00552,0.321276,NO,190,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.708,-3.782,3.074,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.295029,0.00247989,0.321276 kka2_1:1_L60H,kka2_1:1_60,Kka2,kka2_1:1,P00552,0.32131,NO,60,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.997,-4.966,3.969,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.520039,0.00262176,0.32131 beta-lactamase_2500_W208E,beta-lactamase_2500_208,TEM-1,beta-lactamase_2500,P62593,0.32132,NO,208,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-0.818,-3.89,3.072,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.361275,0.00126609,0.32132 beta-lactamase_0_K254F,beta-lactamase_0_254,TEM-1,beta-lactamase_0,P62593,0.321324,NO,254,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.0500837,0.00369,0.321324 kka2_1:4_V36N,kka2_1:4_36,Kka2,kka2_1:4,P00552,0.32133,NO,36,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-0.898,-4.196,3.298,,0.292,E,B,0.44,0.21,0.278,,52.27,HHH,-1.484,0.168804,0.00245633,0.32133 beta-lactamase_R189P,beta-lactamase_189,TEM-1,beta-lactamase,P62593,0.321365,NO,189,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.844,-3.964,2.12,5.74877,0.278,H,A,0.68,1.01,1.512,,72.73,HBB,-1.668,0.221079,0.0050699,0.321365 kka2_1:4_Y22R,kka2_1:4_22,Kka2,kka2_1:4,P00552,0.321366,NO,22,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-1.583,-3.13,1.547,,0.122,.,B,0.21,-0.8,1.838,,65.53,OHA,-1.80333,0.168804,0.00598977,0.321366 beta-lactamase_2500_S80P,beta-lactamase_2500_80,TEM-1,beta-lactamase_2500,P62593,0.32137,NO,80,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.029,-3.939,1.91,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.361275,0.00565569,0.32137 beta-lactamase_2500_I206D,beta-lactamase_2500_206,TEM-1,beta-lactamase_2500,P62593,0.321387,NO,206,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-2.429,-3.794,1.365,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.361275,0.00528934,0.321387 kka2_1:4_L39H,kka2_1:4_39,Kka2,kka2_1:4,P00552,0.321443,NO,39,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.223,-4.999,3.776,,,E,B,0.55,-1.21,1.998,,71.59,BHP,-1.69167,0.168804,0.00493618,0.321443 beta-lactamase_2500_D231Y,beta-lactamase_2500_231,TEM-1,beta-lactamase_2500,P62593,0.32152,NO,231,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.816,-4.385,3.569,,,E,B,0.75,-1.06,0.319,,65.38,HAB,-0.994,0.361275,0.00107395,0.32152 kka2_1:1_A248G,kka2_1:1_248,Kka2,kka2_1:1,P00552,0.321538,NO,248,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.124,-2.636,0.512,,0.825,S,b,0.46,0.46,24.72,24.72,92.05,HHO,-2.15,0.520039,0.0125484,0.321538 kka2_1:1_G164Y,kka2_1:1_164,Kka2,kka2_1:1,P00552,0.32158,NO,164,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.869,-4.442,3.573,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.520039,0.00442091,0.32158 kka2_1:4_L19K,kka2_1:4_19,Kka2,kka2_1:4,P00552,0.321655,NO,19,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.254,-3.899,2.645,,0.08,T,A,1.59,-0.26,2.645,,65.53,BHH,-2.221,0.168804,0.00620703,0.321655 kka2_1:4_F240Y,kka2_1:4_240,Kka2,kka2_1:4,P00552,0.321684,NO,240,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-0.911,-3.189,2.278,,,H,A,0.58,-1.21,5.798,,50.38,BHH,-1.67267,0.168804,0.00552543,0.321684 kka2_1:1_A56F,kka2_1:1_56,Kka2,kka2_1:1,P00552,0.321711,NO,56,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.083,-4.441,2.358,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.520039,0.00717715,0.321711 beta-lactamase_2500_V101W,beta-lactamase_2500_101,TEM-1,beta-lactamase_2500,P62593,0.321821,NO,101,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.295,-5.385,4.09,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.361275,0.00374492,0.321821 E1_Ubiquitin_G76H,E1_Ubiquitin_76,Uba1,E1_Ubiquitin,P0CG63,0.321839,NO,76,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.999,-4.55,3.551,,0.23,,B,0.75,0.08,1.702,,83.73,OOO,-0.999,0.18783,0.00125575,0.321839 kka2_1:2_S32N,kka2_1:2_32,Kka2,kka2_1:2,P00552,0.321867,NO,32,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-0.804,-3.251,2.447,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.295029,0.00149998,0.321867 beta-lactamase_156_N130Y,beta-lactamase_156_130,TEM-1,beta-lactamase_156,P62593,0.321872,NO,130,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-0.798,-4.162,3.364,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.111618,0.000683376,0.321872 beta-lactamase_625_G76D,beta-lactamase_625_76,TEM-1,beta-lactamase_625,P62593,0.321926,NO,76,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.189,-3.614,2.425,,,H,A,0.29,-0.67,3.059,,67.83,OOH,-1.22267,0.213352,0.00476637,0.321926 kka2_1:1_C192P,kka2_1:1_192,Kka2,kka2_1:1,P00552,0.321974,NO,192,C,P,CP,Special,Special,5.07,6.3,1.23,169,121,115,-6,108.5,112.7,4.2,-1.067,-4.099,3.032,,0.095,.,B,0.46,-0.75,2.749,,50,HOH,-0.960333,0.520039,0.00485428,0.321974 beta-lactamase_625_A34R,beta-lactamase_625_34,TEM-1,beta-lactamase_625,P62593,0.322037,NO,34,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.059,-4.061,2.002,,,H,A,0.46,-0.54,3.614,,73.78,AHA,-1.74967,0.213352,0.00407913,0.322037 kka2_1:8_V97K,kka2_1:8_97,Kka2,kka2_1:8,P00552,0.322149,NO,97,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.453,-3.837,2.384,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.100394,0.00737869,0.322149 kka2_1:8_V97K,kka2_1:8_97,Kka2,kka2_1:8,P00552,0.322149,NO,97,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.453,-3.837,2.384,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.100394,0.00737869,0.322149 kka2_1:1_F264N,kka2_1:1_264,Kka2,kka2_1:1,P00552,0.322155,NO,264,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.02,-4.176,3.156,,0.296,.,?,0.58,0.02,2.303,,71.59,HHNA,-0.9655,0.520039,,0.322155 kka2_1:1_Q252V,kka2_1:1_252,Kka2,kka2_1:1,P00552,0.32216,NO,252,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.63,-3.102,0.472,,0.906,H,A,0.64,0.35,1.369,,92.05,PPB,-2.20733,0.520039,0.0121001,0.32216 beta-lactamase_625_P65F,beta-lactamase_625_65,TEM-1,beta-lactamase_625,P62593,0.3222,NO,65,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.894,-4.306,3.412,,0.098,E,B,0.52,-0.62,0.3,,40.56,HOH,-1.03233,0.213352,0.00152776,0.3222 kka2_1:1_W91E,kka2_1:1_91,Kka2,kka2_1:1,P00552,0.322238,NO,91,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-1.178,-3.842,2.664,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.520039,0.00358653,0.322238 beta-lactamase_625_Y103K,beta-lactamase_625_103,TEM-1,beta-lactamase_625,P62593,0.322267,NO,103,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-1.33,-3.666,2.336,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.213352,0.00443048,0.322267 kka2_1:8_L241Y,kka2_1:8_241,Kka2,kka2_1:8,P00552,0.322271,NO,241,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.158,-3.64,2.482,,0.08,H,A,1.59,-0.82,1.136,,63.26,HHH,-1.58533,0.100394,0.0117299,0.322271 kka2_1:8_L241Y,kka2_1:8_241,Kka2,kka2_1:8,P00552,0.322271,NO,241,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.158,-3.64,2.482,,0.08,H,A,1.59,-0.82,1.136,,63.26,HHH,-1.58533,0.100394,0.0117299,0.322271 beta-lactamase_0_L120Y,beta-lactamase_0_120,TEM-1,beta-lactamase_0,P62593,0.322277,NO,120,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.044,-3.856,2.812,,,H,A,0.55,-1.13,1.2,,64.69,AHO,-1.13633,0.0500837,0.00143563,0.322277 kka2_1:1_L57W,kka2_1:1_57,Kka2,kka2_1:1,P00552,0.322305,NO,57,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.898,-3.389,1.491,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.520039,0.00723769,0.322305 beta-lactamase_625_A124W,beta-lactamase_625_124,TEM-1,beta-lactamase_625,P62593,0.322342,NO,124,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.181,-5.322,4.141,,,H,A,0.46,-0.9,2.027,,64.34,HHH,-1.152,0.213352,0.00481399,0.322342 beta-lactamase_0_S68I,beta-lactamase_0_68,TEM-1,beta-lactamase_0,P62593,0.322353,NO,68,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-0.913,-3.834,2.921,,0.064,G,A,0.27,-1.03,1.441,,64.69,HPP,-1.37233,0.0500837,0.000800065,0.322353 kka2_1:4_E262T,kka2_1:4_262,Kka2,kka2_1:4,P00552,0.322362,NO,262,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-0.829,-3.473,2.644,,0.059,G,A,1.04,-0.18,2.383,,42.42,AAH,-0.816,0.168804,0.0191586,0.322362 kka2_1:1_Q100D,kka2_1:1_100,Kka2,kka2_1:1,P00552,0.322387,NO,100,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.77,-3.173,0.403,,0.646,E,B,0.4,-0.79,15.116,15.116,71.59,OPA,-1.46467,0.520039,0.0066405,0.322387 beta-lactamase_Y260Q,beta-lactamase_260,TEM-1,beta-lactamase,P62593,0.322399,NO,260,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-1.101,-4.075,2.974,5.50878,,E,B,0.73,-1.04,0.865,,60.49,HHP,-1.83433,0.221079,0.00471757,0.322399 kka2_1:8_D190N,kka2_1:8_190,Kka2,kka2_1:8,P00552,0.322401,NO,190,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.708,-3.251,2.543,,0.213,S,b,0.29,-0.82,,,,OAH,-0.711667,0.100394,0.00247989,0.322401 kka2_1:8_D190N,kka2_1:8_190,Kka2,kka2_1:8,P00552,0.322401,NO,190,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.708,-3.251,2.543,,0.213,S,b,0.29,-0.82,,,,OAH,-0.711667,0.100394,0.00247989,0.322401 kka2_1:4_G95Y,kka2_1:4_95,Kka2,kka2_1:4,P00552,0.32244,NO,95,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-2.403,-4.397,1.994,,0.126,E,B,0.29,-0.74,0.359,,71.59,HOA,-2.198,0.168804,0.00743616,0.32244 beta-lactamase_D207P,beta-lactamase_207,TEM-1,beta-lactamase,P62593,0.32246,NO,207,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.064,-3.955,1.891,5.40404,0.409,H,A,0.23,0.12,1.975,,77.62,HAH,-1.77033,0.221079,0.00592942,0.32246 beta-lactamase_156_T179H,beta-lactamase_156_179,TEM-1,beta-lactamase_156,P62593,0.322513,NO,179,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.085,-2.971,1.886,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.111618,0.00226045,0.322513 kka2_1:1_L193Q,kka2_1:1_193,Kka2,kka2_1:1,P00552,0.322514,NO,193,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.983,-2.972,1.989,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.520039,0.00480179,0.322514 kka2_1:1_I207G,kka2_1:1_207,Kka2,kka2_1:1,P00552,0.322588,NO,207,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.175,-3.853,2.678,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.520039,0.00611824,0.322588 kka2_1:1_C209K,kka2_1:1_209,Kka2,kka2_1:1,P00552,0.322597,NO,209,C,K,CK,Special,PositiveCharge,5.07,9.74,4.67,202,121,146,25,108.5,168.6,60.1,-0.906,-3.933,3.027,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.520039,0.00260862,0.322597 beta-lactamase_156_I285D,beta-lactamase_156_285,TEM-1,beta-lactamase_156,P62593,0.322623,NO,285,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.111618,0.101555,0.322623 beta-lactamase_T27W,beta-lactamase_27,TEM-1,beta-lactamase,P62593,0.322757,NO,27,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.905,-5.314,3.409,5.39752,0.007,H,A,0.69,-0.37,0.745,,93.01,APH,-1.97933,0.221079,0.00306559,0.322757 beta-lactamase_2500_E35V,beta-lactamase_2500_35,TEM-1,beta-lactamase_2500,P62593,0.322767,NO,35,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-0.869,-3.578,2.709,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.361275,0.00174441,0.322767 Pab1_F149P,Pab1_149,Pab1,Pab1,P04147,0.322793,NO,149,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.149,-4.147,2.998,,0.183,T,A,1.33,1.09,,,,HHO,-1.27767,0.175299,0.000325688,0.322793 Pab1_L133K,Pab1_133,Pab1,Pab1,P04147,0.322793,NO,133,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.039,-3.499,2.46,,0.015,,B,1.75,1.03,,,,PHB,-1.22,0.175299,0.000345939,0.322793 beta-lactamase_2500_T147P,beta-lactamase_2500_147,TEM-1,beta-lactamase_2500,P62593,0.322823,NO,147,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.149,-3.818,2.669,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.361275,0.00226017,0.322823 Pab1_V171E,Pab1_171,Pab1,Pab1,P04147,0.322842,NO,171,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.113,-3.482,2.369,,0.008,E,b,0.23,-0.34,,,,HHB,-1.19733,0.175299,0.000298662,0.322842 PSD95pdz3_I341P,PSD95pdz3_341,PSD95pdz3,PSD95pdz3,P31016,0.322862,NO,341,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.63,-3.786,2.156,5.73946,,,,,10.3187,,,,HHH,-1.50033,0.0758425,0.000824087,0.322862 beta-lactamase_W227T,beta-lactamase_227,TEM-1,beta-lactamase,P62593,0.322889,NO,227,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-0.982,-3.696,2.714,4.86393,0.272,,B,0.99,-0.29,1.37,,74.48,OHH,-1.595,0.221079,0.00226019,0.322889 kka2_1:8_M148P,kka2_1:8_148,Kka2,kka2_1:8,P00552,0.322918,NO,148,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.847,-4.116,2.269,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.100394,0.00982664,0.322918 kka2_1:8_M148P,kka2_1:8_148,Kka2,kka2_1:8,P00552,0.322918,NO,148,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.847,-4.116,2.269,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.100394,0.00982664,0.322918 kka2_1:1_Y244S,kka2_1:1_244,Kka2,kka2_1:1,P00552,0.322979,NO,244,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-0.775,-3.639,2.864,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.520039,0.00453187,0.322979 beta-lactamase_625_D83P,beta-lactamase_625_83,TEM-1,beta-lactamase_625,P62593,0.322999,NO,83,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.066,-3.748,2.682,,0.354,H,A,0.75,0.22,0.239,,48.95,HAH,-1.34733,0.213352,0.00205968,0.322999 kka2_1:1_G99L,kka2_1:1_99,Kka2,kka2_1:1,P00552,0.323054,NO,99,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.596,-3.836,3.24,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.520039,0.00186055,0.323054 beta-lactamase_156_L120W,beta-lactamase_156_120,TEM-1,beta-lactamase_156,P62593,0.323064,NO,120,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.044,-5.142,4.098,,,H,A,0.55,-1.13,7.813,,64.69,AHO,-1.13633,0.111618,0.00143563,0.323064 beta-lactamase_156_C121E,beta-lactamase_156_121,TEM-1,beta-lactamase_156,P62593,0.323123,NO,121,C,E,CE,Special,negativeCharge,5.07,3.22,-1.85,170,121,147,26,108.5,138.4,29.9,-0.953,-3.987,3.034,,,H,A,0.46,-0.81,1.136,,63.29,HOP,-1.46767,0.111618,0.000744322,0.323123 kka2_1:8_I115W,kka2_1:8_115,Kka2,kka2_1:8,P00552,0.323176,NO,115,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.606,-5.354,3.748,,0.105,H,A,1.52,-1.18,4.064,,65.53,PHH,-2.205,0.100394,0.00836567,0.323176 kka2_1:8_I115W,kka2_1:8_115,Kka2,kka2_1:8,P00552,0.323176,NO,115,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.606,-5.354,3.748,,0.105,H,A,1.52,-1.18,4.064,,65.53,PHH,-2.205,0.100394,0.00836567,0.323176 kka2_1:1_R253D,kka2_1:1_253,Kka2,kka2_1:1,P00552,0.32323,NO,253,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.356,-3.762,2.406,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.520039,0.0144195,0.32323 PSD95pdz3_H372T,PSD95pdz3_372,PSD95pdz3,PSD95pdz3,P31016,0.323236,NO,372,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-1.627,-3.328,1.701,5.5607,,,,,17.008,,,,PBA,-1.63033,0.0758425,0.00040301,0.323236 kka2_1:1_R202F,kka2_1:1_202,Kka2,kka2_1:1,P00552,0.323239,NO,202,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.761,-4.435,2.674,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.520039,0.00696498,0.323239 kka2_1:4_L47E,kka2_1:4_47,Kka2,kka2_1:4,P00552,0.323261,NO,47,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.265,-3.747,2.482,,0.139,E,B,0.55,-0.86,2.369,,63.26,HHH,-1.77933,0.168804,0.00509386,0.323261 kka2_1:4_G233K,kka2_1:4_233,Kka2,kka2_1:4,P00552,0.323281,NO,233,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.748,-3.71,2.962,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.168804,0.00232366,0.323281 beta-lactamase_2500_H151P,beta-lactamase_2500_151,TEM-1,beta-lactamase_2500,P62593,0.323289,NO,151,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-2.96,-3.911,0.951,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.361275,0.00216946,0.323289 kka2_1:8_F240P,kka2_1:8_240,Kka2,kka2_1:8,P00552,0.323305,NO,240,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-0.911,-4.356,3.445,,,H,A,1.62,-1.21,0.697,,50.38,BHH,-1.67267,0.100394,0.00552543,0.323305 kka2_1:8_F240P,kka2_1:8_240,Kka2,kka2_1:8,P00552,0.323305,NO,240,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-0.911,-4.356,3.445,,,H,A,1.62,-1.21,0.697,,50.38,BHH,-1.67267,0.100394,0.00552543,0.323305 kka2_1:1_F171Y,kka2_1:1_171,Kka2,kka2_1:1,P00552,0.323308,NO,171,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.326,-2.217,0.891,,0.154,H,A,1.62,-0.1,13.679,13.679,63.64,HHH,-1.45433,0.520039,0.00821426,0.323308 kka2_1:4_L193K,kka2_1:4_193,Kka2,kka2_1:4,P00552,0.323333,NO,193,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.983,-3.668,2.685,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.168804,0.00480179,0.323333 PSD95pdz3_L379K,PSD95pdz3_379,PSD95pdz3,PSD95pdz3,P31016,0.323361,NO,379,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.347,-3.364,2.017,5.37777,,,,,16.8762,,,,HHB,-1.35667,0.0758425,0.00029733,0.323361 kka2_1:1_G151E,kka2_1:1_151,Kka2,kka2_1:1,P00552,0.3234,NO,151,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.873,-3.557,2.684,,0.678,T,l,0.29,1.36,0.226,,49.62,HOH,-1.11433,0.520039,0.00339918,0.3234 kka2_1:8_L102H,kka2_1:8_102,Kka2,kka2_1:8,P00552,0.323434,NO,102,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.804,-4.931,4.127,,,T,A,1.59,-1.17,0.97,,42.42,AHH,-1.398,0.100394,0.00201332,0.323434 kka2_1:8_L102H,kka2_1:8_102,Kka2,kka2_1:8,P00552,0.323434,NO,102,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.804,-4.931,4.127,,,T,A,1.59,-1.17,0.97,,42.42,AHH,-1.398,0.100394,0.00201332,0.323434 beta-lactamase_0_Y95K,beta-lactamase_0_95,TEM-1,beta-lactamase_0,P62593,0.323459,NO,95,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-1.715,-3.936,2.221,,0.122,,b,0.21,-0.37,2.914,,77.62,BHP,-2.16167,0.0500837,0.00479449,0.323459 kka2_1:4_D220F,kka2_1:4_220,Kka2,kka2_1:4,P00552,0.323529,NO,220,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.787,-4.288,3.501,,,H,A,0.75,-1.14,1.237,,46.59,PAH,-1.152,0.168804,0.00158066,0.323529 beta-lactamase_2500_M67D,beta-lactamase_2500_67,TEM-1,beta-lactamase_2500,P62593,0.323551,NO,67,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-2.231,-3.779,1.548,,0.006,G,P,0.55,-0.81,2.653,,65.03,HHP,-1.502,0.361275,0.00409753,0.323551 kka2_1:1_W236K,kka2_1:1_236,Kka2,kka2_1:1,P00552,0.323554,NO,236,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-1.363,-3.959,2.596,,0.303,H,A,1.51,-0.76,12.263,12.263,48.48,AHH,-1.81267,0.520039,0.0088796,0.323554 kka2_1:1_D183Q,kka2_1:1_183,Kka2,kka2_1:1,P00552,0.323555,NO,183,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.204,-2.915,1.711,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.520039,0.00426304,0.323555 kka2_1:4_L102Q,kka2_1:4_102,Kka2,kka2_1:4,P00552,0.323593,NO,102,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.804,-4.12,3.316,,,T,A,0.55,-1.17,0.65,,42.42,AHH,-1.398,0.168804,0.00201332,0.323593 kka2_1:2_W24Y,kka2_1:2_24,Kka2,kka2_1:2,P00552,0.323604,NO,24,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-1.779,-3.045,1.266,,0.477,E,B,1.51,-0.21,2.666,,56.06,AHH,-2.24467,0.295029,0.00631564,0.323604 beta-lactamase_2500_T131M,beta-lactamase_2500_131,TEM-1,beta-lactamase_2500,P62593,0.323653,NO,131,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.328,-4.602,3.274,,,H,A,0.22,-0.69,3.048,,67.48,PPH,-1.00867,0.361275,0.00345886,0.323653 beta-lactamase_156_R242P,beta-lactamase_156_242,TEM-1,beta-lactamase_156,P62593,0.32366,NO,242,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.111618,0.00452879,0.32366 beta-lactamase_625_K232F,beta-lactamase_625_232,TEM-1,beta-lactamase_625,P62593,0.323671,NO,232,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.012,-4.334,3.322,,,E,B,2.34,-1.1,1.992,,65.03,ABP,-1.238,0.213352,0.00313441,0.323671 kka2_1:2_K112S,kka2_1:2_112,Kka2,kka2_1:2,P00552,0.323792,NO,112,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-2.491,-2.816,0.325,,0.076,H,A,2.34,-1.37,23.433,23.433,56.06,ABH,-2.00133,0.295029,0.00645389,0.323792 beta-lactamase_F13R,beta-lactamase_13,TEM-1,beta-lactamase,P62593,0.323831,NO,13,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-2.394,-3.911,1.517,,,,,,,4.079,,77.62,OHH,-2.382,0.221079,0.0029078,0.323831 kka2_1:1_V185C,kka2_1:1_185,Kka2,kka2_1:1,P00552,0.32385,NO,185,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.045,-3.114,2.069,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.520039,0.00367031,0.32385 Pab1_V171N,Pab1_171,Pab1,Pab1,P04147,0.323861,NO,171,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.113,-3.94,2.827,,0.008,E,b,0.23,-0.34,,,,HHB,-1.19733,0.175299,0.000298662,0.323861 kka2_1:1_L94Y,kka2_1:1_94,Kka2,kka2_1:1,P00552,0.323883,NO,94,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.618,-4.101,2.483,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.520039,0.00520888,0.323883 kka2_1:1_V49E,kka2_1:1_49,Kka2,kka2_1:1,P00552,0.323919,NO,49,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.614,-3.892,2.278,,,E,B,0.44,-0.77,3.665,3.665,64.39,HHB,-1.3,0.520039,0.00615685,0.323919 beta-lactamase_39_G249L,beta-lactamase_39_249,TEM-1,beta-lactamase_39,P62593,0.323939,NO,249,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.312,,,,0.256,S,B,0.23,0.04,30.841,30.841,72.73,HOO,-1.81367,0.0495842,0.00220169,0.323939 kka2_1:2_E169F,kka2_1:2_169,Kka2,kka2_1:2,P00552,0.323978,NO,169,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.996,-3.429,1.433,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.295029,0.00730086,0.323978 kka2_1:1_R140C,kka2_1:1_140,Kka2,kka2_1:1,P00552,0.324029,NO,140,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.351,-5.118,3.767,,0.12,H,A,1.2,0.2,11.345,11.345,53.03,BBH,-1.885,0.520039,0.00430167,0.324029 kka2_1:1_F263E,kka2_1:1_263,Kka2,kka2_1:1,P00552,0.324047,NO,263,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-0.911,-3.952,3.041,,0.006,G,A,0.58,-0.12,2.284,,45.83,AHH,-0.92,0.520039,0.0172454,0.324047 kka2_1:2_F171I,kka2_1:2_171,Kka2,kka2_1:2,P00552,0.324056,NO,171,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.326,-2.784,1.458,,0.154,H,A,0.58,-0.1,2.645,,63.64,HHH,-1.45433,0.295029,0.00821426,0.324056 beta-lactamase_2500_V117C,beta-lactamase_2500_117,TEM-1,beta-lactamase_2500,P62593,0.324125,NO,117,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.53,-4.787,3.257,,,H,A,0.44,-0.34,1.23,,65.03,PHB,-1.741,0.361275,0.00467906,0.324125 kka2_1:1_D154I,kka2_1:1_154,Kka2,kka2_1:1,P00552,0.324129,NO,154,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.876,-4.094,3.218,,0.457,.,b,0.75,1.48,0.658,,52.65,HAP,-1.52467,0.520039,0.00292633,0.324129 kka2_1:1_G55E,kka2_1:1_55,Kka2,kka2_1:1,P00552,0.324129,NO,55,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.625,-2.785,1.16,,0.517,S,b,0.29,1.19,4.035,,63.64,POH,-2.05967,0.520039,0.00667877,0.324129 beta-lactamase_625_W288V,beta-lactamase_625_288,TEM-1,beta-lactamase_625,P62593,0.324138,NO,288,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,,,,,,,,,,,,,BHO,,0.213352,,0.324138 kka2_1:2_A108Y,kka2_1:2_108,Kka2,kka2_1:2,P00552,0.324151,NO,108,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.061,-4.432,2.371,,0.243,.,B,0.46,-1.34,2.462,,71.59,HHO,-1.57033,0.295029,0.00751209,0.324151 gb1_N261Y,gb1_261,gb1,gb1,P06654,0.32422,NO,261,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-1.863,-4.051,2.188,,,,,,,1.191,,44.87,HPA,-2.16033,0.177985,0.0061875,0.32422 gb1_V265R,gb1_265,gb1,gb1,P06654,0.32422,NO,265,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.843,-3.811,1.968,,,,,,,0.402,,11.83,OHA,-1.64567,0.177985,0.00360613,0.32422 beta-lactamase_625_E164D,beta-lactamase_625_164,TEM-1,beta-lactamase_625,P62593,0.324248,NO,164,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-0.948,-2.949,2.001,,0.011,T,B,1.04,-0.4,1.321,,64.69,HAO,-1.388,0.213352,0.00137286,0.324248 beta-lactamase_E119W,beta-lactamase_119,TEM-1,beta-lactamase,P62593,0.324261,NO,119,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.412,-5.452,4.04,5.33349,0.358,H,A,1.52,0.51,1.983,,63.99,BAH,-1.623,0.221079,0.00386966,0.324261 kka2_1:1_K50N,kka2_1:1_50,Kka2,kka2_1:1,P00552,0.324293,NO,50,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-0.833,-3.499,2.666,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.520039,0.00138626,0.324293 kka2_1:1_D52W,kka2_1:1_52,Kka2,kka2_1:1,P00552,0.324363,NO,52,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.271,-5.394,3.123,,0.22,E,B,0.75,0.8,2.64,,71.59,PAH,-2.38367,0.520039,0.00175694,0.324363 beta-lactamase_625_L218W,beta-lactamase_625_218,TEM-1,beta-lactamase_625,P62593,0.324451,NO,218,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.391,-5.26,3.869,,,I,b,0.55,-0.53,17.202,17.202,74.48,OHH,-1.58867,0.213352,0.00618274,0.324451 beta-lactamase_2500_E46W,beta-lactamase_2500_46,TEM-1,beta-lactamase_2500,P62593,0.324484,NO,46,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.94,-5.418,3.478,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.361275,0.00427568,0.324484 beta-lactamase_625_V78K,beta-lactamase_625_78,TEM-1,beta-lactamase_625,P62593,0.324496,NO,78,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.459,-3.849,2.39,,,H,A,0.44,-0.47,2.045,,63.64,HHH,-1.17833,0.213352,0.00492501,0.324496 kka2_1:1_S204W,kka2_1:1_204,Kka2,kka2_1:1,P00552,0.324517,NO,204,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.353,-5.392,4.039,,0.144,E,A,0.27,-1.2,3.022,,65.53,HPO,-0.953333,0.520039,0.00881794,0.324517 kka2_1:2_G55P,kka2_1:2_55,Kka2,kka2_1:2,P00552,0.324521,NO,55,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.625,-4.068,2.443,,0.517,S,b,0.75,1.19,15.753,15.753,63.64,POH,-2.05967,0.295029,0.00667877,0.324521 kka2_1:2_E262F,kka2_1:2_262,Kka2,kka2_1:2,P00552,0.324526,NO,262,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-0.829,-4.344,3.515,,0.059,G,A,1.04,-0.18,2.383,,42.42,AAH,-0.816,0.295029,0.0191586,0.324526 kka2_1:1_A137K,kka2_1:1_137,Kka2,kka2_1:1,P00552,0.324527,NO,137,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.156,-3.751,1.595,,0.029,H,A,0.46,0.34,1.323,,63.26,PHB,-2.559,0.520039,0.00515054,0.324527 beta-lactamase_2500_T131P,beta-lactamase_2500_131,TEM-1,beta-lactamase_2500,P62593,0.324643,NO,131,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.328,-3.82,2.492,,,H,A,0.22,-0.69,3.048,,67.48,PPH,-1.00867,0.361275,0.00345886,0.324643 kka2_1:2_R44F,kka2_1:2_44,Kka2,kka2_1:2,P00552,0.324734,NO,44,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.062,-4.405,2.343,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.295029,0.00745043,0.324734 kka2_1:1_P179C,kka2_1:1_179,Kka2,kka2_1:1,P00552,0.324785,NO,179,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.974,-5.011,4.037,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.520039,0.00298346,0.324785 kka2_1:1_A191D,kka2_1:1_191,Kka2,kka2_1:1,P00552,0.324799,NO,191,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.831,-3.72,2.889,,,.,b,0.46,-0.94,0.53,,50,AHO,-0.868667,0.520039,0.00338807,0.324799 beta-lactamase_39_G43L,beta-lactamase_39_43,TEM-1,beta-lactamase_39,P62593,0.324816,NO,43,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.62,-3.808,3.188,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.0495842,0.00120151,0.324816 kka2_1:4_G205I,kka2_1:4_205,Kka2,kka2_1:4,P00552,0.324922,NO,205,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.596,-4.264,3.668,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.168804,0.00221855,0.324922 kka2_1:8_D101R,kka2_1:8_101,Kka2,kka2_1:8,P00552,0.324979,NO,101,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.028,-3.968,2.94,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.100394,0.00423361,0.324979 kka2_1:8_D101R,kka2_1:8_101,Kka2,kka2_1:8,P00552,0.324979,NO,101,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.028,-3.968,2.94,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.100394,0.00423361,0.324979 kka2_1:1_L57Q,kka2_1:1_57,Kka2,kka2_1:1,P00552,0.325012,NO,57,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.898,-3.254,1.356,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.520039,0.00723769,0.325012 beta-lactamase_156_L248D,beta-lactamase_156_248,TEM-1,beta-lactamase_156,P62593,0.32504,NO,248,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.111618,0.00428493,0.32504 beta-lactamase_625_M209W,beta-lactamase_625_209,TEM-1,beta-lactamase_625,P62593,0.325062,NO,209,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.442,-4.979,3.537,,,H,A,0.55,-0.97,1.167,,64.69,HHA,-1.52633,0.213352,0.00625021,0.325062 beta-lactamase_0_S256Q,beta-lactamase_0_256,TEM-1,beta-lactamase_0,P62593,0.32507,NO,256,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.0500837,0.00710634,0.32507 kka2_1:2_P12Y,kka2_1:2_12,Kka2,kka2_1:2,P00552,0.325081,NO,12,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.853,-4.385,3.532,,,.,B,0.52,1.25,0.261,,48.11,POH,-1.80767,0.295029,0.00500011,0.325081 kka2_1:2_I115N,kka2_1:2_115,Kka2,kka2_1:2,P00552,0.325108,NO,115,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.606,-4.227,2.621,,0.105,H,A,0.48,-1.18,0.878,,65.53,PHH,-2.205,0.295029,0.00836567,0.325108 kka2_1:1_V49W,kka2_1:1_49,Kka2,kka2_1:1,P00552,0.325111,NO,49,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.614,-5.38,3.766,,,E,B,0.44,-0.77,3.665,3.665,64.39,HHB,-1.3,0.520039,0.00615685,0.325111 kka2_1:1_C192W,kka2_1:1_192,Kka2,kka2_1:1,P00552,0.325147,NO,192,C,W,CW,Special,Hydrophobic,5.07,5.89,0.82,215,121,204,83,108.5,227.8,119.3,-1.067,-5.111,4.044,,0.095,.,B,0.46,-0.75,2.749,,50,HOH,-0.960333,0.520039,0.00485428,0.325147 kka2_1:2_A64N,kka2_1:2_64,Kka2,kka2_1:2,P00552,0.325183,NO,64,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.496,-4.101,2.605,,0.039,H,A,0.46,-0.57,14.509,14.509,56.06,AHH,-1.334,0.295029,0.00705578,0.325183 kka2_1:1_R18Y,kka2_1:1_18,Kka2,kka2_1:1,P00552,0.325193,NO,18,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.055,-3.413,1.358,,0.474,T,A,1.2,0.54,11.422,11.422,71.59,ABH,-1.821,0.520039,0.00724065,0.325193 kka2_1:2_C192Q,kka2_1:2_192,Kka2,kka2_1:2,P00552,0.325215,NO,192,C,Q,CQ,Special,Polar,5.07,6.24429,1.17429,154,121,146,25,108.5,143.8,35.3,-1.067,-4.263,3.196,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.295029,0.00485428,0.325215 kka2_1:1_E160T,kka2_1:1_160,Kka2,kka2_1:1,P00552,0.325228,NO,160,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.683,-3.562,1.879,,0.989,G,A,1.04,2.28,0.273,,71.59,AAA,-1.36133,0.520039,0.00935762,0.325228 kka2_1:4_C192D,kka2_1:4_192,Kka2,kka2_1:4,P00552,0.325255,NO,192,C,D,CD,Special,negativeCharge,5.07,5.0516,-0.0184,154,121,133,12,108.5,111.1,2.6,-1.067,-3.871,2.804,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.168804,0.00485428,0.325255 kka2_1:1_I29H,kka2_1:1_29,Kka2,kka2_1:1,P00552,0.325348,NO,29,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.692,-4.894,3.202,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.520039,0.00619521,0.325348 E1_Ubiquitin_I44R,E1_Ubiquitin_44,Uba1,E1_Ubiquitin,P0CG63,0.325376,NO,44,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.432,-3.898,2.466,,,E,B,0.27,-1.17,4.57,,78.74,HHH,-1.25633,0.18783,0.00209731,0.325376 PSD95pdz3_A347E,PSD95pdz3_347,PSD95pdz3,PSD95pdz3,P31016,0.325417,NO,347,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.307,-3.122,1.815,4.89689,,,,,15.176,,,,OHA,-1.269,0.0758425,0.00074525,0.325417 kka2_1:2_D127A,kka2_1:2_127,Kka2,kka2_1:2,P00552,0.325454,NO,127,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.364,-2.492,1.128,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.295029,0.00660501,0.325454 beta-lactamase_2500_I93S,beta-lactamase_2500_93,TEM-1,beta-lactamase_2500,P62593,0.325529,NO,93,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.401,-3.663,2.262,,0.128,E,B,0.48,0.44,19.374,19.374,67.83,BHB,-1.873,0.361275,0.00527066,0.325529 kka2_1:1_D101F,kka2_1:1_101,Kka2,kka2_1:1,P00552,0.325547,NO,101,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.028,-4.345,3.317,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.520039,0.00423361,0.325547 beta-lactamase_625_E210P,beta-lactamase_625_210,TEM-1,beta-lactamase_625,P62593,0.325549,NO,210,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.319,-4.023,1.704,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.213352,0.00663582,0.325549 kka2_1:1_L184I,kka2_1:1_184,Kka2,kka2_1:1,P00552,0.325601,NO,184,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.496,-2.585,1.089,,0.489,E,B,0.55,-0.06,19.127,19.127,63.26,AHH,-1.24833,0.520039,0.00518742,0.325601 beta-lactamase_2500_S241K,beta-lactamase_2500_241,TEM-1,beta-lactamase_2500,P62593,0.325602,NO,241,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.361275,0.00452736,0.325602 kka2_1:4_D261L,kka2_1:4_261,Kka2,kka2_1:4,P00552,0.325605,NO,261,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.708,-3.836,3.128,,0.146,G,A,0.75,-0.33,,,,HAA,-0.759333,0.168804,0.0224846,0.325605 kka2_1:2_R147P,kka2_1:2_147,Kka2,kka2_1:2,P00552,0.325633,NO,147,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.123,-3.991,2.868,,0.094,H,A,1.2,0.97,0.425,,64.02,PBH,-1.98267,0.295029,0.00549168,0.325633 kka2_1:4_F133K,kka2_1:4_133,Kka2,kka2_1:4,P00552,0.325663,NO,133,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-0.871,-3.933,3.062,,0.178,.,B,0.58,0.43,0.786,,42.42,OHA,-0.871667,0.168804,0.00182168,0.325663 kka2_1:2_C131W,kka2_1:2_131,Kka2,kka2_1:2,P00552,0.325685,NO,131,C,W,CW,Special,Hydrophobic,5.07,5.89,0.82,215,121,204,83,108.5,227.8,119.3,-0.831,-5.126,4.295,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.295029,0.00170814,0.325685 kka2_1:1_M148A,kka2_1:1_148,Kka2,kka2_1:1,P00552,0.325691,NO,148,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.847,-2.283,0.436,,0.268,H,A,1.59,0.71,4.618,,64.39,BHA,-1.65467,0.520039,0.00982664,0.325691 kka2_1:1_S32Q,kka2_1:1_32,Kka2,kka2_1:1,P00552,0.325739,NO,32,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-0.804,-3.703,2.899,,0.768,S,b,0.27,3.75,,,,OPA,-1.74533,0.520039,0.00149998,0.325739 kka2_1:4_H188W,kka2_1:4_188,Kka2,kka2_1:4,P00552,0.32575,NO,188,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-0.913,-5.149,4.236,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.168804,0.00273139,0.32575 kka2_1:4_G245M,kka2_1:4_245,Kka2,kka2_1:4,P00552,0.325805,NO,245,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.812,-4.937,4.125,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.168804,0.00683899,0.325805 kka2_1:1_A222I,kka2_1:1_222,Kka2,kka2_1:1,P00552,0.325806,NO,222,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.725,-3.589,2.864,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.520039,0.00207657,0.325806 kka2_1:1_D183Y,kka2_1:1_183,Kka2,kka2_1:1,P00552,0.325846,NO,183,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.204,-4.387,3.183,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.520039,0.00426304,0.325846 beta-lactamase_A123D,beta-lactamase_123,TEM-1,beta-lactamase,P62593,0.325889,NO,123,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.834,-3.743,2.909,4.70061,0.039,H,A,0.52,-0.72,0.705,,41.26,PHH,-1.47367,0.221079,0.0010157,0.325889 beta-lactamase_R241W,beta-lactamase_241,TEM-1,beta-lactamase,P62593,0.325889,NO,241,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.433,-5.399,3.966,5.02621,0.094,E,B,0.68,-0.16,1.327,,50,PBO,-1.42967,0.221079,0.00452736,0.325889 kka2_1:1_E17P,kka2_1:1_17,Kka2,kka2_1:1,P00552,0.325906,NO,17,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.154,-2.799,0.645,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.520039,0.00688738,0.325906 beta-lactamase_2500_A123P,beta-lactamase_2500_123,TEM-1,beta-lactamase_2500,P62593,0.325917,NO,123,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.834,-3.704,2.87,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.361275,0.0010157,0.325917 kka2_1:2_L193A,kka2_1:2_193,Kka2,kka2_1:2,P00552,0.325965,NO,193,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.983,-3.189,2.206,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.295029,0.00480179,0.325965 kka2_1:1_R140D,kka2_1:1_140,Kka2,kka2_1:1,P00552,0.325979,NO,140,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.351,-3.692,2.341,,0.12,H,A,1.2,0.2,11.345,11.345,53.03,BBH,-1.885,0.520039,0.00430167,0.325979 beta-lactamase_2500_A123D,beta-lactamase_2500_123,TEM-1,beta-lactamase_2500,P62593,0.325989,NO,123,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.834,-3.743,2.909,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.361275,0.0010157,0.325989 kka2_1:4_R66V,kka2_1:4_66,Kka2,kka2_1:4,P00552,0.326024,NO,66,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-0.922,-3.78,2.858,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.168804,0.00161025,0.326024 kka2_1:1_R226P,kka2_1:1_226,Kka2,kka2_1:1,P00552,0.326038,NO,226,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.392,-4.085,2.693,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.520039,0.0108032,0.326038 kka2_1:1_G205E,kka2_1:1_205,Kka2,kka2_1:1,P00552,0.326172,NO,205,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.596,-3.693,3.097,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.520039,0.00221855,0.326172 kka2_1:1_E230L,kka2_1:1_230,Kka2,kka2_1:1,P00552,0.326201,NO,230,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.672,-3.572,0.9,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.520039,0.00920051,0.326201 beta-lactamase_2500_L223G,beta-lactamase_2500_223,TEM-1,beta-lactamase_2500,P62593,0.326203,NO,223,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.055,-3.765,2.71,,0.27,,B,0.55,0.09,1.334,,74.48,HHO,-1.35033,0.361275,0.00372793,0.326203 kka2_1:4_P109S,kka2_1:4_109,Kka2,kka2_1:4,P00552,0.326234,NO,109,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.412,-2.854,1.442,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.168804,0.0070929,0.326234 beta-lactamase_2500_G249C,beta-lactamase_2500_249,TEM-1,beta-lactamase_2500,P62593,0.326257,NO,249,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.312,,,,0.256,S,B,0.23,0.04,30.841,30.841,72.73,HOO,-1.81367,0.361275,0.00220169,0.326257 kka2_1:1_T72K,kka2_1:1_72,Kka2,kka2_1:1,P00552,0.326269,NO,72,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.38,-2.635,0.255,,0.784,H,A,0.22,0.29,10.43,10.43,65.53,HPP,-2.238,0.520039,0.00750756,0.326269 kka2_1:1_L102V,kka2_1:1_102,Kka2,kka2_1:1,P00552,0.326287,NO,102,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.804,-2.905,2.101,,,T,A,0.55,-1.17,4.258,,42.42,AHH,-1.398,0.520039,0.00201332,0.326287 kka2_1:8_G210E,kka2_1:8_210,Kka2,kka2_1:8,P00552,0.326388,NO,210,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.095,-3.693,2.598,,0.103,T,A,0.75,-0.62,2.687,,50,OOB,-0.966667,0.100394,0.00598378,0.326388 kka2_1:8_G210E,kka2_1:8_210,Kka2,kka2_1:8,P00552,0.326388,NO,210,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.095,-3.693,2.598,,0.103,T,A,0.75,-0.62,2.687,,50,OOB,-0.966667,0.100394,0.00598378,0.326388 kka2_1:8_V198D,kka2_1:8_198,Kka2,kka2_1:8,P00552,0.326388,NO,198,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.719,-3.799,2.08,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.100394,0.00835002,0.326388 kka2_1:8_V198D,kka2_1:8_198,Kka2,kka2_1:8,P00552,0.326388,NO,198,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.719,-3.799,2.08,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.100394,0.00835002,0.326388 kka2_1:4_Q100W,kka2_1:4_100,Kka2,kka2_1:4,P00552,0.326449,NO,100,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.77,-5.568,2.798,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.168804,0.0066405,0.326449 kka2_1:1_F203C,kka2_1:1_203,Kka2,kka2_1:1,P00552,0.326485,NO,203,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-0.911,-4.889,3.978,,0.26,E,B,0.58,-0.92,7.323,,63.64,BHP,-1.34167,0.520039,0.00318738,0.326485 kka2_1:2_F256P,kka2_1:2_256,Kka2,kka2_1:2,P00552,0.326526,NO,256,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.49,-4.358,2.868,,,H,A,0.58,-0.78,1.653,,53.03,HHH,-1.423,0.295029,0.0132841,0.326526 beta-lactamase_2500_Y95G,beta-lactamase_2500_95,TEM-1,beta-lactamase_2500,P62593,0.326538,NO,95,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-1.715,-3.781,2.066,,0.122,,b,0.21,-0.37,2.914,,77.62,BHP,-2.16167,0.361275,0.00479449,0.326538 PSD95pdz3_H372R,PSD95pdz3_372,PSD95pdz3,PSD95pdz3,P31016,0.326601,NO,372,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-1.627,-3.165,1.538,5.5607,,,,,17.008,,,,PBA,-1.63033,0.0758425,0.00040301,0.326601 kka2_1:1_L94K,kka2_1:1_94,Kka2,kka2_1:1,P00552,0.326605,NO,94,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.618,-3.731,2.113,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.520039,0.00520888,0.326605 kka2_1:2_L212T,kka2_1:2_212,Kka2,kka2_1:2,P00552,0.326644,NO,212,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.904,-3.451,2.547,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.295029,0.0031426,0.326644 kka2_1:1_L107D,kka2_1:1_107,Kka2,kka2_1:1,P00552,0.326661,NO,107,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.238,-3.01,1.772,,0.197,.,B,0.55,-1.1,3.542,,71.59,BHH,-2.143,0.520039,0.00561937,0.326661 kka2_1:1_A150R,kka2_1:1_150,Kka2,kka2_1:1,P00552,0.32669,NO,150,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.949,-3.769,2.82,,0.544,T,A,0.46,1.34,2.333,,63.26,AHO,-1.272,0.520039,0.0045009,0.32669 beta-lactamase_2500_G249I,beta-lactamase_2500_249,TEM-1,beta-lactamase_2500,P62593,0.32671,NO,249,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.312,,,,0.256,S,B,0.23,0.04,30.841,30.841,72.73,HOO,-1.81367,0.361275,0.00220169,0.32671 kka2_1:1_W24F,kka2_1:1_24,Kka2,kka2_1:1,P00552,0.32682,NO,24,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-1.779,-2.325,0.546,,0.477,E,B,0.47,-0.21,2.375,,56.06,AHH,-2.24467,0.520039,0.00631564,0.32682 beta-lactamase_156_I258D,beta-lactamase_156_258,TEM-1,beta-lactamase_156,P62593,0.326822,NO,258,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.111618,0.007931,0.326822 kka2_1:1_P179A,kka2_1:1_179,Kka2,kka2_1:1,P00552,0.326826,NO,179,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.974,-2.519,1.545,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.520039,0.00298346,0.326826 beta-lactamase_625_G281H,beta-lactamase_625_281,TEM-1,beta-lactamase_625,P62593,0.326858,NO,281,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.213352,0.0406482,0.326858 beta-lactamase_2500_Y262T,beta-lactamase_2500_262,TEM-1,beta-lactamase_2500,P62593,0.326908,NO,262,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-1.332,-4.271,2.939,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.361275,0.00853516,0.326908 beta-lactamase_2500_L73N,beta-lactamase_2500_73,TEM-1,beta-lactamase_2500,P62593,0.326912,NO,73,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.507,-4.234,2.727,,,H,A,0.55,-0.64,2.178,,67.83,HHH,-1.487,0.361275,0.00488983,0.326912 beta-lactamase_39_T263P,beta-lactamase_39_263,TEM-1,beta-lactamase_39,P62593,0.32693,NO,263,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.0495842,0.0110582,0.32693 kka2_1:4_G201I,kka2_1:4_201,Kka2,kka2_1:4,P00552,0.326931,NO,201,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.56,-4.262,2.702,,0.149,T,l,0.29,-0.57,0.284,,52.65,POB,-1.92233,0.168804,0.00820117,0.326931 beta-lactamase_R255Y,beta-lactamase_255,TEM-1,beta-lactamase,P62593,0.327053,NO,255,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.266,-2.384,0.118,5.55882,0.141,E,B,0.68,0.38,1.199,,63.99,PBH,-2.00433,0.221079,0.00499612,0.327053 beta-lactamase_625_D83Y,beta-lactamase_625_83,TEM-1,beta-lactamase_625,P62593,0.32706,NO,83,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.066,-4.396,3.33,,0.354,H,A,0.75,0.22,0.239,,48.95,HAH,-1.34733,0.213352,0.00205968,0.32706 Pab1_F129V,Pab1_129,Pab1,Pab1,P04147,0.32707,NO,129,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.269,-3.174,1.905,,0.219,E,B,0.03,-0.07,1.307,,73.83,HHH,-1.27533,0.175299,0.000625182,0.32707 Pab1_I137P,Pab1_137,Pab1,Pab1,P04147,0.327123,NO,137,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.212,-3.922,2.71,,0.068,,B,0.77,0.35,,,,AHA,-1.314,0.175299,0.000342224,0.327123 kka2_1:2_L47S,kka2_1:2_47,Kka2,kka2_1:2,P00552,0.327128,NO,47,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.265,-3.626,2.361,,0.139,E,B,0.55,-0.86,2.369,,63.26,HHH,-1.77933,0.295029,0.00509386,0.327128 kka2_1:8_D208K,kka2_1:8_208,Kka2,kka2_1:8,P00552,0.327154,NO,208,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.708,-3.485,2.777,,0.36,,l,0.29,-1.01,,,,HAO,-0.929667,0.100394,0.00212588,0.327154 kka2_1:8_D208K,kka2_1:8_208,Kka2,kka2_1:8,P00552,0.327154,NO,208,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.708,-3.485,2.777,,0.36,,l,0.29,-1.01,,,,HAO,-0.929667,0.100394,0.00212588,0.327154 kka2_1:4_G30W,kka2_1:4_30,Kka2,kka2_1:4,P00552,0.327362,NO,30,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.596,-5.126,4.53,,0.54,S,g,0.29,3.76,,,,HOO,-1.51133,0.168804,0.00159208,0.327362 beta-lactamase_T178L,beta-lactamase_178,TEM-1,beta-lactamase,P62593,0.327366,NO,178,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-0.791,-3.133,2.342,5.06452,0.029,E,B,0.3,-1.07,,,,APP,-0.947667,0.221079,0.000684366,0.327366 kka2_1:2_F203R,kka2_1:2_203,Kka2,kka2_1:2,P00552,0.32737,NO,203,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-0.911,-4.185,3.274,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.295029,0.00318738,0.32737 kka2_1:1_P76S,kka2_1:1_76,Kka2,kka2_1:1,P00552,0.32739,NO,76,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.449,-2.672,1.223,,0.331,.,B,0.52,-0.41,0.345,,63.64,HOO,-1.662,0.520039,0.00625685,0.32739 kka2_1:1_A34L,kka2_1:1_34,Kka2,kka2_1:1,P00552,0.327424,NO,34,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.928,-3.244,2.316,,0.417,.,B,0.46,2.29,0.262,,52.27,AHH,-1.747,0.520039,0.00343484,0.327424 kka2_1:1_L107Y,kka2_1:1_107,Kka2,kka2_1:1,P00552,0.327432,NO,107,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.238,-4.146,2.908,,0.197,.,B,0.55,-1.1,3.542,,71.59,BHH,-2.143,0.520039,0.00561937,0.327432 kka2_1:1_I228N,kka2_1:1_228,Kka2,kka2_1:1,P00552,0.327443,NO,228,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.142,-4.223,3.081,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.520039,0.00458834,0.327443 beta-lactamase_625_F64Q,beta-lactamase_625_64,TEM-1,beta-lactamase_625,P62593,0.327448,NO,64,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-0.841,-4.349,3.508,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.213352,0.000947691,0.327448 beta-lactamase_V78N,beta-lactamase_78,TEM-1,beta-lactamase,P62593,0.32747,NO,78,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.459,-4.189,2.73,4.79197,,H,A,0.96,-0.47,1.132,,63.64,HHH,-1.17833,0.221079,0.00492501,0.32747 beta-lactamase_625_M209I,beta-lactamase_625_209,TEM-1,beta-lactamase_625,P62593,0.327474,NO,209,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.442,-3.121,1.679,,,H,A,0.55,-0.97,1.167,,64.69,HHA,-1.52633,0.213352,0.00625021,0.327474 kka2_1:2_Y257M,kka2_1:2_257,Kka2,kka2_1:2,P00552,0.327537,NO,257,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-1.064,-4.488,3.424,,0.022,H,A,0.21,-0.88,0.833,,52.65,HHB,-1.39333,0.295029,0.0148191,0.327537 kka2_1:8_F171K,kka2_1:8_171,Kka2,kka2_1:8,P00552,0.327664,NO,171,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.326,-3.945,2.619,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.100394,0.00821426,0.327664 kka2_1:8_F171K,kka2_1:8_171,Kka2,kka2_1:8,P00552,0.327664,NO,171,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.326,-3.945,2.619,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.100394,0.00821426,0.327664 kka2_1:1_E111H,kka2_1:1_111,Kka2,kka2_1:1,P00552,0.327711,NO,111,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.28,-3.298,1.018,,0.155,H,A,1.52,-1.14,15.716,15.716,65.53,HAB,-2.27833,0.520039,0.00746789,0.327711 kka2_1:2_V185D,kka2_1:2_185,Kka2,kka2_1:2,P00552,0.327783,NO,185,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.045,-4.011,2.966,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.295029,0.00367031,0.327783 kka2_1:4_L174Y,kka2_1:4_174,Kka2,kka2_1:4,P00552,0.327799,NO,174,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.952,-4.056,3.104,,,H,A,0.55,-0.31,1.339,,51.89,BHB,-2.08533,0.168804,0.00438501,0.327799 kka2_1:2_Q219S,kka2_1:2_219,Kka2,kka2_1:2,P00552,0.3278,NO,219,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-0.93,-3.233,2.303,,0.088,H,A,0.4,-0.85,1.917,,50,HPA,-1.05167,0.295029,0.00237913,0.3278 kka2_1:4_F37G,kka2_1:4_37,Kka2,kka2_1:4,P00552,0.32784,NO,37,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.427,-3.622,2.195,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.168804,0.00586193,0.32784 kka2_1:1_W69Y,kka2_1:1_69,Kka2,kka2_1:1,P00552,0.327891,NO,69,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-0.859,-2.519,1.66,,0.164,H,A,0.47,0.15,5.074,,38.64,PHH,-1.49967,0.520039,0.0012874,0.327891 kka2_1:1_H162Q,kka2_1:1_162,Kka2,kka2_1:1,P00552,0.327925,NO,162,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-2.319,-3.703,1.384,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.520039,0.00616145,0.327925 beta-lactamase_2500_F64V,beta-lactamase_2500_64,TEM-1,beta-lactamase_2500,P62593,0.327985,NO,64,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-0.841,-3.304,2.463,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.361275,0.000947691,0.327985 beta-lactamase_2500_L137G,beta-lactamase_2500_137,TEM-1,beta-lactamase_2500,P62593,0.328024,NO,137,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.03,-3.837,2.807,,,H,A,0.55,-0.38,0.769,,42.31,HHP,-1.58933,0.361275,0.00278599,0.328024 beta-lactamase_2500_P105D,beta-lactamase_2500_105,TEM-1,beta-lactamase_2500,P62593,0.328042,NO,105,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.813,-3.466,2.653,,0.226,T,A,0.52,0.8,3.1,,63.29,POH,-1.01533,0.361275,0.0011981,0.328042 kka2_1:2_F203E,kka2_1:2_203,Kka2,kka2_1:2,P00552,0.328123,NO,203,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-0.911,-3.952,3.041,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.295029,0.00318738,0.328123 kka2_1:1_I29R,kka2_1:1_29,Kka2,kka2_1:1,P00552,0.328248,NO,29,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.692,-4.083,2.391,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.520039,0.00619521,0.328248 beta-lactamase_625_G240Q,beta-lactamase_625_240,TEM-1,beta-lactamase_625,P62593,0.328293,NO,240,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.213352,0.00591201,0.328293 kka2_1:1_S32P,kka2_1:1_32,Kka2,kka2_1:1,P00552,0.328293,NO,32,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-0.804,-3.683,2.879,,0.768,S,b,0.27,3.75,,,,OPA,-1.74533,0.520039,0.00149998,0.328293 kka2_1:1_G189S,kka2_1:1_189,Kka2,kka2_1:1,P00552,0.328351,NO,189,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.596,-3.189,2.593,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.520039,0.00253688,0.328351 beta-lactamase_2500_D83H,beta-lactamase_2500_83,TEM-1,beta-lactamase_2500,P62593,0.328408,NO,83,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.066,-4.503,3.437,,0.354,H,A,0.75,0.22,0.239,,48.95,HAH,-1.34733,0.361275,0.00205968,0.328408 beta-lactamase_G248C,beta-lactamase_248,TEM-1,beta-lactamase,P62593,0.328467,NO,248,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.794,-5.025,3.231,4.69798,,E,b,0.23,-0.43,1.782,,61.19,HOO,-1.52867,0.221079,0.00428493,0.328467 beta-lactamase_156_T179G,beta-lactamase_156_179,TEM-1,beta-lactamase_156,P62593,0.328471,NO,179,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.085,-3.296,2.211,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.111618,0.00226045,0.328471 kka2_1:4_L223N,kka2_1:4_223,Kka2,kka2_1:4,P00552,0.328476,NO,223,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.861,-4.196,3.335,,,H,A,1.59,-1.24,1.268,,50,HHH,-0.854333,0.168804,0.00253574,0.328476 kka2_1:1_G210T,kka2_1:1_210,Kka2,kka2_1:1,P00552,0.328496,NO,210,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.095,-3.513,2.418,,0.103,T,A,0.29,-0.62,14.483,14.483,50,OOB,-0.966667,0.520039,0.00598378,0.328496 kka2_1:1_C31E,kka2_1:1_31,Kka2,kka2_1:1,P00552,0.328528,NO,31,C,E,CE,Special,negativeCharge,5.07,3.22,-1.85,170,121,147,26,108.5,138.4,29.9,-2.246,-1.966,-0.28,,1.152,S,b,0.46,4.16,8.272,,63.26,OOP,-1.21533,0.520039,0.00681582,0.328528 kka2_1:2_Q219C,kka2_1:2_219,Kka2,kka2_1:2,P00552,0.328655,NO,219,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-0.93,-5.139,4.209,,0.088,H,A,0.4,-0.85,1.917,,50,HPA,-1.05167,0.295029,0.00237913,0.328655 kka2_1:4_K112C,kka2_1:4_112,Kka2,kka2_1:4,P00552,0.328677,NO,112,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-2.491,-3.546,1.055,,0.076,H,A,2.34,-1.37,0.39,,56.06,ABH,-2.00133,0.168804,0.00645389,0.328677 kka2_1:2_L39Q,kka2_1:2_39,Kka2,kka2_1:2,P00552,0.328708,NO,39,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.223,-4.313,3.09,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.295029,0.00493618,0.328708 beta-lactamase_625_D129E,beta-lactamase_625_129,TEM-1,beta-lactamase_625,P62593,0.328749,NO,129,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.816,-2.232,1.416,,,,B,0.75,-0.69,0.171,,34.97,PAP,-0.818,0.213352,0.00109178,0.328749 beta-lactamase_2500_A185D,beta-lactamase_2500_185,TEM-1,beta-lactamase_2500,P62593,0.328755,NO,185,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.406,-3.867,2.461,,,H,A,0.46,-1.02,2.999,,65.03,HHP,-1.84033,0.361275,0.00467449,0.328755 kka2_1:4_C209K,kka2_1:4_209,Kka2,kka2_1:4,P00552,0.328828,NO,209,C,K,CK,Special,PositiveCharge,5.07,9.74,4.67,202,121,146,25,108.5,168.6,60.1,-0.906,-3.933,3.027,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.168804,0.00260862,0.328828 beta-lactamase_625_R220W,beta-lactamase_625_220,TEM-1,beta-lactamase_625,P62593,0.328848,NO,220,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-0.942,-5.348,4.406,,0.295,I,A,1.2,-0.76,5.086,,74.48,HBP,-1.33633,0.213352,0.00232421,0.328848 Pab1_K156E,Pab1_156,Pab1,Pab1,P04147,0.328848,NO,156,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.083,-2.807,1.724,,0.406,E,B,1.82,-0.26,,,,PBH,-1.58167,0.175299,0.000316767,0.328848 beta-lactamase_2500_L79C,beta-lactamase_2500_79,TEM-1,beta-lactamase_2500,P62593,0.328859,NO,79,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.842,-4.663,3.821,,0.007,H,A,0.55,-0.16,0.823,,50.35,HHP,-1.44333,0.361275,0.000947397,0.328859 beta-lactamase_2500_R91Y,beta-lactamase_2500_91,TEM-1,beta-lactamase_2500,P62593,0.328901,NO,91,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.392,-4.246,2.854,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.361275,0.00380226,0.328901 beta-lactamase_625_R257N,beta-lactamase_625_257,TEM-1,beta-lactamase_625,P62593,0.328928,NO,257,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.213352,0.00756629,0.328928 kka2_1:1_F133W,kka2_1:1_133,Kka2,kka2_1:1,P00552,0.328968,NO,133,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-0.871,-4.449,3.578,,0.178,.,B,0.58,0.43,1.999,,42.42,OHA,-0.871667,0.520039,0.00182168,0.328968 kka2_1:1_A215F,kka2_1:1_215,Kka2,kka2_1:1,P00552,0.329013,NO,215,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.968,-4.18,3.212,,0.039,E,B,0.46,-0.59,0.754,,50.38,HHA,-1.00467,0.520039,0.00529129,0.329013 beta-lactamase_2500_T131E,beta-lactamase_2500_131,TEM-1,beta-lactamase_2500,P62593,0.32907,NO,131,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.328,-3.523,2.195,,,H,A,0.22,-0.69,3.048,,67.48,PPH,-1.00867,0.361275,0.00345886,0.32907 beta-lactamase_A230T,beta-lactamase_230,TEM-1,beta-lactamase,P62593,0.329092,NO,230,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.154,-3.381,2.227,4.54336,0.01,E,B,0.75,-1.17,1.97,,50,HHA,-1.079,0.221079,0.00516841,0.329092 beta-lactamase_625_A247D,beta-lactamase_625_247,TEM-1,beta-lactamase_625,P62593,0.329102,NO,247,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.213352,0.00611275,0.329102 kka2_1:2_L93A,kka2_1:2_93,Kka2,kka2_1:2,P00552,0.329107,NO,93,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.815,-3.129,2.314,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.295029,0.00131498,0.329107 beta-lactamase_2500_A123H,beta-lactamase_2500_123,TEM-1,beta-lactamase_2500,P62593,0.329199,NO,123,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.834,-4.729,3.895,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.361275,0.0010157,0.329199 PSD95pdz3_R354P,PSD95pdz3_354,PSD95pdz3,PSD95pdz3,P31016,0.329218,NO,354,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.582,-3.561,1.979,6.21887,,,,,23.7791,,,,HBB,-1.44833,0.0758425,0.000650924,0.329218 kka2_1:2_L212Y,kka2_1:2_212,Kka2,kka2_1:2,P00552,0.329219,NO,212,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.904,-4.048,3.144,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.295029,0.0031426,0.329219 beta-lactamase_2500_W208K,beta-lactamase_2500_208,TEM-1,beta-lactamase_2500,P62593,0.329238,NO,208,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-0.818,-3.907,3.089,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.361275,0.00126609,0.329238 kka2_1:4_L184G,kka2_1:4_184,Kka2,kka2_1:4,P00552,0.329248,NO,184,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.496,-3.006,1.51,,0.489,E,B,1.59,-0.06,4.495,,63.26,AHH,-1.24833,0.168804,0.00518742,0.329248 kka2_1:2_F133K,kka2_1:2_133,Kka2,kka2_1:2,P00552,0.329255,NO,133,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-0.871,-3.933,3.062,,0.178,.,B,0.58,0.43,1.999,,42.42,OHA,-0.871667,0.295029,0.00182168,0.329255 kka2_1:1_D250R,kka2_1:1_250,Kka2,kka2_1:1,P00552,0.329288,NO,250,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.015,-3.871,2.856,,0.274,.,b,0.75,-0.46,4.177,,51.89,OAP,-1.83933,0.520039,0.0177103,0.329288 kka2_1:1_C131N,kka2_1:1_131,Kka2,kka2_1:1,P00552,0.329302,NO,131,C,N,CN,Special,Polar,5.07,5.47157,0.401575,139,121,132,11,108.5,114.1,5.6,-0.831,-4.151,3.32,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.520039,0.00170814,0.329302 kka2_1:1_A108W,kka2_1:1_108,Kka2,kka2_1:1,P00552,0.329373,NO,108,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.061,-5.601,3.54,,0.243,.,B,0.46,-1.34,3.156,,71.59,HHO,-1.57033,0.520039,0.00751209,0.329373 kka2_1:2_R211D,kka2_1:2_211,Kka2,kka2_1:2,P00552,0.329395,NO,211,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-0.899,-3.783,2.884,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.295029,0.00204888,0.329395 kka2_1:2_A119L,kka2_1:2_119,Kka2,kka2_1:2,P00552,0.329399,NO,119,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.073,-3.266,2.193,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.295029,0.00441074,0.329399 kka2_1:1_G95Y,kka2_1:1_95,Kka2,kka2_1:1,P00552,0.329427,NO,95,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-2.403,-4.397,1.994,,0.126,E,B,0.29,-0.74,7.822,,71.59,HOA,-2.198,0.520039,0.00743616,0.329427 kka2_1:4_A222I,kka2_1:4_222,Kka2,kka2_1:4,P00552,0.32945,NO,222,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.725,-3.589,2.864,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.168804,0.00207657,0.32945 kka2_1:2_G205T,kka2_1:2_205,Kka2,kka2_1:2,P00552,0.329454,NO,205,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.596,-3.675,3.079,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.295029,0.00221855,0.329454 kka2_1:1_G201I,kka2_1:1_201,Kka2,kka2_1:1,P00552,0.329498,NO,201,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.56,-4.262,2.702,,0.149,T,l,0.29,-0.57,16.092,16.092,52.65,POB,-1.92233,0.520039,0.00820117,0.329498 kka2_1:2_P167N,kka2_1:2_167,Kka2,kka2_1:2,P00552,0.329509,NO,167,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-2.403,-3.993,1.59,,0.18,H,A,0.52,0.75,3.6,,64.39,HOH,-2.26633,0.295029,0.00543203,0.329509 beta-lactamase_625_A124Q,beta-lactamase_625_124,TEM-1,beta-lactamase_625,P62593,0.329518,NO,124,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.181,-4.004,2.823,,,H,A,0.46,-0.9,2.027,,64.34,HHH,-1.152,0.213352,0.00481399,0.329518 kka2_1:2_R211K,kka2_1:2_211,Kka2,kka2_1:2,P00552,0.329531,NO,211,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-0.899,-2.904,2.005,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.295029,0.00204888,0.329531 kka2_1:2_R147I,kka2_1:2_147,Kka2,kka2_1:2,P00552,0.329584,NO,147,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.123,-4.139,3.016,,0.094,H,A,1.2,0.97,0.425,,64.02,PBH,-1.98267,0.295029,0.00549168,0.329584 kka2_1:4_D220H,kka2_1:4_220,Kka2,kka2_1:4,P00552,0.329605,NO,220,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.787,-4.544,3.757,,,H,A,0.75,-1.14,1.237,,46.59,PAH,-1.152,0.168804,0.00158066,0.329605 kka2_1:4_E262D,kka2_1:4_262,Kka2,kka2_1:4,P00552,0.329608,NO,262,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-0.829,-2.883,2.054,,0.059,G,A,1.04,-0.18,2.383,,42.42,AAH,-0.816,0.168804,0.0191586,0.329608 kka2_1:2_L184G,kka2_1:2_184,Kka2,kka2_1:2,P00552,0.32961,NO,184,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.496,-3.006,1.51,,0.489,E,B,0.55,-0.06,14.044,14.044,63.26,AHH,-1.24833,0.295029,0.00518742,0.32961 beta-lactamase_2500_L197D,beta-lactamase_2500_197,TEM-1,beta-lactamase_2500,P62593,0.329618,NO,197,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.853,-4.107,3.254,,0.007,S,B,0.55,0.33,2.421,,60.14,HHP,-1.833,0.361275,0.00144602,0.329618 kka2_1:2_D157V,kka2_1:2_157,Kka2,kka2_1:2,P00552,0.329649,NO,157,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.993,-3.837,2.844,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.295029,0.0042313,0.329649 kka2_1:2_Y257G,kka2_1:2_257,Kka2,kka2_1:2,P00552,0.329672,NO,257,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-1.064,-3.67,2.606,,0.022,H,A,0.21,-0.88,0.833,,52.65,HHB,-1.39333,0.295029,0.0148191,0.329672 kka2_1:8_F203I,kka2_1:8_203,Kka2,kka2_1:8,P00552,0.329695,NO,203,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-0.911,-3.319,2.408,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.100394,0.00318738,0.329695 kka2_1:8_F203I,kka2_1:8_203,Kka2,kka2_1:8,P00552,0.329695,NO,203,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-0.911,-3.319,2.408,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.100394,0.00318738,0.329695 beta-lactamase_2500_D48M,beta-lactamase_2500_48,TEM-1,beta-lactamase_2500,P62593,0.329721,NO,48,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.101,-4.896,3.795,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.361275,0.0027273,0.329721 kka2_1:1_P194S,kka2_1:1_194,Kka2,kka2_1:1,P00552,0.32974,NO,194,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.846,-2.623,1.777,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.520039,0.00314194,0.32974 beta-lactamase_A34R,beta-lactamase_34,TEM-1,beta-lactamase,P62593,0.329785,NO,34,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.059,-4.061,2.002,4.9129,,H,A,0.75,-0.54,3.614,,73.78,AHA,-1.74967,0.221079,0.00407913,0.329785 kka2_1:8_G205M,kka2_1:8_205,Kka2,kka2_1:8,P00552,0.329796,NO,205,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.596,-4.958,4.362,,,E,b,0.75,-1.05,,,,POH,-1.09933,0.100394,0.00221855,0.329796 kka2_1:8_G205M,kka2_1:8_205,Kka2,kka2_1:8,P00552,0.329796,NO,205,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.596,-4.958,4.362,,,E,b,0.75,-1.05,,,,POH,-1.09933,0.100394,0.00221855,0.329796 kka2_1:1_T85P,kka2_1:1_85,Kka2,kka2_1:1,P00552,0.329805,NO,85,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.165,-4.057,1.892,,0.576,E,B,0.82,1.39,16.653,16.653,71.59,HPA,-2.10133,0.520039,0.00634493,0.329805 beta-lactamase_625_D48W,beta-lactamase_625_48,TEM-1,beta-lactamase_625,P62593,0.329859,NO,48,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.101,-5.502,4.401,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.213352,0.0027273,0.329859 kka2_1:2_G205I,kka2_1:2_205,Kka2,kka2_1:2,P00552,0.329863,NO,205,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.596,-4.264,3.668,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.295029,0.00221855,0.329863 beta-lactamase_625_G52I,beta-lactamase_625_52,TEM-1,beta-lactamase_625,P62593,0.329893,NO,52,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.149,-4.163,3.014,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.213352,0.00340138,0.329893 kka2_1:1_F171G,kka2_1:1_171,Kka2,kka2_1:1,P00552,0.329926,NO,171,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.326,-3.793,2.467,,0.154,H,A,1.62,-0.1,13.679,13.679,63.64,HHH,-1.45433,0.520039,0.00821426,0.329926 kka2_1:2_Y244D,kka2_1:2_244,Kka2,kka2_1:2,P00552,0.329941,NO,244,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-0.775,-3.947,3.172,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.295029,0.00453187,0.329941 kka2_1:8_D190T,kka2_1:8_190,Kka2,kka2_1:8,P00552,0.329954,NO,190,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.708,-3.45,2.742,,0.213,S,b,0.29,-0.82,,,,OAH,-0.711667,0.100394,0.00247989,0.329954 kka2_1:8_D190T,kka2_1:8_190,Kka2,kka2_1:8,P00552,0.329954,NO,190,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.708,-3.45,2.742,,0.213,S,b,0.29,-0.82,,,,OAH,-0.711667,0.100394,0.00247989,0.329954 beta-lactamase_625_G240R,beta-lactamase_625_240,TEM-1,beta-lactamase_625,P62593,0.329957,NO,240,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.213352,0.00591201,0.329957 beta-lactamase_625_L146H,beta-lactamase_625_146,TEM-1,beta-lactamase_625,P62593,0.32996,NO,146,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.462,-4.92,3.458,,0.007,H,A,0.55,-0.56,2.16,,64.69,AHP,-1.656,0.213352,0.00474542,0.32996 beta-lactamase_2500_P105C,beta-lactamase_2500_105,TEM-1,beta-lactamase_2500,P62593,0.329965,NO,105,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.813,-5.05,4.237,,0.226,T,A,0.52,0.8,3.1,,63.29,POH,-1.01533,0.361275,0.0011981,0.329965 kka2_1:1_D261N,kka2_1:1_261,Kka2,kka2_1:1,P00552,0.329982,NO,261,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.708,-3.251,2.543,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.520039,0.0224846,0.329982 kka2_1:2_S32Q,kka2_1:2_32,Kka2,kka2_1:2,P00552,0.330012,NO,32,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-0.804,-3.703,2.899,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.295029,0.00149998,0.330012 kka2_1:8_A117D,kka2_1:8_117,Kka2,kka2_1:8,P00552,0.33005,NO,117,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.828,-3.786,2.958,,,H,A,1.04,-0.78,0.755,,45.83,HHA,-1.79333,0.100394,0.00282984,0.33005 kka2_1:8_A117D,kka2_1:8_117,Kka2,kka2_1:8,P00552,0.33005,NO,117,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.828,-3.786,2.958,,,H,A,1.04,-0.78,0.755,,45.83,HHA,-1.79333,0.100394,0.00282984,0.33005 beta-lactamase_156_A230Q,beta-lactamase_156_230,TEM-1,beta-lactamase_156,P62593,0.330063,NO,230,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.154,-4.025,2.871,,0.01,E,B,0.46,-1.17,2.179,,50,HHA,-1.079,0.111618,0.00516841,0.330063 kka2_1:8_R145P,kka2_1:8_145,Kka2,kka2_1:8,P00552,0.330075,NO,145,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.804,-4.038,2.234,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.100394,0.00846663,0.330075 kka2_1:8_R145P,kka2_1:8_145,Kka2,kka2_1:8,P00552,0.330075,NO,145,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.804,-4.038,2.234,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.100394,0.00846663,0.330075 kka2_1:1_R258T,kka2_1:1_258,Kka2,kka2_1:1,P00552,0.330087,NO,258,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.626,-2.894,1.268,,0.316,H,A,1.2,-0.85,7.485,7.485,53.03,HBH,-1.25933,0.520039,0.00983174,0.330087 kka2_1:2_V84F,kka2_1:2_84,Kka2,kka2_1:2,P00552,0.330109,NO,84,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-2.279,-4.266,1.987,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.295029,0.00724019,0.330109 kka2_1:8_V84P,kka2_1:8_84,Kka2,kka2_1:8,P00552,0.330201,NO,84,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-2.279,-4.01,1.731,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.100394,0.00724019,0.330201 kka2_1:8_V84P,kka2_1:8_84,Kka2,kka2_1:8,P00552,0.330201,NO,84,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-2.279,-4.01,1.731,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.100394,0.00724019,0.330201 kka2_1:2_Y244V,kka2_1:2_244,Kka2,kka2_1:2,P00552,0.330228,NO,244,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-0.775,-3.332,2.557,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.295029,0.00453187,0.330228 beta-lactamase_625_D129C,beta-lactamase_625_129,TEM-1,beta-lactamase_625,P62593,0.330229,NO,129,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.816,-5.136,4.32,,,,B,0.75,-0.69,0.171,,34.97,PAP,-0.818,0.213352,0.00109178,0.330229 kka2_1:1_Y218H,kka2_1:1_218,Kka2,kka2_1:1,P00552,0.330266,NO,218,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-1.438,-1.83,0.392,,0.122,H,A,1.25,-0.69,3.059,,56.06,BHP,-1.17533,0.520039,0.0126098,0.330266 kka2_1:1_L232R,kka2_1:1_232,Kka2,kka2_1:1,P00552,0.330295,NO,232,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.514,-4.216,2.702,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.520039,0.00800103,0.330295 kka2_1:1_R66Q,kka2_1:1_66,Kka2,kka2_1:1,P00552,0.330324,NO,66,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-0.922,-3.512,2.59,,0.103,H,A,1.2,-0.2,2.659,,46.21,HBH,-1.13567,0.520039,0.00161025,0.330324 beta-lactamase_156_N130L,beta-lactamase_156_130,TEM-1,beta-lactamase_156,P62593,0.330373,NO,130,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-0.798,-3.583,2.785,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.111618,0.000683376,0.330373 kka2_1:2_A237T,kka2_1:2_237,Kka2,kka2_1:2,P00552,0.330434,NO,237,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.12,-2.777,0.657,,0.068,H,A,0.46,-0.71,2.369,,92.05,HHA,-2.10433,0.295029,0.012257,0.330434 beta-lactamase_S104P,beta-lactamase_104,TEM-1,beta-lactamase,P62593,0.330458,NO,104,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.015,-3.751,2.736,4.92365,0.04,,b,0.82,0.57,4.02,,63.29,HPO,-1.05267,0.221079,0.00218083,0.330458 beta-lactamase_S233W,beta-lactamase_233,TEM-1,beta-lactamase,P62593,0.330493,NO,233,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.886,-5.339,3.453,4.98121,0.016,E,B,0.48,-1.01,5.361,,77.62,BPO,-1.17267,0.221079,0.00311415,0.330493 kka2_1:1_L123H,kka2_1:1_123,Kka2,kka2_1:1,P00552,0.330563,NO,123,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.888,-4.956,4.068,,0.007,H,A,0.55,-0.4,1.447,,48.86,BHB,-1.301,0.520039,0.00325188,0.330563 kka2_1:2_G30P,kka2_1:2_30,Kka2,kka2_1:2,P00552,0.33062,NO,30,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.596,-3.908,3.312,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.295029,0.00159208,0.33062 Ubiquitin_G75N,Ubiquitin_75,Uba1,Ubiquitin,P0CG48,0.330645,NO,75,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.613,-3.752,2.139,5.44099,0.552,T,A,0.73,0.9,4.017,,34.31,BOO,-1.66767,0.205827,0.000712673,0.330645 Ubiquitin_G76D,Ubiquitin_76,Uba1,Ubiquitin,P0CG48,0.330645,NO,76,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.651,-3.603,1.952,5.7647,0.23,,B,0.12,0.08,9.665,9.665,34.31,OOO,-1.632,0.205827,0.000653872,0.330645 Ubiquitin_R42F,Ubiquitin_42,Uba1,Ubiquitin,P0CG48,0.330645,NO,42,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.571,-4.15,2.579,5.07805,0.244,E,B,0.68,-0.54,1.976,,72.85,PBH,-1.38967,0.205827,0.000622265,0.330645 Ubiquitin_R72D,Ubiquitin_72,Uba1,Ubiquitin,P0CG48,0.330645,NO,72,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.034,-2.968,0.934,5.19484,0.077,,B,1.41,-0.1,9.638,9.638,42.77,HBH,-1.82733,0.205827,0.000768249,0.330645 Ubiquitin_R74S,Ubiquitin_74,Uba1,Ubiquitin,P0CG48,0.330645,NO,74,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.739,-3.413,1.674,5.6462,0.838,T,A,0.98,3.15,9.119,9.119,34.31,HBO,-1.71767,0.205827,0.000894236,0.330645 E1_Ubiquitin_G75C,E1_Ubiquitin_75,Uba1,E1_Ubiquitin,P0CG63,0.330681,NO,75,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.999,-4.958,3.959,,0.552,T,A,0.75,0.9,4.369,,83.73,BOO,-1.1,0.18783,0.00153276,0.330681 kka2_1:1_A110M,kka2_1:1_110,Kka2,kka2_1:1,P00552,0.330719,NO,110,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.064,-3.65,1.586,,0.175,H,A,1.04,-1.19,11.755,,71.59,OHA,-1.91867,0.520039,0.00759851,0.330719 kka2_1:1_S32K,kka2_1:1_32,Kka2,kka2_1:1,P00552,0.330758,NO,32,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-0.804,-3.26,2.456,,0.768,S,b,0.27,3.75,,,,OPA,-1.74533,0.520039,0.00149998,0.330758 kka2_1:1_E182L,kka2_1:1_182,Kka2,kka2_1:1,P00552,0.33076,NO,182,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.516,-3.646,2.13,,0.326,,B,1.52,0.75,14.547,14.547,65.53,OAA,-1.806,0.520039,0.00641548,0.33076 beta-lactamase_2500_A133K,beta-lactamase_2500_133,TEM-1,beta-lactamase_2500,P62593,0.33077,NO,133,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.186,-3.614,2.428,,,H,A,0.46,-0.86,2.649,,67.83,HHP,-0.988333,0.361275,0.00468022,0.33077 beta-lactamase_625_A132Q,beta-lactamase_625_132,TEM-1,beta-lactamase_625,P62593,0.330773,NO,132,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.9,-3.943,3.043,,,H,A,0.46,-0.93,0.316,,64.69,PHH,-1.138,0.213352,0.000962524,0.330773 beta-lactamase_2500_T178N,beta-lactamase_2500_178,TEM-1,beta-lactamase_2500,P62593,0.330792,NO,178,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-0.791,-3.448,2.657,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.361275,0.000684366,0.330792 kka2_1:4_L170I,kka2_1:4_170,Kka2,kka2_1:4,P00552,0.330812,NO,170,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.28,-2.562,1.282,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.168804,0.00730791,0.330812 kka2_1:1_H135Q,kka2_1:1_135,Kka2,kka2_1:1,P00552,0.330863,NO,135,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-1.331,-2.136,0.805,,0.071,.,a,0.17,0.65,3.574,,53.03,ABP,-1.77367,0.520039,0.00532566,0.330863 kka2_1:1_V36E,kka2_1:1_36,Kka2,kka2_1:1,P00552,0.330867,NO,36,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-0.898,-3.776,2.878,,0.292,E,B,0.44,0.21,0.278,,52.27,HHH,-1.484,0.520039,0.00245633,0.330867 Pab1_K131T,Pab1_131,Pab1,Pab1,P04147,0.330883,NO,131,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.083,-3.239,2.156,,0.462,E,B,1.82,0.57,,,,HBP,-1.12467,0.175299,0.000349395,0.330883 kka2_1:1_V16I,kka2_1:1_16,Kka2,kka2_1:1,P00552,0.330905,NO,16,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-3.087,-3.948,0.861,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.520039,0.00694011,0.330905 beta-lactamase_F14K,beta-lactamase_14,TEM-1,beta-lactamase,P62593,0.330915,NO,14,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-2.736,-3.752,1.016,,,,,,,1.537,,93.01,HHH,-2.26133,0.221079,0.00277095,0.330915 beta-lactamase_V257W,beta-lactamase_257,TEM-1,beta-lactamase,P62593,0.330915,NO,257,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.533,-5.405,3.872,5.31999,,E,B,0.96,-0.7,1.463,,58.74,HHH,-1.70967,0.221079,0.00756629,0.330915 beta-lactamase_2500_S51W,beta-lactamase_2500_51,TEM-1,beta-lactamase_2500,P62593,0.330943,NO,51,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.526,-5.435,3.909,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.361275,0.00504821,0.330943 kka2_1:2_F264P,kka2_1:2_264,Kka2,kka2_1:2,P00552,0.330952,NO,264,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.02,-4.363,3.343,,0.296,.,?,0.58,0.02,2.303,,71.59,HHNA,-0.9655,0.295029,,0.330952 kka2_1:4_A191R,kka2_1:4_191,Kka2,kka2_1:4,P00552,0.330979,NO,191,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.831,-3.8,2.969,,,.,b,0.46,-0.94,2.046,,50,AHO,-0.868667,0.168804,0.00338807,0.330979 beta-lactamase_W227C,beta-lactamase_227,TEM-1,beta-lactamase,P62593,0.331001,NO,227,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-0.982,-4.932,3.95,4.86393,0.272,,B,0.99,-0.29,1.37,,74.48,OHH,-1.595,0.221079,0.00226019,0.331001 beta-lactamase_156_R159P,beta-lactamase_156_159,TEM-1,beta-lactamase_156,P62593,0.331009,NO,159,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-0.94,-3.905,2.965,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.111618,0.00108472,0.331009 kka2_1:2_D156M,kka2_1:2_156,Kka2,kka2_1:2,P00552,0.331014,NO,156,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.696,-4.858,3.162,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.295029,0.00926998,0.331014 beta-lactamase_2500_P224Y,beta-lactamase_2500_224,TEM-1,beta-lactamase_2500,P62593,0.33103,NO,224,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.893,-4.387,3.494,,0.383,,B,0.52,-0.3,2.666,,74.48,HOH,-1.26433,0.361275,0.00189564,0.33103 kka2_1:1_L94D,kka2_1:1_94,Kka2,kka2_1:1,P00552,0.331039,NO,94,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.618,-4.088,2.47,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.520039,0.00520888,0.331039 kka2_1:8_D208P,kka2_1:8_208,Kka2,kka2_1:8,P00552,0.33121,NO,208,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.708,-3.683,2.975,,0.36,,l,0.29,-1.01,,,,HAO,-0.929667,0.100394,0.00212588,0.33121 kka2_1:8_D208P,kka2_1:8_208,Kka2,kka2_1:8,P00552,0.33121,NO,208,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.708,-3.683,2.975,,0.36,,l,0.29,-1.01,,,,HAO,-0.929667,0.100394,0.00212588,0.33121 kka2_1:4_I207G,kka2_1:4_207,Kka2,kka2_1:4,P00552,0.331243,NO,207,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.175,-3.853,2.678,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.168804,0.00611824,0.331243 kka2_1:8_A117M,kka2_1:8_117,Kka2,kka2_1:8,P00552,0.331336,NO,117,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.828,-4.464,3.636,,,H,A,1.04,-0.78,0.755,,45.83,HHA,-1.79333,0.100394,0.00282984,0.331336 kka2_1:8_A117M,kka2_1:8_117,Kka2,kka2_1:8,P00552,0.331336,NO,117,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.828,-4.464,3.636,,,H,A,1.04,-0.78,0.755,,45.83,HHA,-1.79333,0.100394,0.00282984,0.331336 kka2_1:2_N200W,kka2_1:2_200,Kka2,kka2_1:2,P00552,0.33135,NO,200,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-2.446,-5.597,3.151,,0.756,T,L,0.61,-0.08,2.836,,64.39,APO,-2.08,0.295029,0.00838549,0.33135 beta-lactamase_156_N134E,beta-lactamase_156_134,TEM-1,beta-lactamase_156,P62593,0.331377,NO,134,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-0.879,-3.212,2.333,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.111618,0.000644786,0.331377 kka2_1:2_L193K,kka2_1:2_193,Kka2,kka2_1:2,P00552,0.33142,NO,193,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.983,-3.668,2.685,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.295029,0.00480179,0.33142 kka2_1:1_W69M,kka2_1:1_69,Kka2,kka2_1:1,P00552,0.331634,NO,69,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-0.859,-4.531,3.672,,0.164,H,A,0.47,0.15,5.074,,38.64,PHH,-1.49967,0.520039,0.0012874,0.331634 kka2_1:4_C192P,kka2_1:4_192,Kka2,kka2_1:4,P00552,0.33169,NO,192,C,P,CP,Special,Special,5.07,6.3,1.23,169,121,115,-6,108.5,112.7,4.2,-1.067,-4.099,3.032,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.168804,0.00485428,0.33169 beta-lactamase_2500_L146G,beta-lactamase_2500_146,TEM-1,beta-lactamase_2500,P62593,0.331713,NO,146,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.462,-3.742,2.28,,0.007,H,A,0.55,-0.56,1.578,,64.69,AHP,-1.656,0.361275,0.00474542,0.331713 kka2_1:1_E142T,kka2_1:1_142,Kka2,kka2_1:1,P00552,0.331723,NO,142,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.221,-2.837,0.616,,0.471,H,A,1.52,0.85,3.626,,65.53,HAB,-2.08033,0.520039,0.00748883,0.331723 beta-lactamase_2500_P165F,beta-lactamase_2500_165,TEM-1,beta-lactamase_2500,P62593,0.331747,NO,165,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.373,-4.322,2.949,,0.203,T,A,0.52,-0.31,0.414,,73.78,AOA,-1.359,0.361275,0.00549538,0.331747 kka2_1:1_L259V,kka2_1:1_259,Kka2,kka2_1:1,P00552,0.331766,NO,259,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.088,-2.47,1.382,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.520039,0.0206964,0.331766 kka2_1:1_E231T,kka2_1:1_231,Kka2,kka2_1:1,P00552,0.331829,NO,231,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.002,-3.44,1.438,,0.503,H,A,1.04,-0.23,25.629,25.629,63.26,AAH,-2.06267,0.520039,0.00732383,0.331829 kka2_1:8_E262A,kka2_1:8_262,Kka2,kka2_1:8,P00552,0.33184,NO,262,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-0.829,-3.129,2.3,,0.059,G,A,1.52,-0.18,0.837,,42.42,AAH,-0.816,0.100394,0.0191586,0.33184 kka2_1:8_E262A,kka2_1:8_262,Kka2,kka2_1:8,P00552,0.33184,NO,262,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-0.829,-3.129,2.3,,0.059,G,A,1.52,-0.18,0.837,,42.42,AAH,-0.816,0.100394,0.0191586,0.33184 kka2_1:1_R147I,kka2_1:1_147,Kka2,kka2_1:1,P00552,0.331911,NO,147,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.123,-4.139,3.016,,0.094,H,A,1.2,0.97,2.578,,64.02,PBH,-1.98267,0.520039,0.00549168,0.331911 kka2_1:1_D208H,kka2_1:1_208,Kka2,kka2_1:1,P00552,0.331925,NO,208,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.708,-4.483,3.775,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.520039,0.00212588,0.331925 kka2_1:1_Q27F,kka2_1:1_27,Kka2,kka2_1:1,P00552,0.332089,NO,27,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-1.659,-4.291,2.632,,0.608,.,A,0.64,0.71,0.521,,65.53,PPP,-1.90733,0.520039,0.00595365,0.332089 kka2_1:4_L67S,kka2_1:4_67,Kka2,kka2_1:4,P00552,0.332101,NO,67,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.741,-3.639,2.898,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.168804,0.00102787,0.332101 beta-lactamase_2500_L150N,beta-lactamase_2500_150,TEM-1,beta-lactamase_2500,P62593,0.332103,NO,150,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.326,-4.088,2.762,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.361275,0.00463171,0.332103 kka2_1:4_D208N,kka2_1:4_208,Kka2,kka2_1:4,P00552,0.332169,NO,208,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.708,-3.251,2.543,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.168804,0.00212588,0.332169 beta-lactamase_2500_R257Y,beta-lactamase_2500_257,TEM-1,beta-lactamase_2500,P62593,0.332175,NO,257,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.361275,0.00756629,0.332175 kka2_1:2_T72F,kka2_1:2_72,Kka2,kka2_1:2,P00552,0.332177,NO,72,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.38,-4.46,2.08,,0.784,H,A,0.82,0.29,6.463,,65.53,HPP,-2.238,0.295029,0.00750756,0.332177 kka2_1:1_Y257E,kka2_1:1_257,Kka2,kka2_1:1,P00552,0.332195,NO,257,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-1.064,-3.82,2.756,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.520039,0.0148191,0.332195 kka2_1:1_L165G,kka2_1:1_165,Kka2,kka2_1:1,P00552,0.332208,NO,165,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-2.453,-3.006,0.553,,0.299,,B,1.59,1.12,2.47,,64.39,OHH,-1.90967,0.520039,0.00801161,0.332208 kka2_1:1_L259A,kka2_1:1_259,Kka2,kka2_1:1,P00552,0.332239,NO,259,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.088,-2.512,1.424,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.520039,0.0206964,0.332239 beta-lactamase_2500_L160G,beta-lactamase_2500_160,TEM-1,beta-lactamase_2500,P62593,0.332259,NO,160,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.977,-3.824,2.847,,0.022,,B,0.55,-0.6,0.895,,44.41,BHA,-0.936,0.361275,0.00193775,0.332259 kka2_1:1_M120K,kka2_1:1_120,Kka2,kka2_1:1,P00552,0.332266,NO,120,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-3.877,-3.733,-0.144,,,H,A,0.55,-0.42,2.259,,92.05,HHB,-2.16733,0.520039,0.00265808,0.332266 kka2_1:1_R202T,kka2_1:1_202,Kka2,kka2_1:1,P00552,0.33237,NO,202,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.761,-3.676,1.915,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.520039,0.00696498,0.33237 kka2_1:1_A110Y,kka2_1:1_110,Kka2,kka2_1:1,P00552,0.332387,NO,110,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.064,-4.356,2.292,,0.175,H,A,1.04,-1.19,11.755,,71.59,OHA,-1.91867,0.520039,0.00759851,0.332387 beta-lactamase_625_D161F,beta-lactamase_625_161,TEM-1,beta-lactamase_625,P62593,0.332487,NO,161,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.891,-4.316,3.425,,0.341,,A,0.75,-0.52,4.655,,61.19,HAB,-0.961333,0.213352,0.000897697,0.332487 kka2_1:1_L70Q,kka2_1:1_70,Kka2,kka2_1:1,P00552,0.33249,NO,70,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.017,-4.149,3.132,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.520039,0.00411884,0.33249 beta-lactamase_2500_P250F,beta-lactamase_2500_250,TEM-1,beta-lactamase_2500,P62593,0.332525,NO,250,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.361275,0.00550899,0.332525 kka2_1:2_R173P,kka2_1:2_173,Kka2,kka2_1:2,P00552,0.332603,NO,173,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.407,-4.037,1.63,,0.308,H,A,0.16,-0.13,15.389,15.389,65.53,HBH,-1.70533,0.295029,0.00784999,0.332603 beta-lactamase_156_G236L,beta-lactamase_156_236,TEM-1,beta-lactamase_156,P62593,0.332609,NO,236,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.784,-3.712,2.928,,0.241,,b,0.29,-0.59,1.883,,64.69,HOO,-1.025,0.111618,0.00162372,0.332609 kka2_1:1_E182N,kka2_1:1_182,Kka2,kka2_1:1,P00552,0.33264,NO,182,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.516,-3.686,2.17,,0.326,,B,1.52,0.75,14.547,14.547,65.53,OAA,-1.806,0.520039,0.00641548,0.33264 kka2_1:1_G151Q,kka2_1:1_151,Kka2,kka2_1:1,P00552,0.332675,NO,151,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.873,-4.048,3.175,,0.678,T,l,0.29,1.36,0.226,,49.62,HOH,-1.11433,0.520039,0.00339918,0.332675 Pab1_N127I,Pab1_127,Pab1,Pab1,P04147,0.332728,NO,127,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-1.079,-3.827,2.748,,0.138,E,B,1.05,-0.51,,,,OPH,-1.13633,0.175299,0.000805159,0.332728 beta-lactamase_39_D177Q,beta-lactamase_39_177,TEM-1,beta-lactamase_39,P62593,0.332825,NO,177,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.967,-3.799,2.832,,0.006,T,L,0.75,-1.02,3.536,,64.69,BAP,-0.873667,0.0495842,0.000864022,0.332825 kka2_1:4_G205E,kka2_1:4_205,Kka2,kka2_1:4,P00552,0.332873,NO,205,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.596,-3.693,3.097,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.168804,0.00221855,0.332873 beta-lactamase_2500_P181S,beta-lactamase_2500_181,TEM-1,beta-lactamase_2500,P62593,0.332904,NO,181,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.813,-3.349,2.536,,,H,A,0.52,-1.14,1.946,,61.54,HOH,-1.795,0.361275,0.000703122,0.332904 beta-lactamase_625_V42S,beta-lactamase_625_42,TEM-1,beta-lactamase_625,P62593,0.332906,NO,42,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.564,-3.633,2.069,,0.017,E,B,0.44,-0.51,2.576,,63.99,BHO,-1.042,0.213352,0.00404515,0.332906 beta-lactamase_156_V72W,beta-lactamase_156_72,TEM-1,beta-lactamase_156,P62593,0.332915,NO,72,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.658,-3.279,1.621,,,H,A,0.44,-1.03,1.92,,65.73,BHH,-1.32167,0.111618,0.00501194,0.332915 kka2_1:8_K50H,kka2_1:8_50,Kka2,kka2_1:8,P00552,0.333095,NO,50,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-0.833,-4.481,3.648,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.100394,0.00138626,0.333095 kka2_1:8_K50H,kka2_1:8_50,Kka2,kka2_1:8,P00552,0.333095,NO,50,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-0.833,-4.481,3.648,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.100394,0.00138626,0.333095 beta-lactamase_625_R220P,beta-lactamase_625_220,TEM-1,beta-lactamase_625,P62593,0.333121,NO,220,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-0.942,-3.877,2.935,,0.295,I,A,1.2,-0.76,5.086,,74.48,HBP,-1.33633,0.213352,0.00232421,0.333121 beta-lactamase_2500_L197W,beta-lactamase_2500_197,TEM-1,beta-lactamase_2500,P62593,0.333186,NO,197,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.853,-5.146,4.293,,0.007,S,B,0.55,0.33,2.421,,60.14,HHP,-1.833,0.361275,0.00144602,0.333186 kka2_1:2_G30T,kka2_1:2_30,Kka2,kka2_1:2,P00552,0.333199,NO,30,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.596,-3.675,3.079,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.295029,0.00159208,0.333199 beta-lactamase_M209S,beta-lactamase_209,TEM-1,beta-lactamase,P62593,0.333206,NO,209,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.442,-3.579,2.137,5.44502,,H,A,1.75,-0.97,1.402,,64.69,HHA,-1.52633,0.221079,0.00625021,0.333206 kka2_1:1_P179I,kka2_1:1_179,Kka2,kka2_1:1,P00552,0.33332,NO,179,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.974,-3.795,2.821,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.520039,0.00298346,0.33332 kka2_1:1_Y257L,kka2_1:1_257,Kka2,kka2_1:1,P00552,0.333322,NO,257,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-1.064,-3.141,2.077,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.520039,0.0148191,0.333322 kka2_1:4_V75R,kka2_1:4_75,Kka2,kka2_1:4,P00552,0.333375,NO,75,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-2.06,-4.101,2.041,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.168804,0.00693733,0.333375 kka2_1:2_R145I,kka2_1:2_145,Kka2,kka2_1:2,P00552,0.333378,NO,145,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.804,-4.111,2.307,,0.346,H,A,1.2,1.23,7.961,,63.64,HBP,-1.88033,0.295029,0.00846663,0.333378 kka2_1:1_L193F,kka2_1:1_193,Kka2,kka2_1:1,P00552,0.333435,NO,193,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.983,-3.816,2.833,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.520039,0.00480179,0.333435 hsp90_M589S,hsp90_589,hsp90,hsp90,P02829,0.333438,NO,589,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-3.858,-2.764,0,4.72723,0.032,H,A,0.84,0.31,,,,PHA,-3.24233,0.368192,0.000222939,0.333438 beta-lactamase_39_A133D,beta-lactamase_39_133,TEM-1,beta-lactamase_39,P62593,0.333611,NO,133,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.186,-3.675,2.489,,,H,A,0.46,-0.86,0.373,,67.83,HHP,-0.988333,0.0495842,0.00468022,0.333611 beta-lactamase_625_R189P,beta-lactamase_625_189,TEM-1,beta-lactamase_625,P62593,0.333639,NO,189,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.844,-3.964,2.12,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.213352,0.0050699,0.333639 beta-lactamase_625_A40R,beta-lactamase_625_40,TEM-1,beta-lactamase_625,P62593,0.333812,NO,40,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.402,-3.924,2.522,,0.155,S,B,0.46,0.21,1.357,,73.78,OHB,-1.40267,0.213352,0.00490026,0.333812 kka2_1:4_R217P,kka2_1:4_217,Kka2,kka2_1:4,P00552,0.33396,NO,217,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.158,-2.617,1.459,,0.252,T,A,1.2,-0.59,2.074,,52.27,ABH,-1.127,0.168804,0.0047191,0.33396 beta-lactamase_I125F,beta-lactamase_125,TEM-1,beta-lactamase,P62593,0.334034,NO,125,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.441,-3.841,2.4,5.23481,,H,A,2.82,-0.7,2.301,,63.29,HHP,-1.248,0.221079,0.00383964,0.334034 beta-lactamase_V101P,beta-lactamase_101,TEM-1,beta-lactamase,P62593,0.334034,NO,101,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.295,-4.04,2.745,5.49045,0.342,,B,0.96,0,1.675,,73.08,HHA,-1.54367,0.221079,0.00374492,0.334034 kka2_1:1_R258C,kka2_1:1_258,Kka2,kka2_1:1,P00552,0.334062,NO,258,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.626,-2.089,0.463,,0.316,H,A,1.2,-0.85,7.485,7.485,53.03,HBH,-1.25933,0.520039,0.00983174,0.334062 kka2_1:1_E161T,kka2_1:1_161,Kka2,kka2_1:1,P00552,0.334076,NO,161,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.581,-2.315,0.734,,0.829,G,A,1.04,2.24,1.612,,92.05,AAB,-1.861,0.520039,0.00760103,0.334076 kka2_1:1_F263H,kka2_1:1_263,Kka2,kka2_1:1,P00552,0.334119,NO,263,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-0.911,-4.571,3.66,,0.006,G,A,0.58,-0.12,2.284,,45.83,AHH,-0.92,0.520039,0.0172454,0.334119 beta-lactamase_2500_I285K,beta-lactamase_2500_285,TEM-1,beta-lactamase_2500,P62593,0.334123,NO,285,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.361275,0.101555,0.334123 kka2_1:4_G205L,kka2_1:4_205,Kka2,kka2_1:4,P00552,0.334175,NO,205,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.596,-3.836,3.24,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.168804,0.00221855,0.334175 beta-lactamase_156_N130V,beta-lactamase_156_130,TEM-1,beta-lactamase_156,P62593,0.33425,NO,130,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-0.798,-3.754,2.956,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.111618,0.000683376,0.33425 beta-lactamase_39_A230K,beta-lactamase_39_230,TEM-1,beta-lactamase_39,P62593,0.334319,NO,230,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.154,-3.583,2.429,,0.01,E,B,0.46,-1.17,1.171,,50,HHA,-1.079,0.0495842,0.00516841,0.334319 kka2_1:1_K50D,kka2_1:1_50,Kka2,kka2_1:1,P00552,0.334323,NO,50,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-0.833,-3.541,2.708,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.520039,0.00138626,0.334323 kka2_1:1_V153G,kka2_1:1_153,Kka2,kka2_1:1,P00552,0.334343,NO,153,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.092,-3.674,2.582,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.520039,0.00501119,0.334343 beta-lactamase_156_V117D,beta-lactamase_156_117,TEM-1,beta-lactamase_156,P62593,0.334377,NO,117,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.53,-4.116,2.586,,,H,A,0.44,-0.34,1.182,,65.03,PHB,-1.741,0.111618,0.00467906,0.334377 kka2_1:1_V198G,kka2_1:1_198,Kka2,kka2_1:1,P00552,0.334424,NO,198,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.719,-3.368,1.649,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.520039,0.00835002,0.334424 beta-lactamase_625_G226I,beta-lactamase_625_226,TEM-1,beta-lactamase_625,P62593,0.334491,NO,226,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.461,-4.177,2.716,,0.701,T,l,0.29,-0.25,3.199,,74.48,HOH,-1.42933,0.213352,0.00665294,0.334491 kka2_1:1_V186M,kka2_1:1_186,Kka2,kka2_1:1,P00552,0.334514,NO,186,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.011,-4.138,3.127,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.520039,0.00409703,0.334514 kka2_1:2_L107C,kka2_1:2_107,Kka2,kka2_1:2,P00552,0.334535,NO,107,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.238,-4.827,3.589,,0.197,,B,1.59,-1.1,2.68,,71.59,BHH,-2.143,0.295029,0.00561937,0.334535 kka2_1:1_W15D,kka2_1:1_15,Kka2,kka2_1:1,P00552,0.33454,NO,15,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-1.392,-4.212,2.82,,0.01,G,A,0.47,0.15,20.149,20.149,52.27,HHH,-2.10533,0.520039,0.00585505,0.33454 kka2_1:1_L92H,kka2_1:1_92,Kka2,kka2_1:1,P00552,0.334557,NO,92,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.893,-4.966,4.073,,0.007,E,B,0.55,-0.19,1.447,,63.26,HHH,-0.962,0.520039,0.00307177,0.334557 beta-lactamase_156_G249F,beta-lactamase_156_249,TEM-1,beta-lactamase_156,P62593,0.334582,NO,249,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.111618,0.00220169,0.334582 kka2_1:1_L92R,kka2_1:1_92,Kka2,kka2_1:1,P00552,0.334597,NO,92,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.893,-4.021,3.128,,0.007,E,B,0.55,-0.19,1.447,,63.26,HHH,-0.962,0.520039,0.00307177,0.334597 kka2_1:1_R239V,kka2_1:1_239,Kka2,kka2_1:1,P00552,0.334598,NO,239,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.949,-2.967,0.018,,0.15,H,A,1.2,-0.31,0.477,,71.59,ABH,-2.23,0.520039,0.00835326,0.334598 gb1_N261H,gb1_261,gb1,gb1,P06654,0.334605,NO,261,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-1.863,-4.228,2.365,,,,,,,1.191,,44.87,HPA,-2.16033,0.177985,0.0061875,0.334605 kka2_1:1_A41H,kka2_1:1_41,Kka2,kka2_1:1,P00552,0.334648,NO,41,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.879,-3.045,1.166,,0.184,.,B,0.46,-0.96,18.207,18.207,64.39,PHP,-2.477,0.520039,0.00543332,0.334648 beta-lactamase_625_L218Y,beta-lactamase_625_218,TEM-1,beta-lactamase_625,P62593,0.3347,NO,218,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.391,-4.087,2.696,,,I,b,0.55,-0.53,17.202,17.202,74.48,OHH,-1.58867,0.213352,0.00618274,0.3347 kka2_1:8_L193H,kka2_1:8_193,Kka2,kka2_1:8,P00552,0.334719,NO,193,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.983,-4.891,3.908,,,G,A,1.59,-1.03,2.234,,65.53,OHO,-0.965333,0.100394,0.00480179,0.334719 kka2_1:8_L193H,kka2_1:8_193,Kka2,kka2_1:8,P00552,0.334719,NO,193,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.983,-4.891,3.908,,,G,A,1.59,-1.03,2.234,,65.53,OHO,-0.965333,0.100394,0.00480179,0.334719 beta-lactamase_2500_I285G,beta-lactamase_2500_285,TEM-1,beta-lactamase_2500,P62593,0.33475,NO,285,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.361275,0.101555,0.33475 beta-lactamase_D212L,beta-lactamase_212,TEM-1,beta-lactamase,P62593,0.334786,NO,212,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.624,-3.598,1.974,4.9705,0.037,,b,1.3,-0.58,12.482,,74.48,HAB,-1.77667,0.221079,0.00644302,0.334786 beta-lactamase_39_L146R,beta-lactamase_39_146,TEM-1,beta-lactamase_39,P62593,0.334859,NO,146,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.462,-4.192,2.73,,0.007,H,A,0.55,-0.56,1.953,,64.69,AHP,-1.656,0.0495842,0.00474542,0.334859 beta-lactamase_625_L49D,beta-lactamase_625_49,TEM-1,beta-lactamase_625,P62593,0.334883,NO,49,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.897,-3.778,1.881,,0.131,T,A,0.55,0.04,3.112,,64.69,AHP,-1.99233,0.213352,0.00401477,0.334883 Pab1_I137D,Pab1_137,Pab1,Pab1,P04147,0.334896,NO,137,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.212,-3.736,2.524,,0.068,,B,0.77,0.35,,,,AHA,-1.314,0.175299,0.000342224,0.334896 beta-lactamase_625_L205C,beta-lactamase_625_205,TEM-1,beta-lactamase_625,P62593,0.334898,NO,205,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.922,-4.692,3.77,,,H,A,0.55,-0.46,3.782,,42.31,PHH,-1.57767,0.213352,0.00255802,0.334898 kka2_1:4_L232R,kka2_1:4_232,Kka2,kka2_1:4,P00552,0.334924,NO,232,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.514,-4.216,2.702,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.168804,0.00800103,0.334924 beta-lactamase_625_R63D,beta-lactamase_625_63,TEM-1,beta-lactamase_625,P62593,0.334952,NO,63,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-0.943,-3.762,2.819,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.213352,0.00126938,0.334952 kka2_1:2_A215N,kka2_1:2_215,Kka2,kka2_1:2,P00552,0.334965,NO,215,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.968,-3.769,2.801,,0.039,E,B,0.46,-0.59,2.137,,50.38,HHA,-1.00467,0.295029,0.00529129,0.334965 kka2_1:8_G210K,kka2_1:8_210,Kka2,kka2_1:8,P00552,0.334968,NO,210,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.095,-3.696,2.601,,0.103,T,A,0.75,-0.62,2.687,,50,OOB,-0.966667,0.100394,0.00598378,0.334968 kka2_1:8_G210K,kka2_1:8_210,Kka2,kka2_1:8,P00552,0.334968,NO,210,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.095,-3.696,2.601,,0.103,T,A,0.75,-0.62,2.687,,50,OOB,-0.966667,0.100394,0.00598378,0.334968 kka2_1:4_F256H,kka2_1:4_256,Kka2,kka2_1:4,P00552,0.335101,NO,256,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.49,-4.32,2.83,,,H,A,0.58,-0.78,1.653,,53.03,HHH,-1.423,0.168804,0.0132841,0.335101 beta-lactamase_625_D161G,beta-lactamase_625_161,TEM-1,beta-lactamase_625,P62593,0.335124,NO,161,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.891,-3.177,2.286,,0.341,,A,0.75,-0.52,4.655,,61.19,HAB,-0.961333,0.213352,0.000897697,0.335124 kka2_1:1_F264T,kka2_1:1_264,Kka2,kka2_1:1,P00552,0.335145,NO,264,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.02,-3.729,2.709,,0.296,.,?,0.58,0.02,2.303,,71.59,HHNA,-0.9655,0.520039,,0.335145 kka2_1:2_F256H,kka2_1:2_256,Kka2,kka2_1:2,P00552,0.335147,NO,256,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.49,-4.32,2.83,,,H,A,0.58,-0.78,1.653,,53.03,HHH,-1.423,0.295029,0.0132841,0.335147 kka2_1:2_L232Q,kka2_1:2_232,Kka2,kka2_1:2,P00552,0.335175,NO,232,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.514,-4.349,2.835,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.295029,0.00800103,0.335175 beta-lactamase_G239F,beta-lactamase_239,TEM-1,beta-lactamase,P62593,0.335192,NO,239,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.819,-4.295,3.476,4.85529,0.115,T,l,0.77,-0.62,1.817,,42.31,BOP,-1.45267,0.221079,0.00213852,0.335192 kka2_1:2_S32F,kka2_1:2_32,Kka2,kka2_1:2,P00552,0.335214,NO,32,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-0.804,-4.095,3.291,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.295029,0.00149998,0.335214 beta-lactamase_39_L192P,beta-lactamase_39_192,TEM-1,beta-lactamase_39,P62593,0.335223,NO,192,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.254,-4.129,2.875,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.0495842,0.00558728,0.335223 beta-lactamase_2500_P143E,beta-lactamase_2500_143,TEM-1,beta-lactamase_2500,P62593,0.33529,NO,143,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.967,-3.58,2.613,,0.075,H,A,0.52,-0.37,0.479,,66.78,OOB,-1.354,0.361275,0.00114551,0.33529 kka2_1:2_H188M,kka2_1:2_188,Kka2,kka2_1:2,P00552,0.335319,NO,188,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-0.913,-4.701,3.788,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.295029,0.00273139,0.335319 kka2_1:4_E182N,kka2_1:4_182,Kka2,kka2_1:4,P00552,0.335341,NO,182,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.516,-3.686,2.17,,0.326,.,B,1.04,0.75,4.755,,65.53,OAA,-1.806,0.168804,0.00641548,0.335341 kka2_1:1_V153C,kka2_1:1_153,Kka2,kka2_1:1,P00552,0.335342,NO,153,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.092,-4.724,3.632,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.520039,0.00501119,0.335342 beta-lactamase_2500_A123Y,beta-lactamase_2500_123,TEM-1,beta-lactamase_2500,P62593,0.335502,NO,123,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.834,-4.16,3.326,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.361275,0.0010157,0.335502 kka2_1:1_A108D,kka2_1:1_108,Kka2,kka2_1:1,P00552,0.33553,NO,108,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.061,-2.378,0.317,,0.243,.,B,0.46,-1.34,3.156,,71.59,HHO,-1.57033,0.520039,0.00751209,0.33553 beta-lactamase_2500_W288L,beta-lactamase_2500_288,TEM-1,beta-lactamase_2500,P62593,0.335674,NO,288,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,,,,,,,,,,,,,BHO,,0.361275,,0.335674 kka2_1:4_D159W,kka2_1:4_159,Kka2,kka2_1:4,P00552,0.335748,NO,159,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.82,-5.531,4.711,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.168804,0.0030485,0.335748 kka2_1:1_L92V,kka2_1:1_92,Kka2,kka2_1:1,P00552,0.335755,NO,92,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.893,-2.208,1.315,,0.007,E,B,0.55,-0.19,1.447,,63.26,HHH,-0.962,0.520039,0.00307177,0.335755 beta-lactamase_2500_I245S,beta-lactamase_2500_245,TEM-1,beta-lactamase_2500,P62593,0.335778,NO,245,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.361275,0.00391032,0.335778 kka2_1:2_P179G,kka2_1:2_179,Kka2,kka2_1:2,P00552,0.3358,NO,179,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.974,-3.438,2.464,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.295029,0.00298346,0.3358 beta-lactamase_625_T131K,beta-lactamase_625_131,TEM-1,beta-lactamase_625,P62593,0.335828,NO,131,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.328,-3.481,2.153,,,H,A,0.22,-0.69,2.031,,67.48,PPH,-1.00867,0.213352,0.00345886,0.335828 kka2_1:8_V214H,kka2_1:8_214,Kka2,kka2_1:8,P00552,0.335839,NO,214,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.261,-5.011,3.75,,0.117,E,B,1.48,-0.31,1.859,,64.39,OHH,-0.941667,0.100394,0.00692782,0.335839 kka2_1:8_V214H,kka2_1:8_214,Kka2,kka2_1:8,P00552,0.335839,NO,214,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.261,-5.011,3.75,,0.117,E,B,1.48,-0.31,1.859,,64.39,OHH,-0.941667,0.100394,0.00692782,0.335839 kka2_1:4_A191I,kka2_1:4_191,Kka2,kka2_1:4,P00552,0.335878,NO,191,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.831,-3.676,2.845,,,.,b,0.46,-0.94,2.046,,50,AHO,-0.868667,0.168804,0.00338807,0.335878 beta-lactamase_156_G234Y,beta-lactamase_156_234,TEM-1,beta-lactamase_156,P62593,0.335954,NO,234,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.62,-4.387,3.767,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.111618,0.000889577,0.335954 kka2_1:8_P194I,kka2_1:8_194,Kka2,kka2_1:8,P00552,0.335963,NO,194,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.846,-4.06,3.214,,0.308,G,A,0.52,-1.19,4.861,,53.03,HOP,-0.888333,0.100394,0.00314194,0.335963 kka2_1:8_P194I,kka2_1:8_194,Kka2,kka2_1:8,P00552,0.335963,NO,194,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.846,-4.06,3.214,,0.308,G,A,0.52,-1.19,4.861,,53.03,HOP,-0.888333,0.100394,0.00314194,0.335963 beta-lactamase_G236M,beta-lactamase_236,TEM-1,beta-lactamase,P62593,0.335988,NO,236,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.784,-4.869,4.085,4.7915,0.241,,b,0.23,-0.59,1.883,,64.69,HOA,-1.36933,0.221079,0.00162372,0.335988 kka2_1:2_I221D,kka2_1:2_221,Kka2,kka2_1:2,P00552,0.336038,NO,221,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.739,-4.188,2.449,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.295029,0.00945908,0.336038 beta-lactamase_2500_G52F,beta-lactamase_2500_52,TEM-1,beta-lactamase_2500,P62593,0.336056,NO,52,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.149,-4.393,3.244,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.361275,0.00340138,0.336056 kka2_1:4_F264V,kka2_1:4_264,Kka2,kka2_1:4,P00552,0.336074,NO,264,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.02,-3.361,2.341,,0.296,,?,1.62,0.02,1.93,,71.59,HHO,-0.9655,0.168804,,0.336074 kka2_1:1_A247W,kka2_1:1_247,Kka2,kka2_1:1,P00552,0.336084,NO,247,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.459,-5.465,3.006,,1.01,S,A,0.46,0.65,7.731,7.731,92.05,HHH,-2.197,0.520039,0.0102428,0.336084 kka2_1:8_H188E,kka2_1:8_188,Kka2,kka2_1:8,P00552,0.336087,NO,188,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-0.913,-3.211,2.298,,0.006,,A,0.87,-1.02,1.241,,47.73,PBO,-0.927333,0.100394,0.00273139,0.336087 kka2_1:8_H188E,kka2_1:8_188,Kka2,kka2_1:8,P00552,0.336087,NO,188,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-0.913,-3.211,2.298,,0.006,,A,0.87,-1.02,1.241,,47.73,PBO,-0.927333,0.100394,0.00273139,0.336087 beta-lactamase_2500_L218T,beta-lactamase_2500_218,TEM-1,beta-lactamase_2500,P62593,0.336222,NO,218,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.391,-2.536,1.145,,,I,b,0.55,-0.53,9.151,9.151,74.48,OHH,-1.58867,0.361275,0.00618274,0.336222 kka2_1:1_H8T,kka2_1:1_8,Kka2,kka2_1:1,P00552,0.336238,NO,8,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-2.759,-3.343,0.584,,,,,,,16.971,16.971,71.59,HBH,-2.25467,0.520039,0.00256422,0.336238 kka2_1:2_F203N,kka2_1:2_203,Kka2,kka2_1:2,P00552,0.33632,NO,203,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-0.911,-4.185,3.274,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.295029,0.00318738,0.33632 kka2_1:1_Q136G,kka2_1:1_136,Kka2,kka2_1:1,P00552,0.336333,NO,136,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-3.021,-2.521,-0.5,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.520039,0.00624149,0.336333 kka2_1:1_Q252G,kka2_1:1_252,Kka2,kka2_1:1,P00552,0.336411,NO,252,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.63,-2.545,-0.085,,0.906,H,A,0.64,0.35,1.369,,92.05,PPB,-2.20733,0.520039,0.0121001,0.336411 kka2_1:1_A137N,kka2_1:1_137,Kka2,kka2_1:1,P00552,0.336449,NO,137,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.156,-4.15,1.994,,0.029,H,A,0.46,0.34,1.323,,63.26,PHB,-2.559,0.520039,0.00515054,0.336449 beta-lactamase_2500_G141Y,beta-lactamase_2500_141,TEM-1,beta-lactamase_2500,P62593,0.336467,NO,141,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.828,-4.424,3.596,,0.575,T,l,0.29,-0.28,1.493,,64.69,HOO,-1.08933,0.361275,0.0012419,0.336467 kka2_1:4_Y22E,kka2_1:4_22,Kka2,kka2_1:4,P00552,0.336549,NO,22,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-1.583,-3.743,2.16,,0.122,.,B,0.21,-0.8,1.838,,65.53,OHA,-1.80333,0.168804,0.00598977,0.336549 beta-lactamase_39_L167W,beta-lactamase_39_167,TEM-1,beta-lactamase_39,P62593,0.336581,NO,167,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.138,-5.22,4.082,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.0495842,0.00303566,0.336581 kka2_1:8_D261N,kka2_1:8_261,Kka2,kka2_1:8,P00552,0.336583,NO,261,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.708,-3.251,2.543,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.100394,0.0224846,0.336583 kka2_1:8_D261N,kka2_1:8_261,Kka2,kka2_1:8,P00552,0.336583,NO,261,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.708,-3.251,2.543,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.100394,0.0224846,0.336583 kka2_1:1_G21F,kka2_1:1_21,Kka2,kka2_1:1,P00552,0.336587,NO,21,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.368,-4.373,3.005,,0.586,T,l,0.29,-0.75,10.291,10.291,71.59,HOH,-2.10167,0.520039,0.00709648,0.336587 kka2_1:2_R202F,kka2_1:2_202,Kka2,kka2_1:2,P00552,0.336593,NO,202,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.761,-4.435,2.674,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.295029,0.00696498,0.336593 kka2_1:8_M148Y,kka2_1:8_148,Kka2,kka2_1:8,P00552,0.336707,NO,148,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.847,-4.225,2.378,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.100394,0.00982664,0.336707 kka2_1:8_M148Y,kka2_1:8_148,Kka2,kka2_1:8,P00552,0.336707,NO,148,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.847,-4.225,2.378,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.100394,0.00982664,0.336707 beta-lactamase_0_V117F,beta-lactamase_0_117,TEM-1,beta-lactamase_0,P62593,0.336741,NO,117,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.53,-3.756,2.226,,,H,A,0.44,-0.34,1.16,,65.03,PHB,-1.741,0.0500837,0.00467906,0.336741 kka2_1:8_W236K,kka2_1:8_236,Kka2,kka2_1:8,P00552,0.336831,NO,236,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-1.363,-3.959,2.596,,0.303,H,A,1.51,-0.76,1.87,,48.48,AHH,-1.81267,0.100394,0.0088796,0.336831 kka2_1:8_W236K,kka2_1:8_236,Kka2,kka2_1:8,P00552,0.336831,NO,236,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-1.363,-3.959,2.596,,0.303,H,A,1.51,-0.76,1.87,,48.48,AHH,-1.81267,0.100394,0.0088796,0.336831 kka2_1:2_E59V,kka2_1:2_59,Kka2,kka2_1:2,P00552,0.3369,NO,59,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-0.952,-3.591,2.639,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.295029,0.00280355,0.3369 beta-lactamase_2500_L219Y,beta-lactamase_2500_219,TEM-1,beta-lactamase_2500,P62593,0.33691,NO,219,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.313,-3.958,2.645,,,I,A,0.55,-0.51,35.994,35.994,74.48,HHB,-1.21533,0.361275,0.00664345,0.33691 kka2_1:1_L39K,kka2_1:1_39,Kka2,kka2_1:1,P00552,0.337012,NO,39,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.223,-3.871,2.648,,,E,B,0.55,-1.21,0.925,,71.59,BHP,-1.69167,0.520039,0.00493618,0.337012 kka2_1:1_P12C,kka2_1:1_12,Kka2,kka2_1:1,P00552,0.337035,NO,12,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.853,-4.98,4.127,,,.,B,0.52,1.25,0.261,,48.11,POH,-1.80767,0.520039,0.00500011,0.337035 kka2_1:1_D90N,kka2_1:1_90,Kka2,kka2_1:1,P00552,0.337048,NO,90,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.459,-2.125,-0.334,,0.104,E,B,0.75,0.73,6.085,,64.39,BAH,-1.72833,0.520039,0.00583842,0.337048 beta-lactamase_A15D,beta-lactamase_15,TEM-1,beta-lactamase,P62593,0.337088,NO,15,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.654,-3.648,1.994,,,,,,,31.998,31.998,93.01,HHH,-2.10833,0.221079,0.00248966,0.337088 kka2_1:2_E262T,kka2_1:2_262,Kka2,kka2_1:2,P00552,0.337109,NO,262,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-0.829,-3.473,2.644,,0.059,G,A,1.04,-0.18,2.383,,42.42,AAH,-0.816,0.295029,0.0191586,0.337109 hsp90_G584E,hsp90_584,hsp90,hsp90,P02829,0.337133,NO,584,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-2.511,-2.818,0,5.20094,0.414,S,b,0.84,0.33,,,,HOH,-3.32733,0.368192,0.000222939,0.337133 kka2_1:1_R239I,kka2_1:1_239,Kka2,kka2_1:1,P00552,0.33716,NO,239,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.949,-3.142,0.193,,0.15,H,A,1.2,-0.31,0.477,,71.59,ABH,-2.23,0.520039,0.00835326,0.33716 beta-lactamase_625_F64L,beta-lactamase_625_64,TEM-1,beta-lactamase_625,P62593,0.337225,NO,64,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-0.841,-2.908,2.067,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.213352,0.000947691,0.337225 kka2_1:8_G233A,kka2_1:8_233,Kka2,kka2_1:8,P00552,0.337326,NO,233,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.748,-2.995,2.247,,0.172,,b,0.75,-0.27,1.134,,49.24,HOO,-1.72067,0.100394,0.00232366,0.337326 kka2_1:8_G233A,kka2_1:8_233,Kka2,kka2_1:8,P00552,0.337326,NO,233,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.748,-2.995,2.247,,0.172,,b,0.75,-0.27,1.134,,49.24,HOO,-1.72067,0.100394,0.00232366,0.337326 Pab1_K131I,Pab1_131,Pab1,Pab1,P04147,0.337393,NO,131,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.083,-3.827,2.744,,0.462,E,B,1.82,0.57,,,,HBP,-1.12467,0.175299,0.000349395,0.337393 kka2_1:1_G205I,kka2_1:1_205,Kka2,kka2_1:1,P00552,0.337397,NO,205,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.596,-4.264,3.668,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.520039,0.00221855,0.337397 kka2_1:2_L123A,kka2_1:2_123,Kka2,kka2_1:2,P00552,0.337461,NO,123,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.888,-3.161,2.273,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.295029,0.00325188,0.337461 kka2_1:2_P98F,kka2_1:2_98,Kka2,kka2_1:2,P00552,0.337492,NO,98,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.526,-4.51,2.984,,0.391,S,B,0.52,-0.65,2.82,,63.26,HOO,-1.19167,0.295029,0.00622754,0.337492 beta-lactamase_S104I,beta-lactamase_104,TEM-1,beta-lactamase,P62593,0.337524,NO,104,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.015,-3.786,2.771,4.92365,0.04,,b,0.82,0.57,4.02,,63.29,HPO,-1.05267,0.221079,0.00218083,0.337524 kka2_1:1_W24H,kka2_1:1_24,Kka2,kka2_1:1,P00552,0.337562,NO,24,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-1.779,-4.882,3.103,,0.477,E,B,0.47,-0.21,2.375,,56.06,AHH,-2.24467,0.520039,0.00631564,0.337562 kka2_1:8_G233Q,kka2_1:8_233,Kka2,kka2_1:8,P00552,0.337573,NO,233,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.748,-4.098,3.35,,0.172,,b,0.75,-0.27,1.134,,49.24,HOO,-1.72067,0.100394,0.00232366,0.337573 kka2_1:8_G233Q,kka2_1:8_233,Kka2,kka2_1:8,P00552,0.337573,NO,233,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.748,-4.098,3.35,,0.172,,b,0.75,-0.27,1.134,,49.24,HOO,-1.72067,0.100394,0.00232366,0.337573 beta-lactamase_G242H,beta-lactamase_242,TEM-1,beta-lactamase,P62593,0.337591,NO,242,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.319,-4.469,3.15,4.68003,,E,B,0.87,-1.05,1.079,,50,BOH,-1.428,0.221079,0.00452879,0.337591 kka2_1:2_D159W,kka2_1:2_159,Kka2,kka2_1:2,P00552,0.337598,NO,159,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.82,-5.531,4.711,,0.28,.,B,0.75,1.25,0.899,,48.11,HAA,-1.48333,0.295029,0.0030485,0.337598 beta-lactamase_156_S241K,beta-lactamase_156_241,TEM-1,beta-lactamase_156,P62593,0.337636,NO,241,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.111618,0.00452736,0.337636 beta-lactamase_156_A133N,beta-lactamase_156_133,TEM-1,beta-lactamase_156,P62593,0.337643,NO,133,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.186,-3.758,2.572,,,H,A,0.46,-0.86,0.805,,67.83,HHP,-0.988333,0.111618,0.00468022,0.337643 beta-lactamase_625_L223P,beta-lactamase_625_223,TEM-1,beta-lactamase_625,P62593,0.337644,NO,223,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.055,-4.101,3.046,,0.27,,B,0.55,0.09,1.633,,74.48,HHO,-1.35033,0.213352,0.00372793,0.337644 kka2_1:1_G55T,kka2_1:1_55,Kka2,kka2_1:1,P00552,0.337661,NO,55,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.625,-3.642,2.017,,0.517,S,b,0.29,1.19,4.035,,63.64,POH,-2.05967,0.520039,0.00667877,0.337661 beta-lactamase_156_A282P,beta-lactamase_156_282,TEM-1,beta-lactamase_156,P62593,0.337669,NO,282,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.111618,0.0449821,0.337669 kka2_1:2_C131L,kka2_1:2_131,Kka2,kka2_1:2,P00552,0.337674,NO,131,C,L,CL,Special,Hydrophobic,5.07,9.7088,4.6388,198,121,131,10,108.5,166.7,58.2,-0.831,-3.161,2.33,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.295029,0.00170814,0.337674 kka2_1:1_D157V,kka2_1:1_157,Kka2,kka2_1:1,P00552,0.33771,NO,157,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.993,-3.837,2.844,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.520039,0.0042313,0.33771 kka2_1:4_F203R,kka2_1:4_203,Kka2,kka2_1:4,P00552,0.337723,NO,203,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-0.911,-4.185,3.274,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.168804,0.00318738,0.337723 kka2_1:1_C192E,kka2_1:1_192,Kka2,kka2_1:1,P00552,0.337778,NO,192,C,E,CE,Special,negativeCharge,5.07,3.22,-1.85,170,121,147,26,108.5,138.4,29.9,-1.067,-3.955,2.888,,0.095,.,B,0.46,-0.75,2.749,,50,HOH,-0.960333,0.520039,0.00485428,0.337778 beta-lactamase_625_V72G,beta-lactamase_625_72,TEM-1,beta-lactamase_625,P62593,0.33781,NO,72,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.658,-3.477,1.819,,,H,A,0.44,-1.03,0.981,,65.73,BHH,-1.32167,0.213352,0.00501194,0.33781 kka2_1:2_E235G,kka2_1:2_235,Kka2,kka2_1:2,P00552,0.337818,NO,235,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.955,-2.889,0.934,,0.631,H,A,1.04,0.12,26.048,26.048,65.53,OAH,-2.07267,0.295029,0.0102806,0.337818 beta-lactamase_625_T179K,beta-lactamase_625_179,TEM-1,beta-lactamase_625,P62593,0.337822,NO,179,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.085,-3.486,2.401,,,E,B,0.22,-1.38,0.367,,73.08,PPH,-1.557,0.213352,0.00226045,0.337822 kka2_1:1_G210I,kka2_1:1_210,Kka2,kka2_1:1,P00552,0.337865,NO,210,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.095,-4.061,2.966,,0.103,T,A,0.29,-0.62,14.483,14.483,50,OOB,-0.966667,0.520039,0.00598378,0.337865 kka2_1:1_F203Q,kka2_1:1_203,Kka2,kka2_1:1,P00552,0.33789,NO,203,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-0.911,-4.376,3.465,,0.26,E,B,0.58,-0.92,7.323,,63.64,BHP,-1.34167,0.520039,0.00318738,0.33789 kka2_1:1_V97E,kka2_1:1_97,Kka2,kka2_1:1,P00552,0.337917,NO,97,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.453,-3.923,2.47,,0.083,,B,1.48,-0.83,13.576,13.576,53.03,AHO,-1.85067,0.520039,0.00737869,0.337917 kka2_1:2_D227L,kka2_1:2_227,Kka2,kka2_1:2,P00552,0.337965,NO,227,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.758,-3.54,1.782,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.295029,0.00745029,0.337965 kka2_1:1_A110H,kka2_1:1_110,Kka2,kka2_1:1,P00552,0.337993,NO,110,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.064,-3.65,1.586,,0.175,H,A,1.04,-1.19,11.755,,71.59,OHA,-1.91867,0.520039,0.00759851,0.337993 kka2_1:2_V214E,kka2_1:2_214,Kka2,kka2_1:2,P00552,0.338016,NO,214,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.261,-3.897,2.636,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.295029,0.00692782,0.338016 kka2_1:1_G201Y,kka2_1:1_201,Kka2,kka2_1:1,P00552,0.338033,NO,201,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.56,-4.462,2.902,,0.149,T,l,0.29,-0.57,16.092,16.092,52.65,POB,-1.92233,0.520039,0.00820117,0.338033 kka2_1:1_G210D,kka2_1:1_210,Kka2,kka2_1:1,P00552,0.33805,NO,210,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.095,-3.632,2.537,,0.103,T,A,0.29,-0.62,14.483,14.483,50,OOB,-0.966667,0.520039,0.00598378,0.33805 kka2_1:8_L174I,kka2_1:8_174,Kka2,kka2_1:8,P00552,0.338067,NO,174,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.952,-3.013,2.061,,,H,A,1.59,-0.31,1.204,,51.89,BHB,-2.08533,0.100394,0.00438501,0.338067 kka2_1:8_L174I,kka2_1:8_174,Kka2,kka2_1:8,P00552,0.338067,NO,174,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.952,-3.013,2.061,,,H,A,1.59,-0.31,1.204,,51.89,BHB,-2.08533,0.100394,0.00438501,0.338067 beta-lactamase_2500_E119V,beta-lactamase_2500_119,TEM-1,beta-lactamase_2500,P62593,0.338113,NO,119,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.412,-3.661,2.249,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.361275,0.00386966,0.338113 kka2_1:4_F171I,kka2_1:4_171,Kka2,kka2_1:4,P00552,0.338156,NO,171,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.326,-2.784,1.458,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.168804,0.00821426,0.338156 kka2_1:1_S204E,kka2_1:1_204,Kka2,kka2_1:1,P00552,0.338221,NO,204,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.353,-3.494,2.141,,0.144,E,A,0.27,-1.2,3.022,,65.53,HPO,-0.953333,0.520039,0.00881794,0.338221 beta-lactamase_2500_P224C,beta-lactamase_2500_224,TEM-1,beta-lactamase_2500,P62593,0.338243,NO,224,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.893,-5.08,4.187,,0.383,,B,0.52,-0.3,2.666,,74.48,HOH,-1.26433,0.361275,0.00189564,0.338243 kka2_1:2_M178D,kka2_1:2_178,Kka2,kka2_1:2,P00552,0.338313,NO,178,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-3.206,-3.894,0.688,,0.554,.,b,0.55,0.68,3.152,,71.59,BHO,-2.154,0.295029,0.00717253,0.338313 kka2_1:8_V153K,kka2_1:8_153,Kka2,kka2_1:8,P00552,0.338314,NO,153,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.092,-3.83,2.738,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.100394,0.00501119,0.338314 kka2_1:8_V153K,kka2_1:8_153,Kka2,kka2_1:8,P00552,0.338314,NO,153,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.092,-3.83,2.738,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.100394,0.00501119,0.338314 WW_domain_A180V,WW_domain_180,Yap65,WW_domain,P46937,0.33841,NO,180,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.242,-2.919,1.677,6.02829,,,,,,0.627,,23.61,HHB,-1.37767,0.153962,0.00413929,0.33841 Pab1_F129S,Pab1_129,Pab1,Pab1,P04147,0.338454,NO,129,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.269,-3.481,2.212,,0.219,E,B,0.03,-0.07,1.307,,73.83,HHH,-1.27533,0.175299,0.000625182,0.338454 beta-lactamase_156_M66W,beta-lactamase_156_66,TEM-1,beta-lactamase_156,P62593,0.33852,NO,66,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.362,-5.087,3.725,,0.013,,A,0.55,-0.7,1.94,,73.08,OHH,-1.49567,0.111618,0.00412876,0.33852 beta-lactamase_2500_G141F,beta-lactamase_2500_141,TEM-1,beta-lactamase_2500,P62593,0.338527,NO,141,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.828,-4.352,3.524,,0.575,T,l,0.29,-0.28,1.493,,64.69,HOO,-1.08933,0.361275,0.0012419,0.338527 kka2_1:8_Y257L,kka2_1:8_257,Kka2,kka2_1:8,P00552,0.33856,NO,257,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-1.064,-3.141,2.077,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.100394,0.0148191,0.33856 kka2_1:8_Y257L,kka2_1:8_257,Kka2,kka2_1:8,P00552,0.33856,NO,257,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-1.064,-3.141,2.077,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.100394,0.0148191,0.33856 kka2_1:1_Q163D,kka2_1:1_163,Kka2,kka2_1:1,P00552,0.338672,NO,163,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.162,-3.807,1.645,,0.58,T,B,0.64,1.85,2.779,,64.02,BPO,-1.78333,0.520039,0.00719507,0.338672 kka2_1:8_L232T,kka2_1:8_232,Kka2,kka2_1:8,P00552,0.338683,NO,232,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.514,-3.677,2.163,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.100394,0.00800103,0.338683 kka2_1:8_L232T,kka2_1:8_232,Kka2,kka2_1:8,P00552,0.338683,NO,232,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.514,-3.677,2.163,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.100394,0.00800103,0.338683 kka2_1:4_Y22D,kka2_1:4_22,Kka2,kka2_1:4,P00552,0.338684,NO,22,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-1.583,-3.909,2.326,,0.122,.,B,0.21,-0.8,1.838,,65.53,OHA,-1.80333,0.168804,0.00598977,0.338684 beta-lactamase_M209I,beta-lactamase_209,TEM-1,beta-lactamase,P62593,0.338688,NO,209,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.442,-3.121,1.679,5.44502,,H,A,1.75,-0.97,1.402,,64.69,HHA,-1.52633,0.221079,0.00625021,0.338688 Ubiquitin_I36G,Ubiquitin_36,Uba1,Ubiquitin,P0CG48,0.33871,NO,36,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.477,-3.534,2.057,5.1035,0.203,,B,0.27,-0.22,1.552,,30.8,OHO,-1.30767,0.205827,0.000630555,0.33871 Ubiquitin_L71H,Ubiquitin_71,Uba1,Ubiquitin,P0CG48,0.33871,NO,71,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.647,-3.258,1.611,5.02588,0.591,E,B,2.89,-0.69,4.365,,34.31,HHB,-1.85167,0.205827,0.000949314,0.33871 Ubiquitin_L73F,Ubiquitin_73,Uba1,Ubiquitin,P0CG48,0.33871,NO,73,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.801,-2.78,0.979,5.27116,0.518,,B,0.77,1,10.519,10.519,34.31,BHB,-1.858,0.205827,0.000710624,0.33871 Ubiquitin_L8K,Ubiquitin_8,Uba1,Ubiquitin,P0CG48,0.33871,NO,8,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.723,-3.606,1.883,5.28016,0.664,T,A,0.08,-0.34,0.664,,29.05,PHP,-1.51567,0.205827,0.000726165,0.33871 Ubiquitin_R72F,Ubiquitin_72,Uba1,Ubiquitin,P0CG48,0.33871,NO,72,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.034,-3.178,1.144,5.19484,0.077,,B,1.41,-0.1,9.638,9.638,42.77,HBH,-1.82733,0.205827,0.000768249,0.33871 beta-lactamase_156_C75W,beta-lactamase_156_75,TEM-1,beta-lactamase_156,P62593,0.33874,NO,75,C,W,CW,Special,Hydrophobic,5.07,5.89,0.82,215,121,204,83,108.5,227.8,119.3,-1.245,-5.246,4.001,,,H,A,0.46,-0.87,0.876,,50,HOO,-1.24333,0.111618,0.0034616,0.33874 kka2_1:4_S104Y,kka2_1:4_104,Kka2,kka2_1:4,P00552,0.338757,NO,104,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.436,-4.278,2.842,,0.536,T,A,0.27,-1.11,0.357,,63.64,HPP,-1.91433,0.168804,0.00555207,0.338757 beta-lactamase_0_G141Y,beta-lactamase_0_141,TEM-1,beta-lactamase_0,P62593,0.338798,NO,141,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.828,-4.424,3.596,,0.575,T,l,0.29,-0.28,0.722,,64.69,HOO,-1.08933,0.0500837,0.0012419,0.338798 beta-lactamase_2500_S266W,beta-lactamase_2500_266,TEM-1,beta-lactamase_2500,P62593,0.338803,NO,266,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.361275,0.0140785,0.338803 kka2_1:1_Y22G,kka2_1:1_22,Kka2,kka2_1:1,P00552,0.338808,NO,22,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-1.583,-2.411,0.828,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.520039,0.00598977,0.338808 kka2_1:1_S40M,kka2_1:1_40,Kka2,kka2_1:1,P00552,0.33894,NO,40,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.645,-4.831,2.186,,0.32,E,B,0.27,-0.9,25.997,25.997,71.59,HPH,-1.91567,0.520039,0.00693477,0.33894 kka2_1:1_D220C,kka2_1:1_220,Kka2,kka2_1:1,P00552,0.33897,NO,220,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.787,-5.083,4.296,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.520039,0.00158066,0.33897 kka2_1:2_P98Y,kka2_1:2_98,Kka2,kka2_1:2,P00552,0.339022,NO,98,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.526,-4.481,2.955,,0.391,S,B,0.52,-0.65,2.82,,63.26,HOO,-1.19167,0.295029,0.00622754,0.339022 kka2_1:1_A71I,kka2_1:1_71,Kka2,kka2_1:1,P00552,0.339049,NO,71,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.824,-4.1,2.276,,0.553,H,A,0.46,0.08,9.788,,64.39,HHP,-1.74033,0.520039,0.00727707,0.339049 Pab1_F146D,Pab1_146,Pab1,Pab1,P04147,0.339073,NO,146,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.149,-3.736,2.587,,0.006,H,A,,0.75,,,,PHP,-1.161,0.175299,0.000329265,0.339073 kka2_1:4_V49Y,kka2_1:4_49,Kka2,kka2_1:4,P00552,0.33909,NO,49,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.614,-4.126,2.512,,,E,B,0.44,-0.77,1.233,,64.39,HHB,-1.3,0.168804,0.00615685,0.33909 kka2_1:1_G30W,kka2_1:1_30,Kka2,kka2_1:1,P00552,0.339107,NO,30,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.596,-5.126,4.53,,0.54,S,g,0.29,3.76,,,,HOO,-1.51133,0.520039,0.00159208,0.339107 beta-lactamase_2500_L218F,beta-lactamase_2500_218,TEM-1,beta-lactamase_2500,P62593,0.339115,NO,218,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.391,-2.985,1.594,,,I,b,0.55,-0.53,9.151,9.151,74.48,OHH,-1.58867,0.361275,0.00618274,0.339115 beta-lactamase_625_S241F,beta-lactamase_625_241,TEM-1,beta-lactamase_625,P62593,0.339128,NO,241,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.213352,0.00452736,0.339128 kka2_1:4_A215Q,kka2_1:4_215,Kka2,kka2_1:4,P00552,0.339154,NO,215,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.968,-3.954,2.986,,0.039,E,B,0.46,-0.59,0.754,,50.38,HHA,-1.00467,0.168804,0.00529129,0.339154 kka2_1:1_I207A,kka2_1:1_207,Kka2,kka2_1:1,P00552,0.339209,NO,207,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.175,-3.122,1.947,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.520039,0.00611824,0.339209 kka2_1:1_Q26V,kka2_1:1_26,Kka2,kka2_1:1,P00552,0.339268,NO,26,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.18,-3.715,1.535,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.520039,0.00708962,0.339268 kka2_1:1_R217A,kka2_1:1_217,Kka2,kka2_1:1,P00552,0.339335,NO,217,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.158,-3.215,2.057,,0.252,T,A,1.2,-0.59,0.381,,52.27,ABH,-1.127,0.520039,0.0047191,0.339335 kka2_1:1_V75C,kka2_1:1_75,Kka2,kka2_1:1,P00552,0.339342,NO,75,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-2.06,-4.904,2.844,,0.042,.,B,0.44,-0.2,2.815,,71.59,OHO,-1.563,0.520039,0.00693733,0.339342 beta-lactamase_2500_I280T,beta-lactamase_2500_280,TEM-1,beta-lactamase_2500,P62593,0.339404,NO,280,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.361275,0.0530888,0.339404 kka2_1:8_A144W,kka2_1:8_144,Kka2,kka2_1:8,P00552,0.339421,NO,144,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.859,-5.395,4.536,,,H,A,1.04,0.21,1.118,,52.65,BHB,-1.72933,0.100394,0.00231095,0.339421 kka2_1:8_A144W,kka2_1:8_144,Kka2,kka2_1:8,P00552,0.339421,NO,144,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.859,-5.395,4.536,,,H,A,1.04,0.21,1.118,,52.65,BHB,-1.72933,0.100394,0.00231095,0.339421 kka2_1:8_F263H,kka2_1:8_263,Kka2,kka2_1:8,P00552,0.339421,NO,263,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-0.911,-4.571,3.66,,0.006,G,A,1.62,-0.12,0.928,,45.83,AHH,-0.92,0.100394,0.0172454,0.339421 kka2_1:8_F263H,kka2_1:8_263,Kka2,kka2_1:8,P00552,0.339421,NO,263,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-0.911,-4.571,3.66,,0.006,G,A,1.62,-0.12,0.928,,45.83,AHH,-0.92,0.100394,0.0172454,0.339421 kka2_1:4_K112N,kka2_1:4_112,Kka2,kka2_1:4,P00552,0.339423,NO,112,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-2.491,-3.976,1.485,,0.076,H,A,2.34,-1.37,0.39,,56.06,ABH,-2.00133,0.168804,0.00645389,0.339423 kka2_1:4_V214E,kka2_1:4_214,Kka2,kka2_1:4,P00552,0.339472,NO,214,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.261,-3.897,2.636,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.168804,0.00692782,0.339472 kka2_1:4_A117L,kka2_1:4_117,Kka2,kka2_1:4,P00552,0.339475,NO,117,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.828,-3.117,2.289,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.168804,0.00282984,0.339475 beta-lactamase_2500_S104R,beta-lactamase_2500_104,TEM-1,beta-lactamase_2500,P62593,0.339518,NO,104,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.015,-3.804,2.789,,0.04,,b,0.27,0.57,1.133,,63.29,HPO,-1.05267,0.361275,0.00218083,0.339518 beta-lactamase_0_G76L,beta-lactamase_0_76,TEM-1,beta-lactamase_0,P62593,0.33953,NO,76,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.189,-3.521,2.332,,,H,A,0.29,-0.67,1.188,,67.83,OOH,-1.22267,0.0500837,0.00476637,0.33953 beta-lactamase_2500_M115F,beta-lactamase_2500_115,TEM-1,beta-lactamase_2500,P62593,0.339542,NO,115,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.389,-2.82,1.431,,0.019,E,B,0.55,0.08,3.261,,69.58,OHP,-1.25433,0.361275,0.0034337,0.339542 beta-lactamase_G239K,beta-lactamase_239,TEM-1,beta-lactamase,P62593,0.339619,NO,239,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.819,-3.625,2.806,4.85529,0.115,T,l,0.77,-0.62,1.817,,42.31,BOP,-1.45267,0.221079,0.00213852,0.339619 beta-lactamase_F64C,beta-lactamase_64,TEM-1,beta-lactamase,P62593,0.339641,NO,64,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-0.841,-4.862,4.021,5.70769,0.006,E,B,1.33,-0.95,,,,BHO,-0.892667,0.221079,0.000947691,0.339641 beta-lactamase_L135G,beta-lactamase_135,TEM-1,beta-lactamase,P62593,0.339692,NO,135,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.002,-3.837,2.835,5.28497,0.117,H,A,1.07,-0.58,0.697,,43.71,PHH,-1.03767,0.221079,0.00244423,0.339692 kka2_1:1_T225W,kka2_1:1_225,Kka2,kka2_1:1,P00552,0.339704,NO,225,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.393,-5.412,3.019,,0.036,H,A,0.22,-1.22,4.554,,63.64,HPB,-1.58733,0.520039,0.0113598,0.339704 kka2_1:2_V198G,kka2_1:2_198,Kka2,kka2_1:2,P00552,0.339812,NO,198,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.719,-3.368,1.649,,0.05,E,B,1.48,-0.95,1.074,,56.06,HHA,-1.88667,0.295029,0.00835002,0.339812 kka2_1:2_L123S,kka2_1:2_123,Kka2,kka2_1:2,P00552,0.339845,NO,123,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.888,-3.661,2.773,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.295029,0.00325188,0.339845 kka2_1:1_C209T,kka2_1:1_209,Kka2,kka2_1:1,P00552,0.339848,NO,209,C,T,CT,Special,Polar,5.07,5.6,0.53,149,121,119,-2,108.5,116.1,7.6,-0.906,-3.473,2.567,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.520039,0.00260862,0.339848 beta-lactamase_2500_F70Q,beta-lactamase_2500_70,TEM-1,beta-lactamase_2500,P62593,0.339918,NO,70,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.169,-4.201,3.032,,,H,A,0.58,-1.34,1.918,,63.99,PHB,-0.980667,0.361275,0.00193499,0.339918 beta-lactamase_I229H,beta-lactamase_229,TEM-1,beta-lactamase,P62593,0.339957,NO,229,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.267,-4.969,3.702,5.0911,0.083,E,B,1,-0.76,1.114,,50,HHH,-1.58767,0.221079,0.00477249,0.339957 kka2_1:4_L123A,kka2_1:4_123,Kka2,kka2_1:4,P00552,0.339975,NO,123,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.888,-3.161,2.273,,0.007,H,A,0.55,-0.4,1.447,,48.86,BHB,-1.301,0.168804,0.00325188,0.339975 beta-lactamase_625_R159P,beta-lactamase_625_159,TEM-1,beta-lactamase_625,P62593,0.340018,NO,159,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-0.94,-3.905,2.965,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.213352,0.00108472,0.340018 kka2_1:8_F264T,kka2_1:8_264,Kka2,kka2_1:8,P00552,0.340035,NO,264,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.02,-3.729,2.709,,0.296,,?,1.62,0.02,1.553,,71.59,HHO,-0.9655,0.100394,,0.340035 kka2_1:8_F264T,kka2_1:8_264,Kka2,kka2_1:8,P00552,0.340035,NO,264,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.02,-3.729,2.709,,0.296,,?,1.62,0.02,1.553,,71.59,HHO,-0.9655,0.100394,,0.340035 kka2_1:1_V153Q,kka2_1:1_153,Kka2,kka2_1:1,P00552,0.34007,NO,153,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.092,-4.272,3.18,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.520039,0.00501119,0.34007 kka2_1:1_W15N,kka2_1:1_15,Kka2,kka2_1:1,P00552,0.340146,NO,15,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-1.392,-4.342,2.95,,0.01,G,A,0.47,0.15,20.149,20.149,52.27,HHH,-2.10533,0.520039,0.00585505,0.340146 beta-lactamase_2500_D48V,beta-lactamase_2500_48,TEM-1,beta-lactamase_2500,P62593,0.340215,NO,48,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.101,-3.719,2.618,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.361275,0.0027273,0.340215 beta-lactamase_625_D161W,beta-lactamase_625_161,TEM-1,beta-lactamase_625,P62593,0.340219,NO,161,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.891,-5.546,4.655,,0.341,,A,0.75,-0.52,4.655,,61.19,HAB,-0.961333,0.213352,0.000897697,0.340219 Pab1_F170S,Pab1_170,Pab1,Pab1,P04147,0.340219,NO,170,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.269,-3.481,2.212,,0.331,E,B,0.87,-1.31,2.061,,79.72,OHH,-1.06367,0.175299,0.000540225,0.340219 beta-lactamase_2500_R162E,beta-lactamase_2500_162,TEM-1,beta-lactamase_2500,P62593,0.340252,NO,162,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.016,-3.337,2.321,,0.124,S,B,1.2,-0.37,6.199,,64.69,ABH,-1.25,0.361275,0.000561334,0.340252 beta-lactamase_2500_N168D,beta-lactamase_2500_168,TEM-1,beta-lactamase_2500,P62593,0.340267,NO,168,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-1.029,-3.143,2.114,,0.113,G,A,0.61,-0.4,2.9,,44.41,HPA,-1.13233,0.361275,0.00288667,0.340267 beta-lactamase_625_L218K,beta-lactamase_625_218,TEM-1,beta-lactamase_625,P62593,0.3404,NO,218,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.391,-2.186,0.795,,,I,b,0.55,-0.53,17.202,17.202,74.48,OHH,-1.58867,0.213352,0.00618274,0.3404 kka2_1:4_F263Y,kka2_1:4_263,Kka2,kka2_1:4,P00552,0.340421,NO,263,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-0.911,-3.189,2.278,,0.006,G,A,0.58,-0.12,2.284,,45.83,AHH,-0.92,0.168804,0.0172454,0.340421 kka2_1:1_F240G,kka2_1:1_240,Kka2,kka2_1:1,P00552,0.340435,NO,240,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-0.911,-3.675,2.764,,,H,A,1.62,-1.21,5.798,,50.38,BHH,-1.67267,0.520039,0.00552543,0.340435 beta-lactamase_2500_L248A,beta-lactamase_2500_248,TEM-1,beta-lactamase_2500,P62593,0.340464,NO,248,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.361275,0.00428493,0.340464 kka2_1:4_L102S,kka2_1:4_102,Kka2,kka2_1:4,P00552,0.340466,NO,102,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.804,-3.637,2.833,,,T,A,0.55,-1.17,0.65,,42.42,AHH,-1.398,0.168804,0.00201332,0.340466 kka2_1:2_H135T,kka2_1:2_135,Kka2,kka2_1:2,P00552,0.340492,NO,135,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-1.331,-3.65,2.319,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.295029,0.00532566,0.340492 kka2_1:8_L232D,kka2_1:8_232,Kka2,kka2_1:8,P00552,0.340525,NO,232,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.514,-4.122,2.608,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.100394,0.00800103,0.340525 kka2_1:8_L232D,kka2_1:8_232,Kka2,kka2_1:8,P00552,0.340525,NO,232,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.514,-4.122,2.608,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.100394,0.00800103,0.340525 beta-lactamase_625_G281Q,beta-lactamase_625_281,TEM-1,beta-lactamase_625,P62593,0.340547,NO,281,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.213352,0.0406482,0.340547 kka2_1:1_A119P,kka2_1:1_119,Kka2,kka2_1:1,P00552,0.340582,NO,119,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.073,-3.813,2.74,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.520039,0.00441074,0.340582 WW_domain_W177S,WW_domain_177,Yap65,WW_domain,P46937,0.340603,NO,177,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-1.198,-3.613,2.415,5.18137,,,,,,,,,OHA,-1.197,0.153962,0.00198549,0.340603 kka2_1:2_L107F,kka2_1:2_107,Kka2,kka2_1:2,P00552,0.340615,NO,107,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.238,-3.877,2.639,,0.197,,B,1.59,-1.1,2.68,,71.59,BHH,-2.143,0.295029,0.00561937,0.340615 kka2_1:2_D261Q,kka2_1:2_261,Kka2,kka2_1:2,P00552,0.340646,NO,261,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.708,-3.703,2.995,,0.146,G,A,0.75,-0.33,,,,HAA,-0.759333,0.295029,0.0224846,0.340646 kka2_1:1_L70F,kka2_1:1_70,Kka2,kka2_1:1,P00552,0.340679,NO,70,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.017,-3.762,2.745,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.520039,0.00411884,0.340679 kka2_1:2_L60Q,kka2_1:2_60,Kka2,kka2_1:2,P00552,0.340797,NO,60,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.997,-4.233,3.236,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.295029,0.00262176,0.340797 kka2_1:1_L223A,kka2_1:1_223,Kka2,kka2_1:1,P00552,0.340825,NO,223,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.861,-3.151,2.29,,,H,A,0.55,-1.24,1.268,,50,HHH,-0.854333,0.520039,0.00253574,0.340825 kka2_1:1_L223T,kka2_1:1_223,Kka2,kka2_1:1,P00552,0.340825,NO,223,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.861,-3.494,2.633,,,H,A,0.55,-1.24,1.268,,50,HHH,-0.854333,0.520039,0.00253574,0.340825 kka2_1:2_G201Q,kka2_1:2_201,Kka2,kka2_1:2,P00552,0.340862,NO,201,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.56,-4.001,2.441,,0.149,T,l,0.29,-0.57,16.092,16.092,52.65,POB,-1.92233,0.295029,0.00820117,0.340862 kka2_1:2_S204F,kka2_1:2_204,Kka2,kka2_1:2,P00552,0.340893,NO,204,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.353,-4.232,2.879,,0.144,E,A,0.27,-1.2,2.442,,65.53,HPO,-0.953333,0.295029,0.00881794,0.340893 beta-lactamase_39_F64R,beta-lactamase_39_64,TEM-1,beta-lactamase_39,P62593,0.340959,NO,64,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-0.841,-4.158,3.317,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.0495842,0.000947691,0.340959 kka2_1:8_F206T,kka2_1:8_206,Kka2,kka2_1:8,P00552,0.341015,NO,206,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.349,-3.71,2.361,,0.006,E,B,1.62,-1.21,1.052,,63.64,OHH,-1.04,0.100394,0.00936868,0.341015 kka2_1:8_F206T,kka2_1:8_206,Kka2,kka2_1:8,P00552,0.341015,NO,206,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.349,-3.71,2.361,,0.006,E,B,1.62,-1.21,1.052,,63.64,OHH,-1.04,0.100394,0.00936868,0.341015 kka2_1:2_N58C,kka2_1:2_58,Kka2,kka2_1:2,P00552,0.341053,NO,58,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-2.641,-2.921,0.28,,0.131,S,A,0.43,0.72,5.729,,71.59,HPA,-1.83033,0.295029,0.00793425,0.341053 beta-lactamase_625_A235F,beta-lactamase_625_235,TEM-1,beta-lactamase_625,P62593,0.341074,NO,235,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.266,-4.199,2.933,,0.32,E,B,0.46,-0.86,0.281,,50,OHO,-0.89,0.213352,0.00493474,0.341074 beta-lactamase_2500_Y103D,beta-lactamase_2500_103,TEM-1,beta-lactamase_2500,P62593,0.341081,NO,103,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-1.33,-3.794,2.464,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.361275,0.00443048,0.341081 kka2_1:2_I246H,kka2_1:2_246,Kka2,kka2_1:2,P00552,0.341104,NO,246,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-2.008,-5.017,3.009,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.295029,0.0139479,0.341104 beta-lactamase_625_I280S,beta-lactamase_625_280,TEM-1,beta-lactamase_625,P62593,0.341105,NO,280,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.213352,0.0530888,0.341105 beta-lactamase_G239R,beta-lactamase_239,TEM-1,beta-lactamase,P62593,0.341156,NO,239,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.819,-3.876,3.057,4.85529,0.115,T,l,0.77,-0.62,1.817,,42.31,BOP,-1.45267,0.221079,0.00213852,0.341156 kka2_1:1_P12Y,kka2_1:1_12,Kka2,kka2_1:1,P00552,0.341162,NO,12,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.853,-4.385,3.532,,,.,B,0.52,1.25,0.261,,48.11,POH,-1.80767,0.520039,0.00500011,0.341162 kka2_1:1_L81W,kka2_1:1_81,Kka2,kka2_1:1,P00552,0.341198,NO,81,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.427,-5.367,3.94,,0.46,E,A,0.55,-0.14,0.374,,63.64,HHA,-1.50567,0.520039,0.00805839,0.341198 beta-lactamase_625_S104K,beta-lactamase_625_104,TEM-1,beta-lactamase_625,P62593,0.341282,NO,104,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.015,-3.372,2.357,,0.04,,b,0.27,0.57,1.76,,63.29,HPO,-1.05267,0.213352,0.00218083,0.341282 beta-lactamase_625_L167G,beta-lactamase_625_167,TEM-1,beta-lactamase_625,P62593,0.341357,NO,167,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.138,-3.694,2.556,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.213352,0.00303566,0.341357 beta-lactamase_625_N130A,beta-lactamase_625_130,TEM-1,beta-lactamase_625,P62593,0.341364,NO,130,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-0.798,-3.303,2.505,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.213352,0.000683376,0.341364 beta-lactamase_2500_G265I,beta-lactamase_2500_265,TEM-1,beta-lactamase_2500,P62593,0.341366,NO,265,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.361275,0.00811926,0.341366 kka2_1:1_L259I,kka2_1:1_259,Kka2,kka2_1:1,P00552,0.341396,NO,259,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.088,-3.1,2.012,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.520039,0.0206964,0.341396 beta-lactamase_2500_N274V,beta-lactamase_2500_274,TEM-1,beta-lactamase_2500,P62593,0.341411,NO,274,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.361275,0.0110418,0.341411 kka2_1:1_R173C,kka2_1:1_173,Kka2,kka2_1:1,P00552,0.341421,NO,173,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.407,-5.224,2.817,,0.308,H,A,0.16,-0.13,14.756,14.756,65.53,HBH,-1.70533,0.520039,0.00784999,0.341421 beta-lactamase_156_I258Q,beta-lactamase_156_258,TEM-1,beta-lactamase_156,P62593,0.341464,NO,258,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.111618,0.007931,0.341464 kka2_1:4_D90I,kka2_1:4_90,Kka2,kka2_1:4,P00552,0.341483,NO,90,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.459,-3.293,0.834,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.168804,0.00583842,0.341483 beta-lactamase_L160K,beta-lactamase_160,TEM-1,beta-lactamase,P62593,0.341488,NO,160,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.977,-3.757,2.78,5.32068,0.022,,B,1.75,-0.6,0.895,,44.41,BHA,-0.936,0.221079,0.00193775,0.341488 kka2_1:4_W91I,kka2_1:4_91,Kka2,kka2_1:4,P00552,0.341595,NO,91,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-1.178,-3.942,2.764,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.168804,0.00358653,0.341595 beta-lactamase_2500_L38K,beta-lactamase_2500_38,TEM-1,beta-lactamase_2500,P62593,0.341705,NO,38,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.343,-3.749,2.406,,0.088,H,A,0.55,0.2,2.71,,64.34,PHO,-1.78033,0.361275,0.00373244,0.341705 beta-lactamase_625_W288K,beta-lactamase_625_288,TEM-1,beta-lactamase_625,P62593,0.341716,NO,288,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,,,,,,,,,,,,,BHO,,0.213352,,0.341716 kka2_1:8_A222W,kka2_1:8_222,Kka2,kka2_1:8,P00552,0.341748,NO,222,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.725,-5.351,4.626,,,H,A,1.04,-1.21,,,,HHH,-1.10833,0.100394,0.00207657,0.341748 kka2_1:8_A222W,kka2_1:8_222,Kka2,kka2_1:8,P00552,0.341748,NO,222,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.725,-5.351,4.626,,,H,A,1.04,-1.21,,,,HHH,-1.10833,0.100394,0.00207657,0.341748 beta-lactamase_625_G236I,beta-lactamase_625_236,TEM-1,beta-lactamase_625,P62593,0.341768,NO,236,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.784,-4.139,3.355,,0.241,,b,0.29,-0.59,3.506,,64.69,HOO,-1.025,0.213352,0.00162372,0.341768 Pab1_K131M,Pab1_131,Pab1,Pab1,P04147,0.341775,NO,131,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.083,-4.297,3.214,,0.462,E,B,1.82,0.57,,,,HBP,-1.12467,0.175299,0.000349395,0.341775 kka2_1:2_G210L,kka2_1:2_210,Kka2,kka2_1:2,P00552,0.341833,NO,210,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.095,-3.634,2.539,,0.103,T,A,0.29,-0.62,0.271,,50,OOB,-0.966667,0.295029,0.00598378,0.341833 kka2_1:1_E169S,kka2_1:1_169,Kka2,kka2_1:1,P00552,0.341863,NO,169,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.996,-2.626,0.63,,0.422,H,A,1.04,0.3,7.546,7.546,65.53,HAH,-1.755,0.520039,0.00730086,0.341863 Pab1_N127G,Pab1_127,Pab1,Pab1,P04147,0.341899,NO,127,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-1.079,-2.725,1.646,,0.138,E,B,1.05,-0.51,,,,OPH,-1.13633,0.175299,0.000805159,0.341899 kka2_1:1_V214E,kka2_1:1_214,Kka2,kka2_1:1,P00552,0.341941,NO,214,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.261,-3.897,2.636,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.520039,0.00692782,0.341941 beta-lactamase_625_F58D,beta-lactamase_625_58,TEM-1,beta-lactamase_625,P62593,0.342171,NO,58,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-2.914,-3.846,0.932,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.213352,0.00523369,0.342171 beta-lactamase_M1T,beta-lactamase_1,TEM-1,beta-lactamase,P62593,0.342178,NO,1,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.998,-3.103,1.105,,,,,,,,,,OHP,-1.97,0.221079,0.00162771,0.342178 kka2_1:1_A144F,kka2_1:1_144,Kka2,kka2_1:1,P00552,0.342201,NO,144,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.859,-4.095,3.236,,,H,A,0.46,0.21,0.842,,52.65,BHB,-1.72933,0.520039,0.00231095,0.342201 kka2_1:1_A144H,kka2_1:1_144,Kka2,kka2_1:1,P00552,0.342201,NO,144,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.859,-4.791,3.932,,,H,A,0.46,0.21,0.842,,52.65,BHB,-1.72933,0.520039,0.00231095,0.342201 kka2_1:8_N195H,kka2_1:8_195,Kka2,kka2_1:8,P00552,0.342235,NO,195,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-0.836,-4.094,3.258,,0.037,G,A,0.43,-1.36,1.108,,48.11,OPH,-1.26567,0.100394,0.00276134,0.342235 kka2_1:8_N195H,kka2_1:8_195,Kka2,kka2_1:8,P00552,0.342235,NO,195,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-0.836,-4.094,3.258,,0.037,G,A,0.43,-1.36,1.108,,48.11,OPH,-1.26567,0.100394,0.00276134,0.342235 beta-lactamase_0_A230K,beta-lactamase_0_230,TEM-1,beta-lactamase_0,P62593,0.342241,NO,230,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.154,-3.583,2.429,,0.01,E,B,0.46,-1.17,2.179,,50,HHA,-1.079,0.0500837,0.00516841,0.342241 kka2_1:1_Q136C,kka2_1:1_136,Kka2,kka2_1:1,P00552,0.342263,NO,136,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-3.021,-3.362,0.341,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.520039,0.00624149,0.342263 kka2_1:8_F264G,kka2_1:8_264,Kka2,kka2_1:8,P00552,0.342357,NO,264,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.02,-3.702,2.682,,0.296,,?,1.62,0.02,1.553,,71.59,HHO,-0.9655,0.100394,,0.342357 kka2_1:8_F264G,kka2_1:8_264,Kka2,kka2_1:8,P00552,0.342357,NO,264,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.02,-3.702,2.682,,0.296,,?,1.62,0.02,1.553,,71.59,HHO,-0.9655,0.100394,,0.342357 Pab1_G169M,Pab1_169,Pab1,Pab1,P04147,0.342358,NO,169,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.809,-4.747,3.938,,,E,b,0.35,0.03,,,,HOH,-1.11567,0.175299,0.000302434,0.342358 kka2_1:1_E142V,kka2_1:1_142,Kka2,kka2_1:1,P00552,0.342403,NO,142,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.221,-3.677,1.456,,0.471,H,A,1.52,0.85,3.626,,65.53,HAB,-2.08033,0.520039,0.00748883,0.342403 kka2_1:4_S32I,kka2_1:4_32,Kka2,kka2_1:4,P00552,0.34241,NO,32,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-0.804,-3.814,3.01,,0.768,S,b,0.27,3.75,,,,OPA,-1.74533,0.168804,0.00149998,0.34241 kka2_1:1_G245M,kka2_1:1_245,Kka2,kka2_1:1,P00552,0.342446,NO,245,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.812,-4.937,4.125,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.520039,0.00683899,0.342446 kka2_1:1_A25P,kka2_1:1_25,Kka2,kka2_1:1,P00552,0.342473,NO,25,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.496,-3.994,1.498,,0.427,E,B,0.46,-0.47,6.872,6.872,65.53,HHP,-2.15167,0.520039,0.00595636,0.342473 beta-lactamase_2500_T263R,beta-lactamase_2500_263,TEM-1,beta-lactamase_2500,P62593,0.342502,NO,263,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.361275,0.0110582,0.342502 beta-lactamase_625_A133V,beta-lactamase_625_133,TEM-1,beta-lactamase_625,P62593,0.342518,NO,133,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.186,-3.341,2.155,,,H,A,0.46,-0.86,0.373,,67.83,HHP,-0.988333,0.213352,0.00468022,0.342518 kka2_1:4_A222D,kka2_1:4_222,Kka2,kka2_1:4,P00552,0.342519,NO,222,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.725,-3.722,2.997,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.168804,0.00207657,0.342519 PSD95pdz3_G330Y,PSD95pdz3_330,PSD95pdz3,PSD95pdz3,P31016,0.342554,NO,330,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.008,-4.069,3.061,4.68351,,,,,31.405,,,,OOA,-1.14,0.0758425,0.000962386,0.342554 kka2_1:4_L126F,kka2_1:4_126,Kka2,kka2_1:4,P00552,0.342565,NO,126,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.246,-3.893,2.647,,0.285,S,B,0.55,0.12,0.302,,51.89,PHA,-1.744,0.168804,0.0066485,0.342565 kka2_1:1_L170V,kka2_1:1_170,Kka2,kka2_1:1,P00552,0.342572,NO,170,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.28,-1.716,0.436,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.520039,0.00730791,0.342572 kka2_1:1_L212T,kka2_1:1_212,Kka2,kka2_1:1,P00552,0.342618,NO,212,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.904,-3.451,2.547,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.520039,0.0031426,0.342618 beta-lactamase_L282H,beta-lactamase_282,TEM-1,beta-lactamase,P62593,0.342622,NO,282,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.586,-4.932,3.346,5.16743,0.007,H,A,1.07,0.34,31.31,31.31,63.99,PHH,-1.82367,0.221079,0.0449821,0.342622 beta-lactamase_2500_L188N,beta-lactamase_2500_188,TEM-1,beta-lactamase_2500,P62593,0.3427,NO,188,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.166,-4.122,2.956,,,H,A,0.55,-0.3,17.865,17.865,60.14,PHB,-1.47033,0.361275,0.00295687,0.3427 beta-lactamase_2500_L74C,beta-lactamase_2500_74,TEM-1,beta-lactamase_2500,P62593,0.342715,NO,74,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.296,-4.647,3.351,,,H,A,0.55,-0.91,0.746,,50,HHO,-1.34933,0.361275,0.00493255,0.342715 kka2_1:8_H188A,kka2_1:8_188,Kka2,kka2_1:8,P00552,0.342722,NO,188,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-0.913,-3.329,2.416,,0.006,,A,0.87,-1.02,1.241,,47.73,PBO,-0.927333,0.100394,0.00273139,0.342722 kka2_1:8_H188A,kka2_1:8_188,Kka2,kka2_1:8,P00552,0.342722,NO,188,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-0.913,-3.329,2.416,,0.006,,A,0.87,-1.02,1.241,,47.73,PBO,-0.927333,0.100394,0.00273139,0.342722 kka2_1:1_P194G,kka2_1:1_194,Kka2,kka2_1:1,P00552,0.342809,NO,194,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.846,-3.359,2.513,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.520039,0.00314194,0.342809 kka2_1:1_V49R,kka2_1:1_49,Kka2,kka2_1:1,P00552,0.342812,NO,49,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.614,-4.154,2.54,,,E,B,0.44,-0.77,3.665,3.665,64.39,HHB,-1.3,0.520039,0.00615685,0.342812 kka2_1:1_I246Y,kka2_1:1_246,Kka2,kka2_1:1,P00552,0.34282,NO,246,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-2.008,-4.266,2.258,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.520039,0.0139479,0.34282 kka2_1:1_T85M,kka2_1:1_85,Kka2,kka2_1:1,P00552,0.342883,NO,85,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.165,-4.675,2.51,,0.576,E,B,0.82,1.39,16.653,16.653,71.59,HPA,-2.10133,0.520039,0.00634493,0.342883 kka2_1:1_P98M,kka2_1:1_98,Kka2,kka2_1:1,P00552,0.34291,NO,98,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.526,-4.804,3.278,,0.391,S,B,0.52,-0.65,1.521,,63.26,HOO,-1.19167,0.520039,0.00622754,0.34291 kka2_1:4_F37Q,kka2_1:4_37,Kka2,kka2_1:4,P00552,0.342923,NO,37,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.427,-4.273,2.846,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.168804,0.00586193,0.342923 beta-lactamase_P65E,beta-lactamase_65,TEM-1,beta-lactamase,P62593,0.342935,NO,65,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.894,-3.524,2.63,5.59094,0.098,E,B,0.23,-0.62,0.623,,40.56,HOH,-1.03233,0.221079,0.00152776,0.342935 kka2_1:2_L243G,kka2_1:2_243,Kka2,kka2_1:2,P00552,0.34297,NO,243,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-2.651,-3.604,0.953,,0.277,H,A,1.59,-0.67,13.165,13.165,92.05,HHH,-2.03767,0.295029,0.00884927,0.34297 kka2_1:2_G245K,kka2_1:2_245,Kka2,kka2_1:2,P00552,0.34298,NO,245,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.812,-3.635,2.823,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.295029,0.00683899,0.34298 kka2_1:2_L184I,kka2_1:2_184,Kka2,kka2_1:2,P00552,0.342987,NO,184,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.496,-2.585,1.089,,0.489,E,B,0.55,-0.06,14.044,14.044,63.26,AHH,-1.24833,0.295029,0.00518742,0.342987 kka2_1:1_D159F,kka2_1:1_159,Kka2,kka2_1:1,P00552,0.343019,NO,159,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.82,-4.355,3.535,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.520039,0.0030485,0.343019 kka2_1:1_T225E,kka2_1:1_225,Kka2,kka2_1:1,P00552,0.343029,NO,225,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.393,-3.79,1.397,,0.036,H,A,0.22,-1.22,4.554,,63.64,HPB,-1.58733,0.520039,0.0113598,0.343029 Pab1_N127A,Pab1_127,Pab1,Pab1,P04147,0.343072,NO,127,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-1.079,-3.12,2.041,,0.138,E,B,1.05,-0.51,,,,OPH,-1.13633,0.175299,0.000805159,0.343072 kka2_1:1_E161N,kka2_1:1_161,Kka2,kka2_1:1,P00552,0.343106,NO,161,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.581,-3.715,2.134,,0.829,G,A,1.04,2.24,1.612,,92.05,AAB,-1.861,0.520039,0.00760103,0.343106 beta-lactamase_625_L205T,beta-lactamase_625_205,TEM-1,beta-lactamase_625,P62593,0.343134,NO,205,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.922,-3.476,2.554,,,H,A,0.55,-0.46,3.782,,42.31,PHH,-1.57767,0.213352,0.00255802,0.343134 kka2_1:1_E231M,kka2_1:1_231,Kka2,kka2_1:1,P00552,0.343258,NO,231,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.002,-4.813,2.811,,0.503,H,A,1.04,-0.23,25.629,25.629,63.26,AAH,-2.06267,0.520039,0.00732383,0.343258 kka2_1:1_P249E,kka2_1:1_249,Kka2,kka2_1:1,P00552,0.343262,NO,249,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.867,-3.804,1.937,,0.406,.,B,0.52,-0.01,8.037,8.037,92.05,HOA,-1.66867,0.520039,0.011045,0.343262 kka2_1:1_E262F,kka2_1:1_262,Kka2,kka2_1:1,P00552,0.343306,NO,262,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-0.829,-4.344,3.515,,0.059,G,A,1.04,-0.18,0.837,,42.42,AAH,-0.816,0.520039,0.0191586,0.343306 kka2_1:1_L93I,kka2_1:1_93,Kka2,kka2_1:1,P00552,0.343339,NO,93,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.815,-3.008,2.193,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.520039,0.00131498,0.343339 kka2_1:1_A150N,kka2_1:1_150,Kka2,kka2_1:1,P00552,0.343351,NO,150,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.949,-3.852,2.903,,0.544,T,A,0.46,1.34,2.333,,63.26,AHO,-1.272,0.520039,0.0045009,0.343351 Pab1_I157G,Pab1_157,Pab1,Pab1,P04147,0.343373,NO,157,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.623,-3.565,1.942,,,,,,,1.439,,79.72,BHH,-1.28667,0.175299,0.0018103,0.343373 beta-lactamase_39_G240I,beta-lactamase_39_240,TEM-1,beta-lactamase_39,P62593,0.343384,NO,240,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.0495842,0.00591201,0.343384 beta-lactamase_R59D,beta-lactamase_59,TEM-1,beta-lactamase,P62593,0.343391,NO,59,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.345,-3.634,2.289,5.49837,0.329,S,L,0.68,-0.09,1.806,,73.08,HBO,-2.24267,0.221079,0.00318082,0.343391 beta-lactamase_156_G76D,beta-lactamase_156_76,TEM-1,beta-lactamase_156,P62593,0.343392,NO,76,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.189,-3.614,2.425,,,H,A,0.29,-0.67,3.059,,67.83,OOH,-1.22267,0.111618,0.00476637,0.343392 kka2_1:4_S32N,kka2_1:4_32,Kka2,kka2_1:4,P00552,0.343448,NO,32,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-0.804,-3.251,2.447,,0.768,S,b,0.27,3.75,,,,OPA,-1.74533,0.168804,0.00149998,0.343448 beta-lactamase_I243N,beta-lactamase_243,TEM-1,beta-lactamase,P62593,0.34346,NO,243,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.532,-2.414,0.882,5.26886,,E,B,1.68,-1.24,2.289,,50,OHH,-1.46867,0.221079,0.00464034,0.34346 beta-lactamase_625_T131R,beta-lactamase_625_131,TEM-1,beta-lactamase_625,P62593,0.343525,NO,131,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.328,-2.888,1.56,,,H,A,0.22,-0.69,2.031,,67.48,PPH,-1.00867,0.213352,0.00345886,0.343525 kka2_1:2_W15N,kka2_1:2_15,Kka2,kka2_1:2,P00552,0.343627,NO,15,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-1.392,-4.342,2.95,,0.01,G,A,0.47,0.15,2.586,,52.27,HHH,-2.10533,0.295029,0.00585505,0.343627 beta-lactamase_2500_T187H,beta-lactamase_2500_187,TEM-1,beta-lactamase_2500,P62593,0.343709,NO,187,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.401,-4.688,3.287,,0.007,H,A,0.22,-1.19,3.91,,67.48,PPH,-1.69633,0.361275,0.00491782,0.343709 kka2_1:4_L123P,kka2_1:4_123,Kka2,kka2_1:4,P00552,0.34371,NO,123,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.888,-4.155,3.267,,0.007,H,A,0.55,-0.4,1.447,,48.86,BHB,-1.301,0.168804,0.00325188,0.34371 beta-lactamase_I256G,beta-lactamase_256,TEM-1,beta-lactamase,P62593,0.343807,NO,256,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.621,-3.804,2.183,5.3196,,E,B,1,-0.84,1.615,,73.08,BHH,-1.80667,0.221079,0.00710634,0.343807 beta-lactamase_156_T107P,beta-lactamase_156_107,TEM-1,beta-lactamase_156,P62593,0.343809,NO,107,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.117,-3.706,2.589,,,G,A,0.22,-0.06,0.341,,67.83,HPA,-1.265,0.111618,0.00239347,0.343809 beta-lactamase_G239M,beta-lactamase_239,TEM-1,beta-lactamase,P62593,0.34387,NO,239,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.819,-4.873,4.054,4.85529,0.115,T,l,0.77,-0.62,1.817,,42.31,BOP,-1.45267,0.221079,0.00213852,0.34387 kka2_1:2_D250R,kka2_1:2_250,Kka2,kka2_1:2,P00552,0.343904,NO,250,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.015,-3.871,2.856,,0.274,.,b,0.75,-0.46,3.796,,51.89,OAP,-1.83933,0.295029,0.0177103,0.343904 kka2_1:8_S32P,kka2_1:8_32,Kka2,kka2_1:8,P00552,0.343936,NO,32,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-0.804,-3.683,2.879,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.100394,0.00149998,0.343936 kka2_1:8_S32P,kka2_1:8_32,Kka2,kka2_1:8,P00552,0.343936,NO,32,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-0.804,-3.683,2.879,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.100394,0.00149998,0.343936 kka2_1:2_L223V,kka2_1:2_223,Kka2,kka2_1:2,P00552,0.343982,NO,223,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.861,-2.827,1.966,,,H,A,0.55,-1.24,0.266,,50,HHH,-0.854333,0.295029,0.00253574,0.343982 kka2_1:8_V97F,kka2_1:8_97,Kka2,kka2_1:8,P00552,0.344017,NO,97,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.453,-3.895,2.442,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.100394,0.00737869,0.344017 kka2_1:8_V97F,kka2_1:8_97,Kka2,kka2_1:8,P00552,0.344017,NO,97,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.453,-3.895,2.442,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.100394,0.00737869,0.344017 kka2_1:4_D261M,kka2_1:4_261,Kka2,kka2_1:4,P00552,0.344043,NO,261,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.708,-4.958,4.25,,0.146,G,A,0.75,-0.33,,,,HAA,-0.759333,0.168804,0.0224846,0.344043 kka2_1:1_P109Y,kka2_1:1_109,Kka2,kka2_1:1,P00552,0.344074,NO,109,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.412,-4.295,2.883,,0.376,H,A,0.52,-1.25,18.506,18.506,65.53,HOH,-1.84567,0.520039,0.0070929,0.344074 kka2_1:8_I207G,kka2_1:8_207,Kka2,kka2_1:8,P00552,0.344179,NO,207,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.175,-3.853,2.678,,0.293,,B,1.52,-1.12,1.306,,56.06,HHA,-1.07733,0.100394,0.00611824,0.344179 kka2_1:8_I207G,kka2_1:8_207,Kka2,kka2_1:8,P00552,0.344179,NO,207,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.175,-3.853,2.678,,0.293,,B,1.52,-1.12,1.306,,56.06,HHA,-1.07733,0.100394,0.00611824,0.344179 kka2_1:1_Y257M,kka2_1:1_257,Kka2,kka2_1:1,P00552,0.344204,NO,257,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-1.064,-4.488,3.424,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.520039,0.0148191,0.344204 beta-lactamase_2500_G240F,beta-lactamase_2500_240,TEM-1,beta-lactamase_2500,P62593,0.34422,NO,240,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.361275,0.00591201,0.34422 PSD95pdz3_L323G,PSD95pdz3_323,PSD95pdz3,PSD95pdz3,P31016,0.344237,NO,323,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.347,-3.49,2.143,5.12397,,,,,13.8825,,,,OHO,-1.121,0.0758425,0.00104644,0.344237 kka2_1:1_A224R,kka2_1:1_224,Kka2,kka2_1:1,P00552,0.344245,NO,224,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.977,-3.85,2.873,,,H,A,0.46,-1.26,1.725,,63.64,HHP,-1.41033,0.520039,0.00352047,0.344245 kka2_1:2_L184S,kka2_1:2_184,Kka2,kka2_1:2,P00552,0.344262,NO,184,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.496,-3.717,2.221,,0.489,E,B,0.55,-0.06,14.044,14.044,63.26,AHH,-1.24833,0.295029,0.00518742,0.344262 kka2_1:1_L184S,kka2_1:1_184,Kka2,kka2_1:1,P00552,0.344268,NO,184,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.496,-3.717,2.221,,0.489,E,B,0.55,-0.06,19.127,19.127,63.26,AHH,-1.24833,0.520039,0.00518742,0.344268 kka2_1:2_D208W,kka2_1:2_208,Kka2,kka2_1:2,P00552,0.344273,NO,208,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.708,-5.576,4.868,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.295029,0.00212588,0.344273 kka2_1:1_L158D,kka2_1:1_158,Kka2,kka2_1:1,P00552,0.344294,NO,158,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.947,-4.014,2.067,,0.095,.,B,0.55,0.77,7.588,,63.64,AHA,-1.25333,0.520039,0.00529068,0.344294 kka2_1:1_L193V,kka2_1:1_193,Kka2,kka2_1:1,P00552,0.344335,NO,193,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.983,-3.044,2.061,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.520039,0.00480179,0.344335 kka2_1:1_V84K,kka2_1:1_84,Kka2,kka2_1:1,P00552,0.344359,NO,84,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-2.279,-3.653,1.374,,0.258,E,B,0.44,1.03,3.484,,71.59,HHP,-2.337,0.520039,0.00724019,0.344359 gb1_V265K,gb1_265,gb1,gb1,P06654,0.344361,NO,265,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.843,-3.486,1.643,,,,,,,0.402,,11.83,OHA,-1.64567,0.177985,0.00360613,0.344361 kka2_1:1_Y22W,kka2_1:1_22,Kka2,kka2_1:1,P00552,0.344376,NO,22,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-1.583,-4.944,3.361,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.520039,0.00598977,0.344376 beta-lactamase_2500_R91W,beta-lactamase_2500_91,TEM-1,beta-lactamase_2500,P62593,0.344389,NO,91,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.392,-5.388,3.996,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.361275,0.00380226,0.344389 kka2_1:8_I196G,kka2_1:8_196,Kka2,kka2_1:8,P00552,0.344421,NO,196,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-2.115,-3.858,1.743,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.100394,0.0107273,0.344421 kka2_1:8_I196G,kka2_1:8_196,Kka2,kka2_1:8,P00552,0.344421,NO,196,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-2.115,-3.858,1.743,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.100394,0.0107273,0.344421 kka2_1:8_S32Q,kka2_1:8_32,Kka2,kka2_1:8,P00552,0.344421,NO,32,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-0.804,-3.703,2.899,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.100394,0.00149998,0.344421 kka2_1:8_S32Q,kka2_1:8_32,Kka2,kka2_1:8,P00552,0.344421,NO,32,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-0.804,-3.703,2.899,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.100394,0.00149998,0.344421 PSD95pdz3_H372L,PSD95pdz3_372,PSD95pdz3,PSD95pdz3,P31016,0.344424,NO,372,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-1.627,-3.265,1.638,5.5607,,,,,17.008,,,,PBA,-1.63033,0.0758425,0.00040301,0.344424 kka2_1:1_E161M,kka2_1:1_161,Kka2,kka2_1:1,P00552,0.344442,NO,161,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.581,-4.788,3.207,,0.829,G,A,1.04,2.24,1.612,,92.05,AAB,-1.861,0.520039,0.00760103,0.344442 kka2_1:1_F256P,kka2_1:1_256,Kka2,kka2_1:1,P00552,0.344462,NO,256,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.49,-4.358,2.868,,,H,A,1.62,-0.78,2.354,,53.03,HHH,-1.423,0.520039,0.0132841,0.344462 beta-lactamase_625_A235P,beta-lactamase_625_235,TEM-1,beta-lactamase_625,P62593,0.344464,NO,235,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.266,-3.821,2.555,,0.32,E,B,0.46,-0.86,0.281,,50,OHO,-0.89,0.213352,0.00493474,0.344464 kka2_1:4_S32K,kka2_1:4_32,Kka2,kka2_1:4,P00552,0.344486,NO,32,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-0.804,-3.26,2.456,,0.768,S,b,0.27,3.75,,,,OPA,-1.74533,0.168804,0.00149998,0.344486 kka2_1:1_L184G,kka2_1:1_184,Kka2,kka2_1:1,P00552,0.344529,NO,184,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.496,-3.006,1.51,,0.489,E,B,0.55,-0.06,19.127,19.127,63.26,AHH,-1.24833,0.520039,0.00518742,0.344529 kka2_1:1_A108I,kka2_1:1_108,Kka2,kka2_1:1,P00552,0.34465,NO,108,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.061,-3.962,1.901,,0.243,.,B,0.46,-1.34,3.156,,71.59,HHO,-1.57033,0.520039,0.00751209,0.34465 kka2_1:1_A87P,kka2_1:1_87,Kka2,kka2_1:1,P00552,0.344715,NO,87,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.917,-2.939,1.022,,1.039,S,L,0.46,1.57,20.738,20.738,65.53,AHO,-1.822,0.520039,0.00791281,0.344715 kka2_1:1_I141F,kka2_1:1_141,Kka2,kka2_1:1,P00552,0.34473,NO,141,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.495,-3.83,2.335,,0.068,H,A,0.48,-0.01,7.546,7.546,92.05,BHA,-1.689,0.520039,0.00744745,0.34473 beta-lactamase_2500_G265K,beta-lactamase_2500_265,TEM-1,beta-lactamase_2500,P62593,0.344752,NO,265,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.361275,0.00811926,0.344752 kka2_1:4_A117H,kka2_1:4_117,Kka2,kka2_1:4,P00552,0.344759,NO,117,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.828,-4.772,3.944,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.168804,0.00282984,0.344759 kka2_1:4_V49R,kka2_1:4_49,Kka2,kka2_1:4,P00552,0.344788,NO,49,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.614,-4.154,2.54,,,E,B,0.44,-0.77,1.233,,64.39,HHB,-1.3,0.168804,0.00615685,0.344788 kka2_1:1_E235R,kka2_1:1_235,Kka2,kka2_1:1,P00552,0.344836,NO,235,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.955,-2.75,0.795,,0.631,H,A,1.52,0.12,8.521,,65.53,OAH,-2.07267,0.520039,0.0102806,0.344836 kka2_1:1_D190V,kka2_1:1_190,Kka2,kka2_1:1,P00552,0.34493,NO,190,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.708,-3.782,3.074,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.520039,0.00247989,0.34493 beta-lactamase_0_H110I,beta-lactamase_0_110,TEM-1,beta-lactamase_0,P62593,0.344984,NO,110,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-1.706,-4.048,2.342,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.0500837,0.00441499,0.344984 kka2_1:1_R145I,kka2_1:1_145,Kka2,kka2_1:1,P00552,0.345117,NO,145,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.804,-4.111,2.307,,0.346,H,A,1.2,1.23,23.699,23.699,63.64,HBP,-1.88033,0.520039,0.00846663,0.345117 beta-lactamase_2500_W208C,beta-lactamase_2500_208,TEM-1,beta-lactamase_2500,P62593,0.345166,NO,208,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-0.818,-4.862,4.044,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.361275,0.00126609,0.345166 beta-lactamase_625_R159D,beta-lactamase_625_159,TEM-1,beta-lactamase_625,P62593,0.345208,NO,159,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-0.94,-3.691,2.751,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.213352,0.00108472,0.345208 beta-lactamase_2500_L79T,beta-lactamase_2500_79,TEM-1,beta-lactamase_2500,P62593,0.345212,NO,79,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.842,-3.447,2.605,,0.007,H,A,0.55,-0.16,0.823,,50.35,HHP,-1.44333,0.361275,0.000947397,0.345212 kka2_1:1_S54W,kka2_1:1_54,Kka2,kka2_1:1,P00552,0.345231,NO,54,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.471,-5.559,3.088,,0.408,S,b,0.27,1.01,6.085,,71.59,HPO,-2.259,0.520039,0.00782867,0.345231 kka2_1:4_M197G,kka2_1:4_197,Kka2,kka2_1:4,P00552,0.345234,NO,197,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.707,-3.845,2.138,,0.121,E,B,0.55,-1.19,0.415,,65.53,HHH,-1.847,0.168804,0.00921295,0.345234 beta-lactamase_625_I258T,beta-lactamase_625_258,TEM-1,beta-lactamase_625,P62593,0.345328,NO,258,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.213352,0.007931,0.345328 kka2_1:1_L193K,kka2_1:1_193,Kka2,kka2_1:1,P00552,0.345341,NO,193,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.983,-3.668,2.685,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.520039,0.00480179,0.345341 kka2_1:2_C192Y,kka2_1:2_192,Kka2,kka2_1:2,P00552,0.345342,NO,192,C,Y,CY,Special,Hydrophobic,5.07,5.66,0.59,194,121,181,60,108.5,193.6,85.1,-1.067,-2.934,1.867,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.295029,0.00485428,0.345342 kka2_1:1_L170C,kka2_1:1_170,Kka2,kka2_1:1,P00552,0.345348,NO,170,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.28,-4.755,3.475,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.520039,0.00730791,0.345348 kka2_1:8_E262F,kka2_1:8_262,Kka2,kka2_1:8,P00552,0.345387,NO,262,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-0.829,-4.344,3.515,,0.059,G,A,1.52,-0.18,0.837,,42.42,AAH,-0.816,0.100394,0.0191586,0.345387 kka2_1:8_E262F,kka2_1:8_262,Kka2,kka2_1:8,P00552,0.345387,NO,262,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-0.829,-4.344,3.515,,0.059,G,A,1.52,-0.18,0.837,,42.42,AAH,-0.816,0.100394,0.0191586,0.345387 beta-lactamase_S240L,beta-lactamase_240,TEM-1,beta-lactamase,P62593,0.345494,NO,240,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.537,-3.403,1.866,4.75024,,,B,0.74,-0.74,0.357,,65.38,OPB,-1.263,0.221079,0.00591201,0.345494 kka2_1:8_R211F,kka2_1:8_211,Kka2,kka2_1:8,P00552,0.345508,NO,211,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-0.899,-4.206,3.307,,0.12,T,a,0.16,-0.39,0.615,,49.62,OBH,-0.966,0.100394,0.00204888,0.345508 kka2_1:8_R211F,kka2_1:8_211,Kka2,kka2_1:8,P00552,0.345508,NO,211,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-0.899,-4.206,3.307,,0.12,T,a,0.16,-0.39,0.615,,49.62,OBH,-0.966,0.100394,0.00204888,0.345508 kka2_1:8_S204W,kka2_1:8_204,Kka2,kka2_1:8,P00552,0.345508,NO,204,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.353,-5.392,4.039,,0.144,E,A,0.27,-1.2,0.368,,65.53,HPO,-0.953333,0.100394,0.00881794,0.345508 kka2_1:8_S204W,kka2_1:8_204,Kka2,kka2_1:8,P00552,0.345508,NO,204,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.353,-5.392,4.039,,0.144,E,A,0.27,-1.2,0.368,,65.53,HPO,-0.953333,0.100394,0.00881794,0.345508 kka2_1:4_D82I,kka2_1:4_82,Kka2,kka2_1:4,P00552,0.345554,NO,82,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.946,-4.04,2.094,,0.341,E,b,0.75,0.52,11.923,11.923,63.64,HAH,-1.98,0.168804,0.00637516,0.345554 beta-lactamase_39_A185D,beta-lactamase_39_185,TEM-1,beta-lactamase_39,P62593,0.345596,NO,185,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.406,-3.867,2.461,,,H,A,0.46,-1.02,2.68,,65.03,HHP,-1.84033,0.0495842,0.00467449,0.345596 beta-lactamase_39_W227D,beta-lactamase_39_227,TEM-1,beta-lactamase_39,P62593,0.345598,NO,227,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-0.982,-4.076,3.094,,0.272,,B,0.47,-0.29,1.37,,74.48,OHH,-1.595,0.0495842,0.00226019,0.345598 kka2_1:1_L232Q,kka2_1:1_232,Kka2,kka2_1:1,P00552,0.345599,NO,232,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.514,-4.349,2.835,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.520039,0.00800103,0.345599 beta-lactamase_39_T158E,beta-lactamase_39_158,TEM-1,beta-lactamase_39,P62593,0.345626,NO,158,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.116,-3.449,2.333,,0.036,,B,0.22,-0.85,2.755,,69.58,HPB,-1.269,0.0495842,0.00341825,0.345626 kka2_1:2_L102S,kka2_1:2_102,Kka2,kka2_1:2,P00552,0.345626,NO,102,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.804,-3.637,2.833,,,T,A,1.59,-1.17,4.258,,42.42,AHH,-1.398,0.295029,0.00201332,0.345626 kka2_1:1_H135L,kka2_1:1_135,Kka2,kka2_1:1,P00552,0.345656,NO,135,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-1.331,-2.788,1.457,,0.071,.,a,0.17,0.65,3.574,,53.03,ABP,-1.77367,0.520039,0.00532566,0.345656 kka2_1:1_H135V,kka2_1:1_135,Kka2,kka2_1:1,P00552,0.345656,NO,135,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-1.331,-3.678,2.347,,0.071,.,a,0.17,0.65,3.574,,53.03,ABP,-1.77367,0.520039,0.00532566,0.345656 kka2_1:4_R253D,kka2_1:4_253,Kka2,kka2_1:4,P00552,0.345676,NO,253,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.356,-3.762,2.406,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.168804,0.0144195,0.345676 kka2_1:4_F256E,kka2_1:4_256,Kka2,kka2_1:4,P00552,0.345705,NO,256,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.49,-3.921,2.431,,,H,A,0.58,-0.78,1.653,,53.03,HHH,-1.423,0.168804,0.0132841,0.345705 beta-lactamase_2500_R176T,beta-lactamase_2500_176,TEM-1,beta-lactamase_2500,P62593,0.345717,NO,176,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-0.863,-3.421,2.558,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.361275,0.00105554,0.345717 kka2_1:1_D134L,kka2_1:1_134,Kka2,kka2_1:1,P00552,0.34575,NO,134,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.969,-2.811,1.842,,0.421,B,B,0.75,0.31,2.329,,49.62,HAB,-1.057,0.520039,0.00270812,0.34575 beta-lactamase_625_V31F,beta-lactamase_625_31,TEM-1,beta-lactamase_625,P62593,0.345795,NO,31,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.822,-2.736,0.914,,,H,A,0.44,-0.46,2.576,,73.78,BHB,-2.03767,0.213352,0.00478065,0.345795 kka2_1:2_E182K,kka2_1:2_182,Kka2,kka2_1:2,P00552,0.345809,NO,182,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.516,-3.472,1.956,,0.326,,B,1.52,0.75,14.547,14.547,65.53,OAA,-1.806,0.295029,0.00641548,0.345809 beta-lactamase_2500_I45G,beta-lactamase_2500_45,TEM-1,beta-lactamase_2500,P62593,0.34582,NO,45,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-2.421,-3.565,1.144,,,E,B,0.48,-0.3,3.793,,77.62,HHA,-2.30267,0.361275,0.00452842,0.34582 kka2_1:1_L152D,kka2_1:1_152,Kka2,kka2_1:1,P00552,0.345839,NO,152,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.521,-3.958,2.437,,0.547,.,A,0.55,1.36,1.589,,63.64,OHH,-1.162,0.520039,0.00674868,0.345839 kka2_1:1_I115N,kka2_1:1_115,Kka2,kka2_1:1,P00552,0.345847,NO,115,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.606,-4.227,2.621,,0.105,H,A,0.48,-1.18,0.878,,65.53,PHH,-2.205,0.520039,0.00836567,0.345847 beta-lactamase_0_A170K,beta-lactamase_0_170,TEM-1,beta-lactamase_0,P62593,0.345849,NO,170,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.237,-3.643,2.406,,0.126,,L,0.46,-0.35,2.427,,64.69,AHH,-1.63267,0.0500837,0.00431903,0.345849 beta-lactamase_625_Y95R,beta-lactamase_625_95,TEM-1,beta-lactamase_625,P62593,0.34591,NO,95,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-1.715,-4.186,2.471,,0.122,,b,0.21,-0.37,3.355,,77.62,BHP,-2.16167,0.213352,0.00479449,0.34591 kka2_1:1_I254E,kka2_1:1_254,Kka2,kka2_1:1,P00552,0.345959,NO,254,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.933,-3.931,1.998,,0.135,H,A,1.52,-0.6,1.859,,71.59,BHH,-1.668,0.520039,0.0132375,0.345959 kka2_1:1_C209Y,kka2_1:1_209,Kka2,kka2_1:1,P00552,0.345964,NO,209,C,Y,CY,Special,Hydrophobic,5.07,5.66,0.59,194,121,181,60,108.5,193.6,85.1,-0.906,-4.189,3.283,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.520039,0.00260862,0.345964 kka2_1:4_H188Y,kka2_1:4_188,Kka2,kka2_1:4,P00552,0.345999,NO,188,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-0.913,-3.365,2.452,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.168804,0.00273139,0.345999 beta-lactamase_2500_I140N,beta-lactamase_2500_140,TEM-1,beta-lactamase_2500,P62593,0.34605,NO,140,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.733,-4.2,2.467,,0.128,H,A,0.48,0.41,1.628,,73.08,PHO,-1.48733,0.361275,0.00597777,0.34605 kka2_1:1_A117H,kka2_1:1_117,Kka2,kka2_1:1,P00552,0.346056,NO,117,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.828,-4.772,3.944,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.520039,0.00282984,0.346056 kka2_1:8_F240G,kka2_1:8_240,Kka2,kka2_1:8,P00552,0.346111,NO,240,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-0.911,-3.675,2.764,,,H,A,1.62,-1.21,0.697,,50.38,BHH,-1.67267,0.100394,0.00552543,0.346111 kka2_1:8_F240G,kka2_1:8_240,Kka2,kka2_1:8,P00552,0.346111,NO,240,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-0.911,-3.675,2.764,,,H,A,1.62,-1.21,0.697,,50.38,BHH,-1.67267,0.100394,0.00552543,0.346111 kka2_1:1_G21N,kka2_1:1_21,Kka2,kka2_1:1,P00552,0.346163,NO,21,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.368,-3.58,2.212,,0.586,T,l,0.29,-0.75,10.291,10.291,71.59,HOH,-2.10167,0.520039,0.00709648,0.346163 kka2_1:4_T51D,kka2_1:4_51,Kka2,kka2_1:4,P00552,0.346168,NO,51,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.199,-3.85,1.651,,0.05,E,B,0.82,-0.05,13.165,13.165,63.64,BPA,-1.76767,0.168804,0.00628861,0.346168 beta-lactamase_G242T,beta-lactamase_242,TEM-1,beta-lactamase,P62593,0.346202,NO,242,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.319,-3.42,2.101,4.68003,,E,B,0.87,-1.05,1.079,,50,BOH,-1.428,0.221079,0.00452879,0.346202 kka2_1:1_R217H,kka2_1:1_217,Kka2,kka2_1:1,P00552,0.346224,NO,217,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.158,-4.518,3.36,,0.252,T,A,1.2,-0.59,0.381,,52.27,ABH,-1.127,0.520039,0.0047191,0.346224 beta-lactamase_L167K,beta-lactamase_167,TEM-1,beta-lactamase,P62593,0.34625,NO,167,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.138,-3.594,2.456,5.13111,0.015,G,A,0.08,-0.63,0.4,,64.69,AHP,-1.30767,0.221079,0.00303566,0.34625 kka2_1:1_G30P,kka2_1:1_30,Kka2,kka2_1:1,P00552,0.346253,NO,30,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.596,-3.908,3.312,,0.54,S,g,0.29,3.76,,,,HOO,-1.51133,0.520039,0.00159208,0.346253 kka2_1:1_A64K,kka2_1:1_64,Kka2,kka2_1:1,P00552,0.346255,NO,64,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.496,-3.777,2.281,,0.039,H,A,0.46,-0.57,1.175,,56.06,AHH,-1.334,0.520039,0.00705578,0.346255 kka2_1:4_W236Q,kka2_1:4_236,Kka2,kka2_1:4,P00552,0.346398,NO,236,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-1.363,-4.284,2.921,,0.303,H,A,0.47,-0.76,2.277,,48.48,AHH,-1.81267,0.168804,0.0088796,0.346398 kka2_1:1_V97W,kka2_1:1_97,Kka2,kka2_1:1,P00552,0.346441,NO,97,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.453,-5.36,3.907,,0.083,,B,1.48,-0.83,13.576,13.576,53.03,AHO,-1.85067,0.520039,0.00737869,0.346441 beta-lactamase_156_Y44E,beta-lactamase_156_44,TEM-1,beta-lactamase_156,P62593,0.346453,NO,44,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-2.547,-3.866,1.319,,,E,B,0.21,-0.45,2.184,,73.78,OHH,-1.86267,0.111618,0.00426364,0.346453 PSD95pdz3_A347D,PSD95pdz3_347,PSD95pdz3,PSD95pdz3,P31016,0.34648,NO,347,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.307,-3.375,2.068,4.89689,,,,,15.176,,,,OHA,-1.269,0.0758425,0.00074525,0.34648 kka2_1:1_A172L,kka2_1:1_172,Kka2,kka2_1:1,P00552,0.346565,NO,172,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.757,-2.996,1.239,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.520039,0.0079265,0.346565 E1_Ubiquitin_I44K,E1_Ubiquitin_44,Uba1,E1_Ubiquitin,P0CG63,0.346596,NO,44,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.432,-3.671,2.239,,,E,B,0.27,-1.17,4.57,,78.74,HHH,-1.25633,0.18783,0.00209731,0.346596 beta-lactamase_R255N,beta-lactamase_255,TEM-1,beta-lactamase,P62593,0.346599,NO,255,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.266,-4.059,1.793,5.55882,0.141,E,B,0.68,0.38,1.199,,63.99,PBH,-2.00433,0.221079,0.00499612,0.346599 beta-lactamase_2500_L219R,beta-lactamase_2500_219,TEM-1,beta-lactamase_2500,P62593,0.3466,NO,219,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.313,-4.126,2.813,,,I,A,0.55,-0.51,35.994,35.994,74.48,HHB,-1.21533,0.361275,0.00664345,0.3466 kka2_1:4_A78V,kka2_1:4_78,Kka2,kka2_1:4,P00552,0.346622,NO,78,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.744,-3.452,1.708,,0.078,.,B,0.46,-0.53,0.594,,56.06,OHH,-1.863,0.168804,0.00457299,0.346622 kka2_1:1_G99H,kka2_1:1_99,Kka2,kka2_1:1,P00552,0.346627,NO,99,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.596,-4.708,4.112,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.520039,0.00186055,0.346627 beta-lactamase_156_F64A,beta-lactamase_156_64,TEM-1,beta-lactamase_156,P62593,0.34663,NO,64,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-0.841,-3.303,2.462,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.111618,0.000947691,0.34663 kka2_1:2_W91I,kka2_1:2_91,Kka2,kka2_1:2,P00552,0.346691,NO,91,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-1.178,-3.942,2.764,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.295029,0.00358653,0.346691 Ubiquitin_E34P,Ubiquitin_34,Uba1,Ubiquitin,P0CG48,0.346774,NO,34,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.294,-3.772,2.478,5.02178,0.406,H,A,1.62,0.6,1.295,,35.62,BAO,-1.24933,0.205827,0.000686048,0.346774 Ubiquitin_F4N,Ubiquitin_4,Uba1,Ubiquitin,P0CG48,0.346774,NO,4,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.534,-3.814,2.28,4.77459,0.059,E,B,,-0.46,,,,HHH,-1.504,0.205827,0.000805043,0.346774 Ubiquitin_K27N,Ubiquitin_27,Uba1,Ubiquitin,P0CG48,0.346774,NO,27,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.064,-3.448,2.384,4.77438,0.086,H,A,2.89,-0.74,2.662,,27.01,HBH,-1.42667,0.205827,0.000767556,0.346774 Ubiquitin_L71I,Ubiquitin_71,Uba1,Ubiquitin,P0CG48,0.346774,NO,71,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.647,-2.593,0.946,5.02588,0.591,E,B,2.89,-0.69,4.365,,34.31,HHB,-1.85167,0.205827,0.000949314,0.346774 Ubiquitin_T7R,Ubiquitin_7,Uba1,Ubiquitin,P0CG48,0.346774,NO,7,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.415,-3.846,2.431,4.954,0.094,E,B,0.43,-0.78,0.805,,21.31,BPH,-1.41033,0.205827,0.000647855,0.346774 kka2_1:2_W91H,kka2_1:2_91,Kka2,kka2_1:2,P00552,0.346811,NO,91,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-1.178,-4.573,3.395,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.295029,0.00358653,0.346811 beta-lactamase_2500_I45E,beta-lactamase_2500_45,TEM-1,beta-lactamase_2500,P62593,0.34688,NO,45,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-2.421,-3.737,1.316,,,E,B,0.48,-0.3,3.793,,77.62,HHA,-2.30267,0.361275,0.00452842,0.34688 kka2_1:1_L103G,kka2_1:1_103,Kka2,kka2_1:1,P00552,0.346889,NO,103,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-2.362,-2.706,0.344,,0.394,T,A,0.55,-0.99,4.121,,63.64,HHP,-1.534,0.520039,0.00574792,0.346889 beta-lactamase_2500_S241V,beta-lactamase_2500_241,TEM-1,beta-lactamase_2500,P62593,0.347025,NO,241,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.361275,0.00452736,0.347025 PSD95pdz3_G329N,PSD95pdz3_329,PSD95pdz3,PSD95pdz3,P31016,0.347041,NO,329,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.008,-3.13,2.122,4.7671,,,,,19.7075,,,,HOO,-1.16033,0.0758425,0.000974577,0.347041 kka2_1:2_R38N,kka2_1:2_38,Kka2,kka2_1:2,P00552,0.347045,NO,38,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.207,-3.763,2.556,,0.355,E,B,1.2,-1.13,6.872,6.872,52.27,HBH,-1.28567,0.295029,0.00372499,0.347045 beta-lactamase_L205E,beta-lactamase_205,TEM-1,beta-lactamase,P62593,0.347065,NO,205,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.922,-3.908,2.986,5.67023,,H,A,1.3,-0.46,0.678,,42.31,PHH,-1.57767,0.221079,0.00255802,0.347065 kka2_1:4_G88Y,kka2_1:4_88,Kka2,kka2_1:4,P00552,0.347081,NO,88,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.689,-4.408,2.719,,0.54,S,l,0.29,1.51,7.899,,65.53,HOB,-1.718,0.168804,0.00685559,0.347081 kka2_1:1_E182D,kka2_1:1_182,Kka2,kka2_1:1,P00552,0.347118,NO,182,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.516,-2.787,1.271,,0.326,,B,1.52,0.75,14.547,14.547,65.53,OAA,-1.806,0.520039,0.00641548,0.347118 kka2_1:4_L39Q,kka2_1:4_39,Kka2,kka2_1:4,P00552,0.34718,NO,39,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.223,-4.313,3.09,,,E,B,0.55,-1.21,1.998,,71.59,BHP,-1.69167,0.168804,0.00493618,0.34718 beta-lactamase_0_S104F,beta-lactamase_0_104,TEM-1,beta-lactamase_0,P62593,0.347184,NO,104,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.015,-4.127,3.112,,0.04,,b,0.27,0.57,1.148,,63.29,HPO,-1.05267,0.0500837,0.00218083,0.347184 kka2_1:1_A64M,kka2_1:1_64,Kka2,kka2_1:1,P00552,0.347261,NO,64,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.496,-4.439,2.943,,0.039,H,A,0.46,-0.57,1.175,,56.06,AHH,-1.334,0.520039,0.00705578,0.347261 kka2_1:4_S32Q,kka2_1:4_32,Kka2,kka2_1:4,P00552,0.347348,NO,32,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-0.804,-3.703,2.899,,0.768,S,b,0.27,3.75,,,,OPA,-1.74533,0.168804,0.00149998,0.347348 kka2_1:1_A237L,kka2_1:1_237,Kka2,kka2_1:1,P00552,0.347404,NO,237,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.12,-2.076,-0.044,,0.068,H,A,0.46,-0.71,2.369,,92.05,HHA,-2.10433,0.520039,0.012257,0.347404 kka2_1:1_F264P,kka2_1:1_264,Kka2,kka2_1:1,P00552,0.347538,NO,264,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.02,-4.363,3.343,,0.296,.,?,0.58,0.02,2.303,,71.59,HHNA,-0.9655,0.520039,,0.347538 beta-lactamase_625_F64I,beta-lactamase_625_64,TEM-1,beta-lactamase_625,P62593,0.347566,NO,64,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-0.841,-3.335,2.494,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.213352,0.000947691,0.347566 kka2_1:2_D208K,kka2_1:2_208,Kka2,kka2_1:2,P00552,0.347585,NO,208,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.708,-3.485,2.777,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.295029,0.00212588,0.347585 beta-lactamase_2500_I258Y,beta-lactamase_2500_258,TEM-1,beta-lactamase_2500,P62593,0.347613,NO,258,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.361275,0.007931,0.347613 kka2_1:4_S204E,kka2_1:4_204,Kka2,kka2_1:4,P00552,0.347669,NO,204,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.353,-3.494,2.141,,0.144,E,A,0.27,-1.2,2.442,,65.53,HPO,-0.953333,0.168804,0.00881794,0.347669 kka2_1:8_A191D,kka2_1:8_191,Kka2,kka2_1:8,P00552,0.347672,NO,191,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.831,-3.72,2.889,,,,b,1.04,-0.94,1.306,,50,AHO,-0.868667,0.100394,0.00338807,0.347672 kka2_1:8_A191D,kka2_1:8_191,Kka2,kka2_1:8,P00552,0.347672,NO,191,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.831,-3.72,2.889,,,,b,1.04,-0.94,1.306,,50,AHO,-0.868667,0.100394,0.00338807,0.347672 kka2_1:1_F133K,kka2_1:1_133,Kka2,kka2_1:1,P00552,0.347772,NO,133,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-0.871,-3.933,3.062,,0.178,.,B,0.58,0.43,1.999,,42.42,OHA,-0.871667,0.520039,0.00182168,0.347772 kka2_1:1_G233T,kka2_1:1_233,Kka2,kka2_1:1,P00552,0.347908,NO,233,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.748,-3.674,2.926,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.520039,0.00232366,0.347908 beta-lactamase_2500_S104V,beta-lactamase_2500_104,TEM-1,beta-lactamase_2500,P62593,0.347912,NO,104,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.015,-3.487,2.472,,0.04,,b,0.27,0.57,1.133,,63.29,HPO,-1.05267,0.361275,0.00218083,0.347912 kka2_1:1_L123I,kka2_1:1_123,Kka2,kka2_1:1,P00552,0.347959,NO,123,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.888,-2.453,1.565,,0.007,H,A,0.55,-0.4,1.447,,48.86,BHB,-1.301,0.520039,0.00325188,0.347959 kka2_1:2_G43W,kka2_1:2_43,Kka2,kka2_1:2,P00552,0.348016,NO,43,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.587,-5.439,3.852,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.295029,0.0071925,0.348016 kka2_1:1_W69H,kka2_1:1_69,Kka2,kka2_1:1,P00552,0.348017,NO,69,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-0.859,-4.594,3.735,,0.164,H,A,0.47,0.15,5.074,,38.64,PHH,-1.49967,0.520039,0.0012874,0.348017 kka2_1:1_A237T,kka2_1:1_237,Kka2,kka2_1:1,P00552,0.348054,NO,237,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.12,-2.777,0.657,,0.068,H,A,0.46,-0.71,2.369,,92.05,HHA,-2.10433,0.520039,0.012257,0.348054 kka2_1:1_E111T,kka2_1:1_111,Kka2,kka2_1:1,P00552,0.348087,NO,111,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.28,-2.755,0.475,,0.155,H,A,1.52,-1.14,15.716,15.716,65.53,HAB,-2.27833,0.520039,0.00746789,0.348087 beta-lactamase_156_L284D,beta-lactamase_156_284,TEM-1,beta-lactamase_156,P62593,0.34809,NO,284,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.111618,0.0686156,0.34809 beta-lactamase_625_A246W,beta-lactamase_625_246,TEM-1,beta-lactamase_625,P62593,0.348102,NO,246,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.121,-5.267,3.146,,0.01,E,B,0.46,-1.01,1.201,,73.78,HHH,-1.55633,0.213352,0.00569458,0.348102 beta-lactamase_2500_L248P,beta-lactamase_2500_248,TEM-1,beta-lactamase_2500,P62593,0.348132,NO,248,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.361275,0.00428493,0.348132 beta-lactamase_625_W208V,beta-lactamase_625_208,TEM-1,beta-lactamase_625,P62593,0.348149,NO,208,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-0.818,-3.754,2.936,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.213352,0.00126609,0.348149 kka2_1:4_R147P,kka2_1:4_147,Kka2,kka2_1:4,P00552,0.348227,NO,147,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.123,-3.991,2.868,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.168804,0.00549168,0.348227 kka2_1:4_I228F,kka2_1:4_228,Kka2,kka2_1:4,P00552,0.34823,NO,228,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.142,-3.751,2.609,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.168804,0.00458834,0.34823 beta-lactamase_2500_I125A,beta-lactamase_2500_125,TEM-1,beta-lactamase_2500,P62593,0.348235,NO,125,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.441,-3.138,1.697,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.361275,0.00383964,0.348235 beta-lactamase_39_C121P,beta-lactamase_39_121,TEM-1,beta-lactamase_39,P62593,0.348261,NO,121,C,P,CP,Special,Special,5.07,6.3,1.23,169,121,115,-6,108.5,112.7,4.2,-0.953,-4.102,3.149,,,H,A,0.46,-0.81,7.644,,63.29,HOP,-1.46767,0.0495842,0.000744322,0.348261 beta-lactamase_2500_Q37P,beta-lactamase_2500_37,TEM-1,beta-lactamase_2500,P62593,0.348295,NO,37,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.134,-3.965,1.831,,0.613,H,A,0.64,1.98,1.318,,73.08,APH,-2.06967,0.361275,0.00425833,0.348295 kka2_1:1_G189T,kka2_1:1_189,Kka2,kka2_1:1,P00552,0.34833,NO,189,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.596,-3.675,3.079,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.520039,0.00253688,0.34833 kka2_1:1_Q27L,kka2_1:1_27,Kka2,kka2_1:1,P00552,0.348332,NO,27,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-1.659,-2.589,0.93,,0.608,.,A,0.64,0.71,0.521,,65.53,PPP,-1.90733,0.520039,0.00595365,0.348332 kka2_1:8_R66Q,kka2_1:8_66,Kka2,kka2_1:8,P00552,0.34839,NO,66,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-0.922,-3.512,2.59,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.100394,0.00161025,0.34839 kka2_1:8_R66Q,kka2_1:8_66,Kka2,kka2_1:8,P00552,0.34839,NO,66,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-0.922,-3.512,2.59,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.100394,0.00161025,0.34839 beta-lactamase_L205Q,beta-lactamase_205,TEM-1,beta-lactamase,P62593,0.348406,NO,205,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.922,-4.179,3.257,5.67023,,H,A,1.3,-0.46,0.678,,42.31,PHH,-1.57767,0.221079,0.00255802,0.348406 beta-lactamase_156_Y95E,beta-lactamase_156_95,TEM-1,beta-lactamase_156,P62593,0.348496,NO,95,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-1.715,-3.911,2.196,,0.122,,b,0.21,-0.37,2.341,,77.62,BHP,-2.16167,0.111618,0.00479449,0.348496 kka2_1:8_F203G,kka2_1:8_203,Kka2,kka2_1:8,P00552,0.34851,NO,203,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-0.911,-3.675,2.764,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.100394,0.00318738,0.34851 kka2_1:8_F203G,kka2_1:8_203,Kka2,kka2_1:8,P00552,0.34851,NO,203,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-0.911,-3.675,2.764,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.100394,0.00318738,0.34851 beta-lactamase_625_L74G,beta-lactamase_625_74,TEM-1,beta-lactamase_625,P62593,0.348512,NO,74,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.296,-3.477,2.181,,,H,A,0.55,-0.91,0.895,,50,HHO,-1.34933,0.213352,0.00493255,0.348512 kka2_1:1_H188M,kka2_1:1_188,Kka2,kka2_1:1,P00552,0.348564,NO,188,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-0.913,-4.701,3.788,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.520039,0.00273139,0.348564 kka2_1:4_A224D,kka2_1:4_224,Kka2,kka2_1:4,P00552,0.348594,NO,224,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.977,-3.763,2.786,,,H,A,0.46,-1.26,0.93,,63.64,HHP,-1.41033,0.168804,0.00352047,0.348594 kka2_1:2_V198I,kka2_1:2_198,Kka2,kka2_1:2,P00552,0.3486,NO,198,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.719,-3.396,1.677,,0.05,E,B,1.48,-0.95,1.074,,56.06,HHA,-1.88667,0.295029,0.00835002,0.3486 beta-lactamase_625_S233C,beta-lactamase_625_233,TEM-1,beta-lactamase_625,P62593,0.348624,NO,233,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.886,-4.789,2.903,,0.016,E,B,0.27,-1.01,1.773,,77.62,BPO,-1.17267,0.213352,0.00311415,0.348624 kka2_1:2_E262I,kka2_1:2_262,Kka2,kka2_1:2,P00552,0.348633,NO,262,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-0.829,-4.062,3.233,,0.059,G,A,1.04,-0.18,2.383,,42.42,AAH,-0.816,0.295029,0.0191586,0.348633 beta-lactamase_2500_A235R,beta-lactamase_2500_235,TEM-1,beta-lactamase_2500,P62593,0.348698,NO,235,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.266,-3.887,2.621,,0.32,E,B,0.46,-0.86,0.891,,50,OHO,-0.89,0.361275,0.00493474,0.348698 beta-lactamase_625_D174L,beta-lactamase_625_174,TEM-1,beta-lactamase_625,P62593,0.348711,NO,174,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.738,-3.808,3.07,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.213352,0.00125633,0.348711 beta-lactamase_156_G142I,beta-lactamase_156_142,TEM-1,beta-lactamase_156,P62593,0.348737,NO,142,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.707,-4.199,3.492,,0.034,,p,0.29,-0.64,0.325,,64.69,OOO,-0.834,0.111618,0.00060149,0.348737 kka2_1:2_R202P,kka2_1:2_202,Kka2,kka2_1:2,P00552,0.348833,NO,202,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.761,-4.079,2.318,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.295029,0.00696498,0.348833 kka2_1:8_F256P,kka2_1:8_256,Kka2,kka2_1:8,P00552,0.348868,NO,256,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.49,-4.358,2.868,,,H,A,1.62,-0.78,1.713,,53.03,HHH,-1.423,0.100394,0.0132841,0.348868 kka2_1:8_F256P,kka2_1:8_256,Kka2,kka2_1:8,P00552,0.348868,NO,256,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.49,-4.358,2.868,,,H,A,1.62,-0.78,1.713,,53.03,HHH,-1.423,0.100394,0.0132841,0.348868 beta-lactamase_625_L218N,beta-lactamase_625_218,TEM-1,beta-lactamase_625,P62593,0.34892,NO,218,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.391,-3.851,2.46,,,I,b,0.55,-0.53,17.202,17.202,74.48,OHH,-1.58867,0.213352,0.00618274,0.34892 kka2_1:8_A215F,kka2_1:8_215,Kka2,kka2_1:8,P00552,0.349107,NO,215,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.968,-4.18,3.212,,0.039,E,B,1.04,-0.59,2.77,,50.38,HHA,-1.00467,0.100394,0.00529129,0.349107 kka2_1:8_A215F,kka2_1:8_215,Kka2,kka2_1:8,P00552,0.349107,NO,215,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.968,-4.18,3.212,,0.039,E,B,1.04,-0.59,2.77,,50.38,HHA,-1.00467,0.100394,0.00529129,0.349107 beta-lactamase_156_L74D,beta-lactamase_156_74,TEM-1,beta-lactamase_156,P62593,0.34911,NO,74,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.296,-4.023,2.727,,,H,A,0.55,-0.91,0.746,,50,HHO,-1.34933,0.111618,0.00493255,0.34911 kka2_1:1_T125F,kka2_1:1_125,Kka2,kka2_1:1,P00552,0.349227,NO,125,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.622,-4.443,1.821,,0.791,T,A,0.22,0.33,1.972,,92.05,BPH,-1.56933,0.520039,0.00821755,0.349227 kka2_1:1_I115M,kka2_1:1_115,Kka2,kka2_1:1,P00552,0.349245,NO,115,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.606,-2.756,1.15,,0.105,H,A,0.48,-1.18,0.878,,65.53,PHH,-2.205,0.520039,0.00836567,0.349245 beta-lactamase_2500_R220A,beta-lactamase_2500_220,TEM-1,beta-lactamase_2500,P62593,0.34932,NO,220,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-0.942,-2.357,1.415,,0.295,I,A,1.2,-0.76,2.175,,74.48,HBP,-1.33633,0.361275,0.00232421,0.34932 kka2_1:2_R258T,kka2_1:2_258,Kka2,kka2_1:2,P00552,0.349325,NO,258,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.626,-2.894,1.268,,0.316,H,A,1.2,-0.85,7.485,7.485,53.03,HBH,-1.25933,0.295029,0.00983174,0.349325 kka2_1:1_L165D,kka2_1:1_165,Kka2,kka2_1:1,P00552,0.349344,NO,165,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-2.453,-3.848,1.395,,0.299,,B,1.59,1.12,2.47,,64.39,OHH,-1.90967,0.520039,0.00801161,0.349344 kka2_1:1_P194A,kka2_1:1_194,Kka2,kka2_1:1,P00552,0.349374,NO,194,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.846,-3.118,2.272,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.520039,0.00314194,0.349374 beta-lactamase_I243S,beta-lactamase_243,TEM-1,beta-lactamase,P62593,0.349396,NO,243,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.532,-3.504,1.972,5.26886,,E,B,1.68,-1.24,2.289,,50,OHH,-1.46867,0.221079,0.00464034,0.349396 kka2_1:2_M197G,kka2_1:2_197,Kka2,kka2_1:2,P00552,0.349405,NO,197,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.707,-3.845,2.138,,0.121,E,B,0.55,-1.19,2.097,,65.53,HHH,-1.847,0.295029,0.00921295,0.349405 beta-lactamase_2500_L89D,beta-lactamase_2500_89,TEM-1,beta-lactamase_2500,P62593,0.349456,NO,89,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.096,-3.996,2.9,,0.168,T,A,0.55,0.63,2.066,,64.34,PHO,-1.75767,0.361275,0.00207068,0.349456 beta-lactamase_625_F70D,beta-lactamase_625_70,TEM-1,beta-lactamase_625,P62593,0.34946,NO,70,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.169,-3.91,2.741,,,H,A,0.58,-1.34,1.14,,63.99,PHB,-0.980667,0.213352,0.00193499,0.34946 beta-lactamase_F70K,beta-lactamase_70,TEM-1,beta-lactamase,P62593,0.349528,NO,70,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.169,-3.812,2.643,5.42055,,H,A,1.1,-1.34,1.14,,63.99,PHB,-0.980667,0.221079,0.00193499,0.349528 kka2_1:2_F240E,kka2_1:2_240,Kka2,kka2_1:2,P00552,0.349656,NO,240,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-0.911,-3.952,3.041,,,H,A,0.58,-1.21,0.373,,50.38,BHH,-1.67267,0.295029,0.00552543,0.349656 kka2_1:8_S32K,kka2_1:8_32,Kka2,kka2_1:8,P00552,0.349703,NO,32,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-0.804,-3.26,2.456,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.100394,0.00149998,0.349703 kka2_1:8_S32K,kka2_1:8_32,Kka2,kka2_1:8,P00552,0.349703,NO,32,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-0.804,-3.26,2.456,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.100394,0.00149998,0.349703 kka2_1:1_V113H,kka2_1:1_113,Kka2,kka2_1:1,P00552,0.349709,NO,113,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.233,-5.033,3.8,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.520039,0.00650191,0.349709 kka2_1:1_V113Y,kka2_1:1_113,Kka2,kka2_1:1,P00552,0.349709,NO,113,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.233,-4.11,2.877,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.520039,0.00650191,0.349709 kka2_1:1_A224T,kka2_1:1_224,Kka2,kka2_1:1,P00552,0.349896,NO,224,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.977,-1.898,0.921,,,H,A,0.46,-1.26,1.725,,63.64,HHP,-1.41033,0.520039,0.00352047,0.349896 kka2_1:1_R253A,kka2_1:1_253,Kka2,kka2_1:1,P00552,0.349904,NO,253,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.356,-2.382,1.026,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.520039,0.0144195,0.349904 kka2_1:4_D220L,kka2_1:4_220,Kka2,kka2_1:4,P00552,0.349909,NO,220,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.787,-3.669,2.882,,,H,A,0.75,-1.14,1.237,,46.59,PAH,-1.152,0.168804,0.00158066,0.349909 beta-lactamase_156_V72N,beta-lactamase_156_72,TEM-1,beta-lactamase_156,P62593,0.349918,NO,72,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.658,-4.143,2.485,,,H,A,0.44,-1.03,1.92,,65.73,BHH,-1.32167,0.111618,0.00501194,0.349918 beta-lactamase_D83L,beta-lactamase_83,TEM-1,beta-lactamase,P62593,0.349923,NO,83,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.066,-3.79,2.724,5.40616,0.354,H,A,1.33,0.22,0.861,,48.95,HAH,-1.34733,0.221079,0.00205968,0.349923 kka2_1:8_I141N,kka2_1:8_141,Kka2,kka2_1:8,P00552,0.349941,NO,141,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.495,-4.275,2.78,,0.068,H,A,1.52,-0.01,2.144,,92.05,BHA,-1.689,0.100394,0.00744745,0.349941 kka2_1:8_I141N,kka2_1:8_141,Kka2,kka2_1:8,P00552,0.349941,NO,141,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.495,-4.275,2.78,,0.068,H,A,1.52,-0.01,2.144,,92.05,BHA,-1.689,0.100394,0.00744745,0.349941 beta-lactamase_156_G76Q,beta-lactamase_156_76,TEM-1,beta-lactamase_156,P62593,0.349977,NO,76,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.189,-4.074,2.885,,,H,A,0.29,-0.67,3.059,,67.83,OOH,-1.22267,0.111618,0.00476637,0.349977 kka2_1:4_I207A,kka2_1:4_207,Kka2,kka2_1:4,P00552,0.35001,NO,207,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.175,-3.122,1.947,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.168804,0.00611824,0.35001 beta-lactamase_156_V260E,beta-lactamase_156_260,TEM-1,beta-lactamase_156,P62593,0.350015,NO,260,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.111618,0.00471757,0.350015 beta-lactamase_625_G43C,beta-lactamase_625_43,TEM-1,beta-lactamase_625,P62593,0.350028,NO,43,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.62,-5.087,4.467,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.213352,0.00120151,0.350028 kka2_1:1_D127A,kka2_1:1_127,Kka2,kka2_1:1,P00552,0.350082,NO,127,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.364,-2.492,1.128,,0.573,.,B,0.75,0.45,3.414,,50.38,HAO,-1.51067,0.520039,0.00660501,0.350082 kka2_1:1_L94Q,kka2_1:1_94,Kka2,kka2_1:1,P00552,0.350105,NO,94,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.618,-4.05,2.432,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.520039,0.00520888,0.350105 beta-lactamase_625_V72Y,beta-lactamase_625_72,TEM-1,beta-lactamase_625,P62593,0.350127,NO,72,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.658,-4.055,2.397,,,H,A,0.44,-1.03,0.981,,65.73,BHH,-1.32167,0.213352,0.00501194,0.350127 beta-lactamase_2500_R159P,beta-lactamase_2500_159,TEM-1,beta-lactamase_2500,P62593,0.350142,NO,159,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-0.94,-3.905,2.965,,0.316,,B,1.2,-0.55,2.341,,64.34,PBH,-1.011,0.361275,0.00108472,0.350142 beta-lactamase_2500_L28P,beta-lactamase_2500_28,TEM-1,beta-lactamase_2500,P62593,0.350275,NO,28,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.579,-4.027,2.448,,0.277,H,A,0.55,-0.16,2.716,,93.01,PHH,-2.11333,0.361275,0.00359321,0.350275 kka2_1:8_G245M,kka2_1:8_245,Kka2,kka2_1:8,P00552,0.350297,NO,245,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.812,-4.937,4.125,,0.655,T,g,0.75,0.03,1.148,,65.53,HOH,-1.19833,0.100394,0.00683899,0.350297 kka2_1:8_G245M,kka2_1:8_245,Kka2,kka2_1:8,P00552,0.350297,NO,245,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.812,-4.937,4.125,,0.655,T,g,0.75,0.03,1.148,,65.53,HOH,-1.19833,0.100394,0.00683899,0.350297 beta-lactamase_A124Q,beta-lactamase_124,TEM-1,beta-lactamase,P62593,0.350323,NO,124,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.181,-4.004,2.823,4.58507,,H,A,0.58,-0.9,2.273,,64.34,HHH,-1.152,0.221079,0.00481399,0.350323 beta-lactamase_V258F,beta-lactamase_258,TEM-1,beta-lactamase,P62593,0.350323,NO,258,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.975,-4.085,2.11,5.16083,,E,B,1.64,-1.02,2.124,,67.83,HHH,-1.67667,0.221079,0.007931,0.350323 kka2_1:1_G55P,kka2_1:1_55,Kka2,kka2_1:1,P00552,0.350371,NO,55,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.625,-4.068,2.443,,0.517,S,b,0.29,1.19,4.035,,63.64,POH,-2.05967,0.520039,0.00667877,0.350371 beta-lactamase_2500_P65H,beta-lactamase_2500_65,TEM-1,beta-lactamase_2500,P62593,0.350383,NO,65,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.894,-4.735,3.841,,0.098,E,B,0.52,-0.62,0.3,,40.56,HOH,-1.03233,0.361275,0.00152776,0.350383 kka2_1:1_K175T,kka2_1:1_175,Kka2,kka2_1:1,P00552,0.350406,NO,175,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-2.897,-2.9,0.003,,0.579,H,A,1.3,0.51,9.33,9.33,71.59,HBH,-1.82333,0.520039,0.00693093,0.350406 beta-lactamase_2500_D83K,beta-lactamase_2500_83,TEM-1,beta-lactamase_2500,P62593,0.350452,NO,83,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.066,-3.429,2.363,,0.354,H,A,0.75,0.22,0.239,,48.95,HAH,-1.34733,0.361275,0.00205968,0.350452 beta-lactamase_625_L191N,beta-lactamase_625_191,TEM-1,beta-lactamase_625,P62593,0.350497,NO,191,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.087,-4.164,3.077,,,H,A,0.55,0.09,1.908,,63.29,BHH,-1.445,0.213352,0.00263549,0.350497 kka2_1:1_S32F,kka2_1:1_32,Kka2,kka2_1:1,P00552,0.350506,NO,32,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-0.804,-4.095,3.291,,0.768,S,b,0.27,3.75,,,,OPA,-1.74533,0.520039,0.00149998,0.350506 kka2_1:1_D180K,kka2_1:1_180,Kka2,kka2_1:1,P00552,0.350519,NO,180,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.416,-2.839,0.423,,1.03,S,a,0.75,1.5,1.534,,71.59,OAO,-2.02933,0.520039,0.00756412,0.350519 kka2_1:8_L94K,kka2_1:8_94,Kka2,kka2_1:8,P00552,0.350535,NO,94,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.618,-3.731,2.113,,0.058,E,B,1.59,-0.52,2.197,,56.06,HHO,-1.612,0.100394,0.00520888,0.350535 kka2_1:8_L94K,kka2_1:8_94,Kka2,kka2_1:8,P00552,0.350535,NO,94,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.618,-3.731,2.113,,0.058,E,B,1.59,-0.52,2.197,,56.06,HHO,-1.612,0.100394,0.00520888,0.350535 kka2_1:1_C31T,kka2_1:1_31,Kka2,kka2_1:1,P00552,0.350567,NO,31,C,T,CT,Special,Polar,5.07,5.6,0.53,149,121,119,-2,108.5,116.1,7.6,-2.246,-3.606,1.36,,1.152,S,b,0.46,4.16,8.272,,63.26,OOP,-1.21533,0.520039,0.00681582,0.350567 kka2_1:1_A229G,kka2_1:1_229,Kka2,kka2_1:1,P00552,0.350597,NO,229,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.739,-2.492,0.753,,0.32,H,A,0.46,-0.7,6.549,,63.64,HHA,-1.851,0.520039,0.00942138,0.350597 kka2_1:2_L70Q,kka2_1:2_70,Kka2,kka2_1:2,P00552,0.350658,NO,70,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.017,-4.149,3.132,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.295029,0.00411884,0.350658 beta-lactamase_625_L73E,beta-lactamase_625_73,TEM-1,beta-lactamase_625,P62593,0.350683,NO,73,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.507,-3.924,2.417,,,H,A,0.55,-0.64,2.933,,67.83,HHH,-1.487,0.213352,0.00488983,0.350683 kka2_1:1_P179G,kka2_1:1_179,Kka2,kka2_1:1,P00552,0.350761,NO,179,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.974,-3.438,2.464,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.520039,0.00298346,0.350761 kka2_1:8_D101F,kka2_1:8_101,Kka2,kka2_1:8,P00552,0.350773,NO,101,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.028,-4.345,3.317,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.100394,0.00423361,0.350773 kka2_1:8_D101F,kka2_1:8_101,Kka2,kka2_1:8,P00552,0.350773,NO,101,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.028,-4.345,3.317,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.100394,0.00423361,0.350773 kka2_1:8_G201W,kka2_1:8_201,Kka2,kka2_1:8,P00552,0.350773,NO,201,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.56,-5.537,3.977,,0.149,T,l,0.75,-0.57,2.152,,52.65,POB,-1.92233,0.100394,0.00820117,0.350773 kka2_1:8_G201W,kka2_1:8_201,Kka2,kka2_1:8,P00552,0.350773,NO,201,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.56,-5.537,3.977,,0.149,T,l,0.75,-0.57,2.152,,52.65,POB,-1.92233,0.100394,0.00820117,0.350773 beta-lactamase_L136S,beta-lactamase_136,TEM-1,beta-lactamase,P62593,0.350788,NO,136,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.232,-3.705,2.473,5.31114,,H,A,2.89,-0.34,1.539,,48.95,HHH,-1.088,0.221079,0.00442304,0.350788 beta-lactamase_156_I229E,beta-lactamase_156_229,TEM-1,beta-lactamase_156,P62593,0.350828,NO,229,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.267,-3.864,2.597,,0.083,E,B,0.48,-0.76,1.114,,50,HHH,-1.58767,0.111618,0.00477249,0.350828 kka2_1:4_F203Q,kka2_1:4_203,Kka2,kka2_1:4,P00552,0.350892,NO,203,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-0.911,-4.376,3.465,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.168804,0.00318738,0.350892 beta-lactamase_39_M184P,beta-lactamase_39_184,TEM-1,beta-lactamase_39,P62593,0.350973,NO,184,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.593,-4.009,2.416,,,H,A,0.55,-0.87,2.893,,62.94,HHH,-1.41,0.0495842,0.00356019,0.350973 kka2_1:8_Y22G,kka2_1:8_22,Kka2,kka2_1:8,P00552,0.35101,NO,22,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-1.583,-2.411,0.828,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.100394,0.00598977,0.35101 kka2_1:8_Y22G,kka2_1:8_22,Kka2,kka2_1:8,P00552,0.35101,NO,22,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-1.583,-2.411,0.828,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.100394,0.00598977,0.35101 beta-lactamase_625_S104P,beta-lactamase_625_104,TEM-1,beta-lactamase_625,P62593,0.351029,NO,104,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.015,-3.751,2.736,,0.04,,b,0.27,0.57,1.76,,63.29,HPO,-1.05267,0.213352,0.00218083,0.351029 kka2_1:4_S204F,kka2_1:4_204,Kka2,kka2_1:4,P00552,0.351031,NO,204,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.353,-4.232,2.879,,0.144,E,A,0.27,-1.2,2.442,,65.53,HPO,-0.953333,0.168804,0.00881794,0.351031 beta-lactamase_625_L188N,beta-lactamase_625_188,TEM-1,beta-lactamase_625,P62593,0.351038,NO,188,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.166,-4.122,2.956,,,H,A,0.55,-0.3,2.982,,60.14,PHB,-1.47033,0.213352,0.00295687,0.351038 beta-lactamase_0_S128L,beta-lactamase_0_128,TEM-1,beta-lactamase_0,P62593,0.351078,NO,128,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-0.84,-3.358,2.518,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.0500837,0.00071483,0.351078 beta-lactamase_2500_L219H,beta-lactamase_2500_219,TEM-1,beta-lactamase_2500,P62593,0.351101,NO,219,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.313,-4.957,3.644,,,I,A,0.55,-0.51,35.994,35.994,74.48,HHB,-1.21533,0.361275,0.00664345,0.351101 kka2_1:2_A222R,kka2_1:2_222,Kka2,kka2_1:2,P00552,0.351101,NO,222,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.725,-3.736,3.011,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.295029,0.00207657,0.351101 kka2_1:2_D190C,kka2_1:2_190,Kka2,kka2_1:2,P00552,0.351109,NO,190,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.708,-5.115,4.407,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.295029,0.00247989,0.351109 kka2_1:1_Q27D,kka2_1:1_27,Kka2,kka2_1:1,P00552,0.351131,NO,27,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-1.659,-1.745,0.086,,0.608,.,A,0.64,0.71,0.521,,65.53,PPP,-1.90733,0.520039,0.00595365,0.351131 kka2_1:1_Q136N,kka2_1:1_136,Kka2,kka2_1:1,P00552,0.351156,NO,136,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-3.021,-3.645,0.624,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.520039,0.00624149,0.351156 beta-lactamase_39_A247P,beta-lactamase_39_247,TEM-1,beta-lactamase_39,P62593,0.35119,NO,247,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.0495842,0.00611275,0.35119 kka2_1:1_A14M,kka2_1:1_14,Kka2,kka2_1:1,P00552,0.351194,NO,14,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.837,-4.736,2.899,,0.728,G,A,0.46,0.7,1.17,,71.59,HHH,-1.82567,0.520039,0.00706614,0.351194 kka2_1:2_I221E,kka2_1:2_221,Kka2,kka2_1:2,P00552,0.351278,NO,221,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.739,-4.003,2.264,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.295029,0.00945908,0.351278 kka2_1:4_A237G,kka2_1:4_237,Kka2,kka2_1:4,P00552,0.351332,NO,237,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.12,-3.628,1.508,,0.068,H,A,0.46,-0.71,2.444,,92.05,HHA,-2.10433,0.168804,0.012257,0.351332 kka2_1:1_D250C,kka2_1:1_250,Kka2,kka2_1:1,P00552,0.351375,NO,250,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.015,-5.204,4.189,,0.274,.,b,0.75,-0.46,4.177,,51.89,OAP,-1.83933,0.520039,0.0177103,0.351375 kka2_1:4_R253I,kka2_1:4_253,Kka2,kka2_1:4,P00552,0.351378,NO,253,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.356,-4.056,2.7,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.168804,0.0144195,0.351378 beta-lactamase_39_C121D,beta-lactamase_39_121,TEM-1,beta-lactamase_39,P62593,0.35139,NO,121,C,D,CD,Special,negativeCharge,5.07,5.0516,-0.0184,154,121,133,12,108.5,111.1,2.6,-0.953,-3.916,2.963,,,H,A,0.46,-0.81,7.644,,63.29,HOP,-1.46767,0.0495842,0.000744322,0.35139 kka2_1:1_D250H,kka2_1:1_250,Kka2,kka2_1:1,P00552,0.351444,NO,250,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.015,-4.493,3.478,,0.274,.,b,0.75,-0.46,4.177,,51.89,OAP,-1.83933,0.520039,0.0177103,0.351444 kka2_1:1_R202N,kka2_1:1_202,Kka2,kka2_1:1,P00552,0.351459,NO,202,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.761,-3.087,1.326,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.520039,0.00696498,0.351459 kka2_1:1_E262T,kka2_1:1_262,Kka2,kka2_1:1,P00552,0.351463,NO,262,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-0.829,-3.473,2.644,,0.059,G,A,1.04,-0.18,0.837,,42.42,AAH,-0.816,0.520039,0.0191586,0.351463 kka2_1:4_G233T,kka2_1:4_233,Kka2,kka2_1:4,P00552,0.351524,NO,233,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.748,-3.674,2.926,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.168804,0.00232366,0.351524 beta-lactamase_G236I,beta-lactamase_236,TEM-1,beta-lactamase,P62593,0.351529,NO,236,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.784,-4.139,3.355,4.7915,0.241,,b,0.23,-0.59,1.883,,64.69,HOA,-1.36933,0.221079,0.00162372,0.351529 beta-lactamase_625_P181M,beta-lactamase_625_181,TEM-1,beta-lactamase_625,P62593,0.351567,NO,181,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.813,-4.702,3.889,,,H,A,0.52,-1.14,1.797,,61.54,HOH,-1.795,0.213352,0.000703122,0.351567 kka2_1:4_G210I,kka2_1:4_210,Kka2,kka2_1:4,P00552,0.351572,NO,210,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.095,-4.061,2.966,,0.103,T,A,0.29,-0.62,0.271,,50,OOB,-0.966667,0.168804,0.00598378,0.351572 kka2_1:4_C192E,kka2_1:4_192,Kka2,kka2_1:4,P00552,0.351665,NO,192,C,E,CE,Special,negativeCharge,5.07,3.22,-1.85,170,121,147,26,108.5,138.4,29.9,-1.067,-3.955,2.888,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.168804,0.00485428,0.351665 beta-lactamase_2500_R91F,beta-lactamase_2500_91,TEM-1,beta-lactamase_2500,P62593,0.351747,NO,91,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.392,-4.376,2.984,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.361275,0.00380226,0.351747 kka2_1:8_A119P,kka2_1:8_119,Kka2,kka2_1:8,P00552,0.351839,NO,119,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.073,-3.813,2.74,,0.019,H,A,0.46,-0.57,1.511,,71.59,AHH,-2.34,0.100394,0.00441074,0.351839 kka2_1:8_A119P,kka2_1:8_119,Kka2,kka2_1:8,P00552,0.351839,NO,119,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.073,-3.813,2.74,,0.019,H,A,0.46,-0.57,1.511,,71.59,AHH,-2.34,0.100394,0.00441074,0.351839 beta-lactamase_2500_A235P,beta-lactamase_2500_235,TEM-1,beta-lactamase_2500,P62593,0.351874,NO,235,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.266,-3.821,2.555,,0.32,E,B,0.46,-0.86,0.891,,50,OHO,-0.89,0.361275,0.00493474,0.351874 kka2_1:1_S104C,kka2_1:1_104,Kka2,kka2_1:1,P00552,0.351891,NO,104,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.436,-3.387,1.951,,0.536,T,A,0.27,-1.11,5.49,,63.64,HPP,-1.91433,0.520039,0.00555207,0.351891 E1_Ubiquitin_I44E,E1_Ubiquitin_44,Uba1,E1_Ubiquitin,P0CG63,0.351901,NO,44,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.432,-3.589,2.157,,,E,B,0.27,-1.17,4.57,,78.74,HHH,-1.25633,0.18783,0.00209731,0.351901 kka2_1:2_S105K,kka2_1:2_105,Kka2,kka2_1:2,P00552,0.351932,NO,105,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.945,-3.628,1.683,,0.056,S,B,0.27,-1.04,3.442,,65.53,PPB,-2.17033,0.295029,0.00847233,0.351932 beta-lactamase_625_Y262S,beta-lactamase_625_262,TEM-1,beta-lactamase_625,P62593,0.351952,NO,262,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.213352,0.00853516,0.351952 kka2_1:8_F264P,kka2_1:8_264,Kka2,kka2_1:8,P00552,0.352076,NO,264,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.02,-4.363,3.343,,0.296,,?,1.62,0.02,1.553,,71.59,HHO,-0.9655,0.100394,,0.352076 kka2_1:8_F264P,kka2_1:8_264,Kka2,kka2_1:8,P00552,0.352076,NO,264,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.02,-4.363,3.343,,0.296,,?,1.62,0.02,1.553,,71.59,HHO,-0.9655,0.100394,,0.352076 kka2_1:4_K112E,kka2_1:4_112,Kka2,kka2_1:4,P00552,0.352284,NO,112,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-2.491,-3.666,1.175,,0.076,H,A,2.34,-1.37,0.39,,56.06,ABH,-2.00133,0.168804,0.00645389,0.352284 kka2_1:1_Q26M,kka2_1:1_26,Kka2,kka2_1:1,P00552,0.352297,NO,26,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.18,-3.49,1.31,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.520039,0.00708962,0.352297 kka2_1:1_E111L,kka2_1:1_111,Kka2,kka2_1:1,P00552,0.352328,NO,111,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.28,-3.101,0.821,,0.155,H,A,1.52,-1.14,15.716,15.716,65.53,HAB,-2.27833,0.520039,0.00746789,0.352328 beta-lactamase_156_V72Q,beta-lactamase_156_72,TEM-1,beta-lactamase_156,P62593,0.352366,NO,72,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.658,-4.185,2.527,,,H,A,0.44,-1.03,1.92,,65.73,BHH,-1.32167,0.111618,0.00501194,0.352366 beta-lactamase_625_L218D,beta-lactamase_625_218,TEM-1,beta-lactamase_625,P62593,0.352368,NO,218,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.391,-3.905,2.514,,,I,b,0.55,-0.53,17.202,17.202,74.48,OHH,-1.58867,0.213352,0.00618274,0.352368 beta-lactamase_625_R242P,beta-lactamase_625_242,TEM-1,beta-lactamase_625,P62593,0.352468,NO,242,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.213352,0.00452879,0.352468 beta-lactamase_I275A,beta-lactamase_275,TEM-1,beta-lactamase,P62593,0.352494,NO,275,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.397,-3.2,1.803,5.3999,0.015,H,A,1,-0.52,0.836,,62.59,PHH,-1.541,0.221079,0.0141984,0.352494 kka2_1:4_W15N,kka2_1:4_15,Kka2,kka2_1:4,P00552,0.352542,NO,15,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-1.392,-4.342,2.95,,0.01,G,A,0.47,0.15,0.943,,52.27,HHH,-2.10533,0.168804,0.00585505,0.352542 kka2_1:8_R211A,kka2_1:8_211,Kka2,kka2_1:8,P00552,0.352548,NO,211,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-0.899,-3.167,2.268,,0.12,T,a,0.16,-0.39,0.615,,49.62,OBH,-0.966,0.100394,0.00204888,0.352548 kka2_1:8_R211A,kka2_1:8_211,Kka2,kka2_1:8,P00552,0.352548,NO,211,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-0.899,-3.167,2.268,,0.12,T,a,0.16,-0.39,0.615,,49.62,OBH,-0.966,0.100394,0.00204888,0.352548 kka2_1:1_I228E,kka2_1:1_228,Kka2,kka2_1:1,P00552,0.352651,NO,228,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.142,-3.95,2.808,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.520039,0.00458834,0.352651 kka2_1:8_A117K,kka2_1:8_117,Kka2,kka2_1:8,P00552,0.352666,NO,117,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.828,-3.549,2.721,,,H,A,1.04,-0.78,0.755,,45.83,HHA,-1.79333,0.100394,0.00282984,0.352666 kka2_1:8_A117K,kka2_1:8_117,Kka2,kka2_1:8,P00552,0.352666,NO,117,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.828,-3.549,2.721,,,H,A,1.04,-0.78,0.755,,45.83,HHA,-1.79333,0.100394,0.00282984,0.352666 kka2_1:8_N195G,kka2_1:8_195,Kka2,kka2_1:8,P00552,0.352666,NO,195,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-0.836,-2.98,2.144,,0.037,G,A,0.43,-1.36,1.108,,48.11,OPH,-1.26567,0.100394,0.00276134,0.352666 kka2_1:8_N195G,kka2_1:8_195,Kka2,kka2_1:8,P00552,0.352666,NO,195,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-0.836,-2.98,2.144,,0.037,G,A,0.43,-1.36,1.108,,48.11,OPH,-1.26567,0.100394,0.00276134,0.352666 kka2_1:2_L259S,kka2_1:2_259,Kka2,kka2_1:2,P00552,0.352668,NO,259,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.088,-3.523,2.435,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.295029,0.0206964,0.352668 beta-lactamase_156_A246W,beta-lactamase_156_246,TEM-1,beta-lactamase_156,P62593,0.352771,NO,246,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.121,-5.267,3.146,,0.01,E,B,0.46,-1.01,1.959,,73.78,HHH,-1.55633,0.111618,0.00569458,0.352771 kka2_1:1_L184D,kka2_1:1_184,Kka2,kka2_1:1,P00552,0.352784,NO,184,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.496,-4.1,2.604,,0.489,E,B,0.55,-0.06,19.127,19.127,63.26,AHH,-1.24833,0.520039,0.00518742,0.352784 beta-lactamase_625_L73R,beta-lactamase_625_73,TEM-1,beta-lactamase_625,P62593,0.35281,NO,73,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.507,-4.144,2.637,,,H,A,0.55,-0.64,2.933,,67.83,HHH,-1.487,0.213352,0.00488983,0.35281 beta-lactamase_V157P,beta-lactamase_157,TEM-1,beta-lactamase,P62593,0.352829,NO,157,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.751,-4.03,2.279,5.51733,0.308,S,a,0.96,-0.75,1.847,,69.58,BHP,-2.00767,0.221079,0.00506849,0.352829 Pab1_I157P,Pab1_157,Pab1,Pab1,P04147,0.352861,NO,157,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.623,-3.862,2.239,,,,,,,1.439,,79.72,BHH,-1.28667,0.175299,0.0018103,0.352861 beta-lactamase_625_L150D,beta-lactamase_625_150,TEM-1,beta-lactamase_625,P62593,0.352867,NO,150,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.326,-4.043,2.717,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.213352,0.00463171,0.352867 kka2_1:1_L241Y,kka2_1:1_241,Kka2,kka2_1:1,P00552,0.352894,NO,241,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.158,-3.64,2.482,,0.08,H,A,0.55,-0.82,1.685,,63.26,HHH,-1.58533,0.520039,0.0117299,0.352894 kka2_1:1_G233D,kka2_1:1_233,Kka2,kka2_1:1,P00552,0.352925,NO,233,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.748,-2.136,1.388,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.520039,0.00232366,0.352925 kka2_1:8_D216M,kka2_1:8_216,Kka2,kka2_1:8,P00552,0.352931,NO,216,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.785,-4.956,4.171,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.100394,0.00229969,0.352931 kka2_1:8_D216M,kka2_1:8_216,Kka2,kka2_1:8,P00552,0.352931,NO,216,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.785,-4.956,4.171,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.100394,0.00229969,0.352931 kka2_1:1_F256E,kka2_1:1_256,Kka2,kka2_1:1,P00552,0.352988,NO,256,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.49,-3.921,2.431,,,H,A,1.62,-0.78,2.354,,53.03,HHH,-1.423,0.520039,0.0132841,0.352988 kka2_1:1_D159W,kka2_1:1_159,Kka2,kka2_1:1,P00552,0.353,NO,159,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.82,-5.531,4.711,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.520039,0.0030485,0.353 kka2_1:1_L53C,kka2_1:1_53,Kka2,kka2_1:1,P00552,0.353006,NO,53,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-2.681,-5.19,2.509,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.520039,0.00671168,0.353006 beta-lactamase_156_T107H,beta-lactamase_156_107,TEM-1,beta-lactamase_156,P62593,0.353053,NO,107,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.117,-4.67,3.553,,,G,A,0.22,-0.06,0.341,,67.83,HPA,-1.265,0.111618,0.00239347,0.353053 kka2_1:1_R202D,kka2_1:1_202,Kka2,kka2_1:1,P00552,0.353113,NO,202,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.761,-2.83,1.069,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.520039,0.00696498,0.353113 kka2_1:8_K50D,kka2_1:8_50,Kka2,kka2_1:8,P00552,0.353138,NO,50,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-0.833,-3.541,2.708,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.100394,0.00138626,0.353138 kka2_1:8_K50D,kka2_1:8_50,Kka2,kka2_1:8,P00552,0.353138,NO,50,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-0.833,-3.541,2.708,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.100394,0.00138626,0.353138 kka2_1:1_G245K,kka2_1:1_245,Kka2,kka2_1:1,P00552,0.353184,NO,245,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.812,-3.635,2.823,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.520039,0.00683899,0.353184 beta-lactamase_2500_S266L,beta-lactamase_2500_266,TEM-1,beta-lactamase_2500,P62593,0.353201,NO,266,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.361275,0.0140785,0.353201 beta-lactamase_2500_V117N,beta-lactamase_2500_117,TEM-1,beta-lactamase_2500,P62593,0.353202,NO,117,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.53,-4.224,2.694,,,H,A,0.44,-0.34,1.23,,65.03,PHB,-1.741,0.361275,0.00467906,0.353202 beta-lactamase_L74Q,beta-lactamase_74,TEM-1,beta-lactamase,P62593,0.353251,NO,74,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.296,-4.107,2.811,5.50288,,H,A,1.75,-0.91,1.581,,50,HHO,-1.34933,0.221079,0.00493255,0.353251 kka2_1:2_V97D,kka2_1:2_97,Kka2,kka2_1:2,P00552,0.353272,NO,97,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.453,-4.157,2.704,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.295029,0.00737869,0.353272 kka2_1:2_S32K,kka2_1:2_32,Kka2,kka2_1:2,P00552,0.353299,NO,32,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-0.804,-3.26,2.456,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.295029,0.00149998,0.353299 beta-lactamase_S57P,beta-lactamase_57,TEM-1,beta-lactamase,P62593,0.353301,NO,57,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.918,-3.952,2.034,5.64201,0.352,E,B,0.25,-0.18,1.971,,72.73,APH,-2.29167,0.221079,0.00492804,0.353301 kka2_1:1_F37W,kka2_1:1_37,Kka2,kka2_1:1,P00552,0.353317,NO,37,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.427,-2.717,1.29,,0.219,E,B,0.58,-0.25,18.64,18.64,64.39,HHB,-1.17733,0.520039,0.00586193,0.353317 kka2_1:2_D183Y,kka2_1:2_183,Kka2,kka2_1:2,P00552,0.353365,NO,183,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.204,-4.387,3.183,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.295029,0.00426304,0.353365 beta-lactamase_2500_M67E,beta-lactamase_2500_67,TEM-1,beta-lactamase_2500,P62593,0.353475,NO,67,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-2.231,-3.761,1.53,,0.006,G,P,0.55,-0.81,2.653,,65.03,HHP,-1.502,0.361275,0.00409753,0.353475 kka2_1:1_Y257T,kka2_1:1_257,Kka2,kka2_1:1,P00552,0.353475,NO,257,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-1.064,-3.734,2.67,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.520039,0.0148191,0.353475 kka2_1:8_I228W,kka2_1:8_228,Kka2,kka2_1:8,P00552,0.353491,NO,228,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.142,-5.373,4.231,,,H,A,1.52,-1.2,1.521,,71.59,AHH,-1.54633,0.100394,0.00458834,0.353491 kka2_1:8_I228W,kka2_1:8_228,Kka2,kka2_1:8,P00552,0.353491,NO,228,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.142,-5.373,4.231,,,H,A,1.52,-1.2,1.521,,71.59,AHH,-1.54633,0.100394,0.00458834,0.353491 gb1_A260Y,gb1_260,gb1,gb1,P06654,0.353558,NO,260,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.486,-3.909,2.423,,,,,,,0.173,,9.6,HHP,-1.70967,0.177985,0.0055808,0.353558 gb1_F278A,gb1_278,gb1,gb1,P06654,0.353558,NO,278,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.418,-3.073,1.655,,,,,,,3.233,,35.71,PHP,-1.503,0.177985,0.00295699,0.353558 gb1_N261F,gb1_261,gb1,gb1,P06654,0.353558,NO,261,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-1.863,-4.025,2.162,,,,,,,1.191,,44.87,HPA,-2.16033,0.177985,0.0061875,0.353558 beta-lactamase_625_A132E,beta-lactamase_625_132,TEM-1,beta-lactamase_625,P62593,0.353567,NO,132,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.9,-3.484,2.584,,,H,A,0.46,-0.93,0.316,,64.69,PHH,-1.138,0.213352,0.000962524,0.353567 beta-lactamase_E35L,beta-lactamase_35,TEM-1,beta-lactamase,P62593,0.35358,NO,35,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-0.869,-3.632,2.763,5.10723,0.15,H,A,0.52,0.21,1.081,,46.85,HAA,-1.88667,0.221079,0.00174441,0.35358 beta-lactamase_N272L,beta-lactamase_272,TEM-1,beta-lactamase,P62593,0.35358,NO,272,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-1.127,-3.672,2.545,5.37826,0.081,H,A,0.09,-0.97,1.468,,63.64,BPB,-1.56333,0.221079,0.00545371,0.35358 beta-lactamase_2500_S201P,beta-lactamase_2500_201,TEM-1,beta-lactamase_2500,P62593,0.353589,NO,201,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.183,-3.79,2.607,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.361275,0.00198815,0.353589 kka2_1:1_P179F,kka2_1:1_179,Kka2,kka2_1:1,P00552,0.353605,NO,179,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.974,-4.355,3.381,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.520039,0.00298346,0.353605 beta-lactamase_2500_E56I,beta-lactamase_2500_56,TEM-1,beta-lactamase_2500,P62593,0.353612,NO,56,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.043,-3.825,1.782,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.361275,0.00238534,0.353612 hsp90_G584R,hsp90_584,hsp90,hsp90,P02829,0.3537,NO,584,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-2.511,-3.086,0,5.20094,0.414,S,b,0.84,0.33,,,,HOH,-3.32733,0.368192,0.000222939,0.3537 kka2_1:4_G201Y,kka2_1:4_201,Kka2,kka2_1:4,P00552,0.353704,NO,201,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.56,-4.462,2.902,,0.149,T,l,0.29,-0.57,0.284,,52.65,POB,-1.92233,0.168804,0.00820117,0.353704 kka2_1:1_L102S,kka2_1:1_102,Kka2,kka2_1:1,P00552,0.353722,NO,102,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.804,-3.637,2.833,,,T,A,0.55,-1.17,4.258,,42.42,AHH,-1.398,0.520039,0.00201332,0.353722 kka2_1:2_D82R,kka2_1:2_82,Kka2,kka2_1:2,P00552,0.353782,NO,82,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.946,-2.957,1.011,,0.341,E,b,0.75,0.52,11.923,11.923,63.64,HAH,-1.98,0.295029,0.00637516,0.353782 kka2_1:1_D157H,kka2_1:1_157,Kka2,kka2_1:1,P00552,0.353794,NO,157,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.993,-4.51,3.517,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.520039,0.0042313,0.353794 beta-lactamase_2500_A40D,beta-lactamase_2500_40,TEM-1,beta-lactamase_2500,P62593,0.353808,NO,40,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.402,-3.685,2.283,,0.155,S,B,0.46,0.21,0.953,,73.78,OHB,-1.40267,0.361275,0.00490026,0.353808 kka2_1:4_H135L,kka2_1:4_135,Kka2,kka2_1:4,P00552,0.353831,NO,135,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-1.331,-2.788,1.457,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.168804,0.00532566,0.353831 beta-lactamase_625_L218S,beta-lactamase_625_218,TEM-1,beta-lactamase_625,P62593,0.353881,NO,218,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.391,-2.79,1.399,,,I,b,0.55,-0.53,17.202,17.202,74.48,OHH,-1.58867,0.213352,0.00618274,0.353881 kka2_1:1_P179V,kka2_1:1_179,Kka2,kka2_1:1,P00552,0.353903,NO,179,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.974,-3.463,2.489,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.520039,0.00298346,0.353903 kka2_1:2_M120A,kka2_1:2_120,Kka2,kka2_1:2,P00552,0.353919,NO,120,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-3.877,-3.104,-0.773,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.295029,0.00265808,0.353919 kka2_1:1_A129Q,kka2_1:1_129,Kka2,kka2_1:1,P00552,0.353924,NO,129,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.656,-3.989,2.333,,0.845,G,A,0.46,0.72,19.686,19.686,92.05,OHP,-1.99,0.520039,0.00726862,0.353924 kka2_1:1_A229V,kka2_1:1_229,Kka2,kka2_1:1,P00552,0.353934,NO,229,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.739,-2.471,0.732,,0.32,H,A,0.46,-0.7,6.549,,63.64,HHA,-1.851,0.520039,0.00942138,0.353934 beta-lactamase_625_S104D,beta-lactamase_625_104,TEM-1,beta-lactamase_625,P62593,0.354003,NO,104,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.015,-3.41,2.395,,0.04,,b,0.27,0.57,1.76,,63.29,HPO,-1.05267,0.213352,0.00218083,0.354003 kka2_1:4_L259R,kka2_1:4_259,Kka2,kka2_1:4,P00552,0.354012,NO,259,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.088,-3.982,2.894,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.168804,0.0206964,0.354012 kka2_1:1_Y22E,kka2_1:1_22,Kka2,kka2_1:1,P00552,0.35406,NO,22,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-1.583,-3.743,2.16,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.520039,0.00598977,0.35406 beta-lactamase_W208V,beta-lactamase_208,TEM-1,beta-lactamase,P62593,0.354104,NO,208,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-0.818,-3.754,2.936,5.26277,0.067,H,A,0.99,-0.65,,,,AHH,-1.44133,0.221079,0.00126609,0.354104 beta-lactamase_2500_L223P,beta-lactamase_2500_223,TEM-1,beta-lactamase_2500,P62593,0.354113,NO,223,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.055,-4.101,3.046,,0.27,,B,0.55,0.09,1.334,,74.48,HHO,-1.35033,0.361275,0.00372793,0.354113 kka2_1:2_K112M,kka2_1:2_112,Kka2,kka2_1:2,P00552,0.354126,NO,112,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-2.491,-4.49,1.999,,0.076,H,A,2.34,-1.37,23.433,23.433,56.06,ABH,-2.00133,0.295029,0.00645389,0.354126 kka2_1:4_A215N,kka2_1:4_215,Kka2,kka2_1:4,P00552,0.354219,NO,215,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.968,-3.769,2.801,,0.039,E,B,0.46,-0.59,0.754,,50.38,HHA,-1.00467,0.168804,0.00529129,0.354219 beta-lactamase_A133P,beta-lactamase_133,TEM-1,beta-lactamase,P62593,0.354295,NO,133,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.186,-3.811,2.625,4.86423,,H,A,0.55,-0.86,2.649,,67.83,HHP,-0.988333,0.221079,0.00468022,0.354295 Pab1_I130G,Pab1_130,Pab1,Pab1,P04147,0.354302,NO,130,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.212,-3.625,2.413,,,E,B,1.23,0.01,,,,HHB,-1.188,0.175299,0.000351112,0.354302 kka2_1:1_S105C,kka2_1:1_105,Kka2,kka2_1:1,P00552,0.354323,NO,105,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.945,-3.198,1.253,,0.056,S,B,0.27,-1.04,3.442,,65.53,PPB,-2.17033,0.520039,0.00847233,0.354323 kka2_1:4_L223A,kka2_1:4_223,Kka2,kka2_1:4,P00552,0.354358,NO,223,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.861,-3.151,2.29,,,H,A,1.59,-1.24,1.268,,50,HHH,-0.854333,0.168804,0.00253574,0.354358 kka2_1:4_L223C,kka2_1:4_223,Kka2,kka2_1:4,P00552,0.354358,NO,223,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.861,-4.71,3.849,,,H,A,1.59,-1.24,1.268,,50,HHH,-0.854333,0.168804,0.00253574,0.354358 kka2_1:4_R239D,kka2_1:4_239,Kka2,kka2_1:4,P00552,0.354378,NO,239,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.949,-2.803,-0.146,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.168804,0.00835326,0.354378 kka2_1:2_W236H,kka2_1:2_236,Kka2,kka2_1:2,P00552,0.354464,NO,236,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-1.363,-4.78,3.417,,0.303,H,A,1.51,-0.76,5.58,,48.48,AHH,-1.81267,0.295029,0.0088796,0.354464 kka2_1:1_G210M,kka2_1:1_210,Kka2,kka2_1:1,P00552,0.354534,NO,210,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.095,-4.836,3.741,,0.103,T,A,0.29,-0.62,14.483,14.483,50,OOB,-0.966667,0.520039,0.00598378,0.354534 kka2_1:2_D220F,kka2_1:2_220,Kka2,kka2_1:2,P00552,0.354534,NO,220,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.787,-4.288,3.501,,,H,A,0.75,-1.14,0.745,,46.59,PAH,-1.152,0.295029,0.00158066,0.354534 beta-lactamase_2500_G236D,beta-lactamase_2500_236,TEM-1,beta-lactamase_2500,P62593,0.354557,NO,236,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.784,-3.513,2.729,,0.241,,b,0.29,-0.59,2.14,,64.69,HOO,-1.025,0.361275,0.00162372,0.354557 kka2_1:8_R217D,kka2_1:8_217,Kka2,kka2_1:8,P00552,0.354564,NO,217,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.158,-3.819,2.661,,0.252,T,A,0.16,-0.59,1.151,,52.27,ABH,-1.127,0.100394,0.0047191,0.354564 kka2_1:8_R217D,kka2_1:8_217,Kka2,kka2_1:8,P00552,0.354564,NO,217,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.158,-3.819,2.661,,0.252,T,A,0.16,-0.59,1.151,,52.27,ABH,-1.127,0.100394,0.0047191,0.354564 kka2_1:1_R202Q,kka2_1:1_202,Kka2,kka2_1:1,P00552,0.35461,NO,202,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.761,-2.622,0.861,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.520039,0.00696498,0.35461 beta-lactamase_2500_V78F,beta-lactamase_2500_78,TEM-1,beta-lactamase_2500,P62593,0.354651,NO,78,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.459,-3.883,2.424,,,H,A,0.44,-0.47,31.376,31.376,63.64,HHH,-1.17833,0.361275,0.00492501,0.354651 beta-lactamase_625_E119L,beta-lactamase_625_119,TEM-1,beta-lactamase_625,P62593,0.354658,NO,119,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.412,-3.669,2.257,,0.358,H,A,1.04,0.51,1.034,,63.99,BAH,-1.623,0.213352,0.00386966,0.354658 kka2_1:2_A191N,kka2_1:2_191,Kka2,kka2_1:2,P00552,0.354671,NO,191,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.831,-3.96,3.129,,,.,b,0.46,-0.94,2.046,,50,AHO,-0.868667,0.295029,0.00338807,0.354671 kka2_1:2_I207L,kka2_1:2_207,Kka2,kka2_1:2,P00552,0.354829,NO,207,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.175,-2.098,0.923,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.295029,0.00611824,0.354829 Ubiquitin_I44W,Ubiquitin_44,Uba1,Ubiquitin,P0CG48,0.354839,NO,44,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.566,-5.273,3.707,4.71256,,E,B,0.27,-1.17,5.26,,39.71,HHH,-1.38567,0.205827,0.000613305,0.354839 Ubiquitin_K48N,Ubiquitin_48,Uba1,Ubiquitin,P0CG48,0.354839,NO,48,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.436,-3.532,2.096,5.03072,0.132,E,B,2.92,-0.28,1.539,,53.87,OBP,-1.6,0.205827,0.000394633,0.354839 kka2_1:1_W91I,kka2_1:1_91,Kka2,kka2_1:1,P00552,0.354923,NO,91,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-1.178,-3.942,2.764,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.520039,0.00358653,0.354923 beta-lactamase_2500_L79A,beta-lactamase_2500_79,TEM-1,beta-lactamase_2500,P62593,0.354944,NO,79,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.842,-3.103,2.261,,0.007,H,A,0.55,-0.16,0.823,,50.35,HHP,-1.44333,0.361275,0.000947397,0.354944 beta-lactamase_M184H,beta-lactamase_184,TEM-1,beta-lactamase,P62593,0.354977,NO,184,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.593,-4.818,3.225,5.39575,,H,A,1.3,-0.87,2.893,,62.94,HHH,-1.41,0.221079,0.00356019,0.354977 kka2_1:4_Y244Q,kka2_1:4_244,Kka2,kka2_1:4,P00552,0.354985,NO,244,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-0.775,-3.928,3.153,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.168804,0.00453187,0.354985 beta-lactamase_2500_L146Y,beta-lactamase_2500_146,TEM-1,beta-lactamase_2500,P62593,0.355006,NO,146,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.462,-3.821,2.359,,0.007,H,A,0.55,-0.56,1.578,,64.69,AHP,-1.656,0.361275,0.00474542,0.355006 kka2_1:1_S204F,kka2_1:1_204,Kka2,kka2_1:1,P00552,0.355027,NO,204,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.353,-4.232,2.879,,0.144,E,A,0.27,-1.2,3.022,,65.53,HPO,-0.953333,0.520039,0.00881794,0.355027 Pab1_H172T,Pab1_172,Pab1,Pab1,P04147,0.355049,NO,172,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-1.21,-3.464,2.254,,0.076,E,B,0.35,-0.87,,,,HBH,-1.26667,0.175299,0.000296642,0.355049 WW_domain_L190P,WW_domain_190,Yap65,WW_domain,P46937,0.355054,NO,190,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.404,-4.039,2.635,5.53598,,,,,,0.645,,56.55,HHP,-1.51833,0.153962,0.00249186,0.355054 kka2_1:2_I254H,kka2_1:2_254,Kka2,kka2_1:2,P00552,0.355064,NO,254,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.933,-4.91,2.977,,0.135,H,A,1.52,-0.6,2.562,,71.59,BHH,-1.668,0.295029,0.0132375,0.355064 beta-lactamase_625_D174F,beta-lactamase_625_174,TEM-1,beta-lactamase_625,P62593,0.355073,NO,174,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.738,-4.292,3.554,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.213352,0.00125633,0.355073 kka2_1:1_D23M,kka2_1:1_23,Kka2,kka2_1:1,P00552,0.355102,NO,23,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.459,-4.807,2.348,,0.695,E,B,0.75,-0.65,2.655,,65.53,HAH,-1.94033,0.520039,0.007195,0.355102 kka2_1:1_T85L,kka2_1:1_85,Kka2,kka2_1:1,P00552,0.355115,NO,85,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.165,-2.782,0.617,,0.576,E,B,0.82,1.39,16.653,16.653,71.59,HPA,-2.10133,0.520039,0.00634493,0.355115 kka2_1:8_I228K,kka2_1:8_228,Kka2,kka2_1:8,P00552,0.355135,NO,228,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.142,-3.919,2.777,,,H,A,1.52,-1.2,1.521,,71.59,AHH,-1.54633,0.100394,0.00458834,0.355135 kka2_1:8_I228K,kka2_1:8_228,Kka2,kka2_1:8,P00552,0.355135,NO,228,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.142,-3.919,2.777,,,H,A,1.52,-1.2,1.521,,71.59,AHH,-1.54633,0.100394,0.00458834,0.355135 beta-lactamase_625_L284W,beta-lactamase_625_284,TEM-1,beta-lactamase_625,P62593,0.355136,NO,284,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.213352,0.0686156,0.355136 beta-lactamase_625_T179I,beta-lactamase_625_179,TEM-1,beta-lactamase_625,P62593,0.355147,NO,179,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.085,-3.69,2.605,,,E,B,0.22,-1.38,0.367,,73.08,PPH,-1.557,0.213352,0.00226045,0.355147 kka2_1:1_Y257D,kka2_1:1_257,Kka2,kka2_1:1,P00552,0.355168,NO,257,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-1.064,-4.006,2.942,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.520039,0.0148191,0.355168 kka2_1:2_L93Q,kka2_1:2_93,Kka2,kka2_1:2,P00552,0.355172,NO,93,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.815,-4.083,3.268,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.295029,0.00131498,0.355172 beta-lactamase_156_N274F,beta-lactamase_156_274,TEM-1,beta-lactamase_156,P62593,0.355209,NO,274,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.111618,0.0110418,0.355209 beta-lactamase_2500_L100R,beta-lactamase_2500_100,TEM-1,beta-lactamase_2500,P62593,0.35522,NO,100,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.218,-4.123,2.905,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.361275,0.00413885,0.35522 kka2_1:1_R253H,kka2_1:1_253,Kka2,kka2_1:1,P00552,0.355254,NO,253,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.356,-4.521,3.165,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.520039,0.0144195,0.355254 beta-lactamase_156_S233Y,beta-lactamase_156_233,TEM-1,beta-lactamase_156,P62593,0.355279,NO,233,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.886,-4.293,2.407,,0.016,E,B,0.27,-1.01,4.111,,77.62,BPO,-1.17267,0.111618,0.00311415,0.355279 beta-lactamase_2500_S241F,beta-lactamase_2500_241,TEM-1,beta-lactamase_2500,P62593,0.355302,NO,241,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.361275,0.00452736,0.355302 beta-lactamase_625_L218E,beta-lactamase_625_218,TEM-1,beta-lactamase_625,P62593,0.355337,NO,218,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.391,-3.611,2.22,,,I,b,0.55,-0.53,17.202,17.202,74.48,OHH,-1.58867,0.213352,0.00618274,0.355337 kka2_1:2_M116H,kka2_1:2_116,Kka2,kka2_1:2,P00552,0.355363,NO,116,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-2.482,-4.918,2.436,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.295029,0.00745147,0.355363 beta-lactamase_625_I244Q,beta-lactamase_625_244,TEM-1,beta-lactamase_625,P62593,0.355438,NO,244,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.555,-4.255,2.7,,,E,B,0.48,-0.84,2.061,,77.62,OHH,-1.385,0.213352,0.00605379,0.355438 kka2_1:2_L193V,kka2_1:2_193,Kka2,kka2_1:2,P00552,0.355439,NO,193,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.983,-3.044,2.061,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.295029,0.00480179,0.355439 kka2_1:1_R145N,kka2_1:1_145,Kka2,kka2_1:1,P00552,0.355494,NO,145,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.804,-3.787,1.983,,0.346,H,A,1.2,1.23,23.699,23.699,63.64,HBP,-1.88033,0.520039,0.00846663,0.355494 beta-lactamase_2500_Y103E,beta-lactamase_2500_103,TEM-1,beta-lactamase_2500,P62593,0.355514,NO,103,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-1.33,-3.564,2.234,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.361275,0.00443048,0.355514 kka2_1:1_P98Y,kka2_1:1_98,Kka2,kka2_1:1,P00552,0.355522,NO,98,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.526,-4.481,2.955,,0.391,S,B,0.52,-0.65,1.521,,63.26,HOO,-1.19167,0.520039,0.00622754,0.355522 beta-lactamase_V257E,beta-lactamase_257,TEM-1,beta-lactamase,P62593,0.355568,NO,257,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.533,-3.799,2.266,5.31999,,E,B,0.96,-0.7,1.463,,58.74,HHH,-1.70967,0.221079,0.00756629,0.355568 kka2_1:1_L19F,kka2_1:1_19,Kka2,kka2_1:1,P00552,0.355779,NO,19,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.254,-2.137,0.883,,0.08,T,A,0.55,-0.26,17.165,17.165,65.53,BHH,-2.221,0.520039,0.00620703,0.355779 kka2_1:1_R258Q,kka2_1:1_258,Kka2,kka2_1:1,P00552,0.355855,NO,258,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.626,-2.106,0.48,,0.316,H,A,1.2,-0.85,7.485,7.485,53.03,HBH,-1.25933,0.520039,0.00983174,0.355855 beta-lactamase_625_R202D,beta-lactamase_625_202,TEM-1,beta-lactamase_625,P62593,0.355971,NO,202,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.292,-3.594,2.302,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.213352,0.00321899,0.355971 kka2_1:1_R217K,kka2_1:1_217,Kka2,kka2_1:1,P00552,0.356056,NO,217,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.158,-3.143,1.985,,0.252,T,A,1.2,-0.59,0.381,,52.27,ABH,-1.127,0.520039,0.0047191,0.356056 kka2_1:2_S104A,kka2_1:2_104,Kka2,kka2_1:2,P00552,0.356061,NO,104,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.436,-3.053,1.617,,0.536,T,A,0.27,-1.11,5.49,,63.64,HPP,-1.91433,0.295029,0.00555207,0.356061 kka2_1:1_E199M,kka2_1:1_199,Kka2,kka2_1:1,P00552,0.356103,NO,199,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.234,-4.802,2.568,,0.508,E,B,1.04,-0.43,3.012,,65.53,HAP,-2.133,0.520039,0.00854122,0.356103 kka2_1:1_L107F,kka2_1:1_107,Kka2,kka2_1:1,P00552,0.356174,NO,107,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.238,-3.877,2.639,,0.197,.,B,0.55,-1.1,3.542,,71.59,BHH,-2.143,0.520039,0.00561937,0.356174 kka2_1:1_L212H,kka2_1:1_212,Kka2,kka2_1:1,P00552,0.356198,NO,212,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.904,-4.956,4.052,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.520039,0.0031426,0.356198 kka2_1:1_L212Y,kka2_1:1_212,Kka2,kka2_1:1,P00552,0.356198,NO,212,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.904,-4.048,3.144,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.520039,0.0031426,0.356198 beta-lactamase_625_N130T,beta-lactamase_625_130,TEM-1,beta-lactamase_625,P62593,0.356242,NO,130,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-0.798,-3.196,2.398,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.213352,0.000683376,0.356242 beta-lactamase_N134W,beta-lactamase_134,TEM-1,beta-lactamase,P62593,0.356246,NO,134,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-0.879,-5.545,4.666,5.07245,0.138,H,A,0.09,-0.6,1.441,,53.15,HPH,-1.02233,0.221079,0.000644786,0.356246 beta-lactamase_2500_G240R,beta-lactamase_2500_240,TEM-1,beta-lactamase_2500,P62593,0.356269,NO,240,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.361275,0.00591201,0.356269 kka2_1:1_L123A,kka2_1:1_123,Kka2,kka2_1:1,P00552,0.356423,NO,123,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.888,-3.161,2.273,,0.007,H,A,0.55,-0.4,1.447,,48.86,BHB,-1.301,0.520039,0.00325188,0.356423 beta-lactamase_2500_A132T,beta-lactamase_2500_132,TEM-1,beta-lactamase_2500,P62593,0.356455,NO,132,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.9,-3.22,2.32,,,H,A,0.46,-0.93,8.408,,64.69,PHH,-1.138,0.361275,0.000962524,0.356455 kka2_1:4_R217A,kka2_1:4_217,Kka2,kka2_1:4,P00552,0.356492,NO,217,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.158,-3.215,2.057,,0.252,T,A,1.2,-0.59,2.074,,52.27,ABH,-1.127,0.168804,0.0047191,0.356492 beta-lactamase_625_A235H,beta-lactamase_625_235,TEM-1,beta-lactamase_625,P62593,0.356494,NO,235,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.266,-4.769,3.503,,0.32,E,B,0.46,-0.86,0.281,,50,OHO,-0.89,0.213352,0.00493474,0.356494 kka2_1:8_M116Q,kka2_1:8_116,Kka2,kka2_1:8,P00552,0.356538,NO,116,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-2.482,-4.256,1.774,,,H,A,1.59,-0.88,4.659,,71.59,HHH,-1.63867,0.100394,0.00745147,0.356538 kka2_1:8_M116Q,kka2_1:8_116,Kka2,kka2_1:8,P00552,0.356538,NO,116,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-2.482,-4.256,1.774,,,H,A,1.59,-0.88,4.659,,71.59,HHH,-1.63867,0.100394,0.00745147,0.356538 kka2_1:1_L223N,kka2_1:1_223,Kka2,kka2_1:1,P00552,0.356568,NO,223,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.861,-4.196,3.335,,,H,A,0.55,-1.24,1.268,,50,HHH,-0.854333,0.520039,0.00253574,0.356568 kka2_1:2_V153P,kka2_1:2_153,Kka2,kka2_1:2,P00552,0.356578,NO,153,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.092,-4.027,2.935,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.295029,0.00501119,0.356578 beta-lactamase_625_L188Q,beta-lactamase_625_188,TEM-1,beta-lactamase_625,P62593,0.356579,NO,188,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.166,-4.055,2.889,,,H,A,0.55,-0.3,2.982,,60.14,PHB,-1.47033,0.213352,0.00295687,0.356579 beta-lactamase_156_A132E,beta-lactamase_156_132,TEM-1,beta-lactamase_156,P62593,0.356591,NO,132,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.9,-3.484,2.584,,,H,A,0.46,-0.93,10.621,,64.69,PHH,-1.138,0.111618,0.000962524,0.356591 kka2_1:1_M116A,kka2_1:1_116,Kka2,kka2_1:1,P00552,0.356657,NO,116,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-2.482,-2.16,-0.322,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.520039,0.00745147,0.356657 beta-lactamase_625_V72W,beta-lactamase_625_72,TEM-1,beta-lactamase_625,P62593,0.356734,NO,72,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.658,-3.279,1.621,,,H,A,0.44,-1.03,0.981,,65.73,BHH,-1.32167,0.213352,0.00501194,0.356734 kka2_1:4_W91N,kka2_1:4_91,Kka2,kka2_1:4,P00552,0.356973,NO,91,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-1.178,-4.186,3.008,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.168804,0.00358653,0.356973 beta-lactamase_625_V117K,beta-lactamase_625_117,TEM-1,beta-lactamase_625,P62593,0.357016,NO,117,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.53,-3.844,2.314,,,H,A,0.44,-0.34,1.23,,65.03,PHB,-1.741,0.213352,0.00467906,0.357016 kka2_1:2_L102Q,kka2_1:2_102,Kka2,kka2_1:2,P00552,0.357025,NO,102,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.804,-4.12,3.316,,,T,A,1.59,-1.17,4.258,,42.42,AHH,-1.398,0.295029,0.00201332,0.357025 beta-lactamase_625_A34K,beta-lactamase_625_34,TEM-1,beta-lactamase_625,P62593,0.357055,NO,34,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.059,-3.736,1.677,,,H,A,0.46,-0.54,3.614,,73.78,AHA,-1.74967,0.213352,0.00407913,0.357055 beta-lactamase_625_M184T,beta-lactamase_625_184,TEM-1,beta-lactamase_625,P62593,0.357104,NO,184,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.593,-2.764,1.171,,,H,A,0.55,-0.87,2.765,,62.94,HHH,-1.41,0.213352,0.00356019,0.357104 kka2_1:8_D261E,kka2_1:8_261,Kka2,kka2_1:8,P00552,0.35712,NO,261,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.708,-2.793,2.085,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.100394,0.0224846,0.35712 kka2_1:8_D261E,kka2_1:8_261,Kka2,kka2_1:8,P00552,0.35712,NO,261,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.708,-2.793,2.085,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.100394,0.0224846,0.35712 beta-lactamase_625_L73W,beta-lactamase_625_73,TEM-1,beta-lactamase_625,P62593,0.357228,NO,73,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.507,-5.171,3.664,,,H,A,0.55,-0.64,2.933,,67.83,HHH,-1.487,0.213352,0.00488983,0.357228 kka2_1:8_G30W,kka2_1:8_30,Kka2,kka2_1:8,P00552,0.357237,NO,30,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.596,-5.126,4.53,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.100394,0.00159208,0.357237 kka2_1:8_G30W,kka2_1:8_30,Kka2,kka2_1:8,P00552,0.357237,NO,30,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.596,-5.126,4.53,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.100394,0.00159208,0.357237 kka2_1:8_L39K,kka2_1:8_39,Kka2,kka2_1:8,P00552,0.357237,NO,39,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.223,-3.871,2.648,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.100394,0.00493618,0.357237 kka2_1:8_L39K,kka2_1:8_39,Kka2,kka2_1:8,P00552,0.357237,NO,39,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.223,-3.871,2.648,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.100394,0.00493618,0.357237 kka2_1:1_A247Y,kka2_1:1_247,Kka2,kka2_1:1,P00552,0.357313,NO,247,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.459,-4.278,1.819,,1.01,S,A,0.46,0.65,7.731,7.731,92.05,HHH,-2.197,0.520039,0.0102428,0.357313 beta-lactamase_2500_R189P,beta-lactamase_2500_189,TEM-1,beta-lactamase_2500,P62593,0.357353,NO,189,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.844,-3.964,2.12,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.361275,0.0050699,0.357353 kka2_1:2_A41P,kka2_1:2_41,Kka2,kka2_1:2,P00552,0.357486,NO,41,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.879,-2.834,0.955,,0.184,.,B,0.46,-0.96,24.451,24.451,64.39,PHP,-2.477,0.295029,0.00543332,0.357486 beta-lactamase_2500_V117H,beta-lactamase_2500_117,TEM-1,beta-lactamase_2500,P62593,0.357533,NO,117,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.53,-4.89,3.36,,,H,A,0.44,-0.34,1.23,,65.03,PHB,-1.741,0.361275,0.00467906,0.357533 hsp90_F583R,hsp90_583,hsp90,hsp90,P02829,0.357539,NO,583,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-3.22,-3.086,0,5.28185,1.112,S,l,1.1,0.87,,,,PHO,-3.003,0.368192,0.000222939,0.357539 beta-lactamase_625_A34E,beta-lactamase_625_34,TEM-1,beta-lactamase_625,P62593,0.35757,NO,34,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.059,-3.743,1.684,,,H,A,0.46,-0.54,3.614,,73.78,AHA,-1.74967,0.213352,0.00407913,0.35757 kka2_1:2_G201E,kka2_1:2_201,Kka2,kka2_1:2,P00552,0.357581,NO,201,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.56,-2.596,1.036,,0.149,T,l,0.29,-0.57,16.092,16.092,52.65,POB,-1.92233,0.295029,0.00820117,0.357581 beta-lactamase_625_W288P,beta-lactamase_625_288,TEM-1,beta-lactamase_625,P62593,0.357589,NO,288,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,,,,,,,,,,,,,BHO,,0.213352,,0.357589 beta-lactamase_625_S104F,beta-lactamase_625_104,TEM-1,beta-lactamase_625,P62593,0.357696,NO,104,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.015,-4.127,3.112,,0.04,,b,0.27,0.57,1.76,,63.29,HPO,-1.05267,0.213352,0.00218083,0.357696 kka2_1:4_F37R,kka2_1:4_37,Kka2,kka2_1:4,P00552,0.357736,NO,37,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.427,-4.151,2.724,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.168804,0.00586193,0.357736 beta-lactamase_156_L136N,beta-lactamase_156_136,TEM-1,beta-lactamase_156,P62593,0.357784,NO,136,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.232,-4.217,2.985,,,H,A,0.55,-0.34,1.04,,48.95,HHH,-1.088,0.111618,0.00442304,0.357784 beta-lactamase_625_I125S,beta-lactamase_625_125,TEM-1,beta-lactamase_625,P62593,0.357862,NO,125,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.441,-2.843,1.402,,,H,A,0.48,-0.7,2.034,,63.29,HHP,-1.248,0.213352,0.00383964,0.357862 kka2_1:1_A224Y,kka2_1:1_224,Kka2,kka2_1:1,P00552,0.357887,NO,224,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.977,-4.257,3.28,,,H,A,0.46,-1.26,1.725,,63.64,HHP,-1.41033,0.520039,0.00352047,0.357887 kka2_1:1_I2E,kka2_1:1_2,Kka2,kka2_1:1,P00552,0.357914,NO,2,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.787,-3.519,1.732,,,,,,,2.329,,71.59,HHA,-1.92433,0.520039,0.00246644,0.357914 beta-lactamase_156_G236W,beta-lactamase_156_236,TEM-1,beta-lactamase_156,P62593,0.358017,NO,236,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.784,-5.189,4.405,,0.241,,b,0.29,-0.59,1.883,,64.69,HOO,-1.025,0.111618,0.00162372,0.358017 kka2_1:1_D101H,kka2_1:1_101,Kka2,kka2_1:1,P00552,0.358039,NO,101,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.028,-4.537,3.509,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.520039,0.00423361,0.358039 beta-lactamase_2500_I45H,beta-lactamase_2500_45,TEM-1,beta-lactamase_2500,P62593,0.358041,NO,45,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-2.421,-3.408,0.987,,,E,B,0.48,-0.3,3.793,,77.62,HHA,-2.30267,0.361275,0.00452842,0.358041 Pab1_A182R,Pab1_182,Pab1,Pab1,P04147,0.358116,NO,182,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.013,-3.525,2.512,,,H,A,0.17,0.79,,,,AHH,-1.36067,0.175299,0.000289034,0.358116 kka2_1:1_E3V,kka2_1:1_3,Kka2,kka2_1:1,P00552,0.358282,NO,3,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.199,-3.503,1.304,,,,,,,3.435,,92.05,HAP,-2.11567,0.520039,0.00267607,0.358282 kka2_1:8_D220C,kka2_1:8_220,Kka2,kka2_1:8,P00552,0.358282,NO,220,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.787,-5.083,4.296,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.100394,0.00158066,0.358282 kka2_1:8_D220C,kka2_1:8_220,Kka2,kka2_1:8,P00552,0.358282,NO,220,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.787,-5.083,4.296,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.100394,0.00158066,0.358282 kka2_1:1_E142D,kka2_1:1_142,Kka2,kka2_1:1,P00552,0.358284,NO,142,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.221,-3.049,0.828,,0.471,H,A,1.52,0.85,3.626,,65.53,HAB,-2.08033,0.520039,0.00748883,0.358284 kka2_1:4_W69H,kka2_1:4_69,Kka2,kka2_1:4,P00552,0.358289,NO,69,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-0.859,-4.594,3.735,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.168804,0.0012874,0.358289 beta-lactamase_G236H,beta-lactamase_236,TEM-1,beta-lactamase,P62593,0.358467,NO,236,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.784,-4.704,3.92,4.7915,0.241,,b,0.23,-0.59,1.883,,64.69,HOA,-1.36933,0.221079,0.00162372,0.358467 kka2_1:2_A237L,kka2_1:2_237,Kka2,kka2_1:2,P00552,0.35847,NO,237,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.12,-2.076,-0.044,,0.068,H,A,0.46,-0.71,2.369,,92.05,HHA,-2.10433,0.295029,0.012257,0.35847 beta-lactamase_2500_P105W,beta-lactamase_2500_105,TEM-1,beta-lactamase_2500,P62593,0.35849,NO,105,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.813,-5.545,4.732,,0.226,T,A,0.52,0.8,3.1,,63.29,POH,-1.01533,0.361275,0.0011981,0.35849 kka2_1:1_L126I,kka2_1:1_126,Kka2,kka2_1:1,P00552,0.358501,NO,126,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.246,-2.028,0.782,,0.285,S,B,0.55,0.12,0.302,,51.89,PHA,-1.744,0.520039,0.0066485,0.358501 kka2_1:4_D101F,kka2_1:4_101,Kka2,kka2_1:4,P00552,0.358513,NO,101,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.028,-4.345,3.317,,0.213,E,B,0.75,-1.24,8.707,,63.64,PAH,-1.534,0.168804,0.00423361,0.358513 kka2_1:2_S204H,kka2_1:2_204,Kka2,kka2_1:2,P00552,0.358574,NO,204,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.353,-4.723,3.37,,0.144,E,A,0.27,-1.2,2.442,,65.53,HPO,-0.953333,0.295029,0.00881794,0.358574 beta-lactamase_2500_K30D,beta-lactamase_2500_30,TEM-1,beta-lactamase_2500,P62593,0.358595,NO,30,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-2.307,-3.567,1.26,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.361275,0.00448593,0.358595 kka2_1:1_R145M,kka2_1:1_145,Kka2,kka2_1:1,P00552,0.358599,NO,145,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.804,-4.748,2.944,,0.346,H,A,1.2,1.23,23.699,23.699,63.64,HBP,-1.88033,0.520039,0.00846663,0.358599 kka2_1:1_L107S,kka2_1:1_107,Kka2,kka2_1:1,P00552,0.358612,NO,107,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.238,-3.641,2.403,,0.197,.,B,0.55,-1.1,3.542,,71.59,BHH,-2.143,0.520039,0.00561937,0.358612 kka2_1:8_D261A,kka2_1:8_261,Kka2,kka2_1:8,P00552,0.35863,NO,261,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.708,-3.331,2.623,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.100394,0.0224846,0.35863 kka2_1:8_D261A,kka2_1:8_261,Kka2,kka2_1:8,P00552,0.35863,NO,261,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.708,-3.331,2.623,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.100394,0.0224846,0.35863 kka2_1:1_R143F,kka2_1:1_143,Kka2,kka2_1:1,P00552,0.358705,NO,143,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.525,-4.3,1.775,,0.325,H,A,0.16,1.22,3.6,,65.53,ABH,-1.86833,0.520039,0.00662247,0.358705 beta-lactamase_625_D212Y,beta-lactamase_625_212,TEM-1,beta-lactamase_625,P62593,0.358734,NO,212,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.624,-4.398,2.774,,0.037,,b,0.75,-0.58,1.516,,74.48,HAB,-1.77667,0.213352,0.00644302,0.358734 kka2_1:1_L93Q,kka2_1:1_93,Kka2,kka2_1:1,P00552,0.358779,NO,93,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.815,-4.083,3.268,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.520039,0.00131498,0.358779 kka2_1:1_L174Y,kka2_1:1_174,Kka2,kka2_1:1,P00552,0.358798,NO,174,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.952,-4.056,3.104,,,H,A,0.55,-0.31,13.276,13.276,51.89,BHB,-2.08533,0.520039,0.00438501,0.358798 kka2_1:2_C209M,kka2_1:2_209,Kka2,kka2_1:2,P00552,0.358807,NO,209,C,M,CM,Special,Hydrophobic,5.07,5.74,0.67,196,121,149,28,108.5,162.9,54.4,-0.906,-4.438,3.532,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.295029,0.00260862,0.358807 kka2_1:8_I221G,kka2_1:8_221,Kka2,kka2_1:8,P00552,0.358844,NO,221,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.739,-3.884,2.145,,,H,A,1.52,-1.15,1.599,,71.59,AHH,-1.08367,0.100394,0.00945908,0.358844 kka2_1:8_I221G,kka2_1:8_221,Kka2,kka2_1:8,P00552,0.358844,NO,221,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.739,-3.884,2.145,,,H,A,1.52,-1.15,1.599,,71.59,AHH,-1.08367,0.100394,0.00945908,0.358844 kka2_1:1_R143K,kka2_1:1_143,Kka2,kka2_1:1,P00552,0.35908,NO,143,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.525,-3.061,0.536,,0.325,H,A,0.16,1.22,3.6,,65.53,ABH,-1.86833,0.520039,0.00662247,0.35908 beta-lactamase_625_N134V,beta-lactamase_625_134,TEM-1,beta-lactamase_625,P62593,0.359167,NO,134,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-0.879,-3.751,2.872,,0.138,H,A,0.61,-0.6,3.776,,53.15,HPH,-1.02233,0.213352,0.000644786,0.359167 kka2_1:1_F203R,kka2_1:1_203,Kka2,kka2_1:1,P00552,0.359235,NO,203,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-0.911,-4.185,3.274,,0.26,E,B,0.58,-0.92,7.323,,63.64,BHP,-1.34167,0.520039,0.00318738,0.359235 kka2_1:1_G201F,kka2_1:1_201,Kka2,kka2_1:1,P00552,0.359263,NO,201,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.56,-4.498,2.938,,0.149,T,l,0.29,-0.57,16.092,16.092,52.65,POB,-1.92233,0.520039,0.00820117,0.359263 beta-lactamase_2500_S266F,beta-lactamase_2500_266,TEM-1,beta-lactamase_2500,P62593,0.359295,NO,266,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.361275,0.0140785,0.359295 kka2_1:2_C209Y,kka2_1:2_209,Kka2,kka2_1:2,P00552,0.359306,NO,209,C,Y,CY,Special,Hydrophobic,5.07,5.66,0.59,194,121,181,60,108.5,193.6,85.1,-0.906,-4.189,3.283,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.295029,0.00260862,0.359306 kka2_1:1_G233I,kka2_1:1_233,Kka2,kka2_1:1,P00552,0.359316,NO,233,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.748,-4.263,3.515,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.520039,0.00232366,0.359316 beta-lactamase_625_I285P,beta-lactamase_625_285,TEM-1,beta-lactamase_625,P62593,0.359378,NO,285,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.213352,0.101555,0.359378 beta-lactamase_2500_K190P,beta-lactamase_2500_190,TEM-1,beta-lactamase_2500,P62593,0.359421,NO,190,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.994,-3.086,1.092,,0.371,H,A,2.34,0.16,29.753,29.753,77.62,BBH,-1.64167,0.361275,0.00574527,0.359421 kka2_1:1_A13W,kka2_1:1_13,Kka2,kka2_1:1,P00552,0.359425,NO,13,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.248,-3.869,1.621,,0.689,G,A,0.46,0.99,25.015,25.015,92.05,OHH,-1.646,0.520039,0.00784241,0.359425 beta-lactamase_2500_I229A,beta-lactamase_2500_229,TEM-1,beta-lactamase_2500,P62593,0.35951,NO,229,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.267,-3.077,1.81,,0.083,E,B,0.48,-0.76,3.875,,50,HHH,-1.58767,0.361275,0.00477249,0.35951 beta-lactamase_2500_S266I,beta-lactamase_2500_266,TEM-1,beta-lactamase_2500,P62593,0.359511,NO,266,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.361275,0.0140785,0.359511 kka2_1:1_V153W,kka2_1:1_153,Kka2,kka2_1:1,P00552,0.3596,NO,153,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.092,-5.429,4.337,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.520039,0.00501119,0.3596 kka2_1:1_G21H,kka2_1:1_21,Kka2,kka2_1:1,P00552,0.359607,NO,21,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.368,-2.564,1.196,,0.586,T,l,0.29,-0.75,10.291,10.291,71.59,HOH,-2.10167,0.520039,0.00709648,0.359607 WW_domain_W177L,WW_domain_177,Yap65,WW_domain,P46937,0.359693,NO,177,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-1.198,-3.135,1.937,5.18137,,,,,,,,,OHA,-1.197,0.153962,0.00198549,0.359693 beta-lactamase_625_W227M,beta-lactamase_625_227,TEM-1,beta-lactamase_625,P62593,0.359728,NO,227,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-0.982,-4.54,3.558,,0.272,,B,0.47,-0.29,2.533,,74.48,OHH,-1.595,0.213352,0.00226019,0.359728 kka2_1:1_E169C,kka2_1:1_169,Kka2,kka2_1:1,P00552,0.359733,NO,169,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.996,-5.197,3.201,,0.422,H,A,1.04,0.3,7.546,7.546,65.53,HAH,-1.755,0.520039,0.00730086,0.359733 kka2_1:1_A150K,kka2_1:1_150,Kka2,kka2_1:1,P00552,0.359769,NO,150,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.949,-3.494,2.545,,0.544,T,A,0.46,1.34,2.333,,63.26,AHO,-1.272,0.520039,0.0045009,0.359769 kka2_1:8_L174H,kka2_1:8_174,Kka2,kka2_1:8,P00552,0.359831,NO,174,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.952,-4.968,4.016,,,H,A,1.59,-0.31,1.204,,51.89,BHB,-2.08533,0.100394,0.00438501,0.359831 kka2_1:8_L174H,kka2_1:8_174,Kka2,kka2_1:8,P00552,0.359831,NO,174,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.952,-4.968,4.016,,,H,A,1.59,-0.31,1.204,,51.89,BHB,-2.08533,0.100394,0.00438501,0.359831 kka2_1:1_G10E,kka2_1:1_10,Kka2,kka2_1:1,P00552,0.359834,NO,10,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.921,-2.456,0.535,,,,,,,1.862,,71.59,HOP,-2.10733,0.520039,0.00289233,0.359834 kka2_1:8_A117P,kka2_1:8_117,Kka2,kka2_1:8,P00552,0.359902,NO,117,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.828,-3.747,2.919,,,H,A,1.04,-0.78,0.755,,45.83,HHA,-1.79333,0.100394,0.00282984,0.359902 kka2_1:8_A117P,kka2_1:8_117,Kka2,kka2_1:8,P00552,0.359902,NO,117,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.828,-3.747,2.919,,,H,A,1.04,-0.78,0.755,,45.83,HHA,-1.79333,0.100394,0.00282984,0.359902 kka2_1:1_W15V,kka2_1:1_15,Kka2,kka2_1:1,P00552,0.359905,NO,15,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-1.392,-3.309,1.917,,0.01,G,A,0.47,0.15,20.149,20.149,52.27,HHH,-2.10533,0.520039,0.00585505,0.359905 kka2_1:1_F37G,kka2_1:1_37,Kka2,kka2_1:1,P00552,0.359939,NO,37,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.427,-3.622,2.195,,0.219,E,B,0.58,-0.25,18.64,18.64,64.39,HHB,-1.17733,0.520039,0.00586193,0.359939 kka2_1:1_P109N,kka2_1:1_109,Kka2,kka2_1:1,P00552,0.359944,NO,109,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.412,-3.924,2.512,,0.376,H,A,0.52,-1.25,18.506,18.506,65.53,HOH,-1.84567,0.520039,0.0070929,0.359944 kka2_1:2_D127I,kka2_1:2_127,Kka2,kka2_1:2,P00552,0.359957,NO,127,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.364,-4.127,2.763,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.295029,0.00660501,0.359957 beta-lactamase_0_L150K,beta-lactamase_0_150,TEM-1,beta-lactamase_0,P62593,0.359972,NO,150,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.326,-3.711,2.385,,,H,A,0.55,-0.2,2.128,,62.94,HHB,-1.86167,0.0500837,0.00463171,0.359972 beta-lactamase_2500_T116Y,beta-lactamase_2500_116,TEM-1,beta-lactamase_2500,P62593,0.359974,NO,116,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.28,-4.295,3.015,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.361275,0.00336175,0.359974 beta-lactamase_625_D174I,beta-lactamase_625_174,TEM-1,beta-lactamase_625,P62593,0.359988,NO,174,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.738,-4.01,3.272,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.213352,0.00125633,0.359988 kka2_1:8_D261R,kka2_1:8_261,Kka2,kka2_1:8,P00552,0.360133,NO,261,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.708,-3.961,3.253,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.100394,0.0224846,0.360133 kka2_1:8_D261R,kka2_1:8_261,Kka2,kka2_1:8,P00552,0.360133,NO,261,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.708,-3.961,3.253,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.100394,0.0224846,0.360133 kka2_1:4_P45F,kka2_1:4_45,Kka2,kka2_1:4,P00552,0.360146,NO,45,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.774,-4.506,2.732,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.168804,0.00590481,0.360146 kka2_1:1_K138E,kka2_1:1_138,Kka2,kka2_1:1,P00552,0.36015,NO,138,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-2.5,-1.783,-0.717,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.520039,0.00628542,0.36015 kka2_1:4_H124Y,kka2_1:4_124,Kka2,kka2_1:4,P00552,0.360289,NO,124,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-0.84,-3.291,2.451,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.168804,0.00211296,0.360289 kka2_1:1_A176D,kka2_1:1_176,Kka2,kka2_1:1,P00552,0.360305,NO,176,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.621,-2.955,1.334,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.520039,0.0083587,0.360305 beta-lactamase_A246R,beta-lactamase_246,TEM-1,beta-lactamase,P62593,0.36037,NO,246,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.121,-4.154,2.033,4.78979,0.01,E,B,0.52,-1.01,1.26,,73.78,HHH,-1.55633,0.221079,0.00569458,0.36037 beta-lactamase_Y260A,beta-lactamase_260,TEM-1,beta-lactamase,P62593,0.360383,NO,260,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-1.101,-3.344,2.243,5.50878,,E,B,0.73,-1.04,0.865,,60.49,HHP,-1.83433,0.221079,0.00471757,0.360383 kka2_1:1_K175E,kka2_1:1_175,Kka2,kka2_1:1,P00552,0.360645,NO,175,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-2.897,-2.454,-0.443,,0.579,H,A,1.3,0.51,9.33,9.33,71.59,HBH,-1.82333,0.520039,0.00693093,0.360645 kka2_1:1_A65G,kka2_1:1_65,Kka2,kka2_1:1,P00552,0.360788,NO,65,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.744,-2.917,1.173,,0.437,H,A,0.46,-0.39,3.012,,63.64,HHB,-1.38733,0.520039,0.00709258,0.360788 kka2_1:4_A237N,kka2_1:4_237,Kka2,kka2_1:4,P00552,0.360797,NO,237,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.12,-4.131,2.011,,0.068,H,A,0.46,-0.71,2.444,,92.05,HHA,-2.10433,0.168804,0.012257,0.360797 kka2_1:4_G43I,kka2_1:4_43,Kka2,kka2_1:4,P00552,0.360797,NO,43,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.587,-4.201,2.614,,0.862,T,l,0.75,-0.67,2.247,,63.26,POB,-2.18533,0.168804,0.0071925,0.360797 kka2_1:1_D134A,kka2_1:1_134,Kka2,kka2_1:1,P00552,0.360874,NO,134,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.969,-3.306,2.337,,0.421,B,B,0.75,0.31,2.329,,49.62,HAB,-1.057,0.520039,0.00270812,0.360874 Pab1_S154Y,Pab1_154,Pab1,Pab1,P04147,0.3609,NO,154,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.146,-3.98,2.834,,0.208,E,B,0.1,-0.75,,,,HPP,-1.408,0.175299,0.000319331,0.3609 kka2_1:4_G233I,kka2_1:4_233,Kka2,kka2_1:4,P00552,0.360921,NO,233,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.748,-4.263,3.515,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.168804,0.00232366,0.360921 kka2_1:1_E149A,kka2_1:1_149,Kka2,kka2_1:1,P00552,0.360937,NO,149,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.994,-2.44,0.446,,0.674,H,A,1.04,1.63,3.671,,71.59,HAH,-1.59667,0.520039,0.00803343,0.360937 kka2_1:8_I228G,kka2_1:8_228,Kka2,kka2_1:8,P00552,0.36094,NO,228,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.142,-3.869,2.727,,,H,A,1.52,-1.2,1.521,,71.59,AHH,-1.54633,0.100394,0.00458834,0.36094 kka2_1:8_I228G,kka2_1:8_228,Kka2,kka2_1:8,P00552,0.36094,NO,228,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.142,-3.869,2.727,,,H,A,1.52,-1.2,1.521,,71.59,AHH,-1.54633,0.100394,0.00458834,0.36094 beta-lactamase_625_R242F,beta-lactamase_625_242,TEM-1,beta-lactamase_625,P62593,0.360953,NO,242,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.213352,0.00452879,0.360953 kka2_1:1_R239Y,kka2_1:1_239,Kka2,kka2_1:1,P00552,0.361046,NO,239,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.949,-4.327,1.378,,0.15,H,A,1.2,-0.31,0.477,,71.59,ABH,-2.23,0.520039,0.00835326,0.361046 kka2_1:2_A215D,kka2_1:2_215,Kka2,kka2_1:2,P00552,0.361095,NO,215,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.968,-3.663,2.695,,0.039,E,B,0.46,-0.59,2.137,,50.38,HHA,-1.00467,0.295029,0.00529129,0.361095 kka2_1:2_A215H,kka2_1:2_215,Kka2,kka2_1:2,P00552,0.361095,NO,215,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.968,-4.735,3.767,,0.039,E,B,0.46,-0.59,2.137,,50.38,HHA,-1.00467,0.295029,0.00529129,0.361095 kka2_1:2_E230P,kka2_1:2_230,Kka2,kka2_1:2,P00552,0.3611,NO,230,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.672,-4.133,1.461,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.295029,0.00920051,0.3611 kka2_1:4_V49G,kka2_1:4_49,Kka2,kka2_1:4,P00552,0.361108,NO,49,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.614,-3.739,2.125,,,E,B,0.44,-0.77,1.233,,64.39,HHB,-1.3,0.168804,0.00615685,0.361108 kka2_1:2_V75W,kka2_1:2_75,Kka2,kka2_1:2,P00552,0.361133,NO,75,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-2.06,-5.286,3.226,,0.042,.,B,0.44,-0.2,2.815,,71.59,OHO,-1.563,0.295029,0.00693733,0.361133 kka2_1:1_L243N,kka2_1:1_243,Kka2,kka2_1:1,P00552,0.361161,NO,243,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-2.651,-3.218,0.567,,0.277,H,A,0.55,-0.67,4.334,,92.05,HHH,-2.03767,0.520039,0.00884927,0.361161 beta-lactamase_625_S241V,beta-lactamase_625_241,TEM-1,beta-lactamase_625,P62593,0.361213,NO,241,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.213352,0.00452736,0.361213 beta-lactamase_625_N168E,beta-lactamase_625_168,TEM-1,beta-lactamase_625,P62593,0.361293,NO,168,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-1.029,-3.29,2.261,,0.113,G,A,0.61,-0.4,1.014,,44.41,HPA,-1.13233,0.213352,0.00288667,0.361293 kka2_1:4_E63G,kka2_1:4_63,Kka2,kka2_1:4,P00552,0.361349,NO,63,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-0.762,-3.386,2.624,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.168804,0.00118399,0.361349 beta-lactamase_156_L188E,beta-lactamase_156_188,TEM-1,beta-lactamase_156,P62593,0.361354,NO,188,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.166,-2.834,1.668,,,H,A,0.55,-0.3,1.574,,60.14,PHB,-1.47033,0.111618,0.00295687,0.361354 kka2_1:1_H106A,kka2_1:1_106,Kka2,kka2_1:1,P00552,0.361378,NO,106,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-3.13,-2.399,-0.731,,1.065,.,a,0.17,-0.95,2.53,,71.59,PBH,-2.10433,0.520039,0.00730778,0.361378 kka2_1:4_R253P,kka2_1:4_253,Kka2,kka2_1:4,P00552,0.361405,NO,253,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.356,-3.924,2.568,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.168804,0.0144195,0.361405 kka2_1:4_N195H,kka2_1:4_195,Kka2,kka2_1:4,P00552,0.361469,NO,195,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-0.836,-4.094,3.258,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.168804,0.00276134,0.361469 beta-lactamase_2500_L218A,beta-lactamase_2500_218,TEM-1,beta-lactamase_2500,P62593,0.361481,NO,218,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.391,-3.175,1.784,,,I,b,0.55,-0.53,9.151,9.151,74.48,OHH,-1.58867,0.361275,0.00618274,0.361481 kka2_1:8_L70Q,kka2_1:8_70,Kka2,kka2_1:8,P00552,0.361515,NO,70,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.017,-4.149,3.132,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.100394,0.00411884,0.361515 kka2_1:8_L70Q,kka2_1:8_70,Kka2,kka2_1:8,P00552,0.361515,NO,70,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.017,-4.149,3.132,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.100394,0.00411884,0.361515 kka2_1:2_G213K,kka2_1:2_213,Kka2,kka2_1:2,P00552,0.361516,NO,213,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.596,-3.71,3.114,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.295029,0.00187654,0.361516 kka2_1:2_G213P,kka2_1:2_213,Kka2,kka2_1:2,P00552,0.361516,NO,213,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.596,-3.908,3.312,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.295029,0.00187654,0.361516 beta-lactamase_W286D,beta-lactamase_286,TEM-1,beta-lactamase,P62593,0.361521,NO,286,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-1.111,-3.961,2.85,6.64456,0.492,,?,0.01,0.6,,,,BHX,-1.478,0.221079,,0.361521 beta-lactamase_625_D83F,beta-lactamase_625_83,TEM-1,beta-lactamase_625,P62593,0.361553,NO,83,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.066,-4.344,3.278,,0.354,H,A,0.75,0.22,0.239,,48.95,HAH,-1.34733,0.213352,0.00205968,0.361553 beta-lactamase_156_S233H,beta-lactamase_156_233,TEM-1,beta-lactamase_156,P62593,0.36159,NO,233,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.886,-4.67,2.784,,0.016,E,B,0.27,-1.01,4.111,,77.62,BPO,-1.17267,0.111618,0.00311415,0.36159 beta-lactamase_N168P,beta-lactamase_168,TEM-1,beta-lactamase,P62593,0.36162,NO,168,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-1.029,-3.858,2.829,5.42128,0.113,G,A,0.09,-0.4,1.211,,44.41,HPA,-1.13233,0.221079,0.00288667,0.36162 kka2_1:1_D250S,kka2_1:1_250,Kka2,kka2_1:1,P00552,0.361628,NO,250,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.015,-2.641,1.626,,0.274,.,b,0.75,-0.46,4.177,,51.89,OAP,-1.83933,0.520039,0.0177103,0.361628 kka2_1:1_H139S,kka2_1:1_139,Kka2,kka2_1:1,P00552,0.361658,NO,139,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-2.809,-2.678,-0.131,,0.471,H,A,0.17,0.68,1.153,,63.64,BBB,-2.22,0.520039,0.00734779,0.361658 kka2_1:1_K138L,kka2_1:1_138,Kka2,kka2_1:1,P00552,0.36167,NO,138,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-2.5,-3.647,1.147,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.520039,0.00628542,0.36167 kka2_1:1_H135W,kka2_1:1_135,Kka2,kka2_1:1,P00552,0.361673,NO,135,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-1.331,-5.284,3.953,,0.071,.,a,0.17,0.65,3.574,,53.03,ABP,-1.77367,0.520039,0.00532566,0.361673 beta-lactamase_2500_T131R,beta-lactamase_2500_131,TEM-1,beta-lactamase_2500,P62593,0.361698,NO,131,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.328,-2.888,1.56,,,H,A,0.22,-0.69,3.048,,67.48,PPH,-1.00867,0.361275,0.00345886,0.361698 kka2_1:2_L174Y,kka2_1:2_174,Kka2,kka2_1:2,P00552,0.361728,NO,174,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.952,-4.056,3.104,,,H,A,1.59,-0.31,8.521,,51.89,BHB,-2.08533,0.295029,0.00438501,0.361728 kka2_1:8_Y257G,kka2_1:8_257,Kka2,kka2_1:8,P00552,0.361765,NO,257,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-1.064,-3.67,2.606,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.100394,0.0148191,0.361765 kka2_1:8_Y257G,kka2_1:8_257,Kka2,kka2_1:8,P00552,0.361765,NO,257,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-1.064,-3.67,2.606,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.100394,0.0148191,0.361765 kka2_1:1_D134F,kka2_1:1_134,Kka2,kka2_1:1,P00552,0.361771,NO,134,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.969,-4.314,3.345,,0.421,B,B,0.75,0.31,2.329,,49.62,HAB,-1.057,0.520039,0.00270812,0.361771 beta-lactamase_A215D,beta-lactamase_215,TEM-1,beta-lactamase,P62593,0.361809,NO,215,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.503,-3.621,2.118,4.82164,,,a,0.75,-0.93,3.583,,74.48,HHO,-1.42633,0.221079,0.00544007,0.361809 kka2_1:2_H135P,kka2_1:2_135,Kka2,kka2_1:2,P00552,0.361818,NO,135,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-1.331,-3.963,2.632,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.295029,0.00532566,0.361818 beta-lactamase_625_G236Q,beta-lactamase_625_236,TEM-1,beta-lactamase_625,P62593,0.361851,NO,236,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.784,-4.093,3.309,,0.241,,b,0.29,-0.59,3.506,,64.69,HOO,-1.025,0.213352,0.00162372,0.361851 beta-lactamase_156_T69E,beta-lactamase_156_69,TEM-1,beta-lactamase_156,P62593,0.361889,NO,69,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-0.973,-3.476,2.503,,,G,A,0.22,-1.24,4.194,,93.01,PPH,-1.01833,0.111618,0.00127498,0.361889 beta-lactamase_I93P,beta-lactamase_93,TEM-1,beta-lactamase,P62593,0.362087,NO,93,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.401,-2.926,1.525,5.74695,0.128,E,B,0.77,0.44,1.757,,67.83,BHB,-1.873,0.221079,0.00527066,0.362087 kka2_1:1_T130H,kka2_1:1_130,Kka2,kka2_1:1,P00552,0.36219,NO,130,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.392,-3.566,1.174,,0.561,G,A,0.22,0.77,0.5,,92.05,HPO,-1.62633,0.520039,0.00804204,0.36219 kka2_1:8_L92H,kka2_1:8_92,Kka2,kka2_1:8,P00552,0.362203,NO,92,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.893,-4.966,4.073,,0.007,E,B,1.59,-0.19,1.719,,63.26,HHH,-0.962,0.100394,0.00307177,0.362203 kka2_1:8_L92H,kka2_1:8_92,Kka2,kka2_1:8,P00552,0.362203,NO,92,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.893,-4.966,4.073,,0.007,E,B,1.59,-0.19,1.719,,63.26,HHH,-0.962,0.100394,0.00307177,0.362203 kka2_1:1_L152F,kka2_1:1_152,Kka2,kka2_1:1,P00552,0.36222,NO,152,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.521,-4.081,2.56,,0.547,.,A,0.55,1.36,1.589,,63.64,OHH,-1.162,0.520039,0.00674868,0.36222 kka2_1:2_Q219E,kka2_1:2_219,Kka2,kka2_1:2,P00552,0.362242,NO,219,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-0.93,-2.854,1.924,,0.088,H,A,0.4,-0.85,1.917,,50,HPA,-1.05167,0.295029,0.00237913,0.362242 gb1_Q258P,gb1_258,gb1,gb1,P06654,0.362258,NO,258,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.095,-3.626,1.531,,,,,,,0.86,,37.28,BPH,-1.88333,0.177985,0.00437595,0.362258 beta-lactamase_625_G236E,beta-lactamase_625_236,TEM-1,beta-lactamase_625,P62593,0.362313,NO,236,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.784,-3.634,2.85,,0.241,,b,0.29,-0.59,3.506,,64.69,HOO,-1.025,0.213352,0.00162372,0.362313 beta-lactamase_2500_W208S,beta-lactamase_2500_208,TEM-1,beta-lactamase_2500,P62593,0.362385,NO,208,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-0.818,-3.836,3.018,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.361275,0.00126609,0.362385 beta-lactamase_2500_R202F,beta-lactamase_2500_202,TEM-1,beta-lactamase_2500,P62593,0.36239,NO,202,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.292,-4.334,3.042,,0.188,H,A,1.2,0.62,3.734,,77.62,PBP,-1.54767,0.361275,0.00321899,0.36239 kka2_1:1_Q252A,kka2_1:1_252,Kka2,kka2_1:1,P00552,0.362406,NO,252,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.63,-2.051,-0.579,,0.906,H,A,0.64,0.35,1.369,,92.05,PPB,-2.20733,0.520039,0.0121001,0.362406 kka2_1:8_V214W,kka2_1:8_214,Kka2,kka2_1:8,P00552,0.362432,NO,214,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.261,-5.433,4.172,,0.117,E,B,1.48,-0.31,1.859,,64.39,OHH,-0.941667,0.100394,0.00692782,0.362432 kka2_1:8_V214W,kka2_1:8_214,Kka2,kka2_1:8,P00552,0.362432,NO,214,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.261,-5.433,4.172,,0.117,E,B,1.48,-0.31,1.859,,64.39,OHH,-0.941667,0.100394,0.00692782,0.362432 kka2_1:1_N200E,kka2_1:1_200,Kka2,kka2_1:1,P00552,0.362467,NO,200,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-2.446,-2.236,-0.21,,0.756,T,L,0.61,-0.08,17.299,17.299,64.39,APO,-2.08,0.520039,0.00838549,0.362467 kka2_1:1_A224D,kka2_1:1_224,Kka2,kka2_1:1,P00552,0.362491,NO,224,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.977,-3.763,2.786,,,H,A,0.46,-1.26,1.725,,63.64,HHP,-1.41033,0.520039,0.00352047,0.362491 beta-lactamase_39_F64E,beta-lactamase_39_64,TEM-1,beta-lactamase_39,P62593,0.362522,NO,64,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-0.841,-3.89,3.049,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.0495842,0.000947691,0.362522 kka2_1:2_Y257T,kka2_1:2_257,Kka2,kka2_1:2,P00552,0.362539,NO,257,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-1.064,-3.734,2.67,,0.022,H,A,0.21,-0.88,0.833,,52.65,HHB,-1.39333,0.295029,0.0148191,0.362539 kka2_1:8_I196H,kka2_1:8_196,Kka2,kka2_1:8,P00552,0.362547,NO,196,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-2.115,-4.791,2.676,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.100394,0.0107273,0.362547 kka2_1:8_I196H,kka2_1:8_196,Kka2,kka2_1:8,P00552,0.362547,NO,196,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-2.115,-4.791,2.676,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.100394,0.0107273,0.362547 kka2_1:1_R147H,kka2_1:1_147,Kka2,kka2_1:1,P00552,0.362565,NO,147,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.123,-2.32,1.197,,0.094,H,A,1.2,0.97,2.578,,64.02,PBH,-1.98267,0.520039,0.00549168,0.362565 kka2_1:4_F171S,kka2_1:4_171,Kka2,kka2_1:4,P00552,0.362577,NO,171,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.326,-3.759,2.433,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.168804,0.00821426,0.362577 beta-lactamase_625_L79T,beta-lactamase_625_79,TEM-1,beta-lactamase_625,P62593,0.362593,NO,79,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.842,-3.447,2.605,,0.007,H,A,0.55,-0.16,0.935,,50.35,HHP,-1.44333,0.213352,0.000947397,0.362593 kka2_1:4_L70Q,kka2_1:4_70,Kka2,kka2_1:4,P00552,0.362651,NO,70,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.017,-4.149,3.132,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.168804,0.00411884,0.362651 beta-lactamase_2500_L188G,beta-lactamase_2500_188,TEM-1,beta-lactamase_2500,P62593,0.362689,NO,188,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.166,-3.699,2.533,,,H,A,0.55,-0.3,17.865,17.865,60.14,PHB,-1.47033,0.361275,0.00295687,0.362689 kka2_1:2_C209P,kka2_1:2_209,Kka2,kka2_1:2,P00552,0.362734,NO,209,C,P,CP,Special,Special,5.07,6.3,1.23,169,121,115,-6,108.5,112.7,4.2,-0.906,-4.156,3.25,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.295029,0.00260862,0.362734 kka2_1:1_A168G,kka2_1:1_168,Kka2,kka2_1:1,P00552,0.362745,NO,168,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.989,-2.951,0.962,,0.67,H,A,0.46,0.15,25.546,25.546,64.39,OHA,-2.12933,0.520039,0.00806773,0.362745 kka2_1:4_E63K,kka2_1:4_63,Kka2,kka2_1:4,P00552,0.362767,NO,63,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-0.762,-3.035,2.273,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.168804,0.00118399,0.362767 beta-lactamase_2500_K30G,beta-lactamase_2500_30,TEM-1,beta-lactamase_2500,P62593,0.362799,NO,30,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-2.307,-3.406,1.099,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.361275,0.00448593,0.362799 kka2_1:1_E3A,kka2_1:1_3,Kka2,kka2_1:1,P00552,0.362822,NO,3,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.199,-2.95,0.751,,,,,,,3.435,,92.05,HAP,-2.11567,0.520039,0.00267607,0.362822 kka2_1:4_L259Q,kka2_1:4_259,Kka2,kka2_1:4,P00552,0.362859,NO,259,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.088,-4.124,3.036,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.168804,0.0206964,0.362859 beta-lactamase_625_C75W,beta-lactamase_625_75,TEM-1,beta-lactamase_625,P62593,0.362869,NO,75,C,W,CW,Special,Hydrophobic,5.07,5.89,0.82,215,121,204,83,108.5,227.8,119.3,-1.245,-5.246,4.001,,,H,A,0.46,-0.87,2.141,,50,HOO,-1.24333,0.213352,0.0034616,0.362869 kka2_1:8_D183W,kka2_1:8_183,Kka2,kka2_1:8,P00552,0.362876,NO,183,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.204,-5.594,4.39,,0.518,.,b,0.75,0.25,0.347,,52.27,AAH,-1.40533,0.100394,0.00426304,0.362876 kka2_1:8_D183W,kka2_1:8_183,Kka2,kka2_1:8,P00552,0.362876,NO,183,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.204,-5.594,4.39,,0.518,.,b,0.75,0.25,0.347,,52.27,AAH,-1.40533,0.100394,0.00426304,0.362876 kka2_1:4_L212I,kka2_1:4_212,Kka2,kka2_1:4,P00552,0.362883,NO,212,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.904,-3.012,2.108,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.168804,0.0031426,0.362883 Ubiquitin_G75D,Ubiquitin_75,Uba1,Ubiquitin,P0CG48,0.362903,NO,75,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.613,-2.89,1.277,5.44099,0.552,T,A,0.73,0.9,4.017,,34.31,BOO,-1.66767,0.205827,0.000712673,0.362903 Ubiquitin_I61P,Ubiquitin_61,Uba1,Ubiquitin,P0CG48,0.362903,NO,61,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.514,-4.085,2.571,5.19922,0.038,,B,1,-0.76,1.953,,24.53,PHP,-1.70833,0.205827,0.000738268,0.362903 Ubiquitin_K27E,Ubiquitin_27,Uba1,Ubiquitin,P0CG48,0.362903,NO,27,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.064,-3.083,2.019,4.77438,0.086,H,A,2.89,-0.74,2.662,,27.01,HBH,-1.42667,0.205827,0.000767556,0.362903 beta-lactamase_2500_G142D,beta-lactamase_2500_142,TEM-1,beta-lactamase_2500,P62593,0.362904,NO,142,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.707,-3.466,2.759,,0.034,,p,0.29,-0.64,1.883,,64.69,OOO,-0.834,0.361275,0.00060149,0.362904 kka2_1:2_F240S,kka2_1:2_240,Kka2,kka2_1:2,P00552,0.362922,NO,240,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-0.911,-3.673,2.762,,,H,A,0.58,-1.21,0.373,,50.38,BHH,-1.67267,0.295029,0.00552543,0.362922 kka2_1:1_A237N,kka2_1:1_237,Kka2,kka2_1:1,P00552,0.362956,NO,237,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.12,-4.131,2.011,,0.068,H,A,0.46,-0.71,2.369,,92.05,HHA,-2.10433,0.520039,0.012257,0.362956 kka2_1:1_F240T,kka2_1:1_240,Kka2,kka2_1:1,P00552,0.363083,NO,240,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-0.911,-3.673,2.762,,,H,A,1.62,-1.21,5.798,,50.38,BHH,-1.67267,0.520039,0.00552543,0.363083 kka2_1:1_E96L,kka2_1:1_96,Kka2,kka2_1:1,P00552,0.363165,NO,96,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.573,-3.338,0.765,,0.476,,B,1.52,-0.65,1.254,,71.59,OAH,-2.143,0.520039,0.00369441,0.363165 kka2_1:1_D180E,kka2_1:1_180,Kka2,kka2_1:1,P00552,0.363215,NO,180,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.416,-2.535,0.119,,1.03,S,a,0.75,1.5,1.534,,71.59,OAO,-2.02933,0.520039,0.00756412,0.363215 kka2_1:1_L67S,kka2_1:1_67,Kka2,kka2_1:1,P00552,0.363319,NO,67,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.741,-3.639,2.898,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.520039,0.00102787,0.363319 beta-lactamase_S104D,beta-lactamase_104,TEM-1,beta-lactamase,P62593,0.363354,NO,104,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.015,-3.41,2.395,4.92365,0.04,,b,0.82,0.57,4.02,,63.29,HPO,-1.05267,0.221079,0.00218083,0.363354 kka2_1:4_L184N,kka2_1:4_184,Kka2,kka2_1:4,P00552,0.363405,NO,184,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.496,-4.154,2.658,,0.489,E,B,1.59,-0.06,4.495,,63.26,AHH,-1.24833,0.168804,0.00518742,0.363405 kka2_1:1_M197G,kka2_1:1_197,Kka2,kka2_1:1,P00552,0.363414,NO,197,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.707,-3.845,2.138,,0.121,E,B,1.59,-1.19,2.097,,65.53,HHH,-1.847,0.520039,0.00921295,0.363414 kka2_1:8_G30P,kka2_1:8_30,Kka2,kka2_1:8,P00552,0.363462,NO,30,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.596,-3.908,3.312,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.100394,0.00159208,0.363462 kka2_1:8_G30P,kka2_1:8_30,Kka2,kka2_1:8,P00552,0.363462,NO,30,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.596,-3.908,3.312,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.100394,0.00159208,0.363462 kka2_1:4_R38V,kka2_1:4_38,Kka2,kka2_1:4,P00552,0.36347,NO,38,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.207,-2.691,1.484,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.168804,0.00372499,0.36347 beta-lactamase_L218K,beta-lactamase_218,TEM-1,beta-lactamase,P62593,0.363557,NO,218,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.391,-2.186,0.795,4.88972,,I,b,2.89,-0.53,12.788,12.788,74.48,OHH,-1.58867,0.221079,0.00618274,0.363557 kka2_1:4_M116N,kka2_1:4_116,Kka2,kka2_1:4,P00552,0.363639,NO,116,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-2.482,-4.236,1.754,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.168804,0.00745147,0.363639 kka2_1:2_G233I,kka2_1:2_233,Kka2,kka2_1:2,P00552,0.363645,NO,233,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.748,-4.263,3.515,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.295029,0.00232366,0.363645 kka2_1:1_R44T,kka2_1:1_44,Kka2,kka2_1:1,P00552,0.363813,NO,44,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.062,-3.662,1.6,,0.487,S,B,1.2,-0.35,2.717,,71.59,OBO,-1.80767,0.520039,0.00745043,0.363813 beta-lactamase_625_I280W,beta-lactamase_625_280,TEM-1,beta-lactamase_625,P62593,0.363824,NO,280,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.213352,0.0530888,0.363824 beta-lactamase_Y260W,beta-lactamase_260,TEM-1,beta-lactamase,P62593,0.363897,NO,260,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-1.101,-4.372,3.271,5.50878,,E,B,0.73,-1.04,0.865,,60.49,HHP,-1.83433,0.221079,0.00471757,0.363897 kka2_1:2_A79W,kka2_1:2_79,Kka2,kka2_1:2,P00552,0.363979,NO,79,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.368,-5.595,3.227,,0.563,.,B,0.46,-0.43,0.475,,71.59,HHH,-1.752,0.295029,0.00664821,0.363979 kka2_1:4_A117T,kka2_1:4_117,Kka2,kka2_1:4,P00552,0.364008,NO,117,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.828,-3.259,2.431,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.168804,0.00282984,0.364008 kka2_1:1_D90P,kka2_1:1_90,Kka2,kka2_1:1,P00552,0.364022,NO,90,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.459,-4.102,1.643,,0.104,E,B,0.75,0.73,6.085,,64.39,BAH,-1.72833,0.520039,0.00583842,0.364022 kka2_1:8_E96I,kka2_1:8_96,Kka2,kka2_1:8,P00552,0.364032,NO,96,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.573,-3.722,1.149,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.100394,0.00369441,0.364032 kka2_1:8_E96I,kka2_1:8_96,Kka2,kka2_1:8,P00552,0.364032,NO,96,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.573,-3.722,1.149,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.100394,0.00369441,0.364032 beta-lactamase_156_G249Q,beta-lactamase_156_249,TEM-1,beta-lactamase_156,P62593,0.364048,NO,249,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.111618,0.00220169,0.364048 kka2_1:1_L94E,kka2_1:1_94,Kka2,kka2_1:1,P00552,0.364087,NO,94,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.618,-3.883,2.265,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.520039,0.00520888,0.364087 beta-lactamase_W227H,beta-lactamase_227,TEM-1,beta-lactamase,P62593,0.364105,NO,227,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-0.982,-4.704,3.722,4.86393,0.272,,B,0.99,-0.29,1.37,,74.48,OHH,-1.595,0.221079,0.00226019,0.364105 kka2_1:1_S104V,kka2_1:1_104,Kka2,kka2_1:1,P00552,0.364157,NO,104,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.436,-2.726,1.29,,0.536,T,A,0.27,-1.11,5.49,,63.64,HPP,-1.91433,0.520039,0.00555207,0.364157 kka2_1:1_L53F,kka2_1:1_53,Kka2,kka2_1:1,P00552,0.364182,NO,53,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-2.681,-4.426,1.745,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.520039,0.00671168,0.364182 beta-lactamase_156_D177Y,beta-lactamase_156_177,TEM-1,beta-lactamase_156,P62593,0.364191,NO,177,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.967,-4.413,3.446,,0.006,T,L,0.75,-1.02,2.072,,64.69,BAP,-0.873667,0.111618,0.000864022,0.364191 kka2_1:4_L170V,kka2_1:4_170,Kka2,kka2_1:4,P00552,0.364217,NO,170,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.28,-1.716,0.436,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.168804,0.00730791,0.364217 beta-lactamase_625_I244H,beta-lactamase_625_244,TEM-1,beta-lactamase_625,P62593,0.364235,NO,244,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.555,-4.957,3.402,,,E,B,0.48,-0.84,2.061,,77.62,OHH,-1.385,0.213352,0.00605379,0.364235 kka2_1:1_G99F,kka2_1:1_99,Kka2,kka2_1:1,P00552,0.364271,NO,99,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.596,-4.32,3.724,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.520039,0.00186055,0.364271 E1_Ubiquitin_L43K,E1_Ubiquitin_43,Uba1,E1_Ubiquitin,P0CG63,0.364279,NO,43,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.188,-3.492,2.304,,,E,B,,-1.17,,,,BHH,-1.30733,0.18783,0.00190185,0.364279 kka2_1:2_L60H,kka2_1:2_60,Kka2,kka2_1:2,P00552,0.364329,NO,60,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.997,-4.966,3.969,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.295029,0.00262176,0.364329 kka2_1:1_K112I,kka2_1:1_112,Kka2,kka2_1:1,P00552,0.364336,NO,112,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-2.491,-2.233,-0.258,,0.076,H,A,2.34,-1.37,23.433,23.433,56.06,ABH,-2.00133,0.520039,0.00645389,0.364336 kka2_1:2_M148K,kka2_1:2_148,Kka2,kka2_1:2,P00552,0.364336,NO,148,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.847,-3.762,1.915,,0.268,H,A,1.59,0.71,1.439,,64.39,BHA,-1.65467,0.295029,0.00982664,0.364336 kka2_1:1_G189L,kka2_1:1_189,Kka2,kka2_1:1,P00552,0.364342,NO,189,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.596,-3.836,3.24,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.520039,0.00253688,0.364342 beta-lactamase_2500_R257Q,beta-lactamase_2500_257,TEM-1,beta-lactamase_2500,P62593,0.364407,NO,257,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.361275,0.00756629,0.364407 kka2_1:4_H162L,kka2_1:4_162,Kka2,kka2_1:4,P00552,0.364475,NO,162,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-2.319,-3.554,1.235,,0.071,G,A,0.17,1.01,3.187,,64.39,ABP,-2.02067,0.168804,0.00616145,0.364475 kka2_1:2_L223N,kka2_1:2_223,Kka2,kka2_1:2,P00552,0.364548,NO,223,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.861,-4.196,3.335,,,H,A,0.55,-1.24,0.266,,50,HHH,-0.854333,0.295029,0.00253574,0.364548 beta-lactamase_625_R59F,beta-lactamase_625_59,TEM-1,beta-lactamase_625,P62593,0.364549,NO,59,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.345,-4.379,3.034,,0.329,S,L,1.2,-0.09,2.995,,73.08,HBO,-2.24267,0.213352,0.00318082,0.364549 beta-lactamase_R241Y,beta-lactamase_241,TEM-1,beta-lactamase,P62593,0.364594,NO,241,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.433,-4.279,2.846,5.02621,0.094,E,B,0.68,-0.16,1.327,,50,PBO,-1.42967,0.221079,0.00452736,0.364594 kka2_1:8_F203R,kka2_1:8_203,Kka2,kka2_1:8,P00552,0.364601,NO,203,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-0.911,-4.185,3.274,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.100394,0.00318738,0.364601 kka2_1:8_F203R,kka2_1:8_203,Kka2,kka2_1:8,P00552,0.364601,NO,203,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-0.911,-4.185,3.274,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.100394,0.00318738,0.364601 kka2_1:8_A215I,kka2_1:8_215,Kka2,kka2_1:8,P00552,0.364612,NO,215,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.968,-3.723,2.755,,0.039,E,B,1.04,-0.59,2.77,,50.38,HHA,-1.00467,0.100394,0.00529129,0.364612 kka2_1:8_A215I,kka2_1:8_215,Kka2,kka2_1:8,P00552,0.364612,NO,215,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.968,-3.723,2.755,,0.039,E,B,1.04,-0.59,2.77,,50.38,HHA,-1.00467,0.100394,0.00529129,0.364612 beta-lactamase_2500_L146W,beta-lactamase_2500_146,TEM-1,beta-lactamase_2500,P62593,0.364714,NO,146,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.462,-2.894,1.432,,0.007,H,A,0.55,-0.56,1.578,,64.69,AHP,-1.656,0.361275,0.00474542,0.364714 beta-lactamase_W286K,beta-lactamase_286,TEM-1,beta-lactamase,P62593,0.364717,NO,286,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-1.111,-3.724,2.613,6.64456,0.492,,?,0.01,0.6,,,,BHX,-1.478,0.221079,,0.364717 beta-lactamase_156_D155V,beta-lactamase_156_155,TEM-1,beta-lactamase_156,P62593,0.364738,NO,155,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.889,-3.778,2.889,,0.049,,B,0.75,-0.9,0.315,,64.69,OAB,-1.62267,0.111618,0.00135315,0.364738 beta-lactamase_2500_V259S,beta-lactamase_2500_259,TEM-1,beta-lactamase_2500,P62593,0.364744,NO,259,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.361275,0.0070773,0.364744 kka2_1:1_L93A,kka2_1:1_93,Kka2,kka2_1:1,P00552,0.364763,NO,93,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.815,-3.129,2.314,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.520039,0.00131498,0.364763 beta-lactamase_N134L,beta-lactamase_134,TEM-1,beta-lactamase,P62593,0.364802,NO,134,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-0.879,-3.581,2.702,5.07245,0.138,H,A,0.09,-0.6,1.441,,53.15,HPH,-1.02233,0.221079,0.000644786,0.364802 kka2_1:1_E161W,kka2_1:1_161,Kka2,kka2_1:1,P00552,0.364914,NO,161,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.581,-5.534,3.953,,0.829,G,A,1.04,2.24,1.612,,92.05,AAB,-1.861,0.520039,0.00760103,0.364914 beta-lactamase_2500_E169P,beta-lactamase_2500_169,TEM-1,beta-lactamase_2500,P62593,0.365028,NO,169,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.23,-3.768,2.538,,0.337,,A,1.04,1,1.806,,73.08,PAH,-1.16533,0.361275,0.00400994,0.365028 beta-lactamase_156_S104E,beta-lactamase_156_104,TEM-1,beta-lactamase_156,P62593,0.36503,NO,104,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.015,-3.366,2.351,,0.04,,b,0.27,0.57,4.02,,63.29,HPO,-1.05267,0.111618,0.00218083,0.36503 kka2_1:1_L47H,kka2_1:1_47,Kka2,kka2_1:1,P00552,0.365033,NO,47,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.265,-4.833,3.568,,0.139,E,B,0.55,-0.86,14.593,14.593,63.26,HHH,-1.77933,0.520039,0.00509386,0.365033 kka2_1:1_W24V,kka2_1:1_24,Kka2,kka2_1:1,P00552,0.365056,NO,24,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-1.779,-2.484,0.705,,0.477,E,B,0.47,-0.21,2.375,,56.06,AHH,-2.24467,0.520039,0.00631564,0.365056 kka2_1:8_A25P,kka2_1:8_25,Kka2,kka2_1:8,P00552,0.365056,NO,25,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.496,-3.994,1.498,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.100394,0.00595636,0.365056 kka2_1:8_A25P,kka2_1:8_25,Kka2,kka2_1:8,P00552,0.365056,NO,25,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.496,-3.994,1.498,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.100394,0.00595636,0.365056 kka2_1:2_F264V,kka2_1:2_264,Kka2,kka2_1:2,P00552,0.365092,NO,264,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.02,-3.361,2.341,,0.296,.,?,0.58,0.02,2.303,,71.59,HHNA,-0.9655,0.295029,,0.365092 kka2_1:1_L70A,kka2_1:1_70,Kka2,kka2_1:1,P00552,0.365102,NO,70,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.017,-3.191,2.174,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.520039,0.00411884,0.365102 kka2_1:4_L158G,kka2_1:4_158,Kka2,kka2_1:4,P00552,0.365104,NO,158,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.947,-3.704,1.757,,0.095,,B,1.59,0.77,7.588,,63.64,AHA,-1.25333,0.168804,0.00529068,0.365104 kka2_1:1_W91N,kka2_1:1_91,Kka2,kka2_1:1,P00552,0.365111,NO,91,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-1.178,-4.186,3.008,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.520039,0.00358653,0.365111 beta-lactamase_625_S68N,beta-lactamase_625_68,TEM-1,beta-lactamase_625,P62593,0.365114,NO,68,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-0.913,-2.44,1.527,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.213352,0.000800065,0.365114 kka2_1:1_L243C,kka2_1:1_243,Kka2,kka2_1:1,P00552,0.365116,NO,243,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-2.651,-2.68,0.029,,0.277,H,A,0.55,-0.67,4.334,,92.05,HHH,-2.03767,0.520039,0.00884927,0.365116 kka2_1:2_Y257H,kka2_1:2_257,Kka2,kka2_1:2,P00552,0.365134,NO,257,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-1.064,-4.042,2.978,,0.022,H,A,0.21,-0.88,0.833,,52.65,HHB,-1.39333,0.295029,0.0148191,0.365134 beta-lactamase_625_R59E,beta-lactamase_625_59,TEM-1,beta-lactamase_625,P62593,0.365205,NO,59,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.345,-3.322,1.977,,0.329,S,L,1.2,-0.09,2.995,,73.08,HBO,-2.24267,0.213352,0.00318082,0.365205 WW_domain_N191R,WW_domain_191,Yap65,WW_domain,P46937,0.365209,NO,191,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-1.519,-3.34,1.821,5.96016,,,,,,5.117,,66.07,HPB,-1.554,0.153962,0.00270999,0.365209 kka2_1:2_R211M,kka2_1:2_211,Kka2,kka2_1:2,P00552,0.365264,NO,211,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-0.899,-4.531,3.632,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.295029,0.00204888,0.365264 beta-lactamase_2500_V259Y,beta-lactamase_2500_259,TEM-1,beta-lactamase_2500,P62593,0.365315,NO,259,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.361275,0.0070773,0.365315 kka2_1:1_Q136V,kka2_1:1_136,Kka2,kka2_1:1,P00552,0.365333,NO,136,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-3.021,-3.774,0.753,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.520039,0.00624149,0.365333 beta-lactamase_625_R257E,beta-lactamase_625_257,TEM-1,beta-lactamase_625,P62593,0.365378,NO,257,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.213352,0.00756629,0.365378 beta-lactamase_625_L73D,beta-lactamase_625_73,TEM-1,beta-lactamase_625,P62593,0.365455,NO,73,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.507,-4.091,2.584,,,H,A,0.55,-0.64,2.933,,67.83,HHH,-1.487,0.213352,0.00488983,0.365455 beta-lactamase_2500_G142E,beta-lactamase_2500_142,TEM-1,beta-lactamase_2500,P62593,0.36552,NO,142,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.707,-3.628,2.921,,0.034,,p,0.29,-0.64,1.883,,64.69,OOO,-0.834,0.361275,0.00060149,0.36552 kka2_1:1_L243Y,kka2_1:1_243,Kka2,kka2_1:1,P00552,0.365549,NO,243,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-2.651,-4.342,1.691,,0.277,H,A,0.55,-0.67,4.334,,92.05,HHH,-2.03767,0.520039,0.00884927,0.365549 beta-lactamase_156_G43T,beta-lactamase_156_43,TEM-1,beta-lactamase_156,P62593,0.365562,NO,43,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.62,-3.646,3.026,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.111618,0.00120151,0.365562 kka2_1:4_G233R,kka2_1:4_233,Kka2,kka2_1:4,P00552,0.365607,NO,233,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.748,-4.006,3.258,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.168804,0.00232366,0.365607 kka2_1:2_L92R,kka2_1:2_92,Kka2,kka2_1:2,P00552,0.365638,NO,92,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.893,-4.021,3.128,,0.007,E,B,1.59,-0.19,1.447,,63.26,HHH,-0.962,0.295029,0.00307177,0.365638 beta-lactamase_625_R220Y,beta-lactamase_625_220,TEM-1,beta-lactamase_625,P62593,0.365648,NO,220,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-0.942,-4.188,3.246,,0.295,I,A,1.2,-0.76,5.086,,74.48,HBP,-1.33633,0.213352,0.00232421,0.365648 beta-lactamase_L282K,beta-lactamase_282,TEM-1,beta-lactamase,P62593,0.365653,NO,282,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.586,-3.805,2.219,5.16743,0.007,H,A,1.07,0.34,31.31,31.31,63.99,PHH,-1.82367,0.221079,0.0449821,0.365653 beta-lactamase_156_V260D,beta-lactamase_156_260,TEM-1,beta-lactamase_156,P62593,0.365664,NO,260,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.111618,0.00471757,0.365664 kka2_1:1_R239D,kka2_1:1_239,Kka2,kka2_1:1,P00552,0.365695,NO,239,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.949,-2.803,-0.146,,0.15,H,A,1.2,-0.31,0.477,,71.59,ABH,-2.23,0.520039,0.00835326,0.365695 kka2_1:1_D220F,kka2_1:1_220,Kka2,kka2_1:1,P00552,0.365706,NO,220,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.787,-4.288,3.501,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.520039,0.00158066,0.365706 kka2_1:1_F48W,kka2_1:1_48,Kka2,kka2_1:1,P00552,0.365724,NO,48,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.453,-4.763,3.31,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.520039,0.00475422,0.365724 beta-lactamase_625_T126P,beta-lactamase_625_126,TEM-1,beta-lactamase_625,P62593,0.365807,NO,126,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.122,-3.758,2.636,,0.05,H,A,0.22,-0.05,0.817,,44.41,HPH,-1.60467,0.213352,0.00244552,0.365807 kka2_1:4_L212R,kka2_1:4_212,Kka2,kka2_1:4,P00552,0.365932,NO,212,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.904,-4.001,3.097,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.168804,0.0031426,0.365932 kka2_1:2_L158D,kka2_1:2_158,Kka2,kka2_1:2,P00552,0.366053,NO,158,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.947,-4.014,2.067,,0.095,,B,1.59,0.77,7.588,,63.64,AHA,-1.25333,0.295029,0.00529068,0.366053 beta-lactamase_625_L248N,beta-lactamase_625_248,TEM-1,beta-lactamase_625,P62593,0.366054,NO,248,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.213352,0.00428493,0.366054 kka2_1:4_L94E,kka2_1:4_94,Kka2,kka2_1:4,P00552,0.366088,NO,94,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.618,-3.883,2.265,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.168804,0.00520888,0.366088 kka2_1:1_V49I,kka2_1:1_49,Kka2,kka2_1:1,P00552,0.366092,NO,49,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.614,-2.255,0.641,,,E,B,0.44,-0.77,3.665,3.665,64.39,HHB,-1.3,0.520039,0.00615685,0.366092 kka2_1:1_E142R,kka2_1:1_142,Kka2,kka2_1:1,P00552,0.366108,NO,142,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.221,-2.483,0.262,,0.471,H,A,1.52,0.85,3.626,,65.53,HAB,-2.08033,0.520039,0.00748883,0.366108 WW_domain_A180I,WW_domain_180,Yap65,WW_domain,P46937,0.366127,NO,180,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.242,-3.4,2.158,6.02829,,,,,,0.627,,23.61,HHB,-1.37767,0.153962,0.00413929,0.366127 kka2_1:8_L212N,kka2_1:8_212,Kka2,kka2_1:8,P00552,0.366187,NO,212,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.904,-4.173,3.269,,,,B,1.59,-0.78,1.708,,42.42,BHO,-0.799667,0.100394,0.0031426,0.366187 kka2_1:8_L212N,kka2_1:8_212,Kka2,kka2_1:8,P00552,0.366187,NO,212,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.904,-4.173,3.269,,,,B,1.59,-0.78,1.708,,42.42,BHO,-0.799667,0.100394,0.0031426,0.366187 beta-lactamase_L160Y,beta-lactamase_160,TEM-1,beta-lactamase,P62593,0.366265,NO,160,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.977,-3.98,3.003,5.32068,0.022,,B,1.75,-0.6,0.895,,44.41,BHA,-0.936,0.221079,0.00193775,0.366265 beta-lactamase_2500_L167F,beta-lactamase_2500_167,TEM-1,beta-lactamase_2500,P62593,0.366316,NO,167,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.138,-3.813,2.675,,0.015,G,A,0.55,-0.63,7.813,,64.69,AHP,-1.30767,0.361275,0.00303566,0.366316 beta-lactamase_2500_L219Q,beta-lactamase_2500_219,TEM-1,beta-lactamase_2500,P62593,0.366323,NO,219,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.313,-4.292,2.979,,,I,A,0.55,-0.51,35.994,35.994,74.48,HHB,-1.21533,0.361275,0.00664345,0.366323 beta-lactamase_2500_S104Y,beta-lactamase_2500_104,TEM-1,beta-lactamase_2500,P62593,0.36637,NO,104,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.015,-4.223,3.208,,0.04,,b,0.27,0.57,1.133,,63.29,HPO,-1.05267,0.361275,0.00218083,0.36637 kka2_1:2_L67W,kka2_1:2_67,Kka2,kka2_1:2,P00552,0.366376,NO,67,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.741,-5.126,4.385,,0.007,H,A,1.59,-0.66,,,,BHP,-1.42867,0.295029,0.00102787,0.366376 beta-lactamase_L79E,beta-lactamase_79,TEM-1,beta-lactamase,P62593,0.366388,NO,79,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.842,-3.887,3.045,4.98681,0.007,H,A,1.07,-0.16,0.823,,50.35,HHP,-1.44333,0.221079,0.000947397,0.366388 kka2_1:1_G10D,kka2_1:1_10,Kka2,kka2_1:1,P00552,0.366388,NO,10,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.921,-2.473,0.552,,,,,,,1.862,,71.59,HOP,-2.10733,0.520039,0.00289233,0.366388 kka2_1:1_D261M,kka2_1:1_261,Kka2,kka2_1:1,P00552,0.366398,NO,261,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.708,-4.958,4.25,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.520039,0.0224846,0.366398 kka2_1:4_F264G,kka2_1:4_264,Kka2,kka2_1:4,P00552,0.366427,NO,264,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.02,-3.702,2.682,,0.296,,?,1.62,0.02,1.93,,71.59,HHO,-0.9655,0.168804,,0.366427 beta-lactamase_2500_C121S,beta-lactamase_2500_121,TEM-1,beta-lactamase_2500,P62593,0.366439,NO,121,C,S,CS,Special,Polar,5.07,5.68,0.61,112,121,105,-16,108.5,89,-19.5,-0.953,-3.411,2.458,,,H,A,0.46,-0.81,1.174,,63.29,HOP,-1.46767,0.361275,0.000744322,0.366439 Pab1_A199P,Pab1_199,Pab1,Pab1,P04147,0.366505,NO,199,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.53,-3.662,2.132,,,,,,,1.479,,80.42,HHO,-1.50467,0.175299,0.00145024,0.366505 kka2_1:8_R217E,kka2_1:8_217,Kka2,kka2_1:8,P00552,0.366511,NO,217,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.158,-3.44,2.282,,0.252,T,A,0.16,-0.59,1.151,,52.27,ABH,-1.127,0.100394,0.0047191,0.366511 kka2_1:8_R217E,kka2_1:8_217,Kka2,kka2_1:8,P00552,0.366511,NO,217,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.158,-3.44,2.282,,0.252,T,A,0.16,-0.59,1.151,,52.27,ABH,-1.127,0.100394,0.0047191,0.366511 beta-lactamase_156_D129E,beta-lactamase_156_129,TEM-1,beta-lactamase_156,P62593,0.366514,NO,129,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.816,-2.232,1.416,,,,B,0.75,-0.69,1.924,,34.97,PAP,-0.818,0.111618,0.00109178,0.366514 kka2_1:2_G233R,kka2_1:2_233,Kka2,kka2_1:2,P00552,0.366566,NO,233,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.748,-4.006,3.258,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.295029,0.00232366,0.366566 beta-lactamase_F58D,beta-lactamase_58,TEM-1,beta-lactamase,P62593,0.366611,NO,58,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-2.914,-3.846,0.932,5.55634,0.266,E,B,1.33,-0.07,2.467,,77.62,PHB,-2.059,0.221079,0.00523369,0.366611 beta-lactamase_L74G,beta-lactamase_74,TEM-1,beta-lactamase,P62593,0.366611,NO,74,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.296,-3.477,2.181,5.50288,,H,A,1.75,-0.91,1.581,,50,HHO,-1.34933,0.221079,0.00493255,0.366611 beta-lactamase_39_L74K,beta-lactamase_39_74,TEM-1,beta-lactamase_39,P62593,0.366633,NO,74,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.296,-3.688,2.392,,,H,A,0.55,-0.91,1.581,,50,HHO,-1.34933,0.0495842,0.00493255,0.366633 kka2_1:1_L174Q,kka2_1:1_174,Kka2,kka2_1:1,P00552,0.366663,NO,174,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.952,-4.163,3.211,,,H,A,0.55,-0.31,13.276,13.276,51.89,BHB,-2.08533,0.520039,0.00438501,0.366663 beta-lactamase_156_D155I,beta-lactamase_156_155,TEM-1,beta-lactamase_156,P62593,0.366709,NO,155,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.889,-4.06,3.171,,0.049,,B,0.75,-0.9,0.315,,64.69,OAB,-1.62267,0.111618,0.00135315,0.366709 kka2_1:1_R211P,kka2_1:1_211,Kka2,kka2_1:1,P00552,0.366897,NO,211,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-0.899,-3.968,3.069,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.520039,0.00204888,0.366897 kka2_1:1_H139L,kka2_1:1_139,Kka2,kka2_1:1,P00552,0.366922,NO,139,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-2.809,-2.514,-0.295,,0.471,H,A,0.17,0.68,1.153,,63.64,BBB,-2.22,0.520039,0.00734779,0.366922 kka2_1:2_G245M,kka2_1:2_245,Kka2,kka2_1:2,P00552,0.366953,NO,245,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.812,-4.937,4.125,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.295029,0.00683899,0.366953 beta-lactamase_156_A133F,beta-lactamase_156_133,TEM-1,beta-lactamase_156,P62593,0.366967,NO,133,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.186,-4.224,3.038,,,H,A,0.46,-0.86,0.805,,67.83,HHP,-0.988333,0.111618,0.00468022,0.366967 kka2_1:1_L259S,kka2_1:1_259,Kka2,kka2_1:1,P00552,0.366997,NO,259,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.088,-3.523,2.435,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.520039,0.0206964,0.366997 kka2_1:1_A166P,kka2_1:1_166,Kka2,kka2_1:1,P00552,0.367108,NO,166,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.407,-2.34,-0.067,,0.534,.,B,0.46,1.03,1.147,,71.59,HHO,-2.421,0.520039,0.00799912,0.367108 beta-lactamase_156_T158L,beta-lactamase_156_158,TEM-1,beta-lactamase_156,P62593,0.367122,NO,158,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.116,-3.303,2.187,,0.036,,B,0.22,-0.85,3.771,,69.58,HPB,-1.269,0.111618,0.00341825,0.367122 beta-lactamase_2500_A170K,beta-lactamase_2500_170,TEM-1,beta-lactamase_2500,P62593,0.367188,NO,170,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.237,-3.643,2.406,,0.126,,L,0.46,-0.35,2.427,,64.69,AHH,-1.63267,0.361275,0.00431903,0.367188 kka2_1:2_A108W,kka2_1:2_108,Kka2,kka2_1:2,P00552,0.36719,NO,108,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.061,-5.601,3.54,,0.243,.,B,0.46,-1.34,2.462,,71.59,HHO,-1.57033,0.295029,0.00751209,0.36719 kka2_1:4_S32L,kka2_1:4_32,Kka2,kka2_1:4,P00552,0.36719,NO,32,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-0.804,-3.386,2.582,,0.768,S,b,0.27,3.75,,,,OPA,-1.74533,0.168804,0.00149998,0.36719 kka2_1:2_L158G,kka2_1:2_158,Kka2,kka2_1:2,P00552,0.367223,NO,158,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.947,-3.704,1.757,,0.095,,B,1.59,0.77,7.588,,63.64,AHA,-1.25333,0.295029,0.00529068,0.367223 beta-lactamase_625_R220F,beta-lactamase_625_220,TEM-1,beta-lactamase_625,P62593,0.367383,NO,220,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-0.942,-4.29,3.348,,0.295,I,A,1.2,-0.76,5.086,,74.48,HBP,-1.33633,0.213352,0.00232421,0.367383 kka2_1:1_A119V,kka2_1:1_119,Kka2,kka2_1:1,P00552,0.36747,NO,119,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.073,-2.406,1.333,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.520039,0.00441074,0.36747 beta-lactamase_T126P,beta-lactamase_126,TEM-1,beta-lactamase,P62593,0.367542,NO,126,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.122,-3.758,2.636,4.82694,0.05,H,A,0.3,-0.05,1.14,,44.41,HPH,-1.60467,0.221079,0.00244552,0.367542 kka2_1:1_R44M,kka2_1:1_44,Kka2,kka2_1:1,P00552,0.367545,NO,44,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.062,-4.711,2.649,,0.487,S,B,1.2,-0.35,2.717,,71.59,OBO,-1.80767,0.520039,0.00745043,0.367545 kka2_1:4_F133I,kka2_1:4_133,Kka2,kka2_1:4,P00552,0.36762,NO,133,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-0.871,-3.407,2.536,,0.178,.,B,0.58,0.43,0.786,,42.42,OHA,-0.871667,0.168804,0.00182168,0.36762 kka2_1:4_F133L,kka2_1:4_133,Kka2,kka2_1:4,P00552,0.367697,NO,133,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-0.871,-2.98,2.109,,0.178,.,B,0.58,0.43,0.786,,42.42,OHA,-0.871667,0.168804,0.00182168,0.367697 kka2_1:1_S32N,kka2_1:1_32,Kka2,kka2_1:1,P00552,0.36772,NO,32,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-0.804,-3.251,2.447,,0.768,S,b,0.27,3.75,,,,OPA,-1.74533,0.520039,0.00149998,0.36772 kka2_1:1_L57T,kka2_1:1_57,Kka2,kka2_1:1,P00552,0.367784,NO,57,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.898,-3.729,1.831,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.520039,0.00723769,0.367784 kka2_1:1_R145G,kka2_1:1_145,Kka2,kka2_1:1,P00552,0.367927,NO,145,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.804,-2.912,1.108,,0.346,H,A,1.2,1.23,23.699,23.699,63.64,HBP,-1.88033,0.520039,0.00846663,0.367927 kka2_1:2_R211H,kka2_1:2_211,Kka2,kka2_1:2,P00552,0.36796,NO,211,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-0.899,-4.319,3.42,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.295029,0.00204888,0.36796 kka2_1:8_L193K,kka2_1:8_193,Kka2,kka2_1:8,P00552,0.367998,NO,193,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.983,-3.668,2.685,,,G,A,1.59,-1.03,2.234,,65.53,OHO,-0.965333,0.100394,0.00480179,0.367998 kka2_1:8_L193K,kka2_1:8_193,Kka2,kka2_1:8,P00552,0.367998,NO,193,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.983,-3.668,2.685,,,G,A,1.59,-1.03,2.234,,65.53,OHO,-0.965333,0.100394,0.00480179,0.367998 kka2_1:1_I246E,kka2_1:1_246,Kka2,kka2_1:1,P00552,0.368057,NO,246,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-2.008,-3.889,1.881,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.520039,0.0139479,0.368057 kka2_1:1_F133I,kka2_1:1_133,Kka2,kka2_1:1,P00552,0.368081,NO,133,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-0.871,-3.407,2.536,,0.178,.,B,0.58,0.43,1.999,,42.42,OHA,-0.871667,0.520039,0.00182168,0.368081 beta-lactamase_2500_D231P,beta-lactamase_2500_231,TEM-1,beta-lactamase_2500,P62593,0.368191,NO,231,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.816,-3.68,2.864,,,E,B,0.75,-1.06,0.319,,65.38,HAB,-0.994,0.361275,0.00107395,0.368191 kka2_1:1_C131L,kka2_1:1_131,Kka2,kka2_1:1,P00552,0.36823,NO,131,C,L,CL,Special,Hydrophobic,5.07,9.7088,4.6388,198,121,131,10,108.5,166.7,58.2,-0.831,-3.161,2.33,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.520039,0.00170814,0.36823 beta-lactamase_2500_G114L,beta-lactamase_2500_114,TEM-1,beta-lactamase_2500,P62593,0.368281,NO,114,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.094,-3.637,2.543,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.361275,0.00224919,0.368281 kka2_1:2_E63K,kka2_1:2_63,Kka2,kka2_1:2,P00552,0.368423,NO,63,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-0.762,-3.035,2.273,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.295029,0.00118399,0.368423 kka2_1:2_R38V,kka2_1:2_38,Kka2,kka2_1:2,P00552,0.368549,NO,38,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.207,-2.691,1.484,,0.355,E,B,1.2,-1.13,6.872,6.872,52.27,HBH,-1.28567,0.295029,0.00372499,0.368549 kka2_1:8_I228F,kka2_1:8_228,Kka2,kka2_1:8,P00552,0.36856,NO,228,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.142,-3.751,2.609,,,H,A,1.52,-1.2,1.521,,71.59,AHH,-1.54633,0.100394,0.00458834,0.36856 kka2_1:8_I228F,kka2_1:8_228,Kka2,kka2_1:8,P00552,0.36856,NO,228,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.142,-3.751,2.609,,,H,A,1.52,-1.2,1.521,,71.59,AHH,-1.54633,0.100394,0.00458834,0.36856 beta-lactamase_156_D155T,beta-lactamase_156_155,TEM-1,beta-lactamase_156,P62593,0.368562,NO,155,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.889,-3.445,2.556,,0.049,,B,0.75,-0.9,0.315,,64.69,OAB,-1.62267,0.111618,0.00135315,0.368562 kka2_1:1_L212C,kka2_1:1_212,Kka2,kka2_1:1,P00552,0.368636,NO,212,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.904,-4.688,3.784,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.520039,0.0031426,0.368636 kka2_1:2_L94D,kka2_1:2_94,Kka2,kka2_1:2,P00552,0.368675,NO,94,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.618,-4.088,2.47,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.295029,0.00520888,0.368675 kka2_1:1_S104Y,kka2_1:1_104,Kka2,kka2_1:1,P00552,0.368703,NO,104,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.436,-4.278,2.842,,0.536,T,A,0.27,-1.11,5.49,,63.64,HPP,-1.91433,0.520039,0.00555207,0.368703 kka2_1:4_G210R,kka2_1:4_210,Kka2,kka2_1:4,P00552,0.368761,NO,210,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.095,-4.007,2.912,,0.103,T,A,0.29,-0.62,0.271,,50,OOB,-0.966667,0.168804,0.00598378,0.368761 kka2_1:1_L223C,kka2_1:1_223,Kka2,kka2_1:1,P00552,0.368799,NO,223,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.861,-4.71,3.849,,,H,A,0.55,-1.24,1.268,,50,HHH,-0.854333,0.520039,0.00253574,0.368799 kka2_1:4_A224Y,kka2_1:4_224,Kka2,kka2_1:4,P00552,0.368896,NO,224,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.977,-4.257,3.28,,,H,A,0.46,-1.26,0.93,,63.64,HHP,-1.41033,0.168804,0.00352047,0.368896 beta-lactamase_2500_L38C,beta-lactamase_2500_38,TEM-1,beta-lactamase_2500,P62593,0.3689,NO,38,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.343,-4.841,3.498,,0.088,H,A,0.55,0.2,2.71,,64.34,PHO,-1.78033,0.361275,0.00373244,0.3689 beta-lactamase_C18K,beta-lactamase_18,TEM-1,beta-lactamase,P62593,0.368938,NO,18,C,K,CK,Special,PositiveCharge,5.07,9.74,4.67,202,121,146,25,108.5,168.6,60.1,-2.26,-3.596,1.336,,,,,,,3.995,,93.01,HOH,-2.093,0.221079,0.002536,0.368938 kka2_1:2_A224G,kka2_1:2_224,Kka2,kka2_1:2,P00552,0.368957,NO,224,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.977,-3.154,2.177,,,H,A,0.46,-1.26,1.646,,63.64,HHP,-1.41033,0.295029,0.00352047,0.368957 kka2_1:1_A191G,kka2_1:1_191,Kka2,kka2_1:1,P00552,0.368987,NO,191,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.831,-3.024,2.193,,,.,b,0.46,-0.94,0.53,,50,AHO,-0.868667,0.520039,0.00338807,0.368987 kka2_1:1_L103V,kka2_1:1_103,Kka2,kka2_1:1,P00552,0.368996,NO,103,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-2.362,-2.108,-0.254,,0.394,T,A,0.55,-0.99,4.121,,63.64,HHP,-1.534,0.520039,0.00574792,0.368996 kka2_1:4_I228M,kka2_1:4_228,Kka2,kka2_1:4,P00552,0.369008,NO,228,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.142,-4.08,2.938,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.168804,0.00458834,0.369008 beta-lactamase_625_S128G,beta-lactamase_625_128,TEM-1,beta-lactamase_625,P62593,0.369052,NO,128,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-0.84,-2.908,2.068,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.213352,0.00071483,0.369052 kka2_1:2_D261M,kka2_1:2_261,Kka2,kka2_1:2,P00552,0.369154,NO,261,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.708,-4.958,4.25,,0.146,G,A,0.75,-0.33,,,,HAA,-0.759333,0.295029,0.0224846,0.369154 kka2_1:1_V36D,kka2_1:1_36,Kka2,kka2_1:1,P00552,0.36929,NO,36,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-0.898,-3.992,3.094,,0.292,E,B,0.44,0.21,0.278,,52.27,HHH,-1.484,0.520039,0.00245633,0.36929 kka2_1:4_W236S,kka2_1:4_236,Kka2,kka2_1:4,P00552,0.369306,NO,236,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-1.363,-3.736,2.373,,0.303,H,A,0.47,-0.76,2.277,,48.48,AHH,-1.81267,0.168804,0.0088796,0.369306 beta-lactamase_625_T178G,beta-lactamase_625_178,TEM-1,beta-lactamase_625,P62593,0.369412,NO,178,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-0.791,-3.358,2.567,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.213352,0.000684366,0.369412 kka2_1:1_R147V,kka2_1:1_147,Kka2,kka2_1:1,P00552,0.369432,NO,147,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.123,-3.865,2.742,,0.094,H,A,1.2,0.97,2.578,,64.02,PBH,-1.98267,0.520039,0.00549168,0.369432 beta-lactamase_2500_G142W,beta-lactamase_2500_142,TEM-1,beta-lactamase_2500,P62593,0.369441,NO,142,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.707,-5.146,4.439,,0.034,,p,0.29,-0.64,1.883,,64.69,OOO,-0.834,0.361275,0.00060149,0.369441 kka2_1:8_D208H,kka2_1:8_208,Kka2,kka2_1:8,P00552,0.369459,NO,208,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.708,-4.483,3.775,,0.36,,l,0.29,-1.01,,,,HAO,-0.929667,0.100394,0.00212588,0.369459 kka2_1:8_D208H,kka2_1:8_208,Kka2,kka2_1:8,P00552,0.369459,NO,208,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.708,-4.483,3.775,,0.36,,l,0.29,-1.01,,,,HAO,-0.929667,0.100394,0.00212588,0.369459 beta-lactamase_2500_L218Q,beta-lactamase_2500_218,TEM-1,beta-lactamase_2500,P62593,0.369522,NO,218,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.391,-3.953,2.562,,,I,b,0.55,-0.53,9.151,9.151,74.48,OHH,-1.58867,0.361275,0.00618274,0.369522 kka2_1:1_A9M,kka2_1:1_9,Kka2,kka2_1:1,P00552,0.369544,NO,9,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.079,-2.864,0.785,,,,,,,0.383,,71.59,BHO,-2.253,0.520039,0.00273264,0.369544 Pab1_S155K,Pab1_155,Pab1,Pab1,P04147,0.369595,NO,155,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.039,-3.574,1.535,,,,,,,,,,PPB,-1.42267,0.175299,0.00208179,0.369595 kka2_1:2_F263S,kka2_1:2_263,Kka2,kka2_1:2,P00552,0.369718,NO,263,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-0.911,-3.673,2.762,,0.006,G,A,1.62,-0.12,5.275,,45.83,AHH,-0.92,0.295029,0.0172454,0.369718 kka2_1:1_F256Q,kka2_1:1_256,Kka2,kka2_1:1,P00552,0.36973,NO,256,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.49,-4.227,2.737,,,H,A,1.62,-0.78,2.354,,53.03,HHH,-1.423,0.520039,0.0132841,0.36973 beta-lactamase_H285P,beta-lactamase_285,TEM-1,beta-lactamase,P62593,0.369734,NO,285,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-1.845,-3.888,2.043,5.64289,0.312,T,a,0.35,0.64,1.401,,72.73,BBH,-1.64567,0.221079,0.101555,0.369734 beta-lactamase_625_I125N,beta-lactamase_625_125,TEM-1,beta-lactamase_625,P62593,0.369813,NO,125,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.441,-4.089,2.648,,,H,A,0.48,-0.7,2.034,,63.29,HHP,-1.248,0.213352,0.00383964,0.369813 beta-lactamase_2500_S241Y,beta-lactamase_2500_241,TEM-1,beta-lactamase_2500,P62593,0.369918,NO,241,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.361275,0.00452736,0.369918 beta-lactamase_2500_E119C,beta-lactamase_2500_119,TEM-1,beta-lactamase_2500,P62593,0.36996,NO,119,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.412,-5.165,3.753,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.361275,0.00386966,0.36996 Pab1_I196R,Pab1_196,Pab1,Pab1,P04147,0.36997,NO,196,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.795,-4.051,2.256,,,,,,,2.013,,80.59,AHH,-1.44667,0.175299,0.0016933,0.36997 kka2_1:1_L57N,kka2_1:1_57,Kka2,kka2_1:1,P00552,0.370111,NO,57,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.898,-4.124,2.226,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.520039,0.00723769,0.370111 kka2_1:1_C77R,kka2_1:1_77,Kka2,kka2_1:1,P00552,0.370144,NO,77,C,R,CR,Special,PositiveCharge,5.07,6.34148,1.27148,180,121,174,53,108.5,173.4,64.9,-1.477,-4.125,2.648,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.520039,0.00441216,0.370144 kka2_1:1_T125L,kka2_1:1_125,Kka2,kka2_1:1,P00552,0.370146,NO,125,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.622,-3.575,0.953,,0.791,T,A,0.22,0.33,1.972,,92.05,BPH,-1.56933,0.520039,0.00821755,0.370146 kka2_1:1_W15Y,kka2_1:1_15,Kka2,kka2_1:1,P00552,0.370166,NO,15,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-1.392,-3.559,2.167,,0.01,G,A,0.47,0.15,20.149,20.149,52.27,HHH,-2.10533,0.520039,0.00585505,0.370166 kka2_1:1_E161K,kka2_1:1_161,Kka2,kka2_1:1,P00552,0.370198,NO,161,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.581,-3.478,1.897,,0.829,G,A,1.04,2.24,1.612,,92.05,AAB,-1.861,0.520039,0.00760103,0.370198 kka2_1:4_D216T,kka2_1:4_216,Kka2,kka2_1:4,P00552,0.370256,NO,216,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.785,-3.493,2.708,,0.018,E,B,0.75,-0.51,0.112,,19.32,HAB,-0.970333,0.168804,0.00229969,0.370256 kka2_1:1_D23A,kka2_1:1_23,Kka2,kka2_1:1,P00552,0.370305,NO,23,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.459,-2.468,0.009,,0.695,E,B,0.75,-0.65,2.655,,65.53,HAH,-1.94033,0.520039,0.007195,0.370305 beta-lactamase_625_L135G,beta-lactamase_625_135,TEM-1,beta-lactamase_625,P62593,0.370317,NO,135,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.002,-3.837,2.835,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.213352,0.00244423,0.370317 kka2_1:4_L184A,kka2_1:4_184,Kka2,kka2_1:4,P00552,0.370354,NO,184,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.496,-2.814,1.318,,0.489,E,B,1.59,-0.06,4.495,,63.26,AHH,-1.24833,0.168804,0.00518742,0.370354 kka2_1:8_G213S,kka2_1:8_213,Kka2,kka2_1:8,P00552,0.370354,NO,213,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.596,-3.189,2.593,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.100394,0.00187654,0.370354 kka2_1:8_G213S,kka2_1:8_213,Kka2,kka2_1:8,P00552,0.370354,NO,213,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.596,-3.189,2.593,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.100394,0.00187654,0.370354 kka2_1:4_V186R,kka2_1:4_186,Kka2,kka2_1:4,P00552,0.370368,NO,186,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.011,-4.25,3.239,,,E,B,0.44,-0.61,0.679,,45.83,HHP,-1.10967,0.168804,0.00409703,0.370368 beta-lactamase_156_A77P,beta-lactamase_156_77,TEM-1,beta-lactamase_156,P62593,0.370437,NO,77,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.234,-3.879,2.645,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.111618,0.00282362,0.370437 kka2_1:4_L193S,kka2_1:4_193,Kka2,kka2_1:4,P00552,0.370448,NO,193,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.983,-3.624,2.641,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.168804,0.00480179,0.370448 beta-lactamase_625_L218Q,beta-lactamase_625_218,TEM-1,beta-lactamase_625,P62593,0.370452,NO,218,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.391,-3.953,2.562,,,I,b,0.55,-0.53,17.202,17.202,74.48,OHH,-1.58867,0.213352,0.00618274,0.370452 beta-lactamase_2500_G281Y,beta-lactamase_2500_281,TEM-1,beta-lactamase_2500,P62593,0.37051,NO,281,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.361275,0.0406482,0.37051 gb1_T277P,gb1_277,gb1,gb1,P06654,0.370512,NO,277,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.771,-3.634,1.863,,,,,,,0.824,,35.71,BPH,-1.54833,0.177985,0.00348258,0.370512 gb1_Y259D,gb1_259,gb1,gb1,P06654,0.370512,NO,259,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-1.78,-3.836,2.056,,,,,,,0.131,,11.83,PHH,-1.787,0.177985,0.00464313,0.370512 kka2_1:2_L259R,kka2_1:2_259,Kka2,kka2_1:2,P00552,0.37057,NO,259,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.088,-3.982,2.894,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.295029,0.0206964,0.37057 Pab1_L133Q,Pab1_133,Pab1,Pab1,P04147,0.370582,NO,133,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.039,-3.941,2.902,,0.015,,B,1.75,1.03,,,,PHB,-1.22,0.175299,0.000345939,0.370582 kka2_1:1_R202V,kka2_1:1_202,Kka2,kka2_1:1,P00552,0.370584,NO,202,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.761,-3.107,1.346,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.520039,0.00696498,0.370584 kka2_1:2_D208Y,kka2_1:2_208,Kka2,kka2_1:2,P00552,0.370584,NO,208,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.708,-4.416,3.708,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.295029,0.00212588,0.370584 kka2_1:1_I254Y,kka2_1:1_254,Kka2,kka2_1:1,P00552,0.370595,NO,254,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.933,-3.144,1.211,,0.135,H,A,1.52,-0.6,1.859,,71.59,BHH,-1.668,0.520039,0.0132375,0.370595 beta-lactamase_2500_L223Y,beta-lactamase_2500_223,TEM-1,beta-lactamase_2500,P62593,0.370648,NO,223,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.055,-3.889,2.834,,0.27,,B,0.55,0.09,1.334,,74.48,HHO,-1.35033,0.361275,0.00372793,0.370648 beta-lactamase_2500_R242I,beta-lactamase_2500_242,TEM-1,beta-lactamase_2500,P62593,0.37066,NO,242,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.361275,0.00452879,0.37066 kka2_1:2_D190H,kka2_1:2_190,Kka2,kka2_1:2,P00552,0.370825,NO,190,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.708,-4.483,3.775,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.295029,0.00247989,0.370825 kka2_1:2_C192M,kka2_1:2_192,Kka2,kka2_1:2,P00552,0.37087,NO,192,C,M,CM,Special,Hydrophobic,5.07,5.74,0.67,196,121,149,28,108.5,162.9,54.4,-1.067,-4.582,3.515,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.295029,0.00485428,0.37087 kka2_1:1_A247R,kka2_1:1_247,Kka2,kka2_1:1,P00552,0.37088,NO,247,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.459,-3.186,0.727,,1.01,S,A,0.46,0.65,7.731,7.731,92.05,HHH,-2.197,0.520039,0.0102428,0.37088 kka2_1:2_H135Y,kka2_1:2_135,Kka2,kka2_1:2,P00552,0.370916,NO,135,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-1.331,-3.702,2.371,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.295029,0.00532566,0.370916 kka2_1:1_D33K,kka2_1:1_33,Kka2,kka2_1:1,P00552,0.371001,NO,33,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.186,-3.557,1.371,,0.561,S,A,0.75,3.35,2.568,,71.59,PAH,-1.306,0.520039,0.00633568,0.371001 beta-lactamase_I243D,beta-lactamase_243,TEM-1,beta-lactamase,P62593,0.371047,NO,243,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.532,-2.161,0.629,5.26886,,E,B,1.68,-1.24,2.289,,50,OHH,-1.46867,0.221079,0.00464034,0.371047 kka2_1:1_P179W,kka2_1:1_179,Kka2,kka2_1:1,P00552,0.371065,NO,179,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.974,-5.539,4.565,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.520039,0.00298346,0.371065 beta-lactamase_2500_P165Y,beta-lactamase_2500_165,TEM-1,beta-lactamase_2500,P62593,0.371083,NO,165,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.373,-4.331,2.958,,0.203,T,A,0.52,-0.31,0.414,,73.78,AOA,-1.359,0.361275,0.00549538,0.371083 beta-lactamase_2500_Y95S,beta-lactamase_2500_95,TEM-1,beta-lactamase_2500,P62593,0.371094,NO,95,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-1.715,-3.776,2.061,,0.122,,b,0.21,-0.37,2.914,,77.62,BHP,-2.16167,0.361275,0.00479449,0.371094 beta-lactamase_2500_E119Y,beta-lactamase_2500_119,TEM-1,beta-lactamase_2500,P62593,0.371099,NO,119,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.412,-4.336,2.924,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.361275,0.00386966,0.371099 beta-lactamase_625_R220E,beta-lactamase_625_220,TEM-1,beta-lactamase_625,P62593,0.371101,NO,220,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-0.942,-3.264,2.322,,0.295,I,A,1.2,-0.76,5.086,,74.48,HBP,-1.33633,0.213352,0.00232421,0.371101 hsp90_N588I,hsp90_588,hsp90,hsp90,P02829,0.371127,NO,588,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-3.051,-2.939,0,4.61142,0.019,H,A,0.14,0.39,,,,HPH,-3.12167,0.368192,0.000222939,0.371127 beta-lactamase_156_G243Q,beta-lactamase_156_243,TEM-1,beta-lactamase_156,P62593,0.371214,NO,243,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.532,,,,,E,B,0.77,-1.24,2.866,,50,BOH,-1.46867,0.111618,0.00464034,0.371214 kka2_1:4_A224G,kka2_1:4_224,Kka2,kka2_1:4,P00552,0.371297,NO,224,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.977,-3.154,2.177,,,H,A,0.46,-1.26,0.93,,63.64,HHP,-1.41033,0.168804,0.00352047,0.371297 E1_Ubiquitin_R72V,E1_Ubiquitin_72,Uba1,E1_Ubiquitin,P0CG63,0.371353,NO,72,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.184,-3.571,2.387,,0.077,,B,0.16,-0.1,,,,HBH,-1.08733,0.18783,0.00129853,0.371353 kka2_1:8_V97W,kka2_1:8_97,Kka2,kka2_1:8,P00552,0.371359,NO,97,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.453,-5.36,3.907,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.100394,0.00737869,0.371359 kka2_1:8_V97W,kka2_1:8_97,Kka2,kka2_1:8,P00552,0.371359,NO,97,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.453,-5.36,3.907,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.100394,0.00737869,0.371359 Pab1_S154F,Pab1_154,Pab1,Pab1,P04147,0.371463,NO,154,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.146,-3.884,2.738,,0.208,E,B,0.1,-0.75,,,,HPP,-1.408,0.175299,0.000319331,0.371463 kka2_1:8_D261L,kka2_1:8_261,Kka2,kka2_1:8,P00552,0.371471,NO,261,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.708,-3.836,3.128,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.100394,0.0224846,0.371471 kka2_1:8_D261L,kka2_1:8_261,Kka2,kka2_1:8,P00552,0.371471,NO,261,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.708,-3.836,3.128,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.100394,0.0224846,0.371471 kka2_1:4_L158N,kka2_1:4_158,Kka2,kka2_1:4,P00552,0.3715,NO,158,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.947,-4.203,2.256,,0.095,,B,1.59,0.77,7.588,,63.64,AHA,-1.25333,0.168804,0.00529068,0.3715 beta-lactamase_2500_A133E,beta-lactamase_2500_133,TEM-1,beta-lactamase_2500,P62593,0.371549,NO,133,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.186,-3.597,2.411,,,H,A,0.46,-0.86,2.649,,67.83,HHP,-0.988333,0.361275,0.00468022,0.371549 beta-lactamase_39_I280H,beta-lactamase_39_280,TEM-1,beta-lactamase_39,P62593,0.371565,NO,280,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.0495842,0.0530888,0.371565 beta-lactamase_2500_G154M,beta-lactamase_2500_154,TEM-1,beta-lactamase_2500,P62593,0.371608,NO,154,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.823,-4.936,4.113,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.361275,0.00180205,0.371608 beta-lactamase_2500_N152P,beta-lactamase_2500_152,TEM-1,beta-lactamase_2500,P62593,0.371622,NO,152,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-2.757,-3.97,1.213,,0.863,H,A,0.61,0.92,2.061,,77.62,BPH,-2.97,0.361275,0.00471429,0.371622 beta-lactamase_625_S241K,beta-lactamase_625_241,TEM-1,beta-lactamase_625,P62593,0.371628,NO,241,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.213352,0.00452736,0.371628 kka2_1:1_S54N,kka2_1:1_54,Kka2,kka2_1:1,P00552,0.371632,NO,54,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.471,-3.168,0.697,,0.408,S,b,0.27,1.01,6.085,,71.59,HPO,-2.259,0.520039,0.00782867,0.371632 beta-lactamase_2500_K30Y,beta-lactamase_2500_30,TEM-1,beta-lactamase_2500,P62593,0.37164,NO,30,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-2.307,-4.255,1.948,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.361275,0.00448593,0.37164 beta-lactamase_156_T193P,beta-lactamase_156_193,TEM-1,beta-lactamase_156,P62593,0.371675,NO,193,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.914,-4.072,2.158,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.111618,0.00482669,0.371675 beta-lactamase_2500_W208H,beta-lactamase_2500_208,TEM-1,beta-lactamase_2500,P62593,0.371676,NO,208,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-0.818,-4.68,3.862,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.361275,0.00126609,0.371676 beta-lactamase_W227S,beta-lactamase_227,TEM-1,beta-lactamase,P62593,0.371731,NO,227,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-0.982,-3.768,2.786,4.86393,0.272,,B,0.99,-0.29,1.37,,74.48,OHH,-1.595,0.221079,0.00226019,0.371731 kka2_1:1_D101T,kka2_1:1_101,Kka2,kka2_1:1,P00552,0.37174,NO,101,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.028,-3.464,2.436,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.520039,0.00423361,0.37174 kka2_1:2_R258Q,kka2_1:2_258,Kka2,kka2_1:2,P00552,0.371803,NO,258,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.626,-2.106,0.48,,0.316,H,A,1.2,-0.85,7.485,7.485,53.03,HBH,-1.25933,0.295029,0.00983174,0.371803 beta-lactamase_2500_L89E,beta-lactamase_2500_89,TEM-1,beta-lactamase_2500,P62593,0.37186,NO,89,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.096,-3.801,2.705,,0.168,T,A,0.55,0.63,2.066,,64.34,PHO,-1.75767,0.361275,0.00207068,0.37186 kka2_1:1_A56I,kka2_1:1_56,Kka2,kka2_1:1,P00552,0.371958,NO,56,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.083,-3.881,1.798,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.520039,0.00717715,0.371958 beta-lactamase_625_L197W,beta-lactamase_625_197,TEM-1,beta-lactamase_625,P62593,0.371998,NO,197,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.853,-5.146,4.293,,0.007,S,B,0.55,0.33,1.756,,60.14,HHP,-1.833,0.213352,0.00144602,0.371998 beta-lactamase_625_Q204P,beta-lactamase_625_204,TEM-1,beta-lactamase_625,P62593,0.372038,NO,204,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-1.382,-3.857,2.475,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.213352,0.00364106,0.372038 beta-lactamase_2500_D231V,beta-lactamase_2500_231,TEM-1,beta-lactamase_2500,P62593,0.372063,NO,231,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.816,-3.751,2.935,,,E,B,0.75,-1.06,0.319,,65.38,HAB,-0.994,0.361275,0.00107395,0.372063 kka2_1:1_F203N,kka2_1:1_203,Kka2,kka2_1:1,P00552,0.372072,NO,203,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-0.911,-4.185,3.274,,0.26,E,B,0.58,-0.92,7.323,,63.64,BHP,-1.34167,0.520039,0.00318738,0.372072 kka2_1:2_Y257Q,kka2_1:2_257,Kka2,kka2_1:2,P00552,0.372081,NO,257,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-1.064,-4.113,3.049,,0.022,H,A,0.21,-0.88,0.833,,52.65,HHB,-1.39333,0.295029,0.0148191,0.372081 beta-lactamase_2500_D174A,beta-lactamase_2500_174,TEM-1,beta-lactamase_2500,P62593,0.372162,NO,174,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.738,-3.303,2.565,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.361275,0.00125633,0.372162 beta-lactamase_2500_A247N,beta-lactamase_2500_247,TEM-1,beta-lactamase_2500,P62593,0.37221,NO,247,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.361275,0.00611275,0.37221 kka2_1:2_L260D,kka2_1:2_260,Kka2,kka2_1:2,P00552,0.372226,NO,260,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.741,-4.172,3.431,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.295029,0.0233782,0.372226 beta-lactamase_156_A132V,beta-lactamase_156_132,TEM-1,beta-lactamase_156,P62593,0.372273,NO,132,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.9,-2.46,1.56,,,H,A,0.46,-0.93,10.621,,64.69,PHH,-1.138,0.111618,0.000962524,0.372273 beta-lactamase_156_I277H,beta-lactamase_156_277,TEM-1,beta-lactamase_156,P62593,0.372279,NO,277,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.111618,0.0169305,0.372279 beta-lactamase_0_S128Y,beta-lactamase_0_128,TEM-1,beta-lactamase_0,P62593,0.372304,NO,128,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-0.84,-4.162,3.322,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.0500837,0.00071483,0.372304 beta-lactamase_39_L191R,beta-lactamase_39_191,TEM-1,beta-lactamase_39,P62593,0.372309,NO,191,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.087,-4.02,2.933,,,H,A,0.55,0.09,1.372,,63.29,BHH,-1.445,0.0495842,0.00263549,0.372309 beta-lactamase_2500_T139P,beta-lactamase_2500_139,TEM-1,beta-lactamase_2500,P62593,0.372313,NO,139,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.901,-3.919,2.018,,0.216,H,A,0.22,0.39,2.256,,77.62,PPH,-2.04667,0.361275,0.00441837,0.372313 beta-lactamase_F64I,beta-lactamase_64,TEM-1,beta-lactamase,P62593,0.372334,NO,64,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-0.841,-3.335,2.494,5.70769,0.006,E,B,1.33,-0.95,,,,BHO,-0.892667,0.221079,0.000947691,0.372334 kka2_1:1_W91Y,kka2_1:1_91,Kka2,kka2_1:1,P00552,0.37235,NO,91,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-1.178,-2.672,1.494,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.520039,0.00358653,0.37235 kka2_1:2_L193C,kka2_1:2_193,Kka2,kka2_1:2,P00552,0.372372,NO,193,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.983,-4.807,3.824,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.295029,0.00480179,0.372372 kka2_1:4_L212Y,kka2_1:4_212,Kka2,kka2_1:4,P00552,0.372426,NO,212,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.904,-4.048,3.144,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.168804,0.0031426,0.372426 kka2_1:4_S104P,kka2_1:4_104,Kka2,kka2_1:4,P00552,0.372466,NO,104,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.436,-3.932,2.496,,0.536,T,A,0.27,-1.11,0.357,,63.64,HPP,-1.91433,0.168804,0.00555207,0.372466 beta-lactamase_625_V78Y,beta-lactamase_625_78,TEM-1,beta-lactamase_625,P62593,0.372562,NO,78,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.459,-4.112,2.653,,,H,A,0.44,-0.47,2.045,,63.64,HHH,-1.17833,0.213352,0.00492501,0.372562 beta-lactamase_625_M209G,beta-lactamase_625_209,TEM-1,beta-lactamase_625,P62593,0.372598,NO,209,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.442,-3.732,2.29,,,H,A,0.55,-0.97,1.167,,64.69,HHA,-1.52633,0.213352,0.00625021,0.372598 kka2_1:1_M148W,kka2_1:1_148,Kka2,kka2_1:1,P00552,0.372657,NO,148,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.847,-5.364,3.517,,0.268,H,A,1.59,0.71,4.618,,64.39,BHA,-1.65467,0.520039,0.00982664,0.372657 beta-lactamase_2500_E35D,beta-lactamase_2500_35,TEM-1,beta-lactamase_2500,P62593,0.372718,NO,35,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-0.869,-2.219,1.35,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.361275,0.00174441,0.372718 beta-lactamase_R255G,beta-lactamase_255,TEM-1,beta-lactamase,P62593,0.372775,NO,255,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.266,-3.706,1.44,5.55882,0.141,E,B,0.68,0.38,1.199,,63.99,PBH,-2.00433,0.221079,0.00499612,0.372775 kka2_1:1_D157E,kka2_1:1_157,Kka2,kka2_1:1,P00552,0.372807,NO,157,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.993,-2.48,1.487,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.520039,0.0042313,0.372807 beta-lactamase_625_R220D,beta-lactamase_625_220,TEM-1,beta-lactamase_625,P62593,0.372878,NO,220,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-0.942,-3.72,2.778,,0.295,I,A,1.2,-0.76,5.086,,74.48,HBP,-1.33633,0.213352,0.00232421,0.372878 hsp90_F583E,hsp90_583,hsp90,hsp90,P02829,0.372904,NO,583,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-3.22,-2.818,0,5.28185,1.112,S,l,1.1,0.87,,,,PHO,-3.003,0.368192,0.000222939,0.372904 beta-lactamase_625_T69A,beta-lactamase_625_69,TEM-1,beta-lactamase_625,P62593,0.372982,NO,69,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-0.973,-2.115,1.142,,,G,A,0.22,-1.24,2.716,,93.01,PPH,-1.01833,0.213352,0.00127498,0.372982 kka2_1:1_D157F,kka2_1:1_157,Kka2,kka2_1:1,P00552,0.372985,NO,157,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.993,-4.394,3.401,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.520039,0.0042313,0.372985 kka2_1:1_A64G,kka2_1:1_64,Kka2,kka2_1:1,P00552,0.372995,NO,64,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.496,-2.776,1.28,,0.039,H,A,0.46,-0.57,1.175,,56.06,AHH,-1.334,0.520039,0.00705578,0.372995 beta-lactamase_2500_D231N,beta-lactamase_2500_231,TEM-1,beta-lactamase_2500,P62593,0.373015,NO,231,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.816,-3.272,2.456,,,E,B,0.75,-1.06,0.319,,65.38,HAB,-0.994,0.361275,0.00107395,0.373015 beta-lactamase_2500_L100Q,beta-lactamase_2500_100,TEM-1,beta-lactamase_2500,P62593,0.37307,NO,100,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.218,-4.259,3.041,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.361275,0.00413885,0.37307 kka2_1:1_P194N,kka2_1:1_194,Kka2,kka2_1:1,P00552,0.3731,NO,194,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.846,-3.808,2.962,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.520039,0.00314194,0.3731 kka2_1:1_D159N,kka2_1:1_159,Kka2,kka2_1:1,P00552,0.373102,NO,159,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.82,-3.315,2.495,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.520039,0.0030485,0.373102 kka2_1:2_G205F,kka2_1:2_205,Kka2,kka2_1:2,P00552,0.373109,NO,205,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.596,-4.32,3.724,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.295029,0.00221855,0.373109 beta-lactamase_P20W,beta-lactamase_20,TEM-1,beta-lactamase,P62593,0.373127,NO,20,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.74,-5.412,3.672,,,,,,,0.368,,67.83,HOH,-1.765,0.221079,0.00235322,0.373127 beta-lactamase_V31N,beta-lactamase_31,TEM-1,beta-lactamase,P62593,0.373127,NO,31,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.822,-4.194,2.372,5.43781,,H,A,2.78,-0.46,2.885,,73.78,BHB,-2.03767,0.221079,0.00478065,0.373127 kka2_1:2_L123H,kka2_1:2_123,Kka2,kka2_1:2,P00552,0.373195,NO,123,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.888,-4.956,4.068,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.295029,0.00325188,0.373195 beta-lactamase_625_D231F,beta-lactamase_625_231,TEM-1,beta-lactamase_625,P62593,0.373201,NO,231,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.816,-4.318,3.502,,,E,B,0.75,-1.06,1.025,,65.38,HAB,-0.994,0.213352,0.00107395,0.373201 kka2_1:1_D154F,kka2_1:1_154,Kka2,kka2_1:1,P00552,0.373306,NO,154,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.876,-4.375,3.499,,0.457,.,b,0.75,1.48,0.658,,52.65,HAP,-1.52467,0.520039,0.00292633,0.373306 kka2_1:2_C131N,kka2_1:2_131,Kka2,kka2_1:2,P00552,0.373309,NO,131,C,N,CN,Special,Polar,5.07,5.47157,0.401575,139,121,132,11,108.5,114.1,5.6,-0.831,-4.151,3.32,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.295029,0.00170814,0.373309 beta-lactamase_2500_F228G,beta-lactamase_2500_228,TEM-1,beta-lactamase_2500,P62593,0.373347,NO,228,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-2.342,-3.572,1.23,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.361275,0.0046669,0.373347 Pab1_I130H,Pab1_130,Pab1,Pab1,P04147,0.37335,NO,130,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.212,-4.722,3.51,,,E,B,1.23,0.01,,,,HHB,-1.188,0.175299,0.000351112,0.37335 beta-lactamase_156_A235W,beta-lactamase_156_235,TEM-1,beta-lactamase_156,P62593,0.373361,NO,235,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.266,-5.379,4.113,,0.32,E,B,0.46,-0.86,1.344,,50,OHO,-0.89,0.111618,0.00493474,0.373361 beta-lactamase_156_D177G,beta-lactamase_156_177,TEM-1,beta-lactamase_156,P62593,0.373372,NO,177,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.967,-2.392,1.425,,0.006,T,L,0.75,-1.02,2.072,,64.69,BAP,-0.873667,0.111618,0.000864022,0.373372 beta-lactamase_L218W,beta-lactamase_218,TEM-1,beta-lactamase,P62593,0.373381,NO,218,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.391,-5.26,3.869,4.88972,,I,b,2.89,-0.53,12.788,12.788,74.48,OHH,-1.58867,0.221079,0.00618274,0.373381 beta-lactamase_2500_G154P,beta-lactamase_2500_154,TEM-1,beta-lactamase_2500,P62593,0.373387,NO,154,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.823,-3.881,3.058,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.361275,0.00180205,0.373387 kka2_1:1_A129G,kka2_1:1_129,Kka2,kka2_1:1,P00552,0.373484,NO,129,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.656,-2.673,1.017,,0.845,G,A,0.46,0.72,19.686,19.686,92.05,OHP,-1.99,0.520039,0.00726862,0.373484 beta-lactamase_2500_M115S,beta-lactamase_2500_115,TEM-1,beta-lactamase_2500,P62593,0.373527,NO,115,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.389,-3.501,2.112,,0.019,E,B,0.55,0.08,3.261,,69.58,OHP,-1.25433,0.361275,0.0034337,0.373527 beta-lactamase_625_L120G,beta-lactamase_625_120,TEM-1,beta-lactamase_625,P62593,0.37354,NO,120,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.044,-3.788,2.744,,,H,A,0.55,-1.13,7.813,,64.69,AHO,-1.13633,0.213352,0.00143563,0.37354 kka2_1:1_G189D,kka2_1:1_189,Kka2,kka2_1:1,P00552,0.373568,NO,189,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.596,-3.497,2.901,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.520039,0.00253688,0.373568 kka2_1:2_W15Y,kka2_1:2_15,Kka2,kka2_1:2,P00552,0.373578,NO,15,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-1.392,-3.559,2.167,,0.01,G,A,0.47,0.15,2.586,,52.27,HHH,-2.10533,0.295029,0.00585505,0.373578 beta-lactamase_156_W227I,beta-lactamase_156_227,TEM-1,beta-lactamase_156,P62593,0.373638,NO,227,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-0.982,-3.985,3.003,,0.272,,B,0.47,-0.29,2.533,,74.48,OHH,-1.595,0.111618,0.00226019,0.373638 beta-lactamase_625_D48F,beta-lactamase_625_48,TEM-1,beta-lactamase_625,P62593,0.373758,NO,48,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.101,-4.285,3.184,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.213352,0.0027273,0.373758 kka2_1:1_V97A,kka2_1:1_97,Kka2,kka2_1:1,P00552,0.373775,NO,97,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.453,-2.616,1.163,,0.083,,B,1.48,-0.83,13.576,13.576,53.03,AHO,-1.85067,0.520039,0.00737869,0.373775 kka2_1:2_A222Q,kka2_1:2_222,Kka2,kka2_1:2,P00552,0.373869,NO,222,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.725,-3.928,3.203,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.295029,0.00207657,0.373869 beta-lactamase_156_I258N,beta-lactamase_156_258,TEM-1,beta-lactamase_156,P62593,0.373894,NO,258,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.111618,0.007931,0.373894 kka2_1:8_F133K,kka2_1:8_133,Kka2,kka2_1:8,P00552,0.373913,NO,133,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-0.871,-3.933,3.062,,0.178,,B,1.62,0.43,1.816,,42.42,OHA,-0.871667,0.100394,0.00182168,0.373913 kka2_1:8_F133K,kka2_1:8_133,Kka2,kka2_1:8,P00552,0.373913,NO,133,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-0.871,-3.933,3.062,,0.178,,B,1.62,0.43,1.816,,42.42,OHA,-0.871667,0.100394,0.00182168,0.373913 kka2_1:1_D220P,kka2_1:1_220,Kka2,kka2_1:1,P00552,0.373993,NO,220,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.787,-3.727,2.94,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.520039,0.00158066,0.373993 kka2_1:1_D220S,kka2_1:1_220,Kka2,kka2_1:1,P00552,0.373993,NO,220,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.787,-3.25,2.463,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.520039,0.00158066,0.373993 kka2_1:4_L212H,kka2_1:4_212,Kka2,kka2_1:4,P00552,0.373993,NO,212,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.904,-4.956,4.052,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.168804,0.0031426,0.373993 kka2_1:2_G189D,kka2_1:2_189,Kka2,kka2_1:2,P00552,0.373995,NO,189,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.596,-3.497,2.901,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.295029,0.00253688,0.373995 beta-lactamase_2500_A235D,beta-lactamase_2500_235,TEM-1,beta-lactamase_2500,P62593,0.374018,NO,235,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.266,-3.668,2.402,,0.32,E,B,0.46,-0.86,0.891,,50,OHO,-0.89,0.361275,0.00493474,0.374018 kka2_1:8_L102F,kka2_1:8_102,Kka2,kka2_1:8,P00552,0.374024,NO,102,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.804,-3.669,2.865,,,T,A,1.59,-1.17,0.97,,42.42,AHH,-1.398,0.100394,0.00201332,0.374024 kka2_1:8_L102F,kka2_1:8_102,Kka2,kka2_1:8,P00552,0.374024,NO,102,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.804,-3.669,2.865,,,T,A,1.59,-1.17,0.97,,42.42,AHH,-1.398,0.100394,0.00201332,0.374024 beta-lactamase_Y260S,beta-lactamase_260,TEM-1,beta-lactamase,P62593,0.374063,NO,260,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-1.101,-3.675,2.574,5.50878,,E,B,0.73,-1.04,0.865,,60.49,HHP,-1.83433,0.221079,0.00471757,0.374063 beta-lactamase_156_S233Q,beta-lactamase_156_233,TEM-1,beta-lactamase_156,P62593,0.374081,NO,233,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.886,-3.939,2.053,,0.016,E,B,0.27,-1.01,4.111,,77.62,BPO,-1.17267,0.111618,0.00311415,0.374081 kka2_1:4_G210M,kka2_1:4_210,Kka2,kka2_1:4,P00552,0.374086,NO,210,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.095,-4.836,3.741,,0.103,T,A,0.29,-0.62,0.271,,50,OOB,-0.966667,0.168804,0.00598378,0.374086 kka2_1:4_H162I,kka2_1:4_162,Kka2,kka2_1:4,P00552,0.374089,NO,162,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-2.319,-4.138,1.819,,0.071,G,A,0.17,1.01,3.187,,64.39,ABP,-2.02067,0.168804,0.00616145,0.374089 kka2_1:1_A215P,kka2_1:1_215,Kka2,kka2_1:1,P00552,0.374108,NO,215,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.968,-3.768,2.8,,0.039,E,B,0.46,-0.59,0.754,,50.38,HHA,-1.00467,0.520039,0.00529129,0.374108 beta-lactamase_39_A185H,beta-lactamase_39_185,TEM-1,beta-lactamase_39,P62593,0.3742,NO,185,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.406,-4.889,3.483,,,H,A,0.46,-1.02,2.68,,65.03,HHP,-1.84033,0.0495842,0.00467449,0.3742 kka2_1:1_F264W,kka2_1:1_264,Kka2,kka2_1:1,P00552,0.374256,NO,264,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.02,-4.514,3.494,,0.296,.,?,0.58,0.02,2.303,,71.59,HHNA,-0.9655,0.520039,,0.374256 kka2_1:1_I207L,kka2_1:1_207,Kka2,kka2_1:1,P00552,0.374273,NO,207,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.175,-2.098,0.923,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.520039,0.00611824,0.374273 kka2_1:1_V198S,kka2_1:1_198,Kka2,kka2_1:1,P00552,0.374296,NO,198,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.719,-2.746,1.027,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.520039,0.00835002,0.374296 Pab1_I157Y,Pab1_157,Pab1,Pab1,P04147,0.374327,NO,157,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.623,-3.826,2.203,,,,,,,1.439,,79.72,BHH,-1.28667,0.175299,0.0018103,0.374327 kka2_1:1_A224G,kka2_1:1_224,Kka2,kka2_1:1,P00552,0.374379,NO,224,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.977,-3.154,2.177,,,H,A,0.46,-1.26,1.725,,63.64,HHP,-1.41033,0.520039,0.00352047,0.374379 beta-lactamase_625_L218F,beta-lactamase_625_218,TEM-1,beta-lactamase_625,P62593,0.374392,NO,218,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.391,-2.985,1.594,,,I,b,0.55,-0.53,17.202,17.202,74.48,OHH,-1.58867,0.213352,0.00618274,0.374392 beta-lactamase_0_L47C,beta-lactamase_0_47,TEM-1,beta-lactamase_0,P62593,0.374398,NO,47,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.876,-5.002,3.126,,0.007,E,B,0.55,0.2,1.024,,67.83,AHA,-1.639,0.0500837,0.00439844,0.374398 kka2_1:1_K138Y,kka2_1:1_138,Kka2,kka2_1:1,P00552,0.374496,NO,138,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-2.5,-4.407,1.907,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.520039,0.00628542,0.374496 kka2_1:1_Q219I,kka2_1:1_219,Kka2,kka2_1:1,P00552,0.374499,NO,219,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-0.93,-4.062,3.132,,0.088,H,A,0.4,-0.85,1.917,,50,HPA,-1.05167,0.520039,0.00237913,0.374499 kka2_1:1_A9C,kka2_1:1_9,Kka2,kka2_1:1,P00552,0.374536,NO,9,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.079,-4.697,2.618,,,,,,,0.383,,71.59,BHO,-2.253,0.520039,0.00273264,0.374536 kka2_1:4_F240T,kka2_1:4_240,Kka2,kka2_1:4,P00552,0.374578,NO,240,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-0.911,-3.673,2.762,,,H,A,0.58,-1.21,5.798,,50.38,BHH,-1.67267,0.168804,0.00552543,0.374578 beta-lactamase_G239D,beta-lactamase_239,TEM-1,beta-lactamase,P62593,0.374604,NO,239,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.819,-3.459,2.64,4.85529,0.115,T,l,0.77,-0.62,1.817,,42.31,BOP,-1.45267,0.221079,0.00213852,0.374604 kka2_1:2_C209Q,kka2_1:2_209,Kka2,kka2_1:2,P00552,0.374635,NO,209,C,Q,CQ,Special,Polar,5.07,6.24429,1.17429,154,121,146,25,108.5,143.8,35.3,-0.906,-4.376,3.47,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.295029,0.00260862,0.374635 beta-lactamase_625_R59T,beta-lactamase_625_59,TEM-1,beta-lactamase_625,P62593,0.374676,NO,59,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.345,-3.487,2.142,,0.329,S,L,1.2,-0.09,2.995,,73.08,HBO,-2.24267,0.213352,0.00318082,0.374676 kka2_1:4_H135Y,kka2_1:4_135,Kka2,kka2_1:4,P00552,0.374764,NO,135,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-1.331,-3.702,2.371,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.168804,0.00532566,0.374764 kka2_1:1_R145P,kka2_1:1_145,Kka2,kka2_1:1,P00552,0.374804,NO,145,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.804,-4.038,2.234,,0.346,H,A,1.2,1.23,23.699,23.699,63.64,HBP,-1.88033,0.520039,0.00846663,0.374804 beta-lactamase_V214D,beta-lactamase_214,TEM-1,beta-lactamase,P62593,0.374812,NO,214,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.299,-3.873,2.574,5.74008,0.375,S,A,1.19,-0.44,1.899,,74.48,BHH,-1.53733,0.221079,0.00628442,0.374812 beta-lactamase_2500_I54G,beta-lactamase_2500_54,TEM-1,beta-lactamase_2500,P62593,0.374848,NO,54,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-2.838,-3.612,0.774,,0.669,E,B,0.48,-0.14,3.946,,73.78,BHH,-2.337,0.361275,0.00403589,0.374848 beta-lactamase_S240V,beta-lactamase_240,TEM-1,beta-lactamase,P62593,0.374876,NO,240,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.537,-3.433,1.896,4.75024,,,B,0.74,-0.74,0.357,,65.38,OPB,-1.263,0.221079,0.00591201,0.374876 beta-lactamase_2500_R176V,beta-lactamase_2500_176,TEM-1,beta-lactamase_2500,P62593,0.374917,NO,176,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-0.863,-3.754,2.891,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.361275,0.00105554,0.374917 kka2_1:4_L39N,kka2_1:4_39,Kka2,kka2_1:4,P00552,0.374917,NO,39,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.223,-4.209,2.986,,,E,B,0.55,-1.21,1.998,,71.59,BHP,-1.69167,0.168804,0.00493618,0.374917 kka2_1:4_A41P,kka2_1:4_41,Kka2,kka2_1:4,P00552,0.375015,NO,41,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.879,-2.834,0.955,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.168804,0.00543332,0.375015 beta-lactamase_625_I140R,beta-lactamase_625_140,TEM-1,beta-lactamase_625,P62593,0.375033,NO,140,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.733,-4.193,2.46,,0.128,H,A,0.48,0.41,1.628,,73.08,PHO,-1.48733,0.213352,0.00597777,0.375033 beta-lactamase_2500_G114Q,beta-lactamase_2500_114,TEM-1,beta-lactamase_2500,P62593,0.375038,NO,114,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.094,-4.039,2.945,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.361275,0.00224919,0.375038 beta-lactamase_I283P,beta-lactamase_283,TEM-1,beta-lactamase,P62593,0.375159,NO,283,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.638,-4.035,2.397,5.4178,0.165,H,A,1.23,0.04,1.576,,69.23,HHB,-1.735,0.221079,0.0429138,0.375159 kka2_1:2_L57Q,kka2_1:2_57,Kka2,kka2_1:2,P00552,0.375169,NO,57,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.898,-3.254,1.356,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.295029,0.00723769,0.375169 kka2_1:1_L174R,kka2_1:1_174,Kka2,kka2_1:1,P00552,0.375253,NO,174,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.952,-4.019,3.067,,,H,A,0.55,-0.31,13.276,13.276,51.89,BHB,-2.08533,0.520039,0.00438501,0.375253 kka2_1:2_V185G,kka2_1:2_185,Kka2,kka2_1:2,P00552,0.375267,NO,185,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.045,-3.615,2.57,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.295029,0.00367031,0.375267 kka2_1:1_A224K,kka2_1:1_224,Kka2,kka2_1:1,P00552,0.375319,NO,224,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.977,-3.586,2.609,,,H,A,0.46,-1.26,1.725,,63.64,HHP,-1.41033,0.520039,0.00352047,0.375319 hsp90_F583V,hsp90_583,hsp90,hsp90,P02829,0.375367,NO,583,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-3.22,-2.682,0,5.28185,1.112,S,l,1.1,0.87,,,,PHO,-3.003,0.368192,0.000222939,0.375367 beta-lactamase_2500_D83R,beta-lactamase_2500_83,TEM-1,beta-lactamase_2500,P62593,0.375538,NO,83,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.066,-3.889,2.823,,0.354,H,A,0.75,0.22,0.239,,48.95,HAH,-1.34733,0.361275,0.00205968,0.375538 beta-lactamase_2500_V214E,beta-lactamase_2500_214,TEM-1,beta-lactamase_2500,P62593,0.375539,NO,214,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.299,-3.704,2.405,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.361275,0.00628442,0.375539 kka2_1:2_I196E,kka2_1:2_196,Kka2,kka2_1:2,P00552,0.375566,NO,196,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-2.115,-4.03,1.915,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.295029,0.0107273,0.375566 beta-lactamase_625_L135W,beta-lactamase_625_135,TEM-1,beta-lactamase_625,P62593,0.375584,NO,135,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.002,-5.166,4.164,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.213352,0.00244423,0.375584 beta-lactamase_2500_G52Y,beta-lactamase_2500_52,TEM-1,beta-lactamase_2500,P62593,0.375603,NO,52,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.149,-4.436,3.287,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.361275,0.00340138,0.375603 beta-lactamase_156_C75D,beta-lactamase_156_75,TEM-1,beta-lactamase_156,P62593,0.375633,NO,75,C,D,CD,Special,negativeCharge,5.07,5.0516,-0.0184,154,121,133,12,108.5,111.1,2.6,-1.245,-3.832,2.587,,,H,A,0.46,-0.87,0.876,,50,HOO,-1.24333,0.111618,0.0034616,0.375633 kka2_1:1_S54M,kka2_1:1_54,Kka2,kka2_1:1,P00552,0.375652,NO,54,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.471,-4.618,2.147,,0.408,S,b,0.27,1.01,6.085,,71.59,HPO,-2.259,0.520039,0.00782867,0.375652 beta-lactamase_625_I125H,beta-lactamase_625_125,TEM-1,beta-lactamase_625,P62593,0.375656,NO,125,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.441,-4.965,3.524,,,H,A,0.48,-0.7,2.034,,63.29,HHP,-1.248,0.213352,0.00383964,0.375656 beta-lactamase_F14P,beta-lactamase_14,TEM-1,beta-lactamase,P62593,0.375749,NO,14,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-2.736,-2.732,-0.004,,,,,,,1.537,,93.01,HHH,-2.26133,0.221079,0.00277095,0.375749 hsp90_G584N,hsp90_584,hsp90,hsp90,P02829,0.375767,NO,584,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-2.511,-3.051,0,5.20094,0.414,S,b,0.84,0.33,,,,HOH,-3.32733,0.368192,0.000222939,0.375767 kka2_1:2_D208M,kka2_1:2_208,Kka2,kka2_1:2,P00552,0.37577,NO,208,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.708,-4.958,4.25,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.295029,0.00212588,0.37577 kka2_1:1_D154K,kka2_1:1_154,Kka2,kka2_1:1,P00552,0.375777,NO,154,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.876,-3.46,2.584,,0.457,.,b,0.75,1.48,0.658,,52.65,HAP,-1.52467,0.520039,0.00292633,0.375777 beta-lactamase_2500_P181T,beta-lactamase_2500_181,TEM-1,beta-lactamase_2500,P62593,0.375837,NO,181,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.813,-3.419,2.606,,,H,A,0.52,-1.14,1.946,,61.54,HOH,-1.795,0.361275,0.000703122,0.375837 kka2_1:1_P45K,kka2_1:1_45,Kka2,kka2_1:1,P00552,0.37588,NO,45,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.774,-2.635,0.861,,0.669,.,B,0.52,-0.76,4.882,,71.59,BOH,-2.152,0.520039,0.00590481,0.37588 kka2_1:2_R211Y,kka2_1:2_211,Kka2,kka2_1:2,P00552,0.37589,NO,211,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-0.899,-4.076,3.177,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.295029,0.00204888,0.37589 kka2_1:4_L260G,kka2_1:4_260,Kka2,kka2_1:4,P00552,0.375896,NO,260,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.741,-3.836,3.095,,0.022,H,A,0.55,-0.52,,,,HHA,-0.845667,0.168804,0.0233782,0.375896 hsp90_G584K,hsp90_584,hsp90,hsp90,P02829,0.375961,NO,584,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-2.511,-2.835,0,5.20094,0.414,S,b,0.84,0.33,,,,HOH,-3.32733,0.368192,0.000222939,0.375961 beta-lactamase_0_M180D,beta-lactamase_0_180,TEM-1,beta-lactamase_0,P62593,0.376017,NO,180,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-2.795,-3.594,0.799,,0.242,,B,0.55,-0.94,2.892,,77.62,PHO,-1.56433,0.0500837,0.00552048,0.376017 beta-lactamase_2500_T179K,beta-lactamase_2500_179,TEM-1,beta-lactamase_2500,P62593,0.376019,NO,179,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.085,-3.486,2.401,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.361275,0.00226045,0.376019 kka2_1:1_A150G,kka2_1:1_150,Kka2,kka2_1:1,P00552,0.376061,NO,150,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.949,-2.199,1.25,,0.544,T,A,0.46,1.34,2.333,,63.26,AHO,-1.272,0.520039,0.0045009,0.376061 kka2_1:1_I221C,kka2_1:1_221,Kka2,kka2_1:1,P00552,0.376069,NO,221,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.739,-4.79,3.051,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.520039,0.00945908,0.376069 beta-lactamase_L120Y,beta-lactamase_120,TEM-1,beta-lactamase,P62593,0.376082,NO,120,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.044,-3.856,2.812,5.11974,,H,A,1.3,-1.13,1.988,,64.69,AHO,-1.13633,0.221079,0.00143563,0.376082 kka2_1:2_M178S,kka2_1:2_178,Kka2,kka2_1:2,P00552,0.376131,NO,178,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-3.206,-2.817,-0.389,,0.554,.,b,0.55,0.68,3.152,,71.59,BHO,-2.154,0.295029,0.00717253,0.376131 kka2_1:2_R145P,kka2_1:2_145,Kka2,kka2_1:2,P00552,0.376165,NO,145,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.804,-4.038,2.234,,0.346,H,A,1.2,1.23,7.961,,63.64,HBP,-1.88033,0.295029,0.00846663,0.376165 kka2_1:2_D101T,kka2_1:2_101,Kka2,kka2_1:2,P00552,0.376247,NO,101,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.028,-3.464,2.436,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.295029,0.00423361,0.376247 kka2_1:8_V36Q,kka2_1:8_36,Kka2,kka2_1:8,P00552,0.376338,NO,36,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-0.898,-4.235,3.337,,0.292,E,B,1.48,0.21,0.938,,52.27,HHH,-1.484,0.100394,0.00245633,0.376338 kka2_1:8_V36Q,kka2_1:8_36,Kka2,kka2_1:8,P00552,0.376338,NO,36,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-0.898,-4.235,3.337,,0.292,E,B,1.48,0.21,0.938,,52.27,HHH,-1.484,0.100394,0.00245633,0.376338 WW_domain_T196D,WW_domain_196,Yap65,WW_domain,P46937,0.376338,NO,196,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.782,-3.465,1.683,5.5744,,,,,,5.836,,70.04,PPP,-1.732,0.153962,0.00421377,0.376338 beta-lactamase_39_L120W,beta-lactamase_39_120,TEM-1,beta-lactamase_39,P62593,0.376352,NO,120,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.044,-5.142,4.098,,,H,A,0.55,-1.13,22.254,22.254,64.69,AHO,-1.13633,0.0495842,0.00143563,0.376352 beta-lactamase_156_C121F,beta-lactamase_156_121,TEM-1,beta-lactamase_156,P62593,0.376396,NO,121,C,F,CF,Special,Hydrophobic,5.07,3.32051,-1.74949,205,121,165,44,108.5,189.9,81.4,-0.953,-4.116,3.163,,,H,A,0.46,-0.81,1.136,,63.29,HOP,-1.46767,0.111618,0.000744322,0.376396 kka2_1:1_V113D,kka2_1:1_113,Kka2,kka2_1:1,P00552,0.37649,NO,113,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.233,-4.075,2.842,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.520039,0.00650191,0.37649 kka2_1:4_R217Y,kka2_1:4_217,Kka2,kka2_1:4,P00552,0.376539,NO,217,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.158,-4.252,3.094,,0.252,T,A,1.2,-0.59,2.074,,52.27,ABH,-1.127,0.168804,0.0047191,0.376539 beta-lactamase_2500_L89C,beta-lactamase_2500_89,TEM-1,beta-lactamase_2500,P62593,0.37662,NO,89,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.096,-4.756,3.66,,0.168,T,A,0.55,0.63,2.066,,64.34,PHO,-1.75767,0.361275,0.00207068,0.37662 E1_Ubiquitin_I44P,E1_Ubiquitin_44,Uba1,E1_Ubiquitin,P0CG63,0.376658,NO,44,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.432,-3.923,2.491,,,E,B,0.27,-1.17,4.57,,78.74,HHH,-1.25633,0.18783,0.00209731,0.376658 kka2_1:2_W24H,kka2_1:2_24,Kka2,kka2_1:2,P00552,0.376684,NO,24,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-1.779,-4.882,3.103,,0.477,E,B,1.51,-0.21,2.666,,56.06,AHH,-2.24467,0.295029,0.00631564,0.376684 beta-lactamase_2500_I140E,beta-lactamase_2500_140,TEM-1,beta-lactamase_2500,P62593,0.376695,NO,140,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.733,-3.925,2.192,,0.128,H,A,0.48,0.41,1.628,,73.08,PHO,-1.48733,0.361275,0.00597777,0.376695 kka2_1:1_G181F,kka2_1:1_181,Kka2,kka2_1:1,P00552,0.376889,NO,181,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-2.698,-4.379,1.681,,0.379,S,B,0.75,0.78,15.356,15.356,71.59,AOA,-2.21,0.520039,0.00728319,0.376889 beta-lactamase_2500_V42S,beta-lactamase_2500_42,TEM-1,beta-lactamase_2500,P62593,0.376931,NO,42,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.564,-3.633,2.069,,0.017,E,B,0.44,-0.51,1.86,,63.99,BHO,-1.042,0.361275,0.00404515,0.376931 kka2_1:4_D82V,kka2_1:4_82,Kka2,kka2_1:4,P00552,0.376975,NO,82,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.946,-3.073,1.127,,0.341,E,b,0.75,0.52,11.923,11.923,63.64,HAH,-1.98,0.168804,0.00637516,0.376975 beta-lactamase_156_L248Q,beta-lactamase_156_248,TEM-1,beta-lactamase_156,P62593,0.376994,NO,248,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.111618,0.00428493,0.376994 kka2_1:2_D159N,kka2_1:2_159,Kka2,kka2_1:2,P00552,0.377048,NO,159,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.82,-3.315,2.495,,0.28,.,B,0.75,1.25,0.899,,48.11,HAA,-1.48333,0.295029,0.0030485,0.377048 beta-lactamase_625_L79Y,beta-lactamase_625_79,TEM-1,beta-lactamase_625,P62593,0.377058,NO,79,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.842,-3.963,3.121,,0.007,H,A,0.55,-0.16,0.935,,50.35,HHP,-1.44333,0.213352,0.000947397,0.377058 kka2_1:1_R253P,kka2_1:1_253,Kka2,kka2_1:1,P00552,0.377082,NO,253,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.356,-3.924,2.568,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.520039,0.0144195,0.377082 kka2_1:1_Q27S,kka2_1:1_27,Kka2,kka2_1:1,P00552,0.3771,NO,27,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-1.659,-3.464,1.805,,0.608,.,A,0.64,0.71,0.521,,65.53,PPP,-1.90733,0.520039,0.00595365,0.3771 kka2_1:2_Y218V,kka2_1:2_218,Kka2,kka2_1:2,P00552,0.377108,NO,218,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-1.438,-3.601,2.163,,0.122,H,A,0.21,-0.69,1.022,,56.06,BHP,-1.17533,0.295029,0.0126098,0.377108 beta-lactamase_0_A133I,beta-lactamase_0_133,TEM-1,beta-lactamase_0,P62593,0.3772,NO,133,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.186,-3.823,2.637,,,H,A,0.46,-0.86,2.148,,67.83,HHP,-0.988333,0.0500837,0.00468022,0.3772 kka2_1:8_E262N,kka2_1:8_262,Kka2,kka2_1:8,P00552,0.377215,NO,262,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-0.829,-3.499,2.67,,0.059,G,A,1.52,-0.18,0.837,,42.42,AAH,-0.816,0.100394,0.0191586,0.377215 kka2_1:8_E262N,kka2_1:8_262,Kka2,kka2_1:8,P00552,0.377215,NO,262,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-0.829,-3.499,2.67,,0.059,G,A,1.52,-0.18,0.837,,42.42,AAH,-0.816,0.100394,0.0191586,0.377215 Pab1_S154V,Pab1_154,Pab1,Pab1,P04147,0.377219,NO,154,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.146,-3.346,2.2,,0.208,E,B,0.1,-0.75,,,,HPP,-1.408,0.175299,0.000319331,0.377219 PSD95pdz3_H372I,PSD95pdz3_372,PSD95pdz3,PSD95pdz3,P31016,0.377233,NO,372,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-1.627,-3.692,2.065,5.5607,,,,,17.008,,,,PBA,-1.63033,0.0758425,0.00040301,0.377233 kka2_1:2_Y244S,kka2_1:2_244,Kka2,kka2_1:2,P00552,0.377244,NO,244,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-0.775,-3.639,2.864,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.295029,0.00453187,0.377244 kka2_1:2_A215K,kka2_1:2_215,Kka2,kka2_1:2,P00552,0.377245,NO,215,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.968,-3.512,2.544,,0.039,E,B,0.46,-0.59,2.137,,50.38,HHA,-1.00467,0.295029,0.00529129,0.377245 beta-lactamase_625_R176P,beta-lactamase_625_176,TEM-1,beta-lactamase_625,P62593,0.377269,NO,176,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-0.863,-3.88,3.017,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.213352,0.00105554,0.377269 beta-lactamase_2500_L191Q,beta-lactamase_2500_191,TEM-1,beta-lactamase_2500,P62593,0.377296,NO,191,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.087,-4.183,3.096,,,H,A,0.55,0.09,1.703,,63.29,BHH,-1.445,0.361275,0.00263549,0.377296 kka2_1:2_Q27F,kka2_1:2_27,Kka2,kka2_1:2,P00552,0.377411,NO,27,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-1.659,-4.291,2.632,,0.608,.,A,0.64,0.71,0.521,,65.53,PPP,-1.90733,0.295029,0.00595365,0.377411 kka2_1:1_K138F,kka2_1:1_138,Kka2,kka2_1:1,P00552,0.377418,NO,138,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-2.5,-4.458,1.958,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.520039,0.00628542,0.377418 beta-lactamase_156_I258W,beta-lactamase_156_258,TEM-1,beta-lactamase_156,P62593,0.377468,NO,258,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.111618,0.007931,0.377468 kka2_1:1_K175A,kka2_1:1_175,Kka2,kka2_1:1,P00552,0.377538,NO,175,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-2.897,-2.718,-0.179,,0.579,H,A,1.3,0.51,9.33,9.33,71.59,HBH,-1.82333,0.520039,0.00693093,0.377538 kka2_1:1_L39V,kka2_1:1_39,Kka2,kka2_1:1,P00552,0.377574,NO,39,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.223,-2.08,0.857,,,E,B,0.55,-1.21,0.925,,71.59,BHP,-1.69167,0.520039,0.00493618,0.377574 beta-lactamase_2500_D212C,beta-lactamase_2500_212,TEM-1,beta-lactamase_2500,P62593,0.377622,NO,212,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.624,-5.061,3.437,,0.037,,b,0.75,-0.58,12.482,,74.48,HAB,-1.77667,0.361275,0.00644302,0.377622 WW_domain_N191Y,WW_domain_191,Yap65,WW_domain,P46937,0.377652,NO,191,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-1.519,-4.072,2.553,5.96016,,,,,,5.117,,66.07,HPB,-1.554,0.153962,0.00270999,0.377652 kka2_1:2_V153R,kka2_1:2_153,Kka2,kka2_1:2,P00552,0.377738,NO,153,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.092,-4.22,3.128,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.295029,0.00501119,0.377738 beta-lactamase_F70E,beta-lactamase_70,TEM-1,beta-lactamase,P62593,0.377756,NO,70,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.169,-3.82,2.651,5.42055,,H,A,1.1,-1.34,1.14,,63.99,PHB,-0.980667,0.221079,0.00193499,0.377756 kka2_1:2_E142Y,kka2_1:2_142,Kka2,kka2_1:2,P00552,0.377897,NO,142,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.221,-4.391,2.17,,0.471,H,A,1.52,0.85,3.693,,65.53,HAB,-2.08033,0.295029,0.00748883,0.377897 beta-lactamase_625_L218H,beta-lactamase_625_218,TEM-1,beta-lactamase_625,P62593,0.377981,NO,218,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.391,-4.744,3.353,,,I,b,0.55,-0.53,17.202,17.202,74.48,OHH,-1.58867,0.213352,0.00618274,0.377981 beta-lactamase_L79N,beta-lactamase_79,TEM-1,beta-lactamase,P62593,0.377983,NO,79,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.842,-4.12,3.278,4.98681,0.007,H,A,1.07,-0.16,0.823,,50.35,HHP,-1.44333,0.221079,0.000947397,0.377983 kka2_1:2_L212S,kka2_1:2_212,Kka2,kka2_1:2,P00552,0.378054,NO,212,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.904,-3.574,2.67,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.295029,0.0031426,0.378054 kka2_1:8_G210Y,kka2_1:8_210,Kka2,kka2_1:8,P00552,0.378171,NO,210,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.095,-4.42,3.325,,0.103,T,A,0.75,-0.62,2.687,,50,OOB,-0.966667,0.100394,0.00598378,0.378171 kka2_1:8_G210Y,kka2_1:8_210,Kka2,kka2_1:8,P00552,0.378171,NO,210,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.095,-4.42,3.325,,0.103,T,A,0.75,-0.62,2.687,,50,OOB,-0.966667,0.100394,0.00598378,0.378171 kka2_1:8_G189L,kka2_1:8_189,Kka2,kka2_1:8,P00552,0.378199,NO,189,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.596,-3.836,3.24,,0.034,S,l,0.75,-0.99,,,,BOA,-0.739,0.100394,0.00253688,0.378199 kka2_1:8_G189L,kka2_1:8_189,Kka2,kka2_1:8,P00552,0.378199,NO,189,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.596,-3.836,3.24,,0.034,S,l,0.75,-0.99,,,,BOA,-0.739,0.100394,0.00253688,0.378199 beta-lactamase_2500_R257M,beta-lactamase_2500_257,TEM-1,beta-lactamase_2500,P62593,0.378223,NO,257,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.361275,0.00756629,0.378223 beta-lactamase_625_C75N,beta-lactamase_625_75,TEM-1,beta-lactamase_625,P62593,0.37823,NO,75,C,N,CN,Special,Polar,5.07,5.47157,0.401575,139,121,132,11,108.5,114.1,5.6,-1.245,-3.973,2.728,,,H,A,0.46,-0.87,2.141,,50,HOO,-1.24333,0.213352,0.0034616,0.37823 kka2_1:1_H135F,kka2_1:1_135,Kka2,kka2_1:1,P00552,0.378237,NO,135,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-1.331,-4.11,2.779,,0.071,.,a,0.17,0.65,3.574,,53.03,ABP,-1.77367,0.520039,0.00532566,0.378237 beta-lactamase_625_L74D,beta-lactamase_625_74,TEM-1,beta-lactamase_625,P62593,0.378243,NO,74,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.296,-4.023,2.727,,,H,A,0.55,-0.91,0.895,,50,HHO,-1.34933,0.213352,0.00493255,0.378243 beta-lactamase_2500_W227Y,beta-lactamase_2500_227,TEM-1,beta-lactamase_2500,P62593,0.378247,NO,227,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-0.982,-3.356,2.374,,0.272,,B,0.47,-0.29,1.37,,74.48,OHH,-1.595,0.361275,0.00226019,0.378247 kka2_1:4_F48I,kka2_1:4_48,Kka2,kka2_1:4,P00552,0.378308,NO,48,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.453,-2.391,0.938,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.168804,0.00475422,0.378308 beta-lactamase_625_Y262A,beta-lactamase_625_262,TEM-1,beta-lactamase_625,P62593,0.378366,NO,262,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.213352,0.00853516,0.378366 kka2_1:4_V113M,kka2_1:4_113,Kka2,kka2_1:4,P00552,0.378371,NO,113,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.233,-3.136,1.903,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.168804,0.00650191,0.378371 kka2_1:4_V153R,kka2_1:4_153,Kka2,kka2_1:4,P00552,0.378401,NO,153,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.092,-4.22,3.128,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.168804,0.00501119,0.378401 E1_Ubiquitin_L43D,E1_Ubiquitin_43,Uba1,E1_Ubiquitin,P0CG63,0.378426,NO,43,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.188,-3.803,2.615,,,E,B,,-1.17,,,,BHH,-1.30733,0.18783,0.00190185,0.378426 beta-lactamase_A235F,beta-lactamase_235,TEM-1,beta-lactamase,P62593,0.378458,NO,235,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.266,-4.199,2.933,4.83024,0.32,E,B,0.52,-0.86,1.344,,50,OHO,-0.89,0.221079,0.00493474,0.378458 beta-lactamase_G154I,beta-lactamase_154,TEM-1,beta-lactamase,P62593,0.378458,NO,154,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.823,-4.173,3.35,5.40944,0.54,T,l,0.77,-0.56,2.283,,64.69,HOA,-1.635,0.221079,0.00180205,0.378458 beta-lactamase_T69G,beta-lactamase_69,TEM-1,beta-lactamase,P62593,0.378458,NO,69,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-0.973,-3.289,2.316,5.16042,,G,A,0.69,-1.24,0.505,,93.01,PPH,-1.01833,0.221079,0.00127498,0.378458 kka2_1:4_V97D,kka2_1:4_97,Kka2,kka2_1:4,P00552,0.378478,NO,97,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.453,-4.157,2.704,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.168804,0.00737869,0.378478 kka2_1:2_I254Y,kka2_1:2_254,Kka2,kka2_1:2,P00552,0.378484,NO,254,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.933,-3.144,1.211,,0.135,H,A,1.52,-0.6,2.562,,71.59,BHH,-1.668,0.295029,0.0132375,0.378484 kka2_1:1_A35M,kka2_1:1_35,Kka2,kka2_1:1,P00552,0.378572,NO,35,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.127,-3.59,1.463,,0.107,E,B,0.46,1.05,8.405,8.405,71.59,HHH,-1.31767,0.520039,0.00630016,0.378572 beta-lactamase_A235D,beta-lactamase_235,TEM-1,beta-lactamase,P62593,0.378578,NO,235,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.266,-3.668,2.402,4.83024,0.32,E,B,0.52,-0.86,1.344,,50,OHO,-0.89,0.221079,0.00493474,0.378578 beta-lactamase_156_M66E,beta-lactamase_156_66,TEM-1,beta-lactamase_156,P62593,0.37858,NO,66,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.362,-3.832,2.47,,0.013,,A,0.55,-0.7,1.94,,73.08,OHH,-1.49567,0.111618,0.00412876,0.37858 kka2_1:1_V186R,kka2_1:1_186,Kka2,kka2_1:1,P00552,0.378588,NO,186,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.011,-4.25,3.239,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.520039,0.00409703,0.378588 beta-lactamase_625_I93P,beta-lactamase_625_93,TEM-1,beta-lactamase_625,P62593,0.378613,NO,93,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.401,-2.926,1.525,,0.128,E,B,0.48,0.44,1.524,,67.83,BHB,-1.873,0.213352,0.00527066,0.378613 kka2_1:8_C209W,kka2_1:8_209,Kka2,kka2_1:8,P00552,0.378636,NO,209,C,W,CW,Special,Hydrophobic,5.07,5.89,0.82,215,121,204,83,108.5,227.8,119.3,-0.906,-5.149,4.243,,,,a,1.5,-0.89,0.391,,19.32,AOO,-0.903,0.100394,0.00260862,0.378636 kka2_1:8_C209W,kka2_1:8_209,Kka2,kka2_1:8,P00552,0.378636,NO,209,C,W,CW,Special,Hydrophobic,5.07,5.89,0.82,215,121,204,83,108.5,227.8,119.3,-0.906,-5.149,4.243,,,,a,1.5,-0.89,0.391,,19.32,AOO,-0.903,0.100394,0.00260862,0.378636 beta-lactamase_R255F,beta-lactamase_255,TEM-1,beta-lactamase,P62593,0.378651,NO,255,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.266,-2.983,0.717,5.55882,0.141,E,B,0.68,0.38,1.199,,63.99,PBH,-2.00433,0.221079,0.00499612,0.378651 kka2_1:4_I141D,kka2_1:4_141,Kka2,kka2_1:4,P00552,0.378661,NO,141,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.495,-4.166,2.671,,0.068,H,A,0.48,-0.01,2.144,,92.05,BHA,-1.689,0.168804,0.00744745,0.378661 kka2_1:4_G30Y,kka2_1:4_30,Kka2,kka2_1:4,P00552,0.378673,NO,30,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.596,-4.416,3.82,,0.54,S,g,0.29,3.76,,,,HOO,-1.51133,0.168804,0.00159208,0.378673 beta-lactamase_0_T126A,beta-lactamase_0_126,TEM-1,beta-lactamase_0,P62593,0.378695,NO,126,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.122,-2.955,1.833,,0.05,H,A,0.22,-0.05,0.705,,44.41,HPH,-1.60467,0.0500837,0.00244552,0.378695 beta-lactamase_2500_N134D,beta-lactamase_2500_134,TEM-1,beta-lactamase_2500,P62593,0.378706,NO,134,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-0.879,-3.087,2.208,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.361275,0.000644786,0.378706 kka2_1:2_E63V,kka2_1:2_63,Kka2,kka2_1:2,P00552,0.378717,NO,63,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-0.762,-3.557,2.795,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.295029,0.00118399,0.378717 beta-lactamase_2500_L192S,beta-lactamase_2500_192,TEM-1,beta-lactamase_2500,P62593,0.378822,NO,192,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.254,-3.616,2.362,,0.095,H,A,0.55,0.35,1.902,,60.14,HHP,-1.41833,0.361275,0.00558728,0.378822 beta-lactamase_I229W,beta-lactamase_229,TEM-1,beta-lactamase,P62593,0.378828,NO,229,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.267,-5.365,4.098,5.0911,0.083,E,B,1,-0.76,1.114,,50,HHH,-1.58767,0.221079,0.00477249,0.378828 kka2_1:1_A9D,kka2_1:1_9,Kka2,kka2_1:1,P00552,0.378852,NO,9,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.079,-3.62,1.541,,,,,,,0.383,,71.59,BHO,-2.253,0.520039,0.00273264,0.378852 kka2_1:1_G164A,kka2_1:1_164,Kka2,kka2_1:1,P00552,0.378899,NO,164,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.869,-3.006,2.137,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.520039,0.00442091,0.378899 kka2_1:2_E231G,kka2_1:2_231,Kka2,kka2_1:2,P00552,0.378917,NO,231,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.002,-3.247,1.245,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.295029,0.00732383,0.378917 beta-lactamase_625_A215L,beta-lactamase_625_215,TEM-1,beta-lactamase_625,P62593,0.378941,NO,215,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.503,-3.475,1.972,,,,a,0.46,-0.93,3.583,,74.48,HHO,-1.42633,0.213352,0.00544007,0.378941 beta-lactamase_W286R,beta-lactamase_286,TEM-1,beta-lactamase,P62593,0.378977,NO,286,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-1.111,-3.975,2.864,6.64456,0.492,,?,0.01,0.6,,,,BHX,-1.478,0.221079,,0.378977 Ubiquitin_G10E,Ubiquitin_10,Uba1,Ubiquitin,P0CG48,0.379032,NO,10,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.396,-2.47,1.074,5.29806,0.115,S,l,,0.2,,,,POB,-1.38633,0.205827,0.000748953,0.379032 Ubiquitin_K27V,Ubiquitin_27,Uba1,Ubiquitin,P0CG48,0.379032,NO,27,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.064,-3.582,2.518,4.77438,0.086,H,A,2.89,-0.74,2.662,,27.01,HBH,-1.42667,0.205827,0.000767556,0.379032 Ubiquitin_L69S,Ubiquitin_69,Uba1,Ubiquitin,P0CG48,0.379032,NO,69,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.445,-2.836,1.391,4.75624,0.051,E,B,2.89,-0.94,7.106,,34.31,BHH,-1.72933,0.205827,0.000919136,0.379032 Ubiquitin_R42I,Ubiquitin_42,Uba1,Ubiquitin,P0CG48,0.379032,NO,42,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.571,-3.947,2.376,5.07805,0.244,E,B,0.68,-0.54,1.976,,72.85,PBH,-1.38967,0.205827,0.000622265,0.379032 Ubiquitin_V70M,Ubiquitin_70,Uba1,Ubiquitin,P0CG48,0.379032,NO,70,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.874,-3.284,1.41,5.29728,0.05,E,B,0.96,-0.97,2.363,,34.31,HHH,-1.65533,0.205827,0.00106871,0.379032 kka2_1:1_S105K,kka2_1:1_105,Kka2,kka2_1:1,P00552,0.379075,NO,105,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.945,-3.628,1.683,,0.056,S,B,0.27,-1.04,3.442,,65.53,PPB,-2.17033,0.520039,0.00847233,0.379075 kka2_1:4_E182I,kka2_1:4_182,Kka2,kka2_1:4,P00552,0.379098,NO,182,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.516,-4.087,2.571,,0.326,.,B,1.04,0.75,4.755,,65.53,OAA,-1.806,0.168804,0.00641548,0.379098 Pab1_N127R,Pab1_127,Pab1,Pab1,P04147,0.379163,NO,127,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-1.079,-3.3,2.221,,0.138,E,B,1.05,-0.51,,,,OPH,-1.13633,0.175299,0.000805159,0.379163 kka2_1:2_S104V,kka2_1:2_104,Kka2,kka2_1:2,P00552,0.37921,NO,104,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.436,-2.726,1.29,,0.536,T,A,0.27,-1.11,5.49,,63.64,HPP,-1.91433,0.295029,0.00555207,0.37921 beta-lactamase_2500_R220P,beta-lactamase_2500_220,TEM-1,beta-lactamase_2500,P62593,0.379214,NO,220,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-0.942,-3.877,2.935,,0.295,I,A,1.2,-0.76,2.175,,74.48,HBP,-1.33633,0.361275,0.00232421,0.379214 kka2_1:1_C192Q,kka2_1:1_192,Kka2,kka2_1:1,P00552,0.379368,NO,192,C,Q,CQ,Special,Polar,5.07,6.24429,1.17429,154,121,146,25,108.5,143.8,35.3,-1.067,-4.263,3.196,,0.095,.,B,0.46,-0.75,2.749,,50,HOH,-0.960333,0.520039,0.00485428,0.379368 hsp90_E590K,hsp90_590,hsp90,hsp90,P02829,0.379396,NO,590,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.818,-2.835,0,4.65049,0.021,H,A,,0.03,,,,HAO,-3.338,0.368192,0.000222939,0.379396 kka2_1:8_W236S,kka2_1:8_236,Kka2,kka2_1:8,P00552,0.379398,NO,236,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-1.363,-3.736,2.373,,0.303,H,A,1.51,-0.76,1.87,,48.48,AHH,-1.81267,0.100394,0.0088796,0.379398 kka2_1:8_W236S,kka2_1:8_236,Kka2,kka2_1:8,P00552,0.379398,NO,236,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-1.363,-3.736,2.373,,0.303,H,A,1.51,-0.76,1.87,,48.48,AHH,-1.81267,0.100394,0.0088796,0.379398 beta-lactamase_625_A235K,beta-lactamase_625_235,TEM-1,beta-lactamase_625,P62593,0.379467,NO,235,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.266,-3.575,2.309,,0.32,E,B,0.46,-0.86,0.281,,50,OHO,-0.89,0.213352,0.00493474,0.379467 beta-lactamase_2500_R242P,beta-lactamase_2500_242,TEM-1,beta-lactamase_2500,P62593,0.379475,NO,242,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.361275,0.00452879,0.379475 kka2_1:2_V80K,kka2_1:2_80,Kka2,kka2_1:2,P00552,0.379523,NO,80,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.144,-3.802,2.658,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.295029,0.00488211,0.379523 kka2_1:4_V186M,kka2_1:4_186,Kka2,kka2_1:4,P00552,0.379562,NO,186,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.011,-4.138,3.127,,,E,B,0.44,-0.61,0.679,,45.83,HHP,-1.10967,0.168804,0.00409703,0.379562 beta-lactamase_2500_S68N,beta-lactamase_2500_68,TEM-1,beta-lactamase_2500,P62593,0.379584,NO,68,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-0.913,-2.44,1.527,,0.064,G,A,0.27,-1.03,2.824,,64.69,HPP,-1.37233,0.361275,0.000800065,0.379584 beta-lactamase_G239T,beta-lactamase_239,TEM-1,beta-lactamase,P62593,0.379613,NO,239,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.819,-3.558,2.739,4.85529,0.115,T,l,0.77,-0.62,1.817,,42.31,BOP,-1.45267,0.221079,0.00213852,0.379613 kka2_1:4_G99F,kka2_1:4_99,Kka2,kka2_1:4,P00552,0.379641,NO,99,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.596,-4.32,3.724,,0.368,S,g,0.29,-0.87,,,,OOP,-1.63067,0.168804,0.00186055,0.379641 kka2_1:2_L241C,kka2_1:2_241,Kka2,kka2_1:2,P00552,0.379762,NO,241,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.158,-3.073,1.915,,0.08,H,A,0.55,-0.82,1.598,,63.26,HHH,-1.58533,0.295029,0.0117299,0.379762 kka2_1:8_N195W,kka2_1:8_195,Kka2,kka2_1:8,P00552,0.379771,NO,195,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-0.836,-5.599,4.763,,0.037,G,A,0.43,-1.36,1.108,,48.11,OPH,-1.26567,0.100394,0.00276134,0.379771 kka2_1:8_N195W,kka2_1:8_195,Kka2,kka2_1:8,P00552,0.379771,NO,195,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-0.836,-5.599,4.763,,0.037,G,A,0.43,-1.36,1.108,,48.11,OPH,-1.26567,0.100394,0.00276134,0.379771 beta-lactamase_2500_D231K,beta-lactamase_2500_231,TEM-1,beta-lactamase_2500,P62593,0.379781,NO,231,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.816,-3.42,2.604,,,E,B,0.75,-1.06,0.319,,65.38,HAB,-0.994,0.361275,0.00107395,0.379781 kka2_1:2_A25P,kka2_1:2_25,Kka2,kka2_1:2,P00552,0.379813,NO,25,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.496,-3.994,1.498,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.295029,0.00595636,0.379813 kka2_1:4_L223T,kka2_1:4_223,Kka2,kka2_1:4,P00552,0.379823,NO,223,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.861,-3.494,2.633,,,H,A,1.59,-1.24,1.268,,50,HHH,-0.854333,0.168804,0.00253574,0.379823 kka2_1:8_D261M,kka2_1:8_261,Kka2,kka2_1:8,P00552,0.379833,NO,261,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.708,-4.958,4.25,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.100394,0.0224846,0.379833 kka2_1:8_D261M,kka2_1:8_261,Kka2,kka2_1:8,P00552,0.379833,NO,261,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.708,-4.958,4.25,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.100394,0.0224846,0.379833 kka2_1:1_L158G,kka2_1:1_158,Kka2,kka2_1:1,P00552,0.379834,NO,158,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.947,-3.704,1.757,,0.095,.,B,0.55,0.77,7.588,,63.64,AHA,-1.25333,0.520039,0.00529068,0.379834 beta-lactamase_2500_T131N,beta-lactamase_2500_131,TEM-1,beta-lactamase_2500,P62593,0.379851,NO,131,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.328,-3.603,2.275,,,H,A,0.22,-0.69,3.048,,67.48,PPH,-1.00867,0.361275,0.00345886,0.379851 kka2_1:2_S105P,kka2_1:2_105,Kka2,kka2_1:2,P00552,0.379922,NO,105,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.945,-3.155,1.21,,0.056,S,B,0.27,-1.04,3.442,,65.53,PPB,-2.17033,0.295029,0.00847233,0.379922 beta-lactamase_2500_L218P,beta-lactamase_2500_218,TEM-1,beta-lactamase_2500,P62593,0.379944,NO,218,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.391,-4.052,2.661,,,I,b,0.55,-0.53,9.151,9.151,74.48,OHH,-1.58867,0.361275,0.00618274,0.379944 kka2_1:1_G43M,kka2_1:1_43,Kka2,kka2_1:1,P00552,0.379959,NO,43,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.587,-4.94,3.353,,0.862,T,l,0.75,-0.67,2.247,,63.26,POB,-2.18533,0.520039,0.0071925,0.379959 kka2_1:2_L152D,kka2_1:2_152,Kka2,kka2_1:2,P00552,0.379963,NO,152,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.521,-3.958,2.437,,0.547,.,A,0.55,1.36,4.526,,63.64,OHH,-1.162,0.295029,0.00674868,0.379963 beta-lactamase_156_N134L,beta-lactamase_156_134,TEM-1,beta-lactamase_156,P62593,0.379988,NO,134,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-0.879,-3.581,2.702,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.111618,0.000644786,0.379988 beta-lactamase_2500_T116R,beta-lactamase_2500_116,TEM-1,beta-lactamase_2500,P62593,0.380022,NO,116,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.28,-2.627,1.347,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.361275,0.00336175,0.380022 kka2_1:1_V214A,kka2_1:1_214,Kka2,kka2_1:1,P00552,0.38005,NO,214,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.261,-3.113,1.852,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.520039,0.00692782,0.38005 beta-lactamase_2500_E56W,beta-lactamase_2500_56,TEM-1,beta-lactamase_2500,P62593,0.380065,NO,56,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.043,-5.293,3.25,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.361275,0.00238534,0.380065 kka2_1:1_R147P,kka2_1:1_147,Kka2,kka2_1:1,P00552,0.380086,NO,147,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.123,-3.991,2.868,,0.094,H,A,1.2,0.97,2.578,,64.02,PBH,-1.98267,0.520039,0.00549168,0.380086 kka2_1:1_D156P,kka2_1:1_156,Kka2,kka2_1:1,P00552,0.380098,NO,156,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.696,-3.904,2.208,,0.884,T,A,0.75,1.87,1.044,,65.53,PAA,-1.765,0.520039,0.00926998,0.380098 E1_Ubiquitin_R72Y,E1_Ubiquitin_72,Uba1,E1_Ubiquitin,P0CG63,0.380195,NO,72,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.184,-3.98,2.796,,0.077,,B,0.16,-0.1,,,,HBH,-1.08733,0.18783,0.00129853,0.380195 beta-lactamase_2500_T178Q,beta-lactamase_2500_178,TEM-1,beta-lactamase_2500,P62593,0.380208,NO,178,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-0.791,-3.899,3.108,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.361275,0.000684366,0.380208 beta-lactamase_L223E,beta-lactamase_223,TEM-1,beta-lactamase,P62593,0.38021,NO,223,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.055,-3.868,2.813,5.42318,0.27,,B,1.3,0.09,1.511,,74.48,HHO,-1.35033,0.221079,0.00372793,0.38021 kka2_1:1_L243H,kka2_1:1_243,Kka2,kka2_1:1,P00552,0.380357,NO,243,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-2.651,-3.263,0.612,,0.277,H,A,0.55,-0.67,4.334,,92.05,HHH,-2.03767,0.520039,0.00884927,0.380357 kka2_1:8_D227L,kka2_1:8_227,Kka2,kka2_1:8,P00552,0.38039,NO,227,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.758,-3.54,1.782,,0.128,H,A,0.75,-0.63,0.281,,56.06,BAH,-1.43067,0.100394,0.00745029,0.38039 kka2_1:8_D227L,kka2_1:8_227,Kka2,kka2_1:8,P00552,0.38039,NO,227,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.758,-3.54,1.782,,0.128,H,A,0.75,-0.63,0.281,,56.06,BAH,-1.43067,0.100394,0.00745029,0.38039 beta-lactamase_156_M209V,beta-lactamase_156_209,TEM-1,beta-lactamase_156,P62593,0.380403,NO,209,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.442,-2.446,1.004,,,H,A,0.55,-0.97,1.066,,64.69,HHA,-1.52633,0.111618,0.00625021,0.380403 beta-lactamase_P65M,beta-lactamase_65,TEM-1,beta-lactamase,P62593,0.380573,NO,65,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.894,-4.494,3.6,5.59094,0.098,E,B,0.23,-0.62,0.623,,40.56,HOH,-1.03233,0.221079,0.00152776,0.380573 kka2_1:1_E111R,kka2_1:1_111,Kka2,kka2_1:1,P00552,0.380656,NO,111,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.28,-2.316,0.036,,0.155,H,A,1.52,-1.14,15.716,15.716,65.53,HAB,-2.27833,0.520039,0.00746789,0.380656 beta-lactamase_2500_R159G,beta-lactamase_2500_159,TEM-1,beta-lactamase_2500,P62593,0.38068,NO,159,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-0.94,-3.384,2.444,,0.316,,B,1.2,-0.55,2.341,,64.34,PBH,-1.011,0.361275,0.00108472,0.38068 kka2_1:1_M148N,kka2_1:1_148,Kka2,kka2_1:1,P00552,0.380688,NO,148,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.847,-4.17,2.323,,0.268,H,A,1.59,0.71,4.618,,64.39,BHA,-1.65467,0.520039,0.00982664,0.380688 kka2_1:1_V153F,kka2_1:1_153,Kka2,kka2_1:1,P00552,0.380691,NO,153,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.092,-3.89,2.798,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.520039,0.00501119,0.380691 kka2_1:1_K175D,kka2_1:1_175,Kka2,kka2_1:1,P00552,0.380803,NO,175,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-2.897,-3.874,0.977,,0.579,H,A,1.3,0.51,9.33,9.33,71.59,HBH,-1.82333,0.520039,0.00693093,0.380803 beta-lactamase_2500_D36P,beta-lactamase_2500_36,TEM-1,beta-lactamase_2500,P62593,0.380867,NO,36,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.732,-3.967,1.235,,0.555,H,A,0.75,1.17,2.26,,77.62,AAP,-1.91167,0.361275,0.00476483,0.380867 kka2_1:8_D208L,kka2_1:8_208,Kka2,kka2_1:8,P00552,0.380917,NO,208,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.708,-3.836,3.128,,0.36,,l,0.29,-1.01,,,,HAO,-0.929667,0.100394,0.00212588,0.380917 kka2_1:8_D208L,kka2_1:8_208,Kka2,kka2_1:8,P00552,0.380917,NO,208,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.708,-3.836,3.128,,0.36,,l,0.29,-1.01,,,,HAO,-0.929667,0.100394,0.00212588,0.380917 beta-lactamase_2500_R242A,beta-lactamase_2500_242,TEM-1,beta-lactamase_2500,P62593,0.380973,NO,242,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.361275,0.00452879,0.380973 kka2_1:1_G201N,kka2_1:1_201,Kka2,kka2_1:1,P00552,0.380979,NO,201,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.56,-2.642,1.082,,0.149,T,l,0.29,-0.57,16.092,16.092,52.65,POB,-1.92233,0.520039,0.00820117,0.380979 kka2_1:2_G189T,kka2_1:2_189,Kka2,kka2_1:2,P00552,0.381049,NO,189,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.596,-3.675,3.079,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.295029,0.00253688,0.381049 beta-lactamase_2500_R220T,beta-lactamase_2500_220,TEM-1,beta-lactamase_2500,P62593,0.381055,NO,220,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-0.942,-3.419,2.477,,0.295,I,A,1.2,-0.76,2.175,,74.48,HBP,-1.33633,0.361275,0.00232421,0.381055 beta-lactamase_2500_A215D,beta-lactamase_2500_215,TEM-1,beta-lactamase_2500,P62593,0.381068,NO,215,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.503,-3.621,2.118,,,,a,0.46,-0.93,3.516,,74.48,HHO,-1.42633,0.361275,0.00544007,0.381068 beta-lactamase_2500_G154F,beta-lactamase_2500_154,TEM-1,beta-lactamase_2500,P62593,0.381086,NO,154,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.823,-4.328,3.505,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.361275,0.00180205,0.381086 beta-lactamase_2500_L248K,beta-lactamase_2500_248,TEM-1,beta-lactamase_2500,P62593,0.381101,NO,248,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.361275,0.00428493,0.381101 beta-lactamase_L218R,beta-lactamase_218,TEM-1,beta-lactamase,P62593,0.381142,NO,218,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.391,-2.276,0.885,4.88972,,I,b,2.89,-0.53,12.788,12.788,74.48,OHH,-1.58867,0.221079,0.00618274,0.381142 beta-lactamase_2500_V259F,beta-lactamase_2500_259,TEM-1,beta-lactamase_2500,P62593,0.381155,NO,259,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.361275,0.0070773,0.381155 kka2_1:1_E230P,kka2_1:1_230,Kka2,kka2_1:1,P00552,0.381216,NO,230,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.672,-4.133,1.461,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.520039,0.00920051,0.381216 beta-lactamase_156_G249Y,beta-lactamase_156_249,TEM-1,beta-lactamase_156,P62593,0.381295,NO,249,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.111618,0.00220169,0.381295 kka2_1:1_P128R,kka2_1:1_128,Kka2,kka2_1:1,P00552,0.381337,NO,128,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.922,-4.235,2.313,,0.316,G,A,0.52,0.4,2.178,,56.06,AOH,-1.64733,0.520039,0.00774689,0.381337 kka2_1:2_L174S,kka2_1:2_174,Kka2,kka2_1:2,P00552,0.38134,NO,174,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.952,-3.62,2.668,,,H,A,1.59,-0.31,8.521,,51.89,BHB,-2.08533,0.295029,0.00438501,0.38134 kka2_1:2_K50L,kka2_1:2_50,Kka2,kka2_1:2,P00552,0.381398,NO,50,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-0.833,-3.41,2.577,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.295029,0.00138626,0.381398 kka2_1:2_R44T,kka2_1:2_44,Kka2,kka2_1:2,P00552,0.381407,NO,44,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.062,-3.662,1.6,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.295029,0.00745043,0.381407 kka2_1:2_T51Y,kka2_1:2_51,Kka2,kka2_1:2,P00552,0.381454,NO,51,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.199,-4.283,2.084,,0.05,E,B,0.22,-0.05,13.165,13.165,63.64,BPA,-1.76767,0.295029,0.00628861,0.381454 kka2_1:8_F37G,kka2_1:8_37,Kka2,kka2_1:8,P00552,0.381458,NO,37,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.427,-3.622,2.195,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.100394,0.00586193,0.381458 kka2_1:8_F37G,kka2_1:8_37,Kka2,kka2_1:8,P00552,0.381458,NO,37,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.427,-3.622,2.195,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.100394,0.00586193,0.381458 kka2_1:1_D261T,kka2_1:1_261,Kka2,kka2_1:1,P00552,0.381554,NO,261,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.708,-3.45,2.742,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.520039,0.0224846,0.381554 kka2_1:4_L123S,kka2_1:4_123,Kka2,kka2_1:4,P00552,0.381581,NO,123,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.888,-3.661,2.773,,0.007,H,A,0.55,-0.4,1.447,,48.86,BHB,-1.301,0.168804,0.00325188,0.381581 beta-lactamase_2500_L197N,beta-lactamase_2500_197,TEM-1,beta-lactamase_2500,P62593,0.381596,NO,197,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.853,-4.12,3.267,,0.007,S,B,0.55,0.33,2.421,,60.14,HHP,-1.833,0.361275,0.00144602,0.381596 kka2_1:1_A34P,kka2_1:1_34,Kka2,kka2_1:1,P00552,0.381597,NO,34,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.928,-3.715,2.787,,0.417,.,B,0.46,2.29,0.262,,52.27,AHH,-1.747,0.520039,0.00343484,0.381597 kka2_1:1_A14G,kka2_1:1_14,Kka2,kka2_1:1,P00552,0.381607,NO,14,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.837,-2.323,0.486,,0.728,G,A,0.46,0.7,1.17,,71.59,HHH,-1.82567,0.520039,0.00706614,0.381607 kka2_1:2_K112D,kka2_1:2_112,Kka2,kka2_1:2,P00552,0.381622,NO,112,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-2.491,-3.95,1.459,,0.076,H,A,2.34,-1.37,23.433,23.433,56.06,ABH,-2.00133,0.295029,0.00645389,0.381622 kka2_1:4_R217Q,kka2_1:4_217,Kka2,kka2_1:4,P00552,0.381641,NO,217,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.158,-2.901,1.743,,0.252,T,A,1.2,-0.59,2.074,,52.27,ABH,-1.127,0.168804,0.0047191,0.381641 kka2_1:8_D261Q,kka2_1:8_261,Kka2,kka2_1:8,P00552,0.381674,NO,261,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.708,-3.703,2.995,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.100394,0.0224846,0.381674 kka2_1:8_D261Q,kka2_1:8_261,Kka2,kka2_1:8,P00552,0.381674,NO,261,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.708,-3.703,2.995,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.100394,0.0224846,0.381674 kka2_1:1_W91H,kka2_1:1_91,Kka2,kka2_1:1,P00552,0.381714,NO,91,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-1.178,-4.573,3.395,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.520039,0.00358653,0.381714 kka2_1:1_W91V,kka2_1:1_91,Kka2,kka2_1:1,P00552,0.381714,NO,91,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-1.178,-3.738,2.56,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.520039,0.00358653,0.381714 kka2_1:1_D250I,kka2_1:1_250,Kka2,kka2_1:1,P00552,0.381844,NO,250,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.015,-4.121,3.106,,0.274,.,b,0.75,-0.46,4.177,,51.89,OAP,-1.83933,0.520039,0.0177103,0.381844 kka2_1:1_P12V,kka2_1:1_12,Kka2,kka2_1:1,P00552,0.381877,NO,12,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.853,-3.479,2.626,,,.,B,0.52,1.25,0.261,,48.11,POH,-1.80767,0.520039,0.00500011,0.381877 kka2_1:1_V97D,kka2_1:1_97,Kka2,kka2_1:1,P00552,0.381911,NO,97,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.453,-4.157,2.704,,0.083,,B,1.48,-0.83,13.576,13.576,53.03,AHO,-1.85067,0.520039,0.00737869,0.381911 kka2_1:2_A224N,kka2_1:2_224,Kka2,kka2_1:2,P00552,0.381952,NO,224,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.977,-3.898,2.921,,,H,A,0.46,-1.26,1.646,,63.64,HHP,-1.41033,0.295029,0.00352047,0.381952 beta-lactamase_625_L219T,beta-lactamase_625_219,TEM-1,beta-lactamase_625,P62593,0.382009,NO,219,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.313,-3.55,2.237,,,I,A,0.55,-0.51,5.627,,74.48,HHB,-1.21533,0.213352,0.00664345,0.382009 beta-lactamase_2500_K30F,beta-lactamase_2500_30,TEM-1,beta-lactamase_2500,P62593,0.382204,NO,30,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-2.307,-4.338,2.031,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.361275,0.00448593,0.382204 kka2_1:1_D261H,kka2_1:1_261,Kka2,kka2_1:1,P00552,0.382275,NO,261,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.708,-4.483,3.775,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.520039,0.0224846,0.382275 kka2_1:1_Q100S,kka2_1:1_100,Kka2,kka2_1:1,P00552,0.382283,NO,100,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.77,-2.33,-0.44,,0.646,E,B,0.4,-0.79,15.116,15.116,71.59,OPA,-1.46467,0.520039,0.0066405,0.382283 beta-lactamase_625_T263P,beta-lactamase_625_263,TEM-1,beta-lactamase_625,P62593,0.382335,NO,263,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.213352,0.0110582,0.382335 beta-lactamase_625_D212L,beta-lactamase_625_212,TEM-1,beta-lactamase_625,P62593,0.382358,NO,212,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.624,-3.598,1.974,,0.037,,b,0.75,-0.58,1.516,,74.48,HAB,-1.77667,0.213352,0.00644302,0.382358 beta-lactamase_156_S233L,beta-lactamase_156_233,TEM-1,beta-lactamase_156,P62593,0.382476,NO,233,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.886,-3.357,1.471,,0.016,E,B,0.27,-1.01,4.111,,77.62,BPO,-1.17267,0.111618,0.00311415,0.382476 kka2_1:1_A168F,kka2_1:1_168,Kka2,kka2_1:1,P00552,0.382479,NO,168,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.989,-3.458,1.469,,0.67,H,A,0.46,0.15,25.546,25.546,64.39,OHA,-2.12933,0.520039,0.00806773,0.382479 kka2_1:8_M197G,kka2_1:8_197,Kka2,kka2_1:8,P00552,0.382537,NO,197,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.707,-3.845,2.138,,0.121,E,B,1.59,-1.19,4.408,,65.53,HHH,-1.847,0.100394,0.00921295,0.382537 kka2_1:8_M197G,kka2_1:8_197,Kka2,kka2_1:8,P00552,0.382537,NO,197,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.707,-3.845,2.138,,0.121,E,B,1.59,-1.19,4.408,,65.53,HHH,-1.847,0.100394,0.00921295,0.382537 kka2_1:1_R38Q,kka2_1:1_38,Kka2,kka2_1:1,P00552,0.382561,NO,38,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.207,-3.749,2.542,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.520039,0.00372499,0.382561 kka2_1:4_F133R,kka2_1:4_133,Kka2,kka2_1:4,P00552,0.382574,NO,133,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-0.871,-4.184,3.313,,0.178,.,B,0.58,0.43,0.786,,42.42,OHA,-0.871667,0.168804,0.00182168,0.382574 kka2_1:8_Y22D,kka2_1:8_22,Kka2,kka2_1:8,P00552,0.382645,NO,22,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-1.583,-3.909,2.326,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.100394,0.00598977,0.382645 kka2_1:8_Y22D,kka2_1:8_22,Kka2,kka2_1:8,P00552,0.382645,NO,22,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-1.583,-3.909,2.326,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.100394,0.00598977,0.382645 beta-lactamase_2500_R257A,beta-lactamase_2500_257,TEM-1,beta-lactamase_2500,P62593,0.382669,NO,257,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.361275,0.00756629,0.382669 kka2_1:2_W91N,kka2_1:2_91,Kka2,kka2_1:2,P00552,0.382671,NO,91,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-1.178,-4.186,3.008,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.295029,0.00358653,0.382671 beta-lactamase_625_T147F,beta-lactamase_625_147,TEM-1,beta-lactamase_625,P62593,0.382797,NO,147,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.149,-4.147,2.998,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.213352,0.00226017,0.382797 kka2_1:2_R258C,kka2_1:2_258,Kka2,kka2_1:2,P00552,0.382877,NO,258,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.626,-2.089,0.463,,0.316,H,A,1.2,-0.85,7.485,7.485,53.03,HBH,-1.25933,0.295029,0.00983174,0.382877 beta-lactamase_A235K,beta-lactamase_235,TEM-1,beta-lactamase,P62593,0.3829,NO,235,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.266,-3.575,2.309,4.83024,0.32,E,B,0.52,-0.86,1.344,,50,OHO,-0.89,0.221079,0.00493474,0.3829 beta-lactamase_C75N,beta-lactamase_75,TEM-1,beta-lactamase,P62593,0.3829,NO,75,C,N,CN,Special,Polar,5.07,5.47157,0.401575,139,121,132,11,108.5,114.1,5.6,-1.245,-3.973,2.728,4.88171,,H,A,0.25,-0.87,0.876,,50,HOO,-1.24333,0.221079,0.0034616,0.3829 beta-lactamase_V258N,beta-lactamase_258,TEM-1,beta-lactamase,P62593,0.3829,NO,258,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.975,-3.914,1.939,5.16083,,E,B,1.64,-1.02,2.124,,67.83,HHH,-1.67667,0.221079,0.007931,0.3829 beta-lactamase_V42H,beta-lactamase_42,TEM-1,beta-lactamase,P62593,0.3829,NO,42,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.564,-4.991,3.427,5.27904,0.017,E,B,1.64,-0.51,2.024,,63.99,BHO,-1.042,0.221079,0.00404515,0.3829 kka2_1:2_R253G,kka2_1:2_253,Kka2,kka2_1:2,P00552,0.382966,NO,253,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.356,-3.453,2.097,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.295029,0.0144195,0.382966 kka2_1:4_A117E,kka2_1:4_117,Kka2,kka2_1:4,P00552,0.382968,NO,117,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.828,-3.532,2.704,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.168804,0.00282984,0.382968 kka2_1:2_A144F,kka2_1:2_144,Kka2,kka2_1:2,P00552,0.383011,NO,144,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.859,-4.095,3.236,,,H,A,0.46,0.21,6.844,,52.65,BHB,-1.72933,0.295029,0.00231095,0.383011 kka2_1:2_A144H,kka2_1:2_144,Kka2,kka2_1:2,P00552,0.383011,NO,144,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.859,-4.791,3.932,,,H,A,0.46,0.21,6.844,,52.65,BHB,-1.72933,0.295029,0.00231095,0.383011 kka2_1:1_A87L,kka2_1:1_87,Kka2,kka2_1:1,P00552,0.383042,NO,87,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.917,-3.08,1.163,,1.039,S,L,0.46,1.57,20.738,20.738,65.53,AHO,-1.822,0.520039,0.00791281,0.383042 kka2_1:1_Y218V,kka2_1:1_218,Kka2,kka2_1:1,P00552,0.383123,NO,218,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-1.438,-3.601,2.163,,0.122,H,A,1.25,-0.69,3.059,,56.06,BHP,-1.17533,0.520039,0.0126098,0.383123 kka2_1:8_L123A,kka2_1:8_123,Kka2,kka2_1:8,P00552,0.383183,NO,123,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.888,-3.161,2.273,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.100394,0.00325188,0.383183 kka2_1:8_L123A,kka2_1:8_123,Kka2,kka2_1:8,P00552,0.383183,NO,123,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.888,-3.161,2.273,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.100394,0.00325188,0.383183 beta-lactamase_2500_N168V,beta-lactamase_2500_168,TEM-1,beta-lactamase_2500,P62593,0.383285,NO,168,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-1.029,-3.632,2.603,,0.113,G,A,0.61,-0.4,2.9,,44.41,HPA,-1.13233,0.361275,0.00288667,0.383285 kka2_1:1_G10M,kka2_1:1_10,Kka2,kka2_1:1,P00552,0.383326,NO,10,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.921,-4.699,2.778,,,,,,,1.862,,71.59,HOP,-2.10733,0.520039,0.00289233,0.383326 kka2_1:2_F203C,kka2_1:2_203,Kka2,kka2_1:2,P00552,0.383347,NO,203,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-0.911,-4.889,3.978,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.295029,0.00318738,0.383347 kka2_1:4_P98Y,kka2_1:4_98,Kka2,kka2_1:4,P00552,0.383389,NO,98,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.526,-4.481,2.955,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.168804,0.00622754,0.383389 kka2_1:4_L184D,kka2_1:4_184,Kka2,kka2_1:4,P00552,0.383397,NO,184,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.496,-4.1,2.604,,0.489,E,B,1.59,-0.06,4.495,,63.26,AHH,-1.24833,0.168804,0.00518742,0.383397 kka2_1:1_M178A,kka2_1:1_178,Kka2,kka2_1:1,P00552,0.383439,NO,178,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-3.206,-2.643,-0.563,,0.554,.,b,0.55,0.68,3.152,,71.59,BHO,-2.154,0.520039,0.00717253,0.383439 beta-lactamase_I243H,beta-lactamase_243,TEM-1,beta-lactamase,P62593,0.383466,NO,243,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.532,-4.725,3.193,5.26886,,E,B,1.68,-1.24,2.289,,50,OHH,-1.46867,0.221079,0.00464034,0.383466 beta-lactamase_156_W208R,beta-lactamase_156_208,TEM-1,beta-lactamase_156,P62593,0.3835,NO,208,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-0.818,-4.158,3.34,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.111618,0.00126609,0.3835 beta-lactamase_I229N,beta-lactamase_229,TEM-1,beta-lactamase,P62593,0.383728,NO,229,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.267,-4.128,2.861,5.0911,0.083,E,B,1,-0.76,1.114,,50,HHH,-1.58767,0.221079,0.00477249,0.383728 beta-lactamase_0_M180I,beta-lactamase_0_180,TEM-1,beta-lactamase_0,P62593,0.383764,NO,180,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-2.795,-3.664,0.869,,0.242,,B,0.55,-0.94,2.892,,77.62,PHO,-1.56433,0.0500837,0.00552048,0.383764 kka2_1:1_G88N,kka2_1:1_88,Kka2,kka2_1:1,P00552,0.383917,NO,88,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.689,-2.869,1.18,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.520039,0.00685559,0.383917 kka2_1:4_F171C,kka2_1:4_171,Kka2,kka2_1:4,P00552,0.383952,NO,171,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.326,-4.966,3.64,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.168804,0.00821426,0.383952 beta-lactamase_625_L223H,beta-lactamase_625_223,TEM-1,beta-lactamase_625,P62593,0.383974,NO,223,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.055,-4.894,3.839,,0.27,,B,0.55,0.09,1.633,,74.48,HHO,-1.35033,0.213352,0.00372793,0.383974 beta-lactamase_2500_A235C,beta-lactamase_2500_235,TEM-1,beta-lactamase_2500,P62593,0.383994,NO,235,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.266,-4.693,3.427,,0.32,E,B,0.46,-0.86,0.891,,50,OHO,-0.89,0.361275,0.00493474,0.383994 kka2_1:2_A108I,kka2_1:2_108,Kka2,kka2_1:2,P00552,0.384033,NO,108,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.061,-3.962,1.901,,0.243,.,B,0.46,-1.34,2.462,,71.59,HHO,-1.57033,0.295029,0.00751209,0.384033 kka2_1:1_W69P,kka2_1:1_69,Kka2,kka2_1:1,P00552,0.384048,NO,69,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-0.859,-4.356,3.497,,0.164,H,A,0.47,0.15,5.074,,38.64,PHH,-1.49967,0.520039,0.0012874,0.384048 kka2_1:8_F48K,kka2_1:8_48,Kka2,kka2_1:8,P00552,0.38406,NO,48,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.453,-3.972,2.519,,0.296,E,B,1.62,-0.99,14.194,14.194,55.3,HHH,-1.444,0.100394,0.00475422,0.38406 kka2_1:8_F48K,kka2_1:8_48,Kka2,kka2_1:8,P00552,0.38406,NO,48,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.453,-3.972,2.519,,0.296,E,B,1.62,-0.99,14.194,14.194,55.3,HHH,-1.444,0.100394,0.00475422,0.38406 beta-lactamase_625_N274K,beta-lactamase_625_274,TEM-1,beta-lactamase_625,P62593,0.384169,NO,274,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.213352,0.0110418,0.384169 kka2_1:2_H124I,kka2_1:2_124,Kka2,kka2_1:2,P00552,0.384217,NO,124,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-0.84,-4.039,3.199,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.295029,0.00211296,0.384217 kka2_1:2_P109Y,kka2_1:2_109,Kka2,kka2_1:2,P00552,0.384229,NO,109,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.412,-4.295,2.883,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.295029,0.0070929,0.384229 beta-lactamase_39_D129G,beta-lactamase_39_129,TEM-1,beta-lactamase_39,P62593,0.384233,NO,129,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.816,-3.182,2.366,,,,B,0.75,-0.69,0.56,,34.97,PAP,-0.818,0.0495842,0.00109178,0.384233 kka2_1:4_R258N,kka2_1:4_258,Kka2,kka2_1:4,P00552,0.38429,NO,258,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.626,-3.818,2.192,,0.316,H,A,1.2,-0.85,2.655,,53.03,HBH,-1.25933,0.168804,0.00983174,0.38429 beta-lactamase_156_C121N,beta-lactamase_156_121,TEM-1,beta-lactamase_156,P62593,0.384381,NO,121,C,N,CN,Special,Polar,5.07,5.47157,0.401575,139,121,132,11,108.5,114.1,5.6,-0.953,-4.045,3.092,,,H,A,0.46,-0.81,1.136,,63.29,HOP,-1.46767,0.111618,0.000744322,0.384381 kka2_1:1_A65P,kka2_1:1_65,Kka2,kka2_1:1,P00552,0.384472,NO,65,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.744,-4.019,2.275,,0.437,H,A,0.46,-0.39,3.012,,63.64,HHB,-1.38733,0.520039,0.00709258,0.384472 beta-lactamase_2500_A133V,beta-lactamase_2500_133,TEM-1,beta-lactamase_2500,P62593,0.384507,NO,133,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.186,-3.341,2.155,,,H,A,0.46,-0.86,2.649,,67.83,HHP,-0.988333,0.361275,0.00468022,0.384507 kka2_1:1_H139G,kka2_1:1_139,Kka2,kka2_1:1,P00552,0.384621,NO,139,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-2.809,-2.92,0.111,,0.471,H,A,0.17,0.68,1.153,,63.64,BBB,-2.22,0.520039,0.00734779,0.384621 kka2_1:2_V83P,kka2_1:2_83,Kka2,kka2_1:2,P00552,0.384789,NO,83,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-2.567,-4.134,1.567,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.295029,0.00650486,0.384789 kka2_1:1_P132M,kka2_1:1_132,Kka2,kka2_1:1,P00552,0.384812,NO,132,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.775,-4.731,3.956,,0.692,.,A,0.52,0.56,0.224,,44.7,OOH,-0.825667,0.520039,0.0018489,0.384812 kka2_1:4_R122N,kka2_1:4_122,Kka2,kka2_1:4,P00552,0.384829,NO,122,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.175,-2.97,0.795,,0.487,H,A,0.16,0.26,16.436,16.436,71.59,BBH,-1.53833,0.168804,0.00736512,0.384829 kka2_1:4_I207S,kka2_1:4_207,Kka2,kka2_1:4,P00552,0.384841,NO,207,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.175,-3.726,2.551,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.168804,0.00611824,0.384841 kka2_1:4_H188M,kka2_1:4_188,Kka2,kka2_1:4,P00552,0.38485,NO,188,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-0.913,-4.701,3.788,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.168804,0.00273139,0.38485 kka2_1:2_D82K,kka2_1:2_82,Kka2,kka2_1:2,P00552,0.384862,NO,82,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.946,-3.004,1.058,,0.341,E,b,0.75,0.52,11.923,11.923,63.64,HAH,-1.98,0.295029,0.00637516,0.384862 beta-lactamase_625_P224Y,beta-lactamase_625_224,TEM-1,beta-lactamase_625,P62593,0.384893,NO,224,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.893,-4.387,3.494,,0.383,,B,0.52,-0.3,1.35,,74.48,HOH,-1.26433,0.213352,0.00189564,0.384893 kka2_1:8_A34L,kka2_1:8_34,Kka2,kka2_1:8,P00552,0.384899,NO,34,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.928,-3.244,2.316,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.100394,0.00343484,0.384899 kka2_1:8_A34L,kka2_1:8_34,Kka2,kka2_1:8,P00552,0.384899,NO,34,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.928,-3.244,2.316,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.100394,0.00343484,0.384899 kka2_1:2_L184V,kka2_1:2_184,Kka2,kka2_1:2,P00552,0.384902,NO,184,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.496,-2.642,1.146,,0.489,E,B,0.55,-0.06,14.044,14.044,63.26,AHH,-1.24833,0.295029,0.00518742,0.384902 beta-lactamase_2500_I229F,beta-lactamase_2500_229,TEM-1,beta-lactamase_2500,P62593,0.384919,NO,229,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.267,-3.792,2.525,,0.083,E,B,0.48,-0.76,3.875,,50,HHH,-1.58767,0.361275,0.00477249,0.384919 kka2_1:1_Q163C,kka2_1:1_163,Kka2,kka2_1:1,P00552,0.384938,NO,163,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.162,-5.049,2.887,,0.58,T,B,0.64,1.85,2.779,,64.02,BPO,-1.78333,0.520039,0.00719507,0.384938 beta-lactamase_2500_I285H,beta-lactamase_2500_285,TEM-1,beta-lactamase_2500,P62593,0.38497,NO,285,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.845,-3.788,1.943,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.361275,0.101555,0.38497 beta-lactamase_625_E35K,beta-lactamase_625_35,TEM-1,beta-lactamase_625,P62593,0.384985,NO,35,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-0.869,-3.075,2.206,,0.15,H,A,1.04,0.21,0.664,,46.85,HAA,-1.88667,0.213352,0.00174441,0.384985 kka2_1:1_A129L,kka2_1:1_129,Kka2,kka2_1:1,P00552,0.385033,NO,129,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.656,-3.565,1.909,,0.845,G,A,0.46,0.72,19.686,19.686,92.05,OHP,-1.99,0.520039,0.00726862,0.385033 kka2_1:1_N195V,kka2_1:1_195,Kka2,kka2_1:1,P00552,0.385065,NO,195,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-0.836,-3.805,2.969,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.520039,0.00276134,0.385065 kka2_1:2_R140Q,kka2_1:2_140,Kka2,kka2_1:2,P00552,0.385096,NO,140,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.351,-2.5,1.149,,0.12,H,A,1.2,0.2,0.352,,53.03,BBH,-1.885,0.295029,0.00430167,0.385096 kka2_1:8_D220F,kka2_1:8_220,Kka2,kka2_1:8,P00552,0.385113,NO,220,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.787,-4.288,3.501,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.100394,0.00158066,0.385113 kka2_1:8_D220F,kka2_1:8_220,Kka2,kka2_1:8,P00552,0.385113,NO,220,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.787,-4.288,3.501,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.100394,0.00158066,0.385113 kka2_1:1_G30Y,kka2_1:1_30,Kka2,kka2_1:1,P00552,0.385172,NO,30,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.596,-4.416,3.82,,0.54,S,g,0.29,3.76,,,,HOO,-1.51133,0.520039,0.00159208,0.385172 kka2_1:1_G43P,kka2_1:1_43,Kka2,kka2_1:1,P00552,0.385207,NO,43,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.587,-4.038,2.451,,0.862,T,l,0.75,-0.67,2.247,,63.26,POB,-2.18533,0.520039,0.0071925,0.385207 kka2_1:1_V185G,kka2_1:1_185,Kka2,kka2_1:1,P00552,0.385218,NO,185,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.045,-3.615,2.57,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.520039,0.00367031,0.385218 kka2_1:1_R38V,kka2_1:1_38,Kka2,kka2_1:1,P00552,0.385226,NO,38,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.207,-2.691,1.484,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.520039,0.00372499,0.385226 kka2_1:4_A34P,kka2_1:4_34,Kka2,kka2_1:4,P00552,0.385243,NO,34,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.928,-3.715,2.787,,0.417,.,B,0.46,2.29,0.262,,52.27,AHH,-1.747,0.168804,0.00343484,0.385243 Pab1_A182D,Pab1_182,Pab1,Pab1,P04147,0.385325,NO,182,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.013,-3.511,2.498,,,H,A,0.17,0.79,,,,AHH,-1.36067,0.175299,0.000289034,0.385325 kka2_1:1_Y257Q,kka2_1:1_257,Kka2,kka2_1:1,P00552,0.385348,NO,257,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-1.064,-4.113,3.049,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.520039,0.0148191,0.385348 kka2_1:2_I228M,kka2_1:2_228,Kka2,kka2_1:2,P00552,0.385408,NO,228,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.142,-4.08,2.938,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.295029,0.00458834,0.385408 kka2_1:4_D220R,kka2_1:4_220,Kka2,kka2_1:4,P00552,0.385413,NO,220,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.787,-4.005,3.218,,,H,A,0.75,-1.14,1.237,,46.59,PAH,-1.152,0.168804,0.00158066,0.385413 beta-lactamase_625_E35H,beta-lactamase_625_35,TEM-1,beta-lactamase_625,P62593,0.385414,NO,35,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-0.869,-4.279,3.41,,0.15,H,A,1.04,0.21,0.664,,46.85,HAA,-1.88667,0.213352,0.00174441,0.385414 beta-lactamase_E87R,beta-lactamase_87,TEM-1,beta-lactamase,P62593,0.385425,NO,87,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.421,-3.739,2.318,5.41929,0.048,,B,0.52,0.92,1.754,,64.69,PAP,-1.969,0.221079,0.00337888,0.385425 PSD95pdz3_I336G,PSD95pdz3_336,PSD95pdz3,PSD95pdz3,P31016,0.385459,NO,336,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.63,-3.49,1.86,5.11321,,,,,13.6363,,,,OHH,-1.38733,0.0758425,0.000887923,0.385459 Pab1_V171P,Pab1_171,Pab1,Pab1,P04147,0.385477,NO,171,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.113,-3.697,2.584,,0.008,E,b,0.23,-0.34,,,,HHB,-1.19733,0.175299,0.000298662,0.385477 E1_Ubiquitin_F45P,E1_Ubiquitin_45,Uba1,E1_Ubiquitin,P0CG63,0.3855,NO,45,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.149,-4.147,2.998,,0.26,E,B,,-0.99,,,,HHH,-1.316,0.18783,0.00193245,0.3855 beta-lactamase_2500_G240E,beta-lactamase_2500_240,TEM-1,beta-lactamase_2500,P62593,0.385598,NO,240,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.361275,0.00591201,0.385598 beta-lactamase_39_P181H,beta-lactamase_39_181,TEM-1,beta-lactamase_39,P62593,0.385626,NO,181,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.813,-4.706,3.893,,,H,A,0.52,-1.14,1.946,,61.54,HOH,-1.795,0.0495842,0.000703122,0.385626 kka2_1:4_G233S,kka2_1:4_233,Kka2,kka2_1:4,P00552,0.385663,NO,233,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.748,-3.234,2.486,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.168804,0.00232366,0.385663 gb1_F278C,gb1_278,gb1,gb1,P06654,0.385848,NO,278,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.418,-4.812,3.394,,,,,,,3.233,,35.71,PHP,-1.503,0.177985,0.00295699,0.385848 gb1_F278H,gb1_278,gb1,gb1,P06654,0.385848,NO,278,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.418,-4.226,2.808,,,,,,,3.233,,35.71,PHP,-1.503,0.177985,0.00295699,0.385848 gb1_N234P,gb1_234,gb1,gb1,P06654,0.385848,NO,234,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-2.055,-3.617,1.562,,,,,,,1.235,,45.54,HPO,-2.05067,0.177985,0.00242189,0.385848 kka2_1:8_L123Q,kka2_1:8_123,Kka2,kka2_1:8,P00552,0.385861,NO,123,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.888,-4.152,3.264,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.100394,0.00325188,0.385861 kka2_1:8_L123Q,kka2_1:8_123,Kka2,kka2_1:8,P00552,0.385861,NO,123,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.888,-4.152,3.264,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.100394,0.00325188,0.385861 beta-lactamase_2500_E164D,beta-lactamase_2500_164,TEM-1,beta-lactamase_2500,P62593,0.385957,NO,164,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-0.948,-2.949,2.001,,0.011,T,B,1.04,-0.4,0.352,,64.69,HAO,-1.388,0.361275,0.00137286,0.385957 kka2_1:1_H162I,kka2_1:1_162,Kka2,kka2_1:1,P00552,0.386002,NO,162,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-2.319,-4.138,1.819,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.520039,0.00616145,0.386002 kka2_1:1_G55M,kka2_1:1_55,Kka2,kka2_1:1,P00552,0.38605,NO,55,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.625,-3.536,1.911,,0.517,S,b,0.29,1.19,4.035,,63.64,POH,-2.05967,0.520039,0.00667877,0.38605 beta-lactamase_2500_T158C,beta-lactamase_2500_158,TEM-1,beta-lactamase_2500,P62593,0.386061,NO,158,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.116,-4.748,3.632,,0.036,,B,0.22,-0.85,1.344,,69.58,HPB,-1.269,0.361275,0.00341825,0.386061 kka2_1:1_L259R,kka2_1:1_259,Kka2,kka2_1:1,P00552,0.38608,NO,259,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.088,-3.982,2.894,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.520039,0.0206964,0.38608 beta-lactamase_0_M115W,beta-lactamase_0_115,TEM-1,beta-lactamase_0,P62593,0.386127,NO,115,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.389,-5.031,3.642,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.0500837,0.0034337,0.386127 kka2_1:1_S104P,kka2_1:1_104,Kka2,kka2_1:1,P00552,0.386168,NO,104,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.436,-3.932,2.496,,0.536,T,A,0.27,-1.11,5.49,,63.64,HPP,-1.91433,0.520039,0.00555207,0.386168 beta-lactamase_T147F,beta-lactamase_147,TEM-1,beta-lactamase,P62593,0.38627,NO,147,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.149,-4.147,2.998,5.37474,0.281,H,A,0.8,-0.68,2.838,,64.34,HPH,-1.456,0.221079,0.00226017,0.38627 beta-lactamase_625_A185T,beta-lactamase_625_185,TEM-1,beta-lactamase_625,P62593,0.386429,NO,185,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.406,-2.128,0.722,,,H,A,0.46,-1.02,0.365,,65.03,HHP,-1.84033,0.213352,0.00467449,0.386429 hsp90_M589R,hsp90_589,hsp90,hsp90,P02829,0.386611,NO,589,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-3.858,-3.086,0,4.72723,0.032,H,A,0.84,0.31,,,,PHA,-3.24233,0.368192,0.000222939,0.386611 Pab1_S147P,Pab1_147,Pab1,Pab1,P04147,0.386637,NO,147,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.267,-3.525,2.258,,0.336,H,A,,0.56,,,,HPH,-1.43033,0.175299,0.000610856,0.386637 kka2_1:4_R145I,kka2_1:4_145,Kka2,kka2_1:4,P00552,0.386683,NO,145,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.804,-4.111,2.307,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.168804,0.00846663,0.386683 beta-lactamase_625_P105C,beta-lactamase_625_105,TEM-1,beta-lactamase_625,P62593,0.386686,NO,105,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.813,-5.05,4.237,,0.226,T,A,0.52,0.8,1.154,,63.29,POH,-1.01533,0.213352,0.0011981,0.386686 beta-lactamase_2500_A235E,beta-lactamase_2500_235,TEM-1,beta-lactamase_2500,P62593,0.386687,NO,235,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.266,-3.558,2.292,,0.32,E,B,0.46,-0.86,0.891,,50,OHO,-0.89,0.361275,0.00493474,0.386687 beta-lactamase_R59T,beta-lactamase_59,TEM-1,beta-lactamase,P62593,0.386696,NO,59,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.345,-3.487,2.142,5.49837,0.329,S,L,0.68,-0.09,1.806,,73.08,HBO,-2.24267,0.221079,0.00318082,0.386696 beta-lactamase_625_T179Y,beta-lactamase_625_179,TEM-1,beta-lactamase_625,P62593,0.386733,NO,179,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.085,-4.097,3.012,,,E,B,0.22,-1.38,0.367,,73.08,PPH,-1.557,0.213352,0.00226045,0.386733 beta-lactamase_625_P65L,beta-lactamase_625_65,TEM-1,beta-lactamase_625,P62593,0.386745,NO,65,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.894,-2.247,1.353,,0.098,E,B,0.52,-0.62,0.3,,40.56,HOH,-1.03233,0.213352,0.00152776,0.386745 kka2_1:2_D159F,kka2_1:2_159,Kka2,kka2_1:2,P00552,0.386868,NO,159,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.82,-4.355,3.535,,0.28,.,B,0.75,1.25,0.899,,48.11,HAA,-1.48333,0.295029,0.0030485,0.386868 kka2_1:4_L158K,kka2_1:4_158,Kka2,kka2_1:4,P00552,0.386882,NO,158,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.947,-3.896,1.949,,0.095,,B,1.59,0.77,7.588,,63.64,AHA,-1.25333,0.168804,0.00529068,0.386882 kka2_1:1_I221F,kka2_1:1_221,Kka2,kka2_1:1,P00552,0.387077,NO,221,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.739,-3.76,2.021,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.520039,0.00945908,0.387077 Ubiquitin_I13W,Ubiquitin_13,Uba1,Ubiquitin,P0CG48,0.387097,NO,13,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.554,-5.105,3.551,5.19411,0.038,E,B,,-0.2,,,,PHP,-1.48,0.205827,0.000716423,0.387097 Ubiquitin_L67Q,Ubiquitin_67,Uba1,Ubiquitin,P0CG48,0.387097,NO,67,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.435,-3.03,1.595,4.92156,,E,B,1.19,-1.02,6.371,6.371,30.8,PHB,-1.628,0.205827,0.000482727,0.387097 Ubiquitin_T7I,Ubiquitin_7,Uba1,Ubiquitin,P0CG48,0.387097,NO,7,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.415,-2.264,0.849,4.954,0.094,E,B,0.43,-0.78,0.805,,21.31,BPH,-1.41033,0.205827,0.000647855,0.387097 beta-lactamase_625_N274M,beta-lactamase_625_274,TEM-1,beta-lactamase_625,P62593,0.387125,NO,274,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.213352,0.0110418,0.387125 beta-lactamase_625_N134Q,beta-lactamase_625_134,TEM-1,beta-lactamase_625,P62593,0.387131,NO,134,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-0.879,-3.672,2.793,,0.138,H,A,0.61,-0.6,3.776,,53.15,HPH,-1.02233,0.213352,0.000644786,0.387131 kka2_1:1_D216T,kka2_1:1_216,Kka2,kka2_1:1,P00552,0.387168,NO,216,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.785,-3.493,2.708,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.520039,0.00229969,0.387168 kka2_1:2_G213D,kka2_1:2_213,Kka2,kka2_1:2,P00552,0.387177,NO,213,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.596,-3.497,2.901,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.295029,0.00187654,0.387177 kka2_1:2_L170H,kka2_1:2_170,Kka2,kka2_1:2,P00552,0.387253,NO,170,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.28,-5.007,3.727,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.295029,0.00730791,0.387253 E1_Ubiquitin_R72I,E1_Ubiquitin_72,Uba1,E1_Ubiquitin,P0CG63,0.387268,NO,72,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.184,-3.827,2.643,,0.077,,B,0.16,-0.1,,,,HBH,-1.08733,0.18783,0.00129853,0.387268 kka2_1:4_L259H,kka2_1:4_259,Kka2,kka2_1:4,P00552,0.387269,NO,259,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.088,-4.939,3.851,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.168804,0.0206964,0.387269 kka2_1:1_D82L,kka2_1:1_82,Kka2,kka2_1:1,P00552,0.387314,NO,82,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.946,-3.65,1.704,,0.341,E,b,0.75,0.52,11.345,11.345,63.64,HAH,-1.98,0.520039,0.00637516,0.387314 kka2_1:1_D82R,kka2_1:1_82,Kka2,kka2_1:1,P00552,0.387314,NO,82,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.946,-2.957,1.011,,0.341,E,b,0.75,0.52,11.345,11.345,63.64,HAH,-1.98,0.520039,0.00637516,0.387314 beta-lactamase_2500_D231H,beta-lactamase_2500_231,TEM-1,beta-lactamase_2500,P62593,0.387434,NO,231,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.816,-4.453,3.637,,,E,B,0.75,-1.06,0.319,,65.38,HAB,-0.994,0.361275,0.00107395,0.387434 beta-lactamase_L218E,beta-lactamase_218,TEM-1,beta-lactamase,P62593,0.387499,NO,218,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.391,-3.611,2.22,4.88972,,I,b,2.89,-0.53,12.788,12.788,74.48,OHH,-1.58867,0.221079,0.00618274,0.387499 beta-lactamase_156_F64T,beta-lactamase_156_64,TEM-1,beta-lactamase_156,P62593,0.387537,NO,64,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-0.841,-3.646,2.805,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.111618,0.000947691,0.387537 kka2_1:1_E59F,kka2_1:1_59,Kka2,kka2_1:1,P00552,0.387559,NO,59,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-0.952,-4.364,3.412,,0.187,.,L,1.04,0.62,2.648,,50.38,PAH,-1.53,0.520039,0.00280355,0.387559 kka2_1:4_V36D,kka2_1:4_36,Kka2,kka2_1:4,P00552,0.387563,NO,36,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-0.898,-3.992,3.094,,0.292,E,B,0.44,0.21,0.278,,52.27,HHH,-1.484,0.168804,0.00245633,0.387563 beta-lactamase_156_N274P,beta-lactamase_156_274,TEM-1,beta-lactamase_156,P62593,0.387578,NO,274,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.111618,0.0110418,0.387578 beta-lactamase_2500_L137Q,beta-lactamase_2500_137,TEM-1,beta-lactamase_2500,P62593,0.38761,NO,137,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.03,-4.147,3.117,,,H,A,0.55,-0.38,0.769,,42.31,HHP,-1.58933,0.361275,0.00278599,0.38761 beta-lactamase_156_S233M,beta-lactamase_156_233,TEM-1,beta-lactamase_156,P62593,0.387627,NO,233,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.886,-4.626,2.74,,0.016,E,B,0.27,-1.01,4.111,,77.62,BPO,-1.17267,0.111618,0.00311415,0.387627 kka2_1:2_R239D,kka2_1:2_239,Kka2,kka2_1:2,P00552,0.387634,NO,239,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.949,-2.803,-0.146,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.295029,0.00835326,0.387634 kka2_1:2_H188W,kka2_1:2_188,Kka2,kka2_1:2,P00552,0.387648,NO,188,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-0.913,-5.149,4.236,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.295029,0.00273139,0.387648 kka2_1:8_G213D,kka2_1:8_213,Kka2,kka2_1:8,P00552,0.387775,NO,213,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.596,-3.497,2.901,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.100394,0.00187654,0.387775 kka2_1:8_G213D,kka2_1:8_213,Kka2,kka2_1:8,P00552,0.387775,NO,213,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.596,-3.497,2.901,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.100394,0.00187654,0.387775 beta-lactamase_156_T264P,beta-lactamase_156_264,TEM-1,beta-lactamase_156,P62593,0.387801,NO,264,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.111618,0.0119399,0.387801 kka2_1:2_A191R,kka2_1:2_191,Kka2,kka2_1:2,P00552,0.387854,NO,191,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.831,-3.8,2.969,,,.,b,0.46,-0.94,2.046,,50,AHO,-0.868667,0.295029,0.00338807,0.387854 beta-lactamase_156_G236F,beta-lactamase_156_236,TEM-1,beta-lactamase_156,P62593,0.387879,NO,236,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.784,-4.291,3.507,,0.241,,b,0.29,-0.59,1.883,,64.69,HOO,-1.025,0.111618,0.00162372,0.387879 kka2_1:1_A110T,kka2_1:1_110,Kka2,kka2_1:1,P00552,0.387922,NO,110,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.064,-3.141,1.077,,0.175,H,A,1.04,-1.19,11.755,,71.59,OHA,-1.91867,0.520039,0.00759851,0.387922 kka2_1:2_I115M,kka2_1:2_115,Kka2,kka2_1:2,P00552,0.387964,NO,115,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.606,-2.756,1.15,,0.105,H,A,0.48,-1.18,0.878,,65.53,PHH,-2.205,0.295029,0.00836567,0.387964 kka2_1:1_P98D,kka2_1:1_98,Kka2,kka2_1:1,P00552,0.388036,NO,98,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.526,-2.576,1.05,,0.391,S,B,0.52,-0.65,1.521,,63.26,HOO,-1.19167,0.520039,0.00622754,0.388036 hsp90_M589K,hsp90_589,hsp90,hsp90,P02829,0.388058,NO,589,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-3.858,-2.835,0,4.72723,0.032,H,A,0.84,0.31,,,,PHA,-3.24233,0.368192,0.000222939,0.388058 kka2_1:2_L47N,kka2_1:2_47,Kka2,kka2_1:2,P00552,0.388134,NO,47,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.265,-4.107,2.842,,0.139,E,B,0.55,-0.86,2.369,,63.26,HHH,-1.77933,0.295029,0.00509386,0.388134 kka2_1:1_A110R,kka2_1:1_110,Kka2,kka2_1:1,P00552,0.388174,NO,110,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.064,-3.093,1.029,,0.175,H,A,1.04,-1.19,11.755,,71.59,OHA,-1.91867,0.520039,0.00759851,0.388174 beta-lactamase_625_W208S,beta-lactamase_625_208,TEM-1,beta-lactamase_625,P62593,0.388252,NO,208,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-0.818,-3.836,3.018,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.213352,0.00126609,0.388252 beta-lactamase_625_W208Q,beta-lactamase_625_208,TEM-1,beta-lactamase_625,P62593,0.388297,NO,208,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-0.818,-4.124,3.306,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.213352,0.00126609,0.388297 kka2_1:2_V113H,kka2_1:2_113,Kka2,kka2_1:2,P00552,0.388302,NO,113,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.233,-5.033,3.8,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.295029,0.00650191,0.388302 kka2_1:2_D250I,kka2_1:2_250,Kka2,kka2_1:2,P00552,0.388324,NO,250,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.015,-4.121,3.106,,0.274,.,b,0.75,-0.46,3.796,,51.89,OAP,-1.83933,0.295029,0.0177103,0.388324 hsp90_E590G,hsp90_590,hsp90,hsp90,P02829,0.388379,NO,590,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.818,-2.511,0,4.65049,0.021,H,A,,0.03,,,,HAO,-3.338,0.368192,0.000222939,0.388379 WW_domain_Q186P,WW_domain_186,Yap65,WW_domain,P46937,0.388571,NO,186,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-1.358,-3.432,2.074,4.88854,,,,,,,,,OPB,-1.207,0.153962,0.00161546,0.388571 kka2_1:1_I29N,kka2_1:1_29,Kka2,kka2_1:1,P00552,0.388577,NO,29,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.692,-3.146,1.454,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.520039,0.00619521,0.388577 kka2_1:8_V186N,kka2_1:8_186,Kka2,kka2_1:8,P00552,0.388599,NO,186,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.011,-4.235,3.224,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.100394,0.00409703,0.388599 kka2_1:8_V186N,kka2_1:8_186,Kka2,kka2_1:8,P00552,0.388599,NO,186,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.011,-4.235,3.224,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.100394,0.00409703,0.388599 kka2_1:2_F171S,kka2_1:2_171,Kka2,kka2_1:2,P00552,0.388705,NO,171,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.326,-3.759,2.433,,0.154,H,A,0.58,-0.1,2.645,,63.64,HHH,-1.45433,0.295029,0.00821426,0.388705 kka2_1:4_S104E,kka2_1:4_104,Kka2,kka2_1:4,P00552,0.388707,NO,104,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.436,-2.627,1.191,,0.536,T,A,0.27,-1.11,0.357,,63.64,HPP,-1.91433,0.168804,0.00555207,0.388707 beta-lactamase_2500_V260E,beta-lactamase_2500_260,TEM-1,beta-lactamase_2500,P62593,0.388758,NO,260,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.361275,0.00471757,0.388758 kka2_1:1_R258N,kka2_1:1_258,Kka2,kka2_1:1,P00552,0.388861,NO,258,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.626,-3.818,2.192,,0.316,H,A,1.2,-0.85,7.485,7.485,53.03,HBH,-1.25933,0.520039,0.00983174,0.388861 beta-lactamase_625_T69L,beta-lactamase_625_69,TEM-1,beta-lactamase_625,P62593,0.388885,NO,69,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-0.973,-3.213,2.24,,,G,A,0.22,-1.24,2.716,,93.01,PPH,-1.01833,0.213352,0.00127498,0.388885 kka2_1:4_M197D,kka2_1:4_197,Kka2,kka2_1:4,P00552,0.388943,NO,197,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.707,-4.104,2.397,,0.121,E,B,0.55,-1.19,0.415,,65.53,HHH,-1.847,0.168804,0.00921295,0.388943 kka2_1:4_V113R,kka2_1:4_113,Kka2,kka2_1:4,P00552,0.388977,NO,113,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.233,-4.233,3,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.168804,0.00650191,0.388977 kka2_1:1_A34G,kka2_1:1_34,Kka2,kka2_1:1,P00552,0.388989,NO,34,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.928,-2.969,2.041,,0.417,.,B,0.46,2.29,0.262,,52.27,AHH,-1.747,0.520039,0.00343484,0.388989 kka2_1:2_R147V,kka2_1:2_147,Kka2,kka2_1:2,P00552,0.389022,NO,147,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.123,-3.865,2.742,,0.094,H,A,1.2,0.97,0.425,,64.02,PBH,-1.98267,0.295029,0.00549168,0.389022 kka2_1:2_E262P,kka2_1:2_262,Kka2,kka2_1:2,P00552,0.389057,NO,262,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-0.829,-3.706,2.877,,0.059,G,A,1.04,-0.18,2.383,,42.42,AAH,-0.816,0.295029,0.0191586,0.389057 beta-lactamase_625_S51P,beta-lactamase_625_51,TEM-1,beta-lactamase_625,P62593,0.389088,NO,51,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.526,-3.858,2.332,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.213352,0.00504821,0.389088 beta-lactamase_2500_T263N,beta-lactamase_2500_263,TEM-1,beta-lactamase_2500,P62593,0.389242,NO,263,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.361275,0.0110582,0.389242 beta-lactamase_0_M180C,beta-lactamase_0_180,TEM-1,beta-lactamase_0,P62593,0.389354,NO,180,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-2.795,-4.786,1.991,,0.242,,B,0.55,-0.94,2.892,,77.62,PHO,-1.56433,0.0500837,0.00552048,0.389354 beta-lactamase_156_A230R,beta-lactamase_156_230,TEM-1,beta-lactamase_156,P62593,0.389356,NO,230,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.154,-3.858,2.704,,0.01,E,B,0.46,-1.17,2.179,,50,HHA,-1.079,0.111618,0.00516841,0.389356 kka2_1:2_M148D,kka2_1:2_148,Kka2,kka2_1:2,P00552,0.389419,NO,148,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.847,-4.109,2.262,,0.268,H,A,1.59,0.71,1.439,,64.39,BHA,-1.65467,0.295029,0.00982664,0.389419 kka2_1:4_W24D,kka2_1:4_24,Kka2,kka2_1:4,P00552,0.389493,NO,24,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-1.779,-4.166,2.387,,0.477,E,B,1.51,-0.21,2.666,,56.06,AHH,-2.24467,0.168804,0.00631564,0.389493 beta-lactamase_39_L79D,beta-lactamase_39_79,TEM-1,beta-lactamase_39,P62593,0.3895,NO,79,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.842,-4.141,3.299,,0.007,H,A,0.55,-0.16,0.823,,50.35,HHP,-1.44333,0.0495842,0.000947397,0.3895 kka2_1:8_L232Q,kka2_1:8_232,Kka2,kka2_1:8,P00552,0.389573,NO,232,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.514,-4.349,2.835,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.100394,0.00800103,0.389573 kka2_1:8_L232Q,kka2_1:8_232,Kka2,kka2_1:8,P00552,0.389573,NO,232,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.514,-4.349,2.835,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.100394,0.00800103,0.389573 kka2_1:1_G189Y,kka2_1:1_189,Kka2,kka2_1:1,P00552,0.38959,NO,189,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.596,-4.416,3.82,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.520039,0.00253688,0.38959 kka2_1:1_H139T,kka2_1:1_139,Kka2,kka2_1:1,P00552,0.389681,NO,139,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-2.809,-2.706,-0.103,,0.471,H,A,0.17,0.68,1.153,,63.64,BBB,-2.22,0.520039,0.00734779,0.389681 beta-lactamase_2500_A132E,beta-lactamase_2500_132,TEM-1,beta-lactamase_2500,P62593,0.389685,NO,132,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.9,-3.484,2.584,,,H,A,0.46,-0.93,8.408,,64.69,PHH,-1.138,0.361275,0.000962524,0.389685 beta-lactamase_A235H,beta-lactamase_235,TEM-1,beta-lactamase,P62593,0.389687,NO,235,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.266,-4.769,3.503,4.83024,0.32,E,B,0.52,-0.86,1.344,,50,OHO,-0.89,0.221079,0.00493474,0.389687 kka2_1:2_P12K,kka2_1:2_12,Kka2,kka2_1:2,P00552,0.389801,NO,12,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.853,-3.495,2.642,,,.,B,0.52,1.25,0.261,,48.11,POH,-1.80767,0.295029,0.00500011,0.389801 beta-lactamase_2500_G240S,beta-lactamase_2500_240,TEM-1,beta-lactamase_2500,P62593,0.389811,NO,240,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.537,-2.475,0.938,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.361275,0.00591201,0.389811 kka2_1:8_L174Q,kka2_1:8_174,Kka2,kka2_1:8,P00552,0.389889,NO,174,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.952,-4.163,3.211,,,H,A,1.59,-0.31,1.204,,51.89,BHB,-2.08533,0.100394,0.00438501,0.389889 kka2_1:8_L174Q,kka2_1:8_174,Kka2,kka2_1:8,P00552,0.389889,NO,174,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.952,-4.163,3.211,,,H,A,1.59,-0.31,1.204,,51.89,BHB,-2.08533,0.100394,0.00438501,0.389889 kka2_1:1_I115S,kka2_1:1_115,Kka2,kka2_1:1,P00552,0.390006,NO,115,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.606,-2.994,1.388,,0.105,H,A,0.48,-1.18,0.878,,65.53,PHH,-2.205,0.520039,0.00836567,0.390006 beta-lactamase_625_A132T,beta-lactamase_625_132,TEM-1,beta-lactamase_625,P62593,0.390033,NO,132,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.9,-3.22,2.32,,,H,A,0.46,-0.93,0.316,,64.69,PHH,-1.138,0.213352,0.000962524,0.390033 beta-lactamase_2500_A215Y,beta-lactamase_2500_215,TEM-1,beta-lactamase_2500,P62593,0.390037,NO,215,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.503,-4.339,2.836,,,,a,0.46,-0.93,3.516,,74.48,HHO,-1.42633,0.361275,0.00544007,0.390037 beta-lactamase_D212W,beta-lactamase_212,TEM-1,beta-lactamase,P62593,0.39014,NO,212,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.624,-5.54,3.916,4.9705,0.037,,b,1.3,-0.58,12.482,,74.48,HAB,-1.77667,0.221079,0.00644302,0.39014 kka2_1:1_G21K,kka2_1:1_21,Kka2,kka2_1:1,P00552,0.390149,NO,21,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.368,-3.662,2.294,,0.586,T,l,0.29,-0.75,10.291,10.291,71.59,HOH,-2.10167,0.520039,0.00709648,0.390149 beta-lactamase_156_A246N,beta-lactamase_156_246,TEM-1,beta-lactamase_156,P62593,0.390285,NO,246,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.121,-4.23,2.109,,0.01,E,B,0.46,-1.01,1.959,,73.78,HHH,-1.55633,0.111618,0.00569458,0.390285 beta-lactamase_156_N130M,beta-lactamase_156_130,TEM-1,beta-lactamase_156,P62593,0.3903,NO,130,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-0.798,-4.705,3.907,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.111618,0.000683376,0.3903 beta-lactamase_2500_T158V,beta-lactamase_2500_158,TEM-1,beta-lactamase_2500,P62593,0.390322,NO,158,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.116,-3.299,2.183,,0.036,,B,0.22,-0.85,1.344,,69.58,HPB,-1.269,0.361275,0.00341825,0.390322 kka2_1:4_G88N,kka2_1:4_88,Kka2,kka2_1:4,P00552,0.390367,NO,88,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.689,-2.869,1.18,,0.54,S,l,0.29,1.51,7.899,,65.53,HOB,-1.718,0.168804,0.00685559,0.390367 kka2_1:8_R211V,kka2_1:8_211,Kka2,kka2_1:8,P00552,0.390421,NO,211,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-0.899,-3.805,2.906,,0.12,T,a,0.16,-0.39,0.615,,49.62,OBH,-0.966,0.100394,0.00204888,0.390421 kka2_1:8_R211V,kka2_1:8_211,Kka2,kka2_1:8,P00552,0.390421,NO,211,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-0.899,-3.805,2.906,,0.12,T,a,0.16,-0.39,0.615,,49.62,OBH,-0.966,0.100394,0.00204888,0.390421 beta-lactamase_625_T178Q,beta-lactamase_625_178,TEM-1,beta-lactamase_625,P62593,0.390486,NO,178,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-0.791,-3.899,3.108,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.213352,0.000684366,0.390486 kka2_1:1_A56C,kka2_1:1_56,Kka2,kka2_1:1,P00552,0.390549,NO,56,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.083,-5.094,3.011,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.520039,0.00717715,0.390549 beta-lactamase_Y95S,beta-lactamase_95,TEM-1,beta-lactamase,P62593,0.390552,NO,95,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-1.715,-3.776,2.061,5.67068,0.122,,b,0.96,-0.37,2.341,,77.62,BHP,-2.16167,0.221079,0.00479449,0.390552 kka2_1:4_V113D,kka2_1:4_113,Kka2,kka2_1:4,P00552,0.390554,NO,113,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.233,-4.075,2.842,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.168804,0.00650191,0.390554 beta-lactamase_156_L137D,beta-lactamase_156_137,TEM-1,beta-lactamase_156,P62593,0.390681,NO,137,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.03,-4.128,3.098,,,H,A,0.55,-0.38,0.674,,42.31,HHP,-1.58933,0.111618,0.00278599,0.390681 beta-lactamase_2500_F228N,beta-lactamase_2500_228,TEM-1,beta-lactamase_2500,P62593,0.390683,NO,228,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-2.342,-3.038,0.696,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.361275,0.0046669,0.390683 kka2_1:2_H135L,kka2_1:2_135,Kka2,kka2_1:2,P00552,0.390719,NO,135,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-1.331,-2.788,1.457,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.295029,0.00532566,0.390719 kka2_1:2_H135V,kka2_1:2_135,Kka2,kka2_1:2,P00552,0.390719,NO,135,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-1.331,-3.678,2.347,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.295029,0.00532566,0.390719 kka2_1:2_R217H,kka2_1:2_217,Kka2,kka2_1:2,P00552,0.390733,NO,217,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.158,-4.518,3.36,,0.252,T,A,1.2,-0.59,0.381,,52.27,ABH,-1.127,0.295029,0.0047191,0.390733 kka2_1:1_E161P,kka2_1:1_161,Kka2,kka2_1:1,P00552,0.390745,NO,161,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.581,-2.997,1.416,,0.829,G,A,1.04,2.24,1.612,,92.05,AAB,-1.861,0.520039,0.00760103,0.390745 kka2_1:4_D90Y,kka2_1:4_90,Kka2,kka2_1:4,P00552,0.390781,NO,90,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.459,-3.217,0.758,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.168804,0.00583842,0.390781 beta-lactamase_2500_L49R,beta-lactamase_2500_49,TEM-1,beta-lactamase_2500,P62593,0.39091,NO,49,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.897,-3.032,1.135,,0.131,T,A,0.55,0.04,6.681,,64.69,AHP,-1.99233,0.361275,0.00401477,0.39091 kka2_1:1_S204H,kka2_1:1_204,Kka2,kka2_1:1,P00552,0.39093,NO,204,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.353,-4.723,3.37,,0.144,E,A,0.27,-1.2,3.022,,65.53,HPO,-0.953333,0.520039,0.00881794,0.39093 kka2_1:1_W15T,kka2_1:1_15,Kka2,kka2_1:1,P00552,0.39093,NO,15,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-1.392,-3.666,2.274,,0.01,G,A,0.47,0.15,20.149,20.149,52.27,HHH,-2.10533,0.520039,0.00585505,0.39093 kka2_1:1_E231D,kka2_1:1_231,Kka2,kka2_1:1,P00552,0.39097,NO,231,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.002,-2.09,0.088,,0.503,H,A,1.04,-0.23,25.629,25.629,63.26,AAH,-2.06267,0.520039,0.00732383,0.39097 kka2_1:8_A119D,kka2_1:8_119,Kka2,kka2_1:8,P00552,0.391046,NO,119,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.073,-3.713,2.64,,0.019,H,A,0.46,-0.57,1.511,,71.59,AHH,-2.34,0.100394,0.00441074,0.391046 kka2_1:8_A119D,kka2_1:8_119,Kka2,kka2_1:8,P00552,0.391046,NO,119,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.073,-3.713,2.64,,0.019,H,A,0.46,-0.57,1.511,,71.59,AHH,-2.34,0.100394,0.00441074,0.391046 kka2_1:1_K175Q,kka2_1:1_175,Kka2,kka2_1:1,P00552,0.391061,NO,175,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-2.897,-2.736,-0.161,,0.579,H,A,1.3,0.51,9.33,9.33,71.59,HBH,-1.82333,0.520039,0.00693093,0.391061 kka2_1:8_F206E,kka2_1:8_206,Kka2,kka2_1:8,P00552,0.391065,NO,206,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.349,-3.931,2.582,,0.006,E,B,1.62,-1.21,1.052,,63.64,OHH,-1.04,0.100394,0.00936868,0.391065 kka2_1:8_F206E,kka2_1:8_206,Kka2,kka2_1:8,P00552,0.391065,NO,206,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.349,-3.931,2.582,,0.006,E,B,1.62,-1.21,1.052,,63.64,OHH,-1.04,0.100394,0.00936868,0.391065 kka2_1:4_P132D,kka2_1:4_132,Kka2,kka2_1:4,P00552,0.391077,NO,132,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.775,-3.495,2.72,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.168804,0.0018489,0.391077 beta-lactamase_2500_I244A,beta-lactamase_2500_244,TEM-1,beta-lactamase_2500,P62593,0.391097,NO,244,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.555,-3.008,1.453,,,E,B,0.48,-0.84,1.683,,77.62,OHH,-1.385,0.361275,0.00605379,0.391097 kka2_1:8_C192H,kka2_1:8_192,Kka2,kka2_1:8,P00552,0.391151,NO,192,C,H,CH,Special,PositiveCharge,5.07,7.59,2.52,174,121,155,34,108.5,153.2,44.7,-1.067,-4.779,3.712,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.100394,0.00485428,0.391151 kka2_1:8_C192H,kka2_1:8_192,Kka2,kka2_1:8,P00552,0.391151,NO,192,C,H,CH,Special,PositiveCharge,5.07,7.59,2.52,174,121,155,34,108.5,153.2,44.7,-1.067,-4.779,3.712,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.100394,0.00485428,0.391151 kka2_1:4_F203N,kka2_1:4_203,Kka2,kka2_1:4,P00552,0.391157,NO,203,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-0.911,-4.185,3.274,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.168804,0.00318738,0.391157 kka2_1:1_V214K,kka2_1:1_214,Kka2,kka2_1:1,P00552,0.39122,NO,214,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.261,-3.816,2.555,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.520039,0.00692782,0.39122 beta-lactamase_625_T27G,beta-lactamase_625_27,TEM-1,beta-lactamase_625,P62593,0.391234,NO,27,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.905,-3.36,1.455,,0.007,H,A,0.22,-0.37,3.72,,93.01,APH,-1.97933,0.213352,0.00306559,0.391234 WW_domain_R203H,WW_domain_203,Yap65,WW_domain,P46937,0.391271,NO,203,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.539,-4.252,2.713,5.41321,,,,,,1.9,,70.04,OBO,-1.4695,0.153962,0.00172433,0.391271 beta-lactamase_625_I258Y,beta-lactamase_625_258,TEM-1,beta-lactamase_625,P62593,0.391291,NO,258,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.213352,0.007931,0.391291 PSD95pdz3_H372C,PSD95pdz3_372,PSD95pdz3,PSD95pdz3,P31016,0.391292,NO,372,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-1.627,-4.769,3.142,5.5607,,,,,17.008,,,,PBA,-1.63033,0.0758425,0.00040301,0.391292 kka2_1:1_G10W,kka2_1:1_10,Kka2,kka2_1:1,P00552,0.391334,NO,10,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.921,-5.359,3.438,,,,,,,1.862,,71.59,HOP,-2.10733,0.520039,0.00289233,0.391334 kka2_1:1_S251C,kka2_1:1_251,Kka2,kka2_1:1,P00552,0.391353,NO,251,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.636,-5.186,2.55,,0.712,H,A,0.27,-0.25,1.356,,71.59,APP,-2.09367,0.520039,0.0138916,0.391353 kka2_1:1_C209P,kka2_1:1_209,Kka2,kka2_1:1,P00552,0.391357,NO,209,C,P,CP,Special,Special,5.07,6.3,1.23,169,121,115,-6,108.5,112.7,4.2,-0.906,-4.156,3.25,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.520039,0.00260862,0.391357 kka2_1:8_R202P,kka2_1:8_202,Kka2,kka2_1:8,P00552,0.391361,NO,202,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.761,-4.079,2.318,,0.607,E,B,1.2,0.48,1.409,,52.27,OBH,-1.41067,0.100394,0.00696498,0.391361 kka2_1:8_R202P,kka2_1:8_202,Kka2,kka2_1:8,P00552,0.391361,NO,202,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.761,-4.079,2.318,,0.607,E,B,1.2,0.48,1.409,,52.27,OBH,-1.41067,0.100394,0.00696498,0.391361 beta-lactamase_625_I45N,beta-lactamase_625_45,TEM-1,beta-lactamase_625,P62593,0.391386,NO,45,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-2.421,-3.135,0.714,,,E,B,0.48,-0.3,3.642,,77.62,HHA,-2.30267,0.213352,0.00452842,0.391386 kka2_1:1_W236S,kka2_1:1_236,Kka2,kka2_1:1,P00552,0.391405,NO,236,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-1.363,-3.736,2.373,,0.303,H,A,1.51,-0.76,12.263,12.263,48.48,AHH,-1.81267,0.520039,0.0088796,0.391405 kka2_1:2_C209K,kka2_1:2_209,Kka2,kka2_1:2,P00552,0.391426,NO,209,C,K,CK,Special,PositiveCharge,5.07,9.74,4.67,202,121,146,25,108.5,168.6,60.1,-0.906,-3.933,3.027,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.295029,0.00260862,0.391426 kka2_1:4_H162Y,kka2_1:4_162,Kka2,kka2_1:4,P00552,0.391549,NO,162,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-2.319,-3.937,1.618,,0.071,G,A,0.17,1.01,3.187,,64.39,ABP,-2.02067,0.168804,0.00616145,0.391549 kka2_1:4_E262N,kka2_1:4_262,Kka2,kka2_1:4,P00552,0.391626,NO,262,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-0.829,-3.499,2.67,,0.059,G,A,1.04,-0.18,2.383,,42.42,AAH,-0.816,0.168804,0.0191586,0.391626 kka2_1:4_L212Q,kka2_1:4_212,Kka2,kka2_1:4,P00552,0.391631,NO,212,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.904,-4.175,3.271,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.168804,0.0031426,0.391631 kka2_1:4_F256Q,kka2_1:4_256,Kka2,kka2_1:4,P00552,0.391645,NO,256,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.49,-4.227,2.737,,,H,A,0.58,-0.78,1.653,,53.03,HHH,-1.423,0.168804,0.0132841,0.391645 kka2_1:8_D208W,kka2_1:8_208,Kka2,kka2_1:8,P00552,0.391664,NO,208,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.708,-5.576,4.868,,0.36,,l,0.29,-1.01,,,,HAO,-0.929667,0.100394,0.00212588,0.391664 kka2_1:8_D208W,kka2_1:8_208,Kka2,kka2_1:8,P00552,0.391664,NO,208,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.708,-5.576,4.868,,0.36,,l,0.29,-1.01,,,,HAO,-0.929667,0.100394,0.00212588,0.391664 kka2_1:1_L39G,kka2_1:1_39,Kka2,kka2_1:1,P00552,0.391666,NO,39,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.223,-2.832,1.609,,,E,B,0.55,-1.21,0.925,,71.59,BHP,-1.69167,0.520039,0.00493618,0.391666 beta-lactamase_2500_E62R,beta-lactamase_2500_62,TEM-1,beta-lactamase_2500,P62593,0.39168,NO,62,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.193,-3.663,2.47,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.361275,0.00264802,0.39168 kka2_1:1_D227S,kka2_1:1_227,Kka2,kka2_1:1,P00552,0.391724,NO,227,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.758,-1.053,-0.705,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.520039,0.00745029,0.391724 kka2_1:4_L174I,kka2_1:4_174,Kka2,kka2_1:4,P00552,0.391785,NO,174,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.952,-3.013,2.061,,,H,A,0.55,-0.31,1.339,,51.89,BHB,-2.08533,0.168804,0.00438501,0.391785 kka2_1:4_R217H,kka2_1:4_217,Kka2,kka2_1:4,P00552,0.391887,NO,217,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.158,-4.518,3.36,,0.252,T,A,1.2,-0.59,2.074,,52.27,ABH,-1.127,0.168804,0.0047191,0.391887 kka2_1:8_V186Y,kka2_1:8_186,Kka2,kka2_1:8,P00552,0.391902,NO,186,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.011,-3.942,2.931,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.100394,0.00409703,0.391902 kka2_1:8_V186Y,kka2_1:8_186,Kka2,kka2_1:8,P00552,0.391902,NO,186,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.011,-3.942,2.931,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.100394,0.00409703,0.391902 beta-lactamase_156_G249D,beta-lactamase_156_249,TEM-1,beta-lactamase_156,P62593,0.391906,NO,249,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.111618,0.00220169,0.391906 kka2_1:1_I2G,kka2_1:1_2,Kka2,kka2_1:1,P00552,0.391906,NO,2,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.787,-3.438,1.651,,,,,,,2.329,,71.59,HHA,-1.92433,0.520039,0.00246644,0.391906 kka2_1:2_L241Y,kka2_1:2_241,Kka2,kka2_1:2,P00552,0.391906,NO,241,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.158,-3.64,2.482,,0.08,H,A,0.55,-0.82,1.598,,63.26,HHH,-1.58533,0.295029,0.0117299,0.391906 kka2_1:4_A215V,kka2_1:4_215,Kka2,kka2_1:4,P00552,0.391936,NO,215,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.968,-3.282,2.314,,0.039,E,B,0.46,-0.59,0.754,,50.38,HHA,-1.00467,0.168804,0.00529129,0.391936 kka2_1:1_L158N,kka2_1:1_158,Kka2,kka2_1:1,P00552,0.391958,NO,158,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.947,-4.203,2.256,,0.095,.,B,0.55,0.77,7.588,,63.64,AHA,-1.25333,0.520039,0.00529068,0.391958 kka2_1:1_L158Y,kka2_1:1_158,Kka2,kka2_1:1,P00552,0.391958,NO,158,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.947,-3.398,1.451,,0.095,.,B,0.55,0.77,7.588,,63.64,AHA,-1.25333,0.520039,0.00529068,0.391958 kka2_1:1_L81N,kka2_1:1_81,Kka2,kka2_1:1,P00552,0.391986,NO,81,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.427,-4.237,2.81,,0.46,E,A,0.55,-0.14,0.374,,63.64,HHA,-1.50567,0.520039,0.00805839,0.391986 beta-lactamase_156_R59V,beta-lactamase_156_59,TEM-1,beta-lactamase_156,P62593,0.39204,NO,59,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.345,-3.76,2.415,,0.329,S,L,1.2,-0.09,2.995,,73.08,HBO,-2.24267,0.111618,0.00318082,0.39204 kka2_1:4_D118P,kka2_1:4_118,Kka2,kka2_1:4,P00552,0.39205,NO,118,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.07,-4.037,1.967,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.168804,0.0067852,0.39205 kka2_1:1_G164K,kka2_1:1_164,Kka2,kka2_1:1,P00552,0.392061,NO,164,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.869,-3.652,2.783,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.520039,0.00442091,0.392061 kka2_1:1_D216N,kka2_1:1_216,Kka2,kka2_1:1,P00552,0.392102,NO,216,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.785,-3.274,2.489,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.520039,0.00229969,0.392102 kka2_1:1_W236H,kka2_1:1_236,Kka2,kka2_1:1,P00552,0.392144,NO,236,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-1.363,-4.78,3.417,,0.303,H,A,1.51,-0.76,12.263,12.263,48.48,AHH,-1.81267,0.520039,0.0088796,0.392144 kka2_1:1_D156S,kka2_1:1_156,Kka2,kka2_1:1,P00552,0.392157,NO,156,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.696,-2.049,0.353,,0.884,T,A,0.75,1.87,1.044,,65.53,PAA,-1.765,0.520039,0.00926998,0.392157 kka2_1:4_A172W,kka2_1:4_172,Kka2,kka2_1:4,P00552,0.392169,NO,172,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.757,-5.588,3.831,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.168804,0.0079265,0.392169 kka2_1:8_W69N,kka2_1:8_69,Kka2,kka2_1:8,P00552,0.392199,NO,69,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-0.859,-4.344,3.485,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.100394,0.0012874,0.392199 kka2_1:8_W69N,kka2_1:8_69,Kka2,kka2_1:8,P00552,0.392199,NO,69,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-0.859,-4.344,3.485,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.100394,0.0012874,0.392199 kka2_1:4_D220S,kka2_1:4_220,Kka2,kka2_1:4,P00552,0.392315,NO,220,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.787,-3.25,2.463,,,H,A,0.75,-1.14,1.237,,46.59,PAH,-1.152,0.168804,0.00158066,0.392315 kka2_1:2_H188Y,kka2_1:2_188,Kka2,kka2_1:2,P00552,0.392491,NO,188,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-0.913,-3.365,2.452,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.295029,0.00273139,0.392491 beta-lactamase_A245I,beta-lactamase_245,TEM-1,beta-lactamase,P62593,0.392499,NO,245,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.068,-3.611,2.543,4.78972,,E,B,0.17,-0.92,0.831,,64.69,HHH,-1.58133,0.221079,0.00391032,0.392499 kka2_1:4_V36E,kka2_1:4_36,Kka2,kka2_1:4,P00552,0.392513,NO,36,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-0.898,-3.776,2.878,,0.292,E,B,0.44,0.21,0.278,,52.27,HHH,-1.484,0.168804,0.00245633,0.392513 kka2_1:8_V185D,kka2_1:8_185,Kka2,kka2_1:8,P00552,0.392513,NO,185,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.045,-4.011,2.966,,0.058,E,B,1.48,-0.49,1.234,,46.97,HHH,-1.184,0.100394,0.00367031,0.392513 kka2_1:8_V185D,kka2_1:8_185,Kka2,kka2_1:8,P00552,0.392513,NO,185,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.045,-4.011,2.966,,0.058,E,B,1.48,-0.49,1.234,,46.97,HHH,-1.184,0.100394,0.00367031,0.392513 Pab1_S154L,Pab1_154,Pab1,Pab1,P04147,0.392523,NO,154,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.146,-3.175,2.029,,0.208,E,B,0.1,-0.75,,,,HPP,-1.408,0.175299,0.000319331,0.392523 beta-lactamase_2500_L38R,beta-lactamase_2500_38,TEM-1,beta-lactamase_2500,P62593,0.392557,NO,38,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.343,-4.054,2.711,,0.088,H,A,0.55,0.2,2.71,,64.34,PHO,-1.78033,0.361275,0.00373244,0.392557 kka2_1:1_H162Y,kka2_1:1_162,Kka2,kka2_1:1,P00552,0.392634,NO,162,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-2.319,-3.937,1.618,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.520039,0.00616145,0.392634 beta-lactamase_2500_R162A,beta-lactamase_2500_162,TEM-1,beta-lactamase_2500,P62593,0.39269,NO,162,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.016,-3.127,2.111,,0.124,S,B,1.2,-0.37,6.199,,64.69,ABH,-1.25,0.361275,0.000561334,0.39269 kka2_1:2_L260R,kka2_1:2_260,Kka2,kka2_1:2,P00552,0.392701,NO,260,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.741,-3.961,3.22,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.295029,0.0233782,0.392701 Pab1_G150W,Pab1_150,Pab1,Pab1,P04147,0.392783,NO,150,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.809,-4.915,4.106,,0.287,S,b,0.23,0.53,,,,HOA,-1.45233,0.175299,0.000323835,0.392783 kka2_1:1_L165T,kka2_1:1_165,Kka2,kka2_1:1,P00552,0.39297,NO,165,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-2.453,-3.066,0.613,,0.299,,B,1.59,1.12,2.47,,64.39,OHH,-1.90967,0.520039,0.00801161,0.39297 beta-lactamase_2500_D231E,beta-lactamase_2500_231,TEM-1,beta-lactamase_2500,P62593,0.392982,NO,231,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.816,-2.232,1.416,,,E,B,0.75,-1.06,0.319,,65.38,HAB,-0.994,0.361275,0.00107395,0.392982 gb1_L233D,gb1_233,gb1,gb1,P06654,0.393001,NO,233,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-2.678,-3.476,0.798,,,,,,,0.822,,45.54,HHP,-2.30267,0.177985,0.00266958,0.393001 gb1_V265H,gb1_265,gb1,gb1,P06654,0.393001,NO,265,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.843,-4.624,2.781,,,,,,,0.402,,11.83,OHA,-1.64567,0.177985,0.00360613,0.393001 beta-lactamase_625_W208T,beta-lactamase_625_208,TEM-1,beta-lactamase_625,P62593,0.393012,NO,208,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-0.818,-3.646,2.828,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.213352,0.00126609,0.393012 beta-lactamase_625_R59L,beta-lactamase_625_59,TEM-1,beta-lactamase_625,P62593,0.393086,NO,59,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.345,-3.484,2.139,,0.329,S,L,1.2,-0.09,2.995,,73.08,HBO,-2.24267,0.213352,0.00318082,0.393086 kka2_1:4_G210L,kka2_1:4_210,Kka2,kka2_1:4,P00552,0.393103,NO,210,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.095,-3.634,2.539,,0.103,T,A,0.29,-0.62,0.271,,50,OOB,-0.966667,0.168804,0.00598378,0.393103 kka2_1:4_H135V,kka2_1:4_135,Kka2,kka2_1:4,P00552,0.393108,NO,135,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-1.331,-3.678,2.347,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.168804,0.00532566,0.393108 kka2_1:1_L174G,kka2_1:1_174,Kka2,kka2_1:1,P00552,0.393118,NO,174,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.952,-3.755,2.803,,,H,A,0.55,-0.31,13.276,13.276,51.89,BHB,-2.08533,0.520039,0.00438501,0.393118 kka2_1:4_L241Y,kka2_1:4_241,Kka2,kka2_1:4,P00552,0.393139,NO,241,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.158,-3.64,2.482,,0.08,H,A,0.55,-0.82,1.598,,63.26,HHH,-1.58533,0.168804,0.0117299,0.393139 kka2_1:2_L170R,kka2_1:2_170,Kka2,kka2_1:2,P00552,0.393171,NO,170,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.28,-4.103,2.823,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.295029,0.00730791,0.393171 kka2_1:2_V113D,kka2_1:2_113,Kka2,kka2_1:2,P00552,0.393183,NO,113,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.233,-4.075,2.842,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.295029,0.00650191,0.393183 beta-lactamase_625_P65Y,beta-lactamase_625_65,TEM-1,beta-lactamase_625,P62593,0.393203,NO,65,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.894,-4.31,3.416,,0.098,E,B,0.52,-0.62,0.3,,40.56,HOH,-1.03233,0.213352,0.00152776,0.393203 kka2_1:2_D216N,kka2_1:2_216,Kka2,kka2_1:2,P00552,0.393242,NO,216,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.785,-3.274,2.489,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.295029,0.00229969,0.393242 kka2_1:2_R253N,kka2_1:2_253,Kka2,kka2_1:2,P00552,0.393243,NO,253,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.356,-3.661,2.305,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.295029,0.0144195,0.393243 kka2_1:8_C131L,kka2_1:8_131,Kka2,kka2_1:8,P00552,0.393348,NO,131,C,L,CL,Special,Hydrophobic,5.07,9.7088,4.6388,198,121,131,10,108.5,166.7,58.2,-0.831,-3.161,2.33,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.100394,0.00170814,0.393348 kka2_1:8_C131L,kka2_1:8_131,Kka2,kka2_1:8,P00552,0.393348,NO,131,C,L,CL,Special,Hydrophobic,5.07,9.7088,4.6388,198,121,131,10,108.5,166.7,58.2,-0.831,-3.161,2.33,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.100394,0.00170814,0.393348 kka2_1:1_E231L,kka2_1:1_231,Kka2,kka2_1:1,P00552,0.393349,NO,231,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.002,-3.642,1.64,,0.503,H,A,1.04,-0.23,25.629,25.629,63.26,AAH,-2.06267,0.520039,0.00732383,0.393349 beta-lactamase_0_R159I,beta-lactamase_0_159,TEM-1,beta-lactamase_0,P62593,0.393356,NO,159,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-0.94,-4.036,3.096,,0.316,,B,1.2,-0.55,1.426,,64.34,PBH,-1.011,0.0500837,0.00108472,0.393356 kka2_1:1_V80A,kka2_1:1_80,Kka2,kka2_1:1,P00552,0.393383,NO,80,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.144,-2.287,1.143,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.520039,0.00488211,0.393383 kka2_1:8_Y244D,kka2_1:8_244,Kka2,kka2_1:8,P00552,0.393452,NO,244,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-0.775,-3.947,3.172,,0.066,H,A,1.25,-0.64,,,,HHO,-1.41267,0.100394,0.00453187,0.393452 kka2_1:8_Y244D,kka2_1:8_244,Kka2,kka2_1:8,P00552,0.393452,NO,244,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-0.775,-3.947,3.172,,0.066,H,A,1.25,-0.64,,,,HHO,-1.41267,0.100394,0.00453187,0.393452 kka2_1:4_L184S,kka2_1:4_184,Kka2,kka2_1:4,P00552,0.393526,NO,184,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.496,-3.717,2.221,,0.489,E,B,1.59,-0.06,4.495,,63.26,AHH,-1.24833,0.168804,0.00518742,0.393526 kka2_1:8_D90F,kka2_1:8_90,Kka2,kka2_1:8,P00552,0.393556,NO,90,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.459,-3.305,0.846,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.100394,0.00583842,0.393556 kka2_1:8_D90F,kka2_1:8_90,Kka2,kka2_1:8,P00552,0.393556,NO,90,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.459,-3.305,0.846,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.100394,0.00583842,0.393556 kka2_1:4_R217S,kka2_1:4_217,Kka2,kka2_1:4,P00552,0.393609,NO,217,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.158,-3.548,2.39,,0.252,T,A,1.2,-0.59,2.074,,52.27,ABH,-1.127,0.168804,0.0047191,0.393609 kka2_1:2_P194V,kka2_1:2_194,Kka2,kka2_1:2,P00552,0.393623,NO,194,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.846,-3.62,2.774,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.295029,0.00314194,0.393623 beta-lactamase_I275W,beta-lactamase_275,TEM-1,beta-lactamase,P62593,0.393759,NO,275,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.397,-5.252,3.855,5.3999,0.015,H,A,1,-0.52,0.836,,62.59,PHH,-1.541,0.221079,0.0141984,0.393759 beta-lactamase_Q203C,beta-lactamase_203,TEM-1,beta-lactamase,P62593,0.393759,NO,203,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.168,-5.086,2.918,5.65296,0.47,H,A,0.12,-0.38,1.66,,65.38,BPP,-1.614,0.221079,0.00631514,0.393759 kka2_1:1_L19T,kka2_1:1_19,Kka2,kka2_1:1,P00552,0.393769,NO,19,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.254,-3.645,2.391,,0.08,T,A,0.55,-0.26,17.165,17.165,65.53,BHH,-2.221,0.520039,0.00620703,0.393769 kka2_1:2_F37G,kka2_1:2_37,Kka2,kka2_1:2,P00552,0.393807,NO,37,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.427,-3.622,2.195,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.295029,0.00586193,0.393807 beta-lactamase_2500_G114P,beta-lactamase_2500_114,TEM-1,beta-lactamase_2500,P62593,0.393833,NO,114,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.094,-3.918,2.824,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.361275,0.00224919,0.393833 beta-lactamase_625_L74N,beta-lactamase_625_74,TEM-1,beta-lactamase_625,P62593,0.393885,NO,74,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.296,-4.114,2.818,,,H,A,0.55,-0.91,0.895,,50,HHO,-1.34933,0.213352,0.00493255,0.393885 kka2_1:4_T187N,kka2_1:4_187,Kka2,kka2_1:4,P00552,0.393902,NO,187,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.273,-3.75,2.477,,0.007,E,B,0.22,-0.85,2.73,,52.27,HPB,-1.06567,0.168804,0.00693073,0.393902 kka2_1:1_Q4D,kka2_1:1_4,Kka2,kka2_1:1,P00552,0.393906,NO,4,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.361,-3.094,0.733,,,,,,,5.615,,71.59,APA,-1.95533,0.520039,0.00239179,0.393906 kka2_1:1_R140F,kka2_1:1_140,Kka2,kka2_1:1,P00552,0.393948,NO,140,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.351,-4.407,3.056,,0.12,H,A,1.2,0.2,11.345,11.345,53.03,BBH,-1.885,0.520039,0.00430167,0.393948 kka2_1:8_A222R,kka2_1:8_222,Kka2,kka2_1:8,P00552,0.394008,NO,222,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.725,-3.736,3.011,,,H,A,1.04,-1.21,,,,HHH,-1.10833,0.100394,0.00207657,0.394008 kka2_1:8_A222R,kka2_1:8_222,Kka2,kka2_1:8,P00552,0.394008,NO,222,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.725,-3.736,3.011,,,H,A,1.04,-1.21,,,,HHH,-1.10833,0.100394,0.00207657,0.394008 kka2_1:1_W236Q,kka2_1:1_236,Kka2,kka2_1:1,P00552,0.394052,NO,236,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-1.363,-4.284,2.921,,0.303,H,A,1.51,-0.76,12.263,12.263,48.48,AHH,-1.81267,0.520039,0.0088796,0.394052 beta-lactamase_39_L205P,beta-lactamase_39_205,TEM-1,beta-lactamase_39,P62593,0.394083,NO,205,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.922,-4.159,3.237,,,H,A,0.55,-0.46,0.846,,42.31,PHH,-1.57767,0.0495842,0.00255802,0.394083 beta-lactamase_2500_L197G,beta-lactamase_2500_197,TEM-1,beta-lactamase_2500,P62593,0.394218,NO,197,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.853,-3.681,2.828,,0.007,S,B,0.55,0.33,2.421,,60.14,HHP,-1.833,0.361275,0.00144602,0.394218 kka2_1:1_A166M,kka2_1:1_166,Kka2,kka2_1:1,P00552,0.394246,NO,166,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.407,-4.784,2.377,,0.534,.,B,0.46,1.03,1.147,,71.59,HHO,-2.421,0.520039,0.00799912,0.394246 kka2_1:4_L152N,kka2_1:4_152,Kka2,kka2_1:4,P00552,0.394254,NO,152,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.521,-4.061,2.54,,0.547,,A,1.59,1.36,2.318,,63.64,OHH,-1.162,0.168804,0.00674868,0.394254 kka2_1:8_C77W,kka2_1:8_77,Kka2,kka2_1:8,P00552,0.394285,NO,77,C,W,CW,Special,Hydrophobic,5.07,5.89,0.82,215,121,204,83,108.5,227.8,119.3,-1.477,-5.341,3.864,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.100394,0.00441216,0.394285 kka2_1:8_C77W,kka2_1:8_77,Kka2,kka2_1:8,P00552,0.394285,NO,77,C,W,CW,Special,Hydrophobic,5.07,5.89,0.82,215,121,204,83,108.5,227.8,119.3,-1.477,-5.341,3.864,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.100394,0.00441216,0.394285 kka2_1:1_L7W,kka2_1:1_7,Kka2,kka2_1:1,P00552,0.394302,NO,7,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.926,-5.046,3.12,,,,,,,18.934,18.934,71.59,OHB,-2.12333,0.520039,0.00269456,0.394302 E1_Ubiquitin_R72L,E1_Ubiquitin_72,Uba1,E1_Ubiquitin,P0CG63,0.394341,NO,72,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.184,-3.175,1.991,,0.077,,B,0.16,-0.1,,,,HBH,-1.08733,0.18783,0.00129853,0.394341 kka2_1:1_I141D,kka2_1:1_141,Kka2,kka2_1:1,P00552,0.394344,NO,141,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.495,-4.166,2.671,,0.068,H,A,0.48,-0.01,7.546,7.546,92.05,BHA,-1.689,0.520039,0.00744745,0.394344 beta-lactamase_G279E,beta-lactamase_279,TEM-1,beta-lactamase,P62593,0.394474,NO,279,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.038,-3.588,2.55,4.53882,,H,A,0.46,-0.97,3.066,,62.59,HOH,-1.36467,0.221079,0.0192826,0.394474 beta-lactamase_156_I229K,beta-lactamase_156_229,TEM-1,beta-lactamase_156,P62593,0.394477,NO,229,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.267,-3.862,2.595,,0.083,E,B,0.48,-0.76,1.114,,50,HHH,-1.58767,0.111618,0.00477249,0.394477 kka2_1:8_G189D,kka2_1:8_189,Kka2,kka2_1:8,P00552,0.394492,NO,189,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.596,-3.497,2.901,,0.034,S,l,0.75,-0.99,,,,BOA,-0.739,0.100394,0.00253688,0.394492 kka2_1:8_G189D,kka2_1:8_189,Kka2,kka2_1:8,P00552,0.394492,NO,189,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.596,-3.497,2.901,,0.034,S,l,0.75,-0.99,,,,BOA,-0.739,0.100394,0.00253688,0.394492 kka2_1:8_G233K,kka2_1:8_233,Kka2,kka2_1:8,P00552,0.394492,NO,233,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.748,-3.71,2.962,,0.172,,b,0.75,-0.27,1.134,,49.24,HOO,-1.72067,0.100394,0.00232366,0.394492 kka2_1:8_G233K,kka2_1:8_233,Kka2,kka2_1:8,P00552,0.394492,NO,233,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.748,-3.71,2.962,,0.172,,b,0.75,-0.27,1.134,,49.24,HOO,-1.72067,0.100394,0.00232366,0.394492 kka2_1:2_F133L,kka2_1:2_133,Kka2,kka2_1:2,P00552,0.39451,NO,133,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-0.871,-2.98,2.109,,0.178,.,B,0.58,0.43,1.999,,42.42,OHA,-0.871667,0.295029,0.00182168,0.39451 kka2_1:1_I221P,kka2_1:1_221,Kka2,kka2_1:1,P00552,0.394526,NO,221,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.739,-4.232,2.493,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.520039,0.00945908,0.394526 beta-lactamase_625_W288Q,beta-lactamase_625_288,TEM-1,beta-lactamase_625,P62593,0.394532,NO,288,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,,,,,,,,,,,,,BHO,,0.213352,,0.394532 kka2_1:1_C192Y,kka2_1:1_192,Kka2,kka2_1:1,P00552,0.394566,NO,192,C,Y,CY,Special,Hydrophobic,5.07,5.66,0.59,194,121,181,60,108.5,193.6,85.1,-1.067,-2.934,1.867,,0.095,.,B,0.46,-0.75,2.749,,50,HOH,-0.960333,0.520039,0.00485428,0.394566 Pab1_A185P,Pab1_185,Pab1,Pab1,P04147,0.394596,NO,185,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.702,-3.706,2.004,,,,,,,1.756,,63.26,AHH,-1.66167,0.175299,0.00144499,0.394596 beta-lactamase_2500_L218V,beta-lactamase_2500_218,TEM-1,beta-lactamase_2500,P62593,0.394611,NO,218,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.391,-3.3,1.909,,,I,b,0.55,-0.53,9.151,9.151,74.48,OHH,-1.58867,0.361275,0.00618274,0.394611 beta-lactamase_2500_T116F,beta-lactamase_2500_116,TEM-1,beta-lactamase_2500,P62593,0.394613,NO,116,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.28,-4.243,2.963,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.361275,0.00336175,0.394613 beta-lactamase_625_S201I,beta-lactamase_625_201,TEM-1,beta-lactamase_625,P62593,0.394621,NO,201,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.183,-3.765,2.582,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.213352,0.00198815,0.394621 kka2_1:1_L7F,kka2_1:1_7,Kka2,kka2_1:1,P00552,0.394627,NO,7,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.926,-3.787,1.861,,,,,,,18.934,18.934,71.59,OHB,-2.12333,0.520039,0.00269456,0.394627 beta-lactamase_2500_L197C,beta-lactamase_2500_197,TEM-1,beta-lactamase_2500,P62593,0.394651,NO,197,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.853,-4.635,3.782,,0.007,S,B,0.55,0.33,2.421,,60.14,HHP,-1.833,0.361275,0.00144602,0.394651 beta-lactamase_T179V,beta-lactamase_179,TEM-1,beta-lactamase,P62593,0.394683,NO,179,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.085,-3.247,2.162,5.07116,,E,B,0.8,-1.38,1.859,,73.08,PPH,-1.557,0.221079,0.00226045,0.394683 beta-lactamase_625_P65G,beta-lactamase_625_65,TEM-1,beta-lactamase_625,P62593,0.394707,NO,65,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.894,-3.443,2.549,,0.098,E,B,0.52,-0.62,0.3,,40.56,HOH,-1.03233,0.213352,0.00152776,0.394707 kka2_1:1_A108F,kka2_1:1_108,Kka2,kka2_1:1,P00552,0.394772,NO,108,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.061,-4.427,2.366,,0.243,.,B,0.46,-1.34,3.156,,71.59,HHO,-1.57033,0.520039,0.00751209,0.394772 kka2_1:1_Y257I,kka2_1:1_257,Kka2,kka2_1:1,P00552,0.394775,NO,257,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-1.064,-3.568,2.504,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.520039,0.0148191,0.394775 kka2_1:1_A65M,kka2_1:1_65,Kka2,kka2_1:1,P00552,0.394811,NO,65,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.744,-3.547,1.803,,0.437,H,A,0.46,-0.39,3.012,,63.64,HHB,-1.38733,0.520039,0.00709258,0.394811 kka2_1:1_G151A,kka2_1:1_151,Kka2,kka2_1:1,P00552,0.394862,NO,151,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.873,-3.018,2.145,,0.678,T,l,0.29,1.36,0.226,,49.62,HOH,-1.11433,0.520039,0.00339918,0.394862 kka2_1:2_W24I,kka2_1:2_24,Kka2,kka2_1:2,P00552,0.394869,NO,24,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-1.779,-2.156,0.377,,0.477,E,B,1.51,-0.21,2.666,,56.06,AHH,-2.24467,0.295029,0.00631564,0.394869 kka2_1:8_D216H,kka2_1:8_216,Kka2,kka2_1:8,P00552,0.395012,NO,216,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.785,-2.903,2.118,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.100394,0.00229969,0.395012 kka2_1:8_D216H,kka2_1:8_216,Kka2,kka2_1:8,P00552,0.395012,NO,216,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.785,-2.903,2.118,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.100394,0.00229969,0.395012 beta-lactamase_625_L79S,beta-lactamase_625_79,TEM-1,beta-lactamase_625,P62593,0.395128,NO,79,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.842,-3.608,2.766,,0.007,H,A,0.55,-0.16,0.935,,50.35,HHP,-1.44333,0.213352,0.000947397,0.395128 Ubiquitin_L69T,Ubiquitin_69,Uba1,Ubiquitin,P0CG48,0.395161,NO,69,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.445,-3.538,2.093,4.75624,0.051,E,B,2.89,-0.94,7.106,,34.31,BHH,-1.72933,0.205827,0.000919136,0.395161 Ubiquitin_R42S,Ubiquitin_42,Uba1,Ubiquitin,P0CG48,0.395161,NO,42,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.571,-2.692,1.121,5.07805,0.244,E,B,0.68,-0.54,1.976,,72.85,PBH,-1.38967,0.205827,0.000622265,0.395161 kka2_1:1_V153R,kka2_1:1_153,Kka2,kka2_1:1,P00552,0.395204,NO,153,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.092,-4.22,3.128,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.520039,0.00501119,0.395204 kka2_1:1_F133R,kka2_1:1_133,Kka2,kka2_1:1,P00552,0.395206,NO,133,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-0.871,-4.184,3.313,,0.178,.,B,0.58,0.43,1.999,,42.42,OHA,-0.871667,0.520039,0.00182168,0.395206 beta-lactamase_39_V42K,beta-lactamase_39_42,TEM-1,beta-lactamase_39,P62593,0.395208,NO,42,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.564,-3.817,2.253,,0.017,E,B,0.44,-0.51,1.86,,63.99,BHO,-1.042,0.0495842,0.00404515,0.395208 kka2_1:8_G205D,kka2_1:8_205,Kka2,kka2_1:8,P00552,0.395219,NO,205,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.596,-3.497,2.901,,,E,b,0.75,-1.05,,,,POH,-1.09933,0.100394,0.00221855,0.395219 kka2_1:8_G205D,kka2_1:8_205,Kka2,kka2_1:8,P00552,0.395219,NO,205,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.596,-3.497,2.901,,,E,b,0.75,-1.05,,,,POH,-1.09933,0.100394,0.00221855,0.395219 beta-lactamase_156_W227V,beta-lactamase_156_227,TEM-1,beta-lactamase_156,P62593,0.395224,NO,227,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-0.982,-3.747,2.765,,0.272,,B,0.47,-0.29,2.533,,74.48,OHH,-1.595,0.111618,0.00226019,0.395224 kka2_1:1_P167K,kka2_1:1_167,Kka2,kka2_1:1,P00552,0.395282,NO,167,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-2.403,-3.717,1.314,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.520039,0.00543203,0.395282 kka2_1:1_L170E,kka2_1:1_170,Kka2,kka2_1:1,P00552,0.395334,NO,170,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.28,-3.891,2.611,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.520039,0.00730791,0.395334 PSD95pdz3_L379W,PSD95pdz3_379,PSD95pdz3,PSD95pdz3,P31016,0.395417,NO,379,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.347,-4.779,3.432,5.37777,,,,,16.8762,,,,HHB,-1.35667,0.0758425,0.00029733,0.395417 kka2_1:4_A215P,kka2_1:4_215,Kka2,kka2_1:4,P00552,0.39547,NO,215,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.968,-3.768,2.8,,0.039,E,B,0.46,-0.59,0.754,,50.38,HHA,-1.00467,0.168804,0.00529129,0.39547 kka2_1:2_L47A,kka2_1:2_47,Kka2,kka2_1:2,P00552,0.395472,NO,47,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.265,-2.449,1.184,,0.139,E,B,0.55,-0.86,2.369,,63.26,HHH,-1.77933,0.295029,0.00509386,0.395472 beta-lactamase_2500_T178I,beta-lactamase_2500_178,TEM-1,beta-lactamase_2500,P62593,0.395484,NO,178,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-0.791,-3.56,2.769,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.361275,0.000684366,0.395484 kka2_1:4_P194N,kka2_1:4_194,Kka2,kka2_1:4,P00552,0.395484,NO,194,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.846,-3.808,2.962,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.168804,0.00314194,0.395484 kka2_1:4_W91V,kka2_1:4_91,Kka2,kka2_1:4,P00552,0.395487,NO,91,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-1.178,-3.738,2.56,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.168804,0.00358653,0.395487 beta-lactamase_2500_G52R,beta-lactamase_2500_52,TEM-1,beta-lactamase_2500,P62593,0.395548,NO,52,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.149,-3.956,2.807,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.361275,0.00340138,0.395548 beta-lactamase_625_L219G,beta-lactamase_625_219,TEM-1,beta-lactamase_625,P62593,0.395583,NO,219,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.313,-3.865,2.552,,,I,A,0.55,-0.51,5.627,,74.48,HHB,-1.21533,0.213352,0.00664345,0.395583 beta-lactamase_G242M,beta-lactamase_242,TEM-1,beta-lactamase,P62593,0.395648,NO,242,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.319,-4.824,3.505,4.68003,,E,B,0.87,-1.05,1.079,,50,BOH,-1.428,0.221079,0.00452879,0.395648 kka2_1:1_A172N,kka2_1:1_172,Kka2,kka2_1:1,P00552,0.395716,NO,172,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.757,-3.17,1.413,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.520039,0.0079265,0.395716 beta-lactamase_2500_Y262C,beta-lactamase_2500_262,TEM-1,beta-lactamase_2500,P62593,0.395729,NO,262,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.361275,0.00853516,0.395729 kka2_1:1_A166G,kka2_1:1_166,Kka2,kka2_1:1,P00552,0.395729,NO,166,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.407,-2.83,0.423,,0.534,.,B,0.46,1.03,1.147,,71.59,HHO,-2.421,0.520039,0.00799912,0.395729 beta-lactamase_625_L120Q,beta-lactamase_625_120,TEM-1,beta-lactamase_625,P62593,0.395772,NO,120,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.044,-4.124,3.08,,,H,A,0.55,-1.13,7.813,,64.69,AHO,-1.13633,0.213352,0.00143563,0.395772 kka2_1:4_R258I,kka2_1:4_258,Kka2,kka2_1:4,P00552,0.395803,NO,258,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.626,-3.905,2.279,,0.316,H,A,1.2,-0.85,2.655,,53.03,HBH,-1.25933,0.168804,0.00983174,0.395803 kka2_1:1_D118P,kka2_1:1_118,Kka2,kka2_1:1,P00552,0.395847,NO,118,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.07,-4.037,1.967,,0.61,H,A,0.75,-0.05,13.434,13.434,64.39,HAH,-1.32367,0.520039,0.0067852,0.395847 Pab1_V198P,Pab1_198,Pab1,Pab1,P04147,0.395863,NO,198,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.113,-3.697,2.584,,0.008,E,B,0.61,0.91,,,,HHH,-1.32933,0.175299,0.000268557,0.395863 kka2_1:1_L123S,kka2_1:1_123,Kka2,kka2_1:1,P00552,0.395931,NO,123,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.888,-3.661,2.773,,0.007,H,A,0.55,-0.4,1.447,,48.86,BHB,-1.301,0.520039,0.00325188,0.395931 beta-lactamase_625_N274R,beta-lactamase_625_274,TEM-1,beta-lactamase_625,P62593,0.39594,NO,274,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.213352,0.0110418,0.39594 Pab1_L142K,Pab1_142,Pab1,Pab1,P04147,0.395979,NO,142,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.039,-3.499,2.46,,0.007,H,A,0.84,-0.65,,,,HHH,-1.487,0.175299,0.000335477,0.395979 beta-lactamase_625_R242I,beta-lactamase_625_242,TEM-1,beta-lactamase_625,P62593,0.39599,NO,242,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.213352,0.00452879,0.39599 kka2_1:8_I221E,kka2_1:8_221,Kka2,kka2_1:8,P00552,0.395996,NO,221,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.739,-4.003,2.264,,,H,A,1.52,-1.15,1.599,,71.59,AHH,-1.08367,0.100394,0.00945908,0.395996 kka2_1:8_I221E,kka2_1:8_221,Kka2,kka2_1:8,P00552,0.395996,NO,221,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.739,-4.003,2.264,,,H,A,1.52,-1.15,1.599,,71.59,AHH,-1.08367,0.100394,0.00945908,0.395996 kka2_1:1_D134T,kka2_1:1_134,Kka2,kka2_1:1,P00552,0.396012,NO,134,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.969,-3.471,2.502,,0.421,B,B,0.75,0.31,2.329,,49.62,HAB,-1.057,0.520039,0.00270812,0.396012 beta-lactamase_2500_L219K,beta-lactamase_2500_219,TEM-1,beta-lactamase_2500,P62593,0.396061,NO,219,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.313,-3.875,2.562,,,I,A,0.55,-0.51,35.994,35.994,74.48,HHB,-1.21533,0.361275,0.00664345,0.396061 beta-lactamase_2500_M67F,beta-lactamase_2500_67,TEM-1,beta-lactamase_2500,P62593,0.396066,NO,67,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-2.231,-4.128,1.897,,0.006,G,P,0.55,-0.81,2.653,,65.03,HHP,-1.502,0.361275,0.00409753,0.396066 kka2_1:1_P132H,kka2_1:1_132,Kka2,kka2_1:1,P00552,0.396102,NO,132,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.775,-4.706,3.931,,0.692,.,A,0.52,0.56,0.224,,44.7,OOH,-0.825667,0.520039,0.0018489,0.396102 beta-lactamase_T158I,beta-lactamase_158,TEM-1,beta-lactamase,P62593,0.396107,NO,158,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.116,-3.731,2.615,5.32011,0.036,,B,0.98,-0.85,2.755,,69.58,HPB,-1.269,0.221079,0.00341825,0.396107 PSD95pdz3_L323Q,PSD95pdz3_323,PSD95pdz3,PSD95pdz3,P31016,0.396115,NO,323,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.347,-3.806,2.459,5.12397,,,,,13.8825,,,,OHO,-1.121,0.0758425,0.00104644,0.396115 beta-lactamase_2500_L218G,beta-lactamase_2500_218,TEM-1,beta-lactamase_2500,P62593,0.396145,NO,218,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.391,-3.644,2.253,,,I,b,0.55,-0.53,9.151,9.151,74.48,OHH,-1.58867,0.361275,0.00618274,0.396145 kka2_1:1_R122N,kka2_1:1_122,Kka2,kka2_1:1,P00552,0.396294,NO,122,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.175,-2.97,0.795,,0.487,H,A,1.2,0.26,1.356,,71.59,BBH,-1.53833,0.520039,0.00736512,0.396294 kka2_1:1_D227C,kka2_1:1_227,Kka2,kka2_1:1,P00552,0.396295,NO,227,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.758,-4.819,3.061,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.520039,0.00745029,0.396295 kka2_1:1_Q136A,kka2_1:1_136,Kka2,kka2_1:1,P00552,0.396305,NO,136,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-3.021,-3.149,0.128,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.520039,0.00624149,0.396305 beta-lactamase_156_M127P,beta-lactamase_156_127,TEM-1,beta-lactamase_156,P62593,0.396409,NO,127,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-2.251,-4.144,1.893,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.111618,0.00437927,0.396409 beta-lactamase_2500_M66Q,beta-lactamase_2500_66,TEM-1,beta-lactamase_2500,P62593,0.396469,NO,66,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.362,-3.949,2.587,,0.013,,A,0.55,-0.7,0.502,,73.08,OHH,-1.49567,0.361275,0.00412876,0.396469 kka2_1:4_A224K,kka2_1:4_224,Kka2,kka2_1:4,P00552,0.396499,NO,224,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.977,-3.586,2.609,,,H,A,0.46,-1.26,0.93,,63.64,HHP,-1.41033,0.168804,0.00352047,0.396499 kka2_1:1_A110D,kka2_1:1_110,Kka2,kka2_1:1,P00552,0.396536,NO,110,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.064,-2.796,0.732,,0.175,H,A,1.04,-1.19,11.755,,71.59,OHA,-1.91867,0.520039,0.00759851,0.396536 beta-lactamase_625_V31S,beta-lactamase_625_31,TEM-1,beta-lactamase_625,P62593,0.396607,NO,31,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.822,-3.594,1.772,,,H,A,0.44,-0.46,2.576,,73.78,BHB,-2.03767,0.213352,0.00478065,0.396607 beta-lactamase_625_L100P,beta-lactamase_625_100,TEM-1,beta-lactamase_625,P62593,0.396608,NO,100,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.218,-4.169,2.951,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.213352,0.00413885,0.396608 beta-lactamase_625_L74S,beta-lactamase_625_74,TEM-1,beta-lactamase_625,P62593,0.396671,NO,74,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.296,-3.399,2.103,,,H,A,0.55,-0.91,0.895,,50,HHO,-1.34933,0.213352,0.00493255,0.396671 kka2_1:1_D220T,kka2_1:1_220,Kka2,kka2_1:1,P00552,0.396742,NO,220,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.787,-3.448,2.661,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.520039,0.00158066,0.396742 beta-lactamase_L192N,beta-lactamase_192,TEM-1,beta-lactamase,P62593,0.396862,NO,192,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.254,-4.206,2.952,5.68899,0.095,H,A,1.3,0.35,1.756,,60.14,HHP,-1.41833,0.221079,0.00558728,0.396862 beta-lactamase_M209Q,beta-lactamase_209,TEM-1,beta-lactamase,P62593,0.396862,NO,209,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.442,-3.974,2.532,5.44502,,H,A,1.75,-0.97,1.402,,64.69,HHA,-1.52633,0.221079,0.00625021,0.396862 kka2_1:4_L170E,kka2_1:4_170,Kka2,kka2_1:4,P00552,0.396885,NO,170,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.28,-3.891,2.611,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.168804,0.00730791,0.396885 kka2_1:1_R38K,kka2_1:1_38,Kka2,kka2_1:1,P00552,0.396897,NO,38,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.207,-3.15,1.943,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.520039,0.00372499,0.396897 kka2_1:4_D220P,kka2_1:4_220,Kka2,kka2_1:4,P00552,0.396947,NO,220,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.787,-3.727,2.94,,,H,A,0.75,-1.14,1.237,,46.59,PAH,-1.152,0.168804,0.00158066,0.396947 Pab1_F170T,Pab1_170,Pab1,Pab1,P04147,0.397047,NO,170,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.269,-3.517,2.248,,0.331,E,B,0.87,-1.31,2.061,,79.72,OHH,-1.06367,0.175299,0.000540225,0.397047 beta-lactamase_625_D48R,beta-lactamase_625_48,TEM-1,beta-lactamase_625,P62593,0.397055,NO,48,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.101,-3.84,2.739,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.213352,0.0027273,0.397055 beta-lactamase_625_A34N,beta-lactamase_625_34,TEM-1,beta-lactamase_625,P62593,0.39706,NO,34,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.059,-3.965,1.906,,,H,A,0.46,-0.54,3.614,,73.78,AHA,-1.74967,0.213352,0.00407913,0.39706 kka2_1:1_D227P,kka2_1:1_227,Kka2,kka2_1:1,P00552,0.397067,NO,227,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.758,-3.728,1.97,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.520039,0.00745029,0.397067 beta-lactamase_0_G154V,beta-lactamase_0_154,TEM-1,beta-lactamase_0,P62593,0.397079,NO,154,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.823,-3.725,2.902,,0.54,T,l,0.29,-0.56,3.629,,64.69,HOA,-1.635,0.0500837,0.00180205,0.397079 kka2_1:4_L174F,kka2_1:4_174,Kka2,kka2_1:4,P00552,0.397116,NO,174,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.952,-3.775,2.823,,,H,A,0.55,-0.31,1.339,,51.89,BHB,-2.08533,0.168804,0.00438501,0.397116 kka2_1:4_R145P,kka2_1:4_145,Kka2,kka2_1:4,P00552,0.397269,NO,145,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.804,-4.038,2.234,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.168804,0.00846663,0.397269 kka2_1:1_I2C,kka2_1:1_2,Kka2,kka2_1:1,P00552,0.397294,NO,2,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.787,-4.477,2.69,,,,,,,2.329,,71.59,HHA,-1.92433,0.520039,0.00246644,0.397294 kka2_1:4_C77F,kka2_1:4_77,Kka2,kka2_1:4,P00552,0.397312,NO,77,C,F,CF,Special,Hydrophobic,5.07,3.32051,-1.74949,205,121,165,44,108.5,189.9,81.4,-1.477,-4.235,2.758,,0.229,B,b,0.46,-0.57,2.499,,63.26,OOH,-1.55667,0.168804,0.00441216,0.397312 kka2_1:4_Y257I,kka2_1:4_257,Kka2,kka2_1:4,P00552,0.397314,NO,257,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-1.064,-3.568,2.504,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.168804,0.0148191,0.397314 kka2_1:4_G189D,kka2_1:4_189,Kka2,kka2_1:4,P00552,0.397336,NO,189,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.596,-3.497,2.901,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.168804,0.00253688,0.397336 beta-lactamase_39_L205D,beta-lactamase_39_205,TEM-1,beta-lactamase_39,P62593,0.397357,NO,205,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.922,-4.118,3.196,,,H,A,0.55,-0.46,0.846,,42.31,PHH,-1.57767,0.0495842,0.00255802,0.397357 beta-lactamase_625_I280T,beta-lactamase_625_280,TEM-1,beta-lactamase_625,P62593,0.397373,NO,280,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.213352,0.0530888,0.397373 kka2_1:4_L223D,kka2_1:4_223,Kka2,kka2_1:4,P00552,0.397387,NO,223,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.861,-4.172,3.311,,,H,A,1.59,-1.24,1.268,,50,HHH,-0.854333,0.168804,0.00253574,0.397387 kka2_1:8_V97E,kka2_1:8_97,Kka2,kka2_1:8,P00552,0.397389,NO,97,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.453,-3.923,2.47,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.100394,0.00737869,0.397389 kka2_1:8_V97E,kka2_1:8_97,Kka2,kka2_1:8,P00552,0.397389,NO,97,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.453,-3.923,2.47,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.100394,0.00737869,0.397389 kka2_1:1_E235Q,kka2_1:1_235,Kka2,kka2_1:1,P00552,0.39741,NO,235,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.955,-2.458,0.503,,0.631,H,A,1.52,0.12,8.521,,65.53,OAH,-2.07267,0.520039,0.0102806,0.39741 kka2_1:8_L259W,kka2_1:8_259,Kka2,kka2_1:8,P00552,0.39745,NO,259,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.088,-5.209,4.121,,0.036,H,A,1.59,-0.15,1.83,,48.48,BHH,-1.15167,0.100394,0.0206964,0.39745 kka2_1:8_L259W,kka2_1:8_259,Kka2,kka2_1:8,P00552,0.39745,NO,259,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.088,-5.209,4.121,,0.036,H,A,1.59,-0.15,1.83,,48.48,BHH,-1.15167,0.100394,0.0206964,0.39745 kka2_1:1_K112D,kka2_1:1_112,Kka2,kka2_1:1,P00552,0.397481,NO,112,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-2.491,-3.95,1.459,,0.076,H,A,2.34,-1.37,23.433,23.433,56.06,ABH,-2.00133,0.520039,0.00645389,0.397481 Pab1_A182Y,Pab1_182,Pab1,Pab1,P04147,0.397491,NO,182,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.013,-3.98,2.967,,,H,A,0.17,0.79,,,,AHH,-1.36067,0.175299,0.000289034,0.397491 beta-lactamase_N272K,beta-lactamase_272,TEM-1,beta-lactamase,P62593,0.397504,NO,272,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-1.127,-3.27,2.143,5.37826,0.081,H,A,0.09,-0.97,1.468,,63.64,BPB,-1.56333,0.221079,0.00545371,0.397504 kka2_1:1_A9F,kka2_1:1_9,Kka2,kka2_1:1,P00552,0.397506,NO,9,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.079,-3.934,1.855,,,,,,,0.383,,71.59,BHO,-2.253,0.520039,0.00273264,0.397506 kka2_1:2_F264W,kka2_1:2_264,Kka2,kka2_1:2,P00552,0.397535,NO,264,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.02,-4.514,3.494,,0.296,.,?,0.58,0.02,2.303,,71.59,HHNA,-0.9655,0.295029,,0.397535 kka2_1:4_D62F,kka2_1:4_62,Kka2,kka2_1:4,P00552,0.397591,NO,62,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.591,-4.401,2.81,,0.262,H,A,0.29,0.08,14.756,14.756,64.39,PAA,-1.77833,0.168804,0.00744243,0.397591 kka2_1:4_F263W,kka2_1:4_263,Kka2,kka2_1:4,P00552,0.39762,NO,263,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-0.911,-4.558,3.647,,0.006,G,A,0.58,-0.12,2.284,,45.83,AHH,-0.92,0.168804,0.0172454,0.39762 beta-lactamase_39_A133I,beta-lactamase_39_133,TEM-1,beta-lactamase_39,P62593,0.397639,NO,133,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.186,-3.823,2.637,,,H,A,0.46,-0.86,0.373,,67.83,HHP,-0.988333,0.0495842,0.00468022,0.397639 kka2_1:1_E230D,kka2_1:1_230,Kka2,kka2_1:1,P00552,0.397642,NO,230,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.672,-2.56,-0.112,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.520039,0.00920051,0.397642 PSD95pdz3_G329W,PSD95pdz3_329,PSD95pdz3,PSD95pdz3,P31016,0.397654,NO,329,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.008,-4.779,3.771,4.7671,,,,,19.7075,,,,HOO,-1.16033,0.0758425,0.000974577,0.397654 kka2_1:2_Y257I,kka2_1:2_257,Kka2,kka2_1:2,P00552,0.397666,NO,257,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-1.064,-3.568,2.504,,0.022,H,A,0.21,-0.88,0.833,,52.65,HHB,-1.39333,0.295029,0.0148191,0.397666 kka2_1:1_A110N,kka2_1:1_110,Kka2,kka2_1:1,P00552,0.397759,NO,110,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.064,-3.944,1.88,,0.175,H,A,1.04,-1.19,11.755,,71.59,OHA,-1.91867,0.520039,0.00759851,0.397759 beta-lactamase_39_G234T,beta-lactamase_39_234,TEM-1,beta-lactamase_39,P62593,0.397812,NO,234,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.62,-3.646,3.026,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.0495842,0.000889577,0.397812 kka2_1:1_E17C,kka2_1:1_17,Kka2,kka2_1:1,P00552,0.397856,NO,17,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.154,-5.239,3.085,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.520039,0.00688738,0.397856 beta-lactamase_625_L191S,beta-lactamase_625_191,TEM-1,beta-lactamase_625,P62593,0.397936,NO,191,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.087,-3.562,2.475,,,H,A,0.55,0.09,1.908,,63.29,BHH,-1.445,0.213352,0.00263549,0.397936 beta-lactamase_625_L188H,beta-lactamase_625_188,TEM-1,beta-lactamase_625,P62593,0.397948,NO,188,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.166,-4.872,3.706,,,H,A,0.55,-0.3,2.982,,60.14,PHB,-1.47033,0.213352,0.00295687,0.397948 kka2_1:2_N195T,kka2_1:2_195,Kka2,kka2_1:2,P00552,0.398047,NO,195,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-0.836,-3.268,2.432,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.295029,0.00276134,0.398047 kka2_1:2_R140P,kka2_1:2_140,Kka2,kka2_1:2,P00552,0.39811,NO,140,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.351,-3.937,2.586,,0.12,H,A,1.2,0.2,0.352,,53.03,BBH,-1.885,0.295029,0.00430167,0.39811 beta-lactamase_F14N,beta-lactamase_14,TEM-1,beta-lactamase,P62593,0.398171,NO,14,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-2.736,-4.072,1.336,,,,,,,1.537,,93.01,HHH,-2.26133,0.221079,0.00277095,0.398171 kka2_1:1_M120V,kka2_1:1_120,Kka2,kka2_1:1,P00552,0.398209,NO,120,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-3.877,-2.338,-1.539,,,H,A,0.55,-0.42,2.259,,92.05,HHB,-2.16733,0.520039,0.00265808,0.398209 kka2_1:1_P132S,kka2_1:1_132,Kka2,kka2_1:1,P00552,0.398227,NO,132,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.775,-2.585,1.81,,0.692,.,A,0.52,0.56,0.224,,44.7,OOH,-0.825667,0.520039,0.0018489,0.398227 kka2_1:1_T51C,kka2_1:1_51,Kka2,kka2_1:1,P00552,0.398293,NO,51,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.199,-3.244,1.045,,0.05,E,B,0.22,-0.05,3.056,,63.64,BPA,-1.76767,0.520039,0.00628861,0.398293 kka2_1:2_W15T,kka2_1:2_15,Kka2,kka2_1:2,P00552,0.39833,NO,15,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-1.392,-3.666,2.274,,0.01,G,A,0.47,0.15,2.586,,52.27,HHH,-2.10533,0.295029,0.00585505,0.39833 kka2_1:2_M116F,kka2_1:2_116,Kka2,kka2_1:2,P00552,0.398383,NO,116,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-2.482,-3.107,0.625,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.295029,0.00745147,0.398383 kka2_1:2_N195H,kka2_1:2_195,Kka2,kka2_1:2,P00552,0.398399,NO,195,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-0.836,-4.094,3.258,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.295029,0.00276134,0.398399 beta-lactamase_625_L47G,beta-lactamase_625_47,TEM-1,beta-lactamase_625,P62593,0.398403,NO,47,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.876,-3.777,1.901,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.213352,0.00439844,0.398403 kka2_1:8_L260D,kka2_1:8_260,Kka2,kka2_1:8,P00552,0.398436,NO,260,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.741,-4.172,3.431,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.100394,0.0233782,0.398436 kka2_1:8_L260D,kka2_1:8_260,Kka2,kka2_1:8,P00552,0.398436,NO,260,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.741,-4.172,3.431,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.100394,0.0233782,0.398436 beta-lactamase_2500_K30W,beta-lactamase_2500_30,TEM-1,beta-lactamase_2500,P62593,0.398454,NO,30,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-2.307,-5.404,3.097,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.361275,0.00448593,0.398454 beta-lactamase_625_A246L,beta-lactamase_625_246,TEM-1,beta-lactamase_625,P62593,0.39858,NO,246,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.121,-1.908,-0.213,,0.01,E,B,0.46,-1.01,1.201,,73.78,HHH,-1.55633,0.213352,0.00569458,0.39858 beta-lactamase_2500_D99P,beta-lactamase_2500_99,TEM-1,beta-lactamase_2500,P62593,0.398581,NO,99,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.191,-3.8,2.609,,0.402,G,A,0.75,0.36,1.318,,64.69,PAH,-1.794,0.361275,0.00305446,0.398581 beta-lactamase_625_G249H,beta-lactamase_625_249,TEM-1,beta-lactamase_625,P62593,0.398593,NO,249,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.213352,0.00220169,0.398593 kka2_1:4_E230P,kka2_1:4_230,Kka2,kka2_1:4,P00552,0.398598,NO,230,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.672,-4.133,1.461,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.168804,0.00920051,0.398598 kka2_1:1_S114W,kka2_1:1_114,Kka2,kka2_1:1,P00552,0.398648,NO,114,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.527,-5.559,3.032,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.520039,0.00705262,0.398648 kka2_1:4_Y257V,kka2_1:4_257,Kka2,kka2_1:4,P00552,0.398719,NO,257,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-1.064,-3.391,2.327,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.168804,0.0148191,0.398719 kka2_1:1_I207F,kka2_1:1_207,Kka2,kka2_1:1,P00552,0.398756,NO,207,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.175,-3.792,2.617,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.520039,0.00611824,0.398756 kka2_1:1_E235W,kka2_1:1_235,Kka2,kka2_1:1,P00552,0.398779,NO,235,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.955,-5.585,3.63,,0.631,H,A,1.52,0.12,8.521,,65.53,OAH,-2.07267,0.520039,0.0102806,0.398779 kka2_1:1_D220R,kka2_1:1_220,Kka2,kka2_1:1,P00552,0.398809,NO,220,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.787,-4.005,3.218,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.520039,0.00158066,0.398809 beta-lactamase_625_T263R,beta-lactamase_625_263,TEM-1,beta-lactamase_625,P62593,0.398851,NO,263,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.213352,0.0110582,0.398851 kka2_1:1_P45A,kka2_1:1_45,Kka2,kka2_1:1,P00552,0.398869,NO,45,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.774,-2.227,0.453,,0.669,.,B,0.52,-0.76,4.882,,71.59,BOH,-2.152,0.520039,0.00590481,0.398869 beta-lactamase_39_A133M,beta-lactamase_39_133,TEM-1,beta-lactamase_39,P62593,0.398906,NO,133,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.186,-4.694,3.508,,,H,A,0.46,-0.86,0.373,,67.83,HHP,-0.988333,0.0495842,0.00468022,0.398906 kka2_1:2_A79F,kka2_1:2_79,Kka2,kka2_1:2,P00552,0.398922,NO,79,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.368,-4.451,2.083,,0.563,.,B,0.46,-0.43,0.475,,71.59,HHH,-1.752,0.295029,0.00664821,0.398922 kka2_1:2_A255F,kka2_1:2_255,Kka2,kka2_1:2,P00552,0.39901,NO,255,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.715,-3.34,1.625,,0.466,H,A,0.46,-0.52,5.144,,65.53,HHH,-1.71267,0.295029,0.0126809,0.39901 beta-lactamase_2500_M209A,beta-lactamase_2500_209,TEM-1,beta-lactamase_2500,P62593,0.399045,NO,209,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.442,-3.177,1.735,,,H,A,0.55,-0.97,3.229,,64.69,HHA,-1.52633,0.361275,0.00625021,0.399045 kka2_1:1_M116N,kka2_1:1_116,Kka2,kka2_1:1,P00552,0.39914,NO,116,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-2.482,-4.236,1.754,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.520039,0.00745147,0.39914 beta-lactamase_0_S122E,beta-lactamase_0_122,TEM-1,beta-lactamase_0,P62593,0.399155,NO,122,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.406,-2.103,-0.303,,0.352,H,A,0.27,-0.54,30.794,30.794,77.62,OPH,-1.39767,0.0500837,0.00497825,0.399155 beta-lactamase_625_L47R,beta-lactamase_625_47,TEM-1,beta-lactamase_625,P62593,0.399192,NO,47,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.876,-2.668,0.792,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.213352,0.00439844,0.399192 kka2_1:2_D127V,kka2_1:2_127,Kka2,kka2_1:2,P00552,0.399256,NO,127,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.364,-3.744,2.38,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.295029,0.00660501,0.399256 kka2_1:2_E96D,kka2_1:2_96,Kka2,kka2_1:2,P00552,0.399309,NO,96,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.573,-3.69,1.117,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.295029,0.00369441,0.399309 kka2_1:1_R239E,kka2_1:1_239,Kka2,kka2_1:1,P00552,0.399314,NO,239,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.949,-2.985,0.036,,0.15,H,A,1.2,-0.31,0.477,,71.59,ABH,-2.23,0.520039,0.00835326,0.399314 kka2_1:4_I115F,kka2_1:4_115,Kka2,kka2_1:4,P00552,0.399324,NO,115,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.606,-3.062,1.456,,0.105,H,A,1.52,-1.18,9.996,9.996,65.53,PHH,-2.205,0.168804,0.00836567,0.399324 kka2_1:4_F48A,kka2_1:4_48,Kka2,kka2_1:4,P00552,0.399353,NO,48,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.453,-3.34,1.887,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.168804,0.00475422,0.399353 kka2_1:1_S40W,kka2_1:1_40,Kka2,kka2_1:1,P00552,0.399374,NO,40,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.645,-5.57,2.925,,0.32,E,B,0.27,-0.9,25.997,25.997,71.59,HPH,-1.91567,0.520039,0.00693477,0.399374 kka2_1:2_A222I,kka2_1:2_222,Kka2,kka2_1:2,P00552,0.399436,NO,222,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.725,-3.589,2.864,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.295029,0.00207657,0.399436 kka2_1:8_C209Y,kka2_1:8_209,Kka2,kka2_1:8,P00552,0.399442,NO,209,C,Y,CY,Special,Hydrophobic,5.07,5.66,0.59,194,121,181,60,108.5,193.6,85.1,-0.906,-4.189,3.283,,,,a,1.5,-0.89,0.391,,19.32,AOO,-0.903,0.100394,0.00260862,0.399442 kka2_1:8_C209Y,kka2_1:8_209,Kka2,kka2_1:8,P00552,0.399442,NO,209,C,Y,CY,Special,Hydrophobic,5.07,5.66,0.59,194,121,181,60,108.5,193.6,85.1,-0.906,-4.189,3.283,,,,a,1.5,-0.89,0.391,,19.32,AOO,-0.903,0.100394,0.00260862,0.399442 kka2_1:2_D250M,kka2_1:2_250,Kka2,kka2_1:2,P00552,0.399597,NO,250,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.015,-4.907,3.892,,0.274,.,b,0.75,-0.46,3.796,,51.89,OAP,-1.83933,0.295029,0.0177103,0.399597 beta-lactamase_625_L205A,beta-lactamase_625_205,TEM-1,beta-lactamase_625,P62593,0.399623,NO,205,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.922,-3.132,2.21,,,H,A,0.55,-0.46,3.782,,42.31,PHH,-1.57767,0.213352,0.00255802,0.399623 kka2_1:1_C209A,kka2_1:1_209,Kka2,kka2_1:1,P00552,0.399638,NO,209,C,A,CA,Special,Hydrophobic,5.07,6,0.93,195,121,89,-32,108.5,88.6,-19.9,-0.906,-2.925,2.019,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.520039,0.00260862,0.399638 beta-lactamase_D212F,beta-lactamase_212,TEM-1,beta-lactamase,P62593,0.399654,NO,212,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.624,-4.334,2.71,4.9705,0.037,,b,1.3,-0.58,12.482,,74.48,HAB,-1.77667,0.221079,0.00644302,0.399654 kka2_1:1_M197T,kka2_1:1_197,Kka2,kka2_1:1,P00552,0.399739,NO,197,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.707,-2.639,0.932,,0.121,E,B,1.59,-1.19,2.097,,65.53,HHH,-1.847,0.520039,0.00921295,0.399739 kka2_1:8_A222Q,kka2_1:8_222,Kka2,kka2_1:8,P00552,0.399749,NO,222,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.725,-3.928,3.203,,,H,A,1.04,-1.21,,,,HHH,-1.10833,0.100394,0.00207657,0.399749 kka2_1:8_A222Q,kka2_1:8_222,Kka2,kka2_1:8,P00552,0.399749,NO,222,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.725,-3.928,3.203,,,H,A,1.04,-1.21,,,,HHH,-1.10833,0.100394,0.00207657,0.399749 beta-lactamase_39_C75Q,beta-lactamase_39_75,TEM-1,beta-lactamase_39,P62593,0.399752,NO,75,C,Q,CQ,Special,Polar,5.07,6.24429,1.17429,154,121,146,25,108.5,143.8,35.3,-1.245,-4.228,2.983,,,H,A,0.46,-0.87,2.369,,50,HOO,-1.24333,0.0495842,0.0034616,0.399752 kka2_1:2_D52W,kka2_1:2_52,Kka2,kka2_1:2,P00552,0.399763,NO,52,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.271,-5.394,3.123,,0.22,E,B,0.75,0.8,1.123,,71.59,PAH,-2.38367,0.295029,0.00175694,0.399763 beta-lactamase_0_T126C,beta-lactamase_0_126,TEM-1,beta-lactamase_0,P62593,0.399802,NO,126,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.122,-4.816,3.694,,0.05,H,A,0.22,-0.05,0.705,,44.41,HPH,-1.60467,0.0500837,0.00244552,0.399802 kka2_1:1_A137D,kka2_1:1_137,Kka2,kka2_1:1,P00552,0.399827,NO,137,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.156,-4.088,1.932,,0.029,H,A,0.46,0.34,1.323,,63.26,PHB,-2.559,0.520039,0.00515054,0.399827 kka2_1:8_L184E,kka2_1:8_184,Kka2,kka2_1:8,P00552,0.399854,NO,184,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.496,-3.868,2.372,,0.489,E,B,0.55,-0.06,4.495,,63.26,AHH,-1.24833,0.100394,0.00518742,0.399854 kka2_1:8_L184E,kka2_1:8_184,Kka2,kka2_1:8,P00552,0.399854,NO,184,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.496,-3.868,2.372,,0.489,E,B,0.55,-0.06,4.495,,63.26,AHH,-1.24833,0.100394,0.00518742,0.399854 beta-lactamase_156_V260N,beta-lactamase_156_260,TEM-1,beta-lactamase_156,P62593,0.399857,NO,260,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.111618,0.00471757,0.399857 kka2_1:4_K112L,kka2_1:4_112,Kka2,kka2_1:4,P00552,0.399903,NO,112,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-2.491,-2.229,-0.262,,0.076,H,A,2.34,-1.37,0.39,,56.06,ABH,-2.00133,0.168804,0.00645389,0.399903 beta-lactamase_625_I45R,beta-lactamase_625_45,TEM-1,beta-lactamase_625,P62593,0.399914,NO,45,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-2.421,-4.043,1.622,,,E,B,0.48,-0.3,3.642,,77.62,HHA,-2.30267,0.213352,0.00452842,0.399914 kka2_1:4_R202P,kka2_1:4_202,Kka2,kka2_1:4,P00552,0.399916,NO,202,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.761,-4.079,2.318,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.168804,0.00696498,0.399916 beta-lactamase_625_A40K,beta-lactamase_625_40,TEM-1,beta-lactamase_625,P62593,0.399939,NO,40,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.402,-3.658,2.256,,0.155,S,B,0.46,0.21,1.357,,73.78,OHB,-1.40267,0.213352,0.00490026,0.399939 beta-lactamase_2500_P105F,beta-lactamase_2500_105,TEM-1,beta-lactamase_2500,P62593,0.400003,NO,105,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.813,-4.48,3.667,,0.226,T,A,0.52,0.8,3.1,,63.29,POH,-1.01533,0.361275,0.0011981,0.400003 beta-lactamase_2500_G243C,beta-lactamase_2500_243,TEM-1,beta-lactamase_2500,P62593,0.400011,NO,243,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.361275,0.00464034,0.400011 kka2_1:1_Y244R,kka2_1:1_244,Kka2,kka2_1:1,P00552,0.400057,NO,244,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-0.775,-3.961,3.186,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.520039,0.00453187,0.400057 beta-lactamase_2500_R242V,beta-lactamase_2500_242,TEM-1,beta-lactamase_2500,P62593,0.400191,NO,242,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.361275,0.00452879,0.400191 beta-lactamase_625_A230W,beta-lactamase_625_230,TEM-1,beta-lactamase_625,P62593,0.400322,NO,230,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.154,-5.319,4.165,,0.01,E,B,0.46,-1.17,0.777,,50,HHA,-1.079,0.213352,0.00516841,0.400322 kka2_1:4_L193T,kka2_1:4_193,Kka2,kka2_1:4,P00552,0.400322,NO,193,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.983,-3.533,2.55,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.168804,0.00480179,0.400322 beta-lactamase_R162V,beta-lactamase_162,TEM-1,beta-lactamase,P62593,0.400352,NO,162,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.016,-3.642,2.626,5.34456,0.124,S,B,0.68,-0.37,31.656,31.656,64.69,ABH,-1.25,0.221079,0.000561334,0.400352 kka2_1:2_L107S,kka2_1:2_107,Kka2,kka2_1:2,P00552,0.400384,NO,107,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.238,-3.641,2.403,,0.197,,B,1.59,-1.1,2.68,,71.59,BHH,-2.143,0.295029,0.00561937,0.400384 beta-lactamase_2500_A246W,beta-lactamase_2500_246,TEM-1,beta-lactamase_2500,P62593,0.400443,NO,246,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.121,-5.267,3.146,,0.01,E,B,0.46,-1.01,0.753,,73.78,HHH,-1.55633,0.361275,0.00569458,0.400443 PSD95pdz3_G330R,PSD95pdz3_330,PSD95pdz3,PSD95pdz3,P31016,0.400459,NO,330,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.008,-3.615,2.607,4.68351,,,,,31.405,,,,OOA,-1.14,0.0758425,0.000962386,0.400459 hsp90_F583I,hsp90_583,hsp90,hsp90,P02829,0.400597,NO,583,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-3.22,-2.939,0,5.28185,1.112,S,l,1.1,0.87,,,,PHO,-3.003,0.368192,0.000222939,0.400597 kka2_1:2_R145M,kka2_1:2_145,Kka2,kka2_1:2,P00552,0.400618,NO,145,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.804,-4.748,2.944,,0.346,H,A,1.2,1.23,7.961,,63.64,HBP,-1.88033,0.295029,0.00846663,0.400618 beta-lactamase_39_L191P,beta-lactamase_39_191,TEM-1,beta-lactamase_39,P62593,0.400621,NO,191,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.087,-4.09,3.003,,,H,A,0.55,0.09,1.372,,63.29,BHH,-1.445,0.0495842,0.00263549,0.400621 kka2_1:1_R143G,kka2_1:1_143,Kka2,kka2_1:1,P00552,0.400659,NO,143,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.525,-3.627,1.102,,0.325,H,A,0.16,1.22,3.6,,65.53,ABH,-1.86833,0.520039,0.00662247,0.400659 kka2_1:1_E17F,kka2_1:1_17,Kka2,kka2_1:1,P00552,0.400716,NO,17,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.154,-4.494,2.34,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.520039,0.00688738,0.400716 kka2_1:4_I221C,kka2_1:4_221,Kka2,kka2_1:4,P00552,0.400865,NO,221,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.739,-4.79,3.051,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.168804,0.00945908,0.400865 kka2_1:1_S40Y,kka2_1:1_40,Kka2,kka2_1:1,P00552,0.400895,NO,40,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.645,-4.369,1.724,,0.32,E,B,0.27,-0.9,25.997,25.997,71.59,HPH,-1.91567,0.520039,0.00693477,0.400895 beta-lactamase_625_R220N,beta-lactamase_625_220,TEM-1,beta-lactamase_625,P62593,0.400927,NO,220,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-0.942,-3.516,2.574,,0.295,I,A,1.2,-0.76,5.086,,74.48,HBP,-1.33633,0.213352,0.00232421,0.400927 beta-lactamase_625_A215M,beta-lactamase_625_215,TEM-1,beta-lactamase_625,P62593,0.400945,NO,215,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.503,-4.708,3.205,,,,a,0.46,-0.93,3.583,,74.48,HHO,-1.42633,0.213352,0.00544007,0.400945 beta-lactamase_2500_R41W,beta-lactamase_2500_41,TEM-1,beta-lactamase_2500,P62593,0.400956,NO,41,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-0.942,-5.348,4.406,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.361275,0.00123327,0.400956 kka2_1:8_F256K,kka2_1:8_256,Kka2,kka2_1:8,P00552,0.400956,NO,256,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.49,-3.87,2.38,,,H,A,1.62,-0.78,1.713,,53.03,HHH,-1.423,0.100394,0.0132841,0.400956 kka2_1:8_F256K,kka2_1:8_256,Kka2,kka2_1:8,P00552,0.400956,NO,256,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.49,-3.87,2.38,,,H,A,1.62,-0.78,1.713,,53.03,HHH,-1.423,0.100394,0.0132841,0.400956 kka2_1:4_R211P,kka2_1:4_211,Kka2,kka2_1:4,P00552,0.400995,NO,211,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-0.899,-3.968,3.069,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.168804,0.00204888,0.400995 beta-lactamase_M209T,beta-lactamase_209,TEM-1,beta-lactamase,P62593,0.401083,NO,209,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.442,-3.52,2.078,5.44502,,H,A,1.75,-0.97,1.402,,64.69,HHA,-1.52633,0.221079,0.00625021,0.401083 kka2_1:1_V46E,kka2_1:1_46,Kka2,kka2_1:1,P00552,0.40112,NO,46,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-2.62,-3.655,1.035,,0.192,.,B,0.44,-1.12,20.149,20.149,92.05,OHH,-1.88633,0.520039,0.00631301,0.40112 kka2_1:2_V198M,kka2_1:2_198,Kka2,kka2_1:2,P00552,0.401178,NO,198,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.719,-3.281,1.562,,0.05,E,B,1.48,-0.95,1.074,,56.06,HHA,-1.88667,0.295029,0.00835002,0.401178 kka2_1:1_R38F,kka2_1:1_38,Kka2,kka2_1:1,P00552,0.40118,NO,38,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.207,-4.103,2.896,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.520039,0.00372499,0.40118 kka2_1:4_Y218I,kka2_1:4_218,Kka2,kka2_1:4,P00552,0.401349,NO,218,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-1.438,-3.85,2.412,,0.122,H,A,0.21,-0.69,1.022,,56.06,BHP,-1.17533,0.168804,0.0126098,0.401349 beta-lactamase_156_I280N,beta-lactamase_156_280,TEM-1,beta-lactamase_156,P62593,0.401357,NO,280,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.111618,0.0530888,0.401357 kka2_1:1_L92F,kka2_1:1_92,Kka2,kka2_1:1,P00552,0.401393,NO,92,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.893,-3.727,2.834,,0.007,E,B,0.55,-0.19,1.447,,63.26,HHH,-0.962,0.520039,0.00307177,0.401393 kka2_1:2_L103T,kka2_1:2_103,Kka2,kka2_1:2,P00552,0.40142,NO,103,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-2.362,-2.414,0.052,,0.394,T,A,0.55,-0.99,3.499,,63.64,HHP,-1.534,0.295029,0.00574792,0.40142 beta-lactamase_625_W208I,beta-lactamase_625_208,TEM-1,beta-lactamase_625,P62593,0.401423,NO,208,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-0.818,-4.01,3.192,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.213352,0.00126609,0.401423 beta-lactamase_2500_T178A,beta-lactamase_2500_178,TEM-1,beta-lactamase_2500,P62593,0.401462,NO,178,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-0.791,-2.853,2.062,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.361275,0.000684366,0.401462 kka2_1:2_R217K,kka2_1:2_217,Kka2,kka2_1:2,P00552,0.401476,NO,217,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.158,-3.143,1.985,,0.252,T,A,1.2,-0.59,0.381,,52.27,ABH,-1.127,0.295029,0.0047191,0.401476 kka2_1:1_E199Y,kka2_1:1_199,Kka2,kka2_1:1,P00552,0.401602,NO,199,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.234,-4.316,2.082,,0.508,E,B,1.04,-0.43,3.012,,65.53,HAP,-2.133,0.520039,0.00854122,0.401602 beta-lactamase_2500_G249E,beta-lactamase_2500_249,TEM-1,beta-lactamase_2500,P62593,0.401649,NO,249,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.312,,,,0.256,S,B,0.23,0.04,30.841,30.841,72.73,HOO,-1.81367,0.361275,0.00220169,0.401649 beta-lactamase_2500_L55S,beta-lactamase_2500_55,TEM-1,beta-lactamase_2500,P62593,0.40165,NO,55,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.86,-3.706,1.846,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.361275,0.00403741,0.40165 beta-lactamase_2500_T147W,beta-lactamase_2500_147,TEM-1,beta-lactamase_2500,P62593,0.401702,NO,147,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.149,-5.268,4.119,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.361275,0.00226017,0.401702 kka2_1:1_A176N,kka2_1:1_176,Kka2,kka2_1:1,P00552,0.401722,NO,176,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.621,-3.03,1.409,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.520039,0.0083587,0.401722 kka2_1:1_N195Y,kka2_1:1_195,Kka2,kka2_1:1,P00552,0.401725,NO,195,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-0.836,-4.235,3.399,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.520039,0.00276134,0.401725 beta-lactamase_625_S104M,beta-lactamase_625_104,TEM-1,beta-lactamase_625,P62593,0.401739,NO,104,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.015,-4.54,3.525,,0.04,,b,0.27,0.57,1.76,,63.29,HPO,-1.05267,0.213352,0.00218083,0.401739 kka2_1:2_P109N,kka2_1:2_109,Kka2,kka2_1:2,P00552,0.401774,NO,109,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.412,-3.924,2.512,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.295029,0.0070929,0.401774 kka2_1:4_R38D,kka2_1:4_38,Kka2,kka2_1:4,P00552,0.401834,NO,38,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.207,-3.931,2.724,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.168804,0.00372499,0.401834 beta-lactamase_2500_D155N,beta-lactamase_2500_155,TEM-1,beta-lactamase_2500,P62593,0.401904,NO,155,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.889,-2.502,1.613,,0.049,,B,0.75,-0.9,2.386,,64.69,OAB,-1.62267,0.361275,0.00135315,0.401904 kka2_1:1_E169K,kka2_1:1_169,Kka2,kka2_1:1,P00552,0.401912,NO,169,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.996,-2.672,0.676,,0.422,H,A,1.04,0.3,7.546,7.546,65.53,HAH,-1.755,0.520039,0.00730086,0.401912 kka2_1:8_D216L,kka2_1:8_216,Kka2,kka2_1:8,P00552,0.40199,NO,216,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.785,-3.835,3.05,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.100394,0.00229969,0.40199 kka2_1:8_D216L,kka2_1:8_216,Kka2,kka2_1:8,P00552,0.40199,NO,216,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.785,-3.835,3.05,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.100394,0.00229969,0.40199 kka2_1:8_I115N,kka2_1:8_115,Kka2,kka2_1:8,P00552,0.40199,NO,115,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.606,-4.227,2.621,,0.105,H,A,1.52,-1.18,4.064,,65.53,PHH,-2.205,0.100394,0.00836567,0.40199 kka2_1:8_I115N,kka2_1:8_115,Kka2,kka2_1:8,P00552,0.40199,NO,115,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.606,-4.227,2.621,,0.105,H,A,1.52,-1.18,4.064,,65.53,PHH,-2.205,0.100394,0.00836567,0.40199 kka2_1:1_F264C,kka2_1:1_264,Kka2,kka2_1:1,P00552,0.40206,NO,264,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.02,-4.944,3.924,,0.296,.,?,0.58,0.02,2.303,,71.59,HHNA,-0.9655,0.520039,,0.40206 kka2_1:1_R145T,kka2_1:1_145,Kka2,kka2_1:1,P00552,0.402122,NO,145,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.804,-3.648,1.844,,0.346,H,A,1.2,1.23,23.699,23.699,63.64,HBP,-1.88033,0.520039,0.00846663,0.402122 PSD95pdz3_L323H,PSD95pdz3_323,PSD95pdz3,PSD95pdz3,P31016,0.402147,NO,323,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.347,-4.587,3.24,5.12397,,,,,13.8825,,,,OHO,-1.121,0.0758425,0.00104644,0.402147 beta-lactamase_I140R,beta-lactamase_140,TEM-1,beta-lactamase,P62593,0.402219,NO,140,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.733,-4.193,2.46,5.29918,0.128,H,A,1,0.41,1.16,,73.08,PHO,-1.48733,0.221079,0.00597777,0.402219 kka2_1:1_E86F,kka2_1:1_86,Kka2,kka2_1:1,P00552,0.402392,NO,86,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.86,-4.247,2.387,,0.369,.,B,1.04,1.92,18.506,18.506,63.26,PAH,-1.98067,0.520039,0.00642858,0.402392 beta-lactamase_2500_D83N,beta-lactamase_2500_83,TEM-1,beta-lactamase_2500,P62593,0.40243,NO,83,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.066,-3.355,2.289,,0.354,H,A,0.75,0.22,0.239,,48.95,HAH,-1.34733,0.361275,0.00205968,0.40243 beta-lactamase_2500_G265V,beta-lactamase_2500_265,TEM-1,beta-lactamase_2500,P62593,0.402447,NO,265,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.361275,0.00811926,0.402447 beta-lactamase_G114I,beta-lactamase_114,TEM-1,beta-lactamase,P62593,0.402447,NO,114,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.094,-4.083,2.989,4.92659,0.011,,p,0.77,0.35,2.148,,41.61,AOH,-1.43733,0.221079,0.00224919,0.402447 beta-lactamase_T27Y,beta-lactamase_27,TEM-1,beta-lactamase,P62593,0.402447,NO,27,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.905,-4.144,2.239,5.39752,0.007,H,A,0.69,-0.37,0.745,,93.01,APH,-1.97933,0.221079,0.00306559,0.402447 kka2_1:2_G164N,kka2_1:2_164,Kka2,kka2_1:2,P00552,0.402467,NO,164,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.869,-2.458,1.589,,0.862,T,l,0.75,1.45,1.539,,64.39,POH,-1.828,0.295029,0.00442091,0.402467 beta-lactamase_156_T263P,beta-lactamase_156_263,TEM-1,beta-lactamase_156,P62593,0.402468,NO,263,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.111618,0.0110582,0.402468 kka2_1:8_G189F,kka2_1:8_189,Kka2,kka2_1:8,P00552,0.402478,NO,189,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.596,-4.32,3.724,,0.034,S,l,0.75,-0.99,,,,BOA,-0.739,0.100394,0.00253688,0.402478 kka2_1:8_G189F,kka2_1:8_189,Kka2,kka2_1:8,P00552,0.402478,NO,189,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.596,-4.32,3.724,,0.034,S,l,0.75,-0.99,,,,BOA,-0.739,0.100394,0.00253688,0.402478 kka2_1:8_A224R,kka2_1:8_224,Kka2,kka2_1:8,P00552,0.402498,NO,224,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.977,-3.85,2.873,,,H,A,0.46,-1.26,0.357,,63.64,HHP,-1.41033,0.100394,0.00352047,0.402498 kka2_1:8_A224R,kka2_1:8_224,Kka2,kka2_1:8,P00552,0.402498,NO,224,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.977,-3.85,2.873,,,H,A,0.46,-1.26,0.357,,63.64,HHP,-1.41033,0.100394,0.00352047,0.402498 kka2_1:8_R217G,kka2_1:8_217,Kka2,kka2_1:8,P00552,0.402498,NO,217,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.158,-3.574,2.416,,0.252,T,A,0.16,-0.59,1.151,,52.27,ABH,-1.127,0.100394,0.0047191,0.402498 kka2_1:8_R217G,kka2_1:8_217,Kka2,kka2_1:8,P00552,0.402498,NO,217,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.158,-3.574,2.416,,0.252,T,A,0.16,-0.59,1.151,,52.27,ABH,-1.127,0.100394,0.0047191,0.402498 kka2_1:2_L94Q,kka2_1:2_94,Kka2,kka2_1:2,P00552,0.402506,NO,94,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.618,-4.05,2.432,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.295029,0.00520888,0.402506 kka2_1:1_E96T,kka2_1:1_96,Kka2,kka2_1:1,P00552,0.402525,NO,96,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.573,-2.511,-0.062,,0.476,,B,1.52,-0.65,1.254,,71.59,OAH,-2.143,0.520039,0.00369441,0.402525 kka2_1:4_R147W,kka2_1:4_147,Kka2,kka2_1:4,P00552,0.40266,NO,147,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.123,-5.411,4.288,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.168804,0.00549168,0.40266 kka2_1:2_L107K,kka2_1:2_107,Kka2,kka2_1:2,P00552,0.402668,NO,107,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.238,-3.819,2.581,,0.197,,B,1.59,-1.1,2.68,,71.59,BHH,-2.143,0.295029,0.00561937,0.402668 kka2_1:4_L260I,kka2_1:4_260,Kka2,kka2_1:4,P00552,0.402673,NO,260,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.741,-2.914,2.173,,0.022,H,A,0.55,-0.52,,,,HHA,-0.845667,0.168804,0.0233782,0.402673 kka2_1:1_M197D,kka2_1:1_197,Kka2,kka2_1:1,P00552,0.402685,NO,197,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.707,-4.104,2.397,,0.121,E,B,1.59,-1.19,2.097,,65.53,HHH,-1.847,0.520039,0.00921295,0.402685 beta-lactamase_V31G,beta-lactamase_31,TEM-1,beta-lactamase,P62593,0.402769,NO,31,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.822,-3.699,1.877,5.43781,,H,A,2.78,-0.46,2.885,,73.78,BHB,-2.03767,0.221079,0.00478065,0.402769 kka2_1:1_R18W,kka2_1:1_18,Kka2,kka2_1:1,P00552,0.40279,NO,18,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.055,-5.448,3.393,,0.474,T,A,1.2,0.54,11.422,11.422,71.59,ABH,-1.821,0.520039,0.00724065,0.40279 kka2_1:2_A119G,kka2_1:2_119,Kka2,kka2_1:2,P00552,0.40288,NO,119,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.073,-2.216,1.143,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.295029,0.00441074,0.40288 beta-lactamase_156_S80P,beta-lactamase_156_80,TEM-1,beta-lactamase_156,P62593,0.40289,NO,80,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.029,-3.939,1.91,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.111618,0.00565569,0.40289 kka2_1:8_V49H,kka2_1:8_49,Kka2,kka2_1:8,P00552,0.403004,NO,49,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.614,-5.018,3.404,,,E,B,1.48,-0.77,1.31,,64.39,HHB,-1.3,0.100394,0.00615685,0.403004 kka2_1:8_V49H,kka2_1:8_49,Kka2,kka2_1:8,P00552,0.403004,NO,49,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.614,-5.018,3.404,,,E,B,1.48,-0.77,1.31,,64.39,HHB,-1.3,0.100394,0.00615685,0.403004 kka2_1:1_K50I,kka2_1:1_50,Kka2,kka2_1:1,P00552,0.403013,NO,50,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-0.833,-4.062,3.229,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.520039,0.00138626,0.403013 beta-lactamase_39_A133Y,beta-lactamase_39_133,TEM-1,beta-lactamase_39,P62593,0.403028,NO,133,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.186,-4.319,3.133,,,H,A,0.46,-0.86,0.373,,67.83,HHP,-0.988333,0.0495842,0.00468022,0.403028 kka2_1:1_L223D,kka2_1:1_223,Kka2,kka2_1:1,P00552,0.403076,NO,223,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.861,-4.172,3.311,,,H,A,0.55,-1.24,1.268,,50,HHH,-0.854333,0.520039,0.00253574,0.403076 beta-lactamase_2500_D83I,beta-lactamase_2500_83,TEM-1,beta-lactamase_2500,P62593,0.403078,NO,83,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.066,-4.081,3.015,,0.354,H,A,0.75,0.22,0.239,,48.95,HAH,-1.34733,0.361275,0.00205968,0.403078 kka2_1:1_G95Q,kka2_1:1_95,Kka2,kka2_1:1,P00552,0.403138,NO,95,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-2.403,-2.902,0.499,,0.126,E,B,0.29,-0.74,7.822,,71.59,HOA,-2.198,0.520039,0.00743616,0.403138 kka2_1:1_A71M,kka2_1:1_71,Kka2,kka2_1:1,P00552,0.403189,NO,71,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.824,-3.582,1.758,,0.553,H,A,0.46,0.08,9.788,,64.39,HHP,-1.74033,0.520039,0.00727707,0.403189 kka2_1:1_M197L,kka2_1:1_197,Kka2,kka2_1:1,P00552,0.403192,NO,197,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.707,-1.777,0.07,,0.121,E,B,1.59,-1.19,2.097,,65.53,HHH,-1.847,0.520039,0.00921295,0.403192 beta-lactamase_2500_L205W,beta-lactamase_2500_205,TEM-1,beta-lactamase_2500,P62593,0.403199,NO,205,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.922,-4.959,4.037,,,H,A,0.55,-0.46,0.831,,42.31,PHH,-1.57767,0.361275,0.00255802,0.403199 beta-lactamase_2500_A215Q,beta-lactamase_2500_215,TEM-1,beta-lactamase_2500,P62593,0.403201,NO,215,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.503,-2.998,1.495,,,,a,0.46,-0.93,3.516,,74.48,HHO,-1.42633,0.361275,0.00544007,0.403201 Ubiquitin_F4Q,Ubiquitin_4,Uba1,Ubiquitin,P0CG48,0.403226,NO,4,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.534,-4.066,2.532,4.77459,0.059,E,B,,-0.46,,,,HHH,-1.504,0.205827,0.000805043,0.403226 Ubiquitin_G10D,Ubiquitin_10,Uba1,Ubiquitin,P0CG48,0.403226,NO,10,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.396,-2.692,1.296,5.29806,0.115,S,l,,0.2,,,,POB,-1.38633,0.205827,0.000748953,0.403226 Ubiquitin_I36A,Ubiquitin_36,Uba1,Ubiquitin,P0CG48,0.403226,NO,36,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.477,-3.043,1.566,5.1035,0.203,,B,0.27,-0.22,1.552,,30.8,OHO,-1.30767,0.205827,0.000630555,0.403226 Ubiquitin_K6E,Ubiquitin_6,Uba1,Ubiquitin,P0CG48,0.403226,NO,6,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.093,-2.101,1.008,4.84211,0.35,E,B,1.82,-0.62,1.502,,71.82,HBP,-1.36133,0.205827,0.000784795,0.403226 Ubiquitin_L67K,Ubiquitin_67,Uba1,Ubiquitin,P0CG48,0.403226,NO,67,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.435,-3.616,2.181,4.92156,,E,B,1.19,-1.02,6.371,6.371,30.8,PHB,-1.628,0.205827,0.000482727,0.403226 Ubiquitin_Q41E,Ubiquitin_41,Uba1,Ubiquitin,P0CG48,0.403226,NO,41,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-1.329,-3.062,1.733,4.9201,0.017,E,B,0.12,-0.98,0.812,,30.07,PPB,-1.55067,0.205827,0.000521668,0.403226 Ubiquitin_Q49M,Ubiquitin_49,Uba1,Ubiquitin,P0CG48,0.403226,NO,49,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-1.941,-3.242,1.301,5.05026,0.403,E,B,,-0.59,,,,BPH,-1.49467,0.205827,0.000613067,0.403226 Ubiquitin_R42G,Ubiquitin_42,Uba1,Ubiquitin,P0CG48,0.403226,NO,42,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.571,-3.449,1.878,5.07805,0.244,E,B,0.68,-0.54,1.976,,72.85,PBH,-1.38967,0.205827,0.000622265,0.403226 kka2_1:8_A215D,kka2_1:8_215,Kka2,kka2_1:8,P00552,0.403265,NO,215,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.968,-3.663,2.695,,0.039,E,B,1.04,-0.59,2.77,,50.38,HHA,-1.00467,0.100394,0.00529129,0.403265 kka2_1:8_A215D,kka2_1:8_215,Kka2,kka2_1:8,P00552,0.403265,NO,215,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.968,-3.663,2.695,,0.039,E,B,1.04,-0.59,2.77,,50.38,HHA,-1.00467,0.100394,0.00529129,0.403265 kka2_1:8_A215H,kka2_1:8_215,Kka2,kka2_1:8,P00552,0.403265,NO,215,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.968,-4.735,3.767,,0.039,E,B,1.04,-0.59,2.77,,50.38,HHA,-1.00467,0.100394,0.00529129,0.403265 kka2_1:8_A215H,kka2_1:8_215,Kka2,kka2_1:8,P00552,0.403265,NO,215,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.968,-4.735,3.767,,0.039,E,B,1.04,-0.59,2.77,,50.38,HHA,-1.00467,0.100394,0.00529129,0.403265 beta-lactamase_625_A235D,beta-lactamase_625_235,TEM-1,beta-lactamase_625,P62593,0.40331,NO,235,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.266,-3.668,2.402,,0.32,E,B,0.46,-0.86,0.281,,50,OHO,-0.89,0.213352,0.00493474,0.40331 kka2_1:8_M116H,kka2_1:8_116,Kka2,kka2_1:8,P00552,0.403313,NO,116,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-2.482,-4.918,2.436,,,H,A,1.59,-0.88,4.659,,71.59,HHH,-1.63867,0.100394,0.00745147,0.403313 kka2_1:8_M116H,kka2_1:8_116,Kka2,kka2_1:8,P00552,0.403313,NO,116,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-2.482,-4.918,2.436,,,H,A,1.59,-0.88,4.659,,71.59,HHH,-1.63867,0.100394,0.00745147,0.403313 kka2_1:4_N195V,kka2_1:4_195,Kka2,kka2_1:4,P00552,0.403425,NO,195,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-0.836,-3.805,2.969,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.168804,0.00276134,0.403425 kka2_1:1_R217V,kka2_1:1_217,Kka2,kka2_1:1,P00552,0.403459,NO,217,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.158,-3.458,2.3,,0.252,T,A,1.2,-0.59,0.381,,52.27,ABH,-1.127,0.520039,0.0047191,0.403459 kka2_1:8_S32N,kka2_1:8_32,Kka2,kka2_1:8,P00552,0.40351,NO,32,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-0.804,-3.251,2.447,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.100394,0.00149998,0.40351 kka2_1:8_S32N,kka2_1:8_32,Kka2,kka2_1:8,P00552,0.40351,NO,32,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-0.804,-3.251,2.447,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.100394,0.00149998,0.40351 kka2_1:4_W69P,kka2_1:4_69,Kka2,kka2_1:4,P00552,0.403535,NO,69,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-0.859,-4.356,3.497,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.168804,0.0012874,0.403535 kka2_1:1_G30H,kka2_1:1_30,Kka2,kka2_1:1,P00552,0.403654,NO,30,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.596,-4.708,4.112,,0.54,S,g,0.29,3.76,,,,HOO,-1.51133,0.520039,0.00159208,0.403654 PSD95pdz3_G330F,PSD95pdz3_330,PSD95pdz3,PSD95pdz3,P31016,0.403724,NO,330,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.008,-3.974,2.966,4.68351,,,,,31.405,,,,OOA,-1.14,0.0758425,0.000962386,0.403724 beta-lactamase_156_E35Y,beta-lactamase_156_35,TEM-1,beta-lactamase_156,P62593,0.403753,NO,35,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-0.869,-4.211,3.342,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.111618,0.00174441,0.403753 kka2_1:4_A224S,kka2_1:4_224,Kka2,kka2_1:4,P00552,0.403764,NO,224,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.977,-3.088,2.111,,,H,A,0.46,-1.26,0.93,,63.64,HHP,-1.41033,0.168804,0.00352047,0.403764 beta-lactamase_625_M184S,beta-lactamase_625_184,TEM-1,beta-lactamase_625,P62593,0.403863,NO,184,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.593,-3.463,1.87,,,H,A,0.55,-0.87,2.765,,62.94,HHH,-1.41,0.213352,0.00356019,0.403863 kka2_1:8_F133M,kka2_1:8_133,Kka2,kka2_1:8,P00552,0.403887,NO,133,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-0.871,-4.327,3.456,,0.178,,B,1.62,0.43,1.816,,42.42,OHA,-0.871667,0.100394,0.00182168,0.403887 kka2_1:8_F133M,kka2_1:8_133,Kka2,kka2_1:8,P00552,0.403887,NO,133,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-0.871,-4.327,3.456,,0.178,,B,1.62,0.43,1.816,,42.42,OHA,-0.871667,0.100394,0.00182168,0.403887 kka2_1:4_V186G,kka2_1:4_186,Kka2,kka2_1:4,P00552,0.403947,NO,186,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.011,-3.743,2.732,,,E,B,0.44,-0.61,0.679,,45.83,HHP,-1.10967,0.168804,0.00409703,0.403947 kka2_1:8_I115E,kka2_1:8_115,Kka2,kka2_1:8,P00552,0.404013,NO,115,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.606,-3.967,2.361,,0.105,H,A,1.52,-1.18,4.064,,65.53,PHH,-2.205,0.100394,0.00836567,0.404013 kka2_1:8_I115E,kka2_1:8_115,Kka2,kka2_1:8,P00552,0.404013,NO,115,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.606,-3.967,2.361,,0.105,H,A,1.52,-1.18,4.064,,65.53,PHH,-2.205,0.100394,0.00836567,0.404013 beta-lactamase_625_G142V,beta-lactamase_625_142,TEM-1,beta-lactamase_625,P62593,0.40407,NO,142,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.707,-3.751,3.044,,0.034,,p,0.29,-0.64,1.35,,64.69,OOO,-0.834,0.213352,0.00060149,0.40407 beta-lactamase_Q204P,beta-lactamase_204,TEM-1,beta-lactamase,P62593,0.404171,NO,204,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-1.382,-3.857,2.475,5.46394,0.204,H,A,0.12,0.09,1.707,,66.08,PPH,-1.49067,0.221079,0.00364106,0.404171 kka2_1:2_A144T,kka2_1:2_144,Kka2,kka2_1:2,P00552,0.404196,NO,144,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.859,-3.269,2.41,,,H,A,0.46,0.21,6.844,,52.65,BHB,-1.72933,0.295029,0.00231095,0.404196 kka2_1:8_F203T,kka2_1:8_203,Kka2,kka2_1:8,P00552,0.404377,NO,203,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-0.911,-3.673,2.762,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.100394,0.00318738,0.404377 kka2_1:8_F203T,kka2_1:8_203,Kka2,kka2_1:8,P00552,0.404377,NO,203,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-0.911,-3.673,2.762,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.100394,0.00318738,0.404377 kka2_1:8_N195Y,kka2_1:8_195,Kka2,kka2_1:8,P00552,0.404419,NO,195,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-0.836,-4.235,3.399,,0.037,G,A,0.43,-1.36,1.108,,48.11,OPH,-1.26567,0.100394,0.00276134,0.404419 kka2_1:8_N195Y,kka2_1:8_195,Kka2,kka2_1:8,P00552,0.404419,NO,195,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-0.836,-4.235,3.399,,0.037,G,A,0.43,-1.36,1.108,,48.11,OPH,-1.26567,0.100394,0.00276134,0.404419 beta-lactamase_625_T179M,beta-lactamase_625_179,TEM-1,beta-lactamase_625,P62593,0.404472,NO,179,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.085,-4.564,3.479,,,E,B,0.22,-1.38,0.367,,73.08,PPH,-1.557,0.213352,0.00226045,0.404472 kka2_1:4_G201F,kka2_1:4_201,Kka2,kka2_1:4,P00552,0.404664,NO,201,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.56,-4.498,2.938,,0.149,T,l,0.29,-0.57,0.284,,52.65,POB,-1.92233,0.168804,0.00820117,0.404664 kka2_1:4_D261S,kka2_1:4_261,Kka2,kka2_1:4,P00552,0.404681,NO,261,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.708,-3.189,2.481,,0.146,G,A,0.75,-0.33,,,,HAA,-0.759333,0.168804,0.0224846,0.404681 kka2_1:1_A215R,kka2_1:1_215,Kka2,kka2_1:1,P00552,0.404683,NO,215,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.968,-3.821,2.853,,0.039,E,B,0.46,-0.59,0.754,,50.38,HHA,-1.00467,0.520039,0.00529129,0.404683 beta-lactamase_2500_R242L,beta-lactamase_2500_242,TEM-1,beta-lactamase_2500,P62593,0.404696,NO,242,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.361275,0.00452879,0.404696 kka2_1:4_P179S,kka2_1:4_179,Kka2,kka2_1:4,P00552,0.404738,NO,179,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.974,-2.711,1.737,,0.113,,B,0.52,0.69,10.913,10.913,56.06,HOA,-2.19867,0.168804,0.00298346,0.404738 PSD95pdz3_A375L,PSD95pdz3_375,PSD95pdz3,PSD95pdz3,P31016,0.404752,NO,375,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.307,-2.815,1.508,5.05512,,,,,13.888,,,,PHH,-1.43767,0.0758425,0.000356809,0.404752 kka2_1:1_A64D,kka2_1:1_64,Kka2,kka2_1:1,P00552,0.404893,NO,64,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.496,-3.892,2.396,,0.039,H,A,0.46,-0.57,1.175,,56.06,AHH,-1.334,0.520039,0.00705578,0.404893 kka2_1:8_G213K,kka2_1:8_213,Kka2,kka2_1:8,P00552,0.404953,NO,213,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.596,-3.71,3.114,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.100394,0.00187654,0.404953 kka2_1:8_G213K,kka2_1:8_213,Kka2,kka2_1:8,P00552,0.404953,NO,213,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.596,-3.71,3.114,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.100394,0.00187654,0.404953 kka2_1:8_G213P,kka2_1:8_213,Kka2,kka2_1:8,P00552,0.404953,NO,213,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.596,-3.908,3.312,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.100394,0.00187654,0.404953 kka2_1:8_G213P,kka2_1:8_213,Kka2,kka2_1:8,P00552,0.404953,NO,213,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.596,-3.908,3.312,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.100394,0.00187654,0.404953 beta-lactamase_625_L47H,beta-lactamase_625_47,TEM-1,beta-lactamase_625,P62593,0.404997,NO,47,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.876,-2.811,0.935,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.213352,0.00439844,0.404997 beta-lactamase_625_G142C,beta-lactamase_625_142,TEM-1,beta-lactamase_625,P62593,0.405061,NO,142,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.707,-5.05,4.343,,0.034,,p,0.29,-0.64,1.35,,64.69,OOO,-0.834,0.213352,0.00060149,0.405061 beta-lactamase_2500_L89R,beta-lactamase_2500_89,TEM-1,beta-lactamase_2500,P62593,0.40515,NO,89,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.096,-3.963,2.867,,0.168,T,A,0.55,0.63,2.066,,64.34,PHO,-1.75767,0.361275,0.00207068,0.40515 kka2_1:1_R66E,kka2_1:1_66,Kka2,kka2_1:1,P00552,0.405179,NO,66,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-0.922,-3.242,2.32,,0.103,H,A,1.2,-0.2,2.659,,46.21,HBH,-1.13567,0.520039,0.00161025,0.405179 beta-lactamase_2500_T263P,beta-lactamase_2500_263,TEM-1,beta-lactamase_2500,P62593,0.405282,NO,263,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.361275,0.0110582,0.405282 beta-lactamase_39_I258H,beta-lactamase_39_258,TEM-1,beta-lactamase_39,P62593,0.405353,NO,258,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.0495842,0.007931,0.405353 kka2_1:2_C192E,kka2_1:2_192,Kka2,kka2_1:2,P00552,0.405358,NO,192,C,E,CE,Special,negativeCharge,5.07,3.22,-1.85,170,121,147,26,108.5,138.4,29.9,-1.067,-3.955,2.888,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.295029,0.00485428,0.405358 kka2_1:1_E96K,kka2_1:1_96,Kka2,kka2_1:1,P00552,0.405362,NO,96,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.573,-3.494,0.921,,0.476,,B,1.52,-0.65,1.254,,71.59,OAH,-2.143,0.520039,0.00369441,0.405362 kka2_1:1_V36T,kka2_1:1_36,Kka2,kka2_1:1,P00552,0.405386,NO,36,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-0.898,-3.307,2.409,,0.292,E,B,0.44,0.21,0.278,,52.27,HHH,-1.484,0.520039,0.00245633,0.405386 kka2_1:1_I254D,kka2_1:1_254,Kka2,kka2_1:1,P00552,0.405439,NO,254,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.933,-4.156,2.223,,0.135,H,A,1.52,-0.6,1.859,,71.59,BHH,-1.668,0.520039,0.0132375,0.405439 kka2_1:4_D82L,kka2_1:4_82,Kka2,kka2_1:4,P00552,0.405445,NO,82,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.946,-3.65,1.704,,0.341,E,b,0.75,0.52,11.923,11.923,63.64,HAH,-1.98,0.168804,0.00637516,0.405445 kka2_1:4_D82R,kka2_1:4_82,Kka2,kka2_1:4,P00552,0.405445,NO,82,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.946,-2.957,1.011,,0.341,E,b,0.75,0.52,11.923,11.923,63.64,HAH,-1.98,0.168804,0.00637516,0.405445 beta-lactamase_2500_G281F,beta-lactamase_2500_281,TEM-1,beta-lactamase_2500,P62593,0.405576,NO,281,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.361275,0.0406482,0.405576 beta-lactamase_2500_L100K,beta-lactamase_2500_100,TEM-1,beta-lactamase_2500,P62593,0.405611,NO,100,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.218,-3.837,2.619,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.361275,0.00413885,0.405611 kka2_1:4_Y257T,kka2_1:4_257,Kka2,kka2_1:4,P00552,0.405615,NO,257,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-1.064,-3.734,2.67,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.168804,0.0148191,0.405615 beta-lactamase_39_D155R,beta-lactamase_39_155,TEM-1,beta-lactamase_39,P62593,0.405626,NO,155,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.889,-3.873,2.984,,0.049,,B,0.75,-0.9,3.208,,64.69,OAB,-1.62267,0.0495842,0.00135315,0.405626 beta-lactamase_625_S201W,beta-lactamase_625_201,TEM-1,beta-lactamase_625,P62593,0.405665,NO,201,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.183,-5.344,4.161,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.213352,0.00198815,0.405665 beta-lactamase_625_A133D,beta-lactamase_625_133,TEM-1,beta-lactamase_625,P62593,0.405716,NO,133,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.186,-3.675,2.489,,,H,A,0.46,-0.86,0.373,,67.83,HHP,-0.988333,0.213352,0.00468022,0.405716 kka2_1:1_R18N,kka2_1:1_18,Kka2,kka2_1:1,P00552,0.405754,NO,18,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.055,-3.899,1.844,,0.474,T,A,1.2,0.54,11.422,11.422,71.59,ABH,-1.821,0.520039,0.00724065,0.405754 kka2_1:1_F256V,kka2_1:1_256,Kka2,kka2_1:1,P00552,0.405855,NO,256,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.49,-3.528,2.038,,,H,A,1.62,-0.78,2.354,,53.03,HHH,-1.423,0.520039,0.0132841,0.405855 kka2_1:4_L174G,kka2_1:4_174,Kka2,kka2_1:4,P00552,0.405867,NO,174,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.952,-3.755,2.803,,,H,A,0.55,-0.31,1.339,,51.89,BHB,-2.08533,0.168804,0.00438501,0.405867 kka2_1:2_Q100G,kka2_1:2_100,Kka2,kka2_1:2,P00552,0.405965,NO,100,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.77,-3.044,0.274,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.295029,0.0066405,0.405965 beta-lactamase_625_V117H,beta-lactamase_625_117,TEM-1,beta-lactamase_625,P62593,0.405981,NO,117,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.53,-4.89,3.36,,,H,A,0.44,-0.34,1.23,,65.03,PHB,-1.741,0.213352,0.00467906,0.405981 kka2_1:2_F133I,kka2_1:2_133,Kka2,kka2_1:2,P00552,0.406005,NO,133,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-0.871,-3.407,2.536,,0.178,.,B,0.58,0.43,1.999,,42.42,OHA,-0.871667,0.295029,0.00182168,0.406005 PSD95pdz3_A347P,PSD95pdz3_347,PSD95pdz3,PSD95pdz3,P31016,0.40608,NO,347,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.307,-3.336,2.029,4.89689,,,,,15.176,,,,OHA,-1.269,0.0758425,0.00074525,0.40608 beta-lactamase_39_M209K,beta-lactamase_39_209,TEM-1,beta-lactamase_39,P62593,0.406113,NO,209,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.442,-3.673,2.231,,,H,A,0.55,-0.97,1.167,,64.69,HHA,-1.52633,0.0495842,0.00625021,0.406113 beta-lactamase_0_S256Y,beta-lactamase_0_256,TEM-1,beta-lactamase_0,P62593,0.406179,NO,256,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.0500837,0.00710634,0.406179 kka2_1:1_C31G,kka2_1:1_31,Kka2,kka2_1:1,P00552,0.406336,NO,31,C,G,CG,Special,Special,5.07,3.29388,-1.77612,159,121,75,-46,108.5,60.1,-48.4,-2.246,-3.573,1.327,,1.152,S,b,0.46,4.16,8.272,,63.26,OOP,-1.21533,0.520039,0.00681582,0.406336 kka2_1:1_K112T,kka2_1:1_112,Kka2,kka2_1:1,P00552,0.406417,NO,112,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-2.491,-2.629,0.138,,0.076,H,A,2.34,-1.37,23.433,23.433,56.06,ABH,-2.00133,0.520039,0.00645389,0.406417 gb1_A252W,gb1_252,gb1,gb1,P06654,0.406418,NO,252,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.175,-5.058,3.883,,,,,,,,,,PHA,-1.55967,0.177985,0.00125598,0.406418 gb1_V280Y,gb1_280,gb1,gb1,P06654,0.406418,NO,280,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.764,-3.882,2.118,,,,,,,0.874,,35.71,PHP,-1.63733,0.177985,0.00321577,0.406418 gb1_Y271Q,gb1_271,gb1,gb1,P06654,0.406418,NO,271,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-1.181,-3.676,2.495,,,,,,,,,,PHA,-1.92933,0.177985,0.00236544,0.406418 kka2_1:8_F263C,kka2_1:8_263,Kka2,kka2_1:8,P00552,0.406428,NO,263,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-0.911,-4.889,3.978,,0.006,G,A,1.62,-0.12,0.928,,45.83,AHH,-0.92,0.100394,0.0172454,0.406428 kka2_1:8_F263C,kka2_1:8_263,Kka2,kka2_1:8,P00552,0.406428,NO,263,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-0.911,-4.889,3.978,,0.006,G,A,1.62,-0.12,0.928,,45.83,AHH,-0.92,0.100394,0.0172454,0.406428 beta-lactamase_2500_P143I,beta-lactamase_2500_143,TEM-1,beta-lactamase_2500,P62593,0.406547,NO,143,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.967,-2.787,1.82,,0.075,H,A,0.52,-0.37,0.479,,66.78,OOB,-1.354,0.361275,0.00114551,0.406547 beta-lactamase_2500_V72W,beta-lactamase_2500_72,TEM-1,beta-lactamase_2500,P62593,0.406709,NO,72,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.658,-3.279,1.621,,,H,A,0.44,-1.03,2.079,,65.73,BHH,-1.32167,0.361275,0.00501194,0.406709 beta-lactamase_625_L219C,beta-lactamase_625_219,TEM-1,beta-lactamase_625,P62593,0.406735,NO,219,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.313,-3.103,1.79,,,I,A,0.55,-0.51,5.627,,74.48,HHB,-1.21533,0.213352,0.00664345,0.406735 beta-lactamase_625_L219E,beta-lactamase_625_219,TEM-1,beta-lactamase_625,P62593,0.406743,NO,219,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.313,-3.999,2.686,,,I,A,0.55,-0.51,5.627,,74.48,HHB,-1.21533,0.213352,0.00664345,0.406743 kka2_1:8_C77P,kka2_1:8_77,Kka2,kka2_1:8,P00552,0.406767,NO,77,C,P,CP,Special,Special,5.07,6.3,1.23,169,121,115,-6,108.5,112.7,4.2,-1.477,-4.052,2.575,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.100394,0.00441216,0.406767 kka2_1:8_C77P,kka2_1:8_77,Kka2,kka2_1:8,P00552,0.406767,NO,77,C,P,CP,Special,Special,5.07,6.3,1.23,169,121,115,-6,108.5,112.7,4.2,-1.477,-4.052,2.575,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.100394,0.00441216,0.406767 kka2_1:1_G205R,kka2_1:1_205,Kka2,kka2_1:1,P00552,0.406923,NO,205,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.596,-3.961,3.365,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.520039,0.00221855,0.406923 Pab1_I128Y,Pab1_128,Pab1,Pab1,P04147,0.406956,NO,128,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.345,-3.83,2.485,,0.008,E,B,1.68,-0.6,1.706,,78.68,PHH,-1.231,0.175299,0.00104192,0.406956 Pab1_L133Y,Pab1_133,Pab1,Pab1,P04147,0.406956,NO,133,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.039,-3.755,2.716,,0.015,,B,1.75,1.03,,,,PHB,-1.22,0.175299,0.000345939,0.406956 beta-lactamase_G236Q,beta-lactamase_236,TEM-1,beta-lactamase,P62593,0.406979,NO,236,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.784,-4.093,3.309,4.7915,0.241,,b,0.23,-0.59,1.883,,64.69,HOA,-1.36933,0.221079,0.00162372,0.406979 kka2_1:1_G181D,kka2_1:1_181,Kka2,kka2_1:1,P00552,0.407003,NO,181,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-2.698,-2.653,-0.045,,0.379,S,B,0.75,0.78,15.356,15.356,71.59,AOA,-2.21,0.520039,0.00728319,0.407003 kka2_1:4_N195Y,kka2_1:4_195,Kka2,kka2_1:4,P00552,0.407148,NO,195,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-0.836,-4.235,3.399,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.168804,0.00276134,0.407148 kka2_1:1_D261S,kka2_1:1_261,Kka2,kka2_1:1,P00552,0.407211,NO,261,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.708,-3.189,2.481,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.520039,0.0224846,0.407211 kka2_1:4_A119Y,kka2_1:4_119,Kka2,kka2_1:4,P00552,0.407248,NO,119,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.073,-4.266,3.193,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.168804,0.00441074,0.407248 beta-lactamase_2500_L47K,beta-lactamase_2500_47,TEM-1,beta-lactamase_2500,P62593,0.407287,NO,47,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.876,-3.656,1.78,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.361275,0.00439844,0.407287 kka2_1:1_L60A,kka2_1:1_60,Kka2,kka2_1:1,P00552,0.407299,NO,60,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.997,-3.185,2.188,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.520039,0.00262176,0.407299 beta-lactamase_2500_P224D,beta-lactamase_2500_224,TEM-1,beta-lactamase_2500,P62593,0.407358,NO,224,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.893,-3.513,2.62,,0.383,,B,0.52,-0.3,2.666,,74.48,HOH,-1.26433,0.361275,0.00189564,0.407358 kka2_1:8_D208V,kka2_1:8_208,Kka2,kka2_1:8,P00552,0.407529,NO,208,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.708,-3.782,3.074,,0.36,,l,0.29,-1.01,,,,HAO,-0.929667,0.100394,0.00212588,0.407529 kka2_1:8_D208V,kka2_1:8_208,Kka2,kka2_1:8,P00552,0.407529,NO,208,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.708,-3.782,3.074,,0.36,,l,0.29,-1.01,,,,HAO,-0.929667,0.100394,0.00212588,0.407529 kka2_1:1_L152N,kka2_1:1_152,Kka2,kka2_1:1,P00552,0.40754,NO,152,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.521,-4.061,2.54,,0.547,.,A,0.55,1.36,1.589,,63.64,OHH,-1.162,0.520039,0.00674868,0.40754 kka2_1:4_V153G,kka2_1:4_153,Kka2,kka2_1:4,P00552,0.407632,NO,153,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.092,-3.674,2.582,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.168804,0.00501119,0.407632 kka2_1:1_D250G,kka2_1:1_250,Kka2,kka2_1:1,P00552,0.407633,NO,250,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.015,-3.27,2.255,,0.274,.,b,0.75,-0.46,4.177,,51.89,OAP,-1.83933,0.520039,0.0177103,0.407633 kka2_1:2_G21F,kka2_1:2_21,Kka2,kka2_1:2,P00552,0.407644,NO,21,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.368,-4.373,3.005,,0.586,T,l,0.29,-0.75,2.026,,71.59,HOH,-2.10167,0.295029,0.00709648,0.407644 beta-lactamase_156_W227G,beta-lactamase_156_227,TEM-1,beta-lactamase_156,P62593,0.407706,NO,227,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-0.982,-2.451,1.469,,0.272,,B,0.47,-0.29,2.533,,74.48,OHH,-1.595,0.111618,0.00226019,0.407706 beta-lactamase_625_V214D,beta-lactamase_625_214,TEM-1,beta-lactamase_625,P62593,0.407742,NO,214,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.299,-3.873,2.574,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.213352,0.00628442,0.407742 kka2_1:1_N58T,kka2_1:1_58,Kka2,kka2_1:1,P00552,0.407783,NO,58,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-2.641,-2.933,0.292,,0.131,S,A,0.61,0.72,30.755,30.755,71.59,HPA,-1.83033,0.520039,0.00793425,0.407783 kka2_1:1_A176T,kka2_1:1_176,Kka2,kka2_1:1,P00552,0.407789,NO,176,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.621,-2.528,0.907,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.520039,0.0083587,0.407789 beta-lactamase_156_L205S,beta-lactamase_156_205,TEM-1,beta-lactamase_156,P62593,0.407855,NO,205,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.922,-3.629,2.707,,,H,A,0.55,-0.46,0.678,,42.31,PHH,-1.57767,0.111618,0.00255802,0.407855 kka2_1:2_E230L,kka2_1:2_230,Kka2,kka2_1:2,P00552,0.407889,NO,230,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.672,-3.572,0.9,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.295029,0.00920051,0.407889 kka2_1:2_W24T,kka2_1:2_24,Kka2,kka2_1:2,P00552,0.407925,NO,24,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-1.779,-3.697,1.918,,0.477,E,B,1.51,-0.21,2.666,,56.06,AHH,-2.24467,0.295029,0.00631564,0.407925 beta-lactamase_2500_V82N,beta-lactamase_2500_82,TEM-1,beta-lactamase_2500,P62593,0.408018,NO,82,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.325,-2.935,1.61,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.361275,0.00397046,0.408018 kka2_1:4_N195R,kka2_1:4_195,Kka2,kka2_1:4,P00552,0.408025,NO,195,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-0.836,-3.572,2.736,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.168804,0.00276134,0.408025 kka2_1:1_A9Q,kka2_1:1_9,Kka2,kka2_1:1,P00552,0.408063,NO,9,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.079,-3.919,1.84,,,,,,,0.383,,71.59,BHO,-2.253,0.520039,0.00273264,0.408063 PSD95pdz3_H372Y,PSD95pdz3_372,PSD95pdz3,PSD95pdz3,P31016,0.408092,NO,372,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-1.627,-2.944,1.317,5.5607,,,,,17.008,,,,PBA,-1.63033,0.0758425,0.00040301,0.408092 kka2_1:4_L70A,kka2_1:4_70,Kka2,kka2_1:4,P00552,0.408319,NO,70,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.017,-3.191,2.174,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.168804,0.00411884,0.408319 kka2_1:2_H135W,kka2_1:2_135,Kka2,kka2_1:2,P00552,0.40834,NO,135,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-1.331,-5.284,3.953,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.295029,0.00532566,0.40834 kka2_1:1_F203L,kka2_1:1_203,Kka2,kka2_1:1,P00552,0.408416,NO,203,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-0.911,-2.161,1.25,,0.26,E,B,0.58,-0.92,7.323,,63.64,BHP,-1.34167,0.520039,0.00318738,0.408416 beta-lactamase_156_V42G,beta-lactamase_156_42,TEM-1,beta-lactamase_156,P62593,0.408495,NO,42,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.564,-2.773,1.209,,0.017,E,B,0.44,-0.51,2.576,,63.99,BHO,-1.042,0.111618,0.00404515,0.408495 beta-lactamase_625_L284Y,beta-lactamase_625_284,TEM-1,beta-lactamase_625,P62593,0.408524,NO,284,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.213352,0.0686156,0.408524 kka2_1:4_D118I,kka2_1:4_118,Kka2,kka2_1:4,P00552,0.408611,NO,118,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.07,-3.314,1.244,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.168804,0.0067852,0.408611 kka2_1:1_R202I,kka2_1:1_202,Kka2,kka2_1:1,P00552,0.408663,NO,202,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.761,-3.279,1.518,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.520039,0.00696498,0.408663 kka2_1:1_A110L,kka2_1:1_110,Kka2,kka2_1:1,P00552,0.408695,NO,110,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.064,-2.329,0.265,,0.175,H,A,1.04,-1.19,11.755,,71.59,OHA,-1.91867,0.520039,0.00759851,0.408695 kka2_1:2_F203Q,kka2_1:2_203,Kka2,kka2_1:2,P00552,0.408769,NO,203,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-0.911,-4.376,3.465,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.295029,0.00318738,0.408769 kka2_1:1_M148F,kka2_1:1_148,Kka2,kka2_1:1,P00552,0.408784,NO,148,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.847,-4.011,2.164,,0.268,H,A,1.59,0.71,4.618,,64.39,BHA,-1.65467,0.520039,0.00982664,0.408784 kka2_1:8_R226D,kka2_1:8_226,Kka2,kka2_1:8,P00552,0.408892,NO,226,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.392,-3.802,2.41,,0.222,H,A,0.16,-0.71,3.818,,56.06,PBA,-1.84767,0.100394,0.0108032,0.408892 kka2_1:8_R226D,kka2_1:8_226,Kka2,kka2_1:8,P00552,0.408892,NO,226,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.392,-3.802,2.41,,0.222,H,A,0.16,-0.71,3.818,,56.06,PBA,-1.84767,0.100394,0.0108032,0.408892 kka2_1:4_D190G,kka2_1:4_190,Kka2,kka2_1:4,P00552,0.408944,NO,190,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.708,-3.161,2.453,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.168804,0.00247989,0.408944 kka2_1:1_N195L,kka2_1:1_195,Kka2,kka2_1:1,P00552,0.408949,NO,195,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-0.836,-3.655,2.819,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.520039,0.00276134,0.408949 beta-lactamase_2500_I261T,beta-lactamase_2500_261,TEM-1,beta-lactamase_2500,P62593,0.408956,NO,261,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-2.88,-1.929,-0.951,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.361275,0.0123091,0.408956 kka2_1:1_H106V,kka2_1:1_106,Kka2,kka2_1:1,P00552,0.408966,NO,106,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-3.13,-3.002,-0.128,,1.065,.,a,0.17,-0.95,2.53,,71.59,PBH,-2.10433,0.520039,0.00730778,0.408966 beta-lactamase_156_M184K,beta-lactamase_156_184,TEM-1,beta-lactamase_156,P62593,0.408974,NO,184,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.593,-3.659,2.066,,,H,A,0.55,-0.87,1.671,,62.94,HHH,-1.41,0.111618,0.00356019,0.408974 kka2_1:2_L260V,kka2_1:2_260,Kka2,kka2_1:2,P00552,0.408985,NO,260,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.741,-2.882,2.141,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.295029,0.0233782,0.408985 beta-lactamase_625_K213D,beta-lactamase_625_213,TEM-1,beta-lactamase_625,P62593,0.409085,NO,213,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.81,-3.577,1.767,,0.67,,A,2.34,0.29,3.924,,67.83,ABH,-1.57767,0.213352,0.00610411,0.409085 kka2_1:1_W24T,kka2_1:1_24,Kka2,kka2_1:1,P00552,0.40915,NO,24,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-1.779,-3.697,1.918,,0.477,E,B,0.47,-0.21,2.375,,56.06,AHH,-2.24467,0.520039,0.00631564,0.40915 kka2_1:1_E160I,kka2_1:1_160,Kka2,kka2_1:1,P00552,0.409169,NO,160,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.683,-4.13,2.447,,0.989,G,A,1.04,2.28,0.273,,71.59,AAA,-1.36133,0.520039,0.00935762,0.409169 beta-lactamase_156_V106P,beta-lactamase_156_106,TEM-1,beta-lactamase_156,P62593,0.409172,NO,106,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.218,-4.094,2.876,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.111618,0.00304168,0.409172 kka2_1:1_L184W,kka2_1:1_184,Kka2,kka2_1:1,P00552,0.409202,NO,184,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.496,-3.533,2.037,,0.489,E,B,0.55,-0.06,19.127,19.127,63.26,AHH,-1.24833,0.520039,0.00518742,0.409202 kka2_1:1_I141N,kka2_1:1_141,Kka2,kka2_1:1,P00552,0.409208,NO,141,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.495,-4.275,2.78,,0.068,H,A,0.48,-0.01,7.546,7.546,92.05,BHA,-1.689,0.520039,0.00744745,0.409208 kka2_1:1_A117T,kka2_1:1_117,Kka2,kka2_1:1,P00552,0.409264,NO,117,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.828,-3.259,2.431,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.520039,0.00282984,0.409264 beta-lactamase_625_V259S,beta-lactamase_625_259,TEM-1,beta-lactamase_625,P62593,0.4093,NO,259,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.213352,0.0070773,0.4093 beta-lactamase_A34P,beta-lactamase_34,TEM-1,beta-lactamase,P62593,0.409314,NO,34,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.059,-4.024,1.965,4.9129,,H,A,0.75,-0.54,3.614,,73.78,AHA,-1.74967,0.221079,0.00407913,0.409314 kka2_1:2_G210I,kka2_1:2_210,Kka2,kka2_1:2,P00552,0.409321,NO,210,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.095,-4.061,2.966,,0.103,T,A,0.29,-0.62,0.271,,50,OOB,-0.966667,0.295029,0.00598378,0.409321 kka2_1:4_P76Y,kka2_1:4_76,Kka2,kka2_1:4,P00552,0.409348,NO,76,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.449,-4.443,2.994,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.168804,0.00625685,0.409348 kka2_1:8_V185S,kka2_1:8_185,Kka2,kka2_1:8,P00552,0.40942,NO,185,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.045,-3.595,2.55,,0.058,E,B,1.48,-0.49,1.234,,46.97,HHH,-1.184,0.100394,0.00367031,0.40942 kka2_1:8_V185S,kka2_1:8_185,Kka2,kka2_1:8,P00552,0.40942,NO,185,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.045,-3.595,2.55,,0.058,E,B,1.48,-0.49,1.234,,46.97,HHH,-1.184,0.100394,0.00367031,0.40942 kka2_1:4_W69Q,kka2_1:4_69,Kka2,kka2_1:4,P00552,0.409505,NO,69,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-0.859,-4.151,3.292,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.168804,0.0012874,0.409505 beta-lactamase_625_A185I,beta-lactamase_625_185,TEM-1,beta-lactamase_625,P62593,0.409543,NO,185,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.406,-3.361,1.955,,,H,A,0.46,-1.02,0.365,,65.03,HHP,-1.84033,0.213352,0.00467449,0.409543 beta-lactamase_625_K53P,beta-lactamase_625_53,TEM-1,beta-lactamase_625,P62593,0.409682,NO,53,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-2.313,-3.069,0.756,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.213352,0.00383383,0.409682 kka2_1:8_R217W,kka2_1:8_217,Kka2,kka2_1:8,P00552,0.409718,NO,217,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.158,-5.446,4.288,,0.252,T,A,0.16,-0.59,1.151,,52.27,ABH,-1.127,0.100394,0.0047191,0.409718 kka2_1:8_R217W,kka2_1:8_217,Kka2,kka2_1:8,P00552,0.409718,NO,217,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.158,-5.446,4.288,,0.252,T,A,0.16,-0.59,1.151,,52.27,ABH,-1.127,0.100394,0.0047191,0.409718 kka2_1:8_V97H,kka2_1:8_97,Kka2,kka2_1:8,P00552,0.409718,NO,97,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.453,-5.043,3.59,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.100394,0.00737869,0.409718 kka2_1:8_V97H,kka2_1:8_97,Kka2,kka2_1:8,P00552,0.409718,NO,97,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.453,-5.043,3.59,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.100394,0.00737869,0.409718 kka2_1:8_D62N,kka2_1:8_62,Kka2,kka2_1:8,P00552,0.409817,NO,62,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.591,-2.947,1.356,,0.262,H,A,0.29,0.08,5.58,,64.39,PAA,-1.77833,0.100394,0.00744243,0.409817 kka2_1:8_D62N,kka2_1:8_62,Kka2,kka2_1:8,P00552,0.409817,NO,62,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.591,-2.947,1.356,,0.262,H,A,0.29,0.08,5.58,,64.39,PAA,-1.77833,0.100394,0.00744243,0.409817 kka2_1:1_F240L,kka2_1:1_240,Kka2,kka2_1:1,P00552,0.409866,NO,240,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-0.911,-2.161,1.25,,,H,A,1.62,-1.21,5.798,,50.38,BHH,-1.67267,0.520039,0.00552543,0.409866 kka2_1:1_D154T,kka2_1:1_154,Kka2,kka2_1:1,P00552,0.409943,NO,154,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.876,-3.472,2.596,,0.457,.,b,0.75,1.48,0.658,,52.65,HAP,-1.52467,0.520039,0.00292633,0.409943 beta-lactamase_625_L49E,beta-lactamase_625_49,TEM-1,beta-lactamase_625,P62593,0.409974,NO,49,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.897,-3.608,1.711,,0.131,T,A,0.55,0.04,3.112,,64.69,AHP,-1.99233,0.213352,0.00401477,0.409974 kka2_1:1_C77S,kka2_1:1_77,Kka2,kka2_1:1,P00552,0.41001,NO,77,C,S,CS,Special,Polar,5.07,5.68,0.61,112,121,105,-16,108.5,89,-19.5,-1.477,-2.746,1.269,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.520039,0.00441216,0.41001 kka2_1:4_L184H,kka2_1:4_184,Kka2,kka2_1:4,P00552,0.410019,NO,184,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.496,-4.936,3.44,,0.489,E,B,1.59,-0.06,4.495,,63.26,AHH,-1.24833,0.168804,0.00518742,0.410019 kka2_1:4_L94K,kka2_1:4_94,Kka2,kka2_1:4,P00552,0.410024,NO,94,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.618,-3.731,2.113,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.168804,0.00520888,0.410024 beta-lactamase_2500_R242Q,beta-lactamase_2500_242,TEM-1,beta-lactamase_2500,P62593,0.410053,NO,242,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.361275,0.00452879,0.410053 kka2_1:1_L39Q,kka2_1:1_39,Kka2,kka2_1:1,P00552,0.41006,NO,39,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.223,-4.313,3.09,,,E,B,0.55,-1.21,0.925,,71.59,BHP,-1.69167,0.520039,0.00493618,0.41006 kka2_1:2_D250G,kka2_1:2_250,Kka2,kka2_1:2,P00552,0.410061,NO,250,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.015,-3.27,2.255,,0.274,.,b,0.75,-0.46,3.796,,51.89,OAP,-1.83933,0.295029,0.0177103,0.410061 kka2_1:2_G95M,kka2_1:2_95,Kka2,kka2_1:2,P00552,0.410111,NO,95,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-2.403,-4.756,2.353,,0.126,E,B,0.29,-0.74,0.359,,71.59,HOA,-2.198,0.295029,0.00743616,0.410111 Pab1_G150T,Pab1_150,Pab1,Pab1,P04147,0.410138,NO,150,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.809,-3.464,2.655,,0.287,S,b,0.23,0.53,,,,HOA,-1.45233,0.175299,0.000323835,0.410138 beta-lactamase_156_D129C,beta-lactamase_156_129,TEM-1,beta-lactamase_156,P62593,0.410144,NO,129,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.816,-5.136,4.32,,,,B,0.75,-0.69,1.924,,34.97,PAP,-0.818,0.111618,0.00109178,0.410144 beta-lactamase_156_L55P,beta-lactamase_156_55,TEM-1,beta-lactamase_156,P62593,0.410223,NO,55,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.86,-4.226,2.366,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.111618,0.00403741,0.410223 kka2_1:1_C192V,kka2_1:1_192,Kka2,kka2_1:1,P00552,0.410224,NO,192,C,V,CV,Special,Hydrophobic,5.07,5.60847,0.538465,192,121,117,-4,108.5,140,31.5,-1.067,-3.41,2.343,,0.095,.,B,0.46,-0.75,2.749,,50,HOH,-0.960333,0.520039,0.00485428,0.410224 beta-lactamase_2500_G265Y,beta-lactamase_2500_265,TEM-1,beta-lactamase_2500,P62593,0.410302,NO,265,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.361275,0.00811926,0.410302 beta-lactamase_L79Y,beta-lactamase_79,TEM-1,beta-lactamase,P62593,0.410309,NO,79,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.842,-3.963,3.121,4.98681,0.007,H,A,1.07,-0.16,0.823,,50.35,HHP,-1.44333,0.221079,0.000947397,0.410309 PSD95pdz3_F325Q,PSD95pdz3_325,PSD95pdz3,PSD95pdz3,P31016,0.410317,NO,325,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.524,-4.031,2.507,5.50654,,,,,12.7236,,,,OHP,-1.314,0.0758425,0.00102273,0.410317 kka2_1:1_L170R,kka2_1:1_170,Kka2,kka2_1:1,P00552,0.410329,NO,170,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.28,-4.103,2.823,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.520039,0.00730791,0.410329 kka2_1:1_A65T,kka2_1:1_65,Kka2,kka2_1:1,P00552,0.410339,NO,65,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.744,-2.824,1.08,,0.437,H,A,0.46,-0.39,3.012,,63.64,HHB,-1.38733,0.520039,0.00709258,0.410339 beta-lactamase_2500_R242N,beta-lactamase_2500_242,TEM-1,beta-lactamase_2500,P62593,0.410347,NO,242,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.361275,0.00452879,0.410347 beta-lactamase_2500_L79I,beta-lactamase_2500_79,TEM-1,beta-lactamase_2500,P62593,0.410364,NO,79,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.842,-2.934,2.092,,0.007,H,A,0.55,-0.16,0.823,,50.35,HHP,-1.44333,0.361275,0.000947397,0.410364 beta-lactamase_39_G234E,beta-lactamase_39_234,TEM-1,beta-lactamase_39,P62593,0.410505,NO,234,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.62,-3.665,3.045,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.0495842,0.000889577,0.410505 kka2_1:1_V80G,kka2_1:1_80,Kka2,kka2_1:1,P00552,0.410515,NO,80,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.144,-3.627,2.483,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.520039,0.00488211,0.410515 kka2_1:1_S204L,kka2_1:1_204,Kka2,kka2_1:1,P00552,0.410544,NO,204,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.353,-3.418,2.065,,0.144,E,A,0.27,-1.2,3.022,,65.53,HPO,-0.953333,0.520039,0.00881794,0.410544 beta-lactamase_2500_D99C,beta-lactamase_2500_99,TEM-1,beta-lactamase_2500,P62593,0.41056,NO,99,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.191,-5.117,3.926,,0.402,G,A,0.75,0.36,1.318,,64.69,PAH,-1.794,0.361275,0.00305446,0.41056 kka2_1:1_R140V,kka2_1:1_140,Kka2,kka2_1:1,P00552,0.41056,NO,140,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.351,-3.736,2.385,,0.12,H,A,1.2,0.2,11.345,11.345,53.03,BBH,-1.885,0.520039,0.00430167,0.41056 beta-lactamase_625_A235Y,beta-lactamase_625_235,TEM-1,beta-lactamase_625,P62593,0.410617,NO,235,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.266,-4.294,3.028,,0.32,E,B,0.46,-0.86,0.281,,50,OHO,-0.89,0.213352,0.00493474,0.410617 kka2_1:2_W69D,kka2_1:2_69,Kka2,kka2_1:2,P00552,0.410648,NO,69,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-0.859,-4.17,3.311,,0.164,H,A,0.47,0.15,5.074,,38.64,PHH,-1.49967,0.295029,0.0012874,0.410648 beta-lactamase_156_S128T,beta-lactamase_156_128,TEM-1,beta-lactamase_156,P62593,0.410673,NO,128,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-0.84,-2.971,2.131,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.111618,0.00071483,0.410673 beta-lactamase_D174W,beta-lactamase_174,TEM-1,beta-lactamase,P62593,0.410824,NO,174,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.738,-5.547,4.809,5.44133,0.238,,B,1.22,-0.1,,,,PAA,-1.91233,0.221079,0.00125633,0.410824 beta-lactamase_F64Q,beta-lactamase_64,TEM-1,beta-lactamase,P62593,0.410824,NO,64,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-0.841,-4.349,3.508,5.70769,0.006,E,B,1.33,-0.95,,,,BHO,-0.892667,0.221079,0.000947691,0.410824 beta-lactamase_T131W,beta-lactamase_131,TEM-1,beta-lactamase,P62593,0.410824,NO,131,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.328,-5.315,3.987,5.0548,,H,A,0.53,-0.69,3.306,,67.48,PPH,-1.00867,0.221079,0.00345886,0.410824 beta-lactamase_2500_R242M,beta-lactamase_2500_242,TEM-1,beta-lactamase_2500,P62593,0.410856,NO,242,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.361275,0.00452879,0.410856 beta-lactamase_625_T179P,beta-lactamase_625_179,TEM-1,beta-lactamase_625,P62593,0.410861,NO,179,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.085,-3.739,2.654,,,E,B,0.22,-1.38,0.367,,73.08,PPH,-1.557,0.213352,0.00226045,0.410861 kka2_1:1_D159M,kka2_1:1_159,Kka2,kka2_1:1,P00552,0.410894,NO,159,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.82,-4.992,4.172,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.520039,0.0030485,0.410894 beta-lactamase_156_E119V,beta-lactamase_156_119,TEM-1,beta-lactamase_156,P62593,0.410933,NO,119,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.412,-3.661,2.249,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.111618,0.00386966,0.410933 beta-lactamase_2500_Y95P,beta-lactamase_2500_95,TEM-1,beta-lactamase_2500,P62593,0.410963,NO,95,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-1.715,-4.285,2.57,,0.122,,b,0.21,-0.37,2.914,,77.62,BHP,-2.16167,0.361275,0.00479449,0.410963 beta-lactamase_2500_H110I,beta-lactamase_2500_110,TEM-1,beta-lactamase_2500,P62593,0.410992,NO,110,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-1.706,-4.048,2.342,,0.341,G,a,0.17,1.08,31.31,31.31,64.69,BBH,-1.73333,0.361275,0.00441499,0.410992 kka2_1:1_A247L,kka2_1:1_247,Kka2,kka2_1:1,P00552,0.410995,NO,247,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.459,-2.722,0.263,,1.01,S,A,0.46,0.65,7.731,7.731,92.05,HHH,-2.197,0.520039,0.0102428,0.410995 kka2_1:1_E142C,kka2_1:1_142,Kka2,kka2_1:1,P00552,0.411046,NO,142,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.221,-5.114,2.893,,0.471,H,A,1.52,0.85,3.626,,65.53,HAB,-2.08033,0.520039,0.00748883,0.411046 kka2_1:1_R18E,kka2_1:1_18,Kka2,kka2_1:1,P00552,0.411075,NO,18,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.055,-2.876,0.821,,0.474,T,A,1.2,0.54,11.422,11.422,71.59,ABH,-1.821,0.520039,0.00724065,0.411075 kka2_1:1_A13F,kka2_1:1_13,Kka2,kka2_1:1,P00552,0.411085,NO,13,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.248,-4.439,2.191,,0.689,G,A,0.46,0.99,25.015,25.015,92.05,OHH,-1.646,0.520039,0.00784241,0.411085 beta-lactamase_625_V78W,beta-lactamase_625_78,TEM-1,beta-lactamase_625,P62593,0.411124,NO,78,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.459,-5.345,3.886,,,H,A,0.44,-0.47,2.045,,63.64,HHH,-1.17833,0.213352,0.00492501,0.411124 kka2_1:1_E59V,kka2_1:1_59,Kka2,kka2_1:1,P00552,0.411268,NO,59,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-0.952,-3.591,2.639,,0.187,.,L,1.04,0.62,2.648,,50.38,PAH,-1.53,0.520039,0.00280355,0.411268 Ubiquitin_D32P,Ubiquitin_32,Uba1,Ubiquitin,P0CG48,0.41129,NO,32,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.451,-3.814,2.363,4.96502,0.835,H,A,,1.4,,,,PAB,-1.47067,0.205827,0.000758819,0.41129 kka2_1:8_D220H,kka2_1:8_220,Kka2,kka2_1:8,P00552,0.411301,NO,220,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.787,-4.544,3.757,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.100394,0.00158066,0.411301 kka2_1:8_D220H,kka2_1:8_220,Kka2,kka2_1:8,P00552,0.411301,NO,220,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.787,-4.544,3.757,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.100394,0.00158066,0.411301 kka2_1:4_L19P,kka2_1:4_19,Kka2,kka2_1:4,P00552,0.411324,NO,19,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.254,-4.281,3.027,,0.08,T,A,1.59,-0.26,2.645,,65.53,BHH,-2.221,0.168804,0.00620703,0.411324 kka2_1:2_E3A,kka2_1:2_3,Kka2,kka2_1:2,P00552,0.411326,NO,3,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.199,-2.95,0.751,,,,,,,7.22,,92.05,HAP,-2.11567,0.295029,0.00267607,0.411326 beta-lactamase_2500_R273F,beta-lactamase_2500_273,TEM-1,beta-lactamase_2500,P62593,0.411365,NO,273,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.314,-4.428,2.114,,0.564,H,A,1.2,1.57,19.943,19.943,73.78,ABP,-1.841,0.361275,0.0077952,0.411365 beta-lactamase_2500_G236H,beta-lactamase_2500_236,TEM-1,beta-lactamase_2500,P62593,0.411425,NO,236,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.784,-4.704,3.92,,0.241,,b,0.29,-0.59,2.14,,64.69,HOO,-1.025,0.361275,0.00162372,0.411425 kka2_1:2_V214Y,kka2_1:2_214,Kka2,kka2_1:2,P00552,0.41144,NO,214,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.261,-4.127,2.866,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.295029,0.00692782,0.41144 beta-lactamase_2500_G114D,beta-lactamase_2500_114,TEM-1,beta-lactamase_2500,P62593,0.411444,NO,114,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.094,-3.551,2.457,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.361275,0.00224919,0.411444 kka2_1:1_D154C,kka2_1:1_154,Kka2,kka2_1:1,P00552,0.411551,NO,154,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.876,-5.188,4.312,,0.457,.,b,0.75,1.48,0.658,,52.65,HAP,-1.52467,0.520039,0.00292633,0.411551 beta-lactamase_2500_V117P,beta-lactamase_2500_117,TEM-1,beta-lactamase_2500,P62593,0.4116,NO,117,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.53,-4.14,2.61,,,H,A,0.44,-0.34,1.23,,65.03,PHB,-1.741,0.361275,0.00467906,0.4116 beta-lactamase_625_D83I,beta-lactamase_625_83,TEM-1,beta-lactamase_625,P62593,0.41166,NO,83,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.066,-4.081,3.015,,0.354,H,A,0.75,0.22,0.239,,48.95,HAH,-1.34733,0.213352,0.00205968,0.41166 kka2_1:4_E59F,kka2_1:4_59,Kka2,kka2_1:4,P00552,0.41173,NO,59,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-0.952,-4.364,3.412,,0.187,.,L,1.04,0.62,3.408,,50.38,PAH,-1.53,0.168804,0.00280355,0.41173 kka2_1:8_E262P,kka2_1:8_262,Kka2,kka2_1:8,P00552,0.4118,NO,262,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-0.829,-3.706,2.877,,0.059,G,A,1.52,-0.18,0.837,,42.42,AAH,-0.816,0.100394,0.0191586,0.4118 kka2_1:8_E262P,kka2_1:8_262,Kka2,kka2_1:8,P00552,0.4118,NO,262,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-0.829,-3.706,2.877,,0.059,G,A,1.52,-0.18,0.837,,42.42,AAH,-0.816,0.100394,0.0191586,0.4118 kka2_1:8_F264E,kka2_1:8_264,Kka2,kka2_1:8,P00552,0.411805,NO,264,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.02,-3.943,2.923,,0.296,,?,1.62,0.02,1.553,,71.59,HHO,-0.9655,0.100394,,0.411805 kka2_1:8_F264E,kka2_1:8_264,Kka2,kka2_1:8,P00552,0.411805,NO,264,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.02,-3.943,2.923,,0.296,,?,1.62,0.02,1.553,,71.59,HHO,-0.9655,0.100394,,0.411805 Pab1_G150L,Pab1_150,Pab1,Pab1,P04147,0.411821,NO,150,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.809,-3.625,2.816,,0.287,S,b,0.23,0.53,,,,HOA,-1.45233,0.175299,0.000323835,0.411821 beta-lactamase_A230F,beta-lactamase_230,TEM-1,beta-lactamase,P62593,0.411858,NO,230,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.154,-4.217,3.063,4.54336,0.01,E,B,0.75,-1.17,1.97,,50,HHA,-1.079,0.221079,0.00516841,0.411858 beta-lactamase_156_S104W,beta-lactamase_156_104,TEM-1,beta-lactamase_156,P62593,0.411875,NO,104,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.015,-5.359,4.344,,0.04,,b,0.27,0.57,4.02,,63.29,HPO,-1.05267,0.111618,0.00218083,0.411875 kka2_1:1_D127H,kka2_1:1_127,Kka2,kka2_1:1,P00552,0.411937,NO,127,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.364,-4.683,3.319,,0.573,.,B,0.75,0.45,3.414,,50.38,HAO,-1.51067,0.520039,0.00660501,0.411937 kka2_1:4_L259S,kka2_1:4_259,Kka2,kka2_1:4,P00552,0.411944,NO,259,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.088,-3.523,2.435,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.168804,0.0206964,0.411944 kka2_1:1_Q42G,kka2_1:1_42,Kka2,kka2_1:1,P00552,0.411955,NO,42,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.907,-2.492,-0.415,,1.044,T,B,0.4,-0.8,2.792,,71.59,HPO,-2.12433,0.520039,0.00679212,0.411955 beta-lactamase_2500_E272P,beta-lactamase_2500_272,TEM-1,beta-lactamase_2500,P62593,0.411993,NO,272,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.361275,0.00545371,0.411993 beta-lactamase_39_E119P,beta-lactamase_39_119,TEM-1,beta-lactamase_39,P62593,0.411998,NO,119,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.412,-3.828,2.416,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.0495842,0.00386966,0.411998 kka2_1:1_V16D,kka2_1:1_16,Kka2,kka2_1:1,P00552,0.412091,NO,16,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-3.087,-2.706,-0.381,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.520039,0.00694011,0.412091 kka2_1:1_A215C,kka2_1:1_215,Kka2,kka2_1:1,P00552,0.412098,NO,215,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.968,-4.591,3.623,,0.039,E,B,0.46,-0.59,0.754,,50.38,HHA,-1.00467,0.520039,0.00529129,0.412098 kka2_1:2_L57V,kka2_1:2_57,Kka2,kka2_1:2,P00552,0.412137,NO,57,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.898,-2.47,0.572,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.295029,0.00723769,0.412137 beta-lactamase_2500_M115T,beta-lactamase_2500_115,TEM-1,beta-lactamase_2500,P62593,0.412178,NO,115,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.389,-3.522,2.133,,0.019,E,B,0.55,0.08,3.261,,69.58,OHP,-1.25433,0.361275,0.0034337,0.412178 beta-lactamase_I140D,beta-lactamase_140,TEM-1,beta-lactamase,P62593,0.41222,NO,140,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.733,-4.079,2.346,5.29918,0.128,H,A,1,0.41,1.16,,73.08,PHO,-1.48733,0.221079,0.00597777,0.41222 kka2_1:8_L223N,kka2_1:8_223,Kka2,kka2_1:8,P00552,0.412385,NO,223,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.861,-4.196,3.335,,,H,A,1.59,-1.24,1.017,,50,HHH,-0.854333,0.100394,0.00253574,0.412385 kka2_1:8_L223N,kka2_1:8_223,Kka2,kka2_1:8,P00552,0.412385,NO,223,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.861,-4.196,3.335,,,H,A,1.59,-1.24,1.017,,50,HHH,-0.854333,0.100394,0.00253574,0.412385 beta-lactamase_625_R220I,beta-lactamase_625_220,TEM-1,beta-lactamase_625,P62593,0.412413,NO,220,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-0.942,-3.974,3.032,,0.295,I,A,1.2,-0.76,5.086,,74.48,HBP,-1.33633,0.213352,0.00232421,0.412413 kka2_1:4_C192Q,kka2_1:4_192,Kka2,kka2_1:4,P00552,0.412507,NO,192,C,Q,CQ,Special,Polar,5.07,6.24429,1.17429,154,121,146,25,108.5,143.8,35.3,-1.067,-4.263,3.196,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.168804,0.00485428,0.412507 beta-lactamase_625_P143K,beta-lactamase_625_143,TEM-1,beta-lactamase_625,P62593,0.412575,NO,143,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.967,-3.581,2.614,,0.075,H,A,0.52,-0.37,1.445,,66.78,OOB,-1.354,0.213352,0.00114551,0.412575 beta-lactamase_156_N134W,beta-lactamase_156_134,TEM-1,beta-lactamase_156,P62593,0.412578,NO,134,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-0.879,-5.545,4.666,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.111618,0.000644786,0.412578 beta-lactamase_2500_P165G,beta-lactamase_2500_165,TEM-1,beta-lactamase_2500,P62593,0.41261,NO,165,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.373,-3.429,2.056,,0.203,T,A,0.52,-0.31,0.414,,73.78,AOA,-1.359,0.361275,0.00549538,0.41261 kka2_1:1_T130P,kka2_1:1_130,Kka2,kka2_1:1,P00552,0.41266,NO,130,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.392,-4.046,1.654,,0.561,G,A,0.22,0.77,0.5,,92.05,HPO,-1.62633,0.520039,0.00804204,0.41266 kka2_1:2_P167E,kka2_1:2_167,Kka2,kka2_1:2,P00552,0.412662,NO,167,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-2.403,-3.663,1.26,,0.18,H,A,0.52,0.75,3.6,,64.39,HOH,-2.26633,0.295029,0.00543203,0.412662 beta-lactamase_2500_G52W,beta-lactamase_2500_52,TEM-1,beta-lactamase_2500,P62593,0.412722,NO,52,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.149,-5.364,4.215,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.361275,0.00340138,0.412722 kka2_1:4_K50V,kka2_1:4_50,Kka2,kka2_1:4,P00552,0.412904,NO,50,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-0.833,-3.601,2.768,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.168804,0.00138626,0.412904 kka2_1:4_V198R,kka2_1:4_198,Kka2,kka2_1:4,P00552,0.413028,NO,198,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.719,-3.986,2.267,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.168804,0.00835002,0.413028 beta-lactamase_0_L120N,beta-lactamase_0_120,TEM-1,beta-lactamase_0,P62593,0.413094,NO,120,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.044,-4.027,2.983,,,H,A,0.55,-1.13,1.2,,64.69,AHO,-1.13633,0.0500837,0.00143563,0.413094 beta-lactamase_625_P65K,beta-lactamase_625_65,TEM-1,beta-lactamase_625,P62593,0.413117,NO,65,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.894,-3.511,2.617,,0.098,E,B,0.52,-0.62,0.3,,40.56,HOH,-1.03233,0.213352,0.00152776,0.413117 kka2_1:2_V186M,kka2_1:2_186,Kka2,kka2_1:2,P00552,0.413117,NO,186,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.011,-4.138,3.127,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.295029,0.00409703,0.413117 kka2_1:4_R211H,kka2_1:4_211,Kka2,kka2_1:4,P00552,0.413149,NO,211,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-0.899,-4.319,3.42,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.168804,0.00204888,0.413149 beta-lactamase_156_E119I,beta-lactamase_156_119,TEM-1,beta-lactamase_156,P62593,0.413187,NO,119,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.412,-4.096,2.684,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.111618,0.00386966,0.413187 kka2_1:2_G55K,kka2_1:2_55,Kka2,kka2_1:2,P00552,0.413228,NO,55,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.625,-3.726,2.101,,0.517,S,b,0.75,1.19,15.753,15.753,63.64,POH,-2.05967,0.295029,0.00667877,0.413228 beta-lactamase_625_V117E,beta-lactamase_625_117,TEM-1,beta-lactamase_625,P62593,0.413241,NO,117,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.53,-3.909,2.379,,,H,A,0.44,-0.34,1.23,,65.03,PHB,-1.741,0.213352,0.00467906,0.413241 beta-lactamase_2500_T198W,beta-lactamase_2500_198,TEM-1,beta-lactamase_2500,P62593,0.413384,NO,198,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.168,-5.419,3.251,,0.489,,B,0.22,-0.13,0.37,,73.78,HPH,-1.98767,0.361275,0.004311,0.413384 beta-lactamase_625_M209A,beta-lactamase_625_209,TEM-1,beta-lactamase_625,P62593,0.413421,NO,209,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.442,-3.177,1.735,,,H,A,0.55,-0.97,1.167,,64.69,HHA,-1.52633,0.213352,0.00625021,0.413421 kka2_1:1_Q136I,kka2_1:1_136,Kka2,kka2_1:1,P00552,0.413422,NO,136,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-3.021,-4.106,1.085,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.520039,0.00624149,0.413422 kka2_1:1_S32T,kka2_1:1_32,Kka2,kka2_1:1,P00552,0.413551,NO,32,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-0.804,-3,2.196,,0.768,S,b,0.27,3.75,,,,OPA,-1.74533,0.520039,0.00149998,0.413551 kka2_1:1_D127R,kka2_1:1_127,Kka2,kka2_1:1,P00552,0.41373,NO,127,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.364,-3.039,1.675,,0.573,.,B,0.75,0.45,3.414,,50.38,HAO,-1.51067,0.520039,0.00660501,0.41373 kka2_1:8_I196D,kka2_1:8_196,Kka2,kka2_1:8,P00552,0.413759,NO,196,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-2.115,-4.156,2.041,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.100394,0.0107273,0.413759 kka2_1:8_I196D,kka2_1:8_196,Kka2,kka2_1:8,P00552,0.413759,NO,196,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-2.115,-4.156,2.041,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.100394,0.0107273,0.413759 kka2_1:1_A87H,kka2_1:1_87,Kka2,kka2_1:1,P00552,0.413918,NO,87,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.917,-3.188,1.271,,1.039,S,L,0.46,1.57,20.738,20.738,65.53,AHO,-1.822,0.520039,0.00791281,0.413918 kka2_1:1_A35P,kka2_1:1_35,Kka2,kka2_1:1,P00552,0.413925,NO,35,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.127,-4.029,1.902,,0.107,E,B,0.46,1.05,8.405,8.405,71.59,HHH,-1.31767,0.520039,0.00630016,0.413925 beta-lactamase_156_I229G,beta-lactamase_156_229,TEM-1,beta-lactamase_156,P62593,0.413936,NO,229,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.267,-3.782,2.515,,0.083,E,B,0.48,-0.76,1.114,,50,HHH,-1.58767,0.111618,0.00477249,0.413936 beta-lactamase_2500_L160P,beta-lactamase_2500_160,TEM-1,beta-lactamase_2500,P62593,0.413936,NO,160,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.977,-4.121,3.144,,0.022,,B,0.55,-0.6,0.895,,44.41,BHA,-0.936,0.361275,0.00193775,0.413936 kka2_1:8_F263T,kka2_1:8_263,Kka2,kka2_1:8,P00552,0.413955,NO,263,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-0.911,-3.673,2.762,,0.006,G,A,1.62,-0.12,0.928,,45.83,AHH,-0.92,0.100394,0.0172454,0.413955 kka2_1:8_F263T,kka2_1:8_263,Kka2,kka2_1:8,P00552,0.413955,NO,263,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-0.911,-3.673,2.762,,0.006,G,A,1.62,-0.12,0.928,,45.83,AHH,-0.92,0.100394,0.0172454,0.413955 kka2_1:1_D154E,kka2_1:1_154,Kka2,kka2_1:1,P00552,0.413987,NO,154,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.876,-2.369,1.493,,0.457,.,b,0.75,1.48,0.658,,52.65,HAP,-1.52467,0.520039,0.00292633,0.413987 beta-lactamase_2500_L100S,beta-lactamase_2500_100,TEM-1,beta-lactamase_2500,P62593,0.41401,NO,100,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.218,-3.715,2.497,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.361275,0.00413885,0.41401 hsp90_N588P,hsp90_588,hsp90,hsp90,P02829,0.414053,NO,588,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-3.051,-3.033,0,4.61142,0.019,H,A,0.14,0.39,,,,HPH,-3.12167,0.368192,0.000222939,0.414053 kka2_1:4_F264C,kka2_1:4_264,Kka2,kka2_1:4,P00552,0.414074,NO,264,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.02,-4.944,3.924,,0.296,,?,1.62,0.02,1.93,,71.59,HHO,-0.9655,0.168804,,0.414074 kka2_1:1_L103F,kka2_1:1_103,Kka2,kka2_1:1,P00552,0.414116,NO,103,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-2.362,-4.185,1.823,,0.394,T,A,0.55,-0.99,4.121,,63.64,HHP,-1.534,0.520039,0.00574792,0.414116 beta-lactamase_2500_G240A,beta-lactamase_2500_240,TEM-1,beta-lactamase_2500,P62593,0.41413,NO,240,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.361275,0.00591201,0.41413 kka2_1:8_N195V,kka2_1:8_195,Kka2,kka2_1:8,P00552,0.414151,NO,195,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-0.836,-3.805,2.969,,0.037,G,A,0.43,-1.36,1.108,,48.11,OPH,-1.26567,0.100394,0.00276134,0.414151 kka2_1:8_N195V,kka2_1:8_195,Kka2,kka2_1:8,P00552,0.414151,NO,195,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-0.836,-3.805,2.969,,0.037,G,A,0.43,-1.36,1.108,,48.11,OPH,-1.26567,0.100394,0.00276134,0.414151 kka2_1:2_V36E,kka2_1:2_36,Kka2,kka2_1:2,P00552,0.414157,NO,36,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-0.898,-3.776,2.878,,0.292,E,B,1.48,0.21,1.064,,52.27,HHH,-1.484,0.295029,0.00245633,0.414157 kka2_1:2_P132I,kka2_1:2_132,Kka2,kka2_1:2,P00552,0.414193,NO,132,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.775,-4.037,3.262,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.295029,0.0018489,0.414193 kka2_1:4_G189Y,kka2_1:4_189,Kka2,kka2_1:4,P00552,0.414273,NO,189,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.596,-4.416,3.82,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.168804,0.00253688,0.414273 beta-lactamase_2500_G114N,beta-lactamase_2500_114,TEM-1,beta-lactamase_2500,P62593,0.414275,NO,114,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.094,-2.731,1.637,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.361275,0.00224919,0.414275 beta-lactamase_2500_G114W,beta-lactamase_2500_114,TEM-1,beta-lactamase_2500,P62593,0.414275,NO,114,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.094,-5.288,4.194,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.361275,0.00224919,0.414275 Pab1_F149T,Pab1_149,Pab1,Pab1,P04147,0.414292,NO,149,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.149,-3.464,2.315,,0.183,T,A,1.33,1.09,,,,HHO,-1.27767,0.175299,0.000325688,0.414292 beta-lactamase_A215W,beta-lactamase_215,TEM-1,beta-lactamase,P62593,0.414314,NO,215,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.503,-5.336,3.833,4.82164,,,a,0.75,-0.93,3.583,,74.48,HHO,-1.42633,0.221079,0.00544007,0.414314 kka2_1:4_R173P,kka2_1:4_173,Kka2,kka2_1:4,P00552,0.414336,NO,173,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.407,-4.037,1.63,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.168804,0.00784999,0.414336 kka2_1:1_K138G,kka2_1:1_138,Kka2,kka2_1:1,P00552,0.414368,NO,138,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-2.5,-2.938,0.438,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.520039,0.00628542,0.414368 kka2_1:1_D118I,kka2_1:1_118,Kka2,kka2_1:1,P00552,0.414385,NO,118,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.07,-3.314,1.244,,0.61,H,A,0.75,-0.05,13.434,13.434,64.39,HAH,-1.32367,0.520039,0.0067852,0.414385 kka2_1:1_L184Y,kka2_1:1_184,Kka2,kka2_1:1,P00552,0.414405,NO,184,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.496,-4.144,2.648,,0.489,E,B,0.55,-0.06,19.127,19.127,63.26,AHH,-1.24833,0.520039,0.00518742,0.414405 beta-lactamase_S104K,beta-lactamase_104,TEM-1,beta-lactamase,P62593,0.414427,NO,104,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.015,-3.372,2.357,4.92365,0.04,,b,0.82,0.57,4.02,,63.29,HPO,-1.05267,0.221079,0.00218083,0.414427 kka2_1:8_V97D,kka2_1:8_97,Kka2,kka2_1:8,P00552,0.414445,NO,97,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.453,-4.157,2.704,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.100394,0.00737869,0.414445 kka2_1:8_V97D,kka2_1:8_97,Kka2,kka2_1:8,P00552,0.414445,NO,97,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.453,-4.157,2.704,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.100394,0.00737869,0.414445 kka2_1:4_Q163P,kka2_1:4_163,Kka2,kka2_1:4,P00552,0.414479,NO,163,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.162,-4.062,1.9,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.168804,0.00719507,0.414479 beta-lactamase_Y44A,beta-lactamase_44,TEM-1,beta-lactamase,P62593,0.414485,NO,44,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-2.547,-2.301,-0.246,5.6273,,E,B,2.55,-0.45,2.683,,73.78,OHH,-1.86267,0.221079,0.00426364,0.414485 kka2_1:1_G189R,kka2_1:1_189,Kka2,kka2_1:1,P00552,0.414491,NO,189,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.596,-3.961,3.365,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.520039,0.00253688,0.414491 beta-lactamase_2500_D212Y,beta-lactamase_2500_212,TEM-1,beta-lactamase_2500,P62593,0.414574,NO,212,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.624,-4.398,2.774,,0.037,,b,0.75,-0.58,12.482,,74.48,HAB,-1.77667,0.361275,0.00644302,0.414574 kka2_1:2_D90E,kka2_1:2_90,Kka2,kka2_1:2,P00552,0.414622,NO,90,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.459,-2.578,0.119,,0.104,E,B,0.75,0.73,6.085,,64.39,BAH,-1.72833,0.295029,0.00583842,0.414622 PSD95pdz3_I341H,PSD95pdz3_341,PSD95pdz3,PSD95pdz3,P31016,0.414629,NO,341,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.63,-4.587,2.957,5.73946,,,,,10.3187,,,,HHH,-1.50033,0.0758425,0.000824087,0.414629 kka2_1:8_F133R,kka2_1:8_133,Kka2,kka2_1:8,P00552,0.414669,NO,133,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-0.871,-4.184,3.313,,0.178,,B,1.62,0.43,1.816,,42.42,OHA,-0.871667,0.100394,0.00182168,0.414669 kka2_1:8_F133R,kka2_1:8_133,Kka2,kka2_1:8,P00552,0.414669,NO,133,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-0.871,-4.184,3.313,,0.178,,B,1.62,0.43,1.816,,42.42,OHA,-0.871667,0.100394,0.00182168,0.414669 beta-lactamase_2500_A40L,beta-lactamase_2500_40,TEM-1,beta-lactamase_2500,P62593,0.414697,NO,40,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.402,-3.399,1.997,,0.155,S,B,0.46,0.21,0.953,,73.78,OHB,-1.40267,0.361275,0.00490026,0.414697 beta-lactamase_156_D155A,beta-lactamase_156_155,TEM-1,beta-lactamase_156,P62593,0.414706,NO,155,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.889,-3.327,2.438,,0.049,,B,0.75,-0.9,0.315,,64.69,OAB,-1.62267,0.111618,0.00135315,0.414706 kka2_1:1_D118H,kka2_1:1_118,Kka2,kka2_1:1,P00552,0.414775,NO,118,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.07,-3.064,0.994,,0.61,H,A,0.75,-0.05,13.434,13.434,64.39,HAH,-1.32367,0.520039,0.0067852,0.414775 kka2_1:1_L165K,kka2_1:1_165,Kka2,kka2_1:1,P00552,0.414795,NO,165,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-2.453,-2.336,-0.117,,0.299,,B,1.59,1.12,2.47,,64.39,OHH,-1.90967,0.520039,0.00801161,0.414795 beta-lactamase_156_L47D,beta-lactamase_156_47,TEM-1,beta-lactamase_156,P62593,0.414811,NO,47,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.876,-3.931,2.055,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.111618,0.00439844,0.414811 kka2_1:1_L107Q,kka2_1:1_107,Kka2,kka2_1:1,P00552,0.41487,NO,107,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.238,-4.215,2.977,,0.197,.,B,0.55,-1.1,3.542,,71.59,BHH,-2.143,0.520039,0.00561937,0.41487 kka2_1:2_V49R,kka2_1:2_49,Kka2,kka2_1:2,P00552,0.414874,NO,49,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.614,-4.154,2.54,,,E,B,0.44,-0.77,1.233,,64.39,HHB,-1.3,0.295029,0.00615685,0.414874 beta-lactamase_L188N,beta-lactamase_188,TEM-1,beta-lactamase,P62593,0.414885,NO,188,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.166,-4.122,2.956,5.55434,,H,A,1.07,-0.3,1.574,,60.14,PHB,-1.47033,0.221079,0.00295687,0.414885 beta-lactamase_39_T187P,beta-lactamase_39_187,TEM-1,beta-lactamase_39,P62593,0.414966,NO,187,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.401,-3.906,2.505,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.0495842,0.00491782,0.414966 beta-lactamase_39_L74H,beta-lactamase_39_74,TEM-1,beta-lactamase_39,P62593,0.414973,NO,74,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.296,-4.896,3.6,,,H,A,0.55,-0.91,1.581,,50,HHO,-1.34933,0.0495842,0.00493255,0.414973 beta-lactamase_625_M209F,beta-lactamase_625_209,TEM-1,beta-lactamase_625,P62593,0.414974,NO,209,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.442,-2.51,1.068,,,H,A,0.55,-0.97,1.167,,64.69,HHA,-1.52633,0.213352,0.00625021,0.414974 kka2_1:2_L259T,kka2_1:2_259,Kka2,kka2_1:2,P00552,0.415097,NO,259,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.088,-2.444,1.356,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.295029,0.0206964,0.415097 kka2_1:1_D180S,kka2_1:1_180,Kka2,kka2_1:1,P00552,0.415143,NO,180,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.416,-2.79,0.374,,1.03,S,a,0.75,1.5,1.534,,71.59,OAO,-2.02933,0.520039,0.00756412,0.415143 kka2_1:4_C209P,kka2_1:4_209,Kka2,kka2_1:4,P00552,0.415187,NO,209,C,P,CP,Special,Special,5.07,6.3,1.23,169,121,115,-6,108.5,112.7,4.2,-0.906,-4.156,3.25,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.168804,0.00260862,0.415187 beta-lactamase_2500_L197P,beta-lactamase_2500_197,TEM-1,beta-lactamase_2500,P62593,0.415236,NO,197,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.853,-4.068,3.215,,0.007,S,B,0.55,0.33,2.421,,60.14,HHP,-1.833,0.361275,0.00144602,0.415236 kka2_1:1_G88T,kka2_1:1_88,Kka2,kka2_1:1,P00552,0.415287,NO,88,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.689,-3.065,1.376,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.520039,0.00685559,0.415287 kka2_1:1_D180N,kka2_1:1_180,Kka2,kka2_1:1,P00552,0.415314,NO,180,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.416,-3.09,0.674,,1.03,S,a,0.75,1.5,1.534,,71.59,OAO,-2.02933,0.520039,0.00756412,0.415314 beta-lactamase_625_D231W,beta-lactamase_625_231,TEM-1,beta-lactamase_625,P62593,0.415351,NO,231,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.816,-5.545,4.729,,,E,B,0.75,-1.06,1.025,,65.38,HAB,-0.994,0.213352,0.00107395,0.415351 beta-lactamase_Y103K,beta-lactamase_103,TEM-1,beta-lactamase,P62593,0.415478,NO,103,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-1.33,-3.666,2.336,5.71734,0.613,S,l,2.55,1.21,5.721,,63.29,AHP,-1.48767,0.221079,0.00443048,0.415478 kka2_1:2_A14W,kka2_1:2_14,Kka2,kka2_1:2,P00552,0.415507,NO,14,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.837,-5.518,3.681,,0.728,G,A,0.46,0.7,0.36,,71.59,HHH,-1.82567,0.295029,0.00706614,0.415507 Pab1_I130Y,Pab1_130,Pab1,Pab1,P04147,0.415538,NO,130,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.212,-3.755,2.543,,,E,B,1.23,0.01,,,,HHB,-1.188,0.175299,0.000351112,0.415538 kka2_1:2_L232R,kka2_1:2_232,Kka2,kka2_1:2,P00552,0.415549,NO,232,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.514,-4.216,2.702,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.295029,0.00800103,0.415549 beta-lactamase_625_Y95A,beta-lactamase_625_95,TEM-1,beta-lactamase_625,P62593,0.415563,NO,95,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-1.715,-3.364,1.649,,0.122,,b,0.21,-0.37,3.355,,77.62,BHP,-2.16167,0.213352,0.00479449,0.415563 beta-lactamase_2500_R41G,beta-lactamase_2500_41,TEM-1,beta-lactamase_2500,P62593,0.415585,NO,41,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-0.942,-3.321,2.379,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.361275,0.00123327,0.415585 kka2_1:4_D190V,kka2_1:4_190,Kka2,kka2_1:4,P00552,0.415588,NO,190,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.708,-3.782,3.074,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.168804,0.00247989,0.415588 kka2_1:1_A255Y,kka2_1:1_255,Kka2,kka2_1:1,P00552,0.415612,NO,255,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.715,-3.332,1.617,,0.466,H,A,0.46,-0.52,0.946,,65.53,HHH,-1.71267,0.520039,0.0126809,0.415612 PSD95pdz3_H372F,PSD95pdz3_372,PSD95pdz3,PSD95pdz3,P31016,0.415626,NO,372,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-1.627,-3.524,1.897,5.5607,,,,,17.008,,,,PBA,-1.63033,0.0758425,0.00040301,0.415626 beta-lactamase_625_L219H,beta-lactamase_625_219,TEM-1,beta-lactamase_625,P62593,0.41563,NO,219,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.313,-4.957,3.644,,,I,A,0.55,-0.51,5.627,,74.48,HHB,-1.21533,0.213352,0.00664345,0.41563 beta-lactamase_2500_S266H,beta-lactamase_2500_266,TEM-1,beta-lactamase_2500,P62593,0.415717,NO,266,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.361275,0.0140785,0.415717 beta-lactamase_625_W208N,beta-lactamase_625_208,TEM-1,beta-lactamase_625,P62593,0.415786,NO,208,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-0.818,-4.348,3.53,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.213352,0.00126609,0.415786 beta-lactamase_625_S201P,beta-lactamase_625_201,TEM-1,beta-lactamase_625,P62593,0.415793,NO,201,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.183,-3.79,2.607,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.213352,0.00198815,0.415793 kka2_1:1_D156N,kka2_1:1_156,Kka2,kka2_1:1,P00552,0.415869,NO,156,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.696,-3.632,1.936,,0.884,T,A,0.75,1.87,1.044,,65.53,PAA,-1.765,0.520039,0.00926998,0.415869 kka2_1:8_A150P,kka2_1:8_150,Kka2,kka2_1:8,P00552,0.415908,NO,150,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.949,-3.782,2.833,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.100394,0.0045009,0.415908 kka2_1:8_A150P,kka2_1:8_150,Kka2,kka2_1:8,P00552,0.415908,NO,150,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.949,-3.782,2.833,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.100394,0.0045009,0.415908 kka2_1:2_D183A,kka2_1:2_183,Kka2,kka2_1:2,P00552,0.415922,NO,183,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.204,-3.349,2.145,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.295029,0.00426304,0.415922 kka2_1:1_A150T,kka2_1:1_150,Kka2,kka2_1:1,P00552,0.415923,NO,150,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.949,-3.378,2.429,,0.544,T,A,0.46,1.34,2.333,,63.26,AHO,-1.272,0.520039,0.0045009,0.415923 kka2_1:1_Y244F,kka2_1:1_244,Kka2,kka2_1:1,P00552,0.415977,NO,244,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-0.775,-2.97,2.195,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.520039,0.00453187,0.415977 kka2_1:8_L39Q,kka2_1:8_39,Kka2,kka2_1:8,P00552,0.416005,NO,39,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.223,-4.313,3.09,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.100394,0.00493618,0.416005 kka2_1:8_L39Q,kka2_1:8_39,Kka2,kka2_1:8,P00552,0.416005,NO,39,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.223,-4.313,3.09,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.100394,0.00493618,0.416005 beta-lactamase_156_A132Q,beta-lactamase_156_132,TEM-1,beta-lactamase_156,P62593,0.416068,NO,132,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.9,-3.943,3.043,,,H,A,0.46,-0.93,10.621,,64.69,PHH,-1.138,0.111618,0.000962524,0.416068 kka2_1:1_R44P,kka2_1:1_44,Kka2,kka2_1:1,P00552,0.416089,NO,44,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.062,-4.075,2.013,,0.487,S,B,1.2,-0.35,2.717,,71.59,OBO,-1.80767,0.520039,0.00745043,0.416089 beta-lactamase_2500_N274Q,beta-lactamase_2500_274,TEM-1,beta-lactamase_2500,P62593,0.416108,NO,274,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-2.082,-3.838,1.756,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.361275,0.0110418,0.416108 kka2_1:2_Y244R,kka2_1:2_244,Kka2,kka2_1:2,P00552,0.416126,NO,244,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-0.775,-3.961,3.186,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.295029,0.00453187,0.416126 kka2_1:2_A117Y,kka2_1:2_117,Kka2,kka2_1:2,P00552,0.416154,NO,117,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.828,-4.189,3.361,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.295029,0.00282984,0.416154 kka2_1:2_W24Q,kka2_1:2_24,Kka2,kka2_1:2,P00552,0.416163,NO,24,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-1.779,-4.365,2.586,,0.477,E,B,1.51,-0.21,2.666,,56.06,AHH,-2.24467,0.295029,0.00631564,0.416163 kka2_1:1_V36M,kka2_1:1_36,Kka2,kka2_1:1,P00552,0.416212,NO,36,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-0.898,-4.103,3.205,,0.292,E,B,0.44,0.21,0.278,,52.27,HHH,-1.484,0.520039,0.00245633,0.416212 beta-lactamase_625_R242M,beta-lactamase_625_242,TEM-1,beta-lactamase_625,P62593,0.416235,NO,242,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.213352,0.00452879,0.416235 beta-lactamase_625_V78Q,beta-lactamase_625_78,TEM-1,beta-lactamase_625,P62593,0.416306,NO,78,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.459,-4.26,2.801,,,H,A,0.44,-0.47,2.045,,63.64,HHH,-1.17833,0.213352,0.00492501,0.416306 beta-lactamase_156_W227C,beta-lactamase_156_227,TEM-1,beta-lactamase_156,P62593,0.416359,NO,227,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-0.982,-4.932,3.95,,0.272,,B,0.47,-0.29,2.533,,74.48,OHH,-1.595,0.111618,0.00226019,0.416359 kka2_1:1_I221M,kka2_1:1_221,Kka2,kka2_1:1,P00552,0.416388,NO,221,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.739,-4.064,2.325,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.520039,0.00945908,0.416388 kka2_1:1_H106Y,kka2_1:1_106,Kka2,kka2_1:1,P00552,0.416422,NO,106,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-3.13,-4.391,1.261,,1.065,.,a,0.17,-0.95,2.53,,71.59,PBH,-2.10433,0.520039,0.00730778,0.416422 kka2_1:2_E96F,kka2_1:2_96,Kka2,kka2_1:2,P00552,0.41653,NO,96,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.573,-4.257,1.684,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.295029,0.00369441,0.41653 beta-lactamase_156_I258E,beta-lactamase_156_258,TEM-1,beta-lactamase_156,P62593,0.416586,NO,258,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.111618,0.007931,0.416586 kka2_1:8_C131T,kka2_1:8_131,Kka2,kka2_1:8,P00552,0.416588,NO,131,C,T,CT,Special,Polar,5.07,5.6,0.53,149,121,119,-2,108.5,116.1,7.6,-0.831,-3.45,2.619,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.100394,0.00170814,0.416588 kka2_1:8_C131T,kka2_1:8_131,Kka2,kka2_1:8,P00552,0.416588,NO,131,C,T,CT,Special,Polar,5.07,5.6,0.53,149,121,119,-2,108.5,116.1,7.6,-0.831,-3.45,2.619,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.100394,0.00170814,0.416588 beta-lactamase_F64L,beta-lactamase_64,TEM-1,beta-lactamase,P62593,0.416731,NO,64,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-0.841,-2.908,2.067,5.70769,0.006,E,B,1.33,-0.95,,,,BHO,-0.892667,0.221079,0.000947691,0.416731 beta-lactamase_M115G,beta-lactamase_115,TEM-1,beta-lactamase,P62593,0.416731,NO,115,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.389,-3.632,2.243,4.89743,0.019,E,B,1.3,0.08,1.236,,69.58,OHP,-1.25433,0.221079,0.0034337,0.416731 beta-lactamase_2500_L197T,beta-lactamase_2500_197,TEM-1,beta-lactamase_2500,P62593,0.416751,NO,197,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.853,-3.419,2.566,,0.007,S,B,0.55,0.33,2.421,,60.14,HHP,-1.833,0.361275,0.00144602,0.416751 beta-lactamase_2500_D212W,beta-lactamase_2500_212,TEM-1,beta-lactamase_2500,P62593,0.416852,NO,212,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.624,-5.54,3.916,,0.037,,b,0.75,-0.58,12.482,,74.48,HAB,-1.77667,0.361275,0.00644302,0.416852 kka2_1:1_L174F,kka2_1:1_174,Kka2,kka2_1:1,P00552,0.416864,NO,174,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.952,-3.775,2.823,,,H,A,0.55,-0.31,13.276,13.276,51.89,BHB,-2.08533,0.520039,0.00438501,0.416864 beta-lactamase_2500_D83V,beta-lactamase_2500_83,TEM-1,beta-lactamase_2500,P62593,0.416869,NO,83,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.066,-3.762,2.696,,0.354,H,A,0.75,0.22,0.239,,48.95,HAH,-1.34733,0.361275,0.00205968,0.416869 kka2_1:2_P12M,kka2_1:2_12,Kka2,kka2_1:2,P00552,0.416905,NO,12,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.853,-4.703,3.85,,,.,B,0.52,1.25,0.261,,48.11,POH,-1.80767,0.295029,0.00500011,0.416905 kka2_1:8_C131N,kka2_1:8_131,Kka2,kka2_1:8,P00552,0.416912,NO,131,C,N,CN,Special,Polar,5.07,5.47157,0.401575,139,121,132,11,108.5,114.1,5.6,-0.831,-4.151,3.32,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.100394,0.00170814,0.416912 kka2_1:8_C131N,kka2_1:8_131,Kka2,kka2_1:8,P00552,0.416912,NO,131,C,N,CN,Special,Polar,5.07,5.47157,0.401575,139,121,132,11,108.5,114.1,5.6,-0.831,-4.151,3.32,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.100394,0.00170814,0.416912 kka2_1:1_G95N,kka2_1:1_95,Kka2,kka2_1:1,P00552,0.416941,NO,95,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-2.403,-2.561,0.158,,0.126,E,B,0.29,-0.74,7.822,,71.59,HOA,-2.198,0.520039,0.00743616,0.416941 kka2_1:1_K112L,kka2_1:1_112,Kka2,kka2_1:1,P00552,0.416943,NO,112,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-2.491,-2.229,-0.262,,0.076,H,A,2.34,-1.37,23.433,23.433,56.06,ABH,-2.00133,0.520039,0.00645389,0.416943 kka2_1:2_L223A,kka2_1:2_223,Kka2,kka2_1:2,P00552,0.416993,NO,223,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.861,-3.151,2.29,,,H,A,0.55,-1.24,0.266,,50,HHH,-0.854333,0.295029,0.00253574,0.416993 kka2_1:2_L223C,kka2_1:2_223,Kka2,kka2_1:2,P00552,0.416993,NO,223,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.861,-4.71,3.849,,,H,A,0.55,-1.24,0.266,,50,HHH,-0.854333,0.295029,0.00253574,0.416993 kka2_1:2_L223T,kka2_1:2_223,Kka2,kka2_1:2,P00552,0.416993,NO,223,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.861,-3.494,2.633,,,H,A,0.55,-1.24,0.266,,50,HHH,-0.854333,0.295029,0.00253574,0.416993 kka2_1:8_C209Q,kka2_1:8_209,Kka2,kka2_1:8,P00552,0.417053,NO,209,C,Q,CQ,Special,Polar,5.07,6.24429,1.17429,154,121,146,25,108.5,143.8,35.3,-0.906,-4.376,3.47,,,,a,1.5,-0.89,0.391,,19.32,AOO,-0.903,0.100394,0.00260862,0.417053 kka2_1:8_C209Q,kka2_1:8_209,Kka2,kka2_1:8,P00552,0.417053,NO,209,C,Q,CQ,Special,Polar,5.07,6.24429,1.17429,154,121,146,25,108.5,143.8,35.3,-0.906,-4.376,3.47,,,,a,1.5,-0.89,0.391,,19.32,AOO,-0.903,0.100394,0.00260862,0.417053 kka2_1:8_G205F,kka2_1:8_205,Kka2,kka2_1:8,P00552,0.41709,NO,205,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.596,-4.32,3.724,,,E,b,0.75,-1.05,,,,POH,-1.09933,0.100394,0.00221855,0.41709 kka2_1:8_G205F,kka2_1:8_205,Kka2,kka2_1:8,P00552,0.41709,NO,205,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.596,-4.32,3.724,,,E,b,0.75,-1.05,,,,POH,-1.09933,0.100394,0.00221855,0.41709 kka2_1:1_S114F,kka2_1:1_114,Kka2,kka2_1:1,P00552,0.417133,NO,114,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.527,-4.392,1.865,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.520039,0.00705262,0.417133 beta-lactamase_39_G249E,beta-lactamase_39_249,TEM-1,beta-lactamase_39,P62593,0.417228,NO,249,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.312,,,,0.256,S,B,0.23,0.04,30.841,30.841,72.73,HOO,-1.81367,0.0495842,0.00220169,0.417228 kka2_1:1_R211M,kka2_1:1_211,Kka2,kka2_1:1,P00552,0.417228,NO,211,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-0.899,-4.531,3.632,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.520039,0.00204888,0.417228 kka2_1:8_A215K,kka2_1:8_215,Kka2,kka2_1:8,P00552,0.417251,NO,215,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.968,-3.512,2.544,,0.039,E,B,1.04,-0.59,2.77,,50.38,HHA,-1.00467,0.100394,0.00529129,0.417251 kka2_1:8_A215K,kka2_1:8_215,Kka2,kka2_1:8,P00552,0.417251,NO,215,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.968,-3.512,2.544,,0.039,E,B,1.04,-0.59,2.77,,50.38,HHA,-1.00467,0.100394,0.00529129,0.417251 kka2_1:4_D159F,kka2_1:4_159,Kka2,kka2_1:4,P00552,0.417337,NO,159,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.82,-4.355,3.535,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.168804,0.0030485,0.417337 kka2_1:2_L259V,kka2_1:2_259,Kka2,kka2_1:2,P00552,0.417357,NO,259,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.088,-2.47,1.382,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.295029,0.0206964,0.417357 kka2_1:2_A137G,kka2_1:2_137,Kka2,kka2_1:2,P00552,0.417408,NO,137,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.156,-3.64,1.484,,0.029,H,A,0.46,0.34,1.323,,63.26,PHB,-2.559,0.295029,0.00515054,0.417408 hsp90_G584D,hsp90_584,hsp90,hsp90,P02829,0.417409,NO,584,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-2.511,-2.847,0,5.20094,0.414,S,b,0.84,0.33,,,,HOH,-3.32733,0.368192,0.000222939,0.417409 beta-lactamase_625_R273Y,beta-lactamase_625_273,TEM-1,beta-lactamase_625,P62593,0.417469,NO,273,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.314,-4.336,2.022,,0.564,H,A,1.2,1.57,1.455,,73.78,ABP,-1.841,0.213352,0.0077952,0.417469 beta-lactamase_625_P65Q,beta-lactamase_625_65,TEM-1,beta-lactamase_625,P62593,0.417563,NO,65,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.894,-3.954,3.06,,0.098,E,B,0.52,-0.62,0.3,,40.56,HOH,-1.03233,0.213352,0.00152776,0.417563 kka2_1:4_F263S,kka2_1:4_263,Kka2,kka2_1:4,P00552,0.417701,NO,263,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-0.911,-3.673,2.762,,0.006,G,A,0.58,-0.12,2.284,,45.83,AHH,-0.92,0.168804,0.0172454,0.417701 kka2_1:1_L165E,kka2_1:1_165,Kka2,kka2_1:1,P00552,0.417734,NO,165,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-2.453,-2.802,0.349,,0.299,,B,1.59,1.12,2.47,,64.39,OHH,-1.90967,0.520039,0.00801161,0.417734 beta-lactamase_2500_M115R,beta-lactamase_2500_115,TEM-1,beta-lactamase_2500,P62593,0.41778,NO,115,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.389,-2.862,1.473,,0.019,E,B,0.55,0.08,3.261,,69.58,OHP,-1.25433,0.361275,0.0034337,0.41778 kka2_1:8_R211E,kka2_1:8_211,Kka2,kka2_1:8,P00552,0.417804,NO,211,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-0.899,-3.317,2.418,,0.12,T,a,0.16,-0.39,0.615,,49.62,OBH,-0.966,0.100394,0.00204888,0.417804 kka2_1:8_R211E,kka2_1:8_211,Kka2,kka2_1:8,P00552,0.417804,NO,211,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-0.899,-3.317,2.418,,0.12,T,a,0.16,-0.39,0.615,,49.62,OBH,-0.966,0.100394,0.00204888,0.417804 beta-lactamase_625_M67E,beta-lactamase_625_67,TEM-1,beta-lactamase_625,P62593,0.418081,NO,67,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-2.231,-3.761,1.53,,0.006,G,P,0.55,-0.81,2.653,,65.03,HHP,-1.502,0.213352,0.00409753,0.418081 kka2_1:1_V214I,kka2_1:1_214,Kka2,kka2_1:1,P00552,0.418108,NO,214,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.261,-1.849,0.588,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.520039,0.00692782,0.418108 kka2_1:2_M148W,kka2_1:2_148,Kka2,kka2_1:2,P00552,0.418252,NO,148,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.847,-5.364,3.517,,0.268,H,A,1.59,0.71,1.439,,64.39,BHA,-1.65467,0.295029,0.00982664,0.418252 beta-lactamase_2500_L219A,beta-lactamase_2500_219,TEM-1,beta-lactamase_2500,P62593,0.418289,NO,219,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.313,-3.187,1.874,,,I,A,0.55,-0.51,35.994,35.994,74.48,HHB,-1.21533,0.361275,0.00664345,0.418289 beta-lactamase_625_A123Y,beta-lactamase_625_123,TEM-1,beta-lactamase_625,P62593,0.418292,NO,123,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.834,-4.16,3.326,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.213352,0.0010157,0.418292 kka2_1:1_D190N,kka2_1:1_190,Kka2,kka2_1:1,P00552,0.418336,NO,190,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.708,-3.251,2.543,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.520039,0.00247989,0.418336 beta-lactamase_2500_P143L,beta-lactamase_2500_143,TEM-1,beta-lactamase_2500,P62593,0.418408,NO,143,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.967,-2.577,1.61,,0.075,H,A,0.52,-0.37,0.479,,66.78,OOB,-1.354,0.361275,0.00114551,0.418408 kka2_1:4_A224R,kka2_1:4_224,Kka2,kka2_1:4,P00552,0.418408,NO,224,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.977,-3.85,2.873,,,H,A,0.46,-1.26,0.93,,63.64,HHP,-1.41033,0.168804,0.00352047,0.418408 kka2_1:1_M120A,kka2_1:1_120,Kka2,kka2_1:1,P00552,0.418427,NO,120,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-3.877,-3.104,-0.773,,,H,A,0.55,-0.42,2.259,,92.05,HHB,-2.16733,0.520039,0.00265808,0.418427 kka2_1:8_E262T,kka2_1:8_262,Kka2,kka2_1:8,P00552,0.418429,NO,262,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-0.829,-3.473,2.644,,0.059,G,A,1.52,-0.18,0.837,,42.42,AAH,-0.816,0.100394,0.0191586,0.418429 kka2_1:8_E262T,kka2_1:8_262,Kka2,kka2_1:8,P00552,0.418429,NO,262,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-0.829,-3.473,2.644,,0.059,G,A,1.52,-0.18,0.837,,42.42,AAH,-0.816,0.100394,0.0191586,0.418429 kka2_1:1_Y218F,kka2_1:1_218,Kka2,kka2_1:1,P00552,0.418441,NO,218,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-1.438,-2.611,1.173,,0.122,H,A,1.25,-0.69,3.059,,56.06,BHP,-1.17533,0.520039,0.0126098,0.418441 Pab1_L142P,Pab1_142,Pab1,Pab1,P04147,0.418469,NO,142,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.039,-3.922,2.883,,0.007,H,A,0.84,-0.65,,,,HHH,-1.487,0.175299,0.000335477,0.418469 beta-lactamase_2500_V72L,beta-lactamase_2500_72,TEM-1,beta-lactamase_2500,P62593,0.418526,NO,72,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.658,-2.403,0.745,,,H,A,0.44,-1.03,2.079,,65.73,BHH,-1.32167,0.361275,0.00501194,0.418526 beta-lactamase_W286E,beta-lactamase_286,TEM-1,beta-lactamase,P62593,0.41861,NO,286,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-1.111,-3.707,2.596,6.64456,0.492,,?,0.01,0.6,,,,BHX,-1.478,0.221079,,0.41861 beta-lactamase_625_Y44W,beta-lactamase_625_44,TEM-1,beta-lactamase_625,P62593,0.418661,NO,44,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-2.547,-5.1,2.553,,,E,B,0.21,-0.45,2.371,,73.78,OHH,-1.86267,0.213352,0.00426364,0.418661 kka2_1:2_Y22D,kka2_1:2_22,Kka2,kka2_1:2,P00552,0.418723,NO,22,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-1.583,-3.909,2.326,,0.122,.,B,0.21,-0.8,1.838,,65.53,OHA,-1.80333,0.295029,0.00598977,0.418723 kka2_1:1_A222Q,kka2_1:1_222,Kka2,kka2_1:1,P00552,0.418744,NO,222,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.725,-3.928,3.203,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.520039,0.00207657,0.418744 kka2_1:4_G30H,kka2_1:4_30,Kka2,kka2_1:4,P00552,0.418753,NO,30,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.596,-4.708,4.112,,0.54,S,g,0.29,3.76,,,,HOO,-1.51133,0.168804,0.00159208,0.418753 kka2_1:4_E169P,kka2_1:4_169,Kka2,kka2_1:4,P00552,0.418759,NO,169,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.996,-4.008,2.012,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.168804,0.00730086,0.418759 gb1_V280D,gb1_280,gb1,gb1,P06654,0.418802,NO,280,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.764,-3.741,1.977,,,,,,,0.874,,35.71,PHP,-1.63733,0.177985,0.00321577,0.418802 kka2_1:4_D227P,kka2_1:4_227,Kka2,kka2_1:4,P00552,0.418832,NO,227,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.758,-3.728,1.97,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.168804,0.00745029,0.418832 beta-lactamase_2500_L49P,beta-lactamase_2500_49,TEM-1,beta-lactamase_2500,P62593,0.418872,NO,49,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.897,-2.49,0.593,,0.131,T,A,0.55,0.04,6.681,,64.69,AHP,-1.99233,0.361275,0.00401477,0.418872 beta-lactamase_2500_T126W,beta-lactamase_2500_126,TEM-1,beta-lactamase_2500,P62593,0.418884,NO,126,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.122,-5.243,4.121,,0.05,H,A,0.22,-0.05,0.817,,44.41,HPH,-1.60467,0.361275,0.00244552,0.418884 kka2_1:2_M197T,kka2_1:2_197,Kka2,kka2_1:2,P00552,0.418977,NO,197,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.707,-2.639,0.932,,0.121,E,B,0.55,-1.19,2.097,,65.53,HHH,-1.847,0.295029,0.00921295,0.418977 kka2_1:4_R211M,kka2_1:4_211,Kka2,kka2_1:4,P00552,0.419031,NO,211,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-0.899,-4.531,3.632,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.168804,0.00204888,0.419031 beta-lactamase_2500_P105M,beta-lactamase_2500_105,TEM-1,beta-lactamase_2500,P62593,0.419059,NO,105,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.813,-4.702,3.889,,0.226,T,A,0.52,0.8,3.1,,63.29,POH,-1.01533,0.361275,0.0011981,0.419059 kka2_1:8_A215Q,kka2_1:8_215,Kka2,kka2_1:8,P00552,0.419104,NO,215,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.968,-3.954,2.986,,0.039,E,B,1.04,-0.59,2.77,,50.38,HHA,-1.00467,0.100394,0.00529129,0.419104 kka2_1:8_A215Q,kka2_1:8_215,Kka2,kka2_1:8,P00552,0.419104,NO,215,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.968,-3.954,2.986,,0.039,E,B,1.04,-0.59,2.77,,50.38,HHA,-1.00467,0.100394,0.00529129,0.419104 kka2_1:8_G245F,kka2_1:8_245,Kka2,kka2_1:8,P00552,0.419104,NO,245,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.812,-4.364,3.552,,0.655,T,g,0.75,0.03,1.148,,65.53,HOH,-1.19833,0.100394,0.00683899,0.419104 kka2_1:8_G245F,kka2_1:8_245,Kka2,kka2_1:8,P00552,0.419104,NO,245,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.812,-4.364,3.552,,0.655,T,g,0.75,0.03,1.148,,65.53,HOH,-1.19833,0.100394,0.00683899,0.419104 kka2_1:8_D208M,kka2_1:8_208,Kka2,kka2_1:8,P00552,0.419105,NO,208,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.708,-4.958,4.25,,0.36,,l,0.29,-1.01,,,,HAO,-0.929667,0.100394,0.00212588,0.419105 kka2_1:8_D208M,kka2_1:8_208,Kka2,kka2_1:8,P00552,0.419105,NO,208,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.708,-4.958,4.25,,0.36,,l,0.29,-1.01,,,,HAO,-0.929667,0.100394,0.00212588,0.419105 beta-lactamase_625_I93K,beta-lactamase_625_93,TEM-1,beta-lactamase_625,P62593,0.419303,NO,93,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.401,-3.873,2.472,,0.128,E,B,0.48,0.44,1.524,,67.83,BHB,-1.873,0.213352,0.00527066,0.419303 beta-lactamase_2500_N168Q,beta-lactamase_2500_168,TEM-1,beta-lactamase_2500,P62593,0.41932,NO,168,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-1.029,-3.749,2.72,,0.113,G,A,0.61,-0.4,2.9,,44.41,HPA,-1.13233,0.361275,0.00288667,0.41932 Ubiquitin_A46P,Ubiquitin_46,Uba1,Ubiquitin,P0CG48,0.419355,NO,46,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.77,-3.969,2.199,5.38761,0.398,T,L,2.34,-0.8,6.506,,51.09,HHO,-1.505,0.205827,0.000581142,0.419355 Ubiquitin_F4S,Ubiquitin_4,Uba1,Ubiquitin,P0CG48,0.419355,NO,4,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.534,-2.372,0.838,4.77459,0.059,E,B,,-0.46,,,,HHH,-1.504,0.205827,0.000805043,0.419355 Ubiquitin_G10R,Ubiquitin_10,Uba1,Ubiquitin,P0CG48,0.419355,NO,10,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.396,-2.619,1.223,5.29806,0.115,S,l,,0.2,,,,POB,-1.38633,0.205827,0.000748953,0.419355 Ubiquitin_H68E,Ubiquitin_68,Uba1,Ubiquitin,P0CG48,0.419355,NO,68,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-1.869,-3.55,1.681,4.81902,0.194,E,B,0.72,-1.02,21.325,21.325,65.11,HBH,-1.583,0.205827,0.000925438,0.419355 kka2_1:8_I115P,kka2_1:8_115,Kka2,kka2_1:8,P00552,0.419393,NO,115,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.606,-4.209,2.603,,0.105,H,A,1.52,-1.18,4.064,,65.53,PHH,-2.205,0.100394,0.00836567,0.419393 kka2_1:8_I115P,kka2_1:8_115,Kka2,kka2_1:8,P00552,0.419393,NO,115,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.606,-4.209,2.603,,0.105,H,A,1.52,-1.18,4.064,,65.53,PHH,-2.205,0.100394,0.00836567,0.419393 kka2_1:2_I221F,kka2_1:2_221,Kka2,kka2_1:2,P00552,0.419411,NO,221,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.739,-3.76,2.021,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.295029,0.00945908,0.419411 beta-lactamase_156_E164D,beta-lactamase_156_164,TEM-1,beta-lactamase_156,P62593,0.419418,NO,164,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-0.948,-2.949,2.001,,0.011,T,B,1.04,-0.4,3.445,,64.69,HAO,-1.388,0.111618,0.00137286,0.419418 kka2_1:2_T146P,kka2_1:2_146,Kka2,kka2_1:2,P00552,0.419462,NO,146,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.978,-4.011,1.033,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.295029,0.00606474,0.419462 kka2_1:8_I196E,kka2_1:8_196,Kka2,kka2_1:8,P00552,0.419538,NO,196,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-2.115,-4.03,1.915,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.100394,0.0107273,0.419538 kka2_1:8_I196E,kka2_1:8_196,Kka2,kka2_1:8,P00552,0.419538,NO,196,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-2.115,-4.03,1.915,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.100394,0.0107273,0.419538 beta-lactamase_E119F,beta-lactamase_119,TEM-1,beta-lactamase,P62593,0.41955,NO,119,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.412,-4.398,2.986,5.33349,0.358,H,A,1.52,0.51,1.983,,63.99,BAH,-1.623,0.221079,0.00386966,0.41955 beta-lactamase_2500_F58E,beta-lactamase_2500_58,TEM-1,beta-lactamase_2500,P62593,0.419616,NO,58,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-2.914,-3.579,0.665,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.361275,0.00523369,0.419616 beta-lactamase_156_C121P,beta-lactamase_156_121,TEM-1,beta-lactamase_156,P62593,0.419677,NO,121,C,P,CP,Special,Special,5.07,6.3,1.23,169,121,115,-6,108.5,112.7,4.2,-0.953,-4.102,3.149,,,H,A,0.46,-0.81,1.136,,63.29,HOP,-1.46767,0.111618,0.000744322,0.419677 kka2_1:2_Q136F,kka2_1:2_136,Kka2,kka2_1:2,P00552,0.41968,NO,136,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-3.021,-4.399,1.378,,0.331,,b,0.4,0.96,2.726,,92.05,BPH,-2.16933,0.295029,0.00624149,0.41968 beta-lactamase_2500_I93A,beta-lactamase_2500_93,TEM-1,beta-lactamase_2500,P62593,0.419697,NO,93,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.401,-3.13,1.729,,0.128,E,B,0.48,0.44,19.374,19.374,67.83,BHB,-1.873,0.361275,0.00527066,0.419697 beta-lactamase_2500_D174G,beta-lactamase_2500_174,TEM-1,beta-lactamase_2500,P62593,0.419708,NO,174,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.738,-3.133,2.395,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.361275,0.00125633,0.419708 beta-lactamase_2500_P224L,beta-lactamase_2500_224,TEM-1,beta-lactamase_2500,P62593,0.419733,NO,224,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.893,-3.582,2.689,,0.383,,B,0.52,-0.3,2.666,,74.48,HOH,-1.26433,0.361275,0.00189564,0.419733 kka2_1:4_R226T,kka2_1:4_226,Kka2,kka2_1:4,P00552,0.419812,NO,226,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.392,-3.626,2.234,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.168804,0.0108032,0.419812 beta-lactamase_2500_G265F,beta-lactamase_2500_265,TEM-1,beta-lactamase_2500,P62593,0.419902,NO,265,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.361275,0.00811926,0.419902 beta-lactamase_156_S233V,beta-lactamase_156_233,TEM-1,beta-lactamase_156,P62593,0.419943,NO,233,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.886,-3.357,1.471,,0.016,E,B,0.27,-1.01,4.111,,77.62,BPO,-1.17267,0.111618,0.00311415,0.419943 beta-lactamase_625_I45G,beta-lactamase_625_45,TEM-1,beta-lactamase_625,P62593,0.419991,NO,45,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-2.421,-3.565,1.144,,,E,B,0.48,-0.3,3.642,,77.62,HHA,-2.30267,0.213352,0.00452842,0.419991 beta-lactamase_39_L120K,beta-lactamase_39_120,TEM-1,beta-lactamase_39,P62593,0.420004,NO,120,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.044,-3.668,2.624,,,H,A,0.55,-1.13,22.254,22.254,64.69,AHO,-1.13633,0.0495842,0.00143563,0.420004 beta-lactamase_2500_L28C,beta-lactamase_2500_28,TEM-1,beta-lactamase_2500,P62593,0.42005,NO,28,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.579,-4.763,3.184,,0.277,H,A,0.55,-0.16,2.716,,93.01,PHH,-2.11333,0.361275,0.00359321,0.42005 kka2_1:2_F264C,kka2_1:2_264,Kka2,kka2_1:2,P00552,0.42005,NO,264,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.02,-4.944,3.924,,0.296,.,?,0.58,0.02,2.303,,71.59,HHNA,-0.9655,0.295029,,0.42005 kka2_1:1_R253M,kka2_1:1_253,Kka2,kka2_1:1,P00552,0.420087,NO,253,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.356,-4.619,3.263,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.520039,0.0144195,0.420087 kka2_1:1_G210L,kka2_1:1_210,Kka2,kka2_1:1,P00552,0.420098,NO,210,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.095,-3.634,2.539,,0.103,T,A,0.29,-0.62,14.483,14.483,50,OOB,-0.966667,0.520039,0.00598378,0.420098 kka2_1:8_L94D,kka2_1:8_94,Kka2,kka2_1:8,P00552,0.420142,NO,94,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.618,-4.088,2.47,,0.058,E,B,1.59,-0.52,2.197,,56.06,HHO,-1.612,0.100394,0.00520888,0.420142 kka2_1:8_L94D,kka2_1:8_94,Kka2,kka2_1:8,P00552,0.420142,NO,94,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.618,-4.088,2.47,,0.058,E,B,1.59,-0.52,2.197,,56.06,HHO,-1.612,0.100394,0.00520888,0.420142 kka2_1:2_L170G,kka2_1:2_170,Kka2,kka2_1:2,P00552,0.420163,NO,170,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.28,-3.713,2.433,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.295029,0.00730791,0.420163 kka2_1:2_L170Y,kka2_1:2_170,Kka2,kka2_1:2,P00552,0.420163,NO,170,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.28,-4.115,2.835,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.295029,0.00730791,0.420163 kka2_1:2_G233S,kka2_1:2_233,Kka2,kka2_1:2,P00552,0.42025,NO,233,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.748,-3.234,2.486,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.295029,0.00232366,0.42025 kka2_1:4_Y244N,kka2_1:4_244,Kka2,kka2_1:4,P00552,0.420357,NO,244,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-0.775,-3.926,3.151,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.168804,0.00453187,0.420357 kka2_1:1_R202P,kka2_1:1_202,Kka2,kka2_1:1,P00552,0.420389,NO,202,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.761,-4.079,2.318,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.520039,0.00696498,0.420389 beta-lactamase_2500_I93T,beta-lactamase_2500_93,TEM-1,beta-lactamase_2500,P62593,0.42047,NO,93,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.401,-2.729,1.328,,0.128,E,B,0.48,0.44,19.374,19.374,67.83,BHB,-1.873,0.361275,0.00527066,0.42047 beta-lactamase_2500_A132V,beta-lactamase_2500_132,TEM-1,beta-lactamase_2500,P62593,0.420474,NO,132,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.9,-2.46,1.56,,,H,A,0.46,-0.93,8.408,,64.69,PHH,-1.138,0.361275,0.000962524,0.420474 kka2_1:2_Q26C,kka2_1:2_26,Kka2,kka2_1:2,P00552,0.420526,NO,26,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.18,-5.205,3.025,,0.448,E,B,0.4,0.44,5.022,,92.05,HPP,-2.11167,0.295029,0.00708962,0.420526 PSD95pdz3_A347M,PSD95pdz3_347,PSD95pdz3,PSD95pdz3,P31016,0.420637,NO,347,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.307,-4.162,2.855,4.89689,,,,,15.176,,,,OHA,-1.269,0.0758425,0.00074525,0.420637 beta-lactamase_2500_P105N,beta-lactamase_2500_105,TEM-1,beta-lactamase_2500,P62593,0.420649,NO,105,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.813,-3.82,3.007,,0.226,T,A,0.52,0.8,3.1,,63.29,POH,-1.01533,0.361275,0.0011981,0.420649 kka2_1:2_V113R,kka2_1:2_113,Kka2,kka2_1:2,P00552,0.420657,NO,113,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.233,-4.233,3,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.295029,0.00650191,0.420657 kka2_1:8_L123H,kka2_1:8_123,Kka2,kka2_1:8,P00552,0.42067,NO,123,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.888,-4.956,4.068,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.100394,0.00325188,0.42067 kka2_1:8_L123H,kka2_1:8_123,Kka2,kka2_1:8,P00552,0.42067,NO,123,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.888,-4.956,4.068,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.100394,0.00325188,0.42067 kka2_1:1_R38I,kka2_1:1_38,Kka2,kka2_1:1,P00552,0.42069,NO,38,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.207,-3.515,2.308,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.520039,0.00372499,0.42069 beta-lactamase_2500_G141T,beta-lactamase_2500_141,TEM-1,beta-lactamase_2500,P62593,0.420723,NO,141,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.828,-3.647,2.819,,0.575,T,l,0.29,-0.28,1.493,,64.69,HOO,-1.08933,0.361275,0.0012419,0.420723 beta-lactamase_R220P,beta-lactamase_220,TEM-1,beta-lactamase,P62593,0.420739,NO,220,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-0.942,-3.877,2.935,5.65995,0.295,I,A,0.68,-0.76,2.164,,74.48,HBP,-1.33633,0.221079,0.00232421,0.420739 kka2_1:1_R140T,kka2_1:1_140,Kka2,kka2_1:1,P00552,0.420827,NO,140,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.351,-2.806,1.455,,0.12,H,A,1.2,0.2,11.345,11.345,53.03,BBH,-1.885,0.520039,0.00430167,0.420827 beta-lactamase_2500_L120C,beta-lactamase_2500_120,TEM-1,beta-lactamase_2500,P62593,0.420861,NO,120,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.044,-4.81,3.766,,,H,A,0.55,-1.13,2.48,,64.69,AHO,-1.13633,0.361275,0.00143563,0.420861 kka2_1:1_A166C,kka2_1:1_166,Kka2,kka2_1:1,P00552,0.420973,NO,166,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.407,-5.041,2.634,,0.534,.,B,0.46,1.03,1.147,,71.59,HHO,-2.421,0.520039,0.00799912,0.420973 kka2_1:8_L67W,kka2_1:8_67,Kka2,kka2_1:8,P00552,0.420992,NO,67,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.741,-5.126,4.385,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.100394,0.00102787,0.420992 kka2_1:8_L67W,kka2_1:8_67,Kka2,kka2_1:8,P00552,0.420992,NO,67,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.741,-5.126,4.385,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.100394,0.00102787,0.420992 kka2_1:4_R38F,kka2_1:4_38,Kka2,kka2_1:4,P00552,0.421021,NO,38,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.207,-4.103,2.896,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.168804,0.00372499,0.421021 beta-lactamase_2500_T107M,beta-lactamase_2500_107,TEM-1,beta-lactamase_2500,P62593,0.421024,NO,107,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.117,-4.531,3.414,,,G,A,0.22,-0.06,2.686,,67.83,HPA,-1.265,0.361275,0.00239347,0.421024 kka2_1:2_A110P,kka2_1:2_110,Kka2,kka2_1:2,P00552,0.421053,NO,110,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.064,-3.089,1.025,,0.175,H,A,0.46,-1.19,23.237,23.237,71.59,OHA,-1.91867,0.295029,0.00759851,0.421053 kka2_1:2_P128M,kka2_1:2_128,Kka2,kka2_1:2,P00552,0.42113,NO,128,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.922,-4.47,2.548,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.295029,0.00774689,0.42113 beta-lactamase_0_T187K,beta-lactamase_0_187,TEM-1,beta-lactamase_0,P62593,0.421134,NO,187,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.401,-3.578,2.177,,0.007,H,A,0.22,-1.19,3.259,,67.48,PPH,-1.69633,0.0500837,0.00491782,0.421134 beta-lactamase_156_A123R,beta-lactamase_156_123,TEM-1,beta-lactamase_156,P62593,0.421199,NO,123,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.834,-3.776,2.942,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.111618,0.0010157,0.421199 beta-lactamase_625_P181L,beta-lactamase_625_181,TEM-1,beta-lactamase_625,P62593,0.421247,NO,181,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.813,-3.546,2.733,,,H,A,0.52,-1.14,1.797,,61.54,HOH,-1.795,0.213352,0.000703122,0.421247 beta-lactamase_2500_R41D,beta-lactamase_2500_41,TEM-1,beta-lactamase_2500,P62593,0.42133,NO,41,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-0.942,-3.657,2.715,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.361275,0.00123327,0.42133 beta-lactamase_N134E,beta-lactamase_134,TEM-1,beta-lactamase,P62593,0.421334,NO,134,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-0.879,-3.212,2.333,5.07245,0.138,H,A,0.09,-0.6,1.441,,53.15,HPH,-1.02233,0.221079,0.000644786,0.421334 beta-lactamase_2500_I285Q,beta-lactamase_2500_285,TEM-1,beta-lactamase_2500,P62593,0.421344,NO,285,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.361275,0.101555,0.421344 beta-lactamase_625_T147Y,beta-lactamase_625_147,TEM-1,beta-lactamase_625,P62593,0.421348,NO,147,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.149,-4.243,3.094,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.213352,0.00226017,0.421348 beta-lactamase_2500_D155E,beta-lactamase_2500_155,TEM-1,beta-lactamase_2500,P62593,0.42141,NO,155,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.889,-2.299,1.41,,0.049,,B,0.75,-0.9,2.386,,64.69,OAB,-1.62267,0.361275,0.00135315,0.42141 beta-lactamase_2500_N130D,beta-lactamase_2500_130,TEM-1,beta-lactamase_2500,P62593,0.421479,NO,130,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-0.798,-3.019,2.221,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.361275,0.000683376,0.421479 kka2_1:1_P128S,kka2_1:1_128,Kka2,kka2_1:1,P00552,0.421518,NO,128,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.922,-3.672,1.75,,0.316,G,A,0.52,0.4,2.178,,56.06,AOH,-1.64733,0.520039,0.00774689,0.421518 kka2_1:1_Q163P,kka2_1:1_163,Kka2,kka2_1:1,P00552,0.421541,NO,163,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.162,-4.062,1.9,,0.58,T,B,0.64,1.85,2.779,,64.02,BPO,-1.78333,0.520039,0.00719507,0.421541 kka2_1:2_D101H,kka2_1:2_101,Kka2,kka2_1:2,P00552,0.421622,NO,101,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.028,-4.537,3.509,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.295029,0.00423361,0.421622 kka2_1:2_W69H,kka2_1:2_69,Kka2,kka2_1:2,P00552,0.421624,NO,69,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-0.859,-4.594,3.735,,0.164,H,A,0.47,0.15,5.074,,38.64,PHH,-1.49967,0.295029,0.0012874,0.421624 kka2_1:2_A119R,kka2_1:2_119,Kka2,kka2_1:2,P00552,0.421629,NO,119,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.073,-3.886,2.813,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.295029,0.00441074,0.421629 kka2_1:4_L92F,kka2_1:4_92,Kka2,kka2_1:4,P00552,0.421672,NO,92,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.893,-3.727,2.834,,0.007,E,B,0.55,-0.19,1.447,,63.26,HHH,-0.962,0.168804,0.00307177,0.421672 kka2_1:2_E96P,kka2_1:2_96,Kka2,kka2_1:2,P00552,0.421677,NO,96,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.573,-3.855,1.282,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.295029,0.00369441,0.421677 kka2_1:1_P45D,kka2_1:1_45,Kka2,kka2_1:1,P00552,0.421835,NO,45,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.774,-3.026,1.252,,0.669,.,B,0.52,-0.76,4.882,,71.59,BOH,-2.152,0.520039,0.00590481,0.421835 beta-lactamase_L120Q,beta-lactamase_120,TEM-1,beta-lactamase,P62593,0.421993,NO,120,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.044,-4.124,3.08,5.11974,,H,A,1.3,-1.13,1.988,,64.69,AHO,-1.13633,0.221079,0.00143563,0.421993 beta-lactamase_L160D,beta-lactamase_160,TEM-1,beta-lactamase,P62593,0.421993,NO,160,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.977,-4.122,3.145,5.32068,0.022,,B,1.75,-0.6,0.895,,44.41,BHA,-0.936,0.221079,0.00193775,0.421993 kka2_1:1_A64R,kka2_1:1_64,Kka2,kka2_1:1,P00552,0.422017,NO,64,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.496,-4.086,2.59,,0.039,H,A,0.46,-0.57,1.175,,56.06,AHH,-1.334,0.520039,0.00705578,0.422017 kka2_1:2_Y257S,kka2_1:2_257,Kka2,kka2_1:2,P00552,0.422017,NO,257,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-1.064,-3.698,2.634,,0.022,H,A,0.21,-0.88,0.833,,52.65,HHB,-1.39333,0.295029,0.0148191,0.422017 kka2_1:1_S32Y,kka2_1:1_32,Kka2,kka2_1:1,P00552,0.422043,NO,32,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-0.804,-4.191,3.387,,0.768,S,b,0.27,3.75,,,,OPA,-1.74533,0.520039,0.00149998,0.422043 kka2_1:1_L92W,kka2_1:1_92,Kka2,kka2_1:1,P00552,0.422077,NO,92,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.893,-5.185,4.292,,0.007,E,B,0.55,-0.19,1.447,,63.26,HHH,-0.962,0.520039,0.00307177,0.422077 kka2_1:4_I207T,kka2_1:4_207,Kka2,kka2_1:4,P00552,0.422112,NO,207,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.175,-3.466,2.291,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.168804,0.00611824,0.422112 kka2_1:1_W91D,kka2_1:1_91,Kka2,kka2_1:1,P00552,0.422135,NO,91,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-1.178,-4.116,2.938,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.520039,0.00358653,0.422135 beta-lactamase_N168K,beta-lactamase_168,TEM-1,beta-lactamase,P62593,0.422168,NO,168,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-1.029,-3.307,2.278,5.42128,0.113,G,A,0.09,-0.4,1.211,,44.41,HPA,-1.13233,0.221079,0.00288667,0.422168 beta-lactamase_156_Y95K,beta-lactamase_156_95,TEM-1,beta-lactamase_156,P62593,0.422182,NO,95,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-1.715,-3.936,2.221,,0.122,,b,0.21,-0.37,2.341,,77.62,BHP,-2.16167,0.111618,0.00479449,0.422182 beta-lactamase_625_L219Q,beta-lactamase_625_219,TEM-1,beta-lactamase_625,P62593,0.4222,NO,219,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.313,-4.292,2.979,,,I,A,0.55,-0.51,5.627,,74.48,HHB,-1.21533,0.213352,0.00664345,0.4222 kka2_1:8_I228M,kka2_1:8_228,Kka2,kka2_1:8,P00552,0.422266,NO,228,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.142,-4.08,2.938,,,H,A,1.52,-1.2,1.521,,71.59,AHH,-1.54633,0.100394,0.00458834,0.422266 kka2_1:8_I228M,kka2_1:8_228,Kka2,kka2_1:8,P00552,0.422266,NO,228,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.142,-4.08,2.938,,,H,A,1.52,-1.2,1.521,,71.59,AHH,-1.54633,0.100394,0.00458834,0.422266 kka2_1:8_L92R,kka2_1:8_92,Kka2,kka2_1:8,P00552,0.42227,NO,92,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.893,-4.021,3.128,,0.007,E,B,1.59,-0.19,1.719,,63.26,HHH,-0.962,0.100394,0.00307177,0.42227 kka2_1:8_L92R,kka2_1:8_92,Kka2,kka2_1:8,P00552,0.42227,NO,92,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.893,-4.021,3.128,,0.007,E,B,1.59,-0.19,1.719,,63.26,HHH,-0.962,0.100394,0.00307177,0.42227 kka2_1:1_D220V,kka2_1:1_220,Kka2,kka2_1:1,P00552,0.422276,NO,220,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.787,-2.698,1.911,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.520039,0.00158066,0.422276 kka2_1:1_S105A,kka2_1:1_105,Kka2,kka2_1:1,P00552,0.422353,NO,105,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.945,-1.746,-0.199,,0.056,S,B,0.27,-1.04,3.442,,65.53,PPB,-2.17033,0.520039,0.00847233,0.422353 kka2_1:4_I207N,kka2_1:4_207,Kka2,kka2_1:4,P00552,0.422376,NO,207,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.175,-4.238,3.063,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.168804,0.00611824,0.422376 hsp90_E590P,hsp90_590,hsp90,hsp90,P02829,0.422488,NO,590,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.818,-3.033,0,4.65049,0.021,H,A,,0.03,,,,HAO,-3.338,0.368192,0.000222939,0.422488 beta-lactamase_T69L,beta-lactamase_69,TEM-1,beta-lactamase,P62593,0.422552,NO,69,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-0.973,-3.213,2.24,5.16042,,G,A,0.69,-1.24,0.505,,93.01,PPH,-1.01833,0.221079,0.00127498,0.422552 beta-lactamase_625_I258G,beta-lactamase_625_258,TEM-1,beta-lactamase_625,P62593,0.422592,NO,258,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.213352,0.007931,0.422592 kka2_1:1_Q100C,kka2_1:1_100,Kka2,kka2_1:1,P00552,0.422626,NO,100,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.77,-3.712,0.942,,0.646,E,B,0.4,-0.79,15.116,15.116,71.59,OPA,-1.46467,0.520039,0.0066405,0.422626 kka2_1:2_R140H,kka2_1:2_140,Kka2,kka2_1:2,P00552,0.422813,NO,140,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.351,-4.514,3.163,,0.12,H,A,1.2,0.2,0.352,,53.03,BBH,-1.885,0.295029,0.00430167,0.422813 beta-lactamase_R220Y,beta-lactamase_220,TEM-1,beta-lactamase,P62593,0.422828,NO,220,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-0.942,-4.188,3.246,5.65995,0.295,I,A,0.68,-0.76,2.164,,74.48,HBP,-1.33633,0.221079,0.00232421,0.422828 kka2_1:2_M120W,kka2_1:2_120,Kka2,kka2_1:2,P00552,0.422929,NO,120,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-3.877,-5.169,1.292,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.295029,0.00265808,0.422929 beta-lactamase_S201D,beta-lactamase_201,TEM-1,beta-lactamase,P62593,0.422935,NO,201,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.183,-3.453,2.27,4.85496,0.064,H,A,0.77,-0.07,4.045,,64.69,HPB,-1.451,0.221079,0.00198815,0.422935 beta-lactamase_156_V259N,beta-lactamase_156_259,TEM-1,beta-lactamase_156,P62593,0.42307,NO,259,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.111618,0.0070773,0.42307 beta-lactamase_625_D231R,beta-lactamase_625_231,TEM-1,beta-lactamase_625,P62593,0.423098,NO,231,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.816,-3.896,3.08,,,E,B,0.75,-1.06,1.025,,65.38,HAB,-0.994,0.213352,0.00107395,0.423098 kka2_1:1_E161V,kka2_1:1_161,Kka2,kka2_1:1,P00552,0.423102,NO,161,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.581,-2.903,1.322,,0.829,G,A,1.04,2.24,1.612,,92.05,AAB,-1.861,0.520039,0.00760103,0.423102 kka2_1:4_I221F,kka2_1:4_221,Kka2,kka2_1:4,P00552,0.423119,NO,221,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.739,-3.76,2.021,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.168804,0.00945908,0.423119 kka2_1:8_E262L,kka2_1:8_262,Kka2,kka2_1:8,P00552,0.423128,NO,262,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-0.829,-3.61,2.781,,0.059,G,A,1.52,-0.18,0.837,,42.42,AAH,-0.816,0.100394,0.0191586,0.423128 kka2_1:8_E262L,kka2_1:8_262,Kka2,kka2_1:8,P00552,0.423128,NO,262,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-0.829,-3.61,2.781,,0.059,G,A,1.52,-0.18,0.837,,42.42,AAH,-0.816,0.100394,0.0191586,0.423128 kka2_1:2_A215V,kka2_1:2_215,Kka2,kka2_1:2,P00552,0.423133,NO,215,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.968,-3.282,2.314,,0.039,E,B,0.46,-0.59,2.137,,50.38,HHA,-1.00467,0.295029,0.00529129,0.423133 kka2_1:1_D159V,kka2_1:1_159,Kka2,kka2_1:1,P00552,0.423155,NO,159,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.82,-3.816,2.996,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.520039,0.0030485,0.423155 PSD95pdz3_G324R,PSD95pdz3_324,PSD95pdz3,PSD95pdz3,P31016,0.423217,NO,324,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.008,-3.615,2.607,4.98881,,,,,10.4525,,,,HOH,-1.293,0.0758425,0.00103462,0.423217 kka2_1:8_F256H,kka2_1:8_256,Kka2,kka2_1:8,P00552,0.423223,NO,256,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.49,-4.32,2.83,,,H,A,1.62,-0.78,1.713,,53.03,HHH,-1.423,0.100394,0.0132841,0.423223 kka2_1:8_F256H,kka2_1:8_256,Kka2,kka2_1:8,P00552,0.423223,NO,256,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.49,-4.32,2.83,,,H,A,1.62,-0.78,1.713,,53.03,HHH,-1.423,0.100394,0.0132841,0.423223 kka2_1:8_L39E,kka2_1:8_39,Kka2,kka2_1:8,P00552,0.423223,NO,39,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.223,-3.962,2.739,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.100394,0.00493618,0.423223 kka2_1:8_L39E,kka2_1:8_39,Kka2,kka2_1:8,P00552,0.423223,NO,39,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.223,-3.962,2.739,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.100394,0.00493618,0.423223 Pab1_I196N,Pab1_196,Pab1,Pab1,P04147,0.423227,NO,196,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.795,-4.016,2.221,,,,,,,2.013,,80.59,AHH,-1.44667,0.175299,0.0016933,0.423227 beta-lactamase_2500_L49G,beta-lactamase_2500_49,TEM-1,beta-lactamase_2500,P62593,0.423311,NO,49,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.897,-3.581,1.684,,0.131,T,A,0.55,0.04,6.681,,64.69,AHP,-1.99233,0.361275,0.00401477,0.423311 beta-lactamase_2500_I285R,beta-lactamase_2500_285,TEM-1,beta-lactamase_2500,P62593,0.423407,NO,285,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.361275,0.101555,0.423407 kka2_1:1_P98G,kka2_1:1_98,Kka2,kka2_1:1,P00552,0.423412,NO,98,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.526,-3.498,1.972,,0.391,S,B,0.52,-0.65,1.521,,63.26,HOO,-1.19167,0.520039,0.00622754,0.423412 kka2_1:4_L102D,kka2_1:4_102,Kka2,kka2_1:4,P00552,0.423416,NO,102,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.804,-4.17,3.366,,,T,A,0.55,-1.17,0.65,,42.42,AHH,-1.398,0.168804,0.00201332,0.423416 beta-lactamase_39_L146P,beta-lactamase_39_146,TEM-1,beta-lactamase_39,P62593,0.423422,NO,146,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.462,-4.216,2.754,,0.007,H,A,0.55,-0.56,1.953,,64.69,AHP,-1.656,0.0495842,0.00474542,0.423422 beta-lactamase_625_W208H,beta-lactamase_625_208,TEM-1,beta-lactamase_625,P62593,0.423548,NO,208,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-0.818,-4.68,3.862,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.213352,0.00126609,0.423548 kka2_1:2_C192R,kka2_1:2_192,Kka2,kka2_1:2,P00552,0.423548,NO,192,C,R,CR,Special,PositiveCharge,5.07,6.34148,1.27148,180,121,174,53,108.5,173.4,64.9,-1.067,-4.134,3.067,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.295029,0.00485428,0.423548 kka2_1:1_P45L,kka2_1:1_45,Kka2,kka2_1:1,P00552,0.423552,NO,45,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.774,-3.048,1.274,,0.669,.,B,0.52,-0.76,4.882,,71.59,BOH,-2.152,0.520039,0.00590481,0.423552 kka2_1:1_C131R,kka2_1:1_131,Kka2,kka2_1:1,P00552,0.423576,NO,131,C,R,CR,Special,PositiveCharge,5.07,6.34148,1.27148,180,121,174,53,108.5,173.4,64.9,-0.831,-4.186,3.355,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.520039,0.00170814,0.423576 WW_domain_R203D,WW_domain_203,Yap65,WW_domain,P46937,0.423589,NO,203,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.539,-3.476,1.937,5.41321,,,,,,1.9,,70.04,OBO,-1.4695,0.153962,0.00172433,0.423589 kka2_1:8_R66Y,kka2_1:8_66,Kka2,kka2_1:8,P00552,0.423616,NO,66,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-0.922,-4.225,3.303,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.100394,0.00161025,0.423616 kka2_1:8_R66Y,kka2_1:8_66,Kka2,kka2_1:8,P00552,0.423616,NO,66,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-0.922,-4.225,3.303,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.100394,0.00161025,0.423616 beta-lactamase_2500_T187R,beta-lactamase_2500_187,TEM-1,beta-lactamase_2500,P62593,0.423636,NO,187,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.401,-3.885,2.484,,0.007,H,A,0.22,-1.19,3.91,,67.48,PPH,-1.69633,0.361275,0.00491782,0.423636 beta-lactamase_2500_V117A,beta-lactamase_2500_117,TEM-1,beta-lactamase_2500,P62593,0.423645,NO,117,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.53,-3.142,1.612,,,H,A,0.44,-0.34,1.23,,65.03,PHB,-1.741,0.361275,0.00467906,0.423645 beta-lactamase_2500_G114H,beta-lactamase_2500_114,TEM-1,beta-lactamase_2500,P62593,0.423727,NO,114,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.094,-4.665,3.571,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.361275,0.00224919,0.423727 kka2_1:1_D250N,kka2_1:1_250,Kka2,kka2_1:1,P00552,0.423763,NO,250,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.015,-2.686,1.671,,0.274,.,b,0.75,-0.46,4.177,,51.89,OAP,-1.83933,0.520039,0.0177103,0.423763 kka2_1:2_T72W,kka2_1:2_72,Kka2,kka2_1:2,P00552,0.42382,NO,72,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.38,-5.516,3.136,,0.784,H,A,0.82,0.29,6.463,,65.53,HPP,-2.238,0.295029,0.00750756,0.42382 beta-lactamase_2500_S201V,beta-lactamase_2500_201,TEM-1,beta-lactamase_2500,P62593,0.423881,NO,201,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.183,-3.482,2.299,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.361275,0.00198815,0.423881 kka2_1:2_L107H,kka2_1:2_107,Kka2,kka2_1:2,P00552,0.423897,NO,107,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.238,-4.994,3.756,,0.197,,B,1.59,-1.1,2.68,,71.59,BHH,-2.143,0.295029,0.00561937,0.423897 beta-lactamase_2500_E35M,beta-lactamase_2500_35,TEM-1,beta-lactamase_2500,P62593,0.423939,NO,35,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-0.869,-4.754,3.885,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.361275,0.00174441,0.423939 kka2_1:1_P167S,kka2_1:1_167,Kka2,kka2_1:1,P00552,0.423977,NO,167,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-2.403,-2.618,0.215,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.520039,0.00543203,0.423977 beta-lactamase_A235R,beta-lactamase_235,TEM-1,beta-lactamase,P62593,0.424,NO,235,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.266,-3.887,2.621,4.83024,0.32,E,B,0.52,-0.86,1.344,,50,OHO,-0.89,0.221079,0.00493474,0.424 kka2_1:1_T225F,kka2_1:1_225,Kka2,kka2_1:1,P00552,0.424018,NO,225,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.393,-4.221,1.828,,0.036,H,A,0.22,-1.22,4.554,,63.64,HPB,-1.58733,0.520039,0.0113598,0.424018 beta-lactamase_625_K286P,beta-lactamase_625_286,TEM-1,beta-lactamase_625,P62593,0.424075,NO,286,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.213352,,0.424075 kka2_1:4_I221P,kka2_1:4_221,Kka2,kka2_1:4,P00552,0.424127,NO,221,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.739,-4.232,2.493,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.168804,0.00945908,0.424127 kka2_1:1_L223I,kka2_1:1_223,Kka2,kka2_1:1,P00552,0.424254,NO,223,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.861,-2.071,1.21,,,H,A,0.55,-1.24,1.268,,50,HHH,-0.854333,0.520039,0.00253574,0.424254 kka2_1:1_G88E,kka2_1:1_88,Kka2,kka2_1:1,P00552,0.424292,NO,88,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.689,-2.331,0.642,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.520039,0.00685559,0.424292 beta-lactamase_2500_A40E,beta-lactamase_2500_40,TEM-1,beta-lactamase_2500,P62593,0.424306,NO,40,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.402,-3.641,2.239,,0.155,S,B,0.46,0.21,0.953,,73.78,OHB,-1.40267,0.361275,0.00490026,0.424306 kka2_1:4_H135I,kka2_1:4_135,Kka2,kka2_1:4,P00552,0.424312,NO,135,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-1.331,-3.976,2.645,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.168804,0.00532566,0.424312 kka2_1:4_S32Y,kka2_1:4_32,Kka2,kka2_1:4,P00552,0.424312,NO,32,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-0.804,-4.191,3.387,,0.768,S,b,0.27,3.75,,,,OPA,-1.74533,0.168804,0.00149998,0.424312 beta-lactamase_2500_R59A,beta-lactamase_2500_59,TEM-1,beta-lactamase_2500,P62593,0.424319,NO,59,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.345,-3.163,1.818,,0.329,S,L,1.2,-0.09,3.719,,73.08,HBO,-2.24267,0.361275,0.00318082,0.424319 kka2_1:1_W69T,kka2_1:1_69,Kka2,kka2_1:1,P00552,0.424323,NO,69,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-0.859,-3.698,2.839,,0.164,H,A,0.47,0.15,5.074,,38.64,PHH,-1.49967,0.520039,0.0012874,0.424323 kka2_1:2_G99H,kka2_1:2_99,Kka2,kka2_1:2,P00552,0.424345,NO,99,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.596,-4.708,4.112,,0.368,S,g,0.29,-0.87,,,,OOP,-1.63067,0.295029,0.00186055,0.424345 Pab1_A182E,Pab1_182,Pab1,Pab1,P04147,0.424378,NO,182,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.013,-3.257,2.244,,,H,A,0.17,0.79,,,,AHH,-1.36067,0.175299,0.000289034,0.424378 beta-lactamase_0_M115Q,beta-lactamase_0_115,TEM-1,beta-lactamase_0,P62593,0.42441,NO,115,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.389,-3.893,2.504,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.0500837,0.0034337,0.42441 kka2_1:8_L60K,kka2_1:8_60,Kka2,kka2_1:8,P00552,0.424458,NO,60,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.997,-3.814,2.817,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.100394,0.00262176,0.424458 kka2_1:8_L60K,kka2_1:8_60,Kka2,kka2_1:8,P00552,0.424458,NO,60,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.997,-3.814,2.817,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.100394,0.00262176,0.424458 kka2_1:1_A247V,kka2_1:1_247,Kka2,kka2_1:1,P00552,0.42448,NO,247,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.459,-2.971,0.512,,1.01,S,A,0.46,0.65,7.731,7.731,92.05,HHH,-2.197,0.520039,0.0102428,0.42448 beta-lactamase_625_L219K,beta-lactamase_625_219,TEM-1,beta-lactamase_625,P62593,0.424489,NO,219,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.313,-3.875,2.562,,,I,A,0.55,-0.51,5.627,,74.48,HHB,-1.21533,0.213352,0.00664345,0.424489 beta-lactamase_2500_G142H,beta-lactamase_2500_142,TEM-1,beta-lactamase_2500,P62593,0.424595,NO,142,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.707,-4.678,3.971,,0.034,,p,0.29,-0.64,1.883,,64.69,OOO,-0.834,0.361275,0.00060149,0.424595 beta-lactamase_2500_V31T,beta-lactamase_2500_31,TEM-1,beta-lactamase_2500,P62593,0.424597,NO,31,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.822,-2.805,0.983,,,H,A,0.44,-0.46,0.955,,73.78,BHB,-2.03767,0.361275,0.00478065,0.424597 gb1_V265E,gb1_265,gb1,gb1,P06654,0.424654,NO,265,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.843,-3.469,1.626,,,,,,,0.402,,11.83,OHA,-1.64567,0.177985,0.00360613,0.424654 kka2_1:2_V75S,kka2_1:2_75,Kka2,kka2_1:2,P00552,0.424768,NO,75,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-2.06,-3.699,1.639,,0.042,.,B,0.44,-0.2,2.815,,71.59,OHO,-1.563,0.295029,0.00693733,0.424768 kka2_1:4_M148D,kka2_1:4_148,Kka2,kka2_1:4,P00552,0.42479,NO,148,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.847,-4.109,2.262,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.168804,0.00982664,0.42479 kka2_1:1_S114M,kka2_1:1_114,Kka2,kka2_1:1,P00552,0.424792,NO,114,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.527,-3.615,1.088,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.520039,0.00705262,0.424792 beta-lactamase_156_W208G,beta-lactamase_156_208,TEM-1,beta-lactamase_156,P62593,0.424865,NO,208,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-0.818,-3.358,2.54,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.111618,0.00126609,0.424865 kka2_1:1_A65F,kka2_1:1_65,Kka2,kka2_1:1,P00552,0.424883,NO,65,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.744,-4.347,2.603,,0.437,H,A,0.46,-0.39,3.012,,63.64,HHB,-1.38733,0.520039,0.00709258,0.424883 kka2_1:8_V186W,kka2_1:8_186,Kka2,kka2_1:8,P00552,0.424932,NO,186,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.011,-5.309,4.298,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.100394,0.00409703,0.424932 kka2_1:8_V186W,kka2_1:8_186,Kka2,kka2_1:8,P00552,0.424932,NO,186,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.011,-5.309,4.298,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.100394,0.00409703,0.424932 kka2_1:1_K50V,kka2_1:1_50,Kka2,kka2_1:1,P00552,0.424976,NO,50,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-0.833,-3.601,2.768,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.520039,0.00138626,0.424976 beta-lactamase_2500_E62L,beta-lactamase_2500_62,TEM-1,beta-lactamase_2500,P62593,0.424977,NO,62,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.193,-3.66,2.467,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.361275,0.00264802,0.424977 kka2_1:2_S104Y,kka2_1:2_104,Kka2,kka2_1:2,P00552,0.425027,NO,104,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.436,-4.278,2.842,,0.536,T,A,0.27,-1.11,5.49,,63.64,HPP,-1.91433,0.295029,0.00555207,0.425027 kka2_1:8_V49Q,kka2_1:8_49,Kka2,kka2_1:8,P00552,0.425027,NO,49,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.614,-4.261,2.647,,,E,B,1.48,-0.77,1.31,,64.39,HHB,-1.3,0.100394,0.00615685,0.425027 kka2_1:8_V49Q,kka2_1:8_49,Kka2,kka2_1:8,P00552,0.425027,NO,49,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.614,-4.261,2.647,,,E,B,1.48,-0.77,1.31,,64.39,HHB,-1.3,0.100394,0.00615685,0.425027 beta-lactamase_2500_P143N,beta-lactamase_2500_143,TEM-1,beta-lactamase_2500,P62593,0.425039,NO,143,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.967,-3.954,2.987,,0.075,H,A,0.52,-0.37,0.479,,66.78,OOB,-1.354,0.361275,0.00114551,0.425039 beta-lactamase_2500_R162C,beta-lactamase_2500_162,TEM-1,beta-lactamase_2500,P62593,0.425091,NO,162,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.016,-5.08,4.064,,0.124,S,B,1.2,-0.37,6.199,,64.69,ABH,-1.25,0.361275,0.000561334,0.425091 kka2_1:1_E235T,kka2_1:1_235,Kka2,kka2_1:1,P00552,0.425108,NO,235,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.955,-3.009,1.054,,0.631,H,A,1.52,0.12,8.521,,65.53,OAH,-2.07267,0.520039,0.0102806,0.425108 beta-lactamase_2500_D231L,beta-lactamase_2500_231,TEM-1,beta-lactamase_2500,P62593,0.425198,NO,231,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.816,-3.806,2.99,,,E,B,0.75,-1.06,0.319,,65.38,HAB,-0.994,0.361275,0.00107395,0.425198 kka2_1:4_M120A,kka2_1:4_120,Kka2,kka2_1:4,P00552,0.425222,NO,120,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-3.877,-3.104,-0.773,,,H,A,0.55,-0.42,2.259,,92.05,HHB,-2.16733,0.168804,0.00265808,0.425222 beta-lactamase_2500_M115K,beta-lactamase_2500_115,TEM-1,beta-lactamase_2500,P62593,0.425232,NO,115,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.389,-3.553,2.164,,0.019,E,B,0.55,0.08,3.261,,69.58,OHP,-1.25433,0.361275,0.0034337,0.425232 beta-lactamase_625_E87K,beta-lactamase_625_87,TEM-1,beta-lactamase_625,P62593,0.425277,NO,87,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.421,-2.715,1.294,,0.048,,B,1.04,0.92,17.923,17.923,64.69,PAP,-1.969,0.213352,0.00337888,0.425277 Pab1_V171F,Pab1_171,Pab1,Pab1,P04147,0.425288,NO,171,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.113,-3.659,2.546,,0.008,E,b,0.23,-0.34,,,,HHB,-1.19733,0.175299,0.000298662,0.425288 kka2_1:1_I141L,kka2_1:1_141,Kka2,kka2_1:1,P00552,0.425316,NO,141,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.495,-1.454,-0.041,,0.068,H,A,0.48,-0.01,7.546,7.546,92.05,BHA,-1.689,0.520039,0.00744745,0.425316 kka2_1:1_G181Q,kka2_1:1_181,Kka2,kka2_1:1,P00552,0.425332,NO,181,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-2.698,-2.961,0.263,,0.379,S,B,0.75,0.78,15.356,15.356,71.59,AOA,-2.21,0.520039,0.00728319,0.425332 kka2_1:8_E182I,kka2_1:8_182,Kka2,kka2_1:8,P00552,0.425405,NO,182,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.516,-4.087,2.571,,0.326,,B,1.52,0.75,2.568,,65.53,OAA,-1.806,0.100394,0.00641548,0.425405 kka2_1:8_E182I,kka2_1:8_182,Kka2,kka2_1:8,P00552,0.425405,NO,182,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.516,-4.087,2.571,,0.326,,B,1.52,0.75,2.568,,65.53,OAA,-1.806,0.100394,0.00641548,0.425405 kka2_1:2_V75Y,kka2_1:2_75,Kka2,kka2_1:2,P00552,0.425421,NO,75,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-2.06,-4.054,1.994,,0.042,.,B,0.44,-0.2,2.815,,71.59,OHO,-1.563,0.295029,0.00693733,0.425421 beta-lactamase_625_M115Y,beta-lactamase_625_115,TEM-1,beta-lactamase_625,P62593,0.425453,NO,115,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.389,-3.961,2.572,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.213352,0.0034337,0.425453 beta-lactamase_2500_L135C,beta-lactamase_2500_135,TEM-1,beta-lactamase_2500,P62593,0.4255,NO,135,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.002,-4.691,3.689,,0.117,H,A,0.55,-0.58,0.795,,43.71,PHH,-1.03767,0.361275,0.00244423,0.4255 kka2_1:2_F263V,kka2_1:2_263,Kka2,kka2_1:2,P00552,0.425544,NO,263,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-0.911,-3.287,2.376,,0.006,G,A,1.62,-0.12,5.275,,45.83,AHH,-0.92,0.295029,0.0172454,0.425544 kka2_1:4_D127Y,kka2_1:4_127,Kka2,kka2_1:4,P00552,0.425568,NO,127,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.364,-4.502,3.138,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.168804,0.00660501,0.425568 beta-lactamase_39_M209N,beta-lactamase_39_209,TEM-1,beta-lactamase_39,P62593,0.425593,NO,209,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.442,-4.092,2.65,,,H,A,0.55,-0.97,1.167,,64.69,HHA,-1.52633,0.0495842,0.00625021,0.425593 kka2_1:4_A229P,kka2_1:4_229,Kka2,kka2_1:4,P00552,0.425697,NO,229,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.739,-3.997,2.258,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.168804,0.00942138,0.425697 PSD95pdz3_A347R,PSD95pdz3_347,PSD95pdz3,PSD95pdz3,P31016,0.425703,NO,347,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.307,-3.39,2.083,4.89689,,,,,15.176,,,,OHA,-1.269,0.0758425,0.00074525,0.425703 kka2_1:4_Y244R,kka2_1:4_244,Kka2,kka2_1:4,P00552,0.425748,NO,244,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-0.775,-3.961,3.186,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.168804,0.00453187,0.425748 kka2_1:4_L170R,kka2_1:4_170,Kka2,kka2_1:4,P00552,0.425778,NO,170,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.28,-4.103,2.823,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.168804,0.00730791,0.425778 beta-lactamase_2500_G281I,beta-lactamase_2500_281,TEM-1,beta-lactamase_2500,P62593,0.425783,NO,281,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.361275,0.0406482,0.425783 beta-lactamase_625_E119V,beta-lactamase_625_119,TEM-1,beta-lactamase_625,P62593,0.4258,NO,119,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.412,-3.661,2.249,,0.358,H,A,1.04,0.51,1.034,,63.99,BAH,-1.623,0.213352,0.00386966,0.4258 beta-lactamase_A133V,beta-lactamase_133,TEM-1,beta-lactamase,P62593,0.425807,NO,133,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.186,-3.341,2.155,4.86423,,H,A,0.55,-0.86,2.649,,67.83,HHP,-0.988333,0.221079,0.00468022,0.425807 kka2_1:1_A35D,kka2_1:1_35,Kka2,kka2_1:1,P00552,0.425833,NO,35,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.127,-2.127,0,,0.107,E,B,0.46,1.05,8.405,8.405,71.59,HHH,-1.31767,0.520039,0.00630016,0.425833 kka2_1:1_A144G,kka2_1:1_144,Kka2,kka2_1:1,P00552,0.425861,NO,144,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.859,-3.076,2.217,,,H,A,0.46,0.21,0.842,,52.65,BHB,-1.72933,0.520039,0.00231095,0.425861 kka2_1:1_A35L,kka2_1:1_35,Kka2,kka2_1:1,P00552,0.425874,NO,35,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.127,-3.045,0.918,,0.107,E,B,0.46,1.05,8.405,8.405,71.59,HHH,-1.31767,0.520039,0.00630016,0.425874 kka2_1:1_C77F,kka2_1:1_77,Kka2,kka2_1:1,P00552,0.425875,NO,77,C,F,CF,Special,Hydrophobic,5.07,3.32051,-1.74949,205,121,165,44,108.5,189.9,81.4,-1.477,-4.235,2.758,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.520039,0.00441216,0.425875 kka2_1:2_D227V,kka2_1:2_227,Kka2,kka2_1:2,P00552,0.425892,NO,227,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.758,-3.661,1.903,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.295029,0.00745029,0.425892 kka2_1:8_D220E,kka2_1:8_220,Kka2,kka2_1:8,P00552,0.425972,NO,220,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.787,-2.878,2.091,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.100394,0.00158066,0.425972 kka2_1:8_D220E,kka2_1:8_220,Kka2,kka2_1:8,P00552,0.425972,NO,220,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.787,-2.878,2.091,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.100394,0.00158066,0.425972 kka2_1:8_L184D,kka2_1:8_184,Kka2,kka2_1:8,P00552,0.425972,NO,184,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.496,-4.1,2.604,,0.489,E,B,0.55,-0.06,4.495,,63.26,AHH,-1.24833,0.100394,0.00518742,0.425972 kka2_1:8_L184D,kka2_1:8_184,Kka2,kka2_1:8,P00552,0.425972,NO,184,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.496,-4.1,2.604,,0.489,E,B,0.55,-0.06,4.495,,63.26,AHH,-1.24833,0.100394,0.00518742,0.425972 kka2_1:1_A248W,kka2_1:1_248,Kka2,kka2_1:1,P00552,0.426024,NO,248,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.124,-5.601,3.477,,0.825,S,b,0.46,0.46,24.72,24.72,92.05,HHO,-2.15,0.520039,0.0125484,0.426024 beta-lactamase_0_E195C,beta-lactamase_0_195,TEM-1,beta-lactamase_0,P62593,0.426087,NO,195,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.186,-5.238,3.052,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.0500837,0.00496565,0.426087 kka2_1:1_D183S,kka2_1:1_183,Kka2,kka2_1:1,P00552,0.426133,NO,183,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.204,-3.317,2.113,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.520039,0.00426304,0.426133 beta-lactamase_2500_L223N,beta-lactamase_2500_223,TEM-1,beta-lactamase_2500,P62593,0.426297,NO,223,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.055,-4.1,3.045,,0.27,,B,0.55,0.09,1.334,,74.48,HHO,-1.35033,0.361275,0.00372793,0.426297 kka2_1:8_K50L,kka2_1:8_50,Kka2,kka2_1:8,P00552,0.426314,NO,50,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-0.833,-3.41,2.577,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.100394,0.00138626,0.426314 kka2_1:8_K50L,kka2_1:8_50,Kka2,kka2_1:8,P00552,0.426314,NO,50,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-0.833,-3.41,2.577,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.100394,0.00138626,0.426314 beta-lactamase_R241F,beta-lactamase_241,TEM-1,beta-lactamase,P62593,0.426337,NO,241,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.433,-4.274,2.841,5.02621,0.094,E,B,0.68,-0.16,1.327,,50,PBO,-1.42967,0.221079,0.00452736,0.426337 kka2_1:1_T146F,kka2_1:1_146,Kka2,kka2_1:1,P00552,0.426382,NO,146,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.978,-4.333,1.355,,0.281,H,A,0.82,0.78,2.105,,92.05,BPB,-1.96833,0.520039,0.00606474,0.426382 kka2_1:1_E63G,kka2_1:1_63,Kka2,kka2_1:1,P00552,0.426384,NO,63,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-0.762,-3.386,2.624,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.520039,0.00118399,0.426384 kka2_1:1_R143Q,kka2_1:1_143,Kka2,kka2_1:1,P00552,0.426417,NO,143,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.525,-3.295,0.77,,0.325,H,A,0.16,1.22,3.6,,65.53,ABH,-1.86833,0.520039,0.00662247,0.426417 kka2_1:1_L123P,kka2_1:1_123,Kka2,kka2_1:1,P00552,0.426427,NO,123,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.888,-4.155,3.267,,0.007,H,A,0.55,-0.4,1.447,,48.86,BHB,-1.301,0.520039,0.00325188,0.426427 kka2_1:4_D159P,kka2_1:4_159,Kka2,kka2_1:4,P00552,0.426467,NO,159,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.82,-3.747,2.927,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.168804,0.0030485,0.426467 kka2_1:4_I196S,kka2_1:4_196,Kka2,kka2_1:4,P00552,0.426493,NO,196,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-2.115,-3.786,1.671,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.168804,0.0107273,0.426493 beta-lactamase_625_I140K,beta-lactamase_625_140,TEM-1,beta-lactamase_625,P62593,0.426497,NO,140,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.733,-3.879,2.146,,0.128,H,A,0.48,0.41,1.628,,73.08,PHO,-1.48733,0.213352,0.00597777,0.426497 kka2_1:1_Q100V,kka2_1:1_100,Kka2,kka2_1:1,P00552,0.426568,NO,100,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.77,-2.771,0.001,,0.646,E,B,0.4,-0.79,15.116,15.116,71.59,OPA,-1.46467,0.520039,0.0066405,0.426568 kka2_1:4_A144K,kka2_1:4_144,Kka2,kka2_1:4,P00552,0.426596,NO,144,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.859,-3.568,2.709,,,H,A,0.46,0.21,6.844,,52.65,BHB,-1.72933,0.168804,0.00231095,0.426596 beta-lactamase_0_M115F,beta-lactamase_0_115,TEM-1,beta-lactamase_0,P62593,0.426619,NO,115,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.389,-2.82,1.431,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.0500837,0.0034337,0.426619 kka2_1:2_H135F,kka2_1:2_135,Kka2,kka2_1:2,P00552,0.42669,NO,135,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-1.331,-4.11,2.779,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.295029,0.00532566,0.42669 kka2_1:1_V49C,kka2_1:1_49,Kka2,kka2_1:1,P00552,0.426701,NO,49,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.614,-4.784,3.17,,,E,B,0.44,-0.77,3.665,3.665,64.39,HHB,-1.3,0.520039,0.00615685,0.426701 beta-lactamase_P20I,beta-lactamase_20,TEM-1,beta-lactamase,P62593,0.426711,NO,20,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.74,-3.615,1.875,,,,,,,0.368,,67.83,HOH,-1.765,0.221079,0.00235322,0.426711 beta-lactamase_2500_Y103Q,beta-lactamase_2500_103,TEM-1,beta-lactamase_2500,P62593,0.426758,NO,103,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-1.33,-2.924,1.594,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.361275,0.00443048,0.426758 kka2_1:4_D183Y,kka2_1:4_183,Kka2,kka2_1:4,P00552,0.426765,NO,183,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.204,-4.387,3.183,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.168804,0.00426304,0.426765 kka2_1:4_D216L,kka2_1:4_216,Kka2,kka2_1:4,P00552,0.42677,NO,216,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.785,-3.835,3.05,,0.018,E,B,0.75,-0.51,0.112,,19.32,HAB,-0.970333,0.168804,0.00229969,0.42677 PSD95pdz3_A376M,PSD95pdz3_376,PSD95pdz3,PSD95pdz3,P31016,0.426781,NO,376,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.307,-4.162,2.855,4.72134,,,,,17.108,,,,HHH,-1.49567,0.0758425,0.000341232,0.426781 kka2_1:1_G10K,kka2_1:1_10,Kka2,kka2_1:1,P00552,0.426803,NO,10,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.921,-2.49,0.569,,,,,,,1.862,,71.59,HOP,-2.10733,0.520039,0.00289233,0.426803 kka2_1:1_S105P,kka2_1:1_105,Kka2,kka2_1:1,P00552,0.426806,NO,105,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.945,-3.155,1.21,,0.056,S,B,0.27,-1.04,3.442,,65.53,PPB,-2.17033,0.520039,0.00847233,0.426806 beta-lactamase_G236E,beta-lactamase_236,TEM-1,beta-lactamase,P62593,0.426825,NO,236,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.784,-3.634,2.85,4.7915,0.241,,b,0.23,-0.59,1.883,,64.69,HOA,-1.36933,0.221079,0.00162372,0.426825 beta-lactamase_625_T27F,beta-lactamase_625_27,TEM-1,beta-lactamase_625,P62593,0.426885,NO,27,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.905,-2.968,1.063,,0.007,H,A,0.22,-0.37,3.72,,93.01,APH,-1.97933,0.213352,0.00306559,0.426885 kka2_1:1_A108C,kka2_1:1_108,Kka2,kka2_1:1,P00552,0.426951,NO,108,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.061,-5.089,3.028,,0.243,.,B,0.46,-1.34,3.156,,71.59,HHO,-1.57033,0.520039,0.00751209,0.426951 beta-lactamase_2500_L223Q,beta-lactamase_2500_223,TEM-1,beta-lactamase_2500,P62593,0.426954,NO,223,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.055,-4.184,3.129,,0.27,,B,0.55,0.09,1.334,,74.48,HHO,-1.35033,0.361275,0.00372793,0.426954 beta-lactamase_2500_A246M,beta-lactamase_2500_246,TEM-1,beta-lactamase_2500,P62593,0.42703,NO,246,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.121,-2.882,0.761,,0.01,E,B,0.46,-1.01,0.753,,73.78,HHH,-1.55633,0.361275,0.00569458,0.42703 kka2_1:2_R66H,kka2_1:2_66,Kka2,kka2_1:2,P00552,0.427039,NO,66,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-0.922,-4.322,3.4,,0.103,H,A,1.2,-0.2,2.659,,46.21,HBH,-1.13567,0.295029,0.00161025,0.427039 beta-lactamase_156_M209S,beta-lactamase_156_209,TEM-1,beta-lactamase_156,P62593,0.427047,NO,209,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.442,-3.579,2.137,,,H,A,0.55,-0.97,1.066,,64.69,HHA,-1.52633,0.111618,0.00625021,0.427047 Pab1_I130P,Pab1_130,Pab1,Pab1,P04147,0.42705,NO,130,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.212,-3.922,2.71,,,E,B,1.23,0.01,,,,HHB,-1.188,0.175299,0.000351112,0.42705 kka2_1:4_H124I,kka2_1:4_124,Kka2,kka2_1:4,P00552,0.427091,NO,124,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-0.84,-4.039,3.199,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.168804,0.00211296,0.427091 kka2_1:8_Y257S,kka2_1:8_257,Kka2,kka2_1:8,P00552,0.427103,NO,257,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-1.064,-3.698,2.634,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.100394,0.0148191,0.427103 kka2_1:8_Y257S,kka2_1:8_257,Kka2,kka2_1:8,P00552,0.427103,NO,257,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-1.064,-3.698,2.634,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.100394,0.0148191,0.427103 kka2_1:1_L232F,kka2_1:1_232,Kka2,kka2_1:1,P00552,0.427104,NO,232,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.514,-2.061,0.547,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.520039,0.00800103,0.427104 PSD95pdz3_G345P,PSD95pdz3_345,PSD95pdz3,PSD95pdz3,P31016,0.427136,NO,345,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.008,-3.561,2.553,4.32868,,,,,13.165,,,,OOO,-1.084,0.0758425,0.000771806,0.427136 kka2_1:8_A119Y,kka2_1:8_119,Kka2,kka2_1:8,P00552,0.427181,NO,119,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.073,-4.266,3.193,,0.019,H,A,0.46,-0.57,1.511,,71.59,AHH,-2.34,0.100394,0.00441074,0.427181 kka2_1:8_A119Y,kka2_1:8_119,Kka2,kka2_1:8,P00552,0.427181,NO,119,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.073,-4.266,3.193,,0.019,H,A,0.46,-0.57,1.511,,71.59,AHH,-2.34,0.100394,0.00441074,0.427181 beta-lactamase_156_N168K,beta-lactamase_156_168,TEM-1,beta-lactamase_156,P62593,0.427188,NO,168,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-1.029,-3.307,2.278,,0.113,G,A,0.61,-0.4,1.014,,44.41,HPA,-1.13233,0.111618,0.00288667,0.427188 beta-lactamase_625_V78S,beta-lactamase_625_78,TEM-1,beta-lactamase_625,P62593,0.427225,NO,78,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.459,-3.701,2.242,,,H,A,0.44,-0.47,2.045,,63.64,HHH,-1.17833,0.213352,0.00492501,0.427225 kka2_1:1_T187V,kka2_1:1_187,Kka2,kka2_1:1,P00552,0.427256,NO,187,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.273,-3.25,1.977,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.520039,0.00693073,0.427256 beta-lactamase_2500_G240N,beta-lactamase_2500_240,TEM-1,beta-lactamase_2500,P62593,0.427261,NO,240,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.361275,0.00591201,0.427261 beta-lactamase_C121Q,beta-lactamase_121,TEM-1,beta-lactamase,P62593,0.427324,NO,121,C,Q,CQ,Special,Polar,5.07,6.24429,1.17429,154,121,146,25,108.5,143.8,35.3,-0.953,-4.222,3.269,5.12205,,H,A,2.8,-0.81,7.644,,63.29,HOP,-1.46767,0.221079,0.000744322,0.427324 kka2_1:2_L158P,kka2_1:2_158,Kka2,kka2_1:2,P00552,0.427332,NO,158,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.947,-2.892,0.945,,0.095,,B,1.59,0.77,7.588,,63.64,AHA,-1.25333,0.295029,0.00529068,0.427332 beta-lactamase_625_R59W,beta-lactamase_625_59,TEM-1,beta-lactamase_625,P62593,0.427363,NO,59,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.345,-5.421,4.076,,0.329,S,L,1.2,-0.09,2.995,,73.08,HBO,-2.24267,0.213352,0.00318082,0.427363 kka2_1:1_E262Q,kka2_1:1_262,Kka2,kka2_1:1,P00552,0.427384,NO,262,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-0.829,-2.552,1.723,,0.059,G,A,1.04,-0.18,0.837,,42.42,AAH,-0.816,0.520039,0.0191586,0.427384 kka2_1:1_E262C,kka2_1:1_262,Kka2,kka2_1:1,P00552,0.427405,NO,262,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-0.829,-5.339,4.51,,0.059,G,A,1.04,-0.18,0.837,,42.42,AAH,-0.816,0.520039,0.0191586,0.427405 kka2_1:1_E262W,kka2_1:1_262,Kka2,kka2_1:1,P00552,0.427405,NO,262,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-0.829,-5.349,4.52,,0.059,G,A,1.04,-0.18,0.837,,42.42,AAH,-0.816,0.520039,0.0191586,0.427405 kka2_1:4_R66E,kka2_1:4_66,Kka2,kka2_1:4,P00552,0.427417,NO,66,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-0.922,-3.242,2.32,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.168804,0.00161025,0.427417 Ubiquitin_A46E,Ubiquitin_46,Uba1,Ubiquitin,P0CG48,0.427419,NO,46,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.77,-2.829,1.059,5.38761,0.398,T,L,2.34,-0.8,6.506,,51.09,HHO,-1.505,0.205827,0.000581142,0.427419 Ubiquitin_H68W,Ubiquitin_68,Uba1,Ubiquitin,P0CG48,0.427419,NO,68,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-1.869,-3.325,1.456,4.81902,0.194,E,B,0.72,-1.02,21.325,21.325,65.11,HBH,-1.583,0.205827,0.000925438,0.427419 Ubiquitin_I44D,Ubiquitin_44,Uba1,Ubiquitin,P0CG48,0.427419,NO,44,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.566,-3.792,2.226,4.71256,,E,B,0.27,-1.17,5.26,,39.71,HHH,-1.38567,0.205827,0.000613305,0.427419 Ubiquitin_I61D,Ubiquitin_61,Uba1,Ubiquitin,P0CG48,0.427419,NO,61,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.514,-3.921,2.407,5.19922,0.038,,B,1,-0.76,1.953,,24.53,PHP,-1.70833,0.205827,0.000738268,0.427419 Ubiquitin_L67S,Ubiquitin_67,Uba1,Ubiquitin,P0CG48,0.427419,NO,67,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.435,-2.817,1.382,4.92156,,E,B,1.19,-1.02,6.371,6.371,30.8,PHB,-1.628,0.205827,0.000482727,0.427419 Ubiquitin_Q2G,Ubiquitin_2,Uba1,Ubiquitin,P0CG48,0.427419,NO,2,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-1.7,-3.522,1.822,4.89203,0.475,E,B,,0.1,,,,OPH,-1.551,0.205827,0.00085006,0.427419 Ubiquitin_Q40P,Ubiquitin_40,Uba1,Ubiquitin,P0CG48,0.427419,NO,40,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-1.752,-2.898,1.146,4.7807,0.387,G,A,,0.03,,,,APP,-1.62433,0.205827,0.000619089,0.427419 beta-lactamase_2500_I93Y,beta-lactamase_2500_93,TEM-1,beta-lactamase_2500,P62593,0.427523,NO,93,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.401,-4.112,2.711,,0.128,E,B,0.48,0.44,19.374,19.374,67.83,BHB,-1.873,0.361275,0.00527066,0.427523 kka2_1:1_L47V,kka2_1:1_47,Kka2,kka2_1:1,P00552,0.427609,NO,47,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.265,-2.308,1.043,,0.139,E,B,0.55,-0.86,14.593,14.593,63.26,HHH,-1.77933,0.520039,0.00509386,0.427609 beta-lactamase_39_A185P,beta-lactamase_39_185,TEM-1,beta-lactamase_39,P62593,0.42761,NO,185,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.406,-2.861,1.455,,,H,A,0.46,-1.02,2.68,,65.03,HHP,-1.84033,0.0495842,0.00467449,0.42761 beta-lactamase_625_D212F,beta-lactamase_625_212,TEM-1,beta-lactamase_625,P62593,0.427639,NO,212,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.624,-4.334,2.71,,0.037,,b,0.75,-0.58,1.516,,74.48,HAB,-1.77667,0.213352,0.00644302,0.427639 beta-lactamase_156_P65R,beta-lactamase_156_65,TEM-1,beta-lactamase_156,P62593,0.427659,NO,65,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.894,-3.951,3.057,,0.098,E,B,0.52,-0.62,0.623,,40.56,HOH,-1.03233,0.111618,0.00152776,0.427659 kka2_1:2_I207F,kka2_1:2_207,Kka2,kka2_1:2,P00552,0.427663,NO,207,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.175,-3.792,2.617,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.295029,0.00611824,0.427663 beta-lactamase_0_T139W,beta-lactamase_0_139,TEM-1,beta-lactamase_0,P62593,0.427693,NO,139,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.901,-5.432,3.531,,0.216,H,A,0.22,0.39,0.421,,77.62,PPH,-2.04667,0.0500837,0.00441837,0.427693 beta-lactamase_39_W227Q,beta-lactamase_39_227,TEM-1,beta-lactamase_39,P62593,0.427771,NO,227,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-0.982,-4.194,3.212,,0.272,,B,0.47,-0.29,1.37,,74.48,OHH,-1.595,0.0495842,0.00226019,0.427771 kka2_1:2_G210M,kka2_1:2_210,Kka2,kka2_1:2,P00552,0.42787,NO,210,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.095,-4.836,3.741,,0.103,T,A,0.29,-0.62,0.271,,50,OOB,-0.966667,0.295029,0.00598378,0.42787 kka2_1:4_G21I,kka2_1:4_21,Kka2,kka2_1:4,P00552,0.427905,NO,21,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.368,-4.201,2.833,,0.586,T,l,0.75,-0.75,3.075,,71.59,HOH,-2.10167,0.168804,0.00709648,0.427905 beta-lactamase_156_L146S,beta-lactamase_156_146,TEM-1,beta-lactamase_156,P62593,0.427942,NO,146,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.462,-2.916,1.454,,0.007,H,A,0.55,-0.56,1.578,,64.69,AHP,-1.656,0.111618,0.00474542,0.427942 beta-lactamase_L135W,beta-lactamase_135,TEM-1,beta-lactamase,P62593,0.428008,NO,135,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.002,-5.166,4.164,5.28497,0.117,H,A,1.07,-0.58,0.697,,43.71,PHH,-1.03767,0.221079,0.00244423,0.428008 kka2_1:1_G21I,kka2_1:1_21,Kka2,kka2_1:1,P00552,0.428128,NO,21,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.368,-4.201,2.833,,0.586,T,l,0.29,-0.75,10.291,10.291,71.59,HOH,-2.10167,0.520039,0.00709648,0.428128 kka2_1:1_C131Y,kka2_1:1_131,Kka2,kka2_1:1,P00552,0.428177,NO,131,C,Y,CY,Special,Hydrophobic,5.07,5.66,0.59,194,121,181,60,108.5,193.6,85.1,-0.831,-4.191,3.36,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.520039,0.00170814,0.428177 beta-lactamase_L192G,beta-lactamase_192,TEM-1,beta-lactamase,P62593,0.428191,NO,192,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.254,-3.698,2.444,5.68899,0.095,H,A,1.3,0.35,1.756,,60.14,HHP,-1.41833,0.221079,0.00558728,0.428191 kka2_1:1_M148D,kka2_1:1_148,Kka2,kka2_1:1,P00552,0.42829,NO,148,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.847,-4.109,2.262,,0.268,H,A,1.59,0.71,4.618,,64.39,BHA,-1.65467,0.520039,0.00982664,0.42829 beta-lactamase_2500_E62W,beta-lactamase_2500_62,TEM-1,beta-lactamase_2500,P62593,0.428377,NO,62,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.193,-5.409,4.216,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.361275,0.00264802,0.428377 kka2_1:1_Q61W,kka2_1:1_61,Kka2,kka2_1:1,P00552,0.428466,NO,61,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.982,-5.59,2.608,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.520039,0.00612092,0.428466 kka2_1:1_A119Y,kka2_1:1_119,Kka2,kka2_1:1,P00552,0.428469,NO,119,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.073,-4.266,3.193,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.520039,0.00441074,0.428469 Pab1_N127S,Pab1_127,Pab1,Pab1,P04147,0.428557,NO,127,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-1.079,-2.753,1.674,,0.138,E,B,1.05,-0.51,,,,OPH,-1.13633,0.175299,0.000805159,0.428557 beta-lactamase_156_D177S,beta-lactamase_156_177,TEM-1,beta-lactamase_156,P62593,0.428594,NO,177,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.967,-3.186,2.219,,0.006,T,L,0.75,-1.02,2.072,,64.69,BAP,-0.873667,0.111618,0.000864022,0.428594 kka2_1:8_I221T,kka2_1:8_221,Kka2,kka2_1:8,P00552,0.428604,NO,221,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.739,-3.548,1.809,,,H,A,1.52,-1.15,1.599,,71.59,AHH,-1.08367,0.100394,0.00945908,0.428604 kka2_1:8_I221T,kka2_1:8_221,Kka2,kka2_1:8,P00552,0.428604,NO,221,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.739,-3.548,1.809,,,H,A,1.52,-1.15,1.599,,71.59,AHH,-1.08367,0.100394,0.00945908,0.428604 beta-lactamase_S233C,beta-lactamase_233,TEM-1,beta-lactamase,P62593,0.428628,NO,233,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.886,-4.789,2.903,4.98121,0.016,E,B,0.48,-1.01,5.361,,77.62,BPO,-1.17267,0.221079,0.00311415,0.428628 kka2_1:2_L232V,kka2_1:2_232,Kka2,kka2_1:2,P00552,0.428665,NO,232,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.514,-2.443,0.929,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.295029,0.00800103,0.428665 kka2_1:4_D90P,kka2_1:4_90,Kka2,kka2_1:4,P00552,0.428771,NO,90,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.459,-4.102,1.643,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.168804,0.00583842,0.428771 kka2_1:4_G245K,kka2_1:4_245,Kka2,kka2_1:4,P00552,0.428864,NO,245,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.812,-3.635,2.823,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.168804,0.00683899,0.428864 kka2_1:1_V97M,kka2_1:1_97,Kka2,kka2_1:1,P00552,0.428926,NO,97,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.453,-2.867,1.414,,0.083,,B,1.48,-0.83,13.576,13.576,53.03,AHO,-1.85067,0.520039,0.00737869,0.428926 beta-lactamase_625_I280C,beta-lactamase_625_280,TEM-1,beta-lactamase_625,P62593,0.428944,NO,280,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.213352,0.0530888,0.428944 beta-lactamase_2500_T116G,beta-lactamase_2500_116,TEM-1,beta-lactamase_2500,P62593,0.428961,NO,116,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.28,-3.287,2.007,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.361275,0.00336175,0.428961 beta-lactamase_625_S104I,beta-lactamase_625_104,TEM-1,beta-lactamase_625,P62593,0.42899,NO,104,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.015,-3.786,2.771,,0.04,,b,0.27,0.57,1.76,,63.29,HPO,-1.05267,0.213352,0.00218083,0.42899 kka2_1:2_E182F,kka2_1:2_182,Kka2,kka2_1:2,P00552,0.429011,NO,182,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.516,-4.259,2.743,,0.326,,B,1.52,0.75,14.547,14.547,65.53,OAA,-1.806,0.295029,0.00641548,0.429011 kka2_1:1_D227G,kka2_1:1_227,Kka2,kka2_1:1,P00552,0.429015,NO,227,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.758,-3.04,1.282,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.520039,0.00745029,0.429015 kka2_1:2_F171C,kka2_1:2_171,Kka2,kka2_1:2,P00552,0.429036,NO,171,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.326,-4.966,3.64,,0.154,H,A,0.58,-0.1,2.645,,63.64,HHH,-1.45433,0.295029,0.00821426,0.429036 kka2_1:2_E96L,kka2_1:2_96,Kka2,kka2_1:2,P00552,0.429081,NO,96,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.573,-3.338,0.765,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.295029,0.00369441,0.429081 beta-lactamase_39_V31K,beta-lactamase_39_31,TEM-1,beta-lactamase_39,P62593,0.429087,NO,31,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.822,-3.873,2.051,,,H,A,0.44,-0.46,2.885,,73.78,BHB,-2.03767,0.0495842,0.00478065,0.429087 kka2_1:4_L174S,kka2_1:4_174,Kka2,kka2_1:4,P00552,0.429205,NO,174,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.952,-3.62,2.668,,,H,A,0.55,-0.31,1.339,,51.89,BHB,-2.08533,0.168804,0.00438501,0.429205 beta-lactamase_2500_L49N,beta-lactamase_2500_49,TEM-1,beta-lactamase_2500,P62593,0.429311,NO,49,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.897,-3.842,1.945,,0.131,T,A,0.55,0.04,6.681,,64.69,AHP,-1.99233,0.361275,0.00401477,0.429311 beta-lactamase_2500_D161H,beta-lactamase_2500_161,TEM-1,beta-lactamase_2500,P62593,0.429333,NO,161,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.891,-4.479,3.588,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.361275,0.000897697,0.429333 kka2_1:8_V186R,kka2_1:8_186,Kka2,kka2_1:8,P00552,0.429353,NO,186,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.011,-4.25,3.239,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.100394,0.00409703,0.429353 kka2_1:8_V186R,kka2_1:8_186,Kka2,kka2_1:8,P00552,0.429353,NO,186,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.011,-4.25,3.239,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.100394,0.00409703,0.429353 beta-lactamase_D83Y,beta-lactamase_83,TEM-1,beta-lactamase,P62593,0.429386,NO,83,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.066,-4.396,3.33,5.40616,0.354,H,A,1.33,0.22,0.861,,48.95,HAH,-1.34733,0.221079,0.00205968,0.429386 kka2_1:1_R202M,kka2_1:1_202,Kka2,kka2_1:1,P00552,0.429399,NO,202,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.761,-4.784,3.023,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.520039,0.00696498,0.429399 kka2_1:4_H188S,kka2_1:4_188,Kka2,kka2_1:4,P00552,0.429421,NO,188,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-0.913,-3.412,2.499,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.168804,0.00273139,0.429421 kka2_1:4_I221T,kka2_1:4_221,Kka2,kka2_1:4,P00552,0.42943,NO,221,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.739,-3.548,1.809,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.168804,0.00945908,0.42943 kka2_1:8_K112Y,kka2_1:8_112,Kka2,kka2_1:8,P00552,0.429446,NO,112,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-2.491,-4.32,1.829,,0.076,H,A,1.3,-1.37,10.58,10.58,56.06,ABH,-2.00133,0.100394,0.00645389,0.429446 kka2_1:8_K112Y,kka2_1:8_112,Kka2,kka2_1:8,P00552,0.429446,NO,112,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-2.491,-4.32,1.829,,0.076,H,A,1.3,-1.37,10.58,10.58,56.06,ABH,-2.00133,0.100394,0.00645389,0.429446 kka2_1:1_E231Q,kka2_1:1_231,Kka2,kka2_1:1,P00552,0.429449,NO,231,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.002,-3.771,1.769,,0.503,H,A,1.04,-0.23,25.629,25.629,63.26,AAH,-2.06267,0.520039,0.00732383,0.429449 kka2_1:1_T146C,kka2_1:1_146,Kka2,kka2_1:1,P00552,0.429456,NO,146,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.978,-5.009,2.031,,0.281,H,A,0.82,0.78,2.105,,92.05,BPB,-1.96833,0.520039,0.00606474,0.429456 beta-lactamase_2500_R220G,beta-lactamase_2500_220,TEM-1,beta-lactamase_2500,P62593,0.429538,NO,220,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-0.942,-3.321,2.379,,0.295,I,A,1.2,-0.76,2.175,,74.48,HBP,-1.33633,0.361275,0.00232421,0.429538 kka2_1:1_A150H,kka2_1:1_150,Kka2,kka2_1:1,P00552,0.429574,NO,150,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.949,-4.695,3.746,,0.544,T,A,0.46,1.34,2.333,,63.26,AHO,-1.272,0.520039,0.0045009,0.429574 kka2_1:1_D216K,kka2_1:1_216,Kka2,kka2_1:1,P00552,0.42962,NO,216,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.785,-3.508,2.723,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.520039,0.00229969,0.42962 beta-lactamase_625_N274I,beta-lactamase_625_274,TEM-1,beta-lactamase_625,P62593,0.429623,NO,274,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.213352,0.0110418,0.429623 kka2_1:2_G189S,kka2_1:2_189,Kka2,kka2_1:2,P00552,0.429627,NO,189,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.596,-3.189,2.593,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.295029,0.00253688,0.429627 kka2_1:2_H135Q,kka2_1:2_135,Kka2,kka2_1:2,P00552,0.429672,NO,135,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-1.331,-2.136,0.805,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.295029,0.00532566,0.429672 kka2_1:8_A144F,kka2_1:8_144,Kka2,kka2_1:8,P00552,0.429682,NO,144,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.859,-4.095,3.236,,,H,A,1.04,0.21,1.118,,52.65,BHB,-1.72933,0.100394,0.00231095,0.429682 kka2_1:8_A144F,kka2_1:8_144,Kka2,kka2_1:8,P00552,0.429682,NO,144,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.859,-4.095,3.236,,,H,A,1.04,0.21,1.118,,52.65,BHB,-1.72933,0.100394,0.00231095,0.429682 kka2_1:8_A144H,kka2_1:8_144,Kka2,kka2_1:8,P00552,0.429682,NO,144,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.859,-4.791,3.932,,,H,A,1.04,0.21,1.118,,52.65,BHB,-1.72933,0.100394,0.00231095,0.429682 kka2_1:8_A144H,kka2_1:8_144,Kka2,kka2_1:8,P00552,0.429682,NO,144,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.859,-4.791,3.932,,,H,A,1.04,0.21,1.118,,52.65,BHB,-1.72933,0.100394,0.00231095,0.429682 beta-lactamase_2500_Q88P,beta-lactamase_2500_88,TEM-1,beta-lactamase_2500,P62593,0.429736,NO,88,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.086,-3.948,1.862,,0.807,,B,0.64,2.03,1.84,,77.62,APH,-1.53433,0.361275,0.00504167,0.429736 kka2_1:4_C209I,kka2_1:4_209,Kka2,kka2_1:4,P00552,0.429745,NO,209,C,I,CI,Special,Hydrophobic,5.07,6.02,0.95,198,121,131,10,108.5,166.7,58.2,-0.906,-3.519,2.613,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.168804,0.00260862,0.429745 beta-lactamase_625_I229Y,beta-lactamase_625_229,TEM-1,beta-lactamase_625,P62593,0.429754,NO,229,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.267,-4.04,2.773,,0.083,E,B,0.48,-0.76,1.69,,50,HHH,-1.58767,0.213352,0.00477249,0.429754 kka2_1:1_R253G,kka2_1:1_253,Kka2,kka2_1:1,P00552,0.429765,NO,253,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.356,-3.453,2.097,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.520039,0.0144195,0.429765 kka2_1:1_P76G,kka2_1:1_76,Kka2,kka2_1:1,P00552,0.429767,NO,76,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.449,-3.458,2.009,,0.331,.,B,0.52,-0.41,0.345,,63.64,HOO,-1.662,0.520039,0.00625685,0.429767 kka2_1:8_N195C,kka2_1:8_195,Kka2,kka2_1:8,P00552,0.429819,NO,195,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-0.836,-5.139,4.303,,0.037,G,A,0.43,-1.36,1.108,,48.11,OPH,-1.26567,0.100394,0.00276134,0.429819 kka2_1:8_N195C,kka2_1:8_195,Kka2,kka2_1:8,P00552,0.429819,NO,195,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-0.836,-5.139,4.303,,0.037,G,A,0.43,-1.36,1.108,,48.11,OPH,-1.26567,0.100394,0.00276134,0.429819 beta-lactamase_L223P,beta-lactamase_223,TEM-1,beta-lactamase,P62593,0.429848,NO,223,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.055,-4.101,3.046,5.42318,0.27,,B,1.3,0.09,1.511,,74.48,HHO,-1.35033,0.221079,0.00372793,0.429848 kka2_1:1_L184C,kka2_1:1_184,Kka2,kka2_1:1,P00552,0.429907,NO,184,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.496,-5.02,3.524,,0.489,E,B,0.55,-0.06,19.127,19.127,63.26,AHH,-1.24833,0.520039,0.00518742,0.429907 kka2_1:4_I115N,kka2_1:4_115,Kka2,kka2_1:4,P00552,0.429948,NO,115,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.606,-4.227,2.621,,0.105,H,A,1.52,-1.18,9.996,9.996,65.53,PHH,-2.205,0.168804,0.00836567,0.429948 beta-lactamase_2500_D161M,beta-lactamase_2500_161,TEM-1,beta-lactamase_2500,P62593,0.429957,NO,161,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.891,-4.899,4.008,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.361275,0.000897697,0.429957 kka2_1:8_D220V,kka2_1:8_220,Kka2,kka2_1:8,P00552,0.430006,NO,220,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.787,-2.698,1.911,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.100394,0.00158066,0.430006 kka2_1:8_D220V,kka2_1:8_220,Kka2,kka2_1:8,P00552,0.430006,NO,220,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.787,-2.698,1.911,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.100394,0.00158066,0.430006 kka2_1:8_F48H,kka2_1:8_48,Kka2,kka2_1:8,P00552,0.430006,NO,48,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.453,-4.549,3.096,,0.296,E,B,1.62,-0.99,14.194,14.194,55.3,HHH,-1.444,0.100394,0.00475422,0.430006 kka2_1:8_F48H,kka2_1:8_48,Kka2,kka2_1:8,P00552,0.430006,NO,48,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.453,-4.549,3.096,,0.296,E,B,1.62,-0.99,14.194,14.194,55.3,HHH,-1.444,0.100394,0.00475422,0.430006 kka2_1:2_G189L,kka2_1:2_189,Kka2,kka2_1:2,P00552,0.43008,NO,189,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.596,-3.836,3.24,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.295029,0.00253688,0.43008 beta-lactamase_2500_L160Q,beta-lactamase_2500_160,TEM-1,beta-lactamase_2500,P62593,0.430098,NO,160,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.977,-4.199,3.222,,0.022,,B,0.55,-0.6,0.895,,44.41,BHA,-0.936,0.361275,0.00193775,0.430098 kka2_1:2_G205R,kka2_1:2_205,Kka2,kka2_1:2,P00552,0.430134,NO,205,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.596,-3.961,3.365,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.295029,0.00221855,0.430134 kka2_1:1_Y22M,kka2_1:1_22,Kka2,kka2_1:1,P00552,0.43015,NO,22,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-1.583,-4.724,3.141,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.520039,0.00598977,0.43015 kka2_1:4_C77W,kka2_1:4_77,Kka2,kka2_1:4,P00552,0.430183,NO,77,C,W,CW,Special,Hydrophobic,5.07,5.89,0.82,215,121,204,83,108.5,227.8,119.3,-1.477,-5.341,3.864,,0.229,B,b,0.46,-0.57,2.499,,63.26,OOH,-1.55667,0.168804,0.00441216,0.430183 kka2_1:4_T187G,kka2_1:4_187,Kka2,kka2_1:4,P00552,0.430201,NO,187,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.273,-3.394,2.121,,0.007,E,B,0.22,-0.85,2.73,,52.27,HPB,-1.06567,0.168804,0.00693073,0.430201 beta-lactamase_625_L218A,beta-lactamase_625_218,TEM-1,beta-lactamase_625,P62593,0.430203,NO,218,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.391,-3.175,1.784,,,I,b,0.55,-0.53,17.202,17.202,74.48,OHH,-1.58867,0.213352,0.00618274,0.430203 beta-lactamase_0_S128W,beta-lactamase_0_128,TEM-1,beta-lactamase_0,P62593,0.430346,NO,128,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-0.84,-5.322,4.482,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.0500837,0.00071483,0.430346 beta-lactamase_2500_P217W,beta-lactamase_2500_217,TEM-1,beta-lactamase_2500,P62593,0.430354,NO,217,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-2.062,-5.565,3.503,,0.496,I,A,0.52,-0.33,0.431,,74.48,OOH,-1.64333,0.361275,0.00463211,0.430354 kka2_1:1_A144K,kka2_1:1_144,Kka2,kka2_1:1,P00552,0.430366,NO,144,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.859,-3.568,2.709,,,H,A,0.46,0.21,0.842,,52.65,BHB,-1.72933,0.520039,0.00231095,0.430366 kka2_1:1_D159P,kka2_1:1_159,Kka2,kka2_1:1,P00552,0.430464,NO,159,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.82,-3.747,2.927,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.520039,0.0030485,0.430464 beta-lactamase_0_G76Q,beta-lactamase_0_76,TEM-1,beta-lactamase_0,P62593,0.430469,NO,76,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.189,-4.074,2.885,,,H,A,0.29,-0.67,1.188,,67.83,OOH,-1.22267,0.0500837,0.00476637,0.430469 beta-lactamase_156_I140D,beta-lactamase_156_140,TEM-1,beta-lactamase_156,P62593,0.43049,NO,140,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.733,-4.079,2.346,,0.128,H,A,0.48,0.41,1.16,,73.08,PHO,-1.48733,0.111618,0.00597777,0.43049 kka2_1:1_R38C,kka2_1:1_38,Kka2,kka2_1:1,P00552,0.430524,NO,38,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.207,-4.996,3.789,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.520039,0.00372499,0.430524 beta-lactamase_2500_G114Y,beta-lactamase_2500_114,TEM-1,beta-lactamase_2500,P62593,0.430572,NO,114,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.094,-4.391,3.297,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.361275,0.00224919,0.430572 kka2_1:2_P128F,kka2_1:2_128,Kka2,kka2_1:2,P00552,0.430584,NO,128,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.922,-4.049,2.127,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.295029,0.00774689,0.430584 kka2_1:2_L212R,kka2_1:2_212,Kka2,kka2_1:2,P00552,0.430676,NO,212,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.904,-4.001,3.097,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.295029,0.0031426,0.430676 beta-lactamase_2500_G52P,beta-lactamase_2500_52,TEM-1,beta-lactamase_2500,P62593,0.430777,NO,52,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.149,-2.849,1.7,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.361275,0.00340138,0.430777 kka2_1:2_L212H,kka2_1:2_212,Kka2,kka2_1:2,P00552,0.4308,NO,212,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.904,-4.956,4.052,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.295029,0.0031426,0.4308 kka2_1:1_D208T,kka2_1:1_208,Kka2,kka2_1:1,P00552,0.430829,NO,208,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.708,-3.45,2.742,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.520039,0.00212588,0.430829 beta-lactamase_2500_A40W,beta-lactamase_2500_40,TEM-1,beta-lactamase_2500,P62593,0.43084,NO,40,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.402,-5.298,3.896,,0.155,S,B,0.46,0.21,0.953,,73.78,OHB,-1.40267,0.361275,0.00490026,0.43084 kka2_1:2_C77L,kka2_1:2_77,Kka2,kka2_1:2,P00552,0.430846,NO,77,C,L,CL,Special,Hydrophobic,5.07,9.7088,4.6388,198,121,131,10,108.5,166.7,58.2,-1.477,-3.33,1.853,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.295029,0.00441216,0.430846 beta-lactamase_625_Y103E,beta-lactamase_625_103,TEM-1,beta-lactamase_625,P62593,0.430858,NO,103,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-1.33,-3.564,2.234,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.213352,0.00443048,0.430858 kka2_1:8_H188W,kka2_1:8_188,Kka2,kka2_1:8,P00552,0.430931,NO,188,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-0.913,-5.149,4.236,,0.006,,A,0.87,-1.02,1.241,,47.73,PBO,-0.927333,0.100394,0.00273139,0.430931 kka2_1:8_H188W,kka2_1:8_188,Kka2,kka2_1:8,P00552,0.430931,NO,188,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-0.913,-5.149,4.236,,0.006,,A,0.87,-1.02,1.241,,47.73,PBO,-0.927333,0.100394,0.00273139,0.430931 kka2_1:1_D157A,kka2_1:1_157,Kka2,kka2_1:1,P00552,0.430995,NO,157,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.993,-3.298,2.305,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.520039,0.0042313,0.430995 Pab1_H172E,Pab1_172,Pab1,Pab1,P04147,0.43105,NO,172,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-1.21,-3.032,1.822,,0.076,E,B,0.35,-0.87,,,,HBH,-1.26667,0.175299,0.000296642,0.43105 beta-lactamase_625_E35I,beta-lactamase_625_35,TEM-1,beta-lactamase_625,P62593,0.431135,NO,35,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-0.869,-4.036,3.167,,0.15,H,A,1.04,0.21,0.664,,46.85,HAA,-1.88667,0.213352,0.00174441,0.431135 kka2_1:1_D190R,kka2_1:1_190,Kka2,kka2_1:1,P00552,0.431159,NO,190,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.708,-3.961,3.253,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.520039,0.00247989,0.431159 beta-lactamase_39_L150R,beta-lactamase_39_150,TEM-1,beta-lactamase_39,P62593,0.431204,NO,150,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.326,-3.982,2.656,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.0495842,0.00463171,0.431204 kka2_1:1_K175M,kka2_1:1_175,Kka2,kka2_1:1,P00552,0.431244,NO,175,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-2.897,-3.26,0.363,,0.579,H,A,1.3,0.51,9.33,9.33,71.59,HBH,-1.82333,0.520039,0.00693093,0.431244 kka2_1:1_L57H,kka2_1:1_57,Kka2,kka2_1:1,P00552,0.431268,NO,57,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.898,-2.613,0.715,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.520039,0.00723769,0.431268 kka2_1:1_L57A,kka2_1:1_57,Kka2,kka2_1:1,P00552,0.431338,NO,57,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.898,-3.394,1.496,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.520039,0.00723769,0.431338 kka2_1:1_L57D,kka2_1:1_57,Kka2,kka2_1:1,P00552,0.431338,NO,57,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.898,-4.048,2.15,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.520039,0.00723769,0.431338 beta-lactamase_2500_V42G,beta-lactamase_2500_42,TEM-1,beta-lactamase_2500,P62593,0.431367,NO,42,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.564,-2.773,1.209,,0.017,E,B,0.44,-0.51,1.86,,63.99,BHO,-1.042,0.361275,0.00404515,0.431367 kka2_1:1_K112N,kka2_1:1_112,Kka2,kka2_1:1,P00552,0.431385,NO,112,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-2.491,-3.976,1.485,,0.076,H,A,2.34,-1.37,23.433,23.433,56.06,ABH,-2.00133,0.520039,0.00645389,0.431385 beta-lactamase_156_S241P,beta-lactamase_156_241,TEM-1,beta-lactamase_156,P62593,0.431482,NO,241,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.111618,0.00452736,0.431482 kka2_1:2_Y22E,kka2_1:2_22,Kka2,kka2_1:2,P00552,0.431509,NO,22,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-1.583,-3.743,2.16,,0.122,.,B,0.21,-0.8,1.838,,65.53,OHA,-1.80333,0.295029,0.00598977,0.431509 beta-lactamase_2500_R91V,beta-lactamase_2500_91,TEM-1,beta-lactamase_2500,P62593,0.43155,NO,91,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.392,-3.661,2.269,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.361275,0.00380226,0.43155 kka2_1:1_V214Y,kka2_1:1_214,Kka2,kka2_1:1,P00552,0.431582,NO,214,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.261,-4.127,2.866,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.520039,0.00692782,0.431582 beta-lactamase_2500_M66H,beta-lactamase_2500_66,TEM-1,beta-lactamase_2500,P62593,0.431603,NO,66,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.362,-4.866,3.504,,0.013,,A,0.55,-0.7,0.502,,73.08,OHH,-1.49567,0.361275,0.00412876,0.431603 kka2_1:8_F203D,kka2_1:8_203,Kka2,kka2_1:8,P00552,0.43168,NO,203,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-0.911,-4.011,3.1,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.100394,0.00318738,0.43168 kka2_1:8_F203D,kka2_1:8_203,Kka2,kka2_1:8,P00552,0.43168,NO,203,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-0.911,-4.011,3.1,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.100394,0.00318738,0.43168 kka2_1:8_A191R,kka2_1:8_191,Kka2,kka2_1:8,P00552,0.431727,NO,191,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.831,-3.8,2.969,,,,b,1.04,-0.94,1.306,,50,AHO,-0.868667,0.100394,0.00338807,0.431727 kka2_1:8_A191R,kka2_1:8_191,Kka2,kka2_1:8,P00552,0.431727,NO,191,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.831,-3.8,2.969,,,,b,1.04,-0.94,1.306,,50,AHO,-0.868667,0.100394,0.00338807,0.431727 kka2_1:8_C209K,kka2_1:8_209,Kka2,kka2_1:8,P00552,0.431727,NO,209,C,K,CK,Special,PositiveCharge,5.07,9.74,4.67,202,121,146,25,108.5,168.6,60.1,-0.906,-3.933,3.027,,,,a,1.5,-0.89,0.391,,19.32,AOO,-0.903,0.100394,0.00260862,0.431727 kka2_1:8_C209K,kka2_1:8_209,Kka2,kka2_1:8,P00552,0.431727,NO,209,C,K,CK,Special,PositiveCharge,5.07,9.74,4.67,202,121,146,25,108.5,168.6,60.1,-0.906,-3.933,3.027,,,,a,1.5,-0.89,0.391,,19.32,AOO,-0.903,0.100394,0.00260862,0.431727 beta-lactamase_G279Q,beta-lactamase_279,TEM-1,beta-lactamase,P62593,0.431766,NO,279,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.038,-4.047,3.009,4.53882,,H,A,0.46,-0.97,3.066,,62.59,HOH,-1.36467,0.221079,0.0192826,0.431766 beta-lactamase_L49D,beta-lactamase_49,TEM-1,beta-lactamase,P62593,0.431766,NO,49,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.897,-3.778,1.881,5.86005,0.131,T,A,1.3,0.04,3.112,,64.69,AHP,-1.99233,0.221079,0.00401477,0.431766 kka2_1:2_I115E,kka2_1:2_115,Kka2,kka2_1:2,P00552,0.43178,NO,115,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.606,-3.967,2.361,,0.105,H,A,0.48,-1.18,0.878,,65.53,PHH,-2.205,0.295029,0.00836567,0.43178 Pab1_V198R,Pab1_198,Pab1,Pab1,P04147,0.43184,NO,198,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.113,-3.975,2.862,,0.008,E,B,0.61,0.91,,,,HHH,-1.32933,0.175299,0.000268557,0.43184 beta-lactamase_625_Y95S,beta-lactamase_625_95,TEM-1,beta-lactamase_625,P62593,0.431841,NO,95,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-1.715,-3.776,2.061,,0.122,,b,0.21,-0.37,3.355,,77.62,BHP,-2.16167,0.213352,0.00479449,0.431841 kka2_1:1_T28Y,kka2_1:1_28,Kka2,kka2_1:1,P00552,0.431938,NO,28,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.883,-4.4,2.517,,0.353,S,B,0.22,2.02,1.12,,63.64,PPH,-1.74467,0.520039,0.00743084,0.431938 beta-lactamase_625_V117S,beta-lactamase_625_117,TEM-1,beta-lactamase_625,P62593,0.431966,NO,117,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.53,-3.729,2.199,,,H,A,0.44,-0.34,1.23,,65.03,PHB,-1.741,0.213352,0.00467906,0.431966 kka2_1:1_R140A,kka2_1:1_140,Kka2,kka2_1:1,P00552,0.431972,NO,140,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.351,-2.609,1.258,,0.12,H,A,1.2,0.2,11.345,11.345,53.03,BBH,-1.885,0.520039,0.00430167,0.431972 beta-lactamase_2500_V42A,beta-lactamase_2500_42,TEM-1,beta-lactamase_2500,P62593,0.432035,NO,42,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.564,-2.554,0.99,,0.017,E,B,0.44,-0.51,1.86,,63.99,BHO,-1.042,0.361275,0.00404515,0.432035 kka2_1:2_D261S,kka2_1:2_261,Kka2,kka2_1:2,P00552,0.432066,NO,261,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.708,-3.189,2.481,,0.146,G,A,0.75,-0.33,,,,HAA,-0.759333,0.295029,0.0224846,0.432066 kka2_1:1_P132R,kka2_1:1_132,Kka2,kka2_1:1,P00552,0.432177,NO,132,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.775,-3.959,3.184,,0.692,.,A,0.52,0.56,0.224,,44.7,OOH,-0.825667,0.520039,0.0018489,0.432177 kka2_1:8_C192P,kka2_1:8_192,Kka2,kka2_1:8,P00552,0.43218,NO,192,C,P,CP,Special,Special,5.07,6.3,1.23,169,121,115,-6,108.5,112.7,4.2,-1.067,-4.099,3.032,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.100394,0.00485428,0.43218 kka2_1:8_C192P,kka2_1:8_192,Kka2,kka2_1:8,P00552,0.43218,NO,192,C,P,CP,Special,Special,5.07,6.3,1.23,169,121,115,-6,108.5,112.7,4.2,-1.067,-4.099,3.032,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.100394,0.00485428,0.43218 kka2_1:4_R38S,kka2_1:4_38,Kka2,kka2_1:4,P00552,0.432221,NO,38,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.207,-3.563,2.356,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.168804,0.00372499,0.432221 kka2_1:1_P98A,kka2_1:1_98,Kka2,kka2_1:1,P00552,0.43237,NO,98,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.526,-2.324,0.798,,0.391,S,B,0.52,-0.65,1.521,,63.26,HOO,-1.19167,0.520039,0.00622754,0.43237 kka2_1:1_A9I,kka2_1:1_9,Kka2,kka2_1:1,P00552,0.432413,NO,9,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.079,-2.507,0.428,,,,,,,0.383,,71.59,BHO,-2.253,0.520039,0.00273264,0.432413 kka2_1:1_P109A,kka2_1:1_109,Kka2,kka2_1:1,P00552,0.432446,NO,109,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.412,-1.957,0.545,,0.376,H,A,0.52,-1.25,18.506,18.506,65.53,HOH,-1.84567,0.520039,0.0070929,0.432446 beta-lactamase_2500_R220S,beta-lactamase_2500_220,TEM-1,beta-lactamase_2500,P62593,0.432493,NO,220,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-0.942,-3.349,2.407,,0.295,I,A,1.2,-0.76,2.175,,74.48,HBP,-1.33633,0.361275,0.00232421,0.432493 beta-lactamase_39_G76D,beta-lactamase_39_76,TEM-1,beta-lactamase_39,P62593,0.432529,NO,76,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.189,-3.614,2.425,,,H,A,0.29,-0.67,2.145,,67.83,OOH,-1.22267,0.0495842,0.00476637,0.432529 kka2_1:4_I141N,kka2_1:4_141,Kka2,kka2_1:4,P00552,0.432543,NO,141,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.495,-4.275,2.78,,0.068,H,A,0.48,-0.01,2.144,,92.05,BHA,-1.689,0.168804,0.00744745,0.432543 kka2_1:1_A172G,kka2_1:1_172,Kka2,kka2_1:1,P00552,0.432587,NO,172,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.757,-2.418,0.661,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.520039,0.0079265,0.432587 Pab1_A182P,Pab1_182,Pab1,Pab1,P04147,0.43263,NO,182,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.013,-3.472,2.459,,,H,A,0.17,0.79,,,,AHH,-1.36067,0.175299,0.000289034,0.43263 kka2_1:4_D190C,kka2_1:4_190,Kka2,kka2_1:4,P00552,0.432716,NO,190,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.708,-5.115,4.407,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.168804,0.00247989,0.432716 beta-lactamase_2500_W208A,beta-lactamase_2500_208,TEM-1,beta-lactamase_2500,P62593,0.432815,NO,208,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-0.818,-3.528,2.71,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.361275,0.00126609,0.432815 kka2_1:1_T28R,kka2_1:1_28,Kka2,kka2_1:1,P00552,0.432822,NO,28,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.883,-3.259,1.376,,0.353,S,B,0.22,2.02,1.12,,63.64,PPH,-1.74467,0.520039,0.00743084,0.432822 kka2_1:1_G164W,kka2_1:1_164,Kka2,kka2_1:1,P00552,0.432894,NO,164,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.869,-5.307,4.438,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.520039,0.00442091,0.432894 kka2_1:1_I196W,kka2_1:1_196,Kka2,kka2_1:1,P00552,0.432956,NO,196,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-2.115,-4.933,2.818,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.520039,0.0107273,0.432956 kka2_1:1_D62N,kka2_1:1_62,Kka2,kka2_1:1,P00552,0.433043,NO,62,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.591,-2.947,1.356,,0.262,H,A,0.75,0.08,10.048,10.048,64.39,PAA,-1.77833,0.520039,0.00744243,0.433043 kka2_1:1_R66V,kka2_1:1_66,Kka2,kka2_1:1,P00552,0.433044,NO,66,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-0.922,-3.78,2.858,,0.103,H,A,1.2,-0.2,2.659,,46.21,HBH,-1.13567,0.520039,0.00161025,0.433044 beta-lactamase_2500_G281V,beta-lactamase_2500_281,TEM-1,beta-lactamase_2500,P62593,0.433098,NO,281,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.361275,0.0406482,0.433098 beta-lactamase_625_M115N,beta-lactamase_625_115,TEM-1,beta-lactamase_625,P62593,0.433127,NO,115,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.389,-4.013,2.624,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.213352,0.0034337,0.433127 beta-lactamase_156_T69N,beta-lactamase_156_69,TEM-1,beta-lactamase_156,P62593,0.433175,NO,69,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-0.973,-3.537,2.564,,,G,A,0.22,-1.24,4.194,,93.01,PPH,-1.01833,0.111618,0.00127498,0.433175 beta-lactamase_625_R220T,beta-lactamase_625_220,TEM-1,beta-lactamase_625,P62593,0.433202,NO,220,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-0.942,-3.419,2.477,,0.295,I,A,1.2,-0.76,5.086,,74.48,HBP,-1.33633,0.213352,0.00232421,0.433202 kka2_1:8_S204D,kka2_1:8_204,Kka2,kka2_1:8,P00552,0.433241,NO,204,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.353,-3.549,2.196,,0.144,E,A,0.27,-1.2,0.368,,65.53,HPO,-0.953333,0.100394,0.00881794,0.433241 kka2_1:8_S204D,kka2_1:8_204,Kka2,kka2_1:8,P00552,0.433241,NO,204,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.353,-3.549,2.196,,0.144,E,A,0.27,-1.2,0.368,,65.53,HPO,-0.953333,0.100394,0.00881794,0.433241 kka2_1:8_I221D,kka2_1:8_221,Kka2,kka2_1:8,P00552,0.433253,NO,221,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.739,-4.188,2.449,,,H,A,1.52,-1.15,1.599,,71.59,AHH,-1.08367,0.100394,0.00945908,0.433253 kka2_1:8_I221D,kka2_1:8_221,Kka2,kka2_1:8,P00552,0.433253,NO,221,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.739,-4.188,2.449,,,H,A,1.52,-1.15,1.599,,71.59,AHH,-1.08367,0.100394,0.00945908,0.433253 beta-lactamase_625_L218P,beta-lactamase_625_218,TEM-1,beta-lactamase_625,P62593,0.433256,NO,218,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.391,-4.052,2.661,,,I,b,0.55,-0.53,17.202,17.202,74.48,OHH,-1.58867,0.213352,0.00618274,0.433256 beta-lactamase_2500_P224E,beta-lactamase_2500_224,TEM-1,beta-lactamase_2500,P62593,0.43327,NO,224,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.893,-3.439,2.546,,0.383,,B,0.52,-0.3,2.666,,74.48,HOH,-1.26433,0.361275,0.00189564,0.43327 beta-lactamase_D212I,beta-lactamase_212,TEM-1,beta-lactamase,P62593,0.433343,NO,212,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.624,-3.045,1.421,4.9705,0.037,,b,1.3,-0.58,12.482,,74.48,HAB,-1.77667,0.221079,0.00644302,0.433343 beta-lactamase_2500_P224M,beta-lactamase_2500_224,TEM-1,beta-lactamase_2500,P62593,0.433377,NO,224,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.893,-4.704,3.811,,0.383,,B,0.52,-0.3,2.666,,74.48,HOH,-1.26433,0.361275,0.00189564,0.433377 beta-lactamase_W286P,beta-lactamase_286,TEM-1,beta-lactamase,P62593,0.433378,NO,286,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-1.111,-4.147,3.036,6.64456,0.492,,?,0.01,0.6,,,,BHX,-1.478,0.221079,,0.433378 beta-lactamase_2500_P65S,beta-lactamase_2500_65,TEM-1,beta-lactamase_2500,P62593,0.433412,NO,65,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.894,-3.44,2.546,,0.098,E,B,0.52,-0.62,0.3,,40.56,HOH,-1.03233,0.361275,0.00152776,0.433412 beta-lactamase_156_R257Y,beta-lactamase_156_257,TEM-1,beta-lactamase_156,P62593,0.433548,NO,257,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.111618,0.00756629,0.433548 kka2_1:8_V113H,kka2_1:8_113,Kka2,kka2_1:8,P00552,0.433555,NO,113,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.233,-5.033,3.8,,0.008,H,A,1.48,-1.17,1.254,,52.27,BHP,-2.08367,0.100394,0.00650191,0.433555 kka2_1:8_V113H,kka2_1:8_113,Kka2,kka2_1:8,P00552,0.433555,NO,113,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.233,-5.033,3.8,,0.008,H,A,1.48,-1.17,1.254,,52.27,BHP,-2.08367,0.100394,0.00650191,0.433555 kka2_1:8_V113Y,kka2_1:8_113,Kka2,kka2_1:8,P00552,0.433555,NO,113,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.233,-4.11,2.877,,0.008,H,A,1.48,-1.17,1.254,,52.27,BHP,-2.08367,0.100394,0.00650191,0.433555 kka2_1:8_V113Y,kka2_1:8_113,Kka2,kka2_1:8,P00552,0.433555,NO,113,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.233,-4.11,2.877,,0.008,H,A,1.48,-1.17,1.254,,52.27,BHP,-2.08367,0.100394,0.00650191,0.433555 beta-lactamase_625_P65T,beta-lactamase_625_65,TEM-1,beta-lactamase_625,P62593,0.433565,NO,65,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.894,-3.44,2.546,,0.098,E,B,0.52,-0.62,0.3,,40.56,HOH,-1.03233,0.213352,0.00152776,0.433565 kka2_1:1_T28F,kka2_1:1_28,Kka2,kka2_1:1,P00552,0.433697,NO,28,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.883,-4.355,2.472,,0.353,S,B,0.22,2.02,1.12,,63.64,PPH,-1.74467,0.520039,0.00743084,0.433697 kka2_1:1_G210R,kka2_1:1_210,Kka2,kka2_1:1,P00552,0.433771,NO,210,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.095,-4.007,2.912,,0.103,T,A,0.29,-0.62,14.483,14.483,50,OOB,-0.966667,0.520039,0.00598378,0.433771 kka2_1:2_C131V,kka2_1:2_131,Kka2,kka2_1:2,P00552,0.433802,NO,131,C,V,CV,Special,Hydrophobic,5.07,5.60847,0.538465,192,121,117,-4,108.5,140,31.5,-0.831,-3.332,2.501,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.295029,0.00170814,0.433802 kka2_1:4_M148F,kka2_1:4_148,Kka2,kka2_1:4,P00552,0.433818,NO,148,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.847,-4.011,2.164,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.168804,0.00982664,0.433818 beta-lactamase_156_F64C,beta-lactamase_156_64,TEM-1,beta-lactamase_156,P62593,0.433836,NO,64,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-0.841,-4.862,4.021,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.111618,0.000947691,0.433836 kka2_1:1_E182V,kka2_1:1_182,Kka2,kka2_1:1,P00552,0.433841,NO,182,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.516,-3.667,2.151,,0.326,,B,1.52,0.75,14.547,14.547,65.53,OAA,-1.806,0.520039,0.00641548,0.433841 beta-lactamase_2500_L188W,beta-lactamase_2500_188,TEM-1,beta-lactamase_2500,P62593,0.433853,NO,188,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.166,-3.108,1.942,,,H,A,0.55,-0.3,17.865,17.865,60.14,PHB,-1.47033,0.361275,0.00295687,0.433853 kka2_1:1_Q26W,kka2_1:1_26,Kka2,kka2_1:1,P00552,0.433874,NO,26,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.18,-5.501,3.321,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.520039,0.00708962,0.433874 beta-lactamase_625_I93N,beta-lactamase_625_93,TEM-1,beta-lactamase_625,P62593,0.433875,NO,93,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.401,-4.175,2.774,,0.128,E,B,0.48,0.44,1.524,,67.83,BHB,-1.873,0.213352,0.00527066,0.433875 kka2_1:4_A65P,kka2_1:4_65,Kka2,kka2_1:4,P00552,0.433895,NO,65,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.744,-4.019,2.275,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.168804,0.00709258,0.433895 beta-lactamase_625_A84P,beta-lactamase_625_84,TEM-1,beta-lactamase_625,P62593,0.433965,NO,84,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.651,-3.933,2.282,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.213352,0.00503822,0.433965 kka2_1:1_E262D,kka2_1:1_262,Kka2,kka2_1:1,P00552,0.43399,NO,262,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-0.829,-2.883,2.054,,0.059,G,A,1.04,-0.18,0.837,,42.42,AAH,-0.816,0.520039,0.0191586,0.43399 kka2_1:1_H135I,kka2_1:1_135,Kka2,kka2_1:1,P00552,0.434017,NO,135,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-1.331,-3.976,2.645,,0.071,.,a,0.17,0.65,3.574,,53.03,ABP,-1.77367,0.520039,0.00532566,0.434017 kka2_1:1_T51F,kka2_1:1_51,Kka2,kka2_1:1,P00552,0.434056,NO,51,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.199,-4.265,2.066,,0.05,E,B,0.22,-0.05,3.056,,63.64,BPA,-1.76767,0.520039,0.00628861,0.434056 kka2_1:1_A25G,kka2_1:1_25,Kka2,kka2_1:1,P00552,0.434129,NO,25,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.496,-3.533,1.037,,0.427,E,B,0.46,-0.47,6.872,6.872,65.53,HHP,-2.15167,0.520039,0.00595636,0.434129 beta-lactamase_39_W208P,beta-lactamase_39_208,TEM-1,beta-lactamase_39,P62593,0.43414,NO,208,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-0.818,-4.33,3.512,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.0495842,0.00126609,0.43414 beta-lactamase_625_E87P,beta-lactamase_625_87,TEM-1,beta-lactamase_625,P62593,0.434141,NO,87,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.421,-3.872,2.451,,0.048,,B,1.04,0.92,17.923,17.923,64.69,PAP,-1.969,0.213352,0.00337888,0.434141 beta-lactamase_156_T158H,beta-lactamase_156_158,TEM-1,beta-lactamase_156,P62593,0.434145,NO,158,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.116,-4.689,3.573,,0.036,,B,0.22,-0.85,3.771,,69.58,HPB,-1.269,0.111618,0.00341825,0.434145 kka2_1:1_P132G,kka2_1:1_132,Kka2,kka2_1:1,P00552,0.434164,NO,132,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.775,-3.354,2.579,,0.692,.,A,0.52,0.56,0.224,,44.7,OOH,-0.825667,0.520039,0.0018489,0.434164 beta-lactamase_L79T,beta-lactamase_79,TEM-1,beta-lactamase,P62593,0.434316,NO,79,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.842,-3.447,2.605,4.98681,0.007,H,A,1.07,-0.16,0.823,,50.35,HHP,-1.44333,0.221079,0.000947397,0.434316 kka2_1:4_H124K,kka2_1:4_124,Kka2,kka2_1:4,P00552,0.434358,NO,124,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-0.84,-3.485,2.645,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.168804,0.00211296,0.434358 kka2_1:4_W24P,kka2_1:4_24,Kka2,kka2_1:4,P00552,0.434389,NO,24,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-1.779,-4.359,2.58,,0.477,E,B,1.51,-0.21,2.666,,56.06,AHH,-2.24467,0.168804,0.00631564,0.434389 kka2_1:1_G205Q,kka2_1:1_205,Kka2,kka2_1:1,P00552,0.434448,NO,205,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.596,-4.153,3.557,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.520039,0.00221855,0.434448 kka2_1:2_N195R,kka2_1:2_195,Kka2,kka2_1:2,P00552,0.434458,NO,195,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-0.836,-3.572,2.736,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.295029,0.00276134,0.434458 beta-lactamase_625_L137H,beta-lactamase_625_137,TEM-1,beta-lactamase_625,P62593,0.43446,NO,137,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.03,-4.934,3.904,,,H,A,0.55,-0.38,1.5,,42.31,HHP,-1.58933,0.213352,0.00278599,0.43446 kka2_1:1_E230K,kka2_1:1_230,Kka2,kka2_1:1,P00552,0.434469,NO,230,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.672,-3.648,0.976,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.520039,0.00920051,0.434469 kka2_1:4_D183M,kka2_1:4_183,Kka2,kka2_1:4,P00552,0.434615,NO,183,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.204,-4.843,3.639,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.168804,0.00426304,0.434615 beta-lactamase_156_M115W,beta-lactamase_156_115,TEM-1,beta-lactamase_156,P62593,0.434652,NO,115,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.389,-5.031,3.642,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.111618,0.0034337,0.434652 kka2_1:8_R253P,kka2_1:8_253,Kka2,kka2_1:8,P00552,0.434727,NO,253,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.356,-3.924,2.568,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.100394,0.0144195,0.434727 kka2_1:8_R253P,kka2_1:8_253,Kka2,kka2_1:8,P00552,0.434727,NO,253,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.356,-3.924,2.568,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.100394,0.0144195,0.434727 beta-lactamase_625_F64W,beta-lactamase_625_64,TEM-1,beta-lactamase_625,P62593,0.43476,NO,64,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-0.841,-4.422,3.581,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.213352,0.000947691,0.43476 PSD95pdz3_I341W,PSD95pdz3_341,PSD95pdz3,PSD95pdz3,P31016,0.43477,NO,341,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.63,-5.004,3.374,5.73946,,,,,10.3187,,,,HHH,-1.50033,0.0758425,0.000824087,0.43477 kka2_1:2_A224Y,kka2_1:2_224,Kka2,kka2_1:2,P00552,0.434776,NO,224,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.977,-4.257,3.28,,,H,A,0.46,-1.26,1.646,,63.64,HHP,-1.41033,0.295029,0.00352047,0.434776 E1_Ubiquitin_L43N,E1_Ubiquitin_43,Uba1,E1_Ubiquitin,P0CG63,0.435013,NO,43,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.188,-3.782,2.594,,,E,B,,-1.17,,,,BHH,-1.30733,0.18783,0.00190185,0.435013 kka2_1:1_I29A,kka2_1:1_29,Kka2,kka2_1:1,P00552,0.435085,NO,29,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.692,-3.281,1.589,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.520039,0.00619521,0.435085 beta-lactamase_625_Y95T,beta-lactamase_625_95,TEM-1,beta-lactamase_625,P62593,0.435135,NO,95,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-1.715,-3.697,1.982,,0.122,,b,0.21,-0.37,3.355,,77.62,BHP,-2.16167,0.213352,0.00479449,0.435135 beta-lactamase_0_T179W,beta-lactamase_0_179,TEM-1,beta-lactamase_0,P62593,0.43516,NO,179,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.085,-5.211,4.126,,,E,B,0.22,-1.38,0.367,,73.08,PPH,-1.557,0.0500837,0.00226045,0.43516 kka2_1:2_F133S,kka2_1:2_133,Kka2,kka2_1:2,P00552,0.435192,NO,133,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-0.871,-3.662,2.791,,0.178,.,B,0.58,0.43,1.999,,42.42,OHA,-0.871667,0.295029,0.00182168,0.435192 beta-lactamase_R220W,beta-lactamase_220,TEM-1,beta-lactamase,P62593,0.435222,NO,220,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-0.942,-5.348,4.406,5.65995,0.295,I,A,0.68,-0.76,2.164,,74.48,HBP,-1.33633,0.221079,0.00232421,0.435222 beta-lactamase_156_R202P,beta-lactamase_156_202,TEM-1,beta-lactamase_156,P62593,0.435232,NO,202,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.292,-3.859,2.567,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.111618,0.00321899,0.435232 kka2_1:4_A117Y,kka2_1:4_117,Kka2,kka2_1:4,P00552,0.435323,NO,117,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.828,-4.189,3.361,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.168804,0.00282984,0.435323 kka2_1:8_V83P,kka2_1:8_83,Kka2,kka2_1:8,P00552,0.43539,NO,83,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-2.567,-4.134,1.567,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.100394,0.00650486,0.43539 kka2_1:8_V83P,kka2_1:8_83,Kka2,kka2_1:8,P00552,0.43539,NO,83,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-2.567,-4.134,1.567,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.100394,0.00650486,0.43539 beta-lactamase_625_D48K,beta-lactamase_625_48,TEM-1,beta-lactamase_625,P62593,0.435413,NO,48,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.101,-3.448,2.347,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.213352,0.0027273,0.435413 beta-lactamase_A235Y,beta-lactamase_235,TEM-1,beta-lactamase,P62593,0.435413,NO,235,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.266,-4.294,3.028,4.83024,0.32,E,B,0.52,-0.86,1.344,,50,OHO,-0.89,0.221079,0.00493474,0.435413 kka2_1:1_Q61F,kka2_1:1_61,Kka2,kka2_1:1,P00552,0.435428,NO,61,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.982,-4.457,1.475,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.520039,0.00612092,0.435428 beta-lactamase_39_V42E,beta-lactamase_39_42,TEM-1,beta-lactamase_39,P62593,0.435443,NO,42,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.564,-3.88,2.316,,0.017,E,B,0.44,-0.51,1.86,,63.99,BHO,-1.042,0.0495842,0.00404515,0.435443 kka2_1:8_A215V,kka2_1:8_215,Kka2,kka2_1:8,P00552,0.435462,NO,215,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.968,-3.282,2.314,,0.039,E,B,1.04,-0.59,2.77,,50.38,HHA,-1.00467,0.100394,0.00529129,0.435462 kka2_1:8_A215V,kka2_1:8_215,Kka2,kka2_1:8,P00552,0.435462,NO,215,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.968,-3.282,2.314,,0.039,E,B,1.04,-0.59,2.77,,50.38,HHA,-1.00467,0.100394,0.00529129,0.435462 Ubiquitin_I23E,Ubiquitin_23,Uba1,Ubiquitin,P0CG48,0.435484,NO,23,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.325,-3.845,2.52,4.67534,,H,A,0.01,-0.93,0.515,,52.12,PHA,-1.54033,0.205827,0.000621252,0.435484 Ubiquitin_L8Y,Ubiquitin_8,Uba1,Ubiquitin,P0CG48,0.435484,NO,8,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.723,-4.009,2.286,5.28016,0.664,T,A,0.08,-0.34,0.664,,29.05,PHP,-1.51567,0.205827,0.000726165,0.435484 beta-lactamase_625_R242E,beta-lactamase_625_242,TEM-1,beta-lactamase_625,P62593,0.435612,NO,242,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.213352,0.00452879,0.435612 kka2_1:1_L170F,kka2_1:1_170,Kka2,kka2_1:1,P00552,0.435673,NO,170,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.28,-3.877,2.597,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.520039,0.00730791,0.435673 gb1_N261W,gb1_261,gb1,gb1,P06654,0.435756,NO,261,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-1.863,-5.194,3.331,,,,,,,1.191,,44.87,HPA,-2.16033,0.177985,0.0061875,0.435756 gb1_V265S,gb1_265,gb1,gb1,P06654,0.435756,NO,265,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.843,-3.102,1.259,,,,,,,0.402,,11.83,OHA,-1.64567,0.177985,0.00360613,0.435756 gb1_V280E,gb1_280,gb1,gb1,P06654,0.435756,NO,280,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.764,-3.487,1.723,,,,,,,0.874,,35.71,PHP,-1.63733,0.177985,0.00321577,0.435756 kka2_1:2_A71D,kka2_1:2_71,Kka2,kka2_1:2,P00552,0.435805,NO,71,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.824,-3.702,1.878,,0.553,H,A,0.46,0.08,9.788,,64.39,HHP,-1.74033,0.295029,0.00727707,0.435805 beta-lactamase_2500_L160N,beta-lactamase_2500_160,TEM-1,beta-lactamase_2500,P62593,0.435889,NO,160,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.977,-4.165,3.188,,0.022,,B,0.55,-0.6,0.895,,44.41,BHA,-0.936,0.361275,0.00193775,0.435889 kka2_1:1_H162L,kka2_1:1_162,Kka2,kka2_1:1,P00552,0.436012,NO,162,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-2.319,-3.554,1.235,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.520039,0.00616145,0.436012 beta-lactamase_2500_S104H,beta-lactamase_2500_104,TEM-1,beta-lactamase_2500,P62593,0.436014,NO,104,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.015,-4.582,3.567,,0.04,,b,0.27,0.57,1.133,,63.29,HPO,-1.05267,0.361275,0.00218083,0.436014 kka2_1:1_T125V,kka2_1:1_125,Kka2,kka2_1:1,P00552,0.436023,NO,125,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.622,-2.85,0.228,,0.791,T,A,0.22,0.33,1.972,,92.05,BPH,-1.56933,0.520039,0.00821755,0.436023 beta-lactamase_625_T69M,beta-lactamase_625_69,TEM-1,beta-lactamase_625,P62593,0.436045,NO,69,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-0.973,-4.54,3.567,,,G,A,0.22,-1.24,2.716,,93.01,PPH,-1.01833,0.213352,0.00127498,0.436045 beta-lactamase_625_G236C,beta-lactamase_625_236,TEM-1,beta-lactamase_625,P62593,0.436057,NO,236,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.784,-4.991,4.207,,0.241,,b,0.29,-0.59,3.506,,64.69,HOO,-1.025,0.213352,0.00162372,0.436057 beta-lactamase_2500_I93F,beta-lactamase_2500_93,TEM-1,beta-lactamase_2500,P62593,0.436082,NO,93,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.401,-3.88,2.479,,0.128,E,B,0.48,0.44,19.374,19.374,67.83,BHB,-1.873,0.361275,0.00527066,0.436082 kka2_1:2_W236Q,kka2_1:2_236,Kka2,kka2_1:2,P00552,0.436098,NO,236,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-1.363,-4.284,2.921,,0.303,H,A,1.51,-0.76,5.58,,48.48,AHH,-1.81267,0.295029,0.0088796,0.436098 kka2_1:2_D216L,kka2_1:2_216,Kka2,kka2_1:2,P00552,0.436099,NO,216,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.785,-3.835,3.05,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.295029,0.00229969,0.436099 beta-lactamase_625_R220M,beta-lactamase_625_220,TEM-1,beta-lactamase_625,P62593,0.4361,NO,220,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-0.942,-4.506,3.564,,0.295,I,A,1.2,-0.76,5.086,,74.48,HBP,-1.33633,0.213352,0.00232421,0.4361 kka2_1:2_R140Y,kka2_1:2_140,Kka2,kka2_1:2,P00552,0.436104,NO,140,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.351,-4.311,2.96,,0.12,H,A,1.2,0.2,0.352,,53.03,BBH,-1.885,0.295029,0.00430167,0.436104 kka2_1:1_Q26D,kka2_1:1_26,Kka2,kka2_1:1,P00552,0.436135,NO,26,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.18,-3.048,0.868,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.520039,0.00708962,0.436135 beta-lactamase_2500_A215F,beta-lactamase_2500_215,TEM-1,beta-lactamase_2500,P62593,0.436186,NO,215,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.503,-4.278,2.775,,,,a,0.46,-0.93,3.516,,74.48,HHO,-1.42633,0.361275,0.00544007,0.436186 kka2_1:1_G213D,kka2_1:1_213,Kka2,kka2_1:1,P00552,0.436195,NO,213,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.596,-3.497,2.901,,,E,b,0.29,-0.4,,,,HOH,-0.920333,0.520039,0.00187654,0.436195 beta-lactamase_625_D83L,beta-lactamase_625_83,TEM-1,beta-lactamase_625,P62593,0.436209,NO,83,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.066,-3.79,2.724,,0.354,H,A,0.75,0.22,0.239,,48.95,HAH,-1.34733,0.213352,0.00205968,0.436209 beta-lactamase_L191N,beta-lactamase_191,TEM-1,beta-lactamase,P62593,0.436209,NO,191,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.087,-4.164,3.077,5.72226,,H,A,1.07,0.09,1.23,,63.29,BHH,-1.445,0.221079,0.00263549,0.436209 beta-lactamase_V31W,beta-lactamase_31,TEM-1,beta-lactamase,P62593,0.436209,NO,31,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.822,-5.287,3.465,5.43781,,H,A,2.78,-0.46,2.885,,73.78,BHB,-2.03767,0.221079,0.00478065,0.436209 Pab1_N127D,Pab1_127,Pab1,Pab1,P04147,0.43622,NO,127,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-1.079,-2.836,1.757,,0.138,E,B,1.05,-0.51,,,,OPH,-1.13633,0.175299,0.000805159,0.43622 kka2_1:4_H162Q,kka2_1:4_162,Kka2,kka2_1:4,P00552,0.436226,NO,162,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-2.319,-3.703,1.384,,0.071,G,A,0.17,1.01,3.187,,64.39,ABP,-2.02067,0.168804,0.00616145,0.436226 kka2_1:2_D90G,kka2_1:2_90,Kka2,kka2_1:2,P00552,0.436241,NO,90,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.459,-3.503,1.044,,0.104,E,B,0.75,0.73,6.085,,64.39,BAH,-1.72833,0.295029,0.00583842,0.436241 beta-lactamase_625_L192Q,beta-lactamase_625_192,TEM-1,beta-lactamase_625,P62593,0.436308,NO,192,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.254,-4.246,2.992,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.213352,0.00558728,0.436308 kka2_1:1_E111S,kka2_1:1_111,Kka2,kka2_1:1,P00552,0.436341,NO,111,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.28,-2.706,0.426,,0.155,H,A,1.52,-1.14,15.716,15.716,65.53,HAB,-2.27833,0.520039,0.00746789,0.436341 kka2_1:1_E111W,kka2_1:1_111,Kka2,kka2_1:1,P00552,0.436341,NO,111,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.28,-5.588,3.308,,0.155,H,A,1.52,-1.14,15.716,15.716,65.53,HAB,-2.27833,0.520039,0.00746789,0.436341 beta-lactamase_625_V78E,beta-lactamase_625_78,TEM-1,beta-lactamase_625,P62593,0.436359,NO,78,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.459,-3.911,2.452,,,H,A,0.44,-0.47,2.045,,63.64,HHH,-1.17833,0.213352,0.00492501,0.436359 kka2_1:2_F37I,kka2_1:2_37,Kka2,kka2_1:2,P00552,0.436368,NO,37,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.427,-3.594,2.167,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.295029,0.00586193,0.436368 beta-lactamase_2500_L89K,beta-lactamase_2500_89,TEM-1,beta-lactamase_2500,P62593,0.436386,NO,89,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.096,-3.669,2.573,,0.168,T,A,0.55,0.63,2.066,,64.34,PHO,-1.75767,0.361275,0.00207068,0.436386 kka2_1:1_G181A,kka2_1:1_181,Kka2,kka2_1:1,P00552,0.436414,NO,181,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-2.698,-2.631,-0.067,,0.379,S,B,0.75,0.78,15.356,15.356,71.59,AOA,-2.21,0.520039,0.00728319,0.436414 beta-lactamase_625_C121R,beta-lactamase_625_121,TEM-1,beta-lactamase_625,P62593,0.436441,NO,121,C,R,CR,Special,PositiveCharge,5.07,6.34148,1.27148,180,121,174,53,108.5,173.4,64.9,-0.953,-2.762,1.809,,,H,A,0.46,-0.81,1.143,,63.29,HOP,-1.46767,0.213352,0.000744322,0.436441 beta-lactamase_2500_E119T,beta-lactamase_2500_119,TEM-1,beta-lactamase_2500,P62593,0.436444,NO,119,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.412,-3.526,2.114,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.361275,0.00386966,0.436444 kka2_1:4_D159M,kka2_1:4_159,Kka2,kka2_1:4,P00552,0.436447,NO,159,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.82,-4.992,4.172,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.168804,0.0030485,0.436447 beta-lactamase_2500_L49H,beta-lactamase_2500_49,TEM-1,beta-lactamase_2500,P62593,0.436465,NO,49,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.897,-4.794,2.897,,0.131,T,A,0.55,0.04,6.681,,64.69,AHP,-1.99233,0.361275,0.00401477,0.436465 Pab1_L142S,Pab1_142,Pab1,Pab1,P04147,0.436658,NO,142,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.039,-3.428,2.389,,0.007,H,A,0.84,-0.65,,,,HHH,-1.487,0.175299,0.000335477,0.436658 kka2_1:1_A191H,kka2_1:1_191,Kka2,kka2_1:1,P00552,0.43671,NO,191,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.831,-4.743,3.912,,,.,b,0.46,-0.94,0.53,,50,AHO,-0.868667,0.520039,0.00338807,0.43671 beta-lactamase_39_S68I,beta-lactamase_39_68,TEM-1,beta-lactamase_39,P62593,0.436739,NO,68,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-0.913,-3.834,2.921,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.0495842,0.000800065,0.436739 beta-lactamase_625_L219W,beta-lactamase_625_219,TEM-1,beta-lactamase_625,P62593,0.436877,NO,219,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.313,-5.183,3.87,,,I,A,0.55,-0.51,5.627,,74.48,HHB,-1.21533,0.213352,0.00664345,0.436877 beta-lactamase_V117E,beta-lactamase_117,TEM-1,beta-lactamase,P62593,0.436965,NO,117,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.53,-3.909,2.379,5.33594,,H,A,1.19,-0.34,1.182,,65.03,PHB,-1.741,0.221079,0.00467906,0.436965 kka2_1:1_P45V,kka2_1:1_45,Kka2,kka2_1:1,P00552,0.436971,NO,45,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.774,-3.689,1.915,,0.669,.,B,0.52,-0.76,4.882,,71.59,BOH,-2.152,0.520039,0.00590481,0.436971 beta-lactamase_2500_P105I,beta-lactamase_2500_105,TEM-1,beta-lactamase_2500,P62593,0.437003,NO,105,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.813,-4.008,3.195,,0.226,T,A,0.52,0.8,3.1,,63.29,POH,-1.01533,0.361275,0.0011981,0.437003 kka2_1:4_W236H,kka2_1:4_236,Kka2,kka2_1:4,P00552,0.437021,NO,236,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-1.363,-4.78,3.417,,0.303,H,A,0.47,-0.76,2.277,,48.48,AHH,-1.81267,0.168804,0.0088796,0.437021 kka2_1:4_W69D,kka2_1:4_69,Kka2,kka2_1:4,P00552,0.437096,NO,69,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-0.859,-4.17,3.311,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.168804,0.0012874,0.437096 beta-lactamase_2500_Q276D,beta-lactamase_2500_276,TEM-1,beta-lactamase_2500,P62593,0.43716,NO,276,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.361275,0.0191712,0.43716 beta-lactamase_2500_L192Q,beta-lactamase_2500_192,TEM-1,beta-lactamase_2500,P62593,0.437177,NO,192,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.254,-4.246,2.992,,0.095,H,A,0.55,0.35,1.902,,60.14,HHP,-1.41833,0.361275,0.00558728,0.437177 kka2_1:2_I228L,kka2_1:2_228,Kka2,kka2_1:2,P00552,0.437178,NO,228,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.142,-1.811,0.669,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.295029,0.00458834,0.437178 beta-lactamase_156_I125F,beta-lactamase_156_125,TEM-1,beta-lactamase_156,P62593,0.43718,NO,125,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.441,-3.841,2.4,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.111618,0.00383964,0.43718 kka2_1:2_P179A,kka2_1:2_179,Kka2,kka2_1:2,P00552,0.437329,NO,179,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.974,-2.519,1.545,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.295029,0.00298346,0.437329 kka2_1:2_P128C,kka2_1:2_128,Kka2,kka2_1:2,P00552,0.437366,NO,128,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.922,-4.968,3.046,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.295029,0.00774689,0.437366 kka2_1:4_A237E,kka2_1:4_237,Kka2,kka2_1:4,P00552,0.437396,NO,237,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.12,-3.758,1.638,,0.068,H,A,0.46,-0.71,2.444,,92.05,HHA,-2.10433,0.168804,0.012257,0.437396 beta-lactamase_625_W208C,beta-lactamase_625_208,TEM-1,beta-lactamase_625,P62593,0.437603,NO,208,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-0.818,-4.862,4.044,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.213352,0.00126609,0.437603 beta-lactamase_2500_E87C,beta-lactamase_2500_87,TEM-1,beta-lactamase_2500,P62593,0.437607,NO,87,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.421,-5.162,3.741,,0.048,,B,1.04,0.92,17.923,17.923,64.69,PAP,-1.969,0.361275,0.00337888,0.437607 beta-lactamase_625_A123M,beta-lactamase_625_123,TEM-1,beta-lactamase_625,P62593,0.437621,NO,123,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.834,-4.443,3.609,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.213352,0.0010157,0.437621 kka2_1:2_L57K,kka2_1:2_57,Kka2,kka2_1:2,P00552,0.43769,NO,57,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.898,-3.894,1.996,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.295029,0.00723769,0.43769 kka2_1:1_D157S,kka2_1:1_157,Kka2,kka2_1:1,P00552,0.437713,NO,157,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.993,-2.619,1.626,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.520039,0.0042313,0.437713 kka2_1:1_W236A,kka2_1:1_236,Kka2,kka2_1:1,P00552,0.437736,NO,236,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-1.363,-2.534,1.171,,0.303,H,A,1.51,-0.76,12.263,12.263,48.48,AHH,-1.81267,0.520039,0.0088796,0.437736 kka2_1:2_G245A,kka2_1:2_245,Kka2,kka2_1:2,P00552,0.437842,NO,245,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.812,-2.418,1.606,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.295029,0.00683899,0.437842 kka2_1:1_H124I,kka2_1:1_124,Kka2,kka2_1:1,P00552,0.437845,NO,124,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-0.84,-4.039,3.199,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.520039,0.00211296,0.437845 kka2_1:1_H124K,kka2_1:1_124,Kka2,kka2_1:1,P00552,0.437845,NO,124,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-0.84,-3.485,2.645,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.520039,0.00211296,0.437845 beta-lactamase_2500_E46C,beta-lactamase_2500_46,TEM-1,beta-lactamase_2500,P62593,0.437941,NO,46,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.94,-3.249,1.309,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.361275,0.00427568,0.437941 kka2_1:1_V214M,kka2_1:1_214,Kka2,kka2_1:1,P00552,0.437941,NO,214,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.261,-4.2,2.939,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.520039,0.00692782,0.437941 beta-lactamase_2500_R159L,beta-lactamase_2500_159,TEM-1,beta-lactamase_2500,P62593,0.437965,NO,159,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-0.94,-3.407,2.467,,0.316,,B,1.2,-0.55,2.341,,64.34,PBH,-1.011,0.361275,0.00108472,0.437965 beta-lactamase_K30P,beta-lactamase_30,TEM-1,beta-lactamase,P62593,0.438031,NO,30,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-2.307,-3.871,1.564,5.30605,0.142,H,A,1.82,-0.65,2.434,,93.01,HBH,-2.32833,0.221079,0.00448593,0.438031 kka2_1:2_P12I,kka2_1:2_12,Kka2,kka2_1:2,P00552,0.438054,NO,12,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.853,-3.96,3.107,,,.,B,0.52,1.25,0.261,,48.11,POH,-1.80767,0.295029,0.00500011,0.438054 beta-lactamase_625_V260M,beta-lactamase_625_260,TEM-1,beta-lactamase_625,P62593,0.438072,NO,260,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.213352,0.00471757,0.438072 kka2_1:4_R211W,kka2_1:4_211,Kka2,kka2_1:4,P00552,0.438099,NO,211,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-0.899,-2.964,2.065,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.168804,0.00204888,0.438099 beta-lactamase_625_W208E,beta-lactamase_625_208,TEM-1,beta-lactamase_625,P62593,0.438131,NO,208,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-0.818,-3.89,3.072,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.213352,0.00126609,0.438131 kka2_1:1_A129V,kka2_1:1_129,Kka2,kka2_1:1,P00552,0.43815,NO,129,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.656,-3.024,1.368,,0.845,G,A,0.46,0.72,19.686,19.686,92.05,OHP,-1.99,0.520039,0.00726862,0.43815 kka2_1:1_F203V,kka2_1:1_203,Kka2,kka2_1:1,P00552,0.438171,NO,203,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-0.911,-3.287,2.376,,0.26,E,B,0.58,-0.92,7.323,,63.64,BHP,-1.34167,0.520039,0.00318738,0.438171 kka2_1:2_P179W,kka2_1:2_179,Kka2,kka2_1:2,P00552,0.438188,NO,179,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.974,-5.539,4.565,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.295029,0.00298346,0.438188 kka2_1:1_A119G,kka2_1:1_119,Kka2,kka2_1:1,P00552,0.438215,NO,119,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.073,-2.216,1.143,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.520039,0.00441074,0.438215 kka2_1:8_Y244K,kka2_1:8_244,Kka2,kka2_1:8,P00552,0.438292,NO,244,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-0.775,-3.71,2.935,,0.066,H,A,1.25,-0.64,,,,HHO,-1.41267,0.100394,0.00453187,0.438292 kka2_1:8_Y244K,kka2_1:8_244,Kka2,kka2_1:8,P00552,0.438292,NO,244,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-0.775,-3.71,2.935,,0.066,H,A,1.25,-0.64,,,,HHO,-1.41267,0.100394,0.00453187,0.438292 kka2_1:4_V198G,kka2_1:4_198,Kka2,kka2_1:4,P00552,0.438335,NO,198,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.719,-3.368,1.649,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.168804,0.00835002,0.438335 beta-lactamase_156_G240E,beta-lactamase_156_240,TEM-1,beta-lactamase_156,P62593,0.438391,NO,240,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.111618,0.00591201,0.438391 kka2_1:4_I207F,kka2_1:4_207,Kka2,kka2_1:4,P00552,0.438392,NO,207,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.175,-3.792,2.617,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.168804,0.00611824,0.438392 beta-lactamase_2500_G226L,beta-lactamase_2500_226,TEM-1,beta-lactamase_2500,P62593,0.438435,NO,226,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.461,-3.765,2.304,,0.701,T,l,0.29,-0.25,5.086,,74.48,HOH,-1.42933,0.361275,0.00665294,0.438435 kka2_1:2_W24M,kka2_1:2_24,Kka2,kka2_1:2,P00552,0.438535,NO,24,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-1.779,-3.383,1.604,,0.477,E,B,1.51,-0.21,2.666,,56.06,AHH,-2.24467,0.295029,0.00631564,0.438535 kka2_1:4_A117G,kka2_1:4_117,Kka2,kka2_1:4,P00552,0.43861,NO,117,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.828,-3.044,2.216,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.168804,0.00282984,0.43861 beta-lactamase_39_C121H,beta-lactamase_39_121,TEM-1,beta-lactamase_39,P62593,0.438709,NO,121,C,H,CH,Special,PositiveCharge,5.07,7.59,2.52,174,121,155,34,108.5,153.2,44.7,-0.953,-4.827,3.874,,,H,A,0.46,-0.81,7.644,,63.29,HOP,-1.46767,0.0495842,0.000744322,0.438709 kka2_1:1_I228S,kka2_1:1_228,Kka2,kka2_1:1,P00552,0.438781,NO,228,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.142,-3.711,2.569,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.520039,0.00458834,0.438781 kka2_1:1_I29D,kka2_1:1_29,Kka2,kka2_1:1,P00552,0.438793,NO,29,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.692,-3.047,1.355,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.520039,0.00619521,0.438793 beta-lactamase_625_L47W,beta-lactamase_625_47,TEM-1,beta-lactamase_625,P62593,0.438799,NO,47,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.876,-5.24,3.364,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.213352,0.00439844,0.438799 kka2_1:1_H135T,kka2_1:1_135,Kka2,kka2_1:1,P00552,0.438968,NO,135,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-1.331,-3.65,2.319,,0.071,.,a,0.17,0.65,3.574,,53.03,ABP,-1.77367,0.520039,0.00532566,0.438968 kka2_1:2_A237N,kka2_1:2_237,Kka2,kka2_1:2,P00552,0.438979,NO,237,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.12,-4.131,2.011,,0.068,H,A,0.46,-0.71,2.369,,92.05,HHA,-2.10433,0.295029,0.012257,0.438979 kka2_1:4_D101S,kka2_1:4_101,Kka2,kka2_1:4,P00552,0.438984,NO,101,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.028,-3.266,2.238,,0.213,E,B,0.75,-1.24,8.707,,63.64,PAH,-1.534,0.168804,0.00423361,0.438984 beta-lactamase_2500_R273Y,beta-lactamase_2500_273,TEM-1,beta-lactamase_2500,P62593,0.439078,NO,273,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.314,-4.336,2.022,,0.564,H,A,1.2,1.57,19.943,19.943,73.78,ABP,-1.841,0.361275,0.0077952,0.439078 beta-lactamase_2500_R257H,beta-lactamase_2500_257,TEM-1,beta-lactamase_2500,P62593,0.439109,NO,257,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.361275,0.00756629,0.439109 beta-lactamase_625_T187R,beta-lactamase_625_187,TEM-1,beta-lactamase_625,P62593,0.439174,NO,187,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.401,-3.885,2.484,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.213352,0.00491782,0.439174 kka2_1:8_V113D,kka2_1:8_113,Kka2,kka2_1:8,P00552,0.4392,NO,113,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.233,-4.075,2.842,,0.008,H,A,1.48,-1.17,1.254,,52.27,BHP,-2.08367,0.100394,0.00650191,0.4392 kka2_1:8_V113D,kka2_1:8_113,Kka2,kka2_1:8,P00552,0.4392,NO,113,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.233,-4.075,2.842,,0.008,H,A,1.48,-1.17,1.254,,52.27,BHP,-2.08367,0.100394,0.00650191,0.4392 kka2_1:4_D159C,kka2_1:4_159,Kka2,kka2_1:4,P00552,0.439231,NO,159,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.82,-5.15,4.33,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.168804,0.0030485,0.439231 kka2_1:2_A229V,kka2_1:2_229,Kka2,kka2_1:2,P00552,0.439255,NO,229,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.739,-2.471,0.732,,0.32,H,A,0.46,-0.7,6.549,,63.64,HHA,-1.851,0.295029,0.00942138,0.439255 beta-lactamase_2500_V82E,beta-lactamase_2500_82,TEM-1,beta-lactamase_2500,P62593,0.439257,NO,82,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.325,-3.751,2.426,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.361275,0.00397046,0.439257 beta-lactamase_2500_T179P,beta-lactamase_2500_179,TEM-1,beta-lactamase_2500,P62593,0.439308,NO,179,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.085,-3.739,2.654,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.361275,0.00226045,0.439308 kka2_1:2_L67V,kka2_1:2_67,Kka2,kka2_1:2,P00552,0.439324,NO,67,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.741,-2.882,2.141,,0.007,H,A,1.59,-0.66,,,,BHP,-1.42867,0.295029,0.00102787,0.439324 kka2_1:1_E182K,kka2_1:1_182,Kka2,kka2_1:1,P00552,0.439327,NO,182,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.516,-3.472,1.956,,0.326,,B,1.52,0.75,14.547,14.547,65.53,OAA,-1.806,0.520039,0.00641548,0.439327 beta-lactamase_2500_E62K,beta-lactamase_2500_62,TEM-1,beta-lactamase_2500,P62593,0.439479,NO,62,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.193,-3.246,2.053,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.361275,0.00264802,0.439479 kka2_1:1_F240H,kka2_1:1_240,Kka2,kka2_1:1,P00552,0.439507,NO,240,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-0.911,-4.571,3.66,,,H,A,1.62,-1.21,5.798,,50.38,BHH,-1.67267,0.520039,0.00552543,0.439507 kka2_1:1_E160H,kka2_1:1_160,Kka2,kka2_1:1,P00552,0.439548,NO,160,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.683,-4.581,2.898,,0.989,G,A,1.04,2.28,0.273,,71.59,AAA,-1.36133,0.520039,0.00935762,0.439548 beta-lactamase_625_I93S,beta-lactamase_625_93,TEM-1,beta-lactamase_625,P62593,0.43957,NO,93,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.401,-3.663,2.262,,0.128,E,B,0.48,0.44,1.524,,67.83,BHB,-1.873,0.213352,0.00527066,0.43957 kka2_1:1_A144T,kka2_1:1_144,Kka2,kka2_1:1,P00552,0.439581,NO,144,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.859,-3.269,2.41,,,H,A,0.46,0.21,0.842,,52.65,BHB,-1.72933,0.520039,0.00231095,0.439581 beta-lactamase_625_L218T,beta-lactamase_625_218,TEM-1,beta-lactamase_625,P62593,0.439631,NO,218,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.391,-2.536,1.145,,,I,b,0.55,-0.53,17.202,17.202,74.48,OHH,-1.58867,0.213352,0.00618274,0.439631 kka2_1:8_R66V,kka2_1:8_66,Kka2,kka2_1:8,P00552,0.439653,NO,66,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-0.922,-3.78,2.858,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.100394,0.00161025,0.439653 kka2_1:8_R66V,kka2_1:8_66,Kka2,kka2_1:8,P00552,0.439653,NO,66,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-0.922,-3.78,2.858,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.100394,0.00161025,0.439653 beta-lactamase_0_T178M,beta-lactamase_0_178,TEM-1,beta-lactamase_0,P62593,0.439735,NO,178,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-0.791,-4.48,3.689,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.0500837,0.000684366,0.439735 beta-lactamase_2500_A230L,beta-lactamase_2500_230,TEM-1,beta-lactamase_2500,P62593,0.439738,NO,230,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.154,-3.416,2.262,,0.01,E,B,0.46,-1.17,1.171,,50,HHA,-1.079,0.361275,0.00516841,0.439738 kka2_1:1_E149W,kka2_1:1_149,Kka2,kka2_1:1,P00552,0.43983,NO,149,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.994,-5.569,3.575,,0.674,H,A,1.04,1.63,3.671,,71.59,HAH,-1.59667,0.520039,0.00803343,0.43983 beta-lactamase_2500_V72M,beta-lactamase_2500_72,TEM-1,beta-lactamase_2500,P62593,0.439895,NO,72,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.658,-4.404,2.746,,,H,A,0.44,-1.03,2.079,,65.73,BHH,-1.32167,0.361275,0.00501194,0.439895 kka2_1:1_A56W,kka2_1:1_56,Kka2,kka2_1:1,P00552,0.439922,NO,56,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.083,-5.608,3.525,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.520039,0.00717715,0.439922 kka2_1:2_S104P,kka2_1:2_104,Kka2,kka2_1:2,P00552,0.439952,NO,104,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.436,-3.932,2.496,,0.536,T,A,0.27,-1.11,5.49,,63.64,HPP,-1.91433,0.295029,0.00555207,0.439952 kka2_1:2_F133M,kka2_1:2_133,Kka2,kka2_1:2,P00552,0.439971,NO,133,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-0.871,-4.327,3.456,,0.178,.,B,0.58,0.43,1.999,,42.42,OHA,-0.871667,0.295029,0.00182168,0.439971 beta-lactamase_2500_M66G,beta-lactamase_2500_66,TEM-1,beta-lactamase_2500,P62593,0.439977,NO,66,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.362,-3.751,2.389,,0.013,,A,0.55,-0.7,0.502,,73.08,OHH,-1.49567,0.361275,0.00412876,0.439977 kka2_1:2_I141D,kka2_1:2_141,Kka2,kka2_1:2,P00552,0.440033,NO,141,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.495,-4.166,2.671,,0.068,H,A,0.48,-0.01,0.819,,92.05,BHA,-1.689,0.295029,0.00744745,0.440033 beta-lactamase_2500_L135R,beta-lactamase_2500_135,TEM-1,beta-lactamase_2500,P62593,0.440098,NO,135,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.002,-4.002,3,,0.117,H,A,0.55,-0.58,0.795,,43.71,PHH,-1.03767,0.361275,0.00244423,0.440098 kka2_1:1_L39D,kka2_1:1_39,Kka2,kka2_1:1,P00552,0.440286,NO,39,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.223,-4.127,2.904,,,E,B,0.55,-1.21,0.925,,71.59,BHP,-1.69167,0.520039,0.00493618,0.440286 kka2_1:2_R145T,kka2_1:2_145,Kka2,kka2_1:2,P00552,0.440384,NO,145,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.804,-3.648,1.844,,0.346,H,A,1.2,1.23,7.961,,63.64,HBP,-1.88033,0.295029,0.00846663,0.440384 kka2_1:2_L70A,kka2_1:2_70,Kka2,kka2_1:2,P00552,0.440442,NO,70,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.017,-3.191,2.174,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.295029,0.00411884,0.440442 beta-lactamase_2500_S104I,beta-lactamase_2500_104,TEM-1,beta-lactamase_2500,P62593,0.440448,NO,104,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.015,-3.786,2.771,,0.04,,b,0.27,0.57,1.133,,63.29,HPO,-1.05267,0.361275,0.00218083,0.440448 Pab1_F168L,Pab1_168,Pab1,Pab1,P04147,0.440477,NO,168,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.269,-2.829,1.56,,,,,,,0.789,,56.33,OHO,-1.10033,0.175299,0.00064061,0.440477 kka2_1:2_G99F,kka2_1:2_99,Kka2,kka2_1:2,P00552,0.440578,NO,99,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.596,-4.32,3.724,,0.368,S,g,0.29,-0.87,,,,OOP,-1.63067,0.295029,0.00186055,0.440578 kka2_1:2_F256E,kka2_1:2_256,Kka2,kka2_1:2,P00552,0.440614,NO,256,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.49,-3.921,2.431,,,H,A,0.58,-0.78,1.653,,53.03,HHH,-1.423,0.295029,0.0132841,0.440614 beta-lactamase_625_G114R,beta-lactamase_625_114,TEM-1,beta-lactamase_625,P62593,0.440747,NO,114,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.094,-2.891,1.797,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.213352,0.00224919,0.440747 beta-lactamase_625_G249A,beta-lactamase_625_249,TEM-1,beta-lactamase_625,P62593,0.440815,NO,249,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.213352,0.00220169,0.440815 kka2_1:2_L94E,kka2_1:2_94,Kka2,kka2_1:2,P00552,0.440881,NO,94,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.618,-3.883,2.265,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.295029,0.00520888,0.440881 beta-lactamase_2500_P105G,beta-lactamase_2500_105,TEM-1,beta-lactamase_2500,P62593,0.440917,NO,105,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.813,-3.321,2.508,,0.226,T,A,0.52,0.8,3.1,,63.29,POH,-1.01533,0.361275,0.0011981,0.440917 kka2_1:4_S204L,kka2_1:4_204,Kka2,kka2_1:4,P00552,0.441033,NO,204,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.353,-3.418,2.065,,0.144,E,A,0.27,-1.2,2.442,,65.53,HPO,-0.953333,0.168804,0.00881794,0.441033 kka2_1:4_D62Q,kka2_1:4_62,Kka2,kka2_1:4,P00552,0.441117,NO,62,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.591,-2.887,1.296,,0.262,H,A,0.29,0.08,14.756,14.756,64.39,PAA,-1.77833,0.168804,0.00744243,0.441117 kka2_1:8_V49W,kka2_1:8_49,Kka2,kka2_1:8,P00552,0.441189,NO,49,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.614,-5.38,3.766,,,E,B,1.48,-0.77,1.31,,64.39,HHB,-1.3,0.100394,0.00615685,0.441189 kka2_1:8_V49W,kka2_1:8_49,Kka2,kka2_1:8,P00552,0.441189,NO,49,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.614,-5.38,3.766,,,E,B,1.48,-0.77,1.31,,64.39,HHB,-1.3,0.100394,0.00615685,0.441189 beta-lactamase_2500_L218C,beta-lactamase_2500_218,TEM-1,beta-lactamase_2500,P62593,0.441242,NO,218,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.391,-4.928,3.537,,,I,b,0.55,-0.53,9.151,9.151,74.48,OHH,-1.58867,0.361275,0.00618274,0.441242 kka2_1:8_G205Q,kka2_1:8_205,Kka2,kka2_1:8,P00552,0.441279,NO,205,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.596,-4.153,3.557,,,E,b,0.75,-1.05,,,,POH,-1.09933,0.100394,0.00221855,0.441279 kka2_1:8_G205Q,kka2_1:8_205,Kka2,kka2_1:8,P00552,0.441279,NO,205,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.596,-4.153,3.557,,,E,b,0.75,-1.05,,,,POH,-1.09933,0.100394,0.00221855,0.441279 kka2_1:1_A71T,kka2_1:1_71,Kka2,kka2_1:1,P00552,0.441304,NO,71,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.824,-2.666,0.842,,0.553,H,A,0.46,0.08,9.788,,64.39,HHP,-1.74033,0.520039,0.00727707,0.441304 beta-lactamase_625_A235R,beta-lactamase_625_235,TEM-1,beta-lactamase_625,P62593,0.441326,NO,235,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.266,-3.887,2.621,,0.32,E,B,0.46,-0.86,0.281,,50,OHO,-0.89,0.213352,0.00493474,0.441326 kka2_1:1_Q4C,kka2_1:1_4,Kka2,kka2_1:1,P00552,0.441326,NO,4,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.361,-4.857,2.496,,,,,,,5.615,,71.59,APA,-1.95533,0.520039,0.00239179,0.441326 beta-lactamase_625_G141W,beta-lactamase_625_141,TEM-1,beta-lactamase_625,P62593,0.441361,NO,141,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.828,-5.233,4.405,,0.575,T,l,0.29,-0.28,0.198,,64.69,HOO,-1.08933,0.213352,0.0012419,0.441361 beta-lactamase_2500_L197Q,beta-lactamase_2500_197,TEM-1,beta-lactamase_2500,P62593,0.441363,NO,197,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.853,-4.122,3.269,,0.007,S,B,0.55,0.33,2.421,,60.14,HHP,-1.833,0.361275,0.00144602,0.441363 kka2_1:1_P45G,kka2_1:1_45,Kka2,kka2_1:1,P00552,0.441437,NO,45,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.774,-2.532,0.758,,0.669,.,B,0.52,-0.76,4.882,,71.59,BOH,-2.152,0.520039,0.00590481,0.441437 beta-lactamase_2500_P224W,beta-lactamase_2500_224,TEM-1,beta-lactamase_2500,P62593,0.441444,NO,224,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.893,-5.546,4.653,,0.383,,B,0.52,-0.3,2.666,,74.48,HOH,-1.26433,0.361275,0.00189564,0.441444 beta-lactamase_2500_G76V,beta-lactamase_2500_76,TEM-1,beta-lactamase_2500,P62593,0.441463,NO,76,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.189,-3.485,2.296,,,H,A,0.29,-0.67,1.012,,67.83,OOH,-1.22267,0.361275,0.00476637,0.441463 kka2_1:1_F264Y,kka2_1:1_264,Kka2,kka2_1:1,P00552,0.441487,NO,264,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.02,-2.016,0.996,,0.296,.,?,0.58,0.02,2.303,,71.59,HHNA,-0.9655,0.520039,,0.441487 beta-lactamase_2500_G114T,beta-lactamase_2500_114,TEM-1,beta-lactamase_2500,P62593,0.441489,NO,114,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.094,-2.276,1.182,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.361275,0.00224919,0.441489 kka2_1:2_H162I,kka2_1:2_162,Kka2,kka2_1:2,P00552,0.441518,NO,162,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-2.319,-4.138,1.819,,0.071,G,A,0.17,1.01,3.187,,64.39,ABP,-2.02067,0.295029,0.00616145,0.441518 kka2_1:2_F240T,kka2_1:2_240,Kka2,kka2_1:2,P00552,0.441531,NO,240,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-0.911,-3.673,2.762,,,H,A,0.58,-1.21,0.373,,50.38,BHH,-1.67267,0.295029,0.00552543,0.441531 PSD95pdz3_A375E,PSD95pdz3_375,PSD95pdz3,PSD95pdz3,P31016,0.441837,NO,375,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.307,-3.122,1.815,5.05512,,,,,13.888,,,,PHH,-1.43767,0.0758425,0.000356809,0.441837 kka2_1:4_A224P,kka2_1:4_224,Kka2,kka2_1:4,P00552,0.441897,NO,224,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.977,-3.784,2.807,,,H,A,0.46,-1.26,0.93,,63.64,HHP,-1.41033,0.168804,0.00352047,0.441897 beta-lactamase_625_K190P,beta-lactamase_625_190,TEM-1,beta-lactamase_625,P62593,0.441946,NO,190,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.994,-3.086,1.092,,0.371,H,A,2.34,0.16,29.753,29.753,77.62,BBH,-1.64167,0.213352,0.00574527,0.441946 beta-lactamase_0_C121V,beta-lactamase_0_121,TEM-1,beta-lactamase_0,P62593,0.441984,NO,121,C,V,CV,Special,Hydrophobic,5.07,5.60847,0.538465,192,121,117,-4,108.5,140,31.5,-0.953,-3.371,2.418,,,H,A,0.46,-0.81,3.302,,63.29,HOP,-1.46767,0.0500837,0.000744322,0.441984 beta-lactamase_2500_L120F,beta-lactamase_2500_120,TEM-1,beta-lactamase_2500,P62593,0.442007,NO,120,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.044,-2.785,1.741,,,H,A,0.55,-1.13,2.48,,64.69,AHO,-1.13633,0.361275,0.00143563,0.442007 beta-lactamase_A215L,beta-lactamase_215,TEM-1,beta-lactamase,P62593,0.442081,NO,215,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.503,-3.475,1.972,4.82164,,,a,0.75,-0.93,3.583,,74.48,HHO,-1.42633,0.221079,0.00544007,0.442081 kka2_1:4_I221N,kka2_1:4_221,Kka2,kka2_1:4,P00552,0.44209,NO,221,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.739,-4.276,2.537,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.168804,0.00945908,0.44209 kka2_1:1_L81I,kka2_1:1_81,Kka2,kka2_1:1,P00552,0.442176,NO,81,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.427,-1.722,0.295,,0.46,E,A,0.55,-0.14,0.374,,63.64,HHA,-1.50567,0.520039,0.00805839,0.442176 kka2_1:4_G205R,kka2_1:4_205,Kka2,kka2_1:4,P00552,0.4422,NO,205,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.596,-3.961,3.365,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.168804,0.00221855,0.4422 beta-lactamase_P20L,beta-lactamase_20,TEM-1,beta-lactamase,P62593,0.442208,NO,20,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.74,-3.264,1.524,,,,,,,0.368,,67.83,HOH,-1.765,0.221079,0.00235322,0.442208 kka2_1:2_L107Q,kka2_1:2_107,Kka2,kka2_1:2,P00552,0.442209,NO,107,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.238,-4.215,2.977,,0.197,,B,1.59,-1.1,2.68,,71.59,BHH,-2.143,0.295029,0.00561937,0.442209 kka2_1:4_L94A,kka2_1:4_94,Kka2,kka2_1:4,P00552,0.442281,NO,94,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.618,-3.195,1.577,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.168804,0.00520888,0.442281 beta-lactamase_2500_S266E,beta-lactamase_2500_266,TEM-1,beta-lactamase_2500,P62593,0.442328,NO,266,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.361275,0.0140785,0.442328 kka2_1:2_C77R,kka2_1:2_77,Kka2,kka2_1:2,P00552,0.442362,NO,77,C,R,CR,Special,PositiveCharge,5.07,6.34148,1.27148,180,121,174,53,108.5,173.4,64.9,-1.477,-4.125,2.648,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.295029,0.00441216,0.442362 PSD95pdz3_I338D,PSD95pdz3_338,PSD95pdz3,PSD95pdz3,P31016,0.442373,NO,338,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.63,-3.6,1.97,5.45113,,,,,13.0087,,,,HHP,-1.55767,0.0758425,0.000862587,0.442373 kka2_1:1_A137C,kka2_1:1_137,Kka2,kka2_1:1,P00552,0.442442,NO,137,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.156,-4.817,2.661,,0.029,H,A,0.46,0.34,1.323,,63.26,PHB,-2.559,0.520039,0.00515054,0.442442 kka2_1:4_P12Y,kka2_1:4_12,Kka2,kka2_1:4,P00552,0.44251,NO,12,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.853,-4.385,3.532,,,,B,0.52,1.25,0.843,,48.11,POH,-1.80767,0.168804,0.00500011,0.44251 beta-lactamase_2500_R41E,beta-lactamase_2500_41,TEM-1,beta-lactamase_2500,P62593,0.442529,NO,41,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-0.942,-3.241,2.299,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.361275,0.00123327,0.442529 kka2_1:8_F264H,kka2_1:8_264,Kka2,kka2_1:8,P00552,0.442627,NO,264,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.02,-4.405,3.385,,0.296,,?,1.62,0.02,1.553,,71.59,HHO,-0.9655,0.100394,,0.442627 kka2_1:8_F264H,kka2_1:8_264,Kka2,kka2_1:8,P00552,0.442627,NO,264,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.02,-4.405,3.385,,0.296,,?,1.62,0.02,1.553,,71.59,HHO,-0.9655,0.100394,,0.442627 kka2_1:2_P194S,kka2_1:2_194,Kka2,kka2_1:2,P00552,0.442633,NO,194,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.846,-2.623,1.777,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.295029,0.00314194,0.442633 kka2_1:2_D90Y,kka2_1:2_90,Kka2,kka2_1:2,P00552,0.442688,NO,90,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.459,-3.217,0.758,,0.104,E,B,0.75,0.73,6.085,,64.39,BAH,-1.72833,0.295029,0.00583842,0.442688 kka2_1:8_D190V,kka2_1:8_190,Kka2,kka2_1:8,P00552,0.442717,NO,190,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.708,-3.782,3.074,,0.213,S,b,0.29,-0.82,,,,OAH,-0.711667,0.100394,0.00247989,0.442717 kka2_1:8_D190V,kka2_1:8_190,Kka2,kka2_1:8,P00552,0.442717,NO,190,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.708,-3.782,3.074,,0.213,S,b,0.29,-0.82,,,,OAH,-0.711667,0.100394,0.00247989,0.442717 beta-lactamase_625_L219A,beta-lactamase_625_219,TEM-1,beta-lactamase_625,P62593,0.442791,NO,219,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.313,-3.187,1.874,,,I,A,0.55,-0.51,5.627,,74.48,HHB,-1.21533,0.213352,0.00664345,0.442791 kka2_1:2_I246Y,kka2_1:2_246,Kka2,kka2_1:2,P00552,0.442815,NO,246,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-2.008,-4.266,2.258,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.295029,0.0139479,0.442815 kka2_1:1_T146P,kka2_1:1_146,Kka2,kka2_1:1,P00552,0.442841,NO,146,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.978,-4.011,1.033,,0.281,H,A,0.82,0.78,2.105,,92.05,BPB,-1.96833,0.520039,0.00606474,0.442841 beta-lactamase_625_L100N,beta-lactamase_625_100,TEM-1,beta-lactamase_625,P62593,0.442856,NO,100,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.218,-4.207,2.989,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.213352,0.00413885,0.442856 beta-lactamase_625_A124L,beta-lactamase_625_124,TEM-1,beta-lactamase_625,P62593,0.442889,NO,124,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.181,-3.172,1.991,,,H,A,0.46,-0.9,2.027,,64.34,HHH,-1.152,0.213352,0.00481399,0.442889 beta-lactamase_2500_T131H,beta-lactamase_2500_131,TEM-1,beta-lactamase_2500,P62593,0.443041,NO,131,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.328,-4.721,3.393,,,H,A,0.22,-0.69,3.048,,67.48,PPH,-1.00867,0.361275,0.00345886,0.443041 kka2_1:1_A13M,kka2_1:1_13,Kka2,kka2_1:1,P00552,0.443122,NO,13,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.248,-3.735,1.487,,0.689,G,A,0.46,0.99,25.015,25.015,92.05,OHH,-1.646,0.520039,0.00784241,0.443122 beta-lactamase_156_I93D,beta-lactamase_156_93,TEM-1,beta-lactamase_156,P62593,0.443143,NO,93,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.401,-4.003,2.602,,0.128,E,B,0.48,0.44,1.524,,67.83,BHB,-1.873,0.111618,0.00527066,0.443143 kka2_1:1_A191R,kka2_1:1_191,Kka2,kka2_1:1,P00552,0.443153,NO,191,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.831,-3.8,2.969,,,.,b,0.46,-0.94,0.53,,50,AHO,-0.868667,0.520039,0.00338807,0.443153 kka2_1:2_L259W,kka2_1:2_259,Kka2,kka2_1:2,P00552,0.443154,NO,259,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.088,-5.209,4.121,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.295029,0.0206964,0.443154 kka2_1:8_K50N,kka2_1:8_50,Kka2,kka2_1:8,P00552,0.443165,NO,50,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-0.833,-3.499,2.666,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.100394,0.00138626,0.443165 kka2_1:8_K50N,kka2_1:8_50,Kka2,kka2_1:8,P00552,0.443165,NO,50,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-0.833,-3.499,2.666,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.100394,0.00138626,0.443165 kka2_1:1_V153A,kka2_1:1_153,Kka2,kka2_1:1,P00552,0.443179,NO,153,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.092,-2.452,1.36,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.520039,0.00501119,0.443179 beta-lactamase_625_G281W,beta-lactamase_625_281,TEM-1,beta-lactamase_625,P62593,0.443214,NO,281,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.213352,0.0406482,0.443214 kka2_1:4_L259G,kka2_1:4_259,Kka2,kka2_1:4,P00552,0.443258,NO,259,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.088,-3.711,2.623,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.168804,0.0206964,0.443258 beta-lactamase_39_G249V,beta-lactamase_39_249,TEM-1,beta-lactamase_39,P62593,0.4433,NO,249,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.312,,,,0.256,S,B,0.23,0.04,30.841,30.841,72.73,HOO,-1.81367,0.0495842,0.00220169,0.4433 kka2_1:1_C192D,kka2_1:1_192,Kka2,kka2_1:1,P00552,0.443364,NO,192,C,D,CD,Special,negativeCharge,5.07,5.0516,-0.0184,154,121,133,12,108.5,111.1,2.6,-1.067,-3.871,2.804,,0.095,.,B,0.46,-0.75,2.749,,50,HOH,-0.960333,0.520039,0.00485428,0.443364 beta-lactamase_625_I261W,beta-lactamase_625_261,TEM-1,beta-lactamase_625,P62593,0.443505,NO,261,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.213352,0.0123091,0.443505 kka2_1:2_G30R,kka2_1:2_30,Kka2,kka2_1:2,P00552,0.443519,NO,30,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.596,-3.961,3.365,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.295029,0.00159208,0.443519 hsp90_G584T,hsp90_584,hsp90,hsp90,P02829,0.443536,NO,584,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-2.511,-2.8,0,5.20094,0.414,S,b,0.84,0.33,,,,HOH,-3.32733,0.368192,0.000222939,0.443536 Ubiquitin_G10L,Ubiquitin_10,Uba1,Ubiquitin,P0CG48,0.443548,NO,10,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.396,-3.552,2.156,5.29806,0.115,S,l,,0.2,,,,POB,-1.38633,0.205827,0.000748953,0.443548 Ubiquitin_G76S,Ubiquitin_76,Uba1,Ubiquitin,P0CG48,0.443548,NO,76,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.651,-2.296,0.645,5.7647,0.23,,B,0.12,0.08,9.665,9.665,34.31,OOO,-1.632,0.205827,0.000653872,0.443548 Ubiquitin_K11Y,Ubiquitin_11,Uba1,Ubiquitin,P0CG48,0.443548,NO,11,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.354,-4.058,2.704,5.16813,0.401,,B,2.81,0.84,0.335,,25.84,OBP,-1.346,0.205827,0.000535553,0.443548 Ubiquitin_L50A,Ubiquitin_50,Uba1,Ubiquitin,P0CG48,0.443548,NO,50,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.107,-3.041,1.934,5.19399,0.029,,B,,-0.92,,,,PHA,-1.52733,0.205827,0.000734242,0.443548 Ubiquitin_L8E,Ubiquitin_8,Uba1,Ubiquitin,P0CG48,0.443548,NO,8,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.723,-3.653,1.93,5.28016,0.664,T,A,0.08,-0.34,0.664,,29.05,PHP,-1.51567,0.205827,0.000726165,0.443548 Ubiquitin_R42D,Ubiquitin_42,Uba1,Ubiquitin,P0CG48,0.443548,NO,42,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.571,-3.721,2.15,5.07805,0.244,E,B,0.68,-0.54,1.976,,72.85,PBH,-1.38967,0.205827,0.000622265,0.443548 beta-lactamase_2500_L146Q,beta-lactamase_2500_146,TEM-1,beta-lactamase_2500,P62593,0.443575,NO,146,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.462,-4.29,2.828,,0.007,H,A,0.55,-0.56,1.578,,64.69,AHP,-1.656,0.361275,0.00474542,0.443575 kka2_1:1_D90V,kka2_1:1_90,Kka2,kka2_1:1,P00552,0.44363,NO,90,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.459,-3.794,1.335,,0.104,E,B,0.75,0.73,6.085,,64.39,BAH,-1.72833,0.520039,0.00583842,0.44363 beta-lactamase_2500_L135S,beta-lactamase_2500_135,TEM-1,beta-lactamase_2500,P62593,0.443643,NO,135,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.002,-3.64,2.638,,0.117,H,A,0.55,-0.58,0.795,,43.71,PHH,-1.03767,0.361275,0.00244423,0.443643 kka2_1:8_G99L,kka2_1:8_99,Kka2,kka2_1:8,P00552,0.443702,NO,99,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.596,-3.836,3.24,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.100394,0.00186055,0.443702 kka2_1:8_G99L,kka2_1:8_99,Kka2,kka2_1:8,P00552,0.443702,NO,99,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.596,-3.836,3.24,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.100394,0.00186055,0.443702 beta-lactamase_0_S128V,beta-lactamase_0_128,TEM-1,beta-lactamase_0,P62593,0.443706,NO,128,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-0.84,-3.529,2.689,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.0500837,0.00071483,0.443706 kka2_1:2_L107Y,kka2_1:2_107,Kka2,kka2_1:2,P00552,0.443983,NO,107,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.238,-4.146,2.908,,0.197,,B,1.59,-1.1,2.68,,71.59,BHH,-2.143,0.295029,0.00561937,0.443983 kka2_1:2_E235N,kka2_1:2_235,Kka2,kka2_1:2,P00552,0.444005,NO,235,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.955,-3.12,1.165,,0.631,H,A,1.04,0.12,26.048,26.048,65.53,OAH,-2.07267,0.295029,0.0102806,0.444005 beta-lactamase_W227A,beta-lactamase_227,TEM-1,beta-lactamase,P62593,0.444043,NO,227,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-0.982,-3.46,2.478,4.86393,0.272,,B,0.99,-0.29,1.37,,74.48,OHH,-1.595,0.221079,0.00226019,0.444043 beta-lactamase_L79S,beta-lactamase_79,TEM-1,beta-lactamase,P62593,0.444144,NO,79,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.842,-3.608,2.766,4.98681,0.007,H,A,1.07,-0.16,0.823,,50.35,HHP,-1.44333,0.221079,0.000947397,0.444144 kka2_1:2_D220T,kka2_1:2_220,Kka2,kka2_1:2,P00552,0.444259,NO,220,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.787,-3.448,2.661,,,H,A,0.75,-1.14,0.745,,46.59,PAH,-1.152,0.295029,0.00158066,0.444259 kka2_1:2_V36D,kka2_1:2_36,Kka2,kka2_1:2,P00552,0.444451,NO,36,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-0.898,-3.992,3.094,,0.292,E,B,1.48,0.21,1.064,,52.27,HHH,-1.484,0.295029,0.00245633,0.444451 beta-lactamase_156_I229Q,beta-lactamase_156_229,TEM-1,beta-lactamase_156,P62593,0.444521,NO,229,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.267,-4.304,3.037,,0.083,E,B,0.48,-0.76,1.114,,50,HHH,-1.58767,0.111618,0.00477249,0.444521 kka2_1:4_C131G,kka2_1:4_131,Kka2,kka2_1:4,P00552,0.444527,NO,131,C,G,CG,Special,Special,5.07,3.29388,-1.77612,159,121,75,-46,108.5,60.1,-48.4,-0.831,-3.611,2.78,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.168804,0.00170814,0.444527 Pab1_F129L,Pab1_129,Pab1,Pab1,P04147,0.444569,NO,129,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.269,-2.829,1.56,,0.219,E,B,0.03,-0.07,1.307,,73.83,HHH,-1.27533,0.175299,0.000625182,0.444569 beta-lactamase_L74S,beta-lactamase_74,TEM-1,beta-lactamase,P62593,0.444576,NO,74,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.296,-3.399,2.103,5.50288,,H,A,1.75,-0.91,1.581,,50,HHO,-1.34933,0.221079,0.00493255,0.444576 kka2_1:2_M120K,kka2_1:2_120,Kka2,kka2_1:2,P00552,0.444602,NO,120,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-3.877,-3.733,-0.144,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.295029,0.00265808,0.444602 kka2_1:2_F133R,kka2_1:2_133,Kka2,kka2_1:2,P00552,0.444669,NO,133,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-0.871,-4.184,3.313,,0.178,.,B,0.58,0.43,1.999,,42.42,OHA,-0.871667,0.295029,0.00182168,0.444669 beta-lactamase_2500_D99W,beta-lactamase_2500_99,TEM-1,beta-lactamase_2500,P62593,0.444693,NO,99,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.191,-5.462,4.271,,0.402,G,A,0.75,0.36,1.318,,64.69,PAH,-1.794,0.361275,0.00305446,0.444693 kka2_1:1_S114T,kka2_1:1_114,Kka2,kka2_1:1,P00552,0.444694,NO,114,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.527,-2.564,0.037,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.520039,0.00705262,0.444694 beta-lactamase_2500_D212F,beta-lactamase_2500_212,TEM-1,beta-lactamase_2500,P62593,0.444835,NO,212,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.624,-4.334,2.71,,0.037,,b,0.75,-0.58,12.482,,74.48,HAB,-1.77667,0.361275,0.00644302,0.444835 beta-lactamase_K213D,beta-lactamase_213,TEM-1,beta-lactamase,P62593,0.444877,NO,213,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.81,-3.577,1.767,5.63167,0.67,,A,1.59,0.29,3.924,,67.83,ABH,-1.57767,0.221079,0.00610411,0.444877 kka2_1:2_C77F,kka2_1:2_77,Kka2,kka2_1:2,P00552,0.444894,NO,77,C,F,CF,Special,Hydrophobic,5.07,3.32051,-1.74949,205,121,165,44,108.5,189.9,81.4,-1.477,-4.235,2.758,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.295029,0.00441216,0.444894 beta-lactamase_625_G249S,beta-lactamase_625_249,TEM-1,beta-lactamase_625,P62593,0.444903,NO,249,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.213352,0.00220169,0.444903 kka2_1:1_D90Q,kka2_1:1_90,Kka2,kka2_1:1,P00552,0.44492,NO,90,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.459,-2.781,0.322,,0.104,E,B,0.75,0.73,6.085,,64.39,BAH,-1.72833,0.520039,0.00583842,0.44492 beta-lactamase_156_M67Y,beta-lactamase_156_67,TEM-1,beta-lactamase_156,P62593,0.444945,NO,67,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-2.231,-4.282,2.051,,0.006,G,P,0.55,-0.81,1.463,,65.03,HHP,-1.502,0.111618,0.00409753,0.444945 kka2_1:2_M120V,kka2_1:2_120,Kka2,kka2_1:2,P00552,0.444988,NO,120,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-3.877,-2.338,-1.539,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.295029,0.00265808,0.444988 beta-lactamase_2500_R59S,beta-lactamase_2500_59,TEM-1,beta-lactamase_2500,P62593,0.444997,NO,59,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.345,-2.706,1.361,,0.329,S,L,1.2,-0.09,3.719,,73.08,HBO,-2.24267,0.361275,0.00318082,0.444997 beta-lactamase_D161R,beta-lactamase_161,TEM-1,beta-lactamase,P62593,0.445022,NO,161,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.891,-3.902,3.011,5.12208,0.341,,A,0.23,-0.52,1.602,,61.19,HAB,-0.961333,0.221079,0.000897697,0.445022 beta-lactamase_2500_L100A,beta-lactamase_2500_100,TEM-1,beta-lactamase_2500,P62593,0.445132,NO,100,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.218,-3.158,1.94,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.361275,0.00413885,0.445132 beta-lactamase_2500_S201F,beta-lactamase_2500_201,TEM-1,beta-lactamase_2500,P62593,0.445185,NO,201,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.183,-4.138,2.955,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.361275,0.00198815,0.445185 beta-lactamase_2500_I93H,beta-lactamase_2500_93,TEM-1,beta-lactamase_2500,P62593,0.445197,NO,93,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.401,-5.004,3.603,,0.128,E,B,0.48,0.44,19.374,19.374,67.83,BHB,-1.873,0.361275,0.00527066,0.445197 beta-lactamase_2500_P60C,beta-lactamase_2500_60,TEM-1,beta-lactamase_2500,P62593,0.445261,NO,60,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-2.469,-4.889,2.42,,0.256,T,A,0.52,-0.56,1.581,,77.62,BOA,-1.97633,0.361275,0.00521318,0.445261 kka2_1:2_D220H,kka2_1:2_220,Kka2,kka2_1:2,P00552,0.445287,NO,220,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.787,-4.544,3.757,,,H,A,0.75,-1.14,0.745,,46.59,PAH,-1.152,0.295029,0.00158066,0.445287 kka2_1:2_F203T,kka2_1:2_203,Kka2,kka2_1:2,P00552,0.445287,NO,203,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-0.911,-3.673,2.762,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.295029,0.00318738,0.445287 kka2_1:4_L107K,kka2_1:4_107,Kka2,kka2_1:4,P00552,0.4453,NO,107,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.238,-3.819,2.581,,0.197,.,B,0.55,-1.1,0.398,,71.59,BHH,-2.143,0.168804,0.00561937,0.4453 beta-lactamase_625_D48Y,beta-lactamase_625_48,TEM-1,beta-lactamase_625,P62593,0.445321,NO,48,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.101,-4.182,3.081,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.213352,0.0027273,0.445321 kka2_1:1_E86Q,kka2_1:1_86,Kka2,kka2_1:1,P00552,0.445333,NO,86,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.86,-2.883,1.023,,0.369,.,B,1.04,1.92,18.506,18.506,63.26,PAH,-1.98067,0.520039,0.00642858,0.445333 kka2_1:1_E96F,kka2_1:1_96,Kka2,kka2_1:1,P00552,0.445357,NO,96,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.573,-4.257,1.684,,0.476,,B,1.52,-0.65,1.254,,71.59,OAH,-2.143,0.520039,0.00369441,0.445357 beta-lactamase_156_M115P,beta-lactamase_156_115,TEM-1,beta-lactamase_156,P62593,0.445359,NO,115,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.389,-4.034,2.645,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.111618,0.0034337,0.445359 kka2_1:4_H135W,kka2_1:4_135,Kka2,kka2_1:4,P00552,0.445395,NO,135,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-1.331,-5.284,3.953,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.168804,0.00532566,0.445395 kka2_1:8_G213L,kka2_1:8_213,Kka2,kka2_1:8,P00552,0.445397,NO,213,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.596,-3.836,3.24,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.100394,0.00187654,0.445397 kka2_1:8_G213L,kka2_1:8_213,Kka2,kka2_1:8,P00552,0.445397,NO,213,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.596,-3.836,3.24,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.100394,0.00187654,0.445397 kka2_1:2_D134T,kka2_1:2_134,Kka2,kka2_1:2,P00552,0.4454,NO,134,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.969,-3.471,2.502,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.295029,0.00270812,0.4454 kka2_1:1_H8A,kka2_1:1_8,Kka2,kka2_1:1,P00552,0.445458,NO,8,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-2.759,-1.998,-0.761,,,,,,,16.971,16.971,71.59,HBH,-2.25467,0.520039,0.00256422,0.445458 kka2_1:1_P98N,kka2_1:1_98,Kka2,kka2_1:1,P00552,0.445516,NO,98,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.526,-3.852,2.326,,0.391,S,B,0.52,-0.65,1.521,,63.26,HOO,-1.19167,0.520039,0.00622754,0.445516 beta-lactamase_156_D155Q,beta-lactamase_156_155,TEM-1,beta-lactamase_156,P62593,0.445563,NO,155,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.889,-3.667,2.778,,0.049,,B,0.75,-0.9,0.315,,64.69,OAB,-1.62267,0.111618,0.00135315,0.445563 beta-lactamase_625_I285N,beta-lactamase_625_285,TEM-1,beta-lactamase_625,P62593,0.445638,NO,285,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.213352,0.101555,0.445638 kka2_1:1_A14H,kka2_1:1_14,Kka2,kka2_1:1,P00552,0.445647,NO,14,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.837,-4.803,2.966,,0.728,G,A,0.46,0.7,1.17,,71.59,HHH,-1.82567,0.520039,0.00706614,0.445647 beta-lactamase_625_T187E,beta-lactamase_625_187,TEM-1,beta-lactamase_625,P62593,0.445653,NO,187,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.401,-3.52,2.119,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.213352,0.00491782,0.445653 kka2_1:2_G201K,kka2_1:2_201,Kka2,kka2_1:2,P00552,0.445678,NO,201,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.56,-2.796,1.236,,0.149,T,l,0.29,-0.57,16.092,16.092,52.65,POB,-1.92233,0.295029,0.00820117,0.445678 kka2_1:1_Q163G,kka2_1:1_163,Kka2,kka2_1:1,P00552,0.445679,NO,163,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.162,-3.698,1.536,,0.58,T,B,0.64,1.85,2.779,,64.02,BPO,-1.78333,0.520039,0.00719507,0.445679 beta-lactamase_G239Q,beta-lactamase_239,TEM-1,beta-lactamase,P62593,0.445728,NO,239,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.819,-4.068,3.249,4.85529,0.115,T,l,0.77,-0.62,1.817,,42.31,BOP,-1.45267,0.221079,0.00213852,0.445728 beta-lactamase_156_V72E,beta-lactamase_156_72,TEM-1,beta-lactamase_156,P62593,0.445739,NO,72,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.658,-3.755,2.097,,,H,A,0.44,-1.03,1.92,,65.73,BHH,-1.32167,0.111618,0.00501194,0.445739 kka2_1:1_Y244W,kka2_1:1_244,Kka2,kka2_1:1,P00552,0.445831,NO,244,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-0.775,-4.226,3.451,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.520039,0.00453187,0.445831 kka2_1:1_S68F,kka2_1:1_68,Kka2,kka2_1:1,P00552,0.44597,NO,68,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.623,-4.425,1.802,,0.48,H,A,0.27,-0.1,2.655,,71.59,HPH,-1.40767,0.520039,0.00608265,0.44597 kka2_1:1_A71N,kka2_1:1_71,Kka2,kka2_1:1,P00552,0.445982,NO,71,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.824,-2.731,0.907,,0.553,H,A,0.46,0.08,9.788,,64.39,HHP,-1.74033,0.520039,0.00727707,0.445982 beta-lactamase_625_G141P,beta-lactamase_625_141,TEM-1,beta-lactamase_625,P62593,0.446091,NO,141,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.828,-3.881,3.053,,0.575,T,l,0.29,-0.28,0.198,,64.69,HOO,-1.08933,0.213352,0.0012419,0.446091 kka2_1:8_V185M,kka2_1:8_185,Kka2,kka2_1:8,P00552,0.446108,NO,185,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.045,-3.067,2.022,,0.058,E,B,1.48,-0.49,1.234,,46.97,HHH,-1.184,0.100394,0.00367031,0.446108 kka2_1:8_V185M,kka2_1:8_185,Kka2,kka2_1:8,P00552,0.446108,NO,185,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.045,-3.067,2.022,,0.058,E,B,1.48,-0.49,1.234,,46.97,HHH,-1.184,0.100394,0.00367031,0.446108 kka2_1:2_L259P,kka2_1:2_259,Kka2,kka2_1:2,P00552,0.446135,NO,259,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.088,-4.066,2.978,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.295029,0.0206964,0.446135 gb1_F278V,gb1_278,gb1,gb1,P06654,0.446141,NO,278,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.418,-3.203,1.785,,,,,,,3.233,,35.71,PHP,-1.503,0.177985,0.00295699,0.446141 gb1_K230P,gb1_230,gb1,gb1,P06654,0.446141,NO,230,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.701,-3.666,1.965,,,,,,,0.166,,11.83,HBH,-1.52867,0.177985,0.00331703,0.446141 gb1_N261I,gb1_261,gb1,gb1,P06654,0.446141,NO,261,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-1.863,-3.657,1.794,,,,,,,1.191,,44.87,HPA,-2.16033,0.177985,0.0061875,0.446141 kka2_1:2_T130W,kka2_1:2_130,Kka2,kka2_1:2,P00552,0.446149,NO,130,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.392,-5.541,3.149,,0.561,G,A,0.22,0.77,0.5,,92.05,HPO,-1.62633,0.295029,0.00804204,0.446149 kka2_1:4_T225N,kka2_1:4_225,Kka2,kka2_1:4,P00552,0.446163,NO,225,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.393,-4.009,1.616,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.168804,0.0113598,0.446163 kka2_1:1_F256A,kka2_1:1_256,Kka2,kka2_1:1,P00552,0.446199,NO,256,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.49,-3.439,1.949,,,H,A,1.62,-0.78,2.354,,53.03,HHH,-1.423,0.520039,0.0132841,0.446199 beta-lactamase_2500_L205F,beta-lactamase_2500_205,TEM-1,beta-lactamase_2500,P62593,0.44625,NO,205,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.922,-2.306,1.384,,,H,A,0.55,-0.46,0.831,,42.31,PHH,-1.57767,0.361275,0.00255802,0.44625 kka2_1:1_G88L,kka2_1:1_88,Kka2,kka2_1:1,P00552,0.446355,NO,88,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.689,-3.754,2.065,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.520039,0.00685559,0.446355 kka2_1:8_D190H,kka2_1:8_190,Kka2,kka2_1:8,P00552,0.446374,NO,190,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.708,-4.483,3.775,,0.213,S,b,0.29,-0.82,,,,OAH,-0.711667,0.100394,0.00247989,0.446374 kka2_1:8_D190H,kka2_1:8_190,Kka2,kka2_1:8,P00552,0.446374,NO,190,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.708,-4.483,3.775,,0.213,S,b,0.29,-0.82,,,,OAH,-0.711667,0.100394,0.00247989,0.446374 kka2_1:2_L47T,kka2_1:2_47,Kka2,kka2_1:2,P00552,0.44642,NO,47,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.265,-3.56,2.295,,0.139,E,B,0.55,-0.86,2.369,,63.26,HHH,-1.77933,0.295029,0.00509386,0.44642 beta-lactamase_2500_A215K,beta-lactamase_2500_215,TEM-1,beta-lactamase_2500,P62593,0.446444,NO,215,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.503,-3.575,2.072,,,,a,0.46,-0.93,3.516,,74.48,HHO,-1.42633,0.361275,0.00544007,0.446444 beta-lactamase_625_A123P,beta-lactamase_625_123,TEM-1,beta-lactamase_625,P62593,0.446444,NO,123,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.834,-3.704,2.87,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.213352,0.0010157,0.446444 kka2_1:8_L107S,kka2_1:8_107,Kka2,kka2_1:8,P00552,0.446488,NO,107,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.238,-3.641,2.403,,0.197,.,B,0.55,-1.1,4.478,,71.59,BHH,-2.143,0.100394,0.00561937,0.446488 kka2_1:8_L107S,kka2_1:8_107,Kka2,kka2_1:8,P00552,0.446488,NO,107,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.238,-3.641,2.403,,0.197,.,B,0.55,-1.1,4.478,,71.59,BHH,-2.143,0.100394,0.00561937,0.446488 beta-lactamase_156_A123P,beta-lactamase_156_123,TEM-1,beta-lactamase_156,P62593,0.446496,NO,123,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.834,-3.704,2.87,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.111618,0.0010157,0.446496 beta-lactamase_2500_D161Q,beta-lactamase_2500_161,TEM-1,beta-lactamase_2500,P62593,0.446512,NO,161,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.891,-3.667,2.776,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.361275,0.000897697,0.446512 kka2_1:1_D82V,kka2_1:1_82,Kka2,kka2_1:1,P00552,0.446516,NO,82,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.946,-3.073,1.127,,0.341,E,b,0.75,0.52,11.345,11.345,63.64,HAH,-1.98,0.520039,0.00637516,0.446516 beta-lactamase_625_G114L,beta-lactamase_625_114,TEM-1,beta-lactamase_625,P62593,0.446551,NO,114,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.094,-3.637,2.543,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.213352,0.00224919,0.446551 kka2_1:1_L107V,kka2_1:1_107,Kka2,kka2_1:1,P00552,0.446576,NO,107,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.238,-2.216,0.978,,0.197,.,B,0.55,-1.1,3.542,,71.59,BHH,-2.143,0.520039,0.00561937,0.446576 beta-lactamase_625_L146G,beta-lactamase_625_146,TEM-1,beta-lactamase_625,P62593,0.446581,NO,146,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.462,-3.742,2.28,,0.007,H,A,0.55,-0.56,2.16,,64.69,AHP,-1.656,0.213352,0.00474542,0.446581 beta-lactamase_2500_S266V,beta-lactamase_2500_266,TEM-1,beta-lactamase_2500,P62593,0.446697,NO,266,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.361275,0.0140785,0.446697 beta-lactamase_2500_V101F,beta-lactamase_2500_101,TEM-1,beta-lactamase_2500,P62593,0.446785,NO,101,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.295,-3.936,2.641,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.361275,0.00374492,0.446785 kka2_1:2_P132M,kka2_1:2_132,Kka2,kka2_1:2,P00552,0.446809,NO,132,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.775,-4.731,3.956,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.295029,0.0018489,0.446809 kka2_1:8_S32F,kka2_1:8_32,Kka2,kka2_1:8,P00552,0.446818,NO,32,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-0.804,-4.095,3.291,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.100394,0.00149998,0.446818 kka2_1:8_S32F,kka2_1:8_32,Kka2,kka2_1:8,P00552,0.446818,NO,32,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-0.804,-4.095,3.291,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.100394,0.00149998,0.446818 beta-lactamase_2500_C75L,beta-lactamase_2500_75,TEM-1,beta-lactamase_2500,P62593,0.446819,NO,75,C,L,CL,Special,Hydrophobic,5.07,9.7088,4.6388,198,121,131,10,108.5,166.7,58.2,-1.245,-3.28,2.035,,,H,A,0.46,-0.87,0.844,,50,HOO,-1.24333,0.361275,0.0034616,0.446819 kka2_1:1_W15K,kka2_1:1_15,Kka2,kka2_1:1,P00552,0.446854,NO,15,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-1.392,-3.944,2.552,,0.01,G,A,0.47,0.15,20.149,20.149,52.27,HHH,-2.10533,0.520039,0.00585505,0.446854 kka2_1:4_D157R,kka2_1:4_157,Kka2,kka2_1:4,P00552,0.446905,NO,157,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.993,-3.936,2.943,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.168804,0.0042313,0.446905 beta-lactamase_156_W288S,beta-lactamase_156_288,TEM-1,beta-lactamase_156,P62593,0.446931,NO,288,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,,,,,,,,,,,,,BHO,,0.111618,,0.446931 Pab1_Y143P,Pab1_143,Pab1,Pab1,P04147,0.446933,NO,143,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-1.961,-3.938,1.977,,0.409,H,A,,0.3,,,,HHA,-1.39633,0.175299,0.00160364,0.446933 kka2_1:2_N195L,kka2_1:2_195,Kka2,kka2_1:2,P00552,0.446988,NO,195,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-0.836,-3.655,2.819,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.295029,0.00276134,0.446988 kka2_1:4_L47S,kka2_1:4_47,Kka2,kka2_1:4,P00552,0.447045,NO,47,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.265,-3.626,2.361,,0.139,E,B,0.55,-0.86,2.369,,63.26,HHH,-1.77933,0.168804,0.00509386,0.447045 kka2_1:2_D118P,kka2_1:2_118,Kka2,kka2_1:2,P00552,0.44705,NO,118,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.07,-4.037,1.967,,0.61,H,A,0.75,-0.05,2.237,,64.39,HAH,-1.32367,0.295029,0.0067852,0.44705 beta-lactamase_625_L219R,beta-lactamase_625_219,TEM-1,beta-lactamase_625,P62593,0.447054,NO,219,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.313,-4.126,2.813,,,I,A,0.55,-0.51,5.627,,74.48,HHB,-1.21533,0.213352,0.00664345,0.447054 kka2_1:4_A255I,kka2_1:4_255,Kka2,kka2_1:4,P00552,0.447097,NO,255,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.715,-4.011,2.296,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.168804,0.0126809,0.447097 beta-lactamase_2500_L79F,beta-lactamase_2500_79,TEM-1,beta-lactamase_2500,P62593,0.447151,NO,79,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.842,-3.643,2.801,,0.007,H,A,0.55,-0.16,0.823,,50.35,HHP,-1.44333,0.361275,0.000947397,0.447151 kka2_1:1_C77L,kka2_1:1_77,Kka2,kka2_1:1,P00552,0.447214,NO,77,C,L,CL,Special,Hydrophobic,5.07,9.7088,4.6388,198,121,131,10,108.5,166.7,58.2,-1.477,-3.33,1.853,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.520039,0.00441216,0.447214 beta-lactamase_2500_T131F,beta-lactamase_2500_131,TEM-1,beta-lactamase_2500,P62593,0.447345,NO,131,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.328,-4.204,2.876,,,H,A,0.22,-0.69,3.048,,67.48,PPH,-1.00867,0.361275,0.00345886,0.447345 WW_domain_R203G,WW_domain_203,Yap65,WW_domain,P46937,0.447374,NO,203,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.539,-3.247,1.708,5.41321,,,,,,1.9,,70.04,OBO,-1.4695,0.153962,0.00172433,0.447374 kka2_1:4_L126A,kka2_1:4_126,Kka2,kka2_1:4,P00552,0.447381,NO,126,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.246,-3.18,1.934,,0.285,S,B,0.55,0.12,0.302,,51.89,PHA,-1.744,0.168804,0.0066485,0.447381 kka2_1:8_C192E,kka2_1:8_192,Kka2,kka2_1:8,P00552,0.447437,NO,192,C,E,CE,Special,negativeCharge,5.07,3.22,-1.85,170,121,147,26,108.5,138.4,29.9,-1.067,-3.955,2.888,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.100394,0.00485428,0.447437 kka2_1:8_C192E,kka2_1:8_192,Kka2,kka2_1:8,P00552,0.447437,NO,192,C,E,CE,Special,negativeCharge,5.07,3.22,-1.85,170,121,147,26,108.5,138.4,29.9,-1.067,-3.955,2.888,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.100394,0.00485428,0.447437 kka2_1:8_H135W,kka2_1:8_135,Kka2,kka2_1:8,P00552,0.447452,NO,135,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-1.331,-5.284,3.953,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.100394,0.00532566,0.447452 kka2_1:8_H135W,kka2_1:8_135,Kka2,kka2_1:8,P00552,0.447452,NO,135,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-1.331,-5.284,3.953,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.100394,0.00532566,0.447452 beta-lactamase_S128G,beta-lactamase_128,TEM-1,beta-lactamase,P62593,0.447463,NO,128,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-0.84,-2.908,2.068,5.37153,0.08,,L,0.73,-0.32,,,,HPA,-1.30233,0.221079,0.00071483,0.447463 beta-lactamase_I229S,beta-lactamase_229,TEM-1,beta-lactamase,P62593,0.447489,NO,229,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.267,-3.615,2.348,5.0911,0.083,E,B,1,-0.76,1.114,,50,HHH,-1.58767,0.221079,0.00477249,0.447489 Pab1_H172F,Pab1_172,Pab1,Pab1,P04147,0.447631,NO,172,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-1.21,-3.659,2.449,,0.076,E,B,0.35,-0.87,,,,HBH,-1.26667,0.175299,0.000296642,0.447631 kka2_1:4_L92W,kka2_1:4_92,Kka2,kka2_1:4,P00552,0.447679,NO,92,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.893,-5.185,4.292,,0.007,E,B,0.55,-0.19,1.447,,63.26,HHH,-0.962,0.168804,0.00307177,0.447679 beta-lactamase_156_L79H,beta-lactamase_156_79,TEM-1,beta-lactamase_156,P62593,0.447844,NO,79,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.842,-4.903,4.061,,0.007,H,A,0.55,-0.16,1.831,,50.35,HHP,-1.44333,0.111618,0.000947397,0.447844 beta-lactamase_2500_F70L,beta-lactamase_2500_70,TEM-1,beta-lactamase_2500,P62593,0.447864,NO,70,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.169,-2.96,1.791,,,H,A,0.58,-1.34,1.918,,63.99,PHB,-0.980667,0.361275,0.00193499,0.447864 beta-lactamase_E87K,beta-lactamase_87,TEM-1,beta-lactamase,P62593,0.447906,NO,87,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.421,-2.715,1.294,5.41929,0.048,,B,0.52,0.92,1.754,,64.69,PAP,-1.969,0.221079,0.00337888,0.447906 beta-lactamase_2500_A235Q,beta-lactamase_2500_235,TEM-1,beta-lactamase_2500,P62593,0.447919,NO,235,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.266,-4.018,2.752,,0.32,E,B,0.46,-0.86,0.891,,50,OHO,-0.89,0.361275,0.00493474,0.447919 kka2_1:2_K138E,kka2_1:2_138,Kka2,kka2_1:2,P00552,0.447929,NO,138,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-2.5,-1.783,-0.717,,0.594,H,A,2.34,0.98,21.038,21.038,71.59,HBB,-2.48833,0.295029,0.00628542,0.447929 kka2_1:2_D90P,kka2_1:2_90,Kka2,kka2_1:2,P00552,0.447932,NO,90,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.459,-4.102,1.643,,0.104,E,B,0.75,0.73,6.085,,64.39,BAH,-1.72833,0.295029,0.00583842,0.447932 beta-lactamase_2500_D83G,beta-lactamase_2500_83,TEM-1,beta-lactamase_2500,P62593,0.44802,NO,83,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.066,-2.429,1.363,,0.354,H,A,0.75,0.22,0.239,,48.95,HAH,-1.34733,0.361275,0.00205968,0.44802 beta-lactamase_0_D161M,beta-lactamase_0_161,TEM-1,beta-lactamase_0,P62593,0.448046,NO,161,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.891,-4.899,4.008,,0.341,,A,0.75,-0.52,0.795,,61.19,HAB,-0.961333,0.0500837,0.000897697,0.448046 beta-lactamase_D161W,beta-lactamase_161,TEM-1,beta-lactamase,P62593,0.448055,NO,161,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.891,-5.546,4.655,5.12208,0.341,,A,0.23,-0.52,1.602,,61.19,HAB,-0.961333,0.221079,0.000897697,0.448055 kka2_1:8_F203Q,kka2_1:8_203,Kka2,kka2_1:8,P00552,0.448159,NO,203,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-0.911,-4.376,3.465,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.100394,0.00318738,0.448159 kka2_1:8_F203Q,kka2_1:8_203,Kka2,kka2_1:8,P00552,0.448159,NO,203,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-0.911,-4.376,3.465,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.100394,0.00318738,0.448159 kka2_1:8_G210I,kka2_1:8_210,Kka2,kka2_1:8,P00552,0.448232,NO,210,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.095,-4.061,2.966,,0.103,T,A,0.75,-0.62,2.687,,50,OOB,-0.966667,0.100394,0.00598378,0.448232 kka2_1:8_G210I,kka2_1:8_210,Kka2,kka2_1:8,P00552,0.448232,NO,210,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.095,-4.061,2.966,,0.103,T,A,0.75,-0.62,2.687,,50,OOB,-0.966667,0.100394,0.00598378,0.448232 kka2_1:8_V186E,kka2_1:8_186,Kka2,kka2_1:8,P00552,0.448232,NO,186,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.011,-3.841,2.83,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.100394,0.00409703,0.448232 kka2_1:8_V186E,kka2_1:8_186,Kka2,kka2_1:8,P00552,0.448232,NO,186,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.011,-3.841,2.83,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.100394,0.00409703,0.448232 kka2_1:1_D183P,kka2_1:1_183,Kka2,kka2_1:1,P00552,0.448265,NO,183,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.204,-3.861,2.657,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.520039,0.00426304,0.448265 beta-lactamase_L218Y,beta-lactamase_218,TEM-1,beta-lactamase,P62593,0.448376,NO,218,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.391,-4.087,2.696,4.88972,,I,b,2.89,-0.53,12.788,12.788,74.48,OHH,-1.58867,0.221079,0.00618274,0.448376 kka2_1:8_E63V,kka2_1:8_63,Kka2,kka2_1:8,P00552,0.448408,NO,63,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-0.762,-3.557,2.795,,0.043,H,A,1.52,-0.43,,,,AAH,-1.283,0.100394,0.00118399,0.448408 kka2_1:8_E63V,kka2_1:8_63,Kka2,kka2_1:8,P00552,0.448408,NO,63,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-0.762,-3.557,2.795,,0.043,H,A,1.52,-0.43,,,,AAH,-1.283,0.100394,0.00118399,0.448408 kka2_1:2_A224P,kka2_1:2_224,Kka2,kka2_1:2,P00552,0.448557,NO,224,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.977,-3.784,2.807,,,H,A,0.46,-1.26,1.646,,63.64,HHP,-1.41033,0.295029,0.00352047,0.448557 kka2_1:1_V84H,kka2_1:1_84,Kka2,kka2_1:1,P00552,0.448594,NO,84,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-2.279,-3.484,1.205,,0.258,E,B,0.44,1.03,3.484,,71.59,HHP,-2.337,0.520039,0.00724019,0.448594 kka2_1:1_C131G,kka2_1:1_131,Kka2,kka2_1:1,P00552,0.448604,NO,131,C,G,CG,Special,Special,5.07,3.29388,-1.77612,159,121,75,-46,108.5,60.1,-48.4,-0.831,-3.611,2.78,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.520039,0.00170814,0.448604 kka2_1:1_A166D,kka2_1:1_166,Kka2,kka2_1:1,P00552,0.448705,NO,166,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.407,-2.968,0.561,,0.534,.,B,0.46,1.03,1.147,,71.59,HHO,-2.421,0.520039,0.00799912,0.448705 kka2_1:1_V113R,kka2_1:1_113,Kka2,kka2_1:1,P00552,0.448786,NO,113,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.233,-4.233,3,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.520039,0.00650191,0.448786 beta-lactamase_625_L120H,beta-lactamase_625_120,TEM-1,beta-lactamase_625,P62593,0.448827,NO,120,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.044,-3.066,2.022,,,H,A,0.55,-1.13,7.813,,64.69,AHO,-1.13633,0.213352,0.00143563,0.448827 beta-lactamase_2500_S241D,beta-lactamase_2500_241,TEM-1,beta-lactamase_2500,P62593,0.448829,NO,241,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.361275,0.00452736,0.448829 beta-lactamase_2500_S233P,beta-lactamase_2500_233,TEM-1,beta-lactamase_2500,P62593,0.448853,NO,233,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.886,-2.778,0.892,,0.016,E,B,0.27,-1.01,2.851,,77.62,BPO,-1.17267,0.361275,0.00311415,0.448853 kka2_1:1_L165Y,kka2_1:1_165,Kka2,kka2_1:1,P00552,0.448895,NO,165,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-2.453,-4.292,1.839,,0.299,,B,1.59,1.12,2.47,,64.39,OHH,-1.90967,0.520039,0.00801161,0.448895 kka2_1:2_K138I,kka2_1:2_138,Kka2,kka2_1:2,P00552,0.448904,NO,138,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-2.5,-3.288,0.788,,0.594,H,A,2.34,0.98,21.038,21.038,71.59,HBB,-2.48833,0.295029,0.00628542,0.448904 beta-lactamase_39_K232S,beta-lactamase_39_232,TEM-1,beta-lactamase_39,P62593,0.448939,NO,232,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.012,-3.258,2.246,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.0495842,0.00313441,0.448939 PSD95pdz3_A347K,PSD95pdz3_347,PSD95pdz3,PSD95pdz3,P31016,0.448997,NO,347,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.307,-3.139,1.832,4.89689,,,,,15.176,,,,OHA,-1.269,0.0758425,0.00074525,0.448997 PSD95pdz3_N326E,PSD95pdz3_326,PSD95pdz3,PSD95pdz3,P31016,0.449003,NO,326,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-1.41,-2.897,1.487,5.52537,,,,,19.0688,,,,HPH,-1.52133,0.0758425,0.00101078,0.449003 kka2_1:4_P109M,kka2_1:4_109,Kka2,kka2_1:4,P00552,0.449102,NO,109,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.412,-4.773,3.361,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.168804,0.0070929,0.449102 kka2_1:8_C131Y,kka2_1:8_131,Kka2,kka2_1:8,P00552,0.449113,NO,131,C,Y,CY,Special,Hydrophobic,5.07,5.66,0.59,194,121,181,60,108.5,193.6,85.1,-0.831,-4.191,3.36,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.100394,0.00170814,0.449113 kka2_1:8_C131Y,kka2_1:8_131,Kka2,kka2_1:8,P00552,0.449113,NO,131,C,Y,CY,Special,Hydrophobic,5.07,5.66,0.59,194,121,181,60,108.5,193.6,85.1,-0.831,-4.191,3.36,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.100394,0.00170814,0.449113 beta-lactamase_2500_A34G,beta-lactamase_2500_34,TEM-1,beta-lactamase_2500,P62593,0.44914,NO,34,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.059,-3.469,1.41,,,H,A,0.46,-0.54,2.921,,73.78,AHA,-1.74967,0.361275,0.00407913,0.44914 beta-lactamase_625_T69V,beta-lactamase_625_69,TEM-1,beta-lactamase_625,P62593,0.449207,NO,69,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-0.973,-3.175,2.202,,,G,A,0.22,-1.24,2.716,,93.01,PPH,-1.01833,0.213352,0.00127498,0.449207 kka2_1:1_T85R,kka2_1:1_85,Kka2,kka2_1:1,P00552,0.449227,NO,85,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.165,-2.814,0.649,,0.576,E,B,0.82,1.39,16.653,16.653,71.59,HPA,-2.10133,0.520039,0.00634493,0.449227 beta-lactamase_39_V31E,beta-lactamase_39_31,TEM-1,beta-lactamase_39,P62593,0.449342,NO,31,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.822,-3.908,2.086,,,H,A,0.44,-0.46,2.885,,73.78,BHB,-2.03767,0.0495842,0.00478065,0.449342 Pab1_I196D,Pab1_196,Pab1,Pab1,P04147,0.449424,NO,196,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.795,-3.811,2.016,,,,,,,2.013,,80.59,AHH,-1.44667,0.175299,0.0016933,0.449424 kka2_1:1_V198Q,kka2_1:1_198,Kka2,kka2_1:1,P00552,0.449446,NO,198,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.719,-4.058,2.339,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.520039,0.00835002,0.449446 kka2_1:1_R122T,kka2_1:1_122,Kka2,kka2_1:1,P00552,0.449449,NO,122,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.175,-2.452,0.277,,0.487,H,A,1.2,0.26,1.356,,71.59,BBH,-1.53833,0.520039,0.00736512,0.449449 PSD95pdz3_V362W,PSD95pdz3_362,PSD95pdz3,PSD95pdz3,P31016,0.449464,NO,362,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.465,-5.004,3.539,4.99436,,,,,19.6443,,,,PHP,-1.46467,0.0758425,0.000538527,0.449464 kka2_1:1_H139K,kka2_1:1_139,Kka2,kka2_1:1,P00552,0.449517,NO,139,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-2.809,-2.699,-0.11,,0.471,H,A,0.17,0.68,1.153,,63.64,BBB,-2.22,0.520039,0.00734779,0.449517 kka2_1:1_A14K,kka2_1:1_14,Kka2,kka2_1:1,P00552,0.449527,NO,14,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.837,-2.596,0.759,,0.728,G,A,0.46,0.7,1.17,,71.59,HHH,-1.82567,0.520039,0.00706614,0.449527 kka2_1:8_E169P,kka2_1:8_169,Kka2,kka2_1:8,P00552,0.449552,NO,169,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.996,-4.008,2.012,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.100394,0.00730086,0.449552 kka2_1:8_E169P,kka2_1:8_169,Kka2,kka2_1:8,P00552,0.449552,NO,169,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.996,-4.008,2.012,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.100394,0.00730086,0.449552 kka2_1:8_P128E,kka2_1:8_128,Kka2,kka2_1:8,P00552,0.449552,NO,128,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.922,-3.892,1.97,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.100394,0.00774689,0.449552 kka2_1:8_P128E,kka2_1:8_128,Kka2,kka2_1:8,P00552,0.449552,NO,128,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.922,-3.892,1.97,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.100394,0.00774689,0.449552 beta-lactamase_2500_V117F,beta-lactamase_2500_117,TEM-1,beta-lactamase_2500,P62593,0.449658,NO,117,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.53,-3.756,2.226,,,H,A,0.44,-0.34,1.23,,65.03,PHB,-1.741,0.361275,0.00467906,0.449658 Pab1_L133S,Pab1_133,Pab1,Pab1,P04147,0.44976,NO,133,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.039,-3.428,2.389,,0.015,,B,1.75,1.03,,,,PHB,-1.22,0.175299,0.000345939,0.44976 beta-lactamase_625_I245S,beta-lactamase_625_245,TEM-1,beta-lactamase_625,P62593,0.449775,NO,245,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.213352,0.00391032,0.449775 kka2_1:1_A13I,kka2_1:1_13,Kka2,kka2_1:1,P00552,0.44984,NO,13,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.248,-3.155,0.907,,0.689,G,A,0.46,0.99,25.015,25.015,92.05,OHH,-1.646,0.520039,0.00784241,0.44984 kka2_1:4_C209F,kka2_1:4_209,Kka2,kka2_1:4,P00552,0.449882,NO,209,C,F,CF,Special,Hydrophobic,5.07,3.32051,-1.74949,205,121,165,44,108.5,189.9,81.4,-0.906,-4.063,3.157,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.168804,0.00260862,0.449882 kka2_1:1_W24A,kka2_1:1_24,Kka2,kka2_1:1,P00552,0.449924,NO,24,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-1.779,-3.385,1.606,,0.477,E,B,0.47,-0.21,2.375,,56.06,AHH,-2.24467,0.520039,0.00631564,0.449924 kka2_1:1_A25F,kka2_1:1_25,Kka2,kka2_1:1,P00552,0.449938,NO,25,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.496,-4.408,1.912,,0.427,E,B,0.46,-0.47,6.872,6.872,65.53,HHP,-2.15167,0.520039,0.00595636,0.449938 kka2_1:1_S32C,kka2_1:1_32,Kka2,kka2_1:1,P00552,0.449984,NO,32,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-0.804,-4.665,3.861,,0.768,S,b,0.27,3.75,,,,OPA,-1.74533,0.520039,0.00149998,0.449984 kka2_1:8_R143P,kka2_1:8_143,Kka2,kka2_1:8,P00552,0.449991,NO,143,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.525,-4.091,1.566,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.100394,0.00662247,0.449991 kka2_1:8_R143P,kka2_1:8_143,Kka2,kka2_1:8,P00552,0.449991,NO,143,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.525,-4.091,1.566,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.100394,0.00662247,0.449991 kka2_1:1_E59P,kka2_1:1_59,Kka2,kka2_1:1,P00552,0.450009,NO,59,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-0.952,-3.748,2.796,,0.187,.,L,1.04,0.62,2.648,,50.38,PAH,-1.53,0.520039,0.00280355,0.450009 kka2_1:8_C77L,kka2_1:8_77,Kka2,kka2_1:8,P00552,0.450079,NO,77,C,L,CL,Special,Hydrophobic,5.07,9.7088,4.6388,198,121,131,10,108.5,166.7,58.2,-1.477,-3.33,1.853,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.100394,0.00441216,0.450079 kka2_1:8_C77L,kka2_1:8_77,Kka2,kka2_1:8,P00552,0.450079,NO,77,C,L,CL,Special,Hydrophobic,5.07,9.7088,4.6388,198,121,131,10,108.5,166.7,58.2,-1.477,-3.33,1.853,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.100394,0.00441216,0.450079 beta-lactamase_M209G,beta-lactamase_209,TEM-1,beta-lactamase,P62593,0.450091,NO,209,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.442,-3.732,2.29,5.44502,,H,A,1.75,-0.97,1.402,,64.69,HHA,-1.52633,0.221079,0.00625021,0.450091 kka2_1:1_A87C,kka2_1:1_87,Kka2,kka2_1:1,P00552,0.450151,NO,87,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.917,-5.153,3.236,,1.039,S,L,0.46,1.57,20.738,20.738,65.53,AHO,-1.822,0.520039,0.00791281,0.450151 beta-lactamase_L219G,beta-lactamase_219,TEM-1,beta-lactamase,P62593,0.450182,NO,219,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.313,-3.865,2.552,5.74153,,I,A,0.84,-0.51,2.321,,74.48,HHB,-1.21533,0.221079,0.00664345,0.450182 kka2_1:4_Y244W,kka2_1:4_244,Kka2,kka2_1:4,P00552,0.45021,NO,244,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-0.775,-4.226,3.451,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.168804,0.00453187,0.45021 beta-lactamase_2500_A246V,beta-lactamase_2500_246,TEM-1,beta-lactamase_2500,P62593,0.450252,NO,246,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.121,-1.76,-0.361,,0.01,E,B,0.46,-1.01,0.753,,73.78,HHH,-1.55633,0.361275,0.00569458,0.450252 beta-lactamase_2500_L49K,beta-lactamase_2500_49,TEM-1,beta-lactamase_2500,P62593,0.450287,NO,49,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.897,-3.583,1.686,,0.131,T,A,0.55,0.04,6.681,,64.69,AHP,-1.99233,0.361275,0.00401477,0.450287 kka2_1:1_M120T,kka2_1:1_120,Kka2,kka2_1:1,P00552,0.45034,NO,120,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-3.877,-3.448,-0.429,,,H,A,0.55,-0.42,2.259,,92.05,HHB,-2.16733,0.520039,0.00265808,0.45034 kka2_1:1_L165C,kka2_1:1_165,Kka2,kka2_1:1,P00552,0.450341,NO,165,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-2.453,-5.171,2.718,,0.299,,B,1.59,1.12,2.47,,64.39,OHH,-1.90967,0.520039,0.00801161,0.450341 kka2_1:1_A172Q,kka2_1:1_172,Kka2,kka2_1:1,P00552,0.450357,NO,172,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.757,-3.279,1.522,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.520039,0.0079265,0.450357 beta-lactamase_2500_V260N,beta-lactamase_2500_260,TEM-1,beta-lactamase_2500,P62593,0.450374,NO,260,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.361275,0.00471757,0.450374 kka2_1:1_L47I,kka2_1:1_47,Kka2,kka2_1:1,P00552,0.450473,NO,47,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.265,-3.255,1.99,,0.139,E,B,0.55,-0.86,14.593,14.593,63.26,HHH,-1.77933,0.520039,0.00509386,0.450473 kka2_1:8_A215M,kka2_1:8_215,Kka2,kka2_1:8,P00552,0.450488,NO,215,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.968,-4.593,3.625,,0.039,E,B,1.04,-0.59,2.77,,50.38,HHA,-1.00467,0.100394,0.00529129,0.450488 kka2_1:8_A215M,kka2_1:8_215,Kka2,kka2_1:8,P00552,0.450488,NO,215,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.968,-4.593,3.625,,0.039,E,B,1.04,-0.59,2.77,,50.38,HHA,-1.00467,0.100394,0.00529129,0.450488 kka2_1:1_Q61S,kka2_1:1_61,Kka2,kka2_1:1,P00552,0.450544,NO,61,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.982,-2.728,-0.254,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.520039,0.00612092,0.450544 kka2_1:4_P179D,kka2_1:4_179,Kka2,kka2_1:4,P00552,0.450544,NO,179,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.974,-3.655,2.681,,0.113,,B,0.52,0.69,10.913,10.913,56.06,HOA,-2.19867,0.168804,0.00298346,0.450544 beta-lactamase_T131Q,beta-lactamase_131,TEM-1,beta-lactamase,P62593,0.450561,NO,131,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.328,-3.951,2.623,5.0548,,H,A,0.53,-0.69,3.306,,67.48,PPH,-1.00867,0.221079,0.00345886,0.450561 kka2_1:1_M178G,kka2_1:1_178,Kka2,kka2_1:1,P00552,0.450581,NO,178,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-3.206,-2.978,-0.228,,0.554,.,b,0.55,0.68,3.152,,71.59,BHO,-2.154,0.520039,0.00717253,0.450581 kka2_1:4_K112P,kka2_1:4_112,Kka2,kka2_1:4,P00552,0.450603,NO,112,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-2.491,-4.121,1.63,,0.076,H,A,2.34,-1.37,0.39,,56.06,ABH,-2.00133,0.168804,0.00645389,0.450603 beta-lactamase_625_S266P,beta-lactamase_625_266,TEM-1,beta-lactamase_625,P62593,0.450705,NO,266,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.213352,0.0140785,0.450705 PSD95pdz3_I336R,PSD95pdz3_336,PSD95pdz3,PSD95pdz3,P31016,0.45086,NO,336,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.63,-3.84,2.21,5.11321,,,,,13.6363,,,,OHH,-1.38733,0.0758425,0.000887923,0.45086 kka2_1:8_L223A,kka2_1:8_223,Kka2,kka2_1:8,P00552,0.450883,NO,223,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.861,-3.151,2.29,,,H,A,1.59,-1.24,1.017,,50,HHH,-0.854333,0.100394,0.00253574,0.450883 kka2_1:8_L223A,kka2_1:8_223,Kka2,kka2_1:8,P00552,0.450883,NO,223,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.861,-3.151,2.29,,,H,A,1.59,-1.24,1.017,,50,HHH,-0.854333,0.100394,0.00253574,0.450883 E1_Ubiquitin_I44S,E1_Ubiquitin_44,Uba1,E1_Ubiquitin,P0CG63,0.450928,NO,44,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.432,-3.475,2.043,,,E,B,0.27,-1.17,4.57,,78.74,HHH,-1.25633,0.18783,0.00209731,0.450928 E1_Ubiquitin_R42G,E1_Ubiquitin_42,Uba1,E1_Ubiquitin,P0CG63,0.450928,NO,42,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.302,-3.229,1.927,,0.244,E,B,,-0.54,,,,PBH,-1.24667,0.18783,0.00224033,0.450928 hsp90_N588V,hsp90_588,hsp90,hsp90,P02829,0.450975,NO,588,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-3.051,-2.682,0,4.61142,0.019,H,A,0.14,0.39,,,,HPH,-3.12167,0.368192,0.000222939,0.450975 beta-lactamase_625_G114E,beta-lactamase_625_114,TEM-1,beta-lactamase_625,P62593,0.451009,NO,114,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.094,-3.605,2.511,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.213352,0.00224919,0.451009 kka2_1:4_L67F,kka2_1:4_67,Kka2,kka2_1:4,P00552,0.451054,NO,67,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.741,-3.645,2.904,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.168804,0.00102787,0.451054 gb1_D272P,gb1_272,gb1,gb1,P06654,0.451092,NO,272,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.457,-3.572,2.115,,,,,,,0.234,,11.83,HAA,-1.54533,0.177985,0.00218257,0.451092 gb1_T281P,gb1_281,gb1,gb1,P06654,0.451092,NO,281,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.828,-3.589,1.761,,,,,,,1.038,,35.71,HPA,-1.63667,0.177985,0.00284418,0.451092 beta-lactamase_625_E35R,beta-lactamase_625_35,TEM-1,beta-lactamase_625,P62593,0.451102,NO,35,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-0.869,-3.551,2.682,,0.15,H,A,1.04,0.21,0.664,,46.85,HAA,-1.88667,0.213352,0.00174441,0.451102 beta-lactamase_2500_Y103C,beta-lactamase_2500_103,TEM-1,beta-lactamase_2500,P62593,0.451112,NO,103,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-1.33,-5.047,3.717,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.361275,0.00443048,0.451112 kka2_1:1_A13P,kka2_1:1_13,Kka2,kka2_1:1,P00552,0.451139,NO,13,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.248,-2.481,0.233,,0.689,G,A,0.46,0.99,25.015,25.015,92.05,OHH,-1.646,0.520039,0.00784241,0.451139 kka2_1:2_W15V,kka2_1:2_15,Kka2,kka2_1:2,P00552,0.45118,NO,15,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-1.392,-3.309,1.917,,0.01,G,A,0.47,0.15,2.586,,52.27,HHH,-2.10533,0.295029,0.00585505,0.45118 beta-lactamase_156_D177E,beta-lactamase_156_177,TEM-1,beta-lactamase_156,P62593,0.451211,NO,177,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.967,-2.98,2.013,,0.006,T,L,0.75,-1.02,2.072,,64.69,BAP,-0.873667,0.111618,0.000864022,0.451211 beta-lactamase_2500_S266K,beta-lactamase_2500_266,TEM-1,beta-lactamase_2500,P62593,0.451301,NO,266,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.361275,0.0140785,0.451301 kka2_1:2_R217V,kka2_1:2_217,Kka2,kka2_1:2,P00552,0.451386,NO,217,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.158,-3.458,2.3,,0.252,T,A,1.2,-0.59,0.381,,52.27,ABH,-1.127,0.295029,0.0047191,0.451386 beta-lactamase_625_A123D,beta-lactamase_625_123,TEM-1,beta-lactamase_625,P62593,0.451444,NO,123,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.834,-3.743,2.909,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.213352,0.0010157,0.451444 beta-lactamase_2500_T107I,beta-lactamase_2500_107,TEM-1,beta-lactamase_2500,P62593,0.451485,NO,107,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.117,-3.664,2.547,,,G,A,0.22,-0.06,2.686,,67.83,HPA,-1.265,0.361275,0.00239347,0.451485 beta-lactamase_625_E35T,beta-lactamase_625_35,TEM-1,beta-lactamase_625,P62593,0.451565,NO,35,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-0.869,-3.447,2.578,,0.15,H,A,1.04,0.21,0.664,,46.85,HAA,-1.88667,0.213352,0.00174441,0.451565 Ubiquitin_E34Y,Ubiquitin_34,Uba1,Ubiquitin,P0CG48,0.451613,NO,34,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.294,-4.235,2.941,5.02178,0.406,H,A,1.62,0.6,1.295,,35.62,BAO,-1.24933,0.205827,0.000686048,0.451613 Ubiquitin_F45K,Ubiquitin_45,Uba1,Ubiquitin,P0CG48,0.451613,NO,45,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.322,-3.862,2.54,4.80693,0.26,E,B,1.62,-0.99,1.531,,53.87,HHH,-1.55267,0.205827,0.000470401,0.451613 Ubiquitin_I36W,Ubiquitin_36,Uba1,Ubiquitin,P0CG48,0.451613,NO,36,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.477,-5.37,3.893,5.1035,0.203,,B,0.27,-0.22,1.552,,30.8,OHO,-1.30767,0.205827,0.000630555,0.451613 Ubiquitin_L56W,Ubiquitin_56,Uba1,Ubiquitin,P0CG48,0.451613,NO,56,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.324,-5.191,3.867,4.83362,,T,A,,-0.91,,,,PHP,-1.60067,0.205827,0.000459465,0.451613 Ubiquitin_L73M,Ubiquitin_73,Uba1,Ubiquitin,P0CG48,0.451613,NO,73,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.801,-4.364,2.563,5.27116,0.518,,B,0.77,1,10.519,10.519,34.31,BHB,-1.858,0.205827,0.000710624,0.451613 Ubiquitin_Q41Y,Ubiquitin_41,Uba1,Ubiquitin,P0CG48,0.451613,NO,41,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-1.329,-3.882,2.553,4.9201,0.017,E,B,0.12,-0.98,0.812,,30.07,PPB,-1.55067,0.205827,0.000521668,0.451613 Ubiquitin_R42Q,Ubiquitin_42,Uba1,Ubiquitin,P0CG48,0.451613,NO,42,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.571,-2.82,1.249,5.07805,0.244,E,B,0.68,-0.54,1.976,,72.85,PBH,-1.38967,0.205827,0.000622265,0.451613 kka2_1:1_L107K,kka2_1:1_107,Kka2,kka2_1:1,P00552,0.451702,NO,107,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.238,-3.819,2.581,,0.197,.,B,0.55,-1.1,3.542,,71.59,BHH,-2.143,0.520039,0.00561937,0.451702 kka2_1:1_L107T,kka2_1:1_107,Kka2,kka2_1:1,P00552,0.451702,NO,107,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.238,-2.585,1.347,,0.197,.,B,0.55,-1.1,3.542,,71.59,BHH,-2.143,0.520039,0.00561937,0.451702 kka2_1:1_L212R,kka2_1:1_212,Kka2,kka2_1:1,P00552,0.451712,NO,212,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.904,-4.001,3.097,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.520039,0.0031426,0.451712 beta-lactamase_2500_D48H,beta-lactamase_2500_48,TEM-1,beta-lactamase_2500,P62593,0.451735,NO,48,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.101,-2.659,1.558,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.361275,0.0027273,0.451735 beta-lactamase_2500_R273W,beta-lactamase_2500_273,TEM-1,beta-lactamase_2500,P62593,0.451828,NO,273,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.314,-5.456,3.142,,0.564,H,A,1.2,1.57,19.943,19.943,73.78,ABP,-1.841,0.361275,0.0077952,0.451828 beta-lactamase_I256T,beta-lactamase_256,TEM-1,beta-lactamase,P62593,0.451833,NO,256,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.621,-2.85,1.229,5.3196,,E,B,1,-0.84,1.615,,73.08,BHH,-1.80667,0.221079,0.00710634,0.451833 beta-lactamase_625_V72M,beta-lactamase_625_72,TEM-1,beta-lactamase_625,P62593,0.451838,NO,72,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.658,-4.404,2.746,,,H,A,0.44,-1.03,0.981,,65.73,BHH,-1.32167,0.213352,0.00501194,0.451838 kka2_1:4_A129P,kka2_1:4_129,Kka2,kka2_1:4,P00552,0.451894,NO,129,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.656,-4.009,2.353,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.168804,0.00726862,0.451894 kka2_1:4_V36T,kka2_1:4_36,Kka2,kka2_1:4,P00552,0.451901,NO,36,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-0.898,-3.307,2.409,,0.292,E,B,0.44,0.21,0.278,,52.27,HHH,-1.484,0.168804,0.00245633,0.451901 kka2_1:8_F48C,kka2_1:8_48,Kka2,kka2_1:8,P00552,0.451916,NO,48,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.453,-4.951,3.498,,0.296,E,B,1.62,-0.99,14.194,14.194,55.3,HHH,-1.444,0.100394,0.00475422,0.451916 kka2_1:8_F48C,kka2_1:8_48,Kka2,kka2_1:8,P00552,0.451916,NO,48,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.453,-4.951,3.498,,0.296,E,B,1.62,-0.99,14.194,14.194,55.3,HHH,-1.444,0.100394,0.00475422,0.451916 kka2_1:1_G99D,kka2_1:1_99,Kka2,kka2_1:1,P00552,0.451922,NO,99,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.596,-3.497,2.901,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.520039,0.00186055,0.451922 kka2_1:4_T125Y,kka2_1:4_125,Kka2,kka2_1:4,P00552,0.451943,NO,125,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.622,-4.422,1.8,,0.791,T,A,0.82,0.33,1.612,,92.05,BPH,-1.56933,0.168804,0.00821755,0.451943 Pab1_G167I,Pab1_167,Pab1,Pab1,P04147,0.452011,NO,167,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.223,-3.902,2.679,,0.195,S,g,,0.03,,,,BOH,-1.25133,0.175299,0.00146449,0.452011 beta-lactamase_2500_E87H,beta-lactamase_2500_87,TEM-1,beta-lactamase_2500,P62593,0.452029,NO,87,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.421,-4.575,3.154,,0.048,,B,1.04,0.92,17.923,17.923,64.69,PAP,-1.969,0.361275,0.00337888,0.452029 kka2_1:1_G181K,kka2_1:1_181,Kka2,kka2_1:1,P00552,0.452068,NO,181,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-2.698,-3.658,0.96,,0.379,S,B,0.75,0.78,15.356,15.356,71.59,AOA,-2.21,0.520039,0.00728319,0.452068 beta-lactamase_39_D155K,beta-lactamase_39_155,TEM-1,beta-lactamase_39,P62593,0.452071,NO,155,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.889,-3.426,2.537,,0.049,,B,0.75,-0.9,3.208,,64.69,OAB,-1.62267,0.0495842,0.00135315,0.452071 kka2_1:1_P179Y,kka2_1:1_179,Kka2,kka2_1:1,P00552,0.4521,NO,179,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.974,-4.379,3.405,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.520039,0.00298346,0.4521 beta-lactamase_156_G85P,beta-lactamase_156_85,TEM-1,beta-lactamase_156,P62593,0.452125,NO,85,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.011,-3.891,2.88,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.111618,0.00252173,0.452125 kka2_1:1_W24S,kka2_1:1_24,Kka2,kka2_1:1,P00552,0.452126,NO,24,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-1.779,-2.861,1.082,,0.477,E,B,0.47,-0.21,2.375,,56.06,AHH,-2.24467,0.520039,0.00631564,0.452126 beta-lactamase_625_T179A,beta-lactamase_625_179,TEM-1,beta-lactamase_625,P62593,0.452127,NO,179,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.085,-2.334,1.249,,,E,B,0.22,-1.38,0.367,,73.08,PPH,-1.557,0.213352,0.00226045,0.452127 kka2_1:4_R140E,kka2_1:4_140,Kka2,kka2_1:4,P00552,0.452251,NO,140,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.351,-3.33,1.979,,0.12,H,A,1.2,0.2,2.561,,53.03,BBH,-1.885,0.168804,0.00430167,0.452251 beta-lactamase_0_S128E,beta-lactamase_0_128,TEM-1,beta-lactamase_0,P62593,0.452261,NO,128,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-0.84,-3.215,2.375,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.0500837,0.00071483,0.452261 beta-lactamase_2500_V82D,beta-lactamase_2500_82,TEM-1,beta-lactamase_2500,P62593,0.452261,NO,82,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.325,-3.879,2.554,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.361275,0.00397046,0.452261 beta-lactamase_625_V117Q,beta-lactamase_625_117,TEM-1,beta-lactamase_625,P62593,0.452307,NO,117,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.53,-4.247,2.717,,,H,A,0.44,-0.34,1.23,,65.03,PHB,-1.741,0.213352,0.00467906,0.452307 kka2_1:4_A237T,kka2_1:4_237,Kka2,kka2_1:4,P00552,0.452358,NO,237,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.12,-2.777,0.657,,0.068,H,A,0.46,-0.71,2.444,,92.05,HHA,-2.10433,0.168804,0.012257,0.452358 beta-lactamase_625_P65C,beta-lactamase_625_65,TEM-1,beta-lactamase_625,P62593,0.452374,NO,65,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.894,-5.01,4.116,,0.098,E,B,0.52,-0.62,0.3,,40.56,HOH,-1.03233,0.213352,0.00152776,0.452374 kka2_1:2_R140F,kka2_1:2_140,Kka2,kka2_1:2,P00552,0.452426,NO,140,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.351,-4.407,3.056,,0.12,H,A,1.2,0.2,0.352,,53.03,BBH,-1.885,0.295029,0.00430167,0.452426 kka2_1:1_S114L,kka2_1:1_114,Kka2,kka2_1:1,P00552,0.452439,NO,114,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.527,-3.038,0.511,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.520039,0.00705262,0.452439 beta-lactamase_2500_L223F,beta-lactamase_2500_223,TEM-1,beta-lactamase_2500,P62593,0.452454,NO,223,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.055,-2.724,1.669,,0.27,,B,0.55,0.09,1.334,,74.48,HHO,-1.35033,0.361275,0.00372793,0.452454 beta-lactamase_625_L136T,beta-lactamase_625_136,TEM-1,beta-lactamase_625,P62593,0.452509,NO,136,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.232,-3.487,2.255,,,H,A,0.55,-0.34,0.336,,48.95,HHH,-1.088,0.213352,0.00442304,0.452509 beta-lactamase_2500_A133C,beta-lactamase_2500_133,TEM-1,beta-lactamase_2500,P62593,0.452519,NO,133,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.186,-4.706,3.52,,,H,A,0.46,-0.86,2.649,,67.83,HHP,-0.988333,0.361275,0.00468022,0.452519 kka2_1:8_D183L,kka2_1:8_183,Kka2,kka2_1:8,P00552,0.452613,NO,183,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.204,-3.71,2.506,,0.518,.,b,0.75,0.25,0.347,,52.27,AAH,-1.40533,0.100394,0.00426304,0.452613 kka2_1:8_D183L,kka2_1:8_183,Kka2,kka2_1:8,P00552,0.452613,NO,183,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.204,-3.71,2.506,,0.518,.,b,0.75,0.25,0.347,,52.27,AAH,-1.40533,0.100394,0.00426304,0.452613 beta-lactamase_2500_T27H,beta-lactamase_2500_27,TEM-1,beta-lactamase_2500,P62593,0.452621,NO,27,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.905,-4.62,2.715,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.361275,0.00306559,0.452621 beta-lactamase_2500_D212V,beta-lactamase_2500_212,TEM-1,beta-lactamase_2500,P62593,0.452773,NO,212,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.624,-3.608,1.984,,0.037,,b,0.75,-0.58,12.482,,74.48,HAB,-1.77667,0.361275,0.00644302,0.452773 kka2_1:1_R140E,kka2_1:1_140,Kka2,kka2_1:1,P00552,0.452776,NO,140,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.351,-3.33,1.979,,0.12,H,A,1.2,0.2,11.345,11.345,53.03,BBH,-1.885,0.520039,0.00430167,0.452776 beta-lactamase_625_M115H,beta-lactamase_625_115,TEM-1,beta-lactamase_625,P62593,0.452874,NO,115,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.389,-4.759,3.37,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.213352,0.0034337,0.452874 beta-lactamase_2500_L219P,beta-lactamase_2500_219,TEM-1,beta-lactamase_2500,P62593,0.452942,NO,219,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.313,-4.214,2.901,,,I,A,0.55,-0.51,35.994,35.994,74.48,HHB,-1.21533,0.361275,0.00664345,0.452942 kka2_1:1_E161F,kka2_1:1_161,Kka2,kka2_1:1,P00552,0.452952,NO,161,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.581,-4.379,2.798,,0.829,G,A,1.04,2.24,1.612,,92.05,AAB,-1.861,0.520039,0.00760103,0.452952 kka2_1:1_E160F,kka2_1:1_160,Kka2,kka2_1:1,P00552,0.452969,NO,160,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.683,-4.47,2.787,,0.989,G,A,1.04,2.28,0.273,,71.59,AAA,-1.36133,0.520039,0.00935762,0.452969 kka2_1:1_G10S,kka2_1:1_10,Kka2,kka2_1:1,P00552,0.453028,NO,10,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.921,-3.23,1.309,,,,,,,1.862,,71.59,HOP,-2.10733,0.520039,0.00289233,0.453028 beta-lactamase_2500_A124M,beta-lactamase_2500_124,TEM-1,beta-lactamase_2500,P62593,0.453088,NO,124,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.181,-4.519,3.338,,,H,A,0.46,-0.9,0.314,,64.34,HHH,-1.152,0.361275,0.00481399,0.453088 beta-lactamase_39_M184R,beta-lactamase_39_184,TEM-1,beta-lactamase_39,P62593,0.453093,NO,184,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.593,-3.928,2.335,,,H,A,0.55,-0.87,2.893,,62.94,HHH,-1.41,0.0495842,0.00356019,0.453093 kka2_1:2_V36M,kka2_1:2_36,Kka2,kka2_1:2,P00552,0.453107,NO,36,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-0.898,-4.103,3.205,,0.292,E,B,1.48,0.21,1.064,,52.27,HHH,-1.484,0.295029,0.00245633,0.453107 kka2_1:1_R18T,kka2_1:1_18,Kka2,kka2_1:1,P00552,0.453124,NO,18,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.055,-2.928,0.873,,0.474,T,A,1.2,0.54,11.422,11.422,71.59,ABH,-1.821,0.520039,0.00724065,0.453124 kka2_1:1_P109K,kka2_1:1_109,Kka2,kka2_1:1,P00552,0.45314,NO,109,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.412,-3.629,2.217,,0.376,H,A,0.52,-1.25,18.506,18.506,65.53,HOH,-1.84567,0.520039,0.0070929,0.45314 kka2_1:1_P109M,kka2_1:1_109,Kka2,kka2_1:1,P00552,0.45314,NO,109,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.412,-4.773,3.361,,0.376,H,A,0.52,-1.25,18.506,18.506,65.53,HOH,-1.84567,0.520039,0.0070929,0.45314 kka2_1:1_G201M,kka2_1:1_201,Kka2,kka2_1:1,P00552,0.453204,NO,201,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.56,-4.972,3.412,,0.149,T,l,0.29,-0.57,16.092,16.092,52.65,POB,-1.92233,0.520039,0.00820117,0.453204 WW_domain_Y188F,WW_domain_188,Yap65,WW_domain,P46937,0.453205,NO,188,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-1.326,-1.972,0.646,5.89734,,,,,,,,,BHH,-1.45333,0.153962,0.00265487,0.453205 kka2_1:1_A224P,kka2_1:1_224,Kka2,kka2_1:1,P00552,0.453224,NO,224,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.977,-3.784,2.807,,,H,A,0.46,-1.26,1.725,,63.64,HHP,-1.41033,0.520039,0.00352047,0.453224 kka2_1:1_A172H,kka2_1:1_172,Kka2,kka2_1:1,P00552,0.453281,NO,172,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.757,-4.807,3.05,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.520039,0.0079265,0.453281 kka2_1:4_E111P,kka2_1:4_111,Kka2,kka2_1:4,P00552,0.45331,NO,111,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.28,-4.066,1.786,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.168804,0.00746789,0.45331 beta-lactamase_2500_V82L,beta-lactamase_2500_82,TEM-1,beta-lactamase_2500,P62593,0.453331,NO,82,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.325,-2.426,1.101,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.361275,0.00397046,0.453331 beta-lactamase_0_D231K,beta-lactamase_0_231,TEM-1,beta-lactamase_0,P62593,0.45334,NO,231,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.816,-3.42,2.604,,,E,B,0.75,-1.06,4.975,,65.38,HAB,-0.994,0.0500837,0.00107395,0.45334 kka2_1:2_D220P,kka2_1:2_220,Kka2,kka2_1:2,P00552,0.453343,NO,220,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.787,-3.727,2.94,,,H,A,0.75,-1.14,0.745,,46.59,PAH,-1.152,0.295029,0.00158066,0.453343 kka2_1:2_D220S,kka2_1:2_220,Kka2,kka2_1:2,P00552,0.453343,NO,220,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.787,-3.25,2.463,,,H,A,0.75,-1.14,0.745,,46.59,PAH,-1.152,0.295029,0.00158066,0.453343 beta-lactamase_2500_T131Y,beta-lactamase_2500_131,TEM-1,beta-lactamase_2500,P62593,0.453364,NO,131,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.328,-4.285,2.957,,,H,A,0.22,-0.69,3.048,,67.48,PPH,-1.00867,0.361275,0.00345886,0.453364 kka2_1:8_V49R,kka2_1:8_49,Kka2,kka2_1:8,P00552,0.453404,NO,49,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.614,-4.154,2.54,,,E,B,1.48,-0.77,1.31,,64.39,HHB,-1.3,0.100394,0.00615685,0.453404 kka2_1:8_V49R,kka2_1:8_49,Kka2,kka2_1:8,P00552,0.453404,NO,49,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.614,-4.154,2.54,,,E,B,1.48,-0.77,1.31,,64.39,HHB,-1.3,0.100394,0.00615685,0.453404 kka2_1:4_D183V,kka2_1:4_183,Kka2,kka2_1:4,P00552,0.45341,NO,183,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.204,-2.92,1.716,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.168804,0.00426304,0.45341 kka2_1:1_K175G,kka2_1:1_175,Kka2,kka2_1:1,P00552,0.453416,NO,175,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-2.897,-3.762,0.865,,0.579,H,A,1.3,0.51,9.33,9.33,71.59,HBH,-1.82333,0.520039,0.00693093,0.453416 beta-lactamase_D48W,beta-lactamase_48,TEM-1,beta-lactamase,P62593,0.453485,NO,48,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.101,-5.502,4.401,4.89966,0.189,E,B,0.23,0.21,1.281,,50.35,HAH,-1.62467,0.221079,0.0027273,0.453485 kka2_1:2_Y244F,kka2_1:2_244,Kka2,kka2_1:2,P00552,0.453549,NO,244,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-0.775,-2.97,2.195,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.295029,0.00453187,0.453549 kka2_1:4_P179E,kka2_1:4_179,Kka2,kka2_1:4,P00552,0.453555,NO,179,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.974,-3.589,2.615,,0.113,,B,0.52,0.69,10.913,10.913,56.06,HOA,-2.19867,0.168804,0.00298346,0.453555 kka2_1:2_R140T,kka2_1:2_140,Kka2,kka2_1:2,P00552,0.453561,NO,140,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.351,-2.806,1.455,,0.12,H,A,1.2,0.2,0.352,,53.03,BBH,-1.885,0.295029,0.00430167,0.453561 kka2_1:1_C31W,kka2_1:1_31,Kka2,kka2_1:1,P00552,0.453573,NO,31,C,W,CW,Special,Hydrophobic,5.07,5.89,0.82,215,121,204,83,108.5,227.8,119.3,-2.246,-5.453,3.207,,1.152,S,b,0.46,4.16,8.272,,63.26,OOP,-1.21533,0.520039,0.00681582,0.453573 kka2_1:2_L212C,kka2_1:2_212,Kka2,kka2_1:2,P00552,0.453626,NO,212,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.904,-4.688,3.784,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.295029,0.0031426,0.453626 kka2_1:1_C209D,kka2_1:1_209,Kka2,kka2_1:1,P00552,0.45375,NO,209,C,D,CD,Special,negativeCharge,5.07,5.0516,-0.0184,154,121,133,12,108.5,111.1,2.6,-0.906,-3.991,3.085,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.520039,0.00260862,0.45375 beta-lactamase_156_V117W,beta-lactamase_156_117,TEM-1,beta-lactamase_156,P62593,0.453757,NO,117,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.53,-5.228,3.698,,,H,A,0.44,-0.34,1.182,,65.03,PHB,-1.741,0.111618,0.00467906,0.453757 kka2_1:1_A166W,kka2_1:1_166,Kka2,kka2_1:1,P00552,0.453778,NO,166,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.407,-5.55,3.143,,0.534,.,B,0.46,1.03,1.147,,71.59,HHO,-2.421,0.520039,0.00799912,0.453778 beta-lactamase_625_I93R,beta-lactamase_625_93,TEM-1,beta-lactamase_625,P62593,0.453861,NO,93,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.401,-4.203,2.802,,0.128,E,B,0.48,0.44,1.524,,67.83,BHB,-1.873,0.213352,0.00527066,0.453861 kka2_1:1_G55A,kka2_1:1_55,Kka2,kka2_1:1,P00552,0.453936,NO,55,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.625,-2.457,0.832,,0.517,S,b,0.29,1.19,4.035,,63.64,POH,-2.05967,0.520039,0.00667877,0.453936 beta-lactamase_L47N,beta-lactamase_47,TEM-1,beta-lactamase,P62593,0.453979,NO,47,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.876,-3.972,2.096,5.27297,0.007,E,B,1.07,0.2,1.244,,67.83,AHA,-1.639,0.221079,0.00439844,0.453979 beta-lactamase_L73W,beta-lactamase_73,TEM-1,beta-lactamase,P62593,0.453979,NO,73,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.507,-5.171,3.664,5.84139,,H,A,1.75,-0.64,2.09,,67.83,HHH,-1.487,0.221079,0.00488983,0.453979 kka2_1:1_I207M,kka2_1:1_207,Kka2,kka2_1:1,P00552,0.45399,NO,207,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.175,-4.117,2.942,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.520039,0.00611824,0.45399 kka2_1:2_E230N,kka2_1:2_230,Kka2,kka2_1:2,P00552,0.454007,NO,230,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.672,-3.821,1.149,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.295029,0.00920051,0.454007 beta-lactamase_2500_G141V,beta-lactamase_2500_141,TEM-1,beta-lactamase_2500,P62593,0.454025,NO,141,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.828,-3.79,2.962,,0.575,T,l,0.29,-0.28,1.493,,64.69,HOO,-1.08933,0.361275,0.0012419,0.454025 kka2_1:4_C31T,kka2_1:4_31,Kka2,kka2_1:4,P00552,0.454085,NO,31,C,T,CT,Special,Polar,5.07,5.6,0.53,149,121,119,-2,108.5,116.1,7.6,-2.246,-3.606,1.36,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.168804,0.00681582,0.454085 kka2_1:4_D183S,kka2_1:4_183,Kka2,kka2_1:4,P00552,0.454091,NO,183,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.204,-3.317,2.113,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.168804,0.00426304,0.454091 Pab1_K131E,Pab1_131,Pab1,Pab1,P04147,0.454122,NO,131,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.083,-2.807,1.724,,0.462,E,B,1.82,0.57,,,,HBP,-1.12467,0.175299,0.000349395,0.454122 kka2_1:1_P98K,kka2_1:1_98,Kka2,kka2_1:1,P00552,0.454126,NO,98,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.526,-2.937,1.411,,0.391,S,B,0.52,-0.65,1.521,,63.26,HOO,-1.19167,0.520039,0.00622754,0.454126 kka2_1:2_A224K,kka2_1:2_224,Kka2,kka2_1:2,P00552,0.454176,NO,224,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.977,-3.586,2.609,,,H,A,0.46,-1.26,1.646,,63.64,HHP,-1.41033,0.295029,0.00352047,0.454176 kka2_1:4_W69T,kka2_1:4_69,Kka2,kka2_1:4,P00552,0.454217,NO,69,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-0.859,-3.698,2.839,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.168804,0.0012874,0.454217 kka2_1:1_E17S,kka2_1:1_17,Kka2,kka2_1:1,P00552,0.454222,NO,17,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.154,-2.653,0.499,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.520039,0.00688738,0.454222 beta-lactamase_2500_G265P,beta-lactamase_2500_265,TEM-1,beta-lactamase_2500,P62593,0.454241,NO,265,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.361275,0.00811926,0.454241 beta-lactamase_2500_A215W,beta-lactamase_2500_215,TEM-1,beta-lactamase_2500,P62593,0.454247,NO,215,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.503,-5.336,3.833,,,,a,0.46,-0.93,3.516,,74.48,HHO,-1.42633,0.361275,0.00544007,0.454247 kka2_1:1_A168C,kka2_1:1_168,Kka2,kka2_1:1,P00552,0.454342,NO,168,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.989,-5.174,3.185,,0.67,H,A,0.46,0.15,25.546,25.546,64.39,OHA,-2.12933,0.520039,0.00806773,0.454342 kka2_1:2_Q219V,kka2_1:2_219,Kka2,kka2_1:2,P00552,0.454371,NO,219,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-0.93,-3.601,2.671,,0.088,H,A,0.4,-0.85,1.917,,50,HPA,-1.05167,0.295029,0.00237913,0.454371 kka2_1:1_C209L,kka2_1:1_209,Kka2,kka2_1:1,P00552,0.454403,NO,209,C,L,CL,Special,Hydrophobic,5.07,9.7088,4.6388,198,121,131,10,108.5,166.7,58.2,-0.906,-2.447,1.541,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.520039,0.00260862,0.454403 E1_Ubiquitin_R72A,E1_Ubiquitin_72,Uba1,E1_Ubiquitin,P0CG63,0.454465,NO,72,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.184,-2.895,1.711,,0.077,,B,0.16,-0.1,,,,HBH,-1.08733,0.18783,0.00129853,0.454465 beta-lactamase_625_M115F,beta-lactamase_625_115,TEM-1,beta-lactamase_625,P62593,0.454502,NO,115,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.389,-2.82,1.431,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.213352,0.0034337,0.454502 beta-lactamase_2500_R91E,beta-lactamase_2500_91,TEM-1,beta-lactamase_2500,P62593,0.454519,NO,91,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.392,-2.211,0.819,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.361275,0.00380226,0.454519 kka2_1:8_G205R,kka2_1:8_205,Kka2,kka2_1:8,P00552,0.454522,NO,205,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.596,-3.961,3.365,,,E,b,0.75,-1.05,,,,POH,-1.09933,0.100394,0.00221855,0.454522 kka2_1:8_G205R,kka2_1:8_205,Kka2,kka2_1:8,P00552,0.454522,NO,205,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.596,-3.961,3.365,,,E,b,0.75,-1.05,,,,POH,-1.09933,0.100394,0.00221855,0.454522 beta-lactamase_2500_T27M,beta-lactamase_2500_27,TEM-1,beta-lactamase_2500,P62593,0.454527,NO,27,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.905,-4.581,2.676,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.361275,0.00306559,0.454527 kka2_1:1_G205L,kka2_1:1_205,Kka2,kka2_1:1,P00552,0.454529,NO,205,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.596,-3.836,3.24,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.520039,0.00221855,0.454529 beta-lactamase_2500_R220C,beta-lactamase_2500_220,TEM-1,beta-lactamase_2500,P62593,0.454547,NO,220,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-0.942,-5.009,4.067,,0.295,I,A,1.2,-0.76,2.175,,74.48,HBP,-1.33633,0.361275,0.00232421,0.454547 kka2_1:2_P194G,kka2_1:2_194,Kka2,kka2_1:2,P00552,0.45455,NO,194,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.846,-3.359,2.513,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.295029,0.00314194,0.45455 beta-lactamase_R202D,beta-lactamase_202,TEM-1,beta-lactamase,P62593,0.454571,NO,202,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.292,-3.594,2.302,5.16273,0.188,H,A,0.68,0.62,1.918,,77.62,PBP,-1.54767,0.221079,0.00321899,0.454571 kka2_1:1_A129I,kka2_1:1_129,Kka2,kka2_1:1,P00552,0.45459,NO,129,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.656,-3.236,1.58,,0.845,G,A,0.46,0.72,19.686,19.686,92.05,OHP,-1.99,0.520039,0.00726862,0.45459 kka2_1:2_E96N,kka2_1:2_96,Kka2,kka2_1:2,P00552,0.454594,NO,96,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.573,-3.878,1.305,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.295029,0.00369441,0.454594 kka2_1:2_I207N,kka2_1:2_207,Kka2,kka2_1:2,P00552,0.4547,NO,207,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.175,-4.238,3.063,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.295029,0.00611824,0.4547 kka2_1:4_M197T,kka2_1:4_197,Kka2,kka2_1:4,P00552,0.454722,NO,197,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.707,-2.639,0.932,,0.121,E,B,0.55,-1.19,0.415,,65.53,HHH,-1.847,0.168804,0.00921295,0.454722 kka2_1:1_L184T,kka2_1:1_184,Kka2,kka2_1:1,P00552,0.454732,NO,184,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.496,-3.677,2.181,,0.489,E,B,0.55,-0.06,19.127,19.127,63.26,AHH,-1.24833,0.520039,0.00518742,0.454732 kka2_1:1_N58Y,kka2_1:1_58,Kka2,kka2_1:1,P00552,0.454767,NO,58,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-2.641,-4.48,1.839,,0.131,S,A,0.61,0.72,30.755,30.755,71.59,HPA,-1.83033,0.520039,0.00793425,0.454767 kka2_1:2_L223D,kka2_1:2_223,Kka2,kka2_1:2,P00552,0.454786,NO,223,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.861,-4.172,3.311,,,H,A,0.55,-1.24,0.266,,50,HHH,-0.854333,0.295029,0.00253574,0.454786 kka2_1:2_T125F,kka2_1:2_125,Kka2,kka2_1:2,P00552,0.454805,NO,125,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.622,-4.443,1.821,,0.791,T,A,0.22,0.33,2.029,,92.05,BPH,-1.56933,0.295029,0.00821755,0.454805 beta-lactamase_39_K232V,beta-lactamase_39_232,TEM-1,beta-lactamase_39,P62593,0.454837,NO,232,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.012,-3.626,2.614,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.0495842,0.00313441,0.454837 kka2_1:1_D134C,kka2_1:1_134,Kka2,kka2_1:1,P00552,0.454846,NO,134,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.969,-5.129,4.16,,0.421,B,B,0.75,0.31,2.329,,49.62,HAB,-1.057,0.520039,0.00270812,0.454846 beta-lactamase_156_G249K,beta-lactamase_156_249,TEM-1,beta-lactamase_156,P62593,0.454868,NO,249,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.111618,0.00220169,0.454868 kka2_1:4_S105P,kka2_1:4_105,Kka2,kka2_1:4,P00552,0.454871,NO,105,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.945,-3.155,1.21,,0.056,S,B,0.77,-1.04,3.442,,65.53,PPB,-2.17033,0.168804,0.00847233,0.454871 beta-lactamase_2500_S104C,beta-lactamase_2500_104,TEM-1,beta-lactamase_2500,P62593,0.454888,NO,104,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.015,-2.945,1.93,,0.04,,b,0.27,0.57,1.133,,63.29,HPO,-1.05267,0.361275,0.00218083,0.454888 beta-lactamase_2500_R257L,beta-lactamase_2500_257,TEM-1,beta-lactamase_2500,P62593,0.454895,NO,257,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.361275,0.00756629,0.454895 kka2_1:1_I221Q,kka2_1:1_221,Kka2,kka2_1:1,P00552,0.454997,NO,221,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.739,-4.324,2.585,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.520039,0.00945908,0.454997 kka2_1:1_P132I,kka2_1:1_132,Kka2,kka2_1:1,P00552,0.455004,NO,132,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.775,-4.037,3.262,,0.692,.,A,0.52,0.56,0.224,,44.7,OOH,-0.825667,0.520039,0.0018489,0.455004 kka2_1:4_C31Y,kka2_1:4_31,Kka2,kka2_1:4,P00552,0.455009,NO,31,C,Y,CY,Special,Hydrophobic,5.07,5.66,0.59,194,121,181,60,108.5,193.6,85.1,-2.246,-4.264,2.018,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.168804,0.00681582,0.455009 kka2_1:4_D157Y,kka2_1:4_157,Kka2,kka2_1:4,P00552,0.455009,NO,157,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.993,-4.444,3.451,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.168804,0.0042313,0.455009 kka2_1:2_I221C,kka2_1:2_221,Kka2,kka2_1:2,P00552,0.455015,NO,221,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.739,-4.79,3.051,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.295029,0.00945908,0.455015 kka2_1:4_A237Q,kka2_1:4_237,Kka2,kka2_1:4,P00552,0.45502,NO,237,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.12,-4.238,2.118,,0.068,H,A,0.46,-0.71,2.444,,92.05,HHA,-2.10433,0.168804,0.012257,0.45502 kka2_1:1_L67V,kka2_1:1_67,Kka2,kka2_1:1,P00552,0.455025,NO,67,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.741,-2.882,2.141,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.520039,0.00102787,0.455025 beta-lactamase_625_L218G,beta-lactamase_625_218,TEM-1,beta-lactamase_625,P62593,0.455105,NO,218,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.391,-3.644,2.253,,,I,b,0.55,-0.53,17.202,17.202,74.48,OHH,-1.58867,0.213352,0.00618274,0.455105 kka2_1:1_Q219P,kka2_1:1_219,Kka2,kka2_1:1,P00552,0.455239,NO,219,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-0.93,-3.727,2.797,,0.088,H,A,0.4,-0.85,1.917,,50,HPA,-1.05167,0.520039,0.00237913,0.455239 beta-lactamase_2500_T69S,beta-lactamase_2500_69,TEM-1,beta-lactamase_2500,P62593,0.455255,NO,69,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-0.973,-2.405,1.432,,,G,A,0.22,-1.24,2.05,,93.01,PPH,-1.01833,0.361275,0.00127498,0.455255 beta-lactamase_2500_T107G,beta-lactamase_2500_107,TEM-1,beta-lactamase_2500,P62593,0.455279,NO,107,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.117,-3.227,2.11,,,G,A,0.22,-0.06,2.686,,67.83,HPA,-1.265,0.361275,0.00239347,0.455279 beta-lactamase_625_L28D,beta-lactamase_625_28,TEM-1,beta-lactamase_625,P62593,0.455369,NO,28,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.579,-3.96,2.381,,0.277,H,A,0.55,-0.16,2.716,,93.01,PHH,-2.11333,0.213352,0.00359321,0.455369 Pab1_F129N,Pab1_129,Pab1,Pab1,P04147,0.455434,NO,129,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.269,-3.934,2.665,,0.219,E,B,0.03,-0.07,1.307,,73.83,HHH,-1.27533,0.175299,0.000625182,0.455434 beta-lactamase_2500_R91G,beta-lactamase_2500_91,TEM-1,beta-lactamase_2500,P62593,0.455494,NO,91,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.392,-3.437,2.045,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.361275,0.00380226,0.455494 beta-lactamase_L205T,beta-lactamase_205,TEM-1,beta-lactamase,P62593,0.455502,NO,205,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.922,-3.476,2.554,5.67023,,H,A,1.3,-0.46,0.678,,42.31,PHH,-1.57767,0.221079,0.00255802,0.455502 kka2_1:4_A129I,kka2_1:4_129,Kka2,kka2_1:4,P00552,0.455619,NO,129,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.656,-3.236,1.58,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.168804,0.00726862,0.455619 kka2_1:1_S105Q,kka2_1:1_105,Kka2,kka2_1:1,P00552,0.455639,NO,105,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.945,-3.245,1.3,,0.056,S,B,0.27,-1.04,3.442,,65.53,PPB,-2.17033,0.520039,0.00847233,0.455639 kka2_1:4_L70R,kka2_1:4_70,Kka2,kka2_1:4,P00552,0.455765,NO,70,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.017,-4.037,3.02,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.168804,0.00411884,0.455765 beta-lactamase_625_E87R,beta-lactamase_625_87,TEM-1,beta-lactamase_625,P62593,0.455767,NO,87,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.421,-3.739,2.318,,0.048,,B,1.04,0.92,17.923,17.923,64.69,PAP,-1.969,0.213352,0.00337888,0.455767 gb1_Y229G,gb1_229,gb1,gb1,P06654,0.455896,NO,229,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-1.282,-3.319,2.037,,,,,,,,,,PHB,-1.4915,0.177985,0.00366605,0.455896 beta-lactamase_2500_Y103R,beta-lactamase_2500_103,TEM-1,beta-lactamase_2500,P62593,0.45591,NO,103,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-1.33,-3.864,2.534,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.361275,0.00443048,0.45591 Pab1_I152G,Pab1_152,Pab1,Pab1,P04147,0.455911,NO,152,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.345,-3.622,2.277,,0.165,E,B,1.23,-0.71,1.288,,71.4,AHH,-1.59433,0.175299,0.000740963,0.455911 beta-lactamase_156_L223D,beta-lactamase_156_223,TEM-1,beta-lactamase_156,P62593,0.455961,NO,223,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.055,-4.067,3.012,,0.27,,B,0.55,0.09,1.511,,74.48,HHO,-1.35033,0.111618,0.00372793,0.455961 kka2_1:1_L223K,kka2_1:1_223,Kka2,kka2_1:1,P00552,0.456033,NO,223,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.861,-3.793,2.932,,,H,A,0.55,-1.24,1.268,,50,HHH,-0.854333,0.520039,0.00253574,0.456033 kka2_1:8_L107D,kka2_1:8_107,Kka2,kka2_1:8,P00552,0.456076,NO,107,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.238,-3.01,1.772,,0.197,.,B,0.55,-1.1,4.478,,71.59,BHH,-2.143,0.100394,0.00561937,0.456076 kka2_1:8_L107D,kka2_1:8_107,Kka2,kka2_1:8,P00552,0.456076,NO,107,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.238,-3.01,1.772,,0.197,.,B,0.55,-1.1,4.478,,71.59,BHH,-2.143,0.100394,0.00561937,0.456076 kka2_1:1_A129M,kka2_1:1_129,Kka2,kka2_1:1,P00552,0.456078,NO,129,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.656,-4.824,3.168,,0.845,G,A,0.46,0.72,19.686,19.686,92.05,OHP,-1.99,0.520039,0.00726862,0.456078 beta-lactamase_156_I258S,beta-lactamase_156_258,TEM-1,beta-lactamase_156,P62593,0.456133,NO,258,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.111618,0.007931,0.456133 beta-lactamase_A132C,beta-lactamase_132,TEM-1,beta-lactamase,P62593,0.4562,NO,132,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.9,-4.503,3.603,4.58504,,H,A,2.34,-0.93,2.217,,64.69,PHH,-1.138,0.221079,0.000962524,0.4562 beta-lactamase_D212M,beta-lactamase_212,TEM-1,beta-lactamase,P62593,0.4562,NO,212,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.624,-4.83,3.206,4.9705,0.037,,b,1.3,-0.58,12.482,,74.48,HAB,-1.77667,0.221079,0.00644302,0.4562 beta-lactamase_P143D,beta-lactamase_143,TEM-1,beta-lactamase,P62593,0.4562,NO,143,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.967,-3.622,2.655,5.16366,0.075,H,A,0.99,-0.37,0.479,,66.78,OOB,-1.354,0.221079,0.00114551,0.4562 kka2_1:1_T225H,kka2_1:1_225,Kka2,kka2_1:1,P00552,0.456228,NO,225,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.393,-3.458,1.065,,0.036,H,A,0.22,-1.22,4.554,,63.64,HPB,-1.58733,0.520039,0.0113598,0.456228 kka2_1:4_P132I,kka2_1:4_132,Kka2,kka2_1:4,P00552,0.456229,NO,132,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.775,-4.037,3.262,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.168804,0.0018489,0.456229 kka2_1:4_A119P,kka2_1:4_119,Kka2,kka2_1:4,P00552,0.456284,NO,119,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.073,-3.813,2.74,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.168804,0.00441074,0.456284 beta-lactamase_156_M184N,beta-lactamase_156_184,TEM-1,beta-lactamase_156,P62593,0.456289,NO,184,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.593,-4.028,2.435,,,H,A,0.55,-0.87,1.671,,62.94,HHH,-1.41,0.111618,0.00356019,0.456289 kka2_1:1_A14D,kka2_1:1_14,Kka2,kka2_1:1,P00552,0.456321,NO,14,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.837,-2.812,0.975,,0.728,G,A,0.46,0.7,1.17,,71.59,HHH,-1.82567,0.520039,0.00706614,0.456321 kka2_1:4_A224E,kka2_1:4_224,Kka2,kka2_1:4,P00552,0.45633,NO,224,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.977,-3.569,2.592,,,H,A,0.46,-1.26,0.93,,63.64,HHP,-1.41033,0.168804,0.00352047,0.45633 kka2_1:1_D208E,kka2_1:1_208,Kka2,kka2_1:1,P00552,0.456331,NO,208,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.708,-2.793,2.085,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.520039,0.00212588,0.456331 beta-lactamase_2500_R220Q,beta-lactamase_2500_220,TEM-1,beta-lactamase_2500,P62593,0.456397,NO,220,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-0.942,-3.517,2.575,,0.295,I,A,1.2,-0.76,2.175,,74.48,HBP,-1.33633,0.361275,0.00232421,0.456397 kka2_1:4_I221Q,kka2_1:4_221,Kka2,kka2_1:4,P00552,0.456408,NO,221,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.739,-4.324,2.585,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.168804,0.00945908,0.456408 kka2_1:8_G189S,kka2_1:8_189,Kka2,kka2_1:8,P00552,0.45642,NO,189,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.596,-3.189,2.593,,0.034,S,l,0.75,-0.99,,,,BOA,-0.739,0.100394,0.00253688,0.45642 kka2_1:8_G189S,kka2_1:8_189,Kka2,kka2_1:8,P00552,0.45642,NO,189,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.596,-3.189,2.593,,0.034,S,l,0.75,-0.99,,,,BOA,-0.739,0.100394,0.00253688,0.45642 kka2_1:2_D134R,kka2_1:2_134,Kka2,kka2_1:2,P00552,0.456426,NO,134,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.969,-3.942,2.973,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.295029,0.00270812,0.456426 kka2_1:2_P132H,kka2_1:2_132,Kka2,kka2_1:2,P00552,0.456471,NO,132,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.775,-4.706,3.931,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.295029,0.0018489,0.456471 beta-lactamase_625_I244E,beta-lactamase_625_244,TEM-1,beta-lactamase_625,P62593,0.456507,NO,244,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.555,-3.795,2.24,,,E,B,0.48,-0.84,2.061,,77.62,OHH,-1.385,0.213352,0.00605379,0.456507 beta-lactamase_625_T187Y,beta-lactamase_625_187,TEM-1,beta-lactamase_625,P62593,0.456518,NO,187,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.401,-4.271,2.87,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.213352,0.00491782,0.456518 kka2_1:4_L126E,kka2_1:4_126,Kka2,kka2_1:4,P00552,0.456533,NO,126,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.246,-3.857,2.611,,0.285,S,B,0.55,0.12,0.302,,51.89,PHA,-1.744,0.168804,0.0066485,0.456533 beta-lactamase_2500_E166P,beta-lactamase_2500_166,TEM-1,beta-lactamase_2500,P62593,0.45662,NO,166,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.756,-3.897,2.141,,0.508,G,A,1.04,1.05,2.124,,73.08,OAH,-1.42233,0.361275,0.00512989,0.45662 kka2_1:4_A108F,kka2_1:4_108,Kka2,kka2_1:4,P00552,0.456621,NO,108,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.061,-4.427,2.366,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.168804,0.00751209,0.456621 beta-lactamase_156_L284W,beta-lactamase_156_284,TEM-1,beta-lactamase_156,P62593,0.456644,NO,284,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.111618,0.0686156,0.456644 kka2_1:1_Q163T,kka2_1:1_163,Kka2,kka2_1:1,P00552,0.456704,NO,163,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.162,-2.589,0.427,,0.58,T,B,0.64,1.85,2.779,,64.02,BPO,-1.78333,0.520039,0.00719507,0.456704 kka2_1:1_A117Y,kka2_1:1_117,Kka2,kka2_1:1,P00552,0.456738,NO,117,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.828,-4.189,3.361,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.520039,0.00282984,0.456738 kka2_1:1_T225M,kka2_1:1_225,Kka2,kka2_1:1,P00552,0.456747,NO,225,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.393,-3.418,1.025,,0.036,H,A,0.22,-1.22,4.554,,63.64,HPB,-1.58733,0.520039,0.0113598,0.456747 beta-lactamase_D161K,beta-lactamase_161,TEM-1,beta-lactamase,P62593,0.456796,NO,161,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.891,-3.426,2.535,5.12208,0.341,,A,0.23,-0.52,1.602,,61.19,HAB,-0.961333,0.221079,0.000897697,0.456796 beta-lactamase_2500_R159M,beta-lactamase_2500_159,TEM-1,beta-lactamase_2500,P62593,0.456814,NO,159,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-0.94,-4.529,3.589,,0.316,,B,1.2,-0.55,2.341,,64.34,PBH,-1.011,0.361275,0.00108472,0.456814 kka2_1:1_G6H,kka2_1:1_6,Kka2,kka2_1:1,P00552,0.456931,NO,6,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.685,-4.557,2.872,,,,,,,1.292,,71.59,AOH,-1.639,0.520039,0.00204693,0.456931 kka2_1:4_E262C,kka2_1:4_262,Kka2,kka2_1:4,P00552,0.456943,NO,262,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-0.829,-5.339,4.51,,0.059,G,A,1.04,-0.18,2.383,,42.42,AAH,-0.816,0.168804,0.0191586,0.456943 kka2_1:4_E262W,kka2_1:4_262,Kka2,kka2_1:4,P00552,0.456943,NO,262,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-0.829,-5.349,4.52,,0.059,G,A,1.04,-0.18,2.383,,42.42,AAH,-0.816,0.168804,0.0191586,0.456943 kka2_1:2_R140M,kka2_1:2_140,Kka2,kka2_1:2,P00552,0.456956,NO,140,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.351,-4.639,3.288,,0.12,H,A,1.2,0.2,0.352,,53.03,BBH,-1.885,0.295029,0.00430167,0.456956 kka2_1:2_L174V,kka2_1:2_174,Kka2,kka2_1:2,P00552,0.456963,NO,174,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.952,-2.256,1.304,,,H,A,1.59,-0.31,8.521,,51.89,BHB,-2.08533,0.295029,0.00438501,0.456963 kka2_1:1_D238S,kka2_1:1_238,Kka2,kka2_1:1,P00552,0.456973,NO,238,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.83,-2.933,0.103,,0.604,H,A,0.75,-0.33,11.329,11.329,92.05,HAB,-2.633,0.520039,0.0113863,0.456973 kka2_1:1_A222Y,kka2_1:1_222,Kka2,kka2_1:1,P00552,0.456987,NO,222,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.725,-4.191,3.466,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.520039,0.00207657,0.456987 PSD95pdz3_H372N,PSD95pdz3_372,PSD95pdz3,PSD95pdz3,P31016,0.45703,NO,372,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-1.627,-2.905,1.278,5.5607,,,,,17.008,,,,PBA,-1.63033,0.0758425,0.00040301,0.45703 kka2_1:1_E142P,kka2_1:1_142,Kka2,kka2_1:1,P00552,0.457083,NO,142,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.221,-2.43,0.209,,0.471,H,A,1.52,0.85,3.626,,65.53,HAB,-2.08033,0.520039,0.00748883,0.457083 kka2_1:8_Y22E,kka2_1:8_22,Kka2,kka2_1:8,P00552,0.457113,NO,22,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-1.583,-3.743,2.16,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.100394,0.00598977,0.457113 kka2_1:8_Y22E,kka2_1:8_22,Kka2,kka2_1:8,P00552,0.457113,NO,22,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-1.583,-3.743,2.16,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.100394,0.00598977,0.457113 kka2_1:1_E111P,kka2_1:1_111,Kka2,kka2_1:1,P00552,0.457141,NO,111,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.28,-4.066,1.786,,0.155,H,A,1.52,-1.14,15.716,15.716,65.53,HAB,-2.27833,0.520039,0.00746789,0.457141 kka2_1:1_I29K,kka2_1:1_29,Kka2,kka2_1:1,P00552,0.457145,NO,29,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.692,-3.779,2.087,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.520039,0.00619521,0.457145 beta-lactamase_39_E61P,beta-lactamase_39_61,TEM-1,beta-lactamase_39,P62593,0.457179,NO,61,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.115,-3.861,1.746,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.0495842,0.00440955,0.457179 kka2_1:4_L93Q,kka2_1:4_93,Kka2,kka2_1:4,P00552,0.45719,NO,93,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.815,-4.083,3.268,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.168804,0.00131498,0.45719 kka2_1:4_F263V,kka2_1:4_263,Kka2,kka2_1:4,P00552,0.457316,NO,263,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-0.911,-3.287,2.376,,0.006,G,A,0.58,-0.12,2.284,,45.83,AHH,-0.92,0.168804,0.0172454,0.457316 kka2_1:1_K112P,kka2_1:1_112,Kka2,kka2_1:1,P00552,0.457405,NO,112,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-2.491,-4.121,1.63,,0.076,H,A,2.34,-1.37,23.433,23.433,56.06,ABH,-2.00133,0.520039,0.00645389,0.457405 beta-lactamase_2500_P143G,beta-lactamase_2500_143,TEM-1,beta-lactamase_2500,P62593,0.457433,NO,143,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.967,-3.499,2.532,,0.075,H,A,0.52,-0.37,0.479,,66.78,OOB,-1.354,0.361275,0.00114551,0.457433 beta-lactamase_156_T107Y,beta-lactamase_156_107,TEM-1,beta-lactamase_156,P62593,0.457589,NO,107,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.117,-4.214,3.097,,,G,A,0.22,-0.06,0.341,,67.83,HPA,-1.265,0.111618,0.00239347,0.457589 kka2_1:1_F263V,kka2_1:1_263,Kka2,kka2_1:1,P00552,0.457624,NO,263,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-0.911,-3.287,2.376,,0.006,G,A,0.58,-0.12,2.284,,45.83,AHH,-0.92,0.520039,0.0172454,0.457624 Pab1_S154I,Pab1_154,Pab1,Pab1,P04147,0.457627,NO,154,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.146,-3.602,2.456,,0.208,E,B,0.1,-0.75,,,,HPP,-1.408,0.175299,0.000319331,0.457627 kka2_1:1_P167G,kka2_1:1_167,Kka2,kka2_1:1,P00552,0.45764,NO,167,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-2.403,-3.388,0.985,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.520039,0.00543203,0.45764 kka2_1:2_L174G,kka2_1:2_174,Kka2,kka2_1:2,P00552,0.457655,NO,174,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.952,-3.755,2.803,,,H,A,1.59,-0.31,8.521,,51.89,BHB,-2.08533,0.295029,0.00438501,0.457655 beta-lactamase_625_S241Y,beta-lactamase_625_241,TEM-1,beta-lactamase_625,P62593,0.457729,NO,241,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.213352,0.00452736,0.457729 kka2_1:1_L170G,kka2_1:1_170,Kka2,kka2_1:1,P00552,0.457744,NO,170,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.28,-3.713,2.433,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.520039,0.00730791,0.457744 kka2_1:1_L170Y,kka2_1:1_170,Kka2,kka2_1:1,P00552,0.457744,NO,170,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.28,-4.115,2.835,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.520039,0.00730791,0.457744 kka2_1:1_L126E,kka2_1:1_126,Kka2,kka2_1:1,P00552,0.457783,NO,126,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.246,-3.857,2.611,,0.285,S,B,0.55,0.12,0.302,,51.89,PHA,-1.744,0.520039,0.0066485,0.457783 beta-lactamase_625_V72E,beta-lactamase_625_72,TEM-1,beta-lactamase_625,P62593,0.457813,NO,72,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.658,-3.755,2.097,,,H,A,0.44,-1.03,0.981,,65.73,BHH,-1.32167,0.213352,0.00501194,0.457813 kka2_1:1_V49K,kka2_1:1_49,Kka2,kka2_1:1,P00552,0.457951,NO,49,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.614,-3.819,2.205,,,E,B,0.44,-0.77,3.665,3.665,64.39,HHB,-1.3,0.520039,0.00615685,0.457951 kka2_1:2_V185E,kka2_1:2_185,Kka2,kka2_1:2,P00552,0.458011,NO,185,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.045,-3.799,2.754,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.295029,0.00367031,0.458011 kka2_1:1_A64P,kka2_1:1_64,Kka2,kka2_1:1,P00552,0.458052,NO,64,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.496,-4.02,2.524,,0.039,H,A,0.46,-0.57,1.175,,56.06,AHH,-1.334,0.520039,0.00705578,0.458052 kka2_1:1_M116C,kka2_1:1_116,Kka2,kka2_1:1,P00552,0.458073,NO,116,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-2.482,-3.43,0.948,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.520039,0.00745147,0.458073 beta-lactamase_E35H,beta-lactamase_35,TEM-1,beta-lactamase,P62593,0.458079,NO,35,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-0.869,-4.279,3.41,5.10723,0.15,H,A,0.52,0.21,1.081,,46.85,HAA,-1.88667,0.221079,0.00174441,0.458079 beta-lactamase_I229T,beta-lactamase_229,TEM-1,beta-lactamase,P62593,0.458079,NO,229,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.267,-2.621,1.354,5.0911,0.083,E,B,1,-0.76,1.114,,50,HHH,-1.58767,0.221079,0.00477249,0.458079 beta-lactamase_V31F,beta-lactamase_31,TEM-1,beta-lactamase,P62593,0.458079,NO,31,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.822,-2.736,0.914,5.43781,,H,A,2.78,-0.46,2.885,,73.78,BHB,-2.03767,0.221079,0.00478065,0.458079 beta-lactamase_625_G240H,beta-lactamase_625_240,TEM-1,beta-lactamase_625,P62593,0.458093,NO,240,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.213352,0.00591201,0.458093 kka2_1:2_L170E,kka2_1:2_170,Kka2,kka2_1:2,P00552,0.458109,NO,170,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.28,-3.891,2.611,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.295029,0.00730791,0.458109 kka2_1:2_I29K,kka2_1:2_29,Kka2,kka2_1:2,P00552,0.458151,NO,29,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.692,-3.779,2.087,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.295029,0.00619521,0.458151 beta-lactamase_V78Y,beta-lactamase_78,TEM-1,beta-lactamase,P62593,0.458154,NO,78,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.459,-4.112,2.653,4.79197,,H,A,0.96,-0.47,1.132,,63.64,HHH,-1.17833,0.221079,0.00492501,0.458154 kka2_1:8_F256E,kka2_1:8_256,Kka2,kka2_1:8,P00552,0.458217,NO,256,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.49,-3.921,2.431,,,H,A,1.62,-0.78,1.713,,53.03,HHH,-1.423,0.100394,0.0132841,0.458217 kka2_1:8_F256E,kka2_1:8_256,Kka2,kka2_1:8,P00552,0.458217,NO,256,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.49,-3.921,2.431,,,H,A,1.62,-0.78,1.713,,53.03,HHH,-1.423,0.100394,0.0132841,0.458217 kka2_1:1_G151T,kka2_1:1_151,Kka2,kka2_1:1,P00552,0.458228,NO,151,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.873,-3.611,2.738,,0.678,T,l,0.29,1.36,0.226,,49.62,HOH,-1.11433,0.520039,0.00339918,0.458228 kka2_1:1_M197K,kka2_1:1_197,Kka2,kka2_1:1,P00552,0.458271,NO,197,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.707,-3.81,2.103,,0.121,E,B,1.59,-1.19,2.097,,65.53,HHH,-1.847,0.520039,0.00921295,0.458271 Pab1_I137K,Pab1_137,Pab1,Pab1,P04147,0.458365,NO,137,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.212,-3.724,2.512,,0.068,,B,0.77,0.35,,,,AHA,-1.314,0.175299,0.000342224,0.458365 kka2_1:2_P98H,kka2_1:2_98,Kka2,kka2_1:2,P00552,0.458369,NO,98,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.526,-4.763,3.237,,0.391,S,B,0.52,-0.65,2.82,,63.26,HOO,-1.19167,0.295029,0.00622754,0.458369 beta-lactamase_2500_I93N,beta-lactamase_2500_93,TEM-1,beta-lactamase_2500,P62593,0.458407,NO,93,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.401,-4.175,2.774,,0.128,E,B,0.48,0.44,19.374,19.374,67.83,BHB,-1.873,0.361275,0.00527066,0.458407 kka2_1:4_L184T,kka2_1:4_184,Kka2,kka2_1:4,P00552,0.458507,NO,184,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.496,-3.677,2.181,,0.489,E,B,1.59,-0.06,4.495,,63.26,AHH,-1.24833,0.168804,0.00518742,0.458507 kka2_1:4_W15Y,kka2_1:4_15,Kka2,kka2_1:4,P00552,0.458608,NO,15,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-1.392,-3.559,2.167,,0.01,G,A,0.47,0.15,0.943,,52.27,HHH,-2.10533,0.168804,0.00585505,0.458608 kka2_1:1_L7A,kka2_1:1_7,Kka2,kka2_1:1,P00552,0.458637,NO,7,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.926,-3.033,1.107,,,,,,,18.934,18.934,71.59,OHB,-2.12333,0.520039,0.00269456,0.458637 kka2_1:1_G88D,kka2_1:1_88,Kka2,kka2_1:1,P00552,0.458681,NO,88,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.689,-2.184,0.495,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.520039,0.00685559,0.458681 kka2_1:1_V185E,kka2_1:1_185,Kka2,kka2_1:1,P00552,0.458701,NO,185,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.045,-3.799,2.754,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.520039,0.00367031,0.458701 beta-lactamase_2500_G154L,beta-lactamase_2500_154,TEM-1,beta-lactamase_2500,P62593,0.458756,NO,154,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.823,-3.779,2.956,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.361275,0.00180205,0.458756 kka2_1:2_V113L,kka2_1:2_113,Kka2,kka2_1:2,P00552,0.458808,NO,113,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.233,-2.374,1.141,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.295029,0.00650191,0.458808 kka2_1:1_L47W,kka2_1:1_47,Kka2,kka2_1:1,P00552,0.458869,NO,47,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.265,-5.21,3.945,,0.139,E,B,0.55,-0.86,14.593,14.593,63.26,HHH,-1.77933,0.520039,0.00509386,0.458869 kka2_1:4_E59V,kka2_1:4_59,Kka2,kka2_1:4,P00552,0.458869,NO,59,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-0.952,-3.591,2.639,,0.187,.,L,1.04,0.62,3.408,,50.38,PAH,-1.53,0.168804,0.00280355,0.458869 beta-lactamase_2500_R63F,beta-lactamase_2500_63,TEM-1,beta-lactamase_2500,P62593,0.458941,NO,63,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-0.943,-4.214,3.271,,0.218,,B,1.2,-0.31,0.929,,44.06,ABH,-0.992333,0.361275,0.00126938,0.458941 kka2_1:1_L260R,kka2_1:1_260,Kka2,kka2_1:1,P00552,0.458941,NO,260,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.741,-3.961,3.22,,0.022,H,A,0.55,-0.52,,,,HHA,-0.845667,0.520039,0.0233782,0.458941 kka2_1:1_P45M,kka2_1:1_45,Kka2,kka2_1:1,P00552,0.459011,NO,45,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.774,-4.81,3.036,,0.669,.,B,0.52,-0.76,4.882,,71.59,BOH,-2.152,0.520039,0.00590481,0.459011 kka2_1:2_F256Q,kka2_1:2_256,Kka2,kka2_1:2,P00552,0.459046,NO,256,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.49,-4.227,2.737,,,H,A,0.58,-0.78,1.653,,53.03,HHH,-1.423,0.295029,0.0132841,0.459046 beta-lactamase_2500_A235N,beta-lactamase_2500_235,TEM-1,beta-lactamase_2500,P62593,0.459069,NO,235,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.266,-3.746,2.48,,0.32,E,B,0.46,-0.86,0.891,,50,OHO,-0.89,0.361275,0.00493474,0.459069 beta-lactamase_625_D174H,beta-lactamase_625_174,TEM-1,beta-lactamase_625,P62593,0.459146,NO,174,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.738,-4.455,3.717,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.213352,0.00125633,0.459146 kka2_1:1_A119C,kka2_1:1_119,Kka2,kka2_1:1,P00552,0.459175,NO,119,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.073,-4.641,3.568,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.520039,0.00441074,0.459175 kka2_1:1_A119K,kka2_1:1_119,Kka2,kka2_1:1,P00552,0.459175,NO,119,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.073,-3.574,2.501,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.520039,0.00441074,0.459175 kka2_1:1_R226A,kka2_1:1_226,Kka2,kka2_1:1,P00552,0.459283,NO,226,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.392,-3.272,1.88,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.520039,0.0108032,0.459283 kka2_1:1_R226V,kka2_1:1_226,Kka2,kka2_1:1,P00552,0.459283,NO,226,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.392,-3.893,2.501,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.520039,0.0108032,0.459283 kka2_1:1_D157N,kka2_1:1_157,Kka2,kka2_1:1,P00552,0.459327,NO,157,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.993,-2.434,1.441,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.520039,0.0042313,0.459327 kka2_1:2_H188R,kka2_1:2_188,Kka2,kka2_1:2,P00552,0.459333,NO,188,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-0.913,-3.509,2.596,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.295029,0.00273139,0.459333 kka2_1:1_D127G,kka2_1:1_127,Kka2,kka2_1:1,P00552,0.459367,NO,127,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.364,-3.377,2.013,,0.573,.,B,0.75,0.45,3.414,,50.38,HAO,-1.51067,0.520039,0.00660501,0.459367 kka2_1:1_D154A,kka2_1:1_154,Kka2,kka2_1:1,P00552,0.45941,NO,154,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.876,-3.364,2.488,,0.457,.,b,0.75,1.48,0.658,,52.65,HAP,-1.52467,0.520039,0.00292633,0.45941 kka2_1:2_F256C,kka2_1:2_256,Kka2,kka2_1:2,P00552,0.459446,NO,256,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.49,-3.289,1.799,,,H,A,0.58,-0.78,1.653,,53.03,HHH,-1.423,0.295029,0.0132841,0.459446 beta-lactamase_156_S233W,beta-lactamase_156_233,TEM-1,beta-lactamase_156,P62593,0.459527,NO,233,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.886,-5.339,3.453,,0.016,E,B,0.27,-1.01,4.111,,77.62,BPO,-1.17267,0.111618,0.00311415,0.459527 beta-lactamase_2500_R159E,beta-lactamase_2500_159,TEM-1,beta-lactamase_2500,P62593,0.459587,NO,159,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-0.94,-3.241,2.301,,0.316,,B,1.2,-0.55,2.341,,64.34,PBH,-1.011,0.361275,0.00108472,0.459587 beta-lactamase_625_A34H,beta-lactamase_625_34,TEM-1,beta-lactamase_625,P62593,0.459666,NO,34,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.059,-4.883,2.824,,,H,A,0.46,-0.54,3.614,,73.78,AHA,-1.74967,0.213352,0.00407913,0.459666 kka2_1:1_I228L,kka2_1:1_228,Kka2,kka2_1:1,P00552,0.459666,NO,228,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.142,-1.811,0.669,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.520039,0.00458834,0.459666 Ubiquitin_I23H,Ubiquitin_23,Uba1,Ubiquitin,P0CG48,0.459677,NO,23,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.325,-4.881,3.556,4.67534,,H,A,0.01,-0.93,0.515,,52.12,PHA,-1.54033,0.205827,0.000621252,0.459677 Ubiquitin_I23N,Ubiquitin_23,Uba1,Ubiquitin,P0CG48,0.459677,NO,23,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.325,-4.087,2.762,4.67534,,H,A,0.01,-0.93,0.515,,52.12,PHA,-1.54033,0.205827,0.000621252,0.459677 Ubiquitin_L15R,Ubiquitin_15,Uba1,Ubiquitin,P0CG48,0.459677,NO,15,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.082,-4.03,2.948,5.14718,0.029,E,B,1.16,-0.53,0.936,,38.69,PHA,-1.40833,0.205827,0.000519738,0.459677 Ubiquitin_L67R,Ubiquitin_67,Uba1,Ubiquitin,P0CG48,0.459677,NO,67,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.435,-2.966,1.531,4.92156,,E,B,1.19,-1.02,6.371,6.371,30.8,PHB,-1.628,0.205827,0.000482727,0.459677 Ubiquitin_L8A,Ubiquitin_8,Uba1,Ubiquitin,P0CG48,0.459677,NO,8,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.723,-2.624,0.901,5.28016,0.664,T,A,0.08,-0.34,0.664,,29.05,PHP,-1.51567,0.205827,0.000726165,0.459677 beta-lactamase_625_A40Y,beta-lactamase_625_40,TEM-1,beta-lactamase_625,P62593,0.459693,NO,40,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.402,-4.322,2.92,,0.155,S,B,0.46,0.21,1.357,,73.78,OHB,-1.40267,0.213352,0.00490026,0.459693 beta-lactamase_625_A235E,beta-lactamase_625_235,TEM-1,beta-lactamase_625,P62593,0.4598,NO,235,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.266,-3.558,2.292,,0.32,E,B,0.46,-0.86,0.281,,50,OHO,-0.89,0.213352,0.00493474,0.4598 kka2_1:1_F133C,kka2_1:1_133,Kka2,kka2_1:1,P00552,0.459919,NO,133,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-0.871,-4.914,4.043,,0.178,.,B,0.58,0.43,1.999,,42.42,OHA,-0.871667,0.520039,0.00182168,0.459919 beta-lactamase_2500_A132G,beta-lactamase_2500_132,TEM-1,beta-lactamase_2500,P62593,0.45995,NO,132,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.9,-3.009,2.109,,,H,A,0.46,-0.93,8.408,,64.69,PHH,-1.138,0.361275,0.000962524,0.45995 kka2_1:2_H188S,kka2_1:2_188,Kka2,kka2_1:2,P00552,0.459956,NO,188,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-0.913,-3.412,2.499,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.295029,0.00273139,0.459956 kka2_1:1_E149T,kka2_1:1_149,Kka2,kka2_1:1,P00552,0.459957,NO,149,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.994,-3.656,1.662,,0.674,H,A,1.04,1.63,3.671,,71.59,HAH,-1.59667,0.520039,0.00803343,0.459957 kka2_1:4_F263L,kka2_1:4_263,Kka2,kka2_1:4,P00552,0.460011,NO,263,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-0.911,-2.161,1.25,,0.006,G,A,0.58,-0.12,2.284,,45.83,AHH,-0.92,0.168804,0.0172454,0.460011 kka2_1:8_W69M,kka2_1:8_69,Kka2,kka2_1:8,P00552,0.460014,NO,69,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-0.859,-4.531,3.672,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.100394,0.0012874,0.460014 kka2_1:8_W69M,kka2_1:8_69,Kka2,kka2_1:8,P00552,0.460014,NO,69,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-0.859,-4.531,3.672,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.100394,0.0012874,0.460014 kka2_1:2_W91V,kka2_1:2_91,Kka2,kka2_1:2,P00552,0.460042,NO,91,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-1.178,-3.738,2.56,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.295029,0.00358653,0.460042 beta-lactamase_625_G142R,beta-lactamase_625_142,TEM-1,beta-lactamase_625,P62593,0.460082,NO,142,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.707,-3.93,3.223,,0.034,,p,0.29,-0.64,1.35,,64.69,OOO,-0.834,0.213352,0.00060149,0.460082 kka2_1:1_L70V,kka2_1:1_70,Kka2,kka2_1:1,P00552,0.460089,NO,70,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.017,-2.461,1.444,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.520039,0.00411884,0.460089 kka2_1:1_Y257H,kka2_1:1_257,Kka2,kka2_1:1,P00552,0.460119,NO,257,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-1.064,-4.042,2.978,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.520039,0.0148191,0.460119 beta-lactamase_2500_L197R,beta-lactamase_2500_197,TEM-1,beta-lactamase_2500,P62593,0.460147,NO,197,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.853,-3.93,3.077,,0.007,S,B,0.55,0.33,2.421,,60.14,HHP,-1.833,0.361275,0.00144602,0.460147 beta-lactamase_2500_H110D,beta-lactamase_2500_110,TEM-1,beta-lactamase_2500,P62593,0.460163,NO,110,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-1.706,-3.678,1.972,,0.341,G,a,0.17,1.08,31.31,31.31,64.69,BBH,-1.73333,0.361275,0.00441499,0.460163 WW_domain_R203C,WW_domain_203,Yap65,WW_domain,P46937,0.46026,NO,203,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.539,-4.857,3.318,5.41321,,,,,,1.9,,70.04,OBO,-1.4695,0.153962,0.00172433,0.46026 beta-lactamase_2500_G43S,beta-lactamase_2500_43,TEM-1,beta-lactamase_2500,P62593,0.460328,NO,43,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.62,-3.161,2.541,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.361275,0.00120151,0.460328 kka2_1:1_I207T,kka2_1:1_207,Kka2,kka2_1:1,P00552,0.46034,NO,207,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.175,-3.466,2.291,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.520039,0.00611824,0.46034 beta-lactamase_625_N168R,beta-lactamase_625_168,TEM-1,beta-lactamase_625,P62593,0.460353,NO,168,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-1.029,-3.58,2.551,,0.113,G,A,0.61,-0.4,1.014,,44.41,HPA,-1.13233,0.213352,0.00288667,0.460353 beta-lactamase_625_R273W,beta-lactamase_625_273,TEM-1,beta-lactamase_625,P62593,0.460387,NO,273,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.314,-5.456,3.142,,0.564,H,A,1.2,1.57,1.455,,73.78,ABP,-1.841,0.213352,0.0077952,0.460387 beta-lactamase_2500_E62C,beta-lactamase_2500_62,TEM-1,beta-lactamase_2500,P62593,0.460407,NO,62,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.193,-5.228,4.035,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.361275,0.00264802,0.460407 kka2_1:1_A237Q,kka2_1:1_237,Kka2,kka2_1:1,P00552,0.460411,NO,237,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.12,-4.238,2.118,,0.068,H,A,0.46,-0.71,2.369,,92.05,HHA,-2.10433,0.520039,0.012257,0.460411 beta-lactamase_625_G142Y,beta-lactamase_625_142,TEM-1,beta-lactamase_625,P62593,0.460434,NO,142,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.707,-4.385,3.678,,0.034,,p,0.29,-0.64,1.35,,64.69,OOO,-0.834,0.213352,0.00060149,0.460434 Pab1_I130N,Pab1_130,Pab1,Pab1,P04147,0.460487,NO,130,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.212,-3.94,2.728,,,E,B,1.23,0.01,,,,HHB,-1.188,0.175299,0.000351112,0.460487 beta-lactamase_2500_T187F,beta-lactamase_2500_187,TEM-1,beta-lactamase_2500,P62593,0.460493,NO,187,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.401,-4.141,2.74,,0.007,H,A,0.22,-1.19,3.91,,67.48,PPH,-1.69633,0.361275,0.00491782,0.460493 kka2_1:4_G233D,kka2_1:4_233,Kka2,kka2_1:4,P00552,0.460611,NO,233,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.748,-2.136,1.388,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.168804,0.00232366,0.460611 beta-lactamase_2500_L160H,beta-lactamase_2500_160,TEM-1,beta-lactamase_2500,P62593,0.460714,NO,160,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.977,-4.948,3.971,,0.022,,B,0.55,-0.6,0.895,,44.41,BHA,-0.936,0.361275,0.00193775,0.460714 beta-lactamase_625_H110P,beta-lactamase_625_110,TEM-1,beta-lactamase_625,P62593,0.460718,NO,110,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-1.706,-2.996,1.29,,0.341,G,a,0.17,1.08,31.31,31.31,64.69,BBH,-1.73333,0.213352,0.00441499,0.460718 beta-lactamase_2500_V214P,beta-lactamase_2500_214,TEM-1,beta-lactamase_2500,P62593,0.460752,NO,214,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.299,-3.919,2.62,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.361275,0.00628442,0.460752 kka2_1:8_A117G,kka2_1:8_117,Kka2,kka2_1:8,P00552,0.460864,NO,117,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.828,-3.044,2.216,,,H,A,1.04,-0.78,0.755,,45.83,HHA,-1.79333,0.100394,0.00282984,0.460864 kka2_1:8_A117G,kka2_1:8_117,Kka2,kka2_1:8,P00552,0.460864,NO,117,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.828,-3.044,2.216,,,H,A,1.04,-0.78,0.755,,45.83,HHA,-1.79333,0.100394,0.00282984,0.460864 kka2_1:1_G43E,kka2_1:1_43,Kka2,kka2_1:1,P00552,0.460876,NO,43,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.587,-2.715,1.128,,0.862,T,l,0.75,-0.67,2.247,,63.26,POB,-2.18533,0.520039,0.0071925,0.460876 kka2_1:4_D208T,kka2_1:4_208,Kka2,kka2_1:4,P00552,0.46089,NO,208,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.708,-3.45,2.742,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.168804,0.00212588,0.46089 beta-lactamase_2500_L100T,beta-lactamase_2500_100,TEM-1,beta-lactamase_2500,P62593,0.460948,NO,100,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.218,-3.502,2.284,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.361275,0.00413885,0.460948 beta-lactamase_2500_L197Y,beta-lactamase_2500_197,TEM-1,beta-lactamase_2500,P62593,0.460976,NO,197,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.853,-3.986,3.133,,0.007,S,B,0.55,0.33,2.421,,60.14,HHP,-1.833,0.361275,0.00144602,0.460976 kka2_1:8_L170T,kka2_1:8_170,Kka2,kka2_1:8,P00552,0.461034,NO,170,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.28,-3.474,2.194,,0.029,H,A,1.59,0.11,1.453,,62.5,AHH,-1.534,0.100394,0.00730791,0.461034 kka2_1:8_L170T,kka2_1:8_170,Kka2,kka2_1:8,P00552,0.461034,NO,170,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.28,-3.474,2.194,,0.029,H,A,1.59,0.11,1.453,,62.5,AHH,-1.534,0.100394,0.00730791,0.461034 kka2_1:2_G164Y,kka2_1:2_164,Kka2,kka2_1:2,P00552,0.461038,NO,164,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.869,-4.442,3.573,,0.862,T,l,0.75,1.45,1.539,,64.39,POH,-1.828,0.295029,0.00442091,0.461038 beta-lactamase_625_T178N,beta-lactamase_625_178,TEM-1,beta-lactamase_625,P62593,0.461049,NO,178,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-0.791,-3.448,2.657,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.213352,0.000684366,0.461049 kka2_1:2_L158H,kka2_1:2_158,Kka2,kka2_1:2,P00552,0.461061,NO,158,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.947,-4.683,2.736,,0.095,,B,1.59,0.77,7.588,,63.64,AHA,-1.25333,0.295029,0.00529068,0.461061 beta-lactamase_M115H,beta-lactamase_115,TEM-1,beta-lactamase,P62593,0.461086,NO,115,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.389,-4.759,3.37,4.89743,0.019,E,B,1.3,0.08,1.236,,69.58,OHP,-1.25433,0.221079,0.0034337,0.461086 beta-lactamase_39_G43Y,beta-lactamase_39_43,TEM-1,beta-lactamase_39,P62593,0.461093,NO,43,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.62,-4.387,3.767,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.0495842,0.00120151,0.461093 kka2_1:8_L158G,kka2_1:8_158,Kka2,kka2_1:8,P00552,0.461203,NO,158,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.947,-3.704,1.757,,0.095,.,B,0.55,0.77,1.607,,63.64,AHA,-1.25333,0.100394,0.00529068,0.461203 kka2_1:8_L158G,kka2_1:8_158,Kka2,kka2_1:8,P00552,0.461203,NO,158,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.947,-3.704,1.757,,0.095,.,B,0.55,0.77,1.607,,63.64,AHA,-1.25333,0.100394,0.00529068,0.461203 kka2_1:1_A229K,kka2_1:1_229,Kka2,kka2_1:1,P00552,0.461219,NO,229,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.739,-3.497,1.758,,0.32,H,A,0.46,-0.7,6.549,,63.64,HHA,-1.851,0.520039,0.00942138,0.461219 beta-lactamase_625_S104R,beta-lactamase_625_104,TEM-1,beta-lactamase_625,P62593,0.46132,NO,104,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.015,-3.804,2.789,,0.04,,b,0.27,0.57,1.76,,63.29,HPO,-1.05267,0.213352,0.00218083,0.46132 beta-lactamase_2500_R159A,beta-lactamase_2500_159,TEM-1,beta-lactamase_2500,P62593,0.461366,NO,159,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-0.94,-3.127,2.187,,0.316,,B,1.2,-0.55,2.341,,64.34,PBH,-1.011,0.361275,0.00108472,0.461366 beta-lactamase_2500_R202W,beta-lactamase_2500_202,TEM-1,beta-lactamase_2500,P62593,0.461376,NO,202,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.292,-5.342,4.05,,0.188,H,A,1.2,0.62,3.734,,77.62,PBP,-1.54767,0.361275,0.00321899,0.461376 beta-lactamase_625_L137W,beta-lactamase_625_137,TEM-1,beta-lactamase_625,P62593,0.461376,NO,137,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.03,-5.164,4.134,,,H,A,0.55,-0.38,1.5,,42.31,HHP,-1.58933,0.213352,0.00278599,0.461376 beta-lactamase_39_A185K,beta-lactamase_39_185,TEM-1,beta-lactamase_39,P62593,0.461446,NO,185,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.406,-3.666,2.26,,,H,A,0.46,-1.02,2.68,,65.03,HHP,-1.84033,0.0495842,0.00467449,0.461446 kka2_1:2_F256A,kka2_1:2_256,Kka2,kka2_1:2,P00552,0.461448,NO,256,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.49,-3.439,1.949,,,H,A,0.58,-0.78,1.653,,53.03,HHH,-1.423,0.295029,0.0132841,0.461448 kka2_1:8_R140D,kka2_1:8_140,Kka2,kka2_1:8,P00552,0.461457,NO,140,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.351,-3.692,2.341,,0.12,H,A,0.16,0.2,2.874,,53.03,BBH,-1.885,0.100394,0.00430167,0.461457 kka2_1:8_R140D,kka2_1:8_140,Kka2,kka2_1:8,P00552,0.461457,NO,140,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.351,-3.692,2.341,,0.12,H,A,0.16,0.2,2.874,,53.03,BBH,-1.885,0.100394,0.00430167,0.461457 kka2_1:2_W69P,kka2_1:2_69,Kka2,kka2_1:2,P00552,0.461518,NO,69,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-0.859,-4.356,3.497,,0.164,H,A,0.47,0.15,5.074,,38.64,PHH,-1.49967,0.295029,0.0012874,0.461518 kka2_1:2_A222V,kka2_1:2_222,Kka2,kka2_1:2,P00552,0.461582,NO,222,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.725,-3.107,2.382,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.295029,0.00207657,0.461582 kka2_1:8_L158D,kka2_1:8_158,Kka2,kka2_1:8,P00552,0.461627,NO,158,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.947,-4.014,2.067,,0.095,.,B,0.55,0.77,1.607,,63.64,AHA,-1.25333,0.100394,0.00529068,0.461627 kka2_1:8_L158D,kka2_1:8_158,Kka2,kka2_1:8,P00552,0.461627,NO,158,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.947,-4.014,2.067,,0.095,.,B,0.55,0.77,1.607,,63.64,AHA,-1.25333,0.100394,0.00529068,0.461627 beta-lactamase_2500_S51C,beta-lactamase_2500_51,TEM-1,beta-lactamase_2500,P62593,0.461734,NO,51,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.526,-4.878,3.352,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.361275,0.00504821,0.461734 beta-lactamase_625_L248Y,beta-lactamase_625_248,TEM-1,beta-lactamase_625,P62593,0.461772,NO,248,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.213352,0.00428493,0.461772 kka2_1:1_P128I,kka2_1:1_128,Kka2,kka2_1:1,P00552,0.461804,NO,128,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.922,-1.808,-0.114,,0.316,G,A,0.52,0.4,2.178,,56.06,AOH,-1.64733,0.520039,0.00774689,0.461804 kka2_1:2_V198R,kka2_1:2_198,Kka2,kka2_1:2,P00552,0.461962,NO,198,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.719,-3.986,2.267,,0.05,E,B,1.48,-0.95,1.074,,56.06,HHA,-1.88667,0.295029,0.00835002,0.461962 kka2_1:2_D62L,kka2_1:2_62,Kka2,kka2_1:2,P00552,0.462419,NO,62,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.591,-3.008,1.417,,0.262,H,A,0.75,0.08,10.048,10.048,64.39,PAA,-1.77833,0.295029,0.00744243,0.462419 kka2_1:1_A56R,kka2_1:1_56,Kka2,kka2_1:1,P00552,0.462496,NO,56,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.083,-3.254,1.171,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.520039,0.00717715,0.462496 beta-lactamase_2500_I277C,beta-lactamase_2500_277,TEM-1,beta-lactamase_2500,P62593,0.462499,NO,277,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.361275,0.0169305,0.462499 kka2_1:1_G245Q,kka2_1:1_245,Kka2,kka2_1:1,P00552,0.462552,NO,245,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.812,-4.042,3.23,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.520039,0.00683899,0.462552 beta-lactamase_2500_D231Q,beta-lactamase_2500_231,TEM-1,beta-lactamase_2500,P62593,0.462562,NO,231,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.816,-3.637,2.821,,,E,B,0.75,-1.06,0.319,,65.38,HAB,-0.994,0.361275,0.00107395,0.462562 kka2_1:1_A191T,kka2_1:1_191,Kka2,kka2_1:1,P00552,0.462564,NO,191,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.831,-3.288,2.457,,,.,b,0.46,-0.94,0.53,,50,AHO,-0.868667,0.520039,0.00338807,0.462564 kka2_1:1_P98L,kka2_1:1_98,Kka2,kka2_1:1,P00552,0.462676,NO,98,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.526,-3.014,1.488,,0.391,S,B,0.52,-0.65,1.521,,63.26,HOO,-1.19167,0.520039,0.00622754,0.462676 beta-lactamase_L282Y,beta-lactamase_282,TEM-1,beta-lactamase,P62593,0.462715,NO,282,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.586,-3.988,2.402,5.16743,0.007,H,A,1.07,0.34,31.31,31.31,63.99,PHH,-1.82367,0.221079,0.0449821,0.462715 kka2_1:2_D159M,kka2_1:2_159,Kka2,kka2_1:2,P00552,0.462777,NO,159,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.82,-4.992,4.172,,0.28,.,B,0.75,1.25,0.899,,48.11,HAA,-1.48333,0.295029,0.0030485,0.462777 beta-lactamase_P65F,beta-lactamase_65,TEM-1,beta-lactamase,P62593,0.462786,NO,65,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.894,-4.306,3.412,5.59094,0.098,E,B,0.23,-0.62,0.623,,40.56,HOH,-1.03233,0.221079,0.00152776,0.462786 beta-lactamase_39_Y262G,beta-lactamase_39_262,TEM-1,beta-lactamase_39,P62593,0.462801,NO,262,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.0495842,0.00853516,0.462801 beta-lactamase_39_E164K,beta-lactamase_39_164,TEM-1,beta-lactamase_39,P62593,0.462842,NO,164,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-0.948,-2.425,1.477,,0.011,T,B,1.04,-0.4,0.664,,64.69,HAO,-1.388,0.0495842,0.00137286,0.462842 beta-lactamase_625_M66S,beta-lactamase_625_66,TEM-1,beta-lactamase_625,P62593,0.46286,NO,66,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.362,-3.571,2.209,,0.013,,A,0.55,-0.7,1.659,,73.08,OHH,-1.49567,0.213352,0.00412876,0.46286 kka2_1:1_N195T,kka2_1:1_195,Kka2,kka2_1:1,P00552,0.462904,NO,195,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-0.836,-3.268,2.432,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.520039,0.00276134,0.462904 beta-lactamase_2500_L89Q,beta-lactamase_2500_89,TEM-1,beta-lactamase_2500,P62593,0.462923,NO,89,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.096,-4.086,2.99,,0.168,T,A,0.55,0.63,2.066,,64.34,PHO,-1.75767,0.361275,0.00207068,0.462923 kka2_1:4_V185I,kka2_1:4_185,Kka2,kka2_1:4,P00552,0.462927,NO,185,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.045,-2.468,1.423,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.168804,0.00367031,0.462927 kka2_1:2_K112L,kka2_1:2_112,Kka2,kka2_1:2,P00552,0.462965,NO,112,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-2.491,-2.229,-0.262,,0.076,H,A,2.34,-1.37,23.433,23.433,56.06,ABH,-2.00133,0.295029,0.00645389,0.462965 kka2_1:4_L126R,kka2_1:4_126,Kka2,kka2_1:4,P00552,0.462968,NO,126,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.246,-4.098,2.852,,0.285,S,B,0.55,0.12,0.302,,51.89,PHA,-1.744,0.168804,0.0066485,0.462968 kka2_1:8_R147P,kka2_1:8_147,Kka2,kka2_1:8,P00552,0.462979,NO,147,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.123,-3.991,2.868,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.100394,0.00549168,0.462979 kka2_1:8_R147P,kka2_1:8_147,Kka2,kka2_1:8,P00552,0.462979,NO,147,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.123,-3.991,2.868,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.100394,0.00549168,0.462979 beta-lactamase_625_I229F,beta-lactamase_625_229,TEM-1,beta-lactamase_625,P62593,0.463042,NO,229,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.267,-3.792,2.525,,0.083,E,B,0.48,-0.76,1.69,,50,HHH,-1.58767,0.213352,0.00477249,0.463042 kka2_1:2_A34P,kka2_1:2_34,Kka2,kka2_1:2,P00552,0.463054,NO,34,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.928,-3.715,2.787,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.295029,0.00343484,0.463054 kka2_1:1_D154R,kka2_1:1_154,Kka2,kka2_1:1,P00552,0.46306,NO,154,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.876,-3.899,3.023,,0.457,.,b,0.75,1.48,0.658,,52.65,HAP,-1.52467,0.520039,0.00292633,0.46306 kka2_1:2_A65P,kka2_1:2_65,Kka2,kka2_1:2,P00552,0.463082,NO,65,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.744,-4.019,2.275,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.295029,0.00709258,0.463082 beta-lactamase_2500_G76I,beta-lactamase_2500_76,TEM-1,beta-lactamase_2500,P62593,0.463117,NO,76,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.189,-3.948,2.759,,,H,A,0.29,-0.67,1.012,,67.83,OOH,-1.22267,0.361275,0.00476637,0.463117 beta-lactamase_625_L100G,beta-lactamase_625_100,TEM-1,beta-lactamase_625,P62593,0.463122,NO,100,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.218,-3.854,2.636,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.213352,0.00413885,0.463122 kka2_1:2_G205L,kka2_1:2_205,Kka2,kka2_1:2,P00552,0.463161,NO,205,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.596,-3.836,3.24,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.295029,0.00221855,0.463161 beta-lactamase_V78W,beta-lactamase_78,TEM-1,beta-lactamase,P62593,0.463181,NO,78,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.459,-5.345,3.886,4.79197,,H,A,0.96,-0.47,1.132,,63.64,HHH,-1.17833,0.221079,0.00492501,0.463181 beta-lactamase_625_I206D,beta-lactamase_625_206,TEM-1,beta-lactamase_625,P62593,0.463204,NO,206,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-2.429,-3.794,1.365,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.213352,0.00528934,0.463204 beta-lactamase_625_L219S,beta-lactamase_625_219,TEM-1,beta-lactamase_625,P62593,0.46322,NO,219,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.313,-3.686,2.373,,,I,A,0.55,-0.51,5.627,,74.48,HHB,-1.21533,0.213352,0.00664345,0.46322 kka2_1:1_D227A,kka2_1:1_227,Kka2,kka2_1:1,P00552,0.463265,NO,227,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.758,-2.851,1.093,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.520039,0.00745029,0.463265 kka2_1:1_S54C,kka2_1:1_54,Kka2,kka2_1:1,P00552,0.463331,NO,54,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.471,-4.966,2.495,,0.408,S,b,0.27,1.01,6.085,,71.59,HPO,-2.259,0.520039,0.00782867,0.463331 kka2_1:1_F240S,kka2_1:1_240,Kka2,kka2_1:1,P00552,0.463391,NO,240,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-0.911,-3.673,2.762,,,H,A,1.62,-1.21,5.798,,50.38,BHH,-1.67267,0.520039,0.00552543,0.463391 kka2_1:2_A137D,kka2_1:2_137,Kka2,kka2_1:2,P00552,0.463415,NO,137,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.156,-4.088,1.932,,0.029,H,A,0.46,0.34,1.323,,63.26,PHB,-2.559,0.295029,0.00515054,0.463415 kka2_1:2_A34G,kka2_1:2_34,Kka2,kka2_1:2,P00552,0.463421,NO,34,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.928,-2.969,2.041,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.295029,0.00343484,0.463421 beta-lactamase_625_P181G,beta-lactamase_625_181,TEM-1,beta-lactamase_625,P62593,0.463432,NO,181,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.813,-3.321,2.508,,,H,A,0.52,-1.14,1.797,,61.54,HOH,-1.795,0.213352,0.000703122,0.463432 kka2_1:4_G205Q,kka2_1:4_205,Kka2,kka2_1:4,P00552,0.463452,NO,205,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.596,-4.153,3.557,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.168804,0.00221855,0.463452 kka2_1:2_H162D,kka2_1:2_162,Kka2,kka2_1:2,P00552,0.463476,NO,162,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-2.319,-3.685,1.366,,0.071,G,A,0.17,1.01,3.187,,64.39,ABP,-2.02067,0.295029,0.00616145,0.463476 beta-lactamase_39_D155W,beta-lactamase_39_155,TEM-1,beta-lactamase_39,P62593,0.463479,NO,155,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.889,-5.571,4.682,,0.049,,B,0.75,-0.9,3.208,,64.69,OAB,-1.62267,0.0495842,0.00135315,0.463479 kka2_1:8_I221F,kka2_1:8_221,Kka2,kka2_1:8,P00552,0.463485,NO,221,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.739,-3.76,2.021,,,H,A,1.52,-1.15,1.599,,71.59,AHH,-1.08367,0.100394,0.00945908,0.463485 kka2_1:8_I221F,kka2_1:8_221,Kka2,kka2_1:8,P00552,0.463485,NO,221,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.739,-3.76,2.021,,,H,A,1.52,-1.15,1.599,,71.59,AHH,-1.08367,0.100394,0.00945908,0.463485 kka2_1:2_F203V,kka2_1:2_203,Kka2,kka2_1:2,P00552,0.463568,NO,203,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-0.911,-3.287,2.376,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.295029,0.00318738,0.463568 kka2_1:1_R38E,kka2_1:1_38,Kka2,kka2_1:1,P00552,0.463589,NO,38,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.207,-3.518,2.311,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.520039,0.00372499,0.463589 kka2_1:1_R38Y,kka2_1:1_38,Kka2,kka2_1:1,P00552,0.463589,NO,38,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.207,-4.179,2.972,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.520039,0.00372499,0.463589 kka2_1:2_G30Y,kka2_1:2_30,Kka2,kka2_1:2,P00552,0.463644,NO,30,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.596,-4.416,3.82,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.295029,0.00159208,0.463644 beta-lactamase_156_M115D,beta-lactamase_156_115,TEM-1,beta-lactamase_156,P62593,0.463677,NO,115,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.389,-4.023,2.634,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.111618,0.0034337,0.463677 kka2_1:4_W91Q,kka2_1:4_91,Kka2,kka2_1:4,P00552,0.463764,NO,91,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-1.178,-4.104,2.926,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.168804,0.00358653,0.463764 kka2_1:1_L243A,kka2_1:1_243,Kka2,kka2_1:1,P00552,0.463925,NO,243,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-2.651,-2.102,-0.549,,0.277,H,A,0.55,-0.67,4.334,,92.05,HHH,-2.03767,0.520039,0.00884927,0.463925 kka2_1:8_D208E,kka2_1:8_208,Kka2,kka2_1:8,P00552,0.463989,NO,208,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.708,-2.793,2.085,,0.36,,l,0.29,-1.01,,,,HAO,-0.929667,0.100394,0.00212588,0.463989 kka2_1:8_D208E,kka2_1:8_208,Kka2,kka2_1:8,P00552,0.463989,NO,208,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.708,-2.793,2.085,,0.36,,l,0.29,-1.01,,,,HAO,-0.929667,0.100394,0.00212588,0.463989 kka2_1:1_A166N,kka2_1:1_166,Kka2,kka2_1:1,P00552,0.463991,NO,166,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.407,-3.048,0.641,,0.534,.,B,0.46,1.03,1.147,,71.59,HHO,-2.421,0.520039,0.00799912,0.463991 kka2_1:4_R258A,kka2_1:4_258,Kka2,kka2_1:4,P00552,0.463991,NO,258,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.626,-3.206,1.58,,0.316,H,A,1.2,-0.85,2.655,,53.03,HBH,-1.25933,0.168804,0.00983174,0.463991 kka2_1:1_V75I,kka2_1:1_75,Kka2,kka2_1:1,P00552,0.464022,NO,75,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-2.06,-1.939,-0.121,,0.042,.,B,0.44,-0.2,2.815,,71.59,OHO,-1.563,0.520039,0.00693733,0.464022 kka2_1:4_A222E,kka2_1:4_222,Kka2,kka2_1:4,P00552,0.464025,NO,222,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.725,-3.468,2.743,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.168804,0.00207657,0.464025 beta-lactamase_625_L219N,beta-lactamase_625_219,TEM-1,beta-lactamase_625,P62593,0.464032,NO,219,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.313,-4.217,2.904,,,I,A,0.55,-0.51,5.627,,74.48,HHB,-1.21533,0.213352,0.00664345,0.464032 kka2_1:1_E86K,kka2_1:1_86,Kka2,kka2_1:1,P00552,0.464061,NO,86,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.86,-3.566,1.706,,0.369,.,B,1.04,1.92,18.506,18.506,63.26,PAH,-1.98067,0.520039,0.00642858,0.464061 kka2_1:1_T125Y,kka2_1:1_125,Kka2,kka2_1:1,P00552,0.4641,NO,125,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.622,-4.422,1.8,,0.791,T,A,0.22,0.33,1.972,,92.05,BPH,-1.56933,0.520039,0.00821755,0.4641 kka2_1:1_T146S,kka2_1:1_146,Kka2,kka2_1:1,P00552,0.464187,NO,146,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.978,-2.727,-0.251,,0.281,H,A,0.82,0.78,2.105,,92.05,BPB,-1.96833,0.520039,0.00606474,0.464187 beta-lactamase_0_T107H,beta-lactamase_0_107,TEM-1,beta-lactamase_0,P62593,0.464208,NO,107,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.117,-4.67,3.553,,,G,A,0.22,-0.06,3.73,,67.83,HPA,-1.265,0.0500837,0.00239347,0.464208 kka2_1:8_G210M,kka2_1:8_210,Kka2,kka2_1:8,P00552,0.464255,NO,210,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.095,-4.836,3.741,,0.103,T,A,0.75,-0.62,2.687,,50,OOB,-0.966667,0.100394,0.00598378,0.464255 kka2_1:8_G210M,kka2_1:8_210,Kka2,kka2_1:8,P00552,0.464255,NO,210,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.095,-4.836,3.741,,0.103,T,A,0.75,-0.62,2.687,,50,OOB,-0.966667,0.100394,0.00598378,0.464255 beta-lactamase_0_M180N,beta-lactamase_0_180,TEM-1,beta-lactamase_0,P62593,0.464258,NO,180,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-2.795,-3.603,0.808,,0.242,,B,0.55,-0.94,2.892,,77.62,PHO,-1.56433,0.0500837,0.00552048,0.464258 kka2_1:4_D101Y,kka2_1:4_101,Kka2,kka2_1:4,P00552,0.464274,NO,101,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.028,-4.399,3.371,,0.213,E,B,0.75,-1.24,8.707,,63.64,PAH,-1.534,0.168804,0.00423361,0.464274 kka2_1:2_Q100Y,kka2_1:2_100,Kka2,kka2_1:2,P00552,0.464323,NO,100,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.77,-4.334,1.564,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.295029,0.0066405,0.464323 beta-lactamase_N272R,beta-lactamase_272,TEM-1,beta-lactamase,P62593,0.464344,NO,272,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-1.127,-2.715,1.588,5.37826,0.081,H,A,0.09,-0.97,1.468,,63.64,BPB,-1.56333,0.221079,0.00545371,0.464344 beta-lactamase_V42S,beta-lactamase_42,TEM-1,beta-lactamase,P62593,0.464344,NO,42,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.564,-3.633,2.069,5.27904,0.017,E,B,1.64,-0.51,2.024,,63.99,BHO,-1.042,0.221079,0.00404515,0.464344 kka2_1:1_G43K,kka2_1:1_43,Kka2,kka2_1:1,P00552,0.464441,NO,43,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.587,-3.606,2.019,,0.862,T,l,0.75,-0.67,2.247,,63.26,POB,-2.18533,0.520039,0.0071925,0.464441 beta-lactamase_156_L191K,beta-lactamase_156_191,TEM-1,beta-lactamase_156,P62593,0.46448,NO,191,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.087,-3.741,2.654,,,H,A,0.55,0.09,1.372,,63.29,BHH,-1.445,0.111618,0.00263549,0.46448 kka2_1:1_L174S,kka2_1:1_174,Kka2,kka2_1:1,P00552,0.464536,NO,174,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.952,-3.62,2.668,,,H,A,0.55,-0.31,13.276,13.276,51.89,BHB,-2.08533,0.520039,0.00438501,0.464536 kka2_1:4_P76F,kka2_1:4_76,Kka2,kka2_1:4,P00552,0.464553,NO,76,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.449,-4.424,2.975,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.168804,0.00625685,0.464553 beta-lactamase_N130A,beta-lactamase_130,TEM-1,beta-lactamase,P62593,0.464611,NO,130,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-0.798,-3.303,2.505,5.26686,0.069,H,A,1.08,-0.74,,,,APP,-0.980667,0.221079,0.000683376,0.464611 beta-lactamase_N168Y,beta-lactamase_168,TEM-1,beta-lactamase,P62593,0.46464,NO,168,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-1.029,-4.205,3.176,5.42128,0.113,G,A,0.09,-0.4,1.211,,44.41,HPA,-1.13233,0.221079,0.00288667,0.46464 kka2_1:2_G189Y,kka2_1:2_189,Kka2,kka2_1:2,P00552,0.464642,NO,189,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.596,-4.416,3.82,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.295029,0.00253688,0.464642 kka2_1:2_L170C,kka2_1:2_170,Kka2,kka2_1:2,P00552,0.464656,NO,170,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.28,-4.755,3.475,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.295029,0.00730791,0.464656 beta-lactamase_2500_L137C,beta-lactamase_2500_137,TEM-1,beta-lactamase_2500,P62593,0.464661,NO,137,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.03,-4.702,3.672,,,H,A,0.55,-0.38,0.769,,42.31,HHP,-1.58933,0.361275,0.00278599,0.464661 kka2_1:8_L212H,kka2_1:8_212,Kka2,kka2_1:8,P00552,0.464666,NO,212,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.904,-4.956,4.052,,,,B,1.59,-0.78,1.708,,42.42,BHO,-0.799667,0.100394,0.0031426,0.464666 kka2_1:8_L212H,kka2_1:8_212,Kka2,kka2_1:8,P00552,0.464666,NO,212,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.904,-4.956,4.052,,,,B,1.59,-0.78,1.708,,42.42,BHO,-0.799667,0.100394,0.0031426,0.464666 kka2_1:8_L212Y,kka2_1:8_212,Kka2,kka2_1:8,P00552,0.464666,NO,212,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.904,-4.048,3.144,,,,B,1.59,-0.78,1.708,,42.42,BHO,-0.799667,0.100394,0.0031426,0.464666 kka2_1:8_L212Y,kka2_1:8_212,Kka2,kka2_1:8,P00552,0.464666,NO,212,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.904,-4.048,3.144,,,,B,1.59,-0.78,1.708,,42.42,BHO,-0.799667,0.100394,0.0031426,0.464666 kka2_1:4_E161Y,kka2_1:4_161,Kka2,kka2_1:4,P00552,0.464673,NO,161,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.581,-4.394,2.813,,0.829,G,A,1.52,2.24,1.612,,92.05,AAB,-1.861,0.168804,0.00760103,0.464673 beta-lactamase_2500_P250I,beta-lactamase_2500_250,TEM-1,beta-lactamase_2500,P62593,0.46468,NO,250,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.361275,0.00550899,0.46468 kka2_1:4_R140W,kka2_1:4_140,Kka2,kka2_1:4,P00552,0.464698,NO,140,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.351,-5.43,4.079,,0.12,H,A,1.2,0.2,2.561,,53.03,BBH,-1.885,0.168804,0.00430167,0.464698 Pab1_I128S,Pab1_128,Pab1,Pab1,P04147,0.464712,NO,128,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.345,-3.503,2.158,,0.008,E,B,1.68,-0.6,1.706,,78.68,PHH,-1.231,0.175299,0.00104192,0.464712 beta-lactamase_39_L136H,beta-lactamase_39_136,TEM-1,beta-lactamase_39,P62593,0.46473,NO,136,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.232,-4.999,3.767,,,H,A,0.55,-0.34,0.336,,48.95,HHH,-1.088,0.0495842,0.00442304,0.46473 beta-lactamase_0_M127W,beta-lactamase_0_127,TEM-1,beta-lactamase_0,P62593,0.464775,NO,127,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-2.251,-3.502,1.251,,0.312,S,A,0.55,0.32,9.35,9.35,72.73,PHP,-1.40433,0.0500837,0.00437927,0.464775 beta-lactamase_156_S57P,beta-lactamase_156_57,TEM-1,beta-lactamase_156,P62593,0.464869,NO,57,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.918,-3.952,2.034,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.111618,0.00492804,0.464869 beta-lactamase_F228D,beta-lactamase_228,TEM-1,beta-lactamase,P62593,0.464891,NO,228,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-2.342,-3.807,1.465,5.33448,0.154,E,B,1.1,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.221079,0.0046669,0.464891 beta-lactamase_625_S104Y,beta-lactamase_625_104,TEM-1,beta-lactamase_625,P62593,0.464904,NO,104,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.015,-4.223,3.208,,0.04,,b,0.27,0.57,1.76,,63.29,HPO,-1.05267,0.213352,0.00218083,0.464904 kka2_1:1_N200T,kka2_1:1_200,Kka2,kka2_1:1,P00552,0.464958,NO,200,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-2.446,-3.096,0.65,,0.756,T,L,0.61,-0.08,17.299,17.299,64.39,APO,-2.08,0.520039,0.00838549,0.464958 beta-lactamase_156_I261S,beta-lactamase_156_261,TEM-1,beta-lactamase_156,P62593,0.465054,NO,261,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.111618,0.0123091,0.465054 gb1_A249M,gb1_249,gb1,gb1,P06654,0.465093,NO,249,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.739,-4.29,2.551,,,,,,,0.252,,44.87,AHH,-1.67367,0.177985,0.00333585,0.465093 gb1_Y271G,gb1_271,gb1,gb1,P06654,0.465093,NO,271,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-1.181,-3.36,2.179,,,,,,,,,,PHA,-1.92933,0.177985,0.00236544,0.465093 beta-lactamase_2500_L89N,beta-lactamase_2500_89,TEM-1,beta-lactamase_2500,P62593,0.465094,NO,89,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.096,-4.11,3.014,,0.168,T,A,0.55,0.63,2.066,,64.34,PHO,-1.75767,0.361275,0.00207068,0.465094 kka2_1:2_L165G,kka2_1:2_165,Kka2,kka2_1:2,P00552,0.465154,NO,165,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-2.453,-3.006,0.553,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.295029,0.00801161,0.465154 kka2_1:4_V113L,kka2_1:4_113,Kka2,kka2_1:4,P00552,0.465279,NO,113,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.233,-2.374,1.141,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.168804,0.00650191,0.465279 kka2_1:8_D159V,kka2_1:8_159,Kka2,kka2_1:8,P00552,0.465332,NO,159,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.82,-3.816,2.996,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.100394,0.0030485,0.465332 kka2_1:8_D159V,kka2_1:8_159,Kka2,kka2_1:8,P00552,0.465332,NO,159,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.82,-3.816,2.996,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.100394,0.0030485,0.465332 kka2_1:1_A166V,kka2_1:1_166,Kka2,kka2_1:1,P00552,0.465381,NO,166,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.407,-3.015,0.608,,0.534,.,B,0.46,1.03,1.147,,71.59,HHO,-2.421,0.520039,0.00799912,0.465381 kka2_1:1_G88A,kka2_1:1_88,Kka2,kka2_1:1,P00552,0.465399,NO,88,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.689,-2.52,0.831,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.520039,0.00685559,0.465399 kka2_1:2_T130P,kka2_1:2_130,Kka2,kka2_1:2,P00552,0.465426,NO,130,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.392,-4.046,1.654,,0.561,G,A,0.22,0.77,0.5,,92.05,HPO,-1.62633,0.295029,0.00804204,0.465426 beta-lactamase_625_S104V,beta-lactamase_625_104,TEM-1,beta-lactamase_625,P62593,0.465457,NO,104,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.015,-3.487,2.472,,0.04,,b,0.27,0.57,1.76,,63.29,HPO,-1.05267,0.213352,0.00218083,0.465457 kka2_1:2_N58Y,kka2_1:2_58,Kka2,kka2_1:2,P00552,0.465516,NO,58,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-2.641,-4.48,1.839,,0.131,S,A,0.43,0.72,5.729,,71.59,HPA,-1.83033,0.295029,0.00793425,0.465516 kka2_1:4_C131R,kka2_1:4_131,Kka2,kka2_1:4,P00552,0.465538,NO,131,C,R,CR,Special,PositiveCharge,5.07,6.34148,1.27148,180,121,174,53,108.5,173.4,64.9,-0.831,-4.186,3.355,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.168804,0.00170814,0.465538 beta-lactamase_625_V72F,beta-lactamase_625_72,TEM-1,beta-lactamase_625,P62593,0.465712,NO,72,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.658,-3.023,1.365,,,H,A,0.44,-1.03,0.981,,65.73,BHH,-1.32167,0.213352,0.00501194,0.465712 beta-lactamase_2500_L188S,beta-lactamase_2500_188,TEM-1,beta-lactamase_2500,P62593,0.465751,NO,188,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.166,-3.587,2.421,,,H,A,0.55,-0.3,17.865,17.865,60.14,PHB,-1.47033,0.361275,0.00295687,0.465751 kka2_1:4_A119K,kka2_1:4_119,Kka2,kka2_1:4,P00552,0.46579,NO,119,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.073,-3.574,2.501,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.168804,0.00441074,0.46579 beta-lactamase_2500_V42T,beta-lactamase_2500_42,TEM-1,beta-lactamase_2500,P62593,0.465861,NO,42,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.564,-3.48,1.916,,0.017,E,B,0.44,-0.51,1.86,,63.99,BHO,-1.042,0.361275,0.00404515,0.465861 kka2_1:4_V214Y,kka2_1:4_214,Kka2,kka2_1:4,P00552,0.465866,NO,214,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.261,-4.127,2.866,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.168804,0.00692782,0.465866 kka2_1:2_D62N,kka2_1:2_62,Kka2,kka2_1:2,P00552,0.465878,NO,62,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.591,-2.947,1.356,,0.262,H,A,0.75,0.08,10.048,10.048,64.39,PAA,-1.77833,0.295029,0.00744243,0.465878 beta-lactamase_625_G240C,beta-lactamase_625_240,TEM-1,beta-lactamase_625,P62593,0.465922,NO,240,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.213352,0.00591201,0.465922 kka2_1:8_F240T,kka2_1:8_240,Kka2,kka2_1:8,P00552,0.46596,NO,240,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-0.911,-3.673,2.762,,,H,A,1.62,-1.21,0.697,,50.38,BHH,-1.67267,0.100394,0.00552543,0.46596 kka2_1:8_F240T,kka2_1:8_240,Kka2,kka2_1:8,P00552,0.46596,NO,240,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-0.911,-3.673,2.762,,,H,A,1.62,-1.21,0.697,,50.38,BHH,-1.67267,0.100394,0.00552543,0.46596 kka2_1:2_R239N,kka2_1:2_239,Kka2,kka2_1:2,P00552,0.466088,NO,239,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.949,-3.912,0.963,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.295029,0.00835326,0.466088 kka2_1:1_L260V,kka2_1:1_260,Kka2,kka2_1:1,P00552,0.466104,NO,260,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.741,-2.882,2.141,,0.022,H,A,0.55,-0.52,,,,HHA,-0.845667,0.520039,0.0233782,0.466104 beta-lactamase_156_V259W,beta-lactamase_156_259,TEM-1,beta-lactamase_156,P62593,0.46616,NO,259,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.111618,0.0070773,0.46616 kka2_1:8_G233D,kka2_1:8_233,Kka2,kka2_1:8,P00552,0.466168,NO,233,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.748,-2.136,1.388,,0.172,,b,0.75,-0.27,1.134,,49.24,HOO,-1.72067,0.100394,0.00232366,0.466168 kka2_1:8_G233D,kka2_1:8_233,Kka2,kka2_1:8,P00552,0.466168,NO,233,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.748,-2.136,1.388,,0.172,,b,0.75,-0.27,1.134,,49.24,HOO,-1.72067,0.100394,0.00232366,0.466168 beta-lactamase_156_Y44T,beta-lactamase_156_44,TEM-1,beta-lactamase_156,P62593,0.466182,NO,44,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-2.547,-2.836,0.289,,,E,B,0.21,-0.45,2.184,,73.78,OHH,-1.86267,0.111618,0.00426364,0.466182 kka2_1:2_T28F,kka2_1:2_28,Kka2,kka2_1:2,P00552,0.466218,NO,28,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.883,-4.355,2.472,,0.353,S,B,0.22,2.02,2.655,,63.64,PPH,-1.74467,0.295029,0.00743084,0.466218 beta-lactamase_625_R220L,beta-lactamase_625_220,TEM-1,beta-lactamase_625,P62593,0.46633,NO,220,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-0.942,-3.356,2.414,,0.295,I,A,1.2,-0.76,5.086,,74.48,HBP,-1.33633,0.213352,0.00232421,0.46633 beta-lactamase_625_L135N,beta-lactamase_625_135,TEM-1,beta-lactamase_625,P62593,0.466387,NO,135,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.002,-4.152,3.15,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.213352,0.00244423,0.466387 beta-lactamase_625_D174V,beta-lactamase_625_174,TEM-1,beta-lactamase_625,P62593,0.466392,NO,174,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.738,-3.754,3.016,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.213352,0.00125633,0.466392 kka2_1:8_A222I,kka2_1:8_222,Kka2,kka2_1:8,P00552,0.466415,NO,222,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.725,-3.589,2.864,,,H,A,1.04,-1.21,,,,HHH,-1.10833,0.100394,0.00207657,0.466415 kka2_1:8_A222I,kka2_1:8_222,Kka2,kka2_1:8,P00552,0.466415,NO,222,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.725,-3.589,2.864,,,H,A,1.04,-1.21,,,,HHH,-1.10833,0.100394,0.00207657,0.466415 beta-lactamase_625_R59M,beta-lactamase_625_59,TEM-1,beta-lactamase_625,P62593,0.466554,NO,59,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.345,-4.605,3.26,,0.329,S,L,1.2,-0.09,2.995,,73.08,HBO,-2.24267,0.213352,0.00318082,0.466554 kka2_1:1_E231R,kka2_1:1_231,Kka2,kka2_1:1,P00552,0.466555,NO,231,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.002,-3.767,1.765,,0.503,H,A,1.04,-0.23,25.629,25.629,63.26,AAH,-2.06267,0.520039,0.00732383,0.466555 beta-lactamase_2500_L135H,beta-lactamase_2500_135,TEM-1,beta-lactamase_2500,P62593,0.466645,NO,135,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.002,-4.934,3.932,,0.117,H,A,0.55,-0.58,0.795,,43.71,PHH,-1.03767,0.361275,0.00244423,0.466645 kka2_1:2_Q26G,kka2_1:2_26,Kka2,kka2_1:2,P00552,0.466676,NO,26,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.18,-2.702,0.522,,0.448,E,B,0.4,0.44,5.022,,92.05,HPP,-2.11167,0.295029,0.00708962,0.466676 kka2_1:8_W69H,kka2_1:8_69,Kka2,kka2_1:8,P00552,0.466735,NO,69,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-0.859,-4.594,3.735,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.100394,0.0012874,0.466735 kka2_1:8_W69H,kka2_1:8_69,Kka2,kka2_1:8,P00552,0.466735,NO,69,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-0.859,-4.594,3.735,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.100394,0.0012874,0.466735 beta-lactamase_156_G249C,beta-lactamase_156_249,TEM-1,beta-lactamase_156,P62593,0.466814,NO,249,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.111618,0.00220169,0.466814 kka2_1:8_L223S,kka2_1:8_223,Kka2,kka2_1:8,P00552,0.466848,NO,223,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.861,-3.684,2.823,,,H,A,1.59,-1.24,1.017,,50,HHH,-0.854333,0.100394,0.00253574,0.466848 kka2_1:8_L223S,kka2_1:8_223,Kka2,kka2_1:8,P00552,0.466848,NO,223,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.861,-3.684,2.823,,,H,A,1.59,-1.24,1.017,,50,HHH,-0.854333,0.100394,0.00253574,0.466848 kka2_1:1_V113L,kka2_1:1_113,Kka2,kka2_1:1,P00552,0.466916,NO,113,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.233,-2.374,1.141,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.520039,0.00650191,0.466916 beta-lactamase_I278T,beta-lactamase_278,TEM-1,beta-lactamase,P62593,0.466926,NO,278,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.348,-2.688,1.34,5.35127,0.015,H,A,0.77,-0.85,2.718,,63.29,AHO,-1.41833,0.221079,0.0310297,0.466926 kka2_1:8_R217Q,kka2_1:8_217,Kka2,kka2_1:8,P00552,0.467002,NO,217,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.158,-2.901,1.743,,0.252,T,A,0.16,-0.59,1.151,,52.27,ABH,-1.127,0.100394,0.0047191,0.467002 kka2_1:8_R217Q,kka2_1:8_217,Kka2,kka2_1:8,P00552,0.467002,NO,217,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.158,-2.901,1.743,,0.252,T,A,0.16,-0.59,1.151,,52.27,ABH,-1.127,0.100394,0.0047191,0.467002 kka2_1:8_A224Y,kka2_1:8_224,Kka2,kka2_1:8,P00552,0.467088,NO,224,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.977,-4.257,3.28,,,H,A,0.46,-1.26,0.357,,63.64,HHP,-1.41033,0.100394,0.00352047,0.467088 kka2_1:8_A224Y,kka2_1:8_224,Kka2,kka2_1:8,P00552,0.467088,NO,224,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.977,-4.257,3.28,,,H,A,0.46,-1.26,0.357,,63.64,HHP,-1.41033,0.100394,0.00352047,0.467088 beta-lactamase_2500_L248F,beta-lactamase_2500_248,TEM-1,beta-lactamase_2500,P62593,0.467113,NO,248,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.361275,0.00428493,0.467113 beta-lactamase_625_G114V,beta-lactamase_625_114,TEM-1,beta-lactamase_625,P62593,0.467132,NO,114,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.094,-3.65,2.556,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.213352,0.00224919,0.467132 kka2_1:2_G205A,kka2_1:2_205,Kka2,kka2_1:2,P00552,0.467244,NO,205,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.596,-2.881,2.285,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.295029,0.00221855,0.467244 kka2_1:1_R173H,kka2_1:1_173,Kka2,kka2_1:1,P00552,0.467246,NO,173,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.407,-4.589,2.182,,0.308,H,A,0.16,-0.13,14.756,14.756,65.53,HBH,-1.70533,0.520039,0.00784999,0.467246 beta-lactamase_2500_F70N,beta-lactamase_2500_70,TEM-1,beta-lactamase_2500,P62593,0.4673,NO,70,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.169,-4.034,2.865,,,H,A,0.58,-1.34,1.918,,63.99,PHB,-0.980667,0.361275,0.00193499,0.4673 kka2_1:2_E59F,kka2_1:2_59,Kka2,kka2_1:2,P00552,0.467334,NO,59,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-0.952,-4.364,3.412,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.295029,0.00280355,0.467334 beta-lactamase_2500_L137S,beta-lactamase_2500_137,TEM-1,beta-lactamase_2500,P62593,0.467393,NO,137,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.03,-3.64,2.61,,,H,A,0.55,-0.38,0.769,,42.31,HHP,-1.58933,0.361275,0.00278599,0.467393 kka2_1:2_E262V,kka2_1:2_262,Kka2,kka2_1:2,P00552,0.467421,NO,262,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-0.829,-3.58,2.751,,0.059,G,A,1.04,-0.18,2.383,,42.42,AAH,-0.816,0.295029,0.0191586,0.467421 beta-lactamase_2500_G76M,beta-lactamase_2500_76,TEM-1,beta-lactamase_2500,P62593,0.467449,NO,76,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.189,-4.767,3.578,,,H,A,0.29,-0.67,1.012,,67.83,OOH,-1.22267,0.361275,0.00476637,0.467449 kka2_1:2_D118I,kka2_1:2_118,Kka2,kka2_1:2,P00552,0.467455,NO,118,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.07,-3.314,1.244,,0.61,H,A,0.75,-0.05,2.237,,64.39,HAH,-1.32367,0.295029,0.0067852,0.467455 kka2_1:1_P45E,kka2_1:1_45,Kka2,kka2_1:1,P00552,0.467463,NO,45,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.774,-2.616,0.842,,0.669,.,B,0.52,-0.76,4.882,,71.59,BOH,-2.152,0.520039,0.00590481,0.467463 beta-lactamase_L219Y,beta-lactamase_219,TEM-1,beta-lactamase,P62593,0.46747,NO,219,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.313,-3.958,2.645,5.74153,,I,A,0.84,-0.51,2.321,,74.48,HHB,-1.21533,0.221079,0.00664345,0.46747 kka2_1:1_D238C,kka2_1:1_238,Kka2,kka2_1:1,P00552,0.467475,NO,238,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.83,-5.149,2.319,,0.604,H,A,0.75,-0.33,11.329,11.329,92.05,HAB,-2.633,0.520039,0.0113863,0.467475 kka2_1:4_I196W,kka2_1:4_196,Kka2,kka2_1:4,P00552,0.4675,NO,196,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-2.115,-4.933,2.818,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.168804,0.0107273,0.4675 kka2_1:1_Q252F,kka2_1:1_252,Kka2,kka2_1:1,P00552,0.467572,NO,252,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.63,-4.468,1.838,,0.906,H,A,0.64,0.35,1.369,,92.05,PPB,-2.20733,0.520039,0.0121001,0.467572 kka2_1:2_A176W,kka2_1:2_176,Kka2,kka2_1:2,P00552,0.467617,NO,176,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.621,-5.554,3.933,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.295029,0.0083587,0.467617 beta-lactamase_156_V78G,beta-lactamase_156_78,TEM-1,beta-lactamase_156,P62593,0.467655,NO,78,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.459,-2.817,1.358,,,H,A,0.44,-0.47,1.132,,63.64,HHH,-1.17833,0.111618,0.00492501,0.467655 kka2_1:2_D154S,kka2_1:2_154,Kka2,kka2_1:2,P00552,0.467658,NO,154,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.876,-3.211,2.335,,0.457,,b,0.29,1.48,3.631,,52.65,HAP,-1.52467,0.295029,0.00292633,0.467658 kka2_1:4_D220N,kka2_1:4_220,Kka2,kka2_1:4,P00552,0.467697,NO,220,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.787,-3.336,2.549,,,H,A,0.75,-1.14,1.237,,46.59,PAH,-1.152,0.168804,0.00158066,0.467697 kka2_1:2_D101C,kka2_1:2_101,Kka2,kka2_1:2,P00552,0.467714,NO,101,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.028,-5.093,4.065,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.295029,0.00423361,0.467714 Ubiquitin_F4D,Ubiquitin_4,Uba1,Ubiquitin,P0CG48,0.467742,NO,4,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.534,-3.794,2.26,4.77459,0.059,E,B,,-0.46,,,,HHH,-1.504,0.205827,0.000805043,0.467742 Ubiquitin_H68G,Ubiquitin_68,Uba1,Ubiquitin,P0CG48,0.467742,NO,68,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-1.869,-3.501,1.632,4.81902,0.194,E,B,0.72,-1.02,21.325,21.325,65.11,HBH,-1.583,0.205827,0.000925438,0.467742 Ubiquitin_L8S,Ubiquitin_8,Uba1,Ubiquitin,P0CG48,0.467742,NO,8,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.723,-3.503,1.78,5.28016,0.664,T,A,0.08,-0.34,0.664,,29.05,PHP,-1.51567,0.205827,0.000726165,0.467742 Ubiquitin_R72M,Ubiquitin_72,Uba1,Ubiquitin,P0CG48,0.467742,NO,72,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.034,-4.652,2.618,5.19484,0.077,,B,1.41,-0.1,9.638,9.638,42.77,HBH,-1.82733,0.205827,0.000768249,0.467742 kka2_1:4_L39D,kka2_1:4_39,Kka2,kka2_1:4,P00552,0.467809,NO,39,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.223,-4.127,2.904,,,E,B,0.55,-1.21,1.998,,71.59,BHP,-1.69167,0.168804,0.00493618,0.467809 beta-lactamase_156_W288T,beta-lactamase_156_288,TEM-1,beta-lactamase_156,P62593,0.467846,NO,288,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,,,,,,,,,,,,,BHO,,0.111618,,0.467846 kka2_1:1_I254W,kka2_1:1_254,Kka2,kka2_1:1,P00552,0.46787,NO,254,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.933,-5.273,3.34,,0.135,H,A,1.52,-0.6,1.859,,71.59,BHH,-1.668,0.520039,0.0132375,0.46787 kka2_1:8_P194M,kka2_1:8_194,Kka2,kka2_1:8,P00552,0.467913,NO,194,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.846,-4.773,3.927,,0.308,G,A,0.52,-1.19,4.861,,53.03,HOP,-0.888333,0.100394,0.00314194,0.467913 kka2_1:8_P194M,kka2_1:8_194,Kka2,kka2_1:8,P00552,0.467913,NO,194,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.846,-4.773,3.927,,0.308,G,A,0.52,-1.19,4.861,,53.03,HOP,-0.888333,0.100394,0.00314194,0.467913 Pab1_N127K,Pab1_127,Pab1,Pab1,P04147,0.467921,NO,127,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-1.079,-3.049,1.97,,0.138,E,B,1.05,-0.51,,,,OPH,-1.13633,0.175299,0.000805159,0.467921 kka2_1:2_C192P,kka2_1:2_192,Kka2,kka2_1:2,P00552,0.467985,NO,192,C,P,CP,Special,Special,5.07,6.3,1.23,169,121,115,-6,108.5,112.7,4.2,-1.067,-4.099,3.032,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.295029,0.00485428,0.467985 kka2_1:1_S204N,kka2_1:1_204,Kka2,kka2_1:1,P00552,0.468073,NO,204,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.353,-3.559,2.206,,0.144,E,A,0.27,-1.2,3.022,,65.53,HPO,-0.953333,0.520039,0.00881794,0.468073 beta-lactamase_2500_R162D,beta-lactamase_2500_162,TEM-1,beta-lactamase_2500,P62593,0.46809,NO,162,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.016,-3.754,2.738,,0.124,S,B,1.2,-0.37,6.199,,64.69,ABH,-1.25,0.361275,0.000561334,0.46809 kka2_1:2_D216E,kka2_1:2_216,Kka2,kka2_1:2,P00552,0.468146,NO,216,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.785,-2.854,2.069,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.295029,0.00229969,0.468146 beta-lactamase_2500_N168C,beta-lactamase_2500_168,TEM-1,beta-lactamase_2500,P62593,0.468168,NO,168,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-1.029,-4.99,3.961,,0.113,G,A,0.61,-0.4,2.9,,44.41,HPA,-1.13233,0.361275,0.00288667,0.468168 Pab1_I130K,Pab1_130,Pab1,Pab1,P04147,0.468192,NO,130,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.212,-3.724,2.512,,,E,B,1.23,0.01,,,,HHB,-1.188,0.175299,0.000351112,0.468192 kka2_1:4_V153H,kka2_1:4_153,Kka2,kka2_1:4,P00552,0.468194,NO,153,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.092,-4.991,3.899,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.168804,0.00501119,0.468194 beta-lactamase_2500_S241H,beta-lactamase_2500_241,TEM-1,beta-lactamase_2500,P62593,0.46823,NO,241,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.361275,0.00452736,0.46823 kka2_1:1_G55S,kka2_1:1_55,Kka2,kka2_1:1,P00552,0.468431,NO,55,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.625,-2.154,0.529,,0.517,S,b,0.29,1.19,4.035,,63.64,POH,-2.05967,0.520039,0.00667877,0.468431 beta-lactamase_625_A123H,beta-lactamase_625_123,TEM-1,beta-lactamase_625,P62593,0.46845,NO,123,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.834,-4.729,3.895,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.213352,0.0010157,0.46845 kka2_1:2_A119Y,kka2_1:2_119,Kka2,kka2_1:2,P00552,0.468468,NO,119,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.073,-4.266,3.193,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.295029,0.00441074,0.468468 beta-lactamase_2500_R220K,beta-lactamase_2500_220,TEM-1,beta-lactamase_2500,P62593,0.468507,NO,220,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-0.942,-2.865,1.923,,0.295,I,A,1.2,-0.76,2.175,,74.48,HBP,-1.33633,0.361275,0.00232421,0.468507 kka2_1:8_E262V,kka2_1:8_262,Kka2,kka2_1:8,P00552,0.468664,NO,262,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-0.829,-3.58,2.751,,0.059,G,A,1.52,-0.18,0.837,,42.42,AAH,-0.816,0.100394,0.0191586,0.468664 kka2_1:8_E262V,kka2_1:8_262,Kka2,kka2_1:8,P00552,0.468664,NO,262,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-0.829,-3.58,2.751,,0.059,G,A,1.52,-0.18,0.837,,42.42,AAH,-0.816,0.100394,0.0191586,0.468664 kka2_1:1_Q100T,kka2_1:1_100,Kka2,kka2_1:1,P00552,0.468753,NO,100,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.77,-2.757,-0.013,,0.646,E,B,0.4,-0.79,15.116,15.116,71.59,OPA,-1.46467,0.520039,0.0066405,0.468753 beta-lactamase_625_W208A,beta-lactamase_625_208,TEM-1,beta-lactamase_625,P62593,0.468776,NO,208,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-0.818,-3.528,2.71,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.213352,0.00126609,0.468776 beta-lactamase_625_R162L,beta-lactamase_625_162,TEM-1,beta-lactamase_625,P62593,0.468778,NO,162,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.016,-2.541,1.525,,0.124,S,B,1.2,-0.37,1.445,,64.69,ABH,-1.25,0.213352,0.000561334,0.468778 kka2_1:4_L260R,kka2_1:4_260,Kka2,kka2_1:4,P00552,0.468848,NO,260,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.741,-3.961,3.22,,0.022,H,A,0.55,-0.52,,,,HHA,-0.845667,0.168804,0.0233782,0.468848 beta-lactamase_2500_C121G,beta-lactamase_2500_121,TEM-1,beta-lactamase_2500,P62593,0.468897,NO,121,C,G,CG,Special,Special,5.07,3.29388,-1.77612,159,121,75,-46,108.5,60.1,-48.4,-0.953,-3.581,2.628,,,H,A,0.46,-0.81,1.174,,63.29,HOP,-1.46767,0.361275,0.000744322,0.468897 beta-lactamase_S201I,beta-lactamase_201,TEM-1,beta-lactamase,P62593,0.468998,NO,201,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.183,-3.765,2.582,4.85496,0.064,H,A,0.77,-0.07,4.045,,64.69,HPB,-1.451,0.221079,0.00198815,0.468998 beta-lactamase_2500_V260L,beta-lactamase_2500_260,TEM-1,beta-lactamase_2500,P62593,0.469001,NO,260,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.361275,0.00471757,0.469001 beta-lactamase_156_I245Y,beta-lactamase_156_245,TEM-1,beta-lactamase_156,P62593,0.469041,NO,245,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.111618,0.00391032,0.469041 beta-lactamase_2500_L111N,beta-lactamase_2500_111,TEM-1,beta-lactamase_2500,P62593,0.46908,NO,111,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.76,-4.132,2.372,,0.328,T,A,0.55,0.93,1.966,,64.34,BHP,-1.884,0.361275,0.00480671,0.46908 WW_domain_Q195G,WW_domain_195,Yap65,WW_domain,P46937,0.469124,NO,195,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-1.839,-3.284,1.445,5.22735,,,,,,1.803,,70.04,APP,-1.719,0.153962,0.00394344,0.469124 beta-lactamase_T178N,beta-lactamase_178,TEM-1,beta-lactamase,P62593,0.469135,NO,178,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-0.791,-3.448,2.657,5.06452,0.029,E,B,0.3,-1.07,,,,APP,-0.947667,0.221079,0.000684366,0.469135 PSD95pdz3_G329D,PSD95pdz3_329,PSD95pdz3,PSD95pdz3,P31016,0.46915,NO,329,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.008,-3.15,2.142,4.7671,,,,,19.7075,,,,HOO,-1.16033,0.0758425,0.000974577,0.46915 kka2_1:1_R226T,kka2_1:1_226,Kka2,kka2_1:1,P00552,0.469177,NO,226,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.392,-3.626,2.234,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.520039,0.0108032,0.469177 beta-lactamase_156_G76H,beta-lactamase_156_76,TEM-1,beta-lactamase_156,P62593,0.469183,NO,76,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.189,-4.754,3.565,,,H,A,0.29,-0.67,3.059,,67.83,OOH,-1.22267,0.111618,0.00476637,0.469183 kka2_1:4_F256M,kka2_1:4_256,Kka2,kka2_1:4,P00552,0.469257,NO,256,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.49,-4.553,3.063,,,H,A,0.58,-0.78,1.653,,53.03,HHH,-1.423,0.168804,0.0132841,0.469257 beta-lactamase_2500_S266Q,beta-lactamase_2500_266,TEM-1,beta-lactamase_2500,P62593,0.469317,NO,266,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.361275,0.0140785,0.469317 beta-lactamase_0_P181F,beta-lactamase_0_181,TEM-1,beta-lactamase_0,P62593,0.46934,NO,181,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.813,-4.48,3.667,,,H,A,0.52,-1.14,1.357,,61.54,HOH,-1.795,0.0500837,0.000703122,0.46934 beta-lactamase_P65Y,beta-lactamase_65,TEM-1,beta-lactamase,P62593,0.469356,NO,65,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.894,-4.31,3.416,5.59094,0.098,E,B,0.23,-0.62,0.623,,40.56,HOH,-1.03233,0.221079,0.00152776,0.469356 beta-lactamase_2500_W208D,beta-lactamase_2500_208,TEM-1,beta-lactamase_2500,P62593,0.469371,NO,208,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-0.818,-4.144,3.326,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.361275,0.00126609,0.469371 kka2_1:2_D118L,kka2_1:2_118,Kka2,kka2_1:2,P00552,0.46964,NO,118,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.07,-3.589,1.519,,0.61,H,A,0.75,-0.05,2.237,,64.39,HAH,-1.32367,0.295029,0.0067852,0.46964 beta-lactamase_156_G240M,beta-lactamase_156_240,TEM-1,beta-lactamase_156,P62593,0.469699,NO,240,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.111618,0.00591201,0.469699 Pab1_F149S,Pab1_149,Pab1,Pab1,P04147,0.469735,NO,149,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.149,-3.428,2.279,,0.183,T,A,1.33,1.09,,,,HHO,-1.27767,0.175299,0.000325688,0.469735 beta-lactamase_156_L150D,beta-lactamase_156_150,TEM-1,beta-lactamase_156,P62593,0.46974,NO,150,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.326,-4.043,2.717,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.111618,0.00463171,0.46974 beta-lactamase_2500_E56Y,beta-lactamase_2500_56,TEM-1,beta-lactamase_2500,P62593,0.469768,NO,56,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.043,-4.216,2.173,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.361275,0.00238534,0.469768 beta-lactamase_T158M,beta-lactamase_158,TEM-1,beta-lactamase,P62593,0.469774,NO,158,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.116,-4.575,3.459,5.32011,0.036,,B,0.98,-0.85,2.755,,69.58,HPB,-1.269,0.221079,0.00341825,0.469774 beta-lactamase_625_Y103R,beta-lactamase_625_103,TEM-1,beta-lactamase_625,P62593,0.469785,NO,103,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-1.33,-3.864,2.534,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.213352,0.00443048,0.469785 beta-lactamase_625_L79Q,beta-lactamase_625_79,TEM-1,beta-lactamase_625,P62593,0.469795,NO,79,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.842,-4.087,3.245,,0.007,H,A,0.55,-0.16,0.935,,50.35,HHP,-1.44333,0.213352,0.000947397,0.469795 kka2_1:1_L193P,kka2_1:1_193,Kka2,kka2_1:1,P00552,0.469795,NO,193,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.983,-2.872,1.889,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.520039,0.00480179,0.469795 kka2_1:4_W15S,kka2_1:4_15,Kka2,kka2_1:4,P00552,0.469818,NO,15,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-1.392,-3.829,2.437,,0.01,G,A,0.47,0.15,0.943,,52.27,HHH,-2.10533,0.168804,0.00585505,0.469818 beta-lactamase_2500_L192H,beta-lactamase_2500_192,TEM-1,beta-lactamase_2500,P62593,0.469821,NO,192,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.254,-4.926,3.672,,0.095,H,A,0.55,0.35,1.902,,60.14,HHP,-1.41833,0.361275,0.00558728,0.469821 PSD95pdz3_D348P,PSD95pdz3_348,PSD95pdz3,PSD95pdz3,P31016,0.469879,NO,348,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.264,-3.336,2.072,5.02473,,,,,16.8925,,,,HAH,-1.306,0.0758425,0.000731866,0.469879 kka2_1:1_L152E,kka2_1:1_152,Kka2,kka2_1:1,P00552,0.469932,NO,152,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.521,-3.005,1.484,,0.547,.,A,0.55,1.36,1.589,,63.64,OHH,-1.162,0.520039,0.00674868,0.469932 beta-lactamase_2500_I244W,beta-lactamase_2500_244,TEM-1,beta-lactamase_2500,P62593,0.469958,NO,244,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.555,-5.375,3.82,,,E,B,0.48,-0.84,1.683,,77.62,OHH,-1.385,0.361275,0.00605379,0.469958 kka2_1:1_E160A,kka2_1:1_160,Kka2,kka2_1:1,P00552,0.469964,NO,160,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.683,-2.356,0.673,,0.989,G,A,1.04,2.28,0.273,,71.59,AAA,-1.36133,0.520039,0.00935762,0.469964 kka2_1:8_F263V,kka2_1:8_263,Kka2,kka2_1:8,P00552,0.469987,NO,263,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-0.911,-3.287,2.376,,0.006,G,A,1.62,-0.12,0.928,,45.83,AHH,-0.92,0.100394,0.0172454,0.469987 kka2_1:8_F263V,kka2_1:8_263,Kka2,kka2_1:8,P00552,0.469987,NO,263,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-0.911,-3.287,2.376,,0.006,G,A,1.62,-0.12,0.928,,45.83,AHH,-0.92,0.100394,0.0172454,0.469987 kka2_1:1_A229T,kka2_1:1_229,Kka2,kka2_1:1,P00552,0.470046,NO,229,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.739,-2.302,0.563,,0.32,H,A,0.46,-0.7,6.549,,63.64,HHA,-1.851,0.520039,0.00942138,0.470046 hsp90_F583Q,hsp90_583,hsp90,hsp90,P02829,0.470062,NO,583,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-3.22,-3.278,0,5.28185,1.112,S,l,1.1,0.87,,,,PHO,-3.003,0.368192,0.000222939,0.470062 kka2_1:8_L259K,kka2_1:8_259,Kka2,kka2_1:8,P00552,0.47007,NO,259,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.088,-3.716,2.628,,0.036,H,A,1.59,-0.15,1.83,,48.48,BHH,-1.15167,0.100394,0.0206964,0.47007 kka2_1:8_L259K,kka2_1:8_259,Kka2,kka2_1:8,P00552,0.47007,NO,259,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.088,-3.716,2.628,,0.036,H,A,1.59,-0.15,1.83,,48.48,BHH,-1.15167,0.100394,0.0206964,0.47007 beta-lactamase_39_M209Y,beta-lactamase_39_209,TEM-1,beta-lactamase_39,P62593,0.470124,NO,209,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.442,-3.865,2.423,,,H,A,0.55,-0.97,1.167,,64.69,HHA,-1.52633,0.0495842,0.00625021,0.470124 beta-lactamase_156_F70E,beta-lactamase_156_70,TEM-1,beta-lactamase_156,P62593,0.470132,NO,70,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.169,-3.82,2.651,,,H,A,0.58,-1.34,1.918,,63.99,PHB,-0.980667,0.111618,0.00193499,0.470132 beta-lactamase_D83I,beta-lactamase_83,TEM-1,beta-lactamase,P62593,0.470152,NO,83,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.066,-4.081,3.015,5.40616,0.354,H,A,1.33,0.22,0.861,,48.95,HAH,-1.34733,0.221079,0.00205968,0.470152 beta-lactamase_0_S68Y,beta-lactamase_0_68,TEM-1,beta-lactamase_0,P62593,0.470167,NO,68,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-0.913,-4.188,3.275,,0.064,G,A,0.27,-1.03,1.441,,64.69,HPP,-1.37233,0.0500837,0.000800065,0.470167 kka2_1:1_L158E,kka2_1:1_158,Kka2,kka2_1:1,P00552,0.470173,NO,158,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.947,-3.926,1.979,,0.095,.,B,0.55,0.77,7.588,,63.64,AHA,-1.25333,0.520039,0.00529068,0.470173 beta-lactamase_2500_T27P,beta-lactamase_2500_27,TEM-1,beta-lactamase_2500,P62593,0.47019,NO,27,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.905,-1.921,0.016,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.361275,0.00306559,0.47019 kka2_1:4_R226H,kka2_1:4_226,Kka2,kka2_1:4,P00552,0.470214,NO,226,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.392,-2.664,1.272,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.168804,0.0108032,0.470214 beta-lactamase_2500_A215V,beta-lactamase_2500_215,TEM-1,beta-lactamase_2500,P62593,0.47029,NO,215,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.503,-3.464,1.961,,,,a,0.46,-0.93,3.516,,74.48,HHO,-1.42633,0.361275,0.00544007,0.47029 beta-lactamase_2500_G76F,beta-lactamase_2500_76,TEM-1,beta-lactamase_2500,P62593,0.470297,NO,76,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.189,-4.264,3.075,,,H,A,0.29,-0.67,1.012,,67.83,OOH,-1.22267,0.361275,0.00476637,0.470297 beta-lactamase_M209W,beta-lactamase_209,TEM-1,beta-lactamase,P62593,0.470345,NO,209,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.442,-4.979,3.537,5.44502,,H,A,1.75,-0.97,1.402,,64.69,HHA,-1.52633,0.221079,0.00625021,0.470345 kka2_1:4_R44P,kka2_1:4_44,Kka2,kka2_1:4,P00552,0.470347,NO,44,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.062,-4.075,2.013,,0.487,S,B,1.2,-0.35,5.71,,71.59,OBO,-1.80767,0.168804,0.00745043,0.470347 kka2_1:1_Q155A,kka2_1:1_155,Kka2,kka2_1:1,P00552,0.470442,NO,155,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.606,-2.225,-0.381,,0.525,T,A,0.4,1.49,4.415,,63.64,APA,-1.726,0.520039,0.00641853,0.470442 beta-lactamase_2500_P224N,beta-lactamase_2500_224,TEM-1,beta-lactamase_2500,P62593,0.470465,NO,224,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.893,-3.802,2.909,,0.383,,B,0.52,-0.3,2.666,,74.48,HOH,-1.26433,0.361275,0.00189564,0.470465 kka2_1:4_F240H,kka2_1:4_240,Kka2,kka2_1:4,P00552,0.470466,NO,240,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-0.911,-4.571,3.66,,,H,A,0.58,-1.21,5.798,,50.38,BHH,-1.67267,0.168804,0.00552543,0.470466 beta-lactamase_2500_R176G,beta-lactamase_2500_176,TEM-1,beta-lactamase_2500,P62593,0.470487,NO,176,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-0.863,-3.358,2.495,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.361275,0.00105554,0.470487 kka2_1:2_D82L,kka2_1:2_82,Kka2,kka2_1:2,P00552,0.470503,NO,82,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.946,-3.65,1.704,,0.341,E,b,0.75,0.52,11.923,11.923,63.64,HAH,-1.98,0.295029,0.00637516,0.470503 kka2_1:8_L241G,kka2_1:8_241,Kka2,kka2_1:8,P00552,0.470565,NO,241,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.158,-3.805,2.647,,0.08,H,A,1.59,-0.82,1.136,,63.26,HHH,-1.58533,0.100394,0.0117299,0.470565 kka2_1:8_L241G,kka2_1:8_241,Kka2,kka2_1:8,P00552,0.470565,NO,241,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.158,-3.805,2.647,,0.08,H,A,1.59,-0.82,1.136,,63.26,HHH,-1.58533,0.100394,0.0117299,0.470565 kka2_1:1_D23L,kka2_1:1_23,Kka2,kka2_1:1,P00552,0.470683,NO,23,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.459,-2.907,0.448,,0.695,E,B,0.75,-0.65,2.655,,65.53,HAH,-1.94033,0.520039,0.007195,0.470683 beta-lactamase_N168F,beta-lactamase_168,TEM-1,beta-lactamase,P62593,0.470694,NO,168,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-1.029,-4.27,3.241,5.42128,0.113,G,A,0.09,-0.4,1.211,,44.41,HPA,-1.13233,0.221079,0.00288667,0.470694 kka2_1:1_I246T,kka2_1:1_246,Kka2,kka2_1:1,P00552,0.470702,NO,246,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-2.008,-3.038,1.03,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.520039,0.0139479,0.470702 beta-lactamase_625_D212M,beta-lactamase_625_212,TEM-1,beta-lactamase_625,P62593,0.470758,NO,212,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.624,-4.83,3.206,,0.037,,b,0.75,-0.58,1.516,,74.48,HAB,-1.77667,0.213352,0.00644302,0.470758 kka2_1:2_T51M,kka2_1:2_51,Kka2,kka2_1:2,P00552,0.470781,NO,51,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.199,-4.634,2.435,,0.05,E,B,0.22,-0.05,13.165,13.165,63.64,BPA,-1.76767,0.295029,0.00628861,0.470781 beta-lactamase_2500_L73Y,beta-lactamase_2500_73,TEM-1,beta-lactamase_2500,P62593,0.470862,NO,73,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.507,-3.917,2.41,,,H,A,0.55,-0.64,2.178,,67.83,HHH,-1.487,0.361275,0.00488983,0.470862 kka2_1:8_V113E,kka2_1:8_113,Kka2,kka2_1:8,P00552,0.470903,NO,113,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.233,-3.887,2.654,,0.008,H,A,1.48,-1.17,1.254,,52.27,BHP,-2.08367,0.100394,0.00650191,0.470903 kka2_1:8_V113E,kka2_1:8_113,Kka2,kka2_1:8,P00552,0.470903,NO,113,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.233,-3.887,2.654,,0.008,H,A,1.48,-1.17,1.254,,52.27,BHP,-2.08367,0.100394,0.00650191,0.470903 beta-lactamase_R220D,beta-lactamase_220,TEM-1,beta-lactamase,P62593,0.470906,NO,220,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-0.942,-3.72,2.778,5.65995,0.295,I,A,0.68,-0.76,2.164,,74.48,HBP,-1.33633,0.221079,0.00232421,0.470906 beta-lactamase_2500_E35A,beta-lactamase_2500_35,TEM-1,beta-lactamase_2500,P62593,0.470937,NO,35,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-0.869,-3.127,2.258,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.361275,0.00174441,0.470937 beta-lactamase_156_R162W,beta-lactamase_156_162,TEM-1,beta-lactamase_156,P62593,0.470957,NO,162,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.016,-5.367,4.351,,0.124,S,B,1.2,-0.37,7.444,,64.69,ABH,-1.25,0.111618,0.000561334,0.470957 PSD95pdz3_G345I,PSD95pdz3_345,PSD95pdz3,PSD95pdz3,P31016,0.471013,NO,345,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.008,-3.917,2.909,4.32868,,,,,13.165,,,,OOO,-1.084,0.0758425,0.000771806,0.471013 kka2_1:8_V186Q,kka2_1:8_186,Kka2,kka2_1:8,P00552,0.471059,NO,186,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.011,-4.284,3.273,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.100394,0.00409703,0.471059 kka2_1:8_V186Q,kka2_1:8_186,Kka2,kka2_1:8,P00552,0.471059,NO,186,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.011,-4.284,3.273,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.100394,0.00409703,0.471059 kka2_1:1_E86G,kka2_1:1_86,Kka2,kka2_1:1,P00552,0.471135,NO,86,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.86,-2.302,0.442,,0.369,.,B,1.04,1.92,18.506,18.506,63.26,PAH,-1.98067,0.520039,0.00642858,0.471135 beta-lactamase_2500_Q204G,beta-lactamase_2500_204,TEM-1,beta-lactamase_2500,P62593,0.471168,NO,204,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-1.382,-3.474,2.092,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.361275,0.00364106,0.471168 kka2_1:1_A176Q,kka2_1:1_176,Kka2,kka2_1:1,P00552,0.471175,NO,176,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.621,-3.141,1.52,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.520039,0.0083587,0.471175 kka2_1:1_Q61A,kka2_1:1_61,Kka2,kka2_1:1,P00552,0.4712,NO,61,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.982,-1.987,-0.995,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.520039,0.00612092,0.4712 kka2_1:4_D220Y,kka2_1:4_220,Kka2,kka2_1:4,P00552,0.471242,NO,220,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.787,-4.383,3.596,,,H,A,0.75,-1.14,1.237,,46.59,PAH,-1.152,0.168804,0.00158066,0.471242 beta-lactamase_625_L205W,beta-lactamase_625_205,TEM-1,beta-lactamase_625,P62593,0.471247,NO,205,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.922,-4.959,4.037,,,H,A,0.55,-0.46,3.782,,42.31,PHH,-1.57767,0.213352,0.00255802,0.471247 beta-lactamase_2500_L79V,beta-lactamase_2500_79,TEM-1,beta-lactamase_2500,P62593,0.471271,NO,79,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.842,-2.879,2.037,,0.007,H,A,0.55,-0.16,0.823,,50.35,HHP,-1.44333,0.361275,0.000947397,0.471271 kka2_1:4_D216K,kka2_1:4_216,Kka2,kka2_1:4,P00552,0.471413,NO,216,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.785,-3.508,2.723,,0.018,E,B,0.75,-0.51,0.112,,19.32,HAB,-0.970333,0.168804,0.00229969,0.471413 kka2_1:1_A168P,kka2_1:1_168,Kka2,kka2_1:1,P00552,0.47153,NO,168,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.989,-3.241,1.252,,0.67,H,A,0.46,0.15,25.546,25.546,64.39,OHA,-2.12933,0.520039,0.00806773,0.47153 kka2_1:1_D157C,kka2_1:1_157,Kka2,kka2_1:1,P00552,0.471536,NO,157,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.993,-5.181,4.188,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.520039,0.0042313,0.471536 beta-lactamase_625_L120S,beta-lactamase_625_120,TEM-1,beta-lactamase_625,P62593,0.471637,NO,120,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.044,-3.66,2.616,,,H,A,0.55,-1.13,7.813,,64.69,AHO,-1.13633,0.213352,0.00143563,0.471637 kka2_1:1_V83E,kka2_1:1_83,Kka2,kka2_1:1,P00552,0.471657,NO,83,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-2.567,-2.291,-0.276,,0.358,E,B,0.44,0.53,5.931,,71.59,AHH,-2.264,0.520039,0.00650486,0.471657 kka2_1:1_L53D,kka2_1:1_53,Kka2,kka2_1:1,P00552,0.471688,NO,53,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-2.681,-2.935,0.254,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.520039,0.00671168,0.471688 beta-lactamase_T69Y,beta-lactamase_69,TEM-1,beta-lactamase,P62593,0.471748,NO,69,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-0.973,-4.223,3.25,5.16042,,G,A,0.69,-1.24,0.505,,93.01,PPH,-1.01833,0.221079,0.00127498,0.471748 kka2_1:4_V36P,kka2_1:4_36,Kka2,kka2_1:4,P00552,0.471869,NO,36,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-0.898,-3.99,3.092,,0.292,E,B,0.44,0.21,0.278,,52.27,HHH,-1.484,0.168804,0.00245633,0.471869 kka2_1:8_L260I,kka2_1:8_260,Kka2,kka2_1:8,P00552,0.471881,NO,260,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.741,-2.914,2.173,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.100394,0.0233782,0.471881 kka2_1:8_L260I,kka2_1:8_260,Kka2,kka2_1:8,P00552,0.471881,NO,260,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.741,-2.914,2.173,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.100394,0.0233782,0.471881 beta-lactamase_2500_Y95H,beta-lactamase_2500_95,TEM-1,beta-lactamase_2500,P62593,0.472068,NO,95,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-1.715,-3.182,1.467,,0.122,,b,0.21,-0.37,2.914,,77.62,BHP,-2.16167,0.361275,0.00479449,0.472068 kka2_1:1_T72N,kka2_1:1_72,Kka2,kka2_1:1,P00552,0.472176,NO,72,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.38,-3.767,1.387,,0.784,H,A,0.22,0.29,10.43,10.43,65.53,HPP,-2.238,0.520039,0.00750756,0.472176 beta-lactamase_625_G154W,beta-lactamase_625_154,TEM-1,beta-lactamase_625,P62593,0.472182,NO,154,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.823,-5.233,4.41,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.213352,0.00180205,0.472182 beta-lactamase_2500_F64M,beta-lactamase_2500_64,TEM-1,beta-lactamase_2500,P62593,0.472184,NO,64,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-0.841,-4.255,3.414,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.361275,0.000947691,0.472184 beta-lactamase_2500_L120V,beta-lactamase_2500_120,TEM-1,beta-lactamase_2500,P62593,0.472202,NO,120,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.044,-3.031,1.987,,,H,A,0.55,-1.13,2.48,,64.69,AHO,-1.13633,0.361275,0.00143563,0.472202 kka2_1:2_A255P,kka2_1:2_255,Kka2,kka2_1:2,P00552,0.472308,NO,255,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.715,-3.184,1.469,,0.466,H,A,0.46,-0.52,5.144,,65.53,HHH,-1.71267,0.295029,0.0126809,0.472308 kka2_1:8_M148N,kka2_1:8_148,Kka2,kka2_1:8,P00552,0.472373,NO,148,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.847,-4.17,2.323,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.100394,0.00982664,0.472373 kka2_1:8_M148N,kka2_1:8_148,Kka2,kka2_1:8,P00552,0.472373,NO,148,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.847,-4.17,2.323,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.100394,0.00982664,0.472373 beta-lactamase_2500_W288H,beta-lactamase_2500_288,TEM-1,beta-lactamase_2500,P62593,0.47239,NO,288,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,,,,,,,,,,,,,BHO,,0.361275,,0.47239 kka2_1:1_S104Q,kka2_1:1_104,Kka2,kka2_1:1,P00552,0.472413,NO,104,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.436,-3.082,1.646,,0.536,T,A,0.27,-1.11,5.49,,63.64,HPP,-1.91433,0.520039,0.00555207,0.472413 beta-lactamase_2500_D48G,beta-lactamase_2500_48,TEM-1,beta-lactamase_2500,P62593,0.472415,NO,48,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.101,-3.259,2.158,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.361275,0.0027273,0.472415 beta-lactamase_2500_N274H,beta-lactamase_2500_274,TEM-1,beta-lactamase_2500,P62593,0.472456,NO,274,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.361275,0.0110418,0.472456 kka2_1:1_E160V,kka2_1:1_160,Kka2,kka2_1:1,P00552,0.472512,NO,160,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.683,-3.733,2.05,,0.989,G,A,1.04,2.28,0.273,,71.59,AAA,-1.36133,0.520039,0.00935762,0.472512 kka2_1:1_R140P,kka2_1:1_140,Kka2,kka2_1:1,P00552,0.472536,NO,140,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.351,-3.937,2.586,,0.12,H,A,1.2,0.2,11.345,11.345,53.03,BBH,-1.885,0.520039,0.00430167,0.472536 kka2_1:1_P109S,kka2_1:1_109,Kka2,kka2_1:1,P00552,0.472601,NO,109,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.412,-2.854,1.442,,0.376,H,A,0.52,-1.25,18.506,18.506,65.53,HOH,-1.84567,0.520039,0.0070929,0.472601 kka2_1:4_H188N,kka2_1:4_188,Kka2,kka2_1:4,P00552,0.472661,NO,188,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-0.913,-3.295,2.382,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.168804,0.00273139,0.472661 kka2_1:8_D261H,kka2_1:8_261,Kka2,kka2_1:8,P00552,0.4727,NO,261,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.708,-4.483,3.775,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.100394,0.0224846,0.4727 kka2_1:8_D261H,kka2_1:8_261,Kka2,kka2_1:8,P00552,0.4727,NO,261,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.708,-4.483,3.775,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.100394,0.0224846,0.4727 beta-lactamase_K53P,beta-lactamase_53,TEM-1,beta-lactamase,P62593,0.47279,NO,53,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-2.313,-3.069,0.756,5.93654,0.589,,B,1.82,1.15,19.72,19.72,77.62,OBH,-2.1,0.221079,0.00383383,0.47279 kka2_1:1_E96V,kka2_1:1_96,Kka2,kka2_1:1,P00552,0.472812,NO,96,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.573,-2.716,0.143,,0.476,,B,1.52,-0.65,1.254,,71.59,OAH,-2.143,0.520039,0.00369441,0.472812 beta-lactamase_P20F,beta-lactamase_20,TEM-1,beta-lactamase,P62593,0.472814,NO,20,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.74,-4.233,2.493,,,,,,,0.368,,67.83,HOH,-1.765,0.221079,0.00235322,0.472814 kka2_1:4_Y257Q,kka2_1:4_257,Kka2,kka2_1:4,P00552,0.472821,NO,257,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-1.064,-4.113,3.049,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.168804,0.0148191,0.472821 kka2_1:1_R18M,kka2_1:1_18,Kka2,kka2_1:1,P00552,0.472829,NO,18,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.055,-3.102,1.047,,0.474,T,A,1.2,0.54,11.422,11.422,71.59,ABH,-1.821,0.520039,0.00724065,0.472829 beta-lactamase_625_L223G,beta-lactamase_625_223,TEM-1,beta-lactamase_625,P62593,0.472881,NO,223,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.055,-3.765,2.71,,0.27,,B,0.55,0.09,1.633,,74.48,HHO,-1.35033,0.213352,0.00372793,0.472881 kka2_1:1_L165I,kka2_1:1_165,Kka2,kka2_1:1,P00552,0.472904,NO,165,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-2.453,-3.855,1.402,,0.299,,B,1.59,1.12,2.47,,64.39,OHH,-1.90967,0.520039,0.00801161,0.472904 beta-lactamase_I11E,beta-lactamase_11,TEM-1,beta-lactamase,P62593,0.472968,NO,11,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.745,-3.721,1.976,,,,,,,3.135,,66.08,HHO,-1.79467,0.221079,0.00261325,0.472968 kka2_1:1_D156C,kka2_1:1_156,Kka2,kka2_1:1,P00552,0.473045,NO,156,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.696,-3.452,1.756,,0.884,T,A,0.75,1.87,1.044,,65.53,PAA,-1.765,0.520039,0.00926998,0.473045 beta-lactamase_2500_I258A,beta-lactamase_2500_258,TEM-1,beta-lactamase_2500,P62593,0.473049,NO,258,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.361275,0.007931,0.473049 kka2_1:1_A166H,kka2_1:1_166,Kka2,kka2_1:1,P00552,0.473206,NO,166,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.407,-4.764,2.357,,0.534,.,B,0.46,1.03,1.147,,71.59,HHO,-2.421,0.520039,0.00799912,0.473206 kka2_1:4_L158E,kka2_1:4_158,Kka2,kka2_1:4,P00552,0.473247,NO,158,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.947,-3.926,1.979,,0.095,,B,1.59,0.77,7.588,,63.64,AHA,-1.25333,0.168804,0.00529068,0.473247 kka2_1:2_H162Q,kka2_1:2_162,Kka2,kka2_1:2,P00552,0.47331,NO,162,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-2.319,-3.703,1.384,,0.071,G,A,0.17,1.01,3.187,,64.39,ABP,-2.02067,0.295029,0.00616145,0.47331 beta-lactamase_156_L74N,beta-lactamase_156_74,TEM-1,beta-lactamase_156,P62593,0.473397,NO,74,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.296,-4.114,2.818,,,H,A,0.55,-0.91,0.746,,50,HHO,-1.34933,0.111618,0.00493255,0.473397 kka2_1:1_E142L,kka2_1:1_142,Kka2,kka2_1:1,P00552,0.473486,NO,142,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.221,-3.056,0.835,,0.471,H,A,1.52,0.85,3.626,,65.53,HAB,-2.08033,0.520039,0.00748883,0.473486 beta-lactamase_156_V117R,beta-lactamase_156_117,TEM-1,beta-lactamase_156,P62593,0.473532,NO,117,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.53,-4.17,2.64,,,H,A,0.44,-0.34,1.182,,65.03,PHB,-1.741,0.111618,0.00467906,0.473532 beta-lactamase_2500_V260M,beta-lactamase_2500_260,TEM-1,beta-lactamase_2500,P62593,0.473631,NO,260,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.361275,0.00471757,0.473631 beta-lactamase_2500_V82G,beta-lactamase_2500_82,TEM-1,beta-lactamase_2500,P62593,0.473792,NO,82,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.325,-2.644,1.319,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.361275,0.00397046,0.473792 kka2_1:4_P98N,kka2_1:4_98,Kka2,kka2_1:4,P00552,0.473832,NO,98,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.526,-3.852,2.326,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.168804,0.00622754,0.473832 beta-lactamase_625_N130Q,beta-lactamase_625_130,TEM-1,beta-lactamase_625,P62593,0.47388,NO,130,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-0.798,-3.674,2.876,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.213352,0.000683376,0.47388 beta-lactamase_2500_S233C,beta-lactamase_2500_233,TEM-1,beta-lactamase_2500,P62593,0.473888,NO,233,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.886,-4.789,2.903,,0.016,E,B,0.27,-1.01,2.851,,77.62,BPO,-1.17267,0.361275,0.00311415,0.473888 E1_Ubiquitin_R72F,E1_Ubiquitin_72,Uba1,E1_Ubiquitin,P0CG63,0.473917,NO,72,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.184,-4.109,2.925,,0.077,,B,0.16,-0.1,,,,HBH,-1.08733,0.18783,0.00129853,0.473917 kka2_1:1_D156H,kka2_1:1_156,Kka2,kka2_1:1,P00552,0.473923,NO,156,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.696,-4.723,3.027,,0.884,T,A,0.75,1.87,1.044,,65.53,PAA,-1.765,0.520039,0.00926998,0.473923 beta-lactamase_156_I245G,beta-lactamase_156_245,TEM-1,beta-lactamase_156,P62593,0.473952,NO,245,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.111618,0.00391032,0.473952 beta-lactamase_P224W,beta-lactamase_224,TEM-1,beta-lactamase,P62593,0.473955,NO,224,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.893,-5.546,4.653,5.179,0.383,,B,0.99,-0.3,0.383,,74.48,HOH,-1.26433,0.221079,0.00189564,0.473955 beta-lactamase_39_V260E,beta-lactamase_39_260,TEM-1,beta-lactamase_39,P62593,0.474022,NO,260,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.0495842,0.00471757,0.474022 Pab1_S154W,Pab1_154,Pab1,Pab1,P04147,0.474071,NO,154,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.146,-5.14,3.994,,0.208,E,B,0.1,-0.75,,,,HPP,-1.408,0.175299,0.000319331,0.474071 beta-lactamase_2500_R242H,beta-lactamase_2500_242,TEM-1,beta-lactamase_2500,P62593,0.474083,NO,242,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.361275,0.00452879,0.474083 kka2_1:1_A64T,kka2_1:1_64,Kka2,kka2_1:1,P00552,0.474137,NO,64,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.496,-2.834,1.338,,0.039,H,A,0.46,-0.57,1.175,,56.06,AHH,-1.334,0.520039,0.00705578,0.474137 kka2_1:1_D180I,kka2_1:1_180,Kka2,kka2_1:1,P00552,0.474146,NO,180,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.416,-3.372,0.956,,1.03,S,a,0.75,1.5,1.534,,71.59,OAO,-2.02933,0.520039,0.00756412,0.474146 kka2_1:1_T130A,kka2_1:1_130,Kka2,kka2_1:1,P00552,0.474146,NO,130,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.392,-1.951,-0.441,,0.561,G,A,0.22,0.77,0.5,,92.05,HPO,-1.62633,0.520039,0.00804204,0.474146 kka2_1:8_D159C,kka2_1:8_159,Kka2,kka2_1:8,P00552,0.474171,NO,159,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.82,-5.15,4.33,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.100394,0.0030485,0.474171 kka2_1:8_D159C,kka2_1:8_159,Kka2,kka2_1:8,P00552,0.474171,NO,159,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.82,-5.15,4.33,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.100394,0.0030485,0.474171 kka2_1:8_F256Q,kka2_1:8_256,Kka2,kka2_1:8,P00552,0.474231,NO,256,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.49,-4.227,2.737,,,H,A,1.62,-0.78,1.713,,53.03,HHH,-1.423,0.100394,0.0132841,0.474231 kka2_1:8_F256Q,kka2_1:8_256,Kka2,kka2_1:8,P00552,0.474231,NO,256,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.49,-4.227,2.737,,,H,A,1.62,-0.78,1.713,,53.03,HHH,-1.423,0.100394,0.0132841,0.474231 beta-lactamase_2500_R91I,beta-lactamase_2500_91,TEM-1,beta-lactamase_2500,P62593,0.474276,NO,91,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.392,-4.049,2.657,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.361275,0.00380226,0.474276 kka2_1:1_D216L,kka2_1:1_216,Kka2,kka2_1:1,P00552,0.474322,NO,216,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.785,-3.835,3.05,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.520039,0.00229969,0.474322 kka2_1:1_V185R,kka2_1:1_185,Kka2,kka2_1:1,P00552,0.474329,NO,185,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.045,-4.178,3.133,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.520039,0.00367031,0.474329 beta-lactamase_2500_R81T,beta-lactamase_2500_81,TEM-1,beta-lactamase_2500,P62593,0.474386,NO,81,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.466,-3.547,2.081,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.361275,0.00499763,0.474386 beta-lactamase_156_A34D,beta-lactamase_156_34,TEM-1,beta-lactamase_156,P62593,0.474408,NO,34,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.059,-3.876,1.817,,,H,A,0.46,-0.54,3.614,,73.78,AHA,-1.74967,0.111618,0.00407913,0.474408 kka2_1:8_I196Y,kka2_1:8_196,Kka2,kka2_1:8,P00552,0.474497,NO,196,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-2.115,-2.902,0.787,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.100394,0.0107273,0.474497 kka2_1:8_I196Y,kka2_1:8_196,Kka2,kka2_1:8,P00552,0.474497,NO,196,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-2.115,-2.902,0.787,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.100394,0.0107273,0.474497 beta-lactamase_2500_L137A,beta-lactamase_2500_137,TEM-1,beta-lactamase_2500,P62593,0.474551,NO,137,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.03,-3.142,2.112,,,H,A,0.55,-0.38,0.769,,42.31,HHP,-1.58933,0.361275,0.00278599,0.474551 WW_domain_T198K,WW_domain_198,Yap65,WW_domain,P46937,0.474563,NO,198,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.451,-3.429,1.978,5.14348,,,,,,3.158,,70.04,PPH,-1.513,0.153962,0.00224534,0.474563 beta-lactamase_156_T158N,beta-lactamase_156_158,TEM-1,beta-lactamase_156,P62593,0.474572,NO,158,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.116,-3.488,2.372,,0.036,,B,0.22,-0.85,3.771,,69.58,HPB,-1.269,0.111618,0.00341825,0.474572 beta-lactamase_2500_A124I,beta-lactamase_2500_124,TEM-1,beta-lactamase_2500,P62593,0.474729,NO,124,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.181,-3.529,2.348,,,H,A,0.46,-0.9,0.314,,64.34,HHH,-1.152,0.361275,0.00481399,0.474729 kka2_1:1_R140Y,kka2_1:1_140,Kka2,kka2_1:1,P00552,0.474854,NO,140,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.351,-4.311,2.96,,0.12,H,A,1.2,0.2,11.345,11.345,53.03,BBH,-1.885,0.520039,0.00430167,0.474854 beta-lactamase_2500_P143C,beta-lactamase_2500_143,TEM-1,beta-lactamase_2500,P62593,0.474901,NO,143,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.967,-5.012,4.045,,0.075,H,A,0.52,-0.37,0.479,,66.78,OOB,-1.354,0.361275,0.00114551,0.474901 beta-lactamase_2500_G265W,beta-lactamase_2500_265,TEM-1,beta-lactamase_2500,P62593,0.474937,NO,265,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.361275,0.00811926,0.474937 kka2_1:4_P45I,kka2_1:4_45,Kka2,kka2_1:4,P00552,0.475,NO,45,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.774,-4.097,2.323,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.168804,0.00590481,0.475 kka2_1:1_D183T,kka2_1:1_183,Kka2,kka2_1:1,P00552,0.475021,NO,183,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.204,-3.525,2.321,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.520039,0.00426304,0.475021 kka2_1:1_R140H,kka2_1:1_140,Kka2,kka2_1:1,P00552,0.475024,NO,140,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.351,-4.514,3.163,,0.12,H,A,1.2,0.2,11.345,11.345,53.03,BBH,-1.885,0.520039,0.00430167,0.475024 beta-lactamase_2500_R176D,beta-lactamase_2500_176,TEM-1,beta-lactamase_2500,P62593,0.47513,NO,176,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-0.863,-3.694,2.831,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.361275,0.00105554,0.47513 kka2_1:1_A224V,kka2_1:1_224,Kka2,kka2_1:1,P00552,0.475159,NO,224,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.977,-2.571,1.594,,,H,A,0.46,-1.26,1.725,,63.64,HHP,-1.41033,0.520039,0.00352047,0.475159 kka2_1:1_I141C,kka2_1:1_141,Kka2,kka2_1:1,P00552,0.475242,NO,141,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.495,-4.812,3.317,,0.068,H,A,0.48,-0.01,7.546,7.546,92.05,BHA,-1.689,0.520039,0.00744745,0.475242 kka2_1:1_P109D,kka2_1:1_109,Kka2,kka2_1:1,P00552,0.475274,NO,109,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.412,-2.934,1.522,,0.376,H,A,0.52,-1.25,18.506,18.506,65.53,HOH,-1.84567,0.520039,0.0070929,0.475274 kka2_1:1_S105T,kka2_1:1_105,Kka2,kka2_1:1,P00552,0.475274,NO,105,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.945,-2.444,0.499,,0.056,S,B,0.27,-1.04,3.442,,65.53,PPB,-2.17033,0.520039,0.00847233,0.475274 beta-lactamase_2500_L135T,beta-lactamase_2500_135,TEM-1,beta-lactamase_2500,P62593,0.475285,NO,135,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.002,-3.475,2.473,,0.117,H,A,0.55,-0.58,0.795,,43.71,PHH,-1.03767,0.361275,0.00244423,0.475285 kka2_1:4_L170Y,kka2_1:4_170,Kka2,kka2_1:4,P00552,0.475291,NO,170,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.28,-4.115,2.835,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.168804,0.00730791,0.475291 WW_domain_L173R,WW_domain_173,Yap65,WW_domain,P46937,0.475392,NO,173,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.117,-3.71,2.593,,,,,,,,,,OHO,-1.06233,0.153962,0.000851849,0.475392 beta-lactamase_625_M115E,beta-lactamase_625_115,TEM-1,beta-lactamase_625,P62593,0.47543,NO,115,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.389,-3.76,2.371,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.213352,0.0034337,0.47543 kka2_1:2_I221P,kka2_1:2_221,Kka2,kka2_1:2,P00552,0.475531,NO,221,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.739,-4.232,2.493,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.295029,0.00945908,0.475531 beta-lactamase_156_T178R,beta-lactamase_156_178,TEM-1,beta-lactamase_156,P62593,0.475621,NO,178,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-0.791,-3.708,2.917,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.111618,0.000684366,0.475621 kka2_1:1_C131V,kka2_1:1_131,Kka2,kka2_1:1,P00552,0.475673,NO,131,C,V,CV,Special,Hydrophobic,5.07,5.60847,0.538465,192,121,117,-4,108.5,140,31.5,-0.831,-3.332,2.501,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.520039,0.00170814,0.475673 kka2_1:1_R239C,kka2_1:1_239,Kka2,kka2_1:1,P00552,0.475701,NO,239,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.949,-5.104,2.155,,0.15,H,A,1.2,-0.31,0.477,,71.59,ABH,-2.23,0.520039,0.00835326,0.475701 kka2_1:1_I221T,kka2_1:1_221,Kka2,kka2_1:1,P00552,0.475768,NO,221,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.739,-3.548,1.809,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.520039,0.00945908,0.475768 kka2_1:4_Y257C,kka2_1:4_257,Kka2,kka2_1:4,P00552,0.47578,NO,257,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-1.064,-4.949,3.885,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.168804,0.0148191,0.47578 kka2_1:1_T125I,kka2_1:1_125,Kka2,kka2_1:1,P00552,0.475794,NO,125,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.622,-3.99,1.368,,0.791,T,A,0.22,0.33,1.972,,92.05,BPH,-1.56933,0.520039,0.00821755,0.475794 kka2_1:8_A41P,kka2_1:8_41,Kka2,kka2_1:8,P00552,0.475797,NO,41,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.879,-2.834,0.955,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.100394,0.00543332,0.475797 kka2_1:8_A41P,kka2_1:8_41,Kka2,kka2_1:8,P00552,0.475797,NO,41,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.879,-2.834,0.955,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.100394,0.00543332,0.475797 kka2_1:4_E262Q,kka2_1:4_262,Kka2,kka2_1:4,P00552,0.475806,NO,262,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-0.829,-2.552,1.723,,0.059,G,A,1.04,-0.18,2.383,,42.42,AAH,-0.816,0.168804,0.0191586,0.475806 Ubiquitin_I61Q,Ubiquitin_61,Uba1,Ubiquitin,P0CG48,0.475806,NO,61,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.514,-4.181,2.667,5.19922,0.038,,B,1,-0.76,1.953,,24.53,PHP,-1.70833,0.205827,0.000738268,0.475806 WW_domain_D194P,WW_domain_194,Yap65,WW_domain,P46937,0.475869,NO,194,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.536,-3.699,2.163,5.95614,,,,,,1.948,,74.4,HAP,-1.78933,0.153962,0.00483742,0.475869 kka2_1:1_D159L,kka2_1:1_159,Kka2,kka2_1:1,P00552,0.475984,NO,159,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.82,-3.871,3.051,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.520039,0.0030485,0.475984 kka2_1:1_D190G,kka2_1:1_190,Kka2,kka2_1:1,P00552,0.47605,NO,190,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.708,-3.161,2.453,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.520039,0.00247989,0.47605 kka2_1:1_E169V,kka2_1:1_169,Kka2,kka2_1:1,P00552,0.476265,NO,169,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.996,-3.701,1.705,,0.422,H,A,1.04,0.3,7.546,7.546,65.53,HAH,-1.755,0.520039,0.00730086,0.476265 PSD95pdz3_I316W,PSD95pdz3_316,PSD95pdz3,PSD95pdz3,P31016,0.476292,NO,316,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.63,-5.004,3.374,5.46166,,,,,19.005,,,,HHB,-1.62733,0.0758425,0.00112762,0.476292 kka2_1:1_D208G,kka2_1:1_208,Kka2,kka2_1:1,P00552,0.476308,NO,208,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.708,-3.161,2.453,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.520039,0.00212588,0.476308 kka2_1:8_V36D,kka2_1:8_36,Kka2,kka2_1:8,P00552,0.476373,NO,36,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-0.898,-3.992,3.094,,0.292,E,B,1.48,0.21,0.938,,52.27,HHH,-1.484,0.100394,0.00245633,0.476373 kka2_1:8_V36D,kka2_1:8_36,Kka2,kka2_1:8,P00552,0.476373,NO,36,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-0.898,-3.992,3.094,,0.292,E,B,1.48,0.21,0.938,,52.27,HHH,-1.484,0.100394,0.00245633,0.476373 beta-lactamase_2500_E46G,beta-lactamase_2500_46,TEM-1,beta-lactamase_2500,P62593,0.47638,NO,46,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.94,-2.778,0.838,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.361275,0.00427568,0.47638 beta-lactamase_W208S,beta-lactamase_208,TEM-1,beta-lactamase,P62593,0.47642,NO,208,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-0.818,-3.836,3.018,5.26277,0.067,H,A,0.99,-0.65,,,,AHH,-1.44133,0.221079,0.00126609,0.47642 beta-lactamase_156_I229H,beta-lactamase_156_229,TEM-1,beta-lactamase_156,P62593,0.476435,NO,229,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.267,-4.969,3.702,,0.083,E,B,0.48,-0.76,1.114,,50,HHH,-1.58767,0.111618,0.00477249,0.476435 beta-lactamase_39_Y262E,beta-lactamase_39_262,TEM-1,beta-lactamase_39,P62593,0.476551,NO,262,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.0495842,0.00853516,0.476551 kka2_1:1_S40V,kka2_1:1_40,Kka2,kka2_1:1,P00552,0.476597,NO,40,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.645,-3.735,1.09,,0.32,E,B,0.27,-0.9,25.997,25.997,71.59,HPH,-1.91567,0.520039,0.00693477,0.476597 beta-lactamase_625_T27D,beta-lactamase_625_27,TEM-1,beta-lactamase_625,P62593,0.476621,NO,27,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.905,-3.5,1.595,,0.007,H,A,0.22,-0.37,3.72,,93.01,APH,-1.97933,0.213352,0.00306559,0.476621 kka2_1:4_N195T,kka2_1:4_195,Kka2,kka2_1:4,P00552,0.476672,NO,195,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-0.836,-3.268,2.432,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.168804,0.00276134,0.476672 kka2_1:4_G88L,kka2_1:4_88,Kka2,kka2_1:4,P00552,0.476679,NO,88,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.689,-3.754,2.065,,0.54,S,l,0.29,1.51,7.899,,65.53,HOB,-1.718,0.168804,0.00685559,0.476679 beta-lactamase_2500_G114A,beta-lactamase_2500_114,TEM-1,beta-lactamase_2500,P62593,0.476706,NO,114,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.094,-2.444,1.35,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.361275,0.00224919,0.476706 kka2_1:2_A119P,kka2_1:2_119,Kka2,kka2_1:2,P00552,0.476806,NO,119,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.073,-3.813,2.74,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.295029,0.00441074,0.476806 kka2_1:1_K138H,kka2_1:1_138,Kka2,kka2_1:1,P00552,0.476809,NO,138,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-2.5,-3.509,1.009,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.520039,0.00628542,0.476809 kka2_1:1_H135A,kka2_1:1_135,Kka2,kka2_1:1,P00552,0.476814,NO,135,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-1.331,-2.452,1.121,,0.071,.,a,0.17,0.65,3.574,,53.03,ABP,-1.77367,0.520039,0.00532566,0.476814 kka2_1:2_D227P,kka2_1:2_227,Kka2,kka2_1:2,P00552,0.476944,NO,227,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.758,-3.728,1.97,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.295029,0.00745029,0.476944 kka2_1:1_D134I,kka2_1:1_134,Kka2,kka2_1:1,P00552,0.476947,NO,134,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.969,-3.956,2.987,,0.421,B,B,0.75,0.31,2.329,,49.62,HAB,-1.057,0.520039,0.00270812,0.476947 kka2_1:1_D134P,kka2_1:1_134,Kka2,kka2_1:1,P00552,0.476947,NO,134,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.969,-3.811,2.842,,0.421,B,B,0.75,0.31,2.329,,49.62,HAB,-1.057,0.520039,0.00270812,0.476947 kka2_1:2_C192D,kka2_1:2_192,Kka2,kka2_1:2,P00552,0.476973,NO,192,C,D,CD,Special,negativeCharge,5.07,5.0516,-0.0184,154,121,133,12,108.5,111.1,2.6,-1.067,-3.871,2.804,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.295029,0.00485428,0.476973 beta-lactamase_2500_F149G,beta-lactamase_2500_149,TEM-1,beta-lactamase_2500,P62593,0.476995,NO,149,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.299,-3.587,2.288,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.361275,0.00418462,0.476995 beta-lactamase_0_A225K,beta-lactamase_0_225,TEM-1,beta-lactamase_0,P62593,0.477084,NO,225,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.845,-2.558,0.713,,1,T,B,0.46,-0.38,11.722,11.722,74.48,OHO,-1.39967,0.0500837,0.00465057,0.477084 beta-lactamase_2500_A40V,beta-lactamase_2500_40,TEM-1,beta-lactamase_2500,P62593,0.477103,NO,40,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.402,-2.649,1.247,,0.155,S,B,0.46,0.21,0.953,,73.78,OHB,-1.40267,0.361275,0.00490026,0.477103 Pab1_G150D,Pab1_150,Pab1,Pab1,P04147,0.477117,NO,150,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.809,-3.286,2.477,,0.287,S,b,0.23,0.53,,,,HOA,-1.45233,0.175299,0.000323835,0.477117 kka2_1:1_R122P,kka2_1:1_122,Kka2,kka2_1:1,P00552,0.477145,NO,122,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.175,-3.279,1.104,,0.487,H,A,1.2,0.26,1.356,,71.59,BBH,-1.53833,0.520039,0.00736512,0.477145 kka2_1:1_P128C,kka2_1:1_128,Kka2,kka2_1:1,P00552,0.477179,NO,128,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.922,-4.968,3.046,,0.316,G,A,0.52,0.4,2.178,,56.06,AOH,-1.64733,0.520039,0.00774689,0.477179 beta-lactamase_156_L192K,beta-lactamase_156_192,TEM-1,beta-lactamase_156,P62593,0.477261,NO,192,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.254,-3.803,2.549,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.111618,0.00558728,0.477261 beta-lactamase_625_P143R,beta-lactamase_625_143,TEM-1,beta-lactamase_625,P62593,0.47734,NO,143,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.967,-3.999,3.032,,0.075,H,A,0.52,-0.37,1.445,,66.78,OOB,-1.354,0.213352,0.00114551,0.47734 kka2_1:1_A110W,kka2_1:1_110,Kka2,kka2_1:1,P00552,0.477341,NO,110,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.064,-5.542,3.478,,0.175,H,A,1.04,-1.19,11.755,,71.59,OHA,-1.91867,0.520039,0.00759851,0.477341 kka2_1:4_S32C,kka2_1:4_32,Kka2,kka2_1:4,P00552,0.477345,NO,32,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-0.804,-4.665,3.861,,0.768,S,b,0.27,3.75,,,,OPA,-1.74533,0.168804,0.00149998,0.477345 beta-lactamase_625_G243N,beta-lactamase_625_243,TEM-1,beta-lactamase_625,P62593,0.477371,NO,243,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.213352,0.00464034,0.477371 hsp90_M589H,hsp90_589,hsp90,hsp90,P02829,0.477422,NO,589,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-3.858,-3.833,0,4.72723,0.032,H,A,0.84,0.31,,,,PHA,-3.24233,0.368192,0.000222939,0.477422 beta-lactamase_2500_K254P,beta-lactamase_2500_254,TEM-1,beta-lactamase_2500,P62593,0.477435,NO,254,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.361275,0.00369,0.477435 kka2_1:1_A166Q,kka2_1:1_166,Kka2,kka2_1:1,P00552,0.477453,NO,166,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.407,-3.207,0.8,,0.534,.,B,0.46,1.03,1.147,,71.59,HHO,-2.421,0.520039,0.00799912,0.477453 beta-lactamase_39_A230E,beta-lactamase_39_230,TEM-1,beta-lactamase_39,P62593,0.477466,NO,230,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.154,-3.566,2.412,,0.01,E,B,0.46,-1.17,1.171,,50,HHA,-1.079,0.0495842,0.00516841,0.477466 beta-lactamase_2500_D212P,beta-lactamase_2500_212,TEM-1,beta-lactamase_2500,P62593,0.47747,NO,212,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.624,-3.916,2.292,,0.037,,b,0.75,-0.58,12.482,,74.48,HAB,-1.77667,0.361275,0.00644302,0.47747 kka2_1:4_A119G,kka2_1:4_119,Kka2,kka2_1:4,P00552,0.477489,NO,119,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.073,-2.216,1.143,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.168804,0.00441074,0.477489 kka2_1:1_R145C,kka2_1:1_145,Kka2,kka2_1:1,P00552,0.477565,NO,145,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.804,-5.218,3.414,,0.346,H,A,1.2,1.23,23.699,23.699,63.64,HBP,-1.88033,0.520039,0.00846663,0.477565 beta-lactamase_39_I280Q,beta-lactamase_39_280,TEM-1,beta-lactamase_39,P62593,0.477657,NO,280,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.0495842,0.0530888,0.477657 beta-lactamase_39_L146K,beta-lactamase_39_146,TEM-1,beta-lactamase_39,P62593,0.47766,NO,146,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.462,-3.867,2.405,,0.007,H,A,0.55,-0.56,1.953,,64.69,AHP,-1.656,0.0495842,0.00474542,0.47766 beta-lactamase_0_L120T,beta-lactamase_0_120,TEM-1,beta-lactamase_0,P62593,0.477706,NO,120,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.044,-3.547,2.503,,,H,A,0.55,-1.13,1.2,,64.69,AHO,-1.13633,0.0500837,0.00143563,0.477706 beta-lactamase_2500_T69C,beta-lactamase_2500_69,TEM-1,beta-lactamase_2500,P62593,0.477729,NO,69,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-0.973,-4.661,3.688,,,G,A,0.22,-1.24,2.05,,93.01,PPH,-1.01833,0.361275,0.00127498,0.477729 kka2_1:1_E142Q,kka2_1:1_142,Kka2,kka2_1:1,P00552,0.477734,NO,142,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.221,-3.009,0.788,,0.471,H,A,1.52,0.85,3.626,,65.53,HAB,-2.08033,0.520039,0.00748883,0.477734 kka2_1:2_D157S,kka2_1:2_157,Kka2,kka2_1:2,P00552,0.477788,NO,157,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.993,-2.619,1.626,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.295029,0.0042313,0.477788 beta-lactamase_R220E,beta-lactamase_220,TEM-1,beta-lactamase,P62593,0.477794,NO,220,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-0.942,-3.264,2.322,5.65995,0.295,I,A,0.68,-0.76,2.164,,74.48,HBP,-1.33633,0.221079,0.00232421,0.477794 kka2_1:8_L94Y,kka2_1:8_94,Kka2,kka2_1:8,P00552,0.477818,NO,94,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.618,-4.101,2.483,,0.058,E,B,1.59,-0.52,2.197,,56.06,HHO,-1.612,0.100394,0.00520888,0.477818 kka2_1:8_L94Y,kka2_1:8_94,Kka2,kka2_1:8,P00552,0.477818,NO,94,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.618,-4.101,2.483,,0.058,E,B,1.59,-0.52,2.197,,56.06,HHO,-1.612,0.100394,0.00520888,0.477818 kka2_1:1_L60S,kka2_1:1_60,Kka2,kka2_1:1,P00552,0.477822,NO,60,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.997,-3.713,2.716,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.520039,0.00262176,0.477822 kka2_1:2_L70V,kka2_1:2_70,Kka2,kka2_1:2,P00552,0.477888,NO,70,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.017,-2.461,1.444,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.295029,0.00411884,0.477888 beta-lactamase_0_L150D,beta-lactamase_0_150,TEM-1,beta-lactamase_0,P62593,0.477889,NO,150,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.326,-4.043,2.717,,,H,A,0.55,-0.2,2.128,,62.94,HHB,-1.86167,0.0500837,0.00463171,0.477889 beta-lactamase_625_A123E,beta-lactamase_625_123,TEM-1,beta-lactamase_625,P62593,0.477974,NO,123,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.834,-3.489,2.655,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.213352,0.0010157,0.477974 beta-lactamase_L191E,beta-lactamase_191,TEM-1,beta-lactamase,P62593,0.477991,NO,191,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.087,-3.859,2.772,5.72226,,H,A,1.07,0.09,1.23,,63.29,BHH,-1.445,0.221079,0.00263549,0.477991 beta-lactamase_156_V72K,beta-lactamase_156_72,TEM-1,beta-lactamase_156,P62593,0.478087,NO,72,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.658,-3.754,2.096,,,H,A,0.44,-1.03,1.92,,65.73,BHH,-1.32167,0.111618,0.00501194,0.478087 kka2_1:8_S105F,kka2_1:8_105,Kka2,kka2_1:8,P00552,0.47814,NO,105,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.945,-4.371,2.426,,0.056,S,B,0.27,-1.04,2.115,,65.53,PPB,-2.17033,0.100394,0.00847233,0.47814 kka2_1:8_S105F,kka2_1:8_105,Kka2,kka2_1:8,P00552,0.47814,NO,105,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.945,-4.371,2.426,,0.056,S,B,0.27,-1.04,2.115,,65.53,PPB,-2.17033,0.100394,0.00847233,0.47814 beta-lactamase_0_G76S,beta-lactamase_0_76,TEM-1,beta-lactamase_0,P62593,0.478193,NO,76,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.189,-2.528,1.339,,,H,A,0.29,-0.67,1.188,,67.83,OOH,-1.22267,0.0500837,0.00476637,0.478193 kka2_1:1_G55N,kka2_1:1_55,Kka2,kka2_1:1,P00552,0.478244,NO,55,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.625,-3.05,1.425,,0.517,S,b,0.29,1.19,4.035,,63.64,POH,-2.05967,0.520039,0.00667877,0.478244 kka2_1:8_I141D,kka2_1:8_141,Kka2,kka2_1:8,P00552,0.478248,NO,141,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.495,-4.166,2.671,,0.068,H,A,1.52,-0.01,2.144,,92.05,BHA,-1.689,0.100394,0.00744745,0.478248 kka2_1:8_I141D,kka2_1:8_141,Kka2,kka2_1:8,P00552,0.478248,NO,141,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.495,-4.166,2.671,,0.068,H,A,1.52,-0.01,2.144,,92.05,BHA,-1.689,0.100394,0.00744745,0.478248 beta-lactamase_156_P65M,beta-lactamase_156_65,TEM-1,beta-lactamase_156,P62593,0.478259,NO,65,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.894,-4.494,3.6,,0.098,E,B,0.52,-0.62,0.623,,40.56,HOH,-1.03233,0.111618,0.00152776,0.478259 kka2_1:4_R38I,kka2_1:4_38,Kka2,kka2_1:4,P00552,0.4783,NO,38,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.207,-3.515,2.308,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.168804,0.00372499,0.4783 beta-lactamase_625_M115G,beta-lactamase_625_115,TEM-1,beta-lactamase_625,P62593,0.478352,NO,115,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.389,-3.632,2.243,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.213352,0.0034337,0.478352 kka2_1:4_K112F,kka2_1:4_112,Kka2,kka2_1:4,P00552,0.478381,NO,112,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-2.491,-4.227,1.736,,0.076,H,A,2.34,-1.37,0.39,,56.06,ABH,-2.00133,0.168804,0.00645389,0.478381 beta-lactamase_625_A247K,beta-lactamase_625_247,TEM-1,beta-lactamase_625,P62593,0.478404,NO,247,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.213352,0.00611275,0.478404 beta-lactamase_L188Q,beta-lactamase_188,TEM-1,beta-lactamase,P62593,0.478412,NO,188,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.166,-4.055,2.889,5.55434,,H,A,1.07,-0.3,1.574,,60.14,PHB,-1.47033,0.221079,0.00295687,0.478412 beta-lactamase_2500_Q276P,beta-lactamase_2500_276,TEM-1,beta-lactamase_2500,P62593,0.478531,NO,276,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.361275,0.0191712,0.478531 kka2_1:2_A150N,kka2_1:2_150,Kka2,kka2_1:2,P00552,0.478539,NO,150,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.949,-3.852,2.903,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.295029,0.0045009,0.478539 kka2_1:4_L184I,kka2_1:4_184,Kka2,kka2_1:4,P00552,0.478581,NO,184,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.496,-2.585,1.089,,0.489,E,B,1.59,-0.06,4.495,,63.26,AHH,-1.24833,0.168804,0.00518742,0.478581 beta-lactamase_0_I54W,beta-lactamase_0_54,TEM-1,beta-lactamase_0,P62593,0.478587,NO,54,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-2.838,-5.452,2.614,,0.669,E,B,0.48,-0.14,0.541,,73.78,BHH,-2.337,0.0500837,0.00403589,0.478587 kka2_1:1_L53H,kka2_1:1_53,Kka2,kka2_1:1,P00552,0.4786,NO,53,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-2.681,-4.842,2.161,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.520039,0.00671168,0.4786 beta-lactamase_G248N,beta-lactamase_248,TEM-1,beta-lactamase,P62593,0.478638,NO,248,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.794,-3.862,2.068,4.69798,,E,b,0.23,-0.43,1.782,,61.19,HOO,-1.52867,0.221079,0.00428493,0.478638 kka2_1:1_A110F,kka2_1:1_110,Kka2,kka2_1:1,P00552,0.478654,NO,110,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.064,-3.489,1.425,,0.175,H,A,1.04,-1.19,11.755,,71.59,OHA,-1.91867,0.520039,0.00759851,0.478654 kka2_1:1_F256C,kka2_1:1_256,Kka2,kka2_1:1,P00552,0.478676,NO,256,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.49,-3.289,1.799,,,H,A,1.62,-0.78,2.354,,53.03,HHH,-1.423,0.520039,0.0132841,0.478676 kka2_1:1_E235K,kka2_1:1_235,Kka2,kka2_1:1,P00552,0.478692,NO,235,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.955,-2.949,0.994,,0.631,H,A,1.52,0.12,8.521,,65.53,OAH,-2.07267,0.520039,0.0102806,0.478692 kka2_1:8_Q219W,kka2_1:8_219,Kka2,kka2_1:8,P00552,0.478784,NO,219,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-0.93,-5.169,4.239,,0.088,H,A,0.4,-0.85,0.897,,50,HPA,-1.05167,0.100394,0.00237913,0.478784 kka2_1:8_Q219W,kka2_1:8_219,Kka2,kka2_1:8,P00552,0.478784,NO,219,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-0.93,-5.169,4.239,,0.088,H,A,0.4,-0.85,0.897,,50,HPA,-1.05167,0.100394,0.00237913,0.478784 kka2_1:2_K50N,kka2_1:2_50,Kka2,kka2_1:2,P00552,0.478789,NO,50,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-0.833,-3.499,2.666,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.295029,0.00138626,0.478789 kka2_1:1_G10F,kka2_1:1_10,Kka2,kka2_1:1,P00552,0.478813,NO,10,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.921,-4.367,2.446,,,,,,,1.862,,71.59,HOP,-2.10733,0.520039,0.00289233,0.478813 beta-lactamase_625_C121V,beta-lactamase_625_121,TEM-1,beta-lactamase_625,P62593,0.478891,NO,121,C,V,CV,Special,Hydrophobic,5.07,5.60847,0.538465,192,121,117,-4,108.5,140,31.5,-0.953,-3.371,2.418,,,H,A,0.46,-0.81,1.143,,63.29,HOP,-1.46767,0.213352,0.000744322,0.478891 beta-lactamase_A40R,beta-lactamase_40,TEM-1,beta-lactamase,P62593,0.478898,NO,40,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.402,-3.924,2.522,4.9697,0.155,S,B,1.2,0.21,1.714,,73.78,OHB,-1.40267,0.221079,0.00490026,0.478898 beta-lactamase_156_R275P,beta-lactamase_156_275,TEM-1,beta-lactamase_156,P62593,0.478902,NO,275,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.111618,0.0141984,0.478902 kka2_1:4_G95P,kka2_1:4_95,Kka2,kka2_1:4,P00552,0.478943,NO,95,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-2.403,-3.948,1.545,,0.126,E,B,0.29,-0.74,0.359,,71.59,HOA,-2.198,0.168804,0.00743616,0.478943 WW_domain_R203S,WW_domain_203,Yap65,WW_domain,P46937,0.478963,NO,203,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.539,-3.107,1.568,5.41321,,,,,,1.9,,70.04,OBO,-1.4695,0.153962,0.00172433,0.478963 beta-lactamase_R220I,beta-lactamase_220,TEM-1,beta-lactamase,P62593,0.479106,NO,220,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-0.942,-3.974,3.032,5.65995,0.295,I,A,0.68,-0.76,2.164,,74.48,HBP,-1.33633,0.221079,0.00232421,0.479106 beta-lactamase_A245F,beta-lactamase_245,TEM-1,beta-lactamase,P62593,0.479152,NO,245,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.068,-4.156,3.088,4.78972,,E,B,0.17,-0.92,0.831,,64.69,HHH,-1.58133,0.221079,0.00391032,0.479152 beta-lactamase_2500_L49Q,beta-lactamase_2500_49,TEM-1,beta-lactamase_2500,P62593,0.47918,NO,49,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.897,-2.823,0.926,,0.131,T,A,0.55,0.04,6.681,,64.69,AHP,-1.99233,0.361275,0.00401477,0.47918 beta-lactamase_39_I277N,beta-lactamase_39_277,TEM-1,beta-lactamase_39,P62593,0.479214,NO,277,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.0495842,0.0169305,0.479214 E1_Ubiquitin_L43S,E1_Ubiquitin_43,Uba1,E1_Ubiquitin,P0CG63,0.479222,NO,43,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.188,-3.27,2.082,,,E,B,,-1.17,,,,BHH,-1.30733,0.18783,0.00190185,0.479222 beta-lactamase_2500_R273P,beta-lactamase_2500_273,TEM-1,beta-lactamase_2500,P62593,0.479244,NO,273,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.314,-2.669,0.355,,0.564,H,A,1.2,1.57,19.943,19.943,73.78,ABP,-1.841,0.361275,0.0077952,0.479244 beta-lactamase_625_A132C,beta-lactamase_625_132,TEM-1,beta-lactamase_625,P62593,0.479348,NO,132,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.9,-4.503,3.603,,,H,A,0.46,-0.93,0.316,,64.69,PHH,-1.138,0.213352,0.000962524,0.479348 kka2_1:4_P167N,kka2_1:4_167,Kka2,kka2_1:4,P00552,0.479351,NO,167,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-2.403,-3.993,1.59,,0.18,H,A,0.52,0.75,3.6,,64.39,HOH,-2.26633,0.168804,0.00543203,0.479351 beta-lactamase_625_T131P,beta-lactamase_625_131,TEM-1,beta-lactamase_625,P62593,0.479353,NO,131,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.328,-3.82,2.492,,,H,A,0.22,-0.69,2.031,,67.48,PPH,-1.00867,0.213352,0.00345886,0.479353 hsp90_A587C,hsp90_587,hsp90,hsp90,P02829,0.479368,NO,587,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.456,-4.015,0,4.91216,0.049,H,A,0.55,-0.02,,,,PHP,-2.757,0.368192,0.000222939,0.479368 kka2_1:4_L260Q,kka2_1:4_260,Kka2,kka2_1:4,P00552,0.479423,NO,260,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.741,-4.153,3.412,,0.022,H,A,0.55,-0.52,,,,HHA,-0.845667,0.168804,0.0233782,0.479423 kka2_1:8_L212R,kka2_1:8_212,Kka2,kka2_1:8,P00552,0.479506,NO,212,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.904,-4.001,3.097,,,,B,1.59,-0.78,1.708,,42.42,BHO,-0.799667,0.100394,0.0031426,0.479506 kka2_1:8_L212R,kka2_1:8_212,Kka2,kka2_1:8,P00552,0.479506,NO,212,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.904,-4.001,3.097,,,,B,1.59,-0.78,1.708,,42.42,BHO,-0.799667,0.100394,0.0031426,0.479506 kka2_1:1_K112F,kka2_1:1_112,Kka2,kka2_1:1,P00552,0.479508,NO,112,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-2.491,-4.227,1.736,,0.076,H,A,2.34,-1.37,23.433,23.433,56.06,ABH,-2.00133,0.520039,0.00645389,0.479508 beta-lactamase_39_A132V,beta-lactamase_39_132,TEM-1,beta-lactamase_39,P62593,0.479539,NO,132,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.9,-2.46,1.56,,,H,A,0.46,-0.93,8.408,,64.69,PHH,-1.138,0.0495842,0.000962524,0.479539 kka2_1:2_S104C,kka2_1:2_104,Kka2,kka2_1:2,P00552,0.479561,NO,104,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.436,-3.387,1.951,,0.536,T,A,0.27,-1.11,5.49,,63.64,HPP,-1.91433,0.295029,0.00555207,0.479561 beta-lactamase_2500_D231G,beta-lactamase_2500_231,TEM-1,beta-lactamase_2500,P62593,0.479574,NO,231,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.816,-3.182,2.366,,,E,B,0.75,-1.06,0.319,,65.38,HAB,-0.994,0.361275,0.00107395,0.479574 kka2_1:1_A176E,kka2_1:1_176,Kka2,kka2_1:1,P00552,0.479649,NO,176,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.621,-2.534,0.913,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.520039,0.0083587,0.479649 beta-lactamase_0_S128H,beta-lactamase_0_128,TEM-1,beta-lactamase_0,P62593,0.479668,NO,128,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-0.84,-4.455,3.615,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.0500837,0.00071483,0.479668 beta-lactamase_D174K,beta-lactamase_174,TEM-1,beta-lactamase,P62593,0.479719,NO,174,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.738,-3.457,2.719,5.44133,0.238,,B,1.22,-0.1,,,,PAA,-1.91233,0.221079,0.00125633,0.479719 beta-lactamase_2500_T158A,beta-lactamase_2500_158,TEM-1,beta-lactamase_2500,P62593,0.479782,NO,158,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.116,-2.879,1.763,,0.036,,B,0.22,-0.85,1.344,,69.58,HPB,-1.269,0.361275,0.00341825,0.479782 kka2_1:2_D261H,kka2_1:2_261,Kka2,kka2_1:2,P00552,0.479826,NO,261,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.708,-4.483,3.775,,0.146,G,A,0.75,-0.33,,,,HAA,-0.759333,0.295029,0.0224846,0.479826 beta-lactamase_625_R242L,beta-lactamase_625_242,TEM-1,beta-lactamase_625,P62593,0.479851,NO,242,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.213352,0.00452879,0.479851 beta-lactamase_625_L188G,beta-lactamase_625_188,TEM-1,beta-lactamase_625,P62593,0.479872,NO,188,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.166,-3.699,2.533,,,H,A,0.55,-0.3,2.982,,60.14,PHB,-1.47033,0.213352,0.00295687,0.479872 kka2_1:2_R258N,kka2_1:2_258,Kka2,kka2_1:2,P00552,0.479887,NO,258,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.626,-3.818,2.192,,0.316,H,A,1.2,-0.85,7.485,7.485,53.03,HBH,-1.25933,0.295029,0.00983174,0.479887 kka2_1:8_S204F,kka2_1:8_204,Kka2,kka2_1:8,P00552,0.479907,NO,204,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.353,-4.232,2.879,,0.144,E,A,0.27,-1.2,0.368,,65.53,HPO,-0.953333,0.100394,0.00881794,0.479907 kka2_1:8_S204F,kka2_1:8_204,Kka2,kka2_1:8,P00552,0.479907,NO,204,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.353,-4.232,2.879,,0.144,E,A,0.27,-1.2,0.368,,65.53,HPO,-0.953333,0.100394,0.00881794,0.479907 kka2_1:4_R140Y,kka2_1:4_140,Kka2,kka2_1:4,P00552,0.479928,NO,140,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.351,-4.311,2.96,,0.12,H,A,1.2,0.2,2.561,,53.03,BBH,-1.885,0.168804,0.00430167,0.479928 kka2_1:1_L126G,kka2_1:1_126,Kka2,kka2_1:1,P00552,0.479937,NO,126,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.246,-3.853,2.607,,0.285,S,B,0.55,0.12,0.302,,51.89,PHA,-1.744,0.520039,0.0066485,0.479937 kka2_1:1_E63K,kka2_1:1_63,Kka2,kka2_1:1,P00552,0.47994,NO,63,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-0.762,-3.035,2.273,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.520039,0.00118399,0.47994 beta-lactamase_0_Y103I,beta-lactamase_0_103,TEM-1,beta-lactamase_0,P62593,0.480041,NO,103,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-1.33,-3.874,2.544,,0.613,S,l,0.21,1.21,1.646,,63.29,AHP,-1.48767,0.0500837,0.00443048,0.480041 beta-lactamase_625_G226V,beta-lactamase_625_226,TEM-1,beta-lactamase_625,P62593,0.480046,NO,226,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.461,-3.807,2.346,,0.701,T,l,0.29,-0.25,3.199,,74.48,HOH,-1.42933,0.213352,0.00665294,0.480046 beta-lactamase_625_A123W,beta-lactamase_625_123,TEM-1,beta-lactamase_625,P62593,0.480074,NO,123,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.834,-5.348,4.514,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.213352,0.0010157,0.480074 kka2_1:1_S114N,kka2_1:1_114,Kka2,kka2_1:1,P00552,0.480086,NO,114,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.527,-3.164,0.637,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.520039,0.00705262,0.480086 beta-lactamase_2500_L150G,beta-lactamase_2500_150,TEM-1,beta-lactamase_2500,P62593,0.480101,NO,150,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.326,-3.622,2.296,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.361275,0.00463171,0.480101 beta-lactamase_2500_A247E,beta-lactamase_2500_247,TEM-1,beta-lactamase_2500,P62593,0.480138,NO,247,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.361275,0.00611275,0.480138 kka2_1:4_G205S,kka2_1:4_205,Kka2,kka2_1:4,P00552,0.480168,NO,205,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.596,-3.189,2.593,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.168804,0.00221855,0.480168 kka2_1:4_P109H,kka2_1:4_109,Kka2,kka2_1:4,P00552,0.480181,NO,109,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.412,-3.364,1.952,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.168804,0.0070929,0.480181 beta-lactamase_2500_A40I,beta-lactamase_2500_40,TEM-1,beta-lactamase_2500,P62593,0.480286,NO,40,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.402,-3.742,2.34,,0.155,S,B,0.46,0.21,0.953,,73.78,OHB,-1.40267,0.361275,0.00490026,0.480286 kka2_1:2_E17M,kka2_1:2_17,Kka2,kka2_1:2,P00552,0.480286,NO,17,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.154,-4.855,2.701,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.295029,0.00688738,0.480286 kka2_1:2_A144K,kka2_1:2_144,Kka2,kka2_1:2,P00552,0.480433,NO,144,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.859,-3.568,2.709,,,H,A,0.46,0.21,6.844,,52.65,BHB,-1.72933,0.295029,0.00231095,0.480433 beta-lactamase_625_T131Q,beta-lactamase_625_131,TEM-1,beta-lactamase_625,P62593,0.48046,NO,131,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.328,-3.951,2.623,,,H,A,0.22,-0.69,2.031,,67.48,PPH,-1.00867,0.213352,0.00345886,0.48046 beta-lactamase_2500_G141A,beta-lactamase_2500_141,TEM-1,beta-lactamase_2500,P62593,0.4805,NO,141,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.828,-2.988,2.16,,0.575,T,l,0.29,-0.28,1.493,,64.69,HOO,-1.08933,0.361275,0.0012419,0.4805 beta-lactamase_156_G236V,beta-lactamase_156_236,TEM-1,beta-lactamase_156,P62593,0.480567,NO,236,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.784,-3.686,2.902,,0.241,,b,0.29,-0.59,1.883,,64.69,HOO,-1.025,0.111618,0.00162372,0.480567 kka2_1:1_G99R,kka2_1:1_99,Kka2,kka2_1:1,P00552,0.480586,NO,99,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.596,-3.961,3.365,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.520039,0.00186055,0.480586 beta-lactamase_E119L,beta-lactamase_119,TEM-1,beta-lactamase,P62593,0.480633,NO,119,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.412,-3.669,2.257,5.33349,0.358,H,A,1.52,0.51,1.983,,63.99,BAH,-1.623,0.221079,0.00386966,0.480633 beta-lactamase_S51P,beta-lactamase_51,TEM-1,beta-lactamase,P62593,0.480633,NO,51,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.526,-3.858,2.332,5.06164,0.496,T,A,0.25,0.26,1.699,,72.73,PPO,-1.88467,0.221079,0.00504821,0.480633 kka2_1:2_A255V,kka2_1:2_255,Kka2,kka2_1:2,P00552,0.480689,NO,255,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.715,-3.655,1.94,,0.466,H,A,0.46,-0.52,5.144,,65.53,HHH,-1.71267,0.295029,0.0126809,0.480689 kka2_1:4_A64D,kka2_1:4_64,Kka2,kka2_1:4,P00552,0.480729,NO,64,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.496,-3.892,2.396,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.168804,0.00705578,0.480729 beta-lactamase_156_I245N,beta-lactamase_156_245,TEM-1,beta-lactamase_156,P62593,0.480745,NO,245,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.111618,0.00391032,0.480745 kka2_1:4_R38Y,kka2_1:4_38,Kka2,kka2_1:4,P00552,0.480792,NO,38,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.207,-4.179,2.972,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.168804,0.00372499,0.480792 kka2_1:1_A71R,kka2_1:1_71,Kka2,kka2_1:1,P00552,0.480814,NO,71,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.824,-2.453,0.629,,0.553,H,A,0.46,0.08,9.788,,64.39,HHP,-1.74033,0.520039,0.00727707,0.480814 kka2_1:2_R140C,kka2_1:2_140,Kka2,kka2_1:2,P00552,0.480851,NO,140,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.351,-5.118,3.767,,0.12,H,A,1.2,0.2,0.352,,53.03,BBH,-1.885,0.295029,0.00430167,0.480851 kka2_1:1_M120W,kka2_1:1_120,Kka2,kka2_1:1,P00552,0.480881,NO,120,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-3.877,-5.169,1.292,,,H,A,0.55,-0.42,2.259,,92.05,HHB,-2.16733,0.520039,0.00265808,0.480881 kka2_1:1_T225V,kka2_1:1_225,Kka2,kka2_1:1,P00552,0.480924,NO,225,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.393,-2.516,0.123,,0.036,H,A,0.22,-1.22,4.554,,63.64,HPB,-1.58733,0.520039,0.0113598,0.480924 kka2_1:1_A71Q,kka2_1:1_71,Kka2,kka2_1:1,P00552,0.480933,NO,71,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.824,-2.665,0.841,,0.553,H,A,0.46,0.08,9.788,,64.39,HHP,-1.74033,0.520039,0.00727707,0.480933 beta-lactamase_625_A215F,beta-lactamase_625_215,TEM-1,beta-lactamase_625,P62593,0.480992,NO,215,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.503,-4.278,2.775,,,,a,0.46,-0.93,3.583,,74.48,HHO,-1.42633,0.213352,0.00544007,0.480992 kka2_1:2_L92F,kka2_1:2_92,Kka2,kka2_1:2,P00552,0.481026,NO,92,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.893,-3.727,2.834,,0.007,E,B,1.59,-0.19,1.447,,63.26,HHH,-0.962,0.295029,0.00307177,0.481026 kka2_1:8_F203N,kka2_1:8_203,Kka2,kka2_1:8,P00552,0.481066,NO,203,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-0.911,-4.185,3.274,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.100394,0.00318738,0.481066 kka2_1:8_F203N,kka2_1:8_203,Kka2,kka2_1:8,P00552,0.481066,NO,203,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-0.911,-4.185,3.274,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.100394,0.00318738,0.481066 kka2_1:1_G245A,kka2_1:1_245,Kka2,kka2_1:1,P00552,0.481077,NO,245,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.812,-2.418,1.606,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.520039,0.00683899,0.481077 kka2_1:4_L170F,kka2_1:4_170,Kka2,kka2_1:4,P00552,0.481137,NO,170,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.28,-3.877,2.597,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.168804,0.00730791,0.481137 kka2_1:4_D52W,kka2_1:4_52,Kka2,kka2_1:4,P00552,0.481142,NO,52,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.271,-5.394,3.123,,0.22,E,B,0.75,0.8,0.349,,71.59,PAH,-2.38367,0.168804,0.00175694,0.481142 beta-lactamase_2500_I140W,beta-lactamase_2500_140,TEM-1,beta-lactamase_2500,P62593,0.481177,NO,140,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.733,-5.289,3.556,,0.128,H,A,0.48,0.41,1.628,,73.08,PHO,-1.48733,0.361275,0.00597777,0.481177 kka2_1:8_S104P,kka2_1:8_104,Kka2,kka2_1:8,P00552,0.481217,NO,104,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.436,-3.932,2.496,,0.536,T,A,0.27,-1.11,1.689,,63.64,HPP,-1.91433,0.100394,0.00555207,0.481217 kka2_1:8_S104P,kka2_1:8_104,Kka2,kka2_1:8,P00552,0.481217,NO,104,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.436,-3.932,2.496,,0.536,T,A,0.27,-1.11,1.689,,63.64,HPP,-1.91433,0.100394,0.00555207,0.481217 kka2_1:1_F133L,kka2_1:1_133,Kka2,kka2_1:1,P00552,0.481256,NO,133,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-0.871,-2.98,2.109,,0.178,.,B,0.58,0.43,1.999,,42.42,OHA,-0.871667,0.520039,0.00182168,0.481256 kka2_1:1_F37V,kka2_1:1_37,Kka2,kka2_1:1,P00552,0.481281,NO,37,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.427,-2.858,1.431,,0.219,E,B,0.58,-0.25,18.64,18.64,64.39,HHB,-1.17733,0.520039,0.00586193,0.481281 beta-lactamase_39_G249I,beta-lactamase_39_249,TEM-1,beta-lactamase_39,P62593,0.481296,NO,249,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.312,,,,0.256,S,B,0.23,0.04,30.841,30.841,72.73,HOO,-1.81367,0.0495842,0.00220169,0.481296 kka2_1:1_A119R,kka2_1:1_119,Kka2,kka2_1:1,P00552,0.481318,NO,119,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.073,-3.886,2.813,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.520039,0.00441074,0.481318 beta-lactamase_2500_G76Y,beta-lactamase_2500_76,TEM-1,beta-lactamase_2500,P62593,0.481336,NO,76,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.189,-4.36,3.171,,,H,A,0.29,-0.67,1.012,,67.83,OOH,-1.22267,0.361275,0.00476637,0.481336 beta-lactamase_2500_E102C,beta-lactamase_2500_102,TEM-1,beta-lactamase_2500,P62593,0.481361,NO,102,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.118,-5.064,2.946,,0.722,S,B,1.04,1.82,1.336,,73.08,HAH,-1.581,0.361275,0.00486633,0.481361 kka2_1:2_V36C,kka2_1:2_36,Kka2,kka2_1:2,P00552,0.481448,NO,36,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-0.898,-4.71,3.812,,0.292,E,B,1.48,0.21,1.064,,52.27,HHH,-1.484,0.295029,0.00245633,0.481448 kka2_1:4_L60H,kka2_1:4_60,Kka2,kka2_1:4,P00552,0.481452,NO,60,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.997,-4.966,3.969,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.168804,0.00262176,0.481452 beta-lactamase_2500_L191W,beta-lactamase_2500_191,TEM-1,beta-lactamase_2500,P62593,0.481458,NO,191,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.087,-5.14,4.053,,,H,A,0.55,0.09,1.703,,63.29,BHH,-1.445,0.361275,0.00263549,0.481458 kka2_1:1_P12D,kka2_1:1_12,Kka2,kka2_1:1,P00552,0.481511,NO,12,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.853,-3.54,2.687,,,.,B,0.52,1.25,0.261,,48.11,POH,-1.80767,0.520039,0.00500011,0.481511 kka2_1:4_L170G,kka2_1:4_170,Kka2,kka2_1:4,P00552,0.481537,NO,170,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.28,-3.713,2.433,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.168804,0.00730791,0.481537 kka2_1:4_L93A,kka2_1:4_93,Kka2,kka2_1:4,P00552,0.481554,NO,93,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.815,-3.129,2.314,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.168804,0.00131498,0.481554 beta-lactamase_M180P,beta-lactamase_180,TEM-1,beta-lactamase,P62593,0.481555,NO,180,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-2.795,-2.76,-0.035,4.96809,0.242,,B,1.07,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.221079,0.00552048,0.481555 kka2_1:8_W91A,kka2_1:8_91,Kka2,kka2_1:8,P00552,0.481585,NO,91,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-1.178,-3.5,2.322,,0.077,E,B,1.51,0.27,2.51,,48.48,AHH,-1.51,0.100394,0.00358653,0.481585 kka2_1:8_W91A,kka2_1:8_91,Kka2,kka2_1:8,P00552,0.481585,NO,91,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-1.178,-3.5,2.322,,0.077,E,B,1.51,0.27,2.51,,48.48,AHH,-1.51,0.100394,0.00358653,0.481585 beta-lactamase_0_Y262F,beta-lactamase_0_262,TEM-1,beta-lactamase_0,P62593,0.481656,NO,262,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.0500837,0.00853516,0.481656 beta-lactamase_625_L223N,beta-lactamase_625_223,TEM-1,beta-lactamase_625,P62593,0.481717,NO,223,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.055,-4.1,3.045,,0.27,,B,0.55,0.09,1.633,,74.48,HHO,-1.35033,0.213352,0.00372793,0.481717 kka2_1:2_D101Y,kka2_1:2_101,Kka2,kka2_1:2,P00552,0.481775,NO,101,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.028,-4.399,3.371,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.295029,0.00423361,0.481775 beta-lactamase_G114V,beta-lactamase_114,TEM-1,beta-lactamase,P62593,0.481796,NO,114,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.094,-3.65,2.556,4.92659,0.011,,p,0.77,0.35,2.148,,41.61,AOH,-1.43733,0.221079,0.00224919,0.481796 kka2_1:8_N195L,kka2_1:8_195,Kka2,kka2_1:8,P00552,0.481824,NO,195,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-0.836,-3.655,2.819,,0.037,G,A,0.43,-1.36,1.108,,48.11,OPH,-1.26567,0.100394,0.00276134,0.481824 kka2_1:8_N195L,kka2_1:8_195,Kka2,kka2_1:8,P00552,0.481824,NO,195,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-0.836,-3.655,2.819,,0.037,G,A,0.43,-1.36,1.108,,48.11,OPH,-1.26567,0.100394,0.00276134,0.481824 kka2_1:4_P194L,kka2_1:4_194,Kka2,kka2_1:4,P00552,0.481858,NO,194,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.846,-3.652,2.806,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.168804,0.00314194,0.481858 beta-lactamase_2500_S51F,beta-lactamase_2500_51,TEM-1,beta-lactamase_2500,P62593,0.481871,NO,51,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.526,-4.284,2.758,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.361275,0.00504821,0.481871 beta-lactamase_625_R220G,beta-lactamase_625_220,TEM-1,beta-lactamase_625,P62593,0.481933,NO,220,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-0.942,-3.321,2.379,,0.295,I,A,1.2,-0.76,5.086,,74.48,HBP,-1.33633,0.213352,0.00232421,0.481933 gb1_K254S,gb1_254,gb1,gb1,P06654,0.482047,NO,254,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.748,-3.026,1.278,,,,,,,1.793,,37.28,ABH,-2.195,0.177985,0.00622711,0.482047 gb1_K254W,gb1_254,gb1,gb1,P06654,0.482047,NO,254,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.748,-5.127,3.379,,,,,,,1.793,,37.28,ABH,-2.195,0.177985,0.00622711,0.482047 gb1_T244P,gb1_244,gb1,gb1,P06654,0.482047,NO,244,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.637,-3.572,1.935,,,,,,,0.202,,11.83,PPA,-1.92567,0.177985,0.00222755,0.482047 gb1_Y271T,gb1_271,gb1,gb1,P06654,0.482047,NO,271,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-1.181,-3.423,2.242,,,,,,,,,,PHA,-1.92933,0.177985,0.00236544,0.482047 kka2_1:1_K175N,kka2_1:1_175,Kka2,kka2_1:1,P00552,0.482087,NO,175,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-2.897,-4.012,1.115,,0.579,H,A,1.3,0.51,9.33,9.33,71.59,HBH,-1.82333,0.520039,0.00693093,0.482087 kka2_1:2_I221T,kka2_1:2_221,Kka2,kka2_1:2,P00552,0.482146,NO,221,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.739,-3.548,1.809,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.295029,0.00945908,0.482146 kka2_1:2_I115S,kka2_1:2_115,Kka2,kka2_1:2,P00552,0.482221,NO,115,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.606,-2.994,1.388,,0.105,H,A,0.48,-1.18,0.878,,65.53,PHH,-2.205,0.295029,0.00836567,0.482221 kka2_1:2_G99T,kka2_1:2_99,Kka2,kka2_1:2,P00552,0.482264,NO,99,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.596,-3.675,3.079,,0.368,S,g,0.29,-0.87,,,,OOP,-1.63067,0.295029,0.00186055,0.482264 kka2_1:8_S104W,kka2_1:8_104,Kka2,kka2_1:8,P00552,0.482381,NO,104,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.436,-5.482,4.046,,0.536,T,A,0.27,-1.11,1.689,,63.64,HPP,-1.91433,0.100394,0.00555207,0.482381 kka2_1:8_S104W,kka2_1:8_104,Kka2,kka2_1:8,P00552,0.482381,NO,104,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.436,-5.482,4.046,,0.536,T,A,0.27,-1.11,1.689,,63.64,HPP,-1.91433,0.100394,0.00555207,0.482381 kka2_1:2_R38F,kka2_1:2_38,Kka2,kka2_1:2,P00552,0.482394,NO,38,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.207,-4.103,2.896,,0.355,E,B,1.2,-1.13,6.872,6.872,52.27,HBH,-1.28567,0.295029,0.00372499,0.482394 kka2_1:1_E235G,kka2_1:1_235,Kka2,kka2_1:1,P00552,0.482405,NO,235,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.955,-2.889,0.934,,0.631,H,A,1.52,0.12,8.521,,65.53,OAH,-2.07267,0.520039,0.0102806,0.482405 kka2_1:8_R239P,kka2_1:8_239,Kka2,kka2_1:8,P00552,0.48246,NO,239,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.949,-1.624,-1.325,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.100394,0.00835326,0.48246 kka2_1:8_R239P,kka2_1:8_239,Kka2,kka2_1:8,P00552,0.48246,NO,239,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.949,-1.624,-1.325,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.100394,0.00835326,0.48246 beta-lactamase_625_I277T,beta-lactamase_625_277,TEM-1,beta-lactamase_625,P62593,0.482512,NO,277,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.213352,0.0169305,0.482512 kka2_1:2_R239I,kka2_1:2_239,Kka2,kka2_1:2,P00552,0.482518,NO,239,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.949,-3.142,0.193,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.295029,0.00835326,0.482518 beta-lactamase_2500_G154C,beta-lactamase_2500_154,TEM-1,beta-lactamase_2500,P62593,0.482592,NO,154,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.823,-5.058,4.235,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.361275,0.00180205,0.482592 kka2_1:4_L174R,kka2_1:4_174,Kka2,kka2_1:4,P00552,0.482698,NO,174,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.952,-4.019,3.067,,,H,A,0.55,-0.31,1.339,,51.89,BHB,-2.08533,0.168804,0.00438501,0.482698 beta-lactamase_2500_G141L,beta-lactamase_2500_141,TEM-1,beta-lactamase_2500,P62593,0.482707,NO,141,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.828,-3.844,3.016,,0.575,T,l,0.29,-0.28,1.493,,64.69,HOO,-1.08933,0.361275,0.0012419,0.482707 kka2_1:1_L165S,kka2_1:1_165,Kka2,kka2_1:1,P00552,0.482715,NO,165,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-2.453,-3.581,1.128,,0.299,,B,1.59,1.12,2.47,,64.39,OHH,-1.90967,0.520039,0.00801161,0.482715 kka2_1:8_I254P,kka2_1:8_254,Kka2,kka2_1:8,P00552,0.482778,NO,254,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.933,-4.189,2.256,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.100394,0.0132375,0.482778 kka2_1:8_I254P,kka2_1:8_254,Kka2,kka2_1:8,P00552,0.482778,NO,254,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.933,-4.189,2.256,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.100394,0.0132375,0.482778 kka2_1:4_W91D,kka2_1:4_91,Kka2,kka2_1:4,P00552,0.482812,NO,91,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-1.178,-4.116,2.938,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.168804,0.00358653,0.482812 Pab1_F168T,Pab1_168,Pab1,Pab1,P04147,0.482838,NO,168,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.269,-3.517,2.248,,,,,,,0.789,,56.33,OHO,-1.10033,0.175299,0.00064061,0.482838 kka2_1:1_S40N,kka2_1:1_40,Kka2,kka2_1:1,P00552,0.482853,NO,40,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.645,-3.752,1.107,,0.32,E,B,0.27,-0.9,25.997,25.997,71.59,HPH,-1.91567,0.520039,0.00693477,0.482853 kka2_1:1_C209S,kka2_1:1_209,Kka2,kka2_1:1,P00552,0.482856,NO,209,C,S,CS,Special,Polar,5.07,5.68,0.61,112,121,105,-16,108.5,89,-19.5,-0.906,-3.458,2.552,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.520039,0.00260862,0.482856 kka2_1:4_H135T,kka2_1:4_135,Kka2,kka2_1:4,P00552,0.482868,NO,135,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-1.331,-3.65,2.319,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.168804,0.00532566,0.482868 beta-lactamase_V72F,beta-lactamase_72,TEM-1,beta-lactamase,P62593,0.482906,NO,72,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.658,-3.023,1.365,5.80324,,H,A,2.78,-1.03,2.964,,65.73,BHH,-1.32167,0.221079,0.00501194,0.482906 kka2_1:1_Q27E,kka2_1:1_27,Kka2,kka2_1:1,P00552,0.482964,NO,27,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-1.659,-2.681,1.022,,0.608,.,A,0.64,0.71,0.521,,65.53,PPP,-1.90733,0.520039,0.00595365,0.482964 kka2_1:4_D220T,kka2_1:4_220,Kka2,kka2_1:4,P00552,0.482998,NO,220,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.787,-3.448,2.661,,,H,A,0.75,-1.14,1.237,,46.59,PAH,-1.152,0.168804,0.00158066,0.482998 beta-lactamase_2500_G141C,beta-lactamase_2500_141,TEM-1,beta-lactamase_2500,P62593,0.483002,NO,141,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.828,-5.167,4.339,,0.575,T,l,0.29,-0.28,1.493,,64.69,HOO,-1.08933,0.361275,0.0012419,0.483002 kka2_1:8_E230P,kka2_1:8_230,Kka2,kka2_1:8,P00552,0.483079,NO,230,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.672,-4.133,1.461,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.100394,0.00920051,0.483079 kka2_1:8_E230P,kka2_1:8_230,Kka2,kka2_1:8,P00552,0.483079,NO,230,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.672,-4.133,1.461,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.100394,0.00920051,0.483079 kka2_1:4_D183P,kka2_1:4_183,Kka2,kka2_1:4,P00552,0.483085,NO,183,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.204,-3.861,2.657,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.168804,0.00426304,0.483085 kka2_1:2_R66E,kka2_1:2_66,Kka2,kka2_1:2,P00552,0.483117,NO,66,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-0.922,-3.242,2.32,,0.103,H,A,1.2,-0.2,2.659,,46.21,HBH,-1.13567,0.295029,0.00161025,0.483117 beta-lactamase_2500_L89G,beta-lactamase_2500_89,TEM-1,beta-lactamase_2500,P62593,0.483128,NO,89,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.096,-3.653,2.557,,0.168,T,A,0.55,0.63,2.066,,64.34,PHO,-1.75767,0.361275,0.00207068,0.483128 kka2_1:2_G95Y,kka2_1:2_95,Kka2,kka2_1:2,P00552,0.4832,NO,95,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-2.403,-4.397,1.994,,0.126,E,B,0.29,-0.74,0.359,,71.59,HOA,-2.198,0.295029,0.00743616,0.4832 beta-lactamase_2500_N130C,beta-lactamase_2500_130,TEM-1,beta-lactamase_2500,P62593,0.483228,NO,130,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-0.798,-5.087,4.289,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.361275,0.000683376,0.483228 beta-lactamase_2500_Y103M,beta-lactamase_2500_103,TEM-1,beta-lactamase_2500,P62593,0.483239,NO,103,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-1.33,-4.627,3.297,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.361275,0.00443048,0.483239 beta-lactamase_2500_L47S,beta-lactamase_2500_47,TEM-1,beta-lactamase_2500,P62593,0.483261,NO,47,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.876,-3.642,1.766,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.361275,0.00439844,0.483261 beta-lactamase_M115N,beta-lactamase_115,TEM-1,beta-lactamase,P62593,0.483348,NO,115,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.389,-4.013,2.624,4.89743,0.019,E,B,1.3,0.08,1.236,,69.58,OHP,-1.25433,0.221079,0.0034337,0.483348 kka2_1:4_E96F,kka2_1:4_96,Kka2,kka2_1:4,P00552,0.483407,NO,96,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.573,-4.257,1.684,,0.476,,B,1.52,-0.65,1.254,,71.59,OAH,-2.143,0.168804,0.00369441,0.483407 kka2_1:8_L123S,kka2_1:8_123,Kka2,kka2_1:8,P00552,0.483441,NO,123,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.888,-3.661,2.773,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.100394,0.00325188,0.483441 kka2_1:8_L123S,kka2_1:8_123,Kka2,kka2_1:8,P00552,0.483441,NO,123,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.888,-3.661,2.773,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.100394,0.00325188,0.483441 kka2_1:1_D82N,kka2_1:1_82,Kka2,kka2_1:1,P00552,0.483608,NO,82,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.946,-3.098,1.152,,0.341,E,b,0.75,0.52,11.345,11.345,63.64,HAH,-1.98,0.520039,0.00637516,0.483608 kka2_1:1_G88R,kka2_1:1_88,Kka2,kka2_1:1,P00552,0.483625,NO,88,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.689,-3.209,1.52,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.520039,0.00685559,0.483625 beta-lactamase_39_G243D,beta-lactamase_39_243,TEM-1,beta-lactamase_39,P62593,0.48366,NO,243,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.0495842,0.00464034,0.48366 kka2_1:8_L223D,kka2_1:8_223,Kka2,kka2_1:8,P00552,0.483692,NO,223,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.861,-4.172,3.311,,,H,A,1.59,-1.24,1.017,,50,HHH,-0.854333,0.100394,0.00253574,0.483692 kka2_1:8_L223D,kka2_1:8_223,Kka2,kka2_1:8,P00552,0.483692,NO,223,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.861,-4.172,3.311,,,H,A,1.59,-1.24,1.017,,50,HHH,-0.854333,0.100394,0.00253574,0.483692 beta-lactamase_A235E,beta-lactamase_235,TEM-1,beta-lactamase,P62593,0.483735,NO,235,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.266,-3.558,2.292,4.83024,0.32,E,B,0.52,-0.86,1.344,,50,OHO,-0.89,0.221079,0.00493474,0.483735 beta-lactamase_39_S233I,beta-lactamase_39_233,TEM-1,beta-lactamase_39,P62593,0.483747,NO,233,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.886,-3.784,1.898,,0.016,E,B,0.27,-1.01,5.361,,77.62,BPO,-1.17267,0.0495842,0.00311415,0.483747 beta-lactamase_0_G39I,beta-lactamase_0_39,TEM-1,beta-lactamase_0,P62593,0.483765,NO,39,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.864,-4.195,2.331,,0.701,T,L,0.29,0.47,4.111,,77.62,HOH,-1.53633,0.0500837,0.00487611,0.483765 beta-lactamase_T69A,beta-lactamase_69,TEM-1,beta-lactamase,P62593,0.48383,NO,69,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-0.973,-2.115,1.142,5.16042,,G,A,0.69,-1.24,0.505,,93.01,PPH,-1.01833,0.221079,0.00127498,0.48383 kka2_1:2_D154E,kka2_1:2_154,Kka2,kka2_1:2,P00552,0.483852,NO,154,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.876,-2.369,1.493,,0.457,,b,0.29,1.48,3.631,,52.65,HAP,-1.52467,0.295029,0.00292633,0.483852 kka2_1:8_A224K,kka2_1:8_224,Kka2,kka2_1:8,P00552,0.483857,NO,224,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.977,-3.586,2.609,,,H,A,0.46,-1.26,0.357,,63.64,HHP,-1.41033,0.100394,0.00352047,0.483857 kka2_1:8_A224K,kka2_1:8_224,Kka2,kka2_1:8,P00552,0.483857,NO,224,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.977,-3.586,2.609,,,H,A,0.46,-1.26,0.357,,63.64,HHP,-1.41033,0.100394,0.00352047,0.483857 Ubiquitin_F4T,Ubiquitin_4,Uba1,Ubiquitin,P0CG48,0.483871,NO,4,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.534,-3.532,1.998,4.77459,0.059,E,B,,-0.46,,,,HHH,-1.504,0.205827,0.000805043,0.483871 Ubiquitin_I36S,Ubiquitin_36,Uba1,Ubiquitin,P0CG48,0.483871,NO,36,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.477,-2.402,0.925,5.1035,0.203,,B,0.27,-0.22,1.552,,30.8,OHO,-1.30767,0.205827,0.000630555,0.483871 Ubiquitin_K11D,Ubiquitin_11,Uba1,Ubiquitin,P0CG48,0.483871,NO,11,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.354,-3.43,2.076,5.16813,0.401,,B,2.81,0.84,0.335,,25.84,OBP,-1.346,0.205827,0.000535553,0.483871 Ubiquitin_L67H,Ubiquitin_67,Uba1,Ubiquitin,P0CG48,0.483871,NO,67,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.435,-3.203,1.768,4.92156,,E,B,1.19,-1.02,6.371,6.371,30.8,PHB,-1.628,0.205827,0.000482727,0.483871 Ubiquitin_V70A,Ubiquitin_70,Uba1,Ubiquitin,P0CG48,0.483871,NO,70,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.874,-2.486,0.612,5.29728,0.05,E,B,0.96,-0.97,2.363,,34.31,HHH,-1.65533,0.205827,0.00106871,0.483871 Ubiquitin_Y59E,Ubiquitin_59,Uba1,Ubiquitin,P0CG48,0.483871,NO,59,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-1.307,-3.667,2.36,5.05599,0.072,G,A,0.43,-0.74,2.566,,24.53,AHP,-1.568,0.205827,0.000775084,0.483871 kka2_1:2_L174R,kka2_1:2_174,Kka2,kka2_1:2,P00552,0.483872,NO,174,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.952,-4.019,3.067,,,H,A,1.59,-0.31,8.521,,51.89,BHB,-2.08533,0.295029,0.00438501,0.483872 beta-lactamase_2500_D48C,beta-lactamase_2500_48,TEM-1,beta-lactamase_2500,P62593,0.483875,NO,48,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.101,-5.125,4.024,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.361275,0.0027273,0.483875 beta-lactamase_156_G142V,beta-lactamase_156_142,TEM-1,beta-lactamase_156,P62593,0.483895,NO,142,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.707,-3.751,3.044,,0.034,,p,0.29,-0.64,0.325,,64.69,OOO,-0.834,0.111618,0.00060149,0.483895 kka2_1:1_E230V,kka2_1:1_230,Kka2,kka2_1:1,P00552,0.483911,NO,230,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.672,-3.108,0.436,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.520039,0.00920051,0.483911 kka2_1:2_G30H,kka2_1:2_30,Kka2,kka2_1:2,P00552,0.483981,NO,30,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.596,-4.708,4.112,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.295029,0.00159208,0.483981 kka2_1:8_D220P,kka2_1:8_220,Kka2,kka2_1:8,P00552,0.484083,NO,220,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.787,-3.727,2.94,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.100394,0.00158066,0.484083 kka2_1:8_D220P,kka2_1:8_220,Kka2,kka2_1:8,P00552,0.484083,NO,220,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.787,-3.727,2.94,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.100394,0.00158066,0.484083 kka2_1:8_D220S,kka2_1:8_220,Kka2,kka2_1:8,P00552,0.484083,NO,220,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.787,-3.25,2.463,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.100394,0.00158066,0.484083 kka2_1:8_D220S,kka2_1:8_220,Kka2,kka2_1:8,P00552,0.484083,NO,220,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.787,-3.25,2.463,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.100394,0.00158066,0.484083 kka2_1:2_E111W,kka2_1:2_111,Kka2,kka2_1:2,P00552,0.484201,NO,111,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.28,-5.588,3.308,,0.155,H,A,1.52,-1.14,2.792,,65.53,HAB,-2.27833,0.295029,0.00746789,0.484201 beta-lactamase_2500_D83T,beta-lactamase_2500_83,TEM-1,beta-lactamase_2500,P62593,0.484226,NO,83,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.066,-3.464,2.398,,0.354,H,A,0.75,0.22,0.239,,48.95,HAH,-1.34733,0.361275,0.00205968,0.484226 beta-lactamase_625_T131W,beta-lactamase_625_131,TEM-1,beta-lactamase_625,P62593,0.484227,NO,131,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.328,-5.315,3.987,,,H,A,0.22,-0.69,2.031,,67.48,PPH,-1.00867,0.213352,0.00345886,0.484227 kka2_1:2_V36T,kka2_1:2_36,Kka2,kka2_1:2,P00552,0.484329,NO,36,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-0.898,-3.307,2.409,,0.292,E,B,1.48,0.21,1.064,,52.27,HHH,-1.484,0.295029,0.00245633,0.484329 beta-lactamase_2500_E210P,beta-lactamase_2500_210,TEM-1,beta-lactamase_2500,P62593,0.484348,NO,210,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.319,-4.023,1.704,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.361275,0.00663582,0.484348 PSD95pdz3_G330H,PSD95pdz3_330,PSD95pdz3,PSD95pdz3,P31016,0.484374,NO,330,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.008,-4.362,3.354,4.68351,,,,,31.405,,,,OOA,-1.14,0.0758425,0.000962386,0.484374 kka2_1:2_D159P,kka2_1:2_159,Kka2,kka2_1:2,P00552,0.484419,NO,159,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.82,-3.747,2.927,,0.28,.,B,0.75,1.25,0.899,,48.11,HAA,-1.48333,0.295029,0.0030485,0.484419 beta-lactamase_625_Y95C,beta-lactamase_625_95,TEM-1,beta-lactamase_625,P62593,0.484454,NO,95,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-1.715,-4.95,3.235,,0.122,,b,0.21,-0.37,3.355,,77.62,BHP,-2.16167,0.213352,0.00479449,0.484454 kka2_1:4_D157K,kka2_1:4_157,Kka2,kka2_1:4,P00552,0.484487,NO,157,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.993,-3.506,2.513,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.168804,0.0042313,0.484487 beta-lactamase_156_G142L,beta-lactamase_156_142,TEM-1,beta-lactamase_156,P62593,0.484521,NO,142,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.707,-3.771,3.064,,0.034,,p,0.29,-0.64,0.325,,64.69,OOO,-0.834,0.111618,0.00060149,0.484521 kka2_1:2_Q136D,kka2_1:2_136,Kka2,kka2_1:2,P00552,0.484532,NO,136,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-3.021,-3.719,0.698,,0.331,,b,0.4,0.96,2.726,,92.05,BPH,-2.16933,0.295029,0.00624149,0.484532 beta-lactamase_2500_L47E,beta-lactamase_2500_47,TEM-1,beta-lactamase_2500,P62593,0.484541,NO,47,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.876,-2.999,1.123,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.361275,0.00439844,0.484541 kka2_1:2_L184K,kka2_1:2_184,Kka2,kka2_1:2,P00552,0.484565,NO,184,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.496,-2.828,1.332,,0.489,E,B,0.55,-0.06,14.044,14.044,63.26,AHH,-1.24833,0.295029,0.00518742,0.484565 beta-lactamase_2500_D231I,beta-lactamase_2500_231,TEM-1,beta-lactamase_2500,P62593,0.484613,NO,231,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.816,-4.036,3.22,,,E,B,0.75,-1.06,0.319,,65.38,HAB,-0.994,0.361275,0.00107395,0.484613 beta-lactamase_39_K232N,beta-lactamase_39_232,TEM-1,beta-lactamase_39,P62593,0.484646,NO,232,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.012,-3.49,2.478,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.0495842,0.00313441,0.484646 beta-lactamase_2500_H110V,beta-lactamase_2500_110,TEM-1,beta-lactamase_2500,P62593,0.484681,NO,110,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-1.706,-3.735,2.029,,0.341,G,a,0.17,1.08,31.31,31.31,64.69,BBH,-1.73333,0.361275,0.00441499,0.484681 beta-lactamase_M209F,beta-lactamase_209,TEM-1,beta-lactamase,P62593,0.484705,NO,209,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.442,-2.51,1.068,5.44502,,H,A,1.75,-0.97,1.402,,64.69,HHA,-1.52633,0.221079,0.00625021,0.484705 hsp90_G584H,hsp90_584,hsp90,hsp90,P02829,0.484738,NO,584,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-2.511,-3.833,0,5.20094,0.414,S,b,0.84,0.33,,,,HOH,-3.32733,0.368192,0.000222939,0.484738 beta-lactamase_39_F64S,beta-lactamase_39_64,TEM-1,beta-lactamase_39,P62593,0.484796,NO,64,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-0.841,-3.611,2.77,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.0495842,0.000947691,0.484796 beta-lactamase_2500_L191A,beta-lactamase_2500_191,TEM-1,beta-lactamase_2500,P62593,0.484977,NO,191,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.087,-2.236,1.149,,,H,A,0.55,0.09,1.703,,63.29,BHH,-1.445,0.361275,0.00263549,0.484977 beta-lactamase_2500_G236T,beta-lactamase_2500_236,TEM-1,beta-lactamase_2500,P62593,0.48498,NO,236,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.784,-3.55,2.766,,0.241,,b,0.29,-0.59,2.14,,64.69,HOO,-1.025,0.361275,0.00162372,0.48498 kka2_1:4_D208G,kka2_1:4_208,Kka2,kka2_1:4,P00552,0.48498,NO,208,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.708,-3.161,2.453,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.168804,0.00212588,0.48498 Pab1_K131Q,Pab1_131,Pab1,Pab1,P04147,0.485003,NO,131,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.083,-3.266,2.183,,0.462,E,B,1.82,0.57,,,,HBP,-1.12467,0.175299,0.000349395,0.485003 beta-lactamase_156_G236I,beta-lactamase_156_236,TEM-1,beta-lactamase_156,P62593,0.485065,NO,236,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.784,-4.139,3.355,,0.241,,b,0.29,-0.59,1.883,,64.69,HOO,-1.025,0.111618,0.00162372,0.485065 kka2_1:2_A110T,kka2_1:2_110,Kka2,kka2_1:2,P00552,0.485132,NO,110,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.064,-3.141,1.077,,0.175,H,A,0.46,-1.19,23.237,23.237,71.59,OHA,-1.91867,0.295029,0.00759851,0.485132 kka2_1:2_K50S,kka2_1:2_50,Kka2,kka2_1:2,P00552,0.485132,NO,50,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-0.833,-3.233,2.4,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.295029,0.00138626,0.485132 kka2_1:8_L102Q,kka2_1:8_102,Kka2,kka2_1:8,P00552,0.48523,NO,102,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.804,-4.12,3.316,,,T,A,1.59,-1.17,0.97,,42.42,AHH,-1.398,0.100394,0.00201332,0.48523 kka2_1:8_L102Q,kka2_1:8_102,Kka2,kka2_1:8,P00552,0.48523,NO,102,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.804,-4.12,3.316,,,T,A,1.59,-1.17,0.97,,42.42,AHH,-1.398,0.100394,0.00201332,0.48523 beta-lactamase_625_D212I,beta-lactamase_625_212,TEM-1,beta-lactamase_625,P62593,0.485391,NO,212,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.624,-3.045,1.421,,0.037,,b,0.75,-0.58,1.516,,74.48,HAB,-1.77667,0.213352,0.00644302,0.485391 kka2_1:8_H135Y,kka2_1:8_135,Kka2,kka2_1:8,P00552,0.485624,NO,135,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-1.331,-3.702,2.371,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.100394,0.00532566,0.485624 kka2_1:8_H135Y,kka2_1:8_135,Kka2,kka2_1:8,P00552,0.485624,NO,135,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-1.331,-3.702,2.371,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.100394,0.00532566,0.485624 beta-lactamase_2500_G52L,beta-lactamase_2500_52,TEM-1,beta-lactamase_2500,P62593,0.485856,NO,52,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.149,-3.755,2.606,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.361275,0.00340138,0.485856 kka2_1:8_D118P,kka2_1:8_118,Kka2,kka2_1:8,P00552,0.485884,NO,118,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.07,-4.037,1.967,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.100394,0.0067852,0.485884 kka2_1:8_D118P,kka2_1:8_118,Kka2,kka2_1:8,P00552,0.485884,NO,118,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.07,-4.037,1.967,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.100394,0.0067852,0.485884 kka2_1:8_K50I,kka2_1:8_50,Kka2,kka2_1:8,P00552,0.485939,NO,50,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-0.833,-4.062,3.229,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.100394,0.00138626,0.485939 kka2_1:8_K50I,kka2_1:8_50,Kka2,kka2_1:8,P00552,0.485939,NO,50,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-0.833,-4.062,3.229,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.100394,0.00138626,0.485939 beta-lactamase_2500_Y44I,beta-lactamase_2500_44,TEM-1,beta-lactamase_2500,P62593,0.485945,NO,44,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-2.547,-2.364,-0.183,,,E,B,0.21,-0.45,2.184,,73.78,OHH,-1.86267,0.361275,0.00426364,0.485945 kka2_1:1_V84S,kka2_1:1_84,Kka2,kka2_1:1,P00552,0.486005,NO,84,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-2.279,-2.917,0.638,,0.258,E,B,0.44,1.03,3.484,,71.59,HHP,-2.337,0.520039,0.00724019,0.486005 gb1_Y271S,gb1_271,gb1,gb1,P06654,0.48602,NO,271,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-1.181,-3.388,2.207,,,,,,,,,,PHA,-1.92933,0.177985,0.00236544,0.48602 beta-lactamase_156_E35F,beta-lactamase_156_35,TEM-1,beta-lactamase_156,P62593,0.486025,NO,35,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-0.869,-4.318,3.449,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.111618,0.00174441,0.486025 kka2_1:4_L107T,kka2_1:4_107,Kka2,kka2_1:4,P00552,0.486031,NO,107,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.238,-2.585,1.347,,0.197,.,B,0.55,-1.1,0.398,,71.59,BHH,-2.143,0.168804,0.00561937,0.486031 kka2_1:2_I254G,kka2_1:2_254,Kka2,kka2_1:2,P00552,0.486172,NO,254,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.933,-3.809,1.876,,0.135,H,A,1.52,-0.6,2.562,,71.59,BHH,-1.668,0.295029,0.0132375,0.486172 kka2_1:1_G233R,kka2_1:1_233,Kka2,kka2_1:1,P00552,0.486183,NO,233,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.748,-4.006,3.258,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.520039,0.00232366,0.486183 beta-lactamase_D48F,beta-lactamase_48,TEM-1,beta-lactamase,P62593,0.486271,NO,48,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.101,-4.285,3.184,4.89966,0.189,E,B,0.23,0.21,1.281,,50.35,HAH,-1.62467,0.221079,0.0027273,0.486271 beta-lactamase_Y44C,beta-lactamase_44,TEM-1,beta-lactamase,P62593,0.486299,NO,44,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-2.547,-4.829,2.282,5.6273,,E,B,2.55,-0.45,2.683,,73.78,OHH,-1.86267,0.221079,0.00426364,0.486299 kka2_1:2_L212P,kka2_1:2_212,Kka2,kka2_1:2,P00552,0.486308,NO,212,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.904,-4.095,3.191,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.295029,0.0031426,0.486308 kka2_1:1_H139I,kka2_1:1_139,Kka2,kka2_1:1,P00552,0.486312,NO,139,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-2.809,-3.326,0.517,,0.471,H,A,0.17,0.68,1.153,,63.64,BBB,-2.22,0.520039,0.00734779,0.486312 beta-lactamase_625_I45E,beta-lactamase_625_45,TEM-1,beta-lactamase_625,P62593,0.486327,NO,45,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-2.421,-3.737,1.316,,,E,B,0.48,-0.3,3.642,,77.62,HHA,-2.30267,0.213352,0.00452842,0.486327 WW_domain_H192C,WW_domain_192,Yap65,WW_domain,P46937,0.486433,NO,192,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-1.739,-4.876,3.137,5.20314,,,,,,1.458,,78.57,PBH,-1.75033,0.153962,0.00436368,0.486433 kka2_1:1_A129T,kka2_1:1_129,Kka2,kka2_1:1,P00552,0.486526,NO,129,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.656,-2.639,0.983,,0.845,G,A,0.46,0.72,19.686,19.686,92.05,OHP,-1.99,0.520039,0.00726862,0.486526 beta-lactamase_2500_E119R,beta-lactamase_2500_119,TEM-1,beta-lactamase_2500,P62593,0.486528,NO,119,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.412,-3.743,2.331,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.361275,0.00386966,0.486528 beta-lactamase_625_D231V,beta-lactamase_625_231,TEM-1,beta-lactamase_625,P62593,0.48653,NO,231,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.816,-3.751,2.935,,,E,B,0.75,-1.06,1.025,,65.38,HAB,-0.994,0.213352,0.00107395,0.48653 kka2_1:2_I221Q,kka2_1:2_221,Kka2,kka2_1:2,P00552,0.486641,NO,221,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.739,-4.324,2.585,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.295029,0.00945908,0.486641 beta-lactamase_S240Y,beta-lactamase_240,TEM-1,beta-lactamase,P62593,0.486701,NO,240,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.537,-4.296,2.759,4.75024,,,B,0.74,-0.74,0.357,,65.38,OPB,-1.263,0.221079,0.00591201,0.486701 beta-lactamase_P143Y,beta-lactamase_143,TEM-1,beta-lactamase,P62593,0.486741,NO,143,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.967,-4.337,3.37,5.16366,0.075,H,A,0.99,-0.37,0.479,,66.78,OOB,-1.354,0.221079,0.00114551,0.486741 beta-lactamase_2500_I140G,beta-lactamase_2500_140,TEM-1,beta-lactamase_2500,P62593,0.48675,NO,140,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.733,-3.828,2.095,,0.128,H,A,0.48,0.41,1.628,,73.08,PHO,-1.48733,0.361275,0.00597777,0.48675 beta-lactamase_2500_R242G,beta-lactamase_2500_242,TEM-1,beta-lactamase_2500,P62593,0.486773,NO,242,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.319,-3.802,2.483,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.361275,0.00452879,0.486773 beta-lactamase_625_V72K,beta-lactamase_625_72,TEM-1,beta-lactamase_625,P62593,0.486792,NO,72,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.658,-3.754,2.096,,,H,A,0.44,-1.03,0.981,,65.73,BHH,-1.32167,0.213352,0.00501194,0.486792 kka2_1:2_A255W,kka2_1:2_255,Kka2,kka2_1:2,P00552,0.486862,NO,255,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.715,-5.451,3.736,,0.466,H,A,0.46,-0.52,5.144,,65.53,HHH,-1.71267,0.295029,0.0126809,0.486862 kka2_1:4_G30D,kka2_1:4_30,Kka2,kka2_1:4,P00552,0.486932,NO,30,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.596,-3.497,2.901,,0.54,S,g,0.29,3.76,,,,HOO,-1.51133,0.168804,0.00159208,0.486932 kka2_1:2_I29S,kka2_1:2_29,Kka2,kka2_1:2,P00552,0.486945,NO,29,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.692,-3.624,1.932,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.295029,0.00619521,0.486945 kka2_1:1_R145Q,kka2_1:1_145,Kka2,kka2_1:1,P00552,0.487,NO,145,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.804,-2.583,0.779,,0.346,H,A,1.2,1.23,23.699,23.699,63.64,HBP,-1.88033,0.520039,0.00846663,0.487 beta-lactamase_156_D48P,beta-lactamase_156_48,TEM-1,beta-lactamase_156,P62593,0.487025,NO,48,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.101,-3.766,2.665,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.111618,0.0027273,0.487025 beta-lactamase_2500_L89W,beta-lactamase_2500_89,TEM-1,beta-lactamase_2500,P62593,0.487031,NO,89,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.096,-5.236,4.14,,0.168,T,A,0.55,0.63,2.066,,64.34,PHO,-1.75767,0.361275,0.00207068,0.487031 beta-lactamase_2500_A247W,beta-lactamase_2500_247,TEM-1,beta-lactamase_2500,P62593,0.487038,NO,247,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.361275,0.00611275,0.487038 beta-lactamase_2500_L150S,beta-lactamase_2500_150,TEM-1,beta-lactamase_2500,P62593,0.487042,NO,150,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.326,-3.477,2.151,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.361275,0.00463171,0.487042 beta-lactamase_625_G52V,beta-lactamase_625_52,TEM-1,beta-lactamase_625,P62593,0.487084,NO,52,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.149,-3.738,2.589,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.213352,0.00340138,0.487084 beta-lactamase_T69M,beta-lactamase_69,TEM-1,beta-lactamase,P62593,0.487148,NO,69,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-0.973,-4.54,3.567,5.16042,,G,A,0.69,-1.24,0.505,,93.01,PPH,-1.01833,0.221079,0.00127498,0.487148 kka2_1:8_D227I,kka2_1:8_227,Kka2,kka2_1:8,P00552,0.487273,NO,227,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.758,-3.917,2.159,,0.128,H,A,0.75,-0.63,0.281,,56.06,BAH,-1.43067,0.100394,0.00745029,0.487273 kka2_1:8_D227I,kka2_1:8_227,Kka2,kka2_1:8,P00552,0.487273,NO,227,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.758,-3.917,2.159,,0.128,H,A,0.75,-0.63,0.281,,56.06,BAH,-1.43067,0.100394,0.00745029,0.487273 beta-lactamase_K284P,beta-lactamase_284,TEM-1,beta-lactamase,P62593,0.487275,NO,284,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.981,-3.803,1.822,6.30084,0.848,H,A,1.82,0.67,1.931,,77.62,HBB,-1.82133,0.221079,0.0686156,0.487275 kka2_1:4_L126G,kka2_1:4_126,Kka2,kka2_1:4,P00552,0.487277,NO,126,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.246,-3.853,2.607,,0.285,S,B,0.55,0.12,0.302,,51.89,PHA,-1.744,0.168804,0.0066485,0.487277 kka2_1:1_A78Q,kka2_1:1_78,Kka2,kka2_1:1,P00552,0.487324,NO,78,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.744,-3.972,2.228,,0.078,.,B,0.46,-0.53,0.206,,56.06,OHH,-1.863,0.520039,0.00457299,0.487324 kka2_1:1_D227V,kka2_1:1_227,Kka2,kka2_1:1,P00552,0.48735,NO,227,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.758,-3.661,1.903,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.520039,0.00745029,0.48735 beta-lactamase_156_N274Y,beta-lactamase_156_274,TEM-1,beta-lactamase_156,P62593,0.48738,NO,274,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.111618,0.0110418,0.48738 kka2_1:1_G164D,kka2_1:1_164,Kka2,kka2_1:1,P00552,0.48739,NO,164,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.869,-2.664,1.795,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.520039,0.00442091,0.48739 kka2_1:1_C77V,kka2_1:1_77,Kka2,kka2_1:1,P00552,0.487405,NO,77,C,V,CV,Special,Hydrophobic,5.07,5.60847,0.538465,192,121,117,-4,108.5,140,31.5,-1.477,-2.554,1.077,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.520039,0.00441216,0.487405 kka2_1:1_E262K,kka2_1:1_262,Kka2,kka2_1:1,P00552,0.487484,NO,262,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-0.829,-3.058,2.229,,0.059,G,A,1.04,-0.18,0.837,,42.42,AAH,-0.816,0.520039,0.0191586,0.487484 beta-lactamase_2500_T264G,beta-lactamase_2500_264,TEM-1,beta-lactamase_2500,P62593,0.48757,NO,264,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.361275,0.0119399,0.48757 beta-lactamase_2500_L135A,beta-lactamase_2500_135,TEM-1,beta-lactamase_2500,P62593,0.487641,NO,135,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.002,-3.131,2.129,,0.117,H,A,0.55,-0.58,0.795,,43.71,PHH,-1.03767,0.361275,0.00244423,0.487641 kka2_1:1_C192T,kka2_1:1_192,Kka2,kka2_1:1,P00552,0.487674,NO,192,C,T,CT,Special,Polar,5.07,5.6,0.53,149,121,119,-2,108.5,116.1,7.6,-1.067,-2.666,1.599,,0.095,.,B,0.46,-0.75,2.749,,50,HOH,-0.960333,0.520039,0.00485428,0.487674 kka2_1:1_A248P,kka2_1:1_248,Kka2,kka2_1:1,P00552,0.4877,NO,248,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.124,-3.022,0.898,,0.825,S,b,0.46,0.46,24.72,24.72,92.05,HHO,-2.15,0.520039,0.0125484,0.4877 beta-lactamase_156_M66N,beta-lactamase_156_66,TEM-1,beta-lactamase_156,P62593,0.487705,NO,66,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.362,-4.083,2.721,,0.013,,A,0.55,-0.7,1.94,,73.08,OHH,-1.49567,0.111618,0.00412876,0.487705 kka2_1:4_C192M,kka2_1:4_192,Kka2,kka2_1:4,P00552,0.487764,NO,192,C,M,CM,Special,Hydrophobic,5.07,5.74,0.67,196,121,149,28,108.5,162.9,54.4,-1.067,-4.582,3.515,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.168804,0.00485428,0.487764 beta-lactamase_2500_L49C,beta-lactamase_2500_49,TEM-1,beta-lactamase_2500,P62593,0.487786,NO,49,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.897,-4.929,3.032,,0.131,T,A,0.55,0.04,6.681,,64.69,AHP,-1.99233,0.361275,0.00401477,0.487786 kka2_1:4_R258M,kka2_1:4_258,Kka2,kka2_1:4,P00552,0.487789,NO,258,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.626,-3.325,1.699,,0.316,H,A,1.2,-0.85,2.655,,53.03,HBH,-1.25933,0.168804,0.00983174,0.487789 kka2_1:2_P132G,kka2_1:2_132,Kka2,kka2_1:2,P00552,0.487817,NO,132,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.775,-3.354,2.579,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.295029,0.0018489,0.487817 kka2_1:8_R258E,kka2_1:8_258,Kka2,kka2_1:8,P00552,0.48782,NO,258,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.626,-2.838,1.212,,0.316,H,A,0.16,-0.85,5.58,,53.03,HBH,-1.25933,0.100394,0.00983174,0.48782 kka2_1:8_R258E,kka2_1:8_258,Kka2,kka2_1:8,P00552,0.48782,NO,258,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.626,-2.838,1.212,,0.316,H,A,0.16,-0.85,5.58,,53.03,HBH,-1.25933,0.100394,0.00983174,0.48782 kka2_1:8_Y257D,kka2_1:8_257,Kka2,kka2_1:8,P00552,0.48782,NO,257,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-1.064,-4.006,2.942,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.100394,0.0148191,0.48782 kka2_1:8_Y257D,kka2_1:8_257,Kka2,kka2_1:8,P00552,0.48782,NO,257,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-1.064,-4.006,2.942,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.100394,0.0148191,0.48782 beta-lactamase_156_S201E,beta-lactamase_156_201,TEM-1,beta-lactamase_156,P62593,0.487872,NO,201,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.183,-3.352,2.169,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.111618,0.00198815,0.487872 kka2_1:2_H124K,kka2_1:2_124,Kka2,kka2_1:2,P00552,0.487931,NO,124,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-0.84,-3.485,2.645,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.295029,0.00211296,0.487931 beta-lactamase_2500_G216I,beta-lactamase_2500_216,TEM-1,beta-lactamase_2500,P62593,0.487938,NO,216,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.477,-4.183,2.706,,0.437,I,A,0.29,-0.58,1.983,,74.48,HOO,-1.68067,0.361275,0.00639568,0.487938 beta-lactamase_2500_G281L,beta-lactamase_2500_281,TEM-1,beta-lactamase_2500,P62593,0.487945,NO,281,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.361275,0.0406482,0.487945 E1_Ubiquitin_R72G,E1_Ubiquitin_72,Uba1,E1_Ubiquitin,P0CG63,0.488064,NO,72,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.184,-3.175,1.991,,0.077,,B,0.16,-0.1,,,,HBH,-1.08733,0.18783,0.00129853,0.488064 kka2_1:2_H135I,kka2_1:2_135,Kka2,kka2_1:2,P00552,0.488171,NO,135,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-1.331,-3.976,2.645,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.295029,0.00532566,0.488171 beta-lactamase_156_V78K,beta-lactamase_156_78,TEM-1,beta-lactamase_156,P62593,0.488174,NO,78,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.459,-3.849,2.39,,,H,A,0.44,-0.47,1.132,,63.64,HHH,-1.17833,0.111618,0.00492501,0.488174 beta-lactamase_2500_L197S,beta-lactamase_2500_197,TEM-1,beta-lactamase_2500,P62593,0.488186,NO,197,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.853,-3.532,2.679,,0.007,S,B,0.55,0.33,2.421,,60.14,HHP,-1.833,0.361275,0.00144602,0.488186 beta-lactamase_2500_A215I,beta-lactamase_2500_215,TEM-1,beta-lactamase_2500,P62593,0.488319,NO,215,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.503,-3.916,2.413,,,,a,0.46,-0.93,3.516,,74.48,HHO,-1.42633,0.361275,0.00544007,0.488319 WW_domain_Q195L,WW_domain_195,Yap65,WW_domain,P46937,0.488325,NO,195,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-1.839,-3.146,1.307,5.22735,,,,,,1.803,,70.04,APP,-1.719,0.153962,0.00394344,0.488325 kka2_1:2_R226T,kka2_1:2_226,Kka2,kka2_1:2,P00552,0.488408,NO,226,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.392,-3.626,2.234,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.295029,0.0108032,0.488408 kka2_1:1_D118T,kka2_1:1_118,Kka2,kka2_1:1,P00552,0.488609,NO,118,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.07,-2.449,0.379,,0.61,H,A,0.75,-0.05,13.434,13.434,64.39,HAH,-1.32367,0.520039,0.0067852,0.488609 kka2_1:4_C131V,kka2_1:4_131,Kka2,kka2_1:4,P00552,0.488629,NO,131,C,V,CV,Special,Hydrophobic,5.07,5.60847,0.538465,192,121,117,-4,108.5,140,31.5,-0.831,-3.332,2.501,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.168804,0.00170814,0.488629 kka2_1:2_Y257D,kka2_1:2_257,Kka2,kka2_1:2,P00552,0.48866,NO,257,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-1.064,-4.006,2.942,,0.022,H,A,0.21,-0.88,0.833,,52.65,HHB,-1.39333,0.295029,0.0148191,0.48866 kka2_1:2_L60A,kka2_1:2_60,Kka2,kka2_1:2,P00552,0.488677,NO,60,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.997,-3.185,2.188,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.295029,0.00262176,0.488677 kka2_1:1_T125K,kka2_1:1_125,Kka2,kka2_1:1,P00552,0.488682,NO,125,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.622,-2.941,0.319,,0.791,T,A,0.22,0.33,1.972,,92.05,BPH,-1.56933,0.520039,0.00821755,0.488682 beta-lactamase_2500_G52T,beta-lactamase_2500_52,TEM-1,beta-lactamase_2500,P62593,0.488691,NO,52,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.149,-3.586,2.437,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.361275,0.00340138,0.488691 kka2_1:1_G245T,kka2_1:1_245,Kka2,kka2_1:1,P00552,0.488706,NO,245,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.812,-3.629,2.817,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.520039,0.00683899,0.488706 beta-lactamase_625_A40H,beta-lactamase_625_40,TEM-1,beta-lactamase_625,P62593,0.488726,NO,40,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.402,-4.792,3.39,,0.155,S,B,0.46,0.21,1.357,,73.78,OHB,-1.40267,0.213352,0.00490026,0.488726 kka2_1:1_S68C,kka2_1:1_68,Kka2,kka2_1:1,P00552,0.488766,NO,68,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.623,-3.588,0.965,,0.48,H,A,0.27,-0.1,2.655,,71.59,HPH,-1.40767,0.520039,0.00608265,0.488766 beta-lactamase_39_T107R,beta-lactamase_39_107,TEM-1,beta-lactamase_39,P62593,0.488783,NO,107,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.117,-3.76,2.643,,,G,A,0.22,-0.06,2.686,,67.83,HPA,-1.265,0.0495842,0.00239347,0.488783 beta-lactamase_2500_I244T,beta-lactamase_2500_244,TEM-1,beta-lactamase_2500,P62593,0.488856,NO,244,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.555,-2.572,1.017,,,E,B,0.48,-0.84,1.683,,77.62,OHH,-1.385,0.361275,0.00605379,0.488856 kka2_1:2_L67S,kka2_1:2_67,Kka2,kka2_1:2,P00552,0.488897,NO,67,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.741,-3.639,2.898,,0.007,H,A,1.59,-0.66,,,,BHP,-1.42867,0.295029,0.00102787,0.488897 kka2_1:1_I254T,kka2_1:1_254,Kka2,kka2_1:1,P00552,0.488907,NO,254,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.933,-3.596,1.663,,0.135,H,A,1.52,-0.6,1.859,,71.59,BHH,-1.668,0.520039,0.0132375,0.488907 beta-lactamase_2500_Y44V,beta-lactamase_2500_44,TEM-1,beta-lactamase_2500,P62593,0.489077,NO,44,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-2.547,-1.805,-0.742,,,E,B,0.21,-0.45,2.184,,73.78,OHH,-1.86267,0.361275,0.00426364,0.489077 kka2_1:2_G245T,kka2_1:2_245,Kka2,kka2_1:2,P00552,0.489101,NO,245,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.812,-3.629,2.817,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.295029,0.00683899,0.489101 kka2_1:4_L241K,kka2_1:4_241,Kka2,kka2_1:4,P00552,0.489118,NO,241,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.158,-3.87,2.712,,0.08,H,A,0.55,-0.82,1.598,,63.26,HHH,-1.58533,0.168804,0.0117299,0.489118 beta-lactamase_2500_A235V,beta-lactamase_2500_235,TEM-1,beta-lactamase_2500,P62593,0.489144,NO,235,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.266,-2.665,1.399,,0.32,E,B,0.46,-0.86,0.891,,50,OHO,-0.89,0.361275,0.00493474,0.489144 kka2_1:1_L126V,kka2_1:1_126,Kka2,kka2_1:1,P00552,0.489179,NO,126,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.246,-1.955,0.709,,0.285,S,B,0.55,0.12,0.302,,51.89,PHA,-1.744,0.520039,0.0066485,0.489179 kka2_1:1_D127E,kka2_1:1_127,Kka2,kka2_1:1,P00552,0.489182,NO,127,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.364,-2.659,1.295,,0.573,.,B,0.75,0.45,3.414,,50.38,HAO,-1.51067,0.520039,0.00660501,0.489182 kka2_1:2_S204N,kka2_1:2_204,Kka2,kka2_1:2,P00552,0.489188,NO,204,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.353,-3.559,2.206,,0.144,E,A,0.27,-1.2,2.442,,65.53,HPO,-0.953333,0.295029,0.00881794,0.489188 kka2_1:8_G95W,kka2_1:8_95,Kka2,kka2_1:8,P00552,0.489225,NO,95,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-2.403,-5.488,3.085,,0.126,E,B,0.75,-0.74,7.774,,71.59,HOA,-2.198,0.100394,0.00743616,0.489225 kka2_1:8_G95W,kka2_1:8_95,Kka2,kka2_1:8,P00552,0.489225,NO,95,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-2.403,-5.488,3.085,,0.126,E,B,0.75,-0.74,7.774,,71.59,HOA,-2.198,0.100394,0.00743616,0.489225 kka2_1:1_L212Q,kka2_1:1_212,Kka2,kka2_1:1,P00552,0.489241,NO,212,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.904,-4.175,3.271,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.520039,0.0031426,0.489241 beta-lactamase_L218H,beta-lactamase_218,TEM-1,beta-lactamase,P62593,0.489244,NO,218,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.391,-4.744,3.353,4.88972,,I,b,2.89,-0.53,12.788,12.788,74.48,OHH,-1.58867,0.221079,0.00618274,0.489244 kka2_1:4_K112D,kka2_1:4_112,Kka2,kka2_1:4,P00552,0.489258,NO,112,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-2.491,-3.95,1.459,,0.076,H,A,2.34,-1.37,0.39,,56.06,ABH,-2.00133,0.168804,0.00645389,0.489258 kka2_1:1_R217C,kka2_1:1_217,Kka2,kka2_1:1,P00552,0.489259,NO,217,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.158,-5.113,3.955,,0.252,T,A,1.2,-0.59,0.381,,52.27,ABH,-1.127,0.520039,0.0047191,0.489259 beta-lactamase_2500_D231C,beta-lactamase_2500_231,TEM-1,beta-lactamase_2500,P62593,0.489292,NO,231,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.816,-5.136,4.32,,,E,B,0.75,-1.06,0.319,,65.38,HAB,-0.994,0.361275,0.00107395,0.489292 beta-lactamase_2500_V72E,beta-lactamase_2500_72,TEM-1,beta-lactamase_2500,P62593,0.489324,NO,72,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.658,-3.755,2.097,,,H,A,0.44,-1.03,2.079,,65.73,BHH,-1.32167,0.361275,0.00501194,0.489324 kka2_1:4_A117C,kka2_1:4_117,Kka2,kka2_1:4,P00552,0.489327,NO,117,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.828,-4.504,3.676,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.168804,0.00282984,0.489327 beta-lactamase_2500_L38D,beta-lactamase_2500_38,TEM-1,beta-lactamase_2500,P62593,0.489333,NO,38,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.343,-3.97,2.627,,0.088,H,A,0.55,0.2,2.71,,64.34,PHO,-1.78033,0.361275,0.00373244,0.489333 kka2_1:2_F256V,kka2_1:2_256,Kka2,kka2_1:2,P00552,0.489353,NO,256,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.49,-3.528,2.038,,,H,A,0.58,-0.78,1.653,,53.03,HHH,-1.423,0.295029,0.0132841,0.489353 kka2_1:4_D190R,kka2_1:4_190,Kka2,kka2_1:4,P00552,0.489366,NO,190,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.708,-3.961,3.253,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.168804,0.00247989,0.489366 kka2_1:1_I29F,kka2_1:1_29,Kka2,kka2_1:1,P00552,0.489419,NO,29,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.692,-4.042,2.35,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.520039,0.00619521,0.489419 beta-lactamase_0_S68N,beta-lactamase_0_68,TEM-1,beta-lactamase_0,P62593,0.489426,NO,68,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-0.913,-2.44,1.527,,0.064,G,A,0.27,-1.03,1.441,,64.69,HPP,-1.37233,0.0500837,0.000800065,0.489426 kka2_1:1_M178H,kka2_1:1_178,Kka2,kka2_1:1,P00552,0.489496,NO,178,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-3.206,-4.758,1.552,,0.554,.,b,0.55,0.68,3.152,,71.59,BHO,-2.154,0.520039,0.00717253,0.489496 beta-lactamase_2500_R118P,beta-lactamase_2500_118,TEM-1,beta-lactamase_2500,P62593,0.489517,NO,118,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.413,-3.946,1.533,,0.457,H,A,1.2,1.39,2.144,,77.62,HBA,-1.785,0.361275,0.00538794,0.489517 beta-lactamase_G141W,beta-lactamase_141,TEM-1,beta-lactamase,P62593,0.489518,NO,141,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.828,-5.233,4.405,5.03155,0.575,T,l,0.76,-0.28,0.198,,64.69,HOO,-1.08933,0.221079,0.0012419,0.489518 kka2_1:2_G88T,kka2_1:2_88,Kka2,kka2_1:2,P00552,0.489663,NO,88,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.689,-3.065,1.376,,0.54,S,l,0.75,1.51,2.814,,65.53,HOB,-1.718,0.295029,0.00685559,0.489663 beta-lactamase_39_G76E,beta-lactamase_39_76,TEM-1,beta-lactamase_39,P62593,0.489673,NO,76,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.189,-3.614,2.425,,,H,A,0.29,-0.67,2.145,,67.83,OOH,-1.22267,0.0495842,0.00476637,0.489673 beta-lactamase_2500_D161A,beta-lactamase_2500_161,TEM-1,beta-lactamase_2500,P62593,0.489703,NO,161,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.891,-3.235,2.344,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.361275,0.000897697,0.489703 beta-lactamase_2500_G141D,beta-lactamase_2500_141,TEM-1,beta-lactamase_2500,P62593,0.48987,NO,141,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.828,-2.284,1.456,,0.575,T,l,0.29,-0.28,1.493,,64.69,HOO,-1.08933,0.361275,0.0012419,0.48987 gb1_A260L,gb1_260,gb1,gb1,P06654,0.489898,NO,260,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.486,-1.962,0.476,,,,,,,0.173,,9.6,HHP,-1.70967,0.177985,0.0055808,0.489898 beta-lactamase_39_V117D,beta-lactamase_39_117,TEM-1,beta-lactamase_39,P62593,0.489906,NO,117,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.53,-4.116,2.586,,,H,A,0.44,-0.34,1.182,,65.03,PHB,-1.741,0.0495842,0.00467906,0.489906 beta-lactamase_2500_A230V,beta-lactamase_2500_230,TEM-1,beta-lactamase_2500,P62593,0.489953,NO,230,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.154,-3.38,2.226,,0.01,E,B,0.46,-1.17,1.171,,50,HHA,-1.079,0.361275,0.00516841,0.489953 beta-lactamase_625_R242V,beta-lactamase_625_242,TEM-1,beta-lactamase_625,P62593,0.489953,NO,242,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.213352,0.00452879,0.489953 kka2_1:4_E59P,kka2_1:4_59,Kka2,kka2_1:4,P00552,0.490023,NO,59,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-0.952,-3.748,2.796,,0.187,.,L,1.04,0.62,3.408,,50.38,PAH,-1.53,0.168804,0.00280355,0.490023 beta-lactamase_2500_S104T,beta-lactamase_2500_104,TEM-1,beta-lactamase_2500,P62593,0.490056,NO,104,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.015,-3.098,2.083,,0.04,,b,0.27,0.57,1.133,,63.29,HPO,-1.05267,0.361275,0.00218083,0.490056 kka2_1:2_K112I,kka2_1:2_112,Kka2,kka2_1:2,P00552,0.490062,NO,112,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-2.491,-2.233,-0.258,,0.076,H,A,2.34,-1.37,23.433,23.433,56.06,ABH,-2.00133,0.295029,0.00645389,0.490062 kka2_1:2_I115L,kka2_1:2_115,Kka2,kka2_1:2,P00552,0.490078,NO,115,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.606,-1.667,0.061,,0.105,H,A,0.48,-1.18,0.878,,65.53,PHH,-2.205,0.295029,0.00836567,0.490078 beta-lactamase_39_A185E,beta-lactamase_39_185,TEM-1,beta-lactamase_39,P62593,0.490115,NO,185,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.406,-3.679,2.273,,,H,A,0.46,-1.02,2.68,,65.03,HHP,-1.84033,0.0495842,0.00467449,0.490115 beta-lactamase_2500_F149D,beta-lactamase_2500_149,TEM-1,beta-lactamase_2500,P62593,0.490125,NO,149,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.299,-3.957,2.658,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.361275,0.00418462,0.490125 kka2_1:2_E96V,kka2_1:2_96,Kka2,kka2_1:2,P00552,0.490147,NO,96,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.573,-2.716,0.143,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.295029,0.00369441,0.490147 beta-lactamase_2500_L284Q,beta-lactamase_2500_284,TEM-1,beta-lactamase_2500,P62593,0.490282,NO,284,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.361275,0.0686156,0.490282 kka2_1:1_P109R,kka2_1:1_109,Kka2,kka2_1:1,P00552,0.490283,NO,109,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.412,-3.997,2.585,,0.376,H,A,0.52,-1.25,18.506,18.506,65.53,HOH,-1.84567,0.520039,0.0070929,0.490283 kka2_1:8_A229P,kka2_1:8_229,Kka2,kka2_1:8,P00552,0.490313,NO,229,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.739,-3.997,2.258,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.100394,0.00942138,0.490313 kka2_1:8_A229P,kka2_1:8_229,Kka2,kka2_1:8,P00552,0.490313,NO,229,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.739,-3.997,2.258,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.100394,0.00942138,0.490313 kka2_1:8_D82V,kka2_1:8_82,Kka2,kka2_1:8,P00552,0.49039,NO,82,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.946,-3.073,1.127,,0.341,E,b,0.29,0.52,7.463,,63.64,HAH,-1.98,0.100394,0.00637516,0.49039 kka2_1:8_D82V,kka2_1:8_82,Kka2,kka2_1:8,P00552,0.49039,NO,82,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.946,-3.073,1.127,,0.341,E,b,0.29,0.52,7.463,,63.64,HAH,-1.98,0.100394,0.00637516,0.49039 beta-lactamase_M184S,beta-lactamase_184,TEM-1,beta-lactamase,P62593,0.490406,NO,184,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.593,-3.463,1.87,5.39575,,H,A,1.3,-0.87,2.893,,62.94,HHH,-1.41,0.221079,0.00356019,0.490406 beta-lactamase_T187Y,beta-lactamase_187,TEM-1,beta-lactamase,P62593,0.490406,NO,187,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.401,-4.271,2.87,5.11453,0.007,H,A,0.3,-1.19,1.751,,67.48,PPH,-1.69633,0.221079,0.00491782,0.490406 kka2_1:1_Y22L,kka2_1:1_22,Kka2,kka2_1:1,P00552,0.490435,NO,22,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-1.583,-3.408,1.825,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.520039,0.00598977,0.490435 beta-lactamase_2500_A230S,beta-lactamase_2500_230,TEM-1,beta-lactamase_2500,P62593,0.490438,NO,230,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.154,-2.48,1.326,,0.01,E,B,0.46,-1.17,1.171,,50,HHA,-1.079,0.361275,0.00516841,0.490438 beta-lactamase_2500_L28E,beta-lactamase_2500_28,TEM-1,beta-lactamase_2500,P62593,0.490473,NO,28,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.579,-3.677,2.098,,0.277,H,A,0.55,-0.16,2.716,,93.01,PHH,-2.11333,0.361275,0.00359321,0.490473 beta-lactamase_2500_L38N,beta-lactamase_2500_38,TEM-1,beta-lactamase_2500,P62593,0.490473,NO,38,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.343,-4.007,2.664,,0.088,H,A,0.55,0.2,2.71,,64.34,PHO,-1.78033,0.361275,0.00373244,0.490473 kka2_1:2_E96T,kka2_1:2_96,Kka2,kka2_1:2,P00552,0.49049,NO,96,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.573,-2.511,-0.062,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.295029,0.00369441,0.49049 beta-lactamase_2500_M270E,beta-lactamase_2500_270,TEM-1,beta-lactamase_2500,P62593,0.490491,NO,270,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.723,-4.709,2.986,,0.422,H,A,1.59,1.15,2.029,,64.34,PHA,-1.70933,0.361275,0.00767762,0.490491 beta-lactamase_0_D174C,beta-lactamase_0_174,TEM-1,beta-lactamase_0,P62593,0.490519,NO,174,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.738,-5.087,4.349,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.0500837,0.00125633,0.490519 kka2_1:4_N200F,kka2_1:4_200,Kka2,kka2_1:4,P00552,0.4906,NO,200,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-2.446,-4.524,2.078,,0.756,T,L,0.61,-0.08,1.746,,64.39,APO,-2.08,0.168804,0.00838549,0.4906 kka2_1:8_F171S,kka2_1:8_171,Kka2,kka2_1:8,P00552,0.490701,NO,171,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.326,-3.759,2.433,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.100394,0.00821426,0.490701 kka2_1:8_F171S,kka2_1:8_171,Kka2,kka2_1:8,P00552,0.490701,NO,171,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.326,-3.759,2.433,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.100394,0.00821426,0.490701 kka2_1:8_V186M,kka2_1:8_186,Kka2,kka2_1:8,P00552,0.490701,NO,186,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.011,-4.138,3.127,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.100394,0.00409703,0.490701 kka2_1:8_V186M,kka2_1:8_186,Kka2,kka2_1:8,P00552,0.490701,NO,186,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.011,-4.138,3.127,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.100394,0.00409703,0.490701 beta-lactamase_39_A124D,beta-lactamase_39_124,TEM-1,beta-lactamase_39,P62593,0.490716,NO,124,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.181,-3.709,2.528,,,H,A,0.46,-0.9,1.367,,64.34,HHH,-1.152,0.0495842,0.00481399,0.490716 beta-lactamase_2500_L47C,beta-lactamase_2500_47,TEM-1,beta-lactamase_2500,P62593,0.490737,NO,47,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.876,-5.002,3.126,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.361275,0.00439844,0.490737 kka2_1:8_G30Y,kka2_1:8_30,Kka2,kka2_1:8,P00552,0.490842,NO,30,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.596,-4.416,3.82,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.100394,0.00159208,0.490842 kka2_1:8_G30Y,kka2_1:8_30,Kka2,kka2_1:8,P00552,0.490842,NO,30,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.596,-4.416,3.82,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.100394,0.00159208,0.490842 kka2_1:2_K112N,kka2_1:2_112,Kka2,kka2_1:2,P00552,0.491,NO,112,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-2.491,-3.976,1.485,,0.076,H,A,2.34,-1.37,23.433,23.433,56.06,ABH,-2.00133,0.295029,0.00645389,0.491 beta-lactamase_2500_G216C,beta-lactamase_2500_216,TEM-1,beta-lactamase_2500,P62593,0.491036,NO,216,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.477,-5.186,3.709,,0.437,I,A,0.29,-0.58,1.983,,74.48,HOO,-1.68067,0.361275,0.00639568,0.491036 beta-lactamase_2500_S51V,beta-lactamase_2500_51,TEM-1,beta-lactamase_2500,P62593,0.491118,NO,51,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.526,-3.559,2.033,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.361275,0.00504821,0.491118 kka2_1:8_E262Q,kka2_1:8_262,Kka2,kka2_1:8,P00552,0.491165,NO,262,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-0.829,-2.552,1.723,,0.059,G,A,1.52,-0.18,0.837,,42.42,AAH,-0.816,0.100394,0.0191586,0.491165 kka2_1:8_E262Q,kka2_1:8_262,Kka2,kka2_1:8,P00552,0.491165,NO,262,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-0.829,-2.552,1.723,,0.059,G,A,1.52,-0.18,0.837,,42.42,AAH,-0.816,0.100394,0.0191586,0.491165 kka2_1:8_R211D,kka2_1:8_211,Kka2,kka2_1:8,P00552,0.491216,NO,211,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-0.899,-3.783,2.884,,0.12,T,a,0.16,-0.39,0.615,,49.62,OBH,-0.966,0.100394,0.00204888,0.491216 kka2_1:8_R211D,kka2_1:8_211,Kka2,kka2_1:8,P00552,0.491216,NO,211,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-0.899,-3.783,2.884,,0.12,T,a,0.16,-0.39,0.615,,49.62,OBH,-0.966,0.100394,0.00204888,0.491216 kka2_1:4_M120W,kka2_1:4_120,Kka2,kka2_1:4,P00552,0.491234,NO,120,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-3.877,-5.169,1.292,,,H,A,0.55,-0.42,2.259,,92.05,HHB,-2.16733,0.168804,0.00265808,0.491234 beta-lactamase_625_G265I,beta-lactamase_625_265,TEM-1,beta-lactamase_625,P62593,0.491298,NO,265,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.213352,0.00811926,0.491298 kka2_1:2_E169Y,kka2_1:2_169,Kka2,kka2_1:2,P00552,0.491321,NO,169,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.996,-4.385,2.389,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.295029,0.00730086,0.491321 beta-lactamase_2500_F70T,beta-lactamase_2500_70,TEM-1,beta-lactamase_2500,P62593,0.491385,NO,70,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.169,-3.571,2.402,,,H,A,0.58,-1.34,1.918,,63.99,PHB,-0.980667,0.361275,0.00193499,0.491385 beta-lactamase_625_G281N,beta-lactamase_625_281,TEM-1,beta-lactamase_625,P62593,0.491463,NO,281,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.213352,0.0406482,0.491463 kka2_1:8_A34P,kka2_1:8_34,Kka2,kka2_1:8,P00552,0.491475,NO,34,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.928,-3.715,2.787,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.100394,0.00343484,0.491475 kka2_1:8_A34P,kka2_1:8_34,Kka2,kka2_1:8,P00552,0.491475,NO,34,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.928,-3.715,2.787,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.100394,0.00343484,0.491475 kka2_1:1_L212V,kka2_1:1_212,Kka2,kka2_1:1,P00552,0.491492,NO,212,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.904,-2.413,1.509,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.520039,0.0031426,0.491492 kka2_1:2_D190G,kka2_1:2_190,Kka2,kka2_1:2,P00552,0.491684,NO,190,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.708,-3.161,2.453,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.295029,0.00247989,0.491684 kka2_1:1_L243T,kka2_1:1_243,Kka2,kka2_1:1,P00552,0.49173,NO,243,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-2.651,-2.872,0.221,,0.277,H,A,0.55,-0.67,4.334,,92.05,HHH,-2.03767,0.520039,0.00884927,0.49173 beta-lactamase_2500_L136A,beta-lactamase_2500_136,TEM-1,beta-lactamase_2500,P62593,0.491772,NO,136,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.232,-3.144,1.912,,,H,A,0.55,-0.34,1.36,,48.95,HHH,-1.088,0.361275,0.00442304,0.491772 kka2_1:8_R226H,kka2_1:8_226,Kka2,kka2_1:8,P00552,0.491784,NO,226,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.392,-2.664,1.272,,0.222,H,A,0.16,-0.71,3.818,,56.06,PBA,-1.84767,0.100394,0.0108032,0.491784 kka2_1:8_R226H,kka2_1:8_226,Kka2,kka2_1:8,P00552,0.491784,NO,226,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.392,-2.664,1.272,,0.222,H,A,0.16,-0.71,3.818,,56.06,PBA,-1.84767,0.100394,0.0108032,0.491784 kka2_1:4_A222Y,kka2_1:4_222,Kka2,kka2_1:4,P00552,0.49179,NO,222,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.725,-4.191,3.466,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.168804,0.00207657,0.49179 kka2_1:1_D118Q,kka2_1:1_118,Kka2,kka2_1:1,P00552,0.4918,NO,118,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.07,-2.739,0.669,,0.61,H,A,0.75,-0.05,13.434,13.434,64.39,HAH,-1.32367,0.520039,0.0067852,0.4918 beta-lactamase_2500_G265T,beta-lactamase_2500_265,TEM-1,beta-lactamase_2500,P62593,0.491834,NO,265,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.361275,0.00811926,0.491834 beta-lactamase_625_E119Y,beta-lactamase_625_119,TEM-1,beta-lactamase_625,P62593,0.491877,NO,119,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.412,-4.336,2.924,,0.358,H,A,1.04,0.51,1.034,,63.99,BAH,-1.623,0.213352,0.00386966,0.491877 beta-lactamase_2500_A246T,beta-lactamase_2500_246,TEM-1,beta-lactamase_2500,P62593,0.491908,NO,246,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.121,-3.507,1.386,,0.01,E,B,0.46,-1.01,0.753,,73.78,HHH,-1.55633,0.361275,0.00569458,0.491908 kka2_1:1_C192R,kka2_1:1_192,Kka2,kka2_1:1,P00552,0.49193,NO,192,C,R,CR,Special,PositiveCharge,5.07,6.34148,1.27148,180,121,174,53,108.5,173.4,64.9,-1.067,-4.134,3.067,,0.095,.,B,0.46,-0.75,2.749,,50,HOH,-0.960333,0.520039,0.00485428,0.49193 Ubiquitin_I36P,Ubiquitin_36,Uba1,Ubiquitin,P0CG48,0.491935,NO,36,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.477,-4.009,2.532,5.1035,0.203,,B,0.27,-0.22,1.552,,30.8,OHO,-1.30767,0.205827,0.000630555,0.491935 Ubiquitin_L8G,Ubiquitin_8,Uba1,Ubiquitin,P0CG48,0.491935,NO,8,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.723,-3.602,1.879,5.28016,0.664,T,A,0.08,-0.34,0.664,,29.05,PHP,-1.51567,0.205827,0.000726165,0.491935 Ubiquitin_L8R,Ubiquitin_8,Uba1,Ubiquitin,P0CG48,0.491935,NO,8,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.723,-2.97,1.247,5.28016,0.664,T,A,0.08,-0.34,0.664,,29.05,PHP,-1.51567,0.205827,0.000726165,0.491935 Ubiquitin_S65P,Ubiquitin_65,Uba1,Ubiquitin,P0CG48,0.491935,NO,65,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.535,-2.891,1.356,4.99442,0.168,,b,0.25,-0.68,16.756,16.756,33.87,APP,-1.626,0.205827,0.000546776,0.491935 Ubiquitin_T9D,Ubiquitin_9,Uba1,Ubiquitin,P0CG48,0.491935,NO,9,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.409,-3.518,2.109,5.24336,0.777,T,A,2.12,-0.12,2.705,,29.93,HPO,-1.50933,0.205827,0.000630716,0.491935 kka2_1:4_S105H,kka2_1:4_105,Kka2,kka2_1:4,P00552,0.491939,NO,105,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.945,-4.83,2.885,,0.056,S,B,0.77,-1.04,3.442,,65.53,PPB,-2.17033,0.168804,0.00847233,0.491939 kka2_1:4_E182L,kka2_1:4_182,Kka2,kka2_1:4,P00552,0.49196,NO,182,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.516,-3.646,2.13,,0.326,.,B,1.04,0.75,4.755,,65.53,OAA,-1.806,0.168804,0.00641548,0.49196 kka2_1:1_T130I,kka2_1:1_130,Kka2,kka2_1:1,P00552,0.492015,NO,130,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.392,-3.995,1.603,,0.561,G,A,0.22,0.77,0.5,,92.05,HPO,-1.62633,0.520039,0.00804204,0.492015 kka2_1:1_R38H,kka2_1:1_38,Kka2,kka2_1:1,P00552,0.492055,NO,38,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.207,-4.545,3.338,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.520039,0.00372499,0.492055 beta-lactamase_2500_P250Y,beta-lactamase_2500_250,TEM-1,beta-lactamase_2500,P62593,0.492057,NO,250,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.361275,0.00550899,0.492057 kka2_1:1_E199D,kka2_1:1_199,Kka2,kka2_1:1,P00552,0.492068,NO,199,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.234,-2.172,-0.062,,0.508,E,B,1.04,-0.43,3.012,,65.53,HAP,-2.133,0.520039,0.00854122,0.492068 beta-lactamase_2500_N173P,beta-lactamase_2500_173,TEM-1,beta-lactamase_2500,P62593,0.492086,NO,173,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-2.663,-3.891,1.228,,1.044,T,l,0.61,1.25,1.88,,77.62,OPA,-1.46633,0.361275,0.0033769,0.492086 kka2_1:1_V242W,kka2_1:1_242,Kka2,kka2_1:1,P00552,0.492123,NO,242,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-2.687,-5.598,2.911,,0.75,H,A,0.44,-0.37,4.987,,71.59,HHH,-2.16533,0.520039,0.0102575,0.492123 beta-lactamase_2500_G76W,beta-lactamase_2500_76,TEM-1,beta-lactamase_2500,P62593,0.492132,NO,76,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.189,-5.284,4.095,,,H,A,0.29,-0.67,1.012,,67.83,OOH,-1.22267,0.361275,0.00476637,0.492132 beta-lactamase_2500_M184C,beta-lactamase_2500_184,TEM-1,beta-lactamase_2500,P62593,0.492279,NO,184,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.593,-4.787,3.194,,,H,A,0.55,-0.87,2.893,,62.94,HHH,-1.41,0.361275,0.00356019,0.492279 kka2_1:8_L184N,kka2_1:8_184,Kka2,kka2_1:8,P00552,0.492324,NO,184,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.496,-4.154,2.658,,0.489,E,B,0.55,-0.06,4.495,,63.26,AHH,-1.24833,0.100394,0.00518742,0.492324 kka2_1:8_L184N,kka2_1:8_184,Kka2,kka2_1:8,P00552,0.492324,NO,184,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.496,-4.154,2.658,,0.489,E,B,0.55,-0.06,4.495,,63.26,AHH,-1.24833,0.100394,0.00518742,0.492324 beta-lactamase_2500_R92G,beta-lactamase_2500_92,TEM-1,beta-lactamase_2500,P62593,0.492449,NO,92,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.718,-3.552,1.834,,0.479,E,B,1.2,1.36,3.069,,65.38,BBH,-1.50367,0.361275,0.00429626,0.492449 beta-lactamase_2500_G154T,beta-lactamase_2500_154,TEM-1,beta-lactamase_2500,P62593,0.49246,NO,154,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.823,-3.619,2.796,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.361275,0.00180205,0.49246 kka2_1:1_G164S,kka2_1:1_164,Kka2,kka2_1:1,P00552,0.492547,NO,164,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.869,-2.388,1.519,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.520039,0.00442091,0.492547 beta-lactamase_2500_D161C,beta-lactamase_2500_161,TEM-1,beta-lactamase_2500,P62593,0.492632,NO,161,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.891,-5.1,4.209,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.361275,0.000897697,0.492632 kka2_1:1_S251E,kka2_1:1_251,Kka2,kka2_1:1,P00552,0.492652,NO,251,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.636,-2.355,-0.281,,0.712,H,A,0.27,-0.25,1.356,,71.59,APP,-2.09367,0.520039,0.0138916,0.492652 kka2_1:1_F263L,kka2_1:1_263,Kka2,kka2_1:1,P00552,0.492749,NO,263,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-0.911,-2.161,1.25,,0.006,G,A,0.58,-0.12,2.284,,45.83,AHH,-0.92,0.520039,0.0172454,0.492749 beta-lactamase_0_L89E,beta-lactamase_0_89,TEM-1,beta-lactamase_0,P62593,0.492751,NO,89,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.096,-3.801,2.705,,0.168,T,A,0.55,0.63,2.373,,64.34,PHO,-1.75767,0.0500837,0.00207068,0.492751 beta-lactamase_625_T27R,beta-lactamase_625_27,TEM-1,beta-lactamase_625,P62593,0.492783,NO,27,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.905,-3.861,1.956,,0.007,H,A,0.22,-0.37,3.72,,93.01,APH,-1.97933,0.213352,0.00306559,0.492783 kka2_1:8_L174G,kka2_1:8_174,Kka2,kka2_1:8,P00552,0.492867,NO,174,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.952,-3.755,2.803,,,H,A,1.59,-0.31,1.204,,51.89,BHB,-2.08533,0.100394,0.00438501,0.492867 kka2_1:8_L174G,kka2_1:8_174,Kka2,kka2_1:8,P00552,0.492867,NO,174,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.952,-3.755,2.803,,,H,A,1.59,-0.31,1.204,,51.89,BHB,-2.08533,0.100394,0.00438501,0.492867 beta-lactamase_625_L79A,beta-lactamase_625_79,TEM-1,beta-lactamase_625,P62593,0.4929,NO,79,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.842,-3.103,2.261,,0.007,H,A,0.55,-0.16,0.935,,50.35,HHP,-1.44333,0.213352,0.000947397,0.4929 kka2_1:8_L170E,kka2_1:8_170,Kka2,kka2_1:8,P00552,0.492925,NO,170,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.28,-3.891,2.611,,0.029,H,A,1.59,0.11,1.453,,62.5,AHH,-1.534,0.100394,0.00730791,0.492925 kka2_1:8_L170E,kka2_1:8_170,Kka2,kka2_1:8,P00552,0.492925,NO,170,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.28,-3.891,2.611,,0.029,H,A,1.59,0.11,1.453,,62.5,AHH,-1.534,0.100394,0.00730791,0.492925 beta-lactamase_2500_G281M,beta-lactamase_2500_281,TEM-1,beta-lactamase_2500,P62593,0.492962,NO,281,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.361275,0.0406482,0.492962 kka2_1:1_D261Q,kka2_1:1_261,Kka2,kka2_1:1,P00552,0.492971,NO,261,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.708,-3.703,2.995,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.520039,0.0224846,0.492971 beta-lactamase_2500_I285W,beta-lactamase_2500_285,TEM-1,beta-lactamase_2500,P62593,0.492986,NO,285,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.361275,0.101555,0.492986 beta-lactamase_L223Y,beta-lactamase_223,TEM-1,beta-lactamase,P62593,0.492993,NO,223,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.055,-3.889,2.834,5.42318,0.27,,B,1.3,0.09,1.511,,74.48,HHO,-1.35033,0.221079,0.00372793,0.492993 kka2_1:2_C131Y,kka2_1:2_131,Kka2,kka2_1:2,P00552,0.493021,NO,131,C,Y,CY,Special,Hydrophobic,5.07,5.66,0.59,194,121,181,60,108.5,193.6,85.1,-0.831,-4.191,3.36,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.295029,0.00170814,0.493021 beta-lactamase_L218S,beta-lactamase_218,TEM-1,beta-lactamase,P62593,0.493058,NO,218,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.391,-2.79,1.399,4.88972,,I,b,2.89,-0.53,12.788,12.788,74.48,OHH,-1.58867,0.221079,0.00618274,0.493058 kka2_1:4_D190E,kka2_1:4_190,Kka2,kka2_1:4,P00552,0.493126,NO,190,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.708,-2.793,2.085,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.168804,0.00247989,0.493126 beta-lactamase_625_L49R,beta-lactamase_625_49,TEM-1,beta-lactamase_625,P62593,0.493134,NO,49,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.897,-3.032,1.135,,0.131,T,A,0.55,0.04,3.112,,64.69,AHP,-1.99233,0.213352,0.00401477,0.493134 kka2_1:8_I207H,kka2_1:8_207,Kka2,kka2_1:8,P00552,0.493171,NO,207,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.175,-5.02,3.845,,0.293,,B,1.52,-1.12,1.306,,56.06,HHA,-1.07733,0.100394,0.00611824,0.493171 kka2_1:8_I207H,kka2_1:8_207,Kka2,kka2_1:8,P00552,0.493171,NO,207,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.175,-5.02,3.845,,0.293,,B,1.52,-1.12,1.306,,56.06,HHA,-1.07733,0.100394,0.00611824,0.493171 beta-lactamase_Y95G,beta-lactamase_95,TEM-1,beta-lactamase,P62593,0.493269,NO,95,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-1.715,-3.781,2.066,5.67068,0.122,,b,0.96,-0.37,2.341,,77.62,BHP,-2.16167,0.221079,0.00479449,0.493269 kka2_1:1_G151D,kka2_1:1_151,Kka2,kka2_1:1,P00552,0.493296,NO,151,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.873,-2.683,1.81,,0.678,T,l,0.29,1.36,0.226,,49.62,HOH,-1.11433,0.520039,0.00339918,0.493296 beta-lactamase_2500_L89T,beta-lactamase_2500_89,TEM-1,beta-lactamase_2500,P62593,0.493298,NO,89,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.096,-3.474,2.378,,0.168,T,A,0.55,0.63,2.066,,64.34,PHO,-1.75767,0.361275,0.00207068,0.493298 kka2_1:1_P249S,kka2_1:1_249,Kka2,kka2_1:1,P00552,0.493335,NO,249,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.867,-3.595,1.728,,0.406,.,B,0.52,-0.01,8.037,8.037,92.05,HOA,-1.66867,0.520039,0.011045,0.493335 beta-lactamase_625_T126Y,beta-lactamase_625_126,TEM-1,beta-lactamase_625,P62593,0.493457,NO,126,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.122,-4.294,3.172,,0.05,H,A,0.22,-0.05,0.817,,44.41,HPH,-1.60467,0.213352,0.00244552,0.493457 kka2_1:1_Q252C,kka2_1:1_252,Kka2,kka2_1:1,P00552,0.493521,NO,252,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.63,-5.184,2.554,,0.906,H,A,0.64,0.35,1.369,,92.05,PPB,-2.20733,0.520039,0.0121001,0.493521 kka2_1:4_C209D,kka2_1:4_209,Kka2,kka2_1:4,P00552,0.493537,NO,209,C,D,CD,Special,negativeCharge,5.07,5.0516,-0.0184,154,121,133,12,108.5,111.1,2.6,-0.906,-3.991,3.085,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.168804,0.00260862,0.493537 beta-lactamase_156_S68I,beta-lactamase_156_68,TEM-1,beta-lactamase_156,P62593,0.493581,NO,68,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-0.913,-3.834,2.921,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.111618,0.000800065,0.493581 kka2_1:4_A119R,kka2_1:4_119,Kka2,kka2_1:4,P00552,0.493613,NO,119,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.073,-3.886,2.813,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.168804,0.00441074,0.493613 gb1_K254N,gb1_254,gb1,gb1,P06654,0.493684,NO,254,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.748,-3.313,1.565,,,,,,,1.793,,37.28,ABH,-2.195,0.177985,0.00622711,0.493684 beta-lactamase_2500_T147L,beta-lactamase_2500_147,TEM-1,beta-lactamase_2500,P62593,0.493715,NO,147,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.149,-3.242,2.093,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.361275,0.00226017,0.493715 kka2_1:1_F203S,kka2_1:1_203,Kka2,kka2_1:1,P00552,0.493723,NO,203,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-0.911,-3.673,2.762,,0.26,E,B,0.58,-0.92,7.323,,63.64,BHP,-1.34167,0.520039,0.00318738,0.493723 kka2_1:1_W91S,kka2_1:1_91,Kka2,kka2_1:1,P00552,0.493823,NO,91,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-1.178,-3.808,2.63,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.520039,0.00358653,0.493823 beta-lactamase_156_C75N,beta-lactamase_156_75,TEM-1,beta-lactamase_156,P62593,0.493835,NO,75,C,N,CN,Special,Polar,5.07,5.47157,0.401575,139,121,132,11,108.5,114.1,5.6,-1.245,-3.973,2.728,,,H,A,0.46,-0.87,0.876,,50,HOO,-1.24333,0.111618,0.0034616,0.493835 kka2_1:1_A35W,kka2_1:1_35,Kka2,kka2_1:1,P00552,0.49388,NO,35,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.127,-5.562,3.435,,0.107,E,B,0.46,1.05,8.405,8.405,71.59,HHH,-1.31767,0.520039,0.00630016,0.49388 beta-lactamase_2500_L197K,beta-lactamase_2500_197,TEM-1,beta-lactamase_2500,P62593,0.493904,NO,197,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.853,-3.679,2.826,,0.007,S,B,0.55,0.33,2.421,,60.14,HHP,-1.833,0.361275,0.00144602,0.493904 kka2_1:8_R140P,kka2_1:8_140,Kka2,kka2_1:8,P00552,0.49394,NO,140,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.351,-3.937,2.586,,0.12,H,A,0.16,0.2,2.874,,53.03,BBH,-1.885,0.100394,0.00430167,0.49394 kka2_1:8_R140P,kka2_1:8_140,Kka2,kka2_1:8,P00552,0.49394,NO,140,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.351,-3.937,2.586,,0.12,H,A,0.16,0.2,2.874,,53.03,BBH,-1.885,0.100394,0.00430167,0.49394 beta-lactamase_625_R59G,beta-lactamase_625_59,TEM-1,beta-lactamase_625,P62593,0.494043,NO,59,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.345,-3.412,2.067,,0.329,S,L,1.2,-0.09,2.995,,73.08,HBO,-2.24267,0.213352,0.00318082,0.494043 kka2_1:1_S114Q,kka2_1:1_114,Kka2,kka2_1:1,P00552,0.494089,NO,114,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.527,-3.268,0.741,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.520039,0.00705262,0.494089 kka2_1:1_A229R,kka2_1:1_229,Kka2,kka2_1:1,P00552,0.494214,NO,229,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.739,-2.242,0.503,,0.32,H,A,0.46,-0.7,6.549,,63.64,HHA,-1.851,0.520039,0.00942138,0.494214 WW_domain_N191K,WW_domain_191,Yap65,WW_domain,P46937,0.494241,NO,191,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-1.519,-2.172,0.653,5.96016,,,,,,5.117,,66.07,HPB,-1.554,0.153962,0.00270999,0.494241 beta-lactamase_D174F,beta-lactamase_174,TEM-1,beta-lactamase,P62593,0.494398,NO,174,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.738,-4.292,3.554,5.44133,0.238,,B,1.22,-0.1,,,,PAA,-1.91233,0.221079,0.00125633,0.494398 kka2_1:8_V49S,kka2_1:8_49,Kka2,kka2_1:8,P00552,0.494476,NO,49,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.614,-2.896,1.282,,,E,B,1.48,-0.77,1.31,,64.39,HHB,-1.3,0.100394,0.00615685,0.494476 kka2_1:8_V49S,kka2_1:8_49,Kka2,kka2_1:8,P00552,0.494476,NO,49,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.614,-2.896,1.282,,,E,B,1.48,-0.77,1.31,,64.39,HHB,-1.3,0.100394,0.00615685,0.494476 beta-lactamase_0_F70N,beta-lactamase_0_70,TEM-1,beta-lactamase_0,P62593,0.494516,NO,70,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.169,-4.034,2.865,,,H,A,0.58,-1.34,2.153,,63.99,PHB,-0.980667,0.0500837,0.00193499,0.494516 beta-lactamase_S104Y,beta-lactamase_104,TEM-1,beta-lactamase,P62593,0.494595,NO,104,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.015,-4.223,3.208,4.92365,0.04,,b,0.82,0.57,4.02,,63.29,HPO,-1.05267,0.221079,0.00218083,0.494595 kka2_1:2_E142F,kka2_1:2_142,Kka2,kka2_1:2,P00552,0.494608,NO,142,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.221,-4.452,2.231,,0.471,H,A,1.52,0.85,3.693,,65.53,HAB,-2.08033,0.295029,0.00748883,0.494608 kka2_1:2_D159G,kka2_1:2_159,Kka2,kka2_1:2,P00552,0.494624,NO,159,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.82,-2.148,1.328,,0.28,.,B,0.75,1.25,0.899,,48.11,HAA,-1.48333,0.295029,0.0030485,0.494624 beta-lactamase_625_V78H,beta-lactamase_625_78,TEM-1,beta-lactamase_625,P62593,0.494786,NO,78,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.459,-5.015,3.556,,,H,A,0.44,-0.47,2.045,,63.64,HHH,-1.17833,0.213352,0.00492501,0.494786 kka2_1:2_L174F,kka2_1:2_174,Kka2,kka2_1:2,P00552,0.494839,NO,174,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.952,-3.775,2.823,,,H,A,1.59,-0.31,8.521,,51.89,BHB,-2.08533,0.295029,0.00438501,0.494839 beta-lactamase_G114R,beta-lactamase_114,TEM-1,beta-lactamase,P62593,0.494935,NO,114,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.094,-2.891,1.797,4.92659,0.011,,p,0.77,0.35,2.148,,41.61,AOH,-1.43733,0.221079,0.00224919,0.494935 beta-lactamase_625_V117Y,beta-lactamase_625_117,TEM-1,beta-lactamase_625,P62593,0.495054,NO,117,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.53,-2.958,1.428,,,H,A,0.44,-0.34,1.23,,65.03,PHB,-1.741,0.213352,0.00467906,0.495054 beta-lactamase_2500_T198I,beta-lactamase_2500_198,TEM-1,beta-lactamase_2500,P62593,0.495109,NO,198,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.168,-3.831,1.663,,0.489,,B,0.22,-0.13,0.37,,73.78,HPH,-1.98767,0.361275,0.004311,0.495109 beta-lactamase_2500_F149N,beta-lactamase_2500_149,TEM-1,beta-lactamase_2500,P62593,0.495128,NO,149,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.299,-4.055,2.756,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.361275,0.00418462,0.495128 beta-lactamase_0_D83A,beta-lactamase_0_83,TEM-1,beta-lactamase_0,P62593,0.495138,NO,83,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.066,-3.208,2.142,,0.354,H,A,0.75,0.22,0.617,,48.95,HAH,-1.34733,0.0500837,0.00205968,0.495138 beta-lactamase_625_A123F,beta-lactamase_625_123,TEM-1,beta-lactamase_625,P62593,0.495155,NO,123,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.834,-4.065,3.231,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.213352,0.0010157,0.495155 beta-lactamase_2500_L111D,beta-lactamase_2500_111,TEM-1,beta-lactamase_2500,P62593,0.495259,NO,111,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.76,-3.995,2.235,,0.328,T,A,0.55,0.93,1.966,,64.34,BHP,-1.884,0.361275,0.00480671,0.495259 kka2_1:2_L165D,kka2_1:2_165,Kka2,kka2_1:2,P00552,0.495337,NO,165,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-2.453,-3.848,1.395,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.295029,0.00801161,0.495337 beta-lactamase_2500_Y95M,beta-lactamase_2500_95,TEM-1,beta-lactamase_2500,P62593,0.495379,NO,95,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-1.715,-4.404,2.689,,0.122,,b,0.21,-0.37,2.914,,77.62,BHP,-2.16167,0.361275,0.00479449,0.495379 kka2_1:4_L92T,kka2_1:4_92,Kka2,kka2_1:4,P00552,0.495517,NO,92,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.893,-3.472,2.579,,0.007,E,B,0.55,-0.19,1.447,,63.26,HHH,-0.962,0.168804,0.00307177,0.495517 beta-lactamase_R241E,beta-lactamase_241,TEM-1,beta-lactamase,P62593,0.495558,NO,241,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.433,-3.387,1.954,5.02621,0.094,E,B,0.68,-0.16,1.327,,50,PBO,-1.42967,0.221079,0.00452736,0.495558 beta-lactamase_625_G281Y,beta-lactamase_625_281,TEM-1,beta-lactamase_625,P62593,0.495579,NO,281,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.213352,0.0406482,0.495579 beta-lactamase_39_K232T,beta-lactamase_39_232,TEM-1,beta-lactamase_39,P62593,0.495597,NO,232,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.012,-3.464,2.452,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.0495842,0.00313441,0.495597 kka2_1:8_I115F,kka2_1:8_115,Kka2,kka2_1:8,P00552,0.495624,NO,115,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.606,-3.062,1.456,,0.105,H,A,1.52,-1.18,4.064,,65.53,PHH,-2.205,0.100394,0.00836567,0.495624 kka2_1:8_I115F,kka2_1:8_115,Kka2,kka2_1:8,P00552,0.495624,NO,115,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.606,-3.062,1.456,,0.105,H,A,1.52,-1.18,4.064,,65.53,PHH,-2.205,0.100394,0.00836567,0.495624 beta-lactamase_2500_V259M,beta-lactamase_2500_259,TEM-1,beta-lactamase_2500,P62593,0.495658,NO,259,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.361275,0.0070773,0.495658 beta-lactamase_L120H,beta-lactamase_120,TEM-1,beta-lactamase,P62593,0.495669,NO,120,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.044,-3.066,2.022,5.11974,,H,A,1.3,-1.13,1.988,,64.69,AHO,-1.13633,0.221079,0.00143563,0.495669 kka2_1:1_E63V,kka2_1:1_63,Kka2,kka2_1:1,P00552,0.495677,NO,63,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-0.762,-3.557,2.795,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.520039,0.00118399,0.495677 beta-lactamase_2500_S266D,beta-lactamase_2500_266,TEM-1,beta-lactamase_2500,P62593,0.495785,NO,266,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.361275,0.0140785,0.495785 beta-lactamase_625_G114P,beta-lactamase_625_114,TEM-1,beta-lactamase_625,P62593,0.495791,NO,114,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.094,-3.918,2.824,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.213352,0.00224919,0.495791 kka2_1:2_D127R,kka2_1:2_127,Kka2,kka2_1:2,P00552,0.495834,NO,127,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.364,-3.039,1.675,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.295029,0.00660501,0.495834 kka2_1:1_G95L,kka2_1:1_95,Kka2,kka2_1:1,P00552,0.495973,NO,95,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-2.403,-3.574,1.171,,0.126,E,B,0.29,-0.74,7.822,,71.59,HOA,-2.198,0.520039,0.00743616,0.495973 kka2_1:8_D190C,kka2_1:8_190,Kka2,kka2_1:8,P00552,0.496005,NO,190,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.708,-5.115,4.407,,0.213,S,b,0.29,-0.82,,,,OAH,-0.711667,0.100394,0.00247989,0.496005 kka2_1:8_D190C,kka2_1:8_190,Kka2,kka2_1:8,P00552,0.496005,NO,190,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.708,-5.115,4.407,,0.213,S,b,0.29,-0.82,,,,OAH,-0.711667,0.100394,0.00247989,0.496005 kka2_1:1_D82H,kka2_1:1_82,Kka2,kka2_1:1,P00552,0.496016,NO,82,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.946,-4.75,2.804,,0.341,E,b,0.75,0.52,11.345,11.345,63.64,HAH,-1.98,0.520039,0.00637516,0.496016 beta-lactamase_2500_G114F,beta-lactamase_2500_114,TEM-1,beta-lactamase_2500,P62593,0.49611,NO,114,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.094,-4.331,3.237,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.361275,0.00224919,0.49611 kka2_1:4_G99N,kka2_1:4_99,Kka2,kka2_1:4,P00552,0.496125,NO,99,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.596,-3.476,2.88,,0.368,S,g,0.29,-0.87,,,,OOP,-1.63067,0.168804,0.00186055,0.496125 kka2_1:1_T28D,kka2_1:1_28,Kka2,kka2_1:1,P00552,0.496137,NO,28,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.883,-2.685,0.802,,0.353,S,B,0.22,2.02,1.12,,63.64,PPH,-1.74467,0.520039,0.00743084,0.496137 kka2_1:8_V36P,kka2_1:8_36,Kka2,kka2_1:8,P00552,0.496158,NO,36,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-0.898,-3.99,3.092,,0.292,E,B,1.48,0.21,0.938,,52.27,HHH,-1.484,0.100394,0.00245633,0.496158 kka2_1:8_V36P,kka2_1:8_36,Kka2,kka2_1:8,P00552,0.496158,NO,36,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-0.898,-3.99,3.092,,0.292,E,B,1.48,0.21,0.938,,52.27,HHH,-1.484,0.100394,0.00245633,0.496158 beta-lactamase_R202F,beta-lactamase_202,TEM-1,beta-lactamase,P62593,0.496181,NO,202,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.292,-4.334,3.042,5.16273,0.188,H,A,0.68,0.62,1.918,,77.62,PBP,-1.54767,0.221079,0.00321899,0.496181 kka2_1:1_H135P,kka2_1:1_135,Kka2,kka2_1:1,P00552,0.496246,NO,135,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-1.331,-3.963,2.632,,0.071,.,a,0.17,0.65,3.574,,53.03,ABP,-1.77367,0.520039,0.00532566,0.496246 beta-lactamase_625_G52C,beta-lactamase_625_52,TEM-1,beta-lactamase_625,P62593,0.496419,NO,52,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.149,-5.084,3.935,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.213352,0.00340138,0.496419 beta-lactamase_G242N,beta-lactamase_242,TEM-1,beta-lactamase,P62593,0.496434,NO,242,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.319,-1.654,0.335,4.68003,,E,B,0.87,-1.05,1.079,,50,BOH,-1.428,0.221079,0.00452879,0.496434 kka2_1:8_A119Q,kka2_1:8_119,Kka2,kka2_1:8,P00552,0.496462,NO,119,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.073,-4.017,2.944,,0.019,H,A,0.46,-0.57,1.511,,71.59,AHH,-2.34,0.100394,0.00441074,0.496462 kka2_1:8_A119Q,kka2_1:8_119,Kka2,kka2_1:8,P00552,0.496462,NO,119,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.073,-4.017,2.944,,0.019,H,A,0.46,-0.57,1.511,,71.59,AHH,-2.34,0.100394,0.00441074,0.496462 beta-lactamase_L167D,beta-lactamase_167,TEM-1,beta-lactamase,P62593,0.496481,NO,167,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.138,-4.03,2.892,5.13111,0.015,G,A,0.08,-0.63,0.4,,64.69,AHP,-1.30767,0.221079,0.00303566,0.496481 beta-lactamase_39_R257D,beta-lactamase_39_257,TEM-1,beta-lactamase_39,P62593,0.496503,NO,257,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.0495842,0.00756629,0.496503 beta-lactamase_0_S256H,beta-lactamase_0_256,TEM-1,beta-lactamase_0,P62593,0.496529,NO,256,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.0500837,0.00710634,0.496529 beta-lactamase_2500_R91L,beta-lactamase_2500_91,TEM-1,beta-lactamase_2500,P62593,0.496541,NO,91,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.392,-3.471,2.079,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.361275,0.00380226,0.496541 beta-lactamase_2500_L223R,beta-lactamase_2500_223,TEM-1,beta-lactamase_2500,P62593,0.496615,NO,223,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.055,-4.022,2.967,,0.27,,B,0.55,0.09,1.334,,74.48,HHO,-1.35033,0.361275,0.00372793,0.496615 kka2_1:2_E86R,kka2_1:2_86,Kka2,kka2_1:2,P00552,0.49662,NO,86,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.86,-3.888,2.028,,0.369,.,B,1.04,1.92,3.573,,63.26,PAH,-1.98067,0.295029,0.00642858,0.49662 kka2_1:1_D82A,kka2_1:1_82,Kka2,kka2_1:1,P00552,0.496679,NO,82,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.946,-1.898,-0.048,,0.341,E,b,0.75,0.52,11.345,11.345,63.64,HAH,-1.98,0.520039,0.00637516,0.496679 beta-lactamase_0_L120F,beta-lactamase_0_120,TEM-1,beta-lactamase_0,P62593,0.496818,NO,120,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.044,-2.785,1.741,,,H,A,0.55,-1.13,1.2,,64.69,AHO,-1.13633,0.0500837,0.00143563,0.496818 kka2_1:8_G189Y,kka2_1:8_189,Kka2,kka2_1:8,P00552,0.496842,NO,189,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.596,-4.416,3.82,,0.034,S,l,0.75,-0.99,,,,BOA,-0.739,0.100394,0.00253688,0.496842 kka2_1:8_G189Y,kka2_1:8_189,Kka2,kka2_1:8,P00552,0.496842,NO,189,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.596,-4.416,3.82,,0.034,S,l,0.75,-0.99,,,,BOA,-0.739,0.100394,0.00253688,0.496842 beta-lactamase_P65L,beta-lactamase_65,TEM-1,beta-lactamase,P62593,0.496884,NO,65,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.894,-2.247,1.353,5.59094,0.098,E,B,0.23,-0.62,0.623,,40.56,HOH,-1.03233,0.221079,0.00152776,0.496884 beta-lactamase_2500_W288M,beta-lactamase_2500_288,TEM-1,beta-lactamase_2500,P62593,0.496942,NO,288,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,,,,,,,,,,,,,BHO,,0.361275,,0.496942 beta-lactamase_2500_T179A,beta-lactamase_2500_179,TEM-1,beta-lactamase_2500,P62593,0.497026,NO,179,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.085,-2.334,1.249,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.361275,0.00226045,0.497026 Pab1_G163P,Pab1_163,Pab1,Pab1,P04147,0.497125,NO,163,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.809,-3.697,2.888,,0.356,B,g,,0.55,,,,POB,-1.80667,0.175299,0.00030953,0.497125 beta-lactamase_156_T179M,beta-lactamase_156_179,TEM-1,beta-lactamase_156,P62593,0.497229,NO,179,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.085,-4.564,3.479,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.111618,0.00226045,0.497229 kka2_1:1_S251D,kka2_1:1_251,Kka2,kka2_1:1,P00552,0.497302,NO,251,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.636,-2.837,0.201,,0.712,H,A,0.27,-0.25,1.356,,71.59,APP,-2.09367,0.520039,0.0138916,0.497302 beta-lactamase_2500_G114S,beta-lactamase_2500_114,TEM-1,beta-lactamase_2500,P62593,0.497376,NO,114,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.094,-2.588,1.494,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.361275,0.00224919,0.497376 gb1_K254Y,gb1_254,gb1,gb1,P06654,0.497383,NO,254,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.748,-3.967,2.219,,,,,,,1.793,,37.28,ABH,-2.195,0.177985,0.00622711,0.497383 beta-lactamase_39_D155Y,beta-lactamase_39_155,TEM-1,beta-lactamase_39,P62593,0.497414,NO,155,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.889,-4.387,3.498,,0.049,,B,0.75,-0.9,3.208,,64.69,OAB,-1.62267,0.0495842,0.00135315,0.497414 beta-lactamase_2500_L197A,beta-lactamase_2500_197,TEM-1,beta-lactamase_2500,P62593,0.497522,NO,197,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.853,-2.357,1.504,,0.007,S,B,0.55,0.33,2.421,,60.14,HHP,-1.833,0.361275,0.00144602,0.497522 kka2_1:8_V185F,kka2_1:8_185,Kka2,kka2_1:8,P00552,0.497527,NO,185,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.045,-3.962,2.917,,0.058,E,B,1.48,-0.49,1.234,,46.97,HHH,-1.184,0.100394,0.00367031,0.497527 kka2_1:8_V185F,kka2_1:8_185,Kka2,kka2_1:8,P00552,0.497527,NO,185,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.045,-3.962,2.917,,0.058,E,B,1.48,-0.49,1.234,,46.97,HHH,-1.184,0.100394,0.00367031,0.497527 kka2_1:1_A108H,kka2_1:1_108,Kka2,kka2_1:1,P00552,0.497537,NO,108,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.061,-3.555,1.494,,0.243,.,B,0.46,-1.34,3.156,,71.59,HHO,-1.57033,0.520039,0.00751209,0.497537 kka2_1:2_L57N,kka2_1:2_57,Kka2,kka2_1:2,P00552,0.497554,NO,57,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.898,-4.124,2.226,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.295029,0.00723769,0.497554 kka2_1:2_A215R,kka2_1:2_215,Kka2,kka2_1:2,P00552,0.497604,NO,215,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.968,-3.821,2.853,,0.039,E,B,0.46,-0.59,2.137,,50.38,HHA,-1.00467,0.295029,0.00529129,0.497604 beta-lactamase_F17D,beta-lactamase_17,TEM-1,beta-lactamase,P62593,0.49763,NO,17,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-2.337,-3.869,1.532,,,,,,,2.192,,67.83,HHO,-2.17733,0.221079,0.00216499,0.49763 beta-lactamase_2500_L38E,beta-lactamase_2500_38,TEM-1,beta-lactamase_2500,P62593,0.497785,NO,38,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.343,-3.797,2.454,,0.088,H,A,0.55,0.2,2.71,,64.34,PHO,-1.78033,0.361275,0.00373244,0.497785 beta-lactamase_W208T,beta-lactamase_208,TEM-1,beta-lactamase,P62593,0.497802,NO,208,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-0.818,-3.646,2.828,5.26277,0.067,H,A,0.99,-0.65,,,,AHH,-1.44133,0.221079,0.00126609,0.497802 beta-lactamase_2500_P143S,beta-lactamase_2500_143,TEM-1,beta-lactamase_2500,P62593,0.49787,NO,143,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.967,-3.441,2.474,,0.075,H,A,0.52,-0.37,0.479,,66.78,OOB,-1.354,0.361275,0.00114551,0.49787 WW_domain_G185W,WW_domain_185,Yap65,WW_domain,P46937,0.497898,NO,185,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.861,-4.874,4.013,6.22337,,,,,,,,,POP,-1.194,0.153962,0.00199178,0.497898 kka2_1:2_F37V,kka2_1:2_37,Kka2,kka2_1:2,P00552,0.497985,NO,37,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.427,-2.858,1.431,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.295029,0.00586193,0.497985 beta-lactamase_39_A246Q,beta-lactamase_39_246,TEM-1,beta-lactamase_39,P62593,0.498035,NO,246,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.121,-4.263,2.142,,0.01,E,B,0.46,-1.01,1.331,,73.78,HHH,-1.55633,0.0495842,0.00569458,0.498035 kka2_1:2_G205V,kka2_1:2_205,Kka2,kka2_1:2,P00552,0.498109,NO,205,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.596,-3.782,3.186,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.295029,0.00221855,0.498109 kka2_1:1_Q26P,kka2_1:1_26,Kka2,kka2_1:1,P00552,0.498145,NO,26,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.18,-2.701,0.521,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.520039,0.00708962,0.498145 beta-lactamase_I45N,beta-lactamase_45,TEM-1,beta-lactamase,P62593,0.498175,NO,45,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-2.421,-3.135,0.714,5.31505,,E,B,1,-0.3,2.256,,77.62,HHA,-2.30267,0.221079,0.00452842,0.498175 kka2_1:8_R211M,kka2_1:8_211,Kka2,kka2_1:8,P00552,0.498207,NO,211,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-0.899,-4.531,3.632,,0.12,T,a,0.16,-0.39,0.615,,49.62,OBH,-0.966,0.100394,0.00204888,0.498207 kka2_1:8_R211M,kka2_1:8_211,Kka2,kka2_1:8,P00552,0.498207,NO,211,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-0.899,-4.531,3.632,,0.12,T,a,0.16,-0.39,0.615,,49.62,OBH,-0.966,0.100394,0.00204888,0.498207 beta-lactamase_2500_P165E,beta-lactamase_2500_165,TEM-1,beta-lactamase_2500,P62593,0.498214,NO,165,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.373,-3.511,2.138,,0.203,T,A,0.52,-0.31,0.414,,73.78,AOA,-1.359,0.361275,0.00549538,0.498214 kka2_1:1_D101N,kka2_1:1_101,Kka2,kka2_1:1,P00552,0.498256,NO,101,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.028,-2.135,1.107,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.520039,0.00423361,0.498256 beta-lactamase_0_V101H,beta-lactamase_0_101,TEM-1,beta-lactamase_0,P62593,0.498329,NO,101,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.295,-4.92,3.625,,0.342,,B,0.44,0,1.61,,73.08,HHA,-1.54367,0.0500837,0.00374492,0.498329 kka2_1:4_F264M,kka2_1:4_264,Kka2,kka2_1:4,P00552,0.498342,NO,264,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.02,-4.352,3.332,,0.296,,?,1.62,0.02,1.93,,71.59,HHO,-0.9655,0.168804,,0.498342 kka2_1:4_D190Y,kka2_1:4_190,Kka2,kka2_1:4,P00552,0.498358,NO,190,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.708,-4.416,3.708,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.168804,0.00247989,0.498358 kka2_1:4_Y22S,kka2_1:4_22,Kka2,kka2_1:4,P00552,0.498358,NO,22,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-1.583,-2.891,1.308,,0.122,.,B,0.21,-0.8,1.838,,65.53,OHA,-1.80333,0.168804,0.00598977,0.498358 kka2_1:1_V36R,kka2_1:1_36,Kka2,kka2_1:1,P00552,0.498386,NO,36,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-0.898,-4.231,3.333,,0.292,E,B,0.44,0.21,0.278,,52.27,HHH,-1.484,0.520039,0.00245633,0.498386 beta-lactamase_2500_D231T,beta-lactamase_2500_231,TEM-1,beta-lactamase_2500,P62593,0.498394,NO,231,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.816,-3.447,2.631,,,E,B,0.75,-1.06,0.319,,65.38,HAB,-0.994,0.361275,0.00107395,0.498394 beta-lactamase_2500_P105S,beta-lactamase_2500_105,TEM-1,beta-lactamase_2500,P62593,0.498508,NO,105,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.813,-2.526,1.713,,0.226,T,A,0.52,0.8,3.1,,63.29,POH,-1.01533,0.361275,0.0011981,0.498508 kka2_1:4_C77R,kka2_1:4_77,Kka2,kka2_1:4,P00552,0.498539,NO,77,C,R,CR,Special,PositiveCharge,5.07,6.34148,1.27148,180,121,174,53,108.5,173.4,64.9,-1.477,-4.125,2.648,,0.229,B,b,0.46,-0.57,2.499,,63.26,OOH,-1.55667,0.168804,0.00441216,0.498539 beta-lactamase_625_D83C,beta-lactamase_625_83,TEM-1,beta-lactamase_625,P62593,0.498623,NO,83,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.066,-5.147,4.081,,0.354,H,A,0.75,0.22,0.239,,48.95,HAH,-1.34733,0.213352,0.00205968,0.498623 kka2_1:1_E230T,kka2_1:1_230,Kka2,kka2_1:1,P00552,0.498716,NO,230,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.672,-3.072,0.4,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.520039,0.00920051,0.498716 kka2_1:2_N200T,kka2_1:2_200,Kka2,kka2_1:2,P00552,0.498729,NO,200,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-2.446,-3.096,0.65,,0.756,T,L,0.61,-0.08,2.836,,64.39,APO,-2.08,0.295029,0.00838549,0.498729 beta-lactamase_156_G243M,beta-lactamase_156_243,TEM-1,beta-lactamase_156,P62593,0.49877,NO,243,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.532,,,,,E,B,0.77,-1.24,2.866,,50,BOH,-1.46867,0.111618,0.00464034,0.49877 beta-lactamase_2500_R41C,beta-lactamase_2500_41,TEM-1,beta-lactamase_2500,P62593,0.498798,NO,41,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-0.942,-5.05,4.108,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.361275,0.00123327,0.498798 beta-lactamase_A34E,beta-lactamase_34,TEM-1,beta-lactamase,P62593,0.498854,NO,34,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.059,-3.743,1.684,4.9129,,H,A,0.75,-0.54,3.614,,73.78,AHA,-1.74967,0.221079,0.00407913,0.498854 beta-lactamase_2500_G114C,beta-lactamase_2500_114,TEM-1,beta-lactamase_2500,P62593,0.498876,NO,114,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.094,-5.014,3.92,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.361275,0.00224919,0.498876 kka2_1:4_L223K,kka2_1:4_223,Kka2,kka2_1:4,P00552,0.498933,NO,223,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.861,-3.793,2.932,,,H,A,1.59,-1.24,1.268,,50,HHH,-0.854333,0.168804,0.00253574,0.498933 beta-lactamase_A230Y,beta-lactamase_230,TEM-1,beta-lactamase,P62593,0.499004,NO,230,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.154,-4.312,3.158,4.54336,0.01,E,B,0.75,-1.17,1.97,,50,HHA,-1.079,0.221079,0.00516841,0.499004 kka2_1:8_R38D,kka2_1:8_38,Kka2,kka2_1:8,P00552,0.499117,NO,38,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.207,-3.931,2.724,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.100394,0.00372499,0.499117 kka2_1:8_R38D,kka2_1:8_38,Kka2,kka2_1:8,P00552,0.499117,NO,38,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.207,-3.931,2.724,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.100394,0.00372499,0.499117 beta-lactamase_39_L79K,beta-lactamase_39_79,TEM-1,beta-lactamase_39,P62593,0.499255,NO,79,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.842,-3.679,2.837,,0.007,H,A,0.55,-0.16,0.823,,50.35,HHP,-1.44333,0.0495842,0.000947397,0.499255 beta-lactamase_2500_D83A,beta-lactamase_2500_83,TEM-1,beta-lactamase_2500,P62593,0.499303,NO,83,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.066,-3.208,2.142,,0.354,H,A,0.75,0.22,0.239,,48.95,HAH,-1.34733,0.361275,0.00205968,0.499303 WW_domain_F189H,WW_domain_189,Yap65,WW_domain,P46937,0.499401,NO,189,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.632,-4.34,2.708,5.47284,,,,,,6.165,,56.94,HHH,-1.454,0.153962,0.00308453,0.499401 beta-lactamase_625_L89R,beta-lactamase_625_89,TEM-1,beta-lactamase_625,P62593,0.49942,NO,89,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.096,-3.963,2.867,,0.168,T,A,0.55,0.63,1.599,,64.34,PHO,-1.75767,0.213352,0.00207068,0.49942 beta-lactamase_156_Y95R,beta-lactamase_156_95,TEM-1,beta-lactamase_156,P62593,0.499424,NO,95,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-1.715,-4.186,2.471,,0.122,,b,0.21,-0.37,2.341,,77.62,BHP,-2.16167,0.111618,0.00479449,0.499424 beta-lactamase_2500_A40N,beta-lactamase_2500_40,TEM-1,beta-lactamase_2500,P62593,0.499425,NO,40,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.402,-3.756,2.354,,0.155,S,B,0.46,0.21,0.953,,73.78,OHB,-1.40267,0.361275,0.00490026,0.499425 kka2_1:8_W91V,kka2_1:8_91,Kka2,kka2_1:8,P00552,0.499471,NO,91,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-1.178,-3.738,2.56,,0.077,E,B,1.51,0.27,2.51,,48.48,AHH,-1.51,0.100394,0.00358653,0.499471 kka2_1:8_W91V,kka2_1:8_91,Kka2,kka2_1:8,P00552,0.499471,NO,91,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-1.178,-3.738,2.56,,0.077,E,B,1.51,0.27,2.51,,48.48,AHH,-1.51,0.100394,0.00358653,0.499471 beta-lactamase_0_M127R,beta-lactamase_0_127,TEM-1,beta-lactamase_0,P62593,0.499544,NO,127,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-2.251,-2.722,0.471,,0.312,S,A,0.55,0.32,9.35,9.35,72.73,PHP,-1.40433,0.0500837,0.00437927,0.499544 kka2_1:4_R253Y,kka2_1:4_253,Kka2,kka2_1:4,P00552,0.499553,NO,253,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.356,-4.302,2.946,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.168804,0.0144195,0.499553 beta-lactamase_2500_T187Q,beta-lactamase_2500_187,TEM-1,beta-lactamase_2500,P62593,0.499573,NO,187,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.401,-4.004,2.603,,0.007,H,A,0.22,-1.19,3.91,,67.48,PPH,-1.69633,0.361275,0.00491782,0.499573 beta-lactamase_156_R59D,beta-lactamase_156_59,TEM-1,beta-lactamase_156,P62593,0.499585,NO,59,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.345,-3.634,2.289,,0.329,S,L,1.2,-0.09,2.995,,73.08,HBO,-2.24267,0.111618,0.00318082,0.499585 kka2_1:1_E17L,kka2_1:1_17,Kka2,kka2_1:1,P00552,0.499595,NO,17,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.154,-3.123,0.969,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.520039,0.00688738,0.499595 kka2_1:2_H139S,kka2_1:2_139,Kka2,kka2_1:2,P00552,0.499688,NO,139,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-2.809,-2.678,-0.131,,0.471,H,A,0.87,0.68,13.912,13.912,63.64,BBB,-2.22,0.295029,0.00734779,0.499688 kka2_1:4_R253V,kka2_1:4_253,Kka2,kka2_1:4,P00552,0.49975,NO,253,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.356,-3.689,2.333,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.168804,0.0144195,0.49975 kka2_1:8_D216T,kka2_1:8_216,Kka2,kka2_1:8,P00552,0.499872,NO,216,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.785,-3.493,2.708,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.100394,0.00229969,0.499872 kka2_1:8_D216T,kka2_1:8_216,Kka2,kka2_1:8,P00552,0.499872,NO,216,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.785,-3.493,2.708,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.100394,0.00229969,0.499872 kka2_1:1_R173G,kka2_1:1_173,Kka2,kka2_1:1,P00552,0.499884,NO,173,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.407,-3.552,1.145,,0.308,H,A,0.16,-0.13,14.756,14.756,65.53,HBH,-1.70533,0.520039,0.00784999,0.499884 Ubiquitin_A46L,Ubiquitin_46,Uba1,Ubiquitin,P0CG48,0.5,NO,46,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.77,-2.794,1.024,5.38761,0.398,T,L,2.34,-0.8,6.506,,51.09,HHO,-1.505,0.205827,0.000581142,0.5 Ubiquitin_F4A,Ubiquitin_4,Uba1,Ubiquitin,P0CG48,0.5,NO,4,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.534,-3.188,1.654,4.77459,0.059,E,B,,-0.46,,,,HHH,-1.504,0.205827,0.000805043,0.5 Ubiquitin_H68I,Ubiquitin_68,Uba1,Ubiquitin,P0CG48,0.5,NO,68,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-1.869,-3.029,1.16,4.81902,0.194,E,B,0.72,-1.02,21.325,21.325,65.11,HBH,-1.583,0.205827,0.000925438,0.5 Ubiquitin_K6F,Ubiquitin_6,Uba1,Ubiquitin,P0CG48,0.5,NO,6,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.093,-4.305,3.212,4.84211,0.35,E,B,1.82,-0.62,1.502,,71.82,HBP,-1.36133,0.205827,0.000784795,0.5 Ubiquitin_L67D,Ubiquitin_67,Uba1,Ubiquitin,P0CG48,0.5,NO,67,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.435,-3.927,2.492,4.92156,,E,B,1.19,-1.02,6.371,6.371,30.8,PHB,-1.628,0.205827,0.000482727,0.5 Ubiquitin_L69N,Ubiquitin_69,Uba1,Ubiquitin,P0CG48,0.5,NO,69,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.445,-3.958,2.513,4.75624,0.051,E,B,2.89,-0.94,7.106,,34.31,BHH,-1.72933,0.205827,0.000919136,0.5 Ubiquitin_V26R,Ubiquitin_26,Uba1,Ubiquitin,P0CG48,0.5,NO,26,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.321,-4.151,2.83,4.78447,,H,A,,-0.97,,,,PHB,-1.445,0.205827,0.000980269,0.5 kka2_1:2_A119T,kka2_1:2_119,Kka2,kka2_1:2,P00552,0.50007,NO,119,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.073,-3.309,2.236,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.295029,0.00441074,0.50007 kka2_1:8_D220T,kka2_1:8_220,Kka2,kka2_1:8,P00552,0.500098,NO,220,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.787,-3.448,2.661,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.100394,0.00158066,0.500098 kka2_1:8_D220T,kka2_1:8_220,Kka2,kka2_1:8,P00552,0.500098,NO,220,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.787,-3.448,2.661,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.100394,0.00158066,0.500098 beta-lactamase_156_M184G,beta-lactamase_156_184,TEM-1,beta-lactamase_156,P62593,0.500102,NO,184,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.593,-3.601,2.008,,,H,A,0.55,-0.87,1.671,,62.94,HHH,-1.41,0.111618,0.00356019,0.500102 beta-lactamase_A23W,beta-lactamase_23,TEM-1,beta-lactamase,P62593,0.500179,NO,23,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.548,-5.143,3.595,,,,,,,0.801,,93.01,HHB,-2.235,0.221079,0.00245563,0.500179 beta-lactamase_L100N,beta-lactamase_100,TEM-1,beta-lactamase,P62593,0.500179,NO,100,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.218,-4.207,2.989,5.60291,0.343,,B,1.3,0.13,1.173,,63.29,AHH,-1.23467,0.221079,0.00413885,0.500179 beta-lactamase_2500_R202Y,beta-lactamase_2500_202,TEM-1,beta-lactamase_2500,P62593,0.500264,NO,202,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.292,-4.182,2.89,,0.188,H,A,1.2,0.62,3.734,,77.62,PBP,-1.54767,0.361275,0.00321899,0.500264 beta-lactamase_625_L79C,beta-lactamase_625_79,TEM-1,beta-lactamase_625,P62593,0.500281,NO,79,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.842,-4.663,3.821,,0.007,H,A,0.55,-0.16,0.935,,50.35,HHP,-1.44333,0.213352,0.000947397,0.500281 beta-lactamase_2500_L223K,beta-lactamase_2500_223,TEM-1,beta-lactamase_2500,P62593,0.500296,NO,223,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.055,-3.742,2.687,,0.27,,B,0.55,0.09,1.334,,74.48,HHO,-1.35033,0.361275,0.00372793,0.500296 kka2_1:1_L158Q,kka2_1:1_158,Kka2,kka2_1:1,P00552,0.500298,NO,158,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.947,-4.338,2.391,,0.095,.,B,0.55,0.77,7.588,,63.64,AHA,-1.25333,0.520039,0.00529068,0.500298 kka2_1:1_G43V,kka2_1:1_43,Kka2,kka2_1:1,P00552,0.500313,NO,43,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.587,-3.838,2.251,,0.862,T,l,0.75,-0.67,2.247,,63.26,POB,-2.18533,0.520039,0.0071925,0.500313 beta-lactamase_2500_D83M,beta-lactamase_2500_83,TEM-1,beta-lactamase_2500,P62593,0.500314,NO,83,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.066,-4.912,3.846,,0.354,H,A,0.75,0.22,0.239,,48.95,HAH,-1.34733,0.361275,0.00205968,0.500314 kka2_1:1_A41V,kka2_1:1_41,Kka2,kka2_1:1,P00552,0.500317,NO,41,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.879,-2.914,1.035,,0.184,.,B,0.46,-0.96,18.207,18.207,64.39,PHP,-2.477,0.520039,0.00543332,0.500317 PSD95pdz3_G324H,PSD95pdz3_324,PSD95pdz3,PSD95pdz3,P31016,0.500346,NO,324,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.008,-4.362,3.354,4.98881,,,,,10.4525,,,,HOH,-1.293,0.0758425,0.00103462,0.500346 beta-lactamase_2500_K213P,beta-lactamase_2500_213,TEM-1,beta-lactamase_2500,P62593,0.500358,NO,213,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.81,-3.901,2.091,,0.67,,A,2.34,0.29,1.668,,67.83,ABH,-1.57767,0.361275,0.00610411,0.500358 kka2_1:1_Y22F,kka2_1:1_22,Kka2,kka2_1:1,P00552,0.500537,NO,22,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-1.583,-3.718,2.135,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.520039,0.00598977,0.500537 beta-lactamase_V117S,beta-lactamase_117,TEM-1,beta-lactamase,P62593,0.500727,NO,117,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.53,-3.729,2.199,5.33594,,H,A,1.19,-0.34,1.182,,65.03,PHB,-1.741,0.221079,0.00467906,0.500727 kka2_1:1_F20Y,kka2_1:1_20,Kka2,kka2_1:1,P00552,0.500744,NO,20,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-3.354,-4.354,1,,0.935,T,B,0.58,-0.41,1.657,,92.05,HHO,-1.992,0.520039,0.00701744,0.500744 beta-lactamase_2500_T269W,beta-lactamase_2500_269,TEM-1,beta-lactamase_2500,P62593,0.50079,NO,269,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.361275,0.00950944,0.50079 beta-lactamase_2500_G142S,beta-lactamase_2500_142,TEM-1,beta-lactamase_2500,P62593,0.500864,NO,142,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.707,-2.438,1.731,,0.034,,p,0.29,-0.64,1.883,,64.69,OOO,-0.834,0.361275,0.00060149,0.500864 beta-lactamase_156_L248S,beta-lactamase_156_248,TEM-1,beta-lactamase_156,P62593,0.500883,NO,248,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.111618,0.00428493,0.500883 kka2_1:8_L259R,kka2_1:8_259,Kka2,kka2_1:8,P00552,0.500925,NO,259,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.088,-3.982,2.894,,0.036,H,A,1.59,-0.15,1.83,,48.48,BHH,-1.15167,0.100394,0.0206964,0.500925 kka2_1:8_L259R,kka2_1:8_259,Kka2,kka2_1:8,P00552,0.500925,NO,259,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.088,-3.982,2.894,,0.036,H,A,1.59,-0.15,1.83,,48.48,BHH,-1.15167,0.100394,0.0206964,0.500925 beta-lactamase_39_A124E,beta-lactamase_39_124,TEM-1,beta-lactamase_39,P62593,0.500993,NO,124,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.181,-3.544,2.363,,,H,A,0.46,-0.9,1.367,,64.34,HHH,-1.152,0.0495842,0.00481399,0.500993 gb1_Y259E,gb1_259,gb1,gb1,P06654,0.500999,NO,259,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-1.78,-3.665,1.885,,,,,,,0.131,,11.83,PHH,-1.787,0.177985,0.00464313,0.500999 gb1_Y271N,gb1_271,gb1,gb1,P06654,0.500999,NO,271,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-1.181,-3.675,2.494,,,,,,,,,,PHA,-1.92933,0.177985,0.00236544,0.500999 beta-lactamase_2500_T69I,beta-lactamase_2500_69,TEM-1,beta-lactamase_2500,P62593,0.501096,NO,69,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-0.973,-3.64,2.667,,,G,A,0.22,-1.24,2.05,,93.01,PPH,-1.01833,0.361275,0.00127498,0.501096 beta-lactamase_2500_G76L,beta-lactamase_2500_76,TEM-1,beta-lactamase_2500,P62593,0.501137,NO,76,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.189,-3.521,2.332,,,H,A,0.29,-0.67,1.012,,67.83,OOH,-1.22267,0.361275,0.00476637,0.501137 kka2_1:8_D82L,kka2_1:8_82,Kka2,kka2_1:8,P00552,0.501264,NO,82,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.946,-3.65,1.704,,0.341,E,b,0.29,0.52,7.463,,63.64,HAH,-1.98,0.100394,0.00637516,0.501264 kka2_1:8_D82L,kka2_1:8_82,Kka2,kka2_1:8,P00552,0.501264,NO,82,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.946,-3.65,1.704,,0.341,E,b,0.29,0.52,7.463,,63.64,HAH,-1.98,0.100394,0.00637516,0.501264 kka2_1:8_W69P,kka2_1:8_69,Kka2,kka2_1:8,P00552,0.501292,NO,69,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-0.859,-4.356,3.497,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.100394,0.0012874,0.501292 kka2_1:8_W69P,kka2_1:8_69,Kka2,kka2_1:8,P00552,0.501292,NO,69,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-0.859,-4.356,3.497,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.100394,0.0012874,0.501292 kka2_1:8_Y244R,kka2_1:8_244,Kka2,kka2_1:8,P00552,0.501305,NO,244,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-0.775,-3.961,3.186,,0.066,H,A,1.25,-0.64,,,,HHO,-1.41267,0.100394,0.00453187,0.501305 kka2_1:8_Y244R,kka2_1:8_244,Kka2,kka2_1:8,P00552,0.501305,NO,244,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-0.775,-3.961,3.186,,0.066,H,A,1.25,-0.64,,,,HHO,-1.41267,0.100394,0.00453187,0.501305 beta-lactamase_R220M,beta-lactamase_220,TEM-1,beta-lactamase,P62593,0.501307,NO,220,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-0.942,-4.506,3.564,5.65995,0.295,I,A,0.68,-0.76,2.164,,74.48,HBP,-1.33633,0.221079,0.00232421,0.501307 kka2_1:2_R217C,kka2_1:2_217,Kka2,kka2_1:2,P00552,0.501315,NO,217,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.158,-5.113,3.955,,0.252,T,A,1.2,-0.59,0.381,,52.27,ABH,-1.127,0.295029,0.0047191,0.501315 beta-lactamase_2500_A215N,beta-lactamase_2500_215,TEM-1,beta-lactamase_2500,P62593,0.501356,NO,215,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.503,-3.679,2.176,,,,a,0.46,-0.93,3.516,,74.48,HHO,-1.42633,0.361275,0.00544007,0.501356 kka2_1:2_V80G,kka2_1:2_80,Kka2,kka2_1:2,P00552,0.501381,NO,80,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.144,-3.627,2.483,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.295029,0.00488211,0.501381 kka2_1:4_F203Y,kka2_1:4_203,Kka2,kka2_1:4,P00552,0.501476,NO,203,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-0.911,-3.189,2.278,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.168804,0.00318738,0.501476 kka2_1:8_Q219E,kka2_1:8_219,Kka2,kka2_1:8,P00552,0.501526,NO,219,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-0.93,-2.854,1.924,,0.088,H,A,0.4,-0.85,0.897,,50,HPA,-1.05167,0.100394,0.00237913,0.501526 kka2_1:8_Q219E,kka2_1:8_219,Kka2,kka2_1:8,P00552,0.501526,NO,219,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-0.93,-2.854,1.924,,0.088,H,A,0.4,-0.85,0.897,,50,HPA,-1.05167,0.100394,0.00237913,0.501526 beta-lactamase_N272M,beta-lactamase_272,TEM-1,beta-lactamase,P62593,0.501576,NO,272,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-1.127,-4.794,3.667,5.37826,0.081,H,A,0.09,-0.97,1.468,,63.64,BPB,-1.56333,0.221079,0.00545371,0.501576 kka2_1:8_I221N,kka2_1:8_221,Kka2,kka2_1:8,P00552,0.501601,NO,221,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.739,-4.276,2.537,,,H,A,1.52,-1.15,1.599,,71.59,AHH,-1.08367,0.100394,0.00945908,0.501601 kka2_1:8_I221N,kka2_1:8_221,Kka2,kka2_1:8,P00552,0.501601,NO,221,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.739,-4.276,2.537,,,H,A,1.52,-1.15,1.599,,71.59,AHH,-1.08367,0.100394,0.00945908,0.501601 kka2_1:8_E96W,kka2_1:8_96,Kka2,kka2_1:8,P00552,0.501675,NO,96,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.573,-5.436,2.863,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.100394,0.00369441,0.501675 kka2_1:8_E96W,kka2_1:8_96,Kka2,kka2_1:8,P00552,0.501675,NO,96,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.573,-5.436,2.863,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.100394,0.00369441,0.501675 beta-lactamase_2500_L146C,beta-lactamase_2500_146,TEM-1,beta-lactamase_2500,P62593,0.501732,NO,146,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.462,-4.847,3.385,,0.007,H,A,0.55,-0.56,1.578,,64.69,AHP,-1.656,0.361275,0.00474542,0.501732 kka2_1:8_P45Y,kka2_1:8_45,Kka2,kka2_1:8,P00552,0.50175,NO,45,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.774,-4.485,2.711,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.100394,0.00590481,0.50175 kka2_1:8_P45Y,kka2_1:8_45,Kka2,kka2_1:8,P00552,0.50175,NO,45,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.774,-4.485,2.711,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.100394,0.00590481,0.50175 beta-lactamase_2500_V78C,beta-lactamase_2500_78,TEM-1,beta-lactamase_2500,P62593,0.501835,NO,78,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.459,-4.812,3.353,,,H,A,0.44,-0.47,31.376,31.376,63.64,HHH,-1.17833,0.361275,0.00492501,0.501835 kka2_1:2_D159Y,kka2_1:2_159,Kka2,kka2_1:2,P00552,0.501857,NO,159,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.82,-4.45,3.63,,0.28,.,B,0.75,1.25,0.899,,48.11,HAA,-1.48333,0.295029,0.0030485,0.501857 beta-lactamase_2500_D212H,beta-lactamase_2500_212,TEM-1,beta-lactamase_2500,P62593,0.501862,NO,212,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.624,-4.56,2.936,,0.037,,b,0.75,-0.58,12.482,,74.48,HAB,-1.77667,0.361275,0.00644302,0.501862 kka2_1:1_P45S,kka2_1:1_45,Kka2,kka2_1:1,P00552,0.501942,NO,45,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.774,-2.464,0.69,,0.669,.,B,0.52,-0.76,4.882,,71.59,BOH,-2.152,0.520039,0.00590481,0.501942 kka2_1:2_D208N,kka2_1:2_208,Kka2,kka2_1:2,P00552,0.501951,NO,208,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.708,-3.251,2.543,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.295029,0.00212588,0.501951 kka2_1:2_D157F,kka2_1:2_157,Kka2,kka2_1:2,P00552,0.501975,NO,157,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.993,-4.394,3.401,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.295029,0.0042313,0.501975 beta-lactamase_39_F64K,beta-lactamase_39_64,TEM-1,beta-lactamase_39,P62593,0.501993,NO,64,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-0.841,-3.907,3.066,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.0495842,0.000947691,0.501993 kka2_1:2_G201A,kka2_1:2_201,Kka2,kka2_1:2,P00552,0.502086,NO,201,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.56,-3.247,1.687,,0.149,T,l,0.29,-0.57,16.092,16.092,52.65,POB,-1.92233,0.295029,0.00820117,0.502086 beta-lactamase_D161L,beta-lactamase_161,TEM-1,beta-lactamase,P62593,0.502134,NO,161,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.891,-3.777,2.886,5.12208,0.341,,A,0.23,-0.52,1.602,,61.19,HAB,-0.961333,0.221079,0.000897697,0.502134 beta-lactamase_2500_P250L,beta-lactamase_2500_250,TEM-1,beta-lactamase_2500,P62593,0.502143,NO,250,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.361275,0.00550899,0.502143 beta-lactamase_2500_M115V,beta-lactamase_2500_115,TEM-1,beta-lactamase_2500,P62593,0.502147,NO,115,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.389,-3.055,1.666,,0.019,E,B,0.55,0.08,3.261,,69.58,OHP,-1.25433,0.361275,0.0034337,0.502147 kka2_1:4_E142Y,kka2_1:4_142,Kka2,kka2_1:4,P00552,0.502206,NO,142,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.221,-4.391,2.17,,0.471,H,A,1.52,0.85,3.693,,65.53,HAB,-2.08033,0.168804,0.00748883,0.502206 kka2_1:4_I115M,kka2_1:4_115,Kka2,kka2_1:4,P00552,0.502255,NO,115,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.606,-2.756,1.15,,0.105,H,A,1.52,-1.18,9.996,9.996,65.53,PHH,-2.205,0.168804,0.00836567,0.502255 beta-lactamase_2500_Y103L,beta-lactamase_2500_103,TEM-1,beta-lactamase_2500,P62593,0.502256,NO,103,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-1.33,-3.402,2.072,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.361275,0.00443048,0.502256 beta-lactamase_2500_R257I,beta-lactamase_2500_257,TEM-1,beta-lactamase_2500,P62593,0.50236,NO,257,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.361275,0.00756629,0.50236 beta-lactamase_0_A215W,beta-lactamase_0_215,TEM-1,beta-lactamase_0,P62593,0.502379,NO,215,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.503,-5.336,3.833,,,,a,0.46,-0.93,0.494,,74.48,HHO,-1.42633,0.0500837,0.00544007,0.502379 kka2_1:8_M120A,kka2_1:8_120,Kka2,kka2_1:8,P00552,0.502388,NO,120,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-3.877,-3.104,-0.773,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.100394,0.00265808,0.502388 kka2_1:8_M120A,kka2_1:8_120,Kka2,kka2_1:8,P00552,0.502388,NO,120,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-3.877,-3.104,-0.773,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.100394,0.00265808,0.502388 kka2_1:4_V185T,kka2_1:4_185,Kka2,kka2_1:4,P00552,0.502396,NO,185,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.045,-3.363,2.318,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.168804,0.00367031,0.502396 beta-lactamase_625_D212W,beta-lactamase_625_212,TEM-1,beta-lactamase_625,P62593,0.502405,NO,212,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.624,-5.54,3.916,,0.037,,b,0.75,-0.58,1.516,,74.48,HAB,-1.77667,0.213352,0.00644302,0.502405 beta-lactamase_2500_L135E,beta-lactamase_2500_135,TEM-1,beta-lactamase_2500,P62593,0.502419,NO,135,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.002,-3.919,2.917,,0.117,H,A,0.55,-0.58,0.795,,43.71,PHH,-1.03767,0.361275,0.00244423,0.502419 PSD95pdz3_I336A,PSD95pdz3_336,PSD95pdz3,PSD95pdz3,P31016,0.502458,NO,336,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.63,-2.759,1.129,5.11321,,,,,13.6363,,,,OHH,-1.38733,0.0758425,0.000887923,0.502458 kka2_1:1_Y22D,kka2_1:1_22,Kka2,kka2_1:1,P00552,0.502502,NO,22,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-1.583,-3.909,2.326,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.520039,0.00598977,0.502502 kka2_1:1_S104I,kka2_1:1_104,Kka2,kka2_1:1,P00552,0.502552,NO,104,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.436,-3.864,2.428,,0.536,T,A,0.27,-1.11,5.49,,63.64,HPP,-1.91433,0.520039,0.00555207,0.502552 beta-lactamase_2500_I54N,beta-lactamase_2500_54,TEM-1,beta-lactamase_2500,P62593,0.502586,NO,54,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-2.838,-2.849,0.011,,0.669,E,B,0.48,-0.14,3.946,,73.78,BHH,-2.337,0.361275,0.00403589,0.502586 beta-lactamase_625_D48I,beta-lactamase_625_48,TEM-1,beta-lactamase_625,P62593,0.5027,NO,48,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.101,-4.047,2.946,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.213352,0.0027273,0.5027 kka2_1:1_A215V,kka2_1:1_215,Kka2,kka2_1:1,P00552,0.502701,NO,215,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.968,-3.282,2.314,,0.039,E,B,0.46,-0.59,0.754,,50.38,HHA,-1.00467,0.520039,0.00529129,0.502701 kka2_1:1_V84M,kka2_1:1_84,Kka2,kka2_1:1,P00552,0.502705,NO,84,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-2.279,-4.623,2.344,,0.258,E,B,0.44,1.03,3.484,,71.59,HHP,-2.337,0.520039,0.00724019,0.502705 kka2_1:2_R38D,kka2_1:2_38,Kka2,kka2_1:2,P00552,0.502709,NO,38,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.207,-3.931,2.724,,0.355,E,B,1.2,-1.13,6.872,6.872,52.27,HBH,-1.28567,0.295029,0.00372499,0.502709 kka2_1:2_L170F,kka2_1:2_170,Kka2,kka2_1:2,P00552,0.502713,NO,170,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.28,-3.877,2.597,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.295029,0.00730791,0.502713 kka2_1:4_A237C,kka2_1:4_237,Kka2,kka2_1:4,P00552,0.502796,NO,237,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.12,-4.796,2.676,,0.068,H,A,0.46,-0.71,2.444,,92.05,HHA,-2.10433,0.168804,0.012257,0.502796 beta-lactamase_A16D,beta-lactamase_16,TEM-1,beta-lactamase,P62593,0.502845,NO,16,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,,-3.632,1.697,,,,,,,,,,HHH,,0.221079,0.00245392,0.502845 beta-lactamase_2500_A123I,beta-lactamase_2500_123,TEM-1,beta-lactamase_2500,P62593,0.502883,NO,123,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.834,-3.433,2.599,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.361275,0.0010157,0.502883 kka2_1:1_A35C,kka2_1:1_35,Kka2,kka2_1:1,P00552,0.502899,NO,35,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.127,-3.602,1.475,,0.107,E,B,0.46,1.05,8.405,8.405,71.59,HHH,-1.31767,0.520039,0.00630016,0.502899 beta-lactamase_2500_L89S,beta-lactamase_2500_89,TEM-1,beta-lactamase_2500,P62593,0.502921,NO,89,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.096,-3.54,2.444,,0.168,T,A,0.55,0.63,2.066,,64.34,PHO,-1.75767,0.361275,0.00207068,0.502921 kka2_1:4_Y244V,kka2_1:4_244,Kka2,kka2_1:4,P00552,0.503002,NO,244,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-0.775,-3.332,2.557,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.168804,0.00453187,0.503002 kka2_1:2_D183S,kka2_1:2_183,Kka2,kka2_1:2,P00552,0.503049,NO,183,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.204,-3.317,2.113,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.295029,0.00426304,0.503049 beta-lactamase_2500_G52K,beta-lactamase_2500_52,TEM-1,beta-lactamase_2500,P62593,0.50309,NO,52,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.149,-3.631,2.482,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.361275,0.00340138,0.50309 kka2_1:4_R226A,kka2_1:4_226,Kka2,kka2_1:4,P00552,0.503113,NO,226,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.392,-3.272,1.88,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.168804,0.0108032,0.503113 kka2_1:4_R226V,kka2_1:4_226,Kka2,kka2_1:4,P00552,0.503113,NO,226,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.392,-3.893,2.501,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.168804,0.0108032,0.503113 beta-lactamase_2500_G194I,beta-lactamase_2500_194,TEM-1,beta-lactamase_2500,P62593,0.503114,NO,194,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.396,-4.133,2.737,,0.276,S,b,0.29,0.36,3.593,,67.83,POA,-1.832,0.361275,0.00392163,0.503114 beta-lactamase_156_I93G,beta-lactamase_156_93,TEM-1,beta-lactamase_156,P62593,0.503178,NO,93,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.401,-3.805,2.404,,0.128,E,B,0.48,0.44,1.524,,67.83,BHB,-1.873,0.111618,0.00527066,0.503178 kka2_1:2_L107T,kka2_1:2_107,Kka2,kka2_1:2,P00552,0.503314,NO,107,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.238,-2.585,1.347,,0.197,,B,1.59,-1.1,2.68,,71.59,BHH,-2.143,0.295029,0.00561937,0.503314 beta-lactamase_2500_G281T,beta-lactamase_2500_281,TEM-1,beta-lactamase_2500,P62593,0.503341,NO,281,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.361275,0.0406482,0.503341 kka2_1:1_D154V,kka2_1:1_154,Kka2,kka2_1:1,P00552,0.503345,NO,154,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.876,-3.815,2.939,,0.457,.,b,0.75,1.48,0.658,,52.65,HAP,-1.52467,0.520039,0.00292633,0.503345 beta-lactamase_V117Y,beta-lactamase_117,TEM-1,beta-lactamase,P62593,0.503393,NO,117,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.53,-2.958,1.428,5.33594,,H,A,1.19,-0.34,1.182,,65.03,PHB,-1.741,0.221079,0.00467906,0.503393 kka2_1:1_W69Q,kka2_1:1_69,Kka2,kka2_1:1,P00552,0.503406,NO,69,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-0.859,-4.151,3.292,,0.164,H,A,0.47,0.15,5.074,,38.64,PHH,-1.49967,0.520039,0.0012874,0.503406 beta-lactamase_625_I125A,beta-lactamase_625_125,TEM-1,beta-lactamase_625,P62593,0.503411,NO,125,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.441,-3.138,1.697,,,H,A,0.48,-0.7,2.034,,63.29,HHP,-1.248,0.213352,0.00383964,0.503411 kka2_1:2_G210R,kka2_1:2_210,Kka2,kka2_1:2,P00552,0.503417,NO,210,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.095,-4.007,2.912,,0.103,T,A,0.29,-0.62,0.271,,50,OOB,-0.966667,0.295029,0.00598378,0.503417 PSD95pdz3_A376N,PSD95pdz3_376,PSD95pdz3,PSD95pdz3,P31016,0.503424,NO,376,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.307,-3.58,2.273,4.72134,,,,,17.108,,,,HHH,-1.49567,0.0758425,0.000341232,0.503424 kka2_1:1_D33C,kka2_1:1_33,Kka2,kka2_1:1,P00552,0.503452,NO,33,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.186,-5.16,2.974,,0.561,S,A,0.75,3.35,2.568,,71.59,PAH,-1.306,0.520039,0.00633568,0.503452 kka2_1:1_T146W,kka2_1:1_146,Kka2,kka2_1:1,P00552,0.503453,NO,146,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.978,-5.546,2.568,,0.281,H,A,0.82,0.78,2.105,,92.05,BPB,-1.96833,0.520039,0.00606474,0.503453 beta-lactamase_625_E46W,beta-lactamase_625_46,TEM-1,beta-lactamase_625,P62593,0.503498,NO,46,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.94,-5.418,3.478,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.213352,0.00427568,0.503498 kka2_1:1_A56T,kka2_1:1_56,Kka2,kka2_1:1,P00552,0.503553,NO,56,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.083,-2.626,0.543,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.520039,0.00717715,0.503553 kka2_1:1_D62H,kka2_1:1_62,Kka2,kka2_1:1,P00552,0.503638,NO,62,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.591,-3.352,1.761,,0.262,H,A,0.75,0.08,10.048,10.048,64.39,PAA,-1.77833,0.520039,0.00744243,0.503638 beta-lactamase_V78Q,beta-lactamase_78,TEM-1,beta-lactamase,P62593,0.503709,NO,78,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.459,-4.26,2.801,4.79197,,H,A,0.96,-0.47,1.132,,63.64,HHH,-1.17833,0.221079,0.00492501,0.503709 kka2_1:8_E59F,kka2_1:8_59,Kka2,kka2_1:8,P00552,0.503719,NO,59,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-0.952,-4.364,3.412,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.100394,0.00280355,0.503719 kka2_1:8_E59F,kka2_1:8_59,Kka2,kka2_1:8,P00552,0.503719,NO,59,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-0.952,-4.364,3.412,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.100394,0.00280355,0.503719 beta-lactamase_2500_L49S,beta-lactamase_2500_49,TEM-1,beta-lactamase_2500,P62593,0.503781,NO,49,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.897,-2.417,0.52,,0.131,T,A,0.55,0.04,6.681,,64.69,AHP,-1.99233,0.361275,0.00401477,0.503781 kka2_1:8_I221P,kka2_1:8_221,Kka2,kka2_1:8,P00552,0.503845,NO,221,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.739,-4.232,2.493,,,H,A,1.52,-1.15,1.599,,71.59,AHH,-1.08367,0.100394,0.00945908,0.503845 kka2_1:8_I221P,kka2_1:8_221,Kka2,kka2_1:8,P00552,0.503845,NO,221,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.739,-4.232,2.493,,,H,A,1.52,-1.15,1.599,,71.59,AHH,-1.08367,0.100394,0.00945908,0.503845 beta-lactamase_2500_T116P,beta-lactamase_2500_116,TEM-1,beta-lactamase_2500,P62593,0.503917,NO,116,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.28,-3.831,2.551,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.361275,0.00336175,0.503917 beta-lactamase_156_V117K,beta-lactamase_156_117,TEM-1,beta-lactamase_156,P62593,0.503943,NO,117,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.53,-3.844,2.314,,,H,A,0.44,-0.34,1.182,,65.03,PHB,-1.741,0.111618,0.00467906,0.503943 beta-lactamase_L205A,beta-lactamase_205,TEM-1,beta-lactamase,P62593,0.503955,NO,205,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.922,-3.132,2.21,5.67023,,H,A,1.3,-0.46,0.678,,42.31,PHH,-1.57767,0.221079,0.00255802,0.503955 beta-lactamase_L120S,beta-lactamase_120,TEM-1,beta-lactamase,P62593,0.503963,NO,120,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.044,-3.66,2.616,5.11974,,H,A,1.3,-1.13,1.988,,64.69,AHO,-1.13633,0.221079,0.00143563,0.503963 kka2_1:2_L92W,kka2_1:2_92,Kka2,kka2_1:2,P00552,0.503982,NO,92,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.893,-5.185,4.292,,0.007,E,B,1.59,-0.19,1.447,,63.26,HHH,-0.962,0.295029,0.00307177,0.503982 kka2_1:2_V97A,kka2_1:2_97,Kka2,kka2_1:2,P00552,0.504023,NO,97,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.453,-2.616,1.163,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.295029,0.00737869,0.504023 kka2_1:2_R38I,kka2_1:2_38,Kka2,kka2_1:2,P00552,0.50404,NO,38,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.207,-3.515,2.308,,0.355,E,B,1.2,-1.13,6.872,6.872,52.27,HBH,-1.28567,0.295029,0.00372499,0.50404 beta-lactamase_2500_T178C,beta-lactamase_2500_178,TEM-1,beta-lactamase_2500,P62593,0.504148,NO,178,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-0.791,-4.637,3.846,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.361275,0.000684366,0.504148 beta-lactamase_A246D,beta-lactamase_246,TEM-1,beta-lactamase,P62593,0.504212,NO,246,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.121,-4.086,1.965,4.78979,0.01,E,B,0.52,-1.01,1.26,,73.78,HHH,-1.55633,0.221079,0.00569458,0.504212 kka2_1:8_V214E,kka2_1:8_214,Kka2,kka2_1:8,P00552,0.504214,NO,214,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.261,-3.897,2.636,,0.117,E,B,1.48,-0.31,1.859,,64.39,OHH,-0.941667,0.100394,0.00692782,0.504214 kka2_1:8_V214E,kka2_1:8_214,Kka2,kka2_1:8,P00552,0.504214,NO,214,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.261,-3.897,2.636,,0.117,E,B,1.48,-0.31,1.859,,64.39,OHH,-0.941667,0.100394,0.00692782,0.504214 beta-lactamase_T158C,beta-lactamase_158,TEM-1,beta-lactamase,P62593,0.504326,NO,158,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.116,-4.748,3.632,5.32011,0.036,,B,0.98,-0.85,2.755,,69.58,HPB,-1.269,0.221079,0.00341825,0.504326 kka2_1:4_L39P,kka2_1:4_39,Kka2,kka2_1:4,P00552,0.504386,NO,39,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.223,-4.188,2.965,,,E,B,0.55,-1.21,1.998,,71.59,BHP,-1.69167,0.168804,0.00493618,0.504386 kka2_1:2_S32C,kka2_1:2_32,Kka2,kka2_1:2,P00552,0.504463,NO,32,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-0.804,-4.665,3.861,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.295029,0.00149998,0.504463 kka2_1:2_S32Y,kka2_1:2_32,Kka2,kka2_1:2,P00552,0.504463,NO,32,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-0.804,-4.191,3.387,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.295029,0.00149998,0.504463 beta-lactamase_2500_L47F,beta-lactamase_2500_47,TEM-1,beta-lactamase_2500,P62593,0.504471,NO,47,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.876,-3.101,1.225,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.361275,0.00439844,0.504471 beta-lactamase_D231W,beta-lactamase_231,TEM-1,beta-lactamase,P62593,0.504539,NO,231,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.816,-5.545,4.729,5.06651,,E,B,1.22,-1.06,0.319,,65.38,HAB,-0.994,0.221079,0.00107395,0.504539 kka2_1:2_P109M,kka2_1:2_109,Kka2,kka2_1:2,P00552,0.504573,NO,109,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.412,-4.773,3.361,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.295029,0.0070929,0.504573 kka2_1:2_W91D,kka2_1:2_91,Kka2,kka2_1:2,P00552,0.504583,NO,91,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-1.178,-4.116,2.938,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.295029,0.00358653,0.504583 kka2_1:2_L19P,kka2_1:2_19,Kka2,kka2_1:2,P00552,0.504623,NO,19,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.254,-4.281,3.027,,0.08,T,A,0.55,-0.26,17.165,17.165,65.53,BHH,-2.221,0.295029,0.00620703,0.504623 kka2_1:1_Q61P,kka2_1:1_61,Kka2,kka2_1:1,P00552,0.504697,NO,61,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.982,-1.818,-1.164,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.520039,0.00612092,0.504697 beta-lactamase_L218Q,beta-lactamase_218,TEM-1,beta-lactamase,P62593,0.504715,NO,218,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.391,-3.953,2.562,4.88972,,I,b,2.89,-0.53,12.788,12.788,74.48,OHH,-1.58867,0.221079,0.00618274,0.504715 kka2_1:1_Q42I,kka2_1:1_42,Kka2,kka2_1:1,P00552,0.504729,NO,42,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.907,-4.147,1.24,,1.044,T,B,0.4,-0.8,2.792,,71.59,HPO,-2.12433,0.520039,0.00679212,0.504729 kka2_1:4_A119E,kka2_1:4_119,Kka2,kka2_1:4,P00552,0.504753,NO,119,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.073,-3.557,2.484,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.168804,0.00441074,0.504753 beta-lactamase_39_D177T,beta-lactamase_39_177,TEM-1,beta-lactamase_39,P62593,0.504826,NO,177,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.967,-3.465,2.498,,0.006,T,L,0.75,-1.02,3.536,,64.69,BAP,-0.873667,0.0495842,0.000864022,0.504826 beta-lactamase_156_G243T,beta-lactamase_156_243,TEM-1,beta-lactamase_156,P62593,0.504852,NO,243,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.532,,,,,E,B,0.77,-1.24,2.866,,50,BOH,-1.46867,0.111618,0.00464034,0.504852 beta-lactamase_156_T27W,beta-lactamase_156_27,TEM-1,beta-lactamase_156,P62593,0.504979,NO,27,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.905,-5.314,3.409,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.111618,0.00306559,0.504979 beta-lactamase_R220L,beta-lactamase_220,TEM-1,beta-lactamase,P62593,0.504987,NO,220,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-0.942,-3.356,2.414,5.65995,0.295,I,A,0.68,-0.76,2.164,,74.48,HBP,-1.33633,0.221079,0.00232421,0.504987 kka2_1:1_E86R,kka2_1:1_86,Kka2,kka2_1:1,P00552,0.505021,NO,86,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.86,-3.888,2.028,,0.369,.,B,1.04,1.92,18.506,18.506,63.26,PAH,-1.98067,0.520039,0.00642858,0.505021 beta-lactamase_E119Y,beta-lactamase_119,TEM-1,beta-lactamase,P62593,0.505066,NO,119,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.412,-4.336,2.924,5.33349,0.358,H,A,1.52,0.51,1.983,,63.99,BAH,-1.623,0.221079,0.00386966,0.505066 beta-lactamase_V117H,beta-lactamase_117,TEM-1,beta-lactamase,P62593,0.505066,NO,117,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.53,-4.89,3.36,5.33594,,H,A,1.19,-0.34,1.182,,65.03,PHB,-1.741,0.221079,0.00467906,0.505066 kka2_1:2_Y244W,kka2_1:2_244,Kka2,kka2_1:2,P00552,0.505131,NO,244,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-0.775,-4.226,3.451,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.295029,0.00453187,0.505131 kka2_1:1_R121C,kka2_1:1_121,Kka2,kka2_1:1,P00552,0.505138,NO,121,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.552,-5.157,3.605,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.520039,0.00523326,0.505138 kka2_1:8_G205L,kka2_1:8_205,Kka2,kka2_1:8,P00552,0.50518,NO,205,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.596,-3.836,3.24,,,E,b,0.75,-1.05,,,,POH,-1.09933,0.100394,0.00221855,0.50518 kka2_1:8_G205L,kka2_1:8_205,Kka2,kka2_1:8,P00552,0.50518,NO,205,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.596,-3.836,3.24,,,E,b,0.75,-1.05,,,,POH,-1.09933,0.100394,0.00221855,0.50518 kka2_1:1_S40E,kka2_1:1_40,Kka2,kka2_1:1,P00552,0.505201,NO,40,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.645,-2.141,-0.504,,0.32,E,B,0.27,-0.9,25.997,25.997,71.59,HPH,-1.91567,0.520039,0.00693477,0.505201 kka2_1:4_E182S,kka2_1:4_182,Kka2,kka2_1:4,P00552,0.505252,NO,182,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.516,-3.382,1.866,,0.326,.,B,1.04,0.75,4.755,,65.53,OAA,-1.806,0.168804,0.00641548,0.505252 beta-lactamase_2500_V260S,beta-lactamase_2500_260,TEM-1,beta-lactamase_2500,P62593,0.505421,NO,260,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.361275,0.00471757,0.505421 beta-lactamase_2500_P105R,beta-lactamase_2500_105,TEM-1,beta-lactamase_2500,P62593,0.50543,NO,105,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.813,-3.93,3.117,,0.226,T,A,0.52,0.8,3.1,,63.29,POH,-1.01533,0.361275,0.0011981,0.50543 kka2_1:1_R258H,kka2_1:1_258,Kka2,kka2_1:1,P00552,0.505459,NO,258,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.626,-4.623,2.997,,0.316,H,A,1.2,-0.85,7.485,7.485,53.03,HBH,-1.25933,0.520039,0.00983174,0.505459 kka2_1:8_V185Y,kka2_1:8_185,Kka2,kka2_1:8,P00552,0.50555,NO,185,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.045,-4.096,3.051,,0.058,E,B,1.48,-0.49,1.234,,46.97,HHH,-1.184,0.100394,0.00367031,0.50555 kka2_1:8_V185Y,kka2_1:8_185,Kka2,kka2_1:8,P00552,0.50555,NO,185,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.045,-4.096,3.051,,0.058,E,B,1.48,-0.49,1.234,,46.97,HHH,-1.184,0.100394,0.00367031,0.50555 kka2_1:1_G21E,kka2_1:1_21,Kka2,kka2_1:1,P00552,0.50558,NO,21,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.368,-3.414,2.046,,0.586,T,l,0.29,-0.75,10.291,10.291,71.59,HOH,-2.10167,0.520039,0.00709648,0.50558 beta-lactamase_156_A123K,beta-lactamase_156_123,TEM-1,beta-lactamase_156,P62593,0.505701,NO,123,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.834,-3.506,2.672,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.111618,0.0010157,0.505701 kka2_1:1_Q26Y,kka2_1:1_26,Kka2,kka2_1:1,P00552,0.505746,NO,26,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.18,-4.333,2.153,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.520039,0.00708962,0.505746 kka2_1:1_A255V,kka2_1:1_255,Kka2,kka2_1:1,P00552,0.50577,NO,255,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.715,-3.655,1.94,,0.466,H,A,0.46,-0.52,0.946,,65.53,HHH,-1.71267,0.520039,0.0126809,0.50577 kka2_1:2_R140E,kka2_1:2_140,Kka2,kka2_1:2,P00552,0.505774,NO,140,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.351,-3.33,1.979,,0.12,H,A,1.2,0.2,0.352,,53.03,BBH,-1.885,0.295029,0.00430167,0.505774 kka2_1:1_L81Q,kka2_1:1_81,Kka2,kka2_1:1,P00552,0.505863,NO,81,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.427,-3.189,1.762,,0.46,E,A,0.55,-0.14,0.374,,63.64,HHA,-1.50567,0.520039,0.00805839,0.505863 kka2_1:2_W69T,kka2_1:2_69,Kka2,kka2_1:2,P00552,0.505952,NO,69,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-0.859,-3.698,2.839,,0.164,H,A,0.47,0.15,5.074,,38.64,PHH,-1.49967,0.295029,0.0012874,0.505952 kka2_1:2_V153G,kka2_1:2_153,Kka2,kka2_1:2,P00552,0.505987,NO,153,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.092,-3.674,2.582,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.295029,0.00501119,0.505987 beta-lactamase_2500_E87G,beta-lactamase_2500_87,TEM-1,beta-lactamase_2500,P62593,0.505993,NO,87,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.421,-3.541,2.12,,0.048,,B,1.04,0.92,17.923,17.923,64.69,PAP,-1.969,0.361275,0.00337888,0.505993 kka2_1:1_P249L,kka2_1:1_249,Kka2,kka2_1:1,P00552,0.506016,NO,249,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.867,-2.363,0.496,,0.406,.,B,0.52,-0.01,8.037,8.037,92.05,HOA,-1.66867,0.520039,0.011045,0.506016 beta-lactamase_2500_G154V,beta-lactamase_2500_154,TEM-1,beta-lactamase_2500,P62593,0.506021,NO,154,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.823,-3.725,2.902,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.361275,0.00180205,0.506021 kka2_1:1_S114I,kka2_1:1_114,Kka2,kka2_1:1,P00552,0.50604,NO,114,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.527,-3.933,1.406,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.520039,0.00705262,0.50604 beta-lactamase_2500_D212M,beta-lactamase_2500_212,TEM-1,beta-lactamase_2500,P62593,0.506135,NO,212,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.624,-4.83,3.206,,0.037,,b,0.75,-0.58,12.482,,74.48,HAB,-1.77667,0.361275,0.00644302,0.506135 kka2_1:8_D261S,kka2_1:8_261,Kka2,kka2_1:8,P00552,0.506286,NO,261,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.708,-3.189,2.481,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.100394,0.0224846,0.506286 kka2_1:8_D261S,kka2_1:8_261,Kka2,kka2_1:8,P00552,0.506286,NO,261,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.708,-3.189,2.481,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.100394,0.0224846,0.506286 beta-lactamase_2500_N98C,beta-lactamase_2500_98,TEM-1,beta-lactamase_2500,P62593,0.506321,NO,98,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-2.973,-5.105,2.132,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.361275,0.00505389,0.506321 beta-lactamase_2500_G142A,beta-lactamase_2500_142,TEM-1,beta-lactamase_2500,P62593,0.506353,NO,142,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.707,-2.85,2.143,,0.034,,p,0.29,-0.64,1.883,,64.69,OOO,-0.834,0.361275,0.00060149,0.506353 kka2_1:1_I221N,kka2_1:1_221,Kka2,kka2_1:1,P00552,0.506388,NO,221,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.739,-4.276,2.537,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.520039,0.00945908,0.506388 kka2_1:1_G10L,kka2_1:1_10,Kka2,kka2_1:1,P00552,0.506393,NO,10,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.921,-3.61,1.689,,,,,,,1.862,,71.59,HOP,-2.10733,0.520039,0.00289233,0.506393 kka2_1:8_N195R,kka2_1:8_195,Kka2,kka2_1:8,P00552,0.506426,NO,195,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-0.836,-3.572,2.736,,0.037,G,A,0.43,-1.36,1.108,,48.11,OPH,-1.26567,0.100394,0.00276134,0.506426 kka2_1:8_N195R,kka2_1:8_195,Kka2,kka2_1:8,P00552,0.506426,NO,195,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-0.836,-3.572,2.736,,0.037,G,A,0.43,-1.36,1.108,,48.11,OPH,-1.26567,0.100394,0.00276134,0.506426 kka2_1:8_G189R,kka2_1:8_189,Kka2,kka2_1:8,P00552,0.506512,NO,189,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.596,-3.961,3.365,,0.034,S,l,0.75,-0.99,,,,BOA,-0.739,0.100394,0.00253688,0.506512 kka2_1:8_G189R,kka2_1:8_189,Kka2,kka2_1:8,P00552,0.506512,NO,189,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.596,-3.961,3.365,,0.034,S,l,0.75,-0.99,,,,BOA,-0.739,0.100394,0.00253688,0.506512 kka2_1:2_E235L,kka2_1:2_235,Kka2,kka2_1:2,P00552,0.506555,NO,235,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.955,-3.621,1.666,,0.631,H,A,1.04,0.12,26.048,26.048,65.53,OAH,-2.07267,0.295029,0.0102806,0.506555 beta-lactamase_2500_T27Q,beta-lactamase_2500_27,TEM-1,beta-lactamase_2500,P62593,0.506614,NO,27,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.905,-3.929,2.024,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.361275,0.00306559,0.506614 kka2_1:2_L184C,kka2_1:2_184,Kka2,kka2_1:2,P00552,0.506641,NO,184,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.496,-5.02,3.524,,0.489,E,B,0.55,-0.06,14.044,14.044,63.26,AHH,-1.24833,0.295029,0.00518742,0.506641 kka2_1:2_L184T,kka2_1:2_184,Kka2,kka2_1:2,P00552,0.506641,NO,184,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.496,-3.677,2.181,,0.489,E,B,0.55,-0.06,14.044,14.044,63.26,AHH,-1.24833,0.295029,0.00518742,0.506641 kka2_1:1_A71V,kka2_1:1_71,Kka2,kka2_1:1,P00552,0.50667,NO,71,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.824,-3.693,1.869,,0.553,H,A,0.46,0.08,9.788,,64.39,HHP,-1.74033,0.520039,0.00727707,0.50667 kka2_1:4_D82K,kka2_1:4_82,Kka2,kka2_1:4,P00552,0.506771,NO,82,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.946,-3.004,1.058,,0.341,E,b,0.75,0.52,11.923,11.923,63.64,HAH,-1.98,0.168804,0.00637516,0.506771 beta-lactamase_2500_R242T,beta-lactamase_2500_242,TEM-1,beta-lactamase_2500,P62593,0.506901,NO,242,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.361275,0.00452879,0.506901 PSD95pdz3_V328E,PSD95pdz3_328,PSD95pdz3,PSD95pdz3,P31016,0.506902,NO,328,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.465,-3.347,1.882,5.28275,,,,,16.8775,,,,HHO,-1.36767,0.0758425,0.000986706,0.506902 beta-lactamase_625_A123Q,beta-lactamase_625_123,TEM-1,beta-lactamase_625,P62593,0.506919,NO,123,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.834,-3.948,3.114,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.213352,0.0010157,0.506919 beta-lactamase_G279N,beta-lactamase_279,TEM-1,beta-lactamase,P62593,0.506946,NO,279,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.038,-3.525,2.487,4.53882,,H,A,0.46,-0.97,3.066,,62.59,HOH,-1.36467,0.221079,0.0192826,0.506946 beta-lactamase_156_L146E,beta-lactamase_156_146,TEM-1,beta-lactamase_156,P62593,0.50696,NO,146,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.462,-3.93,2.468,,0.007,H,A,0.55,-0.56,1.578,,64.69,AHP,-1.656,0.111618,0.00474542,0.50696 beta-lactamase_156_L150E,beta-lactamase_156_150,TEM-1,beta-lactamase_156,P62593,0.506998,NO,150,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.326,-3.822,2.496,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.111618,0.00463171,0.506998 kka2_1:1_D159H,kka2_1:1_159,Kka2,kka2_1:1,P00552,0.507092,NO,159,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.82,-4.547,3.727,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.520039,0.0030485,0.507092 kka2_1:2_E111P,kka2_1:2_111,Kka2,kka2_1:2,P00552,0.507141,NO,111,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.28,-4.066,1.786,,0.155,H,A,1.52,-1.14,2.792,,65.53,HAB,-2.27833,0.295029,0.00746789,0.507141 kka2_1:4_D159A,kka2_1:4_159,Kka2,kka2_1:4,P00552,0.507228,NO,159,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.82,-3.286,2.466,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.168804,0.0030485,0.507228 kka2_1:2_T72V,kka2_1:2_72,Kka2,kka2_1:2,P00552,0.507237,NO,72,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.38,-3.703,1.323,,0.784,H,A,0.82,0.29,6.463,,65.53,HPP,-2.238,0.295029,0.00750756,0.507237 kka2_1:4_N58Y,kka2_1:4_58,Kka2,kka2_1:4,P00552,0.50724,NO,58,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-2.641,-4.48,1.839,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.168804,0.00793425,0.50724 kka2_1:2_D90V,kka2_1:2_90,Kka2,kka2_1:2,P00552,0.507278,NO,90,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.459,-3.794,1.335,,0.104,E,B,0.75,0.73,6.085,,64.39,BAH,-1.72833,0.295029,0.00583842,0.507278 kka2_1:4_D216V,kka2_1:4_216,Kka2,kka2_1:4,P00552,0.507317,NO,216,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.785,-3.805,3.02,,0.018,E,B,0.75,-0.51,0.112,,19.32,HAB,-0.970333,0.168804,0.00229969,0.507317 beta-lactamase_2500_V106D,beta-lactamase_2500_106,TEM-1,beta-lactamase_2500,P62593,0.507326,NO,106,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.218,-4.056,2.838,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.361275,0.00304168,0.507326 beta-lactamase_2500_T69H,beta-lactamase_2500_69,TEM-1,beta-lactamase_2500,P62593,0.507435,NO,69,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-0.973,-4.716,3.743,,,G,A,0.22,-1.24,2.05,,93.01,PPH,-1.01833,0.361275,0.00127498,0.507435 PSD95pdz3_A347L,PSD95pdz3_347,PSD95pdz3,PSD95pdz3,P31016,0.50745,NO,347,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.307,-2.815,1.508,4.89689,,,,,15.176,,,,OHA,-1.269,0.0758425,0.00074525,0.50745 Pab1_F146R,Pab1_146,Pab1,Pab1,P04147,0.507497,NO,146,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.149,-3.975,2.826,,0.006,H,A,,0.75,,,,PHP,-1.161,0.175299,0.000329265,0.507497 kka2_1:2_K112P,kka2_1:2_112,Kka2,kka2_1:2,P00552,0.507519,NO,112,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-2.491,-4.121,1.63,,0.076,H,A,2.34,-1.37,23.433,23.433,56.06,ABH,-2.00133,0.295029,0.00645389,0.507519 kka2_1:8_V185H,kka2_1:8_185,Kka2,kka2_1:8,P00552,0.507544,NO,185,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.045,-4.98,3.935,,0.058,E,B,1.48,-0.49,1.234,,46.97,HHH,-1.184,0.100394,0.00367031,0.507544 kka2_1:8_V185H,kka2_1:8_185,Kka2,kka2_1:8,P00552,0.507544,NO,185,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.045,-4.98,3.935,,0.058,E,B,1.48,-0.49,1.234,,46.97,HHH,-1.184,0.100394,0.00367031,0.507544 beta-lactamase_N130T,beta-lactamase_130,TEM-1,beta-lactamase,P62593,0.507545,NO,130,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-0.798,-3.196,2.398,5.26686,0.069,H,A,1.08,-0.74,,,,APP,-0.980667,0.221079,0.000683376,0.507545 kka2_1:1_E199K,kka2_1:1_199,Kka2,kka2_1:1,P00552,0.507557,NO,199,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.234,-3.055,0.821,,0.508,E,B,1.04,-0.43,3.012,,65.53,HAP,-2.133,0.520039,0.00854122,0.507557 kka2_1:1_D227H,kka2_1:1_227,Kka2,kka2_1:1,P00552,0.507558,NO,227,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.758,-4.528,2.77,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.520039,0.00745029,0.507558 kka2_1:1_F264V,kka2_1:1_264,Kka2,kka2_1:1,P00552,0.507724,NO,264,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.02,-3.361,2.341,,0.296,.,?,0.58,0.02,2.303,,71.59,HHNA,-0.9655,0.520039,,0.507724 kka2_1:1_A78S,kka2_1:1_78,Kka2,kka2_1:1,P00552,0.507818,NO,78,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.744,-3.309,1.565,,0.078,.,B,0.46,-0.53,0.206,,56.06,OHH,-1.863,0.520039,0.00457299,0.507818 kka2_1:1_A25R,kka2_1:1_25,Kka2,kka2_1:1,P00552,0.507862,NO,25,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.496,-2.407,-0.089,,0.427,E,B,0.46,-0.47,6.872,6.872,65.53,HHP,-2.15167,0.520039,0.00595636,0.507862 beta-lactamase_2500_T158F,beta-lactamase_2500_158,TEM-1,beta-lactamase_2500,P62593,0.507963,NO,158,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.116,-4.177,3.061,,0.036,,B,0.22,-0.85,1.344,,69.58,HPB,-1.269,0.361275,0.00341825,0.507963 Pab1_F170C,Pab1_170,Pab1,Pab1,P04147,0.508025,NO,170,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.269,-4.733,3.464,,0.331,E,B,0.87,-1.31,2.061,,79.72,OHH,-1.06367,0.175299,0.000540225,0.508025 kka2_1:1_G99S,kka2_1:1_99,Kka2,kka2_1:1,P00552,0.508043,NO,99,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.596,-3.189,2.593,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.520039,0.00186055,0.508043 kka2_1:1_Q155F,kka2_1:1_155,Kka2,kka2_1:1,P00552,0.50806,NO,155,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.606,-4.366,1.76,,0.525,T,A,0.4,1.49,4.415,,63.64,APA,-1.726,0.520039,0.00641853,0.50806 Ubiquitin_I61S,Ubiquitin_61,Uba1,Ubiquitin,P0CG48,0.508065,NO,61,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.514,-2.804,1.29,5.19922,0.038,,B,1,-0.76,1.953,,24.53,PHP,-1.70833,0.205827,0.000738268,0.508065 kka2_1:1_L152Q,kka2_1:1_152,Kka2,kka2_1:1,P00552,0.508071,NO,152,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.521,-2.735,1.214,,0.547,.,A,0.55,1.36,1.589,,63.64,OHH,-1.162,0.520039,0.00674868,0.508071 kka2_1:4_F240R,kka2_1:4_240,Kka2,kka2_1:4,P00552,0.508113,NO,240,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-0.911,-4.185,3.274,,,H,A,0.58,-1.21,5.798,,50.38,BHH,-1.67267,0.168804,0.00552543,0.508113 kka2_1:2_L102D,kka2_1:2_102,Kka2,kka2_1:2,P00552,0.508122,NO,102,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.804,-4.17,3.366,,,T,A,1.59,-1.17,4.258,,42.42,AHH,-1.398,0.295029,0.00201332,0.508122 kka2_1:4_Y218S,kka2_1:4_218,Kka2,kka2_1:4,P00552,0.508185,NO,218,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-1.438,-3.656,2.218,,0.122,H,A,0.21,-0.69,1.022,,56.06,BHP,-1.17533,0.168804,0.0126098,0.508185 Pab1_I130S,Pab1_130,Pab1,Pab1,P04147,0.50822,NO,130,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.212,-3.428,2.216,,,E,B,1.23,0.01,,,,HHB,-1.188,0.175299,0.000351112,0.50822 kka2_1:1_E182G,kka2_1:1_182,Kka2,kka2_1:1,P00552,0.508319,NO,182,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.516,-2.588,1.072,,0.326,,B,1.52,0.75,14.547,14.547,65.53,OAA,-1.806,0.520039,0.00641548,0.508319 beta-lactamase_2500_L197H,beta-lactamase_2500_197,TEM-1,beta-lactamase_2500,P62593,0.508451,NO,197,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.853,-4.903,4.05,,0.007,S,B,0.55,0.33,2.421,,60.14,HHP,-1.833,0.361275,0.00144602,0.508451 beta-lactamase_0_P224Q,beta-lactamase_0_224,TEM-1,beta-lactamase_0,P62593,0.508461,NO,224,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.893,-3.868,2.975,,0.383,,B,0.52,-0.3,3.587,,74.48,HOH,-1.26433,0.0500837,0.00189564,0.508461 kka2_1:2_W15Q,kka2_1:2_15,Kka2,kka2_1:2,P00552,0.508482,NO,15,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-1.392,-4.279,2.887,,0.01,G,A,0.47,0.15,2.586,,52.27,HHH,-2.10533,0.295029,0.00585505,0.508482 kka2_1:4_M197F,kka2_1:4_197,Kka2,kka2_1:4,P00552,0.508488,NO,197,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.707,-3.862,2.155,,0.121,E,B,0.55,-1.19,0.415,,65.53,HHH,-1.847,0.168804,0.00921295,0.508488 beta-lactamase_156_A132T,beta-lactamase_156_132,TEM-1,beta-lactamase_156,P62593,0.508553,NO,132,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.9,-3.22,2.32,,,H,A,0.46,-0.93,10.621,,64.69,PHH,-1.138,0.111618,0.000962524,0.508553 beta-lactamase_V72G,beta-lactamase_72,TEM-1,beta-lactamase,P62593,0.508581,NO,72,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.658,-3.477,1.819,5.80324,,H,A,2.78,-1.03,2.964,,65.73,BHH,-1.32167,0.221079,0.00501194,0.508581 kka2_1:1_R122H,kka2_1:1_122,Kka2,kka2_1:1,P00552,0.508596,NO,122,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.175,-3.287,1.112,,0.487,H,A,1.2,0.26,1.356,,71.59,BBH,-1.53833,0.520039,0.00736512,0.508596 kka2_1:8_G30H,kka2_1:8_30,Kka2,kka2_1:8,P00552,0.508601,NO,30,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.596,-4.708,4.112,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.100394,0.00159208,0.508601 kka2_1:8_G30H,kka2_1:8_30,Kka2,kka2_1:8,P00552,0.508601,NO,30,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.596,-4.708,4.112,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.100394,0.00159208,0.508601 beta-lactamase_2500_M115A,beta-lactamase_2500_115,TEM-1,beta-lactamase_2500,P62593,0.508612,NO,115,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.389,-2.535,1.146,,0.019,E,B,0.55,0.08,3.261,,69.58,OHP,-1.25433,0.361275,0.0034337,0.508612 beta-lactamase_2500_L38V,beta-lactamase_2500_38,TEM-1,beta-lactamase_2500,P62593,0.508645,NO,38,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.343,-2.209,0.866,,0.088,H,A,0.55,0.2,2.71,,64.34,PHO,-1.78033,0.361275,0.00373244,0.508645 beta-lactamase_2500_L205V,beta-lactamase_2500_205,TEM-1,beta-lactamase_2500,P62593,0.508648,NO,205,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.922,-2.938,2.016,,,H,A,0.55,-0.46,0.831,,42.31,PHH,-1.57767,0.361275,0.00255802,0.508648 kka2_1:4_V80N,kka2_1:4_80,Kka2,kka2_1:4,P00552,0.50868,NO,80,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.144,-4.197,3.053,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.168804,0.00488211,0.50868 beta-lactamase_2500_R81V,beta-lactamase_2500_81,TEM-1,beta-lactamase_2500,P62593,0.508725,NO,81,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.466,-3.685,2.219,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.361275,0.00499763,0.508725 kka2_1:2_A78E,kka2_1:2_78,Kka2,kka2_1:2,P00552,0.508752,NO,78,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.744,-3.513,1.769,,0.078,.,B,0.46,-0.53,0.206,,56.06,OHH,-1.863,0.295029,0.00457299,0.508752 beta-lactamase_S264P,beta-lactamase_264,TEM-1,beta-lactamase,P62593,0.508893,NO,264,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.985,-3.022,1.037,4.67475,0.04,,B,0.25,0.29,34.251,34.251,73.78,OPP,-2.19867,0.221079,0.0119399,0.508893 beta-lactamase_L223H,beta-lactamase_223,TEM-1,beta-lactamase,P62593,0.508919,NO,223,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.055,-4.894,3.839,5.42318,0.27,,B,1.3,0.09,1.511,,74.48,HHO,-1.35033,0.221079,0.00372793,0.508919 kka2_1:2_D190R,kka2_1:2_190,Kka2,kka2_1:2,P00552,0.508946,NO,190,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.708,-3.961,3.253,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.295029,0.00247989,0.508946 beta-lactamase_2500_V214F,beta-lactamase_2500_214,TEM-1,beta-lactamase_2500,P62593,0.508977,NO,214,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.299,-3.997,2.698,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.361275,0.00628442,0.508977 beta-lactamase_T261R,beta-lactamase_261,TEM-1,beta-lactamase,P62593,0.509007,NO,261,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.88,-4.126,1.246,5.65483,0.014,E,B,0.53,-0.39,2.449,,77.62,HPP,-1.771,0.221079,0.0123091,0.509007 beta-lactamase_39_I280S,beta-lactamase_39_280,TEM-1,beta-lactamase_39,P62593,0.50903,NO,280,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.0495842,0.0530888,0.50903 kka2_1:8_R38F,kka2_1:8_38,Kka2,kka2_1:8,P00552,0.509116,NO,38,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.207,-4.103,2.896,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.100394,0.00372499,0.509116 kka2_1:8_R38F,kka2_1:8_38,Kka2,kka2_1:8,P00552,0.509116,NO,38,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.207,-4.103,2.896,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.100394,0.00372499,0.509116 beta-lactamase_39_V78R,beta-lactamase_39_78,TEM-1,beta-lactamase_39,P62593,0.50912,NO,78,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.459,-4.181,2.722,,,H,A,0.44,-0.47,1.132,,63.64,HHH,-1.17833,0.0495842,0.00492501,0.50912 kka2_1:1_E161G,kka2_1:1_161,Kka2,kka2_1:1,P00552,0.509161,NO,161,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.581,-3.389,1.808,,0.829,G,A,1.04,2.24,1.612,,92.05,AAB,-1.861,0.520039,0.00760103,0.509161 kka2_1:1_R18G,kka2_1:1_18,Kka2,kka2_1:1,P00552,0.509187,NO,18,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.055,-3.057,1.002,,0.474,T,A,1.2,0.54,11.422,11.422,71.59,ABH,-1.821,0.520039,0.00724065,0.509187 beta-lactamase_156_G240Y,beta-lactamase_156_240,TEM-1,beta-lactamase_156,P62593,0.509239,NO,240,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.111618,0.00591201,0.509239 beta-lactamase_I93S,beta-lactamase_93,TEM-1,beta-lactamase,P62593,0.509252,NO,93,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.401,-3.663,2.262,5.74695,0.128,E,B,0.77,0.44,1.757,,67.83,BHB,-1.873,0.221079,0.00527066,0.509252 kka2_1:2_G151T,kka2_1:2_151,Kka2,kka2_1:2,P00552,0.509253,NO,151,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.873,-3.611,2.738,,0.678,T,l,0.29,1.36,1.357,,49.62,HOH,-1.11433,0.295029,0.00339918,0.509253 E1_Ubiquitin_L43E,E1_Ubiquitin_43,Uba1,E1_Ubiquitin,P0CG63,0.509284,NO,43,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.188,-3.63,2.442,,,E,B,,-1.17,,,,BHH,-1.30733,0.18783,0.00190185,0.509284 E1_Ubiquitin_L43G,E1_Ubiquitin_43,Uba1,E1_Ubiquitin,P0CG63,0.509284,NO,43,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.188,-3.549,2.361,,,E,B,,-1.17,,,,BHH,-1.30733,0.18783,0.00190185,0.509284 kka2_1:8_D159N,kka2_1:8_159,Kka2,kka2_1:8,P00552,0.509306,NO,159,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.82,-3.315,2.495,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.100394,0.0030485,0.509306 kka2_1:8_D159N,kka2_1:8_159,Kka2,kka2_1:8,P00552,0.509306,NO,159,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.82,-3.315,2.495,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.100394,0.0030485,0.509306 kka2_1:2_A64P,kka2_1:2_64,Kka2,kka2_1:2,P00552,0.509354,NO,64,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.496,-4.02,2.524,,0.039,H,A,0.46,-0.57,14.509,14.509,56.06,AHH,-1.334,0.295029,0.00705578,0.509354 beta-lactamase_39_M209E,beta-lactamase_39_209,TEM-1,beta-lactamase_39,P62593,0.50938,NO,209,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.442,-3.84,2.398,,,H,A,0.55,-0.97,1.167,,64.69,HHA,-1.52633,0.0495842,0.00625021,0.50938 kka2_1:1_G164R,kka2_1:1_164,Kka2,kka2_1:1,P00552,0.509597,NO,164,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.869,-3.953,3.084,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.520039,0.00442091,0.509597 beta-lactamase_2500_A182P,beta-lactamase_2500_182,TEM-1,beta-lactamase_2500,P62593,0.509652,NO,182,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.777,-3.952,2.175,,0.136,H,A,0.46,-0.66,2.032,,93.01,OHH,-1.27367,0.361275,0.00559099,0.509652 beta-lactamase_156_G249R,beta-lactamase_156_249,TEM-1,beta-lactamase_156,P62593,0.509675,NO,249,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.111618,0.00220169,0.509675 beta-lactamase_2500_L120A,beta-lactamase_2500_120,TEM-1,beta-lactamase_2500,P62593,0.509697,NO,120,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.044,-3.203,2.159,,,H,A,0.55,-1.13,2.48,,64.69,AHO,-1.13633,0.361275,0.00143563,0.509697 beta-lactamase_2500_D99G,beta-lactamase_2500_99,TEM-1,beta-lactamase_2500,P62593,0.509751,NO,99,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.191,-3.32,2.129,,0.402,G,A,0.75,0.36,1.318,,64.69,PAH,-1.794,0.361275,0.00305446,0.509751 kka2_1:1_L165H,kka2_1:1_165,Kka2,kka2_1:1,P00552,0.509766,NO,165,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-2.453,-4.763,2.31,,0.299,,B,1.59,1.12,2.47,,64.39,OHH,-1.90967,0.520039,0.00801161,0.509766 PSD95pdz3_I338Q,PSD95pdz3_338,PSD95pdz3,PSD95pdz3,P31016,0.509812,NO,338,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.63,-4.031,2.401,5.45113,,,,,13.0087,,,,HHP,-1.55767,0.0758425,0.000862587,0.509812 Pab1_D144P,Pab1_144,Pab1,Pab1,P04147,0.509838,NO,144,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.189,-3.547,2.358,,0.616,H,A,,0.6,,,,HAP,-1.40567,0.175299,0.00121131,0.509838 beta-lactamase_2500_V78A,beta-lactamase_2500_78,TEM-1,beta-lactamase_2500,P62593,0.509841,NO,78,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.459,-3.121,1.662,,,H,A,0.44,-0.47,31.376,31.376,63.64,HHH,-1.17833,0.361275,0.00492501,0.509841 beta-lactamase_625_L197P,beta-lactamase_625_197,TEM-1,beta-lactamase_625,P62593,0.509885,NO,197,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.853,-4.068,3.215,,0.007,S,B,0.55,0.33,1.756,,60.14,HHP,-1.833,0.213352,0.00144602,0.509885 Pab1_S154G,Pab1_154,Pab1,Pab1,P04147,0.50991,NO,154,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.146,-2.725,1.579,,0.208,E,B,0.1,-0.75,,,,HPP,-1.408,0.175299,0.000319331,0.50991 beta-lactamase_2500_C121I,beta-lactamase_2500_121,TEM-1,beta-lactamase_2500,P62593,0.509934,NO,121,C,I,CI,Special,Hydrophobic,5.07,6.02,0.95,198,121,131,10,108.5,166.7,58.2,-0.953,-3.628,2.675,,,H,A,0.46,-0.81,1.174,,63.29,HOP,-1.46767,0.361275,0.000744322,0.509934 beta-lactamase_2500_C75M,beta-lactamase_2500_75,TEM-1,beta-lactamase_2500,P62593,0.510036,NO,75,C,M,CM,Special,Hydrophobic,5.07,5.74,0.67,196,121,149,28,108.5,162.9,54.4,-1.245,-4.597,3.352,,,H,A,0.46,-0.87,0.844,,50,HOO,-1.24333,0.361275,0.0034616,0.510036 kka2_1:4_I196T,kka2_1:4_196,Kka2,kka2_1:4,P00552,0.510048,NO,196,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-2.115,-3.682,1.567,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.168804,0.0107273,0.510048 beta-lactamase_2500_P224A,beta-lactamase_2500_224,TEM-1,beta-lactamase_2500,P62593,0.510152,NO,224,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.893,-3.071,2.178,,0.383,,B,0.52,-0.3,2.666,,74.48,HOH,-1.26433,0.361275,0.00189564,0.510152 beta-lactamase_2500_L284S,beta-lactamase_2500_284,TEM-1,beta-lactamase_2500,P62593,0.510177,NO,284,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.361275,0.0686156,0.510177 beta-lactamase_39_T107K,beta-lactamase_39_107,TEM-1,beta-lactamase_39,P62593,0.510177,NO,107,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.117,-3.447,2.33,,,G,A,0.22,-0.06,2.686,,67.83,HPA,-1.265,0.0495842,0.00239347,0.510177 kka2_1:4_R217G,kka2_1:4_217,Kka2,kka2_1:4,P00552,0.51024,NO,217,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.158,-3.574,2.416,,0.252,T,A,1.2,-0.59,2.074,,52.27,ABH,-1.127,0.168804,0.0047191,0.51024 beta-lactamase_I140K,beta-lactamase_140,TEM-1,beta-lactamase,P62593,0.510249,NO,140,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.733,-3.879,2.146,5.29918,0.128,H,A,1,0.41,1.16,,73.08,PHO,-1.48733,0.221079,0.00597777,0.510249 beta-lactamase_2500_M66A,beta-lactamase_2500_66,TEM-1,beta-lactamase_2500,P62593,0.510293,NO,66,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.362,-3.154,1.792,,0.013,,A,0.55,-0.7,0.502,,73.08,OHH,-1.49567,0.361275,0.00412876,0.510293 beta-lactamase_2500_S266R,beta-lactamase_2500_266,TEM-1,beta-lactamase_2500,P62593,0.510314,NO,266,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.361275,0.0140785,0.510314 beta-lactamase_156_S241L,beta-lactamase_156_241,TEM-1,beta-lactamase_156,P62593,0.510321,NO,241,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.111618,0.00452736,0.510321 kka2_1:2_T125I,kka2_1:2_125,Kka2,kka2_1:2,P00552,0.510334,NO,125,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.622,-3.99,1.368,,0.791,T,A,0.22,0.33,2.029,,92.05,BPH,-1.56933,0.295029,0.00821755,0.510334 beta-lactamase_625_I140H,beta-lactamase_625_140,TEM-1,beta-lactamase_625,P62593,0.510338,NO,140,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.733,-4.991,3.258,,0.128,H,A,0.48,0.41,1.628,,73.08,PHO,-1.48733,0.213352,0.00597777,0.510338 beta-lactamase_2500_I93Q,beta-lactamase_2500_93,TEM-1,beta-lactamase_2500,P62593,0.510445,NO,93,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.401,-4.315,2.914,,0.128,E,B,0.48,0.44,19.374,19.374,67.83,BHB,-1.873,0.361275,0.00527066,0.510445 beta-lactamase_I243Q,beta-lactamase_243,TEM-1,beta-lactamase,P62593,0.510501,NO,243,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.532,-4.079,2.547,5.26886,,E,B,1.68,-1.24,2.289,,50,OHH,-1.46867,0.221079,0.00464034,0.510501 kka2_1:2_R121G,kka2_1:2_121,Kka2,kka2_1:2,P00552,0.510508,NO,121,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.552,-3.527,1.975,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.295029,0.00523326,0.510508 beta-lactamase_2500_A268P,beta-lactamase_2500_268,TEM-1,beta-lactamase_2500,P62593,0.510619,NO,268,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.361275,0.0102525,0.510619 beta-lactamase_2500_D83S,beta-lactamase_2500_83,TEM-1,beta-lactamase_2500,P62593,0.51064,NO,83,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.066,-2.542,1.476,,0.354,H,A,0.75,0.22,0.239,,48.95,HAH,-1.34733,0.361275,0.00205968,0.51064 beta-lactamase_2500_K30E,beta-lactamase_2500_30,TEM-1,beta-lactamase_2500,P62593,0.51073,NO,30,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-2.307,-2.686,0.379,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.361275,0.00448593,0.51073 beta-lactamase_2500_R91D,beta-lactamase_2500_91,TEM-1,beta-lactamase_2500,P62593,0.510746,NO,91,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.392,-3.521,2.129,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.361275,0.00380226,0.510746 beta-lactamase_H110P,beta-lactamase_110,TEM-1,beta-lactamase,P62593,0.510797,NO,110,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-1.706,-2.996,1.29,5.52635,0.341,G,a,0.35,1.08,31.31,31.31,64.69,BBH,-1.73333,0.221079,0.00441499,0.510797 kka2_1:4_L241P,kka2_1:4_241,Kka2,kka2_1:4,P00552,0.510877,NO,241,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.158,-4.275,3.117,,0.08,H,A,0.55,-0.82,1.598,,63.26,HHH,-1.58533,0.168804,0.0117299,0.510877 beta-lactamase_2500_S68I,beta-lactamase_2500_68,TEM-1,beta-lactamase_2500,P62593,0.510926,NO,68,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-0.913,-3.834,2.921,,0.064,G,A,0.27,-1.03,2.824,,64.69,HPP,-1.37233,0.361275,0.000800065,0.510926 beta-lactamase_625_I93W,beta-lactamase_625_93,TEM-1,beta-lactamase_625,P62593,0.510984,NO,93,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.401,-5.418,4.017,,0.128,E,B,0.48,0.44,1.524,,67.83,BHB,-1.873,0.213352,0.00527066,0.510984 kka2_1:1_T146D,kka2_1:1_146,Kka2,kka2_1:1,P00552,0.511018,NO,146,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.978,-3.05,0.072,,0.281,H,A,0.82,0.78,2.105,,92.05,BPB,-1.96833,0.520039,0.00606474,0.511018 beta-lactamase_2500_S104G,beta-lactamase_2500_104,TEM-1,beta-lactamase_2500,P62593,0.511076,NO,104,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.015,-3.017,2.002,,0.04,,b,0.27,0.57,1.133,,63.29,HPO,-1.05267,0.361275,0.00218083,0.511076 beta-lactamase_156_G243H,beta-lactamase_156_243,TEM-1,beta-lactamase_156,P62593,0.511139,NO,243,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.532,,,,,E,B,0.77,-1.24,2.866,,50,BOH,-1.46867,0.111618,0.00464034,0.511139 WW_domain_E178V,WW_domain_178,Yap65,WW_domain,P46937,0.51118,NO,178,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.158,-3.306,2.148,5.22323,,,,,,,,,HAH,-1.299,0.153962,0.0016738,0.51118 kka2_1:2_D208T,kka2_1:2_208,Kka2,kka2_1:2,P00552,0.511194,NO,208,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.708,-3.45,2.742,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.295029,0.00212588,0.511194 kka2_1:1_I207N,kka2_1:1_207,Kka2,kka2_1:1,P00552,0.511206,NO,207,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.175,-4.238,3.063,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.520039,0.00611824,0.511206 beta-lactamase_625_T263N,beta-lactamase_625_263,TEM-1,beta-lactamase_625,P62593,0.511245,NO,263,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.213352,0.0110582,0.511245 kka2_1:8_H162L,kka2_1:8_162,Kka2,kka2_1:8,P00552,0.511278,NO,162,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-2.319,-3.554,1.235,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.100394,0.00616145,0.511278 kka2_1:8_H162L,kka2_1:8_162,Kka2,kka2_1:8,P00552,0.511278,NO,162,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-2.319,-3.554,1.235,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.100394,0.00616145,0.511278 gb1_F256G,gb1_256,gb1,gb1,P06654,0.511384,NO,256,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.241,-3.36,2.119,,,,,,,,,,HHB,-2.04767,0.177985,0.00435993,0.511384 gb1_K254G,gb1_254,gb1,gb1,P06654,0.511384,NO,254,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.748,-3.224,1.476,,,,,,,1.793,,37.28,ABH,-2.195,0.177985,0.00622711,0.511384 gb1_L231W,gb1_231,gb1,gb1,P06654,0.511384,NO,231,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.603,-4.36,2.757,,,,,,,0.219,,11.83,BHH,-1.82633,0.177985,0.00322797,0.511384 gb1_Y271K,gb1_271,gb1,gb1,P06654,0.511384,NO,271,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-1.181,-3.459,2.278,,,,,,,,,,PHA,-1.92933,0.177985,0.00236544,0.511384 gb1_Y271R,gb1_271,gb1,gb1,P06654,0.511384,NO,271,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-1.181,-3.71,2.529,,,,,,,,,,PHA,-1.92933,0.177985,0.00236544,0.511384 kka2_1:4_R258C,kka2_1:4_258,Kka2,kka2_1:4,P00552,0.511418,NO,258,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.626,-2.089,0.463,,0.316,H,A,1.2,-0.85,2.655,,53.03,HBH,-1.25933,0.168804,0.00983174,0.511418 beta-lactamase_2500_G52H,beta-lactamase_2500_52,TEM-1,beta-lactamase_2500,P62593,0.511465,NO,52,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.149,-4.712,3.563,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.361275,0.00340138,0.511465 kka2_1:8_D159P,kka2_1:8_159,Kka2,kka2_1:8,P00552,0.511521,NO,159,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.82,-3.747,2.927,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.100394,0.0030485,0.511521 kka2_1:8_D159P,kka2_1:8_159,Kka2,kka2_1:8,P00552,0.511521,NO,159,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.82,-3.747,2.927,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.100394,0.0030485,0.511521 kka2_1:2_F240L,kka2_1:2_240,Kka2,kka2_1:2,P00552,0.511531,NO,240,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-0.911,-2.161,1.25,,,H,A,0.58,-1.21,0.373,,50.38,BHH,-1.67267,0.295029,0.00552543,0.511531 kka2_1:1_G201S,kka2_1:1_201,Kka2,kka2_1:1,P00552,0.511694,NO,201,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.56,-2.438,0.878,,0.149,T,l,0.29,-0.57,16.092,16.092,52.65,POB,-1.92233,0.520039,0.00820117,0.511694 beta-lactamase_2500_L218D,beta-lactamase_2500_218,TEM-1,beta-lactamase_2500,P62593,0.511719,NO,218,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.391,-3.905,2.514,,,I,b,0.55,-0.53,9.151,9.151,74.48,OHH,-1.58867,0.361275,0.00618274,0.511719 kka2_1:2_D220R,kka2_1:2_220,Kka2,kka2_1:2,P00552,0.511761,NO,220,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.787,-4.005,3.218,,,H,A,0.75,-1.14,0.745,,46.59,PAH,-1.152,0.295029,0.00158066,0.511761 beta-lactamase_2500_L223S,beta-lactamase_2500_223,TEM-1,beta-lactamase_2500,P62593,0.511972,NO,223,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.055,-3.587,2.532,,0.27,,B,0.55,0.09,1.334,,74.48,HHO,-1.35033,0.361275,0.00372793,0.511972 beta-lactamase_G226I,beta-lactamase_226,TEM-1,beta-lactamase,P62593,0.512067,NO,226,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.461,-4.177,2.716,5.70682,0.701,T,l,0.77,-0.25,3.199,,74.48,HOH,-1.42933,0.221079,0.00665294,0.512067 beta-lactamase_A123L,beta-lactamase_123,TEM-1,beta-lactamase,P62593,0.51216,NO,123,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.834,-3.096,2.262,4.70061,0.039,H,A,0.52,-0.72,0.705,,41.26,PHH,-1.47367,0.221079,0.0010157,0.51216 beta-lactamase_625_T139P,beta-lactamase_625_139,TEM-1,beta-lactamase_625,P62593,0.512161,NO,139,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.901,-3.919,2.018,,0.216,H,A,0.22,0.39,2.256,,77.62,PPH,-2.04667,0.213352,0.00441837,0.512161 beta-lactamase_I125H,beta-lactamase_125,TEM-1,beta-lactamase,P62593,0.512208,NO,125,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.441,-4.965,3.524,5.23481,,H,A,2.82,-0.7,2.301,,63.29,HHP,-1.248,0.221079,0.00383964,0.512208 kka2_1:1_D250V,kka2_1:1_250,Kka2,kka2_1:1,P00552,0.512208,NO,250,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.015,-3.813,2.798,,0.274,.,b,0.75,-0.46,4.177,,51.89,OAP,-1.83933,0.520039,0.0177103,0.512208 kka2_1:2_D216K,kka2_1:2_216,Kka2,kka2_1:2,P00552,0.512273,NO,216,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.785,-3.508,2.723,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.295029,0.00229969,0.512273 beta-lactamase_2500_A77W,beta-lactamase_2500_77,TEM-1,beta-lactamase_2500,P62593,0.512286,NO,77,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.234,-5.367,4.133,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.361275,0.00282362,0.512286 kka2_1:2_T51D,kka2_1:2_51,Kka2,kka2_1:2,P00552,0.512309,NO,51,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.199,-3.85,1.651,,0.05,E,B,0.22,-0.05,13.165,13.165,63.64,BPA,-1.76767,0.295029,0.00628861,0.512309 beta-lactamase_2500_E87N,beta-lactamase_2500_87,TEM-1,beta-lactamase_2500,P62593,0.51242,NO,87,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.421,-3.684,2.263,,0.048,,B,1.04,0.92,17.923,17.923,64.69,PAP,-1.969,0.361275,0.00337888,0.51242 beta-lactamase_0_V42Q,beta-lactamase_0_42,TEM-1,beta-lactamase_0,P62593,0.512433,NO,42,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.564,-4.229,2.665,,0.017,E,B,0.44,-0.51,1.659,,63.99,BHO,-1.042,0.0500837,0.00404515,0.512433 kka2_1:4_D82Y,kka2_1:4_82,Kka2,kka2_1:4,P00552,0.512482,NO,82,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.946,-4.406,2.46,,0.341,E,b,0.75,0.52,11.923,11.923,63.64,HAH,-1.98,0.168804,0.00637516,0.512482 beta-lactamase_D177G,beta-lactamase_177,TEM-1,beta-lactamase,P62593,0.512554,NO,177,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.967,-2.392,1.425,5.08038,0.006,T,L,1.59,-1.02,3.536,,64.69,BAP,-0.873667,0.221079,0.000864022,0.512554 kka2_1:2_I254K,kka2_1:2_254,Kka2,kka2_1:2,P00552,0.512599,NO,254,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.933,-3.795,1.862,,0.135,H,A,1.52,-0.6,2.562,,71.59,BHH,-1.668,0.295029,0.0132375,0.512599 beta-lactamase_2500_Y95C,beta-lactamase_2500_95,TEM-1,beta-lactamase_2500,P62593,0.512668,NO,95,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-1.715,-4.95,3.235,,0.122,,b,0.21,-0.37,2.914,,77.62,BHP,-2.16167,0.361275,0.00479449,0.512668 beta-lactamase_0_M115R,beta-lactamase_0_115,TEM-1,beta-lactamase_0,P62593,0.512669,NO,115,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.389,-2.862,1.473,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.0500837,0.0034337,0.512669 beta-lactamase_L137H,beta-lactamase_137,TEM-1,beta-lactamase,P62593,0.512724,NO,137,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.03,-4.934,3.904,5.20117,,H,A,1.07,-0.38,0.674,,42.31,HHP,-1.58933,0.221079,0.00278599,0.512724 kka2_1:2_I196W,kka2_1:2_196,Kka2,kka2_1:2,P00552,0.512746,NO,196,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-2.115,-4.933,2.818,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.295029,0.0107273,0.512746 kka2_1:2_L103P,kka2_1:2_103,Kka2,kka2_1:2,P00552,0.512757,NO,103,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-2.362,-3.937,1.575,,0.394,T,A,0.55,-0.99,3.499,,63.64,HHP,-1.534,0.295029,0.00574792,0.512757 kka2_1:8_Y257M,kka2_1:8_257,Kka2,kka2_1:8,P00552,0.512803,NO,257,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-1.064,-4.488,3.424,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.100394,0.0148191,0.512803 kka2_1:8_Y257M,kka2_1:8_257,Kka2,kka2_1:8,P00552,0.512803,NO,257,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-1.064,-4.488,3.424,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.100394,0.0148191,0.512803 kka2_1:2_G99R,kka2_1:2_99,Kka2,kka2_1:2,P00552,0.51281,NO,99,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.596,-3.961,3.365,,0.368,S,g,0.29,-0.87,,,,OOP,-1.63067,0.295029,0.00186055,0.51281 kka2_1:2_P109R,kka2_1:2_109,Kka2,kka2_1:2,P00552,0.51294,NO,109,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.412,-3.997,2.585,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.295029,0.0070929,0.51294 kka2_1:8_G213A,kka2_1:8_213,Kka2,kka2_1:8,P00552,0.512948,NO,213,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.596,-2.881,2.285,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.100394,0.00187654,0.512948 kka2_1:8_G213A,kka2_1:8_213,Kka2,kka2_1:8,P00552,0.512948,NO,213,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.596,-2.881,2.285,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.100394,0.00187654,0.512948 beta-lactamase_L47R,beta-lactamase_47,TEM-1,beta-lactamase,P62593,0.512999,NO,47,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.876,-2.668,0.792,5.27297,0.007,E,B,1.07,0.2,1.244,,67.83,AHA,-1.639,0.221079,0.00439844,0.512999 beta-lactamase_2500_V72K,beta-lactamase_2500_72,TEM-1,beta-lactamase_2500,P62593,0.51301,NO,72,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.658,-3.754,2.096,,,H,A,0.44,-1.03,2.079,,65.73,BHH,-1.32167,0.361275,0.00501194,0.51301 kka2_1:2_A119K,kka2_1:2_119,Kka2,kka2_1:2,P00552,0.513033,NO,119,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.073,-3.574,2.501,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.295029,0.00441074,0.513033 beta-lactamase_156_T131I,beta-lactamase_156_131,TEM-1,beta-lactamase_156,P62593,0.51305,NO,131,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.328,-3.758,2.43,,,H,A,0.22,-0.69,2.031,,67.48,PPH,-1.00867,0.111618,0.00345886,0.51305 kka2_1:2_L158Q,kka2_1:2_158,Kka2,kka2_1:2,P00552,0.51309,NO,158,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.947,-4.338,2.391,,0.095,,B,1.59,0.77,7.588,,63.64,AHA,-1.25333,0.295029,0.00529068,0.51309 kka2_1:2_L126E,kka2_1:2_126,Kka2,kka2_1:2,P00552,0.513103,NO,126,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.246,-3.857,2.611,,0.285,S,B,0.55,0.12,1.392,,51.89,PHA,-1.744,0.295029,0.0066485,0.513103 WW_domain_T196P,WW_domain_196,Yap65,WW_domain,P46937,0.513114,NO,196,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.782,-3.786,2.004,5.5744,,,,,,5.836,,70.04,PPP,-1.732,0.153962,0.00421377,0.513114 beta-lactamase_2500_G52M,beta-lactamase_2500_52,TEM-1,beta-lactamase_2500,P62593,0.513121,NO,52,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.149,-4.888,3.739,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.361275,0.00340138,0.513121 beta-lactamase_2500_G226W,beta-lactamase_2500_226,TEM-1,beta-lactamase_2500,P62593,0.513126,NO,226,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.461,-5.464,4.003,,0.701,T,l,0.29,-0.25,5.086,,74.48,HOH,-1.42933,0.361275,0.00665294,0.513126 kka2_1:2_V36R,kka2_1:2_36,Kka2,kka2_1:2,P00552,0.513288,NO,36,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-0.898,-4.231,3.333,,0.292,E,B,1.48,0.21,1.064,,52.27,HHH,-1.484,0.295029,0.00245633,0.513288 kka2_1:8_G245P,kka2_1:8_245,Kka2,kka2_1:8,P00552,0.51331,NO,245,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.812,-3.931,3.119,,0.655,T,g,0.75,0.03,1.148,,65.53,HOH,-1.19833,0.100394,0.00683899,0.51331 kka2_1:8_G245P,kka2_1:8_245,Kka2,kka2_1:8,P00552,0.51331,NO,245,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.812,-3.931,3.119,,0.655,T,g,0.75,0.03,1.148,,65.53,HOH,-1.19833,0.100394,0.00683899,0.51331 beta-lactamase_39_E35P,beta-lactamase_39_35,TEM-1,beta-lactamase_39,P62593,0.513411,NO,35,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-0.869,-3.68,2.811,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.0495842,0.00174441,0.513411 beta-lactamase_625_E35N,beta-lactamase_625_35,TEM-1,beta-lactamase_625,P62593,0.513451,NO,35,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-0.869,-3.445,2.576,,0.15,H,A,1.04,0.21,0.664,,46.85,HAA,-1.88667,0.213352,0.00174441,0.513451 beta-lactamase_156_G142P,beta-lactamase_156_142,TEM-1,beta-lactamase_156,P62593,0.513548,NO,142,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.707,-3.877,3.17,,0.034,,p,0.29,-0.64,0.325,,64.69,OOO,-0.834,0.111618,0.00060149,0.513548 beta-lactamase_T69V,beta-lactamase_69,TEM-1,beta-lactamase,P62593,0.51361,NO,69,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-0.973,-3.175,2.202,5.16042,,G,A,0.69,-1.24,0.505,,93.01,PPH,-1.01833,0.221079,0.00127498,0.51361 kka2_1:8_D220N,kka2_1:8_220,Kka2,kka2_1:8,P00552,0.513671,NO,220,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.787,-3.336,2.549,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.100394,0.00158066,0.513671 kka2_1:8_D220N,kka2_1:8_220,Kka2,kka2_1:8,P00552,0.513671,NO,220,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.787,-3.336,2.549,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.100394,0.00158066,0.513671 beta-lactamase_625_D231P,beta-lactamase_625_231,TEM-1,beta-lactamase_625,P62593,0.513719,NO,231,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.816,-3.68,2.864,,,E,B,0.75,-1.06,1.025,,65.38,HAB,-0.994,0.213352,0.00107395,0.513719 kka2_1:2_R202D,kka2_1:2_202,Kka2,kka2_1:2,P00552,0.513744,NO,202,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.761,-2.83,1.069,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.295029,0.00696498,0.513744 beta-lactamase_2500_T198P,beta-lactamase_2500_198,TEM-1,beta-lactamase_2500,P62593,0.513757,NO,198,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.168,-2.894,0.726,,0.489,,B,0.22,-0.13,0.37,,73.78,HPH,-1.98767,0.361275,0.004311,0.513757 beta-lactamase_625_R91I,beta-lactamase_625_91,TEM-1,beta-lactamase_625,P62593,0.513793,NO,91,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.392,-4.049,2.657,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.213352,0.00380226,0.513793 kka2_1:4_L94Y,kka2_1:4_94,Kka2,kka2_1:4,P00552,0.513816,NO,94,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.618,-4.101,2.483,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.168804,0.00520888,0.513816 Pab1_F149R,Pab1_149,Pab1,Pab1,P04147,0.51385,NO,149,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.149,-3.975,2.826,,0.183,T,A,1.33,1.09,,,,HHO,-1.27767,0.175299,0.000325688,0.51385 kka2_1:1_T28I,kka2_1:1_28,Kka2,kka2_1:1,P00552,0.513854,NO,28,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.883,-3.847,1.964,,0.353,S,B,0.22,2.02,1.12,,63.64,PPH,-1.74467,0.520039,0.00743084,0.513854 beta-lactamase_2500_P25A,beta-lactamase_2500_25,TEM-1,beta-lactamase_2500,P62593,0.513866,NO,25,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.526,-2.222,0.696,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.361275,0.00347571,0.513866 beta-lactamase_2500_A215R,beta-lactamase_2500_215,TEM-1,beta-lactamase_2500,P62593,0.513911,NO,215,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.503,-3.862,2.359,,,,a,0.46,-0.93,3.516,,74.48,HHO,-1.42633,0.361275,0.00544007,0.513911 kka2_1:1_Q4I,kka2_1:1_4,Kka2,kka2_1:1,P00552,0.513981,NO,4,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.361,-3.887,1.526,,,,,,,5.615,,71.59,APA,-1.95533,0.520039,0.00239179,0.513981 beta-lactamase_39_L135D,beta-lactamase_39_135,TEM-1,beta-lactamase_39,P62593,0.514015,NO,135,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.002,-4.125,3.123,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.0495842,0.00244423,0.514015 beta-lactamase_2500_L197F,beta-lactamase_2500_197,TEM-1,beta-lactamase_2500,P62593,0.514072,NO,197,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.853,-3.685,2.832,,0.007,S,B,0.55,0.33,2.421,,60.14,HHP,-1.833,0.361275,0.00144602,0.514072 beta-lactamase_625_G142K,beta-lactamase_625_142,TEM-1,beta-lactamase_625,P62593,0.5141,NO,142,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.707,-3.645,2.938,,0.034,,p,0.29,-0.64,1.35,,64.69,OOO,-0.834,0.213352,0.00060149,0.5141 kka2_1:4_D101G,kka2_1:4_101,Kka2,kka2_1:4,P00552,0.514114,NO,101,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.028,-3.238,2.21,,0.213,E,B,0.75,-1.24,8.707,,63.64,PAH,-1.534,0.168804,0.00423361,0.514114 kka2_1:1_E199R,kka2_1:1_199,Kka2,kka2_1:1,P00552,0.514153,NO,199,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.234,-3.022,0.788,,0.508,E,B,1.04,-0.43,3.012,,65.53,HAP,-2.133,0.520039,0.00854122,0.514153 beta-lactamase_2500_A235I,beta-lactamase_2500_235,TEM-1,beta-lactamase_2500,P62593,0.514181,NO,235,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.266,-3.683,2.417,,0.32,E,B,0.46,-0.86,0.891,,50,OHO,-0.89,0.361275,0.00493474,0.514181 kka2_1:2_V153Q,kka2_1:2_153,Kka2,kka2_1:2,P00552,0.514191,NO,153,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.092,-4.272,3.18,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.295029,0.00501119,0.514191 kka2_1:4_A78Q,kka2_1:4_78,Kka2,kka2_1:4,P00552,0.514199,NO,78,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.744,-3.972,2.228,,0.078,.,B,0.46,-0.53,0.594,,56.06,OHH,-1.863,0.168804,0.00457299,0.514199 kka2_1:8_A144K,kka2_1:8_144,Kka2,kka2_1:8,P00552,0.514338,NO,144,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.859,-3.568,2.709,,,H,A,1.04,0.21,1.118,,52.65,BHB,-1.72933,0.100394,0.00231095,0.514338 kka2_1:8_A144K,kka2_1:8_144,Kka2,kka2_1:8,P00552,0.514338,NO,144,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.859,-3.568,2.709,,,H,A,1.04,0.21,1.118,,52.65,BHB,-1.72933,0.100394,0.00231095,0.514338 beta-lactamase_625_T116F,beta-lactamase_625_116,TEM-1,beta-lactamase_625,P62593,0.514355,NO,116,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.28,-4.243,2.963,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.213352,0.00336175,0.514355 beta-lactamase_156_R162V,beta-lactamase_156_162,TEM-1,beta-lactamase_156,P62593,0.514412,NO,162,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.016,-3.642,2.626,,0.124,S,B,1.2,-0.37,7.444,,64.69,ABH,-1.25,0.111618,0.000561334,0.514412 kka2_1:1_H8K,kka2_1:1_8,Kka2,kka2_1:1,P00552,0.514547,NO,8,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-2.759,-3.463,0.704,,,,,,,16.971,16.971,71.59,HBH,-2.25467,0.520039,0.00256422,0.514547 kka2_1:2_E3V,kka2_1:2_3,Kka2,kka2_1:2,P00552,0.514585,NO,3,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.199,-3.503,1.304,,,,,,,7.22,,92.05,HAP,-2.11567,0.295029,0.00267607,0.514585 PSD95pdz3_I388P,PSD95pdz3_388,PSD95pdz3,PSD95pdz3,P31016,0.51461,NO,388,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.63,-3.786,2.156,5.17282,,,,,16.0025,,,,PHH,-1.54967,0.0758425,0.000151216,0.51461 kka2_1:4_W15K,kka2_1:4_15,Kka2,kka2_1:4,P00552,0.514614,NO,15,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-1.392,-3.944,2.552,,0.01,G,A,0.47,0.15,0.943,,52.27,HHH,-2.10533,0.168804,0.00585505,0.514614 beta-lactamase_L73E,beta-lactamase_73,TEM-1,beta-lactamase,P62593,0.514627,NO,73,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.507,-3.924,2.417,5.84139,,H,A,1.75,-0.64,2.09,,67.83,HHH,-1.487,0.221079,0.00488983,0.514627 kka2_1:1_R211G,kka2_1:1_211,Kka2,kka2_1:1,P00552,0.51464,NO,211,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-0.899,-3.41,2.511,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.520039,0.00204888,0.51464 beta-lactamase_2500_E119M,beta-lactamase_2500_119,TEM-1,beta-lactamase_2500,P62593,0.514657,NO,119,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.412,-4.79,3.378,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.361275,0.00386966,0.514657 kka2_1:1_Q4F,kka2_1:1_4,Kka2,kka2_1:1,P00552,0.514671,NO,4,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.361,-4.126,1.765,,,,,,,5.615,,71.59,APA,-1.95533,0.520039,0.00239179,0.514671 beta-lactamase_625_E272P,beta-lactamase_625_272,TEM-1,beta-lactamase_625,P62593,0.514685,NO,272,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.213352,0.00545371,0.514685 beta-lactamase_625_D212H,beta-lactamase_625_212,TEM-1,beta-lactamase_625,P62593,0.514694,NO,212,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.624,-4.56,2.936,,0.037,,b,0.75,-0.58,1.516,,74.48,HAB,-1.77667,0.213352,0.00644302,0.514694 beta-lactamase_2500_N274G,beta-lactamase_2500_274,TEM-1,beta-lactamase_2500,P62593,0.514696,NO,274,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.361275,0.0110418,0.514696 kka2_1:1_S40C,kka2_1:1_40,Kka2,kka2_1:1,P00552,0.514701,NO,40,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.645,-3.648,1.003,,0.32,E,B,0.27,-0.9,25.997,25.997,71.59,HPH,-1.91567,0.520039,0.00693477,0.514701 gb1_N261S,gb1_261,gb1,gb1,P06654,0.514702,NO,261,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-1.863,-1.825,-0.038,,,,,,,1.191,,44.87,HPA,-2.16033,0.177985,0.0061875,0.514702 beta-lactamase_625_D231Y,beta-lactamase_625_231,TEM-1,beta-lactamase_625,P62593,0.514731,NO,231,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.816,-4.385,3.569,,,E,B,0.75,-1.06,1.025,,65.38,HAB,-0.994,0.213352,0.00107395,0.514731 beta-lactamase_R241I,beta-lactamase_241,TEM-1,beta-lactamase,P62593,0.514766,NO,241,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.433,-3.892,2.459,5.02621,0.094,E,B,0.68,-0.16,1.327,,50,PBO,-1.42967,0.221079,0.00452736,0.514766 kka2_1:2_H135M,kka2_1:2_135,Kka2,kka2_1:2,P00552,0.514789,NO,135,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-1.331,-4.614,3.283,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.295029,0.00532566,0.514789 beta-lactamase_I256Y,beta-lactamase_256,TEM-1,beta-lactamase,P62593,0.5148,NO,256,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.621,-4.029,2.408,5.3196,,E,B,1,-0.84,1.615,,73.08,BHH,-1.80667,0.221079,0.00710634,0.5148 beta-lactamase_0_M180F,beta-lactamase_0_180,TEM-1,beta-lactamase_0,P62593,0.514832,NO,180,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-2.795,-3.981,1.186,,0.242,,B,0.55,-0.94,2.892,,77.62,PHO,-1.56433,0.0500837,0.00552048,0.514832 beta-lactamase_L100G,beta-lactamase_100,TEM-1,beta-lactamase,P62593,0.514839,NO,100,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.218,-3.854,2.636,5.60291,0.343,,B,1.3,0.13,1.173,,63.29,AHH,-1.23467,0.221079,0.00413885,0.514839 beta-lactamase_V78H,beta-lactamase_78,TEM-1,beta-lactamase,P62593,0.514839,NO,78,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.459,-5.015,3.556,4.79197,,H,A,0.96,-0.47,1.132,,63.64,HHH,-1.17833,0.221079,0.00492501,0.514839 kka2_1:4_D159L,kka2_1:4_159,Kka2,kka2_1:4,P00552,0.514863,NO,159,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.82,-3.871,3.051,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.168804,0.0030485,0.514863 beta-lactamase_W208Q,beta-lactamase_208,TEM-1,beta-lactamase,P62593,0.514881,NO,208,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-0.818,-4.124,3.306,5.26277,0.067,H,A,0.99,-0.65,,,,AHH,-1.44133,0.221079,0.00126609,0.514881 beta-lactamase_G52I,beta-lactamase_52,TEM-1,beta-lactamase,P62593,0.514951,NO,52,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.149,-4.163,3.014,5.12093,0.299,,l,0.77,-0.04,2.103,,64.69,POB,-1.66267,0.221079,0.00340138,0.514951 beta-lactamase_625_V214E,beta-lactamase_625_214,TEM-1,beta-lactamase_625,P62593,0.514968,NO,214,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.299,-3.704,2.405,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.213352,0.00628442,0.514968 beta-lactamase_39_L167R,beta-lactamase_39_167,TEM-1,beta-lactamase_39,P62593,0.514971,NO,167,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.138,-2.876,1.738,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.0495842,0.00303566,0.514971 beta-lactamase_R162Y,beta-lactamase_162,TEM-1,beta-lactamase,P62593,0.514971,NO,162,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.016,-4.207,3.191,5.34456,0.124,S,B,0.68,-0.37,31.656,31.656,64.69,ABH,-1.25,0.221079,0.000561334,0.514971 kka2_1:2_R38P,kka2_1:2_38,Kka2,kka2_1:2,P00552,0.515105,NO,38,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.207,-4.041,2.834,,0.355,E,B,1.2,-1.13,6.872,6.872,52.27,HBH,-1.28567,0.295029,0.00372499,0.515105 kka2_1:8_V113R,kka2_1:8_113,Kka2,kka2_1:8,P00552,0.515113,NO,113,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.233,-4.233,3,,0.008,H,A,1.48,-1.17,1.254,,52.27,BHP,-2.08367,0.100394,0.00650191,0.515113 kka2_1:8_V113R,kka2_1:8_113,Kka2,kka2_1:8,P00552,0.515113,NO,113,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.233,-4.233,3,,0.008,H,A,1.48,-1.17,1.254,,52.27,BHP,-2.08367,0.100394,0.00650191,0.515113 kka2_1:1_R202C,kka2_1:1_202,Kka2,kka2_1:1,P00552,0.515123,NO,202,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.761,-3.597,1.836,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.520039,0.00696498,0.515123 beta-lactamase_2500_A170E,beta-lactamase_2500_170,TEM-1,beta-lactamase_2500,P62593,0.515126,NO,170,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.237,-3.626,2.389,,0.126,,L,0.46,-0.35,2.427,,64.69,AHH,-1.63267,0.361275,0.00431903,0.515126 Pab1_G188I,Pab1_188,Pab1,Pab1,P04147,0.515166,NO,188,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.809,-4.052,3.243,,0.379,E,g,,2.18,,,,POH,-1.14633,0.175299,0.000280911,0.515166 kka2_1:2_I228S,kka2_1:2_228,Kka2,kka2_1:2,P00552,0.515239,NO,228,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.142,-3.711,2.569,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.295029,0.00458834,0.515239 kka2_1:8_K112D,kka2_1:8_112,Kka2,kka2_1:8,P00552,0.515257,NO,112,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-2.491,-3.95,1.459,,0.076,H,A,1.3,-1.37,10.58,10.58,56.06,ABH,-2.00133,0.100394,0.00645389,0.515257 kka2_1:8_K112D,kka2_1:8_112,Kka2,kka2_1:8,P00552,0.515257,NO,112,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-2.491,-3.95,1.459,,0.076,H,A,1.3,-1.37,10.58,10.58,56.06,ABH,-2.00133,0.100394,0.00645389,0.515257 kka2_1:8_A224N,kka2_1:8_224,Kka2,kka2_1:8,P00552,0.515314,NO,224,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.977,-3.898,2.921,,,H,A,0.46,-1.26,0.357,,63.64,HHP,-1.41033,0.100394,0.00352047,0.515314 kka2_1:8_A224N,kka2_1:8_224,Kka2,kka2_1:8,P00552,0.515314,NO,224,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.977,-3.898,2.921,,,H,A,0.46,-1.26,0.357,,63.64,HHP,-1.41033,0.100394,0.00352047,0.515314 beta-lactamase_2500_F58K,beta-lactamase_2500_58,TEM-1,beta-lactamase_2500,P62593,0.515386,NO,58,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-2.914,-3.623,0.709,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.361275,0.00523369,0.515386 beta-lactamase_S240F,beta-lactamase_240,TEM-1,beta-lactamase,P62593,0.515399,NO,240,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.537,-4.217,2.68,4.75024,,,B,0.74,-0.74,0.357,,65.38,OPB,-1.263,0.221079,0.00591201,0.515399 Pab1_I183P,Pab1_183,Pab1,Pab1,P04147,0.515437,NO,183,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.302,-3.915,2.613,,0.308,T,B,1,1.08,1.29,,75.56,HHA,-1.27167,0.175299,0.000574345,0.515437 Pab1_H172Y,Pab1_172,Pab1,Pab1,P04147,0.515465,NO,172,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-1.21,-3.08,1.87,,0.076,E,B,0.35,-0.87,,,,HBH,-1.26667,0.175299,0.000296642,0.515465 beta-lactamase_2500_T138P,beta-lactamase_2500_138,TEM-1,beta-lactamase_2500,P62593,0.51547,NO,138,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.506,-3.038,0.532,,0.662,H,A,0.22,-0.03,30.445,30.445,73.78,HPP,-1.81233,0.361275,0.00487868,0.51547 kka2_1:8_L102D,kka2_1:8_102,Kka2,kka2_1:8,P00552,0.515473,NO,102,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.804,-4.17,3.366,,,T,A,1.59,-1.17,0.97,,42.42,AHH,-1.398,0.100394,0.00201332,0.515473 kka2_1:8_L102D,kka2_1:8_102,Kka2,kka2_1:8,P00552,0.515473,NO,102,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.804,-4.17,3.366,,,T,A,1.59,-1.17,0.97,,42.42,AHH,-1.398,0.100394,0.00201332,0.515473 beta-lactamase_156_S241R,beta-lactamase_156_241,TEM-1,beta-lactamase_156,P62593,0.515517,NO,241,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.433,-3.314,1.881,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.111618,0.00452736,0.515517 beta-lactamase_T27E,beta-lactamase_27,TEM-1,beta-lactamase,P62593,0.515537,NO,27,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.905,-2.714,0.809,5.39752,0.007,H,A,0.69,-0.37,0.745,,93.01,APH,-1.97933,0.221079,0.00306559,0.515537 beta-lactamase_0_I171Y,beta-lactamase_0_171,TEM-1,beta-lactamase_0,P62593,0.515601,NO,171,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-2.431,-4.204,1.773,,0.361,,B,0.48,0.53,16.954,16.954,77.62,HHO,-1.55533,0.0500837,0.00623355,0.515601 kka2_1:1_H139Y,kka2_1:1_139,Kka2,kka2_1:1,P00552,0.515635,NO,139,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-2.809,-3.482,0.673,,0.471,H,A,0.17,0.68,1.153,,63.64,BBB,-2.22,0.520039,0.00734779,0.515635 kka2_1:1_L19P,kka2_1:1_19,Kka2,kka2_1:1,P00552,0.515658,NO,19,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.254,-4.281,3.027,,0.08,T,A,0.55,-0.26,17.165,17.165,65.53,BHH,-2.221,0.520039,0.00620703,0.515658 beta-lactamase_156_A185L,beta-lactamase_156_185,TEM-1,beta-lactamase_156,P62593,0.515791,NO,185,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.406,-2.064,0.658,,,H,A,0.46,-1.02,0.365,,65.03,HHP,-1.84033,0.111618,0.00467449,0.515791 beta-lactamase_625_T107N,beta-lactamase_625_107,TEM-1,beta-lactamase_625,P62593,0.515798,NO,107,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.117,-3.473,2.356,,,G,A,0.22,-0.06,3.676,,67.83,HPA,-1.265,0.213352,0.00239347,0.515798 beta-lactamase_39_S104L,beta-lactamase_39_104,TEM-1,beta-lactamase_39,P62593,0.515842,NO,104,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.015,-3.359,2.344,,0.04,,b,0.27,0.57,4.02,,63.29,HPO,-1.05267,0.0495842,0.00218083,0.515842 kka2_1:1_G95K,kka2_1:1_95,Kka2,kka2_1:1,P00552,0.515867,NO,95,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-2.403,-3.514,1.111,,0.126,E,B,0.29,-0.74,7.822,,71.59,HOA,-2.198,0.520039,0.00743616,0.515867 kka2_1:1_F171S,kka2_1:1_171,Kka2,kka2_1:1,P00552,0.515874,NO,171,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.326,-3.759,2.433,,0.154,H,A,1.62,-0.1,13.679,13.679,63.64,HHH,-1.45433,0.520039,0.00821426,0.515874 beta-lactamase_2500_Y103I,beta-lactamase_2500_103,TEM-1,beta-lactamase_2500,P62593,0.515901,NO,103,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-1.33,-3.874,2.544,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.361275,0.00443048,0.515901 beta-lactamase_39_L248P,beta-lactamase_39_248,TEM-1,beta-lactamase_39,P62593,0.515989,NO,248,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.0495842,0.00428493,0.515989 beta-lactamase_625_F228E,beta-lactamase_625_228,TEM-1,beta-lactamase_625,P62593,0.516049,NO,228,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-2.342,-3.551,1.209,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.213352,0.0046669,0.516049 Ubiquitin_D58F,Ubiquitin_58,Uba1,Ubiquitin,P0CG48,0.516129,NO,58,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.622,-4.013,2.391,5.06391,0.457,G,A,,-0.54,,,,PAH,-1.60267,0.205827,0.000639847,0.516129 Ubiquitin_E34R,Ubiquitin_34,Uba1,Ubiquitin,P0CG48,0.516129,NO,34,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.294,-3.574,2.28,5.02178,0.406,H,A,1.62,0.6,1.295,,35.62,BAO,-1.24933,0.205827,0.000686048,0.516129 Ubiquitin_L8F,Ubiquitin_8,Uba1,Ubiquitin,P0CG48,0.516129,NO,8,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.723,-2.989,1.266,5.28016,0.664,T,A,0.08,-0.34,0.664,,29.05,PHP,-1.51567,0.205827,0.000726165,0.516129 Ubiquitin_Q41D,Ubiquitin_41,Uba1,Ubiquitin,P0CG48,0.516129,NO,41,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-1.329,-3.446,2.117,4.9201,0.017,E,B,0.12,-0.98,0.812,,30.07,PPB,-1.55067,0.205827,0.000521668,0.516129 kka2_1:1_D134G,kka2_1:1_134,Kka2,kka2_1:1,P00552,0.516227,NO,134,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.969,-3.259,2.29,,0.421,B,B,0.75,0.31,2.329,,49.62,HAB,-1.057,0.520039,0.00270812,0.516227 kka2_1:2_E262K,kka2_1:2_262,Kka2,kka2_1:2,P00552,0.516228,NO,262,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-0.829,-3.058,2.229,,0.059,G,A,1.04,-0.18,2.383,,42.42,AAH,-0.816,0.295029,0.0191586,0.516228 beta-lactamase_2500_T139W,beta-lactamase_2500_139,TEM-1,beta-lactamase_2500,P62593,0.516296,NO,139,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.901,-5.432,3.531,,0.216,H,A,0.22,0.39,2.256,,77.62,PPH,-2.04667,0.361275,0.00441837,0.516296 beta-lactamase_T261N,beta-lactamase_261,TEM-1,beta-lactamase,P62593,0.516313,NO,261,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.88,-4.145,1.265,5.65483,0.014,E,B,0.53,-0.39,2.449,,77.62,HPP,-1.771,0.221079,0.0123091,0.516313 kka2_1:2_A108F,kka2_1:2_108,Kka2,kka2_1:2,P00552,0.516325,NO,108,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.061,-4.427,2.366,,0.243,.,B,0.46,-1.34,2.462,,71.59,HHO,-1.57033,0.295029,0.00751209,0.516325 beta-lactamase_625_S283P,beta-lactamase_625_283,TEM-1,beta-lactamase_625,P62593,0.516336,NO,283,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.213352,0.0429138,0.516336 kka2_1:2_C131G,kka2_1:2_131,Kka2,kka2_1:2,P00552,0.516381,NO,131,C,G,CG,Special,Special,5.07,3.29388,-1.77612,159,121,75,-46,108.5,60.1,-48.4,-0.831,-3.611,2.78,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.295029,0.00170814,0.516381 beta-lactamase_A40P,beta-lactamase_40,TEM-1,beta-lactamase,P62593,0.516389,NO,40,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.402,-3.856,2.454,4.9697,0.155,S,B,1.2,0.21,1.714,,73.78,OHB,-1.40267,0.221079,0.00490026,0.516389 WW_domain_N191H,WW_domain_191,Yap65,WW_domain,P46937,0.516543,NO,191,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-1.519,-4.114,2.595,5.96016,,,,,,5.117,,66.07,HPB,-1.554,0.153962,0.00270999,0.516543 beta-lactamase_2500_V82F,beta-lactamase_2500_82,TEM-1,beta-lactamase_2500,P62593,0.516561,NO,82,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.325,-3.991,2.666,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.361275,0.00397046,0.516561 kka2_1:2_E59G,kka2_1:2_59,Kka2,kka2_1:2,P00552,0.516627,NO,59,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-0.952,-3.43,2.478,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.295029,0.00280355,0.516627 kka2_1:2_T51F,kka2_1:2_51,Kka2,kka2_1:2,P00552,0.516652,NO,51,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.199,-4.265,2.066,,0.05,E,B,0.22,-0.05,13.165,13.165,63.64,BPA,-1.76767,0.295029,0.00628861,0.516652 beta-lactamase_625_R202F,beta-lactamase_625_202,TEM-1,beta-lactamase_625,P62593,0.516673,NO,202,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.292,-4.334,3.042,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.213352,0.00321899,0.516673 beta-lactamase_G248A,beta-lactamase_248,TEM-1,beta-lactamase,P62593,0.516727,NO,248,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.794,-2.642,0.848,4.69798,,E,b,0.23,-0.43,1.782,,61.19,HOO,-1.52867,0.221079,0.00428493,0.516727 beta-lactamase_2500_E87Y,beta-lactamase_2500_87,TEM-1,beta-lactamase_2500,P62593,0.516741,NO,87,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.421,-4.262,2.841,,0.048,,B,1.04,0.92,17.923,17.923,64.69,PAP,-1.969,0.361275,0.00337888,0.516741 kka2_1:2_L259I,kka2_1:2_259,Kka2,kka2_1:2,P00552,0.51679,NO,259,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.088,-3.1,2.012,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.295029,0.0206964,0.51679 kka2_1:4_I207Q,kka2_1:4_207,Kka2,kka2_1:4,P00552,0.516834,NO,207,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.175,-4.367,3.192,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.168804,0.00611824,0.516834 beta-lactamase_625_Y44H,beta-lactamase_625_44,TEM-1,beta-lactamase_625,P62593,0.516866,NO,44,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-2.547,-4.769,2.222,,,E,B,0.21,-0.45,2.371,,73.78,OHH,-1.86267,0.213352,0.00426364,0.516866 beta-lactamase_39_D129N,beta-lactamase_39_129,TEM-1,beta-lactamase_39,P62593,0.516959,NO,129,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.816,-3.272,2.456,,,,B,0.75,-0.69,0.56,,34.97,PAP,-0.818,0.0495842,0.00109178,0.516959 beta-lactamase_I93N,beta-lactamase_93,TEM-1,beta-lactamase,P62593,0.516999,NO,93,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.401,-4.175,2.774,5.74695,0.128,E,B,0.77,0.44,1.757,,67.83,BHB,-1.873,0.221079,0.00527066,0.516999 kka2_1:1_E160K,kka2_1:1_160,Kka2,kka2_1:1,P00552,0.517042,NO,160,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.683,-2.805,1.122,,0.989,G,A,1.04,2.28,0.273,,71.59,AAA,-1.36133,0.520039,0.00935762,0.517042 beta-lactamase_A34N,beta-lactamase_34,TEM-1,beta-lactamase,P62593,0.517043,NO,34,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.059,-3.965,1.906,4.9129,,H,A,0.75,-0.54,3.614,,73.78,AHA,-1.74967,0.221079,0.00407913,0.517043 kka2_1:8_W236Q,kka2_1:8_236,Kka2,kka2_1:8,P00552,0.517265,NO,236,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-1.363,-4.284,2.921,,0.303,H,A,1.51,-0.76,1.87,,48.48,AHH,-1.81267,0.100394,0.0088796,0.517265 kka2_1:8_W236Q,kka2_1:8_236,Kka2,kka2_1:8,P00552,0.517265,NO,236,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-1.363,-4.284,2.921,,0.303,H,A,1.51,-0.76,1.87,,48.48,AHH,-1.81267,0.100394,0.0088796,0.517265 beta-lactamase_E35I,beta-lactamase_35,TEM-1,beta-lactamase,P62593,0.517283,NO,35,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-0.869,-4.036,3.167,5.10723,0.15,H,A,0.52,0.21,1.081,,46.85,HAA,-1.88667,0.221079,0.00174441,0.517283 kka2_1:1_L158R,kka2_1:1_158,Kka2,kka2_1:1,P00552,0.51744,NO,158,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.947,-4.189,2.242,,0.095,.,B,0.55,0.77,7.588,,63.64,AHA,-1.25333,0.520039,0.00529068,0.51744 kka2_1:4_D157E,kka2_1:4_157,Kka2,kka2_1:4,P00552,0.517441,NO,157,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.993,-2.48,1.487,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.168804,0.0042313,0.517441 beta-lactamase_2500_V214W,beta-lactamase_2500_214,TEM-1,beta-lactamase_2500,P62593,0.517485,NO,214,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.299,-5.33,4.031,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.361275,0.00628442,0.517485 beta-lactamase_2500_T263Y,beta-lactamase_2500_263,TEM-1,beta-lactamase_2500,P62593,0.517606,NO,263,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.361275,0.0110582,0.517606 kka2_1:4_R66H,kka2_1:4_66,Kka2,kka2_1:4,P00552,0.517609,NO,66,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-0.922,-4.322,3.4,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.168804,0.00161025,0.517609 kka2_1:4_A119S,kka2_1:4_119,Kka2,kka2_1:4,P00552,0.517617,NO,119,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.073,-2.181,1.108,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.168804,0.00441074,0.517617 beta-lactamase_0_M115K,beta-lactamase_0_115,TEM-1,beta-lactamase_0,P62593,0.517621,NO,115,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.389,-3.553,2.164,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.0500837,0.0034337,0.517621 kka2_1:1_S54T,kka2_1:1_54,Kka2,kka2_1:1,P00552,0.517732,NO,54,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.471,-2.979,0.508,,0.408,S,b,0.27,1.01,6.085,,71.59,HPO,-2.259,0.520039,0.00782867,0.517732 kka2_1:4_V80G,kka2_1:4_80,Kka2,kka2_1:4,P00552,0.517749,NO,80,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.144,-3.627,2.483,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.168804,0.00488211,0.517749 kka2_1:4_W15P,kka2_1:4_15,Kka2,kka2_1:4,P00552,0.517761,NO,15,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-1.392,-4.349,2.957,,0.01,G,A,0.47,0.15,0.943,,52.27,HHH,-2.10533,0.168804,0.00585505,0.517761 kka2_1:2_V214A,kka2_1:2_214,Kka2,kka2_1:2,P00552,0.517785,NO,214,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.261,-3.113,1.852,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.295029,0.00692782,0.517785 beta-lactamase_625_N134C,beta-lactamase_625_134,TEM-1,beta-lactamase_625,P62593,0.517898,NO,134,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-0.879,-5.113,4.234,,0.138,H,A,0.61,-0.6,3.776,,53.15,HPH,-1.02233,0.213352,0.000644786,0.517898 beta-lactamase_156_G236M,beta-lactamase_156_236,TEM-1,beta-lactamase_156,P62593,0.517933,NO,236,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.784,-4.869,4.085,,0.241,,b,0.29,-0.59,1.883,,64.69,HOO,-1.025,0.111618,0.00162372,0.517933 gb1_K254A,gb1_254,gb1,gb1,P06654,0.517953,NO,254,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.748,-2.943,1.195,,,,,,,1.793,,37.28,ABH,-2.195,0.177985,0.00622711,0.517953 PSD95pdz3_I389P,PSD95pdz3_389,PSD95pdz3,PSD95pdz3,P31016,0.517957,NO,389,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.628,-3.785,2.157,5.15116,,,,,14.8038,1.498,,87.71,HHH,-1.52167,0.0758425,0.00148097,0.517957 kka2_1:4_N58E,kka2_1:4_58,Kka2,kka2_1:4,P00552,0.517969,NO,58,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-2.641,-3.612,0.971,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.168804,0.00793425,0.517969 beta-lactamase_2500_T187K,beta-lactamase_2500_187,TEM-1,beta-lactamase_2500,P62593,0.518045,NO,187,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.401,-3.578,2.177,,0.007,H,A,0.22,-1.19,3.91,,67.48,PPH,-1.69633,0.361275,0.00491782,0.518045 beta-lactamase_156_L192E,beta-lactamase_156_192,TEM-1,beta-lactamase_156,P62593,0.518047,NO,192,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.254,-3.893,2.639,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.111618,0.00558728,0.518047 kka2_1:4_D250G,kka2_1:4_250,Kka2,kka2_1:4,P00552,0.518066,NO,250,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.015,-3.27,2.255,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.168804,0.0177103,0.518066 kka2_1:2_Q163G,kka2_1:2_163,Kka2,kka2_1:2,P00552,0.518081,NO,163,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.162,-3.698,1.536,,0.58,T,B,0.64,1.85,3.888,,64.02,BPO,-1.78333,0.295029,0.00719507,0.518081 beta-lactamase_L197D,beta-lactamase_197,TEM-1,beta-lactamase,P62593,0.518119,NO,197,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.853,-4.107,3.254,5.19172,0.007,S,B,1.3,0.33,1.756,,60.14,HHP,-1.833,0.221079,0.00144602,0.518119 WW_domain_W177R,WW_domain_177,Yap65,WW_domain,P46937,0.518188,NO,177,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-1.198,-3.935,2.737,5.18137,,,,,,,,,OHA,-1.197,0.153962,0.00198549,0.518188 kka2_1:2_D127G,kka2_1:2_127,Kka2,kka2_1:2,P00552,0.518276,NO,127,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.364,-3.377,2.013,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.295029,0.00660501,0.518276 beta-lactamase_M115E,beta-lactamase_115,TEM-1,beta-lactamase,P62593,0.518354,NO,115,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.389,-3.76,2.371,4.89743,0.019,E,B,1.3,0.08,1.236,,69.58,OHP,-1.25433,0.221079,0.0034337,0.518354 beta-lactamase_156_T131D,beta-lactamase_156_131,TEM-1,beta-lactamase_156,P62593,0.518373,NO,131,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.328,-3.605,2.277,,,H,A,0.22,-0.69,2.031,,67.48,PPH,-1.00867,0.111618,0.00345886,0.518373 WW_domain_H192I,WW_domain_192,Yap65,WW_domain,P46937,0.518387,NO,192,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-1.739,-2.443,0.704,5.20314,,,,,,1.458,,78.57,PBH,-1.75033,0.153962,0.00436368,0.518387 beta-lactamase_E35K,beta-lactamase_35,TEM-1,beta-lactamase,P62593,0.518442,NO,35,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-0.869,-3.075,2.206,5.10723,0.15,H,A,0.52,0.21,1.081,,46.85,HAA,-1.88667,0.221079,0.00174441,0.518442 beta-lactamase_I125S,beta-lactamase_125,TEM-1,beta-lactamase,P62593,0.518483,NO,125,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.441,-2.843,1.402,5.23481,,H,A,2.82,-0.7,2.301,,63.29,HHP,-1.248,0.221079,0.00383964,0.518483 kka2_1:1_I196D,kka2_1:1_196,Kka2,kka2_1:1,P00552,0.51851,NO,196,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-2.115,-4.156,2.041,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.520039,0.0107273,0.51851 kka2_1:4_R140P,kka2_1:4_140,Kka2,kka2_1:4,P00552,0.518668,NO,140,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.351,-3.937,2.586,,0.12,H,A,1.2,0.2,2.561,,53.03,BBH,-1.885,0.168804,0.00430167,0.518668 kka2_1:2_D159V,kka2_1:2_159,Kka2,kka2_1:2,P00552,0.518819,NO,159,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.82,-3.816,2.996,,0.28,.,B,0.75,1.25,0.899,,48.11,HAA,-1.48333,0.295029,0.0030485,0.518819 kka2_1:1_F240Q,kka2_1:1_240,Kka2,kka2_1:1,P00552,0.518832,NO,240,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-0.911,-4.376,3.465,,,H,A,1.62,-1.21,5.798,,50.38,BHH,-1.67267,0.520039,0.00552543,0.518832 beta-lactamase_625_T263W,beta-lactamase_625_263,TEM-1,beta-lactamase_625,P62593,0.51884,NO,263,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.213352,0.0110582,0.51884 kka2_1:2_L57D,kka2_1:2_57,Kka2,kka2_1:2,P00552,0.51897,NO,57,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.898,-4.048,2.15,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.295029,0.00723769,0.51897 beta-lactamase_0_I171Q,beta-lactamase_0_171,TEM-1,beta-lactamase_0,P62593,0.518987,NO,171,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-2.431,-3.168,0.737,,0.361,,B,0.48,0.53,16.954,16.954,77.62,HHO,-1.55533,0.0500837,0.00623355,0.518987 kka2_1:1_R202G,kka2_1:1_202,Kka2,kka2_1:1,P00552,0.519122,NO,202,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.761,-2.403,0.642,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.520039,0.00696498,0.519122 kka2_1:1_D190Y,kka2_1:1_190,Kka2,kka2_1:1,P00552,0.519136,NO,190,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.708,-4.416,3.708,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.520039,0.00247989,0.519136 beta-lactamase_D174Y,beta-lactamase_174,TEM-1,beta-lactamase,P62593,0.519212,NO,174,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.738,-4.387,3.649,5.44133,0.238,,B,1.22,-0.1,,,,PAA,-1.91233,0.221079,0.00125633,0.519212 kka2_1:8_H124K,kka2_1:8_124,Kka2,kka2_1:8,P00552,0.519225,NO,124,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-0.84,-3.485,2.645,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.100394,0.00211296,0.519225 kka2_1:8_H124K,kka2_1:8_124,Kka2,kka2_1:8,P00552,0.519225,NO,124,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-0.84,-3.485,2.645,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.100394,0.00211296,0.519225 beta-lactamase_R220C,beta-lactamase_220,TEM-1,beta-lactamase,P62593,0.519324,NO,220,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-0.942,-5.009,4.067,5.65995,0.295,I,A,0.68,-0.76,2.164,,74.48,HBP,-1.33633,0.221079,0.00232421,0.519324 beta-lactamase_2500_R81C,beta-lactamase_2500_81,TEM-1,beta-lactamase_2500,P62593,0.519331,NO,81,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.466,-5.147,3.681,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.361275,0.00499763,0.519331 kka2_1:8_L260Q,kka2_1:8_260,Kka2,kka2_1:8,P00552,0.519331,NO,260,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.741,-4.153,3.412,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.100394,0.0233782,0.519331 kka2_1:8_L260Q,kka2_1:8_260,Kka2,kka2_1:8,P00552,0.519331,NO,260,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.741,-4.153,3.412,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.100394,0.0233782,0.519331 kka2_1:2_P76M,kka2_1:2_76,Kka2,kka2_1:2,P00552,0.519333,NO,76,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.449,-4.717,3.268,,0.331,.,B,0.52,-0.41,0.345,,63.64,HOO,-1.662,0.295029,0.00625685,0.519333 kka2_1:2_E262C,kka2_1:2_262,Kka2,kka2_1:2,P00552,0.519487,NO,262,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-0.829,-5.339,4.51,,0.059,G,A,1.04,-0.18,2.383,,42.42,AAH,-0.816,0.295029,0.0191586,0.519487 kka2_1:2_E262W,kka2_1:2_262,Kka2,kka2_1:2,P00552,0.519487,NO,262,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-0.829,-5.349,4.52,,0.059,G,A,1.04,-0.18,2.383,,42.42,AAH,-0.816,0.295029,0.0191586,0.519487 kka2_1:2_L212Q,kka2_1:2_212,Kka2,kka2_1:2,P00552,0.519518,NO,212,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.904,-4.175,3.271,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.295029,0.0031426,0.519518 kka2_1:2_E63G,kka2_1:2_63,Kka2,kka2_1:2,P00552,0.519586,NO,63,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-0.762,-3.386,2.624,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.295029,0.00118399,0.519586 kka2_1:1_V46Q,kka2_1:1_46,Kka2,kka2_1:1,P00552,0.519656,NO,46,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-2.62,-4.138,1.518,,0.192,.,B,0.44,-1.12,20.149,20.149,92.05,OHH,-1.88633,0.520039,0.00631301,0.519656 beta-lactamase_T131E,beta-lactamase_131,TEM-1,beta-lactamase,P62593,0.519726,NO,131,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.328,-3.523,2.195,5.0548,,H,A,0.53,-0.69,3.306,,67.48,PPH,-1.00867,0.221079,0.00345886,0.519726 kka2_1:1_R173A,kka2_1:1_173,Kka2,kka2_1:1,P00552,0.519735,NO,173,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.407,-2.391,-0.016,,0.308,H,A,0.16,-0.13,14.756,14.756,65.53,HBH,-1.70533,0.520039,0.00784999,0.519735 beta-lactamase_39_E164D,beta-lactamase_39_164,TEM-1,beta-lactamase_39,P62593,0.519976,NO,164,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-0.948,-2.949,2.001,,0.011,T,B,1.04,-0.4,0.664,,64.69,HAO,-1.388,0.0495842,0.00137286,0.519976 kka2_1:1_A150M,kka2_1:1_150,Kka2,kka2_1:1,P00552,0.520014,NO,150,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.949,-4.623,3.674,,0.544,T,A,0.46,1.34,2.333,,63.26,AHO,-1.272,0.520039,0.0045009,0.520014 beta-lactamase_2500_C121L,beta-lactamase_2500_121,TEM-1,beta-lactamase_2500,P62593,0.520015,NO,121,C,L,CL,Special,Hydrophobic,5.07,9.7088,4.6388,198,121,131,10,108.5,166.7,58.2,-0.953,-3.182,2.229,,,H,A,0.46,-0.81,1.174,,63.29,HOP,-1.46767,0.361275,0.000744322,0.520015 beta-lactamase_156_S104Q,beta-lactamase_156_104,TEM-1,beta-lactamase_156,P62593,0.520061,NO,104,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.015,-3.815,2.8,,0.04,,b,0.27,0.57,4.02,,63.29,HPO,-1.05267,0.111618,0.00218083,0.520061 kka2_1:4_G213A,kka2_1:4_213,Kka2,kka2_1:4,P00552,0.52009,NO,213,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.596,-2.881,2.285,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.168804,0.00187654,0.52009 beta-lactamase_2500_A34Y,beta-lactamase_2500_34,TEM-1,beta-lactamase_2500,P62593,0.520092,NO,34,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.059,-4.077,2.018,,,H,A,0.46,-0.54,2.921,,73.78,AHA,-1.74967,0.361275,0.00407913,0.520092 beta-lactamase_F14Q,beta-lactamase_14,TEM-1,beta-lactamase,P62593,0.520102,NO,14,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-2.736,-4.194,1.458,,,,,,,1.537,,93.01,HHH,-2.26133,0.221079,0.00277095,0.520102 beta-lactamase_2500_A211P,beta-lactamase_2500_211,TEM-1,beta-lactamase_2500,P62593,0.520122,NO,211,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.896,-3.94,2.044,,0.369,T,A,0.46,-0.69,2.061,,77.62,AHA,-1.94633,0.361275,0.00648183,0.520122 beta-lactamase_39_T158P,beta-lactamase_39_158,TEM-1,beta-lactamase_39,P62593,0.520142,NO,158,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.116,-2.676,1.56,,0.036,,B,0.22,-0.85,2.755,,69.58,HPB,-1.269,0.0495842,0.00341825,0.520142 beta-lactamase_L10D,beta-lactamase_10,TEM-1,beta-lactamase,P62593,0.520142,NO,10,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.623,-3.873,2.25,,,,,,,2.467,,65.38,HHH,-1.83833,0.221079,0.00296968,0.520142 beta-lactamase_2500_M184A,beta-lactamase_2500_184,TEM-1,beta-lactamase_2500,P62593,0.520236,NO,184,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.593,-2.223,0.63,,,H,A,0.55,-0.87,2.893,,62.94,HHH,-1.41,0.361275,0.00356019,0.520236 kka2_1:2_M116N,kka2_1:2_116,Kka2,kka2_1:2,P00552,0.520236,NO,116,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-2.482,-4.236,1.754,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.295029,0.00745147,0.520236 beta-lactamase_A215F,beta-lactamase_215,TEM-1,beta-lactamase,P62593,0.520254,NO,215,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.503,-4.278,2.775,4.82164,,,a,0.75,-0.93,3.583,,74.48,HHO,-1.42633,0.221079,0.00544007,0.520254 beta-lactamase_625_D174M,beta-lactamase_625_174,TEM-1,beta-lactamase_625,P62593,0.520277,NO,174,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.738,-4.93,4.192,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.213352,0.00125633,0.520277 beta-lactamase_2500_P105Q,beta-lactamase_2500_105,TEM-1,beta-lactamase_2500,P62593,0.520351,NO,105,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.813,-3.897,3.084,,0.226,T,A,0.52,0.8,3.1,,63.29,POH,-1.01533,0.361275,0.0011981,0.520351 beta-lactamase_2500_Y103S,beta-lactamase_2500_103,TEM-1,beta-lactamase_2500,P62593,0.520364,NO,103,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-1.33,-3.594,2.264,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.361275,0.00443048,0.520364 beta-lactamase_W208H,beta-lactamase_208,TEM-1,beta-lactamase,P62593,0.520389,NO,208,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-0.818,-4.68,3.862,5.26277,0.067,H,A,0.99,-0.65,,,,AHH,-1.44133,0.221079,0.00126609,0.520389 beta-lactamase_W208I,beta-lactamase_208,TEM-1,beta-lactamase,P62593,0.52045,NO,208,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-0.818,-4.01,3.192,5.26277,0.067,H,A,0.99,-0.65,,,,AHH,-1.44133,0.221079,0.00126609,0.52045 beta-lactamase_625_M66Y,beta-lactamase_625_66,TEM-1,beta-lactamase_625,P62593,0.520452,NO,66,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.362,-4.034,2.672,,0.013,,A,0.55,-0.7,1.659,,73.08,OHH,-1.49567,0.213352,0.00412876,0.520452 kka2_1:1_Y244C,kka2_1:1_244,Kka2,kka2_1:1,P00552,0.520487,NO,244,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-0.775,-4.89,4.115,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.520039,0.00453187,0.520487 beta-lactamase_2500_L55A,beta-lactamase_2500_55,TEM-1,beta-lactamase_2500,P62593,0.520504,NO,55,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.86,-2.512,0.652,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.361275,0.00403741,0.520504 kka2_1:4_R122P,kka2_1:4_122,Kka2,kka2_1:4,P00552,0.520521,NO,122,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.175,-3.279,1.104,,0.487,H,A,0.16,0.26,16.436,16.436,71.59,BBH,-1.53833,0.168804,0.00736512,0.520521 kka2_1:2_R239W,kka2_1:2_239,Kka2,kka2_1:2,P00552,0.520536,NO,239,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.949,-5.592,2.643,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.295029,0.00835326,0.520536 beta-lactamase_2500_M270C,beta-lactamase_2500_270,TEM-1,beta-lactamase_2500,P62593,0.520551,NO,270,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.723,,,,0.422,H,A,1.59,1.15,2.029,,64.34,PHA,-1.70933,0.361275,0.00767762,0.520551 beta-lactamase_156_G240F,beta-lactamase_156_240,TEM-1,beta-lactamase_156,P62593,0.520579,NO,240,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.111618,0.00591201,0.520579 beta-lactamase_A40Y,beta-lactamase_40,TEM-1,beta-lactamase,P62593,0.520614,NO,40,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.402,-4.322,2.92,4.9697,0.155,S,B,1.2,0.21,1.714,,73.78,OHB,-1.40267,0.221079,0.00490026,0.520614 kka2_1:2_L158N,kka2_1:2_158,Kka2,kka2_1:2,P00552,0.520715,NO,158,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.947,-4.203,2.256,,0.095,,B,1.59,0.77,7.588,,63.64,AHA,-1.25333,0.295029,0.00529068,0.520715 beta-lactamase_T179A,beta-lactamase_179,TEM-1,beta-lactamase,P62593,0.520886,NO,179,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.085,-2.334,1.249,5.07116,,E,B,0.8,-1.38,1.859,,73.08,PPH,-1.557,0.221079,0.00226045,0.520886 beta-lactamase_625_T263G,beta-lactamase_625_263,TEM-1,beta-lactamase_625,P62593,0.521061,NO,263,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.031,-3.618,1.587,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.213352,0.0110582,0.521061 kka2_1:2_G164P,kka2_1:2_164,Kka2,kka2_1:2,P00552,0.521094,NO,164,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.869,-3.944,3.075,,0.862,T,l,0.75,1.45,1.539,,64.39,POH,-1.828,0.295029,0.00442091,0.521094 kka2_1:2_P128W,kka2_1:2_128,Kka2,kka2_1:2,P00552,0.521103,NO,128,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.922,-3.525,1.603,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.295029,0.00774689,0.521103 beta-lactamase_2500_C75S,beta-lactamase_2500_75,TEM-1,beta-lactamase_2500,P62593,0.521126,NO,75,C,S,CS,Special,Polar,5.07,5.68,0.61,112,121,105,-16,108.5,89,-19.5,-1.245,-2.597,1.352,,,H,A,0.46,-0.87,0.844,,50,HOO,-1.24333,0.361275,0.0034616,0.521126 gb1_N261C,gb1_261,gb1,gb1,P06654,0.52114,NO,261,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-1.863,-4.654,2.791,,,,,,,1.191,,44.87,HPA,-2.16033,0.177985,0.0061875,0.52114 beta-lactamase_2500_N130S,beta-lactamase_2500_130,TEM-1,beta-lactamase_2500,P62593,0.521171,NO,130,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-0.798,-2.936,2.138,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.361275,0.000683376,0.521171 beta-lactamase_2500_P105A,beta-lactamase_2500_105,TEM-1,beta-lactamase_2500,P62593,0.521172,NO,105,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.813,-3.041,2.228,,0.226,T,A,0.52,0.8,3.1,,63.29,POH,-1.01533,0.361275,0.0011981,0.521172 kka2_1:2_V75H,kka2_1:2_75,Kka2,kka2_1:2,P00552,0.521172,NO,75,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-2.06,-4.952,2.892,,0.042,.,B,0.44,-0.2,2.815,,71.59,OHO,-1.563,0.295029,0.00693733,0.521172 kka2_1:8_L170I,kka2_1:8_170,Kka2,kka2_1:8,P00552,0.521173,NO,170,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.28,-2.562,1.282,,0.029,H,A,1.59,0.11,1.453,,62.5,AHH,-1.534,0.100394,0.00730791,0.521173 kka2_1:8_L170I,kka2_1:8_170,Kka2,kka2_1:8,P00552,0.521173,NO,170,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.28,-2.562,1.282,,0.029,H,A,1.59,0.11,1.453,,62.5,AHH,-1.534,0.100394,0.00730791,0.521173 beta-lactamase_625_P224V,beta-lactamase_625_224,TEM-1,beta-lactamase_625,P62593,0.521196,NO,224,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.893,-3.599,2.706,,0.383,,B,0.52,-0.3,1.35,,74.48,HOH,-1.26433,0.213352,0.00189564,0.521196 beta-lactamase_2500_L248W,beta-lactamase_2500_248,TEM-1,beta-lactamase_2500,P62593,0.521208,NO,248,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.361275,0.00428493,0.521208 beta-lactamase_156_L191G,beta-lactamase_156_191,TEM-1,beta-lactamase_156,P62593,0.52121,NO,191,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.087,-3.655,2.568,,,H,A,0.55,0.09,1.372,,63.29,BHH,-1.445,0.111618,0.00263549,0.52121 beta-lactamase_625_R63G,beta-lactamase_625_63,TEM-1,beta-lactamase_625,P62593,0.521266,NO,63,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-0.943,-3.426,2.483,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.213352,0.00126938,0.521266 beta-lactamase_I259W,beta-lactamase_259,TEM-1,beta-lactamase,P62593,0.521355,NO,259,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.522,-5.403,3.881,5.28457,,E,B,1,-0.8,1.24,,64.34,HHH,-1.53267,0.221079,0.0070773,0.521355 beta-lactamase_625_V117N,beta-lactamase_625_117,TEM-1,beta-lactamase_625,P62593,0.521366,NO,117,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.53,-4.224,2.694,,,H,A,0.44,-0.34,1.23,,65.03,PHB,-1.741,0.213352,0.00467906,0.521366 kka2_1:2_W236A,kka2_1:2_236,Kka2,kka2_1:2,P00552,0.521372,NO,236,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-1.363,-2.534,1.171,,0.303,H,A,1.51,-0.76,5.58,,48.48,AHH,-1.81267,0.295029,0.0088796,0.521372 kka2_1:1_L212P,kka2_1:1_212,Kka2,kka2_1:1,P00552,0.521411,NO,212,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.904,-4.095,3.191,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.520039,0.0031426,0.521411 kka2_1:2_V185R,kka2_1:2_185,Kka2,kka2_1:2,P00552,0.521419,NO,185,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.045,-4.178,3.133,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.295029,0.00367031,0.521419 beta-lactamase_156_I45W,beta-lactamase_156_45,TEM-1,beta-lactamase_156,P62593,0.521443,NO,45,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-2.421,-5.294,2.873,,,E,B,0.48,-0.3,2.256,,77.62,HHA,-2.30267,0.111618,0.00452842,0.521443 beta-lactamase_2500_F149C,beta-lactamase_2500_149,TEM-1,beta-lactamase_2500,P62593,0.521453,NO,149,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.299,-4.94,3.641,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.361275,0.00418462,0.521453 WW_domain_S184P,WW_domain_184,Yap65,WW_domain,P46937,0.521494,NO,184,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.363,-3.495,2.132,5.06696,,,,,,,,,PPO,-1.39133,0.153962,0.00231095,0.521494 kka2_1:4_P132W,kka2_1:4_132,Kka2,kka2_1:4,P00552,0.521637,NO,132,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.775,-5.574,4.799,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.168804,0.0018489,0.521637 beta-lactamase_2500_D212K,beta-lactamase_2500_212,TEM-1,beta-lactamase_2500,P62593,0.521649,NO,212,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.624,-3.581,1.957,,0.037,,b,0.75,-0.58,12.482,,74.48,HAB,-1.77667,0.361275,0.00644302,0.521649 beta-lactamase_625_L120F,beta-lactamase_625_120,TEM-1,beta-lactamase_625,P62593,0.521677,NO,120,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.044,-2.785,1.741,,,H,A,0.55,-1.13,7.813,,64.69,AHO,-1.13633,0.213352,0.00143563,0.521677 kka2_1:8_C77F,kka2_1:8_77,Kka2,kka2_1:8,P00552,0.521808,NO,77,C,F,CF,Special,Hydrophobic,5.07,3.32051,-1.74949,205,121,165,44,108.5,189.9,81.4,-1.477,-4.235,2.758,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.100394,0.00441216,0.521808 kka2_1:8_C77F,kka2_1:8_77,Kka2,kka2_1:8,P00552,0.521808,NO,77,C,F,CF,Special,Hydrophobic,5.07,3.32051,-1.74949,205,121,165,44,108.5,189.9,81.4,-1.477,-4.235,2.758,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.100394,0.00441216,0.521808 beta-lactamase_R220F,beta-lactamase_220,TEM-1,beta-lactamase,P62593,0.521845,NO,220,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-0.942,-4.29,3.348,5.65995,0.295,I,A,0.68,-0.76,2.164,,74.48,HBP,-1.33633,0.221079,0.00232421,0.521845 beta-lactamase_625_R242A,beta-lactamase_625_242,TEM-1,beta-lactamase_625,P62593,0.521875,NO,242,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.213352,0.00452879,0.521875 beta-lactamase_L218N,beta-lactamase_218,TEM-1,beta-lactamase,P62593,0.521881,NO,218,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.391,-3.851,2.46,4.88972,,I,b,2.89,-0.53,12.788,12.788,74.48,OHH,-1.58867,0.221079,0.00618274,0.521881 beta-lactamase_625_A123L,beta-lactamase_625_123,TEM-1,beta-lactamase_625,P62593,0.521946,NO,123,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.834,-3.096,2.262,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.213352,0.0010157,0.521946 beta-lactamase_A84P,beta-lactamase_84,TEM-1,beta-lactamase,P62593,0.522072,NO,84,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.651,-3.933,2.282,5.28927,0.65,T,A,0.52,0.96,1.863,,68.18,AHO,-1.24267,0.221079,0.00503822,0.522072 beta-lactamase_2500_I277Y,beta-lactamase_2500_277,TEM-1,beta-lactamase_2500,P62593,0.52216,NO,277,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.361275,0.0169305,0.52216 kka2_1:1_G10A,kka2_1:1_10,Kka2,kka2_1:1,P00552,0.522193,NO,10,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.921,-3.11,1.189,,,,,,,1.862,,71.59,HOP,-2.10733,0.520039,0.00289233,0.522193 kka2_1:2_P109S,kka2_1:2_109,Kka2,kka2_1:2,P00552,0.522264,NO,109,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.412,-2.854,1.442,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.295029,0.0070929,0.522264 kka2_1:4_V49K,kka2_1:4_49,Kka2,kka2_1:4,P00552,0.522368,NO,49,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.614,-3.819,2.205,,,E,B,0.44,-0.77,1.233,,64.39,HHB,-1.3,0.168804,0.00615685,0.522368 kka2_1:1_D190C,kka2_1:1_190,Kka2,kka2_1:1,P00552,0.522669,NO,190,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.708,-5.115,4.407,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.520039,0.00247989,0.522669 beta-lactamase_156_L205Y,beta-lactamase_156_205,TEM-1,beta-lactamase_156,P62593,0.52268,NO,205,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.922,-3.727,2.805,,,H,A,0.55,-0.46,0.678,,42.31,PHH,-1.57767,0.111618,0.00255802,0.52268 beta-lactamase_2500_L150W,beta-lactamase_2500_150,TEM-1,beta-lactamase_2500,P62593,0.522721,NO,150,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.326,-5.247,3.921,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.361275,0.00463171,0.522721 beta-lactamase_P65Q,beta-lactamase_65,TEM-1,beta-lactamase,P62593,0.522784,NO,65,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.894,-3.954,3.06,5.59094,0.098,E,B,0.23,-0.62,0.623,,40.56,HOH,-1.03233,0.221079,0.00152776,0.522784 beta-lactamase_2500_A247G,beta-lactamase_2500_247,TEM-1,beta-lactamase_2500,P62593,0.522791,NO,247,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.361275,0.00611275,0.522791 kka2_1:8_R66E,kka2_1:8_66,Kka2,kka2_1:8,P00552,0.522849,NO,66,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-0.922,-3.242,2.32,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.100394,0.00161025,0.522849 kka2_1:8_R66E,kka2_1:8_66,Kka2,kka2_1:8,P00552,0.522849,NO,66,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-0.922,-3.242,2.32,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.100394,0.00161025,0.522849 beta-lactamase_625_K30D,beta-lactamase_625_30,TEM-1,beta-lactamase_625,P62593,0.522952,NO,30,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-2.307,-3.567,1.26,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.213352,0.00448593,0.522952 kka2_1:2_V185C,kka2_1:2_185,Kka2,kka2_1:2,P00552,0.523005,NO,185,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.045,-3.114,2.069,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.295029,0.00367031,0.523005 beta-lactamase_2500_F64Y,beta-lactamase_2500_64,TEM-1,beta-lactamase_2500,P62593,0.523073,NO,64,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-0.841,-3.037,2.196,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.361275,0.000947691,0.523073 kka2_1:8_D90I,kka2_1:8_90,Kka2,kka2_1:8,P00552,0.523074,NO,90,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.459,-3.293,0.834,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.100394,0.00583842,0.523074 kka2_1:8_D90I,kka2_1:8_90,Kka2,kka2_1:8,P00552,0.523074,NO,90,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.459,-3.293,0.834,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.100394,0.00583842,0.523074 beta-lactamase_2500_P250G,beta-lactamase_2500_250,TEM-1,beta-lactamase_2500,P62593,0.523102,NO,250,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.361275,0.00550899,0.523102 beta-lactamase_I125N,beta-lactamase_125,TEM-1,beta-lactamase,P62593,0.523234,NO,125,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.441,-4.089,2.648,5.23481,,H,A,2.82,-0.7,2.301,,63.29,HHP,-1.248,0.221079,0.00383964,0.523234 kka2_1:1_A110Q,kka2_1:1_110,Kka2,kka2_1:1,P00552,0.523298,NO,110,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.064,-2.476,0.412,,0.175,H,A,1.04,-1.19,11.755,,71.59,OHA,-1.91867,0.520039,0.00759851,0.523298 beta-lactamase_2500_K232R,beta-lactamase_2500_232,TEM-1,beta-lactamase_2500,P62593,0.523362,NO,232,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.012,-1.888,0.876,,,E,B,2.34,-1.1,3.048,,65.03,ABP,-1.238,0.361275,0.00313441,0.523362 beta-lactamase_R59E,beta-lactamase_59,TEM-1,beta-lactamase,P62593,0.523391,NO,59,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.345,-3.322,1.977,5.49837,0.329,S,L,0.68,-0.09,1.806,,73.08,HBO,-2.24267,0.221079,0.00318082,0.523391 kka2_1:2_I115K,kka2_1:2_115,Kka2,kka2_1:2,P00552,0.523431,NO,115,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.606,-3.902,2.296,,0.105,H,A,0.48,-1.18,0.878,,65.53,PHH,-2.205,0.295029,0.00836567,0.523431 beta-lactamase_625_V29P,beta-lactamase_625_29,TEM-1,beta-lactamase_625,P62593,0.523466,NO,29,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-2.856,-3.853,0.997,,0.733,H,A,0.44,-0.78,1.931,,93.01,HHB,-2.24733,0.213352,0.00318969,0.523466 beta-lactamase_2500_L55G,beta-lactamase_2500_55,TEM-1,beta-lactamase_2500,P62593,0.523477,NO,55,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.86,-3.665,1.805,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.361275,0.00403741,0.523477 beta-lactamase_M115K,beta-lactamase_115,TEM-1,beta-lactamase,P62593,0.523562,NO,115,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.389,-3.553,2.164,4.89743,0.019,E,B,1.3,0.08,1.236,,69.58,OHP,-1.25433,0.221079,0.0034337,0.523562 beta-lactamase_39_N130P,beta-lactamase_39_130,TEM-1,beta-lactamase_39,P62593,0.523702,NO,130,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-0.798,-3.88,3.082,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.0495842,0.000683376,0.523702 kka2_1:1_A87V,kka2_1:1_87,Kka2,kka2_1:1,P00552,0.523703,NO,87,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.917,-3.732,1.815,,1.039,S,L,0.46,1.57,20.738,20.738,65.53,AHO,-1.822,0.520039,0.00791281,0.523703 beta-lactamase_V117Q,beta-lactamase_117,TEM-1,beta-lactamase,P62593,0.52375,NO,117,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.53,-4.247,2.717,5.33594,,H,A,1.19,-0.34,1.182,,65.03,PHB,-1.741,0.221079,0.00467906,0.52375 beta-lactamase_2500_R273D,beta-lactamase_2500_273,TEM-1,beta-lactamase_2500,P62593,0.523772,NO,273,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.314,-3.543,1.229,,0.564,H,A,1.2,1.57,19.943,19.943,73.78,ABP,-1.841,0.361275,0.0077952,0.523772 kka2_1:1_S32I,kka2_1:1_32,Kka2,kka2_1:1,P00552,0.523927,NO,32,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-0.804,-3.814,3.01,,0.768,S,b,0.27,3.75,,,,OPA,-1.74533,0.520039,0.00149998,0.523927 kka2_1:1_H162C,kka2_1:1_162,Kka2,kka2_1:1,P00552,0.523954,NO,162,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-2.319,-5.188,2.869,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.520039,0.00616145,0.523954 kka2_1:1_A222G,kka2_1:1_222,Kka2,kka2_1:1,P00552,0.523956,NO,222,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.725,-2.936,2.211,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.520039,0.00207657,0.523956 beta-lactamase_625_M153D,beta-lactamase_625_153,TEM-1,beta-lactamase_625,P62593,0.523962,NO,153,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-3.193,-3.931,0.738,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.213352,0.00509109,0.523962 kka2_1:1_A65K,kka2_1:1_65,Kka2,kka2_1:1,P00552,0.524028,NO,65,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.744,-3.037,1.293,,0.437,H,A,0.46,-0.39,3.012,,63.64,HHB,-1.38733,0.520039,0.00709258,0.524028 kka2_1:1_I254V,kka2_1:1_254,Kka2,kka2_1:1,P00552,0.524046,NO,254,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.933,-2.29,0.357,,0.135,H,A,1.52,-0.6,1.859,,71.59,BHH,-1.668,0.520039,0.0132375,0.524046 beta-lactamase_R255E,beta-lactamase_255,TEM-1,beta-lactamase,P62593,0.52407,NO,255,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.266,-3.791,1.525,5.55882,0.141,E,B,0.68,0.38,1.199,,63.99,PBH,-2.00433,0.221079,0.00499612,0.52407 kka2_1:1_D154H,kka2_1:1_154,Kka2,kka2_1:1,P00552,0.524074,NO,154,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.876,-4.446,3.57,,0.457,.,b,0.75,1.48,0.658,,52.65,HAP,-1.52467,0.520039,0.00292633,0.524074 kka2_1:2_A110N,kka2_1:2_110,Kka2,kka2_1:2,P00552,0.52413,NO,110,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.064,-3.944,1.88,,0.175,H,A,0.46,-1.19,23.237,23.237,71.59,OHA,-1.91867,0.295029,0.00759851,0.52413 beta-lactamase_I93R,beta-lactamase_93,TEM-1,beta-lactamase,P62593,0.524133,NO,93,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.401,-4.203,2.802,5.74695,0.128,E,B,0.77,0.44,1.757,,67.83,BHB,-1.873,0.221079,0.00527066,0.524133 beta-lactamase_2500_P105H,beta-lactamase_2500_105,TEM-1,beta-lactamase_2500,P62593,0.524176,NO,105,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.813,-4.678,3.865,,0.226,T,A,0.52,0.8,3.1,,63.29,POH,-1.01533,0.361275,0.0011981,0.524176 Ubiquitin_G47E,Ubiquitin_47,Uba1,Ubiquitin,P0CG48,0.524194,NO,47,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.423,-2.467,1.044,5.24944,0.057,T,l,,-1.21,,,,HOB,-1.543,0.205827,0.000471587,0.524194 Ubiquitin_G47Q,Ubiquitin_47,Uba1,Ubiquitin,P0CG48,0.524194,NO,47,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.423,-2.927,1.504,5.24944,0.057,T,l,,-1.21,,,,HOB,-1.543,0.205827,0.000471587,0.524194 Ubiquitin_I30A,Ubiquitin_30,Uba1,Ubiquitin,P0CG48,0.524194,NO,30,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.205,-3.014,1.809,4.80264,,H,A,,-0.51,,,,BHP,-1.45133,0.205827,0.000720128,0.524194 Ubiquitin_I61W,Ubiquitin_61,Uba1,Ubiquitin,P0CG48,0.524194,NO,61,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.514,-5.362,3.848,5.19922,0.038,,B,1,-0.76,1.953,,24.53,PHP,-1.70833,0.205827,0.000738268,0.524194 Ubiquitin_L50C,Ubiquitin_50,Uba1,Ubiquitin,P0CG48,0.524194,NO,50,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.107,-4.705,3.598,5.19399,0.029,,B,,-0.92,,,,PHA,-1.52733,0.205827,0.000734242,0.524194 Ubiquitin_L73C,Ubiquitin_73,Uba1,Ubiquitin,P0CG48,0.524194,NO,73,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.801,-3.297,1.496,5.27116,0.518,,B,0.77,1,10.519,10.519,34.31,BHB,-1.858,0.205827,0.000710624,0.524194 Ubiquitin_Q41H,Ubiquitin_41,Uba1,Ubiquitin,P0CG48,0.524194,NO,41,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-1.329,-2.55,1.221,4.9201,0.017,E,B,0.12,-0.98,0.812,,30.07,PPB,-1.55067,0.205827,0.000521668,0.524194 Ubiquitin_Q49T,Ubiquitin_49,Uba1,Ubiquitin,P0CG48,0.524194,NO,49,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-1.941,-2.589,0.648,5.05026,0.403,E,B,,-0.59,,,,BPH,-1.49467,0.205827,0.000613067,0.524194 Ubiquitin_R42H,Ubiquitin_42,Uba1,Ubiquitin,P0CG48,0.524194,NO,42,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.571,-3.034,1.463,5.07805,0.244,E,B,0.68,-0.54,1.976,,72.85,PBH,-1.38967,0.205827,0.000622265,0.524194 Ubiquitin_V17W,Ubiquitin_17,Uba1,Ubiquitin,P0CG48,0.524194,NO,17,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.314,-5.215,3.901,5.26282,0.017,,B,2.78,-0.77,3.239,,71.82,AHA,-1.51833,0.205827,0.000659638,0.524194 Ubiquitin_Y59I,Ubiquitin_59,Uba1,Ubiquitin,P0CG48,0.524194,NO,59,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-1.307,-3.629,2.322,5.05599,0.072,G,A,0.43,-0.74,2.566,,24.53,AHP,-1.568,0.205827,0.000775084,0.524194 kka2_1:8_D159W,kka2_1:8_159,Kka2,kka2_1:8,P00552,0.524196,NO,159,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.82,-5.531,4.711,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.100394,0.0030485,0.524196 kka2_1:8_D159W,kka2_1:8_159,Kka2,kka2_1:8,P00552,0.524196,NO,159,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.82,-5.531,4.711,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.100394,0.0030485,0.524196 kka2_1:1_L47F,kka2_1:1_47,Kka2,kka2_1:1,P00552,0.524239,NO,47,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.265,-2.523,1.258,,0.139,E,B,0.55,-0.86,14.593,14.593,63.26,HHH,-1.77933,0.520039,0.00509386,0.524239 beta-lactamase_39_G281D,beta-lactamase_39_281,TEM-1,beta-lactamase_39,P62593,0.524264,NO,281,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.0495842,0.0406482,0.524264 gb1_A260I,gb1_260,gb1,gb1,P06654,0.524264,NO,260,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.486,-2.952,1.466,,,,,,,0.173,,9.6,HHP,-1.70967,0.177985,0.0055808,0.524264 gb1_G267C,gb1_267,gb1,gb1,P06654,0.524264,NO,267,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.676,-4.642,2.966,,,,,,,1.361,,12.72,AOA,-1.61833,0.177985,0.00264655,0.524264 gb1_N261G,gb1_261,gb1,gb1,P06654,0.524264,NO,261,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-1.863,-2.925,1.062,,,,,,,1.191,,44.87,HPA,-2.16033,0.177985,0.0061875,0.524264 gb1_Y229K,gb1_229,gb1,gb1,P06654,0.524264,NO,229,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-1.282,-3.417,2.135,,,,,,,,,,PHB,-1.4915,0.177985,0.00366605,0.524264 beta-lactamase_2500_A185V,beta-lactamase_2500_185,TEM-1,beta-lactamase_2500,P62593,0.524265,NO,185,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.406,-2.093,0.687,,,H,A,0.46,-1.02,2.999,,65.03,HHP,-1.84033,0.361275,0.00467449,0.524265 kka2_1:2_A78C,kka2_1:2_78,Kka2,kka2_1:2,P00552,0.524395,NO,78,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.744,-4.918,3.174,,0.078,.,B,0.46,-0.53,0.206,,56.06,OHH,-1.863,0.295029,0.00457299,0.524395 beta-lactamase_2500_I54D,beta-lactamase_2500_54,TEM-1,beta-lactamase_2500,P62593,0.524468,NO,54,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-2.838,-3.732,0.894,,0.669,E,B,0.48,-0.14,3.946,,73.78,BHH,-2.337,0.361275,0.00403589,0.524468 kka2_1:1_G55D,kka2_1:1_55,Kka2,kka2_1:1,P00552,0.524518,NO,55,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.625,-2.304,0.679,,0.517,S,b,0.29,1.19,4.035,,63.64,POH,-2.05967,0.520039,0.00667877,0.524518 beta-lactamase_D212Y,beta-lactamase_212,TEM-1,beta-lactamase,P62593,0.524693,NO,212,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.624,-4.398,2.774,4.9705,0.037,,b,1.3,-0.58,12.482,,74.48,HAB,-1.77667,0.221079,0.00644302,0.524693 beta-lactamase_2500_S241Q,beta-lactamase_2500_241,TEM-1,beta-lactamase_2500,P62593,0.524695,NO,241,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.361275,0.00452736,0.524695 Pab1_N127Q,Pab1_127,Pab1,Pab1,P04147,0.524701,NO,127,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-1.079,-3.491,2.412,,0.138,E,B,1.05,-0.51,,,,OPH,-1.13633,0.175299,0.000805159,0.524701 beta-lactamase_L282N,beta-lactamase_282,TEM-1,beta-lactamase,P62593,0.524723,NO,282,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.586,-4.188,2.602,5.16743,0.007,H,A,1.07,0.34,31.31,31.31,63.99,PHH,-1.82367,0.221079,0.0449821,0.524723 kka2_1:1_A56G,kka2_1:1_56,Kka2,kka2_1:1,P00552,0.524736,NO,56,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.083,-2.527,0.444,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.520039,0.00717715,0.524736 beta-lactamase_2500_G234S,beta-lactamase_2500_234,TEM-1,beta-lactamase_2500,P62593,0.524767,NO,234,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.62,-3.161,2.541,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.361275,0.000889577,0.524767 beta-lactamase_625_I140E,beta-lactamase_625_140,TEM-1,beta-lactamase_625,P62593,0.524876,NO,140,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.733,-3.925,2.192,,0.128,H,A,0.48,0.41,1.628,,73.08,PHO,-1.48733,0.213352,0.00597777,0.524876 beta-lactamase_I45R,beta-lactamase_45,TEM-1,beta-lactamase,P62593,0.524877,NO,45,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-2.421,-4.043,1.622,5.31505,,E,B,1,-0.3,2.256,,77.62,HHA,-2.30267,0.221079,0.00452842,0.524877 beta-lactamase_S201P,beta-lactamase_201,TEM-1,beta-lactamase,P62593,0.524889,NO,201,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.183,-3.79,2.607,4.85496,0.064,H,A,0.77,-0.07,4.045,,64.69,HPB,-1.451,0.221079,0.00198815,0.524889 PSD95pdz3_H372V,PSD95pdz3_372,PSD95pdz3,PSD95pdz3,P31016,0.524936,NO,372,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-1.627,-3.435,1.808,5.5607,,,,,17.008,,,,PBA,-1.63033,0.0758425,0.00040301,0.524936 kka2_1:8_E262W,kka2_1:8_262,Kka2,kka2_1:8,P00552,0.524989,NO,262,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-0.829,-5.349,4.52,,0.059,G,A,1.52,-0.18,0.837,,42.42,AAH,-0.816,0.100394,0.0191586,0.524989 kka2_1:8_E262W,kka2_1:8_262,Kka2,kka2_1:8,P00552,0.524989,NO,262,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-0.829,-5.349,4.52,,0.059,G,A,1.52,-0.18,0.837,,42.42,AAH,-0.816,0.100394,0.0191586,0.524989 beta-lactamase_0_T126D,beta-lactamase_0_126,TEM-1,beta-lactamase_0,P62593,0.524999,NO,126,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.122,-2.344,1.222,,0.05,H,A,0.22,-0.05,0.705,,44.41,HPH,-1.60467,0.0500837,0.00244552,0.524999 beta-lactamase_39_T158W,beta-lactamase_39_158,TEM-1,beta-lactamase_39,P62593,0.525156,NO,158,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.116,-5.268,4.152,,0.036,,B,0.22,-0.85,2.755,,69.58,HPB,-1.269,0.0495842,0.00341825,0.525156 kka2_1:2_L232Y,kka2_1:2_232,Kka2,kka2_1:2,P00552,0.525211,NO,232,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.514,-3.053,1.539,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.295029,0.00800103,0.525211 beta-lactamase_W208A,beta-lactamase_208,TEM-1,beta-lactamase,P62593,0.525221,NO,208,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-0.818,-3.528,2.71,5.26277,0.067,H,A,0.99,-0.65,,,,AHH,-1.44133,0.221079,0.00126609,0.525221 kka2_1:1_I254F,kka2_1:1_254,Kka2,kka2_1:1,P00552,0.525415,NO,254,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.933,-3.851,1.918,,0.135,H,A,1.52,-0.6,1.859,,71.59,BHH,-1.668,0.520039,0.0132375,0.525415 beta-lactamase_0_L111N,beta-lactamase_0_111,TEM-1,beta-lactamase_0,P62593,0.525424,NO,111,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.76,-4.132,2.372,,0.328,T,A,0.55,0.93,1.966,,64.34,BHP,-1.884,0.0500837,0.00480671,0.525424 beta-lactamase_W208N,beta-lactamase_208,TEM-1,beta-lactamase,P62593,0.525427,NO,208,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-0.818,-4.348,3.53,5.26277,0.067,H,A,0.99,-0.65,,,,AHH,-1.44133,0.221079,0.00126609,0.525427 beta-lactamase_625_P181I,beta-lactamase_625_181,TEM-1,beta-lactamase_625,P62593,0.525455,NO,181,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.813,-3.974,3.161,,,H,A,0.52,-1.14,1.797,,61.54,HOH,-1.795,0.213352,0.000703122,0.525455 kka2_1:8_G99M,kka2_1:8_99,Kka2,kka2_1:8,P00552,0.525523,NO,99,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.596,-4.958,4.362,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.100394,0.00186055,0.525523 kka2_1:8_G99M,kka2_1:8_99,Kka2,kka2_1:8,P00552,0.525523,NO,99,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.596,-4.958,4.362,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.100394,0.00186055,0.525523 Pab1_L153E,Pab1_153,Pab1,Pab1,P04147,0.525549,NO,153,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.039,-3.707,2.668,,0.46,E,A,,-0.95,,,,HHP,-1.17667,0.175299,0.000321212,0.525549 beta-lactamase_R220N,beta-lactamase_220,TEM-1,beta-lactamase,P62593,0.525632,NO,220,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-0.942,-3.516,2.574,5.65995,0.295,I,A,0.68,-0.76,2.164,,74.48,HBP,-1.33633,0.221079,0.00232421,0.525632 beta-lactamase_0_G76N,beta-lactamase_0_76,TEM-1,beta-lactamase_0,P62593,0.525641,NO,76,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.189,-3.655,2.466,,,H,A,0.29,-0.67,1.188,,67.83,OOH,-1.22267,0.0500837,0.00476637,0.525641 beta-lactamase_39_F149P,beta-lactamase_39_149,TEM-1,beta-lactamase_39,P62593,0.525716,NO,149,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.299,-4.282,2.983,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.0495842,0.00418462,0.525716 kka2_1:2_Q219P,kka2_1:2_219,Kka2,kka2_1:2,P00552,0.525757,NO,219,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-0.93,-3.727,2.797,,0.088,H,A,0.4,-0.85,1.917,,50,HPA,-1.05167,0.295029,0.00237913,0.525757 kka2_1:2_F240H,kka2_1:2_240,Kka2,kka2_1:2,P00552,0.525887,NO,240,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-0.911,-4.571,3.66,,,H,A,0.58,-1.21,0.373,,50.38,BHH,-1.67267,0.295029,0.00552543,0.525887 kka2_1:2_A222G,kka2_1:2_222,Kka2,kka2_1:2,P00552,0.525901,NO,222,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.725,-2.936,2.211,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.295029,0.00207657,0.525901 Pab1_I152P,Pab1_152,Pab1,Pab1,P04147,0.525901,NO,152,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.345,-3.918,2.573,,0.165,E,B,1.23,-0.71,1.288,,71.4,AHH,-1.59433,0.175299,0.000740963,0.525901 beta-lactamase_2500_G142T,beta-lactamase_2500_142,TEM-1,beta-lactamase_2500,P62593,0.525932,NO,142,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.707,-3.568,2.861,,0.034,,p,0.29,-0.64,1.883,,64.69,OOO,-0.834,0.361275,0.00060149,0.525932 kka2_1:8_Y257Q,kka2_1:8_257,Kka2,kka2_1:8,P00552,0.525941,NO,257,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-1.064,-4.113,3.049,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.100394,0.0148191,0.525941 kka2_1:8_Y257Q,kka2_1:8_257,Kka2,kka2_1:8,P00552,0.525941,NO,257,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-1.064,-4.113,3.049,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.100394,0.0148191,0.525941 beta-lactamase_625_Q37P,beta-lactamase_625_37,TEM-1,beta-lactamase_625,P62593,0.525942,NO,37,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.134,-3.965,1.831,,0.613,H,A,0.64,1.98,1.318,,73.08,APH,-2.06967,0.213352,0.00425833,0.525942 kka2_1:1_D250T,kka2_1:1_250,Kka2,kka2_1:1,P00552,0.526057,NO,250,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.015,-3.493,2.478,,0.274,.,b,0.75,-0.46,4.177,,51.89,OAP,-1.83933,0.520039,0.0177103,0.526057 kka2_1:2_L39D,kka2_1:2_39,Kka2,kka2_1:2,P00552,0.526079,NO,39,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.223,-4.127,2.904,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.295029,0.00493618,0.526079 beta-lactamase_0_P250K,beta-lactamase_0_250,TEM-1,beta-lactamase_0,P62593,0.526122,NO,250,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.0500837,0.00550899,0.526122 kka2_1:2_G88L,kka2_1:2_88,Kka2,kka2_1:2,P00552,0.526139,NO,88,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.689,-3.754,2.065,,0.54,S,l,0.75,1.51,2.814,,65.53,HOB,-1.718,0.295029,0.00685559,0.526139 kka2_1:1_G205A,kka2_1:1_205,Kka2,kka2_1:1,P00552,0.526152,NO,205,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.596,-2.881,2.285,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.520039,0.00221855,0.526152 beta-lactamase_0_P181I,beta-lactamase_0_181,TEM-1,beta-lactamase_0,P62593,0.526207,NO,181,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.813,-3.974,3.161,,,H,A,0.52,-1.14,1.357,,61.54,HOH,-1.795,0.0500837,0.000703122,0.526207 kka2_1:8_H135P,kka2_1:8_135,Kka2,kka2_1:8,P00552,0.526219,NO,135,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-1.331,-3.963,2.632,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.100394,0.00532566,0.526219 kka2_1:8_H135P,kka2_1:8_135,Kka2,kka2_1:8,P00552,0.526219,NO,135,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-1.331,-3.963,2.632,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.100394,0.00532566,0.526219 beta-lactamase_0_M115V,beta-lactamase_0_115,TEM-1,beta-lactamase_0,P62593,0.526275,NO,115,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.389,-3.055,1.666,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.0500837,0.0034337,0.526275 beta-lactamase_Y95T,beta-lactamase_95,TEM-1,beta-lactamase,P62593,0.526319,NO,95,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-1.715,-3.697,1.982,5.67068,0.122,,b,0.96,-0.37,2.341,,77.62,BHP,-2.16167,0.221079,0.00479449,0.526319 kka2_1:1_E142A,kka2_1:1_142,Kka2,kka2_1:1,P00552,0.526327,NO,142,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.221,-1.748,-0.473,,0.471,H,A,1.52,0.85,3.626,,65.53,HAB,-2.08033,0.520039,0.00748883,0.526327 beta-lactamase_0_G76R,beta-lactamase_0_76,TEM-1,beta-lactamase_0,P62593,0.526349,NO,76,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.189,-3.905,2.716,,,H,A,0.29,-0.67,1.188,,67.83,OOH,-1.22267,0.0500837,0.00476637,0.526349 kka2_1:1_D101G,kka2_1:1_101,Kka2,kka2_1:1,P00552,0.526417,NO,101,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.028,-3.238,2.21,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.520039,0.00423361,0.526417 PSD95pdz3_G330W,PSD95pdz3_330,PSD95pdz3,PSD95pdz3,P31016,0.526425,NO,330,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.008,-4.779,3.771,4.68351,,,,,31.405,,,,OOA,-1.14,0.0758425,0.000962386,0.526425 kka2_1:4_A237M,kka2_1:4_237,Kka2,kka2_1:4,P00552,0.526518,NO,237,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.12,-4.281,2.161,,0.068,H,A,0.46,-0.71,2.444,,92.05,HHA,-2.10433,0.168804,0.012257,0.526518 beta-lactamase_0_E26D,beta-lactamase_0_26,TEM-1,beta-lactamase_0,P62593,0.526576,NO,26,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.454,-2.507,0.053,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.0500837,0.00297948,0.526576 beta-lactamase_625_L136C,beta-lactamase_625_136,TEM-1,beta-lactamase_625,P62593,0.526666,NO,136,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.232,-4.751,3.519,,,H,A,0.55,-0.34,0.336,,48.95,HHH,-1.088,0.213352,0.00442304,0.526666 kka2_1:8_S32C,kka2_1:8_32,Kka2,kka2_1:8,P00552,0.526774,NO,32,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-0.804,-4.665,3.861,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.100394,0.00149998,0.526774 kka2_1:8_S32C,kka2_1:8_32,Kka2,kka2_1:8,P00552,0.526774,NO,32,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-0.804,-4.665,3.861,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.100394,0.00149998,0.526774 kka2_1:8_S32Y,kka2_1:8_32,Kka2,kka2_1:8,P00552,0.526774,NO,32,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-0.804,-4.191,3.387,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.100394,0.00149998,0.526774 kka2_1:8_S32Y,kka2_1:8_32,Kka2,kka2_1:8,P00552,0.526774,NO,32,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-0.804,-4.191,3.387,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.100394,0.00149998,0.526774 kka2_1:2_D127E,kka2_1:2_127,Kka2,kka2_1:2,P00552,0.526863,NO,127,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.364,-2.659,1.295,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.295029,0.00660501,0.526863 kka2_1:2_Y244C,kka2_1:2_244,Kka2,kka2_1:2,P00552,0.526959,NO,244,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-0.775,-4.89,4.115,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.295029,0.00453187,0.526959 beta-lactamase_T178G,beta-lactamase_178,TEM-1,beta-lactamase,P62593,0.526997,NO,178,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-0.791,-3.358,2.567,5.06452,0.029,E,B,0.3,-1.07,,,,APP,-0.947667,0.221079,0.000684366,0.526997 beta-lactamase_2500_R159C,beta-lactamase_2500_159,TEM-1,beta-lactamase_2500,P62593,0.527028,NO,159,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-0.94,-5.113,4.173,,0.316,,B,1.2,-0.55,2.341,,64.34,PBH,-1.011,0.361275,0.00108472,0.527028 kka2_1:1_P132L,kka2_1:1_132,Kka2,kka2_1:1,P00552,0.527092,NO,132,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.775,-3.61,2.835,,0.692,.,A,0.52,0.56,0.224,,44.7,OOH,-0.825667,0.520039,0.0018489,0.527092 kka2_1:4_L174P,kka2_1:4_174,Kka2,kka2_1:4,P00552,0.527155,NO,174,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.952,-4.115,3.163,,,H,A,0.55,-0.31,1.339,,51.89,BHB,-2.08533,0.168804,0.00438501,0.527155 kka2_1:4_F37S,kka2_1:4_37,Kka2,kka2_1:4,P00552,0.52732,NO,37,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.427,-2.956,1.529,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.168804,0.00586193,0.52732 gb1_K254Q,gb1_254,gb1,gb1,P06654,0.527329,NO,254,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.748,-2.201,0.453,,,,,,,1.793,,37.28,ABH,-2.195,0.177985,0.00622711,0.527329 gb1_V265A,gb1_265,gb1,gb1,P06654,0.527329,NO,265,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.843,-1.912,0.069,,,,,,,0.402,,11.83,OHA,-1.64567,0.177985,0.00360613,0.527329 beta-lactamase_625_T126W,beta-lactamase_625_126,TEM-1,beta-lactamase_625,P62593,0.527362,NO,126,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.122,-5.243,4.121,,0.05,H,A,0.22,-0.05,0.817,,44.41,HPH,-1.60467,0.213352,0.00244552,0.527362 beta-lactamase_A246K,beta-lactamase_246,TEM-1,beta-lactamase,P62593,0.527413,NO,246,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.121,-3.849,1.728,4.78979,0.01,E,B,0.52,-1.01,1.26,,73.78,HHH,-1.55633,0.221079,0.00569458,0.527413 beta-lactamase_F13N,beta-lactamase_13,TEM-1,beta-lactamase,P62593,0.527434,NO,13,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-2.394,-2.68,0.286,,,,,,,4.079,,77.62,OHH,-2.382,0.221079,0.0029078,0.527434 kka2_1:2_G205Q,kka2_1:2_205,Kka2,kka2_1:2,P00552,0.527436,NO,205,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.596,-4.153,3.557,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.295029,0.00221855,0.527436 kka2_1:2_D183P,kka2_1:2_183,Kka2,kka2_1:2,P00552,0.527441,NO,183,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.204,-3.861,2.657,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.295029,0.00426304,0.527441 kka2_1:2_D183T,kka2_1:2_183,Kka2,kka2_1:2,P00552,0.527441,NO,183,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.204,-3.525,2.321,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.295029,0.00426304,0.527441 beta-lactamase_2500_G85W,beta-lactamase_2500_85,TEM-1,beta-lactamase_2500,P62593,0.527443,NO,85,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.011,-5.288,4.277,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.361275,0.00252173,0.527443 PSD95pdz3_A347N,PSD95pdz3_347,PSD95pdz3,PSD95pdz3,P31016,0.527466,NO,347,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.307,-3.58,2.273,4.89689,,,,,15.176,,,,OHA,-1.269,0.0758425,0.00074525,0.527466 beta-lactamase_625_T147P,beta-lactamase_625_147,TEM-1,beta-lactamase_625,P62593,0.527499,NO,147,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.149,-3.818,2.669,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.213352,0.00226017,0.527499 beta-lactamase_39_G43F,beta-lactamase_39_43,TEM-1,beta-lactamase_39,P62593,0.527521,NO,43,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.62,-4.292,3.672,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.0495842,0.00120151,0.527521 kka2_1:2_A71I,kka2_1:2_71,Kka2,kka2_1:2,P00552,0.527704,NO,71,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.824,-4.1,2.276,,0.553,H,A,0.46,0.08,9.788,,64.39,HHP,-1.74033,0.295029,0.00727707,0.527704 beta-lactamase_2500_L248T,beta-lactamase_2500_248,TEM-1,beta-lactamase_2500,P62593,0.527712,NO,248,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.361275,0.00428493,0.527712 beta-lactamase_N168W,beta-lactamase_168,TEM-1,beta-lactamase,P62593,0.527722,NO,168,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-1.029,-5.48,4.451,5.42128,0.113,G,A,0.09,-0.4,1.211,,44.41,HPA,-1.13233,0.221079,0.00288667,0.527722 beta-lactamase_V78E,beta-lactamase_78,TEM-1,beta-lactamase,P62593,0.527783,NO,78,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.459,-3.911,2.452,4.79197,,H,A,0.96,-0.47,1.132,,63.64,HHH,-1.17833,0.221079,0.00492501,0.527783 kka2_1:1_C31V,kka2_1:1_31,Kka2,kka2_1:1,P00552,0.527842,NO,31,C,V,CV,Special,Hydrophobic,5.07,5.60847,0.538465,192,121,117,-4,108.5,140,31.5,-2.246,-2.747,0.501,,1.152,S,b,0.46,4.16,8.272,,63.26,OOP,-1.21533,0.520039,0.00681582,0.527842 kka2_1:2_I228R,kka2_1:2_228,Kka2,kka2_1:2,P00552,0.52791,NO,228,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.142,-4.209,3.067,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.295029,0.00458834,0.52791 beta-lactamase_625_T198W,beta-lactamase_625_198,TEM-1,beta-lactamase_625,P62593,0.527925,NO,198,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.168,-5.419,3.251,,0.489,,B,0.22,-0.13,0.37,,73.78,HPH,-1.98767,0.213352,0.004311,0.527925 kka2_1:1_A78E,kka2_1:1_78,Kka2,kka2_1:1,P00552,0.527929,NO,78,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.744,-3.513,1.769,,0.078,.,B,0.46,-0.53,0.206,,56.06,OHH,-1.863,0.520039,0.00457299,0.527929 beta-lactamase_156_R242W,beta-lactamase_156_242,TEM-1,beta-lactamase_156,P62593,0.527962,NO,242,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.111618,0.00452879,0.527962 kka2_1:1_D261V,kka2_1:1_261,Kka2,kka2_1:1,P00552,0.528044,NO,261,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.708,-3.782,3.074,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.520039,0.0224846,0.528044 kka2_1:8_G30T,kka2_1:8_30,Kka2,kka2_1:8,P00552,0.528161,NO,30,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.596,-3.675,3.079,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.100394,0.00159208,0.528161 kka2_1:8_G30T,kka2_1:8_30,Kka2,kka2_1:8,P00552,0.528161,NO,30,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.596,-3.675,3.079,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.100394,0.00159208,0.528161 beta-lactamase_0_G76H,beta-lactamase_0_76,TEM-1,beta-lactamase_0,P62593,0.528204,NO,76,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.189,-4.754,3.565,,,H,A,0.29,-0.67,1.188,,67.83,OOH,-1.22267,0.0500837,0.00476637,0.528204 kka2_1:1_K175I,kka2_1:1_175,Kka2,kka2_1:1,P00552,0.528318,NO,175,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-2.897,-2.932,0.035,,0.579,H,A,1.3,0.51,9.33,9.33,71.59,HBH,-1.82333,0.520039,0.00693093,0.528318 beta-lactamase_2500_L120I,beta-lactamase_2500_120,TEM-1,beta-lactamase_2500,P62593,0.528342,NO,120,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.044,-2.541,1.497,,,H,A,0.55,-1.13,2.48,,64.69,AHO,-1.13633,0.361275,0.00143563,0.528342 beta-lactamase_2500_N274E,beta-lactamase_2500_274,TEM-1,beta-lactamase_2500,P62593,0.528353,NO,274,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.361275,0.0110418,0.528353 kka2_1:1_V186G,kka2_1:1_186,Kka2,kka2_1:1,P00552,0.528403,NO,186,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.011,-3.743,2.732,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.520039,0.00409703,0.528403 kka2_1:1_I2P,kka2_1:1_2,Kka2,kka2_1:1,P00552,0.528486,NO,2,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.787,-3.734,1.947,,,,,,,2.329,,71.59,HHA,-1.92433,0.520039,0.00246644,0.528486 kka2_1:1_A176H,kka2_1:1_176,Kka2,kka2_1:1,P00552,0.528508,NO,176,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.621,-4.691,3.07,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.520039,0.0083587,0.528508 kka2_1:1_L174V,kka2_1:1_174,Kka2,kka2_1:1,P00552,0.528517,NO,174,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.952,-2.256,1.304,,,H,A,0.55,-0.31,13.276,13.276,51.89,BHB,-2.08533,0.520039,0.00438501,0.528517 beta-lactamase_I283N,beta-lactamase_283,TEM-1,beta-lactamase,P62593,0.528611,NO,283,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.638,-4.102,2.464,5.4178,0.165,H,A,1.23,0.04,1.576,,69.23,HHB,-1.735,0.221079,0.0429138,0.528611 kka2_1:1_L158P,kka2_1:1_158,Kka2,kka2_1:1,P00552,0.528635,NO,158,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.947,-2.892,0.945,,0.095,.,B,0.55,0.77,7.588,,63.64,AHA,-1.25333,0.520039,0.00529068,0.528635 kka2_1:1_Q42L,kka2_1:1_42,Kka2,kka2_1:1,P00552,0.528739,NO,42,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.907,-2.953,0.046,,1.044,T,B,0.4,-0.8,2.792,,71.59,HPO,-2.12433,0.520039,0.00679212,0.528739 beta-lactamase_D174R,beta-lactamase_174,TEM-1,beta-lactamase,P62593,0.52877,NO,174,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.738,-3.933,3.195,5.44133,0.238,,B,1.22,-0.1,,,,PAA,-1.91233,0.221079,0.00125633,0.52877 beta-lactamase_156_R242D,beta-lactamase_156_242,TEM-1,beta-lactamase_156,P62593,0.528775,NO,242,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.111618,0.00452879,0.528775 kka2_1:2_V198E,kka2_1:2_198,Kka2,kka2_1:2,P00552,0.528817,NO,198,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.719,-2.905,1.186,,0.05,E,B,1.48,-0.95,1.074,,56.06,HHA,-1.88667,0.295029,0.00835002,0.528817 beta-lactamase_P181L,beta-lactamase_181,TEM-1,beta-lactamase,P62593,0.528839,NO,181,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.813,-3.546,2.733,5.14752,,H,A,1.1,-1.14,1.357,,61.54,HOH,-1.795,0.221079,0.000703122,0.528839 beta-lactamase_G248S,beta-lactamase_248,TEM-1,beta-lactamase,P62593,0.528918,NO,248,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.794,-2.813,1.019,4.69798,,E,b,0.23,-0.43,1.782,,61.19,HOO,-1.52867,0.221079,0.00428493,0.528918 kka2_1:1_F256S,kka2_1:1_256,Kka2,kka2_1:1,P00552,0.528967,NO,256,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.49,-3.766,2.276,,,H,A,1.62,-0.78,2.354,,53.03,HHH,-1.423,0.520039,0.0132841,0.528967 kka2_1:4_R217C,kka2_1:4_217,Kka2,kka2_1:4,P00552,0.528967,NO,217,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.158,-5.113,3.955,,0.252,T,A,1.2,-0.59,2.074,,52.27,ABH,-1.127,0.168804,0.0047191,0.528967 kka2_1:2_P109D,kka2_1:2_109,Kka2,kka2_1:2,P00552,0.528978,NO,109,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.412,-2.934,1.522,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.295029,0.0070929,0.528978 kka2_1:1_R143D,kka2_1:1_143,Kka2,kka2_1:1,P00552,0.529133,NO,143,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.525,-2.588,0.063,,0.325,H,A,0.16,1.22,3.6,,65.53,ABH,-1.86833,0.520039,0.00662247,0.529133 beta-lactamase_0_H24P,beta-lactamase_0_24,TEM-1,beta-lactamase_0,P62593,0.529205,NO,24,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-2.481,-3.827,1.346,,,,,,,2.708,,93.01,OBO,-2.0035,0.0500837,0.00238894,0.529205 beta-lactamase_39_N130H,beta-lactamase_39_130,TEM-1,beta-lactamase_39,P62593,0.529328,NO,130,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-0.798,-4.005,3.207,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.0495842,0.000683376,0.529328 kka2_1:1_D33E,kka2_1:1_33,Kka2,kka2_1:1,P00552,0.529332,NO,33,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.186,-2.762,0.576,,0.561,S,A,0.75,3.35,2.568,,71.59,PAH,-1.306,0.520039,0.00633568,0.529332 beta-lactamase_2500_T126H,beta-lactamase_2500_126,TEM-1,beta-lactamase_2500,P62593,0.5294,NO,126,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.122,-4.699,3.577,,0.05,H,A,0.22,-0.05,0.817,,44.41,HPH,-1.60467,0.361275,0.00244552,0.5294 kka2_1:4_L60Q,kka2_1:4_60,Kka2,kka2_1:4,P00552,0.529463,NO,60,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.997,-4.233,3.236,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.168804,0.00262176,0.529463 beta-lactamase_D33F,beta-lactamase_33,TEM-1,beta-lactamase,P62593,0.529499,NO,33,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.321,-4.288,1.967,5.05203,0.366,H,A,0.23,0.33,2.032,,77.62,BAH,-2.12133,0.221079,0.00435556,0.529499 beta-lactamase_L205W,beta-lactamase_205,TEM-1,beta-lactamase,P62593,0.529499,NO,205,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.922,-4.959,4.037,5.67023,,H,A,1.3,-0.46,0.678,,42.31,PHH,-1.57767,0.221079,0.00255802,0.529499 beta-lactamase_L219T,beta-lactamase_219,TEM-1,beta-lactamase,P62593,0.529499,NO,219,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.313,-3.55,2.237,5.74153,,I,A,0.84,-0.51,2.321,,74.48,HHB,-1.21533,0.221079,0.00664345,0.529499 beta-lactamase_R59F,beta-lactamase_59,TEM-1,beta-lactamase,P62593,0.529499,NO,59,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.345,-4.379,3.034,5.49837,0.329,S,L,0.68,-0.09,1.806,,73.08,HBO,-2.24267,0.221079,0.00318082,0.529499 beta-lactamase_S201W,beta-lactamase_201,TEM-1,beta-lactamase,P62593,0.529499,NO,201,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.183,-5.344,4.161,4.85496,0.064,H,A,0.77,-0.07,4.045,,64.69,HPB,-1.451,0.221079,0.00198815,0.529499 beta-lactamase_Y44W,beta-lactamase_44,TEM-1,beta-lactamase,P62593,0.529499,NO,44,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-2.547,-5.1,2.553,5.6273,,E,B,2.55,-0.45,2.683,,73.78,OHH,-1.86267,0.221079,0.00426364,0.529499 kka2_1:8_W15D,kka2_1:8_15,Kka2,kka2_1:8,P00552,0.529541,NO,15,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-1.392,-4.212,2.82,,0.01,G,A,1.51,0.15,0.827,,52.27,HHH,-2.10533,0.100394,0.00585505,0.529541 kka2_1:8_W15D,kka2_1:8_15,Kka2,kka2_1:8,P00552,0.529541,NO,15,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-1.392,-4.212,2.82,,0.01,G,A,1.51,0.15,0.827,,52.27,HHH,-2.10533,0.100394,0.00585505,0.529541 kka2_1:8_L170W,kka2_1:8_170,Kka2,kka2_1:8,P00552,0.52961,NO,170,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.28,-5.33,4.05,,0.029,H,A,1.59,0.11,1.453,,62.5,AHH,-1.534,0.100394,0.00730791,0.52961 kka2_1:8_L170W,kka2_1:8_170,Kka2,kka2_1:8,P00552,0.52961,NO,170,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.28,-5.33,4.05,,0.029,H,A,1.59,0.11,1.453,,62.5,AHH,-1.534,0.100394,0.00730791,0.52961 beta-lactamase_625_W288L,beta-lactamase_625_288,TEM-1,beta-lactamase_625,P62593,0.529627,NO,288,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,,,,,,,,,,,,,BHO,,0.213352,,0.529627 kka2_1:1_P194D,kka2_1:1_194,Kka2,kka2_1:1,P00552,0.529657,NO,194,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.846,-2.601,1.755,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.520039,0.00314194,0.529657 beta-lactamase_2500_G265H,beta-lactamase_2500_265,TEM-1,beta-lactamase_2500,P62593,0.529746,NO,265,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.361275,0.00811926,0.529746 beta-lactamase_156_Y95N,beta-lactamase_156_95,TEM-1,beta-lactamase_156,P62593,0.529797,NO,95,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-1.715,-4.149,2.434,,0.122,,b,0.21,-0.37,2.341,,77.62,BHP,-2.16167,0.111618,0.00479449,0.529797 kka2_1:4_E3A,kka2_1:4_3,Kka2,kka2_1:4,P00552,0.529829,NO,3,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.199,-2.95,0.751,,,,,,,7.22,,92.05,HAP,-2.11567,0.168804,0.00267607,0.529829 beta-lactamase_P224I,beta-lactamase_224,TEM-1,beta-lactamase,P62593,0.529847,NO,224,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.893,-4.034,3.141,5.179,0.383,,B,0.99,-0.3,0.383,,74.48,HOH,-1.26433,0.221079,0.00189564,0.529847 kka2_1:4_L212P,kka2_1:4_212,Kka2,kka2_1:4,P00552,0.52985,NO,212,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.904,-4.095,3.191,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.168804,0.0031426,0.52985 kka2_1:2_A144G,kka2_1:2_144,Kka2,kka2_1:2,P00552,0.529886,NO,144,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.859,-3.076,2.217,,,H,A,0.46,0.21,6.844,,52.65,BHB,-1.72933,0.295029,0.00231095,0.529886 beta-lactamase_2500_G226M,beta-lactamase_2500_226,TEM-1,beta-lactamase_2500,P62593,0.529909,NO,226,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.461,-4.924,3.463,,0.701,T,l,0.29,-0.25,5.086,,74.48,HOH,-1.42933,0.361275,0.00665294,0.529909 beta-lactamase_156_G249W,beta-lactamase_156_249,TEM-1,beta-lactamase_156,P62593,0.529919,NO,249,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.111618,0.00220169,0.529919 kka2_1:4_Q219P,kka2_1:4_219,Kka2,kka2_1:4,P00552,0.529989,NO,219,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-0.93,-3.727,2.797,,0.088,H,A,0.64,-0.85,1.537,,50,HPA,-1.05167,0.168804,0.00237913,0.529989 kka2_1:1_D208Y,kka2_1:1_208,Kka2,kka2_1:1,P00552,0.530002,NO,208,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.708,-4.416,3.708,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.520039,0.00212588,0.530002 kka2_1:2_V186R,kka2_1:2_186,Kka2,kka2_1:2,P00552,0.530069,NO,186,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.011,-4.25,3.239,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.295029,0.00409703,0.530069 kka2_1:1_D127Q,kka2_1:1_127,Kka2,kka2_1:1,P00552,0.530081,NO,127,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.364,-3.882,2.518,,0.573,.,B,0.75,0.45,3.414,,50.38,HAO,-1.51067,0.520039,0.00660501,0.530081 beta-lactamase_0_L136H,beta-lactamase_0_136,TEM-1,beta-lactamase_0,P62593,0.530129,NO,136,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.232,-4.999,3.767,,,H,A,0.55,-0.34,0.648,,48.95,HHH,-1.088,0.0500837,0.00442304,0.530129 kka2_1:1_Q100L,kka2_1:1_100,Kka2,kka2_1:1,P00552,0.53018,NO,100,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.77,-2.853,0.083,,0.646,E,B,0.4,-0.79,15.116,15.116,71.59,OPA,-1.46467,0.520039,0.0066405,0.53018 beta-lactamase_D83R,beta-lactamase_83,TEM-1,beta-lactamase,P62593,0.530207,NO,83,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.066,-3.889,2.823,5.40616,0.354,H,A,1.33,0.22,0.861,,48.95,HAH,-1.34733,0.221079,0.00205968,0.530207 beta-lactamase_I275T,beta-lactamase_275,TEM-1,beta-lactamase,P62593,0.530287,NO,275,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.397,-3.543,2.146,5.3999,0.015,H,A,1,-0.52,0.836,,62.59,PHH,-1.541,0.221079,0.0141984,0.530287 Pab1_F129T,Pab1_129,Pab1,Pab1,P04147,0.530319,NO,129,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.269,-3.517,2.248,,0.219,E,B,0.03,-0.07,1.307,,73.83,HHH,-1.27533,0.175299,0.000625182,0.530319 gb1_L233H,gb1_233,gb1,gb1,P06654,0.530337,NO,233,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-2.678,-4.462,1.784,,,,,,,0.822,,45.54,HHP,-2.30267,0.177985,0.00266958,0.530337 gb1_Y271A,gb1_271,gb1,gb1,P06654,0.530337,NO,271,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-1.181,-3.08,1.899,,,,,,,,,,PHA,-1.92933,0.177985,0.00236544,0.530337 beta-lactamase_A185I,beta-lactamase_185,TEM-1,beta-lactamase,P62593,0.530357,NO,185,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.406,-3.361,1.955,4.89877,,H,A,2.34,-1.02,2.999,,65.03,HHP,-1.84033,0.221079,0.00467449,0.530357 kka2_1:2_V214M,kka2_1:2_214,Kka2,kka2_1:2,P00552,0.530361,NO,214,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.261,-4.2,2.939,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.295029,0.00692782,0.530361 beta-lactamase_156_Y44G,beta-lactamase_156_44,TEM-1,beta-lactamase_156,P62593,0.530369,NO,44,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-2.547,-3.687,1.14,,,E,B,0.21,-0.45,2.184,,73.78,OHH,-1.86267,0.111618,0.00426364,0.530369 kka2_1:2_H188C,kka2_1:2_188,Kka2,kka2_1:2,P00552,0.530375,NO,188,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-0.913,-5.139,4.226,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.295029,0.00273139,0.530375 kka2_1:8_A137E,kka2_1:8_137,Kka2,kka2_1:8,P00552,0.530435,NO,137,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.156,-3.863,1.707,,0.029,H,A,1.04,0.34,2.886,,63.26,PHB,-2.559,0.100394,0.00515054,0.530435 kka2_1:8_A137E,kka2_1:8_137,Kka2,kka2_1:8,P00552,0.530435,NO,137,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.156,-3.863,1.707,,0.029,H,A,1.04,0.34,2.886,,63.26,PHB,-2.559,0.100394,0.00515054,0.530435 kka2_1:8_L193W,kka2_1:8_193,Kka2,kka2_1:8,P00552,0.530435,NO,193,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.983,-5.198,4.215,,,G,A,1.59,-1.03,2.234,,65.53,OHO,-0.965333,0.100394,0.00480179,0.530435 kka2_1:8_L193W,kka2_1:8_193,Kka2,kka2_1:8,P00552,0.530435,NO,193,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.983,-5.198,4.215,,,G,A,1.59,-1.03,2.234,,65.53,OHO,-0.965333,0.100394,0.00480179,0.530435 beta-lactamase_625_R202W,beta-lactamase_625_202,TEM-1,beta-lactamase_625,P62593,0.530442,NO,202,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.292,-5.342,4.05,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.213352,0.00321899,0.530442 kka2_1:1_H8F,kka2_1:1_8,Kka2,kka2_1:1,P00552,0.53046,NO,8,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-2.759,-4.004,1.245,,,,,,,16.971,16.971,71.59,HBH,-2.25467,0.520039,0.00256422,0.53046 beta-lactamase_2500_T116K,beta-lactamase_2500_116,TEM-1,beta-lactamase_2500,P62593,0.530523,NO,116,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.28,-3.42,2.14,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.361275,0.00336175,0.530523 kka2_1:1_D134H,kka2_1:1_134,Kka2,kka2_1:1,P00552,0.530576,NO,134,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.969,-4.532,3.563,,0.421,B,B,0.75,0.31,2.329,,49.62,HAB,-1.057,0.520039,0.00270812,0.530576 beta-lactamase_2500_G141H,beta-lactamase_2500_141,TEM-1,beta-lactamase_2500,P62593,0.530608,NO,141,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.828,-4.652,3.824,,0.575,T,l,0.29,-0.28,1.493,,64.69,HOO,-1.08933,0.361275,0.0012419,0.530608 beta-lactamase_A215I,beta-lactamase_215,TEM-1,beta-lactamase,P62593,0.530625,NO,215,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.503,-3.916,2.413,4.82164,,,a,0.75,-0.93,3.583,,74.48,HHO,-1.42633,0.221079,0.00544007,0.530625 beta-lactamase_625_R91C,beta-lactamase_625_91,TEM-1,beta-lactamase_625,P62593,0.530659,NO,91,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.392,-5.127,3.735,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.213352,0.00380226,0.530659 PSD95pdz3_F325N,PSD95pdz3_325,PSD95pdz3,PSD95pdz3,P31016,0.530663,NO,325,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.524,-3.805,2.281,5.50654,,,,,12.7236,,,,OHP,-1.314,0.0758425,0.00102273,0.530663 beta-lactamase_M184T,beta-lactamase_184,TEM-1,beta-lactamase,P62593,0.530752,NO,184,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.593,-2.764,1.171,5.39575,,H,A,1.3,-0.87,2.893,,62.94,HHH,-1.41,0.221079,0.00356019,0.530752 kka2_1:2_D118R,kka2_1:2_118,Kka2,kka2_1:2,P00552,0.530805,NO,118,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.07,-3.951,1.881,,0.61,H,A,0.75,-0.05,2.237,,64.39,HAH,-1.32367,0.295029,0.0067852,0.530805 kka2_1:1_L60V,kka2_1:1_60,Kka2,kka2_1:1,P00552,0.530827,NO,60,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.997,-2.277,1.28,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.520039,0.00262176,0.530827 beta-lactamase_2500_A170Q,beta-lactamase_2500_170,TEM-1,beta-lactamase_2500,P62593,0.530864,NO,170,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.237,-4.086,2.849,,0.126,,L,0.46,-0.35,2.427,,64.69,AHH,-1.63267,0.361275,0.00431903,0.530864 beta-lactamase_2500_D161T,beta-lactamase_2500_161,TEM-1,beta-lactamase_2500,P62593,0.530896,NO,161,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.891,-3.414,2.523,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.361275,0.000897697,0.530896 kka2_1:2_R122N,kka2_1:2_122,Kka2,kka2_1:2,P00552,0.530912,NO,122,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.175,-2.97,0.795,,0.487,H,A,1.2,0.26,16.436,16.436,71.59,BBH,-1.53833,0.295029,0.00736512,0.530912 kka2_1:1_P45N,kka2_1:1_45,Kka2,kka2_1:1,P00552,0.530915,NO,45,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.774,-3.854,2.08,,0.669,.,B,0.52,-0.76,4.882,,71.59,BOH,-2.152,0.520039,0.00590481,0.530915 kka2_1:1_Q26E,kka2_1:1_26,Kka2,kka2_1:1,P00552,0.530922,NO,26,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.18,-2.898,0.718,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.520039,0.00708962,0.530922 kka2_1:2_T85P,kka2_1:2_85,Kka2,kka2_1:2,P00552,0.530933,NO,85,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.165,-4.057,1.892,,0.576,E,B,0.22,1.39,1.853,,71.59,HPA,-2.10133,0.295029,0.00634493,0.530933 kka2_1:1_Q163W,kka2_1:1_163,Kka2,kka2_1:1,P00552,0.530953,NO,163,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.162,-5.401,3.239,,0.58,T,B,0.64,1.85,2.779,,64.02,BPO,-1.78333,0.520039,0.00719507,0.530953 kka2_1:2_L158E,kka2_1:2_158,Kka2,kka2_1:2,P00552,0.530992,NO,158,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.947,-3.926,1.979,,0.095,,B,1.59,0.77,7.588,,63.64,AHA,-1.25333,0.295029,0.00529068,0.530992 kka2_1:1_W15S,kka2_1:1_15,Kka2,kka2_1:1,P00552,0.531169,NO,15,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-1.392,-3.829,2.437,,0.01,G,A,0.47,0.15,20.149,20.149,52.27,HHH,-2.10533,0.520039,0.00585505,0.531169 beta-lactamase_L197W,beta-lactamase_197,TEM-1,beta-lactamase,P62593,0.531184,NO,197,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.853,-5.146,4.293,5.19172,0.007,S,B,1.3,0.33,1.756,,60.14,HHP,-1.833,0.221079,0.00144602,0.531184 beta-lactamase_2500_L191T,beta-lactamase_2500_191,TEM-1,beta-lactamase_2500,P62593,0.531201,NO,191,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.087,-3.447,2.36,,,H,A,0.55,0.09,1.703,,63.29,BHH,-1.445,0.361275,0.00263549,0.531201 beta-lactamase_2500_T263K,beta-lactamase_2500_263,TEM-1,beta-lactamase_2500,P62593,0.531239,NO,263,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.361275,0.0110582,0.531239 kka2_1:8_G210D,kka2_1:8_210,Kka2,kka2_1:8,P00552,0.531327,NO,210,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.095,-3.632,2.537,,0.103,T,A,0.75,-0.62,2.687,,50,OOB,-0.966667,0.100394,0.00598378,0.531327 kka2_1:8_G210D,kka2_1:8_210,Kka2,kka2_1:8,P00552,0.531327,NO,210,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.095,-3.632,2.537,,0.103,T,A,0.75,-0.62,2.687,,50,OOB,-0.966667,0.100394,0.00598378,0.531327 kka2_1:1_R38D,kka2_1:1_38,Kka2,kka2_1:1,P00552,0.53134,NO,38,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.207,-3.931,2.724,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.520039,0.00372499,0.53134 kka2_1:4_R211G,kka2_1:4_211,Kka2,kka2_1:4,P00552,0.53137,NO,211,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-0.899,-3.41,2.511,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.168804,0.00204888,0.53137 beta-lactamase_39_L150K,beta-lactamase_39_150,TEM-1,beta-lactamase_39,P62593,0.531412,NO,150,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.326,-3.711,2.385,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.0495842,0.00463171,0.531412 beta-lactamase_2500_L197V,beta-lactamase_2500_197,TEM-1,beta-lactamase_2500,P62593,0.531447,NO,197,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.853,-2.903,2.05,,0.007,S,B,0.55,0.33,2.421,,60.14,HHP,-1.833,0.361275,0.00144602,0.531447 kka2_1:2_R44V,kka2_1:2_44,Kka2,kka2_1:2,P00552,0.531471,NO,44,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.062,-3.733,1.671,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.295029,0.00745043,0.531471 beta-lactamase_T178Q,beta-lactamase_178,TEM-1,beta-lactamase,P62593,0.531472,NO,178,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-0.791,-3.899,3.108,5.06452,0.029,E,B,0.3,-1.07,,,,APP,-0.947667,0.221079,0.000684366,0.531472 kka2_1:8_R211Y,kka2_1:8_211,Kka2,kka2_1:8,P00552,0.531526,NO,211,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-0.899,-4.076,3.177,,0.12,T,a,0.16,-0.39,0.615,,49.62,OBH,-0.966,0.100394,0.00204888,0.531526 kka2_1:8_R211Y,kka2_1:8_211,Kka2,kka2_1:8,P00552,0.531526,NO,211,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-0.899,-4.076,3.177,,0.12,T,a,0.16,-0.39,0.615,,49.62,OBH,-0.966,0.100394,0.00204888,0.531526 kka2_1:8_C131R,kka2_1:8_131,Kka2,kka2_1:8,P00552,0.531532,NO,131,C,R,CR,Special,PositiveCharge,5.07,6.34148,1.27148,180,121,174,53,108.5,173.4,64.9,-0.831,-4.186,3.355,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.100394,0.00170814,0.531532 kka2_1:8_C131R,kka2_1:8_131,Kka2,kka2_1:8,P00552,0.531532,NO,131,C,R,CR,Special,PositiveCharge,5.07,6.34148,1.27148,180,121,174,53,108.5,173.4,64.9,-0.831,-4.186,3.355,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.100394,0.00170814,0.531532 kka2_1:2_D159L,kka2_1:2_159,Kka2,kka2_1:2,P00552,0.531669,NO,159,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.82,-3.871,3.051,,0.28,.,B,0.75,1.25,0.899,,48.11,HAA,-1.48333,0.295029,0.0030485,0.531669 kka2_1:1_A172T,kka2_1:1_172,Kka2,kka2_1:1,P00552,0.531675,NO,172,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.757,-2.834,1.077,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.520039,0.0079265,0.531675 beta-lactamase_2500_G141R,beta-lactamase_2500_141,TEM-1,beta-lactamase_2500,P62593,0.531687,NO,141,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.828,-3.94,3.112,,0.575,T,l,0.29,-0.28,1.493,,64.69,HOO,-1.08933,0.361275,0.0012419,0.531687 beta-lactamase_2500_R63N,beta-lactamase_2500_63,TEM-1,beta-lactamase_2500,P62593,0.531688,NO,63,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-0.943,-3.531,2.588,,0.218,,B,1.2,-0.31,0.929,,44.06,ABH,-0.992333,0.361275,0.00126938,0.531688 kka2_1:2_V185L,kka2_1:2_185,Kka2,kka2_1:2,P00552,0.531733,NO,185,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.045,-2.834,1.789,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.295029,0.00367031,0.531733 beta-lactamase_A40K,beta-lactamase_40,TEM-1,beta-lactamase,P62593,0.531783,NO,40,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.402,-3.658,2.256,4.9697,0.155,S,B,1.2,0.21,1.714,,73.78,OHB,-1.40267,0.221079,0.00490026,0.531783 beta-lactamase_2500_G52Q,beta-lactamase_2500_52,TEM-1,beta-lactamase_2500,P62593,0.531808,NO,52,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.149,-2.995,1.846,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.361275,0.00340138,0.531808 beta-lactamase_N272I,beta-lactamase_272,TEM-1,beta-lactamase,P62593,0.531826,NO,272,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-1.127,-4.085,2.958,5.37826,0.081,H,A,0.09,-0.97,1.468,,63.64,BPB,-1.56333,0.221079,0.00545371,0.531826 kka2_1:4_E63V,kka2_1:4_63,Kka2,kka2_1:4,P00552,0.531842,NO,63,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-0.762,-3.557,2.795,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.168804,0.00118399,0.531842 kka2_1:8_L126W,kka2_1:8_126,Kka2,kka2_1:8,P00552,0.531874,NO,126,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.246,-5.346,4.1,,0.285,S,B,1.59,0.12,4.443,,51.89,PHA,-1.744,0.100394,0.0066485,0.531874 kka2_1:8_L126W,kka2_1:8_126,Kka2,kka2_1:8,P00552,0.531874,NO,126,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.246,-5.346,4.1,,0.285,S,B,1.59,0.12,4.443,,51.89,PHA,-1.744,0.100394,0.0066485,0.531874 kka2_1:2_K112F,kka2_1:2_112,Kka2,kka2_1:2,P00552,0.531899,NO,112,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-2.491,-4.227,1.736,,0.076,H,A,2.34,-1.37,23.433,23.433,56.06,ABH,-2.00133,0.295029,0.00645389,0.531899 beta-lactamase_2500_R81D,beta-lactamase_2500_81,TEM-1,beta-lactamase_2500,P62593,0.531943,NO,81,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.466,-3.611,2.145,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.361275,0.00499763,0.531943 kka2_1:2_F264S,kka2_1:2_264,Kka2,kka2_1:2,P00552,0.53197,NO,264,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.02,-3.713,2.693,,0.296,.,?,0.58,0.02,2.303,,71.59,HHNA,-0.9655,0.295029,,0.53197 kka2_1:2_A34V,kka2_1:2_34,Kka2,kka2_1:2,P00552,0.532004,NO,34,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.928,-3.231,2.303,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.295029,0.00343484,0.532004 beta-lactamase_2500_I45Q,beta-lactamase_2500_45,TEM-1,beta-lactamase_2500,P62593,0.532042,NO,45,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-2.421,-3.24,0.819,,,E,B,0.48,-0.3,3.793,,77.62,HHA,-2.30267,0.361275,0.00452842,0.532042 kka2_1:1_G21R,kka2_1:1_21,Kka2,kka2_1:1,P00552,0.532042,NO,21,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.368,-3.948,2.58,,0.586,T,l,0.29,-0.75,10.291,10.291,71.59,HOH,-2.10167,0.520039,0.00709648,0.532042 beta-lactamase_2500_L38A,beta-lactamase_2500_38,TEM-1,beta-lactamase_2500,P62593,0.532061,NO,38,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.343,-3.151,1.808,,0.088,H,A,0.55,0.2,2.71,,64.34,PHO,-1.78033,0.361275,0.00373244,0.532061 kka2_1:8_G189T,kka2_1:8_189,Kka2,kka2_1:8,P00552,0.532079,NO,189,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.596,-3.675,3.079,,0.034,S,l,0.75,-0.99,,,,BOA,-0.739,0.100394,0.00253688,0.532079 kka2_1:8_G189T,kka2_1:8_189,Kka2,kka2_1:8,P00552,0.532079,NO,189,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.596,-3.675,3.079,,0.034,S,l,0.75,-0.99,,,,BOA,-0.739,0.100394,0.00253688,0.532079 kka2_1:1_E3W,kka2_1:1_3,Kka2,kka2_1:1,P00552,0.532083,NO,3,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.199,-4.936,2.737,,,,,,,3.435,,92.05,HAP,-2.11567,0.520039,0.00267607,0.532083 beta-lactamase_L218D,beta-lactamase_218,TEM-1,beta-lactamase,P62593,0.532094,NO,218,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.391,-3.905,2.514,4.88972,,I,b,2.89,-0.53,12.788,12.788,74.48,OHH,-1.58867,0.221079,0.00618274,0.532094 PSD95pdz3_F325K,PSD95pdz3_325,PSD95pdz3,PSD95pdz3,P31016,0.532134,NO,325,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.524,-3.589,2.065,5.50654,,,,,12.7236,,,,OHP,-1.314,0.0758425,0.00102273,0.532134 kka2_1:4_F256T,kka2_1:4_256,Kka2,kka2_1:4,P00552,0.532185,NO,256,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.49,-3.783,2.293,,,H,A,0.58,-0.78,1.653,,53.03,HHH,-1.423,0.168804,0.0132841,0.532185 beta-lactamase_R162F,beta-lactamase_162,TEM-1,beta-lactamase,P62593,0.532214,NO,162,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.016,-4.266,3.25,5.34456,0.124,S,B,0.68,-0.37,31.656,31.656,64.69,ABH,-1.25,0.221079,0.000561334,0.532214 Ubiquitin_I61T,Ubiquitin_61,Uba1,Ubiquitin,P0CG48,0.532258,NO,61,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.514,-2.736,1.222,5.19922,0.038,,B,1,-0.76,1.953,,24.53,PHP,-1.70833,0.205827,0.000738268,0.532258 Ubiquitin_K27I,Ubiquitin_27,Uba1,Ubiquitin,P0CG48,0.532258,NO,27,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.064,-4.036,2.972,4.77438,0.086,H,A,2.89,-0.74,2.662,,27.01,HBH,-1.42667,0.205827,0.000767556,0.532258 Ubiquitin_L15W,Ubiquitin_15,Uba1,Ubiquitin,P0CG48,0.532258,NO,15,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.082,-5.194,4.112,5.14718,0.029,E,B,1.16,-0.53,0.936,,38.69,PHA,-1.40833,0.205827,0.000519738,0.532258 Ubiquitin_L56P,Ubiquitin_56,Uba1,Ubiquitin,P0CG48,0.532258,NO,56,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.324,-4.099,2.775,4.83362,,T,A,,-0.91,,,,PHP,-1.60067,0.205827,0.000459465,0.532258 beta-lactamase_156_L136G,beta-lactamase_156_136,TEM-1,beta-lactamase_156,P62593,0.532273,NO,136,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.232,-3.856,2.624,,,H,A,0.55,-0.34,1.04,,48.95,HHH,-1.088,0.111618,0.00442304,0.532273 beta-lactamase_2500_K30C,beta-lactamase_2500_30,TEM-1,beta-lactamase_2500,P62593,0.532288,NO,30,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-2.307,-5.006,2.699,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.361275,0.00448593,0.532288 beta-lactamase_2500_D161V,beta-lactamase_2500_161,TEM-1,beta-lactamase_2500,P62593,0.532413,NO,161,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.891,-3.753,2.862,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.361275,0.000897697,0.532413 beta-lactamase_L205C,beta-lactamase_205,TEM-1,beta-lactamase,P62593,0.532443,NO,205,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.922,-4.692,3.77,5.67023,,H,A,1.3,-0.46,0.678,,42.31,PHH,-1.57767,0.221079,0.00255802,0.532443 kka2_1:1_G245S,kka2_1:1_245,Kka2,kka2_1:1,P00552,0.532485,NO,245,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.812,-3.212,2.4,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.520039,0.00683899,0.532485 beta-lactamase_0_Y95N,beta-lactamase_0_95,TEM-1,beta-lactamase_0,P62593,0.532532,NO,95,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-1.715,-4.149,2.434,,0.122,,b,0.21,-0.37,2.914,,77.62,BHP,-2.16167,0.0500837,0.00479449,0.532532 beta-lactamase_156_S104P,beta-lactamase_156_104,TEM-1,beta-lactamase_156,P62593,0.532559,NO,104,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.015,-3.751,2.736,,0.04,,b,0.27,0.57,4.02,,63.29,HPO,-1.05267,0.111618,0.00218083,0.532559 kka2_1:2_C209S,kka2_1:2_209,Kka2,kka2_1:2,P00552,0.532589,NO,209,C,S,CS,Special,Polar,5.07,5.68,0.61,112,121,105,-16,108.5,89,-19.5,-0.906,-3.458,2.552,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.295029,0.00260862,0.532589 beta-lactamase_T261K,beta-lactamase_261,TEM-1,beta-lactamase,P62593,0.532618,NO,261,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.88,-3.842,0.962,5.65483,0.014,E,B,0.53,-0.39,2.449,,77.62,HPP,-1.771,0.221079,0.0123091,0.532618 kka2_1:8_F263M,kka2_1:8_263,Kka2,kka2_1:8,P00552,0.532693,NO,263,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-0.911,-4.239,3.328,,0.006,G,A,1.62,-0.12,0.928,,45.83,AHH,-0.92,0.100394,0.0172454,0.532693 kka2_1:8_F263M,kka2_1:8_263,Kka2,kka2_1:8,P00552,0.532693,NO,263,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-0.911,-4.239,3.328,,0.006,G,A,1.62,-0.12,0.928,,45.83,AHH,-0.92,0.100394,0.0172454,0.532693 beta-lactamase_P253Y,beta-lactamase_253,TEM-1,beta-lactamase,P62593,0.532757,NO,253,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-2.253,-4.336,2.083,5.24842,0.308,,B,0.73,-0.46,2.293,,73.08,BOP,-2.10633,0.221079,0.00786358,0.532757 beta-lactamase_I244S,beta-lactamase_244,TEM-1,beta-lactamase,P62593,0.532787,NO,244,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.555,-3.602,2.047,5.35885,,E,B,0.01,-0.84,0.379,,77.62,HHH,-1.385,0.221079,0.00605379,0.532787 beta-lactamase_2500_T131V,beta-lactamase_2500_131,TEM-1,beta-lactamase_2500,P62593,0.53283,NO,131,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.328,-3.345,2.017,,,H,A,0.22,-0.69,3.048,,67.48,PPH,-1.00867,0.361275,0.00345886,0.53283 kka2_1:8_A237D,kka2_1:8_237,Kka2,kka2_1:8,P00552,0.53283,NO,237,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.12,-2.999,0.879,,0.068,H,A,0.46,-0.71,0.449,,92.05,HHA,-2.10433,0.100394,0.012257,0.53283 kka2_1:8_A237D,kka2_1:8_237,Kka2,kka2_1:8,P00552,0.53283,NO,237,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.12,-2.999,0.879,,0.068,H,A,0.46,-0.71,0.449,,92.05,HHA,-2.10433,0.100394,0.012257,0.53283 kka2_1:2_Q136E,kka2_1:2_136,Kka2,kka2_1:2,P00552,0.532849,NO,136,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-3.021,-3.472,0.451,,0.331,,b,0.4,0.96,2.726,,92.05,BPH,-2.16933,0.295029,0.00624149,0.532849 beta-lactamase_2500_L100C,beta-lactamase_2500_100,TEM-1,beta-lactamase_2500,P62593,0.532851,NO,100,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.218,-4.758,3.54,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.361275,0.00413885,0.532851 beta-lactamase_156_T178Y,beta-lactamase_156_178,TEM-1,beta-lactamase_156,P62593,0.53288,NO,178,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-0.791,-4.162,3.371,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.111618,0.000684366,0.53288 beta-lactamase_0_I171M,beta-lactamase_0_171,TEM-1,beta-lactamase_0,P62593,0.532899,NO,171,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-2.431,-4.454,2.023,,0.361,,B,0.48,0.53,16.954,16.954,77.62,HHO,-1.55533,0.0500837,0.00623355,0.532899 beta-lactamase_2500_A123T,beta-lactamase_2500_123,TEM-1,beta-lactamase_2500,P62593,0.532939,NO,123,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.834,-3.222,2.388,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.361275,0.0010157,0.532939 beta-lactamase_R241L,beta-lactamase_241,TEM-1,beta-lactamase,P62593,0.532971,NO,241,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.433,-3.342,1.909,5.02621,0.094,E,B,0.68,-0.16,1.327,,50,PBO,-1.42967,0.221079,0.00452736,0.532971 kka2_1:2_L39R,kka2_1:2_39,Kka2,kka2_1:2,P00552,0.533055,NO,39,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.223,-4.155,2.932,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.295029,0.00493618,0.533055 kka2_1:2_D82H,kka2_1:2_82,Kka2,kka2_1:2,P00552,0.533129,NO,82,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.946,-4.75,2.804,,0.341,E,b,0.75,0.52,11.923,11.923,63.64,HAH,-1.98,0.295029,0.00637516,0.533129 beta-lactamase_2500_P165H,beta-lactamase_2500_165,TEM-1,beta-lactamase_2500,P62593,0.533142,NO,165,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.373,-4.751,3.378,,0.203,T,A,0.52,-0.31,0.414,,73.78,AOA,-1.359,0.361275,0.00549538,0.533142 kka2_1:2_P132S,kka2_1:2_132,Kka2,kka2_1:2,P00552,0.533174,NO,132,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.775,-2.585,1.81,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.295029,0.0018489,0.533174 beta-lactamase_2500_R63C,beta-lactamase_2500_63,TEM-1,beta-lactamase_2500,P62593,0.533196,NO,63,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-0.943,-5.05,4.107,,0.218,,B,1.2,-0.31,0.929,,44.06,ABH,-0.992333,0.361275,0.00126938,0.533196 beta-lactamase_2500_Q97C,beta-lactamase_2500_97,TEM-1,beta-lactamase_2500,P62593,0.53328,NO,97,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.072,-5.163,3.091,,0.823,G,A,0.64,2.42,1.157,,77.62,PPP,-2.43833,0.361275,0.0045116,0.53328 beta-lactamase_2500_V42Y,beta-lactamase_2500_42,TEM-1,beta-lactamase_2500,P62593,0.533381,NO,42,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.564,-4.12,2.556,,0.017,E,B,0.44,-0.51,1.86,,63.99,BHO,-1.042,0.361275,0.00404515,0.533381 kka2_1:4_F203V,kka2_1:4_203,Kka2,kka2_1:4,P00552,0.533415,NO,203,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-0.911,-3.287,2.376,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.168804,0.00318738,0.533415 beta-lactamase_2500_R159Y,beta-lactamase_2500_159,TEM-1,beta-lactamase_2500,P62593,0.53342,NO,159,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-0.94,-4.035,3.095,,0.316,,B,1.2,-0.55,2.341,,64.34,PBH,-1.011,0.361275,0.00108472,0.53342 kka2_1:1_A222E,kka2_1:1_222,Kka2,kka2_1:1,P00552,0.533534,NO,222,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.725,-3.468,2.743,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.520039,0.00207657,0.533534 kka2_1:2_D156S,kka2_1:2_156,Kka2,kka2_1:2,P00552,0.533585,NO,156,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.696,-2.049,0.353,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.295029,0.00926998,0.533585 kka2_1:4_L103N,kka2_1:4_103,Kka2,kka2_1:4,P00552,0.533598,NO,103,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-2.362,-3.939,1.577,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.168804,0.00574792,0.533598 beta-lactamase_39_L160R,beta-lactamase_39_160,TEM-1,beta-lactamase_39,P62593,0.533629,NO,160,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.977,-4.03,3.053,,0.022,,B,0.55,-0.6,0.895,,44.41,BHA,-0.936,0.0495842,0.00193775,0.533629 beta-lactamase_N134G,beta-lactamase_134,TEM-1,beta-lactamase,P62593,0.533729,NO,134,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-0.879,-2.976,2.097,5.07245,0.138,H,A,0.09,-0.6,1.441,,53.15,HPH,-1.02233,0.221079,0.000644786,0.533729 kka2_1:4_N200T,kka2_1:4_200,Kka2,kka2_1:4,P00552,0.53375,NO,200,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-2.446,-3.096,0.65,,0.756,T,L,0.61,-0.08,1.746,,64.39,APO,-2.08,0.168804,0.00838549,0.53375 kka2_1:1_E230R,kka2_1:1_230,Kka2,kka2_1:1,P00552,0.533847,NO,230,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.672,-2.504,-0.168,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.520039,0.00920051,0.533847 beta-lactamase_A123M,beta-lactamase_123,TEM-1,beta-lactamase,P62593,0.533942,NO,123,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.834,-4.443,3.609,4.70061,0.039,H,A,0.52,-0.72,0.705,,41.26,PHH,-1.47367,0.221079,0.0010157,0.533942 beta-lactamase_625_L135Y,beta-lactamase_625_135,TEM-1,beta-lactamase_625,P62593,0.533969,NO,135,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.002,-3.991,2.989,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.213352,0.00244423,0.533969 beta-lactamase_625_A40F,beta-lactamase_625_40,TEM-1,beta-lactamase_625,P62593,0.533975,NO,40,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.402,-4.227,2.825,,0.155,S,B,0.46,0.21,1.357,,73.78,OHB,-1.40267,0.213352,0.00490026,0.533975 beta-lactamase_V78S,beta-lactamase_78,TEM-1,beta-lactamase,P62593,0.53401,NO,78,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.459,-3.701,2.242,4.79197,,H,A,0.96,-0.47,1.132,,63.64,HHH,-1.17833,0.221079,0.00492501,0.53401 beta-lactamase_D177C,beta-lactamase_177,TEM-1,beta-lactamase,P62593,0.534037,NO,177,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.967,-5.073,4.106,5.08038,0.006,T,L,1.59,-1.02,3.536,,64.69,BAP,-0.873667,0.221079,0.000864022,0.534037 kka2_1:2_L243Y,kka2_1:2_243,Kka2,kka2_1:2,P00552,0.534103,NO,243,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-2.651,-4.342,1.691,,0.277,H,A,1.59,-0.67,13.165,13.165,92.05,HHH,-2.03767,0.295029,0.00884927,0.534103 kka2_1:2_H124R,kka2_1:2_124,Kka2,kka2_1:2,P00552,0.534221,NO,124,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-0.84,-3.511,2.671,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.295029,0.00211296,0.534221 beta-lactamase_2500_L73H,beta-lactamase_2500_73,TEM-1,beta-lactamase_2500,P62593,0.534263,NO,73,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.507,-4.923,3.416,,,H,A,0.55,-0.64,2.178,,67.83,HHH,-1.487,0.361275,0.00488983,0.534263 beta-lactamase_2500_R59C,beta-lactamase_2500_59,TEM-1,beta-lactamase_2500,P62593,0.534267,NO,59,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.345,-2.854,1.509,,0.329,S,L,1.2,-0.09,3.719,,73.08,HBO,-2.24267,0.361275,0.00318082,0.534267 kka2_1:1_A34T,kka2_1:1_34,Kka2,kka2_1:1,P00552,0.5343,NO,34,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.928,-3.197,2.269,,0.417,.,B,0.46,2.29,0.262,,52.27,AHH,-1.747,0.520039,0.00343484,0.5343 kka2_1:2_A215P,kka2_1:2_215,Kka2,kka2_1:2,P00552,0.534316,NO,215,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.968,-3.768,2.8,,0.039,E,B,0.46,-0.59,2.137,,50.38,HHA,-1.00467,0.295029,0.00529129,0.534316 beta-lactamase_625_Y95G,beta-lactamase_625_95,TEM-1,beta-lactamase_625,P62593,0.534393,NO,95,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-1.715,-3.781,2.066,,0.122,,b,0.21,-0.37,3.355,,77.62,BHP,-2.16167,0.213352,0.00479449,0.534393 kka2_1:1_A56P,kka2_1:1_56,Kka2,kka2_1:1,P00552,0.534454,NO,56,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.083,-1.768,-0.315,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.520039,0.00717715,0.534454 beta-lactamase_2500_R239D,beta-lactamase_2500_239,TEM-1,beta-lactamase_2500,P62593,0.53458,NO,239,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.361275,0.00213852,0.53458 beta-lactamase_L79Q,beta-lactamase_79,TEM-1,beta-lactamase,P62593,0.534619,NO,79,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.842,-4.087,3.245,4.98681,0.007,H,A,1.07,-0.16,0.823,,50.35,HHP,-1.44333,0.221079,0.000947397,0.534619 beta-lactamase_2500_R220L,beta-lactamase_2500_220,TEM-1,beta-lactamase_2500,P62593,0.534624,NO,220,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-0.942,-3.356,2.414,,0.295,I,A,1.2,-0.76,2.175,,74.48,HBP,-1.33633,0.361275,0.00232421,0.534624 beta-lactamase_2500_L47Y,beta-lactamase_2500_47,TEM-1,beta-lactamase_2500,P62593,0.534648,NO,47,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.876,-3.117,1.241,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.361275,0.00439844,0.534648 beta-lactamase_2500_G141S,beta-lactamase_2500_141,TEM-1,beta-lactamase_2500,P62593,0.534682,NO,141,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.828,-3.221,2.393,,0.575,T,l,0.29,-0.28,1.493,,64.69,HOO,-1.08933,0.361275,0.0012419,0.534682 WW_domain_T198M,WW_domain_198,Yap65,WW_domain,P46937,0.534709,NO,198,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.451,-4.249,2.798,5.14348,,,,,,3.158,,70.04,PPH,-1.513,0.153962,0.00224534,0.534709 kka2_1:4_V36R,kka2_1:4_36,Kka2,kka2_1:4,P00552,0.534727,NO,36,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-0.898,-4.231,3.333,,0.292,E,B,0.44,0.21,0.278,,52.27,HHH,-1.484,0.168804,0.00245633,0.534727 beta-lactamase_W227M,beta-lactamase_227,TEM-1,beta-lactamase,P62593,0.534749,NO,227,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-0.982,-4.54,3.558,4.86393,0.272,,B,0.99,-0.29,1.37,,74.48,OHH,-1.595,0.221079,0.00226019,0.534749 kka2_1:1_A222V,kka2_1:1_222,Kka2,kka2_1:1,P00552,0.534773,NO,222,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.725,-3.107,2.382,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.520039,0.00207657,0.534773 kka2_1:2_G189R,kka2_1:2_189,Kka2,kka2_1:2,P00552,0.534887,NO,189,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.596,-3.961,3.365,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.295029,0.00253688,0.534887 kka2_1:1_E111D,kka2_1:1_111,Kka2,kka2_1:1,P00552,0.534896,NO,111,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.28,-2.742,0.462,,0.155,H,A,1.52,-1.14,15.716,15.716,65.53,HAB,-2.27833,0.520039,0.00746789,0.534896 kka2_1:8_R217F,kka2_1:8_217,Kka2,kka2_1:8,P00552,0.534967,NO,217,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.158,-4.264,3.106,,0.252,T,A,0.16,-0.59,1.151,,52.27,ABH,-1.127,0.100394,0.0047191,0.534967 kka2_1:8_R217F,kka2_1:8_217,Kka2,kka2_1:8,P00552,0.534967,NO,217,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.158,-4.264,3.106,,0.252,T,A,0.16,-0.59,1.151,,52.27,ABH,-1.127,0.100394,0.0047191,0.534967 beta-lactamase_S281P,beta-lactamase_281,TEM-1,beta-lactamase,P62593,0.535084,NO,281,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.247,-3.88,1.633,4.73591,0.128,H,A,0.25,-0.26,2.144,,77.62,HPH,-1.847,0.221079,0.0406482,0.535084 beta-lactamase_L219H,beta-lactamase_219,TEM-1,beta-lactamase,P62593,0.535123,NO,219,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.313,-4.957,3.644,5.74153,,I,A,0.84,-0.51,2.321,,74.48,HHB,-1.21533,0.221079,0.00664345,0.535123 beta-lactamase_Y103E,beta-lactamase_103,TEM-1,beta-lactamase,P62593,0.535181,NO,103,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-1.33,-3.564,2.234,5.71734,0.613,S,l,2.55,1.21,5.721,,63.29,AHP,-1.48767,0.221079,0.00443048,0.535181 kka2_1:2_G201M,kka2_1:2_201,Kka2,kka2_1:2,P00552,0.535207,NO,201,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.56,-4.972,3.412,,0.149,T,l,0.29,-0.57,16.092,16.092,52.65,POB,-1.92233,0.295029,0.00820117,0.535207 beta-lactamase_P224F,beta-lactamase_224,TEM-1,beta-lactamase,P62593,0.535237,NO,224,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.893,-4.486,3.593,5.179,0.383,,B,0.99,-0.3,0.383,,74.48,HOH,-1.26433,0.221079,0.00189564,0.535237 kka2_1:4_Q136P,kka2_1:4_136,Kka2,kka2_1:4,P00552,0.535244,NO,136,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-3.021,-2.734,-0.287,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.168804,0.00624149,0.535244 beta-lactamase_T107N,beta-lactamase_107,TEM-1,beta-lactamase,P62593,0.535248,NO,107,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.117,-3.473,2.356,5.23432,,G,A,2.12,-0.06,3.676,,67.83,HPA,-1.265,0.221079,0.00239347,0.535248 beta-lactamase_2500_A40C,beta-lactamase_2500_40,TEM-1,beta-lactamase_2500,P62593,0.535293,NO,40,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.402,-4.779,3.377,,0.155,S,B,0.46,0.21,0.953,,73.78,OHB,-1.40267,0.361275,0.00490026,0.535293 kka2_1:1_Q61D,kka2_1:1_61,Kka2,kka2_1:1,P00552,0.535306,NO,61,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.982,-3.015,0.033,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.520039,0.00612092,0.535306 kka2_1:8_R258W,kka2_1:8_258,Kka2,kka2_1:8,P00552,0.535342,NO,258,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.626,-5.364,3.738,,0.316,H,A,0.16,-0.85,5.58,,53.03,HBH,-1.25933,0.100394,0.00983174,0.535342 kka2_1:8_R258W,kka2_1:8_258,Kka2,kka2_1:8,P00552,0.535342,NO,258,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.626,-5.364,3.738,,0.316,H,A,0.16,-0.85,5.58,,53.03,HBH,-1.25933,0.100394,0.00983174,0.535342 beta-lactamase_2500_S201Q,beta-lactamase_2500_201,TEM-1,beta-lactamase_2500,P62593,0.535417,NO,201,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.183,-2.836,1.653,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.361275,0.00198815,0.535417 beta-lactamase_2500_T116C,beta-lactamase_2500_116,TEM-1,beta-lactamase_2500,P62593,0.535449,NO,116,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.28,-4.831,3.551,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.361275,0.00336175,0.535449 kka2_1:2_H135A,kka2_1:2_135,Kka2,kka2_1:2,P00552,0.535496,NO,135,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-1.331,-2.452,1.121,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.295029,0.00532566,0.535496 beta-lactamase_625_L197E,beta-lactamase_625_197,TEM-1,beta-lactamase_625,P62593,0.535537,NO,197,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.853,-3.853,3,,0.007,S,B,0.55,0.33,1.756,,60.14,HHP,-1.833,0.213352,0.00144602,0.535537 beta-lactamase_2500_K213D,beta-lactamase_2500_213,TEM-1,beta-lactamase_2500,P62593,0.535667,NO,213,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.81,-3.577,1.767,,0.67,,A,2.34,0.29,1.668,,67.83,ABH,-1.57767,0.361275,0.00610411,0.535667 kka2_1:4_G245Q,kka2_1:4_245,Kka2,kka2_1:4,P00552,0.535793,NO,245,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.812,-4.042,3.23,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.168804,0.00683899,0.535793 beta-lactamase_T131P,beta-lactamase_131,TEM-1,beta-lactamase,P62593,0.535805,NO,131,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.328,-3.82,2.492,5.0548,,H,A,0.53,-0.69,3.306,,67.48,PPH,-1.00867,0.221079,0.00345886,0.535805 E1_Ubiquitin_R72N,E1_Ubiquitin_72,Uba1,E1_Ubiquitin,P0CG63,0.535809,NO,72,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.184,-3.265,2.081,,0.077,,B,0.16,-0.1,,,,HBH,-1.08733,0.18783,0.00129853,0.535809 kka2_1:2_E86G,kka2_1:2_86,Kka2,kka2_1:2,P00552,0.535811,NO,86,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.86,-2.302,0.442,,0.369,.,B,1.04,1.92,3.573,,63.26,PAH,-1.98067,0.295029,0.00642858,0.535811 beta-lactamase_T178M,beta-lactamase_178,TEM-1,beta-lactamase,P62593,0.535823,NO,178,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-0.791,-4.48,3.689,5.06452,0.029,E,B,0.3,-1.07,,,,APP,-0.947667,0.221079,0.000684366,0.535823 beta-lactamase_C121T,beta-lactamase_121,TEM-1,beta-lactamase,P62593,0.535873,NO,121,C,T,CT,Special,Polar,5.07,5.6,0.53,149,121,119,-2,108.5,116.1,7.6,-0.953,-3.447,2.494,5.12205,,H,A,2.8,-0.81,7.644,,63.29,HOP,-1.46767,0.221079,0.000744322,0.535873 kka2_1:2_I207T,kka2_1:2_207,Kka2,kka2_1:2,P00552,0.535888,NO,207,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.175,-3.466,2.291,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.295029,0.00611824,0.535888 beta-lactamase_0_D48Q,beta-lactamase_0_48,TEM-1,beta-lactamase_0,P62593,0.535934,NO,48,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.101,-3.681,2.58,,0.189,E,B,0.75,0.21,17.825,17.825,50.35,HAH,-1.62467,0.0500837,0.0027273,0.535934 kka2_1:4_P98F,kka2_1:4_98,Kka2,kka2_1:4,P00552,0.535963,NO,98,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.526,-4.51,2.984,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.168804,0.00622754,0.535963 kka2_1:1_V186T,kka2_1:1_186,Kka2,kka2_1:1,P00552,0.536094,NO,186,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.011,-3.386,2.375,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.520039,0.00409703,0.536094 beta-lactamase_39_G281P,beta-lactamase_39_281,TEM-1,beta-lactamase_39,P62593,0.536096,NO,281,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.0495842,0.0406482,0.536096 kka2_1:1_R258G,kka2_1:1_258,Kka2,kka2_1:1,P00552,0.536152,NO,258,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.626,-3.635,2.009,,0.316,H,A,1.2,-0.85,7.485,7.485,53.03,HBH,-1.25933,0.520039,0.00983174,0.536152 kka2_1:2_C209D,kka2_1:2_209,Kka2,kka2_1:2,P00552,0.536272,NO,209,C,D,CD,Special,negativeCharge,5.07,5.0516,-0.0184,154,121,133,12,108.5,111.1,2.6,-0.906,-3.991,3.085,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.295029,0.00260862,0.536272 beta-lactamase_2500_D212E,beta-lactamase_2500_212,TEM-1,beta-lactamase_2500,P62593,0.536278,NO,212,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.624,-3.306,1.682,,0.037,,b,0.75,-0.58,12.482,,74.48,HAB,-1.77667,0.361275,0.00644302,0.536278 kka2_1:2_A117T,kka2_1:2_117,Kka2,kka2_1:2,P00552,0.536284,NO,117,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.828,-3.259,2.431,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.295029,0.00282984,0.536284 kka2_1:2_E59P,kka2_1:2_59,Kka2,kka2_1:2,P00552,0.536285,NO,59,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-0.952,-3.748,2.796,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.295029,0.00280355,0.536285 kka2_1:2_D183H,kka2_1:2_183,Kka2,kka2_1:2,P00552,0.536399,NO,183,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.204,-4.489,3.285,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.295029,0.00426304,0.536399 kka2_1:8_D190R,kka2_1:8_190,Kka2,kka2_1:8,P00552,0.536407,NO,190,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.708,-3.961,3.253,,0.213,S,b,0.29,-0.82,,,,OAH,-0.711667,0.100394,0.00247989,0.536407 kka2_1:8_D190R,kka2_1:8_190,Kka2,kka2_1:8,P00552,0.536407,NO,190,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.708,-3.961,3.253,,0.213,S,b,0.29,-0.82,,,,OAH,-0.711667,0.100394,0.00247989,0.536407 kka2_1:8_L212Q,kka2_1:8_212,Kka2,kka2_1:8,P00552,0.536423,NO,212,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.904,-4.175,3.271,,,,B,1.59,-0.78,1.708,,42.42,BHO,-0.799667,0.100394,0.0031426,0.536423 kka2_1:8_L212Q,kka2_1:8_212,Kka2,kka2_1:8,P00552,0.536423,NO,212,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.904,-4.175,3.271,,,,B,1.59,-0.78,1.708,,42.42,BHO,-0.799667,0.100394,0.0031426,0.536423 Pab1_K166T,Pab1_166,Pab1,Pab1,P04147,0.536453,NO,166,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.262,-3.314,2.052,,0.299,,l,,0,,,,PBO,-1.21033,0.175299,0.0011038,0.536453 kka2_1:2_W15K,kka2_1:2_15,Kka2,kka2_1:2,P00552,0.536479,NO,15,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-1.392,-3.944,2.552,,0.01,G,A,0.47,0.15,2.586,,52.27,HHH,-2.10533,0.295029,0.00585505,0.536479 beta-lactamase_G279W,beta-lactamase_279,TEM-1,beta-lactamase,P62593,0.53648,NO,279,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.038,-5.237,4.199,4.53882,,H,A,0.46,-0.97,3.066,,62.59,HOH,-1.36467,0.221079,0.0192826,0.53648 kka2_1:2_G30D,kka2_1:2_30,Kka2,kka2_1:2,P00552,0.536553,NO,30,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.596,-3.497,2.901,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.295029,0.00159208,0.536553 beta-lactamase_2500_D212I,beta-lactamase_2500_212,TEM-1,beta-lactamase_2500,P62593,0.536583,NO,212,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.624,-3.045,1.421,,0.037,,b,0.75,-0.58,12.482,,74.48,HAB,-1.77667,0.361275,0.00644302,0.536583 kka2_1:8_D216K,kka2_1:8_216,Kka2,kka2_1:8,P00552,0.536598,NO,216,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.785,-3.508,2.723,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.100394,0.00229969,0.536598 kka2_1:8_D216K,kka2_1:8_216,Kka2,kka2_1:8,P00552,0.536598,NO,216,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.785,-3.508,2.723,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.100394,0.00229969,0.536598 kka2_1:1_M148L,kka2_1:1_148,Kka2,kka2_1:1,P00552,0.536601,NO,148,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.847,-2.054,0.207,,0.268,H,A,1.59,0.71,4.618,,64.39,BHA,-1.65467,0.520039,0.00982664,0.536601 kka2_1:4_E182Y,kka2_1:4_182,Kka2,kka2_1:4,P00552,0.53664,NO,182,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.516,-3.156,1.64,,0.326,.,B,1.04,0.75,4.755,,65.53,OAA,-1.806,0.168804,0.00641548,0.53664 beta-lactamase_2500_P105L,beta-lactamase_2500_105,TEM-1,beta-lactamase_2500,P62593,0.53669,NO,105,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.813,-3.581,2.768,,0.226,T,A,0.52,0.8,3.1,,63.29,POH,-1.01533,0.361275,0.0011981,0.53669 beta-lactamase_2500_T198F,beta-lactamase_2500_198,TEM-1,beta-lactamase_2500,P62593,0.536704,NO,198,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.168,-4.258,2.09,,0.489,,B,0.22,-0.13,0.37,,73.78,HPH,-1.98767,0.361275,0.004311,0.536704 PSD95pdz3_I336F,PSD95pdz3_336,PSD95pdz3,PSD95pdz3,P31016,0.536895,NO,336,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.63,-3.299,1.669,5.11321,,,,,13.6363,,,,OHH,-1.38733,0.0758425,0.000887923,0.536895 kka2_1:2_L103G,kka2_1:2_103,Kka2,kka2_1:2,P00552,0.536945,NO,103,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-2.362,-2.706,0.344,,0.394,T,A,0.55,-0.99,3.499,,63.64,HHP,-1.534,0.295029,0.00574792,0.536945 beta-lactamase_0_P181L,beta-lactamase_0_181,TEM-1,beta-lactamase_0,P62593,0.536957,NO,181,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.813,-3.546,2.733,,,H,A,0.52,-1.14,1.357,,61.54,HOH,-1.795,0.0500837,0.000703122,0.536957 beta-lactamase_2500_R159W,beta-lactamase_2500_159,TEM-1,beta-lactamase_2500,P62593,0.536975,NO,159,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-0.94,-5.32,4.38,,0.316,,B,1.2,-0.55,2.341,,64.34,PBH,-1.011,0.361275,0.00108472,0.536975 beta-lactamase_D83V,beta-lactamase_83,TEM-1,beta-lactamase,P62593,0.537197,NO,83,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.066,-3.762,2.696,5.40616,0.354,H,A,1.33,0.22,0.861,,48.95,HAH,-1.34733,0.221079,0.00205968,0.537197 kka2_1:1_H135Y,kka2_1:1_135,Kka2,kka2_1:1,P00552,0.537206,NO,135,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-1.331,-3.702,2.371,,0.071,.,a,0.17,0.65,3.574,,53.03,ABP,-1.77367,0.520039,0.00532566,0.537206 beta-lactamase_2500_I140S,beta-lactamase_2500_140,TEM-1,beta-lactamase_2500,P62593,0.537221,NO,140,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.733,-3.688,1.955,,0.128,H,A,0.48,0.41,1.628,,73.08,PHO,-1.48733,0.361275,0.00597777,0.537221 kka2_1:1_P128A,kka2_1:1_128,Kka2,kka2_1:1,P00552,0.537351,NO,128,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.922,-2.593,0.671,,0.316,G,A,0.52,0.4,2.178,,56.06,AOH,-1.64733,0.520039,0.00774689,0.537351 kka2_1:8_G210L,kka2_1:8_210,Kka2,kka2_1:8,P00552,0.537366,NO,210,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.095,-3.634,2.539,,0.103,T,A,0.75,-0.62,2.687,,50,OOB,-0.966667,0.100394,0.00598378,0.537366 kka2_1:8_G210L,kka2_1:8_210,Kka2,kka2_1:8,P00552,0.537366,NO,210,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.095,-3.634,2.539,,0.103,T,A,0.75,-0.62,2.687,,50,OOB,-0.966667,0.100394,0.00598378,0.537366 kka2_1:8_K112P,kka2_1:8_112,Kka2,kka2_1:8,P00552,0.537419,NO,112,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-2.491,-4.121,1.63,,0.076,H,A,1.3,-1.37,10.58,10.58,56.06,ABH,-2.00133,0.100394,0.00645389,0.537419 kka2_1:8_K112P,kka2_1:8_112,Kka2,kka2_1:8,P00552,0.537419,NO,112,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-2.491,-4.121,1.63,,0.076,H,A,1.3,-1.37,10.58,10.58,56.06,ABH,-2.00133,0.100394,0.00645389,0.537419 kka2_1:2_E182L,kka2_1:2_182,Kka2,kka2_1:2,P00552,0.537499,NO,182,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.516,-3.646,2.13,,0.326,,B,1.52,0.75,14.547,14.547,65.53,OAA,-1.806,0.295029,0.00641548,0.537499 kka2_1:2_L126G,kka2_1:2_126,Kka2,kka2_1:2,P00552,0.537504,NO,126,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.246,-3.853,2.607,,0.285,S,B,0.55,0.12,1.392,,51.89,PHA,-1.744,0.295029,0.0066485,0.537504 beta-lactamase_2500_A215C,beta-lactamase_2500_215,TEM-1,beta-lactamase_2500,P62593,0.537551,NO,215,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.503,-4.816,3.313,,,,a,0.46,-0.93,3.516,,74.48,HHO,-1.42633,0.361275,0.00544007,0.537551 beta-lactamase_L28I,beta-lactamase_28,TEM-1,beta-lactamase,P62593,0.537644,NO,28,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.579,-2.204,0.625,5.42969,0.277,H,A,0.07,-0.16,19.748,19.748,93.01,PHH,-2.11333,0.221079,0.00359321,0.537644 kka2_1:8_A224P,kka2_1:8_224,Kka2,kka2_1:8,P00552,0.537702,NO,224,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.977,-3.784,2.807,,,H,A,0.46,-1.26,0.357,,63.64,HHP,-1.41033,0.100394,0.00352047,0.537702 kka2_1:8_A224P,kka2_1:8_224,Kka2,kka2_1:8,P00552,0.537702,NO,224,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.977,-3.784,2.807,,,H,A,0.46,-1.26,0.357,,63.64,HHP,-1.41033,0.100394,0.00352047,0.537702 kka2_1:2_Q219I,kka2_1:2_219,Kka2,kka2_1:2,P00552,0.537723,NO,219,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-0.93,-4.062,3.132,,0.088,H,A,0.4,-0.85,1.917,,50,HPA,-1.05167,0.295029,0.00237913,0.537723 beta-lactamase_2500_A235L,beta-lactamase_2500_235,TEM-1,beta-lactamase_2500,P62593,0.537838,NO,235,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.266,-3.325,2.059,,0.32,E,B,0.46,-0.86,0.891,,50,OHO,-0.89,0.361275,0.00493474,0.537838 beta-lactamase_2500_G234C,beta-lactamase_2500_234,TEM-1,beta-lactamase_2500,P62593,0.537845,NO,234,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.62,-5.087,4.467,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.361275,0.000889577,0.537845 kka2_1:8_E111P,kka2_1:8_111,Kka2,kka2_1:8,P00552,0.537919,NO,111,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.28,-4.066,1.786,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.100394,0.00746789,0.537919 kka2_1:8_E111P,kka2_1:8_111,Kka2,kka2_1:8,P00552,0.537919,NO,111,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.28,-4.066,1.786,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.100394,0.00746789,0.537919 kka2_1:2_I141S,kka2_1:2_141,Kka2,kka2_1:2,P00552,0.537926,NO,141,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.495,-3.763,2.268,,0.068,H,A,0.48,-0.01,0.819,,92.05,BHA,-1.689,0.295029,0.00744745,0.537926 beta-lactamase_0_A170N,beta-lactamase_0_170,TEM-1,beta-lactamase_0,P62593,0.537952,NO,170,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.237,-2.833,1.596,,0.126,,L,0.46,-0.35,2.427,,64.69,AHH,-1.63267,0.0500837,0.00431903,0.537952 kka2_1:2_N200R,kka2_1:2_200,Kka2,kka2_1:2,P00552,0.537998,NO,200,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-2.446,-3.001,0.555,,0.756,T,L,0.61,-0.08,2.836,,64.39,APO,-2.08,0.295029,0.00838549,0.537998 kka2_1:2_P128S,kka2_1:2_128,Kka2,kka2_1:2,P00552,0.53805,NO,128,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.922,-3.672,1.75,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.295029,0.00774689,0.53805 beta-lactamase_2500_A230M,beta-lactamase_2500_230,TEM-1,beta-lactamase_2500,P62593,0.538117,NO,230,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.154,-4.69,3.536,,0.01,E,B,0.46,-1.17,1.171,,50,HHA,-1.079,0.361275,0.00516841,0.538117 kka2_1:8_L92W,kka2_1:8_92,Kka2,kka2_1:8,P00552,0.538146,NO,92,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.893,-5.185,4.292,,0.007,E,B,1.59,-0.19,1.719,,63.26,HHH,-0.962,0.100394,0.00307177,0.538146 kka2_1:8_L92W,kka2_1:8_92,Kka2,kka2_1:8,P00552,0.538146,NO,92,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.893,-5.185,4.292,,0.007,E,B,1.59,-0.19,1.719,,63.26,HHH,-0.962,0.100394,0.00307177,0.538146 beta-lactamase_156_D155S,beta-lactamase_156_155,TEM-1,beta-lactamase_156,P62593,0.538169,NO,155,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.889,-3.185,2.296,,0.049,,B,0.75,-0.9,0.315,,64.69,OAB,-1.62267,0.111618,0.00135315,0.538169 kka2_1:8_W91D,kka2_1:8_91,Kka2,kka2_1:8,P00552,0.538169,NO,91,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-1.178,-4.116,2.938,,0.077,E,B,1.51,0.27,2.51,,48.48,AHH,-1.51,0.100394,0.00358653,0.538169 kka2_1:8_W91D,kka2_1:8_91,Kka2,kka2_1:8,P00552,0.538169,NO,91,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-1.178,-4.116,2.938,,0.077,E,B,1.51,0.27,2.51,,48.48,AHH,-1.51,0.100394,0.00358653,0.538169 beta-lactamase_I244F,beta-lactamase_244,TEM-1,beta-lactamase,P62593,0.538234,NO,244,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.555,-3.842,2.287,5.35885,,E,B,0.01,-0.84,0.379,,77.62,HHH,-1.385,0.221079,0.00605379,0.538234 kka2_1:8_Q219F,kka2_1:8_219,Kka2,kka2_1:8,P00552,0.538238,NO,219,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-0.93,-4.344,3.414,,0.088,H,A,0.4,-0.85,0.897,,50,HPA,-1.05167,0.100394,0.00237913,0.538238 kka2_1:8_Q219F,kka2_1:8_219,Kka2,kka2_1:8,P00552,0.538238,NO,219,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-0.93,-4.344,3.414,,0.088,H,A,0.4,-0.85,0.897,,50,HPA,-1.05167,0.100394,0.00237913,0.538238 beta-lactamase_L223W,beta-lactamase_223,TEM-1,beta-lactamase,P62593,0.53824,NO,223,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.055,-5.101,4.046,5.42318,0.27,,B,1.3,0.09,1.511,,74.48,HHO,-1.35033,0.221079,0.00372793,0.53824 beta-lactamase_156_A230T,beta-lactamase_156_230,TEM-1,beta-lactamase_156,P62593,0.538298,NO,230,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.154,-3.381,2.227,,0.01,E,B,0.46,-1.17,2.179,,50,HHA,-1.079,0.111618,0.00516841,0.538298 kka2_1:8_L174R,kka2_1:8_174,Kka2,kka2_1:8,P00552,0.538373,NO,174,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.952,-4.019,3.067,,,H,A,1.59,-0.31,1.204,,51.89,BHB,-2.08533,0.100394,0.00438501,0.538373 kka2_1:8_L174R,kka2_1:8_174,Kka2,kka2_1:8,P00552,0.538373,NO,174,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.952,-4.019,3.067,,,H,A,1.59,-0.31,1.204,,51.89,BHB,-2.08533,0.100394,0.00438501,0.538373 beta-lactamase_G279Y,beta-lactamase_279,TEM-1,beta-lactamase,P62593,0.538384,NO,279,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.038,-4.361,3.323,4.53882,,H,A,0.46,-0.97,3.066,,62.59,HOH,-1.36467,0.221079,0.0192826,0.538384 kka2_1:4_L241T,kka2_1:4_241,Kka2,kka2_1:4,P00552,0.538404,NO,241,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.158,-3.592,2.434,,0.08,H,A,0.55,-0.82,1.598,,63.26,HHH,-1.58533,0.168804,0.0117299,0.538404 kka2_1:1_C209G,kka2_1:1_209,Kka2,kka2_1:1,P00552,0.538407,NO,209,C,G,CG,Special,Special,5.07,3.29388,-1.77612,159,121,75,-46,108.5,60.1,-48.4,-0.906,-3.655,2.749,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.520039,0.00260862,0.538407 kka2_1:2_L170V,kka2_1:2_170,Kka2,kka2_1:2,P00552,0.538439,NO,170,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.28,-1.716,0.436,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.295029,0.00730791,0.538439 beta-lactamase_2500_A133D,beta-lactamase_2500_133,TEM-1,beta-lactamase_2500,P62593,0.538546,NO,133,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.186,-3.675,2.489,,,H,A,0.46,-0.86,2.649,,67.83,HHP,-0.988333,0.361275,0.00468022,0.538546 beta-lactamase_P20Y,beta-lactamase_20,TEM-1,beta-lactamase,P62593,0.538549,NO,20,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.74,-4.252,2.512,,,,,,,0.368,,67.83,HOH,-1.765,0.221079,0.00235322,0.538549 beta-lactamase_625_G114Q,beta-lactamase_625_114,TEM-1,beta-lactamase_625,P62593,0.53862,NO,114,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.094,-4.039,2.945,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.213352,0.00224919,0.53862 beta-lactamase_2500_G154R,beta-lactamase_2500_154,TEM-1,beta-lactamase_2500,P62593,0.538655,NO,154,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.823,-3.969,3.146,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.361275,0.00180205,0.538655 beta-lactamase_D231R,beta-lactamase_231,TEM-1,beta-lactamase,P62593,0.538697,NO,231,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.816,-3.896,3.08,5.06651,,E,B,1.22,-1.06,0.319,,65.38,HAB,-0.994,0.221079,0.00107395,0.538697 kka2_1:8_G233R,kka2_1:8_233,Kka2,kka2_1:8,P00552,0.538708,NO,233,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.748,-4.006,3.258,,0.172,,b,0.75,-0.27,1.134,,49.24,HOO,-1.72067,0.100394,0.00232366,0.538708 kka2_1:8_G233R,kka2_1:8_233,Kka2,kka2_1:8,P00552,0.538708,NO,233,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.748,-4.006,3.258,,0.172,,b,0.75,-0.27,1.134,,49.24,HOO,-1.72067,0.100394,0.00232366,0.538708 kka2_1:8_I196W,kka2_1:8_196,Kka2,kka2_1:8,P00552,0.538711,NO,196,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-2.115,-4.933,2.818,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.100394,0.0107273,0.538711 kka2_1:8_I196W,kka2_1:8_196,Kka2,kka2_1:8,P00552,0.538711,NO,196,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-2.115,-4.933,2.818,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.100394,0.0107273,0.538711 beta-lactamase_A34H,beta-lactamase_34,TEM-1,beta-lactamase,P62593,0.538744,NO,34,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.059,-4.883,2.824,4.9129,,H,A,0.75,-0.54,3.614,,73.78,AHA,-1.74967,0.221079,0.00407913,0.538744 kka2_1:1_D180H,kka2_1:1_180,Kka2,kka2_1:1,P00552,0.538755,NO,180,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.416,-3.405,0.989,,1.03,S,a,0.75,1.5,1.534,,71.59,OAO,-2.02933,0.520039,0.00756412,0.538755 kka2_1:2_I196T,kka2_1:2_196,Kka2,kka2_1:2,P00552,0.538778,NO,196,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-2.115,-3.682,1.567,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.295029,0.0107273,0.538778 beta-lactamase_2500_E87W,beta-lactamase_2500_87,TEM-1,beta-lactamase_2500,P62593,0.538779,NO,87,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.421,-5.437,4.016,,0.048,,B,1.04,0.92,17.923,17.923,64.69,PAP,-1.969,0.361275,0.00337888,0.538779 beta-lactamase_625_R220S,beta-lactamase_625_220,TEM-1,beta-lactamase_625,P62593,0.538857,NO,220,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-0.942,-3.349,2.407,,0.295,I,A,1.2,-0.76,5.086,,74.48,HBP,-1.33633,0.213352,0.00232421,0.538857 beta-lactamase_P143K,beta-lactamase_143,TEM-1,beta-lactamase,P62593,0.538857,NO,143,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.967,-3.581,2.614,5.16366,0.075,H,A,0.99,-0.37,0.479,,66.78,OOB,-1.354,0.221079,0.00114551,0.538857 beta-lactamase_2500_A123G,beta-lactamase_2500_123,TEM-1,beta-lactamase_2500,P62593,0.538919,NO,123,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.834,-2.991,2.157,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.361275,0.0010157,0.538919 beta-lactamase_39_A133H,beta-lactamase_39_133,TEM-1,beta-lactamase_39,P62593,0.538923,NO,133,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.186,-4.769,3.583,,,H,A,0.46,-0.86,0.373,,67.83,HHP,-0.988333,0.0495842,0.00468022,0.538923 kka2_1:4_L93R,kka2_1:4_93,Kka2,kka2_1:4,P00552,0.53899,NO,93,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.815,-2.776,1.961,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.168804,0.00131498,0.53899 beta-lactamase_2500_Y103T,beta-lactamase_2500_103,TEM-1,beta-lactamase_2500,P62593,0.539036,NO,103,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-1.33,-3.696,2.366,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.361275,0.00443048,0.539036 gb1_N263F,gb1_263,gb1,gb1,P06654,0.539037,NO,263,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-1.162,-4.069,2.907,,,,,,,,,,APO,-2.04233,0.177985,0.0035297,0.539037 kka2_1:2_P167H,kka2_1:2_167,Kka2,kka2_1:2,P00552,0.539087,NO,167,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-2.403,-4.915,2.512,,0.18,H,A,0.52,0.75,3.6,,64.39,HOH,-2.26633,0.295029,0.00543203,0.539087 kka2_1:4_H188C,kka2_1:4_188,Kka2,kka2_1:4,P00552,0.539121,NO,188,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-0.913,-5.139,4.226,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.168804,0.00273139,0.539121 kka2_1:1_I207Q,kka2_1:1_207,Kka2,kka2_1:1,P00552,0.539137,NO,207,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.175,-4.367,3.192,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.520039,0.00611824,0.539137 beta-lactamase_625_E56F,beta-lactamase_625_56,TEM-1,beta-lactamase_625,P62593,0.539157,NO,56,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.043,-4.191,2.148,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.213352,0.00238534,0.539157 kka2_1:1_G95S,kka2_1:1_95,Kka2,kka2_1:1,P00552,0.539167,NO,95,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-2.403,-1.66,-0.743,,0.126,E,B,0.29,-0.74,7.822,,71.59,HOA,-2.198,0.520039,0.00743616,0.539167 beta-lactamase_39_L120E,beta-lactamase_39_120,TEM-1,beta-lactamase_39,P62593,0.539177,NO,120,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.044,-3.83,2.786,,,H,A,0.55,-1.13,22.254,22.254,64.69,AHO,-1.13633,0.0495842,0.00143563,0.539177 kka2_1:4_N200Y,kka2_1:4_200,Kka2,kka2_1:4,P00552,0.539201,NO,200,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-2.446,-4.44,1.994,,0.756,T,L,0.61,-0.08,1.746,,64.39,APO,-2.08,0.168804,0.00838549,0.539201 beta-lactamase_0_A211Q,beta-lactamase_0_211,TEM-1,beta-lactamase_0,P62593,0.539218,NO,211,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.896,-3.096,1.2,,0.369,T,A,0.46,-0.69,8.527,8.527,77.62,AHA,-1.94633,0.0500837,0.00648183,0.539218 kka2_1:8_F240H,kka2_1:8_240,Kka2,kka2_1:8,P00552,0.539253,NO,240,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-0.911,-4.571,3.66,,,H,A,1.62,-1.21,0.697,,50.38,BHH,-1.67267,0.100394,0.00552543,0.539253 kka2_1:8_F240H,kka2_1:8_240,Kka2,kka2_1:8,P00552,0.539253,NO,240,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-0.911,-4.571,3.66,,,H,A,1.62,-1.21,0.697,,50.38,BHH,-1.67267,0.100394,0.00552543,0.539253 Pab1_K131N,Pab1_131,Pab1,Pab1,P04147,0.539256,NO,131,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.083,-3.265,2.182,,0.462,E,B,1.82,0.57,,,,HBP,-1.12467,0.175299,0.000349395,0.539256 beta-lactamase_156_L146N,beta-lactamase_156_146,TEM-1,beta-lactamase_156,P62593,0.53931,NO,146,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.462,-4.208,2.746,,0.007,H,A,0.55,-0.56,1.578,,64.69,AHP,-1.656,0.111618,0.00474542,0.53931 beta-lactamase_2500_L192A,beta-lactamase_2500_192,TEM-1,beta-lactamase_2500,P62593,0.539331,NO,192,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.254,-2.317,1.063,,0.095,H,A,0.55,0.35,1.902,,60.14,HHP,-1.41833,0.361275,0.00558728,0.539331 kka2_1:2_M197D,kka2_1:2_197,Kka2,kka2_1:2,P00552,0.539361,NO,197,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.707,-4.104,2.397,,0.121,E,B,0.55,-1.19,2.097,,65.53,HHH,-1.847,0.295029,0.00921295,0.539361 kka2_1:1_T28Q,kka2_1:1_28,Kka2,kka2_1:1,P00552,0.539363,NO,28,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.883,-4.073,2.19,,0.353,S,B,0.22,2.02,1.12,,63.64,PPH,-1.74467,0.520039,0.00743084,0.539363 beta-lactamase_2500_M67H,beta-lactamase_2500_67,TEM-1,beta-lactamase_2500,P62593,0.539365,NO,67,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-2.231,-4.763,2.532,,0.006,G,P,0.55,-0.81,2.653,,65.03,HHP,-1.502,0.361275,0.00409753,0.539365 beta-lactamase_2500_A215P,beta-lactamase_2500_215,TEM-1,beta-lactamase_2500,P62593,0.539396,NO,215,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.503,-3.85,2.347,,,,a,0.46,-0.93,3.516,,74.48,HHO,-1.42633,0.361275,0.00544007,0.539396 beta-lactamase_2500_P165D,beta-lactamase_2500_165,TEM-1,beta-lactamase_2500,P62593,0.539464,NO,165,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.373,-3.54,2.167,,0.203,T,A,0.52,-0.31,0.414,,73.78,AOA,-1.359,0.361275,0.00549538,0.539464 beta-lactamase_2500_L191Y,beta-lactamase_2500_191,TEM-1,beta-lactamase_2500,P62593,0.539512,NO,191,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.087,-3.913,2.826,,,H,A,0.55,0.09,1.703,,63.29,BHH,-1.445,0.361275,0.00263549,0.539512 kka2_1:1_A168Y,kka2_1:1_168,Kka2,kka2_1:1,P00552,0.539523,NO,168,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.989,-4.327,2.338,,0.67,H,A,0.46,0.15,25.546,25.546,64.39,OHA,-2.12933,0.520039,0.00806773,0.539523 beta-lactamase_2500_A185C,beta-lactamase_2500_185,TEM-1,beta-lactamase_2500,P62593,0.539625,NO,185,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.406,-4.699,3.293,,,H,A,0.46,-1.02,2.999,,65.03,HHP,-1.84033,0.361275,0.00467449,0.539625 kka2_1:8_L232R,kka2_1:8_232,Kka2,kka2_1:8,P00552,0.539644,NO,232,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.514,-4.216,2.702,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.100394,0.00800103,0.539644 kka2_1:8_L232R,kka2_1:8_232,Kka2,kka2_1:8,P00552,0.539644,NO,232,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.514,-4.216,2.702,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.100394,0.00800103,0.539644 kka2_1:1_A247G,kka2_1:1_247,Kka2,kka2_1:1,P00552,0.539671,NO,247,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.459,-2.518,0.059,,1.01,S,A,0.46,0.65,7.731,7.731,92.05,HHH,-2.197,0.520039,0.0102428,0.539671 beta-lactamase_2500_E56C,beta-lactamase_2500_56,TEM-1,beta-lactamase_2500,P62593,0.539678,NO,56,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.043,-4.827,2.784,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.361275,0.00238534,0.539678 kka2_1:1_A222D,kka2_1:1_222,Kka2,kka2_1:1,P00552,0.5397,NO,222,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.725,-3.722,2.997,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.520039,0.00207657,0.5397 beta-lactamase_2500_G52S,beta-lactamase_2500_52,TEM-1,beta-lactamase_2500,P62593,0.539718,NO,52,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.149,-2.647,1.498,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.361275,0.00340138,0.539718 beta-lactamase_2500_R257V,beta-lactamase_2500_257,TEM-1,beta-lactamase_2500,P62593,0.539726,NO,257,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.533,-4.11,2.577,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.361275,0.00756629,0.539726 kka2_1:2_D62A,kka2_1:2_62,Kka2,kka2_1:2,P00552,0.539856,NO,62,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.591,-2.125,0.534,,0.262,H,A,0.75,0.08,10.048,10.048,64.39,PAA,-1.77833,0.295029,0.00744243,0.539856 WW_domain_T198P,WW_domain_198,Yap65,WW_domain,P46937,0.539887,NO,198,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.451,-3.627,2.176,5.14348,,,,,,3.158,,70.04,PPH,-1.513,0.153962,0.00224534,0.539887 kka2_1:2_M148F,kka2_1:2_148,Kka2,kka2_1:2,P00552,0.539968,NO,148,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.847,-4.011,2.164,,0.268,H,A,1.59,0.71,1.439,,64.39,BHA,-1.65467,0.295029,0.00982664,0.539968 kka2_1:8_W69T,kka2_1:8_69,Kka2,kka2_1:8,P00552,0.540013,NO,69,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-0.859,-3.698,2.839,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.100394,0.0012874,0.540013 kka2_1:8_W69T,kka2_1:8_69,Kka2,kka2_1:8,P00552,0.540013,NO,69,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-0.859,-3.698,2.839,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.100394,0.0012874,0.540013 kka2_1:2_L152E,kka2_1:2_152,Kka2,kka2_1:2,P00552,0.540016,NO,152,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.521,-3.005,1.484,,0.547,.,A,0.55,1.36,4.526,,63.64,OHH,-1.162,0.295029,0.00674868,0.540016 beta-lactamase_2500_R92D,beta-lactamase_2500_92,TEM-1,beta-lactamase_2500,P62593,0.54006,NO,92,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.718,-3.708,1.99,,0.479,E,B,1.2,1.36,3.069,,65.38,BBH,-1.50367,0.361275,0.00429626,0.54006 kka2_1:2_D101G,kka2_1:2_101,Kka2,kka2_1:2,P00552,0.540091,NO,101,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.028,-3.238,2.21,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.295029,0.00423361,0.540091 beta-lactamase_156_T131R,beta-lactamase_156_131,TEM-1,beta-lactamase_156,P62593,0.540093,NO,131,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.328,-2.888,1.56,,,H,A,0.22,-0.69,2.031,,67.48,PPH,-1.00867,0.111618,0.00345886,0.540093 beta-lactamase_2500_G216V,beta-lactamase_2500_216,TEM-1,beta-lactamase_2500,P62593,0.540119,NO,216,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.477,-3.793,2.316,,0.437,I,A,0.29,-0.58,1.983,,74.48,HOO,-1.68067,0.361275,0.00639568,0.540119 beta-lactamase_W208C,beta-lactamase_208,TEM-1,beta-lactamase,P62593,0.540122,NO,208,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-0.818,-4.862,4.044,5.26277,0.067,H,A,0.99,-0.65,,,,AHH,-1.44133,0.221079,0.00126609,0.540122 kka2_1:8_L170H,kka2_1:8_170,Kka2,kka2_1:8,P00552,0.540241,NO,170,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.28,-5.007,3.727,,0.029,H,A,1.59,0.11,1.453,,62.5,AHH,-1.534,0.100394,0.00730791,0.540241 kka2_1:8_L170H,kka2_1:8_170,Kka2,kka2_1:8,P00552,0.540241,NO,170,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.28,-5.007,3.727,,0.029,H,A,1.59,0.11,1.453,,62.5,AHH,-1.534,0.100394,0.00730791,0.540241 beta-lactamase_2500_V31M,beta-lactamase_2500_31,TEM-1,beta-lactamase_2500,P62593,0.540304,NO,31,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.822,-3.184,1.362,,,H,A,0.44,-0.46,0.955,,73.78,BHB,-2.03767,0.361275,0.00478065,0.540304 kka2_1:1_W91Q,kka2_1:1_91,Kka2,kka2_1:1,P00552,0.54031,NO,91,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-1.178,-4.104,2.926,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.520039,0.00358653,0.54031 beta-lactamase_39_L284P,beta-lactamase_39_284,TEM-1,beta-lactamase_39,P62593,0.540311,NO,284,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.0495842,0.0686156,0.540311 Ubiquitin_T12P,Ubiquitin_12,Uba1,Ubiquitin,P0CG48,0.540323,NO,12,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.288,-3.774,2.486,4.93973,0.417,E,B,0.8,0.12,2.762,,25.84,BPH,-1.39867,0.205827,0.000657544,0.540323 beta-lactamase_2500_R162K,beta-lactamase_2500_162,TEM-1,beta-lactamase_2500,P62593,0.540326,NO,162,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.016,-2.948,1.932,,0.124,S,B,1.2,-0.37,6.199,,64.69,ABH,-1.25,0.361275,0.000561334,0.540326 kka2_1:2_R89N,kka2_1:2_89,Kka2,kka2_1:2,P00552,0.540332,NO,89,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.548,-3.002,1.454,,0.209,E,B,1.2,1.41,14.396,14.396,64.39,OBA,-1.89867,0.295029,0.00524373,0.540332 beta-lactamase_2500_R63A,beta-lactamase_2500_63,TEM-1,beta-lactamase_2500,P62593,0.540384,NO,63,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-0.943,-3.103,2.16,,0.218,,B,1.2,-0.31,0.929,,44.06,ABH,-0.992333,0.361275,0.00126938,0.540384 WW_domain_L173T,WW_domain_173,Yap65,WW_domain,P46937,0.540447,NO,173,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.117,-3.198,2.081,,,,,,,,,,OHO,-1.06233,0.153962,0.000851849,0.540447 kka2_1:1_I254M,kka2_1:1_254,Kka2,kka2_1:1,P00552,0.540456,NO,254,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.933,-2.224,0.291,,0.135,H,A,1.52,-0.6,1.859,,71.59,BHH,-1.668,0.520039,0.0132375,0.540456 kka2_1:4_L193R,kka2_1:4_193,Kka2,kka2_1:4,P00552,0.540495,NO,193,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.983,-3.937,2.954,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.168804,0.00480179,0.540495 PSD95pdz3_I341S,PSD95pdz3_341,PSD95pdz3,PSD95pdz3,P31016,0.540521,NO,341,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.63,-3.292,1.662,5.73946,,,,,10.3187,,,,HHH,-1.50033,0.0758425,0.000824087,0.540521 beta-lactamase_625_I245F,beta-lactamase_625_245,TEM-1,beta-lactamase_625,P62593,0.540528,NO,245,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.213352,0.00391032,0.540528 kka2_1:2_V49T,kka2_1:2_49,Kka2,kka2_1:2,P00552,0.540535,NO,49,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.614,-3.462,1.848,,,E,B,0.44,-0.77,1.233,,64.39,HHB,-1.3,0.295029,0.00615685,0.540535 beta-lactamase_2500_L150Q,beta-lactamase_2500_150,TEM-1,beta-lactamase_2500,P62593,0.540579,NO,150,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.326,-4.106,2.78,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.361275,0.00463171,0.540579 kka2_1:8_D159F,kka2_1:8_159,Kka2,kka2_1:8,P00552,0.540645,NO,159,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.82,-4.355,3.535,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.100394,0.0030485,0.540645 kka2_1:8_D159F,kka2_1:8_159,Kka2,kka2_1:8,P00552,0.540645,NO,159,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.82,-4.355,3.535,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.100394,0.0030485,0.540645 kka2_1:1_Q42S,kka2_1:1_42,Kka2,kka2_1:1,P00552,0.540653,NO,42,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.907,-2.69,-0.217,,1.044,T,B,0.4,-0.8,2.792,,71.59,HPO,-2.12433,0.520039,0.00679212,0.540653 beta-lactamase_A123H,beta-lactamase_123,TEM-1,beta-lactamase,P62593,0.540776,NO,123,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.834,-4.729,3.895,4.70061,0.039,H,A,0.52,-0.72,0.705,,41.26,PHH,-1.47367,0.221079,0.0010157,0.540776 beta-lactamase_G114P,beta-lactamase_114,TEM-1,beta-lactamase,P62593,0.540776,NO,114,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.094,-3.918,2.824,4.92659,0.011,,p,0.77,0.35,2.148,,41.61,AOH,-1.43733,0.221079,0.00224919,0.540776 kka2_1:2_P167K,kka2_1:2_167,Kka2,kka2_1:2,P00552,0.540815,NO,167,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-2.403,-3.717,1.314,,0.18,H,A,0.52,0.75,3.6,,64.39,HOH,-2.26633,0.295029,0.00543203,0.540815 kka2_1:2_A229N,kka2_1:2_229,Kka2,kka2_1:2,P00552,0.540861,NO,229,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.739,-3.848,2.109,,0.32,H,A,0.46,-0.7,6.549,,63.64,HHA,-1.851,0.295029,0.00942138,0.540861 beta-lactamase_2500_Y103V,beta-lactamase_2500_103,TEM-1,beta-lactamase_2500,P62593,0.540881,NO,103,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-1.33,-3.602,2.272,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.361275,0.00443048,0.540881 beta-lactamase_2500_H110T,beta-lactamase_2500_110,TEM-1,beta-lactamase_2500,P62593,0.540898,NO,110,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-1.706,-3.697,1.991,,0.341,G,a,0.17,1.08,31.31,31.31,64.69,BBH,-1.73333,0.361275,0.00441499,0.540898 beta-lactamase_0_L146M,beta-lactamase_0_146,TEM-1,beta-lactamase_0,P62593,0.54091,NO,146,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.462,-4.183,2.721,,0.007,H,A,0.55,-0.56,2.051,,64.69,AHP,-1.656,0.0500837,0.00474542,0.54091 kka2_1:1_W69D,kka2_1:1_69,Kka2,kka2_1:1,P00552,0.540923,NO,69,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-0.859,-4.17,3.311,,0.164,H,A,0.47,0.15,5.074,,38.64,PHH,-1.49967,0.520039,0.0012874,0.540923 beta-lactamase_2500_A215H,beta-lactamase_2500_215,TEM-1,beta-lactamase_2500,P62593,0.54106,NO,215,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.503,-4.741,3.238,,,,a,0.46,-0.93,3.516,,74.48,HHO,-1.42633,0.361275,0.00544007,0.54106 beta-lactamase_2500_Y103A,beta-lactamase_2500_103,TEM-1,beta-lactamase_2500,P62593,0.541078,NO,103,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-1.33,-3.426,2.096,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.361275,0.00443048,0.541078 kka2_1:8_F171G,kka2_1:8_171,Kka2,kka2_1:8,P00552,0.541079,NO,171,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.326,-3.793,2.467,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.100394,0.00821426,0.541079 kka2_1:8_F171G,kka2_1:8_171,Kka2,kka2_1:8,P00552,0.541079,NO,171,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.326,-3.793,2.467,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.100394,0.00821426,0.541079 kka2_1:4_Y244S,kka2_1:4_244,Kka2,kka2_1:4,P00552,0.54108,NO,244,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-0.775,-3.639,2.864,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.168804,0.00453187,0.54108 kka2_1:1_D208N,kka2_1:1_208,Kka2,kka2_1:1,P00552,0.541095,NO,208,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.708,-3.251,2.543,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.520039,0.00212588,0.541095 E1_Ubiquitin_H70H,E1_Ubiquitin_70,Uba1,E1_Ubiquitin,P0CG63,0.541114,NO,70,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-1.36,-1.36,,,0.05,E,B,0.61,-0.97,,,93.18,HBH,-1.146,0.18783,0.00206914,0.541114 E1_Ubiquitin_L43Q,E1_Ubiquitin_43,Uba1,E1_Ubiquitin,P0CG63,0.541114,NO,43,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.188,-3.935,2.747,,,E,B,,-1.17,,,,BHH,-1.30733,0.18783,0.00190185,0.541114 beta-lactamase_2500_A278D,beta-lactamase_2500_278,TEM-1,beta-lactamase_2500,P62593,0.541128,NO,278,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.361275,0.0310297,0.541128 kka2_1:2_K50E,kka2_1:2_50,Kka2,kka2_1:2,P00552,0.541245,NO,50,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-0.833,-3.062,2.229,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.295029,0.00138626,0.541245 beta-lactamase_0_L197K,beta-lactamase_0_197,TEM-1,beta-lactamase_0,P62593,0.541248,NO,197,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.853,-3.679,2.826,,0.007,S,B,0.55,0.33,1.087,,60.14,HHP,-1.833,0.0500837,0.00144602,0.541248 beta-lactamase_625_I93A,beta-lactamase_625_93,TEM-1,beta-lactamase_625,P62593,0.541307,NO,93,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.401,-3.13,1.729,,0.128,E,B,0.48,0.44,1.524,,67.83,BHB,-1.873,0.213352,0.00527066,0.541307 kka2_1:8_A119K,kka2_1:8_119,Kka2,kka2_1:8,P00552,0.541309,NO,119,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.073,-3.574,2.501,,0.019,H,A,0.46,-0.57,1.511,,71.59,AHH,-2.34,0.100394,0.00441074,0.541309 kka2_1:8_A119K,kka2_1:8_119,Kka2,kka2_1:8,P00552,0.541309,NO,119,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.073,-3.574,2.501,,0.019,H,A,0.46,-0.57,1.511,,71.59,AHH,-2.34,0.100394,0.00441074,0.541309 kka2_1:2_F133C,kka2_1:2_133,Kka2,kka2_1:2,P00552,0.541345,NO,133,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-0.871,-4.914,4.043,,0.178,.,B,0.58,0.43,1.999,,42.42,OHA,-0.871667,0.295029,0.00182168,0.541345 beta-lactamase_L47G,beta-lactamase_47,TEM-1,beta-lactamase,P62593,0.541346,NO,47,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.876,-3.777,1.901,5.27297,0.007,E,B,1.07,0.2,1.244,,67.83,AHA,-1.639,0.221079,0.00439844,0.541346 kka2_1:1_L103R,kka2_1:1_103,Kka2,kka2_1:1,P00552,0.541355,NO,103,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-2.362,-3.979,1.617,,0.394,T,A,0.55,-0.99,4.121,,63.64,HHP,-1.534,0.520039,0.00574792,0.541355 kka2_1:2_E262D,kka2_1:2_262,Kka2,kka2_1:2,P00552,0.541487,NO,262,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-0.829,-2.883,2.054,,0.059,G,A,1.04,-0.18,2.383,,42.42,AAH,-0.816,0.295029,0.0191586,0.541487 beta-lactamase_39_I261H,beta-lactamase_39_261,TEM-1,beta-lactamase_39,P62593,0.54153,NO,261,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.0495842,0.0123091,0.54153 beta-lactamase_625_N130D,beta-lactamase_625_130,TEM-1,beta-lactamase_625,P62593,0.541537,NO,130,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-0.798,-3.019,2.221,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.213352,0.000683376,0.541537 beta-lactamase_156_N274L,beta-lactamase_156_274,TEM-1,beta-lactamase_156,P62593,0.541594,NO,274,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.111618,0.0110418,0.541594 kka2_1:2_R147N,kka2_1:2_147,Kka2,kka2_1:2,P00552,0.541668,NO,147,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.123,-2.501,1.378,,0.094,H,A,1.2,0.97,0.425,,64.02,PBH,-1.98267,0.295029,0.00549168,0.541668 beta-lactamase_156_W227T,beta-lactamase_156_227,TEM-1,beta-lactamase_156,P62593,0.541671,NO,227,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-0.982,-3.696,2.714,,0.272,,B,0.47,-0.29,2.533,,74.48,OHH,-1.595,0.111618,0.00226019,0.541671 kka2_1:4_C77L,kka2_1:4_77,Kka2,kka2_1:4,P00552,0.54172,NO,77,C,L,CL,Special,Hydrophobic,5.07,9.7088,4.6388,198,121,131,10,108.5,166.7,58.2,-1.477,-3.33,1.853,,0.229,B,b,0.46,-0.57,2.499,,63.26,OOH,-1.55667,0.168804,0.00441216,0.54172 beta-lactamase_V31S,beta-lactamase_31,TEM-1,beta-lactamase,P62593,0.541815,NO,31,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.822,-3.594,1.772,5.43781,,H,A,2.78,-0.46,2.885,,73.78,BHB,-2.03767,0.221079,0.00478065,0.541815 gb1_G267F,gb1_267,gb1,gb1,P06654,0.541836,NO,267,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.676,-2.334,0.658,,,,,,,1.361,,12.72,AOA,-1.61833,0.177985,0.00264655,0.541836 beta-lactamase_2500_T116I,beta-lactamase_2500_116,TEM-1,beta-lactamase_2500,P62593,0.541897,NO,116,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.28,-3.822,2.542,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.361275,0.00336175,0.541897 beta-lactamase_K190P,beta-lactamase_190,TEM-1,beta-lactamase,P62593,0.541955,NO,190,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.994,-3.086,1.092,5.49163,0.371,H,A,1.82,0.16,29.753,29.753,77.62,BBH,-1.64167,0.221079,0.00574527,0.541955 beta-lactamase_625_L100E,beta-lactamase_625_100,TEM-1,beta-lactamase_625,P62593,0.542004,NO,100,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.218,-3.935,2.717,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.213352,0.00413885,0.542004 kka2_1:2_V49K,kka2_1:2_49,Kka2,kka2_1:2,P00552,0.542078,NO,49,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.614,-3.819,2.205,,,E,B,0.44,-0.77,1.233,,64.39,HHB,-1.3,0.295029,0.00615685,0.542078 beta-lactamase_A215M,beta-lactamase_215,TEM-1,beta-lactamase,P62593,0.54211,NO,215,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.503,-4.708,3.205,4.82164,,,a,0.75,-0.93,3.583,,74.48,HHO,-1.42633,0.221079,0.00544007,0.54211 beta-lactamase_39_L137R,beta-lactamase_39_137,TEM-1,beta-lactamase_39,P62593,0.542147,NO,137,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.03,-4,2.97,,,H,A,0.55,-0.38,0.674,,42.31,HHP,-1.58933,0.0495842,0.00278599,0.542147 kka2_1:2_E161I,kka2_1:2_161,Kka2,kka2_1:2,P00552,0.542429,NO,161,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.581,-3.91,2.329,,0.829,G,A,1.52,2.24,1.612,,92.05,AAB,-1.861,0.295029,0.00760103,0.542429 beta-lactamase_2500_Y103G,beta-lactamase_2500_103,TEM-1,beta-lactamase_2500,P62593,0.542481,NO,103,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-1.33,-3.527,2.197,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.361275,0.00443048,0.542481 kka2_1:4_L94F,kka2_1:4_94,Kka2,kka2_1:4,P00552,0.542515,NO,94,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.618,-3.805,2.187,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.168804,0.00520888,0.542515 kka2_1:4_G245T,kka2_1:4_245,Kka2,kka2_1:4,P00552,0.542603,NO,245,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.812,-3.629,2.817,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.168804,0.00683899,0.542603 beta-lactamase_R220T,beta-lactamase_220,TEM-1,beta-lactamase,P62593,0.542635,NO,220,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-0.942,-3.419,2.477,5.65995,0.295,I,A,0.68,-0.76,2.164,,74.48,HBP,-1.33633,0.221079,0.00232421,0.542635 kka2_1:4_A215R,kka2_1:4_215,Kka2,kka2_1:4,P00552,0.542741,NO,215,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.968,-3.821,2.853,,0.039,E,B,0.46,-0.59,0.754,,50.38,HHA,-1.00467,0.168804,0.00529129,0.542741 kka2_1:4_Q219G,kka2_1:4_219,Kka2,kka2_1:4,P00552,0.542886,NO,219,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-0.93,-3.41,2.48,,0.088,H,A,0.64,-0.85,1.537,,50,HPA,-1.05167,0.168804,0.00237913,0.542886 kka2_1:8_D208T,kka2_1:8_208,Kka2,kka2_1:8,P00552,0.542965,NO,208,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.708,-3.45,2.742,,0.36,,l,0.29,-1.01,,,,HAO,-0.929667,0.100394,0.00212588,0.542965 kka2_1:8_D208T,kka2_1:8_208,Kka2,kka2_1:8,P00552,0.542965,NO,208,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.708,-3.45,2.742,,0.36,,l,0.29,-1.01,,,,HAO,-0.929667,0.100394,0.00212588,0.542965 beta-lactamase_2500_V42C,beta-lactamase_2500_42,TEM-1,beta-lactamase_2500,P62593,0.54306,NO,42,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.564,-4.789,3.225,,0.017,E,B,0.44,-0.51,1.86,,63.99,BHO,-1.042,0.361275,0.00404515,0.54306 beta-lactamase_2500_V82K,beta-lactamase_2500_82,TEM-1,beta-lactamase_2500,P62593,0.543123,NO,82,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.325,-3.754,2.429,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.361275,0.00397046,0.543123 kka2_1:8_G30D,kka2_1:8_30,Kka2,kka2_1:8,P00552,0.543229,NO,30,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.596,-3.497,2.901,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.100394,0.00159208,0.543229 kka2_1:8_G30D,kka2_1:8_30,Kka2,kka2_1:8,P00552,0.543229,NO,30,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.596,-3.497,2.901,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.100394,0.00159208,0.543229 kka2_1:1_Q26T,kka2_1:1_26,Kka2,kka2_1:1,P00552,0.543245,NO,26,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.18,-3.677,1.497,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.520039,0.00708962,0.543245 kka2_1:2_D216Y,kka2_1:2_216,Kka2,kka2_1:2,P00552,0.543273,NO,216,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.785,-4.248,3.463,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.295029,0.00229969,0.543273 beta-lactamase_39_V31Y,beta-lactamase_39_31,TEM-1,beta-lactamase_39,P62593,0.543279,NO,31,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.822,-4.027,2.205,,,H,A,0.44,-0.46,2.885,,73.78,BHB,-2.03767,0.0495842,0.00478065,0.543279 kka2_1:8_W69Q,kka2_1:8_69,Kka2,kka2_1:8,P00552,0.543296,NO,69,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-0.859,-4.151,3.292,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.100394,0.0012874,0.543296 kka2_1:8_W69Q,kka2_1:8_69,Kka2,kka2_1:8,P00552,0.543296,NO,69,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-0.859,-4.151,3.292,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.100394,0.0012874,0.543296 beta-lactamase_L219R,beta-lactamase_219,TEM-1,beta-lactamase,P62593,0.543308,NO,219,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.313,-4.126,2.813,5.74153,,I,A,0.84,-0.51,2.321,,74.48,HHB,-1.21533,0.221079,0.00664345,0.543308 kka2_1:2_A237Q,kka2_1:2_237,Kka2,kka2_1:2,P00552,0.543314,NO,237,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.12,-4.238,2.118,,0.068,H,A,0.46,-0.71,2.369,,92.05,HHA,-2.10433,0.295029,0.012257,0.543314 beta-lactamase_L247Y,beta-lactamase_247,TEM-1,beta-lactamase,P62593,0.543357,NO,247,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.48,-4.1,2.62,5.28771,0.007,E,B,2.89,-0.72,2.951,,63.99,HHO,-1.79833,0.221079,0.00611275,0.543357 kka2_1:8_D190G,kka2_1:8_190,Kka2,kka2_1:8,P00552,0.543362,NO,190,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.708,-3.161,2.453,,0.213,S,b,0.29,-0.82,,,,OAH,-0.711667,0.100394,0.00247989,0.543362 kka2_1:8_D190G,kka2_1:8_190,Kka2,kka2_1:8,P00552,0.543362,NO,190,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.708,-3.161,2.453,,0.213,S,b,0.29,-0.82,,,,OAH,-0.711667,0.100394,0.00247989,0.543362 beta-lactamase_625_P181S,beta-lactamase_625_181,TEM-1,beta-lactamase_625,P62593,0.543449,NO,181,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.813,-3.349,2.536,,,H,A,0.52,-1.14,1.797,,61.54,HOH,-1.795,0.213352,0.000703122,0.543449 beta-lactamase_W286Q,beta-lactamase_286,TEM-1,beta-lactamase,P62593,0.543461,NO,286,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-1.111,-3.941,2.83,6.64456,0.492,,?,0.01,0.6,,,,BHX,-1.478,0.221079,,0.543461 beta-lactamase_2500_R202L,beta-lactamase_2500_202,TEM-1,beta-lactamase_2500,P62593,0.543483,NO,202,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.292,-3.422,2.13,,0.188,H,A,1.2,0.62,3.734,,77.62,PBP,-1.54767,0.361275,0.00321899,0.543483 kka2_1:1_Q252T,kka2_1:1_252,Kka2,kka2_1:1,P00552,0.543543,NO,252,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.63,-2.832,0.202,,0.906,H,A,0.64,0.35,1.369,,92.05,PPB,-2.20733,0.520039,0.0121001,0.543543 PSD95pdz3_L367D,PSD95pdz3_367,PSD95pdz3,PSD95pdz3,P31016,0.543612,NO,367,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.347,-3.825,2.478,5.47696,,,,,17.0063,,,,AHB,-1.39767,0.0758425,0.000466436,0.543612 beta-lactamase_2500_G85V,beta-lactamase_2500_85,TEM-1,beta-lactamase_2500,P62593,0.543637,NO,85,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.011,-3.796,2.785,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.361275,0.00252173,0.543637 kka2_1:2_D227A,kka2_1:2_227,Kka2,kka2_1:2,P00552,0.543689,NO,227,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.758,-2.851,1.093,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.295029,0.00745029,0.543689 beta-lactamase_0_D161V,beta-lactamase_0_161,TEM-1,beta-lactamase_0,P62593,0.543766,NO,161,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.891,-3.753,2.862,,0.341,,A,0.75,-0.52,0.795,,61.19,HAB,-0.961333,0.0500837,0.000897697,0.543766 beta-lactamase_2500_L135K,beta-lactamase_2500_135,TEM-1,beta-lactamase_2500,P62593,0.543792,NO,135,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.002,-3.751,2.749,,0.117,H,A,0.55,-0.58,0.795,,43.71,PHH,-1.03767,0.361275,0.00244423,0.543792 beta-lactamase_2500_P165R,beta-lactamase_2500_165,TEM-1,beta-lactamase_2500,P62593,0.54394,NO,165,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.373,-3.877,2.504,,0.203,T,A,0.52,-0.31,0.414,,73.78,AOA,-1.359,0.361275,0.00549538,0.54394 kka2_1:2_R147Q,kka2_1:2_147,Kka2,kka2_1:2,P00552,0.543961,NO,147,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.123,-2.836,1.713,,0.094,H,A,1.2,0.97,0.425,,64.02,PBH,-1.98267,0.295029,0.00549168,0.543961 beta-lactamase_V257S,beta-lactamase_257,TEM-1,beta-lactamase,P62593,0.543987,NO,257,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.533,-3.499,1.966,5.31999,,E,B,0.96,-0.7,1.463,,58.74,HHH,-1.70967,0.221079,0.00756629,0.543987 WW_domain_P174V,WW_domain_174,Yap65,WW_domain,P46937,0.543992,NO,174,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.035,-3.306,2.271,,,,,,,,,,HOH,-1.261,0.153962,0.000711366,0.543992 kka2_1:1_T130M,kka2_1:1_130,Kka2,kka2_1:1,P00552,0.544006,NO,130,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.392,-3.607,1.215,,0.561,G,A,0.22,0.77,0.5,,92.05,HPO,-1.62633,0.520039,0.00804204,0.544006 beta-lactamase_0_L120S,beta-lactamase_0_120,TEM-1,beta-lactamase_0,P62593,0.544074,NO,120,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.044,-3.66,2.616,,,H,A,0.55,-1.13,1.2,,64.69,AHO,-1.13633,0.0500837,0.00143563,0.544074 beta-lactamase_2500_A183L,beta-lactamase_2500_183,TEM-1,beta-lactamase_2500,P62593,0.54413,NO,183,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.231,-3.283,2.052,,0.155,H,A,0.46,-0.91,12.189,,77.62,HHH,-1.53367,0.361275,0.00296631,0.54413 beta-lactamase_2500_L191C,beta-lactamase_2500_191,TEM-1,beta-lactamase_2500,P62593,0.544139,NO,191,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.087,-4.696,3.609,,,H,A,0.55,0.09,1.703,,63.29,BHH,-1.445,0.361275,0.00263549,0.544139 kka2_1:2_L223K,kka2_1:2_223,Kka2,kka2_1:2,P00552,0.544156,NO,223,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.861,-3.793,2.932,,,H,A,0.55,-1.24,0.266,,50,HHH,-0.854333,0.295029,0.00253574,0.544156 beta-lactamase_G236C,beta-lactamase_236,TEM-1,beta-lactamase,P62593,0.544237,NO,236,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.784,-4.991,4.207,4.7915,0.241,,b,0.23,-0.59,1.883,,64.69,HOA,-1.36933,0.221079,0.00162372,0.544237 kka2_1:2_A222Y,kka2_1:2_222,Kka2,kka2_1:2,P00552,0.544255,NO,222,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.725,-4.191,3.466,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.295029,0.00207657,0.544255 beta-lactamase_2500_T116V,beta-lactamase_2500_116,TEM-1,beta-lactamase_2500,P62593,0.544276,NO,116,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.28,-3.415,2.135,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.361275,0.00336175,0.544276 kka2_1:1_A144V,kka2_1:1_144,Kka2,kka2_1:1,P00552,0.544306,NO,144,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.859,-2.095,1.236,,,H,A,0.46,0.21,0.842,,52.65,BHB,-1.72933,0.520039,0.00231095,0.544306 beta-lactamase_625_R257Q,beta-lactamase_625_257,TEM-1,beta-lactamase_625,P62593,0.544445,NO,257,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.213352,0.00756629,0.544445 beta-lactamase_2500_P143V,beta-lactamase_2500_143,TEM-1,beta-lactamase_2500,P62593,0.544524,NO,143,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.967,-3.311,2.344,,0.075,H,A,0.52,-0.37,0.479,,66.78,OOB,-1.354,0.361275,0.00114551,0.544524 beta-lactamase_T261G,beta-lactamase_261,TEM-1,beta-lactamase,P62593,0.544535,NO,261,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.88,-3.769,0.889,5.65483,0.014,E,B,0.53,-0.39,2.449,,77.62,HPP,-1.771,0.221079,0.0123091,0.544535 beta-lactamase_625_S51W,beta-lactamase_625_51,TEM-1,beta-lactamase_625,P62593,0.544586,NO,51,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.526,-5.435,3.909,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.213352,0.00504821,0.544586 gb1_L233W,gb1_233,gb1,gb1,P06654,0.544586,NO,233,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-2.678,-5.098,2.42,,,,,,,0.822,,45.54,HHP,-2.30267,0.177985,0.00266958,0.544586 gb1_Q258D,gb1_258,gb1,gb1,P06654,0.544586,NO,258,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.095,-2.12,0.025,,,,,,,0.86,,37.28,BPH,-1.88333,0.177985,0.00437595,0.544586 kka2_1:4_V185L,kka2_1:4_185,Kka2,kka2_1:4,P00552,0.54467,NO,185,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.045,-2.834,1.789,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.168804,0.00367031,0.54467 beta-lactamase_39_I277E,beta-lactamase_39_277,TEM-1,beta-lactamase_39,P62593,0.544676,NO,277,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.869,-4.006,2.137,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.0495842,0.0169305,0.544676 kka2_1:4_D90N,kka2_1:4_90,Kka2,kka2_1:4,P00552,0.54469,NO,90,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.459,-2.125,-0.334,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.168804,0.00583842,0.54469 beta-lactamase_2500_V82R,beta-lactamase_2500_82,TEM-1,beta-lactamase_2500,P62593,0.544719,NO,82,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.325,-4.101,2.776,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.361275,0.00397046,0.544719 kka2_1:2_D250L,kka2_1:2_250,Kka2,kka2_1:2,P00552,0.544809,NO,250,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.015,-3.81,2.795,,0.274,.,b,0.75,-0.46,3.796,,51.89,OAP,-1.83933,0.295029,0.0177103,0.544809 kka2_1:1_R226C,kka2_1:1_226,Kka2,kka2_1:1,P00552,0.544874,NO,226,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.392,-5.171,3.779,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.520039,0.0108032,0.544874 beta-lactamase_2500_P224Q,beta-lactamase_2500_224,TEM-1,beta-lactamase_2500,P62593,0.544876,NO,224,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.893,-3.868,2.975,,0.383,,B,0.52,-0.3,2.666,,74.48,HOH,-1.26433,0.361275,0.00189564,0.544876 WW_domain_Q195E,WW_domain_195,Yap65,WW_domain,P46937,0.544965,NO,195,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-1.839,-3.005,1.166,5.22735,,,,,,1.803,,70.04,APP,-1.719,0.153962,0.00394344,0.544965 kka2_1:8_L259D,kka2_1:8_259,Kka2,kka2_1:8,P00552,0.545008,NO,259,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.088,-4.066,2.978,,0.036,H,A,1.59,-0.15,1.83,,48.48,BHH,-1.15167,0.100394,0.0206964,0.545008 kka2_1:8_L259D,kka2_1:8_259,Kka2,kka2_1:8,P00552,0.545008,NO,259,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.088,-4.066,2.978,,0.036,H,A,1.59,-0.15,1.83,,48.48,BHH,-1.15167,0.100394,0.0206964,0.545008 beta-lactamase_625_L160G,beta-lactamase_625_160,TEM-1,beta-lactamase_625,P62593,0.545102,NO,160,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.977,-3.824,2.847,,0.022,,B,0.55,-0.6,0.237,,44.41,BHA,-0.936,0.213352,0.00193775,0.545102 kka2_1:2_A35P,kka2_1:2_35,Kka2,kka2_1:2,P00552,0.545127,NO,35,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.127,-4.029,1.902,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.295029,0.00630016,0.545127 kka2_1:1_T225D,kka2_1:1_225,Kka2,kka2_1:1,P00552,0.545205,NO,225,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.393,-3.922,1.529,,0.036,H,A,0.22,-1.22,4.554,,63.64,HPB,-1.58733,0.520039,0.0113598,0.545205 beta-lactamase_I45G,beta-lactamase_45,TEM-1,beta-lactamase,P62593,0.545254,NO,45,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-2.421,-3.565,1.144,5.31505,,E,B,1,-0.3,2.256,,77.62,HHA,-2.30267,0.221079,0.00452842,0.545254 kka2_1:1_K50E,kka2_1:1_50,Kka2,kka2_1:1,P00552,0.545294,NO,50,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-0.833,-3.062,2.229,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.520039,0.00138626,0.545294 beta-lactamase_2500_T198Y,beta-lactamase_2500_198,TEM-1,beta-lactamase_2500,P62593,0.545313,NO,198,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.168,-4.211,2.043,,0.489,,B,0.22,-0.13,0.37,,73.78,HPH,-1.98767,0.361275,0.004311,0.545313 beta-lactamase_625_R220C,beta-lactamase_625_220,TEM-1,beta-lactamase_625,P62593,0.545367,NO,220,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-0.942,-5.009,4.067,,0.295,I,A,1.2,-0.76,5.086,,74.48,HBP,-1.33633,0.213352,0.00232421,0.545367 kka2_1:1_L47K,kka2_1:1_47,Kka2,kka2_1:1,P00552,0.545424,NO,47,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.265,-3.649,2.384,,0.139,E,B,0.55,-0.86,14.593,14.593,63.26,HHH,-1.77933,0.520039,0.00509386,0.545424 kka2_1:1_I228V,kka2_1:1_228,Kka2,kka2_1:1,P00552,0.545512,NO,228,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.142,-1.946,0.804,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.520039,0.00458834,0.545512 kka2_1:1_E235A,kka2_1:1_235,Kka2,kka2_1:1,P00552,0.54552,NO,235,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.955,-1.909,-0.046,,0.631,H,A,1.52,0.12,8.521,,65.53,OAH,-2.07267,0.520039,0.0102806,0.54552 beta-lactamase_2500_H287D,beta-lactamase_2500_287,TEM-1,beta-lactamase_2500,P62593,0.545573,NO,287,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,,,,,,,,,,,,,BBH,-1.111,0.361275,,0.545573 beta-lactamase_625_E35C,beta-lactamase_625_35,TEM-1,beta-lactamase_625,P62593,0.545586,NO,35,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-0.869,-5.31,4.441,,0.15,H,A,1.04,0.21,0.664,,46.85,HAA,-1.88667,0.213352,0.00174441,0.545586 kka2_1:1_T85N,kka2_1:1_85,Kka2,kka2_1:1,P00552,0.545638,NO,85,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.165,-3.801,1.636,,0.576,E,B,0.82,1.39,16.653,16.653,71.59,HPA,-2.10133,0.520039,0.00634493,0.545638 kka2_1:2_G88N,kka2_1:2_88,Kka2,kka2_1:2,P00552,0.545709,NO,88,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.689,-2.869,1.18,,0.54,S,l,0.75,1.51,2.814,,65.53,HOB,-1.718,0.295029,0.00685559,0.545709 beta-lactamase_I243E,beta-lactamase_243,TEM-1,beta-lactamase,P62593,0.545716,NO,243,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.532,-2.774,1.242,5.26886,,E,B,1.68,-1.24,2.289,,50,OHH,-1.46867,0.221079,0.00464034,0.545716 kka2_1:1_F133S,kka2_1:1_133,Kka2,kka2_1:1,P00552,0.545724,NO,133,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-0.871,-3.662,2.791,,0.178,.,B,0.58,0.43,1.999,,42.42,OHA,-0.871667,0.520039,0.00182168,0.545724 beta-lactamase_I140W,beta-lactamase_140,TEM-1,beta-lactamase,P62593,0.545788,NO,140,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.733,-5.289,3.556,5.29918,0.128,H,A,1,0.41,1.16,,73.08,PHO,-1.48733,0.221079,0.00597777,0.545788 beta-lactamase_T126F,beta-lactamase_126,TEM-1,beta-lactamase,P62593,0.545788,NO,126,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.122,-4.199,3.077,4.82694,0.05,H,A,0.3,-0.05,1.14,,44.41,HPH,-1.60467,0.221079,0.00244552,0.545788 kka2_1:8_L19H,kka2_1:8_19,Kka2,kka2_1:8,P00552,0.545795,NO,19,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.254,-3.254,2,,0.08,T,A,1.59,-0.26,2.044,,65.53,BHH,-2.221,0.100394,0.00620703,0.545795 kka2_1:8_L19H,kka2_1:8_19,Kka2,kka2_1:8,P00552,0.545795,NO,19,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.254,-3.254,2,,0.08,T,A,1.59,-0.26,2.044,,65.53,BHH,-2.221,0.100394,0.00620703,0.545795 kka2_1:4_F256C,kka2_1:4_256,Kka2,kka2_1:4,P00552,0.545815,NO,256,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.49,-3.289,1.799,,,H,A,0.58,-0.78,1.653,,53.03,HHH,-1.423,0.168804,0.0132841,0.545815 kka2_1:8_P109Y,kka2_1:8_109,Kka2,kka2_1:8,P00552,0.545946,NO,109,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.412,-4.295,2.883,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.100394,0.0070929,0.545946 kka2_1:8_P109Y,kka2_1:8_109,Kka2,kka2_1:8,P00552,0.545946,NO,109,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.412,-4.295,2.883,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.100394,0.0070929,0.545946 beta-lactamase_0_E175Y,beta-lactamase_0_175,TEM-1,beta-lactamase_0,P62593,0.545999,NO,175,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.336,-4.303,1.967,,0.551,,A,1.04,1.05,2.334,,77.62,AAB,-1.31233,0.0500837,0.00482205,0.545999 kka2_1:1_I196T,kka2_1:1_196,Kka2,kka2_1:1,P00552,0.546046,NO,196,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-2.115,-3.682,1.567,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.520039,0.0107273,0.546046 kka2_1:8_F48A,kka2_1:8_48,Kka2,kka2_1:8,P00552,0.546057,NO,48,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.453,-3.34,1.887,,0.296,E,B,1.62,-0.99,14.194,14.194,55.3,HHH,-1.444,0.100394,0.00475422,0.546057 kka2_1:8_F48A,kka2_1:8_48,Kka2,kka2_1:8,P00552,0.546057,NO,48,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.453,-3.34,1.887,,0.296,E,B,1.62,-0.99,14.194,14.194,55.3,HHH,-1.444,0.100394,0.00475422,0.546057 beta-lactamase_0_L197Q,beta-lactamase_0_197,TEM-1,beta-lactamase_0,P62593,0.546082,NO,197,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.853,-4.122,3.269,,0.007,S,B,0.55,0.33,1.087,,60.14,HHP,-1.833,0.0500837,0.00144602,0.546082 beta-lactamase_2500_I125T,beta-lactamase_2500_125,TEM-1,beta-lactamase_2500,P62593,0.546149,NO,125,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.441,-2.752,1.311,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.361275,0.00383964,0.546149 kka2_1:1_A222S,kka2_1:1_222,Kka2,kka2_1:1,P00552,0.546152,NO,222,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.725,-2.964,2.239,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.520039,0.00207657,0.546152 kka2_1:2_E96H,kka2_1:2_96,Kka2,kka2_1:2,P00552,0.546173,NO,96,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.573,-4.74,2.167,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.295029,0.00369441,0.546173 beta-lactamase_156_F64I,beta-lactamase_156_64,TEM-1,beta-lactamase_156,P62593,0.54618,NO,64,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-0.841,-3.335,2.494,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.111618,0.000947691,0.54618 kka2_1:8_D216V,kka2_1:8_216,Kka2,kka2_1:8,P00552,0.546188,NO,216,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.785,-3.805,3.02,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.100394,0.00229969,0.546188 kka2_1:8_D216V,kka2_1:8_216,Kka2,kka2_1:8,P00552,0.546188,NO,216,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.785,-3.805,3.02,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.100394,0.00229969,0.546188 beta-lactamase_2500_G141M,beta-lactamase_2500_141,TEM-1,beta-lactamase_2500,P62593,0.546306,NO,141,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.828,-4.966,4.138,,0.575,T,l,0.29,-0.28,1.493,,64.69,HOO,-1.08933,0.361275,0.0012419,0.546306 beta-lactamase_2500_L146A,beta-lactamase_2500_146,TEM-1,beta-lactamase_2500,P62593,0.546326,NO,146,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.462,-3.204,1.742,,0.007,H,A,0.55,-0.56,1.578,,64.69,AHP,-1.656,0.361275,0.00474542,0.546326 kka2_1:1_P194L,kka2_1:1_194,Kka2,kka2_1:1,P00552,0.54636,NO,194,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.846,-3.652,2.806,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.520039,0.00314194,0.54636 kka2_1:2_R226A,kka2_1:2_226,Kka2,kka2_1:2,P00552,0.546479,NO,226,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.392,-3.272,1.88,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.295029,0.0108032,0.546479 kka2_1:2_R226V,kka2_1:2_226,Kka2,kka2_1:2,P00552,0.546479,NO,226,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.392,-3.893,2.501,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.295029,0.0108032,0.546479 kka2_1:2_P194N,kka2_1:2_194,Kka2,kka2_1:2,P00552,0.546587,NO,194,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.846,-3.808,2.962,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.295029,0.00314194,0.546587 beta-lactamase_2500_K30N,beta-lactamase_2500_30,TEM-1,beta-lactamase_2500,P62593,0.546596,NO,30,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-2.307,-2.865,0.558,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.361275,0.00448593,0.546596 beta-lactamase_L223G,beta-lactamase_223,TEM-1,beta-lactamase,P62593,0.546665,NO,223,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.055,-3.765,2.71,5.42318,0.27,,B,1.3,0.09,1.511,,74.48,HHO,-1.35033,0.221079,0.00372793,0.546665 kka2_1:1_L102D,kka2_1:1_102,Kka2,kka2_1:1,P00552,0.546672,NO,102,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.804,-4.17,3.366,,,T,A,0.55,-1.17,4.258,,42.42,AHH,-1.398,0.520039,0.00201332,0.546672 beta-lactamase_625_G154F,beta-lactamase_625_154,TEM-1,beta-lactamase_625,P62593,0.546704,NO,154,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.823,-4.328,3.505,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.213352,0.00180205,0.546704 beta-lactamase_2500_G85I,beta-lactamase_2500_85,TEM-1,beta-lactamase_2500,P62593,0.546716,NO,85,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.011,-4.226,3.215,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.361275,0.00252173,0.546716 kka2_1:8_F203E,kka2_1:8_203,Kka2,kka2_1:8,P00552,0.546716,NO,203,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-0.911,-3.952,3.041,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.100394,0.00318738,0.546716 kka2_1:8_F203E,kka2_1:8_203,Kka2,kka2_1:8,P00552,0.546716,NO,203,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-0.911,-3.952,3.041,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.100394,0.00318738,0.546716 beta-lactamase_S240M,beta-lactamase_240,TEM-1,beta-lactamase,P62593,0.546995,NO,240,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.537,-4.642,3.105,4.75024,,,B,0.74,-0.74,0.357,,65.38,OPB,-1.263,0.221079,0.00591201,0.546995 beta-lactamase_625_R91W,beta-lactamase_625_91,TEM-1,beta-lactamase_625,P62593,0.547022,NO,91,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.392,-5.388,3.996,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.213352,0.00380226,0.547022 kka2_1:8_W91Q,kka2_1:8_91,Kka2,kka2_1:8,P00552,0.547038,NO,91,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-1.178,-4.104,2.926,,0.077,E,B,1.51,0.27,2.51,,48.48,AHH,-1.51,0.100394,0.00358653,0.547038 kka2_1:8_W91Q,kka2_1:8_91,Kka2,kka2_1:8,P00552,0.547038,NO,91,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-1.178,-4.104,2.926,,0.077,E,B,1.51,0.27,2.51,,48.48,AHH,-1.51,0.100394,0.00358653,0.547038 kka2_1:1_G181E,kka2_1:1_181,Kka2,kka2_1:1,P00552,0.547054,NO,181,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-2.698,-2.628,-0.07,,0.379,S,B,0.75,0.78,15.356,15.356,71.59,AOA,-2.21,0.520039,0.00728319,0.547054 kka2_1:1_D33T,kka2_1:1_33,Kka2,kka2_1:1,P00552,0.547134,NO,33,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.186,-2.647,0.461,,0.561,S,A,0.75,3.35,2.568,,71.59,PAH,-1.306,0.520039,0.00633568,0.547134 beta-lactamase_A230W,beta-lactamase_230,TEM-1,beta-lactamase,P62593,0.547145,NO,230,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.154,-5.319,4.165,4.54336,0.01,E,B,0.75,-1.17,1.97,,50,HHA,-1.079,0.221079,0.00516841,0.547145 kka2_1:1_R226H,kka2_1:1_226,Kka2,kka2_1:1,P00552,0.547157,NO,226,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.392,-2.664,1.272,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.520039,0.0108032,0.547157 beta-lactamase_2500_E279W,beta-lactamase_2500_279,TEM-1,beta-lactamase_2500,P62593,0.547257,NO,279,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.361275,0.0192826,0.547257 kka2_1:2_L243V,kka2_1:2_243,Kka2,kka2_1:2,P00552,0.547282,NO,243,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-2.651,-2.869,0.218,,0.277,H,A,1.59,-0.67,13.165,13.165,92.05,HHH,-2.03767,0.295029,0.00884927,0.547282 gb1_A249R,gb1_249,gb1,gb1,P06654,0.547291,NO,249,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.739,-3.73,1.991,,,,,,,0.252,,44.87,AHH,-1.67367,0.177985,0.00333585,0.547291 gb1_F278I,gb1_278,gb1,gb1,P06654,0.547291,NO,278,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.418,-3.326,1.908,,,,,,,3.233,,35.71,PHP,-1.503,0.177985,0.00295699,0.547291 kka2_1:1_G74V,kka2_1:1_74,Kka2,kka2_1:1,P00552,0.547365,NO,74,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.18,-3.881,2.701,,0.621,T,l,0.75,0.2,15.356,15.356,64.39,POH,-1.91667,0.520039,0.00587035,0.547365 beta-lactamase_2500_S201Y,beta-lactamase_2500_201,TEM-1,beta-lactamase_2500,P62593,0.547369,NO,201,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.183,-4.222,3.039,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.361275,0.00198815,0.547369 beta-lactamase_2500_I244F,beta-lactamase_2500_244,TEM-1,beta-lactamase_2500,P62593,0.547624,NO,244,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.555,-3.842,2.287,,,E,B,0.48,-0.84,1.683,,77.62,OHH,-1.385,0.361275,0.00605379,0.547624 kka2_1:1_S104L,kka2_1:1_104,Kka2,kka2_1:1,P00552,0.547627,NO,104,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.436,-3.504,2.068,,0.536,T,A,0.27,-1.11,5.49,,63.64,HPP,-1.91433,0.520039,0.00555207,0.547627 kka2_1:1_L165Q,kka2_1:1_165,Kka2,kka2_1:1,P00552,0.5477,NO,165,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-2.453,-2.33,-0.123,,0.299,,B,1.59,1.12,2.47,,64.39,OHH,-1.90967,0.520039,0.00801161,0.5477 kka2_1:4_F206S,kka2_1:4_206,Kka2,kka2_1:4,P00552,0.547737,NO,206,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.349,-3.736,2.387,,0.006,E,B,0.58,-1.21,1.342,,63.64,OHH,-1.04,0.168804,0.00936868,0.547737 beta-lactamase_T27R,beta-lactamase_27,TEM-1,beta-lactamase,P62593,0.547771,NO,27,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.905,-3.861,1.956,5.39752,0.007,H,A,0.69,-0.37,0.745,,93.01,APH,-1.97933,0.221079,0.00306559,0.547771 beta-lactamase_2500_D174S,beta-lactamase_2500_174,TEM-1,beta-lactamase_2500,P62593,0.547946,NO,174,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.738,-3.161,2.423,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.361275,0.00125633,0.547946 beta-lactamase_625_R257S,beta-lactamase_625_257,TEM-1,beta-lactamase_625,P62593,0.547951,NO,257,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.213352,0.00756629,0.547951 beta-lactamase_2500_L89V,beta-lactamase_2500_89,TEM-1,beta-lactamase_2500,P62593,0.548099,NO,89,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.096,-3.043,1.947,,0.168,T,A,0.55,0.63,2.066,,64.34,PHO,-1.75767,0.361275,0.00207068,0.548099 beta-lactamase_2500_M66C,beta-lactamase_2500_66,TEM-1,beta-lactamase_2500,P62593,0.548118,NO,66,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.362,-4.734,3.372,,0.013,,A,0.55,-0.7,0.502,,73.08,OHH,-1.49567,0.361275,0.00412876,0.548118 beta-lactamase_39_T178W,beta-lactamase_39_178,TEM-1,beta-lactamase_39,P62593,0.548293,NO,178,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-0.791,-5.097,4.306,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.0495842,0.000684366,0.548293 beta-lactamase_I93M,beta-lactamase_93,TEM-1,beta-lactamase,P62593,0.548294,NO,93,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.401,-4.189,2.788,5.74695,0.128,E,B,0.77,0.44,1.757,,67.83,BHB,-1.873,0.221079,0.00527066,0.548294 beta-lactamase_2500_L55N,beta-lactamase_2500_55,TEM-1,beta-lactamase_2500,P62593,0.548363,NO,55,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.86,-4.216,2.356,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.361275,0.00403741,0.548363 beta-lactamase_R202W,beta-lactamase_202,TEM-1,beta-lactamase,P62593,0.548379,NO,202,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.292,-5.342,4.05,5.16273,0.188,H,A,0.68,0.62,1.918,,77.62,PBP,-1.54767,0.221079,0.00321899,0.548379 Ubiquitin_F4G,Ubiquitin_4,Uba1,Ubiquitin,P0CG48,0.548387,NO,4,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.534,-3.487,1.953,4.77459,0.059,E,B,,-0.46,,,,HHH,-1.504,0.205827,0.000805043,0.548387 Ubiquitin_R72C,Ubiquitin_72,Uba1,Ubiquitin,P0CG48,0.548387,NO,72,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.034,-3.401,1.367,5.19484,0.077,,B,1.41,-0.1,9.638,9.638,42.77,HBH,-1.82733,0.205827,0.000768249,0.548387 Ubiquitin_R72N,Ubiquitin_72,Uba1,Ubiquitin,P0CG48,0.548387,NO,72,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.034,-3.009,0.975,5.19484,0.077,,B,1.41,-0.1,9.638,9.638,42.77,HBH,-1.82733,0.205827,0.000768249,0.548387 beta-lactamase_625_S266W,beta-lactamase_625_266,TEM-1,beta-lactamase_625,P62593,0.548389,NO,266,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.213352,0.0140785,0.548389 Pab1_H172R,Pab1_172,Pab1,Pab1,P04147,0.548428,NO,172,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-1.21,-3.3,2.09,,0.076,E,B,0.35,-0.87,,,,HBH,-1.26667,0.175299,0.000296642,0.548428 kka2_1:1_V113A,kka2_1:1_113,Kka2,kka2_1:1,P00552,0.548436,NO,113,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.233,-2.573,1.34,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.520039,0.00650191,0.548436 kka2_1:4_F48V,kka2_1:4_48,Kka2,kka2_1:4,P00552,0.54844,NO,48,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.453,-2.048,0.595,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.168804,0.00475422,0.54844 beta-lactamase_L223N,beta-lactamase_223,TEM-1,beta-lactamase,P62593,0.548444,NO,223,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.055,-4.1,3.045,5.42318,0.27,,B,1.3,0.09,1.511,,74.48,HHO,-1.35033,0.221079,0.00372793,0.548444 kka2_1:1_D52H,kka2_1:1_52,Kka2,kka2_1:1,P00552,0.54856,NO,52,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.271,-4.302,2.031,,0.22,E,B,0.75,0.8,2.64,,71.59,PAH,-2.38367,0.520039,0.00175694,0.54856 kka2_1:2_I196D,kka2_1:2_196,Kka2,kka2_1:2,P00552,0.548679,NO,196,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-2.115,-4.156,2.041,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.295029,0.0107273,0.548679 kka2_1:4_H135R,kka2_1:4_135,Kka2,kka2_1:4,P00552,0.548737,NO,135,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-1.331,-2.597,1.266,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.168804,0.00532566,0.548737 kka2_1:8_L39D,kka2_1:8_39,Kka2,kka2_1:8,P00552,0.548764,NO,39,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.223,-4.127,2.904,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.100394,0.00493618,0.548764 kka2_1:8_L39D,kka2_1:8_39,Kka2,kka2_1:8,P00552,0.548764,NO,39,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.223,-4.127,2.904,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.100394,0.00493618,0.548764 PSD95pdz3_L379G,PSD95pdz3_379,PSD95pdz3,PSD95pdz3,P31016,0.548897,NO,379,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.347,-3.49,2.143,5.37777,,,,,16.8762,,,,HHB,-1.35667,0.0758425,0.00029733,0.548897 beta-lactamase_F64W,beta-lactamase_64,TEM-1,beta-lactamase,P62593,0.548941,NO,64,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-0.841,-4.422,3.581,5.70769,0.006,E,B,1.33,-0.95,,,,BHO,-0.892667,0.221079,0.000947691,0.548941 beta-lactamase_156_A34R,beta-lactamase_156_34,TEM-1,beta-lactamase_156,P62593,0.549004,NO,34,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.059,-4.061,2.002,,,H,A,0.46,-0.54,3.614,,73.78,AHA,-1.74967,0.111618,0.00407913,0.549004 beta-lactamase_2500_D231S,beta-lactamase_2500_231,TEM-1,beta-lactamase_2500,P62593,0.549143,NO,231,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.816,-3.186,2.37,,,E,B,0.75,-1.06,0.319,,65.38,HAB,-0.994,0.361275,0.00107395,0.549143 kka2_1:8_C131G,kka2_1:8_131,Kka2,kka2_1:8,P00552,0.549185,NO,131,C,G,CG,Special,Special,5.07,3.29388,-1.77612,159,121,75,-46,108.5,60.1,-48.4,-0.831,-3.611,2.78,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.100394,0.00170814,0.549185 kka2_1:8_C131G,kka2_1:8_131,Kka2,kka2_1:8,P00552,0.549185,NO,131,C,G,CG,Special,Special,5.07,3.29388,-1.77612,159,121,75,-46,108.5,60.1,-48.4,-0.831,-3.611,2.78,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.100394,0.00170814,0.549185 beta-lactamase_2500_I140T,beta-lactamase_2500_140,TEM-1,beta-lactamase_2500,P62593,0.549205,NO,140,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.733,-2.748,1.015,,0.128,H,A,0.48,0.41,1.628,,73.08,PHO,-1.48733,0.361275,0.00597777,0.549205 beta-lactamase_2500_S266M,beta-lactamase_2500_266,TEM-1,beta-lactamase_2500,P62593,0.549271,NO,266,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.361275,0.0140785,0.549271 beta-lactamase_625_V42N,beta-lactamase_625_42,TEM-1,beta-lactamase_625,P62593,0.549283,NO,42,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.564,-4.165,2.601,,0.017,E,B,0.44,-0.51,2.576,,63.99,BHO,-1.042,0.213352,0.00404515,0.549283 beta-lactamase_39_G234L,beta-lactamase_39_234,TEM-1,beta-lactamase_39,P62593,0.549405,NO,234,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.62,-3.808,3.188,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.0495842,0.000889577,0.549405 beta-lactamase_P65G,beta-lactamase_65,TEM-1,beta-lactamase,P62593,0.549432,NO,65,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.894,-3.443,2.549,5.59094,0.098,E,B,0.23,-0.62,0.623,,40.56,HOH,-1.03233,0.221079,0.00152776,0.549432 beta-lactamase_2500_I54K,beta-lactamase_2500_54,TEM-1,beta-lactamase_2500,P62593,0.549454,NO,54,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-2.838,-2.926,0.088,,0.669,E,B,0.48,-0.14,3.946,,73.78,BHH,-2.337,0.361275,0.00403589,0.549454 beta-lactamase_0_S256L,beta-lactamase_0_256,TEM-1,beta-lactamase_0,P62593,0.549483,NO,256,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.0500837,0.00710634,0.549483 beta-lactamase_2500_G76T,beta-lactamase_2500_76,TEM-1,beta-lactamase_2500,P62593,0.549558,NO,76,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.189,-2.655,1.466,,,H,A,0.29,-0.67,1.012,,67.83,OOH,-1.22267,0.361275,0.00476637,0.549558 beta-lactamase_156_E119W,beta-lactamase_156_119,TEM-1,beta-lactamase_156,P62593,0.54966,NO,119,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.412,-5.452,4.04,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.111618,0.00386966,0.54966 kka2_1:1_D180G,kka2_1:1_180,Kka2,kka2_1:1,P00552,0.549676,NO,180,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.416,-2.606,0.19,,1.03,S,a,0.75,1.5,1.534,,71.59,OAO,-2.02933,0.520039,0.00756412,0.549676 beta-lactamase_2500_L100Y,beta-lactamase_2500_100,TEM-1,beta-lactamase_2500,P62593,0.549688,NO,100,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.218,-2.879,1.661,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.361275,0.00413885,0.549688 kka2_1:8_W24N,kka2_1:8_24,Kka2,kka2_1:8,P00552,0.549768,NO,24,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-1.779,-4.301,2.522,,0.477,E,B,1.51,-0.21,2.503,,56.06,AHH,-2.24467,0.100394,0.00631564,0.549768 kka2_1:8_W24N,kka2_1:8_24,Kka2,kka2_1:8,P00552,0.549768,NO,24,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-1.779,-4.301,2.522,,0.477,E,B,1.51,-0.21,2.503,,56.06,AHH,-2.24467,0.100394,0.00631564,0.549768 kka2_1:8_R66T,kka2_1:8_66,Kka2,kka2_1:8,P00552,0.549833,NO,66,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-0.922,-3.484,2.562,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.100394,0.00161025,0.549833 kka2_1:8_R66T,kka2_1:8_66,Kka2,kka2_1:8,P00552,0.549833,NO,66,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-0.922,-3.484,2.562,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.100394,0.00161025,0.549833 beta-lactamase_0_M127P,beta-lactamase_0_127,TEM-1,beta-lactamase_0,P62593,0.549917,NO,127,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-2.251,-4.144,1.893,,0.312,S,A,0.55,0.32,9.35,9.35,72.73,PHP,-1.40433,0.0500837,0.00437927,0.549917 Pab1_F168W,Pab1_168,Pab1,Pab1,P04147,0.550153,NO,168,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.269,-4.233,2.964,,,,,,,0.789,,56.33,OHO,-1.10033,0.175299,0.00064061,0.550153 kka2_1:1_V242F,kka2_1:1_242,Kka2,kka2_1:1,P00552,0.550245,NO,242,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-2.687,-4.427,1.74,,0.75,H,A,0.44,-0.37,4.987,,71.59,HHH,-2.16533,0.520039,0.0102575,0.550245 beta-lactamase_2500_M270K,beta-lactamase_2500_270,TEM-1,beta-lactamase_2500,P62593,0.550305,NO,270,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.723,,,,0.422,H,A,1.59,1.15,2.029,,64.34,PHA,-1.70933,0.361275,0.00767762,0.550305 kka2_1:1_E169Q,kka2_1:1_169,Kka2,kka2_1:1,P00552,0.550462,NO,169,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.996,-2.511,0.515,,0.422,H,A,1.04,0.3,7.546,7.546,65.53,HAH,-1.755,0.520039,0.00730086,0.550462 beta-lactamase_0_V42D,beta-lactamase_0_42,TEM-1,beta-lactamase_0,P62593,0.550489,NO,42,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.564,-4.059,2.495,,0.017,E,B,0.44,-0.51,1.659,,63.99,BHO,-1.042,0.0500837,0.00404515,0.550489 beta-lactamase_2500_A230I,beta-lactamase_2500_230,TEM-1,beta-lactamase_2500,P62593,0.550509,NO,230,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.154,-3.843,2.689,,0.01,E,B,0.46,-1.17,1.171,,50,HHA,-1.079,0.361275,0.00516841,0.550509 kka2_1:2_G151F,kka2_1:2_151,Kka2,kka2_1:2,P00552,0.550651,NO,151,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.873,-4.384,3.511,,0.678,T,l,0.29,1.36,1.357,,49.62,HOH,-1.11433,0.295029,0.00339918,0.550651 beta-lactamase_625_N134T,beta-lactamase_625_134,TEM-1,beta-lactamase_625,P62593,0.550663,NO,134,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-0.879,-3.245,2.366,,0.138,H,A,0.61,-0.6,3.776,,53.15,HPH,-1.02233,0.213352,0.000644786,0.550663 kka2_1:2_L152N,kka2_1:2_152,Kka2,kka2_1:2,P00552,0.550699,NO,152,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.521,-4.061,2.54,,0.547,.,A,0.55,1.36,4.526,,63.64,OHH,-1.162,0.295029,0.00674868,0.550699 beta-lactamase_2500_G39W,beta-lactamase_2500_39,TEM-1,beta-lactamase_2500,P62593,0.550726,NO,39,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.864,-5.517,3.653,,0.701,T,L,0.29,0.47,29.926,29.926,77.62,HOH,-1.53633,0.361275,0.00487611,0.550726 beta-lactamase_L167E,beta-lactamase_167,TEM-1,beta-lactamase,P62593,0.550745,NO,167,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.138,-3.783,2.645,5.13111,0.015,G,A,0.08,-0.63,0.4,,64.69,AHP,-1.30767,0.221079,0.00303566,0.550745 beta-lactamase_156_T178H,beta-lactamase_156_178,TEM-1,beta-lactamase_156,P62593,0.550746,NO,178,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-0.791,-4.68,3.889,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.111618,0.000684366,0.550746 kka2_1:2_W236M,kka2_1:2_236,Kka2,kka2_1:2,P00552,0.550828,NO,236,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-1.363,-4.508,3.145,,0.303,H,A,1.51,-0.76,5.58,,48.48,AHH,-1.81267,0.295029,0.0088796,0.550828 kka2_1:2_W91S,kka2_1:2_91,Kka2,kka2_1:2,P00552,0.550851,NO,91,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-1.178,-3.808,2.63,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.295029,0.00358653,0.550851 beta-lactamase_2500_L89A,beta-lactamase_2500_89,TEM-1,beta-lactamase_2500,P62593,0.550889,NO,89,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.096,-2.465,1.369,,0.168,T,A,0.55,0.63,2.066,,64.34,PHO,-1.75767,0.361275,0.00207068,0.550889 kka2_1:2_R38S,kka2_1:2_38,Kka2,kka2_1:2,P00552,0.550906,NO,38,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.207,-3.563,2.356,,0.355,E,B,1.2,-1.13,6.872,6.872,52.27,HBH,-1.28567,0.295029,0.00372499,0.550906 kka2_1:8_V185E,kka2_1:8_185,Kka2,kka2_1:8,P00552,0.550932,NO,185,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.045,-3.799,2.754,,0.058,E,B,1.48,-0.49,1.234,,46.97,HHH,-1.184,0.100394,0.00367031,0.550932 kka2_1:8_V185E,kka2_1:8_185,Kka2,kka2_1:8,P00552,0.550932,NO,185,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.045,-3.799,2.754,,0.058,E,B,1.48,-0.49,1.234,,46.97,HHH,-1.184,0.100394,0.00367031,0.550932 kka2_1:1_D250A,kka2_1:1_250,Kka2,kka2_1:1,P00552,0.551074,NO,250,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.015,-3.315,2.3,,0.274,.,b,0.75,-0.46,4.177,,51.89,OAP,-1.83933,0.520039,0.0177103,0.551074 beta-lactamase_M209A,beta-lactamase_209,TEM-1,beta-lactamase,P62593,0.551091,NO,209,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.442,-3.177,1.735,5.44502,,H,A,1.75,-0.97,1.402,,64.69,HHA,-1.52633,0.221079,0.00625021,0.551091 kka2_1:2_P179H,kka2_1:2_179,Kka2,kka2_1:2,P00552,0.551119,NO,179,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.974,-4.803,3.829,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.295029,0.00298346,0.551119 kka2_1:1_F48Q,kka2_1:1_48,Kka2,kka2_1:1,P00552,0.551141,NO,48,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.453,-4.352,2.899,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.520039,0.00475422,0.551141 kka2_1:1_T73V,kka2_1:1_73,Kka2,kka2_1:1,P00552,0.551177,NO,73,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.51,-2.513,0.003,,0.309,H,A,0.22,0.35,4.126,,56.06,PPO,-2.02333,0.520039,0.00628605,0.551177 beta-lactamase_39_D155L,beta-lactamase_39_155,TEM-1,beta-lactamase_39,P62593,0.551246,NO,155,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.889,-3.807,2.918,,0.049,,B,0.75,-0.9,3.208,,64.69,OAB,-1.62267,0.0495842,0.00135315,0.551246 beta-lactamase_R271W,beta-lactamase_271,TEM-1,beta-lactamase,P62593,0.551333,NO,271,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.249,-5.317,4.068,5.24516,0.085,H,A,1.67,-0.05,0.474,,63.99,ABP,-1.36633,0.221079,0.00752082,0.551333 kka2_1:2_R38E,kka2_1:2_38,Kka2,kka2_1:2,P00552,0.551333,NO,38,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.207,-3.518,2.311,,0.355,E,B,1.2,-1.13,6.872,6.872,52.27,HBH,-1.28567,0.295029,0.00372499,0.551333 kka2_1:2_R38Y,kka2_1:2_38,Kka2,kka2_1:2,P00552,0.551333,NO,38,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.207,-4.179,2.972,,0.355,E,B,1.2,-1.13,6.872,6.872,52.27,HBH,-1.28567,0.295029,0.00372499,0.551333 beta-lactamase_625_H287I,beta-lactamase_625_287,TEM-1,beta-lactamase_625,P62593,0.551343,NO,287,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,,,,,,,,,,,,,BBH,-1.111,0.213352,,0.551343 kka2_1:1_A56V,kka2_1:1_56,Kka2,kka2_1:1,P00552,0.551351,NO,56,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.083,-2.653,0.57,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.520039,0.00717715,0.551351 kka2_1:4_F240S,kka2_1:4_240,Kka2,kka2_1:4,P00552,0.551373,NO,240,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-0.911,-3.673,2.762,,,H,A,0.58,-1.21,5.798,,50.38,BHH,-1.67267,0.168804,0.00552543,0.551373 beta-lactamase_625_E46R,beta-lactamase_625_46,TEM-1,beta-lactamase_625,P62593,0.551386,NO,46,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.94,-4.04,2.1,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.213352,0.00427568,0.551386 kka2_1:2_L103I,kka2_1:2_103,Kka2,kka2_1:2,P00552,0.551401,NO,103,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-2.362,-3.505,1.143,,0.394,T,A,0.55,-0.99,3.499,,63.64,HHP,-1.534,0.295029,0.00574792,0.551401 beta-lactamase_2500_L89H,beta-lactamase_2500_89,TEM-1,beta-lactamase_2500,P62593,0.551435,NO,89,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.096,-4.892,3.796,,0.168,T,A,0.55,0.63,2.066,,64.34,PHO,-1.75767,0.361275,0.00207068,0.551435 kka2_1:1_E199Q,kka2_1:1_199,Kka2,kka2_1:1,P00552,0.551439,NO,199,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.234,-3.039,0.805,,0.508,E,B,1.04,-0.43,3.012,,65.53,HAP,-2.133,0.520039,0.00854122,0.551439 kka2_1:4_R147I,kka2_1:4_147,Kka2,kka2_1:4,P00552,0.551454,NO,147,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.123,-4.139,3.016,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.168804,0.00549168,0.551454 kka2_1:2_W91Q,kka2_1:2_91,Kka2,kka2_1:2,P00552,0.551461,NO,91,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-1.178,-4.104,2.926,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.295029,0.00358653,0.551461 beta-lactamase_2500_V106G,beta-lactamase_2500_106,TEM-1,beta-lactamase_2500,P62593,0.551506,NO,106,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.218,-3.752,2.534,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.361275,0.00304168,0.551506 beta-lactamase_625_L188W,beta-lactamase_625_188,TEM-1,beta-lactamase_625,P62593,0.551664,NO,188,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.166,-3.108,1.942,,,H,A,0.55,-0.3,2.982,,60.14,PHB,-1.47033,0.213352,0.00295687,0.551664 kka2_1:1_P12S,kka2_1:1_12,Kka2,kka2_1:1,P00552,0.55168,NO,12,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.853,-3.336,2.483,,,.,B,0.52,1.25,0.261,,48.11,POH,-1.80767,0.520039,0.00500011,0.55168 PSD95pdz3_I388Y,PSD95pdz3_388,PSD95pdz3,PSD95pdz3,P31016,0.551738,NO,388,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.63,-3.619,1.989,5.17282,,,,,16.0025,,,,PHH,-1.54967,0.0758425,0.000151216,0.551738 beta-lactamase_2500_F228I,beta-lactamase_2500_228,TEM-1,beta-lactamase_2500,P62593,0.551755,NO,228,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-2.342,-3.049,0.707,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.361275,0.0046669,0.551755 beta-lactamase_2500_L38P,beta-lactamase_2500_38,TEM-1,beta-lactamase_2500,P62593,0.551759,NO,38,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.343,-2.934,1.591,,0.088,H,A,0.55,0.2,2.71,,64.34,PHO,-1.78033,0.361275,0.00373244,0.551759 kka2_1:2_E182D,kka2_1:2_182,Kka2,kka2_1:2,P00552,0.551798,NO,182,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.516,-2.787,1.271,,0.326,,B,1.52,0.75,14.547,14.547,65.53,OAA,-1.806,0.295029,0.00641548,0.551798 beta-lactamase_W208E,beta-lactamase_208,TEM-1,beta-lactamase,P62593,0.551821,NO,208,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-0.818,-3.89,3.072,5.26277,0.067,H,A,0.99,-0.65,,,,AHH,-1.44133,0.221079,0.00126609,0.551821 kka2_1:8_V153N,kka2_1:8_153,Kka2,kka2_1:8,P00552,0.551833,NO,153,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.092,-4.209,3.117,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.100394,0.00501119,0.551833 kka2_1:8_V153N,kka2_1:8_153,Kka2,kka2_1:8,P00552,0.551833,NO,153,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.092,-4.209,3.117,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.100394,0.00501119,0.551833 kka2_1:1_S40G,kka2_1:1_40,Kka2,kka2_1:1,P00552,0.551838,NO,40,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.645,-3.566,0.921,,0.32,E,B,0.27,-0.9,25.997,25.997,71.59,HPH,-1.91567,0.520039,0.00693477,0.551838 beta-lactamase_D161G,beta-lactamase_161,TEM-1,beta-lactamase,P62593,0.551918,NO,161,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.891,-3.177,2.286,5.12208,0.341,,A,0.23,-0.52,1.602,,61.19,HAB,-0.961333,0.221079,0.000897697,0.551918 beta-lactamase_156_D174P,beta-lactamase_156_174,TEM-1,beta-lactamase_156,P62593,0.551968,NO,174,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.738,-3.655,2.917,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.111618,0.00125633,0.551968 beta-lactamase_156_V117G,beta-lactamase_156_117,TEM-1,beta-lactamase_156,P62593,0.551983,NO,117,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.53,-3.828,2.298,,,H,A,0.44,-0.34,1.182,,65.03,PHB,-1.741,0.111618,0.00467906,0.551983 kka2_1:2_F263L,kka2_1:2_263,Kka2,kka2_1:2,P00552,0.551997,NO,263,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-0.911,-2.161,1.25,,0.006,G,A,1.62,-0.12,5.275,,45.83,AHH,-0.92,0.295029,0.0172454,0.551997 beta-lactamase_L146G,beta-lactamase_146,TEM-1,beta-lactamase,P62593,0.552028,NO,146,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.462,-3.742,2.28,5.62483,0.007,H,A,1.3,-0.56,1.953,,64.69,AHP,-1.656,0.221079,0.00474542,0.552028 beta-lactamase_2500_R81G,beta-lactamase_2500_81,TEM-1,beta-lactamase_2500,P62593,0.552051,NO,81,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.466,-2.66,1.194,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.361275,0.00499763,0.552051 kka2_1:4_T146P,kka2_1:4_146,Kka2,kka2_1:4,P00552,0.552062,NO,146,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.978,-4.011,1.033,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.168804,0.00606474,0.552062 beta-lactamase_156_L205E,beta-lactamase_156_205,TEM-1,beta-lactamase_156,P62593,0.552073,NO,205,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.922,-3.908,2.986,,,H,A,0.55,-0.46,0.678,,42.31,PHH,-1.57767,0.111618,0.00255802,0.552073 beta-lactamase_2500_D99Y,beta-lactamase_2500_99,TEM-1,beta-lactamase_2500,P62593,0.552085,NO,99,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.191,-4.234,3.043,,0.402,G,A,0.75,0.36,1.318,,64.69,PAH,-1.794,0.361275,0.00305446,0.552085 kka2_1:1_G201R,kka2_1:1_201,Kka2,kka2_1:1,P00552,0.552116,NO,201,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.56,-2.756,1.196,,0.149,T,l,0.29,-0.57,16.092,16.092,52.65,POB,-1.92233,0.520039,0.00820117,0.552116 beta-lactamase_2500_L74T,beta-lactamase_2500_74,TEM-1,beta-lactamase_2500,P62593,0.552212,NO,74,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.296,-3.432,2.136,,,H,A,0.55,-0.91,0.746,,50,HHO,-1.34933,0.361275,0.00493255,0.552212 PSD95pdz3_A347Q,PSD95pdz3_347,PSD95pdz3,PSD95pdz3,P31016,0.552224,NO,347,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.307,-3.581,2.274,4.89689,,,,,15.176,,,,OHA,-1.269,0.0758425,0.00074525,0.552224 beta-lactamase_2500_P224R,beta-lactamase_2500_224,TEM-1,beta-lactamase_2500,P62593,0.552288,NO,224,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.893,-2.763,1.87,,0.383,,B,0.52,-0.3,2.666,,74.48,HOH,-1.26433,0.361275,0.00189564,0.552288 beta-lactamase_156_D83P,beta-lactamase_156_83,TEM-1,beta-lactamase_156,P62593,0.552299,NO,83,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.066,-3.748,2.682,,0.354,H,A,0.75,0.22,1.281,,48.95,HAH,-1.34733,0.111618,0.00205968,0.552299 beta-lactamase_625_L120T,beta-lactamase_625_120,TEM-1,beta-lactamase_625,P62593,0.552309,NO,120,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.044,-3.547,2.503,,,H,A,0.55,-1.13,7.813,,64.69,AHO,-1.13633,0.213352,0.00143563,0.552309 kka2_1:8_L19P,kka2_1:8_19,Kka2,kka2_1:8,P00552,0.552348,NO,19,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.254,-4.281,3.027,,0.08,T,A,1.59,-0.26,2.044,,65.53,BHH,-2.221,0.100394,0.00620703,0.552348 kka2_1:8_L19P,kka2_1:8_19,Kka2,kka2_1:8,P00552,0.552348,NO,19,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.254,-4.281,3.027,,0.08,T,A,1.59,-0.26,2.044,,65.53,BHH,-2.221,0.100394,0.00620703,0.552348 beta-lactamase_N134F,beta-lactamase_134,TEM-1,beta-lactamase,P62593,0.552549,NO,134,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-0.879,-4.318,3.439,5.07245,0.138,H,A,0.09,-0.6,1.441,,53.15,HPH,-1.02233,0.221079,0.000644786,0.552549 gb1_V265Y,gb1_265,gb1,gb1,P06654,0.552567,NO,265,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.843,-4.009,2.166,,,,,,,0.402,,11.83,OHA,-1.64567,0.177985,0.00360613,0.552567 kka2_1:2_C131R,kka2_1:2_131,Kka2,kka2_1:2,P00552,0.552624,NO,131,C,R,CR,Special,PositiveCharge,5.07,6.34148,1.27148,180,121,174,53,108.5,173.4,64.9,-0.831,-4.186,3.355,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.295029,0.00170814,0.552624 beta-lactamase_156_T131K,beta-lactamase_156_131,TEM-1,beta-lactamase_156,P62593,0.552632,NO,131,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.328,-3.481,2.153,,,H,A,0.22,-0.69,2.031,,67.48,PPH,-1.00867,0.111618,0.00345886,0.552632 beta-lactamase_156_G240D,beta-lactamase_156_240,TEM-1,beta-lactamase_156,P62593,0.552781,NO,240,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.111618,0.00591201,0.552781 Pab1_I196H,Pab1_196,Pab1,Pab1,P04147,0.552823,NO,196,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.795,-4.798,3.003,,,,,,,2.013,,80.59,AHH,-1.44667,0.175299,0.0016933,0.552823 kka2_1:8_L170G,kka2_1:8_170,Kka2,kka2_1:8,P00552,0.552849,NO,170,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.28,-3.713,2.433,,0.029,H,A,1.59,0.11,1.453,,62.5,AHH,-1.534,0.100394,0.00730791,0.552849 kka2_1:8_L170G,kka2_1:8_170,Kka2,kka2_1:8,P00552,0.552849,NO,170,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.28,-3.713,2.433,,0.029,H,A,1.59,0.11,1.453,,62.5,AHH,-1.534,0.100394,0.00730791,0.552849 beta-lactamase_W286N,beta-lactamase_286,TEM-1,beta-lactamase,P62593,0.553027,NO,286,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-1.111,-4.165,3.054,6.64456,0.492,,?,0.01,0.6,,,,BHX,-1.478,0.221079,,0.553027 kka2_1:8_I115S,kka2_1:8_115,Kka2,kka2_1:8,P00552,0.553054,NO,115,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.606,-2.994,1.388,,0.105,H,A,1.52,-1.18,4.064,,65.53,PHH,-2.205,0.100394,0.00836567,0.553054 kka2_1:8_I115S,kka2_1:8_115,Kka2,kka2_1:8,P00552,0.553054,NO,115,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.606,-2.994,1.388,,0.105,H,A,1.52,-1.18,4.064,,65.53,PHH,-2.205,0.100394,0.00836567,0.553054 kka2_1:4_R66L,kka2_1:4_66,Kka2,kka2_1:4,P00552,0.553134,NO,66,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-0.922,-3.421,2.499,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.168804,0.00161025,0.553134 kka2_1:1_A41R,kka2_1:1_41,Kka2,kka2_1:1,P00552,0.553195,NO,41,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.879,-2.71,0.831,,0.184,.,B,0.46,-0.96,18.207,18.207,64.39,PHP,-2.477,0.520039,0.00543332,0.553195 beta-lactamase_39_D33P,beta-lactamase_39_33,TEM-1,beta-lactamase_39,P62593,0.55322,NO,33,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.321,-3.968,1.647,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.0495842,0.00435556,0.55322 beta-lactamase_G239C,beta-lactamase_239,TEM-1,beta-lactamase,P62593,0.553224,NO,239,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.819,-5.016,4.197,4.85529,0.115,T,l,0.77,-0.62,1.817,,42.31,BOP,-1.45267,0.221079,0.00213852,0.553224 beta-lactamase_2500_L73Q,beta-lactamase_2500_73,TEM-1,beta-lactamase_2500,P62593,0.553246,NO,73,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.507,-4.261,2.754,,,H,A,0.55,-0.64,2.178,,67.83,HHH,-1.487,0.361275,0.00488983,0.553246 beta-lactamase_L49R,beta-lactamase_49,TEM-1,beta-lactamase,P62593,0.553277,NO,49,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.897,-3.032,1.135,5.86005,0.131,T,A,1.3,0.04,3.112,,64.69,AHP,-1.99233,0.221079,0.00401477,0.553277 beta-lactamase_2500_S201K,beta-lactamase_2500_201,TEM-1,beta-lactamase_2500,P62593,0.553283,NO,201,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.183,-3.387,2.204,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.361275,0.00198815,0.553283 beta-lactamase_2500_P217F,beta-lactamase_2500_217,TEM-1,beta-lactamase_2500,P62593,0.55335,NO,217,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-2.062,-4.432,2.37,,0.496,I,A,0.52,-0.33,0.431,,74.48,OOH,-1.64333,0.361275,0.00463211,0.55335 beta-lactamase_2500_A215M,beta-lactamase_2500_215,TEM-1,beta-lactamase_2500,P62593,0.553377,NO,215,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.503,-4.708,3.205,,,,a,0.46,-0.93,3.516,,74.48,HHO,-1.42633,0.361275,0.00544007,0.553377 beta-lactamase_2500_A235M,beta-lactamase_2500_235,TEM-1,beta-lactamase_2500,P62593,0.553439,NO,235,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.266,-4.612,3.346,,0.32,E,B,0.46,-0.86,0.891,,50,OHO,-0.89,0.361275,0.00493474,0.553439 Pab1_F173V,Pab1_173,Pab1,Pab1,P04147,0.553487,NO,173,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.477,-3.192,1.715,,,E,B,0.87,-0.16,1.636,,63.26,BHA,-1.36967,0.175299,0.00148779,0.553487 beta-lactamase_625_I54G,beta-lactamase_625_54,TEM-1,beta-lactamase_625,P62593,0.553713,NO,54,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-2.838,-3.612,0.774,,0.669,E,B,0.48,-0.14,3.946,,73.78,BHH,-2.337,0.213352,0.00403589,0.553713 kka2_1:1_A255D,kka2_1:1_255,Kka2,kka2_1:1,P00552,0.553728,NO,255,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.715,-2.352,0.637,,0.466,H,A,0.46,-0.52,0.946,,65.53,HHH,-1.71267,0.520039,0.0126809,0.553728 beta-lactamase_39_T69F,beta-lactamase_39_69,TEM-1,beta-lactamase_39,P62593,0.553729,NO,69,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-0.973,-4.127,3.154,,,G,A,0.22,-1.24,4.194,,93.01,PPH,-1.01833,0.0495842,0.00127498,0.553729 beta-lactamase_2500_R242K,beta-lactamase_2500_242,TEM-1,beta-lactamase_2500,P62593,0.553755,NO,242,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.361275,0.00452879,0.553755 PSD95pdz3_G345V,PSD95pdz3_345,PSD95pdz3,PSD95pdz3,P31016,0.553764,NO,345,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.008,-3.435,2.427,4.32868,,,,,13.165,,,,OOO,-1.084,0.0758425,0.000771806,0.553764 kka2_1:1_G30D,kka2_1:1_30,Kka2,kka2_1:1,P00552,0.553766,NO,30,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.596,-3.497,2.901,,0.54,S,g,0.29,3.76,,,,HOO,-1.51133,0.520039,0.00159208,0.553766 beta-lactamase_625_T158V,beta-lactamase_625_158,TEM-1,beta-lactamase_625,P62593,0.553789,NO,158,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.116,-3.299,2.183,,0.036,,B,0.22,-0.85,3.771,,69.58,HPB,-1.269,0.213352,0.00341825,0.553789 beta-lactamase_2500_P105E,beta-lactamase_2500_105,TEM-1,beta-lactamase_2500,P62593,0.553817,NO,105,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.813,-3.437,2.624,,0.226,T,A,0.52,0.8,3.1,,63.29,POH,-1.01533,0.361275,0.0011981,0.553817 beta-lactamase_156_T178E,beta-lactamase_156_178,TEM-1,beta-lactamase_156,P62593,0.553835,NO,178,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-0.791,-3.44,2.649,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.111618,0.000684366,0.553835 beta-lactamase_G248H,beta-lactamase_248,TEM-1,beta-lactamase,P62593,0.553932,NO,248,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.794,-4.745,2.951,4.69798,,E,b,0.23,-0.43,1.782,,61.19,HOO,-1.52867,0.221079,0.00428493,0.553932 beta-lactamase_39_G240V,beta-lactamase_39_240,TEM-1,beta-lactamase_39,P62593,0.553958,NO,240,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.0495842,0.00591201,0.553958 beta-lactamase_0_L284K,beta-lactamase_0_284,TEM-1,beta-lactamase_0,P62593,0.554095,NO,284,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.981,-3.504,1.523,,0.848,H,A,2.89,0.67,4.544,,77.62,PHH,-1.82133,0.0500837,0.0686156,0.554095 beta-lactamase_0_M127H,beta-lactamase_0_127,TEM-1,beta-lactamase_0,P62593,0.554141,NO,127,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-2.251,-4.786,2.535,,0.312,S,A,0.55,0.32,9.35,9.35,72.73,PHP,-1.40433,0.0500837,0.00437927,0.554141 kka2_1:8_I207F,kka2_1:8_207,Kka2,kka2_1:8,P00552,0.554141,NO,207,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.175,-3.792,2.617,,0.293,,B,1.52,-1.12,1.306,,56.06,HHA,-1.07733,0.100394,0.00611824,0.554141 kka2_1:8_I207F,kka2_1:8_207,Kka2,kka2_1:8,P00552,0.554141,NO,207,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.175,-3.792,2.617,,0.293,,B,1.52,-1.12,1.306,,56.06,HHA,-1.07733,0.100394,0.00611824,0.554141 kka2_1:4_A64P,kka2_1:4_64,Kka2,kka2_1:4,P00552,0.554144,NO,64,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.496,-4.02,2.524,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.168804,0.00705578,0.554144 beta-lactamase_S233V,beta-lactamase_233,TEM-1,beta-lactamase,P62593,0.55425,NO,233,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.886,-3.357,1.471,4.98121,0.016,E,B,0.48,-1.01,5.361,,77.62,BPO,-1.17267,0.221079,0.00311415,0.55425 beta-lactamase_156_Y262W,beta-lactamase_156_262,TEM-1,beta-lactamase_156,P62593,0.554258,NO,262,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.111618,0.00853516,0.554258 kka2_1:2_K50V,kka2_1:2_50,Kka2,kka2_1:2,P00552,0.55427,NO,50,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-0.833,-3.601,2.768,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.295029,0.00138626,0.55427 Pab1_Y197E,Pab1_197,Pab1,Pab1,P04147,0.554282,NO,197,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-1.345,-3.66,2.315,,,,,,,0.891,,80.42,HHH,-1.41767,0.175299,0.00302474,0.554282 Pab1_F129I,Pab1_129,Pab1,Pab1,P04147,0.554344,NO,129,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.269,-3.256,1.987,,0.219,E,B,0.03,-0.07,1.307,,73.83,HHH,-1.27533,0.175299,0.000625182,0.554344 kka2_1:2_V214K,kka2_1:2_214,Kka2,kka2_1:2,P00552,0.554375,NO,214,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.261,-3.816,2.555,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.295029,0.00692782,0.554375 beta-lactamase_156_T107F,beta-lactamase_156_107,TEM-1,beta-lactamase_156,P62593,0.554389,NO,107,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.117,-4.119,3.002,,,G,A,0.22,-0.06,0.341,,67.83,HPA,-1.265,0.111618,0.00239347,0.554389 beta-lactamase_2500_G265R,beta-lactamase_2500_265,TEM-1,beta-lactamase_2500,P62593,0.554435,NO,265,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.361275,0.00811926,0.554435 kka2_1:1_E160G,kka2_1:1_160,Kka2,kka2_1:1,P00552,0.554457,NO,160,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.683,-3.367,1.684,,0.989,G,A,1.04,2.28,0.273,,71.59,AAA,-1.36133,0.520039,0.00935762,0.554457 Pab1_T145P,Pab1_145,Pab1,Pab1,P04147,0.554482,NO,145,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.067,-3.472,2.405,,0.237,H,A,0.3,0.69,,,,APH,-1.135,0.175299,0.000331088,0.554482 beta-lactamase_2500_V214G,beta-lactamase_2500_214,TEM-1,beta-lactamase_2500,P62593,0.554532,NO,214,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.299,-3.571,2.272,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.361275,0.00628442,0.554532 beta-lactamase_0_I171F,beta-lactamase_0_171,TEM-1,beta-lactamase_0,P62593,0.554669,NO,171,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-2.431,-3.175,0.744,,0.361,,B,0.48,0.53,16.954,16.954,77.62,HHO,-1.55533,0.0500837,0.00623355,0.554669 beta-lactamase_2500_V82W,beta-lactamase_2500_82,TEM-1,beta-lactamase_2500,P62593,0.554736,NO,82,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.325,-5.421,4.096,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.361275,0.00397046,0.554736 WW_domain_N191C,WW_domain_191,Yap65,WW_domain,P46937,0.554746,NO,191,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-1.519,-4.839,3.32,5.96016,,,,,,5.117,,66.07,HPB,-1.554,0.153962,0.00270999,0.554746 kka2_1:4_L70F,kka2_1:4_70,Kka2,kka2_1:4,P00552,0.554767,NO,70,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.017,-3.762,2.745,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.168804,0.00411884,0.554767 beta-lactamase_E35N,beta-lactamase_35,TEM-1,beta-lactamase,P62593,0.554775,NO,35,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-0.869,-3.445,2.576,5.10723,0.15,H,A,0.52,0.21,1.081,,46.85,HAA,-1.88667,0.221079,0.00174441,0.554775 beta-lactamase_2500_S57C,beta-lactamase_2500_57,TEM-1,beta-lactamase_2500,P62593,0.554817,NO,57,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.918,-4.926,3.008,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.361275,0.00492804,0.554817 kka2_1:4_L107A,kka2_1:4_107,Kka2,kka2_1:4,P00552,0.554886,NO,107,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.238,-3.204,1.966,,0.197,.,B,0.55,-1.1,0.398,,71.59,BHH,-2.143,0.168804,0.00561937,0.554886 kka2_1:2_G245Q,kka2_1:2_245,Kka2,kka2_1:2,P00552,0.554929,NO,245,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.812,-4.042,3.23,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.295029,0.00683899,0.554929 beta-lactamase_D161F,beta-lactamase_161,TEM-1,beta-lactamase,P62593,0.554995,NO,161,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.891,-4.316,3.425,5.12208,0.341,,A,0.23,-0.52,1.602,,61.19,HAB,-0.961333,0.221079,0.000897697,0.554995 beta-lactamase_2500_G226P,beta-lactamase_2500_226,TEM-1,beta-lactamase_2500,P62593,0.555012,NO,226,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.461,-3.96,2.499,,0.701,T,l,0.29,-0.25,5.086,,74.48,HOH,-1.42933,0.361275,0.00665294,0.555012 beta-lactamase_2500_N274A,beta-lactamase_2500_274,TEM-1,beta-lactamase_2500,P62593,0.555047,NO,274,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.361275,0.0110418,0.555047 kka2_1:4_S104D,kka2_1:4_104,Kka2,kka2_1:4,P00552,0.55505,NO,104,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.436,-2.848,1.412,,0.536,T,A,0.27,-1.11,0.357,,63.64,HPP,-1.91433,0.168804,0.00555207,0.55505 beta-lactamase_0_D161K,beta-lactamase_0_161,TEM-1,beta-lactamase_0,P62593,0.555123,NO,161,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.891,-3.426,2.535,,0.341,,A,0.75,-0.52,0.795,,61.19,HAB,-0.961333,0.0500837,0.000897697,0.555123 gb1_A252Q,gb1_252,gb1,gb1,P06654,0.555142,NO,252,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.175,-3.635,2.46,,,,,,,,,,PHA,-1.55967,0.177985,0.00125598,0.555142 Pab1_A158L,Pab1_158,Pab1,Pab1,P04147,0.55519,NO,158,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.154,-2.874,1.72,,,,,,,1.197,,56.33,HHP,-1.40733,0.175299,0.000649733,0.55519 beta-lactamase_2500_V101Y,beta-lactamase_2500_101,TEM-1,beta-lactamase_2500,P62593,0.555204,NO,101,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.295,-4.116,2.821,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.361275,0.00374492,0.555204 kka2_1:1_R253S,kka2_1:1_253,Kka2,kka2_1:1,P00552,0.555205,NO,253,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.356,-3.389,2.033,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.520039,0.0144195,0.555205 E1_Ubiquitin_H70N,E1_Ubiquitin_70,Uba1,E1_Ubiquitin,P0CG63,0.555261,NO,70,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-1.36,,,,0.05,E,B,0.61,-0.97,,,93.18,HBH,-1.146,0.18783,0.00206914,0.555261 kka2_1:1_L94T,kka2_1:1_94,Kka2,kka2_1:1,P00552,0.555295,NO,94,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.618,-2.787,1.169,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.520039,0.00520888,0.555295 kka2_1:1_L259P,kka2_1:1_259,Kka2,kka2_1:1,P00552,0.555367,NO,259,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.088,-4.066,2.978,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.520039,0.0206964,0.555367 beta-lactamase_E270P,beta-lactamase_270,TEM-1,beta-lactamase,P62593,0.55537,NO,270,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.723,-3.869,2.146,5.33196,0.422,H,A,0.52,1.15,1.745,,64.34,AAB,-1.70933,0.221079,0.00767762,0.55537 beta-lactamase_625_M184Q,beta-lactamase_625_184,TEM-1,beta-lactamase_625,P62593,0.555387,NO,184,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.593,-3.011,1.418,,,H,A,0.55,-0.87,2.765,,62.94,HHH,-1.41,0.213352,0.00356019,0.555387 kka2_1:1_M148T,kka2_1:1_148,Kka2,kka2_1:1,P00552,0.555406,NO,148,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.847,-2.724,0.877,,0.268,H,A,1.59,0.71,4.618,,64.39,BHA,-1.65467,0.520039,0.00982664,0.555406 beta-lactamase_2500_R159V,beta-lactamase_2500_159,TEM-1,beta-lactamase_2500,P62593,0.555422,NO,159,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-0.94,-3.779,2.839,,0.316,,B,1.2,-0.55,2.341,,64.34,PBH,-1.011,0.361275,0.00108472,0.555422 kka2_1:2_A144V,kka2_1:2_144,Kka2,kka2_1:2,P00552,0.555462,NO,144,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.859,-2.095,1.236,,,H,A,0.46,0.21,6.844,,52.65,BHB,-1.72933,0.295029,0.00231095,0.555462 beta-lactamase_0_S256D,beta-lactamase_0_256,TEM-1,beta-lactamase_0,P62593,0.555527,NO,256,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.0500837,0.00710634,0.555527 beta-lactamase_2500_E87S,beta-lactamase_2500_87,TEM-1,beta-lactamase_2500,P62593,0.555574,NO,87,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.421,-3.382,1.961,,0.048,,B,1.04,0.92,17.923,17.923,64.69,PAP,-1.969,0.361275,0.00337888,0.555574 kka2_1:2_D159H,kka2_1:2_159,Kka2,kka2_1:2,P00552,0.555586,NO,159,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.82,-4.547,3.727,,0.28,.,B,0.75,1.25,0.899,,48.11,HAA,-1.48333,0.295029,0.0030485,0.555586 kka2_1:1_D220H,kka2_1:1_220,Kka2,kka2_1:1,P00552,0.555603,NO,220,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.787,-4.544,3.757,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.520039,0.00158066,0.555603 beta-lactamase_2500_F228Q,beta-lactamase_2500_228,TEM-1,beta-lactamase_2500,P62593,0.555729,NO,228,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-2.342,-2.674,0.332,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.361275,0.0046669,0.555729 kka2_1:1_I246C,kka2_1:1_246,Kka2,kka2_1:1,P00552,0.555747,NO,246,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-2.008,-4.975,2.967,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.520039,0.0139479,0.555747 kka2_1:1_D227E,kka2_1:1_227,Kka2,kka2_1:1,P00552,0.555748,NO,227,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.758,-3.138,1.38,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.520039,0.00745029,0.555748 beta-lactamase_R63D,beta-lactamase_63,TEM-1,beta-lactamase,P62593,0.555758,NO,63,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-0.943,-3.762,2.819,5.49979,0.218,,B,0.45,-0.31,0.677,,44.06,ABH,-0.992333,0.221079,0.00126938,0.555758 kka2_1:2_A229M,kka2_1:2_229,Kka2,kka2_1:2,P00552,0.555802,NO,229,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.739,-4.743,3.004,,0.32,H,A,0.46,-0.7,6.549,,63.64,HHA,-1.851,0.295029,0.00942138,0.555802 beta-lactamase_L89R,beta-lactamase_89,TEM-1,beta-lactamase,P62593,0.555862,NO,89,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.096,-3.963,2.867,5.41092,0.168,T,A,1.75,0.63,1.599,,64.34,PHO,-1.75767,0.221079,0.00207068,0.555862 beta-lactamase_L167H,beta-lactamase_167,TEM-1,beta-lactamase,P62593,0.555913,NO,167,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.138,-4.852,3.714,5.13111,0.015,G,A,0.08,-0.63,0.4,,64.69,AHP,-1.30767,0.221079,0.00303566,0.555913 beta-lactamase_L47W,beta-lactamase_47,TEM-1,beta-lactamase,P62593,0.556003,NO,47,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.876,-5.24,3.364,5.27297,0.007,E,B,1.07,0.2,1.244,,67.83,AHA,-1.639,0.221079,0.00439844,0.556003 beta-lactamase_L135N,beta-lactamase_135,TEM-1,beta-lactamase,P62593,0.556092,NO,135,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.002,-4.152,3.15,5.28497,0.117,H,A,1.07,-0.58,0.697,,43.71,PHH,-1.03767,0.221079,0.00244423,0.556092 kka2_1:4_L126P,kka2_1:4_126,Kka2,kka2_1:4,P00552,0.5561,NO,126,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.246,-4.15,2.904,,0.285,S,B,0.55,0.12,0.302,,51.89,PHA,-1.744,0.168804,0.0066485,0.5561 kka2_1:8_F133L,kka2_1:8_133,Kka2,kka2_1:8,P00552,0.556116,NO,133,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-0.871,-2.98,2.109,,0.178,,B,1.62,0.43,1.816,,42.42,OHA,-0.871667,0.100394,0.00182168,0.556116 kka2_1:8_F133L,kka2_1:8_133,Kka2,kka2_1:8,P00552,0.556116,NO,133,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-0.871,-2.98,2.109,,0.178,,B,1.62,0.43,1.816,,42.42,OHA,-0.871667,0.100394,0.00182168,0.556116 kka2_1:2_F256S,kka2_1:2_256,Kka2,kka2_1:2,P00552,0.556123,NO,256,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.49,-3.766,2.276,,,H,A,0.58,-0.78,1.653,,53.03,HHH,-1.423,0.295029,0.0132841,0.556123 kka2_1:8_L170V,kka2_1:8_170,Kka2,kka2_1:8,P00552,0.556131,NO,170,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.28,-1.716,0.436,,0.029,H,A,1.59,0.11,1.453,,62.5,AHH,-1.534,0.100394,0.00730791,0.556131 kka2_1:8_L170V,kka2_1:8_170,Kka2,kka2_1:8,P00552,0.556131,NO,170,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.28,-1.716,0.436,,0.029,H,A,1.59,0.11,1.453,,62.5,AHH,-1.534,0.100394,0.00730791,0.556131 beta-lactamase_0_Q97K,beta-lactamase_0_97,TEM-1,beta-lactamase_0,P62593,0.556245,NO,97,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.072,-2.314,0.242,,0.823,G,A,0.64,2.42,16.954,16.954,77.62,PPP,-2.43833,0.0500837,0.0045116,0.556245 beta-lactamase_625_L191H,beta-lactamase_625_191,TEM-1,beta-lactamase_625,P62593,0.55625,NO,191,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.087,-4.898,3.811,,,H,A,0.55,0.09,1.908,,63.29,BHH,-1.445,0.213352,0.00263549,0.55625 beta-lactamase_2500_G216P,beta-lactamase_2500_216,TEM-1,beta-lactamase_2500,P62593,0.556309,NO,216,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.477,-3.898,2.421,,0.437,I,A,0.29,-0.58,1.983,,74.48,HOO,-1.68067,0.361275,0.00639568,0.556309 kka2_1:2_R239C,kka2_1:2_239,Kka2,kka2_1:2,P00552,0.556342,NO,239,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.949,-5.104,2.155,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.295029,0.00835326,0.556342 Ubiquitin_G10C,Ubiquitin_10,Uba1,Ubiquitin,P0CG48,0.556452,NO,10,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.396,-5.054,3.658,5.29806,0.115,S,l,,0.2,,,,POB,-1.38633,0.205827,0.000748953,0.556452 Ubiquitin_L67N,Ubiquitin_67,Uba1,Ubiquitin,P0CG48,0.556452,NO,67,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.435,-3.924,2.489,4.92156,,E,B,1.19,-1.02,6.371,6.371,30.8,PHB,-1.628,0.205827,0.000482727,0.556452 Ubiquitin_L8N,Ubiquitin_8,Uba1,Ubiquitin,P0CG48,0.556452,NO,8,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.723,-2.949,1.226,5.28016,0.664,T,A,0.08,-0.34,0.664,,29.05,PHP,-1.51567,0.205827,0.000726165,0.556452 Ubiquitin_R42N,Ubiquitin_42,Uba1,Ubiquitin,P0CG48,0.556452,NO,42,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.571,-3.631,2.06,5.07805,0.244,E,B,0.68,-0.54,1.976,,72.85,PBH,-1.38967,0.205827,0.000622265,0.556452 Ubiquitin_T12I,Ubiquitin_12,Uba1,Ubiquitin,P0CG48,0.556452,NO,12,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.288,-2.668,1.38,4.93973,0.417,E,B,0.8,0.12,2.762,,25.84,BPH,-1.39867,0.205827,0.000657544,0.556452 kka2_1:2_A34T,kka2_1:2_34,Kka2,kka2_1:2,P00552,0.55646,NO,34,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.928,-3.197,2.269,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.295029,0.00343484,0.55646 beta-lactamase_156_V31N,beta-lactamase_156_31,TEM-1,beta-lactamase_156,P62593,0.556468,NO,31,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.822,-4.194,2.372,,,H,A,0.44,-0.46,4.126,,73.78,BHB,-2.03767,0.111618,0.00478065,0.556468 beta-lactamase_Y95C,beta-lactamase_95,TEM-1,beta-lactamase,P62593,0.55651,NO,95,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-1.715,-4.95,3.235,5.67068,0.122,,b,0.96,-0.37,2.341,,77.62,BHP,-2.16167,0.221079,0.00479449,0.55651 PSD95pdz3_A376L,PSD95pdz3_376,PSD95pdz3,PSD95pdz3,P31016,0.556524,NO,376,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.307,-2.815,1.508,4.72134,,,,,17.108,,,,HHH,-1.49567,0.0758425,0.000341232,0.556524 kka2_1:2_E262Q,kka2_1:2_262,Kka2,kka2_1:2,P00552,0.556551,NO,262,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-0.829,-2.552,1.723,,0.059,G,A,1.04,-0.18,2.383,,42.42,AAH,-0.816,0.295029,0.0191586,0.556551 beta-lactamase_2500_I140A,beta-lactamase_2500_140,TEM-1,beta-lactamase_2500,P62593,0.556572,NO,140,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.733,-3.145,1.412,,0.128,H,A,0.48,0.41,1.628,,73.08,PHO,-1.48733,0.361275,0.00597777,0.556572 kka2_1:1_V16M,kka2_1:1_16,Kka2,kka2_1:1,P00552,0.556599,NO,16,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-3.087,-3.551,0.464,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.520039,0.00694011,0.556599 kka2_1:4_E262K,kka2_1:4_262,Kka2,kka2_1:4,P00552,0.556694,NO,262,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-0.829,-3.058,2.229,,0.059,G,A,1.04,-0.18,2.383,,42.42,AAH,-0.816,0.168804,0.0191586,0.556694 kka2_1:1_R38P,kka2_1:1_38,Kka2,kka2_1:1,P00552,0.556703,NO,38,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.207,-4.041,2.834,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.520039,0.00372499,0.556703 beta-lactamase_2500_G216F,beta-lactamase_2500_216,TEM-1,beta-lactamase_2500,P62593,0.556712,NO,216,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.477,-4.417,2.94,,0.437,I,A,0.29,-0.58,1.983,,74.48,HOO,-1.68067,0.361275,0.00639568,0.556712 kka2_1:1_L165F,kka2_1:1_165,Kka2,kka2_1:1,P00552,0.556743,NO,165,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-2.453,-4.3,1.847,,0.299,,B,1.59,1.12,2.47,,64.39,OHH,-1.90967,0.520039,0.00801161,0.556743 beta-lactamase_156_L160E,beta-lactamase_156_160,TEM-1,beta-lactamase_156,P62593,0.556807,NO,160,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.977,-3.906,2.929,,0.022,,B,0.55,-0.6,1.095,,44.41,BHA,-0.936,0.111618,0.00193775,0.556807 beta-lactamase_0_G154F,beta-lactamase_0_154,TEM-1,beta-lactamase_0,P62593,0.556811,NO,154,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.823,-4.328,3.505,,0.54,T,l,0.29,-0.56,3.629,,64.69,HOA,-1.635,0.0500837,0.00180205,0.556811 kka2_1:2_L184Y,kka2_1:2_184,Kka2,kka2_1:2,P00552,0.556846,NO,184,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.496,-4.144,2.648,,0.489,E,B,0.55,-0.06,14.044,14.044,63.26,AHH,-1.24833,0.295029,0.00518742,0.556846 beta-lactamase_2500_M127G,beta-lactamase_2500_127,TEM-1,beta-lactamase_2500,P62593,0.556917,NO,127,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-2.251,-3.785,1.534,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.361275,0.00437927,0.556917 kka2_1:2_V198T,kka2_1:2_198,Kka2,kka2_1:2,P00552,0.557011,NO,198,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.719,-2.237,0.518,,0.05,E,B,1.48,-0.95,1.074,,56.06,HHA,-1.88667,0.295029,0.00835002,0.557011 kka2_1:1_D90A,kka2_1:1_90,Kka2,kka2_1:1,P00552,0.557117,NO,90,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.459,-3.423,0.964,,0.104,E,B,0.75,0.73,6.085,,64.39,BAH,-1.72833,0.520039,0.00583842,0.557117 beta-lactamase_L219E,beta-lactamase_219,TEM-1,beta-lactamase,P62593,0.557119,NO,219,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.313,-3.999,2.686,5.74153,,I,A,0.84,-0.51,2.321,,74.48,HHB,-1.21533,0.221079,0.00664345,0.557119 kka2_1:2_L174P,kka2_1:2_174,Kka2,kka2_1:2,P00552,0.557167,NO,174,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.952,-4.115,3.163,,,H,A,1.59,-0.31,8.521,,51.89,BHB,-2.08533,0.295029,0.00438501,0.557167 beta-lactamase_2500_V72C,beta-lactamase_2500_72,TEM-1,beta-lactamase_2500,P62593,0.557218,NO,72,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.658,-4.8,3.142,,,H,A,0.44,-1.03,2.079,,65.73,BHH,-1.32167,0.361275,0.00501194,0.557218 beta-lactamase_L218P,beta-lactamase_218,TEM-1,beta-lactamase,P62593,0.557219,NO,218,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.391,-4.052,2.661,4.88972,,I,b,2.89,-0.53,12.788,12.788,74.48,OHH,-1.58867,0.221079,0.00618274,0.557219 beta-lactamase_2500_L38Q,beta-lactamase_2500_38,TEM-1,beta-lactamase_2500,P62593,0.557272,NO,38,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.343,-4.155,2.812,,0.088,H,A,0.55,0.2,2.71,,64.34,PHO,-1.78033,0.361275,0.00373244,0.557272 kka2_1:8_C131V,kka2_1:8_131,Kka2,kka2_1:8,P00552,0.55731,NO,131,C,V,CV,Special,Hydrophobic,5.07,5.60847,0.538465,192,121,117,-4,108.5,140,31.5,-0.831,-3.332,2.501,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.100394,0.00170814,0.55731 kka2_1:8_C131V,kka2_1:8_131,Kka2,kka2_1:8,P00552,0.55731,NO,131,C,V,CV,Special,Hydrophobic,5.07,5.60847,0.538465,192,121,117,-4,108.5,140,31.5,-0.831,-3.332,2.501,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.100394,0.00170814,0.55731 beta-lactamase_L282G,beta-lactamase_282,TEM-1,beta-lactamase,P62593,0.557348,NO,282,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.586,-3.803,2.217,5.16743,0.007,H,A,1.07,0.34,31.31,31.31,63.99,PHH,-1.82367,0.221079,0.0449821,0.557348 kka2_1:8_A237R,kka2_1:8_237,Kka2,kka2_1:8,P00552,0.557383,NO,237,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.12,-4.175,2.055,,0.068,H,A,0.46,-0.71,0.449,,92.05,HHA,-2.10433,0.100394,0.012257,0.557383 kka2_1:8_A237R,kka2_1:8_237,Kka2,kka2_1:8,P00552,0.557383,NO,237,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.12,-4.175,2.055,,0.068,H,A,0.46,-0.71,0.449,,92.05,HHA,-2.10433,0.100394,0.012257,0.557383 beta-lactamase_2500_G114K,beta-lactamase_2500_114,TEM-1,beta-lactamase_2500,P62593,0.557404,NO,114,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.094,-3.566,2.472,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.361275,0.00224919,0.557404 kka2_1:8_C209D,kka2_1:8_209,Kka2,kka2_1:8,P00552,0.557439,NO,209,C,D,CD,Special,negativeCharge,5.07,5.0516,-0.0184,154,121,133,12,108.5,111.1,2.6,-0.906,-3.991,3.085,,,,a,1.5,-0.89,0.391,,19.32,AOO,-0.903,0.100394,0.00260862,0.557439 kka2_1:8_C209D,kka2_1:8_209,Kka2,kka2_1:8,P00552,0.557439,NO,209,C,D,CD,Special,negativeCharge,5.07,5.0516,-0.0184,154,121,133,12,108.5,111.1,2.6,-0.906,-3.991,3.085,,,,a,1.5,-0.89,0.391,,19.32,AOO,-0.903,0.100394,0.00260862,0.557439 beta-lactamase_P65I,beta-lactamase_65,TEM-1,beta-lactamase,P62593,0.55745,NO,65,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.894,-3.716,2.822,5.59094,0.098,E,B,0.23,-0.62,0.623,,40.56,HOH,-1.03233,0.221079,0.00152776,0.55745 beta-lactamase_2500_I45S,beta-lactamase_2500_45,TEM-1,beta-lactamase_2500,P62593,0.557666,NO,45,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-2.421,-2.717,0.296,,,E,B,0.48,-0.3,3.793,,77.62,HHA,-2.30267,0.361275,0.00452842,0.557666 kka2_1:4_R66A,kka2_1:4_66,Kka2,kka2_1:4,P00552,0.557675,NO,66,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-0.922,-3.14,2.218,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.168804,0.00161025,0.557675 gb1_A249K,gb1_249,gb1,gb1,P06654,0.557676,NO,249,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.739,-3.391,1.652,,,,,,,0.252,,44.87,AHH,-1.67367,0.177985,0.00333585,0.557676 gb1_N263D,gb1_263,gb1,gb1,P06654,0.557676,NO,263,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-1.162,-2.796,1.634,,,,,,,,,,APO,-2.04233,0.177985,0.0035297,0.557676 kka2_1:1_A117V,kka2_1:1_117,Kka2,kka2_1:1,P00552,0.557726,NO,117,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.828,-2.25,1.422,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.520039,0.00282984,0.557726 beta-lactamase_0_G76P,beta-lactamase_0_76,TEM-1,beta-lactamase_0,P62593,0.557808,NO,76,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.189,-3.852,2.663,,,H,A,0.29,-0.67,1.188,,67.83,OOH,-1.22267,0.0500837,0.00476637,0.557808 beta-lactamase_D174I,beta-lactamase_174,TEM-1,beta-lactamase,P62593,0.557833,NO,174,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.738,-4.01,3.272,5.44133,0.238,,B,1.22,-0.1,,,,PAA,-1.91233,0.221079,0.00125633,0.557833 Pab1_F149A,Pab1_149,Pab1,Pab1,P04147,0.557894,NO,149,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.149,-3.12,1.971,,0.183,T,A,1.33,1.09,,,,HHO,-1.27767,0.175299,0.000325688,0.557894 kka2_1:2_A79Y,kka2_1:2_79,Kka2,kka2_1:2,P00552,0.557899,NO,79,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.368,-4.411,2.043,,0.563,.,B,0.46,-0.43,0.475,,71.59,HHH,-1.752,0.295029,0.00664821,0.557899 kka2_1:4_V185E,kka2_1:4_185,Kka2,kka2_1:4,P00552,0.558014,NO,185,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.045,-3.799,2.754,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.168804,0.00367031,0.558014 beta-lactamase_L49E,beta-lactamase_49,TEM-1,beta-lactamase,P62593,0.558081,NO,49,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.897,-3.608,1.711,5.86005,0.131,T,A,1.3,0.04,3.112,,64.69,AHP,-1.99233,0.221079,0.00401477,0.558081 beta-lactamase_625_T187K,beta-lactamase_625_187,TEM-1,beta-lactamase_625,P62593,0.558154,NO,187,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.401,-3.578,2.177,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.213352,0.00491782,0.558154 Pab1_F173H,Pab1_173,Pab1,Pab1,P04147,0.558234,NO,173,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.477,-3.987,2.51,,,E,B,0.87,-0.16,1.636,,63.26,BHA,-1.36967,0.175299,0.00148779,0.558234 beta-lactamase_2500_T264D,beta-lactamase_2500_264,TEM-1,beta-lactamase_2500,P62593,0.558237,NO,264,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.361275,0.0119399,0.558237 kka2_1:2_D216V,kka2_1:2_216,Kka2,kka2_1:2,P00552,0.558319,NO,216,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.785,-3.805,3.02,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.295029,0.00229969,0.558319 kka2_1:2_E235W,kka2_1:2_235,Kka2,kka2_1:2,P00552,0.55836,NO,235,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.955,-5.585,3.63,,0.631,H,A,1.04,0.12,26.048,26.048,65.53,OAH,-2.07267,0.295029,0.0102806,0.55836 kka2_1:2_P179S,kka2_1:2_179,Kka2,kka2_1:2,P00552,0.558361,NO,179,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.974,-2.711,1.737,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.295029,0.00298346,0.558361 beta-lactamase_625_T131N,beta-lactamase_625_131,TEM-1,beta-lactamase_625,P62593,0.558365,NO,131,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.328,-3.603,2.275,,,H,A,0.22,-0.69,2.031,,67.48,PPH,-1.00867,0.213352,0.00345886,0.558365 beta-lactamase_2500_E62N,beta-lactamase_2500_62,TEM-1,beta-lactamase_2500,P62593,0.558472,NO,62,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.193,-3.541,2.348,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.361275,0.00264802,0.558472 kka2_1:4_G210T,kka2_1:4_210,Kka2,kka2_1:4,P00552,0.558563,NO,210,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.095,-3.513,2.418,,0.103,T,A,0.29,-0.62,0.271,,50,OOB,-0.966667,0.168804,0.00598378,0.558563 kka2_1:8_K112F,kka2_1:8_112,Kka2,kka2_1:8,P00552,0.558584,NO,112,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-2.491,-4.227,1.736,,0.076,H,A,1.3,-1.37,10.58,10.58,56.06,ABH,-2.00133,0.100394,0.00645389,0.558584 kka2_1:8_K112F,kka2_1:8_112,Kka2,kka2_1:8,P00552,0.558584,NO,112,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-2.491,-4.227,1.736,,0.076,H,A,1.3,-1.37,10.58,10.58,56.06,ABH,-2.00133,0.100394,0.00645389,0.558584 kka2_1:1_T187N,kka2_1:1_187,Kka2,kka2_1:1,P00552,0.5586,NO,187,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.273,-3.75,2.477,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.520039,0.00693073,0.5586 kka2_1:8_D190E,kka2_1:8_190,Kka2,kka2_1:8,P00552,0.558646,NO,190,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.708,-2.793,2.085,,0.213,S,b,0.29,-0.82,,,,OAH,-0.711667,0.100394,0.00247989,0.558646 kka2_1:8_D190E,kka2_1:8_190,Kka2,kka2_1:8,P00552,0.558646,NO,190,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.708,-2.793,2.085,,0.213,S,b,0.29,-0.82,,,,OAH,-0.711667,0.100394,0.00247989,0.558646 beta-lactamase_L219N,beta-lactamase_219,TEM-1,beta-lactamase,P62593,0.558681,NO,219,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.313,-4.217,2.904,5.74153,,I,A,0.84,-0.51,2.321,,74.48,HHB,-1.21533,0.221079,0.00664345,0.558681 kka2_1:1_S114C,kka2_1:1_114,Kka2,kka2_1:1,P00552,0.558777,NO,114,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.527,-5.142,2.615,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.520039,0.00705262,0.558777 beta-lactamase_E195I,beta-lactamase_195,TEM-1,beta-lactamase,P62593,0.558819,NO,195,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.186,-4.191,2.005,7.28489,1.016,S,A,1.52,0.85,2.583,,77.62,OAH,-2.02,0.221079,0.00496565,0.558819 kka2_1:2_R121H,kka2_1:2_121,Kka2,kka2_1:2,P00552,0.558828,NO,121,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.552,-2.742,1.19,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.295029,0.00523326,0.558828 beta-lactamase_S104R,beta-lactamase_104,TEM-1,beta-lactamase,P62593,0.559028,NO,104,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.015,-3.804,2.789,4.92365,0.04,,b,0.82,0.57,4.02,,63.29,HPO,-1.05267,0.221079,0.00218083,0.559028 beta-lactamase_156_Y95Q,beta-lactamase_156_95,TEM-1,beta-lactamase_156,P62593,0.559085,NO,95,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-1.715,-4.267,2.552,,0.122,,b,0.21,-0.37,2.341,,77.62,BHP,-2.16167,0.111618,0.00479449,0.559085 kka2_1:2_Q27A,kka2_1:2_27,Kka2,kka2_1:2,P00552,0.55909,NO,27,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-1.659,-3.31,1.651,,0.608,.,A,0.64,0.71,0.521,,65.53,PPP,-1.90733,0.295029,0.00595365,0.55909 kka2_1:1_F240R,kka2_1:1_240,Kka2,kka2_1:1,P00552,0.559109,NO,240,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-0.911,-4.185,3.274,,,H,A,1.62,-1.21,5.798,,50.38,BHH,-1.67267,0.520039,0.00552543,0.559109 kka2_1:1_E160R,kka2_1:1_160,Kka2,kka2_1:1,P00552,0.559135,NO,160,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.683,-3.847,2.164,,0.989,G,A,1.04,2.28,0.273,,71.59,AAA,-1.36133,0.520039,0.00935762,0.559135 beta-lactamase_625_T69P,beta-lactamase_625_69,TEM-1,beta-lactamase_625,P62593,0.559149,NO,69,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-0.973,-3.715,2.742,,,G,A,0.22,-1.24,2.716,,93.01,PPH,-1.01833,0.213352,0.00127498,0.559149 kka2_1:8_V153R,kka2_1:8_153,Kka2,kka2_1:8,P00552,0.55915,NO,153,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.092,-4.22,3.128,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.100394,0.00501119,0.55915 kka2_1:8_V153R,kka2_1:8_153,Kka2,kka2_1:8,P00552,0.55915,NO,153,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.092,-4.22,3.128,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.100394,0.00501119,0.55915 beta-lactamase_D83M,beta-lactamase_83,TEM-1,beta-lactamase,P62593,0.559202,NO,83,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.066,-4.912,3.846,5.40616,0.354,H,A,1.33,0.22,0.861,,48.95,HAH,-1.34733,0.221079,0.00205968,0.559202 beta-lactamase_39_F70D,beta-lactamase_39_70,TEM-1,beta-lactamase_39,P62593,0.559238,NO,70,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.169,-3.91,2.741,,,H,A,0.58,-1.34,1.14,,63.99,PHB,-0.980667,0.0495842,0.00193499,0.559238 kka2_1:8_W15S,kka2_1:8_15,Kka2,kka2_1:8,P00552,0.559276,NO,15,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-1.392,-3.829,2.437,,0.01,G,A,1.51,0.15,0.827,,52.27,HHH,-2.10533,0.100394,0.00585505,0.559276 kka2_1:8_W15S,kka2_1:8_15,Kka2,kka2_1:8,P00552,0.559276,NO,15,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-1.392,-3.829,2.437,,0.01,G,A,1.51,0.15,0.827,,52.27,HHH,-2.10533,0.100394,0.00585505,0.559276 beta-lactamase_A245L,beta-lactamase_245,TEM-1,beta-lactamase,P62593,0.559284,NO,245,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.068,-3.266,2.198,4.78972,,E,B,0.17,-0.92,0.831,,64.69,HHH,-1.58133,0.221079,0.00391032,0.559284 kka2_1:1_D90G,kka2_1:1_90,Kka2,kka2_1:1,P00552,0.559332,NO,90,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.459,-3.503,1.044,,0.104,E,B,0.75,0.73,6.085,,64.39,BAH,-1.72833,0.520039,0.00583842,0.559332 kka2_1:4_A137D,kka2_1:4_137,Kka2,kka2_1:4,P00552,0.559393,NO,137,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.156,-4.088,1.932,,0.029,H,A,0.46,0.34,2.227,,63.26,PHB,-2.559,0.168804,0.00515054,0.559393 kka2_1:2_L81N,kka2_1:2_81,Kka2,kka2_1:2,P00552,0.559399,NO,81,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.427,-4.237,2.81,,0.46,E,A,1.59,-0.14,1.895,,63.64,HHA,-1.50567,0.295029,0.00805839,0.559399 beta-lactamase_625_R257A,beta-lactamase_625_257,TEM-1,beta-lactamase_625,P62593,0.559443,NO,257,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.213352,0.00756629,0.559443 beta-lactamase_P143F,beta-lactamase_143,TEM-1,beta-lactamase,P62593,0.55945,NO,143,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.967,-4.308,3.341,5.16366,0.075,H,A,0.99,-0.37,0.479,,66.78,OOB,-1.354,0.221079,0.00114551,0.55945 kka2_1:2_P98D,kka2_1:2_98,Kka2,kka2_1:2,P00552,0.559582,NO,98,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.526,-2.576,1.05,,0.391,S,B,0.52,-0.65,2.82,,63.26,HOO,-1.19167,0.295029,0.00622754,0.559582 kka2_1:4_V214A,kka2_1:4_214,Kka2,kka2_1:4,P00552,0.559584,NO,214,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.261,-3.113,1.852,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.168804,0.00692782,0.559584 kka2_1:1_G181Y,kka2_1:1_181,Kka2,kka2_1:1,P00552,0.559625,NO,181,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-2.698,-3.473,0.775,,0.379,S,B,0.75,0.78,15.356,15.356,71.59,AOA,-2.21,0.520039,0.00728319,0.559625 beta-lactamase_2500_I285S,beta-lactamase_2500_285,TEM-1,beta-lactamase_2500,P62593,0.559629,NO,285,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.361275,0.101555,0.559629 kka2_1:2_V186Q,kka2_1:2_186,Kka2,kka2_1:2,P00552,0.559655,NO,186,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.011,-4.284,3.273,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.295029,0.00409703,0.559655 beta-lactamase_T147P,beta-lactamase_147,TEM-1,beta-lactamase,P62593,0.559703,NO,147,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.149,-3.818,2.669,5.37474,0.281,H,A,0.8,-0.68,2.838,,64.34,HPH,-1.456,0.221079,0.00226017,0.559703 beta-lactamase_N168R,beta-lactamase_168,TEM-1,beta-lactamase,P62593,0.559704,NO,168,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-1.029,-3.58,2.551,5.42128,0.113,G,A,0.09,-0.4,1.211,,44.41,HPA,-1.13233,0.221079,0.00288667,0.559704 kka2_1:2_R177P,kka2_1:2_177,Kka2,kka2_1:2,P00552,0.559753,NO,177,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.282,-4.106,1.824,,0.521,T,A,1.2,0.16,1.842,,63.64,HBH,-2.36967,0.295029,0.00768224,0.559753 kka2_1:2_A110K,kka2_1:2_110,Kka2,kka2_1:2,P00552,0.559774,NO,110,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.064,-3.119,1.055,,0.175,H,A,0.46,-1.19,23.237,23.237,71.59,OHA,-1.91867,0.295029,0.00759851,0.559774 beta-lactamase_2500_V106N,beta-lactamase_2500_106,TEM-1,beta-lactamase_2500,P62593,0.559777,NO,106,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.218,-4.217,2.999,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.361275,0.00304168,0.559777 kka2_1:1_H188R,kka2_1:1_188,Kka2,kka2_1:1,P00552,0.559777,NO,188,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-0.913,-3.509,2.596,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.520039,0.00273139,0.559777 beta-lactamase_R255S,beta-lactamase_255,TEM-1,beta-lactamase,P62593,0.559823,NO,255,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.266,-3.703,1.437,5.55882,0.141,E,B,0.68,0.38,1.199,,63.99,PBH,-2.00433,0.221079,0.00499612,0.559823 kka2_1:8_L126G,kka2_1:8_126,Kka2,kka2_1:8,P00552,0.559878,NO,126,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.246,-3.853,2.607,,0.285,S,B,1.59,0.12,4.443,,51.89,PHA,-1.744,0.100394,0.0066485,0.559878 kka2_1:8_L126G,kka2_1:8_126,Kka2,kka2_1:8,P00552,0.559878,NO,126,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.246,-3.853,2.607,,0.285,S,B,1.59,0.12,4.443,,51.89,PHA,-1.744,0.100394,0.0066485,0.559878 kka2_1:4_L126Q,kka2_1:4_126,Kka2,kka2_1:4,P00552,0.559892,NO,126,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.246,-3.15,1.904,,0.285,S,B,0.55,0.12,0.302,,51.89,PHA,-1.744,0.168804,0.0066485,0.559892 beta-lactamase_0_A123T,beta-lactamase_0_123,TEM-1,beta-lactamase_0,P62593,0.55997,NO,123,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.834,-3.222,2.388,,0.039,H,A,0.46,-0.72,1.308,,41.26,PHH,-1.47367,0.0500837,0.0010157,0.55997 beta-lactamase_M115Y,beta-lactamase_115,TEM-1,beta-lactamase,P62593,0.560041,NO,115,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.389,-3.961,2.572,4.89743,0.019,E,B,1.3,0.08,1.236,,69.58,OHP,-1.25433,0.221079,0.0034337,0.560041 beta-lactamase_625_R59Y,beta-lactamase_625_59,TEM-1,beta-lactamase_625,P62593,0.560105,NO,59,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.345,-4.267,2.922,,0.329,S,L,1.2,-0.09,2.995,,73.08,HBO,-2.24267,0.213352,0.00318082,0.560105 kka2_1:4_Q136W,kka2_1:4_136,Kka2,kka2_1:4,P00552,0.56026,NO,136,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-3.021,-5.446,2.425,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.168804,0.00624149,0.56026 beta-lactamase_E35T,beta-lactamase_35,TEM-1,beta-lactamase,P62593,0.560267,NO,35,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-0.869,-3.447,2.578,5.10723,0.15,H,A,0.52,0.21,1.081,,46.85,HAA,-1.88667,0.221079,0.00174441,0.560267 beta-lactamase_L219A,beta-lactamase_219,TEM-1,beta-lactamase,P62593,0.56029,NO,219,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.313,-3.187,1.874,5.74153,,I,A,0.84,-0.51,2.321,,74.48,HHB,-1.21533,0.221079,0.00664345,0.56029 kka2_1:2_D156P,kka2_1:2_156,Kka2,kka2_1:2,P00552,0.56033,NO,156,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.696,-3.904,2.208,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.295029,0.00926998,0.56033 beta-lactamase_156_P65E,beta-lactamase_156_65,TEM-1,beta-lactamase_156,P62593,0.560342,NO,65,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.894,-3.524,2.63,,0.098,E,B,0.52,-0.62,0.623,,40.56,HOH,-1.03233,0.111618,0.00152776,0.560342 beta-lactamase_2500_G52E,beta-lactamase_2500_52,TEM-1,beta-lactamase_2500,P62593,0.560383,NO,52,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.149,-3.424,2.275,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.361275,0.00340138,0.560383 kka2_1:1_P76T,kka2_1:1_76,Kka2,kka2_1:1,P00552,0.56039,NO,76,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.449,-2.904,1.455,,0.331,.,B,0.52,-0.41,0.345,,63.64,HOO,-1.662,0.520039,0.00625685,0.56039 beta-lactamase_I93W,beta-lactamase_93,TEM-1,beta-lactamase,P62593,0.560433,NO,93,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.401,-5.418,4.017,5.74695,0.128,E,B,0.77,0.44,1.757,,67.83,BHB,-1.873,0.221079,0.00527066,0.560433 beta-lactamase_39_L136E,beta-lactamase_39_136,TEM-1,beta-lactamase_39,P62593,0.560574,NO,136,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.232,-3.938,2.706,,,H,A,0.55,-0.34,0.336,,48.95,HHH,-1.088,0.0495842,0.00442304,0.560574 kka2_1:4_L193Q,kka2_1:4_193,Kka2,kka2_1:4,P00552,0.560577,NO,193,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.983,-2.972,1.989,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.168804,0.00480179,0.560577 beta-lactamase_L47H,beta-lactamase_47,TEM-1,beta-lactamase,P62593,0.560596,NO,47,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.876,-2.811,0.935,5.27297,0.007,E,B,1.07,0.2,1.244,,67.83,AHA,-1.639,0.221079,0.00439844,0.560596 kka2_1:8_G245T,kka2_1:8_245,Kka2,kka2_1:8,P00552,0.560673,NO,245,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.812,-3.629,2.817,,0.655,T,g,0.75,0.03,1.148,,65.53,HOH,-1.19833,0.100394,0.00683899,0.560673 kka2_1:8_G245T,kka2_1:8_245,Kka2,kka2_1:8,P00552,0.560673,NO,245,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.812,-3.629,2.817,,0.655,T,g,0.75,0.03,1.148,,65.53,HOH,-1.19833,0.100394,0.00683899,0.560673 beta-lactamase_625_V117A,beta-lactamase_625_117,TEM-1,beta-lactamase_625,P62593,0.560686,NO,117,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.53,-3.142,1.612,,,H,A,0.44,-0.34,1.23,,65.03,PHB,-1.741,0.213352,0.00467906,0.560686 kka2_1:8_W69D,kka2_1:8_69,Kka2,kka2_1:8,P00552,0.560719,NO,69,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-0.859,-4.17,3.311,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.100394,0.0012874,0.560719 kka2_1:8_W69D,kka2_1:8_69,Kka2,kka2_1:8,P00552,0.560719,NO,69,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-0.859,-4.17,3.311,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.100394,0.0012874,0.560719 kka2_1:2_L107V,kka2_1:2_107,Kka2,kka2_1:2,P00552,0.560738,NO,107,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.238,-2.216,0.978,,0.197,,B,1.59,-1.1,2.68,,71.59,BHH,-2.143,0.295029,0.00561937,0.560738 beta-lactamase_2500_D99F,beta-lactamase_2500_99,TEM-1,beta-lactamase_2500,P62593,0.560739,NO,99,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.191,-4.277,3.086,,0.402,G,A,0.75,0.36,1.318,,64.69,PAH,-1.794,0.361275,0.00305446,0.560739 beta-lactamase_2500_L28G,beta-lactamase_2500_28,TEM-1,beta-lactamase_2500,P62593,0.560743,NO,28,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.579,-3.602,2.023,,0.277,H,A,0.55,-0.16,2.716,,93.01,PHH,-2.11333,0.361275,0.00359321,0.560743 kka2_1:8_A78Q,kka2_1:8_78,Kka2,kka2_1:8,P00552,0.560782,NO,78,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.744,-3.972,2.228,,0.078,,B,1.04,-0.53,1.251,,56.06,OHH,-1.863,0.100394,0.00457299,0.560782 kka2_1:8_A78Q,kka2_1:8_78,Kka2,kka2_1:8,P00552,0.560782,NO,78,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.744,-3.972,2.228,,0.078,,B,1.04,-0.53,1.251,,56.06,OHH,-1.863,0.100394,0.00457299,0.560782 beta-lactamase_625_G114T,beta-lactamase_625_114,TEM-1,beta-lactamase_625,P62593,0.56082,NO,114,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.094,-2.276,1.182,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.213352,0.00224919,0.56082 beta-lactamase_39_Y262K,beta-lactamase_39_262,TEM-1,beta-lactamase_39,P62593,0.560911,NO,262,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.0495842,0.00853516,0.560911 kka2_1:1_H188Y,kka2_1:1_188,Kka2,kka2_1:1,P00552,0.560981,NO,188,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-0.913,-3.365,2.452,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.520039,0.00273139,0.560981 beta-lactamase_39_G240P,beta-lactamase_39_240,TEM-1,beta-lactamase_39,P62593,0.561064,NO,240,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.0495842,0.00591201,0.561064 kka2_1:8_V185G,kka2_1:8_185,Kka2,kka2_1:8,P00552,0.561095,NO,185,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.045,-3.615,2.57,,0.058,E,B,1.48,-0.49,1.234,,46.97,HHH,-1.184,0.100394,0.00367031,0.561095 kka2_1:8_V185G,kka2_1:8_185,Kka2,kka2_1:8,P00552,0.561095,NO,185,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.045,-3.615,2.57,,0.058,E,B,1.48,-0.49,1.234,,46.97,HHH,-1.184,0.100394,0.00367031,0.561095 beta-lactamase_625_L135R,beta-lactamase_625_135,TEM-1,beta-lactamase_625,P62593,0.561112,NO,135,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.002,-4.002,3,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.213352,0.00244423,0.561112 beta-lactamase_2500_R63E,beta-lactamase_2500_63,TEM-1,beta-lactamase_2500,P62593,0.56127,NO,63,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-0.943,-3.298,2.355,,0.218,,B,1.2,-0.31,0.929,,44.06,ABH,-0.992333,0.361275,0.00126938,0.56127 kka2_1:8_L223K,kka2_1:8_223,Kka2,kka2_1:8,P00552,0.561337,NO,223,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.861,-3.793,2.932,,,H,A,1.59,-1.24,1.017,,50,HHH,-0.854333,0.100394,0.00253574,0.561337 kka2_1:8_L223K,kka2_1:8_223,Kka2,kka2_1:8,P00552,0.561337,NO,223,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.861,-3.793,2.932,,,H,A,1.59,-1.24,1.017,,50,HHH,-0.854333,0.100394,0.00253574,0.561337 beta-lactamase_0_P143I,beta-lactamase_0_143,TEM-1,beta-lactamase_0,P62593,0.561387,NO,143,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.967,-2.787,1.82,,0.075,H,A,0.52,-0.37,11.868,11.868,66.78,OOB,-1.354,0.0500837,0.00114551,0.561387 kka2_1:4_D216E,kka2_1:4_216,Kka2,kka2_1:4,P00552,0.561425,NO,216,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.785,-2.854,2.069,,0.018,E,B,0.75,-0.51,0.112,,19.32,HAB,-0.970333,0.168804,0.00229969,0.561425 kka2_1:1_Y22H,kka2_1:1_22,Kka2,kka2_1:1,P00552,0.561443,NO,22,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-1.583,-2.746,1.163,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.520039,0.00598977,0.561443 kka2_1:4_V186Q,kka2_1:4_186,Kka2,kka2_1:4,P00552,0.561463,NO,186,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.011,-4.284,3.273,,,E,B,0.44,-0.61,0.679,,45.83,HHP,-1.10967,0.168804,0.00409703,0.561463 kka2_1:4_F133S,kka2_1:4_133,Kka2,kka2_1:4,P00552,0.561464,NO,133,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-0.871,-3.662,2.791,,0.178,.,B,0.58,0.43,0.786,,42.42,OHA,-0.871667,0.168804,0.00182168,0.561464 beta-lactamase_625_N274V,beta-lactamase_625_274,TEM-1,beta-lactamase_625,P62593,0.561571,NO,274,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.213352,0.0110418,0.561571 kka2_1:1_D23S,kka2_1:1_23,Kka2,kka2_1:1,P00552,0.561575,NO,23,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.459,-2.448,-0.011,,0.695,E,B,0.75,-0.65,2.655,,65.53,HAH,-1.94033,0.520039,0.007195,0.561575 beta-lactamase_625_L284E,beta-lactamase_625_284,TEM-1,beta-lactamase_625,P62593,0.561593,NO,284,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.213352,0.0686156,0.561593 kka2_1:2_E86F,kka2_1:2_86,Kka2,kka2_1:2,P00552,0.561658,NO,86,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.86,-4.247,2.387,,0.369,.,B,1.04,1.92,3.573,,63.26,PAH,-1.98067,0.295029,0.00642858,0.561658 kka2_1:8_A222Y,kka2_1:8_222,Kka2,kka2_1:8,P00552,0.561696,NO,222,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.725,-4.191,3.466,,,H,A,1.04,-1.21,,,,HHH,-1.10833,0.100394,0.00207657,0.561696 kka2_1:8_A222Y,kka2_1:8_222,Kka2,kka2_1:8,P00552,0.561696,NO,222,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.725,-4.191,3.466,,,H,A,1.04,-1.21,,,,HHH,-1.10833,0.100394,0.00207657,0.561696 beta-lactamase_A185T,beta-lactamase_185,TEM-1,beta-lactamase,P62593,0.561741,NO,185,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.406,-2.128,0.722,4.89877,,H,A,2.34,-1.02,2.999,,65.03,HHP,-1.84033,0.221079,0.00467449,0.561741 kka2_1:8_R122P,kka2_1:8_122,Kka2,kka2_1:8,P00552,0.561857,NO,122,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.175,-3.279,1.104,,0.487,H,A,1.2,0.26,22.675,22.675,71.59,BBH,-1.53833,0.100394,0.00736512,0.561857 kka2_1:8_R122P,kka2_1:8_122,Kka2,kka2_1:8,P00552,0.561857,NO,122,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.175,-3.279,1.104,,0.487,H,A,1.2,0.26,22.675,22.675,71.59,BBH,-1.53833,0.100394,0.00736512,0.561857 beta-lactamase_39_I245H,beta-lactamase_39_245,TEM-1,beta-lactamase_39,P62593,0.562061,NO,245,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.0495842,0.00391032,0.562061 kka2_1:2_S204V,kka2_1:2_204,Kka2,kka2_1:2,P00552,0.562203,NO,204,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.353,-3.451,2.098,,0.144,E,A,0.27,-1.2,2.442,,65.53,HPO,-0.953333,0.295029,0.00881794,0.562203 beta-lactamase_0_L136Q,beta-lactamase_0_136,TEM-1,beta-lactamase_0,P62593,0.562217,NO,136,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.232,-4.242,3.01,,,H,A,0.55,-0.34,0.648,,48.95,HHH,-1.088,0.0500837,0.00442304,0.562217 beta-lactamase_156_L120N,beta-lactamase_156_120,TEM-1,beta-lactamase_156,P62593,0.56222,NO,120,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.044,-4.027,2.983,,,H,A,0.55,-1.13,7.813,,64.69,AHO,-1.13633,0.111618,0.00143563,0.56222 beta-lactamase_2500_P165K,beta-lactamase_2500_165,TEM-1,beta-lactamase_2500,P62593,0.562289,NO,165,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.373,-3.528,2.155,,0.203,T,A,0.52,-0.31,0.414,,73.78,AOA,-1.359,0.361275,0.00549538,0.562289 beta-lactamase_156_T178K,beta-lactamase_156_178,TEM-1,beta-lactamase_156,P62593,0.562295,NO,178,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-0.791,-3.457,2.666,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.111618,0.000684366,0.562295 beta-lactamase_156_T27Y,beta-lactamase_156_27,TEM-1,beta-lactamase_156,P62593,0.562311,NO,27,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.905,-4.144,2.239,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.111618,0.00306559,0.562311 beta-lactamase_2500_A278I,beta-lactamase_2500_278,TEM-1,beta-lactamase_2500,P62593,0.562331,NO,278,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.348,-3.123,1.775,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.361275,0.0310297,0.562331 kka2_1:4_D190A,kka2_1:4_190,Kka2,kka2_1:4,P00552,0.562498,NO,190,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.708,-3.331,2.623,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.168804,0.00247989,0.562498 kka2_1:8_A119R,kka2_1:8_119,Kka2,kka2_1:8,P00552,0.562516,NO,119,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.073,-3.886,2.813,,0.019,H,A,0.46,-0.57,1.511,,71.59,AHH,-2.34,0.100394,0.00441074,0.562516 kka2_1:8_A119R,kka2_1:8_119,Kka2,kka2_1:8,P00552,0.562516,NO,119,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.073,-3.886,2.813,,0.019,H,A,0.46,-0.57,1.511,,71.59,AHH,-2.34,0.100394,0.00441074,0.562516 kka2_1:1_V185L,kka2_1:1_185,Kka2,kka2_1:1,P00552,0.562592,NO,185,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.045,-2.834,1.789,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.520039,0.00367031,0.562592 kka2_1:1_Q136E,kka2_1:1_136,Kka2,kka2_1:1,P00552,0.562597,NO,136,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-3.021,-3.472,0.451,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.520039,0.00624149,0.562597 Pab1_K131Y,Pab1_131,Pab1,Pab1,P04147,0.562623,NO,131,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.083,-3.98,2.897,,0.462,E,B,1.82,0.57,,,,HBP,-1.12467,0.175299,0.000349395,0.562623 beta-lactamase_156_L136S,beta-lactamase_156_136,TEM-1,beta-lactamase_156,P62593,0.5627,NO,136,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.232,-3.705,2.473,,,H,A,0.55,-0.34,1.04,,48.95,HHH,-1.088,0.111618,0.00442304,0.5627 Pab1_K131W,Pab1_131,Pab1,Pab1,P04147,0.562714,NO,131,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.083,-5.14,4.057,,0.462,E,B,1.82,0.57,,,,HBP,-1.12467,0.175299,0.000349395,0.562714 kka2_1:8_L126H,kka2_1:8_126,Kka2,kka2_1:8,P00552,0.562717,NO,126,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.246,-4.997,3.751,,0.285,S,B,1.59,0.12,4.443,,51.89,PHA,-1.744,0.100394,0.0066485,0.562717 kka2_1:8_L126H,kka2_1:8_126,Kka2,kka2_1:8,P00552,0.562717,NO,126,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.246,-4.997,3.751,,0.285,S,B,1.59,0.12,4.443,,51.89,PHA,-1.744,0.100394,0.0066485,0.562717 beta-lactamase_A235C,beta-lactamase_235,TEM-1,beta-lactamase,P62593,0.562728,NO,235,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.266,-4.693,3.427,4.83024,0.32,E,B,0.52,-0.86,1.344,,50,OHO,-0.89,0.221079,0.00493474,0.562728 kka2_1:4_L223R,kka2_1:4_223,Kka2,kka2_1:4,P00552,0.562765,NO,223,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.861,-4.044,3.183,,,H,A,1.59,-1.24,1.268,,50,HHH,-0.854333,0.168804,0.00253574,0.562765 beta-lactamase_0_R118K,beta-lactamase_0_118,TEM-1,beta-lactamase_0,P62593,0.562814,NO,118,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.413,-3.492,1.079,,0.457,H,A,1.2,1.39,3.961,,77.62,HBA,-1.785,0.0500837,0.00538794,0.562814 beta-lactamase_625_A124N,beta-lactamase_625_124,TEM-1,beta-lactamase_625,P62593,0.562843,NO,124,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.181,-3.812,2.631,,,H,A,0.46,-0.9,2.027,,64.34,HHH,-1.152,0.213352,0.00481399,0.562843 kka2_1:1_D33H,kka2_1:1_33,Kka2,kka2_1:1,P00552,0.562849,NO,33,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.186,-4.719,2.533,,0.561,S,A,0.75,3.35,2.568,,71.59,PAH,-1.306,0.520039,0.00633568,0.562849 beta-lactamase_E35R,beta-lactamase_35,TEM-1,beta-lactamase,P62593,0.562897,NO,35,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-0.869,-3.551,2.682,5.10723,0.15,H,A,0.52,0.21,1.081,,46.85,HAA,-1.88667,0.221079,0.00174441,0.562897 kka2_1:1_F20D,kka2_1:1_20,Kka2,kka2_1:1,P00552,0.562908,NO,20,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-3.354,-3.734,0.38,,0.935,T,B,0.58,-0.41,1.657,,92.05,HHO,-1.992,0.520039,0.00701744,0.562908 kka2_1:2_T28R,kka2_1:2_28,Kka2,kka2_1:2,P00552,0.562929,NO,28,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.883,-3.259,1.376,,0.353,S,B,0.22,2.02,2.655,,63.64,PPH,-1.74467,0.295029,0.00743084,0.562929 beta-lactamase_T27G,beta-lactamase_27,TEM-1,beta-lactamase,P62593,0.562934,NO,27,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.905,-3.36,1.455,5.39752,0.007,H,A,0.69,-0.37,0.745,,93.01,APH,-1.97933,0.221079,0.00306559,0.562934 beta-lactamase_2500_P224H,beta-lactamase_2500_224,TEM-1,beta-lactamase_2500,P62593,0.563062,NO,224,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.893,-4.649,3.756,,0.383,,B,0.52,-0.3,2.666,,74.48,HOH,-1.26433,0.361275,0.00189564,0.563062 kka2_1:2_L57I,kka2_1:2_57,Kka2,kka2_1:2,P00552,0.563122,NO,57,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.898,-2.89,0.992,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.295029,0.00723769,0.563122 beta-lactamase_2500_R220H,beta-lactamase_2500_220,TEM-1,beta-lactamase_2500,P62593,0.563149,NO,220,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-0.942,-4.298,3.356,,0.295,I,A,1.2,-0.76,2.175,,74.48,HBP,-1.33633,0.361275,0.00232421,0.563149 kka2_1:8_R226A,kka2_1:8_226,Kka2,kka2_1:8,P00552,0.563199,NO,226,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.392,-3.272,1.88,,0.222,H,A,0.16,-0.71,3.818,,56.06,PBA,-1.84767,0.100394,0.0108032,0.563199 kka2_1:8_R226A,kka2_1:8_226,Kka2,kka2_1:8,P00552,0.563199,NO,226,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.392,-3.272,1.88,,0.222,H,A,0.16,-0.71,3.818,,56.06,PBA,-1.84767,0.100394,0.0108032,0.563199 kka2_1:8_R226V,kka2_1:8_226,Kka2,kka2_1:8,P00552,0.563199,NO,226,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.392,-3.893,2.501,,0.222,H,A,0.16,-0.71,3.818,,56.06,PBA,-1.84767,0.100394,0.0108032,0.563199 kka2_1:8_R226V,kka2_1:8_226,Kka2,kka2_1:8,P00552,0.563199,NO,226,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.392,-3.893,2.501,,0.222,H,A,0.16,-0.71,3.818,,56.06,PBA,-1.84767,0.100394,0.0108032,0.563199 beta-lactamase_0_M115L,beta-lactamase_0_115,TEM-1,beta-lactamase_0,P62593,0.563275,NO,115,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.389,-1.859,0.47,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.0500837,0.0034337,0.563275 kka2_1:2_D154Y,kka2_1:2_154,Kka2,kka2_1:2,P00552,0.563335,NO,154,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.876,-4.417,3.541,,0.457,,b,0.29,1.48,3.631,,52.65,HAP,-1.52467,0.295029,0.00292633,0.563335 beta-lactamase_M66S,beta-lactamase_66,TEM-1,beta-lactamase,P62593,0.563363,NO,66,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.362,-3.571,2.209,5.29561,0.013,,A,1.3,-0.7,1.319,,73.08,OHH,-1.49567,0.221079,0.00412876,0.563363 kka2_1:2_D154I,kka2_1:2_154,Kka2,kka2_1:2,P00552,0.563495,NO,154,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.876,-4.094,3.218,,0.457,,b,0.29,1.48,3.631,,52.65,HAP,-1.52467,0.295029,0.00292633,0.563495 beta-lactamase_625_L191Q,beta-lactamase_625_191,TEM-1,beta-lactamase_625,P62593,0.563588,NO,191,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.087,-4.183,3.096,,,H,A,0.55,0.09,1.908,,63.29,BHH,-1.445,0.213352,0.00263549,0.563588 beta-lactamase_I283E,beta-lactamase_283,TEM-1,beta-lactamase,P62593,0.563706,NO,283,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.638,-3.806,2.168,5.4178,0.165,H,A,1.23,0.04,1.576,,69.23,HHB,-1.735,0.221079,0.0429138,0.563706 kka2_1:4_P12E,kka2_1:4_12,Kka2,kka2_1:4,P00552,0.563724,NO,12,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.853,-3.478,2.625,,,,B,0.52,1.25,0.843,,48.11,POH,-1.80767,0.168804,0.00500011,0.563724 kka2_1:1_A25T,kka2_1:1_25,Kka2,kka2_1:1,P00552,0.563778,NO,25,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.496,-2.626,0.13,,0.427,E,B,0.46,-0.47,6.872,6.872,65.53,HHP,-2.15167,0.520039,0.00595636,0.563778 beta-lactamase_I259T,beta-lactamase_259,TEM-1,beta-lactamase,P62593,0.563819,NO,259,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.522,-3.451,1.929,5.28457,,E,B,1,-0.8,1.24,,64.34,HHH,-1.53267,0.221079,0.0070773,0.563819 beta-lactamase_D231F,beta-lactamase_231,TEM-1,beta-lactamase,P62593,0.563822,NO,231,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.816,-4.318,3.502,5.06651,,E,B,1.22,-1.06,0.319,,65.38,HAB,-0.994,0.221079,0.00107395,0.563822 beta-lactamase_L135Y,beta-lactamase_135,TEM-1,beta-lactamase,P62593,0.563824,NO,135,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.002,-3.991,2.989,5.28497,0.117,H,A,1.07,-0.58,0.697,,43.71,PHH,-1.03767,0.221079,0.00244423,0.563824 beta-lactamase_R255Q,beta-lactamase_255,TEM-1,beta-lactamase,P62593,0.563827,NO,255,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.266,-4.118,1.852,5.55882,0.141,E,B,0.68,0.38,1.199,,63.99,PBH,-2.00433,0.221079,0.00499612,0.563827 kka2_1:8_V49K,kka2_1:8_49,Kka2,kka2_1:8,P00552,0.563865,NO,49,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.614,-3.819,2.205,,,E,B,1.48,-0.77,1.31,,64.39,HHB,-1.3,0.100394,0.00615685,0.563865 kka2_1:8_V49K,kka2_1:8_49,Kka2,kka2_1:8,P00552,0.563865,NO,49,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.614,-3.819,2.205,,,E,B,1.48,-0.77,1.31,,64.39,HHB,-1.3,0.100394,0.00615685,0.563865 Pab1_F146P,Pab1_146,Pab1,Pab1,P04147,0.563868,NO,146,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.149,-4.147,2.998,,0.006,H,A,,0.75,,,,PHP,-1.161,0.175299,0.000329265,0.563868 beta-lactamase_2500_L74I,beta-lactamase_2500_74,TEM-1,beta-lactamase_2500,P62593,0.563894,NO,74,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.296,-2.577,1.281,,,H,A,0.55,-0.91,0.746,,50,HHO,-1.34933,0.361275,0.00493255,0.563894 kka2_1:2_I254W,kka2_1:2_254,Kka2,kka2_1:2,P00552,0.563907,NO,254,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.933,-5.273,3.34,,0.135,H,A,1.52,-0.6,2.562,,71.59,BHH,-1.668,0.295029,0.0132375,0.563907 beta-lactamase_625_W288I,beta-lactamase_625_288,TEM-1,beta-lactamase_625,P62593,0.563948,NO,288,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,,,,,,,,,,,,,BHO,,0.213352,,0.563948 beta-lactamase_2500_R91M,beta-lactamase_2500_91,TEM-1,beta-lactamase_2500,P62593,0.564,NO,91,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.392,-4.593,3.201,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.361275,0.00380226,0.564 kka2_1:4_G99H,kka2_1:4_99,Kka2,kka2_1:4,P00552,0.564048,NO,99,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.596,-4.708,4.112,,0.368,S,g,0.29,-0.87,,,,OOP,-1.63067,0.168804,0.00186055,0.564048 kka2_1:2_P179C,kka2_1:2_179,Kka2,kka2_1:2,P00552,0.564105,NO,179,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.974,-5.011,4.037,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.295029,0.00298346,0.564105 beta-lactamase_2500_V82Q,beta-lactamase_2500_82,TEM-1,beta-lactamase_2500,P62593,0.56411,NO,82,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.325,-4.196,2.871,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.361275,0.00397046,0.56411 beta-lactamase_2500_V214R,beta-lactamase_2500_214,TEM-1,beta-lactamase_2500,P62593,0.564111,NO,214,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.299,-4.047,2.748,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.361275,0.00628442,0.564111 kka2_1:1_D220G,kka2_1:1_220,Kka2,kka2_1:1,P00552,0.564121,NO,220,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.787,-3.222,2.435,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.520039,0.00158066,0.564121 kka2_1:2_C77V,kka2_1:2_77,Kka2,kka2_1:2,P00552,0.564133,NO,77,C,V,CV,Special,Hydrophobic,5.07,5.60847,0.538465,192,121,117,-4,108.5,140,31.5,-1.477,-2.554,1.077,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.295029,0.00441216,0.564133 beta-lactamase_2500_T179I,beta-lactamase_2500_179,TEM-1,beta-lactamase_2500,P62593,0.564214,NO,179,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.085,-3.69,2.605,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.361275,0.00226045,0.564214 beta-lactamase_2500_L248C,beta-lactamase_2500_248,TEM-1,beta-lactamase_2500,P62593,0.564303,NO,248,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.361275,0.00428493,0.564303 beta-lactamase_P20V,beta-lactamase_20,TEM-1,beta-lactamase,P62593,0.564404,NO,20,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.74,-2.532,0.792,,,,,,,0.368,,67.83,HOH,-1.765,0.221079,0.00235322,0.564404 kka2_1:2_P249W,kka2_1:2_249,Kka2,kka2_1:2,P00552,0.564415,NO,249,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.867,-5.488,3.621,,0.406,.,B,0.52,-0.01,0.76,,92.05,HOA,-1.66867,0.295029,0.011045,0.564415 kka2_1:4_G99T,kka2_1:4_99,Kka2,kka2_1:4,P00552,0.564492,NO,99,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.596,-3.675,3.079,,0.368,S,g,0.29,-0.87,,,,OOP,-1.63067,0.168804,0.00186055,0.564492 Ubiquitin_K27W,Ubiquitin_27,Uba1,Ubiquitin,P0CG48,0.564516,NO,27,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.064,-5.29,4.226,4.77438,0.086,H,A,2.89,-0.74,2.662,,27.01,HBH,-1.42667,0.205827,0.000767556,0.564516 Ubiquitin_R42Y,Ubiquitin_42,Uba1,Ubiquitin,P0CG48,0.564516,NO,42,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.571,-4.025,2.454,5.07805,0.244,E,B,0.68,-0.54,1.976,,72.85,PBH,-1.38967,0.205827,0.000622265,0.564516 hsp90_Q582G,hsp90_582,hsp90,hsp90,P02829,0.564576,NO,582,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-3.278,-2.511,0,4.91603,0.453,S,B,,0.67,,,,OPH,-3.249,0.368192,0.000222939,0.564576 beta-lactamase_0_W288H,beta-lactamase_0_288,TEM-1,beta-lactamase_0,P62593,0.564599,NO,288,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,,,,,,,,,,,,,BHO,,0.0500837,,0.564599 beta-lactamase_2500_L55C,beta-lactamase_2500_55,TEM-1,beta-lactamase_2500,P62593,0.564878,NO,55,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.86,-4.909,3.049,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.361275,0.00403741,0.564878 kka2_1:2_L103V,kka2_1:2_103,Kka2,kka2_1:2,P00552,0.56495,NO,103,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-2.362,-2.108,-0.254,,0.394,T,A,0.55,-0.99,3.499,,63.64,HHP,-1.534,0.295029,0.00574792,0.56495 beta-lactamase_I229F,beta-lactamase_229,TEM-1,beta-lactamase,P62593,0.564992,NO,229,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.267,-3.792,2.525,5.0911,0.083,E,B,1,-0.76,1.114,,50,HHH,-1.58767,0.221079,0.00477249,0.564992 beta-lactamase_625_V117C,beta-lactamase_625_117,TEM-1,beta-lactamase_625,P62593,0.565065,NO,117,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.53,-4.787,3.257,,,H,A,0.44,-0.34,1.23,,65.03,PHB,-1.741,0.213352,0.00467906,0.565065 kka2_1:2_D220G,kka2_1:2_220,Kka2,kka2_1:2,P00552,0.565129,NO,220,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.787,-3.222,2.435,,,H,A,0.75,-1.14,0.745,,46.59,PAH,-1.152,0.295029,0.00158066,0.565129 kka2_1:2_G201L,kka2_1:2_201,Kka2,kka2_1:2,P00552,0.565234,NO,201,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.56,-3.824,2.264,,0.149,T,l,0.29,-0.57,16.092,16.092,52.65,POB,-1.92233,0.295029,0.00820117,0.565234 kka2_1:1_V198L,kka2_1:1_198,Kka2,kka2_1:1,P00552,0.565237,NO,198,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.719,-3.148,1.429,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.520039,0.00835002,0.565237 beta-lactamase_0_Y262D,beta-lactamase_0_262,TEM-1,beta-lactamase_0,P62593,0.565368,NO,262,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.0500837,0.00853516,0.565368 kka2_1:4_V36I,kka2_1:4_36,Kka2,kka2_1:4,P00552,0.565381,NO,36,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-0.898,-1.989,1.091,,0.292,E,B,0.44,0.21,0.278,,52.27,HHH,-1.484,0.168804,0.00245633,0.565381 kka2_1:1_D183G,kka2_1:1_183,Kka2,kka2_1:1,P00552,0.565394,NO,183,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.204,-3.336,2.132,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.520039,0.00426304,0.565394 kka2_1:2_R145A,kka2_1:2_145,Kka2,kka2_1:2,P00552,0.56549,NO,145,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.804,-2.368,0.564,,0.346,H,A,1.2,1.23,7.961,,63.64,HBP,-1.88033,0.295029,0.00846663,0.56549 kka2_1:2_I221M,kka2_1:2_221,Kka2,kka2_1:2,P00552,0.5655,NO,221,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.739,-4.064,2.325,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.295029,0.00945908,0.5655 beta-lactamase_2500_A183D,beta-lactamase_2500_183,TEM-1,beta-lactamase_2500,P62593,0.565587,NO,183,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.231,-2.686,1.455,,0.155,H,A,0.46,-0.91,12.189,,77.62,HHH,-1.53367,0.361275,0.00296631,0.565587 kka2_1:2_A79L,kka2_1:2_79,Kka2,kka2_1:2,P00552,0.565615,NO,79,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.368,-3.577,1.209,,0.563,.,B,0.46,-0.43,0.475,,71.59,HHH,-1.752,0.295029,0.00664821,0.565615 kka2_1:4_L60S,kka2_1:4_60,Kka2,kka2_1:4,P00552,0.565617,NO,60,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.997,-3.713,2.716,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.168804,0.00262176,0.565617 kka2_1:8_R217P,kka2_1:8_217,Kka2,kka2_1:8,P00552,0.565752,NO,217,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.158,-2.617,1.459,,0.252,T,A,0.16,-0.59,1.151,,52.27,ABH,-1.127,0.100394,0.0047191,0.565752 kka2_1:8_R217P,kka2_1:8_217,Kka2,kka2_1:8,P00552,0.565752,NO,217,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.158,-2.617,1.459,,0.252,T,A,0.16,-0.59,1.151,,52.27,ABH,-1.127,0.100394,0.0047191,0.565752 kka2_1:1_Q61L,kka2_1:1_61,Kka2,kka2_1:1,P00552,0.565754,NO,61,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.982,-2.984,0.002,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.520039,0.00612092,0.565754 beta-lactamase_R255C,beta-lactamase_255,TEM-1,beta-lactamase,P62593,0.565755,NO,255,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.266,-4.954,2.688,5.55882,0.141,E,B,0.68,0.38,1.199,,63.99,PBH,-2.00433,0.221079,0.00499612,0.565755 kka2_1:2_R140A,kka2_1:2_140,Kka2,kka2_1:2,P00552,0.565765,NO,140,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.351,-2.609,1.258,,0.12,H,A,1.2,0.2,0.352,,53.03,BBH,-1.885,0.295029,0.00430167,0.565765 beta-lactamase_2500_G236S,beta-lactamase_2500_236,TEM-1,beta-lactamase_2500,P62593,0.565796,NO,236,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.784,-2.475,1.691,,0.241,,b,0.29,-0.59,2.14,,64.69,HOO,-1.025,0.361275,0.00162372,0.565796 beta-lactamase_2500_A123V,beta-lactamase_2500_123,TEM-1,beta-lactamase_2500,P62593,0.565836,NO,123,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.834,-2.392,1.558,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.361275,0.0010157,0.565836 beta-lactamase_2500_R81E,beta-lactamase_2500_81,TEM-1,beta-lactamase_2500,P62593,0.565912,NO,81,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.466,-2.677,1.211,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.361275,0.00499763,0.565912 beta-lactamase_0_D48V,beta-lactamase_0_48,TEM-1,beta-lactamase_0,P62593,0.565913,NO,48,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.101,-3.719,2.618,,0.189,E,B,0.75,0.21,17.825,17.825,50.35,HAH,-1.62467,0.0500837,0.0027273,0.565913 kka2_1:1_D156G,kka2_1:1_156,Kka2,kka2_1:1,P00552,0.565953,NO,156,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.696,-3.383,1.687,,0.884,T,A,0.75,1.87,1.044,,65.53,PAA,-1.765,0.520039,0.00926998,0.565953 beta-lactamase_R271Y,beta-lactamase_271,TEM-1,beta-lactamase,P62593,0.565955,NO,271,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.249,-4.186,2.937,5.24516,0.085,H,A,1.67,-0.05,0.474,,63.99,ABP,-1.36633,0.221079,0.00752082,0.565955 beta-lactamase_Y44H,beta-lactamase_44,TEM-1,beta-lactamase,P62593,0.565961,NO,44,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-2.547,-4.769,2.222,5.6273,,E,B,2.55,-0.45,2.683,,73.78,OHH,-1.86267,0.221079,0.00426364,0.565961 beta-lactamase_625_M115T,beta-lactamase_625_115,TEM-1,beta-lactamase_625,P62593,0.566038,NO,115,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.389,-3.522,2.133,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.213352,0.0034337,0.566038 kka2_1:2_F203L,kka2_1:2_203,Kka2,kka2_1:2,P00552,0.566167,NO,203,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-0.911,-2.161,1.25,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.295029,0.00318738,0.566167 kka2_1:1_D157Y,kka2_1:1_157,Kka2,kka2_1:1,P00552,0.566175,NO,157,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.993,-4.444,3.451,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.520039,0.0042313,0.566175 beta-lactamase_Y95A,beta-lactamase_95,TEM-1,beta-lactamase,P62593,0.566354,NO,95,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-1.715,-3.364,1.649,5.67068,0.122,,b,0.96,-0.37,2.341,,77.62,BHP,-2.16167,0.221079,0.00479449,0.566354 beta-lactamase_C121V,beta-lactamase_121,TEM-1,beta-lactamase,P62593,0.566429,NO,121,C,V,CV,Special,Hydrophobic,5.07,5.60847,0.538465,192,121,117,-4,108.5,140,31.5,-0.953,-3.371,2.418,5.12205,,H,A,2.8,-0.81,7.644,,63.29,HOP,-1.46767,0.221079,0.000744322,0.566429 kka2_1:4_L158P,kka2_1:4_158,Kka2,kka2_1:4,P00552,0.566469,NO,158,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.947,-2.892,0.945,,0.095,,B,1.59,0.77,7.588,,63.64,AHA,-1.25333,0.168804,0.00529068,0.566469 beta-lactamase_625_I280F,beta-lactamase_625_280,TEM-1,beta-lactamase_625,P62593,0.566475,NO,280,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.213352,0.0530888,0.566475 kka2_1:1_N200S,kka2_1:1_200,Kka2,kka2_1:1,P00552,0.566503,NO,200,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-2.446,-2.785,0.339,,0.756,T,L,0.61,-0.08,17.299,17.299,64.39,APO,-2.08,0.520039,0.00838549,0.566503 kka2_1:2_E182V,kka2_1:2_182,Kka2,kka2_1:2,P00552,0.566543,NO,182,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.516,-3.667,2.151,,0.326,,B,1.52,0.75,14.547,14.547,65.53,OAA,-1.806,0.295029,0.00641548,0.566543 WW_domain_F189A,WW_domain_189,Yap65,WW_domain,P46937,0.566545,NO,189,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.632,-3.092,1.46,5.47284,,,,,,6.165,,56.94,HHH,-1.454,0.153962,0.00308453,0.566545 beta-lactamase_L79A,beta-lactamase_79,TEM-1,beta-lactamase,P62593,0.566562,NO,79,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.842,-3.103,2.261,4.98681,0.007,H,A,1.07,-0.16,0.823,,50.35,HHP,-1.44333,0.221079,0.000947397,0.566562 kka2_1:1_D23G,kka2_1:1_23,Kka2,kka2_1:1,P00552,0.566632,NO,23,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.459,-2.651,0.192,,0.695,E,B,0.75,-0.65,2.655,,65.53,HAH,-1.94033,0.520039,0.007195,0.566632 beta-lactamase_2500_L73G,beta-lactamase_2500_73,TEM-1,beta-lactamase_2500,P62593,0.566738,NO,73,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.507,-3.739,2.232,,,H,A,0.55,-0.64,2.178,,67.83,HHH,-1.487,0.361275,0.00488983,0.566738 kka2_1:4_R140H,kka2_1:4_140,Kka2,kka2_1:4,P00552,0.566738,NO,140,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.351,-4.514,3.163,,0.12,H,A,1.2,0.2,2.561,,53.03,BBH,-1.885,0.168804,0.00430167,0.566738 beta-lactamase_156_D155C,beta-lactamase_156_155,TEM-1,beta-lactamase_156,P62593,0.566748,NO,155,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.889,-5.157,4.268,,0.049,,B,0.75,-0.9,0.315,,64.69,OAB,-1.62267,0.111618,0.00135315,0.566748 beta-lactamase_625_G114C,beta-lactamase_625_114,TEM-1,beta-lactamase_625,P62593,0.566833,NO,114,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.094,-5.014,3.92,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.213352,0.00224919,0.566833 kka2_1:1_T28M,kka2_1:1_28,Kka2,kka2_1:1,P00552,0.566844,NO,28,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.883,-3.567,1.684,,0.353,S,B,0.22,2.02,1.12,,63.64,PPH,-1.74467,0.520039,0.00743084,0.566844 beta-lactamase_V117N,beta-lactamase_117,TEM-1,beta-lactamase,P62593,0.566868,NO,117,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.53,-4.224,2.694,5.33594,,H,A,1.19,-0.34,1.182,,65.03,PHB,-1.741,0.221079,0.00467906,0.566868 beta-lactamase_2500_V214H,beta-lactamase_2500_214,TEM-1,beta-lactamase_2500,P62593,0.567104,NO,214,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.299,-4.922,3.623,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.361275,0.00628442,0.567104 kka2_1:1_K138T,kka2_1:1_138,Kka2,kka2_1:1,P00552,0.567154,NO,138,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-2.5,-2.841,0.341,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.520039,0.00628542,0.567154 beta-lactamase_156_T69G,beta-lactamase_156_69,TEM-1,beta-lactamase_156,P62593,0.567165,NO,69,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-0.973,-3.289,2.316,,,G,A,0.22,-1.24,4.194,,93.01,PPH,-1.01833,0.111618,0.00127498,0.567165 kka2_1:2_A64D,kka2_1:2_64,Kka2,kka2_1:2,P00552,0.567299,NO,64,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.496,-3.892,2.396,,0.039,H,A,0.46,-0.57,14.509,14.509,56.06,AHH,-1.334,0.295029,0.00705578,0.567299 beta-lactamase_0_A225E,beta-lactamase_0_225,TEM-1,beta-lactamase_0,P62593,0.567318,NO,225,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.845,-2.246,0.401,,1,T,B,0.46,-0.38,11.722,11.722,74.48,OHO,-1.39967,0.0500837,0.00465057,0.567318 beta-lactamase_0_D174N,beta-lactamase_0_174,TEM-1,beta-lactamase_0,P62593,0.567363,NO,174,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.738,-3.223,2.485,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.0500837,0.00125633,0.567363 WW_domain_L173Q,WW_domain_173,Yap65,WW_domain,P46937,0.567373,NO,173,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.117,-3.901,2.784,,,,,,,,,,OHO,-1.06233,0.153962,0.000851849,0.567373 kka2_1:4_D52Y,kka2_1:4_52,Kka2,kka2_1:4,P00552,0.567384,NO,52,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.271,-4.235,1.964,,0.22,E,B,0.75,0.8,0.349,,71.59,PAH,-2.38367,0.168804,0.00175694,0.567384 beta-lactamase_2500_S51L,beta-lactamase_2500_51,TEM-1,beta-lactamase_2500,P62593,0.567426,NO,51,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.526,-3.495,1.969,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.361275,0.00504821,0.567426 beta-lactamase_156_L79G,beta-lactamase_156_79,TEM-1,beta-lactamase_156,P62593,0.567434,NO,79,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.842,-3.806,2.964,,0.007,H,A,0.55,-0.16,1.831,,50.35,HHP,-1.44333,0.111618,0.000947397,0.567434 kka2_1:1_S40K,kka2_1:1_40,Kka2,kka2_1:1,P00552,0.567507,NO,40,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.645,-2.814,0.169,,0.32,E,B,0.27,-0.9,25.997,25.997,71.59,HPH,-1.91567,0.520039,0.00693477,0.567507 beta-lactamase_0_Y262V,beta-lactamase_0_262,TEM-1,beta-lactamase_0,P62593,0.567527,NO,262,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.0500837,0.00853516,0.567527 kka2_1:2_E169M,kka2_1:2_169,Kka2,kka2_1:2,P00552,0.567547,NO,169,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.996,-3.601,1.605,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.295029,0.00730086,0.567547 kka2_1:4_A117S,kka2_1:4_117,Kka2,kka2_1:4,P00552,0.56758,NO,117,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.828,-3.072,2.244,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.168804,0.00282984,0.56758 beta-lactamase_625_L55D,beta-lactamase_625_55,TEM-1,beta-lactamase_625,P62593,0.567633,NO,55,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.86,-4.094,2.234,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.213352,0.00403741,0.567633 beta-lactamase_P224V,beta-lactamase_224,TEM-1,beta-lactamase,P62593,0.567633,NO,224,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.893,-3.599,2.706,5.179,0.383,,B,0.99,-0.3,0.383,,74.48,HOH,-1.26433,0.221079,0.00189564,0.567633 kka2_1:8_I115Q,kka2_1:8_115,Kka2,kka2_1:8,P00552,0.567658,NO,115,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.606,-4.312,2.706,,0.105,H,A,1.52,-1.18,4.064,,65.53,PHH,-2.205,0.100394,0.00836567,0.567658 kka2_1:8_I115Q,kka2_1:8_115,Kka2,kka2_1:8,P00552,0.567658,NO,115,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.606,-4.312,2.706,,0.105,H,A,1.52,-1.18,4.064,,65.53,PHH,-2.205,0.100394,0.00836567,0.567658 kka2_1:1_F263S,kka2_1:1_263,Kka2,kka2_1:1,P00552,0.567668,NO,263,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-0.911,-3.673,2.762,,0.006,G,A,0.58,-0.12,2.284,,45.83,AHH,-0.92,0.520039,0.0172454,0.567668 kka2_1:8_L193G,kka2_1:8_193,Kka2,kka2_1:8,P00552,0.56772,NO,193,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.983,-3.8,2.817,,,G,A,1.59,-1.03,2.234,,65.53,OHO,-0.965333,0.100394,0.00480179,0.56772 kka2_1:8_L193G,kka2_1:8_193,Kka2,kka2_1:8,P00552,0.56772,NO,193,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.983,-3.8,2.817,,,G,A,1.59,-1.03,2.234,,65.53,OHO,-0.965333,0.100394,0.00480179,0.56772 beta-lactamase_L219S,beta-lactamase_219,TEM-1,beta-lactamase,P62593,0.567723,NO,219,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.313,-3.686,2.373,5.74153,,I,A,0.84,-0.51,2.321,,74.48,HHB,-1.21533,0.221079,0.00664345,0.567723 kka2_1:1_T51A,kka2_1:1_51,Kka2,kka2_1:1,P00552,0.567763,NO,51,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.199,-2.346,0.147,,0.05,E,B,0.22,-0.05,3.056,,63.64,BPA,-1.76767,0.520039,0.00628861,0.567763 kka2_1:8_A237K,kka2_1:8_237,Kka2,kka2_1:8,P00552,0.567781,NO,237,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.12,-3.814,1.694,,0.068,H,A,0.46,-0.71,0.449,,92.05,HHA,-2.10433,0.100394,0.012257,0.567781 kka2_1:8_A237K,kka2_1:8_237,Kka2,kka2_1:8,P00552,0.567781,NO,237,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.12,-3.814,1.694,,0.068,H,A,0.46,-0.71,0.449,,92.05,HHA,-2.10433,0.100394,0.012257,0.567781 beta-lactamase_2500_R162G,beta-lactamase_2500_162,TEM-1,beta-lactamase_2500,P62593,0.567818,NO,162,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.016,-3.445,2.429,,0.124,S,B,1.2,-0.37,6.199,,64.69,ABH,-1.25,0.361275,0.000561334,0.567818 beta-lactamase_156_G240R,beta-lactamase_156_240,TEM-1,beta-lactamase_156,P62593,0.567908,NO,240,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.111618,0.00591201,0.567908 PSD95pdz3_L353K,PSD95pdz3_353,PSD95pdz3,PSD95pdz3,P31016,0.567922,NO,353,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.347,-3.364,2.017,5.81136,,,,,17.3525,,,,AHB,-1.50533,0.0758425,0.000664742,0.567922 beta-lactamase_0_E195M,beta-lactamase_0_195,TEM-1,beta-lactamase_0,P62593,0.567931,NO,195,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.186,-4.856,2.67,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.0500837,0.00496565,0.567931 beta-lactamase_625_Y103D,beta-lactamase_625_103,TEM-1,beta-lactamase_625,P62593,0.567978,NO,103,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-1.33,-3.794,2.464,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.213352,0.00443048,0.567978 beta-lactamase_625_F64V,beta-lactamase_625_64,TEM-1,beta-lactamase_625,P62593,0.567987,NO,64,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-0.841,-3.304,2.463,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.213352,0.000947691,0.567987 kka2_1:2_A222D,kka2_1:2_222,Kka2,kka2_1:2,P00552,0.568023,NO,222,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.725,-3.722,2.997,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.295029,0.00207657,0.568023 kka2_1:2_R89L,kka2_1:2_89,Kka2,kka2_1:2,P00552,0.568117,NO,89,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.548,-3.591,2.043,,0.209,E,B,1.2,1.41,14.396,14.396,64.39,OBA,-1.89867,0.295029,0.00524373,0.568117 kka2_1:4_R140F,kka2_1:4_140,Kka2,kka2_1:4,P00552,0.5682,NO,140,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.351,-4.407,3.056,,0.12,H,A,1.2,0.2,2.561,,53.03,BBH,-1.885,0.168804,0.00430167,0.5682 beta-lactamase_R220V,beta-lactamase_220,TEM-1,beta-lactamase,P62593,0.568218,NO,220,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-0.942,-3.675,2.733,5.65995,0.295,I,A,0.68,-0.76,2.164,,74.48,HBP,-1.33633,0.221079,0.00232421,0.568218 beta-lactamase_T131N,beta-lactamase_131,TEM-1,beta-lactamase,P62593,0.568255,NO,131,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.328,-3.603,2.275,5.0548,,H,A,0.53,-0.69,3.306,,67.48,PPH,-1.00867,0.221079,0.00345886,0.568255 PSD95pdz3_I359G,PSD95pdz3_359,PSD95pdz3,PSD95pdz3,P31016,0.568283,NO,359,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.63,-3.49,1.86,5.35151,,,,,14.8012,,,,PHH,-1.58667,0.0758425,0.000580694,0.568283 beta-lactamase_625_D155E,beta-lactamase_625_155,TEM-1,beta-lactamase_625,P62593,0.568292,NO,155,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.889,-2.299,1.41,,0.049,,B,0.75,-0.9,4.922,,64.69,OAB,-1.62267,0.213352,0.00135315,0.568292 beta-lactamase_L219Q,beta-lactamase_219,TEM-1,beta-lactamase,P62593,0.5683,NO,219,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.313,-4.292,2.979,5.74153,,I,A,0.84,-0.51,2.321,,74.48,HHB,-1.21533,0.221079,0.00664345,0.5683 beta-lactamase_Y260C,beta-lactamase_260,TEM-1,beta-lactamase,P62593,0.568342,NO,260,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-1.101,-4.903,3.802,5.50878,,E,B,0.73,-1.04,0.865,,60.49,HHP,-1.83433,0.221079,0.00471757,0.568342 beta-lactamase_2500_I261F,beta-lactamase_2500_261,TEM-1,beta-lactamase_2500,P62593,0.568399,NO,261,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.361275,0.0123091,0.568399 beta-lactamase_2500_V260G,beta-lactamase_2500_260,TEM-1,beta-lactamase_2500,P62593,0.568441,NO,260,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.361275,0.00471757,0.568441 beta-lactamase_2500_D174C,beta-lactamase_2500_174,TEM-1,beta-lactamase_2500,P62593,0.568527,NO,174,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.738,-5.087,4.349,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.361275,0.00125633,0.568527 beta-lactamase_2500_R92C,beta-lactamase_2500_92,TEM-1,beta-lactamase_2500,P62593,0.568574,NO,92,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.718,-5.119,3.401,,0.479,E,B,1.2,1.36,3.069,,65.38,BBH,-1.50367,0.361275,0.00429626,0.568574 beta-lactamase_625_D83V,beta-lactamase_625_83,TEM-1,beta-lactamase_625,P62593,0.56862,NO,83,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.066,-3.762,2.696,,0.354,H,A,0.75,0.22,0.239,,48.95,HAH,-1.34733,0.213352,0.00205968,0.56862 kka2_1:1_K175V,kka2_1:1_175,Kka2,kka2_1:1,P00552,0.5687,NO,175,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-2.897,-2.802,-0.095,,0.579,H,A,1.3,0.51,9.33,9.33,71.59,HBH,-1.82333,0.520039,0.00693093,0.5687 kka2_1:2_G164E,kka2_1:2_164,Kka2,kka2_1:2,P00552,0.568731,NO,164,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.869,-3.557,2.688,,0.862,T,l,0.75,1.45,1.539,,64.39,POH,-1.828,0.295029,0.00442091,0.568731 kka2_1:4_C131F,kka2_1:4_131,Kka2,kka2_1:4,P00552,0.568768,NO,131,C,F,CF,Special,Hydrophobic,5.07,3.32051,-1.74949,205,121,165,44,108.5,189.9,81.4,-0.831,-4.095,3.264,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.168804,0.00170814,0.568768 beta-lactamase_156_E279P,beta-lactamase_156_279,TEM-1,beta-lactamase_156,P62593,0.568856,NO,279,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.111618,0.0192826,0.568856 kka2_1:2_L126R,kka2_1:2_126,Kka2,kka2_1:2,P00552,0.568859,NO,126,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.246,-4.098,2.852,,0.285,S,B,0.55,0.12,1.392,,51.89,PHA,-1.744,0.295029,0.0066485,0.568859 beta-lactamase_L137W,beta-lactamase_137,TEM-1,beta-lactamase,P62593,0.568884,NO,137,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.03,-5.164,4.134,5.20117,,H,A,1.07,-0.38,0.674,,42.31,HHP,-1.58933,0.221079,0.00278599,0.568884 beta-lactamase_2500_R81W,beta-lactamase_2500_81,TEM-1,beta-lactamase_2500,P62593,0.568953,NO,81,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.466,-5.415,3.949,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.361275,0.00499763,0.568953 beta-lactamase_2500_T131L,beta-lactamase_2500_131,TEM-1,beta-lactamase_2500,P62593,0.568959,NO,131,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.328,-3.319,1.991,,,H,A,0.22,-0.69,3.048,,67.48,PPH,-1.00867,0.361275,0.00345886,0.568959 beta-lactamase_2500_V72S,beta-lactamase_2500_72,TEM-1,beta-lactamase_2500,P62593,0.569039,NO,72,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.658,-3.477,1.819,,,H,A,0.44,-1.03,2.079,,65.73,BHH,-1.32167,0.361275,0.00501194,0.569039 beta-lactamase_2500_S96P,beta-lactamase_2500_96,TEM-1,beta-lactamase_2500,P62593,0.569064,NO,96,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.27,-2.878,0.608,,0.368,,b,0.27,0.39,32.348,32.348,73.78,HPP,-2.019,0.361275,0.00551835,0.569064 kka2_1:1_A150V,kka2_1:1_150,Kka2,kka2_1:1,P00552,0.56908,NO,150,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.949,-3.306,2.357,,0.544,T,A,0.46,1.34,2.333,,63.26,AHO,-1.272,0.520039,0.0045009,0.56908 PSD95pdz3_Q391P,PSD95pdz3_391,PSD95pdz3,PSD95pdz3,P31016,0.569093,NO,391,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-1.699,-3.336,1.637,5.50275,,,,,12.6589,,,,HPH,-1.481,0.0758425,0.000990786,0.569093 kka2_1:2_N200V,kka2_1:2_200,Kka2,kka2_1:2,P00552,0.569133,NO,200,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-2.446,-3.862,1.416,,0.756,T,L,0.61,-0.08,2.836,,64.39,APO,-2.08,0.295029,0.00838549,0.569133 beta-lactamase_2500_P105T,beta-lactamase_2500_105,TEM-1,beta-lactamase_2500,P62593,0.569303,NO,105,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.813,-3.385,2.572,,0.226,T,A,0.52,0.8,3.1,,63.29,POH,-1.01533,0.361275,0.0011981,0.569303 kka2_1:1_V49M,kka2_1:1_49,Kka2,kka2_1:1,P00552,0.569316,NO,49,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.614,-4.13,2.516,,,E,B,0.44,-0.77,3.665,3.665,64.39,HHB,-1.3,0.520039,0.00615685,0.569316 kka2_1:1_A108E,kka2_1:1_108,Kka2,kka2_1:1,P00552,0.569394,NO,108,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.061,-2.517,0.456,,0.243,.,B,0.46,-1.34,3.156,,71.59,HHO,-1.57033,0.520039,0.00751209,0.569394 beta-lactamase_625_P224W,beta-lactamase_625_224,TEM-1,beta-lactamase_625,P62593,0.569411,NO,224,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.893,-5.546,4.653,,0.383,,B,0.52,-0.3,1.35,,74.48,HOH,-1.26433,0.213352,0.00189564,0.569411 beta-lactamase_0_L49Q,beta-lactamase_0_49,TEM-1,beta-lactamase_0,P62593,0.569425,NO,49,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.897,-2.823,0.926,,0.131,T,A,0.55,0.04,13.838,13.838,64.69,AHP,-1.99233,0.0500837,0.00401477,0.569425 beta-lactamase_2500_T27A,beta-lactamase_2500_27,TEM-1,beta-lactamase_2500,P62593,0.569508,NO,27,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.905,-2.5,0.595,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.361275,0.00306559,0.569508 kka2_1:2_M148A,kka2_1:2_148,Kka2,kka2_1:2,P00552,0.569552,NO,148,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.847,-2.283,0.436,,0.268,H,A,1.59,0.71,1.439,,64.39,BHA,-1.65467,0.295029,0.00982664,0.569552 kka2_1:8_M197T,kka2_1:8_197,Kka2,kka2_1:8,P00552,0.569736,NO,197,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.707,-2.639,0.932,,0.121,E,B,1.59,-1.19,4.408,,65.53,HHH,-1.847,0.100394,0.00921295,0.569736 kka2_1:8_M197T,kka2_1:8_197,Kka2,kka2_1:8,P00552,0.569736,NO,197,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.707,-2.639,0.932,,0.121,E,B,1.59,-1.19,4.408,,65.53,HHH,-1.847,0.100394,0.00921295,0.569736 gb1_F256K,gb1_256,gb1,gb1,P06654,0.56978,NO,256,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.241,-3.684,2.443,,,,,,,,,,HHB,-2.04767,0.177985,0.00435993,0.56978 gb1_Y229P,gb1_229,gb1,gb1,P06654,0.56978,NO,229,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-1.282,-3.84,2.558,,,,,,,,,,PHB,-1.4915,0.177985,0.00366605,0.56978 PSD95pdz3_G330A,PSD95pdz3_330,PSD95pdz3,PSD95pdz3,P31016,0.569798,NO,330,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.008,-2.534,1.526,4.68351,,,,,31.405,,,,OOA,-1.14,0.0758425,0.000962386,0.569798 kka2_1:4_L193V,kka2_1:4_193,Kka2,kka2_1:4,P00552,0.569861,NO,193,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.983,-3.044,2.061,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.168804,0.00480179,0.569861 beta-lactamase_0_T107Y,beta-lactamase_0_107,TEM-1,beta-lactamase_0,P62593,0.569865,NO,107,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.117,-4.214,3.097,,,G,A,0.22,-0.06,3.73,,67.83,HPA,-1.265,0.0500837,0.00239347,0.569865 kka2_1:1_A117R,kka2_1:1_117,Kka2,kka2_1:1,P00552,0.569887,NO,117,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.828,-3.824,2.996,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.520039,0.00282984,0.569887 kka2_1:2_E111S,kka2_1:2_111,Kka2,kka2_1:2,P00552,0.56991,NO,111,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.28,-2.706,0.426,,0.155,H,A,1.52,-1.14,2.792,,65.53,HAB,-2.27833,0.295029,0.00746789,0.56991 kka2_1:1_D180R,kka2_1:1_180,Kka2,kka2_1:1,P00552,0.569986,NO,180,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.416,-2.973,0.557,,1.03,S,a,0.75,1.5,1.534,,71.59,OAO,-2.02933,0.520039,0.00756412,0.569986 kka2_1:1_A9Y,kka2_1:1_9,Kka2,kka2_1:1,P00552,0.570017,NO,9,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.079,-4.09,2.011,,,,,,,0.383,,71.59,BHO,-2.253,0.520039,0.00273264,0.570017 kka2_1:4_R143P,kka2_1:4_143,Kka2,kka2_1:4,P00552,0.570163,NO,143,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.525,-4.091,1.566,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.168804,0.00662247,0.570163 beta-lactamase_2500_R242C,beta-lactamase_2500_242,TEM-1,beta-lactamase_2500,P62593,0.57019,NO,242,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.361275,0.00452879,0.57019 beta-lactamase_2500_L89P,beta-lactamase_2500_89,TEM-1,beta-lactamase_2500,P62593,0.570213,NO,89,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.096,-2.221,1.125,,0.168,T,A,0.55,0.63,2.066,,64.34,PHO,-1.75767,0.361275,0.00207068,0.570213 beta-lactamase_D36Q,beta-lactamase_36,TEM-1,beta-lactamase,P62593,0.570221,NO,36,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.732,-2.234,-0.498,5.39764,0.555,H,A,0.11,1.17,13.689,13.689,77.62,AAP,-1.91167,0.221079,0.00476483,0.570221 kka2_1:4_Q219S,kka2_1:4_219,Kka2,kka2_1:4,P00552,0.570314,NO,219,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-0.93,-3.233,2.303,,0.088,H,A,0.64,-0.85,1.537,,50,HPA,-1.05167,0.168804,0.00237913,0.570314 beta-lactamase_625_D231L,beta-lactamase_625_231,TEM-1,beta-lactamase_625,P62593,0.570344,NO,231,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.816,-3.806,2.99,,,E,B,0.75,-1.06,1.025,,65.38,HAB,-0.994,0.213352,0.00107395,0.570344 kka2_1:2_L152P,kka2_1:2_152,Kka2,kka2_1:2,P00552,0.570351,NO,152,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.521,-4.119,2.598,,0.547,.,A,0.55,1.36,4.526,,63.64,OHH,-1.162,0.295029,0.00674868,0.570351 kka2_1:2_C209F,kka2_1:2_209,Kka2,kka2_1:2,P00552,0.570394,NO,209,C,F,CF,Special,Hydrophobic,5.07,3.32051,-1.74949,205,121,165,44,108.5,189.9,81.4,-0.906,-4.063,3.157,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.295029,0.00260862,0.570394 beta-lactamase_39_K232C,beta-lactamase_39_232,TEM-1,beta-lactamase_39,P62593,0.570446,NO,232,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.012,-5.13,4.118,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.0495842,0.00313441,0.570446 beta-lactamase_0_C121R,beta-lactamase_0_121,TEM-1,beta-lactamase_0,P62593,0.570454,NO,121,C,R,CR,Special,PositiveCharge,5.07,6.34148,1.27148,180,121,174,53,108.5,173.4,64.9,-0.953,-2.762,1.809,,,H,A,0.46,-0.81,3.302,,63.29,HOP,-1.46767,0.0500837,0.000744322,0.570454 beta-lactamase_156_F64Q,beta-lactamase_156_64,TEM-1,beta-lactamase_156,P62593,0.570483,NO,64,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-0.841,-4.349,3.508,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.111618,0.000947691,0.570483 beta-lactamase_2500_D212A,beta-lactamase_2500_212,TEM-1,beta-lactamase_2500,P62593,0.570588,NO,212,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.624,-2.64,1.016,,0.037,,b,0.75,-0.58,12.482,,74.48,HAB,-1.77667,0.361275,0.00644302,0.570588 Pab1_F170A,Pab1_170,Pab1,Pab1,P04147,0.570644,NO,170,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.269,-3.173,1.904,,0.331,E,B,0.87,-1.31,2.061,,79.72,OHH,-1.06367,0.175299,0.000540225,0.570644 kka2_1:2_K138L,kka2_1:2_138,Kka2,kka2_1:2,P00552,0.570682,NO,138,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-2.5,-3.647,1.147,,0.594,H,A,2.34,0.98,21.038,21.038,71.59,HBB,-2.48833,0.295029,0.00628542,0.570682 kka2_1:2_G74V,kka2_1:2_74,Kka2,kka2_1:2,P00552,0.570884,NO,74,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.18,-3.881,2.701,,0.621,T,l,0.75,0.2,1.446,,64.39,POH,-1.91667,0.295029,0.00587035,0.570884 kka2_1:4_A78E,kka2_1:4_78,Kka2,kka2_1:4,P00552,0.570936,NO,78,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.744,-3.513,1.769,,0.078,.,B,0.46,-0.53,0.594,,56.06,OHH,-1.863,0.168804,0.00457299,0.570936 beta-lactamase_L197P,beta-lactamase_197,TEM-1,beta-lactamase,P62593,0.571009,NO,197,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.853,-4.068,3.215,5.19172,0.007,S,B,1.3,0.33,1.756,,60.14,HHP,-1.833,0.221079,0.00144602,0.571009 kka2_1:2_P194L,kka2_1:2_194,Kka2,kka2_1:2,P00552,0.571011,NO,194,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.846,-3.652,2.806,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.295029,0.00314194,0.571011 beta-lactamase_I206D,beta-lactamase_206,TEM-1,beta-lactamase,P62593,0.571036,NO,206,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-2.429,-3.794,1.365,5.3727,0.173,H,A,1,-0.34,2.061,,77.62,HHA,-1.805,0.221079,0.00528934,0.571036 beta-lactamase_P65T,beta-lactamase_65,TEM-1,beta-lactamase,P62593,0.571071,NO,65,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.894,-3.44,2.546,5.59094,0.098,E,B,0.23,-0.62,0.623,,40.56,HOH,-1.03233,0.221079,0.00152776,0.571071 kka2_1:8_F203S,kka2_1:8_203,Kka2,kka2_1:8,P00552,0.571074,NO,203,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-0.911,-3.673,2.762,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.100394,0.00318738,0.571074 kka2_1:8_F203S,kka2_1:8_203,Kka2,kka2_1:8,P00552,0.571074,NO,203,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-0.911,-3.673,2.762,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.100394,0.00318738,0.571074 kka2_1:1_R121G,kka2_1:1_121,Kka2,kka2_1:1,P00552,0.571097,NO,121,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.552,-3.527,1.975,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.520039,0.00523326,0.571097 beta-lactamase_625_R220H,beta-lactamase_625_220,TEM-1,beta-lactamase_625,P62593,0.571156,NO,220,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-0.942,-4.298,3.356,,0.295,I,A,1.2,-0.76,5.086,,74.48,HBP,-1.33633,0.213352,0.00232421,0.571156 kka2_1:8_A224D,kka2_1:8_224,Kka2,kka2_1:8,P00552,0.571256,NO,224,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.977,-3.763,2.786,,,H,A,0.46,-1.26,0.357,,63.64,HHP,-1.41033,0.100394,0.00352047,0.571256 kka2_1:8_A224D,kka2_1:8_224,Kka2,kka2_1:8,P00552,0.571256,NO,224,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.977,-3.763,2.786,,,H,A,0.46,-1.26,0.357,,63.64,HHP,-1.41033,0.100394,0.00352047,0.571256 beta-lactamase_2500_P105K,beta-lactamase_2500_105,TEM-1,beta-lactamase_2500,P62593,0.571475,NO,105,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.813,-3.454,2.641,,0.226,T,A,0.52,0.8,3.1,,63.29,POH,-1.01533,0.361275,0.0011981,0.571475 kka2_1:2_R122G,kka2_1:2_122,Kka2,kka2_1:2,P00552,0.571508,NO,122,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.175,-2.63,0.455,,0.487,H,A,1.2,0.26,16.436,16.436,71.59,BBH,-1.53833,0.295029,0.00736512,0.571508 beta-lactamase_2500_T263E,beta-lactamase_2500_263,TEM-1,beta-lactamase_2500,P62593,0.571518,NO,263,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.361275,0.0110582,0.571518 kka2_1:8_R202W,kka2_1:8_202,Kka2,kka2_1:8,P00552,0.571559,NO,202,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.761,-5.54,3.779,,0.607,E,B,1.2,0.48,1.409,,52.27,OBH,-1.41067,0.100394,0.00696498,0.571559 kka2_1:8_R202W,kka2_1:8_202,Kka2,kka2_1:8,P00552,0.571559,NO,202,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.761,-5.54,3.779,,0.607,E,B,1.2,0.48,1.409,,52.27,OBH,-1.41067,0.100394,0.00696498,0.571559 beta-lactamase_0_G253E,beta-lactamase_0_253,TEM-1,beta-lactamase_0,P62593,0.571619,NO,253,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.0500837,0.00786358,0.571619 beta-lactamase_156_I280W,beta-lactamase_156_280,TEM-1,beta-lactamase_156,P62593,0.571643,NO,280,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.111618,0.0530888,0.571643 kka2_1:8_L170Q,kka2_1:8_170,Kka2,kka2_1:8,P00552,0.57174,NO,170,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.28,-4.219,2.939,,0.029,H,A,1.59,0.11,1.453,,62.5,AHH,-1.534,0.100394,0.00730791,0.57174 kka2_1:8_L170Q,kka2_1:8_170,Kka2,kka2_1:8,P00552,0.57174,NO,170,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.28,-4.219,2.939,,0.029,H,A,1.59,0.11,1.453,,62.5,AHH,-1.534,0.100394,0.00730791,0.57174 kka2_1:2_L123P,kka2_1:2_123,Kka2,kka2_1:2,P00552,0.571895,NO,123,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.888,-4.155,3.267,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.295029,0.00325188,0.571895 beta-lactamase_625_I244A,beta-lactamase_625_244,TEM-1,beta-lactamase_625,P62593,0.572096,NO,244,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.555,-3.008,1.453,,,E,B,0.48,-0.84,2.061,,77.62,OHH,-1.385,0.213352,0.00605379,0.572096 kka2_1:4_A237L,kka2_1:4_237,Kka2,kka2_1:4,P00552,0.572134,NO,237,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.12,-2.076,-0.044,,0.068,H,A,0.46,-0.71,2.444,,92.05,HHA,-2.10433,0.168804,0.012257,0.572134 kka2_1:1_I2S,kka2_1:1_2,Kka2,kka2_1:1,P00552,0.572147,NO,2,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.787,-3.207,1.42,,,,,,,2.329,,71.59,HHA,-1.92433,0.520039,0.00246644,0.572147 kka2_1:8_Y218G,kka2_1:8_218,Kka2,kka2_1:8,P00552,0.572178,NO,218,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-1.438,-3.625,2.187,,0.122,H,A,1.25,-0.69,2.923,,56.06,BHP,-1.17533,0.100394,0.0126098,0.572178 kka2_1:8_Y218G,kka2_1:8_218,Kka2,kka2_1:8,P00552,0.572178,NO,218,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-1.438,-3.625,2.187,,0.122,H,A,1.25,-0.69,2.923,,56.06,BHP,-1.17533,0.100394,0.0126098,0.572178 kka2_1:1_D5M,kka2_1:1_5,Kka2,kka2_1:1,P00552,0.572306,NO,5,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.306,-4.66,3.354,,,,,,,0.895,,71.59,PAO,-1.784,0.520039,0.00222864,0.572306 kka2_1:2_C77S,kka2_1:2_77,Kka2,kka2_1:2,P00552,0.572337,NO,77,C,S,CS,Special,Polar,5.07,5.68,0.61,112,121,105,-16,108.5,89,-19.5,-1.477,-2.746,1.269,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.295029,0.00441216,0.572337 beta-lactamase_156_G240K,beta-lactamase_156_240,TEM-1,beta-lactamase_156,P62593,0.572338,NO,240,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.111618,0.00591201,0.572338 beta-lactamase_2500_V259T,beta-lactamase_2500_259,TEM-1,beta-lactamase_2500,P62593,0.572355,NO,259,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.361275,0.0070773,0.572355 beta-lactamase_156_V72H,beta-lactamase_156_72,TEM-1,beta-lactamase_156,P62593,0.572357,NO,72,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.658,-4.908,3.25,,,H,A,0.44,-1.03,1.92,,65.73,BHH,-1.32167,0.111618,0.00501194,0.572357 Pab1_I137N,Pab1_137,Pab1,Pab1,P04147,0.572368,NO,137,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.212,-3.94,2.728,,0.068,,B,0.77,0.35,,,,AHA,-1.314,0.175299,0.000342224,0.572368 kka2_1:1_T72A,kka2_1:1_72,Kka2,kka2_1:1,P00552,0.572372,NO,72,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.38,-2.118,-0.262,,0.784,H,A,0.22,0.29,10.43,10.43,65.53,HPP,-2.238,0.520039,0.00750756,0.572372 beta-lactamase_0_D83T,beta-lactamase_0_83,TEM-1,beta-lactamase_0,P62593,0.572538,NO,83,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.066,-3.464,2.398,,0.354,H,A,0.75,0.22,0.617,,48.95,HAH,-1.34733,0.0500837,0.00205968,0.572538 Ubiquitin_G10H,Ubiquitin_10,Uba1,Ubiquitin,P0CG48,0.572581,NO,10,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.396,-4.557,3.161,5.29806,0.115,S,l,,0.2,,,,POB,-1.38633,0.205827,0.000748953,0.572581 Ubiquitin_H68M,Ubiquitin_68,Uba1,Ubiquitin,P0CG48,0.572581,NO,68,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-1.869,-4.674,2.805,4.81902,0.194,E,B,0.72,-1.02,21.325,21.325,65.11,HBH,-1.583,0.205827,0.000925438,0.572581 Ubiquitin_I61H,Ubiquitin_61,Uba1,Ubiquitin,P0CG48,0.572581,NO,61,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.514,-4.892,3.378,5.19922,0.038,,B,1,-0.76,1.953,,24.53,PHP,-1.70833,0.205827,0.000738268,0.572581 Ubiquitin_I61K,Ubiquitin_61,Uba1,Ubiquitin,P0CG48,0.572581,NO,61,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.514,-3.727,2.213,5.19922,0.038,,B,1,-0.76,1.953,,24.53,PHP,-1.70833,0.205827,0.000738268,0.572581 Ubiquitin_L67Y,Ubiquitin_67,Uba1,Ubiquitin,P0CG48,0.572581,NO,67,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.435,-4.057,2.622,4.92156,,E,B,1.19,-1.02,6.371,6.371,30.8,PHB,-1.628,0.205827,0.000482727,0.572581 beta-lactamase_0_A170E,beta-lactamase_0_170,TEM-1,beta-lactamase_0,P62593,0.572714,NO,170,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.237,-3.626,2.389,,0.126,,L,0.46,-0.35,2.427,,64.69,AHH,-1.63267,0.0500837,0.00431903,0.572714 beta-lactamase_2500_I258F,beta-lactamase_2500_258,TEM-1,beta-lactamase_2500,P62593,0.572767,NO,258,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.361275,0.007931,0.572767 kka2_1:4_Q27Y,kka2_1:4_27,Kka2,kka2_1:4,P00552,0.572875,NO,27,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-1.659,-4.273,2.614,,0.608,,A,0.4,0.71,1.498,,65.53,PPP,-1.90733,0.168804,0.00595365,0.572875 kka2_1:4_S204I,kka2_1:4_204,Kka2,kka2_1:4,P00552,0.572914,NO,204,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.353,-3.845,2.492,,0.144,E,A,0.27,-1.2,2.442,,65.53,HPO,-0.953333,0.168804,0.00881794,0.572914 kka2_1:2_R122D,kka2_1:2_122,Kka2,kka2_1:2,P00552,0.572949,NO,122,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.175,-2.452,0.277,,0.487,H,A,1.2,0.26,16.436,16.436,71.59,BBH,-1.53833,0.295029,0.00736512,0.572949 kka2_1:1_L81K,kka2_1:1_81,Kka2,kka2_1:1,P00552,0.572961,NO,81,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.427,-3.851,2.424,,0.46,E,A,0.55,-0.14,0.374,,63.64,HHA,-1.50567,0.520039,0.00805839,0.572961 kka2_1:2_V186G,kka2_1:2_186,Kka2,kka2_1:2,P00552,0.573019,NO,186,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.011,-3.743,2.732,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.295029,0.00409703,0.573019 kka2_1:1_C77G,kka2_1:1_77,Kka2,kka2_1:1,P00552,0.573102,NO,77,C,G,CG,Special,Special,5.07,3.29388,-1.77612,159,121,75,-46,108.5,60.1,-48.4,-1.477,-2.097,0.62,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.520039,0.00441216,0.573102 kka2_1:2_I254D,kka2_1:2_254,Kka2,kka2_1:2,P00552,0.573124,NO,254,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.933,-4.156,2.223,,0.135,H,A,1.52,-0.6,2.562,,71.59,BHH,-1.668,0.295029,0.0132375,0.573124 beta-lactamase_N134Y,beta-lactamase_134,TEM-1,beta-lactamase,P62593,0.573172,NO,134,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-0.879,-4.188,3.309,5.07245,0.138,H,A,0.09,-0.6,1.441,,53.15,HPH,-1.02233,0.221079,0.000644786,0.573172 beta-lactamase_156_W227S,beta-lactamase_156_227,TEM-1,beta-lactamase_156,P62593,0.573225,NO,227,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-0.982,-3.768,2.786,,0.272,,B,0.47,-0.29,2.533,,74.48,OHH,-1.595,0.111618,0.00226019,0.573225 beta-lactamase_2500_F70G,beta-lactamase_2500_70,TEM-1,beta-lactamase_2500,P62593,0.573316,NO,70,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.169,-3.574,2.405,,,H,A,0.58,-1.34,1.918,,63.99,PHB,-0.980667,0.361275,0.00193499,0.573316 beta-lactamase_0_S128R,beta-lactamase_0_128,TEM-1,beta-lactamase_0,P62593,0.573337,NO,128,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-0.84,-3.708,2.868,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.0500837,0.00071483,0.573337 beta-lactamase_0_P250F,beta-lactamase_0_250,TEM-1,beta-lactamase_0,P62593,0.573401,NO,250,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.0500837,0.00550899,0.573401 beta-lactamase_0_M115H,beta-lactamase_0_115,TEM-1,beta-lactamase_0,P62593,0.573462,NO,115,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.389,-4.759,3.37,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.0500837,0.0034337,0.573462 beta-lactamase_39_K232A,beta-lactamase_39_232,TEM-1,beta-lactamase_39,P62593,0.573568,NO,232,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.012,-3.12,2.108,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.0495842,0.00313441,0.573568 beta-lactamase_T69I,beta-lactamase_69,TEM-1,beta-lactamase,P62593,0.573647,NO,69,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-0.973,-3.64,2.667,5.16042,,G,A,0.69,-1.24,0.505,,93.01,PPH,-1.01833,0.221079,0.00127498,0.573647 beta-lactamase_156_F58D,beta-lactamase_156_58,TEM-1,beta-lactamase_156,P62593,0.573728,NO,58,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-2.914,-3.846,0.932,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.111618,0.00523369,0.573728 beta-lactamase_156_L167H,beta-lactamase_156_167,TEM-1,beta-lactamase_156,P62593,0.573728,NO,167,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.138,-4.852,3.714,,0.015,G,A,0.55,-0.63,0.4,,64.69,AHP,-1.30767,0.111618,0.00303566,0.573728 beta-lactamase_T178I,beta-lactamase_178,TEM-1,beta-lactamase,P62593,0.573805,NO,178,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-0.791,-3.56,2.769,5.06452,0.029,E,B,0.3,-1.07,,,,APP,-0.947667,0.221079,0.000684366,0.573805 kka2_1:2_S204L,kka2_1:2_204,Kka2,kka2_1:2,P00552,0.573854,NO,204,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.353,-3.418,2.065,,0.144,E,A,0.27,-1.2,2.442,,65.53,HPO,-0.953333,0.295029,0.00881794,0.573854 kka2_1:1_D216V,kka2_1:1_216,Kka2,kka2_1:1,P00552,0.573907,NO,216,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.785,-3.805,3.02,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.520039,0.00229969,0.573907 beta-lactamase_39_I261Q,beta-lactamase_39_261,TEM-1,beta-lactamase_39,P62593,0.573951,NO,261,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.0495842,0.0123091,0.573951 Pab1_I152A,Pab1_152,Pab1,Pab1,P04147,0.573975,NO,152,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.345,-2.891,1.546,,0.165,E,B,1.23,-0.71,1.288,,71.4,AHH,-1.59433,0.175299,0.000740963,0.573975 kka2_1:4_R38M,kka2_1:4_38,Kka2,kka2_1:4,P00552,0.573999,NO,38,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.207,-3.078,1.871,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.168804,0.00372499,0.573999 kka2_1:4_L193A,kka2_1:4_193,Kka2,kka2_1:4,P00552,0.574027,NO,193,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.983,-3.189,2.206,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.168804,0.00480179,0.574027 kka2_1:8_R44I,kka2_1:8_44,Kka2,kka2_1:8,P00552,0.574033,NO,44,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.062,-4.031,1.969,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.100394,0.00745043,0.574033 kka2_1:8_R44I,kka2_1:8_44,Kka2,kka2_1:8,P00552,0.574033,NO,44,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.062,-4.031,1.969,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.100394,0.00745043,0.574033 beta-lactamase_2500_P224S,beta-lactamase_2500_224,TEM-1,beta-lactamase_2500,P62593,0.574067,NO,224,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.893,-2.58,1.687,,0.383,,B,0.52,-0.3,2.666,,74.48,HOH,-1.26433,0.361275,0.00189564,0.574067 beta-lactamase_0_D174F,beta-lactamase_0_174,TEM-1,beta-lactamase_0,P62593,0.574199,NO,174,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.738,-4.292,3.554,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.0500837,0.00125633,0.574199 beta-lactamase_D48R,beta-lactamase_48,TEM-1,beta-lactamase,P62593,0.574254,NO,48,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.101,-3.84,2.739,4.89966,0.189,E,B,0.23,0.21,1.281,,50.35,HAH,-1.62467,0.221079,0.0027273,0.574254 kka2_1:1_L223M,kka2_1:1_223,Kka2,kka2_1:1,P00552,0.574328,NO,223,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.861,-3.916,3.055,,,H,A,0.55,-1.24,1.268,,50,HHH,-0.854333,0.520039,0.00253574,0.574328 kka2_1:2_R253A,kka2_1:2_253,Kka2,kka2_1:2,P00552,0.574343,NO,253,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.356,-2.382,1.026,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.295029,0.0144195,0.574343 gb1_A249H,gb1_249,gb1,gb1,P06654,0.574378,NO,249,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.739,-4.614,2.875,,,,,,,0.252,,44.87,AHH,-1.67367,0.177985,0.00333585,0.574378 beta-lactamase_2500_I140C,beta-lactamase_2500_140,TEM-1,beta-lactamase_2500,P62593,0.574434,NO,140,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.733,-4.792,3.059,,0.128,H,A,0.48,0.41,1.628,,73.08,PHO,-1.48733,0.361275,0.00597777,0.574434 kka2_1:4_P128C,kka2_1:4_128,Kka2,kka2_1:4,P00552,0.574498,NO,128,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.922,-4.968,3.046,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.168804,0.00774689,0.574498 kka2_1:2_D261V,kka2_1:2_261,Kka2,kka2_1:2,P00552,0.57451,NO,261,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.708,-3.782,3.074,,0.146,G,A,0.75,-0.33,,,,HAA,-0.759333,0.295029,0.0224846,0.57451 beta-lactamase_I278C,beta-lactamase_278,TEM-1,beta-lactamase,P62593,0.574678,NO,278,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.348,-4.777,3.429,5.35127,0.015,H,A,0.77,-0.85,2.718,,63.29,AHO,-1.41833,0.221079,0.0310297,0.574678 kka2_1:1_D90Y,kka2_1:1_90,Kka2,kka2_1:1,P00552,0.574681,NO,90,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.459,-3.217,0.758,,0.104,E,B,0.75,0.73,6.085,,64.39,BAH,-1.72833,0.520039,0.00583842,0.574681 Pab1_N192P,Pab1_192,Pab1,Pab1,P04147,0.574695,NO,192,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-1.079,-3.697,2.618,,0.619,T,l,,2.28,,,,HPO,-1.231,0.175299,0.000273498,0.574695 kka2_1:2_V97M,kka2_1:2_97,Kka2,kka2_1:2,P00552,0.574773,NO,97,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.453,-2.867,1.414,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.295029,0.00737869,0.574773 beta-lactamase_2500_T179M,beta-lactamase_2500_179,TEM-1,beta-lactamase_2500,P62593,0.574798,NO,179,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.085,-4.564,3.479,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.361275,0.00226045,0.574798 beta-lactamase_0_W227Y,beta-lactamase_0_227,TEM-1,beta-lactamase_0,P62593,0.574811,NO,227,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-0.982,-3.356,2.374,,0.272,,B,0.47,-0.29,3.782,,74.48,OHH,-1.595,0.0500837,0.00226019,0.574811 beta-lactamase_2500_R59Q,beta-lactamase_2500_59,TEM-1,beta-lactamase_2500,P62593,0.574866,NO,59,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.345,-2.612,1.267,,0.329,S,L,1.2,-0.09,3.719,,73.08,HBO,-2.24267,0.361275,0.00318082,0.574866 beta-lactamase_G226V,beta-lactamase_226,TEM-1,beta-lactamase,P62593,0.574891,NO,226,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.461,-3.807,2.346,5.70682,0.701,T,l,0.77,-0.25,3.199,,74.48,HOH,-1.42933,0.221079,0.00665294,0.574891 kka2_1:2_M120T,kka2_1:2_120,Kka2,kka2_1:2,P00552,0.574999,NO,120,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-3.877,-3.448,-0.429,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.295029,0.00265808,0.574999 beta-lactamase_625_R242C,beta-lactamase_625_242,TEM-1,beta-lactamase_625,P62593,0.57503,NO,242,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.213352,0.00452879,0.57503 kka2_1:2_A78Q,kka2_1:2_78,Kka2,kka2_1:2,P00552,0.575085,NO,78,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.744,-3.972,2.228,,0.078,.,B,0.46,-0.53,0.206,,56.06,OHH,-1.863,0.295029,0.00457299,0.575085 beta-lactamase_2500_L89Y,beta-lactamase_2500_89,TEM-1,beta-lactamase_2500,P62593,0.575172,NO,89,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.096,-4.101,3.005,,0.168,T,A,0.55,0.63,2.066,,64.34,PHO,-1.75767,0.361275,0.00207068,0.575172 kka2_1:1_A108G,kka2_1:1_108,Kka2,kka2_1:1,P00552,0.5752,NO,108,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.061,-2.917,0.856,,0.243,.,B,0.46,-1.34,3.156,,71.59,HHO,-1.57033,0.520039,0.00751209,0.5752 beta-lactamase_625_L49K,beta-lactamase_625_49,TEM-1,beta-lactamase_625,P62593,0.575304,NO,49,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.897,-3.583,1.686,,0.131,T,A,0.55,0.04,3.112,,64.69,AHP,-1.99233,0.213352,0.00401477,0.575304 beta-lactamase_625_L135H,beta-lactamase_625_135,TEM-1,beta-lactamase_625,P62593,0.575308,NO,135,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.002,-4.934,3.932,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.213352,0.00244423,0.575308 beta-lactamase_0_A170D,beta-lactamase_0_170,TEM-1,beta-lactamase_0,P62593,0.575352,NO,170,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.237,-3.712,2.475,,0.126,,L,0.46,-0.35,2.427,,64.69,AHH,-1.63267,0.0500837,0.00431903,0.575352 Pab1_I128H,Pab1_128,Pab1,Pab1,P04147,0.575381,NO,128,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.345,-4.798,3.453,,0.008,E,B,1.68,-0.6,1.706,,78.68,PHH,-1.231,0.175299,0.00104192,0.575381 kka2_1:4_L212T,kka2_1:4_212,Kka2,kka2_1:4,P00552,0.575399,NO,212,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.904,-3.451,2.547,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.168804,0.0031426,0.575399 kka2_1:1_E86D,kka2_1:1_86,Kka2,kka2_1:1,P00552,0.575441,NO,86,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.86,-1.985,0.125,,0.369,.,B,1.04,1.92,18.506,18.506,63.26,PAH,-1.98067,0.520039,0.00642858,0.575441 beta-lactamase_R241V,beta-lactamase_241,TEM-1,beta-lactamase,P62593,0.575442,NO,241,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.433,-3.571,2.138,5.02621,0.094,E,B,0.68,-0.16,1.327,,50,PBO,-1.42967,0.221079,0.00452736,0.575442 kka2_1:1_L103P,kka2_1:1_103,Kka2,kka2_1:1,P00552,0.575534,NO,103,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-2.362,-3.937,1.575,,0.394,T,A,0.55,-0.99,4.121,,63.64,HHP,-1.534,0.520039,0.00574792,0.575534 Pab1_K166P,Pab1_166,Pab1,Pab1,P04147,0.575604,NO,166,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.262,-3.615,2.353,,0.299,,l,,0,,,,PBO,-1.21033,0.175299,0.0011038,0.575604 kka2_1:4_L107Y,kka2_1:4_107,Kka2,kka2_1:4,P00552,0.575653,NO,107,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.238,-4.146,2.908,,0.197,.,B,0.55,-1.1,0.398,,71.59,BHH,-2.143,0.168804,0.00561937,0.575653 kka2_1:1_F206L,kka2_1:1_206,Kka2,kka2_1:1,P00552,0.575765,NO,206,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.349,-2.335,0.986,,0.006,E,B,0.58,-1.21,0.978,,63.64,OHH,-1.04,0.520039,0.00936868,0.575765 beta-lactamase_156_W288G,beta-lactamase_156_288,TEM-1,beta-lactamase_156,P62593,0.575842,NO,288,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,,,,,,,,,,,,,BHO,,0.111618,,0.575842 beta-lactamase_2500_D231A,beta-lactamase_2500_231,TEM-1,beta-lactamase_2500,P62593,0.575851,NO,231,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.816,-3.3,2.484,,,E,B,0.75,-1.06,0.319,,65.38,HAB,-0.994,0.361275,0.00107395,0.575851 kka2_1:1_C192S,kka2_1:1_192,Kka2,kka2_1:1,P00552,0.575862,NO,192,C,S,CS,Special,Polar,5.07,5.68,0.61,112,121,105,-16,108.5,89,-19.5,-1.067,-2.445,1.378,,0.095,.,B,0.46,-0.75,2.749,,50,HOH,-0.960333,0.520039,0.00485428,0.575862 kka2_1:2_A64T,kka2_1:2_64,Kka2,kka2_1:2,P00552,0.575889,NO,64,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.496,-2.834,1.338,,0.039,H,A,0.46,-0.57,14.509,14.509,56.06,AHH,-1.334,0.295029,0.00705578,0.575889 beta-lactamase_2500_D212T,beta-lactamase_2500_212,TEM-1,beta-lactamase_2500,P62593,0.575931,NO,212,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.624,-2.54,0.916,,0.037,,b,0.75,-0.58,12.482,,74.48,HAB,-1.77667,0.361275,0.00644302,0.575931 beta-lactamase_0_E119N,beta-lactamase_0_119,TEM-1,beta-lactamase_0,P62593,0.575942,NO,119,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.412,-3.591,2.179,,0.358,H,A,1.04,0.51,3.396,,63.99,BAH,-1.623,0.0500837,0.00386966,0.575942 kka2_1:1_D190A,kka2_1:1_190,Kka2,kka2_1:1,P00552,0.575983,NO,190,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.708,-3.331,2.623,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.520039,0.00247989,0.575983 beta-lactamase_G142R,beta-lactamase_142,TEM-1,beta-lactamase,P62593,0.576005,NO,142,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.707,-3.93,3.223,4.55474,0.034,,p,0.77,-0.64,1.947,,64.69,OOO,-0.834,0.221079,0.00060149,0.576005 beta-lactamase_625_T178I,beta-lactamase_625_178,TEM-1,beta-lactamase_625,P62593,0.576042,NO,178,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-0.791,-3.56,2.769,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.213352,0.000684366,0.576042 kka2_1:2_R38H,kka2_1:2_38,Kka2,kka2_1:2,P00552,0.576042,NO,38,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.207,-4.545,3.338,,0.355,E,B,1.2,-1.13,6.872,6.872,52.27,HBH,-1.28567,0.295029,0.00372499,0.576042 beta-lactamase_2500_P105V,beta-lactamase_2500_105,TEM-1,beta-lactamase_2500,P62593,0.576097,NO,105,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.813,-3.554,2.741,,0.226,T,A,0.52,0.8,3.1,,63.29,POH,-1.01533,0.361275,0.0011981,0.576097 beta-lactamase_M115F,beta-lactamase_115,TEM-1,beta-lactamase,P62593,0.576169,NO,115,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.389,-2.82,1.431,4.89743,0.019,E,B,1.3,0.08,1.236,,69.58,OHP,-1.25433,0.221079,0.0034337,0.576169 kka2_1:1_R202H,kka2_1:1_202,Kka2,kka2_1:1,P00552,0.576186,NO,202,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.761,-2.934,1.173,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.520039,0.00696498,0.576186 kka2_1:1_T85C,kka2_1:1_85,Kka2,kka2_1:1,P00552,0.576253,NO,85,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.165,-5.123,2.958,,0.576,E,B,0.82,1.39,16.653,16.653,71.59,HPA,-2.10133,0.520039,0.00634493,0.576253 beta-lactamase_0_D48Y,beta-lactamase_0_48,TEM-1,beta-lactamase_0,P62593,0.576268,NO,48,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.101,-4.182,3.081,,0.189,E,B,0.75,0.21,17.825,17.825,50.35,HAH,-1.62467,0.0500837,0.0027273,0.576268 kka2_1:4_G189V,kka2_1:4_189,Kka2,kka2_1:4,P00552,0.576286,NO,189,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.596,-3.782,3.186,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.168804,0.00253688,0.576286 WW_domain_Q186T,WW_domain_186,Yap65,WW_domain,P46937,0.576336,NO,186,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-1.358,-3.198,1.84,4.88854,,,,,,,,,OPB,-1.207,0.153962,0.00161546,0.576336 beta-lactamase_L73D,beta-lactamase_73,TEM-1,beta-lactamase,P62593,0.576391,NO,73,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.507,-4.091,2.584,5.84139,,H,A,1.75,-0.64,2.09,,67.83,HHH,-1.487,0.221079,0.00488983,0.576391 kka2_1:2_A215C,kka2_1:2_215,Kka2,kka2_1:2,P00552,0.576393,NO,215,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.968,-4.591,3.623,,0.039,E,B,0.46,-0.59,2.137,,50.38,HHA,-1.00467,0.295029,0.00529129,0.576393 beta-lactamase_R59W,beta-lactamase_59,TEM-1,beta-lactamase,P62593,0.576411,NO,59,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.345,-5.421,4.076,5.49837,0.329,S,L,0.68,-0.09,1.806,,73.08,HBO,-2.24267,0.221079,0.00318082,0.576411 beta-lactamase_N134I,beta-lactamase_134,TEM-1,beta-lactamase,P62593,0.576426,NO,134,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-0.879,-4.036,3.157,5.07245,0.138,H,A,0.09,-0.6,1.441,,53.15,HPH,-1.02233,0.221079,0.000644786,0.576426 kka2_1:4_L94S,kka2_1:4_94,Kka2,kka2_1:4,P00552,0.576426,NO,94,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.618,-3.596,1.978,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.168804,0.00520888,0.576426 kka2_1:2_E199I,kka2_1:2_199,Kka2,kka2_1:2,P00552,0.576442,NO,199,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.234,-3.975,1.741,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.295029,0.00854122,0.576442 beta-lactamase_I259A,beta-lactamase_259,TEM-1,beta-lactamase,P62593,0.576522,NO,259,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.522,-2.368,0.846,5.28457,,E,B,1,-0.8,1.24,,64.34,HHH,-1.53267,0.221079,0.0070773,0.576522 PSD95pdz3_A375N,PSD95pdz3_375,PSD95pdz3,PSD95pdz3,P31016,0.576528,NO,375,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.307,-3.58,2.273,5.05512,,,,,13.888,,,,PHH,-1.43767,0.0758425,0.000356809,0.576528 beta-lactamase_L191S,beta-lactamase_191,TEM-1,beta-lactamase,P62593,0.576703,NO,191,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.087,-3.562,2.475,5.72226,,H,A,1.07,0.09,1.23,,63.29,BHH,-1.445,0.221079,0.00263549,0.576703 beta-lactamase_R59L,beta-lactamase_59,TEM-1,beta-lactamase,P62593,0.57675,NO,59,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.345,-3.484,2.139,5.49837,0.329,S,L,0.68,-0.09,1.806,,73.08,HBO,-2.24267,0.221079,0.00318082,0.57675 beta-lactamase_0_D48F,beta-lactamase_0_48,TEM-1,beta-lactamase_0,P62593,0.576796,NO,48,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.101,-4.285,3.184,,0.189,E,B,0.75,0.21,17.825,17.825,50.35,HAH,-1.62467,0.0500837,0.0027273,0.576796 beta-lactamase_I140H,beta-lactamase_140,TEM-1,beta-lactamase,P62593,0.576862,NO,140,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.733,-4.991,3.258,5.29918,0.128,H,A,1,0.41,1.16,,73.08,PHO,-1.48733,0.221079,0.00597777,0.576862 kka2_1:1_L174P,kka2_1:1_174,Kka2,kka2_1:1,P00552,0.576927,NO,174,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.952,-4.115,3.163,,,H,A,0.55,-0.31,13.276,13.276,51.89,BHB,-2.08533,0.520039,0.00438501,0.576927 beta-lactamase_2500_W208Y,beta-lactamase_2500_208,TEM-1,beta-lactamase_2500,P62593,0.577062,NO,208,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-0.818,-3.262,2.444,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.361275,0.00126609,0.577062 beta-lactamase_39_V72Y,beta-lactamase_39_72,TEM-1,beta-lactamase_39,P62593,0.577206,NO,72,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.658,-4.055,2.397,,,H,A,0.44,-1.03,1.92,,65.73,BHH,-1.32167,0.0495842,0.00501194,0.577206 beta-lactamase_0_G141I,beta-lactamase_0_141,TEM-1,beta-lactamase_0,P62593,0.577216,NO,141,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.828,-4.236,3.408,,0.575,T,l,0.29,-0.28,0.722,,64.69,HOO,-1.08933,0.0500837,0.0012419,0.577216 kka2_1:8_H135F,kka2_1:8_135,Kka2,kka2_1:8,P00552,0.577237,NO,135,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-1.331,-4.11,2.779,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.100394,0.00532566,0.577237 kka2_1:8_H135F,kka2_1:8_135,Kka2,kka2_1:8,P00552,0.577237,NO,135,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-1.331,-4.11,2.779,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.100394,0.00532566,0.577237 beta-lactamase_625_D83R,beta-lactamase_625_83,TEM-1,beta-lactamase_625,P62593,0.577355,NO,83,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.066,-3.889,2.823,,0.354,H,A,0.75,0.22,0.239,,48.95,HAH,-1.34733,0.213352,0.00205968,0.577355 beta-lactamase_39_I125E,beta-lactamase_39_125,TEM-1,beta-lactamase_39,P62593,0.577373,NO,125,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.441,-3.878,2.437,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.0495842,0.00383964,0.577373 beta-lactamase_2500_T27K,beta-lactamase_2500_27,TEM-1,beta-lactamase_2500,P62593,0.57741,NO,27,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.905,-3.516,1.611,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.361275,0.00306559,0.57741 beta-lactamase_L188H,beta-lactamase_188,TEM-1,beta-lactamase,P62593,0.577485,NO,188,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.166,-4.872,3.706,5.55434,,H,A,1.07,-0.3,1.574,,60.14,PHB,-1.47033,0.221079,0.00295687,0.577485 PSD95pdz3_I338P,PSD95pdz3_338,PSD95pdz3,PSD95pdz3,P31016,0.577625,NO,338,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.63,-3.786,2.156,5.45113,,,,,13.0087,,,,HHP,-1.55767,0.0758425,0.000862587,0.577625 beta-lactamase_H151P,beta-lactamase_151,TEM-1,beta-lactamase,P62593,0.577636,NO,151,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-2.96,-3.911,0.951,5.47408,0.594,H,A,0.35,0.1,1.843,,77.62,HBP,-2.34767,0.221079,0.00216946,0.577636 kka2_1:1_V84L,kka2_1:1_84,Kka2,kka2_1:1,P00552,0.577637,NO,84,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-2.279,-2.527,0.248,,0.258,E,B,0.44,1.03,3.484,,71.59,HHP,-2.337,0.520039,0.00724019,0.577637 kka2_1:2_K138W,kka2_1:2_138,Kka2,kka2_1:2,P00552,0.577706,NO,138,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-2.5,-5.6,3.1,,0.594,H,A,2.34,0.98,21.038,21.038,71.59,HBB,-2.48833,0.295029,0.00628542,0.577706 beta-lactamase_0_S128I,beta-lactamase_0_128,TEM-1,beta-lactamase_0,P62593,0.577784,NO,128,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-0.84,-3.785,2.945,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.0500837,0.00071483,0.577784 kka2_1:2_A191T,kka2_1:2_191,Kka2,kka2_1:2,P00552,0.577786,NO,191,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.831,-3.288,2.457,,,.,b,0.46,-0.94,2.046,,50,AHO,-0.868667,0.295029,0.00338807,0.577786 kka2_1:2_R66L,kka2_1:2_66,Kka2,kka2_1:2,P00552,0.577892,NO,66,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-0.922,-3.421,2.499,,0.103,H,A,1.2,-0.2,2.659,,46.21,HBH,-1.13567,0.295029,0.00161025,0.577892 beta-lactamase_2500_M270R,beta-lactamase_2500_270,TEM-1,beta-lactamase_2500,P62593,0.5779,NO,270,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.723,,,,0.422,H,A,1.59,1.15,2.029,,64.34,PHA,-1.70933,0.361275,0.00767762,0.5779 beta-lactamase_39_S241W,beta-lactamase_39_241,TEM-1,beta-lactamase_39,P62593,0.577921,NO,241,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.0495842,0.00452736,0.577921 kka2_1:4_M197K,kka2_1:4_197,Kka2,kka2_1:4,P00552,0.577936,NO,197,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.707,-3.81,2.103,,0.121,E,B,0.55,-1.19,0.415,,65.53,HHH,-1.847,0.168804,0.00921295,0.577936 beta-lactamase_156_E119F,beta-lactamase_156_119,TEM-1,beta-lactamase_156,P62593,0.57794,NO,119,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.412,-4.398,2.986,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.111618,0.00386966,0.57794 beta-lactamase_R176P,beta-lactamase_176,TEM-1,beta-lactamase,P62593,0.57795,NO,176,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-0.863,-3.88,3.017,5.61264,0.385,T,B,0.68,-0.63,,,,ABA,-1.38867,0.221079,0.00105554,0.57795 kka2_1:2_T85L,kka2_1:2_85,Kka2,kka2_1:2,P00552,0.57798,NO,85,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.165,-2.782,0.617,,0.576,E,B,0.22,1.39,1.853,,71.59,HPA,-2.10133,0.295029,0.00634493,0.57798 kka2_1:2_S105Q,kka2_1:2_105,Kka2,kka2_1:2,P00552,0.578,NO,105,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.945,-3.245,1.3,,0.056,S,B,0.27,-1.04,3.442,,65.53,PPB,-2.17033,0.295029,0.00847233,0.578 kka2_1:1_Q100E,kka2_1:1_100,Kka2,kka2_1:1,P00552,0.578056,NO,100,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.77,-2.743,-0.027,,0.646,E,B,0.4,-0.79,15.116,15.116,71.59,OPA,-1.46467,0.520039,0.0066405,0.578056 kka2_1:8_D208N,kka2_1:8_208,Kka2,kka2_1:8,P00552,0.578097,NO,208,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.708,-3.251,2.543,,0.36,,l,0.29,-1.01,,,,HAO,-0.929667,0.100394,0.00212588,0.578097 kka2_1:8_D208N,kka2_1:8_208,Kka2,kka2_1:8,P00552,0.578097,NO,208,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.708,-3.251,2.543,,0.36,,l,0.29,-1.01,,,,HAO,-0.929667,0.100394,0.00212588,0.578097 beta-lactamase_2500_R176W,beta-lactamase_2500_176,TEM-1,beta-lactamase_2500,P62593,0.578149,NO,176,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-0.863,-5.322,4.459,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.361275,0.00105554,0.578149 beta-lactamase_625_A235C,beta-lactamase_625_235,TEM-1,beta-lactamase_625,P62593,0.578183,NO,235,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.266,-4.693,3.427,,0.32,E,B,0.46,-0.86,0.281,,50,OHO,-0.89,0.213352,0.00493474,0.578183 beta-lactamase_A23Y,beta-lactamase_23,TEM-1,beta-lactamase,P62593,0.578366,NO,23,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.548,-4.002,2.454,,,,,,,0.801,,93.01,HHB,-2.235,0.221079,0.00245563,0.578366 beta-lactamase_G114Q,beta-lactamase_114,TEM-1,beta-lactamase,P62593,0.578366,NO,114,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.094,-4.039,2.945,4.92659,0.011,,p,0.77,0.35,2.148,,41.61,AOH,-1.43733,0.221079,0.00224919,0.578366 beta-lactamase_L100E,beta-lactamase_100,TEM-1,beta-lactamase,P62593,0.578366,NO,100,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.218,-3.935,2.717,5.60291,0.343,,B,1.3,0.13,1.173,,63.29,AHH,-1.23467,0.221079,0.00413885,0.578366 beta-lactamase_L10E,beta-lactamase_10,TEM-1,beta-lactamase,P62593,0.578366,NO,10,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.623,-3.753,2.13,,,,,,,2.467,,65.38,HHH,-1.83833,0.221079,0.00296968,0.578366 beta-lactamase_P143L,beta-lactamase_143,TEM-1,beta-lactamase,P62593,0.578366,NO,143,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.967,-2.577,1.61,5.16366,0.075,H,A,0.99,-0.37,0.479,,66.78,OOB,-1.354,0.221079,0.00114551,0.578366 kka2_1:8_R217H,kka2_1:8_217,Kka2,kka2_1:8,P00552,0.578394,NO,217,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.158,-4.518,3.36,,0.252,T,A,0.16,-0.59,1.151,,52.27,ABH,-1.127,0.100394,0.0047191,0.578394 kka2_1:8_R217H,kka2_1:8_217,Kka2,kka2_1:8,P00552,0.578394,NO,217,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.158,-4.518,3.36,,0.252,T,A,0.16,-0.59,1.151,,52.27,ABH,-1.127,0.100394,0.0047191,0.578394 kka2_1:1_R239S,kka2_1:1_239,Kka2,kka2_1:1,P00552,0.578446,NO,239,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.949,-2.753,-0.196,,0.15,H,A,1.2,-0.31,0.477,,71.59,ABH,-2.23,0.520039,0.00835326,0.578446 kka2_1:2_L184W,kka2_1:2_184,Kka2,kka2_1:2,P00552,0.57847,NO,184,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.496,-3.533,2.037,,0.489,E,B,0.55,-0.06,14.044,14.044,63.26,AHH,-1.24833,0.295029,0.00518742,0.57847 beta-lactamase_0_I171V,beta-lactamase_0_171,TEM-1,beta-lactamase_0,P62593,0.578481,NO,171,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-2.431,-3.274,0.843,,0.361,,B,0.48,0.53,16.954,16.954,77.62,HHO,-1.55533,0.0500837,0.00623355,0.578481 kka2_1:1_H124Y,kka2_1:1_124,Kka2,kka2_1:1,P00552,0.578484,NO,124,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-0.84,-3.291,2.451,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.520039,0.00211296,0.578484 kka2_1:2_E169L,kka2_1:2_169,Kka2,kka2_1:2,P00552,0.578507,NO,169,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.996,-3.06,1.064,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.295029,0.00730086,0.578507 kka2_1:1_S251G,kka2_1:1_251,Kka2,kka2_1:1,P00552,0.578584,NO,251,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.636,-2.736,0.1,,0.712,H,A,0.27,-0.25,1.356,,71.59,APP,-2.09367,0.520039,0.0138916,0.578584 beta-lactamase_2500_R81I,beta-lactamase_2500_81,TEM-1,beta-lactamase_2500,P62593,0.578591,NO,81,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.466,-4.004,2.538,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.361275,0.00499763,0.578591 kka2_1:8_E63K,kka2_1:8_63,Kka2,kka2_1:8,P00552,0.578631,NO,63,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-0.762,-3.035,2.273,,0.043,H,A,1.52,-0.43,,,,AAH,-1.283,0.100394,0.00118399,0.578631 kka2_1:8_E63K,kka2_1:8_63,Kka2,kka2_1:8,P00552,0.578631,NO,63,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-0.762,-3.035,2.273,,0.043,H,A,1.52,-0.43,,,,AAH,-1.283,0.100394,0.00118399,0.578631 kka2_1:4_D62M,kka2_1:4_62,Kka2,kka2_1:4,P00552,0.578638,NO,62,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.591,-4.884,3.293,,0.262,H,A,0.29,0.08,14.756,14.756,64.39,PAA,-1.77833,0.168804,0.00744243,0.578638 beta-lactamase_156_T178F,beta-lactamase_156_178,TEM-1,beta-lactamase_156,P62593,0.578773,NO,178,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-0.791,-4.067,3.276,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.111618,0.000684366,0.578773 gb1_K254P,gb1_254,gb1,gb1,P06654,0.578848,NO,254,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.748,-3.52,1.772,,,,,,,1.793,,37.28,ABH,-2.195,0.177985,0.00622711,0.578848 kka2_1:2_G164S,kka2_1:2_164,Kka2,kka2_1:2,P00552,0.578874,NO,164,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.869,-2.388,1.519,,0.862,T,l,0.75,1.45,1.539,,64.39,POH,-1.828,0.295029,0.00442091,0.578874 beta-lactamase_D83C,beta-lactamase_83,TEM-1,beta-lactamase,P62593,0.5789,NO,83,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.066,-5.147,4.081,5.40616,0.354,H,A,1.33,0.22,0.861,,48.95,HAH,-1.34733,0.221079,0.00205968,0.5789 beta-lactamase_I229Y,beta-lactamase_229,TEM-1,beta-lactamase,P62593,0.578924,NO,229,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.267,-4.04,2.773,5.0911,0.083,E,B,1,-0.76,1.114,,50,HHH,-1.58767,0.221079,0.00477249,0.578924 beta-lactamase_2500_F228C,beta-lactamase_2500_228,TEM-1,beta-lactamase_2500,P62593,0.57894,NO,228,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-2.342,-5.075,2.733,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.361275,0.0046669,0.57894 beta-lactamase_625_I93E,beta-lactamase_625_93,TEM-1,beta-lactamase_625,P62593,0.579061,NO,93,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.401,-3.886,2.485,,0.128,E,B,0.48,0.44,1.524,,67.83,BHB,-1.873,0.213352,0.00527066,0.579061 beta-lactamase_T187E,beta-lactamase_187,TEM-1,beta-lactamase,P62593,0.579084,NO,187,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.401,-3.52,2.119,5.11453,0.007,H,A,0.3,-1.19,1.751,,67.48,PPH,-1.69633,0.221079,0.00491782,0.579084 kka2_1:1_V186L,kka2_1:1_186,Kka2,kka2_1:1,P00552,0.57909,NO,186,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.011,-2.323,1.312,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.520039,0.00409703,0.57909 kka2_1:1_E199V,kka2_1:1_199,Kka2,kka2_1:1,P00552,0.579104,NO,199,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.234,-2.91,0.676,,0.508,E,B,1.04,-0.43,3.012,,65.53,HAP,-2.133,0.520039,0.00854122,0.579104 kka2_1:8_L170C,kka2_1:8_170,Kka2,kka2_1:8,P00552,0.579122,NO,170,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.28,-4.755,3.475,,0.029,H,A,1.59,0.11,1.453,,62.5,AHH,-1.534,0.100394,0.00730791,0.579122 kka2_1:8_L170C,kka2_1:8_170,Kka2,kka2_1:8,P00552,0.579122,NO,170,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.28,-4.755,3.475,,0.029,H,A,1.59,0.11,1.453,,62.5,AHH,-1.534,0.100394,0.00730791,0.579122 kka2_1:2_F203S,kka2_1:2_203,Kka2,kka2_1:2,P00552,0.579219,NO,203,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-0.911,-3.673,2.762,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.295029,0.00318738,0.579219 Pab1_G150N,Pab1_150,Pab1,Pab1,P04147,0.57942,NO,150,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.809,-3.265,2.456,,0.287,S,b,0.23,0.53,,,,HOA,-1.45233,0.175299,0.000323835,0.57942 beta-lactamase_2500_L28N,beta-lactamase_2500_28,TEM-1,beta-lactamase_2500,P62593,0.579533,NO,28,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.579,-4.056,2.477,,0.277,H,A,0.55,-0.16,2.716,,93.01,PHH,-2.11333,0.361275,0.00359321,0.579533 kka2_1:4_A215E,kka2_1:4_215,Kka2,kka2_1:4,P00552,0.579557,NO,215,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.968,-3.495,2.527,,0.039,E,B,0.46,-0.59,0.754,,50.38,HHA,-1.00467,0.168804,0.00529129,0.579557 kka2_1:8_L260R,kka2_1:8_260,Kka2,kka2_1:8,P00552,0.579578,NO,260,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.741,-3.961,3.22,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.100394,0.0233782,0.579578 kka2_1:8_L260R,kka2_1:8_260,Kka2,kka2_1:8,P00552,0.579578,NO,260,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.741,-3.961,3.22,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.100394,0.0233782,0.579578 kka2_1:2_C192V,kka2_1:2_192,Kka2,kka2_1:2,P00552,0.579648,NO,192,C,V,CV,Special,Hydrophobic,5.07,5.60847,0.538465,192,121,117,-4,108.5,140,31.5,-1.067,-3.41,2.343,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.295029,0.00485428,0.579648 beta-lactamase_S264W,beta-lactamase_264,TEM-1,beta-lactamase,P62593,0.579652,NO,264,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.985,-5.38,3.395,4.67475,0.04,,B,0.25,0.29,34.251,34.251,73.78,OPP,-2.19867,0.221079,0.0119399,0.579652 kka2_1:1_L53E,kka2_1:1_53,Kka2,kka2_1:1,P00552,0.579662,NO,53,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-2.681,-2.451,-0.23,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.520039,0.00671168,0.579662 beta-lactamase_I140E,beta-lactamase_140,TEM-1,beta-lactamase,P62593,0.579669,NO,140,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.733,-3.925,2.192,5.29918,0.128,H,A,1,0.41,1.16,,73.08,PHO,-1.48733,0.221079,0.00597777,0.579669 kka2_1:1_E161D,kka2_1:1_161,Kka2,kka2_1:1,P00552,0.579688,NO,161,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.581,-2.26,0.679,,0.829,G,A,1.04,2.24,1.612,,92.05,AAB,-1.861,0.520039,0.00760103,0.579688 beta-lactamase_2500_M66T,beta-lactamase_2500_66,TEM-1,beta-lactamase_2500,P62593,0.579697,NO,66,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.362,-3.498,2.136,,0.013,,A,0.55,-0.7,0.502,,73.08,OHH,-1.49567,0.361275,0.00412876,0.579697 beta-lactamase_2500_T126R,beta-lactamase_2500_126,TEM-1,beta-lactamase_2500,P62593,0.579919,NO,126,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.122,-3.84,2.718,,0.05,H,A,0.22,-0.05,0.817,,44.41,HPH,-1.60467,0.361275,0.00244552,0.579919 beta-lactamase_2500_D48Q,beta-lactamase_2500_48,TEM-1,beta-lactamase_2500,P62593,0.579939,NO,48,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.101,-3.681,2.58,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.361275,0.0027273,0.579939 beta-lactamase_2500_S51Y,beta-lactamase_2500_51,TEM-1,beta-lactamase_2500,P62593,0.579961,NO,51,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.526,-4.345,2.819,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.361275,0.00504821,0.579961 beta-lactamase_2500_I140Q,beta-lactamase_2500_140,TEM-1,beta-lactamase_2500,P62593,0.579966,NO,140,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.733,-4.321,2.588,,0.128,H,A,0.48,0.41,1.628,,73.08,PHO,-1.48733,0.361275,0.00597777,0.579966 beta-lactamase_2500_P181A,beta-lactamase_2500_181,TEM-1,beta-lactamase_2500,P62593,0.579974,NO,181,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.813,-2.357,1.544,,,H,A,0.52,-1.14,1.946,,61.54,HOH,-1.795,0.361275,0.000703122,0.579974 kka2_1:2_G99S,kka2_1:2_99,Kka2,kka2_1:2,P00552,0.580012,NO,99,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.596,-3.189,2.593,,0.368,S,g,0.29,-0.87,,,,OOP,-1.63067,0.295029,0.00186055,0.580012 kka2_1:2_A119V,kka2_1:2_119,Kka2,kka2_1:2,P00552,0.580087,NO,119,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.073,-2.406,1.333,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.295029,0.00441074,0.580087 kka2_1:1_D127N,kka2_1:1_127,Kka2,kka2_1:1,P00552,0.580229,NO,127,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.364,-3.671,2.307,,0.573,.,B,0.75,0.45,3.414,,50.38,HAO,-1.51067,0.520039,0.00660501,0.580229 kka2_1:2_E161L,kka2_1:2_161,Kka2,kka2_1:2,P00552,0.58035,NO,161,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.581,-3.558,1.977,,0.829,G,A,1.52,2.24,1.612,,92.05,AAB,-1.861,0.295029,0.00760103,0.58035 PSD95pdz3_G330Q,PSD95pdz3_330,PSD95pdz3,PSD95pdz3,P31016,0.580572,NO,330,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.008,-3.806,2.798,4.68351,,,,,31.405,,,,OOA,-1.14,0.0758425,0.000962386,0.580572 kka2_1:4_I141L,kka2_1:4_141,Kka2,kka2_1:4,P00552,0.580631,NO,141,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.495,-1.454,-0.041,,0.068,H,A,0.48,-0.01,2.144,,92.05,BHA,-1.689,0.168804,0.00744745,0.580631 Ubiquitin_A46D,Ubiquitin_46,Uba1,Ubiquitin,P0CG48,0.580645,NO,46,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.77,-2.42,0.65,5.38761,0.398,T,L,2.34,-0.8,6.506,,51.09,HHO,-1.505,0.205827,0.000581142,0.580645 Ubiquitin_L69W,Ubiquitin_69,Uba1,Ubiquitin,P0CG48,0.580645,NO,69,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.445,-5.238,3.793,4.75624,0.051,E,B,2.89,-0.94,7.106,,34.31,BHH,-1.72933,0.205827,0.000919136,0.580645 Ubiquitin_L73V,Ubiquitin_73,Uba1,Ubiquitin,P0CG48,0.580645,NO,73,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.801,-2.508,0.707,5.27116,0.518,,B,0.77,1,10.519,10.519,34.31,BHB,-1.858,0.205827,0.000710624,0.580645 Ubiquitin_T14K,Ubiquitin_14,Uba1,Ubiquitin,P0CG48,0.580645,NO,14,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.598,-2.513,0.915,5.10811,0.345,E,B,,-0.37,,,,HPH,-1.41133,0.205827,0.000632754,0.580645 Ubiquitin_T66F,Ubiquitin_66,Uba1,Ubiquitin,P0CG48,0.580645,NO,66,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.58,-3.095,1.515,5.02702,0.46,E,B,0.8,-0.81,28.36,28.36,39.71,PPH,-1.51667,0.205827,0.000598414,0.580645 Ubiquitin_V5S,Ubiquitin_5,Uba1,Ubiquitin,P0CG48,0.580645,NO,5,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.576,-3.472,1.896,4.75677,,E,B,,-0.82,,,,HHB,-1.401,0.205827,0.000796998,0.580645 kka2_1:4_G30R,kka2_1:4_30,Kka2,kka2_1:4,P00552,0.580684,NO,30,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.596,-3.961,3.365,,0.54,S,g,0.29,3.76,,,,HOO,-1.51133,0.168804,0.00159208,0.580684 kka2_1:8_C77R,kka2_1:8_77,Kka2,kka2_1:8,P00552,0.580759,NO,77,C,R,CR,Special,PositiveCharge,5.07,6.34148,1.27148,180,121,174,53,108.5,173.4,64.9,-1.477,-4.125,2.648,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.100394,0.00441216,0.580759 kka2_1:8_C77R,kka2_1:8_77,Kka2,kka2_1:8,P00552,0.580759,NO,77,C,R,CR,Special,PositiveCharge,5.07,6.34148,1.27148,180,121,174,53,108.5,173.4,64.9,-1.477,-4.125,2.648,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.100394,0.00441216,0.580759 beta-lactamase_I243A,beta-lactamase_243,TEM-1,beta-lactamase,P62593,0.580825,NO,243,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.532,-3.251,1.719,5.26886,,E,B,1.68,-1.24,2.289,,50,OHH,-1.46867,0.221079,0.00464034,0.580825 beta-lactamase_G43C,beta-lactamase_43,TEM-1,beta-lactamase,P62593,0.580856,NO,43,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.62,-5.087,4.467,5.28886,,E,B,0.77,-0.78,,,,HOH,-1.577,0.221079,0.00120151,0.580856 kka2_1:2_V186L,kka2_1:2_186,Kka2,kka2_1:2,P00552,0.58086,NO,186,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.011,-2.323,1.312,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.295029,0.00409703,0.58086 kka2_1:4_A117R,kka2_1:4_117,Kka2,kka2_1:4,P00552,0.581042,NO,117,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.828,-3.824,2.996,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.168804,0.00282984,0.581042 kka2_1:1_D62L,kka2_1:1_62,Kka2,kka2_1:1,P00552,0.581045,NO,62,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.591,-3.008,1.417,,0.262,H,A,0.75,0.08,10.048,10.048,64.39,PAA,-1.77833,0.520039,0.00744243,0.581045 kka2_1:2_G205S,kka2_1:2_205,Kka2,kka2_1:2,P00552,0.581189,NO,205,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.596,-3.189,2.593,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.295029,0.00221855,0.581189 beta-lactamase_2500_R159I,beta-lactamase_2500_159,TEM-1,beta-lactamase_2500,P62593,0.581208,NO,159,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-0.94,-4.036,3.096,,0.316,,B,1.2,-0.55,2.341,,64.34,PBH,-1.011,0.361275,0.00108472,0.581208 kka2_1:4_R211C,kka2_1:4_211,Kka2,kka2_1:4,P00552,0.581244,NO,211,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-0.899,-5.114,4.215,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.168804,0.00204888,0.581244 beta-lactamase_2500_P65A,beta-lactamase_2500_65,TEM-1,beta-lactamase_2500,P62593,0.581267,NO,65,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.894,-3.096,2.202,,0.098,E,B,0.52,-0.62,0.3,,40.56,HOH,-1.03233,0.361275,0.00152776,0.581267 beta-lactamase_P143M,beta-lactamase_143,TEM-1,beta-lactamase,P62593,0.581373,NO,143,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.967,-4.554,3.587,5.16366,0.075,H,A,0.99,-0.37,0.479,,66.78,OOB,-1.354,0.221079,0.00114551,0.581373 beta-lactamase_39_V31P,beta-lactamase_39_31,TEM-1,beta-lactamase_39,P62593,0.581403,NO,31,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.822,-4.128,2.306,,,H,A,0.44,-0.46,2.885,,73.78,BHB,-2.03767,0.0495842,0.00478065,0.581403 kka2_1:2_L260P,kka2_1:2_260,Kka2,kka2_1:2,P00552,0.581405,NO,260,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.741,-4.133,3.392,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.295029,0.0233782,0.581405 beta-lactamase_2500_E119K,beta-lactamase_2500_119,TEM-1,beta-lactamase_2500,P62593,0.581481,NO,119,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.412,-3.343,1.931,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.361275,0.00386966,0.581481 kka2_1:2_L158A,kka2_1:2_158,Kka2,kka2_1:2,P00552,0.581516,NO,158,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.947,-3.292,1.345,,0.095,,B,1.59,0.77,7.588,,63.64,AHA,-1.25333,0.295029,0.00529068,0.581516 kka2_1:1_E231G,kka2_1:1_231,Kka2,kka2_1:1,P00552,0.581552,NO,231,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.002,-3.247,1.245,,0.503,H,A,1.04,-0.23,25.629,25.629,63.26,AAH,-2.06267,0.520039,0.00732383,0.581552 kka2_1:1_M197C,kka2_1:1_197,Kka2,kka2_1:1,P00552,0.581579,NO,197,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.707,-4.828,3.121,,0.121,E,B,1.59,-1.19,2.097,,65.53,HHH,-1.847,0.520039,0.00921295,0.581579 beta-lactamase_625_G114W,beta-lactamase_625_114,TEM-1,beta-lactamase_625,P62593,0.58165,NO,114,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.094,-5.288,4.194,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.213352,0.00224919,0.58165 PSD95pdz3_I341Y,PSD95pdz3_341,PSD95pdz3,PSD95pdz3,P31016,0.581656,NO,341,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.63,-3.619,1.989,5.73946,,,,,10.3187,,,,HHH,-1.50033,0.0758425,0.000824087,0.581656 beta-lactamase_2500_Y262V,beta-lactamase_2500_262,TEM-1,beta-lactamase_2500,P62593,0.581676,NO,262,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.361275,0.00853516,0.581676 beta-lactamase_2500_L38G,beta-lactamase_2500_38,TEM-1,beta-lactamase_2500,P62593,0.581752,NO,38,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.343,-3.696,2.353,,0.088,H,A,0.55,0.2,2.71,,64.34,PHO,-1.78033,0.361275,0.00373244,0.581752 kka2_1:2_P109K,kka2_1:2_109,Kka2,kka2_1:2,P00552,0.58178,NO,109,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.412,-3.629,2.217,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.295029,0.0070929,0.58178 kka2_1:8_A222E,kka2_1:8_222,Kka2,kka2_1:8,P00552,0.581817,NO,222,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.725,-3.468,2.743,,,H,A,1.04,-1.21,,,,HHH,-1.10833,0.100394,0.00207657,0.581817 kka2_1:8_A222E,kka2_1:8_222,Kka2,kka2_1:8,P00552,0.581817,NO,222,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.725,-3.468,2.743,,,H,A,1.04,-1.21,,,,HHH,-1.10833,0.100394,0.00207657,0.581817 kka2_1:2_E231D,kka2_1:2_231,Kka2,kka2_1:2,P00552,0.581863,NO,231,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.002,-2.09,0.088,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.295029,0.00732383,0.581863 kka2_1:2_G213V,kka2_1:2_213,Kka2,kka2_1:2,P00552,0.581969,NO,213,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.596,-3.782,3.186,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.295029,0.00187654,0.581969 kka2_1:1_Q136T,kka2_1:1_136,Kka2,kka2_1:1,P00552,0.582041,NO,136,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-3.021,-2.627,-0.394,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.520039,0.00624149,0.582041 kka2_1:2_A144E,kka2_1:2_144,Kka2,kka2_1:2,P00552,0.582082,NO,144,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.859,-3.551,2.692,,,H,A,0.46,0.21,6.844,,52.65,BHB,-1.72933,0.295029,0.00231095,0.582082 kka2_1:2_A191G,kka2_1:2_191,Kka2,kka2_1:2,P00552,0.582088,NO,191,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.831,-3.024,2.193,,,.,b,0.46,-0.94,2.046,,50,AHO,-0.868667,0.295029,0.00338807,0.582088 beta-lactamase_0_D174K,beta-lactamase_0_174,TEM-1,beta-lactamase_0,P62593,0.582159,NO,174,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.738,-3.457,2.719,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.0500837,0.00125633,0.582159 kka2_1:1_R18I,kka2_1:1_18,Kka2,kka2_1:1,P00552,0.582231,NO,18,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.055,-3.256,1.201,,0.474,T,A,1.2,0.54,11.422,11.422,71.59,ABH,-1.821,0.520039,0.00724065,0.582231 beta-lactamase_G154W,beta-lactamase_154,TEM-1,beta-lactamase,P62593,0.582275,NO,154,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.823,-5.233,4.41,5.40944,0.54,T,l,0.77,-0.56,2.283,,64.69,HOA,-1.635,0.221079,0.00180205,0.582275 beta-lactamase_2500_G194V,beta-lactamase_2500_194,TEM-1,beta-lactamase_2500,P62593,0.582337,NO,194,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.396,-3.736,2.34,,0.276,S,b,0.29,0.36,3.593,,67.83,POA,-1.832,0.361275,0.00392163,0.582337 beta-lactamase_156_C121Q,beta-lactamase_156_121,TEM-1,beta-lactamase_156,P62593,0.582379,NO,121,C,Q,CQ,Special,Polar,5.07,6.24429,1.17429,154,121,146,25,108.5,143.8,35.3,-0.953,-4.222,3.269,,,H,A,0.46,-0.81,1.136,,63.29,HOP,-1.46767,0.111618,0.000744322,0.582379 kka2_1:2_R66C,kka2_1:2_66,Kka2,kka2_1:2,P00552,0.582395,NO,66,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-0.922,-5.15,4.228,,0.103,H,A,1.2,-0.2,2.659,,46.21,HBH,-1.13567,0.295029,0.00161025,0.582395 kka2_1:1_G205S,kka2_1:1_205,Kka2,kka2_1:1,P00552,0.582495,NO,205,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.596,-3.189,2.593,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.520039,0.00221855,0.582495 kka2_1:2_G30A,kka2_1:2_30,Kka2,kka2_1:2,P00552,0.582618,NO,30,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.596,-2.881,2.285,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.295029,0.00159208,0.582618 beta-lactamase_P224M,beta-lactamase_224,TEM-1,beta-lactamase,P62593,0.582646,NO,224,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.893,-4.704,3.811,5.179,0.383,,B,0.99,-0.3,0.383,,74.48,HOH,-1.26433,0.221079,0.00189564,0.582646 beta-lactamase_Y260T,beta-lactamase_260,TEM-1,beta-lactamase,P62593,0.58269,NO,260,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-1.101,-3.687,2.586,5.50878,,E,B,0.73,-1.04,0.865,,60.49,HHP,-1.83433,0.221079,0.00471757,0.58269 kka2_1:2_R211G,kka2_1:2_211,Kka2,kka2_1:2,P00552,0.58276,NO,211,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-0.899,-3.41,2.511,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.295029,0.00204888,0.58276 beta-lactamase_0_V101W,beta-lactamase_0_101,TEM-1,beta-lactamase_0,P62593,0.582888,NO,101,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.295,-5.385,4.09,,0.342,,B,0.44,0,1.61,,73.08,HHA,-1.54367,0.0500837,0.00374492,0.582888 beta-lactamase_0_D83C,beta-lactamase_0_83,TEM-1,beta-lactamase_0,P62593,0.582945,NO,83,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.066,-5.147,4.081,,0.354,H,A,0.75,0.22,0.617,,48.95,HAH,-1.34733,0.0500837,0.00205968,0.582945 beta-lactamase_0_S128F,beta-lactamase_0_128,TEM-1,beta-lactamase_0,P62593,0.583003,NO,128,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-0.84,-4.067,3.227,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.0500837,0.00071483,0.583003 kka2_1:2_G43P,kka2_1:2_43,Kka2,kka2_1:2,P00552,0.583036,NO,43,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.587,-4.038,2.451,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.295029,0.0071925,0.583036 kka2_1:1_K50Q,kka2_1:1_50,Kka2,kka2_1:1,P00552,0.583085,NO,50,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-0.833,-3.501,2.668,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.520039,0.00138626,0.583085 kka2_1:1_R147L,kka2_1:1_147,Kka2,kka2_1:1,P00552,0.583192,NO,147,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.123,-3.547,2.424,,0.094,H,A,1.2,0.97,2.578,,64.02,PBH,-1.98267,0.520039,0.00549168,0.583192 beta-lactamase_156_S241V,beta-lactamase_156_241,TEM-1,beta-lactamase_156,P62593,0.583429,NO,241,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.111618,0.00452736,0.583429 kka2_1:1_S114E,kka2_1:1_114,Kka2,kka2_1:1,P00552,0.583557,NO,114,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.527,-2.055,-0.472,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.520039,0.00705262,0.583557 kka2_1:1_T187S,kka2_1:1_187,Kka2,kka2_1:1,P00552,0.583634,NO,187,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.273,-2.293,1.02,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.520039,0.00693073,0.583634 WW_domain_P202R,WW_domain_202,Yap65,WW_domain,P46937,0.583694,NO,202,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.4,-3.767,2.367,5.64207,,,,,,17.28,17.28,78.57,AOB,-1.436,0.153962,0.00212903,0.583694 kka2_1:1_G99A,kka2_1:1_99,Kka2,kka2_1:1,P00552,0.583733,NO,99,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.596,-2.881,2.285,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.520039,0.00186055,0.583733 beta-lactamase_2500_P165M,beta-lactamase_2500_165,TEM-1,beta-lactamase_2500,P62593,0.583802,NO,165,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.373,-4.649,3.276,,0.203,T,A,0.52,-0.31,0.414,,73.78,AOA,-1.359,0.361275,0.00549538,0.583802 kka2_1:2_G55W,kka2_1:2_55,Kka2,kka2_1:2,P00552,0.583885,NO,55,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.625,-5.446,3.821,,0.517,S,b,0.75,1.19,15.753,15.753,63.64,POH,-2.05967,0.295029,0.00667877,0.583885 beta-lactamase_A124L,beta-lactamase_124,TEM-1,beta-lactamase,P62593,0.58395,NO,124,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.181,-3.172,1.991,4.58507,,H,A,0.58,-0.9,2.273,,64.34,HHH,-1.152,0.221079,0.00481399,0.58395 kka2_1:1_G210S,kka2_1:1_210,Kka2,kka2_1:1,P00552,0.583979,NO,210,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.095,-1.997,0.902,,0.103,T,A,0.29,-0.62,14.483,14.483,50,OOB,-0.966667,0.520039,0.00598378,0.583979 kka2_1:2_D183G,kka2_1:2_183,Kka2,kka2_1:2,P00552,0.584039,NO,183,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.204,-3.336,2.132,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.295029,0.00426304,0.584039 kka2_1:1_R66H,kka2_1:1_66,Kka2,kka2_1:1,P00552,0.584102,NO,66,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-0.922,-4.322,3.4,,0.103,H,A,1.2,-0.2,2.659,,46.21,HBH,-1.13567,0.520039,0.00161025,0.584102 beta-lactamase_G154V,beta-lactamase_154,TEM-1,beta-lactamase,P62593,0.584115,NO,154,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.823,-3.725,2.902,5.40944,0.54,T,l,0.77,-0.56,2.283,,64.69,HOA,-1.635,0.221079,0.00180205,0.584115 kka2_1:2_G245S,kka2_1:2_245,Kka2,kka2_1:2,P00552,0.584144,NO,245,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.812,-3.212,2.4,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.295029,0.00683899,0.584144 kka2_1:2_Y22H,kka2_1:2_22,Kka2,kka2_1:2,P00552,0.584165,NO,22,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-1.583,-2.746,1.163,,0.122,.,B,0.21,-0.8,1.838,,65.53,OHA,-1.80333,0.295029,0.00598977,0.584165 beta-lactamase_T147Y,beta-lactamase_147,TEM-1,beta-lactamase,P62593,0.584315,NO,147,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.149,-4.243,3.094,5.37474,0.281,H,A,0.8,-0.68,2.838,,64.34,HPH,-1.456,0.221079,0.00226017,0.584315 kka2_1:1_R140G,kka2_1:1_140,Kka2,kka2_1:1,P00552,0.584382,NO,140,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.351,-2.695,1.344,,0.12,H,A,1.2,0.2,11.345,11.345,53.03,BBH,-1.885,0.520039,0.00430167,0.584382 beta-lactamase_625_T131H,beta-lactamase_625_131,TEM-1,beta-lactamase_625,P62593,0.584411,NO,131,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.328,-4.721,3.393,,,H,A,0.22,-0.69,2.031,,67.48,PPH,-1.00867,0.213352,0.00345886,0.584411 beta-lactamase_39_L192D,beta-lactamase_39_192,TEM-1,beta-lactamase_39,P62593,0.584416,NO,192,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.254,-4.104,2.85,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.0495842,0.00558728,0.584416 beta-lactamase_0_I229E,beta-lactamase_0_229,TEM-1,beta-lactamase_0,P62593,0.584456,NO,229,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.267,-3.864,2.597,,0.083,E,B,0.48,-0.76,1.69,,50,HHH,-1.58767,0.0500837,0.00477249,0.584456 kka2_1:1_A168W,kka2_1:1_168,Kka2,kka2_1:1,P00552,0.584477,NO,168,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.989,-5.548,3.559,,0.67,H,A,0.46,0.15,25.546,25.546,64.39,OHA,-2.12933,0.520039,0.00806773,0.584477 WW_domain_P174R,WW_domain_174,Yap65,WW_domain,P46937,0.584522,NO,174,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.035,-3.71,2.675,,,,,,,,,,HOH,-1.261,0.153962,0.000711366,0.584522 beta-lactamase_I93K,beta-lactamase_93,TEM-1,beta-lactamase,P62593,0.584588,NO,93,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.401,-3.873,2.472,5.74695,0.128,E,B,0.77,0.44,1.757,,67.83,BHB,-1.873,0.221079,0.00527066,0.584588 beta-lactamase_625_L284G,beta-lactamase_625_284,TEM-1,beta-lactamase_625,P62593,0.584711,NO,284,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.213352,0.0686156,0.584711 kka2_1:1_L170M,kka2_1:1_170,Kka2,kka2_1:1,P00552,0.58486,NO,170,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.28,-3.089,1.809,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.520039,0.00730791,0.58486 beta-lactamase_2500_G85C,beta-lactamase_2500_85,TEM-1,beta-lactamase_2500,P62593,0.584887,NO,85,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.011,-5.172,4.161,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.361275,0.00252173,0.584887 kka2_1:8_G233T,kka2_1:8_233,Kka2,kka2_1:8,P00552,0.584915,NO,233,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.748,-3.674,2.926,,0.172,,b,0.75,-0.27,1.134,,49.24,HOO,-1.72067,0.100394,0.00232366,0.584915 kka2_1:8_G233T,kka2_1:8_233,Kka2,kka2_1:8,P00552,0.584915,NO,233,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.748,-3.674,2.926,,0.172,,b,0.75,-0.27,1.134,,49.24,HOO,-1.72067,0.100394,0.00232366,0.584915 kka2_1:1_R147C,kka2_1:1_147,Kka2,kka2_1:1,P00552,0.585245,NO,147,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.123,-5.216,4.093,,0.094,H,A,1.2,0.97,2.578,,64.02,PBH,-1.98267,0.520039,0.00549168,0.585245 beta-lactamase_0_E169D,beta-lactamase_0_169,TEM-1,beta-lactamase_0,P62593,0.585269,NO,169,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.23,-3.13,1.9,,0.337,,A,1.04,1,3.516,,73.08,PAH,-1.16533,0.0500837,0.00400994,0.585269 beta-lactamase_2500_W208L,beta-lactamase_2500_208,TEM-1,beta-lactamase_2500,P62593,0.585314,NO,208,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-0.818,-3.358,2.54,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.361275,0.00126609,0.585314 gb1_Q258E,gb1_258,gb1,gb1,P06654,0.585328,NO,258,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.095,-2.906,0.811,,,,,,,0.86,,37.28,BPH,-1.88333,0.177985,0.00437595,0.585328 beta-lactamase_2500_P165Q,beta-lactamase_2500_165,TEM-1,beta-lactamase_2500,P62593,0.585329,NO,165,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.373,-3.97,2.597,,0.203,T,A,0.52,-0.31,0.414,,73.78,AOA,-1.359,0.361275,0.00549538,0.585329 beta-lactamase_156_R257N,beta-lactamase_156_257,TEM-1,beta-lactamase_156,P62593,0.585338,NO,257,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.111618,0.00756629,0.585338 beta-lactamase_T139P,beta-lactamase_139,TEM-1,beta-lactamase,P62593,0.585347,NO,139,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.901,-3.919,2.018,5.69095,0.216,H,A,0.3,0.39,2.256,,77.62,PPH,-2.04667,0.221079,0.00441837,0.585347 beta-lactamase_T27F,beta-lactamase_27,TEM-1,beta-lactamase,P62593,0.585347,NO,27,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.905,-2.968,1.063,5.39752,0.007,H,A,0.69,-0.37,0.745,,93.01,APH,-1.97933,0.221079,0.00306559,0.585347 beta-lactamase_156_E35L,beta-lactamase_156_35,TEM-1,beta-lactamase_156,P62593,0.585375,NO,35,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-0.869,-3.632,2.763,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.111618,0.00174441,0.585375 beta-lactamase_2500_F58T,beta-lactamase_2500_58,TEM-1,beta-lactamase_2500,P62593,0.58542,NO,58,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-2.914,-2.91,-0.004,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.361275,0.00523369,0.58542 Pab1_F149N,Pab1_149,Pab1,Pab1,P04147,0.585423,NO,149,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.149,-3.94,2.791,,0.183,T,A,1.33,1.09,,,,HHO,-1.27767,0.175299,0.000325688,0.585423 WW_domain_L173W,WW_domain_173,Yap65,WW_domain,P46937,0.585474,NO,173,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.117,-4.874,3.757,,,,,,,,,,OHO,-1.06233,0.153962,0.000851849,0.585474 kka2_1:1_C209F,kka2_1:1_209,Kka2,kka2_1:1,P00552,0.585501,NO,209,C,F,CF,Special,Hydrophobic,5.07,3.32051,-1.74949,205,121,165,44,108.5,189.9,81.4,-0.906,-4.063,3.157,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.520039,0.00260862,0.585501 kka2_1:2_R226C,kka2_1:2_226,Kka2,kka2_1:2,P00552,0.585571,NO,226,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.392,-5.171,3.779,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.295029,0.0108032,0.585571 kka2_1:2_I246N,kka2_1:2_246,Kka2,kka2_1:2,P00552,0.585639,NO,246,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-2.008,-4.146,2.138,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.295029,0.0139479,0.585639 beta-lactamase_0_S256F,beta-lactamase_0_256,TEM-1,beta-lactamase_0,P62593,0.585717,NO,256,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.0500837,0.00710634,0.585717 beta-lactamase_156_L205Q,beta-lactamase_156_205,TEM-1,beta-lactamase_156,P62593,0.585721,NO,205,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.922,-4.179,3.257,,,H,A,0.55,-0.46,0.678,,42.31,PHH,-1.57767,0.111618,0.00255802,0.585721 beta-lactamase_G239H,beta-lactamase_239,TEM-1,beta-lactamase,P62593,0.585742,NO,239,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.819,-4.609,3.79,4.85529,0.115,T,l,0.77,-0.62,1.817,,42.31,BOP,-1.45267,0.221079,0.00213852,0.585742 beta-lactamase_625_A211P,beta-lactamase_625_211,TEM-1,beta-lactamase_625,P62593,0.58578,NO,211,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.896,-3.94,2.044,,0.369,T,A,0.46,-0.69,2.061,,77.62,AHA,-1.94633,0.213352,0.00648183,0.58578 beta-lactamase_2500_G226F,beta-lactamase_2500_226,TEM-1,beta-lactamase_2500,P62593,0.585785,NO,226,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.461,-4.428,2.967,,0.701,T,l,0.29,-0.25,5.086,,74.48,HOH,-1.42933,0.361275,0.00665294,0.585785 kka2_1:1_L70R,kka2_1:1_70,Kka2,kka2_1:1,P00552,0.585852,NO,70,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.017,-4.037,3.02,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.520039,0.00411884,0.585852 beta-lactamase_0_I171N,beta-lactamase_0_171,TEM-1,beta-lactamase_0,P62593,0.585923,NO,171,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-2.431,-3.904,1.473,,0.361,,B,0.48,0.53,16.954,16.954,77.62,HHO,-1.55533,0.0500837,0.00623355,0.585923 beta-lactamase_2500_G141E,beta-lactamase_2500_141,TEM-1,beta-lactamase_2500,P62593,0.58599,NO,141,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.828,-2.606,1.778,,0.575,T,l,0.29,-0.28,1.493,,64.69,HOO,-1.08933,0.361275,0.0012419,0.58599 beta-lactamase_0_R176E,beta-lactamase_0_176,TEM-1,beta-lactamase_0,P62593,0.585995,NO,176,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-0.863,-3.215,2.352,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.0500837,0.00105554,0.585995 kka2_1:8_P109F,kka2_1:8_109,Kka2,kka2_1:8,P00552,0.586076,NO,109,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.412,-4.386,2.974,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.100394,0.0070929,0.586076 kka2_1:8_P109F,kka2_1:8_109,Kka2,kka2_1:8,P00552,0.586076,NO,109,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.412,-4.386,2.974,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.100394,0.0070929,0.586076 kka2_1:8_R226T,kka2_1:8_226,Kka2,kka2_1:8,P00552,0.586076,NO,226,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.392,-3.626,2.234,,0.222,H,A,0.16,-0.71,3.818,,56.06,PBA,-1.84767,0.100394,0.0108032,0.586076 kka2_1:8_R226T,kka2_1:8_226,Kka2,kka2_1:8,P00552,0.586076,NO,226,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.392,-3.626,2.234,,0.222,H,A,0.16,-0.71,3.818,,56.06,PBA,-1.84767,0.100394,0.0108032,0.586076 beta-lactamase_2500_S201R,beta-lactamase_2500_201,TEM-1,beta-lactamase_2500,P62593,0.586199,NO,201,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.183,-3.779,2.596,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.361275,0.00198815,0.586199 kka2_1:2_G21I,kka2_1:2_21,Kka2,kka2_1:2,P00552,0.586276,NO,21,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.368,-4.201,2.833,,0.586,T,l,0.29,-0.75,2.026,,71.59,HOH,-2.10167,0.295029,0.00709648,0.586276 beta-lactamase_G114E,beta-lactamase_114,TEM-1,beta-lactamase,P62593,0.58629,NO,114,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.094,-3.605,2.511,4.92659,0.011,,p,0.77,0.35,2.148,,41.61,AOH,-1.43733,0.221079,0.00224919,0.58629 beta-lactamase_39_T107P,beta-lactamase_39_107,TEM-1,beta-lactamase_39,P62593,0.586381,NO,107,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.117,-3.706,2.589,,,G,A,0.22,-0.06,2.686,,67.83,HPA,-1.265,0.0495842,0.00239347,0.586381 beta-lactamase_2500_G52A,beta-lactamase_2500_52,TEM-1,beta-lactamase_2500,P62593,0.586389,NO,52,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.149,-2.316,1.167,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.361275,0.00340138,0.586389 beta-lactamase_L218A,beta-lactamase_218,TEM-1,beta-lactamase,P62593,0.586478,NO,218,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.391,-3.175,1.784,4.88972,,I,b,2.89,-0.53,12.788,12.788,74.48,OHH,-1.58867,0.221079,0.00618274,0.586478 beta-lactamase_A34K,beta-lactamase_34,TEM-1,beta-lactamase,P62593,0.58651,NO,34,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.059,-3.736,1.677,4.9129,,H,A,0.75,-0.54,3.614,,73.78,AHA,-1.74967,0.221079,0.00407913,0.58651 beta-lactamase_2500_P105Y,beta-lactamase_2500_105,TEM-1,beta-lactamase_2500,P62593,0.586592,NO,105,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.813,-4.385,3.572,,0.226,T,A,0.52,0.8,3.1,,63.29,POH,-1.01533,0.361275,0.0011981,0.586592 beta-lactamase_G142K,beta-lactamase_142,TEM-1,beta-lactamase,P62593,0.586743,NO,142,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.707,-3.645,2.938,4.55474,0.034,,p,0.77,-0.64,1.947,,64.69,OOO,-0.834,0.221079,0.00060149,0.586743 beta-lactamase_2500_S201L,beta-lactamase_2500_201,TEM-1,beta-lactamase_2500,P62593,0.586761,NO,201,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.183,-2.615,1.432,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.361275,0.00198815,0.586761 kka2_1:2_T125V,kka2_1:2_125,Kka2,kka2_1:2,P00552,0.586825,NO,125,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.622,-2.85,0.228,,0.791,T,A,0.22,0.33,2.029,,92.05,BPH,-1.56933,0.295029,0.00821755,0.586825 kka2_1:4_K50E,kka2_1:4_50,Kka2,kka2_1:4,P00552,0.586848,NO,50,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-0.833,-3.062,2.229,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.168804,0.00138626,0.586848 beta-lactamase_G114L,beta-lactamase_114,TEM-1,beta-lactamase,P62593,0.586864,NO,114,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.094,-3.637,2.543,4.92659,0.011,,p,0.77,0.35,2.148,,41.61,AOH,-1.43733,0.221079,0.00224919,0.586864 kka2_1:2_S32T,kka2_1:2_32,Kka2,kka2_1:2,P00552,0.586922,NO,32,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-0.804,-3,2.196,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.295029,0.00149998,0.586922 beta-lactamase_0_V42E,beta-lactamase_0_42,TEM-1,beta-lactamase_0,P62593,0.586957,NO,42,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.564,-3.88,2.316,,0.017,E,B,0.44,-0.51,1.659,,63.99,BHO,-1.042,0.0500837,0.00404515,0.586957 kka2_1:2_R143P,kka2_1:2_143,Kka2,kka2_1:2,P00552,0.587022,NO,143,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.525,-4.091,1.566,,0.325,H,A,0.16,1.22,14.853,14.853,65.53,ABH,-1.86833,0.295029,0.00662247,0.587022 kka2_1:2_G201S,kka2_1:2_201,Kka2,kka2_1:2,P00552,0.587106,NO,201,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.56,-2.438,0.878,,0.149,T,l,0.29,-0.57,16.092,16.092,52.65,POB,-1.92233,0.295029,0.00820117,0.587106 kka2_1:2_I207Q,kka2_1:2_207,Kka2,kka2_1:2,P00552,0.587109,NO,207,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.175,-4.367,3.192,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.295029,0.00611824,0.587109 beta-lactamase_I283G,beta-lactamase_283,TEM-1,beta-lactamase,P62593,0.587112,NO,283,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.638,-3.648,2.01,5.4178,0.165,H,A,1.23,0.04,1.576,,69.23,HHB,-1.735,0.221079,0.0429138,0.587112 beta-lactamase_156_N168W,beta-lactamase_156_168,TEM-1,beta-lactamase_156,P62593,0.587151,NO,168,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-1.029,-5.48,4.451,,0.113,G,A,0.61,-0.4,1.014,,44.41,HPA,-1.13233,0.111618,0.00288667,0.587151 kka2_1:1_D62E,kka2_1:1_62,Kka2,kka2_1:1,P00552,0.587195,NO,62,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.591,-2.795,1.204,,0.262,H,A,0.75,0.08,10.048,10.048,64.39,PAA,-1.77833,0.520039,0.00744243,0.587195 beta-lactamase_2500_V214Y,beta-lactamase_2500_214,TEM-1,beta-lactamase_2500,P62593,0.587197,NO,214,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.299,-4.125,2.826,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.361275,0.00628442,0.587197 beta-lactamase_P181G,beta-lactamase_181,TEM-1,beta-lactamase,P62593,0.587225,NO,181,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.813,-3.321,2.508,5.14752,,H,A,1.1,-1.14,1.357,,61.54,HOH,-1.795,0.221079,0.000703122,0.587225 beta-lactamase_P20M,beta-lactamase_20,TEM-1,beta-lactamase,P62593,0.58725,NO,20,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.74,-4.537,2.797,,,,,,,0.368,,67.83,HOH,-1.765,0.221079,0.00235322,0.58725 kka2_1:4_G189R,kka2_1:4_189,Kka2,kka2_1:4,P00552,0.587316,NO,189,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.596,-3.961,3.365,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.168804,0.00253688,0.587316 beta-lactamase_625_L167S,beta-lactamase_625_167,TEM-1,beta-lactamase_625,P62593,0.587322,NO,167,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.138,-2.747,1.609,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.213352,0.00303566,0.587322 beta-lactamase_R220G,beta-lactamase_220,TEM-1,beta-lactamase,P62593,0.587361,NO,220,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-0.942,-3.321,2.379,5.65995,0.295,I,A,0.68,-0.76,2.164,,74.48,HBP,-1.33633,0.221079,0.00232421,0.587361 beta-lactamase_L136T,beta-lactamase_136,TEM-1,beta-lactamase,P62593,0.587367,NO,136,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.232,-3.487,2.255,5.31114,,H,A,2.89,-0.34,1.539,,48.95,HHH,-1.088,0.221079,0.00442304,0.587367 beta-lactamase_N134V,beta-lactamase_134,TEM-1,beta-lactamase,P62593,0.5874,NO,134,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-0.879,-3.751,2.872,5.07245,0.138,H,A,0.09,-0.6,1.441,,53.15,HPH,-1.02233,0.221079,0.000644786,0.5874 kka2_1:8_R226G,kka2_1:8_226,Kka2,kka2_1:8,P00552,0.587464,NO,226,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.392,-2.496,1.104,,0.222,H,A,0.16,-0.71,3.818,,56.06,PBA,-1.84767,0.100394,0.0108032,0.587464 kka2_1:8_R226G,kka2_1:8_226,Kka2,kka2_1:8,P00552,0.587464,NO,226,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.392,-2.496,1.104,,0.222,H,A,0.16,-0.71,3.818,,56.06,PBA,-1.84767,0.100394,0.0108032,0.587464 kka2_1:2_R202I,kka2_1:2_202,Kka2,kka2_1:2,P00552,0.587743,NO,202,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.761,-3.279,1.518,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.295029,0.00696498,0.587743 kka2_1:2_R226H,kka2_1:2_226,Kka2,kka2_1:2,P00552,0.587761,NO,226,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.392,-2.664,1.272,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.295029,0.0108032,0.587761 beta-lactamase_2500_V82M,beta-lactamase_2500_82,TEM-1,beta-lactamase_2500,P62593,0.587828,NO,82,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.325,-4.274,2.949,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.361275,0.00397046,0.587828 beta-lactamase_2500_T27S,beta-lactamase_2500_27,TEM-1,beta-lactamase_2500,P62593,0.58789,NO,27,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.905,-2.606,0.701,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.361275,0.00306559,0.58789 kka2_1:2_S204C,kka2_1:2_204,Kka2,kka2_1:2,P00552,0.588049,NO,204,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.353,-4.762,3.409,,0.144,E,A,0.27,-1.2,2.442,,65.53,HPO,-0.953333,0.295029,0.00881794,0.588049 beta-lactamase_625_D231I,beta-lactamase_625_231,TEM-1,beta-lactamase_625,P62593,0.588076,NO,231,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.816,-4.036,3.22,,,E,B,0.75,-1.06,1.025,,65.38,HAB,-0.994,0.213352,0.00107395,0.588076 kka2_1:8_L174S,kka2_1:8_174,Kka2,kka2_1:8,P00552,0.588098,NO,174,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.952,-3.62,2.668,,,H,A,1.59,-0.31,1.204,,51.89,BHB,-2.08533,0.100394,0.00438501,0.588098 kka2_1:8_L174S,kka2_1:8_174,Kka2,kka2_1:8,P00552,0.588098,NO,174,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.952,-3.62,2.668,,,H,A,1.59,-0.31,1.204,,51.89,BHB,-2.08533,0.100394,0.00438501,0.588098 kka2_1:2_I29A,kka2_1:2_29,Kka2,kka2_1:2,P00552,0.588132,NO,29,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.692,-3.281,1.589,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.295029,0.00619521,0.588132 kka2_1:4_R211S,kka2_1:4_211,Kka2,kka2_1:4,P00552,0.588157,NO,211,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-0.899,-3.475,2.576,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.168804,0.00204888,0.588157 kka2_1:2_T187N,kka2_1:2_187,Kka2,kka2_1:2,P00552,0.588192,NO,187,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.273,-3.75,2.477,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.295029,0.00693073,0.588192 kka2_1:4_D227M,kka2_1:4_227,Kka2,kka2_1:4,P00552,0.588221,NO,227,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.758,-4.662,2.904,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.168804,0.00745029,0.588221 kka2_1:1_D159E,kka2_1:1_159,Kka2,kka2_1:1,P00552,0.588232,NO,159,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.82,-2.917,2.097,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.520039,0.0030485,0.588232 beta-lactamase_0_G76T,beta-lactamase_0_76,TEM-1,beta-lactamase_0,P62593,0.588264,NO,76,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.189,-2.655,1.466,,,H,A,0.29,-0.67,1.188,,67.83,OOH,-1.22267,0.0500837,0.00476637,0.588264 kka2_1:2_L70R,kka2_1:2_70,Kka2,kka2_1:2,P00552,0.588289,NO,70,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.017,-4.037,3.02,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.295029,0.00411884,0.588289 kka2_1:4_R239S,kka2_1:4_239,Kka2,kka2_1:4,P00552,0.588306,NO,239,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.949,-2.753,-0.196,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.168804,0.00835326,0.588306 kka2_1:2_M116K,kka2_1:2_116,Kka2,kka2_1:2,P00552,0.58832,NO,116,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-2.482,-3.871,1.389,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.295029,0.00745147,0.58832 WW_domain_L190T,WW_domain_190,Yap65,WW_domain,P46937,0.588383,NO,190,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.404,-3.404,2,5.53598,,,,,,0.645,,56.55,HHP,-1.51833,0.153962,0.00249186,0.588383 kka2_1:8_L259N,kka2_1:8_259,Kka2,kka2_1:8,P00552,0.588444,NO,259,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.088,-4.082,2.994,,0.036,H,A,1.59,-0.15,1.83,,48.48,BHH,-1.15167,0.100394,0.0206964,0.588444 kka2_1:8_L259N,kka2_1:8_259,Kka2,kka2_1:8,P00552,0.588444,NO,259,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.088,-4.082,2.994,,0.036,H,A,1.59,-0.15,1.83,,48.48,BHH,-1.15167,0.100394,0.0206964,0.588444 kka2_1:1_A87Q,kka2_1:1_87,Kka2,kka2_1:1,P00552,0.588642,NO,87,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.917,-3.008,1.091,,1.039,S,L,0.46,1.57,20.738,20.738,65.53,AHO,-1.822,0.520039,0.00791281,0.588642 Ubiquitin_D58M,Ubiquitin_58,Uba1,Ubiquitin,P0CG48,0.58871,NO,58,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.622,-4.688,3.066,5.06391,0.457,G,A,,-0.54,,,,PAH,-1.60267,0.205827,0.000639847,0.58871 Ubiquitin_E34L,Ubiquitin_34,Uba1,Ubiquitin,P0CG48,0.58871,NO,34,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.294,-3.525,2.231,5.02178,0.406,H,A,1.62,0.6,1.295,,35.62,BAO,-1.24933,0.205827,0.000686048,0.58871 Ubiquitin_G10S,Ubiquitin_10,Uba1,Ubiquitin,P0CG48,0.58871,NO,10,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.396,-2.651,1.255,5.29806,0.115,S,l,,0.2,,,,POB,-1.38633,0.205827,0.000748953,0.58871 Ubiquitin_H68T,Ubiquitin_68,Uba1,Ubiquitin,P0CG48,0.58871,NO,68,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-1.869,-2.889,1.02,4.81902,0.194,E,B,0.72,-1.02,21.325,21.325,65.11,HBH,-1.583,0.205827,0.000925438,0.58871 Ubiquitin_I30R,Ubiquitin_30,Uba1,Ubiquitin,P0CG48,0.58871,NO,30,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.205,-4.095,2.89,4.80264,,H,A,,-0.51,,,,BHP,-1.45133,0.205827,0.000720128,0.58871 Ubiquitin_I61R,Ubiquitin_61,Uba1,Ubiquitin,P0CG48,0.58871,NO,61,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.514,-3.004,1.49,5.19922,0.038,,B,1,-0.76,1.953,,24.53,PHP,-1.70833,0.205827,0.000738268,0.58871 Ubiquitin_T66W,Ubiquitin_66,Uba1,Ubiquitin,P0CG48,0.58871,NO,66,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.58,-5.287,3.707,5.02702,0.46,E,B,0.8,-0.81,28.36,28.36,39.71,PPH,-1.51667,0.205827,0.000598414,0.58871 Ubiquitin_T7L,Ubiquitin_7,Uba1,Ubiquitin,P0CG48,0.58871,NO,7,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.415,-3.044,1.629,4.954,0.094,E,B,0.43,-0.78,0.805,,21.31,BPH,-1.41033,0.205827,0.000647855,0.58871 kka2_1:4_L60G,kka2_1:4_60,Kka2,kka2_1:4,P00552,0.588747,NO,60,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.997,-3.865,2.868,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.168804,0.00262176,0.588747 kka2_1:2_E142P,kka2_1:2_142,Kka2,kka2_1:2,P00552,0.588769,NO,142,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.221,-2.43,0.209,,0.471,H,A,1.52,0.85,3.693,,65.53,HAB,-2.08033,0.295029,0.00748883,0.588769 kka2_1:1_A35G,kka2_1:1_35,Kka2,kka2_1:1,P00552,0.588777,NO,35,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.127,-2.532,0.405,,0.107,E,B,0.46,1.05,8.405,8.405,71.59,HHH,-1.31767,0.520039,0.00630016,0.588777 kka2_1:1_S105I,kka2_1:1_105,Kka2,kka2_1:1,P00552,0.58882,NO,105,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.945,-3.89,1.945,,0.056,S,B,0.27,-1.04,3.442,,65.53,PPB,-2.17033,0.520039,0.00847233,0.58882 kka2_1:2_Q136L,kka2_1:2_136,Kka2,kka2_1:2,P00552,0.588856,NO,136,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-3.021,-3.571,0.55,,0.331,,b,0.4,0.96,2.726,,92.05,BPH,-2.16933,0.295029,0.00624149,0.588856 beta-lactamase_2500_F228L,beta-lactamase_2500_228,TEM-1,beta-lactamase_2500,P62593,0.58914,NO,228,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-2.342,-3.312,0.97,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.361275,0.0046669,0.58914 beta-lactamase_2500_T263H,beta-lactamase_2500_263,TEM-1,beta-lactamase_2500,P62593,0.589175,NO,263,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.361275,0.0110582,0.589175 beta-lactamase_156_V260F,beta-lactamase_156_260,TEM-1,beta-lactamase_156,P62593,0.589221,NO,260,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.111618,0.00471757,0.589221 kka2_1:1_F48V,kka2_1:1_48,Kka2,kka2_1:1,P00552,0.589267,NO,48,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.453,-2.048,0.595,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.520039,0.00475422,0.589267 kka2_1:2_D157Y,kka2_1:2_157,Kka2,kka2_1:2,P00552,0.589313,NO,157,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.993,-4.444,3.451,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.295029,0.0042313,0.589313 kka2_1:1_H162R,kka2_1:1_162,Kka2,kka2_1:1,P00552,0.589354,NO,162,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-2.319,-1.245,-1.074,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.520039,0.00616145,0.589354 kka2_1:4_L243P,kka2_1:4_243,Kka2,kka2_1:4,P00552,0.589398,NO,243,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-2.651,-4.123,1.472,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.168804,0.00884927,0.589398 beta-lactamase_2500_T147A,beta-lactamase_2500_147,TEM-1,beta-lactamase_2500,P62593,0.589474,NO,147,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.149,-2.982,1.833,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.361275,0.00226017,0.589474 beta-lactamase_P143R,beta-lactamase_143,TEM-1,beta-lactamase,P62593,0.5895,NO,143,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.967,-3.999,3.032,5.16366,0.075,H,A,0.99,-0.37,0.479,,66.78,OOB,-1.354,0.221079,0.00114551,0.5895 beta-lactamase_R220H,beta-lactamase_220,TEM-1,beta-lactamase,P62593,0.589558,NO,220,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-0.942,-4.298,3.356,5.65995,0.295,I,A,0.68,-0.76,2.164,,74.48,HBP,-1.33633,0.221079,0.00232421,0.589558 beta-lactamase_2500_S51M,beta-lactamase_2500_51,TEM-1,beta-lactamase_2500,P62593,0.589798,NO,51,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.526,-4.705,3.179,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.361275,0.00504821,0.589798 kka2_1:4_H188R,kka2_1:4_188,Kka2,kka2_1:4,P00552,0.589864,NO,188,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-0.913,-3.509,2.596,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.168804,0.00273139,0.589864 beta-lactamase_0_V42S,beta-lactamase_0_42,TEM-1,beta-lactamase_0,P62593,0.589907,NO,42,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.564,-3.633,2.069,,0.017,E,B,0.44,-0.51,1.659,,63.99,BHO,-1.042,0.0500837,0.00404515,0.589907 kka2_1:1_M178F,kka2_1:1_178,Kka2,kka2_1:1,P00552,0.590014,NO,178,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-3.206,-4.351,1.145,,0.554,.,b,0.55,0.68,3.152,,71.59,BHO,-2.154,0.520039,0.00717253,0.590014 kka2_1:1_E231K,kka2_1:1_231,Kka2,kka2_1:1,P00552,0.5901,NO,231,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.002,-3.423,1.421,,0.503,H,A,1.04,-0.23,25.629,25.629,63.26,AAH,-2.06267,0.520039,0.00732383,0.5901 kka2_1:2_Q27L,kka2_1:2_27,Kka2,kka2_1:2,P00552,0.590128,NO,27,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-1.659,-2.589,0.93,,0.608,.,A,0.64,0.71,0.521,,65.53,PPP,-1.90733,0.295029,0.00595365,0.590128 kka2_1:2_G88E,kka2_1:2_88,Kka2,kka2_1:2,P00552,0.590207,NO,88,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.689,-2.331,0.642,,0.54,S,l,0.75,1.51,2.814,,65.53,HOB,-1.718,0.295029,0.00685559,0.590207 beta-lactamase_625_V117P,beta-lactamase_625_117,TEM-1,beta-lactamase_625,P62593,0.590383,NO,117,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.53,-4.14,2.61,,,H,A,0.44,-0.34,1.23,,65.03,PHB,-1.741,0.213352,0.00467906,0.590383 kka2_1:2_A71W,kka2_1:2_71,Kka2,kka2_1:2,P00552,0.590383,NO,71,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.824,-5.529,3.705,,0.553,H,A,0.46,0.08,9.788,,64.39,HHP,-1.74033,0.295029,0.00727707,0.590383 beta-lactamase_39_P181N,beta-lactamase_39_181,TEM-1,beta-lactamase_39,P62593,0.590424,NO,181,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.813,-3.924,3.111,,,H,A,0.52,-1.14,1.946,,61.54,HOH,-1.795,0.0495842,0.000703122,0.590424 kka2_1:8_A144E,kka2_1:8_144,Kka2,kka2_1:8,P00552,0.590452,NO,144,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.859,-3.551,2.692,,,H,A,1.04,0.21,1.118,,52.65,BHB,-1.72933,0.100394,0.00231095,0.590452 kka2_1:8_A144E,kka2_1:8_144,Kka2,kka2_1:8,P00552,0.590452,NO,144,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.859,-3.551,2.692,,,H,A,1.04,0.21,1.118,,52.65,BHB,-1.72933,0.100394,0.00231095,0.590452 beta-lactamase_2500_I244Y,beta-lactamase_2500_244,TEM-1,beta-lactamase_2500,P62593,0.590503,NO,244,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.555,-4.031,2.476,,,E,B,0.48,-0.84,1.683,,77.62,OHH,-1.385,0.361275,0.00605379,0.590503 beta-lactamase_2500_A247Q,beta-lactamase_2500_247,TEM-1,beta-lactamase_2500,P62593,0.590602,NO,247,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.361275,0.00611275,0.590602 kka2_1:8_R258D,kka2_1:8_258,Kka2,kka2_1:8,P00552,0.590623,NO,258,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.626,-3.765,2.139,,0.316,H,A,0.16,-0.85,5.58,,53.03,HBH,-1.25933,0.100394,0.00983174,0.590623 kka2_1:8_R258D,kka2_1:8_258,Kka2,kka2_1:8,P00552,0.590623,NO,258,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.626,-3.765,2.139,,0.316,H,A,0.16,-0.85,5.58,,53.03,HBH,-1.25933,0.100394,0.00983174,0.590623 PSD95pdz3_L367P,PSD95pdz3_367,PSD95pdz3,PSD95pdz3,P31016,0.59068,NO,367,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.347,-3.786,2.439,5.47696,,,,,17.0063,,,,AHB,-1.39767,0.0758425,0.000466436,0.59068 beta-lactamase_2500_K53C,beta-lactamase_2500_53,TEM-1,beta-lactamase_2500,P62593,0.590761,NO,53,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-2.313,-5.135,2.822,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.361275,0.00383383,0.590761 kka2_1:1_A9T,kka2_1:1_9,Kka2,kka2_1:1,P00552,0.59077,NO,9,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.079,-3.282,1.203,,,,,,,0.383,,71.59,BHO,-2.253,0.520039,0.00273264,0.59077 kka2_1:1_R253C,kka2_1:1_253,Kka2,kka2_1:1,P00552,0.590924,NO,253,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.356,-3.227,1.871,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.520039,0.0144195,0.590924 beta-lactamase_625_C121S,beta-lactamase_625_121,TEM-1,beta-lactamase_625,P62593,0.591002,NO,121,C,S,CS,Special,Polar,5.07,5.68,0.61,112,121,105,-16,108.5,89,-19.5,-0.953,-3.411,2.458,,,H,A,0.46,-0.81,1.143,,63.29,HOP,-1.46767,0.213352,0.000744322,0.591002 beta-lactamase_2500_A148P,beta-lactamase_2500_148,TEM-1,beta-lactamase_2500,P62593,0.591051,NO,148,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.757,-3.925,2.168,,0.379,H,A,0.46,-0.55,2.117,,72.73,PHH,-1.40167,0.361275,0.00547053,0.591051 kka2_1:2_I141L,kka2_1:2_141,Kka2,kka2_1:2,P00552,0.591176,NO,141,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.495,-1.454,-0.041,,0.068,H,A,0.48,-0.01,0.819,,92.05,BHA,-1.689,0.295029,0.00744745,0.591176 beta-lactamase_L218T,beta-lactamase_218,TEM-1,beta-lactamase,P62593,0.591264,NO,218,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.391,-2.536,1.145,4.88972,,I,b,2.89,-0.53,12.788,12.788,74.48,OHH,-1.58867,0.221079,0.00618274,0.591264 beta-lactamase_625_G114M,beta-lactamase_625_114,TEM-1,beta-lactamase_625,P62593,0.591281,NO,114,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.094,-4.83,3.736,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.213352,0.00224919,0.591281 kka2_1:2_A144S,kka2_1:2_144,Kka2,kka2_1:2,P00552,0.591322,NO,144,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.859,-3.103,2.244,,,H,A,0.46,0.21,6.844,,52.65,BHB,-1.72933,0.295029,0.00231095,0.591322 kka2_1:1_L93R,kka2_1:1_93,Kka2,kka2_1:1,P00552,0.591455,NO,93,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.815,-2.776,1.961,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.520039,0.00131498,0.591455 kka2_1:2_K50Q,kka2_1:2_50,Kka2,kka2_1:2,P00552,0.591524,NO,50,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-0.833,-3.501,2.668,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.295029,0.00138626,0.591524 kka2_1:1_L152P,kka2_1:1_152,Kka2,kka2_1:1,P00552,0.591541,NO,152,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.521,-4.119,2.598,,0.547,.,A,0.55,1.36,1.589,,63.64,OHH,-1.162,0.520039,0.00674868,0.591541 beta-lactamase_625_G154P,beta-lactamase_625_154,TEM-1,beta-lactamase_625,P62593,0.591543,NO,154,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.823,-3.881,3.058,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.213352,0.00180205,0.591543 gb1_F256Q,gb1_256,gb1,gb1,P06654,0.591558,NO,256,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.241,-4.126,2.885,,,,,,,,,,HHB,-2.04767,0.177985,0.00435993,0.591558 kka2_1:2_L103C,kka2_1:2_103,Kka2,kka2_1:2,P00552,0.591577,NO,103,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-2.362,-4.794,2.432,,0.394,T,A,0.55,-0.99,3.499,,63.64,HHP,-1.534,0.295029,0.00574792,0.591577 beta-lactamase_2500_P224T,beta-lactamase_2500_224,TEM-1,beta-lactamase_2500,P62593,0.591603,NO,224,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.893,-3.414,2.521,,0.383,,B,0.52,-0.3,2.666,,74.48,HOH,-1.26433,0.361275,0.00189564,0.591603 kka2_1:2_E199G,kka2_1:2_199,Kka2,kka2_1:2,P00552,0.591718,NO,199,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.234,-3.518,1.284,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.295029,0.00854122,0.591718 beta-lactamase_0_S256N,beta-lactamase_0_256,TEM-1,beta-lactamase_0,P62593,0.591805,NO,256,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.0500837,0.00710634,0.591805 beta-lactamase_N134A,beta-lactamase_134,TEM-1,beta-lactamase,P62593,0.591846,NO,134,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-0.879,-3.3,2.421,5.07245,0.138,H,A,0.09,-0.6,1.441,,53.15,HPH,-1.02233,0.221079,0.000644786,0.591846 beta-lactamase_2500_T139F,beta-lactamase_2500_139,TEM-1,beta-lactamase_2500,P62593,0.591872,NO,139,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.901,-4.292,2.391,,0.216,H,A,0.22,0.39,2.256,,77.62,PPH,-2.04667,0.361275,0.00441837,0.591872 beta-lactamase_2500_T116A,beta-lactamase_2500_116,TEM-1,beta-lactamase_2500,P62593,0.591912,NO,116,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.28,-2.469,1.189,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.361275,0.00336175,0.591912 kka2_1:1_A79G,kka2_1:1_79,Kka2,kka2_1:1,P00552,0.591973,NO,79,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.368,-2.844,0.476,,0.563,.,B,0.46,-0.43,7.792,7.792,71.59,HHH,-1.752,0.520039,0.00664821,0.591973 beta-lactamase_0_E119F,beta-lactamase_0_119,TEM-1,beta-lactamase_0,P62593,0.592007,NO,119,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.412,-4.398,2.986,,0.358,H,A,1.04,0.51,3.396,,63.99,BAH,-1.623,0.0500837,0.00386966,0.592007 Pab1_S155R,Pab1_155,Pab1,Pab1,P04147,0.592035,NO,155,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.039,-3.948,1.909,,,,,,,,,,PPB,-1.42267,0.175299,0.00208179,0.592035 beta-lactamase_39_L191D,beta-lactamase_39_191,TEM-1,beta-lactamase_39,P62593,0.59205,NO,191,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.087,-4.092,3.005,,,H,A,0.55,0.09,1.372,,63.29,BHH,-1.445,0.0495842,0.00263549,0.59205 beta-lactamase_P65K,beta-lactamase_65,TEM-1,beta-lactamase,P62593,0.592057,NO,65,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.894,-3.511,2.617,5.59094,0.098,E,B,0.23,-0.62,0.623,,40.56,HOH,-1.03233,0.221079,0.00152776,0.592057 beta-lactamase_D174L,beta-lactamase_174,TEM-1,beta-lactamase,P62593,0.59225,NO,174,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.738,-3.808,3.07,5.44133,0.238,,B,1.22,-0.1,,,,PAA,-1.91233,0.221079,0.00125633,0.59225 beta-lactamase_A235I,beta-lactamase_235,TEM-1,beta-lactamase,P62593,0.592254,NO,235,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.266,-3.683,2.417,4.83024,0.32,E,B,0.52,-0.86,1.344,,50,OHO,-0.89,0.221079,0.00493474,0.592254 kka2_1:1_A255T,kka2_1:1_255,Kka2,kka2_1:1,P00552,0.592343,NO,255,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.715,-3.017,1.302,,0.466,H,A,0.46,-0.52,0.946,,65.53,HHH,-1.71267,0.520039,0.0126809,0.592343 beta-lactamase_0_D48R,beta-lactamase_0_48,TEM-1,beta-lactamase_0,P62593,0.592442,NO,48,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.101,-3.84,2.739,,0.189,E,B,0.75,0.21,17.825,17.825,50.35,HAH,-1.62467,0.0500837,0.0027273,0.592442 beta-lactamase_156_G154I,beta-lactamase_156_154,TEM-1,beta-lactamase_156,P62593,0.592598,NO,154,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.823,-4.173,3.35,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.111618,0.00180205,0.592598 beta-lactamase_625_D212E,beta-lactamase_625_212,TEM-1,beta-lactamase_625,P62593,0.592604,NO,212,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.624,-3.306,1.682,,0.037,,b,0.75,-0.58,1.516,,74.48,HAB,-1.77667,0.213352,0.00644302,0.592604 kka2_1:1_S68I,kka2_1:1_68,Kka2,kka2_1:1,P00552,0.592621,NO,68,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.623,-4.041,1.418,,0.48,H,A,0.27,-0.1,2.655,,71.59,HPH,-1.40767,0.520039,0.00608265,0.592621 beta-lactamase_0_K32W,beta-lactamase_0_32,TEM-1,beta-lactamase_0,P62593,0.592634,NO,32,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.984,-5.48,3.496,,0.563,H,A,2.34,0.34,0.418,,73.08,HBA,-2.04233,0.0500837,0.00401283,0.592634 beta-lactamase_2500_F228K,beta-lactamase_2500_228,TEM-1,beta-lactamase_2500,P62593,0.592656,NO,228,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-2.342,-2.864,0.522,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.361275,0.0046669,0.592656 kka2_1:1_N195S,kka2_1:1_195,Kka2,kka2_1:1,P00552,0.592658,NO,195,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-0.836,-3.008,2.172,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.520039,0.00276134,0.592658 beta-lactamase_G263I,beta-lactamase_263,TEM-1,beta-lactamase,P62593,0.592738,NO,263,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-2.031,-3.163,1.132,5.09799,0.517,S,l,0.77,0.31,16.425,16.425,77.62,POP,-1.78267,0.221079,0.0110582,0.592738 kka2_1:8_D227P,kka2_1:8_227,Kka2,kka2_1:8,P00552,0.592828,NO,227,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.758,-3.728,1.97,,0.128,H,A,0.75,-0.63,0.281,,56.06,BAH,-1.43067,0.100394,0.00745029,0.592828 kka2_1:8_D227P,kka2_1:8_227,Kka2,kka2_1:8,P00552,0.592828,NO,227,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.758,-3.728,1.97,,0.128,H,A,0.75,-0.63,0.281,,56.06,BAH,-1.43067,0.100394,0.00745029,0.592828 kka2_1:2_T28G,kka2_1:2_28,Kka2,kka2_1:2,P00552,0.592956,NO,28,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.883,-2.414,0.531,,0.353,S,B,0.22,2.02,2.655,,63.64,PPH,-1.74467,0.295029,0.00743084,0.592956 beta-lactamase_G142C,beta-lactamase_142,TEM-1,beta-lactamase,P62593,0.593025,NO,142,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.707,-5.05,4.343,4.55474,0.034,,p,0.77,-0.64,1.947,,64.69,OOO,-0.834,0.221079,0.00060149,0.593025 kka2_1:1_A191C,kka2_1:1_191,Kka2,kka2_1:1,P00552,0.593031,NO,191,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.831,-4.548,3.717,,,.,b,0.46,-0.94,0.53,,50,AHO,-0.868667,0.520039,0.00338807,0.593031 beta-lactamase_2500_M153E,beta-lactamase_2500_153,TEM-1,beta-lactamase_2500,P62593,0.593051,NO,153,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-3.193,-3.818,0.625,,0.14,T,A,0.55,-0.11,3.409,,77.62,PHO,-2.25767,0.361275,0.00509109,0.593051 kka2_1:1_V97L,kka2_1:1_97,Kka2,kka2_1:1,P00552,0.59308,NO,97,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.453,-1.404,-0.049,,0.083,,B,1.48,-0.83,13.576,13.576,53.03,AHO,-1.85067,0.520039,0.00737869,0.59308 beta-lactamase_0_S57C,beta-lactamase_0_57,TEM-1,beta-lactamase_0,P62593,0.59324,NO,57,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.918,-4.926,3.008,,0.352,E,B,0.27,-0.18,1.454,,72.73,APH,-2.29167,0.0500837,0.00492804,0.59324 beta-lactamase_2500_F70I,beta-lactamase_2500_70,TEM-1,beta-lactamase_2500,P62593,0.593242,NO,70,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.169,-3.353,2.184,,,H,A,0.58,-1.34,1.918,,63.99,PHB,-0.980667,0.361275,0.00193499,0.593242 kka2_1:4_S105I,kka2_1:4_105,Kka2,kka2_1:4,P00552,0.593243,NO,105,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.945,-3.89,1.945,,0.056,S,B,0.77,-1.04,3.442,,65.53,PPB,-2.17033,0.168804,0.00847233,0.593243 kka2_1:2_A222E,kka2_1:2_222,Kka2,kka2_1:2,P00552,0.593247,NO,222,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.725,-3.468,2.743,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.295029,0.00207657,0.593247 kka2_1:2_R258G,kka2_1:2_258,Kka2,kka2_1:2,P00552,0.593336,NO,258,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.626,-3.635,2.009,,0.316,H,A,1.2,-0.85,7.485,7.485,53.03,HBH,-1.25933,0.295029,0.00983174,0.593336 kka2_1:2_A229H,kka2_1:2_229,Kka2,kka2_1:2,P00552,0.593477,NO,229,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.739,-3.451,1.712,,0.32,H,A,0.46,-0.7,6.549,,63.64,HHA,-1.851,0.295029,0.00942138,0.593477 beta-lactamase_L219K,beta-lactamase_219,TEM-1,beta-lactamase,P62593,0.593552,NO,219,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.313,-3.875,2.562,5.74153,,I,A,0.84,-0.51,2.321,,74.48,HHB,-1.21533,0.221079,0.00664345,0.593552 gb1_G240M,gb1_240,gb1,gb1,P06654,0.593582,NO,240,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.921,-4.665,3.744,,,,,,,,,,BOA,-1.87867,0.177985,0.00270792,0.593582 kka2_1:4_D250M,kka2_1:4_250,Kka2,kka2_1:4,P00552,0.593675,NO,250,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.015,-4.907,3.892,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.168804,0.0177103,0.593675 beta-lactamase_0_D48G,beta-lactamase_0_48,TEM-1,beta-lactamase_0,P62593,0.5937,NO,48,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.101,-3.259,2.158,,0.189,E,B,0.75,0.21,17.825,17.825,50.35,HAH,-1.62467,0.0500837,0.0027273,0.5937 beta-lactamase_625_G39P,beta-lactamase_625_39,TEM-1,beta-lactamase_625,P62593,0.593782,NO,39,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.864,-3.073,1.209,,0.701,T,L,0.29,0.47,29.926,29.926,77.62,HOH,-1.53633,0.213352,0.00487611,0.593782 beta-lactamase_39_A185N,beta-lactamase_39_185,TEM-1,beta-lactamase_39,P62593,0.593841,NO,185,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.406,-4.005,2.599,,,H,A,0.46,-1.02,2.68,,65.03,HHP,-1.84033,0.0495842,0.00467449,0.593841 kka2_1:8_H135R,kka2_1:8_135,Kka2,kka2_1:8,P00552,0.593866,NO,135,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-1.331,-2.597,1.266,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.100394,0.00532566,0.593866 kka2_1:8_H135R,kka2_1:8_135,Kka2,kka2_1:8,P00552,0.593866,NO,135,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-1.331,-2.597,1.266,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.100394,0.00532566,0.593866 beta-lactamase_D231K,beta-lactamase_231,TEM-1,beta-lactamase,P62593,0.593914,NO,231,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.816,-3.42,2.604,5.06651,,E,B,1.22,-1.06,0.319,,65.38,HAB,-0.994,0.221079,0.00107395,0.593914 kka2_1:1_Y244T,kka2_1:1_244,Kka2,kka2_1:1,P00552,0.59407,NO,244,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-0.775,-3.675,2.9,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.520039,0.00453187,0.59407 kka2_1:1_D156T,kka2_1:1_156,Kka2,kka2_1:1,P00552,0.594094,NO,156,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.696,-1.988,0.292,,0.884,T,A,0.75,1.87,1.044,,65.53,PAA,-1.765,0.520039,0.00926998,0.594094 beta-lactamase_0_H151K,beta-lactamase_0_151,TEM-1,beta-lactamase_0,P62593,0.594105,NO,151,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-2.96,-3.032,0.072,,0.594,H,A,0.17,0.1,9.375,,77.62,HBP,-2.34767,0.0500837,0.00216946,0.594105 kka2_1:2_G95V,kka2_1:2_95,Kka2,kka2_1:2,P00552,0.594242,NO,95,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-2.403,-2.997,0.594,,0.126,E,B,0.29,-0.74,0.359,,71.59,HOA,-2.198,0.295029,0.00743616,0.594242 beta-lactamase_A266P,beta-lactamase_266,TEM-1,beta-lactamase,P62593,0.594247,NO,266,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.369,-3.913,2.544,5.02057,0.175,S,B,0.52,0.07,1.832,,64.34,PHP,-2.08567,0.221079,0.0140785,0.594247 kka2_1:8_L223T,kka2_1:8_223,Kka2,kka2_1:8,P00552,0.59426,NO,223,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.861,-3.494,2.633,,,H,A,1.59,-1.24,1.017,,50,HHH,-0.854333,0.100394,0.00253574,0.59426 kka2_1:8_L223T,kka2_1:8_223,Kka2,kka2_1:8,P00552,0.59426,NO,223,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.861,-3.494,2.633,,,H,A,1.59,-1.24,1.017,,50,HHH,-0.854333,0.100394,0.00253574,0.59426 beta-lactamase_2500_V117T,beta-lactamase_2500_117,TEM-1,beta-lactamase_2500,P62593,0.594354,NO,117,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.53,-3.486,1.956,,,H,A,0.44,-0.34,1.23,,65.03,PHB,-1.741,0.361275,0.00467906,0.594354 kka2_1:1_D52I,kka2_1:1_52,Kka2,kka2_1:1,P00552,0.594393,NO,52,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.271,-4.062,1.791,,0.22,E,B,0.75,0.8,2.64,,71.59,PAH,-2.38367,0.520039,0.00175694,0.594393 beta-lactamase_156_R59T,beta-lactamase_156_59,TEM-1,beta-lactamase_156,P62593,0.59442,NO,59,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.345,-3.487,2.142,,0.329,S,L,1.2,-0.09,2.995,,73.08,HBO,-2.24267,0.111618,0.00318082,0.59442 kka2_1:8_T225N,kka2_1:8_225,Kka2,kka2_1:8,P00552,0.594544,NO,225,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.393,-4.009,1.616,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.100394,0.0113598,0.594544 kka2_1:8_T225N,kka2_1:8_225,Kka2,kka2_1:8,P00552,0.594544,NO,225,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.393,-4.009,1.616,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.100394,0.0113598,0.594544 kka2_1:4_I207M,kka2_1:4_207,Kka2,kka2_1:4,P00552,0.594635,NO,207,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.175,-4.117,2.942,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.168804,0.00611824,0.594635 kka2_1:1_A229S,kka2_1:1_229,Kka2,kka2_1:1,P00552,0.594673,NO,229,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.739,-3.404,1.665,,0.32,H,A,0.46,-0.7,6.549,,63.64,HHA,-1.851,0.520039,0.00942138,0.594673 beta-lactamase_625_A246V,beta-lactamase_625_246,TEM-1,beta-lactamase_625,P62593,0.594675,NO,246,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.121,-1.76,-0.361,,0.01,E,B,0.46,-1.01,1.201,,73.78,HHH,-1.55633,0.213352,0.00569458,0.594675 beta-lactamase_T187W,beta-lactamase_187,TEM-1,beta-lactamase,P62593,0.594837,NO,187,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.401,-5.371,3.97,5.11453,0.007,H,A,0.3,-1.19,1.751,,67.48,PPH,-1.69633,0.221079,0.00491782,0.594837 kka2_1:2_D82E,kka2_1:2_82,Kka2,kka2_1:2,P00552,0.594842,NO,82,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.946,-2.436,0.49,,0.341,E,b,0.75,0.52,11.923,11.923,63.64,HAH,-1.98,0.295029,0.00637516,0.594842 beta-lactamase_2500_Q86P,beta-lactamase_2500_86,TEM-1,beta-lactamase_2500,P62593,0.594902,NO,86,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.4,-3.985,1.585,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.361275,0.00450027,0.594902 beta-lactamase_0_T126M,beta-lactamase_0_126,TEM-1,beta-lactamase_0,P62593,0.594964,NO,126,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.122,-4.659,3.537,,0.05,H,A,0.22,-0.05,0.705,,44.41,HPH,-1.60467,0.0500837,0.00244552,0.594964 beta-lactamase_Y103R,beta-lactamase_103,TEM-1,beta-lactamase,P62593,0.595001,NO,103,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-1.33,-3.864,2.534,5.71734,0.613,S,l,2.55,1.21,5.721,,63.29,AHP,-1.48767,0.221079,0.00443048,0.595001 Pab1_G167V,Pab1_167,Pab1,Pab1,P04147,0.595078,NO,167,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.223,-3.505,2.282,,0.195,S,g,,0.03,,,,BOH,-1.25133,0.175299,0.00146449,0.595078 kka2_1:8_K50E,kka2_1:8_50,Kka2,kka2_1:8,P00552,0.595221,NO,50,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-0.833,-3.062,2.229,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.100394,0.00138626,0.595221 kka2_1:8_K50E,kka2_1:8_50,Kka2,kka2_1:8,P00552,0.595221,NO,50,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-0.833,-3.062,2.229,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.100394,0.00138626,0.595221 kka2_1:2_W69Q,kka2_1:2_69,Kka2,kka2_1:2,P00552,0.595226,NO,69,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-0.859,-4.151,3.292,,0.164,H,A,0.47,0.15,5.074,,38.64,PHH,-1.49967,0.295029,0.0012874,0.595226 kka2_1:4_A34R,kka2_1:4_34,Kka2,kka2_1:4,P00552,0.595251,NO,34,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.928,-3.768,2.84,,0.417,.,B,0.46,2.29,0.262,,52.27,AHH,-1.747,0.168804,0.00343484,0.595251 kka2_1:1_T225A,kka2_1:1_225,Kka2,kka2_1:1,P00552,0.595308,NO,225,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.393,-1.787,-0.606,,0.036,H,A,0.22,-1.22,4.554,,63.64,HPB,-1.58733,0.520039,0.0113598,0.595308 kka2_1:4_V186T,kka2_1:4_186,Kka2,kka2_1:4,P00552,0.595313,NO,186,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.011,-3.386,2.375,,,E,B,0.44,-0.61,0.679,,45.83,HHP,-1.10967,0.168804,0.00409703,0.595313 kka2_1:4_R217V,kka2_1:4_217,Kka2,kka2_1:4,P00552,0.595332,NO,217,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.158,-3.458,2.3,,0.252,T,A,1.2,-0.59,2.074,,52.27,ABH,-1.127,0.168804,0.0047191,0.595332 beta-lactamase_2500_C121A,beta-lactamase_2500_121,TEM-1,beta-lactamase_2500,P62593,0.5954,NO,121,C,A,CA,Special,Hydrophobic,5.07,6,0.93,195,121,89,-32,108.5,88.6,-19.9,-0.953,-2.902,1.949,,,H,A,0.46,-0.81,1.174,,63.29,HOP,-1.46767,0.361275,0.000744322,0.5954 beta-lactamase_2500_G141K,beta-lactamase_2500_141,TEM-1,beta-lactamase_2500,P62593,0.595414,NO,141,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.828,-3.62,2.792,,0.575,T,l,0.29,-0.28,1.493,,64.69,HOO,-1.08933,0.361275,0.0012419,0.595414 beta-lactamase_0_T139H,beta-lactamase_0_139,TEM-1,beta-lactamase_0,P62593,0.595461,NO,139,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.901,-3.291,1.39,,0.216,H,A,0.22,0.39,0.421,,77.62,PPH,-2.04667,0.0500837,0.00441837,0.595461 beta-lactamase_2500_R91Q,beta-lactamase_2500_91,TEM-1,beta-lactamase_2500,P62593,0.595466,NO,91,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.392,-2.363,0.971,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.361275,0.00380226,0.595466 kka2_1:8_D208Y,kka2_1:8_208,Kka2,kka2_1:8,P00552,0.59556,NO,208,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.708,-4.416,3.708,,0.36,,l,0.29,-1.01,,,,HAO,-0.929667,0.100394,0.00212588,0.59556 kka2_1:8_D208Y,kka2_1:8_208,Kka2,kka2_1:8,P00552,0.59556,NO,208,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.708,-4.416,3.708,,0.36,,l,0.29,-1.01,,,,HAO,-0.929667,0.100394,0.00212588,0.59556 beta-lactamase_2500_E62G,beta-lactamase_2500_62,TEM-1,beta-lactamase_2500,P62593,0.595676,NO,62,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.193,-2.548,1.355,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.361275,0.00264802,0.595676 Pab1_H172D,Pab1_172,Pab1,Pab1,P04147,0.595684,NO,172,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-1.21,-3.286,2.076,,0.076,E,B,0.35,-0.87,,,,HBH,-1.26667,0.175299,0.000296642,0.595684 kka2_1:1_Q42H,kka2_1:1_42,Kka2,kka2_1:1,P00552,0.595749,NO,42,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.907,-3.3,0.393,,1.044,T,B,0.4,-0.8,2.792,,71.59,HPO,-2.12433,0.520039,0.00679212,0.595749 kka2_1:8_A222D,kka2_1:8_222,Kka2,kka2_1:8,P00552,0.595785,NO,222,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.725,-3.722,2.997,,,H,A,1.04,-1.21,,,,HHH,-1.10833,0.100394,0.00207657,0.595785 kka2_1:8_A222D,kka2_1:8_222,Kka2,kka2_1:8,P00552,0.595785,NO,222,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.725,-3.722,2.997,,,H,A,1.04,-1.21,,,,HHH,-1.10833,0.100394,0.00207657,0.595785 WW_domain_G176D,WW_domain_176,Yap65,WW_domain,P46937,0.595799,NO,176,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.235,-3.451,2.216,6.33142,,,,,,2.71,,78.57,HOH,-1.35467,0.153962,0.00288552,0.595799 hsp90_N588L,hsp90_588,hsp90,hsp90,P02829,0.595849,NO,588,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-3.051,-2.511,0,4.61142,0.019,H,A,0.14,0.39,,,,HPH,-3.12167,0.368192,0.000222939,0.595849 kka2_1:2_R239S,kka2_1:2_239,Kka2,kka2_1:2,P00552,0.595895,NO,239,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.949,-2.753,-0.196,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.295029,0.00835326,0.595895 kka2_1:1_S40A,kka2_1:1_40,Kka2,kka2_1:1,P00552,0.596022,NO,40,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.645,-2.559,-0.086,,0.32,E,B,0.27,-0.9,25.997,25.997,71.59,HPH,-1.91567,0.520039,0.00693477,0.596022 PSD95pdz3_L379N,PSD95pdz3_379,PSD95pdz3,PSD95pdz3,P31016,0.59612,NO,379,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.347,-3.805,2.458,5.37777,,,,,16.8762,,,,HHB,-1.35667,0.0758425,0.00029733,0.59612 beta-lactamase_156_L79E,beta-lactamase_156_79,TEM-1,beta-lactamase_156,P62593,0.596148,NO,79,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.842,-3.887,3.045,,0.007,H,A,0.55,-0.16,1.831,,50.35,HHP,-1.44333,0.111618,0.000947397,0.596148 beta-lactamase_156_I125Q,beta-lactamase_156_125,TEM-1,beta-lactamase_156,P62593,0.596289,NO,125,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.441,-4.226,2.785,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.111618,0.00383964,0.596289 beta-lactamase_0_E35F,beta-lactamase_0_35,TEM-1,beta-lactamase_0,P62593,0.596314,NO,35,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-0.869,-4.318,3.449,,0.15,H,A,1.04,0.21,0.664,,46.85,HAA,-1.88667,0.0500837,0.00174441,0.596314 kka2_1:1_G30R,kka2_1:1_30,Kka2,kka2_1:1,P00552,0.596339,NO,30,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.596,-3.961,3.365,,0.54,S,g,0.29,3.76,,,,HOO,-1.51133,0.520039,0.00159208,0.596339 beta-lactamase_39_L188D,beta-lactamase_39_188,TEM-1,beta-lactamase_39,P62593,0.596342,NO,188,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.166,-3.967,2.801,,,H,A,0.55,-0.3,2.982,,60.14,PHB,-1.47033,0.0495842,0.00295687,0.596342 beta-lactamase_2500_R91C,beta-lactamase_2500_91,TEM-1,beta-lactamase_2500,P62593,0.596424,NO,91,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.392,-5.127,3.735,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.361275,0.00380226,0.596424 beta-lactamase_D212V,beta-lactamase_212,TEM-1,beta-lactamase,P62593,0.596434,NO,212,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.624,-3.608,1.984,4.9705,0.037,,b,1.3,-0.58,12.482,,74.48,HAB,-1.77667,0.221079,0.00644302,0.596434 kka2_1:4_G201V,kka2_1:4_201,Kka2,kka2_1:4,P00552,0.596475,NO,201,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.56,-3.892,2.332,,0.149,T,l,0.29,-0.57,0.284,,52.65,POB,-1.92233,0.168804,0.00820117,0.596475 beta-lactamase_A124N,beta-lactamase_124,TEM-1,beta-lactamase,P62593,0.59669,NO,124,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.181,-3.812,2.631,4.58507,,H,A,0.58,-0.9,2.273,,64.34,HHH,-1.152,0.221079,0.00481399,0.59669 Ubiquitin_E51R,Ubiquitin_51,Uba1,Ubiquitin,P0CG48,0.596774,NO,51,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.534,-3.693,2.159,5.36711,0.545,,B,,0.72,,,,HAA,-1.357,0.205827,0.000868134,0.596774 Ubiquitin_I36H,Ubiquitin_36,Uba1,Ubiquitin,P0CG48,0.596774,NO,36,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.477,-4.771,3.294,5.1035,0.203,,B,0.27,-0.22,1.552,,30.8,OHO,-1.30767,0.205827,0.000630555,0.596774 Ubiquitin_L69A,Ubiquitin_69,Uba1,Ubiquitin,P0CG48,0.596774,NO,69,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.445,-3.194,1.749,4.75624,0.051,E,B,2.89,-0.94,7.106,,34.31,BHH,-1.72933,0.205827,0.000919136,0.596774 Ubiquitin_R42V,Ubiquitin_42,Uba1,Ubiquitin,P0CG48,0.596774,NO,42,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.571,-3.649,2.078,5.07805,0.244,E,B,0.68,-0.54,1.976,,72.85,PBH,-1.38967,0.205827,0.000622265,0.596774 Ubiquitin_R72H,Ubiquitin_72,Uba1,Ubiquitin,P0CG48,0.596774,NO,72,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.034,-4.629,2.595,5.19484,0.077,,B,1.41,-0.1,9.638,9.638,42.77,HBH,-1.82733,0.205827,0.000768249,0.596774 Ubiquitin_T14L,Ubiquitin_14,Uba1,Ubiquitin,P0CG48,0.596774,NO,14,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.598,-3.272,1.674,5.10811,0.345,E,B,,-0.37,,,,HPH,-1.41133,0.205827,0.000632754,0.596774 Ubiquitin_T7Q,Ubiquitin_7,Uba1,Ubiquitin,P0CG48,0.596774,NO,7,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.415,-3.971,2.556,4.954,0.094,E,B,0.43,-0.78,0.805,,21.31,BPH,-1.41033,0.205827,0.000647855,0.596774 Ubiquitin_T7V,Ubiquitin_7,Uba1,Ubiquitin,P0CG48,0.596774,NO,7,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.415,-3.07,1.655,4.954,0.094,E,B,0.43,-0.78,0.805,,21.31,BPH,-1.41033,0.205827,0.000647855,0.596774 kka2_1:8_L212P,kka2_1:8_212,Kka2,kka2_1:8,P00552,0.596796,NO,212,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.904,-4.095,3.191,,,,B,1.59,-0.78,1.708,,42.42,BHO,-0.799667,0.100394,0.0031426,0.596796 kka2_1:8_L212P,kka2_1:8_212,Kka2,kka2_1:8,P00552,0.596796,NO,212,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.904,-4.095,3.191,,,,B,1.59,-0.78,1.708,,42.42,BHO,-0.799667,0.100394,0.0031426,0.596796 beta-lactamase_0_D99W,beta-lactamase_0_99,TEM-1,beta-lactamase_0,P62593,0.596818,NO,99,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.191,-5.462,4.271,,0.402,G,A,0.75,0.36,0.374,,64.69,PAH,-1.794,0.0500837,0.00305446,0.596818 beta-lactamase_S201V,beta-lactamase_201,TEM-1,beta-lactamase,P62593,0.596922,NO,201,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.183,-3.482,2.299,4.85496,0.064,H,A,0.77,-0.07,4.045,,64.69,HPB,-1.451,0.221079,0.00198815,0.596922 beta-lactamase_L120F,beta-lactamase_120,TEM-1,beta-lactamase,P62593,0.596949,NO,120,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.044,-2.785,1.741,5.11974,,H,A,1.3,-1.13,1.988,,64.69,AHO,-1.13633,0.221079,0.00143563,0.596949 kka2_1:2_R211C,kka2_1:2_211,Kka2,kka2_1:2,P00552,0.596963,NO,211,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-0.899,-5.114,4.215,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.295029,0.00204888,0.596963 beta-lactamase_N134C,beta-lactamase_134,TEM-1,beta-lactamase,P62593,0.596981,NO,134,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-0.879,-5.113,4.234,5.07245,0.138,H,A,0.09,-0.6,1.441,,53.15,HPH,-1.02233,0.221079,0.000644786,0.596981 beta-lactamase_P105C,beta-lactamase_105,TEM-1,beta-lactamase,P62593,0.596981,NO,105,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.813,-5.05,4.237,5.08236,0.226,T,A,0.98,0.8,1.154,,63.29,POH,-1.01533,0.221079,0.0011981,0.596981 beta-lactamase_39_I277Q,beta-lactamase_39_277,TEM-1,beta-lactamase_39,P62593,0.597019,NO,277,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.0495842,0.0169305,0.597019 kka2_1:1_D134Q,kka2_1:1_134,Kka2,kka2_1:1,P00552,0.597045,NO,134,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.969,-3.77,2.801,,0.421,B,B,0.75,0.31,2.329,,49.62,HAB,-1.057,0.520039,0.00270812,0.597045 PSD95pdz3_I388W,PSD95pdz3_388,PSD95pdz3,PSD95pdz3,P31016,0.597117,NO,388,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.63,-5.004,3.374,5.17282,,,,,16.0025,,,,PHH,-1.54967,0.0758425,0.000151216,0.597117 beta-lactamase_625_R257C,beta-lactamase_625_257,TEM-1,beta-lactamase_625,P62593,0.597179,NO,257,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.213352,0.00756629,0.597179 kka2_1:4_P167E,kka2_1:4_167,Kka2,kka2_1:4,P00552,0.597247,NO,167,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-2.403,-3.663,1.26,,0.18,H,A,0.52,0.75,3.6,,64.39,HOH,-2.26633,0.168804,0.00543203,0.597247 beta-lactamase_625_R242N,beta-lactamase_625_242,TEM-1,beta-lactamase_625,P62593,0.597252,NO,242,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.213352,0.00452879,0.597252 beta-lactamase_R59G,beta-lactamase_59,TEM-1,beta-lactamase,P62593,0.597282,NO,59,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.345,-3.412,2.067,5.49837,0.329,S,L,0.68,-0.09,1.806,,73.08,HBO,-2.24267,0.221079,0.00318082,0.597282 kka2_1:1_D238N,kka2_1:1_238,Kka2,kka2_1:1,P00552,0.597377,NO,238,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.83,-3.158,0.328,,0.604,H,A,0.75,-0.33,11.329,11.329,92.05,HAB,-2.633,0.520039,0.0113863,0.597377 kka2_1:2_V16P,kka2_1:2_16,Kka2,kka2_1:2,P00552,0.597426,NO,16,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-3.087,-4.081,0.994,,0.742,T,A,0.44,0.34,1.746,,71.59,HHA,-2.211,0.295029,0.00694011,0.597426 beta-lactamase_156_A246I,beta-lactamase_156_246,TEM-1,beta-lactamase_156,P62593,0.59743,NO,246,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.121,-2.179,0.058,,0.01,E,B,0.46,-1.01,1.959,,73.78,HHH,-1.55633,0.111618,0.00569458,0.59743 beta-lactamase_2500_R242S,beta-lactamase_2500_242,TEM-1,beta-lactamase_2500,P62593,0.597539,NO,242,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.361275,0.00452879,0.597539 gb1_A249Q,gb1_249,gb1,gb1,P06654,0.597555,NO,249,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.739,-3.833,2.094,,,,,,,0.252,,44.87,AHH,-1.67367,0.177985,0.00333585,0.597555 gb1_Y229R,gb1_229,gb1,gb1,P06654,0.597555,NO,229,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-1.282,-3.668,2.386,,,,,,,,,,PHB,-1.4915,0.177985,0.00366605,0.597555 beta-lactamase_2500_F149R,beta-lactamase_2500_149,TEM-1,beta-lactamase_2500,P62593,0.597595,NO,149,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.299,-4.139,2.84,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.361275,0.00418462,0.597595 beta-lactamase_2500_N168A,beta-lactamase_2500_168,TEM-1,beta-lactamase_2500,P62593,0.59763,NO,168,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-1.029,-3.17,2.141,,0.113,G,A,0.61,-0.4,2.9,,44.41,HPA,-1.13233,0.361275,0.00288667,0.59763 kka2_1:1_L259C,kka2_1:1_259,Kka2,kka2_1:1,P00552,0.597639,NO,259,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.088,-4.727,3.639,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.520039,0.0206964,0.597639 beta-lactamase_L218F,beta-lactamase_218,TEM-1,beta-lactamase,P62593,0.5977,NO,218,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.391,-2.985,1.594,4.88972,,I,b,2.89,-0.53,12.788,12.788,74.48,OHH,-1.58867,0.221079,0.00618274,0.5977 kka2_1:1_G88S,kka2_1:1_88,Kka2,kka2_1:1,P00552,0.597951,NO,88,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.689,-2.938,1.249,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.520039,0.00685559,0.597951 beta-lactamase_2500_T126K,beta-lactamase_2500_126,TEM-1,beta-lactamase_2500,P62593,0.597982,NO,126,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.122,-3.536,2.414,,0.05,H,A,0.22,-0.05,0.817,,44.41,HPH,-1.60467,0.361275,0.00244552,0.597982 kka2_1:1_P167R,kka2_1:1_167,Kka2,kka2_1:1,P00552,0.598079,NO,167,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-2.403,-4.046,1.643,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.520039,0.00543203,0.598079 beta-lactamase_625_A123N,beta-lactamase_625_123,TEM-1,beta-lactamase_625,P62593,0.598108,NO,123,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.834,-3.947,3.113,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.213352,0.0010157,0.598108 kka2_1:1_V83Q,kka2_1:1_83,Kka2,kka2_1:1,P00552,0.59816,NO,83,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-2.567,-3.072,0.505,,0.358,E,B,0.44,0.53,5.931,,71.59,AHH,-2.264,0.520039,0.00650486,0.59816 beta-lactamase_R241M,beta-lactamase_241,TEM-1,beta-lactamase,P62593,0.598243,NO,241,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.433,-2.871,1.438,5.02621,0.094,E,B,0.68,-0.16,1.327,,50,PBO,-1.42967,0.221079,0.00452736,0.598243 kka2_1:8_L107E,kka2_1:8_107,Kka2,kka2_1:8,P00552,0.598307,NO,107,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.238,-3.847,2.609,,0.197,.,B,0.55,-1.1,4.478,,71.59,BHH,-2.143,0.100394,0.00561937,0.598307 kka2_1:8_L107E,kka2_1:8_107,Kka2,kka2_1:8,P00552,0.598307,NO,107,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.238,-3.847,2.609,,0.197,.,B,0.55,-1.1,4.478,,71.59,BHH,-2.143,0.100394,0.00561937,0.598307 beta-lactamase_2500_F149S,beta-lactamase_2500_149,TEM-1,beta-lactamase_2500,P62593,0.598368,NO,149,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.299,-2.783,1.484,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.361275,0.00418462,0.598368 beta-lactamase_625_D231M,beta-lactamase_625_231,TEM-1,beta-lactamase_625,P62593,0.598407,NO,231,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.816,-4.927,4.111,,,E,B,0.75,-1.06,1.025,,65.38,HAB,-0.994,0.213352,0.00107395,0.598407 kka2_1:8_V185T,kka2_1:8_185,Kka2,kka2_1:8,P00552,0.598419,NO,185,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.045,-3.363,2.318,,0.058,E,B,1.48,-0.49,1.234,,46.97,HHH,-1.184,0.100394,0.00367031,0.598419 kka2_1:8_V185T,kka2_1:8_185,Kka2,kka2_1:8,P00552,0.598419,NO,185,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.045,-3.363,2.318,,0.058,E,B,1.48,-0.49,1.234,,46.97,HHH,-1.184,0.100394,0.00367031,0.598419 beta-lactamase_S104V,beta-lactamase_104,TEM-1,beta-lactamase,P62593,0.598471,NO,104,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.015,-3.487,2.472,4.92365,0.04,,b,0.82,0.57,4.02,,63.29,HPO,-1.05267,0.221079,0.00218083,0.598471 beta-lactamase_0_D48I,beta-lactamase_0_48,TEM-1,beta-lactamase_0,P62593,0.598473,NO,48,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.101,-4.047,2.946,,0.189,E,B,0.75,0.21,17.825,17.825,50.35,HAH,-1.62467,0.0500837,0.0027273,0.598473 kka2_1:1_E3P,kka2_1:1_3,Kka2,kka2_1:1,P00552,0.598571,NO,3,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.199,-3.691,1.492,,,,,,,3.435,,92.05,HAP,-2.11567,0.520039,0.00267607,0.598571 kka2_1:2_L60S,kka2_1:2_60,Kka2,kka2_1:2,P00552,0.598634,NO,60,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.997,-3.713,2.716,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.295029,0.00262176,0.598634 kka2_1:8_H188C,kka2_1:8_188,Kka2,kka2_1:8,P00552,0.598642,NO,188,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-0.913,-5.139,4.226,,0.006,,A,0.87,-1.02,1.241,,47.73,PBO,-0.927333,0.100394,0.00273139,0.598642 kka2_1:8_H188C,kka2_1:8_188,Kka2,kka2_1:8,P00552,0.598642,NO,188,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-0.913,-5.139,4.226,,0.006,,A,0.87,-1.02,1.241,,47.73,PBO,-0.927333,0.100394,0.00273139,0.598642 beta-lactamase_2500_P181C,beta-lactamase_2500_181,TEM-1,beta-lactamase_2500,P62593,0.598677,NO,181,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.813,-5.009,4.196,,,H,A,0.52,-1.14,1.946,,61.54,HOH,-1.795,0.361275,0.000703122,0.598677 beta-lactamase_625_P65N,beta-lactamase_625_65,TEM-1,beta-lactamase_625,P62593,0.598788,NO,65,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.894,-3.952,3.058,,0.098,E,B,0.52,-0.62,0.3,,40.56,HOH,-1.03233,0.213352,0.00152776,0.598788 beta-lactamase_A123E,beta-lactamase_123,TEM-1,beta-lactamase,P62593,0.598843,NO,123,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.834,-3.489,2.655,4.70061,0.039,H,A,0.52,-0.72,0.705,,41.26,PHH,-1.47367,0.221079,0.0010157,0.598843 kka2_1:1_R122G,kka2_1:1_122,Kka2,kka2_1:1,P00552,0.598963,NO,122,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.175,-2.63,0.455,,0.487,H,A,1.2,0.26,1.356,,71.59,BBH,-1.53833,0.520039,0.00736512,0.598963 beta-lactamase_0_M209Y,beta-lactamase_0_209,TEM-1,beta-lactamase_0,P62593,0.599055,NO,209,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.442,-3.865,2.423,,,H,A,0.55,-0.97,3.876,,64.69,HHA,-1.52633,0.0500837,0.00625021,0.599055 PSD95pdz3_I341A,PSD95pdz3_341,PSD95pdz3,PSD95pdz3,P31016,0.599068,NO,341,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.63,-2.759,1.129,5.73946,,,,,10.3187,,,,HHH,-1.50033,0.0758425,0.000824087,0.599068 kka2_1:8_L212S,kka2_1:8_212,Kka2,kka2_1:8,P00552,0.599129,NO,212,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.904,-3.574,2.67,,,,B,1.59,-0.78,1.708,,42.42,BHO,-0.799667,0.100394,0.0031426,0.599129 kka2_1:8_L212S,kka2_1:8_212,Kka2,kka2_1:8,P00552,0.599129,NO,212,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.904,-3.574,2.67,,,,B,1.59,-0.78,1.708,,42.42,BHO,-0.799667,0.100394,0.0031426,0.599129 beta-lactamase_2500_M153K,beta-lactamase_2500_153,TEM-1,beta-lactamase_2500,P62593,0.599181,NO,153,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-3.193,-3.777,0.584,,0.14,T,A,0.55,-0.11,3.409,,77.62,PHO,-2.25767,0.361275,0.00509109,0.599181 kka2_1:2_P45V,kka2_1:2_45,Kka2,kka2_1:2,P00552,0.599184,NO,45,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.774,-3.689,1.915,,0.669,,B,0.52,-0.76,4.882,,71.59,BOH,-2.152,0.295029,0.00590481,0.599184 WW_domain_E178H,WW_domain_178,Yap65,WW_domain,P46937,0.59921,NO,178,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.158,-4.007,2.849,5.22323,,,,,,,,,HAH,-1.299,0.153962,0.0016738,0.59921 beta-lactamase_0_I125Q,beta-lactamase_0_125,TEM-1,beta-lactamase_0,P62593,0.599232,NO,125,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.441,-4.226,2.785,,,H,A,0.48,-0.7,1.874,,63.29,HHP,-1.248,0.0500837,0.00383964,0.599232 beta-lactamase_156_W288D,beta-lactamase_156_288,TEM-1,beta-lactamase_156,P62593,0.59924,NO,288,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,,,,,,,,,,,,,BHO,,0.111618,,0.59924 kka2_1:4_T225S,kka2_1:4_225,Kka2,kka2_1:4,P00552,0.59929,NO,225,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.393,-2.531,0.138,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.168804,0.0113598,0.59929 kka2_1:1_C131F,kka2_1:1_131,Kka2,kka2_1:1,P00552,0.599331,NO,131,C,F,CF,Special,Hydrophobic,5.07,3.32051,-1.74949,205,121,165,44,108.5,189.9,81.4,-0.831,-4.095,3.264,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.520039,0.00170814,0.599331 kka2_1:8_D183I,kka2_1:8_183,Kka2,kka2_1:8,P00552,0.599367,NO,183,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.204,-3.991,2.787,,0.518,.,b,0.75,0.25,0.347,,52.27,AAH,-1.40533,0.100394,0.00426304,0.599367 kka2_1:8_D183I,kka2_1:8_183,Kka2,kka2_1:8,P00552,0.599367,NO,183,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.204,-3.991,2.787,,0.518,.,b,0.75,0.25,0.347,,52.27,AAH,-1.40533,0.100394,0.00426304,0.599367 beta-lactamase_625_H151P,beta-lactamase_625_151,TEM-1,beta-lactamase_625,P62593,0.599398,NO,151,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-2.96,-3.911,0.951,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.213352,0.00216946,0.599398 kka2_1:2_A237E,kka2_1:2_237,Kka2,kka2_1:2,P00552,0.599435,NO,237,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.12,-3.758,1.638,,0.068,H,A,0.46,-0.71,2.369,,92.05,HHA,-2.10433,0.295029,0.012257,0.599435 gb1_A249L,gb1_249,gb1,gb1,P06654,0.599506,NO,249,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.739,-2.977,1.238,,,,,,,0.252,,44.87,AHH,-1.67367,0.177985,0.00333585,0.599506 gb1_L231Y,gb1_231,gb1,gb1,P06654,0.599506,NO,231,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.603,-1.733,0.13,,,,,,,0.219,,11.83,BHH,-1.82633,0.177985,0.00322797,0.599506 beta-lactamase_2500_R91A,beta-lactamase_2500_91,TEM-1,beta-lactamase_2500,P62593,0.599592,NO,91,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.392,-2.55,1.158,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.361275,0.00380226,0.599592 Pab1_F129H,Pab1_129,Pab1,Pab1,P04147,0.599628,NO,129,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.269,-4.114,2.845,,0.219,E,B,0.03,-0.07,1.307,,73.83,HHH,-1.27533,0.175299,0.000625182,0.599628 kka2_1:4_T125P,kka2_1:4_125,Kka2,kka2_1:4,P00552,0.599656,NO,125,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.622,-3.993,1.371,,0.791,T,A,0.82,0.33,1.612,,92.05,BPH,-1.56933,0.168804,0.00821755,0.599656 WW_domain_D201E,WW_domain_201,Yap65,WW_domain,P46937,0.599708,NO,201,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.369,-2.018,0.649,4.90312,,,,,,20.806,20.806,70.04,PAO,-1.456,0.153962,0.00248402,0.599708 beta-lactamase_2500_R91S,beta-lactamase_2500_91,TEM-1,beta-lactamase_2500,P62593,0.599723,NO,91,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.392,-3.342,1.95,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.361275,0.00380226,0.599723 kka2_1:4_S105K,kka2_1:4_105,Kka2,kka2_1:4,P00552,0.599788,NO,105,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.945,-3.628,1.683,,0.056,S,B,0.77,-1.04,3.442,,65.53,PPB,-2.17033,0.168804,0.00847233,0.599788 kka2_1:8_V75K,kka2_1:8_75,Kka2,kka2_1:8,P00552,0.599812,NO,75,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-2.06,-3.819,1.759,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.100394,0.00693733,0.599812 kka2_1:8_V75K,kka2_1:8_75,Kka2,kka2_1:8,P00552,0.599812,NO,75,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-2.06,-3.819,1.759,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.100394,0.00693733,0.599812 kka2_1:8_R217A,kka2_1:8_217,Kka2,kka2_1:8,P00552,0.600094,NO,217,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.158,-3.215,2.057,,0.252,T,A,0.16,-0.59,1.151,,52.27,ABH,-1.127,0.100394,0.0047191,0.600094 kka2_1:8_R217A,kka2_1:8_217,Kka2,kka2_1:8,P00552,0.600094,NO,217,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.158,-3.215,2.057,,0.252,T,A,0.16,-0.59,1.151,,52.27,ABH,-1.127,0.100394,0.0047191,0.600094 kka2_1:8_L47G,kka2_1:8_47,Kka2,kka2_1:8,P00552,0.600145,NO,47,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.265,-3.713,2.448,,0.139,E,B,1.59,-0.86,5.086,,63.26,HHH,-1.77933,0.100394,0.00509386,0.600145 kka2_1:8_L47G,kka2_1:8_47,Kka2,kka2_1:8,P00552,0.600145,NO,47,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.265,-3.713,2.448,,0.139,E,B,1.59,-0.86,5.086,,63.26,HHH,-1.77933,0.100394,0.00509386,0.600145 beta-lactamase_2500_R273H,beta-lactamase_2500_273,TEM-1,beta-lactamase_2500,P62593,0.600285,NO,273,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.314,-4.599,2.285,,0.564,H,A,1.2,1.57,19.943,19.943,73.78,ABP,-1.841,0.361275,0.0077952,0.600285 beta-lactamase_2500_L218I,beta-lactamase_2500_218,TEM-1,beta-lactamase_2500,P62593,0.600293,NO,218,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.391,-3.447,2.056,,,I,b,0.55,-0.53,9.151,9.151,74.48,OHH,-1.58867,0.361275,0.00618274,0.600293 beta-lactamase_39_V260Y,beta-lactamase_39_260,TEM-1,beta-lactamase_39,P62593,0.600311,NO,260,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.101,-3.316,2.215,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.0495842,0.00471757,0.600311 kka2_1:1_A108T,kka2_1:1_108,Kka2,kka2_1:1,P00552,0.600313,NO,108,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.061,-2.374,0.313,,0.243,.,B,0.46,-1.34,3.156,,71.59,HHO,-1.57033,0.520039,0.00751209,0.600313 beta-lactamase_2500_D212S,beta-lactamase_2500_212,TEM-1,beta-lactamase_2500,P62593,0.60033,NO,212,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.624,-2.471,0.847,,0.037,,b,0.75,-0.58,12.482,,74.48,HAB,-1.77667,0.361275,0.00644302,0.60033 beta-lactamase_P224Y,beta-lactamase_224,TEM-1,beta-lactamase,P62593,0.600372,NO,224,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.893,-4.387,3.494,5.179,0.383,,B,0.99,-0.3,0.383,,74.48,HOH,-1.26433,0.221079,0.00189564,0.600372 beta-lactamase_39_E210P,beta-lactamase_39_210,TEM-1,beta-lactamase_39,P62593,0.600383,NO,210,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.319,-4.023,1.704,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.0495842,0.00663582,0.600383 beta-lactamase_156_R257G,beta-lactamase_156_257,TEM-1,beta-lactamase_156,P62593,0.600387,NO,257,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.111618,0.00756629,0.600387 beta-lactamase_156_L160Y,beta-lactamase_156_160,TEM-1,beta-lactamase_156,P62593,0.600429,NO,160,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.977,-3.98,3.003,,0.022,,B,0.55,-0.6,1.095,,44.41,BHA,-0.936,0.111618,0.00193775,0.600429 beta-lactamase_2500_P217I,beta-lactamase_2500_217,TEM-1,beta-lactamase_2500,P62593,0.600434,NO,217,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-2.062,-4.071,2.009,,0.496,I,A,0.52,-0.33,0.431,,74.48,OOH,-1.64333,0.361275,0.00463211,0.600434 beta-lactamase_L282E,beta-lactamase_282,TEM-1,beta-lactamase,P62593,0.600434,NO,282,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.586,-3.901,2.315,5.16743,0.007,H,A,1.07,0.34,31.31,31.31,63.99,PHH,-1.82367,0.221079,0.0449821,0.600434 beta-lactamase_D231P,beta-lactamase_231,TEM-1,beta-lactamase,P62593,0.600472,NO,231,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.816,-3.68,2.864,5.06651,,E,B,1.22,-1.06,0.319,,65.38,HAB,-0.994,0.221079,0.00107395,0.600472 beta-lactamase_39_V31R,beta-lactamase_39_31,TEM-1,beta-lactamase_39,P62593,0.60051,NO,31,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.822,-4.173,2.351,,,H,A,0.44,-0.46,2.885,,73.78,BHB,-2.03767,0.0495842,0.00478065,0.60051 kka2_1:2_C209L,kka2_1:2_209,Kka2,kka2_1:2,P00552,0.600549,NO,209,C,L,CL,Special,Hydrophobic,5.07,9.7088,4.6388,198,121,131,10,108.5,166.7,58.2,-0.906,-2.447,1.541,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.295029,0.00260862,0.600549 kka2_1:2_L102P,kka2_1:2_102,Kka2,kka2_1:2,P00552,0.600561,NO,102,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.804,-4.131,3.327,,,T,A,1.59,-1.17,4.258,,42.42,AHH,-1.398,0.295029,0.00201332,0.600561 kka2_1:8_A119L,kka2_1:8_119,Kka2,kka2_1:8,P00552,0.600578,NO,119,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.073,-3.266,2.193,,0.019,H,A,0.46,-0.57,1.511,,71.59,AHH,-2.34,0.100394,0.00441074,0.600578 kka2_1:8_A119L,kka2_1:8_119,Kka2,kka2_1:8,P00552,0.600578,NO,119,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.073,-3.266,2.193,,0.019,H,A,0.46,-0.57,1.511,,71.59,AHH,-2.34,0.100394,0.00441074,0.600578 kka2_1:1_E160C,kka2_1:1_160,Kka2,kka2_1:1,P00552,0.600849,NO,160,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.683,-5.219,3.536,,0.989,G,A,1.04,2.28,0.273,,71.59,AAA,-1.36133,0.520039,0.00935762,0.600849 kka2_1:4_G205V,kka2_1:4_205,Kka2,kka2_1:4,P00552,0.600961,NO,205,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.596,-3.782,3.186,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.168804,0.00221855,0.600961 beta-lactamase_625_A235I,beta-lactamase_625_235,TEM-1,beta-lactamase_625,P62593,0.600991,NO,235,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.266,-3.683,2.417,,0.32,E,B,0.46,-0.86,0.281,,50,OHO,-0.89,0.213352,0.00493474,0.600991 beta-lactamase_2500_P250V,beta-lactamase_2500_250,TEM-1,beta-lactamase_2500,P62593,0.601035,NO,250,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.361275,0.00550899,0.601035 kka2_1:2_L241Q,kka2_1:2_241,Kka2,kka2_1:2,P00552,0.601083,NO,241,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.158,-4.313,3.155,,0.08,H,A,0.55,-0.82,1.598,,63.26,HHH,-1.58533,0.295029,0.0117299,0.601083 beta-lactamase_2500_H24W,beta-lactamase_2500_24,TEM-1,beta-lactamase_2500,P62593,0.601176,NO,24,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-2.481,-5.305,2.824,,,,,,,0.467,,93.01,OBO,-2.0035,0.361275,0.00238894,0.601176 kka2_1:4_R239N,kka2_1:4_239,Kka2,kka2_1:4,P00552,0.601178,NO,239,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.949,-3.912,0.963,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.168804,0.00835326,0.601178 kka2_1:1_T28N,kka2_1:1_28,Kka2,kka2_1:1,P00552,0.601232,NO,28,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.883,-3.817,1.934,,0.353,S,B,0.22,2.02,1.12,,63.64,PPH,-1.74467,0.520039,0.00743084,0.601232 beta-lactamase_T147W,beta-lactamase_147,TEM-1,beta-lactamase,P62593,0.601239,NO,147,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.149,-5.268,4.119,5.37474,0.281,H,A,0.8,-0.68,2.838,,64.34,HPH,-1.456,0.221079,0.00226017,0.601239 kka2_1:4_F133V,kka2_1:4_133,Kka2,kka2_1:4,P00552,0.60127,NO,133,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-0.871,-3.355,2.484,,0.178,.,B,0.58,0.43,0.786,,42.42,OHA,-0.871667,0.168804,0.00182168,0.60127 beta-lactamase_L219W,beta-lactamase_219,TEM-1,beta-lactamase,P62593,0.601361,NO,219,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.313,-5.183,3.87,5.74153,,I,A,0.84,-0.51,2.321,,74.48,HHB,-1.21533,0.221079,0.00664345,0.601361 beta-lactamase_156_L218R,beta-lactamase_156_218,TEM-1,beta-lactamase_156,P62593,0.601369,NO,218,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.391,-2.276,0.885,,,I,b,0.55,-0.53,17.202,17.202,74.48,OHH,-1.58867,0.111618,0.00618274,0.601369 beta-lactamase_D48I,beta-lactamase_48,TEM-1,beta-lactamase,P62593,0.601392,NO,48,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.101,-4.047,2.946,4.89966,0.189,E,B,0.23,0.21,1.281,,50.35,HAH,-1.62467,0.221079,0.0027273,0.601392 kka2_1:2_D159Q,kka2_1:2_159,Kka2,kka2_1:2,P00552,0.601405,NO,159,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.82,-3.79,2.97,,0.28,.,B,0.75,1.25,0.899,,48.11,HAA,-1.48333,0.295029,0.0030485,0.601405 kka2_1:4_N195S,kka2_1:4_195,Kka2,kka2_1:4,P00552,0.601468,NO,195,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-0.836,-3.008,2.172,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.168804,0.00276134,0.601468 kka2_1:1_T125G,kka2_1:1_125,Kka2,kka2_1:1,P00552,0.601549,NO,125,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.622,-2.508,-0.114,,0.791,T,A,0.22,0.33,1.972,,92.05,BPH,-1.56933,0.520039,0.00821755,0.601549 kka2_1:2_K112R,kka2_1:2_112,Kka2,kka2_1:2,P00552,0.601584,NO,112,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-2.491,-2.2,-0.291,,0.076,H,A,2.34,-1.37,23.433,23.433,56.06,ABH,-2.00133,0.295029,0.00645389,0.601584 kka2_1:1_I141T,kka2_1:1_141,Kka2,kka2_1:1,P00552,0.601658,NO,141,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.495,-3.551,2.056,,0.068,H,A,0.48,-0.01,7.546,7.546,92.05,BHA,-1.689,0.520039,0.00744745,0.601658 kka2_1:2_A224T,kka2_1:2_224,Kka2,kka2_1:2,P00552,0.601721,NO,224,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.977,-1.898,0.921,,,H,A,0.46,-1.26,1.646,,63.64,HHP,-1.41033,0.295029,0.00352047,0.601721 kka2_1:2_K138N,kka2_1:2_138,Kka2,kka2_1:2,P00552,0.60186,NO,138,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-2.5,-3.757,1.257,,0.594,H,A,2.34,0.98,21.038,21.038,71.59,HBB,-2.48833,0.295029,0.00628542,0.60186 kka2_1:2_R89G,kka2_1:2_89,Kka2,kka2_1:2,P00552,0.601927,NO,89,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.548,-2.87,1.322,,0.209,E,B,1.2,1.41,14.396,14.396,64.39,OBA,-1.89867,0.295029,0.00524373,0.601927 kka2_1:2_S40W,kka2_1:2_40,Kka2,kka2_1:2,P00552,0.601968,NO,40,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.645,-5.57,2.925,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.295029,0.00693477,0.601968 beta-lactamase_2500_E62I,beta-lactamase_2500_62,TEM-1,beta-lactamase_2500,P62593,0.602067,NO,62,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.193,-4.086,2.893,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.361275,0.00264802,0.602067 beta-lactamase_N134M,beta-lactamase_134,TEM-1,beta-lactamase,P62593,0.602138,NO,134,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-0.879,-4.702,3.823,5.07245,0.138,H,A,0.09,-0.6,1.441,,53.15,HPH,-1.02233,0.221079,0.000644786,0.602138 beta-lactamase_156_A235D,beta-lactamase_156_235,TEM-1,beta-lactamase_156,P62593,0.602222,NO,235,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.266,-3.668,2.402,,0.32,E,B,0.46,-0.86,1.344,,50,OHO,-0.89,0.111618,0.00493474,0.602222 kka2_1:4_D190L,kka2_1:4_190,Kka2,kka2_1:4,P00552,0.602227,NO,190,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.708,-3.836,3.128,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.168804,0.00247989,0.602227 kka2_1:2_T125Y,kka2_1:2_125,Kka2,kka2_1:2,P00552,0.602293,NO,125,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.622,-4.422,1.8,,0.791,T,A,0.22,0.33,2.029,,92.05,BPH,-1.56933,0.295029,0.00821755,0.602293 beta-lactamase_0_L136C,beta-lactamase_0_136,TEM-1,beta-lactamase_0,P62593,0.602418,NO,136,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.232,-4.751,3.519,,,H,A,0.55,-0.34,0.648,,48.95,HHH,-1.088,0.0500837,0.00442304,0.602418 beta-lactamase_N168E,beta-lactamase_168,TEM-1,beta-lactamase,P62593,0.602423,NO,168,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-1.029,-3.29,2.261,5.42128,0.113,G,A,0.09,-0.4,1.211,,44.41,HPA,-1.13233,0.221079,0.00288667,0.602423 kka2_1:2_M197K,kka2_1:2_197,Kka2,kka2_1:2,P00552,0.602465,NO,197,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.707,-3.81,2.103,,0.121,E,B,0.55,-1.19,2.097,,65.53,HHH,-1.847,0.295029,0.00921295,0.602465 kka2_1:1_Q252R,kka2_1:1_252,Kka2,kka2_1:1,P00552,0.602476,NO,252,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.63,-2.449,-0.181,,0.906,H,A,0.64,0.35,1.369,,92.05,PPB,-2.20733,0.520039,0.0121001,0.602476 beta-lactamase_2500_V259A,beta-lactamase_2500_259,TEM-1,beta-lactamase_2500,P62593,0.60252,NO,259,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.361275,0.0070773,0.60252 beta-lactamase_0_G76K,beta-lactamase_0_76,TEM-1,beta-lactamase_0,P62593,0.602562,NO,76,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.189,-3.631,2.442,,,H,A,0.29,-0.67,1.188,,67.83,OOH,-1.22267,0.0500837,0.00476637,0.602562 beta-lactamase_39_V31D,beta-lactamase_39_31,TEM-1,beta-lactamase_39,P62593,0.602614,NO,31,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.822,-4.049,2.227,,,H,A,0.44,-0.46,2.885,,73.78,BHB,-2.03767,0.0495842,0.00478065,0.602614 kka2_1:4_L232I,kka2_1:4_232,Kka2,kka2_1:4,P00552,0.602625,NO,232,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.514,-2.661,1.147,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.168804,0.00800103,0.602625 kka2_1:4_R258S,kka2_1:4_258,Kka2,kka2_1:4,P00552,0.602625,NO,258,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.626,-3.501,1.875,,0.316,H,A,1.2,-0.85,2.655,,53.03,HBH,-1.25933,0.168804,0.00983174,0.602625 kka2_1:2_L103W,kka2_1:2_103,Kka2,kka2_1:2,P00552,0.602761,NO,103,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-2.362,-5.448,3.086,,0.394,T,A,0.55,-0.99,3.499,,63.64,HHP,-1.534,0.295029,0.00574792,0.602761 kka2_1:1_E230C,kka2_1:1_230,Kka2,kka2_1:1,P00552,0.602765,NO,230,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.672,-3.614,0.942,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.520039,0.00920051,0.602765 beta-lactamase_D161I,beta-lactamase_161,TEM-1,beta-lactamase,P62593,0.602915,NO,161,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.891,-4.034,3.143,5.12208,0.341,,A,0.23,-0.52,1.602,,61.19,HAB,-0.961333,0.221079,0.000897697,0.602915 beta-lactamase_2500_G265L,beta-lactamase_2500_265,TEM-1,beta-lactamase_2500,P62593,0.603043,NO,265,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.361275,0.00811926,0.603043 beta-lactamase_L135H,beta-lactamase_135,TEM-1,beta-lactamase,P62593,0.603098,NO,135,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.002,-4.934,3.932,5.28497,0.117,H,A,1.07,-0.58,0.697,,43.71,PHH,-1.03767,0.221079,0.00244423,0.603098 kka2_1:1_E149D,kka2_1:1_149,Kka2,kka2_1:1,P00552,0.603191,NO,149,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.994,-2.359,0.365,,0.674,H,A,1.04,1.63,3.671,,71.59,HAH,-1.59667,0.520039,0.00803343,0.603191 kka2_1:2_H162C,kka2_1:2_162,Kka2,kka2_1:2,P00552,0.603272,NO,162,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-2.319,-5.188,2.869,,0.071,G,A,0.17,1.01,3.187,,64.39,ABP,-2.02067,0.295029,0.00616145,0.603272 beta-lactamase_I278F,beta-lactamase_278,TEM-1,beta-lactamase,P62593,0.603278,NO,278,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.348,-3.84,2.492,5.35127,0.015,H,A,0.77,-0.85,2.718,,63.29,AHO,-1.41833,0.221079,0.0310297,0.603278 PSD95pdz3_G330N,PSD95pdz3_330,PSD95pdz3,PSD95pdz3,P31016,0.60333,NO,330,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.008,-3.13,2.122,4.68351,,,,,31.405,,,,OOA,-1.14,0.0758425,0.000962386,0.60333 gb1_A249I,gb1_249,gb1,gb1,P06654,0.603337,NO,249,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.739,-3.23,1.491,,,,,,,0.252,,44.87,AHH,-1.67367,0.177985,0.00333585,0.603337 kka2_1:1_G213R,kka2_1:1_213,Kka2,kka2_1:1,P00552,0.603377,NO,213,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.596,-3.961,3.365,,,E,b,0.29,-0.4,,,,HOH,-0.920333,0.520039,0.00187654,0.603377 kka2_1:1_V186Q,kka2_1:1_186,Kka2,kka2_1:1,P00552,0.603425,NO,186,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.011,-4.284,3.273,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.520039,0.00409703,0.603425 kka2_1:1_A229Q,kka2_1:1_229,Kka2,kka2_1:1,P00552,0.603432,NO,229,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.739,-3.175,1.436,,0.32,H,A,0.46,-0.7,6.549,,63.64,HHA,-1.851,0.520039,0.00942138,0.603432 kka2_1:1_G21V,kka2_1:1_21,Kka2,kka2_1:1,P00552,0.603488,NO,21,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.368,-3.817,2.449,,0.586,T,l,0.29,-0.75,10.291,10.291,71.59,HOH,-2.10167,0.520039,0.00709648,0.603488 beta-lactamase_39_F228P,beta-lactamase_39_228,TEM-1,beta-lactamase_39,P62593,0.603592,NO,228,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-2.342,-3.088,0.746,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.0495842,0.0046669,0.603592 kka2_1:1_R66L,kka2_1:1_66,Kka2,kka2_1:1,P00552,0.603623,NO,66,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-0.922,-3.421,2.499,,0.103,H,A,1.2,-0.2,2.659,,46.21,HBH,-1.13567,0.520039,0.00161025,0.603623 kka2_1:1_A237V,kka2_1:1_237,Kka2,kka2_1:1,P00552,0.603641,NO,237,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.12,-1.303,-0.817,,0.068,H,A,0.46,-0.71,2.369,,92.05,HHA,-2.10433,0.520039,0.012257,0.603641 kka2_1:4_Y257D,kka2_1:4_257,Kka2,kka2_1:4,P00552,0.603838,NO,257,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-1.064,-4.006,2.942,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.168804,0.0148191,0.603838 beta-lactamase_2500_L111G,beta-lactamase_2500_111,TEM-1,beta-lactamase_2500,P62593,0.603842,NO,111,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.76,-3.666,1.906,,0.328,T,A,0.55,0.93,1.966,,64.34,BHP,-1.884,0.361275,0.00480671,0.603842 kka2_1:8_W24P,kka2_1:8_24,Kka2,kka2_1:8,P00552,0.603845,NO,24,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-1.779,-4.359,2.58,,0.477,E,B,1.51,-0.21,2.503,,56.06,AHH,-2.24467,0.100394,0.00631564,0.603845 kka2_1:8_W24P,kka2_1:8_24,Kka2,kka2_1:8,P00552,0.603845,NO,24,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-1.779,-4.359,2.58,,0.477,E,B,1.51,-0.21,2.503,,56.06,AHH,-2.24467,0.100394,0.00631564,0.603845 beta-lactamase_R241C,beta-lactamase_241,TEM-1,beta-lactamase,P62593,0.603989,NO,241,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.433,-5.024,3.591,5.02621,0.094,E,B,0.68,-0.16,1.327,,50,PBO,-1.42967,0.221079,0.00452736,0.603989 kka2_1:2_P98M,kka2_1:2_98,Kka2,kka2_1:2,P00552,0.604072,NO,98,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.526,-4.804,3.278,,0.391,S,B,0.52,-0.65,2.82,,63.26,HOO,-1.19167,0.295029,0.00622754,0.604072 beta-lactamase_2500_R63V,beta-lactamase_2500_63,TEM-1,beta-lactamase_2500,P62593,0.604145,NO,63,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-0.943,-3.626,2.683,,0.218,,B,1.2,-0.31,0.929,,44.06,ABH,-0.992333,0.361275,0.00126938,0.604145 beta-lactamase_625_L79F,beta-lactamase_625_79,TEM-1,beta-lactamase_625,P62593,0.604155,NO,79,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.842,-3.643,2.801,,0.007,H,A,0.55,-0.16,0.935,,50.35,HHP,-1.44333,0.213352,0.000947397,0.604155 kka2_1:8_R226C,kka2_1:8_226,Kka2,kka2_1:8,P00552,0.604229,NO,226,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.392,-5.171,3.779,,0.222,H,A,0.16,-0.71,3.818,,56.06,PBA,-1.84767,0.100394,0.0108032,0.604229 kka2_1:8_R226C,kka2_1:8_226,Kka2,kka2_1:8,P00552,0.604229,NO,226,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.392,-5.171,3.779,,0.222,H,A,0.16,-0.71,3.818,,56.06,PBA,-1.84767,0.100394,0.0108032,0.604229 beta-lactamase_0_S128K,beta-lactamase_0_128,TEM-1,beta-lactamase_0,P62593,0.604263,NO,128,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-0.84,-3.232,2.392,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.0500837,0.00071483,0.604263 PSD95pdz3_I341N,PSD95pdz3_341,PSD95pdz3,PSD95pdz3,P31016,0.604302,NO,341,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.63,-3.805,2.175,5.73946,,,,,10.3187,,,,HHH,-1.50033,0.0758425,0.000824087,0.604302 kka2_1:1_V84G,kka2_1:1_84,Kka2,kka2_1:1,P00552,0.60433,NO,84,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-2.279,-3.558,1.279,,0.258,E,B,0.44,1.03,3.484,,71.59,HHP,-2.337,0.520039,0.00724019,0.60433 kka2_1:8_A237Q,kka2_1:8_237,Kka2,kka2_1:8,P00552,0.604338,NO,237,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.12,-4.238,2.118,,0.068,H,A,0.46,-0.71,0.449,,92.05,HHA,-2.10433,0.100394,0.012257,0.604338 kka2_1:8_A237Q,kka2_1:8_237,Kka2,kka2_1:8,P00552,0.604338,NO,237,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.12,-4.238,2.118,,0.068,H,A,0.46,-0.71,0.449,,92.05,HHA,-2.10433,0.100394,0.012257,0.604338 kka2_1:2_A129I,kka2_1:2_129,Kka2,kka2_1:2,P00552,0.604342,NO,129,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.656,-3.236,1.58,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.295029,0.00726862,0.604342 beta-lactamase_0_I229F,beta-lactamase_0_229,TEM-1,beta-lactamase_0,P62593,0.604352,NO,229,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.267,-3.792,2.525,,0.083,E,B,0.48,-0.76,1.69,,50,HHH,-1.58767,0.0500837,0.00477249,0.604352 beta-lactamase_2500_V101H,beta-lactamase_2500_101,TEM-1,beta-lactamase_2500,P62593,0.604383,NO,101,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.295,-4.92,3.625,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.361275,0.00374492,0.604383 beta-lactamase_E46W,beta-lactamase_46,TEM-1,beta-lactamase,P62593,0.604428,NO,46,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.94,-5.418,3.478,5.36461,0.021,E,B,1.51,0.14,0.373,,59.44,HAH,-2.079,0.221079,0.00427568,0.604428 kka2_1:1_H135N,kka2_1:1_135,Kka2,kka2_1:1,P00552,0.60461,NO,135,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-1.331,-3.533,2.202,,0.071,.,a,0.17,0.65,3.574,,53.03,ABP,-1.77367,0.520039,0.00532566,0.60461 beta-lactamase_2500_S51I,beta-lactamase_2500_51,TEM-1,beta-lactamase_2500,P62593,0.604647,NO,51,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.526,-3.925,2.399,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.361275,0.00504821,0.604647 E1_Ubiquitin_L43H,E1_Ubiquitin_43,Uba1,E1_Ubiquitin,P0CG63,0.604775,NO,43,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.188,-4.716,3.528,,,E,B,,-1.17,,,,BHH,-1.30733,0.18783,0.00190185,0.604775 kka2_1:4_M120V,kka2_1:4_120,Kka2,kka2_1:4,P00552,0.604807,NO,120,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-3.877,-2.338,-1.539,,,H,A,0.55,-0.42,2.259,,92.05,HHB,-2.16733,0.168804,0.00265808,0.604807 Ubiquitin_F4H,Ubiquitin_4,Uba1,Ubiquitin,P0CG48,0.604839,NO,4,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.534,-2.859,1.325,4.77459,0.059,E,B,,-0.46,,,,HHH,-1.504,0.205827,0.000805043,0.604839 Ubiquitin_G35P,Ubiquitin_35,Uba1,Ubiquitin,P0CG48,0.604839,NO,35,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.171,-3.924,2.753,4.96213,0.713,,L,,0.2,,,,AOH,-1.314,0.205827,0.000648878,0.604839 Ubiquitin_K6C,Ubiquitin_6,Uba1,Ubiquitin,P0CG48,0.604839,NO,6,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.093,-5.137,4.044,4.84211,0.35,E,B,1.82,-0.62,1.502,,71.82,HBP,-1.36133,0.205827,0.000784795,0.604839 Ubiquitin_V17E,Ubiquitin_17,Uba1,Ubiquitin,P0CG48,0.604839,NO,17,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.314,-3.758,2.444,5.26282,0.017,,B,2.78,-0.77,3.239,,71.82,AHA,-1.51833,0.205827,0.000659638,0.604839 Ubiquitin_V70T,Ubiquitin_70,Uba1,Ubiquitin,P0CG48,0.604839,NO,70,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.874,-2.642,0.768,5.29728,0.05,E,B,0.96,-0.97,2.363,,34.31,HHH,-1.65533,0.205827,0.00106871,0.604839 beta-lactamase_625_C75L,beta-lactamase_625_75,TEM-1,beta-lactamase_625,P62593,0.604878,NO,75,C,L,CL,Special,Hydrophobic,5.07,9.7088,4.6388,198,121,131,10,108.5,166.7,58.2,-1.245,-3.28,2.035,,,H,A,0.46,-0.87,2.141,,50,HOO,-1.24333,0.213352,0.0034616,0.604878 beta-lactamase_625_I244T,beta-lactamase_625_244,TEM-1,beta-lactamase_625,P62593,0.605053,NO,244,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.555,-2.572,1.017,,,E,B,0.48,-0.84,2.061,,77.62,OHH,-1.385,0.213352,0.00605379,0.605053 beta-lactamase_L188W,beta-lactamase_188,TEM-1,beta-lactamase,P62593,0.605068,NO,188,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.166,-3.108,1.942,5.55434,,H,A,1.07,-0.3,1.574,,60.14,PHB,-1.47033,0.221079,0.00295687,0.605068 beta-lactamase_39_G243E,beta-lactamase_39_243,TEM-1,beta-lactamase_39,P62593,0.605205,NO,243,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.0495842,0.00464034,0.605205 gb1_G240P,gb1_240,gb1,gb1,P06654,0.605219,NO,240,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.921,-3.615,2.694,,,,,,,,,,BOA,-1.87867,0.177985,0.00270792,0.605219 kka2_1:4_F203C,kka2_1:4_203,Kka2,kka2_1:4,P00552,0.605298,NO,203,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-0.911,-4.889,3.978,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.168804,0.00318738,0.605298 kka2_1:4_A144S,kka2_1:4_144,Kka2,kka2_1:4,P00552,0.605325,NO,144,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.859,-3.103,2.244,,,H,A,0.46,0.21,6.844,,52.65,BHB,-1.72933,0.168804,0.00231095,0.605325 kka2_1:4_L103D,kka2_1:4_103,Kka2,kka2_1:4,P00552,0.605327,NO,103,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-2.362,-3.76,1.398,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.168804,0.00574792,0.605327 beta-lactamase_625_S68I,beta-lactamase_625_68,TEM-1,beta-lactamase_625,P62593,0.605345,NO,68,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-0.913,-3.834,2.921,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.213352,0.000800065,0.605345 beta-lactamase_156_L120Y,beta-lactamase_156_120,TEM-1,beta-lactamase_156,P62593,0.605357,NO,120,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.044,-3.856,2.812,,,H,A,0.55,-1.13,7.813,,64.69,AHO,-1.13633,0.111618,0.00143563,0.605357 beta-lactamase_T261W,beta-lactamase_261,TEM-1,beta-lactamase,P62593,0.605514,NO,261,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.88,-5.264,2.384,5.65483,0.014,E,B,0.53,-0.39,2.449,,77.62,HPP,-1.771,0.221079,0.0123091,0.605514 beta-lactamase_625_P250W,beta-lactamase_625_250,TEM-1,beta-lactamase_625,P62593,0.605519,NO,250,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.213352,0.00550899,0.605519 kka2_1:2_T51K,kka2_1:2_51,Kka2,kka2_1:2,P00552,0.605519,NO,51,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.199,-3.076,0.877,,0.05,E,B,0.22,-0.05,13.165,13.165,63.64,BPA,-1.76767,0.295029,0.00628861,0.605519 beta-lactamase_2500_V214N,beta-lactamase_2500_214,TEM-1,beta-lactamase_2500,P62593,0.605745,NO,214,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.299,-3.962,2.663,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.361275,0.00628442,0.605745 beta-lactamase_0_E35V,beta-lactamase_0_35,TEM-1,beta-lactamase_0,P62593,0.605866,NO,35,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-0.869,-3.578,2.709,,0.15,H,A,1.04,0.21,0.664,,46.85,HAA,-1.88667,0.0500837,0.00174441,0.605866 beta-lactamase_R241A,beta-lactamase_241,TEM-1,beta-lactamase,P62593,0.605872,NO,241,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.433,-2.581,1.148,5.02621,0.094,E,B,0.68,-0.16,1.327,,50,PBO,-1.42967,0.221079,0.00452736,0.605872 kka2_1:1_H139F,kka2_1:1_139,Kka2,kka2_1:1,P00552,0.605917,NO,139,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-2.809,-3.506,0.697,,0.471,H,A,0.17,0.68,1.153,,63.64,BBB,-2.22,0.520039,0.00734779,0.605917 beta-lactamase_2500_R202H,beta-lactamase_2500_202,TEM-1,beta-lactamase_2500,P62593,0.605924,NO,202,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.292,-4.365,3.073,,0.188,H,A,1.2,0.62,3.734,,77.62,PBP,-1.54767,0.361275,0.00321899,0.605924 beta-lactamase_625_L137G,beta-lactamase_625_137,TEM-1,beta-lactamase_625,P62593,0.606008,NO,137,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.03,-3.837,2.807,,,H,A,0.55,-0.38,1.5,,42.31,HHP,-1.58933,0.213352,0.00278599,0.606008 beta-lactamase_2500_V82Y,beta-lactamase_2500_82,TEM-1,beta-lactamase_2500,P62593,0.606043,NO,82,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.325,-4.133,2.808,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.361275,0.00397046,0.606043 kka2_1:1_Q155S,kka2_1:1_155,Kka2,kka2_1:1,P00552,0.606096,NO,155,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.606,-3.295,0.689,,0.525,T,A,0.4,1.49,4.415,,63.64,APA,-1.726,0.520039,0.00641853,0.606096 kka2_1:4_H135G,kka2_1:4_135,Kka2,kka2_1:4,P00552,0.606123,NO,135,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-1.331,-3.471,2.14,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.168804,0.00532566,0.606123 kka2_1:4_P132G,kka2_1:4_132,Kka2,kka2_1:4,P00552,0.60628,NO,132,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.775,-3.354,2.579,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.168804,0.0018489,0.60628 kka2_1:8_L107R,kka2_1:8_107,Kka2,kka2_1:8,P00552,0.606361,NO,107,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.238,-4.11,2.872,,0.197,.,B,0.55,-1.1,4.478,,71.59,BHH,-2.143,0.100394,0.00561937,0.606361 kka2_1:8_L107R,kka2_1:8_107,Kka2,kka2_1:8,P00552,0.606361,NO,107,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.238,-4.11,2.872,,0.197,.,B,0.55,-1.1,4.478,,71.59,BHH,-2.143,0.100394,0.00561937,0.606361 beta-lactamase_A215V,beta-lactamase_215,TEM-1,beta-lactamase,P62593,0.606423,NO,215,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.503,-3.464,1.961,4.82164,,,a,0.75,-0.93,3.583,,74.48,HHO,-1.42633,0.221079,0.00544007,0.606423 beta-lactamase_0_L47F,beta-lactamase_0_47,TEM-1,beta-lactamase_0,P62593,0.606429,NO,47,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.876,-3.101,1.225,,0.007,E,B,0.55,0.2,1.024,,67.83,AHA,-1.639,0.0500837,0.00439844,0.606429 kka2_1:4_F240Q,kka2_1:4_240,Kka2,kka2_1:4,P00552,0.606435,NO,240,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-0.911,-4.376,3.465,,,H,A,0.58,-1.21,5.798,,50.38,BHH,-1.67267,0.168804,0.00552543,0.606435 kka2_1:8_D220Y,kka2_1:8_220,Kka2,kka2_1:8,P00552,0.606524,NO,220,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.787,-4.383,3.596,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.100394,0.00158066,0.606524 kka2_1:8_D220Y,kka2_1:8_220,Kka2,kka2_1:8,P00552,0.606524,NO,220,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.787,-4.383,3.596,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.100394,0.00158066,0.606524 kka2_1:4_W236A,kka2_1:4_236,Kka2,kka2_1:4,P00552,0.606605,NO,236,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-1.363,-2.534,1.171,,0.303,H,A,0.47,-0.76,2.277,,48.48,AHH,-1.81267,0.168804,0.0088796,0.606605 beta-lactamase_0_G76M,beta-lactamase_0_76,TEM-1,beta-lactamase_0,P62593,0.606641,NO,76,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.189,-4.767,3.578,,,H,A,0.29,-0.67,1.188,,67.83,OOH,-1.22267,0.0500837,0.00476637,0.606641 kka2_1:2_A137E,kka2_1:2_137,Kka2,kka2_1:2,P00552,0.606736,NO,137,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.156,-3.863,1.707,,0.029,H,A,0.46,0.34,1.323,,63.26,PHB,-2.559,0.295029,0.00515054,0.606736 kka2_1:2_G205C,kka2_1:2_205,Kka2,kka2_1:2,P00552,0.606752,NO,205,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.596,-5.115,4.519,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.295029,0.00221855,0.606752 kka2_1:4_D159Y,kka2_1:4_159,Kka2,kka2_1:4,P00552,0.606757,NO,159,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.82,-4.45,3.63,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.168804,0.0030485,0.606757 kka2_1:8_F263L,kka2_1:8_263,Kka2,kka2_1:8,P00552,0.606851,NO,263,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-0.911,-2.161,1.25,,0.006,G,A,1.62,-0.12,0.928,,45.83,AHH,-0.92,0.100394,0.0172454,0.606851 kka2_1:8_F263L,kka2_1:8_263,Kka2,kka2_1:8,P00552,0.606851,NO,263,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-0.911,-2.161,1.25,,0.006,G,A,1.62,-0.12,0.928,,45.83,AHH,-0.92,0.100394,0.0172454,0.606851 kka2_1:4_K175Y,kka2_1:4_175,Kka2,kka2_1:4,P00552,0.606865,NO,175,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-2.897,-3.379,0.482,,0.579,H,A,1.3,0.51,15.629,15.629,71.59,HBH,-1.82333,0.168804,0.00693093,0.606865 kka2_1:4_P167S,kka2_1:4_167,Kka2,kka2_1:4,P00552,0.606865,NO,167,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-2.403,-2.618,0.215,,0.18,H,A,0.52,0.75,3.6,,64.39,HOH,-2.26633,0.168804,0.00543203,0.606865 kka2_1:1_L53I,kka2_1:1_53,Kka2,kka2_1:1,P00552,0.606878,NO,53,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-2.681,-2.859,0.178,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.520039,0.00671168,0.606878 kka2_1:1_F264S,kka2_1:1_264,Kka2,kka2_1:1,P00552,0.606915,NO,264,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.02,-3.713,2.693,,0.296,.,?,0.58,0.02,2.303,,71.59,HHNA,-0.9655,0.520039,,0.606915 beta-lactamase_2500_T126D,beta-lactamase_2500_126,TEM-1,beta-lactamase_2500,P62593,0.606982,NO,126,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.122,-2.344,1.222,,0.05,H,A,0.22,-0.05,0.817,,44.41,HPH,-1.60467,0.361275,0.00244552,0.606982 beta-lactamase_D48Y,beta-lactamase_48,TEM-1,beta-lactamase,P62593,0.607111,NO,48,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.101,-4.182,3.081,4.89966,0.189,E,B,0.23,0.21,1.281,,50.35,HAH,-1.62467,0.221079,0.0027273,0.607111 kka2_1:1_G164H,kka2_1:1_164,Kka2,kka2_1:1,P00552,0.607144,NO,164,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.869,-4.642,3.773,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.520039,0.00442091,0.607144 kka2_1:4_M148S,kka2_1:4_148,Kka2,kka2_1:4,P00552,0.607222,NO,148,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.847,-3.618,1.771,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.168804,0.00982664,0.607222 kka2_1:4_M148W,kka2_1:4_148,Kka2,kka2_1:4,P00552,0.607264,NO,148,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.847,-5.364,3.517,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.168804,0.00982664,0.607264 kka2_1:1_E262G,kka2_1:1_262,Kka2,kka2_1:1,P00552,0.607342,NO,262,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-0.829,-3.41,2.581,,0.059,G,A,1.04,-0.18,0.837,,42.42,AAH,-0.816,0.520039,0.0191586,0.607342 kka2_1:4_G30S,kka2_1:4_30,Kka2,kka2_1:4,P00552,0.607436,NO,30,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.596,-3.189,2.593,,0.54,S,g,0.29,3.76,,,,HOO,-1.51133,0.168804,0.00159208,0.607436 beta-lactamase_625_T263K,beta-lactamase_625_263,TEM-1,beta-lactamase_625,P62593,0.607443,NO,263,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.213352,0.0110582,0.607443 Pab1_G188P,Pab1_188,Pab1,Pab1,P04147,0.607607,NO,188,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.809,-3.697,2.888,,0.379,E,g,,2.18,,,,POH,-1.14633,0.175299,0.000280911,0.607607 beta-lactamase_G114T,beta-lactamase_114,TEM-1,beta-lactamase,P62593,0.607685,NO,114,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.094,-2.276,1.182,4.92659,0.011,,p,0.77,0.35,2.148,,41.61,AOH,-1.43733,0.221079,0.00224919,0.607685 kka2_1:4_R143E,kka2_1:4_143,Kka2,kka2_1:4,P00552,0.607936,NO,143,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.525,-2.41,-0.115,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.168804,0.00662247,0.607936 kka2_1:8_A78E,kka2_1:8_78,Kka2,kka2_1:8,P00552,0.607937,NO,78,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.744,-3.513,1.769,,0.078,,B,1.04,-0.53,1.251,,56.06,OHH,-1.863,0.100394,0.00457299,0.607937 kka2_1:8_A78E,kka2_1:8_78,Kka2,kka2_1:8,P00552,0.607937,NO,78,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.744,-3.513,1.769,,0.078,,B,1.04,-0.53,1.251,,56.06,OHH,-1.863,0.100394,0.00457299,0.607937 beta-lactamase_2500_T139Y,beta-lactamase_2500_139,TEM-1,beta-lactamase_2500,P62593,0.608004,NO,139,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.901,-4.252,2.351,,0.216,H,A,0.22,0.39,2.256,,77.62,PPH,-2.04667,0.361275,0.00441837,0.608004 beta-lactamase_L160G,beta-lactamase_160,TEM-1,beta-lactamase,P62593,0.608021,NO,160,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.977,-3.824,2.847,5.32068,0.022,,B,1.75,-0.6,0.895,,44.41,BHA,-0.936,0.221079,0.00193775,0.608021 beta-lactamase_2500_V214Q,beta-lactamase_2500_214,TEM-1,beta-lactamase_2500,P62593,0.608033,NO,214,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.299,-4.141,2.842,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.361275,0.00628442,0.608033 beta-lactamase_0_V106W,beta-lactamase_0_106,TEM-1,beta-lactamase_0,P62593,0.60808,NO,106,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.218,-5.22,4.002,,0.258,T,A,0.44,0.24,0.952,,72.73,OHP,-1.04933,0.0500837,0.00304168,0.60808 beta-lactamase_R63G,beta-lactamase_63,TEM-1,beta-lactamase,P62593,0.608119,NO,63,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-0.943,-3.426,2.483,5.49979,0.218,,B,0.45,-0.31,0.677,,44.06,ABH,-0.992333,0.221079,0.00126938,0.608119 kka2_1:2_D208G,kka2_1:2_208,Kka2,kka2_1:2,P00552,0.608171,NO,208,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.708,-3.161,2.453,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.295029,0.00212588,0.608171 beta-lactamase_156_W227H,beta-lactamase_156_227,TEM-1,beta-lactamase_156,P62593,0.608216,NO,227,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-0.982,-4.704,3.722,,0.272,,B,0.47,-0.29,2.533,,74.48,OHH,-1.595,0.111618,0.00226019,0.608216 beta-lactamase_0_S128C,beta-lactamase_0_128,TEM-1,beta-lactamase_0,P62593,0.608224,NO,128,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-0.84,-4.637,3.797,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.0500837,0.00071483,0.608224 kka2_1:2_G181L,kka2_1:2_181,Kka2,kka2_1:2,P00552,0.608284,NO,181,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-2.698,-3.595,0.897,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.295029,0.00728319,0.608284 E1_Ubiquitin_I44G,E1_Ubiquitin_44,Uba1,E1_Ubiquitin,P0CG63,0.608311,NO,44,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.432,-3.572,2.14,,,E,B,0.27,-1.17,4.57,,78.74,HHH,-1.25633,0.18783,0.00209731,0.608311 E1_Ubiquitin_R72M,E1_Ubiquitin_72,Uba1,E1_Ubiquitin,P0CG63,0.608311,NO,72,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.184,-4.297,3.113,,0.077,,B,0.16,-0.1,,,,HBH,-1.08733,0.18783,0.00129853,0.608311 beta-lactamase_0_L47G,beta-lactamase_0_47,TEM-1,beta-lactamase_0,P62593,0.608316,NO,47,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.876,-3.777,1.901,,0.007,E,B,0.55,0.2,1.024,,67.83,AHA,-1.639,0.0500837,0.00439844,0.608316 kka2_1:8_I207Q,kka2_1:8_207,Kka2,kka2_1:8,P00552,0.608479,NO,207,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.175,-4.367,3.192,,0.293,,B,1.52,-1.12,1.306,,56.06,HHA,-1.07733,0.100394,0.00611824,0.608479 kka2_1:8_I207Q,kka2_1:8_207,Kka2,kka2_1:8,P00552,0.608479,NO,207,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.175,-4.367,3.192,,0.293,,B,1.52,-1.12,1.306,,56.06,HHA,-1.07733,0.100394,0.00611824,0.608479 beta-lactamase_G52C,beta-lactamase_52,TEM-1,beta-lactamase,P62593,0.608507,NO,52,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.149,-5.084,3.935,5.12093,0.299,,l,0.77,-0.04,2.103,,64.69,POB,-1.66267,0.221079,0.00340138,0.608507 kka2_1:2_E161F,kka2_1:2_161,Kka2,kka2_1:2,P00552,0.608554,NO,161,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.581,-4.379,2.798,,0.829,G,A,1.52,2.24,1.612,,92.05,AAB,-1.861,0.295029,0.00760103,0.608554 beta-lactamase_39_L136F,beta-lactamase_39_136,TEM-1,beta-lactamase_39,P62593,0.608556,NO,136,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.232,-3.77,2.538,,,H,A,0.55,-0.34,0.336,,48.95,HHH,-1.088,0.0495842,0.00442304,0.608556 beta-lactamase_625_L192H,beta-lactamase_625_192,TEM-1,beta-lactamase_625,P62593,0.608572,NO,192,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.254,-4.926,3.672,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.213352,0.00558728,0.608572 kka2_1:1_L241Q,kka2_1:1_241,Kka2,kka2_1:1,P00552,0.608749,NO,241,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.158,-4.313,3.155,,0.08,H,A,0.55,-0.82,1.685,,63.26,HHH,-1.58533,0.520039,0.0117299,0.608749 kka2_1:2_E161T,kka2_1:2_161,Kka2,kka2_1:2,P00552,0.608791,NO,161,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.581,-2.315,0.734,,0.829,G,A,1.52,2.24,1.612,,92.05,AAB,-1.861,0.295029,0.00760103,0.608791 kka2_1:1_H106E,kka2_1:1_106,Kka2,kka2_1:1,P00552,0.608846,NO,106,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-3.13,-2.347,-0.783,,1.065,.,a,0.17,-0.95,2.53,,71.59,PBH,-2.10433,0.520039,0.00730778,0.608846 beta-lactamase_39_S233F,beta-lactamase_39_233,TEM-1,beta-lactamase_39,P62593,0.608885,NO,233,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.886,-4.226,2.34,,0.016,E,B,0.27,-1.01,5.361,,77.62,BPO,-1.17267,0.0495842,0.00311415,0.608885 PSD95pdz3_L367E,PSD95pdz3_367,PSD95pdz3,PSD95pdz3,P31016,0.608951,NO,367,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.347,-3.572,2.225,5.47696,,,,,17.0063,,,,AHB,-1.39767,0.0758425,0.000466436,0.608951 kka2_1:2_R217G,kka2_1:2_217,Kka2,kka2_1:2,P00552,0.608988,NO,217,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.158,-3.574,2.416,,0.252,T,A,1.2,-0.59,0.381,,52.27,ABH,-1.127,0.295029,0.0047191,0.608988 kka2_1:1_A119S,kka2_1:1_119,Kka2,kka2_1:1,P00552,0.609062,NO,119,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.073,-2.181,1.108,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.520039,0.00441074,0.609062 kka2_1:2_P249F,kka2_1:2_249,Kka2,kka2_1:2,P00552,0.6091,NO,249,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.867,-3.04,1.173,,0.406,.,B,0.52,-0.01,0.76,,92.05,HOA,-1.66867,0.295029,0.011045,0.6091 beta-lactamase_I140G,beta-lactamase_140,TEM-1,beta-lactamase,P62593,0.609201,NO,140,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.733,-3.828,2.095,5.29918,0.128,H,A,1,0.41,1.16,,73.08,PHO,-1.48733,0.221079,0.00597777,0.609201 beta-lactamase_L137N,beta-lactamase_137,TEM-1,beta-lactamase,P62593,0.609262,NO,137,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.03,-4.152,3.122,5.20117,,H,A,1.07,-0.38,0.674,,42.31,HHP,-1.58933,0.221079,0.00278599,0.609262 kka2_1:8_P45W,kka2_1:8_45,Kka2,kka2_1:8,P00552,0.60929,NO,45,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.774,-5.588,3.814,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.100394,0.00590481,0.60929 kka2_1:8_P45W,kka2_1:8_45,Kka2,kka2_1:8,P00552,0.60929,NO,45,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.774,-5.588,3.814,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.100394,0.00590481,0.60929 beta-lactamase_D231Y,beta-lactamase_231,TEM-1,beta-lactamase,P62593,0.609341,NO,231,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.816,-4.385,3.569,5.06651,,E,B,1.22,-1.06,0.319,,65.38,HAB,-0.994,0.221079,0.00107395,0.609341 kka2_1:1_R145S,kka2_1:1_145,Kka2,kka2_1:1,P00552,0.609347,NO,145,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.804,-2.769,0.965,,0.346,H,A,1.2,1.23,23.699,23.699,63.64,HBP,-1.88033,0.520039,0.00846663,0.609347 kka2_1:8_L184G,kka2_1:8_184,Kka2,kka2_1:8,P00552,0.609398,NO,184,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.496,-3.006,1.51,,0.489,E,B,0.55,-0.06,4.495,,63.26,AHH,-1.24833,0.100394,0.00518742,0.609398 kka2_1:8_L184G,kka2_1:8_184,Kka2,kka2_1:8,P00552,0.609398,NO,184,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.496,-3.006,1.51,,0.489,E,B,0.55,-0.06,4.495,,63.26,AHH,-1.24833,0.100394,0.00518742,0.609398 kka2_1:8_I141K,kka2_1:8_141,Kka2,kka2_1:8,P00552,0.609452,NO,141,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.495,-3.912,2.417,,0.068,H,A,1.52,-0.01,2.144,,92.05,BHA,-1.689,0.100394,0.00744745,0.609452 kka2_1:8_I141K,kka2_1:8_141,Kka2,kka2_1:8,P00552,0.609452,NO,141,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.495,-3.912,2.417,,0.068,H,A,1.52,-0.01,2.144,,92.05,BHA,-1.689,0.100394,0.00744745,0.609452 kka2_1:2_P167G,kka2_1:2_167,Kka2,kka2_1:2,P00552,0.609727,NO,167,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-2.403,-3.388,0.985,,0.18,H,A,0.52,0.75,3.6,,64.39,HOH,-2.26633,0.295029,0.00543203,0.609727 beta-lactamase_39_D155F,beta-lactamase_39_155,TEM-1,beta-lactamase_39,P62593,0.609748,NO,155,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.889,-4.341,3.452,,0.049,,B,0.75,-0.9,3.208,,64.69,OAB,-1.62267,0.0495842,0.00135315,0.609748 kka2_1:2_I141F,kka2_1:2_141,Kka2,kka2_1:2,P00552,0.609811,NO,141,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.495,-3.83,2.335,,0.068,H,A,0.48,-0.01,0.819,,92.05,BHA,-1.689,0.295029,0.00744745,0.609811 Pab1_H172G,Pab1_172,Pab1,Pab1,P04147,0.609838,NO,172,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-1.21,-3.175,1.965,,0.076,E,B,0.35,-0.87,,,,HBH,-1.26667,0.175299,0.000296642,0.609838 beta-lactamase_L218G,beta-lactamase_218,TEM-1,beta-lactamase,P62593,0.609864,NO,218,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.391,-3.644,2.253,4.88972,,I,b,2.89,-0.53,12.788,12.788,74.48,OHH,-1.58867,0.221079,0.00618274,0.609864 beta-lactamase_2500_F149K,beta-lactamase_2500_149,TEM-1,beta-lactamase_2500,P62593,0.609868,NO,149,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.299,-3.859,2.56,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.361275,0.00418462,0.609868 beta-lactamase_D83H,beta-lactamase_83,TEM-1,beta-lactamase,P62593,0.609923,NO,83,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.066,-4.503,3.437,5.40616,0.354,H,A,1.33,0.22,0.861,,48.95,HAH,-1.34733,0.221079,0.00205968,0.609923 beta-lactamase_2500_F149E,beta-lactamase_2500_149,TEM-1,beta-lactamase_2500,P62593,0.609927,NO,149,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.299,-3.842,2.543,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.361275,0.00418462,0.609927 kka2_1:4_E96T,kka2_1:4_96,Kka2,kka2_1:4,P00552,0.610067,NO,96,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.573,-2.511,-0.062,,0.476,,B,1.52,-0.65,1.254,,71.59,OAH,-2.143,0.168804,0.00369441,0.610067 kka2_1:4_L152P,kka2_1:4_152,Kka2,kka2_1:4,P00552,0.61024,NO,152,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.521,-4.119,2.598,,0.547,,A,1.59,1.36,2.318,,63.64,OHH,-1.162,0.168804,0.00674868,0.61024 beta-lactamase_156_V31G,beta-lactamase_156_31,TEM-1,beta-lactamase_156,P62593,0.610244,NO,31,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.822,-3.699,1.877,,,H,A,0.44,-0.46,4.126,,73.78,BHB,-2.03767,0.111618,0.00478065,0.610244 beta-lactamase_156_S104I,beta-lactamase_156_104,TEM-1,beta-lactamase_156,P62593,0.610318,NO,104,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.015,-3.786,2.771,,0.04,,b,0.27,0.57,4.02,,63.29,HPO,-1.05267,0.111618,0.00218083,0.610318 kka2_1:4_W69R,kka2_1:4_69,Kka2,kka2_1:4,P00552,0.610395,NO,69,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-0.859,-4.184,3.325,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.168804,0.0012874,0.610395 kka2_1:8_T51E,kka2_1:8_51,Kka2,kka2_1:8,P00552,0.610422,NO,51,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.199,-3.693,1.494,,0.05,E,B,0.82,-0.05,5.399,,63.64,BPA,-1.76767,0.100394,0.00628861,0.610422 kka2_1:8_T51E,kka2_1:8_51,Kka2,kka2_1:8,P00552,0.610422,NO,51,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.199,-3.693,1.494,,0.05,E,B,0.82,-0.05,5.399,,63.64,BPA,-1.76767,0.100394,0.00628861,0.610422 kka2_1:1_H135D,kka2_1:1_135,Kka2,kka2_1:1,P00552,0.610423,NO,135,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-1.331,-3.636,2.305,,0.071,.,a,0.17,0.65,3.574,,53.03,ABP,-1.77367,0.520039,0.00532566,0.610423 kka2_1:1_A71G,kka2_1:1_71,Kka2,kka2_1:1,P00552,0.610473,NO,71,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.824,-2.399,0.575,,0.553,H,A,0.46,0.08,9.788,,64.39,HHP,-1.74033,0.520039,0.00727707,0.610473 beta-lactamase_625_S201V,beta-lactamase_625_201,TEM-1,beta-lactamase_625,P62593,0.610581,NO,201,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.183,-3.482,2.299,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.213352,0.00198815,0.610581 beta-lactamase_156_Y44C,beta-lactamase_156_44,TEM-1,beta-lactamase_156,P62593,0.610615,NO,44,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-2.547,-4.829,2.282,,,E,B,0.21,-0.45,2.184,,73.78,OHH,-1.86267,0.111618,0.00426364,0.610615 kka2_1:2_D52R,kka2_1:2_52,Kka2,kka2_1:2,P00552,0.610615,NO,52,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.271,-3.572,1.301,,0.22,E,B,0.75,0.8,1.123,,71.59,PAH,-2.38367,0.295029,0.00175694,0.610615 gb1_V265Q,gb1_265,gb1,gb1,P06654,0.610737,NO,265,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.843,-3.929,2.086,,,,,,,0.402,,11.83,OHA,-1.64567,0.177985,0.00360613,0.610737 kka2_1:1_H124R,kka2_1:1_124,Kka2,kka2_1:1,P00552,0.610757,NO,124,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-0.84,-3.511,2.671,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.520039,0.00211296,0.610757 kka2_1:2_M178G,kka2_1:2_178,Kka2,kka2_1:2,P00552,0.610776,NO,178,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-3.206,-2.978,-0.228,,0.554,.,b,0.55,0.68,3.152,,71.59,BHO,-2.154,0.295029,0.00717253,0.610776 beta-lactamase_625_I285G,beta-lactamase_625_285,TEM-1,beta-lactamase_625,P62593,0.610802,NO,285,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.213352,0.101555,0.610802 beta-lactamase_2500_L74A,beta-lactamase_2500_74,TEM-1,beta-lactamase_2500,P62593,0.610827,NO,74,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.296,-1.569,0.273,,,H,A,0.55,-0.91,0.746,,50,HHO,-1.34933,0.361275,0.00493255,0.610827 beta-lactamase_156_R242Y,beta-lactamase_156_242,TEM-1,beta-lactamase_156,P62593,0.610837,NO,242,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.111618,0.00452879,0.610837 beta-lactamase_M153D,beta-lactamase_153,TEM-1,beta-lactamase,P62593,0.610943,NO,153,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-3.193,-3.931,0.738,5.46509,0.14,T,A,1.07,-0.11,2.061,,77.62,PHO,-2.25767,0.221079,0.00509109,0.610943 kka2_1:8_D190L,kka2_1:8_190,Kka2,kka2_1:8,P00552,0.61096,NO,190,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.708,-3.836,3.128,,0.213,S,b,0.29,-0.82,,,,OAH,-0.711667,0.100394,0.00247989,0.61096 kka2_1:8_D190L,kka2_1:8_190,Kka2,kka2_1:8,P00552,0.61096,NO,190,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.708,-3.836,3.128,,0.213,S,b,0.29,-0.82,,,,OAH,-0.711667,0.100394,0.00247989,0.61096 kka2_1:1_S40I,kka2_1:1_40,Kka2,kka2_1:1,P00552,0.610983,NO,40,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.645,-4.1,1.455,,0.32,E,B,0.27,-0.9,25.997,25.997,71.59,HPH,-1.91567,0.520039,0.00693477,0.610983 beta-lactamase_2500_E56L,beta-lactamase_2500_56,TEM-1,beta-lactamase_2500,P62593,0.611034,NO,56,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.043,-3.398,1.355,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.361275,0.00238534,0.611034 kka2_1:2_F37M,kka2_1:2_37,Kka2,kka2_1:2,P00552,0.611101,NO,37,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.427,-4.497,3.07,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.295029,0.00586193,0.611101 kka2_1:2_G30S,kka2_1:2_30,Kka2,kka2_1:2,P00552,0.611128,NO,30,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.596,-3.189,2.593,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.295029,0.00159208,0.611128 kka2_1:1_A191V,kka2_1:1_191,Kka2,kka2_1:1,P00552,0.611132,NO,191,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.831,-3.195,2.364,,,.,b,0.46,-0.94,0.53,,50,AHO,-0.868667,0.520039,0.00338807,0.611132 kka2_1:4_I221S,kka2_1:4_221,Kka2,kka2_1:4,P00552,0.611311,NO,221,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.739,-3.764,2.025,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.168804,0.00945908,0.611311 beta-lactamase_2500_D161S,beta-lactamase_2500_161,TEM-1,beta-lactamase_2500,P62593,0.611362,NO,161,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.891,-2.488,1.597,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.361275,0.000897697,0.611362 kka2_1:1_D238G,kka2_1:1_238,Kka2,kka2_1:1,P00552,0.611399,NO,238,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.83,-2.923,0.093,,0.604,H,A,0.75,-0.33,11.329,11.329,92.05,HAB,-2.633,0.520039,0.0113863,0.611399 beta-lactamase_2500_M153R,beta-lactamase_2500_153,TEM-1,beta-lactamase_2500,P62593,0.611451,NO,153,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-3.193,-4.075,0.882,,0.14,T,A,0.55,-0.11,3.409,,77.62,PHO,-2.25767,0.361275,0.00509109,0.611451 kka2_1:8_E262D,kka2_1:8_262,Kka2,kka2_1:8,P00552,0.611497,NO,262,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-0.829,-2.883,2.054,,0.059,G,A,1.52,-0.18,0.837,,42.42,AAH,-0.816,0.100394,0.0191586,0.611497 kka2_1:8_E262D,kka2_1:8_262,Kka2,kka2_1:8,P00552,0.611497,NO,262,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-0.829,-2.883,2.054,,0.059,G,A,1.52,-0.18,0.837,,42.42,AAH,-0.816,0.100394,0.0191586,0.611497 beta-lactamase_D231L,beta-lactamase_231,TEM-1,beta-lactamase,P62593,0.611532,NO,231,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.816,-3.806,2.99,5.06651,,E,B,1.22,-1.06,0.319,,65.38,HAB,-0.994,0.221079,0.00107395,0.611532 kka2_1:8_D220R,kka2_1:8_220,Kka2,kka2_1:8,P00552,0.611658,NO,220,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.787,-4.005,3.218,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.100394,0.00158066,0.611658 kka2_1:8_D220R,kka2_1:8_220,Kka2,kka2_1:8,P00552,0.611658,NO,220,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.787,-4.005,3.218,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.100394,0.00158066,0.611658 PSD95pdz3_G356P,PSD95pdz3_356,PSD95pdz3,PSD95pdz3,P31016,0.611674,NO,356,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.008,-3.561,2.553,4.8656,,,,,11.9575,,,,BOA,-1.22933,0.0758425,0.000623061,0.611674 kka2_1:4_K50T,kka2_1:4_50,Kka2,kka2_1:4,P00552,0.611704,NO,50,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-0.833,-3.473,2.64,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.168804,0.00138626,0.611704 kka2_1:4_H188L,kka2_1:4_188,Kka2,kka2_1:4,P00552,0.611718,NO,188,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-0.913,-3.61,2.697,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.168804,0.00273139,0.611718 beta-lactamase_39_L74P,beta-lactamase_39_74,TEM-1,beta-lactamase_39,P62593,0.611789,NO,74,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.296,-4.001,2.705,,,H,A,0.55,-0.91,1.581,,50,HHO,-1.34933,0.0495842,0.00493255,0.611789 beta-lactamase_V117F,beta-lactamase_117,TEM-1,beta-lactamase,P62593,0.6118,NO,117,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.53,-3.756,2.226,5.33594,,H,A,1.19,-0.34,1.182,,65.03,PHB,-1.741,0.221079,0.00467906,0.6118 beta-lactamase_2500_A183P,beta-lactamase_2500_183,TEM-1,beta-lactamase_2500,P62593,0.611846,NO,183,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.231,-3.812,2.581,,0.155,H,A,0.46,-0.91,12.189,,77.62,HHH,-1.53367,0.361275,0.00296631,0.611846 kka2_1:1_G30V,kka2_1:1_30,Kka2,kka2_1:1,P00552,0.611848,NO,30,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.596,-3.782,3.186,,0.54,S,g,0.29,3.76,,,,HOO,-1.51133,0.520039,0.00159208,0.611848 kka2_1:2_D33Y,kka2_1:2_33,Kka2,kka2_1:2,P00552,0.611867,NO,33,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.186,-4.503,2.317,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.295029,0.00633568,0.611867 kka2_1:1_W24G,kka2_1:1_24,Kka2,kka2_1:1,P00552,0.611871,NO,24,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-1.779,-3.736,1.957,,0.477,E,B,0.47,-0.21,2.375,,56.06,AHH,-2.24467,0.520039,0.00631564,0.611871 kka2_1:8_D220G,kka2_1:8_220,Kka2,kka2_1:8,P00552,0.611872,NO,220,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.787,-3.222,2.435,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.100394,0.00158066,0.611872 kka2_1:8_D220G,kka2_1:8_220,Kka2,kka2_1:8,P00552,0.611872,NO,220,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.787,-3.222,2.435,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.100394,0.00158066,0.611872 kka2_1:1_A9R,kka2_1:1_9,Kka2,kka2_1:1,P00552,0.611875,NO,9,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.079,-3.835,1.756,,,,,,,0.383,,71.59,BHO,-2.253,0.520039,0.00273264,0.611875 kka2_1:2_G99D,kka2_1:2_99,Kka2,kka2_1:2,P00552,0.611944,NO,99,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.596,-3.497,2.901,,0.368,S,g,0.29,-0.87,,,,OOP,-1.63067,0.295029,0.00186055,0.611944 kka2_1:2_P76D,kka2_1:2_76,Kka2,kka2_1:2,P00552,0.612052,NO,76,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.449,-2.541,1.092,,0.331,.,B,0.52,-0.41,0.345,,63.64,HOO,-1.662,0.295029,0.00625685,0.612052 beta-lactamase_2500_P60F,beta-lactamase_2500_60,TEM-1,beta-lactamase_2500,P62593,0.61213,NO,60,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-2.469,-4.292,1.823,,0.256,T,A,0.52,-0.56,1.581,,77.62,BOA,-1.97633,0.361275,0.00521318,0.61213 kka2_1:1_G30A,kka2_1:1_30,Kka2,kka2_1:1,P00552,0.61215,NO,30,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.596,-2.881,2.285,,0.54,S,g,0.29,3.76,,,,HOO,-1.51133,0.520039,0.00159208,0.61215 kka2_1:2_A255R,kka2_1:2_255,Kka2,kka2_1:2,P00552,0.612167,NO,255,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.715,-2.777,1.062,,0.466,H,A,0.46,-0.52,5.144,,65.53,HHH,-1.71267,0.295029,0.0126809,0.612167 kka2_1:4_R121W,kka2_1:4_121,Kka2,kka2_1:4,P00552,0.612176,NO,121,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.552,-5.451,3.899,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.168804,0.00523326,0.612176 beta-lactamase_L219C,beta-lactamase_219,TEM-1,beta-lactamase,P62593,0.612217,NO,219,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.313,-3.103,1.79,5.74153,,I,A,0.84,-0.51,2.321,,74.48,HHB,-1.21533,0.221079,0.00664345,0.612217 kka2_1:1_G233L,kka2_1:1_233,Kka2,kka2_1:1,P00552,0.612253,NO,233,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.748,-3.881,3.133,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.520039,0.00232366,0.612253 kka2_1:4_Y22W,kka2_1:4_22,Kka2,kka2_1:4,P00552,0.612356,NO,22,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-1.583,-4.944,3.361,,0.122,.,B,0.21,-0.8,1.838,,65.53,OHA,-1.80333,0.168804,0.00598977,0.612356 kka2_1:4_C192F,kka2_1:4_192,Kka2,kka2_1:4,P00552,0.612453,NO,192,C,F,CF,Special,Hydrophobic,5.07,3.32051,-1.74949,205,121,165,44,108.5,189.9,81.4,-1.067,-4.014,2.947,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.168804,0.00485428,0.612453 kka2_1:8_D159Y,kka2_1:8_159,Kka2,kka2_1:8,P00552,0.612461,NO,159,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.82,-4.45,3.63,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.100394,0.0030485,0.612461 kka2_1:8_D159Y,kka2_1:8_159,Kka2,kka2_1:8,P00552,0.612461,NO,159,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.82,-4.45,3.63,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.100394,0.0030485,0.612461 beta-lactamase_39_R81P,beta-lactamase_39_81,TEM-1,beta-lactamase_39,P62593,0.612488,NO,81,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.466,-3.949,2.483,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.0495842,0.00499763,0.612488 kka2_1:2_A224E,kka2_1:2_224,Kka2,kka2_1:2,P00552,0.612534,NO,224,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.977,-3.569,2.592,,,H,A,0.46,-1.26,1.646,,63.64,HHP,-1.41033,0.295029,0.00352047,0.612534 beta-lactamase_625_F58G,beta-lactamase_625_58,TEM-1,beta-lactamase_625,P62593,0.612539,NO,58,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-2.914,-3.566,0.652,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.213352,0.00523369,0.612539 kka2_1:1_F133V,kka2_1:1_133,Kka2,kka2_1:1,P00552,0.612571,NO,133,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-0.871,-3.355,2.484,,0.178,.,B,0.58,0.43,1.999,,42.42,OHA,-0.871667,0.520039,0.00182168,0.612571 kka2_1:4_H188P,kka2_1:4_188,Kka2,kka2_1:4,P00552,0.612622,NO,188,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-0.913,-3.906,2.993,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.168804,0.00273139,0.612622 beta-lactamase_156_G142F,beta-lactamase_156_142,TEM-1,beta-lactamase_156,P62593,0.612631,NO,142,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.707,-4.29,3.583,,0.034,,p,0.29,-0.64,0.325,,64.69,OOO,-0.834,0.111618,0.00060149,0.612631 beta-lactamase_156_G240T,beta-lactamase_156_240,TEM-1,beta-lactamase_156,P62593,0.612653,NO,240,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.111618,0.00591201,0.612653 kka2_1:2_A215E,kka2_1:2_215,Kka2,kka2_1:2,P00552,0.612674,NO,215,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.968,-3.495,2.527,,0.039,E,B,0.46,-0.59,2.137,,50.38,HHA,-1.00467,0.295029,0.00529129,0.612674 kka2_1:1_I207V,kka2_1:1_207,Kka2,kka2_1:1,P00552,0.61277,NO,207,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.175,-1.613,0.438,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.520039,0.00611824,0.61277 kka2_1:2_P179Y,kka2_1:2_179,Kka2,kka2_1:2,P00552,0.612828,NO,179,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.974,-4.379,3.405,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.295029,0.00298346,0.612828 beta-lactamase_E195L,beta-lactamase_195,TEM-1,beta-lactamase,P62593,0.612859,NO,195,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.186,-3.741,1.555,7.28489,1.016,S,A,1.52,0.85,2.583,,77.62,OAH,-2.02,0.221079,0.00496565,0.612859 Ubiquitin_G10A,Ubiquitin_10,Uba1,Ubiquitin,P0CG48,0.612903,NO,10,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.396,-2.48,1.084,5.29806,0.115,S,l,,0.2,,,,POB,-1.38633,0.205827,0.000748953,0.612903 Ubiquitin_H68Y,Ubiquitin_68,Uba1,Ubiquitin,P0CG48,0.612903,NO,68,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-1.869,-2.512,0.643,4.81902,0.194,E,B,0.72,-1.02,21.325,21.325,65.11,HBH,-1.583,0.205827,0.000925438,0.612903 Ubiquitin_I13H,Ubiquitin_13,Uba1,Ubiquitin,P0CG48,0.612903,NO,13,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.554,-4.764,3.21,5.19411,0.038,E,B,,-0.2,,,,PHP,-1.48,0.205827,0.000716423,0.612903 Ubiquitin_K11F,Ubiquitin_11,Uba1,Ubiquitin,P0CG48,0.612903,NO,11,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.354,-4.203,2.849,5.16813,0.401,,B,2.81,0.84,0.335,,25.84,OBP,-1.346,0.205827,0.000535553,0.612903 Ubiquitin_L69H,Ubiquitin_69,Uba1,Ubiquitin,P0CG48,0.612903,NO,69,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.445,-3.197,1.752,4.75624,0.051,E,B,2.89,-0.94,7.106,,34.31,BHH,-1.72933,0.205827,0.000919136,0.612903 Ubiquitin_L69Y,Ubiquitin_69,Uba1,Ubiquitin,P0CG48,0.612903,NO,69,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.445,-3.975,2.53,4.75624,0.051,E,B,2.89,-0.94,7.106,,34.31,BHH,-1.72933,0.205827,0.000919136,0.612903 Ubiquitin_R72G,Ubiquitin_72,Uba1,Ubiquitin,P0CG48,0.612903,NO,72,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.034,-2.808,0.774,5.19484,0.077,,B,1.41,-0.1,9.638,9.638,42.77,HBH,-1.82733,0.205827,0.000768249,0.612903 kka2_1:1_Q163A,kka2_1:1_163,Kka2,kka2_1:1,P00552,0.613199,NO,163,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.162,-2.603,0.441,,0.58,T,B,0.64,1.85,2.779,,64.02,BPO,-1.78333,0.520039,0.00719507,0.613199 beta-lactamase_2500_C121M,beta-lactamase_2500_121,TEM-1,beta-lactamase_2500,P62593,0.613211,NO,121,C,M,CM,Special,Hydrophobic,5.07,5.74,0.67,196,121,149,28,108.5,162.9,54.4,-0.953,-4.506,3.553,,,H,A,0.46,-0.81,1.174,,63.29,HOP,-1.46767,0.361275,0.000744322,0.613211 kka2_1:1_Y257C,kka2_1:1_257,Kka2,kka2_1:1,P00552,0.613219,NO,257,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-1.064,-4.949,3.885,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.520039,0.0148191,0.613219 kka2_1:1_G74C,kka2_1:1_74,Kka2,kka2_1:1,P00552,0.613222,NO,74,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.18,-5.237,4.057,,0.621,T,l,0.75,0.2,15.356,15.356,64.39,POH,-1.91667,0.520039,0.00587035,0.613222 kka2_1:2_P132L,kka2_1:2_132,Kka2,kka2_1:2,P00552,0.613224,NO,132,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.775,-3.61,2.835,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.295029,0.0018489,0.613224 kka2_1:4_K112M,kka2_1:4_112,Kka2,kka2_1:4,P00552,0.613228,NO,112,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-2.491,-4.49,1.999,,0.076,H,A,2.34,-1.37,0.39,,56.06,ABH,-2.00133,0.168804,0.00645389,0.613228 beta-lactamase_P181I,beta-lactamase_181,TEM-1,beta-lactamase,P62593,0.613248,NO,181,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.813,-3.974,3.161,5.14752,,H,A,1.1,-1.14,1.357,,61.54,HOH,-1.795,0.221079,0.000703122,0.613248 kka2_1:2_Q252L,kka2_1:2_252,Kka2,kka2_1:2,P00552,0.613282,NO,252,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.63,-3.66,1.03,,0.906,H,A,0.64,0.35,5.613,,92.05,PPB,-2.20733,0.295029,0.0121001,0.613282 beta-lactamase_625_R257T,beta-lactamase_625_257,TEM-1,beta-lactamase_625,P62593,0.613367,NO,257,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.213352,0.00756629,0.613367 beta-lactamase_156_E87P,beta-lactamase_156_87,TEM-1,beta-lactamase_156,P62593,0.613385,NO,87,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.421,-3.872,2.451,,0.048,,B,1.04,0.92,1.754,,64.69,PAP,-1.969,0.111618,0.00337888,0.613385 kka2_1:8_D127F,kka2_1:8_127,Kka2,kka2_1:8,P00552,0.613529,NO,127,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.364,-4.509,3.145,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.100394,0.00660501,0.613529 kka2_1:8_D127F,kka2_1:8_127,Kka2,kka2_1:8,P00552,0.613529,NO,127,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.364,-4.509,3.145,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.100394,0.00660501,0.613529 kka2_1:2_P128R,kka2_1:2_128,Kka2,kka2_1:2,P00552,0.613536,NO,128,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.922,-4.235,2.313,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.295029,0.00774689,0.613536 beta-lactamase_156_T116W,beta-lactamase_156_116,TEM-1,beta-lactamase_156,P62593,0.613543,NO,116,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.28,-5.356,4.076,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.111618,0.00336175,0.613543 kka2_1:1_R217G,kka2_1:1_217,Kka2,kka2_1:1,P00552,0.61355,NO,217,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.158,-3.574,2.416,,0.252,T,A,1.2,-0.59,0.381,,52.27,ABH,-1.127,0.520039,0.0047191,0.61355 beta-lactamase_0_S221I,beta-lactamase_0_221,TEM-1,beta-lactamase_0,P62593,0.613604,NO,221,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.754,-3.812,2.058,,0.624,H,A,0.27,-0.2,2.914,,74.48,BPH,-1.59967,0.0500837,0.0046094,0.613604 beta-lactamase_0_D48W,beta-lactamase_0_48,TEM-1,beta-lactamase_0,P62593,0.613693,NO,48,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.101,-5.502,4.401,,0.189,E,B,0.75,0.21,17.825,17.825,50.35,HAH,-1.62467,0.0500837,0.0027273,0.613693 beta-lactamase_2500_R63Y,beta-lactamase_2500_63,TEM-1,beta-lactamase_2500,P62593,0.613739,NO,63,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-0.943,-4.16,3.217,,0.218,,B,1.2,-0.31,0.929,,44.06,ABH,-0.992333,0.361275,0.00126938,0.613739 beta-lactamase_P224L,beta-lactamase_224,TEM-1,beta-lactamase,P62593,0.61382,NO,224,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.893,-3.582,2.689,5.179,0.383,,B,0.99,-0.3,0.383,,74.48,HOH,-1.26433,0.221079,0.00189564,0.61382 beta-lactamase_625_L146T,beta-lactamase_625_146,TEM-1,beta-lactamase_625,P62593,0.613849,NO,146,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.462,-3.533,2.071,,0.007,H,A,0.55,-0.56,2.16,,64.69,AHP,-1.656,0.213352,0.00474542,0.613849 kka2_1:2_L193D,kka2_1:2_193,Kka2,kka2_1:2,P00552,0.613863,NO,193,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.983,-4.051,3.068,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.295029,0.00480179,0.613863 beta-lactamase_D174P,beta-lactamase_174,TEM-1,beta-lactamase,P62593,0.613879,NO,174,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.738,-3.655,2.917,5.44133,0.238,,B,1.22,-0.1,,,,PAA,-1.91233,0.221079,0.00125633,0.613879 beta-lactamase_2500_M270D,beta-lactamase_2500_270,TEM-1,beta-lactamase_2500,P62593,0.61396,NO,270,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.723,,,,0.422,H,A,1.59,1.15,2.029,,64.34,PHA,-1.70933,0.361275,0.00767762,0.61396 beta-lactamase_S264L,beta-lactamase_264,TEM-1,beta-lactamase,P62593,0.613974,NO,264,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.985,-3.35,1.365,4.67475,0.04,,B,0.25,0.29,34.251,34.251,73.78,OPP,-2.19867,0.221079,0.0119399,0.613974 kka2_1:2_L193P,kka2_1:2_193,Kka2,kka2_1:2,P00552,0.613995,NO,193,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.983,-2.872,1.889,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.295029,0.00480179,0.613995 kka2_1:1_T51D,kka2_1:1_51,Kka2,kka2_1:1,P00552,0.614007,NO,51,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.199,-3.85,1.651,,0.05,E,B,0.22,-0.05,3.056,,63.64,BPA,-1.76767,0.520039,0.00628861,0.614007 kka2_1:4_N200V,kka2_1:4_200,Kka2,kka2_1:4,P00552,0.614007,NO,200,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-2.446,-3.862,1.416,,0.756,T,L,0.61,-0.08,1.746,,64.39,APO,-2.08,0.168804,0.00838549,0.614007 beta-lactamase_L188G,beta-lactamase_188,TEM-1,beta-lactamase,P62593,0.614058,NO,188,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.166,-3.699,2.533,5.55434,,H,A,1.07,-0.3,1.574,,60.14,PHB,-1.47033,0.221079,0.00295687,0.614058 kka2_1:2_D134S,kka2_1:2_134,Kka2,kka2_1:2,P00552,0.61406,NO,134,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.969,-2.62,1.651,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.295029,0.00270812,0.61406 beta-lactamase_0_R273K,beta-lactamase_0_273,TEM-1,beta-lactamase_0,P62593,0.61415,NO,273,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.314,-2.204,-0.11,,0.564,H,A,1.2,1.57,20.248,20.248,73.78,ABP,-1.841,0.0500837,0.0077952,0.61415 beta-lactamase_625_S266D,beta-lactamase_625_266,TEM-1,beta-lactamase_625,P62593,0.614167,NO,266,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.213352,0.0140785,0.614167 beta-lactamase_R63W,beta-lactamase_63,TEM-1,beta-lactamase,P62593,0.614227,NO,63,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-0.943,-5.32,4.377,5.49979,0.218,,B,0.45,-0.31,0.677,,44.06,ABH,-0.992333,0.221079,0.00126938,0.614227 kka2_1:1_P12L,kka2_1:1_12,Kka2,kka2_1:1,P00552,0.614234,NO,12,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.853,-3.533,2.68,,,.,B,0.52,1.25,0.261,,48.11,POH,-1.80767,0.520039,0.00500011,0.614234 kka2_1:2_S54W,kka2_1:2_54,Kka2,kka2_1:2,P00552,0.614245,NO,54,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.471,-5.559,3.088,,0.408,S,b,0.27,1.01,0.393,,71.59,HPO,-2.259,0.295029,0.00782867,0.614245 beta-lactamase_2500_E56M,beta-lactamase_2500_56,TEM-1,beta-lactamase_2500,P62593,0.614332,NO,56,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.043,-4.624,2.581,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.361275,0.00238534,0.614332 beta-lactamase_M66Y,beta-lactamase_66,TEM-1,beta-lactamase,P62593,0.614372,NO,66,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.362,-4.034,2.672,5.29561,0.013,,A,1.3,-0.7,1.319,,73.08,OHH,-1.49567,0.221079,0.00412876,0.614372 kka2_1:2_E230K,kka2_1:2_230,Kka2,kka2_1:2,P00552,0.614376,NO,230,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.672,-3.648,0.976,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.295029,0.00920051,0.614376 kka2_1:1_I221V,kka2_1:1_221,Kka2,kka2_1:1,P00552,0.614463,NO,221,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.739,-2.261,0.522,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.520039,0.00945908,0.614463 PSD95pdz3_V386F,PSD95pdz3_386,PSD95pdz3,PSD95pdz3,P31016,0.614479,NO,386,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.465,-3.524,2.059,5.18836,,,,,17.5429,,,,PHP,-1.463,0.0758425,0.000184509,0.614479 kka2_1:8_F264V,kka2_1:8_264,Kka2,kka2_1:8,P00552,0.614487,NO,264,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.02,-3.361,2.341,,0.296,,?,1.62,0.02,1.553,,71.59,HHO,-0.9655,0.100394,,0.614487 kka2_1:8_F264V,kka2_1:8_264,Kka2,kka2_1:8,P00552,0.614487,NO,264,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.02,-3.361,2.341,,0.296,,?,1.62,0.02,1.553,,71.59,HHO,-0.9655,0.100394,,0.614487 beta-lactamase_625_R242H,beta-lactamase_625_242,TEM-1,beta-lactamase_625,P62593,0.614506,NO,242,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.213352,0.00452879,0.614506 beta-lactamase_2500_I54S,beta-lactamase_2500_54,TEM-1,beta-lactamase_2500,P62593,0.614577,NO,54,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-2.838,-3.459,0.621,,0.669,E,B,0.48,-0.14,3.946,,73.78,BHH,-2.337,0.361275,0.00403589,0.614577 beta-lactamase_0_V42F,beta-lactamase_0_42,TEM-1,beta-lactamase_0,P62593,0.614582,NO,42,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.564,-3.895,2.331,,0.017,E,B,0.44,-0.51,1.659,,63.99,BHO,-1.042,0.0500837,0.00404515,0.614582 kka2_1:2_H162R,kka2_1:2_162,Kka2,kka2_1:2,P00552,0.614632,NO,162,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-2.319,-1.245,-1.074,,0.071,G,A,0.17,1.01,3.187,,64.39,ABP,-2.02067,0.295029,0.00616145,0.614632 beta-lactamase_T198W,beta-lactamase_198,TEM-1,beta-lactamase,P62593,0.614731,NO,198,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.168,-5.419,3.251,4.9209,0.489,,B,0.69,-0.13,0.37,,73.78,HPH,-1.98767,0.221079,0.004311,0.614731 kka2_1:4_Y257W,kka2_1:4_257,Kka2,kka2_1:4,P00552,0.614839,NO,257,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-1.064,-4.353,3.289,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.168804,0.0148191,0.614839 beta-lactamase_2500_A124G,beta-lactamase_2500_124,TEM-1,beta-lactamase_2500,P62593,0.614871,NO,124,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.181,-3.186,2.005,,,H,A,0.46,-0.9,0.314,,64.34,HHH,-1.152,0.361275,0.00481399,0.614871 beta-lactamase_0_D174Y,beta-lactamase_0_174,TEM-1,beta-lactamase_0,P62593,0.614924,NO,174,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.738,-4.387,3.649,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.0500837,0.00125633,0.614924 kka2_1:1_R217S,kka2_1:1_217,Kka2,kka2_1:1,P00552,0.614933,NO,217,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.158,-3.548,2.39,,0.252,T,A,1.2,-0.59,0.381,,52.27,ABH,-1.127,0.520039,0.0047191,0.614933 kka2_1:2_E111G,kka2_1:2_111,Kka2,kka2_1:2,P00552,0.614956,NO,111,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.28,-2.822,0.542,,0.155,H,A,1.52,-1.14,2.792,,65.53,HAB,-2.27833,0.295029,0.00746789,0.614956 kka2_1:1_D190E,kka2_1:1_190,Kka2,kka2_1:1,P00552,0.614961,NO,190,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.708,-2.793,2.085,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.520039,0.00247989,0.614961 beta-lactamase_D48K,beta-lactamase_48,TEM-1,beta-lactamase,P62593,0.615015,NO,48,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.101,-3.448,2.347,4.89966,0.189,E,B,0.23,0.21,1.281,,50.35,HAH,-1.62467,0.221079,0.0027273,0.615015 kka2_1:4_L107Q,kka2_1:4_107,Kka2,kka2_1:4,P00552,0.615028,NO,107,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.238,-4.215,2.977,,0.197,.,B,0.55,-1.1,0.398,,71.59,BHH,-2.143,0.168804,0.00561937,0.615028 kka2_1:4_L232V,kka2_1:4_232,Kka2,kka2_1:4,P00552,0.615211,NO,232,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.514,-2.443,0.929,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.168804,0.00800103,0.615211 kka2_1:4_A191V,kka2_1:4_191,Kka2,kka2_1:4,P00552,0.615273,NO,191,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.831,-3.195,2.364,,,.,b,0.46,-0.94,2.046,,50,AHO,-0.868667,0.168804,0.00338807,0.615273 kka2_1:2_L184P,kka2_1:2_184,Kka2,kka2_1:2,P00552,0.615289,NO,184,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.496,-2.724,1.228,,0.489,E,B,0.55,-0.06,14.044,14.044,63.26,AHH,-1.24833,0.295029,0.00518742,0.615289 kka2_1:4_H135F,kka2_1:4_135,Kka2,kka2_1:4,P00552,0.615356,NO,135,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-1.331,-4.11,2.779,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.168804,0.00532566,0.615356 WW_domain_L173H,WW_domain_173,Yap65,WW_domain,P46937,0.615408,NO,173,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.117,-4.682,3.565,,,,,,,,,,OHO,-1.06233,0.153962,0.000851849,0.615408 beta-lactamase_L197G,beta-lactamase_197,TEM-1,beta-lactamase,P62593,0.615423,NO,197,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.853,-3.681,2.828,5.19172,0.007,S,B,1.3,0.33,1.756,,60.14,HHP,-1.833,0.221079,0.00144602,0.615423 beta-lactamase_625_G52P,beta-lactamase_625_52,TEM-1,beta-lactamase_625,P62593,0.61544,NO,52,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.149,-2.849,1.7,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.213352,0.00340138,0.61544 kka2_1:1_E199G,kka2_1:1_199,Kka2,kka2_1:1,P00552,0.615489,NO,199,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.234,-3.518,1.284,,0.508,E,B,1.04,-0.43,3.012,,65.53,HAP,-2.133,0.520039,0.00854122,0.615489 beta-lactamase_0_T138F,beta-lactamase_0_138,TEM-1,beta-lactamase_0,P62593,0.615511,NO,138,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.506,-4.444,1.938,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.0500837,0.00487868,0.615511 beta-lactamase_0_A215N,beta-lactamase_0_215,TEM-1,beta-lactamase_0,P62593,0.615645,NO,215,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.503,-3.679,2.176,,,,a,0.46,-0.93,0.494,,74.48,HHO,-1.42633,0.0500837,0.00544007,0.615645 kka2_1:1_V83C,kka2_1:1_83,Kka2,kka2_1:1,P00552,0.615718,NO,83,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-2.567,-5.124,2.557,,0.358,E,B,0.44,0.53,5.931,,71.59,AHH,-2.264,0.520039,0.00650486,0.615718 beta-lactamase_0_T187D,beta-lactamase_0_187,TEM-1,beta-lactamase_0,P62593,0.615733,NO,187,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.401,-2.769,1.368,,0.007,H,A,0.22,-1.19,3.259,,67.48,PPH,-1.69633,0.0500837,0.00491782,0.615733 beta-lactamase_L219D,beta-lactamase_219,TEM-1,beta-lactamase,P62593,0.615741,NO,219,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.313,-4.126,2.813,5.74153,,I,A,0.84,-0.51,2.321,,74.48,HHB,-1.21533,0.221079,0.00664345,0.615741 kka2_1:1_D52N,kka2_1:1_52,Kka2,kka2_1:1,P00552,0.615743,NO,52,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.271,-3.474,1.203,,0.22,E,B,0.75,0.8,2.64,,71.59,PAH,-2.38367,0.520039,0.00175694,0.615743 kka2_1:2_N200A,kka2_1:2_200,Kka2,kka2_1:2,P00552,0.615747,NO,200,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-2.446,-2.325,-0.121,,0.756,T,L,0.61,-0.08,2.836,,64.39,APO,-2.08,0.295029,0.00838549,0.615747 beta-lactamase_39_I277G,beta-lactamase_39_277,TEM-1,beta-lactamase_39,P62593,0.615864,NO,277,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.0495842,0.0169305,0.615864 kka2_1:8_Y244W,kka2_1:8_244,Kka2,kka2_1:8,P00552,0.615884,NO,244,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-0.775,-4.226,3.451,,0.066,H,A,1.25,-0.64,,,,HHO,-1.41267,0.100394,0.00453187,0.615884 kka2_1:8_Y244W,kka2_1:8_244,Kka2,kka2_1:8,P00552,0.615884,NO,244,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-0.775,-4.226,3.451,,0.066,H,A,1.25,-0.64,,,,HHO,-1.41267,0.100394,0.00453187,0.615884 beta-lactamase_625_S266Y,beta-lactamase_625_266,TEM-1,beta-lactamase_625,P62593,0.615926,NO,266,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.213352,0.0140785,0.615926 beta-lactamase_2500_P60W,beta-lactamase_2500_60,TEM-1,beta-lactamase_2500,P62593,0.61597,NO,60,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-2.469,-5.456,2.987,,0.256,T,A,0.52,-0.56,1.581,,77.62,BOA,-1.97633,0.361275,0.00521318,0.61597 kka2_1:4_A222T,kka2_1:4_222,Kka2,kka2_1:4,P00552,0.615972,NO,222,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.725,-3.225,2.5,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.168804,0.00207657,0.615972 kka2_1:8_L93R,kka2_1:8_93,Kka2,kka2_1:8,P00552,0.615972,NO,93,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.815,-2.776,1.961,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.100394,0.00131498,0.615972 kka2_1:8_L93R,kka2_1:8_93,Kka2,kka2_1:8,P00552,0.615972,NO,93,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.815,-2.776,1.961,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.100394,0.00131498,0.615972 beta-lactamase_39_V72N,beta-lactamase_39_72,TEM-1,beta-lactamase_39,P62593,0.616024,NO,72,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.658,-4.143,2.485,,,H,A,0.44,-1.03,1.92,,65.73,BHH,-1.32167,0.0495842,0.00501194,0.616024 gb1_F256T,gb1_256,gb1,gb1,P06654,0.616071,NO,256,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.241,-3.423,2.182,,,,,,,,,,HHB,-2.04767,0.177985,0.00435993,0.616071 kka2_1:8_L170A,kka2_1:8_170,Kka2,kka2_1:8,P00552,0.616187,NO,170,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.28,-2.219,0.939,,0.029,H,A,1.59,0.11,1.453,,62.5,AHH,-1.534,0.100394,0.00730791,0.616187 kka2_1:8_L170A,kka2_1:8_170,Kka2,kka2_1:8,P00552,0.616187,NO,170,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.28,-2.219,0.939,,0.029,H,A,1.59,0.11,1.453,,62.5,AHH,-1.534,0.100394,0.00730791,0.616187 beta-lactamase_156_M209I,beta-lactamase_156_209,TEM-1,beta-lactamase_156,P62593,0.616226,NO,209,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.442,-3.121,1.679,,,H,A,0.55,-0.97,1.066,,64.69,HHA,-1.52633,0.111618,0.00625021,0.616226 kka2_1:1_G201D,kka2_1:1_201,Kka2,kka2_1:1,P00552,0.616292,NO,201,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.56,-2.294,0.734,,0.149,T,l,0.29,-0.57,16.092,16.092,52.65,POB,-1.92233,0.520039,0.00820117,0.616292 beta-lactamase_R220S,beta-lactamase_220,TEM-1,beta-lactamase,P62593,0.61638,NO,220,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-0.942,-3.349,2.407,5.65995,0.295,I,A,0.68,-0.76,2.164,,74.48,HBP,-1.33633,0.221079,0.00232421,0.61638 beta-lactamase_156_L100D,beta-lactamase_156_100,TEM-1,beta-lactamase_156,P62593,0.616402,NO,100,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.218,-4.132,2.914,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.111618,0.00413885,0.616402 beta-lactamase_2500_R63S,beta-lactamase_2500_63,TEM-1,beta-lactamase_2500,P62593,0.616402,NO,63,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-0.943,-3.435,2.492,,0.218,,B,1.2,-0.31,0.929,,44.06,ABH,-0.992333,0.361275,0.00126938,0.616402 kka2_1:1_G55H,kka2_1:1_55,Kka2,kka2_1:1,P00552,0.616423,NO,55,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.625,-2.922,1.297,,0.517,S,b,0.29,1.19,4.035,,63.64,POH,-2.05967,0.520039,0.00667877,0.616423 beta-lactamase_Q37P,beta-lactamase_37,TEM-1,beta-lactamase,P62593,0.616465,NO,37,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.134,-3.965,1.831,5.69153,0.613,H,A,0.12,1.98,1.318,,73.08,APH,-2.06967,0.221079,0.00425833,0.616465 beta-lactamase_625_R273F,beta-lactamase_625_273,TEM-1,beta-lactamase_625,P62593,0.616471,NO,273,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.314,-4.428,2.114,,0.564,H,A,1.2,1.57,1.455,,73.78,ABP,-1.841,0.213352,0.0077952,0.616471 kka2_1:1_R18C,kka2_1:1_18,Kka2,kka2_1:1,P00552,0.616515,NO,18,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.055,-5.174,3.119,,0.474,T,A,1.2,0.54,11.422,11.422,71.59,ABH,-1.821,0.520039,0.00724065,0.616515 kka2_1:4_G213V,kka2_1:4_213,Kka2,kka2_1:4,P00552,0.616536,NO,213,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.596,-3.782,3.186,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.168804,0.00187654,0.616536 kka2_1:2_V113A,kka2_1:2_113,Kka2,kka2_1:2,P00552,0.6167,NO,113,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.233,-2.573,1.34,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.295029,0.00650191,0.6167 beta-lactamase_0_I125K,beta-lactamase_0_125,TEM-1,beta-lactamase_0,P62593,0.616852,NO,125,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.441,-3.825,2.384,,,H,A,0.48,-0.7,1.874,,63.29,HHP,-1.248,0.0500837,0.00383964,0.616852 beta-lactamase_N272V,beta-lactamase_272,TEM-1,beta-lactamase,P62593,0.616866,NO,272,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-1.127,-3.806,2.679,5.37826,0.081,H,A,0.09,-0.97,1.468,,63.64,BPB,-1.56333,0.221079,0.00545371,0.616866 E1_Ubiquitin_L73K,E1_Ubiquitin_73,Uba1,E1_Ubiquitin,P0CG63,0.617153,NO,73,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.039,-3.499,2.46,,0.518,,B,1.3,1,,,,BHB,-1.175,0.18783,0.00111236,0.617153 kka2_1:1_R239K,kka2_1:1_239,Kka2,kka2_1:1,P00552,0.617156,NO,239,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.949,-3.654,0.705,,0.15,H,A,1.2,-0.31,0.477,,71.59,ABH,-2.23,0.520039,0.00835326,0.617156 beta-lactamase_625_T116G,beta-lactamase_625_116,TEM-1,beta-lactamase_625,P62593,0.617169,NO,116,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.28,-3.287,2.007,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.213352,0.00336175,0.617169 kka2_1:8_R44P,kka2_1:8_44,Kka2,kka2_1:8,P00552,0.617187,NO,44,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.062,-4.075,2.013,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.100394,0.00745043,0.617187 kka2_1:8_R44P,kka2_1:8_44,Kka2,kka2_1:8,P00552,0.617187,NO,44,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.062,-4.075,2.013,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.100394,0.00745043,0.617187 beta-lactamase_0_V260K,beta-lactamase_0_260,TEM-1,beta-lactamase_0,P62593,0.617217,NO,260,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.0500837,0.00471757,0.617217 kka2_1:2_P76C,kka2_1:2_76,Kka2,kka2_1:2,P00552,0.617217,NO,76,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.449,-5.046,3.597,,0.331,.,B,0.52,-0.41,0.345,,63.64,HOO,-1.662,0.295029,0.00625685,0.617217 kka2_1:2_G210V,kka2_1:2_210,Kka2,kka2_1:2,P00552,0.617218,NO,210,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.095,-3.659,2.564,,0.103,T,A,0.29,-0.62,0.271,,50,OOB,-0.966667,0.295029,0.00598378,0.617218 hsp90_F583T,hsp90_583,hsp90,hsp90,P02829,0.617221,NO,583,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-3.22,-2.8,0,5.28185,1.112,S,l,1.1,0.87,,,,PHO,-3.003,0.368192,0.000222939,0.617221 beta-lactamase_2500_N168T,beta-lactamase_2500_168,TEM-1,beta-lactamase_2500,P62593,0.617246,NO,168,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-1.029,-2.214,1.185,,0.113,G,A,0.61,-0.4,2.9,,44.41,HPA,-1.13233,0.361275,0.00288667,0.617246 beta-lactamase_0_H151P,beta-lactamase_0_151,TEM-1,beta-lactamase_0,P62593,0.617271,NO,151,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-2.96,-3.911,0.951,,0.594,H,A,0.17,0.1,9.375,,77.62,HBP,-2.34767,0.0500837,0.00216946,0.617271 beta-lactamase_2500_T126N,beta-lactamase_2500_126,TEM-1,beta-lactamase_2500,P62593,0.617315,NO,126,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.122,-3.467,2.345,,0.05,H,A,0.22,-0.05,0.817,,44.41,HPH,-1.60467,0.361275,0.00244552,0.617315 beta-lactamase_D231V,beta-lactamase_231,TEM-1,beta-lactamase,P62593,0.617357,NO,231,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.816,-3.751,2.935,5.06651,,E,B,1.22,-1.06,0.319,,65.38,HAB,-0.994,0.221079,0.00107395,0.617357 kka2_1:4_K138E,kka2_1:4_138,Kka2,kka2_1:4,P00552,0.61739,NO,138,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-2.5,-1.783,-0.717,,0.594,H,A,1.3,0.98,21.267,21.267,71.59,HBB,-2.48833,0.168804,0.00628542,0.61739 beta-lactamase_2500_T147H,beta-lactamase_2500_147,TEM-1,beta-lactamase_2500,P62593,0.617395,NO,147,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.149,-4.643,3.494,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.361275,0.00226017,0.617395 kka2_1:8_R66H,kka2_1:8_66,Kka2,kka2_1:8,P00552,0.617398,NO,66,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-0.922,-4.322,3.4,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.100394,0.00161025,0.617398 kka2_1:8_R66H,kka2_1:8_66,Kka2,kka2_1:8,P00552,0.617398,NO,66,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-0.922,-4.322,3.4,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.100394,0.00161025,0.617398 beta-lactamase_2500_G226Y,beta-lactamase_2500_226,TEM-1,beta-lactamase_2500,P62593,0.617426,NO,226,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.461,-4.462,3.001,,0.701,T,l,0.29,-0.25,5.086,,74.48,HOH,-1.42933,0.361275,0.00665294,0.617426 Pab1_S154T,Pab1_154,Pab1,Pab1,P04147,0.617443,NO,154,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.146,-2.789,1.643,,0.208,E,B,0.1,-0.75,,,,HPP,-1.408,0.175299,0.000319331,0.617443 kka2_1:1_D154Y,kka2_1:1_154,Kka2,kka2_1:1,P00552,0.617449,NO,154,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.876,-4.417,3.541,,0.457,.,b,0.75,1.48,0.658,,52.65,HAP,-1.52467,0.520039,0.00292633,0.617449 beta-lactamase_625_G154V,beta-lactamase_625_154,TEM-1,beta-lactamase_625,P62593,0.617451,NO,154,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.823,-3.725,2.902,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.213352,0.00180205,0.617451 kka2_1:1_P45T,kka2_1:1_45,Kka2,kka2_1:1,P00552,0.617524,NO,45,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.774,-2.639,0.865,,0.669,.,B,0.52,-0.76,4.882,,71.59,BOH,-2.152,0.520039,0.00590481,0.617524 beta-lactamase_2500_A34Q,beta-lactamase_2500_34,TEM-1,beta-lactamase_2500,P62593,0.61758,NO,34,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.059,-4.16,2.101,,,H,A,0.46,-0.54,2.921,,73.78,AHA,-1.74967,0.361275,0.00407913,0.61758 kka2_1:2_E96R,kka2_1:2_96,Kka2,kka2_1:2,P00552,0.617622,NO,96,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.573,-2.69,0.117,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.295029,0.00369441,0.617622 kka2_1:4_D220G,kka2_1:4_220,Kka2,kka2_1:4,P00552,0.617667,NO,220,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.787,-3.222,2.435,,,H,A,0.75,-1.14,1.237,,46.59,PAH,-1.152,0.168804,0.00158066,0.617667 kka2_1:1_R89L,kka2_1:1_89,Kka2,kka2_1:1,P00552,0.617712,NO,89,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.548,-3.591,2.043,,0.209,E,B,0.16,1.41,14.396,14.396,64.39,OBA,-1.89867,0.520039,0.00524373,0.617712 kka2_1:2_A64G,kka2_1:2_64,Kka2,kka2_1:2,P00552,0.617756,NO,64,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.496,-2.776,1.28,,0.039,H,A,0.46,-0.57,14.509,14.509,56.06,AHH,-1.334,0.295029,0.00705578,0.617756 gb1_K254T,gb1_254,gb1,gb1,P06654,0.617811,NO,254,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.748,-3.287,1.539,,,,,,,1.793,,37.28,ABH,-2.195,0.177985,0.00622711,0.617811 beta-lactamase_A215Y,beta-lactamase_215,TEM-1,beta-lactamase,P62593,0.617817,NO,215,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.503,-4.339,2.836,4.82164,,,a,0.75,-0.93,3.583,,74.48,HHO,-1.42633,0.221079,0.00544007,0.617817 kka2_1:1_V185A,kka2_1:1_185,Kka2,kka2_1:1,P00552,0.617833,NO,185,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.045,-2.271,1.226,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.520039,0.00367031,0.617833 kka2_1:2_D190A,kka2_1:2_190,Kka2,kka2_1:2,P00552,0.617961,NO,190,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.708,-3.331,2.623,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.295029,0.00247989,0.617961 kka2_1:2_D134Y,kka2_1:2_134,Kka2,kka2_1:2,P00552,0.618002,NO,134,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.969,-4.401,3.432,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.295029,0.00270812,0.618002 kka2_1:2_G10H,kka2_1:2_10,Kka2,kka2_1:2,P00552,0.61813,NO,10,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.921,-4.434,2.513,,,,,,,2.192,,71.59,HOP,-2.10733,0.295029,0.00289233,0.61813 kka2_1:1_G205C,kka2_1:1_205,Kka2,kka2_1:1,P00552,0.61816,NO,205,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.596,-5.115,4.519,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.520039,0.00221855,0.61816 beta-lactamase_P249W,beta-lactamase_249,TEM-1,beta-lactamase,P62593,0.618183,NO,249,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.312,-5.528,4.216,5.10655,0.256,S,B,0.99,0.04,0.479,,72.73,OOA,-1.81367,0.221079,0.00220169,0.618183 kka2_1:1_H139R,kka2_1:1_139,Kka2,kka2_1:1,P00552,0.618326,NO,139,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-2.809,-2.657,-0.152,,0.471,H,A,0.17,0.68,1.153,,63.64,BBB,-2.22,0.520039,0.00734779,0.618326 PSD95pdz3_L349P,PSD95pdz3_349,PSD95pdz3,PSD95pdz3,P31016,0.618336,NO,349,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.347,-3.786,2.439,5.14696,,,,,24.6438,,,,AHP,-1.37667,0.0758425,0.00071841,0.618336 kka2_1:1_E59K,kka2_1:1_59,Kka2,kka2_1:1,P00552,0.618394,NO,59,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-0.952,-3.163,2.211,,0.187,.,L,1.04,0.62,2.648,,50.38,PAH,-1.53,0.520039,0.00280355,0.618394 kka2_1:2_A119S,kka2_1:2_119,Kka2,kka2_1:2,P00552,0.61852,NO,119,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.073,-2.181,1.108,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.295029,0.00441074,0.61852 beta-lactamase_625_I261Y,beta-lactamase_625_261,TEM-1,beta-lactamase_625,P62593,0.618523,NO,261,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.213352,0.0123091,0.618523 WW_domain_L173P,WW_domain_173,Yap65,WW_domain,P46937,0.618548,NO,173,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.117,-3.882,2.765,,,,,,,,,,OHO,-1.06233,0.153962,0.000851849,0.618548 kka2_1:1_A64V,kka2_1:1_64,Kka2,kka2_1:1,P00552,0.618633,NO,64,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.496,-1.905,0.409,,0.039,H,A,0.46,-0.57,1.175,,56.06,AHH,-1.334,0.520039,0.00705578,0.618633 beta-lactamase_625_D83M,beta-lactamase_625_83,TEM-1,beta-lactamase_625,P62593,0.618652,NO,83,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.066,-4.912,3.846,,0.354,H,A,0.75,0.22,0.239,,48.95,HAH,-1.34733,0.213352,0.00205968,0.618652 beta-lactamase_156_W288V,beta-lactamase_156_288,TEM-1,beta-lactamase_156,P62593,0.618857,NO,288,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,,,,,,,,,,,,,BHO,,0.111618,,0.618857 kka2_1:8_C209F,kka2_1:8_209,Kka2,kka2_1:8,P00552,0.61887,NO,209,C,F,CF,Special,Hydrophobic,5.07,3.32051,-1.74949,205,121,165,44,108.5,189.9,81.4,-0.906,-4.063,3.157,,,,a,1.5,-0.89,0.391,,19.32,AOO,-0.903,0.100394,0.00260862,0.61887 kka2_1:8_C209F,kka2_1:8_209,Kka2,kka2_1:8,P00552,0.61887,NO,209,C,F,CF,Special,Hydrophobic,5.07,3.32051,-1.74949,205,121,165,44,108.5,189.9,81.4,-0.906,-4.063,3.157,,,,a,1.5,-0.89,0.391,,19.32,AOO,-0.903,0.100394,0.00260862,0.61887 kka2_1:1_S204G,kka2_1:1_204,Kka2,kka2_1:1,P00552,0.618887,NO,204,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.353,-2.544,1.191,,0.144,E,A,0.27,-1.2,3.022,,65.53,HPO,-0.953333,0.520039,0.00881794,0.618887 beta-lactamase_P65C,beta-lactamase_65,TEM-1,beta-lactamase,P62593,0.618967,NO,65,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.894,-5.01,4.116,5.59094,0.098,E,B,0.23,-0.62,0.623,,40.56,HOH,-1.03233,0.221079,0.00152776,0.618967 beta-lactamase_0_D161A,beta-lactamase_0_161,TEM-1,beta-lactamase_0,P62593,0.61897,NO,161,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.891,-3.235,2.344,,0.341,,A,0.75,-0.52,0.795,,61.19,HAB,-0.961333,0.0500837,0.000897697,0.61897 kka2_1:2_P98N,kka2_1:2_98,Kka2,kka2_1:2,P00552,0.619003,NO,98,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.526,-3.852,2.326,,0.391,S,B,0.52,-0.65,2.82,,63.26,HOO,-1.19167,0.295029,0.00622754,0.619003 beta-lactamase_0_G52Y,beta-lactamase_0_52,TEM-1,beta-lactamase_0,P62593,0.619066,NO,52,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.149,-4.436,3.287,,0.299,,l,0.29,-0.04,1.164,,64.69,POB,-1.66267,0.0500837,0.00340138,0.619066 beta-lactamase_625_Y262T,beta-lactamase_625_262,TEM-1,beta-lactamase_625,P62593,0.61908,NO,262,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-1.332,-4.271,2.939,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.213352,0.00853516,0.61908 beta-lactamase_D161Y,beta-lactamase_161,TEM-1,beta-lactamase,P62593,0.619088,NO,161,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.891,-4.387,3.496,5.12208,0.341,,A,0.23,-0.52,1.602,,61.19,HAB,-0.961333,0.221079,0.000897697,0.619088 beta-lactamase_625_P224M,beta-lactamase_625_224,TEM-1,beta-lactamase_625,P62593,0.619116,NO,224,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.893,-4.704,3.811,,0.383,,B,0.52,-0.3,1.35,,74.48,HOH,-1.26433,0.213352,0.00189564,0.619116 kka2_1:2_A255L,kka2_1:2_255,Kka2,kka2_1:2,P00552,0.619126,NO,255,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.715,-3.015,1.3,,0.466,H,A,0.46,-0.52,5.144,,65.53,HHH,-1.71267,0.295029,0.0126809,0.619126 kka2_1:1_A150E,kka2_1:1_150,Kka2,kka2_1:1,P00552,0.61915,NO,150,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.949,-2.676,1.727,,0.544,T,A,0.46,1.34,2.333,,63.26,AHO,-1.272,0.520039,0.0045009,0.61915 kka2_1:8_D216Y,kka2_1:8_216,Kka2,kka2_1:8,P00552,0.619185,NO,216,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.785,-4.248,3.463,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.100394,0.00229969,0.619185 kka2_1:8_D216Y,kka2_1:8_216,Kka2,kka2_1:8,P00552,0.619185,NO,216,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.785,-4.248,3.463,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.100394,0.00229969,0.619185 kka2_1:1_V16S,kka2_1:1_16,Kka2,kka2_1:1,P00552,0.61926,NO,16,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-3.087,-2.803,-0.284,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.520039,0.00694011,0.61926 beta-lactamase_625_Q88P,beta-lactamase_625_88,TEM-1,beta-lactamase_625,P62593,0.619405,NO,88,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.086,-3.948,1.862,,0.807,,B,0.64,2.03,1.84,,77.62,APH,-1.53433,0.213352,0.00504167,0.619405 beta-lactamase_2500_V106K,beta-lactamase_2500_106,TEM-1,beta-lactamase_2500,P62593,0.619485,NO,106,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.218,-3.831,2.613,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.361275,0.00304168,0.619485 kka2_1:2_W24A,kka2_1:2_24,Kka2,kka2_1:2,P00552,0.619647,NO,24,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-1.779,-3.385,1.606,,0.477,E,B,1.51,-0.21,2.666,,56.06,AHH,-2.24467,0.295029,0.00631564,0.619647 beta-lactamase_2500_R202I,beta-lactamase_2500_202,TEM-1,beta-lactamase_2500,P62593,0.61971,NO,202,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.292,-4.027,2.735,,0.188,H,A,1.2,0.62,3.734,,77.62,PBP,-1.54767,0.361275,0.00321899,0.61971 kka2_1:4_D261V,kka2_1:4_261,Kka2,kka2_1:4,P00552,0.619859,NO,261,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.708,-3.782,3.074,,0.146,G,A,0.75,-0.33,,,,HAA,-0.759333,0.168804,0.0224846,0.619859 beta-lactamase_2500_A123C,beta-lactamase_2500_123,TEM-1,beta-lactamase_2500,P62593,0.619911,NO,123,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.834,-4.461,3.627,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.361275,0.0010157,0.619911 kka2_1:8_F206S,kka2_1:8_206,Kka2,kka2_1:8,P00552,0.619917,NO,206,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.349,-3.736,2.387,,0.006,E,B,1.62,-1.21,1.052,,63.64,OHH,-1.04,0.100394,0.00936868,0.619917 kka2_1:8_F206S,kka2_1:8_206,Kka2,kka2_1:8,P00552,0.619917,NO,206,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.349,-3.736,2.387,,0.006,E,B,1.62,-1.21,1.052,,63.64,OHH,-1.04,0.100394,0.00936868,0.619917 kka2_1:1_Q27K,kka2_1:1_27,Kka2,kka2_1:1,P00552,0.620035,NO,27,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-1.659,-3.492,1.833,,0.608,.,A,0.64,0.71,0.521,,65.53,PPP,-1.90733,0.520039,0.00595365,0.620035 kka2_1:2_P45C,kka2_1:2_45,Kka2,kka2_1:2,P00552,0.620046,NO,45,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.774,-5.158,3.384,,0.669,,B,0.52,-0.76,4.882,,71.59,BOH,-2.152,0.295029,0.00590481,0.620046 kka2_1:2_R253C,kka2_1:2_253,Kka2,kka2_1:2,P00552,0.620047,NO,253,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.356,-3.227,1.871,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.295029,0.0144195,0.620047 beta-lactamase_2500_M67I,beta-lactamase_2500_67,TEM-1,beta-lactamase_2500,P62593,0.620119,NO,67,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-2.231,-2.93,0.699,,0.006,G,P,0.55,-0.81,2.653,,65.03,HHP,-1.502,0.361275,0.00409753,0.620119 Pab1_V198F,Pab1_198,Pab1,Pab1,P04147,0.620186,NO,198,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.113,-3.659,2.546,,0.008,E,B,0.61,0.91,,,,HHH,-1.32933,0.175299,0.000268557,0.620186 beta-lactamase_625_V117F,beta-lactamase_625_117,TEM-1,beta-lactamase_625,P62593,0.620204,NO,117,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.53,-3.756,2.226,,,H,A,0.44,-0.34,1.23,,65.03,PHB,-1.741,0.213352,0.00467906,0.620204 beta-lactamase_L197E,beta-lactamase_197,TEM-1,beta-lactamase,P62593,0.620251,NO,197,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.853,-3.853,3,5.19172,0.007,S,B,1.3,0.33,1.756,,60.14,HHP,-1.833,0.221079,0.00144602,0.620251 kka2_1:2_R122P,kka2_1:2_122,Kka2,kka2_1:2,P00552,0.620275,NO,122,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.175,-3.279,1.104,,0.487,H,A,1.2,0.26,16.436,16.436,71.59,BBH,-1.53833,0.295029,0.00736512,0.620275 beta-lactamase_2500_G253I,beta-lactamase_2500_253,TEM-1,beta-lactamase_2500,P62593,0.620325,NO,253,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.361275,0.00786358,0.620325 beta-lactamase_625_M67F,beta-lactamase_625_67,TEM-1,beta-lactamase_625,P62593,0.620343,NO,67,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-2.231,-4.128,1.897,,0.006,G,P,0.55,-0.81,2.653,,65.03,HHP,-1.502,0.213352,0.00409753,0.620343 kka2_1:1_Q163Y,kka2_1:1_163,Kka2,kka2_1:1,P00552,0.620373,NO,163,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.162,-4.27,2.108,,0.58,T,B,0.64,1.85,2.779,,64.02,BPO,-1.78333,0.520039,0.00719507,0.620373 beta-lactamase_D83K,beta-lactamase_83,TEM-1,beta-lactamase,P62593,0.620436,NO,83,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.066,-3.429,2.363,5.40616,0.354,H,A,1.33,0.22,0.861,,48.95,HAH,-1.34733,0.221079,0.00205968,0.620436 beta-lactamase_2500_T147I,beta-lactamase_2500_147,TEM-1,beta-lactamase_2500,P62593,0.620451,NO,147,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.149,-2.792,1.643,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.361275,0.00226017,0.620451 beta-lactamase_2500_G85T,beta-lactamase_2500_85,TEM-1,beta-lactamase_2500,P62593,0.620523,NO,85,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.011,-3.637,2.626,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.361275,0.00252173,0.620523 kka2_1:8_K50V,kka2_1:8_50,Kka2,kka2_1:8,P00552,0.620534,NO,50,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-0.833,-3.601,2.768,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.100394,0.00138626,0.620534 kka2_1:8_K50V,kka2_1:8_50,Kka2,kka2_1:8,P00552,0.620534,NO,50,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-0.833,-3.601,2.768,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.100394,0.00138626,0.620534 beta-lactamase_2500_L55W,beta-lactamase_2500_55,TEM-1,beta-lactamase_2500,P62593,0.620578,NO,55,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.86,-2.099,0.239,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.361275,0.00403741,0.620578 beta-lactamase_2500_R176E,beta-lactamase_2500_176,TEM-1,beta-lactamase_2500,P62593,0.620585,NO,176,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-0.863,-3.215,2.352,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.361275,0.00105554,0.620585 Pab1_F173C,Pab1_173,Pab1,Pab1,P04147,0.620657,NO,173,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.477,-4.751,3.274,,,E,B,0.87,-0.16,1.636,,63.26,BHA,-1.36967,0.175299,0.00148779,0.620657 beta-lactamase_625_S266L,beta-lactamase_625_266,TEM-1,beta-lactamase_625,P62593,0.620662,NO,266,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.213352,0.0140785,0.620662 kka2_1:2_D157T,kka2_1:2_157,Kka2,kka2_1:2,P00552,0.620775,NO,157,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.993,-3.488,2.495,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.295029,0.0042313,0.620775 beta-lactamase_625_G240A,beta-lactamase_625_240,TEM-1,beta-lactamase_625,P62593,0.62083,NO,240,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.213352,0.00591201,0.62083 kka2_1:2_A56N,kka2_1:2_56,Kka2,kka2_1:2,P00552,0.620913,NO,56,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.083,-3.917,1.834,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.295029,0.00717715,0.620913 Ubiquitin_A46F,Ubiquitin_46,Uba1,Ubiquitin,P0CG48,0.620968,NO,46,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.77,-4.16,2.39,5.38761,0.398,T,L,2.34,-0.8,6.506,,51.09,HHO,-1.505,0.205827,0.000581142,0.620968 Ubiquitin_A46R,Ubiquitin_46,Uba1,Ubiquitin,P0CG48,0.620968,NO,46,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.77,-3.031,1.261,5.38761,0.398,T,L,2.34,-0.8,6.506,,51.09,HHO,-1.505,0.205827,0.000581142,0.620968 Ubiquitin_D58H,Ubiquitin_58,Uba1,Ubiquitin,P0CG48,0.620968,NO,58,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.622,-4.497,2.875,5.06391,0.457,G,A,,-0.54,,,,PAH,-1.60267,0.205827,0.000639847,0.620968 Ubiquitin_E64K,Ubiquitin_64,Uba1,Ubiquitin,P0CG48,0.620968,NO,64,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.763,-2.849,1.086,5.084,0.54,T,l,,0.79,,,,BAP,-1.64433,0.205827,0.000817406,0.620968 Ubiquitin_L15H,Ubiquitin_15,Uba1,Ubiquitin,P0CG48,0.620968,NO,15,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.082,-4.931,3.849,5.14718,0.029,E,B,1.16,-0.53,0.936,,38.69,PHA,-1.40833,0.205827,0.000519738,0.620968 Ubiquitin_L67G,Ubiquitin_67,Uba1,Ubiquitin,P0CG48,0.620968,NO,67,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.435,-3.694,2.259,4.92156,,E,B,1.19,-1.02,6.371,6.371,30.8,PHB,-1.628,0.205827,0.000482727,0.620968 Ubiquitin_Q41F,Ubiquitin_41,Uba1,Ubiquitin,P0CG48,0.620968,NO,41,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-1.329,-4.131,2.802,4.9201,0.017,E,B,0.12,-0.98,0.812,,30.07,PPB,-1.55067,0.205827,0.000521668,0.620968 Ubiquitin_R72A,Ubiquitin_72,Uba1,Ubiquitin,P0CG48,0.620968,NO,72,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.034,-2.705,0.671,5.19484,0.077,,B,1.41,-0.1,9.638,9.638,42.77,HBH,-1.82733,0.205827,0.000768249,0.620968 Pab1_G193P,Pab1_193,Pab1,Pab1,P04147,0.621014,NO,193,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.414,-3.744,2.33,,,,,,,,,,POP,-1.55733,0.175299,0.0014922,0.621014 kka2_1:4_G205C,kka2_1:4_205,Kka2,kka2_1:4,P00552,0.621108,NO,205,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.596,-5.115,4.519,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.168804,0.00221855,0.621108 kka2_1:2_T225N,kka2_1:2_225,Kka2,kka2_1:2,P00552,0.621143,NO,225,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.393,-4.009,1.616,,0.036,H,A,0.22,-1.22,4.554,,63.64,HPB,-1.58733,0.295029,0.0113598,0.621143 kka2_1:1_I254S,kka2_1:1_254,Kka2,kka2_1:1,P00552,0.621156,NO,254,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.933,-3.691,1.758,,0.135,H,A,1.52,-0.6,1.859,,71.59,BHH,-1.668,0.520039,0.0132375,0.621156 beta-lactamase_2500_A222W,beta-lactamase_2500_222,TEM-1,beta-lactamase_2500,P62593,0.621235,NO,222,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.103,-5.409,3.306,,0.233,H,A,0.46,-0.25,0.379,,77.62,PHH,-1.63733,0.361275,0.00466094,0.621235 kka2_1:2_D134C,kka2_1:2_134,Kka2,kka2_1:2,P00552,0.621296,NO,134,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.969,-5.129,4.16,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.295029,0.00270812,0.621296 kka2_1:2_V198L,kka2_1:2_198,Kka2,kka2_1:2,P00552,0.621329,NO,198,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.719,-3.148,1.429,,0.05,E,B,1.48,-0.95,1.074,,56.06,HHA,-1.88667,0.295029,0.00835002,0.621329 beta-lactamase_0_K254W,beta-lactamase_0_254,TEM-1,beta-lactamase_0,P62593,0.621342,NO,254,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.0500837,0.00369,0.621342 beta-lactamase_L137G,beta-lactamase_137,TEM-1,beta-lactamase,P62593,0.62136,NO,137,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.03,-3.837,2.807,5.20117,,H,A,1.07,-0.38,0.674,,42.31,HHP,-1.58933,0.221079,0.00278599,0.62136 beta-lactamase_T158V,beta-lactamase_158,TEM-1,beta-lactamase,P62593,0.621368,NO,158,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.116,-3.299,2.183,5.32011,0.036,,B,0.98,-0.85,2.755,,69.58,HPB,-1.269,0.221079,0.00341825,0.621368 beta-lactamase_R63R,beta-lactamase_63,TEM-1,beta-lactamase,P62593,0.621456,NO,63,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-0.943,-0.943,,5.49979,0.218,,B,0.45,-0.31,0.677,,44.06,ABH,-0.992333,0.221079,0.00126938,0.621456 kka2_1:1_D159Y,kka2_1:1_159,Kka2,kka2_1:1,P00552,0.621532,NO,159,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.82,-4.45,3.63,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.520039,0.0030485,0.621532 beta-lactamase_2500_D48N,beta-lactamase_2500_48,TEM-1,beta-lactamase_2500,P62593,0.62158,NO,48,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.101,-3.389,2.288,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.361275,0.0027273,0.62158 kka2_1:2_F240Q,kka2_1:2_240,Kka2,kka2_1:2,P00552,0.621591,NO,240,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-0.911,-4.376,3.465,,,H,A,0.58,-1.21,0.373,,50.38,BHH,-1.67267,0.295029,0.00552543,0.621591 beta-lactamase_156_I244S,beta-lactamase_156_244,TEM-1,beta-lactamase_156,P62593,0.621603,NO,244,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.555,-3.602,2.047,,,E,B,0.48,-0.84,1.325,,77.62,OHH,-1.385,0.111618,0.00605379,0.621603 kka2_1:1_D227N,kka2_1:1_227,Kka2,kka2_1:1,P00552,0.621678,NO,227,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.758,-3.296,1.538,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.520039,0.00745029,0.621678 kka2_1:8_V185L,kka2_1:8_185,Kka2,kka2_1:8,P00552,0.621794,NO,185,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.045,-2.834,1.789,,0.058,E,B,1.48,-0.49,1.234,,46.97,HHH,-1.184,0.100394,0.00367031,0.621794 kka2_1:8_V185L,kka2_1:8_185,Kka2,kka2_1:8,P00552,0.621794,NO,185,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.045,-2.834,1.789,,0.058,E,B,1.48,-0.49,1.234,,46.97,HHH,-1.184,0.100394,0.00367031,0.621794 beta-lactamase_L167F,beta-lactamase_167,TEM-1,beta-lactamase,P62593,0.621802,NO,167,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.138,-3.813,2.675,5.13111,0.015,G,A,0.08,-0.63,0.4,,64.69,AHP,-1.30767,0.221079,0.00303566,0.621802 kka2_1:4_R226L,kka2_1:4_226,Kka2,kka2_1:4,P00552,0.621825,NO,226,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.392,-3.592,2.2,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.168804,0.0108032,0.621825 beta-lactamase_2500_A215E,beta-lactamase_2500_215,TEM-1,beta-lactamase_2500,P62593,0.621968,NO,215,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.503,-3.531,2.028,,,,a,0.46,-0.93,3.516,,74.48,HHO,-1.42633,0.361275,0.00544007,0.621968 kka2_1:1_E96G,kka2_1:1_96,Kka2,kka2_1:1,P00552,0.621974,NO,96,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.573,-2.57,-0.003,,0.476,,B,1.52,-0.65,1.254,,71.59,OAH,-2.143,0.520039,0.00369441,0.621974 beta-lactamase_0_P172I,beta-lactamase_0_172,TEM-1,beta-lactamase_0,P62593,0.622033,NO,172,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.998,-3.854,2.856,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.0500837,0.00312594,0.622033 kka2_1:2_D190Y,kka2_1:2_190,Kka2,kka2_1:2,P00552,0.622129,NO,190,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.708,-4.416,3.708,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.295029,0.00247989,0.622129 kka2_1:2_V97I,kka2_1:2_97,Kka2,kka2_1:2,P00552,0.62213,NO,97,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.453,-2.403,0.95,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.295029,0.00737869,0.62213 Pab1_K156N,Pab1_156,Pab1,Pab1,P04147,0.622155,NO,156,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.083,-3.265,2.182,,0.406,E,B,1.82,-0.26,,,,PBH,-1.58167,0.175299,0.000316767,0.622155 kka2_1:8_L92F,kka2_1:8_92,Kka2,kka2_1:8,P00552,0.622168,NO,92,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.893,-3.727,2.834,,0.007,E,B,1.59,-0.19,1.719,,63.26,HHH,-0.962,0.100394,0.00307177,0.622168 kka2_1:8_L92F,kka2_1:8_92,Kka2,kka2_1:8,P00552,0.622168,NO,92,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.893,-3.727,2.834,,0.007,E,B,1.59,-0.19,1.719,,63.26,HHH,-0.962,0.100394,0.00307177,0.622168 WW_domain_Q195Y,WW_domain_195,Yap65,WW_domain,P46937,0.622187,NO,195,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-1.839,-4.021,2.182,5.22735,,,,,,1.803,,70.04,APP,-1.719,0.153962,0.00394344,0.622187 beta-lactamase_2500_P165S,beta-lactamase_2500_165,TEM-1,beta-lactamase_2500,P62593,0.622246,NO,165,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.373,-3.19,1.817,,0.203,T,A,0.52,-0.31,0.414,,73.78,AOA,-1.359,0.361275,0.00549538,0.622246 kka2_1:4_V36C,kka2_1:4_36,Kka2,kka2_1:4,P00552,0.622299,NO,36,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-0.898,-4.71,3.812,,0.292,E,B,0.44,0.21,0.278,,52.27,HHH,-1.484,0.168804,0.00245633,0.622299 beta-lactamase_T131H,beta-lactamase_131,TEM-1,beta-lactamase,P62593,0.622345,NO,131,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.328,-4.721,3.393,5.0548,,H,A,0.53,-0.69,3.306,,67.48,PPH,-1.00867,0.221079,0.00345886,0.622345 kka2_1:2_A191V,kka2_1:2_191,Kka2,kka2_1:2,P00552,0.62238,NO,191,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.831,-3.195,2.364,,,.,b,0.46,-0.94,2.046,,50,AHO,-0.868667,0.295029,0.00338807,0.62238 beta-lactamase_625_I140N,beta-lactamase_625_140,TEM-1,beta-lactamase_625,P62593,0.622449,NO,140,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.733,-4.2,2.467,,0.128,H,A,0.48,0.41,1.628,,73.08,PHO,-1.48733,0.213352,0.00597777,0.622449 beta-lactamase_0_Q97C,beta-lactamase_0_97,TEM-1,beta-lactamase_0,P62593,0.622501,NO,97,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.072,-5.163,3.091,,0.823,G,A,0.64,2.42,16.954,16.954,77.62,PPP,-2.43833,0.0500837,0.0045116,0.622501 beta-lactamase_N152P,beta-lactamase_152,TEM-1,beta-lactamase,P62593,0.622503,NO,152,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-2.757,-3.97,1.213,5.98571,0.863,H,A,0.09,0.92,2.061,,77.62,BPH,-2.97,0.221079,0.00471429,0.622503 kka2_1:8_F171I,kka2_1:8_171,Kka2,kka2_1:8,P00552,0.622521,NO,171,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.326,-2.784,1.458,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.100394,0.00821426,0.622521 kka2_1:8_F171I,kka2_1:8_171,Kka2,kka2_1:8,P00552,0.622521,NO,171,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.326,-2.784,1.458,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.100394,0.00821426,0.622521 kka2_1:1_D62G,kka2_1:1_62,Kka2,kka2_1:1,P00552,0.62256,NO,62,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.591,-1.697,0.106,,0.262,H,A,0.75,0.08,10.048,10.048,64.39,PAA,-1.77833,0.520039,0.00744243,0.62256 kka2_1:8_E59V,kka2_1:8_59,Kka2,kka2_1:8,P00552,0.622625,NO,59,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-0.952,-3.591,2.639,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.100394,0.00280355,0.622625 kka2_1:8_E59V,kka2_1:8_59,Kka2,kka2_1:8,P00552,0.622625,NO,59,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-0.952,-3.591,2.639,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.100394,0.00280355,0.622625 beta-lactamase_625_R63W,beta-lactamase_625_63,TEM-1,beta-lactamase_625,P62593,0.622669,NO,63,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-0.943,-5.32,4.377,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.213352,0.00126938,0.622669 kka2_1:8_D101Y,kka2_1:8_101,Kka2,kka2_1:8,P00552,0.622677,NO,101,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.028,-4.399,3.371,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.100394,0.00423361,0.622677 kka2_1:8_D101Y,kka2_1:8_101,Kka2,kka2_1:8,P00552,0.622677,NO,101,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.028,-4.399,3.371,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.100394,0.00423361,0.622677 kka2_1:8_G210V,kka2_1:8_210,Kka2,kka2_1:8,P00552,0.622677,NO,210,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.095,-3.659,2.564,,0.103,T,A,0.75,-0.62,2.687,,50,OOB,-0.966667,0.100394,0.00598378,0.622677 kka2_1:8_G210V,kka2_1:8_210,Kka2,kka2_1:8,P00552,0.622677,NO,210,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.095,-3.659,2.564,,0.103,T,A,0.75,-0.62,2.687,,50,OOB,-0.966667,0.100394,0.00598378,0.622677 kka2_1:2_A78G,kka2_1:2_78,Kka2,kka2_1:2,P00552,0.622707,NO,78,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.744,-3.281,1.537,,0.078,.,B,0.46,-0.53,0.206,,56.06,OHH,-1.863,0.295029,0.00457299,0.622707 kka2_1:8_F48Q,kka2_1:8_48,Kka2,kka2_1:8,P00552,0.622781,NO,48,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.453,-4.352,2.899,,0.296,E,B,1.62,-0.99,14.194,14.194,55.3,HHH,-1.444,0.100394,0.00475422,0.622781 kka2_1:8_F48Q,kka2_1:8_48,Kka2,kka2_1:8,P00552,0.622781,NO,48,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.453,-4.352,2.899,,0.296,E,B,1.62,-0.99,14.194,14.194,55.3,HHH,-1.444,0.100394,0.00475422,0.622781 beta-lactamase_D155E,beta-lactamase_155,TEM-1,beta-lactamase,P62593,0.622789,NO,155,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.889,-2.299,1.41,4.92265,0.049,,B,0.45,-0.9,3.208,,64.69,OAB,-1.62267,0.221079,0.00135315,0.622789 kka2_1:1_M148V,kka2_1:1_148,Kka2,kka2_1:1,P00552,0.622815,NO,148,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.847,-1.708,-0.139,,0.268,H,A,1.59,0.71,4.618,,64.39,BHA,-1.65467,0.520039,0.00982664,0.622815 kka2_1:2_R145C,kka2_1:2_145,Kka2,kka2_1:2,P00552,0.622873,NO,145,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.804,-5.218,3.414,,0.346,H,A,1.2,1.23,7.961,,63.64,HBP,-1.88033,0.295029,0.00846663,0.622873 kka2_1:2_T72Y,kka2_1:2_72,Kka2,kka2_1:2,P00552,0.622902,NO,72,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.38,-4.457,2.077,,0.784,H,A,0.82,0.29,6.463,,65.53,HPP,-2.238,0.295029,0.00750756,0.622902 beta-lactamase_0_L89Q,beta-lactamase_0_89,TEM-1,beta-lactamase_0,P62593,0.62306,NO,89,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.096,-4.086,2.99,,0.168,T,A,0.55,0.63,2.373,,64.34,PHO,-1.75767,0.0500837,0.00207068,0.62306 beta-lactamase_625_D231K,beta-lactamase_625_231,TEM-1,beta-lactamase_625,P62593,0.62308,NO,231,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.816,-3.42,2.604,,,E,B,0.75,-1.06,1.025,,65.38,HAB,-0.994,0.213352,0.00107395,0.62308 beta-lactamase_L135R,beta-lactamase_135,TEM-1,beta-lactamase,P62593,0.623099,NO,135,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.002,-4.002,3,5.28497,0.117,H,A,1.07,-0.58,0.697,,43.71,PHH,-1.03767,0.221079,0.00244423,0.623099 beta-lactamase_0_D174V,beta-lactamase_0_174,TEM-1,beta-lactamase_0,P62593,0.623145,NO,174,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.738,-3.754,3.016,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.0500837,0.00125633,0.623145 kka2_1:2_E161K,kka2_1:2_161,Kka2,kka2_1:2,P00552,0.623166,NO,161,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.581,-3.478,1.897,,0.829,G,A,1.52,2.24,1.612,,92.05,AAB,-1.861,0.295029,0.00760103,0.623166 beta-lactamase_0_G39C,beta-lactamase_0_39,TEM-1,beta-lactamase_0,P62593,0.623198,NO,39,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.864,-5.191,3.327,,0.701,T,L,0.29,0.47,4.111,,77.62,HOH,-1.53633,0.0500837,0.00487611,0.623198 kka2_1:1_L152M,kka2_1:1_152,Kka2,kka2_1:1,P00552,0.623258,NO,152,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.521,-3.313,1.792,,0.547,.,A,0.55,1.36,1.589,,63.64,OHH,-1.162,0.520039,0.00674868,0.623258 kka2_1:1_A248V,kka2_1:1_248,Kka2,kka2_1:1,P00552,0.623451,NO,248,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.124,-2.592,0.468,,0.825,S,b,0.46,0.46,24.72,24.72,92.05,HHO,-2.15,0.520039,0.0125484,0.623451 kka2_1:2_G43V,kka2_1:2_43,Kka2,kka2_1:2,P00552,0.623461,NO,43,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.587,-3.838,2.251,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.295029,0.0071925,0.623461 beta-lactamase_2500_G142N,beta-lactamase_2500_142,TEM-1,beta-lactamase_2500,P62593,0.623521,NO,142,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.707,-3.445,2.738,,0.034,,p,0.29,-0.64,1.883,,64.69,OOO,-0.834,0.361275,0.00060149,0.623521 kka2_1:1_A237S,kka2_1:1_237,Kka2,kka2_1:1,P00552,0.623521,NO,237,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.12,-3.575,1.455,,0.068,H,A,0.46,-0.71,2.369,,92.05,HHA,-2.10433,0.520039,0.012257,0.623521 kka2_1:1_A166E,kka2_1:1_166,Kka2,kka2_1:1,P00552,0.623571,NO,166,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.407,-2.752,0.345,,0.534,.,B,0.46,1.03,1.147,,71.59,HHO,-2.421,0.520039,0.00799912,0.623571 beta-lactamase_0_L89N,beta-lactamase_0_89,TEM-1,beta-lactamase_0,P62593,0.62368,NO,89,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.096,-4.11,3.014,,0.168,T,A,0.55,0.63,2.373,,64.34,PHO,-1.75767,0.0500837,0.00207068,0.62368 Pab1_I137S,Pab1_137,Pab1,Pab1,P04147,0.623685,NO,137,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.212,-3.428,2.216,,0.068,,B,0.77,0.35,,,,AHA,-1.314,0.175299,0.000342224,0.623685 beta-lactamase_2500_T264L,beta-lactamase_2500_264,TEM-1,beta-lactamase_2500,P62593,0.623744,NO,264,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.361275,0.0119399,0.623744 kka2_1:2_M148T,kka2_1:2_148,Kka2,kka2_1:2,P00552,0.623747,NO,148,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.847,-2.724,0.877,,0.268,H,A,1.59,0.71,1.439,,64.39,BHA,-1.65467,0.295029,0.00982664,0.623747 beta-lactamase_2500_P224G,beta-lactamase_2500_224,TEM-1,beta-lactamase_2500,P62593,0.623788,NO,224,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.893,-3.351,2.458,,0.383,,B,0.52,-0.3,2.666,,74.48,HOH,-1.26433,0.361275,0.00189564,0.623788 beta-lactamase_0_V157E,beta-lactamase_0_157,TEM-1,beta-lactamase_0,P62593,0.623833,NO,157,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.751,-3.68,1.929,,0.308,S,a,0.44,-0.75,3.106,,69.58,BHP,-2.00767,0.0500837,0.00506849,0.623833 PSD95pdz3_D332P,PSD95pdz3_332,PSD95pdz3,PSD95pdz3,P31016,0.62387,NO,332,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.264,-3.336,2.072,6.09878,,,,,48.762,,,,AAO,-1.22533,0.0758425,0.000937818,0.62387 beta-lactamase_2500_R63M,beta-lactamase_2500_63,TEM-1,beta-lactamase_2500,P62593,0.623898,NO,63,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-0.943,-4.402,3.459,,0.218,,B,1.2,-0.31,0.929,,44.06,ABH,-0.992333,0.361275,0.00126938,0.623898 kka2_1:1_A14P,kka2_1:1_14,Kka2,kka2_1:1,P00552,0.623944,NO,14,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.837,-3.126,1.289,,0.728,G,A,0.46,0.7,1.17,,71.59,HHH,-1.82567,0.520039,0.00706614,0.623944 beta-lactamase_R59Y,beta-lactamase_59,TEM-1,beta-lactamase,P62593,0.623974,NO,59,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.345,-4.267,2.922,5.49837,0.329,S,L,0.68,-0.09,1.806,,73.08,HBO,-2.24267,0.221079,0.00318082,0.623974 beta-lactamase_0_E175H,beta-lactamase_0_175,TEM-1,beta-lactamase_0,P62593,0.624126,NO,175,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.336,-3.355,1.019,,0.551,,A,1.04,1.05,2.334,,77.62,AAB,-1.31233,0.0500837,0.00482205,0.624126 beta-lactamase_2500_P143Q,beta-lactamase_2500_143,TEM-1,beta-lactamase_2500,P62593,0.624161,NO,143,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.967,-4.024,3.057,,0.075,H,A,0.52,-0.37,0.479,,66.78,OOB,-1.354,0.361275,0.00114551,0.624161 Pab1_K140D,Pab1_140,Pab1,Pab1,P04147,0.624318,NO,140,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.083,-3.286,2.203,,0.345,H,A,,-0.73,,,,PBH,-1.20767,0.175299,0.000337366,0.624318 beta-lactamase_625_T116H,beta-lactamase_625_116,TEM-1,beta-lactamase_625,P62593,0.624529,NO,116,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.28,-4.615,3.335,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.213352,0.00336175,0.624529 kka2_1:2_L184F,kka2_1:2_184,Kka2,kka2_1:2,P00552,0.624543,NO,184,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.496,-2.947,1.451,,0.489,E,B,0.55,-0.06,14.044,14.044,63.26,AHH,-1.24833,0.295029,0.00518742,0.624543 beta-lactamase_G52V,beta-lactamase_52,TEM-1,beta-lactamase,P62593,0.624544,NO,52,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.149,-3.738,2.589,5.12093,0.299,,l,0.77,-0.04,2.103,,64.69,POB,-1.66267,0.221079,0.00340138,0.624544 gb1_N261T,gb1_261,gb1,gb1,P06654,0.624587,NO,261,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-1.863,-1.808,-0.055,,,,,,,1.191,,44.87,HPA,-2.16033,0.177985,0.0061875,0.624587 beta-lactamase_P105D,beta-lactamase_105,TEM-1,beta-lactamase,P62593,0.62466,NO,105,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.813,-3.466,2.653,5.08236,0.226,T,A,0.98,0.8,1.154,,63.29,POH,-1.01533,0.221079,0.0011981,0.62466 beta-lactamase_0_S241N,beta-lactamase_0_241,TEM-1,beta-lactamase_0,P62593,0.624676,NO,241,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.0500837,0.00452736,0.624676 kka2_1:2_R147K,kka2_1:2_147,Kka2,kka2_1:2,P00552,0.62484,NO,147,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.123,-3.064,1.941,,0.094,H,A,1.2,0.97,0.425,,64.02,PBH,-1.98267,0.295029,0.00549168,0.62484 beta-lactamase_D174H,beta-lactamase_174,TEM-1,beta-lactamase,P62593,0.624886,NO,174,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.738,-4.455,3.717,5.44133,0.238,,B,1.22,-0.1,,,,PAA,-1.91233,0.221079,0.00125633,0.624886 kka2_1:1_M116K,kka2_1:1_116,Kka2,kka2_1:1,P00552,0.624901,NO,116,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-2.482,-3.871,1.389,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.520039,0.00745147,0.624901 beta-lactamase_625_L74E,beta-lactamase_625_74,TEM-1,beta-lactamase_625,P62593,0.624906,NO,74,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.296,-3.786,2.49,,,H,A,0.55,-0.91,0.895,,50,HHO,-1.34933,0.213352,0.00493255,0.624906 beta-lactamase_A211P,beta-lactamase_211,TEM-1,beta-lactamase,P62593,0.624948,NO,211,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.896,-3.94,2.044,5.54662,0.369,T,A,0.52,-0.69,2.061,,77.62,AHA,-1.94633,0.221079,0.00648183,0.624948 kka2_1:8_I228R,kka2_1:8_228,Kka2,kka2_1:8,P00552,0.625002,NO,228,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.142,-4.209,3.067,,,H,A,1.52,-1.2,1.521,,71.59,AHH,-1.54633,0.100394,0.00458834,0.625002 kka2_1:8_I228R,kka2_1:8_228,Kka2,kka2_1:8,P00552,0.625002,NO,228,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.142,-4.209,3.067,,,H,A,1.52,-1.2,1.521,,71.59,AHH,-1.54633,0.100394,0.00458834,0.625002 kka2_1:2_L39P,kka2_1:2_39,Kka2,kka2_1:2,P00552,0.625047,NO,39,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.223,-4.188,2.965,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.295029,0.00493618,0.625047 Pab1_F146H,Pab1_146,Pab1,Pab1,P04147,0.62505,NO,146,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.149,-4.272,3.123,,0.006,H,A,,0.75,,,,PHP,-1.161,0.175299,0.000329265,0.62505 beta-lactamase_625_I285E,beta-lactamase_625_285,TEM-1,beta-lactamase_625,P62593,0.625094,NO,285,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.213352,0.101555,0.625094 kka2_1:4_L93P,kka2_1:4_93,Kka2,kka2_1:4,P00552,0.625132,NO,93,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.815,-4.131,3.316,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.168804,0.00131498,0.625132 beta-lactamase_0_M115T,beta-lactamase_0_115,TEM-1,beta-lactamase_0,P62593,0.6252,NO,115,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.389,-3.522,2.133,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.0500837,0.0034337,0.6252 beta-lactamase_I243T,beta-lactamase_243,TEM-1,beta-lactamase,P62593,0.625637,NO,243,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.532,-3.497,1.965,5.26886,,E,B,1.68,-1.24,2.289,,50,OHH,-1.46867,0.221079,0.00464034,0.625637 kka2_1:1_R140L,kka2_1:1_140,Kka2,kka2_1:1,P00552,0.625653,NO,140,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.351,-3.517,2.166,,0.12,H,A,1.2,0.2,11.345,11.345,53.03,BBH,-1.885,0.520039,0.00430167,0.625653 beta-lactamase_L79C,beta-lactamase_79,TEM-1,beta-lactamase,P62593,0.625698,NO,79,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.842,-4.663,3.821,4.98681,0.007,H,A,1.07,-0.16,0.823,,50.35,HHP,-1.44333,0.221079,0.000947397,0.625698 beta-lactamase_N134R,beta-lactamase_134,TEM-1,beta-lactamase,P62593,0.625732,NO,134,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-0.879,-3.446,2.567,5.07245,0.138,H,A,0.09,-0.6,1.441,,53.15,HPH,-1.02233,0.221079,0.000644786,0.625732 beta-lactamase_39_I280Y,beta-lactamase_39_280,TEM-1,beta-lactamase_39,P62593,0.625736,NO,280,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.0495842,0.0530888,0.625736 beta-lactamase_625_P165W,beta-lactamase_625_165,TEM-1,beta-lactamase_625,P62593,0.625818,NO,165,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.373,-5.352,3.979,,0.203,T,A,0.52,-0.31,0.414,,73.78,AOA,-1.359,0.213352,0.00549538,0.625818 beta-lactamase_39_Y44Q,beta-lactamase_39_44,TEM-1,beta-lactamase_39,P62593,0.62587,NO,44,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-2.547,-4.196,1.649,,,E,B,0.21,-0.45,2.683,,73.78,OHH,-1.86267,0.0495842,0.00426364,0.62587 beta-lactamase_2500_L28S,beta-lactamase_2500_28,TEM-1,beta-lactamase_2500,P62593,0.625885,NO,28,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.579,-3.523,1.944,,0.277,H,A,0.55,-0.16,2.716,,93.01,PHH,-2.11333,0.361275,0.00359321,0.625885 beta-lactamase_2500_L38H,beta-lactamase_2500_38,TEM-1,beta-lactamase_2500,P62593,0.625937,NO,38,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.343,-3.182,1.839,,0.088,H,A,0.55,0.2,2.71,,64.34,PHO,-1.78033,0.361275,0.00373244,0.625937 PSD95pdz3_V328G,PSD95pdz3_328,PSD95pdz3,PSD95pdz3,P31016,0.62602,NO,328,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.465,-3.265,1.8,5.28275,,,,,16.8775,,,,HHO,-1.36767,0.0758425,0.000986706,0.62602 beta-lactamase_R241H,beta-lactamase_241,TEM-1,beta-lactamase,P62593,0.626051,NO,241,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.433,-4.46,3.027,5.02621,0.094,E,B,0.68,-0.16,1.327,,50,PBO,-1.42967,0.221079,0.00452736,0.626051 kka2_1:2_S68F,kka2_1:2_68,Kka2,kka2_1:2,P00552,0.626074,NO,68,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.623,-4.425,1.802,,0.48,H,A,0.27,-0.1,2.655,,71.59,HPH,-1.40767,0.295029,0.00608265,0.626074 WW_domain_S183C,WW_domain_183,Yap65,WW_domain,P46937,0.626084,NO,183,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.95,-4.76,2.81,5.35576,,,,,,1.594,,83.93,PPP,-1.48733,0.153962,0.00445513,0.626084 beta-lactamase_2500_I245T,beta-lactamase_2500_245,TEM-1,beta-lactamase_2500,P62593,0.6261,NO,245,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.361275,0.00391032,0.6261 kka2_1:1_E17K,kka2_1:1_17,Kka2,kka2_1:1,P00552,0.626144,NO,17,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.154,-2.831,0.677,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.520039,0.00688738,0.626144 beta-lactamase_L192H,beta-lactamase_192,TEM-1,beta-lactamase,P62593,0.626146,NO,192,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.254,-4.926,3.672,5.68899,0.095,H,A,1.3,0.35,1.756,,60.14,HHP,-1.41833,0.221079,0.00558728,0.626146 beta-lactamase_0_L146Y,beta-lactamase_0_146,TEM-1,beta-lactamase_0,P62593,0.626163,NO,146,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.462,-3.821,2.359,,0.007,H,A,0.55,-0.56,2.051,,64.69,AHP,-1.656,0.0500837,0.00474542,0.626163 beta-lactamase_H285I,beta-lactamase_285,TEM-1,beta-lactamase,P62593,0.626235,NO,285,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-1.845,-3.788,1.943,5.64289,0.312,T,a,0.35,0.64,1.401,,72.73,BBH,-1.64567,0.221079,0.101555,0.626235 beta-lactamase_D231I,beta-lactamase_231,TEM-1,beta-lactamase,P62593,0.626404,NO,231,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.816,-4.036,3.22,5.06651,,E,B,1.22,-1.06,0.319,,65.38,HAB,-0.994,0.221079,0.00107395,0.626404 beta-lactamase_I125A,beta-lactamase_125,TEM-1,beta-lactamase,P62593,0.626413,NO,125,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.441,-3.138,1.697,5.23481,,H,A,2.82,-0.7,2.301,,63.29,HHP,-1.248,0.221079,0.00383964,0.626413 kka2_1:8_V153S,kka2_1:8_153,Kka2,kka2_1:8,P00552,0.626594,NO,153,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.092,-3.643,2.551,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.100394,0.00501119,0.626594 kka2_1:8_V153S,kka2_1:8_153,Kka2,kka2_1:8,P00552,0.626594,NO,153,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.092,-3.643,2.551,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.100394,0.00501119,0.626594 kka2_1:2_S104L,kka2_1:2_104,Kka2,kka2_1:2,P00552,0.626721,NO,104,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.436,-3.504,2.068,,0.536,T,A,0.27,-1.11,5.49,,63.64,HPP,-1.91433,0.295029,0.00555207,0.626721 kka2_1:2_P98L,kka2_1:2_98,Kka2,kka2_1:2,P00552,0.626814,NO,98,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.526,-3.014,1.488,,0.391,S,B,0.52,-0.65,2.82,,63.26,HOO,-1.19167,0.295029,0.00622754,0.626814 kka2_1:4_L92Q,kka2_1:4_92,Kka2,kka2_1:4,P00552,0.626832,NO,92,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.893,-4.159,3.266,,0.007,E,B,0.55,-0.19,1.447,,63.26,HHH,-0.962,0.168804,0.00307177,0.626832 kka2_1:4_L184C,kka2_1:4_184,Kka2,kka2_1:4,P00552,0.62684,NO,184,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.496,-5.02,3.524,,0.489,E,B,1.59,-0.06,4.495,,63.26,AHH,-1.24833,0.168804,0.00518742,0.62684 kka2_1:8_A117T,kka2_1:8_117,Kka2,kka2_1:8,P00552,0.62685,NO,117,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.828,-3.259,2.431,,,H,A,1.04,-0.78,0.755,,45.83,HHA,-1.79333,0.100394,0.00282984,0.62685 kka2_1:8_A117T,kka2_1:8_117,Kka2,kka2_1:8,P00552,0.62685,NO,117,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.828,-3.259,2.431,,,H,A,1.04,-0.78,0.755,,45.83,HHA,-1.79333,0.100394,0.00282984,0.62685 Pab1_F168S,Pab1_168,Pab1,Pab1,P04147,0.626901,NO,168,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.269,-3.481,2.212,,,,,,,0.789,,56.33,OHO,-1.10033,0.175299,0.00064061,0.626901 beta-lactamase_0_T107K,beta-lactamase_0_107,TEM-1,beta-lactamase_0,P62593,0.626964,NO,107,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.117,-3.447,2.33,,,G,A,0.22,-0.06,3.73,,67.83,HPA,-1.265,0.0500837,0.00239347,0.626964 kka2_1:1_G99V,kka2_1:1_99,Kka2,kka2_1:1,P00552,0.626974,NO,99,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.596,-3.782,3.186,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.520039,0.00186055,0.626974 kka2_1:8_A78V,kka2_1:8_78,Kka2,kka2_1:8,P00552,0.627004,NO,78,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.744,-3.452,1.708,,0.078,,B,1.04,-0.53,1.251,,56.06,OHH,-1.863,0.100394,0.00457299,0.627004 kka2_1:8_A78V,kka2_1:8_78,Kka2,kka2_1:8,P00552,0.627004,NO,78,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.744,-3.452,1.708,,0.078,,B,1.04,-0.53,1.251,,56.06,OHH,-1.863,0.100394,0.00457299,0.627004 beta-lactamase_0_P224Y,beta-lactamase_0_224,TEM-1,beta-lactamase_0,P62593,0.627024,NO,224,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.893,-4.387,3.494,,0.383,,B,0.52,-0.3,3.587,,74.48,HOH,-1.26433,0.0500837,0.00189564,0.627024 beta-lactamase_625_R159G,beta-lactamase_625_159,TEM-1,beta-lactamase_625,P62593,0.62707,NO,159,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-0.94,-3.384,2.444,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.213352,0.00108472,0.62707 kka2_1:4_D33Y,kka2_1:4_33,Kka2,kka2_1:4,P00552,0.627084,NO,33,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.186,-4.503,2.317,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.168804,0.00633568,0.627084 beta-lactamase_2500_A235T,beta-lactamase_2500_235,TEM-1,beta-lactamase_2500,P62593,0.627193,NO,235,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.266,-2.412,1.146,,0.32,E,B,0.46,-0.86,0.891,,50,OHO,-0.89,0.361275,0.00493474,0.627193 kka2_1:2_R202G,kka2_1:2_202,Kka2,kka2_1:2,P00552,0.627204,NO,202,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.761,-2.403,0.642,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.295029,0.00696498,0.627204 beta-lactamase_0_L47N,beta-lactamase_0_47,TEM-1,beta-lactamase_0,P62593,0.627222,NO,47,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.876,-3.972,2.096,,0.007,E,B,0.55,0.2,1.024,,67.83,AHA,-1.639,0.0500837,0.00439844,0.627222 beta-lactamase_39_A246N,beta-lactamase_39_246,TEM-1,beta-lactamase_39,P62593,0.627263,NO,246,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.121,-4.23,2.109,,0.01,E,B,0.46,-1.01,1.331,,73.78,HHH,-1.55633,0.0495842,0.00569458,0.627263 kka2_1:8_R217M,kka2_1:8_217,Kka2,kka2_1:8,P00552,0.627464,NO,217,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.158,-4.484,3.326,,0.252,T,A,0.16,-0.59,1.151,,52.27,ABH,-1.127,0.100394,0.0047191,0.627464 kka2_1:8_R217M,kka2_1:8_217,Kka2,kka2_1:8,P00552,0.627464,NO,217,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.158,-4.484,3.326,,0.252,T,A,0.16,-0.59,1.151,,52.27,ABH,-1.127,0.100394,0.0047191,0.627464 kka2_1:8_M148D,kka2_1:8_148,Kka2,kka2_1:8,P00552,0.627505,NO,148,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.847,-4.109,2.262,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.100394,0.00982664,0.627505 kka2_1:8_M148D,kka2_1:8_148,Kka2,kka2_1:8,P00552,0.627505,NO,148,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.847,-4.109,2.262,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.100394,0.00982664,0.627505 kka2_1:1_A64C,kka2_1:1_64,Kka2,kka2_1:1,P00552,0.62752,NO,64,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.496,-4.794,3.298,,0.039,H,A,0.46,-0.57,1.175,,56.06,AHH,-1.334,0.520039,0.00705578,0.62752 kka2_1:2_H188L,kka2_1:2_188,Kka2,kka2_1:2,P00552,0.62752,NO,188,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-0.913,-3.61,2.697,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.295029,0.00273139,0.62752 beta-lactamase_156_V31W,beta-lactamase_156_31,TEM-1,beta-lactamase_156,P62593,0.627617,NO,31,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.822,-5.287,3.465,,,H,A,0.44,-0.46,4.126,,73.78,BHB,-2.03767,0.111618,0.00478065,0.627617 kka2_1:1_L152I,kka2_1:1_152,Kka2,kka2_1:1,P00552,0.627687,NO,152,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.521,-2.522,1.001,,0.547,.,A,0.55,1.36,1.589,,63.64,OHH,-1.162,0.520039,0.00674868,0.627687 beta-lactamase_2500_E195F,beta-lactamase_2500_195,TEM-1,beta-lactamase_2500,P62593,0.627735,NO,195,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.186,-4.475,2.289,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.361275,0.00496565,0.627735 kka2_1:1_D227Y,kka2_1:1_227,Kka2,kka2_1:1,P00552,0.627769,NO,227,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.758,-4.295,2.537,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.520039,0.00745029,0.627769 gb1_N263Y,gb1_263,gb1,gb1,P06654,0.627871,NO,263,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-1.162,-3.939,2.777,,,,,,,,,,APO,-2.04233,0.177985,0.0035297,0.627871 kka2_1:1_D227Q,kka2_1:1_227,Kka2,kka2_1:1,P00552,0.627921,NO,227,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.758,-3.747,1.989,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.520039,0.00745029,0.627921 kka2_1:2_E59K,kka2_1:2_59,Kka2,kka2_1:2,P00552,0.628054,NO,59,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-0.952,-3.163,2.211,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.295029,0.00280355,0.628054 kka2_1:1_L93V,kka2_1:1_93,Kka2,kka2_1:1,P00552,0.628143,NO,93,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.815,-2.967,2.152,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.520039,0.00131498,0.628143 kka2_1:8_I207A,kka2_1:8_207,Kka2,kka2_1:8,P00552,0.628258,NO,207,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.175,-3.122,1.947,,0.293,,B,1.52,-1.12,1.306,,56.06,HHA,-1.07733,0.100394,0.00611824,0.628258 kka2_1:8_I207A,kka2_1:8_207,Kka2,kka2_1:8,P00552,0.628258,NO,207,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.175,-3.122,1.947,,0.293,,B,1.52,-1.12,1.306,,56.06,HHA,-1.07733,0.100394,0.00611824,0.628258 kka2_1:2_A215G,kka2_1:2_215,Kka2,kka2_1:2,P00552,0.628299,NO,215,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.968,-3.05,2.082,,0.039,E,B,0.46,-0.59,2.137,,50.38,HHA,-1.00467,0.295029,0.00529129,0.628299 beta-lactamase_625_R59C,beta-lactamase_625_59,TEM-1,beta-lactamase_625,P62593,0.628323,NO,59,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.345,-2.854,1.509,,0.329,S,L,1.2,-0.09,2.995,,73.08,HBO,-2.24267,0.213352,0.00318082,0.628323 kka2_1:2_D134V,kka2_1:2_134,Kka2,kka2_1:2,P00552,0.628323,NO,134,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.969,-3.724,2.755,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.295029,0.00270812,0.628323 beta-lactamase_156_R257F,beta-lactamase_156_257,TEM-1,beta-lactamase_156,P62593,0.628334,NO,257,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.111618,0.00756629,0.628334 beta-lactamase_0_E56C,beta-lactamase_0_56,TEM-1,beta-lactamase_0,P62593,0.628353,NO,56,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.043,-4.827,2.784,,0.198,E,B,1.04,0.31,1.491,,72.73,HAP,-1.94033,0.0500837,0.00238534,0.628353 PSD95pdz3_V328W,PSD95pdz3_328,PSD95pdz3,PSD95pdz3,P31016,0.628394,NO,328,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.465,-5.004,3.539,5.28275,,,,,16.8775,,,,HHO,-1.36767,0.0758425,0.000986706,0.628394 kka2_1:1_T51S,kka2_1:1_51,Kka2,kka2_1:1,P00552,0.628401,NO,51,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.199,-2.009,-0.19,,0.05,E,B,0.22,-0.05,3.056,,63.64,BPA,-1.76767,0.520039,0.00628861,0.628401 kka2_1:2_D134I,kka2_1:2_134,Kka2,kka2_1:2,P00552,0.628404,NO,134,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.969,-3.956,2.987,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.295029,0.00270812,0.628404 kka2_1:2_V153A,kka2_1:2_153,Kka2,kka2_1:2,P00552,0.628419,NO,153,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.092,-2.452,1.36,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.295029,0.00501119,0.628419 beta-lactamase_625_I261A,beta-lactamase_625_261,TEM-1,beta-lactamase_625,P62593,0.628445,NO,261,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.213352,0.0123091,0.628445 kka2_1:8_L259P,kka2_1:8_259,Kka2,kka2_1:8,P00552,0.628586,NO,259,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.088,-4.066,2.978,,0.036,H,A,1.59,-0.15,1.83,,48.48,BHH,-1.15167,0.100394,0.0206964,0.628586 kka2_1:8_L259P,kka2_1:8_259,Kka2,kka2_1:8,P00552,0.628586,NO,259,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.088,-4.066,2.978,,0.036,H,A,1.59,-0.15,1.83,,48.48,BHH,-1.15167,0.100394,0.0206964,0.628586 beta-lactamase_N134S,beta-lactamase_134,TEM-1,beta-lactamase,P62593,0.628686,NO,134,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-0.879,-2.985,2.106,5.07245,0.138,H,A,0.09,-0.6,1.441,,53.15,HPH,-1.02233,0.221079,0.000644786,0.628686 beta-lactamase_39_R257W,beta-lactamase_39_257,TEM-1,beta-lactamase_39,P62593,0.628688,NO,257,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.0495842,0.00756629,0.628688 kka2_1:2_A222C,kka2_1:2_222,Kka2,kka2_1:2,P00552,0.628704,NO,222,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.725,-4.44,3.715,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.295029,0.00207657,0.628704 beta-lactamase_0_I171D,beta-lactamase_0_171,TEM-1,beta-lactamase_0,P62593,0.628711,NO,171,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-2.431,-3.888,1.457,,0.361,,B,0.48,0.53,16.954,16.954,77.62,HHO,-1.55533,0.0500837,0.00623355,0.628711 kka2_1:2_L126P,kka2_1:2_126,Kka2,kka2_1:2,P00552,0.628818,NO,126,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.246,-4.15,2.904,,0.285,S,B,0.55,0.12,1.392,,51.89,PHA,-1.744,0.295029,0.0066485,0.628818 beta-lactamase_625_G141I,beta-lactamase_625_141,TEM-1,beta-lactamase_625,P62593,0.628835,NO,141,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.828,-4.236,3.408,,0.575,T,l,0.29,-0.28,0.198,,64.69,HOO,-1.08933,0.213352,0.0012419,0.628835 kka2_1:2_D183Q,kka2_1:2_183,Kka2,kka2_1:2,P00552,0.628867,NO,183,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.204,-2.915,1.711,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.295029,0.00426304,0.628867 kka2_1:1_V153I,kka2_1:1_153,Kka2,kka2_1:1,P00552,0.628913,NO,153,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.092,-1.693,0.601,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.520039,0.00501119,0.628913 kka2_1:1_D134Y,kka2_1:1_134,Kka2,kka2_1:1,P00552,0.628916,NO,134,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.969,-4.401,3.432,,0.421,B,B,0.75,0.31,2.329,,49.62,HAB,-1.057,0.520039,0.00270812,0.628916 kka2_1:8_S32I,kka2_1:8_32,Kka2,kka2_1:8,P00552,0.628942,NO,32,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-0.804,-3.814,3.01,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.100394,0.00149998,0.628942 kka2_1:8_S32I,kka2_1:8_32,Kka2,kka2_1:8,P00552,0.628942,NO,32,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-0.804,-3.814,3.01,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.100394,0.00149998,0.628942 kka2_1:4_G210V,kka2_1:4_210,Kka2,kka2_1:4,P00552,0.62898,NO,210,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.095,-3.659,2.564,,0.103,T,A,0.29,-0.62,0.271,,50,OOB,-0.966667,0.168804,0.00598378,0.62898 kka2_1:1_V198C,kka2_1:1_198,Kka2,kka2_1:1,P00552,0.62901,NO,198,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.719,-4.752,3.033,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.520039,0.00835002,0.62901 Ubiquitin_A46Q,Ubiquitin_46,Uba1,Ubiquitin,P0CG48,0.629032,NO,46,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.77,-3.999,2.229,5.38761,0.398,T,L,2.34,-0.8,6.506,,51.09,HHO,-1.505,0.205827,0.000581142,0.629032 Ubiquitin_K11P,Ubiquitin_11,Uba1,Ubiquitin,P0CG48,0.629032,NO,11,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.354,-3.81,2.456,5.16813,0.401,,B,2.81,0.84,0.335,,25.84,OBP,-1.346,0.205827,0.000535553,0.629032 Ubiquitin_R72K,Ubiquitin_72,Uba1,Ubiquitin,P0CG48,0.629032,NO,72,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.034,-2.856,0.822,5.19484,0.077,,B,1.41,-0.1,9.638,9.638,42.77,HBH,-1.82733,0.205827,0.000768249,0.629032 Ubiquitin_R72Q,Ubiquitin_72,Uba1,Ubiquitin,P0CG48,0.629032,NO,72,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.034,-3.116,1.082,5.19484,0.077,,B,1.41,-0.1,9.638,9.638,42.77,HBH,-1.82733,0.205827,0.000768249,0.629032 Ubiquitin_T7M,Ubiquitin_7,Uba1,Ubiquitin,P0CG48,0.629032,NO,7,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.415,-3.034,1.619,4.954,0.094,E,B,0.43,-0.78,0.805,,21.31,BPH,-1.41033,0.205827,0.000647855,0.629032 Ubiquitin_T9R,Ubiquitin_9,Uba1,Ubiquitin,P0CG48,0.629032,NO,9,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.409,-3.791,2.382,5.24336,0.777,T,A,2.12,-0.12,2.705,,29.93,HPO,-1.50933,0.205827,0.000630716,0.629032 kka2_1:1_V36L,kka2_1:1_36,Kka2,kka2_1:1,P00552,0.629058,NO,36,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-0.898,-2.711,1.813,,0.292,E,B,0.44,0.21,0.278,,52.27,HHH,-1.484,0.520039,0.00245633,0.629058 kka2_1:1_R121Q,kka2_1:1_121,Kka2,kka2_1:1,P00552,0.629122,NO,121,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.552,-2.59,1.038,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.520039,0.00523326,0.629122 beta-lactamase_A123Y,beta-lactamase_123,TEM-1,beta-lactamase,P62593,0.629187,NO,123,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.834,-4.16,3.326,4.70061,0.039,H,A,0.52,-0.72,0.705,,41.26,PHH,-1.47367,0.221079,0.0010157,0.629187 beta-lactamase_V258S,beta-lactamase_258,TEM-1,beta-lactamase,P62593,0.629187,NO,258,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.975,-2.326,0.351,5.16083,,E,B,1.64,-1.02,2.124,,67.83,HHH,-1.67667,0.221079,0.007931,0.629187 kka2_1:4_I221M,kka2_1:4_221,Kka2,kka2_1:4,P00552,0.629197,NO,221,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.739,-4.064,2.325,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.168804,0.00945908,0.629197 beta-lactamase_625_L137E,beta-lactamase_625_137,TEM-1,beta-lactamase_625,P62593,0.629214,NO,137,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.03,-3.919,2.889,,,H,A,0.55,-0.38,1.5,,42.31,HHP,-1.58933,0.213352,0.00278599,0.629214 beta-lactamase_L120T,beta-lactamase_120,TEM-1,beta-lactamase,P62593,0.629268,NO,120,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.044,-3.547,2.503,5.11974,,H,A,1.3,-1.13,1.988,,64.69,AHO,-1.13633,0.221079,0.00143563,0.629268 kka2_1:2_I246S,kka2_1:2_246,Kka2,kka2_1:2,P00552,0.629345,NO,246,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-2.008,-3.645,1.637,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.295029,0.0139479,0.629345 kka2_1:8_A224E,kka2_1:8_224,Kka2,kka2_1:8,P00552,0.629349,NO,224,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.977,-3.569,2.592,,,H,A,0.46,-1.26,0.357,,63.64,HHP,-1.41033,0.100394,0.00352047,0.629349 kka2_1:8_A224E,kka2_1:8_224,Kka2,kka2_1:8,P00552,0.629349,NO,224,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.977,-3.569,2.592,,,H,A,0.46,-1.26,0.357,,63.64,HHP,-1.41033,0.100394,0.00352047,0.629349 kka2_1:4_K50Q,kka2_1:4_50,Kka2,kka2_1:4,P00552,0.629485,NO,50,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-0.833,-3.501,2.668,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.168804,0.00138626,0.629485 gb1_K254H,gb1_254,gb1,gb1,P06654,0.629488,NO,254,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.748,-4.174,2.426,,,,,,,1.793,,37.28,ABH,-2.195,0.177985,0.00622711,0.629488 kka2_1:8_D250W,kka2_1:8_250,Kka2,kka2_1:8,P00552,0.629603,NO,250,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.015,-5.585,4.57,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.100394,0.0177103,0.629603 kka2_1:8_D250W,kka2_1:8_250,Kka2,kka2_1:8,P00552,0.629603,NO,250,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.015,-5.585,4.57,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.100394,0.0177103,0.629603 PSD95pdz3_V386W,PSD95pdz3_386,PSD95pdz3,PSD95pdz3,P31016,0.629646,NO,386,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.465,-5.004,3.539,5.18836,,,,,17.5429,,,,PHP,-1.463,0.0758425,0.000184509,0.629646 kka2_1:1_L232V,kka2_1:1_232,Kka2,kka2_1:1,P00552,0.629685,NO,232,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.514,-2.443,0.929,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.520039,0.00800103,0.629685 kka2_1:4_S204H,kka2_1:4_204,Kka2,kka2_1:4,P00552,0.629733,NO,204,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.353,-4.723,3.37,,0.144,E,A,0.27,-1.2,2.442,,65.53,HPO,-0.953333,0.168804,0.00881794,0.629733 beta-lactamase_I93A,beta-lactamase_93,TEM-1,beta-lactamase,P62593,0.629747,NO,93,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.401,-3.13,1.729,5.74695,0.128,E,B,0.77,0.44,1.757,,67.83,BHB,-1.873,0.221079,0.00527066,0.629747 beta-lactamase_R255A,beta-lactamase_255,TEM-1,beta-lactamase,P62593,0.629751,NO,255,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.266,-2.711,0.445,5.55882,0.141,E,B,0.68,0.38,1.199,,63.99,PBH,-2.00433,0.221079,0.00499612,0.629751 kka2_1:1_S251V,kka2_1:1_251,Kka2,kka2_1:1,P00552,0.629828,NO,251,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.636,-3.716,1.08,,0.712,H,A,0.27,-0.25,1.356,,71.59,APP,-2.09367,0.520039,0.0138916,0.629828 kka2_1:2_H135R,kka2_1:2_135,Kka2,kka2_1:2,P00552,0.629999,NO,135,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-1.331,-2.597,1.266,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.295029,0.00532566,0.629999 kka2_1:4_D250F,kka2_1:4_250,Kka2,kka2_1:4,P00552,0.630076,NO,250,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.015,-4.403,3.388,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.168804,0.0177103,0.630076 beta-lactamase_0_D48M,beta-lactamase_0_48,TEM-1,beta-lactamase_0,P62593,0.630178,NO,48,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.101,-4.896,3.795,,0.189,E,B,0.75,0.21,17.825,17.825,50.35,HAH,-1.62467,0.0500837,0.0027273,0.630178 WW_domain_I193P,WW_domain_193,Yap65,WW_domain,P46937,0.630193,NO,193,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.993,-3.954,1.961,6.15906,,,,,,1.833,,83.33,BHA,-1.756,0.153962,0.00587613,0.630193 Pab1_S154R,Pab1_154,Pab1,Pab1,P04147,0.630198,NO,154,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.146,-3.525,2.379,,0.208,E,B,0.1,-0.75,,,,HPP,-1.408,0.175299,0.000319331,0.630198 kka2_1:1_D101Y,kka2_1:1_101,Kka2,kka2_1:1,P00552,0.63026,NO,101,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.028,-4.399,3.371,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.520039,0.00423361,0.63026 kka2_1:8_H188Y,kka2_1:8_188,Kka2,kka2_1:8,P00552,0.630313,NO,188,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-0.913,-3.365,2.452,,0.006,,A,0.87,-1.02,1.241,,47.73,PBO,-0.927333,0.100394,0.00273139,0.630313 kka2_1:8_H188Y,kka2_1:8_188,Kka2,kka2_1:8,P00552,0.630313,NO,188,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-0.913,-3.365,2.452,,0.006,,A,0.87,-1.02,1.241,,47.73,PBO,-0.927333,0.100394,0.00273139,0.630313 kka2_1:1_T85I,kka2_1:1_85,Kka2,kka2_1:1,P00552,0.630318,NO,85,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.165,-2.979,0.814,,0.576,E,B,0.82,1.39,16.653,16.653,71.59,HPA,-2.10133,0.520039,0.00634493,0.630318 beta-lactamase_0_A40C,beta-lactamase_0_40,TEM-1,beta-lactamase_0,P62593,0.630335,NO,40,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.402,-4.779,3.377,,0.155,S,B,0.46,0.21,0.783,,73.78,OHB,-1.40267,0.0500837,0.00490026,0.630335 beta-lactamase_W286H,beta-lactamase_286,TEM-1,beta-lactamase,P62593,0.630351,NO,286,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-1.111,-4.497,3.386,6.64456,0.492,,?,0.01,0.6,,,,BHX,-1.478,0.221079,,0.630351 beta-lactamase_0_D161F,beta-lactamase_0_161,TEM-1,beta-lactamase_0,P62593,0.630364,NO,161,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.891,-4.316,3.425,,0.341,,A,0.75,-0.52,0.795,,61.19,HAB,-0.961333,0.0500837,0.000897697,0.630364 kka2_1:2_A87P,kka2_1:2_87,Kka2,kka2_1:2,P00552,0.630459,NO,87,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.917,-2.939,1.022,,1.039,S,L,0.46,1.57,22.675,22.675,65.53,AHO,-1.822,0.295029,0.00791281,0.630459 kka2_1:1_R211C,kka2_1:1_211,Kka2,kka2_1:1,P00552,0.630493,NO,211,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-0.899,-5.114,4.215,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.520039,0.00204888,0.630493 beta-lactamase_156_H287P,beta-lactamase_156_287,TEM-1,beta-lactamase_156,P62593,0.630514,NO,287,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,,,,,,,,,,,,,BBH,-1.111,0.111618,,0.630514 PSD95pdz3_G330S,PSD95pdz3_330,PSD95pdz3,PSD95pdz3,P31016,0.6306,NO,330,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.008,-2.842,1.834,4.68351,,,,,31.405,,,,OOA,-1.14,0.0758425,0.000962386,0.6306 kka2_1:4_A144E,kka2_1:4_144,Kka2,kka2_1:4,P00552,0.630651,NO,144,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.859,-3.551,2.692,,,H,A,0.46,0.21,6.844,,52.65,BHB,-1.72933,0.168804,0.00231095,0.630651 beta-lactamase_T126Y,beta-lactamase_126,TEM-1,beta-lactamase,P62593,0.630661,NO,126,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.122,-4.294,3.172,4.82694,0.05,H,A,0.3,-0.05,1.14,,44.41,HPH,-1.60467,0.221079,0.00244552,0.630661 beta-lactamase_R241N,beta-lactamase_241,TEM-1,beta-lactamase,P62593,0.630669,NO,241,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.433,-2.333,0.9,5.02621,0.094,E,B,0.68,-0.16,1.327,,50,PBO,-1.42967,0.221079,0.00452736,0.630669 beta-lactamase_2500_Q204W,beta-lactamase_2500_204,TEM-1,beta-lactamase_2500,P62593,0.630713,NO,204,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-1.382,-5.303,3.921,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.361275,0.00364106,0.630713 beta-lactamase_A215C,beta-lactamase_215,TEM-1,beta-lactamase,P62593,0.630867,NO,215,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.503,-4.816,3.313,4.82164,,,a,0.75,-0.93,3.583,,74.48,HHO,-1.42633,0.221079,0.00544007,0.630867 beta-lactamase_625_G142Q,beta-lactamase_625_142,TEM-1,beta-lactamase_625,P62593,0.630882,NO,142,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.707,-4.087,3.38,,0.034,,p,0.29,-0.64,1.35,,64.69,OOO,-0.834,0.213352,0.00060149,0.630882 kka2_1:4_R66C,kka2_1:4_66,Kka2,kka2_1:4,P00552,0.630962,NO,66,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-0.922,-5.15,4.228,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.168804,0.00161025,0.630962 kka2_1:2_S114L,kka2_1:2_114,Kka2,kka2_1:2,P00552,0.630994,NO,114,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.527,-3.038,0.511,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.295029,0.00705262,0.630994 beta-lactamase_2500_Y103N,beta-lactamase_2500_103,TEM-1,beta-lactamase_2500,P62593,0.631019,NO,103,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-1.33,-2.825,1.495,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.361275,0.00443048,0.631019 beta-lactamase_R91I,beta-lactamase_91,TEM-1,beta-lactamase,P62593,0.631027,NO,91,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.392,-4.049,2.657,5.92536,0.444,,B,0.68,0.96,1.318,,50.35,OBB,-1.73367,0.221079,0.00380226,0.631027 beta-lactamase_0_A170I,beta-lactamase_0_170,TEM-1,beta-lactamase_0,P62593,0.631074,NO,170,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.237,-3.643,2.406,,0.126,,L,0.46,-0.35,2.427,,64.69,AHH,-1.63267,0.0500837,0.00431903,0.631074 beta-lactamase_T116G,beta-lactamase_116,TEM-1,beta-lactamase,P62593,0.631075,NO,116,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.28,-3.287,2.007,4.78335,0.115,E,B,0.69,-0.12,0.343,,67.48,HPH,-1.39967,0.221079,0.00336175,0.631075 kka2_1:1_Y218S,kka2_1:1_218,Kka2,kka2_1:1,P00552,0.631079,NO,218,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-1.438,-3.656,2.218,,0.122,H,A,1.25,-0.69,3.059,,56.06,BHP,-1.17533,0.520039,0.0126098,0.631079 beta-lactamase_V117P,beta-lactamase_117,TEM-1,beta-lactamase,P62593,0.63111,NO,117,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.53,-4.14,2.61,5.33594,,H,A,1.19,-0.34,1.182,,65.03,PHB,-1.741,0.221079,0.00467906,0.63111 kka2_1:1_L47Q,kka2_1:1_47,Kka2,kka2_1:1,P00552,0.631184,NO,47,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.265,-2.824,1.559,,0.139,E,B,0.55,-0.86,14.593,14.593,63.26,HHH,-1.77933,0.520039,0.00509386,0.631184 beta-lactamase_L192Q,beta-lactamase_192,TEM-1,beta-lactamase,P62593,0.631237,NO,192,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.254,-4.246,2.992,5.68899,0.095,H,A,1.3,0.35,1.756,,60.14,HHP,-1.41833,0.221079,0.00558728,0.631237 beta-lactamase_2500_D99R,beta-lactamase_2500_99,TEM-1,beta-lactamase_2500,P62593,0.631359,NO,99,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.191,-3.828,2.637,,0.402,G,A,0.75,0.36,1.318,,64.69,PAH,-1.794,0.361275,0.00305446,0.631359 kka2_1:1_V75M,kka2_1:1_75,Kka2,kka2_1:1,P00552,0.631379,NO,75,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-2.06,-2.759,0.699,,0.042,.,B,0.44,-0.2,2.815,,71.59,OHO,-1.563,0.520039,0.00693733,0.631379 kka2_1:8_D157Y,kka2_1:8_157,Kka2,kka2_1:8,P00552,0.631425,NO,157,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.993,-4.444,3.451,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.100394,0.0042313,0.631425 kka2_1:8_D157Y,kka2_1:8_157,Kka2,kka2_1:8,P00552,0.631425,NO,157,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.993,-4.444,3.451,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.100394,0.0042313,0.631425 kka2_1:1_T187A,kka2_1:1_187,Kka2,kka2_1:1,P00552,0.631452,NO,187,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.273,-1.915,0.642,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.520039,0.00693073,0.631452 kka2_1:8_S105P,kka2_1:8_105,Kka2,kka2_1:8,P00552,0.631529,NO,105,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.945,-3.155,1.21,,0.056,S,B,0.27,-1.04,2.115,,65.53,PPB,-2.17033,0.100394,0.00847233,0.631529 kka2_1:8_S105P,kka2_1:8_105,Kka2,kka2_1:8,P00552,0.631529,NO,105,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.945,-3.155,1.21,,0.056,S,B,0.27,-1.04,2.115,,65.53,PPB,-2.17033,0.100394,0.00847233,0.631529 kka2_1:1_A247P,kka2_1:1_247,Kka2,kka2_1:1,P00552,0.631547,NO,247,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.459,-2.362,-0.097,,1.01,S,A,0.46,0.65,7.731,7.731,92.05,HHH,-2.197,0.520039,0.0102428,0.631547 kka2_1:4_D159V,kka2_1:4_159,Kka2,kka2_1:4,P00552,0.631555,NO,159,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.82,-3.816,2.996,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.168804,0.0030485,0.631555 kka2_1:1_L47C,kka2_1:1_47,Kka2,kka2_1:1,P00552,0.631568,NO,47,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.265,-4.875,3.61,,0.139,E,B,0.55,-0.86,14.593,14.593,63.26,HHH,-1.77933,0.520039,0.00509386,0.631568 kka2_1:4_W236G,kka2_1:4_236,Kka2,kka2_1:4,P00552,0.631569,NO,236,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-1.363,-2.755,1.392,,0.303,H,A,0.47,-0.76,2.277,,48.48,AHH,-1.81267,0.168804,0.0088796,0.631569 beta-lactamase_156_A247R,beta-lactamase_156_247,TEM-1,beta-lactamase_156,P62593,0.631578,NO,247,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.111618,0.00611275,0.631578 beta-lactamase_156_L120G,beta-lactamase_156_120,TEM-1,beta-lactamase_156,P62593,0.631629,NO,120,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.044,-3.788,2.744,,,H,A,0.55,-1.13,7.813,,64.69,AHO,-1.13633,0.111618,0.00143563,0.631629 beta-lactamase_T126W,beta-lactamase_126,TEM-1,beta-lactamase,P62593,0.631674,NO,126,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.122,-5.243,4.121,4.82694,0.05,H,A,0.3,-0.05,1.14,,44.41,HPH,-1.60467,0.221079,0.00244552,0.631674 kka2_1:8_R211H,kka2_1:8_211,Kka2,kka2_1:8,P00552,0.631728,NO,211,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-0.899,-4.319,3.42,,0.12,T,a,0.16,-0.39,0.615,,49.62,OBH,-0.966,0.100394,0.00204888,0.631728 kka2_1:8_R211H,kka2_1:8_211,Kka2,kka2_1:8,P00552,0.631728,NO,211,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-0.899,-4.319,3.42,,0.12,T,a,0.16,-0.39,0.615,,49.62,OBH,-0.966,0.100394,0.00204888,0.631728 beta-lactamase_D174V,beta-lactamase_174,TEM-1,beta-lactamase,P62593,0.631816,NO,174,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.738,-3.754,3.016,5.44133,0.238,,B,1.22,-0.1,,,,PAA,-1.91233,0.221079,0.00125633,0.631816 kka2_1:1_L241P,kka2_1:1_241,Kka2,kka2_1:1,P00552,0.631839,NO,241,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.158,-4.275,3.117,,0.08,H,A,0.55,-0.82,1.685,,63.26,HHH,-1.58533,0.520039,0.0117299,0.631839 beta-lactamase_2500_E46D,beta-lactamase_2500_46,TEM-1,beta-lactamase_2500,P62593,0.63184,NO,46,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.94,-3.652,1.712,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.361275,0.00427568,0.63184 kka2_1:2_G30V,kka2_1:2_30,Kka2,kka2_1:2,P00552,0.631889,NO,30,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.596,-3.782,3.186,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.295029,0.00159208,0.631889 kka2_1:1_A150S,kka2_1:1_150,Kka2,kka2_1:1,P00552,0.631965,NO,150,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.949,-3.097,2.148,,0.544,T,A,0.46,1.34,2.333,,63.26,AHO,-1.272,0.520039,0.0045009,0.631965 beta-lactamase_2500_A215T,beta-lactamase_2500_215,TEM-1,beta-lactamase_2500,P62593,0.631969,NO,215,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.503,-2.291,0.788,,,,a,0.46,-0.93,3.516,,74.48,HHO,-1.42633,0.361275,0.00544007,0.631969 kka2_1:1_Q155D,kka2_1:1_155,Kka2,kka2_1:1,P00552,0.631981,NO,155,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.606,-2.377,-0.229,,0.525,T,A,0.4,1.49,4.415,,63.64,APA,-1.726,0.520039,0.00641853,0.631981 kka2_1:1_A64E,kka2_1:1_64,Kka2,kka2_1:1,P00552,0.632032,NO,64,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.496,-2.982,1.486,,0.039,H,A,0.46,-0.57,1.175,,56.06,AHH,-1.334,0.520039,0.00705578,0.632032 kka2_1:8_L158I,kka2_1:8_158,Kka2,kka2_1:8,P00552,0.632182,NO,158,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.947,-3.293,1.346,,0.095,.,B,0.55,0.77,1.607,,63.64,AHA,-1.25333,0.100394,0.00529068,0.632182 kka2_1:8_L158I,kka2_1:8_158,Kka2,kka2_1:8,P00552,0.632182,NO,158,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.947,-3.293,1.346,,0.095,.,B,0.55,0.77,1.607,,63.64,AHA,-1.25333,0.100394,0.00529068,0.632182 kka2_1:2_T85I,kka2_1:2_85,Kka2,kka2_1:2,P00552,0.632219,NO,85,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.165,-2.979,0.814,,0.576,E,B,0.22,1.39,1.853,,71.59,HPA,-2.10133,0.295029,0.00634493,0.632219 beta-lactamase_0_E35R,beta-lactamase_0_35,TEM-1,beta-lactamase_0,P62593,0.632268,NO,35,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-0.869,-3.551,2.682,,0.15,H,A,1.04,0.21,0.664,,46.85,HAA,-1.88667,0.0500837,0.00174441,0.632268 WW_domain_Q186V,WW_domain_186,Yap65,WW_domain,P46937,0.632358,NO,186,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-1.358,-3.306,1.948,4.88854,,,,,,,,,OPB,-1.207,0.153962,0.00161546,0.632358 beta-lactamase_A123N,beta-lactamase_123,TEM-1,beta-lactamase,P62593,0.632451,NO,123,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.834,-3.947,3.113,4.70061,0.039,H,A,0.52,-0.72,0.705,,41.26,PHH,-1.47367,0.221079,0.0010157,0.632451 kka2_1:4_Y244A,kka2_1:4_244,Kka2,kka2_1:4,P00552,0.632462,NO,244,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-0.775,-3.331,2.556,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.168804,0.00453187,0.632462 kka2_1:2_A65W,kka2_1:2_65,Kka2,kka2_1:2,P00552,0.632493,NO,65,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.744,-5.541,3.797,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.295029,0.00709258,0.632493 beta-lactamase_0_E35L,beta-lactamase_0_35,TEM-1,beta-lactamase_0,P62593,0.632529,NO,35,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-0.869,-3.632,2.763,,0.15,H,A,1.04,0.21,0.664,,46.85,HAA,-1.88667,0.0500837,0.00174441,0.632529 kka2_1:4_R38P,kka2_1:4_38,Kka2,kka2_1:4,P00552,0.632542,NO,38,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.207,-4.041,2.834,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.168804,0.00372499,0.632542 kka2_1:2_V186T,kka2_1:2_186,Kka2,kka2_1:2,P00552,0.63256,NO,186,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.011,-3.386,2.375,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.295029,0.00409703,0.63256 beta-lactamase_39_T179L,beta-lactamase_39_179,TEM-1,beta-lactamase_39,P62593,0.632595,NO,179,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.085,-3.263,2.178,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.0495842,0.00226045,0.632595 kka2_1:1_W15Q,kka2_1:1_15,Kka2,kka2_1:1,P00552,0.632738,NO,15,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-1.392,-4.279,2.887,,0.01,G,A,0.47,0.15,20.149,20.149,52.27,HHH,-2.10533,0.520039,0.00585505,0.632738 beta-lactamase_I140N,beta-lactamase_140,TEM-1,beta-lactamase,P62593,0.632773,NO,140,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.733,-4.2,2.467,5.29918,0.128,H,A,1,0.41,1.16,,73.08,PHO,-1.48733,0.221079,0.00597777,0.632773 beta-lactamase_156_V259E,beta-lactamase_156_259,TEM-1,beta-lactamase_156,P62593,0.632836,NO,259,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.111618,0.0070773,0.632836 kka2_1:4_E96D,kka2_1:4_96,Kka2,kka2_1:4,P00552,0.632878,NO,96,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.573,-3.69,1.117,,0.476,,B,1.52,-0.65,1.254,,71.59,OAH,-2.143,0.168804,0.00369441,0.632878 beta-lactamase_156_A235F,beta-lactamase_156_235,TEM-1,beta-lactamase_156,P62593,0.632925,NO,235,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.266,-4.199,2.933,,0.32,E,B,0.46,-0.86,1.344,,50,OHO,-0.89,0.111618,0.00493474,0.632925 kka2_1:1_L123M,kka2_1:1_123,Kka2,kka2_1:1,P00552,0.632935,NO,123,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.888,-2.619,1.731,,0.007,H,A,0.55,-0.4,1.447,,48.86,BHB,-1.301,0.520039,0.00325188,0.632935 kka2_1:2_Q27K,kka2_1:2_27,Kka2,kka2_1:2,P00552,0.632979,NO,27,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-1.659,-3.492,1.833,,0.608,.,A,0.64,0.71,0.521,,65.53,PPP,-1.90733,0.295029,0.00595365,0.632979 kka2_1:1_A25D,kka2_1:1_25,Kka2,kka2_1:1,P00552,0.632999,NO,25,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.496,-2.743,0.247,,0.427,E,B,0.46,-0.47,6.872,6.872,65.53,HHP,-2.15167,0.520039,0.00595636,0.632999 kka2_1:8_H124I,kka2_1:8_124,Kka2,kka2_1:8,P00552,0.633005,NO,124,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-0.84,-4.039,3.199,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.100394,0.00211296,0.633005 kka2_1:8_H124I,kka2_1:8_124,Kka2,kka2_1:8,P00552,0.633005,NO,124,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-0.84,-4.039,3.199,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.100394,0.00211296,0.633005 kka2_1:4_L19W,kka2_1:4_19,Kka2,kka2_1:4,P00552,0.633015,NO,19,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.254,-5.02,3.766,,0.08,T,A,1.59,-0.26,2.645,,65.53,BHH,-2.221,0.168804,0.00620703,0.633015 beta-lactamase_39_L248G,beta-lactamase_39_248,TEM-1,beta-lactamase_39,P62593,0.633182,NO,248,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.794,-3.512,1.718,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.0495842,0.00428493,0.633182 beta-lactamase_2500_V101G,beta-lactamase_2500_101,TEM-1,beta-lactamase_2500,P62593,0.633233,NO,101,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.295,-3.721,2.426,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.361275,0.00374492,0.633233 beta-lactamase_156_I277A,beta-lactamase_156_277,TEM-1,beta-lactamase_156,P62593,0.633307,NO,277,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.111618,0.0169305,0.633307 kka2_1:1_L57M,kka2_1:1_57,Kka2,kka2_1:1,P00552,0.633359,NO,57,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.898,-4.404,2.506,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.520039,0.00723769,0.633359 beta-lactamase_625_L47K,beta-lactamase_625_47,TEM-1,beta-lactamase_625,P62593,0.633548,NO,47,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.876,-3.656,1.78,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.213352,0.00439844,0.633548 kka2_1:2_G151A,kka2_1:2_151,Kka2,kka2_1:2,P00552,0.633549,NO,151,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.873,-3.018,2.145,,0.678,T,l,0.29,1.36,1.357,,49.62,HOH,-1.11433,0.295029,0.00339918,0.633549 kka2_1:4_L81P,kka2_1:4_81,Kka2,kka2_1:4,P00552,0.633569,NO,81,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.427,-4.19,2.763,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.168804,0.00805839,0.633569 beta-lactamase_39_I261G,beta-lactamase_39_261,TEM-1,beta-lactamase_39,P62593,0.633608,NO,261,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.0495842,0.0123091,0.633608 kka2_1:4_D62Y,kka2_1:4_62,Kka2,kka2_1:4,P00552,0.633651,NO,62,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.591,-4.391,2.8,,0.262,H,A,0.29,0.08,14.756,14.756,64.39,PAA,-1.77833,0.168804,0.00744243,0.633651 beta-lactamase_2500_G154A,beta-lactamase_2500_154,TEM-1,beta-lactamase_2500,P62593,0.633663,NO,154,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.823,-2.356,1.533,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.361275,0.00180205,0.633663 beta-lactamase_G141F,beta-lactamase_141,TEM-1,beta-lactamase,P62593,0.633796,NO,141,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.828,-4.352,3.524,5.03155,0.575,T,l,0.76,-0.28,0.198,,64.69,HOO,-1.08933,0.221079,0.0012419,0.633796 kka2_1:4_D183C,kka2_1:4_183,Kka2,kka2_1:4,P00552,0.633941,NO,183,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.204,-5.235,4.031,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.168804,0.00426304,0.633941 beta-lactamase_L146T,beta-lactamase_146,TEM-1,beta-lactamase,P62593,0.633944,NO,146,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.462,-3.533,2.071,5.62483,0.007,H,A,1.3,-0.56,1.953,,64.69,AHP,-1.656,0.221079,0.00474542,0.633944 beta-lactamase_0_L120Q,beta-lactamase_0_120,TEM-1,beta-lactamase_0,P62593,0.633994,NO,120,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.044,-4.124,3.08,,,H,A,0.55,-1.13,1.2,,64.69,AHO,-1.13633,0.0500837,0.00143563,0.633994 beta-lactamase_625_I140G,beta-lactamase_625_140,TEM-1,beta-lactamase_625,P62593,0.634005,NO,140,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.733,-3.828,2.095,,0.128,H,A,0.48,0.41,1.628,,73.08,PHO,-1.48733,0.213352,0.00597777,0.634005 beta-lactamase_2500_A170D,beta-lactamase_2500_170,TEM-1,beta-lactamase_2500,P62593,0.634072,NO,170,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.237,-3.712,2.475,,0.126,,L,0.46,-0.35,2.427,,64.69,AHH,-1.63267,0.361275,0.00431903,0.634072 kka2_1:1_D118Y,kka2_1:1_118,Kka2,kka2_1:1,P00552,0.634094,NO,118,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.07,-4.383,2.313,,0.61,H,A,0.75,-0.05,13.434,13.434,64.39,HAH,-1.32367,0.520039,0.0067852,0.634094 beta-lactamase_156_I280A,beta-lactamase_156_280,TEM-1,beta-lactamase_156,P62593,0.63418,NO,280,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.708,-4.017,2.309,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.111618,0.0530888,0.63418 kka2_1:4_V36L,kka2_1:4_36,Kka2,kka2_1:4,P00552,0.634185,NO,36,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-0.898,-2.711,1.813,,0.292,E,B,0.44,0.21,0.278,,52.27,HHH,-1.484,0.168804,0.00245633,0.634185 beta-lactamase_0_V31Y,beta-lactamase_0_31,TEM-1,beta-lactamase_0,P62593,0.634223,NO,31,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.822,-4.027,2.205,,,H,A,0.44,-0.46,4.126,,73.78,BHB,-2.03767,0.0500837,0.00478065,0.634223 kka2_1:8_F133C,kka2_1:8_133,Kka2,kka2_1:8,P00552,0.63424,NO,133,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-0.871,-4.914,4.043,,0.178,,B,1.62,0.43,1.816,,42.42,OHA,-0.871667,0.100394,0.00182168,0.63424 kka2_1:8_F133C,kka2_1:8_133,Kka2,kka2_1:8,P00552,0.63424,NO,133,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-0.871,-4.914,4.043,,0.178,,B,1.62,0.43,1.816,,42.42,OHA,-0.871667,0.100394,0.00182168,0.63424 beta-lactamase_625_Y262C,beta-lactamase_625_262,TEM-1,beta-lactamase_625,P62593,0.634326,NO,262,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.213352,0.00853516,0.634326 kka2_1:4_E111G,kka2_1:4_111,Kka2,kka2_1:4,P00552,0.634387,NO,111,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.28,-2.822,0.542,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.168804,0.00746789,0.634387 beta-lactamase_39_I244G,beta-lactamase_39_244,TEM-1,beta-lactamase_39,P62593,0.634404,NO,244,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.555,-3.714,2.159,,,E,B,0.48,-0.84,1.325,,77.62,OHH,-1.385,0.0495842,0.00605379,0.634404 kka2_1:1_D238V,kka2_1:1_238,Kka2,kka2_1:1,P00552,0.634411,NO,238,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.83,-3.676,0.846,,0.604,H,A,0.75,-0.33,11.329,11.329,92.05,HAB,-2.633,0.520039,0.0113863,0.634411 kka2_1:1_K50S,kka2_1:1_50,Kka2,kka2_1:1,P00552,0.634427,NO,50,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-0.833,-3.233,2.4,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.520039,0.00138626,0.634427 Pab1_K156Y,Pab1_156,Pab1,Pab1,P04147,0.634457,NO,156,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.083,-3.98,2.897,,0.406,E,B,1.82,-0.26,,,,PBH,-1.58167,0.175299,0.000316767,0.634457 beta-lactamase_156_F64L,beta-lactamase_156_64,TEM-1,beta-lactamase_156,P62593,0.634478,NO,64,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-0.841,-2.908,2.067,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.111618,0.000947691,0.634478 beta-lactamase_39_S233K,beta-lactamase_39_233,TEM-1,beta-lactamase_39,P62593,0.634485,NO,233,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.886,-3.496,1.61,,0.016,E,B,0.27,-1.01,5.361,,77.62,BPO,-1.17267,0.0495842,0.00311415,0.634485 beta-lactamase_F13K,beta-lactamase_13,TEM-1,beta-lactamase,P62593,0.63451,NO,13,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-2.394,-3.629,1.235,,,,,,,4.079,,77.62,OHH,-2.382,0.221079,0.0029078,0.63451 kka2_1:1_V198R,kka2_1:1_198,Kka2,kka2_1:1,P00552,0.634534,NO,198,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.719,-3.986,2.267,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.520039,0.00835002,0.634534 beta-lactamase_2500_A77D,beta-lactamase_2500_77,TEM-1,beta-lactamase_2500,P62593,0.634571,NO,77,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.234,-3.775,2.541,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.361275,0.00282362,0.634571 kka2_1:1_A79H,kka2_1:1_79,Kka2,kka2_1:1,P00552,0.634579,NO,79,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.368,-3.321,0.953,,0.563,.,B,0.46,-0.43,7.792,7.792,71.59,HHH,-1.752,0.520039,0.00664821,0.634579 kka2_1:8_D33I,kka2_1:8_33,Kka2,kka2_1:8,P00552,0.634591,NO,33,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.186,-4.175,1.989,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.100394,0.00633568,0.634591 kka2_1:8_D33I,kka2_1:8_33,Kka2,kka2_1:8,P00552,0.634591,NO,33,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.186,-4.175,1.989,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.100394,0.00633568,0.634591 kka2_1:1_T130S,kka2_1:1_130,Kka2,kka2_1:1,P00552,0.63462,NO,130,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.392,-2.025,-0.367,,0.561,G,A,0.22,0.77,0.5,,92.05,HPO,-1.62633,0.520039,0.00804204,0.63462 kka2_1:4_D159Q,kka2_1:4_159,Kka2,kka2_1:4,P00552,0.634688,NO,159,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.82,-3.79,2.97,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.168804,0.0030485,0.634688 beta-lactamase_0_V31H,beta-lactamase_0_31,TEM-1,beta-lactamase_0,P62593,0.634689,NO,31,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.822,-4.968,3.146,,,H,A,0.44,-0.46,4.126,,73.78,BHB,-2.03767,0.0500837,0.00478065,0.634689 beta-lactamase_156_V101P,beta-lactamase_156_101,TEM-1,beta-lactamase_156,P62593,0.63471,NO,101,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.295,-4.04,2.745,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.111618,0.00374492,0.63471 beta-lactamase_0_P25A,beta-lactamase_0_25,TEM-1,beta-lactamase_0,P62593,0.634736,NO,25,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.526,-2.222,0.696,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.0500837,0.00347571,0.634736 beta-lactamase_L136C,beta-lactamase_136,TEM-1,beta-lactamase,P62593,0.63475,NO,136,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.232,-4.751,3.519,5.31114,,H,A,2.89,-0.34,1.539,,48.95,HHH,-1.088,0.221079,0.00442304,0.63475 beta-lactamase_L150H,beta-lactamase_150,TEM-1,beta-lactamase,P62593,0.634886,NO,150,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.326,-4.935,3.609,5.15566,,H,A,1.75,-0.2,1.615,,62.94,HHB,-1.86167,0.221079,0.00463171,0.634886 kka2_1:8_I246P,kka2_1:8_246,Kka2,kka2_1:8,P00552,0.634891,NO,246,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-2.008,-3.255,1.247,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.100394,0.0139479,0.634891 kka2_1:8_I246P,kka2_1:8_246,Kka2,kka2_1:8,P00552,0.634891,NO,246,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-2.008,-3.255,1.247,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.100394,0.0139479,0.634891 kka2_1:2_G233L,kka2_1:2_233,Kka2,kka2_1:2,P00552,0.634964,NO,233,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.748,-3.881,3.133,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.295029,0.00232366,0.634964 kka2_1:1_D33Y,kka2_1:1_33,Kka2,kka2_1:1,P00552,0.635021,NO,33,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.186,-4.503,2.317,,0.561,S,A,0.75,3.35,2.568,,71.59,PAH,-1.306,0.520039,0.00633568,0.635021 kka2_1:4_L232C,kka2_1:4_232,Kka2,kka2_1:4,P00552,0.63509,NO,232,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.514,-3.424,1.91,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.168804,0.00800103,0.63509 beta-lactamase_0_A282S,beta-lactamase_0_282,TEM-1,beta-lactamase_0,P62593,0.635113,NO,282,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.0500837,0.0449821,0.635113 beta-lactamase_0_H151W,beta-lactamase_0_151,TEM-1,beta-lactamase_0,P62593,0.635141,NO,151,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-2.96,-5.334,2.374,,0.594,H,A,0.17,0.1,9.375,,77.62,HBP,-2.34767,0.0500837,0.00216946,0.635141 beta-lactamase_T69P,beta-lactamase_69,TEM-1,beta-lactamase,P62593,0.635173,NO,69,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-0.973,-3.715,2.742,5.16042,,G,A,0.69,-1.24,0.505,,93.01,PPH,-1.01833,0.221079,0.00127498,0.635173 beta-lactamase_39_M209Q,beta-lactamase_39_209,TEM-1,beta-lactamase_39,P62593,0.635193,NO,209,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.442,-3.974,2.532,,,H,A,0.55,-0.97,1.167,,64.69,HHA,-1.52633,0.0495842,0.00625021,0.635193 beta-lactamase_625_E35V,beta-lactamase_625_35,TEM-1,beta-lactamase_625,P62593,0.635251,NO,35,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-0.869,-3.578,2.709,,0.15,H,A,1.04,0.21,0.664,,46.85,HAA,-1.88667,0.213352,0.00174441,0.635251 kka2_1:2_L47W,kka2_1:2_47,Kka2,kka2_1:2,P00552,0.635285,NO,47,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.265,-5.21,3.945,,0.139,E,B,0.55,-0.86,2.369,,63.26,HHH,-1.77933,0.295029,0.00509386,0.635285 kka2_1:2_P98C,kka2_1:2_98,Kka2,kka2_1:2,P00552,0.635301,NO,98,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.526,-5.171,3.645,,0.391,S,B,0.52,-0.65,2.82,,63.26,HOO,-1.19167,0.295029,0.00622754,0.635301 beta-lactamase_2500_F228S,beta-lactamase_2500_228,TEM-1,beta-lactamase_2500,P62593,0.635324,NO,228,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-2.342,-3.492,1.15,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.361275,0.0046669,0.635324 beta-lactamase_L79F,beta-lactamase_79,TEM-1,beta-lactamase,P62593,0.635423,NO,79,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.842,-3.643,2.801,4.98681,0.007,H,A,1.07,-0.16,0.823,,50.35,HHP,-1.44333,0.221079,0.000947397,0.635423 kka2_1:4_T225D,kka2_1:4_225,Kka2,kka2_1:4,P00552,0.635425,NO,225,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.393,-3.922,1.529,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.168804,0.0113598,0.635425 beta-lactamase_0_A40F,beta-lactamase_0_40,TEM-1,beta-lactamase_0,P62593,0.635483,NO,40,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.402,-4.227,2.825,,0.155,S,B,0.46,0.21,0.783,,73.78,OHB,-1.40267,0.0500837,0.00490026,0.635483 Pab1_K131H,Pab1_131,Pab1,Pab1,P04147,0.635578,NO,131,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.083,-4.272,3.189,,0.462,E,B,1.82,0.57,,,,HBP,-1.12467,0.175299,0.000349395,0.635578 kka2_1:1_R66C,kka2_1:1_66,Kka2,kka2_1:1,P00552,0.63562,NO,66,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-0.922,-5.15,4.228,,0.103,H,A,1.2,-0.2,2.659,,46.21,HBH,-1.13567,0.520039,0.00161025,0.63562 kka2_1:8_L174P,kka2_1:8_174,Kka2,kka2_1:8,P00552,0.635639,NO,174,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.952,-4.115,3.163,,,H,A,1.59,-0.31,1.204,,51.89,BHB,-2.08533,0.100394,0.00438501,0.635639 kka2_1:8_L174P,kka2_1:8_174,Kka2,kka2_1:8,P00552,0.635639,NO,174,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.952,-4.115,3.163,,,H,A,1.59,-0.31,1.204,,51.89,BHB,-2.08533,0.100394,0.00438501,0.635639 gb1_G267A,gb1_267,gb1,gb1,P06654,0.635799,NO,267,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.676,-2.021,0.345,,,,,,,1.361,,12.72,AOA,-1.61833,0.177985,0.00264655,0.635799 beta-lactamase_D212E,beta-lactamase_212,TEM-1,beta-lactamase,P62593,0.635943,NO,212,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.624,-3.306,1.682,4.9705,0.037,,b,1.3,-0.58,12.482,,74.48,HAB,-1.77667,0.221079,0.00644302,0.635943 kka2_1:2_S32I,kka2_1:2_32,Kka2,kka2_1:2,P00552,0.635964,NO,32,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-0.804,-3.814,3.01,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.295029,0.00149998,0.635964 kka2_1:2_W24S,kka2_1:2_24,Kka2,kka2_1:2,P00552,0.636063,NO,24,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-1.779,-2.861,1.082,,0.477,E,B,1.51,-0.21,2.666,,56.06,AHH,-2.24467,0.295029,0.00631564,0.636063 kka2_1:2_A78S,kka2_1:2_78,Kka2,kka2_1:2,P00552,0.636129,NO,78,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.744,-3.309,1.565,,0.078,.,B,0.46,-0.53,0.206,,56.06,OHH,-1.863,0.295029,0.00457299,0.636129 beta-lactamase_625_G265V,beta-lactamase_625_265,TEM-1,beta-lactamase_625,P62593,0.636156,NO,265,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.213352,0.00811926,0.636156 PSD95pdz3_I388K,PSD95pdz3_388,PSD95pdz3,PSD95pdz3,P31016,0.636258,NO,388,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.63,-3.589,1.959,5.17282,,,,,16.0025,,,,PHH,-1.54967,0.0758425,0.000151216,0.636258 kka2_1:2_W15S,kka2_1:2_15,Kka2,kka2_1:2,P00552,0.636326,NO,15,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-1.392,-3.829,2.437,,0.01,G,A,0.47,0.15,2.586,,52.27,HHH,-2.10533,0.295029,0.00585505,0.636326 kka2_1:4_I115K,kka2_1:4_115,Kka2,kka2_1:4,P00552,0.6364,NO,115,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.606,-3.902,2.296,,0.105,H,A,1.52,-1.18,9.996,9.996,65.53,PHH,-2.205,0.168804,0.00836567,0.6364 beta-lactamase_625_R220A,beta-lactamase_625_220,TEM-1,beta-lactamase_625,P62593,0.636423,NO,220,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-0.942,-2.357,1.415,,0.295,I,A,1.2,-0.76,5.086,,74.48,HBP,-1.33633,0.213352,0.00232421,0.636423 beta-lactamase_156_L223E,beta-lactamase_156_223,TEM-1,beta-lactamase_156,P62593,0.636451,NO,223,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.055,-3.868,2.813,,0.27,,B,0.55,0.09,1.511,,74.48,HHO,-1.35033,0.111618,0.00372793,0.636451 kka2_1:4_G210S,kka2_1:4_210,Kka2,kka2_1:4,P00552,0.636531,NO,210,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.095,-1.997,0.902,,0.103,T,A,0.29,-0.62,0.271,,50,OOB,-0.966667,0.168804,0.00598378,0.636531 kka2_1:2_R147L,kka2_1:2_147,Kka2,kka2_1:2,P00552,0.636676,NO,147,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.123,-3.547,2.424,,0.094,H,A,1.2,0.97,0.425,,64.02,PBH,-1.98267,0.295029,0.00549168,0.636676 kka2_1:4_G233L,kka2_1:4_233,Kka2,kka2_1:4,P00552,0.636679,NO,233,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.748,-3.881,3.133,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.168804,0.00232366,0.636679 beta-lactamase_156_N274K,beta-lactamase_156_274,TEM-1,beta-lactamase_156,P62593,0.636681,NO,274,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.111618,0.0110418,0.636681 beta-lactamase_2500_I54C,beta-lactamase_2500_54,TEM-1,beta-lactamase_2500,P62593,0.636764,NO,54,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-2.838,-5.056,2.218,,0.669,E,B,0.48,-0.14,3.946,,73.78,BHH,-2.337,0.361275,0.00403589,0.636764 kka2_1:8_L193S,kka2_1:8_193,Kka2,kka2_1:8,P00552,0.636982,NO,193,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.983,-3.624,2.641,,,G,A,1.59,-1.03,2.234,,65.53,OHO,-0.965333,0.100394,0.00480179,0.636982 kka2_1:8_L193S,kka2_1:8_193,Kka2,kka2_1:8,P00552,0.636982,NO,193,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.983,-3.624,2.641,,,G,A,1.59,-1.03,2.234,,65.53,OHO,-0.965333,0.100394,0.00480179,0.636982 Ubiquitin_L15P,Ubiquitin_15,Uba1,Ubiquitin,P0CG48,0.637097,NO,15,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.082,-4.088,3.006,5.14718,0.029,E,B,1.16,-0.53,0.936,,38.69,PHA,-1.40833,0.205827,0.000519738,0.637097 Ubiquitin_Q2C,Ubiquitin_2,Uba1,Ubiquitin,P0CG48,0.637097,NO,2,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-1.7,-4.997,3.297,4.89203,0.475,E,B,,0.1,,,,OPH,-1.551,0.205827,0.00085006,0.637097 kka2_1:4_E63D,kka2_1:4_63,Kka2,kka2_1:4,P00552,0.637138,NO,63,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-0.762,-2.822,2.06,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.168804,0.00118399,0.637138 kka2_1:1_A137Y,kka2_1:1_137,Kka2,kka2_1:1,P00552,0.637202,NO,137,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.156,-4.084,1.928,,0.029,H,A,0.46,0.34,1.323,,63.26,PHB,-2.559,0.520039,0.00515054,0.637202 beta-lactamase_0_T69W,beta-lactamase_0_69,TEM-1,beta-lactamase_0,P62593,0.637211,NO,69,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-0.973,-5.208,4.235,,,G,A,0.22,-1.24,0.505,,93.01,PPH,-1.01833,0.0500837,0.00127498,0.637211 PSD95pdz3_G324K,PSD95pdz3_324,PSD95pdz3,PSD95pdz3,P31016,0.637212,NO,324,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.008,-3.364,2.356,4.98881,,,,,10.4525,,,,HOH,-1.293,0.0758425,0.00103462,0.637212 beta-lactamase_L74E,beta-lactamase_74,TEM-1,beta-lactamase,P62593,0.637227,NO,74,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.296,-3.786,2.49,5.50288,,H,A,1.75,-0.91,1.581,,50,HHO,-1.34933,0.221079,0.00493255,0.637227 kka2_1:8_D159A,kka2_1:8_159,Kka2,kka2_1:8,P00552,0.63723,NO,159,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.82,-3.286,2.466,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.100394,0.0030485,0.63723 kka2_1:8_D159A,kka2_1:8_159,Kka2,kka2_1:8,P00552,0.63723,NO,159,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.82,-3.286,2.466,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.100394,0.0030485,0.63723 kka2_1:1_R89G,kka2_1:1_89,Kka2,kka2_1:1,P00552,0.637256,NO,89,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.548,-2.87,1.322,,0.209,E,B,0.16,1.41,14.396,14.396,64.39,OBA,-1.89867,0.520039,0.00524373,0.637256 beta-lactamase_2500_L55Q,beta-lactamase_2500_55,TEM-1,beta-lactamase_2500,P62593,0.637282,NO,55,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.86,-3.156,1.296,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.361275,0.00403741,0.637282 gb1_F278Y,gb1_278,gb1,gb1,P06654,0.637339,NO,278,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.418,-3.092,1.674,,,,,,,3.233,,35.71,PHP,-1.503,0.177985,0.00295699,0.637339 gb1_L238P,gb1_238,gb1,gb1,P06654,0.637339,NO,238,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-2.98,-3.731,0.751,,,,,,,0.504,,45.54,PHB,-2.58633,0.177985,0.00205885,0.637339 kka2_1:1_Q61E,kka2_1:1_61,Kka2,kka2_1:1,P00552,0.637434,NO,61,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.982,-2.773,-0.209,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.520039,0.00612092,0.637434 kka2_1:1_T130N,kka2_1:1_130,Kka2,kka2_1:1,P00552,0.637447,NO,130,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.392,-2.756,0.364,,0.561,G,A,0.22,0.77,0.5,,92.05,HPO,-1.62633,0.520039,0.00804204,0.637447 beta-lactamase_2500_S57I,beta-lactamase_2500_57,TEM-1,beta-lactamase_2500,P62593,0.637453,NO,57,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.918,-3.825,1.907,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.361275,0.00492804,0.637453 beta-lactamase_0_Y262T,beta-lactamase_0_262,TEM-1,beta-lactamase_0,P62593,0.637454,NO,262,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-1.332,-4.271,2.939,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.0500837,0.00853516,0.637454 kka2_1:1_V186A,kka2_1:1_186,Kka2,kka2_1:1,P00552,0.637479,NO,186,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.011,-3.042,2.031,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.520039,0.00409703,0.637479 beta-lactamase_A235Q,beta-lactamase_235,TEM-1,beta-lactamase,P62593,0.637616,NO,235,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.266,-4.018,2.752,4.83024,0.32,E,B,0.52,-0.86,1.344,,50,OHO,-0.89,0.221079,0.00493474,0.637616 beta-lactamase_625_S266F,beta-lactamase_625_266,TEM-1,beta-lactamase_625,P62593,0.637641,NO,266,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.213352,0.0140785,0.637641 kka2_1:4_N200L,kka2_1:4_200,Kka2,kka2_1:4,P00552,0.637705,NO,200,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-2.446,-3.814,1.368,,0.756,T,L,0.61,-0.08,1.746,,64.39,APO,-2.08,0.168804,0.00838549,0.637705 beta-lactamase_39_L73K,beta-lactamase_39_73,TEM-1,beta-lactamase_39,P62593,0.637724,NO,73,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.507,-3.846,2.339,,,H,A,0.55,-0.64,2.09,,67.83,HHH,-1.487,0.0495842,0.00488983,0.637724 kka2_1:1_N200V,kka2_1:1_200,Kka2,kka2_1:1,P00552,0.637841,NO,200,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-2.446,-3.862,1.416,,0.756,T,L,0.61,-0.08,17.299,17.299,64.39,APO,-2.08,0.520039,0.00838549,0.637841 kka2_1:8_A215P,kka2_1:8_215,Kka2,kka2_1:8,P00552,0.637863,NO,215,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.968,-3.768,2.8,,0.039,E,B,1.04,-0.59,2.77,,50.38,HHA,-1.00467,0.100394,0.00529129,0.637863 kka2_1:8_A215P,kka2_1:8_215,Kka2,kka2_1:8,P00552,0.637863,NO,215,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.968,-3.768,2.8,,0.039,E,B,1.04,-0.59,2.77,,50.38,HHA,-1.00467,0.100394,0.00529129,0.637863 beta-lactamase_2500_E61C,beta-lactamase_2500_61,TEM-1,beta-lactamase_2500,P62593,0.637938,NO,61,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.115,-5.186,3.071,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.361275,0.00440955,0.637938 beta-lactamase_2500_N50C,beta-lactamase_2500_50,TEM-1,beta-lactamase_2500,P62593,0.638024,NO,50,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-2.979,-5.044,2.065,,0.912,T,A,0.61,1.24,1.581,,77.62,HPP,-2.134,0.361275,0.0047211,0.638024 kka2_1:2_R66S,kka2_1:2_66,Kka2,kka2_1:2,P00552,0.638068,NO,66,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-0.922,-3.412,2.49,,0.103,H,A,1.2,-0.2,2.659,,46.21,HBH,-1.13567,0.295029,0.00161025,0.638068 kka2_1:1_P128L,kka2_1:1_128,Kka2,kka2_1:1,P00552,0.63811,NO,128,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.922,-2.383,0.461,,0.316,G,A,0.52,0.4,2.178,,56.06,AOH,-1.64733,0.520039,0.00774689,0.63811 beta-lactamase_G114D,beta-lactamase_114,TEM-1,beta-lactamase,P62593,0.638144,NO,114,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.094,-3.551,2.457,4.92659,0.011,,p,0.77,0.35,2.148,,41.61,AOH,-1.43733,0.221079,0.00224919,0.638144 E1_Ubiquitin_R72W,E1_Ubiquitin_72,Uba1,E1_Ubiquitin,P0CG63,0.638373,NO,72,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.184,-5.14,3.956,,0.077,,B,0.16,-0.1,,,,HBH,-1.08733,0.18783,0.00129853,0.638373 kka2_1:1_E111V,kka2_1:1_111,Kka2,kka2_1:1,P00552,0.638488,NO,111,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.28,-2.806,0.526,,0.155,H,A,1.52,-1.14,15.716,15.716,65.53,HAB,-2.27833,0.520039,0.00746789,0.638488 PSD95pdz3_I359S,PSD95pdz3_359,PSD95pdz3,PSD95pdz3,P31016,0.63852,NO,359,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.63,-3.292,1.662,5.35151,,,,,14.8012,,,,PHH,-1.58667,0.0758425,0.000580694,0.63852 kka2_1:1_V153M,kka2_1:1_153,Kka2,kka2_1:1,P00552,0.638596,NO,153,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.092,-4.165,3.073,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.520039,0.00501119,0.638596 kka2_1:4_Y218V,kka2_1:4_218,Kka2,kka2_1:4,P00552,0.63861,NO,218,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-1.438,-3.601,2.163,,0.122,H,A,0.21,-0.69,1.022,,56.06,BHP,-1.17533,0.168804,0.0126098,0.63861 kka2_1:1_H135R,kka2_1:1_135,Kka2,kka2_1:1,P00552,0.638687,NO,135,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-1.331,-2.597,1.266,,0.071,.,a,0.17,0.65,3.574,,53.03,ABP,-1.77367,0.520039,0.00532566,0.638687 beta-lactamase_0_G142I,beta-lactamase_0_142,TEM-1,beta-lactamase_0,P62593,0.638716,NO,142,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.707,-4.199,3.492,,0.034,,p,0.29,-0.64,1.947,,64.69,OOO,-0.834,0.0500837,0.00060149,0.638716 beta-lactamase_2500_A222L,beta-lactamase_2500_222,TEM-1,beta-lactamase_2500,P62593,0.638758,NO,222,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.103,-3.403,1.3,,0.233,H,A,0.46,-0.25,0.379,,77.62,PHH,-1.63733,0.361275,0.00466094,0.638758 kka2_1:8_E262C,kka2_1:8_262,Kka2,kka2_1:8,P00552,0.63877,NO,262,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-0.829,-5.339,4.51,,0.059,G,A,1.52,-0.18,0.837,,42.42,AAH,-0.816,0.100394,0.0191586,0.63877 kka2_1:8_E262C,kka2_1:8_262,Kka2,kka2_1:8,P00552,0.63877,NO,262,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-0.829,-5.339,4.51,,0.059,G,A,1.52,-0.18,0.837,,42.42,AAH,-0.816,0.100394,0.0191586,0.63877 kka2_1:1_L39M,kka2_1:1_39,Kka2,kka2_1:1,P00552,0.638783,NO,39,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.223,-4.14,2.917,,,E,B,0.55,-1.21,0.925,,71.59,BHP,-1.69167,0.520039,0.00493618,0.638783 kka2_1:8_A119S,kka2_1:8_119,Kka2,kka2_1:8,P00552,0.638813,NO,119,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.073,-2.181,1.108,,0.019,H,A,0.46,-0.57,1.511,,71.59,AHH,-2.34,0.100394,0.00441074,0.638813 kka2_1:8_A119S,kka2_1:8_119,Kka2,kka2_1:8,P00552,0.638813,NO,119,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.073,-2.181,1.108,,0.019,H,A,0.46,-0.57,1.511,,71.59,AHH,-2.34,0.100394,0.00441074,0.638813 Pab1_A199F,Pab1_199,Pab1,Pab1,P04147,0.638818,NO,199,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.53,-4.074,2.544,,,,,,,1.479,,80.42,HHO,-1.50467,0.175299,0.00145024,0.638818 kka2_1:2_V49G,kka2_1:2_49,Kka2,kka2_1:2,P00552,0.638833,NO,49,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.614,-3.739,2.125,,,E,B,0.44,-0.77,1.233,,64.39,HHB,-1.3,0.295029,0.00615685,0.638833 beta-lactamase_2500_E62F,beta-lactamase_2500_62,TEM-1,beta-lactamase_2500,P62593,0.638867,NO,62,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.193,-4.376,3.183,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.361275,0.00264802,0.638867 kka2_1:4_R217L,kka2_1:4_217,Kka2,kka2_1:4,P00552,0.638914,NO,217,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.158,-2.651,1.493,,0.252,T,A,1.2,-0.59,2.074,,52.27,ABH,-1.127,0.168804,0.0047191,0.638914 beta-lactamase_2500_G216Y,beta-lactamase_2500_216,TEM-1,beta-lactamase_2500,P62593,0.639175,NO,216,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.477,-4.44,2.963,,0.437,I,A,0.29,-0.58,1.983,,74.48,HOO,-1.68067,0.361275,0.00639568,0.639175 kka2_1:8_L174F,kka2_1:8_174,Kka2,kka2_1:8,P00552,0.639208,NO,174,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.952,-3.775,2.823,,,H,A,1.59,-0.31,1.204,,51.89,BHB,-2.08533,0.100394,0.00438501,0.639208 kka2_1:8_L174F,kka2_1:8_174,Kka2,kka2_1:8,P00552,0.639208,NO,174,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.952,-3.775,2.823,,,H,A,1.59,-0.31,1.204,,51.89,BHB,-2.08533,0.100394,0.00438501,0.639208 kka2_1:4_L57N,kka2_1:4_57,Kka2,kka2_1:4,P00552,0.639226,NO,57,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.898,-4.124,2.226,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.168804,0.00723769,0.639226 kka2_1:8_D101G,kka2_1:8_101,Kka2,kka2_1:8,P00552,0.639257,NO,101,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.028,-3.238,2.21,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.100394,0.00423361,0.639257 kka2_1:8_D101G,kka2_1:8_101,Kka2,kka2_1:8,P00552,0.639257,NO,101,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.028,-3.238,2.21,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.100394,0.00423361,0.639257 beta-lactamase_625_D161I,beta-lactamase_625_161,TEM-1,beta-lactamase_625,P62593,0.639357,NO,161,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.891,-4.034,3.143,,0.341,,A,0.75,-0.52,4.655,,61.19,HAB,-0.961333,0.213352,0.000897697,0.639357 beta-lactamase_V29Y,beta-lactamase_29,TEM-1,beta-lactamase,P62593,0.639449,NO,29,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-2.856,-4.329,1.473,5.58481,0.733,H,A,0.23,-0.78,1.287,,93.01,HHB,-2.24733,0.221079,0.00318969,0.639449 beta-lactamase_2500_E62Y,beta-lactamase_2500_62,TEM-1,beta-lactamase_2500,P62593,0.639565,NO,62,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.193,-4.285,3.092,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.361275,0.00264802,0.639565 kka2_1:2_C31Y,kka2_1:2_31,Kka2,kka2_1:2,P00552,0.639574,NO,31,C,Y,CY,Special,Hydrophobic,5.07,5.66,0.59,194,121,181,60,108.5,193.6,85.1,-2.246,-4.264,2.018,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.295029,0.00681582,0.639574 beta-lactamase_625_A247H,beta-lactamase_625_247,TEM-1,beta-lactamase_625,P62593,0.639624,NO,247,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.213352,0.00611275,0.639624 kka2_1:4_R226C,kka2_1:4_226,Kka2,kka2_1:4,P00552,0.639725,NO,226,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.392,-5.171,3.779,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.168804,0.0108032,0.639725 kka2_1:4_G213R,kka2_1:4_213,Kka2,kka2_1:4,P00552,0.63974,NO,213,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.596,-3.961,3.365,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.168804,0.00187654,0.63974 beta-lactamase_0_T186Q,beta-lactamase_0_186,TEM-1,beta-lactamase_0,P62593,0.639788,NO,186,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.522,-2.514,-0.008,,0.396,H,A,0.22,-0.28,16.606,16.606,77.62,HPP,-1.77633,0.0500837,0.00485034,0.639788 beta-lactamase_2500_P165C,beta-lactamase_2500_165,TEM-1,beta-lactamase_2500,P62593,0.639836,NO,165,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.373,-4.892,3.519,,0.203,T,A,0.52,-0.31,0.414,,73.78,AOA,-1.359,0.361275,0.00549538,0.639836 kka2_1:2_A247W,kka2_1:2_247,Kka2,kka2_1:2,P00552,0.639837,NO,247,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.459,-5.465,3.006,,1.01,S,A,0.46,0.65,0.828,,92.05,HHH,-2.197,0.295029,0.0102428,0.639837 kka2_1:4_R38G,kka2_1:4_38,Kka2,kka2_1:4,P00552,0.639854,NO,38,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.207,-3.596,2.389,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.168804,0.00372499,0.639854 beta-lactamase_156_I93P,beta-lactamase_156_93,TEM-1,beta-lactamase_156,P62593,0.639925,NO,93,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.401,-2.926,1.525,,0.128,E,B,0.48,0.44,1.524,,67.83,BHB,-1.873,0.111618,0.00527066,0.639925 beta-lactamase_2500_I229L,beta-lactamase_2500_229,TEM-1,beta-lactamase_2500,P62593,0.639978,NO,229,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.267,-2.225,0.958,,0.083,E,B,0.48,-0.76,3.875,,50,HHH,-1.58767,0.361275,0.00477249,0.639978 beta-lactamase_0_S68M,beta-lactamase_0_68,TEM-1,beta-lactamase_0,P62593,0.640011,NO,68,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-0.913,-4.529,3.616,,0.064,G,A,0.27,-1.03,1.441,,64.69,HPP,-1.37233,0.0500837,0.000800065,0.640011 kka2_1:4_D227V,kka2_1:4_227,Kka2,kka2_1:4,P00552,0.640292,NO,227,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.758,-3.661,1.903,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.168804,0.00745029,0.640292 beta-lactamase_2500_T198V,beta-lactamase_2500_198,TEM-1,beta-lactamase_2500,P62593,0.640375,NO,198,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.168,-2.827,0.659,,0.489,,B,0.22,-0.13,0.37,,73.78,HPH,-1.98767,0.361275,0.004311,0.640375 gb1_V280Q,gb1_280,gb1,gb1,P06654,0.640375,NO,280,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.764,-3.899,2.135,,,,,,,0.874,,35.71,PHP,-1.63733,0.177985,0.00321577,0.640375 kka2_1:4_G245S,kka2_1:4_245,Kka2,kka2_1:4,P00552,0.64055,NO,245,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.812,-3.212,2.4,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.168804,0.00683899,0.64055 beta-lactamase_2500_V214C,beta-lactamase_2500_214,TEM-1,beta-lactamase_2500,P62593,0.640551,NO,214,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.299,-4.725,3.426,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.361275,0.00628442,0.640551 beta-lactamase_39_T107Q,beta-lactamase_39_107,TEM-1,beta-lactamase_39,P62593,0.640651,NO,107,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.117,-3.889,2.772,,,G,A,0.22,-0.06,2.686,,67.83,HPA,-1.265,0.0495842,0.00239347,0.640651 beta-lactamase_2500_I258C,beta-lactamase_2500_258,TEM-1,beta-lactamase_2500,P62593,0.640711,NO,258,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.361275,0.007931,0.640711 kka2_1:1_N200L,kka2_1:1_200,Kka2,kka2_1:1,P00552,0.640774,NO,200,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-2.446,-3.814,1.368,,0.756,T,L,0.61,-0.08,17.299,17.299,64.39,APO,-2.08,0.520039,0.00838549,0.640774 kka2_1:4_W91L,kka2_1:4_91,Kka2,kka2_1:4,P00552,0.640883,NO,91,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-1.178,-3.365,2.187,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.168804,0.00358653,0.640883 kka2_1:2_R258H,kka2_1:2_258,Kka2,kka2_1:2,P00552,0.641058,NO,258,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.626,-4.623,2.997,,0.316,H,A,1.2,-0.85,7.485,7.485,53.03,HBH,-1.25933,0.295029,0.00983174,0.641058 beta-lactamase_39_I245E,beta-lactamase_39_245,TEM-1,beta-lactamase_39,P62593,0.641084,NO,245,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.0495842,0.00391032,0.641084 kka2_1:2_I207M,kka2_1:2_207,Kka2,kka2_1:2,P00552,0.641114,NO,207,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.175,-4.117,2.942,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.295029,0.00611824,0.641114 beta-lactamase_625_P65V,beta-lactamase_625_65,TEM-1,beta-lactamase_625,P62593,0.641132,NO,65,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.894,-3.39,2.496,,0.098,E,B,0.52,-0.62,0.3,,40.56,HOH,-1.03233,0.213352,0.00152776,0.641132 beta-lactamase_0_P224I,beta-lactamase_0_224,TEM-1,beta-lactamase_0,P62593,0.641163,NO,224,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.893,-4.034,3.141,,0.383,,B,0.52,-0.3,3.587,,74.48,HOH,-1.26433,0.0500837,0.00189564,0.641163 beta-lactamase_0_T186K,beta-lactamase_0_186,TEM-1,beta-lactamase_0,P62593,0.641244,NO,186,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.522,-2.678,0.156,,0.396,H,A,0.22,-0.28,16.606,16.606,77.62,HPP,-1.77633,0.0500837,0.00485034,0.641244 beta-lactamase_0_S128Q,beta-lactamase_0_128,TEM-1,beta-lactamase_0,P62593,0.641276,NO,128,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-0.84,-3.674,2.834,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.0500837,0.00071483,0.641276 kka2_1:4_D134C,kka2_1:4_134,Kka2,kka2_1:4,P00552,0.641289,NO,134,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.969,-5.129,4.16,,0.421,B,B,0.75,0.31,0.733,,49.62,HAB,-1.057,0.168804,0.00270812,0.641289 kka2_1:4_G201H,kka2_1:4_201,Kka2,kka2_1:4,P00552,0.64139,NO,201,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.56,-3.46,1.9,,0.149,T,l,0.29,-0.57,0.284,,52.65,POB,-1.92233,0.168804,0.00820117,0.64139 beta-lactamase_39_L188K,beta-lactamase_39_188,TEM-1,beta-lactamase_39,P62593,0.641413,NO,188,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.166,-3.695,2.529,,,H,A,0.55,-0.3,2.982,,60.14,PHB,-1.47033,0.0495842,0.00295687,0.641413 Pab1_L186P,Pab1_186,Pab1,Pab1,P04147,0.641514,NO,186,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.783,-3.95,2.167,,,,,,,,,,HHP,-1.56967,0.175299,0.00154968,0.641514 kka2_1:8_H188S,kka2_1:8_188,Kka2,kka2_1:8,P00552,0.641566,NO,188,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-0.913,-3.412,2.499,,0.006,,A,0.87,-1.02,1.241,,47.73,PBO,-0.927333,0.100394,0.00273139,0.641566 kka2_1:8_H188S,kka2_1:8_188,Kka2,kka2_1:8,P00552,0.641566,NO,188,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-0.913,-3.412,2.499,,0.006,,A,0.87,-1.02,1.241,,47.73,PBO,-0.927333,0.100394,0.00273139,0.641566 kka2_1:2_Q100D,kka2_1:2_100,Kka2,kka2_1:2,P00552,0.641651,NO,100,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.77,-3.173,0.403,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.295029,0.0066405,0.641651 kka2_1:1_A191S,kka2_1:1_191,Kka2,kka2_1:1,P00552,0.641669,NO,191,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.831,-3.052,2.221,,,.,b,0.46,-0.94,0.53,,50,AHO,-0.868667,0.520039,0.00338807,0.641669 beta-lactamase_2500_G154K,beta-lactamase_2500_154,TEM-1,beta-lactamase_2500,P62593,0.641801,NO,154,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.823,-3.683,2.86,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.361275,0.00180205,0.641801 kka2_1:1_E111Q,kka2_1:1_111,Kka2,kka2_1:1,P00552,0.641886,NO,111,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.28,-2.347,0.067,,0.155,H,A,1.52,-1.14,15.716,15.716,65.53,HAB,-2.27833,0.520039,0.00746789,0.641886 kka2_1:2_S204M,kka2_1:2_204,Kka2,kka2_1:2,P00552,0.641888,NO,204,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.353,-4.656,3.303,,0.144,E,A,0.27,-1.2,2.442,,65.53,HPO,-0.953333,0.295029,0.00881794,0.641888 kka2_1:2_I228Q,kka2_1:2_228,Kka2,kka2_1:2,P00552,0.641901,NO,228,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.142,-4.362,3.22,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.295029,0.00458834,0.641901 beta-lactamase_2500_I54R,beta-lactamase_2500_54,TEM-1,beta-lactamase_2500,P62593,0.642013,NO,54,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-2.838,-2.365,-0.473,,0.669,E,B,0.48,-0.14,3.946,,73.78,BHH,-2.337,0.361275,0.00403589,0.642013 kka2_1:1_A65Q,kka2_1:1_65,Kka2,kka2_1:1,P00552,0.642056,NO,65,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.744,-2.822,1.078,,0.437,H,A,0.46,-0.39,3.012,,63.64,HHB,-1.38733,0.520039,0.00709258,0.642056 beta-lactamase_0_R176W,beta-lactamase_0_176,TEM-1,beta-lactamase_0,P62593,0.642058,NO,176,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-0.863,-5.322,4.459,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.0500837,0.00105554,0.642058 kka2_1:2_L174T,kka2_1:2_174,Kka2,kka2_1:2,P00552,0.642092,NO,174,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.952,-3.474,2.522,,,H,A,1.59,-0.31,8.521,,51.89,BHB,-2.08533,0.295029,0.00438501,0.642092 kka2_1:8_D90Y,kka2_1:8_90,Kka2,kka2_1:8,P00552,0.642104,NO,90,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.459,-3.217,0.758,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.100394,0.00583842,0.642104 kka2_1:8_D90Y,kka2_1:8_90,Kka2,kka2_1:8,P00552,0.642104,NO,90,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.459,-3.217,0.758,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.100394,0.00583842,0.642104 kka2_1:4_W15T,kka2_1:4_15,Kka2,kka2_1:4,P00552,0.642164,NO,15,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-1.392,-3.666,2.274,,0.01,G,A,0.47,0.15,0.943,,52.27,HHH,-2.10533,0.168804,0.00585505,0.642164 Pab1_T145D,Pab1_145,Pab1,Pab1,P04147,0.642174,NO,145,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.067,-3.286,2.219,,0.237,H,A,0.3,0.69,,,,APH,-1.135,0.175299,0.000331088,0.642174 kka2_1:1_A41E,kka2_1:1_41,Kka2,kka2_1:1,P00552,0.642252,NO,41,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.879,-3.093,1.214,,0.184,.,B,0.46,-0.96,18.207,18.207,64.39,PHP,-2.477,0.520039,0.00543332,0.642252 beta-lactamase_2500_G236N,beta-lactamase_2500_236,TEM-1,beta-lactamase_2500,P62593,0.642259,NO,236,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.784,-3.509,2.725,,0.241,,b,0.29,-0.59,2.14,,64.69,HOO,-1.025,0.361275,0.00162372,0.642259 kka2_1:4_E262G,kka2_1:4_262,Kka2,kka2_1:4,P00552,0.642298,NO,262,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-0.829,-3.41,2.581,,0.059,G,A,1.04,-0.18,2.383,,42.42,AAH,-0.816,0.168804,0.0191586,0.642298 beta-lactamase_V117A,beta-lactamase_117,TEM-1,beta-lactamase,P62593,0.642412,NO,117,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.53,-3.142,1.612,5.33594,,H,A,1.19,-0.34,1.182,,65.03,PHB,-1.741,0.221079,0.00467906,0.642412 beta-lactamase_R159G,beta-lactamase_159,TEM-1,beta-lactamase,P62593,0.642431,NO,159,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-0.94,-3.384,2.444,5.64971,0.316,,B,0.68,-0.55,1.172,,64.34,PBH,-1.011,0.221079,0.00108472,0.642431 beta-lactamase_156_G114I,beta-lactamase_156_114,TEM-1,beta-lactamase_156,P62593,0.642579,NO,114,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.094,-4.083,2.989,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.111618,0.00224919,0.642579 beta-lactamase_0_G265K,beta-lactamase_0_265,TEM-1,beta-lactamase_0,P62593,0.642623,NO,265,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.0500837,0.00811926,0.642623 beta-lactamase_2500_L188A,beta-lactamase_2500_188,TEM-1,beta-lactamase_2500,P62593,0.642644,NO,188,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.166,-2.542,1.376,,,H,A,0.55,-0.3,17.865,17.865,60.14,PHB,-1.47033,0.361275,0.00295687,0.642644 kka2_1:2_A191P,kka2_1:2_191,Kka2,kka2_1:2,P00552,0.642644,NO,191,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.831,-2.353,1.522,,,.,b,0.46,-0.94,2.046,,50,AHO,-0.868667,0.295029,0.00338807,0.642644 beta-lactamase_D231C,beta-lactamase_231,TEM-1,beta-lactamase,P62593,0.64265,NO,231,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.816,-5.136,4.32,5.06651,,E,B,1.22,-1.06,0.319,,65.38,HAB,-0.994,0.221079,0.00107395,0.64265 beta-lactamase_S264Y,beta-lactamase_264,TEM-1,beta-lactamase,P62593,0.642663,NO,264,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.985,-4.246,2.261,4.67475,0.04,,B,0.25,0.29,34.251,34.251,73.78,OPP,-2.19867,0.221079,0.0119399,0.642663 kka2_1:2_S104I,kka2_1:2_104,Kka2,kka2_1:2,P00552,0.642792,NO,104,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.436,-3.864,2.428,,0.536,T,A,0.27,-1.11,5.49,,63.64,HPP,-1.91433,0.295029,0.00555207,0.642792 kka2_1:4_S104V,kka2_1:4_104,Kka2,kka2_1:4,P00552,0.642832,NO,104,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.436,-2.726,1.29,,0.536,T,A,0.27,-1.11,0.357,,63.64,HPP,-1.91433,0.168804,0.00555207,0.642832 beta-lactamase_2500_S104N,beta-lactamase_2500_104,TEM-1,beta-lactamase_2500,P62593,0.642877,NO,104,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.015,-3.421,2.406,,0.04,,b,0.27,0.57,1.133,,63.29,HPO,-1.05267,0.361275,0.00218083,0.642877 WW_domain_G185A,WW_domain_185,Yap65,WW_domain,P46937,0.642995,NO,185,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.861,-2.63,1.769,6.22337,,,,,,,,,POP,-1.194,0.153962,0.00199178,0.642995 kka2_1:1_V80P,kka2_1:1_80,Kka2,kka2_1:1,P00552,0.643059,NO,80,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.144,-2.863,1.719,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.520039,0.00488211,0.643059 beta-lactamase_156_A133P,beta-lactamase_156_133,TEM-1,beta-lactamase_156,P62593,0.643314,NO,133,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.186,-3.811,2.625,,,H,A,0.46,-0.86,0.805,,67.83,HHP,-0.988333,0.111618,0.00468022,0.643314 Pab1_A179N,Pab1_179,Pab1,Pab1,P04147,0.64333,NO,179,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.013,-3.715,2.702,,0.078,H,A,0.61,0.5,,,,HHB,-1.51233,0.175299,0.000291703,0.64333 kka2_1:1_E230A,kka2_1:1_230,Kka2,kka2_1:1,P00552,0.643335,NO,230,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.672,-2.43,-0.242,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.520039,0.00920051,0.643335 beta-lactamase_0_L120C,beta-lactamase_0_120,TEM-1,beta-lactamase_0,P62593,0.643355,NO,120,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.044,-4.81,3.766,,,H,A,0.55,-1.13,1.2,,64.69,AHO,-1.13633,0.0500837,0.00143563,0.643355 kka2_1:8_C192D,kka2_1:8_192,Kka2,kka2_1:8,P00552,0.643372,NO,192,C,D,CD,Special,negativeCharge,5.07,5.0516,-0.0184,154,121,133,12,108.5,111.1,2.6,-1.067,-3.871,2.804,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.100394,0.00485428,0.643372 kka2_1:8_C192D,kka2_1:8_192,Kka2,kka2_1:8,P00552,0.643372,NO,192,C,D,CD,Special,negativeCharge,5.07,5.0516,-0.0184,154,121,133,12,108.5,111.1,2.6,-1.067,-3.871,2.804,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.100394,0.00485428,0.643372 kka2_1:1_L39P,kka2_1:1_39,Kka2,kka2_1:1,P00552,0.643412,NO,39,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.223,-4.188,2.965,,,E,B,0.55,-1.21,0.925,,71.59,BHP,-1.69167,0.520039,0.00493618,0.643412 kka2_1:4_F48W,kka2_1:4_48,Kka2,kka2_1:4,P00552,0.643453,NO,48,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.453,-4.763,3.31,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.168804,0.00475422,0.643453 beta-lactamase_625_G141F,beta-lactamase_625_141,TEM-1,beta-lactamase_625,P62593,0.643456,NO,141,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.828,-4.352,3.524,,0.575,T,l,0.29,-0.28,0.198,,64.69,HOO,-1.08933,0.213352,0.0012419,0.643456 kka2_1:2_T225S,kka2_1:2_225,Kka2,kka2_1:2,P00552,0.643505,NO,225,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.393,-2.531,0.138,,0.036,H,A,0.22,-1.22,4.554,,63.64,HPB,-1.58733,0.295029,0.0113598,0.643505 beta-lactamase_0_T139I,beta-lactamase_0_139,TEM-1,beta-lactamase_0,P62593,0.643542,NO,139,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.901,-3.075,1.174,,0.216,H,A,0.22,0.39,0.421,,77.62,PPH,-2.04667,0.0500837,0.00441837,0.643542 beta-lactamase_D231T,beta-lactamase_231,TEM-1,beta-lactamase,P62593,0.643636,NO,231,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.816,-3.447,2.631,5.06651,,E,B,1.22,-1.06,0.319,,65.38,HAB,-0.994,0.221079,0.00107395,0.643636 kka2_1:1_L243V,kka2_1:1_243,Kka2,kka2_1:1,P00552,0.64372,NO,243,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-2.651,-2.869,0.218,,0.277,H,A,0.55,-0.67,4.334,,92.05,HHH,-2.03767,0.520039,0.00884927,0.64372 kka2_1:1_L47M,kka2_1:1_47,Kka2,kka2_1:1,P00552,0.643731,NO,47,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.265,-4.186,2.921,,0.139,E,B,0.55,-0.86,14.593,14.593,63.26,HHH,-1.77933,0.520039,0.00509386,0.643731 kka2_1:2_Y218S,kka2_1:2_218,Kka2,kka2_1:2,P00552,0.643731,NO,218,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-1.438,-3.656,2.218,,0.122,H,A,0.21,-0.69,1.022,,56.06,BHP,-1.17533,0.295029,0.0126098,0.643731 kka2_1:1_R217L,kka2_1:1_217,Kka2,kka2_1:1,P00552,0.64375,NO,217,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.158,-2.651,1.493,,0.252,T,A,1.2,-0.59,0.381,,52.27,ABH,-1.127,0.520039,0.0047191,0.64375 kka2_1:2_E182G,kka2_1:2_182,Kka2,kka2_1:2,P00552,0.6438,NO,182,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.516,-2.588,1.072,,0.326,,B,1.52,0.75,14.547,14.547,65.53,OAA,-1.806,0.295029,0.00641548,0.6438 kka2_1:4_F48S,kka2_1:4_48,Kka2,kka2_1:4,P00552,0.643843,NO,48,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.453,-3.787,2.334,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.168804,0.00475422,0.643843 beta-lactamase_625_L219D,beta-lactamase_625_219,TEM-1,beta-lactamase_625,P62593,0.64393,NO,219,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.313,-4.126,2.813,,,I,A,0.55,-0.51,5.627,,74.48,HHB,-1.21533,0.213352,0.00664345,0.64393 kka2_1:1_A119E,kka2_1:1_119,Kka2,kka2_1:1,P00552,0.643932,NO,119,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.073,-3.557,2.484,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.520039,0.00441074,0.643932 beta-lactamase_2500_D48A,beta-lactamase_2500_48,TEM-1,beta-lactamase_2500,P62593,0.644014,NO,48,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.101,-2.565,1.464,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.361275,0.0027273,0.644014 kka2_1:2_K112Q,kka2_1:2_112,Kka2,kka2_1:2,P00552,0.644015,NO,112,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-2.491,-2.826,0.335,,0.076,H,A,2.34,-1.37,23.433,23.433,56.06,ABH,-2.00133,0.295029,0.00645389,0.644015 beta-lactamase_625_D231E,beta-lactamase_625_231,TEM-1,beta-lactamase_625,P62593,0.644097,NO,231,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.816,-2.232,1.416,,,E,B,0.75,-1.06,1.025,,65.38,HAB,-0.994,0.213352,0.00107395,0.644097 beta-lactamase_0_G76I,beta-lactamase_0_76,TEM-1,beta-lactamase_0,P62593,0.644123,NO,76,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.189,-3.948,2.759,,,H,A,0.29,-0.67,1.188,,67.83,OOH,-1.22267,0.0500837,0.00476637,0.644123 kka2_1:2_D227Y,kka2_1:2_227,Kka2,kka2_1:2,P00552,0.644275,NO,227,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.758,-4.295,2.537,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.295029,0.00745029,0.644275 kka2_1:1_G10R,kka2_1:1_10,Kka2,kka2_1:1,P00552,0.644315,NO,10,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.921,-2.648,0.727,,,,,,,1.862,,71.59,HOP,-2.10733,0.520039,0.00289233,0.644315 kka2_1:1_G43C,kka2_1:1_43,Kka2,kka2_1:1,P00552,0.644448,NO,43,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.587,-3.529,1.942,,0.862,T,l,0.75,-0.67,2.247,,63.26,POB,-2.18533,0.520039,0.0071925,0.644448 kka2_1:1_D134N,kka2_1:1_134,Kka2,kka2_1:1,P00552,0.6445,NO,134,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.969,-2.658,1.689,,0.421,B,B,0.75,0.31,2.329,,49.62,HAB,-1.057,0.520039,0.00270812,0.6445 beta-lactamase_L137E,beta-lactamase_137,TEM-1,beta-lactamase,P62593,0.644517,NO,137,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.03,-3.919,2.889,5.20117,,H,A,1.07,-0.38,0.674,,42.31,HHP,-1.58933,0.221079,0.00278599,0.644517 kka2_1:4_G30V,kka2_1:4_30,Kka2,kka2_1:4,P00552,0.644655,NO,30,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.596,-3.782,3.186,,0.54,S,g,0.29,3.76,,,,HOO,-1.51133,0.168804,0.00159208,0.644655 kka2_1:1_R177K,kka2_1:1_177,Kka2,kka2_1:1,P00552,0.64474,NO,177,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.282,-3.03,0.748,,0.521,T,A,1.2,0.16,1.842,,63.64,HBH,-2.36967,0.520039,0.00768224,0.64474 kka2_1:2_R121Q,kka2_1:2_121,Kka2,kka2_1:2,P00552,0.644768,NO,121,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.552,-2.59,1.038,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.295029,0.00523326,0.644768 beta-lactamase_V78F,beta-lactamase_78,TEM-1,beta-lactamase,P62593,0.644774,NO,78,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.459,-3.883,2.424,4.79197,,H,A,0.96,-0.47,1.132,,63.64,HHH,-1.17833,0.221079,0.00492501,0.644774 beta-lactamase_2500_P250C,beta-lactamase_2500_250,TEM-1,beta-lactamase_2500,P62593,0.644784,NO,250,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.361275,0.00550899,0.644784 beta-lactamase_0_P165N,beta-lactamase_0_165,TEM-1,beta-lactamase_0,P62593,0.644806,NO,165,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.373,-3.703,2.33,,0.203,T,A,0.52,-0.31,3.242,,73.78,AOA,-1.359,0.0500837,0.00549538,0.644806 beta-lactamase_0_V82Y,beta-lactamase_0_82,TEM-1,beta-lactamase_0,P62593,0.644935,NO,82,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.325,-4.133,2.808,,0.267,H,A,0.44,0.08,1.893,,93.01,BHA,-1.28567,0.0500837,0.00397046,0.644935 beta-lactamase_G154F,beta-lactamase_154,TEM-1,beta-lactamase,P62593,0.645001,NO,154,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.823,-4.328,3.505,5.40944,0.54,T,l,0.77,-0.56,2.283,,64.69,HOA,-1.635,0.221079,0.00180205,0.645001 beta-lactamase_0_D83F,beta-lactamase_0_83,TEM-1,beta-lactamase_0,P62593,0.645016,NO,83,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.066,-4.344,3.278,,0.354,H,A,0.75,0.22,0.617,,48.95,HAH,-1.34733,0.0500837,0.00205968,0.645016 beta-lactamase_156_G281E,beta-lactamase_156_281,TEM-1,beta-lactamase_156,P62593,0.64506,NO,281,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.111618,0.0406482,0.64506 kka2_1:2_D127Q,kka2_1:2_127,Kka2,kka2_1:2,P00552,0.645083,NO,127,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.364,-3.882,2.518,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.295029,0.00660501,0.645083 kka2_1:1_A117S,kka2_1:1_117,Kka2,kka2_1:1,P00552,0.645122,NO,117,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.828,-3.072,2.244,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.520039,0.00282984,0.645122 Ubiquitin_N60E,Ubiquitin_60,Uba1,Ubiquitin,P0CG48,0.645161,NO,60,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-1.775,-2.803,1.028,5.00332,0.775,T,L,,0.33,,,,HPH,-1.532,0.205827,0.000814061,0.645161 Ubiquitin_R42A,Ubiquitin_42,Uba1,Ubiquitin,P0CG48,0.645161,NO,42,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.571,-3.162,1.591,5.07805,0.244,E,B,0.68,-0.54,1.976,,72.85,PBH,-1.38967,0.205827,0.000622265,0.645161 kka2_1:1_A168T,kka2_1:1_168,Kka2,kka2_1:1,P00552,0.645164,NO,168,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.989,-2.711,0.722,,0.67,H,A,0.46,0.15,25.546,25.546,64.39,OHA,-2.12933,0.520039,0.00806773,0.645164 kka2_1:4_W236Y,kka2_1:4_236,Kka2,kka2_1:4,P00552,0.645187,NO,236,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-1.363,-2.865,1.502,,0.303,H,A,0.47,-0.76,2.277,,48.48,AHH,-1.81267,0.168804,0.0088796,0.645187 kka2_1:8_C209P,kka2_1:8_209,Kka2,kka2_1:8,P00552,0.645228,NO,209,C,P,CP,Special,Special,5.07,6.3,1.23,169,121,115,-6,108.5,112.7,4.2,-0.906,-4.156,3.25,,,,a,1.5,-0.89,0.391,,19.32,AOO,-0.903,0.100394,0.00260862,0.645228 kka2_1:8_C209P,kka2_1:8_209,Kka2,kka2_1:8,P00552,0.645228,NO,209,C,P,CP,Special,Special,5.07,6.3,1.23,169,121,115,-6,108.5,112.7,4.2,-0.906,-4.156,3.25,,,,a,1.5,-0.89,0.391,,19.32,AOO,-0.903,0.100394,0.00260862,0.645228 kka2_1:4_L260V,kka2_1:4_260,Kka2,kka2_1:4,P00552,0.645232,NO,260,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.741,-2.882,2.141,,0.022,H,A,0.55,-0.52,,,,HHA,-0.845667,0.168804,0.0233782,0.645232 beta-lactamase_156_A124Q,beta-lactamase_156_124,TEM-1,beta-lactamase_156,P62593,0.645306,NO,124,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.181,-4.004,2.823,,,H,A,0.46,-0.9,2.027,,64.34,HHH,-1.152,0.111618,0.00481399,0.645306 kka2_1:2_I221S,kka2_1:2_221,Kka2,kka2_1:2,P00552,0.645439,NO,221,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.739,-3.764,2.025,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.295029,0.00945908,0.645439 beta-lactamase_0_T186Y,beta-lactamase_0_186,TEM-1,beta-lactamase_0,P62593,0.645449,NO,186,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.522,-4.364,1.842,,0.396,H,A,0.22,-0.28,16.606,16.606,77.62,HPP,-1.77633,0.0500837,0.00485034,0.645449 beta-lactamase_156_R59F,beta-lactamase_156_59,TEM-1,beta-lactamase_156,P62593,0.645536,NO,59,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.345,-4.379,3.034,,0.329,S,L,1.2,-0.09,2.995,,73.08,HBO,-2.24267,0.111618,0.00318082,0.645536 kka2_1:1_D157G,kka2_1:1_157,Kka2,kka2_1:1,P00552,0.645616,NO,157,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.993,-2.513,1.52,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.520039,0.0042313,0.645616 WW_domain_Q186N,WW_domain_186,Yap65,WW_domain,P46937,0.645709,NO,186,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-1.358,-3.225,1.867,4.88854,,,,,,,,,OPB,-1.207,0.153962,0.00161546,0.645709 beta-lactamase_G141L,beta-lactamase_141,TEM-1,beta-lactamase,P62593,0.645767,NO,141,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.828,-3.844,3.016,5.03155,0.575,T,l,0.76,-0.28,0.198,,64.69,HOO,-1.08933,0.221079,0.0012419,0.645767 beta-lactamase_0_G265Y,beta-lactamase_0_265,TEM-1,beta-lactamase_0,P62593,0.645865,NO,265,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.0500837,0.00811926,0.645865 kka2_1:8_A237N,kka2_1:8_237,Kka2,kka2_1:8,P00552,0.645925,NO,237,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.12,-4.131,2.011,,0.068,H,A,0.46,-0.71,0.449,,92.05,HHA,-2.10433,0.100394,0.012257,0.645925 kka2_1:8_A237N,kka2_1:8_237,Kka2,kka2_1:8,P00552,0.645925,NO,237,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.12,-4.131,2.011,,0.068,H,A,0.46,-0.71,0.449,,92.05,HHA,-2.10433,0.100394,0.012257,0.645925 kka2_1:2_D127H,kka2_1:2_127,Kka2,kka2_1:2,P00552,0.645992,NO,127,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.364,-4.683,3.319,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.295029,0.00660501,0.645992 beta-lactamase_625_A123I,beta-lactamase_625_123,TEM-1,beta-lactamase_625,P62593,0.646018,NO,123,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.834,-3.433,2.599,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.213352,0.0010157,0.646018 kka2_1:1_R239H,kka2_1:1_239,Kka2,kka2_1:1,P00552,0.646071,NO,239,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.949,-2.896,-0.053,,0.15,H,A,1.2,-0.31,0.477,,71.59,ABH,-2.23,0.520039,0.00835326,0.646071 kka2_1:4_G181P,kka2_1:4_181,Kka2,kka2_1:4,P00552,0.646078,NO,181,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-2.698,-3.097,0.399,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.168804,0.00728319,0.646078 kka2_1:1_L123V,kka2_1:1_123,Kka2,kka2_1:1,P00552,0.646089,NO,123,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.888,-2.888,2,,0.007,H,A,0.55,-0.4,1.447,,48.86,BHB,-1.301,0.520039,0.00325188,0.646089 beta-lactamase_39_Y44S,beta-lactamase_39_44,TEM-1,beta-lactamase_39,P62593,0.646108,NO,44,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-2.547,-3.605,1.058,,,E,B,0.21,-0.45,2.683,,73.78,OHH,-1.86267,0.0495842,0.00426364,0.646108 kka2_1:4_A150I,kka2_1:4_150,Kka2,kka2_1:4,P00552,0.646167,NO,150,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.949,-3.788,2.839,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.168804,0.0045009,0.646167 kka2_1:1_E17R,kka2_1:1_17,Kka2,kka2_1:1,P00552,0.646191,NO,17,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.154,-2.815,0.661,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.520039,0.00688738,0.646191 beta-lactamase_0_D174M,beta-lactamase_0_174,TEM-1,beta-lactamase_0,P62593,0.646195,NO,174,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.738,-4.93,4.192,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.0500837,0.00125633,0.646195 kka2_1:4_V186L,kka2_1:4_186,Kka2,kka2_1:4,P00552,0.64625,NO,186,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.011,-2.323,1.312,,,E,B,0.44,-0.61,0.679,,45.83,HHP,-1.10967,0.168804,0.00409703,0.64625 beta-lactamase_2500_L135F,beta-lactamase_2500_135,TEM-1,beta-lactamase_2500,P62593,0.646262,NO,135,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.002,-3.671,2.669,,0.117,H,A,0.55,-0.58,0.795,,43.71,PHH,-1.03767,0.361275,0.00244423,0.646262 gb1_Y229N,gb1_229,gb1,gb1,P06654,0.646281,NO,229,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-1.282,-3.633,2.351,,,,,,,,,,PHB,-1.4915,0.177985,0.00366605,0.646281 Pab1_L153P,Pab1_153,Pab1,Pab1,P04147,0.646282,NO,153,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.039,-3.922,2.883,,0.46,E,A,,-0.95,,,,HHP,-1.17667,0.175299,0.000321212,0.646282 kka2_1:2_A25W,kka2_1:2_25,Kka2,kka2_1:2,P00552,0.646341,NO,25,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.496,-5.529,3.033,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.295029,0.00595636,0.646341 kka2_1:2_G189V,kka2_1:2_189,Kka2,kka2_1:2,P00552,0.64635,NO,189,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.596,-3.782,3.186,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.295029,0.00253688,0.64635 kka2_1:4_G189C,kka2_1:4_189,Kka2,kka2_1:4,P00552,0.646475,NO,189,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.596,-5.115,4.519,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.168804,0.00253688,0.646475 kka2_1:8_P194L,kka2_1:8_194,Kka2,kka2_1:8,P00552,0.646666,NO,194,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.846,-3.652,2.806,,0.308,G,A,0.52,-1.19,4.861,,53.03,HOP,-0.888333,0.100394,0.00314194,0.646666 kka2_1:8_P194L,kka2_1:8_194,Kka2,kka2_1:8,P00552,0.646666,NO,194,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.846,-3.652,2.806,,0.308,G,A,0.52,-1.19,4.861,,53.03,HOP,-0.888333,0.100394,0.00314194,0.646666 kka2_1:8_V36R,kka2_1:8_36,Kka2,kka2_1:8,P00552,0.646714,NO,36,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-0.898,-4.231,3.333,,0.292,E,B,1.48,0.21,0.938,,52.27,HHH,-1.484,0.100394,0.00245633,0.646714 kka2_1:8_V36R,kka2_1:8_36,Kka2,kka2_1:8,P00552,0.646714,NO,36,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-0.898,-4.231,3.333,,0.292,E,B,1.48,0.21,0.938,,52.27,HHH,-1.484,0.100394,0.00245633,0.646714 beta-lactamase_2500_L135Q,beta-lactamase_2500_135,TEM-1,beta-lactamase_2500,P62593,0.646757,NO,135,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.002,-4.162,3.16,,0.117,H,A,0.55,-0.58,0.795,,43.71,PHH,-1.03767,0.361275,0.00244423,0.646757 beta-lactamase_L100A,beta-lactamase_100,TEM-1,beta-lactamase,P62593,0.646778,NO,100,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.218,-3.158,1.94,5.60291,0.343,,B,1.3,0.13,1.173,,63.29,AHH,-1.23467,0.221079,0.00413885,0.646778 kka2_1:2_R122C,kka2_1:2_122,Kka2,kka2_1:2,P00552,0.646922,NO,122,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.175,-5.179,3.004,,0.487,H,A,1.2,0.26,16.436,16.436,71.59,BBH,-1.53833,0.295029,0.00736512,0.646922 kka2_1:2_F48V,kka2_1:2_48,Kka2,kka2_1:2,P00552,0.646934,NO,48,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.453,-2.048,0.595,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.295029,0.00475422,0.646934 kka2_1:8_L70I,kka2_1:8_70,Kka2,kka2_1:8,P00552,0.647051,NO,70,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.017,-2.539,1.522,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.100394,0.00411884,0.647051 kka2_1:8_L70I,kka2_1:8_70,Kka2,kka2_1:8,P00552,0.647051,NO,70,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.017,-2.539,1.522,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.100394,0.00411884,0.647051 beta-lactamase_625_S266E,beta-lactamase_625_266,TEM-1,beta-lactamase_625,P62593,0.647124,NO,266,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.213352,0.0140785,0.647124 beta-lactamase_I259Y,beta-lactamase_259,TEM-1,beta-lactamase,P62593,0.64714,NO,259,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.522,-4.12,2.598,5.28457,,E,B,1,-0.8,1.24,,64.34,HHH,-1.53267,0.221079,0.0070773,0.64714 WW_domain_G185L,WW_domain_185,Yap65,WW_domain,P46937,0.647267,NO,185,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.861,-3.585,2.724,6.22337,,,,,,,,,POP,-1.194,0.153962,0.00199178,0.647267 kka2_1:1_A65S,kka2_1:1_65,Kka2,kka2_1:1,P00552,0.64733,NO,65,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.744,-2.937,1.193,,0.437,H,A,0.46,-0.39,3.012,,63.64,HHB,-1.38733,0.520039,0.00709258,0.64733 kka2_1:1_E231Y,kka2_1:1_231,Kka2,kka2_1:1,P00552,0.647334,NO,231,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.002,-4.332,2.33,,0.503,H,A,1.04,-0.23,25.629,25.629,63.26,AAH,-2.06267,0.520039,0.00732383,0.647334 kka2_1:2_D190E,kka2_1:2_190,Kka2,kka2_1:2,P00552,0.647394,NO,190,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.708,-2.793,2.085,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.295029,0.00247989,0.647394 beta-lactamase_0_A282N,beta-lactamase_0_282,TEM-1,beta-lactamase_0,P62593,0.647457,NO,282,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.0500837,0.0449821,0.647457 beta-lactamase_0_V42Y,beta-lactamase_0_42,TEM-1,beta-lactamase_0,P62593,0.647521,NO,42,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.564,-4.12,2.556,,0.017,E,B,0.44,-0.51,1.659,,63.99,BHO,-1.042,0.0500837,0.00404515,0.647521 beta-lactamase_0_Q276F,beta-lactamase_0_276,TEM-1,beta-lactamase_0,P62593,0.647522,NO,276,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.0500837,0.0191712,0.647522 kka2_1:1_V80L,kka2_1:1_80,Kka2,kka2_1:1,P00552,0.647536,NO,80,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.144,-2.831,1.687,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.520039,0.00488211,0.647536 beta-lactamase_625_P143L,beta-lactamase_625_143,TEM-1,beta-lactamase_625,P62593,0.647559,NO,143,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.967,-2.577,1.61,,0.075,H,A,0.52,-0.37,1.445,,66.78,OOB,-1.354,0.213352,0.00114551,0.647559 kka2_1:1_R38G,kka2_1:1_38,Kka2,kka2_1:1,P00552,0.64762,NO,38,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.207,-3.596,2.389,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.520039,0.00372499,0.64762 kka2_1:2_D157C,kka2_1:2_157,Kka2,kka2_1:2,P00552,0.647623,NO,157,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.993,-5.181,4.188,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.295029,0.0042313,0.647623 kka2_1:2_E199W,kka2_1:2_199,Kka2,kka2_1:2,P00552,0.647649,NO,199,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.234,-3.699,1.465,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.295029,0.00854122,0.647649 beta-lactamase_0_Y95E,beta-lactamase_0_95,TEM-1,beta-lactamase_0,P62593,0.647681,NO,95,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-1.715,-3.911,2.196,,0.122,,b,0.21,-0.37,2.914,,77.62,BHP,-2.16167,0.0500837,0.00479449,0.647681 beta-lactamase_625_L137N,beta-lactamase_625_137,TEM-1,beta-lactamase_625,P62593,0.647686,NO,137,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.03,-4.152,3.122,,,H,A,0.55,-0.38,1.5,,42.31,HHP,-1.58933,0.213352,0.00278599,0.647686 gb1_V255P,gb1_255,gb1,gb1,P06654,0.647724,NO,255,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-3.127,-3.672,0.545,,,,,,,1.323,,45.54,BHH,-2.03867,0.177985,0.00408354,0.647724 beta-lactamase_2500_M184L,beta-lactamase_2500_184,TEM-1,beta-lactamase_2500,P62593,0.647865,NO,184,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.593,-2.806,1.213,,,H,A,0.55,-0.87,2.893,,62.94,HHH,-1.41,0.361275,0.00356019,0.647865 beta-lactamase_0_R59G,beta-lactamase_0_59,TEM-1,beta-lactamase_0,P62593,0.647943,NO,59,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.345,-3.412,2.067,,0.329,S,L,1.2,-0.09,2.919,,73.08,HBO,-2.24267,0.0500837,0.00318082,0.647943 Pab1_F168R,Pab1_168,Pab1,Pab1,P04147,0.64804,NO,168,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.269,-3.969,2.7,,,,,,,0.789,,56.33,OHO,-1.10033,0.175299,0.00064061,0.64804 kka2_1:4_D154E,kka2_1:4_154,Kka2,kka2_1:4,P00552,0.64812,NO,154,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.876,-2.369,1.493,,0.457,,b,0.29,1.48,15.641,15.641,52.65,HAP,-1.52467,0.168804,0.00292633,0.64812 beta-lactamase_A123I,beta-lactamase_123,TEM-1,beta-lactamase,P62593,0.648175,NO,123,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.834,-3.433,2.599,4.70061,0.039,H,A,0.52,-0.72,0.705,,41.26,PHH,-1.47367,0.221079,0.0010157,0.648175 beta-lactamase_R220A,beta-lactamase_220,TEM-1,beta-lactamase,P62593,0.648208,NO,220,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-0.942,-2.357,1.415,5.65995,0.295,I,A,0.68,-0.76,2.164,,74.48,HBP,-1.33633,0.221079,0.00232421,0.648208 kka2_1:1_A222C,kka2_1:1_222,Kka2,kka2_1:1,P00552,0.648231,NO,222,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.725,-4.44,3.715,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.520039,0.00207657,0.648231 beta-lactamase_2500_A222D,beta-lactamase_2500_222,TEM-1,beta-lactamase_2500,P62593,0.648237,NO,222,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.103,-3.723,1.62,,0.233,H,A,0.46,-0.25,0.379,,77.62,PHH,-1.63733,0.361275,0.00466094,0.648237 kka2_1:2_H135N,kka2_1:2_135,Kka2,kka2_1:2,P00552,0.64829,NO,135,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-1.331,-3.533,2.202,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.295029,0.00532566,0.64829 kka2_1:4_L243G,kka2_1:4_243,Kka2,kka2_1:4,P00552,0.64832,NO,243,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-2.651,-3.604,0.953,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.168804,0.00884927,0.64832 kka2_1:4_V113A,kka2_1:4_113,Kka2,kka2_1:4,P00552,0.648322,NO,113,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.233,-2.573,1.34,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.168804,0.00650191,0.648322 kka2_1:4_V214C,kka2_1:4_214,Kka2,kka2_1:4,P00552,0.648334,NO,214,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.261,-3.243,1.982,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.168804,0.00692782,0.648334 beta-lactamase_P65V,beta-lactamase_65,TEM-1,beta-lactamase,P62593,0.648343,NO,65,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.894,-3.39,2.496,5.59094,0.098,E,B,0.23,-0.62,0.623,,40.56,HOH,-1.03233,0.221079,0.00152776,0.648343 kka2_1:1_A172K,kka2_1:1_172,Kka2,kka2_1:1,P00552,0.64838,NO,172,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.757,-3.042,1.285,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.520039,0.0079265,0.64838 beta-lactamase_39_T107E,beta-lactamase_39_107,TEM-1,beta-lactamase_39,P62593,0.648401,NO,107,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.117,-3.43,2.313,,,G,A,0.22,-0.06,2.686,,67.83,HPA,-1.265,0.0495842,0.00239347,0.648401 beta-lactamase_A40H,beta-lactamase_40,TEM-1,beta-lactamase,P62593,0.648407,NO,40,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.402,-4.792,3.39,4.9697,0.155,S,B,1.2,0.21,1.714,,73.78,OHB,-1.40267,0.221079,0.00490026,0.648407 kka2_1:1_A176R,kka2_1:1_176,Kka2,kka2_1:1,P00552,0.648523,NO,176,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.621,-2.52,0.899,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.520039,0.0083587,0.648523 kka2_1:4_I115A,kka2_1:4_115,Kka2,kka2_1:4,P00552,0.648526,NO,115,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.606,-2.706,1.1,,0.105,H,A,1.52,-1.18,9.996,9.996,65.53,PHH,-2.205,0.168804,0.00836567,0.648526 kka2_1:2_Y244T,kka2_1:2_244,Kka2,kka2_1:2,P00552,0.648546,NO,244,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-0.775,-3.675,2.9,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.295029,0.00453187,0.648546 kka2_1:1_A172R,kka2_1:1_172,Kka2,kka2_1:1,P00552,0.648549,NO,172,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.757,-2.665,0.908,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.520039,0.0079265,0.648549 kka2_1:8_T85R,kka2_1:8_85,Kka2,kka2_1:8,P00552,0.648581,NO,85,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.165,-2.814,0.649,,0.576,E,B,0.22,1.39,22.154,22.154,71.59,HPA,-2.10133,0.100394,0.00634493,0.648581 kka2_1:8_T85R,kka2_1:8_85,Kka2,kka2_1:8,P00552,0.648581,NO,85,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.165,-2.814,0.649,,0.576,E,B,0.22,1.39,22.154,22.154,71.59,HPA,-2.10133,0.100394,0.00634493,0.648581 kka2_1:8_A215R,kka2_1:8_215,Kka2,kka2_1:8,P00552,0.648588,NO,215,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.968,-3.821,2.853,,0.039,E,B,1.04,-0.59,2.77,,50.38,HHA,-1.00467,0.100394,0.00529129,0.648588 kka2_1:8_A215R,kka2_1:8_215,Kka2,kka2_1:8,P00552,0.648588,NO,215,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.968,-3.821,2.853,,0.039,E,B,1.04,-0.59,2.77,,50.38,HHA,-1.00467,0.100394,0.00529129,0.648588 beta-lactamase_N134H,beta-lactamase_134,TEM-1,beta-lactamase,P62593,0.648611,NO,134,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-0.879,-4.073,3.194,5.07245,0.138,H,A,0.09,-0.6,1.441,,53.15,HPH,-1.02233,0.221079,0.000644786,0.648611 PSD95pdz3_K393P,PSD95pdz3_393,PSD95pdz3,PSD95pdz3,P31016,0.648653,NO,393,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.416,-3.336,1.92,5.42682,,,,,22.0122,,,,HBO,-1.4265,0.0758425,0.000879298,0.648653 kka2_1:1_P12R,kka2_1:1_12,Kka2,kka2_1:1,P00552,0.648908,NO,12,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.853,-3.931,3.078,,,.,B,0.52,1.25,0.261,,48.11,POH,-1.80767,0.520039,0.00500011,0.648908 beta-lactamase_P65H,beta-lactamase_65,TEM-1,beta-lactamase,P62593,0.648932,NO,65,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.894,-4.735,3.841,5.59094,0.098,E,B,0.23,-0.62,0.623,,40.56,HOH,-1.03233,0.221079,0.00152776,0.648932 beta-lactamase_R59M,beta-lactamase_59,TEM-1,beta-lactamase,P62593,0.64895,NO,59,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.345,-4.605,3.26,5.49837,0.329,S,L,0.68,-0.09,1.806,,73.08,HBO,-2.24267,0.221079,0.00318082,0.64895 beta-lactamase_2500_R159F,beta-lactamase_2500_159,TEM-1,beta-lactamase_2500,P62593,0.649006,NO,159,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-0.94,-4.255,3.315,,0.316,,B,1.2,-0.55,2.341,,64.34,PBH,-1.011,0.361275,0.00108472,0.649006 kka2_1:8_V198R,kka2_1:8_198,Kka2,kka2_1:8,P00552,0.649019,NO,198,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.719,-3.986,2.267,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.100394,0.00835002,0.649019 kka2_1:8_V198R,kka2_1:8_198,Kka2,kka2_1:8,P00552,0.649019,NO,198,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.719,-3.986,2.267,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.100394,0.00835002,0.649019 beta-lactamase_G263V,beta-lactamase_263,TEM-1,beta-lactamase,P62593,0.649034,NO,263,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-2.031,-3.684,1.653,5.09799,0.517,S,l,0.77,0.31,16.425,16.425,77.62,POP,-1.78267,0.221079,0.0110582,0.649034 beta-lactamase_156_T178D,beta-lactamase_156_178,TEM-1,beta-lactamase_156,P62593,0.64908,NO,178,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-0.791,-3.469,2.678,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.111618,0.000684366,0.64908 kka2_1:1_H106Q,kka2_1:1_106,Kka2,kka2_1:1,P00552,0.649118,NO,106,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-3.13,-3.142,0.012,,1.065,.,a,0.17,-0.95,2.53,,71.59,PBH,-2.10433,0.520039,0.00730778,0.649118 beta-lactamase_2500_L100W,beta-lactamase_2500_100,TEM-1,beta-lactamase_2500,P62593,0.649128,NO,100,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.218,-5.168,3.95,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.361275,0.00413885,0.649128 kka2_1:1_M178T,kka2_1:1_178,Kka2,kka2_1:1,P00552,0.649135,NO,178,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-3.206,-3.644,0.438,,0.554,.,b,0.55,0.68,3.152,,71.59,BHO,-2.154,0.520039,0.00717253,0.649135 gb1_G235E,gb1_235,gb1,gb1,P06654,0.649154,NO,235,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.419,-3.357,1.938,,,,,,,0.476,,11.83,POB,-1.86433,0.177985,0.00297491,0.649154 beta-lactamase_39_L79R,beta-lactamase_39_79,TEM-1,beta-lactamase_39,P62593,0.649243,NO,79,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.842,-3.93,3.088,,0.007,H,A,0.55,-0.16,0.823,,50.35,HHP,-1.44333,0.0495842,0.000947397,0.649243 beta-lactamase_D174M,beta-lactamase_174,TEM-1,beta-lactamase,P62593,0.649249,NO,174,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.738,-4.93,4.192,5.44133,0.238,,B,1.22,-0.1,,,,PAA,-1.91233,0.221079,0.00125633,0.649249 kka2_1:2_N200L,kka2_1:2_200,Kka2,kka2_1:2,P00552,0.649293,NO,200,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-2.446,-3.814,1.368,,0.756,T,L,0.61,-0.08,2.836,,64.39,APO,-2.08,0.295029,0.00838549,0.649293 kka2_1:2_S105I,kka2_1:2_105,Kka2,kka2_1:2,P00552,0.64935,NO,105,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.945,-3.89,1.945,,0.056,S,B,0.27,-1.04,3.442,,65.53,PPB,-2.17033,0.295029,0.00847233,0.64935 PSD95pdz3_V362R,PSD95pdz3_362,PSD95pdz3,PSD95pdz3,P31016,0.649363,NO,362,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.465,-3.84,2.375,4.99436,,,,,19.6443,,,,PHP,-1.46467,0.0758425,0.000538527,0.649363 kka2_1:2_R143F,kka2_1:2_143,Kka2,kka2_1:2,P00552,0.64943,NO,143,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.525,-4.3,1.775,,0.325,H,A,0.16,1.22,14.853,14.853,65.53,ABH,-1.86833,0.295029,0.00662247,0.64943 kka2_1:4_F171V,kka2_1:4_171,Kka2,kka2_1:4,P00552,0.649568,NO,171,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.326,-3.284,1.958,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.168804,0.00821426,0.649568 beta-lactamase_625_L218C,beta-lactamase_625_218,TEM-1,beta-lactamase_625,P62593,0.64958,NO,218,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.391,-4.928,3.537,,,I,b,0.55,-0.53,17.202,17.202,74.48,OHH,-1.58867,0.213352,0.00618274,0.64958 kka2_1:4_C209R,kka2_1:4_209,Kka2,kka2_1:4,P00552,0.64968,NO,209,C,R,CR,Special,PositiveCharge,5.07,6.34148,1.27148,180,121,174,53,108.5,173.4,64.9,-0.906,-4.184,3.278,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.168804,0.00260862,0.64968 beta-lactamase_N134K,beta-lactamase_134,TEM-1,beta-lactamase,P62593,0.649721,NO,134,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-0.879,-2.445,1.566,5.07245,0.138,H,A,0.09,-0.6,1.441,,53.15,HPH,-1.02233,0.221079,0.000644786,0.649721 beta-lactamase_L49K,beta-lactamase_49,TEM-1,beta-lactamase,P62593,0.649743,NO,49,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.897,-3.583,1.686,5.86005,0.131,T,A,1.3,0.04,3.112,,64.69,AHP,-1.99233,0.221079,0.00401477,0.649743 kka2_1:4_T225R,kka2_1:4_225,Kka2,kka2_1:4,P00552,0.649749,NO,225,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.393,-4.06,1.667,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.168804,0.0113598,0.649749 kka2_1:4_R121Q,kka2_1:4_121,Kka2,kka2_1:4,P00552,0.649759,NO,121,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.552,-2.59,1.038,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.168804,0.00523326,0.649759 kka2_1:2_R226L,kka2_1:2_226,Kka2,kka2_1:2,P00552,0.649775,NO,226,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.392,-3.592,2.2,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.295029,0.0108032,0.649775 Pab1_G126D,Pab1_126,Pab1,Pab1,P04147,0.649798,NO,126,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.985,-3.389,2.404,,0.011,T,A,0.46,-0.07,2.349,,80.42,OOP,-1.032,0.175299,0.00109814,0.649798 kka2_1:1_A35K,kka2_1:1_35,Kka2,kka2_1:1,P00552,0.64985,NO,35,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.127,-3.623,1.496,,0.107,E,B,0.46,1.05,8.405,8.405,71.59,HHH,-1.31767,0.520039,0.00630016,0.64985 hsp90_F583D,hsp90_583,hsp90,hsp90,P02829,0.649879,NO,583,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-3.22,-2.847,0,5.28185,1.112,S,l,1.1,0.87,,,,PHO,-3.003,0.368192,0.000222939,0.649879 kka2_1:4_A71D,kka2_1:4_71,Kka2,kka2_1:4,P00552,0.649897,NO,71,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.824,-3.702,1.878,,0.553,H,A,0.46,0.08,5.76,,64.39,HHP,-1.74033,0.168804,0.00727707,0.649897 beta-lactamase_625_D161Y,beta-lactamase_625_161,TEM-1,beta-lactamase_625,P62593,0.649927,NO,161,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.891,-4.387,3.496,,0.341,,A,0.75,-0.52,4.655,,61.19,HAB,-0.961333,0.213352,0.000897697,0.649927 kka2_1:2_E182H,kka2_1:2_182,Kka2,kka2_1:2,P00552,0.649941,NO,182,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.516,-2.568,1.052,,0.326,,B,1.52,0.75,14.547,14.547,65.53,OAA,-1.806,0.295029,0.00641548,0.649941 beta-lactamase_625_W288H,beta-lactamase_625_288,TEM-1,beta-lactamase_625,P62593,0.649962,NO,288,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,,,,,,,,,,,,,BHO,,0.213352,,0.649962 kka2_1:1_E182A,kka2_1:1_182,Kka2,kka2_1:1,P00552,0.650131,NO,182,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.516,-2.542,1.026,,0.326,,B,1.52,0.75,14.547,14.547,65.53,OAA,-1.806,0.520039,0.00641548,0.650131 kka2_1:8_K112L,kka2_1:8_112,Kka2,kka2_1:8,P00552,0.65022,NO,112,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-2.491,-2.229,-0.262,,0.076,H,A,1.3,-1.37,10.58,10.58,56.06,ABH,-2.00133,0.100394,0.00645389,0.65022 kka2_1:8_K112L,kka2_1:8_112,Kka2,kka2_1:8,P00552,0.65022,NO,112,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-2.491,-2.229,-0.262,,0.076,H,A,1.3,-1.37,10.58,10.58,56.06,ABH,-2.00133,0.100394,0.00645389,0.65022 kka2_1:8_A117Y,kka2_1:8_117,Kka2,kka2_1:8,P00552,0.650244,NO,117,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.828,-4.189,3.361,,,H,A,1.04,-0.78,0.755,,45.83,HHA,-1.79333,0.100394,0.00282984,0.650244 kka2_1:8_A117Y,kka2_1:8_117,Kka2,kka2_1:8,P00552,0.650244,NO,117,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.828,-4.189,3.361,,,H,A,1.04,-0.78,0.755,,45.83,HHA,-1.79333,0.100394,0.00282984,0.650244 Pab1_G126V,Pab1_126,Pab1,Pab1,P04147,0.650272,NO,126,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.985,-3.413,2.428,,0.011,T,A,0.46,-0.07,2.349,,80.42,OOP,-1.032,0.175299,0.00109814,0.650272 kka2_1:4_Y244I,kka2_1:4_244,Kka2,kka2_1:4,P00552,0.6503,NO,244,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-0.775,-3.589,2.814,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.168804,0.00453187,0.6503 kka2_1:1_E230G,kka2_1:1_230,Kka2,kka2_1:1,P00552,0.650306,NO,230,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.672,-3.574,0.902,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.520039,0.00920051,0.650306 beta-lactamase_0_T69Q,beta-lactamase_0_69,TEM-1,beta-lactamase_0,P62593,0.650355,NO,69,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-0.973,-3.935,2.962,,,G,A,0.22,-1.24,0.505,,93.01,PPH,-1.01833,0.0500837,0.00127498,0.650355 PSD95pdz3_L323T,PSD95pdz3_323,PSD95pdz3,PSD95pdz3,P31016,0.650392,NO,323,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.347,-3.103,1.756,5.12397,,,,,13.8825,,,,OHO,-1.121,0.0758425,0.00104644,0.650392 beta-lactamase_2500_E46F,beta-lactamase_2500_46,TEM-1,beta-lactamase_2500,P62593,0.650629,NO,46,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.94,-4.056,2.116,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.361275,0.00427568,0.650629 E1_Ubiquitin_G47C,E1_Ubiquitin_47,Uba1,E1_Ubiquitin,P0CG63,0.650752,NO,47,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.999,-4.958,3.959,,0.057,T,l,,-1.21,,,,HOB,-1.195,0.18783,0.00142261,0.650752 kka2_1:2_G201V,kka2_1:2_201,Kka2,kka2_1:2,P00552,0.650759,NO,201,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.56,-3.892,2.332,,0.149,T,l,0.29,-0.57,16.092,16.092,52.65,POB,-1.92233,0.295029,0.00820117,0.650759 beta-lactamase_R59C,beta-lactamase_59,TEM-1,beta-lactamase,P62593,0.650905,NO,59,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.345,-2.854,1.509,5.49837,0.329,S,L,0.68,-0.09,1.806,,73.08,HBO,-2.24267,0.221079,0.00318082,0.650905 beta-lactamase_R91C,beta-lactamase_91,TEM-1,beta-lactamase,P62593,0.650917,NO,91,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.392,-5.127,3.735,5.92536,0.444,,B,0.68,0.96,1.318,,50.35,OBB,-1.73367,0.221079,0.00380226,0.650917 beta-lactamase_625_L100S,beta-lactamase_625_100,TEM-1,beta-lactamase_625,P62593,0.651015,NO,100,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.218,-3.715,2.497,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.213352,0.00413885,0.651015 kka2_1:8_A117H,kka2_1:8_117,Kka2,kka2_1:8,P00552,0.651023,NO,117,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.828,-4.772,3.944,,,H,A,1.04,-0.78,0.755,,45.83,HHA,-1.79333,0.100394,0.00282984,0.651023 kka2_1:8_A117H,kka2_1:8_117,Kka2,kka2_1:8,P00552,0.651023,NO,117,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.828,-4.772,3.944,,,H,A,1.04,-0.78,0.755,,45.83,HHA,-1.79333,0.100394,0.00282984,0.651023 kka2_1:2_H188D,kka2_1:2_188,Kka2,kka2_1:2,P00552,0.651045,NO,188,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-0.913,-3.495,2.582,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.295029,0.00273139,0.651045 kka2_1:1_L259M,kka2_1:1_259,Kka2,kka2_1:1,P00552,0.651064,NO,259,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.088,-2.71,1.622,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.520039,0.0206964,0.651064 kka2_1:8_A191V,kka2_1:8_191,Kka2,kka2_1:8,P00552,0.651118,NO,191,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.831,-3.195,2.364,,,,b,1.04,-0.94,1.306,,50,AHO,-0.868667,0.100394,0.00338807,0.651118 kka2_1:8_A191V,kka2_1:8_191,Kka2,kka2_1:8,P00552,0.651118,NO,191,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.831,-3.195,2.364,,,,b,1.04,-0.94,1.306,,50,AHO,-0.868667,0.100394,0.00338807,0.651118 beta-lactamase_2500_Y95V,beta-lactamase_2500_95,TEM-1,beta-lactamase_2500,P62593,0.651161,NO,95,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-1.715,-2.446,0.731,,0.122,,b,0.21,-0.37,2.914,,77.62,BHP,-2.16167,0.361275,0.00479449,0.651161 beta-lactamase_M67F,beta-lactamase_67,TEM-1,beta-lactamase,P62593,0.651166,NO,67,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-2.231,-4.128,1.897,4.9618,0.006,G,P,1.07,-0.81,1.463,,65.03,HHP,-1.502,0.221079,0.00409753,0.651166 beta-lactamase_2500_G194W,beta-lactamase_2500_194,TEM-1,beta-lactamase_2500,P62593,0.651269,NO,194,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.396,-5.42,4.024,,0.276,S,b,0.29,0.36,3.593,,67.83,POA,-1.832,0.361275,0.00392163,0.651269 beta-lactamase_0_D271K,beta-lactamase_0_271,TEM-1,beta-lactamase_0,P62593,0.651291,NO,271,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.0500837,0.00752082,0.651291 beta-lactamase_D231M,beta-lactamase_231,TEM-1,beta-lactamase,P62593,0.651371,NO,231,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.816,-4.927,4.111,5.06651,,E,B,1.22,-1.06,0.319,,65.38,HAB,-0.994,0.221079,0.00107395,0.651371 beta-lactamase_2500_E56H,beta-lactamase_2500_56,TEM-1,beta-lactamase_2500,P62593,0.651401,NO,56,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.043,-4.467,2.424,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.361275,0.00238534,0.651401 kka2_1:1_M178I,kka2_1:1_178,Kka2,kka2_1:1,P00552,0.651484,NO,178,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-3.206,-2.948,-0.258,,0.554,.,b,0.55,0.68,3.152,,71.59,BHO,-2.154,0.520039,0.00717253,0.651484 beta-lactamase_M184Q,beta-lactamase_184,TEM-1,beta-lactamase,P62593,0.651665,NO,184,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.593,-3.011,1.418,5.39575,,H,A,1.3,-0.87,2.893,,62.94,HHH,-1.41,0.221079,0.00356019,0.651665 beta-lactamase_S51I,beta-lactamase_51,TEM-1,beta-lactamase,P62593,0.651665,NO,51,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.526,-3.925,2.399,5.06164,0.496,T,A,0.25,0.26,1.699,,72.73,PPO,-1.88467,0.221079,0.00504821,0.651665 beta-lactamase_39_V31Q,beta-lactamase_39_31,TEM-1,beta-lactamase_39,P62593,0.651704,NO,31,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.822,-4.296,2.474,,,H,A,0.44,-0.46,2.885,,73.78,BHB,-2.03767,0.0495842,0.00478065,0.651704 beta-lactamase_625_E119C,beta-lactamase_625_119,TEM-1,beta-lactamase_625,P62593,0.651708,NO,119,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.412,-5.165,3.753,,0.358,H,A,1.04,0.51,1.034,,63.99,BAH,-1.623,0.213352,0.00386966,0.651708 beta-lactamase_0_L218F,beta-lactamase_0_218,TEM-1,beta-lactamase_0,P62593,0.651762,NO,218,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.391,-2.985,1.594,,,I,b,0.55,-0.53,28.707,28.707,74.48,OHH,-1.58867,0.0500837,0.00618274,0.651762 kka2_1:1_R89S,kka2_1:1_89,Kka2,kka2_1:1,P00552,0.651799,NO,89,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.548,-3.512,1.964,,0.209,E,B,0.16,1.41,14.396,14.396,64.39,OBA,-1.89867,0.520039,0.00524373,0.651799 beta-lactamase_2500_E87Q,beta-lactamase_2500_87,TEM-1,beta-lactamase_2500,P62593,0.651866,NO,87,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.421,-2.648,1.227,,0.048,,B,1.04,0.92,17.923,17.923,64.69,PAP,-1.969,0.361275,0.00337888,0.651866 kka2_1:1_T72P,kka2_1:1_72,Kka2,kka2_1:1,P00552,0.651946,NO,72,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.38,-4.008,1.628,,0.784,H,A,0.22,0.29,10.43,10.43,65.53,HPP,-2.238,0.520039,0.00750756,0.651946 beta-lactamase_0_L89P,beta-lactamase_0_89,TEM-1,beta-lactamase_0,P62593,0.651947,NO,89,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.096,-2.221,1.125,,0.168,T,A,0.55,0.63,2.373,,64.34,PHO,-1.75767,0.0500837,0.00207068,0.651947 kka2_1:2_A224S,kka2_1:2_224,Kka2,kka2_1:2,P00552,0.652006,NO,224,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.977,-3.088,2.111,,,H,A,0.46,-1.26,1.646,,63.64,HHP,-1.41033,0.295029,0.00352047,0.652006 PSD95pdz3_A375H,PSD95pdz3_375,PSD95pdz3,PSD95pdz3,P31016,0.652006,NO,375,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.307,-4.362,3.055,5.05512,,,,,13.888,,,,PHH,-1.43767,0.0758425,0.000356809,0.652006 kka2_1:4_P109C,kka2_1:4_109,Kka2,kka2_1:4,P00552,0.65211,NO,109,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.412,-5.056,3.644,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.168804,0.0070929,0.65211 WW_domain_G176A,WW_domain_176,Yap65,WW_domain,P46937,0.652117,NO,176,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.235,-1.983,0.748,6.33142,,,,,,2.71,,78.57,HOH,-1.35467,0.153962,0.00288552,0.652117 kka2_1:1_H188C,kka2_1:1_188,Kka2,kka2_1:1,P00552,0.652127,NO,188,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-0.913,-5.139,4.226,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.520039,0.00273139,0.652127 kka2_1:2_A41Y,kka2_1:2_41,Kka2,kka2_1:2,P00552,0.652259,NO,41,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.879,-4.263,2.384,,0.184,.,B,0.46,-0.96,24.451,24.451,64.39,PHP,-2.477,0.295029,0.00543332,0.652259 PSD95pdz3_G324M,PSD95pdz3_324,PSD95pdz3,PSD95pdz3,P31016,0.652274,NO,324,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.008,-4.612,3.604,4.98881,,,,,10.4525,,,,HOH,-1.293,0.0758425,0.00103462,0.652274 beta-lactamase_L160P,beta-lactamase_160,TEM-1,beta-lactamase,P62593,0.652303,NO,160,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.977,-4.121,3.144,5.32068,0.022,,B,1.75,-0.6,0.895,,44.41,BHA,-0.936,0.221079,0.00193775,0.652303 Pab1_F168I,Pab1_168,Pab1,Pab1,P04147,0.652342,NO,168,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.269,-3.256,1.987,,,,,,,0.789,,56.33,OHO,-1.10033,0.175299,0.00064061,0.652342 beta-lactamase_2500_G141Q,beta-lactamase_2500_141,TEM-1,beta-lactamase_2500,P62593,0.652359,NO,141,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.828,-3.982,3.154,,0.575,T,l,0.29,-0.28,1.493,,64.69,HOO,-1.08933,0.361275,0.0012419,0.652359 beta-lactamase_625_P65H,beta-lactamase_625_65,TEM-1,beta-lactamase_625,P62593,0.652384,NO,65,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.894,-4.735,3.841,,0.098,E,B,0.52,-0.62,0.3,,40.56,HOH,-1.03233,0.213352,0.00152776,0.652384 beta-lactamase_0_P181M,beta-lactamase_0_181,TEM-1,beta-lactamase_0,P62593,0.652385,NO,181,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.813,-4.702,3.889,,,H,A,0.52,-1.14,1.357,,61.54,HOH,-1.795,0.0500837,0.000703122,0.652385 kka2_1:1_V242L,kka2_1:1_242,Kka2,kka2_1:1,P00552,0.652439,NO,242,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-2.687,-3.55,0.863,,0.75,H,A,0.44,-0.37,4.987,,71.59,HHH,-2.16533,0.520039,0.0102575,0.652439 kka2_1:8_L126E,kka2_1:8_126,Kka2,kka2_1:8,P00552,0.652452,NO,126,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.246,-3.857,2.611,,0.285,S,B,1.59,0.12,4.443,,51.89,PHA,-1.744,0.100394,0.0066485,0.652452 kka2_1:8_L126E,kka2_1:8_126,Kka2,kka2_1:8,P00552,0.652452,NO,126,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.246,-3.857,2.611,,0.285,S,B,1.59,0.12,4.443,,51.89,PHA,-1.744,0.100394,0.0066485,0.652452 beta-lactamase_0_F228N,beta-lactamase_0_228,TEM-1,beta-lactamase_0,P62593,0.652485,NO,228,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-2.342,-3.038,0.696,,0.154,E,B,0.58,-0.42,15.504,15.504,63.29,HHH,-1.53033,0.0500837,0.0046669,0.652485 kka2_1:8_L170R,kka2_1:8_170,Kka2,kka2_1:8,P00552,0.652541,NO,170,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.28,-4.103,2.823,,0.029,H,A,1.59,0.11,1.453,,62.5,AHH,-1.534,0.100394,0.00730791,0.652541 kka2_1:8_L170R,kka2_1:8_170,Kka2,kka2_1:8,P00552,0.652541,NO,170,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.28,-4.103,2.823,,0.029,H,A,1.59,0.11,1.453,,62.5,AHH,-1.534,0.100394,0.00730791,0.652541 beta-lactamase_L47K,beta-lactamase_47,TEM-1,beta-lactamase,P62593,0.652642,NO,47,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.876,-3.656,1.78,5.27297,0.007,E,B,1.07,0.2,1.244,,67.83,AHA,-1.639,0.221079,0.00439844,0.652642 kka2_1:8_Y257C,kka2_1:8_257,Kka2,kka2_1:8,P00552,0.652683,NO,257,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-1.064,-4.949,3.885,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.100394,0.0148191,0.652683 kka2_1:8_Y257C,kka2_1:8_257,Kka2,kka2_1:8,P00552,0.652683,NO,257,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-1.064,-4.949,3.885,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.100394,0.0148191,0.652683 beta-lactamase_2500_P165A,beta-lactamase_2500_165,TEM-1,beta-lactamase_2500,P62593,0.652757,NO,165,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.373,-3.022,1.649,,0.203,T,A,0.52,-0.31,0.414,,73.78,AOA,-1.359,0.361275,0.00549538,0.652757 kka2_1:2_D52Y,kka2_1:2_52,Kka2,kka2_1:2,P00552,0.652795,NO,52,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.271,-4.235,1.964,,0.22,E,B,0.75,0.8,1.123,,71.59,PAH,-2.38367,0.295029,0.00175694,0.652795 kka2_1:1_K112R,kka2_1:1_112,Kka2,kka2_1:1,P00552,0.652904,NO,112,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-2.491,-2.2,-0.291,,0.076,H,A,2.34,-1.37,23.433,23.433,56.06,ABH,-2.00133,0.520039,0.00645389,0.652904 beta-lactamase_39_I125G,beta-lactamase_39_125,TEM-1,beta-lactamase_39,P62593,0.652999,NO,125,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.441,-3.768,2.327,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.0495842,0.00383964,0.652999 kka2_1:8_L19G,kka2_1:8_19,Kka2,kka2_1:8,P00552,0.653061,NO,19,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.254,-3.863,2.609,,0.08,T,A,1.59,-0.26,2.044,,65.53,BHH,-2.221,0.100394,0.00620703,0.653061 kka2_1:8_L19G,kka2_1:8_19,Kka2,kka2_1:8,P00552,0.653061,NO,19,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.254,-3.863,2.609,,0.08,T,A,1.59,-0.26,2.044,,65.53,BHH,-2.221,0.100394,0.00620703,0.653061 kka2_1:8_L70R,kka2_1:8_70,Kka2,kka2_1:8,P00552,0.653126,NO,70,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.017,-4.037,3.02,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.100394,0.00411884,0.653126 kka2_1:8_L70R,kka2_1:8_70,Kka2,kka2_1:8,P00552,0.653126,NO,70,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.017,-4.037,3.02,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.100394,0.00411884,0.653126 beta-lactamase_2500_G43A,beta-lactamase_2500_43,TEM-1,beta-lactamase_2500,P62593,0.653214,NO,43,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.62,-2.853,2.233,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.361275,0.00120151,0.653214 Ubiquitin_A28P,Ubiquitin_28,Uba1,Ubiquitin,P0CG48,0.653226,NO,28,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.895,-2.987,1.092,4.73736,0.369,H,A,,-0.11,,,,BHB,-1.47667,0.205827,0.000842053,0.653226 Ubiquitin_K27S,Ubiquitin_27,Uba1,Ubiquitin,P0CG48,0.653226,NO,27,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.064,-3.187,2.123,4.77438,0.086,H,A,2.89,-0.74,2.662,,27.01,HBH,-1.42667,0.205827,0.000767556,0.653226 Ubiquitin_L67E,Ubiquitin_67,Uba1,Ubiquitin,P0CG48,0.653226,NO,67,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.435,-3.685,2.25,4.92156,,E,B,1.19,-1.02,6.371,6.371,30.8,PHB,-1.628,0.205827,0.000482727,0.653226 Ubiquitin_L71F,Ubiquitin_71,Uba1,Ubiquitin,P0CG48,0.653226,NO,71,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.647,-2.531,0.884,5.02588,0.591,E,B,2.89,-0.69,4.365,,34.31,HHB,-1.85167,0.205827,0.000949314,0.653226 kka2_1:2_D82A,kka2_1:2_82,Kka2,kka2_1:2,P00552,0.653227,NO,82,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.946,-1.898,-0.048,,0.341,E,b,0.75,0.52,11.923,11.923,63.64,HAH,-1.98,0.295029,0.00637516,0.653227 beta-lactamase_39_G236R,beta-lactamase_39_236,TEM-1,beta-lactamase_39,P62593,0.653278,NO,236,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.784,-3.932,3.148,,0.241,,b,0.29,-0.59,1.883,,64.69,HOO,-1.025,0.0495842,0.00162372,0.653278 beta-lactamase_G141V,beta-lactamase_141,TEM-1,beta-lactamase,P62593,0.653294,NO,141,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.828,-3.79,2.962,5.03155,0.575,T,l,0.76,-0.28,0.198,,64.69,HOO,-1.08933,0.221079,0.0012419,0.653294 beta-lactamase_2500_C75T,beta-lactamase_2500_75,TEM-1,beta-lactamase_2500,P62593,0.653314,NO,75,C,T,CT,Special,Polar,5.07,5.6,0.53,149,121,119,-2,108.5,116.1,7.6,-1.245,-3.423,2.178,,,H,A,0.46,-0.87,0.844,,50,HOO,-1.24333,0.361275,0.0034616,0.653314 beta-lactamase_0_L47K,beta-lactamase_0_47,TEM-1,beta-lactamase_0,P62593,0.65333,NO,47,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.876,-3.656,1.78,,0.007,E,B,0.55,0.2,1.024,,67.83,AHA,-1.639,0.0500837,0.00439844,0.65333 beta-lactamase_625_T158G,beta-lactamase_625_158,TEM-1,beta-lactamase_625,P62593,0.653387,NO,158,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.116,-3.288,2.172,,0.036,,B,0.22,-0.85,3.771,,69.58,HPB,-1.269,0.213352,0.00341825,0.653387 kka2_1:4_C192A,kka2_1:4_192,Kka2,kka2_1:4,P00552,0.653417,NO,192,C,A,CA,Special,Hydrophobic,5.07,6,0.93,195,121,89,-32,108.5,88.6,-19.9,-1.067,-2.954,1.887,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.168804,0.00485428,0.653417 kka2_1:1_N200D,kka2_1:1_200,Kka2,kka2_1:1,P00552,0.653424,NO,200,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-2.446,-2.235,-0.211,,0.756,T,L,0.61,-0.08,17.299,17.299,64.39,APO,-2.08,0.520039,0.00838549,0.653424 beta-lactamase_R91W,beta-lactamase_91,TEM-1,beta-lactamase,P62593,0.653453,NO,91,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.392,-5.388,3.996,5.92536,0.444,,B,0.68,0.96,1.318,,50.35,OBB,-1.73367,0.221079,0.00380226,0.653453 kka2_1:2_L243T,kka2_1:2_243,Kka2,kka2_1:2,P00552,0.653453,NO,243,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-2.651,-2.872,0.221,,0.277,H,A,1.59,-0.67,13.165,13.165,92.05,HHH,-2.03767,0.295029,0.00884927,0.653453 kka2_1:4_A172P,kka2_1:4_172,Kka2,kka2_1:4,P00552,0.653643,NO,172,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.757,-4.041,2.284,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.168804,0.0079265,0.653643 kka2_1:1_G151R,kka2_1:1_151,Kka2,kka2_1:1,P00552,0.653651,NO,151,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.873,-2.905,2.032,,0.678,T,l,0.29,1.36,0.226,,49.62,HOH,-1.11433,0.520039,0.00339918,0.653651 beta-lactamase_R241Q,beta-lactamase_241,TEM-1,beta-lactamase,P62593,0.653676,NO,241,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.433,-3.733,2.3,5.02621,0.094,E,B,0.68,-0.16,1.327,,50,PBO,-1.42967,0.221079,0.00452736,0.653676 kka2_1:1_L232M,kka2_1:1_232,Kka2,kka2_1:1,P00552,0.653752,NO,232,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.514,-4.338,2.824,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.520039,0.00800103,0.653752 kka2_1:1_E230H,kka2_1:1_230,Kka2,kka2_1:1,P00552,0.653757,NO,230,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.672,-2.411,-0.261,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.520039,0.00920051,0.653757 kka2_1:4_V198F,kka2_1:4_198,Kka2,kka2_1:4,P00552,0.653791,NO,198,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.719,-4.163,2.444,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.168804,0.00835002,0.653791 beta-lactamase_625_S201F,beta-lactamase_625_201,TEM-1,beta-lactamase_625,P62593,0.653798,NO,201,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.183,-4.138,2.955,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.213352,0.00198815,0.653798 beta-lactamase_625_L218V,beta-lactamase_625_218,TEM-1,beta-lactamase_625,P62593,0.653842,NO,218,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.391,-3.3,1.909,,,I,b,0.55,-0.53,17.202,17.202,74.48,OHH,-1.58867,0.213352,0.00618274,0.653842 beta-lactamase_2500_R176F,beta-lactamase_2500_176,TEM-1,beta-lactamase_2500,P62593,0.654092,NO,176,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-0.863,-4.292,3.429,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.361275,0.00105554,0.654092 beta-lactamase_L218V,beta-lactamase_218,TEM-1,beta-lactamase,P62593,0.654105,NO,218,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.391,-3.3,1.909,4.88972,,I,b,2.89,-0.53,12.788,12.788,74.48,OHH,-1.58867,0.221079,0.00618274,0.654105 kka2_1:2_V46K,kka2_1:2_46,Kka2,kka2_1:2,P00552,0.654228,NO,46,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-2.62,-3.127,0.507,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.295029,0.00631301,0.654228 beta-lactamase_156_Q203P,beta-lactamase_156_203,TEM-1,beta-lactamase_156,P62593,0.654239,NO,203,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.168,-3.941,1.773,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.111618,0.00631514,0.654239 Pab1_I137H,Pab1_137,Pab1,Pab1,P04147,0.654241,NO,137,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.212,-4.722,3.51,,0.068,,B,0.77,0.35,,,,AHA,-1.314,0.175299,0.000342224,0.654241 kka2_1:2_D118K,kka2_1:2_118,Kka2,kka2_1:2,P00552,0.654267,NO,118,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.07,-2.906,0.836,,0.61,H,A,0.75,-0.05,2.237,,64.39,HAH,-1.32367,0.295029,0.0067852,0.654267 E1_Ubiquitin_L43T,E1_Ubiquitin_43,Uba1,E1_Ubiquitin,P0CG63,0.654288,NO,43,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.188,-2.118,0.93,,,E,B,,-1.17,,,,BHH,-1.30733,0.18783,0.00190185,0.654288 beta-lactamase_0_D161C,beta-lactamase_0_161,TEM-1,beta-lactamase_0,P62593,0.654313,NO,161,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.891,-5.1,4.209,,0.341,,A,0.75,-0.52,0.795,,61.19,HAB,-0.961333,0.0500837,0.000897697,0.654313 beta-lactamase_39_G281K,beta-lactamase_39_281,TEM-1,beta-lactamase_39,P62593,0.654313,NO,281,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.0495842,0.0406482,0.654313 beta-lactamase_0_L284Y,beta-lactamase_0_284,TEM-1,beta-lactamase_0,P62593,0.654449,NO,284,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.981,,,,0.848,H,A,2.89,0.67,4.544,,77.62,PHH,-1.82133,0.0500837,0.0686156,0.654449 beta-lactamase_R271F,beta-lactamase_271,TEM-1,beta-lactamase,P62593,0.654506,NO,271,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.249,-4.211,2.962,5.24516,0.085,H,A,1.67,-0.05,0.474,,63.99,ABP,-1.36633,0.221079,0.00752082,0.654506 kka2_1:1_E17G,kka2_1:1_17,Kka2,kka2_1:1,P00552,0.654545,NO,17,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.154,-2.597,0.443,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.520039,0.00688738,0.654545 beta-lactamase_0_W288D,beta-lactamase_0_288,TEM-1,beta-lactamase_0,P62593,0.654571,NO,288,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,,,,,,,,,,,,,BHO,,0.0500837,,0.654571 beta-lactamase_156_T187R,beta-lactamase_156_187,TEM-1,beta-lactamase_156,P62593,0.654654,NO,187,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.401,-3.885,2.484,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.111618,0.00491782,0.654654 beta-lactamase_2500_S51R,beta-lactamase_2500_51,TEM-1,beta-lactamase_2500,P62593,0.654688,NO,51,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.526,-2.956,1.43,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.361275,0.00504821,0.654688 kka2_1:4_W236R,kka2_1:4_236,Kka2,kka2_1:4,P00552,0.654774,NO,236,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-1.363,-4.21,2.847,,0.303,H,A,0.47,-0.76,2.277,,48.48,AHH,-1.81267,0.168804,0.0088796,0.654774 PSD95pdz3_L323V,PSD95pdz3_323,PSD95pdz3,PSD95pdz3,P31016,0.65481,NO,323,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.347,-2.535,1.188,5.12397,,,,,13.8825,,,,OHO,-1.121,0.0758425,0.00104644,0.65481 beta-lactamase_156_W288R,beta-lactamase_156_288,TEM-1,beta-lactamase_156,P62593,0.654839,NO,288,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,,,,,,,,,,,,,BHO,,0.111618,,0.654839 Pab1_A199D,Pab1_199,Pab1,Pab1,P04147,0.655019,NO,199,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.53,-3.451,1.921,,,,,,,1.479,,80.42,HHO,-1.50467,0.175299,0.00145024,0.655019 kka2_1:1_H8W,kka2_1:1_8,Kka2,kka2_1:1,P00552,0.655045,NO,8,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-2.759,-5.188,2.429,,,,,,,16.971,16.971,71.59,HBH,-2.25467,0.520039,0.00256422,0.655045 kka2_1:2_R145L,kka2_1:2_145,Kka2,kka2_1:2,P00552,0.655199,NO,145,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.804,-3.61,1.806,,0.346,H,A,1.2,1.23,7.961,,63.64,HBP,-1.88033,0.295029,0.00846663,0.655199 kka2_1:8_L70P,kka2_1:8_70,Kka2,kka2_1:8,P00552,0.655228,NO,70,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.017,-4.164,3.147,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.100394,0.00411884,0.655228 kka2_1:8_L70P,kka2_1:8_70,Kka2,kka2_1:8,P00552,0.655228,NO,70,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.017,-4.164,3.147,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.100394,0.00411884,0.655228 kka2_1:2_L223M,kka2_1:2_223,Kka2,kka2_1:2,P00552,0.655272,NO,223,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.861,-3.916,3.055,,,H,A,0.55,-1.24,0.266,,50,HHH,-0.854333,0.295029,0.00253574,0.655272 beta-lactamase_2500_S241T,beta-lactamase_2500_241,TEM-1,beta-lactamase_2500,P62593,0.655278,NO,241,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.361275,0.00452736,0.655278 kka2_1:8_L102P,kka2_1:8_102,Kka2,kka2_1:8,P00552,0.655322,NO,102,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.804,-4.131,3.327,,,T,A,1.59,-1.17,0.97,,42.42,AHH,-1.398,0.100394,0.00201332,0.655322 kka2_1:8_L102P,kka2_1:8_102,Kka2,kka2_1:8,P00552,0.655322,NO,102,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.804,-4.131,3.327,,,T,A,1.59,-1.17,0.97,,42.42,AHH,-1.398,0.100394,0.00201332,0.655322 kka2_1:8_D101E,kka2_1:8_101,Kka2,kka2_1:8,P00552,0.655369,NO,101,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.028,-3.074,2.046,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.100394,0.00423361,0.655369 kka2_1:8_D101E,kka2_1:8_101,Kka2,kka2_1:8,P00552,0.655369,NO,101,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.028,-3.074,2.046,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.100394,0.00423361,0.655369 kka2_1:1_E230S,kka2_1:1_230,Kka2,kka2_1:1,P00552,0.655371,NO,230,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.672,-2.395,-0.277,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.520039,0.00920051,0.655371 kka2_1:2_E17F,kka2_1:2_17,Kka2,kka2_1:2,P00552,0.655557,NO,17,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.154,-4.494,2.34,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.295029,0.00688738,0.655557 kka2_1:2_L67P,kka2_1:2_67,Kka2,kka2_1:2,P00552,0.655581,NO,67,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.741,-4.133,3.392,,0.007,H,A,1.59,-0.66,,,,BHP,-1.42867,0.295029,0.00102787,0.655581 kka2_1:8_P132D,kka2_1:8_132,Kka2,kka2_1:8,P00552,0.655604,NO,132,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.775,-3.495,2.72,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.100394,0.0018489,0.655604 kka2_1:8_P132D,kka2_1:8_132,Kka2,kka2_1:8,P00552,0.655604,NO,132,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.775,-3.495,2.72,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.100394,0.0018489,0.655604 kka2_1:8_V186A,kka2_1:8_186,Kka2,kka2_1:8,P00552,0.655604,NO,186,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.011,-3.042,2.031,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.100394,0.00409703,0.655604 kka2_1:8_V186A,kka2_1:8_186,Kka2,kka2_1:8,P00552,0.655604,NO,186,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.011,-3.042,2.031,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.100394,0.00409703,0.655604 beta-lactamase_625_A132G,beta-lactamase_625_132,TEM-1,beta-lactamase_625,P62593,0.655628,NO,132,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.9,-3.009,2.109,,,H,A,0.46,-0.93,0.316,,64.69,PHH,-1.138,0.213352,0.000962524,0.655628 kka2_1:1_D159G,kka2_1:1_159,Kka2,kka2_1:1,P00552,0.655654,NO,159,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.82,-2.148,1.328,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.520039,0.0030485,0.655654 beta-lactamase_L191Q,beta-lactamase_191,TEM-1,beta-lactamase,P62593,0.655716,NO,191,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.087,-4.183,3.096,5.72226,,H,A,1.07,0.09,1.23,,63.29,BHH,-1.445,0.221079,0.00263549,0.655716 kka2_1:4_L39R,kka2_1:4_39,Kka2,kka2_1:4,P00552,0.655723,NO,39,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.223,-4.155,2.932,,,E,B,0.55,-1.21,1.998,,71.59,BHP,-1.69167,0.168804,0.00493618,0.655723 kka2_1:4_L70V,kka2_1:4_70,Kka2,kka2_1:4,P00552,0.65575,NO,70,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.017,-2.461,1.444,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.168804,0.00411884,0.65575 kka2_1:4_A215T,kka2_1:4_215,Kka2,kka2_1:4,P00552,0.6558,NO,215,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.968,-2.586,1.618,,0.039,E,B,0.46,-0.59,0.754,,50.38,HHA,-1.00467,0.168804,0.00529129,0.6558 kka2_1:1_S114K,kka2_1:1_114,Kka2,kka2_1:1,P00552,0.655825,NO,114,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.527,-3.596,1.069,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.520039,0.00705262,0.655825 beta-lactamase_0_F70L,beta-lactamase_0_70,TEM-1,beta-lactamase_0,P62593,0.655903,NO,70,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.169,-2.96,1.791,,,H,A,0.58,-1.34,2.153,,63.99,PHB,-0.980667,0.0500837,0.00193499,0.655903 kka2_1:4_G55E,kka2_1:4_55,Kka2,kka2_1:4,P00552,0.655942,NO,55,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.625,-2.785,1.16,,0.517,S,b,0.75,1.19,15.753,15.753,63.64,POH,-2.05967,0.168804,0.00667877,0.655942 E1_Ubiquitin_Q41K,E1_Ubiquitin_41,Uba1,E1_Ubiquitin,P0CG63,0.656057,NO,41,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-1.25,-2.824,1.574,,0.017,E,B,,-0.98,,,,PPB,-1.344,0.18783,0.00215097,0.656057 beta-lactamase_39_L192R,beta-lactamase_39_192,TEM-1,beta-lactamase_39,P62593,0.656094,NO,192,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.254,-4.095,2.841,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.0495842,0.00558728,0.656094 beta-lactamase_0_G141K,beta-lactamase_0_141,TEM-1,beta-lactamase_0,P62593,0.656104,NO,141,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.828,-3.62,2.792,,0.575,T,l,0.29,-0.28,0.722,,64.69,HOO,-1.08933,0.0500837,0.0012419,0.656104 PSD95pdz3_G330T,PSD95pdz3_330,PSD95pdz3,PSD95pdz3,P31016,0.656106,NO,330,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.008,-3.328,2.32,4.68351,,,,,31.405,,,,OOA,-1.14,0.0758425,0.000962386,0.656106 gb1_L233R,gb1_233,gb1,gb1,P06654,0.656121,NO,233,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-2.678,-3.587,0.909,,,,,,,0.822,,45.54,HHP,-2.30267,0.177985,0.00266958,0.656121 kka2_1:8_P45F,kka2_1:8_45,Kka2,kka2_1:8,P00552,0.656166,NO,45,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.774,-4.506,2.732,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.100394,0.00590481,0.656166 kka2_1:8_P45F,kka2_1:8_45,Kka2,kka2_1:8,P00552,0.656166,NO,45,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.774,-4.506,2.732,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.100394,0.00590481,0.656166 kka2_1:1_A14Q,kka2_1:1_14,Kka2,kka2_1:1,P00552,0.656205,NO,14,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.837,-2.773,0.936,,0.728,G,A,0.46,0.7,1.17,,71.59,HHH,-1.82567,0.520039,0.00706614,0.656205 beta-lactamase_0_L192D,beta-lactamase_0_192,TEM-1,beta-lactamase_0,P62593,0.656222,NO,192,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.254,-4.104,2.85,,0.095,H,A,0.55,0.35,1.756,,60.14,HHP,-1.41833,0.0500837,0.00558728,0.656222 kka2_1:2_L212V,kka2_1:2_212,Kka2,kka2_1:2,P00552,0.65626,NO,212,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.904,-2.413,1.509,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.295029,0.0031426,0.65626 kka2_1:8_G213R,kka2_1:8_213,Kka2,kka2_1:8,P00552,0.65626,NO,213,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.596,-3.961,3.365,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.100394,0.00187654,0.65626 kka2_1:8_G213R,kka2_1:8_213,Kka2,kka2_1:8,P00552,0.65626,NO,213,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.596,-3.961,3.365,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.100394,0.00187654,0.65626 kka2_1:4_W69F,kka2_1:4_69,Kka2,kka2_1:4,P00552,0.656301,NO,69,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-0.859,-3.388,2.529,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.168804,0.0012874,0.656301 kka2_1:8_H162I,kka2_1:8_162,Kka2,kka2_1:8,P00552,0.656337,NO,162,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-2.319,-4.138,1.819,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.100394,0.00616145,0.656337 kka2_1:8_H162I,kka2_1:8_162,Kka2,kka2_1:8,P00552,0.656337,NO,162,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-2.319,-4.138,1.819,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.100394,0.00616145,0.656337 PSD95pdz3_L367W,PSD95pdz3_367,PSD95pdz3,PSD95pdz3,P31016,0.656374,NO,367,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.347,-4.779,3.432,5.47696,,,,,17.0063,,,,AHB,-1.39767,0.0758425,0.000466436,0.656374 kka2_1:1_D23R,kka2_1:1_23,Kka2,kka2_1:1,P00552,0.656401,NO,23,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.459,-2.183,-0.276,,0.695,E,B,0.75,-0.65,2.655,,65.53,HAH,-1.94033,0.520039,0.007195,0.656401 WW_domain_G176P,WW_domain_176,Yap65,WW_domain,P46937,0.656402,NO,176,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.235,-3.713,2.478,6.33142,,,,,,2.71,,78.57,HOH,-1.35467,0.153962,0.00288552,0.656402 Pab1_N139R,Pab1_139,Pab1,Pab1,P04147,0.6565,NO,139,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-1.079,-3.3,2.221,,0.062,H,A,,-0.73,,,,APB,-1.09667,0.175299,0.000339145,0.6565 beta-lactamase_G279L,beta-lactamase_279,TEM-1,beta-lactamase,P62593,0.656552,NO,279,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.038,-3.6,2.562,4.53882,,H,A,0.46,-0.97,3.066,,62.59,HOH,-1.36467,0.221079,0.0192826,0.656552 kka2_1:2_G210S,kka2_1:2_210,Kka2,kka2_1:2,P00552,0.656686,NO,210,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.095,-1.997,0.902,,0.103,T,A,0.29,-0.62,0.271,,50,OOB,-0.966667,0.295029,0.00598378,0.656686 beta-lactamase_2500_V214K,beta-lactamase_2500_214,TEM-1,beta-lactamase_2500,P62593,0.656741,NO,214,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.299,-3.699,2.4,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.361275,0.00628442,0.656741 beta-lactamase_0_Q276K,beta-lactamase_0_276,TEM-1,beta-lactamase_0,P62593,0.656811,NO,276,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.0500837,0.0191712,0.656811 kka2_1:8_E59K,kka2_1:8_59,Kka2,kka2_1:8,P00552,0.656821,NO,59,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-0.952,-3.163,2.211,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.100394,0.00280355,0.656821 kka2_1:8_E59K,kka2_1:8_59,Kka2,kka2_1:8,P00552,0.656821,NO,59,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-0.952,-3.163,2.211,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.100394,0.00280355,0.656821 beta-lactamase_0_L55D,beta-lactamase_0_55,TEM-1,beta-lactamase_0,P62593,0.656882,NO,55,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.86,-4.094,2.234,,0.372,E,A,0.55,-0.36,1.967,,63.99,HHA,-2.247,0.0500837,0.00403741,0.656882 kka2_1:4_H135A,kka2_1:4_135,Kka2,kka2_1:4,P00552,0.656899,NO,135,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-1.331,-2.452,1.121,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.168804,0.00532566,0.656899 PSD95pdz3_H372Q,PSD95pdz3_372,PSD95pdz3,PSD95pdz3,P31016,0.65691,NO,372,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-1.627,-3.356,1.729,5.5607,,,,,17.008,,,,PBA,-1.63033,0.0758425,0.00040301,0.65691 Pab1_F168C,Pab1_168,Pab1,Pab1,P04147,0.656916,NO,168,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.269,-4.733,3.464,,,,,,,0.789,,56.33,OHO,-1.10033,0.175299,0.00064061,0.656916 beta-lactamase_2500_R41F,beta-lactamase_2500_41,TEM-1,beta-lactamase_2500,P62593,0.656941,NO,41,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-0.942,-4.29,3.348,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.361275,0.00123327,0.656941 beta-lactamase_625_N274C,beta-lactamase_625_274,TEM-1,beta-lactamase_625,P62593,0.656951,NO,274,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.213352,0.0110418,0.656951 beta-lactamase_F14H,beta-lactamase_14,TEM-1,beta-lactamase,P62593,0.657028,NO,14,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-2.736,-4.866,2.13,,,,,,,1.537,,93.01,HHH,-2.26133,0.221079,0.00277095,0.657028 beta-lactamase_V117C,beta-lactamase_117,TEM-1,beta-lactamase,P62593,0.657028,NO,117,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.53,-4.787,3.257,5.33594,,H,A,1.19,-0.34,1.182,,65.03,PHB,-1.741,0.221079,0.00467906,0.657028 beta-lactamase_K213P,beta-lactamase_213,TEM-1,beta-lactamase,P62593,0.657084,NO,213,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.81,-3.901,2.091,5.63167,0.67,,A,1.59,0.29,3.924,,67.83,ABH,-1.57767,0.221079,0.00610411,0.657084 beta-lactamase_2500_R159N,beta-lactamase_2500_159,TEM-1,beta-lactamase_2500,P62593,0.657097,NO,159,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-0.94,-3.445,2.505,,0.316,,B,1.2,-0.55,2.341,,64.34,PBH,-1.011,0.361275,0.00108472,0.657097 beta-lactamase_2500_L136M,beta-lactamase_2500_136,TEM-1,beta-lactamase_2500,P62593,0.657102,NO,136,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.232,-2.988,1.756,,,H,A,0.55,-0.34,1.36,,48.95,HHH,-1.088,0.361275,0.00442304,0.657102 beta-lactamase_A245M,beta-lactamase_245,TEM-1,beta-lactamase,P62593,0.657182,NO,245,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.068,-4.569,3.501,4.78972,,E,B,0.17,-0.92,0.831,,64.69,HHH,-1.58133,0.221079,0.00391032,0.657182 beta-lactamase_G263P,beta-lactamase_263,TEM-1,beta-lactamase,P62593,0.657182,NO,263,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-2.031,-3.942,1.911,5.09799,0.517,S,l,0.77,0.31,16.425,16.425,77.62,POP,-1.78267,0.221079,0.0110582,0.657182 kka2_1:4_L241Q,kka2_1:4_241,Kka2,kka2_1:4,P00552,0.657218,NO,241,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.158,-4.313,3.155,,0.08,H,A,0.55,-0.82,1.598,,63.26,HHH,-1.58533,0.168804,0.0117299,0.657218 kka2_1:2_G189C,kka2_1:2_189,Kka2,kka2_1:2,P00552,0.657253,NO,189,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.596,-5.115,4.519,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.295029,0.00253688,0.657253 kka2_1:1_Q27H,kka2_1:1_27,Kka2,kka2_1:1,P00552,0.657429,NO,27,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-1.659,-4.651,2.992,,0.608,.,A,0.64,0.71,0.521,,65.53,PPP,-1.90733,0.520039,0.00595365,0.657429 beta-lactamase_156_T178L,beta-lactamase_156_178,TEM-1,beta-lactamase_156,P62593,0.657461,NO,178,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-0.791,-3.133,2.342,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.111618,0.000684366,0.657461 beta-lactamase_39_G76N,beta-lactamase_39_76,TEM-1,beta-lactamase_39,P62593,0.657539,NO,76,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.189,-3.655,2.466,,,H,A,0.29,-0.67,2.145,,67.83,OOH,-1.22267,0.0495842,0.00476637,0.657539 kka2_1:1_L126R,kka2_1:1_126,Kka2,kka2_1:1,P00552,0.657565,NO,126,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.246,-4.098,2.852,,0.285,S,B,0.55,0.12,0.302,,51.89,PHA,-1.744,0.520039,0.0066485,0.657565 PSD95pdz3_A376K,PSD95pdz3_376,PSD95pdz3,PSD95pdz3,P31016,0.65762,NO,376,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.307,-3.139,1.832,4.72134,,,,,17.108,,,,HHH,-1.49567,0.0758425,0.000341232,0.65762 kka2_1:1_P167I,kka2_1:1_167,Kka2,kka2_1:1,P00552,0.657856,NO,167,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-2.403,-2.742,0.339,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.520039,0.00543203,0.657856 kka2_1:8_D190A,kka2_1:8_190,Kka2,kka2_1:8,P00552,0.65794,NO,190,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.708,-3.331,2.623,,0.213,S,b,0.29,-0.82,,,,OAH,-0.711667,0.100394,0.00247989,0.65794 kka2_1:8_D190A,kka2_1:8_190,Kka2,kka2_1:8,P00552,0.65794,NO,190,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.708,-3.331,2.623,,0.213,S,b,0.29,-0.82,,,,OAH,-0.711667,0.100394,0.00247989,0.65794 beta-lactamase_A40F,beta-lactamase_40,TEM-1,beta-lactamase,P62593,0.658,NO,40,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.402,-4.227,2.825,4.9697,0.155,S,B,1.2,0.21,1.714,,73.78,OHB,-1.40267,0.221079,0.00490026,0.658 beta-lactamase_M115S,beta-lactamase_115,TEM-1,beta-lactamase,P62593,0.658,NO,115,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.389,-3.501,2.112,4.89743,0.019,E,B,1.3,0.08,1.236,,69.58,OHP,-1.25433,0.221079,0.0034337,0.658 beta-lactamase_2500_P143A,beta-lactamase_2500_143,TEM-1,beta-lactamase_2500,P62593,0.658006,NO,143,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.967,-3.126,2.159,,0.075,H,A,0.52,-0.37,0.479,,66.78,OOB,-1.354,0.361275,0.00114551,0.658006 beta-lactamase_2500_P250H,beta-lactamase_2500_250,TEM-1,beta-lactamase_2500,P62593,0.65804,NO,250,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.361275,0.00550899,0.65804 beta-lactamase_0_G265C,beta-lactamase_0_265,TEM-1,beta-lactamase_0,P62593,0.658152,NO,265,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.0500837,0.00811926,0.658152 beta-lactamase_39_L205G,beta-lactamase_39_205,TEM-1,beta-lactamase_39,P62593,0.658157,NO,205,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.922,-3.783,2.861,,,H,A,0.55,-0.46,0.846,,42.31,PHH,-1.57767,0.0495842,0.00255802,0.658157 beta-lactamase_0_L223E,beta-lactamase_0_223,TEM-1,beta-lactamase_0,P62593,0.658265,NO,223,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.055,-3.868,2.813,,0.27,,B,0.55,0.09,1.633,,74.48,HHO,-1.35033,0.0500837,0.00372793,0.658265 kka2_1:1_L39R,kka2_1:1_39,Kka2,kka2_1:1,P00552,0.658401,NO,39,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.223,-4.155,2.932,,,E,B,0.55,-1.21,0.925,,71.59,BHP,-1.69167,0.520039,0.00493618,0.658401 beta-lactamase_G154P,beta-lactamase_154,TEM-1,beta-lactamase,P62593,0.658474,NO,154,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.823,-3.881,3.058,5.40944,0.54,T,l,0.77,-0.56,2.283,,64.69,HOA,-1.635,0.221079,0.00180205,0.658474 beta-lactamase_V42N,beta-lactamase_42,TEM-1,beta-lactamase,P62593,0.658528,NO,42,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.564,-4.165,2.601,5.27904,0.017,E,B,1.64,-0.51,2.024,,63.99,BHO,-1.042,0.221079,0.00404515,0.658528 kka2_1:2_S40L,kka2_1:2_40,Kka2,kka2_1:2,P00552,0.65853,NO,40,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.645,-3.085,0.44,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.295029,0.00693477,0.65853 kka2_1:1_S251N,kka2_1:1_251,Kka2,kka2_1:1,P00552,0.658533,NO,251,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.636,-3.845,1.209,,0.712,H,A,0.27,-0.25,1.356,,71.59,APP,-2.09367,0.520039,0.0138916,0.658533 kka2_1:1_G201L,kka2_1:1_201,Kka2,kka2_1:1,P00552,0.658549,NO,201,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.56,-3.824,2.264,,0.149,T,l,0.29,-0.57,16.092,16.092,52.65,POB,-1.92233,0.520039,0.00820117,0.658549 beta-lactamase_625_L89K,beta-lactamase_625_89,TEM-1,beta-lactamase_625,P62593,0.658569,NO,89,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.096,-3.669,2.573,,0.168,T,A,0.55,0.63,1.599,,64.34,PHO,-1.75767,0.213352,0.00207068,0.658569 beta-lactamase_2500_A132S,beta-lactamase_2500_132,TEM-1,beta-lactamase_2500,P62593,0.658601,NO,132,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.9,-2.411,1.511,,,H,A,0.46,-0.93,8.408,,64.69,PHH,-1.138,0.361275,0.000962524,0.658601 beta-lactamase_0_L248F,beta-lactamase_0_248,TEM-1,beta-lactamase_0,P62593,0.658617,NO,248,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.0500837,0.00428493,0.658617 kka2_1:8_P98Y,kka2_1:8_98,Kka2,kka2_1:8,P00552,0.658638,NO,98,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.526,-4.481,2.955,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.100394,0.00622754,0.658638 kka2_1:8_P98Y,kka2_1:8_98,Kka2,kka2_1:8,P00552,0.658638,NO,98,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.526,-4.481,2.955,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.100394,0.00622754,0.658638 beta-lactamase_G114C,beta-lactamase_114,TEM-1,beta-lactamase,P62593,0.658646,NO,114,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.094,-5.014,3.92,4.92659,0.011,,p,0.77,0.35,2.148,,41.61,AOH,-1.43733,0.221079,0.00224919,0.658646 kka2_1:1_H106R,kka2_1:1_106,Kka2,kka2_1:1,P00552,0.65871,NO,106,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-3.13,-2.944,-0.186,,1.065,.,a,0.17,-0.95,2.53,,71.59,PBH,-2.10433,0.520039,0.00730778,0.65871 beta-lactamase_M1V,beta-lactamase_1,TEM-1,beta-lactamase,P62593,0.658724,NO,1,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.998,-2.535,0.537,,,,,,,,,,OHP,-1.97,0.221079,0.00162771,0.658724 beta-lactamase_P65N,beta-lactamase_65,TEM-1,beta-lactamase,P62593,0.658735,NO,65,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.894,-3.952,3.058,5.59094,0.098,E,B,0.23,-0.62,0.623,,40.56,HOH,-1.03233,0.221079,0.00152776,0.658735 Pab1_F146N,Pab1_146,Pab1,Pab1,P04147,0.658816,NO,146,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.149,-3.94,2.791,,0.006,H,A,,0.75,,,,PHP,-1.161,0.175299,0.000329265,0.658816 beta-lactamase_156_I229W,beta-lactamase_156_229,TEM-1,beta-lactamase_156,P62593,0.658824,NO,229,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.267,-5.365,4.098,,0.083,E,B,0.48,-0.76,1.114,,50,HHH,-1.58767,0.111618,0.00477249,0.658824 beta-lactamase_2500_M209C,beta-lactamase_2500_209,TEM-1,beta-lactamase_2500,P62593,0.658924,NO,209,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.442,-4.758,3.316,,,H,A,0.55,-0.97,3.229,,64.69,HHA,-1.52633,0.361275,0.00625021,0.658924 beta-lactamase_0_P217M,beta-lactamase_0_217,TEM-1,beta-lactamase_0,P62593,0.658945,NO,217,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-2.062,-4.835,2.773,,0.496,I,A,0.52,-0.33,1.087,,74.48,OOH,-1.64333,0.0500837,0.00463211,0.658945 kka2_1:1_N200K,kka2_1:1_200,Kka2,kka2_1:1,P00552,0.65896,NO,200,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-2.446,-2.694,0.248,,0.756,T,L,0.61,-0.08,17.299,17.299,64.39,APO,-2.08,0.520039,0.00838549,0.65896 beta-lactamase_39_D129S,beta-lactamase_39_129,TEM-1,beta-lactamase_39,P62593,0.65897,NO,129,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.816,-3.186,2.37,,,,B,0.75,-0.69,0.56,,34.97,PAP,-0.818,0.0495842,0.00109178,0.65897 beta-lactamase_2500_A77G,beta-lactamase_2500_77,TEM-1,beta-lactamase_2500,P62593,0.658974,NO,77,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.234,-2.31,1.076,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.361275,0.00282362,0.658974 beta-lactamase_0_E169P,beta-lactamase_0_169,TEM-1,beta-lactamase_0,P62593,0.659105,NO,169,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.23,-3.768,2.538,,0.337,,A,1.04,1,3.516,,73.08,PAH,-1.16533,0.0500837,0.00400994,0.659105 kka2_1:1_L174M,kka2_1:1_174,Kka2,kka2_1:1,P00552,0.659113,NO,174,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.952,-2.955,2.003,,,H,A,0.55,-0.31,13.276,13.276,51.89,BHB,-2.08533,0.520039,0.00438501,0.659113 kka2_1:2_R253S,kka2_1:2_253,Kka2,kka2_1:2,P00552,0.659113,NO,253,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.356,-3.389,2.033,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.295029,0.0144195,0.659113 kka2_1:2_Q27H,kka2_1:2_27,Kka2,kka2_1:2,P00552,0.659136,NO,27,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-1.659,-4.651,2.992,,0.608,.,A,0.64,0.71,0.521,,65.53,PPP,-1.90733,0.295029,0.00595365,0.659136 kka2_1:1_T146K,kka2_1:1_146,Kka2,kka2_1:1,P00552,0.659168,NO,146,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.978,-2.607,-0.371,,0.281,H,A,0.82,0.78,2.105,,92.05,BPB,-1.96833,0.520039,0.00606474,0.659168 beta-lactamase_2500_P143T,beta-lactamase_2500_143,TEM-1,beta-lactamase_2500,P62593,0.659222,NO,143,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.967,-2.616,1.649,,0.075,H,A,0.52,-0.37,0.479,,66.78,OOB,-1.354,0.361275,0.00114551,0.659222 beta-lactamase_0_R202K,beta-lactamase_0_202,TEM-1,beta-lactamase_0,P62593,0.659225,NO,202,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.292,-3.005,1.713,,0.188,H,A,1.2,0.62,7.016,,77.62,PBP,-1.54767,0.0500837,0.00321899,0.659225 kka2_1:8_F240L,kka2_1:8_240,Kka2,kka2_1:8,P00552,0.659335,NO,240,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-0.911,-2.161,1.25,,,H,A,1.62,-1.21,0.697,,50.38,BHH,-1.67267,0.100394,0.00552543,0.659335 kka2_1:8_F240L,kka2_1:8_240,Kka2,kka2_1:8,P00552,0.659335,NO,240,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-0.911,-2.161,1.25,,,H,A,1.62,-1.21,0.697,,50.38,BHH,-1.67267,0.100394,0.00552543,0.659335 kka2_1:2_V36L,kka2_1:2_36,Kka2,kka2_1:2,P00552,0.659359,NO,36,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-0.898,-2.711,1.813,,0.292,E,B,1.48,0.21,1.064,,52.27,HHH,-1.484,0.295029,0.00245633,0.659359 beta-lactamase_0_R176L,beta-lactamase_0_176,TEM-1,beta-lactamase_0,P62593,0.659386,NO,176,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-0.863,-3.358,2.495,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.0500837,0.00105554,0.659386 beta-lactamase_0_K254P,beta-lactamase_0_254,TEM-1,beta-lactamase_0,P62593,0.659481,NO,254,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.0500837,0.00369,0.659481 kka2_1:8_L193V,kka2_1:8_193,Kka2,kka2_1:8,P00552,0.659566,NO,193,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.983,-3.044,2.061,,,G,A,1.59,-1.03,2.234,,65.53,OHO,-0.965333,0.100394,0.00480179,0.659566 kka2_1:8_L193V,kka2_1:8_193,Kka2,kka2_1:8,P00552,0.659566,NO,193,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.983,-3.044,2.061,,,G,A,1.59,-1.03,2.234,,65.53,OHO,-0.965333,0.100394,0.00480179,0.659566 kka2_1:1_F37L,kka2_1:1_37,Kka2,kka2_1:1,P00552,0.659593,NO,37,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.427,-2.514,1.087,,0.219,E,B,0.58,-0.25,18.64,18.64,64.39,HHB,-1.17733,0.520039,0.00586193,0.659593 beta-lactamase_D231E,beta-lactamase_231,TEM-1,beta-lactamase,P62593,0.659692,NO,231,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.816,-2.232,1.416,5.06651,,E,B,1.22,-1.06,0.319,,65.38,HAB,-0.994,0.221079,0.00107395,0.659692 beta-lactamase_S201F,beta-lactamase_201,TEM-1,beta-lactamase,P62593,0.659809,NO,201,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.183,-4.138,2.955,4.85496,0.064,H,A,0.77,-0.07,4.045,,64.69,HPB,-1.451,0.221079,0.00198815,0.659809 kka2_1:1_A71C,kka2_1:1_71,Kka2,kka2_1:1,P00552,0.659839,NO,71,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.824,-5.109,3.285,,0.553,H,A,0.46,0.08,9.788,,64.39,HHP,-1.74033,0.520039,0.00727707,0.659839 beta-lactamase_156_P181M,beta-lactamase_156_181,TEM-1,beta-lactamase_156,P62593,0.65986,NO,181,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.813,-4.702,3.889,,,H,A,0.52,-1.14,1.078,,61.54,HOH,-1.795,0.111618,0.000703122,0.65986 beta-lactamase_0_T126L,beta-lactamase_0_126,TEM-1,beta-lactamase_0,P62593,0.659957,NO,126,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.122,-3.373,2.251,,0.05,H,A,0.22,-0.05,0.705,,44.41,HPH,-1.60467,0.0500837,0.00244552,0.659957 kka2_1:2_H106L,kka2_1:2_106,Kka2,kka2_1:2,P00552,0.660069,NO,106,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-3.13,-2.804,-0.326,,1.065,.,a,0.17,-0.95,2.53,,71.59,PBH,-2.10433,0.295029,0.00730778,0.660069 gb1_G235N,gb1_235,gb1,gb1,P06654,0.660161,NO,235,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.419,-3.259,1.84,,,,,,,0.476,,11.83,POB,-1.86433,0.177985,0.00297491,0.660161 beta-lactamase_156_W288K,beta-lactamase_156_288,TEM-1,beta-lactamase_156,P62593,0.660172,NO,288,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,,,,,,,,,,,,,BHO,,0.111618,,0.660172 beta-lactamase_I243W,beta-lactamase_243,TEM-1,beta-lactamase,P62593,0.660188,NO,243,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.532,-5.496,3.964,5.26886,,E,B,1.68,-1.24,2.289,,50,OHH,-1.46867,0.221079,0.00464034,0.660188 beta-lactamase_2500_V106R,beta-lactamase_2500_106,TEM-1,beta-lactamase_2500,P62593,0.660215,NO,106,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.218,-4.201,2.983,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.361275,0.00304168,0.660215 PSD95pdz3_A375Q,PSD95pdz3_375,PSD95pdz3,PSD95pdz3,P31016,0.660231,NO,375,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.307,-3.581,2.274,5.05512,,,,,13.888,,,,PHH,-1.43767,0.0758425,0.000356809,0.660231 beta-lactamase_625_A215Y,beta-lactamase_625_215,TEM-1,beta-lactamase_625,P62593,0.660244,NO,215,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.503,-4.339,2.836,,,,a,0.46,-0.93,3.583,,74.48,HHO,-1.42633,0.213352,0.00544007,0.660244 beta-lactamase_2500_R189D,beta-lactamase_2500_189,TEM-1,beta-lactamase_2500,P62593,0.660247,NO,189,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.844,-2.871,1.027,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.361275,0.0050699,0.660247 kka2_1:1_R143P,kka2_1:1_143,Kka2,kka2_1:1,P00552,0.660254,NO,143,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.525,-4.091,1.566,,0.325,H,A,0.16,1.22,3.6,,65.53,ABH,-1.86833,0.520039,0.00662247,0.660254 kka2_1:8_M116N,kka2_1:8_116,Kka2,kka2_1:8,P00552,0.66027,NO,116,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-2.482,-4.236,1.754,,,H,A,1.59,-0.88,4.659,,71.59,HHH,-1.63867,0.100394,0.00745147,0.66027 kka2_1:8_M116N,kka2_1:8_116,Kka2,kka2_1:8,P00552,0.66027,NO,116,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-2.482,-4.236,1.754,,,H,A,1.59,-0.88,4.659,,71.59,HHH,-1.63867,0.100394,0.00745147,0.66027 beta-lactamase_L100S,beta-lactamase_100,TEM-1,beta-lactamase,P62593,0.660461,NO,100,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.218,-3.715,2.497,5.60291,0.343,,B,1.3,0.13,1.173,,63.29,AHH,-1.23467,0.221079,0.00413885,0.660461 beta-lactamase_39_G234N,beta-lactamase_39_234,TEM-1,beta-lactamase_39,P62593,0.660655,NO,234,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.62,-3.448,2.828,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.0495842,0.000889577,0.660655 kka2_1:8_D261V,kka2_1:8_261,Kka2,kka2_1:8,P00552,0.660677,NO,261,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.708,-3.782,3.074,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.100394,0.0224846,0.660677 kka2_1:8_D261V,kka2_1:8_261,Kka2,kka2_1:8,P00552,0.660677,NO,261,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.708,-3.782,3.074,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.100394,0.0224846,0.660677 beta-lactamase_0_T107R,beta-lactamase_0_107,TEM-1,beta-lactamase_0,P62593,0.660752,NO,107,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.117,-3.76,2.643,,,G,A,0.22,-0.06,3.73,,67.83,HPA,-1.265,0.0500837,0.00239347,0.660752 kka2_1:8_L223C,kka2_1:8_223,Kka2,kka2_1:8,P00552,0.660817,NO,223,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.861,-4.71,3.849,,,H,A,1.59,-1.24,1.017,,50,HHH,-0.854333,0.100394,0.00253574,0.660817 kka2_1:8_L223C,kka2_1:8_223,Kka2,kka2_1:8,P00552,0.660817,NO,223,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.861,-4.71,3.849,,,H,A,1.59,-1.24,1.017,,50,HHH,-0.854333,0.100394,0.00253574,0.660817 beta-lactamase_2500_S266N,beta-lactamase_2500_266,TEM-1,beta-lactamase_2500,P62593,0.660831,NO,266,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.361275,0.0140785,0.660831 beta-lactamase_2500_V260T,beta-lactamase_2500_260,TEM-1,beta-lactamase_2500,P62593,0.660843,NO,260,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.361275,0.00471757,0.660843 beta-lactamase_L135S,beta-lactamase_135,TEM-1,beta-lactamase,P62593,0.660937,NO,135,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.002,-3.64,2.638,5.28497,0.117,H,A,1.07,-0.58,0.697,,43.71,PHH,-1.03767,0.221079,0.00244423,0.660937 beta-lactamase_2500_F58I,beta-lactamase_2500_58,TEM-1,beta-lactamase_2500,P62593,0.660977,NO,58,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-2.914,-3.971,1.057,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.361275,0.00523369,0.660977 beta-lactamase_0_Y95L,beta-lactamase_0_95,TEM-1,beta-lactamase_0,P62593,0.661017,NO,95,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-1.715,-2.545,0.83,,0.122,,b,0.21,-0.37,2.914,,77.62,BHP,-2.16167,0.0500837,0.00479449,0.661017 kka2_1:8_L70F,kka2_1:8_70,Kka2,kka2_1:8,P00552,0.661046,NO,70,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.017,-3.762,2.745,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.100394,0.00411884,0.661046 kka2_1:8_L70F,kka2_1:8_70,Kka2,kka2_1:8,P00552,0.661046,NO,70,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.017,-3.762,2.745,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.100394,0.00411884,0.661046 beta-lactamase_T27D,beta-lactamase_27,TEM-1,beta-lactamase,P62593,0.661062,NO,27,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.905,-3.5,1.595,5.39752,0.007,H,A,0.69,-0.37,0.745,,93.01,APH,-1.97933,0.221079,0.00306559,0.661062 beta-lactamase_D231G,beta-lactamase_231,TEM-1,beta-lactamase,P62593,0.66107,NO,231,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.816,-3.182,2.366,5.06651,,E,B,1.22,-1.06,0.319,,65.38,HAB,-0.994,0.221079,0.00107395,0.66107 kka2_1:2_A229C,kka2_1:2_229,Kka2,kka2_1:2,P00552,0.661086,NO,229,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.739,-5.054,3.315,,0.32,H,A,0.46,-0.7,6.549,,63.64,HHA,-1.851,0.295029,0.00942138,0.661086 kka2_1:1_G210V,kka2_1:1_210,Kka2,kka2_1:1,P00552,0.661163,NO,210,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.095,-3.659,2.564,,0.103,T,A,0.29,-0.62,14.483,14.483,50,OOB,-0.966667,0.520039,0.00598378,0.661163 beta-lactamase_G142A,beta-lactamase_142,TEM-1,beta-lactamase,P62593,0.66119,NO,142,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.707,-2.85,2.143,4.55474,0.034,,p,0.77,-0.64,1.947,,64.69,OOO,-0.834,0.221079,0.00060149,0.66119 kka2_1:2_D62H,kka2_1:2_62,Kka2,kka2_1:2,P00552,0.661205,NO,62,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.591,-3.352,1.761,,0.262,H,A,0.75,0.08,10.048,10.048,64.39,PAA,-1.77833,0.295029,0.00744243,0.661205 beta-lactamase_V29P,beta-lactamase_29,TEM-1,beta-lactamase,P62593,0.661226,NO,29,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-2.856,-3.853,0.997,5.58481,0.733,H,A,0.23,-0.78,1.287,,93.01,HHB,-2.24733,0.221079,0.00318969,0.661226 kka2_1:1_Q27P,kka2_1:1_27,Kka2,kka2_1:1,P00552,0.661242,NO,27,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-1.659,-3,1.341,,0.608,.,A,0.64,0.71,0.521,,65.53,PPP,-1.90733,0.520039,0.00595365,0.661242 kka2_1:4_D154S,kka2_1:4_154,Kka2,kka2_1:4,P00552,0.661283,NO,154,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.876,-3.211,2.335,,0.457,,b,0.29,1.48,15.641,15.641,52.65,HAP,-1.52467,0.168804,0.00292633,0.661283 beta-lactamase_S264E,beta-lactamase_264,TEM-1,beta-lactamase,P62593,0.66129,NO,264,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.985,-3.618,1.633,4.67475,0.04,,B,0.25,0.29,34.251,34.251,73.78,OPP,-2.19867,0.221079,0.0119399,0.66129 Ubiquitin_A46Y,Ubiquitin_46,Uba1,Ubiquitin,P0CG48,0.66129,NO,46,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.77,-3.125,1.355,5.38761,0.398,T,L,2.34,-0.8,6.506,,51.09,HHO,-1.505,0.205827,0.000581142,0.66129 Ubiquitin_I61G,Ubiquitin_61,Uba1,Ubiquitin,P0CG48,0.66129,NO,61,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.514,-2.744,1.23,5.19922,0.038,,B,1,-0.76,1.953,,24.53,PHP,-1.70833,0.205827,0.000738268,0.66129 Ubiquitin_R72T,Ubiquitin_72,Uba1,Ubiquitin,P0CG48,0.66129,NO,72,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.034,-2.895,0.861,5.19484,0.077,,B,1.41,-0.1,9.638,9.638,42.77,HBH,-1.82733,0.205827,0.000768249,0.66129 Ubiquitin_T12A,Ubiquitin_12,Uba1,Ubiquitin,P0CG48,0.66129,NO,12,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.288,-2.919,1.631,4.93973,0.417,E,B,0.8,0.12,2.762,,25.84,BPH,-1.39867,0.205827,0.000657544,0.66129 beta-lactamase_0_I171A,beta-lactamase_0_171,TEM-1,beta-lactamase_0,P62593,0.661297,NO,171,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-2.431,-2.242,-0.189,,0.361,,B,0.48,0.53,16.954,16.954,77.62,HHO,-1.55533,0.0500837,0.00623355,0.661297 beta-lactamase_2500_M270G,beta-lactamase_2500_270,TEM-1,beta-lactamase_2500,P62593,0.661313,NO,270,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.723,,,,0.422,H,A,1.59,1.15,2.029,,64.34,PHA,-1.70933,0.361275,0.00767762,0.661313 beta-lactamase_L89K,beta-lactamase_89,TEM-1,beta-lactamase,P62593,0.661337,NO,89,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.096,-3.669,2.573,5.41092,0.168,T,A,1.75,0.63,1.599,,64.34,PHO,-1.75767,0.221079,0.00207068,0.661337 beta-lactamase_39_M67W,beta-lactamase_39_67,TEM-1,beta-lactamase_39,P62593,0.661386,NO,67,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-2.231,-5.379,3.148,,0.006,G,P,0.55,-0.81,1.463,,65.03,HHP,-1.502,0.0495842,0.00409753,0.661386 kka2_1:4_V186A,kka2_1:4_186,Kka2,kka2_1:4,P00552,0.661421,NO,186,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.011,-3.042,2.031,,,E,B,0.44,-0.61,0.679,,45.83,HHP,-1.10967,0.168804,0.00409703,0.661421 gb1_A252M,gb1_252,gb1,gb1,P06654,0.661486,NO,252,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.175,-4.215,3.04,,,,,,,,,,PHA,-1.55967,0.177985,0.00125598,0.661486 gb1_G240F,gb1_240,gb1,gb1,P06654,0.661486,NO,240,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.921,-4.028,3.107,,,,,,,,,,BOA,-1.87867,0.177985,0.00270792,0.661486 gb1_L233Y,gb1_233,gb1,gb1,P06654,0.661486,NO,233,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-2.678,-3.803,1.125,,,,,,,0.822,,45.54,HHP,-2.30267,0.177985,0.00266958,0.661486 kka2_1:1_R258S,kka2_1:1_258,Kka2,kka2_1:1,P00552,0.661668,NO,258,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.626,-3.501,1.875,,0.316,H,A,1.2,-0.85,7.485,7.485,53.03,HBH,-1.25933,0.520039,0.00983174,0.661668 beta-lactamase_2500_G52D,beta-lactamase_2500_52,TEM-1,beta-lactamase_2500,P62593,0.661882,NO,52,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.149,-2.123,0.974,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.361275,0.00340138,0.661882 kka2_1:1_G164V,kka2_1:1_164,Kka2,kka2_1:1,P00552,0.6619,NO,164,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.869,-3.836,2.967,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.520039,0.00442091,0.6619 kka2_1:8_A34M,kka2_1:8_34,Kka2,kka2_1:8,P00552,0.661921,NO,34,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.928,-4.54,3.612,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.100394,0.00343484,0.661921 kka2_1:8_A34M,kka2_1:8_34,Kka2,kka2_1:8,P00552,0.661921,NO,34,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.928,-4.54,3.612,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.100394,0.00343484,0.661921 beta-lactamase_0_K254N,beta-lactamase_0_254,TEM-1,beta-lactamase_0,P62593,0.661926,NO,254,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.0500837,0.00369,0.661926 kka2_1:1_I228R,kka2_1:1_228,Kka2,kka2_1:1,P00552,0.66193,NO,228,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.142,-4.209,3.067,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.520039,0.00458834,0.66193 beta-lactamase_2500_F228R,beta-lactamase_2500_228,TEM-1,beta-lactamase_2500,P62593,0.662016,NO,228,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-2.342,-2.044,-0.298,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.361275,0.0046669,0.662016 kka2_1:4_R226S,kka2_1:4_226,Kka2,kka2_1:4,P00552,0.662086,NO,226,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.392,-2.638,1.246,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.168804,0.0108032,0.662086 beta-lactamase_P105W,beta-lactamase_105,TEM-1,beta-lactamase,P62593,0.662136,NO,105,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.813,-5.545,4.732,5.08236,0.226,T,A,0.98,0.8,1.154,,63.29,POH,-1.01533,0.221079,0.0011981,0.662136 beta-lactamase_625_Q276D,beta-lactamase_625_276,TEM-1,beta-lactamase_625,P62593,0.662191,NO,276,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.213352,0.0191712,0.662191 kka2_1:1_Q163I,kka2_1:1_163,Kka2,kka2_1:1,P00552,0.662311,NO,163,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.162,-3.594,1.432,,0.58,T,B,0.64,1.85,2.779,,64.02,BPO,-1.78333,0.520039,0.00719507,0.662311 beta-lactamase_0_L89R,beta-lactamase_0_89,TEM-1,beta-lactamase_0,P62593,0.662336,NO,89,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.096,-3.963,2.867,,0.168,T,A,0.55,0.63,2.373,,64.34,PHO,-1.75767,0.0500837,0.00207068,0.662336 kka2_1:2_E161W,kka2_1:2_161,Kka2,kka2_1:2,P00552,0.662363,NO,161,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.581,-5.534,3.953,,0.829,G,A,1.52,2.24,1.612,,92.05,AAB,-1.861,0.295029,0.00760103,0.662363 kka2_1:2_L102V,kka2_1:2_102,Kka2,kka2_1:2,P00552,0.662363,NO,102,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.804,-2.905,2.101,,,T,A,1.59,-1.17,4.258,,42.42,AHH,-1.398,0.295029,0.00201332,0.662363 kka2_1:2_G88R,kka2_1:2_88,Kka2,kka2_1:2,P00552,0.662403,NO,88,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.689,-3.209,1.52,,0.54,S,l,0.75,1.51,2.814,,65.53,HOB,-1.718,0.295029,0.00685559,0.662403 kka2_1:4_L243Y,kka2_1:4_243,Kka2,kka2_1:4,P00552,0.662463,NO,243,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-2.651,-4.342,1.691,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.168804,0.00884927,0.662463 Pab1_H172K,Pab1_172,Pab1,Pab1,P04147,0.662492,NO,172,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-1.21,-3.274,2.064,,0.076,E,B,0.35,-0.87,,,,HBH,-1.26667,0.175299,0.000296642,0.662492 kka2_1:2_L223R,kka2_1:2_223,Kka2,kka2_1:2,P00552,0.662565,NO,223,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.861,-4.044,3.183,,,H,A,0.55,-1.24,0.266,,50,HHH,-0.854333,0.295029,0.00253574,0.662565 beta-lactamase_0_A170Y,beta-lactamase_0_170,TEM-1,beta-lactamase_0,P62593,0.662625,NO,170,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.237,-4.057,2.82,,0.126,,L,0.46,-0.35,2.427,,64.69,AHH,-1.63267,0.0500837,0.00431903,0.662625 beta-lactamase_625_L197C,beta-lactamase_625_197,TEM-1,beta-lactamase_625,P62593,0.662669,NO,197,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.853,-4.635,3.782,,0.007,S,B,0.55,0.33,1.756,,60.14,HHP,-1.833,0.213352,0.00144602,0.662669 beta-lactamase_156_A215D,beta-lactamase_156_215,TEM-1,beta-lactamase_156,P62593,0.662704,NO,215,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.503,-3.621,2.118,,,,a,0.46,-0.93,3.583,,74.48,HHO,-1.42633,0.111618,0.00544007,0.662704 gb1_G235K,gb1_235,gb1,gb1,P06654,0.662799,NO,235,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.419,-3.374,1.955,,,,,,,0.476,,11.83,POB,-1.86433,0.177985,0.00297491,0.662799 kka2_1:1_A34E,kka2_1:1_34,Kka2,kka2_1:1,P00552,0.662828,NO,34,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.928,-3.441,2.513,,0.417,.,B,0.46,2.29,0.262,,52.27,AHH,-1.747,0.520039,0.00343484,0.662828 kka2_1:2_I228V,kka2_1:2_228,Kka2,kka2_1:2,P00552,0.662896,NO,228,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.142,-1.946,0.804,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.295029,0.00458834,0.662896 beta-lactamase_2500_V106F,beta-lactamase_2500_106,TEM-1,beta-lactamase_2500,P62593,0.663064,NO,106,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.218,-2.585,1.367,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.361275,0.00304168,0.663064 beta-lactamase_0_D252K,beta-lactamase_0_252,TEM-1,beta-lactamase_0,P62593,0.663065,NO,252,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.94,-3.575,1.635,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.0500837,0.00575769,0.663065 beta-lactamase_P143N,beta-lactamase_143,TEM-1,beta-lactamase,P62593,0.663067,NO,143,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.967,-3.954,2.987,5.16366,0.075,H,A,0.99,-0.37,0.479,,66.78,OOB,-1.354,0.221079,0.00114551,0.663067 kka2_1:1_T73Q,kka2_1:1_73,Kka2,kka2_1:1,P00552,0.663075,NO,73,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.51,-1.983,-0.527,,0.309,H,A,0.22,0.35,4.126,,56.06,PPO,-2.02333,0.520039,0.00628605,0.663075 beta-lactamase_625_P143F,beta-lactamase_625_143,TEM-1,beta-lactamase_625,P62593,0.663076,NO,143,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.967,-4.308,3.341,,0.075,H,A,0.52,-0.37,1.445,,66.78,OOB,-1.354,0.213352,0.00114551,0.663076 kka2_1:2_P109A,kka2_1:2_109,Kka2,kka2_1:2,P00552,0.663084,NO,109,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.412,-1.957,0.545,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.295029,0.0070929,0.663084 beta-lactamase_0_L146C,beta-lactamase_0_146,TEM-1,beta-lactamase_0,P62593,0.663101,NO,146,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.462,-4.847,3.385,,0.007,H,A,0.55,-0.56,2.051,,64.69,AHP,-1.656,0.0500837,0.00474542,0.663101 kka2_1:8_G233S,kka2_1:8_233,Kka2,kka2_1:8,P00552,0.663115,NO,233,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.748,-3.234,2.486,,0.172,,b,0.75,-0.27,1.134,,49.24,HOO,-1.72067,0.100394,0.00232366,0.663115 kka2_1:8_G233S,kka2_1:8_233,Kka2,kka2_1:8,P00552,0.663115,NO,233,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.748,-3.234,2.486,,0.172,,b,0.75,-0.27,1.134,,49.24,HOO,-1.72067,0.100394,0.00232366,0.663115 kka2_1:1_L102P,kka2_1:1_102,Kka2,kka2_1:1,P00552,0.663152,NO,102,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.804,-4.131,3.327,,,T,A,0.55,-1.17,4.258,,42.42,AHH,-1.398,0.520039,0.00201332,0.663152 kka2_1:1_A34V,kka2_1:1_34,Kka2,kka2_1:1,P00552,0.663215,NO,34,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.928,-3.231,2.303,,0.417,.,B,0.46,2.29,0.262,,52.27,AHH,-1.747,0.520039,0.00343484,0.663215 beta-lactamase_2500_S122P,beta-lactamase_2500_122,TEM-1,beta-lactamase_2500,P62593,0.663334,NO,122,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.406,-4.011,1.605,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.361275,0.00497825,0.663334 Pab1_A158F,Pab1_158,Pab1,Pab1,P04147,0.663351,NO,158,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.154,-3.878,2.724,,,,,,,1.197,,56.33,HHP,-1.40733,0.175299,0.000649733,0.663351 beta-lactamase_625_L160P,beta-lactamase_625_160,TEM-1,beta-lactamase_625,P62593,0.663366,NO,160,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.977,-4.121,3.144,,0.022,,B,0.55,-0.6,0.237,,44.41,BHA,-0.936,0.213352,0.00193775,0.663366 beta-lactamase_L197A,beta-lactamase_197,TEM-1,beta-lactamase,P62593,0.663376,NO,197,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.853,-2.357,1.504,5.19172,0.007,S,B,1.3,0.33,1.756,,60.14,HHP,-1.833,0.221079,0.00144602,0.663376 beta-lactamase_0_L111E,beta-lactamase_0_111,TEM-1,beta-lactamase_0,P62593,0.663503,NO,111,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.76,-3.773,2.013,,0.328,T,A,0.55,0.93,1.966,,64.34,BHP,-1.884,0.0500837,0.00480671,0.663503 kka2_1:1_D180Q,kka2_1:1_180,Kka2,kka2_1:1,P00552,0.663535,NO,180,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.416,-3.007,0.591,,1.03,S,a,0.75,1.5,1.534,,71.59,OAO,-2.02933,0.520039,0.00756412,0.663535 beta-lactamase_W286L,beta-lactamase_286,TEM-1,beta-lactamase,P62593,0.663555,NO,286,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-1.111,-3.175,2.064,6.64456,0.492,,?,0.01,0.6,,,,BHX,-1.478,0.221079,,0.663555 kka2_1:1_Y218C,kka2_1:1_218,Kka2,kka2_1:1,P00552,0.66364,NO,218,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-1.438,-2.974,1.536,,0.122,H,A,1.25,-0.69,3.059,,56.06,BHP,-1.17533,0.520039,0.0126098,0.66364 kka2_1:4_P194S,kka2_1:4_194,Kka2,kka2_1:4,P00552,0.663655,NO,194,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.846,-2.623,1.777,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.168804,0.00314194,0.663655 kka2_1:4_D157V,kka2_1:4_157,Kka2,kka2_1:4,P00552,0.663679,NO,157,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.993,-3.837,2.844,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.168804,0.0042313,0.663679 beta-lactamase_0_V42H,beta-lactamase_0_42,TEM-1,beta-lactamase_0,P62593,0.663688,NO,42,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.564,-4.991,3.427,,0.017,E,B,0.44,-0.51,1.659,,63.99,BHO,-1.042,0.0500837,0.00404515,0.663688 kka2_1:8_H135A,kka2_1:8_135,Kka2,kka2_1:8,P00552,0.663747,NO,135,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-1.331,-2.452,1.121,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.100394,0.00532566,0.663747 kka2_1:8_H135A,kka2_1:8_135,Kka2,kka2_1:8,P00552,0.663747,NO,135,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-1.331,-2.452,1.121,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.100394,0.00532566,0.663747 beta-lactamase_S264F,beta-lactamase_264,TEM-1,beta-lactamase,P62593,0.663882,NO,264,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.985,-3.179,1.194,4.67475,0.04,,B,0.25,0.29,34.251,34.251,73.78,OPP,-2.19867,0.221079,0.0119399,0.663882 beta-lactamase_T116F,beta-lactamase_116,TEM-1,beta-lactamase,P62593,0.663882,NO,116,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.28,-4.243,2.963,4.78335,0.115,E,B,0.69,-0.12,0.343,,67.48,HPH,-1.39967,0.221079,0.00336175,0.663882 kka2_1:1_P12A,kka2_1:1_12,Kka2,kka2_1:1,P00552,0.663904,NO,12,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.853,-2.153,1.3,,,.,B,0.52,1.25,0.261,,48.11,POH,-1.80767,0.520039,0.00500011,0.663904 kka2_1:1_H106K,kka2_1:1_106,Kka2,kka2_1:1,P00552,0.663946,NO,106,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-3.13,-3.67,0.54,,1.065,.,a,0.17,-0.95,2.53,,71.59,PBH,-2.10433,0.520039,0.00730778,0.663946 beta-lactamase_F228E,beta-lactamase_228,TEM-1,beta-lactamase,P62593,0.664019,NO,228,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-2.342,-3.551,1.209,5.33448,0.154,E,B,1.1,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.221079,0.0046669,0.664019 beta-lactamase_S264D,beta-lactamase_264,TEM-1,beta-lactamase,P62593,0.66418,NO,264,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.985,-3.669,1.684,4.67475,0.04,,B,0.25,0.29,34.251,34.251,73.78,OPP,-2.19867,0.221079,0.0119399,0.66418 kka2_1:1_V49G,kka2_1:1_49,Kka2,kka2_1:1,P00552,0.664186,NO,49,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.614,-3.739,2.125,,,E,B,0.44,-0.77,3.665,3.665,64.39,HHB,-1.3,0.520039,0.00615685,0.664186 kka2_1:1_F48S,kka2_1:1_48,Kka2,kka2_1:1,P00552,0.664289,NO,48,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.453,-3.787,2.334,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.520039,0.00475422,0.664289 kka2_1:1_E231A,kka2_1:1_231,Kka2,kka2_1:1,P00552,0.664339,NO,231,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.002,-3.339,1.337,,0.503,H,A,1.04,-0.23,25.629,25.629,63.26,AAH,-2.06267,0.520039,0.00732383,0.664339 beta-lactamase_2500_T139K,beta-lactamase_2500_139,TEM-1,beta-lactamase_2500,P62593,0.664351,NO,139,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.901,-3.403,1.502,,0.216,H,A,0.22,0.39,2.256,,77.62,PPH,-2.04667,0.361275,0.00441837,0.664351 kka2_1:8_G205V,kka2_1:8_205,Kka2,kka2_1:8,P00552,0.664396,NO,205,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.596,-3.782,3.186,,,E,b,0.75,-1.05,,,,POH,-1.09933,0.100394,0.00221855,0.664396 kka2_1:8_G205V,kka2_1:8_205,Kka2,kka2_1:8,P00552,0.664396,NO,205,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.596,-3.782,3.186,,,E,b,0.75,-1.05,,,,POH,-1.09933,0.100394,0.00221855,0.664396 beta-lactamase_2500_T263D,beta-lactamase_2500_263,TEM-1,beta-lactamase_2500,P62593,0.664408,NO,263,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.361275,0.0110582,0.664408 beta-lactamase_2500_V78T,beta-lactamase_2500_78,TEM-1,beta-lactamase_2500,P62593,0.664551,NO,78,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.459,-3.492,2.033,,,H,A,0.44,-0.47,31.376,31.376,63.64,HHH,-1.17833,0.361275,0.00492501,0.664551 kka2_1:8_N195K,kka2_1:8_195,Kka2,kka2_1:8,P00552,0.664579,NO,195,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-0.836,-3.304,2.468,,0.037,G,A,0.43,-1.36,1.108,,48.11,OPH,-1.26567,0.100394,0.00276134,0.664579 kka2_1:8_N195K,kka2_1:8_195,Kka2,kka2_1:8,P00552,0.664579,NO,195,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-0.836,-3.304,2.468,,0.037,G,A,0.43,-1.36,1.108,,48.11,OPH,-1.26567,0.100394,0.00276134,0.664579 beta-lactamase_0_D161H,beta-lactamase_0_161,TEM-1,beta-lactamase_0,P62593,0.664671,NO,161,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.891,-4.479,3.588,,0.341,,A,0.75,-0.52,0.795,,61.19,HAB,-0.961333,0.0500837,0.000897697,0.664671 beta-lactamase_0_Y262I,beta-lactamase_0_262,TEM-1,beta-lactamase_0,P62593,0.664753,NO,262,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.0500837,0.00853516,0.664753 beta-lactamase_39_G240L,beta-lactamase_39_240,TEM-1,beta-lactamase_39,P62593,0.664779,NO,240,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.0495842,0.00591201,0.664779 kka2_1:1_M116T,kka2_1:1_116,Kka2,kka2_1:1,P00552,0.664808,NO,116,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-2.482,-2.959,0.477,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.520039,0.00745147,0.664808 beta-lactamase_39_T158Y,beta-lactamase_39_158,TEM-1,beta-lactamase_39,P62593,0.664842,NO,158,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.116,-4.258,3.142,,0.036,,B,0.22,-0.85,2.755,,69.58,HPB,-1.269,0.0495842,0.00341825,0.664842 beta-lactamase_156_D174W,beta-lactamase_156_174,TEM-1,beta-lactamase_156,P62593,0.664846,NO,174,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.738,-5.547,4.809,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.111618,0.00125633,0.664846 kka2_1:1_D23C,kka2_1:1_23,Kka2,kka2_1:1,P00552,0.664847,NO,23,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.459,-3.701,1.242,,0.695,E,B,0.75,-0.65,2.655,,65.53,HAH,-1.94033,0.520039,0.007195,0.664847 kka2_1:8_F264C,kka2_1:8_264,Kka2,kka2_1:8,P00552,0.664944,NO,264,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.02,-4.944,3.924,,0.296,,?,1.62,0.02,1.553,,71.59,HHO,-0.9655,0.100394,,0.664944 kka2_1:8_F264C,kka2_1:8_264,Kka2,kka2_1:8,P00552,0.664944,NO,264,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.02,-4.944,3.924,,0.296,,?,1.62,0.02,1.553,,71.59,HHO,-0.9655,0.100394,,0.664944 beta-lactamase_G239A,beta-lactamase_239,TEM-1,beta-lactamase,P62593,0.665068,NO,239,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.819,-2.289,1.47,4.85529,0.115,T,l,0.77,-0.62,1.817,,42.31,BOP,-1.45267,0.221079,0.00213852,0.665068 kka2_1:4_D216Y,kka2_1:4_216,Kka2,kka2_1:4,P00552,0.665188,NO,216,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.785,-4.248,3.463,,0.018,E,B,0.75,-0.51,0.112,,19.32,HAB,-0.970333,0.168804,0.00229969,0.665188 beta-lactamase_A23T,beta-lactamase_23,TEM-1,beta-lactamase,P62593,0.665239,NO,23,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.548,-2.56,1.012,,,,,,,0.801,,93.01,HHB,-2.235,0.221079,0.00245563,0.665239 beta-lactamase_0_I171H,beta-lactamase_0_171,TEM-1,beta-lactamase_0,P62593,0.665253,NO,171,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-2.431,-4.817,2.386,,0.361,,B,0.48,0.53,16.954,16.954,77.62,HHO,-1.55533,0.0500837,0.00623355,0.665253 beta-lactamase_625_I261T,beta-lactamase_625_261,TEM-1,beta-lactamase_625,P62593,0.665371,NO,261,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-2.88,-1.929,-0.951,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.213352,0.0123091,0.665371 Pab1_D136P,Pab1_136,Pab1,Pab1,P04147,0.66539,NO,136,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.602,-3.634,2.032,,,,,,,,,,OAH,-1.42367,0.175299,0.00227029,0.66539 beta-lactamase_625_G154L,beta-lactamase_625_154,TEM-1,beta-lactamase_625,P62593,0.6654,NO,154,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.823,-3.779,2.956,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.213352,0.00180205,0.6654 PSD95pdz3_L379Y,PSD95pdz3_379,PSD95pdz3,PSD95pdz3,P31016,0.665435,NO,379,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.347,-3.619,2.272,5.37777,,,,,16.8762,,,,HHB,-1.35667,0.0758425,0.00029733,0.665435 beta-lactamase_156_V157P,beta-lactamase_156_157,TEM-1,beta-lactamase_156,P62593,0.665494,NO,157,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.751,-4.03,2.279,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.111618,0.00506849,0.665494 kka2_1:2_Q219A,kka2_1:2_219,Kka2,kka2_1:2,P00552,0.665558,NO,219,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-0.93,-3.129,2.199,,0.088,H,A,0.4,-0.85,1.917,,50,HPA,-1.05167,0.295029,0.00237913,0.665558 kka2_1:4_A137E,kka2_1:4_137,Kka2,kka2_1:4,P00552,0.665625,NO,137,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.156,-3.863,1.707,,0.029,H,A,0.46,0.34,2.227,,63.26,PHB,-2.559,0.168804,0.00515054,0.665625 kka2_1:2_D183E,kka2_1:2_183,Kka2,kka2_1:2,P00552,0.665662,NO,183,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.204,-2.074,0.87,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.295029,0.00426304,0.665662 kka2_1:1_R143V,kka2_1:1_143,Kka2,kka2_1:1,P00552,0.665746,NO,143,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.525,-2.516,-0.009,,0.325,H,A,0.16,1.22,3.6,,65.53,ABH,-1.86833,0.520039,0.00662247,0.665746 kka2_1:1_G151C,kka2_1:1_151,Kka2,kka2_1:1,P00552,0.665818,NO,151,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.873,-5.156,4.283,,0.678,T,l,0.29,1.36,0.226,,49.62,HOH,-1.11433,0.520039,0.00339918,0.665818 kka2_1:1_A87G,kka2_1:1_87,Kka2,kka2_1:1,P00552,0.665835,NO,87,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.917,-2.002,0.085,,1.039,S,L,0.46,1.57,20.738,20.738,65.53,AHO,-1.822,0.520039,0.00791281,0.665835 kka2_1:1_E111G,kka2_1:1_111,Kka2,kka2_1:1,P00552,0.665888,NO,111,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.28,-2.822,0.542,,0.155,H,A,1.52,-1.14,15.716,15.716,65.53,HAB,-2.27833,0.520039,0.00746789,0.665888 kka2_1:4_A222V,kka2_1:4_222,Kka2,kka2_1:4,P00552,0.665917,NO,222,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.725,-3.107,2.382,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.168804,0.00207657,0.665917 beta-lactamase_2500_E56V,beta-lactamase_2500_56,TEM-1,beta-lactamase_2500,P62593,0.665952,NO,56,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.043,-3.397,1.354,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.361275,0.00238534,0.665952 kka2_1:4_L39W,kka2_1:4_39,Kka2,kka2_1:4,P00552,0.665971,NO,39,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.223,-5.273,4.05,,,E,B,0.55,-1.21,1.998,,71.59,BHP,-1.69167,0.168804,0.00493618,0.665971 beta-lactamase_0_S256P,beta-lactamase_0_256,TEM-1,beta-lactamase_0,P62593,0.666066,NO,256,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.0500837,0.00710634,0.666066 kka2_1:2_L93R,kka2_1:2_93,Kka2,kka2_1:2,P00552,0.666276,NO,93,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.815,-2.776,1.961,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.295029,0.00131498,0.666276 beta-lactamase_0_W227V,beta-lactamase_0_227,TEM-1,beta-lactamase_0,P62593,0.66641,NO,227,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-0.982,-3.747,2.765,,0.272,,B,0.47,-0.29,3.782,,74.48,OHH,-1.595,0.0500837,0.00226019,0.66641 kka2_1:8_L170Y,kka2_1:8_170,Kka2,kka2_1:8,P00552,0.666604,NO,170,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.28,-4.115,2.835,,0.029,H,A,1.59,0.11,1.453,,62.5,AHH,-1.534,0.100394,0.00730791,0.666604 kka2_1:8_L170Y,kka2_1:8_170,Kka2,kka2_1:8,P00552,0.666604,NO,170,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.28,-4.115,2.835,,0.029,H,A,1.59,0.11,1.453,,62.5,AHH,-1.534,0.100394,0.00730791,0.666604 beta-lactamase_0_S233K,beta-lactamase_0_233,TEM-1,beta-lactamase_0,P62593,0.666644,NO,233,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.886,-3.496,1.61,,0.016,E,B,0.27,-1.01,3.579,,77.62,BPO,-1.17267,0.0500837,0.00311415,0.666644 beta-lactamase_2500_R202N,beta-lactamase_2500_202,TEM-1,beta-lactamase_2500,P62593,0.66684,NO,202,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.292,-3.543,2.251,,0.188,H,A,1.2,0.62,3.734,,77.62,PBP,-1.54767,0.361275,0.00321899,0.66684 beta-lactamase_0_P25Y,beta-lactamase_0_25,TEM-1,beta-lactamase_0,P62593,0.666874,NO,25,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.526,-4.327,2.801,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.0500837,0.00347571,0.666874 beta-lactamase_39_W227L,beta-lactamase_39_227,TEM-1,beta-lactamase_39,P62593,0.666915,NO,227,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-0.982,-3.387,2.405,,0.272,,B,0.47,-0.29,1.37,,74.48,OHH,-1.595,0.0495842,0.00226019,0.666915 beta-lactamase_2500_Y103P,beta-lactamase_2500_103,TEM-1,beta-lactamase_2500,P62593,0.66692,NO,103,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-1.33,-4.138,2.808,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.361275,0.00443048,0.66692 kka2_1:2_E59D,kka2_1:2_59,Kka2,kka2_1:2,P00552,0.666921,NO,59,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-0.952,-2.395,1.443,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.295029,0.00280355,0.666921 beta-lactamase_156_L135G,beta-lactamase_156_135,TEM-1,beta-lactamase_156,P62593,0.667055,NO,135,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.002,-3.837,2.835,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.111618,0.00244423,0.667055 beta-lactamase_2500_L111P,beta-lactamase_2500_111,TEM-1,beta-lactamase_2500,P62593,0.667101,NO,111,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.76,-4.076,2.316,,0.328,T,A,0.55,0.93,1.966,,64.34,BHP,-1.884,0.361275,0.00480671,0.667101 beta-lactamase_0_D231N,beta-lactamase_0_231,TEM-1,beta-lactamase_0,P62593,0.667126,NO,231,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.816,-3.272,2.456,,,E,B,0.75,-1.06,4.975,,65.38,HAB,-0.994,0.0500837,0.00107395,0.667126 beta-lactamase_L219P,beta-lactamase_219,TEM-1,beta-lactamase,P62593,0.667191,NO,219,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.313,-4.214,2.901,5.74153,,I,A,0.84,-0.51,2.321,,74.48,HHB,-1.21533,0.221079,0.00664345,0.667191 kka2_1:1_A13D,kka2_1:1_13,Kka2,kka2_1:1,P00552,0.667247,NO,13,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.248,-2.729,0.481,,0.689,G,A,0.46,0.99,25.015,25.015,92.05,OHH,-1.646,0.520039,0.00784241,0.667247 kka2_1:4_P194C,kka2_1:4_194,Kka2,kka2_1:4,P00552,0.667261,NO,194,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.846,-5.109,4.263,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.168804,0.00314194,0.667261 beta-lactamase_2500_A200W,beta-lactamase_2500_200,TEM-1,beta-lactamase_2500,P62593,0.66727,NO,200,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.878,-5.525,3.647,,0.757,H,A,0.46,-0.19,0.436,,77.62,HHP,-2.001,0.361275,0.0060056,0.66727 beta-lactamase_D177N,beta-lactamase_177,TEM-1,beta-lactamase,P62593,0.667411,NO,177,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.967,-2.571,1.604,5.08038,0.006,T,L,1.59,-1.02,3.536,,64.69,BAP,-0.873667,0.221079,0.000864022,0.667411 beta-lactamase_A40I,beta-lactamase_40,TEM-1,beta-lactamase,P62593,0.667475,NO,40,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.402,-3.742,2.34,4.9697,0.155,S,B,1.2,0.21,1.714,,73.78,OHB,-1.40267,0.221079,0.00490026,0.667475 kka2_1:4_P167G,kka2_1:4_167,Kka2,kka2_1:4,P00552,0.667736,NO,167,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-2.403,-3.388,0.985,,0.18,H,A,0.52,0.75,3.6,,64.39,HOH,-2.26633,0.168804,0.00543203,0.667736 kka2_1:8_L123P,kka2_1:8_123,Kka2,kka2_1:8,P00552,0.667848,NO,123,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.888,-4.155,3.267,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.100394,0.00325188,0.667848 kka2_1:8_L123P,kka2_1:8_123,Kka2,kka2_1:8,P00552,0.667848,NO,123,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.888,-4.155,3.267,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.100394,0.00325188,0.667848 beta-lactamase_2500_I54H,beta-lactamase_2500_54,TEM-1,beta-lactamase_2500,P62593,0.667849,NO,54,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-2.838,-3.42,0.582,,0.669,E,B,0.48,-0.14,3.946,,73.78,BHH,-2.337,0.361275,0.00403589,0.667849 beta-lactamase_2500_P181V,beta-lactamase_2500_181,TEM-1,beta-lactamase_2500,P62593,0.667854,NO,181,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.813,-3.492,2.679,,,H,A,0.52,-1.14,1.946,,61.54,HOH,-1.795,0.361275,0.000703122,0.667854 kka2_1:4_H162V,kka2_1:4_162,Kka2,kka2_1:4,P00552,0.667866,NO,162,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-2.319,-3.881,1.562,,0.071,G,A,0.17,1.01,3.187,,64.39,ABP,-2.02067,0.168804,0.00616145,0.667866 kka2_1:4_G233C,kka2_1:4_233,Kka2,kka2_1:4,P00552,0.667905,NO,233,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.748,-5.16,4.412,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.168804,0.00232366,0.667905 Pab1_H172S,Pab1_172,Pab1,Pab1,P04147,0.667971,NO,172,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-1.21,-3.203,1.993,,0.076,E,B,0.35,-0.87,,,,HBH,-1.26667,0.175299,0.000296642,0.667971 kka2_1:2_P76T,kka2_1:2_76,Kka2,kka2_1:2,P00552,0.668048,NO,76,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.449,-2.904,1.455,,0.331,.,B,0.52,-0.41,0.345,,63.64,HOO,-1.662,0.295029,0.00625685,0.668048 kka2_1:2_G95H,kka2_1:2_95,Kka2,kka2_1:2,P00552,0.668073,NO,95,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-2.403,-4.673,2.27,,0.126,E,B,0.29,-0.74,0.359,,71.59,HOA,-2.198,0.295029,0.00743616,0.668073 beta-lactamase_D231H,beta-lactamase_231,TEM-1,beta-lactamase,P62593,0.668075,NO,231,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.816,-4.453,3.637,5.06651,,E,B,1.22,-1.06,0.319,,65.38,HAB,-0.994,0.221079,0.00107395,0.668075 beta-lactamase_L167Q,beta-lactamase_167,TEM-1,beta-lactamase,P62593,0.668075,NO,167,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.138,-4.038,2.9,5.13111,0.015,G,A,0.08,-0.63,0.4,,64.69,AHP,-1.30767,0.221079,0.00303566,0.668075 beta-lactamase_N272H,beta-lactamase_272,TEM-1,beta-lactamase,P62593,0.66812,NO,272,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-1.127,-4.188,3.061,5.37826,0.081,H,A,0.09,-0.97,1.468,,63.64,BPB,-1.56333,0.221079,0.00545371,0.66812 kka2_1:8_T187I,kka2_1:8_187,Kka2,kka2_1:8,P00552,0.668164,NO,187,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.273,-2.925,1.652,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.100394,0.00693073,0.668164 kka2_1:8_T187I,kka2_1:8_187,Kka2,kka2_1:8,P00552,0.668164,NO,187,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.273,-2.925,1.652,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.100394,0.00693073,0.668164 kka2_1:2_C31V,kka2_1:2_31,Kka2,kka2_1:2,P00552,0.668184,NO,31,C,V,CV,Special,Hydrophobic,5.07,5.60847,0.538465,192,121,117,-4,108.5,140,31.5,-2.246,-2.747,0.501,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.295029,0.00681582,0.668184 kka2_1:8_I207T,kka2_1:8_207,Kka2,kka2_1:8,P00552,0.668345,NO,207,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.175,-3.466,2.291,,0.293,,B,1.52,-1.12,1.306,,56.06,HHA,-1.07733,0.100394,0.00611824,0.668345 kka2_1:8_I207T,kka2_1:8_207,Kka2,kka2_1:8,P00552,0.668345,NO,207,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.175,-3.466,2.291,,0.293,,B,1.52,-1.12,1.306,,56.06,HHA,-1.07733,0.100394,0.00611824,0.668345 beta-lactamase_A15K,beta-lactamase_15,TEM-1,beta-lactamase,P62593,0.668357,NO,15,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.654,-3.412,1.758,,,,,,,31.998,31.998,93.01,HHH,-2.10833,0.221079,0.00248966,0.668357 beta-lactamase_2500_L188Y,beta-lactamase_2500_188,TEM-1,beta-lactamase_2500,P62593,0.66845,NO,188,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.166,-3.998,2.832,,,H,A,0.55,-0.3,17.865,17.865,60.14,PHB,-1.47033,0.361275,0.00295687,0.66845 kka2_1:4_H124R,kka2_1:4_124,Kka2,kka2_1:4,P00552,0.66852,NO,124,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-0.84,-3.511,2.671,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.168804,0.00211296,0.66852 kka2_1:1_R44L,kka2_1:1_44,Kka2,kka2_1:1,P00552,0.668534,NO,44,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.062,-2.371,0.309,,0.487,S,B,1.2,-0.35,2.717,,71.59,OBO,-1.80767,0.520039,0.00745043,0.668534 kka2_1:2_L94P,kka2_1:2_94,Kka2,kka2_1:2,P00552,0.668559,NO,94,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.618,-4.098,2.48,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.295029,0.00520888,0.668559 kka2_1:2_V185A,kka2_1:2_185,Kka2,kka2_1:2,P00552,0.668633,NO,185,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.045,-2.271,1.226,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.295029,0.00367031,0.668633 kka2_1:8_F240Q,kka2_1:8_240,Kka2,kka2_1:8,P00552,0.668674,NO,240,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-0.911,-4.376,3.465,,,H,A,1.62,-1.21,0.697,,50.38,BHH,-1.67267,0.100394,0.00552543,0.668674 kka2_1:8_F240Q,kka2_1:8_240,Kka2,kka2_1:8,P00552,0.668674,NO,240,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-0.911,-4.376,3.465,,,H,A,1.62,-1.21,0.697,,50.38,BHH,-1.67267,0.100394,0.00552543,0.668674 beta-lactamase_2500_R176Y,beta-lactamase_2500_176,TEM-1,beta-lactamase_2500,P62593,0.668683,NO,176,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-0.863,-4.162,3.299,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.361275,0.00105554,0.668683 kka2_1:1_D216E,kka2_1:1_216,Kka2,kka2_1:1,P00552,0.668683,NO,216,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.785,-2.854,2.069,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.520039,0.00229969,0.668683 Pab1_I152M,Pab1_152,Pab1,Pab1,P04147,0.668732,NO,152,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.345,-3.923,2.578,,0.165,E,B,1.23,-0.71,1.288,,71.4,AHH,-1.59433,0.175299,0.000740963,0.668732 kka2_1:1_Q136S,kka2_1:1_136,Kka2,kka2_1:1,P00552,0.668751,NO,136,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-3.021,-2.294,-0.727,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.520039,0.00624149,0.668751 kka2_1:2_L70C,kka2_1:2_70,Kka2,kka2_1:2,P00552,0.668856,NO,70,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.017,-4.768,3.751,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.295029,0.00411884,0.668856 kka2_1:2_R211S,kka2_1:2_211,Kka2,kka2_1:2,P00552,0.66891,NO,211,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-0.899,-3.475,2.576,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.295029,0.00204888,0.66891 beta-lactamase_L167P,beta-lactamase_167,TEM-1,beta-lactamase,P62593,0.668947,NO,167,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.138,-4.076,2.938,5.13111,0.015,G,A,0.08,-0.63,0.4,,64.69,AHP,-1.30767,0.221079,0.00303566,0.668947 beta-lactamase_0_A40I,beta-lactamase_0_40,TEM-1,beta-lactamase_0,P62593,0.669021,NO,40,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.402,-3.742,2.34,,0.155,S,B,0.46,0.21,0.783,,73.78,OHB,-1.40267,0.0500837,0.00490026,0.669021 kka2_1:4_L260P,kka2_1:4_260,Kka2,kka2_1:4,P00552,0.669022,NO,260,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.741,-4.133,3.392,,0.022,H,A,0.55,-0.52,,,,HHA,-0.845667,0.168804,0.0233782,0.669022 beta-lactamase_0_L111Q,beta-lactamase_0_111,TEM-1,beta-lactamase_0,P62593,0.669154,NO,111,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.76,-3.108,1.348,,0.328,T,A,0.55,0.93,1.966,,64.34,BHP,-1.884,0.0500837,0.00480671,0.669154 WW_domain_P174S,WW_domain_174,Yap65,WW_domain,P46937,0.669171,NO,174,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.035,-3.163,2.128,,,,,,,,,,HOH,-1.261,0.153962,0.000711366,0.669171 gb1_G235Q,gb1_235,gb1,gb1,P06654,0.669211,NO,235,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.419,-3.816,2.397,,,,,,,0.476,,11.83,POB,-1.86433,0.177985,0.00297491,0.669211 beta-lactamase_625_D231G,beta-lactamase_625_231,TEM-1,beta-lactamase_625,P62593,0.669303,NO,231,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.816,-3.182,2.366,,,E,B,0.75,-1.06,1.025,,65.38,HAB,-0.994,0.213352,0.00107395,0.669303 Pab1_F168A,Pab1_168,Pab1,Pab1,P04147,0.669332,NO,168,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.269,-3.173,1.904,,,,,,,0.789,,56.33,OHO,-1.10033,0.175299,0.00064061,0.669332 beta-lactamase_0_T131D,beta-lactamase_0_131,TEM-1,beta-lactamase_0,P62593,0.669344,NO,131,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.328,-3.605,2.277,,,H,A,0.22,-0.69,3.306,,67.48,PPH,-1.00867,0.0500837,0.00345886,0.669344 kka2_1:2_E182A,kka2_1:2_182,Kka2,kka2_1:2,P00552,0.669346,NO,182,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.516,-2.542,1.026,,0.326,,B,1.52,0.75,14.547,14.547,65.53,OAA,-1.806,0.295029,0.00641548,0.669346 Ubiquitin_L56A,Ubiquitin_56,Uba1,Ubiquitin,P0CG48,0.669355,NO,56,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.324,-2.508,1.184,4.83362,,T,A,,-0.91,,,,PHP,-1.60067,0.205827,0.000459465,0.669355 Ubiquitin_L67P,Ubiquitin_67,Uba1,Ubiquitin,P0CG48,0.669355,NO,67,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.435,-4.073,2.638,4.92156,,E,B,1.19,-1.02,6.371,6.371,30.8,PHB,-1.628,0.205827,0.000482727,0.669355 Ubiquitin_L73I,Ubiquitin_73,Uba1,Ubiquitin,P0CG48,0.669355,NO,73,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.801,-2.615,0.814,5.27116,0.518,,B,0.77,1,10.519,10.519,34.31,BHB,-1.858,0.205827,0.000710624,0.669355 Ubiquitin_T66Y,Ubiquitin_66,Uba1,Ubiquitin,P0CG48,0.669355,NO,66,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.58,-4.113,2.533,5.02702,0.46,E,B,0.8,-0.81,28.36,28.36,39.71,PPH,-1.51667,0.205827,0.000598414,0.669355 beta-lactamase_G114K,beta-lactamase_114,TEM-1,beta-lactamase,P62593,0.669435,NO,114,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.094,-3.566,2.472,4.92659,0.011,,p,0.77,0.35,2.148,,41.61,AOH,-1.43733,0.221079,0.00224919,0.669435 kka2_1:4_E169C,kka2_1:4_169,Kka2,kka2_1:4,P00552,0.669517,NO,169,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.996,-5.197,3.201,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.168804,0.00730086,0.669517 beta-lactamase_0_R59L,beta-lactamase_0_59,TEM-1,beta-lactamase_0,P62593,0.669581,NO,59,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.345,-3.484,2.139,,0.329,S,L,1.2,-0.09,2.919,,73.08,HBO,-2.24267,0.0500837,0.00318082,0.669581 beta-lactamase_2500_G76C,beta-lactamase_2500_76,TEM-1,beta-lactamase_2500,P62593,0.66984,NO,76,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.189,-4.823,3.634,,,H,A,0.29,-0.67,1.012,,67.83,OOH,-1.22267,0.361275,0.00476637,0.66984 kka2_1:4_Q219N,kka2_1:4_219,Kka2,kka2_1:4,P00552,0.669845,NO,219,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-0.93,-3.499,2.569,,0.088,H,A,0.64,-0.85,1.537,,50,HPA,-1.05167,0.168804,0.00237913,0.669845 kka2_1:1_T85S,kka2_1:1_85,Kka2,kka2_1:1,P00552,0.669889,NO,85,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.165,-2.241,0.076,,0.576,E,B,0.82,1.39,16.653,16.653,71.59,HPA,-2.10133,0.520039,0.00634493,0.669889 kka2_1:2_I29F,kka2_1:2_29,Kka2,kka2_1:2,P00552,0.669893,NO,29,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.692,-4.042,2.35,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.295029,0.00619521,0.669893 PSD95pdz3_E331K,PSD95pdz3_331,PSD95pdz3,PSD95pdz3,P31016,0.669915,NO,331,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.404,-2.689,1.285,5.86289,,,,,51.8889,,,,OAA,-1.22533,0.0758425,0.000950134,0.669915 kka2_1:1_E96A,kka2_1:1_96,Kka2,kka2_1:1,P00552,0.669931,NO,96,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.573,-1.097,-1.476,,0.476,,B,1.52,-0.65,1.254,,71.59,OAH,-2.143,0.520039,0.00369441,0.669931 kka2_1:4_D159G,kka2_1:4_159,Kka2,kka2_1:4,P00552,0.670007,NO,159,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.82,-2.148,1.328,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.168804,0.0030485,0.670007 beta-lactamase_39_I245Q,beta-lactamase_39_245,TEM-1,beta-lactamase_39,P62593,0.670009,NO,245,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.0495842,0.00391032,0.670009 kka2_1:1_R38S,kka2_1:1_38,Kka2,kka2_1:1,P00552,0.67006,NO,38,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.207,-3.563,2.356,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.520039,0.00372499,0.67006 beta-lactamase_625_P224L,beta-lactamase_625_224,TEM-1,beta-lactamase_625,P62593,0.670112,NO,224,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.893,-3.582,2.689,,0.383,,B,0.52,-0.3,1.35,,74.48,HOH,-1.26433,0.213352,0.00189564,0.670112 beta-lactamase_0_A40K,beta-lactamase_0_40,TEM-1,beta-lactamase_0,P62593,0.670131,NO,40,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.402,-3.658,2.256,,0.155,S,B,0.46,0.21,0.783,,73.78,OHB,-1.40267,0.0500837,0.00490026,0.670131 beta-lactamase_2500_L55E,beta-lactamase_2500_55,TEM-1,beta-lactamase_2500,P62593,0.670175,NO,55,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.86,-3.84,1.98,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.361275,0.00403741,0.670175 beta-lactamase_39_W208K,beta-lactamase_39_208,TEM-1,beta-lactamase_39,P62593,0.670189,NO,208,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-0.818,-3.907,3.089,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.0495842,0.00126609,0.670189 kka2_1:8_V113A,kka2_1:8_113,Kka2,kka2_1:8,P00552,0.670279,NO,113,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.233,-2.573,1.34,,0.008,H,A,1.48,-1.17,1.254,,52.27,BHP,-2.08367,0.100394,0.00650191,0.670279 kka2_1:8_V113A,kka2_1:8_113,Kka2,kka2_1:8,P00552,0.670279,NO,113,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.233,-2.573,1.34,,0.008,H,A,1.48,-1.17,1.254,,52.27,BHP,-2.08367,0.100394,0.00650191,0.670279 beta-lactamase_39_A230N,beta-lactamase_39_230,TEM-1,beta-lactamase_39,P62593,0.670355,NO,230,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.154,-3.731,2.577,,0.01,E,B,0.46,-1.17,1.171,,50,HHA,-1.079,0.0495842,0.00516841,0.670355 kka2_1:1_I196L,kka2_1:1_196,Kka2,kka2_1:1,P00552,0.670449,NO,196,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-2.115,-1.762,-0.353,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.520039,0.0107273,0.670449 gb1_G240K,gb1_240,gb1,gb1,P06654,0.670463,NO,240,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.921,-3.417,2.496,,,,,,,,,,BOA,-1.87867,0.177985,0.00270792,0.670463 gb1_K254M,gb1_254,gb1,gb1,P06654,0.670463,NO,254,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.748,-4.358,2.61,,,,,,,1.793,,37.28,ABH,-2.195,0.177985,0.00622711,0.670463 beta-lactamase_39_L150P,beta-lactamase_39_150,TEM-1,beta-lactamase_39,P62593,0.670504,NO,150,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.326,-4.037,2.711,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.0495842,0.00463171,0.670504 beta-lactamase_L146Q,beta-lactamase_146,TEM-1,beta-lactamase,P62593,0.670549,NO,146,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.462,-4.29,2.828,5.62483,0.007,H,A,1.3,-0.56,1.953,,64.69,AHP,-1.656,0.221079,0.00474542,0.670549 kka2_1:2_G99A,kka2_1:2_99,Kka2,kka2_1:2,P00552,0.67058,NO,99,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.596,-2.881,2.285,,0.368,S,g,0.29,-0.87,,,,OOP,-1.63067,0.295029,0.00186055,0.67058 kka2_1:4_R38T,kka2_1:4_38,Kka2,kka2_1:4,P00552,0.670694,NO,38,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.207,-3.514,2.307,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.168804,0.00372499,0.670694 kka2_1:1_L152K,kka2_1:1_152,Kka2,kka2_1:1,P00552,0.670713,NO,152,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.521,-3.615,2.094,,0.547,.,A,0.55,1.36,1.589,,63.64,OHH,-1.162,0.520039,0.00674868,0.670713 kka2_1:1_D23K,kka2_1:1_23,Kka2,kka2_1:1,P00552,0.670714,NO,23,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.459,-3.049,0.59,,0.695,E,B,0.75,-0.65,2.655,,65.53,HAH,-1.94033,0.520039,0.007195,0.670714 kka2_1:8_H124R,kka2_1:8_124,Kka2,kka2_1:8,P00552,0.670772,NO,124,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-0.84,-3.511,2.671,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.100394,0.00211296,0.670772 kka2_1:8_H124R,kka2_1:8_124,Kka2,kka2_1:8,P00552,0.670772,NO,124,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-0.84,-3.511,2.671,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.100394,0.00211296,0.670772 beta-lactamase_625_G114D,beta-lactamase_625_114,TEM-1,beta-lactamase_625,P62593,0.670802,NO,114,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.094,-3.551,2.457,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.213352,0.00224919,0.670802 kka2_1:1_Y244M,kka2_1:1_244,Kka2,kka2_1:1,P00552,0.670833,NO,244,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-0.775,-4.508,3.733,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.520039,0.00453187,0.670833 kka2_1:2_T187V,kka2_1:2_187,Kka2,kka2_1:2,P00552,0.670833,NO,187,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.273,-3.25,1.977,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.295029,0.00693073,0.670833 kka2_1:8_A117L,kka2_1:8_117,Kka2,kka2_1:8,P00552,0.670861,NO,117,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.828,-3.117,2.289,,,H,A,1.04,-0.78,0.755,,45.83,HHA,-1.79333,0.100394,0.00282984,0.670861 kka2_1:8_A117L,kka2_1:8_117,Kka2,kka2_1:8,P00552,0.670861,NO,117,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.828,-3.117,2.289,,,H,A,1.04,-0.78,0.755,,45.83,HHA,-1.79333,0.100394,0.00282984,0.670861 kka2_1:1_E59G,kka2_1:1_59,Kka2,kka2_1:1,P00552,0.6709,NO,59,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-0.952,-3.43,2.478,,0.187,.,L,1.04,0.62,2.648,,50.38,PAH,-1.53,0.520039,0.00280355,0.6709 kka2_1:1_Q155P,kka2_1:1_155,Kka2,kka2_1:1,P00552,0.670917,NO,155,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.606,-3.826,1.22,,0.525,T,A,0.4,1.49,4.415,,63.64,APA,-1.726,0.520039,0.00641853,0.670917 kka2_1:4_D183K,kka2_1:4_183,Kka2,kka2_1:4,P00552,0.671065,NO,183,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.204,-3.416,2.212,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.168804,0.00426304,0.671065 beta-lactamase_G279I,beta-lactamase_279,TEM-1,beta-lactamase,P62593,0.671086,NO,279,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.038,-4.027,2.989,4.53882,,H,A,0.46,-0.97,3.066,,62.59,HOH,-1.36467,0.221079,0.0192826,0.671086 beta-lactamase_E46R,beta-lactamase_46,TEM-1,beta-lactamase,P62593,0.671212,NO,46,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.94,-4.04,2.1,5.36461,0.021,E,B,1.51,0.14,0.373,,59.44,HAH,-2.079,0.221079,0.00427568,0.671212 beta-lactamase_39_D155H,beta-lactamase_39_155,TEM-1,beta-lactamase_39,P62593,0.671289,NO,155,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.889,-4.424,3.535,,0.049,,B,0.75,-0.9,3.208,,64.69,OAB,-1.62267,0.0495842,0.00135315,0.671289 kka2_1:8_M197K,kka2_1:8_197,Kka2,kka2_1:8,P00552,0.671309,NO,197,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.707,-3.81,2.103,,0.121,E,B,1.59,-1.19,4.408,,65.53,HHH,-1.847,0.100394,0.00921295,0.671309 kka2_1:8_M197K,kka2_1:8_197,Kka2,kka2_1:8,P00552,0.671309,NO,197,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.707,-3.81,2.103,,0.121,E,B,1.59,-1.19,4.408,,65.53,HHH,-1.847,0.100394,0.00921295,0.671309 beta-lactamase_0_D155N,beta-lactamase_0_155,TEM-1,beta-lactamase_0,P62593,0.671399,NO,155,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.889,-2.502,1.613,,0.049,,B,0.75,-0.9,16.833,16.833,64.69,OAB,-1.62267,0.0500837,0.00135315,0.671399 kka2_1:1_D180V,kka2_1:1_180,Kka2,kka2_1:1,P00552,0.671443,NO,180,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.416,-3.003,0.587,,1.03,S,a,0.75,1.5,1.534,,71.59,OAO,-2.02933,0.520039,0.00756412,0.671443 kka2_1:1_E142K,kka2_1:1_142,Kka2,kka2_1:1,P00552,0.671467,NO,142,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.221,-3.543,1.322,,0.471,H,A,1.52,0.85,3.626,,65.53,HAB,-2.08033,0.520039,0.00748883,0.671467 beta-lactamase_D83N,beta-lactamase_83,TEM-1,beta-lactamase,P62593,0.671485,NO,83,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.066,-3.355,2.289,5.40616,0.354,H,A,1.33,0.22,0.861,,48.95,HAH,-1.34733,0.221079,0.00205968,0.671485 kka2_1:8_G205C,kka2_1:8_205,Kka2,kka2_1:8,P00552,0.671488,NO,205,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.596,-5.115,4.519,,,E,b,0.75,-1.05,,,,POH,-1.09933,0.100394,0.00221855,0.671488 kka2_1:8_G205C,kka2_1:8_205,Kka2,kka2_1:8,P00552,0.671488,NO,205,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.596,-5.115,4.519,,,E,b,0.75,-1.05,,,,POH,-1.09933,0.100394,0.00221855,0.671488 beta-lactamase_2500_I244M,beta-lactamase_2500_244,TEM-1,beta-lactamase_2500,P62593,0.671492,NO,244,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.555,-4.138,2.583,,,E,B,0.48,-0.84,1.683,,77.62,OHH,-1.385,0.361275,0.00605379,0.671492 beta-lactamase_39_E119I,beta-lactamase_39_119,TEM-1,beta-lactamase_39,P62593,0.671507,NO,119,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.412,-4.096,2.684,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.0495842,0.00386966,0.671507 PSD95pdz3_G324S,PSD95pdz3_324,PSD95pdz3,PSD95pdz3,P31016,0.671561,NO,324,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.008,-2.842,1.834,4.98881,,,,,10.4525,,,,HOH,-1.293,0.0758425,0.00103462,0.671561 kka2_1:1_P128Q,kka2_1:1_128,Kka2,kka2_1:1,P00552,0.671606,NO,128,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.922,-4.314,2.392,,0.316,G,A,0.52,0.4,2.178,,56.06,AOH,-1.64733,0.520039,0.00774689,0.671606 beta-lactamase_2500_G39C,beta-lactamase_2500_39,TEM-1,beta-lactamase_2500,P62593,0.671613,NO,39,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.864,-5.191,3.327,,0.701,T,L,0.29,0.47,29.926,29.926,77.62,HOH,-1.53633,0.361275,0.00487611,0.671613 beta-lactamase_39_T107D,beta-lactamase_39_107,TEM-1,beta-lactamase_39,P62593,0.671642,NO,107,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.117,-3.478,2.361,,,G,A,0.22,-0.06,2.686,,67.83,HPA,-1.265,0.0495842,0.00239347,0.671642 beta-lactamase_G52P,beta-lactamase_52,TEM-1,beta-lactamase,P62593,0.671656,NO,52,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.149,-2.849,1.7,5.12093,0.299,,l,0.77,-0.04,2.103,,64.69,POB,-1.66267,0.221079,0.00340138,0.671656 PSD95pdz3_A376R,PSD95pdz3_376,PSD95pdz3,PSD95pdz3,P31016,0.67166,NO,376,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.307,-3.39,2.083,4.72134,,,,,17.108,,,,HHH,-1.49567,0.0758425,0.000341232,0.67166 beta-lactamase_2500_E108C,beta-lactamase_2500_108,TEM-1,beta-lactamase_2500,P62593,0.671686,NO,108,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.46,-5.208,3.748,,0.572,G,A,1.04,1.87,1.147,,72.73,PAB,-1.437,0.361275,0.00413372,0.671686 beta-lactamase_G263W,beta-lactamase_263,TEM-1,beta-lactamase,P62593,0.671722,NO,263,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-2.031,-5.5,3.469,5.09799,0.517,S,l,0.77,0.31,16.425,16.425,77.62,POP,-1.78267,0.221079,0.0110582,0.671722 kka2_1:1_L184M,kka2_1:1_184,Kka2,kka2_1:1,P00552,0.671723,NO,184,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.496,-3.37,1.874,,0.489,E,B,0.55,-0.06,19.127,19.127,63.26,AHH,-1.24833,0.520039,0.00518742,0.671723 beta-lactamase_156_V214D,beta-lactamase_156_214,TEM-1,beta-lactamase_156,P62593,0.671743,NO,214,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.299,-3.873,2.574,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.111618,0.00628442,0.671743 kka2_1:2_L165N,kka2_1:2_165,Kka2,kka2_1:2,P00552,0.671745,NO,165,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-2.453,-3.932,1.479,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.295029,0.00801161,0.671745 beta-lactamase_39_T107H,beta-lactamase_39_107,TEM-1,beta-lactamase_39,P62593,0.67178,NO,107,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.117,-4.67,3.553,,,G,A,0.22,-0.06,2.686,,67.83,HPA,-1.265,0.0495842,0.00239347,0.67178 kka2_1:8_T187N,kka2_1:8_187,Kka2,kka2_1:8,P00552,0.6718,NO,187,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.273,-3.75,2.477,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.100394,0.00693073,0.6718 kka2_1:8_T187N,kka2_1:8_187,Kka2,kka2_1:8,P00552,0.6718,NO,187,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.273,-3.75,2.477,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.100394,0.00693073,0.6718 kka2_1:4_M148I,kka2_1:4_148,Kka2,kka2_1:4,P00552,0.671848,NO,148,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.847,-2.616,0.769,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.168804,0.00982664,0.671848 kka2_1:2_R217S,kka2_1:2_217,Kka2,kka2_1:2,P00552,0.67189,NO,217,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.158,-3.548,2.39,,0.252,T,A,1.2,-0.59,0.381,,52.27,ABH,-1.127,0.295029,0.0047191,0.67189 beta-lactamase_156_I229N,beta-lactamase_156_229,TEM-1,beta-lactamase_156,P62593,0.671918,NO,229,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.267,-4.128,2.861,,0.083,E,B,0.48,-0.76,1.114,,50,HHH,-1.58767,0.111618,0.00477249,0.671918 Pab1_K156S,Pab1_156,Pab1,Pab1,P04147,0.671935,NO,156,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.083,-2.978,1.895,,0.406,E,B,1.82,-0.26,,,,PBH,-1.58167,0.175299,0.000316767,0.671935 kka2_1:4_D250Y,kka2_1:4_250,Kka2,kka2_1:4,P00552,0.671971,NO,250,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.015,-4.409,3.394,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.168804,0.0177103,0.671971 E1_Ubiquitin_H70C,E1_Ubiquitin_70,Uba1,E1_Ubiquitin,P0CG63,0.671972,NO,70,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-1.36,,,,0.05,E,B,0.61,-0.97,,,93.18,HBH,-1.146,0.18783,0.00206914,0.671972 kka2_1:8_R145M,kka2_1:8_145,Kka2,kka2_1:8,P00552,0.671986,NO,145,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.804,-4.748,2.944,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.100394,0.00846663,0.671986 kka2_1:8_R145M,kka2_1:8_145,Kka2,kka2_1:8,P00552,0.671986,NO,145,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.804,-4.748,2.944,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.100394,0.00846663,0.671986 kka2_1:1_D220Y,kka2_1:1_220,Kka2,kka2_1:1,P00552,0.672003,NO,220,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.787,-4.383,3.596,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.520039,0.00158066,0.672003 kka2_1:1_L165R,kka2_1:1_165,Kka2,kka2_1:1,P00552,0.672178,NO,165,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-2.453,-2.067,-0.386,,0.299,,B,1.59,1.12,2.47,,64.39,OHH,-1.90967,0.520039,0.00801161,0.672178 beta-lactamase_N272C,beta-lactamase_272,TEM-1,beta-lactamase,P62593,0.672189,NO,272,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-1.127,-5.181,4.054,5.37826,0.081,H,A,0.09,-0.97,1.468,,63.64,BPB,-1.56333,0.221079,0.00545371,0.672189 beta-lactamase_625_D231T,beta-lactamase_625_231,TEM-1,beta-lactamase_625,P62593,0.672227,NO,231,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.816,-3.447,2.631,,,E,B,0.75,-1.06,1.025,,65.38,HAB,-0.994,0.213352,0.00107395,0.672227 beta-lactamase_2500_A124V,beta-lactamase_2500_124,TEM-1,beta-lactamase_2500,P62593,0.672239,NO,124,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.181,-2.519,1.338,,,H,A,0.46,-0.9,0.314,,64.34,HHH,-1.152,0.361275,0.00481399,0.672239 beta-lactamase_625_Y95P,beta-lactamase_625_95,TEM-1,beta-lactamase_625,P62593,0.672271,NO,95,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-1.715,-4.285,2.57,,0.122,,b,0.21,-0.37,3.355,,77.62,BHP,-2.16167,0.213352,0.00479449,0.672271 beta-lactamase_E35V,beta-lactamase_35,TEM-1,beta-lactamase,P62593,0.6724,NO,35,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-0.869,-3.578,2.709,5.10723,0.15,H,A,0.52,0.21,1.081,,46.85,HAA,-1.88667,0.221079,0.00174441,0.6724 beta-lactamase_0_R63D,beta-lactamase_0_63,TEM-1,beta-lactamase_0,P62593,0.672405,NO,63,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-0.943,-3.762,2.819,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.0500837,0.00126938,0.672405 kka2_1:1_D23V,kka2_1:1_23,Kka2,kka2_1:1,P00552,0.672486,NO,23,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.459,-2.803,0.344,,0.695,E,B,0.75,-0.65,2.655,,65.53,HAH,-1.94033,0.520039,0.007195,0.672486 kka2_1:4_G201N,kka2_1:4_201,Kka2,kka2_1:4,P00552,0.672616,NO,201,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.56,-2.642,1.082,,0.149,T,l,0.29,-0.57,0.284,,52.65,POB,-1.92233,0.168804,0.00820117,0.672616 beta-lactamase_0_L136W,beta-lactamase_0_136,TEM-1,beta-lactamase_0,P62593,0.672638,NO,136,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.232,-5.281,4.049,,,H,A,0.55,-0.34,0.648,,48.95,HHH,-1.088,0.0500837,0.00442304,0.672638 kka2_1:1_G151N,kka2_1:1_151,Kka2,kka2_1:1,P00552,0.672682,NO,151,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.873,-2.707,1.834,,0.678,T,l,0.29,1.36,0.226,,49.62,HOH,-1.11433,0.520039,0.00339918,0.672682 beta-lactamase_0_L120I,beta-lactamase_0_120,TEM-1,beta-lactamase_0,P62593,0.672729,NO,120,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.044,-2.541,1.497,,,H,A,0.55,-1.13,1.2,,64.69,AHO,-1.13633,0.0500837,0.00143563,0.672729 beta-lactamase_2500_A77E,beta-lactamase_2500_77,TEM-1,beta-lactamase_2500,P62593,0.672746,NO,77,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.234,-3.61,2.376,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.361275,0.00282362,0.672746 PSD95pdz3_L360P,PSD95pdz3_360,PSD95pdz3,PSD95pdz3,P31016,0.672776,NO,360,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.431,-3.785,2.354,5.09284,,,,,14.2425,1.419,,86.88,HHP,-1.52667,0.0758425,0.000770471,0.672776 kka2_1:8_T225D,kka2_1:8_225,Kka2,kka2_1:8,P00552,0.672959,NO,225,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.393,-3.922,1.529,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.100394,0.0113598,0.672959 kka2_1:8_T225D,kka2_1:8_225,Kka2,kka2_1:8,P00552,0.672959,NO,225,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.393,-3.922,1.529,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.100394,0.0113598,0.672959 kka2_1:2_Q219K,kka2_1:2_219,Kka2,kka2_1:2,P00552,0.672977,NO,219,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-0.93,-3.033,2.103,,0.088,H,A,0.4,-0.85,1.917,,50,HPA,-1.05167,0.295029,0.00237913,0.672977 WW_domain_P174L,WW_domain_174,Yap65,WW_domain,P46937,0.67302,NO,174,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.035,-3.36,2.325,,,,,,,,,,HOH,-1.261,0.153962,0.000711366,0.67302 PSD95pdz3_A347I,PSD95pdz3_347,PSD95pdz3,PSD95pdz3,P31016,0.673025,NO,347,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.307,-3.242,1.935,4.89689,,,,,15.176,,,,OHA,-1.269,0.0758425,0.00074525,0.673025 WW_domain_T198E,WW_domain_198,Yap65,WW_domain,P46937,0.673029,NO,198,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.451,-3.412,1.961,5.14348,,,,,,3.158,,70.04,PPH,-1.513,0.153962,0.00224534,0.673029 kka2_1:1_A168L,kka2_1:1_168,Kka2,kka2_1:1,P00552,0.673056,NO,168,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.989,-3.651,1.662,,0.67,H,A,0.46,0.15,25.546,25.546,64.39,OHA,-2.12933,0.520039,0.00806773,0.673056 kka2_1:8_D159M,kka2_1:8_159,Kka2,kka2_1:8,P00552,0.673111,NO,159,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.82,-4.992,4.172,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.100394,0.0030485,0.673111 kka2_1:8_D159M,kka2_1:8_159,Kka2,kka2_1:8,P00552,0.673111,NO,159,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.82,-4.992,4.172,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.100394,0.0030485,0.673111 kka2_1:4_L193P,kka2_1:4_193,Kka2,kka2_1:4,P00552,0.673127,NO,193,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.983,-2.872,1.889,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.168804,0.00480179,0.673127 kka2_1:2_T28W,kka2_1:2_28,Kka2,kka2_1:2,P00552,0.673179,NO,28,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.883,-5.518,3.635,,0.353,S,B,0.22,2.02,2.655,,63.64,PPH,-1.74467,0.295029,0.00743084,0.673179 beta-lactamase_625_I244W,beta-lactamase_625_244,TEM-1,beta-lactamase_625,P62593,0.673265,NO,244,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.555,-5.375,3.82,,,E,B,0.48,-0.84,2.061,,77.62,OHH,-1.385,0.213352,0.00605379,0.673265 beta-lactamase_39_T158D,beta-lactamase_39_158,TEM-1,beta-lactamase_39,P62593,0.673428,NO,158,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.116,-3.478,2.362,,0.036,,B,0.22,-0.85,2.755,,69.58,HPB,-1.269,0.0495842,0.00341825,0.673428 beta-lactamase_0_R220A,beta-lactamase_0_220,TEM-1,beta-lactamase_0,P62593,0.67345,NO,220,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-0.942,-2.357,1.415,,0.295,I,A,1.2,-0.76,21.573,21.573,74.48,HBP,-1.33633,0.0500837,0.00232421,0.67345 beta-lactamase_0_E195V,beta-lactamase_0_195,TEM-1,beta-lactamase_0,P62593,0.673451,NO,195,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.186,-3.798,1.612,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.0500837,0.00496565,0.673451 kka2_1:1_T51N,kka2_1:1_51,Kka2,kka2_1:1,P00552,0.673454,NO,51,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.199,-3.862,1.663,,0.05,E,B,0.22,-0.05,3.056,,63.64,BPA,-1.76767,0.520039,0.00628861,0.673454 kka2_1:4_A144T,kka2_1:4_144,Kka2,kka2_1:4,P00552,0.673464,NO,144,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.859,-3.269,2.41,,,H,A,0.46,0.21,6.844,,52.65,BHB,-1.72933,0.168804,0.00231095,0.673464 kka2_1:4_W15Q,kka2_1:4_15,Kka2,kka2_1:4,P00552,0.673509,NO,15,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-1.392,-4.279,2.887,,0.01,G,A,0.47,0.15,0.943,,52.27,HHH,-2.10533,0.168804,0.00585505,0.673509 beta-lactamase_39_M153P,beta-lactamase_39_153,TEM-1,beta-lactamase_39,P62593,0.673549,NO,153,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-3.193,-4.07,0.877,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.0495842,0.00509109,0.673549 beta-lactamase_156_D83W,beta-lactamase_156_83,TEM-1,beta-lactamase_156,P62593,0.673571,NO,83,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.066,-5.509,4.443,,0.354,H,A,0.75,0.22,1.281,,48.95,HAH,-1.34733,0.111618,0.00205968,0.673571 beta-lactamase_0_P25M,beta-lactamase_0_25,TEM-1,beta-lactamase_0,P62593,0.673572,NO,25,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.526,-4.708,3.182,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.0500837,0.00347571,0.673572 beta-lactamase_0_A40R,beta-lactamase_0_40,TEM-1,beta-lactamase_0,P62593,0.673603,NO,40,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.402,-3.924,2.522,,0.155,S,B,0.46,0.21,0.783,,73.78,OHB,-1.40267,0.0500837,0.00490026,0.673603 beta-lactamase_0_S201K,beta-lactamase_0_201,TEM-1,beta-lactamase_0,P62593,0.67361,NO,201,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.183,-3.387,2.204,,0.064,H,A,0.27,-0.07,3.54,,64.69,HPB,-1.451,0.0500837,0.00198815,0.67361 kka2_1:8_N195T,kka2_1:8_195,Kka2,kka2_1:8,P00552,0.673626,NO,195,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-0.836,-3.268,2.432,,0.037,G,A,0.43,-1.36,1.108,,48.11,OPH,-1.26567,0.100394,0.00276134,0.673626 kka2_1:8_N195T,kka2_1:8_195,Kka2,kka2_1:8,P00552,0.673626,NO,195,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-0.836,-3.268,2.432,,0.037,G,A,0.43,-1.36,1.108,,48.11,OPH,-1.26567,0.100394,0.00276134,0.673626 beta-lactamase_625_L135S,beta-lactamase_625_135,TEM-1,beta-lactamase_625,P62593,0.673649,NO,135,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.002,-3.64,2.638,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.213352,0.00244423,0.673649 beta-lactamase_156_G236Q,beta-lactamase_156_236,TEM-1,beta-lactamase_156,P62593,0.673652,NO,236,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.784,-4.093,3.309,,0.241,,b,0.29,-0.59,1.883,,64.69,HOO,-1.025,0.111618,0.00162372,0.673652 beta-lactamase_0_T107W,beta-lactamase_0_107,TEM-1,beta-lactamase_0,P62593,0.673662,NO,107,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.117,-5.223,4.106,,,G,A,0.22,-0.06,3.73,,67.83,HPA,-1.265,0.0500837,0.00239347,0.673662 beta-lactamase_D48L,beta-lactamase_48,TEM-1,beta-lactamase,P62593,0.673715,NO,48,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.101,-3.744,2.643,4.89966,0.189,E,B,0.23,0.21,1.281,,50.35,HAH,-1.62467,0.221079,0.0027273,0.673715 PSD95pdz3_A376P,PSD95pdz3_376,PSD95pdz3,PSD95pdz3,P31016,0.673717,NO,376,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.307,-3.336,2.029,4.72134,,,,,17.108,,,,HHH,-1.49567,0.0758425,0.000341232,0.673717 kka2_1:2_Q219L,kka2_1:2_219,Kka2,kka2_1:2,P00552,0.673732,NO,219,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-0.93,-3.41,2.48,,0.088,H,A,0.4,-0.85,1.917,,50,HPA,-1.05167,0.295029,0.00237913,0.673732 PSD95pdz3_D348V,PSD95pdz3_348,PSD95pdz3,PSD95pdz3,P31016,0.673754,NO,348,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.264,-3.435,2.171,5.02473,,,,,16.8925,,,,HAH,-1.306,0.0758425,0.000731866,0.673754 beta-lactamase_625_L100R,beta-lactamase_625_100,TEM-1,beta-lactamase_625,P62593,0.673979,NO,100,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.218,-4.123,2.905,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.213352,0.00413885,0.673979 beta-lactamase_2500_G216D,beta-lactamase_2500_216,TEM-1,beta-lactamase_2500,P62593,0.674001,NO,216,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.477,-1.722,0.245,,0.437,I,A,0.29,-0.58,1.983,,74.48,HOO,-1.68067,0.361275,0.00639568,0.674001 beta-lactamase_156_L160D,beta-lactamase_156_160,TEM-1,beta-lactamase_156,P62593,0.674051,NO,160,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.977,-4.122,3.145,,0.022,,B,0.55,-0.6,1.095,,44.41,BHA,-0.936,0.111618,0.00193775,0.674051 beta-lactamase_0_L89K,beta-lactamase_0_89,TEM-1,beta-lactamase_0,P62593,0.674068,NO,89,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.096,-3.669,2.573,,0.168,T,A,0.55,0.63,2.373,,64.34,PHO,-1.75767,0.0500837,0.00207068,0.674068 kka2_1:4_L94P,kka2_1:4_94,Kka2,kka2_1:4,P00552,0.674104,NO,94,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.618,-4.098,2.48,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.168804,0.00520888,0.674104 gb1_L238Y,gb1_238,gb1,gb1,P06654,0.674162,NO,238,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-2.98,-3.328,0.348,,,,,,,0.504,,45.54,PHB,-2.58633,0.177985,0.00205885,0.674162 beta-lactamase_625_D83H,beta-lactamase_625_83,TEM-1,beta-lactamase_625,P62593,0.674167,NO,83,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.066,-4.503,3.437,,0.354,H,A,0.75,0.22,0.239,,48.95,HAH,-1.34733,0.213352,0.00205968,0.674167 beta-lactamase_625_R242Q,beta-lactamase_625_242,TEM-1,beta-lactamase_625,P62593,0.674275,NO,242,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.213352,0.00452879,0.674275 beta-lactamase_G85I,beta-lactamase_85,TEM-1,beta-lactamase,P62593,0.674305,NO,85,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.011,-4.226,3.215,5.58951,0.805,T,l,0.23,1.7,1.468,,63.64,HOP,-1.68733,0.221079,0.00252173,0.674305 kka2_1:4_R140K,kka2_1:4_140,Kka2,kka2_1:4,P00552,0.674312,NO,140,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.351,-2.269,0.918,,0.12,H,A,1.2,0.2,2.561,,53.03,BBH,-1.885,0.168804,0.00430167,0.674312 beta-lactamase_39_C121F,beta-lactamase_39_121,TEM-1,beta-lactamase_39,P62593,0.674333,NO,121,C,F,CF,Special,Hydrophobic,5.07,3.32051,-1.74949,205,121,165,44,108.5,189.9,81.4,-0.953,-4.116,3.163,,,H,A,0.46,-0.81,7.644,,63.29,HOP,-1.46767,0.0495842,0.000744322,0.674333 Pab1_S155D,Pab1_155,Pab1,Pab1,P04147,0.674342,NO,155,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.039,-3.621,1.582,,,,,,,,,,PPB,-1.42267,0.175299,0.00208179,0.674342 kka2_1:2_A137T,kka2_1:2_137,Kka2,kka2_1:2,P00552,0.674381,NO,137,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.156,-3.52,1.364,,0.029,H,A,0.46,0.34,1.323,,63.26,PHB,-2.559,0.295029,0.00515054,0.674381 beta-lactamase_2500_V31A,beta-lactamase_2500_31,TEM-1,beta-lactamase_2500,P62593,0.674382,NO,31,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.822,-2.265,0.443,,,H,A,0.44,-0.46,0.955,,73.78,BHB,-2.03767,0.361275,0.00478065,0.674382 beta-lactamase_D212R,beta-lactamase_212,TEM-1,beta-lactamase,P62593,0.674417,NO,212,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.624,-3.921,2.297,4.9705,0.037,,b,1.3,-0.58,12.482,,74.48,HAB,-1.77667,0.221079,0.00644302,0.674417 kka2_1:4_E182V,kka2_1:4_182,Kka2,kka2_1:4,P00552,0.674468,NO,182,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.516,-3.667,2.151,,0.326,.,B,1.04,0.75,4.755,,65.53,OAA,-1.806,0.168804,0.00641548,0.674468 kka2_1:4_G74Y,kka2_1:4_74,Kka2,kka2_1:4,P00552,0.674514,NO,74,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.18,-4.468,3.288,,0.621,T,l,0.75,0.2,1.032,,64.39,POH,-1.91667,0.168804,0.00587035,0.674514 kka2_1:8_F263S,kka2_1:8_263,Kka2,kka2_1:8,P00552,0.674645,NO,263,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-0.911,-3.673,2.762,,0.006,G,A,1.62,-0.12,0.928,,45.83,AHH,-0.92,0.100394,0.0172454,0.674645 kka2_1:8_F263S,kka2_1:8_263,Kka2,kka2_1:8,P00552,0.674645,NO,263,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-0.911,-3.673,2.762,,0.006,G,A,1.62,-0.12,0.928,,45.83,AHH,-0.92,0.100394,0.0172454,0.674645 beta-lactamase_2500_M67Q,beta-lactamase_2500_67,TEM-1,beta-lactamase_2500,P62593,0.674761,NO,67,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-2.231,-4.09,1.859,,0.006,G,P,0.55,-0.81,2.653,,65.03,HHP,-1.502,0.361275,0.00409753,0.674761 beta-lactamase_0_D231F,beta-lactamase_0_231,TEM-1,beta-lactamase_0,P62593,0.674794,NO,231,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.816,-4.318,3.502,,,E,B,0.75,-1.06,4.975,,65.38,HAB,-0.994,0.0500837,0.00107395,0.674794 kka2_1:8_R211C,kka2_1:8_211,Kka2,kka2_1:8,P00552,0.674822,NO,211,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-0.899,-5.114,4.215,,0.12,T,a,0.16,-0.39,0.615,,49.62,OBH,-0.966,0.100394,0.00204888,0.674822 kka2_1:8_R211C,kka2_1:8_211,Kka2,kka2_1:8,P00552,0.674822,NO,211,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-0.899,-5.114,4.215,,0.12,T,a,0.16,-0.39,0.615,,49.62,OBH,-0.966,0.100394,0.00204888,0.674822 WW_domain_L190Q,WW_domain_190,Yap65,WW_domain,P46937,0.674923,NO,190,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.404,-4.001,2.597,5.53598,,,,,,0.645,,56.55,HHP,-1.51833,0.153962,0.00249186,0.674923 beta-lactamase_625_L28P,beta-lactamase_625_28,TEM-1,beta-lactamase_625,P62593,0.674975,NO,28,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.579,-4.027,2.448,,0.277,H,A,0.55,-0.16,2.716,,93.01,PHH,-2.11333,0.213352,0.00359321,0.674975 kka2_1:2_D157E,kka2_1:2_157,Kka2,kka2_1:2,P00552,0.674995,NO,157,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.993,-2.48,1.487,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.295029,0.0042313,0.674995 beta-lactamase_0_I125R,beta-lactamase_0_125,TEM-1,beta-lactamase_0,P62593,0.675188,NO,125,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.441,-4.126,2.685,,,H,A,0.48,-0.7,1.874,,63.29,HHP,-1.248,0.0500837,0.00383964,0.675188 beta-lactamase_625_L197G,beta-lactamase_625_197,TEM-1,beta-lactamase_625,P62593,0.675285,NO,197,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.853,-3.681,2.828,,0.007,S,B,0.55,0.33,1.756,,60.14,HHP,-1.833,0.213352,0.00144602,0.675285 gb1_G235D,gb1_235,gb1,gb1,P06654,0.675377,NO,235,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.419,-3.28,1.861,,,,,,,0.476,,11.83,POB,-1.86433,0.177985,0.00297491,0.675377 gb1_L238D,gb1_238,gb1,gb1,P06654,0.675377,NO,238,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-2.98,-3.396,0.416,,,,,,,0.504,,45.54,PHB,-2.58633,0.177985,0.00205885,0.675377 beta-lactamase_0_S128G,beta-lactamase_0_128,TEM-1,beta-lactamase_0,P62593,0.67539,NO,128,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-0.84,-2.908,2.068,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.0500837,0.00071483,0.67539 kka2_1:4_P132H,kka2_1:4_132,Kka2,kka2_1:4,P00552,0.675399,NO,132,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.775,-4.706,3.931,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.168804,0.0018489,0.675399 kka2_1:1_L184P,kka2_1:1_184,Kka2,kka2_1:1,P00552,0.675481,NO,184,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.496,-2.724,1.228,,0.489,E,B,0.55,-0.06,19.127,19.127,63.26,AHH,-1.24833,0.520039,0.00518742,0.675481 E1_Ubiquitin_L73P,E1_Ubiquitin_73,Uba1,E1_Ubiquitin,P0CG63,0.675508,NO,73,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.039,-3.922,2.883,,0.518,,B,1.3,1,,,,BHB,-1.175,0.18783,0.00111236,0.675508 kka2_1:1_G151V,kka2_1:1_151,Kka2,kka2_1:1,P00552,0.675568,NO,151,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.873,-3.846,2.973,,0.678,T,l,0.29,1.36,0.226,,49.62,HOH,-1.11433,0.520039,0.00339918,0.675568 PSD95pdz3_F337E,PSD95pdz3_337,PSD95pdz3,PSD95pdz3,P31016,0.675574,NO,337,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.524,-3.572,2.048,5.22838,,,,,13.4936,,,,HHH,-1.59467,0.0758425,0.000875287,0.675574 kka2_1:1_A172S,kka2_1:1_172,Kka2,kka2_1:1,P00552,0.675576,NO,172,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.757,-2.625,0.868,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.520039,0.0079265,0.675576 beta-lactamase_156_W208V,beta-lactamase_156_208,TEM-1,beta-lactamase_156,P62593,0.675593,NO,208,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-0.818,-3.754,2.936,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.111618,0.00126609,0.675593 kka2_1:4_F256V,kka2_1:4_256,Kka2,kka2_1:4,P00552,0.675623,NO,256,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.49,-3.528,2.038,,,H,A,0.58,-0.78,1.653,,53.03,HHH,-1.423,0.168804,0.0132841,0.675623 kka2_1:2_R253H,kka2_1:2_253,Kka2,kka2_1:2,P00552,0.675678,NO,253,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.356,-4.521,3.165,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.295029,0.0144195,0.675678 beta-lactamase_A215R,beta-lactamase_215,TEM-1,beta-lactamase,P62593,0.67574,NO,215,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.503,-3.862,2.359,4.82164,,,a,0.75,-0.93,3.583,,74.48,HHO,-1.42633,0.221079,0.00544007,0.67574 kka2_1:2_P109T,kka2_1:2_109,Kka2,kka2_1:2,P00552,0.675758,NO,109,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.412,-2.893,1.481,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.295029,0.0070929,0.675758 kka2_1:1_D118V,kka2_1:1_118,Kka2,kka2_1:1,P00552,0.675857,NO,118,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.07,-3.108,1.038,,0.61,H,A,0.75,-0.05,13.434,13.434,64.39,HAH,-1.32367,0.520039,0.0067852,0.675857 kka2_1:4_S104I,kka2_1:4_104,Kka2,kka2_1:4,P00552,0.675978,NO,104,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.436,-3.864,2.428,,0.536,T,A,0.27,-1.11,0.357,,63.64,HPP,-1.91433,0.168804,0.00555207,0.675978 kka2_1:8_H162K,kka2_1:8_162,Kka2,kka2_1:8,P00552,0.676053,NO,162,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-2.319,-3.151,0.832,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.100394,0.00616145,0.676053 kka2_1:8_H162K,kka2_1:8_162,Kka2,kka2_1:8,P00552,0.676053,NO,162,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-2.319,-3.151,0.832,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.100394,0.00616145,0.676053 beta-lactamase_156_L284K,beta-lactamase_156_284,TEM-1,beta-lactamase_156,P62593,0.676067,NO,284,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.981,-3.504,1.523,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.111618,0.0686156,0.676067 WW_domain_K181V,WW_domain_181,Yap65,WW_domain,P46937,0.676087,NO,181,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.35,-3.299,1.949,5.0864,,,,,,0.176,,15.87,HBP,-1.247,0.153962,0.0033022,0.676087 beta-lactamase_A246H,beta-lactamase_246,TEM-1,beta-lactamase,P62593,0.676098,NO,246,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.121,-4.964,2.843,4.78979,0.01,E,B,0.52,-1.01,1.26,,73.78,HHH,-1.55633,0.221079,0.00569458,0.676098 beta-lactamase_E35M,beta-lactamase_35,TEM-1,beta-lactamase,P62593,0.676098,NO,35,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-0.869,-4.754,3.885,5.10723,0.15,H,A,0.52,0.21,1.081,,46.85,HAA,-1.88667,0.221079,0.00174441,0.676098 beta-lactamase_F17E,beta-lactamase_17,TEM-1,beta-lactamase,P62593,0.676098,NO,17,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-2.337,-3.761,1.424,,,,,,,2.192,,67.83,HHO,-2.17733,0.221079,0.00216499,0.676098 beta-lactamase_G142H,beta-lactamase_142,TEM-1,beta-lactamase,P62593,0.676098,NO,142,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.707,-4.678,3.971,4.55474,0.034,,p,0.77,-0.64,1.947,,64.69,OOO,-0.834,0.221079,0.00060149,0.676098 beta-lactamase_I45E,beta-lactamase_45,TEM-1,beta-lactamase,P62593,0.676098,NO,45,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-2.421,-3.737,1.316,5.31505,,E,B,1,-0.3,2.256,,77.62,HHA,-2.30267,0.221079,0.00452842,0.676098 beta-lactamase_L100H,beta-lactamase_100,TEM-1,beta-lactamase,P62593,0.676098,NO,100,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.218,-4.855,3.637,5.60291,0.343,,B,1.3,0.13,1.173,,63.29,AHH,-1.23467,0.221079,0.00413885,0.676098 beta-lactamase_L55D,beta-lactamase_55,TEM-1,beta-lactamase,P62593,0.676098,NO,55,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.86,-4.094,2.234,,0.372,E,A,1.07,-0.36,1.423,,63.99,HHA,-2.247,0.221079,0.00403741,0.676098 beta-lactamase_156_L49D,beta-lactamase_156_49,TEM-1,beta-lactamase_156,P62593,0.676117,NO,49,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.897,-3.778,1.881,,0.131,T,A,0.55,0.04,3.112,,64.69,AHP,-1.99233,0.111618,0.00401477,0.676117 beta-lactamase_39_S233E,beta-lactamase_39_233,TEM-1,beta-lactamase_39,P62593,0.676306,NO,233,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.886,-3.479,1.593,,0.016,E,B,0.27,-1.01,5.361,,77.62,BPO,-1.17267,0.0495842,0.00311415,0.676306 Pab1_H172C,Pab1_172,Pab1,Pab1,P04147,0.676376,NO,172,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-1.21,-4.904,3.694,,0.076,E,B,0.35,-0.87,,,,HBH,-1.26667,0.175299,0.000296642,0.676376 beta-lactamase_0_P255K,beta-lactamase_0_255,TEM-1,beta-lactamase_0,P62593,0.676387,NO,255,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.0500837,0.00499612,0.676387 kka2_1:1_Q27M,kka2_1:1_27,Kka2,kka2_1:1,P00552,0.676395,NO,27,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-1.659,-3.318,1.659,,0.608,.,A,0.64,0.71,0.521,,65.53,PPP,-1.90733,0.520039,0.00595365,0.676395 kka2_1:2_L223P,kka2_1:2_223,Kka2,kka2_1:2,P00552,0.676453,NO,223,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.861,-4.178,3.317,,,H,A,0.55,-1.24,0.266,,50,HHH,-0.854333,0.295029,0.00253574,0.676453 beta-lactamase_0_A246Q,beta-lactamase_0_246,TEM-1,beta-lactamase_0,P62593,0.676474,NO,246,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.121,-4.263,2.142,,0.01,E,B,0.46,-1.01,1.201,,73.78,HHH,-1.55633,0.0500837,0.00569458,0.676474 beta-lactamase_625_T147W,beta-lactamase_625_147,TEM-1,beta-lactamase_625,P62593,0.676494,NO,147,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.149,-5.268,4.119,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.213352,0.00226017,0.676494 kka2_1:4_L107V,kka2_1:4_107,Kka2,kka2_1:4,P00552,0.676511,NO,107,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.238,-2.216,0.978,,0.197,.,B,0.55,-1.1,0.398,,71.59,BHH,-2.143,0.168804,0.00561937,0.676511 WW_domain_A180D,WW_domain_180,Yap65,WW_domain,P46937,0.676551,NO,180,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.242,-3.464,2.222,6.02829,,,,,,0.627,,23.61,HHB,-1.37767,0.153962,0.00413929,0.676551 beta-lactamase_2500_S256P,beta-lactamase_2500_256,TEM-1,beta-lactamase_2500,P62593,0.676578,NO,256,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.361275,0.00710634,0.676578 gb1_L233E,gb1_233,gb1,gb1,P06654,0.676582,NO,233,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-2.678,-3.127,0.449,,,,,,,0.822,,45.54,HHP,-2.30267,0.177985,0.00266958,0.676582 kka2_1:2_E161H,kka2_1:2_161,Kka2,kka2_1:2,P00552,0.676583,NO,161,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.581,-4.674,3.093,,0.829,G,A,1.52,2.24,1.612,,92.05,AAB,-1.861,0.295029,0.00760103,0.676583 kka2_1:8_I228S,kka2_1:8_228,Kka2,kka2_1:8,P00552,0.676631,NO,228,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.142,-3.711,2.569,,,H,A,1.52,-1.2,1.521,,71.59,AHH,-1.54633,0.100394,0.00458834,0.676631 kka2_1:8_I228S,kka2_1:8_228,Kka2,kka2_1:8,P00552,0.676631,NO,228,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.142,-3.711,2.569,,,H,A,1.52,-1.2,1.521,,71.59,AHH,-1.54633,0.100394,0.00458834,0.676631 beta-lactamase_0_A235D,beta-lactamase_0_235,TEM-1,beta-lactamase_0,P62593,0.676671,NO,235,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.266,-3.668,2.402,,0.32,E,B,0.46,-0.86,2.261,,50,OHO,-0.89,0.0500837,0.00493474,0.676671 kka2_1:1_E182T,kka2_1:1_182,Kka2,kka2_1:1,P00552,0.676704,NO,182,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.516,-2.525,1.009,,0.326,,B,1.52,0.75,14.547,14.547,65.53,OAA,-1.806,0.520039,0.00641548,0.676704 beta-lactamase_2500_F58C,beta-lactamase_2500_58,TEM-1,beta-lactamase_2500,P62593,0.676715,NO,58,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-2.914,-5.093,2.179,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.361275,0.00523369,0.676715 beta-lactamase_0_D155F,beta-lactamase_0_155,TEM-1,beta-lactamase_0,P62593,0.676721,NO,155,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.889,-4.341,3.452,,0.049,,B,0.75,-0.9,16.833,16.833,64.69,OAB,-1.62267,0.0500837,0.00135315,0.676721 kka2_1:1_F20C,kka2_1:1_20,Kka2,kka2_1:1,P00552,0.676754,NO,20,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-3.354,-5.001,1.647,,0.935,T,B,0.58,-0.41,1.657,,92.05,HHO,-1.992,0.520039,0.00701744,0.676754 kka2_1:8_H188D,kka2_1:8_188,Kka2,kka2_1:8,P00552,0.676894,NO,188,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-0.913,-3.495,2.582,,0.006,,A,0.87,-1.02,1.241,,47.73,PBO,-0.927333,0.100394,0.00273139,0.676894 kka2_1:8_H188D,kka2_1:8_188,Kka2,kka2_1:8,P00552,0.676894,NO,188,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-0.913,-3.495,2.582,,0.006,,A,0.87,-1.02,1.241,,47.73,PBO,-0.927333,0.100394,0.00273139,0.676894 Pab1_S154A,Pab1_154,Pab1,Pab1,P04147,0.676964,NO,154,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.146,-2.445,1.299,,0.208,E,B,0.1,-0.75,,,,HPP,-1.408,0.175299,0.000319331,0.676964 kka2_1:8_F240S,kka2_1:8_240,Kka2,kka2_1:8,P00552,0.676982,NO,240,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-0.911,-3.673,2.762,,,H,A,1.62,-1.21,0.697,,50.38,BHH,-1.67267,0.100394,0.00552543,0.676982 kka2_1:8_F240S,kka2_1:8_240,Kka2,kka2_1:8,P00552,0.676982,NO,240,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-0.911,-3.673,2.762,,,H,A,1.62,-1.21,0.697,,50.38,BHH,-1.67267,0.100394,0.00552543,0.676982 WW_domain_R187G,WW_domain_187,Yap65,WW_domain,P46937,0.676984,NO,187,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.402,-3.198,1.796,5.05189,,,,,,3.431,,78.57,PBH,-1.362,0.153962,0.00171149,0.676984 hsp90_F583S,hsp90_583,hsp90,hsp90,P02829,0.677022,NO,583,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-3.22,-2.764,0,5.28185,1.112,S,l,1.1,0.87,,,,PHO,-3.003,0.368192,0.000222939,0.677022 Pab1_Y197D,Pab1_197,Pab1,Pab1,P04147,0.677148,NO,197,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-1.345,-3.832,2.487,,,,,,,0.891,,80.42,HHH,-1.41767,0.175299,0.00302474,0.677148 kka2_1:1_L260P,kka2_1:1_260,Kka2,kka2_1:1,P00552,0.677206,NO,260,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.741,-4.133,3.392,,0.022,H,A,0.55,-0.52,,,,HHA,-0.845667,0.520039,0.0233782,0.677206 beta-lactamase_2500_F149Q,beta-lactamase_2500_149,TEM-1,beta-lactamase_2500,P62593,0.677246,NO,149,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.299,-4.204,2.905,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.361275,0.00418462,0.677246 beta-lactamase_0_Y95H,beta-lactamase_0_95,TEM-1,beta-lactamase_0,P62593,0.677297,NO,95,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-1.715,-3.182,1.467,,0.122,,b,0.21,-0.37,2.914,,77.62,BHP,-2.16167,0.0500837,0.00479449,0.677297 beta-lactamase_0_F70K,beta-lactamase_0_70,TEM-1,beta-lactamase_0,P62593,0.677353,NO,70,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.169,-3.812,2.643,,,H,A,0.58,-1.34,2.153,,63.99,PHB,-0.980667,0.0500837,0.00193499,0.677353 beta-lactamase_2500_L188C,beta-lactamase_2500_188,TEM-1,beta-lactamase_2500,P62593,0.677382,NO,188,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.166,-4.777,3.611,,,H,A,0.55,-0.3,17.865,17.865,60.14,PHB,-1.47033,0.361275,0.00295687,0.677382 Ubiquitin_T7E,Ubiquitin_7,Uba1,Ubiquitin,P0CG48,0.677419,NO,7,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.415,-3.554,2.139,4.954,0.094,E,B,0.43,-0.78,0.805,,21.31,BPH,-1.41033,0.205827,0.000647855,0.677419 kka2_1:1_H188L,kka2_1:1_188,Kka2,kka2_1:1,P00552,0.677476,NO,188,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-0.913,-3.61,2.697,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.520039,0.00273139,0.677476 kka2_1:4_R66S,kka2_1:4_66,Kka2,kka2_1:4,P00552,0.677528,NO,66,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-0.922,-3.412,2.49,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.168804,0.00161025,0.677528 beta-lactamase_39_A230H,beta-lactamase_39_230,TEM-1,beta-lactamase_39,P62593,0.67756,NO,230,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.154,-4.737,3.583,,0.01,E,B,0.46,-1.17,1.171,,50,HHA,-1.079,0.0495842,0.00516841,0.67756 kka2_1:2_C31E,kka2_1:2_31,Kka2,kka2_1:2,P00552,0.677603,NO,31,C,E,CE,Special,negativeCharge,5.07,3.22,-1.85,170,121,147,26,108.5,138.4,29.9,-2.246,-1.966,-0.28,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.295029,0.00681582,0.677603 gb1_G240D,gb1_240,gb1,gb1,P06654,0.677778,NO,240,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.921,-3.204,2.283,,,,,,,,,,BOA,-1.87867,0.177985,0.00270792,0.677778 kka2_1:1_A191E,kka2_1:1_191,Kka2,kka2_1:1,P00552,0.677801,NO,191,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.831,-3.502,2.671,,,.,b,0.46,-0.94,0.53,,50,AHO,-0.868667,0.520039,0.00338807,0.677801 kka2_1:2_D90Q,kka2_1:2_90,Kka2,kka2_1:2,P00552,0.677818,NO,90,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.459,-2.781,0.322,,0.104,E,B,0.75,0.73,6.085,,64.39,BAH,-1.72833,0.295029,0.00583842,0.677818 kka2_1:2_R140L,kka2_1:2_140,Kka2,kka2_1:2,P00552,0.677858,NO,140,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.351,-3.517,2.166,,0.12,H,A,1.2,0.2,0.352,,53.03,BBH,-1.885,0.295029,0.00430167,0.677858 kka2_1:2_V97L,kka2_1:2_97,Kka2,kka2_1:2,P00552,0.677893,NO,97,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.453,-1.404,-0.049,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.295029,0.00737869,0.677893 beta-lactamase_625_S122P,beta-lactamase_625_122,TEM-1,beta-lactamase_625,P62593,0.678008,NO,122,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.406,-4.011,1.605,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.213352,0.00497825,0.678008 beta-lactamase_0_T187R,beta-lactamase_0_187,TEM-1,beta-lactamase_0,P62593,0.678057,NO,187,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.401,-3.885,2.484,,0.007,H,A,0.22,-1.19,3.259,,67.48,PPH,-1.69633,0.0500837,0.00491782,0.678057 kka2_1:1_D23H,kka2_1:1_23,Kka2,kka2_1:1,P00552,0.67808,NO,23,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.459,-3.07,0.611,,0.695,E,B,0.75,-0.65,2.655,,65.53,HAH,-1.94033,0.520039,0.007195,0.67808 kka2_1:4_G245D,kka2_1:4_245,Kka2,kka2_1:4,P00552,0.678144,NO,245,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.812,-3.456,2.644,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.168804,0.00683899,0.678144 beta-lactamase_625_G240S,beta-lactamase_625_240,TEM-1,beta-lactamase_625,P62593,0.678202,NO,240,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.537,-2.475,0.938,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.213352,0.00591201,0.678202 PSD95pdz3_L379S,PSD95pdz3_379,PSD95pdz3,PSD95pdz3,P31016,0.678303,NO,379,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.347,-3.292,1.945,5.37777,,,,,16.8762,,,,HHB,-1.35667,0.0758425,0.00029733,0.678303 beta-lactamase_2500_R63P,beta-lactamase_2500_63,TEM-1,beta-lactamase_2500,P62593,0.67835,NO,63,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-0.943,-3.929,2.986,,0.218,,B,1.2,-0.31,0.929,,44.06,ABH,-0.992333,0.361275,0.00126938,0.67835 kka2_1:8_L67S,kka2_1:8_67,Kka2,kka2_1:8,P00552,0.67835,NO,67,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.741,-3.639,2.898,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.100394,0.00102787,0.67835 kka2_1:8_L67S,kka2_1:8_67,Kka2,kka2_1:8,P00552,0.67835,NO,67,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.741,-3.639,2.898,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.100394,0.00102787,0.67835 kka2_1:2_F171M,kka2_1:2_171,Kka2,kka2_1:2,P00552,0.678352,NO,171,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.326,-4.328,3.002,,0.154,H,A,0.58,-0.1,2.645,,63.64,HHH,-1.45433,0.295029,0.00821426,0.678352 beta-lactamase_0_V72W,beta-lactamase_0_72,TEM-1,beta-lactamase_0,P62593,0.67837,NO,72,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.658,-3.279,1.621,,,H,A,0.44,-1.03,2.964,,65.73,BHH,-1.32167,0.0500837,0.00501194,0.67837 beta-lactamase_156_A230F,beta-lactamase_156_230,TEM-1,beta-lactamase_156,P62593,0.678466,NO,230,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.154,-4.217,3.063,,0.01,E,B,0.46,-1.17,2.179,,50,HHA,-1.079,0.111618,0.00516841,0.678466 kka2_1:2_P45M,kka2_1:2_45,Kka2,kka2_1:2,P00552,0.678521,NO,45,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.774,-4.81,3.036,,0.669,,B,0.52,-0.76,4.882,,71.59,BOH,-2.152,0.295029,0.00590481,0.678521 kka2_1:2_A108V,kka2_1:2_108,Kka2,kka2_1:2,P00552,0.678774,NO,108,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.061,-3.068,1.007,,0.243,.,B,0.46,-1.34,2.462,,71.59,HHO,-1.57033,0.295029,0.00751209,0.678774 kka2_1:8_A224G,kka2_1:8_224,Kka2,kka2_1:8,P00552,0.678823,NO,224,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.977,-3.154,2.177,,,H,A,0.46,-1.26,0.357,,63.64,HHP,-1.41033,0.100394,0.00352047,0.678823 kka2_1:8_A224G,kka2_1:8_224,Kka2,kka2_1:8,P00552,0.678823,NO,224,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.977,-3.154,2.177,,,H,A,0.46,-1.26,0.357,,63.64,HHP,-1.41033,0.100394,0.00352047,0.678823 gb1_E282I,gb1_282,gb1,gb1,P06654,0.678966,NO,282,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.318,-3.781,2.463,,,,,,,1.075,,35.71,PAO,-1.573,0.177985,0.00209643,0.678966 gb1_K254C,gb1_254,gb1,gb1,P06654,0.678966,NO,254,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.748,-5.031,3.283,,,,,,,1.793,,37.28,ABH,-2.195,0.177985,0.00622711,0.678966 gb1_Y271V,gb1_271,gb1,gb1,P06654,0.678966,NO,271,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-1.181,-3.081,1.9,,,,,,,,,,PHA,-1.92933,0.177985,0.00236544,0.678966 beta-lactamase_0_S256V,beta-lactamase_0_256,TEM-1,beta-lactamase_0,P62593,0.679122,NO,256,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.0500837,0.00710634,0.679122 beta-lactamase_2500_H94C,beta-lactamase_2500_94,TEM-1,beta-lactamase_2500,P62593,0.679213,NO,94,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-2.5,-5.143,2.643,,0.776,,B,0.17,1.24,1.176,,77.62,HBH,-1.872,0.361275,0.00389226,0.679213 kka2_1:1_G234E,kka2_1:1_234,Kka2,kka2_1:1,P00552,0.679214,NO,234,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-2.9,-1.763,-1.137,,0.494,H,A,0.29,-0.29,1.753,,71.59,OOA,-1.86767,0.520039,0.00984449,0.679214 kka2_1:8_G205S,kka2_1:8_205,Kka2,kka2_1:8,P00552,0.679216,NO,205,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.596,-3.189,2.593,,,E,b,0.75,-1.05,,,,POH,-1.09933,0.100394,0.00221855,0.679216 kka2_1:8_G205S,kka2_1:8_205,Kka2,kka2_1:8,P00552,0.679216,NO,205,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.596,-3.189,2.593,,,E,b,0.75,-1.05,,,,POH,-1.09933,0.100394,0.00221855,0.679216 beta-lactamase_R118P,beta-lactamase_118,TEM-1,beta-lactamase,P62593,0.679251,NO,118,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.413,-3.946,1.533,5.8227,0.457,H,A,0.68,1.39,2.144,,77.62,HBA,-1.785,0.221079,0.00538794,0.679251 beta-lactamase_2500_L137T,beta-lactamase_2500_137,TEM-1,beta-lactamase_2500,P62593,0.679343,NO,137,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.03,-3.486,2.456,,,H,A,0.55,-0.38,0.769,,42.31,HHP,-1.58933,0.361275,0.00278599,0.679343 beta-lactamase_0_E35Q,beta-lactamase_0_35,TEM-1,beta-lactamase_0,P62593,0.679365,NO,35,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-0.869,-3.292,2.423,,0.15,H,A,1.04,0.21,0.664,,46.85,HAA,-1.88667,0.0500837,0.00174441,0.679365 beta-lactamase_2500_D212Q,beta-lactamase_2500_212,TEM-1,beta-lactamase_2500,P62593,0.67937,NO,212,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.624,-3.949,2.325,,0.037,,b,0.75,-0.58,12.482,,74.48,HAB,-1.77667,0.361275,0.00644302,0.67937 kka2_1:4_E182F,kka2_1:4_182,Kka2,kka2_1:4,P00552,0.679432,NO,182,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.516,-4.259,2.743,,0.326,.,B,1.04,0.75,4.755,,65.53,OAA,-1.806,0.168804,0.00641548,0.679432 beta-lactamase_0_T107Q,beta-lactamase_0_107,TEM-1,beta-lactamase_0,P62593,0.679485,NO,107,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.117,-3.889,2.772,,,G,A,0.22,-0.06,3.73,,67.83,HPA,-1.265,0.0500837,0.00239347,0.679485 kka2_1:4_H188Q,kka2_1:4_188,Kka2,kka2_1:4,P00552,0.679523,NO,188,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-0.913,-2.723,1.81,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.168804,0.00273139,0.679523 beta-lactamase_0_I277K,beta-lactamase_0_277,TEM-1,beta-lactamase_0,P62593,0.679548,NO,277,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.0500837,0.0169305,0.679548 beta-lactamase_0_P181Q,beta-lactamase_0_181,TEM-1,beta-lactamase_0,P62593,0.679558,NO,181,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.813,-3.925,3.112,,,H,A,0.52,-1.14,1.357,,61.54,HOH,-1.795,0.0500837,0.000703122,0.679558 beta-lactamase_0_H151I,beta-lactamase_0_151,TEM-1,beta-lactamase_0,P62593,0.679564,NO,151,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-2.96,-4.091,1.131,,0.594,H,A,0.17,0.1,9.375,,77.62,HBP,-2.34767,0.0500837,0.00216946,0.679564 kka2_1:4_R147K,kka2_1:4_147,Kka2,kka2_1:4,P00552,0.679751,NO,147,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.123,-3.064,1.941,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.168804,0.00549168,0.679751 beta-lactamase_0_S57M,beta-lactamase_0_57,TEM-1,beta-lactamase_0,P62593,0.679932,NO,57,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.918,-4.684,2.766,,0.352,E,B,0.27,-0.18,1.454,,72.73,APH,-2.29167,0.0500837,0.00492804,0.679932 gb1_E282L,gb1_282,gb1,gb1,P06654,0.680145,NO,282,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.318,-3.354,2.036,,,,,,,1.075,,35.71,PAO,-1.573,0.177985,0.00209643,0.680145 kka2_1:8_D134T,kka2_1:8_134,Kka2,kka2_1:8,P00552,0.680192,NO,134,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.969,-3.471,2.502,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.100394,0.00270812,0.680192 kka2_1:8_D134T,kka2_1:8_134,Kka2,kka2_1:8,P00552,0.680192,NO,134,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.969,-3.471,2.502,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.100394,0.00270812,0.680192 kka2_1:4_H135D,kka2_1:4_135,Kka2,kka2_1:4,P00552,0.680222,NO,135,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-1.331,-3.636,2.305,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.168804,0.00532566,0.680222 beta-lactamase_D212C,beta-lactamase_212,TEM-1,beta-lactamase,P62593,0.680295,NO,212,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.624,-5.061,3.437,4.9705,0.037,,b,1.3,-0.58,12.482,,74.48,HAB,-1.77667,0.221079,0.00644302,0.680295 kka2_1:2_Y218H,kka2_1:2_218,Kka2,kka2_1:2,P00552,0.68036,NO,218,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-1.438,-1.83,0.392,,0.122,H,A,0.21,-0.69,1.022,,56.06,BHP,-1.17533,0.295029,0.0126098,0.68036 beta-lactamase_2500_P255W,beta-lactamase_2500_255,TEM-1,beta-lactamase_2500,P62593,0.68039,NO,255,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.361275,0.00499612,0.68039 kka2_1:8_A117E,kka2_1:8_117,Kka2,kka2_1:8,P00552,0.680479,NO,117,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.828,-3.532,2.704,,,H,A,1.04,-0.78,0.755,,45.83,HHA,-1.79333,0.100394,0.00282984,0.680479 kka2_1:8_A117E,kka2_1:8_117,Kka2,kka2_1:8,P00552,0.680479,NO,117,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.828,-3.532,2.704,,,H,A,1.04,-0.78,0.755,,45.83,HHA,-1.79333,0.100394,0.00282984,0.680479 kka2_1:8_S105E,kka2_1:8_105,Kka2,kka2_1:8,P00552,0.680523,NO,105,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.945,-2.784,0.839,,0.056,S,B,0.27,-1.04,2.115,,65.53,PPB,-2.17033,0.100394,0.00847233,0.680523 kka2_1:8_S105E,kka2_1:8_105,Kka2,kka2_1:8,P00552,0.680523,NO,105,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.945,-2.784,0.839,,0.056,S,B,0.27,-1.04,2.115,,65.53,PPB,-2.17033,0.100394,0.00847233,0.680523 kka2_1:8_G210R,kka2_1:8_210,Kka2,kka2_1:8,P00552,0.68061,NO,210,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.095,-4.007,2.912,,0.103,T,A,0.75,-0.62,2.687,,50,OOB,-0.966667,0.100394,0.00598378,0.68061 kka2_1:8_G210R,kka2_1:8_210,Kka2,kka2_1:8,P00552,0.68061,NO,210,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.095,-4.007,2.912,,0.103,T,A,0.75,-0.62,2.687,,50,OOB,-0.966667,0.100394,0.00598378,0.68061 beta-lactamase_2500_R189I,beta-lactamase_2500_189,TEM-1,beta-lactamase_2500,P62593,0.680742,NO,189,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.844,-4.147,2.303,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.361275,0.0050699,0.680742 kka2_1:4_M197R,kka2_1:4_197,Kka2,kka2_1:4,P00552,0.680751,NO,197,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.707,-4.083,2.376,,0.121,E,B,0.55,-1.19,0.415,,65.53,HHH,-1.847,0.168804,0.00921295,0.680751 PSD95pdz3_D348I,PSD95pdz3_348,PSD95pdz3,PSD95pdz3,P31016,0.680759,NO,348,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.264,-3.692,2.428,5.02473,,,,,16.8925,,,,HAH,-1.306,0.0758425,0.000731866,0.680759 kka2_1:2_V80F,kka2_1:2_80,Kka2,kka2_1:2,P00552,0.680821,NO,80,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.144,-3.963,2.819,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.295029,0.00488211,0.680821 kka2_1:2_H162Y,kka2_1:2_162,Kka2,kka2_1:2,P00552,0.680867,NO,162,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-2.319,-3.937,1.618,,0.071,G,A,0.17,1.01,3.187,,64.39,ABP,-2.02067,0.295029,0.00616145,0.680867 kka2_1:1_V97G,kka2_1:1_97,Kka2,kka2_1:1,P00552,0.680912,NO,97,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.453,-3.796,2.343,,0.083,,B,1.48,-0.83,13.576,13.576,53.03,AHO,-1.85067,0.520039,0.00737869,0.680912 WW_domain_D201I,WW_domain_201,Yap65,WW_domain,P46937,0.680963,NO,201,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.369,-3.78,2.411,4.90312,,,,,,20.806,20.806,70.04,PAO,-1.456,0.153962,0.00248402,0.680963 beta-lactamase_E56F,beta-lactamase_56,TEM-1,beta-lactamase,P62593,0.680985,NO,56,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.043,-4.191,2.148,5.65281,0.198,E,B,0.52,0.31,2.022,,72.73,HAP,-1.94033,0.221079,0.00238534,0.680985 kka2_1:8_M120K,kka2_1:8_120,Kka2,kka2_1:8,P00552,0.681013,NO,120,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-3.877,-3.733,-0.144,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.100394,0.00265808,0.681013 kka2_1:8_M120K,kka2_1:8_120,Kka2,kka2_1:8,P00552,0.681013,NO,120,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-3.877,-3.733,-0.144,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.100394,0.00265808,0.681013 kka2_1:2_A117S,kka2_1:2_117,Kka2,kka2_1:2,P00552,0.681014,NO,117,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.828,-3.072,2.244,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.295029,0.00282984,0.681014 kka2_1:1_E235D,kka2_1:1_235,Kka2,kka2_1:1,P00552,0.68105,NO,235,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.955,-2.602,0.647,,0.631,H,A,1.52,0.12,8.521,,65.53,OAH,-2.07267,0.520039,0.0102806,0.68105 beta-lactamase_2500_M180P,beta-lactamase_2500_180,TEM-1,beta-lactamase_2500,P62593,0.68106,NO,180,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-2.795,-2.76,-0.035,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.361275,0.00552048,0.68106 beta-lactamase_2500_R162T,beta-lactamase_2500_162,TEM-1,beta-lactamase_2500,P62593,0.681065,NO,162,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.016,-3.471,2.455,,0.124,S,B,1.2,-0.37,6.199,,64.69,ABH,-1.25,0.361275,0.000561334,0.681065 beta-lactamase_625_V78F,beta-lactamase_625_78,TEM-1,beta-lactamase_625,P62593,0.681081,NO,78,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.459,-3.883,2.424,,,H,A,0.44,-0.47,2.045,,63.64,HHH,-1.17833,0.213352,0.00492501,0.681081 beta-lactamase_625_L89N,beta-lactamase_625_89,TEM-1,beta-lactamase_625,P62593,0.681197,NO,89,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.096,-4.11,3.014,,0.168,T,A,0.55,0.63,1.599,,64.34,PHO,-1.75767,0.213352,0.00207068,0.681197 kka2_1:1_Q4S,kka2_1:1_4,Kka2,kka2_1:1,P00552,0.681286,NO,4,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.361,-2.105,-0.256,,,,,,,5.615,,71.59,APA,-1.95533,0.520039,0.00239179,0.681286 beta-lactamase_0_T186W,beta-lactamase_0_186,TEM-1,beta-lactamase_0,P62593,0.681299,NO,186,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.522,-5.446,2.924,,0.396,H,A,0.22,-0.28,16.606,16.606,77.62,HPP,-1.77633,0.0500837,0.00485034,0.681299 gb1_G235I,gb1_235,gb1,gb1,P06654,0.681315,NO,235,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.419,-3.653,2.234,,,,,,,0.476,,11.83,POB,-1.86433,0.177985,0.00297491,0.681315 beta-lactamase_0_S233F,beta-lactamase_0_233,TEM-1,beta-lactamase_0,P62593,0.681514,NO,233,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.886,-4.226,2.34,,0.016,E,B,0.27,-1.01,3.579,,77.62,BPO,-1.17267,0.0500837,0.00311415,0.681514 kka2_1:1_F20M,kka2_1:1_20,Kka2,kka2_1:1,P00552,0.681514,NO,20,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-3.354,-4.754,1.4,,0.935,T,B,0.58,-0.41,1.657,,92.05,HHO,-1.992,0.520039,0.00701744,0.681514 beta-lactamase_Y103Q,beta-lactamase_103,TEM-1,beta-lactamase,P62593,0.681528,NO,103,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-1.33,-2.924,1.594,5.71734,0.613,S,l,2.55,1.21,5.721,,63.29,AHP,-1.48767,0.221079,0.00443048,0.681528 kka2_1:2_R202L,kka2_1:2_202,Kka2,kka2_1:2,P00552,0.681617,NO,202,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.761,-3.611,1.85,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.295029,0.00696498,0.681617 Pab1_L142Y,Pab1_142,Pab1,Pab1,P04147,0.68167,NO,142,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.039,-3.755,2.716,,0.007,H,A,0.84,-0.65,,,,HHH,-1.487,0.175299,0.000335477,0.68167 beta-lactamase_Y95P,beta-lactamase_95,TEM-1,beta-lactamase,P62593,0.681683,NO,95,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-1.715,-4.285,2.57,5.67068,0.122,,b,0.96,-0.37,2.341,,77.62,BHP,-2.16167,0.221079,0.00479449,0.681683 kka2_1:1_T28S,kka2_1:1_28,Kka2,kka2_1:1,P00552,0.681735,NO,28,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.883,-2.337,0.454,,0.353,S,B,0.22,2.02,1.12,,63.64,PPH,-1.74467,0.520039,0.00743084,0.681735 kka2_1:1_L53Y,kka2_1:1_53,Kka2,kka2_1:1,P00552,0.681744,NO,53,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-2.681,-4.449,1.768,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.520039,0.00671168,0.681744 kka2_1:1_S68N,kka2_1:1_68,Kka2,kka2_1:1,P00552,0.681766,NO,68,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.623,-3.062,0.439,,0.48,H,A,0.27,-0.1,2.655,,71.59,HPH,-1.40767,0.520039,0.00608265,0.681766 kka2_1:8_T225E,kka2_1:8_225,Kka2,kka2_1:8,P00552,0.681781,NO,225,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.393,-3.79,1.397,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.100394,0.0113598,0.681781 kka2_1:8_T225E,kka2_1:8_225,Kka2,kka2_1:8,P00552,0.681781,NO,225,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.393,-3.79,1.397,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.100394,0.0113598,0.681781 kka2_1:4_C31S,kka2_1:4_31,Kka2,kka2_1:4,P00552,0.681814,NO,31,C,S,CS,Special,Polar,5.07,5.68,0.61,112,121,105,-16,108.5,89,-19.5,-2.246,-3.485,1.239,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.168804,0.00681582,0.681814 kka2_1:1_R173Q,kka2_1:1_173,Kka2,kka2_1:1,P00552,0.681943,NO,173,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.407,-2.729,0.322,,0.308,H,A,0.16,-0.13,14.756,14.756,65.53,HBH,-1.70533,0.520039,0.00784999,0.681943 beta-lactamase_I54G,beta-lactamase_54,TEM-1,beta-lactamase,P62593,0.681977,NO,54,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-2.838,-3.612,0.774,5.40541,0.669,E,B,0.77,-0.14,3.946,,73.78,BHH,-2.337,0.221079,0.00403589,0.681977 kka2_1:8_D62Q,kka2_1:8_62,Kka2,kka2_1:8,P00552,0.681997,NO,62,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.591,-2.887,1.296,,0.262,H,A,0.29,0.08,5.58,,64.39,PAA,-1.77833,0.100394,0.00744243,0.681997 kka2_1:8_D62Q,kka2_1:8_62,Kka2,kka2_1:8,P00552,0.681997,NO,62,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.591,-2.887,1.296,,0.262,H,A,0.29,0.08,5.58,,64.39,PAA,-1.77833,0.100394,0.00744243,0.681997 beta-lactamase_625_P224C,beta-lactamase_625_224,TEM-1,beta-lactamase_625,P62593,0.682081,NO,224,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.893,-5.08,4.187,,0.383,,B,0.52,-0.3,1.35,,74.48,HOH,-1.26433,0.213352,0.00189564,0.682081 beta-lactamase_0_A282I,beta-lactamase_0_282,TEM-1,beta-lactamase_0,P62593,0.682121,NO,282,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.0500837,0.0449821,0.682121 kka2_1:1_D190L,kka2_1:1_190,Kka2,kka2_1:1,P00552,0.682165,NO,190,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.708,-3.836,3.128,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.520039,0.00247989,0.682165 beta-lactamase_G236D,beta-lactamase_236,TEM-1,beta-lactamase,P62593,0.682169,NO,236,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.784,-3.513,2.729,4.7915,0.241,,b,0.23,-0.59,1.883,,64.69,HOA,-1.36933,0.221079,0.00162372,0.682169 beta-lactamase_G263F,beta-lactamase_263,TEM-1,beta-lactamase,P62593,0.682207,NO,263,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-2.031,-4.425,2.394,5.09799,0.517,S,l,0.77,0.31,16.425,16.425,77.62,POP,-1.78267,0.221079,0.0110582,0.682207 kka2_1:1_H124D,kka2_1:1_124,Kka2,kka2_1:1,P00552,0.682214,NO,124,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-0.84,-3.497,2.657,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.520039,0.00211296,0.682214 beta-lactamase_2500_I245A,beta-lactamase_2500_245,TEM-1,beta-lactamase_2500,P62593,0.682256,NO,245,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.068,-3.611,2.543,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.361275,0.00391032,0.682256 kka2_1:2_D127Y,kka2_1:2_127,Kka2,kka2_1:2,P00552,0.682301,NO,127,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.364,-4.502,3.138,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.295029,0.00660501,0.682301 kka2_1:1_G245L,kka2_1:1_245,Kka2,kka2_1:1,P00552,0.682363,NO,245,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.812,-3.785,2.973,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.520039,0.00683899,0.682363 kka2_1:1_R258L,kka2_1:1_258,Kka2,kka2_1:1,P00552,0.682435,NO,258,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.626,-2.791,1.165,,0.316,H,A,1.2,-0.85,7.485,7.485,53.03,HBH,-1.25933,0.520039,0.00983174,0.682435 beta-lactamase_E87H,beta-lactamase_87,TEM-1,beta-lactamase,P62593,0.682472,NO,87,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.421,-4.575,3.154,5.41929,0.048,,B,0.52,0.92,1.754,,64.69,PAP,-1.969,0.221079,0.00337888,0.682472 gb1_K254F,gb1_254,gb1,gb1,P06654,0.682477,NO,254,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.748,-4.158,2.41,,,,,,,1.793,,37.28,ABH,-2.195,0.177985,0.00622711,0.682477 kka2_1:1_C192F,kka2_1:1_192,Kka2,kka2_1:1,P00552,0.682499,NO,192,C,F,CF,Special,Hydrophobic,5.07,3.32051,-1.74949,205,121,165,44,108.5,189.9,81.4,-1.067,-4.014,2.947,,0.095,.,B,0.46,-0.75,2.749,,50,HOH,-0.960333,0.520039,0.00485428,0.682499 beta-lactamase_0_R59H,beta-lactamase_0_59,TEM-1,beta-lactamase_0,P62593,0.682573,NO,59,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.345,-4.424,3.079,,0.329,S,L,1.2,-0.09,2.919,,73.08,HBO,-2.24267,0.0500837,0.00318082,0.682573 E1_Ubiquitin_G76A,E1_Ubiquitin_76,Uba1,E1_Ubiquitin,P0CG63,0.682582,NO,76,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.999,-2.851,1.852,,0.23,,B,0.75,0.08,1.702,,83.73,OOO,-0.999,0.18783,0.00125575,0.682582 beta-lactamase_0_Q97Y,beta-lactamase_0_97,TEM-1,beta-lactamase_0,P62593,0.682633,NO,97,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.072,-4.35,2.278,,0.823,G,A,0.64,2.42,16.954,16.954,77.62,PPP,-2.43833,0.0500837,0.0045116,0.682633 kka2_1:4_W91S,kka2_1:4_91,Kka2,kka2_1:4,P00552,0.682649,NO,91,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-1.178,-3.808,2.63,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.168804,0.00358653,0.682649 beta-lactamase_A15E,beta-lactamase_15,TEM-1,beta-lactamase,P62593,0.682669,NO,15,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.654,-3.477,1.823,,,,,,,31.998,31.998,93.01,HHH,-2.10833,0.221079,0.00248966,0.682669 beta-lactamase_0_E35G,beta-lactamase_0_35,TEM-1,beta-lactamase_0,P62593,0.682762,NO,35,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-0.869,-3.356,2.487,,0.15,H,A,1.04,0.21,0.664,,46.85,HAA,-1.88667,0.0500837,0.00174441,0.682762 beta-lactamase_156_M184H,beta-lactamase_156_184,TEM-1,beta-lactamase_156,P62593,0.682771,NO,184,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.593,-4.818,3.225,,,H,A,0.55,-0.87,1.671,,62.94,HHH,-1.41,0.111618,0.00356019,0.682771 kka2_1:1_L241M,kka2_1:1_241,Kka2,kka2_1:1,P00552,0.682773,NO,241,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.158,-4.084,2.926,,0.08,H,A,0.55,-0.82,1.685,,63.26,HHH,-1.58533,0.520039,0.0117299,0.682773 kka2_1:1_R89C,kka2_1:1_89,Kka2,kka2_1:1,P00552,0.682801,NO,89,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.548,-5.235,3.687,,0.209,E,B,0.16,1.41,14.396,14.396,64.39,OBA,-1.89867,0.520039,0.00524373,0.682801 beta-lactamase_0_A124D,beta-lactamase_0_124,TEM-1,beta-lactamase_0,P62593,0.682838,NO,124,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.181,-3.709,2.528,,,H,A,0.46,-0.9,1.876,,64.34,HHH,-1.152,0.0500837,0.00481399,0.682838 beta-lactamase_D212K,beta-lactamase_212,TEM-1,beta-lactamase,P62593,0.682872,NO,212,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.624,-3.581,1.957,4.9705,0.037,,b,1.3,-0.58,12.482,,74.48,HAB,-1.77667,0.221079,0.00644302,0.682872 kka2_1:1_M178Y,kka2_1:1_178,Kka2,kka2_1:1,P00552,0.682879,NO,178,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-3.206,-4.367,1.161,,0.554,.,b,0.55,0.68,3.152,,71.59,BHO,-2.154,0.520039,0.00717253,0.682879 beta-lactamase_0_R91D,beta-lactamase_0_91,TEM-1,beta-lactamase_0,P62593,0.6831,NO,91,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.392,-3.521,2.129,,0.444,,B,1.2,0.96,4.557,,50.35,OBB,-1.73367,0.0500837,0.00380226,0.6831 kka2_1:2_D156R,kka2_1:2_156,Kka2,kka2_1:2,P00552,0.683164,NO,156,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.696,-3.967,2.271,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.295029,0.00926998,0.683164 kka2_1:2_L93V,kka2_1:2_93,Kka2,kka2_1:2,P00552,0.683183,NO,93,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.815,-2.967,2.152,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.295029,0.00131498,0.683183 beta-lactamase_0_P181V,beta-lactamase_0_181,TEM-1,beta-lactamase_0,P62593,0.683218,NO,181,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.813,-3.492,2.679,,,H,A,0.52,-1.14,1.357,,61.54,HOH,-1.795,0.0500837,0.000703122,0.683218 kka2_1:2_R38L,kka2_1:2_38,Kka2,kka2_1:2,P00552,0.683253,NO,38,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.207,-1.87,0.663,,0.355,E,B,1.2,-1.13,6.872,6.872,52.27,HBH,-1.28567,0.295029,0.00372499,0.683253 beta-lactamase_2500_G216E,beta-lactamase_2500_216,TEM-1,beta-lactamase_2500,P62593,0.683308,NO,216,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.477,-2.451,0.974,,0.437,I,A,0.29,-0.58,1.983,,74.48,HOO,-1.68067,0.361275,0.00639568,0.683308 beta-lactamase_D212P,beta-lactamase_212,TEM-1,beta-lactamase,P62593,0.683338,NO,212,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.624,-3.916,2.292,4.9705,0.037,,b,1.3,-0.58,12.482,,74.48,HAB,-1.77667,0.221079,0.00644302,0.683338 kka2_1:4_I115T,kka2_1:4_115,Kka2,kka2_1:4,P00552,0.683448,NO,115,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.606,-3.564,1.958,,0.105,H,A,1.52,-1.18,9.996,9.996,65.53,PHH,-2.205,0.168804,0.00836567,0.683448 kka2_1:8_L259G,kka2_1:8_259,Kka2,kka2_1:8,P00552,0.683466,NO,259,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.088,-3.711,2.623,,0.036,H,A,1.59,-0.15,1.83,,48.48,BHH,-1.15167,0.100394,0.0206964,0.683466 kka2_1:8_L259G,kka2_1:8_259,Kka2,kka2_1:8,P00552,0.683466,NO,259,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.088,-3.711,2.623,,0.036,H,A,1.59,-0.15,1.83,,48.48,BHH,-1.15167,0.100394,0.0206964,0.683466 kka2_1:4_G55P,kka2_1:4_55,Kka2,kka2_1:4,P00552,0.6835,NO,55,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.625,-4.068,2.443,,0.517,S,b,0.75,1.19,15.753,15.753,63.64,POH,-2.05967,0.168804,0.00667877,0.6835 beta-lactamase_0_A183Y,beta-lactamase_0_183,TEM-1,beta-lactamase_0,P62593,0.683501,NO,183,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.231,-4.261,3.03,,0.155,H,A,0.46,-0.91,1.48,,77.62,HHH,-1.53367,0.0500837,0.00296631,0.683501 kka2_1:2_T51N,kka2_1:2_51,Kka2,kka2_1:2,P00552,0.683522,NO,51,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.199,-3.862,1.663,,0.05,E,B,0.22,-0.05,13.165,13.165,63.64,BPA,-1.76767,0.295029,0.00628861,0.683522 beta-lactamase_39_I277S,beta-lactamase_39_277,TEM-1,beta-lactamase_39,P62593,0.683532,NO,277,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.0495842,0.0169305,0.683532 beta-lactamase_0_K213N,beta-lactamase_0_213,TEM-1,beta-lactamase_0,P62593,0.68357,NO,213,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.81,-3.623,1.813,,0.67,,A,2.34,0.29,3.015,,67.83,ABH,-1.57767,0.0500837,0.00610411,0.68357 beta-lactamase_G142Q,beta-lactamase_142,TEM-1,beta-lactamase,P62593,0.683616,NO,142,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.707,-4.087,3.38,4.55474,0.034,,p,0.77,-0.64,1.947,,64.69,OOO,-0.834,0.221079,0.00060149,0.683616 beta-lactamase_V257F,beta-lactamase_257,TEM-1,beta-lactamase,P62593,0.683616,NO,257,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.533,-3.944,2.411,5.31999,,E,B,0.96,-0.7,1.463,,58.74,HHH,-1.70967,0.221079,0.00756629,0.683616 gb1_G240L,gb1_240,gb1,gb1,P06654,0.68363,NO,240,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.921,-3.544,2.623,,,,,,,,,,BOA,-1.87867,0.177985,0.00270792,0.68363 gb1_V280H,gb1_280,gb1,gb1,P06654,0.68363,NO,280,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.764,-4.68,2.916,,,,,,,0.874,,35.71,PHP,-1.63733,0.177985,0.00321577,0.68363 beta-lactamase_2500_D212G,beta-lactamase_2500_212,TEM-1,beta-lactamase_2500,P62593,0.683734,NO,212,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.624,-2.198,0.574,,0.037,,b,0.75,-0.58,12.482,,74.48,HAB,-1.77667,0.361275,0.00644302,0.683734 kka2_1:4_G99V,kka2_1:4_99,Kka2,kka2_1:4,P00552,0.683823,NO,99,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.596,-3.782,3.186,,0.368,S,g,0.29,-0.87,,,,OOP,-1.63067,0.168804,0.00186055,0.683823 kka2_1:4_L107C,kka2_1:4_107,Kka2,kka2_1:4,P00552,0.683823,NO,107,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.238,-4.827,3.589,,0.197,.,B,0.55,-1.1,0.398,,71.59,BHH,-2.143,0.168804,0.00561937,0.683823 kka2_1:1_K112Q,kka2_1:1_112,Kka2,kka2_1:1,P00552,0.683974,NO,112,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-2.491,-2.826,0.335,,0.076,H,A,2.34,-1.37,23.433,23.433,56.06,ABH,-2.00133,0.520039,0.00645389,0.683974 kka2_1:2_G151L,kka2_1:2_151,Kka2,kka2_1:2,P00552,0.684058,NO,151,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.873,-3.818,2.945,,0.678,T,l,0.29,1.36,1.357,,49.62,HOH,-1.11433,0.295029,0.00339918,0.684058 WW_domain_T196H,WW_domain_196,Yap65,WW_domain,P46937,0.684147,NO,196,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.782,-4.489,2.707,5.5744,,,,,,5.836,,70.04,PPP,-1.732,0.153962,0.00421377,0.684147 kka2_1:8_L107N,kka2_1:8_107,Kka2,kka2_1:8,P00552,0.684154,NO,107,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.238,-4.107,2.869,,0.197,.,B,0.55,-1.1,4.478,,71.59,BHH,-2.143,0.100394,0.00561937,0.684154 kka2_1:8_L107N,kka2_1:8_107,Kka2,kka2_1:8,P00552,0.684154,NO,107,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.238,-4.107,2.869,,0.197,.,B,0.55,-1.1,4.478,,71.59,BHH,-2.143,0.100394,0.00561937,0.684154 kka2_1:4_V36M,kka2_1:4_36,Kka2,kka2_1:4,P00552,0.68416,NO,36,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-0.898,-4.103,3.205,,0.292,E,B,0.44,0.21,0.278,,52.27,HHH,-1.484,0.168804,0.00245633,0.68416 kka2_1:2_A71Y,kka2_1:2_71,Kka2,kka2_1:2,P00552,0.684176,NO,71,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.824,-4.36,2.536,,0.553,H,A,0.46,0.08,9.788,,64.39,HHP,-1.74033,0.295029,0.00727707,0.684176 beta-lactamase_0_Q276E,beta-lactamase_0_276,TEM-1,beta-lactamase_0,P62593,0.684232,NO,276,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.0500837,0.0191712,0.684232 beta-lactamase_0_D161L,beta-lactamase_0_161,TEM-1,beta-lactamase_0,P62593,0.684376,NO,161,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.891,-3.777,2.886,,0.341,,A,0.75,-0.52,0.795,,61.19,HAB,-0.961333,0.0500837,0.000897697,0.684376 beta-lactamase_0_R81W,beta-lactamase_0_81,TEM-1,beta-lactamase_0,P62593,0.684384,NO,81,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.466,-5.415,3.949,,0.218,H,A,1.2,1.66,0.332,,50,PBH,-1.60667,0.0500837,0.00499763,0.684384 kka2_1:8_D127I,kka2_1:8_127,Kka2,kka2_1:8,P00552,0.684437,NO,127,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.364,-4.127,2.763,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.100394,0.00660501,0.684437 kka2_1:8_D127I,kka2_1:8_127,Kka2,kka2_1:8,P00552,0.684437,NO,127,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.364,-4.127,2.763,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.100394,0.00660501,0.684437 kka2_1:8_M197D,kka2_1:8_197,Kka2,kka2_1:8,P00552,0.684515,NO,197,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.707,-4.104,2.397,,0.121,E,B,1.59,-1.19,4.408,,65.53,HHH,-1.847,0.100394,0.00921295,0.684515 kka2_1:8_M197D,kka2_1:8_197,Kka2,kka2_1:8,P00552,0.684515,NO,197,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.707,-4.104,2.397,,0.121,E,B,1.59,-1.19,4.408,,65.53,HHH,-1.847,0.100394,0.00921295,0.684515 kka2_1:8_F133S,kka2_1:8_133,Kka2,kka2_1:8,P00552,0.684632,NO,133,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-0.871,-3.662,2.791,,0.178,,B,1.62,0.43,1.816,,42.42,OHA,-0.871667,0.100394,0.00182168,0.684632 kka2_1:8_F133S,kka2_1:8_133,Kka2,kka2_1:8,P00552,0.684632,NO,133,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-0.871,-3.662,2.791,,0.178,,B,1.62,0.43,1.816,,42.42,OHA,-0.871667,0.100394,0.00182168,0.684632 beta-lactamase_2500_L89F,beta-lactamase_2500_89,TEM-1,beta-lactamase_2500,P62593,0.684634,NO,89,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.096,-3.844,2.748,,0.168,T,A,0.55,0.63,2.066,,64.34,PHO,-1.75767,0.361275,0.00207068,0.684634 kka2_1:4_H106W,kka2_1:4_106,Kka2,kka2_1:4,P00552,0.684693,NO,106,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-3.13,-3.81,0.68,,1.065,.,a,0.17,-0.95,16.74,16.74,71.59,PBH,-2.10433,0.168804,0.00730778,0.684693 kka2_1:1_M116I,kka2_1:1_116,Kka2,kka2_1:1,P00552,0.684763,NO,116,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-2.482,-2.646,0.164,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.520039,0.00745147,0.684763 kka2_1:1_P179L,kka2_1:1_179,Kka2,kka2_1:1,P00552,0.68489,NO,179,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.974,-2.273,1.299,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.520039,0.00298346,0.68489 beta-lactamase_0_M115Y,beta-lactamase_0_115,TEM-1,beta-lactamase_0,P62593,0.684914,NO,115,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.389,-3.961,2.572,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.0500837,0.0034337,0.684914 kka2_1:2_S105L,kka2_1:2_105,Kka2,kka2_1:2,P00552,0.684939,NO,105,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.945,-2.961,1.016,,0.056,S,B,0.27,-1.04,3.442,,65.53,PPB,-2.17033,0.295029,0.00847233,0.684939 kka2_1:4_G99D,kka2_1:4_99,Kka2,kka2_1:4,P00552,0.684942,NO,99,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.596,-3.497,2.901,,0.368,S,g,0.29,-0.87,,,,OOP,-1.63067,0.168804,0.00186055,0.684942 beta-lactamase_G114W,beta-lactamase_114,TEM-1,beta-lactamase,P62593,0.684983,NO,114,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.094,-5.288,4.194,4.92659,0.011,,p,0.77,0.35,2.148,,41.61,AOH,-1.43733,0.221079,0.00224919,0.684983 beta-lactamase_N130Q,beta-lactamase_130,TEM-1,beta-lactamase,P62593,0.684983,NO,130,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-0.798,-3.674,2.876,5.26686,0.069,H,A,1.08,-0.74,,,,APP,-0.980667,0.221079,0.000683376,0.684983 beta-lactamase_Y103L,beta-lactamase_103,TEM-1,beta-lactamase,P62593,0.684983,NO,103,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-1.33,-3.402,2.072,5.71734,0.613,S,l,2.55,1.21,5.721,,63.29,AHP,-1.48767,0.221079,0.00443048,0.684983 PSD95pdz3_I341R,PSD95pdz3_341,PSD95pdz3,PSD95pdz3,P31016,0.685083,NO,341,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.63,-3.84,2.21,5.73946,,,,,10.3187,,,,HHH,-1.50033,0.0758425,0.000824087,0.685083 kka2_1:1_A35V,kka2_1:1_35,Kka2,kka2_1:1,P00552,0.685088,NO,35,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.127,-3.696,1.569,,0.107,E,B,0.46,1.05,8.405,8.405,71.59,HHH,-1.31767,0.520039,0.00630016,0.685088 kka2_1:1_Q136H,kka2_1:1_136,Kka2,kka2_1:1,P00552,0.685161,NO,136,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-3.021,-3.255,0.234,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.520039,0.00624149,0.685161 beta-lactamase_2500_L192C,beta-lactamase_2500_192,TEM-1,beta-lactamase_2500,P62593,0.685169,NO,192,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.254,-4.743,3.489,,0.095,H,A,0.55,0.35,1.902,,60.14,HHP,-1.41833,0.361275,0.00558728,0.685169 kka2_1:8_C192R,kka2_1:8_192,Kka2,kka2_1:8,P00552,0.685184,NO,192,C,R,CR,Special,PositiveCharge,5.07,6.34148,1.27148,180,121,174,53,108.5,173.4,64.9,-1.067,-4.134,3.067,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.100394,0.00485428,0.685184 kka2_1:8_C192R,kka2_1:8_192,Kka2,kka2_1:8,P00552,0.685184,NO,192,C,R,CR,Special,PositiveCharge,5.07,6.34148,1.27148,180,121,174,53,108.5,173.4,64.9,-1.067,-4.134,3.067,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.100394,0.00485428,0.685184 beta-lactamase_0_I125F,beta-lactamase_0_125,TEM-1,beta-lactamase_0,P62593,0.685186,NO,125,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.441,-3.841,2.4,,,H,A,0.48,-0.7,1.874,,63.29,HHP,-1.248,0.0500837,0.00383964,0.685186 beta-lactamase_Y103I,beta-lactamase_103,TEM-1,beta-lactamase,P62593,0.68519,NO,103,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-1.33,-3.874,2.544,5.71734,0.613,S,l,2.55,1.21,5.721,,63.29,AHP,-1.48767,0.221079,0.00443048,0.68519 beta-lactamase_39_G281R,beta-lactamase_39_281,TEM-1,beta-lactamase_39,P62593,0.685236,NO,281,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.0495842,0.0406482,0.685236 beta-lactamase_E119C,beta-lactamase_119,TEM-1,beta-lactamase,P62593,0.685261,NO,119,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.412,-5.165,3.753,5.33349,0.358,H,A,1.52,0.51,1.983,,63.99,BAH,-1.623,0.221079,0.00386966,0.685261 kka2_1:2_L39I,kka2_1:2_39,Kka2,kka2_1:2,P00552,0.685321,NO,39,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.223,-2.15,0.927,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.295029,0.00493618,0.685321 kka2_1:8_R217C,kka2_1:8_217,Kka2,kka2_1:8,P00552,0.685356,NO,217,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.158,-5.113,3.955,,0.252,T,A,0.16,-0.59,1.151,,52.27,ABH,-1.127,0.100394,0.0047191,0.685356 kka2_1:8_R217C,kka2_1:8_217,Kka2,kka2_1:8,P00552,0.685356,NO,217,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.158,-5.113,3.955,,0.252,T,A,0.16,-0.59,1.151,,52.27,ABH,-1.127,0.100394,0.0047191,0.685356 kka2_1:1_A41Q,kka2_1:1_41,Kka2,kka2_1:1,P00552,0.685367,NO,41,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.879,-2.908,1.029,,0.184,.,B,0.46,-0.96,18.207,18.207,64.39,PHP,-2.477,0.520039,0.00543332,0.685367 beta-lactamase_156_A235H,beta-lactamase_156_235,TEM-1,beta-lactamase_156,P62593,0.685372,NO,235,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.266,-4.769,3.503,,0.32,E,B,0.46,-0.86,1.344,,50,OHO,-0.89,0.111618,0.00493474,0.685372 kka2_1:4_D183T,kka2_1:4_183,Kka2,kka2_1:4,P00552,0.685373,NO,183,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.204,-3.525,2.321,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.168804,0.00426304,0.685373 kka2_1:1_I29V,kka2_1:1_29,Kka2,kka2_1:1,P00552,0.685392,NO,29,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.692,-2.359,0.667,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.520039,0.00619521,0.685392 Ubiquitin_E51K,Ubiquitin_51,Uba1,Ubiquitin,P0CG48,0.685484,NO,51,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.534,-2.642,1.108,5.36711,0.545,,B,,0.72,,,,HAA,-1.357,0.205827,0.000868134,0.685484 Ubiquitin_F4C,Ubiquitin_4,Uba1,Ubiquitin,P0CG48,0.685484,NO,4,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.534,-4.866,3.332,4.77459,0.059,E,B,,-0.46,,,,HHH,-1.504,0.205827,0.000805043,0.685484 Ubiquitin_G10Q,Ubiquitin_10,Uba1,Ubiquitin,P0CG48,0.685484,NO,10,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.396,-3.897,2.501,5.29806,0.115,S,l,,0.2,,,,POB,-1.38633,0.205827,0.000748953,0.685484 Ubiquitin_L15S,Ubiquitin_15,Uba1,Ubiquitin,P0CG48,0.685484,NO,15,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.082,-3.636,2.554,5.14718,0.029,E,B,1.16,-0.53,0.936,,38.69,PHA,-1.40833,0.205827,0.000519738,0.685484 Ubiquitin_L50T,Ubiquitin_50,Uba1,Ubiquitin,P0CG48,0.685484,NO,50,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.107,-3.385,2.278,5.19399,0.029,,B,,-0.92,,,,PHA,-1.52733,0.205827,0.000734242,0.685484 Ubiquitin_T14R,Ubiquitin_14,Uba1,Ubiquitin,P0CG48,0.685484,NO,14,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.598,-2.895,1.297,5.10811,0.345,E,B,,-0.37,,,,HPH,-1.41133,0.205827,0.000632754,0.685484 Ubiquitin_T66P,Ubiquitin_66,Uba1,Ubiquitin,P0CG48,0.685484,NO,66,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.58,-3.97,2.39,5.02702,0.46,E,B,0.8,-0.81,28.36,28.36,39.71,PPH,-1.51667,0.205827,0.000598414,0.685484 Ubiquitin_Y59A,Ubiquitin_59,Uba1,Ubiquitin,P0CG48,0.685484,NO,59,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-1.307,-3.303,1.996,5.05599,0.072,G,A,0.43,-0.74,2.566,,24.53,AHP,-1.568,0.205827,0.000775084,0.685484 beta-lactamase_2500_E46Y,beta-lactamase_2500_46,TEM-1,beta-lactamase_2500,P62593,0.685485,NO,46,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.94,-4.198,2.258,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.361275,0.00427568,0.685485 beta-lactamase_2500_E108P,beta-lactamase_2500_108,TEM-1,beta-lactamase_2500,P62593,0.685498,NO,108,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.46,-3.855,2.395,,0.572,G,A,1.04,1.87,1.147,,72.73,PAB,-1.437,0.361275,0.00413372,0.685498 kka2_1:2_K175S,kka2_1:2_175,Kka2,kka2_1:2,P00552,0.685581,NO,175,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-2.897,-3.083,0.186,,0.579,H,A,1.3,0.51,15.629,15.629,71.59,HBH,-1.82333,0.295029,0.00693093,0.685581 beta-lactamase_625_L192S,beta-lactamase_625_192,TEM-1,beta-lactamase_625,P62593,0.685587,NO,192,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.254,-3.616,2.362,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.213352,0.00558728,0.685587 beta-lactamase_2500_G281C,beta-lactamase_2500_281,TEM-1,beta-lactamase_2500,P62593,0.685588,NO,281,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.361275,0.0406482,0.685588 kka2_1:2_Y22L,kka2_1:2_22,Kka2,kka2_1:2,P00552,0.685629,NO,22,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-1.583,-3.408,1.825,,0.122,.,B,0.21,-0.8,1.838,,65.53,OHA,-1.80333,0.295029,0.00598977,0.685629 beta-lactamase_39_A185Q,beta-lactamase_39_185,TEM-1,beta-lactamase_39,P62593,0.685672,NO,185,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.406,-4.108,2.702,,,H,A,0.46,-1.02,2.68,,65.03,HHP,-1.84033,0.0495842,0.00467449,0.685672 beta-lactamase_156_L218K,beta-lactamase_156_218,TEM-1,beta-lactamase_156,P62593,0.685703,NO,218,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.391,-2.186,0.795,,,I,b,0.55,-0.53,17.202,17.202,74.48,OHH,-1.58867,0.111618,0.00618274,0.685703 kka2_1:1_L81M,kka2_1:1_81,Kka2,kka2_1:1,P00552,0.685802,NO,81,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.427,-2.896,1.469,,0.46,E,A,0.55,-0.14,0.374,,63.64,HHA,-1.50567,0.520039,0.00805839,0.685802 gb1_E282P,gb1_282,gb1,gb1,P06654,0.685913,NO,282,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.318,-3.495,2.177,,,,,,,1.075,,35.71,PAO,-1.573,0.177985,0.00209643,0.685913 gb1_L238N,gb1_238,gb1,gb1,P06654,0.685913,NO,238,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-2.98,-3.524,0.544,,,,,,,0.504,,45.54,PHB,-2.58633,0.177985,0.00205885,0.685913 kka2_1:1_A237E,kka2_1:1_237,Kka2,kka2_1:1,P00552,0.685934,NO,237,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.12,-3.758,1.638,,0.068,H,A,0.46,-0.71,2.369,,92.05,HHA,-2.10433,0.520039,0.012257,0.685934 kka2_1:1_G189V,kka2_1:1_189,Kka2,kka2_1:1,P00552,0.685963,NO,189,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.596,-3.782,3.186,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.520039,0.00253688,0.685963 beta-lactamase_0_I229T,beta-lactamase_0_229,TEM-1,beta-lactamase_0,P62593,0.685996,NO,229,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.267,-2.621,1.354,,0.083,E,B,0.48,-0.76,1.69,,50,HHH,-1.58767,0.0500837,0.00477249,0.685996 beta-lactamase_0_L284E,beta-lactamase_0_284,TEM-1,beta-lactamase_0,P62593,0.685996,NO,284,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.981,,,,0.848,H,A,2.89,0.67,4.544,,77.62,PHH,-1.82133,0.0500837,0.0686156,0.685996 beta-lactamase_0_I125W,beta-lactamase_0_125,TEM-1,beta-lactamase_0,P62593,0.686097,NO,125,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.441,-5.341,3.9,,,H,A,0.48,-0.7,1.874,,63.29,HHP,-1.248,0.0500837,0.00383964,0.686097 kka2_1:2_D82Y,kka2_1:2_82,Kka2,kka2_1:2,P00552,0.686188,NO,82,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.946,-4.406,2.46,,0.341,E,b,0.75,0.52,11.923,11.923,63.64,HAH,-1.98,0.295029,0.00637516,0.686188 beta-lactamase_156_V78N,beta-lactamase_156_78,TEM-1,beta-lactamase_156,P62593,0.686218,NO,78,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.459,-4.189,2.73,,,H,A,0.44,-0.47,1.132,,63.64,HHH,-1.17833,0.111618,0.00492501,0.686218 beta-lactamase_2500_T116M,beta-lactamase_2500_116,TEM-1,beta-lactamase_2500,P62593,0.686241,NO,116,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.28,-4.634,3.354,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.361275,0.00336175,0.686241 kka2_1:1_A129E,kka2_1:1_129,Kka2,kka2_1:1,P00552,0.686247,NO,129,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.656,-2.346,0.69,,0.845,G,A,0.46,0.72,19.686,19.686,92.05,OHP,-1.99,0.520039,0.00726862,0.686247 kka2_1:1_R145L,kka2_1:1_145,Kka2,kka2_1:1,P00552,0.686309,NO,145,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.804,-3.61,1.806,,0.346,H,A,1.2,1.23,23.699,23.699,63.64,HBP,-1.88033,0.520039,0.00846663,0.686309 beta-lactamase_625_D48L,beta-lactamase_625_48,TEM-1,beta-lactamase_625,P62593,0.686315,NO,48,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.101,-3.744,2.643,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.213352,0.0027273,0.686315 beta-lactamase_625_E35D,beta-lactamase_625_35,TEM-1,beta-lactamase_625,P62593,0.686317,NO,35,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-0.869,-2.219,1.35,,0.15,H,A,1.04,0.21,0.664,,46.85,HAA,-1.88667,0.213352,0.00174441,0.686317 kka2_1:4_L259P,kka2_1:4_259,Kka2,kka2_1:4,P00552,0.686338,NO,259,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.088,-4.066,2.978,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.168804,0.0206964,0.686338 kka2_1:1_A137R,kka2_1:1_137,Kka2,kka2_1:1,P00552,0.686409,NO,137,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.156,-3.088,0.932,,0.029,H,A,0.46,0.34,1.323,,63.26,PHB,-2.559,0.520039,0.00515054,0.686409 beta-lactamase_D212A,beta-lactamase_212,TEM-1,beta-lactamase,P62593,0.686422,NO,212,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.624,-2.64,1.016,4.9705,0.037,,b,1.3,-0.58,12.482,,74.48,HAB,-1.77667,0.221079,0.00644302,0.686422 kka2_1:1_W236G,kka2_1:1_236,Kka2,kka2_1:1,P00552,0.686435,NO,236,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-1.363,-2.755,1.392,,0.303,H,A,1.51,-0.76,12.263,12.263,48.48,AHH,-1.81267,0.520039,0.0088796,0.686435 kka2_1:8_D216E,kka2_1:8_216,Kka2,kka2_1:8,P00552,0.686468,NO,216,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.785,-2.854,2.069,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.100394,0.00229969,0.686468 kka2_1:8_D216E,kka2_1:8_216,Kka2,kka2_1:8,P00552,0.686468,NO,216,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.785,-2.854,2.069,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.100394,0.00229969,0.686468 beta-lactamase_2500_I244C,beta-lactamase_2500_244,TEM-1,beta-lactamase_2500,P62593,0.68655,NO,244,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.555,-4.712,3.157,,,E,B,0.48,-0.84,1.683,,77.62,OHH,-1.385,0.361275,0.00605379,0.68655 kka2_1:1_F256L,kka2_1:1_256,Kka2,kka2_1:1,P00552,0.686568,NO,256,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.49,-3.235,1.745,,,H,A,1.62,-0.78,2.354,,53.03,HHH,-1.423,0.520039,0.0132841,0.686568 kka2_1:2_G99V,kka2_1:2_99,Kka2,kka2_1:2,P00552,0.686628,NO,99,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.596,-3.782,3.186,,0.368,S,g,0.29,-0.87,,,,OOP,-1.63067,0.295029,0.00186055,0.686628 beta-lactamase_39_I258N,beta-lactamase_39_258,TEM-1,beta-lactamase_39,P62593,0.686681,NO,258,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.0495842,0.007931,0.686681 beta-lactamase_625_P143M,beta-lactamase_625_143,TEM-1,beta-lactamase_625,P62593,0.686689,NO,143,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.967,-4.554,3.587,,0.075,H,A,0.52,-0.37,1.445,,66.78,OOB,-1.354,0.213352,0.00114551,0.686689 kka2_1:4_V97G,kka2_1:4_97,Kka2,kka2_1:4,P00552,0.686902,NO,97,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.453,-3.796,2.343,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.168804,0.00737869,0.686902 kka2_1:4_R140S,kka2_1:4_140,Kka2,kka2_1:4,P00552,0.68692,NO,140,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.351,-2.551,1.2,,0.12,H,A,1.2,0.2,2.561,,53.03,BBH,-1.885,0.168804,0.00430167,0.68692 Pab1_I196P,Pab1_196,Pab1,Pab1,P04147,0.686965,NO,196,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.795,-3.84,2.045,,,,,,,2.013,,80.59,AHH,-1.44667,0.175299,0.0016933,0.686965 kka2_1:4_R89L,kka2_1:4_89,Kka2,kka2_1:4,P00552,0.687028,NO,89,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.548,-3.591,2.043,,0.209,E,B,1.2,1.41,4.412,,64.39,OBA,-1.89867,0.168804,0.00524373,0.687028 beta-lactamase_2500_M115Q,beta-lactamase_2500_115,TEM-1,beta-lactamase_2500,P62593,0.687113,NO,115,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.389,-3.893,2.504,,0.019,E,B,0.55,0.08,3.261,,69.58,OHP,-1.25433,0.361275,0.0034337,0.687113 kka2_1:4_F256S,kka2_1:4_256,Kka2,kka2_1:4,P00552,0.687127,NO,256,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.49,-3.766,2.276,,,H,A,0.58,-0.78,1.653,,53.03,HHH,-1.423,0.168804,0.0132841,0.687127 kka2_1:8_I221Q,kka2_1:8_221,Kka2,kka2_1:8,P00552,0.68715,NO,221,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.739,-4.324,2.585,,,H,A,1.52,-1.15,1.599,,71.59,AHH,-1.08367,0.100394,0.00945908,0.68715 kka2_1:8_I221Q,kka2_1:8_221,Kka2,kka2_1:8,P00552,0.68715,NO,221,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.739,-4.324,2.585,,,H,A,1.52,-1.15,1.599,,71.59,AHH,-1.08367,0.100394,0.00945908,0.68715 kka2_1:1_G10P,kka2_1:1_10,Kka2,kka2_1:1,P00552,0.68717,NO,10,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.921,-2.317,0.396,,,,,,,1.862,,71.59,HOP,-2.10733,0.520039,0.00289233,0.68717 beta-lactamase_0_Y95T,beta-lactamase_0_95,TEM-1,beta-lactamase_0,P62593,0.687231,NO,95,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-1.715,-3.697,1.982,,0.122,,b,0.21,-0.37,2.914,,77.62,BHP,-2.16167,0.0500837,0.00479449,0.687231 kka2_1:2_A117R,kka2_1:2_117,Kka2,kka2_1:2,P00552,0.687383,NO,117,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.828,-3.824,2.996,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.295029,0.00282984,0.687383 kka2_1:4_D261Y,kka2_1:4_261,Kka2,kka2_1:4,P00552,0.687394,NO,261,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.708,-4.416,3.708,,0.146,G,A,0.75,-0.33,,,,HAA,-0.759333,0.168804,0.0224846,0.687394 kka2_1:2_A237S,kka2_1:2_237,Kka2,kka2_1:2,P00552,0.687399,NO,237,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.12,-3.575,1.455,,0.068,H,A,0.46,-0.71,2.369,,92.05,HHA,-2.10433,0.295029,0.012257,0.687399 beta-lactamase_156_E119L,beta-lactamase_156_119,TEM-1,beta-lactamase_156,P62593,0.687459,NO,119,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.412,-3.669,2.257,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.111618,0.00386966,0.687459 beta-lactamase_0_R176V,beta-lactamase_0_176,TEM-1,beta-lactamase_0,P62593,0.687536,NO,176,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-0.863,-3.754,2.891,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.0500837,0.00105554,0.687536 beta-lactamase_625_P105D,beta-lactamase_625_105,TEM-1,beta-lactamase_625,P62593,0.687637,NO,105,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.813,-3.466,2.653,,0.226,T,A,0.52,0.8,1.154,,63.29,POH,-1.01533,0.213352,0.0011981,0.687637 beta-lactamase_0_G216M,beta-lactamase_0_216,TEM-1,beta-lactamase_0,P62593,0.687666,NO,216,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.477,-4.925,3.448,,0.437,I,A,0.29,-0.58,0.834,,74.48,HOO,-1.68067,0.0500837,0.00639568,0.687666 beta-lactamase_2500_S283W,beta-lactamase_2500_283,TEM-1,beta-lactamase_2500,P62593,0.687692,NO,283,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.361275,0.0429138,0.687692 beta-lactamase_2500_E195L,beta-lactamase_2500_195,TEM-1,beta-lactamase_2500,P62593,0.687723,NO,195,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.186,-3.741,1.555,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.361275,0.00496565,0.687723 beta-lactamase_R220Q,beta-lactamase_220,TEM-1,beta-lactamase,P62593,0.687752,NO,220,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-0.942,-3.517,2.575,5.65995,0.295,I,A,0.68,-0.76,2.164,,74.48,HBP,-1.33633,0.221079,0.00232421,0.687752 beta-lactamase_156_A235K,beta-lactamase_156_235,TEM-1,beta-lactamase_156,P62593,0.68777,NO,235,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.266,-3.575,2.309,,0.32,E,B,0.46,-0.86,1.344,,50,OHO,-0.89,0.111618,0.00493474,0.68777 beta-lactamase_P105G,beta-lactamase_105,TEM-1,beta-lactamase,P62593,0.687894,NO,105,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.813,-3.321,2.508,5.08236,0.226,T,A,0.98,0.8,1.154,,63.29,POH,-1.01533,0.221079,0.0011981,0.687894 PSD95pdz3_A376T,PSD95pdz3_376,PSD95pdz3,PSD95pdz3,P31016,0.6879,NO,376,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.307,-2.878,1.571,4.72134,,,,,17.108,,,,HHH,-1.49567,0.0758425,0.000341232,0.6879 beta-lactamase_625_R59S,beta-lactamase_625_59,TEM-1,beta-lactamase_625,P62593,0.688026,NO,59,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.345,-2.706,1.361,,0.329,S,L,1.2,-0.09,2.995,,73.08,HBO,-2.24267,0.213352,0.00318082,0.688026 beta-lactamase_0_I171R,beta-lactamase_0_171,TEM-1,beta-lactamase_0,P62593,0.688057,NO,171,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-2.431,-2.473,0.042,,0.361,,B,0.48,0.53,16.954,16.954,77.62,HHO,-1.55533,0.0500837,0.00623355,0.688057 kka2_1:4_D159H,kka2_1:4_159,Kka2,kka2_1:4,P00552,0.688071,NO,159,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.82,-4.547,3.727,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.168804,0.0030485,0.688071 beta-lactamase_2500_C75G,beta-lactamase_2500_75,TEM-1,beta-lactamase_2500,P62593,0.688283,NO,75,C,G,CG,Special,Special,5.07,3.29388,-1.77612,159,121,75,-46,108.5,60.1,-48.4,-1.245,-2.515,1.27,,,H,A,0.46,-0.87,0.844,,50,HOO,-1.24333,0.361275,0.0034616,0.688283 kka2_1:2_L39M,kka2_1:2_39,Kka2,kka2_1:2,P00552,0.688283,NO,39,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.223,-4.14,2.917,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.295029,0.00493618,0.688283 beta-lactamase_G76F,beta-lactamase_76,TEM-1,beta-lactamase,P62593,0.688315,NO,76,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.189,-4.264,3.075,4.73862,,H,A,2.05,-0.67,3.059,,67.83,OOH,-1.22267,0.221079,0.00476637,0.688315 kka2_1:2_A224V,kka2_1:2_224,Kka2,kka2_1:2,P00552,0.688325,NO,224,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.977,-2.571,1.594,,,H,A,0.46,-1.26,1.646,,63.64,HHP,-1.41033,0.295029,0.00352047,0.688325 beta-lactamase_0_I93C,beta-lactamase_0_93,TEM-1,beta-lactamase_0,P62593,0.688331,NO,93,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.401,-4.797,3.396,,0.128,E,B,0.48,0.44,1.266,,67.83,BHB,-1.873,0.0500837,0.00527066,0.688331 kka2_1:2_P45L,kka2_1:2_45,Kka2,kka2_1:2,P00552,0.688419,NO,45,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.774,-3.048,1.274,,0.669,,B,0.52,-0.76,4.882,,71.59,BOH,-2.152,0.295029,0.00590481,0.688419 beta-lactamase_625_A124I,beta-lactamase_625_124,TEM-1,beta-lactamase_625,P62593,0.688456,NO,124,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.181,-3.529,2.348,,,H,A,0.46,-0.9,2.027,,64.34,HHH,-1.152,0.213352,0.00481399,0.688456 kka2_1:8_G189C,kka2_1:8_189,Kka2,kka2_1:8,P00552,0.688511,NO,189,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.596,-5.115,4.519,,0.034,S,l,0.75,-0.99,,,,BOA,-0.739,0.100394,0.00253688,0.688511 kka2_1:8_G189C,kka2_1:8_189,Kka2,kka2_1:8,P00552,0.688511,NO,189,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.596,-5.115,4.519,,0.034,S,l,0.75,-0.99,,,,BOA,-0.739,0.100394,0.00253688,0.688511 kka2_1:1_A215E,kka2_1:1_215,Kka2,kka2_1:1,P00552,0.688546,NO,215,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.968,-3.495,2.527,,0.039,E,B,0.46,-0.59,0.754,,50.38,HHA,-1.00467,0.520039,0.00529129,0.688546 kka2_1:1_G213V,kka2_1:1_213,Kka2,kka2_1:1,P00552,0.688563,NO,213,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.596,-3.782,3.186,,,E,b,0.29,-0.4,,,,HOH,-0.920333,0.520039,0.00187654,0.688563 kka2_1:2_W69C,kka2_1:2_69,Kka2,kka2_1:2,P00552,0.688565,NO,69,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-0.859,-4.914,4.055,,0.164,H,A,0.47,0.15,5.074,,38.64,PHH,-1.49967,0.295029,0.0012874,0.688565 Pab1_M189P,Pab1_189,Pab1,Pab1,P04147,0.688565,NO,189,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.406,-3.697,2.291,,0.631,E,b,,2.81,,,,OHH,-1.18,0.175299,0.000278756,0.688565 kka2_1:1_G245R,kka2_1:1_245,Kka2,kka2_1:1,P00552,0.688571,NO,245,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.812,-3.916,3.104,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.520039,0.00683899,0.688571 beta-lactamase_0_L136R,beta-lactamase_0_136,TEM-1,beta-lactamase_0,P62593,0.68863,NO,136,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.232,-4.116,2.884,,,H,A,0.55,-0.34,0.648,,48.95,HHH,-1.088,0.0500837,0.00442304,0.68863 kka2_1:1_P98R,kka2_1:1_98,Kka2,kka2_1:1,P00552,0.688713,NO,98,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.526,-2.723,1.197,,0.391,S,B,0.52,-0.65,1.521,,63.26,HOO,-1.19167,0.520039,0.00622754,0.688713 beta-lactamase_S264I,beta-lactamase_264,TEM-1,beta-lactamase,P62593,0.688736,NO,264,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.985,-3.759,1.774,4.67475,0.04,,B,0.25,0.29,34.251,34.251,73.78,OPP,-2.19867,0.221079,0.0119399,0.688736 beta-lactamase_T27K,beta-lactamase_27,TEM-1,beta-lactamase,P62593,0.688916,NO,27,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.905,-3.516,1.611,5.39752,0.007,H,A,0.69,-0.37,0.745,,93.01,APH,-1.97933,0.221079,0.00306559,0.688916 kka2_1:2_P132R,kka2_1:2_132,Kka2,kka2_1:2,P00552,0.688952,NO,132,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.775,-3.959,3.184,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.295029,0.0018489,0.688952 beta-lactamase_0_V259M,beta-lactamase_0_259,TEM-1,beta-lactamase_0,P62593,0.688989,NO,259,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.0500837,0.0070773,0.688989 beta-lactamase_F64V,beta-lactamase_64,TEM-1,beta-lactamase,P62593,0.689015,NO,64,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-0.841,-3.304,2.463,5.70769,0.006,E,B,1.33,-0.95,,,,BHO,-0.892667,0.221079,0.000947691,0.689015 kka2_1:1_A108V,kka2_1:1_108,Kka2,kka2_1:1,P00552,0.689018,NO,108,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.061,-3.068,1.007,,0.243,.,B,0.46,-1.34,3.156,,71.59,HHO,-1.57033,0.520039,0.00751209,0.689018 beta-lactamase_2500_H110E,beta-lactamase_2500_110,TEM-1,beta-lactamase_2500,P62593,0.689132,NO,110,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-1.706,-2.766,1.06,,0.341,G,a,0.17,1.08,31.31,31.31,64.69,BBH,-1.73333,0.361275,0.00441499,0.689132 kka2_1:4_A224M,kka2_1:4_224,Kka2,kka2_1:4,P00552,0.689177,NO,224,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.977,-4.55,3.573,,,H,A,0.46,-1.26,0.93,,63.64,HHP,-1.41033,0.168804,0.00352047,0.689177 kka2_1:2_D227Q,kka2_1:2_227,Kka2,kka2_1:2,P00552,0.689186,NO,227,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.758,-3.747,1.989,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.295029,0.00745029,0.689186 beta-lactamase_0_L150E,beta-lactamase_0_150,TEM-1,beta-lactamase_0,P62593,0.689224,NO,150,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.326,-3.822,2.496,,,H,A,0.55,-0.2,2.128,,62.94,HHB,-1.86167,0.0500837,0.00463171,0.689224 kka2_1:2_Q26D,kka2_1:2_26,Kka2,kka2_1:2,P00552,0.689245,NO,26,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.18,-3.048,0.868,,0.448,E,B,0.4,0.44,5.022,,92.05,HPP,-2.11167,0.295029,0.00708962,0.689245 kka2_1:4_L67P,kka2_1:4_67,Kka2,kka2_1:4,P00552,0.68926,NO,67,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.741,-4.133,3.392,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.168804,0.00102787,0.68926 kka2_1:8_W91S,kka2_1:8_91,Kka2,kka2_1:8,P00552,0.689273,NO,91,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-1.178,-3.808,2.63,,0.077,E,B,1.51,0.27,2.51,,48.48,AHH,-1.51,0.100394,0.00358653,0.689273 kka2_1:8_W91S,kka2_1:8_91,Kka2,kka2_1:8,P00552,0.689273,NO,91,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-1.178,-3.808,2.63,,0.077,E,B,1.51,0.27,2.51,,48.48,AHH,-1.51,0.100394,0.00358653,0.689273 Pab1_K156H,Pab1_156,Pab1,Pab1,P04147,0.68933,NO,156,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.083,-4.272,3.189,,0.406,E,B,1.82,-0.26,,,,PBH,-1.58167,0.175299,0.000316767,0.68933 kka2_1:4_L223P,kka2_1:4_223,Kka2,kka2_1:4,P00552,0.689379,NO,223,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.861,-4.178,3.317,,,H,A,1.59,-1.24,1.268,,50,HHH,-0.854333,0.168804,0.00253574,0.689379 beta-lactamase_A215H,beta-lactamase_215,TEM-1,beta-lactamase,P62593,0.689425,NO,215,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.503,-4.741,3.238,4.82164,,,a,0.75,-0.93,3.583,,74.48,HHO,-1.42633,0.221079,0.00544007,0.689425 beta-lactamase_0_T158M,beta-lactamase_0_158,TEM-1,beta-lactamase_0,P62593,0.689457,NO,158,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.116,-4.575,3.459,,0.036,,B,0.22,-0.85,1.041,,69.58,HPB,-1.269,0.0500837,0.00341825,0.689457 kka2_1:2_T73F,kka2_1:2_73,Kka2,kka2_1:2,P00552,0.689507,NO,73,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.51,-4.242,1.732,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.295029,0.00628605,0.689507 kka2_1:8_D82T,kka2_1:8_82,Kka2,kka2_1:8,P00552,0.689527,NO,82,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.946,-3.007,1.061,,0.341,E,b,0.29,0.52,7.463,,63.64,HAH,-1.98,0.100394,0.00637516,0.689527 kka2_1:8_D82T,kka2_1:8_82,Kka2,kka2_1:8,P00552,0.689527,NO,82,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.946,-3.007,1.061,,0.341,E,b,0.29,0.52,7.463,,63.64,HAH,-1.98,0.100394,0.00637516,0.689527 kka2_1:8_G245L,kka2_1:8_245,Kka2,kka2_1:8,P00552,0.689527,NO,245,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.812,-3.785,2.973,,0.655,T,g,0.75,0.03,1.148,,65.53,HOH,-1.19833,0.100394,0.00683899,0.689527 kka2_1:8_G245L,kka2_1:8_245,Kka2,kka2_1:8,P00552,0.689527,NO,245,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.812,-3.785,2.973,,0.655,T,g,0.75,0.03,1.148,,65.53,HOH,-1.19833,0.100394,0.00683899,0.689527 beta-lactamase_A215E,beta-lactamase_215,TEM-1,beta-lactamase,P62593,0.689554,NO,215,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.503,-3.531,2.028,4.82164,,,a,0.75,-0.93,3.583,,74.48,HHO,-1.42633,0.221079,0.00544007,0.689554 beta-lactamase_39_C121E,beta-lactamase_39_121,TEM-1,beta-lactamase_39,P62593,0.689645,NO,121,C,E,CE,Special,negativeCharge,5.07,3.22,-1.85,170,121,147,26,108.5,138.4,29.9,-0.953,-3.987,3.034,,,H,A,0.46,-0.81,7.644,,63.29,HOP,-1.46767,0.0495842,0.000744322,0.689645 beta-lactamase_156_T187K,beta-lactamase_156_187,TEM-1,beta-lactamase_156,P62593,0.689789,NO,187,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.401,-3.578,2.177,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.111618,0.00491782,0.689789 beta-lactamase_0_A211F,beta-lactamase_0_211,TEM-1,beta-lactamase_0,P62593,0.689812,NO,211,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.896,-4.364,2.468,,0.369,T,A,0.46,-0.69,8.527,8.527,77.62,AHA,-1.94633,0.0500837,0.00648183,0.689812 beta-lactamase_0_I229R,beta-lactamase_0_229,TEM-1,beta-lactamase_0,P62593,0.689863,NO,229,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.267,-4.174,2.907,,0.083,E,B,0.48,-0.76,1.69,,50,HHH,-1.58767,0.0500837,0.00477249,0.689863 kka2_1:8_F264S,kka2_1:8_264,Kka2,kka2_1:8,P00552,0.689908,NO,264,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.02,-3.713,2.693,,0.296,,?,1.62,0.02,1.553,,71.59,HHO,-0.9655,0.100394,,0.689908 kka2_1:8_F264S,kka2_1:8_264,Kka2,kka2_1:8,P00552,0.689908,NO,264,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.02,-3.713,2.693,,0.296,,?,1.62,0.02,1.553,,71.59,HHO,-0.9655,0.100394,,0.689908 kka2_1:2_G74M,kka2_1:2_74,Kka2,kka2_1:2,P00552,0.690034,NO,74,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.18,-4.972,3.792,,0.621,T,l,0.75,0.2,1.446,,64.39,POH,-1.91667,0.295029,0.00587035,0.690034 kka2_1:1_D216Y,kka2_1:1_216,Kka2,kka2_1:1,P00552,0.690041,NO,216,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.785,-4.248,3.463,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.520039,0.00229969,0.690041 beta-lactamase_A16R,beta-lactamase_16,TEM-1,beta-lactamase,P62593,0.69006,NO,16,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,,-3.869,1.934,,,,,,,,,,HHH,,0.221079,0.00245392,0.69006 beta-lactamase_G279M,beta-lactamase_279,TEM-1,beta-lactamase,P62593,0.69006,NO,279,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.038,-4.792,3.754,4.53882,,H,A,0.46,-0.97,3.066,,62.59,HOH,-1.36467,0.221079,0.0192826,0.69006 beta-lactamase_Q274D,beta-lactamase_274,TEM-1,beta-lactamase,P62593,0.69006,NO,274,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.082,-3.722,1.64,5.6671,0.066,H,A,0.11,-0.27,2.354,,64.69,BPH,-1.931,0.221079,0.0110418,0.69006 kka2_1:1_M178R,kka2_1:1_178,Kka2,kka2_1:1,P00552,0.690126,NO,178,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-3.206,-1.763,-1.443,,0.554,.,b,0.55,0.68,3.152,,71.59,BHO,-2.154,0.520039,0.00717253,0.690126 kka2_1:2_F206L,kka2_1:2_206,Kka2,kka2_1:2,P00552,0.690187,NO,206,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.349,-2.335,0.986,,0.006,E,B,0.58,-1.21,0.978,,63.64,OHH,-1.04,0.295029,0.00936868,0.690187 kka2_1:8_G164I,kka2_1:8_164,Kka2,kka2_1:8,P00552,0.69033,NO,164,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.869,-4.238,3.369,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.100394,0.00442091,0.69033 kka2_1:8_G164I,kka2_1:8_164,Kka2,kka2_1:8,P00552,0.69033,NO,164,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.869,-4.238,3.369,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.100394,0.00442091,0.69033 Pab1_I157F,Pab1_157,Pab1,Pab1,P04147,0.690433,NO,157,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.623,-3.624,2.001,,,,,,,1.439,,79.72,BHH,-1.28667,0.175299,0.0018103,0.690433 beta-lactamase_L100R,beta-lactamase_100,TEM-1,beta-lactamase,P62593,0.690471,NO,100,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.218,-4.123,2.905,5.60291,0.343,,B,1.3,0.13,1.173,,63.29,AHH,-1.23467,0.221079,0.00413885,0.690471 beta-lactamase_39_L79W,beta-lactamase_39_79,TEM-1,beta-lactamase_39,P62593,0.690494,NO,79,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.842,-5.095,4.253,,0.007,H,A,0.55,-0.16,0.823,,50.35,HHP,-1.44333,0.0495842,0.000947397,0.690494 kka2_1:4_F37A,kka2_1:4_37,Kka2,kka2_1:4,P00552,0.690499,NO,37,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.427,-2.571,1.144,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.168804,0.00586193,0.690499 WW_domain_G176S,WW_domain_176,Yap65,WW_domain,P46937,0.690741,NO,176,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.235,-3.038,1.803,6.33142,,,,,,2.71,,78.57,HOH,-1.35467,0.153962,0.00288552,0.690741 kka2_1:1_D156Y,kka2_1:1_156,Kka2,kka2_1:1,P00552,0.690771,NO,156,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.696,-4.451,2.755,,0.884,T,A,0.75,1.87,1.044,,65.53,PAA,-1.765,0.520039,0.00926998,0.690771 beta-lactamase_2500_P217Y,beta-lactamase_2500_217,TEM-1,beta-lactamase_2500,P62593,0.690815,NO,217,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-2.062,-4.376,2.314,,0.496,I,A,0.52,-0.33,0.431,,74.48,OOH,-1.64333,0.361275,0.00463211,0.690815 beta-lactamase_0_A183I,beta-lactamase_0_183,TEM-1,beta-lactamase_0,P62593,0.690909,NO,183,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.231,-2.835,1.604,,0.155,H,A,0.46,-0.91,1.48,,77.62,HHH,-1.53367,0.0500837,0.00296631,0.690909 beta-lactamase_F149G,beta-lactamase_149,TEM-1,beta-lactamase,P62593,0.690916,NO,149,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.299,-3.587,2.288,5.54789,0.195,H,A,1.1,0.11,1.863,,63.99,HHH,-1.46067,0.221079,0.00418462,0.690916 kka2_1:8_L93Q,kka2_1:8_93,Kka2,kka2_1:8,P00552,0.69092,NO,93,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.815,-4.083,3.268,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.100394,0.00131498,0.69092 kka2_1:8_L93Q,kka2_1:8_93,Kka2,kka2_1:8,P00552,0.69092,NO,93,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.815,-4.083,3.268,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.100394,0.00131498,0.69092 beta-lactamase_156_T126P,beta-lactamase_156_126,TEM-1,beta-lactamase_156,P62593,0.690931,NO,126,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.122,-3.758,2.636,,0.05,H,A,0.22,-0.05,1.14,,44.41,HPH,-1.60467,0.111618,0.00244552,0.690931 kka2_1:4_P76V,kka2_1:4_76,Kka2,kka2_1:4,P00552,0.690951,NO,76,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.449,-2.929,1.48,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.168804,0.00625685,0.690951 kka2_1:1_F206S,kka2_1:1_206,Kka2,kka2_1:1,P00552,0.691026,NO,206,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.349,-3.736,2.387,,0.006,E,B,0.58,-1.21,0.978,,63.64,OHH,-1.04,0.520039,0.00936868,0.691026 kka2_1:2_R217L,kka2_1:2_217,Kka2,kka2_1:2,P00552,0.691131,NO,217,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.158,-2.651,1.493,,0.252,T,A,1.2,-0.59,0.381,,52.27,ABH,-1.127,0.295029,0.0047191,0.691131 beta-lactamase_F58G,beta-lactamase_58,TEM-1,beta-lactamase,P62593,0.691134,NO,58,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-2.914,-3.566,0.652,5.55634,0.266,E,B,1.33,-0.07,2.467,,77.62,PHB,-2.059,0.221079,0.00523369,0.691134 kka2_1:8_D208G,kka2_1:8_208,Kka2,kka2_1:8,P00552,0.691173,NO,208,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.708,-3.161,2.453,,0.36,,l,0.29,-1.01,,,,HAO,-0.929667,0.100394,0.00212588,0.691173 kka2_1:8_D208G,kka2_1:8_208,Kka2,kka2_1:8,P00552,0.691173,NO,208,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.708,-3.161,2.453,,0.36,,l,0.29,-1.01,,,,HAO,-0.929667,0.100394,0.00212588,0.691173 kka2_1:4_L243F,kka2_1:4_243,Kka2,kka2_1:4,P00552,0.691202,NO,243,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-2.651,-4.372,1.721,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.168804,0.00884927,0.691202 beta-lactamase_625_G141Y,beta-lactamase_625_141,TEM-1,beta-lactamase_625,P62593,0.691239,NO,141,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.828,-4.424,3.596,,0.575,T,l,0.29,-0.28,0.198,,64.69,HOO,-1.08933,0.213352,0.0012419,0.691239 kka2_1:2_G88V,kka2_1:2_88,Kka2,kka2_1:2,P00552,0.691301,NO,88,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.689,-2.928,1.239,,0.54,S,l,0.75,1.51,2.814,,65.53,HOB,-1.718,0.295029,0.00685559,0.691301 kka2_1:4_Q219K,kka2_1:4_219,Kka2,kka2_1:4,P00552,0.691348,NO,219,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-0.93,-3.033,2.103,,0.088,H,A,0.64,-0.85,1.537,,50,HPA,-1.05167,0.168804,0.00237913,0.691348 kka2_1:2_I115T,kka2_1:2_115,Kka2,kka2_1:2,P00552,0.691354,NO,115,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.606,-3.564,1.958,,0.105,H,A,0.48,-1.18,0.878,,65.53,PHH,-2.205,0.295029,0.00836567,0.691354 E1_Ubiquitin_T68E,E1_Ubiquitin_68,Uba1,E1_Ubiquitin,P0CG63,0.691424,NO,68,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,,,,,,,,,,,,,OPH,-1.039,0.18783,0.00314321,0.691424 kka2_1:8_G213V,kka2_1:8_213,Kka2,kka2_1:8,P00552,0.691425,NO,213,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.596,-3.782,3.186,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.100394,0.00187654,0.691425 kka2_1:8_G213V,kka2_1:8_213,Kka2,kka2_1:8,P00552,0.691425,NO,213,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.596,-3.782,3.186,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.100394,0.00187654,0.691425 kka2_1:1_S40H,kka2_1:1_40,Kka2,kka2_1:1,P00552,0.69143,NO,40,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.645,-3.006,0.361,,0.32,E,B,0.27,-0.9,25.997,25.997,71.59,HPH,-1.91567,0.520039,0.00693477,0.69143 beta-lactamase_A245V,beta-lactamase_245,TEM-1,beta-lactamase,P62593,0.691477,NO,245,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.068,-2.56,1.492,4.78972,,E,B,0.17,-0.92,0.831,,64.69,HHH,-1.58133,0.221079,0.00391032,0.691477 kka2_1:1_L70C,kka2_1:1_70,Kka2,kka2_1:1,P00552,0.69152,NO,70,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.017,-4.768,3.751,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.520039,0.00411884,0.69152 beta-lactamase_F70Y,beta-lactamase_70,TEM-1,beta-lactamase,P62593,0.69153,NO,70,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.169,-2.563,1.394,5.42055,,H,A,1.1,-1.34,1.14,,63.99,PHB,-0.980667,0.221079,0.00193499,0.69153 beta-lactamase_0_Y95A,beta-lactamase_0_95,TEM-1,beta-lactamase_0,P62593,0.691584,NO,95,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-1.715,-3.364,1.649,,0.122,,b,0.21,-0.37,2.914,,77.62,BHP,-2.16167,0.0500837,0.00479449,0.691584 kka2_1:2_Q100L,kka2_1:2_100,Kka2,kka2_1:2,P00552,0.691648,NO,100,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.77,-2.853,0.083,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.295029,0.0066405,0.691648 kka2_1:1_I246V,kka2_1:1_246,Kka2,kka2_1:1,P00552,0.691683,NO,246,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-2.008,-2.046,0.038,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.520039,0.0139479,0.691683 kka2_1:2_T73W,kka2_1:2_73,Kka2,kka2_1:2,P00552,0.691736,NO,73,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.51,-5.397,2.887,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.295029,0.00628605,0.691736 beta-lactamase_0_G142T,beta-lactamase_0_142,TEM-1,beta-lactamase_0,P62593,0.691748,NO,142,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.707,-3.568,2.861,,0.034,,p,0.29,-0.64,1.947,,64.69,OOO,-0.834,0.0500837,0.00060149,0.691748 beta-lactamase_2500_P250D,beta-lactamase_2500_250,TEM-1,beta-lactamase_2500,P62593,0.691763,NO,250,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-2.335,-1.83,-0.505,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.361275,0.00550899,0.691763 beta-lactamase_0_T187I,beta-lactamase_0_187,TEM-1,beta-lactamase_0,P62593,0.691781,NO,187,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.401,-2.871,1.47,,0.007,H,A,0.22,-1.19,3.259,,67.48,PPH,-1.69633,0.0500837,0.00491782,0.691781 kka2_1:4_L70P,kka2_1:4_70,Kka2,kka2_1:4,P00552,0.691797,NO,70,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.017,-4.164,3.147,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.168804,0.00411884,0.691797 kka2_1:1_G95V,kka2_1:1_95,Kka2,kka2_1:1,P00552,0.691823,NO,95,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-2.403,-2.997,0.594,,0.126,E,B,0.29,-0.74,7.822,,71.59,HOA,-2.198,0.520039,0.00743616,0.691823 kka2_1:1_A137S,kka2_1:1_137,Kka2,kka2_1:1,P00552,0.691839,NO,137,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.156,-2.895,0.739,,0.029,H,A,0.46,0.34,1.323,,63.26,PHB,-2.559,0.520039,0.00515054,0.691839 beta-lactamase_2500_T269Y,beta-lactamase_2500_269,TEM-1,beta-lactamase_2500,P62593,0.691983,NO,269,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.361275,0.00950944,0.691983 PSD95pdz3_I316D,PSD95pdz3_316,PSD95pdz3,PSD95pdz3,P31016,0.691994,NO,316,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.63,-3.6,1.97,5.46166,,,,,19.005,,,,HHB,-1.62733,0.0758425,0.00112762,0.691994 kka2_1:4_P109R,kka2_1:4_109,Kka2,kka2_1:4,P00552,0.691996,NO,109,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.412,-3.997,2.585,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.168804,0.0070929,0.691996 WW_domain_D201G,WW_domain_201,Yap65,WW_domain,P46937,0.692054,NO,201,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.369,-3.115,1.746,4.90312,,,,,,20.806,20.806,70.04,PAO,-1.456,0.153962,0.00248402,0.692054 beta-lactamase_A23R,beta-lactamase_23,TEM-1,beta-lactamase,P62593,0.692055,NO,23,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.548,-3.898,2.35,,,,,,,0.801,,93.01,HHB,-2.235,0.221079,0.00245563,0.692055 kka2_1:1_A176S,kka2_1:1_176,Kka2,kka2_1:1,P00552,0.692097,NO,176,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.621,-1.88,0.259,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.520039,0.0083587,0.692097 beta-lactamase_156_I244N,beta-lactamase_156_244,TEM-1,beta-lactamase_156,P62593,0.692138,NO,244,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.555,-4.114,2.559,,,E,B,0.48,-0.84,1.325,,77.62,OHH,-1.385,0.111618,0.00605379,0.692138 kka2_1:2_D90A,kka2_1:2_90,Kka2,kka2_1:2,P00552,0.692384,NO,90,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.459,-3.423,0.964,,0.104,E,B,0.75,0.73,6.085,,64.39,BAH,-1.72833,0.295029,0.00583842,0.692384 kka2_1:1_I29M,kka2_1:1_29,Kka2,kka2_1:1,P00552,0.692408,NO,29,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.692,-3.049,1.357,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.520039,0.00619521,0.692408 beta-lactamase_0_I125E,beta-lactamase_0_125,TEM-1,beta-lactamase_0,P62593,0.692454,NO,125,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.441,-3.878,2.437,,,H,A,0.48,-0.7,1.874,,63.29,HHP,-1.248,0.0500837,0.00383964,0.692454 kka2_1:2_D154M,kka2_1:2_154,Kka2,kka2_1:2,P00552,0.692472,NO,154,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.876,-4.959,4.083,,0.457,,b,0.29,1.48,3.631,,52.65,HAP,-1.52467,0.295029,0.00292633,0.692472 kka2_1:2_P128Q,kka2_1:2_128,Kka2,kka2_1:2,P00552,0.692477,NO,128,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.922,-4.314,2.392,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.295029,0.00774689,0.692477 kka2_1:8_E262K,kka2_1:8_262,Kka2,kka2_1:8,P00552,0.692517,NO,262,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-0.829,-3.058,2.229,,0.059,G,A,1.52,-0.18,0.837,,42.42,AAH,-0.816,0.100394,0.0191586,0.692517 kka2_1:8_E262K,kka2_1:8_262,Kka2,kka2_1:8,P00552,0.692517,NO,262,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-0.829,-3.058,2.229,,0.059,G,A,1.52,-0.18,0.837,,42.42,AAH,-0.816,0.100394,0.0191586,0.692517 kka2_1:8_L39P,kka2_1:8_39,Kka2,kka2_1:8,P00552,0.692517,NO,39,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.223,-4.188,2.965,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.100394,0.00493618,0.692517 kka2_1:8_L39P,kka2_1:8_39,Kka2,kka2_1:8,P00552,0.692517,NO,39,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.223,-4.188,2.965,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.100394,0.00493618,0.692517 gb1_G235M,gb1_235,gb1,gb1,P06654,0.692572,NO,235,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.419,-4.491,3.072,,,,,,,0.476,,11.83,POB,-1.86433,0.177985,0.00297491,0.692572 beta-lactamase_0_I125M,beta-lactamase_0_125,TEM-1,beta-lactamase_0,P62593,0.692627,NO,125,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.441,-2.597,1.156,,,H,A,0.48,-0.7,1.874,,63.29,HHP,-1.248,0.0500837,0.00383964,0.692627 beta-lactamase_39_L136Q,beta-lactamase_39_136,TEM-1,beta-lactamase_39,P62593,0.692668,NO,136,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.232,-4.242,3.01,,,H,A,0.55,-0.34,0.336,,48.95,HHH,-1.088,0.0495842,0.00442304,0.692668 kka2_1:8_L193I,kka2_1:8_193,Kka2,kka2_1:8,P00552,0.692726,NO,193,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.983,-3.143,2.16,,,G,A,1.59,-1.03,2.234,,65.53,OHO,-0.965333,0.100394,0.00480179,0.692726 kka2_1:8_L193I,kka2_1:8_193,Kka2,kka2_1:8,P00552,0.692726,NO,193,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.983,-3.143,2.16,,,G,A,1.59,-1.03,2.234,,65.53,OHO,-0.965333,0.100394,0.00480179,0.692726 kka2_1:8_R253F,kka2_1:8_253,Kka2,kka2_1:8,P00552,0.692768,NO,253,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.356,-4.389,3.033,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.100394,0.0144195,0.692768 kka2_1:8_R253F,kka2_1:8_253,Kka2,kka2_1:8,P00552,0.692768,NO,253,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.356,-4.389,3.033,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.100394,0.0144195,0.692768 beta-lactamase_625_K30W,beta-lactamase_625_30,TEM-1,beta-lactamase_625,P62593,0.692807,NO,30,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-2.307,-5.404,3.097,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.213352,0.00448593,0.692807 kka2_1:2_A119E,kka2_1:2_119,Kka2,kka2_1:2,P00552,0.693026,NO,119,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.073,-3.557,2.484,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.295029,0.00441074,0.693026 beta-lactamase_0_G253D,beta-lactamase_0_253,TEM-1,beta-lactamase_0,P62593,0.693174,NO,253,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.0500837,0.00786358,0.693174 kka2_1:1_R226L,kka2_1:1_226,Kka2,kka2_1:1,P00552,0.693327,NO,226,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.392,-3.592,2.2,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.520039,0.0108032,0.693327 beta-lactamase_0_Y103L,beta-lactamase_0_103,TEM-1,beta-lactamase_0,P62593,0.693371,NO,103,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-1.33,-3.402,2.072,,0.613,S,l,0.21,1.21,1.646,,63.29,AHP,-1.48767,0.0500837,0.00443048,0.693371 beta-lactamase_2500_M153Y,beta-lactamase_2500_153,TEM-1,beta-lactamase_2500,P62593,0.693413,NO,153,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-3.193,-4.187,0.994,,0.14,T,A,0.55,-0.11,3.409,,77.62,PHO,-2.25767,0.361275,0.00509109,0.693413 kka2_1:2_T28C,kka2_1:2_28,Kka2,kka2_1:2,P00552,0.693454,NO,28,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.883,-5.036,3.153,,0.353,S,B,0.22,2.02,2.655,,63.64,PPH,-1.74467,0.295029,0.00743084,0.693454 kka2_1:1_D82Y,kka2_1:1_82,Kka2,kka2_1:1,P00552,0.693488,NO,82,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.946,-4.406,2.46,,0.341,E,b,0.75,0.52,11.345,11.345,63.64,HAH,-1.98,0.520039,0.00637516,0.693488 Ubiquitin_I13Y,Ubiquitin_13,Uba1,Ubiquitin,P0CG48,0.693548,NO,13,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.554,-2.853,1.299,5.19411,0.038,E,B,,-0.2,,,,PHP,-1.48,0.205827,0.000716423,0.693548 Ubiquitin_I30S,Ubiquitin_30,Uba1,Ubiquitin,P0CG48,0.693548,NO,30,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.205,-2.603,1.398,4.80264,,H,A,,-0.51,,,,BHP,-1.45133,0.205827,0.000720128,0.693548 Ubiquitin_Q2T,Ubiquitin_2,Uba1,Ubiquitin,P0CG48,0.693548,NO,2,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-1.7,-2.387,0.687,4.89203,0.475,E,B,,0.1,,,,OPH,-1.551,0.205827,0.00085006,0.693548 Ubiquitin_R42C,Ubiquitin_42,Uba1,Ubiquitin,P0CG48,0.693548,NO,42,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.571,-3.126,1.555,5.07805,0.244,E,B,0.68,-0.54,1.976,,72.85,PBH,-1.38967,0.205827,0.000622265,0.693548 Ubiquitin_T7H,Ubiquitin_7,Uba1,Ubiquitin,P0CG48,0.693548,NO,7,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.415,-4.684,3.269,4.954,0.094,E,B,0.43,-0.78,0.805,,21.31,BPH,-1.41033,0.205827,0.000647855,0.693548 beta-lactamase_0_V72H,beta-lactamase_0_72,TEM-1,beta-lactamase_0,P62593,0.693583,NO,72,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.658,-4.908,3.25,,,H,A,0.44,-1.03,2.964,,65.73,BHH,-1.32167,0.0500837,0.00501194,0.693583 beta-lactamase_39_I140P,beta-lactamase_39_140,TEM-1,beta-lactamase_39,P62593,0.693591,NO,140,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.733,-4.152,2.419,,0.128,H,A,0.48,0.41,1.16,,73.08,PHO,-1.48733,0.0495842,0.00597777,0.693591 PSD95pdz3_F325H,PSD95pdz3_325,PSD95pdz3,PSD95pdz3,P31016,0.693596,NO,325,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.524,-4.137,2.613,5.50654,,,,,12.7236,,,,OHP,-1.314,0.0758425,0.00102273,0.693596 kka2_1:8_A237M,kka2_1:8_237,Kka2,kka2_1:8,P00552,0.693604,NO,237,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.12,-4.281,2.161,,0.068,H,A,0.46,-0.71,0.449,,92.05,HHA,-2.10433,0.100394,0.012257,0.693604 kka2_1:8_A237M,kka2_1:8_237,Kka2,kka2_1:8,P00552,0.693604,NO,237,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.12,-4.281,2.161,,0.068,H,A,0.46,-0.71,0.449,,92.05,HHA,-2.10433,0.100394,0.012257,0.693604 gb1_A252I,gb1_252,gb1,gb1,P06654,0.693656,NO,252,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.175,-3.296,2.121,,,,,,,,,,PHA,-1.55967,0.177985,0.00125598,0.693656 kka2_1:4_G245A,kka2_1:4_245,Kka2,kka2_1:4,P00552,0.693683,NO,245,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.812,-2.418,1.606,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.168804,0.00683899,0.693683 beta-lactamase_R91G,beta-lactamase_91,TEM-1,beta-lactamase,P62593,0.69382,NO,91,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.392,-3.437,2.045,5.92536,0.444,,B,0.68,0.96,1.318,,50.35,OBB,-1.73367,0.221079,0.00380226,0.69382 kka2_1:1_T225S,kka2_1:1_225,Kka2,kka2_1:1,P00552,0.69385,NO,225,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.393,-2.531,0.138,,0.036,H,A,0.22,-1.22,4.554,,63.64,HPB,-1.58733,0.520039,0.0113598,0.69385 beta-lactamase_156_I258G,beta-lactamase_156_258,TEM-1,beta-lactamase_156,P62593,0.693938,NO,258,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.111618,0.007931,0.693938 kka2_1:4_P194V,kka2_1:4_194,Kka2,kka2_1:4,P00552,0.693969,NO,194,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.846,-3.62,2.774,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.168804,0.00314194,0.693969 kka2_1:1_Q163E,kka2_1:1_163,Kka2,kka2_1:1,P00552,0.694012,NO,163,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.162,-2.572,0.41,,0.58,T,B,0.64,1.85,2.779,,64.02,BPO,-1.78333,0.520039,0.00719507,0.694012 kka2_1:4_V198M,kka2_1:4_198,Kka2,kka2_1:4,P00552,0.694284,NO,198,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.719,-3.281,1.562,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.168804,0.00835002,0.694284 beta-lactamase_L191H,beta-lactamase_191,TEM-1,beta-lactamase,P62593,0.69432,NO,191,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.087,-4.898,3.811,5.72226,,H,A,1.07,0.09,1.23,,63.29,BHH,-1.445,0.221079,0.00263549,0.69432 Pab1_H172A,Pab1_172,Pab1,Pab1,P04147,0.694356,NO,172,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-1.21,-3.12,1.91,,0.076,E,B,0.35,-0.87,,,,HBH,-1.26667,0.175299,0.000296642,0.694356 kka2_1:1_P109T,kka2_1:1_109,Kka2,kka2_1:1,P00552,0.694382,NO,109,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.412,-2.893,1.481,,0.376,H,A,0.52,-1.25,18.506,18.506,65.53,HOH,-1.84567,0.520039,0.0070929,0.694382 kka2_1:2_Y257C,kka2_1:2_257,Kka2,kka2_1:2,P00552,0.694475,NO,257,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-1.064,-4.949,3.885,,0.022,H,A,0.21,-0.88,0.833,,52.65,HHB,-1.39333,0.295029,0.0148191,0.694475 beta-lactamase_625_R91G,beta-lactamase_625_91,TEM-1,beta-lactamase_625,P62593,0.694506,NO,91,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.392,-3.437,2.045,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.213352,0.00380226,0.694506 kka2_1:2_A150D,kka2_1:2_150,Kka2,kka2_1:2,P00552,0.694567,NO,150,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.949,-3.619,2.67,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.295029,0.0045009,0.694567 beta-lactamase_0_R257E,beta-lactamase_0_257,TEM-1,beta-lactamase_0,P62593,0.694584,NO,257,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.0500837,0.00756629,0.694584 beta-lactamase_0_G39F,beta-lactamase_0_39,TEM-1,beta-lactamase_0,P62593,0.694588,NO,39,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.864,-4.451,2.587,,0.701,T,L,0.29,0.47,4.111,,77.62,HOH,-1.53633,0.0500837,0.00487611,0.694588 kka2_1:4_H124D,kka2_1:4_124,Kka2,kka2_1:4,P00552,0.694598,NO,124,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-0.84,-3.497,2.657,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.168804,0.00211296,0.694598 PSD95pdz3_I336S,PSD95pdz3_336,PSD95pdz3,PSD95pdz3,P31016,0.694649,NO,336,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.63,-3.292,1.662,5.11321,,,,,13.6363,,,,OHH,-1.38733,0.0758425,0.000887923,0.694649 kka2_1:1_G189C,kka2_1:1_189,Kka2,kka2_1:1,P00552,0.694698,NO,189,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.596,-5.115,4.519,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.520039,0.00253688,0.694698 beta-lactamase_S264V,beta-lactamase_264,TEM-1,beta-lactamase,P62593,0.694714,NO,264,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.985,-2.851,0.866,4.67475,0.04,,B,0.25,0.29,34.251,34.251,73.78,OPP,-2.19867,0.221079,0.0119399,0.694714 kka2_1:2_K112E,kka2_1:2_112,Kka2,kka2_1:2,P00552,0.694723,NO,112,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-2.491,-3.666,1.175,,0.076,H,A,2.34,-1.37,23.433,23.433,56.06,ABH,-2.00133,0.295029,0.00645389,0.694723 kka2_1:8_I221C,kka2_1:8_221,Kka2,kka2_1:8,P00552,0.694727,NO,221,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.739,-4.79,3.051,,,H,A,1.52,-1.15,1.599,,71.59,AHH,-1.08367,0.100394,0.00945908,0.694727 kka2_1:8_I221C,kka2_1:8_221,Kka2,kka2_1:8,P00552,0.694727,NO,221,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.739,-4.79,3.051,,,H,A,1.52,-1.15,1.599,,71.59,AHH,-1.08367,0.100394,0.00945908,0.694727 beta-lactamase_156_I140K,beta-lactamase_156_140,TEM-1,beta-lactamase_156,P62593,0.69473,NO,140,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.733,-3.879,2.146,,0.128,H,A,0.48,0.41,1.16,,73.08,PHO,-1.48733,0.111618,0.00597777,0.69473 gb1_F256N,gb1_256,gb1,gb1,P06654,0.694732,NO,256,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.241,-3.9,2.659,,,,,,,,,,HHB,-2.04767,0.177985,0.00435993,0.694732 gb1_N263E,gb1_263,gb1,gb1,P06654,0.694732,NO,263,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-1.162,-2.992,1.83,,,,,,,,,,APO,-2.04233,0.177985,0.0035297,0.694732 beta-lactamase_L89N,beta-lactamase_89,TEM-1,beta-lactamase,P62593,0.694736,NO,89,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.096,-4.11,3.014,5.41092,0.168,T,A,1.75,0.63,1.599,,64.34,PHO,-1.75767,0.221079,0.00207068,0.694736 kka2_1:2_P167D,kka2_1:2_167,Kka2,kka2_1:2,P00552,0.694911,NO,167,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-2.403,-3.015,0.612,,0.18,H,A,0.52,0.75,3.6,,64.39,HOH,-2.26633,0.295029,0.00543203,0.694911 beta-lactamase_0_S80N,beta-lactamase_0_80,TEM-1,beta-lactamase_0,P62593,0.695056,NO,80,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.029,-2.999,0.97,,0.192,H,A,0.27,0.46,12.403,12.403,77.62,HPB,-1.44567,0.0500837,0.00565569,0.695056 beta-lactamase_G76L,beta-lactamase_76,TEM-1,beta-lactamase,P62593,0.695102,NO,76,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.189,-3.521,2.332,4.73862,,H,A,2.05,-0.67,3.059,,67.83,OOH,-1.22267,0.221079,0.00476637,0.695102 Pab1_I196S,Pab1_196,Pab1,Pab1,P04147,0.695241,NO,196,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.795,-3.503,1.708,,,,,,,2.013,,80.59,AHH,-1.44667,0.175299,0.0016933,0.695241 beta-lactamase_2500_A34W,beta-lactamase_2500_34,TEM-1,beta-lactamase_2500,P62593,0.695291,NO,34,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.059,-2.89,0.831,,,H,A,0.46,-0.54,2.921,,73.78,AHA,-1.74967,0.361275,0.00407913,0.695291 kka2_1:1_I29S,kka2_1:1_29,Kka2,kka2_1:1,P00552,0.69535,NO,29,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.692,-3.624,1.932,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.520039,0.00619521,0.69535 WW_domain_N191D,WW_domain_191,Yap65,WW_domain,P46937,0.695361,NO,191,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-1.519,-3.07,1.551,5.96016,,,,,,5.117,,66.07,HPB,-1.554,0.153962,0.00270999,0.695361 kka2_1:4_L123V,kka2_1:4_123,Kka2,kka2_1:4,P00552,0.695464,NO,123,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.888,-2.888,2,,0.007,H,A,0.55,-0.4,1.447,,48.86,BHB,-1.301,0.168804,0.00325188,0.695464 beta-lactamase_39_V72W,beta-lactamase_39_72,TEM-1,beta-lactamase_39,P62593,0.695474,NO,72,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.658,-3.279,1.621,,,H,A,0.44,-1.03,1.92,,65.73,BHH,-1.32167,0.0495842,0.00501194,0.695474 beta-lactamase_G239S,beta-lactamase_239,TEM-1,beta-lactamase,P62593,0.695515,NO,239,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.819,-3.137,2.318,4.85529,0.115,T,l,0.77,-0.62,1.817,,42.31,BOP,-1.45267,0.221079,0.00213852,0.695515 beta-lactamase_E164Y,beta-lactamase_164,TEM-1,beta-lactamase,P62593,0.695645,NO,164,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-0.948,-4.233,3.285,5.3334,0.011,T,B,1.62,-0.4,1.055,,64.69,HAO,-1.388,0.221079,0.00137286,0.695645 kka2_1:4_V113C,kka2_1:4_113,Kka2,kka2_1:4,P00552,0.695674,NO,113,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.233,-4.781,3.548,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.168804,0.00650191,0.695674 kka2_1:1_I115V,kka2_1:1_115,Kka2,kka2_1:1,P00552,0.695732,NO,115,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.606,-2.022,0.416,,0.105,H,A,0.48,-1.18,0.878,,65.53,PHH,-2.205,0.520039,0.00836567,0.695732 beta-lactamase_0_T158E,beta-lactamase_0_158,TEM-1,beta-lactamase_0,P62593,0.69578,NO,158,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.116,-3.449,2.333,,0.036,,B,0.22,-0.85,1.041,,69.58,HPB,-1.269,0.0500837,0.00341825,0.69578 beta-lactamase_0_V259K,beta-lactamase_0_259,TEM-1,beta-lactamase_0,P62593,0.695798,NO,259,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.0500837,0.0070773,0.695798 gb1_Y229T,gb1_229,gb1,gb1,P06654,0.695801,NO,229,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-1.282,-3.382,2.1,,,,,,,,,,PHB,-1.4915,0.177985,0.00366605,0.695801 beta-lactamase_0_L218C,beta-lactamase_0_218,TEM-1,beta-lactamase_0,P62593,0.695806,NO,218,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.391,-4.928,3.537,,,I,b,0.55,-0.53,28.707,28.707,74.48,OHH,-1.58867,0.0500837,0.00618274,0.695806 kka2_1:4_L67A,kka2_1:4_67,Kka2,kka2_1:4,P00552,0.695917,NO,67,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.741,-3.106,2.365,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.168804,0.00102787,0.695917 beta-lactamase_A124I,beta-lactamase_124,TEM-1,beta-lactamase,P62593,0.69595,NO,124,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.181,-3.529,2.348,4.58507,,H,A,0.58,-0.9,2.273,,64.34,HHH,-1.152,0.221079,0.00481399,0.69595 beta-lactamase_0_Y103N,beta-lactamase_0_103,TEM-1,beta-lactamase_0,P62593,0.695972,NO,103,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-1.33,-2.825,1.495,,0.613,S,l,0.21,1.21,1.646,,63.29,AHP,-1.48767,0.0500837,0.00443048,0.695972 beta-lactamase_2500_A40M,beta-lactamase_2500_40,TEM-1,beta-lactamase_2500,P62593,0.695972,NO,40,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.402,-4.684,3.282,,0.155,S,B,0.46,0.21,0.953,,73.78,OHB,-1.40267,0.361275,0.00490026,0.695972 beta-lactamase_0_T116C,beta-lactamase_0_116,TEM-1,beta-lactamase_0,P62593,0.695989,NO,116,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.28,-4.831,3.551,,0.115,E,B,0.22,-0.12,1.356,,67.48,HPH,-1.39967,0.0500837,0.00336175,0.695989 beta-lactamase_156_L74G,beta-lactamase_156_74,TEM-1,beta-lactamase_156,P62593,0.695992,NO,74,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.296,-3.477,2.181,,,H,A,0.55,-0.91,0.746,,50,HHO,-1.34933,0.111618,0.00493255,0.695992 kka2_1:4_D134Y,kka2_1:4_134,Kka2,kka2_1:4,P00552,0.696081,NO,134,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.969,-4.401,3.432,,0.421,B,B,0.75,0.31,0.733,,49.62,HAB,-1.057,0.168804,0.00270812,0.696081 beta-lactamase_0_L248N,beta-lactamase_0_248,TEM-1,beta-lactamase_0,P62593,0.696102,NO,248,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.0500837,0.00428493,0.696102 Pab1_H172L,Pab1_172,Pab1,Pab1,P04147,0.696173,NO,172,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-1.21,-3.4,2.19,,0.076,E,B,0.35,-0.87,,,,HBH,-1.26667,0.175299,0.000296642,0.696173 beta-lactamase_0_A40W,beta-lactamase_0_40,TEM-1,beta-lactamase_0,P62593,0.696253,NO,40,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.402,-5.298,3.896,,0.155,S,B,0.46,0.21,0.783,,73.78,OHB,-1.40267,0.0500837,0.00490026,0.696253 kka2_1:8_W15K,kka2_1:8_15,Kka2,kka2_1:8,P00552,0.696335,NO,15,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-1.392,-3.944,2.552,,0.01,G,A,1.51,0.15,0.827,,52.27,HHH,-2.10533,0.100394,0.00585505,0.696335 kka2_1:8_W15K,kka2_1:8_15,Kka2,kka2_1:8,P00552,0.696335,NO,15,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-1.392,-3.944,2.552,,0.01,G,A,1.51,0.15,0.827,,52.27,HHH,-2.10533,0.100394,0.00585505,0.696335 kka2_1:8_Y22R,kka2_1:8_22,Kka2,kka2_1:8,P00552,0.696474,NO,22,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-1.583,-3.13,1.547,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.100394,0.00598977,0.696474 kka2_1:8_Y22R,kka2_1:8_22,Kka2,kka2_1:8,P00552,0.696474,NO,22,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-1.583,-3.13,1.547,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.100394,0.00598977,0.696474 WW_domain_G185S,WW_domain_185,Yap65,WW_domain,P46937,0.69658,NO,185,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.861,-2.938,2.077,6.22337,,,,,,,,,POP,-1.194,0.153962,0.00199178,0.69658 beta-lactamase_G279V,beta-lactamase_279,TEM-1,beta-lactamase,P62593,0.696674,NO,279,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.038,-3.59,2.552,4.53882,,H,A,0.46,-0.97,3.066,,62.59,HOH,-1.36467,0.221079,0.0192826,0.696674 E1_Ubiquitin_I44C,E1_Ubiquitin_44,Uba1,E1_Ubiquitin,P0CG63,0.696729,NO,44,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.432,-4.624,3.192,,,E,B,0.27,-1.17,4.57,,78.74,HHH,-1.25633,0.18783,0.00209731,0.696729 E1_Ubiquitin_L73G,E1_Ubiquitin_73,Uba1,E1_Ubiquitin,P0CG63,0.696729,NO,73,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.039,-3.625,2.586,,0.518,,B,1.3,1,,,,BHB,-1.175,0.18783,0.00111236,0.696729 kka2_1:1_Q219K,kka2_1:1_219,Kka2,kka2_1:1,P00552,0.696806,NO,219,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-0.93,-3.033,2.103,,0.088,H,A,0.4,-0.85,1.917,,50,HPA,-1.05167,0.520039,0.00237913,0.696806 beta-lactamase_625_R220Q,beta-lactamase_625_220,TEM-1,beta-lactamase_625,P62593,0.696844,NO,220,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-0.942,-3.517,2.575,,0.295,I,A,1.2,-0.76,5.086,,74.48,HBP,-1.33633,0.213352,0.00232421,0.696844 kka2_1:2_P179R,kka2_1:2_179,Kka2,kka2_1:2,P00552,0.696931,NO,179,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.974,-4.006,3.032,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.295029,0.00298346,0.696931 beta-lactamase_2500_E62A,beta-lactamase_2500_62,TEM-1,beta-lactamase_2500,P62593,0.69696,NO,62,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.193,-2.533,1.34,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.361275,0.00264802,0.69696 kka2_1:4_L107H,kka2_1:4_107,Kka2,kka2_1:4,P00552,0.696995,NO,107,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.238,-4.994,3.756,,0.197,.,B,0.55,-1.1,0.398,,71.59,BHH,-2.143,0.168804,0.00561937,0.696995 beta-lactamase_2500_S233A,beta-lactamase_2500_233,TEM-1,beta-lactamase_2500,P62593,0.697006,NO,233,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.886,-2.424,0.538,,0.016,E,B,0.27,-1.01,2.851,,77.62,BPO,-1.17267,0.361275,0.00311415,0.697006 kka2_1:1_M1T,kka2_1:1_1,Kka2,kka2_1:1,P00552,0.697091,NO,1,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.787,-3.152,1.365,,,,,,,3.101,,62.12,NAHH,-1.787,0.520039,0.00251939,0.697091 beta-lactamase_0_S256W,beta-lactamase_0_256,TEM-1,beta-lactamase_0,P62593,0.697119,NO,256,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.0500837,0.00710634,0.697119 beta-lactamase_0_L150V,beta-lactamase_0_150,TEM-1,beta-lactamase_0,P62593,0.697174,NO,150,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.326,-2.348,1.022,,,H,A,0.55,-0.2,2.128,,62.94,HHB,-1.86167,0.0500837,0.00463171,0.697174 kka2_1:1_G30C,kka2_1:1_30,Kka2,kka2_1:1,P00552,0.697225,NO,30,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.596,-5.115,4.519,,0.54,S,g,0.29,3.76,,,,HOO,-1.51133,0.520039,0.00159208,0.697225 beta-lactamase_Y95H,beta-lactamase_95,TEM-1,beta-lactamase,P62593,0.69723,NO,95,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-1.715,-3.182,1.467,5.67068,0.122,,b,0.96,-0.37,2.341,,77.62,BHP,-2.16167,0.221079,0.00479449,0.69723 Pab1_K131C,Pab1_131,Pab1,Pab1,P04147,0.697262,NO,131,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.083,-4.904,3.821,,0.462,E,B,1.82,0.57,,,,HBP,-1.12467,0.175299,0.000349395,0.697262 kka2_1:4_A34V,kka2_1:4_34,Kka2,kka2_1:4,P00552,0.697266,NO,34,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.928,-3.231,2.303,,0.417,.,B,0.46,2.29,0.262,,52.27,AHH,-1.747,0.168804,0.00343484,0.697266 kka2_1:2_R147C,kka2_1:2_147,Kka2,kka2_1:2,P00552,0.697318,NO,147,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.123,-5.216,4.093,,0.094,H,A,1.2,0.97,0.425,,64.02,PBH,-1.98267,0.295029,0.00549168,0.697318 kka2_1:1_Q155H,kka2_1:1_155,Kka2,kka2_1:1,P00552,0.697459,NO,155,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.606,-4.51,1.904,,0.525,T,A,0.4,1.49,4.415,,63.64,APA,-1.726,0.520039,0.00641853,0.697459 beta-lactamase_2500_F228T,beta-lactamase_2500_228,TEM-1,beta-lactamase_2500,P62593,0.697524,NO,228,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-2.342,-2.522,0.18,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.361275,0.0046669,0.697524 beta-lactamase_0_D161R,beta-lactamase_0_161,TEM-1,beta-lactamase_0,P62593,0.697526,NO,161,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.891,-3.902,3.011,,0.341,,A,0.75,-0.52,0.795,,61.19,HAB,-0.961333,0.0500837,0.000897697,0.697526 kka2_1:4_G205A,kka2_1:4_205,Kka2,kka2_1:4,P00552,0.697527,NO,205,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.596,-2.881,2.285,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.168804,0.00221855,0.697527 beta-lactamase_P181S,beta-lactamase_181,TEM-1,beta-lactamase,P62593,0.697549,NO,181,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.813,-3.349,2.536,5.14752,,H,A,1.1,-1.14,1.357,,61.54,HOH,-1.795,0.221079,0.000703122,0.697549 kka2_1:1_M116V,kka2_1:1_116,Kka2,kka2_1:1,P00552,0.697593,NO,116,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-2.482,-2.282,-0.2,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.520039,0.00745147,0.697593 kka2_1:1_G234C,kka2_1:1_234,Kka2,kka2_1:1,P00552,0.697691,NO,234,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-2.9,-5.225,2.325,,0.494,H,A,0.29,-0.29,1.753,,71.59,OOA,-1.86767,0.520039,0.00984449,0.697691 kka2_1:4_G245V,kka2_1:4_245,Kka2,kka2_1:4,P00552,0.697691,NO,245,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.812,-3.749,2.937,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.168804,0.00683899,0.697691 PSD95pdz3_P346W,PSD95pdz3_346,PSD95pdz3,PSD95pdz3,P31016,0.69779,NO,346,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.236,-5.229,3.993,5.02406,,,,,14.6629,,,,OOH,-1.18367,0.0758425,0.000758563,0.69779 kka2_1:2_H124D,kka2_1:2_124,Kka2,kka2_1:2,P00552,0.697849,NO,124,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-0.84,-3.497,2.657,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.295029,0.00211296,0.697849 beta-lactamase_0_I125C,beta-lactamase_0_125,TEM-1,beta-lactamase_0,P62593,0.697852,NO,125,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.441,-4.783,3.342,,,H,A,0.48,-0.7,1.874,,63.29,HHP,-1.248,0.0500837,0.00383964,0.697852 kka2_1:8_G95F,kka2_1:8_95,Kka2,kka2_1:8,P00552,0.697879,NO,95,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-2.403,-4.378,1.975,,0.126,E,B,0.75,-0.74,7.774,,71.59,HOA,-2.198,0.100394,0.00743616,0.697879 kka2_1:8_G95F,kka2_1:8_95,Kka2,kka2_1:8,P00552,0.697879,NO,95,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-2.403,-4.378,1.975,,0.126,E,B,0.75,-0.74,7.774,,71.59,HOA,-2.198,0.100394,0.00743616,0.697879 PSD95pdz3_L367G,PSD95pdz3_367,PSD95pdz3,PSD95pdz3,P31016,0.697952,NO,367,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.347,-3.49,2.143,5.47696,,,,,17.0063,,,,AHB,-1.39767,0.0758425,0.000466436,0.697952 beta-lactamase_0_H151Y,beta-lactamase_0_151,TEM-1,beta-lactamase_0,P62593,0.697965,NO,151,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-2.96,-4.115,1.155,,0.594,H,A,0.17,0.1,9.375,,77.62,HBP,-2.34767,0.0500837,0.00216946,0.697965 kka2_1:4_A237S,kka2_1:4_237,Kka2,kka2_1:4,P00552,0.698053,NO,237,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.12,-3.575,1.455,,0.068,H,A,0.46,-0.71,2.444,,92.05,HHA,-2.10433,0.168804,0.012257,0.698053 beta-lactamase_I93E,beta-lactamase_93,TEM-1,beta-lactamase,P62593,0.698057,NO,93,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.401,-3.886,2.485,5.74695,0.128,E,B,0.77,0.44,1.757,,67.83,BHB,-1.873,0.221079,0.00527066,0.698057 beta-lactamase_G52W,beta-lactamase_52,TEM-1,beta-lactamase,P62593,0.698088,NO,52,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.149,-5.364,4.215,5.12093,0.299,,l,0.77,-0.04,2.103,,64.69,POB,-1.66267,0.221079,0.00340138,0.698088 kka2_1:2_G74R,kka2_1:2_74,Kka2,kka2_1:2,P00552,0.698109,NO,74,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.18,-3.943,2.763,,0.621,T,l,0.75,0.2,1.446,,64.39,POH,-1.91667,0.295029,0.00587035,0.698109 beta-lactamase_C121S,beta-lactamase_121,TEM-1,beta-lactamase,P62593,0.698167,NO,121,C,S,CS,Special,Polar,5.07,5.68,0.61,112,121,105,-16,108.5,89,-19.5,-0.953,-3.411,2.458,5.12205,,H,A,2.8,-0.81,7.644,,63.29,HOP,-1.46767,0.221079,0.000744322,0.698167 beta-lactamase_R162L,beta-lactamase_162,TEM-1,beta-lactamase,P62593,0.698167,NO,162,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.016,-2.541,1.525,5.34456,0.124,S,B,0.68,-0.37,31.656,31.656,64.69,ABH,-1.25,0.221079,0.000561334,0.698167 kka2_1:2_P12D,kka2_1:2_12,Kka2,kka2_1:2,P00552,0.6982,NO,12,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.853,-3.54,2.687,,,.,B,0.52,1.25,0.261,,48.11,POH,-1.80767,0.295029,0.00500011,0.6982 kka2_1:8_E96D,kka2_1:8_96,Kka2,kka2_1:8,P00552,0.698291,NO,96,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.573,-3.69,1.117,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.100394,0.00369441,0.698291 kka2_1:8_E96D,kka2_1:8_96,Kka2,kka2_1:8,P00552,0.698291,NO,96,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.573,-3.69,1.117,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.100394,0.00369441,0.698291 kka2_1:2_L70P,kka2_1:2_70,Kka2,kka2_1:2,P00552,0.698372,NO,70,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.017,-4.164,3.147,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.295029,0.00411884,0.698372 beta-lactamase_156_A34P,beta-lactamase_156_34,TEM-1,beta-lactamase_156,P62593,0.698405,NO,34,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.059,-4.024,1.965,,,H,A,0.46,-0.54,3.614,,73.78,AHA,-1.74967,0.111618,0.00407913,0.698405 beta-lactamase_P224C,beta-lactamase_224,TEM-1,beta-lactamase,P62593,0.69842,NO,224,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.893,-5.08,4.187,5.179,0.383,,B,0.99,-0.3,0.383,,74.48,HOH,-1.26433,0.221079,0.00189564,0.69842 beta-lactamase_I45H,beta-lactamase_45,TEM-1,beta-lactamase,P62593,0.698437,NO,45,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-2.421,-3.408,0.987,5.31505,,E,B,1,-0.3,2.256,,77.62,HHA,-2.30267,0.221079,0.00452842,0.698437 beta-lactamase_N130G,beta-lactamase_130,TEM-1,beta-lactamase,P62593,0.698495,NO,130,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-0.798,-2.908,2.11,5.26686,0.069,H,A,1.08,-0.74,,,,APP,-0.980667,0.221079,0.000683376,0.698495 beta-lactamase_0_D174T,beta-lactamase_0_174,TEM-1,beta-lactamase_0,P62593,0.698684,NO,174,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.738,-3.421,2.683,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.0500837,0.00125633,0.698684 kka2_1:4_A137P,kka2_1:4_137,Kka2,kka2_1:4,P00552,0.698693,NO,137,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.156,-4.148,1.992,,0.029,H,A,0.46,0.34,2.227,,63.26,PHB,-2.559,0.168804,0.00515054,0.698693 beta-lactamase_0_D174S,beta-lactamase_0_174,TEM-1,beta-lactamase_0,P62593,0.6987,NO,174,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.738,-3.161,2.423,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.0500837,0.00125633,0.6987 beta-lactamase_2500_S80C,beta-lactamase_2500_80,TEM-1,beta-lactamase_2500,P62593,0.69889,NO,80,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.029,-4.922,2.893,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.361275,0.00565569,0.69889 PSD95pdz3_A375D,PSD95pdz3_375,PSD95pdz3,PSD95pdz3,P31016,0.698999,NO,375,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.307,-3.375,2.068,5.05512,,,,,13.888,,,,PHH,-1.43767,0.0758425,0.000356809,0.698999 PSD95pdz3_V386E,PSD95pdz3_386,PSD95pdz3,PSD95pdz3,P31016,0.69903,NO,386,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.465,-3.347,1.882,5.18836,,,,,17.5429,,,,PHP,-1.463,0.0758425,0.000184509,0.69903 beta-lactamase_0_T139F,beta-lactamase_0_139,TEM-1,beta-lactamase_0,P62593,0.699041,NO,139,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.901,-4.292,2.391,,0.216,H,A,0.22,0.39,0.421,,77.62,PPH,-2.04667,0.0500837,0.00441837,0.699041 beta-lactamase_2500_A183G,beta-lactamase_2500_183,TEM-1,beta-lactamase_2500,P62593,0.699098,NO,183,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.231,-3.077,1.846,,0.155,H,A,0.46,-0.91,12.189,,77.62,HHH,-1.53367,0.361275,0.00296631,0.699098 WW_domain_M179F,WW_domain_179,Yap65,WW_domain,P46937,0.69912,NO,179,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.541,-3.394,1.853,6.54704,,,,,,,,,AHH,-1.31367,0.153962,0.00400164,0.69912 kka2_1:2_C192F,kka2_1:2_192,Kka2,kka2_1:2,P00552,0.69922,NO,192,C,F,CF,Special,Hydrophobic,5.07,3.32051,-1.74949,205,121,165,44,108.5,189.9,81.4,-1.067,-4.014,2.947,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.295029,0.00485428,0.69922 kka2_1:4_E231D,kka2_1:4_231,Kka2,kka2_1:4,P00552,0.699221,NO,231,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.002,-2.09,0.088,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.168804,0.00732383,0.699221 kka2_1:1_G205V,kka2_1:1_205,Kka2,kka2_1:1,P00552,0.699415,NO,205,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.596,-3.782,3.186,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.520039,0.00221855,0.699415 kka2_1:1_A110V,kka2_1:1_110,Kka2,kka2_1:1,P00552,0.699484,NO,110,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.064,-2.939,0.875,,0.175,H,A,1.04,-1.19,11.755,,71.59,OHA,-1.91867,0.520039,0.00759851,0.699484 PSD95pdz3_G329T,PSD95pdz3_329,PSD95pdz3,PSD95pdz3,P31016,0.699485,NO,329,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.008,-3.328,2.32,4.7671,,,,,19.7075,,,,HOO,-1.16033,0.0758425,0.000974577,0.699485 beta-lactamase_I11Q,beta-lactamase_11,TEM-1,beta-lactamase,P62593,0.699833,NO,11,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.745,-4.18,2.435,,,,,,,3.135,,66.08,HHO,-1.79467,0.221079,0.00261325,0.699833 beta-lactamase_39_V78D,beta-lactamase_39_78,TEM-1,beta-lactamase_39,P62593,0.699901,NO,78,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.459,-4.082,2.623,,,H,A,0.44,-0.47,1.132,,63.64,HHH,-1.17833,0.0495842,0.00492501,0.699901 beta-lactamase_0_R81H,beta-lactamase_0_81,TEM-1,beta-lactamase_0,P62593,0.699978,NO,81,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.466,-4.464,2.998,,0.218,H,A,1.2,1.66,0.332,,50,PBH,-1.60667,0.0500837,0.00499763,0.699978 beta-lactamase_0_R81T,beta-lactamase_0_81,TEM-1,beta-lactamase_0,P62593,0.700058,NO,81,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.466,-3.547,2.081,,0.218,H,A,1.2,1.66,0.332,,50,PBH,-1.60667,0.0500837,0.00499763,0.700058 beta-lactamase_0_D207V,beta-lactamase_0_207,TEM-1,beta-lactamase_0,P62593,0.700072,NO,207,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.064,-3.771,1.707,,0.409,H,A,0.75,0.12,5.277,,77.62,HAH,-1.77033,0.0500837,0.00592942,0.700072 kka2_1:8_V198Y,kka2_1:8_198,Kka2,kka2_1:8,P00552,0.700098,NO,198,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.719,-4.264,2.545,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.100394,0.00835002,0.700098 kka2_1:8_V198Y,kka2_1:8_198,Kka2,kka2_1:8,P00552,0.700098,NO,198,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.719,-4.264,2.545,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.100394,0.00835002,0.700098 kka2_1:2_C131F,kka2_1:2_131,Kka2,kka2_1:2,P00552,0.700099,NO,131,C,F,CF,Special,Hydrophobic,5.07,3.32051,-1.74949,205,121,165,44,108.5,189.9,81.4,-0.831,-4.095,3.264,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.295029,0.00170814,0.700099 kka2_1:1_S251M,kka2_1:1_251,Kka2,kka2_1:1,P00552,0.700127,NO,251,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.636,-4.807,2.171,,0.712,H,A,0.27,-0.25,1.356,,71.59,APP,-2.09367,0.520039,0.0138916,0.700127 beta-lactamase_39_M184E,beta-lactamase_39_184,TEM-1,beta-lactamase_39,P62593,0.700201,NO,184,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.593,-3.708,2.115,,,H,A,0.55,-0.87,2.893,,62.94,HHH,-1.41,0.0495842,0.00356019,0.700201 beta-lactamase_0_V101D,beta-lactamase_0_101,TEM-1,beta-lactamase_0,P62593,0.700258,NO,101,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.295,-2.887,1.592,,0.342,,B,0.44,0,1.61,,73.08,HHA,-1.54367,0.0500837,0.00374492,0.700258 E1_Ubiquitin_H70Y,E1_Ubiquitin_70,Uba1,E1_Ubiquitin,P0CG63,0.700265,NO,70,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-1.36,,,,0.05,E,B,0.61,-0.97,,,93.18,HBH,-1.146,0.18783,0.00206914,0.700265 PSD95pdz3_G344P,PSD95pdz3_344,PSD95pdz3,PSD95pdz3,P31016,0.700276,NO,344,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.008,-3.561,2.553,4.83855,,,,,14.06,,,,HOO,-1.10767,0.0758425,0.00078498,0.700276 beta-lactamase_2500_F70W,beta-lactamase_2500_70,TEM-1,beta-lactamase_2500,P62593,0.700303,NO,70,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.169,-4.623,3.454,,,H,A,0.58,-1.34,1.918,,63.99,PHB,-0.980667,0.361275,0.00193499,0.700303 kka2_1:1_E235Y,kka2_1:1_235,Kka2,kka2_1:1,P00552,0.700307,NO,235,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.955,-4.43,2.475,,0.631,H,A,1.52,0.12,8.521,,65.53,OAH,-2.07267,0.520039,0.0102806,0.700307 beta-lactamase_0_V42M,beta-lactamase_0_42,TEM-1,beta-lactamase_0,P62593,0.700434,NO,42,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.564,-2.813,1.249,,0.017,E,B,0.44,-0.51,1.659,,63.99,BHO,-1.042,0.0500837,0.00404515,0.700434 kka2_1:1_N58S,kka2_1:1_58,Kka2,kka2_1:1,P00552,0.700441,NO,58,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-2.641,-1.901,-0.74,,0.131,S,A,0.61,0.72,30.755,30.755,71.59,HPA,-1.83033,0.520039,0.00793425,0.700441 beta-lactamase_2500_G243S,beta-lactamase_2500_243,TEM-1,beta-lactamase_2500,P62593,0.700632,NO,243,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.361275,0.00464034,0.700632 beta-lactamase_0_R59W,beta-lactamase_0_59,TEM-1,beta-lactamase_0,P62593,0.700681,NO,59,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.345,-5.421,4.076,,0.329,S,L,1.2,-0.09,2.919,,73.08,HBO,-2.24267,0.0500837,0.00318082,0.700681 beta-lactamase_0_I125G,beta-lactamase_0_125,TEM-1,beta-lactamase_0,P62593,0.700683,NO,125,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.441,-3.768,2.327,,,H,A,0.48,-0.7,1.874,,63.29,HHP,-1.248,0.0500837,0.00383964,0.700683 PSD95pdz3_V362K,PSD95pdz3_362,PSD95pdz3,PSD95pdz3,P31016,0.700762,NO,362,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.465,-3.364,1.899,4.99436,,,,,19.6443,,,,PHP,-1.46467,0.0758425,0.000538527,0.700762 beta-lactamase_2500_H24P,beta-lactamase_2500_24,TEM-1,beta-lactamase_2500,P62593,0.700835,NO,24,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-2.481,-3.827,1.346,,,,,,,0.467,,93.01,OBO,-2.0035,0.361275,0.00238894,0.700835 kka2_1:2_P194Q,kka2_1:2_194,Kka2,kka2_1:2,P00552,0.700863,NO,194,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.846,-3.927,3.081,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.295029,0.00314194,0.700863 kka2_1:8_I207M,kka2_1:8_207,Kka2,kka2_1:8,P00552,0.700916,NO,207,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.175,-4.117,2.942,,0.293,,B,1.52,-1.12,1.306,,56.06,HHA,-1.07733,0.100394,0.00611824,0.700916 kka2_1:8_I207M,kka2_1:8_207,Kka2,kka2_1:8,P00552,0.700916,NO,207,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.175,-4.117,2.942,,0.293,,B,1.52,-1.12,1.306,,56.06,HHA,-1.07733,0.100394,0.00611824,0.700916 kka2_1:1_N195K,kka2_1:1_195,Kka2,kka2_1:1,P00552,0.701003,NO,195,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-0.836,-3.304,2.468,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.520039,0.00276134,0.701003 gb1_G235V,gb1_235,gb1,gb1,P06654,0.701043,NO,235,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.419,-3.171,1.752,,,,,,,0.476,,11.83,POB,-1.86433,0.177985,0.00297491,0.701043 kka2_1:2_A229G,kka2_1:2_229,Kka2,kka2_1:2,P00552,0.701045,NO,229,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.739,-2.492,0.753,,0.32,H,A,0.46,-0.7,6.549,,63.64,HHA,-1.851,0.295029,0.00942138,0.701045 kka2_1:2_D23L,kka2_1:2_23,Kka2,kka2_1:2,P00552,0.701096,NO,23,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.459,-2.907,0.448,,0.695,E,B,0.75,-0.65,18.207,18.207,65.53,HAH,-1.94033,0.295029,0.007195,0.701096 PSD95pdz3_I327Y,PSD95pdz3_327,PSD95pdz3,PSD95pdz3,P31016,0.701148,NO,327,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.63,-3.619,1.989,5.7413,,,,,14.0388,,,,PHH,-1.50167,0.0758425,0.000998774,0.701148 kka2_1:8_Y218S,kka2_1:8_218,Kka2,kka2_1:8,P00552,0.701162,NO,218,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-1.438,-3.656,2.218,,0.122,H,A,1.25,-0.69,2.923,,56.06,BHP,-1.17533,0.100394,0.0126098,0.701162 kka2_1:8_Y218S,kka2_1:8_218,Kka2,kka2_1:8,P00552,0.701162,NO,218,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-1.438,-3.656,2.218,,0.122,H,A,1.25,-0.69,2.923,,56.06,BHP,-1.17533,0.100394,0.0126098,0.701162 kka2_1:1_A166L,kka2_1:1_166,Kka2,kka2_1:1,P00552,0.701172,NO,166,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.407,-3.58,1.173,,0.534,.,B,0.46,1.03,1.147,,71.59,HHO,-2.421,0.520039,0.00799912,0.701172 kka2_1:2_R211L,kka2_1:2_211,Kka2,kka2_1:2,P00552,0.701211,NO,211,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-0.899,-3.41,2.511,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.295029,0.00204888,0.701211 kka2_1:1_P194Q,kka2_1:1_194,Kka2,kka2_1:1,P00552,0.701241,NO,194,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.846,-3.927,3.081,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.520039,0.00314194,0.701241 kka2_1:1_R89H,kka2_1:1_89,Kka2,kka2_1:1,P00552,0.701268,NO,89,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.548,-2.435,0.887,,0.209,E,B,0.16,1.41,14.396,14.396,64.39,OBA,-1.89867,0.520039,0.00524373,0.701268 kka2_1:4_D183E,kka2_1:4_183,Kka2,kka2_1:4,P00552,0.701366,NO,183,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.204,-2.074,0.87,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.168804,0.00426304,0.701366 beta-lactamase_0_Y262L,beta-lactamase_0_262,TEM-1,beta-lactamase_0,P62593,0.701383,NO,262,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.0500837,0.00853516,0.701383 kka2_1:2_A34S,kka2_1:2_34,Kka2,kka2_1:2,P00552,0.701438,NO,34,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.928,-1.892,0.964,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.295029,0.00343484,0.701438 beta-lactamase_I11K,beta-lactamase_11,TEM-1,beta-lactamase,P62593,0.701464,NO,11,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.745,-3.738,1.993,,,,,,,3.135,,66.08,HHO,-1.79467,0.221079,0.00261325,0.701464 kka2_1:2_R145E,kka2_1:2_145,Kka2,kka2_1:2,P00552,0.701503,NO,145,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.804,-2.289,0.485,,0.346,H,A,1.2,1.23,7.961,,63.64,HBP,-1.88033,0.295029,0.00846663,0.701503 Ubiquitin_G35W,Ubiquitin_35,Uba1,Ubiquitin,P0CG48,0.701613,NO,35,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.171,-5.093,3.922,4.96213,0.713,,L,,0.2,,,,AOH,-1.314,0.205827,0.000648878,0.701613 Ubiquitin_K6L,Ubiquitin_6,Uba1,Ubiquitin,P0CG48,0.701613,NO,6,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.093,-3.408,2.315,4.84211,0.35,E,B,1.82,-0.62,1.502,,71.82,HBP,-1.36133,0.205827,0.000784795,0.701613 Ubiquitin_Q49K,Ubiquitin_49,Uba1,Ubiquitin,P0CG48,0.701613,NO,49,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-1.941,-2.555,0.614,5.05026,0.403,E,B,,-0.59,,,,BPH,-1.49467,0.205827,0.000613067,0.701613 Ubiquitin_T66R,Ubiquitin_66,Uba1,Ubiquitin,P0CG48,0.701613,NO,66,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.58,-3.021,1.441,5.02702,0.46,E,B,0.8,-0.81,28.36,28.36,39.71,PPH,-1.51667,0.205827,0.000598414,0.701613 Ubiquitin_V26F,Ubiquitin_26,Uba1,Ubiquitin,P0CG48,0.701613,NO,26,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.321,-3.833,2.512,4.78447,,H,A,,-0.97,,,,PHB,-1.445,0.205827,0.000980269,0.701613 kka2_1:1_Q42T,kka2_1:1_42,Kka2,kka2_1:1,P00552,0.701686,NO,42,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.907,-2.915,0.008,,1.044,T,B,0.4,-0.8,2.792,,71.59,HPO,-2.12433,0.520039,0.00679212,0.701686 kka2_1:2_T51H,kka2_1:2_51,Kka2,kka2_1:2,P00552,0.701703,NO,51,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.199,-2.994,0.795,,0.05,E,B,0.22,-0.05,13.165,13.165,63.64,BPA,-1.76767,0.295029,0.00628861,0.701703 kka2_1:2_G201D,kka2_1:2_201,Kka2,kka2_1:2,P00552,0.701761,NO,201,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.56,-2.294,0.734,,0.149,T,l,0.29,-0.57,16.092,16.092,52.65,POB,-1.92233,0.295029,0.00820117,0.701761 beta-lactamase_G141I,beta-lactamase_141,TEM-1,beta-lactamase,P62593,0.701817,NO,141,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.828,-4.236,3.408,5.03155,0.575,T,l,0.76,-0.28,0.198,,64.69,HOO,-1.08933,0.221079,0.0012419,0.701817 kka2_1:2_L102M,kka2_1:2_102,Kka2,kka2_1:2,P00552,0.701854,NO,102,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.804,-2.818,2.014,,,T,A,1.59,-1.17,4.258,,42.42,AHH,-1.398,0.295029,0.00201332,0.701854 kka2_1:8_L241Q,kka2_1:8_241,Kka2,kka2_1:8,P00552,0.701855,NO,241,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.158,-4.313,3.155,,0.08,H,A,1.59,-0.82,1.136,,63.26,HHH,-1.58533,0.100394,0.0117299,0.701855 kka2_1:8_L241Q,kka2_1:8_241,Kka2,kka2_1:8,P00552,0.701855,NO,241,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.158,-4.313,3.155,,0.08,H,A,1.59,-0.82,1.136,,63.26,HHH,-1.58533,0.100394,0.0117299,0.701855 kka2_1:1_M178W,kka2_1:1_178,Kka2,kka2_1:1,P00552,0.701874,NO,178,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-3.206,-5.507,2.301,,0.554,.,b,0.55,0.68,3.152,,71.59,BHO,-2.154,0.520039,0.00717253,0.701874 kka2_1:4_I115D,kka2_1:4_115,Kka2,kka2_1:4,P00552,0.701879,NO,115,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.606,-4.12,2.514,,0.105,H,A,1.52,-1.18,9.996,9.996,65.53,PHH,-2.205,0.168804,0.00836567,0.701879 kka2_1:2_G213C,kka2_1:2_213,Kka2,kka2_1:2,P00552,0.701926,NO,213,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.596,-5.115,4.519,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.295029,0.00187654,0.701926 kka2_1:2_V198H,kka2_1:2_198,Kka2,kka2_1:2,P00552,0.701928,NO,198,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.719,-4.876,3.157,,0.05,E,B,1.48,-0.95,1.074,,56.06,HHA,-1.88667,0.295029,0.00835002,0.701928 beta-lactamase_V258G,beta-lactamase_258,TEM-1,beta-lactamase,P62593,0.702003,NO,258,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.975,-3.39,1.415,5.16083,,E,B,1.64,-1.02,2.124,,67.83,HHH,-1.67667,0.221079,0.007931,0.702003 E1_Ubiquitin_R72S,E1_Ubiquitin_72,Uba1,E1_Ubiquitin,P0CG63,0.702034,NO,72,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.184,-3.203,2.019,,0.077,,B,0.16,-0.1,,,,HBH,-1.08733,0.18783,0.00129853,0.702034 kka2_1:4_L184Y,kka2_1:4_184,Kka2,kka2_1:4,P00552,0.70204,NO,184,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.496,-4.144,2.648,,0.489,E,B,1.59,-0.06,4.495,,63.26,AHH,-1.24833,0.168804,0.00518742,0.70204 kka2_1:2_F37S,kka2_1:2_37,Kka2,kka2_1:2,P00552,0.702047,NO,37,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.427,-2.956,1.529,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.295029,0.00586193,0.702047 kka2_1:2_P132A,kka2_1:2_132,Kka2,kka2_1:2,P00552,0.702049,NO,132,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.775,-3.073,2.298,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.295029,0.0018489,0.702049 beta-lactamase_V214E,beta-lactamase_214,TEM-1,beta-lactamase,P62593,0.702059,NO,214,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.299,-3.704,2.405,5.74008,0.375,S,A,1.19,-0.44,1.899,,74.48,BHH,-1.53733,0.221079,0.00628442,0.702059 gb1_A250K,gb1_250,gb1,gb1,P06654,0.702071,NO,250,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.713,-2.948,1.235,,,,,,,3.465,,45.54,HHP,-1.74867,0.177985,0.00332003,0.702071 gb1_N263W,gb1_263,gb1,gb1,P06654,0.702071,NO,263,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-1.162,-5.324,4.162,,,,,,,,,,APO,-2.04233,0.177985,0.0035297,0.702071 kka2_1:8_R226K,kka2_1:8_226,Kka2,kka2_1:8,P00552,0.70214,NO,226,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.392,-3.285,1.893,,0.222,H,A,0.16,-0.71,3.818,,56.06,PBA,-1.84767,0.100394,0.0108032,0.70214 kka2_1:8_R226K,kka2_1:8_226,Kka2,kka2_1:8,P00552,0.70214,NO,226,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.392,-3.285,1.893,,0.222,H,A,0.16,-0.71,3.818,,56.06,PBA,-1.84767,0.100394,0.0108032,0.70214 beta-lactamase_N168L,beta-lactamase_168,TEM-1,beta-lactamase,P62593,0.70216,NO,168,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-1.029,-3.516,2.487,5.42128,0.113,G,A,0.09,-0.4,1.211,,44.41,HPA,-1.13233,0.221079,0.00288667,0.70216 kka2_1:2_G233C,kka2_1:2_233,Kka2,kka2_1:2,P00552,0.70217,NO,233,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.748,-5.16,4.412,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.295029,0.00232366,0.70217 beta-lactamase_0_L197C,beta-lactamase_0_197,TEM-1,beta-lactamase_0,P62593,0.702178,NO,197,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.853,-4.635,3.782,,0.007,S,B,0.55,0.33,1.087,,60.14,HHP,-1.833,0.0500837,0.00144602,0.702178 beta-lactamase_0_H151M,beta-lactamase_0_151,TEM-1,beta-lactamase_0,P62593,0.702224,NO,151,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-2.96,-4.581,1.621,,0.594,H,A,0.17,0.1,9.375,,77.62,HBP,-2.34767,0.0500837,0.00216946,0.702224 beta-lactamase_N168H,beta-lactamase_168,TEM-1,beta-lactamase,P62593,0.702225,NO,168,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-1.029,-4.17,3.141,5.42128,0.113,G,A,0.09,-0.4,1.211,,44.41,HPA,-1.13233,0.221079,0.00288667,0.702225 kka2_1:1_R202L,kka2_1:1_202,Kka2,kka2_1:1,P00552,0.702377,NO,202,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.761,-3.611,1.85,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.520039,0.00696498,0.702377 kka2_1:2_Q163P,kka2_1:2_163,Kka2,kka2_1:2,P00552,0.702398,NO,163,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.162,-4.062,1.9,,0.58,T,B,0.64,1.85,3.888,,64.02,BPO,-1.78333,0.295029,0.00719507,0.702398 kka2_1:2_S104N,kka2_1:2_104,Kka2,kka2_1:2,P00552,0.702416,NO,104,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.436,-2.903,1.467,,0.536,T,A,0.27,-1.11,5.49,,63.64,HPP,-1.91433,0.295029,0.00555207,0.702416 beta-lactamase_P20A,beta-lactamase_20,TEM-1,beta-lactamase,P62593,0.702444,NO,20,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.74,-1.516,-0.224,,,,,,,0.368,,67.83,HOH,-1.765,0.221079,0.00235322,0.702444 kka2_1:8_L81P,kka2_1:8_81,Kka2,kka2_1:8,P00552,0.702465,NO,81,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.427,-4.19,2.763,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.100394,0.00805839,0.702465 kka2_1:8_L81P,kka2_1:8_81,Kka2,kka2_1:8,P00552,0.702465,NO,81,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.427,-4.19,2.763,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.100394,0.00805839,0.702465 kka2_1:2_E182T,kka2_1:2_182,Kka2,kka2_1:2,P00552,0.702495,NO,182,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.516,-2.525,1.009,,0.326,,B,1.52,0.75,14.547,14.547,65.53,OAA,-1.806,0.295029,0.00641548,0.702495 kka2_1:2_D62G,kka2_1:2_62,Kka2,kka2_1:2,P00552,0.70254,NO,62,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.591,-1.697,0.106,,0.262,H,A,0.75,0.08,10.048,10.048,64.39,PAA,-1.77833,0.295029,0.00744243,0.70254 kka2_1:2_A65G,kka2_1:2_65,Kka2,kka2_1:2,P00552,0.702565,NO,65,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.744,-2.917,1.173,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.295029,0.00709258,0.702565 PSD95pdz3_E373P,PSD95pdz3_373,PSD95pdz3,PSD95pdz3,P31016,0.7026,NO,373,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.404,-3.336,1.932,5.79743,,,,,27.9833,,,,BAP,-1.57667,0.0758425,0.000387698,0.7026 kka2_1:2_G164K,kka2_1:2_164,Kka2,kka2_1:2,P00552,0.702691,NO,164,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.869,-3.652,2.783,,0.862,T,l,0.75,1.45,1.539,,64.39,POH,-1.828,0.295029,0.00442091,0.702691 beta-lactamase_2500_E87A,beta-lactamase_2500_87,TEM-1,beta-lactamase_2500,P62593,0.702745,NO,87,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.421,-3.209,1.788,,0.048,,B,1.04,0.92,17.923,17.923,64.69,PAP,-1.969,0.361275,0.00337888,0.702745 beta-lactamase_S264R,beta-lactamase_264,TEM-1,beta-lactamase,P62593,0.702753,NO,264,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.985,-3.074,1.089,4.67475,0.04,,B,0.25,0.29,34.251,34.251,73.78,OPP,-2.19867,0.221079,0.0119399,0.702753 kka2_1:1_G181V,kka2_1:1_181,Kka2,kka2_1:1,P00552,0.7028,NO,181,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-2.698,-2.527,-0.171,,0.379,S,B,0.75,0.78,15.356,15.356,71.59,AOA,-2.21,0.520039,0.00728319,0.7028 kka2_1:8_A215E,kka2_1:8_215,Kka2,kka2_1:8,P00552,0.702872,NO,215,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.968,-3.495,2.527,,0.039,E,B,1.04,-0.59,2.77,,50.38,HHA,-1.00467,0.100394,0.00529129,0.702872 kka2_1:8_A215E,kka2_1:8_215,Kka2,kka2_1:8,P00552,0.702872,NO,215,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.968,-3.495,2.527,,0.039,E,B,1.04,-0.59,2.77,,50.38,HHA,-1.00467,0.100394,0.00529129,0.702872 beta-lactamase_0_I229G,beta-lactamase_0_229,TEM-1,beta-lactamase_0,P62593,0.702928,NO,229,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.267,-3.782,2.515,,0.083,E,B,0.48,-0.76,1.69,,50,HHH,-1.58767,0.0500837,0.00477249,0.702928 kka2_1:1_A41T,kka2_1:1_41,Kka2,kka2_1:1,P00552,0.702955,NO,41,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.879,-3.68,1.801,,0.184,.,B,0.46,-0.96,18.207,18.207,64.39,PHP,-2.477,0.520039,0.00543332,0.702955 beta-lactamase_2500_A170L,beta-lactamase_2500_170,TEM-1,beta-lactamase_2500,P62593,0.703039,NO,170,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.237,-3.289,2.052,,0.126,,L,0.46,-0.35,2.427,,64.69,AHH,-1.63267,0.361275,0.00431903,0.703039 beta-lactamase_0_W227G,beta-lactamase_0_227,TEM-1,beta-lactamase_0,P62593,0.70304,NO,227,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-0.982,-2.451,1.469,,0.272,,B,0.47,-0.29,3.782,,74.48,OHH,-1.595,0.0500837,0.00226019,0.70304 beta-lactamase_0_G265I,beta-lactamase_0_265,TEM-1,beta-lactamase_0,P62593,0.703138,NO,265,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.0500837,0.00811926,0.703138 kka2_1:4_P128S,kka2_1:4_128,Kka2,kka2_1:4,P00552,0.70317,NO,128,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.922,-3.672,1.75,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.168804,0.00774689,0.70317 beta-lactamase_V82D,beta-lactamase_82,TEM-1,beta-lactamase,P62593,0.703211,NO,82,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.325,-3.879,2.554,5.27777,0.267,H,A,0.96,0.08,1.379,,93.01,BHA,-1.28567,0.221079,0.00397046,0.703211 kka2_1:4_D62L,kka2_1:4_62,Kka2,kka2_1:4,P00552,0.703218,NO,62,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.591,-3.008,1.417,,0.262,H,A,0.29,0.08,14.756,14.756,64.39,PAA,-1.77833,0.168804,0.00744243,0.703218 beta-lactamase_0_L197I,beta-lactamase_0_197,TEM-1,beta-lactamase_0,P62593,0.703235,NO,197,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.853,-2.968,2.115,,0.007,S,B,0.55,0.33,1.087,,60.14,HHP,-1.833,0.0500837,0.00144602,0.703235 kka2_1:4_E63A,kka2_1:4_63,Kka2,kka2_1:4,P00552,0.703244,NO,63,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-0.762,-3.106,2.344,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.168804,0.00118399,0.703244 kka2_1:1_L165A,kka2_1:1_165,Kka2,kka2_1:1,P00552,0.703327,NO,165,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-2.453,-2.69,0.237,,0.299,,B,1.59,1.12,2.47,,64.39,OHH,-1.90967,0.520039,0.00801161,0.703327 beta-lactamase_2500_G265C,beta-lactamase_2500_265,TEM-1,beta-lactamase_2500,P62593,0.703352,NO,265,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.361275,0.00811926,0.703352 kka2_1:1_D261Y,kka2_1:1_261,Kka2,kka2_1:1,P00552,0.703379,NO,261,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.708,-4.416,3.708,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.520039,0.0224846,0.703379 PSD95pdz3_I316K,PSD95pdz3_316,PSD95pdz3,PSD95pdz3,P31016,0.703392,NO,316,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.63,-3.589,1.959,5.46166,,,,,19.005,,,,HHB,-1.62733,0.0758425,0.00112762,0.703392 kka2_1:4_L260F,kka2_1:4_260,Kka2,kka2_1:4,P00552,0.70346,NO,260,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.741,-3.645,2.904,,0.022,H,A,0.55,-0.52,,,,HHA,-0.845667,0.168804,0.0233782,0.70346 kka2_1:8_D159H,kka2_1:8_159,Kka2,kka2_1:8,P00552,0.703561,NO,159,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.82,-4.547,3.727,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.100394,0.0030485,0.703561 kka2_1:8_D159H,kka2_1:8_159,Kka2,kka2_1:8,P00552,0.703561,NO,159,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.82,-4.547,3.727,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.100394,0.0030485,0.703561 beta-lactamase_156_T27E,beta-lactamase_156_27,TEM-1,beta-lactamase_156,P62593,0.703562,NO,27,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.905,-2.714,0.809,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.111618,0.00306559,0.703562 beta-lactamase_0_S221E,beta-lactamase_0_221,TEM-1,beta-lactamase_0,P62593,0.703565,NO,221,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.754,-3.442,1.688,,0.624,H,A,0.27,-0.2,2.914,,74.48,BPH,-1.59967,0.0500837,0.0046094,0.703565 kka2_1:1_S204I,kka2_1:1_204,Kka2,kka2_1:1,P00552,0.703575,NO,204,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.353,-3.845,2.492,,0.144,E,A,0.27,-1.2,3.022,,65.53,HPO,-0.953333,0.520039,0.00881794,0.703575 kka2_1:2_P109Q,kka2_1:2_109,Kka2,kka2_1:2,P00552,0.703588,NO,109,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.412,-3.143,1.731,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.295029,0.0070929,0.703588 kka2_1:4_F48L,kka2_1:4_48,Kka2,kka2_1:4,P00552,0.703601,NO,48,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.453,-2.543,1.09,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.168804,0.00475422,0.703601 kka2_1:1_S105R,kka2_1:1_105,Kka2,kka2_1:1,P00552,0.703625,NO,105,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.945,-3.214,1.269,,0.056,S,B,0.27,-1.04,3.442,,65.53,PPB,-2.17033,0.520039,0.00847233,0.703625 beta-lactamase_2500_L111E,beta-lactamase_2500_111,TEM-1,beta-lactamase_2500,P62593,0.703628,NO,111,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.76,-3.773,2.013,,0.328,T,A,0.55,0.93,1.966,,64.34,BHP,-1.884,0.361275,0.00480671,0.703628 beta-lactamase_2500_R63I,beta-lactamase_2500_63,TEM-1,beta-lactamase_2500,P62593,0.703639,NO,63,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-0.943,-3.824,2.881,,0.218,,B,1.2,-0.31,0.929,,44.06,ABH,-0.992333,0.361275,0.00126938,0.703639 beta-lactamase_156_G142Y,beta-lactamase_156_142,TEM-1,beta-lactamase_156,P62593,0.70364,NO,142,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.707,-4.385,3.678,,0.034,,p,0.29,-0.64,0.325,,64.69,OOO,-0.834,0.111618,0.00060149,0.70364 beta-lactamase_D231S,beta-lactamase_231,TEM-1,beta-lactamase,P62593,0.703664,NO,231,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.816,-3.186,2.37,5.06651,,E,B,1.22,-1.06,0.319,,65.38,HAB,-0.994,0.221079,0.00107395,0.703664 beta-lactamase_A215K,beta-lactamase_215,TEM-1,beta-lactamase,P62593,0.703749,NO,215,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.503,-3.575,2.072,4.82164,,,a,0.75,-0.93,3.583,,74.48,HHO,-1.42633,0.221079,0.00544007,0.703749 kka2_1:2_R140G,kka2_1:2_140,Kka2,kka2_1:2,P00552,0.703786,NO,140,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.351,-2.695,1.344,,0.12,H,A,1.2,0.2,0.352,,53.03,BBH,-1.885,0.295029,0.00430167,0.703786 beta-lactamase_A215N,beta-lactamase_215,TEM-1,beta-lactamase,P62593,0.703863,NO,215,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.503,-3.679,2.176,4.82164,,,a,0.75,-0.93,3.583,,74.48,HHO,-1.42633,0.221079,0.00544007,0.703863 kka2_1:1_R38L,kka2_1:1_38,Kka2,kka2_1:1,P00552,0.703894,NO,38,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.207,-1.87,0.663,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.520039,0.00372499,0.703894 kka2_1:1_D52Y,kka2_1:1_52,Kka2,kka2_1:1,P00552,0.70392,NO,52,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.271,-4.235,1.964,,0.22,E,B,0.75,0.8,2.64,,71.59,PAH,-2.38367,0.520039,0.00175694,0.70392 kka2_1:4_W15V,kka2_1:4_15,Kka2,kka2_1:4,P00552,0.703927,NO,15,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-1.392,-3.309,1.917,,0.01,G,A,0.47,0.15,0.943,,52.27,HHH,-2.10533,0.168804,0.00585505,0.703927 beta-lactamase_L197T,beta-lactamase_197,TEM-1,beta-lactamase,P62593,0.703929,NO,197,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.853,-3.419,2.566,5.19172,0.007,S,B,1.3,0.33,1.756,,60.14,HHP,-1.833,0.221079,0.00144602,0.703929 kka2_1:1_L102M,kka2_1:1_102,Kka2,kka2_1:1,P00552,0.703938,NO,102,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.804,-2.818,2.014,,,T,A,0.55,-1.17,4.258,,42.42,AHH,-1.398,0.520039,0.00201332,0.703938 beta-lactamase_T131Y,beta-lactamase_131,TEM-1,beta-lactamase,P62593,0.704022,NO,131,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.328,-4.285,2.957,5.0548,,H,A,0.53,-0.69,3.306,,67.48,PPH,-1.00867,0.221079,0.00345886,0.704022 kka2_1:4_D90V,kka2_1:4_90,Kka2,kka2_1:4,P00552,0.70418,NO,90,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.459,-3.794,1.335,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.168804,0.00583842,0.70418 kka2_1:8_E3A,kka2_1:8_3,Kka2,kka2_1:8,P00552,0.704209,NO,3,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.199,-2.95,0.751,,,,,,,7.22,,92.05,HAP,-2.11567,0.100394,0.00267607,0.704209 kka2_1:8_E3A,kka2_1:8_3,Kka2,kka2_1:8,P00552,0.704209,NO,3,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.199,-2.95,0.751,,,,,,,7.22,,92.05,HAP,-2.11567,0.100394,0.00267607,0.704209 beta-lactamase_39_G243V,beta-lactamase_39_243,TEM-1,beta-lactamase_39,P62593,0.704214,NO,243,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.0495842,0.00464034,0.704214 kka2_1:4_E169W,kka2_1:4_169,Kka2,kka2_1:4,P00552,0.704229,NO,169,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.996,-5.529,3.533,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.168804,0.00730086,0.704229 beta-lactamase_0_L89G,beta-lactamase_0_89,TEM-1,beta-lactamase_0,P62593,0.70424,NO,89,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.096,-3.653,2.557,,0.168,T,A,0.55,0.63,2.373,,64.34,PHO,-1.75767,0.0500837,0.00207068,0.70424 kka2_1:2_D156C,kka2_1:2_156,Kka2,kka2_1:2,P00552,0.704274,NO,156,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.696,-3.452,1.756,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.295029,0.00926998,0.704274 beta-lactamase_2500_R273G,beta-lactamase_2500_273,TEM-1,beta-lactamase_2500,P62593,0.704286,NO,273,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.314,-2.465,0.151,,0.564,H,A,1.2,1.57,19.943,19.943,73.78,ABP,-1.841,0.361275,0.0077952,0.704286 beta-lactamase_2500_L167A,beta-lactamase_2500_167,TEM-1,beta-lactamase_2500,P62593,0.704288,NO,167,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.138,-3.097,1.959,,0.015,G,A,0.55,-0.63,7.813,,64.69,AHP,-1.30767,0.361275,0.00303566,0.704288 Pab1_I157N,Pab1_157,Pab1,Pab1,P04147,0.70436,NO,157,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.623,-4.011,2.388,,,,,,,1.439,,79.72,BHH,-1.28667,0.175299,0.0018103,0.70436 beta-lactamase_0_E195L,beta-lactamase_0_195,TEM-1,beta-lactamase_0,P62593,0.704361,NO,195,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.186,-3.741,1.555,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.0500837,0.00496565,0.704361 beta-lactamase_625_G141V,beta-lactamase_625_141,TEM-1,beta-lactamase_625,P62593,0.70437,NO,141,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.828,-3.79,2.962,,0.575,T,l,0.29,-0.28,0.198,,64.69,HOO,-1.08933,0.213352,0.0012419,0.70437 kka2_1:1_A56S,kka2_1:1_56,Kka2,kka2_1:1,P00552,0.70438,NO,56,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.083,-2.605,0.522,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.520039,0.00717715,0.70438 beta-lactamase_0_L284Q,beta-lactamase_0_284,TEM-1,beta-lactamase_0,P62593,0.704382,NO,284,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.981,,,,0.848,H,A,2.89,0.67,4.544,,77.62,PHH,-1.82133,0.0500837,0.0686156,0.704382 kka2_1:4_I141S,kka2_1:4_141,Kka2,kka2_1:4,P00552,0.704421,NO,141,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.495,-3.763,2.268,,0.068,H,A,0.48,-0.01,2.144,,92.05,BHA,-1.689,0.168804,0.00744745,0.704421 beta-lactamase_0_Q97N,beta-lactamase_0_97,TEM-1,beta-lactamase_0,P62593,0.704422,NO,97,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.072,-3.773,1.701,,0.823,G,A,0.64,2.42,16.954,16.954,77.62,PPP,-2.43833,0.0500837,0.0045116,0.704422 beta-lactamase_156_I285P,beta-lactamase_156_285,TEM-1,beta-lactamase_156,P62593,0.70445,NO,285,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.111618,0.101555,0.70445 kka2_1:1_W236R,kka2_1:1_236,Kka2,kka2_1:1,P00552,0.704664,NO,236,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-1.363,-4.21,2.847,,0.303,H,A,1.51,-0.76,12.263,12.263,48.48,AHH,-1.81267,0.520039,0.0088796,0.704664 kka2_1:8_V198F,kka2_1:8_198,Kka2,kka2_1:8,P00552,0.704694,NO,198,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.719,-4.163,2.444,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.100394,0.00835002,0.704694 kka2_1:8_V198F,kka2_1:8_198,Kka2,kka2_1:8,P00552,0.704694,NO,198,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.719,-4.163,2.444,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.100394,0.00835002,0.704694 kka2_1:1_G201V,kka2_1:1_201,Kka2,kka2_1:1,P00552,0.704714,NO,201,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.56,-3.892,2.332,,0.149,T,l,0.29,-0.57,16.092,16.092,52.65,POB,-1.92233,0.520039,0.00820117,0.704714 kka2_1:1_F37S,kka2_1:1_37,Kka2,kka2_1:1,P00552,0.704723,NO,37,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.427,-2.956,1.529,,0.219,E,B,0.58,-0.25,18.64,18.64,64.39,HHB,-1.17733,0.520039,0.00586193,0.704723 beta-lactamase_2500_R92P,beta-lactamase_2500_92,TEM-1,beta-lactamase_2500,P62593,0.704808,NO,92,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.718,-3.033,1.315,,0.479,E,B,1.2,1.36,3.069,,65.38,BBH,-1.50367,0.361275,0.00429626,0.704808 beta-lactamase_2500_L55T,beta-lactamase_2500_55,TEM-1,beta-lactamase_2500,P62593,0.704819,NO,55,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.86,-3.617,1.757,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.361275,0.00403741,0.704819 kka2_1:1_S40T,kka2_1:1_40,Kka2,kka2_1:1,P00552,0.704836,NO,40,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.645,-2.259,-0.386,,0.32,E,B,0.27,-0.9,25.997,25.997,71.59,HPH,-1.91567,0.520039,0.00693477,0.704836 WW_domain_P174T,WW_domain_174,Yap65,WW_domain,P46937,0.704855,NO,174,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.035,-3.198,2.163,,,,,,,,,,HOH,-1.261,0.153962,0.000711366,0.704855 kka2_1:1_F37Y,kka2_1:1_37,Kka2,kka2_1:1,P00552,0.70486,NO,37,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.427,-2.628,1.201,,0.219,E,B,0.58,-0.25,18.64,18.64,64.39,HHB,-1.17733,0.520039,0.00586193,0.70486 beta-lactamase_39_I229D,beta-lactamase_39_229,TEM-1,beta-lactamase_39,P62593,0.704876,NO,229,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.267,-3.973,2.706,,0.083,E,B,0.48,-0.76,1.114,,50,HHH,-1.58767,0.0495842,0.00477249,0.704876 beta-lactamase_0_A215M,beta-lactamase_0_215,TEM-1,beta-lactamase_0,P62593,0.70497,NO,215,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.503,-4.708,3.205,,,,a,0.46,-0.93,0.494,,74.48,HHO,-1.42633,0.0500837,0.00544007,0.70497 kka2_1:8_R66A,kka2_1:8_66,Kka2,kka2_1:8,P00552,0.704977,NO,66,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-0.922,-3.14,2.218,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.100394,0.00161025,0.704977 kka2_1:8_R66A,kka2_1:8_66,Kka2,kka2_1:8,P00552,0.704977,NO,66,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-0.922,-3.14,2.218,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.100394,0.00161025,0.704977 kka2_1:4_G88V,kka2_1:4_88,Kka2,kka2_1:4,P00552,0.705006,NO,88,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.689,-2.928,1.239,,0.54,S,l,0.29,1.51,7.899,,65.53,HOB,-1.718,0.168804,0.00685559,0.705006 beta-lactamase_0_E169Q,beta-lactamase_0_169,TEM-1,beta-lactamase_0,P62593,0.705038,NO,169,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.23,-2.523,1.293,,0.337,,A,1.04,1,3.516,,73.08,PAH,-1.16533,0.0500837,0.00400994,0.705038 beta-lactamase_0_L73W,beta-lactamase_0_73,TEM-1,beta-lactamase_0,P62593,0.705103,NO,73,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.507,-5.171,3.664,,,H,A,0.55,-0.64,0.877,,67.83,HHH,-1.487,0.0500837,0.00488983,0.705103 gb1_L238W,gb1_238,gb1,gb1,P06654,0.705117,NO,238,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-2.98,-4.633,1.653,,,,,,,0.504,,45.54,PHB,-2.58633,0.177985,0.00205885,0.705117 kka2_1:8_F256S,kka2_1:8_256,Kka2,kka2_1:8,P00552,0.705138,NO,256,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.49,-3.766,2.276,,,H,A,1.62,-0.78,1.713,,53.03,HHH,-1.423,0.100394,0.0132841,0.705138 kka2_1:8_F256S,kka2_1:8_256,Kka2,kka2_1:8,P00552,0.705138,NO,256,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.49,-3.766,2.276,,,H,A,1.62,-0.78,1.713,,53.03,HHH,-1.423,0.100394,0.0132841,0.705138 kka2_1:4_G74W,kka2_1:4_74,Kka2,kka2_1:4,P00552,0.705207,NO,74,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.18,-5.433,4.253,,0.621,T,l,0.75,0.2,1.032,,64.39,POH,-1.91667,0.168804,0.00587035,0.705207 kka2_1:1_Q100H,kka2_1:1_100,Kka2,kka2_1:1,P00552,0.705243,NO,100,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.77,-2.906,0.136,,0.646,E,B,0.4,-0.79,15.116,15.116,71.59,OPA,-1.46467,0.520039,0.0066405,0.705243 kka2_1:1_D261G,kka2_1:1_261,Kka2,kka2_1:1,P00552,0.705384,NO,261,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.708,-3.161,2.453,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.520039,0.0224846,0.705384 beta-lactamase_Q274P,beta-lactamase_274,TEM-1,beta-lactamase,P62593,0.705418,NO,274,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.082,-3.87,1.788,5.6671,0.066,H,A,0.11,-0.27,2.354,,64.69,BPH,-1.931,0.221079,0.0110418,0.705418 beta-lactamase_0_S96Y,beta-lactamase_0_96,TEM-1,beta-lactamase_0,P62593,0.70545,NO,96,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.27,-4.345,2.075,,0.368,,b,0.27,0.39,2.516,,73.78,HPP,-2.019,0.0500837,0.00551835,0.70545 beta-lactamase_0_P65Q,beta-lactamase_0_65,TEM-1,beta-lactamase_0,P62593,0.705526,NO,65,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.894,-3.954,3.06,,0.098,E,B,0.52,-0.62,0.663,,40.56,HOH,-1.03233,0.0500837,0.00152776,0.705526 beta-lactamase_P165W,beta-lactamase_165,TEM-1,beta-lactamase,P62593,0.705552,NO,165,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.373,-5.352,3.979,5.33889,0.203,T,A,0.99,-0.31,0.414,,73.78,AOA,-1.359,0.221079,0.00549538,0.705552 E1_Ubiquitin_H70S,E1_Ubiquitin_70,Uba1,E1_Ubiquitin,P0CG63,0.70557,NO,70,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-1.36,,,,0.05,E,B,0.61,-0.97,,,93.18,HBH,-1.146,0.18783,0.00206914,0.70557 beta-lactamase_D99P,beta-lactamase_99,TEM-1,beta-lactamase,P62593,0.705603,NO,99,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.191,-3.8,2.609,5.66081,0.402,G,A,0.23,0.36,1.318,,64.69,PAH,-1.794,0.221079,0.00305446,0.705603 beta-lactamase_2500_V106H,beta-lactamase_2500_106,TEM-1,beta-lactamase_2500,P62593,0.70563,NO,106,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.218,-4.937,3.719,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.361275,0.00304168,0.70563 beta-lactamase_H110I,beta-lactamase_110,TEM-1,beta-lactamase,P62593,0.705714,NO,110,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-1.706,-4.048,2.342,5.52635,0.341,G,a,0.35,1.08,31.31,31.31,64.69,BBH,-1.73333,0.221079,0.00441499,0.705714 kka2_1:1_F171V,kka2_1:1_171,Kka2,kka2_1:1,P00552,0.705738,NO,171,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.326,-3.284,1.958,,0.154,H,A,1.62,-0.1,13.679,13.679,63.64,HHH,-1.45433,0.520039,0.00821426,0.705738 kka2_1:2_R226G,kka2_1:2_226,Kka2,kka2_1:2,P00552,0.705752,NO,226,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.392,-2.496,1.104,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.295029,0.0108032,0.705752 kka2_1:8_H124D,kka2_1:8_124,Kka2,kka2_1:8,P00552,0.705823,NO,124,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-0.84,-3.497,2.657,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.100394,0.00211296,0.705823 kka2_1:8_H124D,kka2_1:8_124,Kka2,kka2_1:8,P00552,0.705823,NO,124,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-0.84,-3.497,2.657,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.100394,0.00211296,0.705823 kka2_1:8_L39H,kka2_1:8_39,Kka2,kka2_1:8,P00552,0.705863,NO,39,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.223,-4.999,3.776,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.100394,0.00493618,0.705863 kka2_1:8_L39H,kka2_1:8_39,Kka2,kka2_1:8,P00552,0.705863,NO,39,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.223,-4.999,3.776,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.100394,0.00493618,0.705863 beta-lactamase_625_K30G,beta-lactamase_625_30,TEM-1,beta-lactamase_625,P62593,0.705872,NO,30,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-2.307,-3.406,1.099,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.213352,0.00448593,0.705872 beta-lactamase_156_I277W,beta-lactamase_156_277,TEM-1,beta-lactamase_156,P62593,0.705999,NO,277,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.111618,0.0169305,0.705999 beta-lactamase_P249F,beta-lactamase_249,TEM-1,beta-lactamase,P62593,0.706034,NO,249,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.312,-4.382,3.07,5.10655,0.256,S,B,0.99,0.04,0.479,,72.73,OOA,-1.81367,0.221079,0.00220169,0.706034 beta-lactamase_625_N152P,beta-lactamase_625_152,TEM-1,beta-lactamase_625,P62593,0.706043,NO,152,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-2.757,-3.97,1.213,,0.863,H,A,0.61,0.92,2.061,,77.62,BPH,-2.97,0.213352,0.00471429,0.706043 kka2_1:1_A168M,kka2_1:1_168,Kka2,kka2_1:1,P00552,0.706134,NO,168,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.989,-4.833,2.844,,0.67,H,A,0.46,0.15,25.546,25.546,64.39,OHA,-2.12933,0.520039,0.00806773,0.706134 beta-lactamase_0_I229N,beta-lactamase_0_229,TEM-1,beta-lactamase_0,P62593,0.706178,NO,229,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.267,-4.128,2.861,,0.083,E,B,0.48,-0.76,1.69,,50,HHH,-1.58767,0.0500837,0.00477249,0.706178 beta-lactamase_0_D161S,beta-lactamase_0_161,TEM-1,beta-lactamase_0,P62593,0.706214,NO,161,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.891,-2.488,1.597,,0.341,,A,0.75,-0.52,0.795,,61.19,HAB,-0.961333,0.0500837,0.000897697,0.706214 beta-lactamase_2500_F70C,beta-lactamase_2500_70,TEM-1,beta-lactamase_2500,P62593,0.706219,NO,70,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.169,-4.871,3.702,,,H,A,0.58,-1.34,1.918,,63.99,PHB,-0.980667,0.361275,0.00193499,0.706219 beta-lactamase_0_P143Y,beta-lactamase_0_143,TEM-1,beta-lactamase_0,P62593,0.706319,NO,143,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.967,-4.337,3.37,,0.075,H,A,0.52,-0.37,11.868,11.868,66.78,OOB,-1.354,0.0500837,0.00114551,0.706319 beta-lactamase_0_P105N,beta-lactamase_0_105,TEM-1,beta-lactamase_0,P62593,0.706347,NO,105,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.813,-3.82,3.007,,0.226,T,A,0.52,0.8,3.48,,63.29,POH,-1.01533,0.0500837,0.0011981,0.706347 kka2_1:4_R226G,kka2_1:4_226,Kka2,kka2_1:4,P00552,0.706369,NO,226,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.392,-2.496,1.104,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.168804,0.0108032,0.706369 kka2_1:1_R226G,kka2_1:1_226,Kka2,kka2_1:1,P00552,0.706374,NO,226,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.392,-2.496,1.104,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.520039,0.0108032,0.706374 beta-lactamase_G216P,beta-lactamase_216,TEM-1,beta-lactamase,P62593,0.706429,NO,216,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.477,-3.898,2.421,4.91694,0.437,I,A,0.23,-0.58,1.718,,74.48,HOO,-1.68067,0.221079,0.00639568,0.706429 beta-lactamase_A40D,beta-lactamase_40,TEM-1,beta-lactamase,P62593,0.706455,NO,40,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.402,-3.685,2.283,4.9697,0.155,S,B,1.2,0.21,1.714,,73.78,OHB,-1.40267,0.221079,0.00490026,0.706455 kka2_1:2_V97G,kka2_1:2_97,Kka2,kka2_1:2,P00552,0.7065,NO,97,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.453,-3.796,2.343,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.295029,0.00737869,0.7065 beta-lactamase_625_I277C,beta-lactamase_625_277,TEM-1,beta-lactamase_625,P62593,0.706532,NO,277,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.213352,0.0169305,0.706532 Pab1_F170N,Pab1_170,Pab1,Pab1,P04147,0.706565,NO,170,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.269,-3.934,2.665,,0.331,E,B,0.87,-1.31,2.061,,79.72,OHH,-1.06367,0.175299,0.000540225,0.706565 beta-lactamase_2500_E62S,beta-lactamase_2500_62,TEM-1,beta-lactamase_2500,P62593,0.706702,NO,62,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.193,-3.245,2.052,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.361275,0.00264802,0.706702 kka2_1:1_G21A,kka2_1:1_21,Kka2,kka2_1:1,P00552,0.706765,NO,21,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.368,-2.331,0.963,,0.586,T,l,0.29,-0.75,10.291,10.291,71.59,HOH,-2.10167,0.520039,0.00709648,0.706765 beta-lactamase_2500_I54P,beta-lactamase_2500_54,TEM-1,beta-lactamase_2500,P62593,0.706768,NO,54,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-2.838,-4.045,1.207,,0.669,E,B,0.48,-0.14,3.946,,73.78,BHH,-2.337,0.361275,0.00403589,0.706768 kka2_1:2_D220Y,kka2_1:2_220,Kka2,kka2_1:2,P00552,0.706778,NO,220,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.787,-4.383,3.596,,,H,A,0.75,-1.14,0.745,,46.59,PAH,-1.152,0.295029,0.00158066,0.706778 kka2_1:1_A13G,kka2_1:1_13,Kka2,kka2_1:1,P00552,0.706833,NO,13,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.248,-2.748,0.5,,0.689,G,A,0.46,0.99,25.015,25.015,92.05,OHH,-1.646,0.520039,0.00784241,0.706833 beta-lactamase_2500_D212N,beta-lactamase_2500_212,TEM-1,beta-lactamase_2500,P62593,0.706919,NO,212,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.624,-1.899,0.275,,0.037,,b,0.75,-0.58,12.482,,74.48,HAB,-1.77667,0.361275,0.00644302,0.706919 beta-lactamase_0_G216K,beta-lactamase_0_216,TEM-1,beta-lactamase_0,P62593,0.707075,NO,216,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.477,-2.765,1.288,,0.437,I,A,0.29,-0.58,0.834,,74.48,HOO,-1.68067,0.0500837,0.00639568,0.707075 kka2_1:1_L165V,kka2_1:1_165,Kka2,kka2_1:1,P00552,0.707109,NO,165,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-2.453,-2.841,0.388,,0.299,,B,1.59,1.12,2.47,,64.39,OHH,-1.90967,0.520039,0.00801161,0.707109 gb1_L238E,gb1_238,gb1,gb1,P06654,0.707116,NO,238,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-2.98,-3.031,0.051,,,,,,,0.504,,45.54,PHB,-2.58633,0.177985,0.00205885,0.707116 beta-lactamase_R241G,beta-lactamase_241,TEM-1,beta-lactamase,P62593,0.707122,NO,241,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.433,-3.375,1.942,5.02621,0.094,E,B,0.68,-0.16,1.327,,50,PBO,-1.42967,0.221079,0.00452736,0.707122 beta-lactamase_0_Y95S,beta-lactamase_0_95,TEM-1,beta-lactamase_0,P62593,0.707165,NO,95,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-1.715,-3.776,2.061,,0.122,,b,0.21,-0.37,2.914,,77.62,BHP,-2.16167,0.0500837,0.00479449,0.707165 kka2_1:4_V185A,kka2_1:4_185,Kka2,kka2_1:4,P00552,0.707295,NO,185,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.045,-2.271,1.226,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.168804,0.00367031,0.707295 E1_Ubiquitin_L73C,E1_Ubiquitin_73,Uba1,E1_Ubiquitin,P0CG63,0.707339,NO,73,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.039,-4.454,3.415,,0.518,,B,1.3,1,,,,BHB,-1.175,0.18783,0.00111236,0.707339 beta-lactamase_0_L167Y,beta-lactamase_0_167,TEM-1,beta-lactamase_0,P62593,0.70736,NO,167,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.138,-4.067,2.929,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.0500837,0.00303566,0.70736 beta-lactamase_0_S68L,beta-lactamase_0_68,TEM-1,beta-lactamase_0,P62593,0.707394,NO,68,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-0.913,-3.407,2.494,,0.064,G,A,0.27,-1.03,1.441,,64.69,HPP,-1.37233,0.0500837,0.000800065,0.707394 kka2_1:4_A224L,kka2_1:4_224,Kka2,kka2_1:4,P00552,0.707426,NO,224,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.977,-3.204,2.227,,,H,A,0.46,-1.26,0.93,,63.64,HHP,-1.41033,0.168804,0.00352047,0.707426 beta-lactamase_156_L79N,beta-lactamase_156_79,TEM-1,beta-lactamase_156,P62593,0.70752,NO,79,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.842,-4.12,3.278,,0.007,H,A,0.55,-0.16,1.831,,50.35,HHP,-1.44333,0.111618,0.000947397,0.70752 kka2_1:1_L92Q,kka2_1:1_92,Kka2,kka2_1:1,P00552,0.707535,NO,92,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.893,-4.159,3.266,,0.007,E,B,0.55,-0.19,1.447,,63.26,HHH,-0.962,0.520039,0.00307177,0.707535 beta-lactamase_A215Q,beta-lactamase_215,TEM-1,beta-lactamase,P62593,0.707707,NO,215,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.503,-2.998,1.495,4.82164,,,a,0.75,-0.93,3.583,,74.48,HHO,-1.42633,0.221079,0.00544007,0.707707 kka2_1:8_A191E,kka2_1:8_191,Kka2,kka2_1:8,P00552,0.707709,NO,191,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.831,-3.502,2.671,,,,b,1.04,-0.94,1.306,,50,AHO,-0.868667,0.100394,0.00338807,0.707709 kka2_1:8_A191E,kka2_1:8_191,Kka2,kka2_1:8,P00552,0.707709,NO,191,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.831,-3.502,2.671,,,,b,1.04,-0.94,1.306,,50,AHO,-0.868667,0.100394,0.00338807,0.707709 kka2_1:4_V36A,kka2_1:4_36,Kka2,kka2_1:4,P00552,0.707743,NO,36,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-0.898,-2.963,2.065,,0.292,E,B,0.44,0.21,0.278,,52.27,HHH,-1.484,0.168804,0.00245633,0.707743 kka2_1:1_L103M,kka2_1:1_103,Kka2,kka2_1:1,P00552,0.707748,NO,103,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-2.362,-4.518,2.156,,0.394,T,A,0.55,-0.99,4.121,,63.64,HHP,-1.534,0.520039,0.00574792,0.707748 Pab1_A199E,Pab1_199,Pab1,Pab1,P04147,0.707833,NO,199,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.53,-3.447,1.917,,,,,,,1.479,,80.42,HHO,-1.50467,0.175299,0.00145024,0.707833 Pab1_I152T,Pab1_152,Pab1,Pab1,P04147,0.70784,NO,152,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.345,-3.235,1.89,,0.165,E,B,1.23,-0.71,1.288,,71.4,AHH,-1.59433,0.175299,0.000740963,0.70784 beta-lactamase_39_Y95D,beta-lactamase_39_95,TEM-1,beta-lactamase_39,P62593,0.707872,NO,95,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-1.715,-4.078,2.363,,0.122,,b,0.21,-0.37,2.341,,77.62,BHP,-2.16167,0.0495842,0.00479449,0.707872 kka2_1:1_Q155R,kka2_1:1_155,Kka2,kka2_1:1,P00552,0.707881,NO,155,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.606,-3.728,1.122,,0.525,T,A,0.4,1.49,4.415,,63.64,APA,-1.726,0.520039,0.00641853,0.707881 kka2_1:1_Q219H,kka2_1:1_219,Kka2,kka2_1:1,P00552,0.707915,NO,219,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-0.93,-4.282,3.352,,0.088,H,A,0.4,-0.85,1.917,,50,HPA,-1.05167,0.520039,0.00237913,0.707915 beta-lactamase_0_P165I,beta-lactamase_0_165,TEM-1,beta-lactamase_0,P62593,0.707917,NO,165,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.373,-3.815,2.442,,0.203,T,A,0.52,-0.31,3.242,,73.78,AOA,-1.359,0.0500837,0.00549538,0.707917 beta-lactamase_0_G85T,beta-lactamase_0_85,TEM-1,beta-lactamase_0,P62593,0.707923,NO,85,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.011,-3.637,2.626,,0.805,T,l,0.29,1.7,2.25,,63.64,HOP,-1.68733,0.0500837,0.00252173,0.707923 kka2_1:2_T28S,kka2_1:2_28,Kka2,kka2_1:2,P00552,0.707953,NO,28,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.883,-2.337,0.454,,0.353,S,B,0.22,2.02,2.655,,63.64,PPH,-1.74467,0.295029,0.00743084,0.707953 kka2_1:8_A119E,kka2_1:8_119,Kka2,kka2_1:8,P00552,0.708029,NO,119,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.073,-3.557,2.484,,0.019,H,A,0.46,-0.57,1.511,,71.59,AHH,-2.34,0.100394,0.00441074,0.708029 kka2_1:8_A119E,kka2_1:8_119,Kka2,kka2_1:8,P00552,0.708029,NO,119,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.073,-3.557,2.484,,0.019,H,A,0.46,-0.57,1.511,,71.59,AHH,-2.34,0.100394,0.00441074,0.708029 kka2_1:1_C209R,kka2_1:1_209,Kka2,kka2_1:1,P00552,0.708039,NO,209,C,R,CR,Special,PositiveCharge,5.07,6.34148,1.27148,180,121,174,53,108.5,173.4,64.9,-0.906,-4.184,3.278,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.520039,0.00260862,0.708039 beta-lactamase_2500_L73S,beta-lactamase_2500_73,TEM-1,beta-lactamase_2500,P62593,0.708057,NO,73,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.507,-3.664,2.157,,,H,A,0.55,-0.64,2.178,,67.83,HHH,-1.487,0.361275,0.00488983,0.708057 Pab1_F168V,Pab1_168,Pab1,Pab1,P04147,0.70811,NO,168,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.269,-3.174,1.905,,,,,,,0.789,,56.33,OHO,-1.10033,0.175299,0.00064061,0.70811 beta-lactamase_625_A215V,beta-lactamase_625_215,TEM-1,beta-lactamase_625,P62593,0.708118,NO,215,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.503,-3.464,1.961,,,,a,0.46,-0.93,3.583,,74.48,HHO,-1.42633,0.213352,0.00544007,0.708118 kka2_1:1_H8L,kka2_1:1_8,Kka2,kka2_1:1,P00552,0.708279,NO,8,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-2.759,-3.165,0.406,,,,,,,16.971,16.971,71.59,HBH,-2.25467,0.520039,0.00256422,0.708279 kka2_1:2_A41V,kka2_1:2_41,Kka2,kka2_1:2,P00552,0.708303,NO,41,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.879,-2.914,1.035,,0.184,.,B,0.46,-0.96,24.451,24.451,64.39,PHP,-2.477,0.295029,0.00543332,0.708303 kka2_1:8_L260P,kka2_1:8_260,Kka2,kka2_1:8,P00552,0.708509,NO,260,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.741,-4.133,3.392,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.100394,0.0233782,0.708509 kka2_1:8_L260P,kka2_1:8_260,Kka2,kka2_1:8,P00552,0.708509,NO,260,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.741,-4.133,3.392,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.100394,0.0233782,0.708509 beta-lactamase_0_V259D,beta-lactamase_0_259,TEM-1,beta-lactamase_0,P62593,0.70856,NO,259,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.0500837,0.0070773,0.70856 kka2_1:4_D227G,kka2_1:4_227,Kka2,kka2_1:4,P00552,0.7086,NO,227,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.758,-3.04,1.282,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.168804,0.00745029,0.7086 Pab1_I183D,Pab1_183,Pab1,Pab1,P04147,0.708659,NO,183,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.302,-3.789,2.487,,0.308,T,B,1,1.08,1.29,,75.56,HHA,-1.27167,0.175299,0.000574345,0.708659 beta-lactamase_A23E,beta-lactamase_23,TEM-1,beta-lactamase,P62593,0.708676,NO,23,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.548,-3.591,2.043,,,,,,,0.801,,93.01,HHB,-2.235,0.221079,0.00245563,0.708676 beta-lactamase_G76I,beta-lactamase_76,TEM-1,beta-lactamase,P62593,0.708676,NO,76,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.189,-3.948,2.759,4.73862,,H,A,2.05,-0.67,3.059,,67.83,OOH,-1.22267,0.221079,0.00476637,0.708676 beta-lactamase_P165Y,beta-lactamase_165,TEM-1,beta-lactamase,P62593,0.708676,NO,165,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.373,-4.331,2.958,5.33889,0.203,T,A,0.99,-0.31,0.414,,73.78,AOA,-1.359,0.221079,0.00549538,0.708676 beta-lactamase_Y103D,beta-lactamase_103,TEM-1,beta-lactamase,P62593,0.708676,NO,103,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-1.33,-3.794,2.464,5.71734,0.613,S,l,2.55,1.21,5.721,,63.29,AHP,-1.48767,0.221079,0.00443048,0.708676 kka2_1:2_W69R,kka2_1:2_69,Kka2,kka2_1:2,P00552,0.708685,NO,69,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-0.859,-4.184,3.325,,0.164,H,A,0.47,0.15,5.074,,38.64,PHH,-1.49967,0.295029,0.0012874,0.708685 kka2_1:1_D127Y,kka2_1:1_127,Kka2,kka2_1:1,P00552,0.709126,NO,127,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.364,-4.502,3.138,,0.573,.,B,0.75,0.45,3.414,,50.38,HAO,-1.51067,0.520039,0.00660501,0.709126 beta-lactamase_0_I229H,beta-lactamase_0_229,TEM-1,beta-lactamase_0,P62593,0.709168,NO,229,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.267,-4.969,3.702,,0.083,E,B,0.48,-0.76,1.69,,50,HHH,-1.58767,0.0500837,0.00477249,0.709168 kka2_1:8_L152P,kka2_1:8_152,Kka2,kka2_1:8,P00552,0.709226,NO,152,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.521,-4.119,2.598,,0.547,.,A,0.55,1.36,1.442,,63.64,OHH,-1.162,0.100394,0.00674868,0.709226 kka2_1:8_L152P,kka2_1:8_152,Kka2,kka2_1:8,P00552,0.709226,NO,152,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.521,-4.119,2.598,,0.547,.,A,0.55,1.36,1.442,,63.64,OHH,-1.162,0.100394,0.00674868,0.709226 kka2_1:8_R66L,kka2_1:8_66,Kka2,kka2_1:8,P00552,0.709226,NO,66,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-0.922,-3.421,2.499,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.100394,0.00161025,0.709226 kka2_1:8_R66L,kka2_1:8_66,Kka2,kka2_1:8,P00552,0.709226,NO,66,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-0.922,-3.421,2.499,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.100394,0.00161025,0.709226 WW_domain_E178K,WW_domain_178,Yap65,WW_domain,P46937,0.709237,NO,178,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.158,-2.784,1.626,5.22323,,,,,,,,,HAH,-1.299,0.153962,0.0016738,0.709237 kka2_1:1_L243P,kka2_1:1_243,Kka2,kka2_1:1,P00552,0.709318,NO,243,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-2.651,-4.123,1.472,,0.277,H,A,0.55,-0.67,4.334,,92.05,HHH,-2.03767,0.520039,0.00884927,0.709318 kka2_1:8_Q219P,kka2_1:8_219,Kka2,kka2_1:8,P00552,0.709386,NO,219,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-0.93,-3.727,2.797,,0.088,H,A,0.4,-0.85,0.897,,50,HPA,-1.05167,0.100394,0.00237913,0.709386 kka2_1:8_Q219P,kka2_1:8_219,Kka2,kka2_1:8,P00552,0.709386,NO,219,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-0.93,-3.727,2.797,,0.088,H,A,0.4,-0.85,0.897,,50,HPA,-1.05167,0.100394,0.00237913,0.709386 beta-lactamase_L49Q,beta-lactamase_49,TEM-1,beta-lactamase,P62593,0.709416,NO,49,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.897,-2.823,0.926,5.86005,0.131,T,A,1.3,0.04,3.112,,64.69,AHP,-1.99233,0.221079,0.00401477,0.709416 kka2_1:8_H188R,kka2_1:8_188,Kka2,kka2_1:8,P00552,0.709425,NO,188,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-0.913,-3.509,2.596,,0.006,,A,0.87,-1.02,1.241,,47.73,PBO,-0.927333,0.100394,0.00273139,0.709425 kka2_1:8_H188R,kka2_1:8_188,Kka2,kka2_1:8,P00552,0.709425,NO,188,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-0.913,-3.509,2.596,,0.006,,A,0.87,-1.02,1.241,,47.73,PBO,-0.927333,0.100394,0.00273139,0.709425 beta-lactamase_625_D48V,beta-lactamase_625_48,TEM-1,beta-lactamase_625,P62593,0.709437,NO,48,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.101,-3.719,2.618,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.213352,0.0027273,0.709437 beta-lactamase_P20C,beta-lactamase_20,TEM-1,beta-lactamase,P62593,0.709533,NO,20,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.74,-4.743,3.003,,,,,,,0.368,,67.83,HOH,-1.765,0.221079,0.00235322,0.709533 kka2_1:1_P12T,kka2_1:1_12,Kka2,kka2_1:1,P00552,0.709536,NO,12,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.853,-3.419,2.566,,,.,B,0.52,1.25,0.261,,48.11,POH,-1.80767,0.520039,0.00500011,0.709536 beta-lactamase_156_A133V,beta-lactamase_156_133,TEM-1,beta-lactamase_156,P62593,0.709544,NO,133,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.186,-3.341,2.155,,,H,A,0.46,-0.86,0.805,,67.83,HHP,-0.988333,0.111618,0.00468022,0.709544 beta-lactamase_N134T,beta-lactamase_134,TEM-1,beta-lactamase,P62593,0.709564,NO,134,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-0.879,-3.245,2.366,5.07245,0.138,H,A,0.09,-0.6,1.441,,53.15,HPH,-1.02233,0.221079,0.000644786,0.709564 kka2_1:1_Q26H,kka2_1:1_26,Kka2,kka2_1:1,P00552,0.709621,NO,26,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.18,-3.435,1.255,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.520039,0.00708962,0.709621 kka2_1:1_A166R,kka2_1:1_166,Kka2,kka2_1:1,P00552,0.709654,NO,166,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.407,-3.179,0.772,,0.534,.,B,0.46,1.03,1.147,,71.59,HHO,-2.421,0.520039,0.00799912,0.709654 Pab1_A141P,Pab1_141,Pab1,Pab1,P04147,0.709667,NO,141,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.461,-3.583,2.122,,0.34,H,A,0.52,-0.27,2.15,,79.03,BHH,-1.19433,0.175299,0.00165974,0.709667 Ubiquitin_D58L,Ubiquitin_58,Uba1,Ubiquitin,P0CG48,0.709677,NO,58,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.622,-2.76,1.138,5.06391,0.457,G,A,,-0.54,,,,PAH,-1.60267,0.205827,0.000639847,0.709677 Ubiquitin_F4Y,Ubiquitin_4,Uba1,Ubiquitin,P0CG48,0.709677,NO,4,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.534,-2.08,0.546,4.77459,0.059,E,B,,-0.46,,,,HHH,-1.504,0.205827,0.000805043,0.709677 Ubiquitin_I3S,Ubiquitin_3,Uba1,Ubiquitin,P0CG48,0.709677,NO,3,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.402,-3.572,2.17,4.80819,,E,B,,-0.78,,,,PHH,-1.54533,0.205827,0.000836911,0.709677 Ubiquitin_L67A,Ubiquitin_67,Uba1,Ubiquitin,P0CG48,0.709677,NO,67,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.435,-3.156,1.721,4.92156,,E,B,1.19,-1.02,6.371,6.371,30.8,PHB,-1.628,0.205827,0.000482727,0.709677 Ubiquitin_T7P,Ubiquitin_7,Uba1,Ubiquitin,P0CG48,0.709677,NO,7,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.415,-2.707,1.292,4.954,0.094,E,B,0.43,-0.78,0.805,,21.31,BPH,-1.41033,0.205827,0.000647855,0.709677 beta-lactamase_39_T179G,beta-lactamase_39_179,TEM-1,beta-lactamase_39,P62593,0.70969,NO,179,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.085,-3.296,2.211,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.0495842,0.00226045,0.70969 kka2_1:4_W91C,kka2_1:4_91,Kka2,kka2_1:4,P00552,0.709718,NO,91,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-1.178,-5.004,3.826,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.168804,0.00358653,0.709718 beta-lactamase_0_G142F,beta-lactamase_0_142,TEM-1,beta-lactamase_0,P62593,0.709782,NO,142,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.707,-4.29,3.583,,0.034,,p,0.29,-0.64,1.947,,64.69,OOO,-0.834,0.0500837,0.00060149,0.709782 beta-lactamase_156_M209T,beta-lactamase_156_209,TEM-1,beta-lactamase_156,P62593,0.709793,NO,209,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.442,-3.52,2.078,,,H,A,0.55,-0.97,1.066,,64.69,HHA,-1.52633,0.111618,0.00625021,0.709793 kka2_1:4_D52K,kka2_1:4_52,Kka2,kka2_1:4,P00552,0.709807,NO,52,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.271,-3.096,0.825,,0.22,E,B,0.75,0.8,0.349,,71.59,PAH,-2.38367,0.168804,0.00175694,0.709807 beta-lactamase_0_W208I,beta-lactamase_0_208,TEM-1,beta-lactamase_0,P62593,0.70983,NO,208,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-0.818,-4.01,3.192,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.0500837,0.00126609,0.70983 kka2_1:1_E149V,kka2_1:1_149,Kka2,kka2_1:1,P00552,0.70985,NO,149,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.994,-3.648,1.654,,0.674,H,A,1.04,1.63,3.671,,71.59,HAH,-1.59667,0.520039,0.00803343,0.70985 beta-lactamase_R255T,beta-lactamase_255,TEM-1,beta-lactamase,P62593,0.709874,NO,255,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.266,-3.615,1.349,5.55882,0.141,E,B,0.68,0.38,1.199,,63.99,PBH,-2.00433,0.221079,0.00499612,0.709874 beta-lactamase_2500_T186P,beta-lactamase_2500_186,TEM-1,beta-lactamase_2500,P62593,0.710006,NO,186,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.522,-3.945,1.423,,0.396,H,A,0.22,-0.28,2.144,,77.62,HPP,-1.77633,0.361275,0.00485034,0.710006 beta-lactamase_156_Y44A,beta-lactamase_156_44,TEM-1,beta-lactamase_156,P62593,0.710058,NO,44,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-2.547,-2.301,-0.246,,,E,B,0.21,-0.45,2.184,,73.78,OHH,-1.86267,0.111618,0.00426364,0.710058 beta-lactamase_0_V101G,beta-lactamase_0_101,TEM-1,beta-lactamase_0,P62593,0.710062,NO,101,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.295,-3.721,2.426,,0.342,,B,0.44,0,1.61,,73.08,HHA,-1.54367,0.0500837,0.00374492,0.710062 beta-lactamase_R202L,beta-lactamase_202,TEM-1,beta-lactamase,P62593,0.710062,NO,202,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.292,-3.422,2.13,5.16273,0.188,H,A,0.68,0.62,1.918,,77.62,PBP,-1.54767,0.221079,0.00321899,0.710062 gb1_Y259T,gb1_259,gb1,gb1,P06654,0.710069,NO,259,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-1.78,-3.512,1.732,,,,,,,0.131,,11.83,PHH,-1.787,0.177985,0.00464313,0.710069 beta-lactamase_L192S,beta-lactamase_192,TEM-1,beta-lactamase,P62593,0.710165,NO,192,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.254,-3.616,2.362,5.68899,0.095,H,A,1.3,0.35,1.756,,60.14,HHP,-1.41833,0.221079,0.00558728,0.710165 kka2_1:4_S105R,kka2_1:4_105,Kka2,kka2_1:4,P00552,0.710275,NO,105,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.945,-3.214,1.269,,0.056,S,B,0.77,-1.04,3.442,,65.53,PPB,-2.17033,0.168804,0.00847233,0.710275 beta-lactamase_0_T107P,beta-lactamase_0_107,TEM-1,beta-lactamase_0,P62593,0.710276,NO,107,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.117,-3.706,2.589,,,G,A,0.22,-0.06,3.73,,67.83,HPA,-1.265,0.0500837,0.00239347,0.710276 kka2_1:8_G99F,kka2_1:8_99,Kka2,kka2_1:8,P00552,0.710339,NO,99,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.596,-4.32,3.724,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.100394,0.00186055,0.710339 kka2_1:8_G99F,kka2_1:8_99,Kka2,kka2_1:8,P00552,0.710339,NO,99,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.596,-4.32,3.724,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.100394,0.00186055,0.710339 kka2_1:1_G21L,kka2_1:1_21,Kka2,kka2_1:1,P00552,0.710355,NO,21,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.368,-3.794,2.426,,0.586,T,l,0.29,-0.75,10.291,10.291,71.59,HOH,-2.10167,0.520039,0.00709648,0.710355 kka2_1:1_L93P,kka2_1:1_93,Kka2,kka2_1:1,P00552,0.71045,NO,93,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.815,-4.131,3.316,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.520039,0.00131498,0.71045 beta-lactamase_625_E195F,beta-lactamase_625_195,TEM-1,beta-lactamase_625,P62593,0.710532,NO,195,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.186,-4.475,2.289,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.213352,0.00496565,0.710532 beta-lactamase_0_Q97I,beta-lactamase_0_97,TEM-1,beta-lactamase_0,P62593,0.710713,NO,97,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.072,-4.072,2,,0.823,G,A,0.64,2.42,16.954,16.954,77.62,PPP,-2.43833,0.0500837,0.0045116,0.710713 beta-lactamase_2500_K109C,beta-lactamase_2500_109,TEM-1,beta-lactamase_2500,P62593,0.710788,NO,109,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.734,-5.237,3.503,,0.787,G,A,2.34,2.21,0.998,,72.73,ABB,-1.63333,0.361275,0.00462493,0.710788 beta-lactamase_2500_S57D,beta-lactamase_2500_57,TEM-1,beta-lactamase_2500,P62593,0.710863,NO,57,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.918,-3.634,1.716,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.361275,0.00492804,0.710863 beta-lactamase_0_L199K,beta-lactamase_0_199,TEM-1,beta-lactamase_0,P62593,0.71089,NO,199,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-2.942,-2.994,0.052,,0.832,H,A,0.55,0.42,10.85,10.85,77.62,PHH,-2.32933,0.0500837,0.0048649,0.71089 beta-lactamase_39_M66P,beta-lactamase_39_66,TEM-1,beta-lactamase_39,P62593,0.71089,NO,66,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.362,-4.047,2.685,,0.013,,A,0.55,-0.7,1.319,,73.08,OHH,-1.49567,0.0495842,0.00412876,0.71089 kka2_1:2_D261Y,kka2_1:2_261,Kka2,kka2_1:2,P00552,0.710939,NO,261,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.708,-4.416,3.708,,0.146,G,A,0.75,-0.33,,,,HAA,-0.759333,0.295029,0.0224846,0.710939 beta-lactamase_156_R59E,beta-lactamase_156_59,TEM-1,beta-lactamase_156,P62593,0.711021,NO,59,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.345,-3.322,1.977,,0.329,S,L,1.2,-0.09,2.995,,73.08,HBO,-2.24267,0.111618,0.00318082,0.711021 gb1_G240R,gb1_240,gb1,gb1,P06654,0.711041,NO,240,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.921,-3.668,2.747,,,,,,,,,,BOA,-1.87867,0.177985,0.00270792,0.711041 kka2_1:2_P194A,kka2_1:2_194,Kka2,kka2_1:2,P00552,0.711053,NO,194,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.846,-3.118,2.272,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.295029,0.00314194,0.711053 kka2_1:1_H188N,kka2_1:1_188,Kka2,kka2_1:1,P00552,0.711065,NO,188,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-0.913,-3.295,2.382,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.520039,0.00273139,0.711065 kka2_1:8_R226S,kka2_1:8_226,Kka2,kka2_1:8,P00552,0.711093,NO,226,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.392,-2.638,1.246,,0.222,H,A,0.16,-0.71,3.818,,56.06,PBA,-1.84767,0.100394,0.0108032,0.711093 kka2_1:8_R226S,kka2_1:8_226,Kka2,kka2_1:8,P00552,0.711093,NO,226,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.392,-2.638,1.246,,0.222,H,A,0.16,-0.71,3.818,,56.06,PBA,-1.84767,0.100394,0.0108032,0.711093 beta-lactamase_L197N,beta-lactamase_197,TEM-1,beta-lactamase,P62593,0.711182,NO,197,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.853,-4.12,3.267,5.19172,0.007,S,B,1.3,0.33,1.756,,60.14,HHP,-1.833,0.221079,0.00144602,0.711182 kka2_1:1_G233C,kka2_1:1_233,Kka2,kka2_1:1,P00552,0.711211,NO,233,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.748,-5.16,4.412,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.520039,0.00232366,0.711211 beta-lactamase_2500_G90C,beta-lactamase_2500_90,TEM-1,beta-lactamase_2500,P62593,0.711359,NO,90,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-2.091,-5.167,3.076,,0.598,T,A,0.29,0.32,1.2,,77.62,HOB,-1.52633,0.361275,0.00490273,0.711359 beta-lactamase_2500_S283G,beta-lactamase_2500_283,TEM-1,beta-lactamase_2500,P62593,0.711394,NO,283,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.361275,0.0429138,0.711394 kka2_1:8_H188M,kka2_1:8_188,Kka2,kka2_1:8,P00552,0.71141,NO,188,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-0.913,-4.701,3.788,,0.006,,A,0.87,-1.02,1.241,,47.73,PBO,-0.927333,0.100394,0.00273139,0.71141 kka2_1:8_H188M,kka2_1:8_188,Kka2,kka2_1:8,P00552,0.71141,NO,188,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-0.913,-4.701,3.788,,0.006,,A,0.87,-1.02,1.241,,47.73,PBO,-0.927333,0.100394,0.00273139,0.71141 kka2_1:2_L81P,kka2_1:2_81,Kka2,kka2_1:2,P00552,0.711421,NO,81,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.427,-4.19,2.763,,0.46,E,A,1.59,-0.14,1.895,,63.64,HHA,-1.50567,0.295029,0.00805839,0.711421 beta-lactamase_0_T193A,beta-lactamase_0_193,TEM-1,beta-lactamase_0,P62593,0.711493,NO,193,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.914,-2.618,0.704,,0.439,H,a,0.22,0.33,11.546,11.546,63.99,HPO,-1.52133,0.0500837,0.00482669,0.711493 kka2_1:1_I254Q,kka2_1:1_254,Kka2,kka2_1:1,P00552,0.711575,NO,254,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.933,-4.193,2.26,,0.135,H,A,1.52,-0.6,1.859,,71.59,BHH,-1.668,0.520039,0.0132375,0.711575 Pab1_H172N,Pab1_172,Pab1,Pab1,P04147,0.711579,NO,172,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-1.21,-3.04,1.83,,0.076,E,B,0.35,-0.87,,,,HBH,-1.26667,0.175299,0.000296642,0.711579 beta-lactamase_G39P,beta-lactamase_39,TEM-1,beta-lactamase,P62593,0.711637,NO,39,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.864,-3.073,1.209,5.35574,0.701,T,L,0.23,0.47,29.926,29.926,77.62,HOH,-1.53633,0.221079,0.00487611,0.711637 beta-lactamase_2500_E195W,beta-lactamase_2500_195,TEM-1,beta-lactamase_2500,P62593,0.711682,NO,195,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.186,-5.555,3.369,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.361275,0.00496565,0.711682 beta-lactamase_2500_G265A,beta-lactamase_2500_265,TEM-1,beta-lactamase_2500,P62593,0.711733,NO,265,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.361275,0.00811926,0.711733 kka2_1:1_L223R,kka2_1:1_223,Kka2,kka2_1:1,P00552,0.711745,NO,223,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.861,-4.044,3.183,,,H,A,0.55,-1.24,1.268,,50,HHH,-0.854333,0.520039,0.00253574,0.711745 kka2_1:4_Q100P,kka2_1:4_100,Kka2,kka2_1:4,P00552,0.711752,NO,100,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.77,-4.125,1.355,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.168804,0.0066405,0.711752 PSD95pdz3_V328Y,PSD95pdz3_328,PSD95pdz3,PSD95pdz3,P31016,0.711792,NO,328,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.465,-3.619,2.154,5.28275,,,,,16.8775,,,,HHO,-1.36767,0.0758425,0.000986706,0.711792 kka2_1:1_K138Q,kka2_1:1_138,Kka2,kka2_1:1,P00552,0.711799,NO,138,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-2.5,-2.969,0.469,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.520039,0.00628542,0.711799 kka2_1:2_G213R,kka2_1:2_213,Kka2,kka2_1:2,P00552,0.711824,NO,213,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.596,-3.961,3.365,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.295029,0.00187654,0.711824 beta-lactamase_625_Y103L,beta-lactamase_625_103,TEM-1,beta-lactamase_625,P62593,0.711891,NO,103,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-1.33,-3.402,2.072,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.213352,0.00443048,0.711891 Pab1_N132I,Pab1_132,Pab1,Pab1,P04147,0.711891,NO,132,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-1.079,-3.827,2.748,,0.412,S,l,,0.9,,,,BPH,-1.067,0.175299,0.000347671,0.711891 beta-lactamase_2500_K109P,beta-lactamase_2500_109,TEM-1,beta-lactamase_2500,P62593,0.711906,NO,109,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.734,-2.825,1.091,,0.787,G,A,2.34,2.21,0.998,,72.73,ABB,-1.63333,0.361275,0.00462493,0.711906 kka2_1:8_H135D,kka2_1:8_135,Kka2,kka2_1:8,P00552,0.711963,NO,135,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-1.331,-3.636,2.305,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.100394,0.00532566,0.711963 kka2_1:8_H135D,kka2_1:8_135,Kka2,kka2_1:8,P00552,0.711963,NO,135,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-1.331,-3.636,2.305,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.100394,0.00532566,0.711963 beta-lactamase_156_L135W,beta-lactamase_156_135,TEM-1,beta-lactamase_156,P62593,0.711966,NO,135,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.002,-5.166,4.164,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.111618,0.00244423,0.711966 beta-lactamase_0_G43K,beta-lactamase_0_43,TEM-1,beta-lactamase_0,P62593,0.712002,NO,43,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.62,-3.682,3.062,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.0500837,0.00120151,0.712002 kka2_1:1_R121L,kka2_1:1_121,Kka2,kka2_1:1,P00552,0.712024,NO,121,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.552,-2.477,0.925,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.520039,0.00523326,0.712024 beta-lactamase_0_S104Y,beta-lactamase_0_104,TEM-1,beta-lactamase_0,P62593,0.712044,NO,104,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.015,-4.223,3.208,,0.04,,b,0.27,0.57,1.148,,63.29,HPO,-1.05267,0.0500837,0.00218083,0.712044 kka2_1:4_A144G,kka2_1:4_144,Kka2,kka2_1:4,P00552,0.712048,NO,144,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.859,-3.076,2.217,,,H,A,0.46,0.21,6.844,,52.65,BHB,-1.72933,0.168804,0.00231095,0.712048 kka2_1:4_D127V,kka2_1:4_127,Kka2,kka2_1:4,P00552,0.712071,NO,127,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.364,-3.744,2.38,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.168804,0.00660501,0.712071 kka2_1:2_G88A,kka2_1:2_88,Kka2,kka2_1:2,P00552,0.712092,NO,88,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.689,-2.52,0.831,,0.54,S,l,0.75,1.51,2.814,,65.53,HOB,-1.718,0.295029,0.00685559,0.712092 beta-lactamase_2500_M270N,beta-lactamase_2500_270,TEM-1,beta-lactamase_2500,P62593,0.712099,NO,270,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.723,,,,0.422,H,A,1.59,1.15,2.029,,64.34,PHA,-1.70933,0.361275,0.00767762,0.712099 beta-lactamase_0_D161T,beta-lactamase_0_161,TEM-1,beta-lactamase_0,P62593,0.712101,NO,161,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.891,-3.414,2.523,,0.341,,A,0.75,-0.52,0.795,,61.19,HAB,-0.961333,0.0500837,0.000897697,0.712101 beta-lactamase_N130D,beta-lactamase_130,TEM-1,beta-lactamase,P62593,0.712105,NO,130,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-0.798,-3.019,2.221,5.26686,0.069,H,A,1.08,-0.74,,,,APP,-0.980667,0.221079,0.000683376,0.712105 beta-lactamase_39_G236K,beta-lactamase_39_236,TEM-1,beta-lactamase_39,P62593,0.712139,NO,236,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.784,-3.651,2.867,,0.241,,b,0.29,-0.59,1.883,,64.69,HOO,-1.025,0.0495842,0.00162372,0.712139 beta-lactamase_0_E145H,beta-lactamase_0_145,TEM-1,beta-lactamase_0,P62593,0.712196,NO,145,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.357,-4.656,2.299,,0.545,H,A,1.04,0.79,1.199,,77.62,BAH,-2.069,0.0500837,0.00553285,0.712196 PSD95pdz3_S339W,PSD95pdz3_339,PSD95pdz3,PSD95pdz3,P31016,0.712235,NO,339,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.519,-5.004,3.485,5.34493,,,,,12.2167,,,,HPH,-1.55767,0.0758425,0.00084982,0.712235 beta-lactamase_0_A211N,beta-lactamase_0_211,TEM-1,beta-lactamase_0,P62593,0.712244,NO,211,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.896,-2.729,0.833,,0.369,T,A,0.46,-0.69,8.527,8.527,77.62,AHA,-1.94633,0.0500837,0.00648183,0.712244 kka2_1:4_D154I,kka2_1:4_154,Kka2,kka2_1:4,P00552,0.712443,NO,154,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.876,-4.094,3.218,,0.457,,b,0.29,1.48,15.641,15.641,52.65,HAP,-1.52467,0.168804,0.00292633,0.712443 beta-lactamase_0_T107G,beta-lactamase_0_107,TEM-1,beta-lactamase_0,P62593,0.712455,NO,107,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.117,-3.227,2.11,,,G,A,0.22,-0.06,3.73,,67.83,HPA,-1.265,0.0500837,0.00239347,0.712455 Pab1_I152C,Pab1_152,Pab1,Pab1,P04147,0.71248,NO,152,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.345,-4.53,3.185,,0.165,E,B,1.23,-0.71,1.288,,71.4,AHH,-1.59433,0.175299,0.000740963,0.71248 beta-lactamase_39_G240W,beta-lactamase_39_240,TEM-1,beta-lactamase_39,P62593,0.712493,NO,240,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.0495842,0.00591201,0.712493 PSD95pdz3_L367R,PSD95pdz3_367,PSD95pdz3,PSD95pdz3,P31016,0.712527,NO,367,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.347,-3.615,2.268,5.47696,,,,,17.0063,,,,AHB,-1.39767,0.0758425,0.000466436,0.712527 kka2_1:2_R38Q,kka2_1:2_38,Kka2,kka2_1:2,P00552,0.712564,NO,38,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.207,-3.749,2.542,,0.355,E,B,1.2,-1.13,6.872,6.872,52.27,HBH,-1.28567,0.295029,0.00372499,0.712564 beta-lactamase_0_I229P,beta-lactamase_0_229,TEM-1,beta-lactamase_0,P62593,0.712609,NO,229,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.267,-4.079,2.812,,0.083,E,B,0.48,-0.76,1.69,,50,HHH,-1.58767,0.0500837,0.00477249,0.712609 beta-lactamase_2500_E279F,beta-lactamase_2500_279,TEM-1,beta-lactamase_2500,P62593,0.712629,NO,279,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.361275,0.0192826,0.712629 kka2_1:2_Y218L,kka2_1:2_218,Kka2,kka2_1:2,P00552,0.712652,NO,218,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-1.438,-3.412,1.974,,0.122,H,A,0.21,-0.69,1.022,,56.06,BHP,-1.17533,0.295029,0.0126098,0.712652 beta-lactamase_0_T193N,beta-lactamase_0_193,TEM-1,beta-lactamase_0,P62593,0.712699,NO,193,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.914,-2.715,0.801,,0.439,H,a,0.22,0.33,11.546,11.546,63.99,HPO,-1.52133,0.0500837,0.00482669,0.712699 beta-lactamase_K30D,beta-lactamase_30,TEM-1,beta-lactamase,P62593,0.712748,NO,30,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-2.307,-3.567,1.26,5.30605,0.142,H,A,1.82,-0.65,2.434,,93.01,HBH,-2.32833,0.221079,0.00448593,0.712748 kka2_1:8_F203H,kka2_1:8_203,Kka2,kka2_1:8,P00552,0.712752,NO,203,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-0.911,-4.571,3.66,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.100394,0.00318738,0.712752 kka2_1:8_F203H,kka2_1:8_203,Kka2,kka2_1:8,P00552,0.712752,NO,203,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-0.911,-4.571,3.66,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.100394,0.00318738,0.712752 kka2_1:8_S204H,kka2_1:8_204,Kka2,kka2_1:8,P00552,0.71279,NO,204,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.353,-4.723,3.37,,0.144,E,A,0.27,-1.2,0.368,,65.53,HPO,-0.953333,0.100394,0.00881794,0.71279 kka2_1:8_S204H,kka2_1:8_204,Kka2,kka2_1:8,P00552,0.71279,NO,204,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.353,-4.723,3.37,,0.144,E,A,0.27,-1.2,0.368,,65.53,HPO,-0.953333,0.100394,0.00881794,0.71279 kka2_1:4_A34G,kka2_1:4_34,Kka2,kka2_1:4,P00552,0.712833,NO,34,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.928,-2.969,2.041,,0.417,.,B,0.46,2.29,0.262,,52.27,AHH,-1.747,0.168804,0.00343484,0.712833 kka2_1:4_V214R,kka2_1:4_214,Kka2,kka2_1:4,P00552,0.712841,NO,214,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.261,-3.109,1.848,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.168804,0.00692782,0.712841 kka2_1:4_H106F,kka2_1:4_106,Kka2,kka2_1:4,P00552,0.712903,NO,106,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-3.13,-4.435,1.305,,1.065,.,a,0.17,-0.95,16.74,16.74,71.59,PBH,-2.10433,0.168804,0.00730778,0.712903 gb1_G240Y,gb1_240,gb1,gb1,P06654,0.712968,NO,240,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.921,-4.123,3.202,,,,,,,,,,BOA,-1.87867,0.177985,0.00270792,0.712968 beta-lactamase_H110D,beta-lactamase_110,TEM-1,beta-lactamase,P62593,0.713078,NO,110,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-1.706,-3.678,1.972,5.52635,0.341,G,a,0.35,1.08,31.31,31.31,64.69,BBH,-1.73333,0.221079,0.00441499,0.713078 beta-lactamase_2500_W208F,beta-lactamase_2500_208,TEM-1,beta-lactamase_2500,P62593,0.713089,NO,208,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-0.818,-3.392,2.574,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.361275,0.00126609,0.713089 kka2_1:8_D159L,kka2_1:8_159,Kka2,kka2_1:8,P00552,0.713121,NO,159,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.82,-3.871,3.051,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.100394,0.0030485,0.713121 kka2_1:8_D159L,kka2_1:8_159,Kka2,kka2_1:8,P00552,0.713121,NO,159,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.82,-3.871,3.051,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.100394,0.0030485,0.713121 beta-lactamase_2500_P25G,beta-lactamase_2500_25,TEM-1,beta-lactamase_2500,P62593,0.713141,NO,25,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.526,-2.198,0.672,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.361275,0.00347571,0.713141 kka2_1:4_I207C,kka2_1:4_207,Kka2,kka2_1:4,P00552,0.713147,NO,207,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.175,-4.752,3.577,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.168804,0.00611824,0.713147 kka2_1:4_E59K,kka2_1:4_59,Kka2,kka2_1:4,P00552,0.713169,NO,59,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-0.952,-3.163,2.211,,0.187,.,L,1.04,0.62,3.408,,50.38,PAH,-1.53,0.168804,0.00280355,0.713169 beta-lactamase_2500_K32C,beta-lactamase_2500_32,TEM-1,beta-lactamase_2500,P62593,0.713215,NO,32,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.984,-5.093,3.109,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.361275,0.00401283,0.713215 PSD95pdz3_I388N,PSD95pdz3_388,PSD95pdz3,PSD95pdz3,P31016,0.713232,NO,388,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.63,-3.805,2.175,5.17282,,,,,16.0025,,,,PHH,-1.54967,0.0758425,0.000151216,0.713232 beta-lactamase_0_D83Y,beta-lactamase_0_83,TEM-1,beta-lactamase_0,P62593,0.713275,NO,83,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.066,-4.396,3.33,,0.354,H,A,0.75,0.22,0.617,,48.95,HAH,-1.34733,0.0500837,0.00205968,0.713275 kka2_1:2_S204I,kka2_1:2_204,Kka2,kka2_1:2,P00552,0.713312,NO,204,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.353,-3.845,2.492,,0.144,E,A,0.27,-1.2,2.442,,65.53,HPO,-0.953333,0.295029,0.00881794,0.713312 beta-lactamase_W286I,beta-lactamase_286,TEM-1,beta-lactamase,P62593,0.71333,NO,286,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-1.111,-3.827,2.716,6.64456,0.492,,?,0.01,0.6,,,,BHX,-1.478,0.221079,,0.71333 beta-lactamase_2500_I125C,beta-lactamase_2500_125,TEM-1,beta-lactamase_2500,P62593,0.713388,NO,125,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.441,-4.783,3.342,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.361275,0.00383964,0.713388 beta-lactamase_625_V82D,beta-lactamase_625_82,TEM-1,beta-lactamase_625,P62593,0.713427,NO,82,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.325,-3.879,2.554,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.213352,0.00397046,0.713427 kka2_1:4_A137G,kka2_1:4_137,Kka2,kka2_1:4,P00552,0.713476,NO,137,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.156,-3.64,1.484,,0.029,H,A,0.46,0.34,2.227,,63.26,PHB,-2.559,0.168804,0.00515054,0.713476 beta-lactamase_0_S128N,beta-lactamase_0_128,TEM-1,beta-lactamase_0,P62593,0.71348,NO,128,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-0.84,-3.223,2.383,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.0500837,0.00071483,0.71348 kka2_1:4_W24T,kka2_1:4_24,Kka2,kka2_1:4,P00552,0.713769,NO,24,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-1.779,-3.697,1.918,,0.477,E,B,1.51,-0.21,2.666,,56.06,AHH,-2.24467,0.168804,0.00631564,0.713769 kka2_1:1_Q100K,kka2_1:1_100,Kka2,kka2_1:1,P00552,0.713812,NO,100,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.77,-3.068,0.298,,0.646,E,B,0.4,-0.79,15.116,15.116,71.59,OPA,-1.46467,0.520039,0.0066405,0.713812 kka2_1:8_H188N,kka2_1:8_188,Kka2,kka2_1:8,P00552,0.713854,NO,188,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-0.913,-3.295,2.382,,0.006,,A,0.87,-1.02,1.241,,47.73,PBO,-0.927333,0.100394,0.00273139,0.713854 kka2_1:8_H188N,kka2_1:8_188,Kka2,kka2_1:8,P00552,0.713854,NO,188,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-0.913,-3.295,2.382,,0.006,,A,0.87,-1.02,1.241,,47.73,PBO,-0.927333,0.100394,0.00273139,0.713854 beta-lactamase_39_N130V,beta-lactamase_39_130,TEM-1,beta-lactamase_39,P62593,0.713863,NO,130,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-0.798,-3.754,2.956,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.0495842,0.000683376,0.713863 kka2_1:2_L152W,kka2_1:2_152,Kka2,kka2_1:2,P00552,0.713919,NO,152,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.521,-5.416,3.895,,0.547,.,A,0.55,1.36,4.526,,63.64,OHH,-1.162,0.295029,0.00674868,0.713919 kka2_1:1_D250Y,kka2_1:1_250,Kka2,kka2_1:1,P00552,0.713992,NO,250,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.015,-4.409,3.394,,0.274,.,b,0.75,-0.46,4.177,,51.89,OAP,-1.83933,0.520039,0.0177103,0.713992 kka2_1:2_A191E,kka2_1:2_191,Kka2,kka2_1:2,P00552,0.714036,NO,191,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.831,-3.502,2.671,,,.,b,0.46,-0.94,2.046,,50,AHO,-0.868667,0.295029,0.00338807,0.714036 beta-lactamase_0_I54S,beta-lactamase_0_54,TEM-1,beta-lactamase_0,P62593,0.714077,NO,54,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-2.838,-3.459,0.621,,0.669,E,B,0.48,-0.14,0.541,,73.78,BHH,-2.337,0.0500837,0.00403589,0.714077 kka2_1:1_E169D,kka2_1:1_169,Kka2,kka2_1:1,P00552,0.714086,NO,169,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.996,-1.998,0.002,,0.422,H,A,1.04,0.3,7.546,7.546,65.53,HAH,-1.755,0.520039,0.00730086,0.714086 beta-lactamase_0_P250D,beta-lactamase_0_250,TEM-1,beta-lactamase_0,P62593,0.714162,NO,250,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-2.335,-1.83,-0.505,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.0500837,0.00550899,0.714162 kka2_1:2_P167W,kka2_1:2_167,Kka2,kka2_1:2,P00552,0.714236,NO,167,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-2.403,-5.529,3.126,,0.18,H,A,0.52,0.75,3.6,,64.39,HOH,-2.26633,0.295029,0.00543203,0.714236 WW_domain_G185C,WW_domain_185,Yap65,WW_domain,P46937,0.714263,NO,185,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.861,-4.864,4.003,6.22337,,,,,,,,,POP,-1.194,0.153962,0.00199178,0.714263 kka2_1:8_L92P,kka2_1:8_92,Kka2,kka2_1:8,P00552,0.714325,NO,92,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.893,-4.134,3.241,,0.007,E,B,1.59,-0.19,1.719,,63.26,HHH,-0.962,0.100394,0.00307177,0.714325 kka2_1:8_L92P,kka2_1:8_92,Kka2,kka2_1:8,P00552,0.714325,NO,92,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.893,-4.134,3.241,,0.007,E,B,1.59,-0.19,1.719,,63.26,HHH,-0.962,0.100394,0.00307177,0.714325 PSD95pdz3_G324D,PSD95pdz3_324,PSD95pdz3,PSD95pdz3,P31016,0.714353,NO,324,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.008,-3.15,2.142,4.98881,,,,,10.4525,,,,HOH,-1.293,0.0758425,0.00103462,0.714353 beta-lactamase_M67E,beta-lactamase_67,TEM-1,beta-lactamase,P62593,0.714385,NO,67,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-2.231,-3.761,1.53,4.9618,0.006,G,P,1.07,-0.81,1.463,,65.03,HHP,-1.502,0.221079,0.00409753,0.714385 E1_Ubiquitin_R72K,E1_Ubiquitin_72,Uba1,E1_Ubiquitin,P0CG63,0.714412,NO,72,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.184,-2.599,1.415,,0.077,,B,0.16,-0.1,,,,HBH,-1.08733,0.18783,0.00129853,0.714412 kka2_1:4_Q26N,kka2_1:4_26,Kka2,kka2_1:4,P00552,0.714466,NO,26,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.18,-3.808,1.628,,0.448,E,B,0.4,0.44,5.022,,92.05,HPP,-2.11167,0.168804,0.00708962,0.714466 beta-lactamase_0_G114E,beta-lactamase_0_114,TEM-1,beta-lactamase_0,P62593,0.71451,NO,114,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.094,-3.605,2.511,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.0500837,0.00224919,0.71451 kka2_1:1_G74A,kka2_1:1_74,Kka2,kka2_1:1,P00552,0.714521,NO,74,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.18,-3.17,1.99,,0.621,T,l,0.75,0.2,15.356,15.356,64.39,POH,-1.91667,0.520039,0.00587035,0.714521 beta-lactamase_156_W288E,beta-lactamase_156_288,TEM-1,beta-lactamase_156,P62593,0.714593,NO,288,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,,,,,,,,,,,,,BHO,,0.111618,,0.714593 kka2_1:2_D227N,kka2_1:2_227,Kka2,kka2_1:2,P00552,0.714601,NO,227,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.758,-3.296,1.538,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.295029,0.00745029,0.714601 beta-lactamase_0_E35K,beta-lactamase_0_35,TEM-1,beta-lactamase_0,P62593,0.714604,NO,35,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-0.869,-3.075,2.206,,0.15,H,A,1.04,0.21,0.664,,46.85,HAA,-1.88667,0.0500837,0.00174441,0.714604 kka2_1:1_K50T,kka2_1:1_50,Kka2,kka2_1:1,P00552,0.714663,NO,50,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-0.833,-3.473,2.64,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.520039,0.00138626,0.714663 kka2_1:4_L92P,kka2_1:4_92,Kka2,kka2_1:4,P00552,0.714681,NO,92,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.893,-4.134,3.241,,0.007,E,B,0.55,-0.19,1.447,,63.26,HHH,-0.962,0.168804,0.00307177,0.714681 kka2_1:2_R121S,kka2_1:2_121,Kka2,kka2_1:2,P00552,0.714733,NO,121,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.552,-2.658,1.106,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.295029,0.00523326,0.714733 beta-lactamase_0_L197H,beta-lactamase_0_197,TEM-1,beta-lactamase_0,P62593,0.714804,NO,197,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.853,-4.903,4.05,,0.007,S,B,0.55,0.33,1.087,,60.14,HHP,-1.833,0.0500837,0.00144602,0.714804 kka2_1:1_V46L,kka2_1:1_46,Kka2,kka2_1:1,P00552,0.714851,NO,46,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-2.62,-3.558,0.938,,0.192,.,B,0.44,-1.12,20.149,20.149,92.05,OHH,-1.88633,0.520039,0.00631301,0.714851 beta-lactamase_156_D161R,beta-lactamase_156_161,TEM-1,beta-lactamase_156,P62593,0.714912,NO,161,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.891,-3.902,3.011,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.111618,0.000897697,0.714912 beta-lactamase_39_P65D,beta-lactamase_39_65,TEM-1,beta-lactamase_39,P62593,0.714966,NO,65,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.894,-3.578,2.684,,0.098,E,B,0.52,-0.62,0.623,,40.56,HOH,-1.03233,0.0495842,0.00152776,0.714966 beta-lactamase_0_H287M,beta-lactamase_0_287,TEM-1,beta-lactamase_0,P62593,0.715005,NO,287,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,,,,,,,,,,,,,BBH,-1.111,0.0500837,,0.715005 beta-lactamase_0_T139P,beta-lactamase_0_139,TEM-1,beta-lactamase_0,P62593,0.715009,NO,139,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.901,-3.919,2.018,,0.216,H,A,0.22,0.39,0.421,,77.62,PPH,-2.04667,0.0500837,0.00441837,0.715009 Pab1_G150C,Pab1_150,Pab1,Pab1,P04147,0.715029,NO,150,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.809,-4.904,4.095,,0.287,S,b,0.23,0.53,,,,HOA,-1.45233,0.175299,0.000323835,0.715029 beta-lactamase_2500_V106W,beta-lactamase_2500_106,TEM-1,beta-lactamase_2500,P62593,0.71503,NO,106,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.218,-5.22,4.002,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.361275,0.00304168,0.71503 kka2_1:4_I254E,kka2_1:4_254,Kka2,kka2_1:4,P00552,0.71505,NO,254,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.933,-3.931,1.998,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.168804,0.0132375,0.71505 kka2_1:8_L67P,kka2_1:8_67,Kka2,kka2_1:8,P00552,0.715071,NO,67,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.741,-4.133,3.392,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.100394,0.00102787,0.715071 kka2_1:8_L67P,kka2_1:8_67,Kka2,kka2_1:8,P00552,0.715071,NO,67,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.741,-4.133,3.392,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.100394,0.00102787,0.715071 kka2_1:4_K112R,kka2_1:4_112,Kka2,kka2_1:4,P00552,0.715159,NO,112,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-2.491,-2.2,-0.291,,0.076,H,A,2.34,-1.37,0.39,,56.06,ABH,-2.00133,0.168804,0.00645389,0.715159 kka2_1:1_P98T,kka2_1:1_98,Kka2,kka2_1:1,P00552,0.715172,NO,98,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.526,-2.967,1.441,,0.391,S,B,0.52,-0.65,1.521,,63.26,HOO,-1.19167,0.520039,0.00622754,0.715172 beta-lactamase_2500_W288Y,beta-lactamase_2500_288,TEM-1,beta-lactamase_2500,P62593,0.715185,NO,288,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,,,,,,,,,,,,,BHO,,0.361275,,0.715185 PSD95pdz3_E331R,PSD95pdz3_331,PSD95pdz3,PSD95pdz3,P31016,0.715207,NO,331,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.404,-3.165,1.761,5.86289,,,,,51.8889,,,,OAA,-1.22533,0.0758425,0.000950134,0.715207 kka2_1:2_T225D,kka2_1:2_225,Kka2,kka2_1:2,P00552,0.715255,NO,225,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.393,-3.922,1.529,,0.036,H,A,0.22,-1.22,4.554,,63.64,HPB,-1.58733,0.295029,0.0113598,0.715255 kka2_1:8_L241F,kka2_1:8_241,Kka2,kka2_1:8,P00552,0.715304,NO,241,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.158,-1.703,0.545,,0.08,H,A,1.59,-0.82,1.136,,63.26,HHH,-1.58533,0.100394,0.0117299,0.715304 kka2_1:8_L241F,kka2_1:8_241,Kka2,kka2_1:8,P00552,0.715304,NO,241,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.158,-1.703,0.545,,0.08,H,A,1.59,-0.82,1.136,,63.26,HHH,-1.58533,0.100394,0.0117299,0.715304 kka2_1:1_R121S,kka2_1:1_121,Kka2,kka2_1:1,P00552,0.715354,NO,121,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.552,-2.658,1.106,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.520039,0.00523326,0.715354 kka2_1:2_C31G,kka2_1:2_31,Kka2,kka2_1:2,P00552,0.715589,NO,31,C,G,CG,Special,Special,5.07,3.29388,-1.77612,159,121,75,-46,108.5,60.1,-48.4,-2.246,-3.573,1.327,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.295029,0.00681582,0.715589 beta-lactamase_625_E35G,beta-lactamase_625_35,TEM-1,beta-lactamase_625,P62593,0.715633,NO,35,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-0.869,-3.356,2.487,,0.15,H,A,1.04,0.21,0.664,,46.85,HAA,-1.88667,0.213352,0.00174441,0.715633 beta-lactamase_0_D48P,beta-lactamase_0_48,TEM-1,beta-lactamase_0,P62593,0.715756,NO,48,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.101,-3.766,2.665,,0.189,E,B,0.75,0.21,17.825,17.825,50.35,HAH,-1.62467,0.0500837,0.0027273,0.715756 gb1_E282D,gb1_282,gb1,gb1,P06654,0.715816,NO,282,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.318,-2.743,1.425,,,,,,,1.075,,35.71,PAO,-1.573,0.177985,0.00209643,0.715816 gb1_K254V,gb1_254,gb1,gb1,P06654,0.715816,NO,254,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.748,-3.394,1.646,,,,,,,1.793,,37.28,ABH,-2.195,0.177985,0.00622711,0.715816 WW_domain_T198N,WW_domain_198,Yap65,WW_domain,P46937,0.71585,NO,198,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.451,-3.547,2.096,5.14348,,,,,,3.158,,70.04,PPH,-1.513,0.153962,0.00224534,0.71585 PSD95pdz3_A376E,PSD95pdz3_376,PSD95pdz3,PSD95pdz3,P31016,0.715899,NO,376,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.307,-3.122,1.815,4.72134,,,,,17.108,,,,HHH,-1.49567,0.0758425,0.000341232,0.715899 kka2_1:1_P76L,kka2_1:1_76,Kka2,kka2_1:1,P00552,0.715908,NO,76,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.449,-2.705,1.256,,0.331,.,B,0.52,-0.41,0.345,,63.64,HOO,-1.662,0.520039,0.00625685,0.715908 kka2_1:4_A229L,kka2_1:4_229,Kka2,kka2_1:4,P00552,0.715941,NO,229,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.739,-3.501,1.762,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.168804,0.00942138,0.715941 kka2_1:1_H8E,kka2_1:1_8,Kka2,kka2_1:1,P00552,0.715942,NO,8,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-2.759,-3.378,0.619,,,,,,,16.971,16.971,71.59,HBH,-2.25467,0.520039,0.00256422,0.715942 beta-lactamase_D174A,beta-lactamase_174,TEM-1,beta-lactamase,P62593,0.715944,NO,174,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.738,-3.303,2.565,5.44133,0.238,,B,1.22,-0.1,,,,PAA,-1.91233,0.221079,0.00125633,0.715944 beta-lactamase_L167G,beta-lactamase_167,TEM-1,beta-lactamase,P62593,0.715963,NO,167,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.138,-3.694,2.556,5.13111,0.015,G,A,0.08,-0.63,0.4,,64.69,AHP,-1.30767,0.221079,0.00303566,0.715963 kka2_1:8_C192F,kka2_1:8_192,Kka2,kka2_1:8,P00552,0.715968,NO,192,C,F,CF,Special,Hydrophobic,5.07,3.32051,-1.74949,205,121,165,44,108.5,189.9,81.4,-1.067,-4.014,2.947,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.100394,0.00485428,0.715968 kka2_1:8_C192F,kka2_1:8_192,Kka2,kka2_1:8,P00552,0.715968,NO,192,C,F,CF,Special,Hydrophobic,5.07,3.32051,-1.74949,205,121,165,44,108.5,189.9,81.4,-1.067,-4.014,2.947,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.100394,0.00485428,0.715968 PSD95pdz3_I336D,PSD95pdz3_336,PSD95pdz3,PSD95pdz3,P31016,0.716055,NO,336,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.63,-3.6,1.97,5.11321,,,,,13.6363,,,,OHH,-1.38733,0.0758425,0.000887923,0.716055 beta-lactamase_G76W,beta-lactamase_76,TEM-1,beta-lactamase,P62593,0.71608,NO,76,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.189,-5.284,4.095,4.73862,,H,A,2.05,-0.67,3.059,,67.83,OOH,-1.22267,0.221079,0.00476637,0.71608 kka2_1:1_I246R,kka2_1:1_246,Kka2,kka2_1:1,P00552,0.716146,NO,246,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-2.008,-3.32,1.312,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.520039,0.0139479,0.716146 kka2_1:2_H135D,kka2_1:2_135,Kka2,kka2_1:2,P00552,0.716173,NO,135,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-1.331,-3.636,2.305,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.295029,0.00532566,0.716173 kka2_1:8_A237E,kka2_1:8_237,Kka2,kka2_1:8,P00552,0.716202,NO,237,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.12,-3.758,1.638,,0.068,H,A,0.46,-0.71,0.449,,92.05,HHA,-2.10433,0.100394,0.012257,0.716202 kka2_1:8_A237E,kka2_1:8_237,Kka2,kka2_1:8,P00552,0.716202,NO,237,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.12,-3.758,1.638,,0.068,H,A,0.46,-0.71,0.449,,92.05,HHA,-2.10433,0.100394,0.012257,0.716202 beta-lactamase_2500_N168S,beta-lactamase_2500_168,TEM-1,beta-lactamase_2500,P62593,0.716277,NO,168,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-1.029,-2.37,1.341,,0.113,G,A,0.61,-0.4,2.9,,44.41,HPA,-1.13233,0.361275,0.00288667,0.716277 beta-lactamase_A230L,beta-lactamase_230,TEM-1,beta-lactamase,P62593,0.716341,NO,230,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.154,-3.416,2.262,4.54336,0.01,E,B,0.75,-1.17,1.97,,50,HHA,-1.079,0.221079,0.00516841,0.716341 beta-lactamase_L197S,beta-lactamase_197,TEM-1,beta-lactamase,P62593,0.716341,NO,197,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.853,-3.532,2.679,5.19172,0.007,S,B,1.3,0.33,1.756,,60.14,HHP,-1.833,0.221079,0.00144602,0.716341 beta-lactamase_0_E35I,beta-lactamase_0_35,TEM-1,beta-lactamase_0,P62593,0.71639,NO,35,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-0.869,-4.036,3.167,,0.15,H,A,1.04,0.21,0.664,,46.85,HAA,-1.88667,0.0500837,0.00174441,0.71639 beta-lactamase_P249G,beta-lactamase_249,TEM-1,beta-lactamase,P62593,0.716413,NO,249,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.312,-2.663,1.351,5.10655,0.256,S,B,0.99,0.04,0.479,,72.73,OOA,-1.81367,0.221079,0.00220169,0.716413 beta-lactamase_0_K32D,beta-lactamase_0_32,TEM-1,beta-lactamase_0,P62593,0.716586,NO,32,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.984,-2.882,0.898,,0.563,H,A,2.34,0.34,0.418,,73.08,HBA,-2.04233,0.0500837,0.00401283,0.716586 beta-lactamase_625_L146Q,beta-lactamase_625_146,TEM-1,beta-lactamase_625,P62593,0.716606,NO,146,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.462,-4.29,2.828,,0.007,H,A,0.55,-0.56,2.16,,64.69,AHP,-1.656,0.213352,0.00474542,0.716606 kka2_1:1_G213C,kka2_1:1_213,Kka2,kka2_1:1,P00552,0.716684,NO,213,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.596,-5.115,4.519,,,E,b,0.29,-0.4,,,,HOH,-0.920333,0.520039,0.00187654,0.716684 beta-lactamase_0_L47R,beta-lactamase_0_47,TEM-1,beta-lactamase_0,P62593,0.716714,NO,47,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.876,-2.668,0.792,,0.007,E,B,0.55,0.2,1.024,,67.83,AHA,-1.639,0.0500837,0.00439844,0.716714 gb1_E282M,gb1_282,gb1,gb1,P06654,0.716754,NO,282,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.318,-4.475,3.157,,,,,,,1.075,,35.71,PAO,-1.573,0.177985,0.00209643,0.716754 gb1_Y259V,gb1_259,gb1,gb1,P06654,0.716754,NO,259,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-1.78,-3.264,1.484,,,,,,,0.131,,11.83,PHH,-1.787,0.177985,0.00464313,0.716754 kka2_1:4_P12F,kka2_1:4_12,Kka2,kka2_1:4,P00552,0.716798,NO,12,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.853,-4.467,3.614,,,,B,0.52,1.25,0.843,,48.11,POH,-1.80767,0.168804,0.00500011,0.716798 kka2_1:1_L53Q,kka2_1:1_53,Kka2,kka2_1:1,P00552,0.716916,NO,53,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-2.681,-2.601,-0.08,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.520039,0.00671168,0.716916 kka2_1:1_N58D,kka2_1:1_58,Kka2,kka2_1:1,P00552,0.716983,NO,58,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-2.641,-2.6,-0.041,,0.131,S,A,0.61,0.72,30.755,30.755,71.59,HPA,-1.83033,0.520039,0.00793425,0.716983 kka2_1:1_A247K,kka2_1:1_247,Kka2,kka2_1:1,P00552,0.717005,NO,247,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.459,-3.008,0.549,,1.01,S,A,0.46,0.65,7.731,7.731,92.05,HHH,-2.197,0.520039,0.0102428,0.717005 beta-lactamase_V214P,beta-lactamase_214,TEM-1,beta-lactamase,P62593,0.71701,NO,214,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.299,-3.919,2.62,5.74008,0.375,S,A,1.19,-0.44,1.899,,74.48,BHH,-1.53733,0.221079,0.00628442,0.71701 beta-lactamase_0_H151G,beta-lactamase_0_151,TEM-1,beta-lactamase_0,P62593,0.717114,NO,151,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-2.96,-2.515,-0.445,,0.594,H,A,0.17,0.1,9.375,,77.62,HBP,-2.34767,0.0500837,0.00216946,0.717114 kka2_1:1_L94M,kka2_1:1_94,Kka2,kka2_1:1,P00552,0.717183,NO,94,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.618,-1.512,-0.106,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.520039,0.00520888,0.717183 beta-lactamase_I93T,beta-lactamase_93,TEM-1,beta-lactamase,P62593,0.71719,NO,93,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.401,-2.729,1.328,5.74695,0.128,E,B,0.77,0.44,1.757,,67.83,BHB,-1.873,0.221079,0.00527066,0.71719 beta-lactamase_2500_R162Q,beta-lactamase_2500_162,TEM-1,beta-lactamase_2500,P62593,0.717191,NO,162,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.016,-3.59,2.574,,0.124,S,B,1.2,-0.37,6.199,,64.69,ABH,-1.25,0.361275,0.000561334,0.717191 PSD95pdz3_I316H,PSD95pdz3_316,PSD95pdz3,PSD95pdz3,P31016,0.717232,NO,316,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.63,-4.587,2.957,5.46166,,,,,19.005,,,,HHB,-1.62733,0.0758425,0.00112762,0.717232 beta-lactamase_2500_C75I,beta-lactamase_2500_75,TEM-1,beta-lactamase_2500,P62593,0.717233,NO,75,C,I,CI,Special,Hydrophobic,5.07,6.02,0.95,198,121,131,10,108.5,166.7,58.2,-1.245,-3.708,2.463,,,H,A,0.46,-0.87,0.844,,50,HOO,-1.24333,0.361275,0.0034616,0.717233 PSD95pdz3_G330C,PSD95pdz3_330,PSD95pdz3,PSD95pdz3,P31016,0.717251,NO,330,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.008,-4.769,3.761,4.68351,,,,,31.405,,,,OOA,-1.14,0.0758425,0.000962386,0.717251 beta-lactamase_E87G,beta-lactamase_87,TEM-1,beta-lactamase,P62593,0.717283,NO,87,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.421,-3.541,2.12,5.41929,0.048,,B,0.52,0.92,1.754,,64.69,PAP,-1.969,0.221079,0.00337888,0.717283 beta-lactamase_625_S51C,beta-lactamase_625_51,TEM-1,beta-lactamase_625,P62593,0.717323,NO,51,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.526,-4.878,3.352,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.213352,0.00504821,0.717323 beta-lactamase_I11R,beta-lactamase_11,TEM-1,beta-lactamase,P62593,0.71737,NO,11,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.745,-4.105,2.36,,,,,,,3.135,,66.08,HHO,-1.79467,0.221079,0.00261325,0.71737 kka2_1:1_R18H,kka2_1:1_18,Kka2,kka2_1:1,P00552,0.71739,NO,18,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.055,-3.59,1.535,,0.474,T,A,1.2,0.54,11.422,11.422,71.59,ABH,-1.821,0.520039,0.00724065,0.71739 beta-lactamase_0_R63N,beta-lactamase_0_63,TEM-1,beta-lactamase_0,P62593,0.717414,NO,63,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-0.943,-3.531,2.588,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.0500837,0.00126938,0.717414 kka2_1:4_G99A,kka2_1:4_99,Kka2,kka2_1:4,P00552,0.717423,NO,99,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.596,-2.881,2.285,,0.368,S,g,0.29,-0.87,,,,OOP,-1.63067,0.168804,0.00186055,0.717423 kka2_1:1_R44K,kka2_1:1_44,Kka2,kka2_1:1,P00552,0.717492,NO,44,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.062,-2.763,0.701,,0.487,S,B,1.2,-0.35,2.717,,71.59,OBO,-1.80767,0.520039,0.00745043,0.717492 kka2_1:8_V97N,kka2_1:8_97,Kka2,kka2_1:8,P00552,0.717525,NO,97,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.453,-4.261,2.808,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.100394,0.00737869,0.717525 kka2_1:8_V97N,kka2_1:8_97,Kka2,kka2_1:8,P00552,0.717525,NO,97,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.453,-4.261,2.808,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.100394,0.00737869,0.717525 beta-lactamase_0_V259H,beta-lactamase_0_259,TEM-1,beta-lactamase_0,P62593,0.717574,NO,259,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.0500837,0.0070773,0.717574 kka2_1:1_E199C,kka2_1:1_199,Kka2,kka2_1:1,P00552,0.717596,NO,199,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.234,-3.64,1.406,,0.508,E,B,1.04,-0.43,3.012,,65.53,HAP,-2.133,0.520039,0.00854122,0.717596 Pab1_S155I,Pab1_155,Pab1,Pab1,P04147,0.717599,NO,155,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.039,-3.304,1.265,,,,,,,,,,PPB,-1.42267,0.175299,0.00208179,0.717599 kka2_1:4_F264S,kka2_1:4_264,Kka2,kka2_1:4,P00552,0.717697,NO,264,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.02,-3.713,2.693,,0.296,,?,1.62,0.02,1.93,,71.59,HHO,-0.9655,0.168804,,0.717697 kka2_1:2_A56W,kka2_1:2_56,Kka2,kka2_1:2,P00552,0.717704,NO,56,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.083,-5.608,3.525,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.295029,0.00717715,0.717704 kka2_1:1_E63D,kka2_1:1_63,Kka2,kka2_1:1,P00552,0.71771,NO,63,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-0.762,-2.822,2.06,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.520039,0.00118399,0.71771 Ubiquitin_F4W,Ubiquitin_4,Uba1,Ubiquitin,P0CG48,0.717742,NO,4,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.534,-4.621,3.087,4.77459,0.059,E,B,,-0.46,,,,HHH,-1.504,0.205827,0.000805043,0.717742 Ubiquitin_G35D,Ubiquitin_35,Uba1,Ubiquitin,P0CG48,0.717742,NO,35,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.171,-3.497,2.326,4.96213,0.713,,L,,0.2,,,,AOH,-1.314,0.205827,0.000648878,0.717742 Ubiquitin_L8M,Ubiquitin_8,Uba1,Ubiquitin,P0CG48,0.717742,NO,8,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.723,-3.156,1.433,5.28016,0.664,T,A,0.08,-0.34,0.664,,29.05,PHP,-1.51567,0.205827,0.000726165,0.717742 Ubiquitin_T66I,Ubiquitin_66,Uba1,Ubiquitin,P0CG48,0.717742,NO,66,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.58,-2.704,1.124,5.02702,0.46,E,B,0.8,-0.81,28.36,28.36,39.71,PPH,-1.51667,0.205827,0.000598414,0.717742 beta-lactamase_0_Y95D,beta-lactamase_0_95,TEM-1,beta-lactamase_0,P62593,0.717774,NO,95,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-1.715,-4.078,2.363,,0.122,,b,0.21,-0.37,2.914,,77.62,BHP,-2.16167,0.0500837,0.00479449,0.717774 kka2_1:1_G164C,kka2_1:1_164,Kka2,kka2_1:1,P00552,0.717796,NO,164,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.869,-5.135,4.266,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.520039,0.00442091,0.717796 kka2_1:8_G30C,kka2_1:8_30,Kka2,kka2_1:8,P00552,0.717797,NO,30,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.596,-5.115,4.519,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.100394,0.00159208,0.717797 kka2_1:8_G30C,kka2_1:8_30,Kka2,kka2_1:8,P00552,0.717797,NO,30,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.596,-5.115,4.519,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.100394,0.00159208,0.717797 beta-lactamase_L137Q,beta-lactamase_137,TEM-1,beta-lactamase,P62593,0.717804,NO,137,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.03,-4.147,3.117,5.20117,,H,A,1.07,-0.38,0.674,,42.31,HHP,-1.58933,0.221079,0.00278599,0.717804 beta-lactamase_39_N130E,beta-lactamase_39_130,TEM-1,beta-lactamase_39,P62593,0.717831,NO,130,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-0.798,-3.215,2.417,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.0495842,0.000683376,0.717831 beta-lactamase_2500_W208M,beta-lactamase_2500_208,TEM-1,beta-lactamase_2500,P62593,0.71784,NO,208,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-0.818,-4.48,3.662,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.361275,0.00126609,0.71784 PSD95pdz3_L367K,PSD95pdz3_367,PSD95pdz3,PSD95pdz3,P31016,0.717943,NO,367,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.347,-3.364,2.017,5.47696,,,,,17.0063,,,,AHB,-1.39767,0.0758425,0.000466436,0.717943 beta-lactamase_0_L197D,beta-lactamase_0_197,TEM-1,beta-lactamase_0,P62593,0.71797,NO,197,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.853,-4.107,3.254,,0.007,S,B,0.55,0.33,1.087,,60.14,HHP,-1.833,0.0500837,0.00144602,0.71797 beta-lactamase_625_D83K,beta-lactamase_625_83,TEM-1,beta-lactamase_625,P62593,0.717978,NO,83,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.066,-3.429,2.363,,0.354,H,A,0.75,0.22,0.239,,48.95,HAH,-1.34733,0.213352,0.00205968,0.717978 beta-lactamase_L10R,beta-lactamase_10,TEM-1,beta-lactamase,P62593,0.717984,NO,10,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.623,-4.021,2.398,,,,,,,2.467,,65.38,HHH,-1.83833,0.221079,0.00296968,0.717984 beta-lactamase_625_C121G,beta-lactamase_625_121,TEM-1,beta-lactamase_625,P62593,0.718008,NO,121,C,G,CG,Special,Special,5.07,3.29388,-1.77612,159,121,75,-46,108.5,60.1,-48.4,-0.953,-3.581,2.628,,,H,A,0.46,-0.81,1.143,,63.29,HOP,-1.46767,0.213352,0.000744322,0.718008 beta-lactamase_2500_G154S,beta-lactamase_2500_154,TEM-1,beta-lactamase_2500,P62593,0.718039,NO,154,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.823,-3.197,2.374,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.361275,0.00180205,0.718039 beta-lactamase_156_N130T,beta-lactamase_156_130,TEM-1,beta-lactamase_156,P62593,0.718094,NO,130,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-0.798,-3.196,2.398,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.111618,0.000683376,0.718094 beta-lactamase_0_K254G,beta-lactamase_0_254,TEM-1,beta-lactamase_0,P62593,0.718095,NO,254,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.0500837,0.00369,0.718095 kka2_1:1_R143A,kka2_1:1_143,Kka2,kka2_1:1,P00552,0.718113,NO,143,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.525,-2.1,-0.425,,0.325,H,A,0.16,1.22,3.6,,65.53,ABH,-1.86833,0.520039,0.00662247,0.718113 kka2_1:2_C209R,kka2_1:2_209,Kka2,kka2_1:2,P00552,0.718127,NO,209,C,R,CR,Special,PositiveCharge,5.07,6.34148,1.27148,180,121,174,53,108.5,173.4,64.9,-0.906,-4.184,3.278,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.295029,0.00260862,0.718127 kka2_1:8_L241W,kka2_1:8_241,Kka2,kka2_1:8,P00552,0.718224,NO,241,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.158,-4.909,3.751,,0.08,H,A,1.59,-0.82,1.136,,63.26,HHH,-1.58533,0.100394,0.0117299,0.718224 kka2_1:8_L241W,kka2_1:8_241,Kka2,kka2_1:8,P00552,0.718224,NO,241,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.158,-4.909,3.751,,0.08,H,A,1.59,-0.82,1.136,,63.26,HHH,-1.58533,0.100394,0.0117299,0.718224 PSD95pdz3_P346D,PSD95pdz3_346,PSD95pdz3,PSD95pdz3,P31016,0.718254,NO,346,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.236,-3.15,1.914,5.02406,,,,,14.6629,,,,OOH,-1.18367,0.0758425,0.000758563,0.718254 beta-lactamase_Q204G,beta-lactamase_204,TEM-1,beta-lactamase,P62593,0.718301,NO,204,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-1.382,-3.474,2.092,5.46394,0.204,H,A,0.12,0.09,1.707,,66.08,PPH,-1.49067,0.221079,0.00364106,0.718301 WW_domain_T198G,WW_domain_198,Yap65,WW_domain,P46937,0.718329,NO,198,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.451,-3.202,1.751,5.14348,,,,,,3.158,,70.04,PPH,-1.513,0.153962,0.00224534,0.718329 Pab1_S155F,Pab1_155,Pab1,Pab1,P04147,0.718386,NO,155,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.039,-3.955,1.916,,,,,,,,,,PPB,-1.42267,0.175299,0.00208179,0.718386 beta-lactamase_P143I,beta-lactamase_143,TEM-1,beta-lactamase,P62593,0.718449,NO,143,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.967,-2.787,1.82,5.16366,0.075,H,A,0.99,-0.37,0.479,,66.78,OOB,-1.354,0.221079,0.00114551,0.718449 beta-lactamase_L49H,beta-lactamase_49,TEM-1,beta-lactamase,P62593,0.718675,NO,49,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.897,-4.794,2.897,5.86005,0.131,T,A,1.3,0.04,3.112,,64.69,AHP,-1.99233,0.221079,0.00401477,0.718675 kka2_1:2_T51A,kka2_1:2_51,Kka2,kka2_1:2,P00552,0.718699,NO,51,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.199,-2.346,0.147,,0.05,E,B,0.22,-0.05,13.165,13.165,63.64,BPA,-1.76767,0.295029,0.00628861,0.718699 beta-lactamase_2500_L137F,beta-lactamase_2500_137,TEM-1,beta-lactamase_2500,P62593,0.718746,NO,137,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.03,-3.682,2.652,,,H,A,0.55,-0.38,0.769,,42.31,HHP,-1.58933,0.361275,0.00278599,0.718746 beta-lactamase_0_H287P,beta-lactamase_0_287,TEM-1,beta-lactamase_0,P62593,0.718757,NO,287,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,,,,,,,,,,,,,BBH,-1.111,0.0500837,,0.718757 beta-lactamase_0_G43C,beta-lactamase_0_43,TEM-1,beta-lactamase_0,P62593,0.718794,NO,43,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.62,-5.087,4.467,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.0500837,0.00120151,0.718794 kka2_1:4_V97R,kka2_1:4_97,Kka2,kka2_1:4,P00552,0.718804,NO,97,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.453,-4.167,2.714,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.168804,0.00737869,0.718804 beta-lactamase_0_T27W,beta-lactamase_0_27,TEM-1,beta-lactamase_0,P62593,0.718813,NO,27,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.905,-5.314,3.409,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.0500837,0.00306559,0.718813 beta-lactamase_I256A,beta-lactamase_256,TEM-1,beta-lactamase,P62593,0.718907,NO,256,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.621,-2.664,1.043,5.3196,,E,B,1,-0.84,1.615,,73.08,BHH,-1.80667,0.221079,0.00710634,0.718907 kka2_1:2_S40I,kka2_1:2_40,Kka2,kka2_1:2,P00552,0.71894,NO,40,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.645,-4.1,1.455,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.295029,0.00693477,0.71894 beta-lactamase_0_L197N,beta-lactamase_0_197,TEM-1,beta-lactamase_0,P62593,0.718984,NO,197,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.853,-4.12,3.267,,0.007,S,B,0.55,0.33,1.087,,60.14,HHP,-1.833,0.0500837,0.00144602,0.718984 kka2_1:2_L241P,kka2_1:2_241,Kka2,kka2_1:2,P00552,0.719038,NO,241,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.158,-4.275,3.117,,0.08,H,A,0.55,-0.82,1.598,,63.26,HHH,-1.58533,0.295029,0.0117299,0.719038 kka2_1:4_D227Y,kka2_1:4_227,Kka2,kka2_1:4,P00552,0.719104,NO,227,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.758,-4.295,2.537,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.168804,0.00745029,0.719104 kka2_1:2_D118Y,kka2_1:2_118,Kka2,kka2_1:2,P00552,0.719125,NO,118,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.07,-4.383,2.313,,0.61,H,A,0.75,-0.05,2.237,,64.39,HAH,-1.32367,0.295029,0.0067852,0.719125 kka2_1:1_I115K,kka2_1:1_115,Kka2,kka2_1:1,P00552,0.719163,NO,115,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.606,-3.902,2.296,,0.105,H,A,0.48,-1.18,0.878,,65.53,PHH,-2.205,0.520039,0.00836567,0.719163 beta-lactamase_156_R189P,beta-lactamase_156_189,TEM-1,beta-lactamase_156,P62593,0.719195,NO,189,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.844,-3.964,2.12,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.111618,0.0050699,0.719195 beta-lactamase_F22P,beta-lactamase_22,TEM-1,beta-lactamase,P62593,0.719216,NO,22,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-2.676,-4.088,1.412,,,,,,,1.616,,73.08,HHH,-2.03233,0.221079,0.00262842,0.719216 kka2_1:4_D220A,kka2_1:4_220,Kka2,kka2_1:4,P00552,0.71924,NO,220,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.787,-3.298,2.511,,,H,A,0.75,-1.14,1.237,,46.59,PAH,-1.152,0.168804,0.00158066,0.71924 PSD95pdz3_I327L,PSD95pdz3_327,PSD95pdz3,PSD95pdz3,P31016,0.71927,NO,327,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.63,-2.14,0.51,5.7413,,,,,14.0388,,,,PHH,-1.50167,0.0758425,0.000998774,0.71927 beta-lactamase_D83T,beta-lactamase_83,TEM-1,beta-lactamase,P62593,0.719279,NO,83,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.066,-3.464,2.398,5.40616,0.354,H,A,1.33,0.22,0.861,,48.95,HAH,-1.34733,0.221079,0.00205968,0.719279 Pab1_I196Y,Pab1_196,Pab1,Pab1,P04147,0.719305,NO,196,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.795,-3.83,2.035,,,,,,,2.013,,80.59,AHH,-1.44667,0.175299,0.0016933,0.719305 kka2_1:2_E17C,kka2_1:2_17,Kka2,kka2_1:2,P00552,0.719334,NO,17,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.154,-5.239,3.085,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.295029,0.00688738,0.719334 beta-lactamase_156_L120Q,beta-lactamase_156_120,TEM-1,beta-lactamase_156,P62593,0.719352,NO,120,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.044,-4.124,3.08,,,H,A,0.55,-1.13,7.813,,64.69,AHO,-1.13633,0.111618,0.00143563,0.719352 beta-lactamase_0_A183K,beta-lactamase_0_183,TEM-1,beta-lactamase_0,P62593,0.719417,NO,183,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.231,-3.508,2.277,,0.155,H,A,0.46,-0.91,1.48,,77.62,HHH,-1.53367,0.0500837,0.00296631,0.719417 beta-lactamase_39_L284R,beta-lactamase_39_284,TEM-1,beta-lactamase_39,P62593,0.719459,NO,284,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.0495842,0.0686156,0.719459 beta-lactamase_2500_L192Y,beta-lactamase_2500_192,TEM-1,beta-lactamase_2500,P62593,0.719471,NO,192,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.254,-3.913,2.659,,0.095,H,A,0.55,0.35,1.902,,60.14,HHP,-1.41833,0.361275,0.00558728,0.719471 beta-lactamase_2500_F228V,beta-lactamase_2500_228,TEM-1,beta-lactamase_2500,P62593,0.719482,NO,228,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-2.342,-2.889,0.547,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.361275,0.0046669,0.719482 kka2_1:1_A144E,kka2_1:1_144,Kka2,kka2_1:1,P00552,0.719488,NO,144,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.859,-3.551,2.692,,,H,A,0.46,0.21,0.842,,52.65,BHB,-1.72933,0.520039,0.00231095,0.719488 kka2_1:2_E230W,kka2_1:2_230,Kka2,kka2_1:2,P00552,0.719498,NO,230,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.672,-5.201,2.529,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.295029,0.00920051,0.719498 kka2_1:8_W69R,kka2_1:8_69,Kka2,kka2_1:8,P00552,0.7195,NO,69,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-0.859,-4.184,3.325,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.100394,0.0012874,0.7195 kka2_1:8_W69R,kka2_1:8_69,Kka2,kka2_1:8,P00552,0.7195,NO,69,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-0.859,-4.184,3.325,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.100394,0.0012874,0.7195 kka2_1:1_C31F,kka2_1:1_31,Kka2,kka2_1:1,P00552,0.719531,NO,31,C,F,CF,Special,Hydrophobic,5.07,3.32051,-1.74949,205,121,165,44,108.5,189.9,81.4,-2.246,-4.376,2.13,,1.152,S,b,0.46,4.16,8.272,,63.26,OOP,-1.21533,0.520039,0.00681582,0.719531 beta-lactamase_2500_G154H,beta-lactamase_2500_154,TEM-1,beta-lactamase_2500,P62593,0.719534,NO,154,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.823,-4.704,3.881,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.361275,0.00180205,0.719534 Pab1_D160P,Pab1_160,Pab1,Pab1,P04147,0.719557,NO,160,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.985,-3.472,2.487,,0.396,B,B,,1.12,,,,PAA,-1.30133,0.175299,0.000311977,0.719557 beta-lactamase_G154L,beta-lactamase_154,TEM-1,beta-lactamase,P62593,0.719609,NO,154,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.823,-3.779,2.956,5.40944,0.54,T,l,0.77,-0.56,2.283,,64.69,HOA,-1.635,0.221079,0.00180205,0.719609 beta-lactamase_156_D83F,beta-lactamase_156_83,TEM-1,beta-lactamase_156,P62593,0.719694,NO,83,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.066,-4.344,3.278,,0.354,H,A,0.75,0.22,1.281,,48.95,HAH,-1.34733,0.111618,0.00205968,0.719694 beta-lactamase_0_P224H,beta-lactamase_0_224,TEM-1,beta-lactamase_0,P62593,0.719729,NO,224,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.893,-4.649,3.756,,0.383,,B,0.52,-0.3,3.587,,74.48,HOH,-1.26433,0.0500837,0.00189564,0.719729 beta-lactamase_V21W,beta-lactamase_21,TEM-1,beta-lactamase,P62593,0.719729,NO,21,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.873,-5.307,3.434,,,,,,,0.688,,93.01,OHH,-2.09633,0.221079,0.0028612,0.719729 kka2_1:8_A191N,kka2_1:8_191,Kka2,kka2_1:8,P00552,0.719802,NO,191,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.831,-3.96,3.129,,,,b,1.04,-0.94,1.306,,50,AHO,-0.868667,0.100394,0.00338807,0.719802 kka2_1:8_A191N,kka2_1:8_191,Kka2,kka2_1:8,P00552,0.719802,NO,191,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.831,-3.96,3.129,,,,b,1.04,-0.94,1.306,,50,AHO,-0.868667,0.100394,0.00338807,0.719802 kka2_1:1_W69R,kka2_1:1_69,Kka2,kka2_1:1,P00552,0.719815,NO,69,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-0.859,-4.184,3.325,,0.164,H,A,0.47,0.15,5.074,,38.64,PHH,-1.49967,0.520039,0.0012874,0.719815 kka2_1:8_V198W,kka2_1:8_198,Kka2,kka2_1:8,P00552,0.719847,NO,198,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.719,-5.441,3.722,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.100394,0.00835002,0.719847 kka2_1:8_V198W,kka2_1:8_198,Kka2,kka2_1:8,P00552,0.719847,NO,198,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.719,-5.441,3.722,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.100394,0.00835002,0.719847 kka2_1:1_S104G,kka2_1:1_104,Kka2,kka2_1:1,P00552,0.719866,NO,104,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.436,-3.347,1.911,,0.536,T,A,0.27,-1.11,5.49,,63.64,HPP,-1.91433,0.520039,0.00555207,0.719866 beta-lactamase_0_D129K,beta-lactamase_0_129,TEM-1,beta-lactamase_0,P62593,0.71991,NO,129,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.816,-3.42,2.604,,,,B,0.75,-0.69,2.66,,34.97,PAP,-0.818,0.0500837,0.00109178,0.71991 beta-lactamase_0_T112C,beta-lactamase_0_112,TEM-1,beta-lactamase_0,P62593,0.71992,NO,112,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.186,-5.027,2.841,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.0500837,0.00531334,0.71992 kka2_1:2_F133V,kka2_1:2_133,Kka2,kka2_1:2,P00552,0.719924,NO,133,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-0.871,-3.355,2.484,,0.178,.,B,0.58,0.43,1.999,,42.42,OHA,-0.871667,0.295029,0.00182168,0.719924 kka2_1:4_W69L,kka2_1:4_69,Kka2,kka2_1:4,P00552,0.719977,NO,69,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-0.859,-3.385,2.526,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.168804,0.0012874,0.719977 beta-lactamase_0_A40P,beta-lactamase_0_40,TEM-1,beta-lactamase_0,P62593,0.71998,NO,40,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.402,-3.856,2.454,,0.155,S,B,0.46,0.21,0.783,,73.78,OHB,-1.40267,0.0500837,0.00490026,0.71998 beta-lactamase_0_W288I,beta-lactamase_0_288,TEM-1,beta-lactamase_0,P62593,0.72003,NO,288,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,,,,,,,,,,,,,BHO,,0.0500837,,0.72003 beta-lactamase_S233P,beta-lactamase_233,TEM-1,beta-lactamase,P62593,0.720033,NO,233,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.886,-2.778,0.892,4.98121,0.016,E,B,0.48,-1.01,5.361,,77.62,BPO,-1.17267,0.221079,0.00311415,0.720033 beta-lactamase_156_I244H,beta-lactamase_156_244,TEM-1,beta-lactamase_156,P62593,0.720069,NO,244,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.555,-4.957,3.402,,,E,B,0.48,-0.84,1.325,,77.62,OHH,-1.385,0.111618,0.00605379,0.720069 beta-lactamase_L49N,beta-lactamase_49,TEM-1,beta-lactamase,P62593,0.720078,NO,49,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.897,-3.842,1.945,5.86005,0.131,T,A,1.3,0.04,3.112,,64.69,AHP,-1.99233,0.221079,0.00401477,0.720078 WW_domain_D201Q,WW_domain_201,Yap65,WW_domain,P46937,0.720169,NO,201,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.369,-3.484,2.115,4.90312,,,,,,20.806,20.806,70.04,PAO,-1.456,0.153962,0.00248402,0.720169 kka2_1:8_A65P,kka2_1:8_65,Kka2,kka2_1:8,P00552,0.720202,NO,65,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.744,-4.019,2.275,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.100394,0.00709258,0.720202 kka2_1:8_A65P,kka2_1:8_65,Kka2,kka2_1:8,P00552,0.720202,NO,65,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.744,-4.019,2.275,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.100394,0.00709258,0.720202 beta-lactamase_0_L284H,beta-lactamase_0_284,TEM-1,beta-lactamase_0,P62593,0.720224,NO,284,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.981,,,,0.848,H,A,2.89,0.67,4.544,,77.62,PHH,-1.82133,0.0500837,0.0686156,0.720224 PSD95pdz3_G324E,PSD95pdz3_324,PSD95pdz3,PSD95pdz3,P31016,0.720311,NO,324,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.008,-3.347,2.339,4.98881,,,,,10.4525,,,,HOH,-1.293,0.0758425,0.00103462,0.720311 beta-lactamase_D48V,beta-lactamase_48,TEM-1,beta-lactamase,P62593,0.720383,NO,48,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.101,-3.719,2.618,4.89966,0.189,E,B,0.23,0.21,1.281,,50.35,HAH,-1.62467,0.221079,0.0027273,0.720383 beta-lactamase_2500_L192W,beta-lactamase_2500_192,TEM-1,beta-lactamase_2500,P62593,0.720427,NO,192,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.254,-5.176,3.922,,0.095,H,A,0.55,0.35,1.902,,60.14,HHP,-1.41833,0.361275,0.00558728,0.720427 kka2_1:1_M197V,kka2_1:1_197,Kka2,kka2_1:1,P00552,0.72043,NO,197,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.707,-2.226,0.519,,0.121,E,B,1.59,-1.19,2.097,,65.53,HHH,-1.847,0.520039,0.00921295,0.72043 beta-lactamase_E35C,beta-lactamase_35,TEM-1,beta-lactamase,P62593,0.720522,NO,35,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-0.869,-5.31,4.441,5.10723,0.15,H,A,0.52,0.21,1.081,,46.85,HAA,-1.88667,0.221079,0.00174441,0.720522 beta-lactamase_G76Y,beta-lactamase_76,TEM-1,beta-lactamase,P62593,0.720522,NO,76,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.189,-4.36,3.171,4.73862,,H,A,2.05,-0.67,3.059,,67.83,OOH,-1.22267,0.221079,0.00476637,0.720522 beta-lactamase_39_G234Q,beta-lactamase_39_234,TEM-1,beta-lactamase_39,P62593,0.720752,NO,234,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.62,-4.124,3.504,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.0495842,0.000889577,0.720752 beta-lactamase_2500_P217C,beta-lactamase_2500_217,TEM-1,beta-lactamase_2500,P62593,0.720785,NO,217,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-2.062,-5.064,3.002,,0.496,I,A,0.52,-0.33,0.431,,74.48,OOH,-1.64333,0.361275,0.00463211,0.720785 kka2_1:1_P132A,kka2_1:1_132,Kka2,kka2_1:1,P00552,0.720787,NO,132,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.775,-3.073,2.298,,0.692,.,A,0.52,0.56,0.224,,44.7,OOH,-0.825667,0.520039,0.0018489,0.720787 kka2_1:8_L126P,kka2_1:8_126,Kka2,kka2_1:8,P00552,0.72081,NO,126,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.246,-4.15,2.904,,0.285,S,B,1.59,0.12,4.443,,51.89,PHA,-1.744,0.100394,0.0066485,0.72081 kka2_1:8_L126P,kka2_1:8_126,Kka2,kka2_1:8,P00552,0.72081,NO,126,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.246,-4.15,2.904,,0.285,S,B,1.59,0.12,4.443,,51.89,PHA,-1.744,0.100394,0.0066485,0.72081 WW_domain_D201T,WW_domain_201,Yap65,WW_domain,P46937,0.720828,NO,201,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.369,-2.164,0.795,4.90312,,,,,,20.806,20.806,70.04,PAO,-1.456,0.153962,0.00248402,0.720828 beta-lactamase_0_N173Y,beta-lactamase_0_173,TEM-1,beta-lactamase_0,P62593,0.720902,NO,173,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-2.663,-4.409,1.746,,1.044,T,l,0.61,1.25,1.133,,77.62,OPA,-1.46633,0.0500837,0.0033769,0.720902 kka2_1:4_C77V,kka2_1:4_77,Kka2,kka2_1:4,P00552,0.720928,NO,77,C,V,CV,Special,Hydrophobic,5.07,5.60847,0.538465,192,121,117,-4,108.5,140,31.5,-1.477,-2.554,1.077,,0.229,B,b,0.46,-0.57,2.499,,63.26,OOH,-1.55667,0.168804,0.00441216,0.720928 kka2_1:2_P179M,kka2_1:2_179,Kka2,kka2_1:2,P00552,0.720931,NO,179,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.974,-4.581,3.607,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.295029,0.00298346,0.720931 kka2_1:1_W15L,kka2_1:1_15,Kka2,kka2_1:1,P00552,0.720982,NO,15,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-1.392,-1.643,0.251,,0.01,G,A,0.47,0.15,20.149,20.149,52.27,HHH,-2.10533,0.520039,0.00585505,0.720982 kka2_1:4_F203M,kka2_1:4_203,Kka2,kka2_1:4,P00552,0.721031,NO,203,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-0.911,-4.239,3.328,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.168804,0.00318738,0.721031 beta-lactamase_A40E,beta-lactamase_40,TEM-1,beta-lactamase,P62593,0.721055,NO,40,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.402,-3.641,2.239,4.9697,0.155,S,B,1.2,0.21,1.714,,73.78,OHB,-1.40267,0.221079,0.00490026,0.721055 beta-lactamase_2500_H110C,beta-lactamase_2500_110,TEM-1,beta-lactamase_2500,P62593,0.721106,NO,110,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-1.706,-5.217,3.511,,0.341,G,a,0.17,1.08,31.31,31.31,64.69,BBH,-1.73333,0.361275,0.00441499,0.721106 beta-lactamase_156_I244D,beta-lactamase_156_244,TEM-1,beta-lactamase_156,P62593,0.721107,NO,244,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.555,-3.943,2.388,,,E,B,0.48,-0.84,1.325,,77.62,OHH,-1.385,0.111618,0.00605379,0.721107 kka2_1:1_A224E,kka2_1:1_224,Kka2,kka2_1:1,P00552,0.721126,NO,224,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.977,-3.569,2.592,,,H,A,0.46,-1.26,1.725,,63.64,HHP,-1.41033,0.520039,0.00352047,0.721126 kka2_1:1_T146N,kka2_1:1_146,Kka2,kka2_1:1,P00552,0.721163,NO,146,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.978,-3.146,0.168,,0.281,H,A,0.82,0.78,2.105,,92.05,BPB,-1.96833,0.520039,0.00606474,0.721163 kka2_1:2_V186A,kka2_1:2_186,Kka2,kka2_1:2,P00552,0.721178,NO,186,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.011,-3.042,2.031,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.295029,0.00409703,0.721178 beta-lactamase_39_D155G,beta-lactamase_39_155,TEM-1,beta-lactamase_39,P62593,0.721233,NO,155,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.889,-3.177,2.288,,0.049,,B,0.75,-0.9,3.208,,64.69,OAB,-1.62267,0.0495842,0.00135315,0.721233 kka2_1:1_H8Y,kka2_1:1_8,Kka2,kka2_1:1,P00552,0.721294,NO,8,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-2.759,-3.943,1.184,,,,,,,16.971,16.971,71.59,HBH,-2.25467,0.520039,0.00256422,0.721294 kka2_1:4_Y218N,kka2_1:4_218,Kka2,kka2_1:4,P00552,0.721301,NO,218,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-1.438,-3.871,2.433,,0.122,H,A,0.21,-0.69,1.022,,56.06,BHP,-1.17533,0.168804,0.0126098,0.721301 kka2_1:8_G30R,kka2_1:8_30,Kka2,kka2_1:8,P00552,0.72131,NO,30,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.596,-3.961,3.365,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.100394,0.00159208,0.72131 kka2_1:8_G30R,kka2_1:8_30,Kka2,kka2_1:8,P00552,0.72131,NO,30,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.596,-3.961,3.365,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.100394,0.00159208,0.72131 kka2_1:1_D220A,kka2_1:1_220,Kka2,kka2_1:1,P00552,0.721347,NO,220,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.787,-3.298,2.511,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.520039,0.00158066,0.721347 kka2_1:4_R258L,kka2_1:4_258,Kka2,kka2_1:4,P00552,0.721375,NO,258,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.626,-2.791,1.165,,0.316,H,A,1.2,-0.85,2.655,,53.03,HBH,-1.25933,0.168804,0.00983174,0.721375 kka2_1:8_E63G,kka2_1:8_63,Kka2,kka2_1:8,P00552,0.721398,NO,63,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-0.762,-3.386,2.624,,0.043,H,A,1.52,-0.43,,,,AAH,-1.283,0.100394,0.00118399,0.721398 kka2_1:8_E63G,kka2_1:8_63,Kka2,kka2_1:8,P00552,0.721398,NO,63,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-0.762,-3.386,2.624,,0.043,H,A,1.52,-0.43,,,,AAH,-1.283,0.100394,0.00118399,0.721398 beta-lactamase_625_T187W,beta-lactamase_625_187,TEM-1,beta-lactamase_625,P62593,0.721444,NO,187,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.401,-5.371,3.97,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.213352,0.00491782,0.721444 beta-lactamase_2500_D161E,beta-lactamase_2500_161,TEM-1,beta-lactamase_2500,P62593,0.721448,NO,161,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.891,-2.299,1.408,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.361275,0.000897697,0.721448 PSD95pdz3_A376S,PSD95pdz3_376,PSD95pdz3,PSD95pdz3,P31016,0.721451,NO,376,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.307,-2.617,1.31,4.72134,,,,,17.108,,,,HHH,-1.49567,0.0758425,0.000341232,0.721451 kka2_1:4_R140V,kka2_1:4_140,Kka2,kka2_1:4,P00552,0.721471,NO,140,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.351,-3.736,2.385,,0.12,H,A,1.2,0.2,2.561,,53.03,BBH,-1.885,0.168804,0.00430167,0.721471 beta-lactamase_625_A246M,beta-lactamase_625_246,TEM-1,beta-lactamase_625,P62593,0.721501,NO,246,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.121,-2.882,0.761,,0.01,E,B,0.46,-1.01,1.201,,73.78,HHH,-1.55633,0.213352,0.00569458,0.721501 beta-lactamase_0_L146T,beta-lactamase_0_146,TEM-1,beta-lactamase_0,P62593,0.721566,NO,146,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.462,-3.533,2.071,,0.007,H,A,0.55,-0.56,2.051,,64.69,AHP,-1.656,0.0500837,0.00474542,0.721566 beta-lactamase_A132G,beta-lactamase_132,TEM-1,beta-lactamase,P62593,0.72168,NO,132,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.9,-3.009,2.109,4.58504,,H,A,2.34,-0.93,2.217,,64.69,PHH,-1.138,0.221079,0.000962524,0.72168 beta-lactamase_F228W,beta-lactamase_228,TEM-1,beta-lactamase,P62593,0.721707,NO,228,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-2.342,-5.275,2.933,5.33448,0.154,E,B,1.1,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.221079,0.0046669,0.721707 kka2_1:1_H124N,kka2_1:1_124,Kka2,kka2_1:1,P00552,0.721754,NO,124,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-0.84,-3.251,2.411,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.520039,0.00211296,0.721754 kka2_1:1_L107M,kka2_1:1_107,Kka2,kka2_1:1,P00552,0.72186,NO,107,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.238,-2.856,1.618,,0.197,.,B,0.55,-1.1,3.542,,71.59,BHH,-2.143,0.520039,0.00561937,0.72186 beta-lactamase_156_T131E,beta-lactamase_156_131,TEM-1,beta-lactamase_156,P62593,0.721945,NO,131,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.328,-3.523,2.195,,,H,A,0.22,-0.69,2.031,,67.48,PPH,-1.00867,0.111618,0.00345886,0.721945 beta-lactamase_625_M180P,beta-lactamase_625_180,TEM-1,beta-lactamase_625,P62593,0.721967,NO,180,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-2.795,-2.76,-0.035,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.213352,0.00552048,0.721967 beta-lactamase_156_L218W,beta-lactamase_156_218,TEM-1,beta-lactamase_156,P62593,0.722016,NO,218,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.391,-5.26,3.869,,,I,b,0.55,-0.53,17.202,17.202,74.48,OHH,-1.58867,0.111618,0.00618274,0.722016 beta-lactamase_156_Y262Q,beta-lactamase_156_262,TEM-1,beta-lactamase_156,P62593,0.722093,NO,262,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.111618,0.00853516,0.722093 beta-lactamase_R91V,beta-lactamase_91,TEM-1,beta-lactamase,P62593,0.722116,NO,91,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.392,-3.661,2.269,5.92536,0.444,,B,0.68,0.96,1.318,,50.35,OBB,-1.73367,0.221079,0.00380226,0.722116 kka2_1:1_E149K,kka2_1:1_149,Kka2,kka2_1:1,P00552,0.72213,NO,149,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.994,-2.785,0.791,,0.674,H,A,1.04,1.63,3.671,,71.59,HAH,-1.59667,0.520039,0.00803343,0.72213 Pab1_K156Q,Pab1_156,Pab1,Pab1,P04147,0.722244,NO,156,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.083,-3.266,2.183,,0.406,E,B,1.82,-0.26,,,,PBH,-1.58167,0.175299,0.000316767,0.722244 beta-lactamase_0_L284N,beta-lactamase_0_284,TEM-1,beta-lactamase_0,P62593,0.72226,NO,284,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.981,,,,0.848,H,A,2.89,0.67,4.544,,77.62,PHH,-1.82133,0.0500837,0.0686156,0.72226 gb1_K239P,gb1_239,gb1,gb1,P06654,0.722272,NO,239,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-3.043,-3.572,0.529,,,,,,,1.326,,45.54,HBO,-2.31467,0.177985,0.00207004,0.722272 kka2_1:4_V80H,kka2_1:4_80,Kka2,kka2_1:4,P00552,0.722292,NO,80,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.144,-4.98,3.836,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.168804,0.00488211,0.722292 beta-lactamase_0_L160N,beta-lactamase_0_160,TEM-1,beta-lactamase_0,P62593,0.722313,NO,160,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.977,-4.165,3.188,,0.022,,B,0.55,-0.6,0.68,,44.41,BHA,-0.936,0.0500837,0.00193775,0.722313 WW_domain_T182N,WW_domain_182,Yap65,WW_domain,P46937,0.722337,NO,182,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.149,-3.225,2.076,6.20597,,,,,,,,,BPP,-1.483,0.153962,0.00294574,0.722337 Pab1_F173W,Pab1_173,Pab1,Pab1,P04147,0.722363,NO,173,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.477,-4.204,2.727,,,E,B,0.87,-0.16,1.636,,63.26,BHA,-1.36967,0.175299,0.00148779,0.722363 beta-lactamase_D212H,beta-lactamase_212,TEM-1,beta-lactamase,P62593,0.722393,NO,212,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.624,-4.56,2.936,4.9705,0.037,,b,1.3,-0.58,12.482,,74.48,HAB,-1.77667,0.221079,0.00644302,0.722393 kka2_1:8_M148F,kka2_1:8_148,Kka2,kka2_1:8,P00552,0.72248,NO,148,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.847,-4.011,2.164,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.100394,0.00982664,0.72248 kka2_1:8_M148F,kka2_1:8_148,Kka2,kka2_1:8,P00552,0.72248,NO,148,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.847,-4.011,2.164,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.100394,0.00982664,0.72248 kka2_1:1_M148Q,kka2_1:1_148,Kka2,kka2_1:1,P00552,0.722561,NO,148,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.847,-4.147,2.3,,0.268,H,A,1.59,0.71,4.618,,64.39,BHA,-1.65467,0.520039,0.00982664,0.722561 kka2_1:8_N200V,kka2_1:8_200,Kka2,kka2_1:8,P00552,0.722574,NO,200,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-2.446,-3.862,1.416,,0.756,T,L,0.43,-0.08,2.528,,64.39,APO,-2.08,0.100394,0.00838549,0.722574 kka2_1:8_N200V,kka2_1:8_200,Kka2,kka2_1:8,P00552,0.722574,NO,200,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-2.446,-3.862,1.416,,0.756,T,L,0.43,-0.08,2.528,,64.39,APO,-2.08,0.100394,0.00838549,0.722574 Pab1_V198D,Pab1_198,Pab1,Pab1,P04147,0.722804,NO,198,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.113,-3.736,2.623,,0.008,E,B,0.61,0.91,,,,HHH,-1.32933,0.175299,0.000268557,0.722804 beta-lactamase_I229A,beta-lactamase_229,TEM-1,beta-lactamase,P62593,0.72284,NO,229,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.267,-3.077,1.81,5.0911,0.083,E,B,1,-0.76,1.114,,50,HHH,-1.58767,0.221079,0.00477249,0.72284 beta-lactamase_2500_E62V,beta-lactamase_2500_62,TEM-1,beta-lactamase_2500,P62593,0.722894,NO,62,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.193,-3.636,2.443,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.361275,0.00264802,0.722894 beta-lactamase_L247A,beta-lactamase_247,TEM-1,beta-lactamase,P62593,0.722919,NO,247,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.48,-2.56,1.08,5.28771,0.007,E,B,2.89,-0.72,2.951,,63.99,HHO,-1.79833,0.221079,0.00611275,0.722919 kka2_1:2_A137W,kka2_1:2_137,Kka2,kka2_1:2,P00552,0.722953,NO,137,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.156,-2.974,0.818,,0.029,H,A,0.46,0.34,1.323,,63.26,PHB,-2.559,0.295029,0.00515054,0.722953 beta-lactamase_L197C,beta-lactamase_197,TEM-1,beta-lactamase,P62593,0.722956,NO,197,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.853,-4.635,3.782,5.19172,0.007,S,B,1.3,0.33,1.756,,60.14,HHP,-1.833,0.221079,0.00144602,0.722956 beta-lactamase_0_K109H,beta-lactamase_0_109,TEM-1,beta-lactamase_0,P62593,0.722972,NO,109,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.734,-3.369,1.635,,0.787,G,A,2.34,2.21,15.473,15.473,72.73,ABB,-1.63333,0.0500837,0.00462493,0.722972 beta-lactamase_2500_M127D,beta-lactamase_2500_127,TEM-1,beta-lactamase_2500,P62593,0.722975,NO,127,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-2.251,-3.966,1.715,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.361275,0.00437927,0.722975 kka2_1:2_I196Q,kka2_1:2_196,Kka2,kka2_1:2,P00552,0.72302,NO,196,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-2.115,-4.384,2.269,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.295029,0.0107273,0.72302 kka2_1:1_H188D,kka2_1:1_188,Kka2,kka2_1:1,P00552,0.723047,NO,188,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-0.913,-3.495,2.582,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.520039,0.00273139,0.723047 kka2_1:1_L243M,kka2_1:1_243,Kka2,kka2_1:1,P00552,0.723063,NO,243,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-2.651,-4.688,2.037,,0.277,H,A,0.55,-0.67,4.334,,92.05,HHH,-2.03767,0.520039,0.00884927,0.723063 kka2_1:8_L39R,kka2_1:8_39,Kka2,kka2_1:8,P00552,0.723071,NO,39,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.223,-4.155,2.932,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.100394,0.00493618,0.723071 kka2_1:8_L39R,kka2_1:8_39,Kka2,kka2_1:8,P00552,0.723071,NO,39,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.223,-4.155,2.932,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.100394,0.00493618,0.723071 Pab1_K131G,Pab1_131,Pab1,Pab1,P04147,0.723097,NO,131,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.083,-3.175,2.092,,0.462,E,B,1.82,0.57,,,,HBP,-1.12467,0.175299,0.000349395,0.723097 beta-lactamase_625_Y103I,beta-lactamase_625_103,TEM-1,beta-lactamase_625,P62593,0.723105,NO,103,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-1.33,-3.874,2.544,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.213352,0.00443048,0.723105 beta-lactamase_R59S,beta-lactamase_59,TEM-1,beta-lactamase,P62593,0.72313,NO,59,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.345,-2.706,1.361,5.49837,0.329,S,L,0.68,-0.09,1.806,,73.08,HBO,-2.24267,0.221079,0.00318082,0.72313 gb1_A260V,gb1_260,gb1,gb1,P06654,0.723173,NO,260,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.486,-2.018,0.532,,,,,,,0.173,,9.6,HHP,-1.70967,0.177985,0.0055808,0.723173 gb1_L238G,gb1_238,gb1,gb1,P06654,0.723173,NO,238,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-2.98,-3.289,0.309,,,,,,,0.504,,45.54,PHB,-2.58633,0.177985,0.00205885,0.723173 Pab1_G126R,Pab1_126,Pab1,Pab1,P04147,0.723176,NO,126,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.985,-3.744,2.759,,0.011,T,A,0.46,-0.07,2.349,,80.42,OOP,-1.032,0.175299,0.00109814,0.723176 beta-lactamase_0_N274I,beta-lactamase_0_274,TEM-1,beta-lactamase_0,P62593,0.723198,NO,274,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.0500837,0.0110418,0.723198 kka2_1:8_H162F,kka2_1:8_162,Kka2,kka2_1:8,P00552,0.72323,NO,162,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-2.319,-4.187,1.868,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.100394,0.00616145,0.72323 kka2_1:8_H162F,kka2_1:8_162,Kka2,kka2_1:8,P00552,0.72323,NO,162,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-2.319,-4.187,1.868,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.100394,0.00616145,0.72323 beta-lactamase_0_L199C,beta-lactamase_0_199,TEM-1,beta-lactamase_0,P62593,0.723404,NO,199,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-2.942,-5.078,2.136,,0.832,H,A,0.55,0.42,10.85,10.85,77.62,PHH,-2.32933,0.0500837,0.0048649,0.723404 kka2_1:4_R122G,kka2_1:4_122,Kka2,kka2_1:4,P00552,0.723479,NO,122,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.175,-2.63,0.455,,0.487,H,A,0.16,0.26,16.436,16.436,71.59,BBH,-1.53833,0.168804,0.00736512,0.723479 beta-lactamase_T178A,beta-lactamase_178,TEM-1,beta-lactamase,P62593,0.723544,NO,178,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-0.791,-2.853,2.062,5.06452,0.029,E,B,0.3,-1.07,,,,APP,-0.947667,0.221079,0.000684366,0.723544 kka2_1:4_I29F,kka2_1:4_29,Kka2,kka2_1:4,P00552,0.723587,NO,29,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.692,-4.042,2.35,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.168804,0.00619521,0.723587 beta-lactamase_0_L38V,beta-lactamase_0_38,TEM-1,beta-lactamase_0,P62593,0.723607,NO,38,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.343,-2.209,0.866,,0.088,H,A,0.55,0.2,13.556,13.556,64.34,PHO,-1.78033,0.0500837,0.00373244,0.723607 kka2_1:1_A229E,kka2_1:1_229,Kka2,kka2_1:1,P00552,0.723645,NO,229,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.739,-2.079,0.34,,0.32,H,A,0.46,-0.7,6.549,,63.64,HHA,-1.851,0.520039,0.00942138,0.723645 kka2_1:1_G95R,kka2_1:1_95,Kka2,kka2_1:1,P00552,0.723694,NO,95,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-2.403,-3.111,0.708,,0.126,E,B,0.29,-0.74,7.822,,71.59,HOA,-2.198,0.520039,0.00743616,0.723694 kka2_1:4_G30C,kka2_1:4_30,Kka2,kka2_1:4,P00552,0.723713,NO,30,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.596,-5.115,4.519,,0.54,S,g,0.29,3.76,,,,HOO,-1.51133,0.168804,0.00159208,0.723713 kka2_1:4_I196Q,kka2_1:4_196,Kka2,kka2_1:4,P00552,0.723741,NO,196,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-2.115,-4.384,2.269,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.168804,0.0107273,0.723741 kka2_1:8_K50S,kka2_1:8_50,Kka2,kka2_1:8,P00552,0.723796,NO,50,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-0.833,-3.233,2.4,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.100394,0.00138626,0.723796 kka2_1:8_K50S,kka2_1:8_50,Kka2,kka2_1:8,P00552,0.723796,NO,50,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-0.833,-3.233,2.4,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.100394,0.00138626,0.723796 beta-lactamase_0_V82D,beta-lactamase_0_82,TEM-1,beta-lactamase_0,P62593,0.723805,NO,82,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.325,-3.879,2.554,,0.267,H,A,0.44,0.08,1.893,,93.01,BHA,-1.28567,0.0500837,0.00397046,0.723805 kka2_1:4_A191E,kka2_1:4_191,Kka2,kka2_1:4,P00552,0.723896,NO,191,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.831,-3.502,2.671,,,.,b,0.46,-0.94,2.046,,50,AHO,-0.868667,0.168804,0.00338807,0.723896 beta-lactamase_T116Y,beta-lactamase_116,TEM-1,beta-lactamase,P62593,0.723967,NO,116,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.28,-4.295,3.015,4.78335,0.115,E,B,0.69,-0.12,0.343,,67.48,HPH,-1.39967,0.221079,0.00336175,0.723967 beta-lactamase_2500_S241C,beta-lactamase_2500_241,TEM-1,beta-lactamase_2500,P62593,0.724042,NO,241,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.361275,0.00452736,0.724042 gb1_L238S,gb1_238,gb1,gb1,P06654,0.72407,NO,238,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-2.98,-3.17,0.19,,,,,,,0.504,,45.54,PHB,-2.58633,0.177985,0.00205885,0.72407 kka2_1:1_I246S,kka2_1:1_246,Kka2,kka2_1:1,P00552,0.724082,NO,246,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-2.008,-3.645,1.637,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.520039,0.0139479,0.724082 PSD95pdz3_G324Q,PSD95pdz3_324,PSD95pdz3,PSD95pdz3,P31016,0.724125,NO,324,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.008,-3.806,2.798,4.98881,,,,,10.4525,,,,HOH,-1.293,0.0758425,0.00103462,0.724125 beta-lactamase_625_V259F,beta-lactamase_625_259,TEM-1,beta-lactamase_625,P62593,0.724178,NO,259,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.213352,0.0070773,0.724178 kka2_1:1_L126P,kka2_1:1_126,Kka2,kka2_1:1,P00552,0.724196,NO,126,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.246,-4.15,2.904,,0.285,S,B,0.55,0.12,0.302,,51.89,PHA,-1.744,0.520039,0.0066485,0.724196 beta-lactamase_39_L248H,beta-lactamase_39_248,TEM-1,beta-lactamase_39,P62593,0.724207,NO,248,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.0495842,0.00428493,0.724207 kka2_1:8_G201V,kka2_1:8_201,Kka2,kka2_1:8,P00552,0.724215,NO,201,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.56,-3.892,2.332,,0.149,T,l,0.75,-0.57,2.152,,52.65,POB,-1.92233,0.100394,0.00820117,0.724215 kka2_1:8_G201V,kka2_1:8_201,Kka2,kka2_1:8,P00552,0.724215,NO,201,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.56,-3.892,2.332,,0.149,T,l,0.75,-0.57,2.152,,52.65,POB,-1.92233,0.100394,0.00820117,0.724215 beta-lactamase_0_F70T,beta-lactamase_0_70,TEM-1,beta-lactamase_0,P62593,0.724235,NO,70,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.169,-3.571,2.402,,,H,A,0.58,-1.34,2.153,,63.99,PHB,-0.980667,0.0500837,0.00193499,0.724235 kka2_1:1_P179R,kka2_1:1_179,Kka2,kka2_1:1,P00552,0.724283,NO,179,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.974,-4.006,3.032,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.520039,0.00298346,0.724283 kka2_1:8_L212I,kka2_1:8_212,Kka2,kka2_1:8,P00552,0.724405,NO,212,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.904,-3.012,2.108,,,,B,1.59,-0.78,1.708,,42.42,BHO,-0.799667,0.100394,0.0031426,0.724405 kka2_1:8_L212I,kka2_1:8_212,Kka2,kka2_1:8,P00552,0.724405,NO,212,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.904,-3.012,2.108,,,,B,1.59,-0.78,1.708,,42.42,BHO,-0.799667,0.100394,0.0031426,0.724405 kka2_1:8_Q136P,kka2_1:8_136,Kka2,kka2_1:8,P00552,0.724481,NO,136,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-3.021,-2.734,-0.287,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.100394,0.00624149,0.724481 kka2_1:8_Q136P,kka2_1:8_136,Kka2,kka2_1:8,P00552,0.724481,NO,136,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-3.021,-2.734,-0.287,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.100394,0.00624149,0.724481 kka2_1:8_V198N,kka2_1:8_198,Kka2,kka2_1:8,P00552,0.724481,NO,198,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.719,-3.977,2.258,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.100394,0.00835002,0.724481 kka2_1:8_V198N,kka2_1:8_198,Kka2,kka2_1:8,P00552,0.724481,NO,198,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.719,-3.977,2.258,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.100394,0.00835002,0.724481 Pab1_F170M,Pab1_170,Pab1,Pab1,P04147,0.724523,NO,170,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.269,-4.176,2.907,,0.331,E,B,0.87,-1.31,2.061,,79.72,OHH,-1.06367,0.175299,0.000540225,0.724523 beta-lactamase_I11N,beta-lactamase_11,TEM-1,beta-lactamase,P62593,0.724532,NO,11,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.745,-3.984,2.239,,,,,,,3.135,,66.08,HHO,-1.79467,0.221079,0.00261325,0.724532 kka2_1:8_I228Q,kka2_1:8_228,Kka2,kka2_1:8,P00552,0.724557,NO,228,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.142,-4.362,3.22,,,H,A,1.52,-1.2,1.521,,71.59,AHH,-1.54633,0.100394,0.00458834,0.724557 kka2_1:8_I228Q,kka2_1:8_228,Kka2,kka2_1:8,P00552,0.724557,NO,228,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.142,-4.362,3.22,,,H,A,1.52,-1.2,1.521,,71.59,AHH,-1.54633,0.100394,0.00458834,0.724557 beta-lactamase_M115R,beta-lactamase_115,TEM-1,beta-lactamase,P62593,0.72458,NO,115,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.389,-2.862,1.473,4.89743,0.019,E,B,1.3,0.08,1.236,,69.58,OHP,-1.25433,0.221079,0.0034337,0.72458 beta-lactamase_0_L55E,beta-lactamase_0_55,TEM-1,beta-lactamase_0,P62593,0.724613,NO,55,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.86,-3.84,1.98,,0.372,E,A,0.55,-0.36,1.967,,63.99,HHA,-2.247,0.0500837,0.00403741,0.724613 kka2_1:1_A144S,kka2_1:1_144,Kka2,kka2_1:1,P00552,0.724624,NO,144,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.859,-3.103,2.244,,,H,A,0.46,0.21,0.842,,52.65,BHB,-1.72933,0.520039,0.00231095,0.724624 beta-lactamase_0_N134E,beta-lactamase_0_134,TEM-1,beta-lactamase_0,P62593,0.72466,NO,134,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-0.879,-3.212,2.333,,0.138,H,A,0.61,-0.6,3.776,,53.15,HPH,-1.02233,0.0500837,0.000644786,0.72466 kka2_1:2_T72P,kka2_1:2_72,Kka2,kka2_1:2,P00552,0.724801,NO,72,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.38,-4.008,1.628,,0.784,H,A,0.82,0.29,6.463,,65.53,HPP,-2.238,0.295029,0.00750756,0.724801 beta-lactamase_2500_F228H,beta-lactamase_2500_228,TEM-1,beta-lactamase_2500,P62593,0.724841,NO,228,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-2.342,-3.331,0.989,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.361275,0.0046669,0.724841 kka2_1:2_D250V,kka2_1:2_250,Kka2,kka2_1:2,P00552,0.724895,NO,250,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.015,-3.813,2.798,,0.274,.,b,0.75,-0.46,3.796,,51.89,OAP,-1.83933,0.295029,0.0177103,0.724895 kka2_1:2_I221V,kka2_1:2_221,Kka2,kka2_1:2,P00552,0.724935,NO,221,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.739,-2.261,0.522,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.295029,0.00945908,0.724935 gb1_L233Q,gb1_233,gb1,gb1,P06654,0.724961,NO,233,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-2.678,-2.035,-0.643,,,,,,,0.822,,45.54,HHP,-2.30267,0.177985,0.00266958,0.724961 gb1_L238A,gb1_238,gb1,gb1,P06654,0.724961,NO,238,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-2.98,-3.008,0.028,,,,,,,0.504,,45.54,PHB,-2.58633,0.177985,0.00205885,0.724961 gb1_T237P,gb1_237,gb1,gb1,P06654,0.724961,NO,237,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.736,-3.617,1.881,,,,,,,0.218,,11.83,BPH,-2.27833,0.177985,0.00275316,0.724961 gb1_Y229Q,gb1_229,gb1,gb1,P06654,0.724961,NO,229,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-1.282,-3.635,2.353,,,,,,,,,,PHB,-1.4915,0.177985,0.00366605,0.724961 beta-lactamase_L73N,beta-lactamase_73,TEM-1,beta-lactamase,P62593,0.724965,NO,73,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.507,-4.234,2.727,5.84139,,H,A,1.75,-0.64,2.09,,67.83,HHH,-1.487,0.221079,0.00488983,0.724965 beta-lactamase_N272Q,beta-lactamase_272,TEM-1,beta-lactamase,P62593,0.724965,NO,272,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-1.127,-3.677,2.55,5.37826,0.081,H,A,0.09,-0.97,1.468,,63.64,BPB,-1.56333,0.221079,0.00545371,0.724965 beta-lactamase_T262F,beta-lactamase_262,TEM-1,beta-lactamase,P62593,0.724965,NO,262,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.332,-4.211,2.879,5.06002,0.108,E,B,0.3,-0.55,1.423,,67.83,PPO,-2.081,0.221079,0.00853516,0.724965 E1_Ubiquitin_R72T,E1_Ubiquitin_72,Uba1,E1_Ubiquitin,P0CG63,0.725022,NO,72,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.184,-3.239,2.055,,0.077,,B,0.16,-0.1,,,,HBH,-1.08733,0.18783,0.00129853,0.725022 beta-lactamase_156_L218E,beta-lactamase_156_218,TEM-1,beta-lactamase_156,P62593,0.725059,NO,218,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.391,-3.611,2.22,,,I,b,0.55,-0.53,17.202,17.202,74.48,OHH,-1.58867,0.111618,0.00618274,0.725059 beta-lactamase_625_D174A,beta-lactamase_625_174,TEM-1,beta-lactamase_625,P62593,0.725214,NO,174,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.738,-3.303,2.565,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.213352,0.00125633,0.725214 beta-lactamase_156_D207P,beta-lactamase_156_207,TEM-1,beta-lactamase_156,P62593,0.725275,NO,207,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.064,-3.955,1.891,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.111618,0.00592942,0.725275 beta-lactamase_0_R176F,beta-lactamase_0_176,TEM-1,beta-lactamase_0,P62593,0.725278,NO,176,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-0.863,-4.292,3.429,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.0500837,0.00105554,0.725278 Pab1_K140E,Pab1_140,Pab1,Pab1,P04147,0.725387,NO,140,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.083,-2.807,1.724,,0.345,H,A,,-0.73,,,,PBH,-1.20767,0.175299,0.000337366,0.725387 beta-lactamase_I93H,beta-lactamase_93,TEM-1,beta-lactamase,P62593,0.72539,NO,93,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.401,-5.004,3.603,5.74695,0.128,E,B,0.77,0.44,1.757,,67.83,BHB,-1.873,0.221079,0.00527066,0.72539 kka2_1:8_T146P,kka2_1:8_146,Kka2,kka2_1:8,P00552,0.72543,NO,146,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.978,-4.011,1.033,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.100394,0.00606474,0.72543 kka2_1:8_T146P,kka2_1:8_146,Kka2,kka2_1:8,P00552,0.72543,NO,146,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.978,-4.011,1.033,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.100394,0.00606474,0.72543 beta-lactamase_0_G253W,beta-lactamase_0_253,TEM-1,beta-lactamase_0,P62593,0.725436,NO,253,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.0500837,0.00786358,0.725436 kka2_1:4_L94R,kka2_1:4_94,Kka2,kka2_1:4,P00552,0.725482,NO,94,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.618,-3.994,2.376,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.168804,0.00520888,0.725482 beta-lactamase_625_L219P,beta-lactamase_625_219,TEM-1,beta-lactamase_625,P62593,0.725496,NO,219,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.313,-4.214,2.901,,,I,A,0.55,-0.51,5.627,,74.48,HHB,-1.21533,0.213352,0.00664345,0.725496 beta-lactamase_156_W288P,beta-lactamase_156_288,TEM-1,beta-lactamase_156,P62593,0.72556,NO,288,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,,,,,,,,,,,,,BHO,,0.111618,,0.72556 kka2_1:4_L193D,kka2_1:4_193,Kka2,kka2_1:4,P00552,0.725567,NO,193,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.983,-4.051,3.068,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.168804,0.00480179,0.725567 kka2_1:1_Q219T,kka2_1:1_219,Kka2,kka2_1:1,P00552,0.725569,NO,219,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-0.93,-3.473,2.543,,0.088,H,A,0.4,-0.85,1.917,,50,HPA,-1.05167,0.520039,0.00237913,0.725569 beta-lactamase_0_S68Q,beta-lactamase_0_68,TEM-1,beta-lactamase_0,P62593,0.725578,NO,68,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-0.913,-3.7,2.787,,0.064,G,A,0.27,-1.03,1.441,,64.69,HPP,-1.37233,0.0500837,0.000800065,0.725578 kka2_1:8_R211S,kka2_1:8_211,Kka2,kka2_1:8,P00552,0.725582,NO,211,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-0.899,-3.475,2.576,,0.12,T,a,0.16,-0.39,0.615,,49.62,OBH,-0.966,0.100394,0.00204888,0.725582 kka2_1:8_R211S,kka2_1:8_211,Kka2,kka2_1:8,P00552,0.725582,NO,211,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-0.899,-3.475,2.576,,0.12,T,a,0.16,-0.39,0.615,,49.62,OBH,-0.966,0.100394,0.00204888,0.725582 kka2_1:1_A13C,kka2_1:1_13,Kka2,kka2_1:1,P00552,0.725596,NO,13,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.248,-3.798,1.55,,0.689,G,A,0.46,0.99,25.015,25.015,92.05,OHH,-1.646,0.520039,0.00784241,0.725596 kka2_1:8_L260V,kka2_1:8_260,Kka2,kka2_1:8,P00552,0.725657,NO,260,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.741,-2.882,2.141,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.100394,0.0233782,0.725657 kka2_1:8_L260V,kka2_1:8_260,Kka2,kka2_1:8,P00552,0.725657,NO,260,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.741,-2.882,2.141,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.100394,0.0233782,0.725657 beta-lactamase_2500_K213E,beta-lactamase_2500_213,TEM-1,beta-lactamase_2500,P62593,0.72566,NO,213,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.81,-2.688,0.878,,0.67,,A,2.34,0.29,1.668,,67.83,ABH,-1.57767,0.361275,0.00610411,0.72566 beta-lactamase_625_P143N,beta-lactamase_625_143,TEM-1,beta-lactamase_625,P62593,0.725663,NO,143,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.967,-3.954,2.987,,0.075,H,A,0.52,-0.37,1.445,,66.78,OOB,-1.354,0.213352,0.00114551,0.725663 beta-lactamase_T178V,beta-lactamase_178,TEM-1,beta-lactamase,P62593,0.725708,NO,178,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-0.791,-3.079,2.288,5.06452,0.029,E,B,0.3,-1.07,,,,APP,-0.947667,0.221079,0.000684366,0.725708 kka2_1:2_P12S,kka2_1:2_12,Kka2,kka2_1:2,P00552,0.725735,NO,12,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.853,-3.336,2.483,,,.,B,0.52,1.25,0.261,,48.11,POH,-1.80767,0.295029,0.00500011,0.725735 beta-lactamase_V257Y,beta-lactamase_257,TEM-1,beta-lactamase,P62593,0.725793,NO,257,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.533,-4.132,2.599,5.31999,,E,B,0.96,-0.7,1.463,,58.74,HHH,-1.70967,0.221079,0.00756629,0.725793 Ubiquitin_A46M,Ubiquitin_46,Uba1,Ubiquitin,P0CG48,0.725806,NO,46,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.77,-4.684,2.914,5.38761,0.398,T,L,2.34,-0.8,6.506,,51.09,HHO,-1.505,0.205827,0.000581142,0.725806 Ubiquitin_I3R,Ubiquitin_3,Uba1,Ubiquitin,P0CG48,0.725806,NO,3,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.402,-4.099,2.697,4.80819,,E,B,,-0.78,,,,PHH,-1.54533,0.205827,0.000836911,0.725806 Ubiquitin_K11I,Ubiquitin_11,Uba1,Ubiquitin,P0CG48,0.725806,NO,11,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.354,-2.813,1.459,5.16813,0.401,,B,2.81,0.84,0.335,,25.84,OBP,-1.346,0.205827,0.000535553,0.725806 Ubiquitin_K6I,Ubiquitin_6,Uba1,Ubiquitin,P0CG48,0.725806,NO,6,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.093,-4.023,2.93,4.84211,0.35,E,B,1.82,-0.62,1.502,,71.82,HBP,-1.36133,0.205827,0.000784795,0.725806 Ubiquitin_Q2S,Ubiquitin_2,Uba1,Ubiquitin,P0CG48,0.725806,NO,2,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-1.7,-3.327,1.627,4.89203,0.475,E,B,,0.1,,,,OPH,-1.551,0.205827,0.00085006,0.725806 Ubiquitin_T12N,Ubiquitin_12,Uba1,Ubiquitin,P0CG48,0.725806,NO,12,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.288,-3.477,2.189,4.93973,0.417,E,B,0.8,0.12,2.762,,25.84,BPH,-1.39867,0.205827,0.000657544,0.725806 beta-lactamase_0_M115E,beta-lactamase_0_115,TEM-1,beta-lactamase_0,P62593,0.725808,NO,115,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.389,-3.76,2.371,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.0500837,0.0034337,0.725808 gb1_L238H,gb1_238,gb1,gb1,P06654,0.725848,NO,238,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-2.98,-4.226,1.246,,,,,,,0.504,,45.54,PHB,-2.58633,0.177985,0.00205885,0.725848 gb1_Y259S,gb1_259,gb1,gb1,P06654,0.725848,NO,259,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-1.78,-3.528,1.748,,,,,,,0.131,,11.83,PHH,-1.787,0.177985,0.00464313,0.725848 kka2_1:2_P194D,kka2_1:2_194,Kka2,kka2_1:2,P00552,0.725849,NO,194,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.846,-2.601,1.755,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.295029,0.00314194,0.725849 PSD95pdz3_D348T,PSD95pdz3_348,PSD95pdz3,PSD95pdz3,P31016,0.725857,NO,348,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.264,-3.103,1.839,5.02473,,,,,16.8925,,,,HAH,-1.306,0.0758425,0.000731866,0.725857 kka2_1:1_E199N,kka2_1:1_199,Kka2,kka2_1:1,P00552,0.725897,NO,199,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.234,-3.807,1.573,,0.508,E,B,1.04,-0.43,3.012,,65.53,HAP,-2.133,0.520039,0.00854122,0.725897 kka2_1:4_T28N,kka2_1:4_28,Kka2,kka2_1:4,P00552,0.725907,NO,28,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.883,-3.817,1.934,,0.353,S,B,0.82,2.02,4.415,,63.64,PPH,-1.74467,0.168804,0.00743084,0.725907 kka2_1:4_L260C,kka2_1:4_260,Kka2,kka2_1:4,P00552,0.725927,NO,260,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.741,-4.665,3.924,,0.022,H,A,0.55,-0.52,,,,HHA,-0.845667,0.168804,0.0233782,0.725927 beta-lactamase_0_Y262R,beta-lactamase_0_262,TEM-1,beta-lactamase_0,P62593,0.725951,NO,262,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.0500837,0.00853516,0.725951 kka2_1:4_L60A,kka2_1:4_60,Kka2,kka2_1:4,P00552,0.725985,NO,60,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.997,-3.185,2.188,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.168804,0.00262176,0.725985 beta-lactamase_0_P165K,beta-lactamase_0_165,TEM-1,beta-lactamase_0,P62593,0.725988,NO,165,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.373,-3.528,2.155,,0.203,T,A,0.52,-0.31,3.242,,73.78,AOA,-1.359,0.0500837,0.00549538,0.725988 kka2_1:8_D82Y,kka2_1:8_82,Kka2,kka2_1:8,P00552,0.725998,NO,82,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.946,-4.406,2.46,,0.341,E,b,0.29,0.52,7.463,,63.64,HAH,-1.98,0.100394,0.00637516,0.725998 kka2_1:8_D82Y,kka2_1:8_82,Kka2,kka2_1:8,P00552,0.725998,NO,82,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.946,-4.406,2.46,,0.341,E,b,0.29,0.52,7.463,,63.64,HAH,-1.98,0.100394,0.00637516,0.725998 kka2_1:2_W24G,kka2_1:2_24,Kka2,kka2_1:2,P00552,0.726033,NO,24,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-1.779,-3.736,1.957,,0.477,E,B,1.51,-0.21,2.666,,56.06,AHH,-2.24467,0.295029,0.00631564,0.726033 kka2_1:2_L241D,kka2_1:2_241,Kka2,kka2_1:2,P00552,0.726062,NO,241,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.158,-4.14,2.982,,0.08,H,A,0.55,-0.82,1.598,,63.26,HHH,-1.58533,0.295029,0.0117299,0.726062 kka2_1:1_P249T,kka2_1:1_249,Kka2,kka2_1:1,P00552,0.726129,NO,249,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.867,-2.639,0.772,,0.406,.,B,0.52,-0.01,8.037,8.037,92.05,HOA,-1.66867,0.520039,0.011045,0.726129 WW_domain_Q195M,WW_domain_195,Yap65,WW_domain,P46937,0.726183,NO,195,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-1.839,-2.781,0.942,5.22735,,,,,,1.803,,70.04,APP,-1.719,0.153962,0.00394344,0.726183 kka2_1:1_A110S,kka2_1:1_110,Kka2,kka2_1:1,P00552,0.726209,NO,110,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.064,-2.748,0.684,,0.175,H,A,1.04,-1.19,11.755,,71.59,OHA,-1.91867,0.520039,0.00759851,0.726209 beta-lactamase_0_L38K,beta-lactamase_0_38,TEM-1,beta-lactamase_0,P62593,0.726304,NO,38,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.343,-3.749,2.406,,0.088,H,A,0.55,0.2,13.556,13.556,64.34,PHO,-1.78033,0.0500837,0.00373244,0.726304 kka2_1:2_V113T,kka2_1:2_113,Kka2,kka2_1:2,P00552,0.726371,NO,113,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.233,-3.45,2.217,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.295029,0.00650191,0.726371 beta-lactamase_2500_T264F,beta-lactamase_2500_264,TEM-1,beta-lactamase_2500,P62593,0.726394,NO,264,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.361275,0.0119399,0.726394 kka2_1:4_P179K,kka2_1:4_179,Kka2,kka2_1:4,P00552,0.726403,NO,179,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.974,-3.58,2.606,,0.113,,B,0.52,0.69,10.913,10.913,56.06,HOA,-2.19867,0.168804,0.00298346,0.726403 beta-lactamase_0_I125P,beta-lactamase_0_125,TEM-1,beta-lactamase_0,P62593,0.726406,NO,125,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.441,-4.116,2.675,,,H,A,0.48,-0.7,1.874,,63.29,HHP,-1.248,0.0500837,0.00383964,0.726406 beta-lactamase_0_L146W,beta-lactamase_0_146,TEM-1,beta-lactamase_0,P62593,0.726434,NO,146,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.462,-2.894,1.432,,0.007,H,A,0.55,-0.56,2.051,,64.69,AHP,-1.656,0.0500837,0.00474542,0.726434 kka2_1:1_E17H,kka2_1:1_17,Kka2,kka2_1:1,P00552,0.726599,NO,17,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.154,-3.247,1.093,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.520039,0.00688738,0.726599 kka2_1:8_P194Q,kka2_1:8_194,Kka2,kka2_1:8,P00552,0.726603,NO,194,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.846,-3.927,3.081,,0.308,G,A,0.52,-1.19,4.861,,53.03,HOP,-0.888333,0.100394,0.00314194,0.726603 kka2_1:8_P194Q,kka2_1:8_194,Kka2,kka2_1:8,P00552,0.726603,NO,194,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.846,-3.927,3.081,,0.308,G,A,0.52,-1.19,4.861,,53.03,HOP,-0.888333,0.100394,0.00314194,0.726603 kka2_1:2_G245R,kka2_1:2_245,Kka2,kka2_1:2,P00552,0.726652,NO,245,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.812,-3.916,3.104,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.295029,0.00683899,0.726652 beta-lactamase_2500_E195I,beta-lactamase_2500_195,TEM-1,beta-lactamase_2500,P62593,0.726733,NO,195,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.186,-4.191,2.005,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.361275,0.00496565,0.726733 beta-lactamase_0_D207P,beta-lactamase_0_207,TEM-1,beta-lactamase_0,P62593,0.726764,NO,207,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.064,-3.955,1.891,,0.409,H,A,0.75,0.12,5.277,,77.62,HAH,-1.77033,0.0500837,0.00592942,0.726764 kka2_1:2_I254F,kka2_1:2_254,Kka2,kka2_1:2,P00552,0.726807,NO,254,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.933,-3.851,1.918,,0.135,H,A,1.52,-0.6,2.562,,71.59,BHH,-1.668,0.295029,0.0132375,0.726807 beta-lactamase_A9D,beta-lactamase_9,TEM-1,beta-lactamase,P62593,0.726869,NO,9,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.147,-3.795,1.648,,,,,,,5.128,,72.73,HHH,-2.04267,0.221079,0.00247263,0.726869 beta-lactamase_0_E35C,beta-lactamase_0_35,TEM-1,beta-lactamase_0,P62593,0.726905,NO,35,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-0.869,-5.31,4.441,,0.15,H,A,1.04,0.21,0.664,,46.85,HAA,-1.88667,0.0500837,0.00174441,0.726905 kka2_1:8_Q163P,kka2_1:8_163,Kka2,kka2_1:8,P00552,0.726981,NO,163,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.162,-4.062,1.9,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.100394,0.00719507,0.726981 kka2_1:8_Q163P,kka2_1:8_163,Kka2,kka2_1:8,P00552,0.726981,NO,163,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.162,-4.062,1.9,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.100394,0.00719507,0.726981 beta-lactamase_2500_A34F,beta-lactamase_2500_34,TEM-1,beta-lactamase_2500,P62593,0.727089,NO,34,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.059,-3.937,1.878,,,H,A,0.46,-0.54,2.921,,73.78,AHA,-1.74967,0.361275,0.00407913,0.727089 PSD95pdz3_V362E,PSD95pdz3_362,PSD95pdz3,PSD95pdz3,P31016,0.727122,NO,362,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.465,-3.347,1.882,4.99436,,,,,19.6443,,,,PHP,-1.46467,0.0758425,0.000538527,0.727122 kka2_1:1_E142G,kka2_1:1_142,Kka2,kka2_1:1,P00552,0.727141,NO,142,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.221,-2.713,0.492,,0.471,H,A,1.52,0.85,3.626,,65.53,HAB,-2.08033,0.520039,0.00748883,0.727141 kka2_1:2_L152H,kka2_1:2_152,Kka2,kka2_1:2,P00552,0.727145,NO,152,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.521,-4.868,3.347,,0.547,.,A,0.55,1.36,4.526,,63.64,OHH,-1.162,0.295029,0.00674868,0.727145 beta-lactamase_39_L284D,beta-lactamase_39_284,TEM-1,beta-lactamase_39,P62593,0.727148,NO,284,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.0495842,0.0686156,0.727148 kka2_1:4_R145T,kka2_1:4_145,Kka2,kka2_1:4,P00552,0.727168,NO,145,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.804,-3.648,1.844,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.168804,0.00846663,0.727168 beta-lactamase_625_E56I,beta-lactamase_625_56,TEM-1,beta-lactamase_625,P62593,0.727169,NO,56,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.043,-3.825,1.782,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.213352,0.00238534,0.727169 beta-lactamase_0_K254L,beta-lactamase_0_254,TEM-1,beta-lactamase_0,P62593,0.72718,NO,254,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.0500837,0.00369,0.72718 beta-lactamase_0_A34K,beta-lactamase_0_34,TEM-1,beta-lactamase_0,P62593,0.727202,NO,34,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.059,-3.736,1.677,,,H,A,0.46,-0.54,3.998,,73.78,AHA,-1.74967,0.0500837,0.00407913,0.727202 beta-lactamase_V72L,beta-lactamase_72,TEM-1,beta-lactamase,P62593,0.72722,NO,72,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.658,-2.403,0.745,5.80324,,H,A,2.78,-1.03,2.964,,65.73,BHH,-1.32167,0.221079,0.00501194,0.72722 beta-lactamase_2500_G216W,beta-lactamase_2500_216,TEM-1,beta-lactamase_2500,P62593,0.727258,NO,216,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.477,-5.45,3.973,,0.437,I,A,0.29,-0.58,1.983,,74.48,HOO,-1.68067,0.361275,0.00639568,0.727258 kka2_1:1_Y244H,kka2_1:1_244,Kka2,kka2_1:1,P00552,0.727263,NO,244,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-0.775,-3.808,3.033,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.520039,0.00453187,0.727263 kka2_1:8_D62Y,kka2_1:8_62,Kka2,kka2_1:8,P00552,0.727358,NO,62,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.591,-4.391,2.8,,0.262,H,A,0.29,0.08,5.58,,64.39,PAA,-1.77833,0.100394,0.00744243,0.727358 kka2_1:8_D62Y,kka2_1:8_62,Kka2,kka2_1:8,P00552,0.727358,NO,62,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.591,-4.391,2.8,,0.262,H,A,0.29,0.08,5.58,,64.39,PAA,-1.77833,0.100394,0.00744243,0.727358 PSD95pdz3_Q358D,PSD95pdz3_358,PSD95pdz3,PSD95pdz3,P31016,0.727446,NO,358,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-1.699,-2.925,1.226,5.21282,,,,,14.8844,,,,APH,-1.531,0.0758425,0.000594893,0.727446 beta-lactamase_G154Y,beta-lactamase_154,TEM-1,beta-lactamase,P62593,0.727537,NO,154,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.823,-4.424,3.601,5.40944,0.54,T,l,0.77,-0.56,2.283,,64.69,HOA,-1.635,0.221079,0.00180205,0.727537 kka2_1:4_A229D,kka2_1:4_229,Kka2,kka2_1:4,P00552,0.727565,NO,229,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.739,-3.667,1.928,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.168804,0.00942138,0.727565 gb1_F278M,gb1_278,gb1,gb1,P06654,0.727606,NO,278,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.418,-4.204,2.786,,,,,,,3.233,,35.71,PHP,-1.503,0.177985,0.00295699,0.727606 beta-lactamase_L197Y,beta-lactamase_197,TEM-1,beta-lactamase,P62593,0.727757,NO,197,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.853,-3.986,3.133,5.19172,0.007,S,B,1.3,0.33,1.756,,60.14,HHP,-1.833,0.221079,0.00144602,0.727757 beta-lactamase_0_Y44N,beta-lactamase_0_44,TEM-1,beta-lactamase_0,P62593,0.727787,NO,44,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-2.547,-4.162,1.615,,,E,B,0.21,-0.45,1.751,,73.78,OHH,-1.86267,0.0500837,0.00426364,0.727787 beta-lactamase_156_D174R,beta-lactamase_156_174,TEM-1,beta-lactamase_156,P62593,0.7279,NO,174,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.738,-3.933,3.195,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.111618,0.00125633,0.7279 kka2_1:8_E182L,kka2_1:8_182,Kka2,kka2_1:8,P00552,0.727923,NO,182,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.516,-3.646,2.13,,0.326,,B,1.52,0.75,2.568,,65.53,OAA,-1.806,0.100394,0.00641548,0.727923 kka2_1:8_E182L,kka2_1:8_182,Kka2,kka2_1:8,P00552,0.727923,NO,182,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.516,-3.646,2.13,,0.326,,B,1.52,0.75,2.568,,65.53,OAA,-1.806,0.100394,0.00641548,0.727923 kka2_1:2_E235T,kka2_1:2_235,Kka2,kka2_1:2,P00552,0.727931,NO,235,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.955,-3.009,1.054,,0.631,H,A,1.04,0.12,26.048,26.048,65.53,OAH,-2.07267,0.295029,0.0102806,0.727931 beta-lactamase_2500_A124C,beta-lactamase_2500_124,TEM-1,beta-lactamase_2500,P62593,0.727967,NO,124,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.181,-4.594,3.413,,,H,A,0.46,-0.9,0.314,,64.34,HHH,-1.152,0.361275,0.00481399,0.727967 kka2_1:1_R226S,kka2_1:1_226,Kka2,kka2_1:1,P00552,0.728015,NO,226,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.392,-2.638,1.246,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.520039,0.0108032,0.728015 beta-lactamase_L10K,beta-lactamase_10,TEM-1,beta-lactamase,P62593,0.728057,NO,10,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.623,-3.704,2.081,,,,,,,2.467,,65.38,HHH,-1.83833,0.221079,0.00296968,0.728057 beta-lactamase_2500_K286C,beta-lactamase_2500_286,TEM-1,beta-lactamase_2500,P62593,0.728115,NO,286,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.361275,,0.728115 beta-lactamase_625_N168M,beta-lactamase_625_168,TEM-1,beta-lactamase_625,P62593,0.728126,NO,168,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-1.029,-4.683,3.654,,0.113,G,A,0.61,-0.4,1.014,,44.41,HPA,-1.13233,0.213352,0.00288667,0.728126 beta-lactamase_0_G194R,beta-lactamase_0_194,TEM-1,beta-lactamase_0,P62593,0.728149,NO,194,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.396,-3.912,2.516,,0.276,S,b,0.29,0.36,3.017,,67.83,POA,-1.832,0.0500837,0.00392163,0.728149 kka2_1:8_G30V,kka2_1:8_30,Kka2,kka2_1:8,P00552,0.728149,NO,30,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.596,-3.782,3.186,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.100394,0.00159208,0.728149 kka2_1:8_G30V,kka2_1:8_30,Kka2,kka2_1:8,P00552,0.728149,NO,30,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.596,-3.782,3.186,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.100394,0.00159208,0.728149 kka2_1:8_K50Q,kka2_1:8_50,Kka2,kka2_1:8,P00552,0.728149,NO,50,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-0.833,-3.501,2.668,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.100394,0.00138626,0.728149 kka2_1:8_K50Q,kka2_1:8_50,Kka2,kka2_1:8,P00552,0.728149,NO,50,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-0.833,-3.501,2.668,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.100394,0.00138626,0.728149 kka2_1:2_G151V,kka2_1:2_151,Kka2,kka2_1:2,P00552,0.728152,NO,151,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.873,-3.846,2.973,,0.678,T,l,0.29,1.36,1.357,,49.62,HOH,-1.11433,0.295029,0.00339918,0.728152 beta-lactamase_0_S256A,beta-lactamase_0_256,TEM-1,beta-lactamase_0,P62593,0.728187,NO,256,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.0500837,0.00710634,0.728187 beta-lactamase_E87N,beta-lactamase_87,TEM-1,beta-lactamase,P62593,0.728222,NO,87,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.421,-3.684,2.263,5.41929,0.048,,B,0.52,0.92,1.754,,64.69,PAP,-1.969,0.221079,0.00337888,0.728222 kka2_1:1_I115D,kka2_1:1_115,Kka2,kka2_1:1,P00552,0.728297,NO,115,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.606,-4.12,2.514,,0.105,H,A,0.48,-1.18,0.878,,65.53,PHH,-2.205,0.520039,0.00836567,0.728297 beta-lactamase_A235N,beta-lactamase_235,TEM-1,beta-lactamase,P62593,0.728312,NO,235,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.266,-3.746,2.48,4.83024,0.32,E,B,0.52,-0.86,1.344,,50,OHO,-0.89,0.221079,0.00493474,0.728312 beta-lactamase_2500_G216R,beta-lactamase_2500_216,TEM-1,beta-lactamase_2500,P62593,0.728331,NO,216,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.477,-2.93,1.453,,0.437,I,A,0.29,-0.58,1.983,,74.48,HOO,-1.68067,0.361275,0.00639568,0.728331 PSD95pdz3_A376W,PSD95pdz3_376,PSD95pdz3,PSD95pdz3,P31016,0.728362,NO,376,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.307,-5.004,3.697,4.72134,,,,,17.108,,,,HHH,-1.49567,0.0758425,0.000341232,0.728362 beta-lactamase_0_S283D,beta-lactamase_0_283,TEM-1,beta-lactamase_0,P62593,0.72838,NO,283,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.0500837,0.0429138,0.72838 beta-lactamase_625_L120V,beta-lactamase_625_120,TEM-1,beta-lactamase_625,P62593,0.728428,NO,120,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.044,-3.031,1.987,,,H,A,0.55,-1.13,7.813,,64.69,AHO,-1.13633,0.213352,0.00143563,0.728428 kka2_1:1_G88V,kka2_1:1_88,Kka2,kka2_1:1,P00552,0.728434,NO,88,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.689,-2.928,1.239,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.520039,0.00685559,0.728434 kka2_1:8_D52K,kka2_1:8_52,Kka2,kka2_1:8,P00552,0.728449,NO,52,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.271,-3.096,0.825,,0.22,E,B,0.75,0.8,5.447,,71.59,PAH,-2.38367,0.100394,0.00175694,0.728449 kka2_1:8_D52K,kka2_1:8_52,Kka2,kka2_1:8,P00552,0.728449,NO,52,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.271,-3.096,0.825,,0.22,E,B,0.75,0.8,5.447,,71.59,PAH,-2.38367,0.100394,0.00175694,0.728449 kka2_1:2_G201C,kka2_1:2_201,Kka2,kka2_1:2,P00552,0.728451,NO,201,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.56,-3.58,2.02,,0.149,T,l,0.29,-0.57,16.092,16.092,52.65,POB,-1.92233,0.295029,0.00820117,0.728451 beta-lactamase_0_D161P,beta-lactamase_0_161,TEM-1,beta-lactamase_0,P62593,0.72846,NO,161,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.891,-3.704,2.813,,0.341,,A,0.75,-0.52,0.795,,61.19,HAB,-0.961333,0.0500837,0.000897697,0.72846 beta-lactamase_G76V,beta-lactamase_76,TEM-1,beta-lactamase,P62593,0.728478,NO,76,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.189,-3.485,2.296,4.73862,,H,A,2.05,-0.67,3.059,,67.83,OOH,-1.22267,0.221079,0.00476637,0.728478 beta-lactamase_N168I,beta-lactamase_168,TEM-1,beta-lactamase,P62593,0.728489,NO,168,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-1.029,-3.943,2.914,5.42128,0.113,G,A,0.09,-0.4,1.211,,44.41,HPA,-1.13233,0.221079,0.00288667,0.728489 kka2_1:2_P132T,kka2_1:2_132,Kka2,kka2_1:2,P00552,0.72852,NO,132,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.775,-3.417,2.642,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.295029,0.0018489,0.72852 beta-lactamase_0_G90M,beta-lactamase_0_90,TEM-1,beta-lactamase_0,P62593,0.728596,NO,90,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-2.091,-4.839,2.748,,0.598,T,A,0.29,0.32,2.04,,77.62,HOB,-1.52633,0.0500837,0.00490273,0.728596 beta-lactamase_0_E26W,beta-lactamase_0_26,TEM-1,beta-lactamase_0,P62593,0.728711,NO,26,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.454,-5.402,2.948,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.0500837,0.00297948,0.728711 kka2_1:2_P98S,kka2_1:2_98,Kka2,kka2_1:2,P00552,0.72873,NO,98,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.526,-2.565,1.039,,0.391,S,B,0.52,-0.65,2.82,,63.26,HOO,-1.19167,0.295029,0.00622754,0.72873 kka2_1:8_P179D,kka2_1:8_179,Kka2,kka2_1:8,P00552,0.728787,NO,179,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.974,-3.655,2.681,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.100394,0.00298346,0.728787 kka2_1:8_P179D,kka2_1:8_179,Kka2,kka2_1:8,P00552,0.728787,NO,179,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.974,-3.655,2.681,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.100394,0.00298346,0.728787 Pab1_S165D,Pab1_165,Pab1,Pab1,P04147,0.728829,NO,165,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.146,-3.061,1.915,,0.12,,a,,0.11,,,,BPB,-1.56867,0.175299,0.000307838,0.728829 beta-lactamase_39_A278P,beta-lactamase_39_278,TEM-1,beta-lactamase_39,P62593,0.728883,NO,278,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.0495842,0.0310297,0.728883 kka2_1:4_A108V,kka2_1:4_108,Kka2,kka2_1:4,P00552,0.728936,NO,108,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.061,-3.068,1.007,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.168804,0.00751209,0.728936 beta-lactamase_625_K213P,beta-lactamase_625_213,TEM-1,beta-lactamase_625,P62593,0.72894,NO,213,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.81,-3.901,2.091,,0.67,,A,2.34,0.29,3.924,,67.83,ABH,-1.57767,0.213352,0.00610411,0.72894 kka2_1:1_Y244L,kka2_1:1_244,Kka2,kka2_1:1,P00552,0.729086,NO,244,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-0.775,-3.161,2.386,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.520039,0.00453187,0.729086 beta-lactamase_Y103C,beta-lactamase_103,TEM-1,beta-lactamase,P62593,0.729106,NO,103,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-1.33,-5.047,3.717,5.71734,0.613,S,l,2.55,1.21,5.721,,63.29,AHP,-1.48767,0.221079,0.00443048,0.729106 beta-lactamase_156_A247D,beta-lactamase_156_247,TEM-1,beta-lactamase_156,P62593,0.729191,NO,247,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.111618,0.00611275,0.729191 PSD95pdz3_G356I,PSD95pdz3_356,PSD95pdz3,PSD95pdz3,P31016,0.729228,NO,356,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.008,-3.917,2.909,4.8656,,,,,11.9575,,,,BOA,-1.22933,0.0758425,0.000623061,0.729228 kka2_1:2_E169C,kka2_1:2_169,Kka2,kka2_1:2,P00552,0.729234,NO,169,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.996,-5.197,3.201,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.295029,0.00730086,0.729234 kka2_1:8_F37R,kka2_1:8_37,Kka2,kka2_1:8,P00552,0.729275,NO,37,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.427,-4.151,2.724,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.100394,0.00586193,0.729275 kka2_1:8_F37R,kka2_1:8_37,Kka2,kka2_1:8,P00552,0.729275,NO,37,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.427,-4.151,2.724,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.100394,0.00586193,0.729275 beta-lactamase_0_P172C,beta-lactamase_0_172,TEM-1,beta-lactamase_0,P62593,0.729334,NO,172,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.998,-4.977,3.979,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.0500837,0.00312594,0.729334 beta-lactamase_D231N,beta-lactamase_231,TEM-1,beta-lactamase,P62593,0.729407,NO,231,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.816,-3.272,2.456,5.06651,,E,B,1.22,-1.06,0.319,,65.38,HAB,-0.994,0.221079,0.00107395,0.729407 beta-lactamase_G279F,beta-lactamase_279,TEM-1,beta-lactamase,P62593,0.729407,NO,279,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.038,-4.266,3.228,4.53882,,H,A,0.46,-0.97,3.066,,62.59,HOH,-1.36467,0.221079,0.0192826,0.729407 beta-lactamase_0_P65E,beta-lactamase_0_65,TEM-1,beta-lactamase_0,P62593,0.729439,NO,65,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.894,-3.524,2.63,,0.098,E,B,0.52,-0.62,0.663,,40.56,HOH,-1.03233,0.0500837,0.00152776,0.729439 kka2_1:2_L123M,kka2_1:2_123,Kka2,kka2_1:2,P00552,0.729444,NO,123,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.888,-2.619,1.731,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.295029,0.00325188,0.729444 beta-lactamase_0_P25T,beta-lactamase_0_25,TEM-1,beta-lactamase_0,P62593,0.729447,NO,25,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.526,-3.483,1.957,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.0500837,0.00347571,0.729447 kka2_1:1_L193M,kka2_1:1_193,Kka2,kka2_1:1,P00552,0.729461,NO,193,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.983,-2.486,1.503,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.520039,0.00480179,0.729461 beta-lactamase_L28P,beta-lactamase_28,TEM-1,beta-lactamase,P62593,0.729499,NO,28,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.579,-4.027,2.448,5.42969,0.277,H,A,0.07,-0.16,19.748,19.748,93.01,PHH,-2.11333,0.221079,0.00359321,0.729499 beta-lactamase_D174T,beta-lactamase_174,TEM-1,beta-lactamase,P62593,0.729529,NO,174,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.738,-3.421,2.683,5.44133,0.238,,B,1.22,-0.1,,,,PAA,-1.91233,0.221079,0.00125633,0.729529 beta-lactamase_2500_S241N,beta-lactamase_2500_241,TEM-1,beta-lactamase_2500,P62593,0.729539,NO,241,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.361275,0.00452736,0.729539 beta-lactamase_0_V42K,beta-lactamase_0_42,TEM-1,beta-lactamase_0,P62593,0.72954,NO,42,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.564,-3.817,2.253,,0.017,E,B,0.44,-0.51,1.659,,63.99,BHO,-1.042,0.0500837,0.00404515,0.72954 kka2_1:1_A79D,kka2_1:1_79,Kka2,kka2_1:1,P00552,0.729589,NO,79,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.368,-2.473,0.105,,0.563,.,B,0.46,-0.43,7.792,7.792,71.59,HHH,-1.752,0.520039,0.00664821,0.729589 PSD95pdz3_I314W,PSD95pdz3_314,PSD95pdz3,PSD95pdz3,P31016,0.729615,NO,314,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.628,-5.099,3.471,5.39919,,,,,15.7775,0.397,,81.35,BHH,-1.61167,0.0758425,0.0012606,0.729615 beta-lactamase_2500_A278W,beta-lactamase_2500_278,TEM-1,beta-lactamase_2500,P62593,0.729641,NO,278,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.361275,0.0310297,0.729641 kka2_1:2_V84S,kka2_1:2_84,Kka2,kka2_1:2,P00552,0.729667,NO,84,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-2.279,-2.917,0.638,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.295029,0.00724019,0.729667 kka2_1:1_D33A,kka2_1:1_33,Kka2,kka2_1:1,P00552,0.729743,NO,33,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.186,-2.11,-0.076,,0.561,S,A,0.75,3.35,2.568,,71.59,PAH,-1.306,0.520039,0.00633568,0.729743 WW_domain_P174A,WW_domain_174,Yap65,WW_domain,P46937,0.729743,NO,174,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.035,-2.855,1.82,,,,,,,,,,HOH,-1.261,0.153962,0.000711366,0.729743 beta-lactamase_0_V42T,beta-lactamase_0_42,TEM-1,beta-lactamase_0,P62593,0.729784,NO,42,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.564,-3.48,1.916,,0.017,E,B,0.44,-0.51,1.659,,63.99,BHO,-1.042,0.0500837,0.00404515,0.729784 beta-lactamase_Q86P,beta-lactamase_86,TEM-1,beta-lactamase,P62593,0.729823,NO,86,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.4,-3.985,1.585,5.39897,0.696,S,A,0.12,2.38,2.105,,77.62,OPA,-1.61067,0.221079,0.00450027,0.729823 beta-lactamase_2500_Y95L,beta-lactamase_2500_95,TEM-1,beta-lactamase_2500,P62593,0.729851,NO,95,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-1.715,-2.545,0.83,,0.122,,b,0.21,-0.37,2.914,,77.62,BHP,-2.16167,0.361275,0.00479449,0.729851 beta-lactamase_0_E35T,beta-lactamase_0_35,TEM-1,beta-lactamase_0,P62593,0.729871,NO,35,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-0.869,-3.447,2.578,,0.15,H,A,1.04,0.21,0.664,,46.85,HAA,-1.88667,0.0500837,0.00174441,0.729871 kka2_1:2_V46E,kka2_1:2_46,Kka2,kka2_1:2,P00552,0.729873,NO,46,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-2.62,-3.655,1.035,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.295029,0.00631301,0.729873 kka2_1:2_M116A,kka2_1:2_116,Kka2,kka2_1:2,P00552,0.729877,NO,116,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-2.482,-2.16,-0.322,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.295029,0.00745147,0.729877 Pab1_V171M,Pab1_171,Pab1,Pab1,P04147,0.72995,NO,171,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.113,-3.847,2.734,,0.008,E,b,0.23,-0.34,,,,HHB,-1.19733,0.175299,0.000298662,0.72995 kka2_1:8_E182R,kka2_1:8_182,Kka2,kka2_1:8,P00552,0.730061,NO,182,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.516,-3.801,2.285,,0.326,,B,1.52,0.75,2.568,,65.53,OAA,-1.806,0.100394,0.00641548,0.730061 kka2_1:8_E182R,kka2_1:8_182,Kka2,kka2_1:8,P00552,0.730061,NO,182,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.516,-3.801,2.285,,0.326,,B,1.52,0.75,2.568,,65.53,OAA,-1.806,0.100394,0.00641548,0.730061 kka2_1:1_A224S,kka2_1:1_224,Kka2,kka2_1:1,P00552,0.730071,NO,224,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.977,-3.088,2.111,,,H,A,0.46,-1.26,1.725,,63.64,HHP,-1.41033,0.520039,0.00352047,0.730071 beta-lactamase_39_L136N,beta-lactamase_39_136,TEM-1,beta-lactamase_39,P62593,0.730118,NO,136,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.232,-4.217,2.985,,,H,A,0.55,-0.34,0.336,,48.95,HHH,-1.088,0.0495842,0.00442304,0.730118 kka2_1:2_G55V,kka2_1:2_55,Kka2,kka2_1:2,P00552,0.730123,NO,55,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.625,-3.678,2.053,,0.517,S,b,0.75,1.19,15.753,15.753,63.64,POH,-2.05967,0.295029,0.00667877,0.730123 kka2_1:1_G43R,kka2_1:1_43,Kka2,kka2_1:1,P00552,0.730126,NO,43,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.587,-2.733,1.146,,0.862,T,l,0.75,-0.67,2.247,,63.26,POB,-2.18533,0.520039,0.0071925,0.730126 beta-lactamase_0_P65F,beta-lactamase_0_65,TEM-1,beta-lactamase_0,P62593,0.730179,NO,65,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.894,-4.306,3.412,,0.098,E,B,0.52,-0.62,0.663,,40.56,HOH,-1.03233,0.0500837,0.00152776,0.730179 beta-lactamase_0_M115P,beta-lactamase_0_115,TEM-1,beta-lactamase_0,P62593,0.730183,NO,115,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.389,-4.034,2.645,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.0500837,0.0034337,0.730183 kka2_1:1_S204R,kka2_1:1_204,Kka2,kka2_1:1,P00552,0.730187,NO,204,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.353,-3.873,2.52,,0.144,E,A,0.27,-1.2,3.022,,65.53,HPO,-0.953333,0.520039,0.00881794,0.730187 kka2_1:2_P98E,kka2_1:2_98,Kka2,kka2_1:2,P00552,0.730207,NO,98,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.526,-2.413,0.887,,0.391,S,B,0.52,-0.65,2.82,,63.26,HOO,-1.19167,0.295029,0.00622754,0.730207 gb1_L231H,gb1_231,gb1,gb1,P06654,0.730209,NO,231,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.603,-4.003,2.4,,,,,,,0.219,,11.83,BHH,-1.82633,0.177985,0.00322797,0.730209 gb1_Y259N,gb1_259,gb1,gb1,P06654,0.730209,NO,259,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-1.78,-3.945,2.165,,,,,,,0.131,,11.83,PHH,-1.787,0.177985,0.00464313,0.730209 kka2_1:4_F264W,kka2_1:4_264,Kka2,kka2_1:4,P00552,0.730224,NO,264,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.02,-4.514,3.494,,0.296,,?,1.62,0.02,1.93,,71.59,HHO,-0.9655,0.168804,,0.730224 beta-lactamase_P143E,beta-lactamase_143,TEM-1,beta-lactamase,P62593,0.730227,NO,143,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.967,-3.58,2.613,5.16366,0.075,H,A,0.99,-0.37,0.479,,66.78,OOB,-1.354,0.221079,0.00114551,0.730227 beta-lactamase_39_G249M,beta-lactamase_39_249,TEM-1,beta-lactamase_39,P62593,0.730384,NO,249,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.312,,,,0.256,S,B,0.23,0.04,30.841,30.841,72.73,HOO,-1.81367,0.0495842,0.00220169,0.730384 beta-lactamase_G141Y,beta-lactamase_141,TEM-1,beta-lactamase,P62593,0.730394,NO,141,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.828,-4.424,3.596,5.03155,0.575,T,l,0.76,-0.28,0.198,,64.69,HOO,-1.08933,0.221079,0.0012419,0.730394 beta-lactamase_0_L137W,beta-lactamase_0_137,TEM-1,beta-lactamase_0,P62593,0.730423,NO,137,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.03,-5.164,4.134,,,H,A,0.55,-0.38,0.328,,42.31,HHP,-1.58933,0.0500837,0.00278599,0.730423 kka2_1:2_E169V,kka2_1:2_169,Kka2,kka2_1:2,P00552,0.730452,NO,169,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.996,-3.701,1.705,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.295029,0.00730086,0.730452 kka2_1:1_D156A,kka2_1:1_156,Kka2,kka2_1:1,P00552,0.730453,NO,156,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.696,-2.256,0.56,,0.884,T,A,0.75,1.87,1.044,,65.53,PAA,-1.765,0.520039,0.00926998,0.730453 beta-lactamase_C75L,beta-lactamase_75,TEM-1,beta-lactamase,P62593,0.730549,NO,75,C,L,CL,Special,Hydrophobic,5.07,9.7088,4.6388,198,121,131,10,108.5,166.7,58.2,-1.245,-3.28,2.035,4.88171,,H,A,0.25,-0.87,0.876,,50,HOO,-1.24333,0.221079,0.0034616,0.730549 beta-lactamase_0_E175D,beta-lactamase_0_175,TEM-1,beta-lactamase_0,P62593,0.730561,NO,175,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.336,-2.916,0.58,,0.551,,A,1.04,1.05,2.334,,77.62,AAB,-1.31233,0.0500837,0.00482205,0.730561 kka2_1:1_V36A,kka2_1:1_36,Kka2,kka2_1:1,P00552,0.730563,NO,36,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-0.898,-2.963,2.065,,0.292,E,B,0.44,0.21,0.278,,52.27,HHH,-1.484,0.520039,0.00245633,0.730563 kka2_1:1_V16L,kka2_1:1_16,Kka2,kka2_1:1,P00552,0.730706,NO,16,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-3.087,-2.643,-0.444,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.520039,0.00694011,0.730706 beta-lactamase_2500_T147D,beta-lactamase_2500_147,TEM-1,beta-lactamase_2500,P62593,0.730765,NO,147,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.149,-3.491,2.342,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.361275,0.00226017,0.730765 beta-lactamase_0_E145K,beta-lactamase_0_145,TEM-1,beta-lactamase_0,P62593,0.730766,NO,145,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.357,-3.472,1.115,,0.545,H,A,1.04,0.79,1.199,,77.62,BAH,-2.069,0.0500837,0.00553285,0.730766 beta-lactamase_0_K144D,beta-lactamase_0_144,TEM-1,beta-lactamase_0,P62593,0.73096,NO,144,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-2.388,-3.584,1.196,,0.863,H,A,2.34,1.27,5.696,,77.62,OBA,-1.904,0.0500837,0.00481141,0.73096 beta-lactamase_2500_E119H,beta-lactamase_2500_119,TEM-1,beta-lactamase_2500,P62593,0.730975,NO,119,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.412,-4.521,3.109,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.361275,0.00386966,0.730975 beta-lactamase_625_P250F,beta-lactamase_625_250,TEM-1,beta-lactamase_625,P62593,0.731067,NO,250,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.213352,0.00550899,0.731067 beta-lactamase_156_L284H,beta-lactamase_156_284,TEM-1,beta-lactamase_156,P62593,0.731077,NO,284,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.111618,0.0686156,0.731077 kka2_1:4_R121S,kka2_1:4_121,Kka2,kka2_1:4,P00552,0.73108,NO,121,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.552,-2.658,1.106,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.168804,0.00523326,0.73108 beta-lactamase_2500_T269F,beta-lactamase_2500_269,TEM-1,beta-lactamase_2500,P62593,0.731084,NO,269,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.361275,0.00950944,0.731084 PSD95pdz3_V386R,PSD95pdz3_386,PSD95pdz3,PSD95pdz3,P31016,0.731098,NO,386,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.465,-3.84,2.375,5.18836,,,,,17.5429,,,,PHP,-1.463,0.0758425,0.000184509,0.731098 kka2_1:2_R258S,kka2_1:2_258,Kka2,kka2_1:2,P00552,0.731105,NO,258,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.626,-3.501,1.875,,0.316,H,A,1.2,-0.85,7.485,7.485,53.03,HBH,-1.25933,0.295029,0.00983174,0.731105 beta-lactamase_0_K53P,beta-lactamase_0_53,TEM-1,beta-lactamase_0,P62593,0.731126,NO,53,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-2.313,-3.069,0.756,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.0500837,0.00383383,0.731126 PSD95pdz3_I359F,PSD95pdz3_359,PSD95pdz3,PSD95pdz3,P31016,0.731135,NO,359,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.63,-3.299,1.669,5.35151,,,,,14.8012,,,,PHH,-1.58667,0.0758425,0.000580694,0.731135 beta-lactamase_0_S241E,beta-lactamase_0_241,TEM-1,beta-lactamase_0,P62593,0.731142,NO,241,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.0500837,0.00452736,0.731142 beta-lactamase_2500_V214A,beta-lactamase_2500_214,TEM-1,beta-lactamase_2500,P62593,0.731176,NO,214,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.299,-2.434,1.135,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.361275,0.00628442,0.731176 kka2_1:1_D23Y,kka2_1:1_23,Kka2,kka2_1:1,P00552,0.731209,NO,23,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.459,-4.392,1.933,,0.695,E,B,0.75,-0.65,2.655,,65.53,HAH,-1.94033,0.520039,0.007195,0.731209 beta-lactamase_0_G85P,beta-lactamase_0_85,TEM-1,beta-lactamase_0,P62593,0.731212,NO,85,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.011,-3.891,2.88,,0.805,T,l,0.29,1.7,2.25,,63.64,HOP,-1.68733,0.0500837,0.00252173,0.731212 Pab1_N139F,Pab1_139,Pab1,Pab1,P04147,0.731248,NO,139,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-1.079,-4.109,3.03,,0.062,H,A,,-0.73,,,,APB,-1.09667,0.175299,0.000339145,0.731248 kka2_1:4_G95L,kka2_1:4_95,Kka2,kka2_1:4,P00552,0.731255,NO,95,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-2.403,-3.574,1.171,,0.126,E,B,0.29,-0.74,0.359,,71.59,HOA,-2.198,0.168804,0.00743616,0.731255 kka2_1:8_L223P,kka2_1:8_223,Kka2,kka2_1:8,P00552,0.731292,NO,223,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.861,-4.178,3.317,,,H,A,1.59,-1.24,1.017,,50,HHH,-0.854333,0.100394,0.00253574,0.731292 kka2_1:8_L223P,kka2_1:8_223,Kka2,kka2_1:8,P00552,0.731292,NO,223,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.861,-4.178,3.317,,,H,A,1.59,-1.24,1.017,,50,HHH,-0.854333,0.100394,0.00253574,0.731292 beta-lactamase_0_V29E,beta-lactamase_0_29,TEM-1,beta-lactamase_0,P62593,0.73132,NO,29,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-2.856,-1.855,-1.001,,0.733,H,A,0.44,-0.78,21.916,21.916,93.01,HHB,-2.24733,0.0500837,0.00318969,0.73132 beta-lactamase_0_I206N,beta-lactamase_0_206,TEM-1,beta-lactamase_0,P62593,0.731352,NO,206,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-2.429,-3.933,1.504,,0.173,H,A,0.48,-0.34,3.411,,77.62,HHA,-1.805,0.0500837,0.00528934,0.731352 beta-lactamase_F17P,beta-lactamase_17,TEM-1,beta-lactamase,P62593,0.73148,NO,17,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-2.337,-2.813,0.476,,,,,,,2.192,,67.83,HHO,-2.17733,0.221079,0.00216499,0.73148 kka2_1:8_R89G,kka2_1:8_89,Kka2,kka2_1:8,P00552,0.731553,NO,89,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.548,-2.87,1.322,,0.209,E,B,1.2,1.41,25.3,25.3,64.39,OBA,-1.89867,0.100394,0.00524373,0.731553 kka2_1:8_R89G,kka2_1:8_89,Kka2,kka2_1:8,P00552,0.731553,NO,89,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.548,-2.87,1.322,,0.209,E,B,1.2,1.41,25.3,25.3,64.39,OBA,-1.89867,0.100394,0.00524373,0.731553 kka2_1:2_E199F,kka2_1:2_199,Kka2,kka2_1:2,P00552,0.731566,NO,199,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.234,-4.372,2.138,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.295029,0.00854122,0.731566 kka2_1:8_V49G,kka2_1:8_49,Kka2,kka2_1:8,P00552,0.731664,NO,49,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.614,-3.739,2.125,,,E,B,1.48,-0.77,1.31,,64.39,HHB,-1.3,0.100394,0.00615685,0.731664 kka2_1:8_V49G,kka2_1:8_49,Kka2,kka2_1:8,P00552,0.731664,NO,49,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.614,-3.739,2.125,,,E,B,1.48,-0.77,1.31,,64.39,HHB,-1.3,0.100394,0.00615685,0.731664 beta-lactamase_I11H,beta-lactamase_11,TEM-1,beta-lactamase,P62593,0.731672,NO,11,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.745,-4.743,2.998,,,,,,,3.135,,66.08,HHO,-1.79467,0.221079,0.00261325,0.731672 kka2_1:1_D238T,kka2_1:1_238,Kka2,kka2_1:1,P00552,0.731683,NO,238,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.83,-2.681,-0.149,,0.604,H,A,0.75,-0.33,11.329,11.329,92.05,HAB,-2.633,0.520039,0.0113863,0.731683 beta-lactamase_2500_L136V,beta-lactamase_2500_136,TEM-1,beta-lactamase_2500,P62593,0.731721,NO,136,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.232,-1.932,0.7,,,H,A,0.55,-0.34,1.36,,48.95,HHH,-1.088,0.361275,0.00442304,0.731721 Pab1_K166W,Pab1_166,Pab1,Pab1,P04147,0.731809,NO,166,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.262,-5.215,3.953,,0.299,,l,,0,,,,PBO,-1.21033,0.175299,0.0011038,0.731809 kka2_1:4_M120T,kka2_1:4_120,Kka2,kka2_1:4,P00552,0.731818,NO,120,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-3.877,-3.448,-0.429,,,H,A,0.55,-0.42,2.259,,92.05,HHB,-2.16733,0.168804,0.00265808,0.731818 kka2_1:2_G74K,kka2_1:2_74,Kka2,kka2_1:2,P00552,0.731833,NO,74,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.18,-3.609,2.429,,0.621,T,l,0.75,0.2,1.446,,64.39,POH,-1.91667,0.295029,0.00587035,0.731833 kka2_1:2_A117Q,kka2_1:2_117,Kka2,kka2_1:2,P00552,0.731883,NO,117,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.828,-3.991,3.163,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.295029,0.00282984,0.731883 kka2_1:8_L158E,kka2_1:8_158,Kka2,kka2_1:8,P00552,0.73195,NO,158,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.947,-3.926,1.979,,0.095,.,B,0.55,0.77,1.607,,63.64,AHA,-1.25333,0.100394,0.00529068,0.73195 kka2_1:8_L158E,kka2_1:8_158,Kka2,kka2_1:8,P00552,0.73195,NO,158,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.947,-3.926,1.979,,0.095,.,B,0.55,0.77,1.607,,63.64,AHA,-1.25333,0.100394,0.00529068,0.73195 kka2_1:2_R89H,kka2_1:2_89,Kka2,kka2_1:2,P00552,0.732009,NO,89,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.548,-2.435,0.887,,0.209,E,B,1.2,1.41,14.396,14.396,64.39,OBA,-1.89867,0.295029,0.00524373,0.732009 kka2_1:2_A222S,kka2_1:2_222,Kka2,kka2_1:2,P00552,0.732027,NO,222,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.725,-2.964,2.239,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.295029,0.00207657,0.732027 kka2_1:8_W236H,kka2_1:8_236,Kka2,kka2_1:8,P00552,0.73211,NO,236,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-1.363,-4.78,3.417,,0.303,H,A,1.51,-0.76,1.87,,48.48,AHH,-1.81267,0.100394,0.0088796,0.73211 kka2_1:8_W236H,kka2_1:8_236,Kka2,kka2_1:8,P00552,0.73211,NO,236,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-1.363,-4.78,3.417,,0.303,H,A,1.51,-0.76,1.87,,48.48,AHH,-1.81267,0.100394,0.0088796,0.73211 beta-lactamase_0_L192P,beta-lactamase_0_192,TEM-1,beta-lactamase_0,P62593,0.732197,NO,192,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.254,-4.129,2.875,,0.095,H,A,0.55,0.35,1.756,,60.14,HHP,-1.41833,0.0500837,0.00558728,0.732197 beta-lactamase_0_D177K,beta-lactamase_0_177,TEM-1,beta-lactamase_0,P62593,0.732259,NO,177,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.967,-3.523,2.556,,0.006,T,L,0.75,-1.02,3.536,,64.69,BAP,-0.873667,0.0500837,0.000864022,0.732259 beta-lactamase_L120V,beta-lactamase_120,TEM-1,beta-lactamase,P62593,0.732341,NO,120,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.044,-3.031,1.987,5.11974,,H,A,1.3,-1.13,1.988,,64.69,AHO,-1.13633,0.221079,0.00143563,0.732341 beta-lactamase_156_V42H,beta-lactamase_156_42,TEM-1,beta-lactamase_156,P62593,0.732387,NO,42,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.564,-4.991,3.427,,0.017,E,B,0.44,-0.51,2.576,,63.99,BHO,-1.042,0.111618,0.00404515,0.732387 beta-lactamase_0_A215L,beta-lactamase_0_215,TEM-1,beta-lactamase_0,P62593,0.732442,NO,215,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.503,-3.475,1.972,,,,a,0.46,-0.93,0.494,,74.48,HHO,-1.42633,0.0500837,0.00544007,0.732442 beta-lactamase_625_L89C,beta-lactamase_625_89,TEM-1,beta-lactamase_625,P62593,0.732515,NO,89,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.096,-4.756,3.66,,0.168,T,A,0.55,0.63,1.599,,64.34,PHO,-1.75767,0.213352,0.00207068,0.732515 kka2_1:2_G30C,kka2_1:2_30,Kka2,kka2_1:2,P00552,0.732582,NO,30,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.596,-5.115,4.519,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.295029,0.00159208,0.732582 beta-lactamase_0_V31A,beta-lactamase_0_31,TEM-1,beta-lactamase_0,P62593,0.732744,NO,31,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.822,-2.265,0.443,,,H,A,0.44,-0.46,4.126,,73.78,BHB,-2.03767,0.0500837,0.00478065,0.732744 gb1_E282Y,gb1_282,gb1,gb1,P06654,0.73277,NO,282,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.318,,,,,,,,,1.075,,35.71,PAO,-1.573,0.177985,0.00209643,0.73277 kka2_1:2_G21V,kka2_1:2_21,Kka2,kka2_1:2,P00552,0.732799,NO,21,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.368,-3.817,2.449,,0.586,T,l,0.29,-0.75,2.026,,71.59,HOH,-2.10167,0.295029,0.00709648,0.732799 beta-lactamase_0_T178N,beta-lactamase_0_178,TEM-1,beta-lactamase_0,P62593,0.732802,NO,178,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-0.791,-3.448,2.657,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.0500837,0.000684366,0.732802 kka2_1:4_I228T,kka2_1:4_228,Kka2,kka2_1:4,P00552,0.732802,NO,228,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.142,-3.482,2.34,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.168804,0.00458834,0.732802 kka2_1:4_G213C,kka2_1:4_213,Kka2,kka2_1:4,P00552,0.732825,NO,213,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.596,-5.115,4.519,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.168804,0.00187654,0.732825 kka2_1:2_L103H,kka2_1:2_103,Kka2,kka2_1:2,P00552,0.732872,NO,103,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-2.362,-4.862,2.5,,0.394,T,A,0.55,-0.99,3.499,,63.64,HHP,-1.534,0.295029,0.00574792,0.732872 beta-lactamase_0_R63W,beta-lactamase_0_63,TEM-1,beta-lactamase_0,P62593,0.732873,NO,63,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-0.943,-5.32,4.377,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.0500837,0.00126938,0.732873 kka2_1:2_A41L,kka2_1:2_41,Kka2,kka2_1:2,P00552,0.733026,NO,41,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.879,-3.033,1.154,,0.184,.,B,0.46,-0.96,24.451,24.451,64.39,PHP,-2.477,0.295029,0.00543332,0.733026 beta-lactamase_0_K254V,beta-lactamase_0_254,TEM-1,beta-lactamase_0,P62593,0.733086,NO,254,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.0500837,0.00369,0.733086 beta-lactamase_L100K,beta-lactamase_100,TEM-1,beta-lactamase,P62593,0.733109,NO,100,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.218,-3.837,2.619,5.60291,0.343,,B,1.3,0.13,1.173,,63.29,AHH,-1.23467,0.221079,0.00413885,0.733109 kka2_1:2_C192I,kka2_1:2_192,Kka2,kka2_1:2,P00552,0.733263,NO,192,C,I,CI,Special,Hydrophobic,5.07,6.02,0.95,198,121,131,10,108.5,166.7,58.2,-1.067,-3.687,2.62,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.295029,0.00485428,0.733263 kka2_1:1_G21C,kka2_1:1_21,Kka2,kka2_1:1,P00552,0.733293,NO,21,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.368,-5.139,3.771,,0.586,T,l,0.29,-0.75,10.291,10.291,71.59,HOH,-2.10167,0.520039,0.00709648,0.733293 beta-lactamase_2500_A170R,beta-lactamase_2500_170,TEM-1,beta-lactamase_2500,P62593,0.733528,NO,170,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.237,-3.908,2.671,,0.126,,L,0.46,-0.35,2.427,,64.69,AHH,-1.63267,0.361275,0.00431903,0.733528 beta-lactamase_L191W,beta-lactamase_191,TEM-1,beta-lactamase,P62593,0.733588,NO,191,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.087,-5.14,4.053,5.72226,,H,A,1.07,0.09,1.23,,63.29,BHH,-1.445,0.221079,0.00263549,0.733588 gb1_Y259A,gb1_259,gb1,gb1,P06654,0.733614,NO,259,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-1.78,-3.22,1.44,,,,,,,0.131,,11.83,PHH,-1.787,0.177985,0.00464313,0.733614 beta-lactamase_G52R,beta-lactamase_52,TEM-1,beta-lactamase,P62593,0.733712,NO,52,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.149,-3.956,2.807,5.12093,0.299,,l,0.77,-0.04,2.103,,64.69,POB,-1.66267,0.221079,0.00340138,0.733712 beta-lactamase_156_A123D,beta-lactamase_156_123,TEM-1,beta-lactamase_156,P62593,0.733815,NO,123,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.834,-3.743,2.909,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.111618,0.0010157,0.733815 kka2_1:1_A79I,kka2_1:1_79,Kka2,kka2_1:1,P00552,0.733838,NO,79,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.368,-3.11,0.742,,0.563,.,B,0.46,-0.43,7.792,7.792,71.59,HHH,-1.752,0.520039,0.00664821,0.733838 kka2_1:2_W91C,kka2_1:2_91,Kka2,kka2_1:2,P00552,0.733848,NO,91,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-1.178,-5.004,3.826,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.295029,0.00358653,0.733848 beta-lactamase_2500_G253W,beta-lactamase_2500_253,TEM-1,beta-lactamase_2500,P62593,0.73385,NO,253,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.361275,0.00786358,0.73385 Ubiquitin_D21R,Ubiquitin_21,Uba1,Ubiquitin,P0CG48,0.733871,NO,21,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.193,-3.843,2.65,4.96432,0.165,,B,0.23,-0.53,1.013,,71.82,PAP,-1.35867,0.205827,0.000465257,0.733871 Ubiquitin_I61E,Ubiquitin_61,Uba1,Ubiquitin,P0CG48,0.733871,NO,61,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.514,-3.806,2.292,5.19922,0.038,,B,1,-0.76,1.953,,24.53,PHP,-1.70833,0.205827,0.000738268,0.733871 Ubiquitin_K27F,Ubiquitin_27,Uba1,Ubiquitin,P0CG48,0.733871,NO,27,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.064,-4.292,3.228,4.77438,0.086,H,A,2.89,-0.74,2.662,,27.01,HBH,-1.42667,0.205827,0.000767556,0.733871 Ubiquitin_R72S,Ubiquitin_72,Uba1,Ubiquitin,P0CG48,0.733871,NO,72,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.034,-2.87,0.836,5.19484,0.077,,B,1.41,-0.1,9.638,9.638,42.77,HBH,-1.82733,0.205827,0.000768249,0.733871 Ubiquitin_T66E,Ubiquitin_66,Uba1,Ubiquitin,P0CG48,0.733871,NO,66,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.58,-3.612,2.032,5.02702,0.46,E,B,0.8,-0.81,28.36,28.36,39.71,PPH,-1.51667,0.205827,0.000598414,0.733871 beta-lactamase_156_R159D,beta-lactamase_156_159,TEM-1,beta-lactamase_156,P62593,0.733886,NO,159,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-0.94,-3.691,2.751,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.111618,0.00108472,0.733886 beta-lactamase_G234M,beta-lactamase_234,TEM-1,beta-lactamase,P62593,0.734014,NO,234,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.62,-4.93,4.31,4.24221,0.023,E,B,0.46,-0.86,,,,POH,-1.25733,0.221079,0.000889577,0.734014 beta-lactamase_P105N,beta-lactamase_105,TEM-1,beta-lactamase,P62593,0.734014,NO,105,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.813,-3.82,3.007,5.08236,0.226,T,A,0.98,0.8,1.154,,63.29,POH,-1.01533,0.221079,0.0011981,0.734014 beta-lactamase_R241T,beta-lactamase_241,TEM-1,beta-lactamase,P62593,0.734022,NO,241,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.433,-2.293,0.86,5.02621,0.094,E,B,0.68,-0.16,1.327,,50,PBO,-1.42967,0.221079,0.00452736,0.734022 kka2_1:2_W91L,kka2_1:2_91,Kka2,kka2_1:2,P00552,0.734132,NO,91,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-1.178,-3.365,2.187,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.295029,0.00358653,0.734132 beta-lactamase_F228G,beta-lactamase_228,TEM-1,beta-lactamase,P62593,0.734218,NO,228,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-2.342,-3.572,1.23,5.33448,0.154,E,B,1.1,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.221079,0.0046669,0.734218 beta-lactamase_0_A230V,beta-lactamase_0_230,TEM-1,beta-lactamase_0,P62593,0.734226,NO,230,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.154,-3.38,2.226,,0.01,E,B,0.46,-1.17,2.179,,50,HHA,-1.079,0.0500837,0.00516841,0.734226 beta-lactamase_0_W208Y,beta-lactamase_0_208,TEM-1,beta-lactamase_0,P62593,0.734232,NO,208,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-0.818,-3.262,2.444,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.0500837,0.00126609,0.734232 beta-lactamase_0_L150Q,beta-lactamase_0_150,TEM-1,beta-lactamase_0,P62593,0.734359,NO,150,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.326,-4.106,2.78,,,H,A,0.55,-0.2,2.128,,62.94,HHB,-1.86167,0.0500837,0.00463171,0.734359 kka2_1:2_W236L,kka2_1:2_236,Kka2,kka2_1:2,P00552,0.73438,NO,236,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-1.363,-2.199,0.836,,0.303,H,A,1.51,-0.76,5.58,,48.48,AHH,-1.81267,0.295029,0.0088796,0.73438 gb1_N263R,gb1_263,gb1,gb1,P06654,0.734455,NO,263,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-1.162,-3.26,2.098,,,,,,,,,,APO,-2.04233,0.177985,0.0035297,0.734455 kka2_1:1_L223P,kka2_1:1_223,Kka2,kka2_1:1,P00552,0.734461,NO,223,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.861,-4.178,3.317,,,H,A,0.55,-1.24,1.268,,50,HHH,-0.854333,0.520039,0.00253574,0.734461 kka2_1:2_D250A,kka2_1:2_250,Kka2,kka2_1:2,P00552,0.734465,NO,250,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.015,-3.315,2.3,,0.274,.,b,0.75,-0.46,3.796,,51.89,OAP,-1.83933,0.295029,0.0177103,0.734465 Pab1_K131S,Pab1_131,Pab1,Pab1,P04147,0.73457,NO,131,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.083,-2.978,1.895,,0.462,E,B,1.82,0.57,,,,HBP,-1.12467,0.175299,0.000349395,0.73457 kka2_1:2_Y22C,kka2_1:2_22,Kka2,kka2_1:2,P00552,0.734624,NO,22,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-1.583,-3.399,1.816,,0.122,.,B,0.21,-0.8,1.838,,65.53,OHA,-1.80333,0.295029,0.00598977,0.734624 beta-lactamase_A215P,beta-lactamase_215,TEM-1,beta-lactamase,P62593,0.734671,NO,215,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.503,-3.85,2.347,4.82164,,,a,0.75,-0.93,3.583,,74.48,HHO,-1.42633,0.221079,0.00544007,0.734671 beta-lactamase_625_T178V,beta-lactamase_625_178,TEM-1,beta-lactamase_625,P62593,0.734673,NO,178,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-0.791,-3.079,2.288,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.213352,0.000684366,0.734673 beta-lactamase_0_R81Q,beta-lactamase_0_81,TEM-1,beta-lactamase_0,P62593,0.734698,NO,81,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.466,-2.446,0.98,,0.218,H,A,1.2,1.66,0.332,,50,PBH,-1.60667,0.0500837,0.00499763,0.734698 beta-lactamase_2500_G253V,beta-lactamase_2500_253,TEM-1,beta-lactamase_2500,P62593,0.734744,NO,253,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.361275,0.00786358,0.734744 beta-lactamase_39_S241I,beta-lactamase_39_241,TEM-1,beta-lactamase_39,P62593,0.734908,NO,241,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.0495842,0.00452736,0.734908 kka2_1:4_D154Y,kka2_1:4_154,Kka2,kka2_1:4,P00552,0.735053,NO,154,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.876,-4.417,3.541,,0.457,,b,0.29,1.48,15.641,15.641,52.65,HAP,-1.52467,0.168804,0.00292633,0.735053 beta-lactamase_2500_L47T,beta-lactamase_2500_47,TEM-1,beta-lactamase_2500,P62593,0.735065,NO,47,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.876,-2.727,0.851,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.361275,0.00439844,0.735065 beta-lactamase_39_M66W,beta-lactamase_39_66,TEM-1,beta-lactamase_39,P62593,0.735159,NO,66,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.362,-5.087,3.725,,0.013,,A,0.55,-0.7,1.319,,73.08,OHH,-1.49567,0.0495842,0.00412876,0.735159 beta-lactamase_0_L89T,beta-lactamase_0_89,TEM-1,beta-lactamase_0,P62593,0.735182,NO,89,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.096,-3.474,2.378,,0.168,T,A,0.55,0.63,2.373,,64.34,PHO,-1.75767,0.0500837,0.00207068,0.735182 beta-lactamase_625_P105W,beta-lactamase_625_105,TEM-1,beta-lactamase_625,P62593,0.735234,NO,105,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.813,-5.545,4.732,,0.226,T,A,0.52,0.8,1.154,,63.29,POH,-1.01533,0.213352,0.0011981,0.735234 PSD95pdz3_I327M,PSD95pdz3_327,PSD95pdz3,PSD95pdz3,P31016,0.735292,NO,327,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.63,-3.712,2.082,5.7413,,,,,14.0388,,,,PHH,-1.50167,0.0758425,0.000998774,0.735292 beta-lactamase_L223Q,beta-lactamase_223,TEM-1,beta-lactamase,P62593,0.735307,NO,223,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.055,-4.184,3.129,5.42318,0.27,,B,1.3,0.09,1.511,,74.48,HHO,-1.35033,0.221079,0.00372793,0.735307 beta-lactamase_0_L89Y,beta-lactamase_0_89,TEM-1,beta-lactamase_0,P62593,0.735355,NO,89,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.096,-4.101,3.005,,0.168,T,A,0.55,0.63,2.373,,64.34,PHO,-1.75767,0.0500837,0.00207068,0.735355 kka2_1:1_I115T,kka2_1:1_115,Kka2,kka2_1:1,P00552,0.735362,NO,115,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.606,-3.564,1.958,,0.105,H,A,0.48,-1.18,0.878,,65.53,PHH,-2.205,0.520039,0.00836567,0.735362 kka2_1:8_A224S,kka2_1:8_224,Kka2,kka2_1:8,P00552,0.7354,NO,224,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.977,-3.088,2.111,,,H,A,0.46,-1.26,0.357,,63.64,HHP,-1.41033,0.100394,0.00352047,0.7354 kka2_1:8_A224S,kka2_1:8_224,Kka2,kka2_1:8,P00552,0.7354,NO,224,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.977,-3.088,2.111,,,H,A,0.46,-1.26,0.357,,63.64,HHP,-1.41033,0.100394,0.00352047,0.7354 beta-lactamase_0_W208Q,beta-lactamase_0_208,TEM-1,beta-lactamase_0,P62593,0.735756,NO,208,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-0.818,-4.124,3.306,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.0500837,0.00126609,0.735756 kka2_1:2_A117E,kka2_1:2_117,Kka2,kka2_1:2,P00552,0.735793,NO,117,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.828,-3.532,2.704,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.295029,0.00282984,0.735793 kka2_1:2_F256L,kka2_1:2_256,Kka2,kka2_1:2,P00552,0.735839,NO,256,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.49,-3.235,1.745,,,H,A,0.58,-0.78,1.653,,53.03,HHH,-1.423,0.295029,0.0132841,0.735839 kka2_1:2_F240R,kka2_1:2_240,Kka2,kka2_1:2,P00552,0.735892,NO,240,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-0.911,-4.185,3.274,,,H,A,0.58,-1.21,0.373,,50.38,BHH,-1.67267,0.295029,0.00552543,0.735892 beta-lactamase_625_G236D,beta-lactamase_625_236,TEM-1,beta-lactamase_625,P62593,0.736032,NO,236,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.784,-3.513,2.729,,0.241,,b,0.29,-0.59,3.506,,64.69,HOO,-1.025,0.213352,0.00162372,0.736032 Pab1_S155M,Pab1_155,Pab1,Pab1,P04147,0.736083,NO,155,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.039,-4.315,2.276,,,,,,,,,,PPB,-1.42267,0.175299,0.00208179,0.736083 kka2_1:1_E3G,kka2_1:1_3,Kka2,kka2_1:1,P00552,0.73609,NO,3,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.199,-2.062,-0.137,,,,,,,3.435,,92.05,HAP,-2.11567,0.520039,0.00267607,0.73609 kka2_1:1_L92M,kka2_1:1_92,Kka2,kka2_1:1,P00552,0.736091,NO,92,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.893,-2.898,2.005,,0.007,E,B,0.55,-0.19,1.447,,63.26,HHH,-0.962,0.520039,0.00307177,0.736091 beta-lactamase_0_G52H,beta-lactamase_0_52,TEM-1,beta-lactamase_0,P62593,0.736093,NO,52,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.149,-4.712,3.563,,0.299,,l,0.29,-0.04,1.164,,64.69,POB,-1.66267,0.0500837,0.00340138,0.736093 kka2_1:8_D183P,kka2_1:8_183,Kka2,kka2_1:8,P00552,0.736108,NO,183,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.204,-3.861,2.657,,0.518,.,b,0.75,0.25,0.347,,52.27,AAH,-1.40533,0.100394,0.00426304,0.736108 kka2_1:8_D183P,kka2_1:8_183,Kka2,kka2_1:8,P00552,0.736108,NO,183,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.204,-3.861,2.657,,0.518,.,b,0.75,0.25,0.347,,52.27,AAH,-1.40533,0.100394,0.00426304,0.736108 beta-lactamase_625_T116Y,beta-lactamase_625_116,TEM-1,beta-lactamase_625,P62593,0.736115,NO,116,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.28,-4.295,3.015,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.213352,0.00336175,0.736115 gb1_V280N,gb1_280,gb1,gb1,P06654,0.736122,NO,280,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.764,-3.898,2.134,,,,,,,0.874,,35.71,PHP,-1.63733,0.177985,0.00321577,0.736122 kka2_1:4_G201M,kka2_1:4_201,Kka2,kka2_1:4,P00552,0.736124,NO,201,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.56,-4.972,3.412,,0.149,T,l,0.29,-0.57,0.284,,52.65,POB,-1.92233,0.168804,0.00820117,0.736124 beta-lactamase_0_V31N,beta-lactamase_0_31,TEM-1,beta-lactamase_0,P62593,0.73615,NO,31,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.822,-4.194,2.372,,,H,A,0.44,-0.46,4.126,,73.78,BHB,-2.03767,0.0500837,0.00478065,0.73615 beta-lactamase_G239N,beta-lactamase_239,TEM-1,beta-lactamase,P62593,0.736168,NO,239,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.819,-2.55,1.731,4.85529,0.115,T,l,0.77,-0.62,1.817,,42.31,BOP,-1.45267,0.221079,0.00213852,0.736168 beta-lactamase_0_H156N,beta-lactamase_0_156,TEM-1,beta-lactamase_0,P62593,0.736176,NO,156,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-3.156,-2.52,-0.636,,0.753,S,A,0.17,-0.6,23.367,23.367,77.62,ABH,-1.932,0.0500837,0.00468596,0.736176 beta-lactamase_0_K254C,beta-lactamase_0_254,TEM-1,beta-lactamase_0,P62593,0.736239,NO,254,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.0500837,0.00369,0.736239 beta-lactamase_2500_G226C,beta-lactamase_2500_226,TEM-1,beta-lactamase_2500,P62593,0.736306,NO,226,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.461,-3.342,1.881,,0.701,T,l,0.29,-0.25,5.086,,74.48,HOH,-1.42933,0.361275,0.00665294,0.736306 beta-lactamase_0_C121F,beta-lactamase_0_121,TEM-1,beta-lactamase_0,P62593,0.736308,NO,121,C,F,CF,Special,Hydrophobic,5.07,3.32051,-1.74949,205,121,165,44,108.5,189.9,81.4,-0.953,-4.116,3.163,,,H,A,0.46,-0.81,3.302,,63.29,HOP,-1.46767,0.0500837,0.000744322,0.736308 kka2_1:8_G233L,kka2_1:8_233,Kka2,kka2_1:8,P00552,0.736429,NO,233,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.748,-3.881,3.133,,0.172,,b,0.75,-0.27,1.134,,49.24,HOO,-1.72067,0.100394,0.00232366,0.736429 kka2_1:8_G233L,kka2_1:8_233,Kka2,kka2_1:8,P00552,0.736429,NO,233,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.748,-3.881,3.133,,0.172,,b,0.75,-0.27,1.134,,49.24,HOO,-1.72067,0.100394,0.00232366,0.736429 kka2_1:1_Q163R,kka2_1:1_163,Kka2,kka2_1:1,P00552,0.736499,NO,163,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.162,-2.527,0.365,,0.58,T,B,0.64,1.85,2.779,,64.02,BPO,-1.78333,0.520039,0.00719507,0.736499 beta-lactamase_2500_P250T,beta-lactamase_2500_250,TEM-1,beta-lactamase_2500,P62593,0.736519,NO,250,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.361275,0.00550899,0.736519 kka2_1:4_G74F,kka2_1:4_74,Kka2,kka2_1:4,P00552,0.736535,NO,74,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.18,-4.449,3.269,,0.621,T,l,0.75,0.2,1.032,,64.39,POH,-1.91667,0.168804,0.00587035,0.736535 beta-lactamase_0_D48S,beta-lactamase_0_48,TEM-1,beta-lactamase_0,P62593,0.736551,NO,48,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.101,-3.25,2.149,,0.189,E,B,0.75,0.21,17.825,17.825,50.35,HAH,-1.62467,0.0500837,0.0027273,0.736551 kka2_1:2_D52N,kka2_1:2_52,Kka2,kka2_1:2,P00552,0.736552,NO,52,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.271,-3.474,1.203,,0.22,E,B,0.75,0.8,1.123,,71.59,PAH,-2.38367,0.295029,0.00175694,0.736552 kka2_1:1_D180T,kka2_1:1_180,Kka2,kka2_1:1,P00552,0.736713,NO,180,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.416,-3.001,0.585,,1.03,S,a,0.75,1.5,1.534,,71.59,OAO,-2.02933,0.520039,0.00756412,0.736713 kka2_1:1_G55C,kka2_1:1_55,Kka2,kka2_1:1,P00552,0.73677,NO,55,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.625,-5.134,3.509,,0.517,S,b,0.29,1.19,4.035,,63.64,POH,-2.05967,0.520039,0.00667877,0.73677 beta-lactamase_0_T139V,beta-lactamase_0_139,TEM-1,beta-lactamase_0,P62593,0.736798,NO,139,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.901,-3.468,1.567,,0.216,H,A,0.22,0.39,0.421,,77.62,PPH,-2.04667,0.0500837,0.00441837,0.736798 beta-lactamase_2500_L28H,beta-lactamase_2500_28,TEM-1,beta-lactamase_2500,P62593,0.736814,NO,28,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.579,-4.838,3.259,,0.277,H,A,0.55,-0.16,2.716,,93.01,PHH,-2.11333,0.361275,0.00359321,0.736814 kka2_1:8_G210P,kka2_1:8_210,Kka2,kka2_1:8,P00552,0.736832,NO,210,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.095,-3.953,2.858,,0.103,T,A,0.75,-0.62,2.687,,50,OOB,-0.966667,0.100394,0.00598378,0.736832 kka2_1:8_G210P,kka2_1:8_210,Kka2,kka2_1:8,P00552,0.736832,NO,210,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.095,-3.953,2.858,,0.103,T,A,0.75,-0.62,2.687,,50,OOB,-0.966667,0.100394,0.00598378,0.736832 kka2_1:8_D62F,kka2_1:8_62,Kka2,kka2_1:8,P00552,0.736868,NO,62,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.591,-4.401,2.81,,0.262,H,A,0.29,0.08,5.58,,64.39,PAA,-1.77833,0.100394,0.00744243,0.736868 kka2_1:8_D62F,kka2_1:8_62,Kka2,kka2_1:8,P00552,0.736868,NO,62,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.591,-4.401,2.81,,0.262,H,A,0.29,0.08,5.58,,64.39,PAA,-1.77833,0.100394,0.00744243,0.736868 beta-lactamase_156_I140R,beta-lactamase_156_140,TEM-1,beta-lactamase_156,P62593,0.736949,NO,140,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.733,-4.193,2.46,,0.128,H,A,0.48,0.41,1.16,,73.08,PHO,-1.48733,0.111618,0.00597777,0.736949 gb1_K254L,gb1_254,gb1,gb1,P06654,0.73695,NO,254,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.748,-3.302,1.554,,,,,,,1.793,,37.28,ABH,-2.195,0.177985,0.00622711,0.73695 beta-lactamase_2500_K213W,beta-lactamase_2500_213,TEM-1,beta-lactamase_2500,P62593,0.737025,NO,213,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.81,-5.386,3.576,,0.67,,A,2.34,0.29,1.668,,67.83,ABH,-1.57767,0.361275,0.00610411,0.737025 beta-lactamase_0_G154H,beta-lactamase_0_154,TEM-1,beta-lactamase_0,P62593,0.737045,NO,154,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.823,-4.704,3.881,,0.54,T,l,0.29,-0.56,3.629,,64.69,HOA,-1.635,0.0500837,0.00180205,0.737045 beta-lactamase_R202Y,beta-lactamase_202,TEM-1,beta-lactamase,P62593,0.737181,NO,202,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.292,-4.182,2.89,5.16273,0.188,H,A,0.68,0.62,1.918,,77.62,PBP,-1.54767,0.221079,0.00321899,0.737181 beta-lactamase_2500_Y262I,beta-lactamase_2500_262,TEM-1,beta-lactamase_2500,P62593,0.737189,NO,262,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.361275,0.00853516,0.737189 kka2_1:1_R145K,kka2_1:1_145,Kka2,kka2_1:1,P00552,0.737239,NO,145,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.804,-2.124,0.32,,0.346,H,A,1.2,1.23,23.699,23.699,63.64,HBP,-1.88033,0.520039,0.00846663,0.737239 Pab1_F173I,Pab1_173,Pab1,Pab1,P04147,0.737267,NO,173,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.477,-3.318,1.841,,,E,B,0.87,-0.16,1.636,,63.26,BHA,-1.36967,0.175299,0.00148779,0.737267 beta-lactamase_156_R242F,beta-lactamase_156_242,TEM-1,beta-lactamase_156,P62593,0.737366,NO,242,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.111618,0.00452879,0.737366 beta-lactamase_156_F228D,beta-lactamase_156_228,TEM-1,beta-lactamase_156,P62593,0.737388,NO,228,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-2.342,-3.807,1.465,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.111618,0.0046669,0.737388 kka2_1:1_L81P,kka2_1:1_81,Kka2,kka2_1:1,P00552,0.737446,NO,81,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.427,-4.19,2.763,,0.46,E,A,0.55,-0.14,0.374,,63.64,HHA,-1.50567,0.520039,0.00805839,0.737446 kka2_1:2_P128L,kka2_1:2_128,Kka2,kka2_1:2,P00552,0.737455,NO,128,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.922,-2.383,0.461,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.295029,0.00774689,0.737455 kka2_1:2_P132Q,kka2_1:2_132,Kka2,kka2_1:2,P00552,0.737549,NO,132,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.775,-3.926,3.151,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.295029,0.0018489,0.737549 beta-lactamase_0_S68K,beta-lactamase_0_68,TEM-1,beta-lactamase_0,P62593,0.737577,NO,68,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-0.913,-3.258,2.345,,0.064,G,A,0.27,-1.03,1.441,,64.69,HPP,-1.37233,0.0500837,0.000800065,0.737577 beta-lactamase_0_K53V,beta-lactamase_0_53,TEM-1,beta-lactamase_0,P62593,0.737638,NO,53,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-2.313,-3.678,1.365,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.0500837,0.00383383,0.737638 beta-lactamase_0_E108Q,beta-lactamase_0_108,TEM-1,beta-lactamase_0,P62593,0.73764,NO,108,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.46,-2.893,1.433,,0.572,G,A,1.04,1.87,8.602,8.602,72.73,PAB,-1.437,0.0500837,0.00413372,0.73764 kka2_1:2_G164T,kka2_1:2_164,Kka2,kka2_1:2,P00552,0.737691,NO,164,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.869,-3.578,2.709,,0.862,T,l,0.75,1.45,1.539,,64.39,POH,-1.828,0.295029,0.00442091,0.737691 kka2_1:2_K50T,kka2_1:2_50,Kka2,kka2_1:2,P00552,0.737694,NO,50,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-0.833,-3.473,2.64,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.295029,0.00138626,0.737694 kka2_1:2_F206V,kka2_1:2_206,Kka2,kka2_1:2,P00552,0.737696,NO,206,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.349,-2.691,1.342,,0.006,E,B,0.58,-1.21,0.978,,63.64,OHH,-1.04,0.295029,0.00936868,0.737696 PSD95pdz3_V362N,PSD95pdz3_362,PSD95pdz3,PSD95pdz3,P31016,0.737728,NO,362,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.465,-3.805,2.34,4.99436,,,,,19.6443,,,,PHP,-1.46467,0.0758425,0.000538527,0.737728 beta-lactamase_625_T69I,beta-lactamase_625_69,TEM-1,beta-lactamase_625,P62593,0.737761,NO,69,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-0.973,-3.64,2.667,,,G,A,0.22,-1.24,2.716,,93.01,PPH,-1.01833,0.213352,0.00127498,0.737761 gb1_G235L,gb1_235,gb1,gb1,P06654,0.737773,NO,235,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.419,-3.226,1.807,,,,,,,0.476,,11.83,POB,-1.86433,0.177985,0.00297491,0.737773 gb1_L238R,gb1_238,gb1,gb1,P06654,0.737773,NO,238,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-2.98,-3.299,0.319,,,,,,,0.504,,45.54,PHB,-2.58633,0.177985,0.00205885,0.737773 beta-lactamase_0_R176M,beta-lactamase_0_176,TEM-1,beta-lactamase_0,P62593,0.737933,NO,176,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-0.863,-4.48,3.617,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.0500837,0.00105554,0.737933 beta-lactamase_0_T186V,beta-lactamase_0_186,TEM-1,beta-lactamase_0,P62593,0.737995,NO,186,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.522,-3.557,1.035,,0.396,H,A,0.22,-0.28,16.606,16.606,77.62,HPP,-1.77633,0.0500837,0.00485034,0.737995 beta-lactamase_0_P255Y,beta-lactamase_0_255,TEM-1,beta-lactamase_0,P62593,0.738004,NO,255,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.0500837,0.00499612,0.738004 beta-lactamase_39_G249T,beta-lactamase_39_249,TEM-1,beta-lactamase_39,P62593,0.738041,NO,249,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.312,,,,0.256,S,B,0.23,0.04,30.841,30.841,72.73,HOO,-1.81367,0.0495842,0.00220169,0.738041 kka2_1:1_E199A,kka2_1:1_199,Kka2,kka2_1:1,P00552,0.738061,NO,199,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.234,-2.101,-0.133,,0.508,E,B,1.04,-0.43,3.012,,65.53,HAP,-2.133,0.520039,0.00854122,0.738061 beta-lactamase_2500_H24Y,beta-lactamase_2500_24,TEM-1,beta-lactamase_2500,P62593,0.738073,NO,24,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-2.481,-4.052,1.571,,,,,,,0.467,,93.01,OBO,-2.0035,0.361275,0.00238894,0.738073 beta-lactamase_V214W,beta-lactamase_214,TEM-1,beta-lactamase,P62593,0.738075,NO,214,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.299,-5.33,4.031,5.74008,0.375,S,A,1.19,-0.44,1.899,,74.48,BHH,-1.53733,0.221079,0.00628442,0.738075 kka2_1:1_A248S,kka2_1:1_248,Kka2,kka2_1:1,P00552,0.738118,NO,248,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.124,-2.844,0.72,,0.825,S,b,0.46,0.46,24.72,24.72,92.05,HHO,-2.15,0.520039,0.0125484,0.738118 beta-lactamase_39_V260D,beta-lactamase_39_260,TEM-1,beta-lactamase_39,P62593,0.738136,NO,260,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.0495842,0.00471757,0.738136 beta-lactamase_0_S68V,beta-lactamase_0_68,TEM-1,beta-lactamase_0,P62593,0.738197,NO,68,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-0.913,-3.578,2.665,,0.064,G,A,0.27,-1.03,1.441,,64.69,HPP,-1.37233,0.0500837,0.000800065,0.738197 beta-lactamase_2500_L38S,beta-lactamase_2500_38,TEM-1,beta-lactamase_2500,P62593,0.7382,NO,38,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.343,-2.597,1.254,,0.088,H,A,0.55,0.2,2.71,,64.34,PHO,-1.78033,0.361275,0.00373244,0.7382 beta-lactamase_0_K71R,beta-lactamase_0_71,TEM-1,beta-lactamase_0,P62593,0.738228,NO,71,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-0.8,-3.033,2.233,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.0500837,0.00103192,0.738228 beta-lactamase_P105F,beta-lactamase_105,TEM-1,beta-lactamase,P62593,0.738292,NO,105,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.813,-4.48,3.667,5.08236,0.226,T,A,0.98,0.8,1.154,,63.29,POH,-1.01533,0.221079,0.0011981,0.738292 kka2_1:8_L92Q,kka2_1:8_92,Kka2,kka2_1:8,P00552,0.73833,NO,92,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.893,-4.159,3.266,,0.007,E,B,1.59,-0.19,1.719,,63.26,HHH,-0.962,0.100394,0.00307177,0.73833 kka2_1:8_L92Q,kka2_1:8_92,Kka2,kka2_1:8,P00552,0.73833,NO,92,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.893,-4.159,3.266,,0.007,E,B,1.59,-0.19,1.719,,63.26,HHH,-0.962,0.100394,0.00307177,0.73833 kka2_1:8_V153G,kka2_1:8_153,Kka2,kka2_1:8,P00552,0.73833,NO,153,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.092,-3.674,2.582,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.100394,0.00501119,0.73833 kka2_1:8_V153G,kka2_1:8_153,Kka2,kka2_1:8,P00552,0.73833,NO,153,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.092,-3.674,2.582,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.100394,0.00501119,0.73833 kka2_1:1_T85A,kka2_1:1_85,Kka2,kka2_1:1,P00552,0.738387,NO,85,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.165,-2.833,0.668,,0.576,E,B,0.82,1.39,16.653,16.653,71.59,HPA,-2.10133,0.520039,0.00634493,0.738387 kka2_1:2_I254S,kka2_1:2_254,Kka2,kka2_1:2,P00552,0.738418,NO,254,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.933,-3.691,1.758,,0.135,H,A,1.52,-0.6,2.562,,71.59,BHH,-1.668,0.295029,0.0132375,0.738418 beta-lactamase_F58E,beta-lactamase_58,TEM-1,beta-lactamase,P62593,0.738445,NO,58,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-2.914,-3.579,0.665,5.55634,0.266,E,B,1.33,-0.07,2.467,,77.62,PHB,-2.059,0.221079,0.00523369,0.738445 beta-lactamase_E35G,beta-lactamase_35,TEM-1,beta-lactamase,P62593,0.738461,NO,35,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-0.869,-3.356,2.487,5.10723,0.15,H,A,0.52,0.21,1.081,,46.85,HAA,-1.88667,0.221079,0.00174441,0.738461 beta-lactamase_625_S266I,beta-lactamase_625_266,TEM-1,beta-lactamase_625,P62593,0.738464,NO,266,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.213352,0.0140785,0.738464 kka2_1:4_V153A,kka2_1:4_153,Kka2,kka2_1:4,P00552,0.738505,NO,153,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.092,-2.452,1.36,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.168804,0.00501119,0.738505 beta-lactamase_0_T158L,beta-lactamase_0_158,TEM-1,beta-lactamase_0,P62593,0.738553,NO,158,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.116,-3.303,2.187,,0.036,,B,0.22,-0.85,1.041,,69.58,HPB,-1.269,0.0500837,0.00341825,0.738553 beta-lactamase_K252P,beta-lactamase_252,TEM-1,beta-lactamase,P62593,0.738576,NO,252,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.94,-3.001,1.061,5.56823,0.766,,B,1.82,1.16,21.796,21.796,67.83,OBO,-2.03333,0.221079,0.00575769,0.738576 gb1_L238K,gb1_238,gb1,gb1,P06654,0.738591,NO,238,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-2.98,-2.058,-0.922,,,,,,,0.504,,45.54,PHB,-2.58633,0.177985,0.00205885,0.738591 kka2_1:4_L223M,kka2_1:4_223,Kka2,kka2_1:4,P00552,0.738594,NO,223,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.861,-3.916,3.055,,,H,A,1.59,-1.24,1.268,,50,HHH,-0.854333,0.168804,0.00253574,0.738594 kka2_1:8_A119M,kka2_1:8_119,Kka2,kka2_1:8,P00552,0.738595,NO,119,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.073,-4.566,3.493,,0.019,H,A,0.46,-0.57,1.511,,71.59,AHH,-2.34,0.100394,0.00441074,0.738595 kka2_1:8_A119M,kka2_1:8_119,Kka2,kka2_1:8,P00552,0.738595,NO,119,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.073,-4.566,3.493,,0.019,H,A,0.46,-0.57,1.511,,71.59,AHH,-2.34,0.100394,0.00441074,0.738595 kka2_1:8_W15Q,kka2_1:8_15,Kka2,kka2_1:8,P00552,0.738694,NO,15,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-1.392,-4.279,2.887,,0.01,G,A,1.51,0.15,0.827,,52.27,HHH,-2.10533,0.100394,0.00585505,0.738694 kka2_1:8_W15Q,kka2_1:8_15,Kka2,kka2_1:8,P00552,0.738694,NO,15,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-1.392,-4.279,2.887,,0.01,G,A,1.51,0.15,0.827,,52.27,HHH,-2.10533,0.100394,0.00585505,0.738694 beta-lactamase_0_S128D,beta-lactamase_0_128,TEM-1,beta-lactamase_0,P62593,0.738721,NO,128,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-0.84,-3.244,2.404,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.0500837,0.00071483,0.738721 beta-lactamase_0_T107L,beta-lactamase_0_107,TEM-1,beta-lactamase_0,P62593,0.738753,NO,107,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.117,-3.237,2.12,,,G,A,0.22,-0.06,3.73,,67.83,HPA,-1.265,0.0500837,0.00239347,0.738753 beta-lactamase_0_D36Q,beta-lactamase_0_36,TEM-1,beta-lactamase_0,P62593,0.738811,NO,36,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.732,-2.234,-0.498,,0.555,H,A,0.75,1.17,13.689,13.689,77.62,AAP,-1.91167,0.0500837,0.00476483,0.738811 beta-lactamase_2500_A34L,beta-lactamase_2500_34,TEM-1,beta-lactamase_2500,P62593,0.738812,NO,34,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.059,-2.191,0.132,,,H,A,0.46,-0.54,2.921,,73.78,AHA,-1.74967,0.361275,0.00407913,0.738812 kka2_1:2_P12Q,kka2_1:2_12,Kka2,kka2_1:2,P00552,0.738822,NO,12,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.853,-3.937,3.084,,,.,B,0.52,1.25,0.261,,48.11,POH,-1.80767,0.295029,0.00500011,0.738822 Pab1_K166D,Pab1_166,Pab1,Pab1,P04147,0.738825,NO,166,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.262,-3.429,2.167,,0.299,,l,,0,,,,PBO,-1.21033,0.175299,0.0011038,0.738825 kka2_1:1_A168V,kka2_1:1_168,Kka2,kka2_1:1,P00552,0.738851,NO,168,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.989,-3.131,1.142,,0.67,H,A,0.46,0.15,25.546,25.546,64.39,OHA,-2.12933,0.520039,0.00806773,0.738851 Pab1_K131A,Pab1_131,Pab1,Pab1,P04147,0.739042,NO,131,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.083,-2.895,1.812,,0.462,E,B,1.82,0.57,,,,HBP,-1.12467,0.175299,0.000349395,0.739042 beta-lactamase_0_G194C,beta-lactamase_0_194,TEM-1,beta-lactamase_0,P62593,0.739164,NO,194,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.396,-5.097,3.701,,0.276,S,b,0.29,0.36,3.017,,67.83,POA,-1.832,0.0500837,0.00392163,0.739164 beta-lactamase_T158G,beta-lactamase_158,TEM-1,beta-lactamase,P62593,0.739217,NO,158,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.116,-3.288,2.172,5.32011,0.036,,B,0.98,-0.85,2.755,,69.58,HPB,-1.269,0.221079,0.00341825,0.739217 beta-lactamase_156_K30P,beta-lactamase_156_30,TEM-1,beta-lactamase_156,P62593,0.739238,NO,30,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-2.307,-3.871,1.564,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.111618,0.00448593,0.739238 Pab1_L142Q,Pab1_142,Pab1,Pab1,P04147,0.739318,NO,142,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.039,-3.941,2.902,,0.007,H,A,0.84,-0.65,,,,HHH,-1.487,0.175299,0.000335477,0.739318 beta-lactamase_I93Q,beta-lactamase_93,TEM-1,beta-lactamase,P62593,0.739337,NO,93,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.401,-4.315,2.914,5.74695,0.128,E,B,0.77,0.44,1.757,,67.83,BHB,-1.873,0.221079,0.00527066,0.739337 kka2_1:4_P109Q,kka2_1:4_109,Kka2,kka2_1:4,P00552,0.739353,NO,109,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.412,-3.143,1.731,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.168804,0.0070929,0.739353 kka2_1:2_D250H,kka2_1:2_250,Kka2,kka2_1:2,P00552,0.739368,NO,250,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.015,-4.493,3.478,,0.274,.,b,0.75,-0.46,3.796,,51.89,OAP,-1.83933,0.295029,0.0177103,0.739368 beta-lactamase_0_V42P,beta-lactamase_0_42,TEM-1,beta-lactamase_0,P62593,0.73941,NO,42,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.564,-4.095,2.531,,0.017,E,B,0.44,-0.51,1.659,,63.99,BHO,-1.042,0.0500837,0.00404515,0.73941 beta-lactamase_0_L79I,beta-lactamase_0_79,TEM-1,beta-lactamase_0,P62593,0.739423,NO,79,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.842,-2.934,2.092,,0.007,H,A,0.55,-0.16,5.053,,50.35,HHP,-1.44333,0.0500837,0.000947397,0.739423 kka2_1:8_R258A,kka2_1:8_258,Kka2,kka2_1:8,P00552,0.739458,NO,258,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.626,-3.206,1.58,,0.316,H,A,0.16,-0.85,5.58,,53.03,HBH,-1.25933,0.100394,0.00983174,0.739458 kka2_1:8_R258A,kka2_1:8_258,Kka2,kka2_1:8,P00552,0.739458,NO,258,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.626,-3.206,1.58,,0.316,H,A,0.16,-0.85,5.58,,53.03,HBH,-1.25933,0.100394,0.00983174,0.739458 beta-lactamase_625_I93H,beta-lactamase_625_93,TEM-1,beta-lactamase_625,P62593,0.739476,NO,93,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.401,-5.004,3.603,,0.128,E,B,0.48,0.44,1.524,,67.83,BHB,-1.873,0.213352,0.00527066,0.739476 beta-lactamase_2500_L167T,beta-lactamase_2500_167,TEM-1,beta-lactamase_2500,P62593,0.739497,NO,167,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.138,-3.44,2.302,,0.015,G,A,0.55,-0.63,7.813,,64.69,AHP,-1.30767,0.361275,0.00303566,0.739497 beta-lactamase_R271P,beta-lactamase_271,TEM-1,beta-lactamase,P62593,0.739552,NO,271,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.249,-3.945,2.696,5.24516,0.085,H,A,1.67,-0.05,0.474,,63.99,ABP,-1.36633,0.221079,0.00752082,0.739552 kka2_1:8_G245V,kka2_1:8_245,Kka2,kka2_1:8,P00552,0.739567,NO,245,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.812,-3.749,2.937,,0.655,T,g,0.75,0.03,1.148,,65.53,HOH,-1.19833,0.100394,0.00683899,0.739567 kka2_1:8_G245V,kka2_1:8_245,Kka2,kka2_1:8,P00552,0.739567,NO,245,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.812,-3.749,2.937,,0.655,T,g,0.75,0.03,1.148,,65.53,HOH,-1.19833,0.100394,0.00683899,0.739567 kka2_1:2_S114I,kka2_1:2_114,Kka2,kka2_1:2,P00552,0.739682,NO,114,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.527,-3.933,1.406,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.295029,0.00705262,0.739682 kka2_1:2_P167R,kka2_1:2_167,Kka2,kka2_1:2,P00552,0.739714,NO,167,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-2.403,-4.046,1.643,,0.18,H,A,0.52,0.75,3.6,,64.39,HOH,-2.26633,0.295029,0.00543203,0.739714 kka2_1:1_T225N,kka2_1:1_225,Kka2,kka2_1:1,P00552,0.739723,NO,225,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.393,-4.009,1.616,,0.036,H,A,0.22,-1.22,4.554,,63.64,HPB,-1.58733,0.520039,0.0113598,0.739723 kka2_1:1_G88C,kka2_1:1_88,Kka2,kka2_1:1,P00552,0.739751,NO,88,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.689,-5.252,3.563,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.520039,0.00685559,0.739751 kka2_1:4_E96V,kka2_1:4_96,Kka2,kka2_1:4,P00552,0.739755,NO,96,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.573,-2.716,0.143,,0.476,,B,1.52,-0.65,1.254,,71.59,OAH,-2.143,0.168804,0.00369441,0.739755 kka2_1:4_T85P,kka2_1:4_85,Kka2,kka2_1:4,P00552,0.739777,NO,85,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.165,-4.057,1.892,,0.576,E,B,0.22,1.39,1.853,,71.59,HPA,-2.10133,0.168804,0.00634493,0.739777 kka2_1:4_R66K,kka2_1:4_66,Kka2,kka2_1:4,P00552,0.739802,NO,66,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-0.922,-2.125,1.203,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.168804,0.00161025,0.739802 kka2_1:1_I29T,kka2_1:1_29,Kka2,kka2_1:1,P00552,0.739815,NO,29,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.692,-2.952,1.26,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.520039,0.00619521,0.739815 kka2_1:2_G74C,kka2_1:2_74,Kka2,kka2_1:2,P00552,0.739859,NO,74,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.18,-5.237,4.057,,0.621,T,l,0.75,0.2,1.446,,64.39,POH,-1.91667,0.295029,0.00587035,0.739859 kka2_1:2_E235R,kka2_1:2_235,Kka2,kka2_1:2,P00552,0.739891,NO,235,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.955,-2.75,0.795,,0.631,H,A,1.04,0.12,26.048,26.048,65.53,OAH,-2.07267,0.295029,0.0102806,0.739891 beta-lactamase_625_D231H,beta-lactamase_625_231,TEM-1,beta-lactamase_625,P62593,0.739978,NO,231,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.816,-4.453,3.637,,,E,B,0.75,-1.06,1.025,,65.38,HAB,-0.994,0.213352,0.00107395,0.739978 beta-lactamase_0_T186R,beta-lactamase_0_186,TEM-1,beta-lactamase_0,P62593,0.74006,NO,186,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.522,-2.819,0.297,,0.396,H,A,0.22,-0.28,16.606,16.606,77.62,HPP,-1.77633,0.0500837,0.00485034,0.74006 beta-lactamase_2500_V214L,beta-lactamase_2500_214,TEM-1,beta-lactamase_2500,P62593,0.740121,NO,214,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.299,-2.237,0.938,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.361275,0.00628442,0.740121 kka2_1:4_W91R,kka2_1:4_91,Kka2,kka2_1:4,P00552,0.740134,NO,91,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-1.178,-2.437,1.259,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.168804,0.00358653,0.740134 kka2_1:1_G181R,kka2_1:1_181,Kka2,kka2_1:1,P00552,0.740138,NO,181,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-2.698,-2.623,-0.075,,0.379,S,B,0.75,0.78,15.356,15.356,71.59,AOA,-2.21,0.520039,0.00728319,0.740138 kka2_1:2_Q100I,kka2_1:2_100,Kka2,kka2_1:2,P00552,0.740161,NO,100,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.77,-3.068,0.298,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.295029,0.0066405,0.740161 beta-lactamase_2500_D99I,beta-lactamase_2500_99,TEM-1,beta-lactamase_2500,P62593,0.740235,NO,99,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.191,-3.979,2.788,,0.402,G,A,0.75,0.36,1.318,,64.69,PAH,-1.794,0.361275,0.00305446,0.740235 beta-lactamase_0_L120W,beta-lactamase_0_120,TEM-1,beta-lactamase_0,P62593,0.740261,NO,120,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.044,-5.142,4.098,,,H,A,0.55,-1.13,1.2,,64.69,AHO,-1.13633,0.0500837,0.00143563,0.740261 kka2_1:2_E231S,kka2_1:2_231,Kka2,kka2_1:2,P00552,0.740274,NO,231,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.002,-3.227,1.225,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.295029,0.00732383,0.740274 beta-lactamase_39_E195F,beta-lactamase_39_195,TEM-1,beta-lactamase_39,P62593,0.740378,NO,195,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.186,-4.475,2.289,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.0495842,0.00496565,0.740378 kka2_1:2_A108L,kka2_1:2_108,Kka2,kka2_1:2,P00552,0.740391,NO,108,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.061,-2.851,0.79,,0.243,.,B,0.46,-1.34,2.462,,71.59,HHO,-1.57033,0.295029,0.00751209,0.740391 kka2_1:4_R145C,kka2_1:4_145,Kka2,kka2_1:4,P00552,0.740476,NO,145,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.804,-5.218,3.414,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.168804,0.00846663,0.740476 kka2_1:1_V46M,kka2_1:1_46,Kka2,kka2_1:1,P00552,0.740483,NO,46,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-2.62,-3.643,1.023,,0.192,.,B,0.44,-1.12,20.149,20.149,92.05,OHH,-1.88633,0.520039,0.00631301,0.740483 beta-lactamase_625_G281F,beta-lactamase_625_281,TEM-1,beta-lactamase_625,P62593,0.740569,NO,281,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.213352,0.0406482,0.740569 kka2_1:1_R173E,kka2_1:1_173,Kka2,kka2_1:1,P00552,0.74058,NO,173,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.407,-1.731,-0.676,,0.308,H,A,0.16,-0.13,14.756,14.756,65.53,HBH,-1.70533,0.520039,0.00784999,0.74058 beta-lactamase_A235V,beta-lactamase_235,TEM-1,beta-lactamase,P62593,0.740748,NO,235,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.266,-2.665,1.399,4.83024,0.32,E,B,0.52,-0.86,1.344,,50,OHO,-0.89,0.221079,0.00493474,0.740748 beta-lactamase_0_I229S,beta-lactamase_0_229,TEM-1,beta-lactamase_0,P62593,0.740756,NO,229,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.267,-3.615,2.348,,0.083,E,B,0.48,-0.76,1.69,,50,HHH,-1.58767,0.0500837,0.00477249,0.740756 Pab1_A182F,Pab1_182,Pab1,Pab1,P04147,0.740813,NO,182,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.013,-3.884,2.871,,,H,A,0.17,0.79,,,,AHH,-1.36067,0.175299,0.000289034,0.740813 kka2_1:2_L57W,kka2_1:2_57,Kka2,kka2_1:2,P00552,0.740828,NO,57,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.898,-3.389,1.491,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.295029,0.00723769,0.740828 kka2_1:1_P12Q,kka2_1:1_12,Kka2,kka2_1:1,P00552,0.740867,NO,12,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.853,-3.937,3.084,,,.,B,0.52,1.25,0.261,,48.11,POH,-1.80767,0.520039,0.00500011,0.740867 kka2_1:2_H188N,kka2_1:2_188,Kka2,kka2_1:2,P00552,0.740875,NO,188,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-0.913,-3.295,2.382,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.295029,0.00273139,0.740875 beta-lactamase_G154T,beta-lactamase_154,TEM-1,beta-lactamase,P62593,0.74094,NO,154,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.823,-3.619,2.796,5.40944,0.54,T,l,0.77,-0.56,2.283,,64.69,HOA,-1.635,0.221079,0.00180205,0.74094 kka2_1:8_D127Y,kka2_1:8_127,Kka2,kka2_1:8,P00552,0.740944,NO,127,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.364,-4.502,3.138,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.100394,0.00660501,0.740944 kka2_1:8_D127Y,kka2_1:8_127,Kka2,kka2_1:8,P00552,0.740944,NO,127,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.364,-4.502,3.138,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.100394,0.00660501,0.740944 kka2_1:2_R38G,kka2_1:2_38,Kka2,kka2_1:2,P00552,0.740974,NO,38,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.207,-3.596,2.389,,0.355,E,B,1.2,-1.13,6.872,6.872,52.27,HBH,-1.28567,0.295029,0.00372499,0.740974 kka2_1:1_S105L,kka2_1:1_105,Kka2,kka2_1:1,P00552,0.741006,NO,105,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.945,-2.961,1.016,,0.056,S,B,0.27,-1.04,3.442,,65.53,PPB,-2.17033,0.520039,0.00847233,0.741006 beta-lactamase_2500_G265S,beta-lactamase_2500_265,TEM-1,beta-lactamase_2500,P62593,0.741014,NO,265,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.361275,0.00811926,0.741014 gb1_F256I,gb1_256,gb1,gb1,P06654,0.741023,NO,256,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.241,-3.112,1.871,,,,,,,,,,HHB,-2.04767,0.177985,0.00435993,0.741023 beta-lactamase_625_G142A,beta-lactamase_625_142,TEM-1,beta-lactamase_625,P62593,0.741024,NO,142,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.707,-2.85,2.143,,0.034,,p,0.29,-0.64,1.35,,64.69,OOO,-0.834,0.213352,0.00060149,0.741024 beta-lactamase_S240D,beta-lactamase_240,TEM-1,beta-lactamase,P62593,0.74106,NO,240,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.537,-3.492,1.955,4.75024,,,B,0.74,-0.74,0.357,,65.38,OPB,-1.263,0.221079,0.00591201,0.74106 beta-lactamase_39_G142I,beta-lactamase_39_142,TEM-1,beta-lactamase_39,P62593,0.741092,NO,142,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.707,-4.199,3.492,,0.034,,p,0.29,-0.64,1.947,,64.69,OOO,-0.834,0.0495842,0.00060149,0.741092 kka2_1:2_Y22F,kka2_1:2_22,Kka2,kka2_1:2,P00552,0.741121,NO,22,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-1.583,-3.718,2.135,,0.122,.,B,0.21,-0.8,1.838,,65.53,OHA,-1.80333,0.295029,0.00598977,0.741121 kka2_1:4_R147G,kka2_1:4_147,Kka2,kka2_1:4,P00552,0.741144,NO,147,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.123,-3.428,2.305,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.168804,0.00549168,0.741144 kka2_1:8_V113M,kka2_1:8_113,Kka2,kka2_1:8,P00552,0.741233,NO,113,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.233,-3.136,1.903,,0.008,H,A,1.48,-1.17,1.254,,52.27,BHP,-2.08367,0.100394,0.00650191,0.741233 kka2_1:8_V113M,kka2_1:8_113,Kka2,kka2_1:8,P00552,0.741233,NO,113,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.233,-3.136,1.903,,0.008,H,A,1.48,-1.17,1.254,,52.27,BHP,-2.08367,0.100394,0.00650191,0.741233 beta-lactamase_A23K,beta-lactamase_23,TEM-1,beta-lactamase,P62593,0.741253,NO,23,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.548,-3.595,2.047,,,,,,,0.801,,93.01,HHB,-2.235,0.221079,0.00245563,0.741253 beta-lactamase_L197R,beta-lactamase_197,TEM-1,beta-lactamase,P62593,0.741285,NO,197,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.853,-3.93,3.077,5.19172,0.007,S,B,1.3,0.33,1.756,,60.14,HHP,-1.833,0.221079,0.00144602,0.741285 Pab1_P200D,Pab1_200,Pab1,Pab1,P04147,0.741294,NO,200,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.871,-3.655,1.784,,,,,,,3.877,,80.59,HOO,-1.7005,0.175299,0.00190795,0.741294 beta-lactamase_0_K254E,beta-lactamase_0_254,TEM-1,beta-lactamase_0,P62593,0.741445,NO,254,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.0500837,0.00369,0.741445 kka2_1:1_P109Q,kka2_1:1_109,Kka2,kka2_1:1,P00552,0.741481,NO,109,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.412,-3.143,1.731,,0.376,H,A,0.52,-1.25,18.506,18.506,65.53,HOH,-1.84567,0.520039,0.0070929,0.741481 beta-lactamase_G226L,beta-lactamase_226,TEM-1,beta-lactamase,P62593,0.741506,NO,226,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.461,-3.765,2.304,5.70682,0.701,T,l,0.77,-0.25,3.199,,74.48,HOH,-1.42933,0.221079,0.00665294,0.741506 Pab1_G167D,Pab1_167,Pab1,Pab1,P04147,0.741519,NO,167,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.223,-3.502,2.279,,0.195,S,g,,0.03,,,,BOH,-1.25133,0.175299,0.00146449,0.741519 beta-lactamase_L89D,beta-lactamase_89,TEM-1,beta-lactamase,P62593,0.741574,NO,89,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.096,-3.996,2.9,5.41092,0.168,T,A,1.75,0.63,1.599,,64.34,PHO,-1.75767,0.221079,0.00207068,0.741574 kka2_1:1_E182Q,kka2_1:1_182,Kka2,kka2_1:1,P00552,0.741593,NO,182,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.516,-2.606,1.09,,0.326,,B,1.52,0.75,14.547,14.547,65.53,OAA,-1.806,0.520039,0.00641548,0.741593 beta-lactamase_R91L,beta-lactamase_91,TEM-1,beta-lactamase,P62593,0.741606,NO,91,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.392,-3.471,2.079,5.92536,0.444,,B,0.68,0.96,1.318,,50.35,OBB,-1.73367,0.221079,0.00380226,0.741606 beta-lactamase_625_L223Q,beta-lactamase_625_223,TEM-1,beta-lactamase_625,P62593,0.741668,NO,223,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.055,-4.184,3.129,,0.27,,B,0.55,0.09,1.633,,74.48,HHO,-1.35033,0.213352,0.00372793,0.741668 beta-lactamase_0_Y262M,beta-lactamase_0_262,TEM-1,beta-lactamase_0,P62593,0.741702,NO,262,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.0500837,0.00853516,0.741702 kka2_1:1_L152V,kka2_1:1_152,Kka2,kka2_1:1,P00552,0.741705,NO,152,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.521,-2.421,0.9,,0.547,.,A,0.55,1.36,1.589,,63.64,OHH,-1.162,0.520039,0.00674868,0.741705 beta-lactamase_625_M115S,beta-lactamase_625_115,TEM-1,beta-lactamase_625,P62593,0.741768,NO,115,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.389,-3.501,2.112,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.213352,0.0034337,0.741768 gb1_G240Q,gb1_240,gb1,gb1,P06654,0.741826,NO,240,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.921,-3.86,2.939,,,,,,,,,,BOA,-1.87867,0.177985,0.00270792,0.741826 Ubiquitin_D58I,Ubiquitin_58,Uba1,Ubiquitin,P0CG48,0.741935,NO,58,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.622,-2.713,1.091,5.06391,0.457,G,A,,-0.54,,,,PAH,-1.60267,0.205827,0.000639847,0.741935 Ubiquitin_E34I,Ubiquitin_34,Uba1,Ubiquitin,P0CG48,0.741935,NO,34,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.294,-3.88,2.586,5.02178,0.406,H,A,1.62,0.6,1.295,,35.62,BAO,-1.24933,0.205827,0.000686048,0.741935 Ubiquitin_I44M,Ubiquitin_44,Uba1,Ubiquitin,P0CG48,0.741935,NO,44,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.566,-3.058,1.492,4.71256,,E,B,0.27,-1.17,5.26,,39.71,HHH,-1.38567,0.205827,0.000613305,0.741935 Ubiquitin_K11V,Ubiquitin_11,Uba1,Ubiquitin,P0CG48,0.741935,NO,11,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.354,-3.445,2.091,5.16813,0.401,,B,2.81,0.84,0.335,,25.84,OBP,-1.346,0.205827,0.000535553,0.741935 Ubiquitin_K27M,Ubiquitin_27,Uba1,Ubiquitin,P0CG48,0.741935,NO,27,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.064,-4.527,3.463,4.77438,0.086,H,A,2.89,-0.74,2.662,,27.01,HBH,-1.42667,0.205827,0.000767556,0.741935 Ubiquitin_L56T,Ubiquitin_56,Uba1,Ubiquitin,P0CG48,0.741935,NO,56,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.324,-3.456,2.132,4.83362,,T,A,,-0.91,,,,PHP,-1.60067,0.205827,0.000459465,0.741935 beta-lactamase_39_M67R,beta-lactamase_39_67,TEM-1,beta-lactamase_39,P62593,0.741946,NO,67,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-2.231,-3.989,1.758,,0.006,G,P,0.55,-0.81,1.463,,65.03,HHP,-1.502,0.0495842,0.00409753,0.741946 kka2_1:4_R140L,kka2_1:4_140,Kka2,kka2_1:4,P00552,0.741983,NO,140,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.351,-3.517,2.166,,0.12,H,A,1.2,0.2,2.561,,53.03,BBH,-1.885,0.168804,0.00430167,0.741983 beta-lactamase_E56I,beta-lactamase_56,TEM-1,beta-lactamase,P62593,0.742024,NO,56,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.043,-3.825,1.782,5.65281,0.198,E,B,0.52,0.31,2.022,,72.73,HAP,-1.94033,0.221079,0.00238534,0.742024 kka2_1:2_E160G,kka2_1:2_160,Kka2,kka2_1:2,P00552,0.742086,NO,160,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.683,-3.367,1.684,,0.989,G,A,1.04,2.28,3.948,,71.59,AAA,-1.36133,0.295029,0.00935762,0.742086 kka2_1:8_F264M,kka2_1:8_264,Kka2,kka2_1:8,P00552,0.742099,NO,264,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.02,-4.352,3.332,,0.296,,?,1.62,0.02,1.553,,71.59,HHO,-0.9655,0.100394,,0.742099 kka2_1:8_F264M,kka2_1:8_264,Kka2,kka2_1:8,P00552,0.742099,NO,264,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.02,-4.352,3.332,,0.296,,?,1.62,0.02,1.553,,71.59,HHO,-0.9655,0.100394,,0.742099 kka2_1:4_G201L,kka2_1:4_201,Kka2,kka2_1:4,P00552,0.742105,NO,201,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.56,-3.824,2.264,,0.149,T,l,0.29,-0.57,0.284,,52.65,POB,-1.92233,0.168804,0.00820117,0.742105 kka2_1:1_A247E,kka2_1:1_247,Kka2,kka2_1:1,P00552,0.742108,NO,247,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.459,-2.615,0.156,,1.01,S,A,0.46,0.65,7.731,7.731,92.05,HHH,-2.197,0.520039,0.0102428,0.742108 kka2_1:2_L67R,kka2_1:2_67,Kka2,kka2_1:2,P00552,0.742132,NO,67,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.741,-3.961,3.22,,0.007,H,A,1.59,-0.66,,,,BHP,-1.42867,0.295029,0.00102787,0.742132 beta-lactamase_V21P,beta-lactamase_21,TEM-1,beta-lactamase,P62593,0.742171,NO,21,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.873,-3.814,1.941,,,,,,,0.688,,93.01,OHH,-2.09633,0.221079,0.0028612,0.742171 beta-lactamase_0_P217N,beta-lactamase_0_217,TEM-1,beta-lactamase_0,P62593,0.742185,NO,217,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-2.062,-2.997,0.935,,0.496,I,A,0.52,-0.33,1.087,,74.48,OOH,-1.64333,0.0500837,0.00463211,0.742185 kka2_1:2_E169N,kka2_1:2_169,Kka2,kka2_1:2,P00552,0.742185,NO,169,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.996,-3.126,1.13,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.295029,0.00730086,0.742185 kka2_1:1_Q4H,kka2_1:1_4,Kka2,kka2_1:1,P00552,0.742223,NO,4,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.361,-4.16,1.799,,,,,,,5.615,,71.59,APA,-1.95533,0.520039,0.00239179,0.742223 kka2_1:1_R211S,kka2_1:1_211,Kka2,kka2_1:1,P00552,0.742228,NO,211,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-0.899,-3.475,2.576,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.520039,0.00204888,0.742228 beta-lactamase_L79I,beta-lactamase_79,TEM-1,beta-lactamase,P62593,0.742235,NO,79,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.842,-2.934,2.092,4.98681,0.007,H,A,1.07,-0.16,0.823,,50.35,HHP,-1.44333,0.221079,0.000947397,0.742235 kka2_1:8_A117S,kka2_1:8_117,Kka2,kka2_1:8,P00552,0.742243,NO,117,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.828,-3.072,2.244,,,H,A,1.04,-0.78,0.755,,45.83,HHA,-1.79333,0.100394,0.00282984,0.742243 kka2_1:8_A117S,kka2_1:8_117,Kka2,kka2_1:8,P00552,0.742243,NO,117,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.828,-3.072,2.244,,,H,A,1.04,-0.78,0.755,,45.83,HHA,-1.79333,0.100394,0.00282984,0.742243 beta-lactamase_0_Q276G,beta-lactamase_0_276,TEM-1,beta-lactamase_0,P62593,0.742303,NO,276,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.0500837,0.0191712,0.742303 kka2_1:2_W15C,kka2_1:2_15,Kka2,kka2_1:2,P00552,0.74237,NO,15,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-1.392,-4.882,3.49,,0.01,G,A,0.47,0.15,2.586,,52.27,HHH,-2.10533,0.295029,0.00585505,0.74237 beta-lactamase_625_I140W,beta-lactamase_625_140,TEM-1,beta-lactamase_625,P62593,0.742383,NO,140,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.733,-5.289,3.556,,0.128,H,A,0.48,0.41,1.628,,73.08,PHO,-1.48733,0.213352,0.00597777,0.742383 kka2_1:2_G99C,kka2_1:2_99,Kka2,kka2_1:2,P00552,0.742432,NO,99,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.596,-5.115,4.519,,0.368,S,g,0.29,-0.87,,,,OOP,-1.63067,0.295029,0.00186055,0.742432 beta-lactamase_2500_E195M,beta-lactamase_2500_195,TEM-1,beta-lactamase_2500,P62593,0.742545,NO,195,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.186,-4.856,2.67,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.361275,0.00496565,0.742545 kka2_1:4_D82Q,kka2_1:4_82,Kka2,kka2_1:4,P00552,0.742569,NO,82,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.946,-2.981,1.035,,0.341,E,b,0.75,0.52,11.923,11.923,63.64,HAH,-1.98,0.168804,0.00637516,0.742569 kka2_1:4_I196R,kka2_1:4_196,Kka2,kka2_1:4,P00552,0.742603,NO,196,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-2.115,-4.247,2.132,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.168804,0.0107273,0.742603 gb1_L231Q,gb1_231,gb1,gb1,P06654,0.742625,NO,231,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.603,-3.816,2.213,,,,,,,0.219,,11.83,BHH,-1.82633,0.177985,0.00322797,0.742625 kka2_1:8_K50T,kka2_1:8_50,Kka2,kka2_1:8,P00552,0.742639,NO,50,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-0.833,-3.473,2.64,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.100394,0.00138626,0.742639 kka2_1:8_K50T,kka2_1:8_50,Kka2,kka2_1:8,P00552,0.742639,NO,50,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-0.833,-3.473,2.64,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.100394,0.00138626,0.742639 beta-lactamase_39_V259Q,beta-lactamase_39_259,TEM-1,beta-lactamase_39,P62593,0.742657,NO,259,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.0495842,0.0070773,0.742657 beta-lactamase_0_K71C,beta-lactamase_0_71,TEM-1,beta-lactamase_0,P62593,0.742667,NO,71,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-0.8,-5.087,4.287,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.0500837,0.00103192,0.742667 kka2_1:2_P128A,kka2_1:2_128,Kka2,kka2_1:2,P00552,0.742724,NO,128,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.922,-2.593,0.671,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.295029,0.00774689,0.742724 kka2_1:2_R143Y,kka2_1:2_143,Kka2,kka2_1:2,P00552,0.742793,NO,143,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.525,-4.353,1.828,,0.325,H,A,0.16,1.22,14.853,14.853,65.53,ABH,-1.86833,0.295029,0.00662247,0.742793 kka2_1:2_A129E,kka2_1:2_129,Kka2,kka2_1:2,P00552,0.742867,NO,129,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.656,-2.346,0.69,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.295029,0.00726862,0.742867 beta-lactamase_0_V42G,beta-lactamase_0_42,TEM-1,beta-lactamase_0,P62593,0.742953,NO,42,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.564,-2.773,1.209,,0.017,E,B,0.44,-0.51,1.659,,63.99,BHO,-1.042,0.0500837,0.00404515,0.742953 kka2_1:4_W24G,kka2_1:4_24,Kka2,kka2_1:4,P00552,0.742982,NO,24,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-1.779,-3.736,1.957,,0.477,E,B,1.51,-0.21,2.666,,56.06,AHH,-2.24467,0.168804,0.00631564,0.742982 PSD95pdz3_D348R,PSD95pdz3_348,PSD95pdz3,PSD95pdz3,P31016,0.74305,NO,348,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.264,-3.615,2.351,5.02473,,,,,16.8925,,,,HAH,-1.306,0.0758425,0.000731866,0.74305 beta-lactamase_0_V42L,beta-lactamase_0_42,TEM-1,beta-lactamase_0,P62593,0.743056,NO,42,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.564,-1.709,0.145,,0.017,E,B,0.44,-0.51,1.659,,63.99,BHO,-1.042,0.0500837,0.00404515,0.743056 beta-lactamase_0_D83G,beta-lactamase_0_83,TEM-1,beta-lactamase_0,P62593,0.743112,NO,83,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.066,-2.429,1.363,,0.354,H,A,0.75,0.22,0.617,,48.95,HAH,-1.34733,0.0500837,0.00205968,0.743112 kka2_1:1_G55V,kka2_1:1_55,Kka2,kka2_1:1,P00552,0.743186,NO,55,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.625,-3.678,2.053,,0.517,S,b,0.29,1.19,4.035,,63.64,POH,-2.05967,0.520039,0.00667877,0.743186 kka2_1:4_E182D,kka2_1:4_182,Kka2,kka2_1:4,P00552,0.743258,NO,182,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.516,-2.787,1.271,,0.326,.,B,1.04,0.75,4.755,,65.53,OAA,-1.806,0.168804,0.00641548,0.743258 kka2_1:4_L241D,kka2_1:4_241,Kka2,kka2_1:4,P00552,0.743259,NO,241,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.158,-4.14,2.982,,0.08,H,A,0.55,-0.82,1.598,,63.26,HHH,-1.58533,0.168804,0.0117299,0.743259 kka2_1:8_P194C,kka2_1:8_194,Kka2,kka2_1:8,P00552,0.743286,NO,194,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.846,-5.109,4.263,,0.308,G,A,0.52,-1.19,4.861,,53.03,HOP,-0.888333,0.100394,0.00314194,0.743286 kka2_1:8_P194C,kka2_1:8_194,Kka2,kka2_1:8,P00552,0.743286,NO,194,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.846,-5.109,4.263,,0.308,G,A,0.52,-1.19,4.861,,53.03,HOP,-0.888333,0.100394,0.00314194,0.743286 kka2_1:1_L57P,kka2_1:1_57,Kka2,kka2_1:1,P00552,0.743329,NO,57,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.898,-3.173,1.275,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.520039,0.00723769,0.743329 beta-lactamase_E119R,beta-lactamase_119,TEM-1,beta-lactamase,P62593,0.743346,NO,119,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.412,-3.743,2.331,5.33349,0.358,H,A,1.52,0.51,1.983,,63.99,BAH,-1.623,0.221079,0.00386966,0.743346 beta-lactamase_0_I229L,beta-lactamase_0_229,TEM-1,beta-lactamase_0,P62593,0.743377,NO,229,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.267,-2.225,0.958,,0.083,E,B,0.48,-0.76,1.69,,50,HHH,-1.58767,0.0500837,0.00477249,0.743377 beta-lactamase_2500_K30H,beta-lactamase_2500_30,TEM-1,beta-lactamase_2500,P62593,0.743428,NO,30,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-2.307,-4.558,2.251,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.361275,0.00448593,0.743428 beta-lactamase_2500_I54Q,beta-lactamase_2500_54,TEM-1,beta-lactamase_2500,P62593,0.743567,NO,54,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-2.838,-2.926,0.088,,0.669,E,B,0.48,-0.14,3.946,,73.78,BHH,-2.337,0.361275,0.00403589,0.743567 kka2_1:2_R147H,kka2_1:2_147,Kka2,kka2_1:2,P00552,0.743575,NO,147,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.123,-2.32,1.197,,0.094,H,A,1.2,0.97,0.425,,64.02,PBH,-1.98267,0.295029,0.00549168,0.743575 kka2_1:4_P132K,kka2_1:4_132,Kka2,kka2_1:4,P00552,0.743581,NO,132,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.775,-3.483,2.708,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.168804,0.0018489,0.743581 beta-lactamase_0_L136D,beta-lactamase_0_136,TEM-1,beta-lactamase_0,P62593,0.743582,NO,136,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.232,-4.137,2.905,,,H,A,0.55,-0.34,0.648,,48.95,HHH,-1.088,0.0500837,0.00442304,0.743582 beta-lactamase_L223F,beta-lactamase_223,TEM-1,beta-lactamase,P62593,0.743607,NO,223,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.055,-2.724,1.669,5.42318,0.27,,B,1.3,0.09,1.511,,74.48,HHO,-1.35033,0.221079,0.00372793,0.743607 Pab1_V198G,Pab1_198,Pab1,Pab1,P04147,0.74363,NO,198,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.113,-3.4,2.287,,0.008,E,B,0.61,0.91,,,,HHH,-1.32933,0.175299,0.000268557,0.74363 kka2_1:8_D183Y,kka2_1:8_183,Kka2,kka2_1:8,P00552,0.743717,NO,183,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.204,-4.387,3.183,,0.518,.,b,0.75,0.25,0.347,,52.27,AAH,-1.40533,0.100394,0.00426304,0.743717 kka2_1:8_D183Y,kka2_1:8_183,Kka2,kka2_1:8,P00552,0.743717,NO,183,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.204,-4.387,3.183,,0.518,.,b,0.75,0.25,0.347,,52.27,AAH,-1.40533,0.100394,0.00426304,0.743717 beta-lactamase_0_I206D,beta-lactamase_0_206,TEM-1,beta-lactamase_0,P62593,0.743786,NO,206,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-2.429,-3.794,1.365,,0.173,H,A,0.48,-0.34,3.411,,77.62,HHA,-1.805,0.0500837,0.00528934,0.743786 kka2_1:8_H135T,kka2_1:8_135,Kka2,kka2_1:8,P00552,0.74386,NO,135,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-1.331,-3.65,2.319,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.100394,0.00532566,0.74386 kka2_1:8_H135T,kka2_1:8_135,Kka2,kka2_1:8,P00552,0.74386,NO,135,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-1.331,-3.65,2.319,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.100394,0.00532566,0.74386 beta-lactamase_L247F,beta-lactamase_247,TEM-1,beta-lactamase,P62593,0.744162,NO,247,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.48,-3.834,2.354,5.28771,0.007,E,B,2.89,-0.72,2.951,,63.99,HHO,-1.79833,0.221079,0.00611275,0.744162 kka2_1:8_S204L,kka2_1:8_204,Kka2,kka2_1:8,P00552,0.744261,NO,204,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.353,-3.418,2.065,,0.144,E,A,0.27,-1.2,0.368,,65.53,HPO,-0.953333,0.100394,0.00881794,0.744261 kka2_1:8_S204L,kka2_1:8_204,Kka2,kka2_1:8,P00552,0.744261,NO,204,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.353,-3.418,2.065,,0.144,E,A,0.27,-1.2,0.368,,65.53,HPO,-0.953333,0.100394,0.00881794,0.744261 beta-lactamase_625_T263D,beta-lactamase_625_263,TEM-1,beta-lactamase_625,P62593,0.744346,NO,263,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.213352,0.0110582,0.744346 kka2_1:2_D90N,kka2_1:2_90,Kka2,kka2_1:2,P00552,0.744349,NO,90,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.459,-2.125,-0.334,,0.104,E,B,0.75,0.73,6.085,,64.39,BAH,-1.72833,0.295029,0.00583842,0.744349 kka2_1:8_H135I,kka2_1:8_135,Kka2,kka2_1:8,P00552,0.744401,NO,135,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-1.331,-3.976,2.645,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.100394,0.00532566,0.744401 kka2_1:8_H135I,kka2_1:8_135,Kka2,kka2_1:8,P00552,0.744401,NO,135,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-1.331,-3.976,2.645,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.100394,0.00532566,0.744401 beta-lactamase_E56W,beta-lactamase_56,TEM-1,beta-lactamase,P62593,0.744455,NO,56,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.043,-5.293,3.25,5.65281,0.198,E,B,0.52,0.31,2.022,,72.73,HAP,-1.94033,0.221079,0.00238534,0.744455 beta-lactamase_E35D,beta-lactamase_35,TEM-1,beta-lactamase,P62593,0.744467,NO,35,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-0.869,-2.219,1.35,5.10723,0.15,H,A,0.52,0.21,1.081,,46.85,HAA,-1.88667,0.221079,0.00174441,0.744467 kka2_1:4_G99R,kka2_1:4_99,Kka2,kka2_1:4,P00552,0.744508,NO,99,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.596,-3.961,3.365,,0.368,S,g,0.29,-0.87,,,,OOP,-1.63067,0.168804,0.00186055,0.744508 kka2_1:2_P179T,kka2_1:2_179,Kka2,kka2_1:2,P00552,0.74451,NO,179,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.974,-3.471,2.497,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.295029,0.00298346,0.74451 beta-lactamase_W286F,beta-lactamase_286,TEM-1,beta-lactamase,P62593,0.744511,NO,286,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-1.111,-3.209,2.098,6.64456,0.492,,?,0.01,0.6,,,,BHX,-1.478,0.221079,,0.744511 kka2_1:2_D227H,kka2_1:2_227,Kka2,kka2_1:2,P00552,0.744618,NO,227,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.758,-4.528,2.77,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.295029,0.00745029,0.744618 kka2_1:1_T225C,kka2_1:1_225,Kka2,kka2_1:1,P00552,0.744626,NO,225,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.393,-1.895,-0.498,,0.036,H,A,0.22,-1.22,4.554,,63.64,HPB,-1.58733,0.520039,0.0113598,0.744626 kka2_1:8_G201Y,kka2_1:8_201,Kka2,kka2_1:8,P00552,0.744655,NO,201,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.56,-4.462,2.902,,0.149,T,l,0.75,-0.57,2.152,,52.65,POB,-1.92233,0.100394,0.00820117,0.744655 kka2_1:8_G201Y,kka2_1:8_201,Kka2,kka2_1:8,P00552,0.744655,NO,201,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.56,-4.462,2.902,,0.149,T,l,0.75,-0.57,2.152,,52.65,POB,-1.92233,0.100394,0.00820117,0.744655 kka2_1:2_G164R,kka2_1:2_164,Kka2,kka2_1:2,P00552,0.744683,NO,164,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.869,-3.953,3.084,,0.862,T,l,0.75,1.45,1.539,,64.39,POH,-1.828,0.295029,0.00442091,0.744683 beta-lactamase_2500_I54Y,beta-lactamase_2500_54,TEM-1,beta-lactamase_2500,P62593,0.744778,NO,54,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-2.838,-4.264,1.426,,0.669,E,B,0.48,-0.14,3.946,,73.78,BHH,-2.337,0.361275,0.00403589,0.744778 kka2_1:2_R145Q,kka2_1:2_145,Kka2,kka2_1:2,P00552,0.74479,NO,145,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.804,-2.583,0.779,,0.346,H,A,1.2,1.23,7.961,,63.64,HBP,-1.88033,0.295029,0.00846663,0.74479 kka2_1:2_I196S,kka2_1:2_196,Kka2,kka2_1:2,P00552,0.744801,NO,196,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-2.115,-3.786,1.671,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.295029,0.0107273,0.744801 kka2_1:4_D118N,kka2_1:4_118,Kka2,kka2_1:4,P00552,0.744812,NO,118,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.07,-3.163,1.093,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.168804,0.0067852,0.744812 kka2_1:8_F48V,kka2_1:8_48,Kka2,kka2_1:8,P00552,0.744934,NO,48,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.453,-2.048,0.595,,0.296,E,B,1.62,-0.99,14.194,14.194,55.3,HHH,-1.444,0.100394,0.00475422,0.744934 kka2_1:8_F48V,kka2_1:8_48,Kka2,kka2_1:8,P00552,0.744934,NO,48,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.453,-2.048,0.595,,0.296,E,B,1.62,-0.99,14.194,14.194,55.3,HHH,-1.444,0.100394,0.00475422,0.744934 beta-lactamase_2500_T126L,beta-lactamase_2500_126,TEM-1,beta-lactamase_2500,P62593,0.744988,NO,126,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.122,-3.373,2.251,,0.05,H,A,0.22,-0.05,0.817,,44.41,HPH,-1.60467,0.361275,0.00244552,0.744988 beta-lactamase_2500_L47Q,beta-lactamase_2500_47,TEM-1,beta-lactamase_2500,P62593,0.744994,NO,47,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.876,-3.17,1.294,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.361275,0.00439844,0.744994 kka2_1:8_V186G,kka2_1:8_186,Kka2,kka2_1:8,P00552,0.745005,NO,186,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.011,-3.743,2.732,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.100394,0.00409703,0.745005 kka2_1:8_V186G,kka2_1:8_186,Kka2,kka2_1:8,P00552,0.745005,NO,186,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.011,-3.743,2.732,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.100394,0.00409703,0.745005 kka2_1:2_K138C,kka2_1:2_138,Kka2,kka2_1:2,P00552,0.745044,NO,138,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-2.5,-5.226,2.726,,0.594,H,A,2.34,0.98,21.038,21.038,71.59,HBB,-2.48833,0.295029,0.00628542,0.745044 beta-lactamase_0_W288T,beta-lactamase_0_288,TEM-1,beta-lactamase_0,P62593,0.74522,NO,288,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,,,,,,,,,,,,,BHO,,0.0500837,,0.74522 beta-lactamase_L150G,beta-lactamase_150,TEM-1,beta-lactamase,P62593,0.745384,NO,150,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.326,-3.622,2.296,5.15566,,H,A,1.75,-0.2,1.615,,62.94,HHB,-1.86167,0.221079,0.00463171,0.745384 WW_domain_G185D,WW_domain_185,Yap65,WW_domain,P46937,0.745417,NO,185,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.861,-3.246,2.385,6.22337,,,,,,,,,POP,-1.194,0.153962,0.00199178,0.745417 beta-lactamase_T107I,beta-lactamase_107,TEM-1,beta-lactamase,P62593,0.74543,NO,107,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.117,-3.664,2.547,5.23432,,G,A,2.12,-0.06,3.676,,67.83,HPA,-1.265,0.221079,0.00239347,0.74543 kka2_1:8_R239N,kka2_1:8_239,Kka2,kka2_1:8,P00552,0.745433,NO,239,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.949,-3.912,0.963,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.100394,0.00835326,0.745433 kka2_1:8_R239N,kka2_1:8_239,Kka2,kka2_1:8,P00552,0.745433,NO,239,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.949,-3.912,0.963,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.100394,0.00835326,0.745433 beta-lactamase_156_C121T,beta-lactamase_156_121,TEM-1,beta-lactamase_156,P62593,0.745459,NO,121,C,T,CT,Special,Polar,5.07,5.6,0.53,149,121,119,-2,108.5,116.1,7.6,-0.953,-3.447,2.494,,,H,A,0.46,-0.81,1.136,,63.29,HOP,-1.46767,0.111618,0.000744322,0.745459 kka2_1:1_E149R,kka2_1:1_149,Kka2,kka2_1:1,P00552,0.745486,NO,149,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.994,-2.471,0.477,,0.674,H,A,1.04,1.63,3.671,,71.59,HAH,-1.59667,0.520039,0.00803343,0.745486 beta-lactamase_0_A215K,beta-lactamase_0_215,TEM-1,beta-lactamase_0,P62593,0.745487,NO,215,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.503,-3.575,2.072,,,,a,0.46,-0.93,0.494,,74.48,HHO,-1.42633,0.0500837,0.00544007,0.745487 kka2_1:8_F206I,kka2_1:8_206,Kka2,kka2_1:8,P00552,0.745541,NO,206,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.349,-3.398,2.049,,0.006,E,B,1.62,-1.21,1.052,,63.64,OHH,-1.04,0.100394,0.00936868,0.745541 kka2_1:8_F206I,kka2_1:8_206,Kka2,kka2_1:8,P00552,0.745541,NO,206,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.349,-3.398,2.049,,0.006,E,B,1.62,-1.21,1.052,,63.64,OHH,-1.04,0.100394,0.00936868,0.745541 kka2_1:4_G95V,kka2_1:4_95,Kka2,kka2_1:4,P00552,0.745611,NO,95,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-2.403,-2.997,0.594,,0.126,E,B,0.29,-0.74,0.359,,71.59,HOA,-2.198,0.168804,0.00743616,0.745611 kka2_1:4_R140Q,kka2_1:4_140,Kka2,kka2_1:4,P00552,0.745614,NO,140,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.351,-2.5,1.149,,0.12,H,A,1.2,0.2,2.561,,53.03,BBH,-1.885,0.168804,0.00430167,0.745614 beta-lactamase_0_R59T,beta-lactamase_0_59,TEM-1,beta-lactamase_0,P62593,0.745646,NO,59,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.345,-3.487,2.142,,0.329,S,L,1.2,-0.09,2.919,,73.08,HBO,-2.24267,0.0500837,0.00318082,0.745646 kka2_1:1_P249Q,kka2_1:1_249,Kka2,kka2_1:1,P00552,0.745648,NO,249,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.867,-4.234,2.367,,0.406,.,B,0.52,-0.01,8.037,8.037,92.05,HOA,-1.66867,0.520039,0.011045,0.745648 beta-lactamase_M268C,beta-lactamase_268,TEM-1,beta-lactamase,P62593,0.745706,NO,268,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-2.023,-4.876,2.853,5.4797,0.471,H,A,0.09,0.3,1.071,,65.73,PHA,-2.16233,0.221079,0.0102525,0.745706 kka2_1:4_N195K,kka2_1:4_195,Kka2,kka2_1:4,P00552,0.745732,NO,195,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-0.836,-3.304,2.468,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.168804,0.00276134,0.745732 beta-lactamase_2500_V214S,beta-lactamase_2500_214,TEM-1,beta-lactamase_2500,P62593,0.745778,NO,214,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.299,-3.408,2.109,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.361275,0.00628442,0.745778 kka2_1:4_G210P,kka2_1:4_210,Kka2,kka2_1:4,P00552,0.745778,NO,210,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.095,-3.953,2.858,,0.103,T,A,0.29,-0.62,0.271,,50,OOB,-0.966667,0.168804,0.00598378,0.745778 gb1_L231I,gb1_231,gb1,gb1,P06654,0.74578,NO,231,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.603,-2.978,1.375,,,,,,,0.219,,11.83,BHH,-1.82633,0.177985,0.00322797,0.74578 gb1_Y271C,gb1_271,gb1,gb1,P06654,0.74578,NO,271,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-1.181,-4.639,3.458,,,,,,,,,,PHA,-1.92933,0.177985,0.00236544,0.74578 beta-lactamase_0_Y262A,beta-lactamase_0_262,TEM-1,beta-lactamase_0,P62593,0.745804,NO,262,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.0500837,0.00853516,0.745804 kka2_1:2_Q252Y,kka2_1:2_252,Kka2,kka2_1:2,P00552,0.74584,NO,252,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.63,-4.393,1.763,,0.906,H,A,0.64,0.35,5.613,,92.05,PPB,-2.20733,0.295029,0.0121001,0.74584 beta-lactamase_0_T186F,beta-lactamase_0_186,TEM-1,beta-lactamase_0,P62593,0.745885,NO,186,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.522,-4.342,1.82,,0.396,H,A,0.22,-0.28,16.606,16.606,77.62,HPP,-1.77633,0.0500837,0.00485034,0.745885 beta-lactamase_2500_R202M,beta-lactamase_2500_202,TEM-1,beta-lactamase_2500,P62593,0.745924,NO,202,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.292,-4.499,3.207,,0.188,H,A,1.2,0.62,3.734,,77.62,PBP,-1.54767,0.361275,0.00321899,0.745924 kka2_1:1_G181T,kka2_1:1_181,Kka2,kka2_1:1,P00552,0.746068,NO,181,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-2.698,-2.358,-0.34,,0.379,S,B,0.75,0.78,15.356,15.356,71.59,AOA,-2.21,0.520039,0.00728319,0.746068 beta-lactamase_S201Y,beta-lactamase_201,TEM-1,beta-lactamase,P62593,0.746096,NO,201,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.183,-4.222,3.039,4.85496,0.064,H,A,0.77,-0.07,4.045,,64.69,HPB,-1.451,0.221079,0.00198815,0.746096 beta-lactamase_0_L192C,beta-lactamase_0_192,TEM-1,beta-lactamase_0,P62593,0.74613,NO,192,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.254,-4.743,3.489,,0.095,H,A,0.55,0.35,1.756,,60.14,HHP,-1.41833,0.0500837,0.00558728,0.74613 beta-lactamase_0_Q204D,beta-lactamase_0_204,TEM-1,beta-lactamase_0,P62593,0.746136,NO,204,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-1.382,-3.553,2.171,,0.204,H,A,0.64,0.09,2.646,,66.08,PPH,-1.49067,0.0500837,0.00364106,0.746136 WW_domain_P174Q,WW_domain_174,Yap65,WW_domain,P46937,0.746189,NO,174,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.035,-3.676,2.641,,,,,,,,,,HOH,-1.261,0.153962,0.000711366,0.746189 beta-lactamase_P165F,beta-lactamase_165,TEM-1,beta-lactamase,P62593,0.746211,NO,165,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.373,-4.322,2.949,5.33889,0.203,T,A,0.99,-0.31,0.414,,73.78,AOA,-1.359,0.221079,0.00549538,0.746211 kka2_1:1_S32R,kka2_1:1_32,Kka2,kka2_1:1,P00552,0.746282,NO,32,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-0.804,-3.736,2.932,,0.768,S,b,0.27,3.75,,,,OPA,-1.74533,0.520039,0.00149998,0.746282 beta-lactamase_2500_I258M,beta-lactamase_2500_258,TEM-1,beta-lactamase_2500,P62593,0.746293,NO,258,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.361275,0.007931,0.746293 kka2_1:2_F48S,kka2_1:2_48,Kka2,kka2_1:2,P00552,0.746326,NO,48,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.453,-3.787,2.334,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.295029,0.00475422,0.746326 Pab1_I157K,Pab1_157,Pab1,Pab1,P04147,0.746357,NO,157,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.623,-3.664,2.041,,,,,,,1.439,,79.72,BHH,-1.28667,0.175299,0.0018103,0.746357 kka2_1:8_M116K,kka2_1:8_116,Kka2,kka2_1:8,P00552,0.746431,NO,116,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-2.482,-3.871,1.389,,,H,A,1.59,-0.88,4.659,,71.59,HHH,-1.63867,0.100394,0.00745147,0.746431 kka2_1:8_M116K,kka2_1:8_116,Kka2,kka2_1:8,P00552,0.746431,NO,116,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-2.482,-3.871,1.389,,,H,A,1.59,-0.88,4.659,,71.59,HHH,-1.63867,0.100394,0.00745147,0.746431 kka2_1:4_Q27K,kka2_1:4_27,Kka2,kka2_1:4,P00552,0.746469,NO,27,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-1.659,-3.492,1.833,,0.608,,A,0.4,0.71,1.498,,65.53,PPP,-1.90733,0.168804,0.00595365,0.746469 kka2_1:2_D250Y,kka2_1:2_250,Kka2,kka2_1:2,P00552,0.746497,NO,250,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.015,-4.409,3.394,,0.274,.,b,0.75,-0.46,3.796,,51.89,OAP,-1.83933,0.295029,0.0177103,0.746497 beta-lactamase_156_R162Y,beta-lactamase_156_162,TEM-1,beta-lactamase_156,P62593,0.746501,NO,162,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.016,-4.207,3.191,,0.124,S,B,1.2,-0.37,7.444,,64.69,ABH,-1.25,0.111618,0.000561334,0.746501 beta-lactamase_0_A183E,beta-lactamase_0_183,TEM-1,beta-lactamase_0,P62593,0.746514,NO,183,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.231,-3.42,2.189,,0.155,H,A,0.46,-0.91,1.48,,77.62,HHH,-1.53367,0.0500837,0.00296631,0.746514 beta-lactamase_2500_V72A,beta-lactamase_2500_72,TEM-1,beta-lactamase_2500,P62593,0.74654,NO,72,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.658,-1.729,0.071,,,H,A,0.44,-1.03,2.079,,65.73,BHH,-1.32167,0.361275,0.00501194,0.74654 gb1_E282C,gb1_282,gb1,gb1,P06654,0.746559,NO,282,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.318,-4.909,3.591,,,,,,,1.075,,35.71,PAO,-1.573,0.177985,0.00209643,0.746559 gb1_E282F,gb1_282,gb1,gb1,P06654,0.746559,NO,282,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.318,-4.062,2.744,,,,,,,1.075,,35.71,PAO,-1.573,0.177985,0.00209643,0.746559 gb1_G235H,gb1_235,gb1,gb1,P06654,0.746559,NO,235,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.419,-4.491,3.072,,,,,,,0.476,,11.83,POB,-1.86433,0.177985,0.00297491,0.746559 gb1_G240H,gb1_240,gb1,gb1,P06654,0.746559,NO,240,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.921,-4.416,3.495,,,,,,,,,,BOA,-1.87867,0.177985,0.00270792,0.746559 gb1_G240S,gb1_240,gb1,gb1,P06654,0.746559,NO,240,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.921,-2.896,1.975,,,,,,,,,,BOA,-1.87867,0.177985,0.00270792,0.746559 gb1_G264I,gb1_264,gb1,gb1,P06654,0.746559,NO,264,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.833,-2.44,0.607,,,,,,,0.864,,44.87,POH,-1.61267,0.177985,0.0049716,0.746559 gb1_L233N,gb1_233,gb1,gb1,P06654,0.746559,NO,233,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-2.678,-3.68,1.002,,,,,,,0.822,,45.54,HHP,-2.30267,0.177985,0.00266958,0.746559 beta-lactamase_0_H287Y,beta-lactamase_0_287,TEM-1,beta-lactamase_0,P62593,0.746598,NO,287,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,,,,,,,,,,,,,BBH,-1.111,0.0500837,,0.746598 kka2_1:1_I196Q,kka2_1:1_196,Kka2,kka2_1:1,P00552,0.746606,NO,196,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-2.115,-4.384,2.269,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.520039,0.0107273,0.746606 beta-lactamase_I283K,beta-lactamase_283,TEM-1,beta-lactamase,P62593,0.746614,NO,283,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.638,-3.801,2.163,5.4178,0.165,H,A,1.23,0.04,1.576,,69.23,HHB,-1.735,0.221079,0.0429138,0.746614 kka2_1:8_R217V,kka2_1:8_217,Kka2,kka2_1:8,P00552,0.746669,NO,217,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.158,-3.458,2.3,,0.252,T,A,0.16,-0.59,1.151,,52.27,ABH,-1.127,0.100394,0.0047191,0.746669 kka2_1:8_R217V,kka2_1:8_217,Kka2,kka2_1:8,P00552,0.746669,NO,217,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.158,-3.458,2.3,,0.252,T,A,0.16,-0.59,1.151,,52.27,ABH,-1.127,0.100394,0.0047191,0.746669 beta-lactamase_2500_R176A,beta-lactamase_2500_176,TEM-1,beta-lactamase_2500,P62593,0.746671,NO,176,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-0.863,-3.078,2.215,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.361275,0.00105554,0.746671 beta-lactamase_0_P65T,beta-lactamase_0_65,TEM-1,beta-lactamase_0,P62593,0.746725,NO,65,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.894,-3.44,2.546,,0.098,E,B,0.52,-0.62,0.663,,40.56,HOH,-1.03233,0.0500837,0.00152776,0.746725 beta-lactamase_0_A222Q,beta-lactamase_0_222,TEM-1,beta-lactamase_0,P62593,0.746848,NO,222,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.103,-4.105,2.002,,0.233,H,A,0.46,-0.25,2.015,,77.62,PHH,-1.63733,0.0500837,0.00466094,0.746848 kka2_1:8_T225K,kka2_1:8_225,Kka2,kka2_1:8,P00552,0.747035,NO,225,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.393,-3.78,1.387,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.100394,0.0113598,0.747035 kka2_1:8_T225K,kka2_1:8_225,Kka2,kka2_1:8,P00552,0.747035,NO,225,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.393,-3.78,1.387,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.100394,0.0113598,0.747035 beta-lactamase_P65S,beta-lactamase_65,TEM-1,beta-lactamase,P62593,0.74704,NO,65,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.894,-3.44,2.546,5.59094,0.098,E,B,0.23,-0.62,0.623,,40.56,HOH,-1.03233,0.221079,0.00152776,0.74704 beta-lactamase_0_I277N,beta-lactamase_0_277,TEM-1,beta-lactamase_0,P62593,0.74711,NO,277,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.0500837,0.0169305,0.74711 kka2_1:4_S32V,kka2_1:4_32,Kka2,kka2_1:4,P00552,0.747151,NO,32,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-0.804,-3.557,2.753,,0.768,S,b,0.27,3.75,,,,OPA,-1.74533,0.168804,0.00149998,0.747151 beta-lactamase_G52Y,beta-lactamase_52,TEM-1,beta-lactamase,P62593,0.747177,NO,52,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.149,-4.436,3.287,5.12093,0.299,,l,0.77,-0.04,2.103,,64.69,POB,-1.66267,0.221079,0.00340138,0.747177 beta-lactamase_2500_T187C,beta-lactamase_2500_187,TEM-1,beta-lactamase_2500,P62593,0.747185,NO,187,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.401,-4.859,3.458,,0.007,H,A,0.22,-1.19,3.91,,67.48,PPH,-1.69633,0.361275,0.00491782,0.747185 Pab1_G188W,Pab1_188,Pab1,Pab1,P04147,0.747252,NO,188,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.809,-4.915,4.106,,0.379,E,g,,2.18,,,,POH,-1.14633,0.175299,0.000280911,0.747252 beta-lactamase_0_R176A,beta-lactamase_0_176,TEM-1,beta-lactamase_0,P62593,0.7473,NO,176,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-0.863,-3.078,2.215,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.0500837,0.00105554,0.7473 gb1_Q258Y,gb1_258,gb1,gb1,P06654,0.747334,NO,258,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.095,-4.037,1.942,,,,,,,0.86,,37.28,BPH,-1.88333,0.177985,0.00437595,0.747334 kka2_1:8_G88V,kka2_1:8_88,Kka2,kka2_1:8,P00552,0.74739,NO,88,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.689,-2.928,1.239,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.100394,0.00685559,0.74739 kka2_1:8_G88V,kka2_1:8_88,Kka2,kka2_1:8,P00552,0.74739,NO,88,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.689,-2.928,1.239,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.100394,0.00685559,0.74739 kka2_1:4_I228R,kka2_1:4_228,Kka2,kka2_1:4,P00552,0.747441,NO,228,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.142,-4.209,3.067,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.168804,0.00458834,0.747441 PSD95pdz3_E373F,PSD95pdz3_373,PSD95pdz3,PSD95pdz3,P31016,0.747524,NO,373,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.404,-3.974,2.57,5.79743,,,,,27.9833,,,,BAP,-1.57667,0.0758425,0.000387698,0.747524 kka2_1:8_L94P,kka2_1:8_94,Kka2,kka2_1:8,P00552,0.747532,NO,94,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.618,-4.098,2.48,,0.058,E,B,1.59,-0.52,2.197,,56.06,HHO,-1.612,0.100394,0.00520888,0.747532 kka2_1:8_L94P,kka2_1:8_94,Kka2,kka2_1:8,P00552,0.747532,NO,94,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.618,-4.098,2.48,,0.058,E,B,1.59,-0.52,2.197,,56.06,HHO,-1.612,0.100394,0.00520888,0.747532 beta-lactamase_0_T186N,beta-lactamase_0_186,TEM-1,beta-lactamase_0,P62593,0.747579,NO,186,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.522,-3.756,1.234,,0.396,H,A,0.22,-0.28,16.606,16.606,77.62,HPP,-1.77633,0.0500837,0.00485034,0.747579 beta-lactamase_2500_S256F,beta-lactamase_2500_256,TEM-1,beta-lactamase_2500,P62593,0.747601,NO,256,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.361275,0.00710634,0.747601 beta-lactamase_0_D83S,beta-lactamase_0_83,TEM-1,beta-lactamase_0,P62593,0.747624,NO,83,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.066,-2.542,1.476,,0.354,H,A,0.75,0.22,0.617,,48.95,HAH,-1.34733,0.0500837,0.00205968,0.747624 kka2_1:1_V83G,kka2_1:1_83,Kka2,kka2_1:1,P00552,0.74764,NO,83,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-2.567,-3.646,1.079,,0.358,E,B,0.44,0.53,5.931,,71.59,AHH,-2.264,0.520039,0.00650486,0.74764 kka2_1:2_L70M,kka2_1:2_70,Kka2,kka2_1:2,P00552,0.747663,NO,70,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.017,-2.172,1.155,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.295029,0.00411884,0.747663 beta-lactamase_0_L120K,beta-lactamase_0_120,TEM-1,beta-lactamase_0,P62593,0.747664,NO,120,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.044,-3.668,2.624,,,H,A,0.55,-1.13,1.2,,64.69,AHO,-1.13633,0.0500837,0.00143563,0.747664 kka2_1:4_R147T,kka2_1:4_147,Kka2,kka2_1:4,P00552,0.7477,NO,147,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.123,-3.56,2.437,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.168804,0.00549168,0.7477 kka2_1:1_F20L,kka2_1:1_20,Kka2,kka2_1:1,P00552,0.747764,NO,20,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-3.354,-3.523,0.169,,0.935,T,B,0.58,-0.41,1.657,,92.05,HHO,-1.992,0.520039,0.00701744,0.747764 beta-lactamase_S2E,beta-lactamase_2,TEM-1,beta-lactamase,P62593,0.747769,NO,2,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.942,-3.37,1.428,,,,,,,2.36,,65.38,HPH,-2.02767,0.221079,0.00227352,0.747769 kka2_1:1_A215S,kka2_1:1_215,Kka2,kka2_1:1,P00552,0.747792,NO,215,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.968,-1.873,0.905,,0.039,E,B,0.46,-0.59,0.754,,50.38,HHA,-1.00467,0.520039,0.00529129,0.747792 kka2_1:1_G10T,kka2_1:1_10,Kka2,kka2_1:1,P00552,0.747809,NO,10,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.921,-3.48,1.559,,,,,,,1.862,,71.59,HOP,-2.10733,0.520039,0.00289233,0.747809 beta-lactamase_2500_G265M,beta-lactamase_2500_265,TEM-1,beta-lactamase_2500,P62593,0.747828,NO,265,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.361275,0.00811926,0.747828 beta-lactamase_0_E46G,beta-lactamase_0_46,TEM-1,beta-lactamase_0,P62593,0.747899,NO,46,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.94,-2.778,0.838,,0.021,E,B,1.04,0.14,30.306,30.306,59.44,HAH,-2.079,0.0500837,0.00427568,0.747899 kka2_1:2_D183N,kka2_1:2_183,Kka2,kka2_1:2,P00552,0.747919,NO,183,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.204,-2.35,1.146,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.295029,0.00426304,0.747919 beta-lactamase_I275Y,beta-lactamase_275,TEM-1,beta-lactamase,P62593,0.747961,NO,275,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.397,-3.906,2.509,5.3999,0.015,H,A,1,-0.52,0.836,,62.59,PHH,-1.541,0.221079,0.0141984,0.747961 kka2_1:4_V75Y,kka2_1:4_75,Kka2,kka2_1:4,P00552,0.747966,NO,75,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-2.06,-4.054,1.994,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.168804,0.00693733,0.747966 beta-lactamase_625_T131Y,beta-lactamase_625_131,TEM-1,beta-lactamase_625,P62593,0.747987,NO,131,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.328,-4.285,2.957,,,H,A,0.22,-0.69,2.031,,67.48,PPH,-1.00867,0.213352,0.00345886,0.747987 beta-lactamase_39_C75D,beta-lactamase_39_75,TEM-1,beta-lactamase_39,P62593,0.748003,NO,75,C,D,CD,Special,negativeCharge,5.07,5.0516,-0.0184,154,121,133,12,108.5,111.1,2.6,-1.245,-3.832,2.587,,,H,A,0.46,-0.87,2.369,,50,HOO,-1.24333,0.0495842,0.0034616,0.748003 kka2_1:8_L241P,kka2_1:8_241,Kka2,kka2_1:8,P00552,0.748063,NO,241,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.158,-4.275,3.117,,0.08,H,A,1.59,-0.82,1.136,,63.26,HHH,-1.58533,0.100394,0.0117299,0.748063 kka2_1:8_L241P,kka2_1:8_241,Kka2,kka2_1:8,P00552,0.748063,NO,241,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.158,-4.275,3.117,,0.08,H,A,1.59,-0.82,1.136,,63.26,HHH,-1.58533,0.100394,0.0117299,0.748063 gb1_N263K,gb1_263,gb1,gb1,P06654,0.748106,NO,263,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-1.162,-3.009,1.847,,,,,,,,,,APO,-2.04233,0.177985,0.0035297,0.748106 gb1_V265C,gb1_265,gb1,gb1,P06654,0.748106,NO,265,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.843,-4.578,2.735,,,,,,,0.402,,11.83,OHA,-1.64567,0.177985,0.00360613,0.748106 beta-lactamase_625_D212C,beta-lactamase_625_212,TEM-1,beta-lactamase_625,P62593,0.748295,NO,212,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.624,-5.061,3.437,,0.037,,b,0.75,-0.58,1.516,,74.48,HAB,-1.77667,0.213352,0.00644302,0.748295 beta-lactamase_0_G234H,beta-lactamase_0_234,TEM-1,beta-lactamase_0,P62593,0.748302,NO,234,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.62,-4.68,4.06,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.0500837,0.000889577,0.748302 kka2_1:2_P98V,kka2_1:2_98,Kka2,kka2_1:2,P00552,0.748347,NO,98,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.526,-3.691,2.165,,0.391,S,B,0.52,-0.65,2.82,,63.26,HOO,-1.19167,0.295029,0.00622754,0.748347 kka2_1:2_Q219H,kka2_1:2_219,Kka2,kka2_1:2,P00552,0.748383,NO,219,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-0.93,-4.282,3.352,,0.088,H,A,0.4,-0.85,1.917,,50,HPA,-1.05167,0.295029,0.00237913,0.748383 kka2_1:8_R217S,kka2_1:8_217,Kka2,kka2_1:8,P00552,0.748417,NO,217,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.158,-3.548,2.39,,0.252,T,A,0.16,-0.59,1.151,,52.27,ABH,-1.127,0.100394,0.0047191,0.748417 kka2_1:8_R217S,kka2_1:8_217,Kka2,kka2_1:8,P00552,0.748417,NO,217,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.158,-3.548,2.39,,0.252,T,A,0.16,-0.59,1.151,,52.27,ABH,-1.127,0.100394,0.0047191,0.748417 beta-lactamase_0_S201N,beta-lactamase_0_201,TEM-1,beta-lactamase_0,P62593,0.748438,NO,201,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.183,-3.471,2.288,,0.064,H,A,0.27,-0.07,3.54,,64.69,HPB,-1.451,0.0500837,0.00198815,0.748438 beta-lactamase_625_T27K,beta-lactamase_625_27,TEM-1,beta-lactamase_625,P62593,0.748451,NO,27,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.905,-3.516,1.611,,0.007,H,A,0.22,-0.37,3.72,,93.01,APH,-1.97933,0.213352,0.00306559,0.748451 kka2_1:8_L223R,kka2_1:8_223,Kka2,kka2_1:8,P00552,0.748523,NO,223,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.861,-4.044,3.183,,,H,A,1.59,-1.24,1.017,,50,HHH,-0.854333,0.100394,0.00253574,0.748523 kka2_1:8_L223R,kka2_1:8_223,Kka2,kka2_1:8,P00552,0.748523,NO,223,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.861,-4.044,3.183,,,H,A,1.59,-1.24,1.017,,50,HHH,-0.854333,0.100394,0.00253574,0.748523 kka2_1:2_R44W,kka2_1:2_44,Kka2,kka2_1:2,P00552,0.748636,NO,44,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.062,-5.515,3.453,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.295029,0.00745043,0.748636 PSD95pdz3_I316R,PSD95pdz3_316,PSD95pdz3,PSD95pdz3,P31016,0.748665,NO,316,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.63,-3.84,2.21,5.46166,,,,,19.005,,,,HHB,-1.62733,0.0758425,0.00112762,0.748665 beta-lactamase_L73Q,beta-lactamase_73,TEM-1,beta-lactamase,P62593,0.748715,NO,73,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.507,-4.261,2.754,5.84139,,H,A,1.75,-0.64,2.09,,67.83,HHH,-1.487,0.221079,0.00488983,0.748715 beta-lactamase_0_T69F,beta-lactamase_0_69,TEM-1,beta-lactamase_0,P62593,0.748717,NO,69,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-0.973,-4.127,3.154,,,G,A,0.22,-1.24,0.505,,93.01,PPH,-1.01833,0.0500837,0.00127498,0.748717 PSD95pdz3_I316Y,PSD95pdz3_316,PSD95pdz3,PSD95pdz3,P31016,0.74874,NO,316,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.63,-3.619,1.989,5.46166,,,,,19.005,,,,HHB,-1.62733,0.0758425,0.00112762,0.74874 kka2_1:8_G99V,kka2_1:8_99,Kka2,kka2_1:8,P00552,0.748805,NO,99,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.596,-3.782,3.186,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.100394,0.00186055,0.748805 kka2_1:8_G99V,kka2_1:8_99,Kka2,kka2_1:8,P00552,0.748805,NO,99,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.596,-3.782,3.186,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.100394,0.00186055,0.748805 beta-lactamase_0_R202N,beta-lactamase_0_202,TEM-1,beta-lactamase_0,P62593,0.74882,NO,202,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.292,-3.543,2.251,,0.188,H,A,1.2,0.62,7.016,,77.62,PBP,-1.54767,0.0500837,0.00321899,0.74882 gb1_A260T,gb1_260,gb1,gb1,P06654,0.748874,NO,260,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.486,-3.114,1.628,,,,,,,0.173,,9.6,HHP,-1.70967,0.177985,0.0055808,0.748874 gb1_N263M,gb1_263,gb1,gb1,P06654,0.748874,NO,263,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-1.162,-4.482,3.32,,,,,,,,,,APO,-2.04233,0.177985,0.0035297,0.748874 beta-lactamase_0_A40N,beta-lactamase_0_40,TEM-1,beta-lactamase_0,P62593,0.74889,NO,40,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.402,-3.756,2.354,,0.155,S,B,0.46,0.21,0.783,,73.78,OHB,-1.40267,0.0500837,0.00490026,0.74889 kka2_1:1_W91R,kka2_1:1_91,Kka2,kka2_1:1,P00552,0.748908,NO,91,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-1.178,-2.437,1.259,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.520039,0.00358653,0.748908 beta-lactamase_0_R59M,beta-lactamase_0_59,TEM-1,beta-lactamase_0,P62593,0.74891,NO,59,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.345,-4.605,3.26,,0.329,S,L,1.2,-0.09,2.919,,73.08,HBO,-2.24267,0.0500837,0.00318082,0.74891 kka2_1:1_S54G,kka2_1:1_54,Kka2,kka2_1:1,P00552,0.748952,NO,54,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.471,-2.892,0.421,,0.408,S,b,0.27,1.01,6.085,,71.59,HPO,-2.259,0.520039,0.00782867,0.748952 PSD95pdz3_G351I,PSD95pdz3_351,PSD95pdz3,PSD95pdz3,P31016,0.748964,NO,351,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.008,-3.917,2.909,5.44798,,,,,20.7625,,,,POA,-1.37133,0.0758425,0.000691282,0.748964 beta-lactamase_625_Y95H,beta-lactamase_625_95,TEM-1,beta-lactamase_625,P62593,0.749084,NO,95,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-1.715,-3.182,1.467,,0.122,,b,0.21,-0.37,3.355,,77.62,BHP,-2.16167,0.213352,0.00479449,0.749084 kka2_1:8_H162Q,kka2_1:8_162,Kka2,kka2_1:8,P00552,0.749158,NO,162,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-2.319,-3.703,1.384,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.100394,0.00616145,0.749158 kka2_1:8_H162Q,kka2_1:8_162,Kka2,kka2_1:8,P00552,0.749158,NO,162,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-2.319,-3.703,1.384,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.100394,0.00616145,0.749158 beta-lactamase_P224A,beta-lactamase_224,TEM-1,beta-lactamase,P62593,0.749251,NO,224,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.893,-3.071,2.178,5.179,0.383,,B,0.99,-0.3,0.383,,74.48,HOH,-1.26433,0.221079,0.00189564,0.749251 beta-lactamase_A23D,beta-lactamase_23,TEM-1,beta-lactamase,P62593,0.749398,NO,23,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.548,-3.654,2.106,,,,,,,0.801,,93.01,HHB,-2.235,0.221079,0.00245563,0.749398 kka2_1:2_E235A,kka2_1:2_235,Kka2,kka2_1:2,P00552,0.749479,NO,235,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.955,-1.909,-0.046,,0.631,H,A,1.04,0.12,26.048,26.048,65.53,OAH,-2.07267,0.295029,0.0102806,0.749479 kka2_1:2_A110R,kka2_1:2_110,Kka2,kka2_1:2,P00552,0.749503,NO,110,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.064,-3.093,1.029,,0.175,H,A,0.46,-1.19,23.237,23.237,71.59,OHA,-1.91867,0.295029,0.00759851,0.749503 gb1_F278L,gb1_278,gb1,gb1,P06654,0.749639,NO,278,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.418,-2.899,1.481,,,,,,,3.233,,35.71,PHP,-1.503,0.177985,0.00295699,0.749639 beta-lactamase_2500_W227F,beta-lactamase_2500_227,TEM-1,beta-lactamase_2500,P62593,0.74964,NO,227,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-0.982,-2.609,1.627,,0.272,,B,0.47,-0.29,1.37,,74.48,OHH,-1.595,0.361275,0.00226019,0.74964 beta-lactamase_0_L89F,beta-lactamase_0_89,TEM-1,beta-lactamase_0,P62593,0.749646,NO,89,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.096,-3.844,2.748,,0.168,T,A,0.55,0.63,2.373,,64.34,PHO,-1.75767,0.0500837,0.00207068,0.749646 kka2_1:8_E59P,kka2_1:8_59,Kka2,kka2_1:8,P00552,0.749651,NO,59,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-0.952,-3.748,2.796,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.100394,0.00280355,0.749651 kka2_1:8_E59P,kka2_1:8_59,Kka2,kka2_1:8,P00552,0.749651,NO,59,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-0.952,-3.748,2.796,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.100394,0.00280355,0.749651 kka2_1:1_S251P,kka2_1:1_251,Kka2,kka2_1:1,P00552,0.749659,NO,251,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.636,-2.034,-0.602,,0.712,H,A,0.27,-0.25,1.356,,71.59,APP,-2.09367,0.520039,0.0138916,0.749659 beta-lactamase_V214Y,beta-lactamase_214,TEM-1,beta-lactamase,P62593,0.749699,NO,214,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.299,-4.125,2.826,5.74008,0.375,S,A,1.19,-0.44,1.899,,74.48,BHH,-1.53733,0.221079,0.00628442,0.749699 kka2_1:8_L170P,kka2_1:8_170,Kka2,kka2_1:8,P00552,0.749722,NO,170,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.28,-4.106,2.826,,0.029,H,A,1.59,0.11,1.453,,62.5,AHH,-1.534,0.100394,0.00730791,0.749722 kka2_1:8_L170P,kka2_1:8_170,Kka2,kka2_1:8,P00552,0.749722,NO,170,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.28,-4.106,2.826,,0.029,H,A,1.59,0.11,1.453,,62.5,AHH,-1.534,0.100394,0.00730791,0.749722 kka2_1:4_H162D,kka2_1:4_162,Kka2,kka2_1:4,P00552,0.749819,NO,162,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-2.319,-3.685,1.366,,0.071,G,A,0.17,1.01,3.187,,64.39,ABP,-2.02067,0.168804,0.00616145,0.749819 kka2_1:1_P167T,kka2_1:1_167,Kka2,kka2_1:1,P00552,0.749838,NO,167,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-2.403,-2.47,0.067,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.520039,0.00543203,0.749838 kka2_1:8_R226L,kka2_1:8_226,Kka2,kka2_1:8,P00552,0.749863,NO,226,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.392,-3.592,2.2,,0.222,H,A,0.16,-0.71,3.818,,56.06,PBA,-1.84767,0.100394,0.0108032,0.749863 kka2_1:8_R226L,kka2_1:8_226,Kka2,kka2_1:8,P00552,0.749863,NO,226,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.392,-3.592,2.2,,0.222,H,A,0.16,-0.71,3.818,,56.06,PBA,-1.84767,0.100394,0.0108032,0.749863 beta-lactamase_T107G,beta-lactamase_107,TEM-1,beta-lactamase,P62593,0.749941,NO,107,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.117,-3.227,2.11,5.23432,,G,A,2.12,-0.06,3.676,,67.83,HPA,-1.265,0.221079,0.00239347,0.749941 kka2_1:4_R202I,kka2_1:4_202,Kka2,kka2_1:4,P00552,0.749991,NO,202,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.761,-3.279,1.518,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.168804,0.00696498,0.749991 Ubiquitin_H68V,Ubiquitin_68,Uba1,Ubiquitin,P0CG48,0.75,NO,68,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-1.869,-3.544,1.675,4.81902,0.194,E,B,0.72,-1.02,21.325,21.325,65.11,HBH,-1.583,0.205827,0.000925438,0.75 Ubiquitin_L43Y,Ubiquitin_43,Uba1,Ubiquitin,P0CG48,0.75,NO,43,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.269,-4.063,2.794,4.8799,,E,B,1.75,-1.17,10.246,10.246,53.87,BHH,-1.46867,0.205827,0.000572481,0.75 Ubiquitin_Q40D,Ubiquitin_40,Uba1,Ubiquitin,P0CG48,0.75,NO,40,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-1.752,-2.752,1,4.7807,0.387,G,A,,0.03,,,,APP,-1.62433,0.205827,0.000619089,0.75 kka2_1:4_D134R,kka2_1:4_134,Kka2,kka2_1:4,P00552,0.75002,NO,134,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.969,-3.942,2.973,,0.421,B,B,0.75,0.31,0.733,,49.62,HAB,-1.057,0.168804,0.00270812,0.75002 kka2_1:4_R121G,kka2_1:4_121,Kka2,kka2_1:4,P00552,0.750024,NO,121,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.552,-3.527,1.975,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.168804,0.00523326,0.750024 beta-lactamase_0_L74D,beta-lactamase_0_74,TEM-1,beta-lactamase_0,P62593,0.750055,NO,74,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.296,-4.023,2.727,,,H,A,0.55,-0.91,1.46,,50,HHO,-1.34933,0.0500837,0.00493255,0.750055 beta-lactamase_0_T187C,beta-lactamase_0_187,TEM-1,beta-lactamase_0,P62593,0.750193,NO,187,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.401,-4.859,3.458,,0.007,H,A,0.22,-1.19,3.259,,67.48,PPH,-1.69633,0.0500837,0.00491782,0.750193 beta-lactamase_0_A235N,beta-lactamase_0_235,TEM-1,beta-lactamase_0,P62593,0.750218,NO,235,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.266,-3.746,2.48,,0.32,E,B,0.46,-0.86,2.261,,50,OHO,-0.89,0.0500837,0.00493474,0.750218 kka2_1:1_E161R,kka2_1:1_161,Kka2,kka2_1:1,P00552,0.750329,NO,161,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.581,-3.888,2.307,,0.829,G,A,1.04,2.24,1.612,,92.05,AAB,-1.861,0.520039,0.00760103,0.750329 kka2_1:8_F171C,kka2_1:8_171,Kka2,kka2_1:8,P00552,0.750331,NO,171,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.326,-4.966,3.64,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.100394,0.00821426,0.750331 kka2_1:8_F171C,kka2_1:8_171,Kka2,kka2_1:8,P00552,0.750331,NO,171,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.326,-4.966,3.64,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.100394,0.00821426,0.750331 kka2_1:8_Y257T,kka2_1:8_257,Kka2,kka2_1:8,P00552,0.750331,NO,257,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-1.064,-3.734,2.67,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.100394,0.0148191,0.750331 kka2_1:8_Y257T,kka2_1:8_257,Kka2,kka2_1:8,P00552,0.750331,NO,257,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-1.064,-3.734,2.67,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.100394,0.0148191,0.750331 beta-lactamase_2500_G216H,beta-lactamase_2500_216,TEM-1,beta-lactamase_2500,P62593,0.750352,NO,216,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.477,-4.598,3.121,,0.437,I,A,0.29,-0.58,1.983,,74.48,HOO,-1.68067,0.361275,0.00639568,0.750352 beta-lactamase_0_D161G,beta-lactamase_0_161,TEM-1,beta-lactamase_0,P62593,0.750353,NO,161,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.891,-3.177,2.286,,0.341,,A,0.75,-0.52,0.795,,61.19,HAB,-0.961333,0.0500837,0.000897697,0.750353 gb1_E282N,gb1_282,gb1,gb1,P06654,0.7504,NO,282,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.318,-3.218,1.9,,,,,,,1.075,,35.71,PAO,-1.573,0.177985,0.00209643,0.7504 gb1_G240I,gb1_240,gb1,gb1,P06654,0.7504,NO,240,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.921,-3.971,3.05,,,,,,,,,,BOA,-1.87867,0.177985,0.00270792,0.7504 gb1_L238Q,gb1_238,gb1,gb1,P06654,0.7504,NO,238,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-2.98,-2.267,-0.713,,,,,,,0.504,,45.54,PHB,-2.58633,0.177985,0.00205885,0.7504 beta-lactamase_0_G52F,beta-lactamase_0_52,TEM-1,beta-lactamase_0,P62593,0.750442,NO,52,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.149,-4.393,3.244,,0.299,,l,0.29,-0.04,1.164,,64.69,POB,-1.66267,0.0500837,0.00340138,0.750442 kka2_1:1_L152R,kka2_1:1_152,Kka2,kka2_1:1,P00552,0.750559,NO,152,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.521,-2.523,1.002,,0.547,.,A,0.55,1.36,1.589,,63.64,OHH,-1.162,0.520039,0.00674868,0.750559 kka2_1:2_G245L,kka2_1:2_245,Kka2,kka2_1:2,P00552,0.750575,NO,245,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.812,-3.785,2.973,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.295029,0.00683899,0.750575 Pab1_G188V,Pab1_188,Pab1,Pab1,P04147,0.7506,NO,188,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.809,-3.571,2.762,,0.379,E,g,,2.18,,,,POH,-1.14633,0.175299,0.000280911,0.7506 beta-lactamase_0_H151T,beta-lactamase_0_151,TEM-1,beta-lactamase_0,P62593,0.750653,NO,151,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-2.96,-3.492,0.532,,0.594,H,A,0.17,0.1,9.375,,77.62,HBP,-2.34767,0.0500837,0.00216946,0.750653 kka2_1:8_T187G,kka2_1:8_187,Kka2,kka2_1:8,P00552,0.750671,NO,187,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.273,-3.394,2.121,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.100394,0.00693073,0.750671 kka2_1:8_T187G,kka2_1:8_187,Kka2,kka2_1:8,P00552,0.750671,NO,187,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.273,-3.394,2.121,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.100394,0.00693073,0.750671 kka2_1:2_I196M,kka2_1:2_196,Kka2,kka2_1:2,P00552,0.750675,NO,196,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-2.115,-3.213,1.098,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.295029,0.0107273,0.750675 WW_domain_T182I,WW_domain_182,Yap65,WW_domain,P46937,0.750743,NO,182,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.149,-3.337,2.188,6.20597,,,,,,,,,BPP,-1.483,0.153962,0.00294574,0.750743 beta-lactamase_0_K254R,beta-lactamase_0_254,TEM-1,beta-lactamase_0,P62593,0.750753,NO,254,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.0500837,0.00369,0.750753 kka2_1:2_K138Y,kka2_1:2_138,Kka2,kka2_1:2,P00552,0.750775,NO,138,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-2.5,-4.407,1.907,,0.594,H,A,2.34,0.98,21.038,21.038,71.59,HBB,-2.48833,0.295029,0.00628542,0.750775 beta-lactamase_0_R91Y,beta-lactamase_0_91,TEM-1,beta-lactamase_0,P62593,0.750789,NO,91,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.392,-4.246,2.854,,0.444,,B,1.2,0.96,4.557,,50.35,OBB,-1.73367,0.0500837,0.00380226,0.750789 beta-lactamase_0_W208P,beta-lactamase_0_208,TEM-1,beta-lactamase_0,P62593,0.750789,NO,208,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-0.818,-4.33,3.512,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.0500837,0.00126609,0.750789 beta-lactamase_2500_E46H,beta-lactamase_2500_46,TEM-1,beta-lactamase_2500,P62593,0.750808,NO,46,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.94,-4.828,2.888,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.361275,0.00427568,0.750808 kka2_1:8_H162D,kka2_1:8_162,Kka2,kka2_1:8,P00552,0.750882,NO,162,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-2.319,-3.685,1.366,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.100394,0.00616145,0.750882 kka2_1:8_H162D,kka2_1:8_162,Kka2,kka2_1:8,P00552,0.750882,NO,162,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-2.319,-3.685,1.366,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.100394,0.00616145,0.750882 beta-lactamase_0_E56H,beta-lactamase_0_56,TEM-1,beta-lactamase_0,P62593,0.750985,NO,56,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.043,-4.467,2.424,,0.198,E,B,1.04,0.31,1.491,,72.73,HAP,-1.94033,0.0500837,0.00238534,0.750985 kka2_1:2_E142H,kka2_1:2_142,Kka2,kka2_1:2,P00552,0.751056,NO,142,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.221,-3.221,1,,0.471,H,A,1.52,0.85,3.693,,65.53,HAB,-2.08033,0.295029,0.00748883,0.751056 beta-lactamase_625_L150H,beta-lactamase_625_150,TEM-1,beta-lactamase_625,P62593,0.751071,NO,150,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.326,-4.935,3.609,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.213352,0.00463171,0.751071 beta-lactamase_0_P250N,beta-lactamase_0_250,TEM-1,beta-lactamase_0,P62593,0.751092,NO,250,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.0500837,0.00550899,0.751092 beta-lactamase_2500_S201C,beta-lactamase_2500_201,TEM-1,beta-lactamase_2500,P62593,0.751115,NO,201,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.183,-4.753,3.57,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.361275,0.00198815,0.751115 gb1_E241P,gb1_241,gb1,gb1,P06654,0.751157,NO,241,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.672,-3.466,1.794,,,,,,,0.344,,11.83,OAP,-1.27933,0.177985,0.00250604,0.751157 gb1_V265T,gb1_265,gb1,gb1,P06654,0.751157,NO,265,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.843,-3.208,1.365,,,,,,,0.402,,11.83,OHA,-1.64567,0.177985,0.00360613,0.751157 beta-lactamase_0_D161Q,beta-lactamase_0_161,TEM-1,beta-lactamase_0,P62593,0.751159,NO,161,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.891,-3.667,2.776,,0.341,,A,0.75,-0.52,0.795,,61.19,HAB,-0.961333,0.0500837,0.000897697,0.751159 kka2_1:1_R18L,kka2_1:1_18,Kka2,kka2_1:1,P00552,0.751249,NO,18,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.055,-2.54,0.485,,0.474,T,A,1.2,0.54,11.422,11.422,71.59,ABH,-1.821,0.520039,0.00724065,0.751249 kka2_1:4_P132S,kka2_1:4_132,Kka2,kka2_1:4,P00552,0.751326,NO,132,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.775,-2.585,1.81,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.168804,0.0018489,0.751326 kka2_1:2_N200Q,kka2_1:2_200,Kka2,kka2_1:2,P00552,0.75133,NO,200,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-2.446,-2.857,0.411,,0.756,T,L,0.61,-0.08,2.836,,64.39,APO,-2.08,0.295029,0.00838549,0.75133 beta-lactamase_625_I93T,beta-lactamase_625_93,TEM-1,beta-lactamase_625,P62593,0.751331,NO,93,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.401,-2.729,1.328,,0.128,E,B,0.48,0.44,1.524,,67.83,BHB,-1.873,0.213352,0.00527066,0.751331 beta-lactamase_Y103V,beta-lactamase_103,TEM-1,beta-lactamase,P62593,0.751541,NO,103,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-1.33,-3.602,2.272,5.71734,0.613,S,l,2.55,1.21,5.721,,63.29,AHP,-1.48767,0.221079,0.00443048,0.751541 beta-lactamase_39_I261N,beta-lactamase_39_261,TEM-1,beta-lactamase_39,P62593,0.751564,NO,261,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.0495842,0.0123091,0.751564 kka2_1:2_L93P,kka2_1:2_93,Kka2,kka2_1:2,P00552,0.751594,NO,93,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.815,-4.131,3.316,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.295029,0.00131498,0.751594 kka2_1:2_E262G,kka2_1:2_262,Kka2,kka2_1:2,P00552,0.751618,NO,262,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-0.829,-3.41,2.581,,0.059,G,A,1.04,-0.18,2.383,,42.42,AAH,-0.816,0.295029,0.0191586,0.751618 beta-lactamase_0_E164M,beta-lactamase_0_164,TEM-1,beta-lactamase_0,P62593,0.751675,NO,164,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-0.948,-4.749,3.801,,0.011,T,B,1.04,-0.4,1.011,,64.69,HAO,-1.388,0.0500837,0.00137286,0.751675 beta-lactamase_0_A200D,beta-lactamase_0_200,TEM-1,beta-lactamase_0,P62593,0.751776,NO,200,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.878,-2.929,1.051,,0.757,H,A,0.46,-0.19,16.368,16.368,77.62,HHP,-2.001,0.0500837,0.0060056,0.751776 beta-lactamase_A123T,beta-lactamase_123,TEM-1,beta-lactamase,P62593,0.751891,NO,123,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.834,-3.222,2.388,4.70061,0.039,H,A,0.52,-0.72,0.705,,41.26,PHH,-1.47367,0.221079,0.0010157,0.751891 beta-lactamase_L49G,beta-lactamase_49,TEM-1,beta-lactamase,P62593,0.751891,NO,49,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.897,-3.581,1.684,5.86005,0.131,T,A,1.3,0.04,3.112,,64.69,AHP,-1.99233,0.221079,0.00401477,0.751891 beta-lactamase_0_W208K,beta-lactamase_0_208,TEM-1,beta-lactamase_0,P62593,0.751926,NO,208,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-0.818,-3.907,3.089,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.0500837,0.00126609,0.751926 beta-lactamase_0_I54R,beta-lactamase_0_54,TEM-1,beta-lactamase_0,P62593,0.751928,NO,54,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-2.838,-2.365,-0.473,,0.669,E,B,0.48,-0.14,0.541,,73.78,BHH,-2.337,0.0500837,0.00403589,0.751928 beta-lactamase_0_T187H,beta-lactamase_0_187,TEM-1,beta-lactamase_0,P62593,0.751935,NO,187,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.401,-4.688,3.287,,0.007,H,A,0.22,-1.19,3.259,,67.48,PPH,-1.69633,0.0500837,0.00491782,0.751935 beta-lactamase_L135K,beta-lactamase_135,TEM-1,beta-lactamase,P62593,0.751974,NO,135,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.002,-3.751,2.749,5.28497,0.117,H,A,1.07,-0.58,0.697,,43.71,PHH,-1.03767,0.221079,0.00244423,0.751974 kka2_1:1_R173S,kka2_1:1_173,Kka2,kka2_1:1,P00552,0.752001,NO,173,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.407,-3.482,1.075,,0.308,H,A,0.16,-0.13,14.756,14.756,65.53,HBH,-1.70533,0.520039,0.00784999,0.752001 beta-lactamase_156_A123W,beta-lactamase_156_123,TEM-1,beta-lactamase_156,P62593,0.75208,NO,123,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.834,-5.348,4.514,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.111618,0.0010157,0.75208 kka2_1:2_V83D,kka2_1:2_83,Kka2,kka2_1:2,P00552,0.752093,NO,83,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-2.567,-3.765,1.198,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.295029,0.00650486,0.752093 beta-lactamase_I45Q,beta-lactamase_45,TEM-1,beta-lactamase,P62593,0.752113,NO,45,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-2.421,-3.24,0.819,5.31505,,E,B,1,-0.3,2.256,,77.62,HHA,-2.30267,0.221079,0.00452842,0.752113 beta-lactamase_156_P143W,beta-lactamase_156_143,TEM-1,beta-lactamase_156,P62593,0.752147,NO,143,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.967,-5.497,4.53,,0.075,H,A,0.52,-0.37,0.479,,66.78,OOB,-1.354,0.111618,0.00114551,0.752147 beta-lactamase_0_D207T,beta-lactamase_0_207,TEM-1,beta-lactamase_0,P62593,0.752177,NO,207,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.064,-2.565,0.501,,0.409,H,A,0.75,0.12,5.277,,77.62,HAH,-1.77033,0.0500837,0.00592942,0.752177 beta-lactamase_0_A185Y,beta-lactamase_0_185,TEM-1,beta-lactamase_0,P62593,0.752289,NO,185,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.406,-4.227,2.821,,,H,A,0.46,-1.02,1.203,,65.03,HHP,-1.84033,0.0500837,0.00467449,0.752289 beta-lactamase_D83A,beta-lactamase_83,TEM-1,beta-lactamase,P62593,0.752309,NO,83,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.066,-3.208,2.142,5.40616,0.354,H,A,1.33,0.22,0.861,,48.95,HAH,-1.34733,0.221079,0.00205968,0.752309 kka2_1:1_L260M,kka2_1:1_260,Kka2,kka2_1:1,P00552,0.752367,NO,260,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.741,-3.833,3.092,,0.022,H,A,0.55,-0.52,,,,HHA,-0.845667,0.520039,0.0233782,0.752367 kka2_1:1_I196S,kka2_1:1_196,Kka2,kka2_1:1,P00552,0.752384,NO,196,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-2.115,-3.786,1.671,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.520039,0.0107273,0.752384 Pab1_K156T,Pab1_156,Pab1,Pab1,P04147,0.752406,NO,156,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.083,-3.239,2.156,,0.406,E,B,1.82,-0.26,,,,PBH,-1.58167,0.175299,0.000316767,0.752406 beta-lactamase_156_L191E,beta-lactamase_156_191,TEM-1,beta-lactamase_156,P62593,0.75244,NO,191,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.087,-3.859,2.772,,,H,A,0.55,0.09,1.372,,63.29,BHH,-1.445,0.111618,0.00263549,0.75244 beta-lactamase_39_V82P,beta-lactamase_39_82,TEM-1,beta-lactamase_39,P62593,0.75249,NO,82,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.325,-4.008,2.683,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.0495842,0.00397046,0.75249 beta-lactamase_156_R220P,beta-lactamase_156_220,TEM-1,beta-lactamase_156,P62593,0.752503,NO,220,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-0.942,-3.877,2.935,,0.295,I,A,1.2,-0.76,2.164,,74.48,HBP,-1.33633,0.111618,0.00232421,0.752503 kka2_1:8_L158P,kka2_1:8_158,Kka2,kka2_1:8,P00552,0.752527,NO,158,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.947,-2.892,0.945,,0.095,.,B,0.55,0.77,1.607,,63.64,AHA,-1.25333,0.100394,0.00529068,0.752527 kka2_1:8_L158P,kka2_1:8_158,Kka2,kka2_1:8,P00552,0.752527,NO,158,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.947,-2.892,0.945,,0.095,.,B,0.55,0.77,1.607,,63.64,AHA,-1.25333,0.100394,0.00529068,0.752527 beta-lactamase_2500_E87T,beta-lactamase_2500_87,TEM-1,beta-lactamase_2500,P62593,0.752544,NO,87,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.421,-2.787,1.366,,0.048,,B,1.04,0.92,17.923,17.923,64.69,PAP,-1.969,0.361275,0.00337888,0.752544 beta-lactamase_0_G154I,beta-lactamase_0_154,TEM-1,beta-lactamase_0,P62593,0.75255,NO,154,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.823,-4.173,3.35,,0.54,T,l,0.29,-0.56,3.629,,64.69,HOA,-1.635,0.0500837,0.00180205,0.75255 PSD95pdz3_G356L,PSD95pdz3_356,PSD95pdz3,PSD95pdz3,P31016,0.752659,NO,356,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.008,-3.49,2.482,4.8656,,,,,11.9575,,,,BOA,-1.22933,0.0758425,0.000623061,0.752659 gb1_F256A,gb1_256,gb1,gb1,P06654,0.752661,NO,256,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.241,-3.08,1.839,,,,,,,,,,HHB,-2.04767,0.177985,0.00435993,0.752661 gb1_G240N,gb1_240,gb1,gb1,P06654,0.752661,NO,240,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.921,-3.183,2.262,,,,,,,,,,BOA,-1.87867,0.177985,0.00270792,0.752661 kka2_1:1_L165P,kka2_1:1_165,Kka2,kka2_1:1,P00552,0.75267,NO,165,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-2.453,-3.229,0.776,,0.299,,B,1.59,1.12,2.47,,64.39,OHH,-1.90967,0.520039,0.00801161,0.75267 beta-lactamase_0_Y95C,beta-lactamase_0_95,TEM-1,beta-lactamase_0,P62593,0.752697,NO,95,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-1.715,-4.95,3.235,,0.122,,b,0.21,-0.37,2.914,,77.62,BHP,-2.16167,0.0500837,0.00479449,0.752697 kka2_1:2_A34E,kka2_1:2_34,Kka2,kka2_1:2,P00552,0.752704,NO,34,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.928,-3.441,2.513,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.295029,0.00343484,0.752704 kka2_1:2_G164V,kka2_1:2_164,Kka2,kka2_1:2,P00552,0.752716,NO,164,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.869,-3.836,2.967,,0.862,T,l,0.75,1.45,1.539,,64.39,POH,-1.828,0.295029,0.00442091,0.752716 kka2_1:4_W236L,kka2_1:4_236,Kka2,kka2_1:4,P00552,0.752787,NO,236,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-1.363,-2.199,0.836,,0.303,H,A,0.47,-0.76,2.277,,48.48,AHH,-1.81267,0.168804,0.0088796,0.752787 beta-lactamase_625_R162E,beta-lactamase_625_162,TEM-1,beta-lactamase_625,P62593,0.752926,NO,162,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.016,-3.337,2.321,,0.124,S,B,1.2,-0.37,1.445,,64.69,ABH,-1.25,0.213352,0.000561334,0.752926 beta-lactamase_0_S221F,beta-lactamase_0_221,TEM-1,beta-lactamase_0,P62593,0.752975,NO,221,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.754,-4.221,2.467,,0.624,H,A,0.27,-0.2,2.914,,74.48,BPH,-1.59967,0.0500837,0.0046094,0.752975 beta-lactamase_I11P,beta-lactamase_11,TEM-1,beta-lactamase,P62593,0.752981,NO,11,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.745,-2.653,0.908,,,,,,,3.135,,66.08,HHO,-1.79467,0.221079,0.00261325,0.752981 beta-lactamase_2500_I261C,beta-lactamase_2500_261,TEM-1,beta-lactamase_2500,P62593,0.753075,NO,261,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.361275,0.0123091,0.753075 beta-lactamase_2500_S266C,beta-lactamase_2500_266,TEM-1,beta-lactamase_2500,P62593,0.7532,NO,266,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.361275,0.0140785,0.7532 beta-lactamase_625_A215C,beta-lactamase_625_215,TEM-1,beta-lactamase_625,P62593,0.753228,NO,215,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.503,-4.816,3.313,,,,a,0.46,-0.93,3.583,,74.48,HHO,-1.42633,0.213352,0.00544007,0.753228 kka2_1:4_E111W,kka2_1:4_111,Kka2,kka2_1:4,P00552,0.753239,NO,111,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.28,-5.588,3.308,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.168804,0.00746789,0.753239 kka2_1:4_M116I,kka2_1:4_116,Kka2,kka2_1:4,P00552,0.753263,NO,116,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-2.482,-2.646,0.164,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.168804,0.00745147,0.753263 beta-lactamase_0_R162C,beta-lactamase_0_162,TEM-1,beta-lactamase_0,P62593,0.753277,NO,162,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.016,-5.08,4.064,,0.124,S,B,1.2,-0.37,1.026,,64.69,ABH,-1.25,0.0500837,0.000561334,0.753277 beta-lactamase_2500_L192T,beta-lactamase_2500_192,TEM-1,beta-lactamase_2500,P62593,0.753378,NO,192,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.254,-3.48,2.226,,0.095,H,A,0.55,0.35,1.902,,60.14,HHP,-1.41833,0.361275,0.00558728,0.753378 beta-lactamase_T179C,beta-lactamase_179,TEM-1,beta-lactamase,P62593,0.753438,NO,179,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.085,-4.712,3.627,5.07116,,E,B,0.8,-1.38,1.859,,73.08,PPH,-1.557,0.221079,0.00226045,0.753438 beta-lactamase_V21M,beta-lactamase_21,TEM-1,beta-lactamase,P62593,0.75347,NO,21,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.873,-4.268,2.395,,,,,,,0.688,,93.01,OHH,-2.09633,0.221079,0.0028612,0.75347 PSD95pdz3_I338F,PSD95pdz3_338,PSD95pdz3,PSD95pdz3,P31016,0.753494,NO,338,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.63,-3.299,1.669,5.45113,,,,,13.0087,,,,HHP,-1.55767,0.0758425,0.000862587,0.753494 kka2_1:4_D118Y,kka2_1:4_118,Kka2,kka2_1:4,P00552,0.753517,NO,118,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.07,-4.383,2.313,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.168804,0.0067852,0.753517 beta-lactamase_0_W288M,beta-lactamase_0_288,TEM-1,beta-lactamase_0,P62593,0.753539,NO,288,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,,,,,,,,,,,,,BHO,,0.0500837,,0.753539 kka2_1:1_G21S,kka2_1:1_21,Kka2,kka2_1:1,P00552,0.753595,NO,21,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.368,-2.431,1.063,,0.586,T,l,0.29,-0.75,10.291,10.291,71.59,HOH,-2.10167,0.520039,0.00709648,0.753595 kka2_1:1_P179T,kka2_1:1_179,Kka2,kka2_1:1,P00552,0.753616,NO,179,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.974,-3.471,2.497,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.520039,0.00298346,0.753616 kka2_1:1_W91C,kka2_1:1_91,Kka2,kka2_1:1,P00552,0.753625,NO,91,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-1.178,-5.004,3.826,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.520039,0.00358653,0.753625 beta-lactamase_0_L47S,beta-lactamase_0_47,TEM-1,beta-lactamase_0,P62593,0.753742,NO,47,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.876,-3.642,1.766,,0.007,E,B,0.55,0.2,1.024,,67.83,AHA,-1.639,0.0500837,0.00439844,0.753742 beta-lactamase_0_D161N,beta-lactamase_0_161,TEM-1,beta-lactamase_0,P62593,0.753744,NO,161,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.891,-3.293,2.402,,0.341,,A,0.75,-0.52,0.795,,61.19,HAB,-0.961333,0.0500837,0.000897697,0.753744 beta-lactamase_0_V31K,beta-lactamase_0_31,TEM-1,beta-lactamase_0,P62593,0.753975,NO,31,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.822,-3.873,2.051,,,H,A,0.44,-0.46,4.126,,73.78,BHB,-2.03767,0.0500837,0.00478065,0.753975 beta-lactamase_Q88P,beta-lactamase_88,TEM-1,beta-lactamase,P62593,0.754012,NO,88,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.086,-3.948,1.862,5.8056,0.807,,B,0.12,2.03,1.84,,77.62,APH,-1.53433,0.221079,0.00504167,0.754012 beta-lactamase_2500_T116L,beta-lactamase_2500_116,TEM-1,beta-lactamase_2500,P62593,0.75403,NO,116,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.28,-3.376,2.096,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.361275,0.00336175,0.75403 beta-lactamase_P181T,beta-lactamase_181,TEM-1,beta-lactamase,P62593,0.754144,NO,181,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.813,-3.419,2.606,5.14752,,H,A,1.1,-1.14,1.357,,61.54,HOH,-1.795,0.221079,0.000703122,0.754144 hsp90_M589C,hsp90_589,hsp90,hsp90,P02829,0.754151,NO,589,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-3.858,-4.015,0,4.72723,0.032,H,A,0.84,0.31,,,,PHA,-3.24233,0.368192,0.000222939,0.754151 beta-lactamase_0_P143L,beta-lactamase_0_143,TEM-1,beta-lactamase_0,P62593,0.754177,NO,143,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.967,-2.577,1.61,,0.075,H,A,0.52,-0.37,11.868,11.868,66.78,OOB,-1.354,0.0500837,0.00114551,0.754177 beta-lactamase_P249Y,beta-lactamase_249,TEM-1,beta-lactamase,P62593,0.754284,NO,249,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.312,-4.401,3.089,5.10655,0.256,S,B,0.99,0.04,0.479,,72.73,OOA,-1.81367,0.221079,0.00220169,0.754284 kka2_1:1_D159Q,kka2_1:1_159,Kka2,kka2_1:1,P00552,0.75433,NO,159,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.82,-3.79,2.97,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.520039,0.0030485,0.75433 kka2_1:4_E111F,kka2_1:4_111,Kka2,kka2_1:4,P00552,0.754349,NO,111,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.28,-4.475,2.195,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.168804,0.00746789,0.754349 kka2_1:1_Q27I,kka2_1:1_27,Kka2,kka2_1:1,P00552,0.754502,NO,27,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-1.659,-3.006,1.347,,0.608,.,A,0.64,0.71,0.521,,65.53,PPP,-1.90733,0.520039,0.00595365,0.754502 kka2_1:2_F171V,kka2_1:2_171,Kka2,kka2_1:2,P00552,0.75453,NO,171,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.326,-3.284,1.958,,0.154,H,A,0.58,-0.1,2.645,,63.64,HHH,-1.45433,0.295029,0.00821426,0.75453 beta-lactamase_0_L192I,beta-lactamase_0_192,TEM-1,beta-lactamase_0,P62593,0.754613,NO,192,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.254,-2.519,1.265,,0.095,H,A,0.55,0.35,1.756,,60.14,HHP,-1.41833,0.0500837,0.00558728,0.754613 kka2_1:1_M120I,kka2_1:1_120,Kka2,kka2_1:1,P00552,0.754646,NO,120,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-3.877,-2.912,-0.965,,,H,A,0.55,-0.42,2.259,,92.05,HHB,-2.16733,0.520039,0.00265808,0.754646 kka2_1:4_D183A,kka2_1:4_183,Kka2,kka2_1:4,P00552,0.754665,NO,183,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.204,-3.349,2.145,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.168804,0.00426304,0.754665 beta-lactamase_0_L248G,beta-lactamase_0_248,TEM-1,beta-lactamase_0,P62593,0.754789,NO,248,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.794,-3.512,1.718,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.0500837,0.00428493,0.754789 kka2_1:1_R211L,kka2_1:1_211,Kka2,kka2_1:1,P00552,0.75483,NO,211,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-0.899,-3.41,2.511,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.520039,0.00204888,0.75483 kka2_1:4_R89S,kka2_1:4_89,Kka2,kka2_1:4,P00552,0.754863,NO,89,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.548,-3.512,1.964,,0.209,E,B,1.2,1.41,4.412,,64.39,OBA,-1.89867,0.168804,0.00524373,0.754863 beta-lactamase_0_K71M,beta-lactamase_0_71,TEM-1,beta-lactamase_0,P62593,0.754938,NO,71,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-0.8,-4.48,3.68,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.0500837,0.00103192,0.754938 beta-lactamase_L49P,beta-lactamase_49,TEM-1,beta-lactamase,P62593,0.755036,NO,49,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.897,-2.49,0.593,5.86005,0.131,T,A,1.3,0.04,3.112,,64.69,AHP,-1.99233,0.221079,0.00401477,0.755036 beta-lactamase_0_K254T,beta-lactamase_0_254,TEM-1,beta-lactamase_0,P62593,0.755232,NO,254,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.0500837,0.00369,0.755232 kka2_1:2_M197R,kka2_1:2_197,Kka2,kka2_1:2,P00552,0.755291,NO,197,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.707,-4.083,2.376,,0.121,E,B,0.55,-1.19,2.097,,65.53,HHH,-1.847,0.295029,0.00921295,0.755291 kka2_1:1_A137E,kka2_1:1_137,Kka2,kka2_1:1,P00552,0.755352,NO,137,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.156,-3.863,1.707,,0.029,H,A,0.46,0.34,1.323,,63.26,PHB,-2.559,0.520039,0.00515054,0.755352 beta-lactamase_F70Q,beta-lactamase_70,TEM-1,beta-lactamase,P62593,0.755506,NO,70,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.169,-4.201,3.032,5.42055,,H,A,1.1,-1.34,1.14,,63.99,PHB,-0.980667,0.221079,0.00193499,0.755506 beta-lactamase_625_R162M,beta-lactamase_625_162,TEM-1,beta-lactamase_625,P62593,0.755513,NO,162,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.016,-4.454,3.438,,0.124,S,B,1.2,-0.37,1.445,,64.69,ABH,-1.25,0.213352,0.000561334,0.755513 beta-lactamase_0_G154A,beta-lactamase_0_154,TEM-1,beta-lactamase_0,P62593,0.755522,NO,154,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.823,-2.356,1.533,,0.54,T,l,0.29,-0.56,3.629,,64.69,HOA,-1.635,0.0500837,0.00180205,0.755522 beta-lactamase_2500_V214I,beta-lactamase_2500_214,TEM-1,beta-lactamase_2500,P62593,0.755535,NO,214,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.299,-3.053,1.754,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.361275,0.00628442,0.755535 beta-lactamase_I275C,beta-lactamase_275,TEM-1,beta-lactamase,P62593,0.755556,NO,275,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.397,-4.808,3.411,5.3999,0.015,H,A,1,-0.52,0.836,,62.59,PHH,-1.541,0.221079,0.0141984,0.755556 PSD95pdz3_L323N,PSD95pdz3_323,PSD95pdz3,PSD95pdz3,P31016,0.755607,NO,323,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.347,-3.805,2.458,5.12397,,,,,13.8825,,,,OHO,-1.121,0.0758425,0.00104644,0.755607 kka2_1:8_A117R,kka2_1:8_117,Kka2,kka2_1:8,P00552,0.755619,NO,117,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.828,-3.824,2.996,,,H,A,1.04,-0.78,0.755,,45.83,HHA,-1.79333,0.100394,0.00282984,0.755619 kka2_1:8_A117R,kka2_1:8_117,Kka2,kka2_1:8,P00552,0.755619,NO,117,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.828,-3.824,2.996,,,H,A,1.04,-0.78,0.755,,45.83,HHA,-1.79333,0.100394,0.00282984,0.755619 beta-lactamase_2500_H287V,beta-lactamase_2500_287,TEM-1,beta-lactamase_2500,P62593,0.755621,NO,287,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,,,,,,,,,,,,,BBH,-1.111,0.361275,,0.755621 kka2_1:8_R258L,kka2_1:8_258,Kka2,kka2_1:8,P00552,0.755723,NO,258,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.626,-2.791,1.165,,0.316,H,A,0.16,-0.85,5.58,,53.03,HBH,-1.25933,0.100394,0.00983174,0.755723 kka2_1:8_R258L,kka2_1:8_258,Kka2,kka2_1:8,P00552,0.755723,NO,258,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.626,-2.791,1.165,,0.316,H,A,0.16,-0.85,5.58,,53.03,HBH,-1.25933,0.100394,0.00983174,0.755723 kka2_1:4_S104L,kka2_1:4_104,Kka2,kka2_1:4,P00552,0.755735,NO,104,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.436,-3.504,2.068,,0.536,T,A,0.27,-1.11,0.357,,63.64,HPP,-1.91433,0.168804,0.00555207,0.755735 kka2_1:2_W236R,kka2_1:2_236,Kka2,kka2_1:2,P00552,0.755784,NO,236,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-1.363,-4.21,2.847,,0.303,H,A,1.51,-0.76,5.58,,48.48,AHH,-1.81267,0.295029,0.0088796,0.755784 kka2_1:2_D154C,kka2_1:2_154,Kka2,kka2_1:2,P00552,0.75579,NO,154,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.876,-5.188,4.312,,0.457,,b,0.29,1.48,3.631,,52.65,HAP,-1.52467,0.295029,0.00292633,0.75579 beta-lactamase_0_L146S,beta-lactamase_0_146,TEM-1,beta-lactamase_0,P62593,0.755797,NO,146,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.462,-2.916,1.454,,0.007,H,A,0.55,-0.56,2.051,,64.69,AHP,-1.656,0.0500837,0.00474542,0.755797 kka2_1:8_C131F,kka2_1:8_131,Kka2,kka2_1:8,P00552,0.755827,NO,131,C,F,CF,Special,Hydrophobic,5.07,3.32051,-1.74949,205,121,165,44,108.5,189.9,81.4,-0.831,-4.095,3.264,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.100394,0.00170814,0.755827 kka2_1:8_C131F,kka2_1:8_131,Kka2,kka2_1:8,P00552,0.755827,NO,131,C,F,CF,Special,Hydrophobic,5.07,3.32051,-1.74949,205,121,165,44,108.5,189.9,81.4,-0.831,-4.095,3.264,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.100394,0.00170814,0.755827 kka2_1:1_A14E,kka2_1:1_14,Kka2,kka2_1:1,P00552,0.755833,NO,14,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.837,-3.519,1.682,,0.728,G,A,0.46,0.7,1.17,,71.59,HHH,-1.82567,0.520039,0.00706614,0.755833 kka2_1:4_H188D,kka2_1:4_188,Kka2,kka2_1:4,P00552,0.755837,NO,188,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-0.913,-3.495,2.582,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.168804,0.00273139,0.755837 kka2_1:4_I196C,kka2_1:4_196,Kka2,kka2_1:4,P00552,0.755843,NO,196,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-2.115,-4.921,2.806,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.168804,0.0107273,0.755843 PSD95pdz3_A390W,PSD95pdz3_390,PSD95pdz3,PSD95pdz3,P31016,0.75585,NO,390,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.307,-5.004,3.697,5.03823,,,,,12.46,,,,HHP,-1.54467,0.0758425,0.00104603,0.75585 beta-lactamase_0_I229A,beta-lactamase_0_229,TEM-1,beta-lactamase_0,P62593,0.755906,NO,229,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.267,-3.077,1.81,,0.083,E,B,0.48,-0.76,1.69,,50,HHH,-1.58767,0.0500837,0.00477249,0.755906 beta-lactamase_0_W208T,beta-lactamase_0_208,TEM-1,beta-lactamase_0,P62593,0.755922,NO,208,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-0.818,-3.646,2.828,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.0500837,0.00126609,0.755922 kka2_1:2_A25G,kka2_1:2_25,Kka2,kka2_1:2,P00552,0.75599,NO,25,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.496,-3.533,1.037,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.295029,0.00595636,0.75599 kka2_1:4_E231G,kka2_1:4_231,Kka2,kka2_1:4,P00552,0.756006,NO,231,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.002,-3.247,1.245,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.168804,0.00732383,0.756006 kka2_1:2_S105R,kka2_1:2_105,Kka2,kka2_1:2,P00552,0.756031,NO,105,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.945,-3.214,1.269,,0.056,S,B,0.27,-1.04,3.442,,65.53,PPB,-2.17033,0.295029,0.00847233,0.756031 kka2_1:2_T72L,kka2_1:2_72,Kka2,kka2_1:2,P00552,0.756035,NO,72,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.38,-3.619,1.239,,0.784,H,A,0.82,0.29,6.463,,65.53,HPP,-2.238,0.295029,0.00750756,0.756035 kka2_1:2_E96K,kka2_1:2_96,Kka2,kka2_1:2,P00552,0.756057,NO,96,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.573,-3.494,0.921,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.295029,0.00369441,0.756057 beta-lactamase_C18P,beta-lactamase_18,TEM-1,beta-lactamase,P62593,0.756061,NO,18,C,P,CP,Special,Special,5.07,6.3,1.23,169,121,115,-6,108.5,112.7,4.2,-2.26,-2.254,-0.006,,,,,,,3.995,,93.01,HOH,-2.093,0.221079,0.002536,0.756061 kka2_1:1_A9G,kka2_1:1_9,Kka2,kka2_1:1,P00552,0.756099,NO,9,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.079,-3.28,1.201,,,,,,,0.383,,71.59,BHO,-2.253,0.520039,0.00273264,0.756099 beta-lactamase_2500_M270S,beta-lactamase_2500_270,TEM-1,beta-lactamase_2500,P62593,0.756142,NO,270,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.723,,,,0.422,H,A,1.59,1.15,2.029,,64.34,PHA,-1.70933,0.361275,0.00767762,0.756142 beta-lactamase_0_N152F,beta-lactamase_0_152,TEM-1,beta-lactamase_0,P62593,0.756151,NO,152,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-2.757,-4.363,1.606,,0.863,H,A,0.61,0.92,2.151,,77.62,BPH,-2.97,0.0500837,0.00471429,0.756151 beta-lactamase_0_H287L,beta-lactamase_0_287,TEM-1,beta-lactamase_0,P62593,0.756166,NO,287,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,,,,,,,,,,,,,BBH,-1.111,0.0500837,,0.756166 beta-lactamase_0_A235K,beta-lactamase_0_235,TEM-1,beta-lactamase_0,P62593,0.756191,NO,235,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.266,-3.575,2.309,,0.32,E,B,0.46,-0.86,2.261,,50,OHO,-0.89,0.0500837,0.00493474,0.756191 beta-lactamase_0_D207K,beta-lactamase_0_207,TEM-1,beta-lactamase_0,P62593,0.756242,NO,207,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.064,-2.897,0.833,,0.409,H,A,0.75,0.12,5.277,,77.62,HAH,-1.77033,0.0500837,0.00592942,0.756242 beta-lactamase_K30G,beta-lactamase_30,TEM-1,beta-lactamase,P62593,0.756261,NO,30,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-2.307,-3.406,1.099,5.30605,0.142,H,A,1.82,-0.65,2.434,,93.01,HBH,-2.32833,0.221079,0.00448593,0.756261 kka2_1:1_I221S,kka2_1:1_221,Kka2,kka2_1:1,P00552,0.756274,NO,221,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.739,-3.764,2.025,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.520039,0.00945908,0.756274 beta-lactamase_0_P224K,beta-lactamase_0_224,TEM-1,beta-lactamase_0,P62593,0.756291,NO,224,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.893,-3.389,2.496,,0.383,,B,0.52,-0.3,3.587,,74.48,HOH,-1.26433,0.0500837,0.00189564,0.756291 beta-lactamase_0_P172K,beta-lactamase_0_172,TEM-1,beta-lactamase_0,P62593,0.756308,NO,172,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.998,-3.522,2.524,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.0500837,0.00312594,0.756308 kka2_1:8_L193D,kka2_1:8_193,Kka2,kka2_1:8,P00552,0.756379,NO,193,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.983,-4.051,3.068,,,G,A,1.59,-1.03,2.234,,65.53,OHO,-0.965333,0.100394,0.00480179,0.756379 kka2_1:8_L193D,kka2_1:8_193,Kka2,kka2_1:8,P00552,0.756379,NO,193,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.983,-4.051,3.068,,,G,A,1.59,-1.03,2.234,,65.53,OHO,-0.965333,0.100394,0.00480179,0.756379 beta-lactamase_2500_I245C,beta-lactamase_2500_245,TEM-1,beta-lactamase_2500,P62593,0.756428,NO,245,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.361275,0.00391032,0.756428 beta-lactamase_V21Q,beta-lactamase_21,TEM-1,beta-lactamase,P62593,0.756511,NO,21,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.873,-2.763,0.89,,,,,,,0.688,,93.01,OHH,-2.09633,0.221079,0.0028612,0.756511 beta-lactamase_H110V,beta-lactamase_110,TEM-1,beta-lactamase,P62593,0.756584,NO,110,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-1.706,-3.735,2.029,5.52635,0.341,G,a,0.35,1.08,31.31,31.31,64.69,BBH,-1.73333,0.221079,0.00441499,0.756584 beta-lactamase_39_D129E,beta-lactamase_39_129,TEM-1,beta-lactamase_39,P62593,0.756617,NO,129,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.816,-2.232,1.416,,,,B,0.75,-0.69,0.56,,34.97,PAP,-0.818,0.0495842,0.00109178,0.756617 kka2_1:2_T85M,kka2_1:2_85,Kka2,kka2_1:2,P00552,0.756684,NO,85,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.165,-4.675,2.51,,0.576,E,B,0.22,1.39,1.853,,71.59,HPA,-2.10133,0.295029,0.00634493,0.756684 kka2_1:4_D52R,kka2_1:4_52,Kka2,kka2_1:4,P00552,0.756744,NO,52,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.271,-3.572,1.301,,0.22,E,B,0.75,0.8,0.349,,71.59,PAH,-2.38367,0.168804,0.00175694,0.756744 kka2_1:1_E3H,kka2_1:1_3,Kka2,kka2_1:1,P00552,0.756789,NO,3,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.199,-4.214,2.015,,,,,,,3.435,,92.05,HAP,-2.11567,0.520039,0.00267607,0.756789 kka2_1:4_I254W,kka2_1:4_254,Kka2,kka2_1:4,P00552,0.756802,NO,254,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.933,-5.273,3.34,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.168804,0.0132375,0.756802 kka2_1:8_F48S,kka2_1:8_48,Kka2,kka2_1:8,P00552,0.756827,NO,48,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.453,-3.787,2.334,,0.296,E,B,1.62,-0.99,14.194,14.194,55.3,HHH,-1.444,0.100394,0.00475422,0.756827 kka2_1:8_F48S,kka2_1:8_48,Kka2,kka2_1:8,P00552,0.756827,NO,48,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.453,-3.787,2.334,,0.296,E,B,1.62,-0.99,14.194,14.194,55.3,HHH,-1.444,0.100394,0.00475422,0.756827 kka2_1:2_P109V,kka2_1:2_109,Kka2,kka2_1:2,P00552,0.756841,NO,109,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.412,-2.937,1.525,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.295029,0.0070929,0.756841 beta-lactamase_0_L192R,beta-lactamase_0_192,TEM-1,beta-lactamase_0,P62593,0.756972,NO,192,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.254,-4.095,2.841,,0.095,H,A,0.55,0.35,1.756,,60.14,HHP,-1.41833,0.0500837,0.00558728,0.756972 beta-lactamase_2500_G39Y,beta-lactamase_2500_39,TEM-1,beta-lactamase_2500,P62593,0.757013,NO,39,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.864,-4.383,2.519,,0.701,T,L,0.29,0.47,29.926,29.926,77.62,HOH,-1.53633,0.361275,0.00487611,0.757013 beta-lactamase_625_L100A,beta-lactamase_625_100,TEM-1,beta-lactamase_625,P62593,0.757049,NO,100,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.218,-3.158,1.94,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.213352,0.00413885,0.757049 kka2_1:1_V214L,kka2_1:1_214,Kka2,kka2_1:1,P00552,0.757072,NO,214,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.261,-2.012,0.751,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.520039,0.00692782,0.757072 kka2_1:1_Q136K,kka2_1:1_136,Kka2,kka2_1:1,P00552,0.757089,NO,136,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-3.021,-3.273,0.252,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.520039,0.00624149,0.757089 gb1_T242D,gb1_242,gb1,gb1,P06654,0.75709,NO,242,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.245,-3.204,1.959,,,,,,,,,,APP,-1.444,0.177985,0.00243886,0.75709 beta-lactamase_0_G141N,beta-lactamase_0_141,TEM-1,beta-lactamase_0,P62593,0.757101,NO,141,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.828,-3.472,2.644,,0.575,T,l,0.29,-0.28,0.722,,64.69,HOO,-1.08933,0.0500837,0.0012419,0.757101 beta-lactamase_0_R59V,beta-lactamase_0_59,TEM-1,beta-lactamase_0,P62593,0.757149,NO,59,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.345,-3.76,2.415,,0.329,S,L,1.2,-0.09,2.919,,73.08,HBO,-2.24267,0.0500837,0.00318082,0.757149 kka2_1:4_C192N,kka2_1:4_192,Kka2,kka2_1:4,P00552,0.757162,NO,192,C,N,CN,Special,Polar,5.07,5.47157,0.401575,139,121,132,11,108.5,114.1,5.6,-1.067,-3.983,2.916,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.168804,0.00485428,0.757162 beta-lactamase_39_V259H,beta-lactamase_39_259,TEM-1,beta-lactamase_39,P62593,0.757185,NO,259,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.0495842,0.0070773,0.757185 beta-lactamase_0_Y103K,beta-lactamase_0_103,TEM-1,beta-lactamase_0,P62593,0.757218,NO,103,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-1.33,-3.666,2.336,,0.613,S,l,0.21,1.21,1.646,,63.29,AHP,-1.48767,0.0500837,0.00443048,0.757218 kka2_1:1_L70P,kka2_1:1_70,Kka2,kka2_1:1,P00552,0.757252,NO,70,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.017,-4.164,3.147,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.520039,0.00411884,0.757252 Pab1_F149C,Pab1_149,Pab1,Pab1,P04147,0.757252,NO,149,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.149,-4.679,3.53,,0.183,T,A,1.33,1.09,,,,HHO,-1.27767,0.175299,0.000325688,0.757252 beta-lactamase_0_R63F,beta-lactamase_0_63,TEM-1,beta-lactamase_0,P62593,0.757319,NO,63,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-0.943,-4.214,3.271,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.0500837,0.00126938,0.757319 beta-lactamase_G236T,beta-lactamase_236,TEM-1,beta-lactamase,P62593,0.757359,NO,236,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.784,-3.55,2.766,4.7915,0.241,,b,0.23,-0.59,1.883,,64.69,HOA,-1.36933,0.221079,0.00162372,0.757359 kka2_1:8_L184S,kka2_1:8_184,Kka2,kka2_1:8,P00552,0.757378,NO,184,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.496,-3.717,2.221,,0.489,E,B,0.55,-0.06,4.495,,63.26,AHH,-1.24833,0.100394,0.00518742,0.757378 kka2_1:8_L184S,kka2_1:8_184,Kka2,kka2_1:8,P00552,0.757378,NO,184,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.496,-3.717,2.221,,0.489,E,B,0.55,-0.06,4.495,,63.26,AHH,-1.24833,0.100394,0.00518742,0.757378 beta-lactamase_156_G240Q,beta-lactamase_156_240,TEM-1,beta-lactamase_156,P62593,0.757384,NO,240,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.111618,0.00591201,0.757384 beta-lactamase_2500_V106Y,beta-lactamase_2500_106,TEM-1,beta-lactamase_2500,P62593,0.757509,NO,106,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.218,-3.895,2.677,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.361275,0.00304168,0.757509 kka2_1:4_K112Q,kka2_1:4_112,Kka2,kka2_1:4,P00552,0.757532,NO,112,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-2.491,-2.826,0.335,,0.076,H,A,2.34,-1.37,0.39,,56.06,ABH,-2.00133,0.168804,0.00645389,0.757532 kka2_1:4_P194Q,kka2_1:4_194,Kka2,kka2_1:4,P00552,0.757574,NO,194,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.846,-3.927,3.081,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.168804,0.00314194,0.757574 beta-lactamase_0_A34C,beta-lactamase_0_34,TEM-1,beta-lactamase_0,P62593,0.757585,NO,34,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.059,-4.764,2.705,,,H,A,0.46,-0.54,3.998,,73.78,AHA,-1.74967,0.0500837,0.00407913,0.757585 beta-lactamase_2500_H24F,beta-lactamase_2500_24,TEM-1,beta-lactamase_2500,P62593,0.757765,NO,24,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-2.481,-4.152,1.671,,,,,,,0.467,,93.01,OBO,-2.0035,0.361275,0.00238894,0.757765 beta-lactamase_0_G281N,beta-lactamase_0_281,TEM-1,beta-lactamase_0,P62593,0.757769,NO,281,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.0500837,0.0406482,0.757769 beta-lactamase_0_V260D,beta-lactamase_0_260,TEM-1,beta-lactamase_0,P62593,0.757804,NO,260,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.0500837,0.00471757,0.757804 gb1_G240A,gb1_240,gb1,gb1,P06654,0.757816,NO,240,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.921,-2.588,1.667,,,,,,,,,,BOA,-1.87867,0.177985,0.00270792,0.757816 beta-lactamase_39_L167K,beta-lactamase_39_167,TEM-1,beta-lactamase_39,P62593,0.757827,NO,167,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.138,-3.594,2.456,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.0495842,0.00303566,0.757827 beta-lactamase_625_G154Y,beta-lactamase_625_154,TEM-1,beta-lactamase_625,P62593,0.757833,NO,154,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.823,-4.424,3.601,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.213352,0.00180205,0.757833 kka2_1:8_M148W,kka2_1:8_148,Kka2,kka2_1:8,P00552,0.757844,NO,148,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.847,-5.364,3.517,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.100394,0.00982664,0.757844 kka2_1:8_M148W,kka2_1:8_148,Kka2,kka2_1:8,P00552,0.757844,NO,148,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.847,-5.364,3.517,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.100394,0.00982664,0.757844 beta-lactamase_156_L74Q,beta-lactamase_156_74,TEM-1,beta-lactamase_156,P62593,0.75792,NO,74,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.296,-4.107,2.811,,,H,A,0.55,-0.91,0.746,,50,HHO,-1.34933,0.111618,0.00493255,0.75792 beta-lactamase_0_T139A,beta-lactamase_0_139,TEM-1,beta-lactamase_0,P62593,0.758,NO,139,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.901,-2.031,0.13,,0.216,H,A,0.22,0.39,0.421,,77.62,PPH,-2.04667,0.0500837,0.00441837,0.758 kka2_1:1_V16G,kka2_1:1_16,Kka2,kka2_1:1,P00552,0.758,NO,16,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-3.087,-2.751,-0.336,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.520039,0.00694011,0.758 Ubiquitin_E64R,Ubiquitin_64,Uba1,Ubiquitin,P0CG48,0.758065,NO,64,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.763,-3.808,2.045,5.084,0.54,T,l,,0.79,,,,BAP,-1.64433,0.205827,0.000817406,0.758065 Ubiquitin_F4I,Ubiquitin_4,Uba1,Ubiquitin,P0CG48,0.758065,NO,4,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.534,-3.476,1.942,4.77459,0.059,E,B,,-0.46,,,,HHH,-1.504,0.205827,0.000805043,0.758065 Ubiquitin_Q49C,Ubiquitin_49,Uba1,Ubiquitin,P0CG48,0.758065,NO,49,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-1.941,-3.292,1.351,5.05026,0.403,E,B,,-0.59,,,,BPH,-1.49467,0.205827,0.000613067,0.758065 Ubiquitin_Y59V,Ubiquitin_59,Uba1,Ubiquitin,P0CG48,0.758065,NO,59,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-1.307,-2.703,1.396,5.05599,0.072,G,A,0.43,-0.74,2.566,,24.53,AHP,-1.568,0.205827,0.000775084,0.758065 PSD95pdz3_L367N,PSD95pdz3_367,PSD95pdz3,PSD95pdz3,P31016,0.758068,NO,367,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.347,-3.805,2.458,5.47696,,,,,17.0063,,,,AHB,-1.39767,0.0758425,0.000466436,0.758068 WW_domain_T198R,WW_domain_198,Yap65,WW_domain,P46937,0.758093,NO,198,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.451,-3.68,2.229,5.14348,,,,,,3.158,,70.04,PPH,-1.513,0.153962,0.00224534,0.758093 kka2_1:8_E262G,kka2_1:8_262,Kka2,kka2_1:8,P00552,0.7581,NO,262,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-0.829,-3.41,2.581,,0.059,G,A,1.52,-0.18,0.837,,42.42,AAH,-0.816,0.100394,0.0191586,0.7581 kka2_1:8_E262G,kka2_1:8_262,Kka2,kka2_1:8,P00552,0.7581,NO,262,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-0.829,-3.41,2.581,,0.059,G,A,1.52,-0.18,0.837,,42.42,AAH,-0.816,0.100394,0.0191586,0.7581 kka2_1:1_G201C,kka2_1:1_201,Kka2,kka2_1:1,P00552,0.758155,NO,201,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.56,-3.58,2.02,,0.149,T,l,0.29,-0.57,16.092,16.092,52.65,POB,-1.92233,0.520039,0.00820117,0.758155 kka2_1:2_D62Y,kka2_1:2_62,Kka2,kka2_1:2,P00552,0.75816,NO,62,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.591,-4.391,2.8,,0.262,H,A,0.75,0.08,10.048,10.048,64.39,PAA,-1.77833,0.295029,0.00744243,0.75816 kka2_1:1_A137Q,kka2_1:1_137,Kka2,kka2_1:1,P00552,0.758176,NO,137,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.156,-4.203,2.047,,0.029,H,A,0.46,0.34,1.323,,63.26,PHB,-2.559,0.520039,0.00515054,0.758176 kka2_1:1_A41G,kka2_1:1_41,Kka2,kka2_1:1,P00552,0.758224,NO,41,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.879,-2.32,0.441,,0.184,.,B,0.46,-0.96,18.207,18.207,64.39,PHP,-2.477,0.520039,0.00543332,0.758224 beta-lactamase_0_V82M,beta-lactamase_0_82,TEM-1,beta-lactamase_0,P62593,0.758251,NO,82,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.325,-4.274,2.949,,0.267,H,A,0.44,0.08,1.893,,93.01,BHA,-1.28567,0.0500837,0.00397046,0.758251 kka2_1:1_E149G,kka2_1:1_149,Kka2,kka2_1:1,P00552,0.758264,NO,149,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.994,-3.566,1.572,,0.674,H,A,1.04,1.63,3.671,,71.59,HAH,-1.59667,0.520039,0.00803343,0.758264 kka2_1:4_D90K,kka2_1:4_90,Kka2,kka2_1:4,P00552,0.758307,NO,90,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.459,-3.563,1.104,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.168804,0.00583842,0.758307 beta-lactamase_0_V259N,beta-lactamase_0_259,TEM-1,beta-lactamase_0,P62593,0.758327,NO,259,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.0500837,0.0070773,0.758327 beta-lactamase_N130C,beta-lactamase_130,TEM-1,beta-lactamase,P62593,0.758399,NO,130,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-0.798,-5.087,4.289,5.26686,0.069,H,A,1.08,-0.74,,,,APP,-0.980667,0.221079,0.000683376,0.758399 beta-lactamase_T131F,beta-lactamase_131,TEM-1,beta-lactamase,P62593,0.758399,NO,131,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.328,-4.204,2.876,5.0548,,H,A,0.53,-0.69,3.306,,67.48,PPH,-1.00867,0.221079,0.00345886,0.758399 beta-lactamase_0_I125Y,beta-lactamase_0_125,TEM-1,beta-lactamase_0,P62593,0.7584,NO,125,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.441,-4.111,2.67,,,H,A,0.48,-0.7,1.874,,63.29,HHP,-1.248,0.0500837,0.00383964,0.7584 beta-lactamase_625_T69C,beta-lactamase_625_69,TEM-1,beta-lactamase_625,P62593,0.758424,NO,69,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-0.973,-4.661,3.688,,,G,A,0.22,-1.24,2.716,,93.01,PPH,-1.01833,0.213352,0.00127498,0.758424 beta-lactamase_0_E26T,beta-lactamase_0_26,TEM-1,beta-lactamase_0,P62593,0.758427,NO,26,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.454,-2.753,0.299,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.0500837,0.00297948,0.758427 beta-lactamase_T69C,beta-lactamase_69,TEM-1,beta-lactamase,P62593,0.758457,NO,69,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-0.973,-4.661,3.688,5.16042,,G,A,0.69,-1.24,0.505,,93.01,PPH,-1.01833,0.221079,0.00127498,0.758457 beta-lactamase_G52L,beta-lactamase_52,TEM-1,beta-lactamase,P62593,0.758462,NO,52,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.149,-3.755,2.606,5.12093,0.299,,l,0.77,-0.04,2.103,,64.69,POB,-1.66267,0.221079,0.00340138,0.758462 kka2_1:4_R145M,kka2_1:4_145,Kka2,kka2_1:4,P00552,0.758485,NO,145,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.804,-4.748,2.944,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.168804,0.00846663,0.758485 beta-lactamase_0_E56Q,beta-lactamase_0_56,TEM-1,beta-lactamase_0,P62593,0.758522,NO,56,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.043,-3.697,1.654,,0.198,E,B,1.04,0.31,1.491,,72.73,HAP,-1.94033,0.0500837,0.00238534,0.758522 beta-lactamase_0_K254Q,beta-lactamase_0_254,TEM-1,beta-lactamase_0,P62593,0.758531,NO,254,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.0500837,0.00369,0.758531 gb1_G240C,gb1_240,gb1,gb1,P06654,0.758539,NO,240,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.921,-4.823,3.902,,,,,,,,,,BOA,-1.87867,0.177985,0.00270792,0.758539 gb1_L231G,gb1_231,gb1,gb1,P06654,0.758539,NO,231,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.603,-3.5,1.897,,,,,,,0.219,,11.83,BHH,-1.82633,0.177985,0.00322797,0.758539 beta-lactamase_625_T178A,beta-lactamase_625_178,TEM-1,beta-lactamase_625,P62593,0.75858,NO,178,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-0.791,-2.853,2.062,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.213352,0.000684366,0.75858 beta-lactamase_L197Q,beta-lactamase_197,TEM-1,beta-lactamase,P62593,0.758593,NO,197,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.853,-4.122,3.269,5.19172,0.007,S,B,1.3,0.33,1.756,,60.14,HHP,-1.833,0.221079,0.00144602,0.758593 beta-lactamase_L205F,beta-lactamase_205,TEM-1,beta-lactamase,P62593,0.758593,NO,205,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.922,-2.306,1.384,5.67023,,H,A,1.3,-0.46,0.678,,42.31,PHH,-1.57767,0.221079,0.00255802,0.758593 beta-lactamase_L197H,beta-lactamase_197,TEM-1,beta-lactamase,P62593,0.758675,NO,197,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.853,-4.903,4.05,5.19172,0.007,S,B,1.3,0.33,1.756,,60.14,HHP,-1.833,0.221079,0.00144602,0.758675 beta-lactamase_0_T69Y,beta-lactamase_0_69,TEM-1,beta-lactamase_0,P62593,0.758723,NO,69,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-0.973,-4.223,3.25,,,G,A,0.22,-1.24,0.505,,93.01,PPH,-1.01833,0.0500837,0.00127498,0.758723 beta-lactamase_0_K32G,beta-lactamase_0_32,TEM-1,beta-lactamase_0,P62593,0.758738,NO,32,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.984,-3.506,1.522,,0.563,H,A,2.34,0.34,0.418,,73.08,HBA,-2.04233,0.0500837,0.00401283,0.758738 beta-lactamase_0_K71F,beta-lactamase_0_71,TEM-1,beta-lactamase_0,P62593,0.758793,NO,71,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-0.8,-4.292,3.492,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.0500837,0.00103192,0.758793 kka2_1:1_F206V,kka2_1:1_206,Kka2,kka2_1:1,P00552,0.758833,NO,206,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.349,-2.691,1.342,,0.006,E,B,0.58,-1.21,0.978,,63.64,OHH,-1.04,0.520039,0.00936868,0.758833 kka2_1:1_A41D,kka2_1:1_41,Kka2,kka2_1:1,P00552,0.758935,NO,41,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.879,-3.164,1.285,,0.184,.,B,0.46,-0.96,18.207,18.207,64.39,PHP,-2.477,0.520039,0.00543332,0.758935 kka2_1:2_A78T,kka2_1:2_78,Kka2,kka2_1:2,P00552,0.759033,NO,78,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.744,-3.425,1.681,,0.078,.,B,0.46,-0.53,0.206,,56.06,OHH,-1.863,0.295029,0.00457299,0.759033 kka2_1:1_G43A,kka2_1:1_43,Kka2,kka2_1:1,P00552,0.759046,NO,43,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.587,-2.77,1.183,,0.862,T,l,0.75,-0.67,2.247,,63.26,POB,-2.18533,0.520039,0.0071925,0.759046 beta-lactamase_I283H,beta-lactamase_283,TEM-1,beta-lactamase,P62593,0.759048,NO,283,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.638,-4.895,3.257,5.4178,0.165,H,A,1.23,0.04,1.576,,69.23,HHB,-1.735,0.221079,0.0429138,0.759048 kka2_1:4_V198L,kka2_1:4_198,Kka2,kka2_1:4,P00552,0.75905,NO,198,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.719,-3.148,1.429,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.168804,0.00835002,0.75905 beta-lactamase_N272A,beta-lactamase_272,TEM-1,beta-lactamase,P62593,0.759171,NO,272,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-1.127,-3.333,2.206,5.37826,0.081,H,A,0.09,-0.97,1.468,,63.64,BPB,-1.56333,0.221079,0.00545371,0.759171 beta-lactamase_2500_D48S,beta-lactamase_2500_48,TEM-1,beta-lactamase_2500,P62593,0.759174,NO,48,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.101,-3.25,2.149,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.361275,0.0027273,0.759174 gb1_N263A,gb1_263,gb1,gb1,P06654,0.759259,NO,263,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-1.162,-3.08,1.918,,,,,,,,,,APO,-2.04233,0.177985,0.0035297,0.759259 kka2_1:2_L243P,kka2_1:2_243,Kka2,kka2_1:2,P00552,0.759364,NO,243,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-2.651,-4.123,1.472,,0.277,H,A,1.59,-0.67,13.165,13.165,92.05,HHH,-2.03767,0.295029,0.00884927,0.759364 beta-lactamase_A245T,beta-lactamase_245,TEM-1,beta-lactamase,P62593,0.759499,NO,245,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.068,-3.315,2.247,4.78972,,E,B,0.17,-0.92,0.831,,64.69,HHH,-1.58133,0.221079,0.00391032,0.759499 kka2_1:4_L102R,kka2_1:4_102,Kka2,kka2_1:4,P00552,0.759535,NO,102,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.804,-3.959,3.155,,,T,A,0.55,-1.17,0.65,,42.42,AHH,-1.398,0.168804,0.00201332,0.759535 kka2_1:1_W69L,kka2_1:1_69,Kka2,kka2_1:1,P00552,0.759566,NO,69,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-0.859,-3.385,2.526,,0.164,H,A,0.47,0.15,5.074,,38.64,PHH,-1.49967,0.520039,0.0012874,0.759566 beta-lactamase_Y103T,beta-lactamase_103,TEM-1,beta-lactamase,P62593,0.759615,NO,103,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-1.33,-3.696,2.366,5.71734,0.613,S,l,2.55,1.21,5.721,,63.29,AHP,-1.48767,0.221079,0.00443048,0.759615 kka2_1:8_R38Y,kka2_1:8_38,Kka2,kka2_1:8,P00552,0.759678,NO,38,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.207,-4.179,2.972,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.100394,0.00372499,0.759678 kka2_1:8_R38Y,kka2_1:8_38,Kka2,kka2_1:8,P00552,0.759678,NO,38,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.207,-4.179,2.972,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.100394,0.00372499,0.759678 PSD95pdz3_D357K,PSD95pdz3_357,PSD95pdz3,PSD95pdz3,P31016,0.759707,NO,357,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.264,-3.139,1.875,5.22306,,,,,10.975,,,,OAP,-1.32367,0.0758425,0.000609015,0.759707 beta-lactamase_0_E119K,beta-lactamase_0_119,TEM-1,beta-lactamase_0,P62593,0.759739,NO,119,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.412,-3.343,1.931,,0.358,H,A,1.04,0.51,3.396,,63.99,BAH,-1.623,0.0500837,0.00386966,0.759739 beta-lactamase_0_S128T,beta-lactamase_0_128,TEM-1,beta-lactamase_0,P62593,0.759791,NO,128,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-0.84,-2.971,2.131,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.0500837,0.00071483,0.759791 beta-lactamase_T107M,beta-lactamase_107,TEM-1,beta-lactamase,P62593,0.759869,NO,107,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.117,-4.531,3.414,5.23432,,G,A,2.12,-0.06,3.676,,67.83,HPA,-1.265,0.221079,0.00239347,0.759869 kka2_1:2_R121C,kka2_1:2_121,Kka2,kka2_1:2,P00552,0.75991,NO,121,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.552,-5.157,3.605,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.295029,0.00523326,0.75991 kka2_1:8_L232V,kka2_1:8_232,Kka2,kka2_1:8,P00552,0.759914,NO,232,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.514,-2.443,0.929,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.100394,0.00800103,0.759914 kka2_1:8_L232V,kka2_1:8_232,Kka2,kka2_1:8,P00552,0.759914,NO,232,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.514,-2.443,0.929,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.100394,0.00800103,0.759914 beta-lactamase_A40L,beta-lactamase_40,TEM-1,beta-lactamase,P62593,0.759955,NO,40,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.402,-3.399,1.997,4.9697,0.155,S,B,1.2,0.21,1.714,,73.78,OHB,-1.40267,0.221079,0.00490026,0.759955 kka2_1:8_C192Y,kka2_1:8_192,Kka2,kka2_1:8,P00552,0.760016,NO,192,C,Y,CY,Special,Hydrophobic,5.07,5.66,0.59,194,121,181,60,108.5,193.6,85.1,-1.067,-2.934,1.867,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.100394,0.00485428,0.760016 kka2_1:8_C192Y,kka2_1:8_192,Kka2,kka2_1:8,P00552,0.760016,NO,192,C,Y,CY,Special,Hydrophobic,5.07,5.66,0.59,194,121,181,60,108.5,193.6,85.1,-1.067,-2.934,1.867,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.100394,0.00485428,0.760016 kka2_1:4_R253S,kka2_1:4_253,Kka2,kka2_1:4,P00552,0.760026,NO,253,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.356,-3.389,2.033,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.168804,0.0144195,0.760026 kka2_1:4_L259V,kka2_1:4_259,Kka2,kka2_1:4,P00552,0.76003,NO,259,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.088,-2.47,1.382,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.168804,0.0206964,0.76003 kka2_1:2_K138G,kka2_1:2_138,Kka2,kka2_1:2,P00552,0.760179,NO,138,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-2.5,-2.938,0.438,,0.594,H,A,2.34,0.98,21.038,21.038,71.59,HBB,-2.48833,0.295029,0.00628542,0.760179 beta-lactamase_0_L135C,beta-lactamase_0_135,TEM-1,beta-lactamase_0,P62593,0.76019,NO,135,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.002,-4.691,3.689,,0.117,H,A,0.55,-0.58,0.705,,43.71,PHH,-1.03767,0.0500837,0.00244423,0.76019 beta-lactamase_2500_A211W,beta-lactamase_2500_211,TEM-1,beta-lactamase_2500,P62593,0.760191,NO,211,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.896,-5.506,3.61,,0.369,T,A,0.46,-0.69,2.061,,77.62,AHA,-1.94633,0.361275,0.00648183,0.760191 kka2_1:2_A34Q,kka2_1:2_34,Kka2,kka2_1:2,P00552,0.760323,NO,34,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.928,-3.9,2.972,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.295029,0.00343484,0.760323 E1_Ubiquitin_L43P,E1_Ubiquitin_43,Uba1,E1_Ubiquitin,P0CG63,0.760389,NO,43,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.188,-3.845,2.657,,,E,B,,-1.17,,,,BHH,-1.30733,0.18783,0.00190185,0.760389 beta-lactamase_0_A282E,beta-lactamase_0_282,TEM-1,beta-lactamase_0,P62593,0.760402,NO,282,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.0500837,0.0449821,0.760402 beta-lactamase_V21H,beta-lactamase_21,TEM-1,beta-lactamase,P62593,0.760417,NO,21,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.873,-4.673,2.8,,,,,,,0.688,,93.01,OHH,-2.09633,0.221079,0.0028612,0.760417 kka2_1:2_E230V,kka2_1:2_230,Kka2,kka2_1:2,P00552,0.760456,NO,230,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.672,-3.108,0.436,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.295029,0.00920051,0.760456 kka2_1:2_L123V,kka2_1:2_123,Kka2,kka2_1:2,P00552,0.760626,NO,123,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.888,-2.888,2,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.295029,0.00325188,0.760626 gb1_Y259I,gb1_259,gb1,gb1,P06654,0.76069,NO,259,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-1.78,-3.422,1.642,,,,,,,0.131,,11.83,PHH,-1.787,0.177985,0.00464313,0.76069 beta-lactamase_625_N168I,beta-lactamase_625_168,TEM-1,beta-lactamase_625,P62593,0.760837,NO,168,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-1.029,-3.943,2.914,,0.113,G,A,0.61,-0.4,1.014,,44.41,HPA,-1.13233,0.213352,0.00288667,0.760837 beta-lactamase_625_F58E,beta-lactamase_625_58,TEM-1,beta-lactamase_625,P62593,0.76086,NO,58,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-2.914,-3.579,0.665,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.213352,0.00523369,0.76086 Pab1_A179P,Pab1_179,Pab1,Pab1,P04147,0.760861,NO,179,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.013,-3.472,2.459,,0.078,H,A,0.61,0.5,,,,HHB,-1.51233,0.175299,0.000291703,0.760861 kka2_1:4_F256A,kka2_1:4_256,Kka2,kka2_1:4,P00552,0.760893,NO,256,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.49,-3.439,1.949,,,H,A,0.58,-0.78,1.653,,53.03,HHH,-1.423,0.168804,0.0132841,0.760893 PSD95pdz3_D348L,PSD95pdz3_348,PSD95pdz3,PSD95pdz3,P31016,0.760898,NO,348,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.264,-3.49,2.226,5.02473,,,,,16.8925,,,,HAH,-1.306,0.0758425,0.000731866,0.760898 kka2_1:4_E96M,kka2_1:4_96,Kka2,kka2_1:4,P00552,0.760983,NO,96,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.573,-4.64,2.067,,0.476,,B,1.52,-0.65,1.254,,71.59,OAH,-2.143,0.168804,0.00369441,0.760983 beta-lactamase_0_E56M,beta-lactamase_0_56,TEM-1,beta-lactamase_0,P62593,0.760993,NO,56,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.043,-4.624,2.581,,0.198,E,B,1.04,0.31,1.491,,72.73,HAP,-1.94033,0.0500837,0.00238534,0.760993 kka2_1:1_W15C,kka2_1:1_15,Kka2,kka2_1:1,P00552,0.760994,NO,15,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-1.392,-4.882,3.49,,0.01,G,A,0.47,0.15,20.149,20.149,52.27,HHH,-2.10533,0.520039,0.00585505,0.760994 kka2_1:2_V46L,kka2_1:2_46,Kka2,kka2_1:2,P00552,0.761006,NO,46,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-2.62,-3.558,0.938,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.295029,0.00631301,0.761006 kka2_1:8_L259H,kka2_1:8_259,Kka2,kka2_1:8,P00552,0.761073,NO,259,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.088,-4.939,3.851,,0.036,H,A,1.59,-0.15,1.83,,48.48,BHH,-1.15167,0.100394,0.0206964,0.761073 kka2_1:8_L259H,kka2_1:8_259,Kka2,kka2_1:8,P00552,0.761073,NO,259,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.088,-4.939,3.851,,0.036,H,A,1.59,-0.15,1.83,,48.48,BHH,-1.15167,0.100394,0.0206964,0.761073 beta-lactamase_2500_P60Y,beta-lactamase_2500_60,TEM-1,beta-lactamase_2500,P62593,0.761107,NO,60,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-2.469,-4.292,1.823,,0.256,T,A,0.52,-0.56,1.581,,77.62,BOA,-1.97633,0.361275,0.00521318,0.761107 beta-lactamase_0_G141D,beta-lactamase_0_141,TEM-1,beta-lactamase_0,P62593,0.761183,NO,141,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.828,-2.284,1.456,,0.575,T,l,0.29,-0.28,0.722,,64.69,HOO,-1.08933,0.0500837,0.0012419,0.761183 kka2_1:1_P179Q,kka2_1:1_179,Kka2,kka2_1:1,P00552,0.761237,NO,179,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.974,-4.023,3.049,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.520039,0.00298346,0.761237 beta-lactamase_R81D,beta-lactamase_81,TEM-1,beta-lactamase,P62593,0.761301,NO,81,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.466,-3.611,2.145,5.12166,0.218,H,A,0.68,1.66,1.236,,50,PBH,-1.60667,0.221079,0.00499763,0.761301 beta-lactamase_2500_L55K,beta-lactamase_2500_55,TEM-1,beta-lactamase_2500,P62593,0.761423,NO,55,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.86,-3.791,1.931,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.361275,0.00403741,0.761423 beta-lactamase_D83G,beta-lactamase_83,TEM-1,beta-lactamase,P62593,0.761546,NO,83,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.066,-2.429,1.363,5.40616,0.354,H,A,1.33,0.22,0.861,,48.95,HAH,-1.34733,0.221079,0.00205968,0.761546 Pab1_K156W,Pab1_156,Pab1,Pab1,P04147,0.761563,NO,156,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.083,-5.14,4.057,,0.406,E,B,1.82,-0.26,,,,PBH,-1.58167,0.175299,0.000316767,0.761563 beta-lactamase_G76M,beta-lactamase_76,TEM-1,beta-lactamase,P62593,0.761614,NO,76,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.189,-4.767,3.578,4.73862,,H,A,2.05,-0.67,3.059,,67.83,OOH,-1.22267,0.221079,0.00476637,0.761614 kka2_1:1_T73A,kka2_1:1_73,Kka2,kka2_1:1,P00552,0.76163,NO,73,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.51,-2.502,-0.008,,0.309,H,A,0.22,0.35,4.126,,56.06,PPO,-2.02333,0.520039,0.00628605,0.76163 kka2_1:4_T72I,kka2_1:4_72,Kka2,kka2_1:4,P00552,0.761651,NO,72,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.38,-4.117,1.737,,0.784,H,A,0.82,0.29,6.463,,65.53,HPP,-2.238,0.168804,0.00750756,0.761651 kka2_1:8_G213C,kka2_1:8_213,Kka2,kka2_1:8,P00552,0.761854,NO,213,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.596,-5.115,4.519,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.100394,0.00187654,0.761854 kka2_1:8_G213C,kka2_1:8_213,Kka2,kka2_1:8,P00552,0.761854,NO,213,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.596,-5.115,4.519,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.100394,0.00187654,0.761854 beta-lactamase_0_L89V,beta-lactamase_0_89,TEM-1,beta-lactamase_0,P62593,0.761972,NO,89,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.096,-3.043,1.947,,0.168,T,A,0.55,0.63,2.373,,64.34,PHO,-1.75767,0.0500837,0.00207068,0.761972 beta-lactamase_L89Q,beta-lactamase_89,TEM-1,beta-lactamase,P62593,0.762006,NO,89,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.096,-4.086,2.99,5.41092,0.168,T,A,1.75,0.63,1.599,,64.34,PHO,-1.75767,0.221079,0.00207068,0.762006 beta-lactamase_2500_V101N,beta-lactamase_2500_101,TEM-1,beta-lactamase_2500,P62593,0.762016,NO,101,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.295,-4.085,2.79,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.361275,0.00374492,0.762016 PSD95pdz3_I336K,PSD95pdz3_336,PSD95pdz3,PSD95pdz3,P31016,0.762032,NO,336,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.63,-3.589,1.959,5.11321,,,,,13.6363,,,,OHH,-1.38733,0.0758425,0.000887923,0.762032 kka2_1:2_G88C,kka2_1:2_88,Kka2,kka2_1:2,P00552,0.762086,NO,88,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.689,-5.252,3.563,,0.54,S,l,0.75,1.51,2.814,,65.53,HOB,-1.718,0.295029,0.00685559,0.762086 gb1_L238T,gb1_238,gb1,gb1,P06654,0.762107,NO,238,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-2.98,-3.352,0.372,,,,,,,0.504,,45.54,PHB,-2.58633,0.177985,0.00205885,0.762107 kka2_1:8_G233C,kka2_1:8_233,Kka2,kka2_1:8,P00552,0.762125,NO,233,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.748,-5.16,4.412,,0.172,,b,0.75,-0.27,1.134,,49.24,HOO,-1.72067,0.100394,0.00232366,0.762125 kka2_1:8_G233C,kka2_1:8_233,Kka2,kka2_1:8,P00552,0.762125,NO,233,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.748,-5.16,4.412,,0.172,,b,0.75,-0.27,1.134,,49.24,HOO,-1.72067,0.100394,0.00232366,0.762125 kka2_1:2_L19C,kka2_1:2_19,Kka2,kka2_1:2,P00552,0.762156,NO,19,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.254,-4.888,3.634,,0.08,T,A,0.55,-0.26,17.165,17.165,65.53,BHH,-2.221,0.295029,0.00620703,0.762156 beta-lactamase_0_G85C,beta-lactamase_0_85,TEM-1,beta-lactamase_0,P62593,0.762177,NO,85,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.011,-5.172,4.161,,0.805,T,l,0.29,1.7,2.25,,63.64,HOP,-1.68733,0.0500837,0.00252173,0.762177 beta-lactamase_F17R,beta-lactamase_17,TEM-1,beta-lactamase,P62593,0.762333,NO,17,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-2.337,-4.028,1.691,,,,,,,2.192,,67.83,HHO,-2.17733,0.221079,0.00216499,0.762333 beta-lactamase_625_C121I,beta-lactamase_625_121,TEM-1,beta-lactamase_625,P62593,0.762336,NO,121,C,I,CI,Special,Hydrophobic,5.07,6.02,0.95,198,121,131,10,108.5,166.7,58.2,-0.953,-3.628,2.675,,,H,A,0.46,-0.81,1.143,,63.29,HOP,-1.46767,0.213352,0.000744322,0.762336 beta-lactamase_L150Q,beta-lactamase_150,TEM-1,beta-lactamase,P62593,0.762368,NO,150,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.326,-4.106,2.78,5.15566,,H,A,1.75,-0.2,1.615,,62.94,HHB,-1.86167,0.221079,0.00463171,0.762368 kka2_1:1_R143S,kka2_1:1_143,Kka2,kka2_1:1,P00552,0.762369,NO,143,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.525,-3.022,0.497,,0.325,H,A,0.16,1.22,3.6,,65.53,ABH,-1.86833,0.520039,0.00662247,0.762369 kka2_1:1_R202S,kka2_1:1_202,Kka2,kka2_1:1,P00552,0.762415,NO,202,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.761,-2.977,1.216,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.520039,0.00696498,0.762415 beta-lactamase_156_Y95S,beta-lactamase_156_95,TEM-1,beta-lactamase_156,P62593,0.762423,NO,95,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-1.715,-3.776,2.061,,0.122,,b,0.21,-0.37,2.341,,77.62,BHP,-2.16167,0.111618,0.00479449,0.762423 kka2_1:1_P132Q,kka2_1:1_132,Kka2,kka2_1:1,P00552,0.762475,NO,132,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.775,-3.926,3.151,,0.692,.,A,0.52,0.56,0.224,,44.7,OOH,-0.825667,0.520039,0.0018489,0.762475 beta-lactamase_L218C,beta-lactamase_218,TEM-1,beta-lactamase,P62593,0.762508,NO,218,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.391,-4.928,3.537,4.88972,,I,b,2.89,-0.53,12.788,12.788,74.48,OHH,-1.58867,0.221079,0.00618274,0.762508 kka2_1:1_R66S,kka2_1:1_66,Kka2,kka2_1:1,P00552,0.762574,NO,66,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-0.922,-3.412,2.49,,0.103,H,A,1.2,-0.2,2.659,,46.21,HBH,-1.13567,0.520039,0.00161025,0.762574 kka2_1:4_R239C,kka2_1:4_239,Kka2,kka2_1:4,P00552,0.762579,NO,239,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.949,-5.104,2.155,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.168804,0.00835326,0.762579 kka2_1:4_E59D,kka2_1:4_59,Kka2,kka2_1:4,P00552,0.762608,NO,59,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-0.952,-2.395,1.443,,0.187,.,L,1.04,0.62,3.408,,50.38,PAH,-1.53,0.168804,0.00280355,0.762608 beta-lactamase_39_M184W,beta-lactamase_39_184,TEM-1,beta-lactamase_39,P62593,0.762621,NO,184,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.593,-5.149,3.556,,,H,A,0.55,-0.87,2.893,,62.94,HHH,-1.41,0.0495842,0.00356019,0.762621 kka2_1:2_F37H,kka2_1:2_37,Kka2,kka2_1:2,P00552,0.762626,NO,37,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.427,-2.73,1.303,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.295029,0.00586193,0.762626 beta-lactamase_0_G141C,beta-lactamase_0_141,TEM-1,beta-lactamase_0,P62593,0.762636,NO,141,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.828,-5.167,4.339,,0.575,T,l,0.29,-0.28,0.722,,64.69,HOO,-1.08933,0.0500837,0.0012419,0.762636 kka2_1:8_W236G,kka2_1:8_236,Kka2,kka2_1:8,P00552,0.762701,NO,236,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-1.363,-2.755,1.392,,0.303,H,A,1.51,-0.76,1.87,,48.48,AHH,-1.81267,0.100394,0.0088796,0.762701 kka2_1:8_W236G,kka2_1:8_236,Kka2,kka2_1:8,P00552,0.762701,NO,236,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-1.363,-2.755,1.392,,0.303,H,A,1.51,-0.76,1.87,,48.48,AHH,-1.81267,0.100394,0.0088796,0.762701 kka2_1:2_S204G,kka2_1:2_204,Kka2,kka2_1:2,P00552,0.762708,NO,204,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.353,-2.544,1.191,,0.144,E,A,0.27,-1.2,2.442,,65.53,HPO,-0.953333,0.295029,0.00881794,0.762708 beta-lactamase_F70N,beta-lactamase_70,TEM-1,beta-lactamase,P62593,0.762748,NO,70,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.169,-4.034,2.865,5.42055,,H,A,1.1,-1.34,1.14,,63.99,PHB,-0.980667,0.221079,0.00193499,0.762748 gb1_V280G,gb1_280,gb1,gb1,P06654,0.762812,NO,280,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.764,-3.178,1.414,,,,,,,0.874,,35.71,PHP,-1.63733,0.177985,0.00321577,0.762812 beta-lactamase_0_Q97M,beta-lactamase_0_97,TEM-1,beta-lactamase_0,P62593,0.762813,NO,97,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.072,-3.413,1.341,,0.823,G,A,0.64,2.42,16.954,16.954,77.62,PPP,-2.43833,0.0500837,0.0045116,0.762813 kka2_1:2_V198S,kka2_1:2_198,Kka2,kka2_1:2,P00552,0.762853,NO,198,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.719,-2.746,1.027,,0.05,E,B,1.48,-0.95,1.074,,56.06,HHA,-1.88667,0.295029,0.00835002,0.762853 kka2_1:2_E86K,kka2_1:2_86,Kka2,kka2_1:2,P00552,0.762955,NO,86,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.86,-3.566,1.706,,0.369,.,B,1.04,1.92,3.573,,63.26,PAH,-1.98067,0.295029,0.00642858,0.762955 beta-lactamase_V257M,beta-lactamase_257,TEM-1,beta-lactamase,P62593,0.762972,NO,257,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.533,-4.236,2.703,5.31999,,E,B,0.96,-0.7,1.463,,58.74,HHH,-1.70967,0.221079,0.00756629,0.762972 beta-lactamase_2500_L100F,beta-lactamase_2500_100,TEM-1,beta-lactamase_2500,P62593,0.763089,NO,100,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.218,-3.677,2.459,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.361275,0.00413885,0.763089 beta-lactamase_V21Y,beta-lactamase_21,TEM-1,beta-lactamase,P62593,0.763091,NO,21,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.873,-4.085,2.212,,,,,,,0.688,,93.01,OHH,-2.09633,0.221079,0.0028612,0.763091 PSD95pdz3_A390E,PSD95pdz3_390,PSD95pdz3,PSD95pdz3,P31016,0.763097,NO,390,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.307,-3.122,1.815,5.03823,,,,,12.46,,,,HHP,-1.54467,0.0758425,0.00104603,0.763097 PSD95pdz3_E373R,PSD95pdz3_373,PSD95pdz3,PSD95pdz3,P31016,0.763141,NO,373,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.404,-3.165,1.761,5.79743,,,,,27.9833,,,,BAP,-1.57667,0.0758425,0.000387698,0.763141 beta-lactamase_L223R,beta-lactamase_223,TEM-1,beta-lactamase,P62593,0.763143,NO,223,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.055,-4.022,2.967,5.42318,0.27,,B,1.3,0.09,1.511,,74.48,HHO,-1.35033,0.221079,0.00372793,0.763143 kka2_1:1_E17D,kka2_1:1_17,Kka2,kka2_1:1,P00552,0.763182,NO,17,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.154,-2.384,0.23,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.520039,0.00688738,0.763182 beta-lactamase_L150N,beta-lactamase_150,TEM-1,beta-lactamase,P62593,0.763233,NO,150,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.326,-4.088,2.762,5.15566,,H,A,1.75,-0.2,1.615,,62.94,HHB,-1.86167,0.221079,0.00463171,0.763233 beta-lactamase_0_S96H,beta-lactamase_0_96,TEM-1,beta-lactamase_0,P62593,0.763275,NO,96,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.27,-3.418,1.148,,0.368,,b,0.27,0.39,2.516,,73.78,HPP,-2.019,0.0500837,0.00551835,0.763275 beta-lactamase_625_L197A,beta-lactamase_625_197,TEM-1,beta-lactamase_625,P62593,0.76343,NO,197,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.853,-2.357,1.504,,0.007,S,B,0.55,0.33,1.756,,60.14,HHP,-1.833,0.213352,0.00144602,0.76343 beta-lactamase_0_M127Y,beta-lactamase_0_127,TEM-1,beta-lactamase_0,P62593,0.763468,NO,127,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-2.251,-2.954,0.703,,0.312,S,A,0.55,0.32,9.35,9.35,72.73,PHP,-1.40433,0.0500837,0.00437927,0.763468 kka2_1:2_G164F,kka2_1:2_164,Kka2,kka2_1:2,P00552,0.763479,NO,164,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.869,-4.375,3.506,,0.862,T,l,0.75,1.45,1.539,,64.39,POH,-1.828,0.295029,0.00442091,0.763479 beta-lactamase_C121I,beta-lactamase_121,TEM-1,beta-lactamase,P62593,0.76365,NO,121,C,I,CI,Special,Hydrophobic,5.07,6.02,0.95,198,121,131,10,108.5,166.7,58.2,-0.953,-3.628,2.675,5.12205,,H,A,2.8,-0.81,7.644,,63.29,HOP,-1.46767,0.221079,0.000744322,0.76365 beta-lactamase_I243F,beta-lactamase_243,TEM-1,beta-lactamase,P62593,0.763677,NO,243,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.532,-3.988,2.456,5.26886,,E,B,1.68,-1.24,2.289,,50,OHH,-1.46867,0.221079,0.00464034,0.763677 kka2_1:4_L102P,kka2_1:4_102,Kka2,kka2_1:4,P00552,0.763702,NO,102,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.804,-4.131,3.327,,,T,A,0.55,-1.17,0.65,,42.42,AHH,-1.398,0.168804,0.00201332,0.763702 WW_domain_G176N,WW_domain_176,Yap65,WW_domain,P46937,0.763711,NO,176,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.235,-3.42,2.185,6.33142,,,,,,2.71,,78.57,HOH,-1.35467,0.153962,0.00288552,0.763711 beta-lactamase_0_E35H,beta-lactamase_0_35,TEM-1,beta-lactamase_0,P62593,0.763737,NO,35,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-0.869,-4.279,3.41,,0.15,H,A,1.04,0.21,0.664,,46.85,HAA,-1.88667,0.0500837,0.00174441,0.763737 beta-lactamase_625_G265W,beta-lactamase_625_265,TEM-1,beta-lactamase_625,P62593,0.763803,NO,265,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.213352,0.00811926,0.763803 beta-lactamase_0_T186P,beta-lactamase_0_186,TEM-1,beta-lactamase_0,P62593,0.763855,NO,186,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.522,-3.945,1.423,,0.396,H,A,0.22,-0.28,16.606,16.606,77.62,HPP,-1.77633,0.0500837,0.00485034,0.763855 kka2_1:2_P76H,kka2_1:2_76,Kka2,kka2_1:2,P00552,0.763856,NO,76,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.449,-4.835,3.386,,0.331,.,B,0.52,-0.41,0.345,,63.64,HOO,-1.662,0.295029,0.00625685,0.763856 kka2_1:1_C192G,kka2_1:1_192,Kka2,kka2_1:1,P00552,0.763899,NO,192,C,G,CG,Special,Special,5.07,3.29388,-1.77612,159,121,75,-46,108.5,60.1,-48.4,-1.067,-3.557,2.49,,0.095,.,B,0.46,-0.75,2.749,,50,HOH,-0.960333,0.520039,0.00485428,0.763899 beta-lactamase_0_W227E,beta-lactamase_0_227,TEM-1,beta-lactamase_0,P62593,0.763919,NO,227,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-0.982,-3.914,2.932,,0.272,,B,0.47,-0.29,3.782,,74.48,OHH,-1.595,0.0500837,0.00226019,0.763919 kka2_1:1_Q163H,kka2_1:1_163,Kka2,kka2_1:1,P00552,0.763926,NO,163,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.162,-4.775,2.613,,0.58,T,B,0.64,1.85,2.779,,64.02,BPO,-1.78333,0.520039,0.00719507,0.763926 kka2_1:2_W69L,kka2_1:2_69,Kka2,kka2_1:2,P00552,0.763935,NO,69,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-0.859,-3.385,2.526,,0.164,H,A,0.47,0.15,5.074,,38.64,PHH,-1.49967,0.295029,0.0012874,0.763935 kka2_1:2_D190L,kka2_1:2_190,Kka2,kka2_1:2,P00552,0.763943,NO,190,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.708,-3.836,3.128,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.295029,0.00247989,0.763943 beta-lactamase_T262G,beta-lactamase_262,TEM-1,beta-lactamase,P62593,0.763968,NO,262,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.332,-2.493,1.161,5.06002,0.108,E,B,0.3,-0.55,1.423,,67.83,PPO,-2.081,0.221079,0.00853516,0.763968 kka2_1:4_W69C,kka2_1:4_69,Kka2,kka2_1:4,P00552,0.764052,NO,69,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-0.859,-4.914,4.055,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.168804,0.0012874,0.764052 gb1_E282G,gb1_282,gb1,gb1,P06654,0.764211,NO,282,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.318,-3.048,1.73,,,,,,,1.075,,35.71,PAO,-1.573,0.177985,0.00209643,0.764211 kka2_1:2_D154T,kka2_1:2_154,Kka2,kka2_1:2,P00552,0.764231,NO,154,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.876,-3.472,2.596,,0.457,,b,0.29,1.48,3.631,,52.65,HAP,-1.52467,0.295029,0.00292633,0.764231 kka2_1:4_L57P,kka2_1:4_57,Kka2,kka2_1:4,P00552,0.764295,NO,57,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.898,-3.173,1.275,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.168804,0.00723769,0.764295 kka2_1:2_A150S,kka2_1:2_150,Kka2,kka2_1:2,P00552,0.764315,NO,150,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.949,-3.097,2.148,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.295029,0.0045009,0.764315 beta-lactamase_0_H156K,beta-lactamase_0_156,TEM-1,beta-lactamase_0,P62593,0.76434,NO,156,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-3.156,-2.967,-0.189,,0.753,S,A,0.17,-0.6,23.367,23.367,77.62,ABH,-1.932,0.0500837,0.00468596,0.76434 kka2_1:2_Y244H,kka2_1:2_244,Kka2,kka2_1:2,P00552,0.764346,NO,244,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-0.775,-3.808,3.033,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.295029,0.00453187,0.764346 WW_domain_A180T,WW_domain_180,Yap65,WW_domain,P46937,0.764376,NO,180,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.242,-1.989,0.747,6.02829,,,,,,0.627,,23.61,HHB,-1.37767,0.153962,0.00413929,0.764376 beta-lactamase_2500_R202E,beta-lactamase_2500_202,TEM-1,beta-lactamase_2500,P62593,0.764426,NO,202,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.292,-3.173,1.881,,0.188,H,A,1.2,0.62,3.734,,77.62,PBP,-1.54767,0.361275,0.00321899,0.764426 beta-lactamase_0_D83K,beta-lactamase_0_83,TEM-1,beta-lactamase_0,P62593,0.764468,NO,83,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.066,-3.429,2.363,,0.354,H,A,0.75,0.22,0.617,,48.95,HAH,-1.34733,0.0500837,0.00205968,0.764468 kka2_1:2_V75F,kka2_1:2_75,Kka2,kka2_1:2,P00552,0.764469,NO,75,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-2.06,-2.827,0.767,,0.042,.,B,0.44,-0.2,2.815,,71.59,OHO,-1.563,0.295029,0.00693733,0.764469 beta-lactamase_625_A235Q,beta-lactamase_625_235,TEM-1,beta-lactamase_625,P62593,0.764544,NO,235,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.266,-4.018,2.752,,0.32,E,B,0.46,-0.86,0.281,,50,OHO,-0.89,0.213352,0.00493474,0.764544 beta-lactamase_39_I258Q,beta-lactamase_39_258,TEM-1,beta-lactamase_39,P62593,0.764688,NO,258,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.0495842,0.007931,0.764688 WW_domain_G185M,WW_domain_185,Yap65,WW_domain,P46937,0.764715,NO,185,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.861,-4.707,3.846,6.22337,,,,,,,,,POP,-1.194,0.153962,0.00199178,0.764715 kka2_1:2_E111R,kka2_1:2_111,Kka2,kka2_1:2,P00552,0.764787,NO,111,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.28,-2.316,0.036,,0.155,H,A,1.52,-1.14,2.792,,65.53,HAB,-2.27833,0.295029,0.00746789,0.764787 beta-lactamase_E35S,beta-lactamase_35,TEM-1,beta-lactamase,P62593,0.764855,NO,35,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-0.869,-3.186,2.317,5.10723,0.15,H,A,0.52,0.21,1.081,,46.85,HAA,-1.88667,0.221079,0.00174441,0.764855 kka2_1:2_R44E,kka2_1:2_44,Kka2,kka2_1:2,P00552,0.764902,NO,44,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.062,-2.778,0.716,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.295029,0.00745043,0.764902 beta-lactamase_625_E56W,beta-lactamase_625_56,TEM-1,beta-lactamase_625,P62593,0.764904,NO,56,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.043,-5.293,3.25,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.213352,0.00238534,0.764904 beta-lactamase_K32D,beta-lactamase_32,TEM-1,beta-lactamase,P62593,0.764946,NO,32,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.984,-2.882,0.898,5.55842,0.563,H,A,1.82,0.34,1.754,,73.08,HBA,-2.04233,0.221079,0.00401283,0.764946 beta-lactamase_2500_G85Y,beta-lactamase_2500_85,TEM-1,beta-lactamase_2500,P62593,0.76496,NO,85,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.011,-4.409,3.398,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.361275,0.00252173,0.76496 beta-lactamase_0_L89H,beta-lactamase_0_89,TEM-1,beta-lactamase_0,P62593,0.765054,NO,89,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.096,-4.892,3.796,,0.168,T,A,0.55,0.63,2.373,,64.34,PHO,-1.75767,0.0500837,0.00207068,0.765054 beta-lactamase_0_K32E,beta-lactamase_0_32,TEM-1,beta-lactamase_0,P62593,0.765133,NO,32,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.984,-2.418,0.434,,0.563,H,A,2.34,0.34,0.418,,73.08,HBA,-2.04233,0.0500837,0.00401283,0.765133 beta-lactamase_T158A,beta-lactamase_158,TEM-1,beta-lactamase,P62593,0.765218,NO,158,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.116,-2.879,1.763,5.32011,0.036,,B,0.98,-0.85,2.755,,69.58,HPB,-1.269,0.221079,0.00341825,0.765218 kka2_1:4_A255P,kka2_1:4_255,Kka2,kka2_1:4,P00552,0.765239,NO,255,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.715,-3.184,1.469,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.168804,0.0126809,0.765239 beta-lactamase_0_G39N,beta-lactamase_0_39,TEM-1,beta-lactamase_0,P62593,0.765259,NO,39,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.864,-2.55,0.686,,0.701,T,L,0.29,0.47,4.111,,77.62,HOH,-1.53633,0.0500837,0.00487611,0.765259 kka2_1:2_V84G,kka2_1:2_84,Kka2,kka2_1:2,P00552,0.76527,NO,84,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-2.279,-3.558,1.279,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.295029,0.00724019,0.76527 kka2_1:1_P45H,kka2_1:1_45,Kka2,kka2_1:1,P00552,0.765294,NO,45,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.774,-4.807,3.033,,0.669,.,B,0.52,-0.76,4.882,,71.59,BOH,-2.152,0.520039,0.00590481,0.765294 kka2_1:1_G30S,kka2_1:1_30,Kka2,kka2_1:1,P00552,0.76532,NO,30,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.596,-3.189,2.593,,0.54,S,g,0.29,3.76,,,,HOO,-1.51133,0.520039,0.00159208,0.76532 beta-lactamase_D36P,beta-lactamase_36,TEM-1,beta-lactamase,P62593,0.765406,NO,36,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.732,-3.967,1.235,5.39764,0.555,H,A,0.11,1.17,13.689,13.689,77.62,AAP,-1.91167,0.221079,0.00476483,0.765406 kka2_1:4_E96L,kka2_1:4_96,Kka2,kka2_1:4,P00552,0.765415,NO,96,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.573,-3.338,0.765,,0.476,,B,1.52,-0.65,1.254,,71.59,OAH,-2.143,0.168804,0.00369441,0.765415 beta-lactamase_0_T139L,beta-lactamase_0_139,TEM-1,beta-lactamase_0,P62593,0.765527,NO,139,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.901,-3.419,1.518,,0.216,H,A,0.22,0.39,0.421,,77.62,PPH,-2.04667,0.0500837,0.00441837,0.765527 kka2_1:2_D118N,kka2_1:2_118,Kka2,kka2_1:2,P00552,0.765534,NO,118,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.07,-3.163,1.093,,0.61,H,A,0.75,-0.05,2.237,,64.39,HAH,-1.32367,0.295029,0.0067852,0.765534 kka2_1:4_R211L,kka2_1:4_211,Kka2,kka2_1:4,P00552,0.765569,NO,211,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-0.899,-3.41,2.511,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.168804,0.00204888,0.765569 gb1_A252P,gb1_252,gb1,gb1,P06654,0.765598,NO,252,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.175,-3.39,2.215,,,,,,,,,,PHA,-1.55967,0.177985,0.00125598,0.765598 gb1_Q258F,gb1_258,gb1,gb1,P06654,0.765598,NO,258,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.095,-4.152,2.057,,,,,,,0.86,,37.28,BPH,-1.88333,0.177985,0.00437595,0.765598 kka2_1:1_Q100P,kka2_1:1_100,Kka2,kka2_1:1,P00552,0.765608,NO,100,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.77,-4.125,1.355,,0.646,E,B,0.4,-0.79,15.116,15.116,71.59,OPA,-1.46467,0.520039,0.0066405,0.765608 beta-lactamase_A246N,beta-lactamase_246,TEM-1,beta-lactamase,P62593,0.765636,NO,246,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.121,-4.23,2.109,4.78979,0.01,E,B,0.52,-1.01,1.26,,73.78,HHH,-1.55633,0.221079,0.00569458,0.765636 beta-lactamase_S104N,beta-lactamase_104,TEM-1,beta-lactamase,P62593,0.765687,NO,104,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.015,-3.421,2.406,4.92365,0.04,,b,0.82,0.57,4.02,,63.29,HPO,-1.05267,0.221079,0.00218083,0.765687 hsp90_G584W,hsp90_584,hsp90,hsp90,P02829,0.765714,NO,584,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-2.511,-4.251,0,5.20094,0.414,S,b,0.84,0.33,,,,HOH,-3.32733,0.368192,0.000222939,0.765714 beta-lactamase_39_V72E,beta-lactamase_39_72,TEM-1,beta-lactamase_39,P62593,0.765747,NO,72,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.658,-3.755,2.097,,,H,A,0.44,-1.03,1.92,,65.73,BHH,-1.32167,0.0495842,0.00501194,0.765747 kka2_1:1_A117E,kka2_1:1_117,Kka2,kka2_1:1,P00552,0.765748,NO,117,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.828,-3.532,2.704,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.520039,0.00282984,0.765748 beta-lactamase_625_G281I,beta-lactamase_625_281,TEM-1,beta-lactamase_625,P62593,0.765769,NO,281,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.213352,0.0406482,0.765769 beta-lactamase_E87W,beta-lactamase_87,TEM-1,beta-lactamase,P62593,0.76582,NO,87,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.421,-5.437,4.016,5.41929,0.048,,B,0.52,0.92,1.754,,64.69,PAP,-1.969,0.221079,0.00337888,0.76582 PSD95pdz3_V328H,PSD95pdz3_328,PSD95pdz3,PSD95pdz3,P31016,0.765858,NO,328,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.465,-4.587,3.122,5.28275,,,,,16.8775,,,,HHO,-1.36767,0.0758425,0.000986706,0.765858 Pab1_K156A,Pab1_156,Pab1,Pab1,P04147,0.765877,NO,156,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.083,-2.895,1.812,,0.406,E,B,1.82,-0.26,,,,PBH,-1.58167,0.175299,0.000316767,0.765877 kka2_1:1_L94P,kka2_1:1_94,Kka2,kka2_1:1,P00552,0.765921,NO,94,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.618,-4.098,2.48,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.520039,0.00520888,0.765921 Pab1_N139K,Pab1_139,Pab1,Pab1,P04147,0.765932,NO,139,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-1.079,-3.049,1.97,,0.062,H,A,,-0.73,,,,APB,-1.09667,0.175299,0.000339145,0.765932 beta-lactamase_R255L,beta-lactamase_255,TEM-1,beta-lactamase,P62593,0.76594,NO,255,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.266,-2.025,-0.241,5.55882,0.141,E,B,0.68,0.38,1.199,,63.99,PBH,-2.00433,0.221079,0.00499612,0.76594 beta-lactamase_L100W,beta-lactamase_100,TEM-1,beta-lactamase,P62593,0.766012,NO,100,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.218,-5.168,3.95,5.60291,0.343,,B,1.3,0.13,1.173,,63.29,AHH,-1.23467,0.221079,0.00413885,0.766012 kka2_1:1_A172D,kka2_1:1_172,Kka2,kka2_1:1,P00552,0.766062,NO,172,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.757,-2.549,0.792,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.520039,0.0079265,0.766062 beta-lactamase_625_I45H,beta-lactamase_625_45,TEM-1,beta-lactamase_625,P62593,0.766068,NO,45,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-2.421,-3.408,0.987,,,E,B,0.48,-0.3,3.642,,77.62,HHA,-2.30267,0.213352,0.00452842,0.766068 beta-lactamase_0_L192N,beta-lactamase_0_192,TEM-1,beta-lactamase_0,P62593,0.766102,NO,192,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.254,-4.206,2.952,,0.095,H,A,0.55,0.35,1.756,,60.14,HHP,-1.41833,0.0500837,0.00558728,0.766102 beta-lactamase_0_P250I,beta-lactamase_0_250,TEM-1,beta-lactamase_0,P62593,0.766111,NO,250,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.0500837,0.00550899,0.766111 Ubiquitin_N60P,Ubiquitin_60,Uba1,Ubiquitin,P0CG48,0.766129,NO,60,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-1.775,-3.001,1.226,5.00332,0.775,T,L,,0.33,,,,HPH,-1.532,0.205827,0.000814061,0.766129 kka2_1:1_W91L,kka2_1:1_91,Kka2,kka2_1:1,P00552,0.766188,NO,91,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-1.178,-3.365,2.187,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.520039,0.00358653,0.766188 beta-lactamase_0_I171S,beta-lactamase_0_171,TEM-1,beta-lactamase_0,P62593,0.766265,NO,171,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-2.431,-2.869,0.438,,0.361,,B,0.48,0.53,16.954,16.954,77.62,HHO,-1.55533,0.0500837,0.00623355,0.766265 gb1_K257R,gb1_257,gb1,gb1,P06654,0.766287,NO,257,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.775,-1.895,0.12,,,,,,,0.896,,37.28,HBP,-1.70367,0.177985,0.00640304,0.766287 PSD95pdz3_D357W,PSD95pdz3_357,PSD95pdz3,PSD95pdz3,P31016,0.7663,NO,357,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.264,-5.229,3.965,5.22306,,,,,10.975,,,,OAP,-1.32367,0.0758425,0.000609015,0.7663 beta-lactamase_P105Y,beta-lactamase_105,TEM-1,beta-lactamase,P62593,0.766313,NO,105,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.813,-4.385,3.572,5.08236,0.226,T,A,0.98,0.8,1.154,,63.29,POH,-1.01533,0.221079,0.0011981,0.766313 beta-lactamase_0_A215I,beta-lactamase_0_215,TEM-1,beta-lactamase_0,P62593,0.766329,NO,215,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.503,-3.916,2.413,,,,a,0.46,-0.93,0.494,,74.48,HHO,-1.42633,0.0500837,0.00544007,0.766329 kka2_1:2_D250K,kka2_1:2_250,Kka2,kka2_1:2,P00552,0.766333,NO,250,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.015,-3.438,2.423,,0.274,.,b,0.75,-0.46,3.796,,51.89,OAP,-1.83933,0.295029,0.0177103,0.766333 beta-lactamase_0_L150F,beta-lactamase_0_150,TEM-1,beta-lactamase_0,P62593,0.766338,NO,150,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.326,-3.884,2.558,,,H,A,0.55,-0.2,2.128,,62.94,HHB,-1.86167,0.0500837,0.00463171,0.766338 kka2_1:1_L93M,kka2_1:1_93,Kka2,kka2_1:1,P00552,0.766381,NO,93,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.815,-3.907,3.092,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.520039,0.00131498,0.766381 beta-lactamase_0_T186E,beta-lactamase_0_186,TEM-1,beta-lactamase_0,P62593,0.766393,NO,186,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.522,-2.494,-0.028,,0.396,H,A,0.22,-0.28,16.606,16.606,77.62,HPP,-1.77633,0.0500837,0.00485034,0.766393 kka2_1:4_A71L,kka2_1:4_71,Kka2,kka2_1:4,P00552,0.766417,NO,71,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.824,-3.593,1.769,,0.553,H,A,0.46,0.08,5.76,,64.39,HHP,-1.74033,0.168804,0.00727707,0.766417 kka2_1:1_W69C,kka2_1:1_69,Kka2,kka2_1:1,P00552,0.766593,NO,69,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-0.859,-4.914,4.055,,0.164,H,A,0.47,0.15,5.074,,38.64,PHH,-1.49967,0.520039,0.0012874,0.766593 kka2_1:8_S32R,kka2_1:8_32,Kka2,kka2_1:8,P00552,0.766637,NO,32,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-0.804,-3.736,2.932,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.100394,0.00149998,0.766637 kka2_1:8_S32R,kka2_1:8_32,Kka2,kka2_1:8,P00552,0.766637,NO,32,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-0.804,-3.736,2.932,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.100394,0.00149998,0.766637 beta-lactamase_2500_L111R,beta-lactamase_2500_111,TEM-1,beta-lactamase_2500,P62593,0.766712,NO,111,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.76,-4.077,2.317,,0.328,T,A,0.55,0.93,1.966,,64.34,BHP,-1.884,0.361275,0.00480671,0.766712 beta-lactamase_M115T,beta-lactamase_115,TEM-1,beta-lactamase,P62593,0.766771,NO,115,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.389,-3.522,2.133,4.89743,0.019,E,B,1.3,0.08,1.236,,69.58,OHP,-1.25433,0.221079,0.0034337,0.766771 kka2_1:1_L158M,kka2_1:1_158,Kka2,kka2_1:1,P00552,0.766803,NO,158,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.947,-4.254,2.307,,0.095,.,B,0.55,0.77,7.588,,63.64,AHA,-1.25333,0.520039,0.00529068,0.766803 beta-lactamase_0_P25K,beta-lactamase_0_25,TEM-1,beta-lactamase_0,P62593,0.766883,NO,25,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.526,-3.426,1.9,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.0500837,0.00347571,0.766883 beta-lactamase_D48T,beta-lactamase_48,TEM-1,beta-lactamase,P62593,0.766932,NO,48,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.101,-3.511,2.41,4.89966,0.189,E,B,0.23,0.21,1.281,,50.35,HAH,-1.62467,0.221079,0.0027273,0.766932 kka2_1:4_R253G,kka2_1:4_253,Kka2,kka2_1:4,P00552,0.766951,NO,253,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.356,-3.453,2.097,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.168804,0.0144195,0.766951 kka2_1:2_T72N,kka2_1:2_72,Kka2,kka2_1:2,P00552,0.766959,NO,72,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.38,-3.767,1.387,,0.784,H,A,0.82,0.29,6.463,,65.53,HPP,-2.238,0.295029,0.00750756,0.766959 kka2_1:2_W236C,kka2_1:2_236,Kka2,kka2_1:2,P00552,0.766965,NO,236,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-1.363,-3.273,1.91,,0.303,H,A,1.51,-0.76,5.58,,48.48,AHH,-1.81267,0.295029,0.0088796,0.766965 gb1_Y271I,gb1_271,gb1,gb1,P06654,0.766973,NO,271,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-1.181,-3.337,2.156,,,,,,,,,,PHA,-1.92933,0.177985,0.00236544,0.766973 beta-lactamase_G141T,beta-lactamase_141,TEM-1,beta-lactamase,P62593,0.767091,NO,141,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.828,-3.647,2.819,5.03155,0.575,T,l,0.76,-0.28,0.198,,64.69,HOO,-1.08933,0.221079,0.0012419,0.767091 beta-lactamase_0_I125A,beta-lactamase_0_125,TEM-1,beta-lactamase_0,P62593,0.767131,NO,125,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.441,-3.138,1.697,,,H,A,0.48,-0.7,1.874,,63.29,HHP,-1.248,0.0500837,0.00383964,0.767131 beta-lactamase_0_T69D,beta-lactamase_0_69,TEM-1,beta-lactamase_0,P62593,0.767268,NO,69,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-0.973,-3.534,2.561,,,G,A,0.22,-1.24,0.505,,93.01,PPH,-1.01833,0.0500837,0.00127498,0.767268 WW_domain_S183D,WW_domain_183,Yap65,WW_domain,P46937,0.767303,NO,183,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.95,-3.382,1.432,5.35576,,,,,,1.594,,83.93,PPP,-1.48733,0.153962,0.00445513,0.767303 kka2_1:2_K175P,kka2_1:2_175,Kka2,kka2_1:2,P00552,0.767374,NO,175,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-2.897,-4.168,1.271,,0.579,H,A,1.3,0.51,15.629,15.629,71.59,HBH,-1.82333,0.295029,0.00693093,0.767374 WW_domain_Q200E,WW_domain_200,Yap65,WW_domain,P46937,0.767379,NO,200,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-1.599,-2.787,1.188,5.37476,,,,,,1.9,,70.04,HPA,-1.484,0.153962,0.00300397,0.767379 kka2_1:4_P109L,kka2_1:4_109,Kka2,kka2_1:4,P00552,0.767476,NO,109,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.412,-3.58,2.168,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.168804,0.0070929,0.767476 Pab1_S155P,Pab1_155,Pab1,Pab1,P04147,0.767521,NO,155,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.039,-3.856,1.817,,,,,,,,,,PPB,-1.42267,0.175299,0.00208179,0.767521 beta-lactamase_N272S,beta-lactamase_272,TEM-1,beta-lactamase,P62593,0.767526,NO,272,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-1.127,-3.103,1.976,5.37826,0.081,H,A,0.09,-0.97,1.468,,63.64,BPB,-1.56333,0.221079,0.00545371,0.767526 beta-lactamase_0_T107V,beta-lactamase_0_107,TEM-1,beta-lactamase_0,P62593,0.767549,NO,107,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.117,-3.226,2.109,,,G,A,0.22,-0.06,3.73,,67.83,HPA,-1.265,0.0500837,0.00239347,0.767549 kka2_1:1_A247N,kka2_1:1_247,Kka2,kka2_1:1,P00552,0.767589,NO,247,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.459,-3.859,1.4,,1.01,S,A,0.46,0.65,7.731,7.731,92.05,HHH,-2.197,0.520039,0.0102428,0.767589 beta-lactamase_D161M,beta-lactamase_161,TEM-1,beta-lactamase,P62593,0.767723,NO,161,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.891,-4.899,4.008,5.12208,0.341,,A,0.23,-0.52,1.602,,61.19,HAB,-0.961333,0.221079,0.000897697,0.767723 beta-lactamase_E169P,beta-lactamase_169,TEM-1,beta-lactamase,P62593,0.767723,NO,169,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.23,-3.768,2.538,5.78896,0.337,,A,0.52,1,1.806,,73.08,PAH,-1.16533,0.221079,0.00400994,0.767723 kka2_1:8_G189V,kka2_1:8_189,Kka2,kka2_1:8,P00552,0.767806,NO,189,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.596,-3.782,3.186,,0.034,S,l,0.75,-0.99,,,,BOA,-0.739,0.100394,0.00253688,0.767806 kka2_1:8_G189V,kka2_1:8_189,Kka2,kka2_1:8,P00552,0.767806,NO,189,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.596,-3.782,3.186,,0.034,S,l,0.75,-0.99,,,,BOA,-0.739,0.100394,0.00253688,0.767806 kka2_1:4_R140M,kka2_1:4_140,Kka2,kka2_1:4,P00552,0.767813,NO,140,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.351,-4.639,3.288,,0.12,H,A,1.2,0.2,2.561,,53.03,BBH,-1.885,0.168804,0.00430167,0.767813 beta-lactamase_156_E119Y,beta-lactamase_156_119,TEM-1,beta-lactamase_156,P62593,0.767908,NO,119,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.412,-4.336,2.924,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.111618,0.00386966,0.767908 kka2_1:2_R18M,kka2_1:2_18,Kka2,kka2_1:2,P00552,0.767944,NO,18,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.055,-3.102,1.047,,0.474,T,A,1.2,0.54,8.405,8.405,71.59,ABH,-1.821,0.295029,0.00724065,0.767944 beta-lactamase_L89H,beta-lactamase_89,TEM-1,beta-lactamase,P62593,0.767956,NO,89,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.096,-4.892,3.796,5.41092,0.168,T,A,1.75,0.63,1.599,,64.34,PHO,-1.75767,0.221079,0.00207068,0.767956 beta-lactamase_39_D155P,beta-lactamase_39_155,TEM-1,beta-lactamase_39,P62593,0.767993,NO,155,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.889,-3.725,2.836,,0.049,,B,0.75,-0.9,3.208,,64.69,OAB,-1.62267,0.0495842,0.00135315,0.767993 beta-lactamase_0_K286F,beta-lactamase_0_286,TEM-1,beta-lactamase_0,P62593,0.767997,NO,286,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.0500837,,0.767997 beta-lactamase_0_L146F,beta-lactamase_0_146,TEM-1,beta-lactamase_0,P62593,0.768004,NO,146,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.462,-2.298,0.836,,0.007,H,A,0.55,-0.56,2.051,,64.69,AHP,-1.656,0.0500837,0.00474542,0.768004 beta-lactamase_0_A185V,beta-lactamase_0_185,TEM-1,beta-lactamase_0,P62593,0.768008,NO,185,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.406,-2.093,0.687,,,H,A,0.46,-1.02,1.203,,65.03,HHP,-1.84033,0.0500837,0.00467449,0.768008 beta-lactamase_0_A170H,beta-lactamase_0_170,TEM-1,beta-lactamase_0,P62593,0.768036,NO,170,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.237,-4.694,3.457,,0.126,,L,0.46,-0.35,2.427,,64.69,AHH,-1.63267,0.0500837,0.00431903,0.768036 kka2_1:1_A168Q,kka2_1:1_168,Kka2,kka2_1:1,P00552,0.76805,NO,168,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.989,-2.544,0.555,,0.67,H,A,0.46,0.15,25.546,25.546,64.39,OHA,-2.12933,0.520039,0.00806773,0.76805 beta-lactamase_T27N,beta-lactamase_27,TEM-1,beta-lactamase,P62593,0.768082,NO,27,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.905,-2.525,0.62,5.39752,0.007,H,A,0.69,-0.37,0.745,,93.01,APH,-1.97933,0.221079,0.00306559,0.768082 beta-lactamase_0_D174L,beta-lactamase_0_174,TEM-1,beta-lactamase_0,P62593,0.768118,NO,174,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.738,-3.808,3.07,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.0500837,0.00125633,0.768118 kka2_1:2_C31W,kka2_1:2_31,Kka2,kka2_1:2,P00552,0.768187,NO,31,C,W,CW,Special,Hydrophobic,5.07,5.89,0.82,215,121,204,83,108.5,227.8,119.3,-2.246,-5.453,3.207,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.295029,0.00681582,0.768187 kka2_1:8_G88C,kka2_1:8_88,Kka2,kka2_1:8,P00552,0.768205,NO,88,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.689,-5.252,3.563,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.100394,0.00685559,0.768205 kka2_1:8_G88C,kka2_1:8_88,Kka2,kka2_1:8,P00552,0.768205,NO,88,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.689,-5.252,3.563,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.100394,0.00685559,0.768205 kka2_1:2_D118V,kka2_1:2_118,Kka2,kka2_1:2,P00552,0.768277,NO,118,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.07,-3.108,1.038,,0.61,H,A,0.75,-0.05,2.237,,64.39,HAH,-1.32367,0.295029,0.0067852,0.768277 kka2_1:4_N58T,kka2_1:4_58,Kka2,kka2_1:4,P00552,0.768316,NO,58,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-2.641,-2.933,0.292,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.168804,0.00793425,0.768316 beta-lactamase_0_E175G,beta-lactamase_0_175,TEM-1,beta-lactamase_0,P62593,0.768329,NO,175,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.336,-3.483,1.147,,0.551,,A,1.04,1.05,2.334,,77.62,AAB,-1.31233,0.0500837,0.00482205,0.768329 beta-lactamase_2500_Y103H,beta-lactamase_2500_103,TEM-1,beta-lactamase_2500,P62593,0.768381,NO,103,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-1.33,-2.243,0.913,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.361275,0.00443048,0.768381 kka2_1:2_R239G,kka2_1:2_239,Kka2,kka2_1:2,P00552,0.768393,NO,239,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.949,-2.877,-0.072,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.295029,0.00835326,0.768393 kka2_1:4_T85L,kka2_1:4_85,Kka2,kka2_1:4,P00552,0.768399,NO,85,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.165,-2.782,0.617,,0.576,E,B,0.22,1.39,1.853,,71.59,HPA,-2.10133,0.168804,0.00634493,0.768399 kka2_1:1_W236L,kka2_1:1_236,Kka2,kka2_1:1,P00552,0.768452,NO,236,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-1.363,-2.199,0.836,,0.303,H,A,1.51,-0.76,12.263,12.263,48.48,AHH,-1.81267,0.520039,0.0088796,0.768452 kka2_1:8_M197F,kka2_1:8_197,Kka2,kka2_1:8,P00552,0.768505,NO,197,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.707,-3.862,2.155,,0.121,E,B,1.59,-1.19,4.408,,65.53,HHH,-1.847,0.100394,0.00921295,0.768505 kka2_1:8_M197F,kka2_1:8_197,Kka2,kka2_1:8,P00552,0.768505,NO,197,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.707,-3.862,2.155,,0.121,E,B,1.59,-1.19,4.408,,65.53,HHH,-1.847,0.100394,0.00921295,0.768505 Pab1_Y143E,Pab1_143,Pab1,Pab1,P04147,0.768538,NO,143,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-1.961,-3.351,1.39,,0.409,H,A,,0.3,,,,HHA,-1.39633,0.175299,0.00160364,0.768538 kka2_1:2_H106V,kka2_1:2_106,Kka2,kka2_1:2,P00552,0.768559,NO,106,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-3.13,-3.002,-0.128,,1.065,.,a,0.17,-0.95,2.53,,71.59,PBH,-2.10433,0.295029,0.00730778,0.768559 kka2_1:2_H188P,kka2_1:2_188,Kka2,kka2_1:2,P00552,0.768568,NO,188,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-0.913,-3.906,2.993,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.295029,0.00273139,0.768568 kka2_1:4_D127G,kka2_1:4_127,Kka2,kka2_1:4,P00552,0.7686,NO,127,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.364,-3.377,2.013,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.168804,0.00660501,0.7686 beta-lactamase_0_V31C,beta-lactamase_0_31,TEM-1,beta-lactamase_0,P62593,0.768615,NO,31,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.822,-3.252,1.43,,,H,A,0.44,-0.46,4.126,,73.78,BHB,-2.03767,0.0500837,0.00478065,0.768615 hsp90_E590N,hsp90_590,hsp90,hsp90,P02829,0.76867,NO,590,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.818,-3.051,0,4.65049,0.021,H,A,,0.03,,,,HAO,-3.338,0.368192,0.000222939,0.76867 beta-lactamase_0_R59D,beta-lactamase_0_59,TEM-1,beta-lactamase_0,P62593,0.768757,NO,59,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.345,-3.634,2.289,,0.329,S,L,1.2,-0.09,2.919,,73.08,HBO,-2.24267,0.0500837,0.00318082,0.768757 beta-lactamase_0_K32N,beta-lactamase_0_32,TEM-1,beta-lactamase_0,P62593,0.768836,NO,32,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.984,-2.965,0.981,,0.563,H,A,2.34,0.34,0.418,,73.08,HBA,-2.04233,0.0500837,0.00401283,0.768836 kka2_1:1_G181C,kka2_1:1_181,Kka2,kka2_1:1,P00552,0.768884,NO,181,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-2.698,-5.203,2.505,,0.379,S,B,0.75,0.78,15.356,15.356,71.59,AOA,-2.21,0.520039,0.00728319,0.768884 kka2_1:2_E169K,kka2_1:2_169,Kka2,kka2_1:2,P00552,0.768911,NO,169,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.996,-2.672,0.676,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.295029,0.00730086,0.768911 kka2_1:4_G88C,kka2_1:4_88,Kka2,kka2_1:4,P00552,0.768936,NO,88,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.689,-5.252,3.563,,0.54,S,l,0.29,1.51,7.899,,65.53,HOB,-1.718,0.168804,0.00685559,0.768936 beta-lactamase_H5W,beta-lactamase_5,TEM-1,beta-lactamase,P62593,0.768944,NO,5,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-2.698,-4.949,2.251,,,,,,,1.865,,72.73,PBH,-2.36967,0.221079,0.00292712,0.768944 beta-lactamase_0_D174W,beta-lactamase_0_174,TEM-1,beta-lactamase_0,P62593,0.768994,NO,174,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.738,-5.547,4.809,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.0500837,0.00125633,0.768994 gb1_G235P,gb1_235,gb1,gb1,P06654,0.769014,NO,235,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.419,-3.572,2.153,,,,,,,0.476,,11.83,POB,-1.86433,0.177985,0.00297491,0.769014 gb1_T237M,gb1_237,gb1,gb1,P06654,0.769014,NO,237,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.736,-4.496,2.76,,,,,,,0.218,,11.83,BPH,-2.27833,0.177985,0.00275316,0.769014 beta-lactamase_2500_W288F,beta-lactamase_2500_288,TEM-1,beta-lactamase_2500,P62593,0.76903,NO,288,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,,,,,,,,,,,,,BHO,,0.361275,,0.76903 beta-lactamase_H5S,beta-lactamase_5,TEM-1,beta-lactamase,P62593,0.769177,NO,5,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-2.698,-2.721,0.023,,,,,,,1.865,,72.73,PBH,-2.36967,0.221079,0.00292712,0.769177 kka2_1:1_G10C,kka2_1:1_10,Kka2,kka2_1:1,P00552,0.76922,NO,10,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.921,-5.151,3.23,,,,,,,1.862,,71.59,HOP,-2.10733,0.520039,0.00289233,0.76922 beta-lactamase_625_A247E,beta-lactamase_625_247,TEM-1,beta-lactamase_625,P62593,0.769265,NO,247,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.213352,0.00611275,0.769265 WW_domain_T198A,WW_domain_198,Yap65,WW_domain,P46937,0.76927,NO,198,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.451,-1.983,0.532,5.14348,,,,,,3.158,,70.04,PPH,-1.513,0.153962,0.00224534,0.76927 beta-lactamase_0_L55S,beta-lactamase_0_55,TEM-1,beta-lactamase_0,P62593,0.769341,NO,55,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.86,-3.706,1.846,,0.372,E,A,0.55,-0.36,1.967,,63.99,HHA,-2.247,0.0500837,0.00403741,0.769341 beta-lactamase_2500_A278E,beta-lactamase_2500_278,TEM-1,beta-lactamase_2500,P62593,0.769369,NO,278,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.361275,0.0310297,0.769369 PSD95pdz3_E373K,PSD95pdz3_373,PSD95pdz3,PSD95pdz3,P31016,0.769429,NO,373,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.404,-2.689,1.285,5.79743,,,,,27.9833,,,,BAP,-1.57667,0.0758425,0.000387698,0.769429 kka2_1:1_P167A,kka2_1:1_167,Kka2,kka2_1:1,P00552,0.769457,NO,167,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-2.403,-1.382,-1.021,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.520039,0.00543203,0.769457 kka2_1:2_P12T,kka2_1:2_12,Kka2,kka2_1:2,P00552,0.769482,NO,12,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.853,-3.419,2.566,,,.,B,0.52,1.25,0.261,,48.11,POH,-1.80767,0.295029,0.00500011,0.769482 beta-lactamase_0_A225Y,beta-lactamase_0_225,TEM-1,beta-lactamase_0,P62593,0.769495,NO,225,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.845,-4.327,2.482,,1,T,B,0.46,-0.38,11.722,11.722,74.48,OHO,-1.39967,0.0500837,0.00465057,0.769495 kka2_1:2_L170P,kka2_1:2_170,Kka2,kka2_1:2,P00552,0.769498,NO,170,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.28,-4.106,2.826,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.295029,0.00730791,0.769498 kka2_1:4_S40I,kka2_1:4_40,Kka2,kka2_1:4,P00552,0.76956,NO,40,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.645,-4.1,1.455,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.168804,0.00693477,0.76956 gb1_G240V,gb1_240,gb1,gb1,P06654,0.769689,NO,240,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.921,-3.489,2.568,,,,,,,,,,BOA,-1.87867,0.177985,0.00270792,0.769689 kka2_1:4_L170P,kka2_1:4_170,Kka2,kka2_1:4,P00552,0.769713,NO,170,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.28,-4.106,2.826,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.168804,0.00730791,0.769713 kka2_1:4_N200M,kka2_1:4_200,Kka2,kka2_1:4,P00552,0.769714,NO,200,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-2.446,-4.957,2.511,,0.756,T,L,0.61,-0.08,1.746,,64.39,APO,-2.08,0.168804,0.00838549,0.769714 beta-lactamase_0_D48C,beta-lactamase_0_48,TEM-1,beta-lactamase_0,P62593,0.769718,NO,48,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.101,-5.125,4.024,,0.189,E,B,0.75,0.21,17.825,17.825,50.35,HAH,-1.62467,0.0500837,0.0027273,0.769718 beta-lactamase_R162E,beta-lactamase_162,TEM-1,beta-lactamase,P62593,0.769725,NO,162,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.016,-3.337,2.321,5.34456,0.124,S,B,0.68,-0.37,31.656,31.656,64.69,ABH,-1.25,0.221079,0.000561334,0.769725 kka2_1:8_A144T,kka2_1:8_144,Kka2,kka2_1:8,P00552,0.769733,NO,144,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.859,-3.269,2.41,,,H,A,1.04,0.21,1.118,,52.65,BHB,-1.72933,0.100394,0.00231095,0.769733 kka2_1:8_A144T,kka2_1:8_144,Kka2,kka2_1:8,P00552,0.769733,NO,144,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.859,-3.269,2.41,,,H,A,1.04,0.21,1.118,,52.65,BHB,-1.72933,0.100394,0.00231095,0.769733 beta-lactamase_0_L150P,beta-lactamase_0_150,TEM-1,beta-lactamase_0,P62593,0.770069,NO,150,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.326,-4.037,2.711,,,H,A,0.55,-0.2,2.128,,62.94,HHB,-1.86167,0.0500837,0.00463171,0.770069 kka2_1:8_L243P,kka2_1:8_243,Kka2,kka2_1:8,P00552,0.770097,NO,243,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-2.651,-4.123,1.472,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.100394,0.00884927,0.770097 kka2_1:8_L243P,kka2_1:8_243,Kka2,kka2_1:8,P00552,0.770097,NO,243,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-2.651,-4.123,1.472,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.100394,0.00884927,0.770097 hsp90_G584Q,hsp90_584,hsp90,hsp90,P02829,0.770201,NO,584,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-2.511,-3.278,0,5.20094,0.414,S,b,0.84,0.33,,,,HOH,-3.32733,0.368192,0.000222939,0.770201 kka2_1:2_L57P,kka2_1:2_57,Kka2,kka2_1:2,P00552,0.770241,NO,57,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.898,-3.173,1.275,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.295029,0.00723769,0.770241 kka2_1:2_C77A,kka2_1:2_77,Kka2,kka2_1:2,P00552,0.770258,NO,77,C,A,CA,Special,Hydrophobic,5.07,6,0.93,195,121,89,-32,108.5,88.6,-19.9,-1.477,-1.773,0.296,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.295029,0.00441216,0.770258 beta-lactamase_0_N130I,beta-lactamase_0_130,TEM-1,beta-lactamase_0,P62593,0.770284,NO,130,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-0.798,-4.01,3.212,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.0500837,0.000683376,0.770284 kka2_1:1_L94R,kka2_1:1_94,Kka2,kka2_1:1,P00552,0.770285,NO,94,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.618,-3.994,2.376,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.520039,0.00520888,0.770285 kka2_1:2_G201N,kka2_1:2_201,Kka2,kka2_1:2,P00552,0.770292,NO,201,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.56,-2.642,1.082,,0.149,T,l,0.29,-0.57,16.092,16.092,52.65,POB,-1.92233,0.295029,0.00820117,0.770292 beta-lactamase_T187H,beta-lactamase_187,TEM-1,beta-lactamase,P62593,0.770309,NO,187,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.401,-4.688,3.287,5.11453,0.007,H,A,0.3,-1.19,1.751,,67.48,PPH,-1.69633,0.221079,0.00491782,0.770309 beta-lactamase_0_T186L,beta-lactamase_0_186,TEM-1,beta-lactamase_0,P62593,0.770361,NO,186,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.522,-2.882,0.36,,0.396,H,A,0.22,-0.28,16.606,16.606,77.62,HPP,-1.77633,0.0500837,0.00485034,0.770361 gb1_Y271H,gb1_271,gb1,gb1,P06654,0.770361,NO,271,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-1.181,-3.557,2.376,,,,,,,,,,PHA,-1.92933,0.177985,0.00236544,0.770361 kka2_1:1_A9E,kka2_1:1_9,Kka2,kka2_1:1,P00552,0.770537,NO,9,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.079,-3.534,1.455,,,,,,,0.383,,71.59,BHO,-2.253,0.520039,0.00273264,0.770537 beta-lactamase_625_D99P,beta-lactamase_625_99,TEM-1,beta-lactamase_625,P62593,0.770565,NO,99,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.191,-3.8,2.609,,0.402,G,A,0.75,0.36,1.318,,64.69,PAH,-1.794,0.213352,0.00305446,0.770565 beta-lactamase_0_V72N,beta-lactamase_0_72,TEM-1,beta-lactamase_0,P62593,0.770605,NO,72,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.658,-4.143,2.485,,,H,A,0.44,-1.03,2.964,,65.73,BHH,-1.32167,0.0500837,0.00501194,0.770605 kka2_1:4_L152E,kka2_1:4_152,Kka2,kka2_1:4,P00552,0.770636,NO,152,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.521,-3.005,1.484,,0.547,,A,1.59,1.36,2.318,,63.64,OHH,-1.162,0.168804,0.00674868,0.770636 beta-lactamase_0_R176H,beta-lactamase_0_176,TEM-1,beta-lactamase_0,P62593,0.770652,NO,176,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-0.863,-4.23,3.367,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.0500837,0.00105554,0.770652 beta-lactamase_2500_E195V,beta-lactamase_2500_195,TEM-1,beta-lactamase_2500,P62593,0.770681,NO,195,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.186,-3.798,1.612,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.361275,0.00496565,0.770681 PSD95pdz3_L353N,PSD95pdz3_353,PSD95pdz3,PSD95pdz3,P31016,0.770737,NO,353,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.347,-3.805,2.458,5.81136,,,,,17.3525,,,,AHB,-1.50533,0.0758425,0.000664742,0.770737 kka2_1:4_R89G,kka2_1:4_89,Kka2,kka2_1:4,P00552,0.770843,NO,89,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.548,-2.87,1.322,,0.209,E,B,1.2,1.41,4.412,,64.39,OBA,-1.89867,0.168804,0.00524373,0.770843 beta-lactamase_0_G52I,beta-lactamase_0_52,TEM-1,beta-lactamase_0,P62593,0.770857,NO,52,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.149,-4.163,3.014,,0.299,,l,0.29,-0.04,1.164,,64.69,POB,-1.66267,0.0500837,0.00340138,0.770857 beta-lactamase_0_D207W,beta-lactamase_0_207,TEM-1,beta-lactamase_0,P62593,0.770908,NO,207,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.064,-5.493,3.429,,0.409,H,A,0.75,0.12,5.277,,77.62,HAH,-1.77033,0.0500837,0.00592942,0.770908 beta-lactamase_C121G,beta-lactamase_121,TEM-1,beta-lactamase,P62593,0.770914,NO,121,C,G,CG,Special,Special,5.07,3.29388,-1.77612,159,121,75,-46,108.5,60.1,-48.4,-0.953,-3.581,2.628,5.12205,,H,A,2.8,-0.81,7.644,,63.29,HOP,-1.46767,0.221079,0.000744322,0.770914 beta-lactamase_0_A235Y,beta-lactamase_0_235,TEM-1,beta-lactamase_0,P62593,0.771016,NO,235,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.266,-4.294,3.028,,0.32,E,B,0.46,-0.86,2.261,,50,OHO,-0.89,0.0500837,0.00493474,0.771016 kka2_1:2_A35D,kka2_1:2_35,Kka2,kka2_1:2,P00552,0.771028,NO,35,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.127,-2.127,0,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.295029,0.00630016,0.771028 gb1_G240T,gb1_240,gb1,gb1,P06654,0.77103,NO,240,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.921,-3.382,2.461,,,,,,,,,,BOA,-1.87867,0.177985,0.00270792,0.77103 beta-lactamase_0_K53H,beta-lactamase_0_53,TEM-1,beta-lactamase_0,P62593,0.771061,NO,53,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-2.313,-4.67,2.357,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.0500837,0.00383383,0.771061 beta-lactamase_E46G,beta-lactamase_46,TEM-1,beta-lactamase,P62593,0.771179,NO,46,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.94,-2.778,0.838,5.36461,0.021,E,B,1.51,0.14,0.373,,59.44,HAH,-2.079,0.221079,0.00427568,0.771179 beta-lactamase_156_L223P,beta-lactamase_156_223,TEM-1,beta-lactamase_156,P62593,0.771197,NO,223,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.055,-4.101,3.046,,0.27,,B,0.55,0.09,1.511,,74.48,HHO,-1.35033,0.111618,0.00372793,0.771197 beta-lactamase_F70L,beta-lactamase_70,TEM-1,beta-lactamase,P62593,0.771245,NO,70,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.169,-2.96,1.791,5.42055,,H,A,1.1,-1.34,1.14,,63.99,PHB,-0.980667,0.221079,0.00193499,0.771245 beta-lactamase_0_N173F,beta-lactamase_0_173,TEM-1,beta-lactamase_0,P62593,0.771302,NO,173,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-2.663,-4.355,1.692,,1.044,T,l,0.61,1.25,1.133,,77.62,OPA,-1.46633,0.0500837,0.0033769,0.771302 kka2_1:1_A65E,kka2_1:1_65,Kka2,kka2_1:1,P00552,0.771457,NO,65,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.744,-2.135,0.391,,0.437,H,A,0.46,-0.39,3.012,,63.64,HHB,-1.38733,0.520039,0.00709258,0.771457 beta-lactamase_0_A185F,beta-lactamase_0_185,TEM-1,beta-lactamase_0,P62593,0.771631,NO,185,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.406,-4.091,2.685,,,H,A,0.46,-1.02,1.203,,65.03,HHP,-1.84033,0.0500837,0.00467449,0.771631 kka2_1:2_D157H,kka2_1:2_157,Kka2,kka2_1:2,P00552,0.771657,NO,157,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.993,-4.51,3.517,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.295029,0.0042313,0.771657 kka2_1:2_I246R,kka2_1:2_246,Kka2,kka2_1:2,P00552,0.77167,NO,246,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-2.008,-3.32,1.312,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.295029,0.0139479,0.77167 beta-lactamase_F6D,beta-lactamase_6,TEM-1,beta-lactamase,P62593,0.771706,NO,6,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.847,-3.877,2.03,,,,,,,1.276,,67.83,BHB,-2.076,0.221079,0.00261627,0.771706 beta-lactamase_S51C,beta-lactamase_51,TEM-1,beta-lactamase,P62593,0.771706,NO,51,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.526,-4.878,3.352,5.06164,0.496,T,A,0.25,0.26,1.699,,72.73,PPO,-1.88467,0.221079,0.00504821,0.771706 beta-lactamase_39_T158Q,beta-lactamase_39_158,TEM-1,beta-lactamase_39,P62593,0.771719,NO,158,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.116,-3.908,2.792,,0.036,,B,0.22,-0.85,2.755,,69.58,HPB,-1.269,0.0495842,0.00341825,0.771719 beta-lactamase_2500_P165N,beta-lactamase_2500_165,TEM-1,beta-lactamase_2500,P62593,0.77181,NO,165,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.373,-3.703,2.33,,0.203,T,A,0.52,-0.31,0.414,,73.78,AOA,-1.359,0.361275,0.00549538,0.77181 beta-lactamase_39_L150D,beta-lactamase_39_150,TEM-1,beta-lactamase_39,P62593,0.77183,NO,150,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.326,-4.043,2.717,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.0495842,0.00463171,0.77183 kka2_1:8_R140H,kka2_1:8_140,Kka2,kka2_1:8,P00552,0.771846,NO,140,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.351,-4.514,3.163,,0.12,H,A,0.16,0.2,2.874,,53.03,BBH,-1.885,0.100394,0.00430167,0.771846 kka2_1:8_R140H,kka2_1:8_140,Kka2,kka2_1:8,P00552,0.771846,NO,140,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.351,-4.514,3.163,,0.12,H,A,0.16,0.2,2.874,,53.03,BBH,-1.885,0.100394,0.00430167,0.771846 beta-lactamase_0_R176I,beta-lactamase_0_176,TEM-1,beta-lactamase_0,P62593,0.771879,NO,176,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-0.863,-4.01,3.147,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.0500837,0.00105554,0.771879 beta-lactamase_2500_Q204F,beta-lactamase_2500_204,TEM-1,beta-lactamase_2500,P62593,0.771918,NO,204,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-1.382,-4.303,2.921,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.361275,0.00364106,0.771918 PSD95pdz3_I359T,PSD95pdz3_359,PSD95pdz3,PSD95pdz3,P31016,0.771934,NO,359,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.63,-3.103,1.473,5.35151,,,,,14.8012,,,,PHH,-1.58667,0.0758425,0.000580694,0.771934 beta-lactamase_2500_T264R,beta-lactamase_2500_264,TEM-1,beta-lactamase_2500,P62593,0.771946,NO,264,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.361275,0.0119399,0.771946 kka2_1:2_G10I,kka2_1:2_10,Kka2,kka2_1:2,P00552,0.771982,NO,10,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.921,-4.096,2.175,,,,,,,2.192,,71.59,HOP,-2.10733,0.295029,0.00289233,0.771982 kka2_1:4_A224T,kka2_1:4_224,Kka2,kka2_1:4,P00552,0.771992,NO,224,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.977,-1.898,0.921,,,H,A,0.46,-1.26,0.93,,63.64,HHP,-1.41033,0.168804,0.00352047,0.771992 kka2_1:1_D33N,kka2_1:1_33,Kka2,kka2_1:1,P00552,0.772078,NO,33,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.186,-2.693,0.507,,0.561,S,A,0.75,3.35,2.568,,71.59,PAH,-1.306,0.520039,0.00633568,0.772078 beta-lactamase_N134Q,beta-lactamase_134,TEM-1,beta-lactamase,P62593,0.772146,NO,134,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-0.879,-3.672,2.793,5.07245,0.138,H,A,0.09,-0.6,1.441,,53.15,HPH,-1.02233,0.221079,0.000644786,0.772146 beta-lactamase_0_R63G,beta-lactamase_0_63,TEM-1,beta-lactamase_0,P62593,0.772164,NO,63,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-0.943,-3.426,2.483,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.0500837,0.00126938,0.772164 kka2_1:1_S54I,kka2_1:1_54,Kka2,kka2_1:1,P00552,0.772179,NO,54,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.471,-2.562,0.091,,0.408,S,b,0.27,1.01,6.085,,71.59,HPO,-2.259,0.520039,0.00782867,0.772179 beta-lactamase_L146C,beta-lactamase_146,TEM-1,beta-lactamase,P62593,0.772242,NO,146,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.462,-4.847,3.385,5.62483,0.007,H,A,1.3,-0.56,1.953,,64.69,AHP,-1.656,0.221079,0.00474542,0.772242 beta-lactamase_39_S104E,beta-lactamase_39_104,TEM-1,beta-lactamase_39,P62593,0.772261,NO,104,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.015,-3.366,2.351,,0.04,,b,0.27,0.57,4.02,,63.29,HPO,-1.05267,0.0495842,0.00218083,0.772261 beta-lactamase_L218I,beta-lactamase_218,TEM-1,beta-lactamase,P62593,0.77228,NO,218,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.391,-3.447,2.056,4.88972,,I,b,2.89,-0.53,12.788,12.788,74.48,OHH,-1.58867,0.221079,0.00618274,0.77228 beta-lactamase_0_G249N,beta-lactamase_0_249,TEM-1,beta-lactamase_0,P62593,0.772286,NO,249,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.0500837,0.00220169,0.772286 kka2_1:1_G181S,kka2_1:1_181,Kka2,kka2_1:1,P00552,0.7723,NO,181,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-2.698,-2.485,-0.213,,0.379,S,B,0.75,0.78,15.356,15.356,71.59,AOA,-2.21,0.520039,0.00728319,0.7723 beta-lactamase_0_S221W,beta-lactamase_0_221,TEM-1,beta-lactamase_0,P62593,0.772307,NO,221,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.754,-5.418,3.664,,0.624,H,A,0.27,-0.2,2.914,,74.48,BPH,-1.59967,0.0500837,0.0046094,0.772307 beta-lactamase_T187Q,beta-lactamase_187,TEM-1,beta-lactamase,P62593,0.772312,NO,187,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.401,-4.004,2.603,5.11453,0.007,H,A,0.3,-1.19,1.751,,67.48,PPH,-1.69633,0.221079,0.00491782,0.772312 kka2_1:2_L232M,kka2_1:2_232,Kka2,kka2_1:2,P00552,0.772325,NO,232,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.514,-4.338,2.824,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.295029,0.00800103,0.772325 Pab1_D138F,Pab1_138,Pab1,Pab1,P04147,0.772329,NO,138,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.128,-4.162,3.034,,0.427,,B,,-0.03,,,,HAP,-1.13967,0.175299,0.000567877,0.772329 gb1_A246F,gb1_246,gb1,gb1,P06654,0.77236,NO,246,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.175,-3.803,2.628,,,,,,,,,,AHH,-1.87033,0.177985,0.00190625,0.77236 gb1_Q258W,gb1_258,gb1,gb1,P06654,0.77236,NO,258,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.095,-5.257,3.162,,,,,,,0.86,,37.28,BPH,-1.88333,0.177985,0.00437595,0.77236 kka2_1:4_D208A,kka2_1:4_208,Kka2,kka2_1:4,P00552,0.772393,NO,208,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.708,-3.331,2.623,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.168804,0.00212588,0.772393 kka2_1:2_D156V,kka2_1:2_156,Kka2,kka2_1:2,P00552,0.772504,NO,156,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.696,-3.632,1.936,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.295029,0.00926998,0.772504 kka2_1:4_F37V,kka2_1:4_37,Kka2,kka2_1:4,P00552,0.772608,NO,37,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.427,-2.858,1.431,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.168804,0.00586193,0.772608 kka2_1:8_G95V,kka2_1:8_95,Kka2,kka2_1:8,P00552,0.772668,NO,95,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-2.403,-2.997,0.594,,0.126,E,B,0.75,-0.74,7.774,,71.59,HOA,-2.198,0.100394,0.00743616,0.772668 kka2_1:8_G95V,kka2_1:8_95,Kka2,kka2_1:8,P00552,0.772668,NO,95,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-2.403,-2.997,0.594,,0.126,E,B,0.75,-0.74,7.774,,71.59,HOA,-2.198,0.100394,0.00743616,0.772668 kka2_1:1_I228Q,kka2_1:1_228,Kka2,kka2_1:1,P00552,0.77272,NO,228,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.142,-4.362,3.22,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.520039,0.00458834,0.77272 WW_domain_S184H,WW_domain_184,Yap65,WW_domain,P46937,0.772803,NO,184,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.363,-4.354,2.991,5.06696,,,,,,,,,PPO,-1.39133,0.153962,0.00231095,0.772803 beta-lactamase_2500_M127N,beta-lactamase_2500_127,TEM-1,beta-lactamase_2500,P62593,0.772841,NO,127,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-2.251,-4.047,1.796,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.361275,0.00437927,0.772841 kka2_1:1_E149Q,kka2_1:1_149,Kka2,kka2_1:1,P00552,0.772865,NO,149,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.994,-2.493,0.499,,0.674,H,A,1.04,1.63,3.671,,71.59,HAH,-1.59667,0.520039,0.00803343,0.772865 beta-lactamase_2500_T116D,beta-lactamase_2500_116,TEM-1,beta-lactamase_2500,P62593,0.772925,NO,116,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.28,-3.524,2.244,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.361275,0.00336175,0.772925 kka2_1:1_S32V,kka2_1:1_32,Kka2,kka2_1:1,P00552,0.772933,NO,32,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-0.804,-3.557,2.753,,0.768,S,b,0.27,3.75,,,,OPA,-1.74533,0.520039,0.00149998,0.772933 beta-lactamase_156_V31F,beta-lactamase_156_31,TEM-1,beta-lactamase_156,P62593,0.772937,NO,31,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.822,-2.736,0.914,,,H,A,0.44,-0.46,4.126,,73.78,BHB,-2.03767,0.111618,0.00478065,0.772937 gb1_E282H,gb1_282,gb1,gb1,P06654,0.773021,NO,282,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.318,-4.129,2.811,,,,,,,1.075,,35.71,PAO,-1.573,0.177985,0.00209643,0.773021 beta-lactamase_0_I54G,beta-lactamase_0_54,TEM-1,beta-lactamase_0,P62593,0.773026,NO,54,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-2.838,-3.612,0.774,,0.669,E,B,0.48,-0.14,0.541,,73.78,BHH,-2.337,0.0500837,0.00403589,0.773026 kka2_1:1_A255E,kka2_1:1_255,Kka2,kka2_1:1,P00552,0.77303,NO,255,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.715,-2.621,0.906,,0.466,H,A,0.46,-0.52,0.946,,65.53,HHH,-1.71267,0.520039,0.0126809,0.77303 kka2_1:1_L53V,kka2_1:1_53,Kka2,kka2_1:1,P00552,0.773231,NO,53,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-2.681,-2.592,-0.089,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.520039,0.00671168,0.773231 Pab1_Q194P,Pab1_194,Pab1,Pab1,P04147,0.773252,NO,194,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.179,-3.888,1.709,,,,,,,,,,OPA,-1.59767,0.175299,0.0016145,0.773252 kka2_1:4_A117Q,kka2_1:4_117,Kka2,kka2_1:4,P00552,0.773279,NO,117,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.828,-3.991,3.163,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.168804,0.00282984,0.773279 beta-lactamase_0_K53Q,beta-lactamase_0_53,TEM-1,beta-lactamase_0,P62593,0.773288,NO,53,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-2.313,-2.642,0.329,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.0500837,0.00383383,0.773288 Pab1_I137A,Pab1_137,Pab1,Pab1,P04147,0.7733,NO,137,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.212,-2.895,1.683,,0.068,,B,0.77,0.35,,,,AHA,-1.314,0.175299,0.000342224,0.7733 kka2_1:4_A229S,kka2_1:4_229,Kka2,kka2_1:4,P00552,0.773363,NO,229,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.739,-3.404,1.665,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.168804,0.00942138,0.773363 kka2_1:4_A34S,kka2_1:4_34,Kka2,kka2_1:4,P00552,0.773363,NO,34,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.928,-1.892,0.964,,0.417,.,B,0.46,2.29,0.262,,52.27,AHH,-1.747,0.168804,0.00343484,0.773363 beta-lactamase_156_G236H,beta-lactamase_156_236,TEM-1,beta-lactamase_156,P62593,0.773398,NO,236,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.784,-4.704,3.92,,0.241,,b,0.29,-0.59,1.883,,64.69,HOO,-1.025,0.111618,0.00162372,0.773398 beta-lactamase_2500_G216L,beta-lactamase_2500_216,TEM-1,beta-lactamase_2500,P62593,0.773428,NO,216,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.477,-3.78,2.303,,0.437,I,A,0.29,-0.58,1.983,,74.48,HOO,-1.68067,0.361275,0.00639568,0.773428 beta-lactamase_2500_T27L,beta-lactamase_2500_27,TEM-1,beta-lactamase_2500,P62593,0.77344,NO,27,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.905,-2.65,0.745,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.361275,0.00306559,0.77344 kka2_1:1_R18P,kka2_1:1_18,Kka2,kka2_1:1,P00552,0.77345,NO,18,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.055,-4.134,2.079,,0.474,T,A,1.2,0.54,11.422,11.422,71.59,ABH,-1.821,0.520039,0.00724065,0.77345 kka2_1:8_W69L,kka2_1:8_69,Kka2,kka2_1:8,P00552,0.773455,NO,69,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-0.859,-3.385,2.526,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.100394,0.0012874,0.773455 kka2_1:8_W69L,kka2_1:8_69,Kka2,kka2_1:8,P00552,0.773455,NO,69,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-0.859,-3.385,2.526,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.100394,0.0012874,0.773455 kka2_1:1_A117Q,kka2_1:1_117,Kka2,kka2_1:1,P00552,0.773466,NO,117,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.828,-3.991,3.163,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.520039,0.00282984,0.773466 kka2_1:8_W91C,kka2_1:8_91,Kka2,kka2_1:8,P00552,0.773488,NO,91,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-1.178,-5.004,3.826,,0.077,E,B,1.51,0.27,2.51,,48.48,AHH,-1.51,0.100394,0.00358653,0.773488 kka2_1:8_W91C,kka2_1:8_91,Kka2,kka2_1:8,P00552,0.773488,NO,91,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-1.178,-5.004,3.826,,0.077,E,B,1.51,0.27,2.51,,48.48,AHH,-1.51,0.100394,0.00358653,0.773488 kka2_1:4_M116K,kka2_1:4_116,Kka2,kka2_1:4,P00552,0.773504,NO,116,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-2.482,-3.871,1.389,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.168804,0.00745147,0.773504 beta-lactamase_0_D207Q,beta-lactamase_0_207,TEM-1,beta-lactamase_0,P62593,0.77357,NO,207,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.064,-2.209,0.145,,0.409,H,A,0.75,0.12,5.277,,77.62,HAH,-1.77033,0.0500837,0.00592942,0.77357 beta-lactamase_625_D212R,beta-lactamase_625_212,TEM-1,beta-lactamase_625,P62593,0.773572,NO,212,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.624,-3.921,2.297,,0.037,,b,0.75,-0.58,1.516,,74.48,HAB,-1.77667,0.213352,0.00644302,0.773572 PSD95pdz3_V365P,PSD95pdz3_365,PSD95pdz3,PSD95pdz3,P31016,0.773579,NO,365,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.592,-3.56,1.968,5.03791,,,,,18.9657,2.364,,81.35,OHA,-1.288,0.0758425,0.000649764,0.773579 kka2_1:1_L212M,kka2_1:1_212,Kka2,kka2_1:1,P00552,0.773641,NO,212,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.904,-3.974,3.07,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.520039,0.0031426,0.773641 beta-lactamase_0_L111H,beta-lactamase_0_111,TEM-1,beta-lactamase_0,P62593,0.773665,NO,111,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.76,-4.922,3.162,,0.328,T,A,0.55,0.93,1.966,,64.34,BHP,-1.884,0.0500837,0.00480671,0.773665 gb1_G235R,gb1_235,gb1,gb1,P06654,0.773679,NO,235,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.419,-3.625,2.206,,,,,,,0.476,,11.83,POB,-1.86433,0.177985,0.00297491,0.773679 kka2_1:1_R143L,kka2_1:1_143,Kka2,kka2_1:1,P00552,0.773702,NO,143,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.525,-2.21,-0.315,,0.325,H,A,0.16,1.22,3.6,,65.53,ABH,-1.86833,0.520039,0.00662247,0.773702 Pab1_S155E,Pab1_155,Pab1,Pab1,P04147,0.773775,NO,155,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.039,-3.646,1.607,,,,,,,,,,PPB,-1.42267,0.175299,0.00208179,0.773775 beta-lactamase_156_G281H,beta-lactamase_156_281,TEM-1,beta-lactamase_156,P62593,0.773795,NO,281,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.111618,0.0406482,0.773795 beta-lactamase_F13Q,beta-lactamase_13,TEM-1,beta-lactamase,P62593,0.773831,NO,13,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-2.394,-4.071,1.677,,,,,,,4.079,,77.62,OHH,-2.382,0.221079,0.0029078,0.773831 beta-lactamase_G114H,beta-lactamase_114,TEM-1,beta-lactamase,P62593,0.773831,NO,114,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.094,-4.665,3.571,4.92659,0.011,,p,0.77,0.35,2.148,,41.61,AOH,-1.43733,0.221079,0.00224919,0.773831 beta-lactamase_G114N,beta-lactamase_114,TEM-1,beta-lactamase,P62593,0.773831,NO,114,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.094,-2.731,1.637,4.92659,0.011,,p,0.77,0.35,2.148,,41.61,AOH,-1.43733,0.221079,0.00224919,0.773831 beta-lactamase_G141C,beta-lactamase_141,TEM-1,beta-lactamase,P62593,0.773831,NO,141,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.828,-5.167,4.339,5.03155,0.575,T,l,0.76,-0.28,0.198,,64.69,HOO,-1.08933,0.221079,0.0012419,0.773831 beta-lactamase_G263T,beta-lactamase_263,TEM-1,beta-lactamase,P62593,0.773831,NO,263,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-2.031,-3.618,1.587,5.09799,0.517,S,l,0.77,0.31,16.425,16.425,77.62,POP,-1.78267,0.221079,0.0110582,0.773831 beta-lactamase_G52T,beta-lactamase_52,TEM-1,beta-lactamase,P62593,0.773831,NO,52,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.149,-3.586,2.437,5.12093,0.299,,l,0.77,-0.04,2.103,,64.69,POB,-1.66267,0.221079,0.00340138,0.773831 beta-lactamase_K30Y,beta-lactamase_30,TEM-1,beta-lactamase,P62593,0.773831,NO,30,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-2.307,-4.255,1.948,5.30605,0.142,H,A,1.82,-0.65,2.434,,93.01,HBH,-2.32833,0.221079,0.00448593,0.773831 beta-lactamase_L100Q,beta-lactamase_100,TEM-1,beta-lactamase,P62593,0.773831,NO,100,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.218,-4.259,3.041,5.60291,0.343,,B,1.3,0.13,1.173,,63.29,AHH,-1.23467,0.221079,0.00413885,0.773831 beta-lactamase_P20G,beta-lactamase_20,TEM-1,beta-lactamase,P62593,0.773831,NO,20,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.74,-3.229,1.489,,,,,,,0.368,,67.83,HOH,-1.765,0.221079,0.00235322,0.773831 beta-lactamase_R7M,beta-lactamase_7,TEM-1,beta-lactamase,P62593,0.773831,NO,7,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.683,-4.3,2.617,,,,,,,2.44,,67.13,HBH,-1.96267,0.221079,0.00211375,0.773831 beta-lactamase_S264K,beta-lactamase_264,TEM-1,beta-lactamase,P62593,0.773831,NO,264,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.985,-3.583,1.598,4.67475,0.04,,B,0.25,0.29,34.251,34.251,73.78,OPP,-2.19867,0.221079,0.0119399,0.773831 beta-lactamase_0_V42R,beta-lactamase_0_42,TEM-1,beta-lactamase_0,P62593,0.773873,NO,42,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.564,-4.138,2.574,,0.017,E,B,0.44,-0.51,1.659,,63.99,BHO,-1.042,0.0500837,0.00404515,0.773873 kka2_1:2_Y218C,kka2_1:2_218,Kka2,kka2_1:2,P00552,0.773929,NO,218,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-1.438,-2.974,1.536,,0.122,H,A,0.21,-0.69,1.022,,56.06,BHP,-1.17533,0.295029,0.0126098,0.773929 beta-lactamase_0_H287D,beta-lactamase_0_287,TEM-1,beta-lactamase_0,P62593,0.773937,NO,287,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,,,,,,,,,,,,,BBH,-1.111,0.0500837,,0.773937 kka2_1:2_I246T,kka2_1:2_246,Kka2,kka2_1:2,P00552,0.774013,NO,246,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-2.008,-3.038,1.03,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.295029,0.0139479,0.774013 kka2_1:2_L107I,kka2_1:2_107,Kka2,kka2_1:2,P00552,0.774028,NO,107,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.238,-2.172,0.934,,0.197,,B,1.59,-1.1,2.68,,71.59,BHH,-2.143,0.295029,0.00561937,0.774028 kka2_1:8_R143I,kka2_1:8_143,Kka2,kka2_1:8,P00552,0.774119,NO,143,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.525,-2.77,0.245,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.100394,0.00662247,0.774119 kka2_1:8_R143I,kka2_1:8_143,Kka2,kka2_1:8,P00552,0.774119,NO,143,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.525,-2.77,0.245,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.100394,0.00662247,0.774119 kka2_1:2_P76L,kka2_1:2_76,Kka2,kka2_1:2,P00552,0.774188,NO,76,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.449,-2.705,1.256,,0.331,.,B,0.52,-0.41,0.345,,63.64,HOO,-1.662,0.295029,0.00625685,0.774188 Ubiquitin_D32R,Ubiquitin_32,Uba1,Ubiquitin,P0CG48,0.774194,NO,32,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.451,-3.793,2.342,4.96502,0.835,H,A,,1.4,,,,PAB,-1.47067,0.205827,0.000758819,0.774194 Ubiquitin_I30T,Ubiquitin_30,Uba1,Ubiquitin,P0CG48,0.774194,NO,30,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.205,-3.358,2.153,4.80264,,H,A,,-0.51,,,,BHP,-1.45133,0.205827,0.000720128,0.774194 Ubiquitin_T66A,Ubiquitin_66,Uba1,Ubiquitin,P0CG48,0.774194,NO,66,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.58,-2.583,1.003,5.02702,0.46,E,B,0.8,-0.81,28.36,28.36,39.71,PPH,-1.51667,0.205827,0.000598414,0.774194 kka2_1:4_P45L,kka2_1:4_45,Kka2,kka2_1:4,P00552,0.774258,NO,45,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.774,-3.048,1.274,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.168804,0.00590481,0.774258 gb1_G240E,gb1_240,gb1,gb1,P06654,0.774334,NO,240,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.921,-3.4,2.479,,,,,,,,,,BOA,-1.87867,0.177985,0.00270792,0.774334 beta-lactamase_0_L49G,beta-lactamase_0_49,TEM-1,beta-lactamase_0,P62593,0.774346,NO,49,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.897,-3.581,1.684,,0.131,T,A,0.55,0.04,13.838,13.838,64.69,AHP,-1.99233,0.0500837,0.00401477,0.774346 beta-lactamase_0_G253L,beta-lactamase_0_253,TEM-1,beta-lactamase_0,P62593,0.774348,NO,253,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.0500837,0.00786358,0.774348 beta-lactamase_625_G52W,beta-lactamase_625_52,TEM-1,beta-lactamase_625,P62593,0.774369,NO,52,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.149,-5.364,4.215,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.213352,0.00340138,0.774369 kka2_1:1_S104R,kka2_1:1_104,Kka2,kka2_1:1,P00552,0.774375,NO,104,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.436,-3.063,1.627,,0.536,T,A,0.27,-1.11,5.49,,63.64,HPP,-1.91433,0.520039,0.00555207,0.774375 kka2_1:4_Q27P,kka2_1:4_27,Kka2,kka2_1:4,P00552,0.774382,NO,27,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-1.659,-3,1.341,,0.608,,A,0.4,0.71,1.498,,65.53,PPP,-1.90733,0.168804,0.00595365,0.774382 kka2_1:8_W24D,kka2_1:8_24,Kka2,kka2_1:8,P00552,0.774404,NO,24,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-1.779,-4.166,2.387,,0.477,E,B,1.51,-0.21,2.503,,56.06,AHH,-2.24467,0.100394,0.00631564,0.774404 kka2_1:8_W24D,kka2_1:8_24,Kka2,kka2_1:8,P00552,0.774404,NO,24,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-1.779,-4.166,2.387,,0.477,E,B,1.51,-0.21,2.503,,56.06,AHH,-2.24467,0.100394,0.00631564,0.774404 beta-lactamase_0_G154P,beta-lactamase_0_154,TEM-1,beta-lactamase_0,P62593,0.774459,NO,154,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.823,-3.881,3.058,,0.54,T,l,0.29,-0.56,3.629,,64.69,HOA,-1.635,0.0500837,0.00180205,0.774459 Pab1_F149H,Pab1_149,Pab1,Pab1,P04147,0.774482,NO,149,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.149,-4.272,3.123,,0.183,T,A,1.33,1.09,,,,HHO,-1.27767,0.175299,0.000325688,0.774482 beta-lactamase_V21E,beta-lactamase_21,TEM-1,beta-lactamase,P62593,0.774626,NO,21,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.873,-3.441,1.568,,,,,,,0.688,,93.01,OHH,-2.09633,0.221079,0.0028612,0.774626 kka2_1:2_F206S,kka2_1:2_206,Kka2,kka2_1:2,P00552,0.774668,NO,206,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.349,-3.736,2.387,,0.006,E,B,0.58,-1.21,0.978,,63.64,OHH,-1.04,0.295029,0.00936868,0.774668 kka2_1:4_A222C,kka2_1:4_222,Kka2,kka2_1:4,P00552,0.774721,NO,222,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.725,-4.44,3.715,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.168804,0.00207657,0.774721 kka2_1:8_R211K,kka2_1:8_211,Kka2,kka2_1:8,P00552,0.77474,NO,211,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-0.899,-2.904,2.005,,0.12,T,a,0.16,-0.39,0.615,,49.62,OBH,-0.966,0.100394,0.00204888,0.77474 kka2_1:8_R211K,kka2_1:8_211,Kka2,kka2_1:8,P00552,0.77474,NO,211,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-0.899,-2.904,2.005,,0.12,T,a,0.16,-0.39,0.615,,49.62,OBH,-0.966,0.100394,0.00204888,0.77474 beta-lactamase_0_D48T,beta-lactamase_0_48,TEM-1,beta-lactamase_0,P62593,0.774787,NO,48,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.101,-3.511,2.41,,0.189,E,B,0.75,0.21,17.825,17.825,50.35,HAH,-1.62467,0.0500837,0.0027273,0.774787 kka2_1:2_I29R,kka2_1:2_29,Kka2,kka2_1:2,P00552,0.774806,NO,29,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.692,-4.083,2.391,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.295029,0.00619521,0.774806 beta-lactamase_625_E195L,beta-lactamase_625_195,TEM-1,beta-lactamase_625,P62593,0.774807,NO,195,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.186,-3.741,1.555,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.213352,0.00496565,0.774807 kka2_1:2_A56M,kka2_1:2_56,Kka2,kka2_1:2,P00552,0.774816,NO,56,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.083,-4.776,2.693,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.295029,0.00717715,0.774816 kka2_1:8_R211G,kka2_1:8_211,Kka2,kka2_1:8,P00552,0.774828,NO,211,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-0.899,-3.41,2.511,,0.12,T,a,0.16,-0.39,0.615,,49.62,OBH,-0.966,0.100394,0.00204888,0.774828 kka2_1:8_R211G,kka2_1:8_211,Kka2,kka2_1:8,P00552,0.774828,NO,211,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-0.899,-3.41,2.511,,0.12,T,a,0.16,-0.39,0.615,,49.62,OBH,-0.966,0.100394,0.00204888,0.774828 kka2_1:2_E142W,kka2_1:2_142,Kka2,kka2_1:2,P00552,0.774833,NO,142,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.221,-5.578,3.357,,0.471,H,A,1.52,0.85,3.693,,65.53,HAB,-2.08033,0.295029,0.00748883,0.774833 beta-lactamase_P12R,beta-lactamase_12,TEM-1,beta-lactamase,P62593,0.774836,NO,12,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-2.016,-3.954,1.938,,,,,,,2.88,,72.73,HOH,-2.05167,0.221079,0.00241653,0.774836 kka2_1:4_P109D,kka2_1:4_109,Kka2,kka2_1:4,P00552,0.774838,NO,109,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.412,-2.934,1.522,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.168804,0.0070929,0.774838 Pab1_L133A,Pab1_133,Pab1,Pab1,P04147,0.774859,NO,133,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.039,-2.895,1.856,,0.015,,B,1.75,1.03,,,,PHB,-1.22,0.175299,0.000345939,0.774859 beta-lactamase_0_I125H,beta-lactamase_0_125,TEM-1,beta-lactamase_0,P62593,0.774868,NO,125,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.441,-4.965,3.524,,,H,A,0.48,-0.7,1.874,,63.29,HHP,-1.248,0.0500837,0.00383964,0.774868 beta-lactamase_2500_R176L,beta-lactamase_2500_176,TEM-1,beta-lactamase_2500,P62593,0.774873,NO,176,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-0.863,-3.358,2.495,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.361275,0.00105554,0.774873 kka2_1:8_D261G,kka2_1:8_261,Kka2,kka2_1:8,P00552,0.774893,NO,261,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.708,-3.161,2.453,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.100394,0.0224846,0.774893 kka2_1:8_D261G,kka2_1:8_261,Kka2,kka2_1:8,P00552,0.774893,NO,261,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.708,-3.161,2.453,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.100394,0.0224846,0.774893 beta-lactamase_0_H156Y,beta-lactamase_0_156,TEM-1,beta-lactamase_0,P62593,0.774914,NO,156,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-3.156,-4.359,1.203,,0.753,S,A,0.17,-0.6,23.367,23.367,77.62,ABH,-1.932,0.0500837,0.00468596,0.774914 beta-lactamase_156_G43C,beta-lactamase_156_43,TEM-1,beta-lactamase_156,P62593,0.774948,NO,43,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.62,-5.087,4.467,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.111618,0.00120151,0.774948 kka2_1:1_A13T,kka2_1:1_13,Kka2,kka2_1:1,P00552,0.774959,NO,13,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.248,-2.994,0.746,,0.689,G,A,0.46,0.99,25.015,25.015,92.05,OHH,-1.646,0.520039,0.00784241,0.774959 kka2_1:4_G88A,kka2_1:4_88,Kka2,kka2_1:4,P00552,0.774982,NO,88,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.689,-2.52,0.831,,0.54,S,l,0.29,1.51,7.899,,65.53,HOB,-1.718,0.168804,0.00685559,0.774982 kka2_1:4_I228L,kka2_1:4_228,Kka2,kka2_1:4,P00552,0.774989,NO,228,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.142,-1.811,0.669,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.168804,0.00458834,0.774989 kka2_1:8_S32A,kka2_1:8_32,Kka2,kka2_1:8,P00552,0.774991,NO,32,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-0.804,-2.656,1.852,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.100394,0.00149998,0.774991 kka2_1:8_S32A,kka2_1:8_32,Kka2,kka2_1:8,P00552,0.774991,NO,32,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-0.804,-2.656,1.852,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.100394,0.00149998,0.774991 kka2_1:1_A25C,kka2_1:1_25,Kka2,kka2_1:1,P00552,0.775069,NO,25,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.496,-5.199,2.703,,0.427,E,B,0.46,-0.47,6.872,6.872,65.53,HHP,-2.15167,0.520039,0.00595636,0.775069 beta-lactamase_D174G,beta-lactamase_174,TEM-1,beta-lactamase,P62593,0.775184,NO,174,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.738,-3.133,2.395,5.44133,0.238,,B,1.22,-0.1,,,,PAA,-1.91233,0.221079,0.00125633,0.775184 kka2_1:2_L47P,kka2_1:2_47,Kka2,kka2_1:2,P00552,0.775242,NO,47,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.265,-4.146,2.881,,0.139,E,B,0.55,-0.86,2.369,,63.26,HHH,-1.77933,0.295029,0.00509386,0.775242 kka2_1:8_F256M,kka2_1:8_256,Kka2,kka2_1:8,P00552,0.775284,NO,256,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.49,-4.553,3.063,,,H,A,1.62,-0.78,1.713,,53.03,HHH,-1.423,0.100394,0.0132841,0.775284 kka2_1:8_F256M,kka2_1:8_256,Kka2,kka2_1:8,P00552,0.775284,NO,256,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.49,-4.553,3.063,,,H,A,1.62,-0.78,1.713,,53.03,HHH,-1.423,0.100394,0.0132841,0.775284 kka2_1:4_L102C,kka2_1:4_102,Kka2,kka2_1:4,P00552,0.775334,NO,102,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.804,-4.689,3.885,,,T,A,0.55,-1.17,0.65,,42.42,AHH,-1.398,0.168804,0.00201332,0.775334 beta-lactamase_G114A,beta-lactamase_114,TEM-1,beta-lactamase,P62593,0.775546,NO,114,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.094,-2.444,1.35,4.92659,0.011,,p,0.77,0.35,2.148,,41.61,AOH,-1.43733,0.221079,0.00224919,0.775546 beta-lactamase_0_W208G,beta-lactamase_0_208,TEM-1,beta-lactamase_0,P62593,0.775582,NO,208,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-0.818,-3.358,2.54,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.0500837,0.00126609,0.775582 gb1_E282V,gb1_282,gb1,gb1,P06654,0.775637,NO,282,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.318,-3.369,2.051,,,,,,,1.075,,35.71,PAO,-1.573,0.177985,0.00209643,0.775637 kka2_1:1_S54R,kka2_1:1_54,Kka2,kka2_1:1,P00552,0.775661,NO,54,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.471,-2.798,0.327,,0.408,S,b,0.27,1.01,6.085,,71.59,HPO,-2.259,0.520039,0.00782867,0.775661 kka2_1:1_G99C,kka2_1:1_99,Kka2,kka2_1:1,P00552,0.775702,NO,99,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.596,-5.115,4.519,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.520039,0.00186055,0.775702 kka2_1:4_D101A,kka2_1:4_101,Kka2,kka2_1:4,P00552,0.775762,NO,101,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.028,-2.654,1.626,,0.213,E,B,0.75,-1.24,8.707,,63.64,PAH,-1.534,0.168804,0.00423361,0.775762 beta-lactamase_0_D99F,beta-lactamase_0_99,TEM-1,beta-lactamase_0,P62593,0.775839,NO,99,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.191,-4.277,3.086,,0.402,G,A,0.75,0.36,0.374,,64.69,PAH,-1.794,0.0500837,0.00305446,0.775839 beta-lactamase_T131V,beta-lactamase_131,TEM-1,beta-lactamase,P62593,0.775956,NO,131,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.328,-3.345,2.017,5.0548,,H,A,0.53,-0.69,3.306,,67.48,PPH,-1.00867,0.221079,0.00345886,0.775956 beta-lactamase_156_Y103K,beta-lactamase_156_103,TEM-1,beta-lactamase_156,P62593,0.776087,NO,103,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-1.33,-3.666,2.336,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.111618,0.00443048,0.776087 beta-lactamase_V82G,beta-lactamase_82,TEM-1,beta-lactamase,P62593,0.776096,NO,82,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.325,-2.644,1.319,5.27777,0.267,H,A,0.96,0.08,1.379,,93.01,BHA,-1.28567,0.221079,0.00397046,0.776096 beta-lactamase_0_L223W,beta-lactamase_0_223,TEM-1,beta-lactamase_0,P62593,0.776106,NO,223,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.055,-5.101,4.046,,0.27,,B,0.55,0.09,1.633,,74.48,HHO,-1.35033,0.0500837,0.00372793,0.776106 kka2_1:4_V186C,kka2_1:4_186,Kka2,kka2_1:4,P00552,0.776122,NO,186,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.011,-4.765,3.754,,,E,B,0.44,-0.61,0.679,,45.83,HHP,-1.10967,0.168804,0.00409703,0.776122 kka2_1:8_D220A,kka2_1:8_220,Kka2,kka2_1:8,P00552,0.776163,NO,220,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.787,-3.298,2.511,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.100394,0.00158066,0.776163 kka2_1:8_D220A,kka2_1:8_220,Kka2,kka2_1:8,P00552,0.776163,NO,220,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.787,-3.298,2.511,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.100394,0.00158066,0.776163 Pab1_L186E,Pab1_186,Pab1,Pab1,P04147,0.776236,NO,186,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.783,-3.735,1.952,,,,,,,,,,HHP,-1.56967,0.175299,0.00154968,0.776236 beta-lactamase_0_W208A,beta-lactamase_0_208,TEM-1,beta-lactamase_0,P62593,0.776237,NO,208,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-0.818,-3.528,2.71,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.0500837,0.00126609,0.776237 beta-lactamase_0_Q97E,beta-lactamase_0_97,TEM-1,beta-lactamase_0,P62593,0.776255,NO,97,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.072,-2.167,0.095,,0.823,G,A,0.64,2.42,16.954,16.954,77.62,PPP,-2.43833,0.0500837,0.0045116,0.776255 gb1_Y259Q,gb1_259,gb1,gb1,P06654,0.776285,NO,259,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-1.78,-3.971,2.191,,,,,,,0.131,,11.83,PHH,-1.787,0.177985,0.00464313,0.776285 beta-lactamase_G52F,beta-lactamase_52,TEM-1,beta-lactamase,P62593,0.776369,NO,52,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.149,-4.393,3.244,5.12093,0.299,,l,0.77,-0.04,2.103,,64.69,POB,-1.66267,0.221079,0.00340138,0.776369 beta-lactamase_D231Q,beta-lactamase_231,TEM-1,beta-lactamase,P62593,0.776403,NO,231,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.816,-3.637,2.821,5.06651,,E,B,1.22,-1.06,0.319,,65.38,HAB,-0.994,0.221079,0.00107395,0.776403 beta-lactamase_0_L111R,beta-lactamase_0_111,TEM-1,beta-lactamase_0,P62593,0.776424,NO,111,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.76,-4.077,2.317,,0.328,T,A,0.55,0.93,1.966,,64.34,BHP,-1.884,0.0500837,0.00480671,0.776424 beta-lactamase_2500_R176N,beta-lactamase_2500_176,TEM-1,beta-lactamase_2500,P62593,0.776442,NO,176,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-0.863,-3.448,2.585,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.361275,0.00105554,0.776442 beta-lactamase_2500_L73T,beta-lactamase_2500_73,TEM-1,beta-lactamase_2500,P62593,0.776467,NO,73,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.507,-3.582,2.075,,,H,A,0.55,-0.64,2.178,,67.83,HHH,-1.487,0.361275,0.00488983,0.776467 WW_domain_S184C,WW_domain_184,Yap65,WW_domain,P46937,0.776505,NO,184,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.363,-4.477,3.114,5.06696,,,,,,,,,PPO,-1.39133,0.153962,0.00231095,0.776505 kka2_1:1_T125P,kka2_1:1_125,Kka2,kka2_1:1,P00552,0.776507,NO,125,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.622,-3.993,1.371,,0.791,T,A,0.22,0.33,1.972,,92.05,BPH,-1.56933,0.520039,0.00821755,0.776507 kka2_1:2_P179F,kka2_1:2_179,Kka2,kka2_1:2,P00552,0.77652,NO,179,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.974,-4.355,3.381,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.295029,0.00298346,0.77652 kka2_1:8_K112C,kka2_1:8_112,Kka2,kka2_1:8,P00552,0.77652,NO,112,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-2.491,-3.546,1.055,,0.076,H,A,1.3,-1.37,10.58,10.58,56.06,ABH,-2.00133,0.100394,0.00645389,0.77652 kka2_1:8_K112C,kka2_1:8_112,Kka2,kka2_1:8,P00552,0.77652,NO,112,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-2.491,-3.546,1.055,,0.076,H,A,1.3,-1.37,10.58,10.58,56.06,ABH,-2.00133,0.100394,0.00645389,0.77652 beta-lactamase_W208D,beta-lactamase_208,TEM-1,beta-lactamase,P62593,0.776521,NO,208,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-0.818,-4.144,3.326,5.26277,0.067,H,A,0.99,-0.65,,,,AHH,-1.44133,0.221079,0.00126609,0.776521 kka2_1:8_G201F,kka2_1:8_201,Kka2,kka2_1:8,P00552,0.77665,NO,201,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.56,-4.498,2.938,,0.149,T,l,0.75,-0.57,2.152,,52.65,POB,-1.92233,0.100394,0.00820117,0.77665 kka2_1:8_G201F,kka2_1:8_201,Kka2,kka2_1:8,P00552,0.77665,NO,201,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.56,-4.498,2.938,,0.149,T,l,0.75,-0.57,2.152,,52.65,POB,-1.92233,0.100394,0.00820117,0.77665 PSD95pdz3_D348Y,PSD95pdz3_348,PSD95pdz3,PSD95pdz3,P31016,0.776651,NO,348,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.264,-4.069,2.805,5.02473,,,,,16.8925,,,,HAH,-1.306,0.0758425,0.000731866,0.776651 beta-lactamase_2500_E102W,beta-lactamase_2500_102,TEM-1,beta-lactamase_2500,P62593,0.776658,NO,102,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.118,-5.479,3.361,,0.722,S,B,1.04,1.82,1.336,,73.08,HAH,-1.581,0.361275,0.00486633,0.776658 beta-lactamase_0_G253S,beta-lactamase_0_253,TEM-1,beta-lactamase_0,P62593,0.776672,NO,253,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.0500837,0.00786358,0.776672 PSD95pdz3_I336E,PSD95pdz3_336,PSD95pdz3,PSD95pdz3,P31016,0.776701,NO,336,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.63,-3.572,1.942,5.11321,,,,,13.6363,,,,OHH,-1.38733,0.0758425,0.000887923,0.776701 kka2_1:2_G95C,kka2_1:2_95,Kka2,kka2_1:2,P00552,0.776735,NO,95,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-2.403,-5.049,2.646,,0.126,E,B,0.29,-0.74,0.359,,71.59,HOA,-2.198,0.295029,0.00743616,0.776735 kka2_1:4_R140C,kka2_1:4_140,Kka2,kka2_1:4,P00552,0.776768,NO,140,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.351,-5.118,3.767,,0.12,H,A,1.2,0.2,2.561,,53.03,BBH,-1.885,0.168804,0.00430167,0.776768 kka2_1:4_R38L,kka2_1:4_38,Kka2,kka2_1:4,P00552,0.776812,NO,38,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.207,-1.87,0.663,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.168804,0.00372499,0.776812 kka2_1:1_L47R,kka2_1:1_47,Kka2,kka2_1:1,P00552,0.776841,NO,47,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.265,-2.763,1.498,,0.139,E,B,0.55,-0.86,14.593,14.593,63.26,HHH,-1.77933,0.520039,0.00509386,0.776841 kka2_1:8_W91M,kka2_1:8_91,Kka2,kka2_1:8,P00552,0.776877,NO,91,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-1.178,-4.551,3.373,,0.077,E,B,1.51,0.27,2.51,,48.48,AHH,-1.51,0.100394,0.00358653,0.776877 kka2_1:8_W91M,kka2_1:8_91,Kka2,kka2_1:8,P00552,0.776877,NO,91,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-1.178,-4.551,3.373,,0.077,E,B,1.51,0.27,2.51,,48.48,AHH,-1.51,0.100394,0.00358653,0.776877 kka2_1:1_D23E,kka2_1:1_23,Kka2,kka2_1:1,P00552,0.776894,NO,23,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.459,-2.431,-0.028,,0.695,E,B,0.75,-0.65,2.655,,65.53,HAH,-1.94033,0.520039,0.007195,0.776894 kka2_1:8_D62L,kka2_1:8_62,Kka2,kka2_1:8,P00552,0.776909,NO,62,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.591,-3.008,1.417,,0.262,H,A,0.29,0.08,5.58,,64.39,PAA,-1.77833,0.100394,0.00744243,0.776909 kka2_1:8_D62L,kka2_1:8_62,Kka2,kka2_1:8,P00552,0.776909,NO,62,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.591,-3.008,1.417,,0.262,H,A,0.29,0.08,5.58,,64.39,PAA,-1.77833,0.100394,0.00744243,0.776909 beta-lactamase_A23V,beta-lactamase_23,TEM-1,beta-lactamase,P62593,0.776984,NO,23,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.548,-3.35,1.802,,,,,,,0.801,,93.01,HHB,-2.235,0.221079,0.00245563,0.776984 beta-lactamase_39_I258W,beta-lactamase_39_258,TEM-1,beta-lactamase_39,P62593,0.777033,NO,258,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.0495842,0.007931,0.777033 beta-lactamase_V82E,beta-lactamase_82,TEM-1,beta-lactamase,P62593,0.777053,NO,82,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.325,-3.751,2.426,5.27777,0.267,H,A,0.96,0.08,1.379,,93.01,BHA,-1.28567,0.221079,0.00397046,0.777053 beta-lactamase_I140S,beta-lactamase_140,TEM-1,beta-lactamase,P62593,0.777056,NO,140,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.733,-3.688,1.955,5.29918,0.128,H,A,1,0.41,1.16,,73.08,PHO,-1.48733,0.221079,0.00597777,0.777056 beta-lactamase_G114S,beta-lactamase_114,TEM-1,beta-lactamase,P62593,0.777062,NO,114,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.094,-2.588,1.494,4.92659,0.011,,p,0.77,0.35,2.148,,41.61,AOH,-1.43733,0.221079,0.00224919,0.777062 kka2_1:4_G245R,kka2_1:4_245,Kka2,kka2_1:4,P00552,0.777072,NO,245,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.812,-3.916,3.104,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.168804,0.00683899,0.777072 beta-lactamase_0_T186D,beta-lactamase_0_186,TEM-1,beta-lactamase_0,P62593,0.777077,NO,186,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.522,-2.935,0.413,,0.396,H,A,0.22,-0.28,16.606,16.606,77.62,HPP,-1.77633,0.0500837,0.00485034,0.777077 beta-lactamase_0_S104L,beta-lactamase_0_104,TEM-1,beta-lactamase_0,P62593,0.777177,NO,104,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.015,-3.359,2.344,,0.04,,b,0.27,0.57,1.148,,63.29,HPO,-1.05267,0.0500837,0.00218083,0.777177 beta-lactamase_P105S,beta-lactamase_105,TEM-1,beta-lactamase,P62593,0.777212,NO,105,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.813,-2.526,1.713,5.08236,0.226,T,A,0.98,0.8,1.154,,63.29,POH,-1.01533,0.221079,0.0011981,0.777212 beta-lactamase_0_R63H,beta-lactamase_0_63,TEM-1,beta-lactamase_0,P62593,0.777234,NO,63,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-0.943,-4.313,3.37,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.0500837,0.00126938,0.777234 beta-lactamase_39_F64A,beta-lactamase_39_64,TEM-1,beta-lactamase_39,P62593,0.777234,NO,64,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-0.841,-3.303,2.462,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.0495842,0.000947691,0.777234 kka2_1:1_S32G,kka2_1:1_32,Kka2,kka2_1:1,P00552,0.777395,NO,32,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-0.804,-2.936,2.132,,0.768,S,b,0.27,3.75,,,,OPA,-1.74533,0.520039,0.00149998,0.777395 kka2_1:8_Q219K,kka2_1:8_219,Kka2,kka2_1:8,P00552,0.777395,NO,219,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-0.93,-3.033,2.103,,0.088,H,A,0.4,-0.85,0.897,,50,HPA,-1.05167,0.100394,0.00237913,0.777395 kka2_1:8_Q219K,kka2_1:8_219,Kka2,kka2_1:8,P00552,0.777395,NO,219,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-0.93,-3.033,2.103,,0.088,H,A,0.4,-0.85,0.897,,50,HPA,-1.05167,0.100394,0.00237913,0.777395 beta-lactamase_0_K254A,beta-lactamase_0_254,TEM-1,beta-lactamase_0,P62593,0.777398,NO,254,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.0500837,0.00369,0.777398 hsp90_W585V,hsp90_585,hsp90,hsp90,P02829,0.777409,NO,585,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-4.251,-2.682,0,5.31455,0.508,,B,1.22,0.43,,,,OHP,-3.17533,0.368192,0.000222939,0.777409 Pab1_K166G,Pab1_166,Pab1,Pab1,P04147,0.77742,NO,166,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.262,-3.251,1.989,,0.299,,l,,0,,,,PBO,-1.21033,0.175299,0.0011038,0.77742 beta-lactamase_0_T198I,beta-lactamase_0_198,TEM-1,beta-lactamase_0,P62593,0.777487,NO,198,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.168,-3.831,1.663,,0.489,,B,0.22,-0.13,9.874,,73.78,HPH,-1.98767,0.0500837,0.004311,0.777487 gb1_G235Y,gb1_235,gb1,gb1,P06654,0.777572,NO,235,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.419,-4.08,2.661,,,,,,,0.476,,11.83,POB,-1.86433,0.177985,0.00297491,0.777572 kka2_1:1_D62Y,kka2_1:1_62,Kka2,kka2_1:1,P00552,0.777596,NO,62,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.591,-4.391,2.8,,0.262,H,A,0.75,0.08,10.048,10.048,64.39,PAA,-1.77833,0.520039,0.00744243,0.777596 kka2_1:8_V214A,kka2_1:8_214,Kka2,kka2_1:8,P00552,0.777751,NO,214,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.261,-3.113,1.852,,0.117,E,B,1.48,-0.31,1.859,,64.39,OHH,-0.941667,0.100394,0.00692782,0.777751 kka2_1:8_V214A,kka2_1:8_214,Kka2,kka2_1:8,P00552,0.777751,NO,214,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.261,-3.113,1.852,,0.117,E,B,1.48,-0.31,1.859,,64.39,OHH,-0.941667,0.100394,0.00692782,0.777751 beta-lactamase_39_I45K,beta-lactamase_39_45,TEM-1,beta-lactamase_39,P62593,0.777761,NO,45,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-2.421,-3.76,1.339,,,E,B,0.48,-0.3,2.256,,77.62,HHA,-2.30267,0.0495842,0.00452842,0.777761 beta-lactamase_0_D83I,beta-lactamase_0_83,TEM-1,beta-lactamase_0,P62593,0.777776,NO,83,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.066,-4.081,3.015,,0.354,H,A,0.75,0.22,0.617,,48.95,HAH,-1.34733,0.0500837,0.00205968,0.777776 beta-lactamase_0_L167F,beta-lactamase_0_167,TEM-1,beta-lactamase_0,P62593,0.77784,NO,167,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.138,-3.813,2.675,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.0500837,0.00303566,0.77784 beta-lactamase_0_A133V,beta-lactamase_0_133,TEM-1,beta-lactamase_0,P62593,0.777848,NO,133,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.186,-3.341,2.155,,,H,A,0.46,-0.86,2.148,,67.83,HHP,-0.988333,0.0500837,0.00468022,0.777848 WW_domain_T182L,WW_domain_182,Yap65,WW_domain,P46937,0.777886,NO,182,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.149,-2.91,1.761,6.20597,,,,,,,,,BPP,-1.483,0.153962,0.00294574,0.777886 kka2_1:8_R38G,kka2_1:8_38,Kka2,kka2_1:8,P00552,0.777945,NO,38,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.207,-3.596,2.389,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.100394,0.00372499,0.777945 kka2_1:8_R38G,kka2_1:8_38,Kka2,kka2_1:8,P00552,0.777945,NO,38,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.207,-3.596,2.389,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.100394,0.00372499,0.777945 kka2_1:4_L107F,kka2_1:4_107,Kka2,kka2_1:4,P00552,0.777956,NO,107,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.238,-3.877,2.639,,0.197,.,B,0.55,-1.1,0.398,,71.59,BHH,-2.143,0.168804,0.00561937,0.777956 kka2_1:8_H135G,kka2_1:8_135,Kka2,kka2_1:8,P00552,0.778041,NO,135,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-1.331,-3.471,2.14,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.100394,0.00532566,0.778041 kka2_1:8_H135G,kka2_1:8_135,Kka2,kka2_1:8,P00552,0.778041,NO,135,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-1.331,-3.471,2.14,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.100394,0.00532566,0.778041 beta-lactamase_N134D,beta-lactamase_134,TEM-1,beta-lactamase,P62593,0.778055,NO,134,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-0.879,-3.087,2.208,5.07245,0.138,H,A,0.09,-0.6,1.441,,53.15,HPH,-1.02233,0.221079,0.000644786,0.778055 beta-lactamase_0_R176G,beta-lactamase_0_176,TEM-1,beta-lactamase_0,P62593,0.778075,NO,176,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-0.863,-3.358,2.495,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.0500837,0.00105554,0.778075 beta-lactamase_0_G43E,beta-lactamase_0_43,TEM-1,beta-lactamase_0,P62593,0.778109,NO,43,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.62,-3.665,3.045,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.0500837,0.00120151,0.778109 beta-lactamase_V21D,beta-lactamase_21,TEM-1,beta-lactamase,P62593,0.778199,NO,21,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.873,-3.764,1.891,,,,,,,0.688,,93.01,OHH,-2.09633,0.221079,0.0028612,0.778199 beta-lactamase_0_A40E,beta-lactamase_0_40,TEM-1,beta-lactamase_0,P62593,0.778203,NO,40,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.402,-3.641,2.239,,0.155,S,B,0.46,0.21,0.783,,73.78,OHB,-1.40267,0.0500837,0.00490026,0.778203 beta-lactamase_0_A124M,beta-lactamase_0_124,TEM-1,beta-lactamase_0,P62593,0.778206,NO,124,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.181,-4.519,3.338,,,H,A,0.46,-0.9,1.876,,64.34,HHH,-1.152,0.0500837,0.00481399,0.778206 beta-lactamase_0_P60Y,beta-lactamase_0_60,TEM-1,beta-lactamase_0,P62593,0.778227,NO,60,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-2.469,-4.292,1.823,,0.256,T,A,0.52,-0.56,3.653,,77.62,BOA,-1.97633,0.0500837,0.00521318,0.778227 kka2_1:4_G245L,kka2_1:4_245,Kka2,kka2_1:4,P00552,0.778267,NO,245,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.812,-3.785,2.973,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.168804,0.00683899,0.778267 beta-lactamase_K30W,beta-lactamase_30,TEM-1,beta-lactamase,P62593,0.778273,NO,30,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-2.307,-5.404,3.097,5.30605,0.142,H,A,1.82,-0.65,2.434,,93.01,HBH,-2.32833,0.221079,0.00448593,0.778273 beta-lactamase_V214F,beta-lactamase_214,TEM-1,beta-lactamase,P62593,0.778314,NO,214,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.299,-3.997,2.698,5.74008,0.375,S,A,1.19,-0.44,1.899,,74.48,BHH,-1.53733,0.221079,0.00628442,0.778314 beta-lactamase_0_T107S,beta-lactamase_0_107,TEM-1,beta-lactamase_0,P62593,0.778366,NO,107,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.117,-1.871,0.754,,,G,A,0.22,-0.06,3.73,,67.83,HPA,-1.265,0.0500837,0.00239347,0.778366 beta-lactamase_0_A133F,beta-lactamase_0_133,TEM-1,beta-lactamase_0,P62593,0.778437,NO,133,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.186,-4.224,3.038,,,H,A,0.46,-0.86,2.148,,67.83,HHP,-0.988333,0.0500837,0.00468022,0.778437 beta-lactamase_0_L47Y,beta-lactamase_0_47,TEM-1,beta-lactamase_0,P62593,0.778438,NO,47,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.876,-3.117,1.241,,0.007,E,B,0.55,0.2,1.024,,67.83,AHA,-1.639,0.0500837,0.00439844,0.778438 kka2_1:4_Q27F,kka2_1:4_27,Kka2,kka2_1:4,P00552,0.778438,NO,27,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-1.659,-4.291,2.632,,0.608,,A,0.4,0.71,1.498,,65.53,PPP,-1.90733,0.168804,0.00595365,0.778438 beta-lactamase_39_E195L,beta-lactamase_39_195,TEM-1,beta-lactamase_39,P62593,0.778455,NO,195,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.186,-3.741,1.555,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.0495842,0.00496565,0.778455 beta-lactamase_L74C,beta-lactamase_74,TEM-1,beta-lactamase,P62593,0.778485,NO,74,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.296,-4.647,3.351,5.50288,,H,A,1.75,-0.91,1.581,,50,HHO,-1.34933,0.221079,0.00493255,0.778485 beta-lactamase_0_G114H,beta-lactamase_0_114,TEM-1,beta-lactamase_0,P62593,0.778593,NO,114,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.094,-4.665,3.571,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.0500837,0.00224919,0.778593 beta-lactamase_2500_V42W,beta-lactamase_2500_42,TEM-1,beta-lactamase_2500,P62593,0.778614,NO,42,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.564,-5.336,3.772,,0.017,E,B,0.44,-0.51,1.86,,63.99,BHO,-1.042,0.361275,0.00404515,0.778614 beta-lactamase_0_G142W,beta-lactamase_0_142,TEM-1,beta-lactamase_0,P62593,0.778627,NO,142,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.707,-5.146,4.439,,0.034,,p,0.29,-0.64,1.947,,64.69,OOO,-0.834,0.0500837,0.00060149,0.778627 kka2_1:4_T28R,kka2_1:4_28,Kka2,kka2_1:4,P00552,0.778637,NO,28,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.883,-3.259,1.376,,0.353,S,B,0.82,2.02,4.415,,63.64,PPH,-1.74467,0.168804,0.00743084,0.778637 kka2_1:8_V113L,kka2_1:8_113,Kka2,kka2_1:8,P00552,0.778687,NO,113,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.233,-2.374,1.141,,0.008,H,A,1.48,-1.17,1.254,,52.27,BHP,-2.08367,0.100394,0.00650191,0.778687 kka2_1:8_V113L,kka2_1:8_113,Kka2,kka2_1:8,P00552,0.778687,NO,113,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.233,-2.374,1.141,,0.008,H,A,1.48,-1.17,1.254,,52.27,BHP,-2.08367,0.100394,0.00650191,0.778687 beta-lactamase_0_L248R,beta-lactamase_0_248,TEM-1,beta-lactamase_0,P62593,0.778689,NO,248,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.0500837,0.00428493,0.778689 beta-lactamase_N272G,beta-lactamase_272,TEM-1,beta-lactamase,P62593,0.778718,NO,272,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-1.127,-3.091,1.964,5.37826,0.081,H,A,0.09,-0.97,1.468,,63.64,BPB,-1.56333,0.221079,0.00545371,0.778718 kka2_1:4_R38E,kka2_1:4_38,Kka2,kka2_1:4,P00552,0.778766,NO,38,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.207,-3.518,2.311,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.168804,0.00372499,0.778766 beta-lactamase_A246Q,beta-lactamase_246,TEM-1,beta-lactamase,P62593,0.7788,NO,246,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.121,-4.263,2.142,4.78979,0.01,E,B,0.52,-1.01,1.26,,73.78,HHH,-1.55633,0.221079,0.00569458,0.7788 beta-lactamase_T267W,beta-lactamase_267,TEM-1,beta-lactamase,P62593,0.7788,NO,267,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.308,-5.553,3.245,5.28263,0.54,,B,0.69,-0.14,0.374,,73.78,HPH,-1.9,0.221079,0.0102128,0.7788 beta-lactamase_R81C,beta-lactamase_81,TEM-1,beta-lactamase,P62593,0.778811,NO,81,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.466,-5.147,3.681,5.12166,0.218,H,A,0.68,1.66,1.236,,50,PBH,-1.60667,0.221079,0.00499763,0.778811 Pab1_V171G,Pab1_171,Pab1,Pab1,P04147,0.778812,NO,171,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.113,-3.4,2.287,,0.008,E,b,0.23,-0.34,,,,HHB,-1.19733,0.175299,0.000298662,0.778812 beta-lactamase_625_I93C,beta-lactamase_625_93,TEM-1,beta-lactamase_625,P62593,0.778834,NO,93,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.401,-4.797,3.396,,0.128,E,B,0.48,0.44,1.524,,67.83,BHB,-1.873,0.213352,0.00527066,0.778834 gb1_A260G,gb1_260,gb1,gb1,P06654,0.778849,NO,260,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.486,-3.09,1.604,,,,,,,0.173,,9.6,HHP,-1.70967,0.177985,0.0055808,0.778849 kka2_1:2_I29H,kka2_1:2_29,Kka2,kka2_1:2,P00552,0.77894,NO,29,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.692,-4.894,3.202,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.295029,0.00619521,0.77894 beta-lactamase_625_E87H,beta-lactamase_625_87,TEM-1,beta-lactamase_625,P62593,0.778959,NO,87,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.421,-4.575,3.154,,0.048,,B,1.04,0.92,17.923,17.923,64.69,PAP,-1.969,0.213352,0.00337888,0.778959 beta-lactamase_0_T69L,beta-lactamase_0_69,TEM-1,beta-lactamase_0,P62593,0.778964,NO,69,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-0.973,-3.213,2.24,,,G,A,0.22,-1.24,0.505,,93.01,PPH,-1.01833,0.0500837,0.00127498,0.778964 kka2_1:1_Q219R,kka2_1:1_219,Kka2,kka2_1:1,P00552,0.778964,NO,219,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-0.93,-2.546,1.616,,0.088,H,A,0.4,-0.85,1.917,,50,HPA,-1.05167,0.520039,0.00237913,0.778964 beta-lactamase_0_V259A,beta-lactamase_0_259,TEM-1,beta-lactamase_0,P62593,0.77899,NO,259,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.0500837,0.0070773,0.77899 beta-lactamase_0_R63S,beta-lactamase_0_63,TEM-1,beta-lactamase_0,P62593,0.779043,NO,63,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-0.943,-3.435,2.492,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.0500837,0.00126938,0.779043 beta-lactamase_0_W227R,beta-lactamase_0_227,TEM-1,beta-lactamase_0,P62593,0.779054,NO,227,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-0.982,-4.182,3.2,,0.272,,B,0.47,-0.29,3.782,,74.48,OHH,-1.595,0.0500837,0.00226019,0.779054 beta-lactamase_V78C,beta-lactamase_78,TEM-1,beta-lactamase,P62593,0.779186,NO,78,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.459,-4.812,3.353,4.79197,,H,A,0.96,-0.47,1.132,,63.64,HHH,-1.17833,0.221079,0.00492501,0.779186 beta-lactamase_0_W208E,beta-lactamase_0_208,TEM-1,beta-lactamase_0,P62593,0.779237,NO,208,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-0.818,-3.89,3.072,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.0500837,0.00126609,0.779237 Pab1_I157S,Pab1_157,Pab1,Pab1,P04147,0.779237,NO,157,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.623,-3.499,1.876,,,,,,,1.439,,79.72,BHH,-1.28667,0.175299,0.0018103,0.779237 kka2_1:8_P109R,kka2_1:8_109,Kka2,kka2_1:8,P00552,0.779267,NO,109,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.412,-3.997,2.585,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.100394,0.0070929,0.779267 kka2_1:8_P109R,kka2_1:8_109,Kka2,kka2_1:8,P00552,0.779267,NO,109,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.412,-3.997,2.585,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.100394,0.0070929,0.779267 kka2_1:1_L184R,kka2_1:1_184,Kka2,kka2_1:1,P00552,0.779269,NO,184,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.496,-2.591,1.095,,0.489,E,B,0.55,-0.06,19.127,19.127,63.26,AHH,-1.24833,0.520039,0.00518742,0.779269 beta-lactamase_0_G154T,beta-lactamase_0_154,TEM-1,beta-lactamase_0,P62593,0.779281,NO,154,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.823,-3.619,2.796,,0.54,T,l,0.29,-0.56,3.629,,64.69,HOA,-1.635,0.0500837,0.00180205,0.779281 beta-lactamase_R41G,beta-lactamase_41,TEM-1,beta-lactamase,P62593,0.779311,NO,41,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-0.942,-3.321,2.379,5.69185,0.321,E,B,0.91,-0.07,4.357,,65.03,HBH,-1.30267,0.221079,0.00123327,0.779311 beta-lactamase_2500_S201T,beta-lactamase_2500_201,TEM-1,beta-lactamase_2500,P62593,0.779339,NO,201,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.183,-3.198,2.015,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.361275,0.00198815,0.779339 beta-lactamase_0_L55G,beta-lactamase_0_55,TEM-1,beta-lactamase_0,P62593,0.779347,NO,55,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.86,-3.665,1.805,,0.372,E,A,0.55,-0.36,1.967,,63.99,HHA,-2.247,0.0500837,0.00403741,0.779347 beta-lactamase_625_Q276P,beta-lactamase_625_276,TEM-1,beta-lactamase_625,P62593,0.779354,NO,276,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.213352,0.0191712,0.779354 beta-lactamase_E87Y,beta-lactamase_87,TEM-1,beta-lactamase,P62593,0.779469,NO,87,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.421,-4.262,2.841,5.41929,0.048,,B,0.52,0.92,1.754,,64.69,PAP,-1.969,0.221079,0.00337888,0.779469 gb1_A249V,gb1_249,gb1,gb1,P06654,0.779484,NO,249,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.739,-2.127,0.388,,,,,,,0.252,,44.87,AHH,-1.67367,0.177985,0.00333585,0.779484 kka2_1:8_E161T,kka2_1:8_161,Kka2,kka2_1:8,P00552,0.779499,NO,161,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.581,-2.315,0.734,,0.829,G,A,1.04,2.24,11.923,11.923,92.05,AAB,-1.861,0.100394,0.00760103,0.779499 kka2_1:8_E161T,kka2_1:8_161,Kka2,kka2_1:8,P00552,0.779499,NO,161,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.581,-2.315,0.734,,0.829,G,A,1.04,2.24,11.923,11.923,92.05,AAB,-1.861,0.100394,0.00760103,0.779499 beta-lactamase_0_I140A,beta-lactamase_0_140,TEM-1,beta-lactamase_0,P62593,0.779598,NO,140,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.733,-3.145,1.412,,0.128,H,A,0.48,0.41,4.714,,73.08,PHO,-1.48733,0.0500837,0.00597777,0.779598 beta-lactamase_0_W227I,beta-lactamase_0_227,TEM-1,beta-lactamase_0,P62593,0.779647,NO,227,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-0.982,-3.985,3.003,,0.272,,B,0.47,-0.29,3.782,,74.48,OHH,-1.595,0.0500837,0.00226019,0.779647 beta-lactamase_0_P181N,beta-lactamase_0_181,TEM-1,beta-lactamase_0,P62593,0.779673,NO,181,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.813,-3.924,3.111,,,H,A,0.52,-1.14,1.357,,61.54,HOH,-1.795,0.0500837,0.000703122,0.779673 WW_domain_G185R,WW_domain_185,Yap65,WW_domain,P46937,0.779689,NO,185,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.861,-3.71,2.849,6.22337,,,,,,,,,POP,-1.194,0.153962,0.00199178,0.779689 kka2_1:4_W236C,kka2_1:4_236,Kka2,kka2_1:4,P00552,0.779734,NO,236,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-1.363,-3.273,1.91,,0.303,H,A,0.47,-0.76,2.277,,48.48,AHH,-1.81267,0.168804,0.0088796,0.779734 Pab1_F149V,Pab1_149,Pab1,Pab1,P04147,0.779743,NO,149,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.149,-3.121,1.972,,0.183,T,A,1.33,1.09,,,,HHO,-1.27767,0.175299,0.000325688,0.779743 kka2_1:1_K175R,kka2_1:1_175,Kka2,kka2_1:1,P00552,0.779746,NO,175,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-2.897,-2.852,-0.045,,0.579,H,A,1.3,0.51,9.33,9.33,71.59,HBH,-1.82333,0.520039,0.00693093,0.779746 beta-lactamase_2500_V101E,beta-lactamase_2500_101,TEM-1,beta-lactamase_2500,P62593,0.779815,NO,101,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.295,-2.851,1.556,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.361275,0.00374492,0.779815 PSD95pdz3_G356V,PSD95pdz3_356,PSD95pdz3,PSD95pdz3,P31016,0.779923,NO,356,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.008,-3.435,2.427,4.8656,,,,,11.9575,,,,BOA,-1.22933,0.0758425,0.000623061,0.779923 Pab1_T145Y,Pab1_145,Pab1,Pab1,P04147,0.77997,NO,145,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.067,-3.98,2.913,,0.237,H,A,0.3,0.69,,,,APH,-1.135,0.175299,0.000331088,0.77997 beta-lactamase_0_S51P,beta-lactamase_0_51,TEM-1,beta-lactamase_0,P62593,0.780008,NO,51,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.526,-3.858,2.332,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.0500837,0.00504821,0.780008 kka2_1:4_E161F,kka2_1:4_161,Kka2,kka2_1:4,P00552,0.780063,NO,161,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.581,-4.379,2.798,,0.829,G,A,1.52,2.24,1.612,,92.05,AAB,-1.861,0.168804,0.00760103,0.780063 beta-lactamase_M66H,beta-lactamase_66,TEM-1,beta-lactamase,P62593,0.780069,NO,66,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.362,-4.866,3.504,5.29561,0.013,,A,1.3,-0.7,1.319,,73.08,OHH,-1.49567,0.221079,0.00412876,0.780069 kka2_1:4_L212C,kka2_1:4_212,Kka2,kka2_1:4,P00552,0.780202,NO,212,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.904,-4.688,3.784,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.168804,0.0031426,0.780202 beta-lactamase_A133C,beta-lactamase_133,TEM-1,beta-lactamase,P62593,0.780347,NO,133,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.186,-4.706,3.52,4.86423,,H,A,0.55,-0.86,2.649,,67.83,HHP,-0.988333,0.221079,0.00468022,0.780347 Pab1_N139E,Pab1_139,Pab1,Pab1,P04147,0.780376,NO,139,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-1.079,-3.032,1.953,,0.062,H,A,,-0.73,,,,APB,-1.09667,0.175299,0.000339145,0.780376 beta-lactamase_0_G39K,beta-lactamase_0_39,TEM-1,beta-lactamase_0,P62593,0.780428,NO,39,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.864,-2.703,0.839,,0.701,T,L,0.29,0.47,4.111,,77.62,HOH,-1.53633,0.0500837,0.00487611,0.780428 beta-lactamase_L89C,beta-lactamase_89,TEM-1,beta-lactamase,P62593,0.780441,NO,89,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.096,-4.756,3.66,5.41092,0.168,T,A,1.75,0.63,1.599,,64.34,PHO,-1.75767,0.221079,0.00207068,0.780441 kka2_1:4_G99Q,kka2_1:4_99,Kka2,kka2_1:4,P00552,0.780468,NO,99,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.596,-4.153,3.557,,0.368,S,g,0.29,-0.87,,,,OOP,-1.63067,0.168804,0.00186055,0.780468 WW_domain_A180G,WW_domain_180,Yap65,WW_domain,P46937,0.780473,NO,180,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.242,-2.858,1.616,6.02829,,,,,,0.627,,23.61,HHB,-1.37767,0.153962,0.00413929,0.780473 Pab1_V171S,Pab1_171,Pab1,Pab1,P04147,0.780485,NO,171,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.113,-3.428,2.315,,0.008,E,b,0.23,-0.34,,,,HHB,-1.19733,0.175299,0.000298662,0.780485 kka2_1:8_F171V,kka2_1:8_171,Kka2,kka2_1:8,P00552,0.780519,NO,171,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.326,-3.284,1.958,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.100394,0.00821426,0.780519 kka2_1:8_F171V,kka2_1:8_171,Kka2,kka2_1:8,P00552,0.780519,NO,171,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.326,-3.284,1.958,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.100394,0.00821426,0.780519 kka2_1:1_R143C,kka2_1:1_143,Kka2,kka2_1:1,P00552,0.780559,NO,143,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.525,-5.079,2.554,,0.325,H,A,0.16,1.22,3.6,,65.53,ABH,-1.86833,0.520039,0.00662247,0.780559 beta-lactamase_S51L,beta-lactamase_51,TEM-1,beta-lactamase,P62593,0.780571,NO,51,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.526,-3.495,1.969,5.06164,0.496,T,A,0.25,0.26,1.699,,72.73,PPO,-1.88467,0.221079,0.00504821,0.780571 PSD95pdz3_A376H,PSD95pdz3_376,PSD95pdz3,PSD95pdz3,P31016,0.780615,NO,376,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.307,-4.362,3.055,4.72134,,,,,17.108,,,,HHH,-1.49567,0.0758425,0.000341232,0.780615 kka2_1:1_R122S,kka2_1:1_122,Kka2,kka2_1:1,P00552,0.780635,NO,122,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.175,-2.833,0.658,,0.487,H,A,1.2,0.26,1.356,,71.59,BBH,-1.53833,0.520039,0.00736512,0.780635 beta-lactamase_A276D,beta-lactamase_276,TEM-1,beta-lactamase,P62593,0.780679,NO,276,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.144,-3.687,2.543,5.1387,0.117,H,A,0.52,-0.84,1.283,,44.06,HHA,-1.47,0.221079,0.0191712,0.780679 beta-lactamase_R255H,beta-lactamase_255,TEM-1,beta-lactamase,P62593,0.780681,NO,255,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.266,-3.271,1.005,5.55882,0.141,E,B,0.68,0.38,1.199,,63.99,PBH,-2.00433,0.221079,0.00499612,0.780681 gb1_V255D,gb1_255,gb1,gb1,P06654,0.780746,NO,255,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-3.127,-3.31,0.183,,,,,,,1.323,,45.54,BHH,-2.03867,0.177985,0.00408354,0.780746 beta-lactamase_0_D161E,beta-lactamase_0_161,TEM-1,beta-lactamase_0,P62593,0.780768,NO,161,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.891,-2.299,1.408,,0.341,,A,0.75,-0.52,0.795,,61.19,HAB,-0.961333,0.0500837,0.000897697,0.780768 kka2_1:1_L241D,kka2_1:1_241,Kka2,kka2_1:1,P00552,0.780772,NO,241,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.158,-4.14,2.982,,0.08,H,A,0.55,-0.82,1.685,,63.26,HHH,-1.58533,0.520039,0.0117299,0.780772 beta-lactamase_R271E,beta-lactamase_271,TEM-1,beta-lactamase,P62593,0.780812,NO,271,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.249,-3.346,2.097,5.24516,0.085,H,A,1.67,-0.05,0.474,,63.99,ABP,-1.36633,0.221079,0.00752082,0.780812 kka2_1:1_R147G,kka2_1:1_147,Kka2,kka2_1:1,P00552,0.780814,NO,147,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.123,-3.428,2.305,,0.094,H,A,1.2,0.97,2.578,,64.02,PBH,-1.98267,0.520039,0.00549168,0.780814 kka2_1:2_F48L,kka2_1:2_48,Kka2,kka2_1:2,P00552,0.780823,NO,48,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.453,-2.543,1.09,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.295029,0.00475422,0.780823 beta-lactamase_156_L146H,beta-lactamase_156_146,TEM-1,beta-lactamase_156,P62593,0.780825,NO,146,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.462,-4.92,3.458,,0.007,H,A,0.55,-0.56,1.578,,64.69,AHP,-1.656,0.111618,0.00474542,0.780825 beta-lactamase_P105R,beta-lactamase_105,TEM-1,beta-lactamase,P62593,0.780884,NO,105,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.813,-3.93,3.117,5.08236,0.226,T,A,0.98,0.8,1.154,,63.29,POH,-1.01533,0.221079,0.0011981,0.780884 beta-lactamase_G194I,beta-lactamase_194,TEM-1,beta-lactamase,P62593,0.780982,NO,194,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.396,-4.133,2.737,5.46622,0.276,S,b,0.77,0.36,3.593,,67.83,POA,-1.832,0.221079,0.00392163,0.780982 kka2_1:2_N195K,kka2_1:2_195,Kka2,kka2_1:2,P00552,0.781001,NO,195,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-0.836,-3.304,2.468,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.295029,0.00276134,0.781001 beta-lactamase_0_N134Q,beta-lactamase_0_134,TEM-1,beta-lactamase_0,P62593,0.781071,NO,134,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-0.879,-3.672,2.793,,0.138,H,A,0.61,-0.6,3.776,,53.15,HPH,-1.02233,0.0500837,0.000644786,0.781071 beta-lactamase_G142E,beta-lactamase_142,TEM-1,beta-lactamase,P62593,0.781088,NO,142,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.707,-3.628,2.921,4.55474,0.034,,p,0.77,-0.64,1.947,,64.69,OOO,-0.834,0.221079,0.00060149,0.781088 kka2_1:8_I115T,kka2_1:8_115,Kka2,kka2_1:8,P00552,0.781096,NO,115,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.606,-3.564,1.958,,0.105,H,A,1.52,-1.18,4.064,,65.53,PHH,-2.205,0.100394,0.00836567,0.781096 kka2_1:8_I115T,kka2_1:8_115,Kka2,kka2_1:8,P00552,0.781096,NO,115,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.606,-3.564,1.958,,0.105,H,A,1.52,-1.18,4.064,,65.53,PHH,-2.205,0.100394,0.00836567,0.781096 kka2_1:1_Y22S,kka2_1:1_22,Kka2,kka2_1:1,P00552,0.781132,NO,22,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-1.583,-2.891,1.308,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.520039,0.00598977,0.781132 kka2_1:2_A108M,kka2_1:2_108,Kka2,kka2_1:2,P00552,0.781137,NO,108,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.061,-4.804,2.743,,0.243,.,B,0.46,-1.34,2.462,,71.59,HHO,-1.57033,0.295029,0.00751209,0.781137 kka2_1:2_A229S,kka2_1:2_229,Kka2,kka2_1:2,P00552,0.78115,NO,229,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.739,-3.404,1.665,,0.32,H,A,0.46,-0.7,6.549,,63.64,HHA,-1.851,0.295029,0.00942138,0.78115 kka2_1:1_R147S,kka2_1:1_147,Kka2,kka2_1:1,P00552,0.781153,NO,147,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.123,-3.438,2.315,,0.094,H,A,1.2,0.97,2.578,,64.02,PBH,-1.98267,0.520039,0.00549168,0.781153 beta-lactamase_0_D207A,beta-lactamase_0_207,TEM-1,beta-lactamase_0,P62593,0.781158,NO,207,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.064,-2.585,0.521,,0.409,H,A,0.75,0.12,5.277,,77.62,HAH,-1.77033,0.0500837,0.00592942,0.781158 kka2_1:4_S104A,kka2_1:4_104,Kka2,kka2_1:4,P00552,0.781167,NO,104,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.436,-3.053,1.617,,0.536,T,A,0.27,-1.11,0.357,,63.64,HPP,-1.91433,0.168804,0.00555207,0.781167 beta-lactamase_2500_S51A,beta-lactamase_2500_51,TEM-1,beta-lactamase_2500,P62593,0.781195,NO,51,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.526,-2.32,0.794,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.361275,0.00504821,0.781195 beta-lactamase_0_G253V,beta-lactamase_0_253,TEM-1,beta-lactamase_0,P62593,0.781235,NO,253,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.0500837,0.00786358,0.781235 beta-lactamase_0_T198D,beta-lactamase_0_198,TEM-1,beta-lactamase_0,P62593,0.781245,NO,198,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.168,-3.544,1.376,,0.489,,B,0.22,-0.13,9.874,,73.78,HPH,-1.98767,0.0500837,0.004311,0.781245 beta-lactamase_625_G76Y,beta-lactamase_625_76,TEM-1,beta-lactamase_625,P62593,0.781293,NO,76,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.189,-4.36,3.171,,,H,A,0.29,-0.67,3.059,,67.83,OOH,-1.22267,0.213352,0.00476637,0.781293 kka2_1:1_D23Q,kka2_1:1_23,Kka2,kka2_1:1,P00552,0.781305,NO,23,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.459,-3.078,0.619,,0.695,E,B,0.75,-0.65,2.655,,65.53,HAH,-1.94033,0.520039,0.007195,0.781305 beta-lactamase_G114Y,beta-lactamase_114,TEM-1,beta-lactamase,P62593,0.781349,NO,114,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.094,-4.391,3.297,4.92659,0.011,,p,0.77,0.35,2.148,,41.61,AOH,-1.43733,0.221079,0.00224919,0.781349 beta-lactamase_R255I,beta-lactamase_255,TEM-1,beta-lactamase,P62593,0.781407,NO,255,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.266,-2.446,0.18,5.55882,0.141,E,B,0.68,0.38,1.199,,63.99,PBH,-2.00433,0.221079,0.00499612,0.781407 kka2_1:4_D134I,kka2_1:4_134,Kka2,kka2_1:4,P00552,0.781419,NO,134,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.969,-3.956,2.987,,0.421,B,B,0.75,0.31,0.733,,49.62,HAB,-1.057,0.168804,0.00270812,0.781419 E1_Ubiquitin_R72Q,E1_Ubiquitin_72,Uba1,E1_Ubiquitin,P0CG63,0.781609,NO,72,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.184,-3.266,2.082,,0.077,,B,0.16,-0.1,,,,HBH,-1.08733,0.18783,0.00129853,0.781609 beta-lactamase_0_Q97W,beta-lactamase_0_97,TEM-1,beta-lactamase_0,P62593,0.78169,NO,97,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.072,-5.457,3.385,,0.823,G,A,0.64,2.42,16.954,16.954,77.62,PPP,-2.43833,0.0500837,0.0045116,0.78169 beta-lactamase_0_V31G,beta-lactamase_0_31,TEM-1,beta-lactamase_0,P62593,0.781693,NO,31,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.822,-3.699,1.877,,,H,A,0.44,-0.46,4.126,,73.78,BHB,-2.03767,0.0500837,0.00478065,0.781693 beta-lactamase_0_L89S,beta-lactamase_0_89,TEM-1,beta-lactamase_0,P62593,0.781702,NO,89,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.096,-3.54,2.444,,0.168,T,A,0.55,0.63,2.373,,64.34,PHO,-1.75767,0.0500837,0.00207068,0.781702 beta-lactamase_0_S104T,beta-lactamase_0_104,TEM-1,beta-lactamase_0,P62593,0.781726,NO,104,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.015,-3.098,2.083,,0.04,,b,0.27,0.57,1.148,,63.29,HPO,-1.05267,0.0500837,0.00218083,0.781726 beta-lactamase_0_V78I,beta-lactamase_0_78,TEM-1,beta-lactamase_0,P62593,0.781728,NO,78,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.459,-1.96,0.501,,,H,A,0.44,-0.47,16.615,16.615,63.64,HHH,-1.17833,0.0500837,0.00492501,0.781728 beta-lactamase_0_P165M,beta-lactamase_0_165,TEM-1,beta-lactamase_0,P62593,0.78183,NO,165,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.373,-4.649,3.276,,0.203,T,A,0.52,-0.31,3.242,,73.78,AOA,-1.359,0.0500837,0.00549538,0.78183 hsp90_Q582D,hsp90_582,hsp90,hsp90,P02829,0.781849,NO,582,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-3.278,-2.847,0,4.91603,0.453,S,B,,0.67,,,,OPH,-3.249,0.368192,0.000222939,0.781849 beta-lactamase_625_D174T,beta-lactamase_625_174,TEM-1,beta-lactamase_625,P62593,0.781938,NO,174,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.738,-3.421,2.683,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.213352,0.00125633,0.781938 beta-lactamase_N130Y,beta-lactamase_130,TEM-1,beta-lactamase,P62593,0.781975,NO,130,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-0.798,-4.162,3.364,5.26686,0.069,H,A,1.08,-0.74,,,,APP,-0.980667,0.221079,0.000683376,0.781975 kka2_1:4_G74I,kka2_1:4_74,Kka2,kka2_1:4,P00552,0.78199,NO,74,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.18,-4.265,3.085,,0.621,T,l,0.75,0.2,1.032,,64.39,POH,-1.91667,0.168804,0.00587035,0.78199 gb1_E282K,gb1_282,gb1,gb1,P06654,0.781998,NO,282,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.318,-2.906,1.588,,,,,,,1.075,,35.71,PAO,-1.573,0.177985,0.00209643,0.781998 kka2_1:1_E59D,kka2_1:1_59,Kka2,kka2_1:1,P00552,0.782136,NO,59,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-0.952,-2.395,1.443,,0.187,.,L,1.04,0.62,2.648,,50.38,PAH,-1.53,0.520039,0.00280355,0.782136 kka2_1:8_I221S,kka2_1:8_221,Kka2,kka2_1:8,P00552,0.782182,NO,221,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.739,-3.764,2.025,,,H,A,1.52,-1.15,1.599,,71.59,AHH,-1.08367,0.100394,0.00945908,0.782182 kka2_1:8_I221S,kka2_1:8_221,Kka2,kka2_1:8,P00552,0.782182,NO,221,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.739,-3.764,2.025,,,H,A,1.52,-1.15,1.599,,71.59,AHH,-1.08367,0.100394,0.00945908,0.782182 beta-lactamase_0_V78M,beta-lactamase_0_78,TEM-1,beta-lactamase_0,P62593,0.782242,NO,78,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.459,-2.823,1.364,,,H,A,0.44,-0.47,16.615,16.615,63.64,HHH,-1.17833,0.0500837,0.00492501,0.782242 kka2_1:8_G95P,kka2_1:8_95,Kka2,kka2_1:8,P00552,0.782246,NO,95,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-2.403,-3.948,1.545,,0.126,E,B,0.75,-0.74,7.774,,71.59,HOA,-2.198,0.100394,0.00743616,0.782246 kka2_1:8_G95P,kka2_1:8_95,Kka2,kka2_1:8,P00552,0.782246,NO,95,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-2.403,-3.948,1.545,,0.126,E,B,0.75,-0.74,7.774,,71.59,HOA,-2.198,0.100394,0.00743616,0.782246 Ubiquitin_H68F,Ubiquitin_68,Uba1,Ubiquitin,P0CG48,0.782258,NO,68,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-1.869,-3.017,1.148,4.81902,0.194,E,B,0.72,-1.02,21.325,21.325,65.11,HBH,-1.583,0.205827,0.000925438,0.782258 Ubiquitin_K27Y,Ubiquitin_27,Uba1,Ubiquitin,P0CG48,0.782258,NO,27,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.064,-4.189,3.125,4.77438,0.086,H,A,2.89,-0.74,2.662,,27.01,HBH,-1.42667,0.205827,0.000767556,0.782258 beta-lactamase_A16E,beta-lactamase_16,TEM-1,beta-lactamase,P62593,0.78233,NO,16,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,,-3.583,1.648,,,,,,,,,,HHH,,0.221079,0.00245392,0.78233 beta-lactamase_2500_G194L,beta-lactamase_2500_194,TEM-1,beta-lactamase_2500,P62593,0.782337,NO,194,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.396,-3.731,2.335,,0.276,S,b,0.29,0.36,3.593,,67.83,POA,-1.832,0.361275,0.00392163,0.782337 beta-lactamase_2500_K53W,beta-lactamase_2500_53,TEM-1,beta-lactamase_2500,P62593,0.782339,NO,53,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-2.313,-2.612,0.299,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.361275,0.00383383,0.782339 kka2_1:1_V83M,kka2_1:1_83,Kka2,kka2_1:1,P00552,0.782542,NO,83,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-2.567,-3.575,1.008,,0.358,E,B,0.44,0.53,5.931,,71.59,AHH,-2.264,0.520039,0.00650486,0.782542 beta-lactamase_2500_T263Q,beta-lactamase_2500_263,TEM-1,beta-lactamase_2500,P62593,0.782596,NO,263,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.361275,0.0110582,0.782596 beta-lactamase_2500_V101S,beta-lactamase_2500_101,TEM-1,beta-lactamase_2500,P62593,0.7826,NO,101,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.295,-3.65,2.355,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.361275,0.00374492,0.7826 kka2_1:1_F240C,kka2_1:1_240,Kka2,kka2_1:1,P00552,0.782614,NO,240,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-0.911,-4.889,3.978,,,H,A,1.62,-1.21,5.798,,50.38,BHH,-1.67267,0.520039,0.00552543,0.782614 gb1_G235F,gb1_235,gb1,gb1,P06654,0.782621,NO,235,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.419,-3.984,2.565,,,,,,,0.476,,11.83,POB,-1.86433,0.177985,0.00297491,0.782621 kka2_1:8_A237P,kka2_1:8_237,Kka2,kka2_1:8,P00552,0.78266,NO,237,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.12,-4.041,1.921,,0.068,H,A,0.46,-0.71,0.449,,92.05,HHA,-2.10433,0.100394,0.012257,0.78266 kka2_1:8_A237P,kka2_1:8_237,Kka2,kka2_1:8,P00552,0.78266,NO,237,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.12,-4.041,1.921,,0.068,H,A,0.46,-0.71,0.449,,92.05,HHA,-2.10433,0.100394,0.012257,0.78266 beta-lactamase_0_R81G,beta-lactamase_0_81,TEM-1,beta-lactamase_0,P62593,0.782745,NO,81,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.466,-2.66,1.194,,0.218,H,A,1.2,1.66,0.332,,50,PBH,-1.60667,0.0500837,0.00499763,0.782745 kka2_1:1_L67P,kka2_1:1_67,Kka2,kka2_1:1,P00552,0.78283,NO,67,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.741,-4.133,3.392,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.520039,0.00102787,0.78283 kka2_1:4_P98L,kka2_1:4_98,Kka2,kka2_1:4,P00552,0.782879,NO,98,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.526,-3.014,1.488,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.168804,0.00622754,0.782879 kka2_1:8_R258M,kka2_1:8_258,Kka2,kka2_1:8,P00552,0.782883,NO,258,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.626,-3.325,1.699,,0.316,H,A,0.16,-0.85,5.58,,53.03,HBH,-1.25933,0.100394,0.00983174,0.782883 kka2_1:8_R258M,kka2_1:8_258,Kka2,kka2_1:8,P00552,0.782883,NO,258,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.626,-3.325,1.699,,0.316,H,A,0.16,-0.85,5.58,,53.03,HBH,-1.25933,0.100394,0.00983174,0.782883 kka2_1:4_F256L,kka2_1:4_256,Kka2,kka2_1:4,P00552,0.782902,NO,256,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.49,-3.235,1.745,,,H,A,0.58,-0.78,1.653,,53.03,HHH,-1.423,0.168804,0.0132841,0.782902 beta-lactamase_0_Y262S,beta-lactamase_0_262,TEM-1,beta-lactamase_0,P62593,0.78291,NO,262,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.0500837,0.00853516,0.78291 kka2_1:4_A64S,kka2_1:4_64,Kka2,kka2_1:4,P00552,0.782965,NO,64,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.496,-3.437,1.941,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.168804,0.00705578,0.782965 beta-lactamase_0_E108K,beta-lactamase_0_108,TEM-1,beta-lactamase_0,P62593,0.783026,NO,108,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.46,-2.182,0.722,,0.572,G,A,1.04,1.87,8.602,8.602,72.73,PAB,-1.437,0.0500837,0.00413372,0.783026 beta-lactamase_625_V259Y,beta-lactamase_625_259,TEM-1,beta-lactamase_625,P62593,0.783055,NO,259,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.213352,0.0070773,0.783055 beta-lactamase_I256F,beta-lactamase_256,TEM-1,beta-lactamase,P62593,0.783139,NO,256,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.621,-2.76,1.139,5.3196,,E,B,1,-0.84,1.615,,73.08,BHH,-1.80667,0.221079,0.00710634,0.783139 Pab1_S154C,Pab1_154,Pab1,Pab1,P04147,0.783223,NO,154,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.146,-4.454,3.308,,0.208,E,B,0.1,-0.75,,,,HPP,-1.408,0.175299,0.000319331,0.783223 kka2_1:1_L67M,kka2_1:1_67,Kka2,kka2_1:1,P00552,0.783235,NO,67,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.741,-3.833,3.092,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.520039,0.00102787,0.783235 beta-lactamase_N130S,beta-lactamase_130,TEM-1,beta-lactamase,P62593,0.783236,NO,130,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-0.798,-2.936,2.138,5.26686,0.069,H,A,1.08,-0.74,,,,APP,-0.980667,0.221079,0.000683376,0.783236 beta-lactamase_E56Y,beta-lactamase_56,TEM-1,beta-lactamase,P62593,0.783251,NO,56,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.043,-4.216,2.173,5.65281,0.198,E,B,0.52,0.31,2.022,,72.73,HAP,-1.94033,0.221079,0.00238534,0.783251 beta-lactamase_C121L,beta-lactamase_121,TEM-1,beta-lactamase,P62593,0.783305,NO,121,C,L,CL,Special,Hydrophobic,5.07,9.7088,4.6388,198,121,131,10,108.5,166.7,58.2,-0.953,-3.182,2.229,5.12205,,H,A,2.8,-0.81,7.644,,63.29,HOP,-1.46767,0.221079,0.000744322,0.783305 kka2_1:1_T125M,kka2_1:1_125,Kka2,kka2_1:1,P00552,0.783342,NO,125,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.622,-4.759,2.137,,0.791,T,A,0.22,0.33,1.972,,92.05,BPH,-1.56933,0.520039,0.00821755,0.783342 kka2_1:2_D159E,kka2_1:2_159,Kka2,kka2_1:2,P00552,0.783384,NO,159,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.82,-2.917,2.097,,0.28,.,B,0.75,1.25,0.899,,48.11,HAA,-1.48333,0.295029,0.0030485,0.783384 beta-lactamase_0_R59P,beta-lactamase_0_59,TEM-1,beta-lactamase_0,P62593,0.783385,NO,59,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.345,-3.961,2.616,,0.329,S,L,1.2,-0.09,2.919,,73.08,HBO,-2.24267,0.0500837,0.00318082,0.783385 kka2_1:1_L193R,kka2_1:1_193,Kka2,kka2_1:1,P00552,0.783402,NO,193,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.983,-3.937,2.954,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.520039,0.00480179,0.783402 kka2_1:1_P128T,kka2_1:1_128,Kka2,kka2_1:1,P00552,0.783507,NO,128,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.922,-2.576,0.654,,0.316,G,A,0.52,0.4,2.178,,56.06,AOH,-1.64733,0.520039,0.00774689,0.783507 kka2_1:2_G55C,kka2_1:2_55,Kka2,kka2_1:2,P00552,0.783524,NO,55,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.625,-5.134,3.509,,0.517,S,b,0.75,1.19,15.753,15.753,63.64,POH,-2.05967,0.295029,0.00667877,0.783524 kka2_1:1_D154G,kka2_1:1_154,Kka2,kka2_1:1,P00552,0.783594,NO,154,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.876,-3.201,2.325,,0.457,.,b,0.75,1.48,0.658,,52.65,HAP,-1.52467,0.520039,0.00292633,0.783594 kka2_1:2_M116T,kka2_1:2_116,Kka2,kka2_1:2,P00552,0.783603,NO,116,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-2.482,-2.959,0.477,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.295029,0.00745147,0.783603 beta-lactamase_P217W,beta-lactamase_217,TEM-1,beta-lactamase,P62593,0.783604,NO,217,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-2.062,-5.565,3.503,5.19872,0.496,I,A,0.99,-0.33,0.431,,74.48,OOH,-1.64333,0.221079,0.00463211,0.783604 beta-lactamase_2500_D113P,beta-lactamase_2500_113,TEM-1,beta-lactamase_2500,P62593,0.783623,NO,113,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.829,-3.062,1.233,,0.665,T,A,0.75,0.91,21.104,21.104,73.08,PAO,-1.703,0.361275,0.00474112,0.783623 kka2_1:1_R253K,kka2_1:1_253,Kka2,kka2_1:1,P00552,0.783689,NO,253,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.356,-1.563,0.207,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.520039,0.0144195,0.783689 kka2_1:8_E96Y,kka2_1:8_96,Kka2,kka2_1:8,P00552,0.783709,NO,96,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.573,-4.313,1.74,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.100394,0.00369441,0.783709 kka2_1:8_E96Y,kka2_1:8_96,Kka2,kka2_1:8,P00552,0.783709,NO,96,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.573,-4.313,1.74,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.100394,0.00369441,0.783709 beta-lactamase_0_Y262Q,beta-lactamase_0_262,TEM-1,beta-lactamase_0,P62593,0.783723,NO,262,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.0500837,0.00853516,0.783723 kka2_1:4_W24S,kka2_1:4_24,Kka2,kka2_1:4,P00552,0.783724,NO,24,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-1.779,-2.861,1.082,,0.477,E,B,1.51,-0.21,2.666,,56.06,AHH,-2.24467,0.168804,0.00631564,0.783724 beta-lactamase_0_E56N,beta-lactamase_0_56,TEM-1,beta-lactamase_0,P62593,0.783754,NO,56,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.043,-2.542,0.499,,0.198,E,B,1.04,0.31,1.491,,72.73,HAP,-1.94033,0.0500837,0.00238534,0.783754 PSD95pdz3_K380D,PSD95pdz3_380,PSD95pdz3,PSD95pdz3,P31016,0.78378,NO,380,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.416,-3.15,1.734,5.87979,,,,,19.6722,,,,HBP,-1.391,0.0758425,0.000281399,0.78378 gb1_L233K,gb1_233,gb1,gb1,P06654,0.783858,NO,233,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-2.678,-3.276,0.598,,,,,,,0.822,,45.54,HHP,-2.30267,0.177985,0.00266958,0.783858 beta-lactamase_625_L100H,beta-lactamase_625_100,TEM-1,beta-lactamase_625,P62593,0.7839,NO,100,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.218,-4.855,3.637,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.213352,0.00413885,0.7839 beta-lactamase_Y103S,beta-lactamase_103,TEM-1,beta-lactamase,P62593,0.783907,NO,103,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-1.33,-3.594,2.264,5.71734,0.613,S,l,2.55,1.21,5.721,,63.29,AHP,-1.48767,0.221079,0.00443048,0.783907 beta-lactamase_0_T69V,beta-lactamase_0_69,TEM-1,beta-lactamase_0,P62593,0.783946,NO,69,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-0.973,-3.175,2.202,,,G,A,0.22,-1.24,0.505,,93.01,PPH,-1.01833,0.0500837,0.00127498,0.783946 kka2_1:1_A150Q,kka2_1:1_150,Kka2,kka2_1:1,P00552,0.783962,NO,150,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.949,-2.897,1.948,,0.544,T,A,0.46,1.34,2.333,,63.26,AHO,-1.272,0.520039,0.0045009,0.783962 kka2_1:2_Y22M,kka2_1:2_22,Kka2,kka2_1:2,P00552,0.784029,NO,22,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-1.583,-4.724,3.141,,0.122,.,B,0.21,-0.8,1.838,,65.53,OHA,-1.80333,0.295029,0.00598977,0.784029 beta-lactamase_R255M,beta-lactamase_255,TEM-1,beta-lactamase,P62593,0.784119,NO,255,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.266,-4.381,2.115,5.55882,0.141,E,B,0.68,0.38,1.199,,63.99,PBH,-2.00433,0.221079,0.00499612,0.784119 beta-lactamase_T131M,beta-lactamase_131,TEM-1,beta-lactamase,P62593,0.784119,NO,131,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.328,-4.602,3.274,5.0548,,H,A,0.53,-0.69,3.306,,67.48,PPH,-1.00867,0.221079,0.00345886,0.784119 WW_domain_T197S,WW_domain_197,Yap65,WW_domain,P46937,0.78417,NO,197,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.575,-2.998,1.423,6.59907,,,,,,21.052,21.052,70.04,PPP,-1.60267,0.153962,0.00319242,0.78417 kka2_1:4_Q219R,kka2_1:4_219,Kka2,kka2_1:4,P00552,0.784284,NO,219,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-0.93,-2.546,1.616,,0.088,H,A,0.64,-0.85,1.537,,50,HPA,-1.05167,0.168804,0.00237913,0.784284 kka2_1:2_Q219R,kka2_1:2_219,Kka2,kka2_1:2,P00552,0.78429,NO,219,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-0.93,-2.546,1.616,,0.088,H,A,0.4,-0.85,1.917,,50,HPA,-1.05167,0.295029,0.00237913,0.78429 beta-lactamase_I3G,beta-lactamase_3,TEM-1,beta-lactamase,P62593,0.784302,NO,3,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-2.143,-3.463,1.32,,,,,,,3.946,,93.01,PHP,-2.21633,0.221079,0.00349304,0.784302 Pab1_A179I,Pab1_179,Pab1,Pab1,P04147,0.784355,NO,179,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.013,-3.377,2.364,,0.078,H,A,0.61,0.5,,,,HHB,-1.51233,0.175299,0.000291703,0.784355 beta-lactamase_156_I229T,beta-lactamase_156_229,TEM-1,beta-lactamase_156,P62593,0.784447,NO,229,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.267,-2.621,1.354,,0.083,E,B,0.48,-0.76,1.114,,50,HHH,-1.58767,0.111618,0.00477249,0.784447 kka2_1:2_E59L,kka2_1:2_59,Kka2,kka2_1:2,P00552,0.784458,NO,59,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-0.952,-3.625,2.673,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.295029,0.00280355,0.784458 gb1_T244E,gb1_244,gb1,gb1,P06654,0.784474,NO,244,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.637,-3.357,1.72,,,,,,,0.202,,11.83,PPA,-1.92567,0.177985,0.00222755,0.784474 beta-lactamase_625_L100K,beta-lactamase_625_100,TEM-1,beta-lactamase_625,P62593,0.784498,NO,100,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.218,-3.837,2.619,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.213352,0.00413885,0.784498 beta-lactamase_0_L136P,beta-lactamase_0_136,TEM-1,beta-lactamase_0,P62593,0.784516,NO,136,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.232,-4.152,2.92,,,H,A,0.55,-0.34,0.648,,48.95,HHH,-1.088,0.0500837,0.00442304,0.784516 kka2_1:2_G210C,kka2_1:2_210,Kka2,kka2_1:2,P00552,0.784577,NO,210,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.095,-2.875,1.78,,0.103,T,A,0.29,-0.62,0.271,,50,OOB,-0.966667,0.295029,0.00598378,0.784577 kka2_1:2_L7Y,kka2_1:2_7,Kka2,kka2_1:2,P00552,0.784584,NO,7,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.926,-3.823,1.897,,,,,,,3.012,,71.59,OHB,-2.12333,0.295029,0.00269456,0.784584 kka2_1:1_F206C,kka2_1:1_206,Kka2,kka2_1:1,P00552,0.784652,NO,206,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.349,-4.946,3.597,,0.006,E,B,0.58,-1.21,0.978,,63.64,OHH,-1.04,0.520039,0.00936868,0.784652 beta-lactamase_0_S266C,beta-lactamase_0_266,TEM-1,beta-lactamase_0,P62593,0.784667,NO,266,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.0500837,0.0140785,0.784667 beta-lactamase_0_R59E,beta-lactamase_0_59,TEM-1,beta-lactamase_0,P62593,0.784671,NO,59,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.345,-3.322,1.977,,0.329,S,L,1.2,-0.09,2.919,,73.08,HBO,-2.24267,0.0500837,0.00318082,0.784671 beta-lactamase_0_L135T,beta-lactamase_0_135,TEM-1,beta-lactamase_0,P62593,0.784698,NO,135,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.002,-3.475,2.473,,0.117,H,A,0.55,-0.58,0.705,,43.71,PHH,-1.03767,0.0500837,0.00244423,0.784698 kka2_1:8_W69C,kka2_1:8_69,Kka2,kka2_1:8,P00552,0.784724,NO,69,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-0.859,-4.914,4.055,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.100394,0.0012874,0.784724 kka2_1:8_W69C,kka2_1:8_69,Kka2,kka2_1:8,P00552,0.784724,NO,69,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-0.859,-4.914,4.055,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.100394,0.0012874,0.784724 beta-lactamase_0_Y95V,beta-lactamase_0_95,TEM-1,beta-lactamase_0,P62593,0.784753,NO,95,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-1.715,-2.446,0.731,,0.122,,b,0.21,-0.37,2.914,,77.62,BHP,-2.16167,0.0500837,0.00479449,0.784753 beta-lactamase_0_N130L,beta-lactamase_0_130,TEM-1,beta-lactamase_0,P62593,0.784788,NO,130,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-0.798,-3.583,2.785,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.0500837,0.000683376,0.784788 kka2_1:4_W15C,kka2_1:4_15,Kka2,kka2_1:4,P00552,0.784893,NO,15,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-1.392,-4.882,3.49,,0.01,G,A,0.47,0.15,0.943,,52.27,HHH,-2.10533,0.168804,0.00585505,0.784893 beta-lactamase_R91D,beta-lactamase_91,TEM-1,beta-lactamase,P62593,0.784914,NO,91,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.392,-3.521,2.129,5.92536,0.444,,B,0.68,0.96,1.318,,50.35,OBB,-1.73367,0.221079,0.00380226,0.784914 beta-lactamase_L146W,beta-lactamase_146,TEM-1,beta-lactamase,P62593,0.784937,NO,146,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.462,-2.894,1.432,5.62483,0.007,H,A,1.3,-0.56,1.953,,64.69,AHP,-1.656,0.221079,0.00474542,0.784937 kka2_1:4_L103P,kka2_1:4_103,Kka2,kka2_1:4,P00552,0.785006,NO,103,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-2.362,-3.937,1.575,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.168804,0.00574792,0.785006 kka2_1:4_V97Q,kka2_1:4_97,Kka2,kka2_1:4,P00552,0.785019,NO,97,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.453,-4.252,2.799,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.168804,0.00737869,0.785019 beta-lactamase_0_G85V,beta-lactamase_0_85,TEM-1,beta-lactamase_0,P62593,0.785041,NO,85,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.011,-3.796,2.785,,0.805,T,l,0.29,1.7,2.25,,63.64,HOP,-1.68733,0.0500837,0.00252173,0.785041 kka2_1:1_A79T,kka2_1:1_79,Kka2,kka2_1:1,P00552,0.785046,NO,79,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.368,-2.485,0.117,,0.563,.,B,0.46,-0.43,7.792,7.792,71.59,HHH,-1.752,0.520039,0.00664821,0.785046 kka2_1:4_A78S,kka2_1:4_78,Kka2,kka2_1:4,P00552,0.785049,NO,78,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.744,-3.309,1.565,,0.078,.,B,0.46,-0.53,0.594,,56.06,OHH,-1.863,0.168804,0.00457299,0.785049 kka2_1:4_P179N,kka2_1:4_179,Kka2,kka2_1:4,P00552,0.785049,NO,179,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.974,-3.967,2.993,,0.113,,B,0.52,0.69,10.913,10.913,56.06,HOA,-2.19867,0.168804,0.00298346,0.785049 beta-lactamase_T27H,beta-lactamase_27,TEM-1,beta-lactamase,P62593,0.785108,NO,27,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.905,-4.62,2.715,5.39752,0.007,H,A,0.69,-0.37,0.745,,93.01,APH,-1.97933,0.221079,0.00306559,0.785108 beta-lactamase_2500_R81S,beta-lactamase_2500_81,TEM-1,beta-lactamase_2500,P62593,0.785143,NO,81,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.466,-3.386,1.92,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.361275,0.00499763,0.785143 beta-lactamase_2500_S241E,beta-lactamase_2500_241,TEM-1,beta-lactamase_2500,P62593,0.785187,NO,241,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.361275,0.00452736,0.785187 kka2_1:1_P109V,kka2_1:1_109,Kka2,kka2_1:1,P00552,0.785241,NO,109,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.412,-2.937,1.525,,0.376,H,A,0.52,-1.25,18.506,18.506,65.53,HOH,-1.84567,0.520039,0.0070929,0.785241 beta-lactamase_0_L136G,beta-lactamase_0_136,TEM-1,beta-lactamase_0,P62593,0.785276,NO,136,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.232,-3.856,2.624,,,H,A,0.55,-0.34,0.648,,48.95,HHH,-1.088,0.0500837,0.00442304,0.785276 beta-lactamase_156_L192N,beta-lactamase_156_192,TEM-1,beta-lactamase_156,P62593,0.785313,NO,192,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.254,-4.206,2.952,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.111618,0.00558728,0.785313 beta-lactamase_0_I171G,beta-lactamase_0_171,TEM-1,beta-lactamase_0,P62593,0.785345,NO,171,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-2.431,-3.603,1.172,,0.361,,B,0.48,0.53,16.954,16.954,77.62,HHO,-1.55533,0.0500837,0.00623355,0.785345 kka2_1:4_D183F,kka2_1:4_183,Kka2,kka2_1:4,P00552,0.785407,NO,183,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.204,-4.408,3.204,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.168804,0.00426304,0.785407 kka2_1:2_I196R,kka2_1:2_196,Kka2,kka2_1:2,P00552,0.78544,NO,196,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-2.115,-4.247,2.132,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.295029,0.0107273,0.78544 kka2_1:1_C31K,kka2_1:1_31,Kka2,kka2_1:1,P00552,0.785444,NO,31,C,K,CK,Special,PositiveCharge,5.07,9.74,4.67,202,121,146,25,108.5,168.6,60.1,-2.246,-3.377,1.131,,1.152,S,b,0.46,4.16,8.272,,63.26,OOP,-1.21533,0.520039,0.00681582,0.785444 beta-lactamase_156_L167P,beta-lactamase_156_167,TEM-1,beta-lactamase_156,P62593,0.785454,NO,167,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.138,-4.076,2.938,,0.015,G,A,0.55,-0.63,0.4,,64.69,AHP,-1.30767,0.111618,0.00303566,0.785454 beta-lactamase_G142D,beta-lactamase_142,TEM-1,beta-lactamase,P62593,0.785501,NO,142,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.707,-3.466,2.759,4.55474,0.034,,p,0.77,-0.64,1.947,,64.69,OOO,-0.834,0.221079,0.00060149,0.785501 beta-lactamase_R176I,beta-lactamase_176,TEM-1,beta-lactamase,P62593,0.785512,NO,176,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-0.863,-4.01,3.147,5.61264,0.385,T,B,0.68,-0.63,,,,ABA,-1.38867,0.221079,0.00105554,0.785512 kka2_1:1_R122Q,kka2_1:1_122,Kka2,kka2_1:1,P00552,0.785609,NO,122,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.175,-2.893,0.718,,0.487,H,A,1.2,0.26,1.356,,71.59,BBH,-1.53833,0.520039,0.00736512,0.785609 beta-lactamase_V82L,beta-lactamase_82,TEM-1,beta-lactamase,P62593,0.785652,NO,82,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.325,-2.426,1.101,5.27777,0.267,H,A,0.96,0.08,1.379,,93.01,BHA,-1.28567,0.221079,0.00397046,0.785652 beta-lactamase_2500_L73C,beta-lactamase_2500_73,TEM-1,beta-lactamase_2500,P62593,0.785655,NO,73,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.507,-4.861,3.354,,,H,A,0.55,-0.64,2.178,,67.83,HHH,-1.487,0.361275,0.00488983,0.785655 beta-lactamase_V21R,beta-lactamase_21,TEM-1,beta-lactamase,P62593,0.78567,NO,21,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.873,-2.697,0.824,,,,,,,0.688,,93.01,OHH,-2.09633,0.221079,0.0028612,0.78567 beta-lactamase_F70T,beta-lactamase_70,TEM-1,beta-lactamase,P62593,0.785677,NO,70,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.169,-3.571,2.402,5.42055,,H,A,1.1,-1.34,1.14,,63.99,PHB,-0.980667,0.221079,0.00193499,0.785677 PSD95pdz3_V386M,PSD95pdz3_386,PSD95pdz3,PSD95pdz3,P31016,0.785687,NO,386,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.465,-3.712,2.247,5.18836,,,,,17.5429,,,,PHP,-1.463,0.0758425,0.000184509,0.785687 kka2_1:8_P109T,kka2_1:8_109,Kka2,kka2_1:8,P00552,0.785703,NO,109,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.412,-2.893,1.481,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.100394,0.0070929,0.785703 kka2_1:8_P109T,kka2_1:8_109,Kka2,kka2_1:8,P00552,0.785703,NO,109,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.412,-2.893,1.481,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.100394,0.0070929,0.785703 beta-lactamase_H110T,beta-lactamase_110,TEM-1,beta-lactamase,P62593,0.785717,NO,110,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-1.706,-3.697,1.991,5.52635,0.341,G,a,0.35,1.08,31.31,31.31,64.69,BBH,-1.73333,0.221079,0.00441499,0.785717 kka2_1:1_H139P,kka2_1:1_139,Kka2,kka2_1:1,P00552,0.785721,NO,139,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-2.809,-4.177,1.368,,0.471,H,A,0.17,0.68,1.153,,63.64,BBB,-2.22,0.520039,0.00734779,0.785721 kka2_1:4_A64L,kka2_1:4_64,Kka2,kka2_1:4,P00552,0.785796,NO,64,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.496,-2.596,1.1,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.168804,0.00705578,0.785796 kka2_1:1_D5H,kka2_1:1_5,Kka2,kka2_1:1,P00552,0.785852,NO,5,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.306,-4.185,2.879,,,,,,,0.895,,71.59,PAO,-1.784,0.520039,0.00222864,0.785852 beta-lactamase_0_N98E,beta-lactamase_0_98,TEM-1,beta-lactamase_0,P62593,0.785891,NO,98,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-2.973,-2.445,-0.528,,0.963,G,A,0.61,1.35,14.853,14.853,77.62,PPA,-2.07867,0.0500837,0.00505389,0.785891 beta-lactamase_0_T116Y,beta-lactamase_0_116,TEM-1,beta-lactamase_0,P62593,0.785897,NO,116,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.28,-4.295,3.015,,0.115,E,B,0.22,-0.12,1.356,,67.48,HPH,-1.39967,0.0500837,0.00336175,0.785897 kka2_1:8_R38P,kka2_1:8_38,Kka2,kka2_1:8,P00552,0.785924,NO,38,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.207,-4.041,2.834,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.100394,0.00372499,0.785924 kka2_1:8_R38P,kka2_1:8_38,Kka2,kka2_1:8,P00552,0.785924,NO,38,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.207,-4.041,2.834,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.100394,0.00372499,0.785924 beta-lactamase_0_L248P,beta-lactamase_0_248,TEM-1,beta-lactamase_0,P62593,0.785989,NO,248,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.0500837,0.00428493,0.785989 beta-lactamase_A23N,beta-lactamase_23,TEM-1,beta-lactamase,P62593,0.786048,NO,23,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.548,-3.735,2.187,,,,,,,0.801,,93.01,HHB,-2.235,0.221079,0.00245563,0.786048 beta-lactamase_H5F,beta-lactamase_5,TEM-1,beta-lactamase,P62593,0.786048,NO,5,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-2.698,-2.806,0.108,,,,,,,1.865,,72.73,PBH,-2.36967,0.221079,0.00292712,0.786048 beta-lactamase_625_T179C,beta-lactamase_625_179,TEM-1,beta-lactamase_625,P62593,0.786085,NO,179,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.085,-4.712,3.627,,,E,B,0.22,-1.38,0.367,,73.08,PPH,-1.557,0.213352,0.00226045,0.786085 beta-lactamase_0_A282D,beta-lactamase_0_282,TEM-1,beta-lactamase_0,P62593,0.786097,NO,282,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.0500837,0.0449821,0.786097 kka2_1:2_W91R,kka2_1:2_91,Kka2,kka2_1:2,P00552,0.786182,NO,91,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-1.178,-2.437,1.259,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.295029,0.00358653,0.786182 kka2_1:1_Q100R,kka2_1:1_100,Kka2,kka2_1:1,P00552,0.786204,NO,100,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.77,-2.202,-0.568,,0.646,E,B,0.4,-0.79,15.116,15.116,71.59,OPA,-1.46467,0.520039,0.0066405,0.786204 beta-lactamase_0_L248W,beta-lactamase_0_248,TEM-1,beta-lactamase_0,P62593,0.786214,NO,248,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.0500837,0.00428493,0.786214 kka2_1:8_D250Y,kka2_1:8_250,Kka2,kka2_1:8,P00552,0.786239,NO,250,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.015,-4.409,3.394,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.100394,0.0177103,0.786239 kka2_1:8_D250Y,kka2_1:8_250,Kka2,kka2_1:8,P00552,0.786239,NO,250,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.015,-4.409,3.394,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.100394,0.0177103,0.786239 beta-lactamase_625_G281L,beta-lactamase_625_281,TEM-1,beta-lactamase_625,P62593,0.786258,NO,281,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.213352,0.0406482,0.786258 beta-lactamase_0_S266Y,beta-lactamase_0_266,TEM-1,beta-lactamase_0,P62593,0.786344,NO,266,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.0500837,0.0140785,0.786344 kka2_1:8_L19Q,kka2_1:8_19,Kka2,kka2_1:8,P00552,0.786397,NO,19,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.254,-4.298,3.044,,0.08,T,A,1.59,-0.26,2.044,,65.53,BHH,-2.221,0.100394,0.00620703,0.786397 kka2_1:8_L19Q,kka2_1:8_19,Kka2,kka2_1:8,P00552,0.786397,NO,19,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.254,-4.298,3.044,,0.08,T,A,1.59,-0.26,2.044,,65.53,BHH,-2.221,0.100394,0.00620703,0.786397 kka2_1:8_D154Y,kka2_1:8_154,Kka2,kka2_1:8,P00552,0.786428,NO,154,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.876,-4.417,3.541,,0.457,,b,0.29,1.48,0.844,,52.65,HAP,-1.52467,0.100394,0.00292633,0.786428 kka2_1:8_D154Y,kka2_1:8_154,Kka2,kka2_1:8,P00552,0.786428,NO,154,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.876,-4.417,3.541,,0.457,,b,0.29,1.48,0.844,,52.65,HAP,-1.52467,0.100394,0.00292633,0.786428 beta-lactamase_2500_K213G,beta-lactamase_2500_213,TEM-1,beta-lactamase_2500,P62593,0.786489,NO,213,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.81,-2.317,0.507,,0.67,,A,2.34,0.29,1.668,,67.83,ABH,-1.57767,0.361275,0.00610411,0.786489 kka2_1:8_L93P,kka2_1:8_93,Kka2,kka2_1:8,P00552,0.786491,NO,93,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.815,-4.131,3.316,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.100394,0.00131498,0.786491 kka2_1:8_L93P,kka2_1:8_93,Kka2,kka2_1:8,P00552,0.786491,NO,93,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.815,-4.131,3.316,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.100394,0.00131498,0.786491 kka2_1:1_A191L,kka2_1:1_191,Kka2,kka2_1:1,P00552,0.786503,NO,191,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.831,-3.249,2.418,,,.,b,0.46,-0.94,0.53,,50,AHO,-0.868667,0.520039,0.00338807,0.786503 kka2_1:4_R258H,kka2_1:4_258,Kka2,kka2_1:4,P00552,0.78654,NO,258,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.626,-4.623,2.997,,0.316,H,A,1.2,-0.85,2.655,,53.03,HBH,-1.25933,0.168804,0.00983174,0.78654 beta-lactamase_156_W227A,beta-lactamase_156_227,TEM-1,beta-lactamase_156,P62593,0.786542,NO,227,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-0.982,-3.46,2.478,,0.272,,B,0.47,-0.29,2.533,,74.48,OHH,-1.595,0.111618,0.00226019,0.786542 kka2_1:4_P132A,kka2_1:4_132,Kka2,kka2_1:4,P00552,0.786678,NO,132,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.775,-3.073,2.298,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.168804,0.0018489,0.786678 beta-lactamase_P105A,beta-lactamase_105,TEM-1,beta-lactamase,P62593,0.786701,NO,105,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.813,-3.041,2.228,5.08236,0.226,T,A,0.98,0.8,1.154,,63.29,POH,-1.01533,0.221079,0.0011981,0.786701 PSD95pdz3_F325S,PSD95pdz3_325,PSD95pdz3,PSD95pdz3,P31016,0.786722,NO,325,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.524,-3.292,1.768,5.50654,,,,,12.7236,,,,OHP,-1.314,0.0758425,0.00102273,0.786722 kka2_1:4_A119V,kka2_1:4_119,Kka2,kka2_1:4,P00552,0.786724,NO,119,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.073,-2.406,1.333,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.168804,0.00441074,0.786724 beta-lactamase_2500_L55H,beta-lactamase_2500_55,TEM-1,beta-lactamase_2500,P62593,0.786779,NO,55,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.86,-4.855,2.995,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.361275,0.00403741,0.786779 beta-lactamase_2500_A170T,beta-lactamase_2500_170,TEM-1,beta-lactamase_2500,P62593,0.786793,NO,170,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.237,-3.423,2.186,,0.126,,L,0.46,-0.35,2.427,,64.69,AHH,-1.63267,0.361275,0.00431903,0.786793 beta-lactamase_2500_W163G,beta-lactamase_2500_163,TEM-1,beta-lactamase_2500,P62593,0.786798,NO,163,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-1.843,-2.648,0.805,,0.467,,B,0.47,-0.5,32.624,32.624,63.99,BHA,-1.269,0.361275,0.00418955,0.786798 beta-lactamase_2500_L28F,beta-lactamase_2500_28,TEM-1,beta-lactamase_2500,P62593,0.786899,NO,28,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.579,-3.916,2.337,,0.277,H,A,0.55,-0.16,2.716,,93.01,PHH,-2.11333,0.361275,0.00359321,0.786899 gb1_A249E,gb1_249,gb1,gb1,P06654,0.786912,NO,249,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.739,-3.374,1.635,,,,,,,0.252,,44.87,AHH,-1.67367,0.177985,0.00333585,0.786912 kka2_1:2_R140S,kka2_1:2_140,Kka2,kka2_1:2,P00552,0.786918,NO,140,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.351,-2.551,1.2,,0.12,H,A,1.2,0.2,0.352,,53.03,BBH,-1.885,0.295029,0.00430167,0.786918 beta-lactamase_0_A133D,beta-lactamase_0_133,TEM-1,beta-lactamase_0,P62593,0.786948,NO,133,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.186,-3.675,2.489,,,H,A,0.46,-0.86,2.148,,67.83,HHP,-0.988333,0.0500837,0.00468022,0.786948 beta-lactamase_0_V82P,beta-lactamase_0_82,TEM-1,beta-lactamase_0,P62593,0.786967,NO,82,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.325,-4.008,2.683,,0.267,H,A,0.44,0.08,1.893,,93.01,BHA,-1.28567,0.0500837,0.00397046,0.786967 beta-lactamase_0_A40T,beta-lactamase_0_40,TEM-1,beta-lactamase_0,P62593,0.787003,NO,40,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.402,-2.653,1.251,,0.155,S,B,0.46,0.21,0.783,,73.78,OHB,-1.40267,0.0500837,0.00490026,0.787003 kka2_1:4_L232P,kka2_1:4_232,Kka2,kka2_1:4,P00552,0.787082,NO,232,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.514,-4.306,2.792,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.168804,0.00800103,0.787082 Pab1_L186Q,Pab1_186,Pab1,Pab1,P04147,0.787148,NO,186,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.783,-4.139,2.356,,,,,,,,,,HHP,-1.56967,0.175299,0.00154968,0.787148 beta-lactamase_R162M,beta-lactamase_162,TEM-1,beta-lactamase,P62593,0.787158,NO,162,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.016,-4.454,3.438,5.34456,0.124,S,B,0.68,-0.37,31.656,31.656,64.69,ABH,-1.25,0.221079,0.000561334,0.787158 beta-lactamase_S264M,beta-lactamase_264,TEM-1,beta-lactamase,P62593,0.787158,NO,264,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.985,-3.36,1.375,4.67475,0.04,,B,0.25,0.29,34.251,34.251,73.78,OPP,-2.19867,0.221079,0.0119399,0.787158 kka2_1:2_K138F,kka2_1:2_138,Kka2,kka2_1:2,P00552,0.787211,NO,138,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-2.5,-4.458,1.958,,0.594,H,A,2.34,0.98,21.038,21.038,71.59,HBB,-2.48833,0.295029,0.00628542,0.787211 PSD95pdz3_I316P,PSD95pdz3_316,PSD95pdz3,PSD95pdz3,P31016,0.787214,NO,316,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.63,-3.786,2.156,5.46166,,,,,19.005,,,,HHB,-1.62733,0.0758425,0.00112762,0.787214 kka2_1:8_L60H,kka2_1:8_60,Kka2,kka2_1:8,P00552,0.787215,NO,60,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.997,-4.966,3.969,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.100394,0.00262176,0.787215 kka2_1:8_L60H,kka2_1:8_60,Kka2,kka2_1:8,P00552,0.787215,NO,60,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.997,-4.966,3.969,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.100394,0.00262176,0.787215 kka2_1:1_D238H,kka2_1:1_238,Kka2,kka2_1:1,P00552,0.787229,NO,238,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.83,-4.728,1.898,,0.604,H,A,0.75,-0.33,11.329,11.329,92.05,HAB,-2.633,0.520039,0.0113863,0.787229 WW_domain_G176C,WW_domain_176,Yap65,WW_domain,P46937,0.787244,NO,176,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.235,-4.781,3.546,6.33142,,,,,,2.71,,78.57,HOH,-1.35467,0.153962,0.00288552,0.787244 kka2_1:4_T51F,kka2_1:4_51,Kka2,kka2_1:4,P00552,0.787257,NO,51,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.199,-4.265,2.066,,0.05,E,B,0.82,-0.05,13.165,13.165,63.64,BPA,-1.76767,0.168804,0.00628861,0.787257 beta-lactamase_2500_M153G,beta-lactamase_2500_153,TEM-1,beta-lactamase_2500,P62593,0.787275,NO,153,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-3.193,-3.633,0.44,,0.14,T,A,0.55,-0.11,3.409,,77.62,PHO,-2.25767,0.361275,0.00509109,0.787275 kka2_1:4_V214M,kka2_1:4_214,Kka2,kka2_1:4,P00552,0.787292,NO,214,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.261,-4.2,2.939,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.168804,0.00692782,0.787292 beta-lactamase_A235L,beta-lactamase_235,TEM-1,beta-lactamase,P62593,0.787324,NO,235,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.266,-3.325,2.059,4.83024,0.32,E,B,0.52,-0.86,1.344,,50,OHO,-0.89,0.221079,0.00493474,0.787324 kka2_1:4_P132V,kka2_1:4_132,Kka2,kka2_1:4,P00552,0.787334,NO,132,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.775,-3.58,2.805,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.168804,0.0018489,0.787334 beta-lactamase_0_L79W,beta-lactamase_0_79,TEM-1,beta-lactamase_0,P62593,0.787375,NO,79,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.842,-5.095,4.253,,0.007,H,A,0.55,-0.16,5.053,,50.35,HHP,-1.44333,0.0500837,0.000947397,0.787375 beta-lactamase_P165H,beta-lactamase_165,TEM-1,beta-lactamase,P62593,0.787385,NO,165,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.373,-4.751,3.378,5.33889,0.203,T,A,0.99,-0.31,0.414,,73.78,AOA,-1.359,0.221079,0.00549538,0.787385 kka2_1:1_F256Y,kka2_1:1_256,Kka2,kka2_1:1,P00552,0.787484,NO,256,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.49,-1.474,-0.016,,,H,A,1.62,-0.78,2.354,,53.03,HHH,-1.423,0.520039,0.0132841,0.787484 beta-lactamase_156_V117E,beta-lactamase_156_117,TEM-1,beta-lactamase_156,P62593,0.787491,NO,117,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.53,-3.909,2.379,,,H,A,0.44,-0.34,1.182,,65.03,PHB,-1.741,0.111618,0.00467906,0.787491 gb1_E282R,gb1_282,gb1,gb1,P06654,0.787516,NO,282,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.318,-3.382,2.064,,,,,,,1.075,,35.71,PAO,-1.573,0.177985,0.00209643,0.787516 gb1_L233G,gb1_233,gb1,gb1,P06654,0.787516,NO,233,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-2.678,-3.405,0.727,,,,,,,0.822,,45.54,HHP,-2.30267,0.177985,0.00266958,0.787516 kka2_1:4_D156V,kka2_1:4_156,Kka2,kka2_1:4,P00552,0.787546,NO,156,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.696,-3.632,1.936,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.168804,0.00926998,0.787546 beta-lactamase_0_P165W,beta-lactamase_0_165,TEM-1,beta-lactamase_0,P62593,0.787572,NO,165,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.373,-5.352,3.979,,0.203,T,A,0.52,-0.31,3.242,,73.78,AOA,-1.359,0.0500837,0.00549538,0.787572 hsp90_W585Y,hsp90_585,hsp90,hsp90,P02829,0.787645,NO,585,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-4.251,-3.316,0,5.31455,0.508,,B,1.22,0.43,,,,OHP,-3.17533,0.368192,0.000222939,0.787645 beta-lactamase_0_R63K,beta-lactamase_0_63,TEM-1,beta-lactamase_0,P62593,0.787683,NO,63,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-0.943,-2.877,1.934,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.0500837,0.00126938,0.787683 beta-lactamase_D161Q,beta-lactamase_161,TEM-1,beta-lactamase,P62593,0.787703,NO,161,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.891,-3.667,2.776,5.12208,0.341,,A,0.23,-0.52,1.602,,61.19,HAB,-0.961333,0.221079,0.000897697,0.787703 beta-lactamase_2500_P255E,beta-lactamase_2500_255,TEM-1,beta-lactamase_2500,P62593,0.787747,NO,255,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.361275,0.00499612,0.787747 kka2_1:2_T28N,kka2_1:2_28,Kka2,kka2_1:2,P00552,0.787774,NO,28,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.883,-3.817,1.934,,0.353,S,B,0.22,2.02,2.655,,63.64,PPH,-1.74467,0.295029,0.00743084,0.787774 beta-lactamase_0_L55W,beta-lactamase_0_55,TEM-1,beta-lactamase_0,P62593,0.787782,NO,55,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.86,-2.099,0.239,,0.372,E,A,0.55,-0.36,1.967,,63.99,HHA,-2.247,0.0500837,0.00403741,0.787782 beta-lactamase_R91F,beta-lactamase_91,TEM-1,beta-lactamase,P62593,0.787793,NO,91,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.392,-4.376,2.984,5.92536,0.444,,B,0.68,0.96,1.318,,50.35,OBB,-1.73367,0.221079,0.00380226,0.787793 beta-lactamase_156_A246F,beta-lactamase_156_246,TEM-1,beta-lactamase_156,P62593,0.787808,NO,246,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.121,-2.727,0.606,,0.01,E,B,0.46,-1.01,1.959,,73.78,HHH,-1.55633,0.111618,0.00569458,0.787808 WW_domain_W177F,WW_domain_177,Yap65,WW_domain,P46937,0.78783,NO,177,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-1.198,-3.169,1.971,5.18137,,,,,,,,,OHA,-1.197,0.153962,0.00198549,0.78783 beta-lactamase_0_L74Q,beta-lactamase_0_74,TEM-1,beta-lactamase_0,P62593,0.787831,NO,74,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.296,-4.107,2.811,,,H,A,0.55,-0.91,1.46,,50,HHO,-1.34933,0.0500837,0.00493255,0.787831 kka2_1:2_V46F,kka2_1:2_46,Kka2,kka2_1:2,P00552,0.787841,NO,46,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-2.62,-3.464,0.844,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.295029,0.00631301,0.787841 kka2_1:4_R143F,kka2_1:4_143,Kka2,kka2_1:4,P00552,0.787844,NO,143,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.525,-4.3,1.775,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.168804,0.00662247,0.787844 beta-lactamase_0_G90D,beta-lactamase_0_90,TEM-1,beta-lactamase_0,P62593,0.787852,NO,90,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-2.091,-2.02,-0.071,,0.598,T,A,0.29,0.32,2.04,,77.62,HOB,-1.52633,0.0500837,0.00490273,0.787852 kka2_1:1_H188Q,kka2_1:1_188,Kka2,kka2_1:1,P00552,0.787881,NO,188,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-0.913,-2.723,1.81,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.520039,0.00273139,0.787881 kka2_1:2_F264L,kka2_1:2_264,Kka2,kka2_1:2,P00552,0.787981,NO,264,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.02,-2.468,1.448,,0.296,.,?,0.58,0.02,2.303,,71.59,HHNA,-0.9655,0.295029,,0.787981 beta-lactamase_2500_S96C,beta-lactamase_2500_96,TEM-1,beta-lactamase_2500,P62593,0.788022,NO,96,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.27,-5.145,2.875,,0.368,,b,0.27,0.39,32.348,32.348,73.78,HPP,-2.019,0.361275,0.00551835,0.788022 beta-lactamase_S104H,beta-lactamase_104,TEM-1,beta-lactamase,P62593,0.788047,NO,104,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.015,-4.582,3.567,4.92365,0.04,,b,0.82,0.57,4.02,,63.29,HPO,-1.05267,0.221079,0.00218083,0.788047 beta-lactamase_2500_P255D,beta-lactamase_2500_255,TEM-1,beta-lactamase_2500,P62593,0.788054,NO,255,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.361275,0.00499612,0.788054 kka2_1:8_F256T,kka2_1:8_256,Kka2,kka2_1:8,P00552,0.788062,NO,256,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.49,-3.783,2.293,,,H,A,1.62,-0.78,1.713,,53.03,HHH,-1.423,0.100394,0.0132841,0.788062 kka2_1:8_F256T,kka2_1:8_256,Kka2,kka2_1:8,P00552,0.788062,NO,256,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.49,-3.783,2.293,,,H,A,1.62,-0.78,1.713,,53.03,HHH,-1.423,0.100394,0.0132841,0.788062 beta-lactamase_0_A40S,beta-lactamase_0_40,TEM-1,beta-lactamase_0,P62593,0.788073,NO,40,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.402,-3.164,1.762,,0.155,S,B,0.46,0.21,0.783,,73.78,OHB,-1.40267,0.0500837,0.00490026,0.788073 PSD95pdz3_I388H,PSD95pdz3_388,PSD95pdz3,PSD95pdz3,P31016,0.788124,NO,388,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.63,-4.587,2.957,5.17282,,,,,16.0025,,,,PHH,-1.54967,0.0758425,0.000151216,0.788124 beta-lactamase_L197V,beta-lactamase_197,TEM-1,beta-lactamase,P62593,0.788152,NO,197,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.853,-2.903,2.05,5.19172,0.007,S,B,1.3,0.33,1.756,,60.14,HHP,-1.833,0.221079,0.00144602,0.788152 kka2_1:4_E161L,kka2_1:4_161,Kka2,kka2_1:4,P00552,0.788169,NO,161,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.581,-3.558,1.977,,0.829,G,A,1.52,2.24,1.612,,92.05,AAB,-1.861,0.168804,0.00760103,0.788169 Pab1_I128A,Pab1_128,Pab1,Pab1,P04147,0.788199,NO,128,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.345,-2.891,1.546,,0.008,E,B,1.68,-0.6,1.706,,78.68,PHH,-1.231,0.175299,0.00104192,0.788199 beta-lactamase_L120A,beta-lactamase_120,TEM-1,beta-lactamase,P62593,0.788203,NO,120,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.044,-3.203,2.159,5.11974,,H,A,1.3,-1.13,1.988,,64.69,AHO,-1.13633,0.221079,0.00143563,0.788203 beta-lactamase_2500_P255T,beta-lactamase_2500_255,TEM-1,beta-lactamase_2500,P62593,0.788237,NO,255,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.361275,0.00499612,0.788237 kka2_1:2_S32R,kka2_1:2_32,Kka2,kka2_1:2,P00552,0.788246,NO,32,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-0.804,-3.736,2.932,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.295029,0.00149998,0.788246 beta-lactamase_R159L,beta-lactamase_159,TEM-1,beta-lactamase,P62593,0.788261,NO,159,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-0.94,-3.407,2.467,5.64971,0.316,,B,0.68,-0.55,1.172,,64.34,PBH,-1.011,0.221079,0.00108472,0.788261 beta-lactamase_0_P143D,beta-lactamase_0_143,TEM-1,beta-lactamase_0,P62593,0.788262,NO,143,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.967,-3.622,2.655,,0.075,H,A,0.52,-0.37,11.868,11.868,66.78,OOB,-1.354,0.0500837,0.00114551,0.788262 beta-lactamase_0_K71Y,beta-lactamase_0_71,TEM-1,beta-lactamase_0,P62593,0.788383,NO,71,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-0.8,-4.162,3.362,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.0500837,0.00103192,0.788383 beta-lactamase_R59A,beta-lactamase_59,TEM-1,beta-lactamase,P62593,0.788619,NO,59,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.345,-3.163,1.818,5.49837,0.329,S,L,0.68,-0.09,1.806,,73.08,HBO,-2.24267,0.221079,0.00318082,0.788619 beta-lactamase_0_T27E,beta-lactamase_0_27,TEM-1,beta-lactamase_0,P62593,0.788625,NO,27,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.905,-2.714,0.809,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.0500837,0.00306559,0.788625 kka2_1:8_W91L,kka2_1:8_91,Kka2,kka2_1:8,P00552,0.788625,NO,91,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-1.178,-3.365,2.187,,0.077,E,B,1.51,0.27,2.51,,48.48,AHH,-1.51,0.100394,0.00358653,0.788625 kka2_1:8_W91L,kka2_1:8_91,Kka2,kka2_1:8,P00552,0.788625,NO,91,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-1.178,-3.365,2.187,,0.077,E,B,1.51,0.27,2.51,,48.48,AHH,-1.51,0.100394,0.00358653,0.788625 beta-lactamase_0_L135D,beta-lactamase_0_135,TEM-1,beta-lactamase_0,P62593,0.788651,NO,135,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.002,-4.125,3.123,,0.117,H,A,0.55,-0.58,0.705,,43.71,PHH,-1.03767,0.0500837,0.00244423,0.788651 kka2_1:4_L184P,kka2_1:4_184,Kka2,kka2_1:4,P00552,0.788672,NO,184,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.496,-2.724,1.228,,0.489,E,B,1.59,-0.06,4.495,,63.26,AHH,-1.24833,0.168804,0.00518742,0.788672 kka2_1:2_L107P,kka2_1:2_107,Kka2,kka2_1:2,P00552,0.788677,NO,107,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.238,-4.14,2.902,,0.197,,B,1.59,-1.1,2.68,,71.59,BHH,-2.143,0.295029,0.00561937,0.788677 beta-lactamase_0_E26A,beta-lactamase_0_26,TEM-1,beta-lactamase_0,P62593,0.788687,NO,26,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.454,-2.207,-0.247,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.0500837,0.00297948,0.788687 beta-lactamase_0_R176K,beta-lactamase_0_176,TEM-1,beta-lactamase_0,P62593,0.788692,NO,176,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-0.863,-2.782,1.919,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.0500837,0.00105554,0.788692 kka2_1:8_P109Q,kka2_1:8_109,Kka2,kka2_1:8,P00552,0.788719,NO,109,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.412,-3.143,1.731,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.100394,0.0070929,0.788719 kka2_1:8_P109Q,kka2_1:8_109,Kka2,kka2_1:8,P00552,0.788719,NO,109,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.412,-3.143,1.731,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.100394,0.0070929,0.788719 beta-lactamase_V21F,beta-lactamase_21,TEM-1,beta-lactamase,P62593,0.788752,NO,21,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.873,-4.023,2.15,,,,,,,0.688,,93.01,OHH,-2.09633,0.221079,0.0028612,0.788752 kka2_1:2_N200K,kka2_1:2_200,Kka2,kka2_1:2,P00552,0.788752,NO,200,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-2.446,-2.694,0.248,,0.756,T,L,0.61,-0.08,2.836,,64.39,APO,-2.08,0.295029,0.00838549,0.788752 beta-lactamase_0_W288E,beta-lactamase_0_288,TEM-1,beta-lactamase_0,P62593,0.788753,NO,288,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,,,,,,,,,,,,,BHO,,0.0500837,,0.788753 beta-lactamase_2500_G141N,beta-lactamase_2500_141,TEM-1,beta-lactamase_2500,P62593,0.788768,NO,141,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.828,-3.472,2.644,,0.575,T,l,0.29,-0.28,1.493,,64.69,HOO,-1.08933,0.361275,0.0012419,0.788768 kka2_1:8_S32L,kka2_1:8_32,Kka2,kka2_1:8,P00552,0.788781,NO,32,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-0.804,-3.386,2.582,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.100394,0.00149998,0.788781 kka2_1:8_S32L,kka2_1:8_32,Kka2,kka2_1:8,P00552,0.788781,NO,32,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-0.804,-3.386,2.582,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.100394,0.00149998,0.788781 kka2_1:4_G95M,kka2_1:4_95,Kka2,kka2_1:4,P00552,0.788787,NO,95,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-2.403,-4.756,2.353,,0.126,E,B,0.29,-0.74,0.359,,71.59,HOA,-2.198,0.168804,0.00743616,0.788787 beta-lactamase_G154M,beta-lactamase_154,TEM-1,beta-lactamase,P62593,0.788867,NO,154,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.823,-4.936,4.113,5.40944,0.54,T,l,0.77,-0.56,2.283,,64.69,HOA,-1.635,0.221079,0.00180205,0.788867 beta-lactamase_R159Y,beta-lactamase_159,TEM-1,beta-lactamase,P62593,0.788867,NO,159,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-0.94,-4.035,3.095,5.64971,0.316,,B,0.68,-0.55,1.172,,64.34,PBH,-1.011,0.221079,0.00108472,0.788867 beta-lactamase_0_D174I,beta-lactamase_0_174,TEM-1,beta-lactamase_0,P62593,0.788886,NO,174,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.738,-4.01,3.272,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.0500837,0.00125633,0.788886 beta-lactamase_2500_M127H,beta-lactamase_2500_127,TEM-1,beta-lactamase_2500,P62593,0.78891,NO,127,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-2.251,-4.786,2.535,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.361275,0.00437927,0.78891 kka2_1:8_T51D,kka2_1:8_51,Kka2,kka2_1:8,P00552,0.78891,NO,51,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.199,-3.85,1.651,,0.05,E,B,0.82,-0.05,5.399,,63.64,BPA,-1.76767,0.100394,0.00628861,0.78891 kka2_1:8_T51D,kka2_1:8_51,Kka2,kka2_1:8,P00552,0.78891,NO,51,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.199,-3.85,1.651,,0.05,E,B,0.82,-0.05,5.399,,63.64,BPA,-1.76767,0.100394,0.00628861,0.78891 beta-lactamase_W208Y,beta-lactamase_208,TEM-1,beta-lactamase,P62593,0.788964,NO,208,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-0.818,-3.262,2.444,5.26277,0.067,H,A,0.99,-0.65,,,,AHH,-1.44133,0.221079,0.00126609,0.788964 kka2_1:2_R89S,kka2_1:2_89,Kka2,kka2_1:2,P00552,0.788972,NO,89,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.548,-3.512,1.964,,0.209,E,B,1.2,1.41,14.396,14.396,64.39,OBA,-1.89867,0.295029,0.00524373,0.788972 beta-lactamase_2500_D174E,beta-lactamase_2500_174,TEM-1,beta-lactamase_2500,P62593,0.789051,NO,174,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.738,-2.765,2.027,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.361275,0.00125633,0.789051 beta-lactamase_0_I229Y,beta-lactamase_0_229,TEM-1,beta-lactamase_0,P62593,0.789124,NO,229,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.267,-4.04,2.773,,0.083,E,B,0.48,-0.76,1.69,,50,HHH,-1.58767,0.0500837,0.00477249,0.789124 kka2_1:4_R147S,kka2_1:4_147,Kka2,kka2_1:4,P00552,0.789139,NO,147,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.123,-3.438,2.315,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.168804,0.00549168,0.789139 kka2_1:1_Y22C,kka2_1:1_22,Kka2,kka2_1:1,P00552,0.789204,NO,22,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-1.583,-3.399,1.816,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.520039,0.00598977,0.789204 beta-lactamase_L47S,beta-lactamase_47,TEM-1,beta-lactamase,P62593,0.789227,NO,47,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.876,-3.642,1.766,5.27297,0.007,E,B,1.07,0.2,1.244,,67.83,AHA,-1.639,0.221079,0.00439844,0.789227 kka2_1:1_H188P,kka2_1:1_188,Kka2,kka2_1:1,P00552,0.789288,NO,188,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-0.913,-3.906,2.993,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.520039,0.00273139,0.789288 beta-lactamase_0_M209K,beta-lactamase_0_209,TEM-1,beta-lactamase_0,P62593,0.78929,NO,209,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.442,-3.673,2.231,,,H,A,0.55,-0.97,3.876,,64.69,HHA,-1.52633,0.0500837,0.00625021,0.78929 gb1_G235W,gb1_235,gb1,gb1,P06654,0.789314,NO,235,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.419,-4.908,3.489,,,,,,,0.476,,11.83,POB,-1.86433,0.177985,0.00297491,0.789314 beta-lactamase_625_D231C,beta-lactamase_625_231,TEM-1,beta-lactamase_625,P62593,0.789333,NO,231,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.816,-5.136,4.32,,,E,B,0.75,-1.06,1.025,,65.38,HAB,-0.994,0.213352,0.00107395,0.789333 kka2_1:1_P45R,kka2_1:1_45,Kka2,kka2_1:1,P00552,0.78938,NO,45,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.774,-3.184,1.41,,0.669,.,B,0.52,-0.76,4.882,,71.59,BOH,-2.152,0.520039,0.00590481,0.78938 beta-lactamase_0_I125L,beta-lactamase_0_125,TEM-1,beta-lactamase_0,P62593,0.789389,NO,125,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.441,-1.939,0.498,,,H,A,0.48,-0.7,1.874,,63.29,HHP,-1.248,0.0500837,0.00383964,0.789389 beta-lactamase_39_R59I,beta-lactamase_39_59,TEM-1,beta-lactamase_39,P62593,0.789491,NO,59,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.345,-4.065,2.72,,0.329,S,L,1.2,-0.09,1.806,,73.08,HBO,-2.24267,0.0495842,0.00318082,0.789491 beta-lactamase_G141R,beta-lactamase_141,TEM-1,beta-lactamase,P62593,0.789516,NO,141,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.828,-3.94,3.112,5.03155,0.575,T,l,0.76,-0.28,0.198,,64.69,HOO,-1.08933,0.221079,0.0012419,0.789516 beta-lactamase_A246W,beta-lactamase_246,TEM-1,beta-lactamase,P62593,0.789573,NO,246,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.121,-5.267,3.146,4.78979,0.01,E,B,0.52,-1.01,1.26,,73.78,HHH,-1.55633,0.221079,0.00569458,0.789573 beta-lactamase_E87S,beta-lactamase_87,TEM-1,beta-lactamase,P62593,0.789614,NO,87,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.421,-3.382,1.961,5.41929,0.048,,B,0.52,0.92,1.754,,64.69,PAP,-1.969,0.221079,0.00337888,0.789614 kka2_1:8_D33Y,kka2_1:8_33,Kka2,kka2_1:8,P00552,0.789656,NO,33,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.186,-4.503,2.317,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.100394,0.00633568,0.789656 kka2_1:8_D33Y,kka2_1:8_33,Kka2,kka2_1:8,P00552,0.789656,NO,33,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.186,-4.503,2.317,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.100394,0.00633568,0.789656 Pab1_L153I,Pab1_153,Pab1,Pab1,P04147,0.789677,NO,153,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.039,-2.702,1.663,,0.46,E,A,,-0.95,,,,HHP,-1.17667,0.175299,0.000321212,0.789677 beta-lactamase_0_V31Q,beta-lactamase_0_31,TEM-1,beta-lactamase_0,P62593,0.789685,NO,31,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.822,-4.296,2.474,,,H,A,0.44,-0.46,4.126,,73.78,BHB,-2.03767,0.0500837,0.00478065,0.789685 beta-lactamase_0_L284W,beta-lactamase_0_284,TEM-1,beta-lactamase_0,P62593,0.78969,NO,284,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.981,,,,0.848,H,A,2.89,0.67,4.544,,77.62,PHH,-1.82133,0.0500837,0.0686156,0.78969 beta-lactamase_0_I229K,beta-lactamase_0_229,TEM-1,beta-lactamase_0,P62593,0.789696,NO,229,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.267,-3.862,2.595,,0.083,E,B,0.48,-0.76,1.69,,50,HHH,-1.58767,0.0500837,0.00477249,0.789696 beta-lactamase_0_L191A,beta-lactamase_0_191,TEM-1,beta-lactamase_0,P62593,0.789786,NO,191,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.087,-2.236,1.149,,,H,A,0.55,0.09,12.255,12.255,63.29,BHH,-1.445,0.0500837,0.00263549,0.789786 PSD95pdz3_G364P,PSD95pdz3_364,PSD95pdz3,PSD95pdz3,P31016,0.789806,NO,364,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.008,-3.561,2.553,5.53299,,,,,21.28,,,,POH,-1.33667,0.0758425,0.00050942,0.789806 kka2_1:8_M120W,kka2_1:8_120,Kka2,kka2_1:8,P00552,0.789809,NO,120,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-3.877,-5.169,1.292,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.100394,0.00265808,0.789809 kka2_1:8_M120W,kka2_1:8_120,Kka2,kka2_1:8,P00552,0.789809,NO,120,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-3.877,-5.169,1.292,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.100394,0.00265808,0.789809 kka2_1:1_P132T,kka2_1:1_132,Kka2,kka2_1:1,P00552,0.789812,NO,132,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.775,-3.417,2.642,,0.692,.,A,0.52,0.56,0.224,,44.7,OOH,-0.825667,0.520039,0.0018489,0.789812 beta-lactamase_156_L188N,beta-lactamase_156_188,TEM-1,beta-lactamase_156,P62593,0.789925,NO,188,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.166,-4.122,2.956,,,H,A,0.55,-0.3,1.574,,60.14,PHB,-1.47033,0.111618,0.00295687,0.789925 kka2_1:8_D190Y,kka2_1:8_190,Kka2,kka2_1:8,P00552,0.789936,NO,190,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.708,-4.416,3.708,,0.213,S,b,0.29,-0.82,,,,OAH,-0.711667,0.100394,0.00247989,0.789936 kka2_1:8_D190Y,kka2_1:8_190,Kka2,kka2_1:8,P00552,0.789936,NO,190,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.708,-4.416,3.708,,0.213,S,b,0.29,-0.82,,,,OAH,-0.711667,0.100394,0.00247989,0.789936 kka2_1:8_H124N,kka2_1:8_124,Kka2,kka2_1:8,P00552,0.789967,NO,124,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-0.84,-3.251,2.411,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.100394,0.00211296,0.789967 kka2_1:8_H124N,kka2_1:8_124,Kka2,kka2_1:8,P00552,0.789967,NO,124,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-0.84,-3.251,2.411,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.100394,0.00211296,0.789967 kka2_1:1_L19R,kka2_1:1_19,Kka2,kka2_1:1,P00552,0.790042,NO,19,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.254,-4.143,2.889,,0.08,T,A,0.55,-0.26,17.165,17.165,65.53,BHH,-2.221,0.520039,0.00620703,0.790042 beta-lactamase_0_P165Y,beta-lactamase_0_165,TEM-1,beta-lactamase_0,P62593,0.79006,NO,165,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.373,-4.331,2.958,,0.203,T,A,0.52,-0.31,3.242,,73.78,AOA,-1.359,0.0500837,0.00549538,0.79006 kka2_1:2_R258L,kka2_1:2_258,Kka2,kka2_1:2,P00552,0.790062,NO,258,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.626,-2.791,1.165,,0.316,H,A,1.2,-0.85,7.485,7.485,53.03,HBH,-1.25933,0.295029,0.00983174,0.790062 beta-lactamase_625_P143E,beta-lactamase_625_143,TEM-1,beta-lactamase_625,P62593,0.790068,NO,143,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.967,-3.58,2.613,,0.075,H,A,0.52,-0.37,1.445,,66.78,OOB,-1.354,0.213352,0.00114551,0.790068 beta-lactamase_0_P224L,beta-lactamase_0_224,TEM-1,beta-lactamase_0,P62593,0.79009,NO,224,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.893,-3.582,2.689,,0.383,,B,0.52,-0.3,3.587,,74.48,HOH,-1.26433,0.0500837,0.00189564,0.79009 kka2_1:4_P128Q,kka2_1:4_128,Kka2,kka2_1:4,P00552,0.790092,NO,128,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.922,-4.314,2.392,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.168804,0.00774689,0.790092 kka2_1:1_G55R,kka2_1:1_55,Kka2,kka2_1:1,P00552,0.790112,NO,55,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.625,-4.045,2.42,,0.517,S,b,0.29,1.19,4.035,,63.64,POH,-2.05967,0.520039,0.00667877,0.790112 beta-lactamase_A9E,beta-lactamase_9,TEM-1,beta-lactamase,P62593,0.79012,NO,9,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.147,-3.721,1.574,,,,,,,5.128,,72.73,HHH,-2.04267,0.221079,0.00247263,0.79012 beta-lactamase_C18L,beta-lactamase_18,TEM-1,beta-lactamase,P62593,0.79012,NO,18,C,L,CL,Special,Hydrophobic,5.07,9.7088,4.6388,198,121,131,10,108.5,166.7,58.2,-2.26,-3.419,1.159,,,,,,,3.995,,93.01,HOH,-2.093,0.221079,0.002536,0.79012 beta-lactamase_Y103M,beta-lactamase_103,TEM-1,beta-lactamase,P62593,0.79012,NO,103,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-1.33,-4.627,3.297,5.71734,0.613,S,l,2.55,1.21,5.721,,63.29,AHP,-1.48767,0.221079,0.00443048,0.79012 PSD95pdz3_G344I,PSD95pdz3_344,PSD95pdz3,PSD95pdz3,P31016,0.790124,NO,344,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.008,-3.917,2.909,4.83855,,,,,14.06,,,,HOO,-1.10767,0.0758425,0.00078498,0.790124 beta-lactamase_0_Y262C,beta-lactamase_0_262,TEM-1,beta-lactamase_0,P62593,0.790171,NO,262,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.0500837,0.00853516,0.790171 beta-lactamase_L38R,beta-lactamase_38,TEM-1,beta-lactamase,P62593,0.79019,NO,38,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.343,-4.054,2.711,5.23728,0.088,H,A,1.75,0.2,1.986,,64.34,PHO,-1.78033,0.221079,0.00373244,0.79019 kka2_1:1_G245C,kka2_1:1_245,Kka2,kka2_1:1,P00552,0.790262,NO,245,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.812,-5.118,4.306,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.520039,0.00683899,0.790262 hsp90_N588G,hsp90_588,hsp90,hsp90,P02829,0.790316,NO,588,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-3.051,-2.511,0,4.61142,0.019,H,A,0.14,0.39,,,,HPH,-3.12167,0.368192,0.000222939,0.790316 Ubiquitin_I23G,Ubiquitin_23,Uba1,Ubiquitin,P0CG48,0.790323,NO,23,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.325,-3.743,2.418,4.67534,,H,A,0.01,-0.93,0.515,,52.12,PHA,-1.54033,0.205827,0.000621252,0.790323 Ubiquitin_V70L,Ubiquitin_70,Uba1,Ubiquitin,P0CG48,0.790323,NO,70,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.874,-2.46,0.586,5.29728,0.05,E,B,0.96,-0.97,2.363,,34.31,HHH,-1.65533,0.205827,0.00106871,0.790323 beta-lactamase_0_E35Y,beta-lactamase_0_35,TEM-1,beta-lactamase_0,P62593,0.790369,NO,35,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-0.869,-4.211,3.342,,0.15,H,A,1.04,0.21,0.664,,46.85,HAA,-1.88667,0.0500837,0.00174441,0.790369 beta-lactamase_0_V31R,beta-lactamase_0_31,TEM-1,beta-lactamase_0,P62593,0.790474,NO,31,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.822,-4.173,2.351,,,H,A,0.44,-0.46,4.126,,73.78,BHB,-2.03767,0.0500837,0.00478065,0.790474 PSD95pdz3_L353W,PSD95pdz3_353,PSD95pdz3,PSD95pdz3,P31016,0.790486,NO,353,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.347,-4.779,3.432,5.81136,,,,,17.3525,,,,AHB,-1.50533,0.0758425,0.000664742,0.790486 beta-lactamase_0_V101N,beta-lactamase_0_101,TEM-1,beta-lactamase_0,P62593,0.790496,NO,101,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.295,-4.085,2.79,,0.342,,B,0.44,0,1.61,,73.08,HHA,-1.54367,0.0500837,0.00374492,0.790496 beta-lactamase_0_L137A,beta-lactamase_0_137,TEM-1,beta-lactamase_0,P62593,0.79051,NO,137,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.03,-3.142,2.112,,,H,A,0.55,-0.38,0.328,,42.31,HHP,-1.58933,0.0500837,0.00278599,0.79051 beta-lactamase_2500_G194Y,beta-lactamase_2500_194,TEM-1,beta-lactamase_2500,P62593,0.79056,NO,194,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.396,-4.427,3.031,,0.276,S,b,0.29,0.36,3.593,,67.83,POA,-1.832,0.361275,0.00392163,0.79056 WW_domain_T182S,WW_domain_182,Yap65,WW_domain,P46937,0.790628,NO,182,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.149,-2.713,1.564,6.20597,,,,,,,,,BPP,-1.483,0.153962,0.00294574,0.790628 kka2_1:4_P109N,kka2_1:4_109,Kka2,kka2_1:4,P00552,0.790681,NO,109,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.412,-3.924,2.512,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.168804,0.0070929,0.790681 kka2_1:1_K112E,kka2_1:1_112,Kka2,kka2_1:1,P00552,0.790708,NO,112,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-2.491,-3.666,1.175,,0.076,H,A,2.34,-1.37,23.433,23.433,56.06,ABH,-2.00133,0.520039,0.00645389,0.790708 beta-lactamase_0_P60W,beta-lactamase_0_60,TEM-1,beta-lactamase_0,P62593,0.790753,NO,60,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-2.469,-5.456,2.987,,0.256,T,A,0.52,-0.56,3.653,,77.62,BOA,-1.97633,0.0500837,0.00521318,0.790753 beta-lactamase_625_L248F,beta-lactamase_625_248,TEM-1,beta-lactamase_625,P62593,0.79083,NO,248,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.213352,0.00428493,0.79083 beta-lactamase_R41C,beta-lactamase_41,TEM-1,beta-lactamase,P62593,0.790877,NO,41,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-0.942,-5.05,4.108,5.69185,0.321,E,B,0.91,-0.07,4.357,,65.03,HBH,-1.30267,0.221079,0.00123327,0.790877 beta-lactamase_P105H,beta-lactamase_105,TEM-1,beta-lactamase,P62593,0.790885,NO,105,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.813,-4.678,3.865,5.08236,0.226,T,A,0.98,0.8,1.154,,63.29,POH,-1.01533,0.221079,0.0011981,0.790885 beta-lactamase_0_K53I,beta-lactamase_0_53,TEM-1,beta-lactamase_0,P62593,0.790962,NO,53,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-2.313,-4.015,1.702,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.0500837,0.00383383,0.790962 kka2_1:1_V49A,kka2_1:1_49,Kka2,kka2_1:1,P00552,0.790985,NO,49,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.614,-2.584,0.97,,,E,B,0.44,-0.77,3.665,3.665,64.39,HHB,-1.3,0.520039,0.00615685,0.790985 kka2_1:8_L193A,kka2_1:8_193,Kka2,kka2_1:8,P00552,0.791061,NO,193,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.983,-3.189,2.206,,,G,A,1.59,-1.03,2.234,,65.53,OHO,-0.965333,0.100394,0.00480179,0.791061 kka2_1:8_L193A,kka2_1:8_193,Kka2,kka2_1:8,P00552,0.791061,NO,193,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.983,-3.189,2.206,,,G,A,1.59,-1.03,2.234,,65.53,OHO,-0.965333,0.100394,0.00480179,0.791061 gb1_G240W,gb1_240,gb1,gb1,P06654,0.791092,NO,240,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.921,-4.833,3.912,,,,,,,,,,BOA,-1.87867,0.177985,0.00270792,0.791092 beta-lactamase_2500_F228A,beta-lactamase_2500_228,TEM-1,beta-lactamase_2500,P62593,0.791128,NO,228,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-2.342,-2.562,0.22,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.361275,0.0046669,0.791128 beta-lactamase_R220K,beta-lactamase_220,TEM-1,beta-lactamase,P62593,0.791191,NO,220,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-0.942,-2.865,1.923,5.65995,0.295,I,A,0.68,-0.76,2.164,,74.48,HBP,-1.33633,0.221079,0.00232421,0.791191 beta-lactamase_625_D99C,beta-lactamase_625_99,TEM-1,beta-lactamase_625,P62593,0.791207,NO,99,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.191,-5.117,3.926,,0.402,G,A,0.75,0.36,1.318,,64.69,PAH,-1.794,0.213352,0.00305446,0.791207 beta-lactamase_0_L111D,beta-lactamase_0_111,TEM-1,beta-lactamase_0,P62593,0.791216,NO,111,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.76,-3.995,2.235,,0.328,T,A,0.55,0.93,1.966,,64.34,BHP,-1.884,0.0500837,0.00480671,0.791216 beta-lactamase_0_P143C,beta-lactamase_0_143,TEM-1,beta-lactamase_0,P62593,0.791245,NO,143,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.967,-5.012,4.045,,0.075,H,A,0.52,-0.37,11.868,11.868,66.78,OOB,-1.354,0.0500837,0.00114551,0.791245 beta-lactamase_0_I229Q,beta-lactamase_0_229,TEM-1,beta-lactamase_0,P62593,0.791249,NO,229,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.267,-4.304,3.037,,0.083,E,B,0.48,-0.76,1.69,,50,HHH,-1.58767,0.0500837,0.00477249,0.791249 kka2_1:8_D183T,kka2_1:8_183,Kka2,kka2_1:8,P00552,0.791261,NO,183,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.204,-3.525,2.321,,0.518,.,b,0.75,0.25,0.347,,52.27,AAH,-1.40533,0.100394,0.00426304,0.791261 kka2_1:8_D183T,kka2_1:8_183,Kka2,kka2_1:8,P00552,0.791261,NO,183,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.204,-3.525,2.321,,0.518,.,b,0.75,0.25,0.347,,52.27,AAH,-1.40533,0.100394,0.00426304,0.791261 beta-lactamase_156_K53P,beta-lactamase_156_53,TEM-1,beta-lactamase_156,P62593,0.791286,NO,53,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-2.313,-3.069,0.756,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.111618,0.00383383,0.791286 kka2_1:2_E169S,kka2_1:2_169,Kka2,kka2_1:2,P00552,0.791319,NO,169,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.996,-2.626,0.63,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.295029,0.00730086,0.791319 beta-lactamase_G226W,beta-lactamase_226,TEM-1,beta-lactamase,P62593,0.791335,NO,226,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.461,-5.464,4.003,5.70682,0.701,T,l,0.77,-0.25,3.199,,74.48,HOH,-1.42933,0.221079,0.00665294,0.791335 kka2_1:1_F48L,kka2_1:1_48,Kka2,kka2_1:1,P00552,0.791367,NO,48,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.453,-2.543,1.09,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.520039,0.00475422,0.791367 beta-lactamase_R63E,beta-lactamase_63,TEM-1,beta-lactamase,P62593,0.791423,NO,63,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-0.943,-3.298,2.355,5.49979,0.218,,B,0.45,-0.31,0.677,,44.06,ABH,-0.992333,0.221079,0.00126938,0.791423 beta-lactamase_0_G39D,beta-lactamase_0_39,TEM-1,beta-lactamase_0,P62593,0.791428,NO,39,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.864,-2.194,0.33,,0.701,T,L,0.29,0.47,4.111,,77.62,HOH,-1.53633,0.0500837,0.00487611,0.791428 beta-lactamase_L89T,beta-lactamase_89,TEM-1,beta-lactamase,P62593,0.791542,NO,89,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.096,-3.474,2.378,5.41092,0.168,T,A,1.75,0.63,1.599,,64.34,PHO,-1.75767,0.221079,0.00207068,0.791542 beta-lactamase_0_S68E,beta-lactamase_0_68,TEM-1,beta-lactamase_0,P62593,0.791545,NO,68,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-0.913,-3.241,2.328,,0.064,G,A,0.27,-1.03,1.441,,64.69,HPP,-1.37233,0.0500837,0.000800065,0.791545 beta-lactamase_F149D,beta-lactamase_149,TEM-1,beta-lactamase,P62593,0.791552,NO,149,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.299,-3.957,2.658,5.54789,0.195,H,A,1.1,0.11,1.863,,63.99,HHH,-1.46067,0.221079,0.00418462,0.791552 beta-lactamase_0_D83R,beta-lactamase_0_83,TEM-1,beta-lactamase_0,P62593,0.791569,NO,83,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.066,-3.889,2.823,,0.354,H,A,0.75,0.22,0.617,,48.95,HAH,-1.34733,0.0500837,0.00205968,0.791569 beta-lactamase_C75F,beta-lactamase_75,TEM-1,beta-lactamase,P62593,0.791601,NO,75,C,F,CF,Special,Hydrophobic,5.07,3.32051,-1.74949,205,121,165,44,108.5,189.9,81.4,-1.245,-4.17,2.925,4.88171,,H,A,0.25,-0.87,0.876,,50,HOO,-1.24333,0.221079,0.0034616,0.791601 beta-lactamase_2500_P250M,beta-lactamase_2500_250,TEM-1,beta-lactamase_2500,P62593,0.791776,NO,250,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.361275,0.00550899,0.791776 kka2_1:2_L94I,kka2_1:2_94,Kka2,kka2_1:2,P00552,0.791785,NO,94,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.618,-2.284,0.666,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.295029,0.00520888,0.791785 kka2_1:2_A64K,kka2_1:2_64,Kka2,kka2_1:2,P00552,0.791846,NO,64,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.496,-3.777,2.281,,0.039,H,A,0.46,-0.57,14.509,14.509,56.06,AHH,-1.334,0.295029,0.00705578,0.791846 beta-lactamase_R241S,beta-lactamase_241,TEM-1,beta-lactamase,P62593,0.791879,NO,241,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.433,-3.314,1.881,5.02621,0.094,E,B,0.68,-0.16,1.327,,50,PBO,-1.42967,0.221079,0.00452736,0.791879 Pab1_E176F,Pab1_176,Pab1,Pab1,P04147,0.791888,NO,176,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.003,-4.263,2.26,,,,,,,,,,AAO,-2.09933,0.175299,0.00264426,0.791888 kka2_1:4_P128H,kka2_1:4_128,Kka2,kka2_1:4,P00552,0.791961,NO,128,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.922,-4.964,3.042,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.168804,0.00774689,0.791961 beta-lactamase_2500_G216S,beta-lactamase_2500_216,TEM-1,beta-lactamase_2500,P62593,0.792071,NO,216,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.477,-3.283,1.806,,0.437,I,A,0.29,-0.58,1.983,,74.48,HOO,-1.68067,0.361275,0.00639568,0.792071 beta-lactamase_0_M153N,beta-lactamase_0_153,TEM-1,beta-lactamase_0,P62593,0.79224,NO,153,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-3.193,-3.994,0.801,,0.14,T,A,0.55,-0.11,3.826,,77.62,PHO,-2.25767,0.0500837,0.00509109,0.79224 gb1_N263V,gb1_263,gb1,gb1,P06654,0.792266,NO,263,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-1.162,-3.531,2.369,,,,,,,,,,APO,-2.04233,0.177985,0.0035297,0.792266 beta-lactamase_0_L197E,beta-lactamase_0_197,TEM-1,beta-lactamase_0,P62593,0.792301,NO,197,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.853,-3.853,3,,0.007,S,B,0.55,0.33,1.087,,60.14,HHP,-1.833,0.0500837,0.00144602,0.792301 Pab1_E181F,Pab1_181,Pab1,Pab1,P04147,0.792334,NO,181,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.767,-4.138,2.371,,,,,,,1.395,,73.83,BAH,-1.575,0.175299,0.00107557,0.792334 kka2_1:8_W236L,kka2_1:8_236,Kka2,kka2_1:8,P00552,0.792388,NO,236,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-1.363,-2.199,0.836,,0.303,H,A,1.51,-0.76,1.87,,48.48,AHH,-1.81267,0.100394,0.0088796,0.792388 kka2_1:8_W236L,kka2_1:8_236,Kka2,kka2_1:8,P00552,0.792388,NO,236,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-1.363,-2.199,0.836,,0.303,H,A,1.51,-0.76,1.87,,48.48,AHH,-1.81267,0.100394,0.0088796,0.792388 Pab1_D138Y,Pab1_138,Pab1,Pab1,P04147,0.792432,NO,138,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.128,-4.198,3.07,,0.427,,B,,-0.03,,,,HAP,-1.13967,0.175299,0.000567877,0.792432 kka2_1:1_V16E,kka2_1:1_16,Kka2,kka2_1:1,P00552,0.792434,NO,16,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-3.087,-2.983,-0.104,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.520039,0.00694011,0.792434 beta-lactamase_0_L111Y,beta-lactamase_0_111,TEM-1,beta-lactamase_0,P62593,0.792439,NO,111,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.76,-4.039,2.279,,0.328,T,A,0.55,0.93,1.966,,64.34,BHP,-1.884,0.0500837,0.00480671,0.792439 beta-lactamase_M268D,beta-lactamase_268,TEM-1,beta-lactamase,P62593,0.792447,NO,268,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-2.023,-4.044,2.021,5.4797,0.471,H,A,0.09,0.3,1.071,,65.73,PHA,-2.16233,0.221079,0.0102525,0.792447 beta-lactamase_0_M66N,beta-lactamase_0_66,TEM-1,beta-lactamase_0,P62593,0.792463,NO,66,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.362,-4.083,2.721,,0.013,,A,0.55,-0.7,1.204,,73.08,OHH,-1.49567,0.0500837,0.00412876,0.792463 beta-lactamase_L137S,beta-lactamase_137,TEM-1,beta-lactamase,P62593,0.792468,NO,137,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.03,-3.64,2.61,5.20117,,H,A,1.07,-0.38,0.674,,42.31,HHP,-1.58933,0.221079,0.00278599,0.792468 Pab1_T159H,Pab1_159,Pab1,Pab1,P04147,0.792499,NO,159,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.445,-4.511,3.066,,,,,,,2.531,,79.03,HPA,-1.19467,0.175299,0.00133849,0.792499 beta-lactamase_0_V82E,beta-lactamase_0_82,TEM-1,beta-lactamase_0,P62593,0.792504,NO,82,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.325,-3.751,2.426,,0.267,H,A,0.44,0.08,1.893,,93.01,BHA,-1.28567,0.0500837,0.00397046,0.792504 beta-lactamase_0_L137E,beta-lactamase_0_137,TEM-1,beta-lactamase_0,P62593,0.792545,NO,137,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.03,-3.919,2.889,,,H,A,0.55,-0.38,0.328,,42.31,HHP,-1.58933,0.0500837,0.00278599,0.792545 kka2_1:4_V214T,kka2_1:4_214,Kka2,kka2_1:4,P00552,0.792551,NO,214,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.261,-3.47,2.209,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.168804,0.00692782,0.792551 hsp90_E590R,hsp90_590,hsp90,hsp90,P02829,0.792576,NO,590,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.818,-3.086,0,4.65049,0.021,H,A,,0.03,,,,HAO,-3.338,0.368192,0.000222939,0.792576 beta-lactamase_2500_D99K,beta-lactamase_2500_99,TEM-1,beta-lactamase_2500,P62593,0.792591,NO,99,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.191,-3.447,2.256,,0.402,G,A,0.75,0.36,1.318,,64.69,PAH,-1.794,0.361275,0.00305446,0.792591 kka2_1:2_D154H,kka2_1:2_154,Kka2,kka2_1:2,P00552,0.792619,NO,154,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.876,-4.446,3.57,,0.457,,b,0.29,1.48,3.631,,52.65,HAP,-1.52467,0.295029,0.00292633,0.792619 beta-lactamase_0_G249Q,beta-lactamase_0_249,TEM-1,beta-lactamase_0,P62593,0.792622,NO,249,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.0500837,0.00220169,0.792622 beta-lactamase_T116I,beta-lactamase_116,TEM-1,beta-lactamase,P62593,0.792626,NO,116,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.28,-3.822,2.542,4.78335,0.115,E,B,0.69,-0.12,0.343,,67.48,HPH,-1.39967,0.221079,0.00336175,0.792626 beta-lactamase_0_N130Y,beta-lactamase_0_130,TEM-1,beta-lactamase_0,P62593,0.792658,NO,130,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-0.798,-4.162,3.364,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.0500837,0.000683376,0.792658 beta-lactamase_0_L191H,beta-lactamase_0_191,TEM-1,beta-lactamase_0,P62593,0.79266,NO,191,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.087,-4.898,3.811,,,H,A,0.55,0.09,12.255,12.255,63.29,BHH,-1.445,0.0500837,0.00263549,0.79266 kka2_1:8_D261Y,kka2_1:8_261,Kka2,kka2_1:8,P00552,0.792666,NO,261,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.708,-4.416,3.708,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.100394,0.0224846,0.792666 kka2_1:8_D261Y,kka2_1:8_261,Kka2,kka2_1:8,P00552,0.792666,NO,261,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.708,-4.416,3.708,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.100394,0.0224846,0.792666 WW_domain_W177Y,WW_domain_177,Yap65,WW_domain,P46937,0.792717,NO,177,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-1.198,-3.039,1.841,5.18137,,,,,,,,,OHA,-1.197,0.153962,0.00198549,0.792717 beta-lactamase_2500_V101A,beta-lactamase_2500_101,TEM-1,beta-lactamase_2500,P62593,0.792745,NO,101,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.295,-3.114,1.819,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.361275,0.00374492,0.792745 beta-lactamase_G52Q,beta-lactamase_52,TEM-1,beta-lactamase,P62593,0.792747,NO,52,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.149,-2.995,1.846,5.12093,0.299,,l,0.77,-0.04,2.103,,64.69,POB,-1.66267,0.221079,0.00340138,0.792747 beta-lactamase_S201Q,beta-lactamase_201,TEM-1,beta-lactamase,P62593,0.792747,NO,201,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.183,-2.836,1.653,4.85496,0.064,H,A,0.77,-0.07,4.045,,64.69,HPB,-1.451,0.221079,0.00198815,0.792747 beta-lactamase_R91E,beta-lactamase_91,TEM-1,beta-lactamase,P62593,0.792779,NO,91,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.392,-2.211,0.819,5.92536,0.444,,B,0.68,0.96,1.318,,50.35,OBB,-1.73367,0.221079,0.00380226,0.792779 kka2_1:2_W236G,kka2_1:2_236,Kka2,kka2_1:2,P00552,0.79279,NO,236,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-1.363,-2.755,1.392,,0.303,H,A,1.51,-0.76,5.58,,48.48,AHH,-1.81267,0.295029,0.0088796,0.79279 beta-lactamase_P224N,beta-lactamase_224,TEM-1,beta-lactamase,P62593,0.792829,NO,224,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.893,-3.802,2.909,5.179,0.383,,B,0.99,-0.3,0.383,,74.48,HOH,-1.26433,0.221079,0.00189564,0.792829 Pab1_I128N,Pab1_128,Pab1,Pab1,P04147,0.79283,NO,128,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.345,-4.016,2.671,,0.008,E,B,1.68,-0.6,1.706,,78.68,PHH,-1.231,0.175299,0.00104192,0.79283 kka2_1:4_V214K,kka2_1:4_214,Kka2,kka2_1:4,P00552,0.792864,NO,214,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.261,-3.816,2.555,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.168804,0.00692782,0.792864 beta-lactamase_0_A170R,beta-lactamase_0_170,TEM-1,beta-lactamase_0,P62593,0.79287,NO,170,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.237,-3.908,2.671,,0.126,,L,0.46,-0.35,2.427,,64.69,AHH,-1.63267,0.0500837,0.00431903,0.79287 beta-lactamase_2500_R81F,beta-lactamase_2500_81,TEM-1,beta-lactamase_2500,P62593,0.792892,NO,81,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.466,-4.359,2.893,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.361275,0.00499763,0.792892 beta-lactamase_0_K53W,beta-lactamase_0_53,TEM-1,beta-lactamase_0,P62593,0.792913,NO,53,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-2.313,-2.612,0.299,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.0500837,0.00383383,0.792913 beta-lactamase_2500_R239I,beta-lactamase_2500_239,TEM-1,beta-lactamase_2500,P62593,0.792921,NO,239,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.361275,0.00213852,0.792921 beta-lactamase_0_D129G,beta-lactamase_0_129,TEM-1,beta-lactamase_0,P62593,0.792929,NO,129,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.816,-3.182,2.366,,,,B,0.75,-0.69,2.66,,34.97,PAP,-0.818,0.0500837,0.00109178,0.792929 beta-lactamase_L10N,beta-lactamase_10,TEM-1,beta-lactamase,P62593,0.792953,NO,10,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.623,-3.943,2.32,,,,,,,2.467,,65.38,HHH,-1.83833,0.221079,0.00296968,0.792953 beta-lactamase_V257A,beta-lactamase_257,TEM-1,beta-lactamase,P62593,0.792953,NO,257,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.533,-1.879,0.346,5.31999,,E,B,0.96,-0.7,1.463,,58.74,HHH,-1.70967,0.221079,0.00756629,0.792953 kka2_1:1_R140S,kka2_1:1_140,Kka2,kka2_1:1,P00552,0.792967,NO,140,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.351,-2.551,1.2,,0.12,H,A,1.2,0.2,11.345,11.345,53.03,BBH,-1.885,0.520039,0.00430167,0.792967 kka2_1:8_L67A,kka2_1:8_67,Kka2,kka2_1:8,P00552,0.793098,NO,67,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.741,-3.106,2.365,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.100394,0.00102787,0.793098 kka2_1:8_L67A,kka2_1:8_67,Kka2,kka2_1:8,P00552,0.793098,NO,67,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.741,-3.106,2.365,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.100394,0.00102787,0.793098 kka2_1:1_V242C,kka2_1:1_242,Kka2,kka2_1:1,P00552,0.793115,NO,242,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-2.687,-5.161,2.474,,0.75,H,A,0.44,-0.37,4.987,,71.59,HHH,-2.16533,0.520039,0.0102575,0.793115 beta-lactamase_N168M,beta-lactamase_168,TEM-1,beta-lactamase,P62593,0.79312,NO,168,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-1.029,-4.683,3.654,5.42128,0.113,G,A,0.09,-0.4,1.211,,44.41,HPA,-1.13233,0.221079,0.00288667,0.79312 PSD95pdz3_G356D,PSD95pdz3_356,PSD95pdz3,PSD95pdz3,P31016,0.793159,NO,356,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.008,-3.15,2.142,4.8656,,,,,11.9575,,,,BOA,-1.22933,0.0758425,0.000623061,0.793159 beta-lactamase_2500_L137V,beta-lactamase_2500_137,TEM-1,beta-lactamase_2500,P62593,0.793182,NO,137,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.03,-2.816,1.786,,,H,A,0.55,-0.38,0.769,,42.31,HHP,-1.58933,0.361275,0.00278599,0.793182 beta-lactamase_0_L188Y,beta-lactamase_0_188,TEM-1,beta-lactamase_0,P62593,0.793185,NO,188,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.166,-3.998,2.832,,,H,A,0.55,-0.3,2.739,,60.14,PHB,-1.47033,0.0500837,0.00295687,0.793185 beta-lactamase_39_F64H,beta-lactamase_39_64,TEM-1,beta-lactamase_39,P62593,0.793218,NO,64,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-0.841,-4.455,3.614,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.0495842,0.000947691,0.793218 beta-lactamase_0_S233N,beta-lactamase_0_233,TEM-1,beta-lactamase_0,P62593,0.793279,NO,233,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.886,-2.73,0.844,,0.016,E,B,0.27,-1.01,3.579,,77.62,BPO,-1.17267,0.0500837,0.00311415,0.793279 beta-lactamase_625_A40E,beta-lactamase_625_40,TEM-1,beta-lactamase_625,P62593,0.793331,NO,40,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.402,-3.641,2.239,,0.155,S,B,0.46,0.21,1.357,,73.78,OHB,-1.40267,0.213352,0.00490026,0.793331 beta-lactamase_P105K,beta-lactamase_105,TEM-1,beta-lactamase,P62593,0.793378,NO,105,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.813,-3.454,2.641,5.08236,0.226,T,A,0.98,0.8,1.154,,63.29,POH,-1.01533,0.221079,0.0011981,0.793378 beta-lactamase_0_G154K,beta-lactamase_0_154,TEM-1,beta-lactamase_0,P62593,0.79342,NO,154,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.823,-3.683,2.86,,0.54,T,l,0.29,-0.56,3.629,,64.69,HOA,-1.635,0.0500837,0.00180205,0.79342 gb1_T244D,gb1_244,gb1,gb1,P06654,0.793432,NO,244,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.637,-3.48,1.843,,,,,,,0.202,,11.83,PPA,-1.92567,0.177985,0.00222755,0.793432 gb1_Y229S,gb1_229,gb1,gb1,P06654,0.793432,NO,229,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-1.282,-3.346,2.064,,,,,,,,,,PHB,-1.4915,0.177985,0.00366605,0.793432 gb1_Y271M,gb1_271,gb1,gb1,P06654,0.793432,NO,271,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-1.181,-4.257,3.076,,,,,,,,,,PHA,-1.92933,0.177985,0.00236544,0.793432 kka2_1:8_F133V,kka2_1:8_133,Kka2,kka2_1:8,P00552,0.793437,NO,133,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-0.871,-3.355,2.484,,0.178,,B,1.62,0.43,1.816,,42.42,OHA,-0.871667,0.100394,0.00182168,0.793437 kka2_1:8_F133V,kka2_1:8_133,Kka2,kka2_1:8,P00552,0.793437,NO,133,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-0.871,-3.355,2.484,,0.178,,B,1.62,0.43,1.816,,42.42,OHA,-0.871667,0.100394,0.00182168,0.793437 kka2_1:1_C31R,kka2_1:1_31,Kka2,kka2_1:1,P00552,0.793453,NO,31,C,R,CR,Special,PositiveCharge,5.07,6.34148,1.27148,180,121,174,53,108.5,173.4,64.9,-2.246,-1.901,-0.345,,1.152,S,b,0.46,4.16,8.272,,63.26,OOP,-1.21533,0.520039,0.00681582,0.793453 kka2_1:2_V16W,kka2_1:2_16,Kka2,kka2_1:2,P00552,0.793455,NO,16,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-3.087,-5.53,2.443,,0.742,T,A,0.44,0.34,1.746,,71.59,HHA,-2.211,0.295029,0.00694011,0.793455 kka2_1:4_F206C,kka2_1:4_206,Kka2,kka2_1:4,P00552,0.793502,NO,206,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.349,-4.946,3.597,,0.006,E,B,0.58,-1.21,1.342,,63.64,OHH,-1.04,0.168804,0.00936868,0.793502 PSD95pdz3_F337D,PSD95pdz3_337,PSD95pdz3,PSD95pdz3,P31016,0.793502,NO,337,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.524,-3.6,2.076,5.22838,,,,,13.4936,,,,HHH,-1.59467,0.0758425,0.000875287,0.793502 beta-lactamase_0_I285F,beta-lactamase_0_285,TEM-1,beta-lactamase_0,P62593,0.793506,NO,285,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.0500837,0.101555,0.793506 beta-lactamase_0_R81S,beta-lactamase_0_81,TEM-1,beta-lactamase_0,P62593,0.793566,NO,81,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.466,-3.386,1.92,,0.218,H,A,1.2,1.66,0.332,,50,PBH,-1.60667,0.0500837,0.00499763,0.793566 beta-lactamase_156_D174F,beta-lactamase_156_174,TEM-1,beta-lactamase_156,P62593,0.793616,NO,174,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.738,-4.292,3.554,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.111618,0.00125633,0.793616 beta-lactamase_D155N,beta-lactamase_155,TEM-1,beta-lactamase,P62593,0.793642,NO,155,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.889,-2.502,1.613,4.92265,0.049,,B,0.45,-0.9,3.208,,64.69,OAB,-1.62267,0.221079,0.00135315,0.793642 hsp90_S586G,hsp90_586,hsp90,hsp90,P02829,0.793702,NO,586,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.764,-2.511,0,4.65438,,,B,0.93,0.15,,,,HPH,-3.157,0.368192,0.000222939,0.793702 kka2_1:2_L241M,kka2_1:2_241,Kka2,kka2_1:2,P00552,0.793709,NO,241,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.158,-4.084,2.926,,0.08,H,A,0.55,-0.82,1.598,,63.26,HHH,-1.58533,0.295029,0.0117299,0.793709 kka2_1:1_M197R,kka2_1:1_197,Kka2,kka2_1:1,P00552,0.793712,NO,197,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.707,-4.083,2.376,,0.121,E,B,1.59,-1.19,2.097,,65.53,HHH,-1.847,0.520039,0.00921295,0.793712 kka2_1:2_L92Q,kka2_1:2_92,Kka2,kka2_1:2,P00552,0.79373,NO,92,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.893,-4.159,3.266,,0.007,E,B,1.59,-0.19,1.447,,63.26,HHH,-0.962,0.295029,0.00307177,0.79373 kka2_1:1_L126M,kka2_1:1_126,Kka2,kka2_1:1,P00552,0.793755,NO,126,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.246,-4.129,2.883,,0.285,S,B,0.55,0.12,0.302,,51.89,PHA,-1.744,0.520039,0.0066485,0.793755 kka2_1:1_A13V,kka2_1:1_13,Kka2,kka2_1:1,P00552,0.793778,NO,13,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.248,-2.845,0.597,,0.689,G,A,0.46,0.99,25.015,25.015,92.05,OHH,-1.646,0.520039,0.00784241,0.793778 beta-lactamase_0_L150W,beta-lactamase_0_150,TEM-1,beta-lactamase_0,P62593,0.793779,NO,150,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.326,-5.247,3.921,,,H,A,0.55,-0.2,2.128,,62.94,HHB,-1.86167,0.0500837,0.00463171,0.793779 PSD95pdz3_L323I,PSD95pdz3_323,PSD95pdz3,PSD95pdz3,P31016,0.793795,NO,323,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.347,-2.567,1.22,5.12397,,,,,13.8825,,,,OHO,-1.121,0.0758425,0.00104644,0.793795 beta-lactamase_L135E,beta-lactamase_135,TEM-1,beta-lactamase,P62593,0.793814,NO,135,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.002,-3.919,2.917,5.28497,0.117,H,A,1.07,-0.58,0.697,,43.71,PHH,-1.03767,0.221079,0.00244423,0.793814 kka2_1:2_R145S,kka2_1:2_145,Kka2,kka2_1:2,P00552,0.793822,NO,145,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.804,-2.769,0.965,,0.346,H,A,1.2,1.23,7.961,,63.64,HBP,-1.88033,0.295029,0.00846663,0.793822 kka2_1:2_G181I,kka2_1:2_181,Kka2,kka2_1:2,P00552,0.793844,NO,181,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-2.698,-3.104,0.406,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.295029,0.00728319,0.793844 hsp90_W585P,hsp90_585,hsp90,hsp90,P02829,0.793885,NO,585,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-4.251,-3.033,0,5.31455,0.508,,B,1.22,0.43,,,,OHP,-3.17533,0.368192,0.000222939,0.793885 kka2_1:1_G10Q,kka2_1:1_10,Kka2,kka2_1:1,P00552,0.793896,NO,10,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.921,-2.7,0.779,,,,,,,1.862,,71.59,HOP,-2.10733,0.520039,0.00289233,0.793896 beta-lactamase_0_N130T,beta-lactamase_0_130,TEM-1,beta-lactamase_0,P62593,0.793897,NO,130,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-0.798,-3.196,2.398,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.0500837,0.000683376,0.793897 beta-lactamase_R159C,beta-lactamase_159,TEM-1,beta-lactamase,P62593,0.793898,NO,159,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-0.94,-5.113,4.173,5.64971,0.316,,B,0.68,-0.55,1.172,,64.34,PBH,-1.011,0.221079,0.00108472,0.793898 kka2_1:8_L193P,kka2_1:8_193,Kka2,kka2_1:8,P00552,0.793899,NO,193,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.983,-2.872,1.889,,,G,A,1.59,-1.03,2.234,,65.53,OHO,-0.965333,0.100394,0.00480179,0.793899 kka2_1:8_L193P,kka2_1:8_193,Kka2,kka2_1:8,P00552,0.793899,NO,193,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.983,-2.872,1.889,,,G,A,1.59,-1.03,2.234,,65.53,OHO,-0.965333,0.100394,0.00480179,0.793899 kka2_1:2_R202N,kka2_1:2_202,Kka2,kka2_1:2,P00552,0.793985,NO,202,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.761,-3.087,1.326,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.295029,0.00696498,0.793985 beta-lactamase_0_T131K,beta-lactamase_0_131,TEM-1,beta-lactamase_0,P62593,0.79401,NO,131,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.328,-3.481,2.153,,,H,A,0.22,-0.69,3.306,,67.48,PPH,-1.00867,0.0500837,0.00345886,0.79401 kka2_1:1_D82G,kka2_1:1_82,Kka2,kka2_1:1,P00552,0.794013,NO,82,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.946,-2.495,0.549,,0.341,E,b,0.75,0.52,11.345,11.345,63.64,HAH,-1.98,0.520039,0.00637516,0.794013 kka2_1:4_D90G,kka2_1:4_90,Kka2,kka2_1:4,P00552,0.794051,NO,90,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.459,-3.503,1.044,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.168804,0.00583842,0.794051 beta-lactamase_0_G52M,beta-lactamase_0_52,TEM-1,beta-lactamase_0,P62593,0.794114,NO,52,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.149,-4.888,3.739,,0.299,,l,0.29,-0.04,1.164,,64.69,POB,-1.66267,0.0500837,0.00340138,0.794114 kka2_1:2_T187A,kka2_1:2_187,Kka2,kka2_1:2,P00552,0.794217,NO,187,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.273,-1.915,0.642,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.295029,0.00693073,0.794217 beta-lactamase_0_T27G,beta-lactamase_0_27,TEM-1,beta-lactamase_0,P62593,0.794227,NO,27,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.905,-3.36,1.455,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.0500837,0.00306559,0.794227 beta-lactamase_0_S68T,beta-lactamase_0_68,TEM-1,beta-lactamase_0,P62593,0.794354,NO,68,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-0.913,-3.02,2.107,,0.064,G,A,0.27,-1.03,1.441,,64.69,HPP,-1.37233,0.0500837,0.000800065,0.794354 beta-lactamase_G52H,beta-lactamase_52,TEM-1,beta-lactamase,P62593,0.794406,NO,52,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.149,-4.712,3.563,5.12093,0.299,,l,0.77,-0.04,2.103,,64.69,POB,-1.66267,0.221079,0.00340138,0.794406 kka2_1:2_L184M,kka2_1:2_184,Kka2,kka2_1:2,P00552,0.794412,NO,184,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.496,-3.37,1.874,,0.489,E,B,0.55,-0.06,14.044,14.044,63.26,AHH,-1.24833,0.295029,0.00518742,0.794412 kka2_1:8_P109M,kka2_1:8_109,Kka2,kka2_1:8,P00552,0.794496,NO,109,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.412,-4.773,3.361,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.100394,0.0070929,0.794496 kka2_1:8_P109M,kka2_1:8_109,Kka2,kka2_1:8,P00552,0.794496,NO,109,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.412,-4.773,3.361,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.100394,0.0070929,0.794496 beta-lactamase_0_A230D,beta-lactamase_0_230,TEM-1,beta-lactamase_0,P62593,0.794502,NO,230,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.154,-3.645,2.491,,0.01,E,B,0.46,-1.17,2.179,,50,HHA,-1.079,0.0500837,0.00516841,0.794502 beta-lactamase_P105E,beta-lactamase_105,TEM-1,beta-lactamase,P62593,0.794505,NO,105,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.813,-3.437,2.624,5.08236,0.226,T,A,0.98,0.8,1.154,,63.29,POH,-1.01533,0.221079,0.0011981,0.794505 gb1_L238M,gb1_238,gb1,gb1,P06654,0.79459,NO,238,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-2.98,-4.154,1.174,,,,,,,0.504,,45.54,PHB,-2.58633,0.177985,0.00205885,0.79459 gb1_T237G,gb1_237,gb1,gb1,P06654,0.79459,NO,237,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.736,-1.792,0.056,,,,,,,0.218,,11.83,BPH,-2.27833,0.177985,0.00275316,0.79459 beta-lactamase_625_L89D,beta-lactamase_625_89,TEM-1,beta-lactamase_625,P62593,0.794592,NO,89,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.096,-3.996,2.9,,0.168,T,A,0.55,0.63,1.599,,64.34,PHO,-1.75767,0.213352,0.00207068,0.794592 beta-lactamase_0_E169S,beta-lactamase_0_169,TEM-1,beta-lactamase_0,P62593,0.794651,NO,169,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.23,-2.21,0.98,,0.337,,A,1.04,1,3.516,,73.08,PAH,-1.16533,0.0500837,0.00400994,0.794651 beta-lactamase_625_T27N,beta-lactamase_625_27,TEM-1,beta-lactamase_625,P62593,0.79469,NO,27,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.905,-2.525,0.62,,0.007,H,A,0.22,-0.37,3.72,,93.01,APH,-1.97933,0.213352,0.00306559,0.79469 WW_domain_D201P,WW_domain_201,Yap65,WW_domain,P46937,0.794726,NO,201,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.369,-3.543,2.174,4.90312,,,,,,20.806,20.806,70.04,PAO,-1.456,0.153962,0.00248402,0.794726 beta-lactamase_0_T69I,beta-lactamase_0_69,TEM-1,beta-lactamase_0,P62593,0.794733,NO,69,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-0.973,-3.64,2.667,,,G,A,0.22,-1.24,0.505,,93.01,PPH,-1.01833,0.0500837,0.00127498,0.794733 beta-lactamase_2500_R176H,beta-lactamase_2500_176,TEM-1,beta-lactamase_2500,P62593,0.794854,NO,176,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-0.863,-4.23,3.367,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.361275,0.00105554,0.794854 beta-lactamase_2500_R63Q,beta-lactamase_2500_63,TEM-1,beta-lactamase_2500,P62593,0.794856,NO,63,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-0.943,-3.532,2.589,,0.218,,B,1.2,-0.31,0.929,,44.06,ABH,-0.992333,0.361275,0.00126938,0.794856 kka2_1:2_R226S,kka2_1:2_226,Kka2,kka2_1:2,P00552,0.794863,NO,226,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.392,-2.638,1.246,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.295029,0.0108032,0.794863 kka2_1:2_I196F,kka2_1:2_196,Kka2,kka2_1:2,P00552,0.794892,NO,196,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-2.115,-1.503,-0.612,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.295029,0.0107273,0.794892 beta-lactamase_0_L146G,beta-lactamase_0_146,TEM-1,beta-lactamase_0,P62593,0.794933,NO,146,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.462,-3.742,2.28,,0.007,H,A,0.55,-0.56,2.051,,64.69,AHP,-1.656,0.0500837,0.00474542,0.794933 beta-lactamase_39_Y262N,beta-lactamase_39_262,TEM-1,beta-lactamase_39,P62593,0.794955,NO,262,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.0495842,0.00853516,0.794955 beta-lactamase_2500_M127A,beta-lactamase_2500_127,TEM-1,beta-lactamase_2500,P62593,0.794995,NO,127,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-2.251,-3.303,1.052,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.361275,0.00437927,0.794995 beta-lactamase_0_M209R,beta-lactamase_0_209,TEM-1,beta-lactamase_0,P62593,0.795073,NO,209,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.442,-3.939,2.497,,,H,A,0.55,-0.97,3.876,,64.69,HHA,-1.52633,0.0500837,0.00625021,0.795073 beta-lactamase_M66G,beta-lactamase_66,TEM-1,beta-lactamase,P62593,0.795089,NO,66,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.362,-3.751,2.389,5.29561,0.013,,A,1.3,-0.7,1.319,,73.08,OHH,-1.49567,0.221079,0.00412876,0.795089 gb1_A246D,gb1_246,gb1,gb1,P06654,0.795166,NO,246,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.175,-3.429,2.254,,,,,,,,,,AHH,-1.87033,0.177985,0.00190625,0.795166 gb1_N263Q,gb1_263,gb1,gb1,P06654,0.795166,NO,263,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-1.162,-3.451,2.289,,,,,,,,,,APO,-2.04233,0.177985,0.0035297,0.795166 beta-lactamase_156_T263D,beta-lactamase_156_263,TEM-1,beta-lactamase_156,P62593,0.795212,NO,263,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.111618,0.0110582,0.795212 kka2_1:8_A64D,kka2_1:8_64,Kka2,kka2_1:8,P00552,0.795218,NO,64,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.496,-3.892,2.396,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.100394,0.00705578,0.795218 kka2_1:8_A64D,kka2_1:8_64,Kka2,kka2_1:8,P00552,0.795218,NO,64,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.496,-3.892,2.396,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.100394,0.00705578,0.795218 kka2_1:8_A34C,kka2_1:8_34,Kka2,kka2_1:8,P00552,0.79522,NO,34,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.928,-4.523,3.595,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.100394,0.00343484,0.79522 kka2_1:8_A34C,kka2_1:8_34,Kka2,kka2_1:8,P00552,0.79522,NO,34,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.928,-4.523,3.595,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.100394,0.00343484,0.79522 beta-lactamase_156_G52C,beta-lactamase_156_52,TEM-1,beta-lactamase_156,P62593,0.795248,NO,52,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.149,-5.084,3.935,,0.299,,l,0.29,-0.04,1.179,,64.69,POB,-1.66267,0.111618,0.00340138,0.795248 PSD95pdz3_I341Q,PSD95pdz3_341,PSD95pdz3,PSD95pdz3,P31016,0.795278,NO,341,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.63,-4.031,2.401,5.73946,,,,,10.3187,,,,HHH,-1.50033,0.0758425,0.000824087,0.795278 beta-lactamase_G263K,beta-lactamase_263,TEM-1,beta-lactamase,P62593,0.795284,NO,263,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-2.031,-2.807,0.776,5.09799,0.517,S,l,0.77,0.31,16.425,16.425,77.62,POP,-1.78267,0.221079,0.0110582,0.795284 PSD95pdz3_A390D,PSD95pdz3_390,PSD95pdz3,PSD95pdz3,P31016,0.795365,NO,390,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.307,-3.375,2.068,5.03823,,,,,12.46,,,,HHP,-1.54467,0.0758425,0.00104603,0.795365 beta-lactamase_0_I54Q,beta-lactamase_0_54,TEM-1,beta-lactamase_0,P62593,0.79539,NO,54,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-2.838,-2.926,0.088,,0.669,E,B,0.48,-0.14,0.541,,73.78,BHH,-2.337,0.0500837,0.00403589,0.79539 beta-lactamase_2500_T187G,beta-lactamase_2500_187,TEM-1,beta-lactamase_2500,P62593,0.795394,NO,187,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.401,-3.394,1.993,,0.007,H,A,0.22,-1.19,3.91,,67.48,PPH,-1.69633,0.361275,0.00491782,0.795394 beta-lactamase_F228N,beta-lactamase_228,TEM-1,beta-lactamase,P62593,0.7954,NO,228,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-2.342,-3.038,0.696,5.33448,0.154,E,B,1.1,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.221079,0.0046669,0.7954 kka2_1:2_E111K,kka2_1:2_111,Kka2,kka2_1:2,P00552,0.795404,NO,111,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.28,-2.698,0.418,,0.155,H,A,1.52,-1.14,2.792,,65.53,HAB,-2.27833,0.295029,0.00746789,0.795404 kka2_1:2_N200H,kka2_1:2_200,Kka2,kka2_1:2,P00552,0.795469,NO,200,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-2.446,-3.247,0.801,,0.756,T,L,0.61,-0.08,2.836,,64.39,APO,-2.08,0.295029,0.00838549,0.795469 kka2_1:2_G245V,kka2_1:2_245,Kka2,kka2_1:2,P00552,0.795507,NO,245,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.812,-3.749,2.937,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.295029,0.00683899,0.795507 beta-lactamase_0_Y262P,beta-lactamase_0_262,TEM-1,beta-lactamase_0,P62593,0.795547,NO,262,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.0500837,0.00853516,0.795547 kka2_1:8_H162Y,kka2_1:8_162,Kka2,kka2_1:8,P00552,0.795557,NO,162,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-2.319,-3.937,1.618,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.100394,0.00616145,0.795557 kka2_1:8_H162Y,kka2_1:8_162,Kka2,kka2_1:8,P00552,0.795557,NO,162,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-2.319,-3.937,1.618,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.100394,0.00616145,0.795557 kka2_1:8_W236A,kka2_1:8_236,Kka2,kka2_1:8,P00552,0.795602,NO,236,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-1.363,-2.534,1.171,,0.303,H,A,1.51,-0.76,1.87,,48.48,AHH,-1.81267,0.100394,0.0088796,0.795602 kka2_1:8_W236A,kka2_1:8_236,Kka2,kka2_1:8,P00552,0.795602,NO,236,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-1.363,-2.534,1.171,,0.303,H,A,1.51,-0.76,1.87,,48.48,AHH,-1.81267,0.100394,0.0088796,0.795602 beta-lactamase_39_D155M,beta-lactamase_39_155,TEM-1,beta-lactamase_39,P62593,0.795616,NO,155,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.889,-4.929,4.04,,0.049,,B,0.75,-0.9,3.208,,64.69,OAB,-1.62267,0.0495842,0.00135315,0.795616 beta-lactamase_39_D155V,beta-lactamase_39_155,TEM-1,beta-lactamase_39,P62593,0.795626,NO,155,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.889,-3.778,2.889,,0.049,,B,0.75,-0.9,3.208,,64.69,OAB,-1.62267,0.0495842,0.00135315,0.795626 beta-lactamase_0_Y103S,beta-lactamase_0_103,TEM-1,beta-lactamase_0,P62593,0.795653,NO,103,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-1.33,-3.594,2.264,,0.613,S,l,0.21,1.21,1.646,,63.29,AHP,-1.48767,0.0500837,0.00443048,0.795653 kka2_1:2_C31F,kka2_1:2_31,Kka2,kka2_1:2,P00552,0.795786,NO,31,C,F,CF,Special,Hydrophobic,5.07,3.32051,-1.74949,205,121,165,44,108.5,189.9,81.4,-2.246,-4.376,2.13,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.295029,0.00681582,0.795786 beta-lactamase_2500_G194F,beta-lactamase_2500_194,TEM-1,beta-lactamase_2500,P62593,0.795835,NO,194,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.396,-4.382,2.986,,0.276,S,b,0.29,0.36,3.593,,67.83,POA,-1.832,0.361275,0.00392163,0.795835 kka2_1:4_A237I,kka2_1:4_237,Kka2,kka2_1:4,P00552,0.795925,NO,237,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.12,-2.296,0.176,,0.068,H,A,0.46,-0.71,2.444,,92.05,HHA,-2.10433,0.168804,0.012257,0.795925 beta-lactamase_0_D36P,beta-lactamase_0_36,TEM-1,beta-lactamase_0,P62593,0.795983,NO,36,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.732,-3.967,1.235,,0.555,H,A,0.75,1.17,13.689,13.689,77.62,AAP,-1.91167,0.0500837,0.00476483,0.795983 beta-lactamase_D48M,beta-lactamase_48,TEM-1,beta-lactamase,P62593,0.796043,NO,48,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.101,-4.896,3.795,4.89966,0.189,E,B,0.23,0.21,1.281,,50.35,HAH,-1.62467,0.221079,0.0027273,0.796043 beta-lactamase_R159W,beta-lactamase_159,TEM-1,beta-lactamase,P62593,0.796087,NO,159,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-0.94,-5.32,4.38,5.64971,0.316,,B,0.68,-0.55,1.172,,64.34,PBH,-1.011,0.221079,0.00108472,0.796087 kka2_1:4_E182G,kka2_1:4_182,Kka2,kka2_1:4,P00552,0.796127,NO,182,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.516,-2.588,1.072,,0.326,.,B,1.04,0.75,4.755,,65.53,OAA,-1.806,0.168804,0.00641548,0.796127 beta-lactamase_0_K144R,beta-lactamase_0_144,TEM-1,beta-lactamase_0,P62593,0.79615,NO,144,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-2.388,-3.055,0.667,,0.863,H,A,2.34,1.27,5.696,,77.62,OBA,-1.904,0.0500837,0.00481141,0.79615 kka2_1:1_V153L,kka2_1:1_153,Kka2,kka2_1:1,P00552,0.796232,NO,153,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.092,-2.743,1.651,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.520039,0.00501119,0.796232 beta-lactamase_39_D129C,beta-lactamase_39_129,TEM-1,beta-lactamase_39,P62593,0.796279,NO,129,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.816,-5.136,4.32,,,,B,0.75,-0.69,0.56,,34.97,PAP,-0.818,0.0495842,0.00109178,0.796279 beta-lactamase_T126H,beta-lactamase_126,TEM-1,beta-lactamase,P62593,0.796291,NO,126,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.122,-4.699,3.577,4.82694,0.05,H,A,0.3,-0.05,1.14,,44.41,HPH,-1.60467,0.221079,0.00244552,0.796291 kka2_1:8_Y244Q,kka2_1:8_244,Kka2,kka2_1:8,P00552,0.796291,NO,244,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-0.775,-3.928,3.153,,0.066,H,A,1.25,-0.64,,,,HHO,-1.41267,0.100394,0.00453187,0.796291 kka2_1:8_Y244Q,kka2_1:8_244,Kka2,kka2_1:8,P00552,0.796291,NO,244,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-0.775,-3.928,3.153,,0.066,H,A,1.25,-0.64,,,,HHO,-1.41267,0.100394,0.00453187,0.796291 gb1_K254I,gb1_254,gb1,gb1,P06654,0.796311,NO,254,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.748,-3.876,2.128,,,,,,,1.793,,37.28,ABH,-2.195,0.177985,0.00622711,0.796311 kka2_1:1_V46N,kka2_1:1_46,Kka2,kka2_1:1,P00552,0.796315,NO,46,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-2.62,-3.225,0.605,,0.192,.,B,0.44,-1.12,20.149,20.149,92.05,OHH,-1.88633,0.520039,0.00631301,0.796315 beta-lactamase_625_L73Q,beta-lactamase_625_73,TEM-1,beta-lactamase_625,P62593,0.796332,NO,73,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.507,-4.261,2.754,,,H,A,0.55,-0.64,2.933,,67.83,HHH,-1.487,0.213352,0.00488983,0.796332 beta-lactamase_2500_R176M,beta-lactamase_2500_176,TEM-1,beta-lactamase_2500,P62593,0.796338,NO,176,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-0.863,-4.48,3.617,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.361275,0.00105554,0.796338 beta-lactamase_156_S104F,beta-lactamase_156_104,TEM-1,beta-lactamase_156,P62593,0.796363,NO,104,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.015,-4.127,3.112,,0.04,,b,0.27,0.57,4.02,,63.29,HPO,-1.05267,0.111618,0.00218083,0.796363 beta-lactamase_39_L205H,beta-lactamase_39_205,TEM-1,beta-lactamase_39,P62593,0.796374,NO,205,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.922,-4.828,3.906,,,H,A,0.55,-0.46,0.846,,42.31,PHH,-1.57767,0.0495842,0.00255802,0.796374 kka2_1:2_A247Y,kka2_1:2_247,Kka2,kka2_1:2,P00552,0.796462,NO,247,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.459,-4.278,1.819,,1.01,S,A,0.46,0.65,0.828,,92.05,HHH,-2.197,0.295029,0.0102428,0.796462 beta-lactamase_0_G141T,beta-lactamase_0_141,TEM-1,beta-lactamase_0,P62593,0.796463,NO,141,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.828,-3.647,2.819,,0.575,T,l,0.29,-0.28,0.722,,64.69,HOO,-1.08933,0.0500837,0.0012419,0.796463 kka2_1:1_I228T,kka2_1:1_228,Kka2,kka2_1:1,P00552,0.796484,NO,228,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.142,-3.482,2.34,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.520039,0.00458834,0.796484 PSD95pdz3_G345N,PSD95pdz3_345,PSD95pdz3,PSD95pdz3,P31016,0.79653,NO,345,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.008,-3.13,2.122,4.32868,,,,,13.165,,,,OOO,-1.084,0.0758425,0.000771806,0.79653 kka2_1:1_V49L,kka2_1:1_49,Kka2,kka2_1:1,P00552,0.79663,NO,49,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.614,-1.314,-0.3,,,E,B,0.44,-0.77,3.665,3.665,64.39,HHB,-1.3,0.520039,0.00615685,0.79663 beta-lactamase_0_S68C,beta-lactamase_0_68,TEM-1,beta-lactamase_0,P62593,0.796673,NO,68,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-0.913,-4.705,3.792,,0.064,G,A,0.27,-1.03,1.441,,64.69,HPP,-1.37233,0.0500837,0.000800065,0.796673 beta-lactamase_0_L137R,beta-lactamase_0_137,TEM-1,beta-lactamase_0,P62593,0.796738,NO,137,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.03,-4,2.97,,,H,A,0.55,-0.38,0.328,,42.31,HHP,-1.58933,0.0500837,0.00278599,0.796738 beta-lactamase_0_L248Q,beta-lactamase_0_248,TEM-1,beta-lactamase_0,P62593,0.796743,NO,248,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.0500837,0.00428493,0.796743 kka2_1:1_A79E,kka2_1:1_79,Kka2,kka2_1:1,P00552,0.796784,NO,79,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.368,-2.303,-0.065,,0.563,.,B,0.46,-0.43,7.792,7.792,71.59,HHH,-1.752,0.520039,0.00664821,0.796784 beta-lactamase_0_I229V,beta-lactamase_0_229,TEM-1,beta-lactamase_0,P62593,0.796845,NO,229,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.267,-1.684,0.417,,0.083,E,B,0.48,-0.76,1.69,,50,HHH,-1.58767,0.0500837,0.00477249,0.796845 kka2_1:1_L19V,kka2_1:1_19,Kka2,kka2_1:1,P00552,0.796874,NO,19,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.254,-2.596,1.342,,0.08,T,A,0.55,-0.26,17.165,17.165,65.53,BHH,-2.221,0.520039,0.00620703,0.796874 kka2_1:4_S114D,kka2_1:4_114,Kka2,kka2_1:4,P00552,0.796935,NO,114,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.527,-2.691,0.164,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.168804,0.00705262,0.796935 beta-lactamase_L89G,beta-lactamase_89,TEM-1,beta-lactamase,P62593,0.796939,NO,89,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.096,-3.653,2.557,5.41092,0.168,T,A,1.75,0.63,1.599,,64.34,PHO,-1.75767,0.221079,0.00207068,0.796939 beta-lactamase_E119T,beta-lactamase_119,TEM-1,beta-lactamase,P62593,0.796978,NO,119,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.412,-3.526,2.114,5.33349,0.358,H,A,1.52,0.51,1.983,,63.99,BAH,-1.623,0.221079,0.00386966,0.796978 kka2_1:4_Y22C,kka2_1:4_22,Kka2,kka2_1:4,P00552,0.79702,NO,22,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-1.583,-3.399,1.816,,0.122,.,B,0.21,-0.8,1.838,,65.53,OHA,-1.80333,0.168804,0.00598977,0.79702 kka2_1:8_C209R,kka2_1:8_209,Kka2,kka2_1:8,P00552,0.797054,NO,209,C,R,CR,Special,PositiveCharge,5.07,6.34148,1.27148,180,121,174,53,108.5,173.4,64.9,-0.906,-4.184,3.278,,,,a,1.5,-0.89,0.391,,19.32,AOO,-0.903,0.100394,0.00260862,0.797054 kka2_1:8_C209R,kka2_1:8_209,Kka2,kka2_1:8,P00552,0.797054,NO,209,C,R,CR,Special,PositiveCharge,5.07,6.34148,1.27148,180,121,174,53,108.5,173.4,64.9,-0.906,-4.184,3.278,,,,a,1.5,-0.89,0.391,,19.32,AOO,-0.903,0.100394,0.00260862,0.797054 kka2_1:8_R140K,kka2_1:8_140,Kka2,kka2_1:8,P00552,0.797054,NO,140,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.351,-2.269,0.918,,0.12,H,A,0.16,0.2,2.874,,53.03,BBH,-1.885,0.100394,0.00430167,0.797054 kka2_1:8_R140K,kka2_1:8_140,Kka2,kka2_1:8,P00552,0.797054,NO,140,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.351,-2.269,0.918,,0.12,H,A,0.16,0.2,2.874,,53.03,BBH,-1.885,0.100394,0.00430167,0.797054 beta-lactamase_39_G142W,beta-lactamase_39_142,TEM-1,beta-lactamase_39,P62593,0.797059,NO,142,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.707,-5.146,4.439,,0.034,,p,0.29,-0.64,1.947,,64.69,OOO,-0.834,0.0495842,0.00060149,0.797059 beta-lactamase_0_W288Y,beta-lactamase_0_288,TEM-1,beta-lactamase_0,P62593,0.797099,NO,288,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,,,,,,,,,,,,,BHO,,0.0500837,,0.797099 beta-lactamase_2500_G90P,beta-lactamase_2500_90,TEM-1,beta-lactamase_2500,P62593,0.797147,NO,90,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-2.091,-3.952,1.861,,0.598,T,A,0.29,0.32,1.2,,77.62,HOB,-1.52633,0.361275,0.00490273,0.797147 beta-lactamase_0_T126P,beta-lactamase_0_126,TEM-1,beta-lactamase_0,P62593,0.797192,NO,126,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.122,-3.758,2.636,,0.05,H,A,0.22,-0.05,0.705,,44.41,HPH,-1.60467,0.0500837,0.00244552,0.797192 kka2_1:8_A237G,kka2_1:8_237,Kka2,kka2_1:8,P00552,0.797298,NO,237,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.12,-3.628,1.508,,0.068,H,A,0.46,-0.71,0.449,,92.05,HHA,-2.10433,0.100394,0.012257,0.797298 kka2_1:8_A237G,kka2_1:8_237,Kka2,kka2_1:8,P00552,0.797298,NO,237,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.12,-3.628,1.508,,0.068,H,A,0.46,-0.71,0.449,,92.05,HHA,-2.10433,0.100394,0.012257,0.797298 kka2_1:4_I207L,kka2_1:4_207,Kka2,kka2_1:4,P00552,0.797359,NO,207,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.175,-2.098,0.923,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.168804,0.00611824,0.797359 kka2_1:4_F206M,kka2_1:4_206,Kka2,kka2_1:4,P00552,0.797373,NO,206,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.349,-3.155,1.806,,0.006,E,B,0.58,-1.21,1.342,,63.64,OHH,-1.04,0.168804,0.00936868,0.797373 kka2_1:2_I254A,kka2_1:2_254,Kka2,kka2_1:2,P00552,0.797409,NO,254,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.933,-2.534,0.601,,0.135,H,A,1.52,-0.6,2.562,,71.59,BHH,-1.668,0.295029,0.0132375,0.797409 kka2_1:8_R38S,kka2_1:8_38,Kka2,kka2_1:8,P00552,0.79742,NO,38,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.207,-3.563,2.356,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.100394,0.00372499,0.79742 kka2_1:8_R38S,kka2_1:8_38,Kka2,kka2_1:8,P00552,0.79742,NO,38,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.207,-3.563,2.356,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.100394,0.00372499,0.79742 kka2_1:2_L243N,kka2_1:2_243,Kka2,kka2_1:2,P00552,0.797453,NO,243,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-2.651,-3.218,0.567,,0.277,H,A,1.59,-0.67,13.165,13.165,92.05,HHH,-2.03767,0.295029,0.00884927,0.797453 kka2_1:8_L193Q,kka2_1:8_193,Kka2,kka2_1:8,P00552,0.797481,NO,193,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.983,-2.972,1.989,,,G,A,1.59,-1.03,2.234,,65.53,OHO,-0.965333,0.100394,0.00480179,0.797481 kka2_1:8_L193Q,kka2_1:8_193,Kka2,kka2_1:8,P00552,0.797481,NO,193,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.983,-2.972,1.989,,,G,A,1.59,-1.03,2.234,,65.53,OHO,-0.965333,0.100394,0.00480179,0.797481 beta-lactamase_156_A132C,beta-lactamase_156_132,TEM-1,beta-lactamase_156,P62593,0.797502,NO,132,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.9,-4.503,3.603,,,H,A,0.46,-0.93,10.621,,64.69,PHH,-1.138,0.111618,0.000962524,0.797502 beta-lactamase_2500_M270A,beta-lactamase_2500_270,TEM-1,beta-lactamase_2500,P62593,0.797517,NO,270,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.723,,,,0.422,H,A,1.59,1.15,2.029,,64.34,PHA,-1.70933,0.361275,0.00767762,0.797517 beta-lactamase_2500_M115I,beta-lactamase_2500_115,TEM-1,beta-lactamase_2500,P62593,0.79752,NO,115,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.389,-3.258,1.869,,0.019,E,B,0.55,0.08,3.261,,69.58,OHP,-1.25433,0.361275,0.0034337,0.79752 kka2_1:2_M197C,kka2_1:2_197,Kka2,kka2_1:2,P00552,0.797528,NO,197,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.707,-4.828,3.121,,0.121,E,B,0.55,-1.19,2.097,,65.53,HHH,-1.847,0.295029,0.00921295,0.797528 kka2_1:2_G74T,kka2_1:2_74,Kka2,kka2_1:2,P00552,0.797593,NO,74,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.18,-3.624,2.444,,0.621,T,l,0.75,0.2,1.446,,64.39,POH,-1.91667,0.295029,0.00587035,0.797593 kka2_1:2_S104G,kka2_1:2_104,Kka2,kka2_1:2,P00552,0.797593,NO,104,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.436,-3.347,1.911,,0.536,T,A,0.27,-1.11,5.49,,63.64,HPP,-1.91433,0.295029,0.00555207,0.797593 kka2_1:4_R239G,kka2_1:4_239,Kka2,kka2_1:4,P00552,0.797595,NO,239,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.949,-2.877,-0.072,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.168804,0.00835326,0.797595 kka2_1:1_M148I,kka2_1:1_148,Kka2,kka2_1:1,P00552,0.797728,NO,148,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.847,-2.616,0.769,,0.268,H,A,1.59,0.71,4.618,,64.39,BHA,-1.65467,0.520039,0.00982664,0.797728 kka2_1:1_M197I,kka2_1:1_197,Kka2,kka2_1:1,P00552,0.797749,NO,197,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.707,-1.88,0.173,,0.121,E,B,1.59,-1.19,2.097,,65.53,HHH,-1.847,0.520039,0.00921295,0.797749 kka2_1:8_L47P,kka2_1:8_47,Kka2,kka2_1:8,P00552,0.797785,NO,47,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.265,-4.146,2.881,,0.139,E,B,1.59,-0.86,5.086,,63.26,HHH,-1.77933,0.100394,0.00509386,0.797785 kka2_1:8_L47P,kka2_1:8_47,Kka2,kka2_1:8,P00552,0.797785,NO,47,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.265,-4.146,2.881,,0.139,E,B,1.59,-0.86,5.086,,63.26,HHH,-1.77933,0.100394,0.00509386,0.797785 kka2_1:4_A144V,kka2_1:4_144,Kka2,kka2_1:4,P00552,0.797795,NO,144,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.859,-2.095,1.236,,,H,A,0.46,0.21,6.844,,52.65,BHB,-1.72933,0.168804,0.00231095,0.797795 beta-lactamase_0_A225M,beta-lactamase_0_225,TEM-1,beta-lactamase_0,P62593,0.797812,NO,225,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.845,-4.778,2.933,,1,T,B,0.46,-0.38,11.722,11.722,74.48,OHO,-1.39967,0.0500837,0.00465057,0.797812 beta-lactamase_0_L136F,beta-lactamase_0_136,TEM-1,beta-lactamase_0,P62593,0.797848,NO,136,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.232,-3.77,2.538,,,H,A,0.55,-0.34,0.648,,48.95,HHH,-1.088,0.0500837,0.00442304,0.797848 beta-lactamase_625_A40D,beta-lactamase_625_40,TEM-1,beta-lactamase_625,P62593,0.797857,NO,40,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.402,-3.685,2.283,,0.155,S,B,0.46,0.21,1.357,,73.78,OHB,-1.40267,0.213352,0.00490026,0.797857 beta-lactamase_0_P250Q,beta-lactamase_0_250,TEM-1,beta-lactamase_0,P62593,0.797934,NO,250,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.0500837,0.00550899,0.797934 beta-lactamase_39_V31H,beta-lactamase_39_31,TEM-1,beta-lactamase_39,P62593,0.797948,NO,31,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.822,-4.968,3.146,,,H,A,0.44,-0.46,2.885,,73.78,BHB,-2.03767,0.0495842,0.00478065,0.797948 beta-lactamase_0_S80K,beta-lactamase_0_80,TEM-1,beta-lactamase_0,P62593,0.797957,NO,80,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.029,-2.901,0.872,,0.192,H,A,0.27,0.46,12.403,12.403,77.62,HPB,-1.44567,0.0500837,0.00565569,0.797957 beta-lactamase_0_T158Y,beta-lactamase_0_158,TEM-1,beta-lactamase_0,P62593,0.798032,NO,158,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.116,-4.258,3.142,,0.036,,B,0.22,-0.85,1.041,,69.58,HPB,-1.269,0.0500837,0.00341825,0.798032 beta-lactamase_0_D177H,beta-lactamase_0_177,TEM-1,beta-lactamase_0,P62593,0.798061,NO,177,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.967,-4.511,3.544,,0.006,T,L,0.75,-1.02,3.536,,64.69,BAP,-0.873667,0.0500837,0.000864022,0.798061 kka2_1:1_T146A,kka2_1:1_146,Kka2,kka2_1:1,P00552,0.798195,NO,146,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.978,-1.627,-1.351,,0.281,H,A,0.82,0.78,2.105,,92.05,BPB,-1.96833,0.520039,0.00606474,0.798195 hsp90_F583A,hsp90_583,hsp90,hsp90,P02829,0.798211,NO,583,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-3.22,-2.456,0,5.28185,1.112,S,l,1.1,0.87,,,,PHO,-3.003,0.368192,0.000222939,0.798211 beta-lactamase_0_L111P,beta-lactamase_0_111,TEM-1,beta-lactamase_0,P62593,0.798228,NO,111,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.76,-4.076,2.316,,0.328,T,A,0.55,0.93,1.966,,64.34,BHP,-1.884,0.0500837,0.00480671,0.798228 beta-lactamase_2500_V259L,beta-lactamase_2500_259,TEM-1,beta-lactamase_2500,P62593,0.79823,NO,259,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.361275,0.0070773,0.79823 Pab1_I137T,Pab1_137,Pab1,Pab1,P04147,0.798245,NO,137,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.212,-3.239,2.027,,0.068,,B,0.77,0.35,,,,AHA,-1.314,0.175299,0.000342224,0.798245 beta-lactamase_V101W,beta-lactamase_101,TEM-1,beta-lactamase,P62593,0.798264,NO,101,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.295,-5.385,4.09,5.49045,0.342,,B,0.96,0,1.675,,73.08,HHA,-1.54367,0.221079,0.00374492,0.798264 beta-lactamase_0_G114N,beta-lactamase_0_114,TEM-1,beta-lactamase_0,P62593,0.798271,NO,114,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.094,-2.731,1.637,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.0500837,0.00224919,0.798271 kka2_1:4_D90A,kka2_1:4_90,Kka2,kka2_1:4,P00552,0.798275,NO,90,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.459,-3.423,0.964,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.168804,0.00583842,0.798275 beta-lactamase_0_T179F,beta-lactamase_0_179,TEM-1,beta-lactamase_0,P62593,0.798285,NO,179,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.085,-4.108,3.023,,,E,B,0.22,-1.38,0.367,,73.08,PPH,-1.557,0.0500837,0.00226045,0.798285 beta-lactamase_0_Q276D,beta-lactamase_0_276,TEM-1,beta-lactamase_0,P62593,0.798373,NO,276,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.0500837,0.0191712,0.798373 Ubiquitin_A46V,Ubiquitin_46,Uba1,Ubiquitin,P0CG48,0.798387,NO,46,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.77,-2.836,1.066,5.38761,0.398,T,L,2.34,-0.8,6.506,,51.09,HHO,-1.505,0.205827,0.000581142,0.798387 Ubiquitin_D24W,Ubiquitin_24,Uba1,Ubiquitin,P0CG48,0.798387,NO,24,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,,,,,,,,,,,,,HAP,,0.205827,0.0066591,0.798387 Ubiquitin_G35Y,Ubiquitin_35,Uba1,Ubiquitin,P0CG48,0.798387,NO,35,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.171,-2.892,1.721,4.96213,0.713,,L,,0.2,,,,AOH,-1.314,0.205827,0.000648878,0.798387 Ubiquitin_H68C,Ubiquitin_68,Uba1,Ubiquitin,P0CG48,0.798387,NO,68,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-1.869,-5.055,3.186,4.81902,0.194,E,B,0.72,-1.02,21.325,21.325,65.11,HBH,-1.583,0.205827,0.000925438,0.798387 Ubiquitin_H68Q,Ubiquitin_68,Uba1,Ubiquitin,P0CG48,0.798387,NO,68,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-1.869,-4.028,2.159,4.81902,0.194,E,B,0.72,-1.02,21.325,21.325,65.11,HBH,-1.583,0.205827,0.000925438,0.798387 Ubiquitin_H68S,Ubiquitin_68,Uba1,Ubiquitin,P0CG48,0.798387,NO,68,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-1.869,-2.85,0.981,4.81902,0.194,E,B,0.72,-1.02,21.325,21.325,65.11,HBH,-1.583,0.205827,0.000925438,0.798387 Ubiquitin_I44C,Ubiquitin_44,Uba1,Ubiquitin,P0CG48,0.798387,NO,44,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.566,-4.797,3.231,4.71256,,E,B,0.27,-1.17,5.26,,39.71,HHH,-1.38567,0.205827,0.000613305,0.798387 Ubiquitin_I61A,Ubiquitin_61,Uba1,Ubiquitin,P0CG48,0.798387,NO,61,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.514,-3.109,1.595,5.19922,0.038,,B,1,-0.76,1.953,,24.53,PHP,-1.70833,0.205827,0.000738268,0.798387 Ubiquitin_N60Y,Ubiquitin_60,Uba1,Ubiquitin,P0CG48,0.798387,NO,60,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-1.775,-4.365,2.59,5.00332,0.775,T,L,,0.33,,,,HPH,-1.532,0.205827,0.000814061,0.798387 Ubiquitin_Q40Y,Ubiquitin_40,Uba1,Ubiquitin,P0CG48,0.798387,NO,40,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-1.752,-3.025,1.273,4.7807,0.387,G,A,,0.03,,,,APP,-1.62433,0.205827,0.000619089,0.798387 Ubiquitin_S65E,Ubiquitin_65,Uba1,Ubiquitin,P0CG48,0.798387,NO,65,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.535,-2.753,1.218,4.99442,0.168,,b,0.25,-0.68,16.756,16.756,33.87,APP,-1.626,0.205827,0.000546776,0.798387 Ubiquitin_Y59L,Ubiquitin_59,Uba1,Ubiquitin,P0CG48,0.798387,NO,59,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-1.307,-3.261,1.954,5.05599,0.072,G,A,0.43,-0.74,2.566,,24.53,AHP,-1.568,0.205827,0.000775084,0.798387 beta-lactamase_0_K53E,beta-lactamase_0_53,TEM-1,beta-lactamase_0,P62593,0.798399,NO,53,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-2.313,-2.655,0.342,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.0500837,0.00383383,0.798399 beta-lactamase_0_A133R,beta-lactamase_0_133,TEM-1,beta-lactamase_0,P62593,0.798477,NO,133,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.186,-3.865,2.679,,,H,A,0.46,-0.86,2.148,,67.83,HHP,-0.988333,0.0500837,0.00468022,0.798477 kka2_1:8_H135N,kka2_1:8_135,Kka2,kka2_1:8,P00552,0.798514,NO,135,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-1.331,-3.533,2.202,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.100394,0.00532566,0.798514 kka2_1:8_H135N,kka2_1:8_135,Kka2,kka2_1:8,P00552,0.798514,NO,135,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-1.331,-3.533,2.202,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.100394,0.00532566,0.798514 kka2_1:4_V46L,kka2_1:4_46,Kka2,kka2_1:4,P00552,0.798518,NO,46,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-2.62,-3.558,0.938,,0.192,.,B,0.44,-1.12,9.564,,92.05,OHH,-1.88633,0.168804,0.00631301,0.798518 beta-lactamase_0_L89I,beta-lactamase_0_89,TEM-1,beta-lactamase_0,P62593,0.798533,NO,89,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.096,-3.166,2.07,,0.168,T,A,0.55,0.63,2.373,,64.34,PHO,-1.75767,0.0500837,0.00207068,0.798533 beta-lactamase_0_G85L,beta-lactamase_0_85,TEM-1,beta-lactamase_0,P62593,0.798561,NO,85,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.011,-3.755,2.744,,0.805,T,l,0.29,1.7,2.25,,63.64,HOP,-1.68733,0.0500837,0.00252173,0.798561 beta-lactamase_2500_R81Y,beta-lactamase_2500_81,TEM-1,beta-lactamase_2500,P62593,0.798568,NO,81,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.466,-4.271,2.805,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.361275,0.00499763,0.798568 beta-lactamase_39_G249F,beta-lactamase_39_249,TEM-1,beta-lactamase_39,P62593,0.798575,NO,249,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.312,,,,0.256,S,B,0.23,0.04,30.841,30.841,72.73,HOO,-1.81367,0.0495842,0.00220169,0.798575 gb1_V255E,gb1_255,gb1,gb1,P06654,0.798577,NO,255,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-3.127,-2.195,-0.932,,,,,,,1.323,,45.54,BHH,-2.03867,0.177985,0.00408354,0.798577 beta-lactamase_L136A,beta-lactamase_136,TEM-1,beta-lactamase,P62593,0.798593,NO,136,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.232,-3.144,1.912,5.31114,,H,A,2.89,-0.34,1.539,,48.95,HHH,-1.088,0.221079,0.00442304,0.798593 beta-lactamase_0_F70D,beta-lactamase_0_70,TEM-1,beta-lactamase_0,P62593,0.798594,NO,70,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.169,-3.91,2.741,,,H,A,0.58,-1.34,2.153,,63.99,PHB,-0.980667,0.0500837,0.00193499,0.798594 beta-lactamase_0_A282V,beta-lactamase_0_282,TEM-1,beta-lactamase_0,P62593,0.798614,NO,282,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.0500837,0.0449821,0.798614 PSD95pdz3_K380E,PSD95pdz3_380,PSD95pdz3,PSD95pdz3,P31016,0.798661,NO,380,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.416,-2.672,1.256,5.87979,,,,,19.6722,,,,HBP,-1.391,0.0758425,0.000281399,0.798661 beta-lactamase_0_E279N,beta-lactamase_0_279,TEM-1,beta-lactamase_0,P62593,0.798675,NO,279,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.0500837,0.0192826,0.798675 beta-lactamase_0_Y95I,beta-lactamase_0_95,TEM-1,beta-lactamase_0,P62593,0.798723,NO,95,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-1.715,-1.963,0.248,,0.122,,b,0.21,-0.37,2.914,,77.62,BHP,-2.16167,0.0500837,0.00479449,0.798723 kka2_1:1_W24C,kka2_1:1_24,Kka2,kka2_1:1,P00552,0.798983,NO,24,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-1.779,-3.129,1.35,,0.477,E,B,0.47,-0.21,2.375,,56.06,AHH,-2.24467,0.520039,0.00631564,0.798983 beta-lactamase_P25A,beta-lactamase_25,TEM-1,beta-lactamase,P62593,0.799005,NO,25,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.526,-2.222,0.696,5.6134,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.221079,0.00347571,0.799005 beta-lactamase_0_W208C,beta-lactamase_0_208,TEM-1,beta-lactamase_0,P62593,0.799035,NO,208,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-0.818,-4.862,4.044,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.0500837,0.00126609,0.799035 beta-lactamase_I54D,beta-lactamase_54,TEM-1,beta-lactamase,P62593,0.799107,NO,54,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-2.838,-3.732,0.894,5.40541,0.669,E,B,0.77,-0.14,3.946,,73.78,BHH,-2.337,0.221079,0.00403589,0.799107 beta-lactamase_156_D161W,beta-lactamase_156_161,TEM-1,beta-lactamase_156,P62593,0.799161,NO,161,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.891,-5.546,4.655,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.111618,0.000897697,0.799161 beta-lactamase_0_T187Q,beta-lactamase_0_187,TEM-1,beta-lactamase_0,P62593,0.799205,NO,187,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.401,-4.004,2.603,,0.007,H,A,0.22,-1.19,3.259,,67.48,PPH,-1.69633,0.0500837,0.00491782,0.799205 beta-lactamase_0_W227T,beta-lactamase_0_227,TEM-1,beta-lactamase_0,P62593,0.799283,NO,227,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-0.982,-3.696,2.714,,0.272,,B,0.47,-0.29,3.782,,74.48,OHH,-1.595,0.0500837,0.00226019,0.799283 beta-lactamase_39_G236W,beta-lactamase_39_236,TEM-1,beta-lactamase_39,P62593,0.799327,NO,236,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.784,-5.189,4.405,,0.241,,b,0.29,-0.59,1.883,,64.69,HOO,-1.025,0.0495842,0.00162372,0.799327 hsp90_F583M,hsp90_583,hsp90,hsp90,P02829,0.799369,NO,583,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-3.22,-3.858,0,5.28185,1.112,S,l,1.1,0.87,,,,PHO,-3.003,0.368192,0.000222939,0.799369 kka2_1:2_A65Y,kka2_1:2_65,Kka2,kka2_1:2,P00552,0.799389,NO,65,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.744,-4.354,2.61,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.295029,0.00709258,0.799389 kka2_1:2_P98T,kka2_1:2_98,Kka2,kka2_1:2,P00552,0.799395,NO,98,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.526,-2.967,1.441,,0.391,S,B,0.52,-0.65,2.82,,63.26,HOO,-1.19167,0.295029,0.00622754,0.799395 beta-lactamase_2500_E279Y,beta-lactamase_2500_279,TEM-1,beta-lactamase_2500,P62593,0.799454,NO,279,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.361275,0.0192826,0.799454 hsp90_N588C,hsp90_588,hsp90,hsp90,P02829,0.799588,NO,588,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-3.051,-4.015,0,4.61142,0.019,H,A,0.14,0.39,,,,HPH,-3.12167,0.368192,0.000222939,0.799588 beta-lactamase_R176V,beta-lactamase_176,TEM-1,beta-lactamase,P62593,0.799637,NO,176,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-0.863,-3.754,2.891,5.61264,0.385,T,B,0.68,-0.63,,,,ABA,-1.38867,0.221079,0.00105554,0.799637 gb1_Y229I,gb1_229,gb1,gb1,P06654,0.799699,NO,229,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-1.282,-3.296,2.014,,,,,,,,,,PHB,-1.4915,0.177985,0.00366605,0.799699 kka2_1:4_L193C,kka2_1:4_193,Kka2,kka2_1:4,P00552,0.79977,NO,193,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.983,-4.807,3.824,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.168804,0.00480179,0.79977 beta-lactamase_V214G,beta-lactamase_214,TEM-1,beta-lactamase,P62593,0.799771,NO,214,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.299,-3.571,2.272,5.74008,0.375,S,A,1.19,-0.44,1.899,,74.48,BHH,-1.53733,0.221079,0.00628442,0.799771 kka2_1:2_D227C,kka2_1:2_227,Kka2,kka2_1:2,P00552,0.799779,NO,227,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.758,-4.819,3.061,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.295029,0.00745029,0.799779 kka2_1:2_A172F,kka2_1:2_172,Kka2,kka2_1:2,P00552,0.799803,NO,172,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.757,-4.4,2.643,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.295029,0.0079265,0.799803 beta-lactamase_L89S,beta-lactamase_89,TEM-1,beta-lactamase,P62593,0.799825,NO,89,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.096,-3.54,2.444,5.41092,0.168,T,A,1.75,0.63,1.599,,64.34,PHO,-1.75767,0.221079,0.00207068,0.799825 beta-lactamase_2500_P224K,beta-lactamase_2500_224,TEM-1,beta-lactamase_2500,P62593,0.799906,NO,224,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.893,-3.389,2.496,,0.383,,B,0.52,-0.3,2.666,,74.48,HOH,-1.26433,0.361275,0.00189564,0.799906 kka2_1:4_S204N,kka2_1:4_204,Kka2,kka2_1:4,P00552,0.800021,NO,204,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.353,-3.559,2.206,,0.144,E,A,0.27,-1.2,2.442,,65.53,HPO,-0.953333,0.168804,0.00881794,0.800021 beta-lactamase_0_K144P,beta-lactamase_0_144,TEM-1,beta-lactamase_0,P62593,0.800121,NO,144,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-2.388,-2.633,0.245,,0.863,H,A,2.34,1.27,5.696,,77.62,OBA,-1.904,0.0500837,0.00481141,0.800121 beta-lactamase_0_W208V,beta-lactamase_0_208,TEM-1,beta-lactamase_0,P62593,0.800155,NO,208,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-0.818,-3.754,2.936,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.0500837,0.00126609,0.800155 beta-lactamase_0_G154L,beta-lactamase_0_154,TEM-1,beta-lactamase_0,P62593,0.800225,NO,154,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.823,-3.779,2.956,,0.54,T,l,0.29,-0.56,3.629,,64.69,HOA,-1.635,0.0500837,0.00180205,0.800225 beta-lactamase_625_G265P,beta-lactamase_625_265,TEM-1,beta-lactamase_625,P62593,0.800269,NO,265,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.213352,0.00811926,0.800269 beta-lactamase_2500_L38F,beta-lactamase_2500_38,TEM-1,beta-lactamase_2500,P62593,0.800274,NO,38,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.343,-3.81,2.467,,0.088,H,A,0.55,0.2,2.71,,64.34,PHO,-1.78033,0.361275,0.00373244,0.800274 beta-lactamase_156_L47N,beta-lactamase_156_47,TEM-1,beta-lactamase_156,P62593,0.800329,NO,47,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.876,-3.972,2.096,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.111618,0.00439844,0.800329 beta-lactamase_0_R257I,beta-lactamase_0_257,TEM-1,beta-lactamase_0,P62593,0.800336,NO,257,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.0500837,0.00756629,0.800336 beta-lactamase_0_F70E,beta-lactamase_0_70,TEM-1,beta-lactamase_0,P62593,0.800338,NO,70,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.169,-3.82,2.651,,,H,A,0.58,-1.34,2.153,,63.99,PHB,-0.980667,0.0500837,0.00193499,0.800338 beta-lactamase_39_V259G,beta-lactamase_39_259,TEM-1,beta-lactamase_39,P62593,0.800411,NO,259,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.0495842,0.0070773,0.800411 beta-lactamase_156_A185M,beta-lactamase_156_185,TEM-1,beta-lactamase_156,P62593,0.800474,NO,185,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.406,-4.39,2.984,,,H,A,0.46,-1.02,0.365,,65.03,HHP,-1.84033,0.111618,0.00467449,0.800474 beta-lactamase_A40W,beta-lactamase_40,TEM-1,beta-lactamase,P62593,0.800485,NO,40,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.402,-5.298,3.896,4.9697,0.155,S,B,1.2,0.21,1.714,,73.78,OHB,-1.40267,0.221079,0.00490026,0.800485 beta-lactamase_0_K53M,beta-lactamase_0_53,TEM-1,beta-lactamase_0,P62593,0.800488,NO,53,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-2.313,-4.641,2.328,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.0500837,0.00383383,0.800488 kka2_1:2_G164A,kka2_1:2_164,Kka2,kka2_1:2,P00552,0.800624,NO,164,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.869,-3.006,2.137,,0.862,T,l,0.75,1.45,1.539,,64.39,POH,-1.828,0.295029,0.00442091,0.800624 kka2_1:1_R253L,kka2_1:1_253,Kka2,kka2_1:1,P00552,0.800645,NO,253,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.356,-3.455,2.099,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.520039,0.0144195,0.800645 beta-lactamase_2500_R202G,beta-lactamase_2500_202,TEM-1,beta-lactamase_2500,P62593,0.800668,NO,202,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.292,-3.349,2.057,,0.188,H,A,1.2,0.62,3.734,,77.62,PBP,-1.54767,0.361275,0.00321899,0.800668 beta-lactamase_0_S233C,beta-lactamase_0_233,TEM-1,beta-lactamase_0,P62593,0.800715,NO,233,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.886,-4.789,2.903,,0.016,E,B,0.27,-1.01,3.579,,77.62,BPO,-1.17267,0.0500837,0.00311415,0.800715 kka2_1:2_I29D,kka2_1:2_29,Kka2,kka2_1:2,P00552,0.800787,NO,29,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.692,-3.047,1.355,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.295029,0.00619521,0.800787 kka2_1:4_G201S,kka2_1:4_201,Kka2,kka2_1:4,P00552,0.800819,NO,201,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.56,-2.438,0.878,,0.149,T,l,0.29,-0.57,0.284,,52.65,POB,-1.92233,0.168804,0.00820117,0.800819 beta-lactamase_0_E46C,beta-lactamase_0_46,TEM-1,beta-lactamase_0,P62593,0.800851,NO,46,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.94,-3.249,1.309,,0.021,E,B,1.04,0.14,30.306,30.306,59.44,HAH,-2.079,0.0500837,0.00427568,0.800851 kka2_1:2_Q100P,kka2_1:2_100,Kka2,kka2_1:2,P00552,0.800868,NO,100,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.77,-4.125,1.355,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.295029,0.0066405,0.800868 kka2_1:2_R89C,kka2_1:2_89,Kka2,kka2_1:2,P00552,0.800873,NO,89,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.548,-5.235,3.687,,0.209,E,B,1.2,1.41,14.396,14.396,64.39,OBA,-1.89867,0.295029,0.00524373,0.800873 beta-lactamase_0_M115A,beta-lactamase_0_115,TEM-1,beta-lactamase_0,P62593,0.800877,NO,115,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.389,-2.535,1.146,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.0500837,0.0034337,0.800877 beta-lactamase_0_S256I,beta-lactamase_0_256,TEM-1,beta-lactamase_0,P62593,0.800891,NO,256,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.621,-3.676,2.055,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.0500837,0.00710634,0.800891 beta-lactamase_I243Y,beta-lactamase_243,TEM-1,beta-lactamase,P62593,0.800904,NO,243,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.532,-4.185,2.653,5.26886,,E,B,1.68,-1.24,2.289,,50,OHH,-1.46867,0.221079,0.00464034,0.800904 kka2_1:2_D261G,kka2_1:2_261,Kka2,kka2_1:2,P00552,0.800936,NO,261,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.708,-3.161,2.453,,0.146,G,A,0.75,-0.33,,,,HAA,-0.759333,0.295029,0.0224846,0.800936 kka2_1:4_D156M,kka2_1:4_156,Kka2,kka2_1:4,P00552,0.800976,NO,156,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.696,-4.858,3.162,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.168804,0.00926998,0.800976 beta-lactamase_G141M,beta-lactamase_141,TEM-1,beta-lactamase,P62593,0.800979,NO,141,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.828,-4.966,4.138,5.03155,0.575,T,l,0.76,-0.28,0.198,,64.69,HOO,-1.08933,0.221079,0.0012419,0.800979 kka2_1:4_T51K,kka2_1:4_51,Kka2,kka2_1:4,P00552,0.800993,NO,51,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.199,-3.076,0.877,,0.05,E,B,0.82,-0.05,13.165,13.165,63.64,BPA,-1.76767,0.168804,0.00628861,0.800993 beta-lactamase_39_S233R,beta-lactamase_39_233,TEM-1,beta-lactamase_39,P62593,0.800999,NO,233,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.886,-3.819,1.933,,0.016,E,B,0.27,-1.01,5.361,,77.62,BPO,-1.17267,0.0495842,0.00311415,0.800999 beta-lactamase_156_L218Y,beta-lactamase_156_218,TEM-1,beta-lactamase_156,P62593,0.801056,NO,218,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.391,-4.087,2.696,,,I,b,0.55,-0.53,17.202,17.202,74.48,OHH,-1.58867,0.111618,0.00618274,0.801056 beta-lactamase_0_E145N,beta-lactamase_0_145,TEM-1,beta-lactamase_0,P62593,0.801065,NO,145,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.357,-3.655,1.298,,0.545,H,A,1.04,0.79,1.199,,77.62,BAH,-2.069,0.0500837,0.00553285,0.801065 beta-lactamase_2500_G39I,beta-lactamase_2500_39,TEM-1,beta-lactamase_2500,P62593,0.801099,NO,39,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.864,-4.195,2.331,,0.701,T,L,0.29,0.47,29.926,29.926,77.62,HOH,-1.53633,0.361275,0.00487611,0.801099 beta-lactamase_0_G85D,beta-lactamase_0_85,TEM-1,beta-lactamase_0,P62593,0.801166,NO,85,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.011,-2.383,1.372,,0.805,T,l,0.29,1.7,2.25,,63.64,HOP,-1.68733,0.0500837,0.00252173,0.801166 beta-lactamase_L47E,beta-lactamase_47,TEM-1,beta-lactamase,P62593,0.801196,NO,47,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.876,-2.999,1.123,5.27297,0.007,E,B,1.07,0.2,1.244,,67.83,AHA,-1.639,0.221079,0.00439844,0.801196 beta-lactamase_P224R,beta-lactamase_224,TEM-1,beta-lactamase,P62593,0.801243,NO,224,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.893,-2.763,1.87,5.179,0.383,,B,0.99,-0.3,0.383,,74.48,HOH,-1.26433,0.221079,0.00189564,0.801243 beta-lactamase_0_Q276I,beta-lactamase_0_276,TEM-1,beta-lactamase_0,P62593,0.801404,NO,276,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.0500837,0.0191712,0.801404 kka2_1:8_R258C,kka2_1:8_258,Kka2,kka2_1:8,P00552,0.801415,NO,258,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.626,-2.089,0.463,,0.316,H,A,0.16,-0.85,5.58,,53.03,HBH,-1.25933,0.100394,0.00983174,0.801415 kka2_1:8_R258C,kka2_1:8_258,Kka2,kka2_1:8,P00552,0.801415,NO,258,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.626,-2.089,0.463,,0.316,H,A,0.16,-0.85,5.58,,53.03,HBH,-1.25933,0.100394,0.00983174,0.801415 kka2_1:2_A87H,kka2_1:2_87,Kka2,kka2_1:2,P00552,0.801447,NO,87,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.917,-3.188,1.271,,1.039,S,L,0.46,1.57,22.675,22.675,65.53,AHO,-1.822,0.295029,0.00791281,0.801447 beta-lactamase_156_Y262A,beta-lactamase_156_262,TEM-1,beta-lactamase_156,P62593,0.801455,NO,262,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.111618,0.00853516,0.801455 beta-lactamase_2500_M270Y,beta-lactamase_2500_270,TEM-1,beta-lactamase_2500,P62593,0.801469,NO,270,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.723,,,,0.422,H,A,1.59,1.15,2.029,,64.34,PHA,-1.70933,0.361275,0.00767762,0.801469 beta-lactamase_0_L160Y,beta-lactamase_0_160,TEM-1,beta-lactamase_0,P62593,0.801489,NO,160,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.977,-3.98,3.003,,0.022,,B,0.55,-0.6,0.68,,44.41,BHA,-0.936,0.0500837,0.00193775,0.801489 beta-lactamase_0_F70R,beta-lactamase_0_70,TEM-1,beta-lactamase_0,P62593,0.801564,NO,70,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.169,-4.114,2.945,,,H,A,0.58,-1.34,2.153,,63.99,PHB,-0.980667,0.0500837,0.00193499,0.801564 beta-lactamase_2500_T187V,beta-lactamase_2500_187,TEM-1,beta-lactamase_2500,P62593,0.801624,NO,187,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.401,-3.287,1.886,,0.007,H,A,0.22,-1.19,3.91,,67.48,PPH,-1.69633,0.361275,0.00491782,0.801624 beta-lactamase_A230V,beta-lactamase_230,TEM-1,beta-lactamase,P62593,0.801643,NO,230,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.154,-3.38,2.226,4.54336,0.01,E,B,0.75,-1.17,1.97,,50,HHA,-1.079,0.221079,0.00516841,0.801643 beta-lactamase_0_P60L,beta-lactamase_0_60,TEM-1,beta-lactamase_0,P62593,0.801652,NO,60,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-2.469,-2.818,0.349,,0.256,T,A,0.52,-0.56,3.653,,77.62,BOA,-1.97633,0.0500837,0.00521318,0.801652 beta-lactamase_P105T,beta-lactamase_105,TEM-1,beta-lactamase,P62593,0.801653,NO,105,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.813,-3.385,2.572,5.08236,0.226,T,A,0.98,0.8,1.154,,63.29,POH,-1.01533,0.221079,0.0011981,0.801653 kka2_1:8_K112E,kka2_1:8_112,Kka2,kka2_1:8,P00552,0.801685,NO,112,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-2.491,-3.666,1.175,,0.076,H,A,1.3,-1.37,10.58,10.58,56.06,ABH,-2.00133,0.100394,0.00645389,0.801685 kka2_1:8_K112E,kka2_1:8_112,Kka2,kka2_1:8,P00552,0.801685,NO,112,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-2.491,-3.666,1.175,,0.076,H,A,1.3,-1.37,10.58,10.58,56.06,ABH,-2.00133,0.100394,0.00645389,0.801685 kka2_1:8_V198M,kka2_1:8_198,Kka2,kka2_1:8,P00552,0.801685,NO,198,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.719,-3.281,1.562,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.100394,0.00835002,0.801685 kka2_1:8_V198M,kka2_1:8_198,Kka2,kka2_1:8,P00552,0.801685,NO,198,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.719,-3.281,1.562,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.100394,0.00835002,0.801685 beta-lactamase_625_F149G,beta-lactamase_625_149,TEM-1,beta-lactamase_625,P62593,0.80175,NO,149,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.299,-3.587,2.288,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.213352,0.00418462,0.80175 beta-lactamase_F228Q,beta-lactamase_228,TEM-1,beta-lactamase,P62593,0.801755,NO,228,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-2.342,-2.674,0.332,5.33448,0.154,E,B,1.1,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.221079,0.0046669,0.801755 PSD95pdz3_V386D,PSD95pdz3_386,PSD95pdz3,PSD95pdz3,P31016,0.80179,NO,386,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.465,-3.6,2.135,5.18836,,,,,17.5429,,,,PHP,-1.463,0.0758425,0.000184509,0.80179 kka2_1:1_G245V,kka2_1:1_245,Kka2,kka2_1:1,P00552,0.801804,NO,245,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.812,-3.749,2.937,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.520039,0.00683899,0.801804 beta-lactamase_0_R59N,beta-lactamase_0_59,TEM-1,beta-lactamase_0,P62593,0.801953,NO,59,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.345,-2.533,1.188,,0.329,S,L,1.2,-0.09,2.919,,73.08,HBO,-2.24267,0.0500837,0.00318082,0.801953 beta-lactamase_0_Y44K,beta-lactamase_0_44,TEM-1,beta-lactamase_0,P62593,0.80197,NO,44,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-2.547,-3.823,1.276,,,E,B,0.21,-0.45,1.751,,73.78,OHH,-1.86267,0.0500837,0.00426364,0.80197 PSD95pdz3_V328S,PSD95pdz3_328,PSD95pdz3,PSD95pdz3,P31016,0.80197,NO,328,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.465,-3.292,1.827,5.28275,,,,,16.8775,,,,HHO,-1.36767,0.0758425,0.000986706,0.80197 beta-lactamase_39_T158L,beta-lactamase_39_158,TEM-1,beta-lactamase_39,P62593,0.801973,NO,158,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.116,-3.303,2.187,,0.036,,B,0.22,-0.85,2.755,,69.58,HPB,-1.269,0.0495842,0.00341825,0.801973 beta-lactamase_0_P224N,beta-lactamase_0_224,TEM-1,beta-lactamase_0,P62593,0.801984,NO,224,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.893,-3.802,2.909,,0.383,,B,0.52,-0.3,3.587,,74.48,HOH,-1.26433,0.0500837,0.00189564,0.801984 Pab1_L153G,Pab1_153,Pab1,Pab1,P04147,0.801991,NO,153,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.039,-3.625,2.586,,0.46,E,A,,-0.95,,,,HHP,-1.17667,0.175299,0.000321212,0.801991 beta-lactamase_2500_P250E,beta-lactamase_2500_250,TEM-1,beta-lactamase_2500,P62593,0.802019,NO,250,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.361275,0.00550899,0.802019 beta-lactamase_2500_S51K,beta-lactamase_2500_51,TEM-1,beta-lactamase_2500,P62593,0.802019,NO,51,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.526,-3.459,1.933,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.361275,0.00504821,0.802019 beta-lactamase_2500_L150Y,beta-lactamase_2500_150,TEM-1,beta-lactamase_2500,P62593,0.802069,NO,150,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.326,-4.133,2.807,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.361275,0.00463171,0.802069 kka2_1:1_A255S,kka2_1:1_255,Kka2,kka2_1:1,P00552,0.802093,NO,255,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.715,-2.589,0.874,,0.466,H,A,0.46,-0.52,0.946,,65.53,HHH,-1.71267,0.520039,0.0126809,0.802093 beta-lactamase_L282S,beta-lactamase_282,TEM-1,beta-lactamase,P62593,0.802151,NO,282,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.586,-3.676,2.09,5.16743,0.007,H,A,1.07,0.34,31.31,31.31,63.99,PHH,-1.82367,0.221079,0.0449821,0.802151 beta-lactamase_A40V,beta-lactamase_40,TEM-1,beta-lactamase,P62593,0.802154,NO,40,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.402,-2.649,1.247,4.9697,0.155,S,B,1.2,0.21,1.714,,73.78,OHB,-1.40267,0.221079,0.00490026,0.802154 beta-lactamase_L89E,beta-lactamase_89,TEM-1,beta-lactamase,P62593,0.802181,NO,89,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.096,-3.801,2.705,5.41092,0.168,T,A,1.75,0.63,1.599,,64.34,PHO,-1.75767,0.221079,0.00207068,0.802181 PSD95pdz3_S339N,PSD95pdz3_339,PSD95pdz3,PSD95pdz3,P31016,0.80222,NO,339,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.519,-2.905,1.386,5.34493,,,,,12.2167,,,,HPH,-1.55767,0.0758425,0.00084982,0.80222 PSD95pdz3_G330D,PSD95pdz3_330,PSD95pdz3,PSD95pdz3,P31016,0.802226,NO,330,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.008,-3.15,2.142,4.68351,,,,,31.405,,,,OOA,-1.14,0.0758425,0.000962386,0.802226 beta-lactamase_0_R91I,beta-lactamase_0_91,TEM-1,beta-lactamase_0,P62593,0.802264,NO,91,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.392,-4.049,2.657,,0.444,,B,1.2,0.96,4.557,,50.35,OBB,-1.73367,0.0500837,0.00380226,0.802264 beta-lactamase_0_W288L,beta-lactamase_0_288,TEM-1,beta-lactamase_0,P62593,0.802332,NO,288,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,,,,,,,,,,,,,BHO,,0.0500837,,0.802332 kka2_1:8_W15C,kka2_1:8_15,Kka2,kka2_1:8,P00552,0.802346,NO,15,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-1.392,-4.882,3.49,,0.01,G,A,1.51,0.15,0.827,,52.27,HHH,-2.10533,0.100394,0.00585505,0.802346 kka2_1:8_W15C,kka2_1:8_15,Kka2,kka2_1:8,P00552,0.802346,NO,15,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-1.392,-4.882,3.49,,0.01,G,A,1.51,0.15,0.827,,52.27,HHH,-2.10533,0.100394,0.00585505,0.802346 beta-lactamase_W208L,beta-lactamase_208,TEM-1,beta-lactamase,P62593,0.802368,NO,208,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-0.818,-3.358,2.54,5.26277,0.067,H,A,0.99,-0.65,,,,AHH,-1.44133,0.221079,0.00126609,0.802368 kka2_1:1_P194T,kka2_1:1_194,Kka2,kka2_1:1,P00552,0.802396,NO,194,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.846,-3.444,2.598,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.520039,0.00314194,0.802396 WW_domain_Q186M,WW_domain_186,Yap65,WW_domain,P46937,0.802435,NO,186,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-1.358,-4.032,2.674,4.88854,,,,,,,,,OPB,-1.207,0.153962,0.00161546,0.802435 PSD95pdz3_F325W,PSD95pdz3_325,PSD95pdz3,PSD95pdz3,P31016,0.802525,NO,325,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.524,-4.104,2.58,5.50654,,,,,12.7236,,,,OHP,-1.314,0.0758425,0.00102273,0.802525 beta-lactamase_D48G,beta-lactamase_48,TEM-1,beta-lactamase,P62593,0.80265,NO,48,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.101,-3.259,2.158,4.89966,0.189,E,B,0.23,0.21,1.281,,50.35,HAH,-1.62467,0.221079,0.0027273,0.80265 beta-lactamase_0_I54D,beta-lactamase_0_54,TEM-1,beta-lactamase_0,P62593,0.802716,NO,54,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-2.838,-3.732,0.894,,0.669,E,B,0.48,-0.14,0.541,,73.78,BHH,-2.337,0.0500837,0.00403589,0.802716 kka2_1:8_P76I,kka2_1:8_76,Kka2,kka2_1:8,P00552,0.802736,NO,76,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.449,-3.871,2.422,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.100394,0.00625685,0.802736 kka2_1:8_P76I,kka2_1:8_76,Kka2,kka2_1:8,P00552,0.802736,NO,76,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.449,-3.871,2.422,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.100394,0.00625685,0.802736 beta-lactamase_39_Y44E,beta-lactamase_39_44,TEM-1,beta-lactamase_39,P62593,0.802855,NO,44,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-2.547,-3.866,1.319,,,E,B,0.21,-0.45,2.683,,73.78,OHH,-1.86267,0.0495842,0.00426364,0.802855 kka2_1:4_E182K,kka2_1:4_182,Kka2,kka2_1:4,P00552,0.802874,NO,182,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.516,-3.472,1.956,,0.326,.,B,1.04,0.75,4.755,,65.53,OAA,-1.806,0.168804,0.00641548,0.802874 beta-lactamase_P105Q,beta-lactamase_105,TEM-1,beta-lactamase,P62593,0.802918,NO,105,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.813,-3.897,3.084,5.08236,0.226,T,A,0.98,0.8,1.154,,63.29,POH,-1.01533,0.221079,0.0011981,0.802918 beta-lactamase_0_L28Q,beta-lactamase_0_28,TEM-1,beta-lactamase_0,P62593,0.802936,NO,28,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.579,-2.97,1.391,,0.277,H,A,0.55,-0.16,9.35,9.35,93.01,PHH,-2.11333,0.0500837,0.00359321,0.802936 kka2_1:8_R89L,kka2_1:8_89,Kka2,kka2_1:8,P00552,0.802975,NO,89,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.548,-3.591,2.043,,0.209,E,B,1.2,1.41,25.3,25.3,64.39,OBA,-1.89867,0.100394,0.00524373,0.802975 kka2_1:8_R89L,kka2_1:8_89,Kka2,kka2_1:8,P00552,0.802975,NO,89,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.548,-3.591,2.043,,0.209,E,B,1.2,1.41,25.3,25.3,64.39,OBA,-1.89867,0.100394,0.00524373,0.802975 beta-lactamase_R159E,beta-lactamase_159,TEM-1,beta-lactamase,P62593,0.803038,NO,159,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-0.94,-3.241,2.301,5.64971,0.316,,B,0.68,-0.55,1.172,,64.34,PBH,-1.011,0.221079,0.00108472,0.803038 beta-lactamase_0_L146P,beta-lactamase_0_146,TEM-1,beta-lactamase_0,P62593,0.803053,NO,146,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.462,-4.216,2.754,,0.007,H,A,0.55,-0.56,2.051,,64.69,AHP,-1.656,0.0500837,0.00474542,0.803053 Pab1_T145R,Pab1_145,Pab1,Pab1,P04147,0.803061,NO,145,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.067,-3.525,2.458,,0.237,H,A,0.3,0.69,,,,APH,-1.135,0.175299,0.000331088,0.803061 beta-lactamase_2500_M270P,beta-lactamase_2500_270,TEM-1,beta-lactamase_2500,P62593,0.803104,NO,270,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.723,,,,0.422,H,A,1.59,1.15,2.029,,64.34,PHA,-1.70933,0.361275,0.00767762,0.803104 kka2_1:4_A108Y,kka2_1:4_108,Kka2,kka2_1:4,P00552,0.803157,NO,108,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.061,-4.432,2.371,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.168804,0.00751209,0.803157 WW_domain_G185N,WW_domain_185,Yap65,WW_domain,P46937,0.803211,NO,185,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.861,-3.225,2.364,6.22337,,,,,,,,,POP,-1.194,0.153962,0.00199178,0.803211 beta-lactamase_P249L,beta-lactamase_249,TEM-1,beta-lactamase,P62593,0.803268,NO,249,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.312,-2.774,1.462,5.10655,0.256,S,B,0.99,0.04,0.479,,72.73,OOA,-1.81367,0.221079,0.00220169,0.803268 beta-lactamase_2500_A211I,beta-lactamase_2500_211,TEM-1,beta-lactamase_2500,P62593,0.803286,NO,211,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.896,-4.033,2.137,,0.369,T,A,0.46,-0.69,2.061,,77.62,AHA,-1.94633,0.361275,0.00648183,0.803286 beta-lactamase_0_S96V,beta-lactamase_0_96,TEM-1,beta-lactamase_0,P62593,0.803307,NO,96,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.27,-3.642,1.372,,0.368,,b,0.27,0.39,2.516,,73.78,HPP,-2.019,0.0500837,0.00551835,0.803307 Pab1_I137Y,Pab1_137,Pab1,Pab1,P04147,0.803332,NO,137,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.212,-3.755,2.543,,0.068,,B,0.77,0.35,,,,AHA,-1.314,0.175299,0.000342224,0.803332 kka2_1:8_D90P,kka2_1:8_90,Kka2,kka2_1:8,P00552,0.803385,NO,90,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.459,-4.102,1.643,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.100394,0.00583842,0.803385 kka2_1:8_D90P,kka2_1:8_90,Kka2,kka2_1:8,P00552,0.803385,NO,90,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.459,-4.102,1.643,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.100394,0.00583842,0.803385 Pab1_K166E,Pab1_166,Pab1,Pab1,P04147,0.803388,NO,166,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.262,-2.95,1.688,,0.299,,l,,0,,,,PBO,-1.21033,0.175299,0.0011038,0.803388 beta-lactamase_0_L197R,beta-lactamase_0_197,TEM-1,beta-lactamase_0,P62593,0.803481,NO,197,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.853,-3.93,3.077,,0.007,S,B,0.55,0.33,1.087,,60.14,HHP,-1.833,0.0500837,0.00144602,0.803481 kka2_1:1_R239G,kka2_1:1_239,Kka2,kka2_1:1,P00552,0.803503,NO,239,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.949,-2.877,-0.072,,0.15,H,A,1.2,-0.31,0.477,,71.59,ABH,-2.23,0.520039,0.00835326,0.803503 beta-lactamase_2500_A268W,beta-lactamase_2500_268,TEM-1,beta-lactamase_2500,P62593,0.803511,NO,268,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.361275,0.0102525,0.803511 beta-lactamase_2500_L284F,beta-lactamase_2500_284,TEM-1,beta-lactamase_2500,P62593,0.803547,NO,284,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.361275,0.0686156,0.803547 kka2_1:2_A64S,kka2_1:2_64,Kka2,kka2_1:2,P00552,0.803598,NO,64,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.496,-3.437,1.941,,0.039,H,A,0.46,-0.57,14.509,14.509,56.06,AHH,-1.334,0.295029,0.00705578,0.803598 beta-lactamase_2500_T107L,beta-lactamase_2500_107,TEM-1,beta-lactamase_2500,P62593,0.803605,NO,107,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.117,-3.237,2.12,,,G,A,0.22,-0.06,2.686,,67.83,HPA,-1.265,0.361275,0.00239347,0.803605 kka2_1:1_A168E,kka2_1:1_168,Kka2,kka2_1:1,P00552,0.803612,NO,168,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.989,-2.167,0.178,,0.67,H,A,0.46,0.15,25.546,25.546,64.39,OHA,-2.12933,0.520039,0.00806773,0.803612 Pab1_D138K,Pab1_138,Pab1,Pab1,P04147,0.803637,NO,138,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.128,-3.197,2.069,,0.427,,B,,-0.03,,,,HAP,-1.13967,0.175299,0.000567877,0.803637 kka2_1:8_A224L,kka2_1:8_224,Kka2,kka2_1:8,P00552,0.803693,NO,224,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.977,-3.204,2.227,,,H,A,0.46,-1.26,0.357,,63.64,HHP,-1.41033,0.100394,0.00352047,0.803693 kka2_1:8_A224L,kka2_1:8_224,Kka2,kka2_1:8,P00552,0.803693,NO,224,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.977,-3.204,2.227,,,H,A,0.46,-1.26,0.357,,63.64,HHP,-1.41033,0.100394,0.00352047,0.803693 beta-lactamase_2500_S221P,beta-lactamase_2500_221,TEM-1,beta-lactamase_2500,P62593,0.803743,NO,221,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.754,-3.814,2.06,,0.624,H,A,0.27,-0.2,1.971,,74.48,BPH,-1.59967,0.361275,0.0046094,0.803743 kka2_1:8_V97L,kka2_1:8_97,Kka2,kka2_1:8,P00552,0.803783,NO,97,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.453,-1.404,-0.049,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.100394,0.00737869,0.803783 kka2_1:8_V97L,kka2_1:8_97,Kka2,kka2_1:8,P00552,0.803783,NO,97,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.453,-1.404,-0.049,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.100394,0.00737869,0.803783 WW_domain_A175E,WW_domain_175,Yap65,WW_domain,P46937,0.803872,NO,175,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.631,-3.173,1.542,6.69537,,,,,,6.257,,83.93,OHO,-1.30033,0.153962,0.00326874,0.803872 kka2_1:2_P12R,kka2_1:2_12,Kka2,kka2_1:2,P00552,0.803946,NO,12,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.853,-3.931,3.078,,,.,B,0.52,1.25,0.261,,48.11,POH,-1.80767,0.295029,0.00500011,0.803946 beta-lactamase_2500_A278T,beta-lactamase_2500_278,TEM-1,beta-lactamase_2500,P62593,0.804027,NO,278,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.361275,0.0310297,0.804027 beta-lactamase_G85W,beta-lactamase_85,TEM-1,beta-lactamase,P62593,0.804082,NO,85,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.011,-5.288,4.277,5.58951,0.805,T,l,0.23,1.7,1.468,,63.64,HOP,-1.68733,0.221079,0.00252173,0.804082 kka2_1:8_P179W,kka2_1:8_179,Kka2,kka2_1:8,P00552,0.804085,NO,179,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.974,-5.539,4.565,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.100394,0.00298346,0.804085 kka2_1:8_P179W,kka2_1:8_179,Kka2,kka2_1:8,P00552,0.804085,NO,179,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.974,-5.539,4.565,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.100394,0.00298346,0.804085 beta-lactamase_0_I45W,beta-lactamase_0_45,TEM-1,beta-lactamase_0,P62593,0.804089,NO,45,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-2.421,-5.294,2.873,,,E,B,0.48,-0.3,1.375,,77.62,HHA,-2.30267,0.0500837,0.00452842,0.804089 beta-lactamase_156_L100P,beta-lactamase_156_100,TEM-1,beta-lactamase_156,P62593,0.804099,NO,100,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.218,-4.169,2.951,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.111618,0.00413885,0.804099 beta-lactamase_0_A124Q,beta-lactamase_0_124,TEM-1,beta-lactamase_0,P62593,0.804106,NO,124,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.181,-4.004,2.823,,,H,A,0.46,-0.9,1.876,,64.34,HHH,-1.152,0.0500837,0.00481399,0.804106 beta-lactamase_2500_V106S,beta-lactamase_2500_106,TEM-1,beta-lactamase_2500,P62593,0.804173,NO,106,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.218,-3.705,2.487,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.361275,0.00304168,0.804173 beta-lactamase_0_H287W,beta-lactamase_0_287,TEM-1,beta-lactamase_0,P62593,0.804186,NO,287,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,,,,,,,,,,,,,BBH,-1.111,0.0500837,,0.804186 PSD95pdz3_V386K,PSD95pdz3_386,PSD95pdz3,PSD95pdz3,P31016,0.804208,NO,386,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.465,-3.364,1.899,5.18836,,,,,17.5429,,,,PHP,-1.463,0.0758425,0.000184509,0.804208 beta-lactamase_39_M127P,beta-lactamase_39_127,TEM-1,beta-lactamase_39,P62593,0.804224,NO,127,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-2.251,-4.144,1.893,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.0495842,0.00437927,0.804224 beta-lactamase_I283R,beta-lactamase_283,TEM-1,beta-lactamase,P62593,0.804224,NO,283,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.638,-4.12,2.482,5.4178,0.165,H,A,1.23,0.04,1.576,,69.23,HHB,-1.735,0.221079,0.0429138,0.804224 beta-lactamase_39_R91P,beta-lactamase_39_91,TEM-1,beta-lactamase_39,P62593,0.804315,NO,91,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.392,-3.876,2.484,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.0495842,0.00380226,0.804315 beta-lactamase_39_K32P,beta-lactamase_39_32,TEM-1,beta-lactamase_39,P62593,0.804358,NO,32,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.984,-3.947,1.963,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.0495842,0.00401283,0.804358 beta-lactamase_0_T69H,beta-lactamase_0_69,TEM-1,beta-lactamase_0,P62593,0.804372,NO,69,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-0.973,-4.716,3.743,,,G,A,0.22,-1.24,0.505,,93.01,PPH,-1.01833,0.0500837,0.00127498,0.804372 beta-lactamase_39_G76Q,beta-lactamase_39_76,TEM-1,beta-lactamase_39,P62593,0.804375,NO,76,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.189,-4.074,2.885,,,H,A,0.29,-0.67,2.145,,67.83,OOH,-1.22267,0.0495842,0.00476637,0.804375 beta-lactamase_0_H287T,beta-lactamase_0_287,TEM-1,beta-lactamase_0,P62593,0.8044,NO,287,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,,,,,,,,,,,,,BBH,-1.111,0.0500837,,0.8044 beta-lactamase_0_L284F,beta-lactamase_0_284,TEM-1,beta-lactamase_0,P62593,0.804507,NO,284,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.981,,,,0.848,H,A,2.89,0.67,4.544,,77.62,PHH,-1.82133,0.0500837,0.0686156,0.804507 beta-lactamase_156_E195F,beta-lactamase_156_195,TEM-1,beta-lactamase_156,P62593,0.804561,NO,195,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.186,-4.475,2.289,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.111618,0.00496565,0.804561 beta-lactamase_2500_E62H,beta-lactamase_2500_62,TEM-1,beta-lactamase_2500,P62593,0.804585,NO,62,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.193,-4.429,3.236,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.361275,0.00264802,0.804585 PSD95pdz3_R318E,PSD95pdz3_318,PSD95pdz3,PSD95pdz3,P31016,0.804619,NO,318,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.582,-2.897,1.315,4.94876,,,,,17.5609,,,,BBO,-1.40567,0.0758425,0.00110471,0.804619 beta-lactamase_2500_R176S,beta-lactamase_2500_176,TEM-1,beta-lactamase_2500,P62593,0.804629,NO,176,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-0.863,-3.386,2.523,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.361275,0.00105554,0.804629 beta-lactamase_L191T,beta-lactamase_191,TEM-1,beta-lactamase,P62593,0.804632,NO,191,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.087,-3.447,2.36,5.72226,,H,A,1.07,0.09,1.23,,63.29,BHH,-1.445,0.221079,0.00263549,0.804632 kka2_1:8_S104A,kka2_1:8_104,Kka2,kka2_1:8,P00552,0.804634,NO,104,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.436,-3.053,1.617,,0.536,T,A,0.27,-1.11,1.689,,63.64,HPP,-1.91433,0.100394,0.00555207,0.804634 kka2_1:8_S104A,kka2_1:8_104,Kka2,kka2_1:8,P00552,0.804634,NO,104,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.436,-3.053,1.617,,0.536,T,A,0.27,-1.11,1.689,,63.64,HPP,-1.91433,0.100394,0.00555207,0.804634 beta-lactamase_39_T131D,beta-lactamase_39_131,TEM-1,beta-lactamase_39,P62593,0.804656,NO,131,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.328,-3.605,2.277,,,H,A,0.22,-0.69,3.306,,67.48,PPH,-1.00867,0.0495842,0.00345886,0.804656 beta-lactamase_0_K213I,beta-lactamase_0_213,TEM-1,beta-lactamase_0,P62593,0.804657,NO,213,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.81,-4.142,2.332,,0.67,,A,2.34,0.29,3.015,,67.83,ABH,-1.57767,0.0500837,0.00610411,0.804657 Pab1_K156M,Pab1_156,Pab1,Pab1,P04147,0.804807,NO,156,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.083,-4.297,3.214,,0.406,E,B,1.82,-0.26,,,,PBH,-1.58167,0.175299,0.000316767,0.804807 beta-lactamase_0_G216N,beta-lactamase_0_216,TEM-1,beta-lactamase_0,P62593,0.804881,NO,216,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.477,-2.771,1.294,,0.437,I,A,0.29,-0.58,0.834,,74.48,HOO,-1.68067,0.0500837,0.00639568,0.804881 kka2_1:1_L7K,kka2_1:1_7,Kka2,kka2_1:1,P00552,0.804948,NO,7,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.926,-3.481,1.555,,,,,,,18.934,18.934,71.59,OHB,-2.12333,0.520039,0.00269456,0.804948 kka2_1:2_A215S,kka2_1:2_215,Kka2,kka2_1:2,P00552,0.805139,NO,215,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.968,-1.873,0.905,,0.039,E,B,0.46,-0.59,2.137,,50.38,HHA,-1.00467,0.295029,0.00529129,0.805139 kka2_1:2_C209G,kka2_1:2_209,Kka2,kka2_1:2,P00552,0.805168,NO,209,C,G,CG,Special,Special,5.07,3.29388,-1.77612,159,121,75,-46,108.5,60.1,-48.4,-0.906,-3.655,2.749,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.295029,0.00260862,0.805168 kka2_1:8_M197R,kka2_1:8_197,Kka2,kka2_1:8,P00552,0.805183,NO,197,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.707,-4.083,2.376,,0.121,E,B,1.59,-1.19,4.408,,65.53,HHH,-1.847,0.100394,0.00921295,0.805183 kka2_1:8_M197R,kka2_1:8_197,Kka2,kka2_1:8,P00552,0.805183,NO,197,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.707,-4.083,2.376,,0.121,E,B,1.59,-1.19,4.408,,65.53,HHH,-1.847,0.100394,0.00921295,0.805183 beta-lactamase_0_W227S,beta-lactamase_0_227,TEM-1,beta-lactamase_0,P62593,0.805214,NO,227,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-0.982,-3.768,2.786,,0.272,,B,0.47,-0.29,3.782,,74.48,OHH,-1.595,0.0500837,0.00226019,0.805214 beta-lactamase_2500_P250S,beta-lactamase_2500_250,TEM-1,beta-lactamase_2500,P62593,0.805226,NO,250,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.361275,0.00550899,0.805226 beta-lactamase_2500_W163D,beta-lactamase_2500_163,TEM-1,beta-lactamase_2500,P62593,0.805226,NO,163,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-1.843,-3.903,2.06,,0.467,,B,0.47,-0.5,32.624,32.624,63.99,BHA,-1.269,0.361275,0.00418955,0.805226 kka2_1:4_L152D,kka2_1:4_152,Kka2,kka2_1:4,P00552,0.805321,NO,152,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.521,-3.958,2.437,,0.547,,A,1.59,1.36,2.318,,63.64,OHH,-1.162,0.168804,0.00674868,0.805321 kka2_1:4_G99C,kka2_1:4_99,Kka2,kka2_1:4,P00552,0.805369,NO,99,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.596,-5.115,4.519,,0.368,S,g,0.29,-0.87,,,,OOP,-1.63067,0.168804,0.00186055,0.805369 beta-lactamase_0_S96M,beta-lactamase_0_96,TEM-1,beta-lactamase_0,P62593,0.805403,NO,96,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.27,-3.49,1.22,,0.368,,b,0.27,0.39,2.516,,73.78,HPP,-2.019,0.0500837,0.00551835,0.805403 kka2_1:2_E231M,kka2_1:2_231,Kka2,kka2_1:2,P00552,0.805437,NO,231,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.002,-4.813,2.811,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.295029,0.00732383,0.805437 beta-lactamase_2500_G216T,beta-lactamase_2500_216,TEM-1,beta-lactamase_2500,P62593,0.805445,NO,216,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.477,-3.599,2.122,,0.437,I,A,0.29,-0.58,1.983,,74.48,HOO,-1.68067,0.361275,0.00639568,0.805445 beta-lactamase_E119K,beta-lactamase_119,TEM-1,beta-lactamase,P62593,0.805471,NO,119,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.412,-3.343,1.931,5.33349,0.358,H,A,1.52,0.51,1.983,,63.99,BAH,-1.623,0.221079,0.00386966,0.805471 beta-lactamase_2500_I285C,beta-lactamase_2500_285,TEM-1,beta-lactamase_2500,P62593,0.805554,NO,285,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.361275,0.101555,0.805554 beta-lactamase_625_S233P,beta-lactamase_625_233,TEM-1,beta-lactamase_625,P62593,0.805595,NO,233,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.886,-2.778,0.892,,0.016,E,B,0.27,-1.01,1.773,,77.62,BPO,-1.17267,0.213352,0.00311415,0.805595 beta-lactamase_F149N,beta-lactamase_149,TEM-1,beta-lactamase,P62593,0.805618,NO,149,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.299,-4.055,2.756,5.54789,0.195,H,A,1.1,0.11,1.863,,63.99,HHH,-1.46067,0.221079,0.00418462,0.805618 beta-lactamase_625_A230L,beta-lactamase_625_230,TEM-1,beta-lactamase_625,P62593,0.80566,NO,230,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.154,-3.416,2.262,,0.01,E,B,0.46,-1.17,0.777,,50,HHA,-1.079,0.213352,0.00516841,0.80566 kka2_1:1_L241R,kka2_1:1_241,Kka2,kka2_1:1,P00552,0.805684,NO,241,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.158,-4.121,2.963,,0.08,H,A,0.55,-0.82,1.685,,63.26,HHH,-1.58533,0.520039,0.0117299,0.805684 gb1_L238C,gb1_238,gb1,gb1,P06654,0.80573,NO,238,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-2.98,-4.825,1.845,,,,,,,0.504,,45.54,PHB,-2.58633,0.177985,0.00205885,0.80573 kka2_1:4_L158Q,kka2_1:4_158,Kka2,kka2_1:4,P00552,0.805755,NO,158,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.947,-4.338,2.391,,0.095,,B,1.59,0.77,7.588,,63.64,AHA,-1.25333,0.168804,0.00529068,0.805755 beta-lactamase_39_T179M,beta-lactamase_39_179,TEM-1,beta-lactamase_39,P62593,0.805809,NO,179,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.085,-4.564,3.479,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.0495842,0.00226045,0.805809 beta-lactamase_0_D161Y,beta-lactamase_0_161,TEM-1,beta-lactamase_0,P62593,0.805829,NO,161,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.891,-4.387,3.496,,0.341,,A,0.75,-0.52,0.795,,61.19,HAB,-0.961333,0.0500837,0.000897697,0.805829 kka2_1:4_A191W,kka2_1:4_191,Kka2,kka2_1:4,P00552,0.805861,NO,191,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.831,-5.414,4.583,,,.,b,0.46,-0.94,2.046,,50,AHO,-0.868667,0.168804,0.00338807,0.805861 beta-lactamase_T27P,beta-lactamase_27,TEM-1,beta-lactamase,P62593,0.805887,NO,27,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.905,-1.921,0.016,5.39752,0.007,H,A,0.69,-0.37,0.745,,93.01,APH,-1.97933,0.221079,0.00306559,0.805887 PSD95pdz3_V362F,PSD95pdz3_362,PSD95pdz3,PSD95pdz3,P31016,0.805896,NO,362,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.465,-3.524,2.059,4.99436,,,,,19.6443,,,,PHP,-1.46467,0.0758425,0.000538527,0.805896 beta-lactamase_R81W,beta-lactamase_81,TEM-1,beta-lactamase,P62593,0.805943,NO,81,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.466,-5.415,3.949,5.12166,0.218,H,A,0.68,1.66,1.236,,50,PBH,-1.60667,0.221079,0.00499763,0.805943 kka2_1:8_D227Y,kka2_1:8_227,Kka2,kka2_1:8,P00552,0.805985,NO,227,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.758,-4.295,2.537,,0.128,H,A,0.75,-0.63,0.281,,56.06,BAH,-1.43067,0.100394,0.00745029,0.805985 kka2_1:8_D227Y,kka2_1:8_227,Kka2,kka2_1:8,P00552,0.805985,NO,227,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.758,-4.295,2.537,,0.128,H,A,0.75,-0.63,0.281,,56.06,BAH,-1.43067,0.100394,0.00745029,0.805985 beta-lactamase_S240H,beta-lactamase_240,TEM-1,beta-lactamase,P62593,0.806013,NO,240,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.537,-4.644,3.107,4.75024,,,B,0.74,-0.74,0.357,,65.38,OPB,-1.263,0.221079,0.00591201,0.806013 kka2_1:1_H139N,kka2_1:1_139,Kka2,kka2_1:1,P00552,0.806072,NO,139,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-2.809,-2.773,-0.036,,0.471,H,A,0.17,0.68,1.153,,63.64,BBB,-2.22,0.520039,0.00734779,0.806072 kka2_1:2_R18V,kka2_1:2_18,Kka2,kka2_1:2,P00552,0.806101,NO,18,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.055,-3.089,1.034,,0.474,T,A,1.2,0.54,8.405,8.405,71.59,ABH,-1.821,0.295029,0.00724065,0.806101 kka2_1:2_M197V,kka2_1:2_197,Kka2,kka2_1:2,P00552,0.806159,NO,197,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.707,-2.226,0.519,,0.121,E,B,0.55,-1.19,2.097,,65.53,HHH,-1.847,0.295029,0.00921295,0.806159 beta-lactamase_0_H110M,beta-lactamase_0_110,TEM-1,beta-lactamase_0,P62593,0.806178,NO,110,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-1.706,-3.324,1.618,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.0500837,0.00441499,0.806178 PSD95pdz3_I327V,PSD95pdz3_327,PSD95pdz3,PSD95pdz3,P31016,0.806189,NO,327,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.63,-2.085,0.455,5.7413,,,,,14.0388,,,,PHH,-1.50167,0.0758425,0.000998774,0.806189 kka2_1:4_A222G,kka2_1:4_222,Kka2,kka2_1:4,P00552,0.806243,NO,222,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.725,-2.936,2.211,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.168804,0.00207657,0.806243 beta-lactamase_0_L219M,beta-lactamase_0_219,TEM-1,beta-lactamase_0,P62593,0.806255,NO,219,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.313,-3.006,1.693,,,I,A,0.55,-0.51,6.513,6.513,74.48,HHB,-1.21533,0.0500837,0.00664345,0.806255 kka2_1:2_K138S,kka2_1:2_138,Kka2,kka2_1:2,P00552,0.806255,NO,138,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-2.5,-2.62,0.12,,0.594,H,A,2.34,0.98,21.038,21.038,71.59,HBB,-2.48833,0.295029,0.00628542,0.806255 PSD95pdz3_D357G,PSD95pdz3_357,PSD95pdz3,PSD95pdz3,P31016,0.80627,NO,357,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.264,-2.815,1.551,5.22306,,,,,10.975,,,,OAP,-1.32367,0.0758425,0.000609015,0.80627 kka2_1:8_I141L,kka2_1:8_141,Kka2,kka2_1:8,P00552,0.806282,NO,141,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.495,-1.454,-0.041,,0.068,H,A,1.52,-0.01,2.144,,92.05,BHA,-1.689,0.100394,0.00744745,0.806282 kka2_1:8_I141L,kka2_1:8_141,Kka2,kka2_1:8,P00552,0.806282,NO,141,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.495,-1.454,-0.041,,0.068,H,A,1.52,-0.01,2.144,,92.05,BHA,-1.689,0.100394,0.00744745,0.806282 beta-lactamase_2500_V82S,beta-lactamase_2500_82,TEM-1,beta-lactamase_2500,P62593,0.806329,NO,82,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.325,-3.501,2.176,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.361275,0.00397046,0.806329 kka2_1:2_L165P,kka2_1:2_165,Kka2,kka2_1:2,P00552,0.806341,NO,165,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-2.453,-3.229,0.776,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.295029,0.00801161,0.806341 kka2_1:4_D127H,kka2_1:4_127,Kka2,kka2_1:4,P00552,0.806349,NO,127,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.364,-4.683,3.319,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.168804,0.00660501,0.806349 E1_Ubiquitin_I44N,E1_Ubiquitin_44,Uba1,E1_Ubiquitin,P0CG63,0.806366,NO,44,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.432,-3.784,2.352,,,E,B,0.27,-1.17,4.57,,78.74,HHH,-1.25633,0.18783,0.00209731,0.806366 beta-lactamase_L79V,beta-lactamase_79,TEM-1,beta-lactamase,P62593,0.806409,NO,79,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.842,-2.879,2.037,4.98681,0.007,H,A,1.07,-0.16,0.823,,50.35,HHP,-1.44333,0.221079,0.000947397,0.806409 beta-lactamase_P105M,beta-lactamase_105,TEM-1,beta-lactamase,P62593,0.806409,NO,105,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.813,-4.702,3.889,5.08236,0.226,T,A,0.98,0.8,1.154,,63.29,POH,-1.01533,0.221079,0.0011981,0.806409 beta-lactamase_0_G265T,beta-lactamase_0_265,TEM-1,beta-lactamase_0,P62593,0.806415,NO,265,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.0500837,0.00811926,0.806415 Ubiquitin_A46I,Ubiquitin_46,Uba1,Ubiquitin,P0CG48,0.806452,NO,46,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.77,-3.784,2.014,5.38761,0.398,T,L,2.34,-0.8,6.506,,51.09,HHO,-1.505,0.205827,0.000581142,0.806452 Ubiquitin_D32I,Ubiquitin_32,Uba1,Ubiquitin,P0CG48,0.806452,NO,32,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.451,-3.987,2.536,4.96502,0.835,H,A,,1.4,,,,PAB,-1.47067,0.205827,0.000758819,0.806452 Ubiquitin_D58R,Ubiquitin_58,Uba1,Ubiquitin,P0CG48,0.806452,NO,58,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.622,-3.972,2.35,5.06391,0.457,G,A,,-0.54,,,,PAH,-1.60267,0.205827,0.000639847,0.806452 Ubiquitin_D58Y,Ubiquitin_58,Uba1,Ubiquitin,P0CG48,0.806452,NO,58,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.622,-2.54,0.918,5.06391,0.457,G,A,,-0.54,,,,PAH,-1.60267,0.205827,0.000639847,0.806452 Ubiquitin_I23Q,Ubiquitin_23,Uba1,Ubiquitin,P0CG48,0.806452,NO,23,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.325,-4.247,2.922,4.67534,,H,A,0.01,-0.93,0.515,,52.12,PHA,-1.54033,0.205827,0.000621252,0.806452 Ubiquitin_Q40R,Ubiquitin_40,Uba1,Ubiquitin,P0CG48,0.806452,NO,40,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-1.752,-2.866,1.114,4.7807,0.387,G,A,,0.03,,,,APP,-1.62433,0.205827,0.000619089,0.806452 beta-lactamase_0_S68W,beta-lactamase_0_68,TEM-1,beta-lactamase_0,P62593,0.806542,NO,68,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-0.913,-5.371,4.458,,0.064,G,A,0.27,-1.03,1.441,,64.69,HPP,-1.37233,0.0500837,0.000800065,0.806542 kka2_1:2_V80T,kka2_1:2_80,Kka2,kka2_1:2,P00552,0.806569,NO,80,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.144,-3.381,2.237,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.295029,0.00488211,0.806569 kka2_1:2_D154F,kka2_1:2_154,Kka2,kka2_1:2,P00552,0.806612,NO,154,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.876,-4.375,3.499,,0.457,,b,0.29,1.48,3.631,,52.65,HAP,-1.52467,0.295029,0.00292633,0.806612 kka2_1:1_G95C,kka2_1:1_95,Kka2,kka2_1:1,P00552,0.806618,NO,95,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-2.403,-5.049,2.646,,0.126,E,B,0.29,-0.74,7.822,,71.59,HOA,-2.198,0.520039,0.00743616,0.806618 beta-lactamase_P224Q,beta-lactamase_224,TEM-1,beta-lactamase,P62593,0.806659,NO,224,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.893,-3.868,2.975,5.179,0.383,,B,0.99,-0.3,0.383,,74.48,HOH,-1.26433,0.221079,0.00189564,0.806659 beta-lactamase_0_N274W,beta-lactamase_0_274,TEM-1,beta-lactamase_0,P62593,0.806671,NO,274,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.0500837,0.0110418,0.806671 kka2_1:1_S40R,kka2_1:1_40,Kka2,kka2_1:1,P00552,0.806696,NO,40,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.645,-2.494,-0.151,,0.32,E,B,0.27,-0.9,25.997,25.997,71.59,HPH,-1.91567,0.520039,0.00693477,0.806696 beta-lactamase_0_I54K,beta-lactamase_0_54,TEM-1,beta-lactamase_0,P62593,0.806718,NO,54,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-2.838,-2.926,0.088,,0.669,E,B,0.48,-0.14,0.541,,73.78,BHH,-2.337,0.0500837,0.00403589,0.806718 beta-lactamase_0_R162Y,beta-lactamase_0_162,TEM-1,beta-lactamase_0,P62593,0.80674,NO,162,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.016,-4.207,3.191,,0.124,S,B,1.2,-0.37,1.026,,64.69,ABH,-1.25,0.0500837,0.000561334,0.80674 Pab1_K156V,Pab1_156,Pab1,Pab1,P04147,0.806774,NO,156,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.083,-3.346,2.263,,0.406,E,B,1.82,-0.26,,,,PBH,-1.58167,0.175299,0.000316767,0.806774 gb1_E282W,gb1_282,gb1,gb1,P06654,0.806803,NO,282,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.318,-5.162,3.844,,,,,,,1.075,,35.71,PAO,-1.573,0.177985,0.00209643,0.806803 beta-lactamase_0_T112H,beta-lactamase_0_112,TEM-1,beta-lactamase_0,P62593,0.806813,NO,112,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.186,-4.734,2.548,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.0500837,0.00531334,0.806813 kka2_1:4_Q136Y,kka2_1:4_136,Kka2,kka2_1:4,P00552,0.806854,NO,136,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-3.021,-4.291,1.27,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.168804,0.00624149,0.806854 kka2_1:2_G164C,kka2_1:2_164,Kka2,kka2_1:2,P00552,0.806868,NO,164,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.869,-5.135,4.266,,0.862,T,l,0.75,1.45,1.539,,64.39,POH,-1.828,0.295029,0.00442091,0.806868 beta-lactamase_39_D212T,beta-lactamase_39_212,TEM-1,beta-lactamase_39,P62593,0.80687,NO,212,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.624,-2.54,0.916,,0.037,,b,0.75,-0.58,10.748,10.748,74.48,HAB,-1.77667,0.0495842,0.00644302,0.80687 beta-lactamase_2500_A183W,beta-lactamase_2500_183,TEM-1,beta-lactamase_2500,P62593,0.806929,NO,183,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.231,-5.466,4.235,,0.155,H,A,0.46,-0.91,12.189,,77.62,HHH,-1.53367,0.361275,0.00296631,0.806929 beta-lactamase_2500_P143H,beta-lactamase_2500_143,TEM-1,beta-lactamase_2500,P62593,0.806946,NO,143,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.967,-4.789,3.822,,0.075,H,A,0.52,-0.37,0.479,,66.78,OOB,-1.354,0.361275,0.00114551,0.806946 PSD95pdz3_R318D,PSD95pdz3_318,PSD95pdz3,PSD95pdz3,P31016,0.80695,NO,318,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.582,-3.375,1.793,4.94876,,,,,17.5609,,,,BBO,-1.40567,0.0758425,0.00110471,0.80695 beta-lactamase_R241K,beta-lactamase_241,TEM-1,beta-lactamase,P62593,0.806978,NO,241,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.433,-3.194,1.761,5.02621,0.094,E,B,0.68,-0.16,1.327,,50,PBO,-1.42967,0.221079,0.00452736,0.806978 kka2_1:1_W236C,kka2_1:1_236,Kka2,kka2_1:1,P00552,0.80703,NO,236,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-1.363,-3.273,1.91,,0.303,H,A,1.51,-0.76,12.263,12.263,48.48,AHH,-1.81267,0.520039,0.0088796,0.80703 beta-lactamase_0_R91S,beta-lactamase_0_91,TEM-1,beta-lactamase_0,P62593,0.807053,NO,91,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.392,-3.342,1.95,,0.444,,B,1.2,0.96,4.557,,50.35,OBB,-1.73367,0.0500837,0.00380226,0.807053 beta-lactamase_V21N,beta-lactamase_21,TEM-1,beta-lactamase,P62593,0.80708,NO,21,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.873,-3.89,2.017,,,,,,,0.688,,93.01,OHH,-2.09633,0.221079,0.0028612,0.80708 PSD95pdz3_L353Y,PSD95pdz3_353,PSD95pdz3,PSD95pdz3,P31016,0.80708,NO,353,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.347,-3.619,2.272,5.81136,,,,,17.3525,,,,AHB,-1.50533,0.0758425,0.000664742,0.80708 beta-lactamase_L38K,beta-lactamase_38,TEM-1,beta-lactamase,P62593,0.807125,NO,38,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.343,-3.749,2.406,5.23728,0.088,H,A,1.75,0.2,1.986,,64.34,PHO,-1.78033,0.221079,0.00373244,0.807125 kka2_1:2_V46R,kka2_1:2_46,Kka2,kka2_1:2,P00552,0.807145,NO,46,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-2.62,-2.74,0.12,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.295029,0.00631301,0.807145 kka2_1:4_T51Y,kka2_1:4_51,Kka2,kka2_1:4,P00552,0.807157,NO,51,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.199,-4.283,2.084,,0.05,E,B,0.82,-0.05,13.165,13.165,63.64,BPA,-1.76767,0.168804,0.00628861,0.807157 beta-lactamase_2500_A170M,beta-lactamase_2500_170,TEM-1,beta-lactamase_2500,P62593,0.807204,NO,170,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.237,-4.595,3.358,,0.126,,L,0.46,-0.35,2.427,,64.69,AHH,-1.63267,0.361275,0.00431903,0.807204 beta-lactamase_0_T263Y,beta-lactamase_0_263,TEM-1,beta-lactamase_0,P62593,0.807273,NO,263,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.0500837,0.0110582,0.807273 kka2_1:2_E235C,kka2_1:2_235,Kka2,kka2_1:2,P00552,0.807291,NO,235,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.955,-5.156,3.201,,0.631,H,A,1.04,0.12,26.048,26.048,65.53,OAH,-2.07267,0.295029,0.0102806,0.807291 beta-lactamase_0_P143S,beta-lactamase_0_143,TEM-1,beta-lactamase_0,P62593,0.807298,NO,143,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.967,-3.441,2.474,,0.075,H,A,0.52,-0.37,11.868,11.868,66.78,OOB,-1.354,0.0500837,0.00114551,0.807298 beta-lactamase_0_A40D,beta-lactamase_0_40,TEM-1,beta-lactamase_0,P62593,0.807381,NO,40,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.402,-3.685,2.283,,0.155,S,B,0.46,0.21,0.783,,73.78,OHB,-1.40267,0.0500837,0.00490026,0.807381 kka2_1:4_D62A,kka2_1:4_62,Kka2,kka2_1:4,P00552,0.807395,NO,62,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.591,-2.125,0.534,,0.262,H,A,0.29,0.08,14.756,14.756,64.39,PAA,-1.77833,0.168804,0.00744243,0.807395 beta-lactamase_G52M,beta-lactamase_52,TEM-1,beta-lactamase,P62593,0.807427,NO,52,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.149,-4.888,3.739,5.12093,0.299,,l,0.77,-0.04,2.103,,64.69,POB,-1.66267,0.221079,0.00340138,0.807427 beta-lactamase_0_E35A,beta-lactamase_0_35,TEM-1,beta-lactamase_0,P62593,0.807453,NO,35,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-0.869,-3.127,2.258,,0.15,H,A,1.04,0.21,0.664,,46.85,HAA,-1.88667,0.0500837,0.00174441,0.807453 Pab1_G193I,Pab1_193,Pab1,Pab1,P04147,0.80754,NO,193,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.414,-4.044,2.63,,,,,,,,,,POP,-1.55733,0.175299,0.0014922,0.80754 kka2_1:4_L241C,kka2_1:4_241,Kka2,kka2_1:4,P00552,0.807543,NO,241,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.158,-3.073,1.915,,0.08,H,A,0.55,-0.82,1.598,,63.26,HHH,-1.58533,0.168804,0.0117299,0.807543 kka2_1:8_G151V,kka2_1:8_151,Kka2,kka2_1:8,P00552,0.807583,NO,151,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.873,-3.846,2.973,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.100394,0.00339918,0.807583 kka2_1:8_G151V,kka2_1:8_151,Kka2,kka2_1:8,P00552,0.807583,NO,151,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.873,-3.846,2.973,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.100394,0.00339918,0.807583 beta-lactamase_0_D177P,beta-lactamase_0_177,TEM-1,beta-lactamase_0,P62593,0.807623,NO,177,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.967,-3.764,2.797,,0.006,T,L,0.75,-1.02,3.536,,64.69,BAP,-0.873667,0.0500837,0.000864022,0.807623 beta-lactamase_0_D231E,beta-lactamase_0_231,TEM-1,beta-lactamase_0,P62593,0.807624,NO,231,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.816,-2.232,1.416,,,E,B,0.75,-1.06,4.975,,65.38,HAB,-0.994,0.0500837,0.00107395,0.807624 Pab1_N132V,Pab1_132,Pab1,Pab1,P04147,0.807643,NO,132,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-1.079,-3.571,2.492,,0.412,S,l,,0.9,,,,BPH,-1.067,0.175299,0.000347671,0.807643 PSD95pdz3_A376C,PSD95pdz3_376,PSD95pdz3,PSD95pdz3,P31016,0.807666,NO,376,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.307,-4.094,2.787,4.72134,,,,,17.108,,,,HHH,-1.49567,0.0758425,0.000341232,0.807666 kka2_1:2_L19T,kka2_1:2_19,Kka2,kka2_1:2,P00552,0.807677,NO,19,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.254,-3.645,2.391,,0.08,T,A,0.55,-0.26,17.165,17.165,65.53,BHH,-2.221,0.295029,0.00620703,0.807677 beta-lactamase_2500_A211V,beta-lactamase_2500_211,TEM-1,beta-lactamase_2500,P62593,0.807708,NO,211,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.896,-3.651,1.755,,0.369,T,A,0.46,-0.69,2.061,,77.62,AHA,-1.94633,0.361275,0.00648183,0.807708 beta-lactamase_0_N98M,beta-lactamase_0_98,TEM-1,beta-lactamase_0,P62593,0.807725,NO,98,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-2.973,-4.74,1.767,,0.963,G,A,0.61,1.35,14.853,14.853,77.62,PPA,-2.07867,0.0500837,0.00505389,0.807725 beta-lactamase_0_A235Q,beta-lactamase_0_235,TEM-1,beta-lactamase_0,P62593,0.807727,NO,235,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.266,-4.018,2.752,,0.32,E,B,0.46,-0.86,2.261,,50,OHO,-0.89,0.0500837,0.00493474,0.807727 kka2_1:4_I254Y,kka2_1:4_254,Kka2,kka2_1:4,P00552,0.807731,NO,254,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.933,-3.144,1.211,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.168804,0.0132375,0.807731 kka2_1:2_Q100S,kka2_1:2_100,Kka2,kka2_1:2,P00552,0.807807,NO,100,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.77,-2.33,-0.44,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.295029,0.0066405,0.807807 Pab1_G126C,Pab1_126,Pab1,Pab1,P04147,0.807811,NO,126,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.985,-4.746,3.761,,0.011,T,A,0.46,-0.07,2.349,,80.42,OOP,-1.032,0.175299,0.00109814,0.807811 beta-lactamase_0_E169F,beta-lactamase_0_169,TEM-1,beta-lactamase_0,P62593,0.807847,NO,169,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.23,-4.322,3.092,,0.337,,A,1.04,1,3.516,,73.08,PAH,-1.16533,0.0500837,0.00400994,0.807847 gb1_T242W,gb1_242,gb1,gb1,P06654,0.807868,NO,242,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.245,-4.833,3.588,,,,,,,,,,APP,-1.444,0.177985,0.00243886,0.807868 gb1_Y259R,gb1_259,gb1,gb1,P06654,0.807868,NO,259,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-1.78,-3.933,2.153,,,,,,,0.131,,11.83,PHH,-1.787,0.177985,0.00464313,0.807868 beta-lactamase_0_R92F,beta-lactamase_0_92,TEM-1,beta-lactamase_0,P62593,0.808002,NO,92,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.718,-4.33,2.612,,0.479,E,B,1.2,1.36,2.331,,65.38,BBH,-1.50367,0.0500837,0.00429626,0.808002 kka2_1:8_F48L,kka2_1:8_48,Kka2,kka2_1:8,P00552,0.808114,NO,48,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.453,-2.543,1.09,,0.296,E,B,1.62,-0.99,14.194,14.194,55.3,HHH,-1.444,0.100394,0.00475422,0.808114 kka2_1:8_F48L,kka2_1:8_48,Kka2,kka2_1:8,P00552,0.808114,NO,48,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.453,-2.543,1.09,,0.296,E,B,1.62,-0.99,14.194,14.194,55.3,HHH,-1.444,0.100394,0.00475422,0.808114 beta-lactamase_39_D212Q,beta-lactamase_39_212,TEM-1,beta-lactamase_39,P62593,0.808138,NO,212,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.624,-3.949,2.325,,0.037,,b,0.75,-0.58,10.748,10.748,74.48,HAB,-1.77667,0.0495842,0.00644302,0.808138 beta-lactamase_V82M,beta-lactamase_82,TEM-1,beta-lactamase,P62593,0.808169,NO,82,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.325,-4.274,2.949,5.27777,0.267,H,A,0.96,0.08,1.379,,93.01,BHA,-1.28567,0.221079,0.00397046,0.808169 kka2_1:8_I196S,kka2_1:8_196,Kka2,kka2_1:8,P00552,0.808202,NO,196,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-2.115,-3.786,1.671,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.100394,0.0107273,0.808202 kka2_1:8_I196S,kka2_1:8_196,Kka2,kka2_1:8,P00552,0.808202,NO,196,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-2.115,-3.786,1.671,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.100394,0.0107273,0.808202 beta-lactamase_39_L137D,beta-lactamase_39_137,TEM-1,beta-lactamase_39,P62593,0.808234,NO,137,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.03,-4.128,3.098,,,H,A,0.55,-0.38,0.674,,42.31,HHP,-1.58933,0.0495842,0.00278599,0.808234 beta-lactamase_E119M,beta-lactamase_119,TEM-1,beta-lactamase,P62593,0.808325,NO,119,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.412,-4.79,3.378,5.33349,0.358,H,A,1.52,0.51,1.983,,63.99,BAH,-1.623,0.221079,0.00386966,0.808325 beta-lactamase_R91M,beta-lactamase_91,TEM-1,beta-lactamase,P62593,0.808325,NO,91,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.392,-4.593,3.201,5.92536,0.444,,B,0.68,0.96,1.318,,50.35,OBB,-1.73367,0.221079,0.00380226,0.808325 beta-lactamase_0_E46R,beta-lactamase_0_46,TEM-1,beta-lactamase_0,P62593,0.808355,NO,46,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.94,-4.04,2.1,,0.021,E,B,1.04,0.14,30.306,30.306,59.44,HAH,-2.079,0.0500837,0.00427568,0.808355 kka2_1:1_G234I,kka2_1:1_234,Kka2,kka2_1:1,P00552,0.808396,NO,234,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-2.9,-4.067,1.167,,0.494,H,A,0.29,-0.29,1.753,,71.59,OOA,-1.86767,0.520039,0.00984449,0.808396 beta-lactamase_2500_S256Y,beta-lactamase_2500_256,TEM-1,beta-lactamase_2500,P62593,0.808436,NO,256,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.361275,0.00710634,0.808436 beta-lactamase_0_G216W,beta-lactamase_0_216,TEM-1,beta-lactamase_0,P62593,0.80852,NO,216,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.477,-5.45,3.973,,0.437,I,A,0.29,-0.58,0.834,,74.48,HOO,-1.68067,0.0500837,0.00639568,0.80852 kka2_1:8_G245C,kka2_1:8_245,Kka2,kka2_1:8,P00552,0.808526,NO,245,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.812,-5.118,4.306,,0.655,T,g,0.75,0.03,1.148,,65.53,HOH,-1.19833,0.100394,0.00683899,0.808526 kka2_1:8_G245C,kka2_1:8_245,Kka2,kka2_1:8,P00552,0.808526,NO,245,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.812,-5.118,4.306,,0.655,T,g,0.75,0.03,1.148,,65.53,HOH,-1.19833,0.100394,0.00683899,0.808526 beta-lactamase_L205V,beta-lactamase_205,TEM-1,beta-lactamase,P62593,0.80857,NO,205,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.922,-2.938,2.016,5.67023,,H,A,1.3,-0.46,0.678,,42.31,PHH,-1.57767,0.221079,0.00255802,0.80857 beta-lactamase_S104T,beta-lactamase_104,TEM-1,beta-lactamase,P62593,0.80858,NO,104,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.015,-3.098,2.083,4.92365,0.04,,b,0.82,0.57,4.02,,63.29,HPO,-1.05267,0.221079,0.00218083,0.80858 beta-lactamase_156_M209Q,beta-lactamase_156_209,TEM-1,beta-lactamase_156,P62593,0.808585,NO,209,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.442,-3.974,2.532,,,H,A,0.55,-0.97,1.066,,64.69,HHA,-1.52633,0.111618,0.00625021,0.808585 kka2_1:1_I2Y,kka2_1:1_2,Kka2,kka2_1:1,P00552,0.808593,NO,2,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.787,-3.837,2.05,,,,,,,2.329,,71.59,HHA,-1.92433,0.520039,0.00246644,0.808593 beta-lactamase_F6T,beta-lactamase_6,TEM-1,beta-lactamase,P62593,0.808601,NO,6,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.847,-3.396,1.549,,,,,,,1.276,,67.83,BHB,-2.076,0.221079,0.00261627,0.808601 kka2_1:1_W24R,kka2_1:1_24,Kka2,kka2_1:1,P00552,0.808648,NO,24,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-1.779,-4.308,2.529,,0.477,E,B,0.47,-0.21,2.375,,56.06,AHH,-2.24467,0.520039,0.00631564,0.808648 beta-lactamase_0_G142H,beta-lactamase_0_142,TEM-1,beta-lactamase_0,P62593,0.808687,NO,142,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.707,-4.678,3.971,,0.034,,p,0.29,-0.64,1.947,,64.69,OOO,-0.834,0.0500837,0.00060149,0.808687 beta-lactamase_39_G234F,beta-lactamase_39_234,TEM-1,beta-lactamase_39,P62593,0.808718,NO,234,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.62,-4.292,3.672,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.0495842,0.000889577,0.808718 beta-lactamase_V82N,beta-lactamase_82,TEM-1,beta-lactamase,P62593,0.808804,NO,82,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.325,-2.935,1.61,5.27777,0.267,H,A,0.96,0.08,1.379,,93.01,BHA,-1.28567,0.221079,0.00397046,0.808804 kka2_1:2_G55A,kka2_1:2_55,Kka2,kka2_1:2,P00552,0.808824,NO,55,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.625,-2.457,0.832,,0.517,S,b,0.75,1.19,15.753,15.753,63.64,POH,-2.05967,0.295029,0.00667877,0.808824 beta-lactamase_0_K53C,beta-lactamase_0_53,TEM-1,beta-lactamase_0,P62593,0.808834,NO,53,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-2.313,-5.135,2.822,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.0500837,0.00383383,0.808834 beta-lactamase_0_K71P,beta-lactamase_0_71,TEM-1,beta-lactamase_0,P62593,0.808839,NO,71,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-0.8,-3.655,2.855,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.0500837,0.00103192,0.808839 kka2_1:4_H135C,kka2_1:4_135,Kka2,kka2_1:4,P00552,0.808874,NO,135,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-1.331,-5.106,3.775,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.168804,0.00532566,0.808874 Pab1_K164P,Pab1_164,Pab1,Pab1,P04147,0.808922,NO,164,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-2.298,-3.87,1.572,,,,,,,,,,OBP,-1.41767,0.175299,0.00255241,0.808922 beta-lactamase_0_L47W,beta-lactamase_0_47,TEM-1,beta-lactamase_0,P62593,0.808925,NO,47,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.876,-5.24,3.364,,0.007,E,B,0.55,0.2,1.024,,67.83,AHA,-1.639,0.0500837,0.00439844,0.808925 gb1_Y229V,gb1_229,gb1,gb1,P06654,0.808927,NO,229,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-1.282,-3.039,1.757,,,,,,,,,,PHB,-1.4915,0.177985,0.00366605,0.808927 Pab1_L133T,Pab1_133,Pab1,Pab1,P04147,0.809041,NO,133,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.039,-3.239,2.2,,0.015,,B,1.75,1.03,,,,PHB,-1.22,0.175299,0.000345939,0.809041 beta-lactamase_V214C,beta-lactamase_214,TEM-1,beta-lactamase,P62593,0.80906,NO,214,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.299,-4.725,3.426,5.74008,0.375,S,A,1.19,-0.44,1.899,,74.48,BHH,-1.53733,0.221079,0.00628442,0.80906 kka2_1:4_Y257H,kka2_1:4_257,Kka2,kka2_1:4,P00552,0.809063,NO,257,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-1.064,-4.042,2.978,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.168804,0.0148191,0.809063 beta-lactamase_A15N,beta-lactamase_15,TEM-1,beta-lactamase,P62593,0.809123,NO,15,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.654,-3.676,2.022,,,,,,,31.998,31.998,93.01,HHH,-2.10833,0.221079,0.00248966,0.809123 beta-lactamase_0_G226N,beta-lactamase_0_226,TEM-1,beta-lactamase_0,P62593,0.809177,NO,226,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.461,-2.628,1.167,,0.701,T,l,0.29,-0.25,23.034,23.034,74.48,HOH,-1.42933,0.0500837,0.00665294,0.809177 beta-lactamase_2500_M270H,beta-lactamase_2500_270,TEM-1,beta-lactamase_2500,P62593,0.809224,NO,270,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.723,,,,0.422,H,A,1.59,1.15,2.029,,64.34,PHA,-1.70933,0.361275,0.00767762,0.809224 kka2_1:1_D101S,kka2_1:1_101,Kka2,kka2_1:1,P00552,0.809231,NO,101,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.028,-3.266,2.238,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.520039,0.00423361,0.809231 beta-lactamase_0_L248H,beta-lactamase_0_248,TEM-1,beta-lactamase_0,P62593,0.809236,NO,248,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.0500837,0.00428493,0.809236 beta-lactamase_0_S51H,beta-lactamase_0_51,TEM-1,beta-lactamase_0,P62593,0.809295,NO,51,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.526,-4.622,3.096,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.0500837,0.00504821,0.809295 beta-lactamase_P143G,beta-lactamase_143,TEM-1,beta-lactamase,P62593,0.809301,NO,143,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.967,-3.499,2.532,5.16366,0.075,H,A,0.99,-0.37,0.479,,66.78,OOB,-1.354,0.221079,0.00114551,0.809301 kka2_1:2_L93I,kka2_1:2_93,Kka2,kka2_1:2,P00552,0.809312,NO,93,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.815,-3.008,2.193,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.295029,0.00131498,0.809312 beta-lactamase_L282Q,beta-lactamase_282,TEM-1,beta-lactamase,P62593,0.809328,NO,282,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.586,-4.192,2.606,5.16743,0.007,H,A,1.07,0.34,31.31,31.31,63.99,PHH,-1.82367,0.221079,0.0449821,0.809328 beta-lactamase_E195W,beta-lactamase_195,TEM-1,beta-lactamase,P62593,0.80937,NO,195,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.186,-5.555,3.369,7.28489,1.016,S,A,1.52,0.85,2.583,,77.62,OAH,-2.02,0.221079,0.00496565,0.80937 beta-lactamase_0_L47P,beta-lactamase_0_47,TEM-1,beta-lactamase_0,P62593,0.809385,NO,47,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.876,-4.153,2.277,,0.007,E,B,0.55,0.2,1.024,,67.83,AHA,-1.639,0.0500837,0.00439844,0.809385 PSD95pdz3_A375I,PSD95pdz3_375,PSD95pdz3,PSD95pdz3,P31016,0.809436,NO,375,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.307,-3.242,1.935,5.05512,,,,,13.888,,,,PHH,-1.43767,0.0758425,0.000356809,0.809436 gb1_A246P,gb1_246,gb1,gb1,P06654,0.809454,NO,246,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.175,-3.39,2.215,,,,,,,,,,AHH,-1.87033,0.177985,0.00190625,0.809454 gb1_E282A,gb1_282,gb1,gb1,P06654,0.809454,NO,282,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.318,-2.767,1.449,,,,,,,1.075,,35.71,PAO,-1.573,0.177985,0.00209643,0.809454 gb1_G235T,gb1_235,gb1,gb1,P06654,0.809454,NO,235,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.419,-1.684,0.265,,,,,,,0.476,,11.83,POB,-1.86433,0.177985,0.00297491,0.809454 gb1_N263L,gb1_263,gb1,gb1,P06654,0.809454,NO,263,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-1.162,-3.36,2.198,,,,,,,,,,APO,-2.04233,0.177985,0.0035297,0.809454 beta-lactamase_0_R59S,beta-lactamase_0_59,TEM-1,beta-lactamase_0,P62593,0.809523,NO,59,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.345,-2.706,1.361,,0.329,S,L,1.2,-0.09,2.919,,73.08,HBO,-2.24267,0.0500837,0.00318082,0.809523 beta-lactamase_0_F70C,beta-lactamase_0_70,TEM-1,beta-lactamase_0,P62593,0.809525,NO,70,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.169,-4.871,3.702,,,H,A,0.58,-1.34,2.153,,63.99,PHB,-0.980667,0.0500837,0.00193499,0.809525 beta-lactamase_R91Y,beta-lactamase_91,TEM-1,beta-lactamase,P62593,0.809541,NO,91,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.392,-4.246,2.854,5.92536,0.444,,B,0.68,0.96,1.318,,50.35,OBB,-1.73367,0.221079,0.00380226,0.809541 beta-lactamase_0_G43L,beta-lactamase_0_43,TEM-1,beta-lactamase_0,P62593,0.809606,NO,43,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.62,-3.808,3.188,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.0500837,0.00120151,0.809606 kka2_1:1_E3Y,kka2_1:1_3,Kka2,kka2_1:1,P00552,0.80964,NO,3,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.199,-2.458,0.259,,,,,,,3.435,,92.05,HAP,-2.11567,0.520039,0.00267607,0.80964 beta-lactamase_2500_I140Y,beta-lactamase_2500_140,TEM-1,beta-lactamase_2500,P62593,0.809674,NO,140,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.733,-3.996,2.263,,0.128,H,A,0.48,0.41,1.628,,73.08,PHO,-1.48733,0.361275,0.00597777,0.809674 Pab1_A141R,Pab1_141,Pab1,Pab1,P04147,0.809725,NO,141,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.461,-3.636,2.175,,0.34,H,A,0.52,-0.27,2.15,,79.03,BHH,-1.19433,0.175299,0.00165974,0.809725 kka2_1:8_R211L,kka2_1:8_211,Kka2,kka2_1:8,P00552,0.809819,NO,211,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-0.899,-3.41,2.511,,0.12,T,a,0.16,-0.39,0.615,,49.62,OBH,-0.966,0.100394,0.00204888,0.809819 kka2_1:8_R211L,kka2_1:8_211,Kka2,kka2_1:8,P00552,0.809819,NO,211,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-0.899,-3.41,2.511,,0.12,T,a,0.16,-0.39,0.615,,49.62,OBH,-0.966,0.100394,0.00204888,0.809819 beta-lactamase_T261H,beta-lactamase_261,TEM-1,beta-lactamase,P62593,0.809838,NO,261,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.88,-4.918,2.038,5.65483,0.014,E,B,0.53,-0.39,2.449,,77.62,HPP,-1.771,0.221079,0.0123091,0.809838 beta-lactamase_T131L,beta-lactamase_131,TEM-1,beta-lactamase,P62593,0.809917,NO,131,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.328,-3.319,1.991,5.0548,,H,A,0.53,-0.69,3.306,,67.48,PPH,-1.00867,0.221079,0.00345886,0.809917 gb1_Y259C,gb1_259,gb1,gb1,P06654,0.809979,NO,259,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-1.78,-4.728,2.948,,,,,,,0.131,,11.83,PHH,-1.787,0.177985,0.00464313,0.809979 beta-lactamase_0_L160D,beta-lactamase_0_160,TEM-1,beta-lactamase_0,P62593,0.810022,NO,160,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.977,-4.122,3.145,,0.022,,B,0.55,-0.6,0.68,,44.41,BHA,-0.936,0.0500837,0.00193775,0.810022 beta-lactamase_156_S241Y,beta-lactamase_156_241,TEM-1,beta-lactamase_156,P62593,0.810058,NO,241,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.111618,0.00452736,0.810058 kka2_1:2_A110G,kka2_1:2_110,Kka2,kka2_1:2,P00552,0.810106,NO,110,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.064,-2.863,0.799,,0.175,H,A,0.46,-1.19,23.237,23.237,71.59,OHA,-1.91867,0.295029,0.00759851,0.810106 beta-lactamase_K232R,beta-lactamase_232,TEM-1,beta-lactamase,P62593,0.810155,NO,232,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.012,-1.888,0.876,5.18286,,E,B,2.92,-1.1,1.174,,65.03,ABP,-1.238,0.221079,0.00313441,0.810155 WW_domain_P172F,WW_domain_172,Yap65,WW_domain,P46937,0.810155,NO,172,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.035,-4.294,3.259,,,,,,,,,,HOH,-1.233,0.153962,0.000991485,0.810155 kka2_1:1_S68T,kka2_1:1_68,Kka2,kka2_1:1,P00552,0.810247,NO,68,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.623,-3.655,1.032,,0.48,H,A,0.27,-0.1,2.655,,71.59,HPH,-1.40767,0.520039,0.00608265,0.810247 kka2_1:8_F240R,kka2_1:8_240,Kka2,kka2_1:8,P00552,0.810281,NO,240,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-0.911,-4.185,3.274,,,H,A,1.62,-1.21,0.697,,50.38,BHH,-1.67267,0.100394,0.00552543,0.810281 kka2_1:8_F240R,kka2_1:8_240,Kka2,kka2_1:8,P00552,0.810281,NO,240,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-0.911,-4.185,3.274,,,H,A,1.62,-1.21,0.697,,50.38,BHH,-1.67267,0.100394,0.00552543,0.810281 kka2_1:4_A78R,kka2_1:4_78,Kka2,kka2_1:4,P00552,0.810301,NO,78,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.744,-3.937,2.193,,0.078,.,B,0.46,-0.53,0.594,,56.06,OHH,-1.863,0.168804,0.00457299,0.810301 kka2_1:8_L126A,kka2_1:8_126,Kka2,kka2_1:8,P00552,0.810317,NO,126,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.246,-3.18,1.934,,0.285,S,B,1.59,0.12,4.443,,51.89,PHA,-1.744,0.100394,0.0066485,0.810317 kka2_1:8_L126A,kka2_1:8_126,Kka2,kka2_1:8,P00552,0.810317,NO,126,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.246,-3.18,1.934,,0.285,S,B,1.59,0.12,4.443,,51.89,PHA,-1.744,0.100394,0.0066485,0.810317 beta-lactamase_0_R63A,beta-lactamase_0_63,TEM-1,beta-lactamase_0,P62593,0.810319,NO,63,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-0.943,-3.103,2.16,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.0500837,0.00126938,0.810319 beta-lactamase_0_K32I,beta-lactamase_0_32,TEM-1,beta-lactamase_0,P62593,0.810369,NO,32,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.984,-2.835,0.851,,0.563,H,A,2.34,0.34,0.418,,73.08,HBA,-2.04233,0.0500837,0.00401283,0.810369 beta-lactamase_S201L,beta-lactamase_201,TEM-1,beta-lactamase,P62593,0.810375,NO,201,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.183,-2.615,1.432,4.85496,0.064,H,A,0.77,-0.07,4.045,,64.69,HPB,-1.451,0.221079,0.00198815,0.810375 kka2_1:4_V214G,kka2_1:4_214,Kka2,kka2_1:4,P00552,0.810379,NO,214,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.261,-3.813,2.552,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.168804,0.00692782,0.810379 beta-lactamase_G263L,beta-lactamase_263,TEM-1,beta-lactamase,P62593,0.810481,NO,263,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-2.031,-3.651,1.62,5.09799,0.517,S,l,0.77,0.31,16.425,16.425,77.62,POP,-1.78267,0.221079,0.0110582,0.810481 gb1_T237E,gb1_237,gb1,gb1,P06654,0.810502,NO,237,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.736,-3.265,1.529,,,,,,,0.218,,11.83,BPH,-2.27833,0.177985,0.00275316,0.810502 kka2_1:4_A41W,kka2_1:4_41,Kka2,kka2_1:4,P00552,0.810508,NO,41,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.879,-3.701,1.822,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.168804,0.00543332,0.810508 beta-lactamase_L137C,beta-lactamase_137,TEM-1,beta-lactamase,P62593,0.810513,NO,137,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.03,-4.702,3.672,5.20117,,H,A,1.07,-0.38,0.674,,42.31,HHP,-1.58933,0.221079,0.00278599,0.810513 beta-lactamase_0_R63I,beta-lactamase_0_63,TEM-1,beta-lactamase_0,P62593,0.810534,NO,63,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-0.943,-3.824,2.881,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.0500837,0.00126938,0.810534 kka2_1:8_R258S,kka2_1:8_258,Kka2,kka2_1:8,P00552,0.810551,NO,258,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.626,-3.501,1.875,,0.316,H,A,0.16,-0.85,5.58,,53.03,HBH,-1.25933,0.100394,0.00983174,0.810551 kka2_1:8_R258S,kka2_1:8_258,Kka2,kka2_1:8,P00552,0.810551,NO,258,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.626,-3.501,1.875,,0.316,H,A,0.16,-0.85,5.58,,53.03,HBH,-1.25933,0.100394,0.00983174,0.810551 beta-lactamase_0_G141P,beta-lactamase_0_141,TEM-1,beta-lactamase_0,P62593,0.81057,NO,141,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.828,-3.881,3.053,,0.575,T,l,0.29,-0.28,0.722,,64.69,HOO,-1.08933,0.0500837,0.0012419,0.81057 beta-lactamase_2500_S122C,beta-lactamase_2500_122,TEM-1,beta-lactamase_2500,P62593,0.810578,NO,122,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.406,-5.091,2.685,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.361275,0.00497825,0.810578 WW_domain_G176H,WW_domain_176,Yap65,WW_domain,P46937,0.810583,NO,176,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.235,-4.449,3.214,6.33142,,,,,,2.71,,78.57,HOH,-1.35467,0.153962,0.00288552,0.810583 beta-lactamase_625_G114K,beta-lactamase_625_114,TEM-1,beta-lactamase_625,P62593,0.810591,NO,114,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.094,-3.566,2.472,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.213352,0.00224919,0.810591 kka2_1:2_D220A,kka2_1:2_220,Kka2,kka2_1:2,P00552,0.810638,NO,220,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.787,-3.298,2.511,,,H,A,0.75,-1.14,0.745,,46.59,PAH,-1.152,0.295029,0.00158066,0.810638 kka2_1:8_H188L,kka2_1:8_188,Kka2,kka2_1:8,P00552,0.810727,NO,188,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-0.913,-3.61,2.697,,0.006,,A,0.87,-1.02,1.241,,47.73,PBO,-0.927333,0.100394,0.00273139,0.810727 kka2_1:8_H188L,kka2_1:8_188,Kka2,kka2_1:8,P00552,0.810727,NO,188,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-0.913,-3.61,2.697,,0.006,,A,0.87,-1.02,1.241,,47.73,PBO,-0.927333,0.100394,0.00273139,0.810727 kka2_1:4_F240C,kka2_1:4_240,Kka2,kka2_1:4,P00552,0.810762,NO,240,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-0.911,-4.889,3.978,,,H,A,0.58,-1.21,5.798,,50.38,BHH,-1.67267,0.168804,0.00552543,0.810762 Pab1_S165I,Pab1_165,Pab1,Pab1,P04147,0.810822,NO,165,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.146,-3.602,2.456,,0.12,,a,,0.11,,,,BPB,-1.56867,0.175299,0.000307838,0.810822 kka2_1:4_T28G,kka2_1:4_28,Kka2,kka2_1:4,P00552,0.810838,NO,28,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.883,-2.414,0.531,,0.353,S,B,0.82,2.02,4.415,,63.64,PPH,-1.74467,0.168804,0.00743084,0.810838 kka2_1:8_G201L,kka2_1:8_201,Kka2,kka2_1:8,P00552,0.810844,NO,201,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.56,-3.824,2.264,,0.149,T,l,0.75,-0.57,2.152,,52.65,POB,-1.92233,0.100394,0.00820117,0.810844 kka2_1:8_G201L,kka2_1:8_201,Kka2,kka2_1:8,P00552,0.810844,NO,201,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.56,-3.824,2.264,,0.149,T,l,0.75,-0.57,2.152,,52.65,POB,-1.92233,0.100394,0.00820117,0.810844 kka2_1:2_G201R,kka2_1:2_201,Kka2,kka2_1:2,P00552,0.810901,NO,201,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.56,-2.756,1.196,,0.149,T,l,0.29,-0.57,16.092,16.092,52.65,POB,-1.92233,0.295029,0.00820117,0.810901 beta-lactamase_V21K,beta-lactamase_21,TEM-1,beta-lactamase,P62593,0.810933,NO,21,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.873,-3.409,1.536,,,,,,,0.688,,93.01,OHH,-2.09633,0.221079,0.0028612,0.810933 kka2_1:4_R140G,kka2_1:4_140,Kka2,kka2_1:4,P00552,0.810937,NO,140,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.351,-2.695,1.344,,0.12,H,A,1.2,0.2,2.561,,53.03,BBH,-1.885,0.168804,0.00430167,0.810937 PSD95pdz3_L353Q,PSD95pdz3_353,PSD95pdz3,PSD95pdz3,P31016,0.810956,NO,353,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.347,-3.806,2.459,5.81136,,,,,17.3525,,,,AHB,-1.50533,0.0758425,0.000664742,0.810956 kka2_1:1_S251T,kka2_1:1_251,Kka2,kka2_1:1,P00552,0.810968,NO,251,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.636,-3.052,0.416,,0.712,H,A,0.27,-0.25,1.356,,71.59,APP,-2.09367,0.520039,0.0138916,0.810968 beta-lactamase_2500_S57L,beta-lactamase_2500_57,TEM-1,beta-lactamase_2500,P62593,0.810981,NO,57,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.918,-2.848,0.93,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.361275,0.00492804,0.810981 beta-lactamase_0_N274K,beta-lactamase_0_274,TEM-1,beta-lactamase_0,P62593,0.811049,NO,274,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.0500837,0.0110418,0.811049 beta-lactamase_2500_E46I,beta-lactamase_2500_46,TEM-1,beta-lactamase_2500,P62593,0.8111,NO,46,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.94,-2.064,0.124,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.361275,0.00427568,0.8111 WW_domain_T182V,WW_domain_182,Yap65,WW_domain,P46937,0.811147,NO,182,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.149,-2.856,1.707,6.20597,,,,,,,,,BPP,-1.483,0.153962,0.00294574,0.811147 beta-lactamase_M66Q,beta-lactamase_66,TEM-1,beta-lactamase,P62593,0.811156,NO,66,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.362,-3.949,2.587,5.29561,0.013,,A,1.3,-0.7,1.319,,73.08,OHH,-1.49567,0.221079,0.00412876,0.811156 kka2_1:4_D157F,kka2_1:4_157,Kka2,kka2_1:4,P00552,0.811157,NO,157,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.993,-4.394,3.401,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.168804,0.0042313,0.811157 PSD95pdz3_I341K,PSD95pdz3_341,PSD95pdz3,PSD95pdz3,P31016,0.811162,NO,341,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.63,-3.589,1.959,5.73946,,,,,10.3187,,,,HHH,-1.50033,0.0758425,0.000824087,0.811162 kka2_1:1_L47P,kka2_1:1_47,Kka2,kka2_1:1,P00552,0.811195,NO,47,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.265,-4.146,2.881,,0.139,E,B,0.55,-0.86,14.593,14.593,63.26,HHH,-1.77933,0.520039,0.00509386,0.811195 PSD95pdz3_A378P,PSD95pdz3_378,PSD95pdz3,PSD95pdz3,P31016,0.811212,NO,378,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.307,-3.336,2.029,4.86582,,,,,14.576,,,,HHH,-1.509,0.0758425,0.000313169,0.811212 beta-lactamase_0_L28E,beta-lactamase_0_28,TEM-1,beta-lactamase_0,P62593,0.811221,NO,28,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.579,-3.677,2.098,,0.277,H,A,0.55,-0.16,9.35,9.35,93.01,PHH,-2.11333,0.0500837,0.00359321,0.811221 PSD95pdz3_I388S,PSD95pdz3_388,PSD95pdz3,PSD95pdz3,P31016,0.811231,NO,388,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.63,-3.292,1.662,5.17282,,,,,16.0025,,,,PHH,-1.54967,0.0758425,0.000151216,0.811231 kka2_1:1_Q27R,kka2_1:1_27,Kka2,kka2_1:1,P00552,0.811255,NO,27,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-1.659,-3.828,2.169,,0.608,.,A,0.64,0.71,0.521,,65.53,PPP,-1.90733,0.520039,0.00595365,0.811255 beta-lactamase_L120C,beta-lactamase_120,TEM-1,beta-lactamase,P62593,0.811261,NO,120,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.044,-4.81,3.766,5.11974,,H,A,1.3,-1.13,1.988,,64.69,AHO,-1.13633,0.221079,0.00143563,0.811261 beta-lactamase_0_A40Q,beta-lactamase_0_40,TEM-1,beta-lactamase_0,P62593,0.811319,NO,40,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.402,-4.1,2.698,,0.155,S,B,0.46,0.21,0.783,,73.78,OHB,-1.40267,0.0500837,0.00490026,0.811319 kka2_1:8_G99N,kka2_1:8_99,Kka2,kka2_1:8,P00552,0.81134,NO,99,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.596,-3.476,2.88,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.100394,0.00186055,0.81134 kka2_1:8_G99N,kka2_1:8_99,Kka2,kka2_1:8,P00552,0.81134,NO,99,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.596,-3.476,2.88,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.100394,0.00186055,0.81134 Pab1_G169S,Pab1_169,Pab1,Pab1,P04147,0.811349,NO,169,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.809,-2.978,2.169,,,E,b,0.35,0.03,,,,HOH,-1.11567,0.175299,0.000302434,0.811349 beta-lactamase_2500_G216K,beta-lactamase_2500_216,TEM-1,beta-lactamase_2500,P62593,0.811371,NO,216,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.477,-2.765,1.288,,0.437,I,A,0.29,-0.58,1.983,,74.48,HOO,-1.68067,0.361275,0.00639568,0.811371 kka2_1:4_E17M,kka2_1:4_17,Kka2,kka2_1:4,P00552,0.811382,NO,17,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.154,-4.855,2.701,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.168804,0.00688738,0.811382 beta-lactamase_0_S256T,beta-lactamase_0_256,TEM-1,beta-lactamase_0,P62593,0.811404,NO,256,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.0500837,0.00710634,0.811404 beta-lactamase_R202N,beta-lactamase_202,TEM-1,beta-lactamase,P62593,0.81142,NO,202,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.292,-3.543,2.251,5.16273,0.188,H,A,0.68,0.62,1.918,,77.62,PBP,-1.54767,0.221079,0.00321899,0.81142 beta-lactamase_0_A170V,beta-lactamase_0_170,TEM-1,beta-lactamase_0,P62593,0.811485,NO,170,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.237,-2.64,1.403,,0.126,,L,0.46,-0.35,2.427,,64.69,AHH,-1.63267,0.0500837,0.00431903,0.811485 kka2_1:2_R173G,kka2_1:2_173,Kka2,kka2_1:2,P00552,0.811521,NO,173,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.407,-3.552,1.145,,0.308,H,A,0.16,-0.13,15.389,15.389,65.53,HBH,-1.70533,0.295029,0.00784999,0.811521 kka2_1:4_R89N,kka2_1:4_89,Kka2,kka2_1:4,P00552,0.811614,NO,89,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.548,-3.002,1.454,,0.209,E,B,1.2,1.41,4.412,,64.39,OBA,-1.89867,0.168804,0.00524373,0.811614 kka2_1:8_L241D,kka2_1:8_241,Kka2,kka2_1:8,P00552,0.811632,NO,241,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.158,-4.14,2.982,,0.08,H,A,1.59,-0.82,1.136,,63.26,HHH,-1.58533,0.100394,0.0117299,0.811632 kka2_1:8_L241D,kka2_1:8_241,Kka2,kka2_1:8,P00552,0.811632,NO,241,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.158,-4.14,2.982,,0.08,H,A,1.59,-0.82,1.136,,63.26,HHH,-1.58533,0.100394,0.0117299,0.811632 kka2_1:8_V198G,kka2_1:8_198,Kka2,kka2_1:8,P00552,0.811632,NO,198,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.719,-3.368,1.649,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.100394,0.00835002,0.811632 kka2_1:8_V198G,kka2_1:8_198,Kka2,kka2_1:8,P00552,0.811632,NO,198,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.719,-3.368,1.649,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.100394,0.00835002,0.811632 kka2_1:4_G164V,kka2_1:4_164,Kka2,kka2_1:4,P00552,0.811635,NO,164,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.869,-3.836,2.967,,0.862,T,l,0.75,1.45,1.539,,64.39,POH,-1.828,0.168804,0.00442091,0.811635 beta-lactamase_0_L137S,beta-lactamase_0_137,TEM-1,beta-lactamase_0,P62593,0.81164,NO,137,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.03,-3.64,2.61,,,H,A,0.55,-0.38,0.328,,42.31,HHP,-1.58933,0.0500837,0.00278599,0.81164 beta-lactamase_0_R273H,beta-lactamase_0_273,TEM-1,beta-lactamase_0,P62593,0.811655,NO,273,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.314,-4.599,2.285,,0.564,H,A,1.2,1.57,20.248,20.248,73.78,ABP,-1.841,0.0500837,0.0077952,0.811655 beta-lactamase_2500_Q203F,beta-lactamase_2500_203,TEM-1,beta-lactamase_2500,P62593,0.811698,NO,203,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.168,-4.379,2.211,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.361275,0.00631514,0.811698 beta-lactamase_0_M209I,beta-lactamase_0_209,TEM-1,beta-lactamase_0,P62593,0.811712,NO,209,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.442,-3.121,1.679,,,H,A,0.55,-0.97,3.876,,64.69,HHA,-1.52633,0.0500837,0.00625021,0.811712 kka2_1:8_L259Q,kka2_1:8_259,Kka2,kka2_1:8,P00552,0.811719,NO,259,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.088,-4.124,3.036,,0.036,H,A,1.59,-0.15,1.83,,48.48,BHH,-1.15167,0.100394,0.0206964,0.811719 kka2_1:8_L259Q,kka2_1:8_259,Kka2,kka2_1:8,P00552,0.811719,NO,259,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.088,-4.124,3.036,,0.036,H,A,1.59,-0.15,1.83,,48.48,BHH,-1.15167,0.100394,0.0206964,0.811719 beta-lactamase_P224H,beta-lactamase_224,TEM-1,beta-lactamase,P62593,0.811895,NO,224,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.893,-4.649,3.756,5.179,0.383,,B,0.99,-0.3,0.383,,74.48,HOH,-1.26433,0.221079,0.00189564,0.811895 WW_domain_K181D,WW_domain_181,Yap65,WW_domain,P46937,0.811912,NO,181,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.35,-3.418,2.068,5.0864,,,,,,0.176,,15.87,HBP,-1.247,0.153962,0.0033022,0.811912 beta-lactamase_L197K,beta-lactamase_197,TEM-1,beta-lactamase,P62593,0.811993,NO,197,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.853,-3.679,2.826,5.19172,0.007,S,B,1.3,0.33,1.756,,60.14,HHP,-1.833,0.221079,0.00144602,0.811993 kka2_1:4_L57K,kka2_1:4_57,Kka2,kka2_1:4,P00552,0.812057,NO,57,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.898,-3.894,1.996,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.168804,0.00723769,0.812057 gb1_Y259G,gb1_259,gb1,gb1,P06654,0.812062,NO,259,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-1.78,-3.388,1.608,,,,,,,0.131,,11.83,PHH,-1.787,0.177985,0.00464313,0.812062 beta-lactamase_39_L188E,beta-lactamase_39_188,TEM-1,beta-lactamase_39,P62593,0.812106,NO,188,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.166,-2.834,1.668,,,H,A,0.55,-0.3,2.982,,60.14,PHB,-1.47033,0.0495842,0.00295687,0.812106 beta-lactamase_V78A,beta-lactamase_78,TEM-1,beta-lactamase,P62593,0.812132,NO,78,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.459,-3.121,1.662,4.79197,,H,A,0.96,-0.47,1.132,,63.64,HHH,-1.17833,0.221079,0.00492501,0.812132 kka2_1:2_R18W,kka2_1:2_18,Kka2,kka2_1:2,P00552,0.812186,NO,18,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.055,-5.448,3.393,,0.474,T,A,1.2,0.54,8.405,8.405,71.59,ABH,-1.821,0.295029,0.00724065,0.812186 kka2_1:2_E230R,kka2_1:2_230,Kka2,kka2_1:2,P00552,0.812201,NO,230,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.672,-2.504,-0.168,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.295029,0.00920051,0.812201 beta-lactamase_0_G142P,beta-lactamase_0_142,TEM-1,beta-lactamase_0,P62593,0.812207,NO,142,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.707,-3.877,3.17,,0.034,,p,0.29,-0.64,1.947,,64.69,OOO,-0.834,0.0500837,0.00060149,0.812207 beta-lactamase_0_S241D,beta-lactamase_0_241,TEM-1,beta-lactamase_0,P62593,0.812252,NO,241,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.0500837,0.00452736,0.812252 beta-lactamase_F70I,beta-lactamase_70,TEM-1,beta-lactamase,P62593,0.812265,NO,70,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.169,-3.353,2.184,5.42055,,H,A,1.1,-1.34,1.14,,63.99,PHB,-0.980667,0.221079,0.00193499,0.812265 beta-lactamase_D231A,beta-lactamase_231,TEM-1,beta-lactamase,P62593,0.812277,NO,231,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.816,-3.3,2.484,5.06651,,E,B,1.22,-1.06,0.319,,65.38,HAB,-0.994,0.221079,0.00107395,0.812277 beta-lactamase_0_S96C,beta-lactamase_0_96,TEM-1,beta-lactamase_0,P62593,0.812338,NO,96,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.27,-5.145,2.875,,0.368,,b,0.27,0.39,2.516,,73.78,HPP,-2.019,0.0500837,0.00551835,0.812338 beta-lactamase_0_K71D,beta-lactamase_0_71,TEM-1,beta-lactamase_0,P62593,0.812371,NO,71,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-0.8,-3.469,2.669,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.0500837,0.00103192,0.812371 beta-lactamase_D212T,beta-lactamase_212,TEM-1,beta-lactamase,P62593,0.812386,NO,212,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.624,-2.54,0.916,4.9705,0.037,,b,1.3,-0.58,12.482,,74.48,HAB,-1.77667,0.221079,0.00644302,0.812386 PSD95pdz3_L353H,PSD95pdz3_353,PSD95pdz3,PSD95pdz3,P31016,0.812433,NO,353,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.347,-4.587,3.24,5.81136,,,,,17.3525,,,,AHB,-1.50533,0.0758425,0.000664742,0.812433 kka2_1:8_D250F,kka2_1:8_250,Kka2,kka2_1:8,P00552,0.812447,NO,250,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.015,-4.403,3.388,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.100394,0.0177103,0.812447 kka2_1:8_D250F,kka2_1:8_250,Kka2,kka2_1:8,P00552,0.812447,NO,250,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.015,-4.403,3.388,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.100394,0.0177103,0.812447 beta-lactamase_0_M180Y,beta-lactamase_0_180,TEM-1,beta-lactamase_0,P62593,0.812458,NO,180,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-2.795,-2.93,0.135,,0.242,,B,0.55,-0.94,2.892,,77.62,PHO,-1.56433,0.0500837,0.00552048,0.812458 kka2_1:2_V75E,kka2_1:2_75,Kka2,kka2_1:2,P00552,0.812478,NO,75,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-2.06,-3.835,1.775,,0.042,.,B,0.44,-0.2,2.815,,71.59,OHO,-1.563,0.295029,0.00693733,0.812478 beta-lactamase_0_L135H,beta-lactamase_0_135,TEM-1,beta-lactamase_0,P62593,0.812513,NO,135,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.002,-4.934,3.932,,0.117,H,A,0.55,-0.58,0.705,,43.71,PHH,-1.03767,0.0500837,0.00244423,0.812513 kka2_1:1_A248D,kka2_1:1_248,Kka2,kka2_1:1,P00552,0.812513,NO,248,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.124,-2.58,0.456,,0.825,S,b,0.46,0.46,24.72,24.72,92.05,HHO,-2.15,0.520039,0.0125484,0.812513 kka2_1:2_P98G,kka2_1:2_98,Kka2,kka2_1:2,P00552,0.812542,NO,98,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.526,-3.498,1.972,,0.391,S,B,0.52,-0.65,2.82,,63.26,HOO,-1.19167,0.295029,0.00622754,0.812542 beta-lactamase_0_S241M,beta-lactamase_0_241,TEM-1,beta-lactamase_0,P62593,0.812559,NO,241,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.0500837,0.00452736,0.812559 beta-lactamase_0_H151V,beta-lactamase_0_151,TEM-1,beta-lactamase_0,P62593,0.812576,NO,151,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-2.96,-3.785,0.825,,0.594,H,A,0.17,0.1,9.375,,77.62,HBP,-2.34767,0.0500837,0.00216946,0.812576 gb1_A246Y,gb1_246,gb1,gb1,P06654,0.812578,NO,246,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.175,-3.898,2.723,,,,,,,,,,AHH,-1.87033,0.177985,0.00190625,0.812578 beta-lactamase_2500_F149T,beta-lactamase_2500_149,TEM-1,beta-lactamase_2500,P62593,0.812596,NO,149,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.299,-3.669,2.37,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.361275,0.00418462,0.812596 beta-lactamase_0_L199P,beta-lactamase_0_199,TEM-1,beta-lactamase_0,P62593,0.812608,NO,199,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-2.942,-2.099,-0.843,,0.832,H,A,0.55,0.42,10.85,10.85,77.62,PHH,-2.32933,0.0500837,0.0048649,0.812608 beta-lactamase_0_R220V,beta-lactamase_0_220,TEM-1,beta-lactamase_0,P62593,0.812618,NO,220,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-0.942,-3.675,2.733,,0.295,I,A,1.2,-0.76,21.573,21.573,74.48,HBP,-1.33633,0.0500837,0.00232421,0.812618 beta-lactamase_0_L150R,beta-lactamase_0_150,TEM-1,beta-lactamase_0,P62593,0.812681,NO,150,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.326,-3.982,2.656,,,H,A,0.55,-0.2,2.128,,62.94,HHB,-1.86167,0.0500837,0.00463171,0.812681 beta-lactamase_A170K,beta-lactamase_170,TEM-1,beta-lactamase,P62593,0.812771,NO,170,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.237,-3.643,2.406,5.19261,0.126,,L,2.34,-0.35,2.427,,64.69,AHH,-1.63267,0.221079,0.00431903,0.812771 beta-lactamase_P224S,beta-lactamase_224,TEM-1,beta-lactamase,P62593,0.812795,NO,224,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.893,-2.58,1.687,5.179,0.383,,B,0.99,-0.3,0.383,,74.48,HOH,-1.26433,0.221079,0.00189564,0.812795 beta-lactamase_N168C,beta-lactamase_168,TEM-1,beta-lactamase,P62593,0.812814,NO,168,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-1.029,-4.99,3.961,5.42128,0.113,G,A,0.09,-0.4,1.211,,44.41,HPA,-1.13233,0.221079,0.00288667,0.812814 beta-lactamase_156_L79T,beta-lactamase_156_79,TEM-1,beta-lactamase_156,P62593,0.812815,NO,79,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.842,-3.447,2.605,,0.007,H,A,0.55,-0.16,1.831,,50.35,HHP,-1.44333,0.111618,0.000947397,0.812815 beta-lactamase_0_A185I,beta-lactamase_0_185,TEM-1,beta-lactamase_0,P62593,0.812836,NO,185,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.406,-3.361,1.955,,,H,A,0.46,-1.02,1.203,,65.03,HHP,-1.84033,0.0500837,0.00467449,0.812836 beta-lactamase_V42A,beta-lactamase_42,TEM-1,beta-lactamase,P62593,0.812866,NO,42,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.564,-2.554,0.99,5.27904,0.017,E,B,1.64,-0.51,2.024,,63.99,BHO,-1.042,0.221079,0.00404515,0.812866 kka2_1:1_T146R,kka2_1:1_146,Kka2,kka2_1:1,P00552,0.812901,NO,146,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.978,-2.581,-0.397,,0.281,H,A,0.82,0.78,2.105,,92.05,BPB,-1.96833,0.520039,0.00606474,0.812901 beta-lactamase_I140C,beta-lactamase_140,TEM-1,beta-lactamase,P62593,0.812924,NO,140,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.733,-4.792,3.059,5.29918,0.128,H,A,1,0.41,1.16,,73.08,PHO,-1.48733,0.221079,0.00597777,0.812924 beta-lactamase_I140Q,beta-lactamase_140,TEM-1,beta-lactamase,P62593,0.812924,NO,140,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.733,-4.321,2.588,5.29918,0.128,H,A,1,0.41,1.16,,73.08,PHO,-1.48733,0.221079,0.00597777,0.812924 beta-lactamase_R159I,beta-lactamase_159,TEM-1,beta-lactamase,P62593,0.812924,NO,159,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-0.94,-4.036,3.096,5.64971,0.316,,B,0.68,-0.55,1.172,,64.34,PBH,-1.011,0.221079,0.00108472,0.812924 beta-lactamase_L146Y,beta-lactamase_146,TEM-1,beta-lactamase,P62593,0.813002,NO,146,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.462,-3.821,2.359,5.62483,0.007,H,A,1.3,-0.56,1.953,,64.69,AHP,-1.656,0.221079,0.00474542,0.813002 PSD95pdz3_K380P,PSD95pdz3_380,PSD95pdz3,PSD95pdz3,P31016,0.813013,NO,380,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.416,-3.336,1.92,5.87979,,,,,19.6722,,,,HBP,-1.391,0.0758425,0.000281399,0.813013 kka2_1:8_W91R,kka2_1:8_91,Kka2,kka2_1:8,P00552,0.813029,NO,91,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-1.178,-2.437,1.259,,0.077,E,B,1.51,0.27,2.51,,48.48,AHH,-1.51,0.100394,0.00358653,0.813029 kka2_1:8_W91R,kka2_1:8_91,Kka2,kka2_1:8,P00552,0.813029,NO,91,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-1.178,-2.437,1.259,,0.077,E,B,1.51,0.27,2.51,,48.48,AHH,-1.51,0.100394,0.00358653,0.813029 beta-lactamase_0_M66G,beta-lactamase_0_66,TEM-1,beta-lactamase_0,P62593,0.813103,NO,66,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.362,-3.751,2.389,,0.013,,A,0.55,-0.7,1.204,,73.08,OHH,-1.49567,0.0500837,0.00412876,0.813103 beta-lactamase_0_L111S,beta-lactamase_0_111,TEM-1,beta-lactamase_0,P62593,0.81311,NO,111,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.76,-3.564,1.804,,0.328,T,A,0.55,0.93,1.966,,64.34,BHP,-1.884,0.0500837,0.00480671,0.81311 beta-lactamase_L191A,beta-lactamase_191,TEM-1,beta-lactamase,P62593,0.813153,NO,191,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.087,-2.236,1.149,5.72226,,H,A,1.07,0.09,1.23,,63.29,BHH,-1.445,0.221079,0.00263549,0.813153 beta-lactamase_I3E,beta-lactamase_3,TEM-1,beta-lactamase,P62593,0.813162,NO,3,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-2.143,-3.545,1.402,,,,,,,3.946,,93.01,PHP,-2.21633,0.221079,0.00349304,0.813162 beta-lactamase_L188S,beta-lactamase_188,TEM-1,beta-lactamase,P62593,0.813165,NO,188,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.166,-3.587,2.421,5.55434,,H,A,1.07,-0.3,1.574,,60.14,PHB,-1.47033,0.221079,0.00295687,0.813165 beta-lactamase_D174N,beta-lactamase_174,TEM-1,beta-lactamase,P62593,0.813201,NO,174,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.738,-3.223,2.485,5.44133,0.238,,B,1.22,-0.1,,,,PAA,-1.91233,0.221079,0.00125633,0.813201 kka2_1:2_Y218F,kka2_1:2_218,Kka2,kka2_1:2,P00552,0.813247,NO,218,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-1.438,-2.611,1.173,,0.122,H,A,0.21,-0.69,1.022,,56.06,BHP,-1.17533,0.295029,0.0126098,0.813247 beta-lactamase_G234C,beta-lactamase_234,TEM-1,beta-lactamase,P62593,0.813267,NO,234,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.62,-5.087,4.467,4.24221,0.023,E,B,0.46,-0.86,,,,POH,-1.25733,0.221079,0.000889577,0.813267 beta-lactamase_L150W,beta-lactamase_150,TEM-1,beta-lactamase,P62593,0.813309,NO,150,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.326,-5.247,3.921,5.15566,,H,A,1.75,-0.2,1.615,,62.94,HHB,-1.86167,0.221079,0.00463171,0.813309 kka2_1:1_G21D,kka2_1:1_21,Kka2,kka2_1:1,P00552,0.813323,NO,21,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.368,-1.988,0.62,,0.586,T,l,0.29,-0.75,10.291,10.291,71.59,HOH,-2.10167,0.520039,0.00709648,0.813323 beta-lactamase_L55A,beta-lactamase_55,TEM-1,beta-lactamase,P62593,0.813326,NO,55,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.86,-2.512,0.652,,0.372,E,A,1.07,-0.36,1.423,,63.99,HHA,-2.247,0.221079,0.00403741,0.813326 beta-lactamase_0_D252E,beta-lactamase_0_252,TEM-1,beta-lactamase_0,P62593,0.813352,NO,252,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.0500837,0.00575769,0.813352 Pab1_V171L,Pab1_171,Pab1,Pab1,P04147,0.813498,NO,171,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.113,-2.5,1.387,,0.008,E,b,0.23,-0.34,,,,HHB,-1.19733,0.175299,0.000298662,0.813498 beta-lactamase_0_I171L,beta-lactamase_0_171,TEM-1,beta-lactamase_0,P62593,0.813511,NO,171,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-2.431,-1.98,-0.451,,0.361,,B,0.48,0.53,16.954,16.954,77.62,HHO,-1.55533,0.0500837,0.00623355,0.813511 kka2_1:2_A87V,kka2_1:2_87,Kka2,kka2_1:2,P00552,0.813529,NO,87,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.917,-3.732,1.815,,1.039,S,L,0.46,1.57,22.675,22.675,65.53,AHO,-1.822,0.295029,0.00791281,0.813529 beta-lactamase_G141S,beta-lactamase_141,TEM-1,beta-lactamase,P62593,0.813535,NO,141,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.828,-3.221,2.393,5.03155,0.575,T,l,0.76,-0.28,0.198,,64.69,HOO,-1.08933,0.221079,0.0012419,0.813535 beta-lactamase_T27Q,beta-lactamase_27,TEM-1,beta-lactamase,P62593,0.813535,NO,27,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.905,-3.929,2.024,5.39752,0.007,H,A,0.69,-0.37,0.745,,93.01,APH,-1.97933,0.221079,0.00306559,0.813535 beta-lactamase_0_R273E,beta-lactamase_0_273,TEM-1,beta-lactamase_0,P62593,0.813562,NO,273,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.314,-2.209,-0.105,,0.564,H,A,1.2,1.57,20.248,20.248,73.78,ABP,-1.841,0.0500837,0.0077952,0.813562 beta-lactamase_D174Q,beta-lactamase_174,TEM-1,beta-lactamase,P62593,0.813568,NO,174,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.738,-3.674,2.936,5.44133,0.238,,B,1.22,-0.1,,,,PAA,-1.91233,0.221079,0.00125633,0.813568 beta-lactamase_0_Q97P,beta-lactamase_0_97,TEM-1,beta-lactamase_0,P62593,0.813601,NO,97,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.072,-2.583,0.511,,0.823,G,A,0.64,2.42,16.954,16.954,77.62,PPP,-2.43833,0.0500837,0.0045116,0.813601 beta-lactamase_0_R81V,beta-lactamase_0_81,TEM-1,beta-lactamase_0,P62593,0.813658,NO,81,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.466,-3.685,2.219,,0.218,H,A,1.2,1.66,0.332,,50,PBH,-1.60667,0.0500837,0.00499763,0.813658 beta-lactamase_0_D48L,beta-lactamase_0_48,TEM-1,beta-lactamase_0,P62593,0.813685,NO,48,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.101,-3.744,2.643,,0.189,E,B,0.75,0.21,17.825,17.825,50.35,HAH,-1.62467,0.0500837,0.0027273,0.813685 beta-lactamase_0_I125N,beta-lactamase_0_125,TEM-1,beta-lactamase_0,P62593,0.813688,NO,125,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.441,-4.089,2.648,,,H,A,0.48,-0.7,1.874,,63.29,HHP,-1.248,0.0500837,0.00383964,0.813688 beta-lactamase_156_A40P,beta-lactamase_156_40,TEM-1,beta-lactamase_156,P62593,0.813723,NO,40,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.402,-3.856,2.454,,0.155,S,B,0.46,0.21,1.357,,73.78,OHB,-1.40267,0.111618,0.00490026,0.813723 kka2_1:2_A71V,kka2_1:2_71,Kka2,kka2_1:2,P00552,0.813754,NO,71,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.824,-3.693,1.869,,0.553,H,A,0.46,0.08,9.788,,64.39,HHP,-1.74033,0.295029,0.00727707,0.813754 beta-lactamase_39_S128T,beta-lactamase_39_128,TEM-1,beta-lactamase_39,P62593,0.813814,NO,128,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-0.84,-2.971,2.131,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.0495842,0.00071483,0.813814 beta-lactamase_0_A133E,beta-lactamase_0_133,TEM-1,beta-lactamase_0,P62593,0.813898,NO,133,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.186,-3.597,2.411,,,H,A,0.46,-0.86,2.148,,67.83,HHP,-0.988333,0.0500837,0.00468022,0.813898 WW_domain_T198W,WW_domain_198,Yap65,WW_domain,P46937,0.813949,NO,198,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.451,-5.08,3.629,5.14348,,,,,,3.158,,70.04,PPH,-1.513,0.153962,0.00224534,0.813949 beta-lactamase_156_L191N,beta-lactamase_156_191,TEM-1,beta-lactamase_156,P62593,0.813951,NO,191,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.087,-4.164,3.077,,,H,A,0.55,0.09,1.372,,63.29,BHH,-1.445,0.111618,0.00263549,0.813951 beta-lactamase_0_P255I,beta-lactamase_0_255,TEM-1,beta-lactamase_0,P62593,0.813966,NO,255,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.0500837,0.00499612,0.813966 beta-lactamase_A246E,beta-lactamase_246,TEM-1,beta-lactamase,P62593,0.813966,NO,246,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.121,-3.906,1.785,4.78979,0.01,E,B,0.52,-1.01,1.26,,73.78,HHH,-1.55633,0.221079,0.00569458,0.813966 beta-lactamase_0_G52E,beta-lactamase_0_52,TEM-1,beta-lactamase_0,P62593,0.813983,NO,52,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.149,-3.424,2.275,,0.299,,l,0.29,-0.04,1.164,,64.69,POB,-1.66267,0.0500837,0.00340138,0.813983 beta-lactamase_2500_T126I,beta-lactamase_2500_126,TEM-1,beta-lactamase_2500,P62593,0.814005,NO,126,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.122,-3.78,2.658,,0.05,H,A,0.22,-0.05,0.817,,44.41,HPH,-1.60467,0.361275,0.00244552,0.814005 beta-lactamase_0_A282P,beta-lactamase_0_282,TEM-1,beta-lactamase_0,P62593,0.814025,NO,282,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.0500837,0.0449821,0.814025 beta-lactamase_39_N274W,beta-lactamase_39_274,TEM-1,beta-lactamase_39,P62593,0.814073,NO,274,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.0495842,0.0110418,0.814073 beta-lactamase_E277W,beta-lactamase_277,TEM-1,beta-lactamase,P62593,0.814074,NO,277,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.869,-5.487,3.618,5.51786,0.545,H,A,0.52,-0.01,2.022,,77.62,HAH,-1.45367,0.221079,0.0169305,0.814074 beta-lactamase_S104G,beta-lactamase_104,TEM-1,beta-lactamase,P62593,0.814113,NO,104,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.015,-3.017,2.002,4.92365,0.04,,b,0.82,0.57,4.02,,63.29,HPO,-1.05267,0.221079,0.00218083,0.814113 beta-lactamase_0_V82T,beta-lactamase_0_82,TEM-1,beta-lactamase_0,P62593,0.814129,NO,82,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.325,-3.392,2.067,,0.267,H,A,0.44,0.08,1.893,,93.01,BHA,-1.28567,0.0500837,0.00397046,0.814129 kka2_1:4_G233V,kka2_1:4_233,Kka2,kka2_1:4,P00552,0.814186,NO,233,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.748,-3.827,3.079,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.168804,0.00232366,0.814186 beta-lactamase_0_N98Y,beta-lactamase_0_98,TEM-1,beta-lactamase_0,P62593,0.814233,NO,98,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-2.973,-4.22,1.247,,0.963,G,A,0.61,1.35,14.853,14.853,77.62,PPA,-2.07867,0.0500837,0.00505389,0.814233 beta-lactamase_625_R91V,beta-lactamase_625_91,TEM-1,beta-lactamase_625,P62593,0.814235,NO,91,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.392,-3.661,2.269,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.213352,0.00380226,0.814235 beta-lactamase_0_A246H,beta-lactamase_0_246,TEM-1,beta-lactamase_0,P62593,0.814264,NO,246,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.121,-4.964,2.843,,0.01,E,B,0.46,-1.01,1.201,,73.78,HHH,-1.55633,0.0500837,0.00569458,0.814264 beta-lactamase_H24P,beta-lactamase_24,TEM-1,beta-lactamase,P62593,0.814272,NO,24,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-2.481,-3.827,1.346,5.82767,,,,,,2.708,,93.01,HBO,-1.85167,0.221079,0.00238894,0.814272 kka2_1:8_E182S,kka2_1:8_182,Kka2,kka2_1:8,P00552,0.814275,NO,182,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.516,-3.382,1.866,,0.326,,B,1.52,0.75,2.568,,65.53,OAA,-1.806,0.100394,0.00641548,0.814275 kka2_1:8_E182S,kka2_1:8_182,Kka2,kka2_1:8,P00552,0.814275,NO,182,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.516,-3.382,1.866,,0.326,,B,1.52,0.75,2.568,,65.53,OAA,-1.806,0.100394,0.00641548,0.814275 beta-lactamase_0_P217F,beta-lactamase_0_217,TEM-1,beta-lactamase_0,P62593,0.814303,NO,217,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-2.062,-4.432,2.37,,0.496,I,A,0.52,-0.33,1.087,,74.48,OOH,-1.64333,0.0500837,0.00463211,0.814303 beta-lactamase_0_V82L,beta-lactamase_0_82,TEM-1,beta-lactamase_0,P62593,0.814333,NO,82,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.325,-2.426,1.101,,0.267,H,A,0.44,0.08,1.893,,93.01,BHA,-1.28567,0.0500837,0.00397046,0.814333 beta-lactamase_0_T186S,beta-lactamase_0_186,TEM-1,beta-lactamase_0,P62593,0.814337,NO,186,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.522,-2.471,-0.051,,0.396,H,A,0.22,-0.28,16.606,16.606,77.62,HPP,-1.77633,0.0500837,0.00485034,0.814337 beta-lactamase_0_A170C,beta-lactamase_0_170,TEM-1,beta-lactamase_0,P62593,0.814413,NO,170,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.237,-4.736,3.499,,0.126,,L,0.46,-0.35,2.427,,64.69,AHH,-1.63267,0.0500837,0.00431903,0.814413 kka2_1:8_D183F,kka2_1:8_183,Kka2,kka2_1:8,P00552,0.814419,NO,183,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.204,-4.408,3.204,,0.518,.,b,0.75,0.25,0.347,,52.27,AAH,-1.40533,0.100394,0.00426304,0.814419 kka2_1:8_D183F,kka2_1:8_183,Kka2,kka2_1:8,P00552,0.814419,NO,183,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.204,-4.408,3.204,,0.518,.,b,0.75,0.25,0.347,,52.27,AAH,-1.40533,0.100394,0.00426304,0.814419 Pab1_I130F,Pab1_130,Pab1,Pab1,P04147,0.814479,NO,130,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.212,-3.434,2.222,,,E,B,1.23,0.01,,,,HHB,-1.188,0.175299,0.000351112,0.814479 kka2_1:4_E182A,kka2_1:4_182,Kka2,kka2_1:4,P00552,0.814486,NO,182,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.516,-2.542,1.026,,0.326,.,B,1.04,0.75,4.755,,65.53,OAA,-1.806,0.168804,0.00641548,0.814486 beta-lactamase_0_A211D,beta-lactamase_0_211,TEM-1,beta-lactamase_0,P62593,0.814487,NO,211,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.896,-1.934,0.038,,0.369,T,A,0.46,-0.69,8.527,8.527,77.62,AHA,-1.94633,0.0500837,0.00648183,0.814487 Ubiquitin_D21K,Ubiquitin_21,Uba1,Ubiquitin,P0CG48,0.814516,NO,21,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.193,-3.433,2.24,4.96432,0.165,,B,0.23,-0.53,1.013,,71.82,PAP,-1.35867,0.205827,0.000465257,0.814516 Ubiquitin_E51W,Ubiquitin_51,Uba1,Ubiquitin,P0CG48,0.814516,NO,51,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.534,-5.411,3.877,5.36711,0.545,,B,,0.72,,,,HAA,-1.357,0.205827,0.000868134,0.814516 Ubiquitin_E64P,Ubiquitin_64,Uba1,Ubiquitin,P0CG48,0.814516,NO,64,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.763,-3.965,2.202,5.084,0.54,T,l,,0.79,,,,BAP,-1.64433,0.205827,0.000817406,0.814516 Ubiquitin_G35T,Ubiquitin_35,Uba1,Ubiquitin,P0CG48,0.814516,NO,35,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.171,-3.552,2.381,4.96213,0.713,,L,,0.2,,,,AOH,-1.314,0.205827,0.000648878,0.814516 Ubiquitin_G47S,Ubiquitin_47,Uba1,Ubiquitin,P0CG48,0.814516,NO,47,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.423,-2.633,1.21,5.24944,0.057,T,l,,-1.21,,,,HOB,-1.543,0.205827,0.000471587,0.814516 Ubiquitin_Q41N,Ubiquitin_41,Uba1,Ubiquitin,P0CG48,0.814516,NO,41,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-1.329,-3.534,2.205,4.9201,0.017,E,B,0.12,-0.98,0.812,,30.07,PPB,-1.55067,0.205827,0.000521668,0.814516 Ubiquitin_Y59Q,Ubiquitin_59,Uba1,Ubiquitin,P0CG48,0.814516,NO,59,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-1.307,-4.002,2.695,5.05599,0.072,G,A,0.43,-0.74,2.566,,24.53,AHP,-1.568,0.205827,0.000775084,0.814516 WW_domain_D201S,WW_domain_201,Yap65,WW_domain,P46937,0.814567,NO,201,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.369,-2.994,1.625,4.90312,,,,,,20.806,20.806,70.04,PAO,-1.456,0.153962,0.00248402,0.814567 kka2_1:8_S104I,kka2_1:8_104,Kka2,kka2_1:8,P00552,0.814622,NO,104,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.436,-3.864,2.428,,0.536,T,A,0.27,-1.11,1.689,,63.64,HPP,-1.91433,0.100394,0.00555207,0.814622 kka2_1:8_S104I,kka2_1:8_104,Kka2,kka2_1:8,P00552,0.814622,NO,104,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.436,-3.864,2.428,,0.536,T,A,0.27,-1.11,1.689,,63.64,HPP,-1.91433,0.100394,0.00555207,0.814622 beta-lactamase_156_E35H,beta-lactamase_156_35,TEM-1,beta-lactamase_156,P62593,0.814635,NO,35,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-0.869,-4.279,3.41,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.111618,0.00174441,0.814635 beta-lactamase_2500_R63T,beta-lactamase_2500_63,TEM-1,beta-lactamase_2500,P62593,0.814696,NO,63,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-0.943,-3.447,2.504,,0.218,,B,1.2,-0.31,0.929,,44.06,ABH,-0.992333,0.361275,0.00126938,0.814696 kka2_1:8_R66S,kka2_1:8_66,Kka2,kka2_1:8,P00552,0.814824,NO,66,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-0.922,-3.412,2.49,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.100394,0.00161025,0.814824 kka2_1:8_R66S,kka2_1:8_66,Kka2,kka2_1:8,P00552,0.814824,NO,66,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-0.922,-3.412,2.49,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.100394,0.00161025,0.814824 beta-lactamase_0_S256G,beta-lactamase_0_256,TEM-1,beta-lactamase_0,P62593,0.814827,NO,256,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.0500837,0.00710634,0.814827 beta-lactamase_2500_E272W,beta-lactamase_2500_272,TEM-1,beta-lactamase_2500,P62593,0.814841,NO,272,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.361275,0.00545371,0.814841 beta-lactamase_2500_S221W,beta-lactamase_2500_221,TEM-1,beta-lactamase_2500,P62593,0.814848,NO,221,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.754,-5.418,3.664,,0.624,H,A,0.27,-0.2,1.971,,74.48,BPH,-1.59967,0.361275,0.0046094,0.814848 kka2_1:8_R122D,kka2_1:8_122,Kka2,kka2_1:8,P00552,0.814865,NO,122,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.175,-2.452,0.277,,0.487,H,A,1.2,0.26,22.675,22.675,71.59,BBH,-1.53833,0.100394,0.00736512,0.814865 kka2_1:8_R122D,kka2_1:8_122,Kka2,kka2_1:8,P00552,0.814865,NO,122,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.175,-2.452,0.277,,0.487,H,A,1.2,0.26,22.675,22.675,71.59,BBH,-1.53833,0.100394,0.00736512,0.814865 beta-lactamase_0_D174A,beta-lactamase_0_174,TEM-1,beta-lactamase_0,P62593,0.81492,NO,174,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.738,-3.303,2.565,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.0500837,0.00125633,0.81492 beta-lactamase_0_R162T,beta-lactamase_0_162,TEM-1,beta-lactamase_0,P62593,0.814969,NO,162,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.016,-3.471,2.455,,0.124,S,B,1.2,-0.37,1.026,,64.69,ABH,-1.25,0.0500837,0.000561334,0.814969 beta-lactamase_0_L79C,beta-lactamase_0_79,TEM-1,beta-lactamase_0,P62593,0.814974,NO,79,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.842,-4.663,3.821,,0.007,H,A,0.55,-0.16,5.053,,50.35,HHP,-1.44333,0.0500837,0.000947397,0.814974 PSD95pdz3_A390Q,PSD95pdz3_390,PSD95pdz3,PSD95pdz3,P31016,0.815094,NO,390,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.307,-3.581,2.274,5.03823,,,,,12.46,,,,HHP,-1.54467,0.0758425,0.00104603,0.815094 kka2_1:8_L260A,kka2_1:8_260,Kka2,kka2_1:8,P00552,0.815113,NO,260,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.741,-3.106,2.365,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.100394,0.0233782,0.815113 kka2_1:8_L260A,kka2_1:8_260,Kka2,kka2_1:8,P00552,0.815113,NO,260,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.741,-3.106,2.365,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.100394,0.0233782,0.815113 beta-lactamase_0_Y262N,beta-lactamase_0_262,TEM-1,beta-lactamase_0,P62593,0.815145,NO,262,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.0500837,0.00853516,0.815145 beta-lactamase_C18Y,beta-lactamase_18,TEM-1,beta-lactamase,P62593,0.815179,NO,18,C,Y,CY,Special,Hydrophobic,5.07,5.66,0.59,194,121,181,60,108.5,193.6,85.1,-2.26,-4.189,1.929,,,,,,,3.995,,93.01,HOH,-2.093,0.221079,0.002536,0.815179 beta-lactamase_156_D48W,beta-lactamase_156_48,TEM-1,beta-lactamase_156,P62593,0.815223,NO,48,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.101,-5.502,4.401,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.111618,0.0027273,0.815223 beta-lactamase_0_L192S,beta-lactamase_0_192,TEM-1,beta-lactamase_0,P62593,0.815228,NO,192,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.254,-3.616,2.362,,0.095,H,A,0.55,0.35,1.756,,60.14,HHP,-1.41833,0.0500837,0.00558728,0.815228 kka2_1:2_P109L,kka2_1:2_109,Kka2,kka2_1:2,P00552,0.815234,NO,109,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.412,-3.58,2.168,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.295029,0.0070929,0.815234 beta-lactamase_0_W227D,beta-lactamase_0_227,TEM-1,beta-lactamase_0,P62593,0.815315,NO,227,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-0.982,-4.076,3.094,,0.272,,B,0.47,-0.29,3.782,,74.48,OHH,-1.595,0.0500837,0.00226019,0.815315 beta-lactamase_2500_L38W,beta-lactamase_2500_38,TEM-1,beta-lactamase_2500,P62593,0.815408,NO,38,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.343,-5.229,3.886,,0.088,H,A,0.55,0.2,2.71,,64.34,PHO,-1.78033,0.361275,0.00373244,0.815408 kka2_1:2_L174M,kka2_1:2_174,Kka2,kka2_1:2,P00552,0.815412,NO,174,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.952,-2.955,2.003,,,H,A,1.59,-0.31,8.521,,51.89,BHB,-2.08533,0.295029,0.00438501,0.815412 beta-lactamase_G85V,beta-lactamase_85,TEM-1,beta-lactamase,P62593,0.815466,NO,85,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.011,-3.796,2.785,5.58951,0.805,T,l,0.23,1.7,1.468,,63.64,HOP,-1.68733,0.221079,0.00252173,0.815466 Pab1_A141E,Pab1_141,Pab1,Pab1,P04147,0.815531,NO,141,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.461,-3.323,1.862,,0.34,H,A,0.52,-0.27,2.15,,79.03,BHH,-1.19433,0.175299,0.00165974,0.815531 kka2_1:2_L19R,kka2_1:2_19,Kka2,kka2_1:2,P00552,0.815562,NO,19,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.254,-4.143,2.889,,0.08,T,A,0.55,-0.26,17.165,17.165,65.53,BHH,-2.221,0.295029,0.00620703,0.815562 beta-lactamase_0_T139R,beta-lactamase_0_139,TEM-1,beta-lactamase_0,P62593,0.815648,NO,139,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.901,-2.238,0.337,,0.216,H,A,0.22,0.39,0.421,,77.62,PPH,-2.04667,0.0500837,0.00441837,0.815648 hsp90_M589E,hsp90_589,hsp90,hsp90,P02829,0.815694,NO,589,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-3.858,-2.818,0,4.72723,0.032,H,A,0.84,0.31,,,,PHA,-3.24233,0.368192,0.000222939,0.815694 beta-lactamase_F6G,beta-lactamase_6,TEM-1,beta-lactamase,P62593,0.815716,NO,6,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.847,-3.515,1.668,,,,,,,1.276,,67.83,BHB,-2.076,0.221079,0.00261627,0.815716 beta-lactamase_S264Q,beta-lactamase_264,TEM-1,beta-lactamase,P62593,0.815716,NO,264,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.985,-4.032,2.047,4.67475,0.04,,B,0.25,0.29,34.251,34.251,73.78,OPP,-2.19867,0.221079,0.0119399,0.815716 beta-lactamase_0_T69G,beta-lactamase_0_69,TEM-1,beta-lactamase_0,P62593,0.815741,NO,69,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-0.973,-3.289,2.316,,,G,A,0.22,-1.24,0.505,,93.01,PPH,-1.01833,0.0500837,0.00127498,0.815741 Pab1_N187P,Pab1_187,Pab1,Pab1,P04147,0.815794,NO,187,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-1.224,-3.69,2.466,,0.456,S,b,,1.87,,,,HPO,-1.272,0.175299,0.00083165,0.815794 kka2_1:8_G99C,kka2_1:8_99,Kka2,kka2_1:8,P00552,0.815804,NO,99,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.596,-5.115,4.519,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.100394,0.00186055,0.815804 kka2_1:8_G99C,kka2_1:8_99,Kka2,kka2_1:8,P00552,0.815804,NO,99,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.596,-5.115,4.519,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.100394,0.00186055,0.815804 beta-lactamase_2500_G265Q,beta-lactamase_2500_265,TEM-1,beta-lactamase_2500,P62593,0.815824,NO,265,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-2.58,-2.659,0.079,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.361275,0.00811926,0.815824 beta-lactamase_156_S128G,beta-lactamase_156_128,TEM-1,beta-lactamase_156,P62593,0.815825,NO,128,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-0.84,-2.908,2.068,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.111618,0.00071483,0.815825 beta-lactamase_V106G,beta-lactamase_106,TEM-1,beta-lactamase,P62593,0.815872,NO,106,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.218,-3.752,2.534,5.23115,0.258,T,A,0.96,0.24,1.188,,72.73,OHP,-1.04933,0.221079,0.00304168,0.815872 beta-lactamase_0_D129W,beta-lactamase_0_129,TEM-1,beta-lactamase_0,P62593,0.815874,NO,129,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.816,-5.545,4.729,,,,B,0.75,-0.69,2.66,,34.97,PAP,-0.818,0.0500837,0.00109178,0.815874 beta-lactamase_2500_I171P,beta-lactamase_2500_171,TEM-1,beta-lactamase_2500,P62593,0.815882,NO,171,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-2.431,-4.052,1.621,,0.361,,B,0.48,0.53,1.66,,77.62,HHO,-1.55533,0.361275,0.00623355,0.815882 beta-lactamase_0_Y95P,beta-lactamase_0_95,TEM-1,beta-lactamase_0,P62593,0.815885,NO,95,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-1.715,-4.285,2.57,,0.122,,b,0.21,-0.37,2.914,,77.62,BHP,-2.16167,0.0500837,0.00479449,0.815885 beta-lactamase_2500_D161N,beta-lactamase_2500_161,TEM-1,beta-lactamase_2500,P62593,0.815927,NO,161,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.891,-3.293,2.402,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.361275,0.000897697,0.815927 beta-lactamase_39_A211C,beta-lactamase_39_211,TEM-1,beta-lactamase_39,P62593,0.815978,NO,211,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.896,-5.066,3.17,,0.369,T,A,0.46,-0.69,1.419,,77.62,AHA,-1.94633,0.0495842,0.00648183,0.815978 Pab1_A199L,Pab1_199,Pab1,Pab1,P04147,0.816044,NO,199,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.53,-3.34,1.81,,,,,,,1.479,,80.42,HHO,-1.50467,0.175299,0.00145024,0.816044 PSD95pdz3_R318W,PSD95pdz3_318,PSD95pdz3,PSD95pdz3,P31016,0.81606,NO,318,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.582,-5.004,3.422,4.94876,,,,,17.5609,,,,BBO,-1.40567,0.0758425,0.00110471,0.81606 beta-lactamase_0_T107F,beta-lactamase_0_107,TEM-1,beta-lactamase_0,P62593,0.816063,NO,107,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.117,-4.119,3.002,,,G,A,0.22,-0.06,3.73,,67.83,HPA,-1.265,0.0500837,0.00239347,0.816063 beta-lactamase_0_S57V,beta-lactamase_0_57,TEM-1,beta-lactamase_0,P62593,0.816092,NO,57,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.918,-2.889,0.971,,0.352,E,B,0.27,-0.18,1.454,,72.73,APH,-2.29167,0.0500837,0.00492804,0.816092 kka2_1:4_G151W,kka2_1:4_151,Kka2,kka2_1:4,P00552,0.816125,NO,151,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.873,-5.3,4.427,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.168804,0.00339918,0.816125 beta-lactamase_0_L284R,beta-lactamase_0_284,TEM-1,beta-lactamase_0,P62593,0.816137,NO,284,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.981,,,,0.848,H,A,2.89,0.67,4.544,,77.62,PHH,-1.82133,0.0500837,0.0686156,0.816137 beta-lactamase_R159A,beta-lactamase_159,TEM-1,beta-lactamase,P62593,0.816182,NO,159,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-0.94,-3.127,2.187,5.64971,0.316,,B,0.68,-0.55,1.172,,64.34,PBH,-1.011,0.221079,0.00108472,0.816182 beta-lactamase_0_G114A,beta-lactamase_0_114,TEM-1,beta-lactamase_0,P62593,0.816222,NO,114,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.094,-2.444,1.35,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.0500837,0.00224919,0.816222 beta-lactamase_L120I,beta-lactamase_120,TEM-1,beta-lactamase,P62593,0.816243,NO,120,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.044,-2.541,1.497,5.11974,,H,A,1.3,-1.13,1.988,,64.69,AHO,-1.13633,0.221079,0.00143563,0.816243 beta-lactamase_R176D,beta-lactamase_176,TEM-1,beta-lactamase,P62593,0.81628,NO,176,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-0.863,-3.694,2.831,5.61264,0.385,T,B,0.68,-0.63,,,,ABA,-1.38867,0.221079,0.00105554,0.81628 beta-lactamase_156_S104K,beta-lactamase_156_104,TEM-1,beta-lactamase_156,P62593,0.816294,NO,104,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.015,-3.372,2.357,,0.04,,b,0.27,0.57,4.02,,63.29,HPO,-1.05267,0.111618,0.00218083,0.816294 kka2_1:2_R143G,kka2_1:2_143,Kka2,kka2_1:2,P00552,0.816298,NO,143,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.525,-3.627,1.102,,0.325,H,A,0.16,1.22,14.853,14.853,65.53,ABH,-1.86833,0.295029,0.00662247,0.816298 beta-lactamase_0_E46P,beta-lactamase_0_46,TEM-1,beta-lactamase_0,P62593,0.816304,NO,46,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.94,-4.039,2.099,,0.021,E,B,1.04,0.14,30.306,30.306,59.44,HAH,-2.079,0.0500837,0.00427568,0.816304 beta-lactamase_0_A133T,beta-lactamase_0_133,TEM-1,beta-lactamase_0,P62593,0.816311,NO,133,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.186,-2.382,1.196,,,H,A,0.46,-0.86,2.148,,67.83,HHP,-0.988333,0.0500837,0.00468022,0.816311 kka2_1:1_R18S,kka2_1:1_18,Kka2,kka2_1:1,P00552,0.816311,NO,18,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.055,-2.892,0.837,,0.474,T,A,1.2,0.54,11.422,11.422,71.59,ABH,-1.821,0.520039,0.00724065,0.816311 kka2_1:8_F203V,kka2_1:8_203,Kka2,kka2_1:8,P00552,0.816322,NO,203,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-0.911,-3.287,2.376,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.100394,0.00318738,0.816322 kka2_1:8_F203V,kka2_1:8_203,Kka2,kka2_1:8,P00552,0.816322,NO,203,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-0.911,-3.287,2.376,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.100394,0.00318738,0.816322 beta-lactamase_P143C,beta-lactamase_143,TEM-1,beta-lactamase,P62593,0.816323,NO,143,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.967,-5.012,4.045,5.16366,0.075,H,A,0.99,-0.37,0.479,,66.78,OOB,-1.354,0.221079,0.00114551,0.816323 beta-lactamase_2500_M209L,beta-lactamase_2500_209,TEM-1,beta-lactamase_2500,P62593,0.816362,NO,209,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.442,-1.689,0.247,,,H,A,0.55,-0.97,3.229,,64.69,HHA,-1.52633,0.361275,0.00625021,0.816362 kka2_1:1_L53S,kka2_1:1_53,Kka2,kka2_1:1,P00552,0.816377,NO,53,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-2.681,-2.891,0.21,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.520039,0.00671168,0.816377 beta-lactamase_0_T27D,beta-lactamase_0_27,TEM-1,beta-lactamase_0,P62593,0.816429,NO,27,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.905,-3.5,1.595,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.0500837,0.00306559,0.816429 kka2_1:1_I2M,kka2_1:1_2,Kka2,kka2_1:1,P00552,0.816437,NO,2,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.787,-3.979,2.192,,,,,,,2.329,,71.59,HHA,-1.92433,0.520039,0.00246644,0.816437 beta-lactamase_156_L73E,beta-lactamase_156_73,TEM-1,beta-lactamase_156,P62593,0.816486,NO,73,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.507,-3.924,2.417,,,H,A,0.55,-0.64,2.09,,67.83,HHH,-1.487,0.111618,0.00488983,0.816486 kka2_1:4_D156P,kka2_1:4_156,Kka2,kka2_1:4,P00552,0.816529,NO,156,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.696,-3.904,2.208,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.168804,0.00926998,0.816529 kka2_1:4_I254D,kka2_1:4_254,Kka2,kka2_1:4,P00552,0.816594,NO,254,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.933,-4.156,2.223,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.168804,0.0132375,0.816594 WW_domain_D201N,WW_domain_201,Yap65,WW_domain,P46937,0.816617,NO,201,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.369,-3.205,1.836,4.90312,,,,,,20.806,20.806,70.04,PAO,-1.456,0.153962,0.00248402,0.816617 beta-lactamase_0_P165L,beta-lactamase_0_165,TEM-1,beta-lactamase_0,P62593,0.81664,NO,165,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.373,-3.388,2.015,,0.203,T,A,0.52,-0.31,3.242,,73.78,AOA,-1.359,0.0500837,0.00549538,0.81664 beta-lactamase_V42T,beta-lactamase_42,TEM-1,beta-lactamase,P62593,0.816643,NO,42,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.564,-3.48,1.916,5.27904,0.017,E,B,1.64,-0.51,2.024,,63.99,BHO,-1.042,0.221079,0.00404515,0.816643 kka2_1:1_S40Q,kka2_1:1_40,Kka2,kka2_1:1,P00552,0.816665,NO,40,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.645,-2.827,0.182,,0.32,E,B,0.27,-0.9,25.997,25.997,71.59,HPH,-1.91567,0.520039,0.00693477,0.816665 kka2_1:2_A117V,kka2_1:2_117,Kka2,kka2_1:2,P00552,0.816697,NO,117,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.828,-2.25,1.422,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.295029,0.00282984,0.816697 beta-lactamase_0_H287I,beta-lactamase_0_287,TEM-1,beta-lactamase_0,P62593,0.816742,NO,287,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,,,,,,,,,,,,,BBH,-1.111,0.0500837,,0.816742 beta-lactamase_625_L137Q,beta-lactamase_625_137,TEM-1,beta-lactamase_625,P62593,0.816802,NO,137,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.03,-4.147,3.117,,,H,A,0.55,-0.38,1.5,,42.31,HHP,-1.58933,0.213352,0.00278599,0.816802 PSD95pdz3_S339E,PSD95pdz3_339,PSD95pdz3,PSD95pdz3,P31016,0.816845,NO,339,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.519,-2.897,1.378,5.34493,,,,,12.2167,,,,HPH,-1.55767,0.0758425,0.00084982,0.816845 kka2_1:2_A150F,kka2_1:2_150,Kka2,kka2_1:2,P00552,0.816849,NO,150,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.949,-4.228,3.279,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.295029,0.0045009,0.816849 WW_domain_Q186L,WW_domain_186,Yap65,WW_domain,P46937,0.816859,NO,186,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-1.358,-3.135,1.777,4.88854,,,,,,,,,OPB,-1.207,0.153962,0.00161546,0.816859 beta-lactamase_F22T,beta-lactamase_22,TEM-1,beta-lactamase,P62593,0.816948,NO,22,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-2.676,-2.592,-0.084,,,,,,,1.616,,73.08,HHH,-2.03233,0.221079,0.00262842,0.816948 beta-lactamase_2500_I280L,beta-lactamase_2500_280,TEM-1,beta-lactamase_2500,P62593,0.81698,NO,280,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.361275,0.0530888,0.81698 beta-lactamase_0_P250E,beta-lactamase_0_250,TEM-1,beta-lactamase_0,P62593,0.816988,NO,250,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.0500837,0.00550899,0.816988 beta-lactamase_0_L74K,beta-lactamase_0_74,TEM-1,beta-lactamase_0,P62593,0.817003,NO,74,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.296,-3.688,2.392,,,H,A,0.55,-0.91,1.46,,50,HHO,-1.34933,0.0500837,0.00493255,0.817003 beta-lactamase_L137A,beta-lactamase_137,TEM-1,beta-lactamase,P62593,0.817025,NO,137,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.03,-3.142,2.112,5.20117,,H,A,1.07,-0.38,0.674,,42.31,HHP,-1.58933,0.221079,0.00278599,0.817025 beta-lactamase_2500_G39F,beta-lactamase_2500_39,TEM-1,beta-lactamase_2500,P62593,0.817073,NO,39,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.864,-4.451,2.587,,0.701,T,L,0.29,0.47,29.926,29.926,77.62,HOH,-1.53633,0.361275,0.00487611,0.817073 beta-lactamase_0_K32H,beta-lactamase_0_32,TEM-1,beta-lactamase_0,P62593,0.817085,NO,32,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.984,-4.632,2.648,,0.563,H,A,2.34,0.34,0.418,,73.08,HBA,-2.04233,0.0500837,0.00401283,0.817085 beta-lactamase_0_W208L,beta-lactamase_0_208,TEM-1,beta-lactamase_0,P62593,0.817085,NO,208,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-0.818,-3.358,2.54,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.0500837,0.00126609,0.817085 beta-lactamase_L167S,beta-lactamase_167,TEM-1,beta-lactamase,P62593,0.81709,NO,167,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.138,-2.747,1.609,5.13111,0.015,G,A,0.08,-0.63,0.4,,64.69,AHP,-1.30767,0.221079,0.00303566,0.81709 kka2_1:8_L39M,kka2_1:8_39,Kka2,kka2_1:8,P00552,0.817097,NO,39,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.223,-4.14,2.917,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.100394,0.00493618,0.817097 kka2_1:8_L39M,kka2_1:8_39,Kka2,kka2_1:8,P00552,0.817097,NO,39,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.223,-4.14,2.917,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.100394,0.00493618,0.817097 beta-lactamase_0_F64Q,beta-lactamase_0_64,TEM-1,beta-lactamase_0,P62593,0.817109,NO,64,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-0.841,-4.349,3.508,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.0500837,0.000947691,0.817109 kka2_1:1_M178C,kka2_1:1_178,Kka2,kka2_1:1,P00552,0.817115,NO,178,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-3.206,-3.246,0.04,,0.554,.,b,0.55,0.68,3.152,,71.59,BHO,-2.154,0.520039,0.00717253,0.817115 beta-lactamase_2500_L284C,beta-lactamase_2500_284,TEM-1,beta-lactamase_2500,P62593,0.817193,NO,284,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.361275,0.0686156,0.817193 kka2_1:4_T187V,kka2_1:4_187,Kka2,kka2_1:4,P00552,0.817241,NO,187,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.273,-3.25,1.977,,0.007,E,B,0.22,-0.85,2.73,,52.27,HPB,-1.06567,0.168804,0.00693073,0.817241 beta-lactamase_N272E,beta-lactamase_272,TEM-1,beta-lactamase,P62593,0.817268,NO,272,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-1.127,-2.497,1.37,5.37826,0.081,H,A,0.09,-0.97,1.468,,63.64,BPB,-1.56333,0.221079,0.00545371,0.817268 beta-lactamase_2500_R92A,beta-lactamase_2500_92,TEM-1,beta-lactamase_2500,P62593,0.817357,NO,92,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.718,-2.705,0.987,,0.479,E,B,1.2,1.36,3.069,,65.38,BBH,-1.50367,0.361275,0.00429626,0.817357 kka2_1:4_W24Q,kka2_1:4_24,Kka2,kka2_1:4,P00552,0.817485,NO,24,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-1.779,-4.365,2.586,,0.477,E,B,1.51,-0.21,2.666,,56.06,AHH,-2.24467,0.168804,0.00631564,0.817485 PSD95pdz3_E373Y,PSD95pdz3_373,PSD95pdz3,PSD95pdz3,P31016,0.817543,NO,373,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.404,-3.844,2.44,5.79743,,,,,27.9833,,,,BAP,-1.57667,0.0758425,0.000387698,0.817543 kka2_1:8_L184T,kka2_1:8_184,Kka2,kka2_1:8,P00552,0.817559,NO,184,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.496,-3.677,2.181,,0.489,E,B,0.55,-0.06,4.495,,63.26,AHH,-1.24833,0.100394,0.00518742,0.817559 kka2_1:8_L184T,kka2_1:8_184,Kka2,kka2_1:8,P00552,0.817559,NO,184,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.496,-3.677,2.181,,0.489,E,B,0.55,-0.06,4.495,,63.26,AHH,-1.24833,0.100394,0.00518742,0.817559 beta-lactamase_0_T186A,beta-lactamase_0_186,TEM-1,beta-lactamase_0,P62593,0.81759,NO,186,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.522,-1.898,-0.624,,0.396,H,A,0.22,-0.28,16.606,16.606,77.62,HPP,-1.77633,0.0500837,0.00485034,0.81759 beta-lactamase_0_L47D,beta-lactamase_0_47,TEM-1,beta-lactamase_0,P62593,0.817594,NO,47,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.876,-3.931,2.055,,0.007,E,B,0.55,0.2,1.024,,67.83,AHA,-1.639,0.0500837,0.00439844,0.817594 kka2_1:4_D101H,kka2_1:4_101,Kka2,kka2_1:4,P00552,0.817601,NO,101,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.028,-4.537,3.509,,0.213,E,B,0.75,-1.24,8.707,,63.64,PAH,-1.534,0.168804,0.00423361,0.817601 kka2_1:4_L39A,kka2_1:4_39,Kka2,kka2_1:4,P00552,0.817629,NO,39,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.223,-2.615,1.392,,,E,B,0.55,-1.21,1.998,,71.59,BHP,-1.69167,0.168804,0.00493618,0.817629 beta-lactamase_2500_A278N,beta-lactamase_2500_278,TEM-1,beta-lactamase_2500,P62593,0.81768,NO,278,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.361275,0.0310297,0.81768 beta-lactamase_625_G76F,beta-lactamase_625_76,TEM-1,beta-lactamase_625,P62593,0.81768,NO,76,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.189,-4.264,3.075,,,H,A,0.29,-0.67,3.059,,67.83,OOH,-1.22267,0.213352,0.00476637,0.81768 PSD95pdz3_F337Q,PSD95pdz3_337,PSD95pdz3,PSD95pdz3,P31016,0.817805,NO,337,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.524,-4.031,2.507,5.22838,,,,,13.4936,,,,HHH,-1.59467,0.0758425,0.000875287,0.817805 beta-lactamase_T261E,beta-lactamase_261,TEM-1,beta-lactamase,P62593,0.817811,NO,261,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.88,-3.93,1.05,5.65483,0.014,E,B,0.53,-0.39,2.449,,77.62,HPP,-1.771,0.221079,0.0123091,0.817811 beta-lactamase_2500_G85F,beta-lactamase_2500_85,TEM-1,beta-lactamase_2500,P62593,0.817827,NO,85,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.011,-4.377,3.366,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.361275,0.00252173,0.817827 kka2_1:4_Q26C,kka2_1:4_26,Kka2,kka2_1:4,P00552,0.817831,NO,26,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.18,-5.205,3.025,,0.448,E,B,0.4,0.44,5.022,,92.05,HPP,-2.11167,0.168804,0.00708962,0.817831 beta-lactamase_2500_E279C,beta-lactamase_2500_279,TEM-1,beta-lactamase_2500,P62593,0.817841,NO,279,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.361275,0.0192826,0.817841 beta-lactamase_0_W208R,beta-lactamase_0_208,TEM-1,beta-lactamase_0,P62593,0.817873,NO,208,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-0.818,-4.158,3.34,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.0500837,0.00126609,0.817873 beta-lactamase_D83S,beta-lactamase_83,TEM-1,beta-lactamase,P62593,0.817896,NO,83,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.066,-2.542,1.476,5.40616,0.354,H,A,1.33,0.22,0.861,,48.95,HAH,-1.34733,0.221079,0.00205968,0.817896 beta-lactamase_R92G,beta-lactamase_92,TEM-1,beta-lactamase,P62593,0.81794,NO,92,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.718,-3.552,1.834,5.65832,0.479,E,B,0.91,1.36,3.069,,65.38,BBH,-1.50367,0.221079,0.00429626,0.81794 kka2_1:1_L107P,kka2_1:1_107,Kka2,kka2_1:1,P00552,0.817952,NO,107,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.238,-4.14,2.902,,0.197,.,B,0.55,-1.1,3.542,,71.59,BHH,-2.143,0.520039,0.00561937,0.817952 kka2_1:2_M148I,kka2_1:2_148,Kka2,kka2_1:2,P00552,0.817966,NO,148,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.847,-2.616,0.769,,0.268,H,A,1.59,0.71,1.439,,64.39,BHA,-1.65467,0.295029,0.00982664,0.817966 beta-lactamase_0_W208D,beta-lactamase_0_208,TEM-1,beta-lactamase_0,P62593,0.817977,NO,208,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-0.818,-4.144,3.326,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.0500837,0.00126609,0.817977 WW_domain_Q200L,WW_domain_200,Yap65,WW_domain,P46937,0.817998,NO,200,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-1.599,-3.247,1.648,5.37476,,,,,,1.9,,70.04,HPA,-1.484,0.153962,0.00300397,0.817998 beta-lactamase_156_S201D,beta-lactamase_156_201,TEM-1,beta-lactamase_156,P62593,0.818008,NO,201,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.183,-3.453,2.27,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.111618,0.00198815,0.818008 beta-lactamase_0_Q97R,beta-lactamase_0_97,TEM-1,beta-lactamase_0,P62593,0.818053,NO,97,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.072,-2.428,0.356,,0.823,G,A,0.64,2.42,16.954,16.954,77.62,PPP,-2.43833,0.0500837,0.0045116,0.818053 beta-lactamase_0_T263P,beta-lactamase_0_263,TEM-1,beta-lactamase_0,P62593,0.818083,NO,263,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.0500837,0.0110582,0.818083 beta-lactamase_V257T,beta-lactamase_257,TEM-1,beta-lactamase,P62593,0.818127,NO,257,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.533,-2.697,1.164,5.31999,,E,B,0.96,-0.7,1.463,,58.74,HHH,-1.70967,0.221079,0.00756629,0.818127 PSD95pdz3_G324N,PSD95pdz3_324,PSD95pdz3,PSD95pdz3,P31016,0.818142,NO,324,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.008,-3.13,2.122,4.98881,,,,,10.4525,,,,HOH,-1.293,0.0758425,0.00103462,0.818142 beta-lactamase_625_P250G,beta-lactamase_625_250,TEM-1,beta-lactamase_625,P62593,0.818154,NO,250,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.213352,0.00550899,0.818154 kka2_1:8_F133H,kka2_1:8_133,Kka2,kka2_1:8,P00552,0.818242,NO,133,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-0.871,-4.414,3.543,,0.178,,B,1.62,0.43,1.816,,42.42,OHA,-0.871667,0.100394,0.00182168,0.818242 kka2_1:8_F133H,kka2_1:8_133,Kka2,kka2_1:8,P00552,0.818242,NO,133,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-0.871,-4.414,3.543,,0.178,,B,1.62,0.43,1.816,,42.42,OHA,-0.871667,0.100394,0.00182168,0.818242 kka2_1:8_A117Q,kka2_1:8_117,Kka2,kka2_1:8,P00552,0.818328,NO,117,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.828,-3.991,3.163,,,H,A,1.04,-0.78,0.755,,45.83,HHA,-1.79333,0.100394,0.00282984,0.818328 kka2_1:8_A117Q,kka2_1:8_117,Kka2,kka2_1:8,P00552,0.818328,NO,117,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.828,-3.991,3.163,,,H,A,1.04,-0.78,0.755,,45.83,HHA,-1.79333,0.100394,0.00282984,0.818328 kka2_1:8_Q100W,kka2_1:8_100,Kka2,kka2_1:8,P00552,0.818328,NO,100,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.77,-5.568,2.798,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.100394,0.0066405,0.818328 kka2_1:8_Q100W,kka2_1:8_100,Kka2,kka2_1:8,P00552,0.818328,NO,100,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.77,-5.568,2.798,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.100394,0.0066405,0.818328 kka2_1:8_G88L,kka2_1:8_88,Kka2,kka2_1:8,P00552,0.818332,NO,88,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.689,-3.754,2.065,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.100394,0.00685559,0.818332 kka2_1:8_G88L,kka2_1:8_88,Kka2,kka2_1:8,P00552,0.818332,NO,88,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.689,-3.754,2.065,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.100394,0.00685559,0.818332 beta-lactamase_0_R202Q,beta-lactamase_0_202,TEM-1,beta-lactamase_0,P62593,0.818355,NO,202,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.292,-1.95,0.658,,0.188,H,A,1.2,0.62,7.016,,77.62,PBP,-1.54767,0.0500837,0.00321899,0.818355 kka2_1:8_C209S,kka2_1:8_209,Kka2,kka2_1:8,P00552,0.818385,NO,209,C,S,CS,Special,Polar,5.07,5.68,0.61,112,121,105,-16,108.5,89,-19.5,-0.906,-3.458,2.552,,,,a,1.5,-0.89,0.391,,19.32,AOO,-0.903,0.100394,0.00260862,0.818385 kka2_1:8_C209S,kka2_1:8_209,Kka2,kka2_1:8,P00552,0.818385,NO,209,C,S,CS,Special,Polar,5.07,5.68,0.61,112,121,105,-16,108.5,89,-19.5,-0.906,-3.458,2.552,,,,a,1.5,-0.89,0.391,,19.32,AOO,-0.903,0.100394,0.00260862,0.818385 beta-lactamase_G154C,beta-lactamase_154,TEM-1,beta-lactamase,P62593,0.818386,NO,154,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.823,-5.058,4.235,5.40944,0.54,T,l,0.77,-0.56,2.283,,64.69,HOA,-1.635,0.221079,0.00180205,0.818386 beta-lactamase_L38D,beta-lactamase_38,TEM-1,beta-lactamase,P62593,0.818411,NO,38,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.343,-3.97,2.627,5.23728,0.088,H,A,1.75,0.2,1.986,,64.34,PHO,-1.78033,0.221079,0.00373244,0.818411 beta-lactamase_I93F,beta-lactamase_93,TEM-1,beta-lactamase,P62593,0.818427,NO,93,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.401,-3.88,2.479,5.74695,0.128,E,B,0.77,0.44,1.757,,67.83,BHB,-1.873,0.221079,0.00527066,0.818427 beta-lactamase_0_Q88F,beta-lactamase_0_88,TEM-1,beta-lactamase_0,P62593,0.818499,NO,88,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.086,-4.377,2.291,,0.807,,B,0.64,2.03,0.4,,77.62,APH,-1.53433,0.0500837,0.00504167,0.818499 kka2_1:4_M116T,kka2_1:4_116,Kka2,kka2_1:4,P00552,0.818526,NO,116,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-2.482,-2.959,0.477,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.168804,0.00745147,0.818526 beta-lactamase_0_T107M,beta-lactamase_0_107,TEM-1,beta-lactamase_0,P62593,0.818533,NO,107,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.117,-4.531,3.414,,,G,A,0.22,-0.06,3.73,,67.83,HPA,-1.265,0.0500837,0.00239347,0.818533 beta-lactamase_0_R176P,beta-lactamase_0_176,TEM-1,beta-lactamase_0,P62593,0.818584,NO,176,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-0.863,-3.88,3.017,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.0500837,0.00105554,0.818584 gb1_A252V,gb1_252,gb1,gb1,P06654,0.818651,NO,252,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.175,-2.814,1.639,,,,,,,,,,PHA,-1.55967,0.177985,0.00125598,0.818651 beta-lactamase_0_P25N,beta-lactamase_0_25,TEM-1,beta-lactamase_0,P62593,0.81868,NO,25,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.526,-3.702,2.176,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.0500837,0.00347571,0.81868 kka2_1:4_F240V,kka2_1:4_240,Kka2,kka2_1:4,P00552,0.818717,NO,240,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-0.911,-3.287,2.376,,,H,A,0.58,-1.21,5.798,,50.38,BHH,-1.67267,0.168804,0.00552543,0.818717 kka2_1:2_A229Y,kka2_1:2_229,Kka2,kka2_1:2,P00552,0.81876,NO,229,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.739,-4.342,2.603,,0.32,H,A,0.46,-0.7,6.549,,63.64,HHA,-1.851,0.295029,0.00942138,0.81876 beta-lactamase_L10Q,beta-lactamase_10,TEM-1,beta-lactamase,P62593,0.818788,NO,10,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.623,-4.147,2.524,,,,,,,2.467,,65.38,HHH,-1.83833,0.221079,0.00296968,0.818788 PSD95pdz3_I359P,PSD95pdz3_359,PSD95pdz3,PSD95pdz3,P31016,0.818858,NO,359,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.63,-3.786,2.156,5.35151,,,,,14.8012,,,,PHH,-1.58667,0.0758425,0.000580694,0.818858 kka2_1:8_P132K,kka2_1:8_132,Kka2,kka2_1:8,P00552,0.818928,NO,132,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.775,-3.483,2.708,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.100394,0.0018489,0.818928 kka2_1:8_P132K,kka2_1:8_132,Kka2,kka2_1:8,P00552,0.818928,NO,132,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.775,-3.483,2.708,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.100394,0.0018489,0.818928 Pab1_K166S,Pab1_166,Pab1,Pab1,P04147,0.819063,NO,166,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.262,-3.121,1.859,,0.299,,l,,0,,,,PBO,-1.21033,0.175299,0.0011038,0.819063 kka2_1:1_D23N,kka2_1:1_23,Kka2,kka2_1:1,P00552,0.819128,NO,23,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.459,-3.82,1.361,,0.695,E,B,0.75,-0.65,2.655,,65.53,HAH,-1.94033,0.520039,0.007195,0.819128 gb1_V265F,gb1_265,gb1,gb1,P06654,0.819147,NO,265,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.843,-3.914,2.071,,,,,,,0.402,,11.83,OHA,-1.64567,0.177985,0.00360613,0.819147 gb1_V280I,gb1_280,gb1,gb1,P06654,0.819147,NO,280,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.764,-2.845,1.081,,,,,,,0.874,,35.71,PHP,-1.63733,0.177985,0.00321577,0.819147 beta-lactamase_0_T69A,beta-lactamase_0_69,TEM-1,beta-lactamase_0,P62593,0.819274,NO,69,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-0.973,-2.115,1.142,,,G,A,0.22,-1.24,0.505,,93.01,PPH,-1.01833,0.0500837,0.00127498,0.819274 beta-lactamase_39_E35W,beta-lactamase_39_35,TEM-1,beta-lactamase_39,P62593,0.819293,NO,35,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-0.869,-5.371,4.502,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.0495842,0.00174441,0.819293 beta-lactamase_F13H,beta-lactamase_13,TEM-1,beta-lactamase,P62593,0.819327,NO,13,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-2.394,-4.653,2.259,,,,,,,4.079,,77.62,OHH,-2.382,0.221079,0.0029078,0.819327 kka2_1:1_E161A,kka2_1:1_161,Kka2,kka2_1:1,P00552,0.819328,NO,161,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.581,-1.927,0.346,,0.829,G,A,1.04,2.24,1.612,,92.05,AAB,-1.861,0.520039,0.00760103,0.819328 kka2_1:8_C209I,kka2_1:8_209,Kka2,kka2_1:8,P00552,0.819412,NO,209,C,I,CI,Special,Hydrophobic,5.07,6.02,0.95,198,121,131,10,108.5,166.7,58.2,-0.906,-3.519,2.613,,,,a,1.5,-0.89,0.391,,19.32,AOO,-0.903,0.100394,0.00260862,0.819412 kka2_1:8_C209I,kka2_1:8_209,Kka2,kka2_1:8,P00552,0.819412,NO,209,C,I,CI,Special,Hydrophobic,5.07,6.02,0.95,198,121,131,10,108.5,166.7,58.2,-0.906,-3.519,2.613,,,,a,1.5,-0.89,0.391,,19.32,AOO,-0.903,0.100394,0.00260862,0.819412 beta-lactamase_0_S96W,beta-lactamase_0_96,TEM-1,beta-lactamase_0,P62593,0.819426,NO,96,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.27,-5.497,3.227,,0.368,,b,0.27,0.39,2.516,,73.78,HPP,-2.019,0.0500837,0.00551835,0.819426 beta-lactamase_0_R63M,beta-lactamase_0_63,TEM-1,beta-lactamase_0,P62593,0.819427,NO,63,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-0.943,-4.402,3.459,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.0500837,0.00126938,0.819427 beta-lactamase_0_L73F,beta-lactamase_0_73,TEM-1,beta-lactamase_0,P62593,0.819453,NO,73,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.507,-2.19,0.683,,,H,A,0.55,-0.64,0.877,,67.83,HHH,-1.487,0.0500837,0.00488983,0.819453 beta-lactamase_0_D83L,beta-lactamase_0_83,TEM-1,beta-lactamase_0,P62593,0.819458,NO,83,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.066,-3.79,2.724,,0.354,H,A,0.75,0.22,0.617,,48.95,HAH,-1.34733,0.0500837,0.00205968,0.819458 kka2_1:2_I228T,kka2_1:2_228,Kka2,kka2_1:2,P00552,0.819481,NO,228,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.142,-3.482,2.34,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.295029,0.00458834,0.819481 kka2_1:4_C77H,kka2_1:4_77,Kka2,kka2_1:4,P00552,0.819527,NO,77,C,H,CH,Special,PositiveCharge,5.07,7.59,2.52,174,121,155,34,108.5,153.2,44.7,-1.477,-4.937,3.46,,0.229,B,b,0.46,-0.57,2.499,,63.26,OOH,-1.55667,0.168804,0.00441216,0.819527 beta-lactamase_T138P,beta-lactamase_138,TEM-1,beta-lactamase,P62593,0.819616,NO,138,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.506,-3.038,0.532,5.52585,0.662,H,A,0.3,-0.03,30.445,30.445,73.78,HPP,-1.81233,0.221079,0.00487868,0.819616 beta-lactamase_625_I229A,beta-lactamase_625_229,TEM-1,beta-lactamase_625,P62593,0.819671,NO,229,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.267,-3.077,1.81,,0.083,E,B,0.48,-0.76,1.69,,50,HHH,-1.58767,0.213352,0.00477249,0.819671 kka2_1:1_A56Q,kka2_1:1_56,Kka2,kka2_1:1,P00552,0.819723,NO,56,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.083,-4.08,1.997,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.520039,0.00717715,0.819723 beta-lactamase_2500_R41Y,beta-lactamase_2500_41,TEM-1,beta-lactamase_2500,P62593,0.819764,NO,41,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-0.942,-4.188,3.246,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.361275,0.00123327,0.819764 beta-lactamase_G141A,beta-lactamase_141,TEM-1,beta-lactamase,P62593,0.819765,NO,141,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.828,-2.988,2.16,5.03155,0.575,T,l,0.76,-0.28,0.198,,64.69,HOO,-1.08933,0.221079,0.0012419,0.819765 beta-lactamase_2500_R41I,beta-lactamase_2500_41,TEM-1,beta-lactamase_2500,P62593,0.819799,NO,41,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-0.942,-4.008,3.066,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.361275,0.00123327,0.819799 kka2_1:1_Q252H,kka2_1:1_252,Kka2,kka2_1:1,P00552,0.819826,NO,252,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.63,-3.494,0.864,,0.906,H,A,0.64,0.35,1.369,,92.05,PPB,-2.20733,0.520039,0.0121001,0.819826 beta-lactamase_2500_G253P,beta-lactamase_2500_253,TEM-1,beta-lactamase_2500,P62593,0.819849,NO,253,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-2.253,-2.791,0.538,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.361275,0.00786358,0.819849 beta-lactamase_0_D174G,beta-lactamase_0_174,TEM-1,beta-lactamase_0,P62593,0.819863,NO,174,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.738,-3.133,2.395,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.0500837,0.00125633,0.819863 kka2_1:4_A229V,kka2_1:4_229,Kka2,kka2_1:4,P00552,0.819866,NO,229,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.739,-2.471,0.732,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.168804,0.00942138,0.819866 kka2_1:4_P109V,kka2_1:4_109,Kka2,kka2_1:4,P00552,0.81987,NO,109,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.412,-2.937,1.525,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.168804,0.0070929,0.81987 beta-lactamase_2500_E35Q,beta-lactamase_2500_35,TEM-1,beta-lactamase_2500,P62593,0.819878,NO,35,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-0.869,-3.292,2.423,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.361275,0.00174441,0.819878 beta-lactamase_156_G226I,beta-lactamase_156_226,TEM-1,beta-lactamase_156,P62593,0.819882,NO,226,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.461,-4.177,2.716,,0.701,T,l,0.29,-0.25,3.199,,74.48,HOH,-1.42933,0.111618,0.00665294,0.819882 beta-lactamase_0_G240Q,beta-lactamase_0_240,TEM-1,beta-lactamase_0,P62593,0.819902,NO,240,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.0500837,0.00591201,0.819902 beta-lactamase_2500_E119N,beta-lactamase_2500_119,TEM-1,beta-lactamase_2500,P62593,0.819931,NO,119,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.412,-3.591,2.179,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.361275,0.00386966,0.819931 kka2_1:4_R44V,kka2_1:4_44,Kka2,kka2_1:4,P00552,0.819945,NO,44,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.062,-3.733,1.671,,0.487,S,B,1.2,-0.35,5.71,,71.59,OBO,-1.80767,0.168804,0.00745043,0.819945 kka2_1:8_R121Q,kka2_1:8_121,Kka2,kka2_1:8,P00552,0.820006,NO,121,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.552,-2.59,1.038,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.100394,0.00523326,0.820006 kka2_1:8_R121Q,kka2_1:8_121,Kka2,kka2_1:8,P00552,0.820006,NO,121,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.552,-2.59,1.038,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.100394,0.00523326,0.820006 beta-lactamase_0_W288Q,beta-lactamase_0_288,TEM-1,beta-lactamase_0,P62593,0.820015,NO,288,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,,,,,,,,,,,,,BHO,,0.0500837,,0.820015 kka2_1:4_S105Q,kka2_1:4_105,Kka2,kka2_1:4,P00552,0.82004,NO,105,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.945,-3.245,1.3,,0.056,S,B,0.77,-1.04,3.442,,65.53,PPB,-2.17033,0.168804,0.00847233,0.82004 Pab1_N139Y,Pab1_139,Pab1,Pab1,P04147,0.820061,NO,139,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-1.079,-3.98,2.901,,0.062,H,A,,-0.73,,,,APB,-1.09667,0.175299,0.000339145,0.820061 PSD95pdz3_N363P,PSD95pdz3_363,PSD95pdz3,PSD95pdz3,P31016,0.820067,NO,363,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-1.41,-3.561,2.151,5.23349,,,,,20.7037,,,,HPO,-1.29433,0.0758425,0.000524014,0.820067 beta-lactamase_P224E,beta-lactamase_224,TEM-1,beta-lactamase,P62593,0.820092,NO,224,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.893,-3.439,2.546,5.179,0.383,,B,0.99,-0.3,0.383,,74.48,HOH,-1.26433,0.221079,0.00189564,0.820092 beta-lactamase_L55S,beta-lactamase_55,TEM-1,beta-lactamase,P62593,0.820101,NO,55,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.86,-3.706,1.846,,0.372,E,A,1.07,-0.36,1.423,,63.99,HHA,-2.247,0.221079,0.00403741,0.820101 beta-lactamase_2500_I229M,beta-lactamase_2500_229,TEM-1,beta-lactamase_2500,P62593,0.820128,NO,229,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.267,-4.125,2.858,,0.083,E,B,0.48,-0.76,3.875,,50,HHH,-1.58767,0.361275,0.00477249,0.820128 gb1_Y259K,gb1_259,gb1,gb1,P06654,0.820134,NO,259,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-1.78,-3.682,1.902,,,,,,,0.131,,11.83,PHH,-1.787,0.177985,0.00464313,0.820134 beta-lactamase_2500_T147E,beta-lactamase_2500_147,TEM-1,beta-lactamase_2500,P62593,0.820201,NO,147,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.149,-3.519,2.37,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.361275,0.00226017,0.820201 beta-lactamase_39_W288A,beta-lactamase_39_288,TEM-1,beta-lactamase_39,P62593,0.820221,NO,288,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,,,,,,,,,,,,,BHO,,0.0495842,,0.820221 beta-lactamase_2500_T198L,beta-lactamase_2500_198,TEM-1,beta-lactamase_2500,P62593,0.820265,NO,198,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.168,-3.433,1.265,,0.489,,B,0.22,-0.13,0.37,,73.78,HPH,-1.98767,0.361275,0.004311,0.820265 beta-lactamase_A211A,beta-lactamase_211,TEM-1,beta-lactamase,P62593,0.82037,NO,211,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.896,-1.896,,5.54662,0.369,T,A,0.52,-0.69,2.061,,77.62,AHA,-1.94633,0.221079,0.00648183,0.82037 beta-lactamase_R7C,beta-lactamase_7,TEM-1,beta-lactamase,P62593,0.82037,NO,7,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.683,-2.796,1.113,,,,,,,2.44,,67.13,HBH,-1.96267,0.221079,0.00211375,0.82037 beta-lactamase_P65A,beta-lactamase_65,TEM-1,beta-lactamase,P62593,0.820411,NO,65,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.894,-3.096,2.202,5.59094,0.098,E,B,0.23,-0.62,0.623,,40.56,HOH,-1.03233,0.221079,0.00152776,0.820411 beta-lactamase_0_L47A,beta-lactamase_0_47,TEM-1,beta-lactamase_0,P62593,0.82044,NO,47,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.876,-3.301,1.425,,0.007,E,B,0.55,0.2,1.024,,67.83,AHA,-1.639,0.0500837,0.00439844,0.82044 beta-lactamase_P165G,beta-lactamase_165,TEM-1,beta-lactamase,P62593,0.820465,NO,165,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.373,-3.429,2.056,5.33889,0.203,T,A,0.99,-0.31,0.414,,73.78,AOA,-1.359,0.221079,0.00549538,0.820465 beta-lactamase_0_V101F,beta-lactamase_0_101,TEM-1,beta-lactamase_0,P62593,0.820474,NO,101,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.295,-3.936,2.641,,0.342,,B,0.44,0,1.61,,73.08,HHA,-1.54367,0.0500837,0.00374492,0.820474 gb1_V280L,gb1_280,gb1,gb1,P06654,0.820626,NO,280,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.764,-1.937,0.173,,,,,,,0.874,,35.71,PHP,-1.63733,0.177985,0.00321577,0.820626 beta-lactamase_0_R159C,beta-lactamase_0_159,TEM-1,beta-lactamase_0,P62593,0.820646,NO,159,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-0.94,-5.113,4.173,,0.316,,B,1.2,-0.55,1.426,,64.34,PBH,-1.011,0.0500837,0.00108472,0.820646 kka2_1:8_G201H,kka2_1:8_201,Kka2,kka2_1:8,P00552,0.820691,NO,201,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.56,-3.46,1.9,,0.149,T,l,0.75,-0.57,2.152,,52.65,POB,-1.92233,0.100394,0.00820117,0.820691 kka2_1:8_G201H,kka2_1:8_201,Kka2,kka2_1:8,P00552,0.820691,NO,201,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.56,-3.46,1.9,,0.149,T,l,0.75,-0.57,2.152,,52.65,POB,-1.92233,0.100394,0.00820117,0.820691 beta-lactamase_0_L49E,beta-lactamase_0_49,TEM-1,beta-lactamase_0,P62593,0.820746,NO,49,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.897,-3.608,1.711,,0.131,T,A,0.55,0.04,13.838,13.838,64.69,AHP,-1.99233,0.0500837,0.00401477,0.820746 beta-lactamase_2500_S51H,beta-lactamase_2500_51,TEM-1,beta-lactamase_2500,P62593,0.820753,NO,51,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.526,-4.622,3.096,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.361275,0.00504821,0.820753 beta-lactamase_0_D83Q,beta-lactamase_0_83,TEM-1,beta-lactamase_0,P62593,0.820774,NO,83,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.066,-3.681,2.615,,0.354,H,A,0.75,0.22,0.617,,48.95,HAH,-1.34733,0.0500837,0.00205968,0.820774 beta-lactamase_0_S221L,beta-lactamase_0_221,TEM-1,beta-lactamase_0,P62593,0.820774,NO,221,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.754,-3.35,1.596,,0.624,H,A,0.27,-0.2,2.914,,74.48,BPH,-1.59967,0.0500837,0.0046094,0.820774 beta-lactamase_2500_W163P,beta-lactamase_2500_163,TEM-1,beta-lactamase_2500,P62593,0.820853,NO,163,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-1.843,-4.201,2.358,,0.467,,B,0.47,-0.5,32.624,32.624,63.99,BHA,-1.269,0.361275,0.00418955,0.820853 kka2_1:4_T125I,kka2_1:4_125,Kka2,kka2_1:4,P00552,0.820905,NO,125,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.622,-3.99,1.368,,0.791,T,A,0.82,0.33,1.612,,92.05,BPH,-1.56933,0.168804,0.00821755,0.820905 kka2_1:1_A25H,kka2_1:1_25,Kka2,kka2_1:1,P00552,0.82095,NO,25,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.496,-3.145,0.649,,0.427,E,B,0.46,-0.47,6.872,6.872,65.53,HHP,-2.15167,0.520039,0.00595636,0.82095 beta-lactamase_39_G249Q,beta-lactamase_39_249,TEM-1,beta-lactamase_39,P62593,0.821025,NO,249,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.312,,,,0.256,S,B,0.23,0.04,30.841,30.841,72.73,HOO,-1.81367,0.0495842,0.00220169,0.821025 beta-lactamase_0_E175K,beta-lactamase_0_175,TEM-1,beta-lactamase_0,P62593,0.821044,NO,175,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.336,-2.673,0.337,,0.551,,A,1.04,1.05,2.334,,77.62,AAB,-1.31233,0.0500837,0.00482205,0.821044 kka2_1:2_T225F,kka2_1:2_225,Kka2,kka2_1:2,P00552,0.821047,NO,225,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.393,-4.221,1.828,,0.036,H,A,0.22,-1.22,4.554,,63.64,HPB,-1.58733,0.295029,0.0113598,0.821047 beta-lactamase_L197F,beta-lactamase_197,TEM-1,beta-lactamase,P62593,0.82105,NO,197,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.853,-3.685,2.832,5.19172,0.007,S,B,1.3,0.33,1.756,,60.14,HHP,-1.833,0.221079,0.00144602,0.82105 beta-lactamase_0_P165E,beta-lactamase_0_165,TEM-1,beta-lactamase_0,P62593,0.821106,NO,165,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.373,-3.511,2.138,,0.203,T,A,0.52,-0.31,3.242,,73.78,AOA,-1.359,0.0500837,0.00549538,0.821106 gb1_T237D,gb1_237,gb1,gb1,P06654,0.821115,NO,237,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.736,-3.158,1.422,,,,,,,0.218,,11.83,BPH,-2.27833,0.177985,0.00275316,0.821115 Pab1_Y143T,Pab1_143,Pab1,Pab1,P04147,0.821144,NO,143,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-1.961,-3.578,1.617,,0.409,H,A,,0.3,,,,HHA,-1.39633,0.175299,0.00160364,0.821144 beta-lactamase_2500_A222F,beta-lactamase_2500_222,TEM-1,beta-lactamase_2500,P62593,0.821155,NO,222,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.103,-4.23,2.127,,0.233,H,A,0.46,-0.25,0.379,,77.62,PHH,-1.63733,0.361275,0.00466094,0.821155 kka2_1:4_V97L,kka2_1:4_97,Kka2,kka2_1:4,P00552,0.821188,NO,97,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.453,-1.404,-0.049,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.168804,0.00737869,0.821188 kka2_1:1_L92P,kka2_1:1_92,Kka2,kka2_1:1,P00552,0.821348,NO,92,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.893,-4.134,3.241,,0.007,E,B,0.55,-0.19,1.447,,63.26,HHH,-0.962,0.520039,0.00307177,0.821348 beta-lactamase_0_V29I,beta-lactamase_0_29,TEM-1,beta-lactamase_0,P62593,0.821447,NO,29,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-2.856,-3.928,1.072,,0.733,H,A,0.44,-0.78,21.916,21.916,93.01,HHB,-2.24733,0.0500837,0.00318969,0.821447 kka2_1:1_Q163V,kka2_1:1_163,Kka2,kka2_1:1,P00552,0.821458,NO,163,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.162,-2.687,0.525,,0.58,T,B,0.64,1.85,2.779,,64.02,BPO,-1.78333,0.520039,0.00719507,0.821458 beta-lactamase_0_G142C,beta-lactamase_0_142,TEM-1,beta-lactamase_0,P62593,0.821489,NO,142,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.707,-5.05,4.343,,0.034,,p,0.29,-0.64,1.947,,64.69,OOO,-0.834,0.0500837,0.00060149,0.821489 beta-lactamase_A246G,beta-lactamase_246,TEM-1,beta-lactamase,P62593,0.821514,NO,246,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.121,-3.675,1.554,4.78979,0.01,E,B,0.52,-1.01,1.26,,73.78,HHH,-1.55633,0.221079,0.00569458,0.821514 beta-lactamase_2500_A278L,beta-lactamase_2500_278,TEM-1,beta-lactamase_2500,P62593,0.821559,NO,278,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.361275,0.0310297,0.821559 beta-lactamase_T27A,beta-lactamase_27,TEM-1,beta-lactamase,P62593,0.821561,NO,27,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.905,-2.5,0.595,5.39752,0.007,H,A,0.69,-0.37,0.745,,93.01,APH,-1.97933,0.221079,0.00306559,0.821561 beta-lactamase_I93C,beta-lactamase_93,TEM-1,beta-lactamase,P62593,0.821574,NO,93,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.401,-4.797,3.396,5.74695,0.128,E,B,0.77,0.44,1.757,,67.83,BHB,-1.873,0.221079,0.00527066,0.821574 kka2_1:4_L57A,kka2_1:4_57,Kka2,kka2_1:4,P00552,0.82162,NO,57,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.898,-3.394,1.496,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.168804,0.00723769,0.82162 beta-lactamase_P12E,beta-lactamase_12,TEM-1,beta-lactamase,P62593,0.821635,NO,12,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-2.016,-3.594,1.578,,,,,,,2.88,,72.73,HOH,-2.05167,0.221079,0.00241653,0.821635 kka2_1:1_Q155K,kka2_1:1_155,Kka2,kka2_1:1,P00552,0.821721,NO,155,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.606,-3.316,0.71,,0.525,T,A,0.4,1.49,4.415,,63.64,APA,-1.726,0.520039,0.00641853,0.821721 beta-lactamase_0_D177G,beta-lactamase_0_177,TEM-1,beta-lactamase_0,P62593,0.821826,NO,177,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.967,-2.392,1.425,,0.006,T,L,0.75,-1.02,3.536,,64.69,BAP,-0.873667,0.0500837,0.000864022,0.821826 kka2_1:4_A110P,kka2_1:4_110,Kka2,kka2_1:4,P00552,0.821831,NO,110,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.064,-3.089,1.025,,0.175,H,A,0.46,-1.19,23.237,23.237,71.59,OHA,-1.91867,0.168804,0.00759851,0.821831 beta-lactamase_L89W,beta-lactamase_89,TEM-1,beta-lactamase,P62593,0.821896,NO,89,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.096,-5.236,4.14,5.41092,0.168,T,A,1.75,0.63,1.599,,64.34,PHO,-1.75767,0.221079,0.00207068,0.821896 kka2_1:2_E161M,kka2_1:2_161,Kka2,kka2_1:2,P00552,0.822014,NO,161,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.581,-4.788,3.207,,0.829,G,A,1.52,2.24,1.612,,92.05,AAB,-1.861,0.295029,0.00760103,0.822014 beta-lactamase_2500_M270T,beta-lactamase_2500_270,TEM-1,beta-lactamase_2500,P62593,0.822072,NO,270,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.723,,,,0.422,H,A,1.59,1.15,2.029,,64.34,PHA,-1.70933,0.361275,0.00767762,0.822072 PSD95pdz3_R312W,PSD95pdz3_312,PSD95pdz3,PSD95pdz3,P31016,0.822099,NO,312,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.582,-5.004,3.422,5.76826,,,,,12.2409,,,,OBB,-1.46667,0.0758425,0.00196255,0.822099 kka2_1:4_H135Q,kka2_1:4_135,Kka2,kka2_1:4,P00552,0.822188,NO,135,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-1.331,-2.136,0.805,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.168804,0.00532566,0.822188 beta-lactamase_0_E35W,beta-lactamase_0_35,TEM-1,beta-lactamase_0,P62593,0.822205,NO,35,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-0.869,-5.371,4.502,,0.15,H,A,1.04,0.21,0.664,,46.85,HAA,-1.88667,0.0500837,0.00174441,0.822205 kka2_1:1_G43S,kka2_1:1_43,Kka2,kka2_1:1,P00552,0.822208,NO,43,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.587,-2.69,1.103,,0.862,T,l,0.75,-0.67,2.247,,63.26,POB,-2.18533,0.520039,0.0071925,0.822208 kka2_1:8_Y244V,kka2_1:8_244,Kka2,kka2_1:8,P00552,0.822265,NO,244,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-0.775,-3.332,2.557,,0.066,H,A,1.25,-0.64,,,,HHO,-1.41267,0.100394,0.00453187,0.822265 kka2_1:8_Y244V,kka2_1:8_244,Kka2,kka2_1:8,P00552,0.822265,NO,244,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-0.775,-3.332,2.557,,0.066,H,A,1.25,-0.64,,,,HHO,-1.41267,0.100394,0.00453187,0.822265 kka2_1:4_L102I,kka2_1:4_102,Kka2,kka2_1:4,P00552,0.822328,NO,102,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.804,-2.957,2.153,,,T,A,0.55,-1.17,0.65,,42.42,AHH,-1.398,0.168804,0.00201332,0.822328 beta-lactamase_D174C,beta-lactamase_174,TEM-1,beta-lactamase,P62593,0.82236,NO,174,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.738,-5.087,4.349,5.44133,0.238,,B,1.22,-0.1,,,,PAA,-1.91233,0.221079,0.00125633,0.82236 beta-lactamase_0_K53S,beta-lactamase_0_53,TEM-1,beta-lactamase_0,P62593,0.822424,NO,53,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-2.313,-2.879,0.566,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.0500837,0.00383383,0.822424 kka2_1:8_G210T,kka2_1:8_210,Kka2,kka2_1:8,P00552,0.822445,NO,210,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.095,-3.513,2.418,,0.103,T,A,0.75,-0.62,2.687,,50,OOB,-0.966667,0.100394,0.00598378,0.822445 kka2_1:8_G210T,kka2_1:8_210,Kka2,kka2_1:8,P00552,0.822445,NO,210,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.095,-3.513,2.418,,0.103,T,A,0.75,-0.62,2.687,,50,OOB,-0.966667,0.100394,0.00598378,0.822445 kka2_1:1_V97R,kka2_1:1_97,Kka2,kka2_1:1,P00552,0.822468,NO,97,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.453,-4.167,2.714,,0.083,,B,1.48,-0.83,13.576,13.576,53.03,AHO,-1.85067,0.520039,0.00737869,0.822468 beta-lactamase_0_R91W,beta-lactamase_0_91,TEM-1,beta-lactamase_0,P62593,0.822472,NO,91,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.392,-5.388,3.996,,0.444,,B,1.2,0.96,4.557,,50.35,OBB,-1.73367,0.0500837,0.00380226,0.822472 kka2_1:4_R140T,kka2_1:4_140,Kka2,kka2_1:4,P00552,0.822508,NO,140,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.351,-2.806,1.455,,0.12,H,A,1.2,0.2,2.561,,53.03,BBH,-1.885,0.168804,0.00430167,0.822508 gb1_A246I,gb1_246,gb1,gb1,P06654,0.822576,NO,246,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.175,-3.296,2.121,,,,,,,,,,AHH,-1.87033,0.177985,0.00190625,0.822576 gb1_L238V,gb1_238,gb1,gb1,P06654,0.822576,NO,238,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-2.98,-3.266,0.286,,,,,,,0.504,,45.54,PHB,-2.58633,0.177985,0.00205885,0.822576 Ubiquitin_D32F,Ubiquitin_32,Uba1,Ubiquitin,P0CG48,0.822581,NO,32,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.451,-4.158,2.707,4.96502,0.835,H,A,,1.4,,,,PAB,-1.47067,0.205827,0.000758819,0.822581 Ubiquitin_D32L,Ubiquitin_32,Uba1,Ubiquitin,P0CG48,0.822581,NO,32,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.451,-3.614,2.163,4.96502,0.835,H,A,,1.4,,,,PAB,-1.47067,0.205827,0.000758819,0.822581 Ubiquitin_G47A,Ubiquitin_47,Uba1,Ubiquitin,P0CG48,0.822581,NO,47,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.423,-3.066,1.643,5.24944,0.057,T,l,,-1.21,,,,HOB,-1.543,0.205827,0.000471587,0.822581 Ubiquitin_H68A,Ubiquitin_68,Uba1,Ubiquitin,P0CG48,0.822581,NO,68,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-1.869,-2.742,0.873,4.81902,0.194,E,B,0.72,-1.02,21.325,21.325,65.11,HBH,-1.583,0.205827,0.000925438,0.822581 Ubiquitin_I23R,Ubiquitin_23,Uba1,Ubiquitin,P0CG48,0.822581,NO,23,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.325,-4.129,2.804,4.67534,,H,A,0.01,-0.93,0.515,,52.12,PHA,-1.54033,0.205827,0.000621252,0.822581 Ubiquitin_I36Q,Ubiquitin_36,Uba1,Ubiquitin,P0CG48,0.822581,NO,36,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.477,-4.141,2.664,5.1035,0.203,,B,0.27,-0.22,1.552,,30.8,OHO,-1.30767,0.205827,0.000630555,0.822581 Ubiquitin_L15E,Ubiquitin_15,Uba1,Ubiquitin,P0CG48,0.822581,NO,15,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.082,-3.873,2.791,5.14718,0.029,E,B,1.16,-0.53,0.936,,38.69,PHA,-1.40833,0.205827,0.000519738,0.822581 Ubiquitin_Q40F,Ubiquitin_40,Uba1,Ubiquitin,P0CG48,0.822581,NO,40,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-1.752,-4.183,2.431,4.7807,0.387,G,A,,0.03,,,,APP,-1.62433,0.205827,0.000619089,0.822581 Ubiquitin_Q41T,Ubiquitin_41,Uba1,Ubiquitin,P0CG48,0.822581,NO,41,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-1.329,-3.523,2.194,4.9201,0.017,E,B,0.12,-0.98,0.812,,30.07,PPB,-1.55067,0.205827,0.000521668,0.822581 Ubiquitin_T9P,Ubiquitin_9,Uba1,Ubiquitin,P0CG48,0.822581,NO,9,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.409,-3.82,2.411,5.24336,0.777,T,A,2.12,-0.12,2.705,,29.93,HPO,-1.50933,0.205827,0.000630716,0.822581 beta-lactamase_0_G114L,beta-lactamase_0_114,TEM-1,beta-lactamase_0,P62593,0.822636,NO,114,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.094,-3.637,2.543,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.0500837,0.00224919,0.822636 beta-lactamase_0_S266V,beta-lactamase_0_266,TEM-1,beta-lactamase_0,P62593,0.822686,NO,266,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.0500837,0.0140785,0.822686 beta-lactamase_A16K,beta-lactamase_16,TEM-1,beta-lactamase,P62593,0.822697,NO,16,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,,-3.608,1.673,,,,,,,,,,HHH,,0.221079,0.00245392,0.822697 beta-lactamase_C18F,beta-lactamase_18,TEM-1,beta-lactamase,P62593,0.822697,NO,18,C,F,CF,Special,Hydrophobic,5.07,3.32051,-1.74949,205,121,165,44,108.5,189.9,81.4,-2.26,-4.176,1.916,,,,,,,3.995,,93.01,HOH,-2.093,0.221079,0.002536,0.822697 beta-lactamase_E26E,beta-lactamase_26,TEM-1,beta-lactamase,P62593,0.822697,NO,26,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.454,-2.454,,,0.54,H,A,1.04,0.98,,,93.01,OAP,-1.96167,0.221079,0.00297948,0.822697 beta-lactamase_G142S,beta-lactamase_142,TEM-1,beta-lactamase,P62593,0.822697,NO,142,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.707,-2.438,1.731,4.55474,0.034,,p,0.77,-0.64,1.947,,64.69,OOO,-0.834,0.221079,0.00060149,0.822697 beta-lactamase_R159D,beta-lactamase_159,TEM-1,beta-lactamase,P62593,0.822697,NO,159,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-0.94,-3.691,2.751,5.64971,0.316,,B,0.68,-0.55,1.172,,64.34,PBH,-1.011,0.221079,0.00108472,0.822697 beta-lactamase_R59Q,beta-lactamase_59,TEM-1,beta-lactamase,P62593,0.822697,NO,59,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.345,-2.612,1.267,5.49837,0.329,S,L,0.68,-0.09,1.806,,73.08,HBO,-2.24267,0.221079,0.00318082,0.822697 beta-lactamase_T261Y,beta-lactamase_261,TEM-1,beta-lactamase,P62593,0.822697,NO,261,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.88,-3.135,0.255,5.65483,0.014,E,B,0.53,-0.39,2.449,,77.62,HPP,-1.771,0.221079,0.0123091,0.822697 kka2_1:2_Q136H,kka2_1:2_136,Kka2,kka2_1:2,P00552,0.822731,NO,136,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-3.021,-3.255,0.234,,0.331,,b,0.4,0.96,2.726,,92.05,BPH,-2.16933,0.295029,0.00624149,0.822731 beta-lactamase_2500_R91T,beta-lactamase_2500_91,TEM-1,beta-lactamase_2500,P62593,0.822736,NO,91,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.392,-2.721,1.329,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.361275,0.00380226,0.822736 beta-lactamase_0_G52C,beta-lactamase_0_52,TEM-1,beta-lactamase_0,P62593,0.822794,NO,52,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.149,-5.084,3.935,,0.299,,l,0.29,-0.04,1.164,,64.69,POB,-1.66267,0.0500837,0.00340138,0.822794 beta-lactamase_0_L248M,beta-lactamase_0_248,TEM-1,beta-lactamase_0,P62593,0.822802,NO,248,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.0500837,0.00428493,0.822802 beta-lactamase_0_A235H,beta-lactamase_0_235,TEM-1,beta-lactamase_0,P62593,0.822813,NO,235,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.266,-4.769,3.503,,0.32,E,B,0.46,-0.86,2.261,,50,OHO,-0.89,0.0500837,0.00493474,0.822813 beta-lactamase_L135C,beta-lactamase_135,TEM-1,beta-lactamase,P62593,0.822945,NO,135,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.002,-4.691,3.689,5.28497,0.117,H,A,1.07,-0.58,0.697,,43.71,PHH,-1.03767,0.221079,0.00244423,0.822945 beta-lactamase_0_L197Y,beta-lactamase_0_197,TEM-1,beta-lactamase_0,P62593,0.822979,NO,197,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.853,-3.986,3.133,,0.007,S,B,0.55,0.33,1.087,,60.14,HHP,-1.833,0.0500837,0.00144602,0.822979 kka2_1:2_E149A,kka2_1:2_149,Kka2,kka2_1:2,P00552,0.823025,NO,149,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.994,-2.44,0.446,,0.674,H,A,1.04,1.63,15.361,15.361,71.59,HAH,-1.59667,0.295029,0.00803343,0.823025 beta-lactamase_0_G236K,beta-lactamase_0_236,TEM-1,beta-lactamase_0,P62593,0.82303,NO,236,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.784,-3.651,2.867,,0.241,,b,0.29,-0.59,3.506,,64.69,HOO,-1.025,0.0500837,0.00162372,0.82303 beta-lactamase_0_T69S,beta-lactamase_0_69,TEM-1,beta-lactamase_0,P62593,0.823062,NO,69,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-0.973,-2.405,1.432,,,G,A,0.22,-1.24,0.505,,93.01,PPH,-1.01833,0.0500837,0.00127498,0.823062 beta-lactamase_R92D,beta-lactamase_92,TEM-1,beta-lactamase,P62593,0.823076,NO,92,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.718,-3.708,1.99,5.65832,0.479,E,B,0.91,1.36,3.069,,65.38,BBH,-1.50367,0.221079,0.00429626,0.823076 beta-lactamase_0_A183D,beta-lactamase_0_183,TEM-1,beta-lactamase_0,P62593,0.823085,NO,183,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.231,-2.686,1.455,,0.155,H,A,0.46,-0.91,1.48,,77.62,HHH,-1.53367,0.0500837,0.00296631,0.823085 beta-lactamase_P165E,beta-lactamase_165,TEM-1,beta-lactamase,P62593,0.823223,NO,165,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.373,-3.511,2.138,5.33889,0.203,T,A,0.99,-0.31,0.414,,73.78,AOA,-1.359,0.221079,0.00549538,0.823223 Pab1_L186G,Pab1_186,Pab1,Pab1,P04147,0.823245,NO,186,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.783,-3.654,1.871,,,,,,,,,,HHP,-1.56967,0.175299,0.00154968,0.823245 kka2_1:8_V36C,kka2_1:8_36,Kka2,kka2_1:8,P00552,0.823375,NO,36,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-0.898,-4.71,3.812,,0.292,E,B,1.48,0.21,0.938,,52.27,HHH,-1.484,0.100394,0.00245633,0.823375 kka2_1:8_V36C,kka2_1:8_36,Kka2,kka2_1:8,P00552,0.823375,NO,36,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-0.898,-4.71,3.812,,0.292,E,B,1.48,0.21,0.938,,52.27,HHH,-1.484,0.100394,0.00245633,0.823375 beta-lactamase_0_I171P,beta-lactamase_0_171,TEM-1,beta-lactamase_0,P62593,0.82344,NO,171,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-2.431,-4.052,1.621,,0.361,,B,0.48,0.53,16.954,16.954,77.62,HHO,-1.55533,0.0500837,0.00623355,0.82344 kka2_1:4_I115C,kka2_1:4_115,Kka2,kka2_1:4,P00552,0.82344,NO,115,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.606,-4.846,3.24,,0.105,H,A,1.52,-1.18,9.996,9.996,65.53,PHH,-2.205,0.168804,0.00836567,0.82344 beta-lactamase_0_A185L,beta-lactamase_0_185,TEM-1,beta-lactamase_0,P62593,0.823449,NO,185,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.406,-2.064,0.658,,,H,A,0.46,-1.02,1.203,,65.03,HHP,-1.84033,0.0500837,0.00467449,0.823449 beta-lactamase_G236N,beta-lactamase_236,TEM-1,beta-lactamase,P62593,0.823526,NO,236,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.784,-3.509,2.725,4.7915,0.241,,b,0.23,-0.59,1.883,,64.69,HOA,-1.36933,0.221079,0.00162372,0.823526 kka2_1:4_S32R,kka2_1:4_32,Kka2,kka2_1:4,P00552,0.823537,NO,32,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-0.804,-3.736,2.932,,0.768,S,b,0.27,3.75,,,,OPA,-1.74533,0.168804,0.00149998,0.823537 kka2_1:8_L94E,kka2_1:8_94,Kka2,kka2_1:8,P00552,0.82361,NO,94,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.618,-3.883,2.265,,0.058,E,B,1.59,-0.52,2.197,,56.06,HHO,-1.612,0.100394,0.00520888,0.82361 kka2_1:8_L94E,kka2_1:8_94,Kka2,kka2_1:8,P00552,0.82361,NO,94,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.618,-3.883,2.265,,0.058,E,B,1.59,-0.52,2.197,,56.06,HHO,-1.612,0.100394,0.00520888,0.82361 beta-lactamase_0_R220T,beta-lactamase_0_220,TEM-1,beta-lactamase_0,P62593,0.82363,NO,220,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-0.942,-3.419,2.477,,0.295,I,A,1.2,-0.76,21.573,21.573,74.48,HBP,-1.33633,0.0500837,0.00232421,0.82363 kka2_1:4_E59G,kka2_1:4_59,Kka2,kka2_1:4,P00552,0.823647,NO,59,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-0.952,-3.43,2.478,,0.187,.,L,1.04,0.62,3.408,,50.38,PAH,-1.53,0.168804,0.00280355,0.823647 beta-lactamase_2500_V101C,beta-lactamase_2500_101,TEM-1,beta-lactamase_2500,P62593,0.82371,NO,101,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.295,-4.837,3.542,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.361275,0.00374492,0.82371 PSD95pdz3_I336H,PSD95pdz3_336,PSD95pdz3,PSD95pdz3,P31016,0.823756,NO,336,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.63,-4.587,2.957,5.11321,,,,,13.6363,,,,OHH,-1.38733,0.0758425,0.000887923,0.823756 kka2_1:4_G164C,kka2_1:4_164,Kka2,kka2_1:4,P00552,0.823757,NO,164,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.869,-5.135,4.266,,0.862,T,l,0.75,1.45,1.539,,64.39,POH,-1.828,0.168804,0.00442091,0.823757 beta-lactamase_0_G85R,beta-lactamase_0_85,TEM-1,beta-lactamase_0,P62593,0.823784,NO,85,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.011,-2.784,1.773,,0.805,T,l,0.29,1.7,2.25,,63.64,HOP,-1.68733,0.0500837,0.00252173,0.823784 kka2_1:1_A9L,kka2_1:1_9,Kka2,kka2_1:1,P00552,0.823813,NO,9,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.079,-2.291,0.212,,,,,,,0.383,,71.59,BHO,-2.253,0.520039,0.00273264,0.823813 WW_domain_K181Y,WW_domain_181,Yap65,WW_domain,P46937,0.823822,NO,181,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.35,-3.536,2.186,5.0864,,,,,,0.176,,15.87,HBP,-1.247,0.153962,0.0033022,0.823822 beta-lactamase_0_A185R,beta-lactamase_0_185,TEM-1,beta-lactamase_0,P62593,0.823829,NO,185,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.406,-3.963,2.557,,,H,A,0.46,-1.02,1.203,,65.03,HHP,-1.84033,0.0500837,0.00467449,0.823829 kka2_1:4_N58D,kka2_1:4_58,Kka2,kka2_1:4,P00552,0.823829,NO,58,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-2.641,-2.6,-0.041,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.168804,0.00793425,0.823829 beta-lactamase_2500_L219M,beta-lactamase_2500_219,TEM-1,beta-lactamase_2500,P62593,0.823872,NO,219,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.313,-3.006,1.693,,,I,A,0.55,-0.51,35.994,35.994,74.48,HHB,-1.21533,0.361275,0.00664345,0.823872 beta-lactamase_V31T,beta-lactamase_31,TEM-1,beta-lactamase,P62593,0.823919,NO,31,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.822,-2.805,0.983,5.43781,,H,A,2.78,-0.46,2.885,,73.78,BHB,-2.03767,0.221079,0.00478065,0.823919 beta-lactamase_0_P181E,beta-lactamase_0_181,TEM-1,beta-lactamase_0,P62593,0.823922,NO,181,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.813,-3.466,2.653,,,H,A,0.52,-1.14,1.357,,61.54,HOH,-1.795,0.0500837,0.000703122,0.823922 beta-lactamase_0_E26Y,beta-lactamase_0_26,TEM-1,beta-lactamase_0,P62593,0.823993,NO,26,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.454,-4.272,1.818,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.0500837,0.00297948,0.823993 beta-lactamase_39_G236L,beta-lactamase_39_236,TEM-1,beta-lactamase_39,P62593,0.824005,NO,236,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.784,-3.712,2.928,,0.241,,b,0.29,-0.59,1.883,,64.69,HOO,-1.025,0.0495842,0.00162372,0.824005 beta-lactamase_A211I,beta-lactamase_211,TEM-1,beta-lactamase,P62593,0.824018,NO,211,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.896,-4.033,2.137,5.54662,0.369,T,A,0.52,-0.69,2.061,,77.62,AHA,-1.94633,0.221079,0.00648183,0.824018 beta-lactamase_T116K,beta-lactamase_116,TEM-1,beta-lactamase,P62593,0.824018,NO,116,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.28,-3.42,2.14,4.78335,0.115,E,B,0.69,-0.12,0.343,,67.48,HPH,-1.39967,0.221079,0.00336175,0.824018 beta-lactamase_2500_K32F,beta-lactamase_2500_32,TEM-1,beta-lactamase_2500,P62593,0.824039,NO,32,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.984,-4.328,2.344,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.361275,0.00401283,0.824039 Pab1_K166I,Pab1_166,Pab1,Pab1,P04147,0.824041,NO,166,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.262,-3.903,2.641,,0.299,,l,,0,,,,PBO,-1.21033,0.175299,0.0011038,0.824041 beta-lactamase_0_G240W,beta-lactamase_0_240,TEM-1,beta-lactamase_0,P62593,0.824192,NO,240,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.0500837,0.00591201,0.824192 kka2_1:4_L259T,kka2_1:4_259,Kka2,kka2_1:4,P00552,0.824212,NO,259,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.088,-2.444,1.356,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.168804,0.0206964,0.824212 beta-lactamase_0_E35D,beta-lactamase_0_35,TEM-1,beta-lactamase_0,P62593,0.824222,NO,35,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-0.869,-2.219,1.35,,0.15,H,A,1.04,0.21,0.664,,46.85,HAA,-1.88667,0.0500837,0.00174441,0.824222 kka2_1:8_G205A,kka2_1:8_205,Kka2,kka2_1:8,P00552,0.824274,NO,205,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.596,-2.881,2.285,,,E,b,0.75,-1.05,,,,POH,-1.09933,0.100394,0.00221855,0.824274 kka2_1:8_G205A,kka2_1:8_205,Kka2,kka2_1:8,P00552,0.824274,NO,205,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.596,-2.881,2.285,,,E,b,0.75,-1.05,,,,POH,-1.09933,0.100394,0.00221855,0.824274 kka2_1:2_E86Y,kka2_1:2_86,Kka2,kka2_1:2,P00552,0.824276,NO,86,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.86,-2.948,1.088,,0.369,.,B,1.04,1.92,3.573,,63.26,PAH,-1.98067,0.295029,0.00642858,0.824276 WW_domain_R187C,WW_domain_187,Yap65,WW_domain,P46937,0.824312,NO,187,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.402,-4.927,3.525,5.05189,,,,,,3.431,,78.57,PBH,-1.362,0.153962,0.00171149,0.824312 beta-lactamase_2500_S104A,beta-lactamase_2500_104,TEM-1,beta-lactamase_2500,P62593,0.824324,NO,104,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.015,-2.043,1.028,,0.04,,b,0.27,0.57,1.133,,63.29,HPO,-1.05267,0.361275,0.00218083,0.824324 kka2_1:8_L57V,kka2_1:8_57,Kka2,kka2_1:8,P00552,0.82433,NO,57,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.898,-2.47,0.572,,0.343,T,A,0.55,0.98,13.359,13.359,52.65,HHP,-2.20733,0.100394,0.00723769,0.82433 kka2_1:8_L57V,kka2_1:8_57,Kka2,kka2_1:8,P00552,0.82433,NO,57,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.898,-2.47,0.572,,0.343,T,A,0.55,0.98,13.359,13.359,52.65,HHP,-2.20733,0.100394,0.00723769,0.82433 kka2_1:8_P128C,kka2_1:8_128,Kka2,kka2_1:8,P00552,0.824331,NO,128,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.922,-4.968,3.046,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.100394,0.00774689,0.824331 kka2_1:8_P128C,kka2_1:8_128,Kka2,kka2_1:8,P00552,0.824331,NO,128,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.922,-4.968,3.046,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.100394,0.00774689,0.824331 PSD95pdz3_E373I,PSD95pdz3_373,PSD95pdz3,PSD95pdz3,P31016,0.824361,NO,373,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.404,-3.692,2.288,5.79743,,,,,27.9833,,,,BAP,-1.57667,0.0758425,0.000387698,0.824361 beta-lactamase_39_S122M,beta-lactamase_39_122,TEM-1,beta-lactamase_39,P62593,0.82437,NO,122,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.406,-4.704,2.298,,0.352,H,A,0.27,-0.54,2.004,,77.62,OPH,-1.39767,0.0495842,0.00497825,0.82437 kka2_1:1_E59L,kka2_1:1_59,Kka2,kka2_1:1,P00552,0.824376,NO,59,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-0.952,-3.625,2.673,,0.187,.,L,1.04,0.62,2.648,,50.38,PAH,-1.53,0.520039,0.00280355,0.824376 beta-lactamase_0_D252N,beta-lactamase_0_252,TEM-1,beta-lactamase_0,P62593,0.824419,NO,252,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.0500837,0.00575769,0.824419 kka2_1:4_D118F,kka2_1:4_118,Kka2,kka2_1:4,P00552,0.824454,NO,118,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.07,-4.414,2.344,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.168804,0.0067852,0.824454 kka2_1:8_Q219R,kka2_1:8_219,Kka2,kka2_1:8,P00552,0.82447,NO,219,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-0.93,-2.546,1.616,,0.088,H,A,0.4,-0.85,0.897,,50,HPA,-1.05167,0.100394,0.00237913,0.82447 kka2_1:8_Q219R,kka2_1:8_219,Kka2,kka2_1:8,P00552,0.82447,NO,219,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-0.93,-2.546,1.616,,0.088,H,A,0.4,-0.85,0.897,,50,HPA,-1.05167,0.100394,0.00237913,0.82447 kka2_1:1_A137F,kka2_1:1_137,Kka2,kka2_1:1,P00552,0.824479,NO,137,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.156,-3.905,1.749,,0.029,H,A,0.46,0.34,1.323,,63.26,PHB,-2.559,0.520039,0.00515054,0.824479 kka2_1:1_R122L,kka2_1:1_122,Kka2,kka2_1:1,P00552,0.824496,NO,122,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.175,-3.603,1.428,,0.487,H,A,1.2,0.26,1.356,,71.59,BBH,-1.53833,0.520039,0.00736512,0.824496 beta-lactamase_0_S96D,beta-lactamase_0_96,TEM-1,beta-lactamase_0,P62593,0.824605,NO,96,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.27,-3.641,1.371,,0.368,,b,0.27,0.39,2.516,,73.78,HPP,-2.019,0.0500837,0.00551835,0.824605 kka2_1:8_F263W,kka2_1:8_263,Kka2,kka2_1:8,P00552,0.824694,NO,263,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-0.911,-4.558,3.647,,0.006,G,A,1.62,-0.12,0.928,,45.83,AHH,-0.92,0.100394,0.0172454,0.824694 kka2_1:8_F263W,kka2_1:8_263,Kka2,kka2_1:8,P00552,0.824694,NO,263,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-0.911,-4.558,3.647,,0.006,G,A,1.62,-0.12,0.928,,45.83,AHH,-0.92,0.100394,0.0172454,0.824694 beta-lactamase_0_E56V,beta-lactamase_0_56,TEM-1,beta-lactamase_0,P62593,0.824704,NO,56,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.043,-3.397,1.354,,0.198,E,B,1.04,0.31,1.491,,72.73,HAP,-1.94033,0.0500837,0.00238534,0.824704 beta-lactamase_2500_E272G,beta-lactamase_2500_272,TEM-1,beta-lactamase_2500,P62593,0.824706,NO,272,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.361275,0.00545371,0.824706 beta-lactamase_2500_R176C,beta-lactamase_2500_176,TEM-1,beta-lactamase_2500,P62593,0.824717,NO,176,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-0.863,-5.087,4.224,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.361275,0.00105554,0.824717 kka2_1:2_L152Q,kka2_1:2_152,Kka2,kka2_1:2,P00552,0.824717,NO,152,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.521,-2.735,1.214,,0.547,.,A,0.55,1.36,4.526,,63.64,OHH,-1.162,0.295029,0.00674868,0.824717 kka2_1:4_G201Q,kka2_1:4_201,Kka2,kka2_1:4,P00552,0.824726,NO,201,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.56,-4.001,2.441,,0.149,T,l,0.29,-0.57,0.284,,52.65,POB,-1.92233,0.168804,0.00820117,0.824726 beta-lactamase_0_L150T,beta-lactamase_0_150,TEM-1,beta-lactamase_0,P62593,0.824747,NO,150,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.326,-2.5,1.174,,,H,A,0.55,-0.2,2.128,,62.94,HHB,-1.86167,0.0500837,0.00463171,0.824747 beta-lactamase_0_E119H,beta-lactamase_0_119,TEM-1,beta-lactamase_0,P62593,0.824764,NO,119,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.412,-4.521,3.109,,0.358,H,A,1.04,0.51,3.396,,63.99,BAH,-1.623,0.0500837,0.00386966,0.824764 beta-lactamase_0_G114W,beta-lactamase_0_114,TEM-1,beta-lactamase_0,P62593,0.824773,NO,114,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.094,-5.288,4.194,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.0500837,0.00224919,0.824773 kka2_1:2_Q100A,kka2_1:2_100,Kka2,kka2_1:2,P00552,0.824792,NO,100,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.77,-2.603,-0.167,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.295029,0.0066405,0.824792 kka2_1:1_S11W,kka2_1:1_11,Kka2,kka2_1:1,P00552,0.824804,NO,11,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.322,-5.275,2.953,,0.408,,B,0.77,1.64,2.054,,92.05,OPO,-1.69867,0.520039,0.00381691,0.824804 beta-lactamase_N168V,beta-lactamase_168,TEM-1,beta-lactamase,P62593,0.824841,NO,168,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-1.029,-3.632,2.603,5.42128,0.113,G,A,0.09,-0.4,1.211,,44.41,HPA,-1.13233,0.221079,0.00288667,0.824841 kka2_1:8_T28R,kka2_1:8_28,Kka2,kka2_1:8,P00552,0.824862,NO,28,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.883,-3.259,1.376,,0.353,S,B,0.22,2.02,18.114,18.114,63.64,PPH,-1.74467,0.100394,0.00743084,0.824862 kka2_1:8_T28R,kka2_1:8_28,Kka2,kka2_1:8,P00552,0.824862,NO,28,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.883,-3.259,1.376,,0.353,S,B,0.22,2.02,18.114,18.114,63.64,PPH,-1.74467,0.100394,0.00743084,0.824862 beta-lactamase_0_E210F,beta-lactamase_0_210,TEM-1,beta-lactamase_0,P62593,0.824867,NO,210,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.319,-4.128,1.809,,0.476,H,A,1.04,0.75,3.618,,77.62,HAH,-1.88567,0.0500837,0.00663582,0.824867 beta-lactamase_0_D36Y,beta-lactamase_0_36,TEM-1,beta-lactamase_0,P62593,0.824886,NO,36,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.732,-3.266,0.534,,0.555,H,A,0.75,1.17,13.689,13.689,77.62,AAP,-1.91167,0.0500837,0.00476483,0.824886 beta-lactamase_2500_R92E,beta-lactamase_2500_92,TEM-1,beta-lactamase_2500,P62593,0.824968,NO,92,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.718,-2.624,0.906,,0.479,E,B,1.2,1.36,3.069,,65.38,BBH,-1.50367,0.361275,0.00429626,0.824968 beta-lactamase_0_P143F,beta-lactamase_0_143,TEM-1,beta-lactamase_0,P62593,0.8251,NO,143,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.967,-4.308,3.341,,0.075,H,A,0.52,-0.37,11.868,11.868,66.78,OOB,-1.354,0.0500837,0.00114551,0.8251 Pab1_Y197W,Pab1_197,Pab1,Pab1,P04147,0.825128,NO,197,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-1.345,-4.193,2.848,,,,,,,0.891,,80.42,HHH,-1.41767,0.175299,0.00302474,0.825128 beta-lactamase_M127G,beta-lactamase_127,TEM-1,beta-lactamase,P62593,0.825309,NO,127,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-2.251,-3.785,1.534,5.40552,0.312,S,A,1.07,0.32,1.671,,72.73,PHP,-1.40433,0.221079,0.00437927,0.825309 beta-lactamase_0_R63E,beta-lactamase_0_63,TEM-1,beta-lactamase_0,P62593,0.825327,NO,63,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-0.943,-3.298,2.355,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.0500837,0.00126938,0.825327 kka2_1:1_C31S,kka2_1:1_31,Kka2,kka2_1:1,P00552,0.825348,NO,31,C,S,CS,Special,Polar,5.07,5.68,0.61,112,121,105,-16,108.5,89,-19.5,-2.246,-3.485,1.239,,1.152,S,b,0.46,4.16,8.272,,63.26,OOP,-1.21533,0.520039,0.00681582,0.825348 beta-lactamase_39_L205N,beta-lactamase_39_205,TEM-1,beta-lactamase_39,P62593,0.82549,NO,205,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.922,-4.141,3.219,,,H,A,0.55,-0.46,0.846,,42.31,PHH,-1.57767,0.0495842,0.00255802,0.82549 beta-lactamase_2500_D99L,beta-lactamase_2500_99,TEM-1,beta-lactamase_2500,P62593,0.825533,NO,99,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.191,-3.588,2.397,,0.402,G,A,0.75,0.36,1.318,,64.69,PAH,-1.794,0.361275,0.00305446,0.825533 kka2_1:2_C31N,kka2_1:2_31,Kka2,kka2_1:2,P00552,0.825535,NO,31,C,N,CN,Special,Polar,5.07,5.47157,0.401575,139,121,132,11,108.5,114.1,5.6,-2.246,-3.833,1.587,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.295029,0.00681582,0.825535 kka2_1:1_N58K,kka2_1:1_58,Kka2,kka2_1:1,P00552,0.825551,NO,58,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-2.641,-3.669,1.028,,0.131,S,A,0.61,0.72,30.755,30.755,71.59,HPA,-1.83033,0.520039,0.00793425,0.825551 beta-lactamase_0_F70M,beta-lactamase_0_70,TEM-1,beta-lactamase_0,P62593,0.825561,NO,70,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.169,-3.002,1.833,,,H,A,0.58,-1.34,2.153,,63.99,PHB,-0.980667,0.0500837,0.00193499,0.825561 beta-lactamase_39_W288C,beta-lactamase_39_288,TEM-1,beta-lactamase_39,P62593,0.825574,NO,288,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,,,,,,,,,,,,,BHO,,0.0495842,,0.825574 PSD95pdz3_N363F,PSD95pdz3_363,PSD95pdz3,PSD95pdz3,P31016,0.825582,NO,363,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-1.41,-3.974,2.564,5.23349,,,,,20.7037,,,,HPO,-1.29433,0.0758425,0.000524014,0.825582 kka2_1:2_P167S,kka2_1:2_167,Kka2,kka2_1:2,P00552,0.82559,NO,167,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-2.403,-2.618,0.215,,0.18,H,A,0.52,0.75,3.6,,64.39,HOH,-2.26633,0.295029,0.00543203,0.82559 PSD95pdz3_D348K,PSD95pdz3_348,PSD95pdz3,PSD95pdz3,P31016,0.825632,NO,348,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.264,-3.139,1.875,5.02473,,,,,16.8925,,,,HAH,-1.306,0.0758425,0.000731866,0.825632 beta-lactamase_T69S,beta-lactamase_69,TEM-1,beta-lactamase,P62593,0.825641,NO,69,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-0.973,-2.405,1.432,5.16042,,G,A,0.69,-1.24,0.505,,93.01,PPH,-1.01833,0.221079,0.00127498,0.825641 beta-lactamase_625_L197T,beta-lactamase_625_197,TEM-1,beta-lactamase_625,P62593,0.825646,NO,197,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.853,-3.419,2.566,,0.007,S,B,0.55,0.33,1.756,,60.14,HHP,-1.833,0.213352,0.00144602,0.825646 beta-lactamase_0_G253H,beta-lactamase_0_253,TEM-1,beta-lactamase_0,P62593,0.82567,NO,253,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.0500837,0.00786358,0.82567 kka2_1:1_A14V,kka2_1:1_14,Kka2,kka2_1:1,P00552,0.825684,NO,14,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.837,-2.963,1.126,,0.728,G,A,0.46,0.7,1.17,,71.59,HHH,-1.82567,0.520039,0.00706614,0.825684 kka2_1:8_D62K,kka2_1:8_62,Kka2,kka2_1:8,P00552,0.825729,NO,62,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.591,-3.652,2.061,,0.262,H,A,0.29,0.08,5.58,,64.39,PAA,-1.77833,0.100394,0.00744243,0.825729 kka2_1:8_D62K,kka2_1:8_62,Kka2,kka2_1:8,P00552,0.825729,NO,62,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.591,-3.652,2.061,,0.262,H,A,0.29,0.08,5.58,,64.39,PAA,-1.77833,0.100394,0.00744243,0.825729 beta-lactamase_156_L79Y,beta-lactamase_156_79,TEM-1,beta-lactamase_156,P62593,0.82575,NO,79,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.842,-3.963,3.121,,0.007,H,A,0.55,-0.16,1.831,,50.35,HHP,-1.44333,0.111618,0.000947397,0.82575 kka2_1:1_H139D,kka2_1:1_139,Kka2,kka2_1:1,P00552,0.825893,NO,139,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-2.809,-3.251,0.442,,0.471,H,A,0.17,0.68,1.153,,63.64,BBB,-2.22,0.520039,0.00734779,0.825893 beta-lactamase_0_D212F,beta-lactamase_0_212,TEM-1,beta-lactamase_0,P62593,0.825929,NO,212,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.624,-4.334,2.71,,0.037,,b,0.75,-0.58,3.34,,74.48,HAB,-1.77667,0.0500837,0.00644302,0.825929 beta-lactamase_2500_M270Q,beta-lactamase_2500_270,TEM-1,beta-lactamase_2500,P62593,0.825935,NO,270,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.723,,,,0.422,H,A,1.59,1.15,2.029,,64.34,PHA,-1.70933,0.361275,0.00767762,0.825935 beta-lactamase_156_S104N,beta-lactamase_156_104,TEM-1,beta-lactamase_156,P62593,0.825936,NO,104,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.015,-3.421,2.406,,0.04,,b,0.27,0.57,4.02,,63.29,HPO,-1.05267,0.111618,0.00218083,0.825936 kka2_1:1_E230Q,kka2_1:1_230,Kka2,kka2_1:1,P00552,0.825938,NO,230,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.672,-4.02,1.348,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.520039,0.00920051,0.825938 beta-lactamase_F6P,beta-lactamase_6,TEM-1,beta-lactamase,P62593,0.825955,NO,6,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.847,-4.039,2.192,,,,,,,1.276,,67.83,BHB,-2.076,0.221079,0.00261627,0.825955 kka2_1:4_A9S,kka2_1:4_9,Kka2,kka2_1:4,P00552,0.825961,NO,9,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.079,-2.471,0.392,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.168804,0.00273264,0.825961 kka2_1:1_F264L,kka2_1:1_264,Kka2,kka2_1:1,P00552,0.826025,NO,264,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.02,-2.468,1.448,,0.296,.,?,0.58,0.02,2.303,,71.59,HHNA,-0.9655,0.520039,,0.826025 beta-lactamase_Y103A,beta-lactamase_103,TEM-1,beta-lactamase,P62593,0.826067,NO,103,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-1.33,-3.426,2.096,5.71734,0.613,S,l,2.55,1.21,5.721,,63.29,AHP,-1.48767,0.221079,0.00443048,0.826067 kka2_1:1_A34Q,kka2_1:1_34,Kka2,kka2_1:1,P00552,0.826067,NO,34,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.928,-3.9,2.972,,0.417,.,B,0.46,2.29,0.262,,52.27,AHH,-1.747,0.520039,0.00343484,0.826067 beta-lactamase_A235T,beta-lactamase_235,TEM-1,beta-lactamase,P62593,0.826078,NO,235,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.266,-2.412,1.146,4.83024,0.32,E,B,0.52,-0.86,1.344,,50,OHO,-0.89,0.221079,0.00493474,0.826078 beta-lactamase_M115A,beta-lactamase_115,TEM-1,beta-lactamase,P62593,0.826078,NO,115,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.389,-2.535,1.146,4.89743,0.019,E,B,1.3,0.08,1.236,,69.58,OHP,-1.25433,0.221079,0.0034337,0.826078 WW_domain_G176R,WW_domain_176,Yap65,WW_domain,P46937,0.826094,NO,176,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.235,-2.334,1.099,6.33142,,,,,,2.71,,78.57,HOH,-1.35467,0.153962,0.00288552,0.826094 beta-lactamase_39_S68C,beta-lactamase_39_68,TEM-1,beta-lactamase_39,P62593,0.826098,NO,68,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-0.913,-4.705,3.792,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.0495842,0.000800065,0.826098 beta-lactamase_2500_L47A,beta-lactamase_2500_47,TEM-1,beta-lactamase_2500,P62593,0.826152,NO,47,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.876,-3.301,1.425,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.361275,0.00439844,0.826152 Pab1_A179E,Pab1_179,Pab1,Pab1,P04147,0.826157,NO,179,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.013,-3.257,2.244,,0.078,H,A,0.61,0.5,,,,HHB,-1.51233,0.175299,0.000291703,0.826157 beta-lactamase_G76C,beta-lactamase_76,TEM-1,beta-lactamase,P62593,0.82616,NO,76,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.189,-4.823,3.634,4.73862,,H,A,2.05,-0.67,3.059,,67.83,OOH,-1.22267,0.221079,0.00476637,0.82616 kka2_1:8_L60R,kka2_1:8_60,Kka2,kka2_1:8,P00552,0.826232,NO,60,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.997,-4.088,3.091,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.100394,0.00262176,0.826232 kka2_1:8_L60R,kka2_1:8_60,Kka2,kka2_1:8,P00552,0.826232,NO,60,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.997,-4.088,3.091,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.100394,0.00262176,0.826232 beta-lactamase_0_A185N,beta-lactamase_0_185,TEM-1,beta-lactamase_0,P62593,0.826245,NO,185,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.406,-4.005,2.599,,,H,A,0.46,-1.02,1.203,,65.03,HHP,-1.84033,0.0500837,0.00467449,0.826245 kka2_1:8_F37Q,kka2_1:8_37,Kka2,kka2_1:8,P00552,0.826316,NO,37,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.427,-4.273,2.846,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.100394,0.00586193,0.826316 kka2_1:8_F37Q,kka2_1:8_37,Kka2,kka2_1:8,P00552,0.826316,NO,37,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.427,-4.273,2.846,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.100394,0.00586193,0.826316 beta-lactamase_G141E,beta-lactamase_141,TEM-1,beta-lactamase,P62593,0.826456,NO,141,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.828,-2.606,1.778,5.03155,0.575,T,l,0.76,-0.28,0.198,,64.69,HOO,-1.08933,0.221079,0.0012419,0.826456 beta-lactamase_M268E,beta-lactamase_268,TEM-1,beta-lactamase,P62593,0.826456,NO,268,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-2.023,-3.822,1.799,5.4797,0.471,H,A,0.09,0.3,1.071,,65.73,PHA,-2.16233,0.221079,0.0102525,0.826456 kka2_1:8_L259V,kka2_1:8_259,Kka2,kka2_1:8,P00552,0.826594,NO,259,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.088,-2.47,1.382,,0.036,H,A,1.59,-0.15,1.83,,48.48,BHH,-1.15167,0.100394,0.0206964,0.826594 kka2_1:8_L259V,kka2_1:8_259,Kka2,kka2_1:8,P00552,0.826594,NO,259,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.088,-2.47,1.382,,0.036,H,A,1.59,-0.15,1.83,,48.48,BHH,-1.15167,0.100394,0.0206964,0.826594 kka2_1:8_V198L,kka2_1:8_198,Kka2,kka2_1:8,P00552,0.826594,NO,198,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.719,-3.148,1.429,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.100394,0.00835002,0.826594 kka2_1:8_V198L,kka2_1:8_198,Kka2,kka2_1:8,P00552,0.826594,NO,198,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.719,-3.148,1.429,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.100394,0.00835002,0.826594 beta-lactamase_A185V,beta-lactamase_185,TEM-1,beta-lactamase,P62593,0.826598,NO,185,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.406,-2.093,0.687,4.89877,,H,A,2.34,-1.02,2.999,,65.03,HHP,-1.84033,0.221079,0.00467449,0.826598 beta-lactamase_0_E175T,beta-lactamase_0_175,TEM-1,beta-lactamase_0,P62593,0.826619,NO,175,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.336,-3.551,1.215,,0.551,,A,1.04,1.05,2.334,,77.62,AAB,-1.31233,0.0500837,0.00482205,0.826619 beta-lactamase_0_K144S,beta-lactamase_0_144,TEM-1,beta-lactamase_0,P62593,0.826663,NO,144,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-2.388,-2.51,0.122,,0.863,H,A,2.34,1.27,5.696,,77.62,OBA,-1.904,0.0500837,0.00481141,0.826663 kka2_1:2_P179Q,kka2_1:2_179,Kka2,kka2_1:2,P00552,0.826716,NO,179,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.974,-4.023,3.049,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.295029,0.00298346,0.826716 beta-lactamase_G43S,beta-lactamase_43,TEM-1,beta-lactamase,P62593,0.826722,NO,43,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.62,-3.161,2.541,5.28886,,E,B,0.77,-0.78,,,,HOH,-1.577,0.221079,0.00120151,0.826722 beta-lactamase_0_G265E,beta-lactamase_0_265,TEM-1,beta-lactamase_0,P62593,0.826747,NO,265,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.0500837,0.00811926,0.826747 beta-lactamase_0_N134M,beta-lactamase_0_134,TEM-1,beta-lactamase_0,P62593,0.826747,NO,134,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-0.879,-4.702,3.823,,0.138,H,A,0.61,-0.6,3.776,,53.15,HPH,-1.02233,0.0500837,0.000644786,0.826747 beta-lactamase_C75M,beta-lactamase_75,TEM-1,beta-lactamase,P62593,0.82677,NO,75,C,M,CM,Special,Hydrophobic,5.07,5.74,0.67,196,121,149,28,108.5,162.9,54.4,-1.245,-4.597,3.352,4.88171,,H,A,0.25,-0.87,0.876,,50,HOO,-1.24333,0.221079,0.0034616,0.82677 kka2_1:4_L241V,kka2_1:4_241,Kka2,kka2_1:4,P00552,0.82677,NO,241,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.158,-3.12,1.962,,0.08,H,A,0.55,-0.82,1.598,,63.26,HHH,-1.58533,0.168804,0.0117299,0.82677 WW_domain_T196A,WW_domain_196,Yap65,WW_domain,P46937,0.826926,NO,196,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.782,-2.965,1.183,5.5744,,,,,,5.836,,70.04,PPP,-1.732,0.153962,0.00421377,0.826926 beta-lactamase_0_T179C,beta-lactamase_0_179,TEM-1,beta-lactamase_0,P62593,0.826928,NO,179,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.085,-4.712,3.627,,,E,B,0.22,-1.38,0.367,,73.08,PPH,-1.557,0.0500837,0.00226045,0.826928 kka2_1:4_I228V,kka2_1:4_228,Kka2,kka2_1:4,P00552,0.826981,NO,228,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.142,-1.946,0.804,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.168804,0.00458834,0.826981 beta-lactamase_0_L111G,beta-lactamase_0_111,TEM-1,beta-lactamase_0,P62593,0.827042,NO,111,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.76,-3.666,1.906,,0.328,T,A,0.55,0.93,1.966,,64.34,BHP,-1.884,0.0500837,0.00480671,0.827042 kka2_1:1_I196R,kka2_1:1_196,Kka2,kka2_1:1,P00552,0.827063,NO,196,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-2.115,-4.247,2.132,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.520039,0.0107273,0.827063 Pab1_A158D,Pab1_158,Pab1,Pab1,P04147,0.827078,NO,158,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.154,-3.614,2.46,,,,,,,1.197,,56.33,HHP,-1.40733,0.175299,0.000649733,0.827078 kka2_1:1_L243Q,kka2_1:1_243,Kka2,kka2_1:1,P00552,0.827131,NO,243,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-2.651,-2.876,0.225,,0.277,H,A,0.55,-0.67,4.334,,92.05,HHH,-2.03767,0.520039,0.00884927,0.827131 beta-lactamase_156_R242E,beta-lactamase_156_242,TEM-1,beta-lactamase_156,P62593,0.827194,NO,242,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.111618,0.00452879,0.827194 beta-lactamase_0_E195N,beta-lactamase_0_195,TEM-1,beta-lactamase_0,P62593,0.827234,NO,195,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.186,-2.977,0.791,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.0500837,0.00496565,0.827234 beta-lactamase_0_G85E,beta-lactamase_0_85,TEM-1,beta-lactamase_0,P62593,0.827258,NO,85,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.011,-3.408,2.397,,0.805,T,l,0.29,1.7,2.25,,63.64,HOP,-1.68733,0.0500837,0.00252173,0.827258 beta-lactamase_L192A,beta-lactamase_192,TEM-1,beta-lactamase,P62593,0.827426,NO,192,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.254,-2.317,1.063,5.68899,0.095,H,A,1.3,0.35,1.756,,60.14,HHP,-1.41833,0.221079,0.00558728,0.827426 beta-lactamase_2500_V78M,beta-lactamase_2500_78,TEM-1,beta-lactamase_2500,P62593,0.827502,NO,78,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.459,-2.823,1.364,,,H,A,0.44,-0.47,31.376,31.376,63.64,HHH,-1.17833,0.361275,0.00492501,0.827502 beta-lactamase_0_W208N,beta-lactamase_0_208,TEM-1,beta-lactamase_0,P62593,0.827504,NO,208,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-0.818,-4.348,3.53,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.0500837,0.00126609,0.827504 kka2_1:8_P132T,kka2_1:8_132,Kka2,kka2_1:8,P00552,0.82754,NO,132,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.775,-3.417,2.642,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.100394,0.0018489,0.82754 kka2_1:8_P132T,kka2_1:8_132,Kka2,kka2_1:8,P00552,0.82754,NO,132,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.775,-3.417,2.642,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.100394,0.0018489,0.82754 beta-lactamase_625_R257H,beta-lactamase_625_257,TEM-1,beta-lactamase_625,P62593,0.82758,NO,257,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.213352,0.00756629,0.82758 beta-lactamase_G142N,beta-lactamase_142,TEM-1,beta-lactamase,P62593,0.827584,NO,142,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.707,-3.445,2.738,4.55474,0.034,,p,0.77,-0.64,1.947,,64.69,OOO,-0.834,0.221079,0.00060149,0.827584 beta-lactamase_0_P165Q,beta-lactamase_0_165,TEM-1,beta-lactamase_0,P62593,0.827597,NO,165,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.373,-3.97,2.597,,0.203,T,A,0.52,-0.31,3.242,,73.78,AOA,-1.359,0.0500837,0.00549538,0.827597 beta-lactamase_2500_F149A,beta-lactamase_2500_149,TEM-1,beta-lactamase_2500,P62593,0.827635,NO,149,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.299,-3.341,2.042,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.361275,0.00418462,0.827635 beta-lactamase_E166P,beta-lactamase_166,TEM-1,beta-lactamase,P62593,0.82765,NO,166,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.756,-3.897,2.141,5.60527,0.508,G,A,0.52,1.05,2.124,,73.08,OAH,-1.42233,0.221079,0.00512989,0.82765 beta-lactamase_0_G226K,beta-lactamase_0_226,TEM-1,beta-lactamase_0,P62593,0.827682,NO,226,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.461,-2.859,1.398,,0.701,T,l,0.29,-0.25,23.034,23.034,74.48,HOH,-1.42933,0.0500837,0.00665294,0.827682 beta-lactamase_0_L55M,beta-lactamase_0_55,TEM-1,beta-lactamase_0,P62593,0.827687,NO,55,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.86,-4.329,2.469,,0.372,E,A,0.55,-0.36,1.967,,63.99,HHA,-2.247,0.0500837,0.00403741,0.827687 beta-lactamase_V82Q,beta-lactamase_82,TEM-1,beta-lactamase,P62593,0.827709,NO,82,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.325,-4.196,2.871,5.27777,0.267,H,A,0.96,0.08,1.379,,93.01,BHA,-1.28567,0.221079,0.00397046,0.827709 beta-lactamase_0_L137C,beta-lactamase_0_137,TEM-1,beta-lactamase_0,P62593,0.827797,NO,137,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.03,-4.702,3.672,,,H,A,0.55,-0.38,0.328,,42.31,HHP,-1.58933,0.0500837,0.00278599,0.827797 kka2_1:1_D90H,kka2_1:1_90,Kka2,kka2_1:1,P00552,0.827841,NO,90,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.459,-2.113,-0.346,,0.104,E,B,0.75,0.73,6.085,,64.39,BAH,-1.72833,0.520039,0.00583842,0.827841 beta-lactamase_F22V,beta-lactamase_22,TEM-1,beta-lactamase,P62593,0.827896,NO,22,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-2.676,-2.716,0.04,,,,,,,1.616,,73.08,HHH,-2.03233,0.221079,0.00262842,0.827896 beta-lactamase_625_R118P,beta-lactamase_625_118,TEM-1,beta-lactamase_625,P62593,0.8279,NO,118,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.413,-3.946,1.533,,0.457,H,A,1.2,1.39,2.144,,77.62,HBA,-1.785,0.213352,0.00538794,0.8279 kka2_1:1_V83L,kka2_1:1_83,Kka2,kka2_1:1,P00552,0.82792,NO,83,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-2.567,-2.63,0.063,,0.358,E,B,0.44,0.53,5.931,,71.59,AHH,-2.264,0.520039,0.00650486,0.82792 beta-lactamase_0_N134R,beta-lactamase_0_134,TEM-1,beta-lactamase_0,P62593,0.827957,NO,134,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-0.879,-3.446,2.567,,0.138,H,A,0.61,-0.6,3.776,,53.15,HPH,-1.02233,0.0500837,0.000644786,0.827957 beta-lactamase_T116V,beta-lactamase_116,TEM-1,beta-lactamase,P62593,0.82796,NO,116,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.28,-3.415,2.135,4.78335,0.115,E,B,0.69,-0.12,0.343,,67.48,HPH,-1.39967,0.221079,0.00336175,0.82796 kka2_1:4_L19R,kka2_1:4_19,Kka2,kka2_1:4,P00552,0.828029,NO,19,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.254,-4.143,2.889,,0.08,T,A,1.59,-0.26,2.645,,65.53,BHH,-2.221,0.168804,0.00620703,0.828029 beta-lactamase_I54N,beta-lactamase_54,TEM-1,beta-lactamase,P62593,0.828127,NO,54,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-2.838,-2.849,0.011,5.40541,0.669,E,B,0.77,-0.14,3.946,,73.78,BHH,-2.337,0.221079,0.00403589,0.828127 beta-lactamase_L28E,beta-lactamase_28,TEM-1,beta-lactamase,P62593,0.828127,NO,28,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.579,-3.677,2.098,5.42969,0.277,H,A,0.07,-0.16,19.748,19.748,93.01,PHH,-2.11333,0.221079,0.00359321,0.828127 beta-lactamase_0_V42A,beta-lactamase_0_42,TEM-1,beta-lactamase_0,P62593,0.828264,NO,42,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.564,-2.554,0.99,,0.017,E,B,0.44,-0.51,1.659,,63.99,BHO,-1.042,0.0500837,0.00404515,0.828264 beta-lactamase_0_V31E,beta-lactamase_0_31,TEM-1,beta-lactamase_0,P62593,0.828278,NO,31,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.822,-3.908,2.086,,,H,A,0.44,-0.46,4.126,,73.78,BHB,-2.03767,0.0500837,0.00478065,0.828278 beta-lactamase_G242C,beta-lactamase_242,TEM-1,beta-lactamase,P62593,0.82828,NO,242,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.319,-5.013,3.694,4.68003,,E,B,0.87,-1.05,1.079,,50,BOH,-1.428,0.221079,0.00452879,0.82828 gb1_A249T,gb1_249,gb1,gb1,P06654,0.828289,NO,249,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.739,-2.12,0.381,,,,,,,0.252,,44.87,AHH,-1.67367,0.177985,0.00333585,0.828289 beta-lactamase_0_G154Q,beta-lactamase_0_154,TEM-1,beta-lactamase_0,P62593,0.828369,NO,154,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.823,-4.083,3.26,,0.54,T,l,0.29,-0.56,3.629,,64.69,HOA,-1.635,0.0500837,0.00180205,0.828369 beta-lactamase_0_K144Y,beta-lactamase_0_144,TEM-1,beta-lactamase_0,P62593,0.828379,NO,144,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-2.388,-4.321,1.933,,0.863,H,A,2.34,1.27,5.696,,77.62,OBA,-1.904,0.0500837,0.00481141,0.828379 beta-lactamase_0_F70V,beta-lactamase_0_70,TEM-1,beta-lactamase_0,P62593,0.828407,NO,70,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.169,-2.579,1.41,,,H,A,0.58,-1.34,2.153,,63.99,PHB,-0.980667,0.0500837,0.00193499,0.828407 PSD95pdz3_R318N,PSD95pdz3_318,PSD95pdz3,PSD95pdz3,P31016,0.828411,NO,318,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.582,-3.13,1.548,4.94876,,,,,17.5609,,,,BBO,-1.40567,0.0758425,0.00110471,0.828411 beta-lactamase_2500_T107V,beta-lactamase_2500_107,TEM-1,beta-lactamase_2500,P62593,0.828415,NO,107,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.117,-3.226,2.109,,,G,A,0.22,-0.06,2.686,,67.83,HPA,-1.265,0.361275,0.00239347,0.828415 beta-lactamase_P224D,beta-lactamase_224,TEM-1,beta-lactamase,P62593,0.828437,NO,224,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.893,-3.513,2.62,5.179,0.383,,B,0.99,-0.3,0.383,,74.48,HOH,-1.26433,0.221079,0.00189564,0.828437 beta-lactamase_0_L74H,beta-lactamase_0_74,TEM-1,beta-lactamase_0,P62593,0.828444,NO,74,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.296,-4.896,3.6,,,H,A,0.55,-0.91,1.46,,50,HHO,-1.34933,0.0500837,0.00493255,0.828444 beta-lactamase_0_G281M,beta-lactamase_0_281,TEM-1,beta-lactamase_0,P62593,0.828458,NO,281,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.0500837,0.0406482,0.828458 kka2_1:1_H8Q,kka2_1:1_8,Kka2,kka2_1:1,P00552,0.828569,NO,8,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-2.759,-2.66,-0.099,,,,,,,16.971,16.971,71.59,HBH,-2.25467,0.520039,0.00256422,0.828569 beta-lactamase_T198I,beta-lactamase_198,TEM-1,beta-lactamase,P62593,0.828621,NO,198,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.168,-3.831,1.663,4.9209,0.489,,B,0.69,-0.13,0.37,,73.78,HPH,-1.98767,0.221079,0.004311,0.828621 beta-lactamase_2500_M127K,beta-lactamase_2500_127,TEM-1,beta-lactamase_2500,P62593,0.828715,NO,127,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-2.251,-3,0.749,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.361275,0.00437927,0.828715 beta-lactamase_2500_T187I,beta-lactamase_2500_187,TEM-1,beta-lactamase_2500,P62593,0.828748,NO,187,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.401,-2.871,1.47,,0.007,H,A,0.22,-1.19,3.91,,67.48,PPH,-1.69633,0.361275,0.00491782,0.828748 gb1_A249C,gb1_249,gb1,gb1,P06654,0.828757,NO,249,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.739,-4.522,2.783,,,,,,,0.252,,44.87,AHH,-1.67367,0.177985,0.00333585,0.828757 gb1_N263H,gb1_263,gb1,gb1,P06654,0.828757,NO,263,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-1.162,-3.782,2.62,,,,,,,,,,APO,-2.04233,0.177985,0.0035297,0.828757 beta-lactamase_39_A246Y,beta-lactamase_39_246,TEM-1,beta-lactamase_39,P62593,0.82877,NO,246,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.121,-4.018,1.897,,0.01,E,B,0.46,-1.01,1.331,,73.78,HHH,-1.55633,0.0495842,0.00569458,0.82877 beta-lactamase_L247T,beta-lactamase_247,TEM-1,beta-lactamase,P62593,0.828806,NO,247,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.48,-2.736,1.256,5.28771,0.007,E,B,2.89,-0.72,2.951,,63.99,HHO,-1.79833,0.221079,0.00611275,0.828806 beta-lactamase_2500_P250A,beta-lactamase_2500_250,TEM-1,beta-lactamase_2500,P62593,0.828842,NO,250,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.361275,0.00550899,0.828842 beta-lactamase_0_A282T,beta-lactamase_0_282,TEM-1,beta-lactamase_0,P62593,0.82886,NO,282,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.0500837,0.0449821,0.82886 kka2_1:2_S40G,kka2_1:2_40,Kka2,kka2_1:2,P00552,0.828899,NO,40,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.645,-3.566,0.921,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.295029,0.00693477,0.828899 kka2_1:4_I228Q,kka2_1:4_228,Kka2,kka2_1:4,P00552,0.828982,NO,228,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.142,-4.362,3.22,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.168804,0.00458834,0.828982 beta-lactamase_0_L146N,beta-lactamase_0_146,TEM-1,beta-lactamase_0,P62593,0.828995,NO,146,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.462,-4.208,2.746,,0.007,H,A,0.55,-0.56,2.051,,64.69,AHP,-1.656,0.0500837,0.00474542,0.828995 beta-lactamase_0_S233R,beta-lactamase_0_233,TEM-1,beta-lactamase_0,P62593,0.829009,NO,233,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.886,-3.819,1.933,,0.016,E,B,0.27,-1.01,3.579,,77.62,BPO,-1.17267,0.0500837,0.00311415,0.829009 beta-lactamase_A222W,beta-lactamase_222,TEM-1,beta-lactamase,P62593,0.829071,NO,222,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.103,-5.409,3.306,5.2262,0.233,H,A,0.47,-0.25,0.379,,77.62,PHH,-1.63733,0.221079,0.00466094,0.829071 beta-lactamase_G85F,beta-lactamase_85,TEM-1,beta-lactamase,P62593,0.829071,NO,85,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.011,-4.377,3.366,5.58951,0.805,T,l,0.23,1.7,1.468,,63.64,HOP,-1.68733,0.221079,0.00252173,0.829071 kka2_1:4_L67V,kka2_1:4_67,Kka2,kka2_1:4,P00552,0.829097,NO,67,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.741,-2.882,2.141,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.168804,0.00102787,0.829097 beta-lactamase_0_T187Y,beta-lactamase_0_187,TEM-1,beta-lactamase_0,P62593,0.82911,NO,187,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.401,-4.271,2.87,,0.007,H,A,0.22,-1.19,3.259,,67.48,PPH,-1.69633,0.0500837,0.00491782,0.82911 kka2_1:2_W24C,kka2_1:2_24,Kka2,kka2_1:2,P00552,0.829142,NO,24,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-1.779,-3.129,1.35,,0.477,E,B,1.51,-0.21,2.666,,56.06,AHH,-2.24467,0.295029,0.00631564,0.829142 beta-lactamase_L10H,beta-lactamase_10,TEM-1,beta-lactamase,P62593,0.829151,NO,10,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.623,-4.815,3.192,,,,,,,2.467,,65.38,HHH,-1.83833,0.221079,0.00296968,0.829151 kka2_1:8_P76F,kka2_1:8_76,Kka2,kka2_1:8,P00552,0.829175,NO,76,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.449,-4.424,2.975,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.100394,0.00625685,0.829175 kka2_1:8_P76F,kka2_1:8_76,Kka2,kka2_1:8,P00552,0.829175,NO,76,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.449,-4.424,2.975,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.100394,0.00625685,0.829175 beta-lactamase_0_Y103D,beta-lactamase_0_103,TEM-1,beta-lactamase_0,P62593,0.829188,NO,103,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-1.33,-3.794,2.464,,0.613,S,l,0.21,1.21,1.646,,63.29,AHP,-1.48767,0.0500837,0.00443048,0.829188 beta-lactamase_0_T69C,beta-lactamase_0_69,TEM-1,beta-lactamase_0,P62593,0.829229,NO,69,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-0.973,-4.661,3.688,,,G,A,0.22,-1.24,0.505,,93.01,PPH,-1.01833,0.0500837,0.00127498,0.829229 kka2_1:2_G164L,kka2_1:2_164,Kka2,kka2_1:2,P00552,0.829236,NO,164,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.869,-3.829,2.96,,0.862,T,l,0.75,1.45,1.539,,64.39,POH,-1.828,0.295029,0.00442091,0.829236 beta-lactamase_0_P181H,beta-lactamase_0_181,TEM-1,beta-lactamase_0,P62593,0.829295,NO,181,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.813,-4.706,3.893,,,H,A,0.52,-1.14,1.357,,61.54,HOH,-1.795,0.0500837,0.000703122,0.829295 beta-lactamase_39_T69Q,beta-lactamase_39_69,TEM-1,beta-lactamase_39,P62593,0.829321,NO,69,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-0.973,-3.935,2.962,,,G,A,0.22,-1.24,4.194,,93.01,PPH,-1.01833,0.0495842,0.00127498,0.829321 beta-lactamase_0_L248D,beta-lactamase_0_248,TEM-1,beta-lactamase_0,P62593,0.829334,NO,248,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.0500837,0.00428493,0.829334 beta-lactamase_R255V,beta-lactamase_255,TEM-1,beta-lactamase,P62593,0.829348,NO,255,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.266,-2.088,-0.178,5.55882,0.141,E,B,0.68,0.38,1.199,,63.99,PBH,-2.00433,0.221079,0.00499612,0.829348 kka2_1:4_A229F,kka2_1:4_229,Kka2,kka2_1:4,P00552,0.829426,NO,229,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.739,-4.384,2.645,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.168804,0.00942138,0.829426 beta-lactamase_P143Q,beta-lactamase_143,TEM-1,beta-lactamase,P62593,0.829443,NO,143,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.967,-4.024,3.057,5.16366,0.075,H,A,0.99,-0.37,0.479,,66.78,OOB,-1.354,0.221079,0.00114551,0.829443 beta-lactamase_0_H287R,beta-lactamase_0_287,TEM-1,beta-lactamase_0,P62593,0.829462,NO,287,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,,,,,,,,,,,,,BBH,-1.111,0.0500837,,0.829462 PSD95pdz3_V328F,PSD95pdz3_328,PSD95pdz3,PSD95pdz3,P31016,0.829471,NO,328,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.465,-3.524,2.059,5.28275,,,,,16.8775,,,,HHO,-1.36767,0.0758425,0.000986706,0.829471 beta-lactamase_0_D83W,beta-lactamase_0_83,TEM-1,beta-lactamase_0,P62593,0.829494,NO,83,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.066,-5.509,4.443,,0.354,H,A,0.75,0.22,0.617,,48.95,HAH,-1.34733,0.0500837,0.00205968,0.829494 PSD95pdz3_I388Q,PSD95pdz3_388,PSD95pdz3,PSD95pdz3,P31016,0.829521,NO,388,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.63,-4.031,2.401,5.17282,,,,,16.0025,,,,PHH,-1.54967,0.0758425,0.000151216,0.829521 kka2_1:1_D5S,kka2_1:1_5,Kka2,kka2_1:1,P00552,0.829559,NO,5,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.306,-2.972,1.666,,,,,,,0.895,,71.59,PAO,-1.784,0.520039,0.00222864,0.829559 PSD95pdz3_G344V,PSD95pdz3_344,PSD95pdz3,PSD95pdz3,P31016,0.82957,NO,344,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.008,-3.435,2.427,4.83855,,,,,14.06,,,,HOO,-1.10767,0.0758425,0.00078498,0.82957 Pab1_I157H,Pab1_157,Pab1,Pab1,P04147,0.829573,NO,157,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.623,-4.793,3.17,,,,,,,1.439,,79.72,BHH,-1.28667,0.175299,0.0018103,0.829573 kka2_1:1_L81R,kka2_1:1_81,Kka2,kka2_1:1,P00552,0.829646,NO,81,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.427,-4.145,2.718,,0.46,E,A,0.55,-0.14,0.374,,63.64,HHA,-1.50567,0.520039,0.00805839,0.829646 beta-lactamase_L38E,beta-lactamase_38,TEM-1,beta-lactamase,P62593,0.829678,NO,38,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.343,-3.797,2.454,5.23728,0.088,H,A,1.75,0.2,1.986,,64.34,PHO,-1.78033,0.221079,0.00373244,0.829678 gb1_D266P,gb1_266,gb1,gb1,P06654,0.829687,NO,266,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.261,-3.604,2.343,,,,,,,0.638,,45.54,HAO,-1.59333,0.177985,0.00394694,0.829687 kka2_1:8_A137G,kka2_1:8_137,Kka2,kka2_1:8,P00552,0.8297,NO,137,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.156,-3.64,1.484,,0.029,H,A,1.04,0.34,2.886,,63.26,PHB,-2.559,0.100394,0.00515054,0.8297 kka2_1:8_A137G,kka2_1:8_137,Kka2,kka2_1:8,P00552,0.8297,NO,137,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.156,-3.64,1.484,,0.029,H,A,1.04,0.34,2.886,,63.26,PHB,-2.559,0.100394,0.00515054,0.8297 kka2_1:4_A71Y,kka2_1:4_71,Kka2,kka2_1:4,P00552,0.829707,NO,71,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.824,-4.36,2.536,,0.553,H,A,0.46,0.08,5.76,,64.39,HHP,-1.74033,0.168804,0.00727707,0.829707 beta-lactamase_0_D161I,beta-lactamase_0_161,TEM-1,beta-lactamase_0,P62593,0.829719,NO,161,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.891,-4.034,3.143,,0.341,,A,0.75,-0.52,0.795,,61.19,HAB,-0.961333,0.0500837,0.000897697,0.829719 beta-lactamase_0_A268E,beta-lactamase_0_268,TEM-1,beta-lactamase_0,P62593,0.829744,NO,268,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.0500837,0.0102525,0.829744 kka2_1:8_A119W,kka2_1:8_119,Kka2,kka2_1:8,P00552,0.829783,NO,119,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.073,-5.403,4.33,,0.019,H,A,0.46,-0.57,1.511,,71.59,AHH,-2.34,0.100394,0.00441074,0.829783 kka2_1:8_A119W,kka2_1:8_119,Kka2,kka2_1:8,P00552,0.829783,NO,119,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.073,-5.403,4.33,,0.019,H,A,0.46,-0.57,1.511,,71.59,AHH,-2.34,0.100394,0.00441074,0.829783 beta-lactamase_L146A,beta-lactamase_146,TEM-1,beta-lactamase,P62593,0.829867,NO,146,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.462,-3.204,1.742,5.62483,0.007,H,A,1.3,-0.56,1.953,,64.69,AHP,-1.656,0.221079,0.00474542,0.829867 beta-lactamase_0_P60A,beta-lactamase_0_60,TEM-1,beta-lactamase_0,P62593,0.829914,NO,60,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-2.469,-1.436,-1.033,,0.256,T,A,0.52,-0.56,3.653,,77.62,BOA,-1.97633,0.0500837,0.00521318,0.829914 beta-lactamase_0_K32L,beta-lactamase_0_32,TEM-1,beta-lactamase_0,P62593,0.829948,NO,32,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.984,-2.812,0.828,,0.563,H,A,2.34,0.34,0.418,,73.08,HBA,-2.04233,0.0500837,0.00401283,0.829948 kka2_1:8_S104E,kka2_1:8_104,Kka2,kka2_1:8,P00552,0.829976,NO,104,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.436,-2.627,1.191,,0.536,T,A,0.27,-1.11,1.689,,63.64,HPP,-1.91433,0.100394,0.00555207,0.829976 kka2_1:8_S104E,kka2_1:8_104,Kka2,kka2_1:8,P00552,0.829976,NO,104,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.436,-2.627,1.191,,0.536,T,A,0.27,-1.11,1.689,,63.64,HPP,-1.91433,0.100394,0.00555207,0.829976 beta-lactamase_0_L199R,beta-lactamase_0_199,TEM-1,beta-lactamase_0,P62593,0.829991,NO,199,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-2.942,-3.181,0.239,,0.832,H,A,0.55,0.42,10.85,10.85,77.62,PHH,-2.32933,0.0500837,0.0048649,0.829991 WW_domain_Q200K,WW_domain_200,Yap65,WW_domain,P46937,0.830032,NO,200,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-1.599,-2.029,0.43,5.37476,,,,,,1.9,,70.04,HPA,-1.484,0.153962,0.00300397,0.830032 beta-lactamase_625_H110D,beta-lactamase_625_110,TEM-1,beta-lactamase_625,P62593,0.830038,NO,110,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-1.706,-3.678,1.972,,0.341,G,a,0.17,1.08,31.31,31.31,64.69,BBH,-1.73333,0.213352,0.00441499,0.830038 beta-lactamase_2500_V106C,beta-lactamase_2500_106,TEM-1,beta-lactamase_2500,P62593,0.830055,NO,106,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.218,-4.774,3.556,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.361275,0.00304168,0.830055 beta-lactamase_0_V101M,beta-lactamase_0_101,TEM-1,beta-lactamase_0,P62593,0.830108,NO,101,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.295,-2.812,1.517,,0.342,,B,0.44,0,1.61,,73.08,HHA,-1.54367,0.0500837,0.00374492,0.830108 beta-lactamase_0_Y262G,beta-lactamase_0_262,TEM-1,beta-lactamase_0,P62593,0.830154,NO,262,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.0500837,0.00853516,0.830154 kka2_1:2_D154A,kka2_1:2_154,Kka2,kka2_1:2,P00552,0.830178,NO,154,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.876,-3.364,2.488,,0.457,,b,0.29,1.48,3.631,,52.65,HAP,-1.52467,0.295029,0.00292633,0.830178 beta-lactamase_0_G226I,beta-lactamase_0_226,TEM-1,beta-lactamase_0,P62593,0.830187,NO,226,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.461,-4.177,2.716,,0.701,T,l,0.29,-0.25,23.034,23.034,74.48,HOH,-1.42933,0.0500837,0.00665294,0.830187 kka2_1:4_L103G,kka2_1:4_103,Kka2,kka2_1:4,P00552,0.830204,NO,103,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-2.362,-2.706,0.344,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.168804,0.00574792,0.830204 kka2_1:1_L102R,kka2_1:1_102,Kka2,kka2_1:1,P00552,0.830238,NO,102,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.804,-3.959,3.155,,,T,A,0.55,-1.17,4.258,,42.42,AHH,-1.398,0.520039,0.00201332,0.830238 kka2_1:1_E161Q,kka2_1:1_161,Kka2,kka2_1:1,P00552,0.830266,NO,161,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.581,-3.792,2.211,,0.829,G,A,1.04,2.24,1.612,,92.05,AAB,-1.861,0.520039,0.00760103,0.830266 kka2_1:1_G234Y,kka2_1:1_234,Kka2,kka2_1:1,P00552,0.830268,NO,234,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-2.9,-4.454,1.554,,0.494,H,A,0.29,-0.29,1.753,,71.59,OOA,-1.86767,0.520039,0.00984449,0.830268 kka2_1:2_A79V,kka2_1:2_79,Kka2,kka2_1:2,P00552,0.830272,NO,79,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.368,-2.938,0.57,,0.563,.,B,0.46,-0.43,0.475,,71.59,HHH,-1.752,0.295029,0.00664821,0.830272 beta-lactamase_P165Q,beta-lactamase_165,TEM-1,beta-lactamase,P62593,0.830288,NO,165,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.373,-3.97,2.597,5.33889,0.203,T,A,0.99,-0.31,0.414,,73.78,AOA,-1.359,0.221079,0.00549538,0.830288 beta-lactamase_2500_A185S,beta-lactamase_2500_185,TEM-1,beta-lactamase_2500,P62593,0.830292,NO,185,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.406,-3.291,1.885,,,H,A,0.46,-1.02,2.999,,65.03,HHP,-1.84033,0.361275,0.00467449,0.830292 PSD95pdz3_L342E,PSD95pdz3_342,PSD95pdz3,PSD95pdz3,P31016,0.830331,NO,342,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.347,-3.572,2.225,5.03015,,,,,12.0762,,,,HHH,-1.428,0.0758425,0.00081112,0.830331 beta-lactamase_L73Y,beta-lactamase_73,TEM-1,beta-lactamase,P62593,0.830351,NO,73,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.507,-3.917,2.41,5.84139,,H,A,1.75,-0.64,2.09,,67.83,HHH,-1.487,0.221079,0.00488983,0.830351 Pab1_G167W,Pab1_167,Pab1,Pab1,P04147,0.830381,NO,167,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.223,-5.066,3.843,,0.195,S,g,,0.03,,,,BOH,-1.25133,0.175299,0.00146449,0.830381 kka2_1:8_D157R,kka2_1:8_157,Kka2,kka2_1:8,P00552,0.830389,NO,157,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.993,-3.936,2.943,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.100394,0.0042313,0.830389 kka2_1:8_D157R,kka2_1:8_157,Kka2,kka2_1:8,P00552,0.830389,NO,157,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.993,-3.936,2.943,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.100394,0.0042313,0.830389 beta-lactamase_2500_T116N,beta-lactamase_2500_116,TEM-1,beta-lactamase_2500,P62593,0.830404,NO,116,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.28,-2.515,1.235,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.361275,0.00336175,0.830404 beta-lactamase_0_P105D,beta-lactamase_0_105,TEM-1,beta-lactamase_0,P62593,0.830441,NO,105,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.813,-3.466,2.653,,0.226,T,A,0.52,0.8,3.48,,63.29,POH,-1.01533,0.0500837,0.0011981,0.830441 beta-lactamase_A182P,beta-lactamase_182,TEM-1,beta-lactamase,P62593,0.830504,NO,182,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.777,-3.952,2.175,4.98609,0.136,H,A,0.52,-0.66,2.032,,93.01,OHH,-1.27367,0.221079,0.00559099,0.830504 kka2_1:2_P76E,kka2_1:2_76,Kka2,kka2_1:2,P00552,0.83051,NO,76,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.449,-2.905,1.456,,0.331,.,B,0.52,-0.41,0.345,,63.64,HOO,-1.662,0.295029,0.00625685,0.83051 beta-lactamase_0_P165R,beta-lactamase_0_165,TEM-1,beta-lactamase_0,P62593,0.83055,NO,165,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.373,-3.877,2.504,,0.203,T,A,0.52,-0.31,3.242,,73.78,AOA,-1.359,0.0500837,0.00549538,0.83055 beta-lactamase_0_L199H,beta-lactamase_0_199,TEM-1,beta-lactamase_0,P62593,0.830559,NO,199,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-2.942,-4.8,1.858,,0.832,H,A,0.55,0.42,10.85,10.85,77.62,PHH,-2.32933,0.0500837,0.0048649,0.830559 beta-lactamase_0_I125S,beta-lactamase_0_125,TEM-1,beta-lactamase_0,P62593,0.830568,NO,125,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.441,-2.843,1.402,,,H,A,0.48,-0.7,1.874,,63.29,HHP,-1.248,0.0500837,0.00383964,0.830568 kka2_1:2_D156E,kka2_1:2_156,Kka2,kka2_1:2,P00552,0.830569,NO,156,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.696,-2.041,0.345,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.295029,0.00926998,0.830569 kka2_1:2_H106Y,kka2_1:2_106,Kka2,kka2_1:2,P00552,0.830608,NO,106,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-3.13,-4.391,1.261,,1.065,.,a,0.17,-0.95,2.53,,71.59,PBH,-2.10433,0.295029,0.00730778,0.830608 gb1_T237A,gb1_237,gb1,gb1,P06654,0.830611,NO,237,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.736,-2.802,1.066,,,,,,,0.218,,11.83,BPH,-2.27833,0.177985,0.00275316,0.830611 Ubiquitin_D32K,Ubiquitin_32,Uba1,Ubiquitin,P0CG48,0.830645,NO,32,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.451,-3.421,1.97,4.96502,0.835,H,A,,1.4,,,,PAB,-1.47067,0.205827,0.000758819,0.830645 Ubiquitin_D58V,Ubiquitin_58,Uba1,Ubiquitin,P0CG48,0.830645,NO,58,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.622,-3.462,1.84,5.06391,0.457,G,A,,-0.54,,,,PAH,-1.60267,0.205827,0.000639847,0.830645 Ubiquitin_G35L,Ubiquitin_35,Uba1,Ubiquitin,P0CG48,0.830645,NO,35,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.171,-3.416,2.245,4.96213,0.713,,L,,0.2,,,,AOH,-1.314,0.205827,0.000648878,0.830645 Ubiquitin_K27T,Ubiquitin_27,Uba1,Ubiquitin,P0CG48,0.830645,NO,27,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.064,-3.447,2.383,4.77438,0.086,H,A,2.89,-0.74,2.662,,27.01,HBH,-1.42667,0.205827,0.000767556,0.830645 Ubiquitin_T12H,Ubiquitin_12,Uba1,Ubiquitin,P0CG48,0.830645,NO,12,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.288,-2.879,1.591,4.93973,0.417,E,B,0.8,0.12,2.762,,25.84,BPH,-1.39867,0.205827,0.000657544,0.830645 beta-lactamase_625_F228G,beta-lactamase_625_228,TEM-1,beta-lactamase_625,P62593,0.830692,NO,228,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-2.342,-3.572,1.23,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.213352,0.0046669,0.830692 Pab1_A185H,Pab1_185,Pab1,Pab1,P04147,0.830758,NO,185,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.702,-4.316,2.614,,,,,,,1.756,,63.26,AHH,-1.66167,0.175299,0.00144499,0.830758 beta-lactamase_2500_L160F,beta-lactamase_2500_160,TEM-1,beta-lactamase_2500,P62593,0.830785,NO,160,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.977,-3.681,2.704,,0.022,,B,0.55,-0.6,0.895,,44.41,BHA,-0.936,0.361275,0.00193775,0.830785 kka2_1:4_A64E,kka2_1:4_64,Kka2,kka2_1:4,P00552,0.830788,NO,64,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.496,-2.982,1.486,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.168804,0.00705578,0.830788 beta-lactamase_A230S,beta-lactamase_230,TEM-1,beta-lactamase,P62593,0.830812,NO,230,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.154,-2.48,1.326,4.54336,0.01,E,B,0.75,-1.17,1.97,,50,HHA,-1.079,0.221079,0.00516841,0.830812 beta-lactamase_P224T,beta-lactamase_224,TEM-1,beta-lactamase,P62593,0.830813,NO,224,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.893,-3.414,2.521,5.179,0.383,,B,0.99,-0.3,0.383,,74.48,HOH,-1.26433,0.221079,0.00189564,0.830813 beta-lactamase_L135F,beta-lactamase_135,TEM-1,beta-lactamase,P62593,0.830825,NO,135,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.002,-3.671,2.669,5.28497,0.117,H,A,1.07,-0.58,0.697,,43.71,PHH,-1.03767,0.221079,0.00244423,0.830825 beta-lactamase_Y103N,beta-lactamase_103,TEM-1,beta-lactamase,P62593,0.830842,NO,103,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-1.33,-2.825,1.495,5.71734,0.613,S,l,2.55,1.21,5.721,,63.29,AHP,-1.48767,0.221079,0.00443048,0.830842 kka2_1:2_L102R,kka2_1:2_102,Kka2,kka2_1:2,P00552,0.830854,NO,102,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.804,-3.959,3.155,,,T,A,1.59,-1.17,4.258,,42.42,AHH,-1.398,0.295029,0.00201332,0.830854 beta-lactamase_0_G85W,beta-lactamase_0_85,TEM-1,beta-lactamase_0,P62593,0.830925,NO,85,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.011,-5.288,4.277,,0.805,T,l,0.29,1.7,2.25,,63.64,HOP,-1.68733,0.0500837,0.00252173,0.830925 kka2_1:4_L241R,kka2_1:4_241,Kka2,kka2_1:4,P00552,0.830976,NO,241,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.158,-4.121,2.963,,0.08,H,A,0.55,-0.82,1.598,,63.26,HHH,-1.58533,0.168804,0.0117299,0.830976 beta-lactamase_625_E35M,beta-lactamase_625_35,TEM-1,beta-lactamase_625,P62593,0.830985,NO,35,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-0.869,-4.754,3.885,,0.15,H,A,1.04,0.21,0.664,,46.85,HAA,-1.88667,0.213352,0.00174441,0.830985 beta-lactamase_0_F70S,beta-lactamase_0_70,TEM-1,beta-lactamase_0,P62593,0.831022,NO,70,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.169,-2.713,1.544,,,H,A,0.58,-1.34,2.153,,63.99,PHB,-0.980667,0.0500837,0.00193499,0.831022 kka2_1:4_P109T,kka2_1:4_109,Kka2,kka2_1:4,P00552,0.831054,NO,109,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.412,-2.893,1.481,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.168804,0.0070929,0.831054 beta-lactamase_D161A,beta-lactamase_161,TEM-1,beta-lactamase,P62593,0.831059,NO,161,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.891,-3.235,2.344,5.12208,0.341,,A,0.23,-0.52,1.602,,61.19,HAB,-0.961333,0.221079,0.000897697,0.831059 beta-lactamase_0_S68D,beta-lactamase_0_68,TEM-1,beta-lactamase_0,P62593,0.831062,NO,68,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-0.913,-3.241,2.328,,0.064,G,A,0.27,-1.03,1.441,,64.69,HPP,-1.37233,0.0500837,0.000800065,0.831062 kka2_1:2_V83G,kka2_1:2_83,Kka2,kka2_1:2,P00552,0.831132,NO,83,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-2.567,-3.646,1.079,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.295029,0.00650486,0.831132 kka2_1:8_R239S,kka2_1:8_239,Kka2,kka2_1:8,P00552,0.831159,NO,239,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.949,-2.753,-0.196,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.100394,0.00835326,0.831159 kka2_1:8_R239S,kka2_1:8_239,Kka2,kka2_1:8,P00552,0.831159,NO,239,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.949,-2.753,-0.196,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.100394,0.00835326,0.831159 beta-lactamase_0_T198M,beta-lactamase_0_198,TEM-1,beta-lactamase_0,P62593,0.831196,NO,198,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.168,-4.608,2.44,,0.489,,B,0.22,-0.13,9.874,,73.78,HPH,-1.98767,0.0500837,0.004311,0.831196 beta-lactamase_0_P143N,beta-lactamase_0_143,TEM-1,beta-lactamase_0,P62593,0.831217,NO,143,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.967,-3.954,2.987,,0.075,H,A,0.52,-0.37,11.868,11.868,66.78,OOB,-1.354,0.0500837,0.00114551,0.831217 beta-lactamase_0_L136A,beta-lactamase_0_136,TEM-1,beta-lactamase_0,P62593,0.831278,NO,136,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.232,-3.144,1.912,,,H,A,0.55,-0.34,0.648,,48.95,HHH,-1.088,0.0500837,0.00442304,0.831278 beta-lactamase_I140F,beta-lactamase_140,TEM-1,beta-lactamase,P62593,0.831321,NO,140,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.733,-2.91,1.177,5.29918,0.128,H,A,1,0.41,1.16,,73.08,PHO,-1.48733,0.221079,0.00597777,0.831321 beta-lactamase_M209C,beta-lactamase_209,TEM-1,beta-lactamase,P62593,0.831321,NO,209,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.442,-4.758,3.316,5.44502,,H,A,1.75,-0.97,1.402,,64.69,HHA,-1.52633,0.221079,0.00625021,0.831321 beta-lactamase_S51V,beta-lactamase_51,TEM-1,beta-lactamase,P62593,0.831321,NO,51,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.526,-3.559,2.033,5.06164,0.496,T,A,0.25,0.26,1.699,,72.73,PPO,-1.88467,0.221079,0.00504821,0.831321 beta-lactamase_2500_T187M,beta-lactamase_2500_187,TEM-1,beta-lactamase_2500,P62593,0.83134,NO,187,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.401,-4.516,3.115,,0.007,H,A,0.22,-1.19,3.91,,67.48,PPH,-1.69633,0.361275,0.00491782,0.83134 WW_domain_N191S,WW_domain_191,Yap65,WW_domain,P46937,0.831359,NO,191,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-1.519,-1.886,0.367,5.96016,,,,,,5.117,,66.07,HPB,-1.554,0.153962,0.00270999,0.831359 beta-lactamase_0_M66Y,beta-lactamase_0_66,TEM-1,beta-lactamase_0,P62593,0.831366,NO,66,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.362,-4.034,2.672,,0.013,,A,0.55,-0.7,1.204,,73.08,OHH,-1.49567,0.0500837,0.00412876,0.831366 beta-lactamase_625_N130G,beta-lactamase_625_130,TEM-1,beta-lactamase_625,P62593,0.831398,NO,130,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-0.798,-2.908,2.11,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.213352,0.000683376,0.831398 kka2_1:4_G245N,kka2_1:4_245,Kka2,kka2_1:4,P00552,0.831417,NO,245,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.812,-2.694,1.882,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.168804,0.00683899,0.831417 kka2_1:8_D250G,kka2_1:8_250,Kka2,kka2_1:8,P00552,0.831434,NO,250,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.015,-3.27,2.255,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.100394,0.0177103,0.831434 kka2_1:8_D250G,kka2_1:8_250,Kka2,kka2_1:8,P00552,0.831434,NO,250,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.015,-3.27,2.255,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.100394,0.0177103,0.831434 beta-lactamase_0_A183Q,beta-lactamase_0_183,TEM-1,beta-lactamase_0,P62593,0.831455,NO,183,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.231,-3.932,2.701,,0.155,H,A,0.46,-0.91,1.48,,77.62,HHH,-1.53367,0.0500837,0.00296631,0.831455 beta-lactamase_L135A,beta-lactamase_135,TEM-1,beta-lactamase,P62593,0.83146,NO,135,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.002,-3.131,2.129,5.28497,0.117,H,A,1.07,-0.58,0.697,,43.71,PHH,-1.03767,0.221079,0.00244423,0.83146 beta-lactamase_0_V82N,beta-lactamase_0_82,TEM-1,beta-lactamase_0,P62593,0.831467,NO,82,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.325,-2.935,1.61,,0.267,H,A,0.44,0.08,1.893,,93.01,BHA,-1.28567,0.0500837,0.00397046,0.831467 kka2_1:4_S32G,kka2_1:4_32,Kka2,kka2_1:4,P00552,0.831468,NO,32,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-0.804,-2.936,2.132,,0.768,S,b,0.27,3.75,,,,OPA,-1.74533,0.168804,0.00149998,0.831468 kka2_1:1_A137I,kka2_1:1_137,Kka2,kka2_1:1,P00552,0.831485,NO,137,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.156,-2.375,0.219,,0.029,H,A,0.46,0.34,1.323,,63.26,PHB,-2.559,0.520039,0.00515054,0.831485 beta-lactamase_0_K286I,beta-lactamase_0_286,TEM-1,beta-lactamase_0,P62593,0.831498,NO,286,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.0500837,,0.831498 gb1_T243P,gb1_243,gb1,gb1,P06654,0.831531,NO,243,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.415,-3.466,2.051,,,,,,,1.083,,37.28,PPP,-1.43233,0.177985,0.00308687,0.831531 PSD95pdz3_A375V,PSD95pdz3_375,PSD95pdz3,PSD95pdz3,P31016,0.83154,NO,375,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.307,-2.76,1.453,5.05512,,,,,13.888,,,,PHH,-1.43767,0.0758425,0.000356809,0.83154 beta-lactamase_E195A,beta-lactamase_195,TEM-1,beta-lactamase,P62593,0.831582,NO,195,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.186,-2.778,0.592,7.28489,1.016,S,A,1.52,0.85,2.583,,77.62,OAH,-2.02,0.221079,0.00496565,0.831582 beta-lactamase_M184C,beta-lactamase_184,TEM-1,beta-lactamase,P62593,0.831582,NO,184,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.593,-4.787,3.194,5.39575,,H,A,1.3,-0.87,2.893,,62.94,HHH,-1.41,0.221079,0.00356019,0.831582 beta-lactamase_T116R,beta-lactamase_116,TEM-1,beta-lactamase,P62593,0.831582,NO,116,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.28,-2.627,1.347,4.78335,0.115,E,B,0.69,-0.12,0.343,,67.48,HPH,-1.39967,0.221079,0.00336175,0.831582 beta-lactamase_0_K254S,beta-lactamase_0_254,TEM-1,beta-lactamase_0,P62593,0.83161,NO,254,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-2.126,-3.446,1.32,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.0500837,0.00369,0.83161 kka2_1:1_R122W,kka2_1:1_122,Kka2,kka2_1:1,P00552,0.831647,NO,122,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.175,-5.581,3.406,,0.487,H,A,1.2,0.26,1.356,,71.59,BBH,-1.53833,0.520039,0.00736512,0.831647 beta-lactamase_G52K,beta-lactamase_52,TEM-1,beta-lactamase,P62593,0.831673,NO,52,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.149,-3.631,2.482,5.12093,0.299,,l,0.77,-0.04,2.103,,64.69,POB,-1.66267,0.221079,0.00340138,0.831673 beta-lactamase_2500_S221D,beta-lactamase_2500_221,TEM-1,beta-lactamase_2500,P62593,0.831716,NO,221,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.754,-3.645,1.891,,0.624,H,A,0.27,-0.2,1.971,,74.48,BPH,-1.59967,0.361275,0.0046094,0.831716 beta-lactamase_D99G,beta-lactamase_99,TEM-1,beta-lactamase,P62593,0.831726,NO,99,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.191,-3.32,2.129,5.66081,0.402,G,A,0.23,0.36,1.318,,64.69,PAH,-1.794,0.221079,0.00305446,0.831726 beta-lactamase_2500_L150T,beta-lactamase_2500_150,TEM-1,beta-lactamase_2500,P62593,0.831731,NO,150,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.326,-2.5,1.174,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.361275,0.00463171,0.831731 kka2_1:8_W236C,kka2_1:8_236,Kka2,kka2_1:8,P00552,0.831791,NO,236,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-1.363,-3.273,1.91,,0.303,H,A,1.51,-0.76,1.87,,48.48,AHH,-1.81267,0.100394,0.0088796,0.831791 kka2_1:8_W236C,kka2_1:8_236,Kka2,kka2_1:8,P00552,0.831791,NO,236,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-1.363,-3.273,1.91,,0.303,H,A,1.51,-0.76,1.87,,48.48,AHH,-1.81267,0.100394,0.0088796,0.831791 WW_domain_L173V,WW_domain_173,Yap65,WW_domain,P46937,0.831814,NO,173,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.117,-2.631,1.514,,,,,,,,,,OHO,-1.06233,0.153962,0.000851849,0.831814 kka2_1:2_A255T,kka2_1:2_255,Kka2,kka2_1:2,P00552,0.831873,NO,255,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.715,-3.017,1.302,,0.466,H,A,0.46,-0.52,5.144,,65.53,HHH,-1.71267,0.295029,0.0126809,0.831873 beta-lactamase_Y103G,beta-lactamase_103,TEM-1,beta-lactamase,P62593,0.831878,NO,103,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-1.33,-3.527,2.197,5.71734,0.613,S,l,2.55,1.21,5.721,,63.29,AHP,-1.48767,0.221079,0.00443048,0.831878 beta-lactamase_0_W227P,beta-lactamase_0_227,TEM-1,beta-lactamase_0,P62593,0.831882,NO,227,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-0.982,-4.323,3.341,,0.272,,B,0.47,-0.29,3.782,,74.48,OHH,-1.595,0.0500837,0.00226019,0.831882 kka2_1:8_T125P,kka2_1:8_125,Kka2,kka2_1:8,P00552,0.831928,NO,125,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.622,-3.993,1.371,,0.791,T,A,0.22,0.33,2.675,,92.05,BPH,-1.56933,0.100394,0.00821755,0.831928 kka2_1:8_T125P,kka2_1:8_125,Kka2,kka2_1:8,P00552,0.831928,NO,125,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.622,-3.993,1.371,,0.791,T,A,0.22,0.33,2.675,,92.05,BPH,-1.56933,0.100394,0.00821755,0.831928 beta-lactamase_0_G90K,beta-lactamase_0_90,TEM-1,beta-lactamase_0,P62593,0.831947,NO,90,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-2.091,-3.514,1.423,,0.598,T,A,0.29,0.32,2.04,,77.62,HOB,-1.52633,0.0500837,0.00490273,0.831947 beta-lactamase_0_L218P,beta-lactamase_0_218,TEM-1,beta-lactamase_0,P62593,0.831983,NO,218,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.391,-4.052,2.661,,,I,b,0.55,-0.53,28.707,28.707,74.48,OHH,-1.58867,0.0500837,0.00618274,0.831983 beta-lactamase_0_H151E,beta-lactamase_0_151,TEM-1,beta-lactamase_0,P62593,0.831984,NO,151,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-2.96,-3.258,0.298,,0.594,H,A,0.17,0.1,9.375,,77.62,HBP,-2.34767,0.0500837,0.00216946,0.831984 gb1_F256S,gb1_256,gb1,gb1,P06654,0.831989,NO,256,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.241,-3.388,2.147,,,,,,,,,,HHB,-2.04767,0.177985,0.00435993,0.831989 gb1_T251E,gb1_251,gb1,gb1,P06654,0.831989,NO,251,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.794,-1.828,0.034,,,,,,,3.514,3.514,37.28,HPH,-1.56067,0.177985,0.00232932,0.831989 beta-lactamase_G226F,beta-lactamase_226,TEM-1,beta-lactamase,P62593,0.832023,NO,226,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.461,-4.428,2.967,5.70682,0.701,T,l,0.77,-0.25,3.199,,74.48,HOH,-1.42933,0.221079,0.00665294,0.832023 WW_domain_A175C,WW_domain_175,Yap65,WW_domain,P46937,0.832181,NO,175,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.631,-4.67,3.039,6.69537,,,,,,6.257,,83.93,OHO,-1.30033,0.153962,0.00326874,0.832181 beta-lactamase_0_K53T,beta-lactamase_0_53,TEM-1,beta-lactamase_0,P62593,0.832183,NO,53,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-2.313,-2.702,0.389,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.0500837,0.00383383,0.832183 kka2_1:2_E142V,kka2_1:2_142,Kka2,kka2_1:2,P00552,0.8322,NO,142,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.221,-3.677,1.456,,0.471,H,A,1.52,0.85,3.693,,65.53,HAB,-2.08033,0.295029,0.00748883,0.8322 kka2_1:8_R38L,kka2_1:8_38,Kka2,kka2_1:8,P00552,0.832202,NO,38,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.207,-1.87,0.663,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.100394,0.00372499,0.832202 kka2_1:8_R38L,kka2_1:8_38,Kka2,kka2_1:8,P00552,0.832202,NO,38,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.207,-1.87,0.663,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.100394,0.00372499,0.832202 beta-lactamase_0_S104I,beta-lactamase_0_104,TEM-1,beta-lactamase_0,P62593,0.832353,NO,104,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.015,-3.786,2.771,,0.04,,b,0.27,0.57,1.148,,63.29,HPO,-1.05267,0.0500837,0.00218083,0.832353 beta-lactamase_0_V31S,beta-lactamase_0_31,TEM-1,beta-lactamase_0,P62593,0.832361,NO,31,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.822,-3.594,1.772,,,H,A,0.44,-0.46,4.126,,73.78,BHB,-2.03767,0.0500837,0.00478065,0.832361 kka2_1:1_G210Q,kka2_1:1_210,Kka2,kka2_1:1,P00552,0.832415,NO,210,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.095,-4.139,3.044,,0.103,T,A,0.29,-0.62,14.483,14.483,50,OOB,-0.966667,0.520039,0.00598378,0.832415 kka2_1:2_T73N,kka2_1:2_73,Kka2,kka2_1:2,P00552,0.832417,NO,73,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.51,-3.876,1.366,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.295029,0.00628605,0.832417 kka2_1:1_Q252K,kka2_1:1_252,Kka2,kka2_1:1,P00552,0.832418,NO,252,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.63,-2.767,0.137,,0.906,H,A,0.64,0.35,1.369,,92.05,PPB,-2.20733,0.520039,0.0121001,0.832418 kka2_1:4_Q27W,kka2_1:4_27,Kka2,kka2_1:4,P00552,0.832432,NO,27,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-1.659,-5.449,3.79,,0.608,,A,0.4,0.71,1.498,,65.53,PPP,-1.90733,0.168804,0.00595365,0.832432 kka2_1:4_W24Y,kka2_1:4_24,Kka2,kka2_1:4,P00552,0.832462,NO,24,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-1.779,-3.045,1.266,,0.477,E,B,1.51,-0.21,2.666,,56.06,AHH,-2.24467,0.168804,0.00631564,0.832462 beta-lactamase_G154H,beta-lactamase_154,TEM-1,beta-lactamase,P62593,0.832471,NO,154,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.823,-4.704,3.881,5.40944,0.54,T,l,0.77,-0.56,2.283,,64.69,HOA,-1.635,0.221079,0.00180205,0.832471 beta-lactamase_2500_L49T,beta-lactamase_2500_49,TEM-1,beta-lactamase_2500,P62593,0.832481,NO,49,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.897,-1.853,-0.044,,0.131,T,A,0.55,0.04,6.681,,64.69,AHP,-1.99233,0.361275,0.00401477,0.832481 beta-lactamase_L150S,beta-lactamase_150,TEM-1,beta-lactamase,P62593,0.832575,NO,150,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.326,-3.477,2.151,5.15566,,H,A,1.75,-0.2,1.615,,62.94,HHB,-1.86167,0.221079,0.00463171,0.832575 beta-lactamase_2500_P255R,beta-lactamase_2500_255,TEM-1,beta-lactamase_2500,P62593,0.832603,NO,255,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-2.266,-4.188,1.922,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.361275,0.00499612,0.832603 beta-lactamase_2500_F149H,beta-lactamase_2500_149,TEM-1,beta-lactamase_2500,P62593,0.832622,NO,149,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.299,-4.304,3.005,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.361275,0.00418462,0.832622 kka2_1:1_A166T,kka2_1:1_166,Kka2,kka2_1:1,P00552,0.832645,NO,166,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.407,-1.912,-0.495,,0.534,.,B,0.46,1.03,1.147,,71.59,HHO,-2.421,0.520039,0.00799912,0.832645 kka2_1:4_L184M,kka2_1:4_184,Kka2,kka2_1:4,P00552,0.832645,NO,184,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.496,-3.37,1.874,,0.489,E,B,1.59,-0.06,4.495,,63.26,AHH,-1.24833,0.168804,0.00518742,0.832645 beta-lactamase_L89V,beta-lactamase_89,TEM-1,beta-lactamase,P62593,0.83265,NO,89,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.096,-3.043,1.947,5.41092,0.168,T,A,1.75,0.63,1.599,,64.34,PHO,-1.75767,0.221079,0.00207068,0.83265 beta-lactamase_39_L219I,beta-lactamase_39_219,TEM-1,beta-lactamase_39,P62593,0.832666,NO,219,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.313,-1.692,0.379,,,I,A,0.55,-0.51,19.842,19.842,74.48,HHB,-1.21533,0.0495842,0.00664345,0.832666 kka2_1:4_D157T,kka2_1:4_157,Kka2,kka2_1:4,P00552,0.832683,NO,157,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.993,-3.488,2.495,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.168804,0.0042313,0.832683 WW_domain_M179W,WW_domain_179,Yap65,WW_domain,P46937,0.83269,NO,179,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.541,-4.649,3.108,6.54704,,,,,,,,,AHH,-1.31367,0.153962,0.00400164,0.83269 kka2_1:1_D159R,kka2_1:1_159,Kka2,kka2_1:1,P00552,0.832728,NO,159,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.82,-3.995,3.175,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.520039,0.0030485,0.832728 kka2_1:2_I2S,kka2_1:2_2,Kka2,kka2_1:2,P00552,0.83273,NO,2,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.787,-3.207,1.42,,,,,,,5.773,,71.59,HHA,-1.92433,0.295029,0.00246644,0.83273 beta-lactamase_0_S233L,beta-lactamase_0_233,TEM-1,beta-lactamase_0,P62593,0.832767,NO,233,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.886,-3.357,1.471,,0.016,E,B,0.27,-1.01,3.579,,77.62,BPO,-1.17267,0.0500837,0.00311415,0.832767 beta-lactamase_39_R162I,beta-lactamase_39_162,TEM-1,beta-lactamase_39,P62593,0.832792,NO,162,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.016,-3.867,2.851,,0.124,S,B,1.2,-0.37,31.656,31.656,64.69,ABH,-1.25,0.0495842,0.000561334,0.832792 beta-lactamase_0_G52A,beta-lactamase_0_52,TEM-1,beta-lactamase_0,P62593,0.832815,NO,52,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.149,-2.316,1.167,,0.299,,l,0.29,-0.04,1.164,,64.69,POB,-1.66267,0.0500837,0.00340138,0.832815 beta-lactamase_0_Q88I,beta-lactamase_0_88,TEM-1,beta-lactamase_0,P62593,0.832865,NO,88,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.086,-3.166,1.08,,0.807,,B,0.64,2.03,0.4,,77.62,APH,-1.53433,0.0500837,0.00504167,0.832865 kka2_1:4_T130P,kka2_1:4_130,Kka2,kka2_1:4,P00552,0.832896,NO,130,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.392,-4.046,1.654,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.168804,0.00804204,0.832896 beta-lactamase_2500_G52N,beta-lactamase_2500_52,TEM-1,beta-lactamase_2500,P62593,0.832922,NO,52,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.149,-3.58,2.431,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.361275,0.00340138,0.832922 beta-lactamase_0_V260T,beta-lactamase_0_260,TEM-1,beta-lactamase_0,P62593,0.832933,NO,260,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.0500837,0.00471757,0.832933 Pab1_I157R,Pab1_157,Pab1,Pab1,P04147,0.832987,NO,157,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.623,-4.046,2.423,,,,,,,1.439,,79.72,BHH,-1.28667,0.175299,0.0018103,0.832987 PSD95pdz3_G351P,PSD95pdz3_351,PSD95pdz3,PSD95pdz3,P31016,0.833029,NO,351,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.008,-3.561,2.553,5.44798,,,,,20.7625,,,,POA,-1.37133,0.0758425,0.000691282,0.833029 beta-lactamase_0_L223K,beta-lactamase_0_223,TEM-1,beta-lactamase_0,P62593,0.833061,NO,223,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.055,-3.742,2.687,,0.27,,B,0.55,0.09,1.633,,74.48,HHO,-1.35033,0.0500837,0.00372793,0.833061 beta-lactamase_A266I,beta-lactamase_266,TEM-1,beta-lactamase,P62593,0.833111,NO,266,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.369,-3.565,2.196,5.02057,0.175,S,B,0.52,0.07,1.832,,64.34,PHP,-2.08567,0.221079,0.0140785,0.833111 Pab1_L153C,Pab1_153,Pab1,Pab1,P04147,0.83316,NO,153,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.039,-4.454,3.415,,0.46,E,A,,-0.95,,,,HHP,-1.17667,0.175299,0.000321212,0.83316 beta-lactamase_0_T263R,beta-lactamase_0_263,TEM-1,beta-lactamase_0,P62593,0.833186,NO,263,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.0500837,0.0110582,0.833186 beta-lactamase_D161C,beta-lactamase_161,TEM-1,beta-lactamase,P62593,0.833277,NO,161,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.891,-5.1,4.209,5.12208,0.341,,A,0.23,-0.52,1.602,,61.19,HAB,-0.961333,0.221079,0.000897697,0.833277 kka2_1:4_D227H,kka2_1:4_227,Kka2,kka2_1:4,P00552,0.833373,NO,227,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.758,-4.528,2.77,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.168804,0.00745029,0.833373 kka2_1:4_R121C,kka2_1:4_121,Kka2,kka2_1:4,P00552,0.833375,NO,121,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.552,-5.157,3.605,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.168804,0.00523326,0.833375 beta-lactamase_2500_E195Y,beta-lactamase_2500_195,TEM-1,beta-lactamase_2500,P62593,0.833386,NO,195,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.186,-4.374,2.188,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.361275,0.00496565,0.833386 beta-lactamase_V214H,beta-lactamase_214,TEM-1,beta-lactamase,P62593,0.833387,NO,214,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.299,-4.922,3.623,5.74008,0.375,S,A,1.19,-0.44,1.899,,74.48,BHH,-1.53733,0.221079,0.00628442,0.833387 kka2_1:8_I115K,kka2_1:8_115,Kka2,kka2_1:8,P00552,0.833432,NO,115,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.606,-3.902,2.296,,0.105,H,A,1.52,-1.18,4.064,,65.53,PHH,-2.205,0.100394,0.00836567,0.833432 kka2_1:8_I115K,kka2_1:8_115,Kka2,kka2_1:8,P00552,0.833432,NO,115,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.606,-3.902,2.296,,0.105,H,A,1.52,-1.18,4.064,,65.53,PHH,-2.205,0.100394,0.00836567,0.833432 beta-lactamase_0_V78T,beta-lactamase_0_78,TEM-1,beta-lactamase_0,P62593,0.833445,NO,78,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.459,-3.492,2.033,,,H,A,0.44,-0.47,16.615,16.615,63.64,HHH,-1.17833,0.0500837,0.00492501,0.833445 kka2_1:8_L102R,kka2_1:8_102,Kka2,kka2_1:8,P00552,0.833486,NO,102,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.804,-3.959,3.155,,,T,A,1.59,-1.17,0.97,,42.42,AHH,-1.398,0.100394,0.00201332,0.833486 kka2_1:8_L102R,kka2_1:8_102,Kka2,kka2_1:8,P00552,0.833486,NO,102,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.804,-3.959,3.155,,,T,A,1.59,-1.17,0.97,,42.42,AHH,-1.398,0.100394,0.00201332,0.833486 beta-lactamase_K213W,beta-lactamase_213,TEM-1,beta-lactamase,P62593,0.833557,NO,213,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.81,-5.386,3.576,5.63167,0.67,,A,1.59,0.29,3.924,,67.83,ABH,-1.57767,0.221079,0.00610411,0.833557 kka2_1:1_G43D,kka2_1:1_43,Kka2,kka2_1:1,P00552,0.833572,NO,43,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.587,-2.025,0.438,,0.862,T,l,0.75,-0.67,2.247,,63.26,POB,-2.18533,0.520039,0.0071925,0.833572 beta-lactamase_0_T198P,beta-lactamase_0_198,TEM-1,beta-lactamase_0,P62593,0.833701,NO,198,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.168,-2.894,0.726,,0.489,,B,0.22,-0.13,9.874,,73.78,HPH,-1.98767,0.0500837,0.004311,0.833701 kka2_1:8_R217L,kka2_1:8_217,Kka2,kka2_1:8,P00552,0.833705,NO,217,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.158,-2.651,1.493,,0.252,T,A,0.16,-0.59,1.151,,52.27,ABH,-1.127,0.100394,0.0047191,0.833705 kka2_1:8_R217L,kka2_1:8_217,Kka2,kka2_1:8,P00552,0.833705,NO,217,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.158,-2.651,1.493,,0.252,T,A,0.16,-0.59,1.151,,52.27,ABH,-1.127,0.100394,0.0047191,0.833705 kka2_1:1_R145H,kka2_1:1_145,Kka2,kka2_1:1,P00552,0.833721,NO,145,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.804,-3.445,1.641,,0.346,H,A,1.2,1.23,23.699,23.699,63.64,HBP,-1.88033,0.520039,0.00846663,0.833721 beta-lactamase_39_Y95E,beta-lactamase_39_95,TEM-1,beta-lactamase_39,P62593,0.833755,NO,95,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-1.715,-3.911,2.196,,0.122,,b,0.21,-0.37,2.341,,77.62,BHP,-2.16167,0.0495842,0.00479449,0.833755 PSD95pdz3_V362G,PSD95pdz3_362,PSD95pdz3,PSD95pdz3,P31016,0.833777,NO,362,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.465,-3.265,1.8,4.99436,,,,,19.6443,,,,PHP,-1.46467,0.0758425,0.000538527,0.833777 beta-lactamase_0_T158P,beta-lactamase_0_158,TEM-1,beta-lactamase_0,P62593,0.83378,NO,158,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.116,-2.676,1.56,,0.036,,B,0.22,-0.85,1.041,,69.58,HPB,-1.269,0.0500837,0.00341825,0.83378 gb1_E282S,gb1_282,gb1,gb1,P06654,0.833807,NO,282,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.318,-2.034,0.716,,,,,,,1.075,,35.71,PAO,-1.573,0.177985,0.00209643,0.833807 beta-lactamase_0_L197V,beta-lactamase_0_197,TEM-1,beta-lactamase_0,P62593,0.833808,NO,197,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.853,-2.903,2.05,,0.007,S,B,0.55,0.33,1.087,,60.14,HHP,-1.833,0.0500837,0.00144602,0.833808 beta-lactamase_0_S266F,beta-lactamase_0_266,TEM-1,beta-lactamase_0,P62593,0.833843,NO,266,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.0500837,0.0140785,0.833843 kka2_1:4_V185R,kka2_1:4_185,Kka2,kka2_1:4,P00552,0.833856,NO,185,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.045,-4.178,3.133,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.168804,0.00367031,0.833856 beta-lactamase_T187F,beta-lactamase_187,TEM-1,beta-lactamase,P62593,0.833867,NO,187,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.401,-4.141,2.74,5.11453,0.007,H,A,0.3,-1.19,1.751,,67.48,PPH,-1.69633,0.221079,0.00491782,0.833867 beta-lactamase_A170E,beta-lactamase_170,TEM-1,beta-lactamase,P62593,0.833879,NO,170,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.237,-3.626,2.389,5.19261,0.126,,L,2.34,-0.35,2.427,,64.69,AHH,-1.63267,0.221079,0.00431903,0.833879 kka2_1:4_R258G,kka2_1:4_258,Kka2,kka2_1:4,P00552,0.833906,NO,258,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.626,-3.635,2.009,,0.316,H,A,1.2,-0.85,2.655,,53.03,HBH,-1.25933,0.168804,0.00983174,0.833906 kka2_1:4_A229I,kka2_1:4_229,Kka2,kka2_1:4,P00552,0.833962,NO,229,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.739,-3.861,2.122,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.168804,0.00942138,0.833962 kka2_1:8_V97G,kka2_1:8_97,Kka2,kka2_1:8,P00552,0.833977,NO,97,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.453,-3.796,2.343,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.100394,0.00737869,0.833977 kka2_1:8_V97G,kka2_1:8_97,Kka2,kka2_1:8,P00552,0.833977,NO,97,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.453,-3.796,2.343,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.100394,0.00737869,0.833977 Pab1_S155V,Pab1_155,Pab1,Pab1,P04147,0.83398,NO,155,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.039,-2.284,0.245,,,,,,,,,,PPB,-1.42267,0.175299,0.00208179,0.83398 beta-lactamase_0_N134S,beta-lactamase_0_134,TEM-1,beta-lactamase_0,P62593,0.834006,NO,134,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-0.879,-2.985,2.106,,0.138,H,A,0.61,-0.6,3.776,,53.15,HPH,-1.02233,0.0500837,0.000644786,0.834006 beta-lactamase_0_T116N,beta-lactamase_0_116,TEM-1,beta-lactamase_0,P62593,0.834072,NO,116,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.28,-2.515,1.235,,0.115,E,B,0.22,-0.12,1.356,,67.48,HPH,-1.39967,0.0500837,0.00336175,0.834072 kka2_1:2_V46M,kka2_1:2_46,Kka2,kka2_1:2,P00552,0.834078,NO,46,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-2.62,-3.643,1.023,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.295029,0.00631301,0.834078 beta-lactamase_2500_H110W,beta-lactamase_2500_110,TEM-1,beta-lactamase_2500,P62593,0.834126,NO,110,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-1.706,-5.185,3.479,,0.341,G,a,0.17,1.08,31.31,31.31,64.69,BBH,-1.73333,0.361275,0.00441499,0.834126 beta-lactamase_A266W,beta-lactamase_266,TEM-1,beta-lactamase,P62593,0.834134,NO,266,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.369,-5.397,4.028,5.02057,0.175,S,B,0.52,0.07,1.832,,64.34,PHP,-2.08567,0.221079,0.0140785,0.834134 beta-lactamase_0_W227A,beta-lactamase_0_227,TEM-1,beta-lactamase_0,P62593,0.834141,NO,227,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-0.982,-3.46,2.478,,0.272,,B,0.47,-0.29,3.782,,74.48,OHH,-1.595,0.0500837,0.00226019,0.834141 PSD95pdz3_S339D,PSD95pdz3_339,PSD95pdz3,PSD95pdz3,P31016,0.834176,NO,339,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.519,-2.925,1.406,5.34493,,,,,12.2167,,,,HPH,-1.55767,0.0758425,0.00084982,0.834176 beta-lactamase_2500_Q203W,beta-lactamase_2500_203,TEM-1,beta-lactamase_2500,P62593,0.834188,NO,203,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.168,-5.466,3.298,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.361275,0.00631514,0.834188 beta-lactamase_L111G,beta-lactamase_111,TEM-1,beta-lactamase,P62593,0.834195,NO,111,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.76,-3.666,1.906,5.8705,0.328,T,A,0.84,0.93,3.836,,64.34,BHP,-1.884,0.221079,0.00480671,0.834195 beta-lactamase_39_T264P,beta-lactamase_39_264,TEM-1,beta-lactamase_39,P62593,0.8342,NO,264,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.0495842,0.0119399,0.8342 Pab1_K166A,Pab1_166,Pab1,Pab1,P04147,0.834204,NO,166,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.262,-2.97,1.708,,0.299,,l,,0,,,,PBO,-1.21033,0.175299,0.0011038,0.834204 kka2_1:2_L60V,kka2_1:2_60,Kka2,kka2_1:2,P00552,0.834238,NO,60,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.997,-2.277,1.28,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.295029,0.00262176,0.834238 gb1_T237I,gb1_237,gb1,gb1,P06654,0.834258,NO,237,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.736,-3.68,1.944,,,,,,,0.218,,11.83,BPH,-2.27833,0.177985,0.00275316,0.834258 beta-lactamase_0_G234Q,beta-lactamase_0_234,TEM-1,beta-lactamase_0,P62593,0.834286,NO,234,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.62,-4.124,3.504,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.0500837,0.000889577,0.834286 beta-lactamase_625_L248A,beta-lactamase_625_248,TEM-1,beta-lactamase_625,P62593,0.834292,NO,248,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.213352,0.00428493,0.834292 beta-lactamase_F228L,beta-lactamase_228,TEM-1,beta-lactamase,P62593,0.834319,NO,228,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-2.342,-3.312,0.97,5.33448,0.154,E,B,1.1,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.221079,0.0046669,0.834319 beta-lactamase_I283S,beta-lactamase_283,TEM-1,beta-lactamase,P62593,0.834368,NO,283,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.638,-3.539,1.901,5.4178,0.165,H,A,1.23,0.04,1.576,,69.23,HHB,-1.735,0.221079,0.0429138,0.834368 beta-lactamase_0_R59Q,beta-lactamase_0_59,TEM-1,beta-lactamase_0,P62593,0.834431,NO,59,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.345,-2.612,1.267,,0.329,S,L,1.2,-0.09,2.919,,73.08,HBO,-2.24267,0.0500837,0.00318082,0.834431 kka2_1:4_A34T,kka2_1:4_34,Kka2,kka2_1:4,P00552,0.834441,NO,34,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.928,-3.197,2.269,,0.417,.,B,0.46,2.29,0.262,,52.27,AHH,-1.747,0.168804,0.00343484,0.834441 beta-lactamase_39_V42Q,beta-lactamase_39_42,TEM-1,beta-lactamase_39,P62593,0.834521,NO,42,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.564,-4.229,2.665,,0.017,E,B,0.44,-0.51,1.86,,63.99,BHO,-1.042,0.0495842,0.00404515,0.834521 PSD95pdz3_R318L,PSD95pdz3_318,PSD95pdz3,PSD95pdz3,P31016,0.834612,NO,318,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.582,-3.04,1.458,4.94876,,,,,17.5609,,,,BBO,-1.40567,0.0758425,0.00110471,0.834612 beta-lactamase_625_N274H,beta-lactamase_625_274,TEM-1,beta-lactamase_625,P62593,0.834636,NO,274,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.213352,0.0110418,0.834636 beta-lactamase_625_G281V,beta-lactamase_625_281,TEM-1,beta-lactamase_625,P62593,0.834706,NO,281,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.213352,0.0406482,0.834706 gb1_T244M,gb1_244,gb1,gb1,P06654,0.834708,NO,244,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.637,-4.041,2.404,,,,,,,0.202,,11.83,PPA,-1.92567,0.177985,0.00222755,0.834708 beta-lactamase_L160H,beta-lactamase_160,TEM-1,beta-lactamase,P62593,0.834714,NO,160,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.977,-4.948,3.971,5.32068,0.022,,B,1.75,-0.6,0.895,,44.41,BHA,-0.936,0.221079,0.00193775,0.834714 beta-lactamase_2500_M153H,beta-lactamase_2500_153,TEM-1,beta-lactamase_2500,P62593,0.834719,NO,153,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-3.193,-4.946,1.753,,0.14,T,A,0.55,-0.11,3.409,,77.62,PHO,-2.25767,0.361275,0.00509109,0.834719 Pab1_T145L,Pab1_145,Pab1,Pab1,P04147,0.834729,NO,145,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.067,-2.95,1.883,,0.237,H,A,0.3,0.69,,,,APH,-1.135,0.175299,0.000331088,0.834729 kka2_1:1_L70M,kka2_1:1_70,Kka2,kka2_1:1,P00552,0.834751,NO,70,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.017,-2.172,1.155,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.520039,0.00411884,0.834751 beta-lactamase_0_L74C,beta-lactamase_0_74,TEM-1,beta-lactamase_0,P62593,0.834799,NO,74,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.296,-4.647,3.351,,,H,A,0.55,-0.91,1.46,,50,HHO,-1.34933,0.0500837,0.00493255,0.834799 beta-lactamase_0_E166V,beta-lactamase_0_166,TEM-1,beta-lactamase_0,P62593,0.834897,NO,166,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.756,-2.896,1.14,,0.508,G,A,1.04,1.05,17.227,17.227,73.08,OAH,-1.42233,0.0500837,0.00512989,0.834897 beta-lactamase_F6E,beta-lactamase_6,TEM-1,beta-lactamase,P62593,0.834914,NO,6,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.847,-3.763,1.916,,,,,,,1.276,,67.83,BHB,-2.076,0.221079,0.00261627,0.834914 beta-lactamase_L111N,beta-lactamase_111,TEM-1,beta-lactamase,P62593,0.834914,NO,111,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.76,-4.132,2.372,5.8705,0.328,T,A,0.84,0.93,3.836,,64.34,BHP,-1.884,0.221079,0.00480671,0.834914 beta-lactamase_P217I,beta-lactamase_217,TEM-1,beta-lactamase,P62593,0.834914,NO,217,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-2.062,-4.071,2.009,5.19872,0.496,I,A,0.99,-0.33,0.431,,74.48,OOH,-1.64333,0.221079,0.00463211,0.834914 beta-lactamase_T116M,beta-lactamase_116,TEM-1,beta-lactamase,P62593,0.834914,NO,116,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.28,-4.634,3.354,4.78335,0.115,E,B,0.69,-0.12,0.343,,67.48,HPH,-1.39967,0.221079,0.00336175,0.834914 kka2_1:1_D183R,kka2_1:1_183,Kka2,kka2_1:1,P00552,0.835004,NO,183,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.204,-2.951,1.747,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.520039,0.00426304,0.835004 beta-lactamase_P249I,beta-lactamase_249,TEM-1,beta-lactamase,P62593,0.835035,NO,249,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.312,-3.815,2.503,5.10655,0.256,S,B,0.99,0.04,0.479,,72.73,OOA,-1.81367,0.221079,0.00220169,0.835035 beta-lactamase_R81V,beta-lactamase_81,TEM-1,beta-lactamase,P62593,0.835041,NO,81,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.466,-3.685,2.219,5.12166,0.218,H,A,0.68,1.66,1.236,,50,PBH,-1.60667,0.221079,0.00499763,0.835041 beta-lactamase_0_T147K,beta-lactamase_0_147,TEM-1,beta-lactamase_0,P62593,0.835045,NO,147,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.149,-3.536,2.387,,0.281,H,A,0.22,-0.68,3.487,,64.34,HPH,-1.456,0.0500837,0.00226017,0.835045 beta-lactamase_I45S,beta-lactamase_45,TEM-1,beta-lactamase,P62593,0.835108,NO,45,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-2.421,-2.717,0.296,5.31505,,E,B,1,-0.3,2.256,,77.62,HHA,-2.30267,0.221079,0.00452842,0.835108 beta-lactamase_0_D271H,beta-lactamase_0_271,TEM-1,beta-lactamase_0,P62593,0.835124,NO,271,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.0500837,0.00752082,0.835124 kka2_1:8_Y244H,kka2_1:8_244,Kka2,kka2_1:8,P00552,0.835174,NO,244,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-0.775,-3.808,3.033,,0.066,H,A,1.25,-0.64,,,,HHO,-1.41267,0.100394,0.00453187,0.835174 kka2_1:8_Y244H,kka2_1:8_244,Kka2,kka2_1:8,P00552,0.835174,NO,244,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-0.775,-3.808,3.033,,0.066,H,A,1.25,-0.64,,,,HHO,-1.41267,0.100394,0.00453187,0.835174 beta-lactamase_2500_M127S,beta-lactamase_2500_127,TEM-1,beta-lactamase_2500,P62593,0.835198,NO,127,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-2.251,-3.644,1.393,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.361275,0.00437927,0.835198 beta-lactamase_0_G141M,beta-lactamase_0_141,TEM-1,beta-lactamase_0,P62593,0.835206,NO,141,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.828,-4.966,4.138,,0.575,T,l,0.29,-0.28,0.722,,64.69,HOO,-1.08933,0.0500837,0.0012419,0.835206 kka2_1:2_E142G,kka2_1:2_142,Kka2,kka2_1:2,P00552,0.835208,NO,142,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.221,-2.713,0.492,,0.471,H,A,1.52,0.85,3.693,,65.53,HAB,-2.08033,0.295029,0.00748883,0.835208 kka2_1:8_D159G,kka2_1:8_159,Kka2,kka2_1:8,P00552,0.835228,NO,159,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.82,-2.148,1.328,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.100394,0.0030485,0.835228 kka2_1:8_D159G,kka2_1:8_159,Kka2,kka2_1:8,P00552,0.835228,NO,159,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.82,-2.148,1.328,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.100394,0.0030485,0.835228 beta-lactamase_625_P181T,beta-lactamase_625_181,TEM-1,beta-lactamase_625,P62593,0.835237,NO,181,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.813,-3.419,2.606,,,H,A,0.52,-1.14,1.797,,61.54,HOH,-1.795,0.213352,0.000703122,0.835237 beta-lactamase_0_A200K,beta-lactamase_0_200,TEM-1,beta-lactamase_0,P62593,0.835261,NO,200,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.878,-2.669,0.791,,0.757,H,A,0.46,-0.19,16.368,16.368,77.62,HHP,-2.001,0.0500837,0.0060056,0.835261 kka2_1:4_D101C,kka2_1:4_101,Kka2,kka2_1:4,P00552,0.835273,NO,101,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.028,-5.093,4.065,,0.213,E,B,0.75,-1.24,8.707,,63.64,PAH,-1.534,0.168804,0.00423361,0.835273 beta-lactamase_I243M,beta-lactamase_243,TEM-1,beta-lactamase,P62593,0.835295,NO,243,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.532,-4.364,2.832,5.26886,,E,B,1.68,-1.24,2.289,,50,OHH,-1.46867,0.221079,0.00464034,0.835295 beta-lactamase_156_I229S,beta-lactamase_156_229,TEM-1,beta-lactamase_156,P62593,0.835343,NO,229,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.267,-3.615,2.348,,0.083,E,B,0.48,-0.76,1.114,,50,HHH,-1.58767,0.111618,0.00477249,0.835343 beta-lactamase_0_R41V,beta-lactamase_0_41,TEM-1,beta-lactamase_0,P62593,0.835357,NO,41,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-0.942,-3.751,2.809,,0.321,E,B,1.2,-0.07,2.68,,65.03,HBH,-1.30267,0.0500837,0.00123327,0.835357 PSD95pdz3_I336N,PSD95pdz3_336,PSD95pdz3,PSD95pdz3,P31016,0.835378,NO,336,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.63,-3.805,2.175,5.11321,,,,,13.6363,,,,OHH,-1.38733,0.0758425,0.000887923,0.835378 beta-lactamase_0_E26I,beta-lactamase_0_26,TEM-1,beta-lactamase_0,P62593,0.835482,NO,26,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.454,-3.782,1.328,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.0500837,0.00297948,0.835482 beta-lactamase_0_L150S,beta-lactamase_0_150,TEM-1,beta-lactamase_0,P62593,0.835501,NO,150,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.326,-3.477,2.151,,,H,A,0.55,-0.2,2.128,,62.94,HHB,-1.86167,0.0500837,0.00463171,0.835501 beta-lactamase_625_V260S,beta-lactamase_625_260,TEM-1,beta-lactamase_625,P62593,0.835524,NO,260,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.213352,0.00471757,0.835524 Pab1_L153A,Pab1_153,Pab1,Pab1,P04147,0.83555,NO,153,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.039,-2.895,1.856,,0.46,E,A,,-0.95,,,,HHP,-1.17667,0.175299,0.000321212,0.83555 beta-lactamase_0_D252C,beta-lactamase_0_252,TEM-1,beta-lactamase_0,P62593,0.835556,NO,252,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.0500837,0.00575769,0.835556 beta-lactamase_F64Y,beta-lactamase_64,TEM-1,beta-lactamase,P62593,0.835557,NO,64,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-0.841,-3.037,2.196,5.70769,0.006,E,B,1.33,-0.95,,,,BHO,-0.892667,0.221079,0.000947691,0.835557 Pab1_L186Y,Pab1_186,Pab1,Pab1,P04147,0.835594,NO,186,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.783,-3.883,2.1,,,,,,,,,,HHP,-1.56967,0.175299,0.00154968,0.835594 kka2_1:8_R258G,kka2_1:8_258,Kka2,kka2_1:8,P00552,0.835607,NO,258,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.626,-3.635,2.009,,0.316,H,A,0.16,-0.85,5.58,,53.03,HBH,-1.25933,0.100394,0.00983174,0.835607 kka2_1:8_R258G,kka2_1:8_258,Kka2,kka2_1:8,P00552,0.835607,NO,258,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.626,-3.635,2.009,,0.316,H,A,0.16,-0.85,5.58,,53.03,HBH,-1.25933,0.100394,0.00983174,0.835607 kka2_1:8_P76W,kka2_1:8_76,Kka2,kka2_1:8,P00552,0.835635,NO,76,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.449,-5.603,4.154,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.100394,0.00625685,0.835635 kka2_1:8_P76W,kka2_1:8_76,Kka2,kka2_1:8,P00552,0.835635,NO,76,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.449,-5.603,4.154,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.100394,0.00625685,0.835635 beta-lactamase_0_N130M,beta-lactamase_0_130,TEM-1,beta-lactamase_0,P62593,0.835644,NO,130,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-0.798,-4.705,3.907,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.0500837,0.000683376,0.835644 kka2_1:2_A64E,kka2_1:2_64,Kka2,kka2_1:2,P00552,0.835658,NO,64,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.496,-2.982,1.486,,0.039,H,A,0.46,-0.57,14.509,14.509,56.06,AHH,-1.334,0.295029,0.00705578,0.835658 beta-lactamase_0_G240E,beta-lactamase_0_240,TEM-1,beta-lactamase_0,P62593,0.835672,NO,240,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.0500837,0.00591201,0.835672 WW_domain_Q195H,WW_domain_195,Yap65,WW_domain,P46937,0.835722,NO,195,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-1.839,-4.339,2.5,5.22735,,,,,,1.803,,70.04,APP,-1.719,0.153962,0.00394344,0.835722 kka2_1:4_V113T,kka2_1:4_113,Kka2,kka2_1:4,P00552,0.835742,NO,113,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.233,-3.45,2.217,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.168804,0.00650191,0.835742 beta-lactamase_I256C,beta-lactamase_256,TEM-1,beta-lactamase,P62593,0.835792,NO,256,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.621,-4.828,3.207,5.3196,,E,B,1,-0.84,1.615,,73.08,BHH,-1.80667,0.221079,0.00710634,0.835792 beta-lactamase_0_H287E,beta-lactamase_0_287,TEM-1,beta-lactamase_0,P62593,0.835813,NO,287,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,,,,,,,,,,,,,BBH,-1.111,0.0500837,,0.835813 beta-lactamase_A215T,beta-lactamase_215,TEM-1,beta-lactamase,P62593,0.835821,NO,215,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.503,-2.291,0.788,4.82164,,,a,0.75,-0.93,3.583,,74.48,HHO,-1.42633,0.221079,0.00544007,0.835821 beta-lactamase_0_N134I,beta-lactamase_0_134,TEM-1,beta-lactamase_0,P62593,0.835865,NO,134,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-0.879,-4.036,3.157,,0.138,H,A,0.61,-0.6,3.776,,53.15,HPH,-1.02233,0.0500837,0.000644786,0.835865 beta-lactamase_0_E119P,beta-lactamase_0_119,TEM-1,beta-lactamase_0,P62593,0.83589,NO,119,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.412,-3.828,2.416,,0.358,H,A,1.04,0.51,3.396,,63.99,BAH,-1.623,0.0500837,0.00386966,0.83589 kka2_1:4_G151V,kka2_1:4_151,Kka2,kka2_1:4,P00552,0.835926,NO,151,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.873,-3.846,2.973,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.168804,0.00339918,0.835926 beta-lactamase_P143S,beta-lactamase_143,TEM-1,beta-lactamase,P62593,0.835932,NO,143,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.967,-3.441,2.474,5.16366,0.075,H,A,0.99,-0.37,0.479,,66.78,OOB,-1.354,0.221079,0.00114551,0.835932 kka2_1:8_D118Y,kka2_1:8_118,Kka2,kka2_1:8,P00552,0.835987,NO,118,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.07,-4.383,2.313,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.100394,0.0067852,0.835987 kka2_1:8_D118Y,kka2_1:8_118,Kka2,kka2_1:8,P00552,0.835987,NO,118,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.07,-4.383,2.313,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.100394,0.0067852,0.835987 kka2_1:4_P179W,kka2_1:4_179,Kka2,kka2_1:4,P00552,0.836003,NO,179,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.974,-5.539,4.565,,0.113,,B,0.52,0.69,10.913,10.913,56.06,HOA,-2.19867,0.168804,0.00298346,0.836003 Pab1_K166N,Pab1_166,Pab1,Pab1,P04147,0.836022,NO,166,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.262,-3.341,2.079,,0.299,,l,,0,,,,PBO,-1.21033,0.175299,0.0011038,0.836022 beta-lactamase_L47F,beta-lactamase_47,TEM-1,beta-lactamase,P62593,0.836025,NO,47,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.876,-3.101,1.225,5.27297,0.007,E,B,1.07,0.2,1.244,,67.83,AHA,-1.639,0.221079,0.00439844,0.836025 beta-lactamase_P253E,beta-lactamase_253,TEM-1,beta-lactamase,P62593,0.836025,NO,253,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-2.253,-2.483,0.23,5.24842,0.308,,B,0.73,-0.46,2.293,,73.08,BOP,-2.10633,0.221079,0.00786358,0.836025 beta-lactamase_2500_H287L,beta-lactamase_2500_287,TEM-1,beta-lactamase_2500,P62593,0.836042,NO,287,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,,,,,,,,,,,,,BBH,-1.111,0.361275,,0.836042 PSD95pdz3_A376F,PSD95pdz3_376,PSD95pdz3,PSD95pdz3,P31016,0.836045,NO,376,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.307,-3.749,2.442,4.72134,,,,,17.108,,,,HHH,-1.49567,0.0758425,0.000341232,0.836045 PSD95pdz3_V328A,PSD95pdz3_328,PSD95pdz3,PSD95pdz3,P31016,0.836095,NO,328,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.465,-2.534,1.069,5.28275,,,,,16.8775,,,,HHO,-1.36767,0.0758425,0.000986706,0.836095 beta-lactamase_0_S266N,beta-lactamase_0_266,TEM-1,beta-lactamase_0,P62593,0.8361,NO,266,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.0500837,0.0140785,0.8361 kka2_1:1_D101A,kka2_1:1_101,Kka2,kka2_1:1,P00552,0.83617,NO,101,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.028,-2.654,1.626,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.520039,0.00423361,0.83617 beta-lactamase_0_D207I,beta-lactamase_0_207,TEM-1,beta-lactamase_0,P62593,0.83619,NO,207,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.064,-4.165,2.101,,0.409,H,A,0.75,0.12,5.277,,77.62,HAH,-1.77033,0.0500837,0.00592942,0.83619 kka2_1:1_G210C,kka2_1:1_210,Kka2,kka2_1:1,P00552,0.836248,NO,210,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.095,-2.875,1.78,,0.103,T,A,0.29,-0.62,14.483,14.483,50,OOB,-0.966667,0.520039,0.00598378,0.836248 beta-lactamase_0_K53Y,beta-lactamase_0_53,TEM-1,beta-lactamase_0,P62593,0.836313,NO,53,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-2.313,-4.187,1.874,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.0500837,0.00383383,0.836313 kka2_1:4_R145L,kka2_1:4_145,Kka2,kka2_1:4,P00552,0.836337,NO,145,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.804,-3.61,1.806,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.168804,0.00846663,0.836337 kka2_1:8_L94F,kka2_1:8_94,Kka2,kka2_1:8,P00552,0.836447,NO,94,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.618,-3.805,2.187,,0.058,E,B,1.59,-0.52,2.197,,56.06,HHO,-1.612,0.100394,0.00520888,0.836447 kka2_1:8_L94F,kka2_1:8_94,Kka2,kka2_1:8,P00552,0.836447,NO,94,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.618,-3.805,2.187,,0.058,E,B,1.59,-0.52,2.197,,56.06,HHO,-1.612,0.100394,0.00520888,0.836447 kka2_1:2_Q42Y,kka2_1:2_42,Kka2,kka2_1:2,P00552,0.83652,NO,42,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.907,-4.454,1.547,,1.044,T,B,0.64,-0.8,2.792,,71.59,HPO,-2.12433,0.295029,0.00679212,0.83652 beta-lactamase_0_H151A,beta-lactamase_0_151,TEM-1,beta-lactamase_0,P62593,0.836555,NO,151,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-2.96,-3.11,0.15,,0.594,H,A,0.17,0.1,9.375,,77.62,HBP,-2.34767,0.0500837,0.00216946,0.836555 beta-lactamase_S201R,beta-lactamase_201,TEM-1,beta-lactamase,P62593,0.836555,NO,201,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.183,-3.779,2.596,4.85496,0.064,H,A,0.77,-0.07,4.045,,64.69,HPB,-1.451,0.221079,0.00198815,0.836555 beta-lactamase_625_L73N,beta-lactamase_625_73,TEM-1,beta-lactamase_625,P62593,0.836607,NO,73,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.507,-4.234,2.727,,,H,A,0.55,-0.64,2.933,,67.83,HHH,-1.487,0.213352,0.00488983,0.836607 beta-lactamase_0_P60V,beta-lactamase_0_60,TEM-1,beta-lactamase_0,P62593,0.836717,NO,60,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-2.469,-3.507,1.038,,0.256,T,A,0.52,-0.56,3.653,,77.62,BOA,-1.97633,0.0500837,0.00521318,0.836717 PSD95pdz3_L379A,PSD95pdz3_379,PSD95pdz3,PSD95pdz3,P31016,0.836718,NO,379,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.347,-2.759,1.412,5.37777,,,,,16.8762,,,,HHB,-1.35667,0.0758425,0.00029733,0.836718 kka2_1:2_L92P,kka2_1:2_92,Kka2,kka2_1:2,P00552,0.836736,NO,92,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.893,-4.134,3.241,,0.007,E,B,1.59,-0.19,1.447,,63.26,HHH,-0.962,0.295029,0.00307177,0.836736 kka2_1:1_P98Q,kka2_1:1_98,Kka2,kka2_1:1,P00552,0.836755,NO,98,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.526,-3.169,1.643,,0.391,S,B,0.52,-0.65,1.521,,63.26,HOO,-1.19167,0.520039,0.00622754,0.836755 beta-lactamase_0_E35P,beta-lactamase_0_35,TEM-1,beta-lactamase_0,P62593,0.836799,NO,35,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-0.869,-3.68,2.811,,0.15,H,A,1.04,0.21,0.664,,46.85,HAA,-1.88667,0.0500837,0.00174441,0.836799 beta-lactamase_0_G240N,beta-lactamase_0_240,TEM-1,beta-lactamase_0,P62593,0.836846,NO,240,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.0500837,0.00591201,0.836846 beta-lactamase_M268K,beta-lactamase_268,TEM-1,beta-lactamase,P62593,0.836859,NO,268,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-2.023,-3.659,1.636,5.4797,0.471,H,A,0.09,0.3,1.071,,65.73,PHA,-2.16233,0.221079,0.0102525,0.836859 kka2_1:1_P167Q,kka2_1:1_167,Kka2,kka2_1:1,P00552,0.836885,NO,167,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-2.403,-4.147,1.744,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.520039,0.00543203,0.836885 beta-lactamase_0_Q97G,beta-lactamase_0_97,TEM-1,beta-lactamase_0,P62593,0.836923,NO,97,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.072,-2.827,0.755,,0.823,G,A,0.64,2.42,16.954,16.954,77.62,PPP,-2.43833,0.0500837,0.0045116,0.836923 beta-lactamase_0_W227H,beta-lactamase_0_227,TEM-1,beta-lactamase_0,P62593,0.836928,NO,227,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-0.982,-4.704,3.722,,0.272,,B,0.47,-0.29,3.782,,74.48,OHH,-1.595,0.0500837,0.00226019,0.836928 beta-lactamase_L38W,beta-lactamase_38,TEM-1,beta-lactamase,P62593,0.837,NO,38,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.343,-5.229,3.886,5.23728,0.088,H,A,1.75,0.2,1.986,,64.34,PHO,-1.78033,0.221079,0.00373244,0.837 beta-lactamase_0_L188F,beta-lactamase_0_188,TEM-1,beta-lactamase_0,P62593,0.837025,NO,188,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.166,-3.771,2.605,,,H,A,0.55,-0.3,2.739,,60.14,PHB,-1.47033,0.0500837,0.00295687,0.837025 beta-lactamase_E62I,beta-lactamase_62,TEM-1,beta-lactamase,P62593,0.83707,NO,62,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.193,-4.086,2.893,5.93066,0.342,S,B,1.52,-0.3,3.139,,73.08,AAB,-1.417,0.221079,0.00264802,0.83707 kka2_1:8_F37I,kka2_1:8_37,Kka2,kka2_1:8,P00552,0.837114,NO,37,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.427,-3.594,2.167,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.100394,0.00586193,0.837114 kka2_1:8_F37I,kka2_1:8_37,Kka2,kka2_1:8,P00552,0.837114,NO,37,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.427,-3.594,2.167,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.100394,0.00586193,0.837114 beta-lactamase_P105L,beta-lactamase_105,TEM-1,beta-lactamase,P62593,0.837142,NO,105,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.813,-3.581,2.768,5.08236,0.226,T,A,0.98,0.8,1.154,,63.29,POH,-1.01533,0.221079,0.0011981,0.837142 beta-lactamase_G216I,beta-lactamase_216,TEM-1,beta-lactamase,P62593,0.837176,NO,216,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.477,-4.183,2.706,4.91694,0.437,I,A,0.23,-0.58,1.718,,74.48,HOO,-1.68067,0.221079,0.00639568,0.837176 beta-lactamase_R81I,beta-lactamase_81,TEM-1,beta-lactamase,P62593,0.837176,NO,81,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.466,-4.004,2.538,5.12166,0.218,H,A,0.68,1.66,1.236,,50,PBH,-1.60667,0.221079,0.00499763,0.837176 kka2_1:2_I29N,kka2_1:2_29,Kka2,kka2_1:2,P00552,0.837278,NO,29,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.692,-3.146,1.454,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.295029,0.00619521,0.837278 beta-lactamase_2500_P255K,beta-lactamase_2500_255,TEM-1,beta-lactamase_2500,P62593,0.837289,NO,255,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.361275,0.00499612,0.837289 beta-lactamase_0_H287A,beta-lactamase_0_287,TEM-1,beta-lactamase_0,P62593,0.837293,NO,287,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,,,,,,,,,,,,,BBH,-1.111,0.0500837,,0.837293 kka2_1:2_V84L,kka2_1:2_84,Kka2,kka2_1:2,P00552,0.837335,NO,84,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-2.279,-2.527,0.248,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.295029,0.00724019,0.837335 beta-lactamase_0_T198Q,beta-lactamase_0_198,TEM-1,beta-lactamase_0,P62593,0.837371,NO,198,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.168,-2.734,0.566,,0.489,,B,0.22,-0.13,9.874,,73.78,HPH,-1.98767,0.0500837,0.004311,0.837371 gb1_T237L,gb1_237,gb1,gb1,P06654,0.837383,NO,237,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.736,-3.253,1.517,,,,,,,0.218,,11.83,BPH,-2.27833,0.177985,0.00275316,0.837383 beta-lactamase_0_A170F,beta-lactamase_0_170,TEM-1,beta-lactamase_0,P62593,0.837427,NO,170,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.237,-2.633,1.396,,0.126,,L,0.46,-0.35,2.427,,64.69,AHH,-1.63267,0.0500837,0.00431903,0.837427 beta-lactamase_2500_P255V,beta-lactamase_2500_255,TEM-1,beta-lactamase_2500,P62593,0.837445,NO,255,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.361275,0.00499612,0.837445 kka2_1:1_E149N,kka2_1:1_149,Kka2,kka2_1:1,P00552,0.837497,NO,149,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.994,-2.918,0.924,,0.674,H,A,1.04,1.63,3.671,,71.59,HAH,-1.59667,0.520039,0.00803343,0.837497 kka2_1:2_W24R,kka2_1:2_24,Kka2,kka2_1:2,P00552,0.837652,NO,24,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-1.779,-4.308,2.529,,0.477,E,B,1.51,-0.21,2.666,,56.06,AHH,-2.24467,0.295029,0.00631564,0.837652 beta-lactamase_2500_A34I,beta-lactamase_2500_34,TEM-1,beta-lactamase_2500,P62593,0.837654,NO,34,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.059,-2.06,0.001,,,H,A,0.46,-0.54,2.921,,73.78,AHA,-1.74967,0.361275,0.00407913,0.837654 beta-lactamase_T139W,beta-lactamase_139,TEM-1,beta-lactamase,P62593,0.837656,NO,139,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.901,-5.432,3.531,5.69095,0.216,H,A,0.3,0.39,2.256,,77.62,PPH,-2.04667,0.221079,0.00441837,0.837656 beta-lactamase_39_I206P,beta-lactamase_39_206,TEM-1,beta-lactamase_39,P62593,0.837711,NO,206,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-2.429,-4.04,1.611,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.0495842,0.00528934,0.837711 kka2_1:1_A64S,kka2_1:1_64,Kka2,kka2_1:1,P00552,0.837734,NO,64,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.496,-3.437,1.941,,0.039,H,A,0.46,-0.57,1.175,,56.06,AHH,-1.334,0.520039,0.00705578,0.837734 beta-lactamase_R81G,beta-lactamase_81,TEM-1,beta-lactamase,P62593,0.837753,NO,81,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.466,-2.66,1.194,5.12166,0.218,H,A,0.68,1.66,1.236,,50,PBH,-1.60667,0.221079,0.00499763,0.837753 kka2_1:4_E142F,kka2_1:4_142,Kka2,kka2_1:4,P00552,0.837761,NO,142,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.221,-4.452,2.231,,0.471,H,A,1.52,0.85,3.693,,65.53,HAB,-2.08033,0.168804,0.00748883,0.837761 beta-lactamase_0_T107C,beta-lactamase_0_107,TEM-1,beta-lactamase_0,P62593,0.837768,NO,107,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.117,-4.664,3.547,,,G,A,0.22,-0.06,3.73,,67.83,HPA,-1.265,0.0500837,0.00239347,0.837768 kka2_1:8_T51F,kka2_1:8_51,Kka2,kka2_1:8,P00552,0.8378,NO,51,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.199,-4.265,2.066,,0.05,E,B,0.82,-0.05,5.399,,63.64,BPA,-1.76767,0.100394,0.00628861,0.8378 kka2_1:8_T51F,kka2_1:8_51,Kka2,kka2_1:8,P00552,0.8378,NO,51,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.199,-4.265,2.066,,0.05,E,B,0.82,-0.05,5.399,,63.64,BPA,-1.76767,0.100394,0.00628861,0.8378 beta-lactamase_2500_A211F,beta-lactamase_2500_211,TEM-1,beta-lactamase_2500,P62593,0.837868,NO,211,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.896,-4.364,2.468,,0.369,T,A,0.46,-0.69,2.061,,77.62,AHA,-1.94633,0.361275,0.00648183,0.837868 beta-lactamase_0_P65I,beta-lactamase_0_65,TEM-1,beta-lactamase_0,P62593,0.837877,NO,65,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.894,-3.716,2.822,,0.098,E,B,0.52,-0.62,0.663,,40.56,HOH,-1.03233,0.0500837,0.00152776,0.837877 Pab1_T159K,Pab1_159,Pab1,Pab1,P04147,0.837951,NO,159,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.445,-3.397,1.952,,,,,,,2.531,,79.03,HPA,-1.19467,0.175299,0.00133849,0.837951 beta-lactamase_156_A235Y,beta-lactamase_156_235,TEM-1,beta-lactamase_156,P62593,0.837986,NO,235,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.266,-4.294,3.028,,0.32,E,B,0.46,-0.86,1.344,,50,OHO,-0.89,0.111618,0.00493474,0.837986 beta-lactamase_V82K,beta-lactamase_82,TEM-1,beta-lactamase,P62593,0.837987,NO,82,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.325,-3.754,2.429,5.27777,0.267,H,A,0.96,0.08,1.379,,93.01,BHA,-1.28567,0.221079,0.00397046,0.837987 beta-lactamase_0_G249W,beta-lactamase_0_249,TEM-1,beta-lactamase_0,P62593,0.837989,NO,249,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.0500837,0.00220169,0.837989 kka2_1:2_G245C,kka2_1:2_245,Kka2,kka2_1:2,P00552,0.83801,NO,245,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.812,-5.118,4.306,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.295029,0.00683899,0.83801 kka2_1:8_M148I,kka2_1:8_148,Kka2,kka2_1:8,P00552,0.838038,NO,148,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.847,-2.616,0.769,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.100394,0.00982664,0.838038 kka2_1:8_M148I,kka2_1:8_148,Kka2,kka2_1:8,P00552,0.838038,NO,148,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.847,-2.616,0.769,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.100394,0.00982664,0.838038 beta-lactamase_R162C,beta-lactamase_162,TEM-1,beta-lactamase,P62593,0.838042,NO,162,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.016,-5.08,4.064,5.34456,0.124,S,B,0.68,-0.37,31.656,31.656,64.69,ABH,-1.25,0.221079,0.000561334,0.838042 beta-lactamase_0_Q276L,beta-lactamase_0_276,TEM-1,beta-lactamase_0,P62593,0.838043,NO,276,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.0500837,0.0191712,0.838043 kka2_1:4_A255F,kka2_1:4_255,Kka2,kka2_1:4,P00552,0.83807,NO,255,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.715,-3.34,1.625,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.168804,0.0126809,0.83807 kka2_1:4_D82H,kka2_1:4_82,Kka2,kka2_1:4,P00552,0.838104,NO,82,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.946,-4.75,2.804,,0.341,E,b,0.75,0.52,11.923,11.923,63.64,HAH,-1.98,0.168804,0.00637516,0.838104 beta-lactamase_L74T,beta-lactamase_74,TEM-1,beta-lactamase,P62593,0.838106,NO,74,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.296,-3.432,2.136,5.50288,,H,A,1.75,-0.91,1.581,,50,HHO,-1.34933,0.221079,0.00493255,0.838106 beta-lactamase_I93Y,beta-lactamase_93,TEM-1,beta-lactamase,P62593,0.838112,NO,93,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.401,-4.112,2.711,5.74695,0.128,E,B,0.77,0.44,1.757,,67.83,BHB,-1.873,0.221079,0.00527066,0.838112 beta-lactamase_L38Q,beta-lactamase_38,TEM-1,beta-lactamase,P62593,0.838129,NO,38,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.343,-4.155,2.812,5.23728,0.088,H,A,1.75,0.2,1.986,,64.34,PHO,-1.78033,0.221079,0.00373244,0.838129 beta-lactamase_0_G114P,beta-lactamase_0_114,TEM-1,beta-lactamase_0,P62593,0.838154,NO,114,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.094,-3.918,2.824,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.0500837,0.00224919,0.838154 beta-lactamase_0_T116P,beta-lactamase_0_116,TEM-1,beta-lactamase_0,P62593,0.838195,NO,116,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.28,-3.831,2.551,,0.115,E,B,0.22,-0.12,1.356,,67.48,HPH,-1.39967,0.0500837,0.00336175,0.838195 beta-lactamase_0_T27F,beta-lactamase_0_27,TEM-1,beta-lactamase_0,P62593,0.838208,NO,27,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.905,-2.968,1.063,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.0500837,0.00306559,0.838208 beta-lactamase_0_N274L,beta-lactamase_0_274,TEM-1,beta-lactamase_0,P62593,0.838259,NO,274,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.0500837,0.0110418,0.838259 kka2_1:1_M178V,kka2_1:1_178,Kka2,kka2_1:1,P00552,0.83831,NO,178,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-3.206,-2.808,-0.398,,0.554,.,b,0.55,0.68,3.152,,71.59,BHO,-2.154,0.520039,0.00717253,0.83831 kka2_1:2_S104Q,kka2_1:2_104,Kka2,kka2_1:2,P00552,0.83843,NO,104,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.436,-3.082,1.646,,0.536,T,A,0.27,-1.11,5.49,,63.64,HPP,-1.91433,0.295029,0.00555207,0.83843 beta-lactamase_D161V,beta-lactamase_161,TEM-1,beta-lactamase,P62593,0.838456,NO,161,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.891,-3.753,2.862,5.12208,0.341,,A,0.23,-0.52,1.602,,61.19,HAB,-0.961333,0.221079,0.000897697,0.838456 beta-lactamase_D99C,beta-lactamase_99,TEM-1,beta-lactamase,P62593,0.838461,NO,99,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.191,-5.117,3.926,5.66081,0.402,G,A,0.23,0.36,1.318,,64.69,PAH,-1.794,0.221079,0.00305446,0.838461 beta-lactamase_D161T,beta-lactamase_161,TEM-1,beta-lactamase,P62593,0.838469,NO,161,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.891,-3.414,2.523,5.12208,0.341,,A,0.23,-0.52,1.602,,61.19,HAB,-0.961333,0.221079,0.000897697,0.838469 beta-lactamase_625_R81D,beta-lactamase_625_81,TEM-1,beta-lactamase_625,P62593,0.838471,NO,81,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.466,-3.611,2.145,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.213352,0.00499763,0.838471 kka2_1:4_G245C,kka2_1:4_245,Kka2,kka2_1:4,P00552,0.838557,NO,245,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.812,-5.118,4.306,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.168804,0.00683899,0.838557 beta-lactamase_0_L199V,beta-lactamase_0_199,TEM-1,beta-lactamase_0,P62593,0.838558,NO,199,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-2.942,-2.773,-0.169,,0.832,H,A,0.55,0.42,10.85,10.85,77.62,PHH,-2.32933,0.0500837,0.0048649,0.838558 beta-lactamase_0_T193V,beta-lactamase_0_193,TEM-1,beta-lactamase_0,P62593,0.838563,NO,193,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.914,-2.673,0.759,,0.439,H,a,0.22,0.33,11.546,11.546,63.99,HPO,-1.52133,0.0500837,0.00482669,0.838563 beta-lactamase_0_M66E,beta-lactamase_0_66,TEM-1,beta-lactamase_0,P62593,0.838581,NO,66,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.362,-3.832,2.47,,0.013,,A,0.55,-0.7,1.204,,73.08,OHH,-1.49567,0.0500837,0.00412876,0.838581 beta-lactamase_2500_I206N,beta-lactamase_2500_206,TEM-1,beta-lactamase_2500,P62593,0.838623,NO,206,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-2.429,-3.933,1.504,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.361275,0.00528934,0.838623 kka2_1:8_I115D,kka2_1:8_115,Kka2,kka2_1:8,P00552,0.838683,NO,115,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.606,-4.12,2.514,,0.105,H,A,1.52,-1.18,4.064,,65.53,PHH,-2.205,0.100394,0.00836567,0.838683 kka2_1:8_I115D,kka2_1:8_115,Kka2,kka2_1:8,P00552,0.838683,NO,115,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.606,-4.12,2.514,,0.105,H,A,1.52,-1.18,4.064,,65.53,PHH,-2.205,0.100394,0.00836567,0.838683 Ubiquitin_A28F,Ubiquitin_28,Uba1,Ubiquitin,P0CG48,0.83871,NO,28,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.895,-4.334,2.439,4.73736,0.369,H,A,,-0.11,,,,BHB,-1.47667,0.205827,0.000842053,0.83871 Ubiquitin_G35E,Ubiquitin_35,Uba1,Ubiquitin,P0CG48,0.83871,NO,35,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.171,-2.439,1.268,4.96213,0.713,,L,,0.2,,,,AOH,-1.314,0.205827,0.000648878,0.83871 Ubiquitin_G35F,Ubiquitin_35,Uba1,Ubiquitin,P0CG48,0.83871,NO,35,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.171,-4.029,2.858,4.96213,0.713,,L,,0.2,,,,AOH,-1.314,0.205827,0.000648878,0.83871 Ubiquitin_I13Q,Ubiquitin_13,Uba1,Ubiquitin,P0CG48,0.83871,NO,13,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.554,-4.199,2.645,5.19411,0.038,E,B,,-0.2,,,,PHP,-1.48,0.205827,0.000716423,0.83871 Ubiquitin_I36T,Ubiquitin_36,Uba1,Ubiquitin,P0CG48,0.83871,NO,36,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.477,-2.571,1.094,5.1035,0.203,,B,0.27,-0.22,1.552,,30.8,OHO,-1.30767,0.205827,0.000630555,0.83871 Ubiquitin_I3A,Ubiquitin_3,Uba1,Ubiquitin,P0CG48,0.83871,NO,3,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.402,-3.089,1.687,4.80819,,E,B,,-0.78,,,,PHH,-1.54533,0.205827,0.000836911,0.83871 Ubiquitin_K6Y,Ubiquitin_6,Uba1,Ubiquitin,P0CG48,0.83871,NO,6,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.093,-4.176,3.083,4.84211,0.35,E,B,1.82,-0.62,1.502,,71.82,HBP,-1.36133,0.205827,0.000784795,0.83871 Ubiquitin_N60I,Ubiquitin_60,Uba1,Ubiquitin,P0CG48,0.83871,NO,60,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-1.775,-3.07,1.295,5.00332,0.775,T,L,,0.33,,,,HPH,-1.532,0.205827,0.000814061,0.83871 Ubiquitin_Q41V,Ubiquitin_41,Uba1,Ubiquitin,P0CG48,0.83871,NO,41,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-1.329,-3.486,2.157,4.9201,0.017,E,B,0.12,-0.98,0.812,,30.07,PPB,-1.55067,0.205827,0.000521668,0.83871 Ubiquitin_S65K,Ubiquitin_65,Uba1,Ubiquitin,P0CG48,0.83871,NO,65,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.535,-3.473,1.938,4.99442,0.168,,b,0.25,-0.68,16.756,16.756,33.87,APP,-1.626,0.205827,0.000546776,0.83871 Ubiquitin_S65W,Ubiquitin_65,Uba1,Ubiquitin,P0CG48,0.83871,NO,65,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.535,-5.341,3.806,4.99442,0.168,,b,0.25,-0.68,16.756,16.756,33.87,APP,-1.626,0.205827,0.000546776,0.83871 beta-lactamase_0_D207R,beta-lactamase_0_207,TEM-1,beta-lactamase_0,P62593,0.838734,NO,207,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.064,-2.841,0.777,,0.409,H,A,0.75,0.12,5.277,,77.62,HAH,-1.77033,0.0500837,0.00592942,0.838734 beta-lactamase_39_L219Y,beta-lactamase_39_219,TEM-1,beta-lactamase_39,P62593,0.838751,NO,219,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.313,-3.958,2.645,,,I,A,0.55,-0.51,19.842,19.842,74.48,HHB,-1.21533,0.0495842,0.00664345,0.838751 beta-lactamase_0_Y95R,beta-lactamase_0_95,TEM-1,beta-lactamase_0,P62593,0.838766,NO,95,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-1.715,-4.186,2.471,,0.122,,b,0.21,-0.37,2.914,,77.62,BHP,-2.16167,0.0500837,0.00479449,0.838766 beta-lactamase_2500_G154Q,beta-lactamase_2500_154,TEM-1,beta-lactamase_2500,P62593,0.838841,NO,154,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.823,-4.083,3.26,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.361275,0.00180205,0.838841 beta-lactamase_156_N274M,beta-lactamase_156_274,TEM-1,beta-lactamase_156,P62593,0.838856,NO,274,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.111618,0.0110418,0.838856 WW_domain_L173F,WW_domain_173,Yap65,WW_domain,P46937,0.838874,NO,173,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.117,-3.394,2.277,,,,,,,,,,OHO,-1.06233,0.153962,0.000851849,0.838874 beta-lactamase_0_L79V,beta-lactamase_0_79,TEM-1,beta-lactamase_0,P62593,0.838893,NO,79,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.842,-2.879,2.037,,0.007,H,A,0.55,-0.16,5.053,,50.35,HHP,-1.44333,0.0500837,0.000947397,0.838893 kka2_1:8_F240C,kka2_1:8_240,Kka2,kka2_1:8,P00552,0.838898,NO,240,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-0.911,-4.889,3.978,,,H,A,1.62,-1.21,0.697,,50.38,BHH,-1.67267,0.100394,0.00552543,0.838898 kka2_1:8_F240C,kka2_1:8_240,Kka2,kka2_1:8,P00552,0.838898,NO,240,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-0.911,-4.889,3.978,,,H,A,1.62,-1.21,0.697,,50.38,BHH,-1.67267,0.100394,0.00552543,0.838898 kka2_1:2_P45T,kka2_1:2_45,Kka2,kka2_1:2,P00552,0.838933,NO,45,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.774,-2.639,0.865,,0.669,,B,0.52,-0.76,4.882,,71.59,BOH,-2.152,0.295029,0.00590481,0.838933 beta-lactamase_0_V101K,beta-lactamase_0_101,TEM-1,beta-lactamase_0,P62593,0.838937,NO,101,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.295,-3.742,2.447,,0.342,,B,0.44,0,1.61,,73.08,HHA,-1.54367,0.0500837,0.00374492,0.838937 beta-lactamase_A23C,beta-lactamase_23,TEM-1,beta-lactamase,P62593,0.838986,NO,23,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.548,-2.98,1.432,,,,,,,0.801,,93.01,HHB,-2.235,0.221079,0.00245563,0.838986 beta-lactamase_A34Y,beta-lactamase_34,TEM-1,beta-lactamase,P62593,0.838986,NO,34,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.059,-4.077,2.018,4.9129,,H,A,0.75,-0.54,3.614,,73.78,AHA,-1.74967,0.221079,0.00407913,0.838986 beta-lactamase_A77W,beta-lactamase_77,TEM-1,beta-lactamase,P62593,0.838986,NO,77,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.234,-5.367,4.133,4.75777,0.039,H,A,0.52,-0.56,1.708,,64.34,OHH,-1.294,0.221079,0.00282362,0.838986 beta-lactamase_E62K,beta-lactamase_62,TEM-1,beta-lactamase,P62593,0.838986,NO,62,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.193,-3.246,2.053,5.93066,0.342,S,B,1.52,-0.3,3.139,,73.08,AAB,-1.417,0.221079,0.00264802,0.838986 beta-lactamase_G263E,beta-lactamase_263,TEM-1,beta-lactamase,P62593,0.838986,NO,263,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-2.031,-1.876,-0.155,5.09799,0.517,S,l,0.77,0.31,16.425,16.425,77.62,POP,-1.78267,0.221079,0.0110582,0.838986 beta-lactamase_Q204W,beta-lactamase_204,TEM-1,beta-lactamase,P62593,0.838986,NO,204,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-1.382,-5.303,3.921,5.46394,0.204,H,A,0.12,0.09,1.707,,66.08,PPH,-1.49067,0.221079,0.00364106,0.838986 beta-lactamase_R271D,beta-lactamase_271,TEM-1,beta-lactamase,P62593,0.838986,NO,271,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.249,-3.747,2.498,5.24516,0.085,H,A,1.67,-0.05,0.474,,63.99,ABP,-1.36633,0.221079,0.00752082,0.838986 beta-lactamase_R63F,beta-lactamase_63,TEM-1,beta-lactamase,P62593,0.838986,NO,63,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-0.943,-4.214,3.271,5.49979,0.218,,B,0.45,-0.31,0.677,,44.06,ABH,-0.992333,0.221079,0.00126938,0.838986 beta-lactamase_T139F,beta-lactamase_139,TEM-1,beta-lactamase,P62593,0.838986,NO,139,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.901,-4.292,2.391,5.69095,0.216,H,A,0.3,0.39,2.256,,77.62,PPH,-2.04667,0.221079,0.00441837,0.838986 beta-lactamase_T27M,beta-lactamase_27,TEM-1,beta-lactamase,P62593,0.838986,NO,27,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.905,-4.581,2.676,5.39752,0.007,H,A,0.69,-0.37,0.745,,93.01,APH,-1.97933,0.221079,0.00306559,0.838986 beta-lactamase_M66T,beta-lactamase_66,TEM-1,beta-lactamase,P62593,0.839098,NO,66,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.362,-3.498,2.136,5.29561,0.013,,A,1.3,-0.7,1.319,,73.08,OHH,-1.49567,0.221079,0.00412876,0.839098 beta-lactamase_0_E166C,beta-lactamase_0_166,TEM-1,beta-lactamase_0,P62593,0.839139,NO,166,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.756,-5.069,3.313,,0.508,G,A,1.04,1.05,17.227,17.227,73.08,OAH,-1.42233,0.0500837,0.00512989,0.839139 gb1_L231M,gb1_231,gb1,gb1,P06654,0.839142,NO,231,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.603,-3.897,2.294,,,,,,,0.219,,11.83,BHH,-1.82633,0.177985,0.00322797,0.839142 beta-lactamase_A123G,beta-lactamase_123,TEM-1,beta-lactamase,P62593,0.839143,NO,123,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.834,-2.991,2.157,4.70061,0.039,H,A,0.52,-0.72,0.705,,41.26,PHH,-1.47367,0.221079,0.0010157,0.839143 Pab1_L153V,Pab1_153,Pab1,Pab1,P04147,0.839185,NO,153,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.039,-2.671,1.632,,0.46,E,A,,-0.95,,,,HHP,-1.17667,0.175299,0.000321212,0.839185 beta-lactamase_2500_T264W,beta-lactamase_2500_264,TEM-1,beta-lactamase_2500,P62593,0.839192,NO,264,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.361275,0.0119399,0.839192 beta-lactamase_2500_L219F,beta-lactamase_2500_219,TEM-1,beta-lactamase_2500,P62593,0.839354,NO,219,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.313,-2.825,1.512,,,I,A,0.55,-0.51,35.994,35.994,74.48,HHB,-1.21533,0.361275,0.00664345,0.839354 kka2_1:4_A222S,kka2_1:4_222,Kka2,kka2_1:4,P00552,0.839367,NO,222,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.725,-2.964,2.239,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.168804,0.00207657,0.839367 beta-lactamase_0_G43V,beta-lactamase_0_43,TEM-1,beta-lactamase_0,P62593,0.839381,NO,43,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.62,-3.754,3.134,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.0500837,0.00120151,0.839381 kka2_1:1_V75L,kka2_1:1_75,Kka2,kka2_1:1,P00552,0.839396,NO,75,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-2.06,-1.581,-0.479,,0.042,.,B,0.44,-0.2,2.815,,71.59,OHO,-1.563,0.520039,0.00693733,0.839396 beta-lactamase_0_G114Q,beta-lactamase_0_114,TEM-1,beta-lactamase_0,P62593,0.839417,NO,114,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.094,-4.039,2.945,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.0500837,0.00224919,0.839417 beta-lactamase_0_I45H,beta-lactamase_0_45,TEM-1,beta-lactamase_0,P62593,0.839427,NO,45,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-2.421,-3.408,0.987,,,E,B,0.48,-0.3,1.375,,77.62,HHA,-2.30267,0.0500837,0.00452842,0.839427 beta-lactamase_156_I280T,beta-lactamase_156_280,TEM-1,beta-lactamase_156,P62593,0.839441,NO,280,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.111618,0.0530888,0.839441 beta-lactamase_0_D83P,beta-lactamase_0_83,TEM-1,beta-lactamase_0,P62593,0.839526,NO,83,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.066,-3.748,2.682,,0.354,H,A,0.75,0.22,0.617,,48.95,HAH,-1.34733,0.0500837,0.00205968,0.839526 kka2_1:4_D250I,kka2_1:4_250,Kka2,kka2_1:4,P00552,0.839554,NO,250,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.015,-4.121,3.106,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.168804,0.0177103,0.839554 kka2_1:1_A108S,kka2_1:1_108,Kka2,kka2_1:1,P00552,0.839571,NO,108,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.061,-2.146,0.085,,0.243,.,B,0.46,-1.34,3.156,,71.59,HHO,-1.57033,0.520039,0.00751209,0.839571 beta-lactamase_0_A34R,beta-lactamase_0_34,TEM-1,beta-lactamase_0,P62593,0.83963,NO,34,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.059,-4.061,2.002,,,H,A,0.46,-0.54,3.998,,73.78,AHA,-1.74967,0.0500837,0.00407913,0.83963 beta-lactamase_0_G226H,beta-lactamase_0_226,TEM-1,beta-lactamase_0,P62593,0.839727,NO,226,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.461,-4.656,3.195,,0.701,T,l,0.29,-0.25,23.034,23.034,74.48,HOH,-1.42933,0.0500837,0.00665294,0.839727 beta-lactamase_0_M153E,beta-lactamase_0_153,TEM-1,beta-lactamase_0,P62593,0.839734,NO,153,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-3.193,-3.818,0.625,,0.14,T,A,0.55,-0.11,3.826,,77.62,PHO,-2.25767,0.0500837,0.00509109,0.839734 PSD95pdz3_V362Q,PSD95pdz3_362,PSD95pdz3,PSD95pdz3,P31016,0.839734,NO,362,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.465,-3.806,2.341,4.99436,,,,,19.6443,,,,PHP,-1.46467,0.0758425,0.000538527,0.839734 kka2_1:2_A34R,kka2_1:2_34,Kka2,kka2_1:2,P00552,0.839793,NO,34,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.928,-3.768,2.84,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.295029,0.00343484,0.839793 beta-lactamase_V72S,beta-lactamase_72,TEM-1,beta-lactamase,P62593,0.839801,NO,72,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.658,-3.477,1.819,5.80324,,H,A,2.78,-1.03,2.964,,65.73,BHH,-1.32167,0.221079,0.00501194,0.839801 beta-lactamase_0_H151F,beta-lactamase_0_151,TEM-1,beta-lactamase_0,P62593,0.839815,NO,151,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-2.96,-4.308,1.348,,0.594,H,A,0.17,0.1,9.375,,77.62,HBP,-2.34767,0.0500837,0.00216946,0.839815 beta-lactamase_2500_P217L,beta-lactamase_2500_217,TEM-1,beta-lactamase_2500,P62593,0.839854,NO,217,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-2.062,-3.634,1.572,,0.496,I,A,0.52,-0.33,0.431,,74.48,OOH,-1.64333,0.361275,0.00463211,0.839854 beta-lactamase_0_H151C,beta-lactamase_0_151,TEM-1,beta-lactamase_0,P62593,0.839856,NO,151,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-2.96,-5.124,2.164,,0.594,H,A,0.17,0.1,9.375,,77.62,HBP,-2.34767,0.0500837,0.00216946,0.839856 kka2_1:2_C192G,kka2_1:2_192,Kka2,kka2_1:2,P00552,0.839897,NO,192,C,G,CG,Special,Special,5.07,3.29388,-1.77612,159,121,75,-46,108.5,60.1,-48.4,-1.067,-3.557,2.49,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.295029,0.00485428,0.839897 kka2_1:8_D62M,kka2_1:8_62,Kka2,kka2_1:8,P00552,0.839943,NO,62,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.591,-4.884,3.293,,0.262,H,A,0.29,0.08,5.58,,64.39,PAA,-1.77833,0.100394,0.00744243,0.839943 kka2_1:8_D62M,kka2_1:8_62,Kka2,kka2_1:8,P00552,0.839943,NO,62,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.591,-4.884,3.293,,0.262,H,A,0.29,0.08,5.58,,64.39,PAA,-1.77833,0.100394,0.00744243,0.839943 Pab1_A158H,Pab1_158,Pab1,Pab1,P04147,0.839981,NO,158,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.154,-4.601,3.447,,,,,,,1.197,,56.33,HHP,-1.40733,0.175299,0.000649733,0.839981 beta-lactamase_0_G85A,beta-lactamase_0_85,TEM-1,beta-lactamase_0,P62593,0.84001,NO,85,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.011,-3.043,2.032,,0.805,T,l,0.29,1.7,2.25,,63.64,HOP,-1.68733,0.0500837,0.00252173,0.84001 gb1_T237Q,gb1_237,gb1,gb1,P06654,0.840014,NO,237,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.736,-3.725,1.989,,,,,,,0.218,,11.83,BPH,-2.27833,0.177985,0.00275316,0.840014 beta-lactamase_2500_R239E,beta-lactamase_2500_239,TEM-1,beta-lactamase_2500,P62593,0.840018,NO,239,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.361275,0.00213852,0.840018 beta-lactamase_0_V106E,beta-lactamase_0_106,TEM-1,beta-lactamase_0,P62593,0.840024,NO,106,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.218,-3.859,2.641,,0.258,T,A,0.44,0.24,0.952,,72.73,OHP,-1.04933,0.0500837,0.00304168,0.840024 beta-lactamase_L74A,beta-lactamase_74,TEM-1,beta-lactamase,P62593,0.840037,NO,74,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.296,-1.569,0.273,5.50288,,H,A,1.75,-0.91,1.581,,50,HHO,-1.34933,0.221079,0.00493255,0.840037 kka2_1:4_L67Y,kka2_1:4_67,Kka2,kka2_1:4,P00552,0.840039,NO,67,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.741,-3.966,3.225,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.168804,0.00102787,0.840039 kka2_1:2_I196L,kka2_1:2_196,Kka2,kka2_1:2,P00552,0.840095,NO,196,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-2.115,-1.762,-0.353,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.295029,0.0107273,0.840095 beta-lactamase_156_N130A,beta-lactamase_156_130,TEM-1,beta-lactamase_156,P62593,0.840125,NO,130,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-0.798,-3.303,2.505,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.111618,0.000683376,0.840125 beta-lactamase_0_M153P,beta-lactamase_0_153,TEM-1,beta-lactamase_0,P62593,0.84014,NO,153,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-3.193,-4.07,0.877,,0.14,T,A,0.55,-0.11,3.826,,77.62,PHO,-2.25767,0.0500837,0.00509109,0.84014 kka2_1:4_Y218D,kka2_1:4_218,Kka2,kka2_1:4,P00552,0.840171,NO,218,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-1.438,-3.939,2.501,,0.122,H,A,0.21,-0.69,1.022,,56.06,BHP,-1.17533,0.168804,0.0126098,0.840171 PSD95pdz3_L323A,PSD95pdz3_323,PSD95pdz3,PSD95pdz3,P31016,0.840177,NO,323,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.347,-2.759,1.412,5.12397,,,,,13.8825,,,,OHO,-1.121,0.0758425,0.00104644,0.840177 kka2_1:8_V80G,kka2_1:8_80,Kka2,kka2_1:8,P00552,0.840183,NO,80,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.144,-3.627,2.483,,0.358,E,B,1.48,-0.24,2.562,,63.64,HHH,-1.64633,0.100394,0.00488211,0.840183 kka2_1:8_V80G,kka2_1:8_80,Kka2,kka2_1:8,P00552,0.840183,NO,80,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.144,-3.627,2.483,,0.358,E,B,1.48,-0.24,2.562,,63.64,HHH,-1.64633,0.100394,0.00488211,0.840183 beta-lactamase_0_R59I,beta-lactamase_0_59,TEM-1,beta-lactamase_0,P62593,0.840218,NO,59,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.345,-4.065,2.72,,0.329,S,L,1.2,-0.09,2.919,,73.08,HBO,-2.24267,0.0500837,0.00318082,0.840218 beta-lactamase_625_G154T,beta-lactamase_625_154,TEM-1,beta-lactamase_625,P62593,0.84025,NO,154,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.823,-3.619,2.796,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.213352,0.00180205,0.84025 beta-lactamase_0_T187F,beta-lactamase_0_187,TEM-1,beta-lactamase_0,P62593,0.840325,NO,187,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.401,-4.141,2.74,,0.007,H,A,0.22,-1.19,3.259,,67.48,PPH,-1.69633,0.0500837,0.00491782,0.840325 kka2_1:8_C192Q,kka2_1:8_192,Kka2,kka2_1:8,P00552,0.840344,NO,192,C,Q,CQ,Special,Polar,5.07,6.24429,1.17429,154,121,146,25,108.5,143.8,35.3,-1.067,-4.263,3.196,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.100394,0.00485428,0.840344 kka2_1:8_C192Q,kka2_1:8_192,Kka2,kka2_1:8,P00552,0.840344,NO,192,C,Q,CQ,Special,Polar,5.07,6.24429,1.17429,154,121,146,25,108.5,143.8,35.3,-1.067,-4.263,3.196,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.100394,0.00485428,0.840344 kka2_1:4_V214F,kka2_1:4_214,Kka2,kka2_1:4,P00552,0.84036,NO,214,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.261,-3.945,2.684,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.168804,0.00692782,0.84036 gb1_N263I,gb1_263,gb1,gb1,P06654,0.840448,NO,263,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-1.162,-3.787,2.625,,,,,,,,,,APO,-2.04233,0.177985,0.0035297,0.840448 kka2_1:8_I196R,kka2_1:8_196,Kka2,kka2_1:8,P00552,0.840451,NO,196,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-2.115,-4.247,2.132,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.100394,0.0107273,0.840451 kka2_1:8_I196R,kka2_1:8_196,Kka2,kka2_1:8,P00552,0.840451,NO,196,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-2.115,-4.247,2.132,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.100394,0.0107273,0.840451 Pab1_A158I,Pab1_158,Pab1,Pab1,P04147,0.840466,NO,158,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.154,-3.126,1.972,,,,,,,1.197,,56.33,HHP,-1.40733,0.175299,0.000649733,0.840466 Pab1_V148R,Pab1_148,Pab1,Pab1,P04147,0.840478,NO,148,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.875,-3.794,1.919,,,,,,,,,,PHH,-1.43033,0.175299,0.00179641,0.840478 beta-lactamase_39_W208R,beta-lactamase_39_208,TEM-1,beta-lactamase_39,P62593,0.840511,NO,208,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-0.818,-4.158,3.34,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.0495842,0.00126609,0.840511 beta-lactamase_P249V,beta-lactamase_249,TEM-1,beta-lactamase,P62593,0.840527,NO,249,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.312,-2.803,1.491,5.10655,0.256,S,B,0.99,0.04,0.479,,72.73,OOA,-1.81367,0.221079,0.00220169,0.840527 PSD95pdz3_L379T,PSD95pdz3_379,PSD95pdz3,PSD95pdz3,P31016,0.840544,NO,379,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.347,-3.103,1.756,5.37777,,,,,16.8762,,,,HHB,-1.35667,0.0758425,0.00029733,0.840544 beta-lactamase_0_K254Y,beta-lactamase_0_254,TEM-1,beta-lactamase_0,P62593,0.84057,NO,254,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.0500837,0.00369,0.84057 beta-lactamase_F228H,beta-lactamase_228,TEM-1,beta-lactamase,P62593,0.840575,NO,228,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-2.342,-3.331,0.989,5.33448,0.154,E,B,1.1,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.221079,0.0046669,0.840575 beta-lactamase_0_G234E,beta-lactamase_0_234,TEM-1,beta-lactamase_0,P62593,0.840641,NO,234,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.62,-3.665,3.045,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.0500837,0.000889577,0.840641 beta-lactamase_E62R,beta-lactamase_62,TEM-1,beta-lactamase,P62593,0.840657,NO,62,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.193,-3.663,2.47,5.93066,0.342,S,B,1.52,-0.3,3.139,,73.08,AAB,-1.417,0.221079,0.00264802,0.840657 beta-lactamase_39_N274P,beta-lactamase_39_274,TEM-1,beta-lactamase_39,P62593,0.840658,NO,274,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.0495842,0.0110418,0.840658 beta-lactamase_L135T,beta-lactamase_135,TEM-1,beta-lactamase,P62593,0.840728,NO,135,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.002,-3.475,2.473,5.28497,0.117,H,A,1.07,-0.58,0.697,,43.71,PHH,-1.03767,0.221079,0.00244423,0.840728 kka2_1:4_L60D,kka2_1:4_60,Kka2,kka2_1:4,P00552,0.840729,NO,60,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.997,-4.183,3.186,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.168804,0.00262176,0.840729 kka2_1:4_L107P,kka2_1:4_107,Kka2,kka2_1:4,P00552,0.840738,NO,107,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.238,-4.14,2.902,,0.197,.,B,0.55,-1.1,0.398,,71.59,BHH,-2.143,0.168804,0.00561937,0.840738 beta-lactamase_2500_A40Q,beta-lactamase_2500_40,TEM-1,beta-lactamase_2500,P62593,0.840769,NO,40,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.402,-4.1,2.698,,0.155,S,B,0.46,0.21,0.953,,73.78,OHB,-1.40267,0.361275,0.00490026,0.840769 beta-lactamase_156_D174K,beta-lactamase_156_174,TEM-1,beta-lactamase_156,P62593,0.840794,NO,174,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.738,-3.457,2.719,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.111618,0.00125633,0.840794 beta-lactamase_2500_L197I,beta-lactamase_2500_197,TEM-1,beta-lactamase_2500,P62593,0.840871,NO,197,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.853,-2.968,2.115,,0.007,S,B,0.55,0.33,2.421,,60.14,HHP,-1.833,0.361275,0.00144602,0.840871 gb1_L233F,gb1_233,gb1,gb1,P06654,0.840881,NO,233,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-2.678,-3.783,1.105,,,,,,,0.822,,45.54,HHP,-2.30267,0.177985,0.00266958,0.840881 gb1_Y259H,gb1_259,gb1,gb1,P06654,0.840881,NO,259,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-1.78,-4.05,2.27,,,,,,,0.131,,11.83,PHH,-1.787,0.177985,0.00464313,0.840881 beta-lactamase_2500_I285A,beta-lactamase_2500_285,TEM-1,beta-lactamase_2500,P62593,0.840886,NO,285,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.361275,0.101555,0.840886 beta-lactamase_0_V31T,beta-lactamase_0_31,TEM-1,beta-lactamase_0,P62593,0.84089,NO,31,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.822,-2.805,0.983,,,H,A,0.44,-0.46,4.126,,73.78,BHB,-2.03767,0.0500837,0.00478065,0.84089 beta-lactamase_0_K144C,beta-lactamase_0_144,TEM-1,beta-lactamase_0,P62593,0.840896,NO,144,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-2.388,-5.107,2.719,,0.863,H,A,2.34,1.27,5.696,,77.62,OBA,-1.904,0.0500837,0.00481141,0.840896 beta-lactamase_L100C,beta-lactamase_100,TEM-1,beta-lactamase,P62593,0.840902,NO,100,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.218,-4.758,3.54,5.60291,0.343,,B,1.3,0.13,1.173,,63.29,AHH,-1.23467,0.221079,0.00413885,0.840902 beta-lactamase_R63N,beta-lactamase_63,TEM-1,beta-lactamase,P62593,0.840902,NO,63,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-0.943,-3.531,2.588,5.49979,0.218,,B,0.45,-0.31,0.677,,44.06,ABH,-0.992333,0.221079,0.00126938,0.840902 beta-lactamase_625_E119T,beta-lactamase_625_119,TEM-1,beta-lactamase_625,P62593,0.840914,NO,119,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.412,-3.526,2.114,,0.358,H,A,1.04,0.51,1.034,,63.99,BAH,-1.623,0.213352,0.00386966,0.840914 beta-lactamase_L55G,beta-lactamase_55,TEM-1,beta-lactamase,P62593,0.840931,NO,55,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.86,-3.665,1.805,,0.372,E,A,1.07,-0.36,1.423,,63.99,HHA,-2.247,0.221079,0.00403741,0.840931 beta-lactamase_0_R41G,beta-lactamase_0_41,TEM-1,beta-lactamase_0,P62593,0.840949,NO,41,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-0.942,-3.321,2.379,,0.321,E,B,1.2,-0.07,2.68,,65.03,HBH,-1.30267,0.0500837,0.00123327,0.840949 kka2_1:1_Q163M,kka2_1:1_163,Kka2,kka2_1:1,P00552,0.840979,NO,163,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.162,-2.88,0.718,,0.58,T,B,0.64,1.85,2.779,,64.02,BPO,-1.78333,0.520039,0.00719507,0.840979 beta-lactamase_0_E175F,beta-lactamase_0_175,TEM-1,beta-lactamase_0,P62593,0.841,NO,175,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.336,-4.36,2.024,,0.551,,A,1.04,1.05,2.334,,77.62,AAB,-1.31233,0.0500837,0.00482205,0.841 kka2_1:1_Q26K,kka2_1:1_26,Kka2,kka2_1:1,P00552,0.841183,NO,26,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.18,-2.687,0.507,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.520039,0.00708962,0.841183 beta-lactamase_0_D252Y,beta-lactamase_0_252,TEM-1,beta-lactamase_0,P62593,0.841188,NO,252,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.0500837,0.00575769,0.841188 kka2_1:4_E161T,kka2_1:4_161,Kka2,kka2_1:4,P00552,0.841227,NO,161,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.581,-2.315,0.734,,0.829,G,A,1.52,2.24,1.612,,92.05,AAB,-1.861,0.168804,0.00760103,0.841227 beta-lactamase_0_I229W,beta-lactamase_0_229,TEM-1,beta-lactamase_0,P62593,0.841232,NO,229,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.267,-5.365,4.098,,0.083,E,B,0.48,-0.76,1.69,,50,HHH,-1.58767,0.0500837,0.00477249,0.841232 PSD95pdz3_L360G,PSD95pdz3_360,PSD95pdz3,PSD95pdz3,P31016,0.841274,NO,360,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.431,-3.489,2.058,5.09284,,,,,14.2425,1.419,,86.88,HHP,-1.52667,0.0758425,0.000770471,0.841274 kka2_1:1_A65V,kka2_1:1_65,Kka2,kka2_1:1,P00552,0.841335,NO,65,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.744,-2.657,0.913,,0.437,H,A,0.46,-0.39,3.012,,63.64,HHB,-1.38733,0.520039,0.00709258,0.841335 beta-lactamase_0_T193I,beta-lactamase_0_193,TEM-1,beta-lactamase_0,P62593,0.841377,NO,193,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.914,-2.798,0.884,,0.439,H,a,0.22,0.33,11.546,11.546,63.99,HPO,-1.52133,0.0500837,0.00482669,0.841377 beta-lactamase_R176G,beta-lactamase_176,TEM-1,beta-lactamase,P62593,0.841384,NO,176,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-0.863,-3.358,2.495,5.61264,0.385,T,B,0.68,-0.63,,,,ABA,-1.38867,0.221079,0.00105554,0.841384 beta-lactamase_39_A77P,beta-lactamase_39_77,TEM-1,beta-lactamase_39,P62593,0.841399,NO,77,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.234,-3.879,2.645,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.0495842,0.00282362,0.841399 beta-lactamase_0_I244Q,beta-lactamase_0_244,TEM-1,beta-lactamase_0,P62593,0.841475,NO,244,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.555,-4.255,2.7,,,E,B,0.48,-0.84,1.241,,77.62,OHH,-1.385,0.0500837,0.00605379,0.841475 beta-lactamase_625_A215E,beta-lactamase_625_215,TEM-1,beta-lactamase_625,P62593,0.841493,NO,215,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.503,-3.531,2.028,,,,a,0.46,-0.93,3.583,,74.48,HHO,-1.42633,0.213352,0.00544007,0.841493 beta-lactamase_0_Y103F,beta-lactamase_0_103,TEM-1,beta-lactamase_0,P62593,0.841571,NO,103,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-1.33,-3.391,2.061,,0.613,S,l,0.21,1.21,1.646,,63.29,AHP,-1.48767,0.0500837,0.00443048,0.841571 kka2_1:8_L126F,kka2_1:8_126,Kka2,kka2_1:8,P00552,0.841597,NO,126,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.246,-3.893,2.647,,0.285,S,B,1.59,0.12,4.443,,51.89,PHA,-1.744,0.100394,0.0066485,0.841597 kka2_1:8_L126F,kka2_1:8_126,Kka2,kka2_1:8,P00552,0.841597,NO,126,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.246,-3.893,2.647,,0.285,S,B,1.59,0.12,4.443,,51.89,PHA,-1.744,0.100394,0.0066485,0.841597 beta-lactamase_0_E169N,beta-lactamase_0_169,TEM-1,beta-lactamase_0,P62593,0.841602,NO,169,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.23,-3.55,2.32,,0.337,,A,1.04,1,3.516,,73.08,PAH,-1.16533,0.0500837,0.00400994,0.841602 beta-lactamase_P165D,beta-lactamase_165,TEM-1,beta-lactamase,P62593,0.841701,NO,165,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.373,-3.54,2.167,5.33889,0.203,T,A,0.99,-0.31,0.414,,73.78,AOA,-1.359,0.221079,0.00549538,0.841701 beta-lactamase_39_P65W,beta-lactamase_39_65,TEM-1,beta-lactamase_39,P62593,0.841727,NO,65,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.894,-5.47,4.576,,0.098,E,B,0.52,-0.62,0.623,,40.56,HOH,-1.03233,0.0495842,0.00152776,0.841727 E1_Ubiquitin_Q40Q,E1_Ubiquitin_40,Uba1,E1_Ubiquitin,P0CG63,0.841733,NO,40,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-1.48,-1.48,,,0.387,G,A,,0.03,,,,OPP,-1.365,0.18783,0.0037961,0.841733 beta-lactamase_L38N,beta-lactamase_38,TEM-1,beta-lactamase,P62593,0.841747,NO,38,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.343,-4.007,2.664,5.23728,0.088,H,A,1.75,0.2,1.986,,64.34,PHO,-1.78033,0.221079,0.00373244,0.841747 beta-lactamase_0_S68H,beta-lactamase_0_68,TEM-1,beta-lactamase_0,P62593,0.841758,NO,68,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-0.913,-4.418,3.505,,0.064,G,A,0.27,-1.03,1.441,,64.69,HPP,-1.37233,0.0500837,0.000800065,0.841758 beta-lactamase_0_Y103V,beta-lactamase_0_103,TEM-1,beta-lactamase_0,P62593,0.841765,NO,103,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-1.33,-3.602,2.272,,0.613,S,l,0.21,1.21,1.646,,63.29,AHP,-1.48767,0.0500837,0.00443048,0.841765 kka2_1:1_A166K,kka2_1:1_166,Kka2,kka2_1:1,P00552,0.841791,NO,166,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.407,-3.569,1.162,,0.534,.,B,0.46,1.03,1.147,,71.59,HHO,-2.421,0.520039,0.00799912,0.841791 beta-lactamase_0_I45R,beta-lactamase_0_45,TEM-1,beta-lactamase_0,P62593,0.841931,NO,45,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-2.421,-4.043,1.622,,,E,B,0.48,-0.3,1.375,,77.62,HHA,-2.30267,0.0500837,0.00452842,0.841931 beta-lactamase_0_T139S,beta-lactamase_0_139,TEM-1,beta-lactamase_0,P62593,0.841937,NO,139,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.901,-2.265,0.364,,0.216,H,A,0.22,0.39,0.421,,77.62,PPH,-2.04667,0.0500837,0.00441837,0.841937 beta-lactamase_0_G114Y,beta-lactamase_0_114,TEM-1,beta-lactamase_0,P62593,0.841945,NO,114,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.094,-4.391,3.297,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.0500837,0.00224919,0.841945 beta-lactamase_625_D212V,beta-lactamase_625_212,TEM-1,beta-lactamase_625,P62593,0.841969,NO,212,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.624,-3.608,1.984,,0.037,,b,0.75,-0.58,1.516,,74.48,HAB,-1.77667,0.213352,0.00644302,0.841969 beta-lactamase_0_L136T,beta-lactamase_0_136,TEM-1,beta-lactamase_0,P62593,0.841992,NO,136,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.232,-3.487,2.255,,,H,A,0.55,-0.34,0.648,,48.95,HHH,-1.088,0.0500837,0.00442304,0.841992 kka2_1:1_D208A,kka2_1:1_208,Kka2,kka2_1:1,P00552,0.842074,NO,208,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.708,-3.331,2.623,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.520039,0.00212588,0.842074 kka2_1:1_Q163K,kka2_1:1_163,Kka2,kka2_1:1,P00552,0.842168,NO,163,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.162,-2.924,0.762,,0.58,T,B,0.64,1.85,2.779,,64.02,BPO,-1.78333,0.520039,0.00719507,0.842168 beta-lactamase_0_D231S,beta-lactamase_0_231,TEM-1,beta-lactamase_0,P62593,0.842172,NO,231,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.816,-3.186,2.37,,,E,B,0.75,-1.06,4.975,,65.38,HAB,-0.994,0.0500837,0.00107395,0.842172 kka2_1:8_H124Q,kka2_1:8_124,Kka2,kka2_1:8,P00552,0.842209,NO,124,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-0.84,-3.703,2.863,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.100394,0.00211296,0.842209 kka2_1:8_H124Q,kka2_1:8_124,Kka2,kka2_1:8,P00552,0.842209,NO,124,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-0.84,-3.703,2.863,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.100394,0.00211296,0.842209 kka2_1:2_F240C,kka2_1:2_240,Kka2,kka2_1:2,P00552,0.842244,NO,240,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-0.911,-4.889,3.978,,,H,A,0.58,-1.21,0.373,,50.38,BHH,-1.67267,0.295029,0.00552543,0.842244 beta-lactamase_0_W288C,beta-lactamase_0_288,TEM-1,beta-lactamase_0,P62593,0.842297,NO,288,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,,,,,,,,,,,,,BHO,,0.0500837,,0.842297 beta-lactamase_V42Y,beta-lactamase_42,TEM-1,beta-lactamase,P62593,0.84231,NO,42,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.564,-4.12,2.556,5.27904,0.017,E,B,1.64,-0.51,2.024,,63.99,BHO,-1.042,0.221079,0.00404515,0.84231 kka2_1:1_R44Q,kka2_1:1_44,Kka2,kka2_1:1,P00552,0.842316,NO,44,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.062,-2.483,0.421,,0.487,S,B,1.2,-0.35,2.717,,71.59,OBO,-1.80767,0.520039,0.00745043,0.842316 beta-lactamase_2500_R63H,beta-lactamase_2500_63,TEM-1,beta-lactamase_2500,P62593,0.842382,NO,63,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-0.943,-4.313,3.37,,0.218,,B,1.2,-0.31,0.929,,44.06,ABH,-0.992333,0.361275,0.00126938,0.842382 beta-lactamase_0_N134W,beta-lactamase_0_134,TEM-1,beta-lactamase_0,P62593,0.842487,NO,134,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-0.879,-5.545,4.666,,0.138,H,A,0.61,-0.6,3.776,,53.15,HPH,-1.02233,0.0500837,0.000644786,0.842487 kka2_1:2_Q61G,kka2_1:2_61,Kka2,kka2_1:2,P00552,0.842488,NO,61,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.982,-2.486,-0.496,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.295029,0.00612092,0.842488 kka2_1:2_A71C,kka2_1:2_71,Kka2,kka2_1:2,P00552,0.842531,NO,71,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.824,-5.109,3.285,,0.553,H,A,0.46,0.08,9.788,,64.39,HHP,-1.74033,0.295029,0.00727707,0.842531 kka2_1:2_L184R,kka2_1:2_184,Kka2,kka2_1:2,P00552,0.842549,NO,184,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.496,-2.591,1.095,,0.489,E,B,0.55,-0.06,14.044,14.044,63.26,AHH,-1.24833,0.295029,0.00518742,0.842549 kka2_1:1_Q155G,kka2_1:1_155,Kka2,kka2_1:1,P00552,0.842568,NO,155,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.606,-2.641,0.035,,0.525,T,A,0.4,1.49,4.415,,63.64,APA,-1.726,0.520039,0.00641853,0.842568 beta-lactamase_M115V,beta-lactamase_115,TEM-1,beta-lactamase,P62593,0.84257,NO,115,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.389,-3.055,1.666,4.89743,0.019,E,B,1.3,0.08,1.236,,69.58,OHP,-1.25433,0.221079,0.0034337,0.84257 beta-lactamase_R162A,beta-lactamase_162,TEM-1,beta-lactamase,P62593,0.842575,NO,162,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.016,-3.127,2.111,5.34456,0.124,S,B,0.68,-0.37,31.656,31.656,64.69,ABH,-1.25,0.221079,0.000561334,0.842575 beta-lactamase_G142T,beta-lactamase_142,TEM-1,beta-lactamase,P62593,0.842606,NO,142,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.707,-3.568,2.861,4.55474,0.034,,p,0.77,-0.64,1.947,,64.69,OOO,-0.834,0.221079,0.00060149,0.842606 beta-lactamase_156_S104D,beta-lactamase_156_104,TEM-1,beta-lactamase_156,P62593,0.842739,NO,104,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.015,-3.41,2.395,,0.04,,b,0.27,0.57,4.02,,63.29,HPO,-1.05267,0.111618,0.00218083,0.842739 beta-lactamase_0_I54P,beta-lactamase_0_54,TEM-1,beta-lactamase_0,P62593,0.842763,NO,54,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-2.838,-4.045,1.207,,0.669,E,B,0.48,-0.14,0.541,,73.78,BHH,-2.337,0.0500837,0.00403589,0.842763 beta-lactamase_625_L146C,beta-lactamase_625_146,TEM-1,beta-lactamase_625,P62593,0.84279,NO,146,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.462,-4.847,3.385,,0.007,H,A,0.55,-0.56,2.16,,64.69,AHP,-1.656,0.213352,0.00474542,0.84279 beta-lactamase_39_N130M,beta-lactamase_39_130,TEM-1,beta-lactamase_39,P62593,0.84283,NO,130,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-0.798,-4.705,3.907,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.0495842,0.000683376,0.84283 Pab1_L191P,Pab1_191,Pab1,Pab1,P04147,0.842838,NO,191,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.2,-3.918,2.718,,0.204,E,B,,2.24,,,,HHP,-1.20133,0.175299,0.000583797,0.842838 beta-lactamase_0_S51C,beta-lactamase_0_51,TEM-1,beta-lactamase_0,P62593,0.842843,NO,51,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.526,-4.878,3.352,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.0500837,0.00504821,0.842843 kka2_1:8_H139G,kka2_1:8_139,Kka2,kka2_1:8,P00552,0.842843,NO,139,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-2.809,-2.92,0.111,,0.471,H,A,0.17,0.68,28.583,28.583,63.64,BBB,-2.22,0.100394,0.00734779,0.842843 kka2_1:8_H139G,kka2_1:8_139,Kka2,kka2_1:8,P00552,0.842843,NO,139,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-2.809,-2.92,0.111,,0.471,H,A,0.17,0.68,28.583,28.583,63.64,BBB,-2.22,0.100394,0.00734779,0.842843 kka2_1:8_D33A,kka2_1:8_33,Kka2,kka2_1:8,P00552,0.842852,NO,33,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.186,-2.11,-0.076,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.100394,0.00633568,0.842852 kka2_1:8_D33A,kka2_1:8_33,Kka2,kka2_1:8,P00552,0.842852,NO,33,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.186,-2.11,-0.076,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.100394,0.00633568,0.842852 beta-lactamase_0_R202M,beta-lactamase_0_202,TEM-1,beta-lactamase_0,P62593,0.842866,NO,202,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.292,-4.499,3.207,,0.188,H,A,1.2,0.62,7.016,,77.62,PBP,-1.54767,0.0500837,0.00321899,0.842866 kka2_1:4_W69Y,kka2_1:4_69,Kka2,kka2_1:4,P00552,0.842933,NO,69,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-0.859,-2.519,1.66,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.168804,0.0012874,0.842933 kka2_1:1_E3L,kka2_1:1_3,Kka2,kka2_1:1,P00552,0.842957,NO,3,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.199,-3.455,1.256,,,,,,,3.435,,92.05,HAP,-2.11567,0.520039,0.00267607,0.842957 beta-lactamase_0_A183R,beta-lactamase_0_183,TEM-1,beta-lactamase_0,P62593,0.842984,NO,183,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.231,-3.825,2.594,,0.155,H,A,0.46,-0.91,1.48,,77.62,HHH,-1.53367,0.0500837,0.00296631,0.842984 beta-lactamase_2500_H94P,beta-lactamase_2500_94,TEM-1,beta-lactamase_2500,P62593,0.843024,NO,94,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-2.5,-2.499,-0.001,,0.776,,B,0.17,1.24,1.176,,77.62,HBH,-1.872,0.361275,0.00389226,0.843024 gb1_L238F,gb1_238,gb1,gb1,P06654,0.84303,NO,238,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-2.98,-1.886,-1.094,,,,,,,0.504,,45.54,PHB,-2.58633,0.177985,0.00205885,0.84303 beta-lactamase_0_G85Y,beta-lactamase_0_85,TEM-1,beta-lactamase_0,P62593,0.843059,NO,85,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.011,-4.409,3.398,,0.805,T,l,0.29,1.7,2.25,,63.64,HOP,-1.68733,0.0500837,0.00252173,0.843059 kka2_1:8_G164V,kka2_1:8_164,Kka2,kka2_1:8,P00552,0.843084,NO,164,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.869,-3.836,2.967,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.100394,0.00442091,0.843084 kka2_1:8_G164V,kka2_1:8_164,Kka2,kka2_1:8,P00552,0.843084,NO,164,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.869,-3.836,2.967,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.100394,0.00442091,0.843084 PSD95pdz3_L323S,PSD95pdz3_323,PSD95pdz3,PSD95pdz3,P31016,0.843087,NO,323,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.347,-3.292,1.945,5.12397,,,,,13.8825,,,,OHO,-1.121,0.0758425,0.00104644,0.843087 kka2_1:4_E111Y,kka2_1:4_111,Kka2,kka2_1:4,P00552,0.843133,NO,111,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.28,-4.387,2.107,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.168804,0.00746789,0.843133 beta-lactamase_0_V101P,beta-lactamase_0_101,TEM-1,beta-lactamase_0,P62593,0.843205,NO,101,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.295,-4.04,2.745,,0.342,,B,0.44,0,1.61,,73.08,HHA,-1.54367,0.0500837,0.00374492,0.843205 beta-lactamase_0_V157H,beta-lactamase_0_157,TEM-1,beta-lactamase_0,P62593,0.843258,NO,157,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.751,-3.319,1.568,,0.308,S,a,0.44,-0.75,3.106,,69.58,BHP,-2.00767,0.0500837,0.00506849,0.843258 beta-lactamase_V258T,beta-lactamase_258,TEM-1,beta-lactamase,P62593,0.843273,NO,258,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.975,-2.157,0.182,5.16083,,E,B,1.64,-1.02,2.124,,67.83,HHH,-1.67667,0.221079,0.007931,0.843273 kka2_1:4_A129E,kka2_1:4_129,Kka2,kka2_1:4,P00552,0.843304,NO,129,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.656,-2.346,0.69,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.168804,0.00726862,0.843304 beta-lactamase_156_T179V,beta-lactamase_156_179,TEM-1,beta-lactamase_156,P62593,0.843314,NO,179,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.085,-3.247,2.162,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.111618,0.00226045,0.843314 beta-lactamase_I140A,beta-lactamase_140,TEM-1,beta-lactamase,P62593,0.84333,NO,140,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.733,-3.145,1.412,5.29918,0.128,H,A,1,0.41,1.16,,73.08,PHO,-1.48733,0.221079,0.00597777,0.84333 beta-lactamase_156_M115G,beta-lactamase_156_115,TEM-1,beta-lactamase_156,P62593,0.843356,NO,115,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.389,-3.632,2.243,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.111618,0.0034337,0.843356 kka2_1:2_E142N,kka2_1:2_142,Kka2,kka2_1:2,P00552,0.843356,NO,142,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.221,-3.851,1.63,,0.471,H,A,1.52,0.85,3.693,,65.53,HAB,-2.08033,0.295029,0.00748883,0.843356 beta-lactamase_0_N134P,beta-lactamase_0_134,TEM-1,beta-lactamase_0,P62593,0.843366,NO,134,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-0.879,-3.877,2.998,,0.138,H,A,0.61,-0.6,3.776,,53.15,HPH,-1.02233,0.0500837,0.000644786,0.843366 Pab1_Y197G,Pab1_197,Pab1,Pab1,P04147,0.843405,NO,197,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-1.345,-3.496,2.151,,,,,,,0.891,,80.42,HHH,-1.41767,0.175299,0.00302474,0.843405 beta-lactamase_0_T263F,beta-lactamase_0_263,TEM-1,beta-lactamase_0,P62593,0.843433,NO,263,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.0500837,0.0110582,0.843433 gb1_T251D,gb1_251,gb1,gb1,P06654,0.843456,NO,251,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.794,-3.095,1.301,,,,,,,3.514,3.514,37.28,HPH,-1.56067,0.177985,0.00232932,0.843456 beta-lactamase_0_N130F,beta-lactamase_0_130,TEM-1,beta-lactamase_0,P62593,0.843471,NO,130,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-0.798,-4.292,3.494,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.0500837,0.000683376,0.843471 kka2_1:4_P194R,kka2_1:4_194,Kka2,kka2_1:4,P00552,0.843476,NO,194,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.846,-3.983,3.137,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.168804,0.00314194,0.843476 beta-lactamase_P165R,beta-lactamase_165,TEM-1,beta-lactamase,P62593,0.843508,NO,165,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.373,-3.877,2.504,5.33889,0.203,T,A,0.99,-0.31,0.414,,73.78,AOA,-1.359,0.221079,0.00549538,0.843508 kka2_1:8_V185A,kka2_1:8_185,Kka2,kka2_1:8,P00552,0.843508,NO,185,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.045,-2.271,1.226,,0.058,E,B,1.48,-0.49,1.234,,46.97,HHH,-1.184,0.100394,0.00367031,0.843508 kka2_1:8_V185A,kka2_1:8_185,Kka2,kka2_1:8,P00552,0.843508,NO,185,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.045,-2.271,1.226,,0.058,E,B,1.48,-0.49,1.234,,46.97,HHH,-1.184,0.100394,0.00367031,0.843508 beta-lactamase_D174S,beta-lactamase_174,TEM-1,beta-lactamase,P62593,0.843512,NO,174,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.738,-3.161,2.423,5.44133,0.238,,B,1.22,-0.1,,,,PAA,-1.91233,0.221079,0.00125633,0.843512 hsp90_A587G,hsp90_587,hsp90,hsp90,P02829,0.843574,NO,587,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.456,-2.511,0,4.91216,0.049,H,A,0.55,-0.02,,,,PHP,-2.757,0.368192,0.000222939,0.843574 kka2_1:1_D52V,kka2_1:1_52,Kka2,kka2_1:1,P00552,0.843583,NO,52,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.271,-3.601,1.33,,0.22,E,B,0.75,0.8,2.64,,71.59,PAH,-2.38367,0.520039,0.00175694,0.843583 beta-lactamase_0_V31F,beta-lactamase_0_31,TEM-1,beta-lactamase_0,P62593,0.843607,NO,31,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.822,-2.736,0.914,,,H,A,0.44,-0.46,4.126,,73.78,BHB,-2.03767,0.0500837,0.00478065,0.843607 beta-lactamase_39_D212F,beta-lactamase_39_212,TEM-1,beta-lactamase_39,P62593,0.84361,NO,212,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.624,-4.334,2.71,,0.037,,b,0.75,-0.58,10.748,10.748,74.48,HAB,-1.77667,0.0495842,0.00644302,0.84361 beta-lactamase_G263M,beta-lactamase_263,TEM-1,beta-lactamase,P62593,0.84364,NO,263,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-2.031,-4.812,2.781,5.09799,0.517,S,l,0.77,0.31,16.425,16.425,77.62,POP,-1.78267,0.221079,0.0110582,0.84364 beta-lactamase_R202M,beta-lactamase_202,TEM-1,beta-lactamase,P62593,0.84364,NO,202,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.292,-4.499,3.207,5.16273,0.188,H,A,0.68,0.62,1.918,,77.62,PBP,-1.54767,0.221079,0.00321899,0.84364 beta-lactamase_0_E169C,beta-lactamase_0_169,TEM-1,beta-lactamase_0,P62593,0.843748,NO,169,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.23,-5.088,3.858,,0.337,,A,1.04,1,3.516,,73.08,PAH,-1.16533,0.0500837,0.00400994,0.843748 beta-lactamase_I283Q,beta-lactamase_283,TEM-1,beta-lactamase,P62593,0.843754,NO,283,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.638,-4.217,2.579,5.4178,0.165,H,A,1.23,0.04,1.576,,69.23,HHB,-1.735,0.221079,0.0429138,0.843754 PSD95pdz3_R318F,PSD95pdz3_318,PSD95pdz3,PSD95pdz3,P31016,0.843816,NO,318,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.582,-3.974,2.392,4.94876,,,,,17.5609,,,,BBO,-1.40567,0.0758425,0.00110471,0.843816 kka2_1:8_F263Y,kka2_1:8_263,Kka2,kka2_1:8,P00552,0.843825,NO,263,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-0.911,-3.189,2.278,,0.006,G,A,1.62,-0.12,0.928,,45.83,AHH,-0.92,0.100394,0.0172454,0.843825 kka2_1:8_F263Y,kka2_1:8_263,Kka2,kka2_1:8,P00552,0.843825,NO,263,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-0.911,-3.189,2.278,,0.006,G,A,1.62,-0.12,0.928,,45.83,AHH,-0.92,0.100394,0.0172454,0.843825 beta-lactamase_0_A185K,beta-lactamase_0_185,TEM-1,beta-lactamase_0,P62593,0.843845,NO,185,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.406,-3.666,2.26,,,H,A,0.46,-1.02,1.203,,65.03,HHP,-1.84033,0.0500837,0.00467449,0.843845 hsp90_A587P,hsp90_587,hsp90,hsp90,P02829,0.843865,NO,587,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.456,-3.033,0,4.91216,0.049,H,A,0.55,-0.02,,,,PHP,-2.757,0.368192,0.000222939,0.843865 beta-lactamase_P143A,beta-lactamase_143,TEM-1,beta-lactamase,P62593,0.843873,NO,143,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.967,-3.126,2.159,5.16366,0.075,H,A,0.99,-0.37,0.479,,66.78,OOB,-1.354,0.221079,0.00114551,0.843873 gb1_N263G,gb1_263,gb1,gb1,P06654,0.843881,NO,263,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-1.162,-2.685,1.523,,,,,,,,,,APO,-2.04233,0.177985,0.0035297,0.843881 gb1_T237H,gb1_237,gb1,gb1,P06654,0.843881,NO,237,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.736,-4.277,2.541,,,,,,,0.218,,11.83,BPH,-2.27833,0.177985,0.00275316,0.843881 beta-lactamase_0_Y262E,beta-lactamase_0_262,TEM-1,beta-lactamase_0,P62593,0.843962,NO,262,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.0500837,0.00853516,0.843962 beta-lactamase_2500_P165I,beta-lactamase_2500_165,TEM-1,beta-lactamase_2500,P62593,0.843983,NO,165,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.373,-3.815,2.442,,0.203,T,A,0.52,-0.31,0.414,,73.78,AOA,-1.359,0.361275,0.00549538,0.843983 kka2_1:1_Q155L,kka2_1:1_155,Kka2,kka2_1:1,P00552,0.843993,NO,155,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.606,-3.573,0.967,,0.525,T,A,0.4,1.49,4.415,,63.64,APA,-1.726,0.520039,0.00641853,0.843993 beta-lactamase_D212S,beta-lactamase_212,TEM-1,beta-lactamase,P62593,0.843998,NO,212,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.624,-2.471,0.847,4.9705,0.037,,b,1.3,-0.58,12.482,,74.48,HAB,-1.77667,0.221079,0.00644302,0.843998 beta-lactamase_0_G194Q,beta-lactamase_0_194,TEM-1,beta-lactamase_0,P62593,0.844052,NO,194,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.396,-3.925,2.529,,0.276,S,b,0.29,0.36,3.017,,67.83,POA,-1.832,0.0500837,0.00392163,0.844052 Pab1_S165W,Pab1_165,Pab1,Pab1,P04147,0.844112,NO,165,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.146,-5.14,3.994,,0.12,,a,,0.11,,,,BPB,-1.56867,0.175299,0.000307838,0.844112 kka2_1:8_D156I,kka2_1:8_156,Kka2,kka2_1:8,P00552,0.844142,NO,156,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.696,-4.017,2.321,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.100394,0.00926998,0.844142 kka2_1:8_D156I,kka2_1:8_156,Kka2,kka2_1:8,P00552,0.844142,NO,156,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.696,-4.017,2.321,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.100394,0.00926998,0.844142 Pab1_Y197N,Pab1_197,Pab1,Pab1,P04147,0.844165,NO,197,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-1.345,-3.893,2.548,,,,,,,0.891,,80.42,HHH,-1.41767,0.175299,0.00302474,0.844165 kka2_1:1_E160D,kka2_1:1_160,Kka2,kka2_1:1,P00552,0.844186,NO,160,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.683,-1.462,-0.221,,0.989,G,A,1.04,2.28,0.273,,71.59,AAA,-1.36133,0.520039,0.00935762,0.844186 beta-lactamase_W208F,beta-lactamase_208,TEM-1,beta-lactamase,P62593,0.844199,NO,208,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-0.818,-3.392,2.574,5.26277,0.067,H,A,0.99,-0.65,,,,AHH,-1.44133,0.221079,0.00126609,0.844199 Pab1_D138V,Pab1_138,Pab1,Pab1,P04147,0.844248,NO,138,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.128,-3.564,2.436,,0.427,,B,,-0.03,,,,HAP,-1.13967,0.175299,0.000567877,0.844248 beta-lactamase_625_R273E,beta-lactamase_625_273,TEM-1,beta-lactamase_625,P62593,0.844302,NO,273,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.314,-2.209,-0.105,,0.564,H,A,1.2,1.57,1.455,,73.78,ABP,-1.841,0.213352,0.0077952,0.844302 beta-lactamase_2500_G216M,beta-lactamase_2500_216,TEM-1,beta-lactamase_2500,P62593,0.844406,NO,216,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.477,-4.925,3.448,,0.437,I,A,0.29,-0.58,1.983,,74.48,HOO,-1.68067,0.361275,0.00639568,0.844406 beta-lactamase_L247W,beta-lactamase_247,TEM-1,beta-lactamase,P62593,0.844416,NO,247,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.48,-5.32,3.84,5.28771,0.007,E,B,2.89,-0.72,2.951,,63.99,HHO,-1.79833,0.221079,0.00611275,0.844416 kka2_1:2_E235V,kka2_1:2_235,Kka2,kka2_1:2,P00552,0.844456,NO,235,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.955,-2.86,0.905,,0.631,H,A,1.04,0.12,26.048,26.048,65.53,OAH,-2.07267,0.295029,0.0102806,0.844456 kka2_1:1_H139Q,kka2_1:1_139,Kka2,kka2_1:1,P00552,0.844499,NO,139,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-2.809,-2.861,0.052,,0.471,H,A,0.17,0.68,1.153,,63.64,BBB,-2.22,0.520039,0.00734779,0.844499 beta-lactamase_0_R273Y,beta-lactamase_0_273,TEM-1,beta-lactamase_0,P62593,0.844505,NO,273,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.314,-4.336,2.022,,0.564,H,A,1.2,1.57,20.248,20.248,73.78,ABP,-1.841,0.0500837,0.0077952,0.844505 kka2_1:8_G201E,kka2_1:8_201,Kka2,kka2_1:8,P00552,0.844522,NO,201,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.56,-2.596,1.036,,0.149,T,l,0.75,-0.57,2.152,,52.65,POB,-1.92233,0.100394,0.00820117,0.844522 kka2_1:8_G201E,kka2_1:8_201,Kka2,kka2_1:8,P00552,0.844522,NO,201,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.56,-2.596,1.036,,0.149,T,l,0.75,-0.57,2.152,,52.65,POB,-1.92233,0.100394,0.00820117,0.844522 kka2_1:4_R122C,kka2_1:4_122,Kka2,kka2_1:4,P00552,0.844621,NO,122,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.175,-5.179,3.004,,0.487,H,A,0.16,0.26,16.436,16.436,71.59,BBH,-1.53833,0.168804,0.00736512,0.844621 kka2_1:1_P76Q,kka2_1:1_76,Kka2,kka2_1:1,P00552,0.844883,NO,76,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.449,-3.171,1.722,,0.331,.,B,0.52,-0.41,0.345,,63.64,HOO,-1.662,0.520039,0.00625685,0.844883 beta-lactamase_E46C,beta-lactamase_46,TEM-1,beta-lactamase,P62593,0.844909,NO,46,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.94,-3.249,1.309,5.36461,0.021,E,B,1.51,0.14,0.373,,59.44,HAH,-2.079,0.221079,0.00427568,0.844909 PSD95pdz3_I327F,PSD95pdz3_327,PSD95pdz3,PSD95pdz3,P31016,0.844913,NO,327,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.63,-3.299,1.669,5.7413,,,,,14.0388,,,,PHH,-1.50167,0.0758425,0.000998774,0.844913 kka2_1:8_L241N,kka2_1:8_241,Kka2,kka2_1:8,P00552,0.844934,NO,241,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.158,-4.222,3.064,,0.08,H,A,1.59,-0.82,1.136,,63.26,HHH,-1.58533,0.100394,0.0117299,0.844934 kka2_1:8_L241N,kka2_1:8_241,Kka2,kka2_1:8,P00552,0.844934,NO,241,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.158,-4.222,3.064,,0.08,H,A,1.59,-0.82,1.136,,63.26,HHH,-1.58533,0.100394,0.0117299,0.844934 kka2_1:4_M116C,kka2_1:4_116,Kka2,kka2_1:4,P00552,0.844957,NO,116,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-2.482,-3.43,0.948,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.168804,0.00745147,0.844957 beta-lactamase_L223S,beta-lactamase_223,TEM-1,beta-lactamase,P62593,0.844982,NO,223,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.055,-3.587,2.532,5.42318,0.27,,B,1.3,0.09,1.511,,74.48,HHO,-1.35033,0.221079,0.00372793,0.844982 beta-lactamase_M268R,beta-lactamase_268,TEM-1,beta-lactamase,P62593,0.845023,NO,268,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-2.023,-2.544,0.521,5.4797,0.471,H,A,0.09,0.3,1.071,,65.73,PHA,-2.16233,0.221079,0.0102525,0.845023 beta-lactamase_625_L135K,beta-lactamase_625_135,TEM-1,beta-lactamase_625,P62593,0.845033,NO,135,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.002,-3.751,2.749,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.213352,0.00244423,0.845033 PSD95pdz3_V386L,PSD95pdz3_386,PSD95pdz3,PSD95pdz3,P31016,0.845037,NO,386,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.465,-2.365,0.9,5.18836,,,,,17.5429,,,,PHP,-1.463,0.0758425,0.000184509,0.845037 beta-lactamase_0_R220S,beta-lactamase_0_220,TEM-1,beta-lactamase_0,P62593,0.845068,NO,220,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-0.942,-3.349,2.407,,0.295,I,A,1.2,-0.76,21.573,21.573,74.48,HBP,-1.33633,0.0500837,0.00232421,0.845068 PSD95pdz3_I341T,PSD95pdz3_341,PSD95pdz3,PSD95pdz3,P31016,0.845069,NO,341,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.63,-3.103,1.473,5.73946,,,,,10.3187,,,,HHH,-1.50033,0.0758425,0.000824087,0.845069 beta-lactamase_0_T263K,beta-lactamase_0_263,TEM-1,beta-lactamase_0,P62593,0.845086,NO,263,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.0500837,0.0110582,0.845086 beta-lactamase_0_A200W,beta-lactamase_0_200,TEM-1,beta-lactamase_0,P62593,0.845103,NO,200,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.878,-5.525,3.647,,0.757,H,A,0.46,-0.19,16.368,16.368,77.62,HHP,-2.001,0.0500837,0.0060056,0.845103 beta-lactamase_0_H151D,beta-lactamase_0_151,TEM-1,beta-lactamase_0,P62593,0.845126,NO,151,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-2.96,-3.624,0.664,,0.594,H,A,0.17,0.1,9.375,,77.62,HBP,-2.34767,0.0500837,0.00216946,0.845126 beta-lactamase_G154R,beta-lactamase_154,TEM-1,beta-lactamase,P62593,0.845141,NO,154,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.823,-3.969,3.146,5.40944,0.54,T,l,0.77,-0.56,2.283,,64.69,HOA,-1.635,0.221079,0.00180205,0.845141 gb1_K276P,gb1_276,gb1,gb1,P06654,0.84515,NO,276,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.456,-3.585,2.129,,,,,,,0.236,,12.72,PBP,-1.65133,0.177985,0.00620493,0.84515 beta-lactamase_0_V259G,beta-lactamase_0_259,TEM-1,beta-lactamase_0,P62593,0.84523,NO,259,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.0500837,0.0070773,0.84523 beta-lactamase_0_M184I,beta-lactamase_0_184,TEM-1,beta-lactamase_0,P62593,0.845252,NO,184,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.593,-2.332,0.739,,,H,A,0.55,-0.87,13.292,13.292,62.94,HHH,-1.41,0.0500837,0.00356019,0.845252 beta-lactamase_G226P,beta-lactamase_226,TEM-1,beta-lactamase,P62593,0.845268,NO,226,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.461,-3.96,2.499,5.70682,0.701,T,l,0.77,-0.25,3.199,,74.48,HOH,-1.42933,0.221079,0.00665294,0.845268 beta-lactamase_L73G,beta-lactamase_73,TEM-1,beta-lactamase,P62593,0.845283,NO,73,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.507,-3.739,2.232,5.84139,,H,A,1.75,-0.64,2.09,,67.83,HHH,-1.487,0.221079,0.00488983,0.845283 beta-lactamase_2500_I280M,beta-lactamase_2500_280,TEM-1,beta-lactamase_2500,P62593,0.845285,NO,280,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.361275,0.0530888,0.845285 beta-lactamase_0_D252I,beta-lactamase_0_252,TEM-1,beta-lactamase_0,P62593,0.845299,NO,252,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.0500837,0.00575769,0.845299 kka2_1:8_V36L,kka2_1:8_36,Kka2,kka2_1:8,P00552,0.845302,NO,36,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-0.898,-2.711,1.813,,0.292,E,B,1.48,0.21,0.938,,52.27,HHH,-1.484,0.100394,0.00245633,0.845302 kka2_1:8_V36L,kka2_1:8_36,Kka2,kka2_1:8,P00552,0.845302,NO,36,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-0.898,-2.711,1.813,,0.292,E,B,1.48,0.21,0.938,,52.27,HHH,-1.484,0.100394,0.00245633,0.845302 kka2_1:8_E111G,kka2_1:8_111,Kka2,kka2_1:8,P00552,0.845381,NO,111,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.28,-2.822,0.542,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.100394,0.00746789,0.845381 kka2_1:8_E111G,kka2_1:8_111,Kka2,kka2_1:8,P00552,0.845381,NO,111,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.28,-2.822,0.542,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.100394,0.00746789,0.845381 beta-lactamase_0_L55A,beta-lactamase_0_55,TEM-1,beta-lactamase_0,P62593,0.845455,NO,55,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.86,-2.512,0.652,,0.372,E,A,0.55,-0.36,1.967,,63.99,HHA,-2.247,0.0500837,0.00403741,0.845455 beta-lactamase_0_D252H,beta-lactamase_0_252,TEM-1,beta-lactamase_0,P62593,0.845516,NO,252,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.0500837,0.00575769,0.845516 kka2_1:4_P132Q,kka2_1:4_132,Kka2,kka2_1:4,P00552,0.84552,NO,132,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.775,-3.926,3.151,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.168804,0.0018489,0.84552 kka2_1:4_A79F,kka2_1:4_79,Kka2,kka2_1:4,P00552,0.845531,NO,79,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.368,-4.451,2.083,,0.563,.,B,0.46,-0.43,2.291,,71.59,HHH,-1.752,0.168804,0.00664821,0.845531 beta-lactamase_0_R202I,beta-lactamase_0_202,TEM-1,beta-lactamase_0,P62593,0.845592,NO,202,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.292,-4.027,2.735,,0.188,H,A,1.2,0.62,7.016,,77.62,PBP,-1.54767,0.0500837,0.00321899,0.845592 beta-lactamase_0_R81K,beta-lactamase_0_81,TEM-1,beta-lactamase_0,P62593,0.845596,NO,81,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.466,-2.393,0.927,,0.218,H,A,1.2,1.66,0.332,,50,PBH,-1.60667,0.0500837,0.00499763,0.845596 beta-lactamase_0_P143R,beta-lactamase_0_143,TEM-1,beta-lactamase_0,P62593,0.845635,NO,143,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.967,-3.999,3.032,,0.075,H,A,0.52,-0.37,11.868,11.868,66.78,OOB,-1.354,0.0500837,0.00114551,0.845635 kka2_1:4_M1R,kka2_1:4_1,Kka2,kka2_1:4,P00552,0.845649,NO,1,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.787,-3.648,1.861,,,,,,,1.347,,62.12,NAHH,-1.787,0.168804,0.00251939,0.845649 beta-lactamase_2500_A34C,beta-lactamase_2500_34,TEM-1,beta-lactamase_2500,P62593,0.84569,NO,34,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.059,-4.764,2.705,,,H,A,0.46,-0.54,2.921,,73.78,AHA,-1.74967,0.361275,0.00407913,0.84569 beta-lactamase_0_S96P,beta-lactamase_0_96,TEM-1,beta-lactamase_0,P62593,0.845697,NO,96,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.27,-2.878,0.608,,0.368,,b,0.27,0.39,2.516,,73.78,HPP,-2.019,0.0500837,0.00551835,0.845697 kka2_1:8_L184H,kka2_1:8_184,Kka2,kka2_1:8,P00552,0.845723,NO,184,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.496,-4.936,3.44,,0.489,E,B,0.55,-0.06,4.495,,63.26,AHH,-1.24833,0.100394,0.00518742,0.845723 kka2_1:8_L184H,kka2_1:8_184,Kka2,kka2_1:8,P00552,0.845723,NO,184,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.496,-4.936,3.44,,0.489,E,B,0.55,-0.06,4.495,,63.26,AHH,-1.24833,0.100394,0.00518742,0.845723 kka2_1:4_Q219H,kka2_1:4_219,Kka2,kka2_1:4,P00552,0.845726,NO,219,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-0.93,-4.282,3.352,,0.088,H,A,0.64,-0.85,1.537,,50,HPA,-1.05167,0.168804,0.00237913,0.845726 kka2_1:1_L67R,kka2_1:1_67,Kka2,kka2_1:1,P00552,0.84579,NO,67,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.741,-3.961,3.22,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.520039,0.00102787,0.84579 kka2_1:1_F240V,kka2_1:1_240,Kka2,kka2_1:1,P00552,0.845856,NO,240,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-0.911,-3.287,2.376,,,H,A,1.62,-1.21,5.798,,50.38,BHH,-1.67267,0.520039,0.00552543,0.845856 kka2_1:2_A129W,kka2_1:2_129,Kka2,kka2_1:2,P00552,0.845918,NO,129,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.656,-5.587,3.931,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.295029,0.00726862,0.845918 beta-lactamase_0_E119T,beta-lactamase_0_119,TEM-1,beta-lactamase_0,P62593,0.845924,NO,119,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.412,-3.526,2.114,,0.358,H,A,1.04,0.51,3.396,,63.99,BAH,-1.623,0.0500837,0.00386966,0.845924 Pab1_Y197S,Pab1_197,Pab1,Pab1,P04147,0.845977,NO,197,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-1.345,-3.524,2.179,,,,,,,0.891,,80.42,HHH,-1.41767,0.175299,0.00302474,0.845977 kka2_1:4_P12W,kka2_1:4_12,Kka2,kka2_1:4,P00552,0.845992,NO,12,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.853,-5.545,4.692,,,,B,0.52,1.25,0.843,,48.11,POH,-1.80767,0.168804,0.00500011,0.845992 kka2_1:1_L7M,kka2_1:1_7,Kka2,kka2_1:1,P00552,0.846004,NO,7,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.926,-2.658,0.732,,,,,,,18.934,18.934,71.59,OHB,-2.12333,0.520039,0.00269456,0.846004 beta-lactamase_2500_L55R,beta-lactamase_2500_55,TEM-1,beta-lactamase_2500,P62593,0.846041,NO,55,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.86,-3.1,1.24,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.361275,0.00403741,0.846041 beta-lactamase_625_P105G,beta-lactamase_625_105,TEM-1,beta-lactamase_625,P62593,0.84605,NO,105,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.813,-3.321,2.508,,0.226,T,A,0.52,0.8,1.154,,63.29,POH,-1.01533,0.213352,0.0011981,0.84605 kka2_1:8_L57E,kka2_1:8_57,Kka2,kka2_1:8,P00552,0.846117,NO,57,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.898,-3.855,1.957,,0.343,T,A,0.55,0.98,13.359,13.359,52.65,HHP,-2.20733,0.100394,0.00723769,0.846117 kka2_1:8_L57E,kka2_1:8_57,Kka2,kka2_1:8,P00552,0.846117,NO,57,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.898,-3.855,1.957,,0.343,T,A,0.55,0.98,13.359,13.359,52.65,HHP,-2.20733,0.100394,0.00723769,0.846117 beta-lactamase_Y260V,beta-lactamase_260,TEM-1,beta-lactamase,P62593,0.846153,NO,260,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-1.101,-3.316,2.215,5.50878,,E,B,0.73,-1.04,0.865,,60.49,HHP,-1.83433,0.221079,0.00471757,0.846153 kka2_1:4_P132T,kka2_1:4_132,Kka2,kka2_1:4,P00552,0.846161,NO,132,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.775,-3.417,2.642,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.168804,0.0018489,0.846161 beta-lactamase_I140T,beta-lactamase_140,TEM-1,beta-lactamase,P62593,0.846164,NO,140,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.733,-2.748,1.015,5.29918,0.128,H,A,1,0.41,1.16,,73.08,PHO,-1.48733,0.221079,0.00597777,0.846164 beta-lactamase_39_M115W,beta-lactamase_39_115,TEM-1,beta-lactamase_39,P62593,0.846209,NO,115,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.389,-5.031,3.642,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.0495842,0.0034337,0.846209 beta-lactamase_156_P65F,beta-lactamase_156_65,TEM-1,beta-lactamase_156,P62593,0.84625,NO,65,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.894,-4.306,3.412,,0.098,E,B,0.52,-0.62,0.623,,40.56,HOH,-1.03233,0.111618,0.00152776,0.84625 kka2_1:2_N195S,kka2_1:2_195,Kka2,kka2_1:2,P00552,0.846278,NO,195,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-0.836,-3.008,2.172,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.295029,0.00276134,0.846278 kka2_1:1_L170P,kka2_1:1_170,Kka2,kka2_1:1,P00552,0.846339,NO,170,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.28,-4.106,2.826,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.520039,0.00730791,0.846339 kka2_1:4_H124P,kka2_1:4_124,Kka2,kka2_1:4,P00552,0.84634,NO,124,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-0.84,-3.908,3.068,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.168804,0.00211296,0.84634 beta-lactamase_E35A,beta-lactamase_35,TEM-1,beta-lactamase,P62593,0.846342,NO,35,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-0.869,-3.127,2.258,5.10723,0.15,H,A,0.52,0.21,1.081,,46.85,HAA,-1.88667,0.221079,0.00174441,0.846342 gb1_T237K,gb1_237,gb1,gb1,P06654,0.846408,NO,237,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.736,-3.282,1.546,,,,,,,0.218,,11.83,BPH,-2.27833,0.177985,0.00275316,0.846408 beta-lactamase_0_K254M,beta-lactamase_0_254,TEM-1,beta-lactamase_0,P62593,0.846411,NO,254,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.0500837,0.00369,0.846411 kka2_1:8_G245K,kka2_1:8_245,Kka2,kka2_1:8,P00552,0.846432,NO,245,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.812,-3.635,2.823,,0.655,T,g,0.75,0.03,1.148,,65.53,HOH,-1.19833,0.100394,0.00683899,0.846432 kka2_1:8_G245K,kka2_1:8_245,Kka2,kka2_1:8,P00552,0.846432,NO,245,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.812,-3.635,2.823,,0.655,T,g,0.75,0.03,1.148,,65.53,HOH,-1.19833,0.100394,0.00683899,0.846432 kka2_1:2_L193R,kka2_1:2_193,Kka2,kka2_1:2,P00552,0.846456,NO,193,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.983,-3.937,2.954,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.295029,0.00480179,0.846456 beta-lactamase_0_D207Y,beta-lactamase_0_207,TEM-1,beta-lactamase_0,P62593,0.846478,NO,207,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.064,-4.317,2.253,,0.409,H,A,0.75,0.12,5.277,,77.62,HAH,-1.77033,0.0500837,0.00592942,0.846478 beta-lactamase_156_T69A,beta-lactamase_156_69,TEM-1,beta-lactamase_156,P62593,0.84649,NO,69,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-0.973,-2.115,1.142,,,G,A,0.22,-1.24,4.194,,93.01,PPH,-1.01833,0.111618,0.00127498,0.84649 kka2_1:4_K112T,kka2_1:4_112,Kka2,kka2_1:4,P00552,0.846508,NO,112,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-2.491,-2.629,0.138,,0.076,H,A,2.34,-1.37,0.39,,56.06,ABH,-2.00133,0.168804,0.00645389,0.846508 beta-lactamase_2500_L197M,beta-lactamase_2500_197,TEM-1,beta-lactamase_2500,P62593,0.846518,NO,197,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.853,-3.888,3.035,,0.007,S,B,0.55,0.33,2.421,,60.14,HHP,-1.833,0.361275,0.00144602,0.846518 kka2_1:4_G74L,kka2_1:4_74,Kka2,kka2_1:4,P00552,0.84658,NO,74,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.18,-3.872,2.692,,0.621,T,l,0.75,0.2,1.032,,64.39,POH,-1.91667,0.168804,0.00587035,0.84658 beta-lactamase_0_T69K,beta-lactamase_0_69,TEM-1,beta-lactamase_0,P62593,0.84664,NO,69,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-0.973,-3.493,2.52,,,G,A,0.22,-1.24,0.505,,93.01,PPH,-1.01833,0.0500837,0.00127498,0.84664 beta-lactamase_0_T198W,beta-lactamase_0_198,TEM-1,beta-lactamase_0,P62593,0.846649,NO,198,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.168,-5.419,3.251,,0.489,,B,0.22,-0.13,9.874,,73.78,HPH,-1.98767,0.0500837,0.004311,0.846649 beta-lactamase_0_L79N,beta-lactamase_0_79,TEM-1,beta-lactamase_0,P62593,0.846667,NO,79,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.842,-4.12,3.278,,0.007,H,A,0.55,-0.16,5.053,,50.35,HHP,-1.44333,0.0500837,0.000947397,0.846667 beta-lactamase_0_A133H,beta-lactamase_0_133,TEM-1,beta-lactamase_0,P62593,0.846677,NO,133,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.186,-4.769,3.583,,,H,A,0.46,-0.86,2.148,,67.83,HHP,-0.988333,0.0500837,0.00468022,0.846677 beta-lactamase_0_Y103Q,beta-lactamase_0_103,TEM-1,beta-lactamase_0,P62593,0.846698,NO,103,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-1.33,-2.924,1.594,,0.613,S,l,0.21,1.21,1.646,,63.29,AHP,-1.48767,0.0500837,0.00443048,0.846698 kka2_1:8_V80W,kka2_1:8_80,Kka2,kka2_1:8,P00552,0.846746,NO,80,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.144,-5.458,4.314,,0.358,E,B,1.48,-0.24,2.562,,63.64,HHH,-1.64633,0.100394,0.00488211,0.846746 kka2_1:8_V80W,kka2_1:8_80,Kka2,kka2_1:8,P00552,0.846746,NO,80,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.144,-5.458,4.314,,0.358,E,B,1.48,-0.24,2.562,,63.64,HHH,-1.64633,0.100394,0.00488211,0.846746 beta-lactamase_I125T,beta-lactamase_125,TEM-1,beta-lactamase,P62593,0.846766,NO,125,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.441,-2.752,1.311,5.23481,,H,A,2.82,-0.7,2.301,,63.29,HHP,-1.248,0.221079,0.00383964,0.846766 beta-lactamase_R91Q,beta-lactamase_91,TEM-1,beta-lactamase,P62593,0.846766,NO,91,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.392,-2.363,0.971,5.92536,0.444,,B,0.68,0.96,1.318,,50.35,OBB,-1.73367,0.221079,0.00380226,0.846766 kka2_1:4_L259A,kka2_1:4_259,Kka2,kka2_1:4,P00552,0.846767,NO,259,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.088,-2.512,1.424,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.168804,0.0206964,0.846767 Ubiquitin_D24K,Ubiquitin_24,Uba1,Ubiquitin,P0CG48,0.846774,NO,24,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,,,,,,,,,,,,,HAP,,0.205827,0.0066591,0.846774 Ubiquitin_E34K,Ubiquitin_34,Uba1,Ubiquitin,P0CG48,0.846774,NO,34,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.294,-2.308,1.014,5.02178,0.406,H,A,1.62,0.6,1.295,,35.62,BAO,-1.24933,0.205827,0.000686048,0.846774 Ubiquitin_G35I,Ubiquitin_35,Uba1,Ubiquitin,P0CG48,0.846774,NO,35,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.171,-3.79,2.619,4.96213,0.713,,L,,0.2,,,,AOH,-1.314,0.205827,0.000648878,0.846774 Ubiquitin_I13R,Ubiquitin_13,Uba1,Ubiquitin,P0CG48,0.846774,NO,13,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.554,-4.029,2.475,5.19411,0.038,E,B,,-0.2,,,,PHP,-1.48,0.205827,0.000716423,0.846774 Ubiquitin_K27H,Ubiquitin_27,Uba1,Ubiquitin,P0CG48,0.846774,NO,27,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.064,-4.448,3.384,4.77438,0.086,H,A,2.89,-0.74,2.662,,27.01,HBH,-1.42667,0.205827,0.000767556,0.846774 Ubiquitin_K6M,Ubiquitin_6,Uba1,Ubiquitin,P0CG48,0.846774,NO,6,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.093,-4.53,3.437,4.84211,0.35,E,B,1.82,-0.62,1.502,,71.82,HBP,-1.36133,0.205827,0.000784795,0.846774 Ubiquitin_L43C,Ubiquitin_43,Uba1,Ubiquitin,P0CG48,0.846774,NO,43,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.269,-4.759,3.49,4.8799,,E,B,1.75,-1.17,10.246,10.246,53.87,BHH,-1.46867,0.205827,0.000572481,0.846774 Ubiquitin_Q40C,Ubiquitin_40,Uba1,Ubiquitin,P0CG48,0.846774,NO,40,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-1.752,-5.118,3.366,4.7807,0.387,G,A,,0.03,,,,APP,-1.62433,0.205827,0.000619089,0.846774 Ubiquitin_Q40K,Ubiquitin_40,Uba1,Ubiquitin,P0CG48,0.846774,NO,40,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-1.752,-2.704,0.952,4.7807,0.387,G,A,,0.03,,,,APP,-1.62433,0.205827,0.000619089,0.846774 Ubiquitin_Q40L,Ubiquitin_40,Uba1,Ubiquitin,P0CG48,0.846774,NO,40,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-1.752,-3.457,1.705,4.7807,0.387,G,A,,0.03,,,,APP,-1.62433,0.205827,0.000619089,0.846774 Ubiquitin_Q49H,Ubiquitin_49,Uba1,Ubiquitin,P0CG48,0.846774,NO,49,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-1.941,-3.211,1.27,5.05026,0.403,E,B,,-0.59,,,,BPH,-1.49467,0.205827,0.000613067,0.846774 Ubiquitin_T22W,Ubiquitin_22,Uba1,Ubiquitin,P0CG48,0.846774,NO,22,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.344,-5.275,3.931,4.54389,0.237,B,B,,-0.75,,,,APH,-1.28733,0.205827,0.000535592,0.846774 Ubiquitin_T66V,Ubiquitin_66,Uba1,Ubiquitin,P0CG48,0.846774,NO,66,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.58,-2.736,1.156,5.02702,0.46,E,B,0.8,-0.81,28.36,28.36,39.71,PPH,-1.51667,0.205827,0.000598414,0.846774 beta-lactamase_0_L146R,beta-lactamase_0_146,TEM-1,beta-lactamase_0,P62593,0.846813,NO,146,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.462,-4.192,2.73,,0.007,H,A,0.55,-0.56,2.051,,64.69,AHP,-1.656,0.0500837,0.00474542,0.846813 beta-lactamase_0_L191E,beta-lactamase_0_191,TEM-1,beta-lactamase_0,P62593,0.84683,NO,191,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.087,-3.859,2.772,,,H,A,0.55,0.09,12.255,12.255,63.29,BHH,-1.445,0.0500837,0.00263549,0.84683 kka2_1:8_K112R,kka2_1:8_112,Kka2,kka2_1:8,P00552,0.84693,NO,112,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-2.491,-2.2,-0.291,,0.076,H,A,1.3,-1.37,10.58,10.58,56.06,ABH,-2.00133,0.100394,0.00645389,0.84693 kka2_1:8_K112R,kka2_1:8_112,Kka2,kka2_1:8,P00552,0.84693,NO,112,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-2.491,-2.2,-0.291,,0.076,H,A,1.3,-1.37,10.58,10.58,56.06,ABH,-2.00133,0.100394,0.00645389,0.84693 beta-lactamase_0_L160W,beta-lactamase_0_160,TEM-1,beta-lactamase_0,P62593,0.846931,NO,160,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.977,-5.194,4.217,,0.022,,B,0.55,-0.6,0.68,,44.41,BHA,-0.936,0.0500837,0.00193775,0.846931 beta-lactamase_0_E56Y,beta-lactamase_0_56,TEM-1,beta-lactamase_0,P62593,0.846941,NO,56,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.043,-4.216,2.173,,0.198,E,B,1.04,0.31,1.491,,72.73,HAP,-1.94033,0.0500837,0.00238534,0.846941 beta-lactamase_0_S221H,beta-lactamase_0_221,TEM-1,beta-lactamase_0,P62593,0.846969,NO,221,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.754,-4.673,2.919,,0.624,H,A,0.27,-0.2,2.914,,74.48,BPH,-1.59967,0.0500837,0.0046094,0.846969 beta-lactamase_0_L111C,beta-lactamase_0_111,TEM-1,beta-lactamase_0,P62593,0.847057,NO,111,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.76,-4.796,3.036,,0.328,T,A,0.55,0.93,1.966,,64.34,BHP,-1.884,0.0500837,0.00480671,0.847057 kka2_1:4_A191T,kka2_1:4_191,Kka2,kka2_1:4,P00552,0.847063,NO,191,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.831,-3.288,2.457,,,.,b,0.46,-0.94,2.046,,50,AHO,-0.868667,0.168804,0.00338807,0.847063 beta-lactamase_D212G,beta-lactamase_212,TEM-1,beta-lactamase,P62593,0.847074,NO,212,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.624,-2.198,0.574,4.9705,0.037,,b,1.3,-0.58,12.482,,74.48,HAB,-1.77667,0.221079,0.00644302,0.847074 PSD95pdz3_E373M,PSD95pdz3_373,PSD95pdz3,PSD95pdz3,P31016,0.847106,NO,373,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.404,-4.387,2.983,5.79743,,,,,27.9833,,,,BAP,-1.57667,0.0758425,0.000387698,0.847106 beta-lactamase_E102C,beta-lactamase_102,TEM-1,beta-lactamase,P62593,0.847131,NO,102,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.118,-5.064,2.946,6.36157,0.722,S,B,1.5,1.82,1.336,,73.08,HAH,-1.581,0.221079,0.00486633,0.847131 beta-lactamase_L55W,beta-lactamase_55,TEM-1,beta-lactamase,P62593,0.847131,NO,55,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.86,-2.099,0.239,,0.372,E,A,1.07,-0.36,1.423,,63.99,HHA,-2.247,0.221079,0.00403741,0.847131 beta-lactamase_0_E169T,beta-lactamase_0_169,TEM-1,beta-lactamase_0,P62593,0.847234,NO,169,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.23,-2.43,1.2,,0.337,,A,1.04,1,3.516,,73.08,PAH,-1.16533,0.0500837,0.00400994,0.847234 Pab1_D138R,Pab1_138,Pab1,Pab1,P04147,0.847237,NO,138,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.128,-3.673,2.545,,0.427,,B,,-0.03,,,,HAP,-1.13967,0.175299,0.000567877,0.847237 gb1_T237F,gb1_237,gb1,gb1,P06654,0.847242,NO,237,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.736,-4.029,2.293,,,,,,,0.218,,11.83,BPH,-2.27833,0.177985,0.00275316,0.847242 beta-lactamase_0_E26H,beta-lactamase_0_26,TEM-1,beta-lactamase_0,P62593,0.847287,NO,26,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.454,-4.609,2.155,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.0500837,0.00297948,0.847287 kka2_1:4_G201C,kka2_1:4_201,Kka2,kka2_1:4,P00552,0.847357,NO,201,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.56,-3.58,2.02,,0.149,T,l,0.29,-0.57,0.284,,52.65,POB,-1.92233,0.168804,0.00820117,0.847357 beta-lactamase_A230I,beta-lactamase_230,TEM-1,beta-lactamase,P62593,0.847372,NO,230,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.154,-3.843,2.689,4.54336,0.01,E,B,0.75,-1.17,1.97,,50,HHA,-1.079,0.221079,0.00516841,0.847372 beta-lactamase_0_L248E,beta-lactamase_0_248,TEM-1,beta-lactamase_0,P62593,0.847386,NO,248,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.0500837,0.00428493,0.847386 beta-lactamase_0_R257A,beta-lactamase_0_257,TEM-1,beta-lactamase_0,P62593,0.847451,NO,257,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.0500837,0.00756629,0.847451 kka2_1:4_E199G,kka2_1:4_199,Kka2,kka2_1:4,P00552,0.847478,NO,199,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.234,-3.518,1.284,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.168804,0.00854122,0.847478 beta-lactamase_D161H,beta-lactamase_161,TEM-1,beta-lactamase,P62593,0.847518,NO,161,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.891,-4.479,3.588,5.12208,0.341,,A,0.23,-0.52,1.602,,61.19,HAB,-0.961333,0.221079,0.000897697,0.847518 beta-lactamase_0_T69E,beta-lactamase_0_69,TEM-1,beta-lactamase_0,P62593,0.847533,NO,69,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-0.973,-3.476,2.503,,,G,A,0.22,-1.24,0.505,,93.01,PPH,-1.01833,0.0500837,0.00127498,0.847533 beta-lactamase_0_R257V,beta-lactamase_0_257,TEM-1,beta-lactamase_0,P62593,0.847583,NO,257,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.533,-4.11,2.577,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.0500837,0.00756629,0.847583 kka2_1:8_L60G,kka2_1:8_60,Kka2,kka2_1:8,P00552,0.847584,NO,60,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.997,-3.865,2.868,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.100394,0.00262176,0.847584 kka2_1:8_L60G,kka2_1:8_60,Kka2,kka2_1:8,P00552,0.847584,NO,60,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.997,-3.865,2.868,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.100394,0.00262176,0.847584 beta-lactamase_0_L146V,beta-lactamase_0_146,TEM-1,beta-lactamase_0,P62593,0.847606,NO,146,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.462,-1.839,0.377,,0.007,H,A,0.55,-0.56,2.051,,64.69,AHP,-1.656,0.0500837,0.00474542,0.847606 beta-lactamase_2500_K286I,beta-lactamase_2500_286,TEM-1,beta-lactamase_2500,P62593,0.847632,NO,286,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.361275,,0.847632 beta-lactamase_0_L191F,beta-lactamase_0_191,TEM-1,beta-lactamase_0,P62593,0.847638,NO,191,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.087,-2.754,1.667,,,H,A,0.55,0.09,12.255,12.255,63.29,BHH,-1.445,0.0500837,0.00263549,0.847638 kka2_1:2_H139G,kka2_1:2_139,Kka2,kka2_1:2,P00552,0.847655,NO,139,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-2.809,-2.92,0.111,,0.471,H,A,0.87,0.68,13.912,13.912,63.64,BBB,-2.22,0.295029,0.00734779,0.847655 kka2_1:2_I246A,kka2_1:2_246,Kka2,kka2_1:2,P00552,0.847668,NO,246,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-2.008,-2.246,0.238,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.295029,0.0139479,0.847668 beta-lactamase_39_S104W,beta-lactamase_39_104,TEM-1,beta-lactamase_39,P62593,0.847672,NO,104,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.015,-5.359,4.344,,0.04,,b,0.27,0.57,4.02,,63.29,HPO,-1.05267,0.0495842,0.00218083,0.847672 beta-lactamase_156_E195L,beta-lactamase_156_195,TEM-1,beta-lactamase_156,P62593,0.847708,NO,195,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.186,-3.741,1.555,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.111618,0.00496565,0.847708 beta-lactamase_V106N,beta-lactamase_106,TEM-1,beta-lactamase,P62593,0.847726,NO,106,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.218,-4.217,2.999,5.23115,0.258,T,A,0.96,0.24,1.188,,72.73,OHP,-1.04933,0.221079,0.00304168,0.847726 beta-lactamase_A183L,beta-lactamase_183,TEM-1,beta-lactamase,P62593,0.847823,NO,183,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.231,-3.283,2.052,4.84712,0.155,H,A,0.55,-0.91,12.189,,77.62,HHH,-1.53367,0.221079,0.00296631,0.847823 kka2_1:4_D127A,kka2_1:4_127,Kka2,kka2_1:4,P00552,0.847825,NO,127,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.364,-2.492,1.128,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.168804,0.00660501,0.847825 kka2_1:4_D227T,kka2_1:4_227,Kka2,kka2_1:4,P00552,0.847874,NO,227,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.758,-3.153,1.395,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.168804,0.00745029,0.847874 beta-lactamase_0_I125D,beta-lactamase_0_125,TEM-1,beta-lactamase_0,P62593,0.847902,NO,125,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.441,-3.998,2.557,,,H,A,0.48,-0.7,1.874,,63.29,HHP,-1.248,0.0500837,0.00383964,0.847902 beta-lactamase_625_A40I,beta-lactamase_625_40,TEM-1,beta-lactamase_625,P62593,0.847933,NO,40,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.402,-3.742,2.34,,0.155,S,B,0.46,0.21,1.357,,73.78,OHB,-1.40267,0.213352,0.00490026,0.847933 beta-lactamase_P143T,beta-lactamase_143,TEM-1,beta-lactamase,P62593,0.84794,NO,143,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.967,-2.616,1.649,5.16366,0.075,H,A,0.99,-0.37,0.479,,66.78,OOB,-1.354,0.221079,0.00114551,0.84794 beta-lactamase_0_K71L,beta-lactamase_0_71,TEM-1,beta-lactamase_0,P62593,0.847949,NO,71,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-0.8,-3.358,2.558,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.0500837,0.00103192,0.847949 beta-lactamase_156_A40R,beta-lactamase_156_40,TEM-1,beta-lactamase_156,P62593,0.848029,NO,40,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.402,-3.924,2.522,,0.155,S,B,0.46,0.21,1.357,,73.78,OHB,-1.40267,0.111618,0.00490026,0.848029 kka2_1:4_R173S,kka2_1:4_173,Kka2,kka2_1:4,P00552,0.848043,NO,173,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.407,-3.482,1.075,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.168804,0.00784999,0.848043 beta-lactamase_R159V,beta-lactamase_159,TEM-1,beta-lactamase,P62593,0.848049,NO,159,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-0.94,-3.779,2.839,5.64971,0.316,,B,0.68,-0.55,1.172,,64.34,PBH,-1.011,0.221079,0.00108472,0.848049 beta-lactamase_0_L111M,beta-lactamase_0_111,TEM-1,beta-lactamase_0,P62593,0.848053,NO,111,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.76,-4.22,2.46,,0.328,T,A,0.55,0.93,1.966,,64.34,BHP,-1.884,0.0500837,0.00480671,0.848053 beta-lactamase_G52S,beta-lactamase_52,TEM-1,beta-lactamase,P62593,0.848065,NO,52,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.149,-2.647,1.498,5.12093,0.299,,l,0.77,-0.04,2.103,,64.69,POB,-1.66267,0.221079,0.00340138,0.848065 beta-lactamase_T147L,beta-lactamase_147,TEM-1,beta-lactamase,P62593,0.848082,NO,147,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.149,-3.242,2.093,5.37474,0.281,H,A,0.8,-0.68,2.838,,64.34,HPH,-1.456,0.221079,0.00226017,0.848082 beta-lactamase_F58K,beta-lactamase_58,TEM-1,beta-lactamase,P62593,0.848108,NO,58,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-2.914,-3.623,0.709,5.55634,0.266,E,B,1.33,-0.07,2.467,,77.62,PHB,-2.059,0.221079,0.00523369,0.848108 kka2_1:4_F206Y,kka2_1:4_206,Kka2,kka2_1:4,P00552,0.848145,NO,206,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.349,-1.759,0.41,,0.006,E,B,0.58,-1.21,1.342,,63.64,OHH,-1.04,0.168804,0.00936868,0.848145 beta-lactamase_2500_R91N,beta-lactamase_2500_91,TEM-1,beta-lactamase_2500,P62593,0.848178,NO,91,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.392,-3.596,2.204,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.361275,0.00380226,0.848178 beta-lactamase_G263H,beta-lactamase_263,TEM-1,beta-lactamase,P62593,0.848193,NO,263,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-2.031,-4.569,2.538,5.09799,0.517,S,l,0.77,0.31,16.425,16.425,77.62,POP,-1.78267,0.221079,0.0110582,0.848193 beta-lactamase_G263R,beta-lactamase_263,TEM-1,beta-lactamase,P62593,0.848201,NO,263,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-2.031,-2.757,0.726,5.09799,0.517,S,l,0.77,0.31,16.425,16.425,77.62,POP,-1.78267,0.221079,0.0110582,0.848201 beta-lactamase_R176T,beta-lactamase_176,TEM-1,beta-lactamase,P62593,0.848208,NO,176,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-0.863,-3.421,2.558,5.61264,0.385,T,B,0.68,-0.63,,,,ABA,-1.38867,0.221079,0.00105554,0.848208 beta-lactamase_F70S,beta-lactamase_70,TEM-1,beta-lactamase,P62593,0.848225,NO,70,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.169,-2.713,1.544,5.42055,,H,A,1.1,-1.34,1.14,,63.99,PHB,-0.980667,0.221079,0.00193499,0.848225 kka2_1:1_A255G,kka2_1:1_255,Kka2,kka2_1:1,P00552,0.848246,NO,255,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.715,-2.509,0.794,,0.466,H,A,0.46,-0.52,0.946,,65.53,HHH,-1.71267,0.520039,0.0126809,0.848246 beta-lactamase_2500_V82H,beta-lactamase_2500_82,TEM-1,beta-lactamase_2500,P62593,0.848282,NO,82,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.325,-4.872,3.547,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.361275,0.00397046,0.848282 kka2_1:4_L94Q,kka2_1:4_94,Kka2,kka2_1:4,P00552,0.848365,NO,94,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.618,-4.05,2.432,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.168804,0.00520888,0.848365 kka2_1:4_L184R,kka2_1:4_184,Kka2,kka2_1:4,P00552,0.848389,NO,184,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.496,-2.591,1.095,,0.489,E,B,1.59,-0.06,4.495,,63.26,AHH,-1.24833,0.168804,0.00518742,0.848389 kka2_1:8_E182D,kka2_1:8_182,Kka2,kka2_1:8,P00552,0.848393,NO,182,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.516,-2.787,1.271,,0.326,,B,1.52,0.75,2.568,,65.53,OAA,-1.806,0.100394,0.00641548,0.848393 kka2_1:8_E182D,kka2_1:8_182,Kka2,kka2_1:8,P00552,0.848393,NO,182,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.516,-2.787,1.271,,0.326,,B,1.52,0.75,2.568,,65.53,OAA,-1.806,0.100394,0.00641548,0.848393 beta-lactamase_2500_P217R,beta-lactamase_2500_217,TEM-1,beta-lactamase_2500,P62593,0.848412,NO,217,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-2.062,-3.069,1.007,,0.496,I,A,0.52,-0.33,0.431,,74.48,OOH,-1.64333,0.361275,0.00463211,0.848412 Pab1_S155T,Pab1_155,Pab1,Pab1,P04147,0.848414,NO,155,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.039,-3.173,1.134,,,,,,,,,,PPB,-1.42267,0.175299,0.00208179,0.848414 gb1_T242Y,gb1_242,gb1,gb1,P06654,0.848485,NO,242,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.245,-3.898,2.653,,,,,,,,,,APP,-1.444,0.177985,0.00243886,0.848485 beta-lactamase_0_A246V,beta-lactamase_0_246,TEM-1,beta-lactamase_0,P62593,0.8485,NO,246,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.121,-1.76,-0.361,,0.01,E,B,0.46,-1.01,1.201,,73.78,HHH,-1.55633,0.0500837,0.00569458,0.8485 kka2_1:2_A129V,kka2_1:2_129,Kka2,kka2_1:2,P00552,0.848511,NO,129,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.656,-3.024,1.368,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.295029,0.00726862,0.848511 kka2_1:8_F264L,kka2_1:8_264,Kka2,kka2_1:8,P00552,0.848523,NO,264,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.02,-2.468,1.448,,0.296,,?,1.62,0.02,1.553,,71.59,HHO,-0.9655,0.100394,,0.848523 kka2_1:8_F264L,kka2_1:8_264,Kka2,kka2_1:8,P00552,0.848523,NO,264,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.02,-2.468,1.448,,0.296,,?,1.62,0.02,1.553,,71.59,HHO,-0.9655,0.100394,,0.848523 kka2_1:4_A56N,kka2_1:4_56,Kka2,kka2_1:4,P00552,0.848543,NO,56,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.083,-3.917,1.834,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.168804,0.00717715,0.848543 kka2_1:8_D90A,kka2_1:8_90,Kka2,kka2_1:8,P00552,0.848549,NO,90,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.459,-3.423,0.964,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.100394,0.00583842,0.848549 kka2_1:8_D90A,kka2_1:8_90,Kka2,kka2_1:8,P00552,0.848549,NO,90,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.459,-3.423,0.964,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.100394,0.00583842,0.848549 kka2_1:1_R239L,kka2_1:1_239,Kka2,kka2_1:1,P00552,0.848575,NO,239,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.949,-2.571,-0.378,,0.15,H,A,1.2,-0.31,0.477,,71.59,ABH,-2.23,0.520039,0.00835326,0.848575 kka2_1:1_L193D,kka2_1:1_193,Kka2,kka2_1:1,P00552,0.848577,NO,193,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.983,-4.051,3.068,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.520039,0.00480179,0.848577 beta-lactamase_0_G52Q,beta-lactamase_0_52,TEM-1,beta-lactamase_0,P62593,0.848591,NO,52,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.149,-2.995,1.846,,0.299,,l,0.29,-0.04,1.164,,64.69,POB,-1.66267,0.0500837,0.00340138,0.848591 kka2_1:8_L94R,kka2_1:8_94,Kka2,kka2_1:8,P00552,0.848654,NO,94,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.618,-3.994,2.376,,0.058,E,B,1.59,-0.52,2.197,,56.06,HHO,-1.612,0.100394,0.00520888,0.848654 kka2_1:8_L94R,kka2_1:8_94,Kka2,kka2_1:8,P00552,0.848654,NO,94,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.618,-3.994,2.376,,0.058,E,B,1.59,-0.52,2.197,,56.06,HHO,-1.612,0.100394,0.00520888,0.848654 beta-lactamase_625_H24P,beta-lactamase_625_24,TEM-1,beta-lactamase_625,P62593,0.848677,NO,24,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-2.481,-3.827,1.346,,,,,,,2.708,,93.01,OBO,-2.0035,0.213352,0.00238894,0.848677 beta-lactamase_0_P224A,beta-lactamase_0_224,TEM-1,beta-lactamase_0,P62593,0.848719,NO,224,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.893,-3.071,2.178,,0.383,,B,0.52,-0.3,3.587,,74.48,HOH,-1.26433,0.0500837,0.00189564,0.848719 beta-lactamase_2500_G265E,beta-lactamase_2500_265,TEM-1,beta-lactamase_2500,P62593,0.84876,NO,265,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.361275,0.00811926,0.84876 beta-lactamase_0_D174E,beta-lactamase_0_174,TEM-1,beta-lactamase_0,P62593,0.848797,NO,174,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.738,-2.765,2.027,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.0500837,0.00125633,0.848797 beta-lactamase_L223K,beta-lactamase_223,TEM-1,beta-lactamase,P62593,0.84885,NO,223,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.055,-3.742,2.687,5.42318,0.27,,B,1.3,0.09,1.511,,74.48,HHO,-1.35033,0.221079,0.00372793,0.84885 kka2_1:2_L126M,kka2_1:2_126,Kka2,kka2_1:2,P00552,0.848852,NO,126,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.246,-4.129,2.883,,0.285,S,B,0.55,0.12,1.392,,51.89,PHA,-1.744,0.295029,0.0066485,0.848852 beta-lactamase_625_G76V,beta-lactamase_625_76,TEM-1,beta-lactamase_625,P62593,0.848881,NO,76,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.189,-3.485,2.296,,,H,A,0.29,-0.67,3.059,,67.83,OOH,-1.22267,0.213352,0.00476637,0.848881 beta-lactamase_2500_A235S,beta-lactamase_2500_235,TEM-1,beta-lactamase_2500,P62593,0.848883,NO,235,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.266,-2.058,0.792,,0.32,E,B,0.46,-0.86,0.891,,50,OHO,-0.89,0.361275,0.00493474,0.848883 gb1_L231N,gb1_231,gb1,gb1,P06654,0.848897,NO,231,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.603,-3.815,2.212,,,,,,,0.219,,11.83,BHH,-1.82633,0.177985,0.00322797,0.848897 gb1_T237V,gb1_237,gb1,gb1,P06654,0.848897,NO,237,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.736,-3.248,1.512,,,,,,,0.218,,11.83,BPH,-2.27833,0.177985,0.00275316,0.848897 gb1_T242F,gb1_242,gb1,gb1,P06654,0.848897,NO,242,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.245,-3.803,2.558,,,,,,,,,,APP,-1.444,0.177985,0.00243886,0.848897 beta-lactamase_F70G,beta-lactamase_70,TEM-1,beta-lactamase,P62593,0.84894,NO,70,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.169,-3.574,2.405,5.42055,,H,A,1.1,-1.34,1.14,,63.99,PHB,-0.980667,0.221079,0.00193499,0.84894 hsp90_F583C,hsp90_583,hsp90,hsp90,P02829,0.848963,NO,583,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-3.22,-4.015,0,5.28185,1.112,S,l,1.1,0.87,,,,PHO,-3.003,0.368192,0.000222939,0.848963 beta-lactamase_0_H287S,beta-lactamase_0_287,TEM-1,beta-lactamase_0,P62593,0.849007,NO,287,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,,,,,,,,,,,,,BBH,-1.111,0.0500837,,0.849007 beta-lactamase_P165M,beta-lactamase_165,TEM-1,beta-lactamase,P62593,0.84901,NO,165,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.373,-4.649,3.276,5.33889,0.203,T,A,0.99,-0.31,0.414,,73.78,AOA,-1.359,0.221079,0.00549538,0.84901 beta-lactamase_T198F,beta-lactamase_198,TEM-1,beta-lactamase,P62593,0.84901,NO,198,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.168,-4.258,2.09,4.9209,0.489,,B,0.69,-0.13,0.37,,73.78,HPH,-1.98767,0.221079,0.004311,0.84901 beta-lactamase_V214R,beta-lactamase_214,TEM-1,beta-lactamase,P62593,0.84901,NO,214,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.299,-4.047,2.748,5.74008,0.375,S,A,1.19,-0.44,1.899,,74.48,BHH,-1.53733,0.221079,0.00628442,0.84901 beta-lactamase_2500_H287G,beta-lactamase_2500_287,TEM-1,beta-lactamase_2500,P62593,0.849082,NO,287,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,,,,,,,,,,,,,BBH,-1.111,0.361275,,0.849082 kka2_1:1_A34S,kka2_1:1_34,Kka2,kka2_1:1,P00552,0.849121,NO,34,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.928,-1.892,0.964,,0.417,.,B,0.46,2.29,0.262,,52.27,AHH,-1.747,0.520039,0.00343484,0.849121 kka2_1:4_F264L,kka2_1:4_264,Kka2,kka2_1:4,P00552,0.849197,NO,264,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.02,-2.468,1.448,,0.296,,?,1.62,0.02,1.93,,71.59,HHO,-0.9655,0.168804,,0.849197 beta-lactamase_0_G234K,beta-lactamase_0_234,TEM-1,beta-lactamase_0,P62593,0.849283,NO,234,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.62,-3.682,3.062,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.0500837,0.000889577,0.849283 kka2_1:4_L152W,kka2_1:4_152,Kka2,kka2_1:4,P00552,0.849335,NO,152,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.521,-5.416,3.895,,0.547,,A,1.59,1.36,2.318,,63.64,OHH,-1.162,0.168804,0.00674868,0.849335 beta-lactamase_0_L38Q,beta-lactamase_0_38,TEM-1,beta-lactamase_0,P62593,0.849351,NO,38,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.343,-4.155,2.812,,0.088,H,A,0.55,0.2,13.556,13.556,64.34,PHO,-1.78033,0.0500837,0.00373244,0.849351 beta-lactamase_S2D,beta-lactamase_2,TEM-1,beta-lactamase,P62593,0.849352,NO,2,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.942,-3.437,1.495,,,,,,,2.36,,65.38,HPH,-2.02767,0.221079,0.00227352,0.849352 beta-lactamase_L160Q,beta-lactamase_160,TEM-1,beta-lactamase,P62593,0.849364,NO,160,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.977,-4.199,3.222,5.32068,0.022,,B,1.75,-0.6,0.895,,44.41,BHA,-0.936,0.221079,0.00193775,0.849364 kka2_1:1_V46P,kka2_1:1_46,Kka2,kka2_1:1,P00552,0.849425,NO,46,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-2.62,-2.348,-0.272,,0.192,.,B,0.44,-1.12,20.149,20.149,92.05,OHH,-1.88633,0.520039,0.00631301,0.849425 beta-lactamase_0_S104K,beta-lactamase_0_104,TEM-1,beta-lactamase_0,P62593,0.84943,NO,104,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.015,-3.372,2.357,,0.04,,b,0.27,0.57,1.148,,63.29,HPO,-1.05267,0.0500837,0.00218083,0.84943 kka2_1:1_A56H,kka2_1:1_56,Kka2,kka2_1:1,P00552,0.849493,NO,56,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.083,-4.875,2.792,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.520039,0.00717715,0.849493 beta-lactamase_F149R,beta-lactamase_149,TEM-1,beta-lactamase,P62593,0.849547,NO,149,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.299,-4.139,2.84,5.54789,0.195,H,A,1.1,0.11,1.863,,63.99,HHH,-1.46067,0.221079,0.00418462,0.849547 kka2_1:2_H188Q,kka2_1:2_188,Kka2,kka2_1:2,P00552,0.849623,NO,188,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-0.913,-2.723,1.81,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.295029,0.00273139,0.849623 kka2_1:8_G233V,kka2_1:8_233,Kka2,kka2_1:8,P00552,0.849642,NO,233,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.748,-3.827,3.079,,0.172,,b,0.75,-0.27,1.134,,49.24,HOO,-1.72067,0.100394,0.00232366,0.849642 kka2_1:8_G233V,kka2_1:8_233,Kka2,kka2_1:8,P00552,0.849642,NO,233,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.748,-3.827,3.079,,0.172,,b,0.75,-0.27,1.134,,49.24,HOO,-1.72067,0.100394,0.00232366,0.849642 beta-lactamase_2500_V72I,beta-lactamase_2500_72,TEM-1,beta-lactamase_2500,P62593,0.849697,NO,72,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.658,-3.311,1.653,,,H,A,0.44,-1.03,2.079,,65.73,BHH,-1.32167,0.361275,0.00501194,0.849697 kka2_1:4_P132L,kka2_1:4_132,Kka2,kka2_1:4,P00552,0.849702,NO,132,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.775,-3.61,2.835,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.168804,0.0018489,0.849702 gb1_Q258I,gb1_258,gb1,gb1,P06654,0.849718,NO,258,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.095,-3.812,1.717,,,,,,,0.86,,37.28,BPH,-1.88333,0.177985,0.00437595,0.849718 beta-lactamase_2500_I206G,beta-lactamase_2500_206,TEM-1,beta-lactamase_2500,P62593,0.84974,NO,206,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-2.429,-2.667,0.238,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.361275,0.00528934,0.84974 beta-lactamase_0_M115N,beta-lactamase_0_115,TEM-1,beta-lactamase_0,P62593,0.849756,NO,115,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.389,-4.013,2.624,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.0500837,0.0034337,0.849756 kka2_1:4_A87P,kka2_1:4_87,Kka2,kka2_1:4,P00552,0.84976,NO,87,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.917,-2.939,1.022,,1.039,S,L,0.46,1.57,22.675,22.675,65.53,AHO,-1.822,0.168804,0.00791281,0.84976 PSD95pdz3_L379H,PSD95pdz3_379,PSD95pdz3,PSD95pdz3,P31016,0.849786,NO,379,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.347,-4.587,3.24,5.37777,,,,,16.8762,,,,HHB,-1.35667,0.0758425,0.00029733,0.849786 beta-lactamase_0_L192T,beta-lactamase_0_192,TEM-1,beta-lactamase_0,P62593,0.849787,NO,192,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.254,-3.48,2.226,,0.095,H,A,0.55,0.35,1.756,,60.14,HHP,-1.41833,0.0500837,0.00558728,0.849787 beta-lactamase_G141Q,beta-lactamase_141,TEM-1,beta-lactamase,P62593,0.849845,NO,141,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.828,-3.982,3.154,5.03155,0.575,T,l,0.76,-0.28,0.198,,64.69,HOO,-1.08933,0.221079,0.0012419,0.849845 beta-lactamase_0_E175L,beta-lactamase_0_175,TEM-1,beta-lactamase_0,P62593,0.849851,NO,175,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.336,-3.444,1.108,,0.551,,A,1.04,1.05,2.334,,77.62,AAB,-1.31233,0.0500837,0.00482205,0.849851 beta-lactamase_0_N134G,beta-lactamase_0_134,TEM-1,beta-lactamase_0,P62593,0.849851,NO,134,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-0.879,-2.976,2.097,,0.138,H,A,0.61,-0.6,3.776,,53.15,HPH,-1.02233,0.0500837,0.000644786,0.849851 beta-lactamase_0_T138Y,beta-lactamase_0_138,TEM-1,beta-lactamase_0,P62593,0.849852,NO,138,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.506,-4.429,1.923,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.0500837,0.00487868,0.849852 beta-lactamase_156_T158M,beta-lactamase_156_158,TEM-1,beta-lactamase_156,P62593,0.849852,NO,158,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.116,-4.575,3.459,,0.036,,B,0.22,-0.85,3.771,,69.58,HPB,-1.269,0.111618,0.00341825,0.849852 beta-lactamase_156_A215W,beta-lactamase_156_215,TEM-1,beta-lactamase_156,P62593,0.849861,NO,215,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.503,-5.336,3.833,,,,a,0.46,-0.93,3.583,,74.48,HHO,-1.42633,0.111618,0.00544007,0.849861 beta-lactamase_156_Y262S,beta-lactamase_156_262,TEM-1,beta-lactamase_156,P62593,0.849865,NO,262,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.111618,0.00853516,0.849865 kka2_1:2_R147S,kka2_1:2_147,Kka2,kka2_1:2,P00552,0.849894,NO,147,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.123,-3.438,2.315,,0.094,H,A,1.2,0.97,0.425,,64.02,PBH,-1.98267,0.295029,0.00549168,0.849894 beta-lactamase_0_N152Q,beta-lactamase_0_152,TEM-1,beta-lactamase_0,P62593,0.849949,NO,152,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-2.757,-2.534,-0.223,,0.863,H,A,0.61,0.92,2.151,,77.62,BPH,-2.97,0.0500837,0.00471429,0.849949 kka2_1:8_R147I,kka2_1:8_147,Kka2,kka2_1:8,P00552,0.849954,NO,147,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.123,-4.139,3.016,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.100394,0.00549168,0.849954 kka2_1:8_R147I,kka2_1:8_147,Kka2,kka2_1:8,P00552,0.849954,NO,147,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.123,-4.139,3.016,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.100394,0.00549168,0.849954 beta-lactamase_0_E166N,beta-lactamase_0_166,TEM-1,beta-lactamase_0,P62593,0.84997,NO,166,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.756,-3.709,1.953,,0.508,G,A,1.04,1.05,17.227,17.227,73.08,OAH,-1.42233,0.0500837,0.00512989,0.84997 kka2_1:8_A222T,kka2_1:8_222,Kka2,kka2_1:8,P00552,0.850005,NO,222,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.725,-3.225,2.5,,,H,A,1.04,-1.21,,,,HHH,-1.10833,0.100394,0.00207657,0.850005 kka2_1:8_A222T,kka2_1:8_222,Kka2,kka2_1:8,P00552,0.850005,NO,222,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.725,-3.225,2.5,,,H,A,1.04,-1.21,,,,HHH,-1.10833,0.100394,0.00207657,0.850005 kka2_1:8_H188Q,kka2_1:8_188,Kka2,kka2_1:8,P00552,0.850031,NO,188,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-0.913,-2.723,1.81,,0.006,,A,0.87,-1.02,1.241,,47.73,PBO,-0.927333,0.100394,0.00273139,0.850031 kka2_1:8_H188Q,kka2_1:8_188,Kka2,kka2_1:8,P00552,0.850031,NO,188,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-0.913,-2.723,1.81,,0.006,,A,0.87,-1.02,1.241,,47.73,PBO,-0.927333,0.100394,0.00273139,0.850031 beta-lactamase_A15P,beta-lactamase_15,TEM-1,beta-lactamase,P62593,0.850062,NO,15,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.654,-3.789,2.135,,,,,,,31.998,31.998,93.01,HHH,-2.10833,0.221079,0.00248966,0.850062 beta-lactamase_0_T69N,beta-lactamase_0_69,TEM-1,beta-lactamase_0,P62593,0.85007,NO,69,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-0.973,-3.537,2.564,,,G,A,0.22,-1.24,0.505,,93.01,PPH,-1.01833,0.0500837,0.00127498,0.85007 beta-lactamase_0_E46K,beta-lactamase_0_46,TEM-1,beta-lactamase_0,P62593,0.85009,NO,46,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.94,-3.66,1.72,,0.021,E,B,1.04,0.14,30.306,30.306,59.44,HAH,-2.079,0.0500837,0.00427568,0.85009 kka2_1:4_L243V,kka2_1:4_243,Kka2,kka2_1:4,P00552,0.850148,NO,243,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-2.651,-2.869,0.218,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.168804,0.00884927,0.850148 kka2_1:2_T225L,kka2_1:2_225,Kka2,kka2_1:2,P00552,0.85018,NO,225,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.393,-2.612,0.219,,0.036,H,A,0.22,-1.22,4.554,,63.64,HPB,-1.58733,0.295029,0.0113598,0.85018 Pab1_Y143G,Pab1_143,Pab1,Pab1,P04147,0.850183,NO,143,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-1.961,-3.384,1.423,,0.409,H,A,,0.3,,,,HHA,-1.39633,0.175299,0.00160364,0.850183 beta-lactamase_P143V,beta-lactamase_143,TEM-1,beta-lactamase,P62593,0.850185,NO,143,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.967,-3.311,2.344,5.16366,0.075,H,A,0.99,-0.37,0.479,,66.78,OOB,-1.354,0.221079,0.00114551,0.850185 kka2_1:4_P194G,kka2_1:4_194,Kka2,kka2_1:4,P00552,0.85021,NO,194,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.846,-3.359,2.513,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.168804,0.00314194,0.85021 kka2_1:4_I29A,kka2_1:4_29,Kka2,kka2_1:4,P00552,0.850214,NO,29,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.692,-3.281,1.589,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.168804,0.00619521,0.850214 beta-lactamase_0_R59A,beta-lactamase_0_59,TEM-1,beta-lactamase_0,P62593,0.850224,NO,59,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.345,-3.163,1.818,,0.329,S,L,1.2,-0.09,2.919,,73.08,HBO,-2.24267,0.0500837,0.00318082,0.850224 kka2_1:1_L60I,kka2_1:1_60,Kka2,kka2_1:1,P00552,0.8503,NO,60,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.997,-2.513,1.516,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.520039,0.00262176,0.8503 beta-lactamase_I3W,beta-lactamase_3,TEM-1,beta-lactamase,P62593,0.850317,NO,3,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-2.143,-5.085,2.942,,,,,,,3.946,,93.01,PHP,-2.21633,0.221079,0.00349304,0.850317 beta-lactamase_M184A,beta-lactamase_184,TEM-1,beta-lactamase,P62593,0.850317,NO,184,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.593,-2.223,0.63,5.39575,,H,A,1.3,-0.87,2.893,,62.94,HHH,-1.41,0.221079,0.00356019,0.850317 beta-lactamase_R63C,beta-lactamase_63,TEM-1,beta-lactamase,P62593,0.850317,NO,63,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-0.943,-5.05,4.107,5.49979,0.218,,B,0.45,-0.31,0.677,,44.06,ABH,-0.992333,0.221079,0.00126938,0.850317 kka2_1:8_S204I,kka2_1:8_204,Kka2,kka2_1:8,P00552,0.850317,NO,204,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.353,-3.845,2.492,,0.144,E,A,0.27,-1.2,0.368,,65.53,HPO,-0.953333,0.100394,0.00881794,0.850317 kka2_1:8_S204I,kka2_1:8_204,Kka2,kka2_1:8,P00552,0.850317,NO,204,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.353,-3.845,2.492,,0.144,E,A,0.27,-1.2,0.368,,65.53,HPO,-0.953333,0.100394,0.00881794,0.850317 beta-lactamase_V82F,beta-lactamase_82,TEM-1,beta-lactamase,P62593,0.850369,NO,82,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.325,-3.991,2.666,5.27777,0.267,H,A,0.96,0.08,1.379,,93.01,BHA,-1.28567,0.221079,0.00397046,0.850369 beta-lactamase_0_V259P,beta-lactamase_0_259,TEM-1,beta-lactamase_0,P62593,0.850377,NO,259,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.0500837,0.0070773,0.850377 beta-lactamase_0_R41M,beta-lactamase_0_41,TEM-1,beta-lactamase_0,P62593,0.850385,NO,41,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-0.942,-4.506,3.564,,0.321,E,B,1.2,-0.07,2.68,,65.03,HBH,-1.30267,0.0500837,0.00123327,0.850385 beta-lactamase_S2G,beta-lactamase_2,TEM-1,beta-lactamase,P62593,0.850417,NO,2,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.942,-3.184,1.242,,,,,,,2.36,,65.38,HPH,-2.02767,0.221079,0.00227352,0.850417 beta-lactamase_0_L47H,beta-lactamase_0_47,TEM-1,beta-lactamase_0,P62593,0.850418,NO,47,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.876,-2.811,0.935,,0.007,E,B,0.55,0.2,1.024,,67.83,AHA,-1.639,0.0500837,0.00439844,0.850418 beta-lactamase_V106T,beta-lactamase_106,TEM-1,beta-lactamase,P62593,0.850432,NO,106,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.218,-3.428,2.21,5.23115,0.258,T,A,0.96,0.24,1.188,,72.73,OHP,-1.04933,0.221079,0.00304168,0.850432 kka2_1:4_P12Q,kka2_1:4_12,Kka2,kka2_1:4,P00552,0.85048,NO,12,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.853,-3.937,3.084,,,,B,0.52,1.25,0.843,,48.11,POH,-1.80767,0.168804,0.00500011,0.85048 beta-lactamase_R41W,beta-lactamase_41,TEM-1,beta-lactamase,P62593,0.850484,NO,41,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-0.942,-5.348,4.406,5.69185,0.321,E,B,0.91,-0.07,4.357,,65.03,HBH,-1.30267,0.221079,0.00123327,0.850484 beta-lactamase_T116A,beta-lactamase_116,TEM-1,beta-lactamase,P62593,0.850484,NO,116,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.28,-2.469,1.189,4.78335,0.115,E,B,0.69,-0.12,0.343,,67.48,HPH,-1.39967,0.221079,0.00336175,0.850484 beta-lactamase_H5G,beta-lactamase_5,TEM-1,beta-lactamase,P62593,0.850514,NO,5,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-2.698,-3.537,0.839,,,,,,,1.865,,72.73,PBH,-2.36967,0.221079,0.00292712,0.850514 kka2_1:1_R177D,kka2_1:1_177,Kka2,kka2_1:1,P00552,0.850525,NO,177,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.282,-3.754,1.472,,0.521,T,A,1.2,0.16,1.842,,63.64,HBH,-2.36967,0.520039,0.00768224,0.850525 gb1_A246W,gb1_246,gb1,gb1,P06654,0.850534,NO,246,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.175,-5.058,3.883,,,,,,,,,,AHH,-1.87033,0.177985,0.00190625,0.850534 beta-lactamase_T126N,beta-lactamase_126,TEM-1,beta-lactamase,P62593,0.85054,NO,126,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.122,-3.467,2.345,4.82694,0.05,H,A,0.3,-0.05,1.14,,44.41,HPH,-1.60467,0.221079,0.00244552,0.85054 beta-lactamase_N168Q,beta-lactamase_168,TEM-1,beta-lactamase,P62593,0.850551,NO,168,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-1.029,-3.749,2.72,5.42128,0.113,G,A,0.09,-0.4,1.211,,44.41,HPA,-1.13233,0.221079,0.00288667,0.850551 E1_Ubiquitin_G47E,E1_Ubiquitin_47,Uba1,E1_Ubiquitin,P0CG63,0.850575,NO,47,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.999,-3.231,2.232,,0.057,T,l,,-1.21,,,,HOB,-1.195,0.18783,0.00142261,0.850575 beta-lactamase_0_G43T,beta-lactamase_0_43,TEM-1,beta-lactamase_0,P62593,0.850609,NO,43,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.62,-3.646,3.026,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.0500837,0.00120151,0.850609 Pab1_I137C,Pab1_137,Pab1,Pab1,P04147,0.850613,NO,137,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.212,-4.454,3.242,,0.068,,B,0.77,0.35,,,,AHA,-1.314,0.175299,0.000342224,0.850613 beta-lactamase_G263Q,beta-lactamase_263,TEM-1,beta-lactamase,P62593,0.850621,NO,263,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-2.031,-2.583,0.552,5.09799,0.517,S,l,0.77,0.31,16.425,16.425,77.62,POP,-1.78267,0.221079,0.0110582,0.850621 kka2_1:2_T28D,kka2_1:2_28,Kka2,kka2_1:2,P00552,0.850632,NO,28,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.883,-2.685,0.802,,0.353,S,B,0.22,2.02,2.655,,63.64,PPH,-1.74467,0.295029,0.00743084,0.850632 kka2_1:4_T225Q,kka2_1:4_225,Kka2,kka2_1:4,P00552,0.850725,NO,225,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.393,-3.262,0.869,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.168804,0.0113598,0.850725 beta-lactamase_0_R176T,beta-lactamase_0_176,TEM-1,beta-lactamase_0,P62593,0.850769,NO,176,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-0.863,-3.421,2.558,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.0500837,0.00105554,0.850769 kka2_1:8_R145T,kka2_1:8_145,Kka2,kka2_1:8,P00552,0.850809,NO,145,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.804,-3.648,1.844,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.100394,0.00846663,0.850809 kka2_1:8_R145T,kka2_1:8_145,Kka2,kka2_1:8,P00552,0.850809,NO,145,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.804,-3.648,1.844,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.100394,0.00846663,0.850809 kka2_1:4_R147F,kka2_1:4_147,Kka2,kka2_1:4,P00552,0.850849,NO,147,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.123,-4.324,3.201,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.168804,0.00549168,0.850849 kka2_1:2_S204K,kka2_1:2_204,Kka2,kka2_1:2,P00552,0.850859,NO,204,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.353,-3.511,2.158,,0.144,E,A,0.27,-1.2,2.442,,65.53,HPO,-0.953333,0.295029,0.00881794,0.850859 beta-lactamase_R91A,beta-lactamase_91,TEM-1,beta-lactamase,P62593,0.850941,NO,91,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.392,-2.55,1.158,5.92536,0.444,,B,0.68,0.96,1.318,,50.35,OBB,-1.73367,0.221079,0.00380226,0.850941 kka2_1:2_A78R,kka2_1:2_78,Kka2,kka2_1:2,P00552,0.850979,NO,78,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.744,-3.937,2.193,,0.078,.,B,0.46,-0.53,0.206,,56.06,OHH,-1.863,0.295029,0.00457299,0.850979 beta-lactamase_0_T112Y,beta-lactamase_0_112,TEM-1,beta-lactamase_0,P62593,0.851074,NO,112,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.186,-4.422,2.236,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.0500837,0.00531334,0.851074 kka2_1:2_E161R,kka2_1:2_161,Kka2,kka2_1:2,P00552,0.851085,NO,161,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.581,-3.888,2.307,,0.829,G,A,1.52,2.24,1.612,,92.05,AAB,-1.861,0.295029,0.00760103,0.851085 beta-lactamase_L191Y,beta-lactamase_191,TEM-1,beta-lactamase,P62593,0.851108,NO,191,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.087,-3.913,2.826,5.72226,,H,A,1.07,0.09,1.23,,63.29,BHH,-1.445,0.221079,0.00263549,0.851108 beta-lactamase_G226M,beta-lactamase_226,TEM-1,beta-lactamase,P62593,0.851158,NO,226,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.461,-4.924,3.463,5.70682,0.701,T,l,0.77,-0.25,3.199,,74.48,HOH,-1.42933,0.221079,0.00665294,0.851158 beta-lactamase_F13G,beta-lactamase_13,TEM-1,beta-lactamase,P62593,0.851163,NO,13,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-2.394,-3.498,1.104,,,,,,,4.079,,77.62,OHH,-2.382,0.221079,0.0029078,0.851163 PSD95pdz3_F337T,PSD95pdz3_337,PSD95pdz3,PSD95pdz3,P31016,0.851188,NO,337,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.524,-3.328,1.804,5.22838,,,,,13.4936,,,,HHH,-1.59467,0.0758425,0.000875287,0.851188 beta-lactamase_0_A215E,beta-lactamase_0_215,TEM-1,beta-lactamase_0,P62593,0.851194,NO,215,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.503,-3.531,2.028,,,,a,0.46,-0.93,0.494,,74.48,HHO,-1.42633,0.0500837,0.00544007,0.851194 beta-lactamase_0_I54L,beta-lactamase_0_54,TEM-1,beta-lactamase_0,P62593,0.851212,NO,54,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-2.838,-2.471,-0.367,,0.669,E,B,0.48,-0.14,0.541,,73.78,BHH,-2.337,0.0500837,0.00403589,0.851212 kka2_1:4_A110K,kka2_1:4_110,Kka2,kka2_1:4,P00552,0.851256,NO,110,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.064,-3.119,1.055,,0.175,H,A,0.46,-1.19,23.237,23.237,71.59,OHA,-1.91867,0.168804,0.00759851,0.851256 beta-lactamase_39_M67C,beta-lactamase_39_67,TEM-1,beta-lactamase_39,P62593,0.851306,NO,67,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-2.231,-2.364,0.133,,0.006,G,P,0.55,-0.81,1.463,,65.03,HHP,-1.502,0.0495842,0.00409753,0.851306 beta-lactamase_2500_A170P,beta-lactamase_2500_170,TEM-1,beta-lactamase_2500,P62593,0.851334,NO,170,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.237,-3.899,2.662,,0.126,,L,0.46,-0.35,2.427,,64.69,AHH,-1.63267,0.361275,0.00431903,0.851334 beta-lactamase_0_V31P,beta-lactamase_0_31,TEM-1,beta-lactamase_0,P62593,0.851336,NO,31,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.822,-4.128,2.306,,,H,A,0.44,-0.46,4.126,,73.78,BHB,-2.03767,0.0500837,0.00478065,0.851336 kka2_1:2_D159R,kka2_1:2_159,Kka2,kka2_1:2,P00552,0.851355,NO,159,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.82,-3.995,3.175,,0.28,.,B,0.75,1.25,0.899,,48.11,HAA,-1.48333,0.295029,0.0030485,0.851355 Pab1_G188Y,Pab1_188,Pab1,Pab1,P04147,0.851498,NO,188,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.809,-4.205,3.396,,0.379,E,g,,2.18,,,,POH,-1.14633,0.175299,0.000280911,0.851498 beta-lactamase_0_V260L,beta-lactamase_0_260,TEM-1,beta-lactamase_0,P62593,0.851508,NO,260,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.0500837,0.00471757,0.851508 beta-lactamase_0_A34I,beta-lactamase_0_34,TEM-1,beta-lactamase_0,P62593,0.851518,NO,34,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.059,-2.06,0.001,,,H,A,0.46,-0.54,3.998,,73.78,AHA,-1.74967,0.0500837,0.00407913,0.851518 beta-lactamase_2500_T147K,beta-lactamase_2500_147,TEM-1,beta-lactamase_2500,P62593,0.851544,NO,147,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.149,-3.536,2.387,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.361275,0.00226017,0.851544 beta-lactamase_0_T69P,beta-lactamase_0_69,TEM-1,beta-lactamase_0,P62593,0.851602,NO,69,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-0.973,-3.715,2.742,,,G,A,0.22,-1.24,0.505,,93.01,PPH,-1.01833,0.0500837,0.00127498,0.851602 kka2_1:2_D101S,kka2_1:2_101,Kka2,kka2_1:2,P00552,0.851628,NO,101,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.028,-3.266,2.238,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.295029,0.00423361,0.851628 beta-lactamase_0_A222N,beta-lactamase_0_222,TEM-1,beta-lactamase_0,P62593,0.851712,NO,222,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.103,-3.751,1.648,,0.233,H,A,0.46,-0.25,2.015,,77.62,PHH,-1.63733,0.0500837,0.00466094,0.851712 kka2_1:4_W91H,kka2_1:4_91,Kka2,kka2_1:4,P00552,0.851766,NO,91,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-1.178,-4.573,3.395,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.168804,0.00358653,0.851766 beta-lactamase_2500_T116Q,beta-lactamase_2500_116,TEM-1,beta-lactamase_2500,P62593,0.851815,NO,116,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.28,-3.898,2.618,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.361275,0.00336175,0.851815 beta-lactamase_V82R,beta-lactamase_82,TEM-1,beta-lactamase,P62593,0.851833,NO,82,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.325,-4.101,2.776,5.27777,0.267,H,A,0.96,0.08,1.379,,93.01,BHA,-1.28567,0.221079,0.00397046,0.851833 kka2_1:4_Q136F,kka2_1:4_136,Kka2,kka2_1:4,P00552,0.851855,NO,136,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-3.021,-4.399,1.378,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.168804,0.00624149,0.851855 beta-lactamase_156_E87R,beta-lactamase_156_87,TEM-1,beta-lactamase_156,P62593,0.851857,NO,87,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.421,-3.739,2.318,,0.048,,B,1.04,0.92,1.754,,64.69,PAP,-1.969,0.111618,0.00337888,0.851857 beta-lactamase_T178C,beta-lactamase_178,TEM-1,beta-lactamase,P62593,0.851871,NO,178,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-0.791,-4.637,3.846,5.06452,0.029,E,B,0.3,-1.07,,,,APP,-0.947667,0.221079,0.000684366,0.851871 beta-lactamase_156_S104M,beta-lactamase_156_104,TEM-1,beta-lactamase_156,P62593,0.851912,NO,104,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.015,-4.54,3.525,,0.04,,b,0.27,0.57,4.02,,63.29,HPO,-1.05267,0.111618,0.00218083,0.851912 beta-lactamase_G141D,beta-lactamase_141,TEM-1,beta-lactamase,P62593,0.852017,NO,141,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.828,-2.284,1.456,5.03155,0.575,T,l,0.76,-0.28,0.198,,64.69,HOO,-1.08933,0.221079,0.0012419,0.852017 beta-lactamase_L100T,beta-lactamase_100,TEM-1,beta-lactamase,P62593,0.852017,NO,100,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.218,-3.502,2.284,5.60291,0.343,,B,1.3,0.13,1.173,,63.29,AHH,-1.23467,0.221079,0.00413885,0.852017 beta-lactamase_L247C,beta-lactamase_247,TEM-1,beta-lactamase,P62593,0.852017,NO,247,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.48,-4.754,3.274,5.28771,0.007,E,B,2.89,-0.72,2.951,,63.99,HHO,-1.79833,0.221079,0.00611275,0.852017 beta-lactamase_T262L,beta-lactamase_262,TEM-1,beta-lactamase,P62593,0.852017,NO,262,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.332,-3.331,1.999,5.06002,0.108,E,B,0.3,-0.55,1.423,,67.83,PPO,-2.081,0.221079,0.00853516,0.852017 kka2_1:2_A150T,kka2_1:2_150,Kka2,kka2_1:2,P00552,0.852051,NO,150,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.949,-3.378,2.429,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.295029,0.0045009,0.852051 beta-lactamase_0_C75E,beta-lactamase_0_75,TEM-1,beta-lactamase_0,P62593,0.852053,NO,75,C,E,CE,Special,negativeCharge,5.07,3.22,-1.85,170,121,147,26,108.5,138.4,29.9,-1.245,-3.874,2.629,,,H,A,0.46,-0.87,2.256,,50,HOO,-1.24333,0.0500837,0.0034616,0.852053 hsp90_N588A,hsp90_588,hsp90,hsp90,P02829,0.852087,NO,588,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-3.051,-2.456,0,4.61142,0.019,H,A,0.14,0.39,,,,HPH,-3.12167,0.368192,0.000222939,0.852087 beta-lactamase_2500_T264C,beta-lactamase_2500_264,TEM-1,beta-lactamase_2500,P62593,0.852089,NO,264,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.361275,0.0119399,0.852089 kka2_1:4_R202F,kka2_1:4_202,Kka2,kka2_1:4,P00552,0.852138,NO,202,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.761,-4.435,2.674,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.168804,0.00696498,0.852138 beta-lactamase_0_G142R,beta-lactamase_0_142,TEM-1,beta-lactamase_0,P62593,0.852142,NO,142,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.707,-3.93,3.223,,0.034,,p,0.29,-0.64,1.947,,64.69,OOO,-0.834,0.0500837,0.00060149,0.852142 gb1_K236P,gb1_236,gb1,gb1,P06654,0.852156,NO,236,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-2.119,-3.613,1.494,,,,,,,1.083,,45.54,OBP,-1.758,0.177985,0.00255408,0.852156 beta-lactamase_N168T,beta-lactamase_168,TEM-1,beta-lactamase,P62593,0.852165,NO,168,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-1.029,-2.214,1.185,5.42128,0.113,G,A,0.09,-0.4,1.211,,44.41,HPA,-1.13233,0.221079,0.00288667,0.852165 kka2_1:8_M116T,kka2_1:8_116,Kka2,kka2_1:8,P00552,0.852177,NO,116,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-2.482,-2.959,0.477,,,H,A,1.59,-0.88,4.659,,71.59,HHH,-1.63867,0.100394,0.00745147,0.852177 kka2_1:8_M116T,kka2_1:8_116,Kka2,kka2_1:8,P00552,0.852177,NO,116,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-2.482,-2.959,0.477,,,H,A,1.59,-0.88,4.659,,71.59,HHH,-1.63867,0.100394,0.00745147,0.852177 beta-lactamase_0_G52W,beta-lactamase_0_52,TEM-1,beta-lactamase_0,P62593,0.852193,NO,52,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.149,-5.364,4.215,,0.299,,l,0.29,-0.04,1.164,,64.69,POB,-1.66267,0.0500837,0.00340138,0.852193 beta-lactamase_2500_A170I,beta-lactamase_2500_170,TEM-1,beta-lactamase_2500,P62593,0.852229,NO,170,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.237,-3.643,2.406,,0.126,,L,0.46,-0.35,2.427,,64.69,AHH,-1.63267,0.361275,0.00431903,0.852229 kka2_1:2_G55M,kka2_1:2_55,Kka2,kka2_1:2,P00552,0.852254,NO,55,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.625,-3.536,1.911,,0.517,S,b,0.75,1.19,15.753,15.753,63.64,POH,-2.05967,0.295029,0.00667877,0.852254 beta-lactamase_2500_T187A,beta-lactamase_2500_187,TEM-1,beta-lactamase_2500,P62593,0.852274,NO,187,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.401,-3.072,1.671,,0.007,H,A,0.22,-1.19,3.91,,67.48,PPH,-1.69633,0.361275,0.00491782,0.852274 kka2_1:8_A108W,kka2_1:8_108,Kka2,kka2_1:8,P00552,0.852287,NO,108,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.061,-5.601,3.54,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.100394,0.00751209,0.852287 kka2_1:8_A108W,kka2_1:8_108,Kka2,kka2_1:8,P00552,0.852287,NO,108,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.061,-5.601,3.54,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.100394,0.00751209,0.852287 kka2_1:8_A137Y,kka2_1:8_137,Kka2,kka2_1:8,P00552,0.852306,NO,137,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.156,-4.084,1.928,,0.029,H,A,1.04,0.34,2.886,,63.26,PHB,-2.559,0.100394,0.00515054,0.852306 kka2_1:8_A137Y,kka2_1:8_137,Kka2,kka2_1:8,P00552,0.852306,NO,137,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.156,-4.084,1.928,,0.029,H,A,1.04,0.34,2.886,,63.26,PHB,-2.559,0.100394,0.00515054,0.852306 beta-lactamase_2500_V101R,beta-lactamase_2500_101,TEM-1,beta-lactamase_2500,P62593,0.852331,NO,101,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.295,-4.134,2.839,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.361275,0.00374492,0.852331 beta-lactamase_39_D155T,beta-lactamase_39_155,TEM-1,beta-lactamase_39,P62593,0.852341,NO,155,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.889,-3.445,2.556,,0.049,,B,0.75,-0.9,3.208,,64.69,OAB,-1.62267,0.0495842,0.00135315,0.852341 beta-lactamase_I283W,beta-lactamase_283,TEM-1,beta-lactamase,P62593,0.852442,NO,283,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.638,-5.243,3.605,5.4178,0.165,H,A,1.23,0.04,1.576,,69.23,HHB,-1.735,0.221079,0.0429138,0.852442 beta-lactamase_E108P,beta-lactamase_108,TEM-1,beta-lactamase,P62593,0.852467,NO,108,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.46,-3.855,2.395,5.52079,0.572,G,A,0.52,1.87,1.973,,72.73,PAB,-1.437,0.221079,0.00413372,0.852467 beta-lactamase_0_D36N,beta-lactamase_0_36,TEM-1,beta-lactamase_0,P62593,0.852507,NO,36,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.732,-3.002,0.27,,0.555,H,A,0.75,1.17,13.689,13.689,77.62,AAP,-1.91167,0.0500837,0.00476483,0.852507 gb1_A246L,gb1_246,gb1,gb1,P06654,0.852559,NO,246,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.175,-2.869,1.694,,,,,,,,,,AHH,-1.87033,0.177985,0.00190625,0.852559 gb1_T237C,gb1_237,gb1,gb1,P06654,0.852559,NO,237,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.736,-4.709,2.973,,,,,,,0.218,,11.83,BPH,-2.27833,0.177985,0.00275316,0.852559 beta-lactamase_R162K,beta-lactamase_162,TEM-1,beta-lactamase,P62593,0.85256,NO,162,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.016,-2.948,1.932,5.34456,0.124,S,B,0.68,-0.37,31.656,31.656,64.69,ABH,-1.25,0.221079,0.000561334,0.85256 PSD95pdz3_A343R,PSD95pdz3_343,PSD95pdz3,PSD95pdz3,P31016,0.852584,NO,343,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.307,-3.39,2.083,5.585,,,,,14.728,,,,HHO,-1.22067,0.0758425,0.000798084,0.852584 PSD95pdz3_R312F,PSD95pdz3_312,PSD95pdz3,PSD95pdz3,P31016,0.852628,NO,312,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.582,-3.974,2.392,5.76826,,,,,12.2409,,,,OBB,-1.46667,0.0758425,0.00196255,0.852628 beta-lactamase_F149S,beta-lactamase_149,TEM-1,beta-lactamase,P62593,0.852674,NO,149,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.299,-2.783,1.484,5.54789,0.195,H,A,1.1,0.11,1.863,,63.99,HHH,-1.46067,0.221079,0.00418462,0.852674 kka2_1:1_V84A,kka2_1:1_84,Kka2,kka2_1:1,P00552,0.852674,NO,84,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-2.279,-1.994,-0.285,,0.258,E,B,0.44,1.03,3.484,,71.59,HHP,-2.337,0.520039,0.00724019,0.852674 beta-lactamase_625_G265Y,beta-lactamase_625_265,TEM-1,beta-lactamase_625,P62593,0.852683,NO,265,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.213352,0.00811926,0.852683 kka2_1:2_P76R,kka2_1:2_76,Kka2,kka2_1:2,P00552,0.8527,NO,76,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.449,-4.026,2.577,,0.331,.,B,0.52,-0.41,0.345,,63.64,HOO,-1.662,0.295029,0.00625685,0.8527 kka2_1:4_R140A,kka2_1:4_140,Kka2,kka2_1:4,P00552,0.852735,NO,140,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.351,-2.609,1.258,,0.12,H,A,1.2,0.2,2.561,,53.03,BBH,-1.885,0.168804,0.00430167,0.852735 beta-lactamase_0_Y44S,beta-lactamase_0_44,TEM-1,beta-lactamase_0,P62593,0.852737,NO,44,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-2.547,-3.605,1.058,,,E,B,0.21,-0.45,1.751,,73.78,OHH,-1.86267,0.0500837,0.00426364,0.852737 kka2_1:4_L39M,kka2_1:4_39,Kka2,kka2_1:4,P00552,0.852746,NO,39,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.223,-4.14,2.917,,,E,B,0.55,-1.21,1.998,,71.59,BHP,-1.69167,0.168804,0.00493618,0.852746 beta-lactamase_156_A34N,beta-lactamase_156_34,TEM-1,beta-lactamase_156,P62593,0.852763,NO,34,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.059,-3.965,1.906,,,H,A,0.46,-0.54,3.614,,73.78,AHA,-1.74967,0.111618,0.00407913,0.852763 beta-lactamase_625_P165F,beta-lactamase_625_165,TEM-1,beta-lactamase_625,P62593,0.85283,NO,165,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.373,-4.322,2.949,,0.203,T,A,0.52,-0.31,0.414,,73.78,AOA,-1.359,0.213352,0.00549538,0.85283 beta-lactamase_Y44V,beta-lactamase_44,TEM-1,beta-lactamase,P62593,0.852836,NO,44,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-2.547,-1.805,-0.742,5.6273,,E,B,2.55,-0.45,2.683,,73.78,OHH,-1.86267,0.221079,0.00426364,0.852836 beta-lactamase_I244T,beta-lactamase_244,TEM-1,beta-lactamase,P62593,0.852849,NO,244,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.555,-2.572,1.017,5.35885,,E,B,0.01,-0.84,0.379,,77.62,HHH,-1.385,0.221079,0.00605379,0.852849 beta-lactamase_G216V,beta-lactamase_216,TEM-1,beta-lactamase,P62593,0.852906,NO,216,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.477,-3.793,2.316,4.91694,0.437,I,A,0.23,-0.58,1.718,,74.48,HOO,-1.68067,0.221079,0.00639568,0.852906 gb1_A246E,gb1_246,gb1,gb1,P06654,0.85296,NO,246,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.175,-3.175,2,,,,,,,,,,AHH,-1.87033,0.177985,0.00190625,0.85296 kka2_1:2_I207V,kka2_1:2_207,Kka2,kka2_1:2,P00552,0.852966,NO,207,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.175,-1.613,0.438,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.295029,0.00611824,0.852966 kka2_1:8_Q136Y,kka2_1:8_136,Kka2,kka2_1:8,P00552,0.853001,NO,136,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-3.021,-4.291,1.27,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.100394,0.00624149,0.853001 kka2_1:8_Q136Y,kka2_1:8_136,Kka2,kka2_1:8,P00552,0.853001,NO,136,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-3.021,-4.291,1.27,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.100394,0.00624149,0.853001 beta-lactamase_2500_A183C,beta-lactamase_2500_183,TEM-1,beta-lactamase_2500,P62593,0.853007,NO,183,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.231,-4.684,3.453,,0.155,H,A,0.46,-0.91,12.189,,77.62,HHH,-1.53367,0.361275,0.00296631,0.853007 beta-lactamase_P105I,beta-lactamase_105,TEM-1,beta-lactamase,P62593,0.853028,NO,105,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.813,-4.008,3.195,5.08236,0.226,T,A,0.98,0.8,1.154,,63.29,POH,-1.01533,0.221079,0.0011981,0.853028 beta-lactamase_0_L28M,beta-lactamase_0_28,TEM-1,beta-lactamase_0,P62593,0.853048,NO,28,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.579,-4.156,2.577,,0.277,H,A,0.55,-0.16,9.35,9.35,93.01,PHH,-2.11333,0.0500837,0.00359321,0.853048 beta-lactamase_625_L197N,beta-lactamase_625_197,TEM-1,beta-lactamase_625,P62593,0.853055,NO,197,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.853,-4.12,3.267,,0.007,S,B,0.55,0.33,1.756,,60.14,HHP,-1.833,0.213352,0.00144602,0.853055 kka2_1:1_D118E,kka2_1:1_118,Kka2,kka2_1:1,P00552,0.853097,NO,118,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.07,-2.401,0.331,,0.61,H,A,0.75,-0.05,13.434,13.434,64.39,HAH,-1.32367,0.520039,0.0067852,0.853097 Pab1_L142T,Pab1_142,Pab1,Pab1,P04147,0.853132,NO,142,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.039,-3.239,2.2,,0.007,H,A,0.84,-0.65,,,,HHH,-1.487,0.175299,0.000335477,0.853132 kka2_1:1_S105G,kka2_1:1_105,Kka2,kka2_1:1,P00552,0.853141,NO,105,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.945,-2.84,0.895,,0.056,S,B,0.27,-1.04,3.442,,65.53,PPB,-2.17033,0.520039,0.00847233,0.853141 beta-lactamase_0_D207E,beta-lactamase_0_207,TEM-1,beta-lactamase_0,P62593,0.853143,NO,207,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.064,-2.615,0.551,,0.409,H,A,0.75,0.12,5.277,,77.62,HAH,-1.77033,0.0500837,0.00592942,0.853143 beta-lactamase_2500_M184Y,beta-lactamase_2500_184,TEM-1,beta-lactamase_2500,P62593,0.853145,NO,184,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.593,-4.027,2.434,,,H,A,0.55,-0.87,2.893,,62.94,HHH,-1.41,0.361275,0.00356019,0.853145 beta-lactamase_0_G43Q,beta-lactamase_0_43,TEM-1,beta-lactamase_0,P62593,0.853158,NO,43,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.62,-4.124,3.504,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.0500837,0.00120151,0.853158 beta-lactamase_0_G194F,beta-lactamase_0_194,TEM-1,beta-lactamase_0,P62593,0.853175,NO,194,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.396,-4.382,2.986,,0.276,S,b,0.29,0.36,3.017,,67.83,POA,-1.832,0.0500837,0.00392163,0.853175 beta-lactamase_0_V259E,beta-lactamase_0_259,TEM-1,beta-lactamase_0,P62593,0.853205,NO,259,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.0500837,0.0070773,0.853205 beta-lactamase_0_D113V,beta-lactamase_0_113,TEM-1,beta-lactamase_0,P62593,0.853254,NO,113,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.829,-3.01,1.181,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.0500837,0.00474112,0.853254 kka2_1:8_G245H,kka2_1:8_245,Kka2,kka2_1:8,P00552,0.853258,NO,245,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.812,-4.652,3.84,,0.655,T,g,0.75,0.03,1.148,,65.53,HOH,-1.19833,0.100394,0.00683899,0.853258 kka2_1:8_G245H,kka2_1:8_245,Kka2,kka2_1:8,P00552,0.853258,NO,245,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.812,-4.652,3.84,,0.655,T,g,0.75,0.03,1.148,,65.53,HOH,-1.19833,0.100394,0.00683899,0.853258 PSD95pdz3_P346Y,PSD95pdz3_346,PSD95pdz3,PSD95pdz3,P31016,0.853288,NO,346,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.236,-4.069,2.833,5.02406,,,,,14.6629,,,,OOH,-1.18367,0.0758425,0.000758563,0.853288 beta-lactamase_2500_S57W,beta-lactamase_2500_57,TEM-1,beta-lactamase_2500,P62593,0.853303,NO,57,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.918,-5.449,3.531,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.361275,0.00492804,0.853303 kka2_1:8_A34E,kka2_1:8_34,Kka2,kka2_1:8,P00552,0.853309,NO,34,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.928,-3.441,2.513,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.100394,0.00343484,0.853309 kka2_1:8_A34E,kka2_1:8_34,Kka2,kka2_1:8,P00552,0.853309,NO,34,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.928,-3.441,2.513,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.100394,0.00343484,0.853309 gb1_T237W,gb1_237,gb1,gb1,P06654,0.853361,NO,237,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.736,-5.047,3.311,,,,,,,0.218,,11.83,BPH,-2.27833,0.177985,0.00275316,0.853361 beta-lactamase_F64M,beta-lactamase_64,TEM-1,beta-lactamase,P62593,0.853381,NO,64,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-0.841,-4.255,3.414,5.70769,0.006,E,B,1.33,-0.95,,,,BHO,-0.892667,0.221079,0.000947691,0.853381 beta-lactamase_T126R,beta-lactamase_126,TEM-1,beta-lactamase,P62593,0.853388,NO,126,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.122,-3.84,2.718,4.82694,0.05,H,A,0.3,-0.05,1.14,,44.41,HPH,-1.60467,0.221079,0.00244552,0.853388 beta-lactamase_M115C,beta-lactamase_115,TEM-1,beta-lactamase,P62593,0.853401,NO,115,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.389,-4.767,3.378,4.89743,0.019,E,B,1.3,0.08,1.236,,69.58,OHP,-1.25433,0.221079,0.0034337,0.853401 beta-lactamase_0_H151N,beta-lactamase_0_151,TEM-1,beta-lactamase_0,P62593,0.853443,NO,151,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-2.96,-3.49,0.53,,0.594,H,A,0.17,0.1,9.375,,77.62,HBP,-2.34767,0.0500837,0.00216946,0.853443 beta-lactamase_N98C,beta-lactamase_98,TEM-1,beta-lactamase,P62593,0.853465,NO,98,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-2.973,-5.105,2.132,6.59973,0.963,G,A,1.07,1.35,1.332,,77.62,PPA,-2.07867,0.221079,0.00505389,0.853465 beta-lactamase_0_I45T,beta-lactamase_0_45,TEM-1,beta-lactamase_0,P62593,0.853486,NO,45,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-2.421,-2.537,0.116,,,E,B,0.48,-0.3,1.375,,77.62,HHA,-2.30267,0.0500837,0.00452842,0.853486 beta-lactamase_0_L79P,beta-lactamase_0_79,TEM-1,beta-lactamase_0,P62593,0.853491,NO,79,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.842,-4.102,3.26,,0.007,H,A,0.55,-0.16,5.053,,50.35,HHP,-1.44333,0.0500837,0.000947397,0.853491 beta-lactamase_0_D36A,beta-lactamase_0_36,TEM-1,beta-lactamase_0,P62593,0.853513,NO,36,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.732,-2.434,-0.298,,0.555,H,A,0.75,1.17,13.689,13.689,77.62,AAP,-1.91167,0.0500837,0.00476483,0.853513 beta-lactamase_R81E,beta-lactamase_81,TEM-1,beta-lactamase,P62593,0.853521,NO,81,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.466,-2.677,1.211,5.12166,0.218,H,A,0.68,1.66,1.236,,50,PBH,-1.60667,0.221079,0.00499763,0.853521 kka2_1:8_I196Q,kka2_1:8_196,Kka2,kka2_1:8,P00552,0.85354,NO,196,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-2.115,-4.384,2.269,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.100394,0.0107273,0.85354 kka2_1:8_I196Q,kka2_1:8_196,Kka2,kka2_1:8,P00552,0.85354,NO,196,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-2.115,-4.384,2.269,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.100394,0.0107273,0.85354 beta-lactamase_T198Y,beta-lactamase_198,TEM-1,beta-lactamase,P62593,0.85356,NO,198,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.168,-4.211,2.043,4.9209,0.489,,B,0.69,-0.13,0.37,,73.78,HPH,-1.98767,0.221079,0.004311,0.85356 kka2_1:2_L152T,kka2_1:2_152,Kka2,kka2_1:2,P00552,0.85356,NO,152,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.521,-2.936,1.415,,0.547,.,A,0.55,1.36,4.526,,63.64,OHH,-1.162,0.295029,0.00674868,0.85356 kka2_1:4_A34E,kka2_1:4_34,Kka2,kka2_1:4,P00552,0.853578,NO,34,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.928,-3.441,2.513,,0.417,.,B,0.46,2.29,0.262,,52.27,AHH,-1.747,0.168804,0.00343484,0.853578 kka2_1:4_L174M,kka2_1:4_174,Kka2,kka2_1:4,P00552,0.853597,NO,174,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.952,-2.955,2.003,,,H,A,0.55,-0.31,1.339,,51.89,BHB,-2.08533,0.168804,0.00438501,0.853597 kka2_1:2_I246K,kka2_1:2_246,Kka2,kka2_1:2,P00552,0.853601,NO,246,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-2.008,-3.871,1.863,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.295029,0.0139479,0.853601 beta-lactamase_0_G226Y,beta-lactamase_0_226,TEM-1,beta-lactamase_0,P62593,0.85361,NO,226,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.461,-4.462,3.001,,0.701,T,l,0.29,-0.25,23.034,23.034,74.48,HOH,-1.42933,0.0500837,0.00665294,0.85361 beta-lactamase_R271H,beta-lactamase_271,TEM-1,beta-lactamase,P62593,0.853646,NO,271,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.249,-4.461,3.212,5.24516,0.085,H,A,1.67,-0.05,0.474,,63.99,ABP,-1.36633,0.221079,0.00752082,0.853646 beta-lactamase_0_I45S,beta-lactamase_0_45,TEM-1,beta-lactamase_0,P62593,0.853656,NO,45,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-2.421,-2.717,0.296,,,E,B,0.48,-0.3,1.375,,77.62,HHA,-2.30267,0.0500837,0.00452842,0.853656 beta-lactamase_2500_P217G,beta-lactamase_2500_217,TEM-1,beta-lactamase_2500,P62593,0.853668,NO,217,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-2.062,-2.748,0.686,,0.496,I,A,0.52,-0.33,0.431,,74.48,OOH,-1.64333,0.361275,0.00463211,0.853668 beta-lactamase_V117T,beta-lactamase_117,TEM-1,beta-lactamase,P62593,0.853669,NO,117,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.53,-3.486,1.956,5.33594,,H,A,1.19,-0.34,1.182,,65.03,PHB,-1.741,0.221079,0.00467906,0.853669 beta-lactamase_0_R159A,beta-lactamase_0_159,TEM-1,beta-lactamase_0,P62593,0.853742,NO,159,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-0.94,-3.127,2.187,,0.316,,B,1.2,-0.55,1.426,,64.34,PBH,-1.011,0.0500837,0.00108472,0.853742 gb1_T237N,gb1_237,gb1,gb1,P06654,0.853761,NO,237,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.736,-2.055,0.319,,,,,,,0.218,,11.83,BPH,-2.27833,0.177985,0.00275316,0.853761 PSD95pdz3_D357L,PSD95pdz3_357,PSD95pdz3,PSD95pdz3,P31016,0.853774,NO,357,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.264,-3.49,2.226,5.22306,,,,,10.975,,,,OAP,-1.32367,0.0758425,0.000609015,0.853774 kka2_1:4_D159R,kka2_1:4_159,Kka2,kka2_1:4,P00552,0.853789,NO,159,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.82,-3.995,3.175,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.168804,0.0030485,0.853789 kka2_1:4_I115L,kka2_1:4_115,Kka2,kka2_1:4,P00552,0.853833,NO,115,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.606,-1.667,0.061,,0.105,H,A,1.52,-1.18,9.996,9.996,65.53,PHH,-2.205,0.168804,0.00836567,0.853833 beta-lactamase_0_V31M,beta-lactamase_0_31,TEM-1,beta-lactamase_0,P62593,0.853841,NO,31,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.822,-3.184,1.362,,,H,A,0.44,-0.46,4.126,,73.78,BHB,-2.03767,0.0500837,0.00478065,0.853841 beta-lactamase_0_V72R,beta-lactamase_0_72,TEM-1,beta-lactamase_0,P62593,0.853846,NO,72,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.658,-4.097,2.439,,,H,A,0.44,-1.03,2.964,,65.73,BHH,-1.32167,0.0500837,0.00501194,0.853846 beta-lactamase_0_T158V,beta-lactamase_0_158,TEM-1,beta-lactamase_0,P62593,0.85392,NO,158,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.116,-3.299,2.183,,0.036,,B,0.22,-0.85,1.041,,69.58,HPB,-1.269,0.0500837,0.00341825,0.85392 beta-lactamase_P224K,beta-lactamase_224,TEM-1,beta-lactamase,P62593,0.853929,NO,224,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.893,-3.389,2.496,5.179,0.383,,B,0.99,-0.3,0.383,,74.48,HOH,-1.26433,0.221079,0.00189564,0.853929 beta-lactamase_0_T263S,beta-lactamase_0_263,TEM-1,beta-lactamase_0,P62593,0.85393,NO,263,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.0500837,0.0110582,0.85393 beta-lactamase_D99W,beta-lactamase_99,TEM-1,beta-lactamase,P62593,0.854046,NO,99,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.191,-5.462,4.271,5.66081,0.402,G,A,0.23,0.36,1.318,,64.69,PAH,-1.794,0.221079,0.00305446,0.854046 beta-lactamase_A230M,beta-lactamase_230,TEM-1,beta-lactamase,P62593,0.854059,NO,230,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.154,-4.69,3.536,4.54336,0.01,E,B,0.75,-1.17,1.97,,50,HHA,-1.079,0.221079,0.00516841,0.854059 E1_Ubiquitin_Q40C,E1_Ubiquitin_40,Uba1,E1_Ubiquitin,P0CG63,0.854111,NO,40,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-1.48,-5.04,3.56,,0.387,G,A,,0.03,,,,OPP,-1.365,0.18783,0.0037961,0.854111 kka2_1:4_D62G,kka2_1:4_62,Kka2,kka2_1:4,P00552,0.854132,NO,62,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.591,-1.697,0.106,,0.262,H,A,0.29,0.08,14.756,14.756,64.39,PAA,-1.77833,0.168804,0.00744243,0.854132 kka2_1:8_A191W,kka2_1:8_191,Kka2,kka2_1:8,P00552,0.854156,NO,191,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.831,-5.414,4.583,,,,b,1.04,-0.94,1.306,,50,AHO,-0.868667,0.100394,0.00338807,0.854156 kka2_1:8_A191W,kka2_1:8_191,Kka2,kka2_1:8,P00552,0.854156,NO,191,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.831,-5.414,4.583,,,,b,1.04,-0.94,1.306,,50,AHO,-0.868667,0.100394,0.00338807,0.854156 beta-lactamase_39_M115D,beta-lactamase_39_115,TEM-1,beta-lactamase_39,P62593,0.854232,NO,115,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.389,-4.023,2.634,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.0495842,0.0034337,0.854232 beta-lactamase_T198P,beta-lactamase_198,TEM-1,beta-lactamase,P62593,0.854273,NO,198,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.168,-2.894,0.726,4.9209,0.489,,B,0.69,-0.13,0.37,,73.78,HPH,-1.98767,0.221079,0.004311,0.854273 beta-lactamase_0_S266L,beta-lactamase_0_266,TEM-1,beta-lactamase_0,P62593,0.854294,NO,266,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.0500837,0.0140785,0.854294 kka2_1:2_A150E,kka2_1:2_150,Kka2,kka2_1:2,P00552,0.854302,NO,150,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.949,-2.676,1.727,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.295029,0.0045009,0.854302 beta-lactamase_0_N98V,beta-lactamase_0_98,TEM-1,beta-lactamase_0,P62593,0.854304,NO,98,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-2.973,-3.696,0.723,,0.963,G,A,0.61,1.35,14.853,14.853,77.62,PPA,-2.07867,0.0500837,0.00505389,0.854304 beta-lactamase_156_Y95C,beta-lactamase_156_95,TEM-1,beta-lactamase_156,P62593,0.85434,NO,95,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-1.715,-4.95,3.235,,0.122,,b,0.21,-0.37,2.341,,77.62,BHP,-2.16167,0.111618,0.00479449,0.85434 beta-lactamase_625_A215P,beta-lactamase_625_215,TEM-1,beta-lactamase_625,P62593,0.854407,NO,215,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.503,-3.85,2.347,,,,a,0.46,-0.93,3.583,,74.48,HHO,-1.42633,0.213352,0.00544007,0.854407 beta-lactamase_2500_R41V,beta-lactamase_2500_41,TEM-1,beta-lactamase_2500,P62593,0.854429,NO,41,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-0.942,-3.751,2.809,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.361275,0.00123327,0.854429 beta-lactamase_S254P,beta-lactamase_254,TEM-1,beta-lactamase,P62593,0.854478,NO,254,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.126,-1.416,-0.71,5.49575,0.312,,a,0.25,-0.48,24.91,24.91,69.58,OPB,-2.215,0.221079,0.00369,0.854478 beta-lactamase_0_M184Y,beta-lactamase_0_184,TEM-1,beta-lactamase_0,P62593,0.854491,NO,184,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.593,-4.027,2.434,,,H,A,0.55,-0.87,13.292,13.292,62.94,HHH,-1.41,0.0500837,0.00356019,0.854491 beta-lactamase_0_N130D,beta-lactamase_0_130,TEM-1,beta-lactamase_0,P62593,0.854503,NO,130,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-0.798,-3.019,2.221,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.0500837,0.000683376,0.854503 Pab1_F173M,Pab1_173,Pab1,Pab1,P04147,0.854539,NO,173,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.477,-4.237,2.76,,,E,B,0.87,-0.16,1.636,,63.26,BHA,-1.36967,0.175299,0.00148779,0.854539 gb1_F256V,gb1_256,gb1,gb1,P06654,0.854557,NO,256,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.241,-3.081,1.84,,,,,,,,,,HHB,-2.04767,0.177985,0.00435993,0.854557 beta-lactamase_0_K53G,beta-lactamase_0_53,TEM-1,beta-lactamase_0,P62593,0.854563,NO,53,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-2.313,-2.824,0.511,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.0500837,0.00383383,0.854563 beta-lactamase_0_V260R,beta-lactamase_0_260,TEM-1,beta-lactamase_0,P62593,0.854581,NO,260,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.0500837,0.00471757,0.854581 beta-lactamase_0_D207H,beta-lactamase_0_207,TEM-1,beta-lactamase_0,P62593,0.854641,NO,207,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.064,-3.07,1.006,,0.409,H,A,0.75,0.12,5.277,,77.62,HAH,-1.77033,0.0500837,0.00592942,0.854641 beta-lactamase_L136M,beta-lactamase_136,TEM-1,beta-lactamase,P62593,0.854713,NO,136,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.232,-2.988,1.756,5.31114,,H,A,2.89,-0.34,1.539,,48.95,HHH,-1.088,0.221079,0.00442304,0.854713 beta-lactamase_M1I,beta-lactamase_1,TEM-1,beta-lactamase,P62593,0.854809,NO,1,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.998,-2.792,0.794,,,,,,,,,,OHP,-1.97,0.221079,0.00162771,0.854809 Ubiquitin_D32V,Ubiquitin_32,Uba1,Ubiquitin,P0CG48,0.854839,NO,32,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.451,-3.627,2.176,4.96502,0.835,H,A,,1.4,,,,PAB,-1.47067,0.205827,0.000758819,0.854839 Ubiquitin_D32Y,Ubiquitin_32,Uba1,Ubiquitin,P0CG48,0.854839,NO,32,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.451,-2.955,1.504,4.96502,0.835,H,A,,1.4,,,,PAB,-1.47067,0.205827,0.000758819,0.854839 Ubiquitin_D39R,Ubiquitin_39,Uba1,Ubiquitin,P0CG48,0.854839,NO,39,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.792,-2.999,1.207,5.1607,0.433,G,A,,0.55,,,,OAP,-1.754,0.205827,0.00071409,0.854839 Ubiquitin_H68N,Ubiquitin_68,Uba1,Ubiquitin,P0CG48,0.854839,NO,68,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-1.869,-2.928,1.059,4.81902,0.194,E,B,0.72,-1.02,21.325,21.325,65.11,HBH,-1.583,0.205827,0.000925438,0.854839 Ubiquitin_I13D,Ubiquitin_13,Uba1,Ubiquitin,P0CG48,0.854839,NO,13,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.554,-4.002,2.448,5.19411,0.038,E,B,,-0.2,,,,PHP,-1.48,0.205827,0.000716423,0.854839 Ubiquitin_I13E,Ubiquitin_13,Uba1,Ubiquitin,P0CG48,0.854839,NO,13,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.554,-3.845,2.291,5.19411,0.038,E,B,,-0.2,,,,PHP,-1.48,0.205827,0.000716423,0.854839 Ubiquitin_I30Y,Ubiquitin_30,Uba1,Ubiquitin,P0CG48,0.854839,NO,30,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.205,-3.986,2.781,4.80264,,H,A,,-0.51,,,,BHP,-1.45133,0.205827,0.000720128,0.854839 Ubiquitin_K11L,Ubiquitin_11,Uba1,Ubiquitin,P0CG48,0.854839,NO,11,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.354,-3.33,1.976,5.16813,0.401,,B,2.81,0.84,0.335,,25.84,OBP,-1.346,0.205827,0.000535553,0.854839 Ubiquitin_N60F,Ubiquitin_60,Uba1,Ubiquitin,P0CG48,0.854839,NO,60,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-1.775,-4.362,2.587,5.00332,0.775,T,L,,0.33,,,,HPH,-1.532,0.205827,0.000814061,0.854839 Ubiquitin_S65L,Ubiquitin_65,Uba1,Ubiquitin,P0CG48,0.854839,NO,65,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.535,-3.434,1.899,4.99442,0.168,,b,0.25,-0.68,16.756,16.756,33.87,APP,-1.626,0.205827,0.000546776,0.854839 Ubiquitin_T66Q,Ubiquitin_66,Uba1,Ubiquitin,P0CG48,0.854839,NO,66,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.58,-3.094,1.514,5.02702,0.46,E,B,0.8,-0.81,28.36,28.36,39.71,PPH,-1.51667,0.205827,0.000598414,0.854839 beta-lactamase_K30E,beta-lactamase_30,TEM-1,beta-lactamase,P62593,0.854878,NO,30,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-2.307,-2.686,0.379,5.30605,0.142,H,A,1.82,-0.65,2.434,,93.01,HBH,-2.32833,0.221079,0.00448593,0.854878 beta-lactamase_2500_I206H,beta-lactamase_2500_206,TEM-1,beta-lactamase_2500,P62593,0.854901,NO,206,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-2.429,-4.842,2.413,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.361275,0.00528934,0.854901 kka2_1:1_V113T,kka2_1:1_113,Kka2,kka2_1:1,P00552,0.854903,NO,113,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.233,-3.45,2.217,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.520039,0.00650191,0.854903 beta-lactamase_D113P,beta-lactamase_113,TEM-1,beta-lactamase,P62593,0.854928,NO,113,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.829,-3.062,1.233,6.04499,0.665,T,A,0.23,0.91,21.104,21.104,73.08,PAO,-1.703,0.221079,0.00474112,0.854928 gb1_A249D,gb1_249,gb1,gb1,P06654,0.854954,NO,249,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.739,-3.517,1.778,,,,,,,0.252,,44.87,AHH,-1.67367,0.177985,0.00333585,0.854954 Pab1_T145F,Pab1_145,Pab1,Pab1,P04147,0.854995,NO,145,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.067,-3.884,2.817,,0.237,H,A,0.3,0.69,,,,APH,-1.135,0.175299,0.000331088,0.854995 beta-lactamase_0_M66C,beta-lactamase_0_66,TEM-1,beta-lactamase_0,P62593,0.85502,NO,66,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.362,-4.734,3.372,,0.013,,A,0.55,-0.7,1.204,,73.08,OHH,-1.49567,0.0500837,0.00412876,0.85502 beta-lactamase_0_T139D,beta-lactamase_0_139,TEM-1,beta-lactamase_0,P62593,0.855034,NO,139,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.901,-3.596,1.695,,0.216,H,A,0.22,0.39,0.421,,77.62,PPH,-2.04667,0.0500837,0.00441837,0.855034 kka2_1:4_Q27A,kka2_1:4_27,Kka2,kka2_1:4,P00552,0.855037,NO,27,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-1.659,-3.31,1.651,,0.608,,A,0.4,0.71,1.498,,65.53,PPP,-1.90733,0.168804,0.00595365,0.855037 beta-lactamase_A170Q,beta-lactamase_170,TEM-1,beta-lactamase,P62593,0.855045,NO,170,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.237,-4.086,2.849,5.19261,0.126,,L,2.34,-0.35,2.427,,64.69,AHH,-1.63267,0.221079,0.00431903,0.855045 beta-lactamase_0_V82K,beta-lactamase_0_82,TEM-1,beta-lactamase_0,P62593,0.855063,NO,82,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.325,-3.754,2.429,,0.267,H,A,0.44,0.08,1.893,,93.01,BHA,-1.28567,0.0500837,0.00397046,0.855063 beta-lactamase_P224G,beta-lactamase_224,TEM-1,beta-lactamase,P62593,0.855071,NO,224,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.893,-3.351,2.458,5.179,0.383,,B,0.99,-0.3,0.383,,74.48,HOH,-1.26433,0.221079,0.00189564,0.855071 PSD95pdz3_P346F,PSD95pdz3_346,PSD95pdz3,PSD95pdz3,P31016,0.855077,NO,346,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.236,-4.199,2.963,5.02406,,,,,14.6629,,,,OOH,-1.18367,0.0758425,0.000758563,0.855077 kka2_1:4_R253T,kka2_1:4_253,Kka2,kka2_1:4,P00552,0.855079,NO,253,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.356,-3.535,2.179,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.168804,0.0144195,0.855079 beta-lactamase_0_T186H,beta-lactamase_0_186,TEM-1,beta-lactamase_0,P62593,0.855087,NO,186,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.522,-4.717,2.195,,0.396,H,A,0.22,-0.28,16.606,16.606,77.62,HPP,-1.77633,0.0500837,0.00485034,0.855087 beta-lactamase_L38C,beta-lactamase_38,TEM-1,beta-lactamase,P62593,0.855161,NO,38,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.343,-4.841,3.498,5.23728,0.088,H,A,1.75,0.2,1.986,,64.34,PHO,-1.78033,0.221079,0.00373244,0.855161 kka2_1:8_S204E,kka2_1:8_204,Kka2,kka2_1:8,P00552,0.855201,NO,204,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.353,-3.494,2.141,,0.144,E,A,0.27,-1.2,0.368,,65.53,HPO,-0.953333,0.100394,0.00881794,0.855201 kka2_1:8_S204E,kka2_1:8_204,Kka2,kka2_1:8,P00552,0.855201,NO,204,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.353,-3.494,2.141,,0.144,E,A,0.27,-1.2,0.368,,65.53,HPO,-0.953333,0.100394,0.00881794,0.855201 beta-lactamase_T116C,beta-lactamase_116,TEM-1,beta-lactamase,P62593,0.855275,NO,116,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.28,-4.831,3.551,4.78335,0.115,E,B,0.69,-0.12,0.343,,67.48,HPH,-1.39967,0.221079,0.00336175,0.855275 beta-lactamase_V106K,beta-lactamase_106,TEM-1,beta-lactamase,P62593,0.855275,NO,106,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.218,-3.831,2.613,5.23115,0.258,T,A,0.96,0.24,1.188,,72.73,OHP,-1.04933,0.221079,0.00304168,0.855275 beta-lactamase_X287M,beta-lactamase_287,TEM-1,beta-lactamase,P62593,0.855275,NO,287,X,M,XM,Stop,Hydrophobic,5.71,5.74,0.03,,132.5,149,16,141.9,162.9,21,,,,,,,,,,,,,HXO,-1.111,0.221079,,0.855275 gb1_E282Q,gb1_282,gb1,gb1,P06654,0.85535,NO,282,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.318,-3.174,1.856,,,,,,,1.075,,35.71,PAO,-1.573,0.177985,0.00209643,0.85535 WW_domain_E178N,WW_domain_178,Yap65,WW_domain,P46937,0.855356,NO,178,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.158,-3.225,2.067,5.22323,,,,,,,,,HAH,-1.299,0.153962,0.0016738,0.855356 beta-lactamase_0_E35S,beta-lactamase_0_35,TEM-1,beta-lactamase_0,P62593,0.855367,NO,35,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-0.869,-3.186,2.317,,0.15,H,A,1.04,0.21,0.664,,46.85,HAA,-1.88667,0.0500837,0.00174441,0.855367 beta-lactamase_0_L79M,beta-lactamase_0_79,TEM-1,beta-lactamase_0,P62593,0.855368,NO,79,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.842,-2.761,1.919,,0.007,H,A,0.55,-0.16,5.053,,50.35,HHP,-1.44333,0.0500837,0.000947397,0.855368 PSD95pdz3_E373W,PSD95pdz3_373,PSD95pdz3,PSD95pdz3,P31016,0.855388,NO,373,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.404,-5.004,3.6,5.79743,,,,,27.9833,,,,BAP,-1.57667,0.0758425,0.000387698,0.855388 beta-lactamase_625_T107G,beta-lactamase_625_107,TEM-1,beta-lactamase_625,P62593,0.855402,NO,107,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.117,-3.227,2.11,,,G,A,0.22,-0.06,3.676,,67.83,HPA,-1.265,0.213352,0.00239347,0.855402 PSD95pdz3_G345W,PSD95pdz3_345,PSD95pdz3,PSD95pdz3,P31016,0.855413,NO,345,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.008,-4.779,3.771,4.32868,,,,,13.165,,,,OOO,-1.084,0.0758425,0.000771806,0.855413 beta-lactamase_0_L248T,beta-lactamase_0_248,TEM-1,beta-lactamase_0,P62593,0.855458,NO,248,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.0500837,0.00428493,0.855458 beta-lactamase_L73H,beta-lactamase_73,TEM-1,beta-lactamase,P62593,0.855518,NO,73,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.507,-4.923,3.416,5.84139,,H,A,1.75,-0.64,2.09,,67.83,HHH,-1.487,0.221079,0.00488983,0.855518 beta-lactamase_P249C,beta-lactamase_249,TEM-1,beta-lactamase,P62593,0.855518,NO,249,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.312,-5.039,3.727,5.10655,0.256,S,B,0.99,0.04,0.479,,72.73,OOA,-1.81367,0.221079,0.00220169,0.855518 beta-lactamase_R81T,beta-lactamase_81,TEM-1,beta-lactamase,P62593,0.855518,NO,81,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.466,-3.547,2.081,5.12166,0.218,H,A,0.68,1.66,1.236,,50,PBH,-1.60667,0.221079,0.00499763,0.855518 beta-lactamase_0_Y262H,beta-lactamase_0_262,TEM-1,beta-lactamase_0,P62593,0.855533,NO,262,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.0500837,0.00853516,0.855533 kka2_1:8_E161L,kka2_1:8_161,Kka2,kka2_1:8,P00552,0.855536,NO,161,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.581,-3.558,1.977,,0.829,G,A,1.04,2.24,11.923,11.923,92.05,AAB,-1.861,0.100394,0.00760103,0.855536 kka2_1:8_E161L,kka2_1:8_161,Kka2,kka2_1:8,P00552,0.855536,NO,161,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.581,-3.558,1.977,,0.829,G,A,1.04,2.24,11.923,11.923,92.05,AAB,-1.861,0.100394,0.00760103,0.855536 kka2_1:8_L126R,kka2_1:8_126,Kka2,kka2_1:8,P00552,0.855562,NO,126,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.246,-4.098,2.852,,0.285,S,B,1.59,0.12,4.443,,51.89,PHA,-1.744,0.100394,0.0066485,0.855562 kka2_1:8_L126R,kka2_1:8_126,Kka2,kka2_1:8,P00552,0.855562,NO,126,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.246,-4.098,2.852,,0.285,S,B,1.59,0.12,4.443,,51.89,PHA,-1.744,0.100394,0.0066485,0.855562 beta-lactamase_2500_M66F,beta-lactamase_2500_66,TEM-1,beta-lactamase_2500,P62593,0.855588,NO,66,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.362,-3.731,2.369,,0.013,,A,0.55,-0.7,0.502,,73.08,OHH,-1.49567,0.361275,0.00412876,0.855588 beta-lactamase_0_L284P,beta-lactamase_0_284,TEM-1,beta-lactamase_0,P62593,0.855603,NO,284,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.981,,,,0.848,H,A,2.89,0.67,4.544,,77.62,PHH,-1.82133,0.0500837,0.0686156,0.855603 beta-lactamase_A185C,beta-lactamase_185,TEM-1,beta-lactamase,P62593,0.855654,NO,185,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.406,-4.699,3.293,4.89877,,H,A,2.34,-1.02,2.999,,65.03,HHP,-1.84033,0.221079,0.00467449,0.855654 beta-lactamase_39_L248E,beta-lactamase_39_248,TEM-1,beta-lactamase_39,P62593,0.855681,NO,248,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.0495842,0.00428493,0.855681 PSD95pdz3_G324A,PSD95pdz3_324,PSD95pdz3,PSD95pdz3,P31016,0.855681,NO,324,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.008,-2.534,1.526,4.98881,,,,,10.4525,,,,HOH,-1.293,0.0758425,0.00103462,0.855681 Pab1_A158E,Pab1_158,Pab1,Pab1,P04147,0.855693,NO,158,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.154,-3.361,2.207,,,,,,,1.197,,56.33,HHP,-1.40733,0.175299,0.000649733,0.855693 beta-lactamase_V214Q,beta-lactamase_214,TEM-1,beta-lactamase,P62593,0.855715,NO,214,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.299,-4.141,2.842,5.74008,0.375,S,A,1.19,-0.44,1.899,,74.48,BHH,-1.53733,0.221079,0.00628442,0.855715 beta-lactamase_G226Y,beta-lactamase_226,TEM-1,beta-lactamase,P62593,0.8558,NO,226,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.461,-4.462,3.001,5.70682,0.701,T,l,0.77,-0.25,3.199,,74.48,HOH,-1.42933,0.221079,0.00665294,0.8558 PSD95pdz3_E373H,PSD95pdz3_373,PSD95pdz3,PSD95pdz3,P31016,0.855831,NO,373,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.404,-3.912,2.508,5.79743,,,,,27.9833,,,,BAP,-1.57667,0.0758425,0.000387698,0.855831 kka2_1:8_A64E,kka2_1:8_64,Kka2,kka2_1:8,P00552,0.855868,NO,64,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.496,-2.982,1.486,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.100394,0.00705578,0.855868 kka2_1:8_A64E,kka2_1:8_64,Kka2,kka2_1:8,P00552,0.855868,NO,64,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.496,-2.982,1.486,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.100394,0.00705578,0.855868 beta-lactamase_2500_M127C,beta-lactamase_2500_127,TEM-1,beta-lactamase_2500,P62593,0.855886,NO,127,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-2.251,-5.009,2.758,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.361275,0.00437927,0.855886 PSD95pdz3_S339L,PSD95pdz3_339,PSD95pdz3,PSD95pdz3,P31016,0.855949,NO,339,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.519,-3.04,1.521,5.34493,,,,,12.2167,,,,HPH,-1.55767,0.0758425,0.00084982,0.855949 beta-lactamase_0_A133P,beta-lactamase_0_133,TEM-1,beta-lactamase_0,P62593,0.855972,NO,133,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.186,-3.811,2.625,,,H,A,0.46,-0.86,2.148,,67.83,HHP,-0.988333,0.0500837,0.00468022,0.855972 beta-lactamase_T69H,beta-lactamase_69,TEM-1,beta-lactamase,P62593,0.855983,NO,69,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-0.973,-4.716,3.743,5.16042,,G,A,0.69,-1.24,0.505,,93.01,PPH,-1.01833,0.221079,0.00127498,0.855983 kka2_1:2_R44C,kka2_1:2_44,Kka2,kka2_1:2,P00552,0.856012,NO,44,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.062,-5.189,3.127,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.295029,0.00745043,0.856012 beta-lactamase_0_Q88C,beta-lactamase_0_88,TEM-1,beta-lactamase_0,P62593,0.856021,NO,88,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.086,-5.138,3.052,,0.807,,B,0.64,2.03,0.4,,77.62,APH,-1.53433,0.0500837,0.00504167,0.856021 kka2_1:2_M148V,kka2_1:2_148,Kka2,kka2_1:2,P00552,0.856027,NO,148,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.847,-1.708,-0.139,,0.268,H,A,1.59,0.71,1.439,,64.39,BHA,-1.65467,0.295029,0.00982664,0.856027 PSD95pdz3_E373A,PSD95pdz3_373,PSD95pdz3,PSD95pdz3,P31016,0.856061,NO,373,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.404,-2.759,1.355,5.79743,,,,,27.9833,,,,BAP,-1.57667,0.0758425,0.000387698,0.856061 Pab1_N192W,Pab1_192,Pab1,Pab1,P04147,0.856143,NO,192,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-1.079,-5.365,4.286,,0.619,T,l,,2.28,,,,HPO,-1.231,0.175299,0.000273498,0.856143 Pab1_A141F,Pab1_141,Pab1,Pab1,P04147,0.856152,NO,141,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.461,-3.995,2.534,,0.34,H,A,0.52,-0.27,2.15,,79.03,BHH,-1.19433,0.175299,0.00165974,0.856152 beta-lactamase_F149E,beta-lactamase_149,TEM-1,beta-lactamase,P62593,0.85619,NO,149,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.299,-3.842,2.543,5.54789,0.195,H,A,1.1,0.11,1.863,,63.99,HHH,-1.46067,0.221079,0.00418462,0.85619 beta-lactamase_156_G52I,beta-lactamase_156_52,TEM-1,beta-lactamase_156,P62593,0.856193,NO,52,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.149,-4.163,3.014,,0.299,,l,0.29,-0.04,1.179,,64.69,POB,-1.66267,0.111618,0.00340138,0.856193 beta-lactamase_G52A,beta-lactamase_52,TEM-1,beta-lactamase,P62593,0.856206,NO,52,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.149,-2.316,1.167,5.12093,0.299,,l,0.77,-0.04,2.103,,64.69,POB,-1.66267,0.221079,0.00340138,0.856206 beta-lactamase_0_A225R,beta-lactamase_0_225,TEM-1,beta-lactamase_0,P62593,0.856217,NO,225,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.845,-2.864,1.019,,1,T,B,0.46,-0.38,11.722,11.722,74.48,OHO,-1.39967,0.0500837,0.00465057,0.856217 kka2_1:4_L184V,kka2_1:4_184,Kka2,kka2_1:4,P00552,0.856223,NO,184,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.496,-2.642,1.146,,0.489,E,B,1.59,-0.06,4.495,,63.26,AHH,-1.24833,0.168804,0.00518742,0.856223 WW_domain_D201Y,WW_domain_201,Yap65,WW_domain,P46937,0.856246,NO,201,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.369,-4.17,2.801,4.90312,,,,,,20.806,20.806,70.04,PAO,-1.456,0.153962,0.00248402,0.856246 beta-lactamase_2500_R273S,beta-lactamase_2500_273,TEM-1,beta-lactamase_2500,P62593,0.856376,NO,273,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.314,-3.326,1.012,,0.564,H,A,1.2,1.57,19.943,19.943,73.78,ABP,-1.841,0.361275,0.0077952,0.856376 beta-lactamase_0_M66D,beta-lactamase_0_66,TEM-1,beta-lactamase_0,P62593,0.856401,NO,66,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.362,-4.069,2.707,,0.013,,A,0.55,-0.7,1.204,,73.08,OHH,-1.49567,0.0500837,0.00412876,0.856401 kka2_1:2_R239F,kka2_1:2_239,Kka2,kka2_1:2,P00552,0.856414,NO,239,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.949,-4.366,1.417,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.295029,0.00835326,0.856414 PSD95pdz3_E352P,PSD95pdz3_352,PSD95pdz3,PSD95pdz3,P31016,0.856454,NO,352,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.587,-3.432,1.845,5.49659,,,,,24.2,2.525,,86.88,OAH,-1.314,0.0758425,0.000892231,0.856454 Pab1_K140I,Pab1_140,Pab1,Pab1,P04147,0.856468,NO,140,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.083,-3.827,2.744,,0.345,H,A,,-0.73,,,,PBH,-1.20767,0.175299,0.000337366,0.856468 beta-lactamase_2500_T187L,beta-lactamase_2500_187,TEM-1,beta-lactamase_2500,P62593,0.856494,NO,187,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.401,-2.278,0.877,,0.007,H,A,0.22,-1.19,3.91,,67.48,PPH,-1.69633,0.361275,0.00491782,0.856494 beta-lactamase_0_E169I,beta-lactamase_0_169,TEM-1,beta-lactamase_0,P62593,0.856515,NO,169,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.23,-3.986,2.756,,0.337,,A,1.04,1,3.516,,73.08,PAH,-1.16533,0.0500837,0.00400994,0.856515 gb1_E282T,gb1_282,gb1,gb1,P06654,0.856532,NO,282,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.318,-3.111,1.793,,,,,,,1.075,,35.71,PAO,-1.573,0.177985,0.00209643,0.856532 beta-lactamase_P105V,beta-lactamase_105,TEM-1,beta-lactamase,P62593,0.856704,NO,105,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.813,-3.554,2.741,5.08236,0.226,T,A,0.98,0.8,1.154,,63.29,POH,-1.01533,0.221079,0.0011981,0.856704 beta-lactamase_39_D155I,beta-lactamase_39_155,TEM-1,beta-lactamase_39,P62593,0.856717,NO,155,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.889,-4.06,3.171,,0.049,,B,0.75,-0.9,3.208,,64.69,OAB,-1.62267,0.0495842,0.00135315,0.856717 beta-lactamase_D48C,beta-lactamase_48,TEM-1,beta-lactamase,P62593,0.856718,NO,48,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.101,-5.125,4.024,4.89966,0.189,E,B,0.23,0.21,1.281,,50.35,HAH,-1.62467,0.221079,0.0027273,0.856718 kka2_1:2_V36A,kka2_1:2_36,Kka2,kka2_1:2,P00552,0.856727,NO,36,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-0.898,-2.963,2.065,,0.292,E,B,1.48,0.21,1.064,,52.27,HHH,-1.484,0.295029,0.00245633,0.856727 beta-lactamase_0_L191Q,beta-lactamase_0_191,TEM-1,beta-lactamase_0,P62593,0.856742,NO,191,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.087,-4.183,3.096,,,H,A,0.55,0.09,12.255,12.255,63.29,BHH,-1.445,0.0500837,0.00263549,0.856742 beta-lactamase_39_A282P,beta-lactamase_39_282,TEM-1,beta-lactamase_39,P62593,0.856744,NO,282,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.0495842,0.0449821,0.856744 Pab1_K140T,Pab1_140,Pab1,Pab1,P04147,0.856745,NO,140,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.083,-3.239,2.156,,0.345,H,A,,-0.73,,,,PBH,-1.20767,0.175299,0.000337366,0.856745 beta-lactamase_P12D,beta-lactamase_12,TEM-1,beta-lactamase,P62593,0.856756,NO,12,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-2.016,-3.69,1.674,,,,,,,2.88,,72.73,HOH,-2.05167,0.221079,0.00241653,0.856756 beta-lactamase_0_D177S,beta-lactamase_0_177,TEM-1,beta-lactamase_0,P62593,0.856778,NO,177,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.967,-3.186,2.219,,0.006,T,L,0.75,-1.02,3.536,,64.69,BAP,-0.873667,0.0500837,0.000864022,0.856778 kka2_1:1_V214G,kka2_1:1_214,Kka2,kka2_1:1,P00552,0.856811,NO,214,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.261,-3.813,2.552,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.520039,0.00692782,0.856811 beta-lactamase_A124G,beta-lactamase_124,TEM-1,beta-lactamase,P62593,0.856834,NO,124,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.181,-3.186,2.005,4.58507,,H,A,0.58,-0.9,2.273,,64.34,HHH,-1.152,0.221079,0.00481399,0.856834 beta-lactamase_P249H,beta-lactamase_249,TEM-1,beta-lactamase,P62593,0.856872,NO,249,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.312,-4.784,3.472,5.10655,0.256,S,B,0.99,0.04,0.479,,72.73,OOA,-1.81367,0.221079,0.00220169,0.856872 beta-lactamase_I3V,beta-lactamase_3,TEM-1,beta-lactamase,P62593,0.856881,NO,3,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-2.143,-2.808,0.665,,,,,,,3.946,,93.01,PHP,-2.21633,0.221079,0.00349304,0.856881 gb1_G235S,gb1_235,gb1,gb1,P06654,0.856924,NO,235,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.419,-2.853,1.434,,,,,,,0.476,,11.83,POB,-1.86433,0.177985,0.00297491,0.856924 beta-lactamase_0_I54C,beta-lactamase_0_54,TEM-1,beta-lactamase_0,P62593,0.85695,NO,54,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-2.838,-5.056,2.218,,0.669,E,B,0.48,-0.14,0.541,,73.78,BHH,-2.337,0.0500837,0.00403589,0.85695 kka2_1:2_N58D,kka2_1:2_58,Kka2,kka2_1:2,P00552,0.856997,NO,58,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-2.641,-2.6,-0.041,,0.131,S,A,0.43,0.72,5.729,,71.59,HPA,-1.83033,0.295029,0.00793425,0.856997 beta-lactamase_0_L146Q,beta-lactamase_0_146,TEM-1,beta-lactamase_0,P62593,0.857001,NO,146,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.462,-4.29,2.828,,0.007,H,A,0.55,-0.56,2.051,,64.69,AHP,-1.656,0.0500837,0.00474542,0.857001 kka2_1:4_T73G,kka2_1:4_73,Kka2,kka2_1:4,P00552,0.857034,NO,73,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.51,-3.619,1.109,,0.309,H,A,0.22,0.35,1.53,,56.06,PPO,-2.02333,0.168804,0.00628605,0.857034 beta-lactamase_0_V259R,beta-lactamase_0_259,TEM-1,beta-lactamase_0,P62593,0.857053,NO,259,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.0500837,0.0070773,0.857053 kka2_1:2_P194T,kka2_1:2_194,Kka2,kka2_1:2,P00552,0.857064,NO,194,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.846,-3.444,2.598,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.295029,0.00314194,0.857064 beta-lactamase_P181A,beta-lactamase_181,TEM-1,beta-lactamase,P62593,0.857097,NO,181,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.813,-2.357,1.544,5.14752,,H,A,1.1,-1.14,1.357,,61.54,HOH,-1.795,0.221079,0.000703122,0.857097 beta-lactamase_39_W227I,beta-lactamase_39_227,TEM-1,beta-lactamase_39,P62593,0.857103,NO,227,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-0.982,-3.985,3.003,,0.272,,B,0.47,-0.29,1.37,,74.48,OHH,-1.595,0.0495842,0.00226019,0.857103 beta-lactamase_F149C,beta-lactamase_149,TEM-1,beta-lactamase,P62593,0.857106,NO,149,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.299,-4.94,3.641,5.54789,0.195,H,A,1.1,0.11,1.863,,63.99,HHH,-1.46067,0.221079,0.00418462,0.857106 beta-lactamase_0_E272W,beta-lactamase_0_272,TEM-1,beta-lactamase_0,P62593,0.857137,NO,272,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.0500837,0.00545371,0.857137 beta-lactamase_0_L199D,beta-lactamase_0_199,TEM-1,beta-lactamase_0,P62593,0.857239,NO,199,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-2.942,-3.009,0.067,,0.832,H,A,0.55,0.42,10.85,10.85,77.62,PHH,-2.32933,0.0500837,0.0048649,0.857239 beta-lactamase_E87C,beta-lactamase_87,TEM-1,beta-lactamase,P62593,0.857261,NO,87,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.421,-5.162,3.741,5.41929,0.048,,B,0.52,0.92,1.754,,64.69,PAP,-1.969,0.221079,0.00337888,0.857261 beta-lactamase_V72C,beta-lactamase_72,TEM-1,beta-lactamase,P62593,0.857261,NO,72,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.658,-4.8,3.142,5.80324,,H,A,2.78,-1.03,2.964,,65.73,BHH,-1.32167,0.221079,0.00501194,0.857261 beta-lactamase_0_P105S,beta-lactamase_0_105,TEM-1,beta-lactamase_0,P62593,0.857294,NO,105,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.813,-2.526,1.713,,0.226,T,A,0.52,0.8,3.48,,63.29,POH,-1.01533,0.0500837,0.0011981,0.857294 beta-lactamase_A183D,beta-lactamase_183,TEM-1,beta-lactamase,P62593,0.857304,NO,183,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.231,-2.686,1.455,4.84712,0.155,H,A,0.55,-0.91,12.189,,77.62,HHH,-1.53367,0.221079,0.00296631,0.857304 gb1_G264V,gb1_264,gb1,gb1,P06654,0.857315,NO,264,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.833,-3.068,1.235,,,,,,,0.864,,44.87,POH,-1.61267,0.177985,0.0049716,0.857315 gb1_T237R,gb1_237,gb1,gb1,P06654,0.857315,NO,237,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.736,-3.534,1.798,,,,,,,0.218,,11.83,BPH,-2.27833,0.177985,0.00275316,0.857315 kka2_1:8_R140G,kka2_1:8_140,Kka2,kka2_1:8,P00552,0.857342,NO,140,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.351,-2.695,1.344,,0.12,H,A,0.16,0.2,2.874,,53.03,BBH,-1.885,0.100394,0.00430167,0.857342 kka2_1:8_R140G,kka2_1:8_140,Kka2,kka2_1:8,P00552,0.857342,NO,140,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.351,-2.695,1.344,,0.12,H,A,0.16,0.2,2.874,,53.03,BBH,-1.885,0.100394,0.00430167,0.857342 beta-lactamase_0_R257Q,beta-lactamase_0_257,TEM-1,beta-lactamase_0,P62593,0.857383,NO,257,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.0500837,0.00756629,0.857383 beta-lactamase_0_D207F,beta-lactamase_0_207,TEM-1,beta-lactamase_0,P62593,0.857454,NO,207,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.064,-4.437,2.373,,0.409,H,A,0.75,0.12,5.277,,77.62,HAH,-1.77033,0.0500837,0.00592942,0.857454 beta-lactamase_156_T158C,beta-lactamase_156_158,TEM-1,beta-lactamase_156,P62593,0.857474,NO,158,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.116,-4.748,3.632,,0.036,,B,0.22,-0.85,3.771,,69.58,HPB,-1.269,0.111618,0.00341825,0.857474 PSD95pdz3_V386Y,PSD95pdz3_386,PSD95pdz3,PSD95pdz3,P31016,0.857476,NO,386,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.465,-3.619,2.154,5.18836,,,,,17.5429,,,,PHP,-1.463,0.0758425,0.000184509,0.857476 beta-lactamase_A148P,beta-lactamase_148,TEM-1,beta-lactamase,P62593,0.85749,NO,148,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.757,-3.925,2.168,5.28111,0.379,H,A,0.52,-0.55,2.117,,72.73,PHH,-1.40167,0.221079,0.00547053,0.85749 kka2_1:2_M148L,kka2_1:2_148,Kka2,kka2_1:2,P00552,0.857519,NO,148,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.847,-2.054,0.207,,0.268,H,A,1.59,0.71,1.439,,64.39,BHA,-1.65467,0.295029,0.00982664,0.857519 beta-lactamase_0_G265R,beta-lactamase_0_265,TEM-1,beta-lactamase_0,P62593,0.857553,NO,265,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.0500837,0.00811926,0.857553 kka2_1:8_E59D,kka2_1:8_59,Kka2,kka2_1:8,P00552,0.857571,NO,59,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-0.952,-2.395,1.443,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.100394,0.00280355,0.857571 kka2_1:8_E59D,kka2_1:8_59,Kka2,kka2_1:8,P00552,0.857571,NO,59,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-0.952,-2.395,1.443,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.100394,0.00280355,0.857571 kka2_1:2_E149G,kka2_1:2_149,Kka2,kka2_1:2,P00552,0.857587,NO,149,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.994,-3.566,1.572,,0.674,H,A,1.04,1.63,15.361,15.361,71.59,HAH,-1.59667,0.295029,0.00803343,0.857587 beta-lactamase_E46I,beta-lactamase_46,TEM-1,beta-lactamase,P62593,0.857602,NO,46,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.94,-2.064,0.124,5.36461,0.021,E,B,1.51,0.14,0.373,,59.44,HAH,-2.079,0.221079,0.00427568,0.857602 beta-lactamase_K30H,beta-lactamase_30,TEM-1,beta-lactamase,P62593,0.857602,NO,30,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-2.307,-4.558,2.251,5.30605,0.142,H,A,1.82,-0.65,2.434,,93.01,HBH,-2.32833,0.221079,0.00448593,0.857602 beta-lactamase_L38P,beta-lactamase_38,TEM-1,beta-lactamase,P62593,0.857602,NO,38,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.343,-2.934,1.591,5.23728,0.088,H,A,1.75,0.2,1.986,,64.34,PHO,-1.78033,0.221079,0.00373244,0.857602 beta-lactamase_M66A,beta-lactamase_66,TEM-1,beta-lactamase,P62593,0.857602,NO,66,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.362,-3.154,1.792,5.29561,0.013,,A,1.3,-0.7,1.319,,73.08,OHH,-1.49567,0.221079,0.00412876,0.857602 beta-lactamase_0_S96I,beta-lactamase_0_96,TEM-1,beta-lactamase_0,P62593,0.857625,NO,96,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.27,-3.225,0.955,,0.368,,b,0.27,0.39,2.516,,73.78,HPP,-2.019,0.0500837,0.00551835,0.857625 beta-lactamase_0_D207L,beta-lactamase_0_207,TEM-1,beta-lactamase_0,P62593,0.85763,NO,207,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.064,-3.704,1.64,,0.409,H,A,0.75,0.12,5.277,,77.62,HAH,-1.77033,0.0500837,0.00592942,0.85763 beta-lactamase_I244A,beta-lactamase_244,TEM-1,beta-lactamase,P62593,0.857639,NO,244,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.555,-3.008,1.453,5.35885,,E,B,0.01,-0.84,0.379,,77.62,HHH,-1.385,0.221079,0.00605379,0.857639 gb1_L233M,gb1_233,gb1,gb1,P06654,0.857705,NO,233,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-2.678,-3.974,1.296,,,,,,,0.822,,45.54,HHP,-2.30267,0.177985,0.00266958,0.857705 beta-lactamase_I11S,beta-lactamase_11,TEM-1,beta-lactamase,P62593,0.857746,NO,11,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.745,-2.611,0.866,,,,,,,3.135,,66.08,HHO,-1.79467,0.221079,0.00261325,0.857746 beta-lactamase_F6A,beta-lactamase_6,TEM-1,beta-lactamase,P62593,0.857781,NO,6,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.847,-2.288,0.441,,,,,,,1.276,,67.83,BHB,-2.076,0.221079,0.00261627,0.857781 beta-lactamase_R63A,beta-lactamase_63,TEM-1,beta-lactamase,P62593,0.857781,NO,63,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-0.943,-3.103,2.16,5.49979,0.218,,B,0.45,-0.31,0.677,,44.06,ABH,-0.992333,0.221079,0.00126938,0.857781 kka2_1:2_S114F,kka2_1:2_114,Kka2,kka2_1:2,P00552,0.85779,NO,114,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.527,-4.392,1.865,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.295029,0.00705262,0.85779 beta-lactamase_2500_H24L,beta-lactamase_2500_24,TEM-1,beta-lactamase_2500,P62593,0.857839,NO,24,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-2.481,-3.404,0.923,,,,,,,0.467,,93.01,OBO,-2.0035,0.361275,0.00238894,0.857839 kka2_1:1_E17Q,kka2_1:1_17,Kka2,kka2_1:1,P00552,0.857905,NO,17,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.154,-2.533,0.379,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.520039,0.00688738,0.857905 beta-lactamase_S264C,beta-lactamase_264,TEM-1,beta-lactamase,P62593,0.857927,NO,264,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.985,-3.353,1.368,4.67475,0.04,,B,0.25,0.29,34.251,34.251,73.78,OPP,-2.19867,0.221079,0.0119399,0.857927 beta-lactamase_39_A123R,beta-lactamase_39_123,TEM-1,beta-lactamase_39,P62593,0.857948,NO,123,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.834,-3.776,2.942,,0.039,H,A,0.46,-0.72,0.705,,41.26,PHH,-1.47367,0.0495842,0.0010157,0.857948 beta-lactamase_0_E169K,beta-lactamase_0_169,TEM-1,beta-lactamase_0,P62593,0.85795,NO,169,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.23,-3.226,1.996,,0.337,,A,1.04,1,3.516,,73.08,PAH,-1.16533,0.0500837,0.00400994,0.85795 beta-lactamase_39_I285D,beta-lactamase_39_285,TEM-1,beta-lactamase_39,P62593,0.857955,NO,285,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.0495842,0.101555,0.857955 beta-lactamase_0_E195A,beta-lactamase_0_195,TEM-1,beta-lactamase_0,P62593,0.857966,NO,195,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.186,-2.778,0.592,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.0500837,0.00496565,0.857966 beta-lactamase_0_R91L,beta-lactamase_0_91,TEM-1,beta-lactamase_0,P62593,0.858023,NO,91,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.392,-3.471,2.079,,0.444,,B,1.2,0.96,4.557,,50.35,OBB,-1.73367,0.0500837,0.00380226,0.858023 kka2_1:1_A35E,kka2_1:1_35,Kka2,kka2_1:1,P00552,0.858102,NO,35,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.127,-2.492,0.365,,0.107,E,B,0.46,1.05,8.405,8.405,71.59,HHH,-1.31767,0.520039,0.00630016,0.858102 kka2_1:1_V198A,kka2_1:1_198,Kka2,kka2_1:1,P00552,0.858115,NO,198,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.719,-1.379,-0.34,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.520039,0.00835002,0.858115 beta-lactamase_0_L137Q,beta-lactamase_0_137,TEM-1,beta-lactamase_0,P62593,0.858121,NO,137,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.03,-4.147,3.117,,,H,A,0.55,-0.38,0.328,,42.31,HHP,-1.58933,0.0500837,0.00278599,0.858121 beta-lactamase_625_H110I,beta-lactamase_625_110,TEM-1,beta-lactamase_625,P62593,0.85813,NO,110,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-1.706,-4.048,2.342,,0.341,G,a,0.17,1.08,31.31,31.31,64.69,BBH,-1.73333,0.213352,0.00441499,0.85813 kka2_1:2_R173S,kka2_1:2_173,Kka2,kka2_1:2,P00552,0.858132,NO,173,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.407,-3.482,1.075,,0.308,H,A,0.16,-0.13,15.389,15.389,65.53,HBH,-1.70533,0.295029,0.00784999,0.858132 hsp90_M589A,hsp90_589,hsp90,hsp90,P02829,0.858155,NO,589,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-3.858,-2.456,0,4.72723,0.032,H,A,0.84,0.31,,,,PHA,-3.24233,0.368192,0.000222939,0.858155 beta-lactamase_0_L47T,beta-lactamase_0_47,TEM-1,beta-lactamase_0,P62593,0.858178,NO,47,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.876,-2.727,0.851,,0.007,E,B,0.55,0.2,1.024,,67.83,AHA,-1.639,0.0500837,0.00439844,0.858178 PSD95pdz3_F340I,PSD95pdz3_340,PSD95pdz3,PSD95pdz3,P31016,0.858186,NO,340,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.524,-3.017,1.493,5.79283,,,,,11.8045,,,,PHH,-1.55767,0.0758425,0.000836987,0.858186 beta-lactamase_R63Y,beta-lactamase_63,TEM-1,beta-lactamase,P62593,0.858199,NO,63,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-0.943,-4.16,3.217,5.49979,0.218,,B,0.45,-0.31,0.677,,44.06,ABH,-0.992333,0.221079,0.00126938,0.858199 beta-lactamase_F14W,beta-lactamase_14,TEM-1,beta-lactamase,P62593,0.858236,NO,14,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-2.736,-5.168,2.432,,,,,,,1.537,,93.01,HHH,-2.26133,0.221079,0.00277095,0.858236 beta-lactamase_V21I,beta-lactamase_21,TEM-1,beta-lactamase,P62593,0.858236,NO,21,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.873,-3.249,1.376,,,,,,,0.688,,93.01,OHH,-2.09633,0.221079,0.0028612,0.858236 beta-lactamase_S96P,beta-lactamase_96,TEM-1,beta-lactamase,P62593,0.858263,NO,96,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.27,-2.878,0.608,5.29889,0.368,,b,0.25,0.39,32.348,32.348,73.78,HPP,-2.019,0.221079,0.00551835,0.858263 beta-lactamase_625_A215R,beta-lactamase_625_215,TEM-1,beta-lactamase_625,P62593,0.85831,NO,215,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.503,-3.862,2.359,,,,a,0.46,-0.93,3.583,,74.48,HHO,-1.42633,0.213352,0.00544007,0.85831 beta-lactamase_0_T27R,beta-lactamase_0_27,TEM-1,beta-lactamase_0,P62593,0.858377,NO,27,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.905,-3.861,1.956,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.0500837,0.00306559,0.858377 kka2_1:4_I254K,kka2_1:4_254,Kka2,kka2_1:4,P00552,0.858401,NO,254,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.933,-3.795,1.862,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.168804,0.0132375,0.858401 beta-lactamase_0_G141R,beta-lactamase_0_141,TEM-1,beta-lactamase_0,P62593,0.858467,NO,141,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.828,-3.94,3.112,,0.575,T,l,0.29,-0.28,0.722,,64.69,HOO,-1.08933,0.0500837,0.0012419,0.858467 Pab1_T145N,Pab1_145,Pab1,Pab1,P04147,0.858481,NO,145,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.067,-3.265,2.198,,0.237,H,A,0.3,0.69,,,,APH,-1.135,0.175299,0.000331088,0.858481 gb1_T237Y,gb1_237,gb1,gb1,P06654,0.858482,NO,237,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.736,-4.062,2.326,,,,,,,0.218,,11.83,BPH,-2.27833,0.177985,0.00275316,0.858482 kka2_1:8_V46W,kka2_1:8_46,Kka2,kka2_1:8,P00552,0.858482,NO,46,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-2.62,-5.568,2.948,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.100394,0.00631301,0.858482 kka2_1:8_V46W,kka2_1:8_46,Kka2,kka2_1:8,P00552,0.858482,NO,46,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-2.62,-5.568,2.948,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.100394,0.00631301,0.858482 Pab1_F149Y,Pab1_149,Pab1,Pab1,P04147,0.858545,NO,149,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.149,-2.855,1.706,,0.183,T,A,1.33,1.09,,,,HHO,-1.27767,0.175299,0.000325688,0.858545 beta-lactamase_0_V82G,beta-lactamase_0_82,TEM-1,beta-lactamase_0,P62593,0.858552,NO,82,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.325,-2.644,1.319,,0.267,H,A,0.44,0.08,1.893,,93.01,BHA,-1.28567,0.0500837,0.00397046,0.858552 beta-lactamase_0_D83H,beta-lactamase_0_83,TEM-1,beta-lactamase_0,P62593,0.858608,NO,83,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.066,-4.503,3.437,,0.354,H,A,0.75,0.22,0.617,,48.95,HAH,-1.34733,0.0500837,0.00205968,0.858608 beta-lactamase_625_L47E,beta-lactamase_625_47,TEM-1,beta-lactamase_625,P62593,0.858628,NO,47,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.876,-2.999,1.123,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.213352,0.00439844,0.858628 kka2_1:8_E169W,kka2_1:8_169,Kka2,kka2_1:8,P00552,0.858659,NO,169,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.996,-5.529,3.533,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.100394,0.00730086,0.858659 kka2_1:8_E169W,kka2_1:8_169,Kka2,kka2_1:8,P00552,0.858659,NO,169,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.996,-5.529,3.533,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.100394,0.00730086,0.858659 beta-lactamase_S240N,beta-lactamase_240,TEM-1,beta-lactamase,P62593,0.858696,NO,240,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.537,-2.728,1.191,4.75024,,,B,0.74,-0.74,0.357,,65.38,OPB,-1.263,0.221079,0.00591201,0.858696 beta-lactamase_P165S,beta-lactamase_165,TEM-1,beta-lactamase,P62593,0.858704,NO,165,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.373,-3.19,1.817,5.33889,0.203,T,A,0.99,-0.31,0.414,,73.78,AOA,-1.359,0.221079,0.00549538,0.858704 kka2_1:1_D52G,kka2_1:1_52,Kka2,kka2_1:1,P00552,0.858742,NO,52,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.271,-3.385,1.114,,0.22,E,B,0.75,0.8,2.64,,71.59,PAH,-2.38367,0.520039,0.00175694,0.858742 beta-lactamase_0_A124P,beta-lactamase_0_124,TEM-1,beta-lactamase_0,P62593,0.858744,NO,124,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.181,-3.759,2.578,,,H,A,0.46,-0.9,1.876,,64.34,HHH,-1.152,0.0500837,0.00481399,0.858744 kka2_1:8_L193R,kka2_1:8_193,Kka2,kka2_1:8,P00552,0.858861,NO,193,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.983,-3.937,2.954,,,G,A,1.59,-1.03,2.234,,65.53,OHO,-0.965333,0.100394,0.00480179,0.858861 kka2_1:8_L193R,kka2_1:8_193,Kka2,kka2_1:8,P00552,0.858861,NO,193,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.983,-3.937,2.954,,,G,A,1.59,-1.03,2.234,,65.53,OHO,-0.965333,0.100394,0.00480179,0.858861 kka2_1:4_G10I,kka2_1:4_10,Kka2,kka2_1:4,P00552,0.858902,NO,10,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.921,-4.096,2.175,,,,,,,1.862,,71.59,HOP,-2.10733,0.168804,0.00289233,0.858902 beta-lactamase_R238D,beta-lactamase_238,TEM-1,beta-lactamase,P62593,0.858919,NO,238,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.002,-3.676,1.674,5.87663,0.564,T,L,0.45,1.09,4.195,,72.73,ABO,-1.62633,0.221079,0.00743256,0.858919 beta-lactamase_0_D177F,beta-lactamase_0_177,TEM-1,beta-lactamase_0,P62593,0.858936,NO,177,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.967,-4.34,3.373,,0.006,T,L,0.75,-1.02,3.536,,64.69,BAP,-0.873667,0.0500837,0.000864022,0.858936 kka2_1:1_E96Q,kka2_1:1_96,Kka2,kka2_1:1,P00552,0.858947,NO,96,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.573,-3.937,1.364,,0.476,,B,1.52,-0.65,1.254,,71.59,OAH,-2.143,0.520039,0.00369441,0.858947 beta-lactamase_E62G,beta-lactamase_62,TEM-1,beta-lactamase,P62593,0.858953,NO,62,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.193,-2.548,1.355,5.93066,0.342,S,B,1.52,-0.3,3.139,,73.08,AAB,-1.417,0.221079,0.00264802,0.858953 beta-lactamase_0_D177R,beta-lactamase_0_177,TEM-1,beta-lactamase_0,P62593,0.859051,NO,177,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.967,-3.931,2.964,,0.006,T,L,0.75,-1.02,3.536,,64.69,BAP,-0.873667,0.0500837,0.000864022,0.859051 beta-lactamase_2500_R159S,beta-lactamase_2500_159,TEM-1,beta-lactamase_2500,P62593,0.859061,NO,159,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-0.94,-3.411,2.471,,0.316,,B,1.2,-0.55,2.341,,64.34,PBH,-1.011,0.361275,0.00108472,0.859061 beta-lactamase_2500_L150C,beta-lactamase_2500_150,TEM-1,beta-lactamase_2500,P62593,0.859088,NO,150,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.326,-4.732,3.406,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.361275,0.00463171,0.859088 kka2_1:2_L7F,kka2_1:2_7,Kka2,kka2_1:2,P00552,0.859148,NO,7,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.926,-3.787,1.861,,,,,,,3.012,,71.59,OHB,-2.12333,0.295029,0.00269456,0.859148 kka2_1:8_V186T,kka2_1:8_186,Kka2,kka2_1:8,P00552,0.859164,NO,186,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.011,-3.386,2.375,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.100394,0.00409703,0.859164 kka2_1:8_V186T,kka2_1:8_186,Kka2,kka2_1:8,P00552,0.859164,NO,186,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.011,-3.386,2.375,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.100394,0.00409703,0.859164 kka2_1:2_D134L,kka2_1:2_134,Kka2,kka2_1:2,P00552,0.85921,NO,134,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.969,-2.811,1.842,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.295029,0.00270812,0.85921 kka2_1:4_V198S,kka2_1:4_198,Kka2,kka2_1:4,P00552,0.859265,NO,198,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.719,-2.746,1.027,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.168804,0.00835002,0.859265 beta-lactamase_0_W227C,beta-lactamase_0_227,TEM-1,beta-lactamase_0,P62593,0.859291,NO,227,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-0.982,-4.932,3.95,,0.272,,B,0.47,-0.29,3.782,,74.48,OHH,-1.595,0.0500837,0.00226019,0.859291 beta-lactamase_0_P143E,beta-lactamase_0_143,TEM-1,beta-lactamase_0,P62593,0.859316,NO,143,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.967,-3.58,2.613,,0.075,H,A,0.52,-0.37,11.868,11.868,66.78,OOB,-1.354,0.0500837,0.00114551,0.859316 beta-lactamase_0_L28F,beta-lactamase_0_28,TEM-1,beta-lactamase_0,P62593,0.859322,NO,28,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.579,-3.916,2.337,,0.277,H,A,0.55,-0.16,9.35,9.35,93.01,PHH,-2.11333,0.0500837,0.00359321,0.859322 beta-lactamase_D113F,beta-lactamase_113,TEM-1,beta-lactamase,P62593,0.859347,NO,113,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.829,-4.448,2.619,6.04499,0.665,T,A,0.23,0.91,21.104,21.104,73.08,PAO,-1.703,0.221079,0.00474112,0.859347 beta-lactamase_L167N,beta-lactamase_167,TEM-1,beta-lactamase,P62593,0.859347,NO,167,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.138,-4.008,2.87,5.13111,0.015,G,A,0.08,-0.63,0.4,,64.69,AHP,-1.30767,0.221079,0.00303566,0.859347 beta-lactamase_R202I,beta-lactamase_202,TEM-1,beta-lactamase,P62593,0.859347,NO,202,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.292,-4.027,2.735,5.16273,0.188,H,A,0.68,0.62,1.918,,77.62,PBP,-1.54767,0.221079,0.00321899,0.859347 kka2_1:8_E63D,kka2_1:8_63,Kka2,kka2_1:8,P00552,0.859366,NO,63,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-0.762,-2.822,2.06,,0.043,H,A,1.52,-0.43,,,,AAH,-1.283,0.100394,0.00118399,0.859366 kka2_1:8_E63D,kka2_1:8_63,Kka2,kka2_1:8,P00552,0.859366,NO,63,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-0.762,-2.822,2.06,,0.043,H,A,1.52,-0.43,,,,AAH,-1.283,0.100394,0.00118399,0.859366 kka2_1:4_L243W,kka2_1:4_243,Kka2,kka2_1:4,P00552,0.859369,NO,243,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-2.651,-5.55,2.899,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.168804,0.00884927,0.859369 beta-lactamase_0_N168M,beta-lactamase_0_168,TEM-1,beta-lactamase_0,P62593,0.859373,NO,168,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-1.029,-4.683,3.654,,0.113,G,A,0.61,-0.4,0.881,,44.41,HPA,-1.13233,0.0500837,0.00288667,0.859373 PSD95pdz3_G351W,PSD95pdz3_351,PSD95pdz3,PSD95pdz3,P31016,0.859401,NO,351,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.008,-4.779,3.771,5.44798,,,,,20.7625,,,,POA,-1.37133,0.0758425,0.000691282,0.859401 kka2_1:8_L92T,kka2_1:8_92,Kka2,kka2_1:8,P00552,0.859416,NO,92,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.893,-3.472,2.579,,0.007,E,B,1.59,-0.19,1.719,,63.26,HHH,-0.962,0.100394,0.00307177,0.859416 kka2_1:8_L92T,kka2_1:8_92,Kka2,kka2_1:8,P00552,0.859416,NO,92,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.893,-3.472,2.579,,0.007,E,B,1.59,-0.19,1.719,,63.26,HHH,-0.962,0.100394,0.00307177,0.859416 beta-lactamase_A276I,beta-lactamase_276,TEM-1,beta-lactamase,P62593,0.859514,NO,276,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.144,-2.759,1.615,5.1387,0.117,H,A,0.52,-0.84,1.283,,44.06,HHA,-1.47,0.221079,0.0191712,0.859514 beta-lactamase_2500_A40T,beta-lactamase_2500_40,TEM-1,beta-lactamase_2500,P62593,0.859588,NO,40,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.402,-2.653,1.251,,0.155,S,B,0.46,0.21,0.953,,73.78,OHB,-1.40267,0.361275,0.00490026,0.859588 kka2_1:8_L67F,kka2_1:8_67,Kka2,kka2_1:8,P00552,0.859592,NO,67,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.741,-3.645,2.904,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.100394,0.00102787,0.859592 kka2_1:8_L67F,kka2_1:8_67,Kka2,kka2_1:8,P00552,0.859592,NO,67,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.741,-3.645,2.904,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.100394,0.00102787,0.859592 beta-lactamase_0_I171E,beta-lactamase_0_171,TEM-1,beta-lactamase_0,P62593,0.859608,NO,171,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-2.431,-3.643,1.212,,0.361,,B,0.48,0.53,16.954,16.954,77.62,HHO,-1.55533,0.0500837,0.00623355,0.859608 gb1_F256Y,gb1_256,gb1,gb1,P06654,0.859641,NO,256,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.241,-2.814,1.573,,,,,,,,,,HHB,-2.04767,0.177985,0.00435993,0.859641 gb1_Q258V,gb1_258,gb1,gb1,P06654,0.859641,NO,258,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.095,-3.425,1.33,,,,,,,0.86,,37.28,BPH,-1.88333,0.177985,0.00437595,0.859641 beta-lactamase_G52E,beta-lactamase_52,TEM-1,beta-lactamase,P62593,0.859645,NO,52,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.149,-3.424,2.275,5.12093,0.299,,l,0.77,-0.04,2.103,,64.69,POB,-1.66267,0.221079,0.00340138,0.859645 beta-lactamase_2500_G226A,beta-lactamase_2500_226,TEM-1,beta-lactamase_2500,P62593,0.859705,NO,226,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.461,-2.638,1.177,,0.701,T,l,0.29,-0.25,5.086,,74.48,HOH,-1.42933,0.361275,0.00665294,0.859705 beta-lactamase_R41E,beta-lactamase_41,TEM-1,beta-lactamase,P62593,0.859717,NO,41,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-0.942,-3.241,2.299,5.69185,0.321,E,B,0.91,-0.07,4.357,,65.03,HBH,-1.30267,0.221079,0.00123327,0.859717 beta-lactamase_W286Y,beta-lactamase_286,TEM-1,beta-lactamase,P62593,0.859717,NO,286,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-1.111,-3.08,1.969,6.64456,0.492,,?,0.01,0.6,,,,BHX,-1.478,0.221079,,0.859717 kka2_1:4_I196M,kka2_1:4_196,Kka2,kka2_1:4,P00552,0.859739,NO,196,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-2.115,-3.213,1.098,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.168804,0.0107273,0.859739 beta-lactamase_0_K71Q,beta-lactamase_0_71,TEM-1,beta-lactamase_0,P62593,0.859802,NO,71,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-0.8,-3.449,2.649,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.0500837,0.00103192,0.859802 PSD95pdz3_I377P,PSD95pdz3_377,PSD95pdz3,PSD95pdz3,P31016,0.859819,NO,377,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.873,-3.826,1.953,4.9532,,,,,19.185,2.364,,87.71,HHH,-1.49567,0.0758425,0.000795475,0.859819 beta-lactamase_W227Y,beta-lactamase_227,TEM-1,beta-lactamase,P62593,0.859836,NO,227,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-0.982,-3.356,2.374,4.86393,0.272,,B,0.99,-0.29,1.37,,74.48,OHH,-1.595,0.221079,0.00226019,0.859836 beta-lactamase_E87A,beta-lactamase_87,TEM-1,beta-lactamase,P62593,0.859849,NO,87,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.421,-3.209,1.788,5.41929,0.048,,B,0.52,0.92,1.754,,64.69,PAP,-1.969,0.221079,0.00337888,0.859849 beta-lactamase_39_V42G,beta-lactamase_39_42,TEM-1,beta-lactamase_39,P62593,0.859895,NO,42,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.564,-2.773,1.209,,0.017,E,B,0.44,-0.51,1.86,,63.99,BHO,-1.042,0.0495842,0.00404515,0.859895 kka2_1:8_I207L,kka2_1:8_207,Kka2,kka2_1:8,P00552,0.859895,NO,207,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.175,-2.098,0.923,,0.293,,B,1.52,-1.12,1.306,,56.06,HHA,-1.07733,0.100394,0.00611824,0.859895 kka2_1:8_I207L,kka2_1:8_207,Kka2,kka2_1:8,P00552,0.859895,NO,207,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.175,-2.098,0.923,,0.293,,B,1.52,-1.12,1.306,,56.06,HHA,-1.07733,0.100394,0.00611824,0.859895 kka2_1:8_P128Q,kka2_1:8_128,Kka2,kka2_1:8,P00552,0.859895,NO,128,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.922,-4.314,2.392,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.100394,0.00774689,0.859895 kka2_1:8_P128Q,kka2_1:8_128,Kka2,kka2_1:8,P00552,0.859895,NO,128,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.922,-4.314,2.392,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.100394,0.00774689,0.859895 beta-lactamase_N168D,beta-lactamase_168,TEM-1,beta-lactamase,P62593,0.859958,NO,168,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-1.029,-3.143,2.114,5.42128,0.113,G,A,0.09,-0.4,1.211,,44.41,HPA,-1.13233,0.221079,0.00288667,0.859958 kka2_1:4_A119T,kka2_1:4_119,Kka2,kka2_1:4,P00552,0.859977,NO,119,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.073,-3.309,2.236,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.168804,0.00441074,0.859977 kka2_1:8_Y244F,kka2_1:8_244,Kka2,kka2_1:8,P00552,0.860021,NO,244,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-0.775,-2.97,2.195,,0.066,H,A,1.25,-0.64,,,,HHO,-1.41267,0.100394,0.00453187,0.860021 kka2_1:8_Y244F,kka2_1:8_244,Kka2,kka2_1:8,P00552,0.860021,NO,244,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-0.775,-2.97,2.195,,0.066,H,A,1.25,-0.64,,,,HHO,-1.41267,0.100394,0.00453187,0.860021 beta-lactamase_L10W,beta-lactamase_10,TEM-1,beta-lactamase,P62593,0.860066,NO,10,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.623,-5.136,3.513,,,,,,,2.467,,65.38,HHH,-1.83833,0.221079,0.00296968,0.860066 beta-lactamase_G216E,beta-lactamase_216,TEM-1,beta-lactamase,P62593,0.860127,NO,216,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.477,-2.451,0.974,4.91694,0.437,I,A,0.23,-0.58,1.718,,74.48,HOO,-1.68067,0.221079,0.00639568,0.860127 PSD95pdz3_F337A,PSD95pdz3_337,PSD95pdz3,PSD95pdz3,P31016,0.860137,NO,337,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.524,-2.984,1.46,5.22838,,,,,13.4936,,,,HHH,-1.59467,0.0758425,0.000875287,0.860137 PSD95pdz3_V362L,PSD95pdz3_362,PSD95pdz3,PSD95pdz3,P31016,0.860168,NO,362,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.465,-2.365,0.9,4.99436,,,,,19.6443,,,,PHP,-1.46467,0.0758425,0.000538527,0.860168 beta-lactamase_A34G,beta-lactamase_34,TEM-1,beta-lactamase,P62593,0.860172,NO,34,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.059,-3.469,1.41,4.9129,,H,A,0.75,-0.54,3.614,,73.78,AHA,-1.74967,0.221079,0.00407913,0.860172 kka2_1:2_E161G,kka2_1:2_161,Kka2,kka2_1:2,P00552,0.860183,NO,161,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.581,-3.389,1.808,,0.829,G,A,1.52,2.24,1.612,,92.05,AAB,-1.861,0.295029,0.00760103,0.860183 kka2_1:1_A71E,kka2_1:1_71,Kka2,kka2_1:1,P00552,0.860228,NO,71,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.824,-2.798,0.974,,0.553,H,A,0.46,0.08,9.788,,64.39,HHP,-1.74033,0.520039,0.00727707,0.860228 beta-lactamase_M1L,beta-lactamase_1,TEM-1,beta-lactamase,P62593,0.860232,NO,1,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.998,-2.14,0.142,,,,,,,,,,OHP,-1.97,0.221079,0.00162771,0.860232 beta-lactamase_0_K109I,beta-lactamase_0_109,TEM-1,beta-lactamase_0,P62593,0.860239,NO,109,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.734,-4.102,2.368,,0.787,G,A,2.34,2.21,15.473,15.473,72.73,ABB,-1.63333,0.0500837,0.00462493,0.860239 beta-lactamase_L89I,beta-lactamase_89,TEM-1,beta-lactamase,P62593,0.860256,NO,89,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.096,-3.166,2.07,5.41092,0.168,T,A,1.75,0.63,1.599,,64.34,PHO,-1.75767,0.221079,0.00207068,0.860256 beta-lactamase_0_L192Y,beta-lactamase_0_192,TEM-1,beta-lactamase_0,P62593,0.860286,NO,192,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.254,-3.913,2.659,,0.095,H,A,0.55,0.35,1.756,,60.14,HHP,-1.41833,0.0500837,0.00558728,0.860286 beta-lactamase_S240Q,beta-lactamase_240,TEM-1,beta-lactamase,P62593,0.860287,NO,240,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.537,-3.924,2.387,4.75024,,,B,0.74,-0.74,0.357,,65.38,OPB,-1.263,0.221079,0.00591201,0.860287 beta-lactamase_A123V,beta-lactamase_123,TEM-1,beta-lactamase,P62593,0.860301,NO,123,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.834,-2.392,1.558,4.70061,0.039,H,A,0.52,-0.72,0.705,,41.26,PHH,-1.47367,0.221079,0.0010157,0.860301 beta-lactamase_0_S57I,beta-lactamase_0_57,TEM-1,beta-lactamase_0,P62593,0.860309,NO,57,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.918,-3.825,1.907,,0.352,E,B,0.27,-0.18,1.454,,72.73,APH,-2.29167,0.0500837,0.00492804,0.860309 beta-lactamase_2500_R118I,beta-lactamase_2500_118,TEM-1,beta-lactamase_2500,P62593,0.860309,NO,118,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.413,-3.968,1.555,,0.457,H,A,1.2,1.39,2.144,,77.62,HBA,-1.785,0.361275,0.00538794,0.860309 Pab1_A185R,Pab1_185,Pab1,Pab1,P04147,0.860317,NO,185,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.702,-3.604,1.902,,,,,,,1.756,,63.26,AHH,-1.66167,0.175299,0.00144499,0.860317 beta-lactamase_0_K32C,beta-lactamase_0_32,TEM-1,beta-lactamase_0,P62593,0.860403,NO,32,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.984,-5.093,3.109,,0.563,H,A,2.34,0.34,0.418,,73.08,HBA,-2.04233,0.0500837,0.00401283,0.860403 beta-lactamase_0_T178W,beta-lactamase_0_178,TEM-1,beta-lactamase_0,P62593,0.860432,NO,178,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-0.791,-5.097,4.306,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.0500837,0.000684366,0.860432 kka2_1:1_A41S,kka2_1:1_41,Kka2,kka2_1:1,P00552,0.860451,NO,41,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.879,-2.842,0.963,,0.184,.,B,0.46,-0.96,18.207,18.207,64.39,PHP,-2.477,0.520039,0.00543332,0.860451 beta-lactamase_0_W288F,beta-lactamase_0_288,TEM-1,beta-lactamase_0,P62593,0.860462,NO,288,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,,,,,,,,,,,,,BHO,,0.0500837,,0.860462 beta-lactamase_F22I,beta-lactamase_22,TEM-1,beta-lactamase,P62593,0.8605,NO,22,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-2.676,-2.844,0.168,,,,,,,1.616,,73.08,HHH,-2.03233,0.221079,0.00262842,0.8605 beta-lactamase_0_S266K,beta-lactamase_0_266,TEM-1,beta-lactamase_0,P62593,0.860537,NO,266,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.0500837,0.0140785,0.860537 kka2_1:2_D52L,kka2_1:2_52,Kka2,kka2_1:2,P00552,0.86055,NO,52,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.271,-3.655,1.384,,0.22,E,B,0.75,0.8,1.123,,71.59,PAH,-2.38367,0.295029,0.00175694,0.86055 beta-lactamase_G236S,beta-lactamase_236,TEM-1,beta-lactamase,P62593,0.860561,NO,236,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.784,-2.475,1.691,4.7915,0.241,,b,0.23,-0.59,1.883,,64.69,HOA,-1.36933,0.221079,0.00162372,0.860561 beta-lactamase_V106R,beta-lactamase_106,TEM-1,beta-lactamase,P62593,0.860609,NO,106,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.218,-4.201,2.983,5.23115,0.258,T,A,0.96,0.24,1.188,,72.73,OHP,-1.04933,0.221079,0.00304168,0.860609 beta-lactamase_0_A124N,beta-lactamase_0_124,TEM-1,beta-lactamase_0,P62593,0.860648,NO,124,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.181,-3.812,2.631,,,H,A,0.46,-0.9,1.876,,64.34,HHH,-1.152,0.0500837,0.00481399,0.860648 PSD95pdz3_E373S,PSD95pdz3_373,PSD95pdz3,PSD95pdz3,P31016,0.860685,NO,373,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.404,-2.842,1.438,5.79743,,,,,27.9833,,,,BAP,-1.57667,0.0758425,0.000387698,0.860685 beta-lactamase_G141K,beta-lactamase_141,TEM-1,beta-lactamase,P62593,0.860705,NO,141,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.828,-3.62,2.792,5.03155,0.575,T,l,0.76,-0.28,0.198,,64.69,HOO,-1.08933,0.221079,0.0012419,0.860705 beta-lactamase_Q204F,beta-lactamase_204,TEM-1,beta-lactamase,P62593,0.860705,NO,204,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-1.382,-4.303,2.921,5.46394,0.204,H,A,0.12,0.09,1.707,,66.08,PPH,-1.49067,0.221079,0.00364106,0.860705 beta-lactamase_S201K,beta-lactamase_201,TEM-1,beta-lactamase,P62593,0.860705,NO,201,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.183,-3.387,2.204,4.85496,0.064,H,A,0.77,-0.07,4.045,,64.69,HPB,-1.451,0.221079,0.00198815,0.860705 kka2_1:1_A168R,kka2_1:1_168,Kka2,kka2_1:1,P00552,0.860712,NO,168,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.989,-3.003,1.014,,0.67,H,A,0.46,0.15,25.546,25.546,64.39,OHA,-2.12933,0.520039,0.00806773,0.860712 PSD95pdz3_G345D,PSD95pdz3_345,PSD95pdz3,PSD95pdz3,P31016,0.860716,NO,345,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.008,-3.15,2.142,4.32868,,,,,13.165,,,,OOO,-1.084,0.0758425,0.000771806,0.860716 beta-lactamase_156_N134F,beta-lactamase_156_134,TEM-1,beta-lactamase_156,P62593,0.860866,NO,134,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-0.879,-4.318,3.439,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.111618,0.000644786,0.860866 beta-lactamase_0_D177I,beta-lactamase_0_177,TEM-1,beta-lactamase_0,P62593,0.860923,NO,177,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.967,-4.048,3.081,,0.006,T,L,0.75,-1.02,3.536,,64.69,BAP,-0.873667,0.0500837,0.000864022,0.860923 PSD95pdz3_E373L,PSD95pdz3_373,PSD95pdz3,PSD95pdz3,P31016,0.861003,NO,373,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.404,-3.265,1.861,5.79743,,,,,27.9833,,,,BAP,-1.57667,0.0758425,0.000387698,0.861003 beta-lactamase_0_L218K,beta-lactamase_0_218,TEM-1,beta-lactamase_0,P62593,0.861018,NO,218,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.391,-2.186,0.795,,,I,b,0.55,-0.53,28.707,28.707,74.48,OHH,-1.58867,0.0500837,0.00618274,0.861018 kka2_1:2_A166G,kka2_1:2_166,Kka2,kka2_1:2,P00552,0.861027,NO,166,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.407,-2.83,0.423,,0.534,.,B,0.46,1.03,23.175,23.175,71.59,HHO,-2.421,0.295029,0.00799912,0.861027 beta-lactamase_0_K286P,beta-lactamase_0_286,TEM-1,beta-lactamase_0,P62593,0.861036,NO,286,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.0500837,,0.861036 beta-lactamase_L89A,beta-lactamase_89,TEM-1,beta-lactamase,P62593,0.861122,NO,89,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.096,-2.465,1.369,5.41092,0.168,T,A,1.75,0.63,1.599,,64.34,PHO,-1.75767,0.221079,0.00207068,0.861122 beta-lactamase_0_S128P,beta-lactamase_0_128,TEM-1,beta-lactamase_0,P62593,0.861164,NO,128,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-0.84,-3.655,2.815,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.0500837,0.00071483,0.861164 E1_Ubiquitin_G47P,E1_Ubiquitin_47,Uba1,E1_Ubiquitin,P0CG63,0.861185,NO,47,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.999,-3.69,2.691,,0.057,T,l,,-1.21,,,,HOB,-1.195,0.18783,0.00142261,0.861185 beta-lactamase_156_L74S,beta-lactamase_156_74,TEM-1,beta-lactamase_156,P62593,0.861187,NO,74,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.296,-3.399,2.103,,,H,A,0.55,-0.91,0.746,,50,HHO,-1.34933,0.111618,0.00493255,0.861187 kka2_1:2_L57A,kka2_1:2_57,Kka2,kka2_1:2,P00552,0.861195,NO,57,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.898,-3.394,1.496,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.295029,0.00723769,0.861195 Pab1_S155H,Pab1_155,Pab1,Pab1,P04147,0.861218,NO,155,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.039,-4.695,2.656,,,,,,,,,,PPB,-1.42267,0.175299,0.00208179,0.861218 beta-lactamase_0_L167P,beta-lactamase_0_167,TEM-1,beta-lactamase_0,P62593,0.861254,NO,167,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.138,-4.076,2.938,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.0500837,0.00303566,0.861254 beta-lactamase_G279T,beta-lactamase_279,TEM-1,beta-lactamase,P62593,0.861276,NO,279,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.038,-2.613,1.575,4.53882,,H,A,0.46,-0.97,3.066,,62.59,HOH,-1.36467,0.221079,0.0192826,0.861276 beta-lactamase_0_L47V,beta-lactamase_0_47,TEM-1,beta-lactamase_0,P62593,0.861305,NO,47,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.876,-2.564,0.688,,0.007,E,B,0.55,0.2,1.024,,67.83,AHA,-1.639,0.0500837,0.00439844,0.861305 kka2_1:8_G181P,kka2_1:8_181,Kka2,kka2_1:8,P00552,0.861377,NO,181,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-2.698,-3.097,0.399,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.100394,0.00728319,0.861377 kka2_1:8_G181P,kka2_1:8_181,Kka2,kka2_1:8,P00552,0.861377,NO,181,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-2.698,-3.097,0.399,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.100394,0.00728319,0.861377 beta-lactamase_2500_I206E,beta-lactamase_2500_206,TEM-1,beta-lactamase_2500,P62593,0.861449,NO,206,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-2.429,-2.747,0.318,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.361275,0.00528934,0.861449 Pab1_F146W,Pab1_146,Pab1,Pab1,P04147,0.861452,NO,146,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.149,-4.24,3.091,,0.006,H,A,,0.75,,,,PHP,-1.161,0.175299,0.000329265,0.861452 beta-lactamase_0_G154M,beta-lactamase_0_154,TEM-1,beta-lactamase_0,P62593,0.861505,NO,154,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.823,-4.936,4.113,,0.54,T,l,0.29,-0.56,3.629,,64.69,HOA,-1.635,0.0500837,0.00180205,0.861505 beta-lactamase_156_G236E,beta-lactamase_156_236,TEM-1,beta-lactamase_156,P62593,0.86152,NO,236,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.784,-3.634,2.85,,0.241,,b,0.29,-0.59,1.883,,64.69,HOO,-1.025,0.111618,0.00162372,0.86152 gb1_G264R,gb1_264,gb1,gb1,P06654,0.861555,NO,264,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.833,-3.738,1.905,,,,,,,0.864,,44.87,POH,-1.61267,0.177985,0.0049716,0.861555 gb1_T242P,gb1_242,gb1,gb1,P06654,0.861555,NO,242,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.245,-3.39,2.145,,,,,,,,,,APP,-1.444,0.177985,0.00243886,0.861555 kka2_1:4_S105M,kka2_1:4_105,Kka2,kka2_1:4,P00552,0.861565,NO,105,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.945,-4.741,2.796,,0.056,S,B,0.77,-1.04,3.442,,65.53,PPB,-2.17033,0.168804,0.00847233,0.861565 beta-lactamase_0_P25S,beta-lactamase_0_25,TEM-1,beta-lactamase_0,P62593,0.861624,NO,25,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.526,-3.274,1.748,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.0500837,0.00347571,0.861624 beta-lactamase_0_F64N,beta-lactamase_0_64,TEM-1,beta-lactamase_0,P62593,0.861629,NO,64,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-0.841,-4.123,3.282,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.0500837,0.000947691,0.861629 beta-lactamase_0_R92E,beta-lactamase_0_92,TEM-1,beta-lactamase_0,P62593,0.861634,NO,92,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.718,-2.624,0.906,,0.479,E,B,1.2,1.36,2.331,,65.38,BBH,-1.50367,0.0500837,0.00429626,0.861634 kka2_1:8_G43I,kka2_1:8_43,Kka2,kka2_1:8,P00552,0.861652,NO,43,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.587,-4.201,2.614,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.100394,0.0071925,0.861652 kka2_1:8_G43I,kka2_1:8_43,Kka2,kka2_1:8,P00552,0.861652,NO,43,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.587,-4.201,2.614,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.100394,0.0071925,0.861652 kka2_1:8_Q27K,kka2_1:8_27,Kka2,kka2_1:8,P00552,0.861677,NO,27,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-1.659,-3.492,1.833,,0.608,.,A,0.64,0.71,3.919,,65.53,PPP,-1.90733,0.100394,0.00595365,0.861677 kka2_1:8_Q27K,kka2_1:8_27,Kka2,kka2_1:8,P00552,0.861677,NO,27,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-1.659,-3.492,1.833,,0.608,.,A,0.64,0.71,3.919,,65.53,PPP,-1.90733,0.100394,0.00595365,0.861677 PSD95pdz3_L342W,PSD95pdz3_342,PSD95pdz3,PSD95pdz3,P31016,0.861682,NO,342,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.347,-4.779,3.432,5.03015,,,,,12.0762,,,,HHH,-1.428,0.0758425,0.00081112,0.861682 kka2_1:2_Q100H,kka2_1:2_100,Kka2,kka2_1:2,P00552,0.86169,NO,100,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.77,-2.906,0.136,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.295029,0.0066405,0.86169 beta-lactamase_625_G52R,beta-lactamase_625_52,TEM-1,beta-lactamase_625,P62593,0.86172,NO,52,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.149,-3.956,2.807,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.213352,0.00340138,0.86172 beta-lactamase_F228S,beta-lactamase_228,TEM-1,beta-lactamase,P62593,0.861758,NO,228,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-2.342,-3.492,1.15,5.33448,0.154,E,B,1.1,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.221079,0.0046669,0.861758 kka2_1:4_D250T,kka2_1:4_250,Kka2,kka2_1:4,P00552,0.861758,NO,250,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.015,-3.493,2.478,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.168804,0.0177103,0.861758 beta-lactamase_625_A40W,beta-lactamase_625_40,TEM-1,beta-lactamase_625,P62593,0.86179,NO,40,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.402,-5.298,3.896,,0.155,S,B,0.46,0.21,1.357,,73.78,OHB,-1.40267,0.213352,0.00490026,0.86179 beta-lactamase_Q203W,beta-lactamase_203,TEM-1,beta-lactamase,P62593,0.86179,NO,203,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.168,-5.466,3.298,5.65296,0.47,H,A,0.12,-0.38,1.66,,65.38,BPP,-1.614,0.221079,0.00631514,0.86179 beta-lactamase_156_R220Y,beta-lactamase_156_220,TEM-1,beta-lactamase_156,P62593,0.861799,NO,220,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-0.942,-4.188,3.246,,0.295,I,A,1.2,-0.76,2.164,,74.48,HBP,-1.33633,0.111618,0.00232421,0.861799 PSD95pdz3_E331A,PSD95pdz3_331,PSD95pdz3,PSD95pdz3,P31016,0.861863,NO,331,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.404,-2.759,1.355,5.86289,,,,,51.8889,,,,OAA,-1.22533,0.0758425,0.000950134,0.861863 kka2_1:4_D227A,kka2_1:4_227,Kka2,kka2_1:4,P00552,0.861867,NO,227,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.758,-2.851,1.093,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.168804,0.00745029,0.861867 beta-lactamase_H285D,beta-lactamase_285,TEM-1,beta-lactamase,P62593,0.861871,NO,285,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-1.845,-3.331,1.486,5.64289,0.312,T,a,0.35,0.64,1.401,,72.73,BBH,-1.64567,0.221079,0.101555,0.861871 kka2_1:4_D82A,kka2_1:4_82,Kka2,kka2_1:4,P00552,0.861885,NO,82,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.946,-1.898,-0.048,,0.341,E,b,0.75,0.52,11.923,11.923,63.64,HAH,-1.98,0.168804,0.00637516,0.861885 gb1_G264K,gb1_264,gb1,gb1,P06654,0.861935,NO,264,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.833,-3.487,1.654,,,,,,,0.864,,44.87,POH,-1.61267,0.177985,0.0049716,0.861935 kka2_1:1_L53M,kka2_1:1_53,Kka2,kka2_1:1,P00552,0.861943,NO,53,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-2.681,-3.617,0.936,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.520039,0.00671168,0.861943 beta-lactamase_2500_P255G,beta-lactamase_2500_255,TEM-1,beta-lactamase_2500,P62593,0.862003,NO,255,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.361275,0.00499612,0.862003 beta-lactamase_T158F,beta-lactamase_158,TEM-1,beta-lactamase,P62593,0.862029,NO,158,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.116,-4.177,3.061,5.32011,0.036,,B,0.98,-0.85,2.755,,69.58,HPB,-1.269,0.221079,0.00341825,0.862029 beta-lactamase_0_E35M,beta-lactamase_0_35,TEM-1,beta-lactamase_0,P62593,0.862032,NO,35,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-0.869,-4.754,3.885,,0.15,H,A,1.04,0.21,0.664,,46.85,HAA,-1.88667,0.0500837,0.00174441,0.862032 beta-lactamase_2500_N274T,beta-lactamase_2500_274,TEM-1,beta-lactamase_2500,P62593,0.862146,NO,274,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.361275,0.0110418,0.862146 beta-lactamase_0_A133W,beta-lactamase_0_133,TEM-1,beta-lactamase_0,P62593,0.86216,NO,133,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.186,-5.303,4.117,,,H,A,0.46,-0.86,2.148,,67.83,HHP,-0.988333,0.0500837,0.00468022,0.86216 kka2_1:2_L19M,kka2_1:2_19,Kka2,kka2_1:2,P00552,0.862185,NO,19,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.254,-4.18,2.926,,0.08,T,A,0.55,-0.26,17.165,17.165,65.53,BHH,-2.221,0.295029,0.00620703,0.862185 Pab1_D138I,Pab1_138,Pab1,Pab1,P04147,0.862224,NO,138,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.128,-3.881,2.753,,0.427,,B,,-0.03,,,,HAP,-1.13967,0.175299,0.000567877,0.862224 beta-lactamase_A23P,beta-lactamase_23,TEM-1,beta-lactamase,P62593,0.862256,NO,23,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.548,-3.865,2.317,,,,,,,0.801,,93.01,HHB,-2.235,0.221079,0.00245563,0.862256 kka2_1:8_R258T,kka2_1:8_258,Kka2,kka2_1:8,P00552,0.862277,NO,258,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.626,-2.894,1.268,,0.316,H,A,0.16,-0.85,5.58,,53.03,HBH,-1.25933,0.100394,0.00983174,0.862277 kka2_1:8_R258T,kka2_1:8_258,Kka2,kka2_1:8,P00552,0.862277,NO,258,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.626,-2.894,1.268,,0.316,H,A,0.16,-0.85,5.58,,53.03,HBH,-1.25933,0.100394,0.00983174,0.862277 kka2_1:2_H139T,kka2_1:2_139,Kka2,kka2_1:2,P00552,0.862281,NO,139,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-2.809,-2.706,-0.103,,0.471,H,A,0.87,0.68,13.912,13.912,63.64,BBB,-2.22,0.295029,0.00734779,0.862281 beta-lactamase_2500_H287A,beta-lactamase_2500_287,TEM-1,beta-lactamase_2500,P62593,0.8623,NO,287,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,,,,,,,,,,,,,BBH,-1.111,0.361275,,0.8623 beta-lactamase_0_S57P,beta-lactamase_0_57,TEM-1,beta-lactamase_0,P62593,0.862341,NO,57,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.918,-3.952,2.034,,0.352,E,B,0.27,-0.18,1.454,,72.73,APH,-2.29167,0.0500837,0.00492804,0.862341 beta-lactamase_625_R242G,beta-lactamase_625_242,TEM-1,beta-lactamase_625,P62593,0.862363,NO,242,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.319,-3.802,2.483,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.213352,0.00452879,0.862363 beta-lactamase_K30N,beta-lactamase_30,TEM-1,beta-lactamase,P62593,0.862384,NO,30,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-2.307,-2.865,0.558,5.30605,0.142,H,A,1.82,-0.65,2.434,,93.01,HBH,-2.32833,0.221079,0.00448593,0.862384 beta-lactamase_0_A200H,beta-lactamase_0_200,TEM-1,beta-lactamase_0,P62593,0.862389,NO,200,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.878,-4.732,2.854,,0.757,H,A,0.46,-0.19,16.368,16.368,77.62,HHP,-2.001,0.0500837,0.0060056,0.862389 beta-lactamase_625_G52Y,beta-lactamase_625_52,TEM-1,beta-lactamase_625,P62593,0.862392,NO,52,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.149,-4.436,3.287,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.213352,0.00340138,0.862392 beta-lactamase_0_G234R,beta-lactamase_0_234,TEM-1,beta-lactamase_0,P62593,0.862404,NO,234,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.62,-3.933,3.313,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.0500837,0.000889577,0.862404 beta-lactamase_0_T198V,beta-lactamase_0_198,TEM-1,beta-lactamase_0,P62593,0.862419,NO,198,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.168,-2.827,0.659,,0.489,,B,0.22,-0.13,9.874,,73.78,HPH,-1.98767,0.0500837,0.004311,0.862419 beta-lactamase_F228R,beta-lactamase_228,TEM-1,beta-lactamase,P62593,0.862435,NO,228,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-2.342,-2.044,-0.298,5.33448,0.154,E,B,1.1,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.221079,0.0046669,0.862435 kka2_1:2_G151K,kka2_1:2_151,Kka2,kka2_1:2,P00552,0.862473,NO,151,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.873,-3.594,2.721,,0.678,T,l,0.29,1.36,1.357,,49.62,HOH,-1.11433,0.295029,0.00339918,0.862473 beta-lactamase_2500_V214M,beta-lactamase_2500_214,TEM-1,beta-lactamase_2500,P62593,0.862484,NO,214,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.299,-4.251,2.952,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.361275,0.00628442,0.862484 Pab1_V148P,Pab1_148,Pab1,Pab1,P04147,0.862485,NO,148,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.875,-3.691,1.816,,,,,,,,,,PHH,-1.43033,0.175299,0.00179641,0.862485 beta-lactamase_R176E,beta-lactamase_176,TEM-1,beta-lactamase,P62593,0.862514,NO,176,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-0.863,-3.215,2.352,5.61264,0.385,T,B,0.68,-0.63,,,,ABA,-1.38867,0.221079,0.00105554,0.862514 beta-lactamase_0_R257D,beta-lactamase_0_257,TEM-1,beta-lactamase_0,P62593,0.862535,NO,257,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.0500837,0.00756629,0.862535 kka2_1:2_H124N,kka2_1:2_124,Kka2,kka2_1:2,P00552,0.862594,NO,124,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-0.84,-3.251,2.411,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.295029,0.00211296,0.862594 kka2_1:2_S105T,kka2_1:2_105,Kka2,kka2_1:2,P00552,0.862606,NO,105,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.945,-2.444,0.499,,0.056,S,B,0.27,-1.04,3.442,,65.53,PPB,-2.17033,0.295029,0.00847233,0.862606 kka2_1:2_T73L,kka2_1:2_73,Kka2,kka2_1:2,P00552,0.862643,NO,73,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.51,-2.574,0.064,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.295029,0.00628605,0.862643 beta-lactamase_F17K,beta-lactamase_17,TEM-1,beta-lactamase,P62593,0.862679,NO,17,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-2.337,-3.702,1.365,,,,,,,2.192,,67.83,HHO,-2.17733,0.221079,0.00216499,0.862679 beta-lactamase_S240T,beta-lactamase_240,TEM-1,beta-lactamase,P62593,0.862702,NO,240,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.537,-1.74,0.203,4.75024,,,B,0.74,-0.74,0.357,,65.38,OPB,-1.263,0.221079,0.00591201,0.862702 kka2_1:8_Y257H,kka2_1:8_257,Kka2,kka2_1:8,P00552,0.862702,NO,257,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-1.064,-4.042,2.978,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.100394,0.0148191,0.862702 kka2_1:8_Y257H,kka2_1:8_257,Kka2,kka2_1:8,P00552,0.862702,NO,257,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-1.064,-4.042,2.978,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.100394,0.0148191,0.862702 beta-lactamase_F14G,beta-lactamase_14,TEM-1,beta-lactamase,P62593,0.862785,NO,14,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-2.736,-3.71,0.974,,,,,,,1.537,,93.01,HHH,-2.26133,0.221079,0.00277095,0.862785 beta-lactamase_156_R220C,beta-lactamase_156_220,TEM-1,beta-lactamase_156,P62593,0.862858,NO,220,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-0.942,-5.009,4.067,,0.295,I,A,1.2,-0.76,2.164,,74.48,HBP,-1.33633,0.111618,0.00232421,0.862858 beta-lactamase_L38H,beta-lactamase_38,TEM-1,beta-lactamase,P62593,0.862876,NO,38,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.343,-3.182,1.839,5.23728,0.088,H,A,1.75,0.2,1.986,,64.34,PHO,-1.78033,0.221079,0.00373244,0.862876 kka2_1:8_A119G,kka2_1:8_119,Kka2,kka2_1:8,P00552,0.862877,NO,119,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.073,-2.216,1.143,,0.019,H,A,0.46,-0.57,1.511,,71.59,AHH,-2.34,0.100394,0.00441074,0.862877 kka2_1:8_A119G,kka2_1:8_119,Kka2,kka2_1:8,P00552,0.862877,NO,119,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.073,-2.216,1.143,,0.019,H,A,0.46,-0.57,1.511,,71.59,AHH,-2.34,0.100394,0.00441074,0.862877 Ubiquitin_E51Y,Ubiquitin_51,Uba1,Ubiquitin,P0CG48,0.862903,NO,51,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.534,-4.307,2.773,5.36711,0.545,,B,,0.72,,,,HAA,-1.357,0.205827,0.000868134,0.862903 Ubiquitin_G35K,Ubiquitin_35,Uba1,Ubiquitin,P0CG48,0.862903,NO,35,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.171,-3.58,2.409,4.96213,0.713,,L,,0.2,,,,AOH,-1.314,0.205827,0.000648878,0.862903 Ubiquitin_G35R,Ubiquitin_35,Uba1,Ubiquitin,P0CG48,0.862903,NO,35,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.171,-3.917,2.746,4.96213,0.713,,L,,0.2,,,,AOH,-1.314,0.205827,0.000648878,0.862903 Ubiquitin_I36C,Ubiquitin_36,Uba1,Ubiquitin,P0CG48,0.862903,NO,36,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.477,-4.746,3.269,5.1035,0.203,,B,0.27,-0.22,1.552,,30.8,OHO,-1.30767,0.205827,0.000630555,0.862903 Ubiquitin_K27A,Ubiquitin_27,Uba1,Ubiquitin,P0CG48,0.862903,NO,27,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.064,-3.046,1.982,4.77438,0.086,H,A,2.89,-0.74,2.662,,27.01,HBH,-1.42667,0.205827,0.000767556,0.862903 Ubiquitin_K27C,Ubiquitin_27,Uba1,Ubiquitin,P0CG48,0.862903,NO,27,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.064,-5.087,4.023,4.77438,0.086,H,A,2.89,-0.74,2.662,,27.01,HBH,-1.42667,0.205827,0.000767556,0.862903 Ubiquitin_L67T,Ubiquitin_67,Uba1,Ubiquitin,P0CG48,0.862903,NO,67,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.435,-2.758,1.323,4.92156,,E,B,1.19,-1.02,6.371,6.371,30.8,PHB,-1.628,0.205827,0.000482727,0.862903 Ubiquitin_L8V,Ubiquitin_8,Uba1,Ubiquitin,P0CG48,0.862903,NO,8,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.723,-2.648,0.925,5.28016,0.664,T,A,0.08,-0.34,0.664,,29.05,PHP,-1.51567,0.205827,0.000726165,0.862903 Ubiquitin_Q40M,Ubiquitin_40,Uba1,Ubiquitin,P0CG48,0.862903,NO,40,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-1.752,-4.587,2.835,4.7807,0.387,G,A,,0.03,,,,APP,-1.62433,0.205827,0.000619089,0.862903 Ubiquitin_T14I,Ubiquitin_14,Uba1,Ubiquitin,P0CG48,0.862903,NO,14,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.598,-2.881,1.283,5.10811,0.345,E,B,,-0.37,,,,HPH,-1.41133,0.205827,0.000632754,0.862903 Ubiquitin_T14P,Ubiquitin_14,Uba1,Ubiquitin,P0CG48,0.862903,NO,14,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.598,-2.851,1.253,5.10811,0.345,E,B,,-0.37,,,,HPH,-1.41133,0.205827,0.000632754,0.862903 beta-lactamase_625_R257L,beta-lactamase_625_257,TEM-1,beta-lactamase_625,P62593,0.862909,NO,257,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.213352,0.00756629,0.862909 beta-lactamase_0_G265L,beta-lactamase_0_265,TEM-1,beta-lactamase_0,P62593,0.862916,NO,265,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.0500837,0.00811926,0.862916 beta-lactamase_156_E195I,beta-lactamase_156_195,TEM-1,beta-lactamase_156,P62593,0.862923,NO,195,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.186,-4.191,2.005,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.111618,0.00496565,0.862923 beta-lactamase_2500_F58L,beta-lactamase_2500_58,TEM-1,beta-lactamase_2500,P62593,0.862964,NO,58,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-2.914,-3.474,0.56,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.361275,0.00523369,0.862964 beta-lactamase_T126K,beta-lactamase_126,TEM-1,beta-lactamase,P62593,0.862991,NO,126,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.122,-3.536,2.414,4.82694,0.05,H,A,0.3,-0.05,1.14,,44.41,HPH,-1.60467,0.221079,0.00244552,0.862991 PSD95pdz3_F337N,PSD95pdz3_337,PSD95pdz3,PSD95pdz3,P31016,0.863034,NO,337,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.524,-3.805,2.281,5.22838,,,,,13.4936,,,,HHH,-1.59467,0.0758425,0.000875287,0.863034 beta-lactamase_625_M115R,beta-lactamase_625_115,TEM-1,beta-lactamase_625,P62593,0.863036,NO,115,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.389,-2.862,1.473,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.213352,0.0034337,0.863036 kka2_1:4_P128F,kka2_1:4_128,Kka2,kka2_1:4,P00552,0.863064,NO,128,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.922,-4.049,2.127,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.168804,0.00774689,0.863064 beta-lactamase_F13P,beta-lactamase_13,TEM-1,beta-lactamase,P62593,0.863065,NO,13,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-2.394,-4.032,1.638,,,,,,,4.079,,77.62,OHH,-2.382,0.221079,0.0029078,0.863065 gb1_K254R,gb1_254,gb1,gb1,P06654,0.863069,NO,254,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.748,-3.105,1.357,,,,,,,1.793,,37.28,ABH,-2.195,0.177985,0.00622711,0.863069 beta-lactamase_0_A185P,beta-lactamase_0_185,TEM-1,beta-lactamase_0,P62593,0.863084,NO,185,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.406,-2.861,1.455,,,H,A,0.46,-1.02,1.203,,65.03,HHP,-1.84033,0.0500837,0.00467449,0.863084 beta-lactamase_0_E26K,beta-lactamase_0_26,TEM-1,beta-lactamase_0,P62593,0.863106,NO,26,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.454,-3.374,0.92,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.0500837,0.00297948,0.863106 beta-lactamase_M268P,beta-lactamase_268,TEM-1,beta-lactamase,P62593,0.863106,NO,268,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-2.023,-4.157,2.134,5.4797,0.471,H,A,0.09,0.3,1.071,,65.73,PHA,-2.16233,0.221079,0.0102525,0.863106 beta-lactamase_2500_G253C,beta-lactamase_2500_253,TEM-1,beta-lactamase_2500,P62593,0.863144,NO,253,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.361275,0.00786358,0.863144 beta-lactamase_0_L191D,beta-lactamase_0_191,TEM-1,beta-lactamase_0,P62593,0.863162,NO,191,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.087,-4.092,3.005,,,H,A,0.55,0.09,12.255,12.255,63.29,BHH,-1.445,0.0500837,0.00263549,0.863162 kka2_1:2_E142T,kka2_1:2_142,Kka2,kka2_1:2,P00552,0.863189,NO,142,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.221,-2.837,0.616,,0.471,H,A,1.52,0.85,3.693,,65.53,HAB,-2.08033,0.295029,0.00748883,0.863189 beta-lactamase_F228V,beta-lactamase_228,TEM-1,beta-lactamase,P62593,0.86321,NO,228,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-2.342,-2.889,0.547,5.33448,0.154,E,B,1.1,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.221079,0.0046669,0.86321 beta-lactamase_L74I,beta-lactamase_74,TEM-1,beta-lactamase,P62593,0.863246,NO,74,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.296,-2.577,1.281,5.50288,,H,A,1.75,-0.91,1.581,,50,HHO,-1.34933,0.221079,0.00493255,0.863246 beta-lactamase_2500_L137Y,beta-lactamase_2500_137,TEM-1,beta-lactamase_2500,P62593,0.863251,NO,137,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.03,-4.002,2.972,,,H,A,0.55,-0.38,0.769,,42.31,HHP,-1.58933,0.361275,0.00278599,0.863251 kka2_1:2_A64Y,kka2_1:2_64,Kka2,kka2_1:2,P00552,0.863273,NO,64,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.496,-4.253,2.757,,0.039,H,A,0.46,-0.57,14.509,14.509,56.06,AHH,-1.334,0.295029,0.00705578,0.863273 beta-lactamase_D99F,beta-lactamase_99,TEM-1,beta-lactamase,P62593,0.863305,NO,99,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.191,-4.277,3.086,5.66081,0.402,G,A,0.23,0.36,1.318,,64.69,PAH,-1.794,0.221079,0.00305446,0.863305 kka2_1:4_L60P,kka2_1:4_60,Kka2,kka2_1:4,P00552,0.863317,NO,60,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.997,-4.194,3.197,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.168804,0.00262176,0.863317 beta-lactamase_0_T147N,beta-lactamase_0_147,TEM-1,beta-lactamase_0,P62593,0.863352,NO,147,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.149,-2.415,1.266,,0.281,H,A,0.22,-0.68,3.487,,64.34,HPH,-1.456,0.0500837,0.00226017,0.863352 beta-lactamase_0_A247C,beta-lactamase_0_247,TEM-1,beta-lactamase_0,P62593,0.863359,NO,247,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.0500837,0.00611275,0.863359 beta-lactamase_156_P65L,beta-lactamase_156_65,TEM-1,beta-lactamase_156,P62593,0.863402,NO,65,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.894,-2.247,1.353,,0.098,E,B,0.52,-0.62,0.623,,40.56,HOH,-1.03233,0.111618,0.00152776,0.863402 beta-lactamase_0_T112D,beta-lactamase_0_112,TEM-1,beta-lactamase_0,P62593,0.863415,NO,112,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.186,-2.66,0.474,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.0500837,0.00531334,0.863415 beta-lactamase_39_G249Y,beta-lactamase_39_249,TEM-1,beta-lactamase_39,P62593,0.863419,NO,249,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.312,,,,0.256,S,B,0.23,0.04,30.841,30.841,72.73,HOO,-1.81367,0.0495842,0.00220169,0.863419 gb1_V280S,gb1_280,gb1,gb1,P06654,0.863446,NO,280,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.764,-3.168,1.404,,,,,,,0.874,,35.71,PHP,-1.63733,0.177985,0.00321577,0.863446 beta-lactamase_0_P224V,beta-lactamase_0_224,TEM-1,beta-lactamase_0,P62593,0.863451,NO,224,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.893,-3.599,2.706,,0.383,,B,0.52,-0.3,3.587,,74.48,HOH,-1.26433,0.0500837,0.00189564,0.863451 kka2_1:4_D261G,kka2_1:4_261,Kka2,kka2_1:4,P00552,0.863499,NO,261,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.708,-3.161,2.453,,0.146,G,A,0.75,-0.33,,,,HAA,-0.759333,0.168804,0.0224846,0.863499 beta-lactamase_625_A40L,beta-lactamase_625_40,TEM-1,beta-lactamase_625,P62593,0.863542,NO,40,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.402,-3.399,1.997,,0.155,S,B,0.46,0.21,1.357,,73.78,OHB,-1.40267,0.213352,0.00490026,0.863542 beta-lactamase_0_M115D,beta-lactamase_0_115,TEM-1,beta-lactamase_0,P62593,0.863598,NO,115,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.389,-4.023,2.634,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.0500837,0.0034337,0.863598 beta-lactamase_0_L73H,beta-lactamase_0_73,TEM-1,beta-lactamase_0,P62593,0.863605,NO,73,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.507,-4.923,3.416,,,H,A,0.55,-0.64,0.877,,67.83,HHH,-1.487,0.0500837,0.00488983,0.863605 beta-lactamase_0_G142S,beta-lactamase_0_142,TEM-1,beta-lactamase_0,P62593,0.863621,NO,142,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.707,-2.438,1.731,,0.034,,p,0.29,-0.64,1.947,,64.69,OOO,-0.834,0.0500837,0.00060149,0.863621 kka2_1:1_D238L,kka2_1:1_238,Kka2,kka2_1:1,P00552,0.86363,NO,238,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.83,-3.612,0.782,,0.604,H,A,0.75,-0.33,11.329,11.329,92.05,HAB,-2.633,0.520039,0.0113863,0.86363 beta-lactamase_2500_R162S,beta-lactamase_2500_162,TEM-1,beta-lactamase_2500,P62593,0.863673,NO,162,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.016,-3.456,2.44,,0.124,S,B,1.2,-0.37,6.199,,64.69,ABH,-1.25,0.361275,0.000561334,0.863673 beta-lactamase_0_I54E,beta-lactamase_0_54,TEM-1,beta-lactamase_0,P62593,0.863712,NO,54,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-2.838,-2.58,-0.258,,0.669,E,B,0.48,-0.14,0.541,,73.78,BHH,-2.337,0.0500837,0.00403589,0.863712 Pab1_A141H,Pab1_141,Pab1,Pab1,P04147,0.863712,NO,141,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.461,-4.563,3.102,,0.34,H,A,0.52,-0.27,2.15,,79.03,BHH,-1.19433,0.175299,0.00165974,0.863712 WW_domain_R187Q,WW_domain_187,Yap65,WW_domain,P46937,0.863718,NO,187,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.402,-3.289,1.887,5.05189,,,,,,3.431,,78.57,PBH,-1.362,0.153962,0.00171149,0.863718 kka2_1:4_G55C,kka2_1:4_55,Kka2,kka2_1:4,P00552,0.863803,NO,55,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.625,-5.134,3.509,,0.517,S,b,0.75,1.19,15.753,15.753,63.64,POH,-2.05967,0.168804,0.00667877,0.863803 PSD95pdz3_G345E,PSD95pdz3_345,PSD95pdz3,PSD95pdz3,P31016,0.863826,NO,345,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.008,-3.347,2.339,4.32868,,,,,13.165,,,,OOO,-1.084,0.0758425,0.000771806,0.863826 kka2_1:4_N200C,kka2_1:4_200,Kka2,kka2_1:4,P00552,0.863883,NO,200,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-2.446,-5.276,2.83,,0.756,T,L,0.61,-0.08,1.746,,64.39,APO,-2.08,0.168804,0.00838549,0.863883 beta-lactamase_39_D177A,beta-lactamase_39_177,TEM-1,beta-lactamase_39,P62593,0.863921,NO,177,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.967,-2.529,1.562,,0.006,T,L,0.75,-1.02,3.536,,64.69,BAP,-0.873667,0.0495842,0.000864022,0.863921 beta-lactamase_L111P,beta-lactamase_111,TEM-1,beta-lactamase,P62593,0.863928,NO,111,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.76,-4.076,2.316,5.8705,0.328,T,A,0.84,0.93,3.836,,64.34,BHP,-1.884,0.221079,0.00480671,0.863928 beta-lactamase_L38A,beta-lactamase_38,TEM-1,beta-lactamase,P62593,0.863948,NO,38,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.343,-3.151,1.808,5.23728,0.088,H,A,1.75,0.2,1.986,,64.34,PHO,-1.78033,0.221079,0.00373244,0.863948 beta-lactamase_0_Y262W,beta-lactamase_0_262,TEM-1,beta-lactamase_0,P62593,0.863953,NO,262,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.0500837,0.00853516,0.863953 beta-lactamase_0_A282W,beta-lactamase_0_282,TEM-1,beta-lactamase_0,P62593,0.863954,NO,282,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.0500837,0.0449821,0.863954 beta-lactamase_V214L,beta-lactamase_214,TEM-1,beta-lactamase,P62593,0.863956,NO,214,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.299,-2.237,0.938,5.74008,0.375,S,A,1.19,-0.44,1.899,,74.48,BHH,-1.53733,0.221079,0.00628442,0.863956 beta-lactamase_L89P,beta-lactamase_89,TEM-1,beta-lactamase,P62593,0.86396,NO,89,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.096,-2.221,1.125,5.41092,0.168,T,A,1.75,0.63,1.599,,64.34,PHO,-1.75767,0.221079,0.00207068,0.86396 beta-lactamase_0_Q37F,beta-lactamase_0_37,TEM-1,beta-lactamase_0,P62593,0.863976,NO,37,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.134,-4.314,2.18,,0.613,H,A,0.64,1.98,4.001,,73.08,APH,-2.06967,0.0500837,0.00425833,0.863976 beta-lactamase_D48H,beta-lactamase_48,TEM-1,beta-lactamase,P62593,0.864046,NO,48,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.101,-2.659,1.558,4.89966,0.189,E,B,0.23,0.21,1.281,,50.35,HAH,-1.62467,0.221079,0.0027273,0.864046 beta-lactamase_E62F,beta-lactamase_62,TEM-1,beta-lactamase,P62593,0.864046,NO,62,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.193,-4.376,3.183,5.93066,0.342,S,B,1.52,-0.3,3.139,,73.08,AAB,-1.417,0.221079,0.00264802,0.864046 beta-lactamase_L160N,beta-lactamase_160,TEM-1,beta-lactamase,P62593,0.864046,NO,160,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.977,-4.165,3.188,5.32068,0.022,,B,1.75,-0.6,0.895,,44.41,BHA,-0.936,0.221079,0.00193775,0.864046 beta-lactamase_R41D,beta-lactamase_41,TEM-1,beta-lactamase,P62593,0.864046,NO,41,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-0.942,-3.657,2.715,5.69185,0.321,E,B,0.91,-0.07,4.357,,65.03,HBH,-1.30267,0.221079,0.00123327,0.864046 beta-lactamase_V214I,beta-lactamase_214,TEM-1,beta-lactamase,P62593,0.864046,NO,214,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.299,-3.053,1.754,5.74008,0.375,S,A,1.19,-0.44,1.899,,74.48,BHH,-1.53733,0.221079,0.00628442,0.864046 beta-lactamase_0_L205S,beta-lactamase_0_205,TEM-1,beta-lactamase_0,P62593,0.864076,NO,205,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.922,-3.629,2.707,,,H,A,0.55,-0.46,1.065,,42.31,PHH,-1.57767,0.0500837,0.00255802,0.864076 PSD95pdz3_E373V,PSD95pdz3_373,PSD95pdz3,PSD95pdz3,P31016,0.864081,NO,373,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.404,-3.21,1.806,5.79743,,,,,27.9833,,,,BAP,-1.57667,0.0758425,0.000387698,0.864081 beta-lactamase_T267F,beta-lactamase_267,TEM-1,beta-lactamase,P62593,0.86411,NO,267,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.308,-4.356,2.048,5.28263,0.54,,B,0.69,-0.14,0.374,,73.78,HPH,-1.9,0.221079,0.0102128,0.86411 kka2_1:8_G30A,kka2_1:8_30,Kka2,kka2_1:8,P00552,0.864146,NO,30,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.596,-2.881,2.285,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.100394,0.00159208,0.864146 kka2_1:8_G30A,kka2_1:8_30,Kka2,kka2_1:8,P00552,0.864146,NO,30,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.596,-2.881,2.285,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.100394,0.00159208,0.864146 kka2_1:2_A64C,kka2_1:2_64,Kka2,kka2_1:2,P00552,0.864152,NO,64,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.496,-4.794,3.298,,0.039,H,A,0.46,-0.57,14.509,14.509,56.06,AHH,-1.334,0.295029,0.00705578,0.864152 kka2_1:8_L94S,kka2_1:8_94,Kka2,kka2_1:8,P00552,0.864196,NO,94,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.618,-3.596,1.978,,0.058,E,B,1.59,-0.52,2.197,,56.06,HHO,-1.612,0.100394,0.00520888,0.864196 kka2_1:8_L94S,kka2_1:8_94,Kka2,kka2_1:8,P00552,0.864196,NO,94,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.618,-3.596,1.978,,0.058,E,B,1.59,-0.52,2.197,,56.06,HHO,-1.612,0.100394,0.00520888,0.864196 beta-lactamase_0_H287V,beta-lactamase_0_287,TEM-1,beta-lactamase_0,P62593,0.864239,NO,287,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,,,,,,,,,,,,,BBH,-1.111,0.0500837,,0.864239 beta-lactamase_2500_V82T,beta-lactamase_2500_82,TEM-1,beta-lactamase_2500,P62593,0.864284,NO,82,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.325,-3.392,2.067,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.361275,0.00397046,0.864284 beta-lactamase_R189I,beta-lactamase_189,TEM-1,beta-lactamase,P62593,0.864291,NO,189,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.844,-4.147,2.303,5.74877,0.278,H,A,0.68,1.01,1.512,,72.73,HBB,-1.668,0.221079,0.0050699,0.864291 kka2_1:8_I196T,kka2_1:8_196,Kka2,kka2_1:8,P00552,0.86432,NO,196,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-2.115,-3.682,1.567,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.100394,0.0107273,0.86432 kka2_1:8_I196T,kka2_1:8_196,Kka2,kka2_1:8,P00552,0.86432,NO,196,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-2.115,-3.682,1.567,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.100394,0.0107273,0.86432 beta-lactamase_G154K,beta-lactamase_154,TEM-1,beta-lactamase,P62593,0.864324,NO,154,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.823,-3.683,2.86,5.40944,0.54,T,l,0.77,-0.56,2.283,,64.69,HOA,-1.635,0.221079,0.00180205,0.864324 beta-lactamase_I259F,beta-lactamase_259,TEM-1,beta-lactamase,P62593,0.864324,NO,259,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.522,-3.883,2.361,5.28457,,E,B,1,-0.8,1.24,,64.34,HHH,-1.53267,0.221079,0.0070773,0.864324 beta-lactamase_0_L137Y,beta-lactamase_0_137,TEM-1,beta-lactamase_0,P62593,0.864348,NO,137,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.03,-4.002,2.972,,,H,A,0.55,-0.38,0.328,,42.31,HHP,-1.58933,0.0500837,0.00278599,0.864348 kka2_1:2_S54R,kka2_1:2_54,Kka2,kka2_1:2,P00552,0.864409,NO,54,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.471,-2.798,0.327,,0.408,S,b,0.27,1.01,0.393,,71.59,HPO,-2.259,0.295029,0.00782867,0.864409 kka2_1:2_K175H,kka2_1:2_175,Kka2,kka2_1:2,P00552,0.864424,NO,175,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-2.897,-3.28,0.383,,0.579,H,A,1.3,0.51,15.629,15.629,71.59,HBH,-1.82333,0.295029,0.00693093,0.864424 beta-lactamase_F228C,beta-lactamase_228,TEM-1,beta-lactamase,P62593,0.864482,NO,228,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-2.342,-5.075,2.733,5.33448,0.154,E,B,1.1,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.221079,0.0046669,0.864482 gb1_L231S,gb1_231,gb1,gb1,P06654,0.86457,NO,231,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.603,-3.422,1.819,,,,,,,0.219,,11.83,BHH,-1.82633,0.177985,0.00322797,0.86457 kka2_1:8_R147F,kka2_1:8_147,Kka2,kka2_1:8,P00552,0.864593,NO,147,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.123,-4.324,3.201,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.100394,0.00549168,0.864593 kka2_1:8_R147F,kka2_1:8_147,Kka2,kka2_1:8,P00552,0.864593,NO,147,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.123,-4.324,3.201,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.100394,0.00549168,0.864593 beta-lactamase_0_L28D,beta-lactamase_0_28,TEM-1,beta-lactamase_0,P62593,0.864653,NO,28,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.579,-3.96,2.381,,0.277,H,A,0.55,-0.16,9.35,9.35,93.01,PHH,-2.11333,0.0500837,0.00359321,0.864653 beta-lactamase_D48N,beta-lactamase_48,TEM-1,beta-lactamase,P62593,0.864705,NO,48,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.101,-3.389,2.288,4.89966,0.189,E,B,0.23,0.21,1.281,,50.35,HAH,-1.62467,0.221079,0.0027273,0.864705 beta-lactamase_L89Y,beta-lactamase_89,TEM-1,beta-lactamase,P62593,0.864705,NO,89,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.096,-4.101,3.005,5.41092,0.168,T,A,1.75,0.63,1.599,,64.34,PHO,-1.75767,0.221079,0.00207068,0.864705 beta-lactamase_H110E,beta-lactamase_110,TEM-1,beta-lactamase,P62593,0.864745,NO,110,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-1.706,-2.766,1.06,5.52635,0.341,G,a,0.35,1.08,31.31,31.31,64.69,BBH,-1.73333,0.221079,0.00441499,0.864745 beta-lactamase_P253W,beta-lactamase_253,TEM-1,beta-lactamase,P62593,0.864745,NO,253,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-2.253,-5.519,3.266,5.24842,0.308,,B,0.73,-0.46,2.293,,73.08,BOP,-2.10633,0.221079,0.00786358,0.864745 kka2_1:4_R147Q,kka2_1:4_147,Kka2,kka2_1:4,P00552,0.864775,NO,147,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.123,-2.836,1.713,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.168804,0.00549168,0.864775 beta-lactamase_0_E195D,beta-lactamase_0_195,TEM-1,beta-lactamase_0,P62593,0.864783,NO,195,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.186,-1.979,-0.207,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.0500837,0.00496565,0.864783 beta-lactamase_I54K,beta-lactamase_54,TEM-1,beta-lactamase,P62593,0.864823,NO,54,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-2.838,-2.926,0.088,5.40541,0.669,E,B,0.77,-0.14,3.946,,73.78,BHH,-2.337,0.221079,0.00403589,0.864823 kka2_1:8_S104C,kka2_1:8_104,Kka2,kka2_1:8,P00552,0.864859,NO,104,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.436,-3.387,1.951,,0.536,T,A,0.27,-1.11,1.689,,63.64,HPP,-1.91433,0.100394,0.00555207,0.864859 kka2_1:8_S104C,kka2_1:8_104,Kka2,kka2_1:8,P00552,0.864859,NO,104,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.436,-3.387,1.951,,0.536,T,A,0.27,-1.11,1.689,,63.64,HPP,-1.91433,0.100394,0.00555207,0.864859 beta-lactamase_V21L,beta-lactamase_21,TEM-1,beta-lactamase,P62593,0.86486,NO,21,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.873,-2.366,0.493,,,,,,,0.688,,93.01,OHH,-2.09633,0.221079,0.0028612,0.86486 beta-lactamase_0_A124E,beta-lactamase_0_124,TEM-1,beta-lactamase_0,P62593,0.864919,NO,124,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.181,-3.544,2.363,,,H,A,0.46,-0.9,1.876,,64.34,HHH,-1.152,0.0500837,0.00481399,0.864919 kka2_1:4_G99K,kka2_1:4_99,Kka2,kka2_1:4,P00552,0.864933,NO,99,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.596,-3.71,3.114,,0.368,S,g,0.29,-0.87,,,,OOP,-1.63067,0.168804,0.00186055,0.864933 beta-lactamase_0_G243Q,beta-lactamase_0_243,TEM-1,beta-lactamase_0,P62593,0.864938,NO,243,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.0500837,0.00464034,0.864938 kka2_1:4_R38Q,kka2_1:4_38,Kka2,kka2_1:4,P00552,0.864971,NO,38,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.207,-3.749,2.542,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.168804,0.00372499,0.864971 beta-lactamase_0_A247K,beta-lactamase_0_247,TEM-1,beta-lactamase_0,P62593,0.865014,NO,247,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.0500837,0.00611275,0.865014 beta-lactamase_0_T107I,beta-lactamase_0_107,TEM-1,beta-lactamase_0,P62593,0.865022,NO,107,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.117,-3.664,2.547,,,G,A,0.22,-0.06,3.73,,67.83,HPA,-1.265,0.0500837,0.00239347,0.865022 beta-lactamase_L137T,beta-lactamase_137,TEM-1,beta-lactamase,P62593,0.865048,NO,137,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.03,-3.486,2.456,5.20117,,H,A,1.07,-0.38,0.674,,42.31,HHP,-1.58933,0.221079,0.00278599,0.865048 beta-lactamase_0_I125V,beta-lactamase_0_125,TEM-1,beta-lactamase_0,P62593,0.865057,NO,125,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.441,-2.101,0.66,,,H,A,0.48,-0.7,1.874,,63.29,HHP,-1.248,0.0500837,0.00383964,0.865057 beta-lactamase_0_L219F,beta-lactamase_0_219,TEM-1,beta-lactamase_0,P62593,0.865067,NO,219,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.313,-2.825,1.512,,,I,A,0.55,-0.51,6.513,6.513,74.48,HHB,-1.21533,0.0500837,0.00664345,0.865067 beta-lactamase_625_S266R,beta-lactamase_625_266,TEM-1,beta-lactamase_625,P62593,0.865122,NO,266,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.213352,0.0140785,0.865122 beta-lactamase_S104C,beta-lactamase_104,TEM-1,beta-lactamase,P62593,0.86517,NO,104,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.015,-2.945,1.93,4.92365,0.04,,b,0.82,0.57,4.02,,63.29,HPO,-1.05267,0.221079,0.00218083,0.86517 kka2_1:1_L60P,kka2_1:1_60,Kka2,kka2_1:1,P00552,0.865181,NO,60,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.997,-4.194,3.197,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.520039,0.00262176,0.865181 Pab1_V148W,Pab1_148,Pab1,Pab1,P04147,0.865182,NO,148,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.875,-5.23,3.355,,,,,,,,,,PHH,-1.43033,0.175299,0.00179641,0.865182 beta-lactamase_0_Q97H,beta-lactamase_0_97,TEM-1,beta-lactamase_0,P62593,0.865187,NO,97,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.072,-4.636,2.564,,0.823,G,A,0.64,2.42,16.954,16.954,77.62,PPP,-2.43833,0.0500837,0.0045116,0.865187 beta-lactamase_0_Q97S,beta-lactamase_0_97,TEM-1,beta-lactamase_0,P62593,0.865189,NO,97,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.072,-3.388,1.316,,0.823,G,A,0.64,2.42,16.954,16.954,77.62,PPP,-2.43833,0.0500837,0.0045116,0.865189 beta-lactamase_0_D252M,beta-lactamase_0_252,TEM-1,beta-lactamase_0,P62593,0.865205,NO,252,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.0500837,0.00575769,0.865205 beta-lactamase_2500_V259C,beta-lactamase_2500_259,TEM-1,beta-lactamase_2500,P62593,0.865208,NO,259,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.361275,0.0070773,0.865208 beta-lactamase_S201C,beta-lactamase_201,TEM-1,beta-lactamase,P62593,0.865258,NO,201,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.183,-4.753,3.57,4.85496,0.064,H,A,0.77,-0.07,4.045,,64.69,HPB,-1.451,0.221079,0.00198815,0.865258 beta-lactamase_0_P181S,beta-lactamase_0_181,TEM-1,beta-lactamase_0,P62593,0.865265,NO,181,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.813,-3.349,2.536,,,H,A,0.52,-1.14,1.357,,61.54,HOH,-1.795,0.0500837,0.000703122,0.865265 WW_domain_K181I,WW_domain_181,Yap65,WW_domain,P46937,0.865267,NO,181,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.35,-3.607,2.257,5.0864,,,,,,0.176,,15.87,HBP,-1.247,0.153962,0.0033022,0.865267 kka2_1:4_G99S,kka2_1:4_99,Kka2,kka2_1:4,P00552,0.865275,NO,99,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.596,-3.189,2.593,,0.368,S,g,0.29,-0.87,,,,OOP,-1.63067,0.168804,0.00186055,0.865275 beta-lactamase_G141H,beta-lactamase_141,TEM-1,beta-lactamase,P62593,0.865325,NO,141,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.828,-4.652,3.824,5.03155,0.575,T,l,0.76,-0.28,0.198,,64.69,HOO,-1.08933,0.221079,0.0012419,0.865325 beta-lactamase_0_D207G,beta-lactamase_0_207,TEM-1,beta-lactamase_0,P62593,0.865351,NO,207,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.064,-2.283,0.219,,0.409,H,A,0.75,0.12,5.277,,77.62,HAH,-1.77033,0.0500837,0.00592942,0.865351 beta-lactamase_0_D36G,beta-lactamase_0_36,TEM-1,beta-lactamase_0,P62593,0.865377,NO,36,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.732,-2.829,0.097,,0.555,H,A,0.75,1.17,13.689,13.689,77.62,AAP,-1.91167,0.0500837,0.00476483,0.865377 beta-lactamase_0_T263W,beta-lactamase_0_263,TEM-1,beta-lactamase_0,P62593,0.86541,NO,263,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.0500837,0.0110582,0.86541 PSD95pdz3_A376I,PSD95pdz3_376,PSD95pdz3,PSD95pdz3,P31016,0.865427,NO,376,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.307,-3.242,1.935,4.72134,,,,,17.108,,,,HHH,-1.49567,0.0758425,0.000341232,0.865427 kka2_1:4_D52F,kka2_1:4_52,Kka2,kka2_1:4,P00552,0.865434,NO,52,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.271,-4.344,2.073,,0.22,E,B,0.75,0.8,0.349,,71.59,PAH,-2.38367,0.168804,0.00175694,0.865434 beta-lactamase_0_T139C,beta-lactamase_0_139,TEM-1,beta-lactamase_0,P62593,0.865467,NO,139,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.901,-4.964,3.063,,0.216,H,A,0.22,0.39,0.421,,77.62,PPH,-2.04667,0.0500837,0.00441837,0.865467 beta-lactamase_625_L49N,beta-lactamase_625_49,TEM-1,beta-lactamase_625,P62593,0.865479,NO,49,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.897,-3.842,1.945,,0.131,T,A,0.55,0.04,3.112,,64.69,AHP,-1.99233,0.213352,0.00401477,0.865479 beta-lactamase_156_L284Y,beta-lactamase_156_284,TEM-1,beta-lactamase_156,P62593,0.865492,NO,284,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.111618,0.0686156,0.865492 kka2_1:4_A176W,kka2_1:4_176,Kka2,kka2_1:4,P00552,0.865494,NO,176,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.621,-5.554,3.933,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.168804,0.0083587,0.865494 kka2_1:2_F206C,kka2_1:2_206,Kka2,kka2_1:2,P00552,0.865528,NO,206,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.349,-4.946,3.597,,0.006,E,B,0.58,-1.21,0.978,,63.64,OHH,-1.04,0.295029,0.00936868,0.865528 beta-lactamase_2500_R162H,beta-lactamase_2500_162,TEM-1,beta-lactamase_2500,P62593,0.865529,NO,162,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.016,-4.37,3.354,,0.124,S,B,1.2,-0.37,6.199,,64.69,ABH,-1.25,0.361275,0.000561334,0.865529 PSD95pdz3_L342D,PSD95pdz3_342,PSD95pdz3,PSD95pdz3,P31016,0.865533,NO,342,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.347,-3.825,2.478,5.03015,,,,,12.0762,,,,HHH,-1.428,0.0758425,0.00081112,0.865533 beta-lactamase_625_R81C,beta-lactamase_625_81,TEM-1,beta-lactamase_625,P62593,0.865555,NO,81,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.466,-5.147,3.681,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.213352,0.00499763,0.865555 beta-lactamase_625_T263Y,beta-lactamase_625_263,TEM-1,beta-lactamase_625,P62593,0.865556,NO,263,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.213352,0.0110582,0.865556 kka2_1:8_V97R,kka2_1:8_97,Kka2,kka2_1:8,P00552,0.865584,NO,97,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.453,-4.167,2.714,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.100394,0.00737869,0.865584 kka2_1:8_V97R,kka2_1:8_97,Kka2,kka2_1:8,P00552,0.865584,NO,97,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.453,-4.167,2.714,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.100394,0.00737869,0.865584 beta-lactamase_L38V,beta-lactamase_38,TEM-1,beta-lactamase,P62593,0.865587,NO,38,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.343,-2.209,0.866,5.23728,0.088,H,A,1.75,0.2,1.986,,64.34,PHO,-1.78033,0.221079,0.00373244,0.865587 kka2_1:2_A150V,kka2_1:2_150,Kka2,kka2_1:2,P00552,0.8656,NO,150,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.949,-3.306,2.357,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.295029,0.0045009,0.8656 beta-lactamase_2500_S51Q,beta-lactamase_2500_51,TEM-1,beta-lactamase_2500,P62593,0.865612,NO,51,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.526,-3.91,2.384,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.361275,0.00504821,0.865612 beta-lactamase_P253D,beta-lactamase_253,TEM-1,beta-lactamase,P62593,0.865615,NO,253,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-2.253,-3.605,1.352,5.24842,0.308,,B,0.73,-0.46,2.293,,73.08,BOP,-2.10633,0.221079,0.00786358,0.865615 kka2_1:2_V97R,kka2_1:2_97,Kka2,kka2_1:2,P00552,0.86563,NO,97,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.453,-4.167,2.714,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.295029,0.00737869,0.86563 beta-lactamase_0_V106I,beta-lactamase_0_106,TEM-1,beta-lactamase_0,P62593,0.865646,NO,106,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.218,-2.124,0.906,,0.258,T,A,0.44,0.24,0.952,,72.73,OHP,-1.04933,0.0500837,0.00304168,0.865646 kka2_1:8_L107Q,kka2_1:8_107,Kka2,kka2_1:8,P00552,0.865659,NO,107,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.238,-4.215,2.977,,0.197,.,B,0.55,-1.1,4.478,,71.59,BHH,-2.143,0.100394,0.00561937,0.865659 kka2_1:8_L107Q,kka2_1:8_107,Kka2,kka2_1:8,P00552,0.865659,NO,107,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.238,-4.215,2.977,,0.197,.,B,0.55,-1.1,4.478,,71.59,BHH,-2.143,0.100394,0.00561937,0.865659 kka2_1:8_N200L,kka2_1:8_200,Kka2,kka2_1:8,P00552,0.865708,NO,200,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-2.446,-3.814,1.368,,0.756,T,L,0.43,-0.08,2.528,,64.39,APO,-2.08,0.100394,0.00838549,0.865708 kka2_1:8_N200L,kka2_1:8_200,Kka2,kka2_1:8,P00552,0.865708,NO,200,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-2.446,-3.814,1.368,,0.756,T,L,0.43,-0.08,2.528,,64.39,APO,-2.08,0.100394,0.00838549,0.865708 beta-lactamase_G154A,beta-lactamase_154,TEM-1,beta-lactamase,P62593,0.865729,NO,154,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.823,-2.356,1.533,5.40944,0.54,T,l,0.77,-0.56,2.283,,64.69,HOA,-1.635,0.221079,0.00180205,0.865729 beta-lactamase_L191C,beta-lactamase_191,TEM-1,beta-lactamase,P62593,0.865815,NO,191,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.087,-4.696,3.609,5.72226,,H,A,1.07,0.09,1.23,,63.29,BHH,-1.445,0.221079,0.00263549,0.865815 beta-lactamase_W286M,beta-lactamase_286,TEM-1,beta-lactamase,P62593,0.865815,NO,286,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-1.111,-4.297,3.186,6.64456,0.492,,?,0.01,0.6,,,,BHX,-1.478,0.221079,,0.865815 Pab1_A179H,Pab1_179,Pab1,Pab1,P04147,0.865942,NO,179,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.013,-4.497,3.484,,0.078,H,A,0.61,0.5,,,,HHB,-1.51233,0.175299,0.000291703,0.865942 beta-lactamase_0_A40H,beta-lactamase_0_40,TEM-1,beta-lactamase_0,P62593,0.865949,NO,40,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.402,-4.792,3.39,,0.155,S,B,0.46,0.21,0.783,,73.78,OHB,-1.40267,0.0500837,0.00490026,0.865949 Pab1_G188F,Pab1_188,Pab1,Pab1,P04147,0.866008,NO,188,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.809,-4.109,3.3,,0.379,E,g,,2.18,,,,POH,-1.14633,0.175299,0.000280911,0.866008 kka2_1:2_T28E,kka2_1:2_28,Kka2,kka2_1:2,P00552,0.866028,NO,28,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.883,-2.677,0.794,,0.353,S,B,0.22,2.02,2.655,,63.64,PPH,-1.74467,0.295029,0.00743084,0.866028 beta-lactamase_0_H151S,beta-lactamase_0_151,TEM-1,beta-lactamase_0,P62593,0.866051,NO,151,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-2.96,-2.636,-0.324,,0.594,H,A,0.17,0.1,9.375,,77.62,HBP,-2.34767,0.0500837,0.00216946,0.866051 beta-lactamase_0_E108F,beta-lactamase_0_108,TEM-1,beta-lactamase_0,P62593,0.866059,NO,108,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.46,-4.416,2.956,,0.572,G,A,1.04,1.87,8.602,8.602,72.73,PAB,-1.437,0.0500837,0.00413372,0.866059 beta-lactamase_39_F70R,beta-lactamase_39_70,TEM-1,beta-lactamase_39,P62593,0.86607,NO,70,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.169,-4.114,2.945,,,H,A,0.58,-1.34,1.14,,63.99,PHB,-0.980667,0.0495842,0.00193499,0.86607 kka2_1:8_L193T,kka2_1:8_193,Kka2,kka2_1:8,P00552,0.866128,NO,193,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.983,-3.533,2.55,,,G,A,1.59,-1.03,2.234,,65.53,OHO,-0.965333,0.100394,0.00480179,0.866128 kka2_1:8_L193T,kka2_1:8_193,Kka2,kka2_1:8,P00552,0.866128,NO,193,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.983,-3.533,2.55,,,G,A,1.59,-1.03,2.234,,65.53,OHO,-0.965333,0.100394,0.00480179,0.866128 beta-lactamase_0_L47Q,beta-lactamase_0_47,TEM-1,beta-lactamase_0,P62593,0.86614,NO,47,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.876,-3.17,1.294,,0.007,E,B,0.55,0.2,1.024,,67.83,AHA,-1.639,0.0500837,0.00439844,0.86614 kka2_1:4_E86K,kka2_1:4_86,Kka2,kka2_1:4,P00552,0.866167,NO,86,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.86,-3.566,1.706,,0.369,.,B,1.04,1.92,4.451,,63.26,PAH,-1.98067,0.168804,0.00642858,0.866167 beta-lactamase_0_L191V,beta-lactamase_0_191,TEM-1,beta-lactamase_0,P62593,0.866221,NO,191,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.087,-2.22,1.133,,,H,A,0.55,0.09,12.255,12.255,63.29,BHH,-1.445,0.0500837,0.00263549,0.866221 WW_domain_D201V,WW_domain_201,Yap65,WW_domain,P46937,0.866228,NO,201,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.369,-3.403,2.034,4.90312,,,,,,20.806,20.806,70.04,PAO,-1.456,0.153962,0.00248402,0.866228 beta-lactamase_G194V,beta-lactamase_194,TEM-1,beta-lactamase,P62593,0.86626,NO,194,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.396,-3.736,2.34,5.46622,0.276,S,b,0.77,0.36,3.593,,67.83,POA,-1.832,0.221079,0.00392163,0.86626 beta-lactamase_K30F,beta-lactamase_30,TEM-1,beta-lactamase,P62593,0.866281,NO,30,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-2.307,-4.338,2.031,5.30605,0.142,H,A,1.82,-0.65,2.434,,93.01,HBH,-2.32833,0.221079,0.00448593,0.866281 beta-lactamase_0_E279P,beta-lactamase_0_279,TEM-1,beta-lactamase_0,P62593,0.866309,NO,279,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.0500837,0.0192826,0.866309 kka2_1:2_P128I,kka2_1:2_128,Kka2,kka2_1:2,P00552,0.866324,NO,128,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.922,-1.808,-0.114,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.295029,0.00774689,0.866324 kka2_1:1_L47Y,kka2_1:1_47,Kka2,kka2_1:1,P00552,0.866365,NO,47,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.265,-3.972,2.707,,0.139,E,B,0.55,-0.86,14.593,14.593,63.26,HHH,-1.77933,0.520039,0.00509386,0.866365 beta-lactamase_F70H,beta-lactamase_70,TEM-1,beta-lactamase,P62593,0.86642,NO,70,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.169,-4.494,3.325,5.42055,,H,A,1.1,-1.34,1.14,,63.99,PHB,-0.980667,0.221079,0.00193499,0.86642 beta-lactamase_R176W,beta-lactamase_176,TEM-1,beta-lactamase,P62593,0.86642,NO,176,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-0.863,-5.322,4.459,5.61264,0.385,T,B,0.68,-0.63,,,,ABA,-1.38867,0.221079,0.00105554,0.86642 beta-lactamase_Y95M,beta-lactamase_95,TEM-1,beta-lactamase,P62593,0.86642,NO,95,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-1.715,-4.404,2.689,5.67068,0.122,,b,0.96,-0.37,2.341,,77.62,BHP,-2.16167,0.221079,0.00479449,0.86642 kka2_1:2_E230M,kka2_1:2_230,Kka2,kka2_1:2,P00552,0.866454,NO,230,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.672,-4.815,2.143,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.295029,0.00920051,0.866454 kka2_1:2_N200S,kka2_1:2_200,Kka2,kka2_1:2,P00552,0.866468,NO,200,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-2.446,-2.785,0.339,,0.756,T,L,0.61,-0.08,2.836,,64.39,APO,-2.08,0.295029,0.00838549,0.866468 beta-lactamase_2500_G234A,beta-lactamase_2500_234,TEM-1,beta-lactamase_2500,P62593,0.866469,NO,234,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.62,-2.853,2.233,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.361275,0.000889577,0.866469 kka2_1:8_S105H,kka2_1:8_105,Kka2,kka2_1:8,P00552,0.866474,NO,105,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.945,-4.83,2.885,,0.056,S,B,0.27,-1.04,2.115,,65.53,PPB,-2.17033,0.100394,0.00847233,0.866474 kka2_1:8_S105H,kka2_1:8_105,Kka2,kka2_1:8,P00552,0.866474,NO,105,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.945,-4.83,2.885,,0.056,S,B,0.27,-1.04,2.115,,65.53,PPB,-2.17033,0.100394,0.00847233,0.866474 beta-lactamase_2500_P250N,beta-lactamase_2500_250,TEM-1,beta-lactamase_2500,P62593,0.866555,NO,250,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.361275,0.00550899,0.866555 beta-lactamase_0_W288A,beta-lactamase_0_288,TEM-1,beta-lactamase_0,P62593,0.866559,NO,288,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,,,,,,,,,,,,,BHO,,0.0500837,,0.866559 beta-lactamase_A222L,beta-lactamase_222,TEM-1,beta-lactamase,P62593,0.866594,NO,222,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.103,-3.403,1.3,5.2262,0.233,H,A,0.47,-0.25,0.379,,77.62,PHH,-1.63733,0.221079,0.00466094,0.866594 kka2_1:8_A34V,kka2_1:8_34,Kka2,kka2_1:8,P00552,0.866597,NO,34,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.928,-3.231,2.303,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.100394,0.00343484,0.866597 kka2_1:8_A34V,kka2_1:8_34,Kka2,kka2_1:8,P00552,0.866597,NO,34,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.928,-3.231,2.303,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.100394,0.00343484,0.866597 beta-lactamase_0_W227L,beta-lactamase_0_227,TEM-1,beta-lactamase_0,P62593,0.866616,NO,227,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-0.982,-3.387,2.405,,0.272,,B,0.47,-0.29,3.782,,74.48,OHH,-1.595,0.0500837,0.00226019,0.866616 beta-lactamase_0_L167G,beta-lactamase_0_167,TEM-1,beta-lactamase_0,P62593,0.866627,NO,167,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.138,-3.694,2.556,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.0500837,0.00303566,0.866627 beta-lactamase_0_A225V,beta-lactamase_0_225,TEM-1,beta-lactamase_0,P62593,0.866642,NO,225,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.845,-3.655,1.81,,1,T,B,0.46,-0.38,11.722,11.722,74.48,OHO,-1.39967,0.0500837,0.00465057,0.866642 beta-lactamase_L28N,beta-lactamase_28,TEM-1,beta-lactamase,P62593,0.866677,NO,28,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.579,-4.056,2.477,5.42969,0.277,H,A,0.07,-0.16,19.748,19.748,93.01,PHH,-2.11333,0.221079,0.00359321,0.866677 beta-lactamase_T147M,beta-lactamase_147,TEM-1,beta-lactamase,P62593,0.866677,NO,147,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.149,-4.573,3.424,5.37474,0.281,H,A,0.8,-0.68,2.838,,64.34,HPH,-1.456,0.221079,0.00226017,0.866677 beta-lactamase_Y103H,beta-lactamase_103,TEM-1,beta-lactamase,P62593,0.866677,NO,103,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-1.33,-2.243,0.913,5.71734,0.613,S,l,2.55,1.21,5.721,,63.29,AHP,-1.48767,0.221079,0.00443048,0.866677 beta-lactamase_0_T187M,beta-lactamase_0_187,TEM-1,beta-lactamase_0,P62593,0.866718,NO,187,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.401,-4.516,3.115,,0.007,H,A,0.22,-1.19,3.259,,67.48,PPH,-1.69633,0.0500837,0.00491782,0.866718 beta-lactamase_G251V,beta-lactamase_251,TEM-1,beta-lactamase,P62593,0.866725,NO,251,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.907,-3.667,1.76,5.33865,0.506,T,l,0.73,0.17,10.663,,65.38,AOB,-2.06067,0.221079,0.00733416,0.866725 kka2_1:1_L53P,kka2_1:1_53,Kka2,kka2_1:1,P00552,0.866745,NO,53,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-2.681,-2.005,-0.676,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.520039,0.00671168,0.866745 beta-lactamase_156_G281Q,beta-lactamase_156_281,TEM-1,beta-lactamase_156,P62593,0.866784,NO,281,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.111618,0.0406482,0.866784 beta-lactamase_625_D48T,beta-lactamase_625_48,TEM-1,beta-lactamase_625,P62593,0.866789,NO,48,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.101,-3.511,2.41,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.213352,0.0027273,0.866789 gb1_T243D,gb1_243,gb1,gb1,P06654,0.866794,NO,243,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.415,-3.349,1.934,,,,,,,1.083,,37.28,PPP,-1.43233,0.177985,0.00308687,0.866794 beta-lactamase_156_L79S,beta-lactamase_156_79,TEM-1,beta-lactamase_156,P62593,0.866844,NO,79,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.842,-3.608,2.766,,0.007,H,A,0.55,-0.16,1.831,,50.35,HHP,-1.44333,0.111618,0.000947397,0.866844 beta-lactamase_2500_K286W,beta-lactamase_2500_286,TEM-1,beta-lactamase_2500,P62593,0.866855,NO,286,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.111,-3.724,2.613,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.361275,,0.866855 beta-lactamase_0_S51I,beta-lactamase_0_51,TEM-1,beta-lactamase_0,P62593,0.866862,NO,51,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.526,-3.925,2.399,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.0500837,0.00504821,0.866862 kka2_1:8_A110S,kka2_1:8_110,Kka2,kka2_1:8,P00552,0.866868,NO,110,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.064,-2.748,0.684,,0.175,H,A,1.04,-1.19,11.413,11.413,71.59,OHA,-1.91867,0.100394,0.00759851,0.866868 kka2_1:8_A110S,kka2_1:8_110,Kka2,kka2_1:8,P00552,0.866868,NO,110,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.064,-2.748,0.684,,0.175,H,A,1.04,-1.19,11.413,11.413,71.59,OHA,-1.91867,0.100394,0.00759851,0.866868 beta-lactamase_0_G141E,beta-lactamase_0_141,TEM-1,beta-lactamase_0,P62593,0.866874,NO,141,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.828,-2.606,1.778,,0.575,T,l,0.29,-0.28,0.722,,64.69,HOO,-1.08933,0.0500837,0.0012419,0.866874 beta-lactamase_625_L197S,beta-lactamase_625_197,TEM-1,beta-lactamase_625,P62593,0.866898,NO,197,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.853,-3.532,2.679,,0.007,S,B,0.55,0.33,1.756,,60.14,HHP,-1.833,0.213352,0.00144602,0.866898 WW_domain_L190R,WW_domain_190,Yap65,WW_domain,P46937,0.866905,NO,190,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.404,-3.867,2.463,5.53598,,,,,,0.645,,56.55,HHP,-1.51833,0.153962,0.00249186,0.866905 beta-lactamase_E62Q,beta-lactamase_62,TEM-1,beta-lactamase,P62593,0.86691,NO,62,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.193,-2.5,1.307,5.93066,0.342,S,B,1.52,-0.3,3.139,,73.08,AAB,-1.417,0.221079,0.00264802,0.86691 beta-lactamase_N173P,beta-lactamase_173,TEM-1,beta-lactamase,P62593,0.86691,NO,173,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-2.663,-3.891,1.228,7.02497,1.044,T,l,0.09,1.25,1.88,,77.62,OPA,-1.46633,0.221079,0.0033769,0.86691 kka2_1:2_A35W,kka2_1:2_35,Kka2,kka2_1:2,P00552,0.866915,NO,35,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.127,-5.562,3.435,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.295029,0.00630016,0.866915 kka2_1:8_P194T,kka2_1:8_194,Kka2,kka2_1:8,P00552,0.866942,NO,194,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.846,-3.444,2.598,,0.308,G,A,0.52,-1.19,4.861,,53.03,HOP,-0.888333,0.100394,0.00314194,0.866942 kka2_1:8_P194T,kka2_1:8_194,Kka2,kka2_1:8,P00552,0.866942,NO,194,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.846,-3.444,2.598,,0.308,G,A,0.52,-1.19,4.861,,53.03,HOP,-0.888333,0.100394,0.00314194,0.866942 kka2_1:2_L94V,kka2_1:2_94,Kka2,kka2_1:2,P00552,0.86698,NO,94,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.618,-2.483,0.865,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.295029,0.00520888,0.86698 beta-lactamase_0_D177M,beta-lactamase_0_177,TEM-1,beta-lactamase_0,P62593,0.866984,NO,177,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.967,-4.928,3.961,,0.006,T,L,0.75,-1.02,3.536,,64.69,BAP,-0.873667,0.0500837,0.000864022,0.866984 kka2_1:2_P45H,kka2_1:2_45,Kka2,kka2_1:2,P00552,0.86699,NO,45,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.774,-4.807,3.033,,0.669,,B,0.52,-0.76,4.882,,71.59,BOH,-2.152,0.295029,0.00590481,0.86699 beta-lactamase_G251I,beta-lactamase_251,TEM-1,beta-lactamase,P62593,0.867006,NO,251,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.907,-3.207,1.3,5.33865,0.506,T,l,0.73,0.17,10.663,,65.38,AOB,-2.06067,0.221079,0.00733416,0.867006 beta-lactamase_M67I,beta-lactamase_67,TEM-1,beta-lactamase,P62593,0.867018,NO,67,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-2.231,-2.93,0.699,4.9618,0.006,G,P,1.07,-0.81,1.463,,65.03,HHP,-1.502,0.221079,0.00409753,0.867018 beta-lactamase_I229L,beta-lactamase_229,TEM-1,beta-lactamase,P62593,0.867042,NO,229,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.267,-2.225,0.958,5.0911,0.083,E,B,1,-0.76,1.114,,50,HHH,-1.58767,0.221079,0.00477249,0.867042 beta-lactamase_2500_M67L,beta-lactamase_2500_67,TEM-1,beta-lactamase_2500,P62593,0.867048,NO,67,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-2.231,-2.657,0.426,,0.006,G,P,0.55,-0.81,2.653,,65.03,HHP,-1.502,0.361275,0.00409753,0.867048 kka2_1:1_A87E,kka2_1:1_87,Kka2,kka2_1:1,P00552,0.867063,NO,87,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.917,-2.476,0.559,,1.039,S,L,0.46,1.57,20.738,20.738,65.53,AHO,-1.822,0.520039,0.00791281,0.867063 PSD95pdz3_G322F,PSD95pdz3_322,PSD95pdz3,PSD95pdz3,P31016,0.867079,NO,322,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.008,-3.974,2.966,5.24791,,,,,16.3275,,,,POH,-1.24867,0.0758425,0.00105821,0.867079 beta-lactamase_D212N,beta-lactamase_212,TEM-1,beta-lactamase,P62593,0.867121,NO,212,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.624,-1.899,0.275,4.9705,0.037,,b,1.3,-0.58,12.482,,74.48,HAB,-1.77667,0.221079,0.00644302,0.867121 beta-lactamase_0_L150G,beta-lactamase_0_150,TEM-1,beta-lactamase_0,P62593,0.867133,NO,150,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.326,-3.622,2.296,,,H,A,0.55,-0.2,2.128,,62.94,HHB,-1.86167,0.0500837,0.00463171,0.867133 beta-lactamase_M268G,beta-lactamase_268,TEM-1,beta-lactamase,P62593,0.867188,NO,268,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-2.023,-3.663,1.64,5.4797,0.471,H,A,0.09,0.3,1.071,,65.73,PHA,-2.16233,0.221079,0.0102525,0.867188 beta-lactamase_0_H156E,beta-lactamase_0_156,TEM-1,beta-lactamase_0,P62593,0.867199,NO,156,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-3.156,-2.577,-0.579,,0.753,S,A,0.17,-0.6,23.367,23.367,77.62,ABH,-1.932,0.0500837,0.00468596,0.867199 kka2_1:2_R147G,kka2_1:2_147,Kka2,kka2_1:2,P00552,0.867208,NO,147,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.123,-3.428,2.305,,0.094,H,A,1.2,0.97,0.425,,64.02,PBH,-1.98267,0.295029,0.00549168,0.867208 Pab1_L186W,Pab1_186,Pab1,Pab1,P04147,0.867231,NO,186,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.783,-5.207,3.424,,,,,,,,,,HHP,-1.56967,0.175299,0.00154968,0.867231 kka2_1:8_L123M,kka2_1:8_123,Kka2,kka2_1:8,P00552,0.867238,NO,123,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.888,-2.619,1.731,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.100394,0.00325188,0.867238 kka2_1:8_L123M,kka2_1:8_123,Kka2,kka2_1:8,P00552,0.867238,NO,123,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.888,-2.619,1.731,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.100394,0.00325188,0.867238 beta-lactamase_D99Y,beta-lactamase_99,TEM-1,beta-lactamase,P62593,0.867252,NO,99,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.191,-4.234,3.043,5.66081,0.402,G,A,0.23,0.36,1.318,,64.69,PAH,-1.794,0.221079,0.00305446,0.867252 PSD95pdz3_E373C,PSD95pdz3_373,PSD95pdz3,PSD95pdz3,P31016,0.867341,NO,373,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.404,-4.994,3.59,5.79743,,,,,27.9833,,,,BAP,-1.57667,0.0758425,0.000387698,0.867341 beta-lactamase_2500_L73F,beta-lactamase_2500_73,TEM-1,beta-lactamase_2500,P62593,0.867346,NO,73,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.507,-2.19,0.683,,,H,A,0.55,-0.64,2.178,,67.83,HHH,-1.487,0.361275,0.00488983,0.867346 kka2_1:4_H124N,kka2_1:4_124,Kka2,kka2_1:4,P00552,0.867392,NO,124,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-0.84,-3.251,2.411,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.168804,0.00211296,0.867392 beta-lactamase_I256M,beta-lactamase_256,TEM-1,beta-lactamase,P62593,0.867434,NO,256,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.621,-2.921,1.3,5.3196,,E,B,1,-0.84,1.615,,73.08,BHH,-1.80667,0.221079,0.00710634,0.867434 beta-lactamase_R159N,beta-lactamase_159,TEM-1,beta-lactamase,P62593,0.867491,NO,159,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-0.94,-3.445,2.505,5.64971,0.316,,B,0.68,-0.55,1.172,,64.34,PBH,-1.011,0.221079,0.00108472,0.867491 beta-lactamase_0_A230T,beta-lactamase_0_230,TEM-1,beta-lactamase_0,P62593,0.867494,NO,230,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.154,-3.381,2.227,,0.01,E,B,0.46,-1.17,2.179,,50,HHA,-1.079,0.0500837,0.00516841,0.867494 beta-lactamase_2500_A77I,beta-lactamase_2500_77,TEM-1,beta-lactamase_2500,P62593,0.867497,NO,77,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.234,-3.583,2.349,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.361275,0.00282362,0.867497 Pab1_L191G,Pab1_191,Pab1,Pab1,P04147,0.867549,NO,191,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.2,-3.622,2.422,,0.204,E,B,,2.24,,,,HHP,-1.20133,0.175299,0.000583797,0.867549 beta-lactamase_625_E35S,beta-lactamase_625_35,TEM-1,beta-lactamase_625,P62593,0.867581,NO,35,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-0.869,-3.186,2.317,,0.15,H,A,1.04,0.21,0.664,,46.85,HAA,-1.88667,0.213352,0.00174441,0.867581 beta-lactamase_0_F64E,beta-lactamase_0_64,TEM-1,beta-lactamase_0,P62593,0.867703,NO,64,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-0.841,-3.89,3.049,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.0500837,0.000947691,0.867703 hsp90_F583G,hsp90_583,hsp90,hsp90,P02829,0.867795,NO,583,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-3.22,-2.511,0,5.28185,1.112,S,l,1.1,0.87,,,,PHO,-3.003,0.368192,0.000222939,0.867795 beta-lactamase_A183P,beta-lactamase_183,TEM-1,beta-lactamase,P62593,0.867852,NO,183,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.231,-3.812,2.581,4.84712,0.155,H,A,0.55,-0.91,12.189,,77.62,HHH,-1.53367,0.221079,0.00296631,0.867852 kka2_1:8_D183M,kka2_1:8_183,Kka2,kka2_1:8,P00552,0.867877,NO,183,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.204,-4.843,3.639,,0.518,.,b,0.75,0.25,0.347,,52.27,AAH,-1.40533,0.100394,0.00426304,0.867877 kka2_1:8_D183M,kka2_1:8_183,Kka2,kka2_1:8,P00552,0.867877,NO,183,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.204,-4.843,3.639,,0.518,.,b,0.75,0.25,0.347,,52.27,AAH,-1.40533,0.100394,0.00426304,0.867877 gb1_Y271L,gb1_271,gb1,gb1,P06654,0.867895,NO,271,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-1.181,-2.91,1.729,,,,,,,,,,PHA,-1.92933,0.177985,0.00236544,0.867895 kka2_1:4_D157H,kka2_1:4_157,Kka2,kka2_1:4,P00552,0.867944,NO,157,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.993,-4.51,3.517,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.168804,0.0042313,0.867944 PSD95pdz3_F337V,PSD95pdz3_337,PSD95pdz3,PSD95pdz3,P31016,0.867945,NO,337,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.524,-2.985,1.461,5.22838,,,,,13.4936,,,,HHH,-1.59467,0.0758425,0.000875287,0.867945 beta-lactamase_0_Q204G,beta-lactamase_0_204,TEM-1,beta-lactamase_0,P62593,0.867953,NO,204,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-1.382,-3.474,2.092,,0.204,H,A,0.64,0.09,2.646,,66.08,PPH,-1.49067,0.0500837,0.00364106,0.867953 kka2_1:2_P76S,kka2_1:2_76,Kka2,kka2_1:2,P00552,0.86796,NO,76,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.449,-2.672,1.223,,0.331,.,B,0.52,-0.41,0.345,,63.64,HOO,-1.662,0.295029,0.00625685,0.86796 kka2_1:4_P76Q,kka2_1:4_76,Kka2,kka2_1:4,P00552,0.868028,NO,76,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.449,-3.171,1.722,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.168804,0.00625685,0.868028 beta-lactamase_A200W,beta-lactamase_200,TEM-1,beta-lactamase,P62593,0.868073,NO,200,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.878,-5.525,3.647,5.19406,0.757,H,A,0.47,-0.19,0.436,,77.62,HHP,-2.001,0.221079,0.0060056,0.868073 beta-lactamase_0_G90V,beta-lactamase_0_90,TEM-1,beta-lactamase_0,P62593,0.868174,NO,90,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-2.091,-3.033,0.942,,0.598,T,A,0.29,0.32,2.04,,77.62,HOB,-1.52633,0.0500837,0.00490273,0.868174 beta-lactamase_P165A,beta-lactamase_165,TEM-1,beta-lactamase,P62593,0.868179,NO,165,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.373,-3.022,1.649,5.33889,0.203,T,A,0.99,-0.31,0.414,,73.78,AOA,-1.359,0.221079,0.00549538,0.868179 kka2_1:8_S32V,kka2_1:8_32,Kka2,kka2_1:8,P00552,0.868197,NO,32,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-0.804,-3.557,2.753,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.100394,0.00149998,0.868197 kka2_1:8_S32V,kka2_1:8_32,Kka2,kka2_1:8,P00552,0.868197,NO,32,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-0.804,-3.557,2.753,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.100394,0.00149998,0.868197 beta-lactamase_2500_L111K,beta-lactamase_2500_111,TEM-1,beta-lactamase_2500,P62593,0.868214,NO,111,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.76,-3.773,2.013,,0.328,T,A,0.55,0.93,1.966,,64.34,BHP,-1.884,0.361275,0.00480671,0.868214 beta-lactamase_L49S,beta-lactamase_49,TEM-1,beta-lactamase,P62593,0.868232,NO,49,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.897,-2.417,0.52,5.86005,0.131,T,A,1.3,0.04,3.112,,64.69,AHP,-1.99233,0.221079,0.00401477,0.868232 PSD95pdz3_F340E,PSD95pdz3_340,PSD95pdz3,PSD95pdz3,P31016,0.868238,NO,340,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.524,-3.572,2.048,5.79283,,,,,11.8045,,,,PHH,-1.55767,0.0758425,0.000836987,0.868238 E1_Ubiquitin_K48E,E1_Ubiquitin_48,Uba1,E1_Ubiquitin,P0CG63,0.868258,NO,48,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.219,-2.004,0.785,,0.132,E,B,,-0.28,,,,OBO,-1.109,0.18783,0.00100363,0.868258 gb1_A252T,gb1_252,gb1,gb1,P06654,0.86826,NO,252,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.175,-2.932,1.757,,,,,,,,,,PHA,-1.55967,0.177985,0.00125598,0.86826 gb1_T242A,gb1_242,gb1,gb1,P06654,0.86826,NO,242,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.245,-2.588,1.343,,,,,,,,,,APP,-1.444,0.177985,0.00243886,0.86826 beta-lactamase_156_K213D,beta-lactamase_156_213,TEM-1,beta-lactamase_156,P62593,0.868271,NO,213,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.81,-3.577,1.767,,0.67,,A,2.34,0.29,3.924,,67.83,ABH,-1.57767,0.111618,0.00610411,0.868271 beta-lactamase_0_T116G,beta-lactamase_0_116,TEM-1,beta-lactamase_0,P62593,0.868296,NO,116,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.28,-3.287,2.007,,0.115,E,B,0.22,-0.12,1.356,,67.48,HPH,-1.39967,0.0500837,0.00336175,0.868296 beta-lactamase_156_P143D,beta-lactamase_156_143,TEM-1,beta-lactamase_156,P62593,0.868358,NO,143,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.967,-3.622,2.655,,0.075,H,A,0.52,-0.37,0.479,,66.78,OOB,-1.354,0.111618,0.00114551,0.868358 kka2_1:8_L60S,kka2_1:8_60,Kka2,kka2_1:8,P00552,0.868368,NO,60,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.997,-3.713,2.716,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.100394,0.00262176,0.868368 kka2_1:8_L60S,kka2_1:8_60,Kka2,kka2_1:8,P00552,0.868368,NO,60,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.997,-3.713,2.716,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.100394,0.00262176,0.868368 beta-lactamase_0_V42W,beta-lactamase_0_42,TEM-1,beta-lactamase_0,P62593,0.86859,NO,42,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.564,-5.336,3.772,,0.017,E,B,0.44,-0.51,1.659,,63.99,BHO,-1.042,0.0500837,0.00404515,0.86859 beta-lactamase_0_S221V,beta-lactamase_0_221,TEM-1,beta-lactamase_0,P62593,0.868597,NO,221,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.754,-3.416,1.662,,0.624,H,A,0.27,-0.2,2.914,,74.48,BPH,-1.59967,0.0500837,0.0046094,0.868597 beta-lactamase_0_D33N,beta-lactamase_0_33,TEM-1,beta-lactamase_0,P62593,0.868632,NO,33,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.321,-2.983,0.662,,0.366,H,A,0.75,0.33,12.514,12.514,77.62,BAH,-2.12133,0.0500837,0.00435556,0.868632 kka2_1:2_A56C,kka2_1:2_56,Kka2,kka2_1:2,P00552,0.868653,NO,56,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.083,-5.094,3.011,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.295029,0.00717715,0.868653 beta-lactamase_0_L137G,beta-lactamase_0_137,TEM-1,beta-lactamase_0,P62593,0.86868,NO,137,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.03,-3.837,2.807,,,H,A,0.55,-0.38,0.328,,42.31,HHP,-1.58933,0.0500837,0.00278599,0.86868 kka2_1:1_H124Q,kka2_1:1_124,Kka2,kka2_1:1,P00552,0.868682,NO,124,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-0.84,-3.703,2.863,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.520039,0.00211296,0.868682 beta-lactamase_R7D,beta-lactamase_7,TEM-1,beta-lactamase,P62593,0.868689,NO,7,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.683,-3.784,2.101,,,,,,,2.44,,67.13,HBH,-1.96267,0.221079,0.00211375,0.868689 beta-lactamase_0_S68P,beta-lactamase_0_68,TEM-1,beta-lactamase_0,P62593,0.868773,NO,68,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-0.913,-3.704,2.791,,0.064,G,A,0.27,-1.03,1.441,,64.69,HPP,-1.37233,0.0500837,0.000800065,0.868773 Pab1_T145K,Pab1_145,Pab1,Pab1,P04147,0.868781,NO,145,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.067,-3.274,2.207,,0.237,H,A,0.3,0.69,,,,APH,-1.135,0.175299,0.000331088,0.868781 beta-lactamase_0_D177T,beta-lactamase_0_177,TEM-1,beta-lactamase_0,P62593,0.868796,NO,177,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.967,-3.465,2.498,,0.006,T,L,0.75,-1.02,3.536,,64.69,BAP,-0.873667,0.0500837,0.000864022,0.868796 beta-lactamase_P165K,beta-lactamase_165,TEM-1,beta-lactamase,P62593,0.868886,NO,165,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.373,-3.528,2.155,5.33889,0.203,T,A,0.99,-0.31,0.414,,73.78,AOA,-1.359,0.221079,0.00549538,0.868886 PSD95pdz3_L367S,PSD95pdz3_367,PSD95pdz3,PSD95pdz3,P31016,0.868898,NO,367,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.347,-3.292,1.945,5.47696,,,,,17.0063,,,,AHB,-1.39767,0.0758425,0.000466436,0.868898 beta-lactamase_0_V260S,beta-lactamase_0_260,TEM-1,beta-lactamase_0,P62593,0.86891,NO,260,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.0500837,0.00471757,0.86891 beta-lactamase_V82Y,beta-lactamase_82,TEM-1,beta-lactamase,P62593,0.869058,NO,82,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.325,-4.133,2.808,5.27777,0.267,H,A,0.96,0.08,1.379,,93.01,BHA,-1.28567,0.221079,0.00397046,0.869058 kka2_1:8_F206C,kka2_1:8_206,Kka2,kka2_1:8,P00552,0.869079,NO,206,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.349,-4.946,3.597,,0.006,E,B,1.62,-1.21,1.052,,63.64,OHH,-1.04,0.100394,0.00936868,0.869079 kka2_1:8_F206C,kka2_1:8_206,Kka2,kka2_1:8,P00552,0.869079,NO,206,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.349,-4.946,3.597,,0.006,E,B,1.62,-1.21,1.052,,63.64,OHH,-1.04,0.100394,0.00936868,0.869079 beta-lactamase_2500_E26W,beta-lactamase_2500_26,TEM-1,beta-lactamase_2500,P62593,0.869087,NO,26,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.454,-5.402,2.948,,0.54,H,A,1.04,0.98,0.49,,93.01,OAP,-1.96167,0.361275,0.00297948,0.869087 kka2_1:1_P249A,kka2_1:1_249,Kka2,kka2_1:1,P00552,0.869212,NO,249,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.867,-2.101,0.234,,0.406,.,B,0.52,-0.01,8.037,8.037,92.05,HOA,-1.66867,0.520039,0.011045,0.869212 kka2_1:8_R38I,kka2_1:8_38,Kka2,kka2_1:8,P00552,0.869221,NO,38,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.207,-3.515,2.308,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.100394,0.00372499,0.869221 kka2_1:8_R38I,kka2_1:8_38,Kka2,kka2_1:8,P00552,0.869221,NO,38,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.207,-3.515,2.308,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.100394,0.00372499,0.869221 kka2_1:4_A255V,kka2_1:4_255,Kka2,kka2_1:4,P00552,0.869228,NO,255,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.715,-3.655,1.94,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.168804,0.0126809,0.869228 PSD95pdz3_R312L,PSD95pdz3_312,PSD95pdz3,PSD95pdz3,P31016,0.869241,NO,312,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.582,-3.04,1.458,5.76826,,,,,12.2409,,,,OBB,-1.46667,0.0758425,0.00196255,0.869241 PSD95pdz3_A382W,PSD95pdz3_382,PSD95pdz3,PSD95pdz3,P31016,0.869266,NO,382,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.307,-5.004,3.697,5.30282,,,,,22.472,,,,PHO,-1.24167,0.0758425,0.000249256,0.869266 beta-lactamase_D212Q,beta-lactamase_212,TEM-1,beta-lactamase,P62593,0.869291,NO,212,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.624,-3.949,2.325,4.9705,0.037,,b,1.3,-0.58,12.482,,74.48,HAB,-1.77667,0.221079,0.00644302,0.869291 beta-lactamase_156_L188Q,beta-lactamase_156_188,TEM-1,beta-lactamase_156,P62593,0.869328,NO,188,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.166,-4.055,2.889,,,H,A,0.55,-0.3,1.574,,60.14,PHB,-1.47033,0.111618,0.00295687,0.869328 beta-lactamase_0_H151L,beta-lactamase_0_151,TEM-1,beta-lactamase_0,P62593,0.869359,NO,151,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-2.96,-3.494,0.534,,0.594,H,A,0.17,0.1,9.375,,77.62,HBP,-2.34767,0.0500837,0.00216946,0.869359 beta-lactamase_M67H,beta-lactamase_67,TEM-1,beta-lactamase,P62593,0.869359,NO,67,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-2.231,-4.763,2.532,4.9618,0.006,G,P,1.07,-0.81,1.463,,65.03,HHP,-1.502,0.221079,0.00409753,0.869359 kka2_1:8_H188P,kka2_1:8_188,Kka2,kka2_1:8,P00552,0.869373,NO,188,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-0.913,-3.906,2.993,,0.006,,A,0.87,-1.02,1.241,,47.73,PBO,-0.927333,0.100394,0.00273139,0.869373 kka2_1:8_H188P,kka2_1:8_188,Kka2,kka2_1:8,P00552,0.869373,NO,188,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-0.913,-3.906,2.993,,0.006,,A,0.87,-1.02,1.241,,47.73,PBO,-0.927333,0.100394,0.00273139,0.869373 beta-lactamase_0_G142D,beta-lactamase_0_142,TEM-1,beta-lactamase_0,P62593,0.869391,NO,142,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.707,-3.466,2.759,,0.034,,p,0.29,-0.64,1.947,,64.69,OOO,-0.834,0.0500837,0.00060149,0.869391 beta-lactamase_Q4Q,beta-lactamase_4,TEM-1,beta-lactamase,P62593,0.869392,NO,4,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,,,,,,,,,,,,,HPB,,0.221079,0.00316562,0.869392 beta-lactamase_0_Y103E,beta-lactamase_0_103,TEM-1,beta-lactamase_0,P62593,0.869433,NO,103,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-1.33,-3.564,2.234,,0.613,S,l,0.21,1.21,1.646,,63.29,AHP,-1.48767,0.0500837,0.00443048,0.869433 Pab1_D138A,Pab1_138,Pab1,Pab1,P04147,0.869434,NO,138,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.128,-3.113,1.985,,0.427,,B,,-0.03,,,,HAP,-1.13967,0.175299,0.000567877,0.869434 beta-lactamase_0_A185M,beta-lactamase_0_185,TEM-1,beta-lactamase_0,P62593,0.869453,NO,185,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.406,-4.39,2.984,,,H,A,0.46,-1.02,1.203,,65.03,HHP,-1.84033,0.0500837,0.00467449,0.869453 beta-lactamase_2500_Q204D,beta-lactamase_2500_204,TEM-1,beta-lactamase_2500,P62593,0.869461,NO,204,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-1.382,-3.553,2.171,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.361275,0.00364106,0.869461 kka2_1:8_P128S,kka2_1:8_128,Kka2,kka2_1:8,P00552,0.869497,NO,128,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.922,-3.672,1.75,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.100394,0.00774689,0.869497 kka2_1:8_P128S,kka2_1:8_128,Kka2,kka2_1:8,P00552,0.869497,NO,128,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.922,-3.672,1.75,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.100394,0.00774689,0.869497 PSD95pdz3_R368P,PSD95pdz3_368,PSD95pdz3,PSD95pdz3,P31016,0.869509,NO,368,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.582,-3.561,1.979,6.13355,,,,,18.1818,,,,HBP,-1.50033,0.0758425,0.000451517,0.869509 Pab1_L191H,Pab1_191,Pab1,Pab1,P04147,0.869521,NO,191,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.2,-4.719,3.519,,0.204,E,B,,2.24,,,,HHP,-1.20133,0.175299,0.000583797,0.869521 beta-lactamase_M184L,beta-lactamase_184,TEM-1,beta-lactamase,P62593,0.869528,NO,184,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.593,-2.806,1.213,5.39575,,H,A,1.3,-0.87,2.893,,62.94,HHH,-1.41,0.221079,0.00356019,0.869528 beta-lactamase_2500_D252P,beta-lactamase_2500_252,TEM-1,beta-lactamase_2500,P62593,0.869559,NO,252,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.94,,,,0.766,,B,1.59,1.16,,,67.83,OAO,-2.0965,0.361275,0.00575769,0.869559 kka2_1:8_F37S,kka2_1:8_37,Kka2,kka2_1:8,P00552,0.869593,NO,37,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.427,-2.956,1.529,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.100394,0.00586193,0.869593 kka2_1:8_F37S,kka2_1:8_37,Kka2,kka2_1:8,P00552,0.869593,NO,37,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.427,-2.956,1.529,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.100394,0.00586193,0.869593 kka2_1:2_G151R,kka2_1:2_151,Kka2,kka2_1:2,P00552,0.869666,NO,151,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.873,-2.905,2.032,,0.678,T,l,0.29,1.36,1.357,,49.62,HOH,-1.11433,0.295029,0.00339918,0.869666 beta-lactamase_0_P255W,beta-lactamase_0_255,TEM-1,beta-lactamase_0,P62593,0.869683,NO,255,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.0500837,0.00499612,0.869683 gb1_F256W,gb1_256,gb1,gb1,P06654,0.869713,NO,256,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.241,-4.199,2.958,,,,,,,,,,HHB,-2.04767,0.177985,0.00435993,0.869713 beta-lactamase_0_W227K,beta-lactamase_0_227,TEM-1,beta-lactamase_0,P62593,0.869731,NO,227,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-0.982,-3.931,2.949,,0.272,,B,0.47,-0.29,3.782,,74.48,OHH,-1.595,0.0500837,0.00226019,0.869731 beta-lactamase_V106D,beta-lactamase_106,TEM-1,beta-lactamase,P62593,0.869743,NO,106,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.218,-4.056,2.838,5.23115,0.258,T,A,0.96,0.24,1.188,,72.73,OHP,-1.04933,0.221079,0.00304168,0.869743 beta-lactamase_0_S266W,beta-lactamase_0_266,TEM-1,beta-lactamase_0,P62593,0.869843,NO,266,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.0500837,0.0140785,0.869843 beta-lactamase_P217C,beta-lactamase_217,TEM-1,beta-lactamase,P62593,0.869849,NO,217,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-2.062,-5.064,3.002,5.19872,0.496,I,A,0.99,-0.33,0.431,,74.48,OOH,-1.64333,0.221079,0.00463211,0.869849 kka2_1:8_E182K,kka2_1:8_182,Kka2,kka2_1:8,P00552,0.869861,NO,182,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.516,-3.472,1.956,,0.326,,B,1.52,0.75,2.568,,65.53,OAA,-1.806,0.100394,0.00641548,0.869861 kka2_1:8_E182K,kka2_1:8_182,Kka2,kka2_1:8,P00552,0.869861,NO,182,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.516,-3.472,1.956,,0.326,,B,1.52,0.75,2.568,,65.53,OAA,-1.806,0.100394,0.00641548,0.869861 kka2_1:2_T125L,kka2_1:2_125,Kka2,kka2_1:2,P00552,0.869877,NO,125,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.622,-3.575,0.953,,0.791,T,A,0.22,0.33,2.029,,92.05,BPH,-1.56933,0.295029,0.00821755,0.869877 kka2_1:8_A78R,kka2_1:8_78,Kka2,kka2_1:8,P00552,0.869959,NO,78,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.744,-3.937,2.193,,0.078,,B,1.04,-0.53,1.251,,56.06,OHH,-1.863,0.100394,0.00457299,0.869959 kka2_1:8_A78R,kka2_1:8_78,Kka2,kka2_1:8,P00552,0.869959,NO,78,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.744,-3.937,2.193,,0.078,,B,1.04,-0.53,1.251,,56.06,OHH,-1.863,0.100394,0.00457299,0.869959 kka2_1:8_L212T,kka2_1:8_212,Kka2,kka2_1:8,P00552,0.869959,NO,212,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.904,-3.451,2.547,,,,B,1.59,-0.78,1.708,,42.42,BHO,-0.799667,0.100394,0.0031426,0.869959 kka2_1:8_L212T,kka2_1:8_212,Kka2,kka2_1:8,P00552,0.869959,NO,212,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.904,-3.451,2.547,,,,B,1.59,-0.78,1.708,,42.42,BHO,-0.799667,0.100394,0.0031426,0.869959 beta-lactamase_0_T178A,beta-lactamase_0_178,TEM-1,beta-lactamase_0,P62593,0.869979,NO,178,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-0.791,-2.853,2.062,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.0500837,0.000684366,0.869979 beta-lactamase_39_Y95K,beta-lactamase_39_95,TEM-1,beta-lactamase_39,P62593,0.870034,NO,95,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-1.715,-3.936,2.221,,0.122,,b,0.21,-0.37,2.341,,77.62,BHP,-2.16167,0.0495842,0.00479449,0.870034 beta-lactamase_0_R159Y,beta-lactamase_0_159,TEM-1,beta-lactamase_0,P62593,0.870045,NO,159,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-0.94,-4.035,3.095,,0.316,,B,1.2,-0.55,1.426,,64.34,PBH,-1.011,0.0500837,0.00108472,0.870045 beta-lactamase_L38G,beta-lactamase_38,TEM-1,beta-lactamase,P62593,0.870052,NO,38,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.343,-3.696,2.353,5.23728,0.088,H,A,1.75,0.2,1.986,,64.34,PHO,-1.78033,0.221079,0.00373244,0.870052 beta-lactamase_2500_A84C,beta-lactamase_2500_84,TEM-1,beta-lactamase_2500,P62593,0.870096,NO,84,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.651,-5.003,3.352,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.361275,0.00503822,0.870096 Pab1_I137M,Pab1_137,Pab1,Pab1,P04147,0.870104,NO,137,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.212,-3.847,2.635,,0.068,,B,0.77,0.35,,,,AHA,-1.314,0.175299,0.000342224,0.870104 beta-lactamase_0_E46T,beta-lactamase_0_46,TEM-1,beta-lactamase_0,P62593,0.870166,NO,46,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.94,-3.517,1.577,,0.021,E,B,1.04,0.14,30.306,30.306,59.44,HAH,-2.079,0.0500837,0.00427568,0.870166 beta-lactamase_0_S256E,beta-lactamase_0_256,TEM-1,beta-lactamase_0,P62593,0.870236,NO,256,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.0500837,0.00710634,0.870236 beta-lactamase_M115Q,beta-lactamase_115,TEM-1,beta-lactamase,P62593,0.870243,NO,115,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.389,-3.893,2.504,4.89743,0.019,E,B,1.3,0.08,1.236,,69.58,OHP,-1.25433,0.221079,0.0034337,0.870243 beta-lactamase_625_L223F,beta-lactamase_625_223,TEM-1,beta-lactamase_625,P62593,0.870265,NO,223,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.055,-2.724,1.669,,0.27,,B,0.55,0.09,1.633,,74.48,HHO,-1.35033,0.213352,0.00372793,0.870265 beta-lactamase_0_N168V,beta-lactamase_0_168,TEM-1,beta-lactamase_0,P62593,0.870274,NO,168,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-1.029,-3.632,2.603,,0.113,G,A,0.61,-0.4,0.881,,44.41,HPA,-1.13233,0.0500837,0.00288667,0.870274 beta-lactamase_V82W,beta-lactamase_82,TEM-1,beta-lactamase,P62593,0.870294,NO,82,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.325,-5.421,4.096,5.27777,0.267,H,A,0.96,0.08,1.379,,93.01,BHA,-1.28567,0.221079,0.00397046,0.870294 Pab1_I137F,Pab1_137,Pab1,Pab1,P04147,0.8703,NO,137,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.212,-3.434,2.222,,0.068,,B,0.77,0.35,,,,AHA,-1.314,0.175299,0.000342224,0.8703 kka2_1:8_R258Q,kka2_1:8_258,Kka2,kka2_1:8,P00552,0.870325,NO,258,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.626,-2.106,0.48,,0.316,H,A,0.16,-0.85,5.58,,53.03,HBH,-1.25933,0.100394,0.00983174,0.870325 kka2_1:8_R258Q,kka2_1:8_258,Kka2,kka2_1:8,P00552,0.870325,NO,258,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.626,-2.106,0.48,,0.316,H,A,0.16,-0.85,5.58,,53.03,HBH,-1.25933,0.100394,0.00983174,0.870325 PSD95pdz3_F325G,PSD95pdz3_325,PSD95pdz3,PSD95pdz3,P31016,0.870325,NO,325,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.524,-3.265,1.741,5.50654,,,,,12.7236,,,,OHP,-1.314,0.0758425,0.00102273,0.870325 kka2_1:1_A9S,kka2_1:1_9,Kka2,kka2_1:1,P00552,0.870328,NO,9,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.079,-2.471,0.392,,,,,,,0.383,,71.59,BHO,-2.253,0.520039,0.00273264,0.870328 beta-lactamase_0_L199Q,beta-lactamase_0_199,TEM-1,beta-lactamase_0,P62593,0.870458,NO,199,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-2.942,-3.22,0.278,,0.832,H,A,0.55,0.42,10.85,10.85,77.62,PHH,-2.32933,0.0500837,0.0048649,0.870458 kka2_1:8_A117C,kka2_1:8_117,Kka2,kka2_1:8,P00552,0.870471,NO,117,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.828,-4.504,3.676,,,H,A,1.04,-0.78,0.755,,45.83,HHA,-1.79333,0.100394,0.00282984,0.870471 kka2_1:8_A117C,kka2_1:8_117,Kka2,kka2_1:8,P00552,0.870471,NO,117,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.828,-4.504,3.676,,,H,A,1.04,-0.78,0.755,,45.83,HHA,-1.79333,0.100394,0.00282984,0.870471 kka2_1:4_V46W,kka2_1:4_46,Kka2,kka2_1:4,P00552,0.870495,NO,46,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-2.62,-5.568,2.948,,0.192,.,B,0.44,-1.12,9.564,,92.05,OHH,-1.88633,0.168804,0.00631301,0.870495 kka2_1:2_I115D,kka2_1:2_115,Kka2,kka2_1:2,P00552,0.870537,NO,115,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.606,-4.12,2.514,,0.105,H,A,0.48,-1.18,0.878,,65.53,PHH,-2.205,0.295029,0.00836567,0.870537 kka2_1:2_A110I,kka2_1:2_110,Kka2,kka2_1:2,P00552,0.870584,NO,110,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.064,-3.899,1.835,,0.175,H,A,0.46,-1.19,23.237,23.237,71.59,OHA,-1.91867,0.295029,0.00759851,0.870584 beta-lactamase_0_H156V,beta-lactamase_0_156,TEM-1,beta-lactamase_0,P62593,0.870629,NO,156,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-3.156,-3.735,0.579,,0.753,S,A,0.17,-0.6,23.367,23.367,77.62,ABH,-1.932,0.0500837,0.00468596,0.870629 beta-lactamase_39_D212I,beta-lactamase_39_212,TEM-1,beta-lactamase_39,P62593,0.870647,NO,212,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.624,-3.045,1.421,,0.037,,b,0.75,-0.58,10.748,10.748,74.48,HAB,-1.77667,0.0495842,0.00644302,0.870647 kka2_1:1_A87S,kka2_1:1_87,Kka2,kka2_1:1,P00552,0.870673,NO,87,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.917,-2.911,0.994,,1.039,S,L,0.46,1.57,20.738,20.738,65.53,AHO,-1.822,0.520039,0.00791281,0.870673 kka2_1:2_P128T,kka2_1:2_128,Kka2,kka2_1:2,P00552,0.870677,NO,128,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.922,-2.576,0.654,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.295029,0.00774689,0.870677 kka2_1:2_A110F,kka2_1:2_110,Kka2,kka2_1:2,P00552,0.870691,NO,110,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.064,-3.489,1.425,,0.175,H,A,0.46,-1.19,23.237,23.237,71.59,OHA,-1.91867,0.295029,0.00759851,0.870691 beta-lactamase_625_R91L,beta-lactamase_625_91,TEM-1,beta-lactamase_625,P62593,0.870758,NO,91,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.392,-3.471,2.079,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.213352,0.00380226,0.870758 kka2_1:8_R147G,kka2_1:8_147,Kka2,kka2_1:8,P00552,0.870788,NO,147,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.123,-3.428,2.305,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.100394,0.00549168,0.870788 kka2_1:8_R147G,kka2_1:8_147,Kka2,kka2_1:8,P00552,0.870788,NO,147,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.123,-3.428,2.305,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.100394,0.00549168,0.870788 kka2_1:2_F133W,kka2_1:2_133,Kka2,kka2_1:2,P00552,0.870799,NO,133,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-0.871,-4.449,3.578,,0.178,.,B,0.58,0.43,1.999,,42.42,OHA,-0.871667,0.295029,0.00182168,0.870799 beta-lactamase_0_M127F,beta-lactamase_0_127,TEM-1,beta-lactamase_0,P62593,0.870833,NO,127,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-2.251,-3.969,1.718,,0.312,S,A,0.55,0.32,9.35,9.35,72.73,PHP,-1.40433,0.0500837,0.00437927,0.870833 beta-lactamase_L135Q,beta-lactamase_135,TEM-1,beta-lactamase,P62593,0.870894,NO,135,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.002,-4.162,3.16,5.28497,0.117,H,A,1.07,-0.58,0.697,,43.71,PHH,-1.03767,0.221079,0.00244423,0.870894 Pab1_V198S,Pab1_198,Pab1,Pab1,P04147,0.870911,NO,198,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.113,-3.428,2.315,,0.008,E,B,0.61,0.91,,,,HHH,-1.32933,0.175299,0.000268557,0.870911 beta-lactamase_39_G236Y,beta-lactamase_39_236,TEM-1,beta-lactamase_39,P62593,0.870918,NO,236,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.784,-4.387,3.603,,0.241,,b,0.29,-0.59,1.883,,64.69,HOO,-1.025,0.0495842,0.00162372,0.870918 beta-lactamase_0_Q276W,beta-lactamase_0_276,TEM-1,beta-lactamase_0,P62593,0.870931,NO,276,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.0500837,0.0191712,0.870931 Ubiquitin_A46N,Ubiquitin_46,Uba1,Ubiquitin,P0CG48,0.870968,NO,46,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.77,-2.934,1.164,5.38761,0.398,T,L,2.34,-0.8,6.506,,51.09,HHO,-1.505,0.205827,0.000581142,0.870968 Ubiquitin_A46W,Ubiquitin_46,Uba1,Ubiquitin,P0CG48,0.870968,NO,46,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.77,-5.35,3.58,5.38761,0.398,T,L,2.34,-0.8,6.506,,51.09,HHO,-1.505,0.205827,0.000581142,0.870968 Ubiquitin_D24R,Ubiquitin_24,Uba1,Ubiquitin,P0CG48,0.870968,NO,24,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,,,,,,,,,,,,,HAP,,0.205827,0.0066591,0.870968 Ubiquitin_F45R,Ubiquitin_45,Uba1,Ubiquitin,P0CG48,0.870968,NO,45,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.322,-4.113,2.791,4.80693,0.26,E,B,1.62,-0.99,1.531,,53.87,HHH,-1.55267,0.205827,0.000470401,0.870968 Ubiquitin_G35V,Ubiquitin_35,Uba1,Ubiquitin,P0CG48,0.870968,NO,35,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.171,-2.694,1.523,4.96213,0.713,,L,,0.2,,,,AOH,-1.314,0.205827,0.000648878,0.870968 Ubiquitin_I13C,Ubiquitin_13,Uba1,Ubiquitin,P0CG48,0.870968,NO,13,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.554,-3.087,1.533,5.19411,0.038,E,B,,-0.2,,,,PHP,-1.48,0.205827,0.000716423,0.870968 Ubiquitin_I61F,Ubiquitin_61,Uba1,Ubiquitin,P0CG48,0.870968,NO,61,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.514,-3.912,2.398,5.19922,0.038,,B,1,-0.76,1.953,,24.53,PHP,-1.70833,0.205827,0.000738268,0.870968 Ubiquitin_L69C,Ubiquitin_69,Uba1,Ubiquitin,P0CG48,0.870968,NO,69,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.445,-4.899,3.454,4.75624,0.051,E,B,2.89,-0.94,7.106,,34.31,BHH,-1.72933,0.205827,0.000919136,0.870968 Ubiquitin_N60L,Ubiquitin_60,Uba1,Ubiquitin,P0CG48,0.870968,NO,60,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-1.775,-3.517,1.742,5.00332,0.775,T,L,,0.33,,,,HPH,-1.532,0.205827,0.000814061,0.870968 Ubiquitin_P37W,Ubiquitin_37,Uba1,Ubiquitin,P0CG48,0.870968,NO,37,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.275,-5.441,4.166,5.06918,0.323,,B,,-0.09,,,,HOO,-1.49,0.205827,0.000600764,0.870968 Ubiquitin_Q41G,Ubiquitin_41,Uba1,Ubiquitin,P0CG48,0.870968,NO,41,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-1.329,-2.464,1.135,4.9201,0.017,E,B,0.12,-0.98,0.812,,30.07,PPB,-1.55067,0.205827,0.000521668,0.870968 Ubiquitin_R74K,Ubiquitin_74,Uba1,Ubiquitin,P0CG48,0.870968,NO,74,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.739,-2.322,0.583,5.6462,0.838,T,A,0.98,3.15,9.119,9.119,34.31,HBO,-1.71767,0.205827,0.000894236,0.870968 Ubiquitin_T66M,Ubiquitin_66,Uba1,Ubiquitin,P0CG48,0.870968,NO,66,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.58,-4.577,2.997,5.02702,0.46,E,B,0.8,-0.81,28.36,28.36,39.71,PPH,-1.51667,0.205827,0.000598414,0.870968 Ubiquitin_T7G,Ubiquitin_7,Uba1,Ubiquitin,P0CG48,0.870968,NO,7,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.415,-3.414,1.999,4.954,0.094,E,B,0.43,-0.78,0.805,,21.31,BPH,-1.41033,0.205827,0.000647855,0.870968 Ubiquitin_T9H,Ubiquitin_9,Uba1,Ubiquitin,P0CG48,0.870968,NO,9,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.409,-4.635,3.226,5.24336,0.777,T,A,2.12,-0.12,2.705,,29.93,HPO,-1.50933,0.205827,0.000630716,0.870968 Ubiquitin_V5F,Ubiquitin_5,Uba1,Ubiquitin,P0CG48,0.870968,NO,5,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.576,-3.913,2.337,4.75677,,E,B,,-0.82,,,,HHB,-1.401,0.205827,0.000796998,0.870968 kka2_1:8_G55V,kka2_1:8_55,Kka2,kka2_1:8,P00552,0.870983,NO,55,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.625,-3.678,2.053,,0.517,S,b,0.29,1.19,8.881,,63.64,POH,-2.05967,0.100394,0.00667877,0.870983 kka2_1:8_G55V,kka2_1:8_55,Kka2,kka2_1:8,P00552,0.870983,NO,55,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.625,-3.678,2.053,,0.517,S,b,0.29,1.19,8.881,,63.64,POH,-2.05967,0.100394,0.00667877,0.870983 kka2_1:1_Q61R,kka2_1:1_61,Kka2,kka2_1:1,P00552,0.870996,NO,61,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.982,-2.952,-0.03,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.520039,0.00612092,0.870996 beta-lactamase_156_I45N,beta-lactamase_156_45,TEM-1,beta-lactamase_156,P62593,0.871004,NO,45,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-2.421,-3.135,0.714,,,E,B,0.48,-0.3,2.256,,77.62,HHA,-2.30267,0.111618,0.00452842,0.871004 beta-lactamase_V78L,beta-lactamase_78,TEM-1,beta-lactamase,P62593,0.87103,NO,78,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.459,-1.714,0.255,4.79197,,H,A,0.96,-0.47,1.132,,63.64,HHH,-1.17833,0.221079,0.00492501,0.87103 beta-lactamase_0_T263G,beta-lactamase_0_263,TEM-1,beta-lactamase_0,P62593,0.871061,NO,263,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.031,-3.618,1.587,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.0500837,0.0110582,0.871061 beta-lactamase_0_I229D,beta-lactamase_0_229,TEM-1,beta-lactamase_0,P62593,0.87111,NO,229,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.267,-3.973,2.706,,0.083,E,B,0.48,-0.76,1.69,,50,HHH,-1.58767,0.0500837,0.00477249,0.87111 gb1_L238I,gb1_238,gb1,gb1,P06654,0.871153,NO,238,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-2.98,-3.505,0.525,,,,,,,0.504,,45.54,PHB,-2.58633,0.177985,0.00205885,0.871153 beta-lactamase_R91S,beta-lactamase_91,TEM-1,beta-lactamase,P62593,0.871223,NO,91,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.392,-3.342,1.95,5.92536,0.444,,B,0.68,0.96,1.318,,50.35,OBB,-1.73367,0.221079,0.00380226,0.871223 Pab1_N132E,Pab1_132,Pab1,Pab1,P04147,0.871254,NO,132,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-1.079,-3.032,1.953,,0.412,S,l,,0.9,,,,BPH,-1.067,0.175299,0.000347671,0.871254 kka2_1:8_A222C,kka2_1:8_222,Kka2,kka2_1:8,P00552,0.871372,NO,222,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.725,-4.44,3.715,,,H,A,1.04,-1.21,,,,HHH,-1.10833,0.100394,0.00207657,0.871372 kka2_1:8_A222C,kka2_1:8_222,Kka2,kka2_1:8,P00552,0.871372,NO,222,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.725,-4.44,3.715,,,H,A,1.04,-1.21,,,,HHH,-1.10833,0.100394,0.00207657,0.871372 beta-lactamase_2500_F149V,beta-lactamase_2500_149,TEM-1,beta-lactamase_2500,P62593,0.871378,NO,149,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.299,-3.45,2.151,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.361275,0.00418462,0.871378 kka2_1:4_V97A,kka2_1:4_97,Kka2,kka2_1:4,P00552,0.87147,NO,97,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.453,-2.616,1.163,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.168804,0.00737869,0.87147 beta-lactamase_625_Y103Q,beta-lactamase_625_103,TEM-1,beta-lactamase_625,P62593,0.871527,NO,103,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-1.33,-2.924,1.594,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.213352,0.00443048,0.871527 beta-lactamase_2500_R92W,beta-lactamase_2500_92,TEM-1,beta-lactamase_2500,P62593,0.871534,NO,92,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.718,-5.477,3.759,,0.479,E,B,1.2,1.36,3.069,,65.38,BBH,-1.50367,0.361275,0.00429626,0.871534 beta-lactamase_A170M,beta-lactamase_170,TEM-1,beta-lactamase,P62593,0.871564,NO,170,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.237,-4.595,3.358,5.19261,0.126,,L,2.34,-0.35,2.427,,64.69,AHH,-1.63267,0.221079,0.00431903,0.871564 beta-lactamase_C75I,beta-lactamase_75,TEM-1,beta-lactamase,P62593,0.871564,NO,75,C,I,CI,Special,Hydrophobic,5.07,6.02,0.95,198,121,131,10,108.5,166.7,58.2,-1.245,-3.708,2.463,4.88171,,H,A,0.25,-0.87,0.876,,50,HOO,-1.24333,0.221079,0.0034616,0.871564 beta-lactamase_D113I,beta-lactamase_113,TEM-1,beta-lactamase,P62593,0.871564,NO,113,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.829,-4.028,2.199,6.04499,0.665,T,A,0.23,0.91,21.104,21.104,73.08,PAO,-1.703,0.221079,0.00474112,0.871564 beta-lactamase_D113W,beta-lactamase_113,TEM-1,beta-lactamase,P62593,0.871564,NO,113,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.829,-5.545,3.716,6.04499,0.665,T,A,0.23,0.91,21.104,21.104,73.08,PAO,-1.703,0.221079,0.00474112,0.871564 beta-lactamase_E108C,beta-lactamase_108,TEM-1,beta-lactamase,P62593,0.871564,NO,108,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.46,-5.208,3.748,5.52079,0.572,G,A,0.52,1.87,1.973,,72.73,PAB,-1.437,0.221079,0.00413372,0.871564 beta-lactamase_E26R,beta-lactamase_26,TEM-1,beta-lactamase,P62593,0.871564,NO,26,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.454,-2.433,-0.021,,0.54,H,A,1.04,0.98,,,93.01,OAP,-1.96167,0.221079,0.00297948,0.871564 beta-lactamase_E270W,beta-lactamase_270,TEM-1,beta-lactamase,P62593,0.871564,NO,270,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.723,-5.474,3.751,5.33196,0.422,H,A,0.52,1.15,1.745,,64.34,AAB,-1.70933,0.221079,0.00767762,0.871564 beta-lactamase_E62C,beta-lactamase_62,TEM-1,beta-lactamase,P62593,0.871564,NO,62,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.193,-5.228,4.035,5.93066,0.342,S,B,1.52,-0.3,3.139,,73.08,AAB,-1.417,0.221079,0.00264802,0.871564 beta-lactamase_E62L,beta-lactamase_62,TEM-1,beta-lactamase,P62593,0.871564,NO,62,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.193,-3.66,2.467,5.93066,0.342,S,B,1.52,-0.3,3.139,,73.08,AAB,-1.417,0.221079,0.00264802,0.871564 beta-lactamase_F149Q,beta-lactamase_149,TEM-1,beta-lactamase,P62593,0.871564,NO,149,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.299,-4.204,2.905,5.54789,0.195,H,A,1.1,0.11,1.863,,63.99,HHH,-1.46067,0.221079,0.00418462,0.871564 beta-lactamase_F22D,beta-lactamase_22,TEM-1,beta-lactamase,P62593,0.871564,NO,22,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-2.676,-2.634,-0.042,,,,,,,1.616,,73.08,HHH,-2.03233,0.221079,0.00262842,0.871564 beta-lactamase_L192Y,beta-lactamase_192,TEM-1,beta-lactamase,P62593,0.871564,NO,192,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.254,-3.913,2.659,5.68899,0.095,H,A,1.3,0.35,1.756,,60.14,HHP,-1.41833,0.221079,0.00558728,0.871564 beta-lactamase_L28G,beta-lactamase_28,TEM-1,beta-lactamase,P62593,0.871564,NO,28,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.579,-3.602,2.023,5.42969,0.277,H,A,0.07,-0.16,19.748,19.748,93.01,PHH,-2.11333,0.221079,0.00359321,0.871564 beta-lactamase_P217F,beta-lactamase_217,TEM-1,beta-lactamase,P62593,0.871564,NO,217,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-2.062,-4.432,2.37,5.19872,0.496,I,A,0.99,-0.33,0.431,,74.48,OOH,-1.64333,0.221079,0.00463211,0.871564 beta-lactamase_R159M,beta-lactamase_159,TEM-1,beta-lactamase,P62593,0.871564,NO,159,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-0.94,-4.529,3.589,5.64971,0.316,,B,0.68,-0.55,1.172,,64.34,PBH,-1.011,0.221079,0.00108472,0.871564 beta-lactamase_R176Y,beta-lactamase_176,TEM-1,beta-lactamase,P62593,0.871564,NO,176,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-0.863,-4.162,3.299,5.61264,0.385,T,B,0.68,-0.63,,,,ABA,-1.38867,0.221079,0.00105554,0.871564 beta-lactamase_R63M,beta-lactamase_63,TEM-1,beta-lactamase,P62593,0.871564,NO,63,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-0.943,-4.402,3.459,5.49979,0.218,,B,0.45,-0.31,0.677,,44.06,ABH,-0.992333,0.221079,0.00126938,0.871564 beta-lactamase_S281W,beta-lactamase_281,TEM-1,beta-lactamase,P62593,0.871564,NO,281,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.247,-5.379,3.132,4.73591,0.128,H,A,0.25,-0.26,2.144,,77.62,HPH,-1.847,0.221079,0.0406482,0.871564 beta-lactamase_S51R,beta-lactamase_51,TEM-1,beta-lactamase,P62593,0.871564,NO,51,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.526,-2.956,1.43,5.06164,0.496,T,A,0.25,0.26,1.699,,72.73,PPO,-1.88467,0.221079,0.00504821,0.871564 beta-lactamase_T139Y,beta-lactamase_139,TEM-1,beta-lactamase,P62593,0.871564,NO,139,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.901,-4.252,2.351,5.69095,0.216,H,A,0.3,0.39,2.256,,77.62,PPH,-2.04667,0.221079,0.00441837,0.871564 beta-lactamase_T147H,beta-lactamase_147,TEM-1,beta-lactamase,P62593,0.871564,NO,147,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.149,-4.643,3.494,5.37474,0.281,H,A,0.8,-0.68,2.838,,64.34,HPH,-1.456,0.221079,0.00226017,0.871564 beta-lactamase_V101G,beta-lactamase_101,TEM-1,beta-lactamase,P62593,0.871564,NO,101,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.295,-3.721,2.426,5.49045,0.342,,B,0.96,0,1.675,,73.08,HHA,-1.54367,0.221079,0.00374492,0.871564 beta-lactamase_V106F,beta-lactamase_106,TEM-1,beta-lactamase,P62593,0.871564,NO,106,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.218,-2.585,1.367,5.23115,0.258,T,A,0.96,0.24,1.188,,72.73,OHP,-1.04933,0.221079,0.00304168,0.871564 beta-lactamase_V106W,beta-lactamase_106,TEM-1,beta-lactamase,P62593,0.871564,NO,106,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.218,-5.22,4.002,5.23115,0.258,T,A,0.96,0.24,1.188,,72.73,OHP,-1.04933,0.221079,0.00304168,0.871564 beta-lactamase_V78T,beta-lactamase_78,TEM-1,beta-lactamase,P62593,0.871564,NO,78,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.459,-3.492,2.033,4.79197,,H,A,0.96,-0.47,1.132,,63.64,HHH,-1.17833,0.221079,0.00492501,0.871564 beta-lactamase_X287I,beta-lactamase_287,TEM-1,beta-lactamase,P62593,0.871564,NO,287,X,I,XI,Stop,Hydrophobic,5.71,6.02,0.31,,132.5,131,-1,141.9,166.7,24.8,,,,,,,,,,,,,HXO,-1.111,0.221079,,0.871564 beta-lactamase_Y103P,beta-lactamase_103,TEM-1,beta-lactamase,P62593,0.871564,NO,103,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-1.33,-4.138,2.808,5.71734,0.613,S,l,2.55,1.21,5.721,,63.29,AHP,-1.48767,0.221079,0.00443048,0.871564 kka2_1:2_Y244L,kka2_1:2_244,Kka2,kka2_1:2,P00552,0.871569,NO,244,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-0.775,-3.161,2.386,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.295029,0.00453187,0.871569 beta-lactamase_0_T178G,beta-lactamase_0_178,TEM-1,beta-lactamase_0,P62593,0.87161,NO,178,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-0.791,-3.358,2.567,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.0500837,0.000684366,0.87161 kka2_1:8_I115C,kka2_1:8_115,Kka2,kka2_1:8,P00552,0.871639,NO,115,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.606,-4.846,3.24,,0.105,H,A,1.52,-1.18,4.064,,65.53,PHH,-2.205,0.100394,0.00836567,0.871639 kka2_1:8_I115C,kka2_1:8_115,Kka2,kka2_1:8,P00552,0.871639,NO,115,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.606,-4.846,3.24,,0.105,H,A,1.52,-1.18,4.064,,65.53,PHH,-2.205,0.100394,0.00836567,0.871639 beta-lactamase_0_N134Y,beta-lactamase_0_134,TEM-1,beta-lactamase_0,P62593,0.871658,NO,134,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-0.879,-4.188,3.309,,0.138,H,A,0.61,-0.6,3.776,,53.15,HPH,-1.02233,0.0500837,0.000644786,0.871658 beta-lactamase_0_F64M,beta-lactamase_0_64,TEM-1,beta-lactamase_0,P62593,0.871694,NO,64,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-0.841,-4.255,3.414,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.0500837,0.000947691,0.871694 beta-lactamase_0_P65H,beta-lactamase_0_65,TEM-1,beta-lactamase_0,P62593,0.871735,NO,65,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.894,-4.735,3.841,,0.098,E,B,0.52,-0.62,0.663,,40.56,HOH,-1.03233,0.0500837,0.00152776,0.871735 beta-lactamase_0_R81M,beta-lactamase_0_81,TEM-1,beta-lactamase_0,P62593,0.871778,NO,81,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.466,-4.579,3.113,,0.218,H,A,1.2,1.66,0.332,,50,PBH,-1.60667,0.0500837,0.00499763,0.871778 Pab1_G126E,Pab1_126,Pab1,Pab1,P04147,0.871811,NO,126,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.985,-3.475,2.49,,0.011,T,A,0.46,-0.07,2.349,,80.42,OOP,-1.032,0.175299,0.00109814,0.871811 kka2_1:1_A25S,kka2_1:1_25,Kka2,kka2_1:1,P00552,0.871832,NO,25,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.496,-2.739,0.243,,0.427,E,B,0.46,-0.47,6.872,6.872,65.53,HHP,-2.15167,0.520039,0.00595636,0.871832 beta-lactamase_0_T193R,beta-lactamase_0_193,TEM-1,beta-lactamase_0,P62593,0.871852,NO,193,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.914,-4.014,2.1,,0.439,H,a,0.22,0.33,11.546,11.546,63.99,HPO,-1.52133,0.0500837,0.00482669,0.871852 Pab1_A179D,Pab1_179,Pab1,Pab1,P04147,0.871879,NO,179,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.013,-3.511,2.498,,0.078,H,A,0.61,0.5,,,,HHB,-1.51233,0.175299,0.000291703,0.871879 beta-lactamase_0_L74F,beta-lactamase_0_74,TEM-1,beta-lactamase_0,P62593,0.871958,NO,74,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.296,-3.848,2.552,,,H,A,0.55,-0.91,1.46,,50,HHO,-1.34933,0.0500837,0.00493255,0.871958 kka2_1:2_E235K,kka2_1:2_235,Kka2,kka2_1:2,P00552,0.871968,NO,235,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.955,-2.949,0.994,,0.631,H,A,1.04,0.12,26.048,26.048,65.53,OAH,-2.07267,0.295029,0.0102806,0.871968 beta-lactamase_156_D161K,beta-lactamase_156_161,TEM-1,beta-lactamase_156,P62593,0.871983,NO,161,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.891,-3.426,2.535,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.111618,0.000897697,0.871983 Pab1_T145H,Pab1_145,Pab1,Pab1,P04147,0.871987,NO,145,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.067,-4.497,3.43,,0.237,H,A,0.3,0.69,,,,APH,-1.135,0.175299,0.000331088,0.871987 beta-lactamase_0_I244F,beta-lactamase_0_244,TEM-1,beta-lactamase_0,P62593,0.872006,NO,244,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.555,-3.842,2.287,,,E,B,0.48,-0.84,1.241,,77.62,OHH,-1.385,0.0500837,0.00605379,0.872006 beta-lactamase_0_R91G,beta-lactamase_0_91,TEM-1,beta-lactamase_0,P62593,0.872124,NO,91,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.392,-3.437,2.045,,0.444,,B,1.2,0.96,4.557,,50.35,OBB,-1.73367,0.0500837,0.00380226,0.872124 kka2_1:8_V153H,kka2_1:8_153,Kka2,kka2_1:8,P00552,0.872125,NO,153,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.092,-4.991,3.899,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.100394,0.00501119,0.872125 kka2_1:8_V153H,kka2_1:8_153,Kka2,kka2_1:8,P00552,0.872125,NO,153,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.092,-4.991,3.899,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.100394,0.00501119,0.872125 kka2_1:8_N200T,kka2_1:8_200,Kka2,kka2_1:8,P00552,0.872173,NO,200,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-2.446,-3.096,0.65,,0.756,T,L,0.43,-0.08,2.528,,64.39,APO,-2.08,0.100394,0.00838549,0.872173 kka2_1:8_N200T,kka2_1:8_200,Kka2,kka2_1:8,P00552,0.872173,NO,200,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-2.446,-3.096,0.65,,0.756,T,L,0.43,-0.08,2.528,,64.39,APO,-2.08,0.100394,0.00838549,0.872173 kka2_1:4_E161K,kka2_1:4_161,Kka2,kka2_1:4,P00552,0.872195,NO,161,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.581,-3.478,1.897,,0.829,G,A,1.52,2.24,1.612,,92.05,AAB,-1.861,0.168804,0.00760103,0.872195 beta-lactamase_V214S,beta-lactamase_214,TEM-1,beta-lactamase,P62593,0.872202,NO,214,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.299,-3.408,2.109,5.74008,0.375,S,A,1.19,-0.44,1.899,,74.48,BHH,-1.53733,0.221079,0.00628442,0.872202 gb1_G264E,gb1_264,gb1,gb1,P06654,0.872225,NO,264,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.833,-3.5,1.667,,,,,,,0.864,,44.87,POH,-1.61267,0.177985,0.0049716,0.872225 gb1_T242N,gb1_242,gb1,gb1,P06654,0.872225,NO,242,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.245,-3.183,1.938,,,,,,,,,,APP,-1.444,0.177985,0.00243886,0.872225 gb1_T281G,gb1_281,gb1,gb1,P06654,0.872225,NO,281,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.828,-3.021,1.193,,,,,,,1.038,,35.71,HPA,-1.63667,0.177985,0.00284418,0.872225 beta-lactamase_0_I45E,beta-lactamase_0_45,TEM-1,beta-lactamase_0,P62593,0.872239,NO,45,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-2.421,-3.737,1.316,,,E,B,0.48,-0.3,1.375,,77.62,HHA,-2.30267,0.0500837,0.00452842,0.872239 kka2_1:8_S104Y,kka2_1:8_104,Kka2,kka2_1:8,P00552,0.872253,NO,104,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.436,-4.278,2.842,,0.536,T,A,0.27,-1.11,1.689,,63.64,HPP,-1.91433,0.100394,0.00555207,0.872253 kka2_1:8_S104Y,kka2_1:8_104,Kka2,kka2_1:8,P00552,0.872253,NO,104,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.436,-4.278,2.842,,0.536,T,A,0.27,-1.11,1.689,,63.64,HPP,-1.91433,0.100394,0.00555207,0.872253 beta-lactamase_0_L218E,beta-lactamase_0_218,TEM-1,beta-lactamase_0,P62593,0.872272,NO,218,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.391,-3.611,2.22,,,I,b,0.55,-0.53,28.707,28.707,74.48,OHH,-1.58867,0.0500837,0.00618274,0.872272 beta-lactamase_0_G240S,beta-lactamase_0_240,TEM-1,beta-lactamase_0,P62593,0.872278,NO,240,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.537,-2.475,0.938,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.0500837,0.00591201,0.872278 beta-lactamase_0_L79Y,beta-lactamase_0_79,TEM-1,beta-lactamase_0,P62593,0.87228,NO,79,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.842,-3.963,3.121,,0.007,H,A,0.55,-0.16,5.053,,50.35,HHP,-1.44333,0.0500837,0.000947397,0.87228 Pab1_L186F,Pab1_186,Pab1,Pab1,P04147,0.872282,NO,186,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.783,-3.65,1.867,,,,,,,,,,HHP,-1.56967,0.175299,0.00154968,0.872282 kka2_1:2_L126V,kka2_1:2_126,Kka2,kka2_1:2,P00552,0.872294,NO,126,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.246,-1.955,0.709,,0.285,S,B,0.55,0.12,1.392,,51.89,PHA,-1.744,0.295029,0.0066485,0.872294 beta-lactamase_0_G43N,beta-lactamase_0_43,TEM-1,beta-lactamase_0,P62593,0.872345,NO,43,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.62,-3.448,2.828,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.0500837,0.00120151,0.872345 Pab1_L133C,Pab1_133,Pab1,Pab1,P04147,0.872387,NO,133,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.039,-4.454,3.415,,0.015,,B,1.75,1.03,,,,PHB,-1.22,0.175299,0.000345939,0.872387 beta-lactamase_L47Q,beta-lactamase_47,TEM-1,beta-lactamase,P62593,0.872444,NO,47,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.876,-3.17,1.294,5.27297,0.007,E,B,1.07,0.2,1.244,,67.83,AHA,-1.639,0.221079,0.00439844,0.872444 beta-lactamase_0_M184S,beta-lactamase_0_184,TEM-1,beta-lactamase_0,P62593,0.872454,NO,184,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.593,-3.463,1.87,,,H,A,0.55,-0.87,13.292,13.292,62.94,HHH,-1.41,0.0500837,0.00356019,0.872454 kka2_1:4_W24C,kka2_1:4_24,Kka2,kka2_1:4,P00552,0.87246,NO,24,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-1.779,-3.129,1.35,,0.477,E,B,1.51,-0.21,2.666,,56.06,AHH,-2.24467,0.168804,0.00631564,0.87246 beta-lactamase_0_N130R,beta-lactamase_0_130,TEM-1,beta-lactamase_0,P62593,0.872479,NO,130,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-0.798,-3.483,2.685,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.0500837,0.000683376,0.872479 kka2_1:2_L259C,kka2_1:2_259,Kka2,kka2_1:2,P00552,0.87257,NO,259,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.088,-4.727,3.639,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.295029,0.0206964,0.87257 beta-lactamase_0_T263N,beta-lactamase_0_263,TEM-1,beta-lactamase_0,P62593,0.872577,NO,263,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.0500837,0.0110582,0.872577 beta-lactamase_E46D,beta-lactamase_46,TEM-1,beta-lactamase,P62593,0.872674,NO,46,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.94,-3.652,1.712,5.36461,0.021,E,B,1.51,0.14,0.373,,59.44,HAH,-2.079,0.221079,0.00427568,0.872674 beta-lactamase_625_P250Y,beta-lactamase_625_250,TEM-1,beta-lactamase_625,P62593,0.8727,NO,250,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.213352,0.00550899,0.8727 beta-lactamase_2500_A215S,beta-lactamase_2500_215,TEM-1,beta-lactamase_2500,P62593,0.872708,NO,215,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.503,-2.232,0.729,,,,a,0.46,-0.93,3.516,,74.48,HHO,-1.42633,0.361275,0.00544007,0.872708 kka2_1:8_R147L,kka2_1:8_147,Kka2,kka2_1:8,P00552,0.87273,NO,147,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.123,-3.547,2.424,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.100394,0.00549168,0.87273 kka2_1:8_R147L,kka2_1:8_147,Kka2,kka2_1:8,P00552,0.87273,NO,147,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.123,-3.547,2.424,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.100394,0.00549168,0.87273 PSD95pdz3_E373T,PSD95pdz3_373,PSD95pdz3,PSD95pdz3,P31016,0.872731,NO,373,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.404,-3.103,1.699,5.79743,,,,,27.9833,,,,BAP,-1.57667,0.0758425,0.000387698,0.872731 beta-lactamase_0_N168F,beta-lactamase_0_168,TEM-1,beta-lactamase_0,P62593,0.872738,NO,168,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-1.029,-4.27,3.241,,0.113,G,A,0.61,-0.4,0.881,,44.41,HPA,-1.13233,0.0500837,0.00288667,0.872738 beta-lactamase_156_P224W,beta-lactamase_156_224,TEM-1,beta-lactamase_156,P62593,0.87276,NO,224,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.893,-5.546,4.653,,0.383,,B,0.52,-0.3,0.383,,74.48,HOH,-1.26433,0.111618,0.00189564,0.87276 kka2_1:2_P249T,kka2_1:2_249,Kka2,kka2_1:2,P00552,0.872808,NO,249,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.867,-2.639,0.772,,0.406,.,B,0.52,-0.01,0.76,,92.05,HOA,-1.66867,0.295029,0.011045,0.872808 kka2_1:4_L57T,kka2_1:4_57,Kka2,kka2_1:4,P00552,0.872823,NO,57,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.898,-3.729,1.831,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.168804,0.00723769,0.872823 beta-lactamase_M153R,beta-lactamase_153,TEM-1,beta-lactamase,P62593,0.872867,NO,153,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-3.193,-4.075,0.882,5.46509,0.14,T,A,1.07,-0.11,2.061,,77.62,PHO,-2.25767,0.221079,0.00509109,0.872867 beta-lactamase_0_T139N,beta-lactamase_0_139,TEM-1,beta-lactamase_0,P62593,0.87287,NO,139,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.901,-3.686,1.785,,0.216,H,A,0.22,0.39,0.421,,77.62,PPH,-2.04667,0.0500837,0.00441837,0.87287 beta-lactamase_0_R162I,beta-lactamase_0_162,TEM-1,beta-lactamase_0,P62593,0.872909,NO,162,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.016,-3.867,2.851,,0.124,S,B,1.2,-0.37,1.026,,64.69,ABH,-1.25,0.0500837,0.000561334,0.872909 beta-lactamase_T27S,beta-lactamase_27,TEM-1,beta-lactamase,P62593,0.87296,NO,27,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.905,-2.606,0.701,5.39752,0.007,H,A,0.69,-0.37,0.745,,93.01,APH,-1.97933,0.221079,0.00306559,0.87296 beta-lactamase_0_T269K,beta-lactamase_0_269,TEM-1,beta-lactamase_0,P62593,0.873004,NO,269,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.0500837,0.00950944,0.873004 Pab1_I152L,Pab1_152,Pab1,Pab1,P04147,0.873022,NO,152,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.345,-2.419,1.074,,0.165,E,B,1.23,-0.71,1.288,,71.4,AHH,-1.59433,0.175299,0.000740963,0.873022 Pab1_Y143V,Pab1_143,Pab1,Pab1,P04147,0.873031,NO,143,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-1.961,-3.459,1.498,,0.409,H,A,,0.3,,,,HHA,-1.39633,0.175299,0.00160364,0.873031 kka2_1:8_A71H,kka2_1:8_71,Kka2,kka2_1:8,P00552,0.873096,NO,71,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.824,-3.209,1.385,,0.553,H,A,0.46,0.08,18.64,18.64,64.39,HHP,-1.74033,0.100394,0.00727707,0.873096 kka2_1:8_A71H,kka2_1:8_71,Kka2,kka2_1:8,P00552,0.873096,NO,71,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.824,-3.209,1.385,,0.553,H,A,0.46,0.08,18.64,18.64,64.39,HHP,-1.74033,0.100394,0.00727707,0.873096 beta-lactamase_0_L38A,beta-lactamase_0_38,TEM-1,beta-lactamase_0,P62593,0.873103,NO,38,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.343,-3.151,1.808,,0.088,H,A,0.55,0.2,13.556,13.556,64.34,PHO,-1.78033,0.0500837,0.00373244,0.873103 beta-lactamase_0_L218Q,beta-lactamase_0_218,TEM-1,beta-lactamase_0,P62593,0.873117,NO,218,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.391,-3.953,2.562,,,I,b,0.55,-0.53,28.707,28.707,74.48,OHH,-1.58867,0.0500837,0.00618274,0.873117 Pab1_G188L,Pab1_188,Pab1,Pab1,P04147,0.873131,NO,188,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.809,-3.625,2.816,,0.379,E,g,,2.18,,,,POH,-1.14633,0.175299,0.000280911,0.873131 beta-lactamase_0_W208H,beta-lactamase_0_208,TEM-1,beta-lactamase_0,P62593,0.873146,NO,208,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-0.818,-4.68,3.862,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.0500837,0.00126609,0.873146 beta-lactamase_R63P,beta-lactamase_63,TEM-1,beta-lactamase,P62593,0.873193,NO,63,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-0.943,-3.929,2.986,5.49979,0.218,,B,0.45,-0.31,0.677,,44.06,ABH,-0.992333,0.221079,0.00126938,0.873193 beta-lactamase_2500_L74M,beta-lactamase_2500_74,TEM-1,beta-lactamase_2500,P62593,0.873203,NO,74,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.296,-2.987,1.691,,,H,A,0.55,-0.91,0.746,,50,HHO,-1.34933,0.361275,0.00493255,0.873203 beta-lactamase_M127D,beta-lactamase_127,TEM-1,beta-lactamase,P62593,0.873249,NO,127,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-2.251,-3.966,1.715,5.40552,0.312,S,A,1.07,0.32,1.671,,72.73,PHP,-1.40433,0.221079,0.00437927,0.873249 gb1_G264Q,gb1_264,gb1,gb1,P06654,0.873289,NO,264,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.833,-3.93,2.097,,,,,,,0.864,,44.87,POH,-1.61267,0.177985,0.0049716,0.873289 kka2_1:8_G210C,kka2_1:8_210,Kka2,kka2_1:8,P00552,0.873359,NO,210,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.095,-2.875,1.78,,0.103,T,A,0.75,-0.62,2.687,,50,OOB,-0.966667,0.100394,0.00598378,0.873359 kka2_1:8_G210C,kka2_1:8_210,Kka2,kka2_1:8,P00552,0.873359,NO,210,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.095,-2.875,1.78,,0.103,T,A,0.75,-0.62,2.687,,50,OOB,-0.966667,0.100394,0.00598378,0.873359 kka2_1:8_V186L,kka2_1:8_186,Kka2,kka2_1:8,P00552,0.873359,NO,186,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.011,-2.323,1.312,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.100394,0.00409703,0.873359 kka2_1:8_V186L,kka2_1:8_186,Kka2,kka2_1:8,P00552,0.873359,NO,186,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.011,-2.323,1.312,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.100394,0.00409703,0.873359 beta-lactamase_G85T,beta-lactamase_85,TEM-1,beta-lactamase,P62593,0.873391,NO,85,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.011,-3.637,2.626,5.58951,0.805,T,l,0.23,1.7,1.468,,63.64,HOP,-1.68733,0.221079,0.00252173,0.873391 beta-lactamase_625_E56Y,beta-lactamase_625_56,TEM-1,beta-lactamase_625,P62593,0.873396,NO,56,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.043,-4.216,2.173,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.213352,0.00238534,0.873396 beta-lactamase_V214N,beta-lactamase_214,TEM-1,beta-lactamase,P62593,0.873443,NO,214,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.299,-3.962,2.663,5.74008,0.375,S,A,1.19,-0.44,1.899,,74.48,BHH,-1.53733,0.221079,0.00628442,0.873443 beta-lactamase_0_N98S,beta-lactamase_0_98,TEM-1,beta-lactamase_0,P62593,0.87345,NO,98,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-2.973,-2.34,-0.633,,0.963,G,A,0.61,1.35,14.853,14.853,77.62,PPA,-2.07867,0.0500837,0.00505389,0.87345 beta-lactamase_I3A,beta-lactamase_3,TEM-1,beta-lactamase,P62593,0.873461,NO,3,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-2.143,-2.247,0.104,,,,,,,3.946,,93.01,PHP,-2.21633,0.221079,0.00349304,0.873461 beta-lactamase_P20T,beta-lactamase_20,TEM-1,beta-lactamase,P62593,0.873461,NO,20,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.74,-2.522,0.782,,,,,,,0.368,,67.83,HOH,-1.765,0.221079,0.00235322,0.873461 beta-lactamase_G251W,beta-lactamase_251,TEM-1,beta-lactamase,P62593,0.873489,NO,251,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.907,-5.493,3.586,5.33865,0.506,T,l,0.73,0.17,10.663,,65.38,AOB,-2.06067,0.221079,0.00733416,0.873489 kka2_1:2_C192S,kka2_1:2_192,Kka2,kka2_1:2,P00552,0.873515,NO,192,C,S,CS,Special,Polar,5.07,5.68,0.61,112,121,105,-16,108.5,89,-19.5,-1.067,-2.445,1.378,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.295029,0.00485428,0.873515 beta-lactamase_L111D,beta-lactamase_111,TEM-1,beta-lactamase,P62593,0.873518,NO,111,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.76,-3.995,2.235,5.8705,0.328,T,A,0.84,0.93,3.836,,64.34,BHP,-1.884,0.221079,0.00480671,0.873518 kka2_1:8_R140W,kka2_1:8_140,Kka2,kka2_1:8,P00552,0.873528,NO,140,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.351,-5.43,4.079,,0.12,H,A,0.16,0.2,2.874,,53.03,BBH,-1.885,0.100394,0.00430167,0.873528 kka2_1:8_R140W,kka2_1:8_140,Kka2,kka2_1:8,P00552,0.873528,NO,140,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.351,-5.43,4.079,,0.12,H,A,0.16,0.2,2.874,,53.03,BBH,-1.885,0.100394,0.00430167,0.873528 E1_Ubiquitin_K48D,E1_Ubiquitin_48,Uba1,E1_Ubiquitin,P0CG63,0.873563,NO,48,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.219,-3.128,1.909,,0.132,E,B,,-0.28,,,,OBO,-1.109,0.18783,0.00100363,0.873563 beta-lactamase_P181V,beta-lactamase_181,TEM-1,beta-lactamase,P62593,0.873568,NO,181,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.813,-3.492,2.679,5.14752,,H,A,1.1,-1.14,1.357,,61.54,HOH,-1.795,0.221079,0.000703122,0.873568 beta-lactamase_C75S,beta-lactamase_75,TEM-1,beta-lactamase,P62593,0.8736,NO,75,C,S,CS,Special,Polar,5.07,5.68,0.61,112,121,105,-16,108.5,89,-19.5,-1.245,-2.597,1.352,4.88171,,H,A,0.25,-0.87,0.876,,50,HOO,-1.24333,0.221079,0.0034616,0.8736 beta-lactamase_0_M180V,beta-lactamase_0_180,TEM-1,beta-lactamase_0,P62593,0.873631,NO,180,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-2.795,-3.273,0.478,,0.242,,B,0.55,-0.94,2.892,,77.62,PHO,-1.56433,0.0500837,0.00552048,0.873631 beta-lactamase_0_W227Q,beta-lactamase_0_227,TEM-1,beta-lactamase_0,P62593,0.873666,NO,227,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-0.982,-4.194,3.212,,0.272,,B,0.47,-0.29,3.782,,74.48,OHH,-1.595,0.0500837,0.00226019,0.873666 PSD95pdz3_E373G,PSD95pdz3_373,PSD95pdz3,PSD95pdz3,P31016,0.873691,NO,373,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.404,-3.04,1.636,5.79743,,,,,27.9833,,,,BAP,-1.57667,0.0758425,0.000387698,0.873691 WW_domain_Q200D,WW_domain_200,Yap65,WW_domain,P46937,0.873728,NO,200,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-1.599,-3.266,1.667,5.37476,,,,,,1.9,,70.04,HPA,-1.484,0.153962,0.00300397,0.873728 kka2_1:2_G21C,kka2_1:2_21,Kka2,kka2_1:2,P00552,0.873768,NO,21,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.368,-5.139,3.771,,0.586,T,l,0.29,-0.75,2.026,,71.59,HOH,-2.10167,0.295029,0.00709648,0.873768 beta-lactamase_2500_I45T,beta-lactamase_2500_45,TEM-1,beta-lactamase_2500,P62593,0.873818,NO,45,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-2.421,-2.537,0.116,,,E,B,0.48,-0.3,3.793,,77.62,HHA,-2.30267,0.361275,0.00452842,0.873818 beta-lactamase_625_R41C,beta-lactamase_625_41,TEM-1,beta-lactamase_625,P62593,0.87382,NO,41,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-0.942,-5.05,4.108,,0.321,E,B,1.2,-0.07,1.186,,65.03,HBH,-1.30267,0.213352,0.00123327,0.87382 kka2_1:2_A41E,kka2_1:2_41,Kka2,kka2_1:2,P00552,0.873902,NO,41,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.879,-3.093,1.214,,0.184,.,B,0.46,-0.96,24.451,24.451,64.39,PHP,-2.477,0.295029,0.00543332,0.873902 kka2_1:4_G88R,kka2_1:4_88,Kka2,kka2_1:4,P00552,0.873986,NO,88,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.689,-3.209,1.52,,0.54,S,l,0.29,1.51,7.899,,65.53,HOB,-1.718,0.168804,0.00685559,0.873986 hsp90_G584M,hsp90_584,hsp90,hsp90,P02829,0.873989,NO,584,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-2.511,-3.858,0,5.20094,0.414,S,b,0.84,0.33,,,,HOH,-3.32733,0.368192,0.000222939,0.873989 beta-lactamase_39_S80P,beta-lactamase_39_80,TEM-1,beta-lactamase_39,P62593,0.874006,NO,80,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.029,-3.939,1.91,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.0495842,0.00565569,0.874006 beta-lactamase_T261Q,beta-lactamase_261,TEM-1,beta-lactamase,P62593,0.874007,NO,261,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.88,-4.224,1.344,5.65483,0.014,E,B,0.53,-0.39,2.449,,77.62,HPP,-1.771,0.221079,0.0123091,0.874007 beta-lactamase_0_D252Q,beta-lactamase_0_252,TEM-1,beta-lactamase_0,P62593,0.874017,NO,252,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.0500837,0.00575769,0.874017 beta-lactamase_0_A132N,beta-lactamase_0_132,TEM-1,beta-lactamase_0,P62593,0.87402,NO,132,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.9,-3.872,2.972,,,H,A,0.46,-0.93,2.249,,64.69,PHH,-1.138,0.0500837,0.000962524,0.87402 beta-lactamase_0_L192Q,beta-lactamase_0_192,TEM-1,beta-lactamase_0,P62593,0.874045,NO,192,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.254,-4.246,2.992,,0.095,H,A,0.55,0.35,1.756,,60.14,HHP,-1.41833,0.0500837,0.00558728,0.874045 kka2_1:8_E59G,kka2_1:8_59,Kka2,kka2_1:8,P00552,0.87405,NO,59,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-0.952,-3.43,2.478,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.100394,0.00280355,0.87405 kka2_1:8_E59G,kka2_1:8_59,Kka2,kka2_1:8,P00552,0.87405,NO,59,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-0.952,-3.43,2.478,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.100394,0.00280355,0.87405 beta-lactamase_0_L150I,beta-lactamase_0_150,TEM-1,beta-lactamase_0,P62593,0.874082,NO,150,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.326,-3.18,1.854,,,H,A,0.55,-0.2,2.128,,62.94,HHB,-1.86167,0.0500837,0.00463171,0.874082 beta-lactamase_0_D252G,beta-lactamase_0_252,TEM-1,beta-lactamase_0,P62593,0.874097,NO,252,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.0500837,0.00575769,0.874097 beta-lactamase_0_P105V,beta-lactamase_0_105,TEM-1,beta-lactamase_0,P62593,0.874103,NO,105,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.813,-3.554,2.741,,0.226,T,A,0.52,0.8,3.48,,63.29,POH,-1.01533,0.0500837,0.0011981,0.874103 beta-lactamase_0_R273C,beta-lactamase_0_273,TEM-1,beta-lactamase_0,P62593,0.87414,NO,273,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.314,-5.09,2.776,,0.564,H,A,1.2,1.57,20.248,20.248,73.78,ABP,-1.841,0.0500837,0.0077952,0.87414 beta-lactamase_0_L248V,beta-lactamase_0_248,TEM-1,beta-lactamase_0,P62593,0.874197,NO,248,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.0500837,0.00428493,0.874197 kka2_1:1_G6L,kka2_1:1_6,Kka2,kka2_1:1,P00552,0.874214,NO,6,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.685,-3.363,1.678,,,,,,,1.292,,71.59,AOH,-1.639,0.520039,0.00204693,0.874214 beta-lactamase_R202G,beta-lactamase_202,TEM-1,beta-lactamase,P62593,0.874219,NO,202,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.292,-3.349,2.057,5.16273,0.188,H,A,0.68,0.62,1.918,,77.62,PBP,-1.54767,0.221079,0.00321899,0.874219 kka2_1:1_E149H,kka2_1:1_149,Kka2,kka2_1:1,P00552,0.874219,NO,149,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.994,-3.508,1.514,,0.674,H,A,1.04,1.63,3.671,,71.59,HAH,-1.59667,0.520039,0.00803343,0.874219 beta-lactamase_2500_G85L,beta-lactamase_2500_85,TEM-1,beta-lactamase_2500,P62593,0.874252,NO,85,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.011,-3.755,2.744,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.361275,0.00252173,0.874252 Pab1_K166H,Pab1_166,Pab1,Pab1,P04147,0.874274,NO,166,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.262,-4.269,3.007,,0.299,,l,,0,,,,PBO,-1.21033,0.175299,0.0011038,0.874274 beta-lactamase_2500_S256W,beta-lactamase_2500_256,TEM-1,beta-lactamase_2500,P62593,0.874298,NO,256,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.361275,0.00710634,0.874298 beta-lactamase_0_F228I,beta-lactamase_0_228,TEM-1,beta-lactamase_0,P62593,0.874318,NO,228,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-2.342,-3.049,0.707,,0.154,E,B,0.58,-0.42,15.504,15.504,63.29,HHH,-1.53033,0.0500837,0.0046669,0.874318 gb1_N263T,gb1_263,gb1,gb1,P06654,0.874347,NO,263,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-1.162,-2.973,1.811,,,,,,,,,,APO,-2.04233,0.177985,0.0035297,0.874347 beta-lactamase_2500_A215G,beta-lactamase_2500_215,TEM-1,beta-lactamase_2500,P62593,0.874353,NO,215,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.503,-1.579,0.076,,,,a,0.46,-0.93,3.516,,74.48,HHO,-1.42633,0.361275,0.00544007,0.874353 beta-lactamase_F149K,beta-lactamase_149,TEM-1,beta-lactamase,P62593,0.874356,NO,149,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.299,-3.859,2.56,5.54789,0.195,H,A,1.1,0.11,1.863,,63.99,HHH,-1.46067,0.221079,0.00418462,0.874356 beta-lactamase_0_L28N,beta-lactamase_0_28,TEM-1,beta-lactamase_0,P62593,0.874361,NO,28,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.579,-4.056,2.477,,0.277,H,A,0.55,-0.16,9.35,9.35,93.01,PHH,-2.11333,0.0500837,0.00359321,0.874361 beta-lactamase_0_S57W,beta-lactamase_0_57,TEM-1,beta-lactamase_0,P62593,0.874427,NO,57,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.918,-5.449,3.531,,0.352,E,B,0.27,-0.18,1.454,,72.73,APH,-2.29167,0.0500837,0.00492804,0.874427 beta-lactamase_T198V,beta-lactamase_198,TEM-1,beta-lactamase,P62593,0.874438,NO,198,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.168,-2.827,0.659,4.9209,0.489,,B,0.69,-0.13,0.37,,73.78,HPH,-1.98767,0.221079,0.004311,0.874438 kka2_1:1_H124P,kka2_1:1_124,Kka2,kka2_1:1,P00552,0.874459,NO,124,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-0.84,-3.908,3.068,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.520039,0.00211296,0.874459 beta-lactamase_T147A,beta-lactamase_147,TEM-1,beta-lactamase,P62593,0.874488,NO,147,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.149,-2.982,1.833,5.37474,0.281,H,A,0.8,-0.68,2.838,,64.34,HPH,-1.456,0.221079,0.00226017,0.874488 beta-lactamase_0_L146K,beta-lactamase_0_146,TEM-1,beta-lactamase_0,P62593,0.874542,NO,146,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.462,-3.867,2.405,,0.007,H,A,0.55,-0.56,2.051,,64.69,AHP,-1.656,0.0500837,0.00474542,0.874542 beta-lactamase_0_N134D,beta-lactamase_0_134,TEM-1,beta-lactamase_0,P62593,0.874562,NO,134,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-0.879,-3.087,2.208,,0.138,H,A,0.61,-0.6,3.776,,53.15,HPH,-1.02233,0.0500837,0.000644786,0.874562 beta-lactamase_0_E166M,beta-lactamase_0_166,TEM-1,beta-lactamase_0,P62593,0.874572,NO,166,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.756,-4.707,2.951,,0.508,G,A,1.04,1.05,17.227,17.227,73.08,OAH,-1.42233,0.0500837,0.00512989,0.874572 beta-lactamase_0_N98T,beta-lactamase_0_98,TEM-1,beta-lactamase_0,P62593,0.874601,NO,98,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-2.973,-2.907,-0.066,,0.963,G,A,0.61,1.35,14.853,14.853,77.62,PPA,-2.07867,0.0500837,0.00505389,0.874601 beta-lactamase_39_L219F,beta-lactamase_39_219,TEM-1,beta-lactamase_39,P62593,0.874605,NO,219,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.313,-2.825,1.512,,,I,A,0.55,-0.51,19.842,19.842,74.48,HHB,-1.21533,0.0495842,0.00664345,0.874605 beta-lactamase_2500_E108W,beta-lactamase_2500_108,TEM-1,beta-lactamase_2500,P62593,0.874643,NO,108,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.46,-5.465,4.005,,0.572,G,A,1.04,1.87,1.147,,72.73,PAB,-1.437,0.361275,0.00413372,0.874643 beta-lactamase_G76T,beta-lactamase_76,TEM-1,beta-lactamase,P62593,0.874666,NO,76,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.189,-2.655,1.466,4.73862,,H,A,2.05,-0.67,3.059,,67.83,OOH,-1.22267,0.221079,0.00476637,0.874666 gb1_G264H,gb1_264,gb1,gb1,P06654,0.874698,NO,264,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.833,-4.465,2.632,,,,,,,0.864,,44.87,POH,-1.61267,0.177985,0.0049716,0.874698 beta-lactamase_0_A124H,beta-lactamase_0_124,TEM-1,beta-lactamase_0,P62593,0.874737,NO,124,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.181,-4.785,3.604,,,H,A,0.46,-0.9,1.876,,64.34,HHH,-1.152,0.0500837,0.00481399,0.874737 beta-lactamase_0_L136E,beta-lactamase_0_136,TEM-1,beta-lactamase_0,P62593,0.87474,NO,136,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.232,-3.938,2.706,,,H,A,0.55,-0.34,0.648,,48.95,HHH,-1.088,0.0500837,0.00442304,0.87474 beta-lactamase_2500_E210S,beta-lactamase_2500_210,TEM-1,beta-lactamase_2500,P62593,0.874747,NO,210,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.319,-2.669,0.35,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.361275,0.00663582,0.874747 beta-lactamase_0_G265V,beta-lactamase_0_265,TEM-1,beta-lactamase_0,P62593,0.874779,NO,265,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.0500837,0.00811926,0.874779 beta-lactamase_M115I,beta-lactamase_115,TEM-1,beta-lactamase,P62593,0.874795,NO,115,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.389,-3.258,1.869,4.89743,0.019,E,B,1.3,0.08,1.236,,69.58,OHP,-1.25433,0.221079,0.0034337,0.874795 beta-lactamase_0_W163N,beta-lactamase_0_163,TEM-1,beta-lactamase_0,P62593,0.874819,NO,163,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-1.843,-2.852,1.009,,0.467,,B,0.47,-0.5,13.843,13.843,63.99,BHA,-1.269,0.0500837,0.00418955,0.874819 beta-lactamase_A124M,beta-lactamase_124,TEM-1,beta-lactamase,P62593,0.874821,NO,124,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.181,-4.519,3.338,4.58507,,H,A,0.58,-0.9,2.273,,64.34,HHH,-1.152,0.221079,0.00481399,0.874821 beta-lactamase_2500_A282C,beta-lactamase_2500_282,TEM-1,beta-lactamase_2500,P62593,0.874825,NO,282,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.361275,0.0449821,0.874825 beta-lactamase_0_Y103A,beta-lactamase_0_103,TEM-1,beta-lactamase_0,P62593,0.87483,NO,103,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-1.33,-3.426,2.096,,0.613,S,l,0.21,1.21,1.646,,63.29,AHP,-1.48767,0.0500837,0.00443048,0.87483 beta-lactamase_A9L,beta-lactamase_9,TEM-1,beta-lactamase,P62593,0.874858,NO,9,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.147,-2.334,0.187,,,,,,,5.128,,72.73,HHH,-2.04267,0.221079,0.00247263,0.874858 beta-lactamase_0_G43D,beta-lactamase_0_43,TEM-1,beta-lactamase_0,P62593,0.874879,NO,43,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.62,-3.469,2.849,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.0500837,0.00120151,0.874879 beta-lactamase_0_I244K,beta-lactamase_0_244,TEM-1,beta-lactamase_0,P62593,0.874901,NO,244,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.555,-3.812,2.257,,,E,B,0.48,-0.84,1.241,,77.62,OHH,-1.385,0.0500837,0.00605379,0.874901 Pab1_Y197T,Pab1_197,Pab1,Pab1,P04147,0.874914,NO,197,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-1.345,-3.559,2.214,,,,,,,0.891,,80.42,HHH,-1.41767,0.175299,0.00302474,0.874914 gb1_T242E,gb1_242,gb1,gb1,P06654,0.875048,NO,242,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.245,-3.175,1.93,,,,,,,,,,APP,-1.444,0.177985,0.00243886,0.875048 beta-lactamase_0_F149N,beta-lactamase_0_149,TEM-1,beta-lactamase_0,P62593,0.875049,NO,149,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.299,-4.055,2.756,,0.195,H,A,0.58,0.11,3.518,,63.99,HHH,-1.46067,0.0500837,0.00418462,0.875049 beta-lactamase_156_R220W,beta-lactamase_156_220,TEM-1,beta-lactamase_156,P62593,0.875049,NO,220,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-0.942,-5.348,4.406,,0.295,I,A,1.2,-0.76,2.164,,74.48,HBP,-1.33633,0.111618,0.00232421,0.875049 beta-lactamase_S57I,beta-lactamase_57,TEM-1,beta-lactamase,P62593,0.875054,NO,57,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.918,-3.825,1.907,5.64201,0.352,E,B,0.25,-0.18,1.971,,72.73,APH,-2.29167,0.221079,0.00492804,0.875054 beta-lactamase_2500_A170H,beta-lactamase_2500_170,TEM-1,beta-lactamase_2500,P62593,0.875078,NO,170,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.237,-4.694,3.457,,0.126,,L,0.46,-0.35,2.427,,64.69,AHH,-1.63267,0.361275,0.00431903,0.875078 beta-lactamase_156_A235R,beta-lactamase_156_235,TEM-1,beta-lactamase_156,P62593,0.875099,NO,235,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.266,-3.887,2.621,,0.32,E,B,0.46,-0.86,1.344,,50,OHO,-0.89,0.111618,0.00493474,0.875099 beta-lactamase_0_R257G,beta-lactamase_0_257,TEM-1,beta-lactamase_0,P62593,0.8751,NO,257,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.0500837,0.00756629,0.8751 Pab1_N139L,Pab1_139,Pab1,Pab1,P04147,0.875108,NO,139,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-1.079,-3.4,2.321,,0.062,H,A,,-0.73,,,,APB,-1.09667,0.175299,0.000339145,0.875108 kka2_1:2_A119C,kka2_1:2_119,Kka2,kka2_1:2,P00552,0.875179,NO,119,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.073,-4.641,3.568,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.295029,0.00441074,0.875179 kka2_1:1_L7Q,kka2_1:1_7,Kka2,kka2_1:1,P00552,0.875191,NO,7,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.926,-3.782,1.856,,,,,,,18.934,18.934,71.59,OHB,-2.12333,0.520039,0.00269456,0.875191 kka2_1:2_E63D,kka2_1:2_63,Kka2,kka2_1:2,P00552,0.875227,NO,63,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-0.762,-2.822,2.06,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.295029,0.00118399,0.875227 WW_domain_T182A,WW_domain_182,Yap65,WW_domain,P46937,0.875235,NO,182,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.149,-2.63,1.481,6.20597,,,,,,,,,BPP,-1.483,0.153962,0.00294574,0.875235 kka2_1:4_P179G,kka2_1:4_179,Kka2,kka2_1:4,P00552,0.875295,NO,179,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.974,-3.438,2.464,,0.113,,B,0.52,0.69,10.913,10.913,56.06,HOA,-2.19867,0.168804,0.00298346,0.875295 beta-lactamase_D161S,beta-lactamase_161,TEM-1,beta-lactamase,P62593,0.875323,NO,161,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.891,-2.488,1.597,5.12208,0.341,,A,0.23,-0.52,1.602,,61.19,HAB,-0.961333,0.221079,0.000897697,0.875323 beta-lactamase_L192T,beta-lactamase_192,TEM-1,beta-lactamase,P62593,0.875323,NO,192,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.254,-3.48,2.226,5.68899,0.095,H,A,1.3,0.35,1.756,,60.14,HHP,-1.41833,0.221079,0.00558728,0.875323 beta-lactamase_0_T178V,beta-lactamase_0_178,TEM-1,beta-lactamase_0,P62593,0.875339,NO,178,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-0.791,-3.079,2.288,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.0500837,0.000684366,0.875339 gb1_G264M,gb1_264,gb1,gb1,P06654,0.875397,NO,264,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.833,-4.317,2.484,,,,,,,0.864,,44.87,POH,-1.61267,0.177985,0.0049716,0.875397 beta-lactamase_2500_A182D,beta-lactamase_2500_182,TEM-1,beta-lactamase_2500,P62593,0.875402,NO,182,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.777,-2.705,0.928,,0.136,H,A,0.46,-0.66,2.032,,93.01,OHH,-1.27367,0.361275,0.00559099,0.875402 beta-lactamase_0_R202Y,beta-lactamase_0_202,TEM-1,beta-lactamase_0,P62593,0.875434,NO,202,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.292,-4.182,2.89,,0.188,H,A,1.2,0.62,7.016,,77.62,PBP,-1.54767,0.0500837,0.00321899,0.875434 beta-lactamase_625_G240N,beta-lactamase_625_240,TEM-1,beta-lactamase_625,P62593,0.87545,NO,240,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.213352,0.00591201,0.87545 beta-lactamase_0_D231Y,beta-lactamase_0_231,TEM-1,beta-lactamase_0,P62593,0.875479,NO,231,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.816,-4.385,3.569,,,E,B,0.75,-1.06,4.975,,65.38,HAB,-0.994,0.0500837,0.00107395,0.875479 Pab1_N132D,Pab1_132,Pab1,Pab1,P04147,0.875624,NO,132,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-1.079,-2.836,1.757,,0.412,S,l,,0.9,,,,BPH,-1.067,0.175299,0.000347671,0.875624 kka2_1:8_T28F,kka2_1:8_28,Kka2,kka2_1:8,P00552,0.875641,NO,28,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.883,-4.355,2.472,,0.353,S,B,0.22,2.02,18.114,18.114,63.64,PPH,-1.74467,0.100394,0.00743084,0.875641 kka2_1:8_T28F,kka2_1:8_28,Kka2,kka2_1:8,P00552,0.875641,NO,28,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.883,-4.355,2.472,,0.353,S,B,0.22,2.02,18.114,18.114,63.64,PPH,-1.74467,0.100394,0.00743084,0.875641 kka2_1:4_A41V,kka2_1:4_41,Kka2,kka2_1:4,P00552,0.875649,NO,41,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.879,-2.914,1.035,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.168804,0.00543332,0.875649 beta-lactamase_0_L167D,beta-lactamase_0_167,TEM-1,beta-lactamase_0,P62593,0.875698,NO,167,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.138,-4.03,2.892,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.0500837,0.00303566,0.875698 kka2_1:1_T146Q,kka2_1:1_146,Kka2,kka2_1:1,P00552,0.875726,NO,146,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.978,-2.971,-0.007,,0.281,H,A,0.82,0.78,2.105,,92.05,BPB,-1.96833,0.520039,0.00606474,0.875726 beta-lactamase_0_H156Q,beta-lactamase_0_156,TEM-1,beta-lactamase_0,P62593,0.875786,NO,156,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-3.156,-2.776,-0.38,,0.753,S,A,0.17,-0.6,23.367,23.367,77.62,ABH,-1.932,0.0500837,0.00468596,0.875786 beta-lactamase_M268N,beta-lactamase_268,TEM-1,beta-lactamase,P62593,0.87585,NO,268,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-2.023,-4.092,2.069,5.4797,0.471,H,A,0.09,0.3,1.071,,65.73,PHA,-2.16233,0.221079,0.0102525,0.87585 beta-lactamase_0_G194H,beta-lactamase_0_194,TEM-1,beta-lactamase_0,P62593,0.875861,NO,194,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.396,-4.628,3.232,,0.276,S,b,0.29,0.36,3.017,,67.83,POA,-1.832,0.0500837,0.00392163,0.875861 beta-lactamase_I11T,beta-lactamase_11,TEM-1,beta-lactamase,P62593,0.875918,NO,11,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.745,-3.383,1.638,,,,,,,3.135,,66.08,HHO,-1.79467,0.221079,0.00261325,0.875918 kka2_1:8_A34Q,kka2_1:8_34,Kka2,kka2_1:8,P00552,0.875921,NO,34,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.928,-3.9,2.972,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.100394,0.00343484,0.875921 kka2_1:8_A34Q,kka2_1:8_34,Kka2,kka2_1:8,P00552,0.875921,NO,34,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.928,-3.9,2.972,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.100394,0.00343484,0.875921 Pab1_K140N,Pab1_140,Pab1,Pab1,P04147,0.875965,NO,140,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.083,-3.265,2.182,,0.345,H,A,,-0.73,,,,PBH,-1.20767,0.175299,0.000337366,0.875965 beta-lactamase_0_L136V,beta-lactamase_0_136,TEM-1,beta-lactamase_0,P62593,0.876049,NO,136,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.232,-1.932,0.7,,,H,A,0.55,-0.34,0.648,,48.95,HHH,-1.088,0.0500837,0.00442304,0.876049 kka2_1:8_I228T,kka2_1:8_228,Kka2,kka2_1:8,P00552,0.876078,NO,228,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.142,-3.482,2.34,,,H,A,1.52,-1.2,1.521,,71.59,AHH,-1.54633,0.100394,0.00458834,0.876078 kka2_1:8_I228T,kka2_1:8_228,Kka2,kka2_1:8,P00552,0.876078,NO,228,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.142,-3.482,2.34,,,H,A,1.52,-1.2,1.521,,71.59,AHH,-1.54633,0.100394,0.00458834,0.876078 beta-lactamase_0_A40L,beta-lactamase_0_40,TEM-1,beta-lactamase_0,P62593,0.876101,NO,40,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.402,-3.399,1.997,,0.155,S,B,0.46,0.21,0.783,,73.78,OHB,-1.40267,0.0500837,0.00490026,0.876101 beta-lactamase_2500_H110L,beta-lactamase_2500_110,TEM-1,beta-lactamase_2500,P62593,0.876119,NO,110,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-1.706,-3.515,1.809,,0.341,G,a,0.17,1.08,31.31,31.31,64.69,BBH,-1.73333,0.361275,0.00441499,0.876119 PSD95pdz3_F325T,PSD95pdz3_325,PSD95pdz3,PSD95pdz3,P31016,0.876146,NO,325,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.524,-3.328,1.804,5.50654,,,,,12.7236,,,,OHP,-1.314,0.0758425,0.00102273,0.876146 beta-lactamase_0_P25C,beta-lactamase_0_25,TEM-1,beta-lactamase_0,P62593,0.876173,NO,25,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.526,-5.046,3.52,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.0500837,0.00347571,0.876173 beta-lactamase_0_L100N,beta-lactamase_0_100,TEM-1,beta-lactamase_0,P62593,0.876206,NO,100,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.218,-4.207,2.989,,0.343,,B,0.55,0.13,1.373,,63.29,AHH,-1.23467,0.0500837,0.00413885,0.876206 beta-lactamase_2500_H24C,beta-lactamase_2500_24,TEM-1,beta-lactamase_2500,P62593,0.876214,NO,24,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-2.481,-4.897,2.416,,,,,,,0.467,,93.01,OBO,-2.0035,0.361275,0.00238894,0.876214 hsp90_G584A,hsp90_584,hsp90,hsp90,P02829,0.876216,NO,584,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-2.511,-2.456,0,5.20094,0.414,S,b,0.84,0.33,,,,HOH,-3.32733,0.368192,0.000222939,0.876216 beta-lactamase_I140M,beta-lactamase_140,TEM-1,beta-lactamase,P62593,0.876218,NO,140,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.733,-4.137,2.404,5.29918,0.128,H,A,1,0.41,1.16,,73.08,PHO,-1.48733,0.221079,0.00597777,0.876218 beta-lactamase_K109P,beta-lactamase_109,TEM-1,beta-lactamase,P62593,0.876218,NO,109,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.734,-2.825,1.091,6.05842,0.787,G,A,1.82,2.21,21.623,21.623,72.73,ABB,-1.63333,0.221079,0.00462493,0.876218 beta-lactamase_P249D,beta-lactamase_249,TEM-1,beta-lactamase,P62593,0.876218,NO,249,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.312,-2.815,1.503,5.10655,0.256,S,B,0.99,0.04,0.479,,72.73,OOA,-1.81367,0.221079,0.00220169,0.876218 beta-lactamase_2500_R63L,beta-lactamase_2500_63,TEM-1,beta-lactamase_2500,P62593,0.876221,NO,63,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-0.943,-2.476,1.533,,0.218,,B,1.2,-0.31,0.929,,44.06,ABH,-0.992333,0.361275,0.00126938,0.876221 beta-lactamase_0_V259Q,beta-lactamase_0_259,TEM-1,beta-lactamase_0,P62593,0.876264,NO,259,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.0500837,0.0070773,0.876264 beta-lactamase_0_P224E,beta-lactamase_0_224,TEM-1,beta-lactamase_0,P62593,0.876308,NO,224,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.893,-3.439,2.546,,0.383,,B,0.52,-0.3,3.587,,74.48,HOH,-1.26433,0.0500837,0.00189564,0.876308 beta-lactamase_0_S51F,beta-lactamase_0_51,TEM-1,beta-lactamase_0,P62593,0.876316,NO,51,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.526,-4.284,2.758,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.0500837,0.00504821,0.876316 beta-lactamase_V101N,beta-lactamase_101,TEM-1,beta-lactamase,P62593,0.87645,NO,101,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.295,-4.085,2.79,5.49045,0.342,,B,0.96,0,1.675,,73.08,HHA,-1.54367,0.221079,0.00374492,0.87645 kka2_1:1_V75A,kka2_1:1_75,Kka2,kka2_1:1,P00552,0.876469,NO,75,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-2.06,-3.254,1.194,,0.042,.,B,0.44,-0.2,2.815,,71.59,OHO,-1.563,0.520039,0.00693733,0.876469 beta-lactamase_0_G90H,beta-lactamase_0_90,TEM-1,beta-lactamase_0,P62593,0.876494,NO,90,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-2.091,-3.353,1.262,,0.598,T,A,0.29,0.32,2.04,,77.62,HOB,-1.52633,0.0500837,0.00490273,0.876494 beta-lactamase_0_E195R,beta-lactamase_0_195,TEM-1,beta-lactamase_0,P62593,0.876498,NO,195,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.186,-3.074,0.888,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.0500837,0.00496565,0.876498 beta-lactamase_0_P217A,beta-lactamase_0_217,TEM-1,beta-lactamase_0,P62593,0.876549,NO,217,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-2.062,-1.891,-0.171,,0.496,I,A,0.52,-0.33,1.087,,74.48,OOH,-1.64333,0.0500837,0.00463211,0.876549 WW_domain_T196N,WW_domain_196,Yap65,WW_domain,P46937,0.876575,NO,196,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.782,-2.496,0.714,5.5744,,,,,,5.836,,70.04,PPP,-1.732,0.153962,0.00421377,0.876575 beta-lactamase_S264N,beta-lactamase_264,TEM-1,beta-lactamase,P62593,0.876576,NO,264,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.985,-2.537,0.552,4.67475,0.04,,B,0.25,0.29,34.251,34.251,73.78,OPP,-2.19867,0.221079,0.0119399,0.876576 beta-lactamase_T126D,beta-lactamase_126,TEM-1,beta-lactamase,P62593,0.876576,NO,126,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.122,-2.344,1.222,4.82694,0.05,H,A,0.3,-0.05,1.14,,44.41,HPH,-1.60467,0.221079,0.00244552,0.876576 kka2_1:8_R122G,kka2_1:8_122,Kka2,kka2_1:8,P00552,0.876581,NO,122,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.175,-2.63,0.455,,0.487,H,A,1.2,0.26,22.675,22.675,71.59,BBH,-1.53833,0.100394,0.00736512,0.876581 kka2_1:8_R122G,kka2_1:8_122,Kka2,kka2_1:8,P00552,0.876581,NO,122,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.175,-2.63,0.455,,0.487,H,A,1.2,0.26,22.675,22.675,71.59,BBH,-1.53833,0.100394,0.00736512,0.876581 beta-lactamase_0_L120M,beta-lactamase_0_120,TEM-1,beta-lactamase_0,P62593,0.876598,NO,120,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.044,-4.046,3.002,,,H,A,0.55,-1.13,1.2,,64.69,AHO,-1.13633,0.0500837,0.00143563,0.876598 kka2_1:4_R258Q,kka2_1:4_258,Kka2,kka2_1:4,P00552,0.876631,NO,258,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.626,-2.106,0.48,,0.316,H,A,1.2,-0.85,2.655,,53.03,HBH,-1.25933,0.168804,0.00983174,0.876631 beta-lactamase_0_R63Y,beta-lactamase_0_63,TEM-1,beta-lactamase_0,P62593,0.876642,NO,63,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-0.943,-4.16,3.217,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.0500837,0.00126938,0.876642 beta-lactamase_E195Y,beta-lactamase_195,TEM-1,beta-lactamase,P62593,0.876708,NO,195,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.186,-4.374,2.188,7.28489,1.016,S,A,1.52,0.85,2.583,,77.62,OAH,-2.02,0.221079,0.00496565,0.876708 beta-lactamase_L111E,beta-lactamase_111,TEM-1,beta-lactamase,P62593,0.876708,NO,111,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.76,-3.773,2.013,5.8705,0.328,T,A,0.84,0.93,3.836,,64.34,BHP,-1.884,0.221079,0.00480671,0.876708 beta-lactamase_T262D,beta-lactamase_262,TEM-1,beta-lactamase,P62593,0.876708,NO,262,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.332,-3.588,2.256,5.06002,0.108,E,B,0.3,-0.55,1.423,,67.83,PPO,-2.081,0.221079,0.00853516,0.876708 kka2_1:2_I2G,kka2_1:2_2,Kka2,kka2_1:2,P00552,0.876734,NO,2,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.787,-3.438,1.651,,,,,,,5.773,,71.59,HHA,-1.92433,0.295029,0.00246644,0.876734 Pab1_N162P,Pab1_162,Pab1,Pab1,P04147,0.876784,NO,162,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-2.313,-3.952,1.639,,0.681,T,A,,1.12,,,,APO,-1.532,0.175299,0.0030719,0.876784 beta-lactamase_2500_R239P,beta-lactamase_2500_239,TEM-1,beta-lactamase_2500,P62593,0.876856,NO,239,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.361275,0.00213852,0.876856 beta-lactamase_0_W288S,beta-lactamase_0_288,TEM-1,beta-lactamase_0,P62593,0.876896,NO,288,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,,,,,,,,,,,,,BHO,,0.0500837,,0.876896 PSD95pdz3_N363I,PSD95pdz3_363,PSD95pdz3,PSD95pdz3,P31016,0.876906,NO,363,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-1.41,-3.692,2.282,5.23349,,,,,20.7037,,,,HPO,-1.29433,0.0758425,0.000524014,0.876906 beta-lactamase_0_S266P,beta-lactamase_0_266,TEM-1,beta-lactamase_0,P62593,0.876928,NO,266,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.0500837,0.0140785,0.876928 beta-lactamase_R92C,beta-lactamase_92,TEM-1,beta-lactamase,P62593,0.876953,NO,92,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.718,-5.119,3.401,5.65832,0.479,E,B,0.91,1.36,3.069,,65.38,BBH,-1.50367,0.221079,0.00429626,0.876953 PSD95pdz3_A375T,PSD95pdz3_375,PSD95pdz3,PSD95pdz3,P31016,0.876981,NO,375,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.307,-2.878,1.571,5.05512,,,,,13.888,,,,PHH,-1.43767,0.0758425,0.000356809,0.876981 beta-lactamase_0_K32F,beta-lactamase_0_32,TEM-1,beta-lactamase_0,P62593,0.877019,NO,32,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.984,-4.328,2.344,,0.563,H,A,2.34,0.34,0.418,,73.08,HBA,-2.04233,0.0500837,0.00401283,0.877019 kka2_1:2_V46Q,kka2_1:2_46,Kka2,kka2_1:2,P00552,0.877098,NO,46,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-2.62,-4.138,1.518,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.295029,0.00631301,0.877098 E1_Ubiquitin_G47I,E1_Ubiquitin_47,Uba1,E1_Ubiquitin,P0CG63,0.8771,NO,47,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.999,-4.046,3.047,,0.057,T,l,,-1.21,,,,HOB,-1.195,0.18783,0.00142261,0.8771 beta-lactamase_R7L,beta-lactamase_7,TEM-1,beta-lactamase,P62593,0.877109,NO,7,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.683,-2.112,0.429,,,,,,,2.44,,67.13,HBH,-1.96267,0.221079,0.00211375,0.877109 beta-lactamase_L188A,beta-lactamase_188,TEM-1,beta-lactamase,P62593,0.877111,NO,188,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.166,-2.542,1.376,5.55434,,H,A,1.07,-0.3,1.574,,60.14,PHB,-1.47033,0.221079,0.00295687,0.877111 beta-lactamase_A183G,beta-lactamase_183,TEM-1,beta-lactamase,P62593,0.877123,NO,183,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.231,-3.077,1.846,4.84712,0.155,H,A,0.55,-0.91,12.189,,77.62,HHH,-1.53367,0.221079,0.00296631,0.877123 kka2_1:8_T51I,kka2_1:8_51,Kka2,kka2_1:8,P00552,0.877131,NO,51,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.199,-2.59,0.391,,0.05,E,B,0.82,-0.05,5.399,,63.64,BPA,-1.76767,0.100394,0.00628861,0.877131 kka2_1:8_T51I,kka2_1:8_51,Kka2,kka2_1:8,P00552,0.877131,NO,51,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.199,-2.59,0.391,,0.05,E,B,0.82,-0.05,5.399,,63.64,BPA,-1.76767,0.100394,0.00628861,0.877131 gb1_T242G,gb1_242,gb1,gb1,P06654,0.877133,NO,242,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.245,-3.094,1.849,,,,,,,,,,APP,-1.444,0.177985,0.00243886,0.877133 Pab1_I157A,Pab1_157,Pab1,Pab1,P04147,0.877158,NO,157,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.623,-2.835,1.212,,,,,,,1.439,,79.72,BHH,-1.28667,0.175299,0.0018103,0.877158 kka2_1:1_E63L,kka2_1:1_63,Kka2,kka2_1:1,P00552,0.877227,NO,63,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-0.762,-3.611,2.849,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.520039,0.00118399,0.877227 beta-lactamase_0_L223S,beta-lactamase_0_223,TEM-1,beta-lactamase_0,P62593,0.877271,NO,223,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.055,-3.587,2.532,,0.27,,B,0.55,0.09,1.633,,74.48,HHO,-1.35033,0.0500837,0.00372793,0.877271 beta-lactamase_156_G142M,beta-lactamase_156_142,TEM-1,beta-lactamase_156,P62593,0.877296,NO,142,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.707,-4.893,4.186,,0.034,,p,0.29,-0.64,0.325,,64.69,OOO,-0.834,0.111618,0.00060149,0.877296 beta-lactamase_F149H,beta-lactamase_149,TEM-1,beta-lactamase,P62593,0.877313,NO,149,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.299,-4.304,3.005,5.54789,0.195,H,A,1.1,0.11,1.863,,63.99,HHH,-1.46067,0.221079,0.00418462,0.877313 beta-lactamase_V257C,beta-lactamase_257,TEM-1,beta-lactamase,P62593,0.877313,NO,257,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.533,-4.718,3.185,5.31999,,E,B,0.96,-0.7,1.463,,58.74,HHH,-1.70967,0.221079,0.00756629,0.877313 kka2_1:2_D134G,kka2_1:2_134,Kka2,kka2_1:2,P00552,0.877341,NO,134,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.969,-3.259,2.29,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.295029,0.00270812,0.877341 beta-lactamase_F228T,beta-lactamase_228,TEM-1,beta-lactamase,P62593,0.877344,NO,228,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-2.342,-2.522,0.18,5.33448,0.154,E,B,1.1,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.221079,0.0046669,0.877344 beta-lactamase_0_E26R,beta-lactamase_0_26,TEM-1,beta-lactamase_0,P62593,0.877345,NO,26,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.454,-2.433,-0.021,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.0500837,0.00297948,0.877345 beta-lactamase_G242S,beta-lactamase_242,TEM-1,beta-lactamase,P62593,0.877376,NO,242,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.319,-2.324,1.005,4.68003,,E,B,0.87,-1.05,1.079,,50,BOH,-1.428,0.221079,0.00452879,0.877376 kka2_1:8_L107F,kka2_1:8_107,Kka2,kka2_1:8,P00552,0.877417,NO,107,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.238,-3.877,2.639,,0.197,.,B,0.55,-1.1,4.478,,71.59,BHH,-2.143,0.100394,0.00561937,0.877417 kka2_1:8_L107F,kka2_1:8_107,Kka2,kka2_1:8,P00552,0.877417,NO,107,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.238,-3.877,2.639,,0.197,.,B,0.55,-1.1,4.478,,71.59,BHH,-2.143,0.100394,0.00561937,0.877417 beta-lactamase_A170D,beta-lactamase_170,TEM-1,beta-lactamase,P62593,0.877446,NO,170,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.237,-3.712,2.475,5.19261,0.126,,L,2.34,-0.35,2.427,,64.69,AHH,-1.63267,0.221079,0.00431903,0.877446 beta-lactamase_625_V72L,beta-lactamase_625_72,TEM-1,beta-lactamase_625,P62593,0.877456,NO,72,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.658,-2.403,0.745,,,H,A,0.44,-1.03,0.981,,65.73,BHH,-1.32167,0.213352,0.00501194,0.877456 beta-lactamase_0_Q276C,beta-lactamase_0_276,TEM-1,beta-lactamase_0,P62593,0.87746,NO,276,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.0500837,0.0191712,0.87746 beta-lactamase_0_P172T,beta-lactamase_0_172,TEM-1,beta-lactamase_0,P62593,0.877519,NO,172,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.998,-3.409,2.411,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.0500837,0.00312594,0.877519 beta-lactamase_0_P105H,beta-lactamase_0_105,TEM-1,beta-lactamase_0,P62593,0.877545,NO,105,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.813,-4.678,3.865,,0.226,T,A,0.52,0.8,3.48,,63.29,POH,-1.01533,0.0500837,0.0011981,0.877545 beta-lactamase_I259C,beta-lactamase_259,TEM-1,beta-lactamase,P62593,0.877578,NO,259,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.522,-4.761,3.239,5.28457,,E,B,1,-0.8,1.24,,64.34,HHH,-1.53267,0.221079,0.0070773,0.877578 kka2_1:4_P132R,kka2_1:4_132,Kka2,kka2_1:4,P00552,0.877647,NO,132,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.775,-3.959,3.184,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.168804,0.0018489,0.877647 kka2_1:8_V36M,kka2_1:8_36,Kka2,kka2_1:8,P00552,0.877703,NO,36,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-0.898,-4.103,3.205,,0.292,E,B,1.48,0.21,0.938,,52.27,HHH,-1.484,0.100394,0.00245633,0.877703 kka2_1:8_V36M,kka2_1:8_36,Kka2,kka2_1:8,P00552,0.877703,NO,36,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-0.898,-4.103,3.205,,0.292,E,B,1.48,0.21,0.938,,52.27,HHH,-1.484,0.100394,0.00245633,0.877703 WW_domain_M179I,WW_domain_179,Yap65,WW_domain,P46937,0.877729,NO,179,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.541,-2.887,1.346,6.54704,,,,,,,,,AHH,-1.31367,0.153962,0.00400164,0.877729 kka2_1:8_L212A,kka2_1:8_212,Kka2,kka2_1:8,P00552,0.877751,NO,212,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.904,-2.253,1.349,,,,B,1.59,-0.78,1.708,,42.42,BHO,-0.799667,0.100394,0.0031426,0.877751 kka2_1:8_L212A,kka2_1:8_212,Kka2,kka2_1:8,P00552,0.877751,NO,212,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.904,-2.253,1.349,,,,B,1.59,-0.78,1.708,,42.42,BHO,-0.799667,0.100394,0.0031426,0.877751 beta-lactamase_D48Q,beta-lactamase_48,TEM-1,beta-lactamase,P62593,0.877802,NO,48,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.101,-3.681,2.58,4.89966,0.189,E,B,0.23,0.21,1.281,,50.35,HAH,-1.62467,0.221079,0.0027273,0.877802 beta-lactamase_0_T186G,beta-lactamase_0_186,TEM-1,beta-lactamase_0,P62593,0.877818,NO,186,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.522,-2.403,-0.119,,0.396,H,A,0.22,-0.28,16.606,16.606,77.62,HPP,-1.77633,0.0500837,0.00485034,0.877818 beta-lactamase_0_I45D,beta-lactamase_0_45,TEM-1,beta-lactamase_0,P62593,0.877823,NO,45,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-2.421,-3.902,1.481,,,E,B,0.48,-0.3,1.375,,77.62,HHA,-2.30267,0.0500837,0.00452842,0.877823 beta-lactamase_0_A230H,beta-lactamase_0_230,TEM-1,beta-lactamase_0,P62593,0.877838,NO,230,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.154,-4.737,3.583,,0.01,E,B,0.46,-1.17,2.179,,50,HHA,-1.079,0.0500837,0.00516841,0.877838 kka2_1:8_G55C,kka2_1:8_55,Kka2,kka2_1:8,P00552,0.877846,NO,55,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.625,-5.134,3.509,,0.517,S,b,0.29,1.19,8.881,,63.64,POH,-2.05967,0.100394,0.00667877,0.877846 kka2_1:8_G55C,kka2_1:8_55,Kka2,kka2_1:8,P00552,0.877846,NO,55,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.625,-5.134,3.509,,0.517,S,b,0.29,1.19,8.881,,63.64,POH,-2.05967,0.100394,0.00667877,0.877846 kka2_1:8_D82K,kka2_1:8_82,Kka2,kka2_1:8,P00552,0.877863,NO,82,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.946,-3.004,1.058,,0.341,E,b,0.29,0.52,7.463,,63.64,HAH,-1.98,0.100394,0.00637516,0.877863 kka2_1:8_D82K,kka2_1:8_82,Kka2,kka2_1:8,P00552,0.877863,NO,82,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.946,-3.004,1.058,,0.341,E,b,0.29,0.52,7.463,,63.64,HAH,-1.98,0.100394,0.00637516,0.877863 beta-lactamase_H5A,beta-lactamase_5,TEM-1,beta-lactamase,P62593,0.877869,NO,5,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-2.698,-3.197,0.499,,,,,,,1.865,,72.73,PBH,-2.36967,0.221079,0.00292712,0.877869 beta-lactamase_T267Y,beta-lactamase_267,TEM-1,beta-lactamase,P62593,0.877869,NO,267,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.308,-4.392,2.084,5.28263,0.54,,B,0.69,-0.14,0.374,,73.78,HPH,-1.9,0.221079,0.0102128,0.877869 kka2_1:8_R147S,kka2_1:8_147,Kka2,kka2_1:8,P00552,0.877894,NO,147,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.123,-3.438,2.315,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.100394,0.00549168,0.877894 kka2_1:8_R147S,kka2_1:8_147,Kka2,kka2_1:8,P00552,0.877894,NO,147,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.123,-3.438,2.315,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.100394,0.00549168,0.877894 kka2_1:2_M116I,kka2_1:2_116,Kka2,kka2_1:2,P00552,0.877905,NO,116,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-2.482,-2.646,0.164,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.295029,0.00745147,0.877905 beta-lactamase_L55N,beta-lactamase_55,TEM-1,beta-lactamase,P62593,0.87791,NO,55,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.86,-4.216,2.356,,0.372,E,A,1.07,-0.36,1.423,,63.99,HHA,-2.247,0.221079,0.00403741,0.87791 beta-lactamase_P25G,beta-lactamase_25,TEM-1,beta-lactamase,P62593,0.877938,NO,25,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.526,-2.198,0.672,5.6134,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.221079,0.00347571,0.877938 beta-lactamase_Y95L,beta-lactamase_95,TEM-1,beta-lactamase,P62593,0.877957,NO,95,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-1.715,-2.545,0.83,5.67068,0.122,,b,0.96,-0.37,2.341,,77.62,BHP,-2.16167,0.221079,0.00479449,0.877957 kka2_1:4_L102M,kka2_1:4_102,Kka2,kka2_1:4,P00552,0.877974,NO,102,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.804,-2.818,2.014,,,T,A,0.55,-1.17,0.65,,42.42,AHH,-1.398,0.168804,0.00201332,0.877974 beta-lactamase_M66C,beta-lactamase_66,TEM-1,beta-lactamase,P62593,0.877984,NO,66,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.362,-4.734,3.372,5.29561,0.013,,A,1.3,-0.7,1.319,,73.08,OHH,-1.49567,0.221079,0.00412876,0.877984 beta-lactamase_0_I229M,beta-lactamase_0_229,TEM-1,beta-lactamase_0,P62593,0.87802,NO,229,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.267,-4.125,2.858,,0.083,E,B,0.48,-0.76,1.69,,50,HHH,-1.58767,0.0500837,0.00477249,0.87802 beta-lactamase_0_L79S,beta-lactamase_0_79,TEM-1,beta-lactamase_0,P62593,0.878028,NO,79,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.842,-3.608,2.766,,0.007,H,A,0.55,-0.16,5.053,,50.35,HHP,-1.44333,0.0500837,0.000947397,0.878028 kka2_1:2_E231Q,kka2_1:2_231,Kka2,kka2_1:2,P00552,0.878043,NO,231,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.002,-3.771,1.769,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.295029,0.00732383,0.878043 kka2_1:2_L232P,kka2_1:2_232,Kka2,kka2_1:2,P00552,0.878137,NO,232,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.514,-4.306,2.792,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.295029,0.00800103,0.878137 beta-lactamase_156_V42S,beta-lactamase_156_42,TEM-1,beta-lactamase_156,P62593,0.878143,NO,42,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.564,-3.633,2.069,,0.017,E,B,0.44,-0.51,2.576,,63.99,BHO,-1.042,0.111618,0.00404515,0.878143 Pab1_V148K,Pab1_148,Pab1,Pab1,P04147,0.878159,NO,148,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.875,-3.456,1.581,,,,,,,,,,PHH,-1.43033,0.175299,0.00179641,0.878159 beta-lactamase_0_R239N,beta-lactamase_0_239,TEM-1,beta-lactamase_0,P62593,0.878194,NO,239,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.0500837,0.00213852,0.878194 PSD95pdz3_N381P,PSD95pdz3_381,PSD95pdz3,PSD95pdz3,P31016,0.878265,NO,381,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-1.41,-3.561,2.151,5.66057,,,,,28.2162,,,,BPH,-1.37767,0.0758425,0.000265374,0.878265 kka2_1:4_A215S,kka2_1:4_215,Kka2,kka2_1:4,P00552,0.878293,NO,215,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.968,-1.873,0.905,,0.039,E,B,0.46,-0.59,0.754,,50.38,HHA,-1.00467,0.168804,0.00529129,0.878293 kka2_1:8_L107V,kka2_1:8_107,Kka2,kka2_1:8,P00552,0.878323,NO,107,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.238,-2.216,0.978,,0.197,.,B,0.55,-1.1,4.478,,71.59,BHH,-2.143,0.100394,0.00561937,0.878323 kka2_1:8_L107V,kka2_1:8_107,Kka2,kka2_1:8,P00552,0.878323,NO,107,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.238,-2.216,0.978,,0.197,.,B,0.55,-1.1,4.478,,71.59,BHH,-2.143,0.100394,0.00561937,0.878323 beta-lactamase_625_S104N,beta-lactamase_625_104,TEM-1,beta-lactamase_625,P62593,0.87834,NO,104,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.015,-3.421,2.406,,0.04,,b,0.27,0.57,1.76,,63.29,HPO,-1.05267,0.213352,0.00218083,0.87834 beta-lactamase_0_F70I,beta-lactamase_0_70,TEM-1,beta-lactamase_0,P62593,0.878367,NO,70,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.169,-3.353,2.184,,,H,A,0.58,-1.34,2.153,,63.99,PHB,-0.980667,0.0500837,0.00193499,0.878367 beta-lactamase_P217Y,beta-lactamase_217,TEM-1,beta-lactamase,P62593,0.878382,NO,217,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-2.062,-4.376,2.314,5.19872,0.496,I,A,0.99,-0.33,0.431,,74.48,OOH,-1.64333,0.221079,0.00463211,0.878382 kka2_1:8_A108V,kka2_1:8_108,Kka2,kka2_1:8,P00552,0.878394,NO,108,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.061,-3.068,1.007,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.100394,0.00751209,0.878394 kka2_1:8_A108V,kka2_1:8_108,Kka2,kka2_1:8,P00552,0.878394,NO,108,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.061,-3.068,1.007,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.100394,0.00751209,0.878394 beta-lactamase_0_L167R,beta-lactamase_0_167,TEM-1,beta-lactamase_0,P62593,0.878439,NO,167,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.138,-2.876,1.738,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.0500837,0.00303566,0.878439 Pab1_D138L,Pab1_138,Pab1,Pab1,P04147,0.878471,NO,138,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.128,-3.619,2.491,,0.427,,B,,-0.03,,,,HAP,-1.13967,0.175299,0.000567877,0.878471 PSD95pdz3_R312P,PSD95pdz3_312,PSD95pdz3,PSD95pdz3,P31016,0.87852,NO,312,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.582,-3.561,1.979,5.76826,,,,,12.2409,,,,OBB,-1.46667,0.0758425,0.00196255,0.87852 beta-lactamase_L192W,beta-lactamase_192,TEM-1,beta-lactamase,P62593,0.878545,NO,192,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.254,-5.176,3.922,5.68899,0.095,H,A,1.3,0.35,1.756,,60.14,HHP,-1.41833,0.221079,0.00558728,0.878545 beta-lactamase_R91N,beta-lactamase_91,TEM-1,beta-lactamase,P62593,0.878545,NO,91,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.392,-3.596,2.204,5.92536,0.444,,B,0.68,0.96,1.318,,50.35,OBB,-1.73367,0.221079,0.00380226,0.878545 kka2_1:4_D183G,kka2_1:4_183,Kka2,kka2_1:4,P00552,0.878604,NO,183,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.204,-3.336,2.132,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.168804,0.00426304,0.878604 beta-lactamase_2500_A34T,beta-lactamase_2500_34,TEM-1,beta-lactamase_2500,P62593,0.878608,NO,34,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.059,-2.5,0.441,,,H,A,0.46,-0.54,2.921,,73.78,AHA,-1.74967,0.361275,0.00407913,0.878608 kka2_1:8_D183K,kka2_1:8_183,Kka2,kka2_1:8,P00552,0.878608,NO,183,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.204,-3.416,2.212,,0.518,.,b,0.75,0.25,0.347,,52.27,AAH,-1.40533,0.100394,0.00426304,0.878608 kka2_1:8_D183K,kka2_1:8_183,Kka2,kka2_1:8,P00552,0.878608,NO,183,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.204,-3.416,2.212,,0.518,.,b,0.75,0.25,0.347,,52.27,AAH,-1.40533,0.100394,0.00426304,0.878608 beta-lactamase_I259M,beta-lactamase_259,TEM-1,beta-lactamase,P62593,0.87875,NO,259,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.522,-3.118,1.596,5.28457,,E,B,1,-0.8,1.24,,64.34,HHH,-1.53267,0.221079,0.0070773,0.87875 beta-lactamase_0_L167H,beta-lactamase_0_167,TEM-1,beta-lactamase_0,P62593,0.878782,NO,167,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.138,-4.852,3.714,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.0500837,0.00303566,0.878782 kka2_1:2_A64M,kka2_1:2_64,Kka2,kka2_1:2,P00552,0.8788,NO,64,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.496,-4.439,2.943,,0.039,H,A,0.46,-0.57,14.509,14.509,56.06,AHH,-1.334,0.295029,0.00705578,0.8788 beta-lactamase_F17S,beta-lactamase_17,TEM-1,beta-lactamase,P62593,0.878803,NO,17,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-2.337,-2.457,0.12,,,,,,,2.192,,67.83,HHO,-2.17733,0.221079,0.00216499,0.878803 beta-lactamase_I3D,beta-lactamase_3,TEM-1,beta-lactamase,P62593,0.878803,NO,3,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-2.143,-3.811,1.668,,,,,,,3.946,,93.01,PHP,-2.21633,0.221079,0.00349304,0.878803 kka2_1:2_L81W,kka2_1:2_81,Kka2,kka2_1:2,P00552,0.878825,NO,81,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.427,-5.367,3.94,,0.46,E,A,1.59,-0.14,1.895,,63.64,HHA,-1.50567,0.295029,0.00805839,0.878825 gb1_G264T,gb1_264,gb1,gb1,P06654,0.87885,NO,264,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.833,-3.314,1.481,,,,,,,0.864,,44.87,POH,-1.61267,0.177985,0.0049716,0.87885 kka2_1:4_W69G,kka2_1:4_69,Kka2,kka2_1:4,P00552,0.878864,NO,69,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-0.859,-3.43,2.571,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.168804,0.0012874,0.878864 beta-lactamase_0_E169R,beta-lactamase_0_169,TEM-1,beta-lactamase_0,P62593,0.878867,NO,169,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.23,-3.638,2.408,,0.337,,A,1.04,1,3.516,,73.08,PAH,-1.16533,0.0500837,0.00400994,0.878867 kka2_1:4_F203W,kka2_1:4_203,Kka2,kka2_1:4,P00552,0.878884,NO,203,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-0.911,-4.558,3.647,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.168804,0.00318738,0.878884 beta-lactamase_0_D231I,beta-lactamase_0_231,TEM-1,beta-lactamase_0,P62593,0.878894,NO,231,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.816,-4.036,3.22,,,E,B,0.75,-1.06,4.975,,65.38,HAB,-0.994,0.0500837,0.00107395,0.878894 beta-lactamase_2500_D99T,beta-lactamase_2500_99,TEM-1,beta-lactamase_2500,P62593,0.878903,NO,99,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.191,-3.531,2.34,,0.402,G,A,0.75,0.36,1.318,,64.69,PAH,-1.794,0.361275,0.00305446,0.878903 beta-lactamase_39_I45D,beta-lactamase_39_45,TEM-1,beta-lactamase_39,P62593,0.878921,NO,45,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-2.421,-3.902,1.481,,,E,B,0.48,-0.3,2.256,,77.62,HHA,-2.30267,0.0495842,0.00452842,0.878921 beta-lactamase_V21G,beta-lactamase_21,TEM-1,beta-lactamase,P62593,0.878968,NO,21,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.873,-3.266,1.393,,,,,,,0.688,,93.01,OHH,-2.09633,0.221079,0.0028612,0.878968 kka2_1:4_L174T,kka2_1:4_174,Kka2,kka2_1:4,P00552,0.878994,NO,174,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.952,-3.474,2.522,,,H,A,0.55,-0.31,1.339,,51.89,BHB,-2.08533,0.168804,0.00438501,0.878994 kka2_1:4_T125F,kka2_1:4_125,Kka2,kka2_1:4,P00552,0.879029,NO,125,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.622,-4.443,1.821,,0.791,T,A,0.82,0.33,1.612,,92.05,BPH,-1.56933,0.168804,0.00821755,0.879029 Ubiquitin_D24F,Ubiquitin_24,Uba1,Ubiquitin,P0CG48,0.879032,NO,24,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,,,,,,,,,,,,,HAP,,0.205827,0.0066591,0.879032 Ubiquitin_D39W,Ubiquitin_39,Uba1,Ubiquitin,P0CG48,0.879032,NO,39,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.792,-5.408,3.616,5.1607,0.433,G,A,,0.55,,,,OAP,-1.754,0.205827,0.00071409,0.879032 Ubiquitin_D58W,Ubiquitin_58,Uba1,Ubiquitin,P0CG48,0.879032,NO,58,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.622,-5.306,3.684,5.06391,0.457,G,A,,-0.54,,,,PAH,-1.60267,0.205827,0.000639847,0.879032 Ubiquitin_E34T,Ubiquitin_34,Uba1,Ubiquitin,P0CG48,0.879032,NO,34,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.294,-3.498,2.204,5.02178,0.406,H,A,1.62,0.6,1.295,,35.62,BAO,-1.24933,0.205827,0.000686048,0.879032 Ubiquitin_E51P,Ubiquitin_51,Uba1,Ubiquitin,P0CG48,0.879032,NO,51,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.534,-2.801,1.267,5.36711,0.545,,B,,0.72,,,,HAA,-1.357,0.205827,0.000868134,0.879032 Ubiquitin_F45L,Ubiquitin_45,Uba1,Ubiquitin,P0CG48,0.879032,NO,45,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.322,-2.177,0.855,4.80693,0.26,E,B,1.62,-0.99,1.531,,53.87,HHH,-1.55267,0.205827,0.000470401,0.879032 Ubiquitin_I13A,Ubiquitin_13,Uba1,Ubiquitin,P0CG48,0.879032,NO,13,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.554,-3.174,1.62,5.19411,0.038,E,B,,-0.2,,,,PHP,-1.48,0.205827,0.000716423,0.879032 Ubiquitin_I13K,Ubiquitin_13,Uba1,Ubiquitin,P0CG48,0.879032,NO,13,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.554,-2.829,1.275,5.19411,0.038,E,B,,-0.2,,,,PHP,-1.48,0.205827,0.000716423,0.879032 Ubiquitin_K6N,Ubiquitin_6,Uba1,Ubiquitin,P0CG48,0.879032,NO,6,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.093,-3.461,2.368,4.84211,0.35,E,B,1.82,-0.62,1.502,,71.82,HBP,-1.36133,0.205827,0.000784795,0.879032 Ubiquitin_Q40I,Ubiquitin_40,Uba1,Ubiquitin,P0CG48,0.879032,NO,40,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-1.752,-3.034,1.282,4.7807,0.387,G,A,,0.03,,,,APP,-1.62433,0.205827,0.000619089,0.879032 Ubiquitin_V5Y,Ubiquitin_5,Uba1,Ubiquitin,P0CG48,0.879032,NO,5,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.576,-4.086,2.51,4.75677,,E,B,,-0.82,,,,HHB,-1.401,0.205827,0.000796998,0.879032 beta-lactamase_E87Q,beta-lactamase_87,TEM-1,beta-lactamase,P62593,0.879082,NO,87,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.421,-2.648,1.227,5.41929,0.048,,B,0.52,0.92,1.754,,64.69,PAP,-1.969,0.221079,0.00337888,0.879082 beta-lactamase_0_L218N,beta-lactamase_0_218,TEM-1,beta-lactamase_0,P62593,0.879093,NO,218,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.391,-3.851,2.46,,,I,b,0.55,-0.53,28.707,28.707,74.48,OHH,-1.58867,0.0500837,0.00618274,0.879093 beta-lactamase_0_H287G,beta-lactamase_0_287,TEM-1,beta-lactamase_0,P62593,0.879131,NO,287,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,,,,,,,,,,,,,BBH,-1.111,0.0500837,,0.879131 beta-lactamase_2500_R202C,beta-lactamase_2500_202,TEM-1,beta-lactamase_2500,P62593,0.879213,NO,202,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.292,-5.047,3.755,,0.188,H,A,1.2,0.62,3.734,,77.62,PBP,-1.54767,0.361275,0.00321899,0.879213 beta-lactamase_0_V106S,beta-lactamase_0_106,TEM-1,beta-lactamase_0,P62593,0.879236,NO,106,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.218,-3.705,2.487,,0.258,T,A,0.44,0.24,0.952,,72.73,OHP,-1.04933,0.0500837,0.00304168,0.879236 kka2_1:8_Q27H,kka2_1:8_27,Kka2,kka2_1:8,P00552,0.87925,NO,27,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-1.659,-4.651,2.992,,0.608,.,A,0.64,0.71,3.919,,65.53,PPP,-1.90733,0.100394,0.00595365,0.87925 kka2_1:8_Q27H,kka2_1:8_27,Kka2,kka2_1:8,P00552,0.87925,NO,27,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-1.659,-4.651,2.992,,0.608,.,A,0.64,0.71,3.919,,65.53,PPP,-1.90733,0.100394,0.00595365,0.87925 kka2_1:4_L223V,kka2_1:4_223,Kka2,kka2_1:4,P00552,0.879263,NO,223,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.861,-2.827,1.966,,,H,A,1.59,-1.24,1.268,,50,HHH,-0.854333,0.168804,0.00253574,0.879263 kka2_1:4_E182T,kka2_1:4_182,Kka2,kka2_1:4,P00552,0.87932,NO,182,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.516,-2.525,1.009,,0.326,.,B,1.04,0.75,4.755,,65.53,OAA,-1.806,0.168804,0.00641548,0.87932 beta-lactamase_0_D252A,beta-lactamase_0_252,TEM-1,beta-lactamase_0,P62593,0.879338,NO,252,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.0500837,0.00575769,0.879338 beta-lactamase_0_L196M,beta-lactamase_0_196,TEM-1,beta-lactamase_0,P62593,0.879389,NO,196,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-2.478,-3.442,0.964,,0.518,S,A,0.55,1.35,6.513,6.513,77.62,AHH,-1.839,0.0500837,0.00512144,0.879389 beta-lactamase_2500_K213C,beta-lactamase_2500_213,TEM-1,beta-lactamase_2500,P62593,0.879414,NO,213,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.81,-5.208,3.398,,0.67,,A,2.34,0.29,1.668,,67.83,ABH,-1.57767,0.361275,0.00610411,0.879414 beta-lactamase_0_A148D,beta-lactamase_0_148,TEM-1,beta-lactamase_0,P62593,0.879492,NO,148,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.757,-2.341,0.584,,0.379,H,A,0.46,-0.55,19.42,19.42,72.73,PHH,-1.40167,0.0500837,0.00547053,0.879492 beta-lactamase_0_L137N,beta-lactamase_0_137,TEM-1,beta-lactamase_0,P62593,0.879526,NO,137,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.03,-4.152,3.122,,,H,A,0.55,-0.38,0.328,,42.31,HHP,-1.58933,0.0500837,0.00278599,0.879526 WW_domain_R187D,WW_domain_187,Yap65,WW_domain,P46937,0.879576,NO,187,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.402,-3.464,2.062,5.05189,,,,,,3.431,,78.57,PBH,-1.362,0.153962,0.00171149,0.879576 kka2_1:2_S104R,kka2_1:2_104,Kka2,kka2_1:2,P00552,0.879662,NO,104,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.436,-3.063,1.627,,0.536,T,A,0.27,-1.11,5.49,,63.64,HPP,-1.91433,0.295029,0.00555207,0.879662 Pab1_V148D,Pab1_148,Pab1,Pab1,P04147,0.879662,NO,148,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.875,-3.58,1.705,,,,,,,,,,PHH,-1.43033,0.175299,0.00179641,0.879662 beta-lactamase_E270Y,beta-lactamase_270,TEM-1,beta-lactamase,P62593,0.879708,NO,270,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.723,-4.335,2.612,5.33196,0.422,H,A,0.52,1.15,1.745,,64.34,AAB,-1.70933,0.221079,0.00767762,0.879708 beta-lactamase_F14S,beta-lactamase_14,TEM-1,beta-lactamase,P62593,0.879708,NO,14,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-2.736,-3.559,0.823,,,,,,,1.537,,93.01,HHH,-2.26133,0.221079,0.00277095,0.879708 beta-lactamase_G52N,beta-lactamase_52,TEM-1,beta-lactamase,P62593,0.879708,NO,52,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.149,-3.58,2.431,5.12093,0.299,,l,0.77,-0.04,2.103,,64.69,POB,-1.66267,0.221079,0.00340138,0.879708 kka2_1:8_R38E,kka2_1:8_38,Kka2,kka2_1:8,P00552,0.879712,NO,38,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.207,-3.518,2.311,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.100394,0.00372499,0.879712 kka2_1:8_R38E,kka2_1:8_38,Kka2,kka2_1:8,P00552,0.879712,NO,38,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.207,-3.518,2.311,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.100394,0.00372499,0.879712 kka2_1:8_W236R,kka2_1:8_236,Kka2,kka2_1:8,P00552,0.879724,NO,236,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-1.363,-4.21,2.847,,0.303,H,A,1.51,-0.76,1.87,,48.48,AHH,-1.81267,0.100394,0.0088796,0.879724 kka2_1:8_W236R,kka2_1:8_236,Kka2,kka2_1:8,P00552,0.879724,NO,236,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-1.363,-4.21,2.847,,0.303,H,A,1.51,-0.76,1.87,,48.48,AHH,-1.81267,0.100394,0.0088796,0.879724 beta-lactamase_0_P60C,beta-lactamase_0_60,TEM-1,beta-lactamase_0,P62593,0.879725,NO,60,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-2.469,-4.889,2.42,,0.256,T,A,0.52,-0.56,3.653,,77.62,BOA,-1.97633,0.0500837,0.00521318,0.879725 beta-lactamase_R271G,beta-lactamase_271,TEM-1,beta-lactamase,P62593,0.879823,NO,271,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.249,-3.515,2.266,5.24516,0.085,H,A,1.67,-0.05,0.474,,63.99,ABP,-1.36633,0.221079,0.00752082,0.879823 Pab1_L186R,Pab1_186,Pab1,Pab1,P04147,0.879837,NO,186,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.783,-4.042,2.259,,,,,,,,,,HHP,-1.56967,0.175299,0.00154968,0.879837 kka2_1:2_R18L,kka2_1:2_18,Kka2,kka2_1:2,P00552,0.879846,NO,18,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.055,-2.54,0.485,,0.474,T,A,1.2,0.54,8.405,8.405,71.59,ABH,-1.821,0.295029,0.00724065,0.879846 gb1_A250R,gb1_250,gb1,gb1,P06654,0.879872,NO,250,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.713,-2.222,0.509,,,,,,,3.465,,45.54,HHP,-1.74867,0.177985,0.00332003,0.879872 beta-lactamase_0_N50Q,beta-lactamase_0_50,TEM-1,beta-lactamase_0,P62593,0.879905,NO,50,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-2.979,-2.653,-0.326,,0.912,T,A,0.61,1.24,9.874,9.874,77.62,HPP,-2.134,0.0500837,0.0047211,0.879905 beta-lactamase_0_P105Q,beta-lactamase_0_105,TEM-1,beta-lactamase_0,P62593,0.879937,NO,105,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.813,-3.897,3.084,,0.226,T,A,0.52,0.8,3.48,,63.29,POH,-1.01533,0.0500837,0.0011981,0.879937 PSD95pdz3_V328T,PSD95pdz3_328,PSD95pdz3,PSD95pdz3,P31016,0.880003,NO,328,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.465,-2.878,1.413,5.28275,,,,,16.8775,,,,HHO,-1.36767,0.0758425,0.000986706,0.880003 beta-lactamase_0_S122H,beta-lactamase_0_122,TEM-1,beta-lactamase_0,P62593,0.880017,NO,122,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.406,-2.676,0.27,,0.352,H,A,0.27,-0.54,30.794,30.794,77.62,OPH,-1.39767,0.0500837,0.00497825,0.880017 Pab1_L186K,Pab1_186,Pab1,Pab1,P04147,0.880027,NO,186,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.783,-3.697,1.914,,,,,,,,,,HHP,-1.56967,0.175299,0.00154968,0.880027 beta-lactamase_0_L218A,beta-lactamase_0_218,TEM-1,beta-lactamase_0,P62593,0.880043,NO,218,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.391,-3.175,1.784,,,I,b,0.55,-0.53,28.707,28.707,74.48,OHH,-1.58867,0.0500837,0.00618274,0.880043 kka2_1:4_P98D,kka2_1:4_98,Kka2,kka2_1:4,P00552,0.880047,NO,98,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.526,-2.576,1.05,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.168804,0.00622754,0.880047 beta-lactamase_0_G141S,beta-lactamase_0_141,TEM-1,beta-lactamase_0,P62593,0.880132,NO,141,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.828,-3.221,2.393,,0.575,T,l,0.29,-0.28,0.722,,64.69,HOO,-1.08933,0.0500837,0.0012419,0.880132 kka2_1:2_V49M,kka2_1:2_49,Kka2,kka2_1:2,P00552,0.880167,NO,49,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.614,-4.13,2.516,,,E,B,0.44,-0.77,1.233,,64.39,HHB,-1.3,0.295029,0.00615685,0.880167 beta-lactamase_T147I,beta-lactamase_147,TEM-1,beta-lactamase,P62593,0.880187,NO,147,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.149,-2.792,1.643,5.37474,0.281,H,A,0.8,-0.68,2.838,,64.34,HPH,-1.456,0.221079,0.00226017,0.880187 Pab1_A141Y,Pab1_141,Pab1,Pab1,P04147,0.880197,NO,141,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.461,-4.09,2.629,,0.34,H,A,0.52,-0.27,2.15,,79.03,BHH,-1.19433,0.175299,0.00165974,0.880197 kka2_1:4_V185C,kka2_1:4_185,Kka2,kka2_1:4,P00552,0.880228,NO,185,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.045,-3.114,2.069,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.168804,0.00367031,0.880228 Pab1_V148G,Pab1_148,Pab1,Pab1,P04147,0.880262,NO,148,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.875,-3.165,1.29,,,,,,,,,,PHH,-1.43033,0.175299,0.00179641,0.880262 Pab1_N139I,Pab1_139,Pab1,Pab1,P04147,0.880314,NO,139,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-1.079,-3.827,2.748,,0.062,H,A,,-0.73,,,,APB,-1.09667,0.175299,0.000339145,0.880314 PSD95pdz3_S339P,PSD95pdz3_339,PSD95pdz3,PSD95pdz3,P31016,0.880315,NO,339,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.519,-3.336,1.817,5.34493,,,,,12.2167,,,,HPH,-1.55767,0.0758425,0.00084982,0.880315 beta-lactamase_0_E46D,beta-lactamase_0_46,TEM-1,beta-lactamase_0,P62593,0.880338,NO,46,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.94,-3.652,1.712,,0.021,E,B,1.04,0.14,30.306,30.306,59.44,HAH,-2.079,0.0500837,0.00427568,0.880338 beta-lactamase_156_D174Y,beta-lactamase_156_174,TEM-1,beta-lactamase_156,P62593,0.880347,NO,174,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.738,-4.387,3.649,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.111618,0.00125633,0.880347 beta-lactamase_0_L146A,beta-lactamase_0_146,TEM-1,beta-lactamase_0,P62593,0.880377,NO,146,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.462,-3.204,1.742,,0.007,H,A,0.55,-0.56,2.051,,64.69,AHP,-1.656,0.0500837,0.00474542,0.880377 beta-lactamase_625_K30E,beta-lactamase_625_30,TEM-1,beta-lactamase_625,P62593,0.880384,NO,30,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-2.307,-2.686,0.379,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.213352,0.00448593,0.880384 beta-lactamase_0_G265F,beta-lactamase_0_265,TEM-1,beta-lactamase_0,P62593,0.880394,NO,265,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.0500837,0.00811926,0.880394 beta-lactamase_2500_K30I,beta-lactamase_2500_30,TEM-1,beta-lactamase_2500,P62593,0.880421,NO,30,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-2.307,-3.856,1.549,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.361275,0.00448593,0.880421 beta-lactamase_39_G43T,beta-lactamase_39_43,TEM-1,beta-lactamase_39,P62593,0.880421,NO,43,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.62,-3.646,3.026,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.0495842,0.00120151,0.880421 beta-lactamase_L55E,beta-lactamase_55,TEM-1,beta-lactamase,P62593,0.880448,NO,55,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.86,-3.84,1.98,,0.372,E,A,1.07,-0.36,1.423,,63.99,HHA,-2.247,0.221079,0.00403741,0.880448 kka2_1:2_E160T,kka2_1:2_160,Kka2,kka2_1:2,P00552,0.880456,NO,160,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.683,-3.562,1.879,,0.989,G,A,1.04,2.28,3.948,,71.59,AAA,-1.36133,0.295029,0.00935762,0.880456 beta-lactamase_0_G85S,beta-lactamase_0_85,TEM-1,beta-lactamase_0,P62593,0.880484,NO,85,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.011,-3.264,2.253,,0.805,T,l,0.29,1.7,2.25,,63.64,HOP,-1.68733,0.0500837,0.00252173,0.880484 kka2_1:1_W24L,kka2_1:1_24,Kka2,kka2_1:1,P00552,0.880491,NO,24,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-1.779,-2.533,0.754,,0.477,E,B,0.47,-0.21,2.375,,56.06,AHH,-2.24467,0.520039,0.00631564,0.880491 kka2_1:2_G151C,kka2_1:2_151,Kka2,kka2_1:2,P00552,0.880515,NO,151,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.873,-5.156,4.283,,0.678,T,l,0.29,1.36,1.357,,49.62,HOH,-1.11433,0.295029,0.00339918,0.880515 beta-lactamase_39_E272N,beta-lactamase_39_272,TEM-1,beta-lactamase_39,P62593,0.880538,NO,272,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.127,-2.497,1.37,,0.081,H,A,0.43,-0.97,12.983,12.983,63.64,AAB,-1.56333,0.0495842,0.00545371,0.880538 beta-lactamase_0_R91F,beta-lactamase_0_91,TEM-1,beta-lactamase_0,P62593,0.880606,NO,91,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.392,-4.376,2.984,,0.444,,B,1.2,0.96,4.557,,50.35,OBB,-1.73367,0.0500837,0.00380226,0.880606 beta-lactamase_D113L,beta-lactamase_113,TEM-1,beta-lactamase,P62593,0.880613,NO,113,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.829,-3.651,1.822,6.04499,0.665,T,A,0.23,0.91,21.104,21.104,73.08,PAO,-1.703,0.221079,0.00474112,0.880613 beta-lactamase_0_T187S,beta-lactamase_0_187,TEM-1,beta-lactamase_0,P62593,0.880633,NO,187,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.401,-2.134,0.733,,0.007,H,A,0.22,-1.19,3.259,,67.48,PPH,-1.69633,0.0500837,0.00491782,0.880633 beta-lactamase_C121A,beta-lactamase_121,TEM-1,beta-lactamase,P62593,0.880655,NO,121,C,A,CA,Special,Hydrophobic,5.07,6,0.93,195,121,89,-32,108.5,88.6,-19.9,-0.953,-2.902,1.949,5.12205,,H,A,2.8,-0.81,7.644,,63.29,HOP,-1.46767,0.221079,0.000744322,0.880655 beta-lactamase_S281G,beta-lactamase_281,TEM-1,beta-lactamase,P62593,0.880752,NO,281,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.247,-3.28,1.033,4.73591,0.128,H,A,0.25,-0.26,2.144,,77.62,HPH,-1.847,0.221079,0.0406482,0.880752 beta-lactamase_A77G,beta-lactamase_77,TEM-1,beta-lactamase,P62593,0.880762,NO,77,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.234,-2.31,1.076,4.75777,0.039,H,A,0.52,-0.56,1.708,,64.34,OHH,-1.294,0.221079,0.00282362,0.880762 beta-lactamase_A124C,beta-lactamase_124,TEM-1,beta-lactamase,P62593,0.880784,NO,124,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.181,-4.594,3.413,4.58507,,H,A,0.58,-0.9,2.273,,64.34,HHH,-1.152,0.221079,0.00481399,0.880784 beta-lactamase_0_R159L,beta-lactamase_0_159,TEM-1,beta-lactamase_0,P62593,0.880836,NO,159,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-0.94,-3.407,2.467,,0.316,,B,1.2,-0.55,1.426,,64.34,PBH,-1.011,0.0500837,0.00108472,0.880836 beta-lactamase_0_S80L,beta-lactamase_0_80,TEM-1,beta-lactamase_0,P62593,0.880859,NO,80,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.029,-2.857,0.828,,0.192,H,A,0.27,0.46,12.403,12.403,77.62,HPB,-1.44567,0.0500837,0.00565569,0.880859 kka2_1:1_A13Q,kka2_1:1_13,Kka2,kka2_1:1,P00552,0.88088,NO,13,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.248,-3.029,0.781,,0.689,G,A,0.46,0.99,25.015,25.015,92.05,OHH,-1.646,0.520039,0.00784241,0.88088 kka2_1:8_E59L,kka2_1:8_59,Kka2,kka2_1:8,P00552,0.880907,NO,59,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-0.952,-3.625,2.673,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.100394,0.00280355,0.880907 kka2_1:8_E59L,kka2_1:8_59,Kka2,kka2_1:8,P00552,0.880907,NO,59,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-0.952,-3.625,2.673,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.100394,0.00280355,0.880907 beta-lactamase_0_L199G,beta-lactamase_0_199,TEM-1,beta-lactamase_0,P62593,0.88091,NO,199,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-2.942,-2.663,-0.279,,0.832,H,A,0.55,0.42,10.85,10.85,77.62,PHH,-2.32933,0.0500837,0.0048649,0.88091 PSD95pdz3_G330E,PSD95pdz3_330,PSD95pdz3,PSD95pdz3,P31016,0.880944,NO,330,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.008,-3.347,2.339,4.68351,,,,,31.405,,,,OOA,-1.14,0.0758425,0.000962386,0.880944 beta-lactamase_39_L47D,beta-lactamase_39_47,TEM-1,beta-lactamase_39,P62593,0.88095,NO,47,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.876,-3.931,2.055,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.0495842,0.00439844,0.88095 beta-lactamase_G216R,beta-lactamase_216,TEM-1,beta-lactamase,P62593,0.880955,NO,216,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.477,-2.93,1.453,4.91694,0.437,I,A,0.23,-0.58,1.718,,74.48,HOO,-1.68067,0.221079,0.00639568,0.880955 beta-lactamase_0_D177C,beta-lactamase_0_177,TEM-1,beta-lactamase_0,P62593,0.880974,NO,177,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.967,-5.073,4.106,,0.006,T,L,0.75,-1.02,3.536,,64.69,BAP,-0.873667,0.0500837,0.000864022,0.880974 kka2_1:1_R239T,kka2_1:1_239,Kka2,kka2_1:1,P00552,0.881,NO,239,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.949,-3.616,0.667,,0.15,H,A,1.2,-0.31,0.477,,71.59,ABH,-2.23,0.520039,0.00835326,0.881 beta-lactamase_0_Q97T,beta-lactamase_0_97,TEM-1,beta-lactamase_0,P62593,0.881021,NO,97,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.072,-2.713,0.641,,0.823,G,A,0.64,2.42,16.954,16.954,77.62,PPP,-2.43833,0.0500837,0.0045116,0.881021 beta-lactamase_0_T69R,beta-lactamase_0_69,TEM-1,beta-lactamase_0,P62593,0.881042,NO,69,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-0.973,-3.768,2.795,,,G,A,0.22,-1.24,0.505,,93.01,PPH,-1.01833,0.0500837,0.00127498,0.881042 beta-lactamase_0_L146I,beta-lactamase_0_146,TEM-1,beta-lactamase_0,P62593,0.881126,NO,146,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.462,-2.631,1.169,,0.007,H,A,0.55,-0.56,2.051,,64.69,AHP,-1.656,0.0500837,0.00474542,0.881126 WW_domain_Q186G,WW_domain_186,Yap65,WW_domain,P46937,0.881133,NO,186,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-1.358,-3.135,1.777,4.88854,,,,,,,,,OPB,-1.207,0.153962,0.00161546,0.881133 kka2_1:8_Q100P,kka2_1:8_100,Kka2,kka2_1:8,P00552,0.881213,NO,100,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.77,-4.125,1.355,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.100394,0.0066405,0.881213 kka2_1:8_Q100P,kka2_1:8_100,Kka2,kka2_1:8,P00552,0.881213,NO,100,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.77,-4.125,1.355,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.100394,0.0066405,0.881213 beta-lactamase_0_P143Q,beta-lactamase_0_143,TEM-1,beta-lactamase_0,P62593,0.881261,NO,143,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.967,-4.024,3.057,,0.075,H,A,0.52,-0.37,11.868,11.868,66.78,OOB,-1.354,0.0500837,0.00114551,0.881261 beta-lactamase_39_T193P,beta-lactamase_39_193,TEM-1,beta-lactamase_39,P62593,0.881263,NO,193,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.914,-4.072,2.158,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.0495842,0.00482669,0.881263 beta-lactamase_E62N,beta-lactamase_62,TEM-1,beta-lactamase,P62593,0.881337,NO,62,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.193,-3.541,2.348,5.93066,0.342,S,B,1.52,-0.3,3.139,,73.08,AAB,-1.417,0.221079,0.00264802,0.881337 beta-lactamase_F228K,beta-lactamase_228,TEM-1,beta-lactamase,P62593,0.881337,NO,228,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-2.342,-2.864,0.522,5.33448,0.154,E,B,1.1,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.221079,0.0046669,0.881337 beta-lactamase_R7E,beta-lactamase_7,TEM-1,beta-lactamase,P62593,0.881337,NO,7,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.683,-3.419,1.736,,,,,,,2.44,,67.13,HBH,-1.96267,0.221079,0.00211375,0.881337 kka2_1:2_R239Y,kka2_1:2_239,Kka2,kka2_1:2,P00552,0.881347,NO,239,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.949,-4.327,1.378,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.295029,0.00835326,0.881347 beta-lactamase_0_N134K,beta-lactamase_0_134,TEM-1,beta-lactamase_0,P62593,0.881348,NO,134,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-0.879,-2.445,1.566,,0.138,H,A,0.61,-0.6,3.776,,53.15,HPH,-1.02233,0.0500837,0.000644786,0.881348 Pab1_Y197Q,Pab1_197,Pab1,Pab1,P04147,0.881383,NO,197,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-1.345,-3.966,2.621,,,,,,,0.891,,80.42,HHH,-1.41767,0.175299,0.00302474,0.881383 beta-lactamase_R176L,beta-lactamase_176,TEM-1,beta-lactamase,P62593,0.881386,NO,176,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-0.863,-3.358,2.495,5.61264,0.385,T,B,0.68,-0.63,,,,ABA,-1.38867,0.221079,0.00105554,0.881386 beta-lactamase_39_N168Y,beta-lactamase_39_168,TEM-1,beta-lactamase_39,P62593,0.8814,NO,168,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-1.029,-4.205,3.176,,0.113,G,A,0.61,-0.4,0.822,,44.41,HPA,-1.13233,0.0495842,0.00288667,0.8814 kka2_1:4_Y244H,kka2_1:4_244,Kka2,kka2_1:4,P00552,0.881453,NO,244,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-0.775,-3.808,3.033,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.168804,0.00453187,0.881453 kka2_1:4_Q4H,kka2_1:4_4,Kka2,kka2_1:4,P00552,0.881467,NO,4,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.361,-4.16,1.799,,,,,,,2.026,,71.59,APA,-1.95533,0.168804,0.00239179,0.881467 beta-lactamase_H110L,beta-lactamase_110,TEM-1,beta-lactamase,P62593,0.881469,NO,110,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-1.706,-3.515,1.809,5.52635,0.341,G,a,0.35,1.08,31.31,31.31,64.69,BBH,-1.73333,0.221079,0.00441499,0.881469 beta-lactamase_0_S68F,beta-lactamase_0_68,TEM-1,beta-lactamase_0,P62593,0.881487,NO,68,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-0.913,-4.116,3.203,,0.064,G,A,0.27,-1.03,1.441,,64.69,HPP,-1.37233,0.0500837,0.000800065,0.881487 beta-lactamase_0_L218S,beta-lactamase_0_218,TEM-1,beta-lactamase_0,P62593,0.88151,NO,218,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.391,-2.79,1.399,,,I,b,0.55,-0.53,28.707,28.707,74.48,OHH,-1.58867,0.0500837,0.00618274,0.88151 gb1_Y259M,gb1_259,gb1,gb1,P06654,0.881561,NO,259,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-1.78,-4.255,2.475,,,,,,,0.131,,11.83,PHH,-1.787,0.177985,0.00464313,0.881561 WW_domain_Q186E,WW_domain_186,Yap65,WW_domain,P46937,0.881611,NO,186,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-1.358,-2.542,1.184,4.88854,,,,,,,,,OPB,-1.207,0.153962,0.00161546,0.881611 beta-lactamase_156_M209W,beta-lactamase_156_209,TEM-1,beta-lactamase_156,P62593,0.881656,NO,209,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.442,-4.979,3.537,,,H,A,0.55,-0.97,1.066,,64.69,HHA,-1.52633,0.111618,0.00625021,0.881656 kka2_1:8_R145L,kka2_1:8_145,Kka2,kka2_1:8,P00552,0.881661,NO,145,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.804,-3.61,1.806,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.100394,0.00846663,0.881661 kka2_1:8_R145L,kka2_1:8_145,Kka2,kka2_1:8,P00552,0.881661,NO,145,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.804,-3.61,1.806,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.100394,0.00846663,0.881661 kka2_1:2_L39V,kka2_1:2_39,Kka2,kka2_1:2,P00552,0.881678,NO,39,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.223,-2.08,0.857,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.295029,0.00493618,0.881678 beta-lactamase_0_L160R,beta-lactamase_0_160,TEM-1,beta-lactamase_0,P62593,0.881785,NO,160,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.977,-4.03,3.053,,0.022,,B,0.55,-0.6,0.68,,44.41,BHA,-0.936,0.0500837,0.00193775,0.881785 beta-lactamase_0_A185G,beta-lactamase_0_185,TEM-1,beta-lactamase_0,P62593,0.881809,NO,185,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.406,-3.37,1.964,,,H,A,0.46,-1.02,1.203,,65.03,HHP,-1.84033,0.0500837,0.00467449,0.881809 beta-lactamase_2500_M180D,beta-lactamase_2500_180,TEM-1,beta-lactamase_2500,P62593,0.881813,NO,180,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-2.795,-3.594,0.799,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.361275,0.00552048,0.881813 Pab1_S155Y,Pab1_155,Pab1,Pab1,P04147,0.881831,NO,155,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.039,-4.05,2.011,,,,,,,,,,PPB,-1.42267,0.175299,0.00208179,0.881831 beta-lactamase_L111S,beta-lactamase_111,TEM-1,beta-lactamase,P62593,0.881851,NO,111,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.76,-3.564,1.804,5.8705,0.328,T,A,0.84,0.93,3.836,,64.34,BHP,-1.884,0.221079,0.00480671,0.881851 kka2_1:8_R89S,kka2_1:8_89,Kka2,kka2_1:8,P00552,0.881873,NO,89,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.548,-3.512,1.964,,0.209,E,B,1.2,1.41,25.3,25.3,64.39,OBA,-1.89867,0.100394,0.00524373,0.881873 kka2_1:8_R89S,kka2_1:8_89,Kka2,kka2_1:8,P00552,0.881873,NO,89,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.548,-3.512,1.964,,0.209,E,B,1.2,1.41,25.3,25.3,64.39,OBA,-1.89867,0.100394,0.00524373,0.881873 beta-lactamase_0_S266I,beta-lactamase_0_266,TEM-1,beta-lactamase_0,P62593,0.881876,NO,266,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.0500837,0.0140785,0.881876 PSD95pdz3_I336C,PSD95pdz3_336,PSD95pdz3,PSD95pdz3,P31016,0.881885,NO,336,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.63,-4.319,2.689,5.11321,,,,,13.6363,,,,OHH,-1.38733,0.0758425,0.000887923,0.881885 beta-lactamase_0_P224D,beta-lactamase_0_224,TEM-1,beta-lactamase_0,P62593,0.881889,NO,224,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.893,-3.513,2.62,,0.383,,B,0.52,-0.3,3.587,,74.48,HOH,-1.26433,0.0500837,0.00189564,0.881889 beta-lactamase_0_D33G,beta-lactamase_0_33,TEM-1,beta-lactamase_0,P62593,0.88192,NO,33,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.321,-3.465,1.144,,0.366,H,A,0.75,0.33,12.514,12.514,77.62,BAH,-2.12133,0.0500837,0.00435556,0.88192 beta-lactamase_625_E87G,beta-lactamase_625_87,TEM-1,beta-lactamase_625,P62593,0.881933,NO,87,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.421,-3.541,2.12,,0.048,,B,1.04,0.92,17.923,17.923,64.69,PAP,-1.969,0.213352,0.00337888,0.881933 beta-lactamase_D99R,beta-lactamase_99,TEM-1,beta-lactamase,P62593,0.881969,NO,99,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.191,-3.828,2.637,5.66081,0.402,G,A,0.23,0.36,1.318,,64.69,PAH,-1.794,0.221079,0.00305446,0.881969 beta-lactamase_2500_L49A,beta-lactamase_2500_49,TEM-1,beta-lactamase_2500,P62593,0.881976,NO,49,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.897,-3.125,1.228,,0.131,T,A,0.55,0.04,6.681,,64.69,AHP,-1.99233,0.361275,0.00401477,0.881976 beta-lactamase_0_K213S,beta-lactamase_0_213,TEM-1,beta-lactamase_0,P62593,0.881998,NO,213,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.81,-3.351,1.541,,0.67,,A,2.34,0.29,3.015,,67.83,ABH,-1.57767,0.0500837,0.00610411,0.881998 beta-lactamase_0_L284V,beta-lactamase_0_284,TEM-1,beta-lactamase_0,P62593,0.882051,NO,284,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.981,,,,0.848,H,A,2.89,0.67,4.544,,77.62,PHH,-1.82133,0.0500837,0.0686156,0.882051 PSD95pdz3_L367C,PSD95pdz3_367,PSD95pdz3,PSD95pdz3,P31016,0.88206,NO,367,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.347,-4.319,2.972,5.47696,,,,,17.0063,,,,AHB,-1.39767,0.0758425,0.000466436,0.88206 beta-lactamase_39_V72Q,beta-lactamase_39_72,TEM-1,beta-lactamase_39,P62593,0.882065,NO,72,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.658,-4.185,2.527,,,H,A,0.44,-1.03,1.92,,65.73,BHH,-1.32167,0.0495842,0.00501194,0.882065 beta-lactamase_0_L205N,beta-lactamase_0_205,TEM-1,beta-lactamase_0,P62593,0.882066,NO,205,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.922,-4.141,3.219,,,H,A,0.55,-0.46,1.065,,42.31,PHH,-1.57767,0.0500837,0.00255802,0.882066 kka2_1:2_Q252V,kka2_1:2_252,Kka2,kka2_1:2,P00552,0.882115,NO,252,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.63,-3.102,0.472,,0.906,H,A,0.64,0.35,5.613,,92.05,PPB,-2.20733,0.295029,0.0121001,0.882115 beta-lactamase_0_A40M,beta-lactamase_0_40,TEM-1,beta-lactamase_0,P62593,0.88219,NO,40,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.402,-4.684,3.282,,0.155,S,B,0.46,0.21,0.783,,73.78,OHB,-1.40267,0.0500837,0.00490026,0.88219 beta-lactamase_I54S,beta-lactamase_54,TEM-1,beta-lactamase,P62593,0.882253,NO,54,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-2.838,-3.459,0.621,5.40541,0.669,E,B,0.77,-0.14,3.946,,73.78,BHH,-2.337,0.221079,0.00403589,0.882253 beta-lactamase_0_S96Q,beta-lactamase_0_96,TEM-1,beta-lactamase_0,P62593,0.882285,NO,96,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.27,-2.919,0.649,,0.368,,b,0.27,0.39,2.516,,73.78,HPP,-2.019,0.0500837,0.00551835,0.882285 kka2_1:2_D33C,kka2_1:2_33,Kka2,kka2_1:2,P00552,0.88235,NO,33,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.186,-5.16,2.974,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.295029,0.00633568,0.88235 beta-lactamase_2500_P255N,beta-lactamase_2500_255,TEM-1,beta-lactamase_2500,P62593,0.882382,NO,255,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.361275,0.00499612,0.882382 beta-lactamase_0_V259S,beta-lactamase_0_259,TEM-1,beta-lactamase_0,P62593,0.88241,NO,259,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.0500837,0.0070773,0.88241 beta-lactamase_L28C,beta-lactamase_28,TEM-1,beta-lactamase,P62593,0.882423,NO,28,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.579,-4.763,3.184,5.42969,0.277,H,A,0.07,-0.16,19.748,19.748,93.01,PHH,-2.11333,0.221079,0.00359321,0.882423 beta-lactamase_M153E,beta-lactamase_153,TEM-1,beta-lactamase,P62593,0.882423,NO,153,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-3.193,-3.818,0.625,5.46509,0.14,T,A,1.07,-0.11,2.061,,77.62,PHO,-2.25767,0.221079,0.00509109,0.882423 beta-lactamase_S2V,beta-lactamase_2,TEM-1,beta-lactamase,P62593,0.882423,NO,2,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.942,-2.088,0.146,,,,,,,2.36,,65.38,HPH,-2.02767,0.221079,0.00227352,0.882423 beta-lactamase_T27C,beta-lactamase_27,TEM-1,beta-lactamase,P62593,0.882423,NO,27,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.905,-4.927,3.022,5.39752,0.007,H,A,0.69,-0.37,0.745,,93.01,APH,-1.97933,0.221079,0.00306559,0.882423 beta-lactamase_0_V259Y,beta-lactamase_0_259,TEM-1,beta-lactamase_0,P62593,0.882428,NO,259,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.0500837,0.0070773,0.882428 beta-lactamase_I3R,beta-lactamase_3,TEM-1,beta-lactamase,P62593,0.882468,NO,3,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-2.143,-3.654,1.511,,,,,,,3.946,,93.01,PHP,-2.21633,0.221079,0.00349304,0.882468 beta-lactamase_0_G281R,beta-lactamase_0_281,TEM-1,beta-lactamase_0,P62593,0.882548,NO,281,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.0500837,0.0406482,0.882548 beta-lactamase_2500_F58Q,beta-lactamase_2500_58,TEM-1,beta-lactamase_2500,P62593,0.882591,NO,58,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-2.914,-2.803,-0.111,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.361275,0.00523369,0.882591 beta-lactamase_0_T139G,beta-lactamase_0_139,TEM-1,beta-lactamase_0,P62593,0.882594,NO,139,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.901,-3.413,1.512,,0.216,H,A,0.22,0.39,0.421,,77.62,PPH,-2.04667,0.0500837,0.00441837,0.882594 beta-lactamase_2500_P255Q,beta-lactamase_2500_255,TEM-1,beta-lactamase_2500,P62593,0.882609,NO,255,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.361275,0.00499612,0.882609 kka2_1:8_C192A,kka2_1:8_192,Kka2,kka2_1:8,P00552,0.882626,NO,192,C,A,CA,Special,Hydrophobic,5.07,6,0.93,195,121,89,-32,108.5,88.6,-19.9,-1.067,-2.954,1.887,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.100394,0.00485428,0.882626 kka2_1:8_C192A,kka2_1:8_192,Kka2,kka2_1:8,P00552,0.882626,NO,192,C,A,CA,Special,Hydrophobic,5.07,6,0.93,195,121,89,-32,108.5,88.6,-19.9,-1.067,-2.954,1.887,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.100394,0.00485428,0.882626 kka2_1:2_L193F,kka2_1:2_193,Kka2,kka2_1:2,P00552,0.882646,NO,193,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.983,-3.816,2.833,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.295029,0.00480179,0.882646 Pab1_K140Y,Pab1_140,Pab1,Pab1,P04147,0.88265,NO,140,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.083,-3.98,2.897,,0.345,H,A,,-0.73,,,,PBH,-1.20767,0.175299,0.000337366,0.88265 beta-lactamase_0_I285K,beta-lactamase_0_285,TEM-1,beta-lactamase_0,P62593,0.882672,NO,285,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.0500837,0.101555,0.882672 beta-lactamase_39_L191K,beta-lactamase_39_191,TEM-1,beta-lactamase_39,P62593,0.882689,NO,191,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.087,-3.741,2.654,,,H,A,0.55,0.09,1.372,,63.29,BHH,-1.445,0.0495842,0.00263549,0.882689 kka2_1:2_D208A,kka2_1:2_208,Kka2,kka2_1:2,P00552,0.882765,NO,208,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.708,-3.331,2.623,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.295029,0.00212588,0.882765 beta-lactamase_F228I,beta-lactamase_228,TEM-1,beta-lactamase,P62593,0.882793,NO,228,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-2.342,-3.049,0.707,5.33448,0.154,E,B,1.1,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.221079,0.0046669,0.882793 beta-lactamase_A211Y,beta-lactamase_211,TEM-1,beta-lactamase,P62593,0.882841,NO,211,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.896,-4.344,2.448,5.54662,0.369,T,A,0.52,-0.69,2.061,,77.62,AHA,-1.94633,0.221079,0.00648183,0.882841 beta-lactamase_M127H,beta-lactamase_127,TEM-1,beta-lactamase,P62593,0.882841,NO,127,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-2.251,-4.786,2.535,5.40552,0.312,S,A,1.07,0.32,1.671,,72.73,PHP,-1.40433,0.221079,0.00437927,0.882841 Pab1_M189S,Pab1_189,Pab1,Pab1,P04147,0.882864,NO,189,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.406,-3.203,1.797,,0.631,E,b,,2.81,,,,OHH,-1.18,0.175299,0.000278756,0.882864 beta-lactamase_156_T158I,beta-lactamase_156_158,TEM-1,beta-lactamase_156,P62593,0.882869,NO,158,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.116,-3.731,2.615,,0.036,,B,0.22,-0.85,3.771,,69.58,HPB,-1.269,0.111618,0.00341825,0.882869 beta-lactamase_2500_A84W,beta-lactamase_2500_84,TEM-1,beta-lactamase_2500,P62593,0.882874,NO,84,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.651,-5.52,3.869,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.361275,0.00503822,0.882874 beta-lactamase_0_S266R,beta-lactamase_0_266,TEM-1,beta-lactamase_0,P62593,0.882881,NO,266,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.0500837,0.0140785,0.882881 WW_domain_T196I,WW_domain_196,Yap65,WW_domain,P46937,0.882883,NO,196,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.782,-2.335,0.553,5.5744,,,,,,5.836,,70.04,PPP,-1.732,0.153962,0.00421377,0.882883 Pab1_G150A,Pab1_150,Pab1,Pab1,P04147,0.882897,NO,150,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.809,-2.67,1.861,,0.287,S,b,0.23,0.53,,,,HOA,-1.45233,0.175299,0.000323835,0.882897 beta-lactamase_2500_S57Y,beta-lactamase_2500_57,TEM-1,beta-lactamase_2500,P62593,0.882899,NO,57,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.918,-4.294,2.376,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.361275,0.00492804,0.882899 beta-lactamase_0_F64D,beta-lactamase_0_64,TEM-1,beta-lactamase_0,P62593,0.88291,NO,64,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-0.841,-3.919,3.078,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.0500837,0.000947691,0.88291 beta-lactamase_0_A133N,beta-lactamase_0_133,TEM-1,beta-lactamase_0,P62593,0.88292,NO,133,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.186,-3.758,2.572,,,H,A,0.46,-0.86,2.148,,67.83,HHP,-0.988333,0.0500837,0.00468022,0.88292 beta-lactamase_E119N,beta-lactamase_119,TEM-1,beta-lactamase,P62593,0.883062,NO,119,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.412,-3.591,2.179,5.33349,0.358,H,A,1.52,0.51,1.983,,63.99,BAH,-1.623,0.221079,0.00386966,0.883062 beta-lactamase_S51Y,beta-lactamase_51,TEM-1,beta-lactamase,P62593,0.883062,NO,51,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.526,-4.345,2.819,5.06164,0.496,T,A,0.25,0.26,1.699,,72.73,PPO,-1.88467,0.221079,0.00504821,0.883062 beta-lactamase_39_M184K,beta-lactamase_39_184,TEM-1,beta-lactamase_39,P62593,0.883088,NO,184,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.593,-3.659,2.066,,,H,A,0.55,-0.87,2.893,,62.94,HHH,-1.41,0.0495842,0.00356019,0.883088 beta-lactamase_2500_I54E,beta-lactamase_2500_54,TEM-1,beta-lactamase_2500,P62593,0.883089,NO,54,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-2.838,-2.58,-0.258,,0.669,E,B,0.48,-0.14,3.946,,73.78,BHH,-2.337,0.361275,0.00403589,0.883089 beta-lactamase_0_L205V,beta-lactamase_0_205,TEM-1,beta-lactamase_0,P62593,0.883094,NO,205,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.922,-2.938,2.016,,,H,A,0.55,-0.46,1.065,,42.31,PHH,-1.57767,0.0500837,0.00255802,0.883094 Pab1_E181R,Pab1_181,Pab1,Pab1,P04147,0.883094,NO,181,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.767,-3.62,1.853,,,,,,,1.395,,73.83,BAH,-1.575,0.175299,0.00107557,0.883094 beta-lactamase_39_A235W,beta-lactamase_39_235,TEM-1,beta-lactamase_39,P62593,0.883096,NO,235,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.266,-5.379,4.113,,0.32,E,B,0.46,-0.86,1.344,,50,OHO,-0.89,0.0495842,0.00493474,0.883096 kka2_1:4_A191P,kka2_1:4_191,Kka2,kka2_1:4,P00552,0.88317,NO,191,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.831,-2.353,1.522,,,.,b,0.46,-0.94,2.046,,50,AHO,-0.868667,0.168804,0.00338807,0.88317 beta-lactamase_0_T193M,beta-lactamase_0_193,TEM-1,beta-lactamase_0,P62593,0.883184,NO,193,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.914,-4.362,2.448,,0.439,H,a,0.22,0.33,11.546,11.546,63.99,HPO,-1.52133,0.0500837,0.00482669,0.883184 beta-lactamase_156_V117S,beta-lactamase_156_117,TEM-1,beta-lactamase_156,P62593,0.883194,NO,117,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.53,-3.729,2.199,,,H,A,0.44,-0.34,1.182,,65.03,PHB,-1.741,0.111618,0.00467906,0.883194 beta-lactamase_R162Q,beta-lactamase_162,TEM-1,beta-lactamase,P62593,0.883233,NO,162,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.016,-3.59,2.574,5.34456,0.124,S,B,0.68,-0.37,31.656,31.656,64.69,ABH,-1.25,0.221079,0.000561334,0.883233 beta-lactamase_39_D155A,beta-lactamase_39_155,TEM-1,beta-lactamase_39,P62593,0.883277,NO,155,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.889,-3.327,2.438,,0.049,,B,0.75,-0.9,3.208,,64.69,OAB,-1.62267,0.0495842,0.00135315,0.883277 beta-lactamase_C121M,beta-lactamase_121,TEM-1,beta-lactamase,P62593,0.883292,NO,121,C,M,CM,Special,Hydrophobic,5.07,5.74,0.67,196,121,149,28,108.5,162.9,54.4,-0.953,-4.506,3.553,5.12205,,H,A,2.8,-0.81,7.644,,63.29,HOP,-1.46767,0.221079,0.000744322,0.883292 beta-lactamase_0_L199M,beta-lactamase_0_199,TEM-1,beta-lactamase_0,P62593,0.883294,NO,199,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-2.942,-4.728,1.786,,0.832,H,A,0.55,0.42,10.85,10.85,77.62,PHH,-2.32933,0.0500837,0.0048649,0.883294 beta-lactamase_R63V,beta-lactamase_63,TEM-1,beta-lactamase,P62593,0.883305,NO,63,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-0.943,-3.626,2.683,5.49979,0.218,,B,0.45,-0.31,0.677,,44.06,ABH,-0.992333,0.221079,0.00126938,0.883305 beta-lactamase_G43A,beta-lactamase_43,TEM-1,beta-lactamase,P62593,0.883339,NO,43,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.62,-2.853,2.233,5.28886,,E,B,0.77,-0.78,,,,HOH,-1.577,0.221079,0.00120151,0.883339 kka2_1:4_P179A,kka2_1:4_179,Kka2,kka2_1:4,P00552,0.883341,NO,179,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.974,-2.519,1.545,,0.113,,B,0.52,0.69,10.913,10.913,56.06,HOA,-2.19867,0.168804,0.00298346,0.883341 beta-lactamase_39_N274F,beta-lactamase_39_274,TEM-1,beta-lactamase_39,P62593,0.883369,NO,274,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.0495842,0.0110418,0.883369 beta-lactamase_156_A34E,beta-lactamase_156_34,TEM-1,beta-lactamase_156,P62593,0.88339,NO,34,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.059,-3.743,1.684,,,H,A,0.46,-0.54,3.614,,73.78,AHA,-1.74967,0.111618,0.00407913,0.88339 kka2_1:8_N200W,kka2_1:8_200,Kka2,kka2_1:8,P00552,0.883459,NO,200,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-2.446,-5.597,3.151,,0.756,T,L,0.43,-0.08,2.528,,64.39,APO,-2.08,0.100394,0.00838549,0.883459 kka2_1:8_N200W,kka2_1:8_200,Kka2,kka2_1:8,P00552,0.883459,NO,200,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-2.446,-5.597,3.151,,0.756,T,L,0.43,-0.08,2.528,,64.39,APO,-2.08,0.100394,0.00838549,0.883459 beta-lactamase_0_L89A,beta-lactamase_0_89,TEM-1,beta-lactamase_0,P62593,0.883466,NO,89,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.096,-2.465,1.369,,0.168,T,A,0.55,0.63,2.373,,64.34,PHO,-1.75767,0.0500837,0.00207068,0.883466 beta-lactamase_F58I,beta-lactamase_58,TEM-1,beta-lactamase,P62593,0.883482,NO,58,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-2.914,-3.971,1.057,5.55634,0.266,E,B,1.33,-0.07,2.467,,77.62,PHB,-2.059,0.221079,0.00523369,0.883482 beta-lactamase_G90P,beta-lactamase_90,TEM-1,beta-lactamase,P62593,0.883482,NO,90,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-2.091,-3.952,1.861,5.51991,0.598,T,A,0.23,0.32,1.791,,77.62,HOB,-1.52633,0.221079,0.00490273,0.883482 beta-lactamase_0_K53R,beta-lactamase_0_53,TEM-1,beta-lactamase_0,P62593,0.883504,NO,53,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-2.313,-2.027,-0.286,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.0500837,0.00383383,0.883504 kka2_1:8_D52Y,kka2_1:8_52,Kka2,kka2_1:8,P00552,0.883541,NO,52,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.271,-4.235,1.964,,0.22,E,B,0.75,0.8,5.447,,71.59,PAH,-2.38367,0.100394,0.00175694,0.883541 kka2_1:8_D52Y,kka2_1:8_52,Kka2,kka2_1:8,P00552,0.883541,NO,52,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.271,-4.235,1.964,,0.22,E,B,0.75,0.8,5.447,,71.59,PAH,-2.38367,0.100394,0.00175694,0.883541 kka2_1:4_D134T,kka2_1:4_134,Kka2,kka2_1:4,P00552,0.883552,NO,134,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.969,-3.471,2.502,,0.421,B,B,0.75,0.31,0.733,,49.62,HAB,-1.057,0.168804,0.00270812,0.883552 beta-lactamase_D174E,beta-lactamase_174,TEM-1,beta-lactamase,P62593,0.883573,NO,174,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.738,-2.765,2.027,5.44133,0.238,,B,1.22,-0.1,,,,PAA,-1.91233,0.221079,0.00125633,0.883573 Pab1_E181P,Pab1_181,Pab1,Pab1,P04147,0.883587,NO,181,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.767,-3.6,1.833,,,,,,,1.395,,73.83,BAH,-1.575,0.175299,0.00107557,0.883587 beta-lactamase_0_N152E,beta-lactamase_0_152,TEM-1,beta-lactamase_0,P62593,0.883631,NO,152,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-2.757,-2.679,-0.078,,0.863,H,A,0.61,0.92,2.151,,77.62,BPH,-2.97,0.0500837,0.00471429,0.883631 beta-lactamase_0_L199S,beta-lactamase_0_199,TEM-1,beta-lactamase_0,P62593,0.883634,NO,199,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-2.942,-2.568,-0.374,,0.832,H,A,0.55,0.42,10.85,10.85,77.62,PHH,-2.32933,0.0500837,0.0048649,0.883634 beta-lactamase_39_D212Y,beta-lactamase_39_212,TEM-1,beta-lactamase_39,P62593,0.883668,NO,212,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.624,-4.398,2.774,,0.037,,b,0.75,-0.58,10.748,10.748,74.48,HAB,-1.77667,0.0495842,0.00644302,0.883668 PSD95pdz3_L360D,PSD95pdz3_360,PSD95pdz3,PSD95pdz3,P31016,0.883686,NO,360,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.431,-3.825,2.394,5.09284,,,,,14.2425,1.419,,86.88,HHP,-1.52667,0.0758425,0.000770471,0.883686 kka2_1:2_A166W,kka2_1:2_166,Kka2,kka2_1:2,P00552,0.883698,NO,166,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.407,-5.55,3.143,,0.534,.,B,0.46,1.03,23.175,23.175,71.59,HHO,-2.421,0.295029,0.00799912,0.883698 kka2_1:1_M178L,kka2_1:1_178,Kka2,kka2_1:1,P00552,0.883701,NO,178,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-3.206,-2.71,-0.496,,0.554,.,b,0.55,0.68,3.152,,71.59,BHO,-2.154,0.520039,0.00717253,0.883701 kka2_1:1_K175C,kka2_1:1_175,Kka2,kka2_1:1,P00552,0.883708,NO,175,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-2.897,-2.882,-0.015,,0.579,H,A,1.3,0.51,9.33,9.33,71.59,HBH,-1.82333,0.520039,0.00693093,0.883708 beta-lactamase_0_G249V,beta-lactamase_0_249,TEM-1,beta-lactamase_0,P62593,0.88376,NO,249,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.0500837,0.00220169,0.88376 beta-lactamase_0_G243V,beta-lactamase_0_243,TEM-1,beta-lactamase_0,P62593,0.883772,NO,243,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.0500837,0.00464034,0.883772 beta-lactamase_A40N,beta-lactamase_40,TEM-1,beta-lactamase,P62593,0.88378,NO,40,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.402,-3.756,2.354,4.9697,0.155,S,B,1.2,0.21,1.714,,73.78,OHB,-1.40267,0.221079,0.00490026,0.88378 beta-lactamase_G194W,beta-lactamase_194,TEM-1,beta-lactamase,P62593,0.88378,NO,194,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.396,-5.42,4.024,5.46622,0.276,S,b,0.77,0.36,3.593,,67.83,POA,-1.832,0.221079,0.00392163,0.88378 beta-lactamase_M153Y,beta-lactamase_153,TEM-1,beta-lactamase,P62593,0.88378,NO,153,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-3.193,-4.187,0.994,5.46509,0.14,T,A,1.07,-0.11,2.061,,77.62,PHO,-2.25767,0.221079,0.00509109,0.88378 beta-lactamase_Q4D,beta-lactamase_4,TEM-1,beta-lactamase,P62593,0.88378,NO,4,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,,-3.401,0.837,,,,,,,,,,HPB,,0.221079,0.00316562,0.88378 beta-lactamase_R202H,beta-lactamase_202,TEM-1,beta-lactamase,P62593,0.88378,NO,202,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.292,-4.365,3.073,5.16273,0.188,H,A,0.68,0.62,1.918,,77.62,PBP,-1.54767,0.221079,0.00321899,0.88378 beta-lactamase_V101F,beta-lactamase_101,TEM-1,beta-lactamase,P62593,0.88378,NO,101,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.295,-3.936,2.641,5.49045,0.342,,B,0.96,0,1.675,,73.08,HHA,-1.54367,0.221079,0.00374492,0.88378 beta-lactamase_V8W,beta-lactamase_8,TEM-1,beta-lactamase,P62593,0.88378,NO,8,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-2.358,-5.121,2.763,,,,,,,0.575,,77.62,BHH,-2.06267,0.221079,0.00226401,0.88378 Pab1_E174P,Pab1_174,Pab1,Pab1,P04147,0.883817,NO,174,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.422,-3.637,2.215,,0.578,S,A,,0.38,,,,HAA,-1.65133,0.175299,0.00077863,0.883817 beta-lactamase_0_K190Q,beta-lactamase_0_190,TEM-1,beta-lactamase_0,P62593,0.88384,NO,190,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.994,-2.883,0.889,,0.371,H,A,2.34,0.16,16.606,16.606,77.62,BBH,-1.64167,0.0500837,0.00574527,0.88384 beta-lactamase_0_D36L,beta-lactamase_0_36,TEM-1,beta-lactamase_0,P62593,0.883845,NO,36,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.732,-3.628,0.896,,0.555,H,A,0.75,1.17,13.689,13.689,77.62,AAP,-1.91167,0.0500837,0.00476483,0.883845 kka2_1:4_D156Y,kka2_1:4_156,Kka2,kka2_1:4,P00552,0.883847,NO,156,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.696,-4.451,2.755,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.168804,0.00926998,0.883847 beta-lactamase_0_M184P,beta-lactamase_0_184,TEM-1,beta-lactamase_0,P62593,0.883851,NO,184,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.593,-4.009,2.416,,,H,A,0.55,-0.87,13.292,13.292,62.94,HHH,-1.41,0.0500837,0.00356019,0.883851 beta-lactamase_0_S104Q,beta-lactamase_0_104,TEM-1,beta-lactamase_0,P62593,0.883869,NO,104,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.015,-3.815,2.8,,0.04,,b,0.27,0.57,1.148,,63.29,HPO,-1.05267,0.0500837,0.00218083,0.883869 beta-lactamase_0_K32S,beta-lactamase_0_32,TEM-1,beta-lactamase_0,P62593,0.883888,NO,32,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.984,-3.371,1.387,,0.563,H,A,2.34,0.34,0.418,,73.08,HBA,-2.04233,0.0500837,0.00401283,0.883888 kka2_1:4_G210Q,kka2_1:4_210,Kka2,kka2_1:4,P00552,0.883918,NO,210,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.095,-4.139,3.044,,0.103,T,A,0.29,-0.62,0.271,,50,OOB,-0.966667,0.168804,0.00598378,0.883918 beta-lactamase_0_G114V,beta-lactamase_0_114,TEM-1,beta-lactamase_0,P62593,0.883921,NO,114,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.094,-3.65,2.556,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.0500837,0.00224919,0.883921 beta-lactamase_R238I,beta-lactamase_238,TEM-1,beta-lactamase,P62593,0.883974,NO,238,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.002,-4.001,1.999,5.87663,0.564,T,L,0.45,1.09,4.195,,72.73,ABO,-1.62633,0.221079,0.00743256,0.883974 beta-lactamase_0_P217C,beta-lactamase_0_217,TEM-1,beta-lactamase_0,P62593,0.884048,NO,217,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-2.062,-5.064,3.002,,0.496,I,A,0.52,-0.33,1.087,,74.48,OOH,-1.64333,0.0500837,0.00463211,0.884048 beta-lactamase_39_T107W,beta-lactamase_39_107,TEM-1,beta-lactamase_39,P62593,0.884078,NO,107,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.117,-5.223,4.106,,,G,A,0.22,-0.06,2.686,,67.83,HPA,-1.265,0.0495842,0.00239347,0.884078 beta-lactamase_G263A,beta-lactamase_263,TEM-1,beta-lactamase,P62593,0.884094,NO,263,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-2.031,-2.716,0.685,5.09799,0.517,S,l,0.77,0.31,16.425,16.425,77.62,POP,-1.78267,0.221079,0.0110582,0.884094 beta-lactamase_625_L49G,beta-lactamase_625_49,TEM-1,beta-lactamase_625,P62593,0.884098,NO,49,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.897,-3.581,1.684,,0.131,T,A,0.55,0.04,3.112,,64.69,AHP,-1.99233,0.213352,0.00401477,0.884098 beta-lactamase_0_R162V,beta-lactamase_0_162,TEM-1,beta-lactamase_0,P62593,0.884099,NO,162,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.016,-3.642,2.626,,0.124,S,B,1.2,-0.37,1.026,,64.69,ABH,-1.25,0.0500837,0.000561334,0.884099 kka2_1:4_I246H,kka2_1:4_246,Kka2,kka2_1:4,P00552,0.884105,NO,246,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-2.008,-5.017,3.009,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.168804,0.0139479,0.884105 PSD95pdz3_G351V,PSD95pdz3_351,PSD95pdz3,PSD95pdz3,P31016,0.884135,NO,351,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.008,-3.435,2.427,5.44798,,,,,20.7625,,,,POA,-1.37133,0.0758425,0.000691282,0.884135 E1_Ubiquitin_K48P,E1_Ubiquitin_48,Uba1,E1_Ubiquitin,P0CG63,0.884173,NO,48,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.219,-3.525,2.306,,0.132,E,B,,-0.28,,,,OBO,-1.109,0.18783,0.00100363,0.884173 beta-lactamase_L74V,beta-lactamase_74,TEM-1,beta-lactamase,P62593,0.884211,NO,74,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.296,-2.972,1.676,5.50288,,H,A,1.75,-0.91,1.581,,50,HHO,-1.34933,0.221079,0.00493255,0.884211 beta-lactamase_0_F149K,beta-lactamase_0_149,TEM-1,beta-lactamase_0,P62593,0.884215,NO,149,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.299,-3.859,2.56,,0.195,H,A,0.58,0.11,3.518,,63.99,HHH,-1.46067,0.0500837,0.00418462,0.884215 kka2_1:8_A229V,kka2_1:8_229,Kka2,kka2_1:8,P00552,0.884242,NO,229,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.739,-2.471,0.732,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.100394,0.00942138,0.884242 kka2_1:8_A229V,kka2_1:8_229,Kka2,kka2_1:8,P00552,0.884242,NO,229,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.739,-2.471,0.732,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.100394,0.00942138,0.884242 kka2_1:8_D159Q,kka2_1:8_159,Kka2,kka2_1:8,P00552,0.884266,NO,159,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.82,-3.79,2.97,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.100394,0.0030485,0.884266 kka2_1:8_D159Q,kka2_1:8_159,Kka2,kka2_1:8,P00552,0.884266,NO,159,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.82,-3.79,2.97,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.100394,0.0030485,0.884266 PSD95pdz3_I314P,PSD95pdz3_314,PSD95pdz3,PSD95pdz3,P31016,0.884266,NO,314,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.628,-3.785,2.157,5.39919,,,,,15.7775,0.397,,81.35,BHH,-1.61167,0.0758425,0.0012606,0.884266 beta-lactamase_R162T,beta-lactamase_162,TEM-1,beta-lactamase,P62593,0.884311,NO,162,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.016,-3.471,2.455,5.34456,0.124,S,B,0.68,-0.37,31.656,31.656,64.69,ABH,-1.25,0.221079,0.000561334,0.884311 kka2_1:2_A35E,kka2_1:2_35,Kka2,kka2_1:2,P00552,0.884332,NO,35,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.127,-2.492,0.365,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.295029,0.00630016,0.884332 kka2_1:2_A87L,kka2_1:2_87,Kka2,kka2_1:2,P00552,0.884361,NO,87,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.917,-3.08,1.163,,1.039,S,L,0.46,1.57,22.675,22.675,65.53,AHO,-1.822,0.295029,0.00791281,0.884361 beta-lactamase_A15Q,beta-lactamase_15,TEM-1,beta-lactamase,P62593,0.884381,NO,15,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.654,-3.891,2.237,,,,,,,31.998,31.998,93.01,HHH,-2.10833,0.221079,0.00248966,0.884381 beta-lactamase_0_R162D,beta-lactamase_0_162,TEM-1,beta-lactamase_0,P62593,0.884415,NO,162,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.016,-3.754,2.738,,0.124,S,B,1.2,-0.37,1.026,,64.69,ABH,-1.25,0.0500837,0.000561334,0.884415 beta-lactamase_L10P,beta-lactamase_10,TEM-1,beta-lactamase,P62593,0.884423,NO,10,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.623,-4.021,2.398,,,,,,,2.467,,65.38,HHH,-1.83833,0.221079,0.00296968,0.884423 WW_domain_K181A,WW_domain_181,Yap65,WW_domain,P46937,0.884428,NO,181,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.35,-2.977,1.627,5.0864,,,,,,0.176,,15.87,HBP,-1.247,0.153962,0.0033022,0.884428 beta-lactamase_M268S,beta-lactamase_268,TEM-1,beta-lactamase,P62593,0.884451,NO,268,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-2.023,-3.599,1.576,5.4797,0.471,H,A,0.09,0.3,1.071,,65.73,PHA,-2.16233,0.221079,0.0102525,0.884451 kka2_1:4_G164P,kka2_1:4_164,Kka2,kka2_1:4,P00552,0.884464,NO,164,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.869,-3.944,3.075,,0.862,T,l,0.75,1.45,1.539,,64.39,POH,-1.828,0.168804,0.00442091,0.884464 kka2_1:4_L47P,kka2_1:4_47,Kka2,kka2_1:4,P00552,0.884469,NO,47,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.265,-4.146,2.881,,0.139,E,B,0.55,-0.86,2.369,,63.26,HHH,-1.77933,0.168804,0.00509386,0.884469 kka2_1:8_D101T,kka2_1:8_101,Kka2,kka2_1:8,P00552,0.884499,NO,101,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.028,-3.464,2.436,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.100394,0.00423361,0.884499 kka2_1:8_D101T,kka2_1:8_101,Kka2,kka2_1:8,P00552,0.884499,NO,101,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.028,-3.464,2.436,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.100394,0.00423361,0.884499 beta-lactamase_Q4G,beta-lactamase_4,TEM-1,beta-lactamase,P62593,0.884516,NO,4,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,,-3.319,0.755,,,,,,,,,,HPB,,0.221079,0.00316562,0.884516 kka2_1:2_A255M,kka2_1:2_255,Kka2,kka2_1:2,P00552,0.884547,NO,255,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.715,-4.815,3.1,,0.466,H,A,0.46,-0.52,5.144,,65.53,HHH,-1.71267,0.295029,0.0126809,0.884547 beta-lactamase_A266F,beta-lactamase_266,TEM-1,beta-lactamase,P62593,0.884595,NO,266,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.369,-4.191,2.822,5.02057,0.175,S,B,0.52,0.07,1.832,,64.34,PHP,-2.08567,0.221079,0.0140785,0.884595 beta-lactamase_E61C,beta-lactamase_61,TEM-1,beta-lactamase,P62593,0.884595,NO,61,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.115,-5.186,3.071,6.29701,0.775,T,a,0.52,1.29,1.975,,77.62,OAA,-1.92567,0.221079,0.00440955,0.884595 beta-lactamase_P249E,beta-lactamase_249,TEM-1,beta-lactamase,P62593,0.884595,NO,249,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.312,-3.541,2.229,5.10655,0.256,S,B,0.99,0.04,0.479,,72.73,OOA,-1.81367,0.221079,0.00220169,0.884595 beta-lactamase_625_I285K,beta-lactamase_625_285,TEM-1,beta-lactamase_625,P62593,0.884602,NO,285,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.213352,0.101555,0.884602 beta-lactamase_0_L28C,beta-lactamase_0_28,TEM-1,beta-lactamase_0,P62593,0.884605,NO,28,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.579,-4.763,3.184,,0.277,H,A,0.55,-0.16,9.35,9.35,93.01,PHH,-2.11333,0.0500837,0.00359321,0.884605 kka2_1:4_L165G,kka2_1:4_165,Kka2,kka2_1:4,P00552,0.884616,NO,165,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-2.453,-3.006,0.553,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.168804,0.00801161,0.884616 kka2_1:8_L19N,kka2_1:8_19,Kka2,kka2_1:8,P00552,0.884616,NO,19,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.254,-4.186,2.932,,0.08,T,A,1.59,-0.26,2.044,,65.53,BHH,-2.221,0.100394,0.00620703,0.884616 kka2_1:8_L19N,kka2_1:8_19,Kka2,kka2_1:8,P00552,0.884616,NO,19,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.254,-4.186,2.932,,0.08,T,A,1.59,-0.26,2.044,,65.53,BHH,-2.221,0.100394,0.00620703,0.884616 PSD95pdz3_G345R,PSD95pdz3_345,PSD95pdz3,PSD95pdz3,P31016,0.884646,NO,345,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.008,-3.615,2.607,4.32868,,,,,13.165,,,,OOO,-1.084,0.0758425,0.000771806,0.884646 beta-lactamase_0_T193P,beta-lactamase_0_193,TEM-1,beta-lactamase_0,P62593,0.884705,NO,193,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.914,-4.072,2.158,,0.439,H,a,0.22,0.33,11.546,11.546,63.99,HPO,-1.52133,0.0500837,0.00482669,0.884705 beta-lactamase_0_L218R,beta-lactamase_0_218,TEM-1,beta-lactamase_0,P62593,0.884743,NO,218,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.391,-2.276,0.885,,,I,b,0.55,-0.53,28.707,28.707,74.48,OHH,-1.58867,0.0500837,0.00618274,0.884743 kka2_1:2_G21Q,kka2_1:2_21,Kka2,kka2_1:2,P00552,0.884752,NO,21,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.368,-2.867,1.499,,0.586,T,l,0.29,-0.75,2.026,,71.59,HOH,-2.10167,0.295029,0.00709648,0.884752 PSD95pdz3_K380A,PSD95pdz3_380,PSD95pdz3,PSD95pdz3,P31016,0.884752,NO,380,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.416,-2.759,1.343,5.87979,,,,,19.6722,,,,HBP,-1.391,0.0758425,0.000281399,0.884752 beta-lactamase_0_L191R,beta-lactamase_0_191,TEM-1,beta-lactamase_0,P62593,0.884878,NO,191,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.087,-4.02,2.933,,,H,A,0.55,0.09,12.255,12.255,63.29,BHH,-1.445,0.0500837,0.00263549,0.884878 gb1_T270V,gb1_270,gb1,gb1,P06654,0.884885,NO,270,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-3.15,-3.321,0.171,,,,,,,1.326,,45.54,HPH,-1.843,0.177985,0.00223707,0.884885 beta-lactamase_0_F70G,beta-lactamase_0_70,TEM-1,beta-lactamase_0,P62593,0.88493,NO,70,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.169,-3.574,2.405,,,H,A,0.58,-1.34,2.153,,63.99,PHB,-0.980667,0.0500837,0.00193499,0.88493 kka2_1:8_P167E,kka2_1:8_167,Kka2,kka2_1:8,P00552,0.884943,NO,167,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-2.403,-3.663,1.26,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.100394,0.00543203,0.884943 kka2_1:8_P167E,kka2_1:8_167,Kka2,kka2_1:8,P00552,0.884943,NO,167,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-2.403,-3.663,1.26,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.100394,0.00543203,0.884943 beta-lactamase_2500_A77R,beta-lactamase_2500_77,TEM-1,beta-lactamase_2500,P62593,0.88499,NO,77,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.234,-3.891,2.657,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.361275,0.00282362,0.88499 beta-lactamase_0_T178Y,beta-lactamase_0_178,TEM-1,beta-lactamase_0,P62593,0.884992,NO,178,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-0.791,-4.162,3.371,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.0500837,0.000684366,0.884992 beta-lactamase_0_E166P,beta-lactamase_0_166,TEM-1,beta-lactamase_0,P62593,0.885009,NO,166,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.756,-3.897,2.141,,0.508,G,A,1.04,1.05,17.227,17.227,73.08,OAH,-1.42233,0.0500837,0.00512989,0.885009 beta-lactamase_0_L136S,beta-lactamase_0_136,TEM-1,beta-lactamase_0,P62593,0.885009,NO,136,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.232,-3.705,2.473,,,H,A,0.55,-0.34,0.648,,48.95,HHH,-1.088,0.0500837,0.00442304,0.885009 beta-lactamase_E102K,beta-lactamase_102,TEM-1,beta-lactamase,P62593,0.885013,NO,102,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.118,-2.64,0.522,6.36157,0.722,S,B,1.5,1.82,1.336,,73.08,HAH,-1.581,0.221079,0.00486633,0.885013 beta-lactamase_G194Y,beta-lactamase_194,TEM-1,beta-lactamase,P62593,0.885044,NO,194,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.396,-4.427,3.031,5.46622,0.276,S,b,0.77,0.36,3.593,,67.83,POA,-1.832,0.221079,0.00392163,0.885044 kka2_1:1_V83K,kka2_1:1_83,Kka2,kka2_1:1,P00552,0.885059,NO,83,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-2.567,-3.653,1.086,,0.358,E,B,0.44,0.53,5.931,,71.59,AHH,-2.264,0.520039,0.00650486,0.885059 beta-lactamase_0_K71G,beta-lactamase_0_71,TEM-1,beta-lactamase_0,P62593,0.885087,NO,71,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-0.8,-3.358,2.558,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.0500837,0.00103192,0.885087 kka2_1:4_V80Q,kka2_1:4_80,Kka2,kka2_1:4,P00552,0.885092,NO,80,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.144,-4.244,3.1,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.168804,0.00488211,0.885092 kka2_1:1_P194R,kka2_1:1_194,Kka2,kka2_1:1,P00552,0.885126,NO,194,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.846,-3.983,3.137,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.520039,0.00314194,0.885126 beta-lactamase_E62S,beta-lactamase_62,TEM-1,beta-lactamase,P62593,0.885138,NO,62,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.193,-3.245,2.052,5.93066,0.342,S,B,1.52,-0.3,3.139,,73.08,AAB,-1.417,0.221079,0.00264802,0.885138 beta-lactamase_0_K30Y,beta-lactamase_0_30,TEM-1,beta-lactamase_0,P62593,0.885172,NO,30,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-2.307,-4.255,1.948,,0.142,H,A,2.34,-0.65,1.491,,93.01,HBH,-2.32833,0.0500837,0.00448593,0.885172 beta-lactamase_0_R257L,beta-lactamase_0_257,TEM-1,beta-lactamase_0,P62593,0.885197,NO,257,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.0500837,0.00756629,0.885197 kka2_1:1_A248K,kka2_1:1_248,Kka2,kka2_1:1,P00552,0.88521,NO,248,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.124,-2.875,0.751,,0.825,S,b,0.46,0.46,24.72,24.72,92.05,HHO,-2.15,0.520039,0.0125484,0.88521 kka2_1:2_L92V,kka2_1:2_92,Kka2,kka2_1:2,P00552,0.885229,NO,92,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.893,-2.208,1.315,,0.007,E,B,1.59,-0.19,1.447,,63.26,HHH,-0.962,0.295029,0.00307177,0.885229 beta-lactamase_39_M66E,beta-lactamase_39_66,TEM-1,beta-lactamase_39,P62593,0.885245,NO,66,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.362,-3.832,2.47,,0.013,,A,0.55,-0.7,1.319,,73.08,OHH,-1.49567,0.0495842,0.00412876,0.885245 beta-lactamase_0_R63Q,beta-lactamase_0_63,TEM-1,beta-lactamase_0,P62593,0.885273,NO,63,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-0.943,-3.532,2.589,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.0500837,0.00126938,0.885273 kka2_1:4_G55K,kka2_1:4_55,Kka2,kka2_1:4,P00552,0.885273,NO,55,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.625,-3.726,2.101,,0.517,S,b,0.75,1.19,15.753,15.753,63.64,POH,-2.05967,0.168804,0.00667877,0.885273 beta-lactamase_K213G,beta-lactamase_213,TEM-1,beta-lactamase,P62593,0.885281,NO,213,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.81,-2.317,0.507,5.63167,0.67,,A,1.59,0.29,3.924,,67.83,ABH,-1.57767,0.221079,0.00610411,0.885281 kka2_1:1_G6Q,kka2_1:1_6,Kka2,kka2_1:1,P00552,0.885289,NO,6,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.685,-3.809,2.124,,,,,,,1.292,,71.59,AOH,-1.639,0.520039,0.00204693,0.885289 beta-lactamase_P249T,beta-lactamase_249,TEM-1,beta-lactamase,P62593,0.885314,NO,249,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.312,-2.762,1.45,5.10655,0.256,S,B,0.99,0.04,0.479,,72.73,OOA,-1.81367,0.221079,0.00220169,0.885314 kka2_1:2_M116C,kka2_1:2_116,Kka2,kka2_1:2,P00552,0.885344,NO,116,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-2.482,-3.43,0.948,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.295029,0.00745147,0.885344 beta-lactamase_0_E175Q,beta-lactamase_0_175,TEM-1,beta-lactamase_0,P62593,0.88537,NO,175,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.336,-3.092,0.756,,0.551,,A,1.04,1.05,2.334,,77.62,AAB,-1.31233,0.0500837,0.00482205,0.88537 beta-lactamase_2500_E26P,beta-lactamase_2500_26,TEM-1,beta-lactamase_2500,P62593,0.885397,NO,26,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.454,-2.862,0.408,,0.54,H,A,1.04,0.98,0.49,,93.01,OAP,-1.96167,0.361275,0.00297948,0.885397 PSD95pdz3_A376G,PSD95pdz3_376,PSD95pdz3,PSD95pdz3,P31016,0.885406,NO,376,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.307,-2.59,1.283,4.72134,,,,,17.108,,,,HHH,-1.49567,0.0758425,0.000341232,0.885406 kka2_1:2_K175G,kka2_1:2_175,Kka2,kka2_1:2,P00552,0.88541,NO,175,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-2.897,-3.762,0.865,,0.579,H,A,1.3,0.51,15.629,15.629,71.59,HBH,-1.82333,0.295029,0.00693093,0.88541 Pab1_D138T,Pab1_138,Pab1,Pab1,P04147,0.885497,NO,138,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.128,-3.292,2.164,,0.427,,B,,-0.03,,,,HAP,-1.13967,0.175299,0.000567877,0.885497 beta-lactamase_E277C,beta-lactamase_277,TEM-1,beta-lactamase,P62593,0.885525,NO,277,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.869,-5.159,3.29,5.51786,0.545,H,A,0.52,-0.01,2.022,,77.62,HAH,-1.45367,0.221079,0.0169305,0.885525 beta-lactamase_V101Y,beta-lactamase_101,TEM-1,beta-lactamase,P62593,0.885525,NO,101,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.295,-4.116,2.821,5.49045,0.342,,B,0.96,0,1.675,,73.08,HHA,-1.54367,0.221079,0.00374492,0.885525 beta-lactamase_156_N274R,beta-lactamase_156_274,TEM-1,beta-lactamase_156,P62593,0.885579,NO,274,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.111618,0.0110418,0.885579 Pab1_A179V,Pab1_179,Pab1,Pab1,P04147,0.885618,NO,179,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.013,-2.896,1.883,,0.078,H,A,0.61,0.5,,,,HHB,-1.51233,0.175299,0.000291703,0.885618 beta-lactamase_0_D174P,beta-lactamase_0_174,TEM-1,beta-lactamase_0,P62593,0.885662,NO,174,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.738,-3.655,2.917,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.0500837,0.00125633,0.885662 beta-lactamase_N168A,beta-lactamase_168,TEM-1,beta-lactamase,P62593,0.885681,NO,168,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-1.029,-3.17,2.141,5.42128,0.113,G,A,0.09,-0.4,1.211,,44.41,HPA,-1.13233,0.221079,0.00288667,0.885681 beta-lactamase_625_A215H,beta-lactamase_625_215,TEM-1,beta-lactamase_625,P62593,0.885702,NO,215,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.503,-4.741,3.238,,,,a,0.46,-0.93,3.583,,74.48,HHO,-1.42633,0.213352,0.00544007,0.885702 beta-lactamase_L150Y,beta-lactamase_150,TEM-1,beta-lactamase,P62593,0.885709,NO,150,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.326,-4.133,2.807,5.15566,,H,A,1.75,-0.2,1.615,,62.94,HHB,-1.86167,0.221079,0.00463171,0.885709 beta-lactamase_2500_R59K,beta-lactamase_2500_59,TEM-1,beta-lactamase_2500,P62593,0.885712,NO,59,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.345,-2.351,1.006,,0.329,S,L,1.2,-0.09,3.719,,73.08,HBO,-2.24267,0.361275,0.00318082,0.885712 PSD95pdz3_I377W,PSD95pdz3_377,PSD95pdz3,PSD95pdz3,P31016,0.885792,NO,377,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.873,-5.156,3.283,4.9532,,,,,19.185,2.364,,87.71,HHH,-1.49567,0.0758425,0.000795475,0.885792 kka2_1:4_P194T,kka2_1:4_194,Kka2,kka2_1:4,P00552,0.88582,NO,194,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.846,-3.444,2.598,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.168804,0.00314194,0.88582 beta-lactamase_0_Q204E,beta-lactamase_0_204,TEM-1,beta-lactamase_0,P62593,0.885823,NO,204,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-1.382,-3.106,1.724,,0.204,H,A,0.64,0.09,2.646,,66.08,PPH,-1.49067,0.0500837,0.00364106,0.885823 beta-lactamase_0_L135M,beta-lactamase_0_135,TEM-1,beta-lactamase_0,P62593,0.885853,NO,135,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.002,-2.838,1.836,,0.117,H,A,0.55,-0.58,0.705,,43.71,PHH,-1.03767,0.0500837,0.00244423,0.885853 beta-lactamase_0_G43P,beta-lactamase_0_43,TEM-1,beta-lactamase_0,P62593,0.885874,NO,43,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.62,-3.88,3.26,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.0500837,0.00120151,0.885874 kka2_1:8_E161K,kka2_1:8_161,Kka2,kka2_1:8,P00552,0.885875,NO,161,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.581,-3.478,1.897,,0.829,G,A,1.04,2.24,11.923,11.923,92.05,AAB,-1.861,0.100394,0.00760103,0.885875 kka2_1:8_E161K,kka2_1:8_161,Kka2,kka2_1:8,P00552,0.885875,NO,161,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.581,-3.478,1.897,,0.829,G,A,1.04,2.24,11.923,11.923,92.05,AAB,-1.861,0.100394,0.00760103,0.885875 beta-lactamase_P253K,beta-lactamase_253,TEM-1,beta-lactamase,P62593,0.885898,NO,253,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-2.253,-2.057,-0.196,5.24842,0.308,,B,0.73,-0.46,2.293,,73.08,BOP,-2.10633,0.221079,0.00786358,0.885898 hsp90_E590D,hsp90_590,hsp90,hsp90,P02829,0.885932,NO,590,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.818,-2.847,0,4.65049,0.021,H,A,,0.03,,,,HAO,-3.338,0.368192,0.000222939,0.885932 beta-lactamase_M153K,beta-lactamase_153,TEM-1,beta-lactamase,P62593,0.885936,NO,153,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-3.193,-3.777,0.584,5.46509,0.14,T,A,1.07,-0.11,2.061,,77.62,PHO,-2.25767,0.221079,0.00509109,0.885936 beta-lactamase_N168S,beta-lactamase_168,TEM-1,beta-lactamase,P62593,0.885979,NO,168,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-1.029,-2.37,1.341,5.42128,0.113,G,A,0.09,-0.4,1.211,,44.41,HPA,-1.13233,0.221079,0.00288667,0.885979 beta-lactamase_0_A170G,beta-lactamase_0_170,TEM-1,beta-lactamase_0,P62593,0.886006,NO,170,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.237,-1.884,0.647,,0.126,,L,0.46,-0.35,2.427,,64.69,AHH,-1.63267,0.0500837,0.00431903,0.886006 kka2_1:4_M178S,kka2_1:4_178,Kka2,kka2_1:4,P00552,0.886037,NO,178,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-3.206,-2.817,-0.389,,0.554,.,b,0.55,0.68,9.913,9.913,71.59,BHO,-2.154,0.168804,0.00717253,0.886037 beta-lactamase_625_A215Q,beta-lactamase_625_215,TEM-1,beta-lactamase_625,P62593,0.886112,NO,215,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.503,-2.998,1.495,,,,a,0.46,-0.93,3.583,,74.48,HHO,-1.42633,0.213352,0.00544007,0.886112 Pab1_D138Q,Pab1_138,Pab1,Pab1,P04147,0.886115,NO,138,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.128,-3.415,2.287,,0.427,,B,,-0.03,,,,HAP,-1.13967,0.175299,0.000567877,0.886115 beta-lactamase_0_L218G,beta-lactamase_0_218,TEM-1,beta-lactamase_0,P62593,0.886121,NO,218,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.391,-3.644,2.253,,,I,b,0.55,-0.53,28.707,28.707,74.48,OHH,-1.58867,0.0500837,0.00618274,0.886121 beta-lactamase_625_C75M,beta-lactamase_625_75,TEM-1,beta-lactamase_625,P62593,0.886146,NO,75,C,M,CM,Special,Hydrophobic,5.07,5.74,0.67,196,121,149,28,108.5,162.9,54.4,-1.245,-4.597,3.352,,,H,A,0.46,-0.87,2.141,,50,HOO,-1.24333,0.213352,0.0034616,0.886146 beta-lactamase_39_I229E,beta-lactamase_39_229,TEM-1,beta-lactamase_39,P62593,0.886184,NO,229,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.267,-3.864,2.597,,0.083,E,B,0.48,-0.76,1.114,,50,HHH,-1.58767,0.0495842,0.00477249,0.886184 Pab1_T145I,Pab1_145,Pab1,Pab1,P04147,0.886211,NO,145,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.067,-3.377,2.31,,0.237,H,A,0.3,0.69,,,,APH,-1.135,0.175299,0.000331088,0.886211 kka2_1:1_R177Y,kka2_1:1_177,Kka2,kka2_1:1,P00552,0.886288,NO,177,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.282,-4.382,2.1,,0.521,T,A,1.2,0.16,1.842,,63.64,HBH,-2.36967,0.520039,0.00768224,0.886288 beta-lactamase_G85C,beta-lactamase_85,TEM-1,beta-lactamase,P62593,0.886316,NO,85,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.011,-5.172,4.161,5.58951,0.805,T,l,0.23,1.7,1.468,,63.64,HOP,-1.68733,0.221079,0.00252173,0.886316 kka2_1:1_A248R,kka2_1:1_248,Kka2,kka2_1:1,P00552,0.886316,NO,248,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.124,-2.856,0.732,,0.825,S,b,0.46,0.46,24.72,24.72,92.05,HHO,-2.15,0.520039,0.0125484,0.886316 kka2_1:8_N200F,kka2_1:8_200,Kka2,kka2_1:8,P00552,0.886363,NO,200,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-2.446,-4.524,2.078,,0.756,T,L,0.43,-0.08,2.528,,64.39,APO,-2.08,0.100394,0.00838549,0.886363 kka2_1:8_N200F,kka2_1:8_200,Kka2,kka2_1:8,P00552,0.886363,NO,200,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-2.446,-4.524,2.078,,0.756,T,L,0.43,-0.08,2.528,,64.39,APO,-2.08,0.100394,0.00838549,0.886363 beta-lactamase_G154S,beta-lactamase_154,TEM-1,beta-lactamase,P62593,0.886372,NO,154,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.823,-3.197,2.374,5.40944,0.54,T,l,0.77,-0.56,2.283,,64.69,HOA,-1.635,0.221079,0.00180205,0.886372 kka2_1:1_D180Y,kka2_1:1_180,Kka2,kka2_1:1,P00552,0.886384,NO,180,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.416,-3.544,1.128,,1.03,S,a,0.75,1.5,1.534,,71.59,OAO,-2.02933,0.520039,0.00756412,0.886384 kka2_1:8_Y218T,kka2_1:8_218,Kka2,kka2_1:8,P00552,0.886405,NO,218,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-1.438,-3.77,2.332,,0.122,H,A,1.25,-0.69,2.923,,56.06,BHP,-1.17533,0.100394,0.0126098,0.886405 kka2_1:8_Y218T,kka2_1:8_218,Kka2,kka2_1:8,P00552,0.886405,NO,218,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-1.438,-3.77,2.332,,0.122,H,A,1.25,-0.69,2.923,,56.06,BHP,-1.17533,0.100394,0.0126098,0.886405 kka2_1:2_G10D,kka2_1:2_10,Kka2,kka2_1:2,P00552,0.886407,NO,10,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.921,-2.473,0.552,,,,,,,2.192,,71.59,HOP,-2.10733,0.295029,0.00289233,0.886407 beta-lactamase_0_I45P,beta-lactamase_0_45,TEM-1,beta-lactamase_0,P62593,0.886447,NO,45,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-2.421,-4.091,1.67,,,E,B,0.48,-0.3,1.375,,77.62,HHA,-2.30267,0.0500837,0.00452842,0.886447 beta-lactamase_625_I93Q,beta-lactamase_625_93,TEM-1,beta-lactamase_625,P62593,0.886458,NO,93,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.401,-4.315,2.914,,0.128,E,B,0.48,0.44,1.524,,67.83,BHB,-1.873,0.213352,0.00527066,0.886458 kka2_1:8_T130P,kka2_1:8_130,Kka2,kka2_1:8,P00552,0.886591,NO,130,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.392,-4.046,1.654,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.100394,0.00804204,0.886591 kka2_1:8_T130P,kka2_1:8_130,Kka2,kka2_1:8,P00552,0.886591,NO,130,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.392,-4.046,1.654,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.100394,0.00804204,0.886591 beta-lactamase_D48A,beta-lactamase_48,TEM-1,beta-lactamase,P62593,0.886599,NO,48,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.101,-2.565,1.464,4.89966,0.189,E,B,0.23,0.21,1.281,,50.35,HAH,-1.62467,0.221079,0.0027273,0.886599 beta-lactamase_L188Y,beta-lactamase_188,TEM-1,beta-lactamase,P62593,0.88665,NO,188,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.166,-3.998,2.832,5.55434,,H,A,1.07,-0.3,1.574,,60.14,PHB,-1.47033,0.221079,0.00295687,0.88665 beta-lactamase_0_M209E,beta-lactamase_0_209,TEM-1,beta-lactamase_0,P62593,0.886667,NO,209,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.442,-3.84,2.398,,,H,A,0.55,-0.97,3.876,,64.69,HHA,-1.52633,0.0500837,0.00625021,0.886667 kka2_1:2_G210Q,kka2_1:2_210,Kka2,kka2_1:2,P00552,0.886696,NO,210,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.095,-4.139,3.044,,0.103,T,A,0.29,-0.62,0.271,,50,OOB,-0.966667,0.295029,0.00598378,0.886696 beta-lactamase_L167A,beta-lactamase_167,TEM-1,beta-lactamase,P62593,0.886745,NO,167,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.138,-3.097,1.959,5.13111,0.015,G,A,0.08,-0.63,0.4,,64.69,AHP,-1.30767,0.221079,0.00303566,0.886745 kka2_1:8_D183G,kka2_1:8_183,Kka2,kka2_1:8,P00552,0.886757,NO,183,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.204,-3.336,2.132,,0.518,.,b,0.75,0.25,0.347,,52.27,AAH,-1.40533,0.100394,0.00426304,0.886757 kka2_1:8_D183G,kka2_1:8_183,Kka2,kka2_1:8,P00552,0.886757,NO,183,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.204,-3.336,2.132,,0.518,.,b,0.75,0.25,0.347,,52.27,AAH,-1.40533,0.100394,0.00426304,0.886757 beta-lactamase_T107L,beta-lactamase_107,TEM-1,beta-lactamase,P62593,0.886767,NO,107,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.117,-3.237,2.12,5.23432,,G,A,2.12,-0.06,3.676,,67.83,HPA,-1.265,0.221079,0.00239347,0.886767 beta-lactamase_0_R59K,beta-lactamase_0_59,TEM-1,beta-lactamase_0,P62593,0.886768,NO,59,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.345,-2.351,1.006,,0.329,S,L,1.2,-0.09,2.919,,73.08,HBO,-2.24267,0.0500837,0.00318082,0.886768 kka2_1:8_D159R,kka2_1:8_159,Kka2,kka2_1:8,P00552,0.88678,NO,159,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.82,-3.995,3.175,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.100394,0.0030485,0.88678 kka2_1:8_D159R,kka2_1:8_159,Kka2,kka2_1:8,P00552,0.88678,NO,159,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.82,-3.995,3.175,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.100394,0.0030485,0.88678 beta-lactamase_0_L73E,beta-lactamase_0_73,TEM-1,beta-lactamase_0,P62593,0.886785,NO,73,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.507,-3.924,2.417,,,H,A,0.55,-0.64,0.877,,67.83,HHH,-1.487,0.0500837,0.00488983,0.886785 beta-lactamase_2500_T126V,beta-lactamase_2500_126,TEM-1,beta-lactamase_2500,P62593,0.886834,NO,126,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.122,-3.336,2.214,,0.05,H,A,0.22,-0.05,0.817,,44.41,HPH,-1.60467,0.361275,0.00244552,0.886834 beta-lactamase_0_L205F,beta-lactamase_0_205,TEM-1,beta-lactamase_0,P62593,0.886837,NO,205,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.922,-2.306,1.384,,,H,A,0.55,-0.46,1.065,,42.31,PHH,-1.57767,0.0500837,0.00255802,0.886837 beta-lactamase_Y44I,beta-lactamase_44,TEM-1,beta-lactamase,P62593,0.886847,NO,44,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-2.547,-2.364,-0.183,5.6273,,E,B,2.55,-0.45,2.683,,73.78,OHH,-1.86267,0.221079,0.00426364,0.886847 kka2_1:4_G99E,kka2_1:4_99,Kka2,kka2_1:4,P00552,0.886849,NO,99,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.596,-3.693,3.097,,0.368,S,g,0.29,-0.87,,,,OOP,-1.63067,0.168804,0.00186055,0.886849 kka2_1:4_S54R,kka2_1:4_54,Kka2,kka2_1:4,P00552,0.886868,NO,54,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.471,-2.798,0.327,,0.408,S,b,0.27,1.01,17.332,17.332,71.59,HPO,-2.259,0.168804,0.00782867,0.886868 kka2_1:1_L165M,kka2_1:1_165,Kka2,kka2_1:1,P00552,0.886876,NO,165,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-2.453,-2.818,0.365,,0.299,,B,1.59,1.12,2.47,,64.39,OHH,-1.90967,0.520039,0.00801161,0.886876 kka2_1:8_Y244N,kka2_1:8_244,Kka2,kka2_1:8,P00552,0.886943,NO,244,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-0.775,-3.926,3.151,,0.066,H,A,1.25,-0.64,,,,HHO,-1.41267,0.100394,0.00453187,0.886943 kka2_1:8_Y244N,kka2_1:8_244,Kka2,kka2_1:8,P00552,0.886943,NO,244,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-0.775,-3.926,3.151,,0.066,H,A,1.25,-0.64,,,,HHO,-1.41267,0.100394,0.00453187,0.886943 kka2_1:2_G43M,kka2_1:2_43,Kka2,kka2_1:2,P00552,0.887048,NO,43,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.587,-4.94,3.353,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.295029,0.0071925,0.887048 Pab1_H134M,Pab1_134,Pab1,Pab1,P04147,0.887061,NO,134,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-1.542,-4.692,3.15,,,,,,,,,,HBO,-1.346,0.175299,0.00116356,0.887061 kka2_1:1_D33Q,kka2_1:1_33,Kka2,kka2_1:1,P00552,0.887085,NO,33,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.186,-3.005,0.819,,0.561,S,A,0.75,3.35,2.568,,71.59,PAH,-1.306,0.520039,0.00633568,0.887085 hsp90_G584C,hsp90_584,hsp90,hsp90,P02829,0.887094,NO,584,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-2.511,-4.015,0,5.20094,0.414,S,b,0.84,0.33,,,,HOH,-3.32733,0.368192,0.000222939,0.887094 Ubiquitin_A46H,Ubiquitin_46,Uba1,Ubiquitin,P0CG48,0.887097,NO,46,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.77,-4.653,2.883,5.38761,0.398,T,L,2.34,-0.8,6.506,,51.09,HHO,-1.505,0.205827,0.000581142,0.887097 Ubiquitin_D32C,Ubiquitin_32,Uba1,Ubiquitin,P0CG48,0.887097,NO,32,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.451,-5.087,3.636,4.96502,0.835,H,A,,1.4,,,,PAB,-1.47067,0.205827,0.000758819,0.887097 Ubiquitin_D58Q,Ubiquitin_58,Uba1,Ubiquitin,P0CG48,0.887097,NO,58,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.622,-3.9,2.278,5.06391,0.457,G,A,,-0.54,,,,PAH,-1.60267,0.205827,0.000639847,0.887097 Ubiquitin_E64I,Ubiquitin_64,Uba1,Ubiquitin,P0CG48,0.887097,NO,64,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.763,-4.006,2.243,5.084,0.54,T,l,,0.79,,,,BAP,-1.64433,0.205827,0.000817406,0.887097 Ubiquitin_G35H,Ubiquitin_35,Uba1,Ubiquitin,P0CG48,0.887097,NO,35,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.171,-4.571,3.4,4.96213,0.713,,L,,0.2,,,,AOH,-1.314,0.205827,0.000648878,0.887097 Ubiquitin_G35M,Ubiquitin_35,Uba1,Ubiquitin,P0CG48,0.887097,NO,35,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.171,-3.101,1.93,4.96213,0.713,,L,,0.2,,,,AOH,-1.314,0.205827,0.000648878,0.887097 Ubiquitin_I13G,Ubiquitin_13,Uba1,Ubiquitin,P0CG48,0.887097,NO,13,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.554,-3.776,2.222,5.19411,0.038,E,B,,-0.2,,,,PHP,-1.48,0.205827,0.000716423,0.887097 Ubiquitin_I30P,Ubiquitin_30,Uba1,Ubiquitin,P0CG48,0.887097,NO,30,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.205,-4.041,2.836,4.80264,,H,A,,-0.51,,,,BHP,-1.45133,0.205827,0.000720128,0.887097 Ubiquitin_K6G,Ubiquitin_6,Uba1,Ubiquitin,P0CG48,0.887097,NO,6,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.093,-3.371,2.278,4.84211,0.35,E,B,1.82,-0.62,1.502,,71.82,HBP,-1.36133,0.205827,0.000784795,0.887097 Ubiquitin_L43F,Ubiquitin_43,Uba1,Ubiquitin,P0CG48,0.887097,NO,43,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.269,-3.802,2.533,4.8799,,E,B,1.75,-1.17,10.246,10.246,53.87,BHH,-1.46867,0.205827,0.000572481,0.887097 Ubiquitin_Q40E,Ubiquitin_40,Uba1,Ubiquitin,P0CG48,0.887097,NO,40,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-1.752,-2.434,0.682,4.7807,0.387,G,A,,0.03,,,,APP,-1.62433,0.205827,0.000619089,0.887097 Ubiquitin_T22Q,Ubiquitin_22,Uba1,Ubiquitin,P0CG48,0.887097,NO,22,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.344,-3.861,2.517,4.54389,0.237,B,B,,-0.75,,,,APH,-1.28733,0.205827,0.000535592,0.887097 kka2_1:1_E63A,kka2_1:1_63,Kka2,kka2_1:1,P00552,0.887193,NO,63,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-0.762,-3.106,2.344,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.520039,0.00118399,0.887193 beta-lactamase_0_Y44A,beta-lactamase_0_44,TEM-1,beta-lactamase_0,P62593,0.887266,NO,44,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-2.547,-2.301,-0.246,,,E,B,0.21,-0.45,1.751,,73.78,OHH,-1.86267,0.0500837,0.00426364,0.887266 beta-lactamase_0_P172R,beta-lactamase_0_172,TEM-1,beta-lactamase_0,P62593,0.887273,NO,172,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.998,-3.96,2.962,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.0500837,0.00312594,0.887273 beta-lactamase_0_Q276R,beta-lactamase_0_276,TEM-1,beta-lactamase_0,P62593,0.887323,NO,276,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.0500837,0.0191712,0.887323 beta-lactamase_0_C75M,beta-lactamase_0_75,TEM-1,beta-lactamase_0,P62593,0.887332,NO,75,C,M,CM,Special,Hydrophobic,5.07,5.74,0.67,196,121,149,28,108.5,162.9,54.4,-1.245,-4.597,3.352,,,H,A,0.46,-0.87,2.256,,50,HOO,-1.24333,0.0500837,0.0034616,0.887332 beta-lactamase_0_L89C,beta-lactamase_0_89,TEM-1,beta-lactamase_0,P62593,0.887343,NO,89,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.096,-4.756,3.66,,0.168,T,A,0.55,0.63,2.373,,64.34,PHO,-1.75767,0.0500837,0.00207068,0.887343 kka2_1:2_Q27D,kka2_1:2_27,Kka2,kka2_1:2,P00552,0.887371,NO,27,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-1.659,-1.745,0.086,,0.608,.,A,0.64,0.71,0.521,,65.53,PPP,-1.90733,0.295029,0.00595365,0.887371 kka2_1:1_Q4T,kka2_1:1_4,Kka2,kka2_1:1,P00552,0.887397,NO,4,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.361,-3.156,0.795,,,,,,,5.615,,71.59,APA,-1.95533,0.520039,0.00239179,0.887397 beta-lactamase_625_G265F,beta-lactamase_625_265,TEM-1,beta-lactamase_625,P62593,0.887406,NO,265,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.213352,0.00811926,0.887406 kka2_1:4_A79W,kka2_1:4_79,Kka2,kka2_1:4,P00552,0.887453,NO,79,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.368,-5.595,3.227,,0.563,.,B,0.46,-0.43,2.291,,71.59,HHH,-1.752,0.168804,0.00664821,0.887453 kka2_1:1_A248T,kka2_1:1_248,Kka2,kka2_1:1,P00552,0.887455,NO,248,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.124,-3.092,0.968,,0.825,S,b,0.46,0.46,24.72,24.72,92.05,HHO,-2.15,0.520039,0.0125484,0.887455 kka2_1:8_P45G,kka2_1:8_45,Kka2,kka2_1:8,P00552,0.887465,NO,45,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.774,-2.532,0.758,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.100394,0.00590481,0.887465 kka2_1:8_P45G,kka2_1:8_45,Kka2,kka2_1:8,P00552,0.887465,NO,45,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.774,-2.532,0.758,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.100394,0.00590481,0.887465 beta-lactamase_0_R41F,beta-lactamase_0_41,TEM-1,beta-lactamase_0,P62593,0.887483,NO,41,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-0.942,-4.29,3.348,,0.321,E,B,1.2,-0.07,2.68,,65.03,HBH,-1.30267,0.0500837,0.00123327,0.887483 beta-lactamase_39_F64T,beta-lactamase_39_64,TEM-1,beta-lactamase_39,P62593,0.887521,NO,64,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-0.841,-3.646,2.805,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.0495842,0.000947691,0.887521 beta-lactamase_2500_A170F,beta-lactamase_2500_170,TEM-1,beta-lactamase_2500,P62593,0.887639,NO,170,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.237,-2.633,1.396,,0.126,,L,0.46,-0.35,2.427,,64.69,AHH,-1.63267,0.361275,0.00431903,0.887639 kka2_1:2_Q4H,kka2_1:2_4,Kka2,kka2_1:2,P00552,0.887646,NO,4,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.361,-4.16,1.799,,,,,,,2.026,,71.59,APA,-1.95533,0.295029,0.00239179,0.887646 beta-lactamase_0_F70P,beta-lactamase_0_70,TEM-1,beta-lactamase_0,P62593,0.887654,NO,70,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.169,-4.211,3.042,,,H,A,0.58,-1.34,2.153,,63.99,PHB,-0.980667,0.0500837,0.00193499,0.887654 beta-lactamase_0_G52P,beta-lactamase_0_52,TEM-1,beta-lactamase_0,P62593,0.887658,NO,52,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.149,-2.849,1.7,,0.299,,l,0.29,-0.04,1.164,,64.69,POB,-1.66267,0.0500837,0.00340138,0.887658 kka2_1:8_D156M,kka2_1:8_156,Kka2,kka2_1:8,P00552,0.887684,NO,156,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.696,-4.858,3.162,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.100394,0.00926998,0.887684 kka2_1:8_D156M,kka2_1:8_156,Kka2,kka2_1:8,P00552,0.887684,NO,156,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.696,-4.858,3.162,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.100394,0.00926998,0.887684 beta-lactamase_2500_R92S,beta-lactamase_2500_92,TEM-1,beta-lactamase_2500,P62593,0.887687,NO,92,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.718,-3.47,1.752,,0.479,E,B,1.2,1.36,3.069,,65.38,BBH,-1.50367,0.361275,0.00429626,0.887687 kka2_1:1_R143T,kka2_1:1_143,Kka2,kka2_1:1,P00552,0.887697,NO,143,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.525,-2.557,0.032,,0.325,H,A,0.16,1.22,3.6,,65.53,ABH,-1.86833,0.520039,0.00662247,0.887697 beta-lactamase_0_K32R,beta-lactamase_0_32,TEM-1,beta-lactamase_0,P62593,0.88772,NO,32,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.984,-2.38,0.396,,0.563,H,A,2.34,0.34,0.418,,73.08,HBA,-2.04233,0.0500837,0.00401283,0.88772 Pab1_Y197L,Pab1_197,Pab1,Pab1,P04147,0.887732,NO,197,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-1.345,-2.952,1.607,,,,,,,0.891,,80.42,HHH,-1.41767,0.175299,0.00302474,0.887732 beta-lactamase_R63S,beta-lactamase_63,TEM-1,beta-lactamase,P62593,0.887761,NO,63,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-0.943,-3.435,2.492,5.49979,0.218,,B,0.45,-0.31,0.677,,44.06,ABH,-0.992333,0.221079,0.00126938,0.887761 kka2_1:8_R140M,kka2_1:8_140,Kka2,kka2_1:8,P00552,0.887779,NO,140,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.351,-4.639,3.288,,0.12,H,A,0.16,0.2,2.874,,53.03,BBH,-1.885,0.100394,0.00430167,0.887779 kka2_1:8_R140M,kka2_1:8_140,Kka2,kka2_1:8,P00552,0.887779,NO,140,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.351,-4.639,3.288,,0.12,H,A,0.16,0.2,2.874,,53.03,BBH,-1.885,0.100394,0.00430167,0.887779 WW_domain_K181N,WW_domain_181,Yap65,WW_domain,P46937,0.887787,NO,181,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.35,-3.439,2.089,5.0864,,,,,,0.176,,15.87,HBP,-1.247,0.153962,0.0033022,0.887787 beta-lactamase_0_N134A,beta-lactamase_0_134,TEM-1,beta-lactamase_0,P62593,0.887798,NO,134,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-0.879,-3.3,2.421,,0.138,H,A,0.61,-0.6,3.776,,53.15,HPH,-1.02233,0.0500837,0.000644786,0.887798 gb1_G264N,gb1_264,gb1,gb1,P06654,0.88782,NO,264,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.833,-2.099,0.266,,,,,,,0.864,,44.87,POH,-1.61267,0.177985,0.0049716,0.88782 beta-lactamase_0_K144T,beta-lactamase_0_144,TEM-1,beta-lactamase_0,P62593,0.88784,NO,144,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-2.388,-2.935,0.547,,0.863,H,A,2.34,1.27,5.696,,77.62,OBA,-1.904,0.0500837,0.00481141,0.88784 beta-lactamase_0_L160K,beta-lactamase_0_160,TEM-1,beta-lactamase_0,P62593,0.887848,NO,160,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.977,-3.757,2.78,,0.022,,B,0.55,-0.6,0.68,,44.41,BHA,-0.936,0.0500837,0.00193775,0.887848 beta-lactamase_625_L49H,beta-lactamase_625_49,TEM-1,beta-lactamase_625,P62593,0.88785,NO,49,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.897,-4.794,2.897,,0.131,T,A,0.55,0.04,3.112,,64.69,AHP,-1.99233,0.213352,0.00401477,0.88785 beta-lactamase_G154N,beta-lactamase_154,TEM-1,beta-lactamase,P62593,0.887853,NO,154,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.823,-3.507,2.684,5.40944,0.54,T,l,0.77,-0.56,2.283,,64.69,HOA,-1.635,0.221079,0.00180205,0.887853 beta-lactamase_G194M,beta-lactamase_194,TEM-1,beta-lactamase,P62593,0.887853,NO,194,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.396,-4.893,3.497,5.46622,0.276,S,b,0.77,0.36,3.593,,67.83,POA,-1.832,0.221079,0.00392163,0.887853 beta-lactamase_H156M,beta-lactamase_156,TEM-1,beta-lactamase,P62593,0.887853,NO,156,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-3.156,-3.543,0.387,6.00284,0.753,S,A,0.72,-0.6,6.456,6.456,77.62,ABH,-1.932,0.221079,0.00468596,0.887853 beta-lactamase_L19E,beta-lactamase_19,TEM-1,beta-lactamase,P62593,0.887853,NO,19,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.682,-3.623,1.941,,,,,,,4.261,,93.01,OHO,-1.894,0.221079,0.00215974,0.887853 beta-lactamase_M153G,beta-lactamase_153,TEM-1,beta-lactamase,P62593,0.887853,NO,153,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-3.193,-3.633,0.44,5.46509,0.14,T,A,1.07,-0.11,2.061,,77.62,PHO,-2.25767,0.221079,0.00509109,0.887853 beta-lactamase_V31M,beta-lactamase_31,TEM-1,beta-lactamase,P62593,0.887853,NO,31,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.822,-3.184,1.362,5.43781,,H,A,2.78,-0.46,2.885,,73.78,BHB,-2.03767,0.221079,0.00478065,0.887853 beta-lactamase_0_N173Q,beta-lactamase_0_173,TEM-1,beta-lactamase_0,P62593,0.88786,NO,173,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-2.663,-4.003,1.34,,1.044,T,l,0.61,1.25,1.133,,77.62,OPA,-1.46633,0.0500837,0.0033769,0.88786 kka2_1:1_G55Q,kka2_1:1_55,Kka2,kka2_1:1,P00552,0.887865,NO,55,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.625,-4.083,2.458,,0.517,S,b,0.29,1.19,4.035,,63.64,POH,-2.05967,0.520039,0.00667877,0.887865 beta-lactamase_0_A183G,beta-lactamase_0_183,TEM-1,beta-lactamase_0,P62593,0.887916,NO,183,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.231,-3.077,1.846,,0.155,H,A,0.46,-0.91,1.48,,77.62,HHH,-1.53367,0.0500837,0.00296631,0.887916 beta-lactamase_2500_K30S,beta-lactamase_2500_30,TEM-1,beta-lactamase_2500,P62593,0.887942,NO,30,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-2.307,-3.277,0.97,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.361275,0.00448593,0.887942 beta-lactamase_S233A,beta-lactamase_233,TEM-1,beta-lactamase,P62593,0.888056,NO,233,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.886,-2.424,0.538,4.98121,0.016,E,B,0.48,-1.01,5.361,,77.62,BPO,-1.17267,0.221079,0.00311415,0.888056 beta-lactamase_V8G,beta-lactamase_8,TEM-1,beta-lactamase,P62593,0.888082,NO,8,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-2.358,-2.406,0.048,,,,,,,0.575,,77.62,BHH,-2.06267,0.221079,0.00226401,0.888082 beta-lactamase_0_I54H,beta-lactamase_0_54,TEM-1,beta-lactamase_0,P62593,0.888088,NO,54,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-2.838,-3.42,0.582,,0.669,E,B,0.48,-0.14,0.541,,73.78,BHH,-2.337,0.0500837,0.00403589,0.888088 beta-lactamase_0_M66W,beta-lactamase_0_66,TEM-1,beta-lactamase_0,P62593,0.888096,NO,66,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.362,-5.087,3.725,,0.013,,A,0.55,-0.7,1.204,,73.08,OHH,-1.49567,0.0500837,0.00412876,0.888096 WW_domain_T198S,WW_domain_198,Yap65,WW_domain,P46937,0.888106,NO,198,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.451,-2.94,1.489,5.14348,,,,,,3.158,,70.04,PPH,-1.513,0.153962,0.00224534,0.888106 beta-lactamase_156_S51P,beta-lactamase_156_51,TEM-1,beta-lactamase_156,P62593,0.888123,NO,51,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.526,-3.858,2.332,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.111618,0.00504821,0.888123 kka2_1:8_A144C,kka2_1:8_144,Kka2,kka2_1:8,P00552,0.888183,NO,144,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.859,-4.523,3.664,,,H,A,1.04,0.21,1.118,,52.65,BHB,-1.72933,0.100394,0.00231095,0.888183 kka2_1:8_A144C,kka2_1:8_144,Kka2,kka2_1:8,P00552,0.888183,NO,144,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.859,-4.523,3.664,,,H,A,1.04,0.21,1.118,,52.65,BHB,-1.72933,0.100394,0.00231095,0.888183 beta-lactamase_2500_E46V,beta-lactamase_2500_46,TEM-1,beta-lactamase_2500,P62593,0.888185,NO,46,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.94,-1.834,-0.106,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.361275,0.00427568,0.888185 kka2_1:8_L184P,kka2_1:8_184,Kka2,kka2_1:8,P00552,0.888238,NO,184,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.496,-2.724,1.228,,0.489,E,B,0.55,-0.06,4.495,,63.26,AHH,-1.24833,0.100394,0.00518742,0.888238 kka2_1:8_L184P,kka2_1:8_184,Kka2,kka2_1:8,P00552,0.888238,NO,184,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.496,-2.724,1.228,,0.489,E,B,0.55,-0.06,4.495,,63.26,AHH,-1.24833,0.100394,0.00518742,0.888238 kka2_1:2_L53D,kka2_1:2_53,Kka2,kka2_1:2,P00552,0.888344,NO,53,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-2.681,-2.935,0.254,,0.569,E,B,0.55,0.8,19.536,19.536,71.59,AHP,-2.47433,0.295029,0.00671168,0.888344 beta-lactamase_L55Q,beta-lactamase_55,TEM-1,beta-lactamase,P62593,0.888378,NO,55,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.86,-3.156,1.296,,0.372,E,A,1.07,-0.36,1.423,,63.99,HHA,-2.247,0.221079,0.00403741,0.888378 beta-lactamase_0_D231G,beta-lactamase_0_231,TEM-1,beta-lactamase_0,P62593,0.888418,NO,231,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.816,-3.182,2.366,,,E,B,0.75,-1.06,4.975,,65.38,HAB,-0.994,0.0500837,0.00107395,0.888418 beta-lactamase_T187L,beta-lactamase_187,TEM-1,beta-lactamase,P62593,0.888445,NO,187,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.401,-2.278,0.877,5.11453,0.007,H,A,0.3,-1.19,1.751,,67.48,PPH,-1.69633,0.221079,0.00491782,0.888445 kka2_1:2_S68I,kka2_1:2_68,Kka2,kka2_1:2,P00552,0.888466,NO,68,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.623,-4.041,1.418,,0.48,H,A,0.27,-0.1,2.655,,71.59,HPH,-1.40767,0.295029,0.00608265,0.888466 kka2_1:4_L212V,kka2_1:4_212,Kka2,kka2_1:4,P00552,0.888493,NO,212,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.904,-2.413,1.509,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.168804,0.0031426,0.888493 beta-lactamase_W208M,beta-lactamase_208,TEM-1,beta-lactamase,P62593,0.888504,NO,208,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-0.818,-4.48,3.662,5.26277,0.067,H,A,0.99,-0.65,,,,AHH,-1.44133,0.221079,0.00126609,0.888504 beta-lactamase_0_F64H,beta-lactamase_0_64,TEM-1,beta-lactamase_0,P62593,0.888511,NO,64,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-0.841,-4.455,3.614,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.0500837,0.000947691,0.888511 beta-lactamase_E56C,beta-lactamase_56,TEM-1,beta-lactamase,P62593,0.888561,NO,56,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.043,-4.827,2.784,5.65281,0.198,E,B,0.52,0.31,2.022,,72.73,HAP,-1.94033,0.221079,0.00238534,0.888561 beta-lactamase_K53C,beta-lactamase_53,TEM-1,beta-lactamase,P62593,0.888561,NO,53,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-2.313,-5.135,2.822,5.93654,0.589,,B,1.82,1.15,19.72,19.72,77.62,OBH,-2.1,0.221079,0.00383383,0.888561 Pab1_A179T,Pab1_179,Pab1,Pab1,P04147,0.888633,NO,179,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.013,-3.014,2.001,,0.078,H,A,0.61,0.5,,,,HHB,-1.51233,0.175299,0.000291703,0.888633 beta-lactamase_0_E26N,beta-lactamase_0_26,TEM-1,beta-lactamase_0,P62593,0.888671,NO,26,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.454,-3.711,1.257,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.0500837,0.00297948,0.888671 beta-lactamase_0_K213F,beta-lactamase_0_213,TEM-1,beta-lactamase_0,P62593,0.888745,NO,213,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.81,-4.437,2.627,,0.67,,A,2.34,0.29,3.015,,67.83,ABH,-1.57767,0.0500837,0.00610411,0.888745 kka2_1:4_E235G,kka2_1:4_235,Kka2,kka2_1:4,P00552,0.888798,NO,235,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.955,-2.889,0.934,,0.631,H,A,1.04,0.12,23.175,23.175,65.53,OAH,-2.07267,0.168804,0.0102806,0.888798 beta-lactamase_E56L,beta-lactamase_56,TEM-1,beta-lactamase,P62593,0.888811,NO,56,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.043,-3.398,1.355,5.65281,0.198,E,B,0.52,0.31,2.022,,72.73,HAP,-1.94033,0.221079,0.00238534,0.888811 beta-lactamase_P20S,beta-lactamase_20,TEM-1,beta-lactamase,P62593,0.888811,NO,20,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.74,-3.21,1.47,,,,,,,0.368,,67.83,HOH,-1.765,0.221079,0.00235322,0.888811 beta-lactamase_0_G142K,beta-lactamase_0_142,TEM-1,beta-lactamase_0,P62593,0.88882,NO,142,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.707,-3.645,2.938,,0.034,,p,0.29,-0.64,1.947,,64.69,OOO,-0.834,0.0500837,0.00060149,0.88882 kka2_1:1_R143H,kka2_1:1_143,Kka2,kka2_1:1,P00552,0.888836,NO,143,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.525,-3.575,1.05,,0.325,H,A,0.16,1.22,3.6,,65.53,ABH,-1.86833,0.520039,0.00662247,0.888836 beta-lactamase_0_P181T,beta-lactamase_0_181,TEM-1,beta-lactamase_0,P62593,0.88887,NO,181,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.813,-3.419,2.606,,,H,A,0.52,-1.14,1.357,,61.54,HOH,-1.795,0.0500837,0.000703122,0.88887 Pab1_A179L,Pab1_179,Pab1,Pab1,P04147,0.888922,NO,179,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.013,-2.95,1.937,,0.078,H,A,0.61,0.5,,,,HHB,-1.51233,0.175299,0.000291703,0.888922 kka2_1:4_G43V,kka2_1:4_43,Kka2,kka2_1:4,P00552,0.888923,NO,43,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.587,-3.838,2.251,,0.862,T,l,0.75,-0.67,2.247,,63.26,POB,-2.18533,0.168804,0.0071925,0.888923 beta-lactamase_0_H151R,beta-lactamase_0_151,TEM-1,beta-lactamase_0,P62593,0.888933,NO,151,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-2.96,-1.217,-1.743,,0.594,H,A,0.17,0.1,9.375,,77.62,HBP,-2.34767,0.0500837,0.00216946,0.888933 beta-lactamase_39_S104F,beta-lactamase_39_104,TEM-1,beta-lactamase_39,P62593,0.888952,NO,104,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.015,-4.127,3.112,,0.04,,b,0.27,0.57,4.02,,63.29,HPO,-1.05267,0.0495842,0.00218083,0.888952 beta-lactamase_M67Q,beta-lactamase_67,TEM-1,beta-lactamase,P62593,0.888968,NO,67,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-2.231,-4.09,1.859,4.9618,0.006,G,P,1.07,-0.81,1.463,,65.03,HHP,-1.502,0.221079,0.00409753,0.888968 kka2_1:8_G95C,kka2_1:8_95,Kka2,kka2_1:8,P00552,0.889069,NO,95,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-2.403,-5.049,2.646,,0.126,E,B,0.75,-0.74,7.774,,71.59,HOA,-2.198,0.100394,0.00743616,0.889069 kka2_1:8_G95C,kka2_1:8_95,Kka2,kka2_1:8,P00552,0.889069,NO,95,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-2.403,-5.049,2.646,,0.126,E,B,0.75,-0.74,7.774,,71.59,HOA,-2.198,0.100394,0.00743616,0.889069 beta-lactamase_0_G154Y,beta-lactamase_0_154,TEM-1,beta-lactamase_0,P62593,0.889102,NO,154,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.823,-4.424,3.601,,0.54,T,l,0.29,-0.56,3.629,,64.69,HOA,-1.635,0.0500837,0.00180205,0.889102 beta-lactamase_0_W208S,beta-lactamase_0_208,TEM-1,beta-lactamase_0,P62593,0.889139,NO,208,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-0.818,-3.836,3.018,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.0500837,0.00126609,0.889139 beta-lactamase_M127N,beta-lactamase_127,TEM-1,beta-lactamase,P62593,0.889156,NO,127,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-2.251,-4.047,1.796,5.40552,0.312,S,A,1.07,0.32,1.671,,72.73,PHP,-1.40433,0.221079,0.00437927,0.889156 PSD95pdz3_E331C,PSD95pdz3_331,PSD95pdz3,PSD95pdz3,P31016,0.889195,NO,331,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.404,-4.994,3.59,5.86289,,,,,51.8889,,,,OAA,-1.22533,0.0758425,0.000950134,0.889195 beta-lactamase_156_L73W,beta-lactamase_156_73,TEM-1,beta-lactamase_156,P62593,0.889226,NO,73,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.507,-5.171,3.664,,,H,A,0.55,-0.64,2.09,,67.83,HHH,-1.487,0.111618,0.00488983,0.889226 kka2_1:4_G95C,kka2_1:4_95,Kka2,kka2_1:4,P00552,0.889233,NO,95,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-2.403,-5.049,2.646,,0.126,E,B,0.29,-0.74,0.359,,71.59,HOA,-2.198,0.168804,0.00743616,0.889233 kka2_1:1_P76R,kka2_1:1_76,Kka2,kka2_1:1,P00552,0.889301,NO,76,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.449,-4.026,2.577,,0.331,.,B,0.52,-0.41,0.345,,63.64,HOO,-1.662,0.520039,0.00625685,0.889301 beta-lactamase_0_Y44E,beta-lactamase_0_44,TEM-1,beta-lactamase_0,P62593,0.889303,NO,44,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-2.547,-3.866,1.319,,,E,B,0.21,-0.45,1.751,,73.78,OHH,-1.86267,0.0500837,0.00426364,0.889303 kka2_1:8_E182T,kka2_1:8_182,Kka2,kka2_1:8,P00552,0.889322,NO,182,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.516,-2.525,1.009,,0.326,,B,1.52,0.75,2.568,,65.53,OAA,-1.806,0.100394,0.00641548,0.889322 kka2_1:8_E182T,kka2_1:8_182,Kka2,kka2_1:8,P00552,0.889322,NO,182,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.516,-2.525,1.009,,0.326,,B,1.52,0.75,2.568,,65.53,OAA,-1.806,0.100394,0.00641548,0.889322 beta-lactamase_H110S,beta-lactamase_110,TEM-1,beta-lactamase,P62593,0.889333,NO,110,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-1.706,-3.537,1.831,5.52635,0.341,G,a,0.35,1.08,31.31,31.31,64.69,BBH,-1.73333,0.221079,0.00441499,0.889333 beta-lactamase_L49C,beta-lactamase_49,TEM-1,beta-lactamase,P62593,0.889333,NO,49,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.897,-4.929,3.032,5.86005,0.131,T,A,1.3,0.04,3.112,,64.69,AHP,-1.99233,0.221079,0.00401477,0.889333 kka2_1:4_A119C,kka2_1:4_119,Kka2,kka2_1:4,P00552,0.889333,NO,119,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.073,-4.641,3.568,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.168804,0.00441074,0.889333 beta-lactamase_D161E,beta-lactamase_161,TEM-1,beta-lactamase,P62593,0.889384,NO,161,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.891,-2.299,1.408,5.12208,0.341,,A,0.23,-0.52,1.602,,61.19,HAB,-0.961333,0.221079,0.000897697,0.889384 kka2_1:2_A255C,kka2_1:2_255,Kka2,kka2_1:2,P00552,0.889393,NO,255,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.715,-5.069,3.354,,0.466,H,A,0.46,-0.52,5.144,,65.53,HHH,-1.71267,0.295029,0.0126809,0.889393 beta-lactamase_0_Y103C,beta-lactamase_0_103,TEM-1,beta-lactamase_0,P62593,0.889401,NO,103,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-1.33,-5.047,3.717,,0.613,S,l,0.21,1.21,1.646,,63.29,AHP,-1.48767,0.0500837,0.00443048,0.889401 WW_domain_S183L,WW_domain_183,Yap65,WW_domain,P46937,0.889413,NO,183,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.95,-3.373,1.423,5.35576,,,,,,1.594,,83.93,PPP,-1.48733,0.153962,0.00445513,0.889413 E1_Ubiquitin_R42W,E1_Ubiquitin_42,Uba1,E1_Ubiquitin,P0CG63,0.889478,NO,42,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.302,-5.193,3.891,,0.244,E,B,,-0.54,,,,PBH,-1.24667,0.18783,0.00224033,0.889478 beta-lactamase_0_K144H,beta-lactamase_0_144,TEM-1,beta-lactamase_0,P62593,0.889483,NO,144,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-2.388,-3.395,1.007,,0.863,H,A,2.34,1.27,5.696,,77.62,OBA,-1.904,0.0500837,0.00481141,0.889483 WW_domain_T196K,WW_domain_196,Yap65,WW_domain,P46937,0.889506,NO,196,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.782,-2.435,0.653,5.5744,,,,,,5.836,,70.04,PPP,-1.732,0.153962,0.00421377,0.889506 kka2_1:2_V214G,kka2_1:2_214,Kka2,kka2_1:2,P00552,0.889524,NO,214,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.261,-3.813,2.552,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.295029,0.00692782,0.889524 beta-lactamase_0_R242C,beta-lactamase_0_242,TEM-1,beta-lactamase_0,P62593,0.889561,NO,242,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.0500837,0.00452879,0.889561 beta-lactamase_0_P60I,beta-lactamase_0_60,TEM-1,beta-lactamase_0,P62593,0.889567,NO,60,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-2.469,-3.895,1.426,,0.256,T,A,0.52,-0.56,3.653,,77.62,BOA,-1.97633,0.0500837,0.00521318,0.889567 kka2_1:2_A56F,kka2_1:2_56,Kka2,kka2_1:2,P00552,0.889592,NO,56,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.083,-4.441,2.358,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.295029,0.00717715,0.889592 beta-lactamase_0_R81Y,beta-lactamase_0_81,TEM-1,beta-lactamase_0,P62593,0.889596,NO,81,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.466,-4.271,2.805,,0.218,H,A,1.2,1.66,0.332,,50,PBH,-1.60667,0.0500837,0.00499763,0.889596 beta-lactamase_Y95V,beta-lactamase_95,TEM-1,beta-lactamase,P62593,0.889607,NO,95,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-1.715,-2.446,0.731,5.67068,0.122,,b,0.96,-0.37,2.341,,77.62,BHP,-2.16167,0.221079,0.00479449,0.889607 kka2_1:2_S32V,kka2_1:2_32,Kka2,kka2_1:2,P00552,0.889631,NO,32,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-0.804,-3.557,2.753,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.295029,0.00149998,0.889631 beta-lactamase_0_Q204P,beta-lactamase_0_204,TEM-1,beta-lactamase_0,P62593,0.889655,NO,204,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-1.382,-3.857,2.475,,0.204,H,A,0.64,0.09,2.646,,66.08,PPH,-1.49067,0.0500837,0.00364106,0.889655 beta-lactamase_I243C,beta-lactamase_243,TEM-1,beta-lactamase,P62593,0.889662,NO,243,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.532,-4.934,3.402,5.26886,,E,B,1.68,-1.24,2.289,,50,OHH,-1.46867,0.221079,0.00464034,0.889662 beta-lactamase_R63I,beta-lactamase_63,TEM-1,beta-lactamase,P62593,0.889662,NO,63,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-0.943,-3.824,2.881,5.49979,0.218,,B,0.45,-0.31,0.677,,44.06,ABH,-0.992333,0.221079,0.00126938,0.889662 kka2_1:4_Q100G,kka2_1:4_100,Kka2,kka2_1:4,P00552,0.889664,NO,100,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.77,-3.044,0.274,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.168804,0.0066405,0.889664 kka2_1:8_G201C,kka2_1:8_201,Kka2,kka2_1:8,P00552,0.889713,NO,201,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.56,-3.58,2.02,,0.149,T,l,0.75,-0.57,2.152,,52.65,POB,-1.92233,0.100394,0.00820117,0.889713 kka2_1:8_G201C,kka2_1:8_201,Kka2,kka2_1:8,P00552,0.889713,NO,201,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.56,-3.58,2.02,,0.149,T,l,0.75,-0.57,2.152,,52.65,POB,-1.92233,0.100394,0.00820117,0.889713 PSD95pdz3_R318Y,PSD95pdz3_318,PSD95pdz3,PSD95pdz3,P31016,0.889718,NO,318,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.582,-3.844,2.262,4.94876,,,,,17.5609,,,,BBO,-1.40567,0.0758425,0.00110471,0.889718 beta-lactamase_0_T263L,beta-lactamase_0_263,TEM-1,beta-lactamase_0,P62593,0.889746,NO,263,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.0500837,0.0110582,0.889746 beta-lactamase_0_V82F,beta-lactamase_0_82,TEM-1,beta-lactamase_0,P62593,0.889769,NO,82,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.325,-3.991,2.666,,0.267,H,A,0.44,0.08,1.893,,93.01,BHA,-1.28567,0.0500837,0.00397046,0.889769 beta-lactamase_2500_L38I,beta-lactamase_2500_38,TEM-1,beta-lactamase_2500,P62593,0.889769,NO,38,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.343,-2.44,1.097,,0.088,H,A,0.55,0.2,2.71,,64.34,PHO,-1.78033,0.361275,0.00373244,0.889769 WW_domain_I193A,WW_domain_193,Yap65,WW_domain,P46937,0.88977,NO,193,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.993,-2.431,0.438,6.15906,,,,,,1.833,,83.33,BHA,-1.756,0.153962,0.00587613,0.88977 beta-lactamase_Q97C,beta-lactamase_97,TEM-1,beta-lactamase,P62593,0.889785,NO,97,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.072,-5.163,3.091,6.30204,0.823,G,A,1.1,2.42,1.157,,77.62,PPP,-2.43833,0.221079,0.0045116,0.889785 beta-lactamase_2500_E210A,beta-lactamase_2500_210,TEM-1,beta-lactamase_2500,P62593,0.88979,NO,210,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.319,-3.162,0.843,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.361275,0.00663582,0.88979 beta-lactamase_0_L192V,beta-lactamase_0_192,TEM-1,beta-lactamase_0,P62593,0.889839,NO,192,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.254,-1.986,0.732,,0.095,H,A,0.55,0.35,1.756,,60.14,HHP,-1.41833,0.0500837,0.00558728,0.889839 beta-lactamase_G39W,beta-lactamase_39,TEM-1,beta-lactamase,P62593,0.889889,NO,39,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.864,-5.517,3.653,5.35574,0.701,T,L,0.23,0.47,29.926,29.926,77.62,HOH,-1.53633,0.221079,0.00487611,0.889889 beta-lactamase_2500_F58R,beta-lactamase_2500_58,TEM-1,beta-lactamase_2500,P62593,0.88992,NO,58,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-2.914,-2.758,-0.156,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.361275,0.00523369,0.88992 beta-lactamase_0_L73R,beta-lactamase_0_73,TEM-1,beta-lactamase_0,P62593,0.889929,NO,73,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.507,-4.144,2.637,,,H,A,0.55,-0.64,0.877,,67.83,HHH,-1.487,0.0500837,0.00488983,0.889929 Pab1_F170H,Pab1_170,Pab1,Pab1,P04147,0.889944,NO,170,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.269,-4.114,2.845,,0.331,E,B,0.87,-1.31,2.061,,79.72,OHH,-1.06367,0.175299,0.000540225,0.889944 beta-lactamase_0_M153R,beta-lactamase_0_153,TEM-1,beta-lactamase_0,P62593,0.889982,NO,153,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-3.193,-4.075,0.882,,0.14,T,A,0.55,-0.11,3.826,,77.62,PHO,-2.25767,0.0500837,0.00509109,0.889982 beta-lactamase_0_S201I,beta-lactamase_0_201,TEM-1,beta-lactamase_0,P62593,0.890021,NO,201,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.183,-3.765,2.582,,0.064,H,A,0.27,-0.07,3.54,,64.69,HPB,-1.451,0.0500837,0.00198815,0.890021 kka2_1:8_L241T,kka2_1:8_241,Kka2,kka2_1:8,P00552,0.890057,NO,241,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.158,-3.592,2.434,,0.08,H,A,1.59,-0.82,1.136,,63.26,HHH,-1.58533,0.100394,0.0117299,0.890057 kka2_1:8_L241T,kka2_1:8_241,Kka2,kka2_1:8,P00552,0.890057,NO,241,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.158,-3.592,2.434,,0.08,H,A,1.59,-0.82,1.136,,63.26,HHH,-1.58533,0.100394,0.0117299,0.890057 gb1_E241G,gb1_241,gb1,gb1,P06654,0.890066,NO,241,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.672,-2.919,1.247,,,,,,,0.344,,11.83,OAP,-1.27933,0.177985,0.00250604,0.890066 gb1_V280M,gb1_280,gb1,gb1,P06654,0.890066,NO,280,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.764,-3.971,2.207,,,,,,,0.874,,35.71,PHP,-1.63733,0.177985,0.00321577,0.890066 beta-lactamase_S240C,beta-lactamase_240,TEM-1,beta-lactamase,P62593,0.890071,NO,240,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.537,-4.763,3.226,4.75024,,,B,0.74,-0.74,0.357,,65.38,OPB,-1.263,0.221079,0.00591201,0.890071 kka2_1:2_E235I,kka2_1:2_235,Kka2,kka2_1:2,P00552,0.890101,NO,235,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.955,-4.019,2.064,,0.631,H,A,1.04,0.12,26.048,26.048,65.53,OAH,-2.07267,0.295029,0.0102806,0.890101 kka2_1:2_A78P,kka2_1:2_78,Kka2,kka2_1:2,P00552,0.890124,NO,78,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.744,-0.97,-0.774,,0.078,.,B,0.46,-0.53,0.206,,56.06,OHH,-1.863,0.295029,0.00457299,0.890124 Pab1_D136K,Pab1_136,Pab1,Pab1,P04147,0.890142,NO,136,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.602,-3.437,1.835,,,,,,,,,,OAH,-1.42367,0.175299,0.00227029,0.890142 WW_domain_I193F,WW_domain_193,Yap65,WW_domain,P46937,0.890162,NO,193,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.993,-3.893,1.9,6.15906,,,,,,1.833,,83.33,BHA,-1.756,0.153962,0.00587613,0.890162 WW_domain_Q200T,WW_domain_200,Yap65,WW_domain,P46937,0.890167,NO,200,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-1.599,-3.31,1.711,5.37476,,,,,,1.9,,70.04,HPA,-1.484,0.153962,0.00300397,0.890167 Pab1_K140V,Pab1_140,Pab1,Pab1,P04147,0.890204,NO,140,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.083,-3.346,2.263,,0.345,H,A,,-0.73,,,,PBH,-1.20767,0.175299,0.000337366,0.890204 beta-lactamase_0_M67P,beta-lactamase_0_67,TEM-1,beta-lactamase_0,P62593,0.890235,NO,67,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-2.231,-4.072,1.841,,0.006,G,P,0.55,-0.81,24.165,24.165,65.03,HHP,-1.502,0.0500837,0.00409753,0.890235 beta-lactamase_V72A,beta-lactamase_72,TEM-1,beta-lactamase,P62593,0.890248,NO,72,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.658,-1.729,0.071,5.80324,,H,A,2.78,-1.03,2.964,,65.73,BHH,-1.32167,0.221079,0.00501194,0.890248 beta-lactamase_625_E119R,beta-lactamase_625_119,TEM-1,beta-lactamase_625,P62593,0.890279,NO,119,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.412,-3.743,2.331,,0.358,H,A,1.04,0.51,1.034,,63.99,BAH,-1.623,0.213352,0.00386966,0.890279 beta-lactamase_S201T,beta-lactamase_201,TEM-1,beta-lactamase,P62593,0.890307,NO,201,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.183,-3.198,2.015,4.85496,0.064,H,A,0.77,-0.07,4.045,,64.69,HPB,-1.451,0.221079,0.00198815,0.890307 Pab1_G193Y,Pab1_193,Pab1,Pab1,P04147,0.890328,NO,193,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.414,-4.272,2.858,,,,,,,,,,POP,-1.55733,0.175299,0.0014922,0.890328 kka2_1:4_W24M,kka2_1:4_24,Kka2,kka2_1:4,P00552,0.890349,NO,24,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-1.779,-3.383,1.604,,0.477,E,B,1.51,-0.21,2.666,,56.06,AHH,-2.24467,0.168804,0.00631564,0.890349 kka2_1:8_A237T,kka2_1:8_237,Kka2,kka2_1:8,P00552,0.890402,NO,237,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.12,-2.777,0.657,,0.068,H,A,0.46,-0.71,0.449,,92.05,HHA,-2.10433,0.100394,0.012257,0.890402 kka2_1:8_A237T,kka2_1:8_237,Kka2,kka2_1:8,P00552,0.890402,NO,237,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.12,-2.777,0.657,,0.068,H,A,0.46,-0.71,0.449,,92.05,HHA,-2.10433,0.100394,0.012257,0.890402 beta-lactamase_2500_K213Y,beta-lactamase_2500_213,TEM-1,beta-lactamase_2500,P62593,0.890429,NO,213,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.81,-4.305,2.495,,0.67,,A,2.34,0.29,1.668,,67.83,ABH,-1.57767,0.361275,0.00610411,0.890429 kka2_1:1_D23T,kka2_1:1_23,Kka2,kka2_1:1,P00552,0.89043,NO,23,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.459,-3.106,0.647,,0.695,E,B,0.75,-0.65,2.655,,65.53,HAH,-1.94033,0.520039,0.007195,0.89043 beta-lactamase_E56V,beta-lactamase_56,TEM-1,beta-lactamase,P62593,0.890464,NO,56,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.043,-3.397,1.354,5.65281,0.198,E,B,0.52,0.31,2.022,,72.73,HAP,-1.94033,0.221079,0.00238534,0.890464 beta-lactamase_0_A132R,beta-lactamase_0_132,TEM-1,beta-lactamase_0,P62593,0.89053,NO,132,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.9,-3.795,2.895,,,H,A,0.46,-0.93,2.249,,64.69,PHH,-1.138,0.0500837,0.000962524,0.89053 kka2_1:2_L158M,kka2_1:2_158,Kka2,kka2_1:2,P00552,0.890553,NO,158,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.947,-4.254,2.307,,0.095,,B,1.59,0.77,7.588,,63.64,AHA,-1.25333,0.295029,0.00529068,0.890553 beta-lactamase_P143H,beta-lactamase_143,TEM-1,beta-lactamase,P62593,0.890567,NO,143,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.967,-4.789,3.822,5.16366,0.075,H,A,0.99,-0.37,0.479,,66.78,OOB,-1.354,0.221079,0.00114551,0.890567 beta-lactamase_0_N168W,beta-lactamase_0_168,TEM-1,beta-lactamase_0,P62593,0.89058,NO,168,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-1.029,-5.48,4.451,,0.113,G,A,0.61,-0.4,0.881,,44.41,HPA,-1.13233,0.0500837,0.00288667,0.89058 beta-lactamase_2500_L38T,beta-lactamase_2500_38,TEM-1,beta-lactamase_2500,P62593,0.890585,NO,38,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.343,-3.495,2.152,,0.088,H,A,0.55,0.2,2.71,,64.34,PHO,-1.78033,0.361275,0.00373244,0.890585 beta-lactamase_2500_M180L,beta-lactamase_2500_180,TEM-1,beta-lactamase_2500,P62593,0.890596,NO,180,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-2.795,-3.19,0.395,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.361275,0.00552048,0.890596 beta-lactamase_0_T198R,beta-lactamase_0_198,TEM-1,beta-lactamase_0,P62593,0.890597,NO,198,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.168,-3.752,1.584,,0.489,,B,0.22,-0.13,9.874,,73.78,HPH,-1.98767,0.0500837,0.004311,0.890597 beta-lactamase_0_V31L,beta-lactamase_0_31,TEM-1,beta-lactamase_0,P62593,0.890627,NO,31,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.822,-2.16,0.338,,,H,A,0.44,-0.46,4.126,,73.78,BHB,-2.03767,0.0500837,0.00478065,0.890627 beta-lactamase_156_D48F,beta-lactamase_156_48,TEM-1,beta-lactamase_156,P62593,0.890706,NO,48,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.101,-4.285,3.184,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.111618,0.0027273,0.890706 Pab1_K180P,Pab1_180,Pab1,Pab1,P04147,0.890766,NO,180,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.945,-3.796,1.851,,,,,,,,,,HBA,-1.575,0.175299,0.00295933,0.890766 beta-lactamase_625_L197Q,beta-lactamase_625_197,TEM-1,beta-lactamase_625,P62593,0.890774,NO,197,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.853,-4.122,3.269,,0.007,S,B,0.55,0.33,1.756,,60.14,HHP,-1.833,0.213352,0.00144602,0.890774 beta-lactamase_2500_S51G,beta-lactamase_2500_51,TEM-1,beta-lactamase_2500,P62593,0.89078,NO,51,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.526,-2.569,1.043,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.361275,0.00504821,0.89078 beta-lactamase_2500_T198M,beta-lactamase_2500_198,TEM-1,beta-lactamase_2500,P62593,0.890796,NO,198,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.168,-4.608,2.44,,0.489,,B,0.22,-0.13,0.37,,73.78,HPH,-1.98767,0.361275,0.004311,0.890796 kka2_1:8_P109D,kka2_1:8_109,Kka2,kka2_1:8,P00552,0.890901,NO,109,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.412,-2.934,1.522,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.100394,0.0070929,0.890901 kka2_1:8_P109D,kka2_1:8_109,Kka2,kka2_1:8,P00552,0.890901,NO,109,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.412,-2.934,1.522,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.100394,0.0070929,0.890901 beta-lactamase_0_E175N,beta-lactamase_0_175,TEM-1,beta-lactamase_0,P62593,0.89091,NO,175,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.336,-3.857,1.521,,0.551,,A,1.04,1.05,2.334,,77.62,AAB,-1.31233,0.0500837,0.00482205,0.89091 kka2_1:8_L19R,kka2_1:8_19,Kka2,kka2_1:8,P00552,0.890952,NO,19,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.254,-4.143,2.889,,0.08,T,A,1.59,-0.26,2.044,,65.53,BHH,-2.221,0.100394,0.00620703,0.890952 kka2_1:8_L19R,kka2_1:8_19,Kka2,kka2_1:8,P00552,0.890952,NO,19,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.254,-4.143,2.889,,0.08,T,A,1.59,-0.26,2.044,,65.53,BHH,-2.221,0.100394,0.00620703,0.890952 beta-lactamase_T187I,beta-lactamase_187,TEM-1,beta-lactamase,P62593,0.890966,NO,187,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.401,-2.871,1.47,5.11453,0.007,H,A,0.3,-1.19,1.751,,67.48,PPH,-1.69633,0.221079,0.00491782,0.890966 PSD95pdz3_L353G,PSD95pdz3_353,PSD95pdz3,PSD95pdz3,P31016,0.891052,NO,353,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.347,-3.49,2.143,5.81136,,,,,17.3525,,,,AHB,-1.50533,0.0758425,0.000664742,0.891052 beta-lactamase_0_L284T,beta-lactamase_0_284,TEM-1,beta-lactamase_0,P62593,0.891105,NO,284,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.981,,,,0.848,H,A,2.89,0.67,4.544,,77.62,PHH,-1.82133,0.0500837,0.0686156,0.891105 beta-lactamase_A183W,beta-lactamase_183,TEM-1,beta-lactamase,P62593,0.89111,NO,183,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.231,-5.466,4.235,4.84712,0.155,H,A,0.55,-0.91,12.189,,77.62,HHH,-1.53367,0.221079,0.00296631,0.89111 beta-lactamase_A266Y,beta-lactamase_266,TEM-1,beta-lactamase,P62593,0.89111,NO,266,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.369,-4.265,2.896,5.02057,0.175,S,B,0.52,0.07,1.832,,64.34,PHP,-2.08567,0.221079,0.0140785,0.89111 beta-lactamase_C18V,beta-lactamase_18,TEM-1,beta-lactamase,P62593,0.89111,NO,18,C,V,CV,Special,Hydrophobic,5.07,5.60847,0.538465,192,121,117,-4,108.5,140,31.5,-2.26,-3.474,1.214,,,,,,,3.995,,93.01,HOH,-2.093,0.221079,0.002536,0.89111 beta-lactamase_E108W,beta-lactamase_108,TEM-1,beta-lactamase,P62593,0.89111,NO,108,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.46,-5.465,4.005,5.52079,0.572,G,A,0.52,1.87,1.973,,72.73,PAB,-1.437,0.221079,0.00413372,0.89111 beta-lactamase_L282F,beta-lactamase_282,TEM-1,beta-lactamase,P62593,0.89111,NO,282,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.586,-2.875,1.289,5.16743,0.007,H,A,1.07,0.34,31.31,31.31,63.99,PHH,-1.82367,0.221079,0.0449821,0.89111 beta-lactamase_L55C,beta-lactamase_55,TEM-1,beta-lactamase,P62593,0.89111,NO,55,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.86,-4.909,3.049,,0.372,E,A,1.07,-0.36,1.423,,63.99,HHA,-2.247,0.221079,0.00403741,0.89111 beta-lactamase_S122C,beta-lactamase_122,TEM-1,beta-lactamase,P62593,0.89111,NO,122,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.406,-5.091,2.685,4.87767,0.352,H,A,0.73,-0.54,1.581,,77.62,OPH,-1.39767,0.221079,0.00497825,0.89111 beta-lactamase_T139K,beta-lactamase_139,TEM-1,beta-lactamase,P62593,0.89111,NO,139,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.901,-3.403,1.502,5.69095,0.216,H,A,0.3,0.39,2.256,,77.62,PPH,-2.04667,0.221079,0.00441837,0.89111 beta-lactamase_T262W,beta-lactamase_262,TEM-1,beta-lactamase,P62593,0.89111,NO,262,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.332,-5.278,3.946,5.06002,0.108,E,B,0.3,-0.55,1.423,,67.83,PPO,-2.081,0.221079,0.00853516,0.89111 beta-lactamase_156_L192G,beta-lactamase_156_192,TEM-1,beta-lactamase_156,P62593,0.891122,NO,192,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.254,-3.698,2.444,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.111618,0.00558728,0.891122 kka2_1:4_H135M,kka2_1:4_135,Kka2,kka2_1:4,P00552,0.891231,NO,135,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-1.331,-4.614,3.283,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.168804,0.00532566,0.891231 beta-lactamase_0_E166F,beta-lactamase_0_166,TEM-1,beta-lactamase_0,P62593,0.891242,NO,166,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.756,-4.345,2.589,,0.508,G,A,1.04,1.05,17.227,17.227,73.08,OAH,-1.42233,0.0500837,0.00512989,0.891242 E1_Ubiquitin_R74C,E1_Ubiquitin_74,Uba1,E1_Ubiquitin,P0CG63,0.891247,NO,74,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.302,-4.958,3.656,,0.838,T,A,,3.15,,,,HBO,-1.11333,0.18783,0.00180798,0.891247 kka2_1:8_G88Y,kka2_1:8_88,Kka2,kka2_1:8,P00552,0.891272,NO,88,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.689,-4.408,2.719,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.100394,0.00685559,0.891272 kka2_1:8_G88Y,kka2_1:8_88,Kka2,kka2_1:8,P00552,0.891272,NO,88,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.689,-4.408,2.719,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.100394,0.00685559,0.891272 beta-lactamase_0_I261Q,beta-lactamase_0_261,TEM-1,beta-lactamase_0,P62593,0.891296,NO,261,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.0500837,0.0123091,0.891296 kka2_1:2_E161V,kka2_1:2_161,Kka2,kka2_1:2,P00552,0.891347,NO,161,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.581,-2.903,1.322,,0.829,G,A,1.52,2.24,1.612,,92.05,AAB,-1.861,0.295029,0.00760103,0.891347 kka2_1:1_L243E,kka2_1:1_243,Kka2,kka2_1:1,P00552,0.891394,NO,243,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-2.651,-2.717,0.066,,0.277,H,A,0.55,-0.67,4.334,,92.05,HHH,-2.03767,0.520039,0.00884927,0.891394 beta-lactamase_0_D48E,beta-lactamase_0_48,TEM-1,beta-lactamase_0,P62593,0.891401,NO,48,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.101,-2.049,0.948,,0.189,E,B,0.75,0.21,17.825,17.825,50.35,HAH,-1.62467,0.0500837,0.0027273,0.891401 beta-lactamase_625_S266V,beta-lactamase_625_266,TEM-1,beta-lactamase_625,P62593,0.891401,NO,266,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.213352,0.0140785,0.891401 beta-lactamase_2500_I261M,beta-lactamase_2500_261,TEM-1,beta-lactamase_2500,P62593,0.891408,NO,261,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.361275,0.0123091,0.891408 beta-lactamase_0_K286L,beta-lactamase_0_286,TEM-1,beta-lactamase_0,P62593,0.891419,NO,286,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.0500837,,0.891419 kka2_1:2_M148Q,kka2_1:2_148,Kka2,kka2_1:2,P00552,0.891421,NO,148,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.847,-4.147,2.3,,0.268,H,A,1.59,0.71,1.439,,64.39,BHA,-1.65467,0.295029,0.00982664,0.891421 beta-lactamase_0_S96E,beta-lactamase_0_96,TEM-1,beta-lactamase_0,P62593,0.891446,NO,96,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.27,-2.567,0.297,,0.368,,b,0.27,0.39,2.516,,73.78,HPP,-2.019,0.0500837,0.00551835,0.891446 beta-lactamase_625_R59A,beta-lactamase_625_59,TEM-1,beta-lactamase_625,P62593,0.891453,NO,59,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.345,-3.163,1.818,,0.329,S,L,1.2,-0.09,2.995,,73.08,HBO,-2.24267,0.213352,0.00318082,0.891453 beta-lactamase_0_S221N,beta-lactamase_0_221,TEM-1,beta-lactamase_0,P62593,0.891461,NO,221,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.754,-3.696,1.942,,0.624,H,A,0.27,-0.2,2.914,,74.48,BPH,-1.59967,0.0500837,0.0046094,0.891461 kka2_1:8_D90V,kka2_1:8_90,Kka2,kka2_1:8,P00552,0.891478,NO,90,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.459,-3.794,1.335,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.100394,0.00583842,0.891478 kka2_1:8_D90V,kka2_1:8_90,Kka2,kka2_1:8,P00552,0.891478,NO,90,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.459,-3.794,1.335,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.100394,0.00583842,0.891478 beta-lactamase_2500_L146I,beta-lactamase_2500_146,TEM-1,beta-lactamase_2500,P62593,0.89148,NO,146,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.462,-2.631,1.169,,0.007,H,A,0.55,-0.56,1.578,,64.69,AHP,-1.656,0.361275,0.00474542,0.89148 beta-lactamase_0_T116D,beta-lactamase_0_116,TEM-1,beta-lactamase_0,P62593,0.891492,NO,116,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.28,-3.524,2.244,,0.115,E,B,0.22,-0.12,1.356,,67.48,HPH,-1.39967,0.0500837,0.00336175,0.891492 kka2_1:8_S54I,kka2_1:8_54,Kka2,kka2_1:8,P00552,0.891615,NO,54,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.471,-2.562,0.091,,0.408,S,b,0.77,1.01,13.679,13.679,71.59,HPO,-2.259,0.100394,0.00782867,0.891615 kka2_1:8_S54I,kka2_1:8_54,Kka2,kka2_1:8,P00552,0.891615,NO,54,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.471,-2.562,0.091,,0.408,S,b,0.77,1.01,13.679,13.679,71.59,HPO,-2.259,0.100394,0.00782867,0.891615 beta-lactamase_0_G154E,beta-lactamase_0_154,TEM-1,beta-lactamase_0,P62593,0.891619,NO,154,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.823,-3.512,2.689,,0.54,T,l,0.29,-0.56,3.629,,64.69,HOA,-1.635,0.0500837,0.00180205,0.891619 gb1_T281D,gb1_281,gb1,gb1,P06654,0.891651,NO,281,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.828,-3.391,1.563,,,,,,,1.038,,35.71,HPA,-1.63667,0.177985,0.00284418,0.891651 kka2_1:2_A9S,kka2_1:2_9,Kka2,kka2_1:2,P00552,0.891665,NO,9,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.079,-2.471,0.392,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.295029,0.00273264,0.891665 beta-lactamase_0_L55Q,beta-lactamase_0_55,TEM-1,beta-lactamase_0,P62593,0.891684,NO,55,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.86,-3.156,1.296,,0.372,E,A,0.55,-0.36,1.967,,63.99,HHA,-2.247,0.0500837,0.00403741,0.891684 Pab1_N132T,Pab1_132,Pab1,Pab1,P04147,0.891758,NO,132,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-1.079,-3.014,1.935,,0.412,S,l,,0.9,,,,BPH,-1.067,0.175299,0.000347671,0.891758 kka2_1:8_G74V,kka2_1:8_74,Kka2,kka2_1:8,P00552,0.891775,NO,74,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.18,-3.881,2.701,,0.621,T,l,0.29,0.2,2.014,,64.39,POH,-1.91667,0.100394,0.00587035,0.891775 kka2_1:8_G74V,kka2_1:8_74,Kka2,kka2_1:8,P00552,0.891775,NO,74,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.18,-3.881,2.701,,0.621,T,l,0.29,0.2,2.014,,64.39,POH,-1.91667,0.100394,0.00587035,0.891775 beta-lactamase_0_D271C,beta-lactamase_0_271,TEM-1,beta-lactamase_0,P62593,0.891788,NO,271,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.0500837,0.00752082,0.891788 beta-lactamase_0_V72G,beta-lactamase_0_72,TEM-1,beta-lactamase_0,P62593,0.891815,NO,72,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.658,-3.477,1.819,,,H,A,0.44,-1.03,2.964,,65.73,BHH,-1.32167,0.0500837,0.00501194,0.891815 PSD95pdz3_R312I,PSD95pdz3_312,PSD95pdz3,PSD95pdz3,P31016,0.891843,NO,312,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.582,-3.692,2.11,5.76826,,,,,12.2409,,,,OBB,-1.46667,0.0758425,0.00196255,0.891843 beta-lactamase_156_R202D,beta-lactamase_156_202,TEM-1,beta-lactamase_156,P62593,0.891862,NO,202,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.292,-3.594,2.302,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.111618,0.00321899,0.891862 Pab1_L191Q,Pab1_191,Pab1,Pab1,P04147,0.891864,NO,191,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.2,-3.847,2.647,,0.204,E,B,,2.24,,,,HHP,-1.20133,0.175299,0.000583797,0.891864 kka2_1:4_Y218H,kka2_1:4_218,Kka2,kka2_1:4,P00552,0.891952,NO,218,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-1.438,-1.83,0.392,,0.122,H,A,0.21,-0.69,1.022,,56.06,BHP,-1.17533,0.168804,0.0126098,0.891952 beta-lactamase_2500_E145P,beta-lactamase_2500_145,TEM-1,beta-lactamase_2500,P62593,0.891963,NO,145,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.357,-3.914,1.557,,0.545,H,A,1.04,0.79,2.124,,77.62,BAH,-2.069,0.361275,0.00553285,0.891963 beta-lactamase_0_L284I,beta-lactamase_0_284,TEM-1,beta-lactamase_0,P62593,0.891992,NO,284,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.981,,,,0.848,H,A,2.89,0.67,4.544,,77.62,PHH,-1.82133,0.0500837,0.0686156,0.891992 kka2_1:2_D157Q,kka2_1:2_157,Kka2,kka2_1:2,P00552,0.892017,NO,157,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.993,-3.78,2.787,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.295029,0.0042313,0.892017 beta-lactamase_0_A235M,beta-lactamase_0_235,TEM-1,beta-lactamase_0,P62593,0.89202,NO,235,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.266,-4.612,3.346,,0.32,E,B,0.46,-0.86,2.261,,50,OHO,-0.89,0.0500837,0.00493474,0.89202 Pab1_K140S,Pab1_140,Pab1,Pab1,P04147,0.892028,NO,140,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.083,-2.978,1.895,,0.345,H,A,,-0.73,,,,PBH,-1.20767,0.175299,0.000337366,0.892028 beta-lactamase_156_V72F,beta-lactamase_156_72,TEM-1,beta-lactamase_156,P62593,0.892052,NO,72,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.658,-3.023,1.365,,,H,A,0.44,-1.03,1.92,,65.73,BHH,-1.32167,0.111618,0.00501194,0.892052 beta-lactamase_2500_F70S,beta-lactamase_2500_70,TEM-1,beta-lactamase_2500,P62593,0.892058,NO,70,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.169,-2.713,1.544,,,H,A,0.58,-1.34,1.918,,63.99,PHB,-0.980667,0.361275,0.00193499,0.892058 WW_domain_D201H,WW_domain_201,Yap65,WW_domain,P46937,0.892067,NO,201,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.369,-4.332,2.963,4.90312,,,,,,20.806,20.806,70.04,PAO,-1.456,0.153962,0.00248402,0.892067 beta-lactamase_2500_E119S,beta-lactamase_2500_119,TEM-1,beta-lactamase_2500,P62593,0.892074,NO,119,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.412,-2.681,1.269,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.361275,0.00386966,0.892074 PSD95pdz3_I359M,PSD95pdz3_359,PSD95pdz3,PSD95pdz3,P31016,0.892093,NO,359,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.63,-3.712,2.082,5.35151,,,,,14.8012,,,,PHH,-1.58667,0.0758425,0.000580694,0.892093 beta-lactamase_0_K144M,beta-lactamase_0_144,TEM-1,beta-lactamase_0,P62593,0.892116,NO,144,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-2.388,-4.736,2.348,,0.863,H,A,2.34,1.27,5.696,,77.62,OBA,-1.904,0.0500837,0.00481141,0.892116 beta-lactamase_E35Q,beta-lactamase_35,TEM-1,beta-lactamase,P62593,0.892139,NO,35,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-0.869,-3.292,2.423,5.10723,0.15,H,A,0.52,0.21,1.081,,46.85,HAA,-1.88667,0.221079,0.00174441,0.892139 kka2_1:2_A176P,kka2_1:2_176,Kka2,kka2_1:2,P00552,0.89214,NO,176,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.621,-3.934,2.313,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.295029,0.0083587,0.89214 beta-lactamase_0_M127K,beta-lactamase_0_127,TEM-1,beta-lactamase_0,P62593,0.892157,NO,127,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-2.251,-3,0.749,,0.312,S,A,0.55,0.32,9.35,9.35,72.73,PHP,-1.40433,0.0500837,0.00437927,0.892157 beta-lactamase_0_L28S,beta-lactamase_0_28,TEM-1,beta-lactamase_0,P62593,0.892165,NO,28,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.579,-3.523,1.944,,0.277,H,A,0.55,-0.16,9.35,9.35,93.01,PHH,-2.11333,0.0500837,0.00359321,0.892165 kka2_1:2_V97C,kka2_1:2_97,Kka2,kka2_1:2,P00552,0.892176,NO,97,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.453,-4.797,3.344,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.295029,0.00737869,0.892176 beta-lactamase_0_K144N,beta-lactamase_0_144,TEM-1,beta-lactamase_0,P62593,0.892201,NO,144,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-2.388,-3.043,0.655,,0.863,H,A,2.34,1.27,5.696,,77.62,OBA,-1.904,0.0500837,0.00481141,0.892201 beta-lactamase_0_I285N,beta-lactamase_0_285,TEM-1,beta-lactamase_0,P62593,0.892217,NO,285,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.0500837,0.101555,0.892217 beta-lactamase_2500_P25C,beta-lactamase_2500_25,TEM-1,beta-lactamase_2500,P62593,0.892232,NO,25,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.526,-5.046,3.52,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.361275,0.00347571,0.892232 beta-lactamase_2500_G253F,beta-lactamase_2500_253,TEM-1,beta-lactamase_2500,P62593,0.892267,NO,253,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.361275,0.00786358,0.892267 kka2_1:8_L170F,kka2_1:8_170,Kka2,kka2_1:8,P00552,0.89231,NO,170,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.28,-3.877,2.597,,0.029,H,A,1.59,0.11,1.453,,62.5,AHH,-1.534,0.100394,0.00730791,0.89231 kka2_1:8_L170F,kka2_1:8_170,Kka2,kka2_1:8,P00552,0.89231,NO,170,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.28,-3.877,2.597,,0.029,H,A,1.59,0.11,1.453,,62.5,AHH,-1.534,0.100394,0.00730791,0.89231 beta-lactamase_0_K32Y,beta-lactamase_0_32,TEM-1,beta-lactamase_0,P62593,0.892315,NO,32,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.984,-4.317,2.333,,0.563,H,A,2.34,0.34,0.418,,73.08,HBA,-2.04233,0.0500837,0.00401283,0.892315 kka2_1:1_A34R,kka2_1:1_34,Kka2,kka2_1:1,P00552,0.892467,NO,34,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.928,-3.768,2.84,,0.417,.,B,0.46,2.29,0.262,,52.27,AHH,-1.747,0.520039,0.00343484,0.892467 beta-lactamase_A183F,beta-lactamase_183,TEM-1,beta-lactamase,P62593,0.892506,NO,183,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.231,-4.164,2.933,4.84712,0.155,H,A,0.55,-0.91,12.189,,77.62,HHH,-1.53367,0.221079,0.00296631,0.892506 beta-lactamase_L10G,beta-lactamase_10,TEM-1,beta-lactamase,P62593,0.892506,NO,10,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.623,-3.608,1.985,,,,,,,2.467,,65.38,HHH,-1.83833,0.221079,0.00296968,0.892506 beta-lactamase_2500_Q203C,beta-lactamase_2500_203,TEM-1,beta-lactamase_2500,P62593,0.892522,NO,203,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.168,-5.086,2.918,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.361275,0.00631514,0.892522 kka2_1:4_L232W,kka2_1:4_232,Kka2,kka2_1:4,P00552,0.89256,NO,232,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.514,-3.426,1.912,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.168804,0.00800103,0.89256 kka2_1:1_V242E,kka2_1:1_242,Kka2,kka2_1:1,P00552,0.892564,NO,242,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-2.687,-2.323,-0.364,,0.75,H,A,0.44,-0.37,4.987,,71.59,HHH,-2.16533,0.520039,0.0102575,0.892564 beta-lactamase_0_T263I,beta-lactamase_0_263,TEM-1,beta-lactamase_0,P62593,0.8926,NO,263,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.0500837,0.0110582,0.8926 kka2_1:2_K175A,kka2_1:2_175,Kka2,kka2_1:2,P00552,0.892727,NO,175,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-2.897,-2.718,-0.179,,0.579,H,A,1.3,0.51,15.629,15.629,71.59,HBH,-1.82333,0.295029,0.00693093,0.892727 kka2_1:2_R145W,kka2_1:2_145,Kka2,kka2_1:2,P00552,0.892727,NO,145,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.804,-3.243,1.439,,0.346,H,A,1.2,1.23,7.961,,63.64,HBP,-1.88033,0.295029,0.00846663,0.892727 beta-lactamase_2500_L218M,beta-lactamase_2500_218,TEM-1,beta-lactamase_2500,P62593,0.892734,NO,218,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.391,-4.267,2.876,,,I,b,0.55,-0.53,9.151,9.151,74.48,OHH,-1.58867,0.361275,0.00618274,0.892734 beta-lactamase_625_R257I,beta-lactamase_625_257,TEM-1,beta-lactamase_625,P62593,0.892764,NO,257,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.213352,0.00756629,0.892764 beta-lactamase_0_N173M,beta-lactamase_0_173,TEM-1,beta-lactamase_0,P62593,0.89278,NO,173,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-2.663,-4.901,2.238,,1.044,T,l,0.61,1.25,1.133,,77.62,OPA,-1.46633,0.0500837,0.0033769,0.89278 kka2_1:4_L70C,kka2_1:4_70,Kka2,kka2_1:4,P00552,0.892787,NO,70,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.017,-4.768,3.751,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.168804,0.00411884,0.892787 beta-lactamase_G216Y,beta-lactamase_216,TEM-1,beta-lactamase,P62593,0.89281,NO,216,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.477,-4.44,2.963,4.91694,0.437,I,A,0.23,-0.58,1.718,,74.48,HOO,-1.68067,0.221079,0.00639568,0.89281 beta-lactamase_G52D,beta-lactamase_52,TEM-1,beta-lactamase,P62593,0.892844,NO,52,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.149,-2.123,0.974,5.12093,0.299,,l,0.77,-0.04,2.103,,64.69,POB,-1.66267,0.221079,0.00340138,0.892844 beta-lactamase_L73S,beta-lactamase_73,TEM-1,beta-lactamase,P62593,0.892852,NO,73,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.507,-3.664,2.157,5.84139,,H,A,1.75,-0.64,2.09,,67.83,HHH,-1.487,0.221079,0.00488983,0.892852 beta-lactamase_2500_I45M,beta-lactamase_2500_45,TEM-1,beta-lactamase_2500,P62593,0.89287,NO,45,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-2.421,-3.375,0.954,,,E,B,0.48,-0.3,3.793,,77.62,HHA,-2.30267,0.361275,0.00452842,0.89287 kka2_1:4_M148T,kka2_1:4_148,Kka2,kka2_1:4,P00552,0.892876,NO,148,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.847,-2.724,0.877,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.168804,0.00982664,0.892876 beta-lactamase_0_M153H,beta-lactamase_0_153,TEM-1,beta-lactamase_0,P62593,0.892881,NO,153,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-3.193,-4.946,1.753,,0.14,T,A,0.55,-0.11,3.826,,77.62,PHO,-2.25767,0.0500837,0.00509109,0.892881 gb1_A249G,gb1_249,gb1,gb1,P06654,0.892908,NO,249,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.739,-3.111,1.372,,,,,,,0.252,,44.87,AHH,-1.67367,0.177985,0.00333585,0.892908 kka2_1:1_S251W,kka2_1:1_251,Kka2,kka2_1:1,P00552,0.892914,NO,251,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.636,-5.587,2.951,,0.712,H,A,0.27,-0.25,1.356,,71.59,APP,-2.09367,0.520039,0.0138916,0.892914 Pab1_L191K,Pab1_191,Pab1,Pab1,P04147,0.892949,NO,191,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.2,-3.495,2.295,,0.204,E,B,,2.24,,,,HHP,-1.20133,0.175299,0.000583797,0.892949 kka2_1:2_L107M,kka2_1:2_107,Kka2,kka2_1:2,P00552,0.892976,NO,107,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.238,-2.856,1.618,,0.197,,B,1.59,-1.1,2.68,,71.59,BHH,-2.143,0.295029,0.00561937,0.892976 kka2_1:8_G99A,kka2_1:8_99,Kka2,kka2_1:8,P00552,0.892984,NO,99,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.596,-2.881,2.285,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.100394,0.00186055,0.892984 kka2_1:8_G99A,kka2_1:8_99,Kka2,kka2_1:8,P00552,0.892984,NO,99,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.596,-2.881,2.285,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.100394,0.00186055,0.892984 beta-lactamase_625_G281M,beta-lactamase_625_281,TEM-1,beta-lactamase_625,P62593,0.892985,NO,281,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.213352,0.0406482,0.892985 beta-lactamase_0_D252F,beta-lactamase_0_252,TEM-1,beta-lactamase_0,P62593,0.892986,NO,252,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.0500837,0.00575769,0.892986 E1_Ubiquitin_I44A,E1_Ubiquitin_44,Uba1,E1_Ubiquitin,P0CG63,0.893015,NO,44,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.432,-2.981,1.549,,,E,B,0.27,-1.17,4.57,,78.74,HHH,-1.25633,0.18783,0.00209731,0.893015 beta-lactamase_0_R202D,beta-lactamase_0_202,TEM-1,beta-lactamase_0,P62593,0.893019,NO,202,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.292,-3.594,2.302,,0.188,H,A,1.2,0.62,7.016,,77.62,PBP,-1.54767,0.0500837,0.00321899,0.893019 beta-lactamase_0_L199T,beta-lactamase_0_199,TEM-1,beta-lactamase_0,P62593,0.893053,NO,199,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-2.942,-2.763,-0.179,,0.832,H,A,0.55,0.42,10.85,10.85,77.62,PHH,-2.32933,0.0500837,0.0048649,0.893053 kka2_1:4_V75W,kka2_1:4_75,Kka2,kka2_1:4,P00552,0.893053,NO,75,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-2.06,-5.286,3.226,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.168804,0.00693733,0.893053 beta-lactamase_2500_F70H,beta-lactamase_2500_70,TEM-1,beta-lactamase_2500,P62593,0.893058,NO,70,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.169,-4.494,3.325,,,H,A,0.58,-1.34,1.918,,63.99,PHB,-0.980667,0.361275,0.00193499,0.893058 kka2_1:2_D180W,kka2_1:2_180,Kka2,kka2_1:2,P00552,0.893067,NO,180,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.416,-5.59,3.174,,1.03,S,a,0.75,1.5,1.27,,71.59,OAO,-2.02933,0.295029,0.00756412,0.893067 beta-lactamase_T262R,beta-lactamase_262,TEM-1,beta-lactamase,P62593,0.893098,NO,262,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.332,-2.32,0.988,5.06002,0.108,E,B,0.3,-0.55,1.423,,67.83,PPO,-2.081,0.221079,0.00853516,0.893098 beta-lactamase_L136V,beta-lactamase_136,TEM-1,beta-lactamase,P62593,0.893114,NO,136,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.232,-1.932,0.7,5.31114,,H,A,2.89,-0.34,1.539,,48.95,HHH,-1.088,0.221079,0.00442304,0.893114 beta-lactamase_0_I261S,beta-lactamase_0_261,TEM-1,beta-lactamase_0,P62593,0.893132,NO,261,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.0500837,0.0123091,0.893132 kka2_1:1_L19M,kka2_1:1_19,Kka2,kka2_1:1,P00552,0.893172,NO,19,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.254,-4.18,2.926,,0.08,T,A,0.55,-0.26,17.165,17.165,65.53,BHH,-2.221,0.520039,0.00620703,0.893172 kka2_1:4_E161W,kka2_1:4_161,Kka2,kka2_1:4,P00552,0.893207,NO,161,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.581,-5.534,3.953,,0.829,G,A,1.52,2.24,1.612,,92.05,AAB,-1.861,0.168804,0.00760103,0.893207 kka2_1:4_H162R,kka2_1:4_162,Kka2,kka2_1:4,P00552,0.893224,NO,162,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-2.319,-1.245,-1.074,,0.071,G,A,0.17,1.01,3.187,,64.39,ABP,-2.02067,0.168804,0.00616145,0.893224 kka2_1:1_T130K,kka2_1:1_130,Kka2,kka2_1:1,P00552,0.893226,NO,130,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.392,-3.096,0.704,,0.561,G,A,0.22,0.77,0.5,,92.05,HPO,-1.62633,0.520039,0.00804204,0.893226 beta-lactamase_156_W288N,beta-lactamase_156_288,TEM-1,beta-lactamase_156,P62593,0.893281,NO,288,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,,,,,,,,,,,,,BHO,,0.111618,,0.893281 beta-lactamase_K190F,beta-lactamase_190,TEM-1,beta-lactamase,P62593,0.893282,NO,190,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.994,-4.396,2.402,5.49163,0.371,H,A,1.82,0.16,29.753,29.753,77.62,BBH,-1.64167,0.221079,0.00574527,0.893282 beta-lactamase_T262V,beta-lactamase_262,TEM-1,beta-lactamase,P62593,0.893282,NO,262,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.332,-3.357,2.025,5.06002,0.108,E,B,0.3,-0.55,1.423,,67.83,PPO,-2.081,0.221079,0.00853516,0.893282 kka2_1:2_T73H,kka2_1:2_73,Kka2,kka2_1:2,P00552,0.893287,NO,73,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.51,-3.503,0.993,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.295029,0.00628605,0.893287 beta-lactamase_0_G243M,beta-lactamase_0_243,TEM-1,beta-lactamase_0,P62593,0.893298,NO,243,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.0500837,0.00464034,0.893298 kka2_1:2_Q4Y,kka2_1:2_4,Kka2,kka2_1:2,P00552,0.89332,NO,4,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.361,-4.04,1.679,,,,,,,2.026,,71.59,APA,-1.95533,0.295029,0.00239179,0.89332 Pab1_L186A,Pab1_186,Pab1,Pab1,P04147,0.893351,NO,186,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.783,-2.923,1.14,,,,,,,,,,HHP,-1.56967,0.175299,0.00154968,0.893351 beta-lactamase_0_L135R,beta-lactamase_0_135,TEM-1,beta-lactamase_0,P62593,0.893366,NO,135,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.002,-4.002,3,,0.117,H,A,0.55,-0.58,0.705,,43.71,PHH,-1.03767,0.0500837,0.00244423,0.893366 beta-lactamase_A124V,beta-lactamase_124,TEM-1,beta-lactamase,P62593,0.893372,NO,124,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.181,-2.519,1.338,4.58507,,H,A,0.58,-0.9,2.273,,64.34,HHH,-1.152,0.221079,0.00481399,0.893372 Pab1_G193W,Pab1_193,Pab1,Pab1,P04147,0.893394,NO,193,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.414,-5.28,3.866,,,,,,,,,,POP,-1.55733,0.175299,0.0014922,0.893394 beta-lactamase_I11G,beta-lactamase_11,TEM-1,beta-lactamase,P62593,0.893398,NO,11,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.745,-3.553,1.808,,,,,,,3.135,,66.08,HHO,-1.79467,0.221079,0.00261325,0.893398 beta-lactamase_0_N168I,beta-lactamase_0_168,TEM-1,beta-lactamase_0,P62593,0.893447,NO,168,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-1.029,-3.943,2.914,,0.113,G,A,0.61,-0.4,0.881,,44.41,HPA,-1.13233,0.0500837,0.00288667,0.893447 beta-lactamase_0_Q276H,beta-lactamase_0_276,TEM-1,beta-lactamase_0,P62593,0.893478,NO,276,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.0500837,0.0191712,0.893478 kka2_1:1_D250Q,kka2_1:1_250,Kka2,kka2_1:1,P00552,0.89352,NO,250,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.015,-2.867,1.852,,0.274,.,b,0.75,-0.46,4.177,,51.89,OAP,-1.83933,0.520039,0.0177103,0.89352 kka2_1:2_A129G,kka2_1:2_129,Kka2,kka2_1:2,P00552,0.893524,NO,129,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.656,-2.673,1.017,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.295029,0.00726862,0.893524 beta-lactamase_625_E102C,beta-lactamase_625_102,TEM-1,beta-lactamase_625,P62593,0.893528,NO,102,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.118,-5.064,2.946,,0.722,S,B,1.04,1.82,1.336,,73.08,HAH,-1.581,0.213352,0.00486633,0.893528 Pab1_G193V,Pab1_193,Pab1,Pab1,P04147,0.893548,NO,193,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.414,-3.699,2.285,,,,,,,,,,POP,-1.55733,0.175299,0.0014922,0.893548 kka2_1:4_T72P,kka2_1:4_72,Kka2,kka2_1:4,P00552,0.893565,NO,72,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.38,-4.008,1.628,,0.784,H,A,0.82,0.29,6.463,,65.53,HPP,-2.238,0.168804,0.00750756,0.893565 beta-lactamase_39_T158N,beta-lactamase_39_158,TEM-1,beta-lactamase_39,P62593,0.89361,NO,158,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.116,-3.488,2.372,,0.036,,B,0.22,-0.85,2.755,,69.58,HPB,-1.269,0.0495842,0.00341825,0.89361 beta-lactamase_0_N274S,beta-lactamase_0_274,TEM-1,beta-lactamase_0,P62593,0.893611,NO,274,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.0500837,0.0110418,0.893611 beta-lactamase_R7W,beta-lactamase_7,TEM-1,beta-lactamase,P62593,0.893632,NO,7,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.683,-5.012,3.329,,,,,,,2.44,,67.13,HBH,-1.96267,0.221079,0.00211375,0.893632 beta-lactamase_156_W288Q,beta-lactamase_156_288,TEM-1,beta-lactamase_156,P62593,0.893637,NO,288,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,,,,,,,,,,,,,BHO,,0.111618,,0.893637 beta-lactamase_0_K286C,beta-lactamase_0_286,TEM-1,beta-lactamase_0,P62593,0.89368,NO,286,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.0500837,,0.89368 kka2_1:8_T28N,kka2_1:8_28,Kka2,kka2_1:8,P00552,0.893688,NO,28,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.883,-3.817,1.934,,0.353,S,B,0.22,2.02,18.114,18.114,63.64,PPH,-1.74467,0.100394,0.00743084,0.893688 kka2_1:8_T28N,kka2_1:8_28,Kka2,kka2_1:8,P00552,0.893688,NO,28,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.883,-3.817,1.934,,0.353,S,B,0.22,2.02,18.114,18.114,63.64,PPH,-1.74467,0.100394,0.00743084,0.893688 beta-lactamase_2500_H24I,beta-lactamase_2500_24,TEM-1,beta-lactamase_2500,P62593,0.893696,NO,24,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-2.481,-3.874,1.393,,,,,,,0.467,,93.01,OBO,-2.0035,0.361275,0.00238894,0.893696 beta-lactamase_G251P,beta-lactamase_251,TEM-1,beta-lactamase,P62593,0.893776,NO,251,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.907,-4.015,2.108,5.33865,0.506,T,l,0.73,0.17,10.663,,65.38,AOB,-2.06067,0.221079,0.00733416,0.893776 beta-lactamase_625_D36P,beta-lactamase_625_36,TEM-1,beta-lactamase_625,P62593,0.893778,NO,36,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.732,-3.967,1.235,,0.555,H,A,0.75,1.17,2.26,,77.62,AAP,-1.91167,0.213352,0.00476483,0.893778 beta-lactamase_39_V106P,beta-lactamase_39_106,TEM-1,beta-lactamase_39,P62593,0.893793,NO,106,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.218,-4.094,2.876,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.0495842,0.00304168,0.893793 PSD95pdz3_G324C,PSD95pdz3_324,PSD95pdz3,PSD95pdz3,P31016,0.893844,NO,324,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.008,-4.769,3.761,4.98881,,,,,10.4525,,,,HOH,-1.293,0.0758425,0.00103462,0.893844 PSD95pdz3_I388G,PSD95pdz3_388,PSD95pdz3,PSD95pdz3,P31016,0.893875,NO,388,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.63,-3.49,1.86,5.17282,,,,,16.0025,,,,PHH,-1.54967,0.0758425,0.000151216,0.893875 beta-lactamase_2500_E62M,beta-lactamase_2500_62,TEM-1,beta-lactamase_2500,P62593,0.893897,NO,62,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.193,-4.77,3.577,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.361275,0.00264802,0.893897 beta-lactamase_M209L,beta-lactamase_209,TEM-1,beta-lactamase,P62593,0.893903,NO,209,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.442,-1.689,0.247,5.44502,,H,A,1.75,-0.97,1.402,,64.69,HHA,-1.52633,0.221079,0.00625021,0.893903 beta-lactamase_2500_K32Y,beta-lactamase_2500_32,TEM-1,beta-lactamase_2500,P62593,0.893923,NO,32,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.984,-4.317,2.333,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.361275,0.00401283,0.893923 kka2_1:4_S54N,kka2_1:4_54,Kka2,kka2_1:4,P00552,0.89394,NO,54,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.471,-3.168,0.697,,0.408,S,b,0.27,1.01,17.332,17.332,71.59,HPO,-2.259,0.168804,0.00782867,0.89394 Pab1_L191W,Pab1_191,Pab1,Pab1,P04147,0.893949,NO,191,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.2,-4.911,3.711,,0.204,E,B,,2.24,,,,HHP,-1.20133,0.175299,0.000583797,0.893949 kka2_1:8_G55A,kka2_1:8_55,Kka2,kka2_1:8,P00552,0.893957,NO,55,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.625,-2.457,0.832,,0.517,S,b,0.29,1.19,8.881,,63.64,POH,-2.05967,0.100394,0.00667877,0.893957 kka2_1:8_G55A,kka2_1:8_55,Kka2,kka2_1:8,P00552,0.893957,NO,55,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.625,-2.457,0.832,,0.517,S,b,0.29,1.19,8.881,,63.64,POH,-2.05967,0.100394,0.00667877,0.893957 beta-lactamase_L73C,beta-lactamase_73,TEM-1,beta-lactamase,P62593,0.893961,NO,73,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.507,-4.861,3.354,5.84139,,H,A,1.75,-0.64,2.09,,67.83,HHH,-1.487,0.221079,0.00488983,0.893961 beta-lactamase_V106S,beta-lactamase_106,TEM-1,beta-lactamase,P62593,0.893971,NO,106,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.218,-3.705,2.487,5.23115,0.258,T,A,0.96,0.24,1.188,,72.73,OHP,-1.04933,0.221079,0.00304168,0.893971 kka2_1:8_A255I,kka2_1:8_255,Kka2,kka2_1:8,P00552,0.894006,NO,255,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.715,-4.011,2.296,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.100394,0.0126809,0.894006 kka2_1:8_A255I,kka2_1:8_255,Kka2,kka2_1:8,P00552,0.894006,NO,255,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.715,-4.011,2.296,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.100394,0.0126809,0.894006 beta-lactamase_0_D33E,beta-lactamase_0_33,TEM-1,beta-lactamase_0,P62593,0.894016,NO,33,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.321,-2.159,-0.162,,0.366,H,A,0.75,0.33,12.514,12.514,77.62,BAH,-2.12133,0.0500837,0.00435556,0.894016 kka2_1:8_L232H,kka2_1:8_232,Kka2,kka2_1:8,P00552,0.894052,NO,232,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.514,-3.411,1.897,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.100394,0.00800103,0.894052 kka2_1:8_L232H,kka2_1:8_232,Kka2,kka2_1:8,P00552,0.894052,NO,232,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.514,-3.411,1.897,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.100394,0.00800103,0.894052 kka2_1:8_P194V,kka2_1:8_194,Kka2,kka2_1:8,P00552,0.894052,NO,194,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.846,-3.62,2.774,,0.308,G,A,0.52,-1.19,4.861,,53.03,HOP,-0.888333,0.100394,0.00314194,0.894052 kka2_1:8_P194V,kka2_1:8_194,Kka2,kka2_1:8,P00552,0.894052,NO,194,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.846,-3.62,2.774,,0.308,G,A,0.52,-1.19,4.861,,53.03,HOP,-0.888333,0.100394,0.00314194,0.894052 beta-lactamase_A40C,beta-lactamase_40,TEM-1,beta-lactamase,P62593,0.894117,NO,40,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.402,-4.779,3.377,4.9697,0.155,S,B,1.2,0.21,1.714,,73.78,OHB,-1.40267,0.221079,0.00490026,0.894117 beta-lactamase_I206N,beta-lactamase_206,TEM-1,beta-lactamase,P62593,0.894117,NO,206,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-2.429,-3.933,1.504,5.3727,0.173,H,A,1,-0.34,2.061,,77.62,HHA,-1.805,0.221079,0.00528934,0.894117 beta-lactamase_L197I,beta-lactamase_197,TEM-1,beta-lactamase,P62593,0.894117,NO,197,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.853,-2.968,2.115,5.19172,0.007,S,B,1.3,0.33,1.756,,60.14,HHP,-1.833,0.221079,0.00144602,0.894117 beta-lactamase_L55T,beta-lactamase_55,TEM-1,beta-lactamase,P62593,0.894117,NO,55,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.86,-3.617,1.757,,0.372,E,A,1.07,-0.36,1.423,,63.99,HHA,-2.247,0.221079,0.00403741,0.894117 beta-lactamase_0_M270Y,beta-lactamase_0_270,TEM-1,beta-lactamase_0,P62593,0.894151,NO,270,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.0500837,0.00767762,0.894151 beta-lactamase_0_L192A,beta-lactamase_0_192,TEM-1,beta-lactamase_0,P62593,0.894172,NO,192,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.254,-2.317,1.063,,0.095,H,A,0.55,0.35,1.756,,60.14,HHP,-1.41833,0.0500837,0.00558728,0.894172 kka2_1:2_G43F,kka2_1:2_43,Kka2,kka2_1:2,P00552,0.894189,NO,43,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.587,-4.379,2.792,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.295029,0.0071925,0.894189 beta-lactamase_0_L136Y,beta-lactamase_0_136,TEM-1,beta-lactamase_0,P62593,0.894191,NO,136,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.232,-4.051,2.819,,,H,A,0.55,-0.34,0.648,,48.95,HHH,-1.088,0.0500837,0.00442304,0.894191 kka2_1:1_A168K,kka2_1:1_168,Kka2,kka2_1:1,P00552,0.894194,NO,168,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.989,-2.846,0.857,,0.67,H,A,0.46,0.15,25.546,25.546,64.39,OHA,-2.12933,0.520039,0.00806773,0.894194 kka2_1:4_G88T,kka2_1:4_88,Kka2,kka2_1:4,P00552,0.894197,NO,88,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.689,-3.065,1.376,,0.54,S,l,0.29,1.51,7.899,,65.53,HOB,-1.718,0.168804,0.00685559,0.894197 beta-lactamase_0_M184L,beta-lactamase_0_184,TEM-1,beta-lactamase_0,P62593,0.894235,NO,184,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.593,-2.806,1.213,,,H,A,0.55,-0.87,13.292,13.292,62.94,HHH,-1.41,0.0500837,0.00356019,0.894235 beta-lactamase_T107V,beta-lactamase_107,TEM-1,beta-lactamase,P62593,0.894252,NO,107,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.117,-3.226,2.109,5.23432,,G,A,2.12,-0.06,3.676,,67.83,HPA,-1.265,0.221079,0.00239347,0.894252 beta-lactamase_0_L160G,beta-lactamase_0_160,TEM-1,beta-lactamase_0,P62593,0.894256,NO,160,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.977,-3.824,2.847,,0.022,,B,0.55,-0.6,0.68,,44.41,BHA,-0.936,0.0500837,0.00193775,0.894256 kka2_1:4_P45T,kka2_1:4_45,Kka2,kka2_1:4,P00552,0.894279,NO,45,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.774,-2.639,0.865,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.168804,0.00590481,0.894279 beta-lactamase_0_L47M,beta-lactamase_0_47,TEM-1,beta-lactamase_0,P62593,0.894308,NO,47,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.876,-2.629,0.753,,0.007,E,B,0.55,0.2,1.024,,67.83,AHA,-1.639,0.0500837,0.00439844,0.894308 beta-lactamase_0_G240P,beta-lactamase_0_240,TEM-1,beta-lactamase_0,P62593,0.894342,NO,240,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.0500837,0.00591201,0.894342 kka2_1:1_A248L,kka2_1:1_248,Kka2,kka2_1:1,P00552,0.894342,NO,248,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.124,-3.034,0.91,,0.825,S,b,0.46,0.46,24.72,24.72,92.05,HHO,-2.15,0.520039,0.0125484,0.894342 PSD95pdz3_R318V,PSD95pdz3_318,PSD95pdz3,PSD95pdz3,P31016,0.894411,NO,318,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.582,-3.435,1.853,4.94876,,,,,17.5609,,,,BBO,-1.40567,0.0758425,0.00110471,0.894411 kka2_1:2_G233V,kka2_1:2_233,Kka2,kka2_1:2,P00552,0.894455,NO,233,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.748,-3.827,3.079,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.295029,0.00232366,0.894455 WW_domain_D201A,WW_domain_201,Yap65,WW_domain,P46937,0.894487,NO,201,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.369,-3.024,1.655,4.90312,,,,,,20.806,20.806,70.04,PAO,-1.456,0.153962,0.00248402,0.894487 beta-lactamase_0_N134H,beta-lactamase_0_134,TEM-1,beta-lactamase_0,P62593,0.894511,NO,134,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-0.879,-4.073,3.194,,0.138,H,A,0.61,-0.6,3.776,,53.15,HPH,-1.02233,0.0500837,0.000644786,0.894511 beta-lactamase_0_D177Q,beta-lactamase_0_177,TEM-1,beta-lactamase_0,P62593,0.894514,NO,177,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.967,-3.799,2.832,,0.006,T,L,0.75,-1.02,3.536,,64.69,BAP,-0.873667,0.0500837,0.000864022,0.894514 beta-lactamase_G216H,beta-lactamase_216,TEM-1,beta-lactamase,P62593,0.89456,NO,216,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.477,-4.598,3.121,4.91694,0.437,I,A,0.23,-0.58,1.718,,74.48,HOO,-1.68067,0.221079,0.00639568,0.89456 beta-lactamase_2500_W163A,beta-lactamase_2500_163,TEM-1,beta-lactamase_2500,P62593,0.894572,NO,163,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-1.843,-3.41,1.567,,0.467,,B,0.47,-0.5,32.624,32.624,63.99,BHA,-1.269,0.361275,0.00418955,0.894572 beta-lactamase_2500_V106Q,beta-lactamase_2500_106,TEM-1,beta-lactamase_2500,P62593,0.894574,NO,106,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.218,-4.248,3.03,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.361275,0.00304168,0.894574 beta-lactamase_0_Q203E,beta-lactamase_0_203,TEM-1,beta-lactamase_0,P62593,0.894582,NO,203,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.168,-2.449,0.281,,0.47,H,A,0.64,-0.38,14.541,14.541,65.38,BPP,-1.614,0.0500837,0.00631514,0.894582 beta-lactamase_0_L248A,beta-lactamase_0_248,TEM-1,beta-lactamase_0,P62593,0.894625,NO,248,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.0500837,0.00428493,0.894625 kka2_1:8_P194R,kka2_1:8_194,Kka2,kka2_1:8,P00552,0.894641,NO,194,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.846,-3.983,3.137,,0.308,G,A,0.52,-1.19,4.861,,53.03,HOP,-0.888333,0.100394,0.00314194,0.894641 kka2_1:8_P194R,kka2_1:8_194,Kka2,kka2_1:8,P00552,0.894641,NO,194,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.846,-3.983,3.137,,0.308,G,A,0.52,-1.19,4.861,,53.03,HOP,-0.888333,0.100394,0.00314194,0.894641 beta-lactamase_L28Q,beta-lactamase_28,TEM-1,beta-lactamase,P62593,0.894664,NO,28,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.579,-2.97,1.391,5.42969,0.277,H,A,0.07,-0.16,19.748,19.748,93.01,PHH,-2.11333,0.221079,0.00359321,0.894664 beta-lactamase_N272T,beta-lactamase_272,TEM-1,beta-lactamase,P62593,0.894711,NO,272,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-1.127,-3.348,2.221,5.37826,0.081,H,A,0.09,-0.97,1.468,,63.64,BPB,-1.56333,0.221079,0.00545371,0.894711 beta-lactamase_2500_W163Q,beta-lactamase_2500_163,TEM-1,beta-lactamase_2500,P62593,0.894739,NO,163,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-1.843,-2.929,1.086,,0.467,,B,0.47,-0.5,32.624,32.624,63.99,BHA,-1.269,0.361275,0.00418955,0.894739 beta-lactamase_0_R202H,beta-lactamase_0_202,TEM-1,beta-lactamase_0,P62593,0.894742,NO,202,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.292,-4.365,3.073,,0.188,H,A,1.2,0.62,7.016,,77.62,PBP,-1.54767,0.0500837,0.00321899,0.894742 PSD95pdz3_G345C,PSD95pdz3_345,PSD95pdz3,PSD95pdz3,P31016,0.894754,NO,345,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.008,-4.769,3.761,4.32868,,,,,13.165,,,,OOO,-1.084,0.0758425,0.000771806,0.894754 gb1_L231F,gb1_231,gb1,gb1,P06654,0.894776,NO,231,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.603,-3.035,1.432,,,,,,,0.219,,11.83,BHH,-1.82633,0.177985,0.00322797,0.894776 gb1_L233P,gb1_233,gb1,gb1,P06654,0.894776,NO,233,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-2.678,-3.702,1.024,,,,,,,0.822,,45.54,HHP,-2.30267,0.177985,0.00266958,0.894776 kka2_1:2_L60P,kka2_1:2_60,Kka2,kka2_1:2,P00552,0.894777,NO,60,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.997,-4.194,3.197,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.295029,0.00262176,0.894777 kka2_1:4_G55V,kka2_1:4_55,Kka2,kka2_1:4,P00552,0.894803,NO,55,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.625,-3.678,2.053,,0.517,S,b,0.75,1.19,15.753,15.753,63.64,POH,-2.05967,0.168804,0.00667877,0.894803 beta-lactamase_39_R59V,beta-lactamase_39_59,TEM-1,beta-lactamase_39,P62593,0.894817,NO,59,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.345,-3.76,2.415,,0.329,S,L,1.2,-0.09,1.806,,73.08,HBO,-2.24267,0.0495842,0.00318082,0.894817 beta-lactamase_E56M,beta-lactamase_56,TEM-1,beta-lactamase,P62593,0.894833,NO,56,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.043,-4.624,2.581,5.65281,0.198,E,B,0.52,0.31,2.022,,72.73,HAP,-1.94033,0.221079,0.00238534,0.894833 beta-lactamase_L192C,beta-lactamase_192,TEM-1,beta-lactamase,P62593,0.894833,NO,192,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.254,-4.743,3.489,5.68899,0.095,H,A,1.3,0.35,1.756,,60.14,HHP,-1.41833,0.221079,0.00558728,0.894833 beta-lactamase_G263S,beta-lactamase_263,TEM-1,beta-lactamase,P62593,0.894935,NO,263,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-2.031,-3.36,1.329,5.09799,0.517,S,l,0.77,0.31,16.425,16.425,77.62,POP,-1.78267,0.221079,0.0110582,0.894935 Pab1_A179R,Pab1_179,Pab1,Pab1,P04147,0.89494,NO,179,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.013,-3.525,2.512,,0.078,H,A,0.61,0.5,,,,HHB,-1.51233,0.175299,0.000291703,0.89494 beta-lactamase_0_D212G,beta-lactamase_0_212,TEM-1,beta-lactamase_0,P62593,0.894948,NO,212,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.624,-2.198,0.574,,0.037,,b,0.75,-0.58,3.34,,74.48,HAB,-1.77667,0.0500837,0.00644302,0.894948 WW_domain_T182M,WW_domain_182,Yap65,WW_domain,P46937,0.894964,NO,182,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.149,-4.257,3.108,6.20597,,,,,,,,,BPP,-1.483,0.153962,0.00294574,0.894964 beta-lactamase_E87T,beta-lactamase_87,TEM-1,beta-lactamase,P62593,0.894965,NO,87,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.421,-2.787,1.366,5.41929,0.048,,B,0.52,0.92,1.754,,64.69,PAP,-1.969,0.221079,0.00337888,0.894965 beta-lactamase_A235S,beta-lactamase_235,TEM-1,beta-lactamase,P62593,0.89497,NO,235,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.266,-2.058,0.792,4.83024,0.32,E,B,0.52,-0.86,1.344,,50,OHO,-0.89,0.221079,0.00493474,0.89497 beta-lactamase_2500_D99V,beta-lactamase_2500_99,TEM-1,beta-lactamase_2500,P62593,0.895001,NO,99,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.191,-3.648,2.457,,0.402,G,A,0.75,0.36,1.318,,64.69,PAH,-1.794,0.361275,0.00305446,0.895001 kka2_1:8_D208A,kka2_1:8_208,Kka2,kka2_1:8,P00552,0.895003,NO,208,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.708,-3.331,2.623,,0.36,,l,0.29,-1.01,,,,HAO,-0.929667,0.100394,0.00212588,0.895003 kka2_1:8_D208A,kka2_1:8_208,Kka2,kka2_1:8,P00552,0.895003,NO,208,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.708,-3.331,2.623,,0.36,,l,0.29,-1.01,,,,HAO,-0.929667,0.100394,0.00212588,0.895003 beta-lactamase_D161N,beta-lactamase_161,TEM-1,beta-lactamase,P62593,0.89502,NO,161,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.891,-3.293,2.402,5.12208,0.341,,A,0.23,-0.52,1.602,,61.19,HAB,-0.961333,0.221079,0.000897697,0.89502 beta-lactamase_H110A,beta-lactamase_110,TEM-1,beta-lactamase,P62593,0.89502,NO,110,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-1.706,-3.353,1.647,5.52635,0.341,G,a,0.35,1.08,31.31,31.31,64.69,BBH,-1.73333,0.221079,0.00441499,0.89502 beta-lactamase_0_H287Q,beta-lactamase_0_287,TEM-1,beta-lactamase_0,P62593,0.895078,NO,287,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,,,,,,,,,,,,,BBH,-1.111,0.0500837,,0.895078 beta-lactamase_T147K,beta-lactamase_147,TEM-1,beta-lactamase,P62593,0.895092,NO,147,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.149,-3.536,2.387,5.37474,0.281,H,A,0.8,-0.68,2.838,,64.34,HPH,-1.456,0.221079,0.00226017,0.895092 Pab1_L153K,Pab1_153,Pab1,Pab1,P04147,0.895127,NO,153,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.039,-3.499,2.46,,0.46,E,A,,-0.95,,,,HHP,-1.17667,0.175299,0.000321212,0.895127 beta-lactamase_T126L,beta-lactamase_126,TEM-1,beta-lactamase,P62593,0.895154,NO,126,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.122,-3.373,2.251,4.82694,0.05,H,A,0.3,-0.05,1.14,,44.41,HPH,-1.60467,0.221079,0.00244552,0.895154 Ubiquitin_A28I,Ubiquitin_28,Uba1,Ubiquitin,P0CG48,0.895161,NO,28,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.895,-3.05,1.155,4.73736,0.369,H,A,,-0.11,,,,BHB,-1.47667,0.205827,0.000842053,0.895161 Ubiquitin_D24Y,Ubiquitin_24,Uba1,Ubiquitin,P0CG48,0.895161,NO,24,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,,,,,,,,,,,,,HAP,,0.205827,0.0066591,0.895161 Ubiquitin_D32G,Ubiquitin_32,Uba1,Ubiquitin,P0CG48,0.895161,NO,32,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.451,-3.281,1.83,4.96502,0.835,H,A,,1.4,,,,PAB,-1.47067,0.205827,0.000758819,0.895161 Ubiquitin_D32H,Ubiquitin_32,Uba1,Ubiquitin,P0CG48,0.895161,NO,32,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.451,-4.399,2.948,4.96502,0.835,H,A,,1.4,,,,PAB,-1.47067,0.205827,0.000758819,0.895161 Ubiquitin_D32T,Ubiquitin_32,Uba1,Ubiquitin,P0CG48,0.895161,NO,32,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.451,-2.678,1.227,4.96502,0.835,H,A,,1.4,,,,PAB,-1.47067,0.205827,0.000758819,0.895161 Ubiquitin_G10N,Ubiquitin_10,Uba1,Ubiquitin,P0CG48,0.895161,NO,10,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.396,-3.618,2.222,5.29806,0.115,S,l,,0.2,,,,POB,-1.38633,0.205827,0.000748953,0.895161 Ubiquitin_I3T,Ubiquitin_3,Uba1,Ubiquitin,P0CG48,0.895161,NO,3,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.402,-2.569,1.167,4.80819,,E,B,,-0.78,,,,PHH,-1.54533,0.205827,0.000836911,0.895161 Ubiquitin_K11C,Ubiquitin_11,Uba1,Ubiquitin,P0CG48,0.895161,NO,11,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.354,-5.105,3.751,5.16813,0.401,,B,2.81,0.84,0.335,,25.84,OBP,-1.346,0.205827,0.000535553,0.895161 Ubiquitin_K27G,Ubiquitin_27,Uba1,Ubiquitin,P0CG48,0.895161,NO,27,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.064,-2.309,1.245,4.77438,0.086,H,A,2.89,-0.74,2.662,,27.01,HBH,-1.42667,0.205827,0.000767556,0.895161 Ubiquitin_Q31I,Ubiquitin_31,Uba1,Ubiquitin,P0CG48,0.895161,NO,31,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-1.678,-4.115,2.437,4.5004,0.464,H,A,,0.68,,,,HPA,-1.44467,0.205827,0.000724141,0.895161 Ubiquitin_T22F,Ubiquitin_22,Uba1,Ubiquitin,P0CG48,0.895161,NO,22,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.344,-4.104,2.76,4.54389,0.237,B,B,,-0.75,,,,APH,-1.28733,0.205827,0.000535592,0.895161 Ubiquitin_T66H,Ubiquitin_66,Uba1,Ubiquitin,P0CG48,0.895161,NO,66,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.58,-3.267,1.687,5.02702,0.46,E,B,0.8,-0.81,28.36,28.36,39.71,PPH,-1.51667,0.205827,0.000598414,0.895161 Ubiquitin_T66L,Ubiquitin_66,Uba1,Ubiquitin,P0CG48,0.895161,NO,66,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.58,-3.267,1.687,5.02702,0.46,E,B,0.8,-0.81,28.36,28.36,39.71,PPH,-1.51667,0.205827,0.000598414,0.895161 Ubiquitin_T9G,Ubiquitin_9,Uba1,Ubiquitin,P0CG48,0.895161,NO,9,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.409,-3.353,1.944,5.24336,0.777,T,A,2.12,-0.12,2.705,,29.93,HPO,-1.50933,0.205827,0.000630716,0.895161 Ubiquitin_V5T,Ubiquitin_5,Uba1,Ubiquitin,P0CG48,0.895161,NO,5,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.576,-3.36,1.784,4.75677,,E,B,,-0.82,,,,HHB,-1.401,0.205827,0.000796998,0.895161 Ubiquitin_Y59S,Ubiquitin_59,Uba1,Ubiquitin,P0CG48,0.895161,NO,59,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-1.307,-2.753,1.446,5.05599,0.072,G,A,0.43,-0.74,2.566,,24.53,AHP,-1.568,0.205827,0.000775084,0.895161 beta-lactamase_R238E,beta-lactamase_238,TEM-1,beta-lactamase,P62593,0.895165,NO,238,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.002,-3.465,1.463,5.87663,0.564,T,L,0.45,1.09,4.195,,72.73,ABO,-1.62633,0.221079,0.00743256,0.895165 Pab1_G169C,Pab1_169,Pab1,Pab1,P04147,0.895183,NO,169,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.809,-4.904,4.095,,,E,b,0.35,0.03,,,,HOH,-1.11567,0.175299,0.000302434,0.895183 beta-lactamase_39_S233H,beta-lactamase_39_233,TEM-1,beta-lactamase_39,P62593,0.895197,NO,233,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.886,-4.67,2.784,,0.016,E,B,0.27,-1.01,5.361,,77.62,BPO,-1.17267,0.0495842,0.00311415,0.895197 beta-lactamase_A276L,beta-lactamase_276,TEM-1,beta-lactamase,P62593,0.895256,NO,276,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.144,-3.183,2.039,5.1387,0.117,H,A,0.52,-0.84,1.283,,44.06,HHA,-1.47,0.221079,0.0191712,0.895256 beta-lactamase_0_M209F,beta-lactamase_0_209,TEM-1,beta-lactamase_0,P62593,0.89526,NO,209,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.442,-2.51,1.068,,,H,A,0.55,-0.97,3.876,,64.69,HHA,-1.52633,0.0500837,0.00625021,0.89526 kka2_1:8_R239G,kka2_1:8_239,Kka2,kka2_1:8,P00552,0.895342,NO,239,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.949,-2.877,-0.072,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.100394,0.00835326,0.895342 kka2_1:8_R239G,kka2_1:8_239,Kka2,kka2_1:8,P00552,0.895342,NO,239,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.949,-2.877,-0.072,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.100394,0.00835326,0.895342 kka2_1:2_E231K,kka2_1:2_231,Kka2,kka2_1:2,P00552,0.895359,NO,231,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.002,-3.423,1.421,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.295029,0.00732383,0.895359 beta-lactamase_2500_Q276G,beta-lactamase_2500_276,TEM-1,beta-lactamase_2500,P62593,0.895407,NO,276,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.361275,0.0191712,0.895407 Pab1_A158T,Pab1_158,Pab1,Pab1,P04147,0.895414,NO,158,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.154,-3.067,1.913,,,,,,,1.197,,56.33,HHP,-1.40733,0.175299,0.000649733,0.895414 beta-lactamase_0_G249S,beta-lactamase_0_249,TEM-1,beta-lactamase_0,P62593,0.895415,NO,249,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.0500837,0.00220169,0.895415 kka2_1:8_E231M,kka2_1:8_231,Kka2,kka2_1:8,P00552,0.895423,NO,231,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.002,-4.813,2.811,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.100394,0.00732383,0.895423 kka2_1:8_E231M,kka2_1:8_231,Kka2,kka2_1:8,P00552,0.895423,NO,231,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.002,-4.813,2.811,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.100394,0.00732383,0.895423 beta-lactamase_0_V101R,beta-lactamase_0_101,TEM-1,beta-lactamase_0,P62593,0.895461,NO,101,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.295,-4.134,2.839,,0.342,,B,0.44,0,1.61,,73.08,HHA,-1.54367,0.0500837,0.00374492,0.895461 beta-lactamase_2500_P165L,beta-lactamase_2500_165,TEM-1,beta-lactamase_2500,P62593,0.895472,NO,165,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.373,-3.388,2.015,,0.203,T,A,0.52,-0.31,0.414,,73.78,AOA,-1.359,0.361275,0.00549538,0.895472 kka2_1:2_D82G,kka2_1:2_82,Kka2,kka2_1:2,P00552,0.895473,NO,82,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.946,-2.495,0.549,,0.341,E,b,0.75,0.52,11.923,11.923,63.64,HAH,-1.98,0.295029,0.00637516,0.895473 kka2_1:8_R147W,kka2_1:8_147,Kka2,kka2_1:8,P00552,0.895478,NO,147,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.123,-5.411,4.288,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.100394,0.00549168,0.895478 kka2_1:8_R147W,kka2_1:8_147,Kka2,kka2_1:8,P00552,0.895478,NO,147,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.123,-5.411,4.288,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.100394,0.00549168,0.895478 beta-lactamase_T187G,beta-lactamase_187,TEM-1,beta-lactamase,P62593,0.895484,NO,187,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.401,-3.394,1.993,5.11453,0.007,H,A,0.3,-1.19,1.751,,67.48,PPH,-1.69633,0.221079,0.00491782,0.895484 beta-lactamase_2500_A211Y,beta-lactamase_2500_211,TEM-1,beta-lactamase_2500,P62593,0.895518,NO,211,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.896,-4.344,2.448,,0.369,T,A,0.46,-0.69,2.061,,77.62,AHA,-1.94633,0.361275,0.00648183,0.895518 beta-lactamase_E62V,beta-lactamase_62,TEM-1,beta-lactamase,P62593,0.895518,NO,62,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.193,-3.636,2.443,5.93066,0.342,S,B,1.52,-0.3,3.139,,73.08,AAB,-1.417,0.221079,0.00264802,0.895518 beta-lactamase_0_G154S,beta-lactamase_0_154,TEM-1,beta-lactamase_0,P62593,0.895558,NO,154,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.823,-3.197,2.374,,0.54,T,l,0.29,-0.56,3.629,,64.69,HOA,-1.635,0.0500837,0.00180205,0.895558 kka2_1:1_V46S,kka2_1:1_46,Kka2,kka2_1:1,P00552,0.895586,NO,46,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-2.62,-2.564,-0.056,,0.192,.,B,0.44,-1.12,20.149,20.149,92.05,OHH,-1.88633,0.520039,0.00631301,0.895586 beta-lactamase_0_M115S,beta-lactamase_0_115,TEM-1,beta-lactamase_0,P62593,0.895631,NO,115,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.389,-3.501,2.112,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.0500837,0.0034337,0.895631 kka2_1:4_L123M,kka2_1:4_123,Kka2,kka2_1:4,P00552,0.895767,NO,123,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.888,-2.619,1.731,,0.007,H,A,0.55,-0.4,1.447,,48.86,BHB,-1.301,0.168804,0.00325188,0.895767 kka2_1:8_L184M,kka2_1:8_184,Kka2,kka2_1:8,P00552,0.895794,NO,184,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.496,-3.37,1.874,,0.489,E,B,0.55,-0.06,4.495,,63.26,AHH,-1.24833,0.100394,0.00518742,0.895794 kka2_1:8_L184M,kka2_1:8_184,Kka2,kka2_1:8,P00552,0.895794,NO,184,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.496,-3.37,1.874,,0.489,E,B,0.55,-0.06,4.495,,63.26,AHH,-1.24833,0.100394,0.00518742,0.895794 PSD95pdz3_A390P,PSD95pdz3_390,PSD95pdz3,PSD95pdz3,P31016,0.895807,NO,390,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.307,-3.336,2.029,5.03823,,,,,12.46,,,,HHP,-1.54467,0.0758425,0.00104603,0.895807 beta-lactamase_0_V260W,beta-lactamase_0_260,TEM-1,beta-lactamase_0,P62593,0.895809,NO,260,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.0500837,0.00471757,0.895809 beta-lactamase_0_H287K,beta-lactamase_0_287,TEM-1,beta-lactamase_0,P62593,0.89581,NO,287,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,,,,,,,,,,,,,BBH,-1.111,0.0500837,,0.89581 kka2_1:2_A79I,kka2_1:2_79,Kka2,kka2_1:2,P00552,0.895816,NO,79,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.368,-3.11,0.742,,0.563,.,B,0.46,-0.43,0.475,,71.59,HHH,-1.752,0.295029,0.00664821,0.895816 beta-lactamase_0_D231R,beta-lactamase_0_231,TEM-1,beta-lactamase_0,P62593,0.895836,NO,231,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.816,-3.896,3.08,,,E,B,0.75,-1.06,4.975,,65.38,HAB,-0.994,0.0500837,0.00107395,0.895836 beta-lactamase_625_D212K,beta-lactamase_625_212,TEM-1,beta-lactamase_625,P62593,0.89584,NO,212,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.624,-3.581,1.957,,0.037,,b,0.75,-0.58,1.516,,74.48,HAB,-1.77667,0.213352,0.00644302,0.89584 beta-lactamase_0_L137K,beta-lactamase_0_137,TEM-1,beta-lactamase_0,P62593,0.895853,NO,137,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.03,-3.749,2.719,,,H,A,0.55,-0.38,0.328,,42.31,HHP,-1.58933,0.0500837,0.00278599,0.895853 kka2_1:4_Y22L,kka2_1:4_22,Kka2,kka2_1:4,P00552,0.895922,NO,22,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-1.583,-3.408,1.825,,0.122,.,B,0.21,-0.8,1.838,,65.53,OHA,-1.80333,0.168804,0.00598977,0.895922 PSD95pdz3_G322M,PSD95pdz3_322,PSD95pdz3,PSD95pdz3,P31016,0.895975,NO,322,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.008,-4.612,3.604,5.24791,,,,,16.3275,,,,POH,-1.24867,0.0758425,0.00105821,0.895975 beta-lactamase_0_T112Q,beta-lactamase_0_112,TEM-1,beta-lactamase_0,P62593,0.895991,NO,112,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.186,-3.981,1.795,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.0500837,0.00531334,0.895991 beta-lactamase_A211W,beta-lactamase_211,TEM-1,beta-lactamase,P62593,0.895997,NO,211,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.896,-5.506,3.61,5.54662,0.369,T,A,0.52,-0.69,2.061,,77.62,AHA,-1.94633,0.221079,0.00648183,0.895997 beta-lactamase_E277Y,beta-lactamase_277,TEM-1,beta-lactamase,P62593,0.895997,NO,277,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.869,-4.426,2.557,5.51786,0.545,H,A,0.52,-0.01,2.022,,77.62,HAH,-1.45367,0.221079,0.0169305,0.895997 beta-lactamase_H110W,beta-lactamase_110,TEM-1,beta-lactamase,P62593,0.895997,NO,110,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-1.706,-5.185,3.479,5.52635,0.341,G,a,0.35,1.08,31.31,31.31,64.69,BBH,-1.73333,0.221079,0.00441499,0.895997 beta-lactamase_Q4W,beta-lactamase_4,TEM-1,beta-lactamase,P62593,0.895997,NO,4,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,,-5.297,2.733,,,,,,,,,,HPB,,0.221079,0.00316562,0.895997 beta-lactamase_S281D,beta-lactamase_281,TEM-1,beta-lactamase,P62593,0.895997,NO,281,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.247,-3.785,1.538,4.73591,0.128,H,A,0.25,-0.26,2.144,,77.62,HPH,-1.847,0.221079,0.0406482,0.895997 beta-lactamase_X287K,beta-lactamase_287,TEM-1,beta-lactamase,P62593,0.895997,NO,287,X,K,XK,Stop,PositiveCharge,5.71,9.74,4.03,,132.5,146,13,141.9,168.6,26.7,,,,,,,,,,,,,HXO,-1.111,0.221079,,0.895997 kka2_1:8_E182G,kka2_1:8_182,Kka2,kka2_1:8,P00552,0.895997,NO,182,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.516,-2.588,1.072,,0.326,,B,1.52,0.75,2.568,,65.53,OAA,-1.806,0.100394,0.00641548,0.895997 kka2_1:8_E182G,kka2_1:8_182,Kka2,kka2_1:8,P00552,0.895997,NO,182,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.516,-2.588,1.072,,0.326,,B,1.52,0.75,2.568,,65.53,OAA,-1.806,0.100394,0.00641548,0.895997 beta-lactamase_625_V214W,beta-lactamase_625_214,TEM-1,beta-lactamase_625,P62593,0.896018,NO,214,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.299,-5.33,4.031,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.213352,0.00628442,0.896018 kka2_1:2_D23I,kka2_1:2_23,Kka2,kka2_1:2,P00552,0.896082,NO,23,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.459,-4.001,1.542,,0.695,E,B,0.75,-0.65,18.207,18.207,65.53,HAH,-1.94033,0.295029,0.007195,0.896082 beta-lactamase_0_T116I,beta-lactamase_0_116,TEM-1,beta-lactamase_0,P62593,0.89609,NO,116,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.28,-3.822,2.542,,0.115,E,B,0.22,-0.12,1.356,,67.48,HPH,-1.39967,0.0500837,0.00336175,0.89609 beta-lactamase_0_N134L,beta-lactamase_0_134,TEM-1,beta-lactamase_0,P62593,0.896107,NO,134,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-0.879,-3.581,2.702,,0.138,H,A,0.61,-0.6,3.776,,53.15,HPH,-1.02233,0.0500837,0.000644786,0.896107 beta-lactamase_0_E119D,beta-lactamase_0_119,TEM-1,beta-lactamase_0,P62593,0.896119,NO,119,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.412,-2.093,0.681,,0.358,H,A,1.04,0.51,3.396,,63.99,BAH,-1.623,0.0500837,0.00386966,0.896119 beta-lactamase_0_D252T,beta-lactamase_0_252,TEM-1,beta-lactamase_0,P62593,0.896159,NO,252,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.0500837,0.00575769,0.896159 kka2_1:4_R89H,kka2_1:4_89,Kka2,kka2_1:4,P00552,0.896165,NO,89,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.548,-2.435,0.887,,0.209,E,B,1.2,1.41,4.412,,64.39,OBA,-1.89867,0.168804,0.00524373,0.896165 PSD95pdz3_Q374I,PSD95pdz3_374,PSD95pdz3,PSD95pdz3,P31016,0.896212,NO,374,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-1.699,-3.692,1.993,5.38825,,,,,17.3289,,,,APH,-1.47,0.0758425,0.000372298,0.896212 beta-lactamase_0_E56L,beta-lactamase_0_56,TEM-1,beta-lactamase_0,P62593,0.896286,NO,56,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.043,-3.398,1.355,,0.198,E,B,1.04,0.31,1.491,,72.73,HAP,-1.94033,0.0500837,0.00238534,0.896286 kka2_1:4_S105G,kka2_1:4_105,Kka2,kka2_1:4,P00552,0.896305,NO,105,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.945,-2.84,0.895,,0.056,S,B,0.77,-1.04,3.442,,65.53,PPB,-2.17033,0.168804,0.00847233,0.896305 beta-lactamase_2500_R202V,beta-lactamase_2500_202,TEM-1,beta-lactamase_2500,P62593,0.896318,NO,202,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.292,-3.679,2.387,,0.188,H,A,1.2,0.62,3.734,,77.62,PBP,-1.54767,0.361275,0.00321899,0.896318 beta-lactamase_0_G85M,beta-lactamase_0_85,TEM-1,beta-lactamase_0,P62593,0.89635,NO,85,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.011,-4.877,3.866,,0.805,T,l,0.29,1.7,2.25,,63.64,HOP,-1.68733,0.0500837,0.00252173,0.89635 beta-lactamase_T186P,beta-lactamase_186,TEM-1,beta-lactamase,P62593,0.896351,NO,186,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.522,-3.945,1.423,5.07364,0.396,H,A,0.3,-0.28,2.144,,77.62,HPP,-1.77633,0.221079,0.00485034,0.896351 beta-lactamase_0_S51T,beta-lactamase_0_51,TEM-1,beta-lactamase_0,P62593,0.896377,NO,51,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.526,-1.846,0.32,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.0500837,0.00504821,0.896377 kka2_1:8_C192M,kka2_1:8_192,Kka2,kka2_1:8,P00552,0.896382,NO,192,C,M,CM,Special,Hydrophobic,5.07,5.74,0.67,196,121,149,28,108.5,162.9,54.4,-1.067,-4.582,3.515,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.100394,0.00485428,0.896382 kka2_1:8_C192M,kka2_1:8_192,Kka2,kka2_1:8,P00552,0.896382,NO,192,C,M,CM,Special,Hydrophobic,5.07,5.74,0.67,196,121,149,28,108.5,162.9,54.4,-1.067,-4.582,3.515,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.100394,0.00485428,0.896382 kka2_1:8_L107K,kka2_1:8_107,Kka2,kka2_1:8,P00552,0.896418,NO,107,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.238,-3.819,2.581,,0.197,.,B,0.55,-1.1,4.478,,71.59,BHH,-2.143,0.100394,0.00561937,0.896418 kka2_1:8_L107K,kka2_1:8_107,Kka2,kka2_1:8,P00552,0.896418,NO,107,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.238,-3.819,2.581,,0.197,.,B,0.55,-1.1,4.478,,71.59,BHH,-2.143,0.100394,0.00561937,0.896418 beta-lactamase_L38S,beta-lactamase_38,TEM-1,beta-lactamase,P62593,0.896476,NO,38,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.343,-2.597,1.254,5.23728,0.088,H,A,1.75,0.2,1.986,,64.34,PHO,-1.78033,0.221079,0.00373244,0.896476 beta-lactamase_0_A200I,beta-lactamase_0_200,TEM-1,beta-lactamase_0,P62593,0.896498,NO,200,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.878,-3.937,2.059,,0.757,H,A,0.46,-0.19,16.368,16.368,77.62,HHP,-2.001,0.0500837,0.0060056,0.896498 kka2_1:8_G30S,kka2_1:8_30,Kka2,kka2_1:8,P00552,0.89656,NO,30,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.596,-3.189,2.593,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.100394,0.00159208,0.89656 kka2_1:8_G30S,kka2_1:8_30,Kka2,kka2_1:8,P00552,0.89656,NO,30,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.596,-3.189,2.593,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.100394,0.00159208,0.89656 kka2_1:8_P132Q,kka2_1:8_132,Kka2,kka2_1:8,P00552,0.89656,NO,132,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.775,-3.926,3.151,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.100394,0.0018489,0.89656 kka2_1:8_P132Q,kka2_1:8_132,Kka2,kka2_1:8,P00552,0.89656,NO,132,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.775,-3.926,3.151,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.100394,0.0018489,0.89656 kka2_1:2_D183R,kka2_1:2_183,Kka2,kka2_1:2,P00552,0.896561,NO,183,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.204,-2.951,1.747,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.295029,0.00426304,0.896561 beta-lactamase_I229M,beta-lactamase_229,TEM-1,beta-lactamase,P62593,0.896565,NO,229,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.267,-4.125,2.858,5.0911,0.083,E,B,1,-0.76,1.114,,50,HHH,-1.58767,0.221079,0.00477249,0.896565 Pab1_S165C,Pab1_165,Pab1,Pab1,P04147,0.896565,NO,165,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.146,-4.454,3.308,,0.12,,a,,0.11,,,,BPB,-1.56867,0.175299,0.000307838,0.896565 kka2_1:4_I254H,kka2_1:4_254,Kka2,kka2_1:4,P00552,0.896608,NO,254,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.933,-4.91,2.977,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.168804,0.0132375,0.896608 beta-lactamase_0_G240L,beta-lactamase_0_240,TEM-1,beta-lactamase_0,P62593,0.896615,NO,240,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.0500837,0.00591201,0.896615 beta-lactamase_0_A278I,beta-lactamase_0_278,TEM-1,beta-lactamase_0,P62593,0.896622,NO,278,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.348,-3.123,1.775,,0.015,H,A,0.48,-0.85,4.624,,63.29,HHA,-1.41833,0.0500837,0.0310297,0.896622 beta-lactamase_0_A200E,beta-lactamase_0_200,TEM-1,beta-lactamase_0,P62593,0.896699,NO,200,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.878,-2.662,0.784,,0.757,H,A,0.46,-0.19,16.368,16.368,77.62,HHP,-2.001,0.0500837,0.0060056,0.896699 kka2_1:2_G164Q,kka2_1:2_164,Kka2,kka2_1:2,P00552,0.896736,NO,164,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.869,-4.074,3.205,,0.862,T,l,0.75,1.45,1.539,,64.39,POH,-1.828,0.295029,0.00442091,0.896736 beta-lactamase_G251F,beta-lactamase_251,TEM-1,beta-lactamase,P62593,0.896737,NO,251,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.907,-4.381,2.474,5.33865,0.506,T,l,0.73,0.17,10.663,,65.38,AOB,-2.06067,0.221079,0.00733416,0.896737 beta-lactamase_X287L,beta-lactamase_287,TEM-1,beta-lactamase,P62593,0.896785,NO,287,X,L,XL,Stop,Hydrophobic,5.71,9.7088,3.9988,,132.5,131,-1,141.9,166.7,24.8,,,,,,,,,,,,,HXO,-1.111,0.221079,,0.896785 kka2_1:2_Q252F,kka2_1:2_252,Kka2,kka2_1:2,P00552,0.896804,NO,252,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.63,-4.468,1.838,,0.906,H,A,0.64,0.35,5.613,,92.05,PPB,-2.20733,0.295029,0.0121001,0.896804 beta-lactamase_0_L136M,beta-lactamase_0_136,TEM-1,beta-lactamase_0,P62593,0.896807,NO,136,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.232,-2.988,1.756,,,H,A,0.55,-0.34,0.648,,48.95,HHH,-1.088,0.0500837,0.00442304,0.896807 beta-lactamase_156_L219G,beta-lactamase_156_219,TEM-1,beta-lactamase_156,P62593,0.896843,NO,219,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.313,-3.865,2.552,,,I,A,0.55,-0.51,2.321,,74.48,HHB,-1.21533,0.111618,0.00664345,0.896843 kka2_1:4_P128M,kka2_1:4_128,Kka2,kka2_1:4,P00552,0.896845,NO,128,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.922,-4.47,2.548,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.168804,0.00774689,0.896845 beta-lactamase_0_R257H,beta-lactamase_0_257,TEM-1,beta-lactamase_0,P62593,0.896873,NO,257,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.0500837,0.00756629,0.896873 kka2_1:8_Q219H,kka2_1:8_219,Kka2,kka2_1:8,P00552,0.896875,NO,219,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-0.93,-4.282,3.352,,0.088,H,A,0.4,-0.85,0.897,,50,HPA,-1.05167,0.100394,0.00237913,0.896875 kka2_1:8_Q219H,kka2_1:8_219,Kka2,kka2_1:8,P00552,0.896875,NO,219,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-0.93,-4.282,3.352,,0.088,H,A,0.4,-0.85,0.897,,50,HPA,-1.05167,0.100394,0.00237913,0.896875 Pab1_K166Q,Pab1_166,Pab1,Pab1,P04147,0.896879,NO,166,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.262,-3.342,2.08,,0.299,,l,,0,,,,PBO,-1.21033,0.175299,0.0011038,0.896879 beta-lactamase_0_T107D,beta-lactamase_0_107,TEM-1,beta-lactamase_0,P62593,0.896894,NO,107,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.117,-3.478,2.361,,,G,A,0.22,-0.06,3.73,,67.83,HPA,-1.265,0.0500837,0.00239347,0.896894 beta-lactamase_G216L,beta-lactamase_216,TEM-1,beta-lactamase,P62593,0.896902,NO,216,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.477,-3.78,2.303,4.91694,0.437,I,A,0.23,-0.58,1.718,,74.48,HOO,-1.68067,0.221079,0.00639568,0.896902 Pab1_S165R,Pab1_165,Pab1,Pab1,P04147,0.896919,NO,165,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.146,-3.525,2.379,,0.12,,a,,0.11,,,,BPB,-1.56867,0.175299,0.000307838,0.896919 kka2_1:4_P12T,kka2_1:4_12,Kka2,kka2_1:4,P00552,0.897069,NO,12,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.853,-3.419,2.566,,,,B,0.52,1.25,0.843,,48.11,POH,-1.80767,0.168804,0.00500011,0.897069 beta-lactamase_39_Y262H,beta-lactamase_39_262,TEM-1,beta-lactamase_39,P62593,0.897127,NO,262,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.0495842,0.00853516,0.897127 Pab1_S155W,Pab1_155,Pab1,Pab1,P04147,0.897149,NO,155,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.039,-5.123,3.084,,,,,,,,,,PPB,-1.42267,0.175299,0.00208179,0.897149 beta-lactamase_0_K71E,beta-lactamase_0_71,TEM-1,beta-lactamase_0,P62593,0.89715,NO,71,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-0.8,-2.99,2.19,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.0500837,0.00103192,0.89715 beta-lactamase_L55K,beta-lactamase_55,TEM-1,beta-lactamase,P62593,0.89716,NO,55,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.86,-3.791,1.931,,0.372,E,A,1.07,-0.36,1.423,,63.99,HHA,-2.247,0.221079,0.00403741,0.89716 beta-lactamase_0_P172V,beta-lactamase_0_172,TEM-1,beta-lactamase_0,P62593,0.897172,NO,172,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.998,-3.483,2.485,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.0500837,0.00312594,0.897172 beta-lactamase_0_S241F,beta-lactamase_0_241,TEM-1,beta-lactamase_0,P62593,0.897214,NO,241,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.0500837,0.00452736,0.897214 beta-lactamase_2500_N274S,beta-lactamase_2500_274,TEM-1,beta-lactamase_2500,P62593,0.897229,NO,274,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.361275,0.0110418,0.897229 kka2_1:4_M148V,kka2_1:4_148,Kka2,kka2_1:4,P00552,0.897269,NO,148,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.847,-1.708,-0.139,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.168804,0.00982664,0.897269 PSD95pdz3_A382F,PSD95pdz3_382,PSD95pdz3,PSD95pdz3,P31016,0.897277,NO,382,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.307,-3.749,2.442,5.30282,,,,,22.472,,,,PHO,-1.24167,0.0758425,0.000249256,0.897277 beta-lactamase_L55H,beta-lactamase_55,TEM-1,beta-lactamase,P62593,0.897283,NO,55,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.86,-4.855,2.995,,0.372,E,A,1.07,-0.36,1.423,,63.99,HHA,-2.247,0.221079,0.00403741,0.897283 beta-lactamase_M268Y,beta-lactamase_268,TEM-1,beta-lactamase,P62593,0.897283,NO,268,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-2.023,-3.805,1.782,5.4797,0.471,H,A,0.09,0.3,1.071,,65.73,PHA,-2.16233,0.221079,0.0102525,0.897283 PSD95pdz3_Y392V,PSD95pdz3_392,PSD95pdz3,PSD95pdz3,P31016,0.897284,NO,392,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-1.437,-2.985,1.548,5.20337,,,,,11.725,,,,PHB,-1.51733,0.0758425,0.000935211,0.897284 beta-lactamase_A222F,beta-lactamase_222,TEM-1,beta-lactamase,P62593,0.897339,NO,222,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.103,-4.23,2.127,5.2262,0.233,H,A,0.47,-0.25,0.379,,77.62,PHH,-1.63733,0.221079,0.00466094,0.897339 kka2_1:2_A150G,kka2_1:2_150,Kka2,kka2_1:2,P00552,0.897364,NO,150,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.949,-2.199,1.25,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.295029,0.0045009,0.897364 beta-lactamase_A183K,beta-lactamase_183,TEM-1,beta-lactamase,P62593,0.89738,NO,183,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.231,-3.508,2.277,4.84712,0.155,H,A,0.55,-0.91,12.189,,77.62,HHH,-1.53367,0.221079,0.00296631,0.89738 kka2_1:8_L223M,kka2_1:8_223,Kka2,kka2_1:8,P00552,0.897392,NO,223,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.861,-3.916,3.055,,,H,A,1.59,-1.24,1.017,,50,HHH,-0.854333,0.100394,0.00253574,0.897392 kka2_1:8_L223M,kka2_1:8_223,Kka2,kka2_1:8,P00552,0.897392,NO,223,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.861,-3.916,3.055,,,H,A,1.59,-1.24,1.017,,50,HHH,-0.854333,0.100394,0.00253574,0.897392 Pab1_K140M,Pab1_140,Pab1,Pab1,P04147,0.897442,NO,140,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.083,-4.297,3.214,,0.345,H,A,,-0.73,,,,PBH,-1.20767,0.175299,0.000337366,0.897442 beta-lactamase_0_D231T,beta-lactamase_0_231,TEM-1,beta-lactamase_0,P62593,0.897446,NO,231,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.816,-3.447,2.631,,,E,B,0.75,-1.06,4.975,,65.38,HAB,-0.994,0.0500837,0.00107395,0.897446 kka2_1:4_S32T,kka2_1:4_32,Kka2,kka2_1:4,P00552,0.897478,NO,32,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-0.804,-3,2.196,,0.768,S,b,0.27,3.75,,,,OPA,-1.74533,0.168804,0.00149998,0.897478 beta-lactamase_A132S,beta-lactamase_132,TEM-1,beta-lactamase,P62593,0.897493,NO,132,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.9,-2.411,1.511,4.58504,,H,A,2.34,-0.93,2.217,,64.69,PHH,-1.138,0.221079,0.000962524,0.897493 kka2_1:8_R140Y,kka2_1:8_140,Kka2,kka2_1:8,P00552,0.897554,NO,140,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.351,-4.311,2.96,,0.12,H,A,0.16,0.2,2.874,,53.03,BBH,-1.885,0.100394,0.00430167,0.897554 kka2_1:8_R140Y,kka2_1:8_140,Kka2,kka2_1:8,P00552,0.897554,NO,140,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.351,-4.311,2.96,,0.12,H,A,0.16,0.2,2.874,,53.03,BBH,-1.885,0.100394,0.00430167,0.897554 Pab1_G150S,Pab1_150,Pab1,Pab1,P04147,0.89756,NO,150,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.809,-2.978,2.169,,0.287,S,b,0.23,0.53,,,,HOA,-1.45233,0.175299,0.000323835,0.89756 PSD95pdz3_F337C,PSD95pdz3_337,PSD95pdz3,PSD95pdz3,P31016,0.89757,NO,337,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.524,-4.544,3.02,5.22838,,,,,13.4936,,,,HHH,-1.59467,0.0758425,0.000875287,0.89757 beta-lactamase_T187V,beta-lactamase_187,TEM-1,beta-lactamase,P62593,0.897579,NO,187,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.401,-3.287,1.886,5.11453,0.007,H,A,0.3,-1.19,1.751,,67.48,PPH,-1.69633,0.221079,0.00491782,0.897579 kka2_1:1_L7S,kka2_1:1_7,Kka2,kka2_1:1,P00552,0.897587,NO,7,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.926,-3.278,1.352,,,,,,,18.934,18.934,71.59,OHB,-2.12333,0.520039,0.00269456,0.897587 PSD95pdz3_R318I,PSD95pdz3_318,PSD95pdz3,PSD95pdz3,P31016,0.897589,NO,318,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.582,-3.692,2.11,4.94876,,,,,17.5609,,,,BBO,-1.40567,0.0758425,0.00110471,0.897589 beta-lactamase_0_T193S,beta-lactamase_0_193,TEM-1,beta-lactamase_0,P62593,0.897591,NO,193,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.914,-2.571,0.657,,0.439,H,a,0.22,0.33,11.546,11.546,63.99,HPO,-1.52133,0.0500837,0.00482669,0.897591 beta-lactamase_G154D,beta-lactamase_154,TEM-1,beta-lactamase,P62593,0.897626,NO,154,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.823,-2.317,1.494,5.40944,0.54,T,l,0.77,-0.56,2.283,,64.69,HOA,-1.635,0.221079,0.00180205,0.897626 beta-lactamase_L28S,beta-lactamase_28,TEM-1,beta-lactamase,P62593,0.897626,NO,28,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.579,-3.523,1.944,5.42969,0.277,H,A,0.07,-0.16,19.748,19.748,93.01,PHH,-2.11333,0.221079,0.00359321,0.897626 kka2_1:4_G55A,kka2_1:4_55,Kka2,kka2_1:4,P00552,0.897639,NO,55,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.625,-2.457,0.832,,0.517,S,b,0.75,1.19,15.753,15.753,63.64,POH,-2.05967,0.168804,0.00667877,0.897639 kka2_1:2_L57M,kka2_1:2_57,Kka2,kka2_1:2,P00552,0.897655,NO,57,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.898,-4.404,2.506,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.295029,0.00723769,0.897655 beta-lactamase_2500_S96W,beta-lactamase_2500_96,TEM-1,beta-lactamase_2500,P62593,0.897663,NO,96,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.27,-5.497,3.227,,0.368,,b,0.27,0.39,32.348,32.348,73.78,HPP,-2.019,0.361275,0.00551835,0.897663 PSD95pdz3_A375G,PSD95pdz3_375,PSD95pdz3,PSD95pdz3,P31016,0.897676,NO,375,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.307,-2.59,1.283,5.05512,,,,,13.888,,,,PHH,-1.43767,0.0758425,0.000356809,0.897676 beta-lactamase_0_A278P,beta-lactamase_0_278,TEM-1,beta-lactamase_0,P62593,0.897749,NO,278,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.348,,,,0.015,H,A,0.48,-0.85,4.624,,63.29,HHA,-1.41833,0.0500837,0.0310297,0.897749 beta-lactamase_W163D,beta-lactamase_163,TEM-1,beta-lactamase,P62593,0.897785,NO,163,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-1.843,-3.903,2.06,6.2765,0.467,,B,1.22,-0.5,3.642,,63.99,BHA,-1.269,0.221079,0.00418955,0.897785 beta-lactamase_39_G240E,beta-lactamase_39_240,TEM-1,beta-lactamase_39,P62593,0.897795,NO,240,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.0495842,0.00591201,0.897795 kka2_1:8_P132S,kka2_1:8_132,Kka2,kka2_1:8,P00552,0.897796,NO,132,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.775,-2.585,1.81,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.100394,0.0018489,0.897796 kka2_1:8_P132S,kka2_1:8_132,Kka2,kka2_1:8,P00552,0.897796,NO,132,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.775,-2.585,1.81,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.100394,0.0018489,0.897796 beta-lactamase_0_G281D,beta-lactamase_0_281,TEM-1,beta-lactamase_0,P62593,0.897861,NO,281,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.0500837,0.0406482,0.897861 beta-lactamase_0_E175S,beta-lactamase_0_175,TEM-1,beta-lactamase_0,P62593,0.897875,NO,175,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.336,-2.863,0.527,,0.551,,A,1.04,1.05,2.334,,77.62,AAB,-1.31233,0.0500837,0.00482205,0.897875 beta-lactamase_A183C,beta-lactamase_183,TEM-1,beta-lactamase,P62593,0.897876,NO,183,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.231,-4.684,3.453,4.84712,0.155,H,A,0.55,-0.91,12.189,,77.62,HHH,-1.53367,0.221079,0.00296631,0.897876 PSD95pdz3_I388T,PSD95pdz3_388,PSD95pdz3,PSD95pdz3,P31016,0.897876,NO,388,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.63,-3.103,1.473,5.17282,,,,,16.0025,,,,PHH,-1.54967,0.0758425,0.000151216,0.897876 beta-lactamase_0_S221R,beta-lactamase_0_221,TEM-1,beta-lactamase_0,P62593,0.897891,NO,221,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.754,-2.83,1.076,,0.624,H,A,0.27,-0.2,2.914,,74.48,BPH,-1.59967,0.0500837,0.0046094,0.897891 kka2_1:1_S68G,kka2_1:1_68,Kka2,kka2_1:1,P00552,0.898026,NO,68,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.623,-2.541,-0.082,,0.48,H,A,0.27,-0.1,2.655,,71.59,HPH,-1.40767,0.520039,0.00608265,0.898026 beta-lactamase_2500_V78L,beta-lactamase_2500_78,TEM-1,beta-lactamase_2500,P62593,0.898044,NO,78,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.459,-1.714,0.255,,,H,A,0.44,-0.47,31.376,31.376,63.64,HHH,-1.17833,0.361275,0.00492501,0.898044 beta-lactamase_0_K32P,beta-lactamase_0_32,TEM-1,beta-lactamase_0,P62593,0.898046,NO,32,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.984,-3.947,1.963,,0.563,H,A,2.34,0.34,0.418,,73.08,HBA,-2.04233,0.0500837,0.00401283,0.898046 beta-lactamase_2500_A278G,beta-lactamase_2500_278,TEM-1,beta-lactamase_2500,P62593,0.898114,NO,278,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.361275,0.0310297,0.898114 beta-lactamase_A170L,beta-lactamase_170,TEM-1,beta-lactamase,P62593,0.898132,NO,170,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.237,-3.289,2.052,5.19261,0.126,,L,2.34,-0.35,2.427,,64.69,AHH,-1.63267,0.221079,0.00431903,0.898132 gb1_V280T,gb1_280,gb1,gb1,P06654,0.898144,NO,280,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.764,-3.114,1.35,,,,,,,0.874,,35.71,PHP,-1.63733,0.177985,0.00321577,0.898144 beta-lactamase_A211V,beta-lactamase_211,TEM-1,beta-lactamase,P62593,0.898165,NO,211,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.896,-3.651,1.755,5.54662,0.369,T,A,0.52,-0.69,2.061,,77.62,AHA,-1.94633,0.221079,0.00648183,0.898165 beta-lactamase_0_N173D,beta-lactamase_0_173,TEM-1,beta-lactamase_0,P62593,0.898169,NO,173,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-2.663,-2.368,-0.295,,1.044,T,l,0.61,1.25,1.133,,77.62,OPA,-1.46633,0.0500837,0.0033769,0.898169 Pab1_K166V,Pab1_166,Pab1,Pab1,P04147,0.898177,NO,166,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.262,-3.489,2.227,,0.299,,l,,0,,,,PBO,-1.21033,0.175299,0.0011038,0.898177 beta-lactamase_0_G76D,beta-lactamase_0_76,TEM-1,beta-lactamase_0,P62593,0.898182,NO,76,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.189,-3.614,2.425,,,H,A,0.29,-0.67,1.188,,67.83,OOH,-1.22267,0.0500837,0.00476637,0.898182 beta-lactamase_2500_W163H,beta-lactamase_2500_163,TEM-1,beta-lactamase_2500,P62593,0.89821,NO,163,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-1.843,-3.378,1.535,,0.467,,B,0.47,-0.5,32.624,32.624,63.99,BHA,-1.269,0.361275,0.00418955,0.89821 beta-lactamase_F70W,beta-lactamase_70,TEM-1,beta-lactamase,P62593,0.898218,NO,70,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.169,-4.623,3.454,5.42055,,H,A,1.1,-1.34,1.14,,63.99,PHB,-0.980667,0.221079,0.00193499,0.898218 kka2_1:8_E142F,kka2_1:8_142,Kka2,kka2_1:8,P00552,0.898268,NO,142,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.221,-4.452,2.231,,0.471,H,A,1.04,0.85,2.655,,65.53,HAB,-2.08033,0.100394,0.00748883,0.898268 kka2_1:8_E142F,kka2_1:8_142,Kka2,kka2_1:8,P00552,0.898268,NO,142,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.221,-4.452,2.231,,0.471,H,A,1.04,0.85,2.655,,65.53,HAB,-2.08033,0.100394,0.00748883,0.898268 Pab1_A141D,Pab1_141,Pab1,Pab1,P04147,0.898319,NO,141,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.461,-3.444,1.983,,0.34,H,A,0.52,-0.27,2.15,,79.03,BHH,-1.19433,0.175299,0.00165974,0.898319 beta-lactamase_2500_G281S,beta-lactamase_2500_281,TEM-1,beta-lactamase_2500,P62593,0.898346,NO,281,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-2.247,-3.28,1.033,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.361275,0.0406482,0.898346 beta-lactamase_625_L79I,beta-lactamase_625_79,TEM-1,beta-lactamase_625,P62593,0.898376,NO,79,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.842,-2.934,2.092,,0.007,H,A,0.55,-0.16,0.935,,50.35,HHP,-1.44333,0.213352,0.000947397,0.898376 kka2_1:2_R253M,kka2_1:2_253,Kka2,kka2_1:2,P00552,0.898414,NO,253,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.356,-4.619,3.263,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.295029,0.0144195,0.898414 beta-lactamase_0_T158A,beta-lactamase_0_158,TEM-1,beta-lactamase_0,P62593,0.898436,NO,158,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.116,-2.879,1.763,,0.036,,B,0.22,-0.85,1.041,,69.58,HPB,-1.269,0.0500837,0.00341825,0.898436 PSD95pdz3_L379V,PSD95pdz3_379,PSD95pdz3,PSD95pdz3,P31016,0.898443,NO,379,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.347,-2.535,1.188,5.37777,,,,,16.8762,,,,HHB,-1.35667,0.0758425,0.00029733,0.898443 WW_domain_P202P,WW_domain_202,Yap65,WW_domain,P46937,0.898471,NO,202,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.4,-1.4,0,5.64207,,,,,,17.28,17.28,78.57,AOB,-1.436,0.153962,0.00212903,0.898471 beta-lactamase_2500_L38Y,beta-lactamase_2500_38,TEM-1,beta-lactamase_2500,P62593,0.898496,NO,38,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.343,-2.956,1.613,,0.088,H,A,0.55,0.2,2.71,,64.34,PHO,-1.78033,0.361275,0.00373244,0.898496 beta-lactamase_2500_S221F,beta-lactamase_2500_221,TEM-1,beta-lactamase_2500,P62593,0.898498,NO,221,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.754,-4.221,2.467,,0.624,H,A,0.27,-0.2,1.971,,74.48,BPH,-1.59967,0.361275,0.0046094,0.898498 beta-lactamase_2500_T264E,beta-lactamase_2500_264,TEM-1,beta-lactamase_2500,P62593,0.898506,NO,264,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.361275,0.0119399,0.898506 beta-lactamase_0_L49P,beta-lactamase_0_49,TEM-1,beta-lactamase_0,P62593,0.898531,NO,49,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.897,-2.49,0.593,,0.131,T,A,0.55,0.04,13.838,13.838,64.69,AHP,-1.99233,0.0500837,0.00401477,0.898531 kka2_1:4_G74V,kka2_1:4_74,Kka2,kka2_1:4,P00552,0.898544,NO,74,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.18,-3.881,2.701,,0.621,T,l,0.75,0.2,1.032,,64.39,POH,-1.91667,0.168804,0.00587035,0.898544 beta-lactamase_156_E164Y,beta-lactamase_156_164,TEM-1,beta-lactamase_156,P62593,0.898553,NO,164,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-0.948,-4.233,3.285,,0.011,T,B,1.04,-0.4,3.445,,64.69,HAO,-1.388,0.111618,0.00137286,0.898553 beta-lactamase_L89F,beta-lactamase_89,TEM-1,beta-lactamase,P62593,0.898566,NO,89,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.096,-3.844,2.748,5.41092,0.168,T,A,1.75,0.63,1.599,,64.34,PHO,-1.75767,0.221079,0.00207068,0.898566 beta-lactamase_156_V117H,beta-lactamase_156_117,TEM-1,beta-lactamase_156,P62593,0.898567,NO,117,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.53,-4.89,3.36,,,H,A,0.44,-0.34,1.182,,65.03,PHB,-1.741,0.111618,0.00467906,0.898567 beta-lactamase_156_A123F,beta-lactamase_156_123,TEM-1,beta-lactamase_156,P62593,0.89857,NO,123,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.834,-4.065,3.231,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.111618,0.0010157,0.89857 beta-lactamase_2500_K213T,beta-lactamase_2500_213,TEM-1,beta-lactamase_2500,P62593,0.898616,NO,213,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.81,-2.431,0.621,,0.67,,A,2.34,0.29,1.668,,67.83,ABH,-1.57767,0.361275,0.00610411,0.898616 beta-lactamase_2500_E210T,beta-lactamase_2500_210,TEM-1,beta-lactamase_2500,P62593,0.89862,NO,210,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.319,-2.842,0.523,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.361275,0.00663582,0.89862 beta-lactamase_2500_R41L,beta-lactamase_2500_41,TEM-1,beta-lactamase_2500,P62593,0.898629,NO,41,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-0.942,-3.384,2.442,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.361275,0.00123327,0.898629 beta-lactamase_0_P250M,beta-lactamase_0_250,TEM-1,beta-lactamase_0,P62593,0.898647,NO,250,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.0500837,0.00550899,0.898647 kka2_1:8_L107T,kka2_1:8_107,Kka2,kka2_1:8,P00552,0.898664,NO,107,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.238,-2.585,1.347,,0.197,.,B,0.55,-1.1,4.478,,71.59,BHH,-2.143,0.100394,0.00561937,0.898664 kka2_1:8_L107T,kka2_1:8_107,Kka2,kka2_1:8,P00552,0.898664,NO,107,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.238,-2.585,1.347,,0.197,.,B,0.55,-1.1,4.478,,71.59,BHH,-2.143,0.100394,0.00561937,0.898664 beta-lactamase_0_G52T,beta-lactamase_0_52,TEM-1,beta-lactamase_0,P62593,0.898668,NO,52,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.149,-3.586,2.437,,0.299,,l,0.29,-0.04,1.164,,64.69,POB,-1.66267,0.0500837,0.00340138,0.898668 kka2_1:8_H135V,kka2_1:8_135,Kka2,kka2_1:8,P00552,0.898681,NO,135,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-1.331,-3.678,2.347,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.100394,0.00532566,0.898681 kka2_1:8_H135V,kka2_1:8_135,Kka2,kka2_1:8,P00552,0.898681,NO,135,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-1.331,-3.678,2.347,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.100394,0.00532566,0.898681 kka2_1:4_L57D,kka2_1:4_57,Kka2,kka2_1:4,P00552,0.89869,NO,57,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.898,-4.048,2.15,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.168804,0.00723769,0.89869 kka2_1:8_R253I,kka2_1:8_253,Kka2,kka2_1:8,P00552,0.898692,NO,253,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.356,-4.056,2.7,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.100394,0.0144195,0.898692 kka2_1:8_R253I,kka2_1:8_253,Kka2,kka2_1:8,P00552,0.898692,NO,253,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.356,-4.056,2.7,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.100394,0.0144195,0.898692 kka2_1:2_V75A,kka2_1:2_75,Kka2,kka2_1:2,P00552,0.898708,NO,75,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-2.06,-3.254,1.194,,0.042,.,B,0.44,-0.2,2.815,,71.59,OHO,-1.563,0.295029,0.00693733,0.898708 beta-lactamase_A9Q,beta-lactamase_9,TEM-1,beta-lactamase,P62593,0.898712,NO,9,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.147,-4.085,1.938,,,,,,,5.128,,72.73,HHH,-2.04267,0.221079,0.00247263,0.898712 beta-lactamase_P253T,beta-lactamase_253,TEM-1,beta-lactamase,P62593,0.898712,NO,253,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-2.253,-2.916,0.663,5.24842,0.308,,B,0.73,-0.46,2.293,,73.08,BOP,-2.10633,0.221079,0.00786358,0.898712 kka2_1:8_R121W,kka2_1:8_121,Kka2,kka2_1:8,P00552,0.898714,NO,121,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.552,-5.451,3.899,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.100394,0.00523326,0.898714 kka2_1:8_R121W,kka2_1:8_121,Kka2,kka2_1:8,P00552,0.898714,NO,121,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.552,-5.451,3.899,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.100394,0.00523326,0.898714 beta-lactamase_0_I261K,beta-lactamase_0_261,TEM-1,beta-lactamase_0,P62593,0.898718,NO,261,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.0500837,0.0123091,0.898718 beta-lactamase_0_Q204W,beta-lactamase_0_204,TEM-1,beta-lactamase_0,P62593,0.89872,NO,204,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-1.382,-5.303,3.921,,0.204,H,A,0.64,0.09,2.646,,66.08,PPH,-1.49067,0.0500837,0.00364106,0.89872 beta-lactamase_2500_L219I,beta-lactamase_2500_219,TEM-1,beta-lactamase_2500,P62593,0.898788,NO,219,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.313,-1.692,0.379,,,I,A,0.55,-0.51,35.994,35.994,74.48,HHB,-1.21533,0.361275,0.00664345,0.898788 beta-lactamase_39_K213I,beta-lactamase_39_213,TEM-1,beta-lactamase_39,P62593,0.898792,NO,213,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.81,-4.142,2.332,,0.67,,A,2.34,0.29,2.648,,67.83,ABH,-1.57767,0.0495842,0.00610411,0.898792 beta-lactamase_0_E62K,beta-lactamase_0_62,TEM-1,beta-lactamase_0,P62593,0.898801,NO,62,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.193,-3.246,2.053,,0.342,S,B,1.04,-0.3,5.784,,73.08,AAB,-1.417,0.0500837,0.00264802,0.898801 beta-lactamase_0_D36I,beta-lactamase_0_36,TEM-1,beta-lactamase_0,P62593,0.898812,NO,36,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.732,-4.112,1.38,,0.555,H,A,0.75,1.17,13.689,13.689,77.62,AAP,-1.91167,0.0500837,0.00476483,0.898812 beta-lactamase_0_G226W,beta-lactamase_0_226,TEM-1,beta-lactamase_0,P62593,0.898826,NO,226,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.461,-5.464,4.003,,0.701,T,l,0.29,-0.25,23.034,23.034,74.48,HOH,-1.42933,0.0500837,0.00665294,0.898826 beta-lactamase_156_T178N,beta-lactamase_156_178,TEM-1,beta-lactamase_156,P62593,0.898863,NO,178,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-0.791,-3.448,2.657,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.111618,0.000684366,0.898863 beta-lactamase_0_D174R,beta-lactamase_0_174,TEM-1,beta-lactamase_0,P62593,0.898933,NO,174,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.738,-3.933,3.195,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.0500837,0.00125633,0.898933 beta-lactamase_0_V157Q,beta-lactamase_0_157,TEM-1,beta-lactamase_0,P62593,0.898982,NO,157,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.751,-4.045,2.294,,0.308,S,a,0.44,-0.75,3.106,,69.58,BHP,-2.00767,0.0500837,0.00506849,0.898982 kka2_1:2_L158R,kka2_1:2_158,Kka2,kka2_1:2,P00552,0.899008,NO,158,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.947,-4.189,2.242,,0.095,,B,1.59,0.77,7.588,,63.64,AHA,-1.25333,0.295029,0.00529068,0.899008 kka2_1:2_G74H,kka2_1:2_74,Kka2,kka2_1:2,P00552,0.899056,NO,74,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.18,-4.623,3.443,,0.621,T,l,0.75,0.2,1.446,,64.39,POH,-1.91667,0.295029,0.00587035,0.899056 kka2_1:2_S204R,kka2_1:2_204,Kka2,kka2_1:2,P00552,0.899062,NO,204,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.353,-3.873,2.52,,0.144,E,A,0.27,-1.2,2.442,,65.53,HPO,-0.953333,0.295029,0.00881794,0.899062 PSD95pdz3_V386I,PSD95pdz3_386,PSD95pdz3,PSD95pdz3,P31016,0.899103,NO,386,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.465,-2.342,0.877,5.18836,,,,,17.5429,,,,PHP,-1.463,0.0758425,0.000184509,0.899103 kka2_1:4_L57V,kka2_1:4_57,Kka2,kka2_1:4,P00552,0.899114,NO,57,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.898,-2.47,0.572,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.168804,0.00723769,0.899114 beta-lactamase_L167T,beta-lactamase_167,TEM-1,beta-lactamase,P62593,0.899129,NO,167,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.138,-3.44,2.302,5.13111,0.015,G,A,0.08,-0.63,0.4,,64.69,AHP,-1.30767,0.221079,0.00303566,0.899129 beta-lactamase_2500_T138C,beta-lactamase_2500_138,TEM-1,beta-lactamase_2500,P62593,0.899162,NO,138,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.506,-5.125,2.619,,0.662,H,A,0.22,-0.03,30.445,30.445,73.78,HPP,-1.81233,0.361275,0.00487868,0.899162 beta-lactamase_A185S,beta-lactamase_185,TEM-1,beta-lactamase,P62593,0.899224,NO,185,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.406,-3.291,1.885,4.89877,,H,A,2.34,-1.02,2.999,,65.03,HHP,-1.84033,0.221079,0.00467449,0.899224 beta-lactamase_D48S,beta-lactamase_48,TEM-1,beta-lactamase,P62593,0.899224,NO,48,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.101,-3.25,2.149,4.89966,0.189,E,B,0.23,0.21,1.281,,50.35,HAH,-1.62467,0.221079,0.0027273,0.899224 beta-lactamase_P181C,beta-lactamase_181,TEM-1,beta-lactamase,P62593,0.89924,NO,181,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.813,-5.009,4.196,5.14752,,H,A,1.1,-1.14,1.357,,61.54,HOH,-1.795,0.221079,0.000703122,0.89924 beta-lactamase_2500_S57N,beta-lactamase_2500_57,TEM-1,beta-lactamase_2500,P62593,0.899276,NO,57,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.918,-2.953,1.035,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.361275,0.00492804,0.899276 kka2_1:2_P12A,kka2_1:2_12,Kka2,kka2_1:2,P00552,0.899289,NO,12,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.853,-2.153,1.3,,,.,B,0.52,1.25,0.261,,48.11,POH,-1.80767,0.295029,0.00500011,0.899289 beta-lactamase_2500_W163S,beta-lactamase_2500_163,TEM-1,beta-lactamase_2500,P62593,0.899334,NO,163,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-1.843,-3.614,1.771,,0.467,,B,0.47,-0.5,32.624,32.624,63.99,BHA,-1.269,0.361275,0.00418955,0.899334 beta-lactamase_0_E169W,beta-lactamase_0_169,TEM-1,beta-lactamase_0,P62593,0.899374,NO,169,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.23,-5.379,4.149,,0.337,,A,1.04,1,3.516,,73.08,PAH,-1.16533,0.0500837,0.00400994,0.899374 beta-lactamase_0_R63P,beta-lactamase_0_63,TEM-1,beta-lactamase_0,P62593,0.899402,NO,63,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-0.943,-3.929,2.986,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.0500837,0.00126938,0.899402 beta-lactamase_0_E210M,beta-lactamase_0_210,TEM-1,beta-lactamase_0,P62593,0.89941,NO,210,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.319,-4.371,2.052,,0.476,H,A,1.04,0.75,3.618,,77.62,HAH,-1.88567,0.0500837,0.00663582,0.89941 beta-lactamase_39_D231C,beta-lactamase_39_231,TEM-1,beta-lactamase_39,P62593,0.899412,NO,231,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.816,-5.136,4.32,,,E,B,0.75,-1.06,0.462,,65.38,HAB,-0.994,0.0495842,0.00107395,0.899412 beta-lactamase_E108Y,beta-lactamase_108,TEM-1,beta-lactamase,P62593,0.899487,NO,108,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.46,-4.347,2.887,5.52079,0.572,G,A,0.52,1.87,1.973,,72.73,PAB,-1.437,0.221079,0.00413372,0.899487 beta-lactamase_E210L,beta-lactamase_210,TEM-1,beta-lactamase,P62593,0.899487,NO,210,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.319,-2.05,-0.269,5.7398,0.476,H,A,0.52,0.75,1.555,,77.62,HAH,-1.88567,0.221079,0.00663582,0.899487 beta-lactamase_F6S,beta-lactamase_6,TEM-1,beta-lactamase,P62593,0.899487,NO,6,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.847,-3.481,1.634,,,,,,,1.276,,67.83,BHB,-2.076,0.221079,0.00261627,0.899487 beta-lactamase_Q203F,beta-lactamase_203,TEM-1,beta-lactamase,P62593,0.899487,NO,203,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.168,-4.379,2.211,5.65296,0.47,H,A,0.12,-0.38,1.66,,65.38,BPP,-1.614,0.221079,0.00631514,0.899487 beta-lactamase_39_E272Q,beta-lactamase_39_272,TEM-1,beta-lactamase_39,P62593,0.899562,NO,272,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.127,,,,0.081,H,A,0.43,-0.97,12.983,12.983,63.64,AAB,-1.56333,0.0495842,0.00545371,0.899562 kka2_1:4_G164N,kka2_1:4_164,Kka2,kka2_1:4,P00552,0.899605,NO,164,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.869,-2.458,1.589,,0.862,T,l,0.75,1.45,1.539,,64.39,POH,-1.828,0.168804,0.00442091,0.899605 kka2_1:4_L60R,kka2_1:4_60,Kka2,kka2_1:4,P00552,0.899636,NO,60,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.997,-4.088,3.091,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.168804,0.00262176,0.899636 kka2_1:4_S104K,kka2_1:4_104,Kka2,kka2_1:4,P00552,0.89965,NO,104,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.436,-3.48,2.044,,0.536,T,A,0.27,-1.11,0.357,,63.64,HPP,-1.91433,0.168804,0.00555207,0.89965 WW_domain_S183M,WW_domain_183,Yap65,WW_domain,P46937,0.899681,NO,183,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.95,-4.577,2.627,5.35576,,,,,,1.594,,83.93,PPP,-1.48733,0.153962,0.00445513,0.899681 kka2_1:2_Q155H,kka2_1:2_155,Kka2,kka2_1:2,P00552,0.899699,NO,155,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.606,-4.51,1.904,,0.525,T,A,0.64,1.49,1.592,,63.64,APA,-1.726,0.295029,0.00641853,0.899699 kka2_1:1_I2R,kka2_1:1_2,Kka2,kka2_1:1,P00552,0.899706,NO,2,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.787,-3.848,2.061,,,,,,,2.329,,71.59,HHA,-1.92433,0.520039,0.00246644,0.899706 beta-lactamase_A34L,beta-lactamase_34,TEM-1,beta-lactamase,P62593,0.899724,NO,34,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.059,-2.191,0.132,4.9129,,H,A,0.75,-0.54,3.614,,73.78,AHA,-1.74967,0.221079,0.00407913,0.899724 beta-lactamase_2500_H287E,beta-lactamase_2500_287,TEM-1,beta-lactamase_2500,P62593,0.899742,NO,287,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,,,,,,,,,,,,,BBH,-1.111,0.361275,,0.899742 beta-lactamase_2500_R239T,beta-lactamase_2500_239,TEM-1,beta-lactamase_2500,P62593,0.899769,NO,239,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.361275,0.00213852,0.899769 kka2_1:2_K50R,kka2_1:2_50,Kka2,kka2_1:2,P00552,0.899774,NO,50,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-0.833,-2.445,1.612,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.295029,0.00138626,0.899774 beta-lactamase_0_G265A,beta-lactamase_0_265,TEM-1,beta-lactamase_0,P62593,0.899829,NO,265,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.0500837,0.00811926,0.899829 beta-lactamase_P165N,beta-lactamase_165,TEM-1,beta-lactamase,P62593,0.899855,NO,165,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.373,-3.703,2.33,5.33889,0.203,T,A,0.99,-0.31,0.414,,73.78,AOA,-1.359,0.221079,0.00549538,0.899855 beta-lactamase_0_A40V,beta-lactamase_0_40,TEM-1,beta-lactamase_0,P62593,0.899887,NO,40,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.402,-2.649,1.247,,0.155,S,B,0.46,0.21,0.783,,73.78,OHB,-1.40267,0.0500837,0.00490026,0.899887 kka2_1:2_A110S,kka2_1:2_110,Kka2,kka2_1:2,P00552,0.89989,NO,110,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.064,-2.748,0.684,,0.175,H,A,0.46,-1.19,23.237,23.237,71.59,OHA,-1.91867,0.295029,0.00759851,0.89989 beta-lactamase_0_E175W,beta-lactamase_0_175,TEM-1,beta-lactamase_0,P62593,0.899896,NO,175,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.336,-5.537,3.201,,0.551,,A,1.04,1.05,2.334,,77.62,AAB,-1.31233,0.0500837,0.00482205,0.899896 beta-lactamase_2500_K213F,beta-lactamase_2500_213,TEM-1,beta-lactamase_2500,P62593,0.89991,NO,213,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.81,-4.437,2.627,,0.67,,A,2.34,0.29,1.668,,67.83,ABH,-1.57767,0.361275,0.00610411,0.89991 gb1_A246M,gb1_246,gb1,gb1,P06654,0.899952,NO,246,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.175,-4.215,3.04,,,,,,,,,,AHH,-1.87033,0.177985,0.00190625,0.899952 beta-lactamase_0_G39W,beta-lactamase_0_39,TEM-1,beta-lactamase_0,P62593,0.899975,NO,39,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.864,-5.517,3.653,,0.701,T,L,0.29,0.47,4.111,,77.62,HOH,-1.53633,0.0500837,0.00487611,0.899975 beta-lactamase_0_T158G,beta-lactamase_0_158,TEM-1,beta-lactamase_0,P62593,0.899981,NO,158,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.116,-3.288,2.172,,0.036,,B,0.22,-0.85,1.041,,69.58,HPB,-1.269,0.0500837,0.00341825,0.899981 beta-lactamase_156_D83Y,beta-lactamase_156_83,TEM-1,beta-lactamase_156,P62593,0.899987,NO,83,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.066,-4.396,3.33,,0.354,H,A,0.75,0.22,1.281,,48.95,HAH,-1.34733,0.111618,0.00205968,0.899987 kka2_1:2_R253Q,kka2_1:2_253,Kka2,kka2_1:2,P00552,0.899999,NO,253,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.356,-3.67,2.314,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.295029,0.0144195,0.899999 beta-lactamase_0_R176S,beta-lactamase_0_176,TEM-1,beta-lactamase_0,P62593,0.900017,NO,176,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-0.863,-3.386,2.523,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.0500837,0.00105554,0.900017 beta-lactamase_39_M67K,beta-lactamase_39_67,TEM-1,beta-lactamase_39,P62593,0.900078,NO,67,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-2.231,-3.7,1.469,,0.006,G,P,0.55,-0.81,1.463,,65.03,HHP,-1.502,0.0495842,0.00409753,0.900078 beta-lactamase_0_R162P,beta-lactamase_0_162,TEM-1,beta-lactamase_0,P62593,0.900131,NO,162,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.016,-2.671,1.655,,0.124,S,B,1.2,-0.37,1.026,,64.69,ABH,-1.25,0.0500837,0.000561334,0.900131 beta-lactamase_39_E272M,beta-lactamase_39_272,TEM-1,beta-lactamase_39,P62593,0.900153,NO,272,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.127,,,,0.081,H,A,0.43,-0.97,12.983,12.983,63.64,AAB,-1.56333,0.0495842,0.00545371,0.900153 kka2_1:1_H8D,kka2_1:1_8,Kka2,kka2_1:1,P00552,0.900179,NO,8,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-2.759,-3.533,0.774,,,,,,,16.971,16.971,71.59,HBH,-2.25467,0.520039,0.00256422,0.900179 beta-lactamase_0_K144L,beta-lactamase_0_144,TEM-1,beta-lactamase_0,P62593,0.900185,NO,144,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-2.388,-3.577,1.189,,0.863,H,A,2.34,1.27,5.696,,77.62,OBA,-1.904,0.0500837,0.00481141,0.900185 beta-lactamase_P249N,beta-lactamase_249,TEM-1,beta-lactamase,P62593,0.900232,NO,249,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.312,-3.85,2.538,5.10655,0.256,S,B,0.99,0.04,0.479,,72.73,OOA,-1.81367,0.221079,0.00220169,0.900232 beta-lactamase_2500_P165V,beta-lactamase_2500_165,TEM-1,beta-lactamase_2500,P62593,0.900253,NO,165,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.373,-3.333,1.96,,0.203,T,A,0.52,-0.31,0.414,,73.78,AOA,-1.359,0.361275,0.00549538,0.900253 kka2_1:8_A71L,kka2_1:8_71,Kka2,kka2_1:8,P00552,0.900254,NO,71,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.824,-3.593,1.769,,0.553,H,A,0.46,0.08,18.64,18.64,64.39,HHP,-1.74033,0.100394,0.00727707,0.900254 kka2_1:8_A71L,kka2_1:8_71,Kka2,kka2_1:8,P00552,0.900254,NO,71,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.824,-3.593,1.769,,0.553,H,A,0.46,0.08,18.64,18.64,64.39,HHP,-1.74033,0.100394,0.00727707,0.900254 beta-lactamase_39_Y95R,beta-lactamase_39_95,TEM-1,beta-lactamase_39,P62593,0.900265,NO,95,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-1.715,-4.186,2.471,,0.122,,b,0.21,-0.37,2.341,,77.62,BHP,-2.16167,0.0495842,0.00479449,0.900265 kka2_1:4_F203L,kka2_1:4_203,Kka2,kka2_1:4,P00552,0.900265,NO,203,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-0.911,-2.161,1.25,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.168804,0.00318738,0.900265 beta-lactamase_0_S96R,beta-lactamase_0_96,TEM-1,beta-lactamase_0,P62593,0.900291,NO,96,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.27,-2.133,-0.137,,0.368,,b,0.27,0.39,2.516,,73.78,HPP,-2.019,0.0500837,0.00551835,0.900291 beta-lactamase_H110G,beta-lactamase_110,TEM-1,beta-lactamase,P62593,0.900309,NO,110,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-1.706,-3.573,1.867,5.52635,0.341,G,a,0.35,1.08,31.31,31.31,64.69,BBH,-1.73333,0.221079,0.00441499,0.900309 kka2_1:8_F203C,kka2_1:8_203,Kka2,kka2_1:8,P00552,0.900365,NO,203,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-0.911,-4.889,3.978,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.100394,0.00318738,0.900365 kka2_1:8_F203C,kka2_1:8_203,Kka2,kka2_1:8,P00552,0.900365,NO,203,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-0.911,-4.889,3.978,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.100394,0.00318738,0.900365 beta-lactamase_2500_T139H,beta-lactamase_2500_139,TEM-1,beta-lactamase_2500,P62593,0.900369,NO,139,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.901,-3.291,1.39,,0.216,H,A,0.22,0.39,2.256,,77.62,PPH,-2.04667,0.361275,0.00441837,0.900369 beta-lactamase_V214A,beta-lactamase_214,TEM-1,beta-lactamase,P62593,0.900382,NO,214,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.299,-2.434,1.135,5.74008,0.375,S,A,1.19,-0.44,1.899,,74.48,BHH,-1.53733,0.221079,0.00628442,0.900382 beta-lactamase_625_G76W,beta-lactamase_625_76,TEM-1,beta-lactamase_625,P62593,0.900435,NO,76,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.189,-5.284,4.095,,,H,A,0.29,-0.67,3.059,,67.83,OOH,-1.22267,0.213352,0.00476637,0.900435 beta-lactamase_2500_T147G,beta-lactamase_2500_147,TEM-1,beta-lactamase_2500,P62593,0.900439,NO,147,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.149,-2.499,1.35,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.361275,0.00226017,0.900439 beta-lactamase_P165I,beta-lactamase_165,TEM-1,beta-lactamase,P62593,0.900439,NO,165,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.373,-3.815,2.442,5.33889,0.203,T,A,0.99,-0.31,0.414,,73.78,AOA,-1.359,0.221079,0.00549538,0.900439 PSD95pdz3_I359A,PSD95pdz3_359,PSD95pdz3,PSD95pdz3,P31016,0.900449,NO,359,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.63,-2.759,1.129,5.35151,,,,,14.8012,,,,PHH,-1.58667,0.0758425,0.000580694,0.900449 beta-lactamase_0_M184T,beta-lactamase_0_184,TEM-1,beta-lactamase_0,P62593,0.900473,NO,184,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.593,-2.764,1.171,,,H,A,0.55,-0.87,13.292,13.292,62.94,HHH,-1.41,0.0500837,0.00356019,0.900473 kka2_1:8_D156Y,kka2_1:8_156,Kka2,kka2_1:8,P00552,0.900476,NO,156,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.696,-4.451,2.755,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.100394,0.00926998,0.900476 kka2_1:8_D156Y,kka2_1:8_156,Kka2,kka2_1:8,P00552,0.900476,NO,156,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.696,-4.451,2.755,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.100394,0.00926998,0.900476 beta-lactamase_0_P143M,beta-lactamase_0_143,TEM-1,beta-lactamase_0,P62593,0.900477,NO,143,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.967,-4.554,3.587,,0.075,H,A,0.52,-0.37,11.868,11.868,66.78,OOB,-1.354,0.0500837,0.00114551,0.900477 kka2_1:8_F256C,kka2_1:8_256,Kka2,kka2_1:8,P00552,0.900499,NO,256,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.49,-3.289,1.799,,,H,A,1.62,-0.78,1.713,,53.03,HHH,-1.423,0.100394,0.0132841,0.900499 kka2_1:8_F256C,kka2_1:8_256,Kka2,kka2_1:8,P00552,0.900499,NO,256,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.49,-3.289,1.799,,,H,A,1.62,-0.78,1.713,,53.03,HHH,-1.423,0.100394,0.0132841,0.900499 kka2_1:2_A137H,kka2_1:2_137,Kka2,kka2_1:2,P00552,0.900531,NO,137,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.156,-4.943,2.787,,0.029,H,A,0.46,0.34,1.323,,63.26,PHB,-2.559,0.295029,0.00515054,0.900531 beta-lactamase_39_K213A,beta-lactamase_39_213,TEM-1,beta-lactamase_39,P62593,0.900576,NO,213,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.81,-3.194,1.384,,0.67,,A,2.34,0.29,2.648,,67.83,ABH,-1.57767,0.0495842,0.00610411,0.900576 beta-lactamase_P249M,beta-lactamase_249,TEM-1,beta-lactamase,P62593,0.900578,NO,249,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.312,-4.668,3.356,5.10655,0.256,S,B,0.99,0.04,0.479,,72.73,OOA,-1.81367,0.221079,0.00220169,0.900578 beta-lactamase_2500_I54W,beta-lactamase_2500_54,TEM-1,beta-lactamase_2500,P62593,0.900599,NO,54,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-2.838,-5.452,2.614,,0.669,E,B,0.48,-0.14,3.946,,73.78,BHH,-2.337,0.361275,0.00403589,0.900599 beta-lactamase_0_P165H,beta-lactamase_0_165,TEM-1,beta-lactamase_0,P62593,0.900642,NO,165,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.373,-4.751,3.378,,0.203,T,A,0.52,-0.31,3.242,,73.78,AOA,-1.359,0.0500837,0.00549538,0.900642 Pab1_F168M,Pab1_168,Pab1,Pab1,P04147,0.900671,NO,168,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.269,-4.176,2.907,,,,,,,0.789,,56.33,OHO,-1.10033,0.175299,0.00064061,0.900671 beta-lactamase_0_V259L,beta-lactamase_0_259,TEM-1,beta-lactamase_0,P62593,0.900775,NO,259,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.0500837,0.0070773,0.900775 beta-lactamase_2500_F58V,beta-lactamase_2500_58,TEM-1,beta-lactamase_2500,P62593,0.900847,NO,58,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-2.914,-3.697,0.783,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.361275,0.00523369,0.900847 gb1_T242C,gb1_242,gb1,gb1,P06654,0.900849,NO,242,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.245,-4.373,3.128,,,,,,,,,,APP,-1.444,0.177985,0.00243886,0.900849 gb1_T242M,gb1_242,gb1,gb1,P06654,0.900849,NO,242,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.245,-4.215,2.97,,,,,,,,,,APP,-1.444,0.177985,0.00243886,0.900849 beta-lactamase_A16Y,beta-lactamase_16,TEM-1,beta-lactamase,P62593,0.900883,NO,16,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,,-4.158,2.223,,,,,,,,,,HHH,,0.221079,0.00245392,0.900883 beta-lactamase_0_A133Y,beta-lactamase_0_133,TEM-1,beta-lactamase_0,P62593,0.900886,NO,133,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.186,-4.319,3.133,,,H,A,0.46,-0.86,2.148,,67.83,HHP,-0.988333,0.0500837,0.00468022,0.900886 beta-lactamase_0_R273Q,beta-lactamase_0_273,TEM-1,beta-lactamase_0,P62593,0.900937,NO,273,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.314,-2.364,0.05,,0.564,H,A,1.2,1.57,20.248,20.248,73.78,ABP,-1.841,0.0500837,0.0077952,0.900937 beta-lactamase_39_T107Y,beta-lactamase_39_107,TEM-1,beta-lactamase_39,P62593,0.900965,NO,107,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.117,-4.214,3.097,,,G,A,0.22,-0.06,2.686,,67.83,HPA,-1.265,0.0495842,0.00239347,0.900965 beta-lactamase_0_Q97L,beta-lactamase_0_97,TEM-1,beta-lactamase_0,P62593,0.900966,NO,97,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.072,-3.528,1.456,,0.823,G,A,0.64,2.42,16.954,16.954,77.62,PPP,-2.43833,0.0500837,0.0045116,0.900966 beta-lactamase_0_A200P,beta-lactamase_0_200,TEM-1,beta-lactamase_0,P62593,0.90102,NO,200,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.878,-2.581,0.703,,0.757,H,A,0.46,-0.19,16.368,16.368,77.62,HHP,-2.001,0.0500837,0.0060056,0.90102 beta-lactamase_2500_S201H,beta-lactamase_2500_201,TEM-1,beta-lactamase_2500,P62593,0.901045,NO,201,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.183,-4.595,3.412,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.361275,0.00198815,0.901045 beta-lactamase_M268T,beta-lactamase_268,TEM-1,beta-lactamase,P62593,0.901111,NO,268,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-2.023,-3.596,1.573,5.4797,0.471,H,A,0.09,0.3,1.071,,65.73,PHA,-2.16233,0.221079,0.0102525,0.901111 gb1_T279F,gb1_279,gb1,gb1,P06654,0.901146,NO,279,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.32,-3.757,2.437,,,,,,,0.529,,35.71,HPH,-1.50067,0.177985,0.00421454,0.901146 beta-lactamase_M268Q,beta-lactamase_268,TEM-1,beta-lactamase,P62593,0.901152,NO,268,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-2.023,-4.084,2.061,5.4797,0.471,H,A,0.09,0.3,1.071,,65.73,PHA,-2.16233,0.221079,0.0102525,0.901152 beta-lactamase_0_M67Q,beta-lactamase_0_67,TEM-1,beta-lactamase_0,P62593,0.901159,NO,67,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-2.231,-4.09,1.859,,0.006,G,P,0.55,-0.81,24.165,24.165,65.03,HHP,-1.502,0.0500837,0.00409753,0.901159 beta-lactamase_0_A235C,beta-lactamase_0_235,TEM-1,beta-lactamase_0,P62593,0.90116,NO,235,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.266,-4.693,3.427,,0.32,E,B,0.46,-0.86,2.261,,50,OHO,-0.89,0.0500837,0.00493474,0.90116 beta-lactamase_0_L79G,beta-lactamase_0_79,TEM-1,beta-lactamase_0,P62593,0.901184,NO,79,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.842,-3.806,2.964,,0.007,H,A,0.55,-0.16,5.053,,50.35,HHP,-1.44333,0.0500837,0.000947397,0.901184 kka2_1:4_T125V,kka2_1:4_125,Kka2,kka2_1:4,P00552,0.901203,NO,125,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.622,-2.85,0.228,,0.791,T,A,0.82,0.33,1.612,,92.05,BPH,-1.56933,0.168804,0.00821755,0.901203 kka2_1:1_A78R,kka2_1:1_78,Kka2,kka2_1:1,P00552,0.901212,NO,78,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.744,-3.937,2.193,,0.078,.,B,0.46,-0.53,0.206,,56.06,OHH,-1.863,0.520039,0.00457299,0.901212 kka2_1:2_V113I,kka2_1:2_113,Kka2,kka2_1:2,P00552,0.90122,NO,113,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.233,-1.634,0.401,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.295029,0.00650191,0.90122 beta-lactamase_0_A282G,beta-lactamase_0_282,TEM-1,beta-lactamase_0,P62593,0.901237,NO,282,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.0500837,0.0449821,0.901237 beta-lactamase_2500_E279H,beta-lactamase_2500_279,TEM-1,beta-lactamase_2500,P62593,0.901237,NO,279,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.361275,0.0192826,0.901237 beta-lactamase_0_P25I,beta-lactamase_0_25,TEM-1,beta-lactamase_0,P62593,0.90128,NO,25,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.526,-4.029,2.503,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.0500837,0.00347571,0.90128 beta-lactamase_0_L89D,beta-lactamase_0_89,TEM-1,beta-lactamase_0,P62593,0.901284,NO,89,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.096,-3.996,2.9,,0.168,T,A,0.55,0.63,2.373,,64.34,PHO,-1.75767,0.0500837,0.00207068,0.901284 beta-lactamase_P249S,beta-lactamase_249,TEM-1,beta-lactamase,P62593,0.901285,NO,249,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.312,-2.754,1.442,5.10655,0.256,S,B,0.99,0.04,0.479,,72.73,OOA,-1.81367,0.221079,0.00220169,0.901285 beta-lactamase_156_P65Y,beta-lactamase_156_65,TEM-1,beta-lactamase_156,P62593,0.901302,NO,65,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.894,-4.31,3.416,,0.098,E,B,0.52,-0.62,0.623,,40.56,HOH,-1.03233,0.111618,0.00152776,0.901302 beta-lactamase_R271C,beta-lactamase_271,TEM-1,beta-lactamase,P62593,0.901308,NO,271,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.249,-5.029,3.78,5.24516,0.085,H,A,1.67,-0.05,0.474,,63.99,ABP,-1.36633,0.221079,0.00752082,0.901308 beta-lactamase_0_G226A,beta-lactamase_0_226,TEM-1,beta-lactamase_0,P62593,0.901328,NO,226,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.461,-2.638,1.177,,0.701,T,l,0.29,-0.25,23.034,23.034,74.48,HOH,-1.42933,0.0500837,0.00665294,0.901328 beta-lactamase_625_R41G,beta-lactamase_625_41,TEM-1,beta-lactamase_625,P62593,0.901366,NO,41,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-0.942,-3.321,2.379,,0.321,E,B,1.2,-0.07,1.186,,65.03,HBH,-1.30267,0.213352,0.00123327,0.901366 beta-lactamase_E277F,beta-lactamase_277,TEM-1,beta-lactamase,P62593,0.901426,NO,277,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.869,-4.409,2.54,5.51786,0.545,H,A,0.52,-0.01,2.022,,77.62,HAH,-1.45367,0.221079,0.0169305,0.901426 beta-lactamase_Y260I,beta-lactamase_260,TEM-1,beta-lactamase,P62593,0.901426,NO,260,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-1.101,-3.484,2.383,5.50878,,E,B,0.73,-1.04,0.865,,60.49,HHP,-1.83433,0.221079,0.00471757,0.901426 Pab1_V171T,Pab1_171,Pab1,Pab1,P04147,0.901445,NO,171,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.113,-3.014,1.901,,0.008,E,b,0.23,-0.34,,,,HHB,-1.19733,0.175299,0.000298662,0.901445 Pab1_A179C,Pab1_179,Pab1,Pab1,P04147,0.901464,NO,179,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.013,-4.229,3.216,,0.078,H,A,0.61,0.5,,,,HHB,-1.51233,0.175299,0.000291703,0.901464 beta-lactamase_0_R91C,beta-lactamase_0_91,TEM-1,beta-lactamase_0,P62593,0.901486,NO,91,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.392,-5.127,3.735,,0.444,,B,1.2,0.96,4.557,,50.35,OBB,-1.73367,0.0500837,0.00380226,0.901486 kka2_1:8_P194N,kka2_1:8_194,Kka2,kka2_1:8,P00552,0.901496,NO,194,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.846,-3.808,2.962,,0.308,G,A,0.52,-1.19,4.861,,53.03,HOP,-0.888333,0.100394,0.00314194,0.901496 kka2_1:8_P194N,kka2_1:8_194,Kka2,kka2_1:8,P00552,0.901496,NO,194,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.846,-3.808,2.962,,0.308,G,A,0.52,-1.19,4.861,,53.03,HOP,-0.888333,0.100394,0.00314194,0.901496 beta-lactamase_625_V101W,beta-lactamase_625_101,TEM-1,beta-lactamase_625,P62593,0.901503,NO,101,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.295,-5.385,4.09,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.213352,0.00374492,0.901503 beta-lactamase_0_D207M,beta-lactamase_0_207,TEM-1,beta-lactamase_0,P62593,0.901529,NO,207,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.064,-4.822,2.758,,0.409,H,A,0.75,0.12,5.277,,77.62,HAH,-1.77033,0.0500837,0.00592942,0.901529 beta-lactamase_0_G141L,beta-lactamase_0_141,TEM-1,beta-lactamase_0,P62593,0.90155,NO,141,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.828,-3.844,3.016,,0.575,T,l,0.29,-0.28,0.722,,64.69,HOO,-1.08933,0.0500837,0.0012419,0.90155 beta-lactamase_39_G236F,beta-lactamase_39_236,TEM-1,beta-lactamase_39,P62593,0.901596,NO,236,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.784,-4.291,3.507,,0.241,,b,0.29,-0.59,1.883,,64.69,HOO,-1.025,0.0495842,0.00162372,0.901596 beta-lactamase_R63H,beta-lactamase_63,TEM-1,beta-lactamase,P62593,0.901635,NO,63,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-0.943,-4.313,3.37,5.49979,0.218,,B,0.45,-0.31,0.677,,44.06,ABH,-0.992333,0.221079,0.00126938,0.901635 kka2_1:8_D101H,kka2_1:8_101,Kka2,kka2_1:8,P00552,0.901675,NO,101,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.028,-4.537,3.509,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.100394,0.00423361,0.901675 kka2_1:8_D101H,kka2_1:8_101,Kka2,kka2_1:8,P00552,0.901675,NO,101,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.028,-4.537,3.509,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.100394,0.00423361,0.901675 beta-lactamase_0_K286H,beta-lactamase_0_286,TEM-1,beta-lactamase_0,P62593,0.901677,NO,286,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.0500837,,0.901677 beta-lactamase_0_Q97F,beta-lactamase_0_97,TEM-1,beta-lactamase_0,P62593,0.901693,NO,97,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.072,-4.44,2.368,,0.823,G,A,0.64,2.42,16.954,16.954,77.62,PPP,-2.43833,0.0500837,0.0045116,0.901693 kka2_1:4_D101Q,kka2_1:4_101,Kka2,kka2_1:4,P00552,0.901693,NO,101,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.028,-3.859,2.831,,0.213,E,B,0.75,-1.24,8.707,,63.64,PAH,-1.534,0.168804,0.00423361,0.901693 gb1_T242H,gb1_242,gb1,gb1,P06654,0.90174,NO,242,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.245,-4.416,3.171,,,,,,,,,,APP,-1.444,0.177985,0.00243886,0.90174 beta-lactamase_0_G243C,beta-lactamase_0_243,TEM-1,beta-lactamase_0,P62593,0.901741,NO,243,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.0500837,0.00464034,0.901741 kka2_1:4_Q136C,kka2_1:4_136,Kka2,kka2_1:4,P00552,0.901755,NO,136,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-3.021,-3.362,0.341,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.168804,0.00624149,0.901755 beta-lactamase_0_A34G,beta-lactamase_0_34,TEM-1,beta-lactamase_0,P62593,0.901851,NO,34,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.059,-3.469,1.41,,,H,A,0.46,-0.54,3.998,,73.78,AHA,-1.74967,0.0500837,0.00407913,0.901851 WW_domain_M179L,WW_domain_179,Yap65,WW_domain,P46937,0.901852,NO,179,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.541,-2.235,0.694,6.54704,,,,,,,,,AHH,-1.31367,0.153962,0.00400164,0.901852 beta-lactamase_D99K,beta-lactamase_99,TEM-1,beta-lactamase,P62593,0.90194,NO,99,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.191,-3.447,2.256,5.66081,0.402,G,A,0.23,0.36,1.318,,64.69,PAH,-1.794,0.221079,0.00305446,0.90194 hsp90_N588Q,hsp90_588,hsp90,hsp90,P02829,0.90194,NO,588,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-3.051,-3.278,0,4.61142,0.019,H,A,0.14,0.39,,,,HPH,-3.12167,0.368192,0.000222939,0.90194 kka2_1:1_L7V,kka2_1:1_7,Kka2,kka2_1:1,P00552,0.901953,NO,7,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.926,-3.173,1.247,,,,,,,18.934,18.934,71.59,OHB,-2.12333,0.520039,0.00269456,0.901953 beta-lactamase_0_K109C,beta-lactamase_0_109,TEM-1,beta-lactamase_0,P62593,0.901971,NO,109,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.734,-5.237,3.503,,0.787,G,A,2.34,2.21,15.473,15.473,72.73,ABB,-1.63333,0.0500837,0.00462493,0.901971 beta-lactamase_L111R,beta-lactamase_111,TEM-1,beta-lactamase,P62593,0.901993,NO,111,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.76,-4.077,2.317,5.8705,0.328,T,A,0.84,0.93,3.836,,64.34,BHP,-1.884,0.221079,0.00480671,0.901993 gb1_G264C,gb1_264,gb1,gb1,P06654,0.902036,NO,264,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.833,-4.733,2.9,,,,,,,0.864,,44.87,POH,-1.61267,0.177985,0.0049716,0.902036 beta-lactamase_0_A247H,beta-lactamase_0_247,TEM-1,beta-lactamase_0,P62593,0.902046,NO,247,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.0500837,0.00611275,0.902046 beta-lactamase_K32F,beta-lactamase_32,TEM-1,beta-lactamase,P62593,0.902105,NO,32,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.984,-4.328,2.344,5.55842,0.563,H,A,1.82,0.34,1.754,,73.08,HBA,-2.04233,0.221079,0.00401283,0.902105 WW_domain_L190V,WW_domain_190,Yap65,WW_domain,P46937,0.902179,NO,190,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.404,-2.918,1.514,5.53598,,,,,,0.645,,56.55,HHP,-1.51833,0.153962,0.00249186,0.902179 beta-lactamase_0_V72A,beta-lactamase_0_72,TEM-1,beta-lactamase_0,P62593,0.902218,NO,72,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.658,-1.729,0.071,,,H,A,0.44,-1.03,2.964,,65.73,BHH,-1.32167,0.0500837,0.00501194,0.902218 kka2_1:1_V242S,kka2_1:1_242,Kka2,kka2_1:1,P00552,0.902218,NO,242,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-2.687,-3.455,0.768,,0.75,H,A,0.44,-0.37,4.987,,71.59,HHH,-2.16533,0.520039,0.0102575,0.902218 kka2_1:4_E59L,kka2_1:4_59,Kka2,kka2_1:4,P00552,0.902255,NO,59,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-0.952,-3.625,2.673,,0.187,.,L,1.04,0.62,3.408,,50.38,PAH,-1.53,0.168804,0.00280355,0.902255 beta-lactamase_0_P25V,beta-lactamase_0_25,TEM-1,beta-lactamase_0,P62593,0.902266,NO,25,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.526,-3.565,2.039,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.0500837,0.00347571,0.902266 kka2_1:2_P76Q,kka2_1:2_76,Kka2,kka2_1:2,P00552,0.902268,NO,76,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.449,-3.171,1.722,,0.331,.,B,0.52,-0.41,0.345,,63.64,HOO,-1.662,0.295029,0.00625685,0.902268 Pab1_L153T,Pab1_153,Pab1,Pab1,P04147,0.902321,NO,153,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.039,-3.239,2.2,,0.46,E,A,,-0.95,,,,HHP,-1.17667,0.175299,0.000321212,0.902321 beta-lactamase_0_A183H,beta-lactamase_0_183,TEM-1,beta-lactamase_0,P62593,0.902343,NO,183,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.231,-4.624,3.393,,0.155,H,A,0.46,-0.91,1.48,,77.62,HHH,-1.53367,0.0500837,0.00296631,0.902343 beta-lactamase_0_K286V,beta-lactamase_0_286,TEM-1,beta-lactamase_0,P62593,0.902348,NO,286,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.0500837,,0.902348 beta-lactamase_0_V78G,beta-lactamase_0_78,TEM-1,beta-lactamase_0,P62593,0.902365,NO,78,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.459,-2.817,1.358,,,H,A,0.44,-0.47,16.615,16.615,63.64,HHH,-1.17833,0.0500837,0.00492501,0.902365 beta-lactamase_0_K53L,beta-lactamase_0_53,TEM-1,beta-lactamase_0,P62593,0.902399,NO,53,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-2.313,-2.678,0.365,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.0500837,0.00383383,0.902399 beta-lactamase_F17N,beta-lactamase_17,TEM-1,beta-lactamase,P62593,0.902427,NO,17,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-2.337,-3.99,1.653,,,,,,,2.192,,67.83,HHO,-2.17733,0.221079,0.00216499,0.902427 kka2_1:8_A129P,kka2_1:8_129,Kka2,kka2_1:8,P00552,0.902494,NO,129,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.656,-4.009,2.353,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.100394,0.00726862,0.902494 kka2_1:8_A129P,kka2_1:8_129,Kka2,kka2_1:8,P00552,0.902494,NO,129,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.656,-4.009,2.353,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.100394,0.00726862,0.902494 beta-lactamase_0_E175P,beta-lactamase_0_175,TEM-1,beta-lactamase_0,P62593,0.902495,NO,175,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.336,-1.972,-0.364,,0.551,,A,1.04,1.05,2.334,,77.62,AAB,-1.31233,0.0500837,0.00482205,0.902495 beta-lactamase_L28R,beta-lactamase_28,TEM-1,beta-lactamase,P62593,0.902512,NO,28,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.579,-2.903,1.324,5.42969,0.277,H,A,0.07,-0.16,19.748,19.748,93.01,PHH,-2.11333,0.221079,0.00359321,0.902512 kka2_1:4_V153Q,kka2_1:4_153,Kka2,kka2_1:4,P00552,0.902529,NO,153,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.092,-4.272,3.18,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.168804,0.00501119,0.902529 kka2_1:4_Q27E,kka2_1:4_27,Kka2,kka2_1:4,P00552,0.902581,NO,27,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-1.659,-2.681,1.022,,0.608,,A,0.4,0.71,1.498,,65.53,PPP,-1.90733,0.168804,0.00595365,0.902581 Pab1_Y197C,Pab1_197,Pab1,Pab1,P04147,0.902584,NO,197,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-1.345,-4.775,3.43,,,,,,,0.891,,80.42,HHH,-1.41767,0.175299,0.00302474,0.902584 beta-lactamase_V106H,beta-lactamase_106,TEM-1,beta-lactamase,P62593,0.90259,NO,106,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.218,-4.937,3.719,5.23115,0.258,T,A,0.96,0.24,1.188,,72.73,OHP,-1.04933,0.221079,0.00304168,0.90259 kka2_1:4_P12I,kka2_1:4_12,Kka2,kka2_1:4,P00552,0.902601,NO,12,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.853,-3.96,3.107,,,,B,0.52,1.25,0.843,,48.11,POH,-1.80767,0.168804,0.00500011,0.902601 beta-lactamase_2500_R41A,beta-lactamase_2500_41,TEM-1,beta-lactamase_2500,P62593,0.902605,NO,41,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-0.942,-3.041,2.099,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.361275,0.00123327,0.902605 PSD95pdz3_S339Y,PSD95pdz3_339,PSD95pdz3,PSD95pdz3,P31016,0.902605,NO,339,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.519,-3.844,2.325,5.34493,,,,,12.2167,,,,HPH,-1.55767,0.0758425,0.00084982,0.902605 beta-lactamase_156_I45R,beta-lactamase_156_45,TEM-1,beta-lactamase_156,P62593,0.902637,NO,45,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-2.421,-4.043,1.622,,,E,B,0.48,-0.3,2.256,,77.62,HHA,-2.30267,0.111618,0.00452842,0.902637 beta-lactamase_H5V,beta-lactamase_5,TEM-1,beta-lactamase,P62593,0.90266,NO,5,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-2.698,-3.375,0.677,,,,,,,1.865,,72.73,PBH,-2.36967,0.221079,0.00292712,0.90266 PSD95pdz3_G351Y,PSD95pdz3_351,PSD95pdz3,PSD95pdz3,P31016,0.902662,NO,351,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.008,-4.069,3.061,5.44798,,,,,20.7625,,,,POA,-1.37133,0.0758425,0.000691282,0.902662 kka2_1:4_W24H,kka2_1:4_24,Kka2,kka2_1:4,P00552,0.902679,NO,24,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-1.779,-4.882,3.103,,0.477,E,B,1.51,-0.21,2.666,,56.06,AHH,-2.24467,0.168804,0.00631564,0.902679 kka2_1:2_D156W,kka2_1:2_156,Kka2,kka2_1:2,P00552,0.902688,NO,156,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.696,-5.547,3.851,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.295029,0.00926998,0.902688 kka2_1:2_H124Q,kka2_1:2_124,Kka2,kka2_1:2,P00552,0.902698,NO,124,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-0.84,-3.703,2.863,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.295029,0.00211296,0.902698 beta-lactamase_A170T,beta-lactamase_170,TEM-1,beta-lactamase,P62593,0.902716,NO,170,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.237,-3.423,2.186,5.19261,0.126,,L,2.34,-0.35,2.427,,64.69,AHH,-1.63267,0.221079,0.00431903,0.902716 beta-lactamase_G216D,beta-lactamase_216,TEM-1,beta-lactamase,P62593,0.902725,NO,216,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.477,-1.722,0.245,4.91694,0.437,I,A,0.23,-0.58,1.718,,74.48,HOO,-1.68067,0.221079,0.00639568,0.902725 kka2_1:4_V36G,kka2_1:4_36,Kka2,kka2_1:4,P00552,0.902776,NO,36,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-0.898,-3.694,2.796,,0.292,E,B,0.44,0.21,0.278,,52.27,HHH,-1.484,0.168804,0.00245633,0.902776 kka2_1:8_L67M,kka2_1:8_67,Kka2,kka2_1:8,P00552,0.902782,NO,67,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.741,-3.833,3.092,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.100394,0.00102787,0.902782 kka2_1:8_L67M,kka2_1:8_67,Kka2,kka2_1:8,P00552,0.902782,NO,67,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.741,-3.833,3.092,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.100394,0.00102787,0.902782 beta-lactamase_0_I277D,beta-lactamase_0_277,TEM-1,beta-lactamase_0,P62593,0.902791,NO,277,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.0500837,0.0169305,0.902791 beta-lactamase_2500_T264I,beta-lactamase_2500_264,TEM-1,beta-lactamase_2500,P62593,0.902874,NO,264,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.361275,0.0119399,0.902874 beta-lactamase_R189D,beta-lactamase_189,TEM-1,beta-lactamase,P62593,0.902876,NO,189,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.844,-2.871,1.027,5.74877,0.278,H,A,0.68,1.01,1.512,,72.73,HBB,-1.668,0.221079,0.0050699,0.902876 beta-lactamase_2500_R59H,beta-lactamase_2500_59,TEM-1,beta-lactamase_2500,P62593,0.902885,NO,59,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.345,-4.424,3.079,,0.329,S,L,1.2,-0.09,3.719,,73.08,HBO,-2.24267,0.361275,0.00318082,0.902885 kka2_1:2_G21R,kka2_1:2_21,Kka2,kka2_1:2,P00552,0.902885,NO,21,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.368,-3.948,2.58,,0.586,T,l,0.29,-0.75,2.026,,71.59,HOH,-2.10167,0.295029,0.00709648,0.902885 beta-lactamase_0_N152G,beta-lactamase_0_152,TEM-1,beta-lactamase_0,P62593,0.9029,NO,152,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-2.757,-2.26,-0.497,,0.863,H,A,0.61,0.92,2.151,,77.62,BPH,-2.97,0.0500837,0.00471429,0.9029 kka2_1:8_A129E,kka2_1:8_129,Kka2,kka2_1:8,P00552,0.902958,NO,129,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.656,-2.346,0.69,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.100394,0.00726862,0.902958 kka2_1:8_A129E,kka2_1:8_129,Kka2,kka2_1:8,P00552,0.902958,NO,129,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.656,-2.346,0.69,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.100394,0.00726862,0.902958 beta-lactamase_E87F,beta-lactamase_87,TEM-1,beta-lactamase,P62593,0.902978,NO,87,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.421,-4.277,2.856,5.41929,0.048,,B,0.52,0.92,1.754,,64.69,PAP,-1.969,0.221079,0.00337888,0.902978 beta-lactamase_0_M184H,beta-lactamase_0_184,TEM-1,beta-lactamase_0,P62593,0.902992,NO,184,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.593,-4.818,3.225,,,H,A,0.55,-0.87,13.292,13.292,62.94,HHH,-1.41,0.0500837,0.00356019,0.902992 beta-lactamase_G85L,beta-lactamase_85,TEM-1,beta-lactamase,P62593,0.903018,NO,85,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.011,-3.755,2.744,5.58951,0.805,T,l,0.23,1.7,1.468,,63.64,HOP,-1.68733,0.221079,0.00252173,0.903018 kka2_1:8_D250M,kka2_1:8_250,Kka2,kka2_1:8,P00552,0.903033,NO,250,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.015,-4.907,3.892,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.100394,0.0177103,0.903033 kka2_1:8_D250M,kka2_1:8_250,Kka2,kka2_1:8,P00552,0.903033,NO,250,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.015,-4.907,3.892,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.100394,0.0177103,0.903033 WW_domain_S183E,WW_domain_183,Yap65,WW_domain,P46937,0.90304,NO,183,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.95,-3.326,1.376,5.35576,,,,,,1.594,,83.93,PPP,-1.48733,0.153962,0.00445513,0.90304 hsp90_G584S,hsp90_584,hsp90,hsp90,P02829,0.903061,NO,584,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-2.511,-2.764,0,5.20094,0.414,S,b,0.84,0.33,,,,HOH,-3.32733,0.368192,0.000222939,0.903061 beta-lactamase_0_A225W,beta-lactamase_0_225,TEM-1,beta-lactamase_0,P62593,0.903078,NO,225,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.845,-5.541,3.696,,1,T,B,0.46,-0.38,11.722,11.722,74.48,OHO,-1.39967,0.0500837,0.00465057,0.903078 beta-lactamase_I283A,beta-lactamase_283,TEM-1,beta-lactamase,P62593,0.90309,NO,283,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.638,-2.465,0.827,5.4178,0.165,H,A,1.23,0.04,1.576,,69.23,HHB,-1.735,0.221079,0.0429138,0.90309 beta-lactamase_0_P224R,beta-lactamase_0_224,TEM-1,beta-lactamase_0,P62593,0.903096,NO,224,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.893,-2.763,1.87,,0.383,,B,0.52,-0.3,3.587,,74.48,HOH,-1.26433,0.0500837,0.00189564,0.903096 beta-lactamase_0_V78A,beta-lactamase_0_78,TEM-1,beta-lactamase_0,P62593,0.903096,NO,78,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.459,-3.121,1.662,,,H,A,0.44,-0.47,16.615,16.615,63.64,HHH,-1.17833,0.0500837,0.00492501,0.903096 beta-lactamase_625_W208D,beta-lactamase_625_208,TEM-1,beta-lactamase_625,P62593,0.9031,NO,208,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-0.818,-4.144,3.326,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.213352,0.00126609,0.9031 beta-lactamase_0_Q276A,beta-lactamase_0_276,TEM-1,beta-lactamase_0,P62593,0.90313,NO,276,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-1.144,-3.872,2.728,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.0500837,0.0191712,0.90313 beta-lactamase_0_S104E,beta-lactamase_0_104,TEM-1,beta-lactamase_0,P62593,0.903135,NO,104,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.015,-3.366,2.351,,0.04,,b,0.27,0.57,1.148,,63.29,HPO,-1.05267,0.0500837,0.00218083,0.903135 PSD95pdz3_V362I,PSD95pdz3_362,PSD95pdz3,PSD95pdz3,P31016,0.903135,NO,362,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.465,-2.342,0.877,4.99436,,,,,19.6443,,,,PHP,-1.46467,0.0758425,0.000538527,0.903135 beta-lactamase_625_G76L,beta-lactamase_625_76,TEM-1,beta-lactamase_625,P62593,0.903161,NO,76,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.189,-3.521,2.332,,,H,A,0.29,-0.67,3.059,,67.83,OOH,-1.22267,0.213352,0.00476637,0.903161 beta-lactamase_N50C,beta-lactamase_50,TEM-1,beta-lactamase,P62593,0.903183,NO,50,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-2.979,-5.044,2.065,5.51261,0.912,T,A,1.07,1.24,1.581,,77.62,HPP,-2.134,0.221079,0.0047211,0.903183 beta-lactamase_R176A,beta-lactamase_176,TEM-1,beta-lactamase,P62593,0.903211,NO,176,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-0.863,-3.078,2.215,5.61264,0.385,T,B,0.68,-0.63,,,,ABA,-1.38867,0.221079,0.00105554,0.903211 beta-lactamase_S104A,beta-lactamase_104,TEM-1,beta-lactamase,P62593,0.903211,NO,104,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.015,-2.043,1.028,4.92365,0.04,,b,0.82,0.57,4.02,,63.29,HPO,-1.05267,0.221079,0.00218083,0.903211 beta-lactamase_156_S122P,beta-lactamase_156_122,TEM-1,beta-lactamase_156,P62593,0.903219,NO,122,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.406,-4.011,1.605,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.111618,0.00497825,0.903219 kka2_1:8_A150S,kka2_1:8_150,Kka2,kka2_1:8,P00552,0.903223,NO,150,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.949,-3.097,2.148,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.100394,0.0045009,0.903223 kka2_1:8_A150S,kka2_1:8_150,Kka2,kka2_1:8,P00552,0.903223,NO,150,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.949,-3.097,2.148,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.100394,0.0045009,0.903223 Ubiquitin_D24L,Ubiquitin_24,Uba1,Ubiquitin,P0CG48,0.903226,NO,24,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,,,,,,,,,,,,,HAP,,0.205827,0.0066591,0.903226 Ubiquitin_D32M,Ubiquitin_32,Uba1,Ubiquitin,P0CG48,0.903226,NO,32,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.451,-4.784,3.333,4.96502,0.835,H,A,,1.4,,,,PAB,-1.47067,0.205827,0.000758819,0.903226 Ubiquitin_D58S,Ubiquitin_58,Uba1,Ubiquitin,P0CG48,0.903226,NO,58,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.622,-2.745,1.123,5.06391,0.457,G,A,,-0.54,,,,PAH,-1.60267,0.205827,0.000639847,0.903226 Ubiquitin_E64D,Ubiquitin_64,Uba1,Ubiquitin,P0CG48,0.903226,NO,64,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.763,-2.574,0.811,5.084,0.54,T,l,,0.79,,,,BAP,-1.64433,0.205827,0.000817406,0.903226 Ubiquitin_K33F,Ubiquitin_33,Uba1,Ubiquitin,P0CG48,0.903226,NO,33,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.283,-4.091,2.808,5.08526,0.64,H,A,1.82,1.2,1.509,,51.09,ABA,-1.34267,0.205827,0.000712743,0.903226 Ubiquitin_K33W,Ubiquitin_33,Uba1,Ubiquitin,P0CG48,0.903226,NO,33,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.283,-5.309,4.026,5.08526,0.64,H,A,1.82,1.2,1.509,,51.09,ABA,-1.34267,0.205827,0.000712743,0.903226 Ubiquitin_K6A,Ubiquitin_6,Uba1,Ubiquitin,P0CG48,0.903226,NO,6,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.093,-3.091,1.998,4.84211,0.35,E,B,1.82,-0.62,1.502,,71.82,HBP,-1.36133,0.205827,0.000784795,0.903226 Ubiquitin_K6H,Ubiquitin_6,Uba1,Ubiquitin,P0CG48,0.903226,NO,6,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.093,-4.395,3.302,4.84211,0.35,E,B,1.82,-0.62,1.502,,71.82,HBP,-1.36133,0.205827,0.000784795,0.903226 Ubiquitin_K6T,Ubiquitin_6,Uba1,Ubiquitin,P0CG48,0.903226,NO,6,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.093,-3.435,2.342,4.84211,0.35,E,B,1.82,-0.62,1.502,,71.82,HBP,-1.36133,0.205827,0.000784795,0.903226 Ubiquitin_K6V,Ubiquitin_6,Uba1,Ubiquitin,P0CG48,0.903226,NO,6,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.093,-3.566,2.473,4.84211,0.35,E,B,1.82,-0.62,1.502,,71.82,HBP,-1.36133,0.205827,0.000784795,0.903226 Ubiquitin_P37F,Ubiquitin_37,Uba1,Ubiquitin,P0CG48,0.903226,NO,37,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.275,-4.269,2.994,5.06918,0.323,,B,,-0.09,,,,HOO,-1.49,0.205827,0.000600764,0.903226 Ubiquitin_P37Y,Ubiquitin_37,Uba1,Ubiquitin,P0CG48,0.903226,NO,37,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.275,-4.197,2.922,5.06918,0.323,,B,,-0.09,,,,HOO,-1.49,0.205827,0.000600764,0.903226 Ubiquitin_T55W,Ubiquitin_55,Uba1,Ubiquitin,P0CG48,0.903226,NO,55,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.599,-5.25,3.651,4.58329,0.173,B,B,,-0.68,,,,BPH,-1.65333,0.205827,0.000525703,0.903226 Ubiquitin_T9I,Ubiquitin_9,Uba1,Ubiquitin,P0CG48,0.903226,NO,9,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.409,-3.597,2.188,5.24336,0.777,T,A,2.12,-0.12,2.705,,29.93,HPO,-1.50933,0.205827,0.000630716,0.903226 PSD95pdz3_Y392I,PSD95pdz3_392,PSD95pdz3,PSD95pdz3,P31016,0.903235,NO,392,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-1.437,-3.242,1.805,5.20337,,,,,11.725,,,,PHB,-1.51733,0.0758425,0.000935211,0.903235 beta-lactamase_0_P165C,beta-lactamase_0_165,TEM-1,beta-lactamase_0,P62593,0.903267,NO,165,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.373,-4.892,3.519,,0.203,T,A,0.52,-0.31,3.242,,73.78,AOA,-1.359,0.0500837,0.00549538,0.903267 kka2_1:4_M197C,kka2_1:4_197,Kka2,kka2_1:4,P00552,0.903297,NO,197,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.707,-4.828,3.121,,0.121,E,B,0.55,-1.19,0.415,,65.53,HHH,-1.847,0.168804,0.00921295,0.903297 Pab1_D184P,Pab1_184,Pab1,Pab1,P04147,0.903319,NO,184,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.5,-3.543,2.043,,,,,,,,,,HAH,-1.50133,0.175299,0.0011931,0.903319 beta-lactamase_2500_E210G,beta-lactamase_2500_210,TEM-1,beta-lactamase_2500,P62593,0.903325,NO,210,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.319,-3.66,1.341,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.361275,0.00663582,0.903325 kka2_1:1_A168S,kka2_1:1_168,Kka2,kka2_1:1,P00552,0.903398,NO,168,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.989,-2.65,0.661,,0.67,H,A,0.46,0.15,25.546,25.546,64.39,OHA,-2.12933,0.520039,0.00806773,0.903398 beta-lactamase_0_W163M,beta-lactamase_0_163,TEM-1,beta-lactamase_0,P62593,0.903427,NO,163,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-1.843,-3.104,1.261,,0.467,,B,0.47,-0.5,13.843,13.843,63.99,BHA,-1.269,0.0500837,0.00418955,0.903427 beta-lactamase_156_T147F,beta-lactamase_156_147,TEM-1,beta-lactamase_156,P62593,0.903441,NO,147,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.149,-4.147,2.998,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.111618,0.00226017,0.903441 kka2_1:8_G245R,kka2_1:8_245,Kka2,kka2_1:8,P00552,0.903466,NO,245,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.812,-3.916,3.104,,0.655,T,g,0.75,0.03,1.148,,65.53,HOH,-1.19833,0.100394,0.00683899,0.903466 kka2_1:8_G245R,kka2_1:8_245,Kka2,kka2_1:8,P00552,0.903466,NO,245,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.812,-3.916,3.104,,0.655,T,g,0.75,0.03,1.148,,65.53,HOH,-1.19833,0.100394,0.00683899,0.903466 beta-lactamase_0_P143A,beta-lactamase_0_143,TEM-1,beta-lactamase_0,P62593,0.903469,NO,143,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.967,-3.126,2.159,,0.075,H,A,0.52,-0.37,11.868,11.868,66.78,OOB,-1.354,0.0500837,0.00114551,0.903469 kka2_1:1_L243R,kka2_1:1_243,Kka2,kka2_1:1,P00552,0.903483,NO,243,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-2.651,-2.013,-0.638,,0.277,H,A,0.55,-0.67,4.334,,92.05,HHH,-2.03767,0.520039,0.00884927,0.903483 kka2_1:4_C209M,kka2_1:4_209,Kka2,kka2_1:4,P00552,0.903541,NO,209,C,M,CM,Special,Hydrophobic,5.07,5.74,0.67,196,121,149,28,108.5,162.9,54.4,-0.906,-4.438,3.532,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.168804,0.00260862,0.903541 beta-lactamase_0_R81C,beta-lactamase_0_81,TEM-1,beta-lactamase_0,P62593,0.90357,NO,81,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.466,-5.147,3.681,,0.218,H,A,1.2,1.66,0.332,,50,PBH,-1.60667,0.0500837,0.00499763,0.90357 Pab1_K156R,Pab1_156,Pab1,Pab1,P04147,0.903652,NO,156,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.083,-2.85,1.767,,0.406,E,B,1.82,-0.26,,,,PBH,-1.58167,0.175299,0.000316767,0.903652 kka2_1:4_T28W,kka2_1:4_28,Kka2,kka2_1:4,P00552,0.903729,NO,28,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.883,-5.518,3.635,,0.353,S,B,0.82,2.02,4.415,,63.64,PPH,-1.74467,0.168804,0.00743084,0.903729 WW_domain_S183P,WW_domain_183,Yap65,WW_domain,P46937,0.903752,NO,183,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.95,-2.199,0.249,5.35576,,,,,,1.594,,83.93,PPP,-1.48733,0.153962,0.00445513,0.903752 beta-lactamase_625_P165Y,beta-lactamase_625_165,TEM-1,beta-lactamase_625,P62593,0.90376,NO,165,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.373,-4.331,2.958,,0.203,T,A,0.52,-0.31,0.414,,73.78,AOA,-1.359,0.213352,0.00549538,0.90376 beta-lactamase_156_R220D,beta-lactamase_156_220,TEM-1,beta-lactamase_156,P62593,0.903764,NO,220,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-0.942,-3.72,2.778,,0.295,I,A,1.2,-0.76,2.164,,74.48,HBP,-1.33633,0.111618,0.00232421,0.903764 beta-lactamase_2500_W163E,beta-lactamase_2500_163,TEM-1,beta-lactamase_2500,P62593,0.903769,NO,163,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-1.843,-3.693,1.85,,0.467,,B,0.47,-0.5,32.624,32.624,63.99,BHA,-1.269,0.361275,0.00418955,0.903769 beta-lactamase_V42C,beta-lactamase_42,TEM-1,beta-lactamase,P62593,0.903771,NO,42,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.564,-4.789,3.225,5.27904,0.017,E,B,1.64,-0.51,2.024,,63.99,BHO,-1.042,0.221079,0.00404515,0.903771 beta-lactamase_0_M184W,beta-lactamase_0_184,TEM-1,beta-lactamase_0,P62593,0.903836,NO,184,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.593,-5.149,3.556,,,H,A,0.55,-0.87,13.292,13.292,62.94,HHH,-1.41,0.0500837,0.00356019,0.903836 beta-lactamase_2500_Q203Y,beta-lactamase_2500_203,TEM-1,beta-lactamase_2500,P62593,0.903947,NO,203,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.168,-4.35,2.182,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.361275,0.00631514,0.903947 PSD95pdz3_Y392P,PSD95pdz3_392,PSD95pdz3,PSD95pdz3,P31016,0.904008,NO,392,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-1.437,-3.786,2.349,5.20337,,,,,11.725,,,,PHB,-1.51733,0.0758425,0.000935211,0.904008 beta-lactamase_0_I54N,beta-lactamase_0_54,TEM-1,beta-lactamase_0,P62593,0.904036,NO,54,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-2.838,-2.849,0.011,,0.669,E,B,0.48,-0.14,0.541,,73.78,BHH,-2.337,0.0500837,0.00403589,0.904036 kka2_1:1_T146M,kka2_1:1_146,Kka2,kka2_1:1,P00552,0.904042,NO,146,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.978,-3.5,0.522,,0.281,H,A,0.82,0.78,2.105,,92.05,BPB,-1.96833,0.520039,0.00606474,0.904042 gb1_T281I,gb1_281,gb1,gb1,P06654,0.904094,NO,281,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.828,-3.583,1.755,,,,,,,1.038,,35.71,HPA,-1.63667,0.177985,0.00284418,0.904094 Pab1_Y197H,Pab1_197,Pab1,Pab1,P04147,0.904094,NO,197,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-1.345,-3.907,2.562,,,,,,,0.891,,80.42,HHH,-1.41767,0.175299,0.00302474,0.904094 beta-lactamase_0_S283P,beta-lactamase_0_283,TEM-1,beta-lactamase_0,P62593,0.904097,NO,283,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.0500837,0.0429138,0.904097 beta-lactamase_39_C121N,beta-lactamase_39_121,TEM-1,beta-lactamase_39,P62593,0.904099,NO,121,C,N,CN,Special,Polar,5.07,5.47157,0.401575,139,121,132,11,108.5,114.1,5.6,-0.953,-4.045,3.092,,,H,A,0.46,-0.81,7.644,,63.29,HOP,-1.46767,0.0495842,0.000744322,0.904099 beta-lactamase_39_A211P,beta-lactamase_39_211,TEM-1,beta-lactamase_39,P62593,0.904129,NO,211,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.896,-3.94,2.044,,0.369,T,A,0.46,-0.69,1.419,,77.62,AHA,-1.94633,0.0495842,0.00648183,0.904129 beta-lactamase_E195V,beta-lactamase_195,TEM-1,beta-lactamase,P62593,0.904141,NO,195,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.186,-3.798,1.612,7.28489,1.016,S,A,1.52,0.85,2.583,,77.62,OAH,-2.02,0.221079,0.00496565,0.904141 beta-lactamase_E270N,beta-lactamase_270,TEM-1,beta-lactamase,P62593,0.904141,NO,270,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.723,-3.691,1.968,5.33196,0.422,H,A,0.52,1.15,1.745,,64.34,AAB,-1.70933,0.221079,0.00767762,0.904141 beta-lactamase_E277H,beta-lactamase_277,TEM-1,beta-lactamase,P62593,0.904141,NO,277,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.869,-4.668,2.799,5.51786,0.545,H,A,0.52,-0.01,2.022,,77.62,HAH,-1.45367,0.221079,0.0169305,0.904141 beta-lactamase_E56H,beta-lactamase_56,TEM-1,beta-lactamase,P62593,0.904141,NO,56,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.043,-4.467,2.424,5.65281,0.198,E,B,0.52,0.31,2.022,,72.73,HAP,-1.94033,0.221079,0.00238534,0.904141 beta-lactamase_F58C,beta-lactamase_58,TEM-1,beta-lactamase,P62593,0.904141,NO,58,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-2.914,-5.093,2.179,5.55634,0.266,E,B,1.33,-0.07,2.467,,77.62,PHB,-2.059,0.221079,0.00523369,0.904141 beta-lactamase_H110N,beta-lactamase_110,TEM-1,beta-lactamase,P62593,0.904141,NO,110,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-1.706,-3.626,1.92,5.52635,0.341,G,a,0.35,1.08,31.31,31.31,64.69,BBH,-1.73333,0.221079,0.00441499,0.904141 beta-lactamase_S51A,beta-lactamase_51,TEM-1,beta-lactamase,P62593,0.904141,NO,51,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.526,-2.32,0.794,5.06164,0.496,T,A,0.25,0.26,1.699,,72.73,PPO,-1.88467,0.221079,0.00504821,0.904141 beta-lactamase_T131C,beta-lactamase_131,TEM-1,beta-lactamase,P62593,0.904141,NO,131,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.328,-3.123,1.795,5.0548,,H,A,0.53,-0.69,3.306,,67.48,PPH,-1.00867,0.221079,0.00345886,0.904141 beta-lactamase_V101R,beta-lactamase_101,TEM-1,beta-lactamase,P62593,0.904141,NO,101,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.295,-4.134,2.839,5.49045,0.342,,B,0.96,0,1.675,,73.08,HHA,-1.54367,0.221079,0.00374492,0.904141 beta-lactamase_V214K,beta-lactamase_214,TEM-1,beta-lactamase,P62593,0.904141,NO,214,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.299,-3.699,2.4,5.74008,0.375,S,A,1.19,-0.44,1.899,,74.48,BHH,-1.53733,0.221079,0.00628442,0.904141 beta-lactamase_W227F,beta-lactamase_227,TEM-1,beta-lactamase,P62593,0.904141,NO,227,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-0.982,-2.609,1.627,4.86393,0.272,,B,0.99,-0.29,1.37,,74.48,OHH,-1.595,0.221079,0.00226019,0.904141 kka2_1:8_A137S,kka2_1:8_137,Kka2,kka2_1:8,P00552,0.90417,NO,137,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.156,-2.895,0.739,,0.029,H,A,1.04,0.34,2.886,,63.26,PHB,-2.559,0.100394,0.00515054,0.90417 kka2_1:8_A137S,kka2_1:8_137,Kka2,kka2_1:8,P00552,0.90417,NO,137,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.156,-2.895,0.739,,0.029,H,A,1.04,0.34,2.886,,63.26,PHB,-2.559,0.100394,0.00515054,0.90417 kka2_1:4_V153P,kka2_1:4_153,Kka2,kka2_1:4,P00552,0.904201,NO,153,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.092,-4.027,2.935,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.168804,0.00501119,0.904201 beta-lactamase_0_L167W,beta-lactamase_0_167,TEM-1,beta-lactamase_0,P62593,0.904242,NO,167,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.138,-5.22,4.082,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.0500837,0.00303566,0.904242 kka2_1:4_N195D,kka2_1:4_195,Kka2,kka2_1:4,P00552,0.904251,NO,195,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-0.836,-2.379,1.543,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.168804,0.00276134,0.904251 beta-lactamase_625_L74C,beta-lactamase_625_74,TEM-1,beta-lactamase_625,P62593,0.904257,NO,74,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.296,-4.647,3.351,,,H,A,0.55,-0.91,0.895,,50,HHO,-1.34933,0.213352,0.00493255,0.904257 kka2_1:8_V113C,kka2_1:8_113,Kka2,kka2_1:8,P00552,0.904258,NO,113,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.233,-4.781,3.548,,0.008,H,A,1.48,-1.17,1.254,,52.27,BHP,-2.08367,0.100394,0.00650191,0.904258 kka2_1:8_V113C,kka2_1:8_113,Kka2,kka2_1:8,P00552,0.904258,NO,113,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.233,-4.781,3.548,,0.008,H,A,1.48,-1.17,1.254,,52.27,BHP,-2.08367,0.100394,0.00650191,0.904258 beta-lactamase_39_L223D,beta-lactamase_39_223,TEM-1,beta-lactamase_39,P62593,0.904295,NO,223,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.055,-4.067,3.012,,0.27,,B,0.55,0.09,1.511,,74.48,HHO,-1.35033,0.0495842,0.00372793,0.904295 beta-lactamase_2500_R273V,beta-lactamase_2500_273,TEM-1,beta-lactamase_2500,P62593,0.904296,NO,273,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.314,-3.626,1.312,,0.564,H,A,1.2,1.57,19.943,19.943,73.78,ABP,-1.841,0.361275,0.0077952,0.904296 beta-lactamase_0_R273V,beta-lactamase_0_273,TEM-1,beta-lactamase_0,P62593,0.904305,NO,273,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.314,-3.626,1.312,,0.564,H,A,1.2,1.57,20.248,20.248,73.78,ABP,-1.841,0.0500837,0.0077952,0.904305 beta-lactamase_0_R159T,beta-lactamase_0_159,TEM-1,beta-lactamase_0,P62593,0.904306,NO,159,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-0.94,-3.47,2.53,,0.316,,B,1.2,-0.55,1.426,,64.34,PBH,-1.011,0.0500837,0.00108472,0.904306 beta-lactamase_0_L79K,beta-lactamase_0_79,TEM-1,beta-lactamase_0,P62593,0.904314,NO,79,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.842,-3.679,2.837,,0.007,H,A,0.55,-0.16,5.053,,50.35,HHP,-1.44333,0.0500837,0.000947397,0.904314 beta-lactamase_0_L79A,beta-lactamase_0_79,TEM-1,beta-lactamase_0,P62593,0.904348,NO,79,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.842,-3.103,2.261,,0.007,H,A,0.55,-0.16,5.053,,50.35,HHP,-1.44333,0.0500837,0.000947397,0.904348 beta-lactamase_39_G249D,beta-lactamase_39_249,TEM-1,beta-lactamase_39,P62593,0.904385,NO,249,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.312,,,,0.256,S,B,0.23,0.04,30.841,30.841,72.73,HOO,-1.81367,0.0495842,0.00220169,0.904385 kka2_1:4_H124Q,kka2_1:4_124,Kka2,kka2_1:4,P00552,0.904411,NO,124,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-0.84,-3.703,2.863,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.168804,0.00211296,0.904411 beta-lactamase_T262A,beta-lactamase_262,TEM-1,beta-lactamase,P62593,0.904446,NO,262,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.332,-2.195,0.863,5.06002,0.108,E,B,0.3,-0.55,1.423,,67.83,PPO,-2.081,0.221079,0.00853516,0.904446 beta-lactamase_0_H287C,beta-lactamase_0_287,TEM-1,beta-lactamase_0,P62593,0.904515,NO,287,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,,,,,,,,,,,,,BBH,-1.111,0.0500837,,0.904515 kka2_1:4_H106L,kka2_1:4_106,Kka2,kka2_1:4,P00552,0.90454,NO,106,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-3.13,-2.804,-0.326,,1.065,.,a,0.17,-0.95,16.74,16.74,71.59,PBH,-2.10433,0.168804,0.00730778,0.90454 kka2_1:1_I29L,kka2_1:1_29,Kka2,kka2_1:1,P00552,0.90455,NO,29,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.692,-1.88,0.188,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.520039,0.00619521,0.90455 beta-lactamase_0_V29Q,beta-lactamase_0_29,TEM-1,beta-lactamase_0,P62593,0.904616,NO,29,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-2.856,-2.926,0.07,,0.733,H,A,0.44,-0.78,21.916,21.916,93.01,HHB,-2.24733,0.0500837,0.00318969,0.904616 Pab1_V148Q,Pab1_148,Pab1,Pab1,P04147,0.904623,NO,148,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.875,-3.898,2.023,,,,,,,,,,PHH,-1.43033,0.175299,0.00179641,0.904623 beta-lactamase_A40T,beta-lactamase_40,TEM-1,beta-lactamase,P62593,0.904642,NO,40,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.402,-2.653,1.251,4.9697,0.155,S,B,1.2,0.21,1.714,,73.78,OHB,-1.40267,0.221079,0.00490026,0.904642 beta-lactamase_0_A124F,beta-lactamase_0_124,TEM-1,beta-lactamase_0,P62593,0.904661,NO,124,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.181,-4.133,2.952,,,H,A,0.46,-0.9,1.876,,64.34,HHH,-1.152,0.0500837,0.00481399,0.904661 kka2_1:4_E169S,kka2_1:4_169,Kka2,kka2_1:4,P00552,0.904768,NO,169,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.996,-2.626,0.63,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.168804,0.00730086,0.904768 beta-lactamase_2500_Q86C,beta-lactamase_2500_86,TEM-1,beta-lactamase_2500,P62593,0.904772,NO,86,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.4,-5.132,2.732,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.361275,0.00450027,0.904772 beta-lactamase_S2A,beta-lactamase_2,TEM-1,beta-lactamase,P62593,0.904834,NO,2,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.942,-2.747,0.805,,,,,,,2.36,,65.38,HPH,-2.02767,0.221079,0.00227352,0.904834 kka2_1:2_P194R,kka2_1:2_194,Kka2,kka2_1:2,P00552,0.904884,NO,194,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.846,-3.983,3.137,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.295029,0.00314194,0.904884 beta-lactamase_625_R257V,beta-lactamase_625_257,TEM-1,beta-lactamase_625,P62593,0.904895,NO,257,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.533,-4.11,2.577,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.213352,0.00756629,0.904895 beta-lactamase_0_L111K,beta-lactamase_0_111,TEM-1,beta-lactamase_0,P62593,0.904897,NO,111,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.76,-3.773,2.013,,0.328,T,A,0.55,0.93,1.966,,64.34,BHP,-1.884,0.0500837,0.00480671,0.904897 beta-lactamase_P12K,beta-lactamase_12,TEM-1,beta-lactamase,P62593,0.904936,NO,12,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-2.016,-3.588,1.572,,,,,,,2.88,,72.73,HOH,-2.05167,0.221079,0.00241653,0.904936 beta-lactamase_Q4P,beta-lactamase_4,TEM-1,beta-lactamase,P62593,0.904936,NO,4,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,,-3.752,1.188,,,,,,,,,,HPB,,0.221079,0.00316562,0.904936 beta-lactamase_0_L199A,beta-lactamase_0_199,TEM-1,beta-lactamase_0,P62593,0.904938,NO,199,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-2.942,-2.055,-0.887,,0.832,H,A,0.55,0.42,10.85,10.85,77.62,PHH,-2.32933,0.0500837,0.0048649,0.904938 beta-lactamase_2500_R81H,beta-lactamase_2500_81,TEM-1,beta-lactamase_2500,P62593,0.904938,NO,81,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.466,-4.464,2.998,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.361275,0.00499763,0.904938 gb1_K239D,gb1_239,gb1,gb1,P06654,0.904967,NO,239,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-3.043,-2.936,-0.107,,,,,,,1.326,,45.54,HBO,-2.31467,0.177985,0.00207004,0.904967 beta-lactamase_0_L49S,beta-lactamase_0_49,TEM-1,beta-lactamase_0,P62593,0.90498,NO,49,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.897,-2.417,0.52,,0.131,T,A,0.55,0.04,13.838,13.838,64.69,AHP,-1.99233,0.0500837,0.00401477,0.90498 beta-lactamase_R162G,beta-lactamase_162,TEM-1,beta-lactamase,P62593,0.904999,NO,162,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.016,-3.445,2.429,5.34456,0.124,S,B,0.68,-0.37,31.656,31.656,64.69,ABH,-1.25,0.221079,0.000561334,0.904999 PSD95pdz3_D357N,PSD95pdz3_357,PSD95pdz3,PSD95pdz3,P31016,0.905005,NO,357,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.264,-2.905,1.641,5.22306,,,,,10.975,,,,OAP,-1.32367,0.0758425,0.000609015,0.905005 beta-lactamase_2500_D113W,beta-lactamase_2500_113,TEM-1,beta-lactamase_2500,P62593,0.905071,NO,113,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.829,-5.545,3.716,,0.665,T,A,0.75,0.91,21.104,21.104,73.08,PAO,-1.703,0.361275,0.00474112,0.905071 beta-lactamase_A15H,beta-lactamase_15,TEM-1,beta-lactamase,P62593,0.905072,NO,15,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.654,-4.672,3.018,,,,,,,31.998,31.998,93.01,HHH,-2.10833,0.221079,0.00248966,0.905072 beta-lactamase_H110C,beta-lactamase_110,TEM-1,beta-lactamase,P62593,0.905072,NO,110,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-1.706,-5.217,3.511,5.52635,0.341,G,a,0.35,1.08,31.31,31.31,64.69,BBH,-1.73333,0.221079,0.00441499,0.905072 beta-lactamase_R92E,beta-lactamase_92,TEM-1,beta-lactamase,P62593,0.905072,NO,92,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.718,-2.624,0.906,5.65832,0.479,E,B,0.91,1.36,3.069,,65.38,BBH,-1.50367,0.221079,0.00429626,0.905072 beta-lactamase_0_A230R,beta-lactamase_0_230,TEM-1,beta-lactamase_0,P62593,0.905092,NO,230,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.154,-3.858,2.704,,0.01,E,B,0.46,-1.17,2.179,,50,HHA,-1.079,0.0500837,0.00516841,0.905092 beta-lactamase_0_V157Y,beta-lactamase_0_157,TEM-1,beta-lactamase_0,P62593,0.905096,NO,157,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.751,-2.838,1.087,,0.308,S,a,0.44,-0.75,3.106,,69.58,BHP,-2.00767,0.0500837,0.00506849,0.905096 beta-lactamase_156_D83L,beta-lactamase_156_83,TEM-1,beta-lactamase_156,P62593,0.905124,NO,83,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.066,-3.79,2.724,,0.354,H,A,0.75,0.22,1.281,,48.95,HAH,-1.34733,0.111618,0.00205968,0.905124 kka2_1:4_L53C,kka2_1:4_53,Kka2,kka2_1:4,P00552,0.905138,NO,53,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-2.681,-5.19,2.509,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.168804,0.00671168,0.905138 beta-lactamase_0_R275C,beta-lactamase_0_275,TEM-1,beta-lactamase_0,P62593,0.905142,NO,275,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.0500837,0.0141984,0.905142 beta-lactamase_0_V260F,beta-lactamase_0_260,TEM-1,beta-lactamase_0,P62593,0.905197,NO,260,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.0500837,0.00471757,0.905197 kka2_1:8_D227F,kka2_1:8_227,Kka2,kka2_1:8,P00552,0.905203,NO,227,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.758,-4.199,2.441,,0.128,H,A,0.75,-0.63,0.281,,56.06,BAH,-1.43067,0.100394,0.00745029,0.905203 kka2_1:8_D227F,kka2_1:8_227,Kka2,kka2_1:8,P00552,0.905203,NO,227,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.758,-4.199,2.441,,0.128,H,A,0.75,-0.63,0.281,,56.06,BAH,-1.43067,0.100394,0.00745029,0.905203 kka2_1:2_L94R,kka2_1:2_94,Kka2,kka2_1:2,P00552,0.905204,NO,94,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.618,-3.994,2.376,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.295029,0.00520888,0.905204 PSD95pdz3_G333P,PSD95pdz3_333,PSD95pdz3,PSD95pdz3,P31016,0.905229,NO,333,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.008,-3.561,2.553,5.09445,,,,,48.755,,,,AOA,-1.22533,0.0758425,0.00092544,0.905229 beta-lactamase_0_G216V,beta-lactamase_0_216,TEM-1,beta-lactamase_0,P62593,0.905287,NO,216,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.477,-3.793,2.316,,0.437,I,A,0.29,-0.58,0.834,,74.48,HOO,-1.68067,0.0500837,0.00639568,0.905287 beta-lactamase_0_A278L,beta-lactamase_0_278,TEM-1,beta-lactamase_0,P62593,0.905297,NO,278,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.348,,,,0.015,H,A,0.48,-0.85,4.624,,63.29,HHA,-1.41833,0.0500837,0.0310297,0.905297 beta-lactamase_P253Q,beta-lactamase_253,TEM-1,beta-lactamase,P62593,0.905348,NO,253,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-2.253,-2.666,0.413,5.24842,0.308,,B,0.73,-0.46,2.293,,73.08,BOP,-2.10633,0.221079,0.00786358,0.905348 E1_Ubiquitin_L43A,E1_Ubiquitin_43,Uba1,E1_Ubiquitin,P0CG63,0.905393,NO,43,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.188,-2.888,1.7,,,E,B,,-1.17,,,,BHH,-1.30733,0.18783,0.00190185,0.905393 E1_Ubiquitin_T68L,E1_Ubiquitin_68,Uba1,E1_Ubiquitin,P0CG63,0.905393,NO,68,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,,,,,,,,,,,,,OPH,-1.039,0.18783,0.00314321,0.905393 kka2_1:4_T72N,kka2_1:4_72,Kka2,kka2_1:4,P00552,0.905393,NO,72,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.38,-3.767,1.387,,0.784,H,A,0.82,0.29,6.463,,65.53,HPP,-2.238,0.168804,0.00750756,0.905393 beta-lactamase_39_I258E,beta-lactamase_39_258,TEM-1,beta-lactamase_39,P62593,0.905473,NO,258,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.0495842,0.007931,0.905473 beta-lactamase_0_T263Q,beta-lactamase_0_263,TEM-1,beta-lactamase_0,P62593,0.905523,NO,263,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.0500837,0.0110582,0.905523 beta-lactamase_T187M,beta-lactamase_187,TEM-1,beta-lactamase,P62593,0.905528,NO,187,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.401,-4.516,3.115,5.11453,0.007,H,A,0.3,-1.19,1.751,,67.48,PPH,-1.69633,0.221079,0.00491782,0.905528 Pab1_G126N,Pab1_126,Pab1,Pab1,P04147,0.905543,NO,126,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.985,-3.411,2.426,,0.011,T,A,0.46,-0.07,2.349,,80.42,OOP,-1.032,0.175299,0.00109814,0.905543 Pab1_K156I,Pab1_156,Pab1,Pab1,P04147,0.905546,NO,156,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.083,-3.827,2.744,,0.406,E,B,1.82,-0.26,,,,PBH,-1.58167,0.175299,0.000316767,0.905546 gb1_T279L,gb1_279,gb1,gb1,P06654,0.905547,NO,279,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.32,-2.73,1.41,,,,,,,0.529,,35.71,HPH,-1.50067,0.177985,0.00421454,0.905547 beta-lactamase_0_A185H,beta-lactamase_0_185,TEM-1,beta-lactamase_0,P62593,0.905563,NO,185,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.406,-4.889,3.483,,,H,A,0.46,-1.02,1.203,,65.03,HHP,-1.84033,0.0500837,0.00467449,0.905563 kka2_1:2_A9N,kka2_1:2_9,Kka2,kka2_1:2,P00552,0.905572,NO,9,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.079,-2.623,0.544,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.295029,0.00273264,0.905572 beta-lactamase_0_T116K,beta-lactamase_0_116,TEM-1,beta-lactamase_0,P62593,0.905581,NO,116,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.28,-3.42,2.14,,0.115,E,B,0.22,-0.12,1.356,,67.48,HPH,-1.39967,0.0500837,0.00336175,0.905581 beta-lactamase_0_P172Y,beta-lactamase_0_172,TEM-1,beta-lactamase_0,P62593,0.905593,NO,172,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.998,-4.368,3.37,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.0500837,0.00312594,0.905593 beta-lactamase_L19R,beta-lactamase_19,TEM-1,beta-lactamase,P62593,0.905622,NO,19,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.682,-3.907,2.225,,,,,,,4.261,,93.01,OHO,-1.894,0.221079,0.00215974,0.905622 kka2_1:2_D157N,kka2_1:2_157,Kka2,kka2_1:2,P00552,0.905656,NO,157,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.993,-2.434,1.441,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.295029,0.0042313,0.905656 kka2_1:4_G151C,kka2_1:4_151,Kka2,kka2_1:4,P00552,0.905768,NO,151,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.873,-5.156,4.283,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.168804,0.00339918,0.905768 beta-lactamase_R81Y,beta-lactamase_81,TEM-1,beta-lactamase,P62593,0.90577,NO,81,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.466,-4.271,2.805,5.12166,0.218,H,A,0.68,1.66,1.236,,50,PBH,-1.60667,0.221079,0.00499763,0.90577 beta-lactamase_39_G216M,beta-lactamase_39_216,TEM-1,beta-lactamase_39,P62593,0.905775,NO,216,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.477,-4.925,3.448,,0.437,I,A,0.29,-0.58,0.834,,74.48,HOO,-1.68067,0.0495842,0.00639568,0.905775 PSD95pdz3_V328K,PSD95pdz3_328,PSD95pdz3,PSD95pdz3,P31016,0.90579,NO,328,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.465,-3.364,1.899,5.28275,,,,,16.8775,,,,HHO,-1.36767,0.0758425,0.000986706,0.90579 gb1_A249N,gb1_249,gb1,gb1,P06654,0.905836,NO,249,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.739,-3.708,1.969,,,,,,,0.252,,44.87,AHH,-1.67367,0.177985,0.00333585,0.905836 PSD95pdz3_G330P,PSD95pdz3_330,PSD95pdz3,PSD95pdz3,P31016,0.905858,NO,330,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.008,-3.561,2.553,4.68351,,,,,31.405,,,,OOA,-1.14,0.0758425,0.000962386,0.905858 beta-lactamase_2500_R162N,beta-lactamase_2500_162,TEM-1,beta-lactamase_2500,P62593,0.905861,NO,162,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.016,-3.588,2.572,,0.124,S,B,1.2,-0.37,6.199,,64.69,ABH,-1.25,0.361275,0.000561334,0.905861 kka2_1:8_R38V,kka2_1:8_38,Kka2,kka2_1:8,P00552,0.905904,NO,38,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.207,-2.691,1.484,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.100394,0.00372499,0.905904 kka2_1:8_R38V,kka2_1:8_38,Kka2,kka2_1:8,P00552,0.905904,NO,38,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.207,-2.691,1.484,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.100394,0.00372499,0.905904 WW_domain_K181M,WW_domain_181,Yap65,WW_domain,P46937,0.905906,NO,181,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.35,-4.25,2.9,5.0864,,,,,,0.176,,15.87,HBP,-1.247,0.153962,0.0033022,0.905906 kka2_1:4_Y244C,kka2_1:4_244,Kka2,kka2_1:4,P00552,0.905933,NO,244,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-0.775,-4.89,4.115,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.168804,0.00453187,0.905933 kka2_1:4_V84F,kka2_1:4_84,Kka2,kka2_1:4,P00552,0.905941,NO,84,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-2.279,-4.266,1.987,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.168804,0.00724019,0.905941 WW_domain_Q200M,WW_domain_200,Yap65,WW_domain,P46937,0.905991,NO,200,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-1.599,-4.237,2.638,5.37476,,,,,,1.9,,70.04,HPA,-1.484,0.153962,0.00300397,0.905991 beta-lactamase_P249A,beta-lactamase_249,TEM-1,beta-lactamase,P62593,0.905996,NO,249,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.312,-2.574,1.262,5.10655,0.256,S,B,0.99,0.04,0.479,,72.73,OOA,-1.81367,0.221079,0.00220169,0.905996 Pab1_K166Y,Pab1_166,Pab1,Pab1,P04147,0.906012,NO,166,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.262,-4.055,2.793,,0.299,,l,,0,,,,PBO,-1.21033,0.175299,0.0011038,0.906012 beta-lactamase_0_F70Q,beta-lactamase_0_70,TEM-1,beta-lactamase_0,P62593,0.906057,NO,70,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.169,-4.201,3.032,,,H,A,0.58,-1.34,2.153,,63.99,PHB,-0.980667,0.0500837,0.00193499,0.906057 beta-lactamase_625_G142H,beta-lactamase_625_142,TEM-1,beta-lactamase_625,P62593,0.906177,NO,142,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.707,-4.678,3.971,,0.034,,p,0.29,-0.64,1.35,,64.69,OOO,-0.834,0.213352,0.00060149,0.906177 beta-lactamase_0_L205T,beta-lactamase_0_205,TEM-1,beta-lactamase_0,P62593,0.906178,NO,205,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.922,-3.476,2.554,,,H,A,0.55,-0.46,1.065,,42.31,PHH,-1.57767,0.0500837,0.00255802,0.906178 beta-lactamase_0_Q204H,beta-lactamase_0_204,TEM-1,beta-lactamase_0,P62593,0.906193,NO,204,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-1.382,-3.09,1.708,,0.204,H,A,0.64,0.09,2.646,,66.08,PPH,-1.49067,0.0500837,0.00364106,0.906193 beta-lactamase_I244M,beta-lactamase_244,TEM-1,beta-lactamase,P62593,0.906193,NO,244,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.555,-4.138,2.583,5.35885,,E,B,0.01,-0.84,0.379,,77.62,HHH,-1.385,0.221079,0.00605379,0.906193 PSD95pdz3_S339Q,PSD95pdz3_339,PSD95pdz3,PSD95pdz3,P31016,0.90622,NO,339,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.519,-3.356,1.837,5.34493,,,,,12.2167,,,,HPH,-1.55767,0.0758425,0.00084982,0.90622 kka2_1:4_R202G,kka2_1:4_202,Kka2,kka2_1:4,P00552,0.906225,NO,202,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.761,-2.403,0.642,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.168804,0.00696498,0.906225 kka2_1:8_R140C,kka2_1:8_140,Kka2,kka2_1:8,P00552,0.906254,NO,140,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.351,-5.118,3.767,,0.12,H,A,0.16,0.2,2.874,,53.03,BBH,-1.885,0.100394,0.00430167,0.906254 kka2_1:8_R140C,kka2_1:8_140,Kka2,kka2_1:8,P00552,0.906254,NO,140,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.351,-5.118,3.767,,0.12,H,A,0.16,0.2,2.874,,53.03,BBH,-1.885,0.100394,0.00430167,0.906254 PSD95pdz3_N326Q,PSD95pdz3_326,PSD95pdz3,PSD95pdz3,P31016,0.906263,NO,326,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-1.41,-3.356,1.946,5.52537,,,,,19.0688,,,,HPH,-1.52133,0.0758425,0.00101078,0.906263 beta-lactamase_0_G226M,beta-lactamase_0_226,TEM-1,beta-lactamase_0,P62593,0.906265,NO,226,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.461,-4.924,3.463,,0.701,T,l,0.29,-0.25,23.034,23.034,74.48,HOH,-1.42933,0.0500837,0.00665294,0.906265 kka2_1:8_Q219S,kka2_1:8_219,Kka2,kka2_1:8,P00552,0.906275,NO,219,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-0.93,-3.233,2.303,,0.088,H,A,0.4,-0.85,0.897,,50,HPA,-1.05167,0.100394,0.00237913,0.906275 kka2_1:8_Q219S,kka2_1:8_219,Kka2,kka2_1:8,P00552,0.906275,NO,219,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-0.93,-3.233,2.303,,0.088,H,A,0.4,-0.85,0.897,,50,HPA,-1.05167,0.100394,0.00237913,0.906275 kka2_1:8_S105N,kka2_1:8_105,Kka2,kka2_1:8,P00552,0.906341,NO,105,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.945,-3.821,1.876,,0.056,S,B,0.27,-1.04,2.115,,65.53,PPB,-2.17033,0.100394,0.00847233,0.906341 kka2_1:8_S105N,kka2_1:8_105,Kka2,kka2_1:8,P00552,0.906341,NO,105,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.945,-3.821,1.876,,0.056,S,B,0.27,-1.04,2.115,,65.53,PPB,-2.17033,0.100394,0.00847233,0.906341 PSD95pdz3_S339R,PSD95pdz3_339,PSD95pdz3,PSD95pdz3,P31016,0.906363,NO,339,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.519,-3.39,1.871,5.34493,,,,,12.2167,,,,HPH,-1.55767,0.0758425,0.00084982,0.906363 beta-lactamase_0_D177Y,beta-lactamase_0_177,TEM-1,beta-lactamase_0,P62593,0.906367,NO,177,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.967,-4.413,3.446,,0.006,T,L,0.75,-1.02,3.536,,64.69,BAP,-0.873667,0.0500837,0.000864022,0.906367 beta-lactamase_2500_A211T,beta-lactamase_2500_211,TEM-1,beta-lactamase_2500,P62593,0.906385,NO,211,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.896,-2.901,1.005,,0.369,T,A,0.46,-0.69,2.061,,77.62,AHA,-1.94633,0.361275,0.00648183,0.906385 beta-lactamase_R7V,beta-lactamase_7,TEM-1,beta-lactamase,P62593,0.906388,NO,7,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.683,-3.362,1.679,,,,,,,2.44,,67.13,HBH,-1.96267,0.221079,0.00211375,0.906388 beta-lactamase_0_A200C,beta-lactamase_0_200,TEM-1,beta-lactamase_0,P62593,0.906414,NO,200,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.878,-5.005,3.127,,0.757,H,A,0.46,-0.19,16.368,16.368,77.62,HHP,-2.001,0.0500837,0.0060056,0.906414 beta-lactamase_0_R275P,beta-lactamase_0_275,TEM-1,beta-lactamase_0,P62593,0.906429,NO,275,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.0500837,0.0141984,0.906429 kka2_1:2_A172I,kka2_1:2_172,Kka2,kka2_1:2,P00552,0.906457,NO,172,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.757,-3.215,1.458,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.295029,0.0079265,0.906457 beta-lactamase_0_R242L,beta-lactamase_0_242,TEM-1,beta-lactamase_0,P62593,0.906467,NO,242,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.0500837,0.00452879,0.906467 beta-lactamase_E62H,beta-lactamase_62,TEM-1,beta-lactamase,P62593,0.906468,NO,62,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.193,-4.429,3.236,5.93066,0.342,S,B,1.52,-0.3,3.139,,73.08,AAB,-1.417,0.221079,0.00264802,0.906468 beta-lactamase_V101L,beta-lactamase_101,TEM-1,beta-lactamase,P62593,0.906468,NO,101,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.295,-2.095,0.8,5.49045,0.342,,B,0.96,0,1.675,,73.08,HHA,-1.54367,0.221079,0.00374492,0.906468 PSD95pdz3_A375C,PSD95pdz3_375,PSD95pdz3,PSD95pdz3,P31016,0.906475,NO,375,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.307,-4.094,2.787,5.05512,,,,,13.888,,,,PHH,-1.43767,0.0758425,0.000356809,0.906475 kka2_1:8_W15V,kka2_1:8_15,Kka2,kka2_1:8,P00552,0.906516,NO,15,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-1.392,-3.309,1.917,,0.01,G,A,1.51,0.15,0.827,,52.27,HHH,-2.10533,0.100394,0.00585505,0.906516 kka2_1:8_W15V,kka2_1:8_15,Kka2,kka2_1:8,P00552,0.906516,NO,15,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-1.392,-3.309,1.917,,0.01,G,A,1.51,0.15,0.827,,52.27,HHH,-2.10533,0.100394,0.00585505,0.906516 PSD95pdz3_I336L,PSD95pdz3_336,PSD95pdz3,PSD95pdz3,P31016,0.906538,NO,336,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.63,-2.14,0.51,5.11321,,,,,13.6363,,,,OHH,-1.38733,0.0758425,0.000887923,0.906538 beta-lactamase_2500_V72T,beta-lactamase_2500_72,TEM-1,beta-lactamase_2500,P62593,0.90657,NO,72,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.658,-2.757,1.099,,,H,A,0.44,-1.03,2.079,,65.73,BHH,-1.32167,0.361275,0.00501194,0.90657 kka2_1:8_L67Y,kka2_1:8_67,Kka2,kka2_1:8,P00552,0.906647,NO,67,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.741,-3.966,3.225,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.100394,0.00102787,0.906647 kka2_1:8_L67Y,kka2_1:8_67,Kka2,kka2_1:8,P00552,0.906647,NO,67,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.741,-3.966,3.225,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.100394,0.00102787,0.906647 beta-lactamase_2500_L120M,beta-lactamase_2500_120,TEM-1,beta-lactamase_2500,P62593,0.906674,NO,120,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.044,-4.046,3.002,,,H,A,0.55,-1.13,2.48,,64.69,AHO,-1.13633,0.361275,0.00143563,0.906674 beta-lactamase_0_L111A,beta-lactamase_0_111,TEM-1,beta-lactamase_0,P62593,0.906682,NO,111,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.76,-2.229,0.469,,0.328,T,A,0.55,0.93,1.966,,64.34,BHP,-1.884,0.0500837,0.00480671,0.906682 PSD95pdz3_A370D,PSD95pdz3_370,PSD95pdz3,PSD95pdz3,P31016,0.906687,NO,370,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.307,-3.375,2.068,5.22304,,,,,17.284,,,,PHP,-1.57967,0.0758425,0.000429106,0.906687 kka2_1:8_D134Y,kka2_1:8_134,Kka2,kka2_1:8,P00552,0.906712,NO,134,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.969,-4.401,3.432,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.100394,0.00270812,0.906712 kka2_1:8_D134Y,kka2_1:8_134,Kka2,kka2_1:8,P00552,0.906712,NO,134,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.969,-4.401,3.432,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.100394,0.00270812,0.906712 beta-lactamase_A23S,beta-lactamase_23,TEM-1,beta-lactamase,P62593,0.906747,NO,23,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.548,-2.111,0.563,,,,,,,0.801,,93.01,HHB,-2.235,0.221079,0.00245563,0.906747 beta-lactamase_G85Y,beta-lactamase_85,TEM-1,beta-lactamase,P62593,0.906747,NO,85,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.011,-4.409,3.398,5.58951,0.805,T,l,0.23,1.7,1.468,,63.64,HOP,-1.68733,0.221079,0.00252173,0.906747 beta-lactamase_0_L74R,beta-lactamase_0_74,TEM-1,beta-lactamase_0,P62593,0.906752,NO,74,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.296,-3.939,2.643,,,H,A,0.55,-0.91,1.46,,50,HHO,-1.34933,0.0500837,0.00493255,0.906752 kka2_1:8_D157E,kka2_1:8_157,Kka2,kka2_1:8,P00552,0.906756,NO,157,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.993,-2.48,1.487,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.100394,0.0042313,0.906756 kka2_1:8_D157E,kka2_1:8_157,Kka2,kka2_1:8,P00552,0.906756,NO,157,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.993,-2.48,1.487,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.100394,0.0042313,0.906756 kka2_1:8_D157T,kka2_1:8_157,Kka2,kka2_1:8,P00552,0.906778,NO,157,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.993,-3.488,2.495,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.100394,0.0042313,0.906778 kka2_1:8_D157T,kka2_1:8_157,Kka2,kka2_1:8,P00552,0.906778,NO,157,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.993,-3.488,2.495,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.100394,0.0042313,0.906778 Pab1_Y143I,Pab1_143,Pab1,Pab1,P04147,0.906813,NO,143,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-1.961,-3.661,1.7,,0.409,H,A,,0.3,,,,HHA,-1.39633,0.175299,0.00160364,0.906813 beta-lactamase_A170P,beta-lactamase_170,TEM-1,beta-lactamase,P62593,0.906828,NO,170,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.237,-3.899,2.662,5.19261,0.126,,L,2.34,-0.35,2.427,,64.69,AHH,-1.63267,0.221079,0.00431903,0.906828 kka2_1:1_Q26R,kka2_1:1_26,Kka2,kka2_1:1,P00552,0.906842,NO,26,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.18,-1.791,-0.389,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.520039,0.00708962,0.906842 kka2_1:2_R121L,kka2_1:2_121,Kka2,kka2_1:2,P00552,0.90686,NO,121,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.552,-2.477,0.925,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.295029,0.00523326,0.90686 beta-lactamase_2500_A222M,beta-lactamase_2500_222,TEM-1,beta-lactamase_2500,P62593,0.906896,NO,222,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.103,-4.656,2.553,,0.233,H,A,0.46,-0.25,0.379,,77.62,PHH,-1.63733,0.361275,0.00466094,0.906896 Pab1_K140L,Pab1_140,Pab1,Pab1,P04147,0.906909,NO,140,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.083,-3.175,2.092,,0.345,H,A,,-0.73,,,,PBH,-1.20767,0.175299,0.000337366,0.906909 beta-lactamase_2500_T147M,beta-lactamase_2500_147,TEM-1,beta-lactamase_2500,P62593,0.906924,NO,147,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.149,-4.573,3.424,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.361275,0.00226017,0.906924 beta-lactamase_0_V31W,beta-lactamase_0_31,TEM-1,beta-lactamase_0,P62593,0.906945,NO,31,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.822,-5.287,3.465,,,H,A,0.44,-0.46,4.126,,73.78,BHB,-2.03767,0.0500837,0.00478065,0.906945 kka2_1:2_W15L,kka2_1:2_15,Kka2,kka2_1:2,P00552,0.90695,NO,15,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-1.392,-1.643,0.251,,0.01,G,A,0.47,0.15,2.586,,52.27,HHH,-2.10533,0.295029,0.00585505,0.90695 beta-lactamase_39_S233N,beta-lactamase_39_233,TEM-1,beta-lactamase_39,P62593,0.906969,NO,233,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.886,-2.73,0.844,,0.016,E,B,0.27,-1.01,5.361,,77.62,BPO,-1.17267,0.0495842,0.00311415,0.906969 beta-lactamase_0_A247Q,beta-lactamase_0_247,TEM-1,beta-lactamase_0,P62593,0.906972,NO,247,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.0500837,0.00611275,0.906972 beta-lactamase_2500_A170N,beta-lactamase_2500_170,TEM-1,beta-lactamase_2500,P62593,0.906996,NO,170,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.237,-2.833,1.596,,0.126,,L,0.46,-0.35,2.427,,64.69,AHH,-1.63267,0.361275,0.00431903,0.906996 kka2_1:8_L241C,kka2_1:8_241,Kka2,kka2_1:8,P00552,0.906999,NO,241,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.158,-3.073,1.915,,0.08,H,A,1.59,-0.82,1.136,,63.26,HHH,-1.58533,0.100394,0.0117299,0.906999 kka2_1:8_L241C,kka2_1:8_241,Kka2,kka2_1:8,P00552,0.906999,NO,241,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.158,-3.073,1.915,,0.08,H,A,1.59,-0.82,1.136,,63.26,HHH,-1.58533,0.100394,0.0117299,0.906999 kka2_1:2_T187S,kka2_1:2_187,Kka2,kka2_1:2,P00552,0.907008,NO,187,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.273,-2.293,1.02,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.295029,0.00693073,0.907008 beta-lactamase_39_Q203Y,beta-lactamase_39_203,TEM-1,beta-lactamase_39,P62593,0.907018,NO,203,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.168,-4.35,2.182,,0.47,H,A,0.64,-0.38,1.453,,65.38,BPP,-1.614,0.0495842,0.00631514,0.907018 WW_domain_I193V,WW_domain_193,Yap65,WW_domain,P46937,0.907025,NO,193,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.993,-2.386,0.393,6.15906,,,,,,1.833,,83.33,BHA,-1.756,0.153962,0.00587613,0.907025 beta-lactamase_2500_N173I,beta-lactamase_2500_173,TEM-1,beta-lactamase_2500,P62593,0.907035,NO,173,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-2.663,-4.172,1.509,,1.044,T,l,0.61,1.25,1.88,,77.62,OPA,-1.46633,0.361275,0.0033769,0.907035 kka2_1:8_L94A,kka2_1:8_94,Kka2,kka2_1:8,P00552,0.907039,NO,94,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.618,-3.195,1.577,,0.058,E,B,1.59,-0.52,2.197,,56.06,HHO,-1.612,0.100394,0.00520888,0.907039 kka2_1:8_L94A,kka2_1:8_94,Kka2,kka2_1:8,P00552,0.907039,NO,94,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.618,-3.195,1.577,,0.058,E,B,1.59,-0.52,2.197,,56.06,HHO,-1.612,0.100394,0.00520888,0.907039 beta-lactamase_2500_S283D,beta-lactamase_2500_283,TEM-1,beta-lactamase_2500,P62593,0.907079,NO,283,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.361275,0.0429138,0.907079 beta-lactamase_F58T,beta-lactamase_58,TEM-1,beta-lactamase,P62593,0.907103,NO,58,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-2.914,-2.91,-0.004,5.55634,0.266,E,B,1.33,-0.07,2.467,,77.62,PHB,-2.059,0.221079,0.00523369,0.907103 beta-lactamase_R41F,beta-lactamase_41,TEM-1,beta-lactamase,P62593,0.907103,NO,41,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-0.942,-4.29,3.348,5.69185,0.321,E,B,0.91,-0.07,4.357,,65.03,HBH,-1.30267,0.221079,0.00123327,0.907103 beta-lactamase_0_D252W,beta-lactamase_0_252,TEM-1,beta-lactamase_0,P62593,0.907155,NO,252,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.0500837,0.00575769,0.907155 E1_Ubiquitin_L71C,E1_Ubiquitin_71,Uba1,E1_Ubiquitin,P0CG63,0.907162,NO,71,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.039,-4.454,3.415,,0.591,E,B,,-0.69,,,,BHB,-1.19433,0.18783,0.00148349,0.907162 beta-lactamase_2500_L28T,beta-lactamase_2500_28,TEM-1,beta-lactamase_2500,P62593,0.907172,NO,28,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.579,-3.444,1.865,,0.277,H,A,0.55,-0.16,2.716,,93.01,PHH,-2.11333,0.361275,0.00359321,0.907172 PSD95pdz3_R318C,PSD95pdz3_318,PSD95pdz3,PSD95pdz3,P31016,0.907285,NO,318,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.582,-4.769,3.187,4.94876,,,,,17.5609,,,,BBO,-1.40567,0.0758425,0.00110471,0.907285 beta-lactamase_0_K71T,beta-lactamase_0_71,TEM-1,beta-lactamase_0,P62593,0.90731,NO,71,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-0.8,-3.421,2.621,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.0500837,0.00103192,0.90731 beta-lactamase_0_M184R,beta-lactamase_0_184,TEM-1,beta-lactamase_0,P62593,0.907325,NO,184,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.593,-3.928,2.335,,,H,A,0.55,-0.87,13.292,13.292,62.94,HHH,-1.41,0.0500837,0.00356019,0.907325 PSD95pdz3_E352I,PSD95pdz3_352,PSD95pdz3,PSD95pdz3,P31016,0.907342,NO,352,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.587,-3.582,1.995,5.49659,,,,,24.2,2.525,,86.88,OAH,-1.314,0.0758425,0.000892231,0.907342 beta-lactamase_D231D,beta-lactamase_231,TEM-1,beta-lactamase,P62593,0.907353,NO,231,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.816,-0.816,,5.06651,,E,B,1.22,-1.06,0.319,,65.38,HAB,-0.994,0.221079,0.00107395,0.907353 beta-lactamase_2500_L191V,beta-lactamase_2500_191,TEM-1,beta-lactamase_2500,P62593,0.907363,NO,191,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.087,-2.22,1.133,,,H,A,0.55,0.09,1.703,,63.29,BHH,-1.445,0.361275,0.00263549,0.907363 beta-lactamase_0_A247D,beta-lactamase_0_247,TEM-1,beta-lactamase_0,P62593,0.907375,NO,247,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.0500837,0.00611275,0.907375 beta-lactamase_0_A34W,beta-lactamase_0_34,TEM-1,beta-lactamase_0,P62593,0.907388,NO,34,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.059,-2.89,0.831,,,H,A,0.46,-0.54,3.998,,73.78,AHA,-1.74967,0.0500837,0.00407913,0.907388 beta-lactamase_F58V,beta-lactamase_58,TEM-1,beta-lactamase,P62593,0.907399,NO,58,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-2.914,-3.697,0.783,5.55634,0.266,E,B,1.33,-0.07,2.467,,77.62,PHB,-2.059,0.221079,0.00523369,0.907399 Pab1_F146S,Pab1_146,Pab1,Pab1,P04147,0.907422,NO,146,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.149,-3.428,2.279,,0.006,H,A,,0.75,,,,PHP,-1.161,0.175299,0.000329265,0.907422 beta-lactamase_625_A247W,beta-lactamase_625_247,TEM-1,beta-lactamase_625,P62593,0.90745,NO,247,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.213352,0.00611275,0.90745 beta-lactamase_0_L199Y,beta-lactamase_0_199,TEM-1,beta-lactamase_0,P62593,0.907548,NO,199,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-2.942,-4.431,1.489,,0.832,H,A,0.55,0.42,10.85,10.85,77.62,PHH,-2.32933,0.0500837,0.0048649,0.907548 kka2_1:2_L123I,kka2_1:2_123,Kka2,kka2_1:2,P00552,0.907557,NO,123,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.888,-2.453,1.565,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.295029,0.00325188,0.907557 beta-lactamase_39_L146E,beta-lactamase_39_146,TEM-1,beta-lactamase_39,P62593,0.907602,NO,146,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.462,-3.93,2.468,,0.007,H,A,0.55,-0.56,1.953,,64.69,AHP,-1.656,0.0495842,0.00474542,0.907602 kka2_1:2_E142C,kka2_1:2_142,Kka2,kka2_1:2,P00552,0.907603,NO,142,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.221,-5.114,2.893,,0.471,H,A,1.52,0.85,3.693,,65.53,HAB,-2.08033,0.295029,0.00748883,0.907603 kka2_1:2_R122H,kka2_1:2_122,Kka2,kka2_1:2,P00552,0.907604,NO,122,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.175,-3.287,1.112,,0.487,H,A,1.2,0.26,16.436,16.436,71.59,BBH,-1.53833,0.295029,0.00736512,0.907604 beta-lactamase_625_N134D,beta-lactamase_625_134,TEM-1,beta-lactamase_625,P62593,0.907615,NO,134,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-0.879,-3.087,2.208,,0.138,H,A,0.61,-0.6,3.776,,53.15,HPH,-1.02233,0.213352,0.000644786,0.907615 beta-lactamase_M127A,beta-lactamase_127,TEM-1,beta-lactamase,P62593,0.90762,NO,127,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-2.251,-3.303,1.052,5.40552,0.312,S,A,1.07,0.32,1.671,,72.73,PHP,-1.40433,0.221079,0.00437927,0.90762 kka2_1:8_L102M,kka2_1:8_102,Kka2,kka2_1:8,P00552,0.907671,NO,102,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.804,-2.818,2.014,,,T,A,1.59,-1.17,0.97,,42.42,AHH,-1.398,0.100394,0.00201332,0.907671 kka2_1:8_L102M,kka2_1:8_102,Kka2,kka2_1:8,P00552,0.907671,NO,102,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.804,-2.818,2.014,,,T,A,1.59,-1.17,0.97,,42.42,AHH,-1.398,0.100394,0.00201332,0.907671 beta-lactamase_0_I280T,beta-lactamase_0_280,TEM-1,beta-lactamase_0,P62593,0.907701,NO,280,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.0500837,0.0530888,0.907701 kka2_1:2_A255D,kka2_1:2_255,Kka2,kka2_1:2,P00552,0.907734,NO,255,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.715,-2.352,0.637,,0.466,H,A,0.46,-0.52,5.144,,65.53,HHH,-1.71267,0.295029,0.0126809,0.907734 beta-lactamase_L73F,beta-lactamase_73,TEM-1,beta-lactamase,P62593,0.907761,NO,73,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.507,-2.19,0.683,5.84139,,H,A,1.75,-0.64,2.09,,67.83,HHH,-1.487,0.221079,0.00488983,0.907761 beta-lactamase_R91T,beta-lactamase_91,TEM-1,beta-lactamase,P62593,0.907761,NO,91,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.392,-2.721,1.329,5.92536,0.444,,B,0.68,0.96,1.318,,50.35,OBB,-1.73367,0.221079,0.00380226,0.907761 kka2_1:2_R202S,kka2_1:2_202,Kka2,kka2_1:2,P00552,0.907812,NO,202,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.761,-2.977,1.216,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.295029,0.00696498,0.907812 PSD95pdz3_G322Y,PSD95pdz3_322,PSD95pdz3,PSD95pdz3,P31016,0.90784,NO,322,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.008,-4.069,3.061,5.24791,,,,,16.3275,,,,POH,-1.24867,0.0758425,0.00105821,0.90784 gb1_G264D,gb1_264,gb1,gb1,P06654,0.907846,NO,264,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.833,-3.449,1.616,,,,,,,0.864,,44.87,POH,-1.61267,0.177985,0.0049716,0.907846 gb1_T242S,gb1_242,gb1,gb1,P06654,0.907846,NO,242,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.245,-2.671,1.426,,,,,,,,,,APP,-1.444,0.177985,0.00243886,0.907846 beta-lactamase_P25R,beta-lactamase_25,TEM-1,beta-lactamase,P62593,0.907864,NO,25,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.526,-3.8,2.274,5.6134,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.221079,0.00347571,0.907864 beta-lactamase_625_A215N,beta-lactamase_625_215,TEM-1,beta-lactamase_625,P62593,0.907894,NO,215,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.503,-3.679,2.176,,,,a,0.46,-0.93,3.583,,74.48,HHO,-1.42633,0.213352,0.00544007,0.907894 hsp90_N588W,hsp90_588,hsp90,hsp90,P02829,0.907903,NO,588,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-3.051,-4.251,0,4.61142,0.019,H,A,0.14,0.39,,,,HPH,-3.12167,0.368192,0.000222939,0.907903 beta-lactamase_0_G265Q,beta-lactamase_0_265,TEM-1,beta-lactamase_0,P62593,0.907926,NO,265,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-2.58,-2.659,0.079,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.0500837,0.00811926,0.907926 beta-lactamase_0_A182S,beta-lactamase_0_182,TEM-1,beta-lactamase_0,P62593,0.907942,NO,182,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.777,-2.825,1.048,,0.136,H,A,0.46,-0.66,10.765,10.765,93.01,OHH,-1.27367,0.0500837,0.00559099,0.907942 beta-lactamase_2500_G216A,beta-lactamase_2500_216,TEM-1,beta-lactamase_2500,P62593,0.907962,NO,216,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.477,-2.596,1.119,,0.437,I,A,0.29,-0.58,1.983,,74.48,HOO,-1.68067,0.361275,0.00639568,0.907962 kka2_1:2_G10C,kka2_1:2_10,Kka2,kka2_1:2,P00552,0.907966,NO,10,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.921,-5.151,3.23,,,,,,,2.192,,71.59,HOP,-2.10733,0.295029,0.00289233,0.907966 kka2_1:8_P12T,kka2_1:8_12,Kka2,kka2_1:8,P00552,0.907976,NO,12,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.853,-3.419,2.566,,,.,B,0.52,1.25,2.41,,48.11,POH,-1.80767,0.100394,0.00500011,0.907976 kka2_1:8_P12T,kka2_1:8_12,Kka2,kka2_1:8,P00552,0.907976,NO,12,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.853,-3.419,2.566,,,.,B,0.52,1.25,2.41,,48.11,POH,-1.80767,0.100394,0.00500011,0.907976 beta-lactamase_2500_E62Q,beta-lactamase_2500_62,TEM-1,beta-lactamase_2500,P62593,0.908008,NO,62,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.193,-2.5,1.307,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.361275,0.00264802,0.908008 beta-lactamase_0_R162E,beta-lactamase_0_162,TEM-1,beta-lactamase_0,P62593,0.90802,NO,162,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.016,-3.337,2.321,,0.124,S,B,1.2,-0.37,1.026,,64.69,ABH,-1.25,0.0500837,0.000561334,0.90802 beta-lactamase_2500_S283F,beta-lactamase_2500_283,TEM-1,beta-lactamase_2500,P62593,0.908026,NO,283,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.361275,0.0429138,0.908026 beta-lactamase_0_A185S,beta-lactamase_0_185,TEM-1,beta-lactamase_0,P62593,0.908035,NO,185,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.406,-3.291,1.885,,,H,A,0.46,-1.02,1.203,,65.03,HHP,-1.84033,0.0500837,0.00467449,0.908035 kka2_1:4_L184K,kka2_1:4_184,Kka2,kka2_1:4,P00552,0.908036,NO,184,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.496,-2.828,1.332,,0.489,E,B,1.59,-0.06,4.495,,63.26,AHH,-1.24833,0.168804,0.00518742,0.908036 beta-lactamase_0_E46V,beta-lactamase_0_46,TEM-1,beta-lactamase_0,P62593,0.908079,NO,46,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.94,-1.834,-0.106,,0.021,E,B,1.04,0.14,30.306,30.306,59.44,HAH,-2.079,0.0500837,0.00427568,0.908079 beta-lactamase_39_D36Q,beta-lactamase_39_36,TEM-1,beta-lactamase_39,P62593,0.908091,NO,36,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.732,-2.234,-0.498,,0.555,H,A,0.75,1.17,13.689,13.689,77.62,AAP,-1.91167,0.0495842,0.00476483,0.908091 beta-lactamase_156_T263R,beta-lactamase_156_263,TEM-1,beta-lactamase_156,P62593,0.908107,NO,263,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.111618,0.0110582,0.908107 beta-lactamase_0_A200M,beta-lactamase_0_200,TEM-1,beta-lactamase_0,P62593,0.908131,NO,200,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.878,-4.732,2.854,,0.757,H,A,0.46,-0.19,16.368,16.368,77.62,HHP,-2.001,0.0500837,0.0060056,0.908131 gb1_L231A,gb1_231,gb1,gb1,P06654,0.908131,NO,231,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.603,-2.995,1.392,,,,,,,0.219,,11.83,BHH,-1.82633,0.177985,0.00322797,0.908131 kka2_1:8_M116I,kka2_1:8_116,Kka2,kka2_1:8,P00552,0.90815,NO,116,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-2.482,-2.646,0.164,,,H,A,1.59,-0.88,4.659,,71.59,HHH,-1.63867,0.100394,0.00745147,0.90815 kka2_1:8_M116I,kka2_1:8_116,Kka2,kka2_1:8,P00552,0.90815,NO,116,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-2.482,-2.646,0.164,,,H,A,1.59,-0.88,4.659,,71.59,HHH,-1.63867,0.100394,0.00745147,0.90815 beta-lactamase_2500_Q204Y,beta-lactamase_2500_204,TEM-1,beta-lactamase_2500,P62593,0.908163,NO,204,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-1.382,-4.071,2.689,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.361275,0.00364106,0.908163 beta-lactamase_2500_E272M,beta-lactamase_2500_272,TEM-1,beta-lactamase_2500,P62593,0.908195,NO,272,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.361275,0.00545371,0.908195 beta-lactamase_E108F,beta-lactamase_108,TEM-1,beta-lactamase,P62593,0.908213,NO,108,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.46,-4.416,2.956,5.52079,0.572,G,A,0.52,1.87,1.973,,72.73,PAB,-1.437,0.221079,0.00413372,0.908213 beta-lactamase_F6H,beta-lactamase_6,TEM-1,beta-lactamase,P62593,0.908213,NO,6,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.847,-4.695,2.848,,,,,,,1.276,,67.83,BHB,-2.076,0.221079,0.00261627,0.908213 beta-lactamase_I206H,beta-lactamase_206,TEM-1,beta-lactamase,P62593,0.908213,NO,206,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-2.429,-4.842,2.413,5.3727,0.173,H,A,1,-0.34,2.061,,77.62,HHA,-1.805,0.221079,0.00528934,0.908213 beta-lactamase_P253N,beta-lactamase_253,TEM-1,beta-lactamase,P62593,0.908213,NO,253,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-2.253,-3.763,1.51,5.24842,0.308,,B,0.73,-0.46,2.293,,73.08,BOP,-2.10633,0.221079,0.00786358,0.908213 beta-lactamase_P25F,beta-lactamase_25,TEM-1,beta-lactamase,P62593,0.908213,NO,25,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.526,-4.406,2.88,5.6134,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.221079,0.00347571,0.908213 beta-lactamase_R176N,beta-lactamase_176,TEM-1,beta-lactamase,P62593,0.908213,NO,176,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-0.863,-3.448,2.585,5.61264,0.385,T,B,0.68,-0.63,,,,ABA,-1.38867,0.221079,0.00105554,0.908213 beta-lactamase_R92P,beta-lactamase_92,TEM-1,beta-lactamase,P62593,0.908213,NO,92,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.718,-3.033,1.315,5.65832,0.479,E,B,0.91,1.36,3.069,,65.38,BBH,-1.50367,0.221079,0.00429626,0.908213 beta-lactamase_X287D,beta-lactamase_287,TEM-1,beta-lactamase,P62593,0.908213,NO,287,X,D,XD,Stop,negativeCharge,5.71,5.0516,-0.6584,,132.5,133,0,141.9,111.1,-30.8,,,,,,,,,,,,,HXO,-1.111,0.221079,,0.908213 beta-lactamase_0_W163F,beta-lactamase_0_163,TEM-1,beta-lactamase_0,P62593,0.908217,NO,163,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-1.843,-3.138,1.295,,0.467,,B,0.47,-0.5,13.843,13.843,63.99,BHA,-1.269,0.0500837,0.00418955,0.908217 kka2_1:1_Q136R,kka2_1:1_136,Kka2,kka2_1:1,P00552,0.908224,NO,136,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-3.021,-1.428,-1.593,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.520039,0.00624149,0.908224 beta-lactamase_0_L219N,beta-lactamase_0_219,TEM-1,beta-lactamase_0,P62593,0.908235,NO,219,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.313,-4.217,2.904,,,I,A,0.55,-0.51,6.513,6.513,74.48,HHB,-1.21533,0.0500837,0.00664345,0.908235 beta-lactamase_0_L74A,beta-lactamase_0_74,TEM-1,beta-lactamase_0,P62593,0.908272,NO,74,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.296,-1.569,0.273,,,H,A,0.55,-0.91,1.46,,50,HHO,-1.34933,0.0500837,0.00493255,0.908272 beta-lactamase_156_L219Y,beta-lactamase_156_219,TEM-1,beta-lactamase_156,P62593,0.908284,NO,219,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.313,-3.958,2.645,,,I,A,0.55,-0.51,2.321,,74.48,HHB,-1.21533,0.111618,0.00664345,0.908284 beta-lactamase_0_M66R,beta-lactamase_0_66,TEM-1,beta-lactamase_0,P62593,0.908318,NO,66,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.362,-3.923,2.561,,0.013,,A,0.55,-0.7,1.204,,73.08,OHH,-1.49567,0.0500837,0.00412876,0.908318 beta-lactamase_625_D231S,beta-lactamase_625_231,TEM-1,beta-lactamase_625,P62593,0.90832,NO,231,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.816,-3.186,2.37,,,E,B,0.75,-1.06,1.025,,65.38,HAB,-0.994,0.213352,0.00107395,0.90832 beta-lactamase_0_T193W,beta-lactamase_0_193,TEM-1,beta-lactamase_0,P62593,0.90837,NO,193,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.914,-5.211,3.297,,0.439,H,a,0.22,0.33,11.546,11.546,63.99,HPO,-1.52133,0.0500837,0.00482669,0.90837 gb1_G264F,gb1_264,gb1,gb1,P06654,0.908416,NO,264,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.833,-3.928,2.095,,,,,,,0.864,,44.87,POH,-1.61267,0.177985,0.0049716,0.908416 gb1_K230G,gb1_230,gb1,gb1,P06654,0.908416,NO,230,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.701,-3.275,1.574,,,,,,,0.166,,11.83,HBH,-1.52867,0.177985,0.00331703,0.908416 kka2_1:8_L193C,kka2_1:8_193,Kka2,kka2_1:8,P00552,0.908417,NO,193,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.983,-4.807,3.824,,,G,A,1.59,-1.03,2.234,,65.53,OHO,-0.965333,0.100394,0.00480179,0.908417 kka2_1:8_L193C,kka2_1:8_193,Kka2,kka2_1:8,P00552,0.908417,NO,193,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.983,-4.807,3.824,,,G,A,1.59,-1.03,2.234,,65.53,OHO,-0.965333,0.100394,0.00480179,0.908417 beta-lactamase_2500_M127F,beta-lactamase_2500_127,TEM-1,beta-lactamase_2500,P62593,0.908425,NO,127,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-2.251,-3.969,1.718,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.361275,0.00437927,0.908425 kka2_1:1_V80R,kka2_1:1_80,Kka2,kka2_1:1,P00552,0.908514,NO,80,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.144,-4.199,3.055,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.520039,0.00488211,0.908514 beta-lactamase_0_W227M,beta-lactamase_0_227,TEM-1,beta-lactamase_0,P62593,0.908523,NO,227,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-0.982,-4.54,3.558,,0.272,,B,0.47,-0.29,3.782,,74.48,OHH,-1.595,0.0500837,0.00226019,0.908523 beta-lactamase_2500_R41S,beta-lactamase_2500_41,TEM-1,beta-lactamase_2500,P62593,0.908523,NO,41,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-0.942,-2.526,1.584,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.361275,0.00123327,0.908523 beta-lactamase_0_E279W,beta-lactamase_0_279,TEM-1,beta-lactamase_0,P62593,0.908562,NO,279,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.0500837,0.0192826,0.908562 beta-lactamase_2500_T147C,beta-lactamase_2500_147,TEM-1,beta-lactamase_2500,P62593,0.90857,NO,147,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.149,-4.804,3.655,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.361275,0.00226017,0.90857 kka2_1:8_R121D,kka2_1:8_121,Kka2,kka2_1:8,P00552,0.908584,NO,121,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.552,-3.714,2.162,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.100394,0.00523326,0.908584 kka2_1:8_R121D,kka2_1:8_121,Kka2,kka2_1:8,P00552,0.908584,NO,121,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.552,-3.714,2.162,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.100394,0.00523326,0.908584 beta-lactamase_E270G,beta-lactamase_270,TEM-1,beta-lactamase,P62593,0.908635,NO,270,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.723,-3.458,1.735,5.33196,0.422,H,A,0.52,1.15,1.745,,64.34,AAB,-1.70933,0.221079,0.00767762,0.908635 hsp90_M589Y,hsp90_589,hsp90,hsp90,P02829,0.908639,NO,589,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-3.858,-3.316,0,4.72723,0.032,H,A,0.84,0.31,,,,PHA,-3.24233,0.368192,0.000222939,0.908639 kka2_1:8_D183C,kka2_1:8_183,Kka2,kka2_1:8,P00552,0.908649,NO,183,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.204,-5.235,4.031,,0.518,.,b,0.75,0.25,0.347,,52.27,AAH,-1.40533,0.100394,0.00426304,0.908649 kka2_1:8_D183C,kka2_1:8_183,Kka2,kka2_1:8,P00552,0.908649,NO,183,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.204,-5.235,4.031,,0.518,.,b,0.75,0.25,0.347,,52.27,AAH,-1.40533,0.100394,0.00426304,0.908649 kka2_1:2_G95D,kka2_1:2_95,Kka2,kka2_1:2,P00552,0.908664,NO,95,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-2.403,-2.891,0.488,,0.126,E,B,0.29,-0.74,0.359,,71.59,HOA,-2.198,0.295029,0.00743616,0.908664 Pab1_K140Q,Pab1_140,Pab1,Pab1,P04147,0.90869,NO,140,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.083,-3.266,2.183,,0.345,H,A,,-0.73,,,,PBH,-1.20767,0.175299,0.000337366,0.90869 beta-lactamase_0_T178R,beta-lactamase_0_178,TEM-1,beta-lactamase_0,P62593,0.908712,NO,178,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-0.791,-3.708,2.917,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.0500837,0.000684366,0.908712 beta-lactamase_I171P,beta-lactamase_171,TEM-1,beta-lactamase,P62593,0.908795,NO,171,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-2.431,-4.052,1.621,5.22771,0.361,,B,1,0.53,1.66,,77.62,HHO,-1.55533,0.221079,0.00623355,0.908795 beta-lactamase_T27L,beta-lactamase_27,TEM-1,beta-lactamase,P62593,0.908795,NO,27,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.905,-2.65,0.745,5.39752,0.007,H,A,0.69,-0.37,0.745,,93.01,APH,-1.97933,0.221079,0.00306559,0.908795 beta-lactamase_0_P181K,beta-lactamase_0_181,TEM-1,beta-lactamase_0,P62593,0.908817,NO,181,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.813,-3.483,2.67,,,H,A,0.52,-1.14,1.357,,61.54,HOH,-1.795,0.0500837,0.000703122,0.908817 Pab1_I130T,Pab1_130,Pab1,Pab1,P04147,0.908858,NO,130,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.212,-3.239,2.027,,,E,B,1.23,0.01,,,,HHB,-1.188,0.175299,0.000351112,0.908858 beta-lactamase_625_Q86P,beta-lactamase_625_86,TEM-1,beta-lactamase_625,P62593,0.908904,NO,86,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.4,-3.985,1.585,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.213352,0.00450027,0.908904 beta-lactamase_0_L137H,beta-lactamase_0_137,TEM-1,beta-lactamase_0,P62593,0.908918,NO,137,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.03,-4.934,3.904,,,H,A,0.55,-0.38,0.328,,42.31,HHP,-1.58933,0.0500837,0.00278599,0.908918 beta-lactamase_39_L160K,beta-lactamase_39_160,TEM-1,beta-lactamase_39,P62593,0.908929,NO,160,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.977,-3.757,2.78,,0.022,,B,0.55,-0.6,0.895,,44.41,BHA,-0.936,0.0495842,0.00193775,0.908929 beta-lactamase_2500_D83Q,beta-lactamase_2500_83,TEM-1,beta-lactamase_2500,P62593,0.90894,NO,83,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.066,-3.681,2.615,,0.354,H,A,0.75,0.22,0.239,,48.95,HAH,-1.34733,0.361275,0.00205968,0.90894 beta-lactamase_0_N274G,beta-lactamase_0_274,TEM-1,beta-lactamase_0,P62593,0.908961,NO,274,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.0500837,0.0110418,0.908961 beta-lactamase_R159S,beta-lactamase_159,TEM-1,beta-lactamase,P62593,0.908993,NO,159,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-0.94,-3.411,2.471,5.64971,0.316,,B,0.68,-0.55,1.172,,64.34,PBH,-1.011,0.221079,0.00108472,0.908993 beta-lactamase_0_W288R,beta-lactamase_0_288,TEM-1,beta-lactamase_0,P62593,0.908999,NO,288,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,,,,,,,,,,,,,BHO,,0.0500837,,0.908999 Pab1_E176Y,Pab1_176,Pab1,Pab1,P04147,0.909001,NO,176,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.003,-4.287,2.284,,,,,,,,,,AAO,-2.09933,0.175299,0.00264426,0.909001 kka2_1:2_R18G,kka2_1:2_18,Kka2,kka2_1:2,P00552,0.909008,NO,18,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.055,-3.057,1.002,,0.474,T,A,1.2,0.54,8.405,8.405,71.59,ABH,-1.821,0.295029,0.00724065,0.909008 beta-lactamase_0_G52V,beta-lactamase_0_52,TEM-1,beta-lactamase_0,P62593,0.909024,NO,52,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.149,-3.738,2.589,,0.299,,l,0.29,-0.04,1.164,,64.69,POB,-1.66267,0.0500837,0.00340138,0.909024 Pab1_K156L,Pab1_156,Pab1,Pab1,P04147,0.909049,NO,156,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.083,-3.175,2.092,,0.406,E,B,1.82,-0.26,,,,PBH,-1.58167,0.175299,0.000316767,0.909049 PSD95pdz3_N326H,PSD95pdz3_326,PSD95pdz3,PSD95pdz3,P31016,0.90908,NO,326,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-1.41,-3.687,2.277,5.52537,,,,,19.0688,,,,HPH,-1.52133,0.0758425,0.00101078,0.90908 beta-lactamase_I11L,beta-lactamase_11,TEM-1,beta-lactamase,P62593,0.909107,NO,11,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.745,-2.797,1.052,,,,,,,3.135,,66.08,HHO,-1.79467,0.221079,0.00261325,0.909107 beta-lactamase_0_I171W,beta-lactamase_0_171,TEM-1,beta-lactamase_0,P62593,0.909113,NO,171,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-2.431,-5.376,2.945,,0.361,,B,0.48,0.53,16.954,16.954,77.62,HHO,-1.55533,0.0500837,0.00623355,0.909113 Pab1_F146Y,Pab1_146,Pab1,Pab1,P04147,0.909134,NO,146,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.149,-2.855,1.706,,0.006,H,A,,0.75,,,,PHP,-1.161,0.175299,0.000329265,0.909134 WW_domain_L190M,WW_domain_190,Yap65,WW_domain,P46937,0.909137,NO,190,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.404,-3.903,2.499,5.53598,,,,,,0.645,,56.55,HHP,-1.51833,0.153962,0.00249186,0.909137 beta-lactamase_625_D48M,beta-lactamase_625_48,TEM-1,beta-lactamase_625,P62593,0.909138,NO,48,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.101,-4.896,3.795,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.213352,0.0027273,0.909138 Pab1_K140A,Pab1_140,Pab1,Pab1,P04147,0.909146,NO,140,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.083,-2.895,1.812,,0.345,H,A,,-0.73,,,,PBH,-1.20767,0.175299,0.000337366,0.909146 beta-lactamase_L49T,beta-lactamase_49,TEM-1,beta-lactamase,P62593,0.909153,NO,49,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.897,-1.853,-0.044,5.86005,0.131,T,A,1.3,0.04,3.112,,64.69,AHP,-1.99233,0.221079,0.00401477,0.909153 kka2_1:8_D82R,kka2_1:8_82,Kka2,kka2_1:8,P00552,0.909166,NO,82,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.946,-2.957,1.011,,0.341,E,b,0.29,0.52,7.463,,63.64,HAH,-1.98,0.100394,0.00637516,0.909166 kka2_1:8_D82R,kka2_1:8_82,Kka2,kka2_1:8,P00552,0.909166,NO,82,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.946,-2.957,1.011,,0.341,E,b,0.29,0.52,7.463,,63.64,HAH,-1.98,0.100394,0.00637516,0.909166 kka2_1:8_G151R,kka2_1:8_151,Kka2,kka2_1:8,P00552,0.909169,NO,151,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.873,-2.905,2.032,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.100394,0.00339918,0.909169 kka2_1:8_G151R,kka2_1:8_151,Kka2,kka2_1:8,P00552,0.909169,NO,151,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.873,-2.905,2.032,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.100394,0.00339918,0.909169 beta-lactamase_0_Q203N,beta-lactamase_0_203,TEM-1,beta-lactamase_0,P62593,0.90918,NO,203,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.168,-3.727,1.559,,0.47,H,A,0.64,-0.38,14.541,14.541,65.38,BPP,-1.614,0.0500837,0.00631514,0.90918 beta-lactamase_L137V,beta-lactamase_137,TEM-1,beta-lactamase,P62593,0.9092,NO,137,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.03,-2.816,1.786,5.20117,,H,A,1.07,-0.38,0.674,,42.31,HHP,-1.58933,0.221079,0.00278599,0.9092 beta-lactamase_0_L191P,beta-lactamase_0_191,TEM-1,beta-lactamase_0,P62593,0.909225,NO,191,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.087,-4.09,3.003,,,H,A,0.55,0.09,12.255,12.255,63.29,BHH,-1.445,0.0500837,0.00263549,0.909225 Pab1_I183G,Pab1_183,Pab1,Pab1,P04147,0.909334,NO,183,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.302,-3.619,2.317,,0.308,T,B,1,1.08,1.29,,75.56,HHA,-1.27167,0.175299,0.000574345,0.909334 beta-lactamase_156_D161L,beta-lactamase_156_161,TEM-1,beta-lactamase_156,P62593,0.909407,NO,161,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.891,-3.777,2.886,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.111618,0.000897697,0.909407 beta-lactamase_S2C,beta-lactamase_2,TEM-1,beta-lactamase,P62593,0.90946,NO,2,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.942,-4.61,2.668,,,,,,,2.36,,65.38,HPH,-2.02767,0.221079,0.00227352,0.90946 kka2_1:2_K175D,kka2_1:2_175,Kka2,kka2_1:2,P00552,0.909483,NO,175,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-2.897,-3.874,0.977,,0.579,H,A,1.3,0.51,15.629,15.629,71.59,HBH,-1.82333,0.295029,0.00693093,0.909483 beta-lactamase_2500_P255C,beta-lactamase_2500_255,TEM-1,beta-lactamase_2500,P62593,0.909514,NO,255,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.361275,0.00499612,0.909514 beta-lactamase_0_M184E,beta-lactamase_0_184,TEM-1,beta-lactamase_0,P62593,0.909527,NO,184,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.593,-3.708,2.115,,,H,A,0.55,-0.87,13.292,13.292,62.94,HHH,-1.41,0.0500837,0.00356019,0.909527 beta-lactamase_I3M,beta-lactamase_3,TEM-1,beta-lactamase,P62593,0.909571,NO,3,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-2.143,-1.981,-0.162,,,,,,,3.946,,93.01,PHP,-2.21633,0.221079,0.00349304,0.909571 beta-lactamase_0_G281Y,beta-lactamase_0_281,TEM-1,beta-lactamase_0,P62593,0.909642,NO,281,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.0500837,0.0406482,0.909642 beta-lactamase_G85M,beta-lactamase_85,TEM-1,beta-lactamase,P62593,0.909663,NO,85,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.011,-4.877,3.866,5.58951,0.805,T,l,0.23,1.7,1.468,,63.64,HOP,-1.68733,0.221079,0.00252173,0.909663 kka2_1:8_P109H,kka2_1:8_109,Kka2,kka2_1:8,P00552,0.909689,NO,109,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.412,-3.364,1.952,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.100394,0.0070929,0.909689 kka2_1:8_P109H,kka2_1:8_109,Kka2,kka2_1:8,P00552,0.909689,NO,109,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.412,-3.364,1.952,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.100394,0.0070929,0.909689 beta-lactamase_L47A,beta-lactamase_47,TEM-1,beta-lactamase,P62593,0.909703,NO,47,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.876,-3.301,1.425,5.27297,0.007,E,B,1.07,0.2,1.244,,67.83,AHA,-1.639,0.221079,0.00439844,0.909703 beta-lactamase_39_A211W,beta-lactamase_39_211,TEM-1,beta-lactamase_39,P62593,0.909762,NO,211,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.896,-5.506,3.61,,0.369,T,A,0.46,-0.69,1.419,,77.62,AHA,-1.94633,0.0495842,0.00648183,0.909762 kka2_1:4_A34C,kka2_1:4_34,Kka2,kka2_1:4,P00552,0.909766,NO,34,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.928,-4.523,3.595,,0.417,.,B,0.46,2.29,0.262,,52.27,AHH,-1.747,0.168804,0.00343484,0.909766 PSD95pdz3_S339K,PSD95pdz3_339,PSD95pdz3,PSD95pdz3,P31016,0.909797,NO,339,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.519,-2.914,1.395,5.34493,,,,,12.2167,,,,HPH,-1.55767,0.0758425,0.00084982,0.909797 kka2_1:4_A65F,kka2_1:4_65,Kka2,kka2_1:4,P00552,0.90982,NO,65,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.744,-4.347,2.603,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.168804,0.00709258,0.90982 kka2_1:8_L47S,kka2_1:8_47,Kka2,kka2_1:8,P00552,0.909862,NO,47,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.265,-3.626,2.361,,0.139,E,B,1.59,-0.86,5.086,,63.26,HHH,-1.77933,0.100394,0.00509386,0.909862 kka2_1:8_L47S,kka2_1:8_47,Kka2,kka2_1:8,P00552,0.909862,NO,47,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.265,-3.626,2.361,,0.139,E,B,1.59,-0.86,5.086,,63.26,HHH,-1.77933,0.100394,0.00509386,0.909862 kka2_1:8_R140L,kka2_1:8_140,Kka2,kka2_1:8,P00552,0.909862,NO,140,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.351,-3.517,2.166,,0.12,H,A,0.16,0.2,2.874,,53.03,BBH,-1.885,0.100394,0.00430167,0.909862 kka2_1:8_R140L,kka2_1:8_140,Kka2,kka2_1:8,P00552,0.909862,NO,140,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.351,-3.517,2.166,,0.12,H,A,0.16,0.2,2.874,,53.03,BBH,-1.885,0.100394,0.00430167,0.909862 beta-lactamase_0_L38S,beta-lactamase_0_38,TEM-1,beta-lactamase_0,P62593,0.909871,NO,38,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.343,-2.597,1.254,,0.088,H,A,0.55,0.2,13.556,13.556,64.34,PHO,-1.78033,0.0500837,0.00373244,0.909871 PSD95pdz3_P346L,PSD95pdz3_346,PSD95pdz3,PSD95pdz3,P31016,0.909903,NO,346,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.236,-3.265,2.029,5.02406,,,,,14.6629,,,,OOH,-1.18367,0.0758425,0.000758563,0.909903 Pab1_L186M,Pab1_186,Pab1,Pab1,P04147,0.909918,NO,186,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.783,-3.914,2.131,,,,,,,,,,HHP,-1.56967,0.175299,0.00154968,0.909918 beta-lactamase_0_G236E,beta-lactamase_0_236,TEM-1,beta-lactamase_0,P62593,0.909953,NO,236,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.784,-3.634,2.85,,0.241,,b,0.29,-0.59,3.506,,64.69,HOO,-1.025,0.0500837,0.00162372,0.909953 Pab1_N192Y,Pab1_192,Pab1,Pab1,P04147,0.909999,NO,192,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-1.079,-3.98,2.901,,0.619,T,l,,2.28,,,,HPO,-1.231,0.175299,0.000273498,0.909999 beta-lactamase_L38F,beta-lactamase_38,TEM-1,beta-lactamase,P62593,0.910016,NO,38,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.343,-3.81,2.467,5.23728,0.088,H,A,1.75,0.2,1.986,,64.34,PHO,-1.78033,0.221079,0.00373244,0.910016 beta-lactamase_2500_D113C,beta-lactamase_2500_113,TEM-1,beta-lactamase_2500,P62593,0.910029,NO,113,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.829,-5.156,3.327,,0.665,T,A,0.75,0.91,21.104,21.104,73.08,PAO,-1.703,0.361275,0.00474112,0.910029 beta-lactamase_2500_R189E,beta-lactamase_2500_189,TEM-1,beta-lactamase_2500,P62593,0.910056,NO,189,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.844,-2.256,0.412,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.361275,0.0050699,0.910056 beta-lactamase_E119S,beta-lactamase_119,TEM-1,beta-lactamase,P62593,0.910064,NO,119,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.412,-2.681,1.269,5.33349,0.358,H,A,1.52,0.51,1.983,,63.99,BAH,-1.623,0.221079,0.00386966,0.910064 beta-lactamase_Q204D,beta-lactamase_204,TEM-1,beta-lactamase,P62593,0.910064,NO,204,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-1.382,-3.553,2.171,5.46394,0.204,H,A,0.12,0.09,1.707,,66.08,PPH,-1.49067,0.221079,0.00364106,0.910064 beta-lactamase_2500_T264M,beta-lactamase_2500_264,TEM-1,beta-lactamase_2500,P62593,0.910065,NO,264,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.361275,0.0119399,0.910065 kka2_1:2_F171Y,kka2_1:2_171,Kka2,kka2_1:2,P00552,0.910086,NO,171,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.326,-2.217,0.891,,0.154,H,A,0.58,-0.1,2.645,,63.64,HHH,-1.45433,0.295029,0.00821426,0.910086 beta-lactamase_2500_G194R,beta-lactamase_2500_194,TEM-1,beta-lactamase_2500,P62593,0.910144,NO,194,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.396,-3.912,2.516,,0.276,S,b,0.29,0.36,3.593,,67.83,POA,-1.832,0.361275,0.00392163,0.910144 kka2_1:1_L232P,kka2_1:1_232,Kka2,kka2_1:1,P00552,0.910154,NO,232,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.514,-4.306,2.792,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.520039,0.00800103,0.910154 beta-lactamase_0_L223Q,beta-lactamase_0_223,TEM-1,beta-lactamase_0,P62593,0.910167,NO,223,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.055,-4.184,3.129,,0.27,,B,0.55,0.09,1.633,,74.48,HHO,-1.35033,0.0500837,0.00372793,0.910167 beta-lactamase_F149L,beta-lactamase_149,TEM-1,beta-lactamase,P62593,0.910174,NO,149,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.299,-3.137,1.838,5.54789,0.195,H,A,1.1,0.11,1.863,,63.99,HHH,-1.46067,0.221079,0.00418462,0.910174 PSD95pdz3_A347G,PSD95pdz3_347,PSD95pdz3,PSD95pdz3,P31016,0.910177,NO,347,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.307,-2.59,1.283,4.89689,,,,,15.176,,,,OHA,-1.269,0.0758425,0.00074525,0.910177 PSD95pdz3_D357I,PSD95pdz3_357,PSD95pdz3,PSD95pdz3,P31016,0.910208,NO,357,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.264,-3.692,2.428,5.22306,,,,,10.975,,,,OAP,-1.32367,0.0758425,0.000609015,0.910208 beta-lactamase_0_T27H,beta-lactamase_0_27,TEM-1,beta-lactamase_0,P62593,0.910249,NO,27,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.905,-4.62,2.715,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.0500837,0.00306559,0.910249 beta-lactamase_156_W208Q,beta-lactamase_156_208,TEM-1,beta-lactamase_156,P62593,0.910286,NO,208,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-0.818,-4.124,3.306,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.111618,0.00126609,0.910286 beta-lactamase_39_A133F,beta-lactamase_39_133,TEM-1,beta-lactamase_39,P62593,0.910303,NO,133,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.186,-4.224,3.038,,,H,A,0.46,-0.86,0.373,,67.83,HHP,-0.988333,0.0495842,0.00468022,0.910303 beta-lactamase_F149A,beta-lactamase_149,TEM-1,beta-lactamase,P62593,0.910305,NO,149,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.299,-3.341,2.042,5.54789,0.195,H,A,1.1,0.11,1.863,,63.99,HHH,-1.46067,0.221079,0.00418462,0.910305 beta-lactamase_625_G52F,beta-lactamase_625_52,TEM-1,beta-lactamase_625,P62593,0.910313,NO,52,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.149,-4.393,3.244,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.213352,0.00340138,0.910313 kka2_1:8_R140V,kka2_1:8_140,Kka2,kka2_1:8,P00552,0.910316,NO,140,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.351,-3.736,2.385,,0.12,H,A,0.16,0.2,2.874,,53.03,BBH,-1.885,0.100394,0.00430167,0.910316 kka2_1:8_R140V,kka2_1:8_140,Kka2,kka2_1:8,P00552,0.910316,NO,140,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.351,-3.736,2.385,,0.12,H,A,0.16,0.2,2.874,,53.03,BBH,-1.885,0.100394,0.00430167,0.910316 beta-lactamase_625_T27H,beta-lactamase_625_27,TEM-1,beta-lactamase_625,P62593,0.910332,NO,27,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.905,-4.62,2.715,,0.007,H,A,0.22,-0.37,3.72,,93.01,APH,-1.97933,0.213352,0.00306559,0.910332 PSD95pdz3_T387D,PSD95pdz3_387,PSD95pdz3,PSD95pdz3,P31016,0.910339,NO,387,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.391,-3.15,1.759,5.20757,,,,,18.8043,,,,HPH,-1.49533,0.0758425,0.000167911,0.910339 beta-lactamase_2500_R92F,beta-lactamase_2500_92,TEM-1,beta-lactamase_2500,P62593,0.910353,NO,92,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.718,-4.33,2.612,,0.479,E,B,1.2,1.36,3.069,,65.38,BBH,-1.50367,0.361275,0.00429626,0.910353 PSD95pdz3_E331G,PSD95pdz3_331,PSD95pdz3,PSD95pdz3,P31016,0.910383,NO,331,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.404,-3.04,1.636,5.86289,,,,,51.8889,,,,OAA,-1.22533,0.0758425,0.000950134,0.910383 beta-lactamase_0_G52D,beta-lactamase_0_52,TEM-1,beta-lactamase_0,P62593,0.910407,NO,52,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.149,-2.123,0.974,,0.299,,l,0.29,-0.04,1.164,,64.69,POB,-1.66267,0.0500837,0.00340138,0.910407 beta-lactamase_0_P165S,beta-lactamase_0_165,TEM-1,beta-lactamase_0,P62593,0.910432,NO,165,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.373,-3.19,1.817,,0.203,T,A,0.52,-0.31,3.242,,73.78,AOA,-1.359,0.0500837,0.00549538,0.910432 beta-lactamase_0_V78F,beta-lactamase_0_78,TEM-1,beta-lactamase_0,P62593,0.910433,NO,78,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.459,-3.883,2.424,,,H,A,0.44,-0.47,16.615,16.615,63.64,HHH,-1.17833,0.0500837,0.00492501,0.910433 beta-lactamase_2500_I229V,beta-lactamase_2500_229,TEM-1,beta-lactamase_2500,P62593,0.910449,NO,229,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.267,-1.684,0.417,,0.083,E,B,0.48,-0.76,3.875,,50,HHH,-1.58767,0.361275,0.00477249,0.910449 PSD95pdz3_L379M,PSD95pdz3_379,PSD95pdz3,PSD95pdz3,P31016,0.910457,NO,379,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.347,-3.487,2.14,5.37777,,,,,16.8762,,,,HHB,-1.35667,0.0758425,0.00029733,0.910457 beta-lactamase_0_E46W,beta-lactamase_0_46,TEM-1,beta-lactamase_0,P62593,0.910481,NO,46,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.94,-5.418,3.478,,0.021,E,B,1.04,0.14,30.306,30.306,59.44,HAH,-2.079,0.0500837,0.00427568,0.910481 beta-lactamase_2500_K30L,beta-lactamase_2500_30,TEM-1,beta-lactamase_2500,P62593,0.910488,NO,30,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-2.307,-3.404,1.097,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.361275,0.00448593,0.910488 kka2_1:2_T72A,kka2_1:2_72,Kka2,kka2_1:2,P00552,0.910541,NO,72,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.38,-2.118,-0.262,,0.784,H,A,0.82,0.29,6.463,,65.53,HPP,-2.238,0.295029,0.00750756,0.910541 beta-lactamase_0_R159S,beta-lactamase_0_159,TEM-1,beta-lactamase_0,P62593,0.910548,NO,159,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-0.94,-3.411,2.471,,0.316,,B,1.2,-0.55,1.426,,64.34,PBH,-1.011,0.0500837,0.00108472,0.910548 beta-lactamase_2500_S233G,beta-lactamase_2500_233,TEM-1,beta-lactamase_2500,P62593,0.910566,NO,233,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.886,-3.274,1.388,,0.016,E,B,0.27,-1.01,2.851,,77.62,BPO,-1.17267,0.361275,0.00311415,0.910566 Pab1_S155N,Pab1_155,Pab1,Pab1,P04147,0.91063,NO,155,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.039,-3.725,1.686,,,,,,,,,,PPB,-1.42267,0.175299,0.00208179,0.91063 kka2_1:1_I2W,kka2_1:1_2,Kka2,kka2_1:1,P00552,0.910656,NO,2,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.787,-5.093,3.306,,,,,,,2.329,,71.59,HHA,-1.92433,0.520039,0.00246644,0.910656 beta-lactamase_A123C,beta-lactamase_123,TEM-1,beta-lactamase,P62593,0.910657,NO,123,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.834,-4.461,3.627,4.70061,0.039,H,A,0.52,-0.72,0.705,,41.26,PHH,-1.47367,0.221079,0.0010157,0.910657 beta-lactamase_E195C,beta-lactamase_195,TEM-1,beta-lactamase,P62593,0.910657,NO,195,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.186,-5.238,3.052,7.28489,1.016,S,A,1.52,0.85,2.583,,77.62,OAH,-2.02,0.221079,0.00496565,0.910657 beta-lactamase_F6W,beta-lactamase_6,TEM-1,beta-lactamase,P62593,0.910657,NO,6,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.847,-4.918,3.071,,,,,,,1.276,,67.83,BHB,-2.076,0.221079,0.00261627,0.910657 beta-lactamase_H5I,beta-lactamase_5,TEM-1,beta-lactamase,P62593,0.910657,NO,5,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-2.698,-2.831,0.133,,,,,,,1.865,,72.73,PBH,-2.36967,0.221079,0.00292712,0.910657 beta-lactamase_I54W,beta-lactamase_54,TEM-1,beta-lactamase,P62593,0.910657,NO,54,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-2.838,-5.452,2.614,5.40541,0.669,E,B,0.77,-0.14,3.946,,73.78,BHH,-2.337,0.221079,0.00403589,0.910657 beta-lactamase_R81M,beta-lactamase_81,TEM-1,beta-lactamase,P62593,0.910657,NO,81,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.466,-4.579,3.113,5.12166,0.218,H,A,0.68,1.66,1.236,,50,PBH,-1.60667,0.221079,0.00499763,0.910657 beta-lactamase_0_M270E,beta-lactamase_0_270,TEM-1,beta-lactamase_0,P62593,0.910664,NO,270,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.723,-4.709,2.986,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.0500837,0.00767762,0.910664 beta-lactamase_625_L197Y,beta-lactamase_625_197,TEM-1,beta-lactamase_625,P62593,0.910673,NO,197,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.853,-3.986,3.133,,0.007,S,B,0.55,0.33,1.756,,60.14,HHP,-1.833,0.213352,0.00144602,0.910673 beta-lactamase_625_G141T,beta-lactamase_625_141,TEM-1,beta-lactamase_625,P62593,0.910691,NO,141,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.828,-3.647,2.819,,0.575,T,l,0.29,-0.28,0.198,,64.69,HOO,-1.08933,0.213352,0.0012419,0.910691 PSD95pdz3_N326L,PSD95pdz3_326,PSD95pdz3,PSD95pdz3,P31016,0.910694,NO,326,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-1.41,-3.265,1.855,5.52537,,,,,19.0688,,,,HPH,-1.52133,0.0758425,0.00101078,0.910694 beta-lactamase_0_H156W,beta-lactamase_0_156,TEM-1,beta-lactamase_0,P62593,0.910751,NO,156,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-3.156,-5.55,2.394,,0.753,S,A,0.17,-0.6,23.367,23.367,77.62,ABH,-1.932,0.0500837,0.00468596,0.910751 kka2_1:1_G6E,kka2_1:1_6,Kka2,kka2_1:1,P00552,0.910779,NO,6,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.685,-3.379,1.694,,,,,,,1.292,,71.59,AOH,-1.639,0.520039,0.00204693,0.910779 kka2_1:1_L158W,kka2_1:1_158,Kka2,kka2_1:1,P00552,0.910779,NO,158,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.947,-4.75,2.803,,0.095,.,B,0.55,0.77,7.588,,63.64,AHA,-1.25333,0.520039,0.00529068,0.910779 beta-lactamase_0_S57N,beta-lactamase_0_57,TEM-1,beta-lactamase_0,P62593,0.910824,NO,57,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.918,-2.953,1.035,,0.352,E,B,0.27,-0.18,1.454,,72.73,APH,-2.29167,0.0500837,0.00492804,0.910824 beta-lactamase_0_H156D,beta-lactamase_0_156,TEM-1,beta-lactamase_0,P62593,0.910835,NO,156,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-3.156,-2.458,-0.698,,0.753,S,A,0.17,-0.6,23.367,23.367,77.62,ABH,-1.932,0.0500837,0.00468596,0.910835 beta-lactamase_0_M270P,beta-lactamase_0_270,TEM-1,beta-lactamase_0,P62593,0.91089,NO,270,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.0500837,0.00767762,0.91089 beta-lactamase_2500_I285T,beta-lactamase_2500_285,TEM-1,beta-lactamase_2500,P62593,0.910919,NO,285,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.361275,0.101555,0.910919 beta-lactamase_625_R257M,beta-lactamase_625_257,TEM-1,beta-lactamase_625,P62593,0.910946,NO,257,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.213352,0.00756629,0.910946 beta-lactamase_0_G249R,beta-lactamase_0_249,TEM-1,beta-lactamase_0,P62593,0.910963,NO,249,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.0500837,0.00220169,0.910963 beta-lactamase_0_M67R,beta-lactamase_0_67,TEM-1,beta-lactamase_0,P62593,0.910965,NO,67,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-2.231,-3.989,1.758,,0.006,G,P,0.55,-0.81,24.165,24.165,65.03,HHP,-1.502,0.0500837,0.00409753,0.910965 kka2_1:1_A71S,kka2_1:1_71,Kka2,kka2_1:1,P00552,0.91097,NO,71,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.824,-2.597,0.773,,0.553,H,A,0.46,0.08,9.788,,64.39,HHP,-1.74033,0.520039,0.00727707,0.91097 kka2_1:8_D52W,kka2_1:8_52,Kka2,kka2_1:8,P00552,0.910988,NO,52,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.271,-5.394,3.123,,0.22,E,B,0.75,0.8,5.447,,71.59,PAH,-2.38367,0.100394,0.00175694,0.910988 kka2_1:8_D52W,kka2_1:8_52,Kka2,kka2_1:8,P00552,0.910988,NO,52,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.271,-5.394,3.123,,0.22,E,B,0.75,0.8,5.447,,71.59,PAH,-2.38367,0.100394,0.00175694,0.910988 PSD95pdz3_E331L,PSD95pdz3_331,PSD95pdz3,PSD95pdz3,P31016,0.911024,NO,331,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.404,-3.265,1.861,5.86289,,,,,51.8889,,,,OAA,-1.22533,0.0758425,0.000950134,0.911024 beta-lactamase_A170R,beta-lactamase_170,TEM-1,beta-lactamase,P62593,0.911084,NO,170,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.237,-3.908,2.671,5.19261,0.126,,L,2.34,-0.35,2.427,,64.69,AHH,-1.63267,0.221079,0.00431903,0.911084 beta-lactamase_625_L135C,beta-lactamase_625_135,TEM-1,beta-lactamase_625,P62593,0.911087,NO,135,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.002,-4.691,3.689,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.213352,0.00244423,0.911087 kka2_1:2_G10W,kka2_1:2_10,Kka2,kka2_1:2,P00552,0.9111,NO,10,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.921,-5.359,3.438,,,,,,,2.192,,71.59,HOP,-2.10733,0.295029,0.00289233,0.9111 beta-lactamase_2500_P217S,beta-lactamase_2500_217,TEM-1,beta-lactamase_2500,P62593,0.911106,NO,217,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-2.062,-2.615,0.553,,0.496,I,A,0.52,-0.33,0.431,,74.48,OOH,-1.64333,0.361275,0.00463211,0.911106 beta-lactamase_H5R,beta-lactamase_5,TEM-1,beta-lactamase,P62593,0.911122,NO,5,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-2.698,-2.835,0.137,,,,,,,1.865,,72.73,PBH,-2.36967,0.221079,0.00292712,0.911122 kka2_1:8_G55K,kka2_1:8_55,Kka2,kka2_1:8,P00552,0.911157,NO,55,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.625,-3.726,2.101,,0.517,S,b,0.29,1.19,8.881,,63.64,POH,-2.05967,0.100394,0.00667877,0.911157 kka2_1:8_G55K,kka2_1:8_55,Kka2,kka2_1:8,P00552,0.911157,NO,55,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.625,-3.726,2.101,,0.517,S,b,0.29,1.19,8.881,,63.64,POH,-2.05967,0.100394,0.00667877,0.911157 beta-lactamase_M127K,beta-lactamase_127,TEM-1,beta-lactamase,P62593,0.911185,NO,127,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-2.251,-3,0.749,5.40552,0.312,S,A,1.07,0.32,1.671,,72.73,PHP,-1.40433,0.221079,0.00437927,0.911185 kka2_1:4_S54I,kka2_1:4_54,Kka2,kka2_1:4,P00552,0.91121,NO,54,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.471,-2.562,0.091,,0.408,S,b,0.27,1.01,17.332,17.332,71.59,HPO,-2.259,0.168804,0.00782867,0.91121 gb1_T270I,gb1_270,gb1,gb1,P06654,0.911234,NO,270,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-3.15,-3.578,0.428,,,,,,,1.326,,45.54,HPH,-1.843,0.177985,0.00223707,0.911234 beta-lactamase_39_E195W,beta-lactamase_39_195,TEM-1,beta-lactamase_39,P62593,0.911235,NO,195,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.186,-5.555,3.369,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.0495842,0.00496565,0.911235 beta-lactamase_39_K213M,beta-lactamase_39_213,TEM-1,beta-lactamase_39,P62593,0.911252,NO,213,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.81,-4.653,2.843,,0.67,,A,2.34,0.29,2.648,,67.83,ABH,-1.57767,0.0495842,0.00610411,0.911252 Ubiquitin_D32N,Ubiquitin_32,Uba1,Ubiquitin,P0CG48,0.91129,NO,32,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.451,-2.442,0.991,4.96502,0.835,H,A,,1.4,,,,PAB,-1.47067,0.205827,0.000758819,0.91129 Ubiquitin_D58K,Ubiquitin_58,Uba1,Ubiquitin,P0CG48,0.91129,NO,58,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.622,-3.591,1.969,5.06391,0.457,G,A,,-0.54,,,,PAH,-1.60267,0.205827,0.000639847,0.91129 Ubiquitin_F45Q,Ubiquitin_45,Uba1,Ubiquitin,P0CG48,0.91129,NO,45,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.322,-4.266,2.944,4.80693,0.26,E,B,1.62,-0.99,1.531,,53.87,HHH,-1.55267,0.205827,0.000470401,0.91129 Ubiquitin_G35Q,Ubiquitin_35,Uba1,Ubiquitin,P0CG48,0.91129,NO,35,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.171,-3.93,2.759,4.96213,0.713,,L,,0.2,,,,AOH,-1.314,0.205827,0.000648878,0.91129 Ubiquitin_I30C,Ubiquitin_30,Uba1,Ubiquitin,P0CG48,0.91129,NO,30,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.205,-4.663,3.458,4.80264,,H,A,,-0.51,,,,BHP,-1.45133,0.205827,0.000720128,0.91129 Ubiquitin_I30F,Ubiquitin_30,Uba1,Ubiquitin,P0CG48,0.91129,NO,30,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.205,-3.709,2.504,4.80264,,H,A,,-0.51,,,,BHP,-1.45133,0.205827,0.000720128,0.91129 Ubiquitin_K33E,Ubiquitin_33,Uba1,Ubiquitin,P0CG48,0.91129,NO,33,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.283,-3.298,2.015,5.08526,0.64,H,A,1.82,1.2,1.509,,51.09,ABA,-1.34267,0.205827,0.000712743,0.91129 Ubiquitin_K33R,Ubiquitin_33,Uba1,Ubiquitin,P0CG48,0.91129,NO,33,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.283,-2.362,1.079,5.08526,0.64,H,A,1.82,1.2,1.509,,51.09,ABA,-1.34267,0.205827,0.000712743,0.91129 Ubiquitin_N60M,Ubiquitin_60,Uba1,Ubiquitin,P0CG48,0.91129,NO,60,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-1.775,-4.739,2.964,5.00332,0.775,T,L,,0.33,,,,HPH,-1.532,0.205827,0.000814061,0.91129 Ubiquitin_Q49N,Ubiquitin_49,Uba1,Ubiquitin,P0CG48,0.91129,NO,49,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-1.941,-3.741,1.8,5.05026,0.403,E,B,,-0.59,,,,BPH,-1.49467,0.205827,0.000613067,0.91129 Ubiquitin_T22L,Ubiquitin_22,Uba1,Ubiquitin,P0CG48,0.91129,NO,22,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.344,-3.187,1.843,4.54389,0.237,B,B,,-0.75,,,,APH,-1.28733,0.205827,0.000535592,0.91129 Ubiquitin_T66G,Ubiquitin_66,Uba1,Ubiquitin,P0CG48,0.91129,NO,66,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.58,-2.743,1.163,5.02702,0.46,E,B,0.8,-0.81,28.36,28.36,39.71,PPH,-1.51667,0.205827,0.000598414,0.91129 Ubiquitin_V26A,Ubiquitin_26,Uba1,Ubiquitin,P0CG48,0.91129,NO,26,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.321,-3.031,1.71,4.78447,,H,A,,-0.97,,,,PHB,-1.445,0.205827,0.000980269,0.91129 Ubiquitin_Y59M,Ubiquitin_59,Uba1,Ubiquitin,P0CG48,0.91129,NO,59,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-1.307,-4.549,3.242,5.05599,0.072,G,A,0.43,-0.74,2.566,,24.53,AHP,-1.568,0.205827,0.000775084,0.91129 beta-lactamase_2500_L28W,beta-lactamase_2500_28,TEM-1,beta-lactamase_2500,P62593,0.911291,NO,28,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.579,-5.332,3.753,,0.277,H,A,0.55,-0.16,2.716,,93.01,PHH,-2.11333,0.361275,0.00359321,0.911291 kka2_1:4_G201K,kka2_1:4_201,Kka2,kka2_1:4,P00552,0.911348,NO,201,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.56,-2.796,1.236,,0.149,T,l,0.29,-0.57,0.284,,52.65,POB,-1.92233,0.168804,0.00820117,0.911348 kka2_1:8_L39A,kka2_1:8_39,Kka2,kka2_1:8,P00552,0.911372,NO,39,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.223,-2.615,1.392,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.100394,0.00493618,0.911372 kka2_1:8_L39A,kka2_1:8_39,Kka2,kka2_1:8,P00552,0.911372,NO,39,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.223,-2.615,1.392,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.100394,0.00493618,0.911372 beta-lactamase_H24C,beta-lactamase_24,TEM-1,beta-lactamase,P62593,0.911381,NO,24,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-2.481,-4.897,2.416,5.82767,,,,,,2.708,,93.01,HBO,-1.85167,0.221079,0.00238894,0.911381 kka2_1:1_I196V,kka2_1:1_196,Kka2,kka2_1:1,P00552,0.911386,NO,196,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-2.115,-2.455,0.34,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.520039,0.0107273,0.911386 kka2_1:2_E231L,kka2_1:2_231,Kka2,kka2_1:2,P00552,0.911436,NO,231,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.002,-3.642,1.64,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.295029,0.00732383,0.911436 beta-lactamase_0_R176Y,beta-lactamase_0_176,TEM-1,beta-lactamase_0,P62593,0.911464,NO,176,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-0.863,-4.162,3.299,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.0500837,0.00105554,0.911464 beta-lactamase_2500_A278C,beta-lactamase_2500_278,TEM-1,beta-lactamase_2500,P62593,0.911465,NO,278,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.361275,0.0310297,0.911465 kka2_1:1_V36G,kka2_1:1_36,Kka2,kka2_1:1,P00552,0.911479,NO,36,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-0.898,-3.694,2.796,,0.292,E,B,0.44,0.21,0.278,,52.27,HHH,-1.484,0.520039,0.00245633,0.911479 kka2_1:8_A34S,kka2_1:8_34,Kka2,kka2_1:8,P00552,0.911479,NO,34,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.928,-1.892,0.964,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.100394,0.00343484,0.911479 kka2_1:8_A34S,kka2_1:8_34,Kka2,kka2_1:8,P00552,0.911479,NO,34,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.928,-1.892,0.964,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.100394,0.00343484,0.911479 beta-lactamase_0_M66F,beta-lactamase_0_66,TEM-1,beta-lactamase_0,P62593,0.911487,NO,66,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.362,-3.731,2.369,,0.013,,A,0.55,-0.7,1.204,,73.08,OHH,-1.49567,0.0500837,0.00412876,0.911487 beta-lactamase_625_L49P,beta-lactamase_625_49,TEM-1,beta-lactamase_625,P62593,0.911514,NO,49,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.897,-2.49,0.593,,0.131,T,A,0.55,0.04,3.112,,64.69,AHP,-1.99233,0.213352,0.00401477,0.911514 Pab1_M189R,Pab1_189,Pab1,Pab1,P04147,0.911538,NO,189,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.406,-3.525,2.119,,0.631,E,b,,2.81,,,,OHH,-1.18,0.175299,0.000278756,0.911538 beta-lactamase_Q4V,beta-lactamase_4,TEM-1,beta-lactamase,P62593,0.911545,NO,4,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,,-2.536,-0.028,,,,,,,,,,HPB,,0.221079,0.00316562,0.911545 hsp90_F583L,hsp90_583,hsp90,hsp90,P02829,0.911558,NO,583,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-3.22,-2.511,0,5.28185,1.112,S,l,1.1,0.87,,,,PHO,-3.003,0.368192,0.000222939,0.911558 PSD95pdz3_F325I,PSD95pdz3_325,PSD95pdz3,PSD95pdz3,P31016,0.911573,NO,325,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.524,-3.017,1.493,5.50654,,,,,12.7236,,,,OHP,-1.314,0.0758425,0.00102273,0.911573 kka2_1:4_Q4Y,kka2_1:4_4,Kka2,kka2_1:4,P00552,0.911597,NO,4,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.361,-4.04,1.679,,,,,,,2.026,,71.59,APA,-1.95533,0.168804,0.00239179,0.911597 kka2_1:2_G95E,kka2_1:2_95,Kka2,kka2_1:2,P00552,0.911598,NO,95,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-2.403,-2.685,0.282,,0.126,E,B,0.29,-0.74,0.359,,71.59,HOA,-2.198,0.295029,0.00743616,0.911598 beta-lactamase_0_A278T,beta-lactamase_0_278,TEM-1,beta-lactamase_0,P62593,0.911615,NO,278,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.348,,,,0.015,H,A,0.48,-0.85,4.624,,63.29,HHA,-1.41833,0.0500837,0.0310297,0.911615 Pab1_A182G,Pab1_182,Pab1,Pab1,P04147,0.911624,NO,182,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.013,-2.725,1.712,,,H,A,0.17,0.79,,,,AHH,-1.36067,0.175299,0.000289034,0.911624 beta-lactamase_0_D231P,beta-lactamase_0_231,TEM-1,beta-lactamase_0,P62593,0.911627,NO,231,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.816,-3.68,2.864,,,E,B,0.75,-1.06,4.975,,65.38,HAB,-0.994,0.0500837,0.00107395,0.911627 beta-lactamase_0_L49M,beta-lactamase_0_49,TEM-1,beta-lactamase_0,P62593,0.911634,NO,49,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.897,-4.411,2.514,,0.131,T,A,0.55,0.04,13.838,13.838,64.69,AHP,-1.99233,0.0500837,0.00401477,0.911634 beta-lactamase_39_G234Y,beta-lactamase_39_234,TEM-1,beta-lactamase_39,P62593,0.911645,NO,234,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.62,-4.387,3.767,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.0495842,0.000889577,0.911645 beta-lactamase_0_G39E,beta-lactamase_0_39,TEM-1,beta-lactamase_0,P62593,0.91168,NO,39,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.864,-2.833,0.969,,0.701,T,L,0.29,0.47,4.111,,77.62,HOH,-1.53633,0.0500837,0.00487611,0.91168 beta-lactamase_39_I229R,beta-lactamase_39_229,TEM-1,beta-lactamase_39,P62593,0.911713,NO,229,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.267,-4.174,2.907,,0.083,E,B,0.48,-0.76,1.114,,50,HHH,-1.58767,0.0495842,0.00477249,0.911713 beta-lactamase_2500_L188T,beta-lactamase_2500_188,TEM-1,beta-lactamase_2500,P62593,0.911716,NO,188,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.166,-3.522,2.356,,,H,A,0.55,-0.3,17.865,17.865,60.14,PHB,-1.47033,0.361275,0.00295687,0.911716 beta-lactamase_0_P224T,beta-lactamase_0_224,TEM-1,beta-lactamase_0,P62593,0.911736,NO,224,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.893,-3.414,2.521,,0.383,,B,0.52,-0.3,3.587,,74.48,HOH,-1.26433,0.0500837,0.00189564,0.911736 kka2_1:4_Q27H,kka2_1:4_27,Kka2,kka2_1:4,P00552,0.91175,NO,27,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-1.659,-4.651,2.992,,0.608,,A,0.4,0.71,1.498,,65.53,PPP,-1.90733,0.168804,0.00595365,0.91175 beta-lactamase_625_Y103C,beta-lactamase_625_103,TEM-1,beta-lactamase_625,P62593,0.911755,NO,103,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-1.33,-5.047,3.717,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.213352,0.00443048,0.911755 gb1_F256C,gb1_256,gb1,gb1,P06654,0.911791,NO,256,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.241,-4.639,3.398,,,,,,,,,,HHB,-2.04767,0.177985,0.00435993,0.911791 beta-lactamase_0_P165D,beta-lactamase_0_165,TEM-1,beta-lactamase_0,P62593,0.911831,NO,165,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.373,-3.54,2.167,,0.203,T,A,0.52,-0.31,3.242,,73.78,AOA,-1.359,0.0500837,0.00549538,0.911831 beta-lactamase_S254F,beta-lactamase_254,TEM-1,beta-lactamase,P62593,0.911861,NO,254,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.126,-4.422,2.296,5.49575,0.312,,a,0.25,-0.48,24.91,24.91,69.58,OPB,-2.215,0.221079,0.00369,0.911861 beta-lactamase_0_P250G,beta-lactamase_0_250,TEM-1,beta-lactamase_0,P62593,0.911887,NO,250,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.0500837,0.00550899,0.911887 kka2_1:2_W24F,kka2_1:2_24,Kka2,kka2_1:2,P00552,0.911895,NO,24,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-1.779,-2.325,0.546,,0.477,E,B,1.51,-0.21,2.666,,56.06,AHH,-2.24467,0.295029,0.00631564,0.911895 beta-lactamase_2500_I54A,beta-lactamase_2500_54,TEM-1,beta-lactamase_2500,P62593,0.91196,NO,54,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-2.838,-2.597,-0.241,,0.669,E,B,0.48,-0.14,3.946,,73.78,BHH,-2.337,0.361275,0.00403589,0.91196 kka2_1:8_D157K,kka2_1:8_157,Kka2,kka2_1:8,P00552,0.911974,NO,157,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.993,-3.506,2.513,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.100394,0.0042313,0.911974 kka2_1:8_D157K,kka2_1:8_157,Kka2,kka2_1:8,P00552,0.911974,NO,157,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.993,-3.506,2.513,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.100394,0.0042313,0.911974 hsp90_M589T,hsp90_589,hsp90,hsp90,P02829,0.911991,NO,589,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-3.858,-2.8,0,4.72723,0.032,H,A,0.84,0.31,,,,PHA,-3.24233,0.368192,0.000222939,0.911991 kka2_1:8_T187V,kka2_1:8_187,Kka2,kka2_1:8,P00552,0.911995,NO,187,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.273,-3.25,1.977,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.100394,0.00693073,0.911995 kka2_1:8_T187V,kka2_1:8_187,Kka2,kka2_1:8,P00552,0.911995,NO,187,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.273,-3.25,1.977,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.100394,0.00693073,0.911995 kka2_1:1_L60R,kka2_1:1_60,Kka2,kka2_1:1,P00552,0.911996,NO,60,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.997,-4.088,3.091,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.520039,0.00262176,0.911996 beta-lactamase_625_G114Y,beta-lactamase_625_114,TEM-1,beta-lactamase_625,P62593,0.912002,NO,114,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.094,-4.391,3.297,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.213352,0.00224919,0.912002 kka2_1:2_Q252G,kka2_1:2_252,Kka2,kka2_1:2,P00552,0.912011,NO,252,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.63,-2.545,-0.085,,0.906,H,A,0.64,0.35,5.613,,92.05,PPB,-2.20733,0.295029,0.0121001,0.912011 kka2_1:4_L93V,kka2_1:4_93,Kka2,kka2_1:4,P00552,0.912042,NO,93,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.815,-2.967,2.152,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.168804,0.00131498,0.912042 beta-lactamase_0_L167Q,beta-lactamase_0_167,TEM-1,beta-lactamase_0,P62593,0.912048,NO,167,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.138,-4.038,2.9,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.0500837,0.00303566,0.912048 gb1_Y229A,gb1_229,gb1,gb1,P06654,0.91207,NO,229,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-1.282,-3.038,1.756,,,,,,,,,,PHB,-1.4915,0.177985,0.00366605,0.91207 PSD95pdz3_L367V,PSD95pdz3_367,PSD95pdz3,PSD95pdz3,P31016,0.912071,NO,367,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.347,-2.535,1.188,5.47696,,,,,17.0063,,,,AHB,-1.39767,0.0758425,0.000466436,0.912071 beta-lactamase_0_L79R,beta-lactamase_0_79,TEM-1,beta-lactamase_0,P62593,0.912074,NO,79,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.842,-3.93,3.088,,0.007,H,A,0.55,-0.16,5.053,,50.35,HHP,-1.44333,0.0500837,0.000947397,0.912074 beta-lactamase_0_S51R,beta-lactamase_0_51,TEM-1,beta-lactamase_0,P62593,0.912116,NO,51,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.526,-2.956,1.43,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.0500837,0.00504821,0.912116 kka2_1:2_Q61F,kka2_1:2_61,Kka2,kka2_1:2,P00552,0.91214,NO,61,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.982,-4.457,1.475,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.295029,0.00612092,0.91214 beta-lactamase_F149T,beta-lactamase_149,TEM-1,beta-lactamase,P62593,0.91216,NO,149,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.299,-3.669,2.37,5.54789,0.195,H,A,1.1,0.11,1.863,,63.99,HHH,-1.46067,0.221079,0.00418462,0.91216 beta-lactamase_0_L223F,beta-lactamase_0_223,TEM-1,beta-lactamase_0,P62593,0.912162,NO,223,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.055,-2.724,1.669,,0.27,,B,0.55,0.09,1.633,,74.48,HHO,-1.35033,0.0500837,0.00372793,0.912162 beta-lactamase_0_G234N,beta-lactamase_0_234,TEM-1,beta-lactamase_0,P62593,0.912197,NO,234,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.62,-3.448,2.828,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.0500837,0.000889577,0.912197 beta-lactamase_0_R59C,beta-lactamase_0_59,TEM-1,beta-lactamase_0,P62593,0.912229,NO,59,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.345,-2.854,1.509,,0.329,S,L,1.2,-0.09,2.919,,73.08,HBO,-2.24267,0.0500837,0.00318082,0.912229 beta-lactamase_0_G39P,beta-lactamase_0_39,TEM-1,beta-lactamase_0,P62593,0.912231,NO,39,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.864,-3.073,1.209,,0.701,T,L,0.29,0.47,4.111,,77.62,HOH,-1.53633,0.0500837,0.00487611,0.912231 beta-lactamase_2500_M180F,beta-lactamase_2500_180,TEM-1,beta-lactamase_2500,P62593,0.912261,NO,180,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-2.795,-3.981,1.186,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.361275,0.00552048,0.912261 beta-lactamase_2500_G243A,beta-lactamase_2500_243,TEM-1,beta-lactamase_2500,P62593,0.912263,NO,243,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.361275,0.00464034,0.912263 beta-lactamase_H94C,beta-lactamase_94,TEM-1,beta-lactamase,P62593,0.912286,NO,94,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-2.5,-5.143,2.643,6.1507,0.776,,B,0.63,1.24,1.176,,77.62,HBH,-1.872,0.221079,0.00389226,0.912286 gb1_N263C,gb1_263,gb1,gb1,P06654,0.912347,NO,263,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-1.162,-4.864,3.702,,,,,,,,,,APO,-2.04233,0.177985,0.0035297,0.912347 beta-lactamase_0_P217D,beta-lactamase_0_217,TEM-1,beta-lactamase_0,P62593,0.912395,NO,217,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-2.062,-2.498,0.436,,0.496,I,A,0.52,-0.33,1.087,,74.48,OOH,-1.64333,0.0500837,0.00463211,0.912395 beta-lactamase_0_S96G,beta-lactamase_0_96,TEM-1,beta-lactamase_0,P62593,0.912416,NO,96,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.27,-2.481,0.211,,0.368,,b,0.27,0.39,2.516,,73.78,HPP,-2.019,0.0500837,0.00551835,0.912416 beta-lactamase_0_F228D,beta-lactamase_0_228,TEM-1,beta-lactamase_0,P62593,0.912423,NO,228,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-2.342,-3.807,1.465,,0.154,E,B,0.58,-0.42,15.504,15.504,63.29,HHH,-1.53033,0.0500837,0.0046669,0.912423 kka2_1:4_D118V,kka2_1:4_118,Kka2,kka2_1:4,P00552,0.912428,NO,118,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.07,-3.108,1.038,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.168804,0.0067852,0.912428 WW_domain_Q186D,WW_domain_186,Yap65,WW_domain,P46937,0.91243,NO,186,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-1.358,-3.021,1.663,4.88854,,,,,,,,,OPB,-1.207,0.153962,0.00161546,0.91243 beta-lactamase_V106Y,beta-lactamase_106,TEM-1,beta-lactamase,P62593,0.912434,NO,106,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.218,-3.895,2.677,5.23115,0.258,T,A,0.96,0.24,1.188,,72.73,OHP,-1.04933,0.221079,0.00304168,0.912434 kka2_1:2_G74E,kka2_1:2_74,Kka2,kka2_1:2,P00552,0.912442,NO,74,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.18,-2.749,1.569,,0.621,T,l,0.75,0.2,1.446,,64.39,POH,-1.91667,0.295029,0.00587035,0.912442 E1_Ubiquitin_H70F,E1_Ubiquitin_70,Uba1,E1_Ubiquitin,P0CG63,0.912467,NO,70,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-1.36,,,,0.05,E,B,0.61,-0.97,,,93.18,HBH,-1.146,0.18783,0.00206914,0.912467 beta-lactamase_2500_P255Y,beta-lactamase_2500_255,TEM-1,beta-lactamase_2500,P62593,0.912473,NO,255,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.361275,0.00499612,0.912473 beta-lactamase_L146I,beta-lactamase_146,TEM-1,beta-lactamase,P62593,0.912518,NO,146,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.462,-2.631,1.169,5.62483,0.007,H,A,1.3,-0.56,1.953,,64.69,AHP,-1.656,0.221079,0.00474542,0.912518 kka2_1:2_G95T,kka2_1:2_95,Kka2,kka2_1:2,P00552,0.912562,NO,95,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-2.403,-1.849,-0.554,,0.126,E,B,0.29,-0.74,0.359,,71.59,HOA,-2.198,0.295029,0.00743616,0.912562 kka2_1:4_L19T,kka2_1:4_19,Kka2,kka2_1:4,P00552,0.912585,NO,19,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.254,-3.645,2.391,,0.08,T,A,1.59,-0.26,2.645,,65.53,BHH,-2.221,0.168804,0.00620703,0.912585 Pab1_L153Y,Pab1_153,Pab1,Pab1,P04147,0.912615,NO,153,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.039,-3.755,2.716,,0.46,E,A,,-0.95,,,,HHP,-1.17667,0.175299,0.000321212,0.912615 kka2_1:8_V16W,kka2_1:8_16,Kka2,kka2_1:8,P00552,0.912618,NO,16,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-3.087,-5.53,2.443,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.100394,0.00694011,0.912618 kka2_1:8_V16W,kka2_1:8_16,Kka2,kka2_1:8,P00552,0.912618,NO,16,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-3.087,-5.53,2.443,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.100394,0.00694011,0.912618 beta-lactamase_0_N130W,beta-lactamase_0_130,TEM-1,beta-lactamase_0,P62593,0.91266,NO,130,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-0.798,-5.547,4.749,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.0500837,0.000683376,0.91266 beta-lactamase_E62Y,beta-lactamase_62,TEM-1,beta-lactamase,P62593,0.912714,NO,62,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.193,-4.285,3.092,5.93066,0.342,S,B,1.52,-0.3,3.139,,73.08,AAB,-1.417,0.221079,0.00264802,0.912714 beta-lactamase_G216C,beta-lactamase_216,TEM-1,beta-lactamase,P62593,0.912714,NO,216,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.477,-5.186,3.709,4.91694,0.437,I,A,0.23,-0.58,1.718,,74.48,HOO,-1.68067,0.221079,0.00639568,0.912714 beta-lactamase_39_M115P,beta-lactamase_39_115,TEM-1,beta-lactamase_39,P62593,0.912733,NO,115,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.389,-4.034,2.645,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.0495842,0.0034337,0.912733 beta-lactamase_2500_E102G,beta-lactamase_2500_102,TEM-1,beta-lactamase_2500,P62593,0.912794,NO,102,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.118,-2.728,0.61,,0.722,S,B,1.04,1.82,1.336,,73.08,HAH,-1.581,0.361275,0.00486633,0.912794 beta-lactamase_0_Q204N,beta-lactamase_0_204,TEM-1,beta-lactamase_0,P62593,0.91281,NO,204,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-1.382,-3.623,2.241,,0.204,H,A,0.64,0.09,2.646,,66.08,PPH,-1.49067,0.0500837,0.00364106,0.91281 beta-lactamase_0_R242F,beta-lactamase_0_242,TEM-1,beta-lactamase_0,P62593,0.912832,NO,242,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.0500837,0.00452879,0.912832 beta-lactamase_625_V214Y,beta-lactamase_625_214,TEM-1,beta-lactamase_625,P62593,0.912857,NO,214,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.299,-4.125,2.826,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.213352,0.00628442,0.912857 kka2_1:4_E96R,kka2_1:4_96,Kka2,kka2_1:4,P00552,0.912883,NO,96,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.573,-2.69,0.117,,0.476,,B,1.52,-0.65,1.254,,71.59,OAH,-2.143,0.168804,0.00369441,0.912883 gb1_K230D,gb1_230,gb1,gb1,P06654,0.912901,NO,230,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.701,-3.48,1.779,,,,,,,0.166,,11.83,HBH,-1.52867,0.177985,0.00331703,0.912901 beta-lactamase_2500_P217E,beta-lactamase_2500_217,TEM-1,beta-lactamase_2500,P62593,0.912923,NO,217,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-2.062,-2.651,0.589,,0.496,I,A,0.52,-0.33,0.431,,74.48,OOH,-1.64333,0.361275,0.00463211,0.912923 beta-lactamase_2500_A183F,beta-lactamase_2500_183,TEM-1,beta-lactamase_2500,P62593,0.912928,NO,183,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.231,-4.164,2.933,,0.155,H,A,0.46,-0.91,12.189,,77.62,HHH,-1.53367,0.361275,0.00296631,0.912928 kka2_1:8_P12Q,kka2_1:8_12,Kka2,kka2_1:8,P00552,0.912939,NO,12,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.853,-3.937,3.084,,,.,B,0.52,1.25,2.41,,48.11,POH,-1.80767,0.100394,0.00500011,0.912939 kka2_1:8_P12Q,kka2_1:8_12,Kka2,kka2_1:8,P00552,0.912939,NO,12,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.853,-3.937,3.084,,,.,B,0.52,1.25,2.41,,48.11,POH,-1.80767,0.100394,0.00500011,0.912939 PSD95pdz3_G345Y,PSD95pdz3_345,PSD95pdz3,PSD95pdz3,P31016,0.913,NO,345,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.008,-4.069,3.061,4.32868,,,,,13.165,,,,OOO,-1.084,0.0758425,0.000771806,0.913 beta-lactamase_0_D129E,beta-lactamase_0_129,TEM-1,beta-lactamase_0,P62593,0.91306,NO,129,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.816,-2.232,1.416,,,,B,0.75,-0.69,2.66,,34.97,PAP,-0.818,0.0500837,0.00109178,0.91306 beta-lactamase_0_R273W,beta-lactamase_0_273,TEM-1,beta-lactamase_0,P62593,0.913062,NO,273,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.314,-5.456,3.142,,0.564,H,A,1.2,1.57,20.248,20.248,73.78,ABP,-1.841,0.0500837,0.0077952,0.913062 kka2_1:8_F203M,kka2_1:8_203,Kka2,kka2_1:8,P00552,0.913067,NO,203,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-0.911,-4.239,3.328,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.100394,0.00318738,0.913067 kka2_1:8_F203M,kka2_1:8_203,Kka2,kka2_1:8,P00552,0.913067,NO,203,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-0.911,-4.239,3.328,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.100394,0.00318738,0.913067 kka2_1:2_L174A,kka2_1:2_174,Kka2,kka2_1:2,P00552,0.913087,NO,174,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.952,-2.507,1.555,,,H,A,1.59,-0.31,8.521,,51.89,BHB,-2.08533,0.295029,0.00438501,0.913087 beta-lactamase_2500_R159T,beta-lactamase_2500_159,TEM-1,beta-lactamase_2500,P62593,0.913141,NO,159,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-0.94,-3.47,2.53,,0.316,,B,1.2,-0.55,2.341,,64.34,PBH,-1.011,0.361275,0.00108472,0.913141 kka2_1:4_R147L,kka2_1:4_147,Kka2,kka2_1:4,P00552,0.913165,NO,147,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.123,-3.547,2.424,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.168804,0.00549168,0.913165 PSD95pdz3_A347V,PSD95pdz3_347,PSD95pdz3,PSD95pdz3,P31016,0.913199,NO,347,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.307,-2.76,1.453,4.89689,,,,,15.176,,,,OHA,-1.269,0.0758425,0.00074525,0.913199 beta-lactamase_0_V72C,beta-lactamase_0_72,TEM-1,beta-lactamase_0,P62593,0.913231,NO,72,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.658,-4.8,3.142,,,H,A,0.44,-1.03,2.964,,65.73,BHH,-1.32167,0.0500837,0.00501194,0.913231 kka2_1:2_L241R,kka2_1:2_241,Kka2,kka2_1:2,P00552,0.913241,NO,241,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.158,-4.121,2.963,,0.08,H,A,0.55,-0.82,1.598,,63.26,HHH,-1.58533,0.295029,0.0117299,0.913241 kka2_1:4_K138D,kka2_1:4_138,Kka2,kka2_1:4,P00552,0.913259,NO,138,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-2.5,-2.178,-0.322,,0.594,H,A,1.3,0.98,21.267,21.267,71.59,HBB,-2.48833,0.168804,0.00628542,0.913259 beta-lactamase_0_W288K,beta-lactamase_0_288,TEM-1,beta-lactamase_0,P62593,0.913266,NO,288,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,,,,,,,,,,,,,BHO,,0.0500837,,0.913266 beta-lactamase_39_T263D,beta-lactamase_39_263,TEM-1,beta-lactamase_39,P62593,0.913315,NO,263,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.0495842,0.0110582,0.913315 PSD95pdz3_I377K,PSD95pdz3_377,PSD95pdz3,PSD95pdz3,P31016,0.913318,NO,377,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.873,-3.581,1.708,4.9532,,,,,19.185,2.364,,87.71,HHH,-1.49567,0.0758425,0.000795475,0.913318 beta-lactamase_2500_L89I,beta-lactamase_2500_89,TEM-1,beta-lactamase_2500,P62593,0.913335,NO,89,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.096,-3.166,2.07,,0.168,T,A,0.55,0.63,2.066,,64.34,PHO,-1.75767,0.361275,0.00207068,0.913335 beta-lactamase_2500_E87F,beta-lactamase_2500_87,TEM-1,beta-lactamase_2500,P62593,0.913355,NO,87,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.421,-4.277,2.856,,0.048,,B,1.04,0.92,17.923,17.923,64.69,PAP,-1.969,0.361275,0.00337888,0.913355 beta-lactamase_0_L79E,beta-lactamase_0_79,TEM-1,beta-lactamase_0,P62593,0.91339,NO,79,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.842,-3.887,3.045,,0.007,H,A,0.55,-0.16,5.053,,50.35,HHP,-1.44333,0.0500837,0.000947397,0.91339 beta-lactamase_2500_P172G,beta-lactamase_2500_172,TEM-1,beta-lactamase_2500,P62593,0.913401,NO,172,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.998,-3.35,2.352,,0.639,T,b,0.52,0.24,4.99,,74.48,HOP,-2.03067,0.361275,0.00312594,0.913401 kka2_1:8_F264W,kka2_1:8_264,Kka2,kka2_1:8,P00552,0.913431,NO,264,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.02,-4.514,3.494,,0.296,,?,1.62,0.02,1.553,,71.59,HHO,-0.9655,0.100394,,0.913431 kka2_1:8_F264W,kka2_1:8_264,Kka2,kka2_1:8,P00552,0.913431,NO,264,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.02,-4.514,3.494,,0.296,,?,1.62,0.02,1.553,,71.59,HHO,-0.9655,0.100394,,0.913431 beta-lactamase_39_K213C,beta-lactamase_39_213,TEM-1,beta-lactamase_39,P62593,0.91344,NO,213,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.81,-5.208,3.398,,0.67,,A,2.34,0.29,2.648,,67.83,ABH,-1.57767,0.0495842,0.00610411,0.91344 beta-lactamase_E46H,beta-lactamase_46,TEM-1,beta-lactamase,P62593,0.913449,NO,46,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.94,-4.828,2.888,5.36461,0.021,E,B,1.51,0.14,0.373,,59.44,HAH,-2.079,0.221079,0.00427568,0.913449 beta-lactamase_P25P,beta-lactamase_25,TEM-1,beta-lactamase,P62593,0.913449,NO,25,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.526,-1.526,,5.6134,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.221079,0.00347571,0.913449 beta-lactamase_T116L,beta-lactamase_116,TEM-1,beta-lactamase,P62593,0.913449,NO,116,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.28,-3.376,2.096,4.78335,0.115,E,B,0.69,-0.12,0.343,,67.48,HPH,-1.39967,0.221079,0.00336175,0.913449 gb1_L231T,gb1_231,gb1,gb1,P06654,0.913453,NO,231,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.603,-3.339,1.736,,,,,,,0.219,,11.83,BHH,-1.82633,0.177985,0.00322797,0.913453 beta-lactamase_2500_V157G,beta-lactamase_2500_157,TEM-1,beta-lactamase_2500,P62593,0.913476,NO,157,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.751,-3.625,1.874,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.361275,0.00506849,0.913476 Pab1_K166M,Pab1_166,Pab1,Pab1,P04147,0.913543,NO,166,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.262,-4.373,3.111,,0.299,,l,,0,,,,PBO,-1.21033,0.175299,0.0011038,0.913543 WW_domain_G176F,WW_domain_176,Yap65,WW_domain,P46937,0.913547,NO,176,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.235,-4.126,2.891,6.33142,,,,,,2.71,,78.57,HOH,-1.35467,0.153962,0.00288552,0.913547 beta-lactamase_2500_P250Q,beta-lactamase_2500_250,TEM-1,beta-lactamase_2500,P62593,0.913558,NO,250,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.361275,0.00550899,0.913558 beta-lactamase_F13S,beta-lactamase_13,TEM-1,beta-lactamase,P62593,0.913589,NO,13,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-2.394,-2.56,0.166,,,,,,,4.079,,77.62,OHH,-2.382,0.221079,0.0029078,0.913589 beta-lactamase_0_G90S,beta-lactamase_0_90,TEM-1,beta-lactamase_0,P62593,0.913613,NO,90,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-2.091,-2.198,0.107,,0.598,T,A,0.29,0.32,2.04,,77.62,HOB,-1.52633,0.0500837,0.00490273,0.913613 beta-lactamase_156_E195Y,beta-lactamase_156_195,TEM-1,beta-lactamase_156,P62593,0.913687,NO,195,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.186,-4.374,2.188,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.111618,0.00496565,0.913687 beta-lactamase_V31A,beta-lactamase_31,TEM-1,beta-lactamase,P62593,0.91369,NO,31,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.822,-2.265,0.443,5.43781,,H,A,2.78,-0.46,2.885,,73.78,BHB,-2.03767,0.221079,0.00478065,0.91369 beta-lactamase_0_S51E,beta-lactamase_0_51,TEM-1,beta-lactamase_0,P62593,0.913691,NO,51,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.526,-3.428,1.902,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.0500837,0.00504821,0.913691 beta-lactamase_2500_E62T,beta-lactamase_2500_62,TEM-1,beta-lactamase_2500,P62593,0.913708,NO,62,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.193,-3.522,2.329,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.361275,0.00264802,0.913708 beta-lactamase_P165L,beta-lactamase_165,TEM-1,beta-lactamase,P62593,0.913723,NO,165,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.373,-3.388,2.015,5.33889,0.203,T,A,0.99,-0.31,0.414,,73.78,AOA,-1.359,0.221079,0.00549538,0.913723 kka2_1:8_A168S,kka2_1:8_168,Kka2,kka2_1:8,P00552,0.91373,NO,168,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.989,-2.65,0.661,,0.67,H,A,0.46,0.15,11.329,11.329,64.39,OHA,-2.12933,0.100394,0.00806773,0.91373 kka2_1:8_A168S,kka2_1:8_168,Kka2,kka2_1:8,P00552,0.91373,NO,168,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.989,-2.65,0.661,,0.67,H,A,0.46,0.15,11.329,11.329,64.39,OHA,-2.12933,0.100394,0.00806773,0.91373 beta-lactamase_625_L150G,beta-lactamase_625_150,TEM-1,beta-lactamase_625,P62593,0.913752,NO,150,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.326,-3.622,2.296,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.213352,0.00463171,0.913752 kka2_1:8_H106N,kka2_1:8_106,Kka2,kka2_1:8,P00552,0.913773,NO,106,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-3.13,-3.028,-0.102,,1.065,,a,0.87,-0.95,15.956,15.956,71.59,PBH,-2.10433,0.100394,0.00730778,0.913773 kka2_1:8_H106N,kka2_1:8_106,Kka2,kka2_1:8,P00552,0.913773,NO,106,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-3.13,-3.028,-0.102,,1.065,,a,0.87,-0.95,15.956,15.956,71.59,PBH,-2.10433,0.100394,0.00730778,0.913773 Pab1_N192M,Pab1_192,Pab1,Pab1,P04147,0.913837,NO,192,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-1.079,-4.522,3.443,,0.619,T,l,,2.28,,,,HPO,-1.231,0.175299,0.000273498,0.913837 kka2_1:1_V83F,kka2_1:1_83,Kka2,kka2_1:1,P00552,0.913851,NO,83,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-2.567,-2.568,0.001,,0.358,E,B,0.44,0.53,5.931,,71.59,AHH,-2.264,0.520039,0.00650486,0.913851 beta-lactamase_G216W,beta-lactamase_216,TEM-1,beta-lactamase,P62593,0.913914,NO,216,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.477,-5.45,3.973,4.91694,0.437,I,A,0.23,-0.58,1.718,,74.48,HOO,-1.68067,0.221079,0.00639568,0.913914 kka2_1:4_G30A,kka2_1:4_30,Kka2,kka2_1:4,P00552,0.913939,NO,30,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.596,-2.881,2.285,,0.54,S,g,0.29,3.76,,,,HOO,-1.51133,0.168804,0.00159208,0.913939 beta-lactamase_39_R239M,beta-lactamase_39_239,TEM-1,beta-lactamase_39,P62593,0.913942,NO,239,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.0495842,0.00213852,0.913942 beta-lactamase_156_S241F,beta-lactamase_156_241,TEM-1,beta-lactamase_156,P62593,0.913988,NO,241,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.111618,0.00452736,0.913988 gb1_T279Y,gb1_279,gb1,gb1,P06654,0.914003,NO,279,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.32,-3.933,2.613,,,,,,,0.529,,35.71,HPH,-1.50067,0.177985,0.00421454,0.914003 kka2_1:8_A237S,kka2_1:8_237,Kka2,kka2_1:8,P00552,0.914008,NO,237,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.12,-3.575,1.455,,0.068,H,A,0.46,-0.71,0.449,,92.05,HHA,-2.10433,0.100394,0.012257,0.914008 kka2_1:8_A237S,kka2_1:8_237,Kka2,kka2_1:8,P00552,0.914008,NO,237,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.12,-3.575,1.455,,0.068,H,A,0.46,-0.71,0.449,,92.05,HHA,-2.10433,0.100394,0.012257,0.914008 kka2_1:8_H106W,kka2_1:8_106,Kka2,kka2_1:8,P00552,0.914115,NO,106,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-3.13,-3.81,0.68,,1.065,,a,0.87,-0.95,15.956,15.956,71.59,PBH,-2.10433,0.100394,0.00730778,0.914115 kka2_1:8_H106W,kka2_1:8_106,Kka2,kka2_1:8,P00552,0.914115,NO,106,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-3.13,-3.81,0.68,,1.065,,a,0.87,-0.95,15.956,15.956,71.59,PBH,-2.10433,0.100394,0.00730778,0.914115 beta-lactamase_0_T198H,beta-lactamase_0_198,TEM-1,beta-lactamase_0,P62593,0.914122,NO,198,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.168,-3.211,1.043,,0.489,,B,0.22,-0.13,9.874,,73.78,HPH,-1.98767,0.0500837,0.004311,0.914122 Pab1_A141I,Pab1_141,Pab1,Pab1,P04147,0.914167,NO,141,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.461,-3.526,2.065,,0.34,H,A,0.52,-0.27,2.15,,79.03,BHH,-1.19433,0.175299,0.00165974,0.914167 PSD95pdz3_R318Q,PSD95pdz3_318,PSD95pdz3,PSD95pdz3,P31016,0.914227,NO,318,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.582,-3.131,1.549,4.94876,,,,,17.5609,,,,BBO,-1.40567,0.0758425,0.00110471,0.914227 beta-lactamase_39_R41W,beta-lactamase_39_41,TEM-1,beta-lactamase_39,P62593,0.914245,NO,41,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-0.942,-5.348,4.406,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.0495842,0.00123327,0.914245 gb1_T281L,gb1_281,gb1,gb1,P06654,0.914278,NO,281,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.828,-3.115,1.287,,,,,,,1.038,,35.71,HPA,-1.63667,0.177985,0.00284418,0.914278 beta-lactamase_L111K,beta-lactamase_111,TEM-1,beta-lactamase,P62593,0.914322,NO,111,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.76,-3.773,2.013,5.8705,0.328,T,A,0.84,0.93,3.836,,64.34,BHP,-1.884,0.221079,0.00480671,0.914322 beta-lactamase_R176F,beta-lactamase_176,TEM-1,beta-lactamase,P62593,0.914322,NO,176,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-0.863,-4.292,3.429,5.61264,0.385,T,B,0.68,-0.63,,,,ABA,-1.38867,0.221079,0.00105554,0.914322 kka2_1:8_L184A,kka2_1:8_184,Kka2,kka2_1:8,P00552,0.914328,NO,184,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.496,-2.814,1.318,,0.489,E,B,0.55,-0.06,4.495,,63.26,AHH,-1.24833,0.100394,0.00518742,0.914328 kka2_1:8_L184A,kka2_1:8_184,Kka2,kka2_1:8,P00552,0.914328,NO,184,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.496,-2.814,1.318,,0.489,E,B,0.55,-0.06,4.495,,63.26,AHH,-1.24833,0.100394,0.00518742,0.914328 beta-lactamase_39_W227C,beta-lactamase_39_227,TEM-1,beta-lactamase_39,P62593,0.914339,NO,227,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-0.982,-4.932,3.95,,0.272,,B,0.47,-0.29,1.37,,74.48,OHH,-1.595,0.0495842,0.00226019,0.914339 kka2_1:2_V84M,kka2_1:2_84,Kka2,kka2_1:2,P00552,0.914378,NO,84,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-2.279,-4.623,2.344,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.295029,0.00724019,0.914378 beta-lactamase_0_E238M,beta-lactamase_0_238,TEM-1,beta-lactamase_0,P62593,0.914406,NO,238,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.0500837,0.00743256,0.914406 hsp90_F583N,hsp90_583,hsp90,hsp90,P02829,0.914444,NO,583,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-3.22,-3.051,0,5.28185,1.112,S,l,1.1,0.87,,,,PHO,-3.003,0.368192,0.000222939,0.914444 beta-lactamase_156_N274I,beta-lactamase_156_274,TEM-1,beta-lactamase_156,P62593,0.91447,NO,274,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.111618,0.0110418,0.91447 beta-lactamase_0_I277E,beta-lactamase_0_277,TEM-1,beta-lactamase_0,P62593,0.914506,NO,277,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.869,-4.006,2.137,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.0500837,0.0169305,0.914506 beta-lactamase_0_T198A,beta-lactamase_0_198,TEM-1,beta-lactamase_0,P62593,0.914527,NO,198,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.168,-2.502,0.334,,0.489,,B,0.22,-0.13,9.874,,73.78,HPH,-1.98767,0.0500837,0.004311,0.914527 gb1_T244L,gb1_244,gb1,gb1,P06654,0.914552,NO,244,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.637,-2.694,1.057,,,,,,,0.202,,11.83,PPA,-1.92567,0.177985,0.00222755,0.914552 PSD95pdz3_N381Y,PSD95pdz3_381,PSD95pdz3,PSD95pdz3,P31016,0.914576,NO,381,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-1.41,-3.844,2.434,5.66057,,,,,28.2162,,,,BPH,-1.37767,0.0758425,0.000265374,0.914576 kka2_1:4_G21V,kka2_1:4_21,Kka2,kka2_1:4,P00552,0.91458,NO,21,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.368,-3.817,2.449,,0.586,T,l,0.75,-0.75,3.075,,71.59,HOH,-2.10167,0.168804,0.00709648,0.91458 Pab1_N139C,Pab1_139,Pab1,Pab1,P04147,0.914589,NO,139,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-1.079,-4.904,3.825,,0.062,H,A,,-0.73,,,,APB,-1.09667,0.175299,0.000339145,0.914589 PSD95pdz3_F340D,PSD95pdz3_340,PSD95pdz3,PSD95pdz3,P31016,0.914614,NO,340,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.524,-3.6,2.076,5.79283,,,,,11.8045,,,,PHH,-1.55767,0.0758425,0.000836987,0.914614 kka2_1:2_A137S,kka2_1:2_137,Kka2,kka2_1:2,P00552,0.914626,NO,137,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.156,-2.895,0.739,,0.029,H,A,0.46,0.34,1.323,,63.26,PHB,-2.559,0.295029,0.00515054,0.914626 beta-lactamase_0_Q276P,beta-lactamase_0_276,TEM-1,beta-lactamase_0,P62593,0.914665,NO,276,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.0500837,0.0191712,0.914665 beta-lactamase_2500_T264K,beta-lactamase_2500_264,TEM-1,beta-lactamase_2500,P62593,0.914695,NO,264,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.361275,0.0119399,0.914695 beta-lactamase_2500_T269I,beta-lactamase_2500_269,TEM-1,beta-lactamase_2500,P62593,0.914695,NO,269,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.361275,0.00950944,0.914695 beta-lactamase_0_K213P,beta-lactamase_0_213,TEM-1,beta-lactamase_0,P62593,0.914705,NO,213,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.81,-3.901,2.091,,0.67,,A,2.34,0.29,3.015,,67.83,ABH,-1.57767,0.0500837,0.00610411,0.914705 kka2_1:2_A176I,kka2_1:2_176,Kka2,kka2_1:2,P00552,0.914706,NO,176,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.621,-4.019,2.398,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.295029,0.0083587,0.914706 beta-lactamase_156_A235E,beta-lactamase_156_235,TEM-1,beta-lactamase_156,P62593,0.914729,NO,235,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.266,-3.558,2.292,,0.32,E,B,0.46,-0.86,1.344,,50,OHO,-0.89,0.111618,0.00493474,0.914729 beta-lactamase_0_P65C,beta-lactamase_0_65,TEM-1,beta-lactamase_0,P62593,0.91474,NO,65,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.894,-5.01,4.116,,0.098,E,B,0.52,-0.62,0.663,,40.56,HOH,-1.03233,0.0500837,0.00152776,0.91474 kka2_1:2_Q27P,kka2_1:2_27,Kka2,kka2_1:2,P00552,0.91475,NO,27,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-1.659,-3,1.341,,0.608,.,A,0.64,0.71,0.521,,65.53,PPP,-1.90733,0.295029,0.00595365,0.91475 beta-lactamase_2500_T126Q,beta-lactamase_2500_126,TEM-1,beta-lactamase_2500,P62593,0.914771,NO,126,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.122,-3.945,2.823,,0.05,H,A,0.22,-0.05,0.817,,44.41,HPH,-1.60467,0.361275,0.00244552,0.914771 beta-lactamase_0_N130G,beta-lactamase_0_130,TEM-1,beta-lactamase_0,P62593,0.914779,NO,130,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-0.798,-2.908,2.11,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.0500837,0.000683376,0.914779 Pab1_Y197V,Pab1_197,Pab1,Pab1,P04147,0.914804,NO,197,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-1.345,-3.217,1.872,,,,,,,0.891,,80.42,HHH,-1.41767,0.175299,0.00302474,0.914804 kka2_1:2_A14Y,kka2_1:2_14,Kka2,kka2_1:2,P00552,0.914812,NO,14,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.837,-4.418,2.581,,0.728,G,A,0.46,0.7,0.36,,71.59,HHH,-1.82567,0.295029,0.00706614,0.914812 beta-lactamase_0_P65S,beta-lactamase_0_65,TEM-1,beta-lactamase_0,P62593,0.914955,NO,65,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.894,-3.44,2.546,,0.098,E,B,0.52,-0.62,0.663,,40.56,HOH,-1.03233,0.0500837,0.00152776,0.914955 kka2_1:8_P194G,kka2_1:8_194,Kka2,kka2_1:8,P00552,0.914967,NO,194,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.846,-3.359,2.513,,0.308,G,A,0.52,-1.19,4.861,,53.03,HOP,-0.888333,0.100394,0.00314194,0.914967 kka2_1:8_P194G,kka2_1:8_194,Kka2,kka2_1:8,P00552,0.914967,NO,194,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.846,-3.359,2.513,,0.308,G,A,0.52,-1.19,4.861,,53.03,HOP,-0.888333,0.100394,0.00314194,0.914967 beta-lactamase_0_M66H,beta-lactamase_0_66,TEM-1,beta-lactamase_0,P62593,0.914984,NO,66,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.362,-4.866,3.504,,0.013,,A,0.55,-0.7,1.204,,73.08,OHH,-1.49567,0.0500837,0.00412876,0.914984 kka2_1:2_V36G,kka2_1:2_36,Kka2,kka2_1:2,P00552,0.914985,NO,36,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-0.898,-3.694,2.796,,0.292,E,B,1.48,0.21,1.064,,52.27,HHH,-1.484,0.295029,0.00245633,0.914985 beta-lactamase_0_Q88H,beta-lactamase_0_88,TEM-1,beta-lactamase_0,P62593,0.914994,NO,88,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.086,-4.599,2.513,,0.807,,B,0.64,2.03,0.4,,77.62,APH,-1.53433,0.0500837,0.00504167,0.914994 PSD95pdz3_F325V,PSD95pdz3_325,PSD95pdz3,PSD95pdz3,P31016,0.915019,NO,325,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.524,-2.985,1.461,5.50654,,,,,12.7236,,,,OHP,-1.314,0.0758425,0.00102273,0.915019 beta-lactamase_39_L74N,beta-lactamase_39_74,TEM-1,beta-lactamase_39,P62593,0.91502,NO,74,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.296,-4.114,2.818,,,H,A,0.55,-0.91,1.581,,50,HHO,-1.34933,0.0495842,0.00493255,0.91502 kka2_1:8_P179E,kka2_1:8_179,Kka2,kka2_1:8,P00552,0.915031,NO,179,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.974,-3.589,2.615,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.100394,0.00298346,0.915031 kka2_1:8_P179E,kka2_1:8_179,Kka2,kka2_1:8,P00552,0.915031,NO,179,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.974,-3.589,2.615,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.100394,0.00298346,0.915031 beta-lactamase_0_L197G,beta-lactamase_0_197,TEM-1,beta-lactamase_0,P62593,0.915066,NO,197,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.853,-3.681,2.828,,0.007,S,B,0.55,0.33,1.087,,60.14,HHP,-1.833,0.0500837,0.00144602,0.915066 beta-lactamase_2500_A211C,beta-lactamase_2500_211,TEM-1,beta-lactamase_2500,P62593,0.915078,NO,211,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.896,-5.066,3.17,,0.369,T,A,0.46,-0.69,2.061,,77.62,AHA,-1.94633,0.361275,0.00648183,0.915078 kka2_1:4_R18M,kka2_1:4_18,Kka2,kka2_1:4,P00552,0.915086,NO,18,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.055,-3.102,1.047,,0.474,T,A,1.2,0.54,8.405,8.405,71.59,ABH,-1.821,0.168804,0.00724065,0.915086 beta-lactamase_39_V42F,beta-lactamase_39_42,TEM-1,beta-lactamase_39,P62593,0.915102,NO,42,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.564,-3.895,2.331,,0.017,E,B,0.44,-0.51,1.86,,63.99,BHO,-1.042,0.0495842,0.00404515,0.915102 beta-lactamase_2500_K286F,beta-lactamase_2500_286,TEM-1,beta-lactamase_2500,P62593,0.915105,NO,286,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.361275,,0.915105 PSD95pdz3_L342N,PSD95pdz3_342,PSD95pdz3,PSD95pdz3,P31016,0.915193,NO,342,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.347,-3.805,2.458,5.03015,,,,,12.0762,,,,HHH,-1.428,0.0758425,0.00081112,0.915193 beta-lactamase_0_G226L,beta-lactamase_0_226,TEM-1,beta-lactamase_0,P62593,0.915196,NO,226,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.461,-3.765,2.304,,0.701,T,l,0.29,-0.25,23.034,23.034,74.48,HOH,-1.42933,0.0500837,0.00665294,0.915196 beta-lactamase_0_L205R,beta-lactamase_0_205,TEM-1,beta-lactamase_0,P62593,0.915226,NO,205,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.922,-3.987,3.065,,,H,A,0.55,-0.46,1.065,,42.31,PHH,-1.57767,0.0500837,0.00255802,0.915226 PSD95pdz3_I336M,PSD95pdz3_336,PSD95pdz3,PSD95pdz3,P31016,0.915249,NO,336,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.63,-3.712,2.082,5.11321,,,,,13.6363,,,,OHH,-1.38733,0.0758425,0.000887923,0.915249 beta-lactamase_2500_R41T,beta-lactamase_2500_41,TEM-1,beta-lactamase_2500,P62593,0.915272,NO,41,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-0.942,-3.385,2.443,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.361275,0.00123327,0.915272 beta-lactamase_S240E,beta-lactamase_240,TEM-1,beta-lactamase,P62593,0.915286,NO,240,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.537,-3.464,1.927,4.75024,,,B,0.74,-0.74,0.357,,65.38,OPB,-1.263,0.221079,0.00591201,0.915286 beta-lactamase_0_T116F,beta-lactamase_0_116,TEM-1,beta-lactamase_0,P62593,0.915314,NO,116,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.28,-4.243,2.963,,0.115,E,B,0.22,-0.12,1.356,,67.48,HPH,-1.39967,0.0500837,0.00336175,0.915314 beta-lactamase_2500_E119A,beta-lactamase_2500_119,TEM-1,beta-lactamase_2500,P62593,0.915317,NO,119,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.412,-2.242,0.83,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.361275,0.00386966,0.915317 Pab1_A179Y,Pab1_179,Pab1,Pab1,P04147,0.915333,NO,179,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.013,-3.98,2.967,,0.078,H,A,0.61,0.5,,,,HHB,-1.51233,0.175299,0.000291703,0.915333 kka2_1:8_A78S,kka2_1:8_78,Kka2,kka2_1:8,P00552,0.91535,NO,78,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.744,-3.309,1.565,,0.078,,B,1.04,-0.53,1.251,,56.06,OHH,-1.863,0.100394,0.00457299,0.91535 kka2_1:8_A78S,kka2_1:8_78,Kka2,kka2_1:8,P00552,0.91535,NO,78,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.744,-3.309,1.565,,0.078,,B,1.04,-0.53,1.251,,56.06,OHH,-1.863,0.100394,0.00457299,0.91535 kka2_1:1_A35S,kka2_1:1_35,Kka2,kka2_1:1,P00552,0.915367,NO,35,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.127,-2.197,0.07,,0.107,E,B,0.46,1.05,8.405,8.405,71.59,HHH,-1.31767,0.520039,0.00630016,0.915367 beta-lactamase_L47C,beta-lactamase_47,TEM-1,beta-lactamase,P62593,0.915375,NO,47,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.876,-5.002,3.126,5.27297,0.007,E,B,1.07,0.2,1.244,,67.83,AHA,-1.639,0.221079,0.00439844,0.915375 beta-lactamase_P25N,beta-lactamase_25,TEM-1,beta-lactamase,P62593,0.915375,NO,25,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.526,-3.702,2.176,5.6134,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.221079,0.00347571,0.915375 beta-lactamase_H285G,beta-lactamase_285,TEM-1,beta-lactamase,P62593,0.915418,NO,285,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-1.845,-3.36,1.515,5.64289,0.312,T,a,0.35,0.64,1.401,,72.73,BBH,-1.64567,0.221079,0.101555,0.915418 beta-lactamase_156_I125S,beta-lactamase_156_125,TEM-1,beta-lactamase_156,P62593,0.915441,NO,125,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.441,-2.843,1.402,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.111618,0.00383964,0.915441 beta-lactamase_0_L28W,beta-lactamase_0_28,TEM-1,beta-lactamase_0,P62593,0.915448,NO,28,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.579,-5.332,3.753,,0.277,H,A,0.55,-0.16,9.35,9.35,93.01,PHH,-2.11333,0.0500837,0.00359321,0.915448 beta-lactamase_0_L74W,beta-lactamase_0_74,TEM-1,beta-lactamase_0,P62593,0.915454,NO,74,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.296,-5.261,3.965,,,H,A,0.55,-0.91,1.46,,50,HHO,-1.34933,0.0500837,0.00493255,0.915454 Pab1_A158R,Pab1_158,Pab1,Pab1,P04147,0.915471,NO,158,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.154,-3.671,2.517,,,,,,,1.197,,56.33,HHP,-1.40733,0.175299,0.000649733,0.915471 beta-lactamase_F228A,beta-lactamase_228,TEM-1,beta-lactamase,P62593,0.915514,NO,228,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-2.342,-2.562,0.22,5.33448,0.154,E,B,1.1,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.221079,0.0046669,0.915514 Pab1_T145G,Pab1_145,Pab1,Pab1,P04147,0.915524,NO,145,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.067,-3.175,2.108,,0.237,H,A,0.3,0.69,,,,APH,-1.135,0.175299,0.000331088,0.915524 beta-lactamase_0_T264P,beta-lactamase_0_264,TEM-1,beta-lactamase_0,P62593,0.915528,NO,264,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.0500837,0.0119399,0.915528 beta-lactamase_0_I171T,beta-lactamase_0_171,TEM-1,beta-lactamase_0,P62593,0.915581,NO,171,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-2.431,-2.05,-0.381,,0.361,,B,0.48,0.53,16.954,16.954,77.62,HHO,-1.55533,0.0500837,0.00623355,0.915581 beta-lactamase_R63L,beta-lactamase_63,TEM-1,beta-lactamase,P62593,0.915597,NO,63,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-0.943,-2.476,1.533,5.49979,0.218,,B,0.45,-0.31,0.677,,44.06,ABH,-0.992333,0.221079,0.00126938,0.915597 PSD95pdz3_R368M,PSD95pdz3_368,PSD95pdz3,PSD95pdz3,P31016,0.915598,NO,368,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.582,-4.162,2.58,6.13355,,,,,18.1818,,,,HBP,-1.50033,0.0758425,0.000451517,0.915598 kka2_1:8_R145G,kka2_1:8_145,Kka2,kka2_1:8,P00552,0.915605,NO,145,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.804,-2.912,1.108,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.100394,0.00846663,0.915605 kka2_1:8_R145G,kka2_1:8_145,Kka2,kka2_1:8,P00552,0.915605,NO,145,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.804,-2.912,1.108,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.100394,0.00846663,0.915605 beta-lactamase_R63Q,beta-lactamase_63,TEM-1,beta-lactamase,P62593,0.915639,NO,63,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-0.943,-3.532,2.589,5.49979,0.218,,B,0.45,-0.31,0.677,,44.06,ABH,-0.992333,0.221079,0.00126938,0.915639 beta-lactamase_M127S,beta-lactamase_127,TEM-1,beta-lactamase,P62593,0.915663,NO,127,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-2.251,-3.644,1.393,5.40552,0.312,S,A,1.07,0.32,1.671,,72.73,PHP,-1.40433,0.221079,0.00437927,0.915663 kka2_1:4_E86R,kka2_1:4_86,Kka2,kka2_1:4,P00552,0.915663,NO,86,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.86,-3.888,2.028,,0.369,.,B,1.04,1.92,4.451,,63.26,PAH,-1.98067,0.168804,0.00642858,0.915663 beta-lactamase_2500_V106T,beta-lactamase_2500_106,TEM-1,beta-lactamase_2500,P62593,0.915692,NO,106,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.218,-3.428,2.21,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.361275,0.00304168,0.915692 beta-lactamase_625_G52L,beta-lactamase_625_52,TEM-1,beta-lactamase_625,P62593,0.915801,NO,52,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.149,-3.755,2.606,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.213352,0.00340138,0.915801 beta-lactamase_156_M184T,beta-lactamase_156_184,TEM-1,beta-lactamase_156,P62593,0.915807,NO,184,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.593,-2.764,1.171,,,H,A,0.55,-0.87,1.671,,62.94,HHH,-1.41,0.111618,0.00356019,0.915807 beta-lactamase_625_A215K,beta-lactamase_625_215,TEM-1,beta-lactamase_625,P62593,0.915829,NO,215,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.503,-3.575,2.072,,,,a,0.46,-0.93,3.583,,74.48,HHO,-1.42633,0.213352,0.00544007,0.915829 beta-lactamase_2500_M184V,beta-lactamase_2500_184,TEM-1,beta-lactamase_2500,P62593,0.91584,NO,184,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.593,-2.346,0.753,,,H,A,0.55,-0.87,2.893,,62.94,HHH,-1.41,0.361275,0.00356019,0.91584 beta-lactamase_V82H,beta-lactamase_82,TEM-1,beta-lactamase,P62593,0.915896,NO,82,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.325,-4.872,3.547,5.27777,0.267,H,A,0.96,0.08,1.379,,93.01,BHA,-1.28567,0.221079,0.00397046,0.915896 beta-lactamase_0_P25G,beta-lactamase_0_25,TEM-1,beta-lactamase_0,P62593,0.915918,NO,25,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.526,-2.198,0.672,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.0500837,0.00347571,0.915918 kka2_1:8_E149G,kka2_1:8_149,Kka2,kka2_1:8,P00552,0.915924,NO,149,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.994,-3.566,1.572,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.100394,0.00803343,0.915924 kka2_1:8_E149G,kka2_1:8_149,Kka2,kka2_1:8,P00552,0.915924,NO,149,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.994,-3.566,1.572,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.100394,0.00803343,0.915924 beta-lactamase_39_Q203I,beta-lactamase_39_203,TEM-1,beta-lactamase_39,P62593,0.915957,NO,203,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.168,-3.973,1.805,,0.47,H,A,0.64,-0.38,1.453,,65.38,BPP,-1.614,0.0495842,0.00631514,0.915957 beta-lactamase_2500_Y44M,beta-lactamase_2500_44,TEM-1,beta-lactamase_2500,P62593,0.915966,NO,44,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-2.547,-2.521,-0.026,,,E,B,0.21,-0.45,2.184,,73.78,OHH,-1.86267,0.361275,0.00426364,0.915966 beta-lactamase_F70C,beta-lactamase_70,TEM-1,beta-lactamase,P62593,0.915988,NO,70,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.169,-4.871,3.702,5.42055,,H,A,1.1,-1.34,1.14,,63.99,PHB,-0.980667,0.221079,0.00193499,0.915988 beta-lactamase_L73T,beta-lactamase_73,TEM-1,beta-lactamase,P62593,0.915988,NO,73,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.507,-3.582,2.075,5.84139,,H,A,1.75,-0.64,2.09,,67.83,HHH,-1.487,0.221079,0.00488983,0.915988 beta-lactamase_W163Q,beta-lactamase_163,TEM-1,beta-lactamase,P62593,0.915988,NO,163,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-1.843,-2.929,1.086,6.2765,0.467,,B,1.22,-0.5,3.642,,63.99,BHA,-1.269,0.221079,0.00418955,0.915988 kka2_1:2_P167Q,kka2_1:2_167,Kka2,kka2_1:2,P00552,0.915997,NO,167,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-2.403,-4.147,1.744,,0.18,H,A,0.52,0.75,3.6,,64.39,HOH,-2.26633,0.295029,0.00543203,0.915997 E1_Ubiquitin_G47L,E1_Ubiquitin_47,Uba1,E1_Ubiquitin,P0CG63,0.916004,NO,47,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.999,-3.549,2.55,,0.057,T,l,,-1.21,,,,HOB,-1.195,0.18783,0.00142261,0.916004 beta-lactamase_2500_H94G,beta-lactamase_2500_94,TEM-1,beta-lactamase_2500,P62593,0.916012,NO,94,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-2.5,-3.593,1.093,,0.776,,B,0.17,1.24,1.176,,77.62,HBH,-1.872,0.361275,0.00389226,0.916012 beta-lactamase_2500_P60N,beta-lactamase_2500_60,TEM-1,beta-lactamase_2500,P62593,0.916083,NO,60,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-2.469,-3.804,1.335,,0.256,T,A,0.52,-0.56,1.581,,77.62,BOA,-1.97633,0.361275,0.00521318,0.916083 beta-lactamase_M268H,beta-lactamase_268,TEM-1,beta-lactamase,P62593,0.916086,NO,268,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-2.023,-4.758,2.735,5.4797,0.471,H,A,0.09,0.3,1.071,,65.73,PHA,-2.16233,0.221079,0.0102525,0.916086 kka2_1:2_T187C,kka2_1:2_187,Kka2,kka2_1:2,P00552,0.916099,NO,187,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.273,-2.642,1.369,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.295029,0.00693073,0.916099 beta-lactamase_0_N98L,beta-lactamase_0_98,TEM-1,beta-lactamase_0,P62593,0.916109,NO,98,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-2.973,-3.59,0.617,,0.963,G,A,0.61,1.35,14.853,14.853,77.62,PPA,-2.07867,0.0500837,0.00505389,0.916109 kka2_1:8_L67R,kka2_1:8_67,Kka2,kka2_1:8,P00552,0.916136,NO,67,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.741,-3.961,3.22,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.100394,0.00102787,0.916136 kka2_1:8_L67R,kka2_1:8_67,Kka2,kka2_1:8,P00552,0.916136,NO,67,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.741,-3.961,3.22,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.100394,0.00102787,0.916136 beta-lactamase_0_N50P,beta-lactamase_0_50,TEM-1,beta-lactamase_0,P62593,0.916144,NO,50,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-2.979,-3.95,0.971,,0.912,T,A,0.61,1.24,9.874,9.874,77.62,HPP,-2.134,0.0500837,0.0047211,0.916144 beta-lactamase_0_E210I,beta-lactamase_0_210,TEM-1,beta-lactamase_0,P62593,0.916152,NO,210,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.319,-2.456,0.137,,0.476,H,A,1.04,0.75,3.618,,77.62,HAH,-1.88567,0.0500837,0.00663582,0.916152 gb1_G264S,gb1_264,gb1,gb1,P06654,0.916185,NO,264,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.833,-3.122,1.289,,,,,,,0.864,,44.87,POH,-1.61267,0.177985,0.0049716,0.916185 beta-lactamase_0_S104V,beta-lactamase_0_104,TEM-1,beta-lactamase_0,P62593,0.916188,NO,104,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.015,-3.487,2.472,,0.04,,b,0.27,0.57,1.148,,63.29,HPO,-1.05267,0.0500837,0.00218083,0.916188 beta-lactamase_0_V259C,beta-lactamase_0_259,TEM-1,beta-lactamase_0,P62593,0.916207,NO,259,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.0500837,0.0070773,0.916207 kka2_1:8_L57P,kka2_1:8_57,Kka2,kka2_1:8,P00552,0.916208,NO,57,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.898,-3.173,1.275,,0.343,T,A,0.55,0.98,13.359,13.359,52.65,HHP,-2.20733,0.100394,0.00723769,0.916208 kka2_1:8_L57P,kka2_1:8_57,Kka2,kka2_1:8,P00552,0.916208,NO,57,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.898,-3.173,1.275,,0.343,T,A,0.55,0.98,13.359,13.359,52.65,HHP,-2.20733,0.100394,0.00723769,0.916208 PSD95pdz3_R318A,PSD95pdz3_318,PSD95pdz3,PSD95pdz3,P31016,0.916271,NO,318,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.582,-2.759,1.177,4.94876,,,,,17.5609,,,,BBO,-1.40567,0.0758425,0.00110471,0.916271 kka2_1:4_G164A,kka2_1:4_164,Kka2,kka2_1:4,P00552,0.916285,NO,164,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.869,-3.006,2.137,,0.862,T,l,0.75,1.45,1.539,,64.39,POH,-1.828,0.168804,0.00442091,0.916285 kka2_1:2_L60D,kka2_1:2_60,Kka2,kka2_1:2,P00552,0.916324,NO,60,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.997,-4.183,3.186,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.295029,0.00262176,0.916324 beta-lactamase_0_T187V,beta-lactamase_0_187,TEM-1,beta-lactamase_0,P62593,0.916352,NO,187,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.401,-3.287,1.886,,0.007,H,A,0.22,-1.19,3.259,,67.48,PPH,-1.69633,0.0500837,0.00491782,0.916352 beta-lactamase_R7Y,beta-lactamase_7,TEM-1,beta-lactamase,P62593,0.916358,NO,7,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.683,-2.623,0.94,,,,,,,2.44,,67.13,HBH,-1.96267,0.221079,0.00211375,0.916358 beta-lactamase_0_V82H,beta-lactamase_0_82,TEM-1,beta-lactamase_0,P62593,0.916363,NO,82,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.325,-4.872,3.547,,0.267,H,A,0.44,0.08,1.893,,93.01,BHA,-1.28567,0.0500837,0.00397046,0.916363 PSD95pdz3_S339F,PSD95pdz3_339,PSD95pdz3,PSD95pdz3,P31016,0.916377,NO,339,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.519,-3.749,2.23,5.34493,,,,,12.2167,,,,HPH,-1.55767,0.0758425,0.00084982,0.916377 beta-lactamase_0_A133L,beta-lactamase_0_133,TEM-1,beta-lactamase_0,P62593,0.916402,NO,133,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.186,-3.396,2.21,,,H,A,0.46,-0.86,2.148,,67.83,HHP,-0.988333,0.0500837,0.00468022,0.916402 beta-lactamase_0_A211T,beta-lactamase_0_211,TEM-1,beta-lactamase_0,P62593,0.916417,NO,211,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.896,-2.901,1.005,,0.369,T,A,0.46,-0.69,8.527,8.527,77.62,AHA,-1.94633,0.0500837,0.00648183,0.916417 beta-lactamase_2500_K32G,beta-lactamase_2500_32,TEM-1,beta-lactamase_2500,P62593,0.916428,NO,32,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.984,-3.506,1.522,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.361275,0.00401283,0.916428 gb1_A246H,gb1_246,gb1,gb1,P06654,0.916456,NO,246,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.175,-4.416,3.241,,,,,,,,,,AHH,-1.87033,0.177985,0.00190625,0.916456 beta-lactamase_2500_R41M,beta-lactamase_2500_41,TEM-1,beta-lactamase_2500,P62593,0.916471,NO,41,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-0.942,-4.506,3.564,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.361275,0.00123327,0.916471 beta-lactamase_0_T198N,beta-lactamase_0_198,TEM-1,beta-lactamase_0,P62593,0.916483,NO,198,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.168,-3.569,1.401,,0.489,,B,0.22,-0.13,9.874,,73.78,HPH,-1.98767,0.0500837,0.004311,0.916483 kka2_1:8_E149A,kka2_1:8_149,Kka2,kka2_1:8,P00552,0.9165,NO,149,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.994,-2.44,0.446,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.100394,0.00803343,0.9165 kka2_1:8_E149A,kka2_1:8_149,Kka2,kka2_1:8,P00552,0.9165,NO,149,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.994,-2.44,0.446,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.100394,0.00803343,0.9165 Pab1_G126A,Pab1_126,Pab1,Pab1,P04147,0.916505,NO,126,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.985,-1.923,0.938,,0.011,T,A,0.46,-0.07,2.349,,80.42,OOP,-1.032,0.175299,0.00109814,0.916505 beta-lactamase_0_A183C,beta-lactamase_0_183,TEM-1,beta-lactamase_0,P62593,0.916512,NO,183,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.231,-4.684,3.453,,0.155,H,A,0.46,-0.91,1.48,,77.62,HHH,-1.53367,0.0500837,0.00296631,0.916512 kka2_1:2_F37L,kka2_1:2_37,Kka2,kka2_1:2,P00552,0.916513,NO,37,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.427,-2.514,1.087,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.295029,0.00586193,0.916513 beta-lactamase_0_L197A,beta-lactamase_0_197,TEM-1,beta-lactamase_0,P62593,0.916522,NO,197,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.853,-2.357,1.504,,0.007,S,B,0.55,0.33,1.087,,60.14,HHP,-1.833,0.0500837,0.00144602,0.916522 kka2_1:2_A87E,kka2_1:2_87,Kka2,kka2_1:2,P00552,0.91664,NO,87,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.917,-2.476,0.559,,1.039,S,L,0.46,1.57,22.675,22.675,65.53,AHO,-1.822,0.295029,0.00791281,0.91664 kka2_1:2_S105G,kka2_1:2_105,Kka2,kka2_1:2,P00552,0.91664,NO,105,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.945,-2.84,0.895,,0.056,S,B,0.27,-1.04,3.442,,65.53,PPB,-2.17033,0.295029,0.00847233,0.91664 beta-lactamase_0_T193E,beta-lactamase_0_193,TEM-1,beta-lactamase_0,P62593,0.916663,NO,193,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.914,-3.756,1.842,,0.439,H,a,0.22,0.33,11.546,11.546,63.99,HPO,-1.52133,0.0500837,0.00482669,0.916663 beta-lactamase_0_A230Q,beta-lactamase_0_230,TEM-1,beta-lactamase_0,P62593,0.91667,NO,230,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.154,-4.025,2.871,,0.01,E,B,0.46,-1.17,2.179,,50,HHA,-1.079,0.0500837,0.00516841,0.91667 beta-lactamase_0_N50R,beta-lactamase_0_50,TEM-1,beta-lactamase_0,P62593,0.916671,NO,50,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-2.979,-3.883,0.904,,0.912,T,A,0.61,1.24,9.874,9.874,77.62,HPP,-2.134,0.0500837,0.0047211,0.916671 beta-lactamase_A200F,beta-lactamase_200,TEM-1,beta-lactamase,P62593,0.916671,NO,200,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.878,-4.397,2.519,5.19406,0.757,H,A,0.47,-0.19,0.436,,77.62,HHP,-2.001,0.221079,0.0060056,0.916671 beta-lactamase_E62A,beta-lactamase_62,TEM-1,beta-lactamase,P62593,0.916671,NO,62,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.193,-2.533,1.34,5.93066,0.342,S,B,1.52,-0.3,3.139,,73.08,AAB,-1.417,0.221079,0.00264802,0.916671 beta-lactamase_P25Y,beta-lactamase_25,TEM-1,beta-lactamase,P62593,0.916671,NO,25,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.526,-4.327,2.801,5.6134,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.221079,0.00347571,0.916671 beta-lactamase_2500_P217V,beta-lactamase_2500_217,TEM-1,beta-lactamase_2500,P62593,0.916686,NO,217,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-2.062,-3.65,1.588,,0.496,I,A,0.52,-0.33,0.431,,74.48,OOH,-1.64333,0.361275,0.00463211,0.916686 WW_domain_T196S,WW_domain_196,Yap65,WW_domain,P46937,0.916714,NO,196,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.782,-2.386,0.604,5.5744,,,,,,5.836,,70.04,PPP,-1.732,0.153962,0.00421377,0.916714 WW_domain_A175D,WW_domain_175,Yap65,WW_domain,P46937,0.916719,NO,175,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.631,-2.205,0.574,6.69537,,,,,,6.257,,83.93,OHO,-1.30033,0.153962,0.00326874,0.916719 gb1_N263S,gb1_263,gb1,gb1,P06654,0.916726,NO,263,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-1.162,-2.713,1.551,,,,,,,,,,APO,-2.04233,0.177985,0.0035297,0.916726 beta-lactamase_156_G114V,beta-lactamase_156_114,TEM-1,beta-lactamase_156,P62593,0.916747,NO,114,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.094,-3.65,2.556,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.111618,0.00224919,0.916747 PSD95pdz3_D348N,PSD95pdz3_348,PSD95pdz3,PSD95pdz3,P31016,0.916751,NO,348,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.264,-2.905,1.641,5.02473,,,,,16.8925,,,,HAH,-1.306,0.0758425,0.000731866,0.916751 beta-lactamase_0_P143K,beta-lactamase_0_143,TEM-1,beta-lactamase_0,P62593,0.916755,NO,143,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.967,-3.581,2.614,,0.075,H,A,0.52,-0.37,11.868,11.868,66.78,OOB,-1.354,0.0500837,0.00114551,0.916755 beta-lactamase_156_V72G,beta-lactamase_156_72,TEM-1,beta-lactamase_156,P62593,0.916794,NO,72,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.658,-3.477,1.819,,,H,A,0.44,-1.03,1.92,,65.73,BHH,-1.32167,0.111618,0.00501194,0.916794 beta-lactamase_0_S80M,beta-lactamase_0_80,TEM-1,beta-lactamase_0,P62593,0.916846,NO,80,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.029,-4.671,2.642,,0.192,H,A,0.27,0.46,12.403,12.403,77.62,HPB,-1.44567,0.0500837,0.00565569,0.916846 beta-lactamase_2500_E175G,beta-lactamase_2500_175,TEM-1,beta-lactamase_2500,P62593,0.91685,NO,175,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.336,-3.483,1.147,,0.551,,A,1.04,1.05,5.316,,77.62,AAB,-1.31233,0.361275,0.00482205,0.91685 beta-lactamase_156_S233C,beta-lactamase_156_233,TEM-1,beta-lactamase_156,P62593,0.916872,NO,233,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.886,-4.789,2.903,,0.016,E,B,0.27,-1.01,4.111,,77.62,BPO,-1.17267,0.111618,0.00311415,0.916872 WW_domain_D201K,WW_domain_201,Yap65,WW_domain,P46937,0.916876,NO,201,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.369,-3.226,1.857,4.90312,,,,,,20.806,20.806,70.04,PAO,-1.456,0.153962,0.00248402,0.916876 beta-lactamase_R176S,beta-lactamase_176,TEM-1,beta-lactamase,P62593,0.916881,NO,176,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-0.863,-3.386,2.523,5.61264,0.385,T,B,0.68,-0.63,,,,ABA,-1.38867,0.221079,0.00105554,0.916881 beta-lactamase_0_V101Y,beta-lactamase_0_101,TEM-1,beta-lactamase_0,P62593,0.916886,NO,101,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.295,-4.116,2.821,,0.342,,B,0.44,0,1.61,,73.08,HHA,-1.54367,0.0500837,0.00374492,0.916886 beta-lactamase_2500_W163K,beta-lactamase_2500_163,TEM-1,beta-lactamase_2500,P62593,0.916915,NO,163,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-1.843,-2.971,1.128,,0.467,,B,0.47,-0.5,32.624,32.624,63.99,BHA,-1.269,0.361275,0.00418955,0.916915 kka2_1:2_F133Y,kka2_1:2_133,Kka2,kka2_1:2,P00552,0.916923,NO,133,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-0.871,-2.422,1.551,,0.178,.,B,0.58,0.43,1.999,,42.42,OHA,-0.871667,0.295029,0.00182168,0.916923 beta-lactamase_L282A,beta-lactamase_282,TEM-1,beta-lactamase,P62593,0.91694,NO,282,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.586,-3.183,1.597,5.16743,0.007,H,A,1.07,0.34,31.31,31.31,63.99,PHH,-1.82367,0.221079,0.0449821,0.91694 kka2_1:2_T125P,kka2_1:2_125,Kka2,kka2_1:2,P00552,0.916945,NO,125,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.622,-3.993,1.371,,0.791,T,A,0.22,0.33,2.029,,92.05,BPH,-1.56933,0.295029,0.00821755,0.916945 beta-lactamase_0_E164Q,beta-lactamase_0_164,TEM-1,beta-lactamase_0,P62593,0.916956,NO,164,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-0.948,-3.358,2.41,,0.011,T,B,1.04,-0.4,1.011,,64.69,HAO,-1.388,0.0500837,0.00137286,0.916956 kka2_1:8_K138C,kka2_1:8_138,Kka2,kka2_1:8,P00552,0.916962,NO,138,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-2.5,-5.226,2.726,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.100394,0.00628542,0.916962 kka2_1:8_K138C,kka2_1:8_138,Kka2,kka2_1:8,P00552,0.916962,NO,138,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-2.5,-5.226,2.726,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.100394,0.00628542,0.916962 beta-lactamase_0_G234V,beta-lactamase_0_234,TEM-1,beta-lactamase_0,P62593,0.916982,NO,234,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.62,-3.754,3.134,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.0500837,0.000889577,0.916982 gb1_T281H,gb1_281,gb1,gb1,P06654,0.916996,NO,281,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.828,-4.401,2.573,,,,,,,1.038,,35.71,HPA,-1.63667,0.177985,0.00284418,0.916996 beta-lactamase_2500_T27I,beta-lactamase_2500_27,TEM-1,beta-lactamase_2500,P62593,0.917001,NO,27,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.905,-3.752,1.847,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.361275,0.00306559,0.917001 beta-lactamase_2500_R41Q,beta-lactamase_2500_41,TEM-1,beta-lactamase_2500,P62593,0.917037,NO,41,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-0.942,-3.498,2.556,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.361275,0.00123327,0.917037 kka2_1:2_F240V,kka2_1:2_240,Kka2,kka2_1:2,P00552,0.917037,NO,240,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-0.911,-3.287,2.376,,,H,A,0.58,-1.21,0.373,,50.38,BHH,-1.67267,0.295029,0.00552543,0.917037 beta-lactamase_0_M66Q,beta-lactamase_0_66,TEM-1,beta-lactamase_0,P62593,0.917056,NO,66,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.362,-3.949,2.587,,0.013,,A,0.55,-0.7,1.204,,73.08,OHH,-1.49567,0.0500837,0.00412876,0.917056 beta-lactamase_0_L150A,beta-lactamase_0_150,TEM-1,beta-lactamase_0,P62593,0.917059,NO,150,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.326,-2.051,0.725,,,H,A,0.55,-0.2,2.128,,62.94,HHB,-1.86167,0.0500837,0.00463171,0.917059 beta-lactamase_0_D113K,beta-lactamase_0_113,TEM-1,beta-lactamase_0,P62593,0.91706,NO,113,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.829,-2.696,0.867,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.0500837,0.00474112,0.91706 kka2_1:4_C31E,kka2_1:4_31,Kka2,kka2_1:4,P00552,0.917071,NO,31,C,E,CE,Special,negativeCharge,5.07,3.22,-1.85,170,121,147,26,108.5,138.4,29.9,-2.246,-1.966,-0.28,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.168804,0.00681582,0.917071 beta-lactamase_T187A,beta-lactamase_187,TEM-1,beta-lactamase,P62593,0.917076,NO,187,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.401,-3.072,1.671,5.11453,0.007,H,A,0.3,-1.19,1.751,,67.48,PPH,-1.69633,0.221079,0.00491782,0.917076 beta-lactamase_0_E175A,beta-lactamase_0_175,TEM-1,beta-lactamase_0,P62593,0.917098,NO,175,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.336,-2.1,-0.236,,0.551,,A,1.04,1.05,2.334,,77.62,AAB,-1.31233,0.0500837,0.00482205,0.917098 beta-lactamase_2500_T131C,beta-lactamase_2500_131,TEM-1,beta-lactamase_2500,P62593,0.917102,NO,131,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.328,-3.123,1.795,,,H,A,0.22,-0.69,3.048,,67.48,PPH,-1.00867,0.361275,0.00345886,0.917102 WW_domain_I193S,WW_domain_193,Yap65,WW_domain,P46937,0.917102,NO,193,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.993,-3.366,1.373,6.15906,,,,,,1.833,,83.33,BHA,-1.756,0.153962,0.00587613,0.917102 beta-lactamase_P253R,beta-lactamase_253,TEM-1,beta-lactamase,P62593,0.917145,NO,253,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-2.253,-3.013,0.76,5.24842,0.308,,B,0.73,-0.46,2.293,,73.08,BOP,-2.10633,0.221079,0.00786358,0.917145 beta-lactamase_L111W,beta-lactamase_111,TEM-1,beta-lactamase,P62593,0.917172,NO,111,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.76,-5.305,3.545,5.8705,0.328,T,A,0.84,0.93,3.836,,64.34,BHP,-1.884,0.221079,0.00480671,0.917172 beta-lactamase_L137F,beta-lactamase_137,TEM-1,beta-lactamase,P62593,0.917172,NO,137,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.03,-3.682,2.652,5.20117,,H,A,1.07,-0.38,0.674,,42.31,HHP,-1.58933,0.221079,0.00278599,0.917172 beta-lactamase_0_A133Q,beta-lactamase_0_133,TEM-1,beta-lactamase_0,P62593,0.917195,NO,133,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.186,-4.056,2.87,,,H,A,0.46,-0.86,2.148,,67.83,HHP,-0.988333,0.0500837,0.00468022,0.917195 PSD95pdz3_S350W,PSD95pdz3_350,PSD95pdz3,PSD95pdz3,P31016,0.917225,NO,350,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.519,-5.004,3.485,4.97629,,,,,25.01,,,,HPO,-1.29133,0.0758425,0.000704883,0.917225 beta-lactamase_T147D,beta-lactamase_147,TEM-1,beta-lactamase,P62593,0.917277,NO,147,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.149,-3.491,2.342,5.37474,0.281,H,A,0.8,-0.68,2.838,,64.34,HPH,-1.456,0.221079,0.00226017,0.917277 beta-lactamase_0_L167E,beta-lactamase_0_167,TEM-1,beta-lactamase_0,P62593,0.917321,NO,167,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.138,-3.783,2.645,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.0500837,0.00303566,0.917321 beta-lactamase_0_L111I,beta-lactamase_0_111,TEM-1,beta-lactamase_0,P62593,0.917356,NO,111,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.76,-2.153,0.393,,0.328,T,A,0.55,0.93,1.966,,64.34,BHP,-1.884,0.0500837,0.00480671,0.917356 kka2_1:4_R121L,kka2_1:4_121,Kka2,kka2_1:4,P00552,0.917364,NO,121,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.552,-2.477,0.925,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.168804,0.00523326,0.917364 Pab1_D151R,Pab1_151,Pab1,Pab1,P04147,0.917365,NO,151,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.399,-2.271,-0.128,,,,,,,,,,OAH,-1.51767,0.175299,0.00228155,0.917365 beta-lactamase_0_A235L,beta-lactamase_0_235,TEM-1,beta-lactamase_0,P62593,0.917398,NO,235,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.266,-3.325,2.059,,0.32,E,B,0.46,-0.86,2.261,,50,OHO,-0.89,0.0500837,0.00493474,0.917398 beta-lactamase_625_P143I,beta-lactamase_625_143,TEM-1,beta-lactamase_625,P62593,0.917411,NO,143,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.967,-2.787,1.82,,0.075,H,A,0.52,-0.37,1.445,,66.78,OOB,-1.354,0.213352,0.00114551,0.917411 beta-lactamase_2500_H24E,beta-lactamase_2500_24,TEM-1,beta-lactamase_2500,P62593,0.917422,NO,24,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-2.481,-3.284,0.803,,,,,,,0.467,,93.01,OBO,-2.0035,0.361275,0.00238894,0.917422 beta-lactamase_0_D231C,beta-lactamase_0_231,TEM-1,beta-lactamase_0,P62593,0.917439,NO,231,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.816,-5.136,4.32,,,E,B,0.75,-1.06,4.975,,65.38,HAB,-0.994,0.0500837,0.00107395,0.917439 kka2_1:1_Q42P,kka2_1:1_42,Kka2,kka2_1:1,P00552,0.917536,NO,42,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.907,-2.271,-0.636,,1.044,T,B,0.4,-0.8,2.792,,71.59,HPO,-2.12433,0.520039,0.00679212,0.917536 kka2_1:2_A229Q,kka2_1:2_229,Kka2,kka2_1:2,P00552,0.917545,NO,229,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.739,-3.175,1.436,,0.32,H,A,0.46,-0.7,6.549,,63.64,HHA,-1.851,0.295029,0.00942138,0.917545 beta-lactamase_2500_E238I,beta-lactamase_2500_238,TEM-1,beta-lactamase_2500,P62593,0.917546,NO,238,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.361275,0.00743256,0.917546 beta-lactamase_A276E,beta-lactamase_276,TEM-1,beta-lactamase,P62593,0.917556,NO,276,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.144,-3.439,2.295,5.1387,0.117,H,A,0.52,-0.84,1.283,,44.06,HHA,-1.47,0.221079,0.0191712,0.917556 beta-lactamase_F17G,beta-lactamase_17,TEM-1,beta-lactamase,P62593,0.917556,NO,17,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-2.337,-3.52,1.183,,,,,,,2.192,,67.83,HHO,-2.17733,0.221079,0.00216499,0.917556 beta-lactamase_L100F,beta-lactamase_100,TEM-1,beta-lactamase,P62593,0.917556,NO,100,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.218,-3.677,2.459,5.60291,0.343,,B,1.3,0.13,1.173,,63.29,AHH,-1.23467,0.221079,0.00413885,0.917556 beta-lactamase_0_R91E,beta-lactamase_0_91,TEM-1,beta-lactamase_0,P62593,0.917573,NO,91,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.392,-2.211,0.819,,0.444,,B,1.2,0.96,4.557,,50.35,OBB,-1.73367,0.0500837,0.00380226,0.917573 kka2_1:2_L170M,kka2_1:2_170,Kka2,kka2_1:2,P00552,0.917589,NO,170,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.28,-3.089,1.809,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.295029,0.00730791,0.917589 beta-lactamase_156_T131Q,beta-lactamase_156_131,TEM-1,beta-lactamase_156,P62593,0.917598,NO,131,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.328,-3.951,2.623,,,H,A,0.22,-0.69,2.031,,67.48,PPH,-1.00867,0.111618,0.00345886,0.917598 PSD95pdz3_F337G,PSD95pdz3_337,PSD95pdz3,PSD95pdz3,P31016,0.917667,NO,337,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.524,-3.265,1.741,5.22838,,,,,13.4936,,,,HHH,-1.59467,0.0758425,0.000875287,0.917667 beta-lactamase_625_L150Q,beta-lactamase_625_150,TEM-1,beta-lactamase_625,P62593,0.917741,NO,150,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.326,-4.106,2.78,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.213352,0.00463171,0.917741 beta-lactamase_0_G85Q,beta-lactamase_0_85,TEM-1,beta-lactamase_0,P62593,0.917756,NO,85,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.011,-3.928,2.917,,0.805,T,l,0.29,1.7,2.25,,63.64,HOP,-1.68733,0.0500837,0.00252173,0.917756 beta-lactamase_0_D129L,beta-lactamase_0_129,TEM-1,beta-lactamase_0,P62593,0.91778,NO,129,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.816,-3.806,2.99,,,,B,0.75,-0.69,2.66,,34.97,PAP,-0.818,0.0500837,0.00109178,0.91778 beta-lactamase_39_M115C,beta-lactamase_39_115,TEM-1,beta-lactamase_39,P62593,0.917783,NO,115,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.389,-4.767,3.378,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.0495842,0.0034337,0.917783 PSD95pdz3_I316E,PSD95pdz3_316,PSD95pdz3,PSD95pdz3,P31016,0.917811,NO,316,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.63,-3.572,1.942,5.46166,,,,,19.005,,,,HHB,-1.62733,0.0758425,0.00112762,0.917811 beta-lactamase_39_S241K,beta-lactamase_39_241,TEM-1,beta-lactamase_39,P62593,0.917839,NO,241,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.0495842,0.00452736,0.917839 beta-lactamase_39_E119V,beta-lactamase_39_119,TEM-1,beta-lactamase_39,P62593,0.917845,NO,119,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.412,-3.661,2.249,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.0495842,0.00386966,0.917845 kka2_1:8_Q4H,kka2_1:8_4,Kka2,kka2_1:8,P00552,0.917849,NO,4,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.361,-4.16,1.799,,,,,,,2.026,,71.59,APA,-1.95533,0.100394,0.00239179,0.917849 kka2_1:8_Q4H,kka2_1:8_4,Kka2,kka2_1:8,P00552,0.917849,NO,4,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.361,-4.16,1.799,,,,,,,2.026,,71.59,APA,-1.95533,0.100394,0.00239179,0.917849 beta-lactamase_D113C,beta-lactamase_113,TEM-1,beta-lactamase,P62593,0.917858,NO,113,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.829,-5.156,3.327,6.04499,0.665,T,A,0.23,0.91,21.104,21.104,73.08,PAO,-1.703,0.221079,0.00474112,0.917858 beta-lactamase_R176C,beta-lactamase_176,TEM-1,beta-lactamase,P62593,0.917858,NO,176,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-0.863,-5.087,4.224,5.61264,0.385,T,B,0.68,-0.63,,,,ABA,-1.38867,0.221079,0.00105554,0.917858 beta-lactamase_S221W,beta-lactamase_221,TEM-1,beta-lactamase,P62593,0.917858,NO,221,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.754,-5.418,3.664,5.77407,0.624,H,A,0.74,-0.2,0.383,,74.48,BPH,-1.59967,0.221079,0.0046094,0.917858 beta-lactamase_0_E279C,beta-lactamase_0_279,TEM-1,beta-lactamase_0,P62593,0.917869,NO,279,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.0500837,0.0192826,0.917869 beta-lactamase_39_E272K,beta-lactamase_39_272,TEM-1,beta-lactamase_39,P62593,0.917876,NO,272,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.127,,,,0.081,H,A,0.43,-0.97,12.983,12.983,63.64,AAB,-1.56333,0.0495842,0.00545371,0.917876 hsp90_S586N,hsp90_586,hsp90,hsp90,P02829,0.917927,NO,586,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.764,-3.051,0,4.65438,,,B,0.93,0.15,,,,HPH,-3.157,0.368192,0.000222939,0.917927 kka2_1:8_D134C,kka2_1:8_134,Kka2,kka2_1:8,P00552,0.917967,NO,134,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.969,-5.129,4.16,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.100394,0.00270812,0.917967 kka2_1:8_D134C,kka2_1:8_134,Kka2,kka2_1:8,P00552,0.917967,NO,134,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.969,-5.129,4.16,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.100394,0.00270812,0.917967 Pab1_M189E,Pab1_189,Pab1,Pab1,P04147,0.917982,NO,189,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.406,-3.482,2.076,,0.631,E,b,,2.81,,,,OHH,-1.18,0.175299,0.000278756,0.917982 kka2_1:4_P45V,kka2_1:4_45,Kka2,kka2_1:4,P00552,0.918007,NO,45,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.774,-3.689,1.915,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.168804,0.00590481,0.918007 PSD95pdz3_L367M,PSD95pdz3_367,PSD95pdz3,PSD95pdz3,P31016,0.91801,NO,367,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.347,-3.487,2.14,5.47696,,,,,17.0063,,,,AHB,-1.39767,0.0758425,0.000466436,0.91801 beta-lactamase_2500_V101K,beta-lactamase_2500_101,TEM-1,beta-lactamase_2500,P62593,0.918011,NO,101,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.295,-3.742,2.447,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.361275,0.00374492,0.918011 PSD95pdz3_Y392G,PSD95pdz3_392,PSD95pdz3,PSD95pdz3,P31016,0.918047,NO,392,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-1.437,-3.265,1.828,5.20337,,,,,11.725,,,,PHB,-1.51733,0.0758425,0.000935211,0.918047 PSD95pdz3_E331S,PSD95pdz3_331,PSD95pdz3,PSD95pdz3,P31016,0.91806,NO,331,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.404,-2.842,1.438,5.86289,,,,,51.8889,,,,OAA,-1.22533,0.0758425,0.000950134,0.91806 Pab1_G167F,Pab1_167,Pab1,Pab1,P04147,0.918064,NO,167,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.223,-4.158,2.935,,0.195,S,g,,0.03,,,,BOH,-1.25133,0.175299,0.00146449,0.918064 beta-lactamase_0_R202P,beta-lactamase_0_202,TEM-1,beta-lactamase_0,P62593,0.918088,NO,202,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.292,-3.859,2.567,,0.188,H,A,1.2,0.62,7.016,,77.62,PBP,-1.54767,0.0500837,0.00321899,0.918088 beta-lactamase_R202V,beta-lactamase_202,TEM-1,beta-lactamase,P62593,0.918103,NO,202,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.292,-3.679,2.387,5.16273,0.188,H,A,0.68,0.62,1.918,,77.62,PBP,-1.54767,0.221079,0.00321899,0.918103 beta-lactamase_2500_L160T,beta-lactamase_2500_160,TEM-1,beta-lactamase_2500,P62593,0.918176,NO,160,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.977,-3.438,2.461,,0.022,,B,0.55,-0.6,0.895,,44.41,BHA,-0.936,0.361275,0.00193775,0.918176 beta-lactamase_0_A84P,beta-lactamase_0_84,TEM-1,beta-lactamase_0,P62593,0.918189,NO,84,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.651,-3.933,2.282,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.0500837,0.00503822,0.918189 beta-lactamase_0_V260H,beta-lactamase_0_260,TEM-1,beta-lactamase_0,P62593,0.91819,NO,260,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.0500837,0.00471757,0.91819 beta-lactamase_0_G194T,beta-lactamase_0_194,TEM-1,beta-lactamase_0,P62593,0.918201,NO,194,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.396,-2.79,1.394,,0.276,S,b,0.29,0.36,3.017,,67.83,POA,-1.832,0.0500837,0.00392163,0.918201 Pab1_F149I,Pab1_149,Pab1,Pab1,P04147,0.918245,NO,149,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.149,-3.152,2.003,,0.183,T,A,1.33,1.09,,,,HHO,-1.27767,0.175299,0.000325688,0.918245 kka2_1:2_P249Q,kka2_1:2_249,Kka2,kka2_1:2,P00552,0.918251,NO,249,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.867,-4.234,2.367,,0.406,.,B,0.52,-0.01,0.76,,92.05,HOA,-1.66867,0.295029,0.011045,0.918251 beta-lactamase_2500_P172W,beta-lactamase_2500_172,TEM-1,beta-lactamase_2500,P62593,0.918259,NO,172,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.998,-5.528,4.53,,0.639,T,b,0.52,0.24,4.99,,74.48,HOP,-2.03067,0.361275,0.00312594,0.918259 kka2_1:8_R122N,kka2_1:8_122,Kka2,kka2_1:8,P00552,0.918261,NO,122,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.175,-2.97,0.795,,0.487,H,A,1.2,0.26,22.675,22.675,71.59,BBH,-1.53833,0.100394,0.00736512,0.918261 kka2_1:8_R122N,kka2_1:8_122,Kka2,kka2_1:8,P00552,0.918261,NO,122,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.175,-2.97,0.795,,0.487,H,A,1.2,0.26,22.675,22.675,71.59,BBH,-1.53833,0.100394,0.00736512,0.918261 beta-lactamase_0_L135W,beta-lactamase_0_135,TEM-1,beta-lactamase_0,P62593,0.918295,NO,135,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.002,-5.166,4.164,,0.117,H,A,0.55,-0.58,0.705,,43.71,PHH,-1.03767,0.0500837,0.00244423,0.918295 PSD95pdz3_N381E,PSD95pdz3_381,PSD95pdz3,PSD95pdz3,P31016,0.918297,NO,381,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-1.41,-2.897,1.487,5.66057,,,,,28.2162,,,,BPH,-1.37767,0.0758425,0.000265374,0.918297 beta-lactamase_V78M,beta-lactamase_78,TEM-1,beta-lactamase,P62593,0.918305,NO,78,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.459,-2.823,1.364,4.79197,,H,A,0.96,-0.47,1.132,,63.64,HHH,-1.17833,0.221079,0.00492501,0.918305 beta-lactamase_2500_W163R,beta-lactamase_2500_163,TEM-1,beta-lactamase_2500,P62593,0.91835,NO,163,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-1.843,-2.51,0.667,,0.467,,B,0.47,-0.5,32.624,32.624,63.99,BHA,-1.269,0.361275,0.00418955,0.91835 Pab1_I183N,Pab1_183,Pab1,Pab1,P04147,0.918372,NO,183,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.302,-3.993,2.691,,0.308,T,B,1,1.08,1.29,,75.56,HHA,-1.27167,0.175299,0.000574345,0.918372 beta-lactamase_H110Q,beta-lactamase_110,TEM-1,beta-lactamase,P62593,0.918394,NO,110,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-1.706,-2.734,1.028,5.52635,0.341,G,a,0.35,1.08,31.31,31.31,64.69,BBH,-1.73333,0.221079,0.00441499,0.918394 beta-lactamase_H285K,beta-lactamase_285,TEM-1,beta-lactamase,P62593,0.918394,NO,285,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-1.845,-3.347,1.502,5.64289,0.312,T,a,0.35,0.64,1.401,,72.73,BBH,-1.64567,0.221079,0.101555,0.918394 beta-lactamase_2500_A123S,beta-lactamase_2500_123,TEM-1,beta-lactamase_2500,P62593,0.918412,NO,123,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.834,-3.019,2.185,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.361275,0.0010157,0.918412 Pab1_E176H,Pab1_176,Pab1,Pab1,P04147,0.918426,NO,176,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.003,-4.52,2.517,,,,,,,,,,AAO,-2.09933,0.175299,0.00264426,0.918426 kka2_1:4_L47N,kka2_1:4_47,Kka2,kka2_1:4,P00552,0.918441,NO,47,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.265,-4.107,2.842,,0.139,E,B,0.55,-0.86,2.369,,63.26,HHH,-1.77933,0.168804,0.00509386,0.918441 beta-lactamase_0_K254H,beta-lactamase_0_254,TEM-1,beta-lactamase_0,P62593,0.91845,NO,254,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.0500837,0.00369,0.91845 beta-lactamase_I140Y,beta-lactamase_140,TEM-1,beta-lactamase,P62593,0.918475,NO,140,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.733,-3.996,2.263,5.29918,0.128,H,A,1,0.41,1.16,,73.08,PHO,-1.48733,0.221079,0.00597777,0.918475 beta-lactamase_T147C,beta-lactamase_147,TEM-1,beta-lactamase,P62593,0.918475,NO,147,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.149,-4.804,3.655,5.37474,0.281,H,A,0.8,-0.68,2.838,,64.34,HPH,-1.456,0.221079,0.00226017,0.918475 Pab1_F146T,Pab1_146,Pab1,Pab1,P04147,0.918506,NO,146,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.149,-3.464,2.315,,0.006,H,A,,0.75,,,,PHP,-1.161,0.175299,0.000329265,0.918506 Pab1_I130A,Pab1_130,Pab1,Pab1,P04147,0.918506,NO,130,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.212,-2.895,1.683,,,E,B,1.23,0.01,,,,HHB,-1.188,0.175299,0.000351112,0.918506 beta-lactamase_625_G265K,beta-lactamase_625_265,TEM-1,beta-lactamase_625,P62593,0.918508,NO,265,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.213352,0.00811926,0.918508 kka2_1:2_L152V,kka2_1:2_152,Kka2,kka2_1:2,P00552,0.918518,NO,152,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.521,-2.421,0.9,,0.547,.,A,0.55,1.36,4.526,,63.64,OHH,-1.162,0.295029,0.00674868,0.918518 beta-lactamase_0_I245K,beta-lactamase_0_245,TEM-1,beta-lactamase_0,P62593,0.91855,NO,245,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.0500837,0.00391032,0.91855 PSD95pdz3_R318H,PSD95pdz3_318,PSD95pdz3,PSD95pdz3,P31016,0.918558,NO,318,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.582,-3.912,2.33,4.94876,,,,,17.5609,,,,BBO,-1.40567,0.0758425,0.00110471,0.918558 beta-lactamase_0_I54A,beta-lactamase_0_54,TEM-1,beta-lactamase_0,P62593,0.918662,NO,54,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-2.838,-2.597,-0.241,,0.669,E,B,0.48,-0.14,0.541,,73.78,BHH,-2.337,0.0500837,0.00403589,0.918662 beta-lactamase_156_E56W,beta-lactamase_156_56,TEM-1,beta-lactamase_156,P62593,0.918663,NO,56,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.043,-5.293,3.25,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.111618,0.00238534,0.918663 Pab1_K164A,Pab1_164,Pab1,Pab1,P04147,0.918672,NO,164,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-2.298,-3.131,0.833,,,,,,,,,,OBP,-1.41767,0.175299,0.00255241,0.918672 beta-lactamase_2500_A222Y,beta-lactamase_2500_222,TEM-1,beta-lactamase_2500,P62593,0.918673,NO,222,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.103,-4.186,2.083,,0.233,H,A,0.46,-0.25,0.379,,77.62,PHH,-1.63733,0.361275,0.00466094,0.918673 Pab1_Y197K,Pab1_197,Pab1,Pab1,P04147,0.918699,NO,197,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-1.345,-3.677,2.332,,,,,,,0.891,,80.42,HHH,-1.41767,0.175299,0.00302474,0.918699 beta-lactamase_D99L,beta-lactamase_99,TEM-1,beta-lactamase,P62593,0.918705,NO,99,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.191,-3.588,2.397,5.66081,0.402,G,A,0.23,0.36,1.318,,64.69,PAH,-1.794,0.221079,0.00305446,0.918705 kka2_1:2_L7H,kka2_1:2_7,Kka2,kka2_1:2,P00552,0.91874,NO,7,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.926,-2.581,0.655,,,,,,,3.012,,71.59,OHB,-2.12333,0.295029,0.00269456,0.91874 beta-lactamase_0_L49K,beta-lactamase_0_49,TEM-1,beta-lactamase_0,P62593,0.918746,NO,49,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.897,-3.583,1.686,,0.131,T,A,0.55,0.04,13.838,13.838,64.69,AHP,-1.99233,0.0500837,0.00401477,0.918746 beta-lactamase_0_M184N,beta-lactamase_0_184,TEM-1,beta-lactamase_0,P62593,0.918752,NO,184,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.593,-4.028,2.435,,,H,A,0.55,-0.87,13.292,13.292,62.94,HHH,-1.41,0.0500837,0.00356019,0.918752 beta-lactamase_0_L74N,beta-lactamase_0_74,TEM-1,beta-lactamase_0,P62593,0.918815,NO,74,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.296,-4.114,2.818,,,H,A,0.55,-0.91,1.46,,50,HHO,-1.34933,0.0500837,0.00493255,0.918815 beta-lactamase_V82S,beta-lactamase_82,TEM-1,beta-lactamase,P62593,0.918843,NO,82,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.325,-3.501,2.176,5.27777,0.267,H,A,0.96,0.08,1.379,,93.01,BHA,-1.28567,0.221079,0.00397046,0.918843 beta-lactamase_S51G,beta-lactamase_51,TEM-1,beta-lactamase,P62593,0.918854,NO,51,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.526,-2.569,1.043,5.06164,0.496,T,A,0.25,0.26,1.699,,72.73,PPO,-1.88467,0.221079,0.00504821,0.918854 beta-lactamase_Y103Y,beta-lactamase_103,TEM-1,beta-lactamase,P62593,0.918854,NO,103,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-1.33,-1.33,,5.71734,0.613,S,l,2.55,1.21,5.721,,63.29,AHP,-1.48767,0.221079,0.00443048,0.918854 gb1_V280W,gb1_280,gb1,gb1,P06654,0.918872,NO,280,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.764,-5.127,3.363,,,,,,,0.874,,35.71,PHP,-1.63733,0.177985,0.00321577,0.918872 gb1_Y229M,gb1_229,gb1,gb1,P06654,0.918872,NO,229,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-1.282,-4.215,2.933,,,,,,,,,,PHB,-1.4915,0.177985,0.00366605,0.918872 Pab1_L186S,Pab1_186,Pab1,Pab1,P04147,0.918922,NO,186,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.783,-3.556,1.773,,,,,,,,,,HHP,-1.56967,0.175299,0.00154968,0.918922 PSD95pdz3_G322W,PSD95pdz3_322,PSD95pdz3,PSD95pdz3,P31016,0.918926,NO,322,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.008,-4.779,3.771,5.24791,,,,,16.3275,,,,POH,-1.24867,0.0758425,0.00105821,0.918926 beta-lactamase_2500_Q88C,beta-lactamase_2500_88,TEM-1,beta-lactamase_2500,P62593,0.918935,NO,88,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.086,-5.138,3.052,,0.807,,B,0.64,2.03,1.84,,77.62,APH,-1.53433,0.361275,0.00504167,0.918935 kka2_1:2_E199V,kka2_1:2_199,Kka2,kka2_1:2,P00552,0.918935,NO,199,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.234,-2.91,0.676,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.295029,0.00854122,0.918935 beta-lactamase_156_L248Y,beta-lactamase_156_248,TEM-1,beta-lactamase_156,P62593,0.918954,NO,248,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.111618,0.00428493,0.918954 beta-lactamase_0_G216E,beta-lactamase_0_216,TEM-1,beta-lactamase_0,P62593,0.918956,NO,216,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.477,-2.451,0.974,,0.437,I,A,0.29,-0.58,0.834,,74.48,HOO,-1.68067,0.0500837,0.00639568,0.918956 kka2_1:1_A166S,kka2_1:1_166,Kka2,kka2_1:1,P00552,0.918984,NO,166,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.407,-1.802,-0.605,,0.534,.,B,0.46,1.03,1.147,,71.59,HHO,-2.421,0.520039,0.00799912,0.918984 beta-lactamase_625_R273P,beta-lactamase_625_273,TEM-1,beta-lactamase_625,P62593,0.919053,NO,273,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.314,-2.669,0.355,,0.564,H,A,1.2,1.57,1.455,,73.78,ABP,-1.841,0.213352,0.0077952,0.919053 beta-lactamase_39_N130L,beta-lactamase_39_130,TEM-1,beta-lactamase_39,P62593,0.919081,NO,130,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-0.798,-3.583,2.785,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.0495842,0.000683376,0.919081 beta-lactamase_0_V157P,beta-lactamase_0_157,TEM-1,beta-lactamase_0,P62593,0.9191,NO,157,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.751,-4.03,2.279,,0.308,S,a,0.44,-0.75,3.106,,69.58,BHP,-2.00767,0.0500837,0.00506849,0.9191 beta-lactamase_0_A34L,beta-lactamase_0_34,TEM-1,beta-lactamase_0,P62593,0.919113,NO,34,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.059,-2.191,0.132,,,H,A,0.46,-0.54,3.998,,73.78,AHA,-1.74967,0.0500837,0.00407913,0.919113 gb1_T281F,gb1_281,gb1,gb1,P06654,0.919138,NO,281,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.828,-4.001,2.173,,,,,,,1.038,,35.71,HPA,-1.63667,0.177985,0.00284418,0.919138 beta-lactamase_G226Q,beta-lactamase_226,TEM-1,beta-lactamase,P62593,0.919177,NO,226,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.461,-3.959,2.498,5.70682,0.701,T,l,0.77,-0.25,3.199,,74.48,HOH,-1.42933,0.221079,0.00665294,0.919177 beta-lactamase_0_R239E,beta-lactamase_0_239,TEM-1,beta-lactamase_0,P62593,0.919226,NO,239,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.0500837,0.00213852,0.919226 kka2_1:1_G233V,kka2_1:1_233,Kka2,kka2_1:1,P00552,0.919231,NO,233,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.748,-3.827,3.079,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.520039,0.00232366,0.919231 kka2_1:1_A65C,kka2_1:1_65,Kka2,kka2_1:1,P00552,0.919261,NO,65,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.744,-5.062,3.318,,0.437,H,A,0.46,-0.39,3.012,,63.64,HHB,-1.38733,0.520039,0.00709258,0.919261 beta-lactamase_0_T147H,beta-lactamase_0_147,TEM-1,beta-lactamase_0,P62593,0.919275,NO,147,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.149,-4.643,3.494,,0.281,H,A,0.22,-0.68,3.487,,64.34,HPH,-1.456,0.0500837,0.00226017,0.919275 Ubiquitin_A28W,Ubiquitin_28,Uba1,Ubiquitin,P0CG48,0.919355,NO,28,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.895,-5.479,3.584,4.73736,0.369,H,A,,-0.11,,,,BHB,-1.47667,0.205827,0.000842053,0.919355 Ubiquitin_D21V,Ubiquitin_21,Uba1,Ubiquitin,P0CG48,0.919355,NO,21,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.193,-3.644,2.451,4.96432,0.165,,B,0.23,-0.53,1.013,,71.82,PAP,-1.35867,0.205827,0.000465257,0.919355 Ubiquitin_D24H,Ubiquitin_24,Uba1,Ubiquitin,P0CG48,0.919355,NO,24,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,,,,,,,,,,,,,HAP,,0.205827,0.0066591,0.919355 Ubiquitin_D24P,Ubiquitin_24,Uba1,Ubiquitin,P0CG48,0.919355,NO,24,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,,,,,,,,,,,,,HAP,,0.205827,0.0066591,0.919355 Ubiquitin_D24Q,Ubiquitin_24,Uba1,Ubiquitin,P0CG48,0.919355,NO,24,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,,,,,,,,,,,,,HAP,,0.205827,0.0066591,0.919355 Ubiquitin_D32Q,Ubiquitin_32,Uba1,Ubiquitin,P0CG48,0.919355,NO,32,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.451,-2.827,1.376,4.96502,0.835,H,A,,1.4,,,,PAB,-1.47067,0.205827,0.000758819,0.919355 Ubiquitin_D32S,Ubiquitin_32,Uba1,Ubiquitin,P0CG48,0.919355,NO,32,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.451,-3.224,1.773,4.96502,0.835,H,A,,1.4,,,,PAB,-1.47067,0.205827,0.000758819,0.919355 Ubiquitin_D39F,Ubiquitin_39,Uba1,Ubiquitin,P0CG48,0.919355,NO,39,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.792,-4.197,2.405,5.1607,0.433,G,A,,0.55,,,,OAP,-1.754,0.205827,0.00071409,0.919355 Ubiquitin_D39K,Ubiquitin_39,Uba1,Ubiquitin,P0CG48,0.919355,NO,39,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.792,-3.522,1.73,5.1607,0.433,G,A,,0.55,,,,OAP,-1.754,0.205827,0.00071409,0.919355 Ubiquitin_D39Y,Ubiquitin_39,Uba1,Ubiquitin,P0CG48,0.919355,NO,39,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.792,-3.092,1.3,5.1607,0.433,G,A,,0.55,,,,OAP,-1.754,0.205827,0.00071409,0.919355 Ubiquitin_D52W,Ubiquitin_52,Uba1,Ubiquitin,P0CG48,0.919355,NO,52,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.43,-5.392,3.962,4.75143,0.421,T,A,,0.79,,,,AAO,-1.50267,0.205827,0.000806517,0.919355 Ubiquitin_E34C,Ubiquitin_34,Uba1,Ubiquitin,P0CG48,0.919355,NO,34,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.294,-5.223,3.929,5.02178,0.406,H,A,1.62,0.6,1.295,,35.62,BAO,-1.24933,0.205827,0.000686048,0.919355 Ubiquitin_E34M,Ubiquitin_34,Uba1,Ubiquitin,P0CG48,0.919355,NO,34,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.294,-4.661,3.367,5.02178,0.406,H,A,1.62,0.6,1.295,,35.62,BAO,-1.24933,0.205827,0.000686048,0.919355 Ubiquitin_K33D,Ubiquitin_33,Uba1,Ubiquitin,P0CG48,0.919355,NO,33,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.283,-3.718,2.435,5.08526,0.64,H,A,1.82,1.2,1.509,,51.09,ABA,-1.34267,0.205827,0.000712743,0.919355 Ubiquitin_K6S,Ubiquitin_6,Uba1,Ubiquitin,P0CG48,0.919355,NO,6,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.093,-3.198,2.105,4.84211,0.35,E,B,1.82,-0.62,1.502,,71.82,HBP,-1.36133,0.205827,0.000784795,0.919355 Ubiquitin_L69V,Ubiquitin_69,Uba1,Ubiquitin,P0CG48,0.919355,NO,69,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.445,-2.616,1.171,4.75624,0.051,E,B,2.89,-0.94,7.106,,34.31,BHH,-1.72933,0.205827,0.000919136,0.919355 Ubiquitin_Q41I,Ubiquitin_41,Uba1,Ubiquitin,P0CG48,0.919355,NO,41,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-1.329,-3.799,2.47,4.9201,0.017,E,B,0.12,-0.98,0.812,,30.07,PPB,-1.55067,0.205827,0.000521668,0.919355 Ubiquitin_R54D,Ubiquitin_54,Uba1,Ubiquitin,P0CG48,0.919355,NO,54,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.037,-2.878,0.841,5.14935,0.41,S,B,,0.87,,,,OBP,-1.72667,0.205827,0.000581095,0.919355 Ubiquitin_S65D,Ubiquitin_65,Uba1,Ubiquitin,P0CG48,0.919355,NO,65,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.535,-2.762,1.227,4.99442,0.168,,b,0.25,-0.68,16.756,16.756,33.87,APP,-1.626,0.205827,0.000546776,0.919355 Ubiquitin_T12Y,Ubiquitin_12,Uba1,Ubiquitin,P0CG48,0.919355,NO,12,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.288,-4.038,2.75,4.93973,0.417,E,B,0.8,0.12,2.762,,25.84,BPH,-1.39867,0.205827,0.000657544,0.919355 Ubiquitin_T22C,Ubiquitin_22,Uba1,Ubiquitin,P0CG48,0.919355,NO,22,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.344,-4.766,3.422,4.54389,0.237,B,B,,-0.75,,,,APH,-1.28733,0.205827,0.000535592,0.919355 Ubiquitin_T22E,Ubiquitin_22,Uba1,Ubiquitin,P0CG48,0.919355,NO,22,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.344,-3.431,2.087,4.54389,0.237,B,B,,-0.75,,,,APH,-1.28733,0.205827,0.000535592,0.919355 Ubiquitin_T22Y,Ubiquitin_22,Uba1,Ubiquitin,P0CG48,0.919355,NO,22,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.344,-4.191,2.847,4.54389,0.237,B,B,,-0.75,,,,APH,-1.28733,0.205827,0.000535592,0.919355 Ubiquitin_V17N,Ubiquitin_17,Uba1,Ubiquitin,P0CG48,0.919355,NO,17,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.314,-4.064,2.75,5.26282,0.017,,B,2.78,-0.77,3.239,,71.82,AHA,-1.51833,0.205827,0.000659638,0.919355 Ubiquitin_V70C,Ubiquitin_70,Uba1,Ubiquitin,P0CG48,0.919355,NO,70,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.874,-4.945,3.071,5.29728,0.05,E,B,0.96,-0.97,2.363,,34.31,HHH,-1.65533,0.205827,0.00106871,0.919355 kka2_1:8_Y244A,kka2_1:8_244,Kka2,kka2_1:8,P00552,0.919365,NO,244,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-0.775,-3.331,2.556,,0.066,H,A,1.25,-0.64,,,,HHO,-1.41267,0.100394,0.00453187,0.919365 kka2_1:8_Y244A,kka2_1:8_244,Kka2,kka2_1:8,P00552,0.919365,NO,244,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-0.775,-3.331,2.556,,0.066,H,A,1.25,-0.64,,,,HHO,-1.41267,0.100394,0.00453187,0.919365 beta-lactamase_625_E46C,beta-lactamase_625_46,TEM-1,beta-lactamase_625,P62593,0.919399,NO,46,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.94,-3.249,1.309,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.213352,0.00427568,0.919399 beta-lactamase_0_A183M,beta-lactamase_0_183,TEM-1,beta-lactamase_0,P62593,0.919409,NO,183,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.231,-4.59,3.359,,0.155,H,A,0.46,-0.91,1.48,,77.62,HHH,-1.53367,0.0500837,0.00296631,0.919409 beta-lactamase_0_L73G,beta-lactamase_0_73,TEM-1,beta-lactamase_0,P62593,0.919433,NO,73,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.507,-3.739,2.232,,,H,A,0.55,-0.64,0.877,,67.83,HHH,-1.487,0.0500837,0.00488983,0.919433 kka2_1:2_D23Y,kka2_1:2_23,Kka2,kka2_1:2,P00552,0.919454,NO,23,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.459,-4.392,1.933,,0.695,E,B,0.75,-0.65,18.207,18.207,65.53,HAH,-1.94033,0.295029,0.007195,0.919454 kka2_1:4_S104R,kka2_1:4_104,Kka2,kka2_1:4,P00552,0.919475,NO,104,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.436,-3.063,1.627,,0.536,T,A,0.27,-1.11,0.357,,63.64,HPP,-1.91433,0.168804,0.00555207,0.919475 beta-lactamase_156_K286P,beta-lactamase_156_286,TEM-1,beta-lactamase_156,P62593,0.919486,NO,286,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.111618,,0.919486 kka2_1:4_V198E,kka2_1:4_198,Kka2,kka2_1:4,P00552,0.919492,NO,198,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.719,-2.905,1.186,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.168804,0.00835002,0.919492 kka2_1:1_G6V,kka2_1:1_6,Kka2,kka2_1:1,P00552,0.919531,NO,6,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.685,-3.428,1.743,,,,,,,1.292,,71.59,AOH,-1.639,0.520039,0.00204693,0.919531 beta-lactamase_2500_H287K,beta-lactamase_2500_287,TEM-1,beta-lactamase_2500,P62593,0.919534,NO,287,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,,,,,,,,,,,,,BBH,-1.111,0.361275,,0.919534 E1_Ubiquitin_L73H,E1_Ubiquitin_73,Uba1,E1_Ubiquitin,P0CG63,0.91954,NO,73,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.039,-4.722,3.683,,0.518,,B,1.3,1,,,,BHB,-1.175,0.18783,0.00111236,0.91954 beta-lactamase_2500_Q204K,beta-lactamase_2500_204,TEM-1,beta-lactamase_2500,P62593,0.919561,NO,204,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-1.382,-2.218,0.836,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.361275,0.00364106,0.919561 beta-lactamase_0_Q267F,beta-lactamase_0_267,TEM-1,beta-lactamase_0,P62593,0.919569,NO,267,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.0500837,0.0102128,0.919569 WW_domain_T196M,WW_domain_196,Yap65,WW_domain,P46937,0.91959,NO,196,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.782,-4.407,2.625,5.5744,,,,,,5.836,,70.04,PPP,-1.732,0.153962,0.00421377,0.91959 beta-lactamase_0_G240R,beta-lactamase_0_240,TEM-1,beta-lactamase_0,P62593,0.919591,NO,240,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.0500837,0.00591201,0.919591 beta-lactamase_0_A278V,beta-lactamase_0_278,TEM-1,beta-lactamase_0,P62593,0.919592,NO,278,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.348,,,,0.015,H,A,0.48,-0.85,4.624,,63.29,HHA,-1.41833,0.0500837,0.0310297,0.919592 beta-lactamase_G194L,beta-lactamase_194,TEM-1,beta-lactamase,P62593,0.919602,NO,194,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.396,-3.731,2.335,5.46622,0.276,S,b,0.77,0.36,3.593,,67.83,POA,-1.832,0.221079,0.00392163,0.919602 Pab1_D151P,Pab1_151,Pab1,Pab1,P04147,0.919627,NO,151,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.399,-3.76,1.361,,,,,,,,,,OAH,-1.51767,0.175299,0.00228155,0.919627 PSD95pdz3_A375Y,PSD95pdz3_375,PSD95pdz3,PSD95pdz3,P31016,0.919655,NO,375,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.307,-3.844,2.537,5.05512,,,,,13.888,,,,PHH,-1.43767,0.0758425,0.000356809,0.919655 PSD95pdz3_G324I,PSD95pdz3_324,PSD95pdz3,PSD95pdz3,P31016,0.919655,NO,324,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.008,-3.917,2.909,4.98881,,,,,10.4525,,,,HOH,-1.293,0.0758425,0.00103462,0.919655 PSD95pdz3_G329I,PSD95pdz3_329,PSD95pdz3,PSD95pdz3,P31016,0.919655,NO,329,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.008,-3.917,2.909,4.7671,,,,,19.7075,,,,HOO,-1.16033,0.0758425,0.000974577,0.919655 PSD95pdz3_I327K,PSD95pdz3_327,PSD95pdz3,PSD95pdz3,P31016,0.919655,NO,327,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.63,-3.589,1.959,5.7413,,,,,14.0388,,,,PHH,-1.50167,0.0758425,0.000998774,0.919655 PSD95pdz3_I336Y,PSD95pdz3_336,PSD95pdz3,PSD95pdz3,P31016,0.919655,NO,336,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.63,-3.619,1.989,5.11321,,,,,13.6363,,,,OHH,-1.38733,0.0758425,0.000887923,0.919655 PSD95pdz3_I338K,PSD95pdz3_338,PSD95pdz3,PSD95pdz3,P31016,0.919655,NO,338,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.63,-3.589,1.959,5.45113,,,,,13.0087,,,,HHP,-1.55767,0.0758425,0.000862587,0.919655 PSD95pdz3_I338Y,PSD95pdz3_338,PSD95pdz3,PSD95pdz3,P31016,0.919655,NO,338,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.63,-3.619,1.989,5.45113,,,,,13.0087,,,,HHP,-1.55767,0.0758425,0.000862587,0.919655 PSD95pdz3_I359W,PSD95pdz3_359,PSD95pdz3,PSD95pdz3,P31016,0.919655,NO,359,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.63,-5.004,3.374,5.35151,,,,,14.8012,,,,PHH,-1.58667,0.0758425,0.000580694,0.919655 PSD95pdz3_V362H,PSD95pdz3_362,PSD95pdz3,PSD95pdz3,P31016,0.919655,NO,362,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.465,-4.587,3.122,4.99436,,,,,19.6443,,,,PHP,-1.46467,0.0758425,0.000538527,0.919655 kka2_1:8_I254D,kka2_1:8_254,Kka2,kka2_1:8,P00552,0.919661,NO,254,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.933,-4.156,2.223,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.100394,0.0132375,0.919661 kka2_1:8_I254D,kka2_1:8_254,Kka2,kka2_1:8,P00552,0.919661,NO,254,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.933,-4.156,2.223,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.100394,0.0132375,0.919661 Pab1_Y143D,Pab1_143,Pab1,Pab1,P04147,0.919763,NO,143,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-1.961,-3.577,1.616,,0.409,H,A,,0.3,,,,HHA,-1.39633,0.175299,0.00160364,0.919763 kka2_1:8_R258N,kka2_1:8_258,Kka2,kka2_1:8,P00552,0.919795,NO,258,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.626,-3.818,2.192,,0.316,H,A,0.16,-0.85,5.58,,53.03,HBH,-1.25933,0.100394,0.00983174,0.919795 kka2_1:8_R258N,kka2_1:8_258,Kka2,kka2_1:8,P00552,0.919795,NO,258,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.626,-3.818,2.192,,0.316,H,A,0.16,-0.85,5.58,,53.03,HBH,-1.25933,0.100394,0.00983174,0.919795 Pab1_G126S,Pab1_126,Pab1,Pab1,P04147,0.919812,NO,126,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.985,-2.971,1.986,,0.011,T,A,0.46,-0.07,2.349,,80.42,OOP,-1.032,0.175299,0.00109814,0.919812 beta-lactamase_0_T139Y,beta-lactamase_0_139,TEM-1,beta-lactamase_0,P62593,0.919844,NO,139,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.901,-4.252,2.351,,0.216,H,A,0.22,0.39,0.421,,77.62,PPH,-2.04667,0.0500837,0.00441837,0.919844 beta-lactamase_39_K213H,beta-lactamase_39_213,TEM-1,beta-lactamase_39,P62593,0.919847,NO,213,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.81,-4.552,2.742,,0.67,,A,2.34,0.29,2.648,,67.83,ABH,-1.57767,0.0495842,0.00610411,0.919847 Pab1_S165G,Pab1_165,Pab1,Pab1,P04147,0.919847,NO,165,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.146,-2.725,1.579,,0.12,,a,,0.11,,,,BPB,-1.56867,0.175299,0.000307838,0.919847 beta-lactamase_0_M153I,beta-lactamase_0_153,TEM-1,beta-lactamase_0,P62593,0.919855,NO,153,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-3.193,-1.739,-1.454,,0.14,T,A,0.55,-0.11,3.826,,77.62,PHO,-2.25767,0.0500837,0.00509109,0.919855 beta-lactamase_0_M184D,beta-lactamase_0_184,TEM-1,beta-lactamase_0,P62593,0.919874,NO,184,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.593,-3.936,2.343,,,H,A,0.55,-0.87,13.292,13.292,62.94,HHH,-1.41,0.0500837,0.00356019,0.919874 beta-lactamase_0_E35N,beta-lactamase_0_35,TEM-1,beta-lactamase_0,P62593,0.919891,NO,35,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-0.869,-3.445,2.576,,0.15,H,A,1.04,0.21,0.664,,46.85,HAA,-1.88667,0.0500837,0.00174441,0.919891 gb1_K230E,gb1_230,gb1,gb1,P06654,0.919934,NO,230,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.701,-3.082,1.381,,,,,,,0.166,,11.83,HBH,-1.52867,0.177985,0.00331703,0.919934 beta-lactamase_P217L,beta-lactamase_217,TEM-1,beta-lactamase,P62593,0.919953,NO,217,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-2.062,-3.634,1.572,5.19872,0.496,I,A,0.99,-0.33,0.431,,74.48,OOH,-1.64333,0.221079,0.00463211,0.919953 beta-lactamase_625_P105N,beta-lactamase_625_105,TEM-1,beta-lactamase_625,P62593,0.919977,NO,105,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.813,-3.82,3.007,,0.226,T,A,0.52,0.8,1.154,,63.29,POH,-1.01533,0.213352,0.0011981,0.919977 beta-lactamase_0_N134T,beta-lactamase_0_134,TEM-1,beta-lactamase_0,P62593,0.920002,NO,134,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-0.879,-3.245,2.366,,0.138,H,A,0.61,-0.6,3.776,,53.15,HPH,-1.02233,0.0500837,0.000644786,0.920002 beta-lactamase_0_T178D,beta-lactamase_0_178,TEM-1,beta-lactamase_0,P62593,0.920017,NO,178,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-0.791,-3.469,2.678,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.0500837,0.000684366,0.920017 beta-lactamase_156_P65Q,beta-lactamase_156_65,TEM-1,beta-lactamase_156,P62593,0.920051,NO,65,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.894,-3.954,3.06,,0.098,E,B,0.52,-0.62,0.623,,40.56,HOH,-1.03233,0.111618,0.00152776,0.920051 beta-lactamase_0_P181A,beta-lactamase_0_181,TEM-1,beta-lactamase_0,P62593,0.920089,NO,181,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.813,-2.357,1.544,,,H,A,0.52,-1.14,1.357,,61.54,HOH,-1.795,0.0500837,0.000703122,0.920089 beta-lactamase_625_L191W,beta-lactamase_625_191,TEM-1,beta-lactamase_625,P62593,0.920118,NO,191,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.087,-5.14,4.053,,,H,A,0.55,0.09,1.908,,63.29,BHH,-1.445,0.213352,0.00263549,0.920118 kka2_1:8_D159T,kka2_1:8_159,Kka2,kka2_1:8,P00552,0.92012,NO,159,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.82,-3.513,2.693,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.100394,0.0030485,0.92012 kka2_1:8_D159T,kka2_1:8_159,Kka2,kka2_1:8,P00552,0.92012,NO,159,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.82,-3.513,2.693,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.100394,0.0030485,0.92012 Pab1_T145V,Pab1_145,Pab1,Pab1,P04147,0.920144,NO,145,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.067,-2.896,1.829,,0.237,H,A,0.3,0.69,,,,APH,-1.135,0.175299,0.000331088,0.920144 kka2_1:4_R121H,kka2_1:4_121,Kka2,kka2_1:4,P00552,0.920146,NO,121,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.552,-2.742,1.19,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.168804,0.00523326,0.920146 beta-lactamase_0_D252P,beta-lactamase_0_252,TEM-1,beta-lactamase_0,P62593,0.920151,NO,252,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.0500837,0.00575769,0.920151 beta-lactamase_0_V259T,beta-lactamase_0_259,TEM-1,beta-lactamase_0,P62593,0.920215,NO,259,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.0500837,0.0070773,0.920215 beta-lactamase_0_N168S,beta-lactamase_0_168,TEM-1,beta-lactamase_0,P62593,0.920216,NO,168,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-1.029,-2.37,1.341,,0.113,G,A,0.61,-0.4,0.881,,44.41,HPA,-1.13233,0.0500837,0.00288667,0.920216 beta-lactamase_0_A40G,beta-lactamase_0_40,TEM-1,beta-lactamase_0,P62593,0.920224,NO,40,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.402,-1.32,-0.082,,0.155,S,B,0.46,0.21,0.783,,73.78,OHB,-1.40267,0.0500837,0.00490026,0.920224 beta-lactamase_39_R41E,beta-lactamase_39_41,TEM-1,beta-lactamase_39,P62593,0.920296,NO,41,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-0.942,-3.241,2.299,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.0495842,0.00123327,0.920296 beta-lactamase_0_T193L,beta-lactamase_0_193,TEM-1,beta-lactamase_0,P62593,0.92032,NO,193,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.914,-1.776,-0.138,,0.439,H,a,0.22,0.33,11.546,11.546,63.99,HPO,-1.52133,0.0500837,0.00482669,0.92032 kka2_1:4_G55W,kka2_1:4_55,Kka2,kka2_1:4,P00552,0.920335,NO,55,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.625,-5.446,3.821,,0.517,S,b,0.75,1.19,15.753,15.753,63.64,POH,-2.05967,0.168804,0.00667877,0.920335 Pab1_L142A,Pab1_142,Pab1,Pab1,P04147,0.920393,NO,142,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.039,-2.895,1.856,,0.007,H,A,0.84,-0.65,,,,HHH,-1.487,0.175299,0.000335477,0.920393 beta-lactamase_A266D,beta-lactamase_266,TEM-1,beta-lactamase,P62593,0.92043,NO,266,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.369,-3.804,2.435,5.02057,0.175,S,B,0.52,0.07,1.832,,64.34,PHP,-2.08567,0.221079,0.0140785,0.92043 beta-lactamase_D99I,beta-lactamase_99,TEM-1,beta-lactamase,P62593,0.92043,NO,99,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.191,-3.979,2.788,5.66081,0.402,G,A,0.23,0.36,1.318,,64.69,PAH,-1.794,0.221079,0.00305446,0.92043 beta-lactamase_G39I,beta-lactamase_39,TEM-1,beta-lactamase,P62593,0.92043,NO,39,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.864,-4.195,2.331,5.35574,0.701,T,L,0.23,0.47,29.926,29.926,77.62,HOH,-1.53633,0.221079,0.00487611,0.92043 beta-lactamase_H24W,beta-lactamase_24,TEM-1,beta-lactamase,P62593,0.92043,NO,24,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-2.481,-5.305,2.824,5.82767,,,,,,2.708,,93.01,HBO,-1.85167,0.221079,0.00238894,0.92043 beta-lactamase_H5C,beta-lactamase_5,TEM-1,beta-lactamase,P62593,0.92043,NO,5,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-2.698,-3.114,0.416,,,,,,,1.865,,72.73,PBH,-2.36967,0.221079,0.00292712,0.92043 beta-lactamase_L150T,beta-lactamase_150,TEM-1,beta-lactamase,P62593,0.92043,NO,150,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.326,-2.5,1.174,5.15566,,H,A,1.75,-0.2,1.615,,62.94,HHB,-1.86167,0.221079,0.00463171,0.92043 beta-lactamase_P60Y,beta-lactamase_60,TEM-1,beta-lactamase,P62593,0.92043,NO,60,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-2.469,-4.292,1.823,5.51353,0.256,T,A,0.73,-0.56,3.653,,77.62,BOA,-1.97633,0.221079,0.00521318,0.92043 beta-lactamase_R202C,beta-lactamase_202,TEM-1,beta-lactamase,P62593,0.92043,NO,202,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.292,-5.047,3.755,5.16273,0.188,H,A,0.68,0.62,1.918,,77.62,PBP,-1.54767,0.221079,0.00321899,0.92043 beta-lactamase_R7I,beta-lactamase_7,TEM-1,beta-lactamase,P62593,0.92043,NO,7,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.683,-3.56,1.877,,,,,,,2.44,,67.13,HBH,-1.96267,0.221079,0.00211375,0.92043 beta-lactamase_S2W,beta-lactamase_2,TEM-1,beta-lactamase,P62593,0.92043,NO,2,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.942,-5.257,3.315,,,,,,,2.36,,65.38,HPH,-2.02767,0.221079,0.00227352,0.92043 beta-lactamase_V72T,beta-lactamase_72,TEM-1,beta-lactamase,P62593,0.92043,NO,72,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.658,-2.757,1.099,5.80324,,H,A,2.78,-1.03,2.964,,65.73,BHH,-1.32167,0.221079,0.00501194,0.92043 beta-lactamase_Y44M,beta-lactamase_44,TEM-1,beta-lactamase,P62593,0.92043,NO,44,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-2.547,-2.521,-0.026,5.6273,,E,B,2.55,-0.45,2.683,,73.78,OHH,-1.86267,0.221079,0.00426364,0.92043 kka2_1:8_A34R,kka2_1:8_34,Kka2,kka2_1:8,P00552,0.920434,NO,34,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.928,-3.768,2.84,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.100394,0.00343484,0.920434 kka2_1:8_A34R,kka2_1:8_34,Kka2,kka2_1:8,P00552,0.920434,NO,34,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.928,-3.768,2.84,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.100394,0.00343484,0.920434 beta-lactamase_0_D99V,beta-lactamase_0_99,TEM-1,beta-lactamase_0,P62593,0.920446,NO,99,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.191,-3.648,2.457,,0.402,G,A,0.75,0.36,0.374,,64.69,PAH,-1.794,0.0500837,0.00305446,0.920446 kka2_1:8_V214K,kka2_1:8_214,Kka2,kka2_1:8,P00552,0.920466,NO,214,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.261,-3.816,2.555,,0.117,E,B,1.48,-0.31,1.859,,64.39,OHH,-0.941667,0.100394,0.00692782,0.920466 kka2_1:8_V214K,kka2_1:8_214,Kka2,kka2_1:8,P00552,0.920466,NO,214,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.261,-3.816,2.555,,0.117,E,B,1.48,-0.31,1.859,,64.39,OHH,-0.941667,0.100394,0.00692782,0.920466 kka2_1:2_T225I,kka2_1:2_225,Kka2,kka2_1:2,P00552,0.920488,NO,225,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.393,-3.64,1.247,,0.036,H,A,0.22,-1.22,4.554,,63.64,HPB,-1.58733,0.295029,0.0113598,0.920488 Pab1_L153Q,Pab1_153,Pab1,Pab1,P04147,0.920488,NO,153,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.039,-3.941,2.902,,0.46,E,A,,-0.95,,,,HHP,-1.17667,0.175299,0.000321212,0.920488 kka2_1:2_A110V,kka2_1:2_110,Kka2,kka2_1:2,P00552,0.92056,NO,110,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.064,-2.939,0.875,,0.175,H,A,0.46,-1.19,23.237,23.237,71.59,OHA,-1.91867,0.295029,0.00759851,0.92056 PSD95pdz3_A382L,PSD95pdz3_382,PSD95pdz3,PSD95pdz3,P31016,0.920615,NO,382,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.307,-2.815,1.508,5.30282,,,,,22.472,,,,PHO,-1.24167,0.0758425,0.000249256,0.920615 kka2_1:8_L174M,kka2_1:8_174,Kka2,kka2_1:8,P00552,0.920623,NO,174,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.952,-2.955,2.003,,,H,A,1.59,-0.31,1.204,,51.89,BHB,-2.08533,0.100394,0.00438501,0.920623 kka2_1:8_L174M,kka2_1:8_174,Kka2,kka2_1:8,P00552,0.920623,NO,174,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.952,-2.955,2.003,,,H,A,1.59,-0.31,1.204,,51.89,BHB,-2.08533,0.100394,0.00438501,0.920623 beta-lactamase_39_D177E,beta-lactamase_39_177,TEM-1,beta-lactamase_39,P62593,0.92066,NO,177,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.967,-2.98,2.013,,0.006,T,L,0.75,-1.02,3.536,,64.69,BAP,-0.873667,0.0495842,0.000864022,0.92066 beta-lactamase_0_N168P,beta-lactamase_0_168,TEM-1,beta-lactamase_0,P62593,0.920722,NO,168,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-1.029,-3.858,2.829,,0.113,G,A,0.61,-0.4,0.881,,44.41,HPA,-1.13233,0.0500837,0.00288667,0.920722 kka2_1:2_R122S,kka2_1:2_122,Kka2,kka2_1:2,P00552,0.920745,NO,122,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.175,-2.833,0.658,,0.487,H,A,1.2,0.26,16.436,16.436,71.59,BBH,-1.53833,0.295029,0.00736512,0.920745 beta-lactamase_0_I125T,beta-lactamase_0_125,TEM-1,beta-lactamase_0,P62593,0.920809,NO,125,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.441,-2.752,1.311,,,H,A,0.48,-0.7,1.874,,63.29,HHP,-1.248,0.0500837,0.00383964,0.920809 beta-lactamase_2500_S221G,beta-lactamase_2500_221,TEM-1,beta-lactamase_2500,P62593,0.920821,NO,221,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.754,-3.136,1.382,,0.624,H,A,0.27,-0.2,1.971,,74.48,BPH,-1.59967,0.361275,0.0046094,0.920821 kka2_1:4_P128T,kka2_1:4_128,Kka2,kka2_1:4,P00552,0.920863,NO,128,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.922,-2.576,0.654,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.168804,0.00774689,0.920863 kka2_1:2_I254T,kka2_1:2_254,Kka2,kka2_1:2,P00552,0.920899,NO,254,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.933,-3.596,1.663,,0.135,H,A,1.52,-0.6,2.562,,71.59,BHH,-1.668,0.295029,0.0132375,0.920899 beta-lactamase_0_G90L,beta-lactamase_0_90,TEM-1,beta-lactamase_0,P62593,0.920939,NO,90,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-2.091,-3.689,1.598,,0.598,T,A,0.29,0.32,2.04,,77.62,HOB,-1.52633,0.0500837,0.00490273,0.920939 beta-lactamase_625_L120C,beta-lactamase_625_120,TEM-1,beta-lactamase_625,P62593,0.92095,NO,120,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.044,-4.81,3.766,,,H,A,0.55,-1.13,7.813,,64.69,AHO,-1.13633,0.213352,0.00143563,0.92095 PSD95pdz3_N381I,PSD95pdz3_381,PSD95pdz3,PSD95pdz3,P31016,0.920951,NO,381,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-1.41,-3.692,2.282,5.66057,,,,,28.2162,,,,BPH,-1.37767,0.0758425,0.000265374,0.920951 kka2_1:8_F48W,kka2_1:8_48,Kka2,kka2_1:8,P00552,0.920957,NO,48,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.453,-4.763,3.31,,0.296,E,B,1.62,-0.99,14.194,14.194,55.3,HHH,-1.444,0.100394,0.00475422,0.920957 kka2_1:8_F48W,kka2_1:8_48,Kka2,kka2_1:8,P00552,0.920957,NO,48,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.453,-4.763,3.31,,0.296,E,B,1.62,-0.99,14.194,14.194,55.3,HHH,-1.444,0.100394,0.00475422,0.920957 gb1_E241D,gb1_241,gb1,gb1,P06654,0.920989,NO,241,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.672,-2.957,1.285,,,,,,,0.344,,11.83,OAP,-1.27933,0.177985,0.00250604,0.920989 beta-lactamase_2500_M153Q,beta-lactamase_2500_153,TEM-1,beta-lactamase_2500,P62593,0.921015,NO,153,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-3.193,-4.202,1.009,,0.14,T,A,0.55,-0.11,3.409,,77.62,PHO,-2.25767,0.361275,0.00509109,0.921015 beta-lactamase_P253V,beta-lactamase_253,TEM-1,beta-lactamase,P62593,0.921033,NO,253,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-2.253,-3.658,1.405,5.24842,0.308,,B,0.73,-0.46,2.293,,73.08,BOP,-2.10633,0.221079,0.00786358,0.921033 kka2_1:1_G10V,kka2_1:1_10,Kka2,kka2_1:1,P00552,0.921053,NO,10,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.921,-3.683,1.762,,,,,,,1.862,,71.59,HOP,-2.10733,0.520039,0.00289233,0.921053 beta-lactamase_0_G141W,beta-lactamase_0_141,TEM-1,beta-lactamase_0,P62593,0.921115,NO,141,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.828,-5.233,4.405,,0.575,T,l,0.29,-0.28,0.722,,64.69,HOO,-1.08933,0.0500837,0.0012419,0.921115 PSD95pdz3_G344T,PSD95pdz3_344,PSD95pdz3,PSD95pdz3,P31016,0.92112,NO,344,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.008,-3.328,2.32,4.83855,,,,,14.06,,,,HOO,-1.10767,0.0758425,0.00078498,0.92112 beta-lactamase_625_E87N,beta-lactamase_625_87,TEM-1,beta-lactamase_625,P62593,0.921162,NO,87,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.421,-3.684,2.263,,0.048,,B,1.04,0.92,17.923,17.923,64.69,PAP,-1.969,0.213352,0.00337888,0.921162 beta-lactamase_2500_R92N,beta-lactamase_2500_92,TEM-1,beta-lactamase_2500,P62593,0.921164,NO,92,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.718,-2.988,1.27,,0.479,E,B,1.2,1.36,3.069,,65.38,BBH,-1.50367,0.361275,0.00429626,0.921164 beta-lactamase_0_V106K,beta-lactamase_0_106,TEM-1,beta-lactamase_0,P62593,0.921168,NO,106,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.218,-3.831,2.613,,0.258,T,A,0.44,0.24,0.952,,72.73,OHP,-1.04933,0.0500837,0.00304168,0.921168 beta-lactamase_39_K213E,beta-lactamase_39_213,TEM-1,beta-lactamase_39,P62593,0.921217,NO,213,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.81,-2.688,0.878,,0.67,,A,2.34,0.29,2.648,,67.83,ABH,-1.57767,0.0495842,0.00610411,0.921217 PSD95pdz3_F337R,PSD95pdz3_337,PSD95pdz3,PSD95pdz3,P31016,0.921269,NO,337,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.524,-3.84,2.316,5.22838,,,,,13.4936,,,,HHH,-1.59467,0.0758425,0.000875287,0.921269 beta-lactamase_2500_W163C,beta-lactamase_2500_163,TEM-1,beta-lactamase_2500,P62593,0.921274,NO,163,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-1.843,-5.117,3.274,,0.467,,B,0.47,-0.5,32.624,32.624,63.99,BHA,-1.269,0.361275,0.00418955,0.921274 E1_Ubiquitin_L73F,E1_Ubiquitin_73,Uba1,E1_Ubiquitin,P0CG63,0.921309,NO,73,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.039,-3.434,2.395,,0.518,,B,1.3,1,,,,BHB,-1.175,0.18783,0.00111236,0.921309 E1_Ubiquitin_Q41R,E1_Ubiquitin_41,Uba1,E1_Ubiquitin,P0CG63,0.921309,NO,41,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-1.25,-3.075,1.825,,0.017,E,B,,-0.98,,,,PPB,-1.344,0.18783,0.00215097,0.921309 E1_Ubiquitin_R42S,E1_Ubiquitin_42,Uba1,E1_Ubiquitin,P0CG63,0.921309,NO,42,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.302,-3.196,1.894,,0.244,E,B,,-0.54,,,,PBH,-1.24667,0.18783,0.00224033,0.921309 beta-lactamase_625_L38R,beta-lactamase_625_38,TEM-1,beta-lactamase_625,P62593,0.921344,NO,38,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.343,-4.054,2.711,,0.088,H,A,0.55,0.2,1.986,,64.34,PHO,-1.78033,0.213352,0.00373244,0.921344 kka2_1:4_R38C,kka2_1:4_38,Kka2,kka2_1:4,P00552,0.921384,NO,38,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.207,-4.996,3.789,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.168804,0.00372499,0.921384 beta-lactamase_0_K71A,beta-lactamase_0_71,TEM-1,beta-lactamase_0,P62593,0.921433,NO,71,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-0.8,-3.078,2.278,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.0500837,0.00103192,0.921433 beta-lactamase_0_L28G,beta-lactamase_0_28,TEM-1,beta-lactamase_0,P62593,0.921458,NO,28,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.579,-3.602,2.023,,0.277,H,A,0.55,-0.16,9.35,9.35,93.01,PHH,-2.11333,0.0500837,0.00359321,0.921458 kka2_1:8_R239L,kka2_1:8_239,Kka2,kka2_1:8,P00552,0.921459,NO,239,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.949,-2.571,-0.378,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.100394,0.00835326,0.921459 kka2_1:8_R239L,kka2_1:8_239,Kka2,kka2_1:8,P00552,0.921459,NO,239,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.949,-2.571,-0.378,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.100394,0.00835326,0.921459 kka2_1:8_V214T,kka2_1:8_214,Kka2,kka2_1:8,P00552,0.921542,NO,214,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.261,-3.47,2.209,,0.117,E,B,1.48,-0.31,1.859,,64.39,OHH,-0.941667,0.100394,0.00692782,0.921542 kka2_1:8_V214T,kka2_1:8_214,Kka2,kka2_1:8,P00552,0.921542,NO,214,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.261,-3.47,2.209,,0.117,E,B,1.48,-0.31,1.859,,64.39,OHH,-0.941667,0.100394,0.00692782,0.921542 beta-lactamase_0_V72S,beta-lactamase_0_72,TEM-1,beta-lactamase_0,P62593,0.92158,NO,72,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.658,-3.477,1.819,,,H,A,0.44,-1.03,2.964,,65.73,BHH,-1.32167,0.0500837,0.00501194,0.92158 kka2_1:4_R253C,kka2_1:4_253,Kka2,kka2_1:4,P00552,0.921581,NO,253,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.356,-3.227,1.871,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.168804,0.0144195,0.921581 beta-lactamase_0_L188E,beta-lactamase_0_188,TEM-1,beta-lactamase_0,P62593,0.921606,NO,188,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.166,-2.834,1.668,,,H,A,0.55,-0.3,2.739,,60.14,PHB,-1.47033,0.0500837,0.00295687,0.921606 beta-lactamase_0_L197S,beta-lactamase_0_197,TEM-1,beta-lactamase_0,P62593,0.921628,NO,197,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.853,-3.532,2.679,,0.007,S,B,0.55,0.33,1.087,,60.14,HHP,-1.833,0.0500837,0.00144602,0.921628 beta-lactamase_S57L,beta-lactamase_57,TEM-1,beta-lactamase,P62593,0.921637,NO,57,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.918,-2.848,0.93,5.64201,0.352,E,B,0.25,-0.18,1.971,,72.73,APH,-2.29167,0.221079,0.00492804,0.921637 kka2_1:2_A25L,kka2_1:2_25,Kka2,kka2_1:2,P00552,0.921653,NO,25,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.496,-3.561,1.065,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.295029,0.00595636,0.921653 Pab1_Y143C,Pab1_143,Pab1,Pab1,P04147,0.921707,NO,143,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-1.961,-4.912,2.951,,0.409,H,A,,0.3,,,,HHA,-1.39633,0.175299,0.00160364,0.921707 beta-lactamase_E46V,beta-lactamase_46,TEM-1,beta-lactamase,P62593,0.921751,NO,46,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.94,-1.834,-0.106,5.36461,0.021,E,B,1.51,0.14,0.373,,59.44,HAH,-2.079,0.221079,0.00427568,0.921751 beta-lactamase_0_R202F,beta-lactamase_0_202,TEM-1,beta-lactamase_0,P62593,0.921769,NO,202,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.292,-4.334,3.042,,0.188,H,A,1.2,0.62,7.016,,77.62,PBP,-1.54767,0.0500837,0.00321899,0.921769 kka2_1:8_N195D,kka2_1:8_195,Kka2,kka2_1:8,P00552,0.921771,NO,195,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-0.836,-2.379,1.543,,0.037,G,A,0.43,-1.36,1.108,,48.11,OPH,-1.26567,0.100394,0.00276134,0.921771 kka2_1:8_N195D,kka2_1:8_195,Kka2,kka2_1:8,P00552,0.921771,NO,195,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-0.836,-2.379,1.543,,0.037,G,A,0.43,-1.36,1.108,,48.11,OPH,-1.26567,0.100394,0.00276134,0.921771 gb1_T281N,gb1_281,gb1,gb1,P06654,0.921776,NO,281,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.828,-3.361,1.533,,,,,,,1.038,,35.71,HPA,-1.63667,0.177985,0.00284418,0.921776 beta-lactamase_0_L73Y,beta-lactamase_0_73,TEM-1,beta-lactamase_0,P62593,0.921785,NO,73,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.507,-3.917,2.41,,,H,A,0.55,-0.64,0.877,,67.83,HHH,-1.487,0.0500837,0.00488983,0.921785 beta-lactamase_0_L160I,beta-lactamase_0_160,TEM-1,beta-lactamase_0,P62593,0.921796,NO,160,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.977,-2.155,1.178,,0.022,,B,0.55,-0.6,0.68,,44.41,BHA,-0.936,0.0500837,0.00193775,0.921796 beta-lactamase_T147E,beta-lactamase_147,TEM-1,beta-lactamase,P62593,0.921826,NO,147,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.149,-3.519,2.37,5.37474,0.281,H,A,0.8,-0.68,2.838,,64.34,HPH,-1.456,0.221079,0.00226017,0.921826 PSD95pdz3_K355Y,PSD95pdz3_355,PSD95pdz3,PSD95pdz3,P31016,0.92183,NO,355,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.416,-3.844,2.428,5.56865,,,,,17.2556,,,,BBO,-1.33533,0.0758425,0.00063703,0.92183 beta-lactamase_V29R,beta-lactamase_29,TEM-1,beta-lactamase,P62593,0.921911,NO,29,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-2.856,-3.682,0.826,5.58481,0.733,H,A,0.23,-0.78,1.287,,93.01,HHB,-2.24733,0.221079,0.00318969,0.921911 kka2_1:8_I141F,kka2_1:8_141,Kka2,kka2_1:8,P00552,0.921917,NO,141,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.495,-3.83,2.335,,0.068,H,A,1.52,-0.01,2.144,,92.05,BHA,-1.689,0.100394,0.00744745,0.921917 kka2_1:8_I141F,kka2_1:8_141,Kka2,kka2_1:8,P00552,0.921917,NO,141,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.495,-3.83,2.335,,0.068,H,A,1.52,-0.01,2.144,,92.05,BHA,-1.689,0.100394,0.00744745,0.921917 kka2_1:4_M197Q,kka2_1:4_197,Kka2,kka2_1:4,P00552,0.921949,NO,197,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.707,-4.152,2.445,,0.121,E,B,0.55,-1.19,0.415,,65.53,HHH,-1.847,0.168804,0.00921295,0.921949 beta-lactamase_0_E26M,beta-lactamase_0_26,TEM-1,beta-lactamase_0,P62593,0.921988,NO,26,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.454,-4.568,2.114,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.0500837,0.00297948,0.921988 beta-lactamase_0_M66S,beta-lactamase_0_66,TEM-1,beta-lactamase_0,P62593,0.921994,NO,66,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.362,-3.571,2.209,,0.013,,A,0.55,-0.7,1.204,,73.08,OHH,-1.49567,0.0500837,0.00412876,0.921994 beta-lactamase_0_L199N,beta-lactamase_0_199,TEM-1,beta-lactamase_0,P62593,0.922,NO,199,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-2.942,-3.124,0.182,,0.832,H,A,0.55,0.42,10.85,10.85,77.62,PHH,-2.32933,0.0500837,0.0048649,0.922 beta-lactamase_156_L223Y,beta-lactamase_156_223,TEM-1,beta-lactamase_156,P62593,0.922028,NO,223,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.055,-3.889,2.834,,0.27,,B,0.55,0.09,1.511,,74.48,HHO,-1.35033,0.111618,0.00372793,0.922028 gb1_K239Y,gb1_239,gb1,gb1,P06654,0.922037,NO,239,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-3.043,-3.973,0.93,,,,,,,1.326,,45.54,HBO,-2.31467,0.177985,0.00207004,0.922037 gb1_Y229C,gb1_229,gb1,gb1,P06654,0.922037,NO,229,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-1.282,-4.598,3.316,,,,,,,,,,PHB,-1.4915,0.177985,0.00366605,0.922037 PSD95pdz3_F340N,PSD95pdz3_340,PSD95pdz3,PSD95pdz3,P31016,0.922098,NO,340,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.524,-3.805,2.281,5.79283,,,,,11.8045,,,,PHH,-1.55767,0.0758425,0.000836987,0.922098 beta-lactamase_G234S,beta-lactamase_234,TEM-1,beta-lactamase,P62593,0.922124,NO,234,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.62,-3.161,2.541,4.24221,0.023,E,B,0.46,-0.86,,,,POH,-1.25733,0.221079,0.000889577,0.922124 beta-lactamase_0_G234Y,beta-lactamase_0_234,TEM-1,beta-lactamase_0,P62593,0.922149,NO,234,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.62,-4.387,3.767,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.0500837,0.000889577,0.922149 kka2_1:1_A108P,kka2_1:1_108,Kka2,kka2_1:1,P00552,0.922166,NO,108,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.061,-2.19,0.129,,0.243,.,B,0.46,-1.34,3.156,,71.59,HHO,-1.57033,0.520039,0.00751209,0.922166 beta-lactamase_2500_F149L,beta-lactamase_2500_149,TEM-1,beta-lactamase_2500,P62593,0.922174,NO,149,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.299,-3.137,1.838,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.361275,0.00418462,0.922174 beta-lactamase_0_N173P,beta-lactamase_0_173,TEM-1,beta-lactamase_0,P62593,0.9222,NO,173,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-2.663,-3.891,1.228,,1.044,T,l,0.61,1.25,1.133,,77.62,OPA,-1.46633,0.0500837,0.0033769,0.9222 beta-lactamase_2500_I229C,beta-lactamase_2500_229,TEM-1,beta-lactamase_2500,P62593,0.922203,NO,229,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.267,-4.722,3.455,,0.083,E,B,0.48,-0.76,3.875,,50,HHH,-1.58767,0.361275,0.00477249,0.922203 beta-lactamase_0_R159V,beta-lactamase_0_159,TEM-1,beta-lactamase_0,P62593,0.922236,NO,159,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-0.94,-3.779,2.839,,0.316,,B,1.2,-0.55,1.426,,64.34,PBH,-1.011,0.0500837,0.00108472,0.922236 beta-lactamase_Q4L,beta-lactamase_4,TEM-1,beta-lactamase,P62593,0.92224,NO,4,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,,-3.272,0.708,,,,,,,,,,HPB,,0.221079,0.00316562,0.92224 beta-lactamase_2500_E108F,beta-lactamase_2500_108,TEM-1,beta-lactamase_2500,P62593,0.922253,NO,108,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.46,-4.416,2.956,,0.572,G,A,1.04,1.87,1.147,,72.73,PAB,-1.437,0.361275,0.00413372,0.922253 beta-lactamase_0_L146H,beta-lactamase_0_146,TEM-1,beta-lactamase_0,P62593,0.92228,NO,146,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.462,-4.92,3.458,,0.007,H,A,0.55,-0.56,2.051,,64.69,AHP,-1.656,0.0500837,0.00474542,0.92228 beta-lactamase_L38Y,beta-lactamase_38,TEM-1,beta-lactamase,P62593,0.922286,NO,38,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.343,-2.956,1.613,5.23728,0.088,H,A,1.75,0.2,1.986,,64.34,PHO,-1.78033,0.221079,0.00373244,0.922286 kka2_1:8_M178I,kka2_1:8_178,Kka2,kka2_1:8,P00552,0.922292,NO,178,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-3.206,-2.948,-0.258,,0.554,,b,1.59,0.68,13.268,13.268,71.59,BHO,-2.154,0.100394,0.00717253,0.922292 kka2_1:8_M178I,kka2_1:8_178,Kka2,kka2_1:8,P00552,0.922292,NO,178,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-3.206,-2.948,-0.258,,0.554,,b,1.59,0.68,13.268,13.268,71.59,BHO,-2.154,0.100394,0.00717253,0.922292 beta-lactamase_0_L120H,beta-lactamase_0_120,TEM-1,beta-lactamase_0,P62593,0.9223,NO,120,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.044,-3.066,2.022,,,H,A,0.55,-1.13,1.2,,64.69,AHO,-1.13633,0.0500837,0.00143563,0.9223 beta-lactamase_625_S266H,beta-lactamase_625_266,TEM-1,beta-lactamase_625,P62593,0.922301,NO,266,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.213352,0.0140785,0.922301 beta-lactamase_0_P172N,beta-lactamase_0_172,TEM-1,beta-lactamase_0,P62593,0.922303,NO,172,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.998,-3.875,2.877,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.0500837,0.00312594,0.922303 kka2_1:4_L241I,kka2_1:4_241,Kka2,kka2_1:4,P00552,0.922309,NO,241,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.158,-3.164,2.006,,0.08,H,A,0.55,-0.82,1.598,,63.26,HHH,-1.58533,0.168804,0.0117299,0.922309 beta-lactamase_0_L38P,beta-lactamase_0_38,TEM-1,beta-lactamase_0,P62593,0.922329,NO,38,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.343,-2.934,1.591,,0.088,H,A,0.55,0.2,13.556,13.556,64.34,PHO,-1.78033,0.0500837,0.00373244,0.922329 beta-lactamase_2500_C75V,beta-lactamase_2500_75,TEM-1,beta-lactamase_2500,P62593,0.922384,NO,75,C,V,CV,Special,Hydrophobic,5.07,5.60847,0.538465,192,121,117,-4,108.5,140,31.5,-1.245,-3.383,2.138,,,H,A,0.46,-0.87,0.844,,50,HOO,-1.24333,0.361275,0.0034616,0.922384 beta-lactamase_156_R59L,beta-lactamase_156_59,TEM-1,beta-lactamase_156,P62593,0.922388,NO,59,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.345,-3.484,2.139,,0.329,S,L,1.2,-0.09,2.995,,73.08,HBO,-2.24267,0.111618,0.00318082,0.922388 kka2_1:4_P45H,kka2_1:4_45,Kka2,kka2_1:4,P00552,0.922398,NO,45,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.774,-4.807,3.033,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.168804,0.00590481,0.922398 beta-lactamase_2500_D33W,beta-lactamase_2500_33,TEM-1,beta-lactamase_2500,P62593,0.922409,NO,33,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.321,-5.495,3.174,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.361275,0.00435556,0.922409 beta-lactamase_39_D231F,beta-lactamase_39_231,TEM-1,beta-lactamase_39,P62593,0.922429,NO,231,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.816,-4.318,3.502,,,E,B,0.75,-1.06,0.462,,65.38,HAB,-0.994,0.0495842,0.00107395,0.922429 beta-lactamase_0_I277F,beta-lactamase_0_277,TEM-1,beta-lactamase_0,P62593,0.922432,NO,277,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.0500837,0.0169305,0.922432 beta-lactamase_A9R,beta-lactamase_9,TEM-1,beta-lactamase,P62593,0.922438,NO,9,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.147,-3.982,1.835,,,,,,,5.128,,72.73,HHH,-2.04267,0.221079,0.00247263,0.922438 beta-lactamase_0_R162K,beta-lactamase_0_162,TEM-1,beta-lactamase_0,P62593,0.922466,NO,162,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.016,-2.948,1.932,,0.124,S,B,1.2,-0.37,1.026,,64.69,ABH,-1.25,0.0500837,0.000561334,0.922466 kka2_1:8_R173P,kka2_1:8_173,Kka2,kka2_1:8,P00552,0.92248,NO,173,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.407,-4.037,1.63,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.100394,0.00784999,0.92248 kka2_1:8_R173P,kka2_1:8_173,Kka2,kka2_1:8,P00552,0.92248,NO,173,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.407,-4.037,1.63,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.100394,0.00784999,0.92248 beta-lactamase_0_V157T,beta-lactamase_0_157,TEM-1,beta-lactamase_0,P62593,0.922544,NO,157,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.751,-2.302,0.551,,0.308,S,a,0.44,-0.75,3.106,,69.58,BHP,-2.00767,0.0500837,0.00506849,0.922544 kka2_1:2_L7D,kka2_1:2_7,Kka2,kka2_1:2,P00552,0.922544,NO,7,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.926,-2.297,0.371,,,,,,,3.012,,71.59,OHB,-2.12333,0.295029,0.00269456,0.922544 PSD95pdz3_D332A,PSD95pdz3_332,PSD95pdz3,PSD95pdz3,P31016,0.922547,NO,332,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.264,-2.984,1.72,6.09878,,,,,48.762,,,,AAO,-1.22533,0.0758425,0.000937818,0.922547 beta-lactamase_M66F,beta-lactamase_66,TEM-1,beta-lactamase,P62593,0.922555,NO,66,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.362,-3.731,2.369,5.29561,0.013,,A,1.3,-0.7,1.319,,73.08,OHH,-1.49567,0.221079,0.00412876,0.922555 gb1_T281E,gb1_281,gb1,gb1,P06654,0.922559,NO,281,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.828,-3.222,1.394,,,,,,,1.038,,35.71,HPA,-1.63667,0.177985,0.00284418,0.922559 beta-lactamase_0_T69M,beta-lactamase_0_69,TEM-1,beta-lactamase_0,P62593,0.922571,NO,69,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-0.973,-4.54,3.567,,,G,A,0.22,-1.24,0.505,,93.01,PPH,-1.01833,0.0500837,0.00127498,0.922571 beta-lactamase_2500_K144W,beta-lactamase_2500_144,TEM-1,beta-lactamase_2500,P62593,0.922597,NO,144,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-2.388,-5.522,3.134,,0.863,H,A,2.34,1.27,0.515,,77.62,OBA,-1.904,0.361275,0.00481141,0.922597 beta-lactamase_0_F58Y,beta-lactamase_0_58,TEM-1,beta-lactamase_0,P62593,0.922614,NO,58,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-2.914,-1.89,-1.024,,0.266,E,B,0.58,-0.07,24.637,24.637,77.62,PHB,-2.059,0.0500837,0.00523369,0.922614 beta-lactamase_0_W163A,beta-lactamase_0_163,TEM-1,beta-lactamase_0,P62593,0.922615,NO,163,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-1.843,-3.41,1.567,,0.467,,B,0.47,-0.5,13.843,13.843,63.99,BHA,-1.269,0.0500837,0.00418955,0.922615 beta-lactamase_2500_M153N,beta-lactamase_2500_153,TEM-1,beta-lactamase_2500,P62593,0.922626,NO,153,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-3.193,-3.994,0.801,,0.14,T,A,0.55,-0.11,3.409,,77.62,PHO,-2.25767,0.361275,0.00509109,0.922626 beta-lactamase_0_R220C,beta-lactamase_0_220,TEM-1,beta-lactamase_0,P62593,0.922662,NO,220,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-0.942,-5.009,4.067,,0.295,I,A,1.2,-0.76,21.573,21.573,74.48,HBP,-1.33633,0.0500837,0.00232421,0.922662 beta-lactamase_I140I,beta-lactamase_140,TEM-1,beta-lactamase,P62593,0.922666,NO,140,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.733,-1.733,,5.29918,0.128,H,A,1,0.41,1.16,,73.08,PHO,-1.48733,0.221079,0.00597777,0.922666 kka2_1:1_D159T,kka2_1:1_159,Kka2,kka2_1:1,P00552,0.922666,NO,159,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.82,-3.513,2.693,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.520039,0.0030485,0.922666 beta-lactamase_2500_K286V,beta-lactamase_2500_286,TEM-1,beta-lactamase_2500,P62593,0.922668,NO,286,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.361275,,0.922668 Pab1_N132L,Pab1_132,Pab1,Pab1,P04147,0.922679,NO,132,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-1.079,-3.4,2.321,,0.412,S,l,,0.9,,,,BPH,-1.067,0.175299,0.000347671,0.922679 kka2_1:8_L103N,kka2_1:8_103,Kka2,kka2_1:8,P00552,0.922688,NO,103,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-2.362,-3.939,1.577,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.100394,0.00574792,0.922688 kka2_1:8_L103N,kka2_1:8_103,Kka2,kka2_1:8,P00552,0.922688,NO,103,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-2.362,-3.939,1.577,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.100394,0.00574792,0.922688 beta-lactamase_0_P65G,beta-lactamase_0_65,TEM-1,beta-lactamase_0,P62593,0.922722,NO,65,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.894,-3.443,2.549,,0.098,E,B,0.52,-0.62,0.663,,40.56,HOH,-1.03233,0.0500837,0.00152776,0.922722 beta-lactamase_0_I258H,beta-lactamase_0_258,TEM-1,beta-lactamase_0,P62593,0.922731,NO,258,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.0500837,0.007931,0.922731 beta-lactamase_A34Q,beta-lactamase_34,TEM-1,beta-lactamase,P62593,0.922757,NO,34,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.059,-4.16,2.101,4.9129,,H,A,0.75,-0.54,3.614,,73.78,AHA,-1.74967,0.221079,0.00407913,0.922757 beta-lactamase_156_L218S,beta-lactamase_156_218,TEM-1,beta-lactamase_156,P62593,0.922778,NO,218,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.391,-2.79,1.399,,,I,b,0.55,-0.53,17.202,17.202,74.48,OHH,-1.58867,0.111618,0.00618274,0.922778 gb1_G264W,gb1_264,gb1,gb1,P06654,0.922819,NO,264,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.833,-5.215,3.382,,,,,,,0.864,,44.87,POH,-1.61267,0.177985,0.0049716,0.922819 beta-lactamase_625_L218I,beta-lactamase_625_218,TEM-1,beta-lactamase_625,P62593,0.922828,NO,218,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.391,-3.447,2.056,,,I,b,0.55,-0.53,17.202,17.202,74.48,OHH,-1.58867,0.213352,0.00618274,0.922828 beta-lactamase_A222D,beta-lactamase_222,TEM-1,beta-lactamase,P62593,0.922852,NO,222,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.103,-3.723,1.62,5.2262,0.233,H,A,0.47,-0.25,0.379,,77.62,PHH,-1.63733,0.221079,0.00466094,0.922852 beta-lactamase_0_S80F,beta-lactamase_0_80,TEM-1,beta-lactamase_0,P62593,0.922856,NO,80,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.029,-4.287,2.258,,0.192,H,A,0.27,0.46,12.403,12.403,77.62,HPB,-1.44567,0.0500837,0.00565569,0.922856 kka2_1:1_E160Q,kka2_1:1_160,Kka2,kka2_1:1,P00552,0.922882,NO,160,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.683,-3.734,2.051,,0.989,G,A,1.04,2.28,0.273,,71.59,AAA,-1.36133,0.520039,0.00935762,0.922882 beta-lactamase_0_E26V,beta-lactamase_0_26,TEM-1,beta-lactamase_0,P62593,0.922928,NO,26,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.454,-2.776,0.322,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.0500837,0.00297948,0.922928 beta-lactamase_H285V,beta-lactamase_285,TEM-1,beta-lactamase,P62593,0.922936,NO,285,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-1.845,-3.53,1.685,5.64289,0.312,T,a,0.35,0.64,1.401,,72.73,BBH,-1.64567,0.221079,0.101555,0.922936 kka2_1:8_V214F,kka2_1:8_214,Kka2,kka2_1:8,P00552,0.922937,NO,214,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.261,-3.945,2.684,,0.117,E,B,1.48,-0.31,1.859,,64.39,OHH,-0.941667,0.100394,0.00692782,0.922937 kka2_1:8_V214F,kka2_1:8_214,Kka2,kka2_1:8,P00552,0.922937,NO,214,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.261,-3.945,2.684,,0.117,E,B,1.48,-0.31,1.859,,64.39,OHH,-0.941667,0.100394,0.00692782,0.922937 beta-lactamase_625_G114F,beta-lactamase_625_114,TEM-1,beta-lactamase_625,P62593,0.922959,NO,114,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.094,-4.331,3.237,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.213352,0.00224919,0.922959 beta-lactamase_0_E272N,beta-lactamase_0_272,TEM-1,beta-lactamase_0,P62593,0.922995,NO,272,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.127,-2.497,1.37,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.0500837,0.00545371,0.922995 beta-lactamase_X287R,beta-lactamase_287,TEM-1,beta-lactamase,P62593,0.923002,NO,287,X,R,XR,Stop,PositiveCharge,5.71,6.34148,0.631478,,132.5,174,41,141.9,173.4,31.5,,,,,,,,,,,,,HXO,-1.111,0.221079,,0.923002 WW_domain_T196C,WW_domain_196,Yap65,WW_domain,P46937,0.923015,NO,196,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.782,-4.789,3.007,5.5744,,,,,,5.836,,70.04,PPP,-1.732,0.153962,0.00421377,0.923015 E1_Ubiquitin_Q40F,E1_Ubiquitin_40,Uba1,E1_Ubiquitin,P0CG63,0.923077,NO,40,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-1.48,-4.099,2.619,,0.387,G,A,,0.03,,,,OPP,-1.365,0.18783,0.0037961,0.923077 E1_Ubiquitin_T68M,E1_Ubiquitin_68,Uba1,E1_Ubiquitin,P0CG63,0.923077,NO,68,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,,,,,,,,,,,,,OPH,-1.039,0.18783,0.00314321,0.923077 gb1_G264L,gb1_264,gb1,gb1,P06654,0.923079,NO,264,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.833,-2.227,0.394,,,,,,,0.864,,44.87,POH,-1.61267,0.177985,0.0049716,0.923079 PSD95pdz3_G356N,PSD95pdz3_356,PSD95pdz3,PSD95pdz3,P31016,0.923083,NO,356,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.008,-3.13,2.122,4.8656,,,,,11.9575,,,,BOA,-1.22933,0.0758425,0.000623061,0.923083 beta-lactamase_156_W208S,beta-lactamase_156_208,TEM-1,beta-lactamase_156,P62593,0.923107,NO,208,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-0.818,-3.836,3.018,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.111618,0.00126609,0.923107 beta-lactamase_0_A235I,beta-lactamase_0_235,TEM-1,beta-lactamase_0,P62593,0.92318,NO,235,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.266,-3.683,2.417,,0.32,E,B,0.46,-0.86,2.261,,50,OHO,-0.89,0.0500837,0.00493474,0.92318 PSD95pdz3_N326D,PSD95pdz3_326,PSD95pdz3,PSD95pdz3,P31016,0.923195,NO,326,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-1.41,-2.7,1.29,5.52537,,,,,19.0688,,,,HPH,-1.52133,0.0758425,0.00101078,0.923195 hsp90_N588M,hsp90_588,hsp90,hsp90,P02829,0.923204,NO,588,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-3.051,-3.858,0,4.61142,0.019,H,A,0.14,0.39,,,,HPH,-3.12167,0.368192,0.000222939,0.923204 beta-lactamase_2500_A247S,beta-lactamase_2500_247,TEM-1,beta-lactamase_2500,P62593,0.923242,NO,247,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.361275,0.00611275,0.923242 beta-lactamase_0_M67E,beta-lactamase_0_67,TEM-1,beta-lactamase_0,P62593,0.923292,NO,67,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-2.231,-3.761,1.53,,0.006,G,P,0.55,-0.81,24.165,24.165,65.03,HHP,-1.502,0.0500837,0.00409753,0.923292 beta-lactamase_D250P,beta-lactamase_250,TEM-1,beta-lactamase,P62593,0.923305,NO,250,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.335,-1.83,-0.505,5.72026,0.89,T,L,0.23,1.53,24.737,24.737,66.08,OAO,-1.85133,0.221079,0.00550899,0.923305 kka2_1:8_G210Q,kka2_1:8_210,Kka2,kka2_1:8,P00552,0.923331,NO,210,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.095,-4.139,3.044,,0.103,T,A,0.75,-0.62,2.687,,50,OOB,-0.966667,0.100394,0.00598378,0.923331 kka2_1:8_G210Q,kka2_1:8_210,Kka2,kka2_1:8,P00552,0.923331,NO,210,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.095,-4.139,3.044,,0.103,T,A,0.75,-0.62,2.687,,50,OOB,-0.966667,0.100394,0.00598378,0.923331 Pab1_H172Q,Pab1_172,Pab1,Pab1,P04147,0.923355,NO,172,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-1.21,-3.491,2.281,,0.076,E,B,0.35,-0.87,,,,HBH,-1.26667,0.175299,0.000296642,0.923355 beta-lactamase_A183R,beta-lactamase_183,TEM-1,beta-lactamase,P62593,0.923359,NO,183,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.231,-3.825,2.594,4.84712,0.155,H,A,0.55,-0.91,12.189,,77.62,HHH,-1.53367,0.221079,0.00296631,0.923359 beta-lactamase_39_T139W,beta-lactamase_39_139,TEM-1,beta-lactamase_39,P62593,0.923386,NO,139,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.901,-5.432,3.531,,0.216,H,A,0.22,0.39,0.421,,77.62,PPH,-2.04667,0.0495842,0.00441837,0.923386 beta-lactamase_L150A,beta-lactamase_150,TEM-1,beta-lactamase,P62593,0.923437,NO,150,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.326,-2.051,0.725,5.15566,,H,A,1.75,-0.2,1.615,,62.94,HHB,-1.86167,0.221079,0.00463171,0.923437 beta-lactamase_0_L167V,beta-lactamase_0_167,TEM-1,beta-lactamase_0,P62593,0.923451,NO,167,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.138,-2.277,1.139,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.0500837,0.00303566,0.923451 beta-lactamase_625_V259M,beta-lactamase_625_259,TEM-1,beta-lactamase_625,P62593,0.923493,NO,259,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.213352,0.0070773,0.923493 beta-lactamase_2500_S57F,beta-lactamase_2500_57,TEM-1,beta-lactamase_2500,P62593,0.923533,NO,57,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.918,-4.274,2.356,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.361275,0.00492804,0.923533 kka2_1:8_A172W,kka2_1:8_172,Kka2,kka2_1:8,P00552,0.92358,NO,172,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.757,-5.588,3.831,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.100394,0.0079265,0.92358 kka2_1:8_A172W,kka2_1:8_172,Kka2,kka2_1:8,P00552,0.92358,NO,172,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.757,-5.588,3.831,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.100394,0.0079265,0.92358 gb1_T281M,gb1_281,gb1,gb1,P06654,0.923597,NO,281,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.828,-4.368,2.54,,,,,,,1.038,,35.71,HPA,-1.63667,0.177985,0.00284418,0.923597 beta-lactamase_H285A,beta-lactamase_285,TEM-1,beta-lactamase,P62593,0.923634,NO,285,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-1.845,-3.243,1.398,5.64289,0.312,T,a,0.35,0.64,1.401,,72.73,BBH,-1.64567,0.221079,0.101555,0.923634 kka2_1:4_E142V,kka2_1:4_142,Kka2,kka2_1:4,P00552,0.92367,NO,142,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.221,-3.677,1.456,,0.471,H,A,1.52,0.85,3.693,,65.53,HAB,-2.08033,0.168804,0.00748883,0.92367 beta-lactamase_0_Q204R,beta-lactamase_0_204,TEM-1,beta-lactamase_0,P62593,0.923678,NO,204,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-1.382,-2.322,0.94,,0.204,H,A,0.64,0.09,2.646,,66.08,PPH,-1.49067,0.0500837,0.00364106,0.923678 beta-lactamase_H5E,beta-lactamase_5,TEM-1,beta-lactamase,P62593,0.923688,NO,5,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-2.698,-3.559,0.861,,,,,,,1.865,,72.73,PBH,-2.36967,0.221079,0.00292712,0.923688 beta-lactamase_I244C,beta-lactamase_244,TEM-1,beta-lactamase,P62593,0.923715,NO,244,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.555,-4.712,3.157,5.35885,,E,B,0.01,-0.84,0.379,,77.62,HHH,-1.385,0.221079,0.00605379,0.923715 kka2_1:1_A129S,kka2_1:1_129,Kka2,kka2_1:1,P00552,0.923741,NO,129,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.656,-2.58,0.924,,0.845,G,A,0.46,0.72,19.686,19.686,92.05,OHP,-1.99,0.520039,0.00726862,0.923741 beta-lactamase_T198R,beta-lactamase_198,TEM-1,beta-lactamase,P62593,0.923751,NO,198,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.168,-3.752,1.584,4.9209,0.489,,B,0.69,-0.13,0.37,,73.78,HPH,-1.98767,0.221079,0.004311,0.923751 Pab1_D136R,Pab1_136,Pab1,Pab1,P04147,0.923841,NO,136,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.602,-3.809,2.207,,,,,,,,,,OAH,-1.42367,0.175299,0.00227029,0.923841 beta-lactamase_2500_D99N,beta-lactamase_2500_99,TEM-1,beta-lactamase_2500,P62593,0.923843,NO,99,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.191,-3.466,2.275,,0.402,G,A,0.75,0.36,1.318,,64.69,PAH,-1.794,0.361275,0.00305446,0.923843 beta-lactamase_0_Q276N,beta-lactamase_0_276,TEM-1,beta-lactamase_0,P62593,0.923851,NO,276,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.0500837,0.0191712,0.923851 beta-lactamase_0_A200Y,beta-lactamase_0_200,TEM-1,beta-lactamase_0,P62593,0.923854,NO,200,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.878,-4.399,2.521,,0.757,H,A,0.46,-0.19,16.368,16.368,77.62,HHP,-2.001,0.0500837,0.0060056,0.923854 kka2_1:4_G201D,kka2_1:4_201,Kka2,kka2_1:4,P00552,0.923855,NO,201,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.56,-2.294,0.734,,0.149,T,l,0.29,-0.57,0.284,,52.65,POB,-1.92233,0.168804,0.00820117,0.923855 hsp90_W585I,hsp90_585,hsp90,hsp90,P02829,0.923879,NO,585,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-4.251,-2.939,0,5.31455,0.508,,B,1.22,0.43,,,,OHP,-3.17533,0.368192,0.000222939,0.923879 kka2_1:4_H139T,kka2_1:4_139,Kka2,kka2_1:4,P00552,0.923889,NO,139,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-2.809,-2.706,-0.103,,0.471,H,A,0.17,0.68,12.761,12.761,63.64,BBB,-2.22,0.168804,0.00734779,0.923889 beta-lactamase_156_Q204P,beta-lactamase_156_204,TEM-1,beta-lactamase_156,P62593,0.923898,NO,204,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-1.382,-3.857,2.475,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.111618,0.00364106,0.923898 beta-lactamase_0_D231V,beta-lactamase_0_231,TEM-1,beta-lactamase_0,P62593,0.923913,NO,231,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.816,-3.751,2.935,,,E,B,0.75,-1.06,4.975,,65.38,HAB,-0.994,0.0500837,0.00107395,0.923913 Pab1_E195F,Pab1_195,Pab1,Pab1,P04147,0.923938,NO,195,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.2,-4.162,2.962,,,,,,,,,,PAH,-1.72467,0.175299,0.000620107,0.923938 kka2_1:8_G245D,kka2_1:8_245,Kka2,kka2_1:8,P00552,0.923953,NO,245,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.812,-3.456,2.644,,0.655,T,g,0.75,0.03,1.148,,65.53,HOH,-1.19833,0.100394,0.00683899,0.923953 kka2_1:8_G245D,kka2_1:8_245,Kka2,kka2_1:8,P00552,0.923953,NO,245,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.812,-3.456,2.644,,0.655,T,g,0.75,0.03,1.148,,65.53,HOH,-1.19833,0.100394,0.00683899,0.923953 kka2_1:8_P128T,kka2_1:8_128,Kka2,kka2_1:8,P00552,0.923953,NO,128,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.922,-2.576,0.654,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.100394,0.00774689,0.923953 kka2_1:8_P128T,kka2_1:8_128,Kka2,kka2_1:8,P00552,0.923953,NO,128,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.922,-2.576,0.654,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.100394,0.00774689,0.923953 beta-lactamase_156_V78W,beta-lactamase_156_78,TEM-1,beta-lactamase_156,P62593,0.923968,NO,78,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.459,-5.345,3.886,,,H,A,0.44,-0.47,1.132,,63.64,HHH,-1.17833,0.111618,0.00492501,0.923968 PSD95pdz3_F325L,PSD95pdz3_325,PSD95pdz3,PSD95pdz3,P31016,0.924042,NO,325,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.524,-2.59,1.066,5.50654,,,,,12.7236,,,,OHP,-1.314,0.0758425,0.00102273,0.924042 beta-lactamase_156_W208T,beta-lactamase_156_208,TEM-1,beta-lactamase_156,P62593,0.924044,NO,208,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-0.818,-3.646,2.828,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.111618,0.00126609,0.924044 beta-lactamase_0_H24Y,beta-lactamase_0_24,TEM-1,beta-lactamase_0,P62593,0.924132,NO,24,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-2.481,-4.052,1.571,,,,,,,2.708,,93.01,OBO,-2.0035,0.0500837,0.00238894,0.924132 beta-lactamase_0_R242N,beta-lactamase_0_242,TEM-1,beta-lactamase_0,P62593,0.924135,NO,242,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.0500837,0.00452879,0.924135 hsp90_M589V,hsp90_589,hsp90,hsp90,P02829,0.924153,NO,589,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-3.858,-2.682,0,4.72723,0.032,H,A,0.84,0.31,,,,PHA,-3.24233,0.368192,0.000222939,0.924153 beta-lactamase_0_Y95W,beta-lactamase_0_95,TEM-1,beta-lactamase_0,P62593,0.924178,NO,95,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-1.715,-3.22,1.505,,0.122,,b,0.21,-0.37,2.914,,77.62,BHP,-2.16167,0.0500837,0.00479449,0.924178 beta-lactamase_A123S,beta-lactamase_123,TEM-1,beta-lactamase,P62593,0.924189,NO,123,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.834,-3.019,2.185,4.70061,0.039,H,A,0.52,-0.72,0.705,,41.26,PHH,-1.47367,0.221079,0.0010157,0.924189 beta-lactamase_I283C,beta-lactamase_283,TEM-1,beta-lactamase,P62593,0.924189,NO,283,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.638,-4.728,3.09,5.4178,0.165,H,A,1.23,0.04,1.576,,69.23,HHB,-1.735,0.221079,0.0429138,0.924189 beta-lactamase_K190W,beta-lactamase_190,TEM-1,beta-lactamase,P62593,0.924189,NO,190,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.994,-5.522,3.528,5.49163,0.371,H,A,1.82,0.16,29.753,29.753,77.62,BBH,-1.64167,0.221079,0.00574527,0.924189 beta-lactamase_S264A,beta-lactamase_264,TEM-1,beta-lactamase,P62593,0.924189,NO,264,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.985,-2.297,0.312,4.67475,0.04,,B,0.25,0.29,34.251,34.251,73.78,OPP,-2.19867,0.221079,0.0119399,0.924189 beta-lactamase_W163H,beta-lactamase_163,TEM-1,beta-lactamase,P62593,0.924189,NO,163,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-1.843,-3.378,1.535,6.2765,0.467,,B,1.22,-0.5,3.642,,63.99,BHA,-1.269,0.221079,0.00418955,0.924189 beta-lactamase_39_S241P,beta-lactamase_39_241,TEM-1,beta-lactamase_39,P62593,0.924192,NO,241,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.0495842,0.00452736,0.924192 Pab1_G163T,Pab1_163,Pab1,Pab1,P04147,0.924224,NO,163,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.809,-3.464,2.655,,0.356,B,g,,0.55,,,,POB,-1.80667,0.175299,0.00030953,0.924224 beta-lactamase_L188C,beta-lactamase_188,TEM-1,beta-lactamase,P62593,0.924294,NO,188,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.166,-4.777,3.611,5.55434,,H,A,1.07,-0.3,1.574,,60.14,PHB,-1.47033,0.221079,0.00295687,0.924294 beta-lactamase_2500_N173V,beta-lactamase_2500_173,TEM-1,beta-lactamase_2500,P62593,0.924301,NO,173,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-2.663,-3.738,1.075,,1.044,T,l,0.61,1.25,1.88,,77.62,OPA,-1.46633,0.361275,0.0033769,0.924301 beta-lactamase_156_A123L,beta-lactamase_156_123,TEM-1,beta-lactamase_156,P62593,0.924312,NO,123,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.834,-3.096,2.262,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.111618,0.0010157,0.924312 beta-lactamase_P172F,beta-lactamase_172,TEM-1,beta-lactamase,P62593,0.924339,NO,172,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.998,-4.371,3.373,5.98941,0.639,T,b,1.1,0.24,2.087,,74.48,HOP,-2.03067,0.221079,0.00312594,0.924339 kka2_1:8_L103P,kka2_1:8_103,Kka2,kka2_1:8,P00552,0.924367,NO,103,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-2.362,-3.937,1.575,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.100394,0.00574792,0.924367 kka2_1:8_L103P,kka2_1:8_103,Kka2,kka2_1:8,P00552,0.924367,NO,103,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-2.362,-3.937,1.575,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.100394,0.00574792,0.924367 kka2_1:1_G234A,kka2_1:1_234,Kka2,kka2_1:1,P00552,0.924376,NO,234,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-2.9,-2.255,-0.645,,0.494,H,A,0.29,-0.29,1.753,,71.59,OOA,-1.86767,0.520039,0.00984449,0.924376 beta-lactamase_0_A124R,beta-lactamase_0_124,TEM-1,beta-lactamase_0,P62593,0.924383,NO,124,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.181,-3.827,2.646,,,H,A,0.46,-0.9,1.876,,64.34,HHH,-1.152,0.0500837,0.00481399,0.924383 beta-lactamase_2500_L111S,beta-lactamase_2500_111,TEM-1,beta-lactamase_2500,P62593,0.924385,NO,111,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.76,-3.564,1.804,,0.328,T,A,0.55,0.93,1.966,,64.34,BHP,-1.884,0.361275,0.00480671,0.924385 beta-lactamase_M127C,beta-lactamase_127,TEM-1,beta-lactamase,P62593,0.924436,NO,127,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-2.251,-5.009,2.758,5.40552,0.312,S,A,1.07,0.32,1.671,,72.73,PHP,-1.40433,0.221079,0.00437927,0.924436 kka2_1:2_L259M,kka2_1:2_259,Kka2,kka2_1:2,P00552,0.924495,NO,259,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.088,-2.71,1.622,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.295029,0.0206964,0.924495 beta-lactamase_D99T,beta-lactamase_99,TEM-1,beta-lactamase,P62593,0.924502,NO,99,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.191,-3.531,2.34,5.66081,0.402,G,A,0.23,0.36,1.318,,64.69,PAH,-1.794,0.221079,0.00305446,0.924502 beta-lactamase_P253G,beta-lactamase_253,TEM-1,beta-lactamase,P62593,0.924533,NO,253,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-2.253,-2.791,0.538,5.24842,0.308,,B,0.73,-0.46,2.293,,73.08,BOP,-2.10633,0.221079,0.00786358,0.924533 kka2_1:8_L212V,kka2_1:8_212,Kka2,kka2_1:8,P00552,0.924553,NO,212,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.904,-2.413,1.509,,,,B,1.59,-0.78,1.708,,42.42,BHO,-0.799667,0.100394,0.0031426,0.924553 kka2_1:8_L212V,kka2_1:8_212,Kka2,kka2_1:8,P00552,0.924553,NO,212,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.904,-2.413,1.509,,,,B,1.59,-0.78,1.708,,42.42,BHO,-0.799667,0.100394,0.0031426,0.924553 kka2_1:1_Q252P,kka2_1:1_252,Kka2,kka2_1:1,P00552,0.924569,NO,252,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.63,-3.996,1.366,,0.906,H,A,0.64,0.35,1.369,,92.05,PPB,-2.20733,0.520039,0.0121001,0.924569 kka2_1:4_L7Y,kka2_1:4_7,Kka2,kka2_1:4,P00552,0.924633,NO,7,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.926,-3.823,1.897,,,,,,,3.012,,71.59,OHB,-2.12333,0.168804,0.00269456,0.924633 beta-lactamase_R189V,beta-lactamase_189,TEM-1,beta-lactamase,P62593,0.924663,NO,189,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.844,-3.783,1.939,5.74877,0.278,H,A,0.68,1.01,1.512,,72.73,HBB,-1.668,0.221079,0.0050699,0.924663 Pab1_L190G,Pab1_190,Pab1,Pab1,P04147,0.924669,NO,190,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.325,-3.456,2.131,,0.489,E,B,,2.59,,,,HHH,-1.31033,0.175299,0.00132347,0.924669 Pab1_S155L,Pab1_155,Pab1,Pab1,P04147,0.924701,NO,155,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.039,-3.018,0.979,,,,,,,,,,PPB,-1.42267,0.175299,0.00208179,0.924701 beta-lactamase_0_L49C,beta-lactamase_0_49,TEM-1,beta-lactamase_0,P62593,0.924781,NO,49,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.897,-4.929,3.032,,0.131,T,A,0.55,0.04,13.838,13.838,64.69,AHP,-1.99233,0.0500837,0.00401477,0.924781 kka2_1:8_A222V,kka2_1:8_222,Kka2,kka2_1:8,P00552,0.924781,NO,222,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.725,-3.107,2.382,,,H,A,1.04,-1.21,,,,HHH,-1.10833,0.100394,0.00207657,0.924781 kka2_1:8_A222V,kka2_1:8_222,Kka2,kka2_1:8,P00552,0.924781,NO,222,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.725,-3.107,2.382,,,H,A,1.04,-1.21,,,,HHH,-1.10833,0.100394,0.00207657,0.924781 PSD95pdz3_S339V,PSD95pdz3_339,PSD95pdz3,PSD95pdz3,P31016,0.924796,NO,339,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.519,-3.21,1.691,5.34493,,,,,12.2167,,,,HPH,-1.55767,0.0758425,0.00084982,0.924796 PSD95pdz3_V328C,PSD95pdz3_328,PSD95pdz3,PSD95pdz3,P31016,0.924834,NO,328,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.465,-4.319,2.854,5.28275,,,,,16.8775,,,,HHO,-1.36767,0.0758425,0.000986706,0.924834 kka2_1:8_T51N,kka2_1:8_51,Kka2,kka2_1:8,P00552,0.924843,NO,51,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.199,-3.862,1.663,,0.05,E,B,0.82,-0.05,5.399,,63.64,BPA,-1.76767,0.100394,0.00628861,0.924843 kka2_1:8_T51N,kka2_1:8_51,Kka2,kka2_1:8,P00552,0.924843,NO,51,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.199,-3.862,1.663,,0.05,E,B,0.82,-0.05,5.399,,63.64,BPA,-1.76767,0.100394,0.00628861,0.924843 kka2_1:8_A108Y,kka2_1:8_108,Kka2,kka2_1:8,P00552,0.924851,NO,108,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.061,-4.432,2.371,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.100394,0.00751209,0.924851 kka2_1:8_A108Y,kka2_1:8_108,Kka2,kka2_1:8,P00552,0.924851,NO,108,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.061,-4.432,2.371,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.100394,0.00751209,0.924851 kka2_1:2_R145G,kka2_1:2_145,Kka2,kka2_1:2,P00552,0.924862,NO,145,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.804,-2.912,1.108,,0.346,H,A,1.2,1.23,7.961,,63.64,HBP,-1.88033,0.295029,0.00846663,0.924862 beta-lactamase_E46F,beta-lactamase_46,TEM-1,beta-lactamase,P62593,0.924872,NO,46,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.94,-4.056,2.116,5.36461,0.021,E,B,1.51,0.14,0.373,,59.44,HAH,-2.079,0.221079,0.00427568,0.924872 beta-lactamase_P165C,beta-lactamase_165,TEM-1,beta-lactamase,P62593,0.924872,NO,165,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.373,-4.892,3.519,5.33889,0.203,T,A,0.99,-0.31,0.414,,73.78,AOA,-1.359,0.221079,0.00549538,0.924872 beta-lactamase_V258A,beta-lactamase_258,TEM-1,beta-lactamase,P62593,0.924872,NO,258,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.975,-1.685,-0.29,5.16083,,E,B,1.64,-1.02,2.124,,67.83,HHH,-1.67667,0.221079,0.007931,0.924872 beta-lactamase_0_G240C,beta-lactamase_0_240,TEM-1,beta-lactamase_0,P62593,0.924893,NO,240,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.0500837,0.00591201,0.924893 beta-lactamase_I283T,beta-lactamase_283,TEM-1,beta-lactamase,P62593,0.924913,NO,283,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.638,-2.636,0.998,5.4178,0.165,H,A,1.23,0.04,1.576,,69.23,HHB,-1.735,0.221079,0.0429138,0.924913 beta-lactamase_2500_E279M,beta-lactamase_2500_279,TEM-1,beta-lactamase_2500,P62593,0.924916,NO,279,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.361275,0.0192826,0.924916 kka2_1:2_A191S,kka2_1:2_191,Kka2,kka2_1:2,P00552,0.924944,NO,191,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.831,-3.052,2.221,,,.,b,0.46,-0.94,2.046,,50,AHO,-0.868667,0.295029,0.00338807,0.924944 beta-lactamase_2500_E195C,beta-lactamase_2500_195,TEM-1,beta-lactamase_2500,P62593,0.924949,NO,195,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.186,-5.238,3.052,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.361275,0.00496565,0.924949 kka2_1:2_E86Q,kka2_1:2_86,Kka2,kka2_1:2,P00552,0.924985,NO,86,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.86,-2.883,1.023,,0.369,.,B,1.04,1.92,3.573,,63.26,PAH,-1.98067,0.295029,0.00642858,0.924985 beta-lactamase_39_S122K,beta-lactamase_39_122,TEM-1,beta-lactamase_39,P62593,0.925006,NO,122,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.406,-3.55,1.144,,0.352,H,A,0.27,-0.54,2.004,,77.62,OPH,-1.39767,0.0495842,0.00497825,0.925006 beta-lactamase_0_Q37R,beta-lactamase_0_37,TEM-1,beta-lactamase_0,P62593,0.925032,NO,37,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.134,-2.096,-0.038,,0.613,H,A,0.64,1.98,4.001,,73.08,APH,-2.06967,0.0500837,0.00425833,0.925032 beta-lactamase_2500_V101Q,beta-lactamase_2500_101,TEM-1,beta-lactamase_2500,P62593,0.925041,NO,101,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.295,-4.106,2.811,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.361275,0.00374492,0.925041 kka2_1:8_A215S,kka2_1:8_215,Kka2,kka2_1:8,P00552,0.92507,NO,215,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.968,-1.873,0.905,,0.039,E,B,1.04,-0.59,2.77,,50.38,HHA,-1.00467,0.100394,0.00529129,0.92507 kka2_1:8_A215S,kka2_1:8_215,Kka2,kka2_1:8,P00552,0.92507,NO,215,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.968,-1.873,0.905,,0.039,E,B,1.04,-0.59,2.77,,50.38,HHA,-1.00467,0.100394,0.00529129,0.92507 kka2_1:8_T125Y,kka2_1:8_125,Kka2,kka2_1:8,P00552,0.925076,NO,125,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.622,-4.422,1.8,,0.791,T,A,0.22,0.33,2.675,,92.05,BPH,-1.56933,0.100394,0.00821755,0.925076 kka2_1:8_T125Y,kka2_1:8_125,Kka2,kka2_1:8,P00552,0.925076,NO,125,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.622,-4.422,1.8,,0.791,T,A,0.22,0.33,2.675,,92.05,BPH,-1.56933,0.100394,0.00821755,0.925076 beta-lactamase_T126I,beta-lactamase_126,TEM-1,beta-lactamase,P62593,0.925084,NO,126,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.122,-3.78,2.658,4.82694,0.05,H,A,0.3,-0.05,1.14,,44.41,HPH,-1.60467,0.221079,0.00244552,0.925084 beta-lactamase_C75G,beta-lactamase_75,TEM-1,beta-lactamase,P62593,0.925099,NO,75,C,G,CG,Special,Special,5.07,3.29388,-1.77612,159,121,75,-46,108.5,60.1,-48.4,-1.245,-2.515,1.27,4.88171,,H,A,0.25,-0.87,0.876,,50,HOO,-1.24333,0.221079,0.0034616,0.925099 kka2_1:4_R258T,kka2_1:4_258,Kka2,kka2_1:4,P00552,0.925119,NO,258,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.626,-2.894,1.268,,0.316,H,A,1.2,-0.85,2.655,,53.03,HBH,-1.25933,0.168804,0.00983174,0.925119 Pab1_D138G,Pab1_138,Pab1,Pab1,P04147,0.925144,NO,138,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.128,-3.054,1.926,,0.427,,B,,-0.03,,,,HAP,-1.13967,0.175299,0.000567877,0.925144 beta-lactamase_P25C,beta-lactamase_25,TEM-1,beta-lactamase,P62593,0.925159,NO,25,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.526,-5.046,3.52,5.6134,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.221079,0.00347571,0.925159 beta-lactamase_0_L38N,beta-lactamase_0_38,TEM-1,beta-lactamase_0,P62593,0.925193,NO,38,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.343,-4.007,2.664,,0.088,H,A,0.55,0.2,13.556,13.556,64.34,PHO,-1.78033,0.0500837,0.00373244,0.925193 beta-lactamase_0_G141V,beta-lactamase_0_141,TEM-1,beta-lactamase_0,P62593,0.925202,NO,141,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.828,-3.79,2.962,,0.575,T,l,0.29,-0.28,0.722,,64.69,HOO,-1.08933,0.0500837,0.0012419,0.925202 kka2_1:1_L174C,kka2_1:1_174,Kka2,kka2_1:1,P00552,0.925215,NO,174,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.952,-4.719,3.767,,,H,A,0.55,-0.31,13.276,13.276,51.89,BHB,-2.08533,0.520039,0.00438501,0.925215 kka2_1:2_A229R,kka2_1:2_229,Kka2,kka2_1:2,P00552,0.925227,NO,229,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.739,-2.242,0.503,,0.32,H,A,0.46,-0.7,6.549,,63.64,HHA,-1.851,0.295029,0.00942138,0.925227 kka2_1:8_A229S,kka2_1:8_229,Kka2,kka2_1:8,P00552,0.925235,NO,229,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.739,-3.404,1.665,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.100394,0.00942138,0.925235 kka2_1:8_A229S,kka2_1:8_229,Kka2,kka2_1:8,P00552,0.925235,NO,229,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.739,-3.404,1.665,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.100394,0.00942138,0.925235 PSD95pdz3_N369W,PSD95pdz3_369,PSD95pdz3,PSD95pdz3,P31016,0.925239,NO,369,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-1.572,-5.228,3.656,5.91569,,,,,24.1262,0.44,,87.71,BPH,-1.487,0.0758425,0.000608412,0.925239 hsp90_G584Y,hsp90_584,hsp90,hsp90,P02829,0.925258,NO,584,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-2.511,-3.316,0,5.20094,0.414,S,b,0.84,0.33,,,,HOH,-3.32733,0.368192,0.000222939,0.925258 beta-lactamase_2500_S80I,beta-lactamase_2500_80,TEM-1,beta-lactamase_2500,P62593,0.925273,NO,80,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.029,-3.787,1.758,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.361275,0.00565569,0.925273 beta-lactamase_F17C,beta-lactamase_17,TEM-1,beta-lactamase,P62593,0.925317,NO,17,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-2.337,-3.057,0.72,,,,,,,2.192,,67.83,HHO,-2.17733,0.221079,0.00216499,0.925317 beta-lactamase_K32T,beta-lactamase_32,TEM-1,beta-lactamase,P62593,0.925317,NO,32,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.984,-2.479,0.495,5.55842,0.563,H,A,1.82,0.34,1.754,,73.08,HBA,-2.04233,0.221079,0.00401283,0.925317 beta-lactamase_L28K,beta-lactamase_28,TEM-1,beta-lactamase,P62593,0.925317,NO,28,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.579,-3.608,2.029,5.42969,0.277,H,A,0.07,-0.16,19.748,19.748,93.01,PHH,-2.11333,0.221079,0.00359321,0.925317 kka2_1:8_W24Q,kka2_1:8_24,Kka2,kka2_1:8,P00552,0.925317,NO,24,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-1.779,-4.365,2.586,,0.477,E,B,1.51,-0.21,2.503,,56.06,AHH,-2.24467,0.100394,0.00631564,0.925317 kka2_1:8_W24Q,kka2_1:8_24,Kka2,kka2_1:8,P00552,0.925317,NO,24,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-1.779,-4.365,2.586,,0.477,E,B,1.51,-0.21,2.503,,56.06,AHH,-2.24467,0.100394,0.00631564,0.925317 beta-lactamase_0_V42N,beta-lactamase_0_42,TEM-1,beta-lactamase_0,P62593,0.92532,NO,42,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.564,-4.165,2.601,,0.017,E,B,0.44,-0.51,1.659,,63.99,BHO,-1.042,0.0500837,0.00404515,0.92532 beta-lactamase_I278M,beta-lactamase_278,TEM-1,beta-lactamase,P62593,0.925372,NO,278,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.348,-4.159,2.811,5.35127,0.015,H,A,0.77,-0.85,2.718,,63.29,AHO,-1.41833,0.221079,0.0310297,0.925372 beta-lactamase_156_T179A,beta-lactamase_156_179,TEM-1,beta-lactamase_156,P62593,0.925391,NO,179,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.085,-2.334,1.249,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.111618,0.00226045,0.925391 beta-lactamase_2500_T264N,beta-lactamase_2500_264,TEM-1,beta-lactamase_2500,P62593,0.925392,NO,264,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.361275,0.0119399,0.925392 Pab1_D138S,Pab1_138,Pab1,Pab1,P04147,0.925468,NO,138,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.128,-3.031,1.903,,0.427,,B,,-0.03,,,,HAP,-1.13967,0.175299,0.000567877,0.925468 kka2_1:8_G164C,kka2_1:8_164,Kka2,kka2_1:8,P00552,0.925482,NO,164,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.869,-5.135,4.266,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.100394,0.00442091,0.925482 kka2_1:8_G164C,kka2_1:8_164,Kka2,kka2_1:8,P00552,0.925482,NO,164,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.869,-5.135,4.266,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.100394,0.00442091,0.925482 beta-lactamase_A170I,beta-lactamase_170,TEM-1,beta-lactamase,P62593,0.925485,NO,170,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.237,-3.643,2.406,5.19261,0.126,,L,2.34,-0.35,2.427,,64.69,AHH,-1.63267,0.221079,0.00431903,0.925485 beta-lactamase_0_N274Q,beta-lactamase_0_274,TEM-1,beta-lactamase_0,P62593,0.925503,NO,274,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-2.082,-3.838,1.756,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.0500837,0.0110418,0.925503 beta-lactamase_2500_E169I,beta-lactamase_2500_169,TEM-1,beta-lactamase_2500,P62593,0.92552,NO,169,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.23,-3.986,2.756,,0.337,,A,1.04,1,1.806,,73.08,PAH,-1.16533,0.361275,0.00400994,0.92552 beta-lactamase_M184V,beta-lactamase_184,TEM-1,beta-lactamase,P62593,0.92552,NO,184,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.593,-2.346,0.753,5.39575,,H,A,1.3,-0.87,2.893,,62.94,HHH,-1.41,0.221079,0.00356019,0.92552 Pab1_F173L,Pab1_173,Pab1,Pab1,P04147,0.925539,NO,173,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.477,-2.89,1.413,,,E,B,0.87,-0.16,1.636,,63.26,BHA,-1.36967,0.175299,0.00148779,0.925539 beta-lactamase_L191V,beta-lactamase_191,TEM-1,beta-lactamase,P62593,0.925556,NO,191,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.087,-2.22,1.133,5.72226,,H,A,1.07,0.09,1.23,,63.29,BHH,-1.445,0.221079,0.00263549,0.925556 beta-lactamase_0_D48A,beta-lactamase_0_48,TEM-1,beta-lactamase_0,P62593,0.925561,NO,48,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.101,-2.565,1.464,,0.189,E,B,0.75,0.21,17.825,17.825,50.35,HAH,-1.62467,0.0500837,0.0027273,0.925561 kka2_1:8_L60D,kka2_1:8_60,Kka2,kka2_1:8,P00552,0.925565,NO,60,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.997,-4.183,3.186,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.100394,0.00262176,0.925565 kka2_1:8_L60D,kka2_1:8_60,Kka2,kka2_1:8,P00552,0.925565,NO,60,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.997,-4.183,3.186,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.100394,0.00262176,0.925565 beta-lactamase_39_M115H,beta-lactamase_39_115,TEM-1,beta-lactamase_39,P62593,0.925566,NO,115,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.389,-4.759,3.37,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.0495842,0.0034337,0.925566 beta-lactamase_0_T193Q,beta-lactamase_0_193,TEM-1,beta-lactamase_0,P62593,0.925659,NO,193,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.914,-4.169,2.255,,0.439,H,a,0.22,0.33,11.546,11.546,63.99,HPO,-1.52133,0.0500837,0.00482669,0.925659 beta-lactamase_T187C,beta-lactamase_187,TEM-1,beta-lactamase,P62593,0.925666,NO,187,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.401,-4.859,3.458,5.11453,0.007,H,A,0.3,-1.19,1.751,,67.48,PPH,-1.69633,0.221079,0.00491782,0.925666 beta-lactamase_2500_H287C,beta-lactamase_2500_287,TEM-1,beta-lactamase_2500,P62593,0.925687,NO,287,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,,,,,,,,,,,,,BBH,-1.111,0.361275,,0.925687 beta-lactamase_0_L135A,beta-lactamase_0_135,TEM-1,beta-lactamase_0,P62593,0.925694,NO,135,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.002,-3.131,2.129,,0.117,H,A,0.55,-0.58,0.705,,43.71,PHH,-1.03767,0.0500837,0.00244423,0.925694 beta-lactamase_0_A183V,beta-lactamase_0_183,TEM-1,beta-lactamase_0,P62593,0.925697,NO,183,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.231,-3.28,2.049,,0.155,H,A,0.46,-0.91,1.48,,77.62,HHH,-1.53367,0.0500837,0.00296631,0.925697 beta-lactamase_39_D113V,beta-lactamase_39_113,TEM-1,beta-lactamase_39,P62593,0.92572,NO,113,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.829,-3.01,1.181,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.0495842,0.00474112,0.92572 kka2_1:2_D134E,kka2_1:2_134,Kka2,kka2_1:2,P00552,0.925741,NO,134,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.969,-2.461,1.492,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.295029,0.00270812,0.925741 Pab1_K166L,Pab1_166,Pab1,Pab1,P04147,0.925757,NO,166,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.262,-3.251,1.989,,0.299,,l,,0,,,,PBO,-1.21033,0.175299,0.0011038,0.925757 beta-lactamase_0_S80T,beta-lactamase_0_80,TEM-1,beta-lactamase_0,P62593,0.92576,NO,80,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.029,-2.845,0.816,,0.192,H,A,0.27,0.46,12.403,12.403,77.62,HPB,-1.44567,0.0500837,0.00565569,0.92576 PSD95pdz3_D348C,PSD95pdz3_348,PSD95pdz3,PSD95pdz3,P31016,0.925762,NO,348,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.264,-4.769,3.505,5.02473,,,,,16.8925,,,,HAH,-1.306,0.0758425,0.000731866,0.925762 beta-lactamase_0_S283T,beta-lactamase_0_283,TEM-1,beta-lactamase_0,P62593,0.925794,NO,283,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.0500837,0.0429138,0.925794 Pab1_N139P,Pab1_139,Pab1,Pab1,P04147,0.925852,NO,139,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-1.079,-3.697,2.618,,0.062,H,A,,-0.73,,,,APB,-1.09667,0.175299,0.000339145,0.925852 beta-lactamase_A77E,beta-lactamase_77,TEM-1,beta-lactamase,P62593,0.92586,NO,77,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.234,-3.61,2.376,4.75777,0.039,H,A,0.52,-0.56,1.708,,64.34,OHH,-1.294,0.221079,0.00282362,0.92586 beta-lactamase_R159Q,beta-lactamase_159,TEM-1,beta-lactamase,P62593,0.92586,NO,159,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-0.94,-3.498,2.558,5.64971,0.316,,B,0.68,-0.55,1.172,,64.34,PBH,-1.011,0.221079,0.00108472,0.92586 beta-lactamase_R162D,beta-lactamase_162,TEM-1,beta-lactamase,P62593,0.92586,NO,162,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.016,-3.754,2.738,5.34456,0.124,S,B,0.68,-0.37,31.656,31.656,64.69,ABH,-1.25,0.221079,0.000561334,0.92586 beta-lactamase_R7F,beta-lactamase_7,TEM-1,beta-lactamase,P62593,0.92586,NO,7,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.683,-3.817,2.134,,,,,,,2.44,,67.13,HBH,-1.96267,0.221079,0.00211375,0.92586 beta-lactamase_0_A225G,beta-lactamase_0_225,TEM-1,beta-lactamase_0,P62593,0.925867,NO,225,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.845,-2.827,0.982,,1,T,B,0.46,-0.38,11.722,11.722,74.48,OHO,-1.39967,0.0500837,0.00465057,0.925867 beta-lactamase_0_D33P,beta-lactamase_0_33,TEM-1,beta-lactamase_0,P62593,0.925919,NO,33,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.321,-3.968,1.647,,0.366,H,A,0.75,0.33,12.514,12.514,77.62,BAH,-2.12133,0.0500837,0.00435556,0.925919 beta-lactamase_0_R202L,beta-lactamase_0_202,TEM-1,beta-lactamase_0,P62593,0.925932,NO,202,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.292,-3.422,2.13,,0.188,H,A,1.2,0.62,7.016,,77.62,PBP,-1.54767,0.0500837,0.00321899,0.925932 beta-lactamase_0_S233D,beta-lactamase_0_233,TEM-1,beta-lactamase_0,P62593,0.925965,NO,233,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.886,-3.5,1.614,,0.016,E,B,0.27,-1.01,3.579,,77.62,BPO,-1.17267,0.0500837,0.00311415,0.925965 kka2_1:4_A255W,kka2_1:4_255,Kka2,kka2_1:4,P00552,0.925981,NO,255,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.715,-5.451,3.736,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.168804,0.0126809,0.925981 beta-lactamase_0_R159W,beta-lactamase_0_159,TEM-1,beta-lactamase_0,P62593,0.926001,NO,159,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-0.94,-5.32,4.38,,0.316,,B,1.2,-0.55,1.426,,64.34,PBH,-1.011,0.0500837,0.00108472,0.926001 beta-lactamase_2500_R176K,beta-lactamase_2500_176,TEM-1,beta-lactamase_2500,P62593,0.926007,NO,176,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-0.863,-2.782,1.919,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.361275,0.00105554,0.926007 kka2_1:8_A64S,kka2_1:8_64,Kka2,kka2_1:8,P00552,0.926018,NO,64,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.496,-3.437,1.941,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.100394,0.00705578,0.926018 kka2_1:8_A64S,kka2_1:8_64,Kka2,kka2_1:8,P00552,0.926018,NO,64,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.496,-3.437,1.941,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.100394,0.00705578,0.926018 beta-lactamase_2500_M270W,beta-lactamase_2500_270,TEM-1,beta-lactamase_2500,P62593,0.926021,NO,270,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.723,,,,0.422,H,A,1.59,1.15,2.029,,64.34,PHA,-1.70933,0.361275,0.00767762,0.926021 beta-lactamase_156_P181L,beta-lactamase_156_181,TEM-1,beta-lactamase_156,P62593,0.926034,NO,181,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.813,-3.546,2.733,,,H,A,0.52,-1.14,1.078,,61.54,HOH,-1.795,0.111618,0.000703122,0.926034 beta-lactamase_156_L47R,beta-lactamase_156_47,TEM-1,beta-lactamase_156,P62593,0.926046,NO,47,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.876,-2.668,0.792,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.111618,0.00439844,0.926046 kka2_1:2_P167A,kka2_1:2_167,Kka2,kka2_1:2,P00552,0.926065,NO,167,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-2.403,-1.382,-1.021,,0.18,H,A,0.52,0.75,3.6,,64.39,HOH,-2.26633,0.295029,0.00543203,0.926065 kka2_1:8_Y218N,kka2_1:8_218,Kka2,kka2_1:8,P00552,0.92608,NO,218,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-1.438,-3.871,2.433,,0.122,H,A,1.25,-0.69,2.923,,56.06,BHP,-1.17533,0.100394,0.0126098,0.92608 kka2_1:8_Y218N,kka2_1:8_218,Kka2,kka2_1:8,P00552,0.92608,NO,218,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-1.438,-3.871,2.433,,0.122,H,A,1.25,-0.69,2.923,,56.06,BHP,-1.17533,0.100394,0.0126098,0.92608 beta-lactamase_0_S80P,beta-lactamase_0_80,TEM-1,beta-lactamase_0,P62593,0.926101,NO,80,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.029,-3.939,1.91,,0.192,H,A,0.27,0.46,12.403,12.403,77.62,HPB,-1.44567,0.0500837,0.00565569,0.926101 beta-lactamase_F58R,beta-lactamase_58,TEM-1,beta-lactamase,P62593,0.926112,NO,58,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-2.914,-2.758,-0.156,5.55634,0.266,E,B,1.33,-0.07,2.467,,77.62,PHB,-2.059,0.221079,0.00523369,0.926112 beta-lactamase_0_A225L,beta-lactamase_0_225,TEM-1,beta-lactamase_0,P62593,0.92613,NO,225,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.845,-2.985,1.14,,1,T,B,0.46,-0.38,11.722,11.722,74.48,OHO,-1.39967,0.0500837,0.00465057,0.92613 kka2_1:4_R44D,kka2_1:4_44,Kka2,kka2_1:4,P00552,0.92614,NO,44,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.062,-3.066,1.004,,0.487,S,B,1.2,-0.35,5.71,,71.59,OBO,-1.80767,0.168804,0.00745043,0.92614 beta-lactamase_2500_L205I,beta-lactamase_2500_205,TEM-1,beta-lactamase_2500,P62593,0.926142,NO,205,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.922,-2.97,2.048,,,H,A,0.55,-0.46,0.831,,42.31,PHH,-1.57767,0.361275,0.00255802,0.926142 beta-lactamase_0_T198Y,beta-lactamase_0_198,TEM-1,beta-lactamase_0,P62593,0.926148,NO,198,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.168,-4.211,2.043,,0.489,,B,0.22,-0.13,9.874,,73.78,HPH,-1.98767,0.0500837,0.004311,0.926148 beta-lactamase_0_V260Q,beta-lactamase_0_260,TEM-1,beta-lactamase_0,P62593,0.92615,NO,260,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.0500837,0.00471757,0.92615 beta-lactamase_0_T263M,beta-lactamase_0_263,TEM-1,beta-lactamase_0,P62593,0.926155,NO,263,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.0500837,0.0110582,0.926155 gb1_T279D,gb1_279,gb1,gb1,P06654,0.926163,NO,279,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.32,-3.418,2.098,,,,,,,0.529,,35.71,HPH,-1.50067,0.177985,0.00421454,0.926163 beta-lactamase_I54Y,beta-lactamase_54,TEM-1,beta-lactamase,P62593,0.926179,NO,54,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-2.838,-4.264,1.426,5.40541,0.669,E,B,0.77,-0.14,3.946,,73.78,BHH,-2.337,0.221079,0.00403589,0.926179 beta-lactamase_M268W,beta-lactamase_268,TEM-1,beta-lactamase,P62593,0.926179,NO,268,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-2.023,-5.039,3.016,5.4797,0.471,H,A,0.09,0.3,1.071,,65.73,PHA,-2.16233,0.221079,0.0102525,0.926179 beta-lactamase_V42W,beta-lactamase_42,TEM-1,beta-lactamase,P62593,0.926179,NO,42,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.564,-5.336,3.772,5.27904,0.017,E,B,1.64,-0.51,2.024,,63.99,BHO,-1.042,0.221079,0.00404515,0.926179 beta-lactamase_2500_M184F,beta-lactamase_2500_184,TEM-1,beta-lactamase_2500,P62593,0.926241,NO,184,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.593,-2.94,1.347,,,H,A,0.55,-0.87,2.893,,62.94,HHH,-1.41,0.361275,0.00356019,0.926241 beta-lactamase_0_A133G,beta-lactamase_0_133,TEM-1,beta-lactamase_0,P62593,0.926242,NO,133,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.186,-1.519,0.333,,,H,A,0.46,-0.86,2.148,,67.83,HHP,-0.988333,0.0500837,0.00468022,0.926242 kka2_1:1_A110E,kka2_1:1_110,Kka2,kka2_1:1,P00552,0.926245,NO,110,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.064,-2.266,0.202,,0.175,H,A,1.04,-1.19,11.755,,71.59,OHA,-1.91867,0.520039,0.00759851,0.926245 beta-lactamase_0_G226V,beta-lactamase_0_226,TEM-1,beta-lactamase_0,P62593,0.926258,NO,226,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.461,-3.807,2.346,,0.701,T,l,0.29,-0.25,23.034,23.034,74.48,HOH,-1.42933,0.0500837,0.00665294,0.926258 PSD95pdz3_I336P,PSD95pdz3_336,PSD95pdz3,PSD95pdz3,P31016,0.926273,NO,336,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.63,-3.786,2.156,5.11321,,,,,13.6363,,,,OHH,-1.38733,0.0758425,0.000887923,0.926273 kka2_1:8_S104D,kka2_1:8_104,Kka2,kka2_1:8,P00552,0.926306,NO,104,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.436,-2.848,1.412,,0.536,T,A,0.27,-1.11,1.689,,63.64,HPP,-1.91433,0.100394,0.00555207,0.926306 kka2_1:8_S104D,kka2_1:8_104,Kka2,kka2_1:8,P00552,0.926306,NO,104,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.436,-2.848,1.412,,0.536,T,A,0.27,-1.11,1.689,,63.64,HPP,-1.91433,0.100394,0.00555207,0.926306 beta-lactamase_625_E195I,beta-lactamase_625_195,TEM-1,beta-lactamase_625,P62593,0.926322,NO,195,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.186,-4.191,2.005,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.213352,0.00496565,0.926322 kka2_1:4_R202L,kka2_1:4_202,Kka2,kka2_1:4,P00552,0.926327,NO,202,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.761,-3.611,1.85,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.168804,0.00696498,0.926327 beta-lactamase_39_T139H,beta-lactamase_39_139,TEM-1,beta-lactamase_39,P62593,0.926354,NO,139,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.901,-3.291,1.39,,0.216,H,A,0.22,0.39,0.421,,77.62,PPH,-2.04667,0.0495842,0.00441837,0.926354 beta-lactamase_0_L248Y,beta-lactamase_0_248,TEM-1,beta-lactamase_0,P62593,0.926357,NO,248,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.0500837,0.00428493,0.926357 kka2_1:4_M178D,kka2_1:4_178,Kka2,kka2_1:4,P00552,0.926368,NO,178,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-3.206,-3.894,0.688,,0.554,.,b,0.55,0.68,9.913,9.913,71.59,BHO,-2.154,0.168804,0.00717253,0.926368 kka2_1:8_L165G,kka2_1:8_165,Kka2,kka2_1:8,P00552,0.926368,NO,165,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-2.453,-3.006,0.553,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.100394,0.00801161,0.926368 kka2_1:8_L165G,kka2_1:8_165,Kka2,kka2_1:8,P00552,0.926368,NO,165,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-2.453,-3.006,0.553,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.100394,0.00801161,0.926368 beta-lactamase_2500_D271C,beta-lactamase_2500_271,TEM-1,beta-lactamase_2500,P62593,0.926382,NO,271,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.361275,0.00752082,0.926382 beta-lactamase_K144W,beta-lactamase_144,TEM-1,beta-lactamase,P62593,0.926389,NO,144,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-2.388,-5.522,3.134,6.02507,0.863,H,A,2.81,1.27,0.515,,77.62,OBA,-1.904,0.221079,0.00481141,0.926389 beta-lactamase_0_E26F,beta-lactamase_0_26,TEM-1,beta-lactamase_0,P62593,0.926405,NO,26,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.454,-4.297,1.843,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.0500837,0.00297948,0.926405 beta-lactamase_625_D48H,beta-lactamase_625_48,TEM-1,beta-lactamase_625,P62593,0.926407,NO,48,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.101,-2.659,1.558,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.213352,0.0027273,0.926407 beta-lactamase_39_L205S,beta-lactamase_39_205,TEM-1,beta-lactamase_39,P62593,0.926408,NO,205,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.922,-3.629,2.707,,,H,A,0.55,-0.46,0.846,,42.31,PHH,-1.57767,0.0495842,0.00255802,0.926408 kka2_1:1_W15R,kka2_1:1_15,Kka2,kka2_1:1,P00552,0.926439,NO,15,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-1.392,-4.195,2.803,,0.01,G,A,0.47,0.15,20.149,20.149,52.27,HHH,-2.10533,0.520039,0.00585505,0.926439 beta-lactamase_I125C,beta-lactamase_125,TEM-1,beta-lactamase,P62593,0.926455,NO,125,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.441,-4.783,3.342,5.23481,,H,A,2.82,-0.7,2.301,,63.29,HHP,-1.248,0.221079,0.00383964,0.926455 beta-lactamase_H285L,beta-lactamase_285,TEM-1,beta-lactamase,P62593,0.92648,NO,285,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-1.845,-2.538,0.693,5.64289,0.312,T,a,0.35,0.64,1.401,,72.73,BBH,-1.64567,0.221079,0.101555,0.92648 kka2_1:2_R18Q,kka2_1:2_18,Kka2,kka2_1:2,P00552,0.926484,NO,18,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.055,-2.59,0.535,,0.474,T,A,1.2,0.54,8.405,8.405,71.59,ABH,-1.821,0.295029,0.00724065,0.926484 beta-lactamase_0_D252L,beta-lactamase_0_252,TEM-1,beta-lactamase_0,P62593,0.926488,NO,252,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.0500837,0.00575769,0.926488 beta-lactamase_39_K213V,beta-lactamase_39_213,TEM-1,beta-lactamase_39,P62593,0.926504,NO,213,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.81,-3.705,1.895,,0.67,,A,2.34,0.29,2.648,,67.83,ABH,-1.57767,0.0495842,0.00610411,0.926504 kka2_1:4_L103T,kka2_1:4_103,Kka2,kka2_1:4,P00552,0.92652,NO,103,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-2.362,-2.414,0.052,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.168804,0.00574792,0.92652 beta-lactamase_0_I45G,beta-lactamase_0_45,TEM-1,beta-lactamase_0,P62593,0.926542,NO,45,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-2.421,-3.565,1.144,,,E,B,0.48,-0.3,1.375,,77.62,HHA,-2.30267,0.0500837,0.00452842,0.926542 kka2_1:8_P132I,kka2_1:8_132,Kka2,kka2_1:8,P00552,0.926578,NO,132,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.775,-4.037,3.262,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.100394,0.0018489,0.926578 kka2_1:8_P132I,kka2_1:8_132,Kka2,kka2_1:8,P00552,0.926578,NO,132,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.775,-4.037,3.262,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.100394,0.0018489,0.926578 E1_Ubiquitin_L73I,E1_Ubiquitin_73,Uba1,E1_Ubiquitin,P0CG63,0.926614,NO,73,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.039,-2.702,1.663,,0.518,,B,1.3,1,,,,BHB,-1.175,0.18783,0.00111236,0.926614 beta-lactamase_39_D113G,beta-lactamase_39_113,TEM-1,beta-lactamase_39,P62593,0.92665,NO,113,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.829,-2.42,0.591,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.0495842,0.00474112,0.92665 PSD95pdz3_F337K,PSD95pdz3_337,PSD95pdz3,PSD95pdz3,P31016,0.926653,NO,337,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.524,-3.589,2.065,5.22838,,,,,13.4936,,,,HHH,-1.59467,0.0758425,0.000875287,0.926653 beta-lactamase_2500_M67C,beta-lactamase_2500_67,TEM-1,beta-lactamase_2500,P62593,0.926659,NO,67,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-2.231,-2.364,0.133,,0.006,G,P,0.55,-0.81,2.653,,65.03,HHP,-1.502,0.361275,0.00409753,0.926659 gb1_G235C,gb1_235,gb1,gb1,P06654,0.926672,NO,235,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.419,-4.648,3.229,,,,,,,0.476,,11.83,POB,-1.86433,0.177985,0.00297491,0.926672 gb1_K239L,gb1_239,gb1,gb1,P06654,0.926672,NO,239,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-3.043,-3.275,0.232,,,,,,,1.326,,45.54,HBO,-2.31467,0.177985,0.00207004,0.926672 kka2_1:8_L232P,kka2_1:8_232,Kka2,kka2_1:8,P00552,0.926676,NO,232,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.514,-4.306,2.792,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.100394,0.00800103,0.926676 kka2_1:8_L232P,kka2_1:8_232,Kka2,kka2_1:8,P00552,0.926676,NO,232,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.514,-4.306,2.792,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.100394,0.00800103,0.926676 PSD95pdz3_R318S,PSD95pdz3_318,PSD95pdz3,PSD95pdz3,P31016,0.926691,NO,318,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.582,-3.067,1.485,4.94876,,,,,17.5609,,,,BBO,-1.40567,0.0758425,0.00110471,0.926691 kka2_1:8_V36G,kka2_1:8_36,Kka2,kka2_1:8,P00552,0.926737,NO,36,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-0.898,-3.694,2.796,,0.292,E,B,1.48,0.21,0.938,,52.27,HHH,-1.484,0.100394,0.00245633,0.926737 kka2_1:8_V36G,kka2_1:8_36,Kka2,kka2_1:8,P00552,0.926737,NO,36,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-0.898,-3.694,2.796,,0.292,E,B,1.48,0.21,0.938,,52.27,HHH,-1.484,0.100394,0.00245633,0.926737 kka2_1:1_R177V,kka2_1:1_177,Kka2,kka2_1:1,P00552,0.926798,NO,177,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.282,-3.636,1.354,,0.521,T,A,1.2,0.16,1.842,,63.64,HBH,-2.36967,0.520039,0.00768224,0.926798 beta-lactamase_0_A282K,beta-lactamase_0_282,TEM-1,beta-lactamase_0,P62593,0.926801,NO,282,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.0500837,0.0449821,0.926801 beta-lactamase_156_M115E,beta-lactamase_156_115,TEM-1,beta-lactamase_156,P62593,0.926809,NO,115,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.389,-3.76,2.371,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.111618,0.0034337,0.926809 beta-lactamase_0_A77E,beta-lactamase_0_77,TEM-1,beta-lactamase_0,P62593,0.926834,NO,77,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.234,-3.61,2.376,,0.039,H,A,0.46,-0.56,2.591,,64.34,OHH,-1.294,0.0500837,0.00282362,0.926834 beta-lactamase_2500_K213H,beta-lactamase_2500_213,TEM-1,beta-lactamase_2500,P62593,0.926872,NO,213,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.81,-4.552,2.742,,0.67,,A,2.34,0.29,1.668,,67.83,ABH,-1.57767,0.361275,0.00610411,0.926872 gb1_G264Y,gb1_264,gb1,gb1,P06654,0.926925,NO,264,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.833,-4.075,2.242,,,,,,,0.864,,44.87,POH,-1.61267,0.177985,0.0049716,0.926925 beta-lactamase_0_I261R,beta-lactamase_0_261,TEM-1,beta-lactamase_0,P62593,0.926934,NO,261,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.0500837,0.0123091,0.926934 beta-lactamase_39_L160W,beta-lactamase_39_160,TEM-1,beta-lactamase_39,P62593,0.926934,NO,160,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.977,-5.194,4.217,,0.022,,B,0.55,-0.6,0.895,,44.41,BHA,-0.936,0.0495842,0.00193775,0.926934 beta-lactamase_0_W288P,beta-lactamase_0_288,TEM-1,beta-lactamase_0,P62593,0.926945,NO,288,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,,,,,,,,,,,,,BHO,,0.0500837,,0.926945 beta-lactamase_625_V214F,beta-lactamase_625_214,TEM-1,beta-lactamase_625,P62593,0.926956,NO,214,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.299,-3.997,2.698,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.213352,0.00628442,0.926956 beta-lactamase_0_Q204C,beta-lactamase_0_204,TEM-1,beta-lactamase_0,P62593,0.926973,NO,204,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-1.382,-5.114,3.732,,0.204,H,A,0.64,0.09,2.646,,66.08,PPH,-1.49067,0.0500837,0.00364106,0.926973 kka2_1:8_L260F,kka2_1:8_260,Kka2,kka2_1:8,P00552,0.927004,NO,260,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.741,-3.645,2.904,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.100394,0.0233782,0.927004 kka2_1:8_L260F,kka2_1:8_260,Kka2,kka2_1:8,P00552,0.927004,NO,260,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.741,-3.645,2.904,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.100394,0.0233782,0.927004 beta-lactamase_2500_V214T,beta-lactamase_2500_214,TEM-1,beta-lactamase_2500,P62593,0.927007,NO,214,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.299,-1.73,0.431,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.361275,0.00628442,0.927007 beta-lactamase_2500_Y44L,beta-lactamase_2500_44,TEM-1,beta-lactamase_2500,P62593,0.927044,NO,44,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-2.547,-2.196,-0.351,,,E,B,0.21,-0.45,2.184,,73.78,OHH,-1.86267,0.361275,0.00426364,0.927044 beta-lactamase_0_L196K,beta-lactamase_0_196,TEM-1,beta-lactamase_0,P62593,0.92706,NO,196,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-2.478,-3.633,1.155,,0.518,S,A,0.55,1.35,6.513,6.513,77.62,AHH,-1.839,0.0500837,0.00512144,0.92706 beta-lactamase_0_N152T,beta-lactamase_0_152,TEM-1,beta-lactamase_0,P62593,0.927081,NO,152,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-2.757,-2.377,-0.38,,0.863,H,A,0.61,0.92,2.151,,77.62,BPH,-2.97,0.0500837,0.00471429,0.927081 kka2_1:2_A64H,kka2_1:2_64,Kka2,kka2_1:2,P00552,0.927087,NO,64,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.496,-4.947,3.451,,0.039,H,A,0.46,-0.57,14.509,14.509,56.06,AHH,-1.334,0.295029,0.00705578,0.927087 beta-lactamase_I278V,beta-lactamase_278,TEM-1,beta-lactamase,P62593,0.927094,NO,278,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.348,-1.899,0.551,5.35127,0.015,H,A,0.77,-0.85,2.718,,63.29,AHO,-1.41833,0.221079,0.0310297,0.927094 beta-lactamase_0_R118M,beta-lactamase_0_118,TEM-1,beta-lactamase_0,P62593,0.927097,NO,118,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.413,-4.747,2.334,,0.457,H,A,1.2,1.39,3.961,,77.62,HBA,-1.785,0.0500837,0.00538794,0.927097 beta-lactamase_2500_A268I,beta-lactamase_2500_268,TEM-1,beta-lactamase_2500,P62593,0.927101,NO,268,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.361275,0.0102525,0.927101 PSD95pdz3_N326G,PSD95pdz3_326,PSD95pdz3,PSD95pdz3,P31016,0.927102,NO,326,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-1.41,-2.59,1.18,5.52537,,,,,19.0688,,,,HPH,-1.52133,0.0758425,0.00101078,0.927102 beta-lactamase_2500_T107C,beta-lactamase_2500_107,TEM-1,beta-lactamase_2500,P62593,0.927126,NO,107,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.117,-4.664,3.547,,,G,A,0.22,-0.06,2.686,,67.83,HPA,-1.265,0.361275,0.00239347,0.927126 kka2_1:8_D157F,kka2_1:8_157,Kka2,kka2_1:8,P00552,0.927131,NO,157,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.993,-4.394,3.401,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.100394,0.0042313,0.927131 kka2_1:8_D157F,kka2_1:8_157,Kka2,kka2_1:8,P00552,0.927131,NO,157,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.993,-4.394,3.401,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.100394,0.0042313,0.927131 beta-lactamase_F6R,beta-lactamase_6,TEM-1,beta-lactamase,P62593,0.927137,NO,6,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.847,-4.077,2.23,,,,,,,1.276,,67.83,BHB,-2.076,0.221079,0.00261627,0.927137 Pab1_S165Y,Pab1_165,Pab1,Pab1,P04147,0.927182,NO,165,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.146,-3.98,2.834,,0.12,,a,,0.11,,,,BPB,-1.56867,0.175299,0.000307838,0.927182 kka2_1:1_H8N,kka2_1:1_8,Kka2,kka2_1:1,P00552,0.927224,NO,8,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-2.759,-3.586,0.827,,,,,,,16.971,16.971,71.59,HBH,-2.25467,0.520039,0.00256422,0.927224 beta-lactamase_0_A185D,beta-lactamase_0_185,TEM-1,beta-lactamase_0,P62593,0.927228,NO,185,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.406,-3.867,2.461,,,H,A,0.46,-1.02,1.203,,65.03,HHP,-1.84033,0.0500837,0.00467449,0.927228 Pab1_F170W,Pab1_170,Pab1,Pab1,P04147,0.927236,NO,170,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.269,-4.233,2.964,,0.331,E,B,0.87,-1.31,2.061,,79.72,OHH,-1.06367,0.175299,0.000540225,0.927236 beta-lactamase_625_L188S,beta-lactamase_625_188,TEM-1,beta-lactamase_625,P62593,0.927245,NO,188,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.166,-3.587,2.421,,,H,A,0.55,-0.3,2.982,,60.14,PHB,-1.47033,0.213352,0.00295687,0.927245 beta-lactamase_2500_A34S,beta-lactamase_2500_34,TEM-1,beta-lactamase_2500,P62593,0.927247,NO,34,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.059,-2.213,0.154,,,H,A,0.46,-0.54,2.921,,73.78,AHA,-1.74967,0.361275,0.00407913,0.927247 kka2_1:2_T28I,kka2_1:2_28,Kka2,kka2_1:2,P00552,0.927306,NO,28,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.883,-3.847,1.964,,0.353,S,B,0.22,2.02,2.655,,63.64,PPH,-1.74467,0.295029,0.00743084,0.927306 kka2_1:4_L67R,kka2_1:4_67,Kka2,kka2_1:4,P00552,0.927312,NO,67,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.741,-3.961,3.22,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.168804,0.00102787,0.927312 beta-lactamase_P253S,beta-lactamase_253,TEM-1,beta-lactamase,P62593,0.927354,NO,253,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-2.253,-2.481,0.228,5.24842,0.308,,B,0.73,-0.46,2.293,,73.08,BOP,-2.10633,0.221079,0.00786358,0.927354 beta-lactamase_0_L111F,beta-lactamase_0_111,TEM-1,beta-lactamase_0,P62593,0.927359,NO,111,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.76,-2.976,1.216,,0.328,T,A,0.55,0.93,1.966,,64.34,BHP,-1.884,0.0500837,0.00480671,0.927359 beta-lactamase_2500_E26Y,beta-lactamase_2500_26,TEM-1,beta-lactamase_2500,P62593,0.927362,NO,26,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.454,-4.272,1.818,,0.54,H,A,1.04,0.98,0.49,,93.01,OAP,-1.96167,0.361275,0.00297948,0.927362 beta-lactamase_0_F64W,beta-lactamase_0_64,TEM-1,beta-lactamase_0,P62593,0.927369,NO,64,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-0.841,-4.422,3.581,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.0500837,0.000947691,0.927369 beta-lactamase_A40M,beta-lactamase_40,TEM-1,beta-lactamase,P62593,0.927411,NO,40,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.402,-4.684,3.282,4.9697,0.155,S,B,1.2,0.21,1.714,,73.78,OHB,-1.40267,0.221079,0.00490026,0.927411 beta-lactamase_E119H,beta-lactamase_119,TEM-1,beta-lactamase,P62593,0.927411,NO,119,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.412,-4.521,3.109,5.33349,0.358,H,A,1.52,0.51,1.983,,63.99,BAH,-1.623,0.221079,0.00386966,0.927411 beta-lactamase_E46L,beta-lactamase_46,TEM-1,beta-lactamase,P62593,0.927411,NO,46,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.94,-2.216,0.276,5.36461,0.021,E,B,1.51,0.14,0.373,,59.44,HAH,-2.079,0.221079,0.00427568,0.927411 beta-lactamase_G194F,beta-lactamase_194,TEM-1,beta-lactamase,P62593,0.927411,NO,194,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.396,-4.382,2.986,5.46622,0.276,S,b,0.77,0.36,3.593,,67.83,POA,-1.832,0.221079,0.00392163,0.927411 beta-lactamase_G279C,beta-lactamase_279,TEM-1,beta-lactamase,P62593,0.927411,NO,279,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.038,-4.906,3.868,4.53882,,H,A,0.46,-0.97,3.066,,62.59,HOH,-1.36467,0.221079,0.0192826,0.927411 beta-lactamase_K109C,beta-lactamase_109,TEM-1,beta-lactamase,P62593,0.927411,NO,109,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.734,-5.237,3.503,6.05842,0.787,G,A,1.82,2.21,21.623,21.623,72.73,ABB,-1.63333,0.221079,0.00462493,0.927411 Ubiquitin_D58G,Ubiquitin_58,Uba1,Ubiquitin,P0CG48,0.927419,NO,58,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.622,-3.395,1.773,5.06391,0.457,G,A,,-0.54,,,,PAH,-1.60267,0.205827,0.000639847,0.927419 Ubiquitin_E34V,Ubiquitin_34,Uba1,Ubiquitin,P0CG48,0.927419,NO,34,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.294,-2.71,1.416,5.02178,0.406,H,A,1.62,0.6,1.295,,35.62,BAO,-1.24933,0.205827,0.000686048,0.927419 Ubiquitin_F45G,Ubiquitin_45,Uba1,Ubiquitin,P0CG48,0.927419,NO,45,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.322,-3.678,2.356,4.80693,0.26,E,B,1.62,-0.99,1.531,,53.87,HHH,-1.55267,0.205827,0.000470401,0.927419 Ubiquitin_G35C,Ubiquitin_35,Uba1,Ubiquitin,P0CG48,0.927419,NO,35,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.171,-5.032,3.861,4.96213,0.713,,L,,0.2,,,,AOH,-1.314,0.205827,0.000648878,0.927419 Ubiquitin_I23F,Ubiquitin_23,Uba1,Ubiquitin,P0CG48,0.927419,NO,23,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.325,-2.742,1.417,4.67534,,H,A,0.01,-0.93,0.515,,52.12,PHA,-1.54033,0.205827,0.000621252,0.927419 Ubiquitin_I23S,Ubiquitin_23,Uba1,Ubiquitin,P0CG48,0.927419,NO,23,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.325,-3.575,2.25,4.67534,,H,A,0.01,-0.93,0.515,,52.12,PHA,-1.54033,0.205827,0.000621252,0.927419 Ubiquitin_K27Q,Ubiquitin_27,Uba1,Ubiquitin,P0CG48,0.927419,NO,27,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.064,-3.514,2.45,4.77438,0.086,H,A,2.89,-0.74,2.662,,27.01,HBH,-1.42667,0.205827,0.000767556,0.927419 Ubiquitin_K33Y,Ubiquitin_33,Uba1,Ubiquitin,P0CG48,0.927419,NO,33,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.283,-4.155,2.872,5.08526,0.64,H,A,1.82,1.2,1.509,,51.09,ABA,-1.34267,0.205827,0.000712743,0.927419 Ubiquitin_K63W,Ubiquitin_63,Uba1,Ubiquitin,P0CG48,0.927419,NO,63,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.635,-5.491,3.856,5.08297,0.721,T,B,,0.59,,,,PBA,-1.74467,0.205827,0.000607964,0.927419 Ubiquitin_N25W,Ubiquitin_25,Uba1,Ubiquitin,P0CG48,0.927419,NO,25,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-1.95,-5.458,3.508,4.76563,0.444,H,A,0.09,0,2.3,,31.09,APH,-1.741,0.205827,0.00071919,0.927419 Ubiquitin_N60Q,Ubiquitin_60,Uba1,Ubiquitin,P0CG48,0.927419,NO,60,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-1.775,-3.901,2.126,5.00332,0.775,T,L,,0.33,,,,HPH,-1.532,0.205827,0.000814061,0.927419 Ubiquitin_Q40V,Ubiquitin_40,Uba1,Ubiquitin,P0CG48,0.927419,NO,40,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-1.752,-3.546,1.794,4.7807,0.387,G,A,,0.03,,,,APP,-1.62433,0.205827,0.000619089,0.927419 Ubiquitin_Q41L,Ubiquitin_41,Uba1,Ubiquitin,P0CG48,0.927419,NO,41,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-1.329,-2.298,0.969,4.9201,0.017,E,B,0.12,-0.98,0.812,,30.07,PPB,-1.55067,0.205827,0.000521668,0.927419 Ubiquitin_Q49A,Ubiquitin_49,Uba1,Ubiquitin,P0CG48,0.927419,NO,49,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-1.941,-3.196,1.255,5.05026,0.403,E,B,,-0.59,,,,BPH,-1.49467,0.205827,0.000613067,0.927419 Ubiquitin_R54E,Ubiquitin_54,Uba1,Ubiquitin,P0CG48,0.927419,NO,54,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.037,-2.604,0.567,5.14935,0.41,S,B,,0.87,,,,OBP,-1.72667,0.205827,0.000581095,0.927419 Ubiquitin_S57P,Ubiquitin_57,Uba1,Ubiquitin,P0CG48,0.927419,NO,57,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.879,-2.699,0.82,4.65125,0.456,G,A,,-0.42,,,,HPA,-1.60833,0.205827,0.000948086,0.927419 Ubiquitin_S65I,Ubiquitin_65,Uba1,Ubiquitin,P0CG48,0.927419,NO,65,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.535,-2.988,1.453,4.99442,0.168,,b,0.25,-0.68,16.756,16.756,33.87,APP,-1.626,0.205827,0.000546776,0.927419 Ubiquitin_T12C,Ubiquitin_12,Uba1,Ubiquitin,P0CG48,0.927419,NO,12,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.288,-4.752,3.464,4.93973,0.417,E,B,0.8,0.12,2.762,,25.84,BPH,-1.39867,0.205827,0.000657544,0.927419 Ubiquitin_T7C,Ubiquitin_7,Uba1,Ubiquitin,P0CG48,0.927419,NO,7,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.415,-4.78,3.365,4.954,0.094,E,B,0.43,-0.78,0.805,,21.31,BPH,-1.41033,0.205827,0.000647855,0.927419 Ubiquitin_T7N,Ubiquitin_7,Uba1,Ubiquitin,P0CG48,0.927419,NO,7,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.415,-2.696,1.281,4.954,0.094,E,B,0.43,-0.78,0.805,,21.31,BPH,-1.41033,0.205827,0.000647855,0.927419 Ubiquitin_T9L,Ubiquitin_9,Uba1,Ubiquitin,P0CG48,0.927419,NO,9,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.409,-3.236,1.827,5.24336,0.777,T,A,2.12,-0.12,2.705,,29.93,HPO,-1.50933,0.205827,0.000630716,0.927419 Ubiquitin_V5M,Ubiquitin_5,Uba1,Ubiquitin,P0CG48,0.927419,NO,5,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.576,-4.205,2.629,4.75677,,E,B,,-0.82,,,,HHB,-1.401,0.205827,0.000796998,0.927419 Ubiquitin_V70I,Ubiquitin_70,Uba1,Ubiquitin,P0CG48,0.927419,NO,70,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.874,-2.455,0.581,5.29728,0.05,E,B,0.96,-0.97,2.363,,34.31,HHH,-1.65533,0.205827,0.00106871,0.927419 PSD95pdz3_L367A,PSD95pdz3_367,PSD95pdz3,PSD95pdz3,P31016,0.927482,NO,367,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.347,-2.759,1.412,5.47696,,,,,17.0063,,,,AHB,-1.39767,0.0758425,0.000466436,0.927482 Pab1_V148F,Pab1_148,Pab1,Pab1,P04147,0.927499,NO,148,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.875,-3.975,2.1,,,,,,,,,,PHH,-1.43033,0.175299,0.00179641,0.927499 hsp90_W585M,hsp90_585,hsp90,hsp90,P02829,0.92751,NO,585,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-4.251,-3.858,0,5.31455,0.508,,B,1.22,0.43,,,,OHP,-3.17533,0.368192,0.000222939,0.92751 beta-lactamase_2500_L223A,beta-lactamase_2500_223,TEM-1,beta-lactamase_2500,P62593,0.927513,NO,223,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.055,-3.102,2.047,,0.27,,B,0.55,0.09,1.334,,74.48,HHO,-1.35033,0.361275,0.00372793,0.927513 kka2_1:8_S105R,kka2_1:8_105,Kka2,kka2_1:8,P00552,0.927517,NO,105,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.945,-3.214,1.269,,0.056,S,B,0.27,-1.04,2.115,,65.53,PPB,-2.17033,0.100394,0.00847233,0.927517 kka2_1:8_S105R,kka2_1:8_105,Kka2,kka2_1:8,P00552,0.927517,NO,105,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.945,-3.214,1.269,,0.056,S,B,0.27,-1.04,2.115,,65.53,PPB,-2.17033,0.100394,0.00847233,0.927517 beta-lactamase_39_Q203C,beta-lactamase_39_203,TEM-1,beta-lactamase_39,P62593,0.927545,NO,203,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.168,-5.086,2.918,,0.47,H,A,0.64,-0.38,1.453,,65.38,BPP,-1.614,0.0495842,0.00631514,0.927545 beta-lactamase_0_L73T,beta-lactamase_0_73,TEM-1,beta-lactamase_0,P62593,0.927578,NO,73,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.507,-3.582,2.075,,,H,A,0.55,-0.64,0.877,,67.83,HHH,-1.487,0.0500837,0.00488983,0.927578 beta-lactamase_39_V259W,beta-lactamase_39_259,TEM-1,beta-lactamase_39,P62593,0.927593,NO,259,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.0495842,0.0070773,0.927593 beta-lactamase_I244L,beta-lactamase_244,TEM-1,beta-lactamase,P62593,0.927595,NO,244,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.555,-2.697,1.142,5.35885,,E,B,0.01,-0.84,0.379,,77.62,HHH,-1.385,0.221079,0.00605379,0.927595 beta-lactamase_2500_E272C,beta-lactamase_2500_272,TEM-1,beta-lactamase_2500,P62593,0.9276,NO,272,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.361275,0.00545371,0.9276 beta-lactamase_625_G85I,beta-lactamase_625_85,TEM-1,beta-lactamase_625,P62593,0.927629,NO,85,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.011,-4.226,3.215,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.213352,0.00252173,0.927629 beta-lactamase_39_T158H,beta-lactamase_39_158,TEM-1,beta-lactamase_39,P62593,0.927631,NO,158,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.116,-4.689,3.573,,0.036,,B,0.22,-0.85,2.755,,69.58,HPB,-1.269,0.0495842,0.00341825,0.927631 beta-lactamase_39_D231K,beta-lactamase_39_231,TEM-1,beta-lactamase_39,P62593,0.927639,NO,231,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.816,-3.42,2.604,,,E,B,0.75,-1.06,0.462,,65.38,HAB,-0.994,0.0495842,0.00107395,0.927639 beta-lactamase_2500_D33F,beta-lactamase_2500_33,TEM-1,beta-lactamase_2500,P62593,0.927659,NO,33,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.321,-4.288,1.967,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.361275,0.00435556,0.927659 beta-lactamase_0_D36R,beta-lactamase_0_36,TEM-1,beta-lactamase_0,P62593,0.927684,NO,36,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.732,-2.847,0.115,,0.555,H,A,0.75,1.17,13.689,13.689,77.62,AAP,-1.91167,0.0500837,0.00476483,0.927684 beta-lactamase_625_L100W,beta-lactamase_625_100,TEM-1,beta-lactamase_625,P62593,0.92769,NO,100,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.218,-5.168,3.95,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.213352,0.00413885,0.92769 beta-lactamase_156_D212I,beta-lactamase_156_212,TEM-1,beta-lactamase_156,P62593,0.927713,NO,212,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.624,-3.045,1.421,,0.037,,b,0.75,-0.58,20.222,20.222,74.48,HAB,-1.77667,0.111618,0.00644302,0.927713 beta-lactamase_625_G141C,beta-lactamase_625_141,TEM-1,beta-lactamase_625,P62593,0.927727,NO,141,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.828,-5.167,4.339,,0.575,T,l,0.29,-0.28,0.198,,64.69,HOO,-1.08933,0.213352,0.0012419,0.927727 beta-lactamase_0_L192G,beta-lactamase_0_192,TEM-1,beta-lactamase_0,P62593,0.927748,NO,192,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.254,-3.698,2.444,,0.095,H,A,0.55,0.35,1.756,,60.14,HHP,-1.41833,0.0500837,0.00558728,0.927748 beta-lactamase_2500_T126M,beta-lactamase_2500_126,TEM-1,beta-lactamase_2500,P62593,0.92779,NO,126,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.122,-4.659,3.537,,0.05,H,A,0.22,-0.05,0.817,,44.41,HPH,-1.60467,0.361275,0.00244552,0.92779 beta-lactamase_V106C,beta-lactamase_106,TEM-1,beta-lactamase,P62593,0.927793,NO,106,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.218,-4.774,3.556,5.23115,0.258,T,A,0.96,0.24,1.188,,72.73,OHP,-1.04933,0.221079,0.00304168,0.927793 beta-lactamase_K190I,beta-lactamase_190,TEM-1,beta-lactamase,P62593,0.927834,NO,190,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.994,-3.984,1.99,5.49163,0.371,H,A,1.82,0.16,29.753,29.753,77.62,BBH,-1.64167,0.221079,0.00574527,0.927834 beta-lactamase_0_L188A,beta-lactamase_0_188,TEM-1,beta-lactamase_0,P62593,0.927843,NO,188,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.166,-2.542,1.376,,,H,A,0.55,-0.3,2.739,,60.14,PHB,-1.47033,0.0500837,0.00295687,0.927843 beta-lactamase_0_E26Q,beta-lactamase_0_26,TEM-1,beta-lactamase_0,P62593,0.927848,NO,26,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.454,-2.296,-0.158,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.0500837,0.00297948,0.927848 kka2_1:1_P167M,kka2_1:1_167,Kka2,kka2_1:1,P00552,0.927876,NO,167,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-2.403,-4.574,2.171,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.520039,0.00543203,0.927876 beta-lactamase_0_G253P,beta-lactamase_0_253,TEM-1,beta-lactamase_0,P62593,0.927918,NO,253,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-2.253,-2.791,0.538,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.0500837,0.00786358,0.927918 kka2_1:2_A129D,kka2_1:2_129,Kka2,kka2_1:2,P00552,0.927923,NO,129,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.656,-2.499,0.843,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.295029,0.00726862,0.927923 gb1_L233S,gb1_233,gb1,gb1,P06654,0.927936,NO,233,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-2.678,-3.283,0.605,,,,,,,0.822,,45.54,HHP,-2.30267,0.177985,0.00266958,0.927936 beta-lactamase_0_A170M,beta-lactamase_0_170,TEM-1,beta-lactamase_0,P62593,0.92795,NO,170,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.237,-4.595,3.358,,0.126,,L,0.46,-0.35,2.427,,64.69,AHH,-1.63267,0.0500837,0.00431903,0.92795 kka2_1:8_L241H,kka2_1:8_241,Kka2,kka2_1:8,P00552,0.927967,NO,241,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.158,-4.825,3.667,,0.08,H,A,1.59,-0.82,1.136,,63.26,HHH,-1.58533,0.100394,0.0117299,0.927967 kka2_1:8_L241H,kka2_1:8_241,Kka2,kka2_1:8,P00552,0.927967,NO,241,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.158,-4.825,3.667,,0.08,H,A,1.59,-0.82,1.136,,63.26,HHH,-1.58533,0.100394,0.0117299,0.927967 beta-lactamase_0_E56T,beta-lactamase_0_56,TEM-1,beta-lactamase_0,P62593,0.927994,NO,56,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.043,-2.013,-0.03,,0.198,E,B,1.04,0.31,1.491,,72.73,HAP,-1.94033,0.0500837,0.00238534,0.927994 WW_domain_K181T,WW_domain_181,Yap65,WW_domain,P46937,0.928037,NO,181,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.35,-3.321,1.971,5.0864,,,,,,0.176,,15.87,HBP,-1.247,0.153962,0.0033022,0.928037 hsp90_Q582W,hsp90_582,hsp90,hsp90,P02829,0.92806,NO,582,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-3.278,-4.251,0,4.91603,0.453,S,B,,0.67,,,,OPH,-3.249,0.368192,0.000222939,0.92806 beta-lactamase_A246S,beta-lactamase_246,TEM-1,beta-lactamase,P62593,0.928065,NO,246,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.121,-3.607,1.486,4.78979,0.01,E,B,0.52,-1.01,1.26,,73.78,HHH,-1.55633,0.221079,0.00569458,0.928065 beta-lactamase_R7S,beta-lactamase_7,TEM-1,beta-lactamase,P62593,0.928065,NO,7,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.683,-3.414,1.731,,,,,,,2.44,,67.13,HBH,-1.96267,0.221079,0.00211375,0.928065 Pab1_Y143W,Pab1_143,Pab1,Pab1,P04147,0.928078,NO,143,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-1.961,-4.582,2.621,,0.409,H,A,,0.3,,,,HHA,-1.39633,0.175299,0.00160364,0.928078 beta-lactamase_39_A225Q,beta-lactamase_39_225,TEM-1,beta-lactamase_39,P62593,0.928133,NO,225,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.845,-2.909,1.064,,1,T,B,0.46,-0.38,9.874,9.874,74.48,OHO,-1.39967,0.0495842,0.00465057,0.928133 beta-lactamase_L10Y,beta-lactamase_10,TEM-1,beta-lactamase,P62593,0.928146,NO,10,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.623,-3.878,2.255,,,,,,,2.467,,65.38,HHH,-1.83833,0.221079,0.00296968,0.928146 beta-lactamase_L38T,beta-lactamase_38,TEM-1,beta-lactamase,P62593,0.928146,NO,38,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.343,-3.495,2.152,5.23728,0.088,H,A,1.75,0.2,1.986,,64.34,PHO,-1.78033,0.221079,0.00373244,0.928146 kka2_1:4_D127Q,kka2_1:4_127,Kka2,kka2_1:4,P00552,0.928169,NO,127,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.364,-3.882,2.518,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.168804,0.00660501,0.928169 beta-lactamase_0_G265D,beta-lactamase_0_265,TEM-1,beta-lactamase_0,P62593,0.928188,NO,265,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.0500837,0.00811926,0.928188 kka2_1:2_F37W,kka2_1:2_37,Kka2,kka2_1:2,P00552,0.928202,NO,37,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.427,-2.717,1.29,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.295029,0.00586193,0.928202 kka2_1:2_Q136A,kka2_1:2_136,Kka2,kka2_1:2,P00552,0.928252,NO,136,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-3.021,-3.149,0.128,,0.331,,b,0.4,0.96,2.726,,92.05,BPH,-2.16933,0.295029,0.00624149,0.928252 beta-lactamase_0_G142Y,beta-lactamase_0_142,TEM-1,beta-lactamase_0,P62593,0.928274,NO,142,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.707,-4.385,3.678,,0.034,,p,0.29,-0.64,1.947,,64.69,OOO,-0.834,0.0500837,0.00060149,0.928274 kka2_1:1_R44G,kka2_1:1_44,Kka2,kka2_1:1,P00552,0.928279,NO,44,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.062,-2.106,0.044,,0.487,S,B,1.2,-0.35,2.717,,71.59,OBO,-1.80767,0.520039,0.00745043,0.928279 beta-lactamase_0_G265W,beta-lactamase_0_265,TEM-1,beta-lactamase_0,P62593,0.928287,NO,265,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.0500837,0.00811926,0.928287 kka2_1:4_I141Y,kka2_1:4_141,Kka2,kka2_1:4,P00552,0.928294,NO,141,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.495,-4.112,2.617,,0.068,H,A,0.48,-0.01,2.144,,92.05,BHA,-1.689,0.168804,0.00744745,0.928294 beta-lactamase_156_M115H,beta-lactamase_156_115,TEM-1,beta-lactamase_156,P62593,0.928303,NO,115,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.389,-4.759,3.37,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.111618,0.0034337,0.928303 beta-lactamase_0_E195Q,beta-lactamase_0_195,TEM-1,beta-lactamase_0,P62593,0.928332,NO,195,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.186,-2.527,0.341,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.0500837,0.00496565,0.928332 beta-lactamase_39_E272Y,beta-lactamase_39_272,TEM-1,beta-lactamase_39,P62593,0.928346,NO,272,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.127,,,,0.081,H,A,0.43,-0.97,12.983,12.983,63.64,AAB,-1.56333,0.0495842,0.00545371,0.928346 beta-lactamase_2500_V101M,beta-lactamase_2500_101,TEM-1,beta-lactamase_2500,P62593,0.928349,NO,101,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.295,-2.812,1.517,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.361275,0.00374492,0.928349 beta-lactamase_G154E,beta-lactamase_154,TEM-1,beta-lactamase,P62593,0.928354,NO,154,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.823,-3.512,2.689,5.40944,0.54,T,l,0.77,-0.56,2.283,,64.69,HOA,-1.635,0.221079,0.00180205,0.928354 beta-lactamase_L55R,beta-lactamase_55,TEM-1,beta-lactamase,P62593,0.928354,NO,55,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.86,-3.1,1.24,,0.372,E,A,1.07,-0.36,1.423,,63.99,HHA,-2.247,0.221079,0.00403741,0.928354 PSD95pdz3_I389E,PSD95pdz3_389,PSD95pdz3,PSD95pdz3,P31016,0.928367,NO,389,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.628,-3.571,1.943,5.15116,,,,,14.8038,1.498,,87.71,HHH,-1.52167,0.0758425,0.00148097,0.928367 kka2_1:8_L165P,kka2_1:8_165,Kka2,kka2_1:8,P00552,0.928376,NO,165,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-2.453,-3.229,0.776,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.100394,0.00801161,0.928376 kka2_1:8_L165P,kka2_1:8_165,Kka2,kka2_1:8,P00552,0.928376,NO,165,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-2.453,-3.229,0.776,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.100394,0.00801161,0.928376 kka2_1:4_R18L,kka2_1:4_18,Kka2,kka2_1:4,P00552,0.928403,NO,18,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.055,-2.54,0.485,,0.474,T,A,1.2,0.54,8.405,8.405,71.59,ABH,-1.821,0.168804,0.00724065,0.928403 kka2_1:4_M148K,kka2_1:4_148,Kka2,kka2_1:4,P00552,0.928405,NO,148,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.847,-3.762,1.915,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.168804,0.00982664,0.928405 kka2_1:2_T28M,kka2_1:2_28,Kka2,kka2_1:2,P00552,0.928415,NO,28,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.883,-3.567,1.684,,0.353,S,B,0.22,2.02,2.655,,63.64,PPH,-1.74467,0.295029,0.00743084,0.928415 kka2_1:2_A108R,kka2_1:2_108,Kka2,kka2_1:2,P00552,0.928416,NO,108,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.061,-4.036,1.975,,0.243,.,B,0.46,-1.34,2.462,,71.59,HHO,-1.57033,0.295029,0.00751209,0.928416 kka2_1:2_G55F,kka2_1:2_55,Kka2,kka2_1:2,P00552,0.928489,NO,55,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.625,-3.32,1.695,,0.517,S,b,0.75,1.19,15.753,15.753,63.64,POH,-2.05967,0.295029,0.00667877,0.928489 PSD95pdz3_P346E,PSD95pdz3_346,PSD95pdz3,PSD95pdz3,P31016,0.92851,NO,346,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.236,-3.122,1.886,5.02406,,,,,14.6629,,,,OOH,-1.18367,0.0758425,0.000758563,0.92851 beta-lactamase_156_A268I,beta-lactamase_156_268,TEM-1,beta-lactamase_156,P62593,0.928521,NO,268,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.111618,0.0102525,0.928521 beta-lactamase_0_S57R,beta-lactamase_0_57,TEM-1,beta-lactamase_0,P62593,0.928551,NO,57,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.918,-3.069,1.151,,0.352,E,B,0.27,-0.18,1.454,,72.73,APH,-2.29167,0.0500837,0.00492804,0.928551 beta-lactamase_A211F,beta-lactamase_211,TEM-1,beta-lactamase,P62593,0.928574,NO,211,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.896,-4.364,2.468,5.54662,0.369,T,A,0.52,-0.69,2.061,,77.62,AHA,-1.94633,0.221079,0.00648183,0.928574 beta-lactamase_A34F,beta-lactamase_34,TEM-1,beta-lactamase,P62593,0.928574,NO,34,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.059,-3.937,1.878,4.9129,,H,A,0.75,-0.54,3.614,,73.78,AHA,-1.74967,0.221079,0.00407913,0.928574 beta-lactamase_F14Y,beta-lactamase_14,TEM-1,beta-lactamase,P62593,0.928574,NO,14,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-2.736,-3.914,1.178,,,,,,,1.537,,93.01,HHH,-2.26133,0.221079,0.00277095,0.928574 beta-lactamase_R81S,beta-lactamase_81,TEM-1,beta-lactamase,P62593,0.928574,NO,81,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.466,-3.386,1.92,5.12166,0.218,H,A,0.68,1.66,1.236,,50,PBH,-1.60667,0.221079,0.00499763,0.928574 beta-lactamase_T27I,beta-lactamase_27,TEM-1,beta-lactamase,P62593,0.928574,NO,27,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.905,-3.752,1.847,5.39752,0.007,H,A,0.69,-0.37,0.745,,93.01,APH,-1.97933,0.221079,0.00306559,0.928574 kka2_1:8_I221M,kka2_1:8_221,Kka2,kka2_1:8,P00552,0.92858,NO,221,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.739,-4.064,2.325,,,H,A,1.52,-1.15,1.599,,71.59,AHH,-1.08367,0.100394,0.00945908,0.92858 kka2_1:8_I221M,kka2_1:8_221,Kka2,kka2_1:8,P00552,0.92858,NO,221,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.739,-4.064,2.325,,,H,A,1.52,-1.15,1.599,,71.59,AHH,-1.08367,0.100394,0.00945908,0.92858 beta-lactamase_39_A268I,beta-lactamase_39_268,TEM-1,beta-lactamase_39,P62593,0.928586,NO,268,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.0495842,0.0102525,0.928586 beta-lactamase_0_A246N,beta-lactamase_0_246,TEM-1,beta-lactamase_0,P62593,0.928603,NO,246,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.121,-4.23,2.109,,0.01,E,B,0.46,-1.01,1.201,,73.78,HHH,-1.55633,0.0500837,0.00569458,0.928603 PSD95pdz3_E373N,PSD95pdz3_373,PSD95pdz3,PSD95pdz3,P31016,0.928654,NO,373,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.404,-3.13,1.726,5.79743,,,,,27.9833,,,,BAP,-1.57667,0.0758425,0.000387698,0.928654 beta-lactamase_0_W288G,beta-lactamase_0_288,TEM-1,beta-lactamase_0,P62593,0.928663,NO,288,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,,,,,,,,,,,,,BHO,,0.0500837,,0.928663 beta-lactamase_0_Y103R,beta-lactamase_0_103,TEM-1,beta-lactamase_0,P62593,0.928673,NO,103,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-1.33,-3.864,2.534,,0.613,S,l,0.21,1.21,1.646,,63.29,AHP,-1.48767,0.0500837,0.00443048,0.928673 beta-lactamase_0_D33V,beta-lactamase_0_33,TEM-1,beta-lactamase_0,P62593,0.928704,NO,33,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.321,-3.488,1.167,,0.366,H,A,0.75,0.33,12.514,12.514,77.62,BAH,-2.12133,0.0500837,0.00435556,0.928704 PSD95pdz3_D348M,PSD95pdz3_348,PSD95pdz3,PSD95pdz3,P31016,0.92871,NO,348,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.264,-4.612,3.348,5.02473,,,,,16.8925,,,,HAH,-1.306,0.0758425,0.000731866,0.92871 beta-lactamase_S221F,beta-lactamase_221,TEM-1,beta-lactamase,P62593,0.928748,NO,221,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.754,-4.221,2.467,5.77407,0.624,H,A,0.74,-0.2,0.383,,74.48,BPH,-1.59967,0.221079,0.0046094,0.928748 beta-lactamase_D113V,beta-lactamase_113,TEM-1,beta-lactamase,P62593,0.928807,NO,113,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.829,-3.01,1.181,6.04499,0.665,T,A,0.23,0.91,21.104,21.104,73.08,PAO,-1.703,0.221079,0.00474112,0.928807 beta-lactamase_2500_K32W,beta-lactamase_2500_32,TEM-1,beta-lactamase_2500,P62593,0.928817,NO,32,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.984,-5.48,3.496,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.361275,0.00401283,0.928817 beta-lactamase_2500_W163L,beta-lactamase_2500_163,TEM-1,beta-lactamase_2500,P62593,0.928823,NO,163,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-1.843,-2.838,0.995,,0.467,,B,0.47,-0.5,32.624,32.624,63.99,BHA,-1.269,0.361275,0.00418955,0.928823 kka2_1:4_I29S,kka2_1:4_29,Kka2,kka2_1:4,P00552,0.928862,NO,29,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.692,-3.624,1.932,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.168804,0.00619521,0.928862 beta-lactamase_625_S122M,beta-lactamase_625_122,TEM-1,beta-lactamase_625,P62593,0.928895,NO,122,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.406,-4.704,2.298,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.213352,0.00497825,0.928895 kka2_1:4_Q100H,kka2_1:4_100,Kka2,kka2_1:4,P00552,0.928908,NO,100,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.77,-2.906,0.136,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.168804,0.0066405,0.928908 kka2_1:2_P167T,kka2_1:2_167,Kka2,kka2_1:2,P00552,0.928916,NO,167,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-2.403,-2.47,0.067,,0.18,H,A,0.52,0.75,3.6,,64.39,HOH,-2.26633,0.295029,0.00543203,0.928916 beta-lactamase_0_R257C,beta-lactamase_0_257,TEM-1,beta-lactamase_0,P62593,0.928927,NO,257,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.0500837,0.00756629,0.928927 kka2_1:4_R239I,kka2_1:4_239,Kka2,kka2_1:4,P00552,0.928931,NO,239,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.949,-3.142,0.193,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.168804,0.00835326,0.928931 beta-lactamase_0_T112L,beta-lactamase_0_112,TEM-1,beta-lactamase_0,P62593,0.928959,NO,112,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.186,-3.575,1.389,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.0500837,0.00531334,0.928959 kka2_1:4_R147C,kka2_1:4_147,Kka2,kka2_1:4,P00552,0.928961,NO,147,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.123,-5.216,4.093,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.168804,0.00549168,0.928961 beta-lactamase_2500_S201N,beta-lactamase_2500_201,TEM-1,beta-lactamase_2500,P62593,0.929003,NO,201,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.183,-3.471,2.288,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.361275,0.00198815,0.929003 beta-lactamase_0_Q204S,beta-lactamase_0_204,TEM-1,beta-lactamase_0,P62593,0.929008,NO,204,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-1.382,-3.344,1.962,,0.204,H,A,0.64,0.09,2.646,,66.08,PPH,-1.49067,0.0500837,0.00364106,0.929008 kka2_1:4_A137T,kka2_1:4_137,Kka2,kka2_1:4,P00552,0.929037,NO,137,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.156,-3.52,1.364,,0.029,H,A,0.46,0.34,2.227,,63.26,PHB,-2.559,0.168804,0.00515054,0.929037 beta-lactamase_0_G249A,beta-lactamase_0_249,TEM-1,beta-lactamase_0,P62593,0.929041,NO,249,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.0500837,0.00220169,0.929041 beta-lactamase_2500_S283C,beta-lactamase_2500_283,TEM-1,beta-lactamase_2500,P62593,0.929082,NO,283,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.361275,0.0429138,0.929082 PSD95pdz3_S339G,PSD95pdz3_339,PSD95pdz3,PSD95pdz3,P31016,0.929084,NO,339,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.519,-2.59,1.071,5.34493,,,,,12.2167,,,,HPH,-1.55767,0.0758425,0.00084982,0.929084 beta-lactamase_0_T264C,beta-lactamase_0_264,TEM-1,beta-lactamase_0,P62593,0.929093,NO,264,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.0500837,0.0119399,0.929093 beta-lactamase_2500_I245M,beta-lactamase_2500_245,TEM-1,beta-lactamase_2500,P62593,0.929107,NO,245,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.361275,0.00391032,0.929107 beta-lactamase_0_N98P,beta-lactamase_0_98,TEM-1,beta-lactamase_0,P62593,0.929109,NO,98,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-2.973,-3.946,0.973,,0.963,G,A,0.61,1.35,14.853,14.853,77.62,PPA,-2.07867,0.0500837,0.00505389,0.929109 beta-lactamase_39_A246W,beta-lactamase_39_246,TEM-1,beta-lactamase_39,P62593,0.929146,NO,246,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.121,-5.267,3.146,,0.01,E,B,0.46,-1.01,1.331,,73.78,HHH,-1.55633,0.0495842,0.00569458,0.929146 beta-lactamase_2500_R81N,beta-lactamase_2500_81,TEM-1,beta-lactamase_2500,P62593,0.929195,NO,81,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.466,-2.825,1.359,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.361275,0.00499763,0.929195 kka2_1:2_H139P,kka2_1:2_139,Kka2,kka2_1:2,P00552,0.929198,NO,139,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-2.809,-4.177,1.368,,0.471,H,A,0.87,0.68,13.912,13.912,63.64,BBB,-2.22,0.295029,0.00734779,0.929198 beta-lactamase_F6I,beta-lactamase_6,TEM-1,beta-lactamase,P62593,0.929201,NO,6,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.847,-1.792,-0.055,,,,,,,1.276,,67.83,BHB,-2.076,0.221079,0.00261627,0.929201 beta-lactamase_G154Q,beta-lactamase_154,TEM-1,beta-lactamase,P62593,0.929201,NO,154,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.823,-4.083,3.26,5.40944,0.54,T,l,0.77,-0.56,2.283,,64.69,HOA,-1.635,0.221079,0.00180205,0.929201 beta-lactamase_0_D155I,beta-lactamase_0_155,TEM-1,beta-lactamase_0,P62593,0.929288,NO,155,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.889,-4.06,3.171,,0.049,,B,0.75,-0.9,16.833,16.833,64.69,OAB,-1.62267,0.0500837,0.00135315,0.929288 beta-lactamase_156_L218Q,beta-lactamase_156_218,TEM-1,beta-lactamase_156,P62593,0.929298,NO,218,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.391,-3.953,2.562,,,I,b,0.55,-0.53,17.202,17.202,74.48,OHH,-1.58867,0.111618,0.00618274,0.929298 beta-lactamase_0_L38Y,beta-lactamase_0_38,TEM-1,beta-lactamase_0,P62593,0.929326,NO,38,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.343,-2.956,1.613,,0.088,H,A,0.55,0.2,13.556,13.556,64.34,PHO,-1.78033,0.0500837,0.00373244,0.929326 beta-lactamase_0_A185T,beta-lactamase_0_185,TEM-1,beta-lactamase_0,P62593,0.929327,NO,185,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.406,-2.128,0.722,,,H,A,0.46,-1.02,1.203,,65.03,HHP,-1.84033,0.0500837,0.00467449,0.929327 beta-lactamase_2500_Y103F,beta-lactamase_2500_103,TEM-1,beta-lactamase_2500,P62593,0.92934,NO,103,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-1.33,-3.391,2.061,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.361275,0.00443048,0.92934 kka2_1:8_R147T,kka2_1:8_147,Kka2,kka2_1:8,P00552,0.929355,NO,147,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.123,-3.56,2.437,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.100394,0.00549168,0.929355 kka2_1:8_R147T,kka2_1:8_147,Kka2,kka2_1:8,P00552,0.929355,NO,147,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.123,-3.56,2.437,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.100394,0.00549168,0.929355 kka2_1:2_A9D,kka2_1:2_9,Kka2,kka2_1:2,P00552,0.929416,NO,9,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.079,-3.62,1.541,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.295029,0.00273264,0.929416 kka2_1:8_T85N,kka2_1:8_85,Kka2,kka2_1:8,P00552,0.929417,NO,85,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.165,-3.801,1.636,,0.576,E,B,0.22,1.39,22.154,22.154,71.59,HPA,-2.10133,0.100394,0.00634493,0.929417 kka2_1:8_T85N,kka2_1:8_85,Kka2,kka2_1:8,P00552,0.929417,NO,85,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.165,-3.801,1.636,,0.576,E,B,0.22,1.39,22.154,22.154,71.59,HPA,-2.10133,0.100394,0.00634493,0.929417 beta-lactamase_2500_R239V,beta-lactamase_2500_239,TEM-1,beta-lactamase_2500,P62593,0.929419,NO,239,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.361275,0.00213852,0.929419 beta-lactamase_D83Q,beta-lactamase_83,TEM-1,beta-lactamase,P62593,0.929421,NO,83,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.066,-3.681,2.615,5.40616,0.354,H,A,1.33,0.22,0.861,,48.95,HAH,-1.34733,0.221079,0.00205968,0.929421 kka2_1:4_M116R,kka2_1:4_116,Kka2,kka2_1:4,P00552,0.929453,NO,116,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-2.482,-4.144,1.662,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.168804,0.00745147,0.929453 beta-lactamase_2500_V106A,beta-lactamase_2500_106,TEM-1,beta-lactamase_2500,P62593,0.929465,NO,106,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.218,-3.084,1.866,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.361275,0.00304168,0.929465 beta-lactamase_0_L55P,beta-lactamase_0_55,TEM-1,beta-lactamase_0,P62593,0.929496,NO,55,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.86,-4.226,2.366,,0.372,E,A,0.55,-0.36,1.967,,63.99,HHA,-2.247,0.0500837,0.00403741,0.929496 kka2_1:1_I141V,kka2_1:1_141,Kka2,kka2_1:1,P00552,0.929521,NO,141,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.495,-1.912,0.417,,0.068,H,A,0.48,-0.01,7.546,7.546,92.05,BHA,-1.689,0.520039,0.00744745,0.929521 kka2_1:8_M148T,kka2_1:8_148,Kka2,kka2_1:8,P00552,0.929539,NO,148,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.847,-2.724,0.877,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.100394,0.00982664,0.929539 kka2_1:8_M148T,kka2_1:8_148,Kka2,kka2_1:8,P00552,0.929539,NO,148,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.847,-2.724,0.877,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.100394,0.00982664,0.929539 kka2_1:4_V75A,kka2_1:4_75,Kka2,kka2_1:4,P00552,0.929546,NO,75,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-2.06,-3.254,1.194,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.168804,0.00693733,0.929546 beta-lactamase_0_I54V,beta-lactamase_0_54,TEM-1,beta-lactamase_0,P62593,0.929551,NO,54,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-2.838,-2.687,-0.151,,0.669,E,B,0.48,-0.14,0.541,,73.78,BHH,-2.337,0.0500837,0.00403589,0.929551 kka2_1:2_E161C,kka2_1:2_161,Kka2,kka2_1:2,P00552,0.929568,NO,161,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.581,-5.043,3.462,,0.829,G,A,1.52,2.24,1.612,,92.05,AAB,-1.861,0.295029,0.00760103,0.929568 kka2_1:8_H106F,kka2_1:8_106,Kka2,kka2_1:8,P00552,0.929579,NO,106,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-3.13,-4.435,1.305,,1.065,,a,0.87,-0.95,15.956,15.956,71.59,PBH,-2.10433,0.100394,0.00730778,0.929579 kka2_1:8_H106F,kka2_1:8_106,Kka2,kka2_1:8,P00552,0.929579,NO,106,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-3.13,-4.435,1.305,,1.065,,a,0.87,-0.95,15.956,15.956,71.59,PBH,-2.10433,0.100394,0.00730778,0.929579 beta-lactamase_0_M184C,beta-lactamase_0_184,TEM-1,beta-lactamase_0,P62593,0.929581,NO,184,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.593,-4.787,3.194,,,H,A,0.55,-0.87,13.292,13.292,62.94,HHH,-1.41,0.0500837,0.00356019,0.929581 beta-lactamase_0_N274E,beta-lactamase_0_274,TEM-1,beta-lactamase_0,P62593,0.929581,NO,274,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.0500837,0.0110418,0.929581 kka2_1:8_A144G,kka2_1:8_144,Kka2,kka2_1:8,P00552,0.9296,NO,144,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.859,-3.076,2.217,,,H,A,1.04,0.21,1.118,,52.65,BHB,-1.72933,0.100394,0.00231095,0.9296 kka2_1:8_A144G,kka2_1:8_144,Kka2,kka2_1:8,P00552,0.9296,NO,144,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.859,-3.076,2.217,,,H,A,1.04,0.21,1.118,,52.65,BHB,-1.72933,0.100394,0.00231095,0.9296 beta-lactamase_625_L89Q,beta-lactamase_625_89,TEM-1,beta-lactamase_625,P62593,0.929616,NO,89,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.096,-4.086,2.99,,0.168,T,A,0.55,0.63,1.599,,64.34,PHO,-1.75767,0.213352,0.00207068,0.929616 beta-lactamase_0_P217L,beta-lactamase_0_217,TEM-1,beta-lactamase_0,P62593,0.929622,NO,217,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-2.062,-3.634,1.572,,0.496,I,A,0.52,-0.33,1.087,,74.48,OOH,-1.64333,0.0500837,0.00463211,0.929622 beta-lactamase_G90C,beta-lactamase_90,TEM-1,beta-lactamase,P62593,0.929657,NO,90,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-2.091,-5.167,3.076,5.51991,0.598,T,A,0.23,0.32,1.791,,77.62,HOB,-1.52633,0.221079,0.00490273,0.929657 beta-lactamase_T126Q,beta-lactamase_126,TEM-1,beta-lactamase,P62593,0.929675,NO,126,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.122,-3.945,2.823,4.82694,0.05,H,A,0.3,-0.05,1.14,,44.41,HPH,-1.60467,0.221079,0.00244552,0.929675 PSD95pdz3_G329S,PSD95pdz3_329,PSD95pdz3,PSD95pdz3,P31016,0.929676,NO,329,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.008,-2.842,1.834,4.7671,,,,,19.7075,,,,HOO,-1.16033,0.0758425,0.000974577,0.929676 WW_domain_Q200S,WW_domain_200,Yap65,WW_domain,P46937,0.929714,NO,200,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-1.599,-3.095,1.496,5.37476,,,,,,1.9,,70.04,HPA,-1.484,0.153962,0.00300397,0.929714 kka2_1:2_A65S,kka2_1:2_65,Kka2,kka2_1:2,P00552,0.929719,NO,65,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.744,-2.937,1.193,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.295029,0.00709258,0.929719 beta-lactamase_0_D155L,beta-lactamase_0_155,TEM-1,beta-lactamase_0,P62593,0.929731,NO,155,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.889,-3.807,2.918,,0.049,,B,0.75,-0.9,16.833,16.833,64.69,OAB,-1.62267,0.0500837,0.00135315,0.929731 kka2_1:8_L158K,kka2_1:8_158,Kka2,kka2_1:8,P00552,0.929763,NO,158,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.947,-3.896,1.949,,0.095,.,B,0.55,0.77,1.607,,63.64,AHA,-1.25333,0.100394,0.00529068,0.929763 kka2_1:8_L158K,kka2_1:8_158,Kka2,kka2_1:8,P00552,0.929763,NO,158,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.947,-3.896,1.949,,0.095,.,B,0.55,0.77,1.607,,63.64,AHA,-1.25333,0.100394,0.00529068,0.929763 PSD95pdz3_K393I,PSD95pdz3_393,PSD95pdz3,PSD95pdz3,P31016,0.929763,NO,393,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.416,-3.692,2.276,5.42682,,,,,22.0122,,,,HBO,-1.4265,0.0758425,0.000879298,0.929763 beta-lactamase_N173I,beta-lactamase_173,TEM-1,beta-lactamase,P62593,0.929808,NO,173,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-2.663,-4.172,1.509,7.02497,1.044,T,l,0.09,1.25,1.88,,77.62,OPA,-1.46633,0.221079,0.0033769,0.929808 kka2_1:4_P98S,kka2_1:4_98,Kka2,kka2_1:4,P00552,0.929808,NO,98,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.526,-2.565,1.039,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.168804,0.00622754,0.929808 beta-lactamase_0_S80C,beta-lactamase_0_80,TEM-1,beta-lactamase_0,P62593,0.929857,NO,80,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.029,-4.922,2.893,,0.192,H,A,0.27,0.46,12.403,12.403,77.62,HPB,-1.44567,0.0500837,0.00565569,0.929857 beta-lactamase_L219M,beta-lactamase_219,TEM-1,beta-lactamase,P62593,0.929879,NO,219,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.313,-3.006,1.693,5.74153,,I,A,0.84,-0.51,2.321,,74.48,HHB,-1.21533,0.221079,0.00664345,0.929879 kka2_1:4_D227Q,kka2_1:4_227,Kka2,kka2_1:4,P00552,0.929885,NO,227,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.758,-3.747,1.989,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.168804,0.00745029,0.929885 gb1_T244G,gb1_244,gb1,gb1,P06654,0.929938,NO,244,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.637,-3.275,1.638,,,,,,,0.202,,11.83,PPA,-1.92567,0.177985,0.00222755,0.929938 Pab1_N132M,Pab1_132,Pab1,Pab1,P04147,0.929946,NO,132,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-1.079,-4.522,3.443,,0.412,S,l,,0.9,,,,BPH,-1.067,0.175299,0.000347671,0.929946 beta-lactamase_0_R220Y,beta-lactamase_0_220,TEM-1,beta-lactamase_0,P62593,0.929974,NO,220,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-0.942,-4.188,3.246,,0.295,I,A,1.2,-0.76,21.573,21.573,74.48,HBP,-1.33633,0.0500837,0.00232421,0.929974 beta-lactamase_R59H,beta-lactamase_59,TEM-1,beta-lactamase,P62593,0.930021,NO,59,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.345,-4.424,3.079,5.49837,0.329,S,L,0.68,-0.09,1.806,,73.08,HBO,-2.24267,0.221079,0.00318082,0.930021 Pab1_L186T,Pab1_186,Pab1,Pab1,P04147,0.930026,NO,186,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.783,-3.267,1.484,,,,,,,,,,HHP,-1.56967,0.175299,0.00154968,0.930026 beta-lactamase_0_L205C,beta-lactamase_0_205,TEM-1,beta-lactamase_0,P62593,0.930033,NO,205,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.922,-4.692,3.77,,,H,A,0.55,-0.46,1.065,,42.31,PHH,-1.57767,0.0500837,0.00255802,0.930033 beta-lactamase_156_I125H,beta-lactamase_156_125,TEM-1,beta-lactamase_156,P62593,0.93006,NO,125,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.441,-4.965,3.524,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.111618,0.00383964,0.93006 beta-lactamase_2500_A200F,beta-lactamase_2500_200,TEM-1,beta-lactamase_2500,P62593,0.930065,NO,200,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.878,-4.397,2.519,,0.757,H,A,0.46,-0.19,0.436,,77.62,HHP,-2.001,0.361275,0.0060056,0.930065 beta-lactamase_2500_G236A,beta-lactamase_2500_236,TEM-1,beta-lactamase_2500,P62593,0.930081,NO,236,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.784,-2.29,1.506,,0.241,,b,0.29,-0.59,2.14,,64.69,HOO,-1.025,0.361275,0.00162372,0.930081 beta-lactamase_156_A268K,beta-lactamase_156_268,TEM-1,beta-lactamase_156,P62593,0.930113,NO,268,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.111618,0.0102525,0.930113 E1_Ubiquitin_H70L,E1_Ubiquitin_70,Uba1,E1_Ubiquitin,P0CG63,0.93015,NO,70,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-1.36,,,,0.05,E,B,0.61,-0.97,,,93.18,HBH,-1.146,0.18783,0.00206914,0.93015 beta-lactamase_K32C,beta-lactamase_32,TEM-1,beta-lactamase,P62593,0.930203,NO,32,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.984,-5.093,3.109,5.55842,0.563,H,A,1.82,0.34,1.754,,73.08,HBA,-2.04233,0.221079,0.00401283,0.930203 beta-lactamase_M153Q,beta-lactamase_153,TEM-1,beta-lactamase,P62593,0.930203,NO,153,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-3.193,-4.202,1.009,5.46509,0.14,T,A,1.07,-0.11,2.061,,77.62,PHO,-2.25767,0.221079,0.00509109,0.930203 beta-lactamase_M184F,beta-lactamase_184,TEM-1,beta-lactamase,P62593,0.930203,NO,184,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.593,-2.94,1.347,5.39575,,H,A,1.3,-0.87,2.893,,62.94,HHH,-1.41,0.221079,0.00356019,0.930203 beta-lactamase_Q274G,beta-lactamase_274,TEM-1,beta-lactamase,P62593,0.930203,NO,274,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.082,-3.338,1.256,5.6671,0.066,H,A,0.11,-0.27,2.354,,64.69,BPH,-1.931,0.221079,0.0110418,0.930203 beta-lactamase_S2P,beta-lactamase_2,TEM-1,beta-lactamase,P62593,0.930203,NO,2,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.942,-2.181,0.239,,,,,,,2.36,,65.38,HPH,-2.02767,0.221079,0.00227352,0.930203 kka2_1:1_S104T,kka2_1:1_104,Kka2,kka2_1:1,P00552,0.930207,NO,104,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.436,-2.284,0.848,,0.536,T,A,0.27,-1.11,5.49,,63.64,HPP,-1.91433,0.520039,0.00555207,0.930207 kka2_1:8_D183A,kka2_1:8_183,Kka2,kka2_1:8,P00552,0.93021,NO,183,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.204,-3.349,2.145,,0.518,.,b,0.75,0.25,0.347,,52.27,AAH,-1.40533,0.100394,0.00426304,0.93021 kka2_1:8_D183A,kka2_1:8_183,Kka2,kka2_1:8,P00552,0.93021,NO,183,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.204,-3.349,2.145,,0.518,.,b,0.75,0.25,0.347,,52.27,AAH,-1.40533,0.100394,0.00426304,0.93021 beta-lactamase_0_G114R,beta-lactamase_0_114,TEM-1,beta-lactamase_0,P62593,0.930217,NO,114,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.094,-2.891,1.797,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.0500837,0.00224919,0.930217 Pab1_D138E,Pab1_138,Pab1,Pab1,P04147,0.930298,NO,138,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.128,-1.926,0.798,,0.427,,B,,-0.03,,,,HAP,-1.13967,0.175299,0.000567877,0.930298 beta-lactamase_2500_G154N,beta-lactamase_2500_154,TEM-1,beta-lactamase_2500,P62593,0.930323,NO,154,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.823,-3.507,2.684,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.361275,0.00180205,0.930323 beta-lactamase_M268A,beta-lactamase_268,TEM-1,beta-lactamase,P62593,0.93035,NO,268,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-2.023,-2.456,0.433,5.4797,0.471,H,A,0.09,0.3,1.071,,65.73,PHA,-2.16233,0.221079,0.0102525,0.93035 kka2_1:2_A65F,kka2_1:2_65,Kka2,kka2_1:2,P00552,0.930366,NO,65,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.744,-4.347,2.603,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.295029,0.00709258,0.930366 beta-lactamase_39_G39C,beta-lactamase_39_39,TEM-1,beta-lactamase_39,P62593,0.930389,NO,39,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.864,-5.191,3.327,,0.701,T,L,0.29,0.47,1.454,,77.62,HOH,-1.53633,0.0495842,0.00487611,0.930389 beta-lactamase_2500_I245L,beta-lactamase_2500_245,TEM-1,beta-lactamase_2500,P62593,0.930428,NO,245,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.361275,0.00391032,0.930428 beta-lactamase_R238P,beta-lactamase_238,TEM-1,beta-lactamase,P62593,0.930428,NO,238,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.002,-4.081,2.079,5.87663,0.564,T,L,0.45,1.09,4.195,,72.73,ABO,-1.62633,0.221079,0.00743256,0.930428 kka2_1:8_L241K,kka2_1:8_241,Kka2,kka2_1:8,P00552,0.930433,NO,241,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.158,-3.87,2.712,,0.08,H,A,1.59,-0.82,1.136,,63.26,HHH,-1.58533,0.100394,0.0117299,0.930433 kka2_1:8_L241K,kka2_1:8_241,Kka2,kka2_1:8,P00552,0.930433,NO,241,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.158,-3.87,2.712,,0.08,H,A,1.59,-0.82,1.136,,63.26,HHH,-1.58533,0.100394,0.0117299,0.930433 beta-lactamase_0_P172F,beta-lactamase_0_172,TEM-1,beta-lactamase_0,P62593,0.930461,NO,172,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.998,-4.371,3.373,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.0500837,0.00312594,0.930461 PSD95pdz3_A390Y,PSD95pdz3_390,PSD95pdz3,PSD95pdz3,P31016,0.930461,NO,390,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.307,-3.844,2.537,5.03823,,,,,12.46,,,,HHP,-1.54467,0.0758425,0.00104603,0.930461 kka2_1:1_Y218D,kka2_1:1_218,Kka2,kka2_1:1,P00552,0.930462,NO,218,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-1.438,-3.939,2.501,,0.122,H,A,1.25,-0.69,3.059,,56.06,BHP,-1.17533,0.520039,0.0126098,0.930462 kka2_1:2_E111L,kka2_1:2_111,Kka2,kka2_1:2,P00552,0.930492,NO,111,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.28,-3.101,0.821,,0.155,H,A,1.52,-1.14,2.792,,65.53,HAB,-2.27833,0.295029,0.00746789,0.930492 Pab1_I183S,Pab1_183,Pab1,Pab1,P04147,0.930492,NO,183,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.302,-3.481,2.179,,0.308,T,B,1,1.08,1.29,,75.56,HHA,-1.27167,0.175299,0.000574345,0.930492 PSD95pdz3_Y392R,PSD95pdz3_392,PSD95pdz3,PSD95pdz3,P31016,0.930492,NO,392,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-1.437,-3.615,2.178,5.20337,,,,,11.725,,,,PHB,-1.51733,0.0758425,0.000935211,0.930492 kka2_1:4_E231Q,kka2_1:4_231,Kka2,kka2_1:4,P00552,0.930519,NO,231,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.002,-3.771,1.769,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.168804,0.00732383,0.930519 beta-lactamase_0_F64R,beta-lactamase_0_64,TEM-1,beta-lactamase_0,P62593,0.930563,NO,64,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-0.841,-4.158,3.317,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.0500837,0.000947691,0.930563 kka2_1:2_R145N,kka2_1:2_145,Kka2,kka2_1:2,P00552,0.930598,NO,145,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.804,-3.787,1.983,,0.346,H,A,1.2,1.23,7.961,,63.64,HBP,-1.88033,0.295029,0.00846663,0.930598 kka2_1:8_D227M,kka2_1:8_227,Kka2,kka2_1:8,P00552,0.930636,NO,227,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.758,-4.662,2.904,,0.128,H,A,0.75,-0.63,0.281,,56.06,BAH,-1.43067,0.100394,0.00745029,0.930636 kka2_1:8_D227M,kka2_1:8_227,Kka2,kka2_1:8,P00552,0.930636,NO,227,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.758,-4.662,2.904,,0.128,H,A,0.75,-0.63,0.281,,56.06,BAH,-1.43067,0.100394,0.00745029,0.930636 beta-lactamase_0_S241W,beta-lactamase_0_241,TEM-1,beta-lactamase_0,P62593,0.930675,NO,241,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.0500837,0.00452736,0.930675 beta-lactamase_625_R242T,beta-lactamase_625_242,TEM-1,beta-lactamase_625,P62593,0.930701,NO,242,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.213352,0.00452879,0.930701 beta-lactamase_0_L28A,beta-lactamase_0_28,TEM-1,beta-lactamase_0,P62593,0.930705,NO,28,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.579,-2.126,0.547,,0.277,H,A,0.55,-0.16,9.35,9.35,93.01,PHH,-2.11333,0.0500837,0.00359321,0.930705 beta-lactamase_0_A282L,beta-lactamase_0_282,TEM-1,beta-lactamase_0,P62593,0.930742,NO,282,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.586,-3.183,1.597,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.0500837,0.0449821,0.930742 beta-lactamase_2500_A77T,beta-lactamase_2500_77,TEM-1,beta-lactamase_2500,P62593,0.930753,NO,77,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.234,-2.687,1.453,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.361275,0.00282362,0.930753 beta-lactamase_0_R91P,beta-lactamase_0_91,TEM-1,beta-lactamase_0,P62593,0.930757,NO,91,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.392,-3.876,2.484,,0.444,,B,1.2,0.96,4.557,,50.35,OBB,-1.73367,0.0500837,0.00380226,0.930757 beta-lactamase_39_A225T,beta-lactamase_39_225,TEM-1,beta-lactamase_39,P62593,0.930779,NO,225,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.845,-2.966,1.121,,1,T,B,0.46,-0.38,9.874,9.874,74.48,OHO,-1.39967,0.0495842,0.00465057,0.930779 kka2_1:1_M1R,kka2_1:1_1,Kka2,kka2_1:1,P00552,0.930865,NO,1,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.787,-3.648,1.861,,,,,,,3.101,,62.12,NAHH,-1.787,0.520039,0.00251939,0.930865 kka2_1:4_R38H,kka2_1:4_38,Kka2,kka2_1:4,P00552,0.930992,NO,38,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.207,-4.545,3.338,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.168804,0.00372499,0.930992 WW_domain_Q186S,WW_domain_186,Yap65,WW_domain,P46937,0.93103,NO,186,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-1.358,-2.938,1.58,4.88854,,,,,,,,,OPB,-1.207,0.153962,0.00161546,0.93103 beta-lactamase_625_D174G,beta-lactamase_625_174,TEM-1,beta-lactamase_625,P62593,0.931044,NO,174,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.738,-3.133,2.395,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.213352,0.00125633,0.931044 beta-lactamase_E145P,beta-lactamase_145,TEM-1,beta-lactamase,P62593,0.931053,NO,145,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.357,-3.914,1.557,5.38104,0.545,H,A,0.52,0.79,2.124,,77.62,BAH,-2.069,0.221079,0.00553285,0.931053 PSD95pdz3_A390H,PSD95pdz3_390,PSD95pdz3,PSD95pdz3,P31016,0.931065,NO,390,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.307,-4.362,3.055,5.03823,,,,,12.46,,,,HHP,-1.54467,0.0758425,0.00104603,0.931065 kka2_1:8_D134R,kka2_1:8_134,Kka2,kka2_1:8,P00552,0.931072,NO,134,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.969,-3.942,2.973,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.100394,0.00270812,0.931072 kka2_1:8_D134R,kka2_1:8_134,Kka2,kka2_1:8,P00552,0.931072,NO,134,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.969,-3.942,2.973,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.100394,0.00270812,0.931072 PSD95pdz3_N369Y,PSD95pdz3_369,PSD95pdz3,PSD95pdz3,P31016,0.931078,NO,369,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-1.572,-3.939,2.367,5.91569,,,,,24.1262,0.44,,87.71,BPH,-1.487,0.0758425,0.000608412,0.931078 beta-lactamase_2500_E169C,beta-lactamase_2500_169,TEM-1,beta-lactamase_2500,P62593,0.931084,NO,169,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.23,-5.088,3.858,,0.337,,A,1.04,1,1.806,,73.08,PAH,-1.16533,0.361275,0.00400994,0.931084 beta-lactamase_2500_L74V,beta-lactamase_2500_74,TEM-1,beta-lactamase_2500,P62593,0.931121,NO,74,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.296,-2.972,1.676,,,H,A,0.55,-0.91,0.746,,50,HHO,-1.34933,0.361275,0.00493255,0.931121 beta-lactamase_2500_E238V,beta-lactamase_2500_238,TEM-1,beta-lactamase_2500,P62593,0.931162,NO,238,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.361275,0.00743256,0.931162 beta-lactamase_0_V72D,beta-lactamase_0_72,TEM-1,beta-lactamase_0,P62593,0.931168,NO,72,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.658,-3.942,2.284,,,H,A,0.44,-1.03,2.964,,65.73,BHH,-1.32167,0.0500837,0.00501194,0.931168 kka2_1:4_G21C,kka2_1:4_21,Kka2,kka2_1:4,P00552,0.931172,NO,21,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.368,-5.139,3.771,,0.586,T,l,0.75,-0.75,3.075,,71.59,HOH,-2.10167,0.168804,0.00709648,0.931172 PSD95pdz3_L367T,PSD95pdz3_367,PSD95pdz3,PSD95pdz3,P31016,0.93119,NO,367,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.347,-3.103,1.756,5.47696,,,,,17.0063,,,,AHB,-1.39767,0.0758425,0.000466436,0.93119 kka2_1:2_D156Y,kka2_1:2_156,Kka2,kka2_1:2,P00552,0.931202,NO,156,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.696,-4.451,2.755,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.295029,0.00926998,0.931202 beta-lactamase_0_G265N,beta-lactamase_0_265,TEM-1,beta-lactamase_0,P62593,0.931209,NO,265,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.0500837,0.00811926,0.931209 beta-lactamase_39_R202P,beta-lactamase_39_202,TEM-1,beta-lactamase_39,P62593,0.931215,NO,202,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.292,-3.859,2.567,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.0495842,0.00321899,0.931215 kka2_1:8_P98S,kka2_1:8_98,Kka2,kka2_1:8,P00552,0.931224,NO,98,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.526,-2.565,1.039,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.100394,0.00622754,0.931224 kka2_1:8_P98S,kka2_1:8_98,Kka2,kka2_1:8,P00552,0.931224,NO,98,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.526,-2.565,1.039,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.100394,0.00622754,0.931224 beta-lactamase_2500_P172C,beta-lactamase_2500_172,TEM-1,beta-lactamase_2500,P62593,0.931227,NO,172,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.998,-4.977,3.979,,0.639,T,b,0.52,0.24,4.99,,74.48,HOP,-2.03067,0.361275,0.00312594,0.931227 beta-lactamase_0_D231L,beta-lactamase_0_231,TEM-1,beta-lactamase_0,P62593,0.931236,NO,231,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.816,-3.806,2.99,,,E,B,0.75,-1.06,4.975,,65.38,HAB,-0.994,0.0500837,0.00107395,0.931236 kka2_1:8_W24G,kka2_1:8_24,Kka2,kka2_1:8,P00552,0.931245,NO,24,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-1.779,-3.736,1.957,,0.477,E,B,1.51,-0.21,2.503,,56.06,AHH,-2.24467,0.100394,0.00631564,0.931245 kka2_1:8_W24G,kka2_1:8_24,Kka2,kka2_1:8,P00552,0.931245,NO,24,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-1.779,-3.736,1.957,,0.477,E,B,1.51,-0.21,2.503,,56.06,AHH,-2.24467,0.100394,0.00631564,0.931245 beta-lactamase_L74M,beta-lactamase_74,TEM-1,beta-lactamase,P62593,0.931289,NO,74,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.296,-2.987,1.691,5.50288,,H,A,1.75,-0.91,1.581,,50,HHO,-1.34933,0.221079,0.00493255,0.931289 beta-lactamase_2500_E26F,beta-lactamase_2500_26,TEM-1,beta-lactamase_2500,P62593,0.931307,NO,26,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.454,-4.297,1.843,,0.54,H,A,1.04,0.98,0.49,,93.01,OAP,-1.96167,0.361275,0.00297948,0.931307 beta-lactamase_2500_I280V,beta-lactamase_2500_280,TEM-1,beta-lactamase_2500,P62593,0.931327,NO,280,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.361275,0.0530888,0.931327 Pab1_N132P,Pab1_132,Pab1,Pab1,P04147,0.931378,NO,132,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-1.079,-3.697,2.618,,0.412,S,l,,0.9,,,,BPH,-1.067,0.175299,0.000347671,0.931378 beta-lactamase_0_N274Y,beta-lactamase_0_274,TEM-1,beta-lactamase_0,P62593,0.931387,NO,274,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.0500837,0.0110418,0.931387 beta-lactamase_I206G,beta-lactamase_206,TEM-1,beta-lactamase,P62593,0.9314,NO,206,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-2.429,-2.667,0.238,5.3727,0.173,H,A,1,-0.34,2.061,,77.62,HHA,-1.805,0.221079,0.00528934,0.9314 kka2_1:4_A137S,kka2_1:4_137,Kka2,kka2_1:4,P00552,0.931408,NO,137,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.156,-2.895,0.739,,0.029,H,A,0.46,0.34,2.227,,63.26,PHB,-2.559,0.168804,0.00515054,0.931408 beta-lactamase_156_L218H,beta-lactamase_156_218,TEM-1,beta-lactamase_156,P62593,0.931419,NO,218,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.391,-4.744,3.353,,,I,b,0.55,-0.53,17.202,17.202,74.48,OHH,-1.58867,0.111618,0.00618274,0.931419 kka2_1:2_Q27E,kka2_1:2_27,Kka2,kka2_1:2,P00552,0.931428,NO,27,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-1.659,-2.681,1.022,,0.608,.,A,0.64,0.71,0.521,,65.53,PPP,-1.90733,0.295029,0.00595365,0.931428 beta-lactamase_2500_L284T,beta-lactamase_2500_284,TEM-1,beta-lactamase_2500,P62593,0.93144,NO,284,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.361275,0.0686156,0.93144 Pab1_A185F,Pab1_185,Pab1,Pab1,P04147,0.931451,NO,185,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.702,-4.119,2.417,,,,,,,1.756,,63.26,AHH,-1.66167,0.175299,0.00144499,0.931451 beta-lactamase_2500_H110Q,beta-lactamase_2500_110,TEM-1,beta-lactamase_2500,P62593,0.931476,NO,110,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-1.706,-2.734,1.028,,0.341,G,a,0.17,1.08,31.31,31.31,64.69,BBH,-1.73333,0.361275,0.00441499,0.931476 kka2_1:8_A71D,kka2_1:8_71,Kka2,kka2_1:8,P00552,0.931486,NO,71,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.824,-3.702,1.878,,0.553,H,A,0.46,0.08,18.64,18.64,64.39,HHP,-1.74033,0.100394,0.00727707,0.931486 kka2_1:8_A71D,kka2_1:8_71,Kka2,kka2_1:8,P00552,0.931486,NO,71,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.824,-3.702,1.878,,0.553,H,A,0.46,0.08,18.64,18.64,64.39,HHP,-1.74033,0.100394,0.00727707,0.931486 beta-lactamase_39_D33G,beta-lactamase_39_33,TEM-1,beta-lactamase_39,P62593,0.931487,NO,33,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.321,-3.465,1.144,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.0495842,0.00435556,0.931487 beta-lactamase_39_V101G,beta-lactamase_39_101,TEM-1,beta-lactamase_39,P62593,0.931497,NO,101,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.295,-3.721,2.426,,0.342,,B,0.44,0,2.96,,73.08,HHA,-1.54367,0.0495842,0.00374492,0.931497 kka2_1:8_L158Y,kka2_1:8_158,Kka2,kka2_1:8,P00552,0.931501,NO,158,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.947,-3.398,1.451,,0.095,.,B,0.55,0.77,1.607,,63.64,AHA,-1.25333,0.100394,0.00529068,0.931501 kka2_1:8_L158Y,kka2_1:8_158,Kka2,kka2_1:8,P00552,0.931501,NO,158,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.947,-3.398,1.451,,0.095,.,B,0.55,0.77,1.607,,63.64,AHA,-1.25333,0.100394,0.00529068,0.931501 beta-lactamase_156_H110I,beta-lactamase_156_110,TEM-1,beta-lactamase_156,P62593,0.931513,NO,110,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-1.706,-4.048,2.342,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.111618,0.00441499,0.931513 beta-lactamase_39_T131I,beta-lactamase_39_131,TEM-1,beta-lactamase_39,P62593,0.931554,NO,131,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.328,-3.758,2.43,,,H,A,0.22,-0.69,3.306,,67.48,PPH,-1.00867,0.0495842,0.00345886,0.931554 beta-lactamase_2500_D113F,beta-lactamase_2500_113,TEM-1,beta-lactamase_2500,P62593,0.93158,NO,113,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.829,-4.448,2.619,,0.665,T,A,0.75,0.91,21.104,21.104,73.08,PAO,-1.703,0.361275,0.00474112,0.93158 kka2_1:8_A108S,kka2_1:8_108,Kka2,kka2_1:8,P00552,0.931589,NO,108,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.061,-2.146,0.085,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.100394,0.00751209,0.931589 kka2_1:8_A108S,kka2_1:8_108,Kka2,kka2_1:8,P00552,0.931589,NO,108,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.061,-2.146,0.085,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.100394,0.00751209,0.931589 beta-lactamase_0_M67K,beta-lactamase_0_67,TEM-1,beta-lactamase_0,P62593,0.931594,NO,67,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-2.231,-3.7,1.469,,0.006,G,P,0.55,-0.81,24.165,24.165,65.03,HHP,-1.502,0.0500837,0.00409753,0.931594 beta-lactamase_2500_A183R,beta-lactamase_2500_183,TEM-1,beta-lactamase_2500,P62593,0.931594,NO,183,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.231,-3.825,2.594,,0.155,H,A,0.46,-0.91,12.189,,77.62,HHH,-1.53367,0.361275,0.00296631,0.931594 beta-lactamase_156_A124L,beta-lactamase_156_124,TEM-1,beta-lactamase_156,P62593,0.931609,NO,124,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.181,-3.172,1.991,,,H,A,0.46,-0.9,2.027,,64.34,HHH,-1.152,0.111618,0.00481399,0.931609 beta-lactamase_0_T158K,beta-lactamase_0_158,TEM-1,beta-lactamase_0,P62593,0.931615,NO,158,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.116,-3.466,2.35,,0.036,,B,0.22,-0.85,1.041,,69.58,HPB,-1.269,0.0500837,0.00341825,0.931615 beta-lactamase_156_T178G,beta-lactamase_156_178,TEM-1,beta-lactamase_156,P62593,0.931617,NO,178,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-0.791,-3.358,2.567,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.111618,0.000684366,0.931617 beta-lactamase_A215G,beta-lactamase_215,TEM-1,beta-lactamase,P62593,0.931654,NO,215,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.503,-1.579,0.076,4.82164,,,a,0.75,-0.93,3.583,,74.48,HHO,-1.42633,0.221079,0.00544007,0.931654 beta-lactamase_156_R63D,beta-lactamase_156_63,TEM-1,beta-lactamase_156,P62593,0.93166,NO,63,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-0.943,-3.762,2.819,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.111618,0.00126938,0.93166 beta-lactamase_0_T147Y,beta-lactamase_0_147,TEM-1,beta-lactamase_0,P62593,0.93167,NO,147,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.149,-4.243,3.094,,0.281,H,A,0.22,-0.68,3.487,,64.34,HPH,-1.456,0.0500837,0.00226017,0.93167 beta-lactamase_0_A235P,beta-lactamase_0_235,TEM-1,beta-lactamase_0,P62593,0.931673,NO,235,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.266,-3.821,2.555,,0.32,E,B,0.46,-0.86,2.261,,50,OHO,-0.89,0.0500837,0.00493474,0.931673 beta-lactamase_2500_L111C,beta-lactamase_2500_111,TEM-1,beta-lactamase_2500,P62593,0.931705,NO,111,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.76,-4.796,3.036,,0.328,T,A,0.55,0.93,1.966,,64.34,BHP,-1.884,0.361275,0.00480671,0.931705 beta-lactamase_A16P,beta-lactamase_16,TEM-1,beta-lactamase,P62593,0.931707,NO,16,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,,-2.766,0.831,,,,,,,,,,HHH,,0.221079,0.00245392,0.931707 beta-lactamase_L28T,beta-lactamase_28,TEM-1,beta-lactamase,P62593,0.931707,NO,28,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.579,-3.444,1.865,5.42969,0.277,H,A,0.07,-0.16,19.748,19.748,93.01,PHH,-2.11333,0.221079,0.00359321,0.931707 beta-lactamase_39_G216V,beta-lactamase_39_216,TEM-1,beta-lactamase_39,P62593,0.931734,NO,216,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.477,-3.793,2.316,,0.437,I,A,0.29,-0.58,0.834,,74.48,HOO,-1.68067,0.0495842,0.00639568,0.931734 beta-lactamase_2500_P255F,beta-lactamase_2500_255,TEM-1,beta-lactamase_2500,P62593,0.931737,NO,255,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.361275,0.00499612,0.931737 beta-lactamase_2500_T179S,beta-lactamase_2500_179,TEM-1,beta-lactamase_2500,P62593,0.931766,NO,179,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.085,-2.228,1.143,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.361275,0.00226045,0.931766 beta-lactamase_M268V,beta-lactamase_268,TEM-1,beta-lactamase,P62593,0.931778,NO,268,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-2.023,-2.627,0.604,5.4797,0.471,H,A,0.09,0.3,1.071,,65.73,PHA,-2.16233,0.221079,0.0102525,0.931778 beta-lactamase_H5P,beta-lactamase_5,TEM-1,beta-lactamase,P62593,0.931783,NO,5,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-2.698,-2.83,0.132,,,,,,,1.865,,72.73,PBH,-2.36967,0.221079,0.00292712,0.931783 kka2_1:2_Y257F,kka2_1:2_257,Kka2,kka2_1:2,P00552,0.931792,NO,257,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-1.064,-1.664,0.6,,0.022,H,A,0.21,-0.88,0.833,,52.65,HHB,-1.39333,0.295029,0.0148191,0.931792 beta-lactamase_L282T,beta-lactamase_282,TEM-1,beta-lactamase,P62593,0.931794,NO,282,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.586,-3.527,1.941,5.16743,0.007,H,A,1.07,0.34,31.31,31.31,63.99,PHH,-1.82367,0.221079,0.0449821,0.931794 beta-lactamase_0_L55Y,beta-lactamase_0_55,TEM-1,beta-lactamase_0,P62593,0.93186,NO,55,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.86,-3.812,1.952,,0.372,E,A,0.55,-0.36,1.967,,63.99,HHA,-2.247,0.0500837,0.00403741,0.93186 gb1_F256M,gb1_256,gb1,gb1,P06654,0.931915,NO,256,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.241,-4.032,2.791,,,,,,,,,,HHB,-2.04767,0.177985,0.00435993,0.931915 E1_Ubiquitin_Q40H,E1_Ubiquitin_40,Uba1,E1_Ubiquitin,P0CG63,0.931919,NO,40,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-1.48,-2.479,0.999,,0.387,G,A,,0.03,,,,OPP,-1.365,0.18783,0.0037961,0.931919 beta-lactamase_0_T27Q,beta-lactamase_0_27,TEM-1,beta-lactamase_0,P62593,0.931926,NO,27,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.905,-3.929,2.024,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.0500837,0.00306559,0.931926 beta-lactamase_P25I,beta-lactamase_25,TEM-1,beta-lactamase,P62593,0.931928,NO,25,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.526,-4.029,2.503,5.6134,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.221079,0.00347571,0.931928 beta-lactamase_0_I140K,beta-lactamase_0_140,TEM-1,beta-lactamase_0,P62593,0.931936,NO,140,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.733,-3.879,2.146,,0.128,H,A,0.48,0.41,4.714,,73.08,PHO,-1.48733,0.0500837,0.00597777,0.931936 kka2_1:8_D90N,kka2_1:8_90,Kka2,kka2_1:8,P00552,0.931953,NO,90,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.459,-2.125,-0.334,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.100394,0.00583842,0.931953 kka2_1:8_D90N,kka2_1:8_90,Kka2,kka2_1:8,P00552,0.931953,NO,90,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.459,-2.125,-0.334,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.100394,0.00583842,0.931953 beta-lactamase_2500_S122M,beta-lactamase_2500_122,TEM-1,beta-lactamase_2500,P62593,0.93196,NO,122,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.406,-4.704,2.298,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.361275,0.00497825,0.93196 beta-lactamase_R81L,beta-lactamase_81,TEM-1,beta-lactamase,P62593,0.931965,NO,81,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.466,-2.766,1.3,5.12166,0.218,H,A,0.68,1.66,1.236,,50,PBH,-1.60667,0.221079,0.00499763,0.931965 kka2_1:4_P179R,kka2_1:4_179,Kka2,kka2_1:4,P00552,0.931975,NO,179,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.974,-4.006,3.032,,0.113,,B,0.52,0.69,10.913,10.913,56.06,HOA,-2.19867,0.168804,0.00298346,0.931975 beta-lactamase_0_D161W,beta-lactamase_0_161,TEM-1,beta-lactamase_0,P62593,0.931985,NO,161,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.891,-5.546,4.655,,0.341,,A,0.75,-0.52,0.795,,61.19,HAB,-0.961333,0.0500837,0.000897697,0.931985 beta-lactamase_0_T138P,beta-lactamase_0_138,TEM-1,beta-lactamase_0,P62593,0.931997,NO,138,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.506,-3.038,0.532,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.0500837,0.00487868,0.931997 beta-lactamase_156_T126F,beta-lactamase_156_126,TEM-1,beta-lactamase_156,P62593,0.932053,NO,126,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.122,-4.199,3.077,,0.05,H,A,0.22,-0.05,1.14,,44.41,HPH,-1.60467,0.111618,0.00244552,0.932053 beta-lactamase_625_T107I,beta-lactamase_625_107,TEM-1,beta-lactamase_625,P62593,0.932064,NO,107,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.117,-3.664,2.547,,,G,A,0.22,-0.06,3.676,,67.83,HPA,-1.265,0.213352,0.00239347,0.932064 beta-lactamase_F17L,beta-lactamase_17,TEM-1,beta-lactamase,P62593,0.932065,NO,17,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-2.337,-2.06,-0.277,,,,,,,2.192,,67.83,HHO,-2.17733,0.221079,0.00216499,0.932065 kka2_1:1_D33L,kka2_1:1_33,Kka2,kka2_1:1,P00552,0.932128,NO,33,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.186,-3.734,1.548,,0.561,S,A,0.75,3.35,2.568,,71.59,PAH,-1.306,0.520039,0.00633568,0.932128 beta-lactamase_E108L,beta-lactamase_108,TEM-1,beta-lactamase,P62593,0.932158,NO,108,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.46,-3.653,2.193,5.52079,0.572,G,A,0.52,1.87,1.973,,72.73,PAB,-1.437,0.221079,0.00413372,0.932158 beta-lactamase_0_N50C,beta-lactamase_0_50,TEM-1,beta-lactamase_0,P62593,0.93216,NO,50,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-2.979,-5.044,2.065,,0.912,T,A,0.61,1.24,9.874,9.874,77.62,HPP,-2.134,0.0500837,0.0047211,0.93216 kka2_1:4_A25S,kka2_1:4_25,Kka2,kka2_1:4,P00552,0.932163,NO,25,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.496,-2.739,0.243,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.168804,0.00595636,0.932163 beta-lactamase_0_F149V,beta-lactamase_0_149,TEM-1,beta-lactamase_0,P62593,0.932164,NO,149,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.299,-3.45,2.151,,0.195,H,A,0.58,0.11,3.518,,63.99,HHH,-1.46067,0.0500837,0.00418462,0.932164 beta-lactamase_625_S201Y,beta-lactamase_625_201,TEM-1,beta-lactamase_625,P62593,0.932212,NO,201,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.183,-4.222,3.039,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.213352,0.00198815,0.932212 PSD95pdz3_G322L,PSD95pdz3_322,PSD95pdz3,PSD95pdz3,P31016,0.932231,NO,322,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.008,-3.49,2.482,5.24791,,,,,16.3275,,,,POH,-1.24867,0.0758425,0.00105821,0.932231 Pab1_A185Y,Pab1_185,Pab1,Pab1,P04147,0.932248,NO,185,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.702,-4.142,2.44,,,,,,,1.756,,63.26,AHH,-1.66167,0.175299,0.00144499,0.932248 WW_domain_S184L,WW_domain_184,Yap65,WW_domain,P46937,0.932269,NO,184,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.363,-3.129,1.766,5.06696,,,,,,,,,PPO,-1.39133,0.153962,0.00231095,0.932269 beta-lactamase_156_A230Y,beta-lactamase_156_230,TEM-1,beta-lactamase_156,P62593,0.932301,NO,230,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.154,-4.312,3.158,,0.01,E,B,0.46,-1.17,2.179,,50,HHA,-1.079,0.111618,0.00516841,0.932301 beta-lactamase_0_E46S,beta-lactamase_0_46,TEM-1,beta-lactamase_0,P62593,0.932344,NO,46,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.94,-3.545,1.605,,0.021,E,B,1.04,0.14,30.306,30.306,59.44,HAH,-2.079,0.0500837,0.00427568,0.932344 beta-lactamase_0_G253A,beta-lactamase_0_253,TEM-1,beta-lactamase_0,P62593,0.932357,NO,253,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.0500837,0.00786358,0.932357 kka2_1:4_P98Q,kka2_1:4_98,Kka2,kka2_1:4,P00552,0.93237,NO,98,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.526,-3.169,1.643,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.168804,0.00622754,0.93237 Pab1_M189K,Pab1_189,Pab1,Pab1,P04147,0.932387,NO,189,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.406,-3.274,1.868,,0.631,E,b,,2.81,,,,OHH,-1.18,0.175299,0.000278756,0.932387 beta-lactamase_39_E62C,beta-lactamase_39_62,TEM-1,beta-lactamase_39,P62593,0.932396,NO,62,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.193,-5.228,4.035,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.0495842,0.00264802,0.932396 beta-lactamase_2500_G39T,beta-lactamase_2500_39,TEM-1,beta-lactamase_2500,P62593,0.932425,NO,39,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.864,-2.931,1.067,,0.701,T,L,0.29,0.47,29.926,29.926,77.62,HOH,-1.53633,0.361275,0.00487611,0.932425 beta-lactamase_39_D113M,beta-lactamase_39_113,TEM-1,beta-lactamase_39,P62593,0.932433,NO,113,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.829,-4.826,2.997,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.0495842,0.00474112,0.932433 beta-lactamase_625_A235N,beta-lactamase_625_235,TEM-1,beta-lactamase_625,P62593,0.932499,NO,235,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.266,-3.746,2.48,,0.32,E,B,0.46,-0.86,0.281,,50,OHO,-0.89,0.213352,0.00493474,0.932499 beta-lactamase_0_M66P,beta-lactamase_0_66,TEM-1,beta-lactamase_0,P62593,0.932503,NO,66,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.362,-4.047,2.685,,0.013,,A,0.55,-0.7,1.204,,73.08,OHH,-1.49567,0.0500837,0.00412876,0.932503 beta-lactamase_39_E62V,beta-lactamase_39_62,TEM-1,beta-lactamase_39,P62593,0.932537,NO,62,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.193,-3.636,2.443,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.0495842,0.00264802,0.932537 beta-lactamase_2500_L219V,beta-lactamase_2500_219,TEM-1,beta-lactamase_2500,P62593,0.93256,NO,219,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.313,-2.847,1.534,,,I,A,0.55,-0.51,35.994,35.994,74.48,HHB,-1.21533,0.361275,0.00664345,0.93256 beta-lactamase_39_D48M,beta-lactamase_39_48,TEM-1,beta-lactamase_39,P62593,0.932564,NO,48,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.101,-4.896,3.795,,0.189,E,B,0.75,0.21,0.735,,50.35,HAH,-1.62467,0.0495842,0.0027273,0.932564 beta-lactamase_R41S,beta-lactamase_41,TEM-1,beta-lactamase,P62593,0.932565,NO,41,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-0.942,-2.526,1.584,5.69185,0.321,E,B,0.91,-0.07,4.357,,65.03,HBH,-1.30267,0.221079,0.00123327,0.932565 kka2_1:1_V83Y,kka2_1:1_83,Kka2,kka2_1:1,P00552,0.932612,NO,83,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-2.567,-3.301,0.734,,0.358,E,B,0.44,0.53,5.931,,71.59,AHH,-2.264,0.520039,0.00650486,0.932612 Pab1_I157T,Pab1_157,Pab1,Pab1,P04147,0.932644,NO,157,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.623,-3.179,1.556,,,,,,,1.439,,79.72,BHH,-1.28667,0.175299,0.0018103,0.932644 beta-lactamase_D99H,beta-lactamase_99,TEM-1,beta-lactamase,P62593,0.932647,NO,99,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.191,-3.065,1.874,5.66081,0.402,G,A,0.23,0.36,1.318,,64.69,PAH,-1.794,0.221079,0.00305446,0.932647 beta-lactamase_E26D,beta-lactamase_26,TEM-1,beta-lactamase,P62593,0.932647,NO,26,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.454,-2.507,0.053,,0.54,H,A,1.04,0.98,,,93.01,OAP,-1.96167,0.221079,0.00297948,0.932647 beta-lactamase_K32Y,beta-lactamase_32,TEM-1,beta-lactamase,P62593,0.932647,NO,32,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.984,-4.317,2.333,5.55842,0.563,H,A,1.82,0.34,1.754,,73.08,HBA,-2.04233,0.221079,0.00401283,0.932647 beta-lactamase_0_P250T,beta-lactamase_0_250,TEM-1,beta-lactamase_0,P62593,0.932677,NO,250,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.0500837,0.00550899,0.932677 PSD95pdz3_A375M,PSD95pdz3_375,PSD95pdz3,PSD95pdz3,P31016,0.932679,NO,375,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.307,-4.162,2.855,5.05512,,,,,13.888,,,,PHH,-1.43767,0.0758425,0.000356809,0.932679 beta-lactamase_2500_P255S,beta-lactamase_2500_255,TEM-1,beta-lactamase_2500,P62593,0.932696,NO,255,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.361275,0.00499612,0.932696 beta-lactamase_0_I285Y,beta-lactamase_0_285,TEM-1,beta-lactamase_0,P62593,0.932698,NO,285,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.0500837,0.101555,0.932698 beta-lactamase_39_M153D,beta-lactamase_39_153,TEM-1,beta-lactamase_39,P62593,0.932701,NO,153,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-3.193,-3.931,0.738,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.0495842,0.00509109,0.932701 kka2_1:2_G21L,kka2_1:2_21,Kka2,kka2_1:2,P00552,0.932704,NO,21,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.368,-3.794,2.426,,0.586,T,l,0.29,-0.75,2.026,,71.59,HOH,-2.10167,0.295029,0.00709648,0.932704 beta-lactamase_156_R257E,beta-lactamase_156_257,TEM-1,beta-lactamase_156,P62593,0.932708,NO,257,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.111618,0.00756629,0.932708 beta-lactamase_0_I261E,beta-lactamase_0_261,TEM-1,beta-lactamase_0,P62593,0.932712,NO,261,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.0500837,0.0123091,0.932712 beta-lactamase_2500_A170V,beta-lactamase_2500_170,TEM-1,beta-lactamase_2500,P62593,0.932769,NO,170,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.237,-2.64,1.403,,0.126,,L,0.46,-0.35,2.427,,64.69,AHH,-1.63267,0.361275,0.00431903,0.932769 beta-lactamase_0_K109N,beta-lactamase_0_109,TEM-1,beta-lactamase_0,P62593,0.932777,NO,109,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.734,-2.767,1.033,,0.787,G,A,2.34,2.21,15.473,15.473,72.73,ABB,-1.63333,0.0500837,0.00462493,0.932777 beta-lactamase_39_W288T,beta-lactamase_39_288,TEM-1,beta-lactamase_39,P62593,0.932804,NO,288,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,,,,,,,,,,,,,BHO,,0.0495842,,0.932804 kka2_1:1_A56E,kka2_1:1_56,Kka2,kka2_1:1,P00552,0.932811,NO,56,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.083,-2.646,0.563,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.520039,0.00717715,0.932811 PSD95pdz3_V328R,PSD95pdz3_328,PSD95pdz3,PSD95pdz3,P31016,0.932823,NO,328,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.465,-3.84,2.375,5.28275,,,,,16.8775,,,,HHO,-1.36767,0.0758425,0.000986706,0.932823 beta-lactamase_39_K190F,beta-lactamase_39_190,TEM-1,beta-lactamase_39,P62593,0.932831,NO,190,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.994,-4.396,2.402,,0.371,H,A,2.34,0.16,1.513,,77.62,BBH,-1.64167,0.0495842,0.00574527,0.932831 beta-lactamase_0_A34M,beta-lactamase_0_34,TEM-1,beta-lactamase_0,P62593,0.932846,NO,34,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.059,-4.351,2.292,,,H,A,0.46,-0.54,3.998,,73.78,AHA,-1.74967,0.0500837,0.00407913,0.932846 kka2_1:8_P98L,kka2_1:8_98,Kka2,kka2_1:8,P00552,0.932861,NO,98,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.526,-3.014,1.488,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.100394,0.00622754,0.932861 kka2_1:8_P98L,kka2_1:8_98,Kka2,kka2_1:8,P00552,0.932861,NO,98,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.526,-3.014,1.488,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.100394,0.00622754,0.932861 beta-lactamase_2500_H287M,beta-lactamase_2500_287,TEM-1,beta-lactamase_2500,P62593,0.932865,NO,287,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,,,,,,,,,,,,,BBH,-1.111,0.361275,,0.932865 beta-lactamase_625_V78C,beta-lactamase_625_78,TEM-1,beta-lactamase_625,P62593,0.93289,NO,78,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.459,-4.812,3.353,,,H,A,0.44,-0.47,2.045,,63.64,HHH,-1.17833,0.213352,0.00492501,0.93289 gb1_V247E,gb1_247,gb1,gb1,P06654,0.932895,NO,247,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.711,-3.487,1.776,,,,,,,0.805,,44.87,HHA,-1.485,0.177985,0.00435373,0.932895 gb1_Y259W,gb1_259,gb1,gb1,P06654,0.932895,NO,259,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-1.78,-2.284,0.504,,,,,,,0.131,,11.83,PHH,-1.787,0.177985,0.00464313,0.932895 beta-lactamase_156_S104Y,beta-lactamase_156_104,TEM-1,beta-lactamase_156,P62593,0.932914,NO,104,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.015,-4.223,3.208,,0.04,,b,0.27,0.57,4.02,,63.29,HPO,-1.05267,0.111618,0.00218083,0.932914 Pab1_A141N,Pab1_141,Pab1,Pab1,P04147,0.932918,NO,141,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.461,-3.502,2.041,,0.34,H,A,0.52,-0.27,2.15,,79.03,BHH,-1.19433,0.175299,0.00165974,0.932918 beta-lactamase_0_G154R,beta-lactamase_0_154,TEM-1,beta-lactamase_0,P62593,0.932921,NO,154,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.823,-3.969,3.146,,0.54,T,l,0.29,-0.56,3.629,,64.69,HOA,-1.635,0.0500837,0.00180205,0.932921 beta-lactamase_2500_R273A,beta-lactamase_2500_273,TEM-1,beta-lactamase_2500,P62593,0.932926,NO,273,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.314,-1.856,-0.458,,0.564,H,A,1.2,1.57,19.943,19.943,73.78,ABP,-1.841,0.361275,0.0077952,0.932926 beta-lactamase_39_D231H,beta-lactamase_39_231,TEM-1,beta-lactamase_39,P62593,0.932955,NO,231,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.816,-4.453,3.637,,,E,B,0.75,-1.06,0.462,,65.38,HAB,-0.994,0.0495842,0.00107395,0.932955 Pab1_V148S,Pab1_148,Pab1,Pab1,P04147,0.933014,NO,148,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.875,-2.315,0.44,,,,,,,,,,PHH,-1.43033,0.175299,0.00179641,0.933014 kka2_1:1_A79R,kka2_1:1_79,Kka2,kka2_1:1,P00552,0.933055,NO,79,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.368,-2.341,-0.027,,0.563,.,B,0.46,-0.43,7.792,7.792,71.59,HHH,-1.752,0.520039,0.00664821,0.933055 beta-lactamase_E87V,beta-lactamase_87,TEM-1,beta-lactamase,P62593,0.933068,NO,87,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.421,-2.385,0.964,5.41929,0.048,,B,0.52,0.92,1.754,,64.69,PAP,-1.969,0.221079,0.00337888,0.933068 PSD95pdz3_G345K,PSD95pdz3_345,PSD95pdz3,PSD95pdz3,P31016,0.933078,NO,345,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.008,-3.364,2.356,4.32868,,,,,13.165,,,,OOO,-1.084,0.0758425,0.000771806,0.933078 kka2_1:2_G74A,kka2_1:2_74,Kka2,kka2_1:2,P00552,0.933082,NO,74,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.18,-3.17,1.99,,0.621,T,l,0.75,0.2,1.446,,64.39,POH,-1.91667,0.295029,0.00587035,0.933082 beta-lactamase_E210D,beta-lactamase_210,TEM-1,beta-lactamase,P62593,0.933099,NO,210,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.319,-3.702,1.383,5.7398,0.476,H,A,0.52,0.75,1.555,,77.62,HAH,-1.88567,0.221079,0.00663582,0.933099 beta-lactamase_S201N,beta-lactamase_201,TEM-1,beta-lactamase,P62593,0.933099,NO,201,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.183,-3.471,2.288,4.85496,0.064,H,A,0.77,-0.07,4.045,,64.69,HPB,-1.451,0.221079,0.00198815,0.933099 beta-lactamase_0_L135P,beta-lactamase_0_135,TEM-1,beta-lactamase_0,P62593,0.933113,NO,135,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.002,-4.134,3.132,,0.117,H,A,0.55,-0.58,0.705,,43.71,PHH,-1.03767,0.0500837,0.00244423,0.933113 kka2_1:2_P179V,kka2_1:2_179,Kka2,kka2_1:2,P00552,0.933128,NO,179,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.974,-3.463,2.489,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.295029,0.00298346,0.933128 PSD95pdz3_F337S,PSD95pdz3_337,PSD95pdz3,PSD95pdz3,P31016,0.933134,NO,337,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.524,-3.292,1.768,5.22838,,,,,13.4936,,,,HHH,-1.59467,0.0758425,0.000875287,0.933134 gb1_N234T,gb1_234,gb1,gb1,P06654,0.933139,NO,234,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-2.055,-3.192,1.137,,,,,,,1.235,,45.54,HPO,-2.05067,0.177985,0.00242189,0.933139 kka2_1:8_R253V,kka2_1:8_253,Kka2,kka2_1:8,P00552,0.933183,NO,253,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.356,-3.689,2.333,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.100394,0.0144195,0.933183 kka2_1:8_R253V,kka2_1:8_253,Kka2,kka2_1:8,P00552,0.933183,NO,253,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.356,-3.689,2.333,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.100394,0.0144195,0.933183 kka2_1:2_A191L,kka2_1:2_191,Kka2,kka2_1:2,P00552,0.933206,NO,191,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.831,-3.249,2.418,,,.,b,0.46,-0.94,2.046,,50,AHO,-0.868667,0.295029,0.00338807,0.933206 beta-lactamase_0_A182W,beta-lactamase_0_182,TEM-1,beta-lactamase_0,P62593,0.93323,NO,182,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.777,-5.53,3.753,,0.136,H,A,0.46,-0.66,10.765,10.765,93.01,OHH,-1.27367,0.0500837,0.00559099,0.93323 beta-lactamase_0_R81E,beta-lactamase_0_81,TEM-1,beta-lactamase_0,P62593,0.933256,NO,81,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.466,-2.677,1.211,,0.218,H,A,1.2,1.66,0.332,,50,PBH,-1.60667,0.0500837,0.00499763,0.933256 kka2_1:4_E169M,kka2_1:4_169,Kka2,kka2_1:4,P00552,0.933267,NO,169,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.996,-3.601,1.605,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.168804,0.00730086,0.933267 beta-lactamase_0_I45K,beta-lactamase_0_45,TEM-1,beta-lactamase_0,P62593,0.933295,NO,45,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-2.421,-3.76,1.339,,,E,B,0.48,-0.3,1.375,,77.62,HHA,-2.30267,0.0500837,0.00452842,0.933295 beta-lactamase_W163G,beta-lactamase_163,TEM-1,beta-lactamase,P62593,0.933331,NO,163,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-1.843,-2.648,0.805,6.2765,0.467,,B,1.22,-0.5,3.642,,63.99,BHA,-1.269,0.221079,0.00418955,0.933331 Pab1_A158N,Pab1_158,Pab1,Pab1,P04147,0.933334,NO,158,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.154,-3.819,2.665,,,,,,,1.197,,56.33,HHP,-1.40733,0.175299,0.000649733,0.933334 kka2_1:4_T187A,kka2_1:4_187,Kka2,kka2_1:4,P00552,0.933351,NO,187,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.273,-1.915,0.642,,0.007,E,B,0.22,-0.85,2.73,,52.27,HPB,-1.06567,0.168804,0.00693073,0.933351 beta-lactamase_0_A215G,beta-lactamase_0_215,TEM-1,beta-lactamase_0,P62593,0.933364,NO,215,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.503,-1.579,0.076,,,,a,0.46,-0.93,0.494,,74.48,HHO,-1.42633,0.0500837,0.00544007,0.933364 kka2_1:4_A87S,kka2_1:4_87,Kka2,kka2_1:4,P00552,0.93337,NO,87,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.917,-2.911,0.994,,1.039,S,L,0.46,1.57,22.675,22.675,65.53,AHO,-1.822,0.168804,0.00791281,0.93337 beta-lactamase_2500_G265D,beta-lactamase_2500_265,TEM-1,beta-lactamase_2500,P62593,0.933375,NO,265,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.361275,0.00811926,0.933375 beta-lactamase_0_R275K,beta-lactamase_0_275,TEM-1,beta-lactamase_0,P62593,0.933392,NO,275,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.0500837,0.0141984,0.933392 beta-lactamase_Q265N,beta-lactamase_265,TEM-1,beta-lactamase,P62593,0.933395,NO,265,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.58,-3.039,0.459,6.62674,1.116,,A,0.03,1.17,12.514,12.514,69.58,PPH,-1.978,0.221079,0.00811926,0.933395 beta-lactamase_2500_R41N,beta-lactamase_2500_41,TEM-1,beta-lactamase_2500,P62593,0.933397,NO,41,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-0.942,-3.445,2.503,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.361275,0.00123327,0.933397 beta-lactamase_156_S80K,beta-lactamase_156_80,TEM-1,beta-lactamase_156,P62593,0.93346,NO,80,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.029,-2.901,0.872,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.111618,0.00565569,0.93346 beta-lactamase_2500_E169F,beta-lactamase_2500_169,TEM-1,beta-lactamase_2500,P62593,0.93346,NO,169,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.23,-4.322,3.092,,0.337,,A,1.04,1,1.806,,73.08,PAH,-1.16533,0.361275,0.00400994,0.93346 beta-lactamase_A215S,beta-lactamase_215,TEM-1,beta-lactamase,P62593,0.933461,NO,215,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.503,-2.232,0.729,4.82164,,,a,0.75,-0.93,3.583,,74.48,HHO,-1.42633,0.221079,0.00544007,0.933461 beta-lactamase_P172W,beta-lactamase_172,TEM-1,beta-lactamase,P62593,0.933461,NO,172,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.998,-5.528,4.53,5.98941,0.639,T,b,1.1,0.24,2.087,,74.48,HOP,-2.03067,0.221079,0.00312594,0.933461 beta-lactamase_2500_H24M,beta-lactamase_2500_24,TEM-1,beta-lactamase_2500,P62593,0.933475,NO,24,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-2.481,-3.144,0.663,,,,,,,0.467,,93.01,OBO,-2.0035,0.361275,0.00238894,0.933475 beta-lactamase_2500_T112C,beta-lactamase_2500_112,TEM-1,beta-lactamase_2500,P62593,0.93349,NO,112,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.186,-5.027,2.841,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.361275,0.00531334,0.93349 beta-lactamase_2500_H110G,beta-lactamase_2500_110,TEM-1,beta-lactamase_2500,P62593,0.933495,NO,110,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-1.706,-3.573,1.867,,0.341,G,a,0.17,1.08,31.31,31.31,64.69,BBH,-1.73333,0.361275,0.00441499,0.933495 beta-lactamase_2500_M180I,beta-lactamase_2500_180,TEM-1,beta-lactamase_2500,P62593,0.933551,NO,180,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-2.795,-3.664,0.869,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.361275,0.00552048,0.933551 kka2_1:2_E169A,kka2_1:2_169,Kka2,kka2_1:2,P00552,0.933585,NO,169,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.996,-2.303,0.307,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.295029,0.00730086,0.933585 beta-lactamase_0_L137P,beta-lactamase_0_137,TEM-1,beta-lactamase_0,P62593,0.933591,NO,137,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.03,-4.134,3.104,,,H,A,0.55,-0.38,0.328,,42.31,HHP,-1.58933,0.0500837,0.00278599,0.933591 beta-lactamase_39_E62H,beta-lactamase_39_62,TEM-1,beta-lactamase_39,P62593,0.933597,NO,62,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.193,-4.429,3.236,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.0495842,0.00264802,0.933597 beta-lactamase_156_R162F,beta-lactamase_156_162,TEM-1,beta-lactamase_156,P62593,0.933607,NO,162,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.016,-4.266,3.25,,0.124,S,B,1.2,-0.37,7.444,,64.69,ABH,-1.25,0.111618,0.000561334,0.933607 beta-lactamase_0_P250S,beta-lactamase_0_250,TEM-1,beta-lactamase_0,P62593,0.93362,NO,250,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.0500837,0.00550899,0.93362 beta-lactamase_0_A225S,beta-lactamase_0_225,TEM-1,beta-lactamase_0,P62593,0.933626,NO,225,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.845,-2.863,1.018,,1,T,B,0.46,-0.38,11.722,11.722,74.48,OHO,-1.39967,0.0500837,0.00465057,0.933626 beta-lactamase_625_A246T,beta-lactamase_625_246,TEM-1,beta-lactamase_625,P62593,0.933639,NO,246,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.121,-3.507,1.386,,0.01,E,B,0.46,-1.01,1.201,,73.78,HHH,-1.55633,0.213352,0.00569458,0.933639 beta-lactamase_2500_E46K,beta-lactamase_2500_46,TEM-1,beta-lactamase_2500,P62593,0.933655,NO,46,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.94,-3.66,1.72,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.361275,0.00427568,0.933655 beta-lactamase_V157V,beta-lactamase_157,TEM-1,beta-lactamase,P62593,0.933663,NO,157,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.751,-1.751,,5.51733,0.308,S,a,0.96,-0.75,1.847,,69.58,BHP,-2.00767,0.221079,0.00506849,0.933663 beta-lactamase_39_I277H,beta-lactamase_39_277,TEM-1,beta-lactamase_39,P62593,0.93368,NO,277,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.0495842,0.0169305,0.93368 beta-lactamase_2500_T147Q,beta-lactamase_2500_147,TEM-1,beta-lactamase_2500,P62593,0.933713,NO,147,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.149,-3.979,2.83,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.361275,0.00226017,0.933713 kka2_1:8_R140F,kka2_1:8_140,Kka2,kka2_1:8,P00552,0.933716,NO,140,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.351,-4.407,3.056,,0.12,H,A,0.16,0.2,2.874,,53.03,BBH,-1.885,0.100394,0.00430167,0.933716 kka2_1:8_R140F,kka2_1:8_140,Kka2,kka2_1:8,P00552,0.933716,NO,140,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.351,-4.407,3.056,,0.12,H,A,0.16,0.2,2.874,,53.03,BBH,-1.885,0.100394,0.00430167,0.933716 beta-lactamase_625_A247Q,beta-lactamase_625_247,TEM-1,beta-lactamase_625,P62593,0.93374,NO,247,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.213352,0.00611275,0.93374 kka2_1:2_T51C,kka2_1:2_51,Kka2,kka2_1:2,P00552,0.933745,NO,51,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.199,-3.244,1.045,,0.05,E,B,0.22,-0.05,13.165,13.165,63.64,BPA,-1.76767,0.295029,0.00628861,0.933745 beta-lactamase_L197M,beta-lactamase_197,TEM-1,beta-lactamase,P62593,0.933757,NO,197,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.853,-3.888,3.035,5.19172,0.007,S,B,1.3,0.33,1.756,,60.14,HHP,-1.833,0.221079,0.00144602,0.933757 PSD95pdz3_S339T,PSD95pdz3_339,PSD95pdz3,PSD95pdz3,P31016,0.933801,NO,339,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.519,-2.653,1.134,5.34493,,,,,12.2167,,,,HPH,-1.55767,0.0758425,0.00084982,0.933801 gb1_T281Y,gb1_281,gb1,gb1,P06654,0.933869,NO,281,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.828,-4.051,2.223,,,,,,,1.038,,35.71,HPA,-1.63667,0.177985,0.00284418,0.933869 gb1_Y259L,gb1_259,gb1,gb1,P06654,0.933869,NO,259,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-1.78,-2.955,1.175,,,,,,,0.131,,11.83,PHH,-1.787,0.177985,0.00464313,0.933869 beta-lactamase_39_D161M,beta-lactamase_39_161,TEM-1,beta-lactamase_39,P62593,0.933905,NO,161,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.891,-4.899,4.008,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.0495842,0.000897697,0.933905 beta-lactamase_156_R91C,beta-lactamase_156_91,TEM-1,beta-lactamase_156,P62593,0.93391,NO,91,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.392,-5.127,3.735,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.111618,0.00380226,0.93391 Pab1_I183F,Pab1_183,Pab1,Pab1,P04147,0.933915,NO,183,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.302,-3.538,2.236,,0.308,T,B,1,1.08,1.29,,75.56,HHA,-1.27167,0.175299,0.000574345,0.933915 beta-lactamase_0_Q276S,beta-lactamase_0_276,TEM-1,beta-lactamase_0,P62593,0.933921,NO,276,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.0500837,0.0191712,0.933921 kka2_1:1_Q155M,kka2_1:1_155,Kka2,kka2_1:1,P00552,0.93394,NO,155,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.606,-4.733,2.127,,0.525,T,A,0.4,1.49,4.415,,63.64,APA,-1.726,0.520039,0.00641853,0.93394 beta-lactamase_L219F,beta-lactamase_219,TEM-1,beta-lactamase,P62593,0.933946,NO,219,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.313,-2.825,1.512,5.74153,,I,A,0.84,-0.51,2.321,,74.48,HHB,-1.21533,0.221079,0.00664345,0.933946 beta-lactamase_S221D,beta-lactamase_221,TEM-1,beta-lactamase,P62593,0.933946,NO,221,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.754,-3.645,1.891,5.77407,0.624,H,A,0.74,-0.2,0.383,,74.48,BPH,-1.59967,0.221079,0.0046094,0.933946 beta-lactamase_39_Q203K,beta-lactamase_39_203,TEM-1,beta-lactamase_39,P62593,0.933952,NO,203,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.168,-2.642,0.474,,0.47,H,A,0.64,-0.38,1.453,,65.38,BPP,-1.614,0.0495842,0.00631514,0.933952 PSD95pdz3_G356E,PSD95pdz3_356,PSD95pdz3,PSD95pdz3,P31016,0.933963,NO,356,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.008,-3.347,2.339,4.8656,,,,,11.9575,,,,BOA,-1.22933,0.0758425,0.000623061,0.933963 beta-lactamase_156_E272F,beta-lactamase_156_272,TEM-1,beta-lactamase_156,P62593,0.933974,NO,272,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.111618,0.00545371,0.933974 beta-lactamase_0_V82I,beta-lactamase_0_82,TEM-1,beta-lactamase_0,P62593,0.933977,NO,82,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.325,-2.197,0.872,,0.267,H,A,0.44,0.08,1.893,,93.01,BHA,-1.28567,0.0500837,0.00397046,0.933977 beta-lactamase_T107C,beta-lactamase_107,TEM-1,beta-lactamase,P62593,0.934004,NO,107,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.117,-4.664,3.547,5.23432,,G,A,2.12,-0.06,3.676,,67.83,HPA,-1.265,0.221079,0.00239347,0.934004 Pab1_K140P,Pab1_140,Pab1,Pab1,P04147,0.934007,NO,140,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.083,-3.472,2.389,,0.345,H,A,,-0.73,,,,PBH,-1.20767,0.175299,0.000337366,0.934007 kka2_1:8_L123V,kka2_1:8_123,Kka2,kka2_1:8,P00552,0.934048,NO,123,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.888,-2.888,2,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.100394,0.00325188,0.934048 kka2_1:8_L123V,kka2_1:8_123,Kka2,kka2_1:8,P00552,0.934048,NO,123,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.888,-2.888,2,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.100394,0.00325188,0.934048 kka2_1:8_W24C,kka2_1:8_24,Kka2,kka2_1:8,P00552,0.934048,NO,24,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-1.779,-3.129,1.35,,0.477,E,B,1.51,-0.21,2.503,,56.06,AHH,-2.24467,0.100394,0.00631564,0.934048 kka2_1:8_W24C,kka2_1:8_24,Kka2,kka2_1:8,P00552,0.934048,NO,24,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-1.779,-3.129,1.35,,0.477,E,B,1.51,-0.21,2.503,,56.06,AHH,-2.24467,0.100394,0.00631564,0.934048 beta-lactamase_2500_L28Q,beta-lactamase_2500_28,TEM-1,beta-lactamase_2500,P62593,0.934058,NO,28,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.579,-2.97,1.391,,0.277,H,A,0.55,-0.16,2.716,,93.01,PHH,-2.11333,0.361275,0.00359321,0.934058 kka2_1:8_L184F,kka2_1:8_184,Kka2,kka2_1:8,P00552,0.934068,NO,184,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.496,-2.947,1.451,,0.489,E,B,0.55,-0.06,4.495,,63.26,AHH,-1.24833,0.100394,0.00518742,0.934068 kka2_1:8_L184F,kka2_1:8_184,Kka2,kka2_1:8,P00552,0.934068,NO,184,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.496,-2.947,1.451,,0.489,E,B,0.55,-0.06,4.495,,63.26,AHH,-1.24833,0.100394,0.00518742,0.934068 kka2_1:8_E231W,kka2_1:8_231,Kka2,kka2_1:8,P00552,0.934092,NO,231,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.002,-5.602,3.6,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.100394,0.00732383,0.934092 kka2_1:8_E231W,kka2_1:8_231,Kka2,kka2_1:8,P00552,0.934092,NO,231,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.002,-5.602,3.6,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.100394,0.00732383,0.934092 gb1_Q258T,gb1_258,gb1,gb1,P06654,0.934111,NO,258,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.095,-3.212,1.117,,,,,,,0.86,,37.28,BPH,-1.88333,0.177985,0.00437595,0.934111 beta-lactamase_T179S,beta-lactamase_179,TEM-1,beta-lactamase,P62593,0.934113,NO,179,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.085,-2.228,1.143,5.07116,,E,B,0.8,-1.38,1.859,,73.08,PPH,-1.557,0.221079,0.00226045,0.934113 beta-lactamase_P249Q,beta-lactamase_249,TEM-1,beta-lactamase,P62593,0.934147,NO,249,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.312,-4.016,2.704,5.10655,0.256,S,B,0.99,0.04,0.479,,72.73,OOA,-1.81367,0.221079,0.00220169,0.934147 beta-lactamase_0_V260C,beta-lactamase_0_260,TEM-1,beta-lactamase_0,P62593,0.934177,NO,260,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.0500837,0.00471757,0.934177 kka2_1:4_R173Y,kka2_1:4_173,Kka2,kka2_1:4,P00552,0.934189,NO,173,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.407,-3.028,0.621,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.168804,0.00784999,0.934189 beta-lactamase_0_D271S,beta-lactamase_0_271,TEM-1,beta-lactamase_0,P62593,0.9342,NO,271,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.0500837,0.00752082,0.9342 beta-lactamase_156_T178M,beta-lactamase_156_178,TEM-1,beta-lactamase_156,P62593,0.93421,NO,178,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-0.791,-4.48,3.689,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.111618,0.000684366,0.93421 beta-lactamase_0_S104M,beta-lactamase_0_104,TEM-1,beta-lactamase_0,P62593,0.934219,NO,104,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.015,-4.54,3.525,,0.04,,b,0.27,0.57,1.148,,63.29,HPO,-1.05267,0.0500837,0.00218083,0.934219 beta-lactamase_39_K213T,beta-lactamase_39_213,TEM-1,beta-lactamase_39,P62593,0.934227,NO,213,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.81,-2.431,0.621,,0.67,,A,2.34,0.29,2.648,,67.83,ABH,-1.57767,0.0495842,0.00610411,0.934227 beta-lactamase_2500_E169Y,beta-lactamase_2500_169,TEM-1,beta-lactamase_2500,P62593,0.934228,NO,169,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.23,-4.247,3.017,,0.337,,A,1.04,1,1.806,,73.08,PAH,-1.16533,0.361275,0.00400994,0.934228 beta-lactamase_39_D271Y,beta-lactamase_39_271,TEM-1,beta-lactamase_39,P62593,0.934259,NO,271,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.0495842,0.00752082,0.934259 beta-lactamase_A170H,beta-lactamase_170,TEM-1,beta-lactamase,P62593,0.93426,NO,170,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.237,-4.694,3.457,5.19261,0.126,,L,2.34,-0.35,2.427,,64.69,AHH,-1.63267,0.221079,0.00431903,0.93426 beta-lactamase_625_G76I,beta-lactamase_625_76,TEM-1,beta-lactamase_625,P62593,0.934266,NO,76,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.189,-3.948,2.759,,,H,A,0.29,-0.67,3.059,,67.83,OOH,-1.22267,0.213352,0.00476637,0.934266 beta-lactamase_2500_T198D,beta-lactamase_2500_198,TEM-1,beta-lactamase_2500,P62593,0.934267,NO,198,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.168,-3.544,1.376,,0.489,,B,0.22,-0.13,0.37,,73.78,HPH,-1.98767,0.361275,0.004311,0.934267 beta-lactamase_156_M67C,beta-lactamase_156_67,TEM-1,beta-lactamase_156,P62593,0.934275,NO,67,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-2.231,-2.364,0.133,,0.006,G,P,0.55,-0.81,1.463,,65.03,HHP,-1.502,0.111618,0.00409753,0.934275 beta-lactamase_39_D33N,beta-lactamase_39_33,TEM-1,beta-lactamase_39,P62593,0.934302,NO,33,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.321,-2.983,0.662,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.0495842,0.00435556,0.934302 beta-lactamase_2500_E56R,beta-lactamase_2500_56,TEM-1,beta-lactamase_2500,P62593,0.934303,NO,56,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.043,-3.679,1.636,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.361275,0.00238534,0.934303 kka2_1:2_D33A,kka2_1:2_33,Kka2,kka2_1:2,P00552,0.934315,NO,33,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.186,-2.11,-0.076,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.295029,0.00633568,0.934315 WW_domain_P172E,WW_domain_172,Yap65,WW_domain,P46937,0.934325,NO,172,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.035,-3.217,2.182,,,,,,,,,,HOH,-1.233,0.153962,0.000991485,0.934325 kka2_1:4_Q100Y,kka2_1:4_100,Kka2,kka2_1:4,P00552,0.93433,NO,100,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.77,-4.334,1.564,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.168804,0.0066405,0.93433 beta-lactamase_R238V,beta-lactamase_238,TEM-1,beta-lactamase,P62593,0.934354,NO,238,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.002,-3.732,1.73,5.87663,0.564,T,L,0.45,1.09,4.195,,72.73,ABO,-1.62633,0.221079,0.00743256,0.934354 kka2_1:8_V36I,kka2_1:8_36,Kka2,kka2_1:8,P00552,0.934369,NO,36,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-0.898,-1.989,1.091,,0.292,E,B,1.48,0.21,0.938,,52.27,HHH,-1.484,0.100394,0.00245633,0.934369 kka2_1:8_V36I,kka2_1:8_36,Kka2,kka2_1:8,P00552,0.934369,NO,36,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-0.898,-1.989,1.091,,0.292,E,B,1.48,0.21,0.938,,52.27,HHH,-1.484,0.100394,0.00245633,0.934369 beta-lactamase_F22K,beta-lactamase_22,TEM-1,beta-lactamase,P62593,0.934392,NO,22,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-2.676,-3.736,1.06,,,,,,,1.616,,73.08,HHH,-2.03233,0.221079,0.00262842,0.934392 beta-lactamase_P165V,beta-lactamase_165,TEM-1,beta-lactamase,P62593,0.934392,NO,165,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.373,-3.333,1.96,5.33889,0.203,T,A,0.99,-0.31,0.414,,73.78,AOA,-1.359,0.221079,0.00549538,0.934392 beta-lactamase_39_E62D,beta-lactamase_39_62,TEM-1,beta-lactamase_39,P62593,0.934404,NO,62,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.193,-2.088,0.895,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.0495842,0.00264802,0.934404 beta-lactamase_0_P250C,beta-lactamase_0_250,TEM-1,beta-lactamase_0,P62593,0.934457,NO,250,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.0500837,0.00550899,0.934457 beta-lactamase_E102G,beta-lactamase_102,TEM-1,beta-lactamase,P62593,0.934488,NO,102,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.118,-2.728,0.61,6.36157,0.722,S,B,1.5,1.82,1.336,,73.08,HAH,-1.581,0.221079,0.00486633,0.934488 beta-lactamase_K213E,beta-lactamase_213,TEM-1,beta-lactamase,P62593,0.934526,NO,213,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.81,-2.688,0.878,5.63167,0.67,,A,1.59,0.29,3.924,,67.83,ABH,-1.57767,0.221079,0.00610411,0.934526 beta-lactamase_S2R,beta-lactamase_2,TEM-1,beta-lactamase,P62593,0.934532,NO,2,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.942,-3.827,1.885,,,,,,,2.36,,65.38,HPH,-2.02767,0.221079,0.00227352,0.934532 kka2_1:8_T125F,kka2_1:8_125,Kka2,kka2_1:8,P00552,0.93455,NO,125,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.622,-4.443,1.821,,0.791,T,A,0.22,0.33,2.675,,92.05,BPH,-1.56933,0.100394,0.00821755,0.93455 kka2_1:8_T125F,kka2_1:8_125,Kka2,kka2_1:8,P00552,0.93455,NO,125,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.622,-4.443,1.821,,0.791,T,A,0.22,0.33,2.675,,92.05,BPH,-1.56933,0.100394,0.00821755,0.93455 PSD95pdz3_Q384D,PSD95pdz3_384,PSD95pdz3,PSD95pdz3,P31016,0.934574,NO,384,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-1.699,-2.925,1.226,5.49339,,,,,23.54,,,,OPP,-1.41333,0.0758425,0.000216736,0.934574 beta-lactamase_2500_P217H,beta-lactamase_2500_217,TEM-1,beta-lactamase_2500,P62593,0.934585,NO,217,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-2.062,-3.354,1.292,,0.496,I,A,0.52,-0.33,0.431,,74.48,OOH,-1.64333,0.361275,0.00463211,0.934585 beta-lactamase_0_K71S,beta-lactamase_0_71,TEM-1,beta-lactamase_0,P62593,0.934644,NO,71,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-0.8,-3.161,2.361,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.0500837,0.00103192,0.934644 kka2_1:1_G234L,kka2_1:1_234,Kka2,kka2_1:1,P00552,0.934667,NO,234,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-2.9,-3.687,0.787,,0.494,H,A,0.29,-0.29,1.753,,71.59,OOA,-1.86767,0.520039,0.00984449,0.934667 kka2_1:8_Q100H,kka2_1:8_100,Kka2,kka2_1:8,P00552,0.93467,NO,100,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.77,-2.906,0.136,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.100394,0.0066405,0.93467 kka2_1:8_Q100H,kka2_1:8_100,Kka2,kka2_1:8,P00552,0.93467,NO,100,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.77,-2.906,0.136,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.100394,0.0066405,0.93467 beta-lactamase_2500_P255I,beta-lactamase_2500_255,TEM-1,beta-lactamase_2500,P62593,0.934671,NO,255,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.361275,0.00499612,0.934671 beta-lactamase_0_L38D,beta-lactamase_0_38,TEM-1,beta-lactamase_0,P62593,0.934676,NO,38,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.343,-3.97,2.627,,0.088,H,A,0.55,0.2,13.556,13.556,64.34,PHO,-1.78033,0.0500837,0.00373244,0.934676 Pab1_D151L,Pab1_151,Pab1,Pab1,P04147,0.934733,NO,151,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.399,-3.464,1.065,,,,,,,,,,OAH,-1.51767,0.175299,0.00228155,0.934733 kka2_1:1_H8C,kka2_1:1_8,Kka2,kka2_1:1,P00552,0.934785,NO,8,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-2.759,-2.768,0.009,,,,,,,16.971,16.971,71.59,HBH,-2.25467,0.520039,0.00256422,0.934785 beta-lactamase_39_D113R,beta-lactamase_39_113,TEM-1,beta-lactamase_39,P62593,0.934818,NO,113,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.829,-2.854,1.025,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.0495842,0.00474112,0.934818 beta-lactamase_2500_I277M,beta-lactamase_2500_277,TEM-1,beta-lactamase_2500,P62593,0.934836,NO,277,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.361275,0.0169305,0.934836 beta-lactamase_625_A123T,beta-lactamase_625_123,TEM-1,beta-lactamase_625,P62593,0.934843,NO,123,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.834,-3.222,2.388,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.213352,0.0010157,0.934843 beta-lactamase_156_T69L,beta-lactamase_156_69,TEM-1,beta-lactamase_156,P62593,0.934844,NO,69,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-0.973,-3.213,2.24,,,G,A,0.22,-1.24,4.194,,93.01,PPH,-1.01833,0.111618,0.00127498,0.934844 kka2_1:1_L81V,kka2_1:1_81,Kka2,kka2_1:1,P00552,0.934866,NO,81,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.427,-1.839,0.412,,0.46,E,A,0.55,-0.14,0.374,,63.64,HHA,-1.50567,0.520039,0.00805839,0.934866 beta-lactamase_39_E62F,beta-lactamase_39_62,TEM-1,beta-lactamase_39,P62593,0.934872,NO,62,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.193,-4.376,3.183,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.0495842,0.00264802,0.934872 beta-lactamase_2500_E26R,beta-lactamase_2500_26,TEM-1,beta-lactamase_2500,P62593,0.934889,NO,26,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.454,-2.433,-0.021,,0.54,H,A,1.04,0.98,0.49,,93.01,OAP,-1.96167,0.361275,0.00297948,0.934889 kka2_1:8_A137D,kka2_1:8_137,Kka2,kka2_1:8,P00552,0.934911,NO,137,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.156,-4.088,1.932,,0.029,H,A,1.04,0.34,2.886,,63.26,PHB,-2.559,0.100394,0.00515054,0.934911 kka2_1:8_A137D,kka2_1:8_137,Kka2,kka2_1:8,P00552,0.934911,NO,137,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.156,-4.088,1.932,,0.029,H,A,1.04,0.34,2.886,,63.26,PHB,-2.559,0.100394,0.00515054,0.934911 beta-lactamase_2500_M127R,beta-lactamase_2500_127,TEM-1,beta-lactamase_2500,P62593,0.934918,NO,127,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-2.251,-2.722,0.471,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.361275,0.00437927,0.934918 beta-lactamase_V257L,beta-lactamase_257,TEM-1,beta-lactamase,P62593,0.934958,NO,257,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.533,-2.096,0.563,5.31999,,E,B,0.96,-0.7,1.463,,58.74,HHH,-1.70967,0.221079,0.00756629,0.934958 beta-lactamase_625_A235V,beta-lactamase_625_235,TEM-1,beta-lactamase_625,P62593,0.934965,NO,235,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.266,-2.665,1.399,,0.32,E,B,0.46,-0.86,0.281,,50,OHO,-0.89,0.213352,0.00493474,0.934965 beta-lactamase_2500_L160S,beta-lactamase_2500_160,TEM-1,beta-lactamase_2500,P62593,0.934979,NO,160,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.977,-3.653,2.676,,0.022,,B,0.55,-0.6,0.895,,44.41,BHA,-0.936,0.361275,0.00193775,0.934979 kka2_1:2_L53P,kka2_1:2_53,Kka2,kka2_1:2,P00552,0.935009,NO,53,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-2.681,-2.005,-0.676,,0.569,E,B,0.55,0.8,19.536,19.536,71.59,AHP,-2.47433,0.295029,0.00671168,0.935009 beta-lactamase_0_L160V,beta-lactamase_0_160,TEM-1,beta-lactamase_0,P62593,0.935017,NO,160,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.977,-2.271,1.294,,0.022,,B,0.55,-0.6,0.68,,44.41,BHA,-0.936,0.0500837,0.00193775,0.935017 beta-lactamase_0_M66A,beta-lactamase_0_66,TEM-1,beta-lactamase_0,P62593,0.935021,NO,66,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.362,-3.154,1.792,,0.013,,A,0.55,-0.7,1.204,,73.08,OHH,-1.49567,0.0500837,0.00412876,0.935021 Pab1_N187I,Pab1_187,Pab1,Pab1,P04147,0.93503,NO,187,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-1.224,-3.881,2.657,,0.456,S,b,,1.87,,,,HPO,-1.272,0.175299,0.00083165,0.93503 beta-lactamase_39_M180K,beta-lactamase_39_180,TEM-1,beta-lactamase_39,P62593,0.935062,NO,180,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-2.795,-3.525,0.73,,0.242,,B,0.55,-0.94,3.579,,77.62,PHO,-1.56433,0.0495842,0.00552048,0.935062 kka2_1:8_R140T,kka2_1:8_140,Kka2,kka2_1:8,P00552,0.935071,NO,140,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.351,-2.806,1.455,,0.12,H,A,0.16,0.2,2.874,,53.03,BBH,-1.885,0.100394,0.00430167,0.935071 kka2_1:8_R140T,kka2_1:8_140,Kka2,kka2_1:8,P00552,0.935071,NO,140,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.351,-2.806,1.455,,0.12,H,A,0.16,0.2,2.874,,53.03,BBH,-1.885,0.100394,0.00430167,0.935071 kka2_1:8_V214R,kka2_1:8_214,Kka2,kka2_1:8,P00552,0.935071,NO,214,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.261,-3.109,1.848,,0.117,E,B,1.48,-0.31,1.859,,64.39,OHH,-0.941667,0.100394,0.00692782,0.935071 kka2_1:8_V214R,kka2_1:8_214,Kka2,kka2_1:8,P00552,0.935071,NO,214,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.261,-3.109,1.848,,0.117,E,B,1.48,-0.31,1.859,,64.39,OHH,-0.941667,0.100394,0.00692782,0.935071 kka2_1:1_V46C,kka2_1:1_46,Kka2,kka2_1:1,P00552,0.935085,NO,46,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-2.62,-3.346,0.726,,0.192,.,B,0.44,-1.12,20.149,20.149,92.05,OHH,-1.88633,0.520039,0.00631301,0.935085 beta-lactamase_2500_R273T,beta-lactamase_2500_273,TEM-1,beta-lactamase_2500,P62593,0.935128,NO,273,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.314,-3.558,1.244,,0.564,H,A,1.2,1.57,19.943,19.943,73.78,ABP,-1.841,0.361275,0.0077952,0.935128 beta-lactamase_M180L,beta-lactamase_180,TEM-1,beta-lactamase,P62593,0.935144,NO,180,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-2.795,-3.19,0.395,4.96809,0.242,,B,1.07,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.221079,0.00552048,0.935144 beta-lactamase_0_I229C,beta-lactamase_0_229,TEM-1,beta-lactamase_0,P62593,0.935171,NO,229,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.267,-4.722,3.455,,0.083,E,B,0.48,-0.76,1.69,,50,HHH,-1.58767,0.0500837,0.00477249,0.935171 kka2_1:1_H8G,kka2_1:1_8,Kka2,kka2_1:1,P00552,0.935178,NO,8,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-2.759,-2.248,-0.511,,,,,,,16.971,16.971,71.59,HBH,-2.25467,0.520039,0.00256422,0.935178 Pab1_I137V,Pab1_137,Pab1,Pab1,P04147,0.935179,NO,137,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.212,-2.221,1.009,,0.068,,B,0.77,0.35,,,,AHA,-1.314,0.175299,0.000342224,0.935179 beta-lactamase_39_V117R,beta-lactamase_39_117,TEM-1,beta-lactamase_39,P62593,0.935188,NO,117,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.53,-4.17,2.64,,,H,A,0.44,-0.34,1.182,,65.03,PHB,-1.741,0.0495842,0.00467906,0.935188 beta-lactamase_156_V101H,beta-lactamase_156_101,TEM-1,beta-lactamase_156,P62593,0.935194,NO,101,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.295,-4.92,3.625,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.111618,0.00374492,0.935194 beta-lactamase_G216S,beta-lactamase_216,TEM-1,beta-lactamase,P62593,0.935204,NO,216,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.477,-3.283,1.806,4.91694,0.437,I,A,0.23,-0.58,1.718,,74.48,HOO,-1.68067,0.221079,0.00639568,0.935204 beta-lactamase_39_A170D,beta-lactamase_39_170,TEM-1,beta-lactamase_39,P62593,0.935213,NO,170,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.237,-3.712,2.475,,0.126,,L,0.46,-0.35,3.7,,64.69,AHH,-1.63267,0.0495842,0.00431903,0.935213 kka2_1:1_D101Q,kka2_1:1_101,Kka2,kka2_1:1,P00552,0.935232,NO,101,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.028,-3.859,2.831,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.520039,0.00423361,0.935232 PSD95pdz3_K380S,PSD95pdz3_380,PSD95pdz3,PSD95pdz3,P31016,0.935247,NO,380,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.416,-2.842,1.426,5.87979,,,,,19.6722,,,,HBP,-1.391,0.0758425,0.000281399,0.935247 beta-lactamase_0_E169Y,beta-lactamase_0_169,TEM-1,beta-lactamase_0,P62593,0.935278,NO,169,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.23,-4.247,3.017,,0.337,,A,1.04,1,3.516,,73.08,PAH,-1.16533,0.0500837,0.00400994,0.935278 beta-lactamase_T147Q,beta-lactamase_147,TEM-1,beta-lactamase,P62593,0.935302,NO,147,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.149,-3.979,2.83,5.37474,0.281,H,A,0.8,-0.68,2.838,,64.34,HPH,-1.456,0.221079,0.00226017,0.935302 beta-lactamase_2500_L28Y,beta-lactamase_2500_28,TEM-1,beta-lactamase_2500,P62593,0.935304,NO,28,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.579,-4.094,2.515,,0.277,H,A,0.55,-0.16,2.716,,93.01,PHH,-2.11333,0.361275,0.00359321,0.935304 gb1_T281V,gb1_281,gb1,gb1,P06654,0.935318,NO,281,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.828,-3.177,1.349,,,,,,,1.038,,35.71,HPA,-1.63667,0.177985,0.00284418,0.935318 beta-lactamase_39_K213R,beta-lactamase_39_213,TEM-1,beta-lactamase_39,P62593,0.93532,NO,213,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.81,-1.968,0.158,,0.67,,A,2.34,0.29,2.648,,67.83,ABH,-1.57767,0.0495842,0.00610411,0.93532 Pab1_E181I,Pab1_181,Pab1,Pab1,P04147,0.935378,NO,181,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.767,-3.743,1.976,,,,,,,1.395,,73.83,BAH,-1.575,0.175299,0.00107557,0.935378 beta-lactamase_0_T27N,beta-lactamase_0_27,TEM-1,beta-lactamase_0,P62593,0.935385,NO,27,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.905,-2.525,0.62,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.0500837,0.00306559,0.935385 kka2_1:2_E231I,kka2_1:2_231,Kka2,kka2_1:2,P00552,0.935391,NO,231,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.002,-3.963,1.961,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.295029,0.00732383,0.935391 beta-lactamase_2500_H94D,beta-lactamase_2500_94,TEM-1,beta-lactamase_2500,P62593,0.935425,NO,94,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-2.5,-3,0.5,,0.776,,B,0.17,1.24,1.176,,77.62,HBH,-1.872,0.361275,0.00389226,0.935425 beta-lactamase_625_P65S,beta-lactamase_625_65,TEM-1,beta-lactamase_625,P62593,0.935437,NO,65,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.894,-3.44,2.546,,0.098,E,B,0.52,-0.62,0.3,,40.56,HOH,-1.03233,0.213352,0.00152776,0.935437 E1_Ubiquitin_Q40Y,E1_Ubiquitin_40,Uba1,E1_Ubiquitin,P0CG63,0.935455,NO,40,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-1.48,-3.711,2.231,,0.387,G,A,,0.03,,,,OPP,-1.365,0.18783,0.0037961,0.935455 E1_Ubiquitin_R42M,E1_Ubiquitin_42,Uba1,E1_Ubiquitin,P0CG63,0.935455,NO,42,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.302,-4.35,3.048,,0.244,E,B,,-0.54,,,,PBH,-1.24667,0.18783,0.00224033,0.935455 beta-lactamase_A77R,beta-lactamase_77,TEM-1,beta-lactamase,P62593,0.935466,NO,77,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.234,-3.891,2.657,4.75777,0.039,H,A,0.52,-0.56,1.708,,64.34,OHH,-1.294,0.221079,0.00282362,0.935466 beta-lactamase_0_R91V,beta-lactamase_0_91,TEM-1,beta-lactamase_0,P62593,0.935479,NO,91,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.392,-3.661,2.269,,0.444,,B,1.2,0.96,4.557,,50.35,OBB,-1.73367,0.0500837,0.00380226,0.935479 Ubiquitin_A28Y,Ubiquitin_28,Uba1,Ubiquitin,P0CG48,0.935484,NO,28,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.895,-4.336,2.441,4.73736,0.369,H,A,,-0.11,,,,BHB,-1.47667,0.205827,0.000842053,0.935484 Ubiquitin_D21G,Ubiquitin_21,Uba1,Ubiquitin,P0CG48,0.935484,NO,21,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.193,-3.209,2.016,4.96432,0.165,,B,0.23,-0.53,1.013,,71.82,PAP,-1.35867,0.205827,0.000465257,0.935484 Ubiquitin_D32A,Ubiquitin_32,Uba1,Ubiquitin,P0CG48,0.935484,NO,32,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.451,-2.58,1.129,4.96502,0.835,H,A,,1.4,,,,PAB,-1.47067,0.205827,0.000758819,0.935484 Ubiquitin_D58E,Ubiquitin_58,Uba1,Ubiquitin,P0CG48,0.935484,NO,58,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.622,-2.484,0.862,5.06391,0.457,G,A,,-0.54,,,,PAH,-1.60267,0.205827,0.000639847,0.935484 Ubiquitin_E34H,Ubiquitin_34,Uba1,Ubiquitin,P0CG48,0.935484,NO,34,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.294,-4.439,3.145,5.02178,0.406,H,A,1.62,0.6,1.295,,35.62,BAO,-1.24933,0.205827,0.000686048,0.935484 Ubiquitin_E51F,Ubiquitin_51,Uba1,Ubiquitin,P0CG48,0.935484,NO,51,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.534,-4.333,2.799,5.36711,0.545,,B,,0.72,,,,HAA,-1.357,0.205827,0.000868134,0.935484 Ubiquitin_F45M,Ubiquitin_45,Uba1,Ubiquitin,P0CG48,0.935484,NO,45,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.322,-4.272,2.95,4.80693,0.26,E,B,1.62,-0.99,1.531,,53.87,HHH,-1.55267,0.205827,0.000470401,0.935484 Ubiquitin_F4L,Ubiquitin_4,Uba1,Ubiquitin,P0CG48,0.935484,NO,4,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.534,-2.418,0.884,4.77459,0.059,E,B,,-0.46,,,,HHH,-1.504,0.205827,0.000805043,0.935484 Ubiquitin_G35S,Ubiquitin_35,Uba1,Ubiquitin,P0CG48,0.935484,NO,35,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.171,-2.596,1.425,4.96213,0.713,,L,,0.2,,,,AOH,-1.314,0.205827,0.000648878,0.935484 Ubiquitin_K11G,Ubiquitin_11,Uba1,Ubiquitin,P0CG48,0.935484,NO,11,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.354,-3.392,2.038,5.16813,0.401,,B,2.81,0.84,0.335,,25.84,OBP,-1.346,0.205827,0.000535553,0.935484 Ubiquitin_K11H,Ubiquitin_11,Uba1,Ubiquitin,P0CG48,0.935484,NO,11,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.354,-2.895,1.541,5.16813,0.401,,B,2.81,0.84,0.335,,25.84,OBP,-1.346,0.205827,0.000535553,0.935484 Ubiquitin_K33L,Ubiquitin_33,Uba1,Ubiquitin,P0CG48,0.935484,NO,33,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.283,-2.245,0.962,5.08526,0.64,H,A,1.82,1.2,1.509,,51.09,ABA,-1.34267,0.205827,0.000712743,0.935484 Ubiquitin_K33M,Ubiquitin_33,Uba1,Ubiquitin,P0CG48,0.935484,NO,33,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.283,-2.997,1.714,5.08526,0.64,H,A,1.82,1.2,1.509,,51.09,ABA,-1.34267,0.205827,0.000712743,0.935484 Ubiquitin_K63F,Ubiquitin_63,Uba1,Ubiquitin,P0CG48,0.935484,NO,63,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.635,-4.38,2.745,5.08297,0.721,T,B,,0.59,,,,PBA,-1.74467,0.205827,0.000607964,0.935484 Ubiquitin_L15Q,Ubiquitin_15,Uba1,Ubiquitin,P0CG48,0.935484,NO,15,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.082,-4.185,3.103,5.14718,0.029,E,B,1.16,-0.53,0.936,,38.69,PHA,-1.40833,0.205827,0.000519738,0.935484 Ubiquitin_L69F,Ubiquitin_69,Uba1,Ubiquitin,P0CG48,0.935484,NO,69,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.445,-2.951,1.506,4.75624,0.051,E,B,2.89,-0.94,7.106,,34.31,BHH,-1.72933,0.205827,0.000919136,0.935484 Ubiquitin_L69I,Ubiquitin_69,Uba1,Ubiquitin,P0CG48,0.935484,NO,69,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.445,-2.708,1.263,4.75624,0.051,E,B,2.89,-0.94,7.106,,34.31,BHH,-1.72933,0.205827,0.000919136,0.935484 Ubiquitin_L8I,Ubiquitin_8,Uba1,Ubiquitin,P0CG48,0.935484,NO,8,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.723,-2.768,1.045,5.28016,0.664,T,A,0.08,-0.34,0.664,,29.05,PHP,-1.51567,0.205827,0.000726165,0.935484 Ubiquitin_N25F,Ubiquitin_25,Uba1,Ubiquitin,P0CG48,0.935484,NO,25,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-1.95,-4.283,2.333,4.76563,0.444,H,A,0.09,0,2.3,,31.09,APH,-1.741,0.205827,0.00071919,0.935484 Ubiquitin_Q40G,Ubiquitin_40,Uba1,Ubiquitin,P0CG48,0.935484,NO,40,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-1.752,-3.461,1.709,4.7807,0.387,G,A,,0.03,,,,APP,-1.62433,0.205827,0.000619089,0.935484 Ubiquitin_Q49S,Ubiquitin_49,Uba1,Ubiquitin,P0CG48,0.935484,NO,49,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-1.941,-2.768,0.827,5.05026,0.403,E,B,,-0.59,,,,BPH,-1.49467,0.205827,0.000613067,0.935484 Ubiquitin_S57W,Ubiquitin_57,Uba1,Ubiquitin,P0CG48,0.935484,NO,57,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.879,-5.449,3.57,4.65125,0.456,G,A,,-0.42,,,,HPA,-1.60833,0.205827,0.000948086,0.935484 Ubiquitin_T22G,Ubiquitin_22,Uba1,Ubiquitin,P0CG48,0.935484,NO,22,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.344,-3.286,1.942,4.54389,0.237,B,B,,-0.75,,,,APH,-1.28733,0.205827,0.000535592,0.935484 Ubiquitin_T22V,Ubiquitin_22,Uba1,Ubiquitin,P0CG48,0.935484,NO,22,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.344,-3.21,1.866,4.54389,0.237,B,B,,-0.75,,,,APH,-1.28733,0.205827,0.000535592,0.935484 Ubiquitin_T9M,Ubiquitin_9,Uba1,Ubiquitin,P0CG48,0.935484,NO,9,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.409,-4.5,3.091,5.24336,0.777,T,A,2.12,-0.12,2.705,,29.93,HPO,-1.50933,0.205827,0.000630716,0.935484 Ubiquitin_T9N,Ubiquitin_9,Uba1,Ubiquitin,P0CG48,0.935484,NO,9,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.409,-2.672,1.263,5.24336,0.777,T,A,2.12,-0.12,2.705,,29.93,HPO,-1.50933,0.205827,0.000630716,0.935484 Ubiquitin_V17P,Ubiquitin_17,Uba1,Ubiquitin,P0CG48,0.935484,NO,17,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.314,-3.973,2.659,5.26282,0.017,,B,2.78,-0.77,3.239,,71.82,AHA,-1.51833,0.205827,0.000659638,0.935484 Pab1_N192H,Pab1_192,Pab1,Pab1,P04147,0.935492,NO,192,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-1.079,-3.822,2.743,,0.619,T,l,,2.28,,,,HPO,-1.231,0.175299,0.000273498,0.935492 beta-lactamase_2500_T139D,beta-lactamase_2500_139,TEM-1,beta-lactamase_2500,P62593,0.935521,NO,139,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.901,-3.596,1.695,,0.216,H,A,0.22,0.39,2.256,,77.62,PPH,-2.04667,0.361275,0.00441837,0.935521 Pab1_K140G,Pab1_140,Pab1,Pab1,P04147,0.935555,NO,140,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.083,-3.175,2.092,,0.345,H,A,,-0.73,,,,PBH,-1.20767,0.175299,0.000337366,0.935555 beta-lactamase_H5L,beta-lactamase_5,TEM-1,beta-lactamase,P62593,0.935572,NO,5,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-2.698,-3.193,0.495,,,,,,,1.865,,72.73,PBH,-2.36967,0.221079,0.00292712,0.935572 PSD95pdz3_S350P,PSD95pdz3_350,PSD95pdz3,PSD95pdz3,P31016,0.935639,NO,350,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.519,-3.336,1.817,4.97629,,,,,25.01,,,,HPO,-1.29133,0.0758425,0.000704883,0.935639 beta-lactamase_I140V,beta-lactamase_140,TEM-1,beta-lactamase,P62593,0.935651,NO,140,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.733,-1.662,-0.071,5.29918,0.128,H,A,1,0.41,1.16,,73.08,PHO,-1.48733,0.221079,0.00597777,0.935651 beta-lactamase_39_D207Q,beta-lactamase_39_207,TEM-1,beta-lactamase_39,P62593,0.935669,NO,207,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.064,-2.209,0.145,,0.409,H,A,0.75,0.12,14.511,14.511,77.62,HAH,-1.77033,0.0495842,0.00592942,0.935669 beta-lactamase_T193D,beta-lactamase_193,TEM-1,beta-lactamase,P62593,0.935701,NO,193,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.914,-3.815,1.901,5.67952,0.439,H,a,0.3,0.33,1.863,,63.99,HPO,-1.52133,0.221079,0.00482669,0.935701 beta-lactamase_0_A200F,beta-lactamase_0_200,TEM-1,beta-lactamase_0,P62593,0.935752,NO,200,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.878,-4.397,2.519,,0.757,H,A,0.46,-0.19,16.368,16.368,77.62,HHP,-2.001,0.0500837,0.0060056,0.935752 beta-lactamase_2500_S80D,beta-lactamase_2500_80,TEM-1,beta-lactamase_2500,P62593,0.935757,NO,80,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.029,-2.7,0.671,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.361275,0.00565569,0.935757 beta-lactamase_0_M209H,beta-lactamase_0_209,TEM-1,beta-lactamase_0,P62593,0.935768,NO,209,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.442,-4.813,3.371,,,H,A,0.55,-0.97,3.876,,64.69,HHA,-1.52633,0.0500837,0.00625021,0.935768 beta-lactamase_2500_K190F,beta-lactamase_2500_190,TEM-1,beta-lactamase_2500,P62593,0.935775,NO,190,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.994,-4.396,2.402,,0.371,H,A,2.34,0.16,29.753,29.753,77.62,BBH,-1.64167,0.361275,0.00574527,0.935775 kka2_1:8_H135C,kka2_1:8_135,Kka2,kka2_1:8,P00552,0.935791,NO,135,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-1.331,-5.106,3.775,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.100394,0.00532566,0.935791 kka2_1:8_H135C,kka2_1:8_135,Kka2,kka2_1:8,P00552,0.935791,NO,135,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-1.331,-5.106,3.775,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.100394,0.00532566,0.935791 beta-lactamase_0_R118N,beta-lactamase_0_118,TEM-1,beta-lactamase_0,P62593,0.935795,NO,118,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.413,-3.711,1.298,,0.457,H,A,1.2,1.39,3.961,,77.62,HBA,-1.785,0.0500837,0.00538794,0.935795 beta-lactamase_0_Q37H,beta-lactamase_0_37,TEM-1,beta-lactamase_0,P62593,0.935817,NO,37,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.134,-3.314,1.18,,0.613,H,A,0.64,1.98,4.001,,73.08,APH,-2.06967,0.0500837,0.00425833,0.935817 beta-lactamase_625_Q204G,beta-lactamase_625_204,TEM-1,beta-lactamase_625,P62593,0.935828,NO,204,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-1.382,-3.474,2.092,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.213352,0.00364106,0.935828 kka2_1:8_Y257W,kka2_1:8_257,Kka2,kka2_1:8,P00552,0.935831,NO,257,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-1.064,-4.353,3.289,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.100394,0.0148191,0.935831 kka2_1:8_Y257W,kka2_1:8_257,Kka2,kka2_1:8,P00552,0.935831,NO,257,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-1.064,-4.353,3.289,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.100394,0.0148191,0.935831 PSD95pdz3_S339M,PSD95pdz3_339,PSD95pdz3,PSD95pdz3,P31016,0.935839,NO,339,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.519,-4.162,2.643,5.34493,,,,,12.2167,,,,HPH,-1.55767,0.0758425,0.00084982,0.935839 kka2_1:8_D180Y,kka2_1:8_180,Kka2,kka2_1:8,P00552,0.935851,NO,180,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.416,-3.544,1.128,,1.03,S,a,0.75,1.5,14.668,14.668,71.59,OAO,-2.02933,0.100394,0.00756412,0.935851 kka2_1:8_D180Y,kka2_1:8_180,Kka2,kka2_1:8,P00552,0.935851,NO,180,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.416,-3.544,1.128,,1.03,S,a,0.75,1.5,14.668,14.668,71.59,OAO,-2.02933,0.100394,0.00756412,0.935851 beta-lactamase_R41V,beta-lactamase_41,TEM-1,beta-lactamase,P62593,0.935862,NO,41,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-0.942,-3.751,2.809,5.69185,0.321,E,B,0.91,-0.07,4.357,,65.03,HBH,-1.30267,0.221079,0.00123327,0.935862 Pab1_L153F,Pab1_153,Pab1,Pab1,P04147,0.935884,NO,153,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.039,-3.434,2.395,,0.46,E,A,,-0.95,,,,HHP,-1.17667,0.175299,0.000321212,0.935884 beta-lactamase_0_Q97D,beta-lactamase_0_97,TEM-1,beta-lactamase_0,P62593,0.935899,NO,97,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.072,-3.567,1.495,,0.823,G,A,0.64,2.42,16.954,16.954,77.62,PPP,-2.43833,0.0500837,0.0045116,0.935899 beta-lactamase_39_D231N,beta-lactamase_39_231,TEM-1,beta-lactamase_39,P62593,0.935947,NO,231,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.816,-3.272,2.456,,,E,B,0.75,-1.06,0.462,,65.38,HAB,-0.994,0.0495842,0.00107395,0.935947 beta-lactamase_2500_A230C,beta-lactamase_2500_230,TEM-1,beta-lactamase_2500,P62593,0.935957,NO,230,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.154,-4.695,3.541,,0.01,E,B,0.46,-1.17,1.171,,50,HHA,-1.079,0.361275,0.00516841,0.935957 kka2_1:4_L184F,kka2_1:4_184,Kka2,kka2_1:4,P00552,0.93596,NO,184,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.496,-2.947,1.451,,0.489,E,B,1.59,-0.06,4.495,,63.26,AHH,-1.24833,0.168804,0.00518742,0.93596 beta-lactamase_39_Y95N,beta-lactamase_39_95,TEM-1,beta-lactamase_39,P62593,0.93597,NO,95,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-1.715,-4.149,2.434,,0.122,,b,0.21,-0.37,2.341,,77.62,BHP,-2.16167,0.0495842,0.00479449,0.93597 Pab1_E181S,Pab1_181,Pab1,Pab1,P04147,0.936033,NO,181,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.767,-3.006,1.239,,,,,,,1.395,,73.83,BAH,-1.575,0.175299,0.00107557,0.936033 Pab1_G188D,Pab1_188,Pab1,Pab1,P04147,0.936037,NO,188,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.809,-3.286,2.477,,0.379,E,g,,2.18,,,,POH,-1.14633,0.175299,0.000280911,0.936037 PSD95pdz3_D332V,PSD95pdz3_332,PSD95pdz3,PSD95pdz3,P31016,0.936057,NO,332,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.264,-3.435,2.171,6.09878,,,,,48.762,,,,AAO,-1.22533,0.0758425,0.000937818,0.936057 kka2_1:4_M116F,kka2_1:4_116,Kka2,kka2_1:4,P00552,0.936065,NO,116,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-2.482,-3.107,0.625,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.168804,0.00745147,0.936065 beta-lactamase_S57F,beta-lactamase_57,TEM-1,beta-lactamase,P62593,0.936067,NO,57,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.918,-4.274,2.356,5.64201,0.352,E,B,0.25,-0.18,1.971,,72.73,APH,-2.29167,0.221079,0.00492804,0.936067 beta-lactamase_0_G39A,beta-lactamase_0_39,TEM-1,beta-lactamase_0,P62593,0.936082,NO,39,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.864,-2.728,0.864,,0.701,T,L,0.29,0.47,4.111,,77.62,HOH,-1.53633,0.0500837,0.00487611,0.936082 beta-lactamase_156_G141W,beta-lactamase_156_141,TEM-1,beta-lactamase_156,P62593,0.9361,NO,141,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.828,-5.233,4.405,,0.575,T,l,0.29,-0.28,0.198,,64.69,HOO,-1.08933,0.111618,0.0012419,0.9361 Pab1_A182L,Pab1_182,Pab1,Pab1,P04147,0.936124,NO,182,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.013,-2.95,1.937,,,H,A,0.17,0.79,,,,AHH,-1.36067,0.175299,0.000289034,0.936124 kka2_1:4_A14W,kka2_1:4_14,Kka2,kka2_1:4,P00552,0.936151,NO,14,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.837,-5.518,3.681,,0.728,G,A,0.46,0.7,0.36,,71.59,HHH,-1.82567,0.168804,0.00706614,0.936151 beta-lactamase_2500_R81Q,beta-lactamase_2500_81,TEM-1,beta-lactamase_2500,P62593,0.936159,NO,81,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.466,-2.446,0.98,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.361275,0.00499763,0.936159 beta-lactamase_0_N173H,beta-lactamase_0_173,TEM-1,beta-lactamase_0,P62593,0.936163,NO,173,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-2.663,-4.635,1.972,,1.044,T,l,0.61,1.25,1.133,,77.62,OPA,-1.46633,0.0500837,0.0033769,0.936163 kka2_1:4_F206V,kka2_1:4_206,Kka2,kka2_1:4,P00552,0.936177,NO,206,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.349,-2.691,1.342,,0.006,E,B,0.58,-1.21,1.342,,63.64,OHH,-1.04,0.168804,0.00936868,0.936177 kka2_1:4_T28S,kka2_1:4_28,Kka2,kka2_1:4,P00552,0.936188,NO,28,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.883,-2.337,0.454,,0.353,S,B,0.82,2.02,4.415,,63.64,PPH,-1.74467,0.168804,0.00743084,0.936188 kka2_1:2_A64V,kka2_1:2_64,Kka2,kka2_1:2,P00552,0.93621,NO,64,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.496,-1.905,0.409,,0.039,H,A,0.46,-0.57,14.509,14.509,56.06,AHH,-1.334,0.295029,0.00705578,0.93621 beta-lactamase_G251L,beta-lactamase_251,TEM-1,beta-lactamase,P62593,0.936229,NO,251,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.907,-2.974,1.067,5.33865,0.506,T,l,0.73,0.17,10.663,,65.38,AOB,-2.06067,0.221079,0.00733416,0.936229 kka2_1:8_Y244S,kka2_1:8_244,Kka2,kka2_1:8,P00552,0.93623,NO,244,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-0.775,-3.639,2.864,,0.066,H,A,1.25,-0.64,,,,HHO,-1.41267,0.100394,0.00453187,0.93623 kka2_1:8_Y244S,kka2_1:8_244,Kka2,kka2_1:8,P00552,0.93623,NO,244,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-0.775,-3.639,2.864,,0.066,H,A,1.25,-0.64,,,,HHO,-1.41267,0.100394,0.00453187,0.93623 PSD95pdz3_I336T,PSD95pdz3_336,PSD95pdz3,PSD95pdz3,P31016,0.936231,NO,336,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.63,-3.103,1.473,5.11321,,,,,13.6363,,,,OHH,-1.38733,0.0758425,0.000887923,0.936231 kka2_1:4_A191G,kka2_1:4_191,Kka2,kka2_1:4,P00552,0.936302,NO,191,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.831,-3.024,2.193,,,.,b,0.46,-0.94,2.046,,50,AHO,-0.868667,0.168804,0.00338807,0.936302 Pab1_K140W,Pab1_140,Pab1,Pab1,P04147,0.936319,NO,140,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.083,-5.14,4.057,,0.345,H,A,,-0.73,,,,PBH,-1.20767,0.175299,0.000337366,0.936319 beta-lactamase_39_D48P,beta-lactamase_39_48,TEM-1,beta-lactamase_39,P62593,0.936325,NO,48,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.101,-3.766,2.665,,0.189,E,B,0.75,0.21,0.735,,50.35,HAH,-1.62467,0.0495842,0.0027273,0.936325 beta-lactamase_0_V260P,beta-lactamase_0_260,TEM-1,beta-lactamase_0,P62593,0.936329,NO,260,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.0500837,0.00471757,0.936329 kka2_1:4_L93F,kka2_1:4_93,Kka2,kka2_1:4,P00552,0.936357,NO,93,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.815,-3.719,2.904,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.168804,0.00131498,0.936357 beta-lactamase_G226C,beta-lactamase_226,TEM-1,beta-lactamase,P62593,0.936386,NO,226,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.461,-3.342,1.881,5.70682,0.701,T,l,0.77,-0.25,3.199,,74.48,HOH,-1.42933,0.221079,0.00665294,0.936386 beta-lactamase_L73P,beta-lactamase_73,TEM-1,beta-lactamase,P62593,0.936396,NO,73,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.507,-2.751,1.244,5.84139,,H,A,1.75,-0.64,2.09,,67.83,HHH,-1.487,0.221079,0.00488983,0.936396 beta-lactamase_39_R239K,beta-lactamase_39_239,TEM-1,beta-lactamase_39,P62593,0.936437,NO,239,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.0495842,0.00213852,0.936437 beta-lactamase_39_D48F,beta-lactamase_39_48,TEM-1,beta-lactamase_39,P62593,0.936452,NO,48,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.101,-4.285,3.184,,0.189,E,B,0.75,0.21,0.735,,50.35,HAH,-1.62467,0.0495842,0.0027273,0.936452 gb1_K236G,gb1_236,gb1,gb1,P06654,0.936516,NO,236,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-2.119,-2.972,0.853,,,,,,,1.083,,45.54,OBP,-1.758,0.177985,0.00255408,0.936516 beta-lactamase_0_M66T,beta-lactamase_0_66,TEM-1,beta-lactamase_0,P62593,0.936518,NO,66,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.362,-3.498,2.136,,0.013,,A,0.55,-0.7,1.204,,73.08,OHH,-1.49567,0.0500837,0.00412876,0.936518 beta-lactamase_0_R257S,beta-lactamase_0_257,TEM-1,beta-lactamase_0,P62593,0.936518,NO,257,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.0500837,0.00756629,0.936518 beta-lactamase_2500_P255H,beta-lactamase_2500_255,TEM-1,beta-lactamase_2500,P62593,0.936541,NO,255,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.361275,0.00499612,0.936541 kka2_1:4_W15M,kka2_1:4_15,Kka2,kka2_1:4,P00552,0.936567,NO,15,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-1.392,-4.272,2.88,,0.01,G,A,0.47,0.15,0.943,,52.27,HHH,-2.10533,0.168804,0.00585505,0.936567 beta-lactamase_156_P105C,beta-lactamase_156_105,TEM-1,beta-lactamase_156,P62593,0.936572,NO,105,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.813,-5.05,4.237,,0.226,T,A,0.52,0.8,1.154,,63.29,POH,-1.01533,0.111618,0.0011981,0.936572 Pab1_G163W,Pab1_163,Pab1,Pab1,P04147,0.936628,NO,163,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.809,-4.915,4.106,,0.356,B,g,,0.55,,,,POB,-1.80667,0.175299,0.00030953,0.936628 beta-lactamase_0_G194V,beta-lactamase_0_194,TEM-1,beta-lactamase_0,P62593,0.936638,NO,194,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.396,-3.736,2.34,,0.276,S,b,0.29,0.36,3.017,,67.83,POA,-1.832,0.0500837,0.00392163,0.936638 WW_domain_A175G,WW_domain_175,Yap65,WW_domain,P46937,0.936649,NO,175,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.631,-3.022,1.391,6.69537,,,,,,6.257,,83.93,OHO,-1.30033,0.153962,0.00326874,0.936649 beta-lactamase_2500_G253T,beta-lactamase_2500_253,TEM-1,beta-lactamase_2500,P62593,0.936653,NO,253,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.361275,0.00786358,0.936653 beta-lactamase_0_T158Q,beta-lactamase_0_158,TEM-1,beta-lactamase_0,P62593,0.936661,NO,158,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.116,-3.908,2.792,,0.036,,B,0.22,-0.85,1.041,,69.58,HPB,-1.269,0.0500837,0.00341825,0.936661 beta-lactamase_156_P143R,beta-lactamase_156_143,TEM-1,beta-lactamase_156,P62593,0.936661,NO,143,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.967,-3.999,3.032,,0.075,H,A,0.52,-0.37,0.479,,66.78,OOB,-1.354,0.111618,0.00114551,0.936661 beta-lactamase_0_A124V,beta-lactamase_0_124,TEM-1,beta-lactamase_0,P62593,0.936675,NO,124,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.181,-2.519,1.338,,,H,A,0.46,-0.9,1.876,,64.34,HHH,-1.152,0.0500837,0.00481399,0.936675 beta-lactamase_0_S221P,beta-lactamase_0_221,TEM-1,beta-lactamase_0,P62593,0.936704,NO,221,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.754,-3.814,2.06,,0.624,H,A,0.27,-0.2,2.914,,74.48,BPH,-1.59967,0.0500837,0.0046094,0.936704 beta-lactamase_A148W,beta-lactamase_148,TEM-1,beta-lactamase,P62593,0.936719,NO,148,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.757,-5.497,3.74,5.28111,0.379,H,A,0.52,-0.55,2.117,,72.73,PHH,-1.40167,0.221079,0.00547053,0.936719 beta-lactamase_F17H,beta-lactamase_17,TEM-1,beta-lactamase,P62593,0.936719,NO,17,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-2.337,-4.785,2.448,,,,,,,2.192,,67.83,HHO,-2.17733,0.221079,0.00216499,0.936719 beta-lactamase_F6Q,beta-lactamase_6,TEM-1,beta-lactamase,P62593,0.936719,NO,6,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.847,-4.222,2.375,,,,,,,1.276,,67.83,BHB,-2.076,0.221079,0.00261627,0.936719 beta-lactamase_G226A,beta-lactamase_226,TEM-1,beta-lactamase,P62593,0.936719,NO,226,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.461,-2.638,1.177,5.70682,0.701,T,l,0.77,-0.25,3.199,,74.48,HOH,-1.42933,0.221079,0.00665294,0.936719 beta-lactamase_G39T,beta-lactamase_39,TEM-1,beta-lactamase,P62593,0.936719,NO,39,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.864,-2.931,1.067,5.35574,0.701,T,L,0.23,0.47,29.926,29.926,77.62,HOH,-1.53633,0.221079,0.00487611,0.936719 beta-lactamase_L100V,beta-lactamase_100,TEM-1,beta-lactamase,P62593,0.936719,NO,100,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.218,-2.049,0.831,5.60291,0.343,,B,1.3,0.13,1.173,,63.29,AHH,-1.23467,0.221079,0.00413885,0.936719 beta-lactamase_L49A,beta-lactamase_49,TEM-1,beta-lactamase,P62593,0.936719,NO,49,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.897,-3.125,1.228,5.86005,0.131,T,A,1.3,0.04,3.112,,64.69,AHP,-1.99233,0.221079,0.00401477,0.936719 beta-lactamase_Q203Y,beta-lactamase_203,TEM-1,beta-lactamase,P62593,0.936719,NO,203,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.168,-4.35,2.182,5.65296,0.47,H,A,0.12,-0.38,1.66,,65.38,BPP,-1.614,0.221079,0.00631514,0.936719 beta-lactamase_R159T,beta-lactamase_159,TEM-1,beta-lactamase,P62593,0.936719,NO,159,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-0.94,-3.47,2.53,5.64971,0.316,,B,0.68,-0.55,1.172,,64.34,PBH,-1.011,0.221079,0.00108472,0.936719 beta-lactamase_R162S,beta-lactamase_162,TEM-1,beta-lactamase,P62593,0.936719,NO,162,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.016,-3.456,2.44,5.34456,0.124,S,B,0.68,-0.37,31.656,31.656,64.69,ABH,-1.25,0.221079,0.000561334,0.936719 beta-lactamase_S51K,beta-lactamase_51,TEM-1,beta-lactamase,P62593,0.936719,NO,51,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.526,-3.459,1.933,5.06164,0.496,T,A,0.25,0.26,1.699,,72.73,PPO,-1.88467,0.221079,0.00504821,0.936719 beta-lactamase_T262K,beta-lactamase_262,TEM-1,beta-lactamase,P62593,0.936719,NO,262,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.332,-3.384,2.052,5.06002,0.108,E,B,0.3,-0.55,1.423,,67.83,PPO,-2.081,0.221079,0.00853516,0.936719 beta-lactamase_0_A148Y,beta-lactamase_0_148,TEM-1,beta-lactamase_0,P62593,0.936729,NO,148,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.757,-4.336,2.579,,0.379,H,A,0.46,-0.55,19.42,19.42,72.73,PHH,-1.40167,0.0500837,0.00547053,0.936729 beta-lactamase_39_D252K,beta-lactamase_39_252,TEM-1,beta-lactamase_39,P62593,0.936732,NO,252,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.94,-3.575,1.635,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.0495842,0.00575769,0.936732 WW_domain_S183F,WW_domain_183,Yap65,WW_domain,P46937,0.936734,NO,183,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.95,-4.136,2.186,5.35576,,,,,,1.594,,83.93,PPP,-1.48733,0.153962,0.00445513,0.936734 beta-lactamase_2500_A170W,beta-lactamase_2500_170,TEM-1,beta-lactamase_2500,P62593,0.936738,NO,170,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.237,-5.233,3.996,,0.126,,L,0.46,-0.35,2.427,,64.69,AHH,-1.63267,0.361275,0.00431903,0.936738 kka2_1:8_L57W,kka2_1:8_57,Kka2,kka2_1:8,P00552,0.936742,NO,57,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.898,-3.389,1.491,,0.343,T,A,0.55,0.98,13.359,13.359,52.65,HHP,-2.20733,0.100394,0.00723769,0.936742 kka2_1:8_L57W,kka2_1:8_57,Kka2,kka2_1:8,P00552,0.936742,NO,57,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.898,-3.389,1.491,,0.343,T,A,0.55,0.98,13.359,13.359,52.65,HHP,-2.20733,0.100394,0.00723769,0.936742 beta-lactamase_39_M180Y,beta-lactamase_39_180,TEM-1,beta-lactamase_39,P62593,0.936757,NO,180,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-2.795,-2.93,0.135,,0.242,,B,0.55,-0.94,3.579,,77.62,PHO,-1.56433,0.0495842,0.00552048,0.936757 beta-lactamase_625_A268P,beta-lactamase_625_268,TEM-1,beta-lactamase_625,P62593,0.936759,NO,268,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.213352,0.0102525,0.936759 beta-lactamase_0_M153D,beta-lactamase_0_153,TEM-1,beta-lactamase_0,P62593,0.936798,NO,153,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-3.193,-3.931,0.738,,0.14,T,A,0.55,-0.11,3.826,,77.62,PHO,-2.25767,0.0500837,0.00509109,0.936798 beta-lactamase_0_E164H,beta-lactamase_0_164,TEM-1,beta-lactamase_0,P62593,0.93681,NO,164,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-0.948,-4.339,3.391,,0.011,T,B,1.04,-0.4,1.011,,64.69,HAO,-1.388,0.0500837,0.00137286,0.93681 PSD95pdz3_V328L,PSD95pdz3_328,PSD95pdz3,PSD95pdz3,P31016,0.936817,NO,328,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.465,-2.365,0.9,5.28275,,,,,16.8775,,,,HHO,-1.36767,0.0758425,0.000986706,0.936817 kka2_1:8_D127G,kka2_1:8_127,Kka2,kka2_1:8,P00552,0.936848,NO,127,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.364,-3.377,2.013,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.100394,0.00660501,0.936848 kka2_1:8_D127G,kka2_1:8_127,Kka2,kka2_1:8,P00552,0.936848,NO,127,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.364,-3.377,2.013,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.100394,0.00660501,0.936848 PSD95pdz3_D348F,PSD95pdz3_348,PSD95pdz3,PSD95pdz3,P31016,0.93688,NO,348,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.264,-3.974,2.71,5.02473,,,,,16.8925,,,,HAH,-1.306,0.0758425,0.000731866,0.93688 kka2_1:1_V16H,kka2_1:1_16,Kka2,kka2_1:1,P00552,0.936888,NO,16,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-3.087,-3.512,0.425,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.520039,0.00694011,0.936888 beta-lactamase_0_P105A,beta-lactamase_0_105,TEM-1,beta-lactamase_0,P62593,0.936938,NO,105,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.813,-3.041,2.228,,0.226,T,A,0.52,0.8,3.48,,63.29,POH,-1.01533,0.0500837,0.0011981,0.936938 beta-lactamase_2500_R159K,beta-lactamase_2500_159,TEM-1,beta-lactamase_2500,P62593,0.936943,NO,159,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-0.94,-2.865,1.925,,0.316,,B,1.2,-0.55,2.341,,64.34,PBH,-1.011,0.361275,0.00108472,0.936943 Pab1_F149L,Pab1_149,Pab1,Pab1,P04147,0.936982,NO,149,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.149,-2.725,1.576,,0.183,T,A,1.33,1.09,,,,HHO,-1.27767,0.175299,0.000325688,0.936982 PSD95pdz3_F337I,PSD95pdz3_337,PSD95pdz3,PSD95pdz3,P31016,0.937054,NO,337,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.524,-3.017,1.493,5.22838,,,,,13.4936,,,,HHH,-1.59467,0.0758425,0.000875287,0.937054 kka2_1:1_Q4K,kka2_1:1_4,Kka2,kka2_1:1,P00552,0.937058,NO,4,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.361,-3.145,0.784,,,,,,,5.615,,71.59,APA,-1.95533,0.520039,0.00239179,0.937058 beta-lactamase_39_V117Q,beta-lactamase_39_117,TEM-1,beta-lactamase_39,P62593,0.937085,NO,117,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.53,-4.247,2.717,,,H,A,0.44,-0.34,1.182,,65.03,PHB,-1.741,0.0495842,0.00467906,0.937085 beta-lactamase_39_Y103K,beta-lactamase_39_103,TEM-1,beta-lactamase_39,P62593,0.93709,NO,103,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-1.33,-3.666,2.336,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.0495842,0.00443048,0.93709 beta-lactamase_156_P172I,beta-lactamase_156_172,TEM-1,beta-lactamase_156,P62593,0.937113,NO,172,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.998,-3.854,2.856,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.111618,0.00312594,0.937113 PSD95pdz3_E373Q,PSD95pdz3_373,PSD95pdz3,PSD95pdz3,P31016,0.937135,NO,373,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.404,-2.906,1.502,5.79743,,,,,27.9833,,,,BAP,-1.57667,0.0758425,0.000387698,0.937135 kka2_1:8_T72N,kka2_1:8_72,Kka2,kka2_1:8,P00552,0.937146,NO,72,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.38,-3.767,1.387,,0.784,H,A,0.22,0.29,3.603,,65.53,HPP,-2.238,0.100394,0.00750756,0.937146 kka2_1:8_T72N,kka2_1:8_72,Kka2,kka2_1:8,P00552,0.937146,NO,72,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.38,-3.767,1.387,,0.784,H,A,0.22,0.29,3.603,,65.53,HPP,-2.238,0.100394,0.00750756,0.937146 Pab1_E176S,Pab1_176,Pab1,Pab1,P04147,0.93715,NO,176,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.003,-2.432,0.429,,,,,,,,,,AAO,-2.09933,0.175299,0.00264426,0.93715 kka2_1:4_A87E,kka2_1:4_87,Kka2,kka2_1:4,P00552,0.937151,NO,87,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.917,-2.476,0.559,,1.039,S,L,0.46,1.57,22.675,22.675,65.53,AHO,-1.822,0.168804,0.00791281,0.937151 beta-lactamase_2500_L150A,beta-lactamase_2500_150,TEM-1,beta-lactamase_2500,P62593,0.937178,NO,150,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.326,-2.051,0.725,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.361275,0.00463171,0.937178 kka2_1:4_S104C,kka2_1:4_104,Kka2,kka2_1:4,P00552,0.937183,NO,104,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.436,-3.387,1.951,,0.536,T,A,0.27,-1.11,0.357,,63.64,HPP,-1.91433,0.168804,0.00555207,0.937183 beta-lactamase_2500_M270V,beta-lactamase_2500_270,TEM-1,beta-lactamase_2500,P62593,0.937196,NO,270,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.723,,,,0.422,H,A,1.59,1.15,2.029,,64.34,PHA,-1.70933,0.361275,0.00767762,0.937196 beta-lactamase_0_A230E,beta-lactamase_0_230,TEM-1,beta-lactamase_0,P62593,0.937224,NO,230,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.154,-3.566,2.412,,0.01,E,B,0.46,-1.17,2.179,,50,HHA,-1.079,0.0500837,0.00516841,0.937224 E1_Ubiquitin_R42Q,E1_Ubiquitin_42,Uba1,E1_Ubiquitin,P0CG63,0.937224,NO,42,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.302,-3.32,2.018,,0.244,E,B,,-0.54,,,,PBH,-1.24667,0.18783,0.00224033,0.937224 E1_Ubiquitin_T68P,E1_Ubiquitin_68,Uba1,E1_Ubiquitin,P0CG63,0.937224,NO,68,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,,,,,,,,,,,,,OPH,-1.039,0.18783,0.00314321,0.937224 beta-lactamase_39_A133N,beta-lactamase_39_133,TEM-1,beta-lactamase_39,P62593,0.937229,NO,133,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.186,-3.758,2.572,,,H,A,0.46,-0.86,0.373,,67.83,HHP,-0.988333,0.0495842,0.00468022,0.937229 gb1_T244Q,gb1_244,gb1,gb1,P06654,0.937231,NO,244,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.637,-3.816,2.179,,,,,,,0.202,,11.83,PPA,-1.92567,0.177985,0.00222755,0.937231 beta-lactamase_39_K213S,beta-lactamase_39_213,TEM-1,beta-lactamase_39,P62593,0.937243,NO,213,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.81,-3.351,1.541,,0.67,,A,2.34,0.29,2.648,,67.83,ABH,-1.57767,0.0495842,0.00610411,0.937243 kka2_1:8_P45T,kka2_1:8_45,Kka2,kka2_1:8,P00552,0.937246,NO,45,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.774,-2.639,0.865,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.100394,0.00590481,0.937246 kka2_1:8_P45T,kka2_1:8_45,Kka2,kka2_1:8,P00552,0.937246,NO,45,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.774,-2.639,0.865,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.100394,0.00590481,0.937246 kka2_1:8_G245S,kka2_1:8_245,Kka2,kka2_1:8,P00552,0.937286,NO,245,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.812,-3.212,2.4,,0.655,T,g,0.75,0.03,1.148,,65.53,HOH,-1.19833,0.100394,0.00683899,0.937286 kka2_1:8_G245S,kka2_1:8_245,Kka2,kka2_1:8,P00552,0.937286,NO,245,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.812,-3.212,2.4,,0.655,T,g,0.75,0.03,1.148,,65.53,HOH,-1.19833,0.100394,0.00683899,0.937286 beta-lactamase_2500_P25L,beta-lactamase_2500_25,TEM-1,beta-lactamase_2500,P62593,0.937296,NO,25,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.526,-3.586,2.06,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.361275,0.00347571,0.937296 beta-lactamase_156_A40K,beta-lactamase_156_40,TEM-1,beta-lactamase_156,P62593,0.937299,NO,40,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.402,-3.658,2.256,,0.155,S,B,0.46,0.21,1.357,,73.78,OHB,-1.40267,0.111618,0.00490026,0.937299 beta-lactamase_0_K71V,beta-lactamase_0_71,TEM-1,beta-lactamase_0,P62593,0.937311,NO,71,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-0.8,-3.529,2.729,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.0500837,0.00103192,0.937311 beta-lactamase_2500_V101D,beta-lactamase_2500_101,TEM-1,beta-lactamase_2500,P62593,0.937332,NO,101,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.295,-2.887,1.592,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.361275,0.00374492,0.937332 kka2_1:4_C209G,kka2_1:4_209,Kka2,kka2_1:4,P00552,0.937344,NO,209,C,G,CG,Special,Special,5.07,3.29388,-1.77612,159,121,75,-46,108.5,60.1,-48.4,-0.906,-3.655,2.749,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.168804,0.00260862,0.937344 beta-lactamase_0_R81A,beta-lactamase_0_81,TEM-1,beta-lactamase_0,P62593,0.937349,NO,81,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.466,-2.609,1.143,,0.218,H,A,1.2,1.66,0.332,,50,PBH,-1.60667,0.0500837,0.00499763,0.937349 kka2_1:1_A248E,kka2_1:1_248,Kka2,kka2_1:1,P00552,0.93735,NO,248,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.124,-2.197,0.073,,0.825,S,b,0.46,0.46,24.72,24.72,92.05,HHO,-2.15,0.520039,0.0125484,0.93735 Pab1_K164H,Pab1_164,Pab1,Pab1,P04147,0.937375,NO,164,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-2.298,-2.913,0.615,,,,,,,,,,OBP,-1.41767,0.175299,0.00255241,0.937375 kka2_1:8_A56I,kka2_1:8_56,Kka2,kka2_1:8,P00552,0.937386,NO,56,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.083,-3.881,1.798,,0.796,T,A,0.46,1.39,10.511,,71.59,OHH,-1.86867,0.100394,0.00717715,0.937386 kka2_1:8_A56I,kka2_1:8_56,Kka2,kka2_1:8,P00552,0.937386,NO,56,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.083,-3.881,1.798,,0.796,T,A,0.46,1.39,10.511,,71.59,OHH,-1.86867,0.100394,0.00717715,0.937386 kka2_1:4_A64T,kka2_1:4_64,Kka2,kka2_1:4,P00552,0.937391,NO,64,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.496,-2.834,1.338,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.168804,0.00705578,0.937391 beta-lactamase_39_K144R,beta-lactamase_39_144,TEM-1,beta-lactamase_39,P62593,0.937403,NO,144,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-2.388,-3.055,0.667,,0.863,H,A,2.34,1.27,14.556,14.556,77.62,OBA,-1.904,0.0495842,0.00481141,0.937403 gb1_T279H,gb1_279,gb1,gb1,P06654,0.937469,NO,279,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.32,-4.579,3.259,,,,,,,0.529,,35.71,HPH,-1.50067,0.177985,0.00421454,0.937469 beta-lactamase_L10F,beta-lactamase_10,TEM-1,beta-lactamase,P62593,0.937476,NO,10,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.623,-2.692,1.069,,,,,,,2.467,,65.38,HHH,-1.83833,0.221079,0.00296968,0.937476 beta-lactamase_2500_E119G,beta-lactamase_2500_119,TEM-1,beta-lactamase_2500,P62593,0.937477,NO,119,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.412,-2.405,0.993,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.361275,0.00386966,0.937477 beta-lactamase_0_A225T,beta-lactamase_0_225,TEM-1,beta-lactamase_0,P62593,0.937488,NO,225,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.845,-2.966,1.121,,1,T,B,0.46,-0.38,11.722,11.722,74.48,OHO,-1.39967,0.0500837,0.00465057,0.937488 beta-lactamase_T267V,beta-lactamase_267,TEM-1,beta-lactamase,P62593,0.937513,NO,267,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.308,-3.573,1.265,5.28263,0.54,,B,0.69,-0.14,0.374,,73.78,HPH,-1.9,0.221079,0.0102128,0.937513 kka2_1:2_Q100N,kka2_1:2_100,Kka2,kka2_1:2,P00552,0.937536,NO,100,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.77,-3.216,0.446,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.295029,0.0066405,0.937536 beta-lactamase_39_D48Y,beta-lactamase_39_48,TEM-1,beta-lactamase_39,P62593,0.937574,NO,48,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.101,-4.182,3.081,,0.189,E,B,0.75,0.21,0.735,,50.35,HAH,-1.62467,0.0495842,0.0027273,0.937574 kka2_1:2_G74N,kka2_1:2_74,Kka2,kka2_1:2,P00552,0.93761,NO,74,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.18,-2.406,1.226,,0.621,T,l,0.75,0.2,1.446,,64.39,POH,-1.91667,0.295029,0.00587035,0.93761 beta-lactamase_2500_S221E,beta-lactamase_2500_221,TEM-1,beta-lactamase_2500,P62593,0.937614,NO,221,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.754,-3.442,1.688,,0.624,H,A,0.27,-0.2,1.971,,74.48,BPH,-1.59967,0.361275,0.0046094,0.937614 Pab1_M189A,Pab1_189,Pab1,Pab1,P04147,0.937616,NO,189,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.406,-2.895,1.489,,0.631,E,b,,2.81,,,,OHH,-1.18,0.175299,0.000278756,0.937616 kka2_1:8_K175Q,kka2_1:8_175,Kka2,kka2_1:8,P00552,0.937626,NO,175,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-2.897,-2.736,-0.161,,0.579,H,A,2.34,0.51,15.316,15.316,71.59,HBH,-1.82333,0.100394,0.00693093,0.937626 kka2_1:8_K175Q,kka2_1:8_175,Kka2,kka2_1:8,P00552,0.937626,NO,175,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-2.897,-2.736,-0.161,,0.579,H,A,2.34,0.51,15.316,15.316,71.59,HBH,-1.82333,0.100394,0.00693093,0.937626 beta-lactamase_625_L135E,beta-lactamase_625_135,TEM-1,beta-lactamase_625,P62593,0.937636,NO,135,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.002,-3.919,2.917,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.213352,0.00244423,0.937636 beta-lactamase_0_S266Q,beta-lactamase_0_266,TEM-1,beta-lactamase_0,P62593,0.937641,NO,266,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.0500837,0.0140785,0.937641 beta-lactamase_2500_E272R,beta-lactamase_2500_272,TEM-1,beta-lactamase_2500,P62593,0.937673,NO,272,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.361275,0.00545371,0.937673 beta-lactamase_R41I,beta-lactamase_41,TEM-1,beta-lactamase,P62593,0.937677,NO,41,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-0.942,-4.008,3.066,5.69185,0.321,E,B,0.91,-0.07,4.357,,65.03,HBH,-1.30267,0.221079,0.00123327,0.937677 beta-lactamase_V21V,beta-lactamase_21,TEM-1,beta-lactamase,P62593,0.937677,NO,21,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.873,-1.873,,,,,,,,0.688,,93.01,OHH,-2.09633,0.221079,0.0028612,0.937677 beta-lactamase_0_L150N,beta-lactamase_0_150,TEM-1,beta-lactamase_0,P62593,0.937683,NO,150,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.326,-4.088,2.762,,,H,A,0.55,-0.2,2.128,,62.94,HHB,-1.86167,0.0500837,0.00463171,0.937683 beta-lactamase_2500_K213S,beta-lactamase_2500_213,TEM-1,beta-lactamase_2500,P62593,0.937713,NO,213,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.81,-3.351,1.541,,0.67,,A,2.34,0.29,1.668,,67.83,ABH,-1.57767,0.361275,0.00610411,0.937713 kka2_1:8_N200A,kka2_1:8_200,Kka2,kka2_1:8,P00552,0.937743,NO,200,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-2.446,-2.325,-0.121,,0.756,T,L,0.43,-0.08,2.528,,64.39,APO,-2.08,0.100394,0.00838549,0.937743 kka2_1:8_N200A,kka2_1:8_200,Kka2,kka2_1:8,P00552,0.937743,NO,200,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-2.446,-2.325,-0.121,,0.756,T,L,0.43,-0.08,2.528,,64.39,APO,-2.08,0.100394,0.00838549,0.937743 PSD95pdz3_P346T,PSD95pdz3_346,PSD95pdz3,PSD95pdz3,P31016,0.937746,NO,346,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.236,-3.103,1.867,5.02406,,,,,14.6629,,,,OOH,-1.18367,0.0758425,0.000758563,0.937746 kka2_1:8_I228V,kka2_1:8_228,Kka2,kka2_1:8,P00552,0.937763,NO,228,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.142,-1.946,0.804,,,H,A,1.52,-1.2,1.521,,71.59,AHH,-1.54633,0.100394,0.00458834,0.937763 kka2_1:8_I228V,kka2_1:8_228,Kka2,kka2_1:8,P00552,0.937763,NO,228,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.142,-1.946,0.804,,,H,A,1.52,-1.2,1.521,,71.59,AHH,-1.54633,0.100394,0.00458834,0.937763 kka2_1:4_L81N,kka2_1:4_81,Kka2,kka2_1:4,P00552,0.937827,NO,81,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.427,-4.237,2.81,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.168804,0.00805839,0.937827 PSD95pdz3_R354W,PSD95pdz3_354,PSD95pdz3,PSD95pdz3,P31016,0.937845,NO,354,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.582,-5.004,3.422,6.21887,,,,,23.7791,,,,HBB,-1.44833,0.0758425,0.000650924,0.937845 beta-lactamase_2500_P172F,beta-lactamase_2500_172,TEM-1,beta-lactamase_2500,P62593,0.937855,NO,172,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.998,-4.371,3.373,,0.639,T,b,0.52,0.24,4.99,,74.48,HOP,-2.03067,0.361275,0.00312594,0.937855 beta-lactamase_2500_T193E,beta-lactamase_2500_193,TEM-1,beta-lactamase_2500,P62593,0.9379,NO,193,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.914,-3.756,1.842,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.361275,0.00482669,0.9379 beta-lactamase_625_D161M,beta-lactamase_625_161,TEM-1,beta-lactamase_625,P62593,0.9379,NO,161,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.891,-4.899,4.008,,0.341,,A,0.75,-0.52,4.655,,61.19,HAB,-0.961333,0.213352,0.000897697,0.9379 beta-lactamase_S57D,beta-lactamase_57,TEM-1,beta-lactamase,P62593,0.9379,NO,57,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.918,-3.634,1.716,5.64201,0.352,E,B,0.25,-0.18,1.971,,72.73,APH,-2.29167,0.221079,0.00492804,0.9379 kka2_1:8_E169C,kka2_1:8_169,Kka2,kka2_1:8,P00552,0.9379,NO,169,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.996,-5.197,3.201,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.100394,0.00730086,0.9379 kka2_1:8_E169C,kka2_1:8_169,Kka2,kka2_1:8,P00552,0.9379,NO,169,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.996,-5.197,3.201,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.100394,0.00730086,0.9379 beta-lactamase_0_G43W,beta-lactamase_0_43,TEM-1,beta-lactamase_0,P62593,0.937942,NO,43,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.62,-5.097,4.477,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.0500837,0.00120151,0.937942 Pab1_D151C,Pab1_151,Pab1,Pab1,P04147,0.938007,NO,151,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.399,-5.063,2.664,,,,,,,,,,OAH,-1.51767,0.175299,0.00228155,0.938007 beta-lactamase_2500_W163N,beta-lactamase_2500_163,TEM-1,beta-lactamase_2500,P62593,0.938018,NO,163,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-1.843,-2.852,1.009,,0.467,,B,0.47,-0.5,32.624,32.624,63.99,BHA,-1.269,0.361275,0.00418955,0.938018 beta-lactamase_0_P143T,beta-lactamase_0_143,TEM-1,beta-lactamase_0,P62593,0.938019,NO,143,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.967,-2.616,1.649,,0.075,H,A,0.52,-0.37,11.868,11.868,66.78,OOB,-1.354,0.0500837,0.00114551,0.938019 beta-lactamase_2500_L55F,beta-lactamase_2500_55,TEM-1,beta-lactamase_2500,P62593,0.938041,NO,55,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.86,-2.527,0.667,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.361275,0.00403741,0.938041 beta-lactamase_2500_R273N,beta-lactamase_2500_273,TEM-1,beta-lactamase_2500,P62593,0.938117,NO,273,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.314,-3.744,1.43,,0.564,H,A,1.2,1.57,19.943,19.943,73.78,ABP,-1.841,0.361275,0.0077952,0.938117 beta-lactamase_0_K213H,beta-lactamase_0_213,TEM-1,beta-lactamase_0,P62593,0.938118,NO,213,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.81,-4.552,2.742,,0.67,,A,2.34,0.29,3.015,,67.83,ABH,-1.57767,0.0500837,0.00610411,0.938118 beta-lactamase_0_G114D,beta-lactamase_0_114,TEM-1,beta-lactamase_0,P62593,0.938154,NO,114,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.094,-3.551,2.457,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.0500837,0.00224919,0.938154 beta-lactamase_M67L,beta-lactamase_67,TEM-1,beta-lactamase,P62593,0.9382,NO,67,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-2.231,-2.657,0.426,4.9618,0.006,G,P,1.07,-0.81,1.463,,65.03,HHP,-1.502,0.221079,0.00409753,0.9382 beta-lactamase_R59K,beta-lactamase_59,TEM-1,beta-lactamase,P62593,0.9382,NO,59,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.345,-2.351,1.006,5.49837,0.329,S,L,0.68,-0.09,1.806,,73.08,HBO,-2.24267,0.221079,0.00318082,0.9382 beta-lactamase_625_L137C,beta-lactamase_625_137,TEM-1,beta-lactamase_625,P62593,0.938229,NO,137,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.03,-4.702,3.672,,,H,A,0.55,-0.38,1.5,,42.31,HHP,-1.58933,0.213352,0.00278599,0.938229 beta-lactamase_M127R,beta-lactamase_127,TEM-1,beta-lactamase,P62593,0.938234,NO,127,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-2.251,-2.722,0.471,5.40552,0.312,S,A,1.07,0.32,1.671,,72.73,PHP,-1.40433,0.221079,0.00437927,0.938234 beta-lactamase_0_L191G,beta-lactamase_0_191,TEM-1,beta-lactamase_0,P62593,0.938242,NO,191,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.087,-3.655,2.568,,,H,A,0.55,0.09,12.255,12.255,63.29,BHH,-1.445,0.0500837,0.00263549,0.938242 beta-lactamase_0_K144W,beta-lactamase_0_144,TEM-1,beta-lactamase_0,P62593,0.938246,NO,144,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-2.388,-5.522,3.134,,0.863,H,A,2.34,1.27,5.696,,77.62,OBA,-1.904,0.0500837,0.00481141,0.938246 beta-lactamase_0_A215Y,beta-lactamase_0_215,TEM-1,beta-lactamase_0,P62593,0.93825,NO,215,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.503,-4.339,2.836,,,,a,0.46,-0.93,0.494,,74.48,HHO,-1.42633,0.0500837,0.00544007,0.93825 beta-lactamase_S221P,beta-lactamase_221,TEM-1,beta-lactamase,P62593,0.938256,NO,221,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.754,-3.814,2.06,5.77407,0.624,H,A,0.74,-0.2,0.383,,74.48,BPH,-1.59967,0.221079,0.0046094,0.938256 beta-lactamase_39_W288S,beta-lactamase_39_288,TEM-1,beta-lactamase_39,P62593,0.938259,NO,288,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,,,,,,,,,,,,,BHO,,0.0495842,,0.938259 kka2_1:2_L243R,kka2_1:2_243,Kka2,kka2_1:2,P00552,0.938293,NO,243,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-2.651,-2.013,-0.638,,0.277,H,A,1.59,-0.67,13.165,13.165,92.05,HHH,-2.03767,0.295029,0.00884927,0.938293 beta-lactamase_A170N,beta-lactamase_170,TEM-1,beta-lactamase,P62593,0.938308,NO,170,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.237,-2.833,1.596,5.19261,0.126,,L,2.34,-0.35,2.427,,64.69,AHH,-1.63267,0.221079,0.00431903,0.938308 beta-lactamase_625_D161Q,beta-lactamase_625_161,TEM-1,beta-lactamase_625,P62593,0.938309,NO,161,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.891,-3.667,2.776,,0.341,,A,0.75,-0.52,4.655,,61.19,HAB,-0.961333,0.213352,0.000897697,0.938309 beta-lactamase_0_G114C,beta-lactamase_0_114,TEM-1,beta-lactamase_0,P62593,0.938319,NO,114,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.094,-5.014,3.92,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.0500837,0.00224919,0.938319 Pab1_A141G,Pab1_141,Pab1,Pab1,P04147,0.938334,NO,141,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.461,-2.978,1.517,,0.34,H,A,0.52,-0.27,2.15,,79.03,BHH,-1.19433,0.175299,0.00165974,0.938334 beta-lactamase_R92A,beta-lactamase_92,TEM-1,beta-lactamase,P62593,0.938338,NO,92,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.718,-2.705,0.987,5.65832,0.479,E,B,0.91,1.36,3.069,,65.38,BBH,-1.50367,0.221079,0.00429626,0.938338 beta-lactamase_0_I261G,beta-lactamase_0_261,TEM-1,beta-lactamase_0,P62593,0.938374,NO,261,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.0500837,0.0123091,0.938374 Pab1_M189T,Pab1_189,Pab1,Pab1,P04147,0.93839,NO,189,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.406,-3.239,1.833,,0.631,E,b,,2.81,,,,OHH,-1.18,0.175299,0.000278756,0.93839 beta-lactamase_39_T139L,beta-lactamase_39_139,TEM-1,beta-lactamase_39,P62593,0.9384,NO,139,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.901,-3.419,1.518,,0.216,H,A,0.22,0.39,0.421,,77.62,PPH,-2.04667,0.0495842,0.00441837,0.9384 gb1_T281Q,gb1_281,gb1,gb1,P06654,0.938415,NO,281,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.828,-3.62,1.792,,,,,,,1.038,,35.71,HPA,-1.63667,0.177985,0.00284418,0.938415 beta-lactamase_2500_I45C,beta-lactamase_2500_45,TEM-1,beta-lactamase_2500,P62593,0.938417,NO,45,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-2.421,-4.903,2.482,,,E,B,0.48,-0.3,3.793,,77.62,HHA,-2.30267,0.361275,0.00452842,0.938417 Pab1_I130C,Pab1_130,Pab1,Pab1,P04147,0.938418,NO,130,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.212,-4.454,3.242,,,E,B,1.23,0.01,,,,HHB,-1.188,0.175299,0.000351112,0.938418 beta-lactamase_A182N,beta-lactamase_182,TEM-1,beta-lactamase,P62593,0.938433,NO,182,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.777,-3.015,1.238,4.98609,0.136,H,A,0.52,-0.66,2.032,,93.01,OHH,-1.27367,0.221079,0.00559099,0.938433 beta-lactamase_I54R,beta-lactamase_54,TEM-1,beta-lactamase,P62593,0.938433,NO,54,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-2.838,-2.365,-0.473,5.40541,0.669,E,B,0.77,-0.14,3.946,,73.78,BHH,-2.337,0.221079,0.00403589,0.938433 beta-lactamase_P25D,beta-lactamase_25,TEM-1,beta-lactamase,P62593,0.938433,NO,25,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.526,-2.562,1.036,5.6134,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.221079,0.00347571,0.938433 beta-lactamase_V101E,beta-lactamase_101,TEM-1,beta-lactamase,P62593,0.938433,NO,101,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.295,-2.851,1.556,5.49045,0.342,,B,0.96,0,1.675,,73.08,HHA,-1.54367,0.221079,0.00374492,0.938433 kka2_1:8_C31T,kka2_1:8_31,Kka2,kka2_1:8,P00552,0.938457,NO,31,C,T,CT,Special,Polar,5.07,5.6,0.53,149,121,119,-2,108.5,116.1,7.6,-2.246,-3.606,1.36,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.100394,0.00681582,0.938457 kka2_1:8_C31T,kka2_1:8_31,Kka2,kka2_1:8,P00552,0.938457,NO,31,C,T,CT,Special,Polar,5.07,5.6,0.53,149,121,119,-2,108.5,116.1,7.6,-2.246,-3.606,1.36,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.100394,0.00681582,0.938457 Pab1_G167P,Pab1_167,Pab1,Pab1,P04147,0.938469,NO,167,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.223,-3.82,2.597,,0.195,S,g,,0.03,,,,BOH,-1.25133,0.175299,0.00146449,0.938469 beta-lactamase_A245G,beta-lactamase_245,TEM-1,beta-lactamase,P62593,0.938473,NO,245,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.068,-1.944,0.876,4.78972,,E,B,0.17,-0.92,0.831,,64.69,HHH,-1.58133,0.221079,0.00391032,0.938473 kka2_1:4_V198I,kka2_1:4_198,Kka2,kka2_1:4,P00552,0.938492,NO,198,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.719,-3.396,1.677,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.168804,0.00835002,0.938492 Pab1_N192F,Pab1_192,Pab1,Pab1,P04147,0.938564,NO,192,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-1.079,-4.109,3.03,,0.619,T,l,,2.28,,,,HPO,-1.231,0.175299,0.000273498,0.938564 beta-lactamase_G194R,beta-lactamase_194,TEM-1,beta-lactamase,P62593,0.93858,NO,194,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.396,-3.912,2.516,5.46622,0.276,S,b,0.77,0.36,3.593,,67.83,POA,-1.832,0.221079,0.00392163,0.93858 beta-lactamase_625_I171M,beta-lactamase_625_171,TEM-1,beta-lactamase_625,P62593,0.938602,NO,171,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-2.431,-4.454,2.023,,0.361,,B,0.48,0.53,3.869,,77.62,HHO,-1.55533,0.213352,0.00623355,0.938602 gb1_T281A,gb1_281,gb1,gb1,P06654,0.938651,NO,281,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.828,-1.957,0.129,,,,,,,1.038,,35.71,HPA,-1.63667,0.177985,0.00284418,0.938651 beta-lactamase_0_L197T,beta-lactamase_0_197,TEM-1,beta-lactamase_0,P62593,0.938706,NO,197,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.853,-3.419,2.566,,0.007,S,B,0.55,0.33,1.087,,60.14,HHP,-1.833,0.0500837,0.00144602,0.938706 beta-lactamase_39_K213W,beta-lactamase_39_213,TEM-1,beta-lactamase_39,P62593,0.938711,NO,213,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.81,-5.386,3.576,,0.67,,A,2.34,0.29,2.648,,67.83,ABH,-1.57767,0.0495842,0.00610411,0.938711 beta-lactamase_39_D271K,beta-lactamase_39_271,TEM-1,beta-lactamase_39,P62593,0.938734,NO,271,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.0495842,0.00752082,0.938734 beta-lactamase_A77D,beta-lactamase_77,TEM-1,beta-lactamase,P62593,0.938755,NO,77,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.234,-3.775,2.541,4.75777,0.039,H,A,0.52,-0.56,1.708,,64.34,OHH,-1.294,0.221079,0.00282362,0.938755 beta-lactamase_T261A,beta-lactamase_261,TEM-1,beta-lactamase,P62593,0.938755,NO,261,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.88,-2.684,-0.196,5.65483,0.014,E,B,0.53,-0.39,2.449,,77.62,HPP,-1.771,0.221079,0.0123091,0.938755 beta-lactamase_0_T264I,beta-lactamase_0_264,TEM-1,beta-lactamase_0,P62593,0.938766,NO,264,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.0500837,0.0119399,0.938766 Pab1_G193E,Pab1_193,Pab1,Pab1,P04147,0.938769,NO,193,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.414,-3.123,1.709,,,,,,,,,,POP,-1.55733,0.175299,0.0014922,0.938769 beta-lactamase_0_G216T,beta-lactamase_0_216,TEM-1,beta-lactamase_0,P62593,0.938777,NO,216,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.477,-3.599,2.122,,0.437,I,A,0.29,-0.58,0.834,,74.48,HOO,-1.68067,0.0500837,0.00639568,0.938777 beta-lactamase_V82T,beta-lactamase_82,TEM-1,beta-lactamase,P62593,0.938785,NO,82,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.325,-3.392,2.067,5.27777,0.267,H,A,0.96,0.08,1.379,,93.01,BHA,-1.28567,0.221079,0.00397046,0.938785 beta-lactamase_0_D33K,beta-lactamase_0_33,TEM-1,beta-lactamase_0,P62593,0.938791,NO,33,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.321,-3.459,1.138,,0.366,H,A,0.75,0.33,12.514,12.514,77.62,BAH,-2.12133,0.0500837,0.00435556,0.938791 beta-lactamase_0_I245Y,beta-lactamase_0_245,TEM-1,beta-lactamase_0,P62593,0.93881,NO,245,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.0500837,0.00391032,0.93881 kka2_1:1_D238K,kka2_1:1_238,Kka2,kka2_1:1,P00552,0.938812,NO,238,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.83,-2.641,-0.189,,0.604,H,A,0.75,-0.33,11.329,11.329,92.05,HAB,-2.633,0.520039,0.0113863,0.938812 beta-lactamase_39_M153Y,beta-lactamase_39_153,TEM-1,beta-lactamase_39,P62593,0.938822,NO,153,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-3.193,-4.187,0.994,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.0495842,0.00509109,0.938822 Pab1_P135G,Pab1_135,Pab1,Pab1,P04147,0.938823,NO,135,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.457,-3.128,1.671,,,,,,,6.41,,81.8,BOA,-1.53367,0.175299,0.00148028,0.938823 beta-lactamase_2500_A222P,beta-lactamase_2500_222,TEM-1,beta-lactamase_2500,P62593,0.938828,NO,222,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.103,-2.971,0.868,,0.233,H,A,0.46,-0.25,0.379,,77.62,PHH,-1.63733,0.361275,0.00466094,0.938828 kka2_1:8_T130W,kka2_1:8_130,Kka2,kka2_1:8,P00552,0.938853,NO,130,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.392,-5.541,3.149,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.100394,0.00804204,0.938853 kka2_1:8_T130W,kka2_1:8_130,Kka2,kka2_1:8,P00552,0.938853,NO,130,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.392,-5.541,3.149,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.100394,0.00804204,0.938853 PSD95pdz3_Y392M,PSD95pdz3_392,PSD95pdz3,PSD95pdz3,P31016,0.938861,NO,392,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-1.437,-4.162,2.725,5.20337,,,,,11.725,,,,PHB,-1.51733,0.0758425,0.000935211,0.938861 beta-lactamase_N152I,beta-lactamase_152,TEM-1,beta-lactamase,P62593,0.938891,NO,152,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-2.757,-3.192,0.435,5.98571,0.863,H,A,0.09,0.92,2.061,,77.62,BPH,-2.97,0.221079,0.00471429,0.938891 PSD95pdz3_I338G,PSD95pdz3_338,PSD95pdz3,PSD95pdz3,P31016,0.938914,NO,338,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.63,-3.49,1.86,5.45113,,,,,13.0087,,,,HHP,-1.55767,0.0758425,0.000862587,0.938914 beta-lactamase_39_M180Q,beta-lactamase_39_180,TEM-1,beta-lactamase_39,P62593,0.938926,NO,180,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-2.795,-3.924,1.129,,0.242,,B,0.55,-0.94,3.579,,77.62,PHO,-1.56433,0.0495842,0.00552048,0.938926 kka2_1:8_S105I,kka2_1:8_105,Kka2,kka2_1:8,P00552,0.938932,NO,105,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.945,-3.89,1.945,,0.056,S,B,0.27,-1.04,2.115,,65.53,PPB,-2.17033,0.100394,0.00847233,0.938932 kka2_1:8_S105I,kka2_1:8_105,Kka2,kka2_1:8,P00552,0.938932,NO,105,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.945,-3.89,1.945,,0.056,S,B,0.27,-1.04,2.115,,65.53,PPB,-2.17033,0.100394,0.00847233,0.938932 beta-lactamase_A9V,beta-lactamase_9,TEM-1,beta-lactamase,P62593,0.938933,NO,9,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.147,-2.598,0.451,,,,,,,5.128,,72.73,HHH,-2.04267,0.221079,0.00247263,0.938933 beta-lactamase_625_S266K,beta-lactamase_625_266,TEM-1,beta-lactamase_625,P62593,0.938955,NO,266,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.213352,0.0140785,0.938955 beta-lactamase_2500_T138F,beta-lactamase_2500_138,TEM-1,beta-lactamase_2500,P62593,0.938959,NO,138,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.506,-4.444,1.938,,0.662,H,A,0.22,-0.03,30.445,30.445,73.78,HPP,-1.81233,0.361275,0.00487868,0.938959 beta-lactamase_K30Q,beta-lactamase_30,TEM-1,beta-lactamase,P62593,0.938966,NO,30,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-2.307,-2.158,-0.149,5.30605,0.142,H,A,1.82,-0.65,2.434,,93.01,HBH,-2.32833,0.221079,0.00448593,0.938966 beta-lactamase_L111F,beta-lactamase_111,TEM-1,beta-lactamase,P62593,0.938966,NO,111,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.76,-2.976,1.216,5.8705,0.328,T,A,0.84,0.93,3.836,,64.34,BHP,-1.884,0.221079,0.00480671,0.938966 beta-lactamase_0_A133K,beta-lactamase_0_133,TEM-1,beta-lactamase_0,P62593,0.938986,NO,133,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.186,-3.614,2.428,,,H,A,0.46,-0.86,2.148,,67.83,HHP,-0.988333,0.0500837,0.00468022,0.938986 beta-lactamase_39_P172I,beta-lactamase_39_172,TEM-1,beta-lactamase_39,P62593,0.93899,NO,172,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.998,-3.854,2.856,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.0495842,0.00312594,0.93899 E1_Ubiquitin_H70M,E1_Ubiquitin_70,Uba1,E1_Ubiquitin,P0CG63,0.938992,NO,70,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-1.36,,,,0.05,E,B,0.61,-0.97,,,93.18,HBH,-1.146,0.18783,0.00206914,0.938992 E1_Ubiquitin_L73E,E1_Ubiquitin_73,Uba1,E1_Ubiquitin,P0CG63,0.938992,NO,73,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.039,-3.707,2.668,,0.518,,B,1.3,1,,,,BHB,-1.175,0.18783,0.00111236,0.938992 E1_Ubiquitin_T68K,E1_Ubiquitin_68,Uba1,E1_Ubiquitin,P0CG63,0.938992,NO,68,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,,,,,,,,,,,,,OPH,-1.039,0.18783,0.00314321,0.938992 beta-lactamase_E145L,beta-lactamase_145,TEM-1,beta-lactamase,P62593,0.939013,NO,145,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.357,-3.644,1.287,5.38104,0.545,H,A,0.52,0.79,2.124,,77.62,BAH,-2.069,0.221079,0.00553285,0.939013 beta-lactamase_0_E145L,beta-lactamase_0_145,TEM-1,beta-lactamase_0,P62593,0.939036,NO,145,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.357,-3.644,1.287,,0.545,H,A,1.04,0.79,1.199,,77.62,BAH,-2.069,0.0500837,0.00553285,0.939036 beta-lactamase_0_E279F,beta-lactamase_0_279,TEM-1,beta-lactamase_0,P62593,0.939055,NO,279,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.0500837,0.0192826,0.939055 Pab1_D136T,Pab1_136,Pab1,Pab1,P04147,0.939055,NO,136,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.602,-3.23,1.628,,,,,,,,,,OAH,-1.42367,0.175299,0.00227029,0.939055 beta-lactamase_0_N152P,beta-lactamase_0_152,TEM-1,beta-lactamase_0,P62593,0.939064,NO,152,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-2.757,-3.97,1.213,,0.863,H,A,0.61,0.92,2.151,,77.62,BPH,-2.97,0.0500837,0.00471429,0.939064 beta-lactamase_2500_M67V,beta-lactamase_2500_67,TEM-1,beta-lactamase_2500,P62593,0.939091,NO,67,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-2.231,-2.772,0.541,,0.006,G,P,0.55,-0.81,2.653,,65.03,HHP,-1.502,0.361275,0.00409753,0.939091 beta-lactamase_2500_K190W,beta-lactamase_2500_190,TEM-1,beta-lactamase_2500,P62593,0.939186,NO,190,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.994,-5.522,3.528,,0.371,H,A,2.34,0.16,29.753,29.753,77.62,BBH,-1.64167,0.361275,0.00574527,0.939186 WW_domain_K181E,WW_domain_181,Yap65,WW_domain,P46937,0.939186,NO,181,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.35,-3.016,1.666,5.0864,,,,,,0.176,,15.87,HBP,-1.247,0.153962,0.0033022,0.939186 beta-lactamase_0_G43H,beta-lactamase_0_43,TEM-1,beta-lactamase_0,P62593,0.939232,NO,43,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.62,-4.68,4.06,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.0500837,0.00120151,0.939232 beta-lactamase_39_G142D,beta-lactamase_39_142,TEM-1,beta-lactamase_39,P62593,0.939234,NO,142,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.707,-3.466,2.759,,0.034,,p,0.29,-0.64,1.947,,64.69,OOO,-0.834,0.0495842,0.00060149,0.939234 beta-lactamase_0_L191W,beta-lactamase_0_191,TEM-1,beta-lactamase_0,P62593,0.939252,NO,191,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.087,-5.14,4.053,,,H,A,0.55,0.09,12.255,12.255,63.29,BHH,-1.445,0.0500837,0.00263549,0.939252 beta-lactamase_2500_K30M,beta-lactamase_2500_30,TEM-1,beta-lactamase_2500,P62593,0.939272,NO,30,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-2.307,-4.578,2.271,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.361275,0.00448593,0.939272 kka2_1:4_R145A,kka2_1:4_145,Kka2,kka2_1:4,P00552,0.939283,NO,145,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.804,-2.368,0.564,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.168804,0.00846663,0.939283 kka2_1:4_W24L,kka2_1:4_24,Kka2,kka2_1:4,P00552,0.93929,NO,24,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-1.779,-2.533,0.754,,0.477,E,B,1.51,-0.21,2.666,,56.06,AHH,-2.24467,0.168804,0.00631564,0.93929 beta-lactamase_2500_A222G,beta-lactamase_2500_222,TEM-1,beta-lactamase_2500,P62593,0.939292,NO,222,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.103,-1.732,-0.371,,0.233,H,A,0.46,-0.25,0.379,,77.62,PHH,-1.63733,0.361275,0.00466094,0.939292 beta-lactamase_625_G114A,beta-lactamase_625_114,TEM-1,beta-lactamase_625,P62593,0.939312,NO,114,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.094,-2.444,1.35,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.213352,0.00224919,0.939312 PSD95pdz3_R318G,PSD95pdz3_318,PSD95pdz3,PSD95pdz3,P31016,0.939325,NO,318,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.582,-3.04,1.458,4.94876,,,,,17.5609,,,,BBO,-1.40567,0.0758425,0.00110471,0.939325 beta-lactamase_0_G243H,beta-lactamase_0_243,TEM-1,beta-lactamase_0,P62593,0.939378,NO,243,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.0500837,0.00464034,0.939378 kka2_1:4_L103C,kka2_1:4_103,Kka2,kka2_1:4,P00552,0.939473,NO,103,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-2.362,-4.794,2.432,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.168804,0.00574792,0.939473 beta-lactamase_0_N130V,beta-lactamase_0_130,TEM-1,beta-lactamase_0,P62593,0.939483,NO,130,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-0.798,-3.754,2.956,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.0500837,0.000683376,0.939483 kka2_1:8_S54R,kka2_1:8_54,Kka2,kka2_1:8,P00552,0.939486,NO,54,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.471,-2.798,0.327,,0.408,S,b,0.77,1.01,13.679,13.679,71.59,HPO,-2.259,0.100394,0.00782867,0.939486 kka2_1:8_S54R,kka2_1:8_54,Kka2,kka2_1:8,P00552,0.939486,NO,54,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.471,-2.798,0.327,,0.408,S,b,0.77,1.01,13.679,13.679,71.59,HPO,-2.259,0.100394,0.00782867,0.939486 beta-lactamase_2500_W163F,beta-lactamase_2500_163,TEM-1,beta-lactamase_2500,P62593,0.9395,NO,163,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-1.843,-3.138,1.295,,0.467,,B,0.47,-0.5,32.624,32.624,63.99,BHA,-1.269,0.361275,0.00418955,0.9395 beta-lactamase_39_D48T,beta-lactamase_39_48,TEM-1,beta-lactamase_39,P62593,0.939526,NO,48,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.101,-3.511,2.41,,0.189,E,B,0.75,0.21,0.735,,50.35,HAH,-1.62467,0.0495842,0.0027273,0.939526 beta-lactamase_0_S241T,beta-lactamase_0_241,TEM-1,beta-lactamase_0,P62593,0.93954,NO,241,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.0500837,0.00452736,0.93954 beta-lactamase_Y103F,beta-lactamase_103,TEM-1,beta-lactamase,P62593,0.939552,NO,103,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-1.33,-3.391,2.061,5.71734,0.613,S,l,2.55,1.21,5.721,,63.29,AHP,-1.48767,0.221079,0.00443048,0.939552 kka2_1:2_N195D,kka2_1:2_195,Kka2,kka2_1:2,P00552,0.939557,NO,195,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-0.836,-2.379,1.543,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.295029,0.00276134,0.939557 beta-lactamase_39_M180W,beta-lactamase_39_180,TEM-1,beta-lactamase_39,P62593,0.939558,NO,180,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-2.795,-5.124,2.329,,0.242,,B,0.55,-0.94,3.579,,77.62,PHO,-1.56433,0.0495842,0.00552048,0.939558 Pab1_L190W,Pab1_190,Pab1,Pab1,P04147,0.939563,NO,190,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.325,-4.998,3.673,,0.489,E,B,,2.59,,,,HHH,-1.31033,0.175299,0.00132347,0.939563 kka2_1:2_D82N,kka2_1:2_82,Kka2,kka2_1:2,P00552,0.939565,NO,82,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.946,-3.098,1.152,,0.341,E,b,0.75,0.52,11.923,11.923,63.64,HAH,-1.98,0.295029,0.00637516,0.939565 kka2_1:8_G245E,kka2_1:8_245,Kka2,kka2_1:8,P00552,0.939565,NO,245,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.812,-2.733,1.921,,0.655,T,g,0.75,0.03,1.148,,65.53,HOH,-1.19833,0.100394,0.00683899,0.939565 kka2_1:8_G245E,kka2_1:8_245,Kka2,kka2_1:8,P00552,0.939565,NO,245,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.812,-2.733,1.921,,0.655,T,g,0.75,0.03,1.148,,65.53,HOH,-1.19833,0.100394,0.00683899,0.939565 PSD95pdz3_N326F,PSD95pdz3_326,PSD95pdz3,PSD95pdz3,P31016,0.939566,NO,326,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-1.41,-3.974,2.564,5.52537,,,,,19.0688,,,,HPH,-1.52133,0.0758425,0.00101078,0.939566 kka2_1:4_P128R,kka2_1:4_128,Kka2,kka2_1:4,P00552,0.939585,NO,128,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.922,-4.235,2.313,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.168804,0.00774689,0.939585 gb1_E268P,gb1_268,gb1,gb1,P06654,0.939591,NO,268,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.918,-3.659,1.741,,,,,,,0.637,,37.28,OAH,-1.59733,0.177985,0.00423953,0.939591 beta-lactamase_2500_A183K,beta-lactamase_2500_183,TEM-1,beta-lactamase_2500,P62593,0.939597,NO,183,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.231,-3.508,2.277,,0.155,H,A,0.46,-0.91,12.189,,77.62,HHH,-1.53367,0.361275,0.00296631,0.939597 WW_domain_K181Q,WW_domain_181,Yap65,WW_domain,P46937,0.939661,NO,181,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.35,-3.475,2.125,5.0864,,,,,,0.176,,15.87,HBP,-1.247,0.153962,0.0033022,0.939661 kka2_1:4_S114I,kka2_1:4_114,Kka2,kka2_1:4,P00552,0.939662,NO,114,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.527,-3.933,1.406,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.168804,0.00705262,0.939662 beta-lactamase_R189E,beta-lactamase_189,TEM-1,beta-lactamase,P62593,0.939719,NO,189,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.844,-2.256,0.412,5.74877,0.278,H,A,0.68,1.01,1.512,,72.73,HBB,-1.668,0.221079,0.0050699,0.939719 beta-lactamase_39_H287I,beta-lactamase_39_287,TEM-1,beta-lactamase_39,P62593,0.939731,NO,287,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,,,,,,,,,,,,,BBH,-1.111,0.0495842,,0.939731 beta-lactamase_2500_L160A,beta-lactamase_2500_160,TEM-1,beta-lactamase_2500,P62593,0.939741,NO,160,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.977,-3.094,2.117,,0.022,,B,0.55,-0.6,0.895,,44.41,BHA,-0.936,0.361275,0.00193775,0.939741 kka2_1:8_V214G,kka2_1:8_214,Kka2,kka2_1:8,P00552,0.939802,NO,214,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.261,-3.813,2.552,,0.117,E,B,1.48,-0.31,1.859,,64.39,OHH,-0.941667,0.100394,0.00692782,0.939802 kka2_1:8_V214G,kka2_1:8_214,Kka2,kka2_1:8,P00552,0.939802,NO,214,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.261,-3.813,2.552,,0.117,E,B,1.48,-0.31,1.859,,64.39,OHH,-0.941667,0.100394,0.00692782,0.939802 beta-lactamase_0_T147L,beta-lactamase_0_147,TEM-1,beta-lactamase_0,P62593,0.939816,NO,147,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.149,-3.242,2.093,,0.281,H,A,0.22,-0.68,3.487,,64.34,HPH,-1.456,0.0500837,0.00226017,0.939816 gb1_I232D,gb1_232,gb1,gb1,P06654,0.939825,NO,232,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-2.175,-3.582,1.407,,,,,,,0.766,,44.87,HHH,-2.152,0.177985,0.00580459,0.939825 gb1_T270D,gb1_270,gb1,gb1,P06654,0.939825,NO,270,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-3.15,-3.39,0.24,,,,,,,1.326,,45.54,HPH,-1.843,0.177985,0.00223707,0.939825 beta-lactamase_0_D177N,beta-lactamase_0_177,TEM-1,beta-lactamase_0,P62593,0.93995,NO,177,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.967,-2.571,1.604,,0.006,T,L,0.75,-1.02,3.536,,64.69,BAP,-0.873667,0.0500837,0.000864022,0.93995 beta-lactamase_39_D36I,beta-lactamase_39_36,TEM-1,beta-lactamase_39,P62593,0.93996,NO,36,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.732,-4.112,1.38,,0.555,H,A,0.75,1.17,13.689,13.689,77.62,AAP,-1.91167,0.0495842,0.00476483,0.93996 beta-lactamase_0_L55T,beta-lactamase_0_55,TEM-1,beta-lactamase_0,P62593,0.939962,NO,55,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.86,-3.617,1.757,,0.372,E,A,0.55,-0.36,1.967,,63.99,HHA,-2.247,0.0500837,0.00403741,0.939962 beta-lactamase_V72I,beta-lactamase_72,TEM-1,beta-lactamase,P62593,0.939977,NO,72,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.658,-3.311,1.653,5.80324,,H,A,2.78,-1.03,2.964,,65.73,BHH,-1.32167,0.221079,0.00501194,0.939977 beta-lactamase_0_L199F,beta-lactamase_0_199,TEM-1,beta-lactamase_0,P62593,0.940055,NO,199,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-2.942,-4.403,1.461,,0.832,H,A,0.55,0.42,10.85,10.85,77.62,PHH,-2.32933,0.0500837,0.0048649,0.940055 beta-lactamase_0_M209D,beta-lactamase_0_209,TEM-1,beta-lactamase_0,P62593,0.940056,NO,209,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.442,-4.067,2.625,,,H,A,0.55,-0.97,3.876,,64.69,HHA,-1.52633,0.0500837,0.00625021,0.940056 Pab1_G167Y,Pab1_167,Pab1,Pab1,P04147,0.94007,NO,167,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.223,-4.212,2.989,,0.195,S,g,,0.03,,,,BOH,-1.25133,0.175299,0.00146449,0.94007 beta-lactamase_156_L223H,beta-lactamase_156_223,TEM-1,beta-lactamase_156,P62593,0.940136,NO,223,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.055,-4.894,3.839,,0.27,,B,0.55,0.09,1.511,,74.48,HHO,-1.35033,0.111618,0.00372793,0.940136 kka2_1:4_V80Y,kka2_1:4_80,Kka2,kka2_1:4,P00552,0.940142,NO,80,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.144,-4.109,2.965,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.168804,0.00488211,0.940142 beta-lactamase_2500_L28A,beta-lactamase_2500_28,TEM-1,beta-lactamase_2500,P62593,0.94015,NO,28,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.579,-2.126,0.547,,0.277,H,A,0.55,-0.16,2.716,,93.01,PHH,-2.11333,0.361275,0.00359321,0.94015 Pab1_S155A,Pab1_155,Pab1,Pab1,P04147,0.940198,NO,155,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.039,-2.719,0.68,,,,,,,,,,PPB,-1.42267,0.175299,0.00208179,0.940198 kka2_1:2_G88D,kka2_1:2_88,Kka2,kka2_1:2,P00552,0.940216,NO,88,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.689,-2.184,0.495,,0.54,S,l,0.75,1.51,2.814,,65.53,HOB,-1.718,0.295029,0.00685559,0.940216 kka2_1:4_V97M,kka2_1:4_97,Kka2,kka2_1:4,P00552,0.940221,NO,97,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.453,-2.867,1.414,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.168804,0.00737869,0.940221 beta-lactamase_39_D36Y,beta-lactamase_39_36,TEM-1,beta-lactamase_39,P62593,0.94026,NO,36,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.732,-3.266,0.534,,0.555,H,A,0.75,1.17,13.689,13.689,77.62,AAP,-1.91167,0.0495842,0.00476483,0.94026 WW_domain_R187W,WW_domain_187,Yap65,WW_domain,P46937,0.940286,NO,187,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.402,-5.162,3.76,5.05189,,,,,,3.431,,78.57,PBH,-1.362,0.153962,0.00171149,0.940286 PSD95pdz3_L342G,PSD95pdz3_342,PSD95pdz3,PSD95pdz3,P31016,0.94035,NO,342,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.347,-3.49,2.143,5.03015,,,,,12.0762,,,,HHH,-1.428,0.0758425,0.00081112,0.94035 beta-lactamase_2500_V42I,beta-lactamase_2500_42,TEM-1,beta-lactamase_2500,P62593,0.94037,NO,42,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.564,-2.098,0.534,,0.017,E,B,0.44,-0.51,1.86,,63.99,BHO,-1.042,0.361275,0.00404515,0.94037 beta-lactamase_625_T27C,beta-lactamase_625_27,TEM-1,beta-lactamase_625,P62593,0.940381,NO,27,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.905,-4.927,3.022,,0.007,H,A,0.22,-0.37,3.72,,93.01,APH,-1.97933,0.213352,0.00306559,0.940381 beta-lactamase_0_P60H,beta-lactamase_0_60,TEM-1,beta-lactamase_0,P62593,0.940387,NO,60,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-2.469,-3.266,0.797,,0.256,T,A,0.52,-0.56,3.653,,77.62,BOA,-1.97633,0.0500837,0.00521318,0.940387 beta-lactamase_0_L167K,beta-lactamase_0_167,TEM-1,beta-lactamase_0,P62593,0.940406,NO,167,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.138,-3.594,2.456,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.0500837,0.00303566,0.940406 beta-lactamase_2500_F228W,beta-lactamase_2500_228,TEM-1,beta-lactamase_2500,P62593,0.940407,NO,228,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-2.342,-5.275,2.933,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.361275,0.0046669,0.940407 kka2_1:4_Y244T,kka2_1:4_244,Kka2,kka2_1:4,P00552,0.94042,NO,244,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-0.775,-3.675,2.9,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.168804,0.00453187,0.94042 beta-lactamase_0_T178E,beta-lactamase_0_178,TEM-1,beta-lactamase_0,P62593,0.940437,NO,178,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-0.791,-3.44,2.649,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.0500837,0.000684366,0.940437 beta-lactamase_0_G43I,beta-lactamase_0_43,TEM-1,beta-lactamase_0,P62593,0.94046,NO,43,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.62,-4.235,3.615,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.0500837,0.00120151,0.94046 beta-lactamase_625_G141L,beta-lactamase_625_141,TEM-1,beta-lactamase_625,P62593,0.940465,NO,141,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.828,-3.844,3.016,,0.575,T,l,0.29,-0.28,0.198,,64.69,HOO,-1.08933,0.213352,0.0012419,0.940465 beta-lactamase_2500_P60L,beta-lactamase_2500_60,TEM-1,beta-lactamase_2500,P62593,0.940474,NO,60,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-2.469,-2.818,0.349,,0.256,T,A,0.52,-0.56,1.581,,77.62,BOA,-1.97633,0.361275,0.00521318,0.940474 beta-lactamase_2500_M153F,beta-lactamase_2500_153,TEM-1,beta-lactamase_2500,P62593,0.940484,NO,153,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-3.193,-3.944,0.751,,0.14,T,A,0.55,-0.11,3.409,,77.62,PHO,-2.25767,0.361275,0.00509109,0.940484 Pab1_D151I,Pab1_151,Pab1,Pab1,P04147,0.940499,NO,151,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.399,-3.964,1.565,,,,,,,,,,OAH,-1.51767,0.175299,0.00228155,0.940499 beta-lactamase_0_L191N,beta-lactamase_0_191,TEM-1,beta-lactamase_0,P62593,0.940503,NO,191,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.087,-4.164,3.077,,,H,A,0.55,0.09,12.255,12.255,63.29,BHH,-1.445,0.0500837,0.00263549,0.940503 beta-lactamase_39_A123N,beta-lactamase_39_123,TEM-1,beta-lactamase_39,P62593,0.940506,NO,123,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.834,-3.947,3.113,,0.039,H,A,0.46,-0.72,0.705,,41.26,PHH,-1.47367,0.0495842,0.0010157,0.940506 kka2_1:2_R173I,kka2_1:2_173,Kka2,kka2_1:2,P00552,0.940538,NO,173,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.407,-4.054,1.647,,0.308,H,A,0.16,-0.13,15.389,15.389,65.53,HBH,-1.70533,0.295029,0.00784999,0.940538 beta-lactamase_0_R91K,beta-lactamase_0_91,TEM-1,beta-lactamase_0,P62593,0.940614,NO,91,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.392,-2.505,1.113,,0.444,,B,1.2,0.96,4.557,,50.35,OBB,-1.73367,0.0500837,0.00380226,0.940614 beta-lactamase_2500_G265N,beta-lactamase_2500_265,TEM-1,beta-lactamase_2500,P62593,0.940614,NO,265,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.361275,0.00811926,0.940614 beta-lactamase_39_K213G,beta-lactamase_39_213,TEM-1,beta-lactamase_39,P62593,0.940615,NO,213,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.81,-2.317,0.507,,0.67,,A,2.34,0.29,2.648,,67.83,ABH,-1.57767,0.0495842,0.00610411,0.940615 beta-lactamase_39_M180A,beta-lactamase_39_180,TEM-1,beta-lactamase_39,P62593,0.940624,NO,180,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-2.795,-2.974,0.179,,0.242,,B,0.55,-0.94,3.579,,77.62,PHO,-1.56433,0.0495842,0.00552048,0.940624 kka2_1:8_E231D,kka2_1:8_231,Kka2,kka2_1:8,P00552,0.940669,NO,231,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.002,-2.09,0.088,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.100394,0.00732383,0.940669 kka2_1:8_E231D,kka2_1:8_231,Kka2,kka2_1:8,P00552,0.940669,NO,231,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.002,-2.09,0.088,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.100394,0.00732383,0.940669 beta-lactamase_0_A34P,beta-lactamase_0_34,TEM-1,beta-lactamase_0,P62593,0.940676,NO,34,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.059,-4.024,1.965,,,H,A,0.46,-0.54,3.998,,73.78,AHA,-1.74967,0.0500837,0.00407913,0.940676 beta-lactamase_2500_M127Y,beta-lactamase_2500_127,TEM-1,beta-lactamase_2500,P62593,0.940682,NO,127,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-2.251,-2.954,0.703,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.361275,0.00437927,0.940682 beta-lactamase_0_L146E,beta-lactamase_0_146,TEM-1,beta-lactamase_0,P62593,0.940701,NO,146,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.462,-3.93,2.468,,0.007,H,A,0.55,-0.56,2.051,,64.69,AHP,-1.656,0.0500837,0.00474542,0.940701 kka2_1:2_P249I,kka2_1:2_249,Kka2,kka2_1:2,P00552,0.94073,NO,249,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.867,-2.381,0.514,,0.406,.,B,0.52,-0.01,0.76,,92.05,HOA,-1.66867,0.295029,0.011045,0.94073 beta-lactamase_2500_S57H,beta-lactamase_2500_57,TEM-1,beta-lactamase_2500,P62593,0.940743,NO,57,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.918,-3.329,1.411,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.361275,0.00492804,0.940743 gb1_K230N,gb1_230,gb1,gb1,P06654,0.940757,NO,230,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.701,-3.459,1.758,,,,,,,0.166,,11.83,HBH,-1.52867,0.177985,0.00331703,0.940757 E1_Ubiquitin_A46V,E1_Ubiquitin_46,Uba1,E1_Ubiquitin,P0CG63,0.94076,NO,46,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.367,-3.131,1.764,,0.398,T,L,,-0.8,,,,HHO,-1.17167,0.18783,0.004233,0.94076 E1_Ubiquitin_Q41M,E1_Ubiquitin_41,Uba1,E1_Ubiquitin,P0CG63,0.94076,NO,41,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-1.25,-4.072,2.822,,0.017,E,B,,-0.98,,,,PPB,-1.344,0.18783,0.00215097,0.94076 kka2_1:1_S11R,kka2_1:1_11,Kka2,kka2_1:1,P00552,0.94076,NO,11,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.322,-3.926,1.604,,0.408,,B,0.77,1.64,2.054,,92.05,OPO,-1.69867,0.520039,0.00381691,0.94076 beta-lactamase_0_T269W,beta-lactamase_0_269,TEM-1,beta-lactamase_0,P62593,0.940765,NO,269,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.0500837,0.00950944,0.940765 beta-lactamase_R41T,beta-lactamase_41,TEM-1,beta-lactamase,P62593,0.940843,NO,41,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-0.942,-3.385,2.443,5.69185,0.321,E,B,0.91,-0.07,4.357,,65.03,HBH,-1.30267,0.221079,0.00123327,0.940843 kka2_1:4_E111N,kka2_1:4_111,Kka2,kka2_1:4,P00552,0.940843,NO,111,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.28,-3.19,0.91,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.168804,0.00746789,0.940843 beta-lactamase_156_L120S,beta-lactamase_156_120,TEM-1,beta-lactamase_156,P62593,0.940847,NO,120,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.044,-3.66,2.616,,,H,A,0.55,-1.13,7.813,,64.69,AHO,-1.13633,0.111618,0.00143563,0.940847 kka2_1:4_Q100L,kka2_1:4_100,Kka2,kka2_1:4,P00552,0.940857,NO,100,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.77,-2.853,0.083,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.168804,0.0066405,0.940857 beta-lactamase_2500_P25F,beta-lactamase_2500_25,TEM-1,beta-lactamase_2500,P62593,0.940867,NO,25,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.526,-4.406,2.88,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.361275,0.00347571,0.940867 beta-lactamase_39_K213D,beta-lactamase_39_213,TEM-1,beta-lactamase_39,P62593,0.940867,NO,213,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.81,-3.577,1.767,,0.67,,A,2.34,0.29,2.648,,67.83,ABH,-1.57767,0.0495842,0.00610411,0.940867 beta-lactamase_V78I,beta-lactamase_78,TEM-1,beta-lactamase,P62593,0.940895,NO,78,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.459,-1.96,0.501,4.79197,,H,A,0.96,-0.47,1.132,,63.64,HHH,-1.17833,0.221079,0.00492501,0.940895 beta-lactamase_F58A,beta-lactamase_58,TEM-1,beta-lactamase,P62593,0.940922,NO,58,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-2.914,-3.389,0.475,5.55634,0.266,E,B,1.33,-0.07,2.467,,77.62,PHB,-2.059,0.221079,0.00523369,0.940922 kka2_1:8_E17P,kka2_1:8_17,Kka2,kka2_1:8,P00552,0.940925,NO,17,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.154,-2.799,0.645,,0.957,T,A,1.04,0.22,31.483,31.483,63.64,HAB,-2.432,0.100394,0.00688738,0.940925 kka2_1:8_E17P,kka2_1:8_17,Kka2,kka2_1:8,P00552,0.940925,NO,17,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.154,-2.799,0.645,,0.957,T,A,1.04,0.22,31.483,31.483,63.64,HAB,-2.432,0.100394,0.00688738,0.940925 beta-lactamase_2500_P172Y,beta-lactamase_2500_172,TEM-1,beta-lactamase_2500,P62593,0.940944,NO,172,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.998,-4.368,3.37,,0.639,T,b,0.52,0.24,4.99,,74.48,HOP,-2.03067,0.361275,0.00312594,0.940944 kka2_1:2_G21T,kka2_1:2_21,Kka2,kka2_1:2,P00552,0.940948,NO,21,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.368,-3.639,2.271,,0.586,T,l,0.29,-0.75,2.026,,71.59,HOH,-2.10167,0.295029,0.00709648,0.940948 kka2_1:2_A56I,kka2_1:2_56,Kka2,kka2_1:2,P00552,0.940955,NO,56,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.083,-3.881,1.798,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.295029,0.00717715,0.940955 beta-lactamase_39_A215W,beta-lactamase_39_215,TEM-1,beta-lactamase_39,P62593,0.940992,NO,215,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.503,-5.336,3.833,,,,a,0.46,-0.93,0.494,,74.48,HHO,-1.42633,0.0495842,0.00544007,0.940992 beta-lactamase_0_K213D,beta-lactamase_0_213,TEM-1,beta-lactamase_0,P62593,0.941051,NO,213,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.81,-3.577,1.767,,0.67,,A,2.34,0.29,3.015,,67.83,ABH,-1.57767,0.0500837,0.00610411,0.941051 PSD95pdz3_P346I,PSD95pdz3_346,PSD95pdz3,PSD95pdz3,P31016,0.941057,NO,346,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.236,-3.692,2.456,5.02406,,,,,14.6629,,,,OOH,-1.18367,0.0758425,0.000758563,0.941057 kka2_1:4_E160T,kka2_1:4_160,Kka2,kka2_1:4,P00552,0.941061,NO,160,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.683,-3.562,1.879,,0.989,G,A,1.04,2.28,2.531,,71.59,AAA,-1.36133,0.168804,0.00935762,0.941061 beta-lactamase_E145W,beta-lactamase_145,TEM-1,beta-lactamase,P62593,0.941062,NO,145,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.357,-5.352,2.995,5.38104,0.545,H,A,0.52,0.79,2.124,,77.62,BAH,-2.069,0.221079,0.00553285,0.941062 beta-lactamase_L47T,beta-lactamase_47,TEM-1,beta-lactamase,P62593,0.941062,NO,47,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.876,-2.727,0.851,5.27297,0.007,E,B,1.07,0.2,1.244,,67.83,AHA,-1.639,0.221079,0.00439844,0.941062 Pab1_G193T,Pab1_193,Pab1,Pab1,P04147,0.941074,NO,193,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.414,-3.388,1.974,,,,,,,,,,POP,-1.55733,0.175299,0.0014922,0.941074 kka2_1:8_L107A,kka2_1:8_107,Kka2,kka2_1:8,P00552,0.941082,NO,107,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.238,-3.204,1.966,,0.197,.,B,0.55,-1.1,4.478,,71.59,BHH,-2.143,0.100394,0.00561937,0.941082 kka2_1:8_L107A,kka2_1:8_107,Kka2,kka2_1:8,P00552,0.941082,NO,107,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.238,-3.204,1.966,,0.197,.,B,0.55,-1.1,4.478,,71.59,BHH,-2.143,0.100394,0.00561937,0.941082 WW_domain_A175H,WW_domain_175,Yap65,WW_domain,P46937,0.941104,NO,175,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.631,-4.54,2.909,6.69537,,,,,,6.257,,83.93,OHO,-1.30033,0.153962,0.00326874,0.941104 kka2_1:8_V153A,kka2_1:8_153,Kka2,kka2_1:8,P00552,0.941121,NO,153,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.092,-2.452,1.36,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.100394,0.00501119,0.941121 kka2_1:8_V153A,kka2_1:8_153,Kka2,kka2_1:8,P00552,0.941121,NO,153,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.092,-2.452,1.36,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.100394,0.00501119,0.941121 kka2_1:2_G151M,kka2_1:2_151,Kka2,kka2_1:2,P00552,0.941151,NO,151,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.873,-4.939,4.066,,0.678,T,l,0.29,1.36,1.357,,49.62,HOH,-1.11433,0.295029,0.00339918,0.941151 beta-lactamase_0_P165A,beta-lactamase_0_165,TEM-1,beta-lactamase_0,P62593,0.941154,NO,165,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.373,-3.022,1.649,,0.203,T,A,0.52,-0.31,3.242,,73.78,AOA,-1.359,0.0500837,0.00549538,0.941154 beta-lactamase_2500_I93M,beta-lactamase_2500_93,TEM-1,beta-lactamase_2500,P62593,0.941158,NO,93,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.401,-4.189,2.788,,0.128,E,B,0.48,0.44,19.374,19.374,67.83,BHB,-1.873,0.361275,0.00527066,0.941158 WW_domain_P174G,WW_domain_174,Yap65,WW_domain,P46937,0.941162,NO,174,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.035,-3.135,2.1,,,,,,,,,,HOH,-1.261,0.153962,0.000711366,0.941162 beta-lactamase_0_E164G,beta-lactamase_0_164,TEM-1,beta-lactamase_0,P62593,0.941205,NO,164,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-0.948,-2.443,1.495,,0.011,T,B,1.04,-0.4,1.011,,64.69,HAO,-1.388,0.0500837,0.00137286,0.941205 beta-lactamase_0_G281K,beta-lactamase_0_281,TEM-1,beta-lactamase_0,P62593,0.941213,NO,281,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.0500837,0.0406482,0.941213 beta-lactamase_R63T,beta-lactamase_63,TEM-1,beta-lactamase,P62593,0.941218,NO,63,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-0.943,-3.447,2.504,5.49979,0.218,,B,0.45,-0.31,0.677,,44.06,ABH,-0.992333,0.221079,0.00126938,0.941218 kka2_1:8_I207C,kka2_1:8_207,Kka2,kka2_1:8,P00552,0.941219,NO,207,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.175,-4.752,3.577,,0.293,,B,1.52,-1.12,1.306,,56.06,HHA,-1.07733,0.100394,0.00611824,0.941219 kka2_1:8_I207C,kka2_1:8_207,Kka2,kka2_1:8,P00552,0.941219,NO,207,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.175,-4.752,3.577,,0.293,,B,1.52,-1.12,1.306,,56.06,HHA,-1.07733,0.100394,0.00611824,0.941219 Pab1_H134K,Pab1_134,Pab1,Pab1,P04147,0.941223,NO,134,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-1.542,-3.344,1.802,,,,,,,,,,HBO,-1.346,0.175299,0.00116356,0.941223 kka2_1:4_D134E,kka2_1:4_134,Kka2,kka2_1:4,P00552,0.941227,NO,134,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.969,-2.461,1.492,,0.421,B,B,0.75,0.31,0.733,,49.62,HAB,-1.057,0.168804,0.00270812,0.941227 beta-lactamase_2500_G194P,beta-lactamase_2500_194,TEM-1,beta-lactamase_2500,P62593,0.941252,NO,194,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.396,-3.912,2.516,,0.276,S,b,0.29,0.36,3.593,,67.83,POA,-1.832,0.361275,0.00392163,0.941252 kka2_1:2_T85C,kka2_1:2_85,Kka2,kka2_1:2,P00552,0.941279,NO,85,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.165,-5.123,2.958,,0.576,E,B,0.22,1.39,1.853,,71.59,HPA,-2.10133,0.295029,0.00634493,0.941279 beta-lactamase_0_V78R,beta-lactamase_0_78,TEM-1,beta-lactamase_0,P62593,0.941283,NO,78,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.459,-4.181,2.722,,,H,A,0.44,-0.47,16.615,16.615,63.64,HHH,-1.17833,0.0500837,0.00492501,0.941283 hsp90_E590S,hsp90_590,hsp90,hsp90,P02829,0.941286,NO,590,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.818,-2.764,0,4.65049,0.021,H,A,,0.03,,,,HAO,-3.338,0.368192,0.000222939,0.941286 kka2_1:8_F206L,kka2_1:8_206,Kka2,kka2_1:8,P00552,0.941298,NO,206,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.349,-2.335,0.986,,0.006,E,B,1.62,-1.21,1.052,,63.64,OHH,-1.04,0.100394,0.00936868,0.941298 kka2_1:8_F206L,kka2_1:8_206,Kka2,kka2_1:8,P00552,0.941298,NO,206,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.349,-2.335,0.986,,0.006,E,B,1.62,-1.21,1.052,,63.64,OHH,-1.04,0.100394,0.00936868,0.941298 Pab1_Y197I,Pab1_197,Pab1,Pab1,P04147,0.9413,NO,197,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-1.345,-3.379,2.034,,,,,,,0.891,,80.42,HHH,-1.41767,0.175299,0.00302474,0.9413 beta-lactamase_2500_I45Y,beta-lactamase_2500_45,TEM-1,beta-lactamase_2500,P62593,0.941313,NO,45,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-2.421,-2.914,0.493,,,E,B,0.48,-0.3,3.793,,77.62,HHA,-2.30267,0.361275,0.00452842,0.941313 beta-lactamase_0_L205Y,beta-lactamase_0_205,TEM-1,beta-lactamase_0,P62593,0.941318,NO,205,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.922,-3.727,2.805,,,H,A,0.55,-0.46,1.065,,42.31,PHH,-1.57767,0.0500837,0.00255802,0.941318 beta-lactamase_2500_P255L,beta-lactamase_2500_255,TEM-1,beta-lactamase_2500,P62593,0.941333,NO,255,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.361275,0.00499612,0.941333 kka2_1:8_L152W,kka2_1:8_152,Kka2,kka2_1:8,P00552,0.941337,NO,152,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.521,-5.416,3.895,,0.547,.,A,0.55,1.36,1.442,,63.64,OHH,-1.162,0.100394,0.00674868,0.941337 kka2_1:8_L152W,kka2_1:8_152,Kka2,kka2_1:8,P00552,0.941337,NO,152,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.521,-5.416,3.895,,0.547,.,A,0.55,1.36,1.442,,63.64,OHH,-1.162,0.100394,0.00674868,0.941337 kka2_1:2_P45A,kka2_1:2_45,Kka2,kka2_1:2,P00552,0.941338,NO,45,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.774,-2.227,0.453,,0.669,,B,0.52,-0.76,4.882,,71.59,BOH,-2.152,0.295029,0.00590481,0.941338 beta-lactamase_0_A278R,beta-lactamase_0_278,TEM-1,beta-lactamase_0,P62593,0.941355,NO,278,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.348,,,,0.015,H,A,0.48,-0.85,4.624,,63.29,HHA,-1.41833,0.0500837,0.0310297,0.941355 beta-lactamase_156_D212L,beta-lactamase_156_212,TEM-1,beta-lactamase_156,P62593,0.941356,NO,212,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.624,-3.598,1.974,,0.037,,b,0.75,-0.58,20.222,20.222,74.48,HAB,-1.77667,0.111618,0.00644302,0.941356 beta-lactamase_39_T139V,beta-lactamase_39_139,TEM-1,beta-lactamase_39,P62593,0.941372,NO,139,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.901,-3.468,1.567,,0.216,H,A,0.22,0.39,0.421,,77.62,PPH,-2.04667,0.0495842,0.00441837,0.941372 beta-lactamase_G263D,beta-lactamase_263,TEM-1,beta-lactamase,P62593,0.941373,NO,263,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-2.031,-2.089,0.058,5.09799,0.517,S,l,0.77,0.31,16.425,16.425,77.62,POP,-1.78267,0.221079,0.0110582,0.941373 beta-lactamase_L111H,beta-lactamase_111,TEM-1,beta-lactamase,P62593,0.941373,NO,111,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.76,-4.922,3.162,5.8705,0.328,T,A,0.84,0.93,3.836,,64.34,BHP,-1.884,0.221079,0.00480671,0.941373 beta-lactamase_M184Y,beta-lactamase_184,TEM-1,beta-lactamase,P62593,0.941373,NO,184,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.593,-4.027,2.434,5.39575,,H,A,1.3,-0.87,2.893,,62.94,HHH,-1.41,0.221079,0.00356019,0.941373 beta-lactamase_T126M,beta-lactamase_126,TEM-1,beta-lactamase,P62593,0.941373,NO,126,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.122,-4.659,3.537,4.82694,0.05,H,A,0.3,-0.05,1.14,,44.41,HPH,-1.60467,0.221079,0.00244552,0.941373 beta-lactamase_0_A222C,beta-lactamase_0_222,TEM-1,beta-lactamase_0,P62593,0.941379,NO,222,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.103,-4.939,2.836,,0.233,H,A,0.46,-0.25,2.015,,77.62,PHH,-1.63733,0.0500837,0.00466094,0.941379 beta-lactamase_156_N134G,beta-lactamase_156_134,TEM-1,beta-lactamase_156,P62593,0.941391,NO,134,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-0.879,-2.976,2.097,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.111618,0.000644786,0.941391 PSD95pdz3_F340T,PSD95pdz3_340,PSD95pdz3,PSD95pdz3,P31016,0.941417,NO,340,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.524,-3.328,1.804,5.79283,,,,,11.8045,,,,PHH,-1.55767,0.0758425,0.000836987,0.941417 beta-lactamase_39_A225E,beta-lactamase_39_225,TEM-1,beta-lactamase_39,P62593,0.941457,NO,225,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.845,-2.246,0.401,,1,T,B,0.46,-0.38,9.874,9.874,74.48,OHO,-1.39967,0.0495842,0.00465057,0.941457 beta-lactamase_39_L160D,beta-lactamase_39_160,TEM-1,beta-lactamase_39,P62593,0.941507,NO,160,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.977,-4.122,3.145,,0.022,,B,0.55,-0.6,0.895,,44.41,BHA,-0.936,0.0495842,0.00193775,0.941507 beta-lactamase_0_A246P,beta-lactamase_0_246,TEM-1,beta-lactamase_0,P62593,0.94153,NO,246,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.121,-4.126,2.005,,0.01,E,B,0.46,-1.01,1.201,,73.78,HHH,-1.55633,0.0500837,0.00569458,0.94153 beta-lactamase_39_W227V,beta-lactamase_39_227,TEM-1,beta-lactamase_39,P62593,0.94154,NO,227,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-0.982,-3.747,2.765,,0.272,,B,0.47,-0.29,1.37,,74.48,OHH,-1.595,0.0495842,0.00226019,0.94154 beta-lactamase_156_D48H,beta-lactamase_156_48,TEM-1,beta-lactamase_156,P62593,0.941588,NO,48,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.101,-2.659,1.558,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.111618,0.0027273,0.941588 kka2_1:4_D180Y,kka2_1:4_180,Kka2,kka2_1:4,P00552,0.941588,NO,180,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.416,-3.544,1.128,,1.03,S,a,0.29,1.5,14.668,14.668,71.59,OAO,-2.02933,0.168804,0.00756412,0.941588 beta-lactamase_H94P,beta-lactamase_94,TEM-1,beta-lactamase,P62593,0.941605,NO,94,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-2.5,-2.499,-0.001,6.1507,0.776,,B,0.63,1.24,1.176,,77.62,HBH,-1.872,0.221079,0.00389226,0.941605 kka2_1:8_Q100G,kka2_1:8_100,Kka2,kka2_1:8,P00552,0.941632,NO,100,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.77,-3.044,0.274,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.100394,0.0066405,0.941632 kka2_1:8_Q100G,kka2_1:8_100,Kka2,kka2_1:8,P00552,0.941632,NO,100,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.77,-3.044,0.274,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.100394,0.0066405,0.941632 PSD95pdz3_R368D,PSD95pdz3_368,PSD95pdz3,PSD95pdz3,P31016,0.941654,NO,368,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.582,-3.375,1.793,6.13355,,,,,18.1818,,,,HBP,-1.50033,0.0758425,0.000451517,0.941654 gb1_T242Q,gb1_242,gb1,gb1,P06654,0.941685,NO,242,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.245,-3.635,2.39,,,,,,,,,,APP,-1.444,0.177985,0.00243886,0.941685 kka2_1:1_S11T,kka2_1:1_11,Kka2,kka2_1:1,P00552,0.941725,NO,11,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.322,-3.33,1.008,,0.408,,B,0.77,1.64,2.054,,92.05,OPO,-1.69867,0.520039,0.00381691,0.941725 beta-lactamase_156_M184S,beta-lactamase_156_184,TEM-1,beta-lactamase_156,P62593,0.941746,NO,184,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.593,-3.463,1.87,,,H,A,0.55,-0.87,1.671,,62.94,HHH,-1.41,0.111618,0.00356019,0.941746 Pab1_L190S,Pab1_190,Pab1,Pab1,P04147,0.941751,NO,190,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.325,-2.347,1.022,,0.489,E,B,,2.59,,,,HHH,-1.31033,0.175299,0.00132347,0.941751 beta-lactamase_2500_E145I,beta-lactamase_2500_145,TEM-1,beta-lactamase_2500,P62593,0.941759,NO,145,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.357,-4.11,1.753,,0.545,H,A,1.04,0.79,2.124,,77.62,BAH,-2.069,0.361275,0.00553285,0.941759 Pab1_F146G,Pab1_146,Pab1,Pab1,P04147,0.941786,NO,146,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.149,-3.4,2.251,,0.006,H,A,,0.75,,,,PHP,-1.161,0.175299,0.000329265,0.941786 kka2_1:8_S32G,kka2_1:8_32,Kka2,kka2_1:8,P00552,0.941789,NO,32,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-0.804,-2.936,2.132,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.100394,0.00149998,0.941789 kka2_1:8_S32G,kka2_1:8_32,Kka2,kka2_1:8,P00552,0.941789,NO,32,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-0.804,-2.936,2.132,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.100394,0.00149998,0.941789 beta-lactamase_A276N,beta-lactamase_276,TEM-1,beta-lactamase,P62593,0.941809,NO,276,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.144,-3.773,2.629,5.1387,0.117,H,A,0.52,-0.84,1.283,,44.06,HHA,-1.47,0.221079,0.0191712,0.941809 beta-lactamase_R92N,beta-lactamase_92,TEM-1,beta-lactamase,P62593,0.941809,NO,92,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.718,-2.988,1.27,5.65832,0.479,E,B,0.91,1.36,3.069,,65.38,BBH,-1.50367,0.221079,0.00429626,0.941809 beta-lactamase_0_G43R,beta-lactamase_0_43,TEM-1,beta-lactamase_0,P62593,0.941836,NO,43,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.62,-3.933,3.313,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.0500837,0.00120151,0.941836 beta-lactamase_156_A268Y,beta-lactamase_156_268,TEM-1,beta-lactamase_156,P62593,0.941844,NO,268,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.111618,0.0102525,0.941844 beta-lactamase_0_Y103H,beta-lactamase_0_103,TEM-1,beta-lactamase_0,P62593,0.94185,NO,103,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-1.33,-2.243,0.913,,0.613,S,l,0.21,1.21,1.646,,63.29,AHP,-1.48767,0.0500837,0.00443048,0.94185 beta-lactamase_A222Y,beta-lactamase_222,TEM-1,beta-lactamase,P62593,0.941863,NO,222,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.103,-4.186,2.083,5.2262,0.233,H,A,0.47,-0.25,0.379,,77.62,PHH,-1.63733,0.221079,0.00466094,0.941863 beta-lactamase_0_I206K,beta-lactamase_0_206,TEM-1,beta-lactamase_0,P62593,0.941899,NO,206,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-2.429,-3.632,1.203,,0.173,H,A,0.48,-0.34,3.411,,77.62,HHA,-1.805,0.0500837,0.00528934,0.941899 PSD95pdz3_L367H,PSD95pdz3_367,PSD95pdz3,PSD95pdz3,P31016,0.941911,NO,367,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.347,-4.587,3.24,5.47696,,,,,17.0063,,,,AHB,-1.39767,0.0758425,0.000466436,0.941911 kka2_1:8_Q136W,kka2_1:8_136,Kka2,kka2_1:8,P00552,0.941926,NO,136,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-3.021,-5.446,2.425,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.100394,0.00624149,0.941926 kka2_1:8_Q136W,kka2_1:8_136,Kka2,kka2_1:8,P00552,0.941926,NO,136,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-3.021,-5.446,2.425,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.100394,0.00624149,0.941926 beta-lactamase_H151D,beta-lactamase_151,TEM-1,beta-lactamase,P62593,0.941931,NO,151,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-2.96,-3.624,0.664,5.47408,0.594,H,A,0.35,0.1,1.843,,77.62,HBP,-2.34767,0.221079,0.00216946,0.941931 beta-lactamase_N272D,beta-lactamase_272,TEM-1,beta-lactamase,P62593,0.941931,NO,272,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-1.127,-2.041,0.914,5.37826,0.081,H,A,0.09,-0.97,1.468,,63.64,BPB,-1.56333,0.221079,0.00545371,0.941931 beta-lactamase_0_C75F,beta-lactamase_0_75,TEM-1,beta-lactamase_0,P62593,0.941932,NO,75,C,F,CF,Special,Hydrophobic,5.07,3.32051,-1.74949,205,121,165,44,108.5,189.9,81.4,-1.245,-4.17,2.925,,,H,A,0.46,-0.87,2.256,,50,HOO,-1.24333,0.0500837,0.0034616,0.941932 beta-lactamase_0_V157L,beta-lactamase_0_157,TEM-1,beta-lactamase_0,P62593,0.941965,NO,157,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.751,-3.066,1.315,,0.308,S,a,0.44,-0.75,3.106,,69.58,BHP,-2.00767,0.0500837,0.00506849,0.941965 beta-lactamase_0_R162L,beta-lactamase_0_162,TEM-1,beta-lactamase_0,P62593,0.941979,NO,162,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.016,-2.541,1.525,,0.124,S,B,1.2,-0.37,1.026,,64.69,ABH,-1.25,0.0500837,0.000561334,0.941979 beta-lactamase_156_M209F,beta-lactamase_156_209,TEM-1,beta-lactamase_156,P62593,0.941989,NO,209,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.442,-2.51,1.068,,,H,A,0.55,-0.97,1.066,,64.69,HHA,-1.52633,0.111618,0.00625021,0.941989 beta-lactamase_2500_A235G,beta-lactamase_2500_235,TEM-1,beta-lactamase_2500,P62593,0.942021,NO,235,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.266,-2.075,0.809,,0.32,E,B,0.46,-0.86,0.891,,50,OHO,-0.89,0.361275,0.00493474,0.942021 kka2_1:8_L152D,kka2_1:8_152,Kka2,kka2_1:8,P00552,0.942044,NO,152,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.521,-3.958,2.437,,0.547,.,A,0.55,1.36,1.442,,63.64,OHH,-1.162,0.100394,0.00674868,0.942044 kka2_1:8_L152D,kka2_1:8_152,Kka2,kka2_1:8,P00552,0.942044,NO,152,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.521,-3.958,2.437,,0.547,.,A,0.55,1.36,1.442,,63.64,OHH,-1.162,0.100394,0.00674868,0.942044 beta-lactamase_F14C,beta-lactamase_14,TEM-1,beta-lactamase,P62593,0.942059,NO,14,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-2.736,-4.754,2.018,,,,,,,1.537,,93.01,HHH,-2.26133,0.221079,0.00277095,0.942059 beta-lactamase_0_A211K,beta-lactamase_0_211,TEM-1,beta-lactamase_0,P62593,0.942066,NO,211,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.896,-3.538,1.642,,0.369,T,A,0.46,-0.69,8.527,8.527,77.62,AHA,-1.94633,0.0500837,0.00648183,0.942066 kka2_1:2_D238G,kka2_1:2_238,Kka2,kka2_1:2,P00552,0.94207,NO,238,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.83,-2.923,0.093,,0.604,H,A,0.75,-0.33,22.789,22.789,92.05,HAB,-2.633,0.295029,0.0113863,0.94207 beta-lactamase_625_L146M,beta-lactamase_625_146,TEM-1,beta-lactamase_625,P62593,0.942104,NO,146,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.462,-4.183,2.721,,0.007,H,A,0.55,-0.56,2.16,,64.69,AHP,-1.656,0.213352,0.00474542,0.942104 kka2_1:8_A9S,kka2_1:8_9,Kka2,kka2_1:8,P00552,0.942142,NO,9,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.079,-2.471,0.392,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.100394,0.00273264,0.942142 kka2_1:8_A9S,kka2_1:8_9,Kka2,kka2_1:8,P00552,0.942142,NO,9,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.079,-2.471,0.392,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.100394,0.00273264,0.942142 beta-lactamase_E237F,beta-lactamase_237,TEM-1,beta-lactamase,P62593,0.942148,NO,237,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.058,-4.397,2.339,5.42877,0.583,S,B,1.62,1.2,2.144,,77.62,OAB,-1.61467,0.221079,0.0048626,0.942148 beta-lactamase_K252W,beta-lactamase_252,TEM-1,beta-lactamase,P62593,0.942148,NO,252,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.94,-5.466,3.526,5.56823,0.766,,B,1.82,1.16,21.796,21.796,67.83,OBO,-2.03333,0.221079,0.00575769,0.942148 PSD95pdz3_N363K,PSD95pdz3_363,PSD95pdz3,PSD95pdz3,P31016,0.942148,NO,363,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-1.41,-2.914,1.504,5.23349,,,,,20.7037,,,,HPO,-1.29433,0.0758425,0.000524014,0.942148 Pab1_V198T,Pab1_198,Pab1,Pab1,P04147,0.942149,NO,198,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.113,-3.014,1.901,,0.008,E,B,0.61,0.91,,,,HHH,-1.32933,0.175299,0.000268557,0.942149 beta-lactamase_0_A215P,beta-lactamase_0_215,TEM-1,beta-lactamase_0,P62593,0.942155,NO,215,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.503,-3.85,2.347,,,,a,0.46,-0.93,0.494,,74.48,HHO,-1.42633,0.0500837,0.00544007,0.942155 beta-lactamase_2500_M180Y,beta-lactamase_2500_180,TEM-1,beta-lactamase_2500,P62593,0.942202,NO,180,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-2.795,-2.93,0.135,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.361275,0.00552048,0.942202 beta-lactamase_39_A225V,beta-lactamase_39_225,TEM-1,beta-lactamase_39,P62593,0.942213,NO,225,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.845,-3.655,1.81,,1,T,B,0.46,-0.38,9.874,9.874,74.48,OHO,-1.39967,0.0495842,0.00465057,0.942213 Pab1_H134F,Pab1_134,Pab1,Pab1,P04147,0.942222,NO,134,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-1.542,-3.95,2.408,,,,,,,,,,HBO,-1.346,0.175299,0.00116356,0.942222 beta-lactamase_K213Y,beta-lactamase_213,TEM-1,beta-lactamase,P62593,0.942264,NO,213,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.81,-4.305,2.495,5.63167,0.67,,A,1.59,0.29,3.924,,67.83,ABH,-1.57767,0.221079,0.00610411,0.942264 PSD95pdz3_I341C,PSD95pdz3_341,PSD95pdz3,PSD95pdz3,P31016,0.942282,NO,341,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.63,-4.319,2.689,5.73946,,,,,10.3187,,,,HHH,-1.50033,0.0758425,0.000824087,0.942282 kka2_1:4_S204C,kka2_1:4_204,Kka2,kka2_1:4,P00552,0.942287,NO,204,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.353,-4.762,3.409,,0.144,E,A,0.27,-1.2,2.442,,65.53,HPO,-0.953333,0.168804,0.00881794,0.942287 beta-lactamase_G236A,beta-lactamase_236,TEM-1,beta-lactamase,P62593,0.942291,NO,236,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.784,-2.29,1.506,4.7915,0.241,,b,0.23,-0.59,1.883,,64.69,HOA,-1.36933,0.221079,0.00162372,0.942291 kka2_1:4_T73Y,kka2_1:4_73,Kka2,kka2_1:4,P00552,0.94231,NO,73,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.51,-3.328,0.818,,0.309,H,A,0.22,0.35,1.53,,56.06,PPO,-2.02333,0.168804,0.00628605,0.94231 beta-lactamase_625_D83T,beta-lactamase_625_83,TEM-1,beta-lactamase_625,P62593,0.942321,NO,83,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.066,-3.464,2.398,,0.354,H,A,0.75,0.22,0.239,,48.95,HAH,-1.34733,0.213352,0.00205968,0.942321 beta-lactamase_I206E,beta-lactamase_206,TEM-1,beta-lactamase,P62593,0.942336,NO,206,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-2.429,-2.747,0.318,5.3727,0.173,H,A,1,-0.34,2.061,,77.62,HHA,-1.805,0.221079,0.00528934,0.942336 beta-lactamase_2500_P172R,beta-lactamase_2500_172,TEM-1,beta-lactamase_2500,P62593,0.942371,NO,172,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.998,-3.96,2.962,,0.639,T,b,0.52,0.24,4.99,,74.48,HOP,-2.03067,0.361275,0.00312594,0.942371 beta-lactamase_0_G39T,beta-lactamase_0_39,TEM-1,beta-lactamase_0,P62593,0.942373,NO,39,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.864,-2.931,1.067,,0.701,T,L,0.29,0.47,4.111,,77.62,HOH,-1.53633,0.0500837,0.00487611,0.942373 beta-lactamase_39_A230Q,beta-lactamase_39_230,TEM-1,beta-lactamase_39,P62593,0.942382,NO,230,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.154,-4.025,2.871,,0.01,E,B,0.46,-1.17,1.171,,50,HHA,-1.079,0.0495842,0.00516841,0.942382 beta-lactamase_625_G141N,beta-lactamase_625_141,TEM-1,beta-lactamase_625,P62593,0.942433,NO,141,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.828,-3.472,2.644,,0.575,T,l,0.29,-0.28,0.198,,64.69,HOO,-1.08933,0.213352,0.0012419,0.942433 beta-lactamase_625_I244F,beta-lactamase_625_244,TEM-1,beta-lactamase_625,P62593,0.942435,NO,244,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.555,-3.842,2.287,,,E,B,0.48,-0.84,2.061,,77.62,OHH,-1.385,0.213352,0.00605379,0.942435 beta-lactamase_39_K144P,beta-lactamase_39_144,TEM-1,beta-lactamase_39,P62593,0.942441,NO,144,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-2.388,-2.633,0.245,,0.863,H,A,2.34,1.27,14.556,14.556,77.62,OBA,-1.904,0.0495842,0.00481141,0.942441 beta-lactamase_R238A,beta-lactamase_238,TEM-1,beta-lactamase,P62593,0.942458,NO,238,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.002,-3.373,1.371,5.87663,0.564,T,L,0.45,1.09,4.195,,72.73,ABO,-1.62633,0.221079,0.00743256,0.942458 beta-lactamase_0_L55K,beta-lactamase_0_55,TEM-1,beta-lactamase_0,P62593,0.942459,NO,55,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.86,-3.791,1.931,,0.372,E,A,0.55,-0.36,1.967,,63.99,HHA,-2.247,0.0500837,0.00403741,0.942459 kka2_1:1_M178Q,kka2_1:1_178,Kka2,kka2_1:1,P00552,0.942467,NO,178,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-3.206,-2.478,-0.728,,0.554,.,b,0.55,0.68,3.152,,71.59,BHO,-2.154,0.520039,0.00717253,0.942467 beta-lactamase_2500_K32N,beta-lactamase_2500_32,TEM-1,beta-lactamase_2500,P62593,0.942477,NO,32,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.984,-2.965,0.981,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.361275,0.00401283,0.942477 beta-lactamase_0_R118G,beta-lactamase_0_118,TEM-1,beta-lactamase_0,P62593,0.94249,NO,118,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.413,-1.757,-0.656,,0.457,H,A,1.2,1.39,3.961,,77.62,HBA,-1.785,0.0500837,0.00538794,0.94249 kka2_1:4_A35P,kka2_1:4_35,Kka2,kka2_1:4,P00552,0.942491,NO,35,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.127,-4.029,1.902,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.168804,0.00630016,0.942491 kka2_1:4_D101T,kka2_1:4_101,Kka2,kka2_1:4,P00552,0.942502,NO,101,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.028,-3.464,2.436,,0.213,E,B,0.75,-1.24,8.707,,63.64,PAH,-1.534,0.168804,0.00423361,0.942502 beta-lactamase_E56R,beta-lactamase_56,TEM-1,beta-lactamase,P62593,0.942505,NO,56,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.043,-3.679,1.636,5.65281,0.198,E,B,0.52,0.31,2.022,,72.73,HAP,-1.94033,0.221079,0.00238534,0.942505 beta-lactamase_0_N168D,beta-lactamase_0_168,TEM-1,beta-lactamase_0,P62593,0.942506,NO,168,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-1.029,-3.143,2.114,,0.113,G,A,0.61,-0.4,0.881,,44.41,HPA,-1.13233,0.0500837,0.00288667,0.942506 beta-lactamase_S57N,beta-lactamase_57,TEM-1,beta-lactamase,P62593,0.942507,NO,57,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.918,-2.953,1.035,5.64201,0.352,E,B,0.25,-0.18,1.971,,72.73,APH,-2.29167,0.221079,0.00492804,0.942507 beta-lactamase_R41L,beta-lactamase_41,TEM-1,beta-lactamase,P62593,0.942529,NO,41,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-0.942,-3.384,2.442,5.69185,0.321,E,B,0.91,-0.07,4.357,,65.03,HBH,-1.30267,0.221079,0.00123327,0.942529 Pab1_V171C,Pab1_171,Pab1,Pab1,P04147,0.94254,NO,171,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.113,-4.454,3.341,,0.008,E,b,0.23,-0.34,,,,HHB,-1.19733,0.175299,0.000298662,0.94254 kka2_1:8_C77A,kka2_1:8_77,Kka2,kka2_1:8,P00552,0.942553,NO,77,C,A,CA,Special,Hydrophobic,5.07,6,0.93,195,121,89,-32,108.5,88.6,-19.9,-1.477,-1.773,0.296,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.100394,0.00441216,0.942553 kka2_1:8_C77A,kka2_1:8_77,Kka2,kka2_1:8,P00552,0.942553,NO,77,C,A,CA,Special,Hydrophobic,5.07,6,0.93,195,121,89,-32,108.5,88.6,-19.9,-1.477,-1.773,0.296,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.100394,0.00441216,0.942553 beta-lactamase_625_L100Y,beta-lactamase_625_100,TEM-1,beta-lactamase_625,P62593,0.942559,NO,100,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.218,-2.879,1.661,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.213352,0.00413885,0.942559 beta-lactamase_0_L191S,beta-lactamase_0_191,TEM-1,beta-lactamase_0,P62593,0.94256,NO,191,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.087,-3.562,2.475,,,H,A,0.55,0.09,12.255,12.255,63.29,BHH,-1.445,0.0500837,0.00263549,0.94256 Pab1_D151T,Pab1_151,Pab1,Pab1,P04147,0.942564,NO,151,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.399,-2.468,0.069,,,,,,,,,,OAH,-1.51767,0.175299,0.00228155,0.942564 beta-lactamase_0_L160C,beta-lactamase_0_160,TEM-1,beta-lactamase_0,P62593,0.94257,NO,160,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.977,-4.68,3.703,,0.022,,B,0.55,-0.6,0.68,,44.41,BHA,-0.936,0.0500837,0.00193775,0.94257 beta-lactamase_2500_R275C,beta-lactamase_2500_275,TEM-1,beta-lactamase_2500,P62593,0.942594,NO,275,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.361275,0.0141984,0.942594 gb1_T281C,gb1_281,gb1,gb1,P06654,0.942607,NO,281,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.828,-4.55,2.722,,,,,,,1.038,,35.71,HPA,-1.63667,0.177985,0.00284418,0.942607 beta-lactamase_2500_P217T,beta-lactamase_2500_217,TEM-1,beta-lactamase_2500,P62593,0.942611,NO,217,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-2.062,-2.679,0.617,,0.496,I,A,0.52,-0.33,0.431,,74.48,OOH,-1.64333,0.361275,0.00463211,0.942611 beta-lactamase_2500_G39V,beta-lactamase_2500_39,TEM-1,beta-lactamase_2500,P62593,0.942629,NO,39,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.864,-3.813,1.949,,0.701,T,L,0.29,0.47,29.926,29.926,77.62,HOH,-1.53633,0.361275,0.00487611,0.942629 beta-lactamase_0_L192E,beta-lactamase_0_192,TEM-1,beta-lactamase_0,P62593,0.942636,NO,192,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.254,-3.893,2.639,,0.095,H,A,0.55,0.35,1.756,,60.14,HHP,-1.41833,0.0500837,0.00558728,0.942636 beta-lactamase_G194K,beta-lactamase_194,TEM-1,beta-lactamase,P62593,0.942642,NO,194,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.396,-3.557,2.161,5.46622,0.276,S,b,0.77,0.36,3.593,,67.83,POA,-1.832,0.221079,0.00392163,0.942642 beta-lactamase_N98P,beta-lactamase_98,TEM-1,beta-lactamase,P62593,0.942642,NO,98,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-2.973,-3.946,0.973,6.59973,0.963,G,A,1.07,1.35,1.332,,77.62,PPA,-2.07867,0.221079,0.00505389,0.942642 beta-lactamase_Q204Y,beta-lactamase_204,TEM-1,beta-lactamase,P62593,0.942642,NO,204,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-1.382,-4.071,2.689,5.46394,0.204,H,A,0.12,0.09,1.707,,66.08,PPH,-1.49067,0.221079,0.00364106,0.942642 beta-lactamase_0_V42C,beta-lactamase_0_42,TEM-1,beta-lactamase_0,P62593,0.942654,NO,42,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.564,-4.789,3.225,,0.017,E,B,0.44,-0.51,1.659,,63.99,BHO,-1.042,0.0500837,0.00404515,0.942654 beta-lactamase_0_D36T,beta-lactamase_0_36,TEM-1,beta-lactamase_0,P62593,0.942659,NO,36,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.732,-2.57,-0.162,,0.555,H,A,0.75,1.17,13.689,13.689,77.62,AAP,-1.91167,0.0500837,0.00476483,0.942659 beta-lactamase_2500_A268K,beta-lactamase_2500_268,TEM-1,beta-lactamase_2500,P62593,0.942674,NO,268,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.361275,0.0102525,0.942674 beta-lactamase_L136I,beta-lactamase_136,TEM-1,beta-lactamase,P62593,0.942684,NO,136,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.232,-1.874,0.642,5.31114,,H,A,2.89,-0.34,1.539,,48.95,HHH,-1.088,0.221079,0.00442304,0.942684 Pab1_G163V,Pab1_163,Pab1,Pab1,P04147,0.942725,NO,163,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.809,-3.571,2.762,,0.356,B,g,,0.55,,,,POB,-1.80667,0.175299,0.00030953,0.942725 beta-lactamase_T267I,beta-lactamase_267,TEM-1,beta-lactamase,P62593,0.942733,NO,267,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.308,-3.131,0.823,5.28263,0.54,,B,0.69,-0.14,0.374,,73.78,HPH,-1.9,0.221079,0.0102128,0.942733 PSD95pdz3_A382I,PSD95pdz3_382,PSD95pdz3,PSD95pdz3,P31016,0.942747,NO,382,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.307,-3.242,1.935,5.30282,,,,,22.472,,,,PHO,-1.24167,0.0758425,0.000249256,0.942747 beta-lactamase_L188T,beta-lactamase_188,TEM-1,beta-lactamase,P62593,0.94276,NO,188,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.166,-3.522,2.356,5.55434,,H,A,1.07,-0.3,1.574,,60.14,PHB,-1.47033,0.221079,0.00295687,0.94276 beta-lactamase_0_S233I,beta-lactamase_0_233,TEM-1,beta-lactamase_0,P62593,0.942761,NO,233,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.886,-3.784,1.898,,0.016,E,B,0.27,-1.01,3.579,,77.62,BPO,-1.17267,0.0500837,0.00311415,0.942761 beta-lactamase_H24Y,beta-lactamase_24,TEM-1,beta-lactamase,P62593,0.942769,NO,24,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-2.481,-4.052,1.571,5.82767,,,,,,2.708,,93.01,HBO,-1.85167,0.221079,0.00238894,0.942769 beta-lactamase_0_V78H,beta-lactamase_0_78,TEM-1,beta-lactamase_0,P62593,0.94278,NO,78,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.459,-5.015,3.556,,,H,A,0.44,-0.47,16.615,16.615,63.64,HHH,-1.17833,0.0500837,0.00492501,0.94278 beta-lactamase_2500_G253L,beta-lactamase_2500_253,TEM-1,beta-lactamase_2500,P62593,0.942787,NO,253,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.361275,0.00786358,0.942787 kka2_1:8_A41V,kka2_1:8_41,Kka2,kka2_1:8,P00552,0.942807,NO,41,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.879,-2.914,1.035,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.100394,0.00543332,0.942807 kka2_1:8_A41V,kka2_1:8_41,Kka2,kka2_1:8,P00552,0.942807,NO,41,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.879,-2.914,1.035,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.100394,0.00543332,0.942807 beta-lactamase_K252D,beta-lactamase_252,TEM-1,beta-lactamase,P62593,0.942827,NO,252,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.94,-3.575,1.635,5.56823,0.766,,B,1.82,1.16,21.796,21.796,67.83,OBO,-2.03333,0.221079,0.00575769,0.942827 beta-lactamase_39_R159I,beta-lactamase_39_159,TEM-1,beta-lactamase_39,P62593,0.942835,NO,159,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-0.94,-4.036,3.096,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.0495842,0.00108472,0.942835 beta-lactamase_0_S96N,beta-lactamase_0_96,TEM-1,beta-lactamase_0,P62593,0.942837,NO,96,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.27,-3.037,0.767,,0.368,,b,0.27,0.39,2.516,,73.78,HPP,-2.019,0.0500837,0.00551835,0.942837 kka2_1:2_L94C,kka2_1:2_94,Kka2,kka2_1:2,P00552,0.942851,NO,94,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.618,-4.788,3.17,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.295029,0.00520888,0.942851 beta-lactamase_0_G141A,beta-lactamase_0_141,TEM-1,beta-lactamase_0,P62593,0.942865,NO,141,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.828,-2.988,2.16,,0.575,T,l,0.29,-0.28,0.722,,64.69,HOO,-1.08933,0.0500837,0.0012419,0.942865 beta-lactamase_0_E62P,beta-lactamase_0_62,TEM-1,beta-lactamase_0,P62593,0.942876,NO,62,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.193,-3.775,2.582,,0.342,S,B,1.04,-0.3,5.784,,73.08,AAB,-1.417,0.0500837,0.00264802,0.942876 beta-lactamase_P60N,beta-lactamase_60,TEM-1,beta-lactamase,P62593,0.942882,NO,60,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-2.469,-3.804,1.335,5.51353,0.256,T,A,0.73,-0.56,3.653,,77.62,BOA,-1.97633,0.221079,0.00521318,0.942882 beta-lactamase_39_A268N,beta-lactamase_39_268,TEM-1,beta-lactamase_39,P62593,0.942896,NO,268,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.0495842,0.0102525,0.942896 kka2_1:8_N58Y,kka2_1:8_58,Kka2,kka2_1:8,P00552,0.942905,NO,58,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-2.641,-4.48,1.839,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.100394,0.00793425,0.942905 kka2_1:8_N58Y,kka2_1:8_58,Kka2,kka2_1:8,P00552,0.942905,NO,58,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-2.641,-4.48,1.839,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.100394,0.00793425,0.942905 beta-lactamase_0_L223A,beta-lactamase_0_223,TEM-1,beta-lactamase_0,P62593,0.942945,NO,223,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.055,-3.102,2.047,,0.27,,B,0.55,0.09,1.633,,74.48,HHO,-1.35033,0.0500837,0.00372793,0.942945 beta-lactamase_H285M,beta-lactamase_285,TEM-1,beta-lactamase,P62593,0.942984,NO,285,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-1.845,-4.514,2.669,5.64289,0.312,T,a,0.35,0.64,1.401,,72.73,BBH,-1.64567,0.221079,0.101555,0.942984 beta-lactamase_2500_M180G,beta-lactamase_2500_180,TEM-1,beta-lactamase_2500,P62593,0.942992,NO,180,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-2.795,-3.389,0.594,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.361275,0.00552048,0.942992 Pab1_L191E,Pab1_191,Pab1,Pab1,P04147,0.942996,NO,191,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.2,-3.703,2.503,,0.204,E,B,,2.24,,,,HHP,-1.20133,0.175299,0.000583797,0.942996 kka2_1:4_R121D,kka2_1:4_121,Kka2,kka2_1:4,P00552,0.942998,NO,121,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.552,-3.714,2.162,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.168804,0.00523326,0.942998 beta-lactamase_0_M209G,beta-lactamase_0_209,TEM-1,beta-lactamase_0,P62593,0.943026,NO,209,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.442,-3.732,2.29,,,H,A,0.55,-0.97,3.876,,64.69,HHA,-1.52633,0.0500837,0.00625021,0.943026 beta-lactamase_0_K286W,beta-lactamase_0_286,TEM-1,beta-lactamase_0,P62593,0.943045,NO,286,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.111,-3.724,2.613,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.0500837,,0.943045 beta-lactamase_39_A230R,beta-lactamase_39_230,TEM-1,beta-lactamase_39,P62593,0.943051,NO,230,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.154,-3.858,2.704,,0.01,E,B,0.46,-1.17,1.171,,50,HHA,-1.079,0.0495842,0.00516841,0.943051 gb1_K230A,gb1_230,gb1,gb1,P06654,0.943066,NO,230,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.701,-2.995,1.294,,,,,,,0.166,,11.83,HBH,-1.52867,0.177985,0.00331703,0.943066 beta-lactamase_2500_W163T,beta-lactamase_2500_163,TEM-1,beta-lactamase_2500,P62593,0.94308,NO,163,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-1.843,-2.765,0.922,,0.467,,B,0.47,-0.5,32.624,32.624,63.99,BHA,-1.269,0.361275,0.00418955,0.94308 kka2_1:1_P109L,kka2_1:1_109,Kka2,kka2_1:1,P00552,0.943085,NO,109,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.412,-3.58,2.168,,0.376,H,A,0.52,-1.25,18.506,18.506,65.53,HOH,-1.84567,0.520039,0.0070929,0.943085 beta-lactamase_0_G52N,beta-lactamase_0_52,TEM-1,beta-lactamase_0,P62593,0.9431,NO,52,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.149,-3.58,2.431,,0.299,,l,0.29,-0.04,1.164,,64.69,POB,-1.66267,0.0500837,0.00340138,0.9431 beta-lactamase_625_T263E,beta-lactamase_625_263,TEM-1,beta-lactamase_625,P62593,0.943134,NO,263,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.213352,0.0110582,0.943134 WW_domain_A180S,WW_domain_180,Yap65,WW_domain,P46937,0.943147,NO,180,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.242,-2.776,1.534,6.02829,,,,,,0.627,,23.61,HHB,-1.37767,0.153962,0.00413929,0.943147 kka2_1:4_E17F,kka2_1:4_17,Kka2,kka2_1:4,P00552,0.943154,NO,17,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.154,-4.494,2.34,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.168804,0.00688738,0.943154 beta-lactamase_156_V78Y,beta-lactamase_156_78,TEM-1,beta-lactamase_156,P62593,0.943181,NO,78,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.459,-4.112,2.653,,,H,A,0.44,-0.47,1.132,,63.64,HHH,-1.17833,0.111618,0.00492501,0.943181 beta-lactamase_0_L100S,beta-lactamase_0_100,TEM-1,beta-lactamase_0,P62593,0.943219,NO,100,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.218,-3.715,2.497,,0.343,,B,0.55,0.13,1.373,,63.29,AHH,-1.23467,0.0500837,0.00413885,0.943219 beta-lactamase_39_D113N,beta-lactamase_39_113,TEM-1,beta-lactamase_39,P62593,0.943224,NO,113,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.829,-3.682,1.853,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.0495842,0.00474112,0.943224 kka2_1:8_R239C,kka2_1:8_239,Kka2,kka2_1:8,P00552,0.943237,NO,239,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.949,-5.104,2.155,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.100394,0.00835326,0.943237 kka2_1:8_R239C,kka2_1:8_239,Kka2,kka2_1:8,P00552,0.943237,NO,239,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.949,-5.104,2.155,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.100394,0.00835326,0.943237 beta-lactamase_156_V42Y,beta-lactamase_156_42,TEM-1,beta-lactamase_156,P62593,0.943245,NO,42,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.564,-4.12,2.556,,0.017,E,B,0.44,-0.51,2.576,,63.99,BHO,-1.042,0.111618,0.00404515,0.943245 kka2_1:8_L60P,kka2_1:8_60,Kka2,kka2_1:8,P00552,0.943296,NO,60,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.997,-4.194,3.197,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.100394,0.00262176,0.943296 kka2_1:8_L60P,kka2_1:8_60,Kka2,kka2_1:8,P00552,0.943296,NO,60,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.997,-4.194,3.197,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.100394,0.00262176,0.943296 beta-lactamase_0_D177A,beta-lactamase_0_177,TEM-1,beta-lactamase_0,P62593,0.943308,NO,177,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.967,-2.529,1.562,,0.006,T,L,0.75,-1.02,3.536,,64.69,BAP,-0.873667,0.0500837,0.000864022,0.943308 beta-lactamase_L150F,beta-lactamase_150,TEM-1,beta-lactamase,P62593,0.943317,NO,150,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.326,-3.884,2.558,5.15566,,H,A,1.75,-0.2,1.615,,62.94,HHB,-1.86167,0.221079,0.00463171,0.943317 beta-lactamase_39_M180R,beta-lactamase_39_180,TEM-1,beta-lactamase_39,P62593,0.943331,NO,180,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-2.795,-3.843,1.048,,0.242,,B,0.55,-0.94,3.579,,77.62,PHO,-1.56433,0.0495842,0.00552048,0.943331 beta-lactamase_L137Y,beta-lactamase_137,TEM-1,beta-lactamase,P62593,0.943336,NO,137,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.03,-4.002,2.972,5.20117,,H,A,1.07,-0.38,0.674,,42.31,HHP,-1.58933,0.221079,0.00278599,0.943336 beta-lactamase_2500_R239A,beta-lactamase_2500_239,TEM-1,beta-lactamase_2500,P62593,0.943359,NO,239,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.361275,0.00213852,0.943359 kka2_1:4_A71V,kka2_1:4_71,Kka2,kka2_1:4,P00552,0.943367,NO,71,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.824,-3.693,1.869,,0.553,H,A,0.46,0.08,5.76,,64.39,HHP,-1.74033,0.168804,0.00727707,0.943367 hsp90_M589I,hsp90_589,hsp90,hsp90,P02829,0.94338,NO,589,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-3.858,-2.939,0,4.72723,0.032,H,A,0.84,0.31,,,,PHA,-3.24233,0.368192,0.000222939,0.94338 PSD95pdz3_A390I,PSD95pdz3_390,PSD95pdz3,PSD95pdz3,P31016,0.943381,NO,390,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.307,-3.242,1.935,5.03823,,,,,12.46,,,,HHP,-1.54467,0.0758425,0.00104603,0.943381 beta-lactamase_156_M209G,beta-lactamase_156_209,TEM-1,beta-lactamase_156,P62593,0.943397,NO,209,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.442,-3.732,2.29,,,H,A,0.55,-0.97,1.066,,64.69,HHA,-1.52633,0.111618,0.00625021,0.943397 kka2_1:8_L19T,kka2_1:8_19,Kka2,kka2_1:8,P00552,0.943436,NO,19,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.254,-3.645,2.391,,0.08,T,A,1.59,-0.26,2.044,,65.53,BHH,-2.221,0.100394,0.00620703,0.943436 kka2_1:8_L19T,kka2_1:8_19,Kka2,kka2_1:8,P00552,0.943436,NO,19,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.254,-3.645,2.391,,0.08,T,A,1.59,-0.26,2.044,,65.53,BHH,-2.221,0.100394,0.00620703,0.943436 Pab1_E181K,Pab1_181,Pab1,Pab1,P04147,0.943529,NO,181,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.767,-3.229,1.462,,,,,,,1.395,,73.83,BAH,-1.575,0.175299,0.00107557,0.943529 beta-lactamase_39_Q203M,beta-lactamase_39_203,TEM-1,beta-lactamase_39,P62593,0.943538,NO,203,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.168,-4.659,2.491,,0.47,H,A,0.64,-0.38,1.453,,65.38,BPP,-1.614,0.0495842,0.00631514,0.943538 Ubiquitin_A28E,Ubiquitin_28,Uba1,Ubiquitin,P0CG48,0.943548,NO,28,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.895,-2.423,0.528,4.73736,0.369,H,A,,-0.11,,,,BHB,-1.47667,0.205827,0.000842053,0.943548 Ubiquitin_A28L,Ubiquitin_28,Uba1,Ubiquitin,P0CG48,0.943548,NO,28,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.895,-3.429,1.534,4.73736,0.369,H,A,,-0.11,,,,BHB,-1.47667,0.205827,0.000842053,0.943548 Ubiquitin_D21F,Ubiquitin_21,Uba1,Ubiquitin,P0CG48,0.943548,NO,21,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.193,-4.089,2.896,4.96432,0.165,,B,0.23,-0.53,1.013,,71.82,PAP,-1.35867,0.205827,0.000465257,0.943548 Ubiquitin_D21I,Ubiquitin_21,Uba1,Ubiquitin,P0CG48,0.943548,NO,21,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.193,-3.966,2.773,4.96432,0.165,,B,0.23,-0.53,1.013,,71.82,PAP,-1.35867,0.205827,0.000465257,0.943548 Ubiquitin_D52F,Ubiquitin_52,Uba1,Ubiquitin,P0CG48,0.943548,NO,52,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.43,-2.94,1.51,4.75143,0.421,T,A,,0.79,,,,AAO,-1.50267,0.205827,0.000806517,0.943548 Ubiquitin_E51A,Ubiquitin_51,Uba1,Ubiquitin,P0CG48,0.943548,NO,51,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.534,-3.149,1.615,5.36711,0.545,,B,,0.72,,,,HAA,-1.357,0.205827,0.000868134,0.943548 Ubiquitin_E51C,Ubiquitin_51,Uba1,Ubiquitin,P0CG48,0.943548,NO,51,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.534,-5.179,3.645,5.36711,0.545,,B,,0.72,,,,HAA,-1.357,0.205827,0.000868134,0.943548 Ubiquitin_E51S,Ubiquitin_51,Uba1,Ubiquitin,P0CG48,0.943548,NO,51,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.534,-2.436,0.902,5.36711,0.545,,B,,0.72,,,,HAA,-1.357,0.205827,0.000868134,0.943548 Ubiquitin_E64V,Ubiquitin_64,Uba1,Ubiquitin,P0CG48,0.943548,NO,64,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.763,-2.957,1.194,5.084,0.54,T,l,,0.79,,,,BAP,-1.64433,0.205827,0.000817406,0.943548 Ubiquitin_E64W,Ubiquitin_64,Uba1,Ubiquitin,P0CG48,0.943548,NO,64,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.763,-3.402,1.639,5.084,0.54,T,l,,0.79,,,,BAP,-1.64433,0.205827,0.000817406,0.943548 Ubiquitin_G35N,Ubiquitin_35,Uba1,Ubiquitin,P0CG48,0.943548,NO,35,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.171,-3.618,2.447,4.96213,0.713,,L,,0.2,,,,AOH,-1.314,0.205827,0.000648878,0.943548 Ubiquitin_I13N,Ubiquitin_13,Uba1,Ubiquitin,P0CG48,0.943548,NO,13,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.554,-4.116,2.562,5.19411,0.038,E,B,,-0.2,,,,PHP,-1.48,0.205827,0.000716423,0.943548 Ubiquitin_I13S,Ubiquitin_13,Uba1,Ubiquitin,P0CG48,0.943548,NO,13,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.554,-3.633,2.079,5.19411,0.038,E,B,,-0.2,,,,PHP,-1.48,0.205827,0.000716423,0.943548 Ubiquitin_I23P,Ubiquitin_23,Uba1,Ubiquitin,P0CG48,0.943548,NO,23,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.325,-4.077,2.752,4.67534,,H,A,0.01,-0.93,0.515,,52.12,PHA,-1.54033,0.205827,0.000621252,0.943548 Ubiquitin_I44V,Ubiquitin_44,Uba1,Ubiquitin,P0CG48,0.943548,NO,44,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.566,-2.228,0.662,4.71256,,E,B,0.27,-1.17,5.26,,39.71,HHH,-1.38567,0.205827,0.000613305,0.943548 Ubiquitin_K11M,Ubiquitin_11,Uba1,Ubiquitin,P0CG48,0.943548,NO,11,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.354,-4.537,3.183,5.16813,0.401,,B,2.81,0.84,0.335,,25.84,OBP,-1.346,0.205827,0.000535553,0.943548 Ubiquitin_K11Q,Ubiquitin_11,Uba1,Ubiquitin,P0CG48,0.943548,NO,11,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.354,-3.58,2.226,5.16813,0.401,,B,2.81,0.84,0.335,,25.84,OBP,-1.346,0.205827,0.000535553,0.943548 Ubiquitin_K11R,Ubiquitin_11,Uba1,Ubiquitin,P0CG48,0.943548,NO,11,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.354,-2.547,1.193,5.16813,0.401,,B,2.81,0.84,0.335,,25.84,OBP,-1.346,0.205827,0.000535553,0.943548 Ubiquitin_K33G,Ubiquitin_33,Uba1,Ubiquitin,P0CG48,0.943548,NO,33,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.283,-3.537,2.254,5.08526,0.64,H,A,1.82,1.2,1.509,,51.09,ABA,-1.34267,0.205827,0.000712743,0.943548 Ubiquitin_K33N,Ubiquitin_33,Uba1,Ubiquitin,P0CG48,0.943548,NO,33,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.283,-3.678,2.395,5.08526,0.64,H,A,1.82,1.2,1.509,,51.09,ABA,-1.34267,0.205827,0.000712743,0.943548 Ubiquitin_K33Q,Ubiquitin_33,Uba1,Ubiquitin,P0CG48,0.943548,NO,33,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.283,-3.673,2.39,5.08526,0.64,H,A,1.82,1.2,1.509,,51.09,ABA,-1.34267,0.205827,0.000712743,0.943548 Ubiquitin_K63D,Ubiquitin_63,Uba1,Ubiquitin,P0CG48,0.943548,NO,63,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.635,-2.5,0.865,5.08297,0.721,T,B,,0.59,,,,PBA,-1.74467,0.205827,0.000607964,0.943548 Ubiquitin_K63E,Ubiquitin_63,Uba1,Ubiquitin,P0CG48,0.943548,NO,63,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.635,-2.432,0.797,5.08297,0.721,T,B,,0.59,,,,PBA,-1.74467,0.205827,0.000607964,0.943548 Ubiquitin_K63R,Ubiquitin_63,Uba1,Ubiquitin,P0CG48,0.943548,NO,63,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.635,-2.573,0.938,5.08297,0.721,T,B,,0.59,,,,PBA,-1.74467,0.205827,0.000607964,0.943548 Ubiquitin_K63Y,Ubiquitin_63,Uba1,Ubiquitin,P0CG48,0.943548,NO,63,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.635,-4.231,2.596,5.08297,0.721,T,B,,0.59,,,,PBA,-1.74467,0.205827,0.000607964,0.943548 Ubiquitin_K6Q,Ubiquitin_6,Uba1,Ubiquitin,P0CG48,0.943548,NO,6,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.093,-3.418,2.325,4.84211,0.35,E,B,1.82,-0.62,1.502,,71.82,HBP,-1.36133,0.205827,0.000784795,0.943548 Ubiquitin_L71M,Ubiquitin_71,Uba1,Ubiquitin,P0CG48,0.943548,NO,71,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.647,-4.343,2.696,5.02588,0.591,E,B,2.89,-0.69,4.365,,34.31,HHB,-1.85167,0.205827,0.000949314,0.943548 Ubiquitin_N25Y,Ubiquitin_25,Uba1,Ubiquitin,P0CG48,0.943548,NO,25,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-1.95,-4.244,2.294,4.76563,0.444,H,A,0.09,0,2.3,,31.09,APH,-1.741,0.205827,0.00071919,0.943548 Ubiquitin_Q62W,Ubiquitin_62,Uba1,Ubiquitin,P0CG48,0.943548,NO,62,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-1.836,-5.419,3.583,5.33616,0.762,,B,,0.79,,,,HPB,-1.66167,0.205827,0.00068944,0.943548 Ubiquitin_T22H,Ubiquitin_22,Uba1,Ubiquitin,P0CG48,0.943548,NO,22,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.344,-4.565,3.221,4.54389,0.237,B,B,,-0.75,,,,APH,-1.28733,0.205827,0.000535592,0.943548 Ubiquitin_T22M,Ubiquitin_22,Uba1,Ubiquitin,P0CG48,0.943548,NO,22,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.344,-4.498,3.154,4.54389,0.237,B,B,,-0.75,,,,APH,-1.28733,0.205827,0.000535592,0.943548 Ubiquitin_T22P,Ubiquitin_22,Uba1,Ubiquitin,P0CG48,0.943548,NO,22,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.344,-3.788,2.444,4.54389,0.237,B,B,,-0.75,,,,APH,-1.28733,0.205827,0.000535592,0.943548 Ubiquitin_T9C,Ubiquitin_9,Uba1,Ubiquitin,P0CG48,0.943548,NO,9,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.409,-2.658,1.249,5.24336,0.777,T,A,2.12,-0.12,2.705,,29.93,HPO,-1.50933,0.205827,0.000630716,0.943548 Ubiquitin_T9V,Ubiquitin_9,Uba1,Ubiquitin,P0CG48,0.943548,NO,9,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.409,-2.578,1.169,5.24336,0.777,T,A,2.12,-0.12,2.705,,29.93,HPO,-1.50933,0.205827,0.000630716,0.943548 Ubiquitin_V5V,Ubiquitin_5,Uba1,Ubiquitin,P0CG48,0.943548,NO,5,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.576,-1.576,,4.75677,,E,B,,-0.82,,,,HHB,-1.401,0.205827,0.000796998,0.943548 Ubiquitin_Y59N,Ubiquitin_59,Uba1,Ubiquitin,P0CG48,0.943548,NO,59,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-1.307,-2.827,1.52,5.05599,0.072,G,A,0.43,-0.74,2.566,,24.53,AHP,-1.568,0.205827,0.000775084,0.943548 beta-lactamase_A84F,beta-lactamase_84,TEM-1,beta-lactamase,P62593,0.943577,NO,84,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.651,-4.366,2.715,5.28927,0.65,T,A,0.52,0.96,1.863,,68.18,AHO,-1.24267,0.221079,0.00503822,0.943577 kka2_1:4_A191S,kka2_1:4_191,Kka2,kka2_1:4,P00552,0.943602,NO,191,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.831,-3.052,2.221,,,.,b,0.46,-0.94,2.046,,50,AHO,-0.868667,0.168804,0.00338807,0.943602 Pab1_L190K,Pab1_190,Pab1,Pab1,P04147,0.943623,NO,190,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.325,-3.457,2.132,,0.489,E,B,,2.59,,,,HHH,-1.31033,0.175299,0.00132347,0.943623 beta-lactamase_39_F64C,beta-lactamase_39_64,TEM-1,beta-lactamase_39,P62593,0.943631,NO,64,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-0.841,-4.862,4.021,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.0495842,0.000947691,0.943631 beta-lactamase_P253F,beta-lactamase_253,TEM-1,beta-lactamase,P62593,0.943662,NO,253,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-2.253,-4.442,2.189,5.24842,0.308,,B,0.73,-0.46,2.293,,73.08,BOP,-2.10633,0.221079,0.00786358,0.943662 beta-lactamase_2500_I285L,beta-lactamase_2500_285,TEM-1,beta-lactamase_2500,P62593,0.943665,NO,285,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.361275,0.101555,0.943665 beta-lactamase_0_R92M,beta-lactamase_0_92,TEM-1,beta-lactamase_0,P62593,0.943672,NO,92,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.718,-3.339,1.621,,0.479,E,B,1.2,1.36,2.331,,65.38,BBH,-1.50367,0.0500837,0.00429626,0.943672 beta-lactamase_0_K144G,beta-lactamase_0_144,TEM-1,beta-lactamase_0,P62593,0.943693,NO,144,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-2.388,-2.818,0.43,,0.863,H,A,2.34,1.27,5.696,,77.62,OBA,-1.904,0.0500837,0.00481141,0.943693 Pab1_A178Q,Pab1_178,Pab1,Pab1,P04147,0.9437,NO,178,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.579,-3.802,2.223,,0.019,H,A,0.64,0.64,2.7,,81.63,OHH,-1.61067,0.175299,0.00160192,0.9437 beta-lactamase_2500_K254W,beta-lactamase_2500_254,TEM-1,beta-lactamase_2500,P62593,0.943713,NO,254,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.361275,0.00369,0.943713 beta-lactamase_L137I,beta-lactamase_137,TEM-1,beta-lactamase,P62593,0.943721,NO,137,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.03,-2.064,1.034,5.20117,,H,A,1.07,-0.38,0.674,,42.31,HHP,-1.58933,0.221079,0.00278599,0.943721 beta-lactamase_39_Q203N,beta-lactamase_39_203,TEM-1,beta-lactamase_39,P62593,0.943722,NO,203,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.168,-3.727,1.559,,0.47,H,A,0.64,-0.38,1.453,,65.38,BPP,-1.614,0.0495842,0.00631514,0.943722 beta-lactamase_39_T138F,beta-lactamase_39_138,TEM-1,beta-lactamase_39,P62593,0.943733,NO,138,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.506,-4.444,1.938,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.0495842,0.00487868,0.943733 PSD95pdz3_R368C,PSD95pdz3_368,PSD95pdz3,PSD95pdz3,P31016,0.943736,NO,368,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.582,-4.769,3.187,6.13355,,,,,18.1818,,,,HBP,-1.50033,0.0758425,0.000451517,0.943736 kka2_1:4_L232Y,kka2_1:4_232,Kka2,kka2_1:4,P00552,0.943778,NO,232,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.514,-3.053,1.539,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.168804,0.00800103,0.943778 PSD95pdz3_R368A,PSD95pdz3_368,PSD95pdz3,PSD95pdz3,P31016,0.943779,NO,368,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.582,-2.759,1.177,6.13355,,,,,18.1818,,,,HBP,-1.50033,0.0758425,0.000451517,0.943779 Pab1_G163K,Pab1_163,Pab1,Pab1,P04147,0.943789,NO,163,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.809,-3.499,2.69,,0.356,B,g,,0.55,,,,POB,-1.80667,0.175299,0.00030953,0.943789 beta-lactamase_39_D113W,beta-lactamase_39_113,TEM-1,beta-lactamase_39,P62593,0.94381,NO,113,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.829,-5.545,3.716,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.0495842,0.00474112,0.94381 kka2_1:2_A176V,kka2_1:2_176,Kka2,kka2_1:2,P00552,0.943835,NO,176,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.621,-3.617,1.996,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.295029,0.0083587,0.943835 kka2_1:1_D238W,kka2_1:1_238,Kka2,kka2_1:1,P00552,0.943852,NO,238,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.83,-5.568,2.738,,0.604,H,A,0.75,-0.33,11.329,11.329,92.05,HAB,-2.633,0.520039,0.0113863,0.943852 beta-lactamase_0_L74P,beta-lactamase_0_74,TEM-1,beta-lactamase_0,P62593,0.943858,NO,74,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.296,-4.001,2.705,,,H,A,0.55,-0.91,1.46,,50,HHO,-1.34933,0.0500837,0.00493255,0.943858 beta-lactamase_0_R220K,beta-lactamase_0_220,TEM-1,beta-lactamase_0,P62593,0.943877,NO,220,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-0.942,-2.865,1.923,,0.295,I,A,1.2,-0.76,21.573,21.573,74.48,HBP,-1.33633,0.0500837,0.00232421,0.943877 beta-lactamase_F149V,beta-lactamase_149,TEM-1,beta-lactamase,P62593,0.943897,NO,149,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.299,-3.45,2.151,5.54789,0.195,H,A,1.1,0.11,1.863,,63.99,HHH,-1.46067,0.221079,0.00418462,0.943897 kka2_1:2_L152F,kka2_1:2_152,Kka2,kka2_1:2,P00552,0.943941,NO,152,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.521,-4.081,2.56,,0.547,.,A,0.55,1.36,4.526,,63.64,OHH,-1.162,0.295029,0.00674868,0.943941 Pab1_H134Y,Pab1_134,Pab1,Pab1,P04147,0.943946,NO,134,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-1.542,-3.532,1.99,,,,,,,,,,HBO,-1.346,0.175299,0.00116356,0.943946 beta-lactamase_0_D33R,beta-lactamase_0_33,TEM-1,beta-lactamase_0,P62593,0.943948,NO,33,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.321,-2.617,0.296,,0.366,H,A,0.75,0.33,12.514,12.514,77.62,BAH,-2.12133,0.0500837,0.00435556,0.943948 beta-lactamase_D269P,beta-lactamase_269,TEM-1,beta-lactamase,P62593,0.943958,NO,269,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.156,-2.765,0.609,5.47645,0.646,H,A,0.23,0.4,21.796,21.796,77.62,HAA,-1.96733,0.221079,0.00950944,0.943958 beta-lactamase_R92W,beta-lactamase_92,TEM-1,beta-lactamase,P62593,0.943958,NO,92,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.718,-5.477,3.759,5.65832,0.479,E,B,0.91,1.36,3.069,,65.38,BBH,-1.50367,0.221079,0.00429626,0.943958 kka2_1:2_L57T,kka2_1:2_57,Kka2,kka2_1:2,P00552,0.943962,NO,57,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.898,-3.729,1.831,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.295029,0.00723769,0.943962 beta-lactamase_39_L160N,beta-lactamase_39_160,TEM-1,beta-lactamase_39,P62593,0.943964,NO,160,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.977,-4.165,3.188,,0.022,,B,0.55,-0.6,0.895,,44.41,BHA,-0.936,0.0495842,0.00193775,0.943964 beta-lactamase_0_A124W,beta-lactamase_0_124,TEM-1,beta-lactamase_0,P62593,0.94398,NO,124,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.181,-5.322,4.141,,,H,A,0.46,-0.9,1.876,,64.34,HHH,-1.152,0.0500837,0.00481399,0.94398 beta-lactamase_2500_T139R,beta-lactamase_2500_139,TEM-1,beta-lactamase_2500,P62593,0.943995,NO,139,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.901,-2.238,0.337,,0.216,H,A,0.22,0.39,2.256,,77.62,PPH,-2.04667,0.361275,0.00441837,0.943995 Pab1_K164V,Pab1_164,Pab1,Pab1,P04147,0.944009,NO,164,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-2.298,-2.614,0.316,,,,,,,,,,OBP,-1.41767,0.175299,0.00255241,0.944009 beta-lactamase_0_M209S,beta-lactamase_0_209,TEM-1,beta-lactamase_0,P62593,0.94401,NO,209,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.442,-3.579,2.137,,,H,A,0.55,-0.97,3.876,,64.69,HHA,-1.52633,0.0500837,0.00625021,0.94401 kka2_1:8_R202S,kka2_1:8_202,Kka2,kka2_1:8,P00552,0.944017,NO,202,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.761,-2.977,1.216,,0.607,E,B,1.2,0.48,1.409,,52.27,OBH,-1.41067,0.100394,0.00696498,0.944017 kka2_1:8_R202S,kka2_1:8_202,Kka2,kka2_1:8,P00552,0.944017,NO,202,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.761,-2.977,1.216,,0.607,E,B,1.2,0.48,1.409,,52.27,OBH,-1.41067,0.100394,0.00696498,0.944017 beta-lactamase_0_W288V,beta-lactamase_0_288,TEM-1,beta-lactamase_0,P62593,0.944024,NO,288,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,,,,,,,,,,,,,BHO,,0.0500837,,0.944024 beta-lactamase_0_D252V,beta-lactamase_0_252,TEM-1,beta-lactamase_0,P62593,0.944043,NO,252,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.0500837,0.00575769,0.944043 WW_domain_A180A,WW_domain_180,Yap65,WW_domain,P46937,0.944063,NO,180,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.242,-1.242,0,6.02829,,,,,,0.627,,23.61,HHB,-1.37767,0.153962,0.00413929,0.944063 beta-lactamase_0_V29K,beta-lactamase_0_29,TEM-1,beta-lactamase_0,P62593,0.944078,NO,29,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-2.856,-2.195,-0.661,,0.733,H,A,0.44,-0.78,21.916,21.916,93.01,HHB,-2.24733,0.0500837,0.00318969,0.944078 beta-lactamase_625_R91F,beta-lactamase_625_91,TEM-1,beta-lactamase_625,P62593,0.944099,NO,91,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.392,-4.376,2.984,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.213352,0.00380226,0.944099 beta-lactamase_39_D48V,beta-lactamase_39_48,TEM-1,beta-lactamase_39,P62593,0.94414,NO,48,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.101,-3.719,2.618,,0.189,E,B,0.75,0.21,0.735,,50.35,HAH,-1.62467,0.0495842,0.0027273,0.94414 beta-lactamase_39_M153N,beta-lactamase_39_153,TEM-1,beta-lactamase_39,P62593,0.944167,NO,153,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-3.193,-3.994,0.801,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.0495842,0.00509109,0.944167 beta-lactamase_G251C,beta-lactamase_251,TEM-1,beta-lactamase,P62593,0.944203,NO,251,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.907,-5.181,3.274,5.33865,0.506,T,l,0.73,0.17,10.663,,65.38,AOB,-2.06067,0.221079,0.00733416,0.944203 beta-lactamase_2500_N168G,beta-lactamase_2500_168,TEM-1,beta-lactamase_2500,P62593,0.944205,NO,168,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-1.029,-3.01,1.981,,0.113,G,A,0.61,-0.4,2.9,,44.41,HPA,-1.13233,0.361275,0.00288667,0.944205 beta-lactamase_P217R,beta-lactamase_217,TEM-1,beta-lactamase,P62593,0.944218,NO,217,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-2.062,-3.069,1.007,5.19872,0.496,I,A,0.99,-0.33,0.431,,74.48,OOH,-1.64333,0.221079,0.00463211,0.944218 kka2_1:4_D118L,kka2_1:4_118,Kka2,kka2_1:4,P00552,0.944234,NO,118,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.07,-3.589,1.519,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.168804,0.0067852,0.944234 beta-lactamase_0_E166Q,beta-lactamase_0_166,TEM-1,beta-lactamase_0,P62593,0.944239,NO,166,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.756,-3.022,1.266,,0.508,G,A,1.04,1.05,17.227,17.227,73.08,OAH,-1.42233,0.0500837,0.00512989,0.944239 Pab1_M189N,Pab1_189,Pab1,Pab1,P04147,0.94425,NO,189,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.406,-3.715,2.309,,0.631,E,b,,2.81,,,,OHH,-1.18,0.175299,0.000278756,0.94425 kka2_1:4_A229N,kka2_1:4_229,Kka2,kka2_1:4,P00552,0.944255,NO,229,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.739,-3.848,2.109,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.168804,0.00942138,0.944255 beta-lactamase_S57C,beta-lactamase_57,TEM-1,beta-lactamase,P62593,0.944287,NO,57,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.918,-4.926,3.008,5.64201,0.352,E,B,0.25,-0.18,1.971,,72.73,APH,-2.29167,0.221079,0.00492804,0.944287 beta-lactamase_H5D,beta-lactamase_5,TEM-1,beta-lactamase,P62593,0.944295,NO,5,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-2.698,-3.777,1.079,,,,,,,1.865,,72.73,PBH,-2.36967,0.221079,0.00292712,0.944295 beta-lactamase_2500_R81A,beta-lactamase_2500_81,TEM-1,beta-lactamase_2500,P62593,0.944317,NO,81,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.466,-2.609,1.143,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.361275,0.00499763,0.944317 beta-lactamase_0_S96F,beta-lactamase_0_96,TEM-1,beta-lactamase_0,P62593,0.944326,NO,96,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.27,-4.388,2.118,,0.368,,b,0.27,0.39,2.516,,73.78,HPP,-2.019,0.0500837,0.00551835,0.944326 Pab1_I137L,Pab1_137,Pab1,Pab1,P04147,0.944384,NO,137,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.212,-2.275,1.063,,0.068,,B,0.77,0.35,,,,AHA,-1.314,0.175299,0.000342224,0.944384 beta-lactamase_625_S80K,beta-lactamase_625_80,TEM-1,beta-lactamase_625,P62593,0.944393,NO,80,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.029,-2.901,0.872,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.213352,0.00565569,0.944393 kka2_1:8_N58E,kka2_1:8_58,Kka2,kka2_1:8,P00552,0.944407,NO,58,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-2.641,-3.612,0.971,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.100394,0.00793425,0.944407 kka2_1:8_N58E,kka2_1:8_58,Kka2,kka2_1:8,P00552,0.944407,NO,58,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-2.641,-3.612,0.971,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.100394,0.00793425,0.944407 beta-lactamase_39_Y103I,beta-lactamase_39_103,TEM-1,beta-lactamase_39,P62593,0.944414,NO,103,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-1.33,-3.874,2.544,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.0495842,0.00443048,0.944414 beta-lactamase_2500_D113L,beta-lactamase_2500_113,TEM-1,beta-lactamase_2500,P62593,0.944422,NO,113,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.829,-3.651,1.822,,0.665,T,A,0.75,0.91,21.104,21.104,73.08,PAO,-1.703,0.361275,0.00474112,0.944422 gb1_V280F,gb1_280,gb1,gb1,P06654,0.944436,NO,280,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.764,-3.72,1.956,,,,,,,0.874,,35.71,PHP,-1.63733,0.177985,0.00321577,0.944436 beta-lactamase_625_C121L,beta-lactamase_625_121,TEM-1,beta-lactamase_625,P62593,0.944439,NO,121,C,L,CL,Special,Hydrophobic,5.07,9.7088,4.6388,198,121,131,10,108.5,166.7,58.2,-0.953,-3.182,2.229,,,H,A,0.46,-0.81,1.143,,63.29,HOP,-1.46767,0.213352,0.000744322,0.944439 beta-lactamase_39_G281I,beta-lactamase_39_281,TEM-1,beta-lactamase_39,P62593,0.944468,NO,281,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.0495842,0.0406482,0.944468 kka2_1:4_P179T,kka2_1:4_179,Kka2,kka2_1:4,P00552,0.944489,NO,179,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.974,-3.471,2.497,,0.113,,B,0.52,0.69,10.913,10.913,56.06,HOA,-2.19867,0.168804,0.00298346,0.944489 beta-lactamase_0_P181G,beta-lactamase_0_181,TEM-1,beta-lactamase_0,P62593,0.944508,NO,181,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.813,-3.321,2.508,,,H,A,0.52,-1.14,1.357,,61.54,HOH,-1.795,0.0500837,0.000703122,0.944508 beta-lactamase_D99N,beta-lactamase_99,TEM-1,beta-lactamase,P62593,0.944519,NO,99,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.191,-3.466,2.275,5.66081,0.402,G,A,0.23,0.36,1.318,,64.69,PAH,-1.794,0.221079,0.00305446,0.944519 kka2_1:8_L107W,kka2_1:8_107,Kka2,kka2_1:8,P00552,0.944523,NO,107,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.238,-5.321,4.083,,0.197,.,B,0.55,-1.1,4.478,,71.59,BHH,-2.143,0.100394,0.00561937,0.944523 kka2_1:8_L107W,kka2_1:8_107,Kka2,kka2_1:8,P00552,0.944523,NO,107,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.238,-5.321,4.083,,0.197,.,B,0.55,-1.1,4.478,,71.59,BHH,-2.143,0.100394,0.00561937,0.944523 beta-lactamase_0_V260E,beta-lactamase_0_260,TEM-1,beta-lactamase_0,P62593,0.944526,NO,260,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.0500837,0.00471757,0.944526 beta-lactamase_39_L100F,beta-lactamase_39_100,TEM-1,beta-lactamase_39,P62593,0.944568,NO,100,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.218,-3.677,2.459,,0.343,,B,0.55,0.13,8.311,,63.29,AHH,-1.23467,0.0495842,0.00413885,0.944568 Pab1_M189G,Pab1_189,Pab1,Pab1,P04147,0.944569,NO,189,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.406,-3.4,1.994,,0.631,E,b,,2.81,,,,OHH,-1.18,0.175299,0.000278756,0.944569 beta-lactamase_0_T179Q,beta-lactamase_0_179,TEM-1,beta-lactamase_0,P62593,0.944598,NO,179,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.085,-3.906,2.821,,,E,B,0.22,-1.38,0.367,,73.08,PPH,-1.557,0.0500837,0.00226045,0.944598 beta-lactamase_156_Q203N,beta-lactamase_156_203,TEM-1,beta-lactamase_156,P62593,0.944605,NO,203,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.168,-3.727,1.559,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.111618,0.00631514,0.944605 beta-lactamase_156_I93S,beta-lactamase_156_93,TEM-1,beta-lactamase_156,P62593,0.944616,NO,93,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.401,-3.663,2.262,,0.128,E,B,0.48,0.44,1.524,,67.83,BHB,-1.873,0.111618,0.00527066,0.944616 beta-lactamase_V157G,beta-lactamase_157,TEM-1,beta-lactamase,P62593,0.944616,NO,157,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.751,-3.625,1.874,5.51733,0.308,S,a,0.96,-0.75,1.847,,69.58,BHP,-2.00767,0.221079,0.00506849,0.944616 beta-lactamase_0_G240I,beta-lactamase_0_240,TEM-1,beta-lactamase_0,P62593,0.944644,NO,240,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.0500837,0.00591201,0.944644 beta-lactamase_39_E56N,beta-lactamase_39_56,TEM-1,beta-lactamase_39,P62593,0.944654,NO,56,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.043,-2.542,0.499,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.0495842,0.00238534,0.944654 beta-lactamase_2500_K213N,beta-lactamase_2500_213,TEM-1,beta-lactamase_2500,P62593,0.944658,NO,213,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.81,-3.623,1.813,,0.67,,A,2.34,0.29,1.668,,67.83,ABH,-1.57767,0.361275,0.00610411,0.944658 kka2_1:1_Q4R,kka2_1:1_4,Kka2,kka2_1:1,P00552,0.944689,NO,4,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.361,-3.443,1.082,,,,,,,5.615,,71.59,APA,-1.95533,0.520039,0.00239179,0.944689 beta-lactamase_2500_Q204S,beta-lactamase_2500_204,TEM-1,beta-lactamase_2500,P62593,0.944702,NO,204,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-1.382,-3.344,1.962,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.361275,0.00364106,0.944702 beta-lactamase_0_N134C,beta-lactamase_0_134,TEM-1,beta-lactamase_0,P62593,0.94472,NO,134,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-0.879,-5.113,4.234,,0.138,H,A,0.61,-0.6,3.776,,53.15,HPH,-1.02233,0.0500837,0.000644786,0.94472 beta-lactamase_2500_G85M,beta-lactamase_2500_85,TEM-1,beta-lactamase_2500,P62593,0.944749,NO,85,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.011,-4.877,3.866,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.361275,0.00252173,0.944749 kka2_1:8_R122C,kka2_1:8_122,Kka2,kka2_1:8,P00552,0.944757,NO,122,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.175,-5.179,3.004,,0.487,H,A,1.2,0.26,22.675,22.675,71.59,BBH,-1.53833,0.100394,0.00736512,0.944757 kka2_1:8_R122C,kka2_1:8_122,Kka2,kka2_1:8,P00552,0.944757,NO,122,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.175,-5.179,3.004,,0.487,H,A,1.2,0.26,22.675,22.675,71.59,BBH,-1.53833,0.100394,0.00736512,0.944757 beta-lactamase_2500_R81M,beta-lactamase_2500_81,TEM-1,beta-lactamase_2500,P62593,0.944787,NO,81,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.466,-4.579,3.113,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.361275,0.00499763,0.944787 kka2_1:1_G234W,kka2_1:1_234,Kka2,kka2_1:1,P00552,0.944826,NO,234,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-2.9,-5.618,2.718,,0.494,H,A,0.29,-0.29,1.753,,71.59,OOA,-1.86767,0.520039,0.00984449,0.944826 beta-lactamase_K109W,beta-lactamase_109,TEM-1,beta-lactamase,P62593,0.944863,NO,109,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.734,-5.518,3.784,6.05842,0.787,G,A,1.82,2.21,21.623,21.623,72.73,ABB,-1.63333,0.221079,0.00462493,0.944863 beta-lactamase_M127I,beta-lactamase_127,TEM-1,beta-lactamase,P62593,0.944863,NO,127,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-2.251,-2.439,0.188,5.40552,0.312,S,A,1.07,0.32,1.671,,72.73,PHP,-1.40433,0.221079,0.00437927,0.944863 beta-lactamase_R59N,beta-lactamase_59,TEM-1,beta-lactamase,P62593,0.944863,NO,59,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.345,-2.533,1.188,5.49837,0.329,S,L,0.68,-0.09,1.806,,73.08,HBO,-2.24267,0.221079,0.00318082,0.944863 beta-lactamase_S254W,beta-lactamase_254,TEM-1,beta-lactamase,P62593,0.944863,NO,254,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.126,-5.534,3.408,5.49575,0.312,,a,0.25,-0.48,24.91,24.91,69.58,OPB,-2.215,0.221079,0.00369,0.944863 beta-lactamase_X287F,beta-lactamase_287,TEM-1,beta-lactamase,P62593,0.944863,NO,287,X,F,XF,Stop,Hydrophobic,5.71,3.32051,-2.38949,,132.5,165,32,141.9,189.9,48,,,,,,,,,,,,,HXO,-1.111,0.221079,,0.944863 kka2_1:8_T225R,kka2_1:8_225,Kka2,kka2_1:8,P00552,0.944893,NO,225,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.393,-4.06,1.667,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.100394,0.0113598,0.944893 kka2_1:8_T225R,kka2_1:8_225,Kka2,kka2_1:8,P00552,0.944893,NO,225,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.393,-4.06,1.667,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.100394,0.0113598,0.944893 beta-lactamase_2500_A84F,beta-lactamase_2500_84,TEM-1,beta-lactamase_2500,P62593,0.94491,NO,84,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.651,-4.366,2.715,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.361275,0.00503822,0.94491 Pab1_T159F,Pab1_159,Pab1,Pab1,P04147,0.944921,NO,159,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.445,-3.958,2.513,,,,,,,2.531,,79.03,HPA,-1.19467,0.175299,0.00133849,0.944921 beta-lactamase_39_D271W,beta-lactamase_39_271,TEM-1,beta-lactamase_39,P62593,0.944949,NO,271,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.0495842,0.00752082,0.944949 beta-lactamase_39_D212P,beta-lactamase_39_212,TEM-1,beta-lactamase_39,P62593,0.944966,NO,212,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.624,-3.916,2.292,,0.037,,b,0.75,-0.58,10.748,10.748,74.48,HAB,-1.77667,0.0495842,0.00644302,0.944966 beta-lactamase_156_A268F,beta-lactamase_156_268,TEM-1,beta-lactamase_156,P62593,0.94497,NO,268,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.111618,0.0102525,0.94497 kka2_1:8_Q61G,kka2_1:8_61,Kka2,kka2_1:8,P00552,0.944971,NO,61,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.982,-2.486,-0.496,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.100394,0.00612092,0.944971 kka2_1:8_Q61G,kka2_1:8_61,Kka2,kka2_1:8,P00552,0.944971,NO,61,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.982,-2.486,-0.496,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.100394,0.00612092,0.944971 beta-lactamase_2500_E145L,beta-lactamase_2500_145,TEM-1,beta-lactamase_2500,P62593,0.944975,NO,145,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.357,-3.644,1.287,,0.545,H,A,1.04,0.79,2.124,,77.62,BAH,-2.069,0.361275,0.00553285,0.944975 WW_domain_M179R,WW_domain_179,Yap65,WW_domain,P46937,0.945005,NO,179,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.541,-3.485,1.944,6.54704,,,,,,,,,AHH,-1.31367,0.153962,0.00400164,0.945005 beta-lactamase_39_M115L,beta-lactamase_39_115,TEM-1,beta-lactamase_39,P62593,0.94501,NO,115,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.389,-1.859,0.47,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.0495842,0.0034337,0.94501 Pab1_L153W,Pab1_153,Pab1,Pab1,P04147,0.94502,NO,153,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.039,-4.915,3.876,,0.46,E,A,,-0.95,,,,HHP,-1.17667,0.175299,0.000321212,0.94502 beta-lactamase_2500_E108Y,beta-lactamase_2500_108,TEM-1,beta-lactamase_2500,P62593,0.945061,NO,108,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.46,-4.347,2.887,,0.572,G,A,1.04,1.87,1.147,,72.73,PAB,-1.437,0.361275,0.00413372,0.945061 beta-lactamase_39_A211S,beta-lactamase_39_211,TEM-1,beta-lactamase_39,P62593,0.945086,NO,211,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.896,-2.788,0.892,,0.369,T,A,0.46,-0.69,1.419,,77.62,AHA,-1.94633,0.0495842,0.00648183,0.945086 beta-lactamase_0_L74E,beta-lactamase_0_74,TEM-1,beta-lactamase_0,P62593,0.945094,NO,74,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.296,-3.786,2.49,,,H,A,0.55,-0.91,1.46,,50,HHO,-1.34933,0.0500837,0.00493255,0.945094 beta-lactamase_0_F64K,beta-lactamase_0_64,TEM-1,beta-lactamase_0,P62593,0.945112,NO,64,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-0.841,-3.907,3.066,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.0500837,0.000947691,0.945112 beta-lactamase_R176H,beta-lactamase_176,TEM-1,beta-lactamase,P62593,0.945115,NO,176,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-0.863,-4.23,3.367,5.61264,0.385,T,B,0.68,-0.63,,,,ABA,-1.38867,0.221079,0.00105554,0.945115 beta-lactamase_0_K32A,beta-lactamase_0_32,TEM-1,beta-lactamase_0,P62593,0.945123,NO,32,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.984,-2.363,0.379,,0.563,H,A,2.34,0.34,0.418,,73.08,HBA,-2.04233,0.0500837,0.00401283,0.945123 kka2_1:4_P12K,kka2_1:4_12,Kka2,kka2_1:4,P00552,0.945129,NO,12,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.853,-3.495,2.642,,,,B,0.52,1.25,0.843,,48.11,POH,-1.80767,0.168804,0.00500011,0.945129 Pab1_I183Y,Pab1_183,Pab1,Pab1,P04147,0.945136,NO,183,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.302,-3.808,2.506,,0.308,T,B,1,1.08,1.29,,75.56,HHA,-1.27167,0.175299,0.000574345,0.945136 kka2_1:4_E230W,kka2_1:4_230,Kka2,kka2_1:4,P00552,0.945161,NO,230,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.672,-5.201,2.529,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.168804,0.00920051,0.945161 PSD95pdz3_V362M,PSD95pdz3_362,PSD95pdz3,PSD95pdz3,P31016,0.945187,NO,362,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.465,-3.712,2.247,4.99436,,,,,19.6443,,,,PHP,-1.46467,0.0758425,0.000538527,0.945187 Pab1_N192L,Pab1_192,Pab1,Pab1,P04147,0.945199,NO,192,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-1.079,-3.4,2.321,,0.619,T,l,,2.28,,,,HPO,-1.231,0.175299,0.000273498,0.945199 beta-lactamase_2500_T264Y,beta-lactamase_2500_264,TEM-1,beta-lactamase_2500,P62593,0.945207,NO,264,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.361275,0.0119399,0.945207 beta-lactamase_D250I,beta-lactamase_250,TEM-1,beta-lactamase,P62593,0.945257,NO,250,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.335,-3.184,0.849,5.72026,0.89,T,L,0.23,1.53,24.737,24.737,66.08,OAO,-1.85133,0.221079,0.00550899,0.945257 kka2_1:4_P179Q,kka2_1:4_179,Kka2,kka2_1:4,P00552,0.945257,NO,179,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.974,-4.023,3.049,,0.113,,B,0.52,0.69,10.913,10.913,56.06,HOA,-2.19867,0.168804,0.00298346,0.945257 beta-lactamase_G234A,beta-lactamase_234,TEM-1,beta-lactamase,P62593,0.945264,NO,234,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.62,-2.853,2.233,4.24221,0.023,E,B,0.46,-0.86,,,,POH,-1.25733,0.221079,0.000889577,0.945264 beta-lactamase_P249R,beta-lactamase_249,TEM-1,beta-lactamase,P62593,0.945275,NO,249,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.312,-2.999,1.687,5.10655,0.256,S,B,0.99,0.04,0.479,,72.73,OOA,-1.81367,0.221079,0.00220169,0.945275 PSD95pdz3_L367Q,PSD95pdz3_367,PSD95pdz3,PSD95pdz3,P31016,0.945293,NO,367,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.347,-3.806,2.459,5.47696,,,,,17.0063,,,,AHB,-1.39767,0.0758425,0.000466436,0.945293 Pab1_F168H,Pab1_168,Pab1,Pab1,P04147,0.945302,NO,168,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.269,-4.114,2.845,,,,,,,0.789,,56.33,OHO,-1.10033,0.175299,0.00064061,0.945302 kka2_1:4_E169Y,kka2_1:4_169,Kka2,kka2_1:4,P00552,0.945307,NO,169,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.996,-4.385,2.389,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.168804,0.00730086,0.945307 kka2_1:2_D101A,kka2_1:2_101,Kka2,kka2_1:2,P00552,0.945308,NO,101,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.028,-2.654,1.626,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.295029,0.00423361,0.945308 Pab1_L142I,Pab1_142,Pab1,Pab1,P04147,0.945333,NO,142,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.039,-2.702,1.663,,0.007,H,A,0.84,-0.65,,,,HHH,-1.487,0.175299,0.000335477,0.945333 beta-lactamase_S122T,beta-lactamase_122,TEM-1,beta-lactamase,P62593,0.945362,NO,122,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.406,-2.952,0.546,4.87767,0.352,H,A,0.73,-0.54,1.581,,77.62,OPH,-1.39767,0.221079,0.00497825,0.945362 beta-lactamase_2500_T264A,beta-lactamase_2500_264,TEM-1,beta-lactamase_2500,P62593,0.945366,NO,264,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.361275,0.0119399,0.945366 beta-lactamase_39_D252M,beta-lactamase_39_252,TEM-1,beta-lactamase_39,P62593,0.945367,NO,252,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.0495842,0.00575769,0.945367 PSD95pdz3_S350Y,PSD95pdz3_350,PSD95pdz3,PSD95pdz3,P31016,0.945384,NO,350,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.519,-3.844,2.325,4.97629,,,,,25.01,,,,HPO,-1.29133,0.0758425,0.000704883,0.945384 PSD95pdz3_A382V,PSD95pdz3_382,PSD95pdz3,PSD95pdz3,P31016,0.945389,NO,382,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.307,-2.76,1.453,5.30282,,,,,22.472,,,,PHO,-1.24167,0.0758425,0.000249256,0.945389 kka2_1:2_P76G,kka2_1:2_76,Kka2,kka2_1:2,P00552,0.945404,NO,76,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.449,-3.458,2.009,,0.331,.,B,0.52,-0.41,0.345,,63.64,HOO,-1.662,0.295029,0.00625685,0.945404 Pab1_D184I,Pab1_184,Pab1,Pab1,P04147,0.945404,NO,184,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.5,-3.899,2.399,,,,,,,,,,HAH,-1.50133,0.175299,0.0011931,0.945404 beta-lactamase_S80C,beta-lactamase_80,TEM-1,beta-lactamase,P62593,0.945406,NO,80,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.029,-4.922,2.893,5.23748,0.192,H,A,0.25,0.46,2.256,,77.62,HPB,-1.44567,0.221079,0.00565569,0.945406 beta-lactamase_2500_I140F,beta-lactamase_2500_140,TEM-1,beta-lactamase_2500,P62593,0.945422,NO,140,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.733,-2.91,1.177,,0.128,H,A,0.48,0.41,1.628,,73.08,PHO,-1.48733,0.361275,0.00597777,0.945422 Pab1_K164Y,Pab1_164,Pab1,Pab1,P04147,0.945433,NO,164,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-2.298,-4.026,1.728,,,,,,,,,,OBP,-1.41767,0.175299,0.00255241,0.945433 kka2_1:8_G164A,kka2_1:8_164,Kka2,kka2_1:8,P00552,0.945436,NO,164,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.869,-3.006,2.137,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.100394,0.00442091,0.945436 kka2_1:8_G164A,kka2_1:8_164,Kka2,kka2_1:8,P00552,0.945436,NO,164,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.869,-3.006,2.137,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.100394,0.00442091,0.945436 beta-lactamase_0_L199W,beta-lactamase_0_199,TEM-1,beta-lactamase_0,P62593,0.945457,NO,199,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-2.942,-5.582,2.64,,0.832,H,A,0.55,0.42,10.85,10.85,77.62,PHH,-2.32933,0.0500837,0.0048649,0.945457 beta-lactamase_E108A,beta-lactamase_108,TEM-1,beta-lactamase,P62593,0.945459,NO,108,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.46,-2.613,1.153,5.52079,0.572,G,A,0.52,1.87,1.973,,72.73,PAB,-1.437,0.221079,0.00413372,0.945459 kka2_1:8_W15T,kka2_1:8_15,Kka2,kka2_1:8,P00552,0.945475,NO,15,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-1.392,-3.666,2.274,,0.01,G,A,1.51,0.15,0.827,,52.27,HHH,-2.10533,0.100394,0.00585505,0.945475 kka2_1:8_W15T,kka2_1:8_15,Kka2,kka2_1:8,P00552,0.945475,NO,15,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-1.392,-3.666,2.274,,0.01,G,A,1.51,0.15,0.827,,52.27,HHH,-2.10533,0.100394,0.00585505,0.945475 beta-lactamase_2500_D207F,beta-lactamase_2500_207,TEM-1,beta-lactamase_2500,P62593,0.945508,NO,207,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.064,-4.437,2.373,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.361275,0.00592942,0.945508 beta-lactamase_0_V260Y,beta-lactamase_0_260,TEM-1,beta-lactamase_0,P62593,0.945518,NO,260,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.101,-3.316,2.215,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.0500837,0.00471757,0.945518 beta-lactamase_K144H,beta-lactamase_144,TEM-1,beta-lactamase,P62593,0.945524,NO,144,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-2.388,-3.395,1.007,6.02507,0.863,H,A,2.81,1.27,0.515,,77.62,OBA,-1.904,0.221079,0.00481141,0.945524 beta-lactamase_0_E145P,beta-lactamase_0_145,TEM-1,beta-lactamase_0,P62593,0.945551,NO,145,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.357,-3.914,1.557,,0.545,H,A,1.04,0.79,1.199,,77.62,BAH,-2.069,0.0500837,0.00553285,0.945551 gb1_K236M,gb1_236,gb1,gb1,P06654,0.945568,NO,236,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-2.119,-4.379,2.26,,,,,,,1.083,,45.54,OBP,-1.758,0.177985,0.00255408,0.945568 Pab1_S147W,Pab1_147,Pab1,Pab1,P04147,0.945603,NO,147,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.267,-5.133,3.866,,0.336,H,A,,0.56,,,,HPH,-1.43033,0.175299,0.000610856,0.945603 beta-lactamase_D99V,beta-lactamase_99,TEM-1,beta-lactamase,P62593,0.945619,NO,99,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.191,-3.648,2.457,5.66081,0.402,G,A,0.23,0.36,1.318,,64.69,PAH,-1.794,0.221079,0.00305446,0.945619 beta-lactamase_2500_D207I,beta-lactamase_2500_207,TEM-1,beta-lactamase_2500,P62593,0.945623,NO,207,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.064,-4.165,2.101,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.361275,0.00592942,0.945623 beta-lactamase_0_Q97V,beta-lactamase_0_97,TEM-1,beta-lactamase_0,P62593,0.945695,NO,97,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.072,-3.633,1.561,,0.823,G,A,0.64,2.42,16.954,16.954,77.62,PPP,-2.43833,0.0500837,0.0045116,0.945695 beta-lactamase_0_S96L,beta-lactamase_0_96,TEM-1,beta-lactamase_0,P62593,0.945702,NO,96,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.27,-3.527,1.257,,0.368,,b,0.27,0.39,2.516,,73.78,HPP,-2.019,0.0500837,0.00551835,0.945702 beta-lactamase_T262I,beta-lactamase_262,TEM-1,beta-lactamase,P62593,0.945706,NO,262,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.332,-3.789,2.457,5.06002,0.108,E,B,0.3,-0.55,1.423,,67.83,PPO,-2.081,0.221079,0.00853516,0.945706 kka2_1:4_K138C,kka2_1:4_138,Kka2,kka2_1:4,P00552,0.945725,NO,138,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-2.5,-5.226,2.726,,0.594,H,A,1.3,0.98,21.267,21.267,71.59,HBB,-2.48833,0.168804,0.00628542,0.945725 beta-lactamase_39_P165I,beta-lactamase_39_165,TEM-1,beta-lactamase_39,P62593,0.94573,NO,165,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.373,-3.815,2.442,,0.203,T,A,0.52,-0.31,3.907,,73.78,AOA,-1.359,0.0495842,0.00549538,0.94573 beta-lactamase_39_I206N,beta-lactamase_39_206,TEM-1,beta-lactamase_39,P62593,0.945748,NO,206,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-2.429,-3.933,1.504,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.0495842,0.00528934,0.945748 beta-lactamase_625_E108K,beta-lactamase_625_108,TEM-1,beta-lactamase_625,P62593,0.945755,NO,108,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.46,-2.182,0.722,,0.572,G,A,1.04,1.87,20.151,20.151,72.73,PAB,-1.437,0.213352,0.00413372,0.945755 beta-lactamase_39_R257E,beta-lactamase_39_257,TEM-1,beta-lactamase_39,P62593,0.945756,NO,257,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.0495842,0.00756629,0.945756 kka2_1:2_C31S,kka2_1:2_31,Kka2,kka2_1:2,P00552,0.945761,NO,31,C,S,CS,Special,Polar,5.07,5.68,0.61,112,121,105,-16,108.5,89,-19.5,-2.246,-3.485,1.239,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.295029,0.00681582,0.945761 beta-lactamase_P217V,beta-lactamase_217,TEM-1,beta-lactamase,P62593,0.945768,NO,217,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-2.062,-3.65,1.588,5.19872,0.496,I,A,0.99,-0.33,0.431,,74.48,OOH,-1.64333,0.221079,0.00463211,0.945768 beta-lactamase_0_R202E,beta-lactamase_0_202,TEM-1,beta-lactamase_0,P62593,0.94577,NO,202,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.292,-3.173,1.881,,0.188,H,A,1.2,0.62,7.016,,77.62,PBP,-1.54767,0.0500837,0.00321899,0.94577 beta-lactamase_0_L111T,beta-lactamase_0_111,TEM-1,beta-lactamase_0,P62593,0.945787,NO,111,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.76,-2.765,1.005,,0.328,T,A,0.55,0.93,1.966,,64.34,BHP,-1.884,0.0500837,0.00480671,0.945787 beta-lactamase_V214T,beta-lactamase_214,TEM-1,beta-lactamase,P62593,0.945791,NO,214,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.299,-1.73,0.431,5.74008,0.375,S,A,1.19,-0.44,1.899,,74.48,BHH,-1.53733,0.221079,0.00628442,0.945791 PSD95pdz3_G345L,PSD95pdz3_345,PSD95pdz3,PSD95pdz3,P31016,0.94582,NO,345,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.008,-3.49,2.482,4.32868,,,,,13.165,,,,OOO,-1.084,0.0758425,0.000771806,0.94582 beta-lactamase_A183N,beta-lactamase_183,TEM-1,beta-lactamase,P62593,0.945841,NO,183,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.231,-2.504,1.273,4.84712,0.155,H,A,0.55,-0.91,12.189,,77.62,HHH,-1.53367,0.221079,0.00296631,0.945841 beta-lactamase_T262M,beta-lactamase_262,TEM-1,beta-lactamase,P62593,0.945841,NO,262,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.332,-4.602,3.27,5.06002,0.108,E,B,0.3,-0.55,1.423,,67.83,PPO,-2.081,0.221079,0.00853516,0.945841 beta-lactamase_2500_E145W,beta-lactamase_2500_145,TEM-1,beta-lactamase_2500,P62593,0.945867,NO,145,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.357,-5.352,2.995,,0.545,H,A,1.04,0.79,2.124,,77.62,BAH,-2.069,0.361275,0.00553285,0.945867 WW_domain_W177W,WW_domain_177,Yap65,WW_domain,P46937,0.945871,NO,177,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-1.198,-1.198,0,5.18137,,,,,,,,,OHA,-1.197,0.153962,0.00198549,0.945871 beta-lactamase_0_P65W,beta-lactamase_0_65,TEM-1,beta-lactamase_0,P62593,0.945884,NO,65,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.894,-5.47,4.576,,0.098,E,B,0.52,-0.62,0.663,,40.56,HOH,-1.03233,0.0500837,0.00152776,0.945884 PSD95pdz3_T385E,PSD95pdz3_385,PSD95pdz3,PSD95pdz3,P31016,0.945917,NO,385,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.533,-3.121,1.588,5.57157,,,,,23.6871,4.527,,87.71,PPH,-1.56567,0.0758425,0.000545119,0.945917 kka2_1:8_P109C,kka2_1:8_109,Kka2,kka2_1:8,P00552,0.945921,NO,109,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.412,-5.056,3.644,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.100394,0.0070929,0.945921 kka2_1:8_P109C,kka2_1:8_109,Kka2,kka2_1:8,P00552,0.945921,NO,109,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.412,-5.056,3.644,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.100394,0.0070929,0.945921 beta-lactamase_R91H,beta-lactamase_91,TEM-1,beta-lactamase,P62593,0.945926,NO,91,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.392,-4.422,3.03,5.92536,0.444,,B,0.68,0.96,1.318,,50.35,OBB,-1.73367,0.221079,0.00380226,0.945926 beta-lactamase_156_A40N,beta-lactamase_156_40,TEM-1,beta-lactamase_156,P62593,0.94595,NO,40,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.402,-3.756,2.354,,0.155,S,B,0.46,0.21,1.357,,73.78,OHB,-1.40267,0.111618,0.00490026,0.94595 beta-lactamase_0_L192W,beta-lactamase_0_192,TEM-1,beta-lactamase_0,P62593,0.945956,NO,192,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.254,-5.176,3.922,,0.095,H,A,0.55,0.35,1.756,,60.14,HHP,-1.41833,0.0500837,0.00558728,0.945956 beta-lactamase_625_G52T,beta-lactamase_625_52,TEM-1,beta-lactamase_625,P62593,0.945956,NO,52,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.149,-3.586,2.437,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.213352,0.00340138,0.945956 kka2_1:8_G21V,kka2_1:8_21,Kka2,kka2_1:8,P00552,0.94596,NO,21,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.368,-3.817,2.449,,0.586,T,l,0.29,-0.75,4.889,,71.59,HOH,-2.10167,0.100394,0.00709648,0.94596 kka2_1:8_G21V,kka2_1:8_21,Kka2,kka2_1:8,P00552,0.94596,NO,21,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.368,-3.817,2.449,,0.586,T,l,0.29,-0.75,4.889,,71.59,HOH,-2.10167,0.100394,0.00709648,0.94596 beta-lactamase_39_D113H,beta-lactamase_39_113,TEM-1,beta-lactamase_39,P62593,0.945965,NO,113,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.829,-4.704,2.875,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.0495842,0.00474112,0.945965 Pab1_L153R,Pab1_153,Pab1,Pab1,P04147,0.945975,NO,153,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.039,-3.75,2.711,,0.46,E,A,,-0.95,,,,HHP,-1.17667,0.175299,0.000321212,0.945975 kka2_1:8_S40I,kka2_1:8_40,Kka2,kka2_1:8,P00552,0.945979,NO,40,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.645,-4.1,1.455,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.100394,0.00693477,0.945979 kka2_1:8_S40I,kka2_1:8_40,Kka2,kka2_1:8,P00552,0.945979,NO,40,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.645,-4.1,1.455,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.100394,0.00693477,0.945979 beta-lactamase_39_M180G,beta-lactamase_39_180,TEM-1,beta-lactamase_39,P62593,0.946011,NO,180,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-2.795,-3.389,0.594,,0.242,,B,0.55,-0.94,3.579,,77.62,PHO,-1.56433,0.0495842,0.00552048,0.946011 PSD95pdz3_S361D,PSD95pdz3_361,PSD95pdz3,PSD95pdz3,P31016,0.946026,NO,361,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.519,-2.925,1.406,4.8722,,,,,16.4533,,,,HPH,-1.47167,0.0758425,0.00055296,0.946026 beta-lactamase_I54C,beta-lactamase_54,TEM-1,beta-lactamase,P62593,0.946027,NO,54,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-2.838,-5.056,2.218,5.40541,0.669,E,B,0.77,-0.14,3.946,,73.78,BHH,-2.337,0.221079,0.00403589,0.946027 beta-lactamase_K32G,beta-lactamase_32,TEM-1,beta-lactamase,P62593,0.946027,NO,32,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.984,-3.506,1.522,5.55842,0.563,H,A,1.82,0.34,1.754,,73.08,HBA,-2.04233,0.221079,0.00401283,0.946027 beta-lactamase_R202E,beta-lactamase_202,TEM-1,beta-lactamase,P62593,0.946027,NO,202,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.292,-3.173,1.881,5.16273,0.188,H,A,0.68,0.62,1.918,,77.62,PBP,-1.54767,0.221079,0.00321899,0.946027 beta-lactamase_39_E35F,beta-lactamase_39_35,TEM-1,beta-lactamase_39,P62593,0.946035,NO,35,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-0.869,-4.318,3.449,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.0495842,0.00174441,0.946035 WW_domain_I193C,WW_domain_193,Yap65,WW_domain,P46937,0.946072,NO,193,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.993,-4.812,2.819,6.15906,,,,,,1.833,,83.33,BHA,-1.756,0.153962,0.00587613,0.946072 beta-lactamase_0_A235F,beta-lactamase_0_235,TEM-1,beta-lactamase_0,P62593,0.946084,NO,235,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.266,-4.199,2.933,,0.32,E,B,0.46,-0.86,2.261,,50,OHO,-0.89,0.0500837,0.00493474,0.946084 beta-lactamase_156_P224I,beta-lactamase_156_224,TEM-1,beta-lactamase_156,P62593,0.946089,NO,224,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.893,-4.034,3.141,,0.383,,B,0.52,-0.3,0.383,,74.48,HOH,-1.26433,0.111618,0.00189564,0.946089 kka2_1:8_S114D,kka2_1:8_114,Kka2,kka2_1:8,P00552,0.946134,NO,114,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.527,-2.691,0.164,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.100394,0.00705262,0.946134 kka2_1:8_S114D,kka2_1:8_114,Kka2,kka2_1:8,P00552,0.946134,NO,114,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.527,-2.691,0.164,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.100394,0.00705262,0.946134 beta-lactamase_2500_G253Y,beta-lactamase_2500_253,TEM-1,beta-lactamase_2500,P62593,0.946156,NO,253,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.361275,0.00786358,0.946156 WW_domain_S184I,WW_domain_184,Yap65,WW_domain,P46937,0.94616,NO,184,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.363,-3.556,2.193,5.06696,,,,,,,,,PPO,-1.39133,0.153962,0.00231095,0.94616 beta-lactamase_39_M180I,beta-lactamase_39_180,TEM-1,beta-lactamase_39,P62593,0.946161,NO,180,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-2.795,-3.664,0.869,,0.242,,B,0.55,-0.94,3.579,,77.62,PHO,-1.56433,0.0495842,0.00552048,0.946161 kka2_1:4_A110S,kka2_1:4_110,Kka2,kka2_1:4,P00552,0.946175,NO,110,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.064,-2.748,0.684,,0.175,H,A,0.46,-1.19,23.237,23.237,71.59,OHA,-1.91867,0.168804,0.00759851,0.946175 PSD95pdz3_R318T,PSD95pdz3_318,PSD95pdz3,PSD95pdz3,P31016,0.946179,NO,318,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.582,-3.103,1.521,4.94876,,,,,17.5609,,,,BBO,-1.40567,0.0758425,0.00110471,0.946179 beta-lactamase_2500_K213I,beta-lactamase_2500_213,TEM-1,beta-lactamase_2500,P62593,0.946192,NO,213,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.81,-4.142,2.332,,0.67,,A,2.34,0.29,1.668,,67.83,ABH,-1.57767,0.361275,0.00610411,0.946192 kka2_1:2_W69G,kka2_1:2_69,Kka2,kka2_1:2,P00552,0.946199,NO,69,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-0.859,-3.43,2.571,,0.164,H,A,0.47,0.15,5.074,,38.64,PHH,-1.49967,0.295029,0.0012874,0.946199 beta-lactamase_0_W208M,beta-lactamase_0_208,TEM-1,beta-lactamase_0,P62593,0.946239,NO,208,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-0.818,-4.48,3.662,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.0500837,0.00126609,0.946239 gb1_T243E,gb1_243,gb1,gb1,P06654,0.946244,NO,243,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.415,-3.251,1.836,,,,,,,1.083,,37.28,PPP,-1.43233,0.177985,0.00308687,0.946244 beta-lactamase_2500_H24D,beta-lactamase_2500_24,TEM-1,beta-lactamase_2500,P62593,0.946253,NO,24,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-2.481,-2.42,-0.061,,,,,,,0.467,,93.01,OBO,-2.0035,0.361275,0.00238894,0.946253 kka2_1:1_I254L,kka2_1:1_254,Kka2,kka2_1:1,P00552,0.946266,NO,254,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.933,-1.561,-0.372,,0.135,H,A,1.52,-0.6,1.859,,71.59,BHH,-1.668,0.520039,0.0132375,0.946266 beta-lactamase_0_K213Q,beta-lactamase_0_213,TEM-1,beta-lactamase_0,P62593,0.94627,NO,213,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.81,-2.028,0.218,,0.67,,A,2.34,0.29,3.015,,67.83,ABH,-1.57767,0.0500837,0.00610411,0.94627 kka2_1:1_D238A,kka2_1:1_238,Kka2,kka2_1:1,P00552,0.946286,NO,238,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.83,-1.842,-0.988,,0.604,H,A,0.75,-0.33,11.329,11.329,92.05,HAB,-2.633,0.520039,0.0113863,0.946286 kka2_1:2_T225A,kka2_1:2_225,Kka2,kka2_1:2,P00552,0.946286,NO,225,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.393,-1.787,-0.606,,0.036,H,A,0.22,-1.22,4.554,,63.64,HPB,-1.58733,0.295029,0.0113598,0.946286 beta-lactamase_39_D33R,beta-lactamase_39_33,TEM-1,beta-lactamase_39,P62593,0.946295,NO,33,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.321,-2.617,0.296,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.0495842,0.00435556,0.946295 beta-lactamase_D207H,beta-lactamase_207,TEM-1,beta-lactamase,P62593,0.9463,NO,207,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.064,-3.07,1.006,5.40404,0.409,H,A,0.23,0.12,1.975,,77.62,HAH,-1.77033,0.221079,0.00592942,0.9463 beta-lactamase_P217G,beta-lactamase_217,TEM-1,beta-lactamase,P62593,0.9463,NO,217,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-2.062,-2.748,0.686,5.19872,0.496,I,A,0.99,-0.33,0.431,,74.48,OOH,-1.64333,0.221079,0.00463211,0.9463 beta-lactamase_T139H,beta-lactamase_139,TEM-1,beta-lactamase,P62593,0.9463,NO,139,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.901,-3.291,1.39,5.69095,0.216,H,A,0.3,0.39,2.256,,77.62,PPH,-2.04667,0.221079,0.00441837,0.9463 beta-lactamase_39_D48S,beta-lactamase_39_48,TEM-1,beta-lactamase_39,P62593,0.94633,NO,48,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.101,-3.25,2.149,,0.189,E,B,0.75,0.21,0.735,,50.35,HAH,-1.62467,0.0495842,0.0027273,0.94633 PSD95pdz3_G322D,PSD95pdz3_322,PSD95pdz3,PSD95pdz3,P31016,0.946335,NO,322,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.008,-3.15,2.142,5.24791,,,,,16.3275,,,,POH,-1.24867,0.0758425,0.00105821,0.946335 beta-lactamase_39_Q203T,beta-lactamase_39_203,TEM-1,beta-lactamase_39,P62593,0.94634,NO,203,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.168,-2.523,0.355,,0.47,H,A,0.64,-0.38,1.453,,65.38,BPP,-1.614,0.0495842,0.00631514,0.94634 kka2_1:4_D134V,kka2_1:4_134,Kka2,kka2_1:4,P00552,0.946349,NO,134,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.969,-3.724,2.755,,0.421,B,B,0.75,0.31,0.733,,49.62,HAB,-1.057,0.168804,0.00270812,0.946349 kka2_1:1_H106N,kka2_1:1_106,Kka2,kka2_1:1,P00552,0.946356,NO,106,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-3.13,-3.028,-0.102,,1.065,.,a,0.17,-0.95,2.53,,71.59,PBH,-2.10433,0.520039,0.00730778,0.946356 beta-lactamase_156_E35K,beta-lactamase_156_35,TEM-1,beta-lactamase_156,P62593,0.946368,NO,35,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-0.869,-3.075,2.206,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.111618,0.00174441,0.946368 beta-lactamase_39_L284W,beta-lactamase_39_284,TEM-1,beta-lactamase_39,P62593,0.946408,NO,284,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.0495842,0.0686156,0.946408 kka2_1:4_P179Y,kka2_1:4_179,Kka2,kka2_1:4,P00552,0.946408,NO,179,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.974,-4.379,3.405,,0.113,,B,0.52,0.69,10.913,10.913,56.06,HOA,-2.19867,0.168804,0.00298346,0.946408 beta-lactamase_2500_H110A,beta-lactamase_2500_110,TEM-1,beta-lactamase_2500,P62593,0.946463,NO,110,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-1.706,-3.353,1.647,,0.341,G,a,0.17,1.08,31.31,31.31,64.69,BBH,-1.73333,0.361275,0.00441499,0.946463 beta-lactamase_39_A170C,beta-lactamase_39_170,TEM-1,beta-lactamase_39,P62593,0.94647,NO,170,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.237,-4.736,3.499,,0.126,,L,0.46,-0.35,3.7,,64.69,AHH,-1.63267,0.0495842,0.00431903,0.94647 kka2_1:8_A224M,kka2_1:8_224,Kka2,kka2_1:8,P00552,0.94654,NO,224,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.977,-4.55,3.573,,,H,A,0.46,-1.26,0.357,,63.64,HHP,-1.41033,0.100394,0.00352047,0.94654 kka2_1:8_A224M,kka2_1:8_224,Kka2,kka2_1:8,P00552,0.94654,NO,224,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.977,-4.55,3.573,,,H,A,0.46,-1.26,0.357,,63.64,HHP,-1.41033,0.100394,0.00352047,0.94654 beta-lactamase_0_V78W,beta-lactamase_0_78,TEM-1,beta-lactamase_0,P62593,0.946566,NO,78,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.459,-5.345,3.886,,,H,A,0.44,-0.47,16.615,16.615,63.64,HHH,-1.17833,0.0500837,0.00492501,0.946566 beta-lactamase_39_M127D,beta-lactamase_39_127,TEM-1,beta-lactamase_39,P62593,0.946576,NO,127,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-2.251,-3.966,1.715,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.0495842,0.00437927,0.946576 beta-lactamase_2500_T126C,beta-lactamase_2500_126,TEM-1,beta-lactamase_2500,P62593,0.946582,NO,126,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.122,-4.816,3.694,,0.05,H,A,0.22,-0.05,0.817,,44.41,HPH,-1.60467,0.361275,0.00244552,0.946582 kka2_1:1_S204T,kka2_1:1_204,Kka2,kka2_1:1,P00552,0.946587,NO,204,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.353,-1.747,0.394,,0.144,E,A,0.27,-1.2,3.022,,65.53,HPO,-0.953333,0.520039,0.00881794,0.946587 beta-lactamase_0_D129T,beta-lactamase_0_129,TEM-1,beta-lactamase_0,P62593,0.946616,NO,129,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.816,-3.447,2.631,,,,B,0.75,-0.69,2.66,,34.97,PAP,-0.818,0.0500837,0.00109178,0.946616 beta-lactamase_0_E46Y,beta-lactamase_0_46,TEM-1,beta-lactamase_0,P62593,0.946622,NO,46,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.94,-4.198,2.258,,0.021,E,B,1.04,0.14,30.306,30.306,59.44,HAH,-2.079,0.0500837,0.00427568,0.946622 beta-lactamase_0_D252R,beta-lactamase_0_252,TEM-1,beta-lactamase_0,P62593,0.94667,NO,252,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.0500837,0.00575769,0.94667 beta-lactamase_156_A123Q,beta-lactamase_156_123,TEM-1,beta-lactamase_156,P62593,0.94668,NO,123,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.834,-3.948,3.114,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.111618,0.0010157,0.94668 Pab1_N132F,Pab1_132,Pab1,Pab1,P04147,0.946716,NO,132,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-1.079,-4.109,3.03,,0.412,S,l,,0.9,,,,BPH,-1.067,0.175299,0.000347671,0.946716 beta-lactamase_0_L79D,beta-lactamase_0_79,TEM-1,beta-lactamase_0,P62593,0.946724,NO,79,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.842,-4.141,3.299,,0.007,H,A,0.55,-0.16,5.053,,50.35,HHP,-1.44333,0.0500837,0.000947397,0.946724 beta-lactamase_A9N,beta-lactamase_9,TEM-1,beta-lactamase,P62593,0.946743,NO,9,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.147,-2.896,0.749,,,,,,,5.128,,72.73,HHH,-2.04267,0.221079,0.00247263,0.946743 beta-lactamase_K213T,beta-lactamase_213,TEM-1,beta-lactamase,P62593,0.946743,NO,213,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.81,-2.431,0.621,5.63167,0.67,,A,1.59,0.29,3.924,,67.83,ABH,-1.57767,0.221079,0.00610411,0.946743 beta-lactamase_K30I,beta-lactamase_30,TEM-1,beta-lactamase,P62593,0.946743,NO,30,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-2.307,-3.856,1.549,5.30605,0.142,H,A,1.82,-0.65,2.434,,93.01,HBH,-2.32833,0.221079,0.00448593,0.946743 beta-lactamase_T139C,beta-lactamase_139,TEM-1,beta-lactamase,P62593,0.946743,NO,139,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.901,-4.964,3.063,5.69095,0.216,H,A,0.3,0.39,2.256,,77.62,PPH,-2.04667,0.221079,0.00441837,0.946743 beta-lactamase_2500_G39L,beta-lactamase_2500_39,TEM-1,beta-lactamase_2500,P62593,0.946775,NO,39,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.864,-3.751,1.887,,0.701,T,L,0.29,0.47,29.926,29.926,77.62,HOH,-1.53633,0.361275,0.00487611,0.946775 beta-lactamase_0_D113A,beta-lactamase_0_113,TEM-1,beta-lactamase_0,P62593,0.946787,NO,113,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.829,-2.412,0.583,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.0500837,0.00474112,0.946787 kka2_1:4_L126M,kka2_1:4_126,Kka2,kka2_1:4,P00552,0.946788,NO,126,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.246,-4.129,2.883,,0.285,S,B,0.55,0.12,0.302,,51.89,PHA,-1.744,0.168804,0.0066485,0.946788 kka2_1:8_P167S,kka2_1:8_167,Kka2,kka2_1:8,P00552,0.946792,NO,167,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-2.403,-2.618,0.215,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.100394,0.00543203,0.946792 kka2_1:8_P167S,kka2_1:8_167,Kka2,kka2_1:8,P00552,0.946792,NO,167,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-2.403,-2.618,0.215,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.100394,0.00543203,0.946792 beta-lactamase_0_N173L,beta-lactamase_0_173,TEM-1,beta-lactamase_0,P62593,0.946803,NO,173,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-2.663,-3.749,1.086,,1.044,T,l,0.61,1.25,1.133,,77.62,OPA,-1.46633,0.0500837,0.0033769,0.946803 beta-lactamase_156_N134I,beta-lactamase_156_134,TEM-1,beta-lactamase_156,P62593,0.946834,NO,134,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-0.879,-4.036,3.157,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.111618,0.000644786,0.946834 beta-lactamase_39_D113A,beta-lactamase_39_113,TEM-1,beta-lactamase_39,P62593,0.94684,NO,113,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.829,-2.412,0.583,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.0495842,0.00474112,0.94684 beta-lactamase_39_R189K,beta-lactamase_39_189,TEM-1,beta-lactamase_39,P62593,0.94684,NO,189,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.844,-2.391,0.547,,0.278,H,A,1.2,1.01,12.11,12.11,72.73,HBB,-1.668,0.0495842,0.0050699,0.94684 beta-lactamase_39_D33W,beta-lactamase_39_33,TEM-1,beta-lactamase_39,P62593,0.946842,NO,33,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.321,-5.495,3.174,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.0495842,0.00435556,0.946842 beta-lactamase_0_L223P,beta-lactamase_0_223,TEM-1,beta-lactamase_0,P62593,0.946844,NO,223,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.055,-4.101,3.046,,0.27,,B,0.55,0.09,1.633,,74.48,HHO,-1.35033,0.0500837,0.00372793,0.946844 beta-lactamase_2500_P172I,beta-lactamase_2500_172,TEM-1,beta-lactamase_2500,P62593,0.946845,NO,172,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.998,-3.854,2.856,,0.639,T,b,0.52,0.24,4.99,,74.48,HOP,-2.03067,0.361275,0.00312594,0.946845 beta-lactamase_L100L,beta-lactamase_100,TEM-1,beta-lactamase,P62593,0.946866,NO,100,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.218,-1.218,,5.60291,0.343,,B,1.3,0.13,1.173,,63.29,AHH,-1.23467,0.221079,0.00413885,0.946866 Pab1_I128C,Pab1_128,Pab1,Pab1,P04147,0.946892,NO,128,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.345,-4.53,3.185,,0.008,E,B,1.68,-0.6,1.706,,78.68,PHH,-1.231,0.175299,0.00104192,0.946892 beta-lactamase_625_N274Q,beta-lactamase_625_274,TEM-1,beta-lactamase_625,P62593,0.946899,NO,274,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-2.082,-3.838,1.756,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.213352,0.0110418,0.946899 PSD95pdz3_E331H,PSD95pdz3_331,PSD95pdz3,PSD95pdz3,P31016,0.946916,NO,331,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.404,-3.912,2.508,5.86289,,,,,51.8889,,,,OAA,-1.22533,0.0758425,0.000950134,0.946916 Pab1_L191T,Pab1_191,Pab1,Pab1,P04147,0.946927,NO,191,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.2,-3.314,2.114,,0.204,E,B,,2.24,,,,HHP,-1.20133,0.175299,0.000583797,0.946927 beta-lactamase_0_P105F,beta-lactamase_0_105,TEM-1,beta-lactamase_0,P62593,0.946933,NO,105,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.813,-4.48,3.667,,0.226,T,A,0.52,0.8,3.48,,63.29,POH,-1.01533,0.0500837,0.0011981,0.946933 beta-lactamase_39_R239N,beta-lactamase_39_239,TEM-1,beta-lactamase_39,P62593,0.946937,NO,239,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.0495842,0.00213852,0.946937 beta-lactamase_2500_F58M,beta-lactamase_2500_58,TEM-1,beta-lactamase_2500,P62593,0.946943,NO,58,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-2.914,-4.667,1.753,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.361275,0.00523369,0.946943 PSD95pdz3_N369E,PSD95pdz3_369,PSD95pdz3,PSD95pdz3,P31016,0.946957,NO,369,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-1.572,-2.992,1.42,5.91569,,,,,24.1262,0.44,,87.71,BPH,-1.487,0.0758425,0.000608412,0.946957 beta-lactamase_I45Y,beta-lactamase_45,TEM-1,beta-lactamase,P62593,0.946958,NO,45,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-2.421,-2.914,0.493,5.31505,,E,B,1,-0.3,2.256,,77.62,HHA,-2.30267,0.221079,0.00452842,0.946958 beta-lactamase_2500_R81L,beta-lactamase_2500_81,TEM-1,beta-lactamase_2500,P62593,0.946959,NO,81,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.466,-2.766,1.3,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.361275,0.00499763,0.946959 beta-lactamase_2500_L111A,beta-lactamase_2500_111,TEM-1,beta-lactamase_2500,P62593,0.947047,NO,111,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.76,-2.229,0.469,,0.328,T,A,0.55,0.93,1.966,,64.34,BHP,-1.884,0.361275,0.00480671,0.947047 beta-lactamase_G251Y,beta-lactamase_251,TEM-1,beta-lactamase,P62593,0.947084,NO,251,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.907,-4.347,2.44,5.33865,0.506,T,l,0.73,0.17,10.663,,65.38,AOB,-2.06067,0.221079,0.00733416,0.947084 beta-lactamase_Q4T,beta-lactamase_4,TEM-1,beta-lactamase,P62593,0.947084,NO,4,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,,-3.329,0.765,,,,,,,,,,HPB,,0.221079,0.00316562,0.947084 beta-lactamase_2500_A225W,beta-lactamase_2500_225,TEM-1,beta-lactamase_2500,P62593,0.947114,NO,225,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.845,-5.541,3.696,,1,T,B,0.46,-0.38,0.551,,74.48,OHO,-1.39967,0.361275,0.00465057,0.947114 Pab1_G188C,Pab1_188,Pab1,Pab1,P04147,0.947144,NO,188,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.809,-4.904,4.095,,0.379,E,g,,2.18,,,,POH,-1.14633,0.175299,0.000280911,0.947144 beta-lactamase_625_K254P,beta-lactamase_625_254,TEM-1,beta-lactamase_625,P62593,0.947145,NO,254,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.213352,0.00369,0.947145 beta-lactamase_A40Q,beta-lactamase_40,TEM-1,beta-lactamase,P62593,0.947168,NO,40,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.402,-4.1,2.698,4.9697,0.155,S,B,1.2,0.21,1.714,,73.78,OHB,-1.40267,0.221079,0.00490026,0.947168 kka2_1:8_E17F,kka2_1:8_17,Kka2,kka2_1:8,P00552,0.947197,NO,17,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.154,-4.494,2.34,,0.957,T,A,1.04,0.22,31.483,31.483,63.64,HAB,-2.432,0.100394,0.00688738,0.947197 kka2_1:8_E17F,kka2_1:8_17,Kka2,kka2_1:8,P00552,0.947197,NO,17,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.154,-4.494,2.34,,0.957,T,A,1.04,0.22,31.483,31.483,63.64,HAB,-2.432,0.100394,0.00688738,0.947197 beta-lactamase_0_A235G,beta-lactamase_0_235,TEM-1,beta-lactamase_0,P62593,0.947215,NO,235,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.266,-2.075,0.809,,0.32,E,B,0.46,-0.86,2.261,,50,OHO,-0.89,0.0500837,0.00493474,0.947215 kka2_1:8_P12F,kka2_1:8_12,Kka2,kka2_1:8,P00552,0.947216,NO,12,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.853,-4.467,3.614,,,.,B,0.52,1.25,2.41,,48.11,POH,-1.80767,0.100394,0.00500011,0.947216 kka2_1:8_P12F,kka2_1:8_12,Kka2,kka2_1:8,P00552,0.947216,NO,12,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.853,-4.467,3.614,,,.,B,0.52,1.25,2.41,,48.11,POH,-1.80767,0.100394,0.00500011,0.947216 beta-lactamase_0_K144Q,beta-lactamase_0_144,TEM-1,beta-lactamase_0,P62593,0.947224,NO,144,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-2.388,-2.378,-0.01,,0.863,H,A,2.34,1.27,5.696,,77.62,OBA,-1.904,0.0500837,0.00481141,0.947224 beta-lactamase_2500_D271W,beta-lactamase_2500_271,TEM-1,beta-lactamase_2500,P62593,0.947237,NO,271,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.361275,0.00752082,0.947237 beta-lactamase_2500_E210V,beta-lactamase_2500_210,TEM-1,beta-lactamase_2500,P62593,0.947254,NO,210,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.319,-1.881,-0.438,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.361275,0.00663582,0.947254 Pab1_Y143Q,Pab1_143,Pab1,Pab1,P04147,0.947256,NO,143,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-1.961,-3.759,1.798,,0.409,H,A,,0.3,,,,HHA,-1.39633,0.175299,0.00160364,0.947256 Pab1_N187V,Pab1_187,Pab1,Pab1,P04147,0.947267,NO,187,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-1.224,-3.624,2.4,,0.456,S,b,,1.87,,,,HPO,-1.272,0.175299,0.00083165,0.947267 kka2_1:2_V153W,kka2_1:2_153,Kka2,kka2_1:2,P00552,0.947269,NO,153,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.092,-5.429,4.337,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.295029,0.00501119,0.947269 kka2_1:8_N58D,kka2_1:8_58,Kka2,kka2_1:8,P00552,0.947313,NO,58,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-2.641,-2.6,-0.041,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.100394,0.00793425,0.947313 kka2_1:8_N58D,kka2_1:8_58,Kka2,kka2_1:8,P00552,0.947313,NO,58,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-2.641,-2.6,-0.041,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.100394,0.00793425,0.947313 beta-lactamase_156_N134M,beta-lactamase_156_134,TEM-1,beta-lactamase_156,P62593,0.947322,NO,134,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-0.879,-4.702,3.823,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.111618,0.000644786,0.947322 beta-lactamase_2500_K32S,beta-lactamase_2500_32,TEM-1,beta-lactamase_2500,P62593,0.947325,NO,32,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.984,-3.371,1.387,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.361275,0.00401283,0.947325 Pab1_G163C,Pab1_163,Pab1,Pab1,P04147,0.947329,NO,163,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.809,-4.904,4.095,,0.356,B,g,,0.55,,,,POB,-1.80667,0.175299,0.00030953,0.947329 kka2_1:2_W24L,kka2_1:2_24,Kka2,kka2_1:2,P00552,0.947364,NO,24,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-1.779,-2.533,0.754,,0.477,E,B,1.51,-0.21,2.666,,56.06,AHH,-2.24467,0.295029,0.00631564,0.947364 PSD95pdz3_D357S,PSD95pdz3_357,PSD95pdz3,PSD95pdz3,P31016,0.947416,NO,357,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.264,-2.842,1.578,5.22306,,,,,10.975,,,,OAP,-1.32367,0.0758425,0.000609015,0.947416 kka2_1:8_E142W,kka2_1:8_142,Kka2,kka2_1:8,P00552,0.947486,NO,142,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.221,-5.578,3.357,,0.471,H,A,1.04,0.85,2.655,,65.53,HAB,-2.08033,0.100394,0.00748883,0.947486 kka2_1:8_E142W,kka2_1:8_142,Kka2,kka2_1:8,P00552,0.947486,NO,142,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.221,-5.578,3.357,,0.471,H,A,1.04,0.85,2.655,,65.53,HAB,-2.08033,0.100394,0.00748883,0.947486 beta-lactamase_2500_V260A,beta-lactamase_2500_260,TEM-1,beta-lactamase_2500,P62593,0.947508,NO,260,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.361275,0.00471757,0.947508 Pab1_E175T,Pab1_175,Pab1,Pab1,P04147,0.947555,NO,175,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.055,-2.077,0.022,,,,,,,,,,AAA,-1.82667,0.175299,0.00203137,0.947555 PSD95pdz3_I314K,PSD95pdz3_314,PSD95pdz3,PSD95pdz3,P31016,0.947566,NO,314,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.628,-3.588,1.96,5.39919,,,,,15.7775,0.397,,81.35,BHH,-1.61167,0.0758425,0.0012606,0.947566 beta-lactamase_F14L,beta-lactamase_14,TEM-1,beta-lactamase,P62593,0.947578,NO,14,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-2.736,-1.521,-1.215,,,,,,,1.537,,93.01,HHH,-2.26133,0.221079,0.00277095,0.947578 beta-lactamase_R271S,beta-lactamase_271,TEM-1,beta-lactamase,P62593,0.947578,NO,271,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.249,-3.414,2.165,5.24516,0.085,H,A,1.67,-0.05,0.474,,63.99,ABP,-1.36633,0.221079,0.00752082,0.947578 beta-lactamase_39_L137K,beta-lactamase_39_137,TEM-1,beta-lactamase_39,P62593,0.947579,NO,137,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.03,-3.749,2.719,,,H,A,0.55,-0.38,0.674,,42.31,HHP,-1.58933,0.0495842,0.00278599,0.947579 Pab1_S147D,Pab1_147,Pab1,Pab1,P04147,0.947588,NO,147,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.267,-3.164,1.897,,0.336,H,A,,0.56,,,,HPH,-1.43033,0.175299,0.000610856,0.947588 kka2_1:1_S114G,kka2_1:1_114,Kka2,kka2_1:1,P00552,0.947618,NO,114,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.527,-2.602,0.075,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.520039,0.00705262,0.947618 kka2_1:4_V16W,kka2_1:4_16,Kka2,kka2_1:4,P00552,0.94762,NO,16,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-3.087,-5.53,2.443,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.168804,0.00694011,0.94762 beta-lactamase_156_V101W,beta-lactamase_156_101,TEM-1,beta-lactamase_156,P62593,0.947626,NO,101,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.295,-5.385,4.09,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.111618,0.00374492,0.947626 beta-lactamase_0_I45A,beta-lactamase_0_45,TEM-1,beta-lactamase_0,P62593,0.947632,NO,45,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-2.421,-2.001,-0.42,,,E,B,0.48,-0.3,1.375,,77.62,HHA,-2.30267,0.0500837,0.00452842,0.947632 beta-lactamase_39_G39F,beta-lactamase_39_39,TEM-1,beta-lactamase_39,P62593,0.947649,NO,39,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.864,-4.451,2.587,,0.701,T,L,0.29,0.47,1.454,,77.62,HOH,-1.53633,0.0495842,0.00487611,0.947649 beta-lactamase_0_W163C,beta-lactamase_0_163,TEM-1,beta-lactamase_0,P62593,0.947661,NO,163,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-1.843,-5.117,3.274,,0.467,,B,0.47,-0.5,13.843,13.843,63.99,BHA,-1.269,0.0500837,0.00418955,0.947661 beta-lactamase_39_V117K,beta-lactamase_39_117,TEM-1,beta-lactamase_39,P62593,0.947662,NO,117,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.53,-3.844,2.314,,,H,A,0.44,-0.34,1.182,,65.03,PHB,-1.741,0.0495842,0.00467906,0.947662 kka2_1:1_F171L,kka2_1:1_171,Kka2,kka2_1:1,P00552,0.947669,NO,171,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.326,-1.818,0.492,,0.154,H,A,1.62,-0.1,13.679,13.679,63.64,HHH,-1.45433,0.520039,0.00821426,0.947669 kka2_1:4_L70M,kka2_1:4_70,Kka2,kka2_1:4,P00552,0.947682,NO,70,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.017,-2.172,1.155,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.168804,0.00411884,0.947682 kka2_1:8_L223V,kka2_1:8_223,Kka2,kka2_1:8,P00552,0.947718,NO,223,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.861,-2.827,1.966,,,H,A,1.59,-1.24,1.017,,50,HHH,-0.854333,0.100394,0.00253574,0.947718 kka2_1:8_L223V,kka2_1:8_223,Kka2,kka2_1:8,P00552,0.947718,NO,223,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.861,-2.827,1.966,,,H,A,1.59,-1.24,1.017,,50,HHH,-0.854333,0.100394,0.00253574,0.947718 kka2_1:2_A255Y,kka2_1:2_255,Kka2,kka2_1:2,P00552,0.947723,NO,255,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.715,-3.332,1.617,,0.466,H,A,0.46,-0.52,5.144,,65.53,HHH,-1.71267,0.295029,0.0126809,0.947723 beta-lactamase_0_R81N,beta-lactamase_0_81,TEM-1,beta-lactamase_0,P62593,0.947739,NO,81,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.466,-2.825,1.359,,0.218,H,A,1.2,1.66,0.332,,50,PBH,-1.60667,0.0500837,0.00499763,0.947739 Pab1_N139V,Pab1_139,Pab1,Pab1,P04147,0.947747,NO,139,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-1.079,-3.571,2.492,,0.062,H,A,,-0.73,,,,APB,-1.09667,0.175299,0.000339145,0.947747 beta-lactamase_A200L,beta-lactamase_200,TEM-1,beta-lactamase,P62593,0.947749,NO,200,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.878,-3.527,1.649,5.19406,0.757,H,A,0.47,-0.19,0.436,,77.62,HHP,-2.001,0.221079,0.0060056,0.947749 beta-lactamase_39_E61W,beta-lactamase_39_61,TEM-1,beta-lactamase_39,P62593,0.947781,NO,61,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.115,-5.544,3.429,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.0495842,0.00440955,0.947781 gb1_T243I,gb1_243,gb1,gb1,P06654,0.947809,NO,243,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.415,-3.371,1.956,,,,,,,1.083,,37.28,PPP,-1.43233,0.177985,0.00308687,0.947809 beta-lactamase_0_R81P,beta-lactamase_0_81,TEM-1,beta-lactamase_0,P62593,0.947815,NO,81,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.466,-3.949,2.483,,0.218,H,A,1.2,1.66,0.332,,50,PBH,-1.60667,0.0500837,0.00499763,0.947815 beta-lactamase_39_D252I,beta-lactamase_39_252,TEM-1,beta-lactamase_39,P62593,0.947829,NO,252,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.0495842,0.00575769,0.947829 kka2_1:1_W69G,kka2_1:1_69,Kka2,kka2_1:1,P00552,0.94783,NO,69,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-0.859,-3.43,2.571,,0.164,H,A,0.47,0.15,5.074,,38.64,PHH,-1.49967,0.520039,0.0012874,0.94783 beta-lactamase_L19P,beta-lactamase_19,TEM-1,beta-lactamase,P62593,0.947843,NO,19,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.682,-2.703,1.021,,,,,,,4.261,,93.01,OHO,-1.894,0.221079,0.00215974,0.947843 beta-lactamase_0_K71I,beta-lactamase_0_71,TEM-1,beta-lactamase_0,P62593,0.947869,NO,71,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-0.8,-4.01,3.21,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.0500837,0.00103192,0.947869 beta-lactamase_2500_M66I,beta-lactamase_2500_66,TEM-1,beta-lactamase_2500,P62593,0.947869,NO,66,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.362,-2.521,1.159,,0.013,,A,0.55,-0.7,0.502,,73.08,OHH,-1.49567,0.361275,0.00412876,0.947869 beta-lactamase_39_L150E,beta-lactamase_39_150,TEM-1,beta-lactamase_39,P62593,0.947898,NO,150,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.326,-3.822,2.496,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.0495842,0.00463171,0.947898 beta-lactamase_0_N168K,beta-lactamase_0_168,TEM-1,beta-lactamase_0,P62593,0.94794,NO,168,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-1.029,-3.307,2.278,,0.113,G,A,0.61,-0.4,0.881,,44.41,HPA,-1.13233,0.0500837,0.00288667,0.94794 beta-lactamase_625_N98C,beta-lactamase_625_98,TEM-1,beta-lactamase_625,P62593,0.947957,NO,98,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-2.973,-5.105,2.132,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.213352,0.00505389,0.947957 kka2_1:4_D159T,kka2_1:4_159,Kka2,kka2_1:4,P00552,0.947957,NO,159,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.82,-3.513,2.693,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.168804,0.0030485,0.947957 kka2_1:2_E142D,kka2_1:2_142,Kka2,kka2_1:2,P00552,0.947966,NO,142,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.221,-3.049,0.828,,0.471,H,A,1.52,0.85,3.693,,65.53,HAB,-2.08033,0.295029,0.00748883,0.947966 beta-lactamase_A276G,beta-lactamase_276,TEM-1,beta-lactamase,P62593,0.947996,NO,276,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.144,-3.11,1.966,5.1387,0.117,H,A,0.52,-0.84,1.283,,44.06,HHA,-1.47,0.221079,0.0191712,0.947996 kka2_1:4_E96H,kka2_1:4_96,Kka2,kka2_1:4,P00552,0.948021,NO,96,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.573,-4.74,2.167,,0.476,,B,1.52,-0.65,1.254,,71.59,OAH,-2.143,0.168804,0.00369441,0.948021 PSD95pdz3_V328Q,PSD95pdz3_328,PSD95pdz3,PSD95pdz3,P31016,0.948021,NO,328,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.465,-3.806,2.341,5.28275,,,,,16.8775,,,,HHO,-1.36767,0.0758425,0.000986706,0.948021 gb1_L231V,gb1_231,gb1,gb1,P06654,0.948031,NO,231,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.603,-2.865,1.262,,,,,,,0.219,,11.83,BHH,-1.82633,0.177985,0.00322797,0.948031 beta-lactamase_39_A215N,beta-lactamase_39_215,TEM-1,beta-lactamase_39,P62593,0.948045,NO,215,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.503,-3.679,2.176,,,,a,0.46,-0.93,0.494,,74.48,HHO,-1.42633,0.0495842,0.00544007,0.948045 beta-lactamase_A183Y,beta-lactamase_183,TEM-1,beta-lactamase,P62593,0.94805,NO,183,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.231,-4.261,3.03,4.84712,0.155,H,A,0.55,-0.91,12.189,,77.62,HHH,-1.53367,0.221079,0.00296631,0.94805 beta-lactamase_E210G,beta-lactamase_210,TEM-1,beta-lactamase,P62593,0.94805,NO,210,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.319,-3.66,1.341,5.7398,0.476,H,A,0.52,0.75,1.555,,77.62,HAH,-1.88567,0.221079,0.00663582,0.94805 kka2_1:4_G164K,kka2_1:4_164,Kka2,kka2_1:4,P00552,0.948056,NO,164,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.869,-3.652,2.783,,0.862,T,l,0.75,1.45,1.539,,64.39,POH,-1.828,0.168804,0.00442091,0.948056 beta-lactamase_0_G236R,beta-lactamase_0_236,TEM-1,beta-lactamase_0,P62593,0.948082,NO,236,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.784,-3.932,3.148,,0.241,,b,0.29,-0.59,3.506,,64.69,HOO,-1.025,0.0500837,0.00162372,0.948082 Pab1_D144L,Pab1_144,Pab1,Pab1,P04147,0.948085,NO,144,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.189,-3.622,2.433,,0.616,H,A,,0.6,,,,HAP,-1.40567,0.175299,0.00121131,0.948085 beta-lactamase_39_Q203W,beta-lactamase_39_203,TEM-1,beta-lactamase_39,P62593,0.948086,NO,203,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.168,-5.466,3.298,,0.47,H,A,0.64,-0.38,1.453,,65.38,BPP,-1.614,0.0495842,0.00631514,0.948086 Pab1_D136G,Pab1_136,Pab1,Pab1,P04147,0.9481,NO,136,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.602,-3.035,1.433,,,,,,,,,,OAH,-1.42367,0.175299,0.00227029,0.9481 beta-lactamase_0_P65L,beta-lactamase_0_65,TEM-1,beta-lactamase_0,P62593,0.948124,NO,65,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.894,-2.247,1.353,,0.098,E,B,0.52,-0.62,0.663,,40.56,HOH,-1.03233,0.0500837,0.00152776,0.948124 beta-lactamase_0_A225Q,beta-lactamase_0_225,TEM-1,beta-lactamase_0,P62593,0.948125,NO,225,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.845,-2.909,1.064,,1,T,B,0.46,-0.38,11.722,11.722,74.48,OHO,-1.39967,0.0500837,0.00465057,0.948125 Pab1_I196F,Pab1_196,Pab1,Pab1,P04147,0.948128,NO,196,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.795,-3.656,1.861,,,,,,,2.013,,80.59,AHH,-1.44667,0.175299,0.0016933,0.948128 beta-lactamase_39_I258S,beta-lactamase_39_258,TEM-1,beta-lactamase_39,P62593,0.948146,NO,258,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.0495842,0.007931,0.948146 beta-lactamase_0_E145T,beta-lactamase_0_145,TEM-1,beta-lactamase_0,P62593,0.948158,NO,145,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.357,-3.565,1.208,,0.545,H,A,1.04,0.79,1.199,,77.62,BAH,-2.069,0.0500837,0.00553285,0.948158 PSD95pdz3_R368Y,PSD95pdz3_368,PSD95pdz3,PSD95pdz3,P31016,0.94816,NO,368,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.582,-3.844,2.262,6.13355,,,,,18.1818,,,,HBP,-1.50033,0.0758425,0.000451517,0.94816 beta-lactamase_2500_R118V,beta-lactamase_2500_118,TEM-1,beta-lactamase_2500,P62593,0.948163,NO,118,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.413,-3.595,1.182,,0.457,H,A,1.2,1.39,2.144,,77.62,HBA,-1.785,0.361275,0.00538794,0.948163 beta-lactamase_T262E,beta-lactamase_262,TEM-1,beta-lactamase,P62593,0.948165,NO,262,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.332,-3.475,2.143,5.06002,0.108,E,B,0.3,-0.55,1.423,,67.83,PPO,-2.081,0.221079,0.00853516,0.948165 beta-lactamase_0_P60D,beta-lactamase_0_60,TEM-1,beta-lactamase_0,P62593,0.948188,NO,60,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-2.469,-3.676,1.207,,0.256,T,A,0.52,-0.56,3.653,,77.62,BOA,-1.97633,0.0500837,0.00521318,0.948188 beta-lactamase_0_A230P,beta-lactamase_0_230,TEM-1,beta-lactamase_0,P62593,0.94821,NO,230,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.154,-3.805,2.651,,0.01,E,B,0.46,-1.17,2.179,,50,HHA,-1.079,0.0500837,0.00516841,0.94821 beta-lactamase_2500_L136I,beta-lactamase_2500_136,TEM-1,beta-lactamase_2500,P62593,0.948218,NO,136,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.232,-1.874,0.642,,,H,A,0.55,-0.34,1.36,,48.95,HHH,-1.088,0.361275,0.00442304,0.948218 kka2_1:1_Q155Y,kka2_1:1_155,Kka2,kka2_1:1,P00552,0.948219,NO,155,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.606,-4.298,1.692,,0.525,T,A,0.4,1.49,4.415,,63.64,APA,-1.726,0.520039,0.00641853,0.948219 beta-lactamase_I278L,beta-lactamase_278,TEM-1,beta-lactamase,P62593,0.948224,NO,278,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.348,-1.998,0.65,5.35127,0.015,H,A,0.77,-0.85,2.718,,63.29,AHO,-1.41833,0.221079,0.0310297,0.948224 beta-lactamase_0_C75N,beta-lactamase_0_75,TEM-1,beta-lactamase_0,P62593,0.948226,NO,75,C,N,CN,Special,Polar,5.07,5.47157,0.401575,139,121,132,11,108.5,114.1,5.6,-1.245,-3.973,2.728,,,H,A,0.46,-0.87,2.256,,50,HOO,-1.24333,0.0500837,0.0034616,0.948226 kka2_1:2_G95A,kka2_1:2_95,Kka2,kka2_1:2,P00552,0.948232,NO,95,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-2.403,-3.101,0.698,,0.126,E,B,0.29,-0.74,0.359,,71.59,HOA,-2.198,0.295029,0.00743616,0.948232 beta-lactamase_0_E56W,beta-lactamase_0_56,TEM-1,beta-lactamase_0,P62593,0.948234,NO,56,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.043,-5.293,3.25,,0.198,E,B,1.04,0.31,1.491,,72.73,HAP,-1.94033,0.0500837,0.00238534,0.948234 beta-lactamase_0_S51Q,beta-lactamase_0_51,TEM-1,beta-lactamase_0,P62593,0.948257,NO,51,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.526,-3.91,2.384,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.0500837,0.00504821,0.948257 kka2_1:8_G201Q,kka2_1:8_201,Kka2,kka2_1:8,P00552,0.948276,NO,201,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.56,-4.001,2.441,,0.149,T,l,0.75,-0.57,2.152,,52.65,POB,-1.92233,0.100394,0.00820117,0.948276 kka2_1:8_G201Q,kka2_1:8_201,Kka2,kka2_1:8,P00552,0.948276,NO,201,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.56,-4.001,2.441,,0.149,T,l,0.75,-0.57,2.152,,52.65,POB,-1.92233,0.100394,0.00820117,0.948276 beta-lactamase_625_P224A,beta-lactamase_625_224,TEM-1,beta-lactamase_625,P62593,0.948277,NO,224,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.893,-3.071,2.178,,0.383,,B,0.52,-0.3,1.35,,74.48,HOH,-1.26433,0.213352,0.00189564,0.948277 beta-lactamase_2500_G226Q,beta-lactamase_2500_226,TEM-1,beta-lactamase_2500,P62593,0.948278,NO,226,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.461,-3.959,2.498,,0.701,T,l,0.29,-0.25,5.086,,74.48,HOH,-1.42933,0.361275,0.00665294,0.948278 Pab1_A158G,Pab1_158,Pab1,Pab1,P04147,0.948295,NO,158,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.154,-2.906,1.752,,,,,,,1.197,,56.33,HHP,-1.40733,0.175299,0.000649733,0.948295 kka2_1:4_T130W,kka2_1:4_130,Kka2,kka2_1:4,P00552,0.9483,NO,130,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.392,-5.541,3.149,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.168804,0.00804204,0.9483 beta-lactamase_0_A183F,beta-lactamase_0_183,TEM-1,beta-lactamase_0,P62593,0.948309,NO,183,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.231,-4.164,2.933,,0.155,H,A,0.46,-0.91,1.48,,77.62,HHH,-1.53367,0.0500837,0.00296631,0.948309 kka2_1:4_A65G,kka2_1:4_65,Kka2,kka2_1:4,P00552,0.948315,NO,65,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.744,-2.917,1.173,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.168804,0.00709258,0.948315 Pab1_G193F,Pab1_193,Pab1,Pab1,P04147,0.948335,NO,193,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.414,-4.238,2.824,,,,,,,,,,POP,-1.55733,0.175299,0.0014922,0.948335 beta-lactamase_0_G234L,beta-lactamase_0_234,TEM-1,beta-lactamase_0,P62593,0.948352,NO,234,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.62,-3.808,3.188,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.0500837,0.000889577,0.948352 kka2_1:8_E231K,kka2_1:8_231,Kka2,kka2_1:8,P00552,0.948353,NO,231,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.002,-3.423,1.421,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.100394,0.00732383,0.948353 kka2_1:8_E231K,kka2_1:8_231,Kka2,kka2_1:8,P00552,0.948353,NO,231,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.002,-3.423,1.421,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.100394,0.00732383,0.948353 kka2_1:8_L123R,kka2_1:8_123,Kka2,kka2_1:8,P00552,0.948353,NO,123,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.888,-4.001,3.113,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.100394,0.00325188,0.948353 kka2_1:8_L123R,kka2_1:8_123,Kka2,kka2_1:8,P00552,0.948353,NO,123,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.888,-4.001,3.113,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.100394,0.00325188,0.948353 beta-lactamase_H151I,beta-lactamase_151,TEM-1,beta-lactamase,P62593,0.948354,NO,151,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-2.96,-4.091,1.131,5.47408,0.594,H,A,0.35,0.1,1.843,,77.62,HBP,-2.34767,0.221079,0.00216946,0.948354 beta-lactamase_K53W,beta-lactamase_53,TEM-1,beta-lactamase,P62593,0.948354,NO,53,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-2.313,-2.612,0.299,5.93654,0.589,,B,1.82,1.15,19.72,19.72,77.62,OBH,-2.1,0.221079,0.00383383,0.948354 beta-lactamase_R7A,beta-lactamase_7,TEM-1,beta-lactamase,P62593,0.948354,NO,7,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.683,-3.065,1.382,,,,,,,2.44,,67.13,HBH,-1.96267,0.221079,0.00211375,0.948354 beta-lactamase_0_K109D,beta-lactamase_0_109,TEM-1,beta-lactamase_0,P62593,0.9484,NO,109,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.734,-2.919,1.185,,0.787,G,A,2.34,2.21,15.473,15.473,72.73,ABB,-1.63333,0.0500837,0.00462493,0.9484 PSD95pdz3_I377F,PSD95pdz3_377,PSD95pdz3,PSD95pdz3,P31016,0.948435,NO,377,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.873,-3.639,1.766,4.9532,,,,,19.185,2.364,,87.71,HHH,-1.49567,0.0758425,0.000795475,0.948435 beta-lactamase_156_Y44W,beta-lactamase_156_44,TEM-1,beta-lactamase_156,P62593,0.948465,NO,44,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-2.547,-5.1,2.553,,,E,B,0.21,-0.45,2.184,,73.78,OHH,-1.86267,0.111618,0.00426364,0.948465 Pab1_K140H,Pab1_140,Pab1,Pab1,P04147,0.948465,NO,140,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.083,-4.272,3.189,,0.345,H,A,,-0.73,,,,PBH,-1.20767,0.175299,0.000337366,0.948465 beta-lactamase_P172N,beta-lactamase_172,TEM-1,beta-lactamase,P62593,0.948468,NO,172,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.998,-3.875,2.877,5.98941,0.639,T,b,1.1,0.24,2.087,,74.48,HOP,-2.03067,0.221079,0.00312594,0.948468 beta-lactamase_39_T139Q,beta-lactamase_39_139,TEM-1,beta-lactamase_39,P62593,0.948477,NO,139,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.901,-2.8,0.899,,0.216,H,A,0.22,0.39,0.421,,77.62,PPH,-2.04667,0.0495842,0.00441837,0.948477 beta-lactamase_156_V42N,beta-lactamase_156_42,TEM-1,beta-lactamase_156,P62593,0.94849,NO,42,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.564,-4.165,2.601,,0.017,E,B,0.44,-0.51,2.576,,63.99,BHO,-1.042,0.111618,0.00404515,0.94849 beta-lactamase_2500_K144Y,beta-lactamase_2500_144,TEM-1,beta-lactamase_2500,P62593,0.948499,NO,144,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-2.388,-4.321,1.933,,0.863,H,A,2.34,1.27,0.515,,77.62,OBA,-1.904,0.361275,0.00481141,0.948499 kka2_1:4_R173G,kka2_1:4_173,Kka2,kka2_1:4,P00552,0.948507,NO,173,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.407,-3.552,1.145,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.168804,0.00784999,0.948507 kka2_1:1_R173M,kka2_1:1_173,Kka2,kka2_1:1,P00552,0.948543,NO,173,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.407,-4.764,2.357,,0.308,H,A,0.16,-0.13,14.756,14.756,65.53,HBH,-1.70533,0.520039,0.00784999,0.948543 kka2_1:4_H162C,kka2_1:4_162,Kka2,kka2_1:4,P00552,0.948603,NO,162,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-2.319,-5.188,2.869,,0.071,G,A,0.17,1.01,3.187,,64.39,ABP,-2.02067,0.168804,0.00616145,0.948603 beta-lactamase_39_W288D,beta-lactamase_39_288,TEM-1,beta-lactamase_39,P62593,0.948606,NO,288,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,,,,,,,,,,,,,BHO,,0.0495842,,0.948606 beta-lactamase_0_D231H,beta-lactamase_0_231,TEM-1,beta-lactamase_0,P62593,0.948611,NO,231,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.816,-4.453,3.637,,,E,B,0.75,-1.06,4.975,,65.38,HAB,-0.994,0.0500837,0.00107395,0.948611 beta-lactamase_2500_D99S,beta-lactamase_2500_99,TEM-1,beta-lactamase_2500,P62593,0.948651,NO,99,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.191,-3.286,2.095,,0.402,G,A,0.75,0.36,1.318,,64.69,PAH,-1.794,0.361275,0.00305446,0.948651 beta-lactamase_0_V214M,beta-lactamase_0_214,TEM-1,beta-lactamase_0,P62593,0.948667,NO,214,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.299,-4.251,2.952,,0.375,S,A,0.44,-0.44,3.712,,74.48,BHH,-1.53733,0.0500837,0.00628442,0.948667 kka2_1:4_C31V,kka2_1:4_31,Kka2,kka2_1:4,P00552,0.948672,NO,31,C,V,CV,Special,Hydrophobic,5.07,5.60847,0.538465,192,121,117,-4,108.5,140,31.5,-2.246,-2.747,0.501,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.168804,0.00681582,0.948672 beta-lactamase_X287C,beta-lactamase_287,TEM-1,beta-lactamase,P62593,0.948721,NO,287,X,C,XC,Stop,Special,5.71,5.07,-0.64,,132.5,121,-11,141.9,108.5,-33.4,,,,,,,,,,,,,HXO,-1.111,0.221079,,0.948721 beta-lactamase_0_A235V,beta-lactamase_0_235,TEM-1,beta-lactamase_0,P62593,0.948722,NO,235,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.266,-2.665,1.399,,0.32,E,B,0.46,-0.86,2.261,,50,OHO,-0.89,0.0500837,0.00493474,0.948722 beta-lactamase_0_S241H,beta-lactamase_0_241,TEM-1,beta-lactamase_0,P62593,0.948729,NO,241,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.0500837,0.00452736,0.948729 kka2_1:8_P45L,kka2_1:8_45,Kka2,kka2_1:8,P00552,0.948756,NO,45,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.774,-3.048,1.274,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.100394,0.00590481,0.948756 kka2_1:8_P45L,kka2_1:8_45,Kka2,kka2_1:8,P00552,0.948756,NO,45,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.774,-3.048,1.274,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.100394,0.00590481,0.948756 beta-lactamase_39_A123Q,beta-lactamase_39_123,TEM-1,beta-lactamase_39,P62593,0.948795,NO,123,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.834,-3.948,3.114,,0.039,H,A,0.46,-0.72,0.705,,41.26,PHH,-1.47367,0.0495842,0.0010157,0.948795 beta-lactamase_0_L135F,beta-lactamase_0_135,TEM-1,beta-lactamase_0,P62593,0.948856,NO,135,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.002,-3.671,2.669,,0.117,H,A,0.55,-0.58,0.705,,43.71,PHH,-1.03767,0.0500837,0.00244423,0.948856 beta-lactamase_S221G,beta-lactamase_221,TEM-1,beta-lactamase,P62593,0.948857,NO,221,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.754,-3.136,1.382,5.77407,0.624,H,A,0.74,-0.2,0.383,,74.48,BPH,-1.59967,0.221079,0.0046094,0.948857 beta-lactamase_2500_A278V,beta-lactamase_2500_278,TEM-1,beta-lactamase_2500,P62593,0.948859,NO,278,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.361275,0.0310297,0.948859 beta-lactamase_G90L,beta-lactamase_90,TEM-1,beta-lactamase,P62593,0.948861,NO,90,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-2.091,-3.689,1.598,5.51991,0.598,T,A,0.23,0.32,1.791,,77.62,HOB,-1.52633,0.221079,0.00490273,0.948861 beta-lactamase_2500_D99H,beta-lactamase_2500_99,TEM-1,beta-lactamase_2500,P62593,0.948863,NO,99,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.191,-3.065,1.874,,0.402,G,A,0.75,0.36,1.318,,64.69,PAH,-1.794,0.361275,0.00305446,0.948863 beta-lactamase_156_I258T,beta-lactamase_156_258,TEM-1,beta-lactamase_156,P62593,0.948864,NO,258,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.111618,0.007931,0.948864 kka2_1:8_D180V,kka2_1:8_180,Kka2,kka2_1:8,P00552,0.948871,NO,180,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.416,-3.003,0.587,,1.03,S,a,0.75,1.5,14.668,14.668,71.59,OAO,-2.02933,0.100394,0.00756412,0.948871 kka2_1:8_D180V,kka2_1:8_180,Kka2,kka2_1:8,P00552,0.948871,NO,180,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.416,-3.003,0.587,,1.03,S,a,0.75,1.5,14.668,14.668,71.59,OAO,-2.02933,0.100394,0.00756412,0.948871 beta-lactamase_2500_T269M,beta-lactamase_2500_269,TEM-1,beta-lactamase_2500,P62593,0.948875,NO,269,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.361275,0.00950944,0.948875 beta-lactamase_39_A170Y,beta-lactamase_39_170,TEM-1,beta-lactamase_39,P62593,0.948885,NO,170,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.237,-4.057,2.82,,0.126,,L,0.46,-0.35,3.7,,64.69,AHH,-1.63267,0.0495842,0.00431903,0.948885 kka2_1:8_L107P,kka2_1:8_107,Kka2,kka2_1:8,P00552,0.94891,NO,107,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.238,-4.14,2.902,,0.197,.,B,0.55,-1.1,4.478,,71.59,BHH,-2.143,0.100394,0.00561937,0.94891 kka2_1:8_L107P,kka2_1:8_107,Kka2,kka2_1:8,P00552,0.94891,NO,107,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.238,-4.14,2.902,,0.197,.,B,0.55,-1.1,4.478,,71.59,BHH,-2.143,0.100394,0.00561937,0.94891 PSD95pdz3_F340C,PSD95pdz3_340,PSD95pdz3,PSD95pdz3,P31016,0.948916,NO,340,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.524,-4.544,3.02,5.79283,,,,,11.8045,,,,PHH,-1.55767,0.0758425,0.000836987,0.948916 kka2_1:8_L47A,kka2_1:8_47,Kka2,kka2_1:8,P00552,0.948929,NO,47,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.265,-2.449,1.184,,0.139,E,B,1.59,-0.86,5.086,,63.26,HHH,-1.77933,0.100394,0.00509386,0.948929 kka2_1:8_L47A,kka2_1:8_47,Kka2,kka2_1:8,P00552,0.948929,NO,47,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.265,-2.449,1.184,,0.139,E,B,1.59,-0.86,5.086,,63.26,HHH,-1.77933,0.100394,0.00509386,0.948929 beta-lactamase_39_T178N,beta-lactamase_39_178,TEM-1,beta-lactamase_39,P62593,0.948933,NO,178,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-0.791,-3.448,2.657,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.0495842,0.000684366,0.948933 beta-lactamase_A34T,beta-lactamase_34,TEM-1,beta-lactamase,P62593,0.948935,NO,34,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.059,-2.5,0.441,4.9129,,H,A,0.75,-0.54,3.614,,73.78,AHA,-1.74967,0.221079,0.00407913,0.948935 beta-lactamase_R41A,beta-lactamase_41,TEM-1,beta-lactamase,P62593,0.948935,NO,41,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-0.942,-3.041,2.099,5.69185,0.321,E,B,0.91,-0.07,4.357,,65.03,HBH,-1.30267,0.221079,0.00123327,0.948935 beta-lactamase_625_E169P,beta-lactamase_625_169,TEM-1,beta-lactamase_625,P62593,0.948938,NO,169,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.23,-3.768,2.538,,0.337,,A,1.04,1,1.806,,73.08,PAH,-1.16533,0.213352,0.00400994,0.948938 beta-lactamase_0_S233W,beta-lactamase_0_233,TEM-1,beta-lactamase_0,P62593,0.948955,NO,233,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.886,-5.339,3.453,,0.016,E,B,0.27,-1.01,3.579,,77.62,BPO,-1.17267,0.0500837,0.00311415,0.948955 beta-lactamase_0_K213Y,beta-lactamase_0_213,TEM-1,beta-lactamase_0,P62593,0.948986,NO,213,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.81,-4.305,2.495,,0.67,,A,2.34,0.29,3.015,,67.83,ABH,-1.57767,0.0500837,0.00610411,0.948986 Pab1_V148A,Pab1_148,Pab1,Pab1,P04147,0.948996,NO,148,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.875,-1.743,-0.132,,,,,,,,,,PHH,-1.43033,0.175299,0.00179641,0.948996 kka2_1:2_S114C,kka2_1:2_114,Kka2,kka2_1:2,P00552,0.949,NO,114,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.527,-5.142,2.615,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.295029,0.00705262,0.949 Pab1_S155G,Pab1_155,Pab1,Pab1,P04147,0.949041,NO,155,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.039,-3.285,1.246,,,,,,,,,,PPB,-1.42267,0.175299,0.00208179,0.949041 kka2_1:8_A172P,kka2_1:8_172,Kka2,kka2_1:8,P00552,0.949044,NO,172,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.757,-4.041,2.284,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.100394,0.0079265,0.949044 kka2_1:8_A172P,kka2_1:8_172,Kka2,kka2_1:8,P00552,0.949044,NO,172,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.757,-4.041,2.284,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.100394,0.0079265,0.949044 Pab1_I152V,Pab1_152,Pab1,Pab1,P04147,0.949051,NO,152,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.345,-1.656,0.311,,0.165,E,B,1.23,-0.71,1.288,,71.4,AHH,-1.59433,0.175299,0.000740963,0.949051 beta-lactamase_L160T,beta-lactamase_160,TEM-1,beta-lactamase,P62593,0.949052,NO,160,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.977,-3.438,2.461,5.32068,0.022,,B,1.75,-0.6,0.895,,44.41,BHA,-0.936,0.221079,0.00193775,0.949052 Pab1_V171I,Pab1_171,Pab1,Pab1,P04147,0.949058,NO,171,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.113,-2.477,1.364,,0.008,E,b,0.23,-0.34,,,,HHB,-1.19733,0.175299,0.000298662,0.949058 beta-lactamase_156_G249A,beta-lactamase_156_249,TEM-1,beta-lactamase_156,P62593,0.949059,NO,249,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.111618,0.00220169,0.949059 PSD95pdz3_F340R,PSD95pdz3_340,PSD95pdz3,PSD95pdz3,P31016,0.949069,NO,340,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.524,-3.84,2.316,5.79283,,,,,11.8045,,,,PHH,-1.55767,0.0758425,0.000836987,0.949069 kka2_1:2_R253L,kka2_1:2_253,Kka2,kka2_1:2,P00552,0.949087,NO,253,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.356,-3.455,2.099,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.295029,0.0144195,0.949087 beta-lactamase_0_K144I,beta-lactamase_0_144,TEM-1,beta-lactamase_0,P62593,0.949088,NO,144,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-2.388,-4.014,1.626,,0.863,H,A,2.34,1.27,5.696,,77.62,OBA,-1.904,0.0500837,0.00481141,0.949088 beta-lactamase_T147G,beta-lactamase_147,TEM-1,beta-lactamase,P62593,0.949112,NO,147,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.149,-2.499,1.35,5.37474,0.281,H,A,0.8,-0.68,2.838,,64.34,HPH,-1.456,0.221079,0.00226017,0.949112 beta-lactamase_2500_K144C,beta-lactamase_2500_144,TEM-1,beta-lactamase_2500,P62593,0.949117,NO,144,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-2.388,-5.107,2.719,,0.863,H,A,2.34,1.27,0.515,,77.62,OBA,-1.904,0.361275,0.00481141,0.949117 kka2_1:4_G151A,kka2_1:4_151,Kka2,kka2_1:4,P00552,0.949124,NO,151,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.873,-3.018,2.145,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.168804,0.00339918,0.949124 beta-lactamase_625_V101H,beta-lactamase_625_101,TEM-1,beta-lactamase_625,P62593,0.949146,NO,101,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.295,-4.92,3.625,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.213352,0.00374492,0.949146 beta-lactamase_0_N50T,beta-lactamase_0_50,TEM-1,beta-lactamase_0,P62593,0.949156,NO,50,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-2.979,-2.678,-0.301,,0.912,T,A,0.61,1.24,9.874,9.874,77.62,HPP,-2.134,0.0500837,0.0047211,0.949156 beta-lactamase_39_K30I,beta-lactamase_39_30,TEM-1,beta-lactamase_39,P62593,0.94916,NO,30,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-2.307,-3.856,1.549,,0.142,H,A,2.34,-0.65,6.717,,93.01,HBH,-2.32833,0.0495842,0.00448593,0.94916 Pab1_N132Y,Pab1_132,Pab1,Pab1,P04147,0.949184,NO,132,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-1.079,-3.98,2.901,,0.412,S,l,,0.9,,,,BPH,-1.067,0.175299,0.000347671,0.949184 beta-lactamase_625_D252K,beta-lactamase_625_252,TEM-1,beta-lactamase_625,P62593,0.949188,NO,252,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.94,-3.575,1.635,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.213352,0.00575769,0.949188 kka2_1:2_G74S,kka2_1:2_74,Kka2,kka2_1:2,P00552,0.949189,NO,74,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.18,-2.717,1.537,,0.621,T,l,0.75,0.2,1.446,,64.39,POH,-1.91667,0.295029,0.00587035,0.949189 kka2_1:8_E182N,kka2_1:8_182,Kka2,kka2_1:8,P00552,0.949203,NO,182,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.516,-3.686,2.17,,0.326,,B,1.52,0.75,2.568,,65.53,OAA,-1.806,0.100394,0.00641548,0.949203 kka2_1:8_E182N,kka2_1:8_182,Kka2,kka2_1:8,P00552,0.949203,NO,182,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.516,-3.686,2.17,,0.326,,B,1.52,0.75,2.568,,65.53,OAA,-1.806,0.100394,0.00641548,0.949203 PSD95pdz3_D357E,PSD95pdz3_357,PSD95pdz3,PSD95pdz3,P31016,0.949229,NO,357,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.264,-2.447,1.183,5.22306,,,,,10.975,,,,OAP,-1.32367,0.0758425,0.000609015,0.949229 kka2_1:4_E149G,kka2_1:4_149,Kka2,kka2_1:4,P00552,0.949248,NO,149,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.994,-3.566,1.572,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.168804,0.00803343,0.949248 beta-lactamase_2500_G216N,beta-lactamase_2500_216,TEM-1,beta-lactamase_2500,P62593,0.949253,NO,216,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.477,-2.771,1.294,,0.437,I,A,0.29,-0.58,1.983,,74.48,HOO,-1.68067,0.361275,0.00639568,0.949253 beta-lactamase_0_G39V,beta-lactamase_0_39,TEM-1,beta-lactamase_0,P62593,0.949272,NO,39,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.864,-3.813,1.949,,0.701,T,L,0.29,0.47,4.111,,77.62,HOH,-1.53633,0.0500837,0.00487611,0.949272 beta-lactamase_2500_Q203N,beta-lactamase_2500_203,TEM-1,beta-lactamase_2500,P62593,0.949283,NO,203,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.168,-3.727,1.559,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.361275,0.00631514,0.949283 kka2_1:8_A64P,kka2_1:8_64,Kka2,kka2_1:8,P00552,0.949286,NO,64,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.496,-4.02,2.524,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.100394,0.00705578,0.949286 kka2_1:8_A64P,kka2_1:8_64,Kka2,kka2_1:8,P00552,0.949286,NO,64,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.496,-4.02,2.524,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.100394,0.00705578,0.949286 kka2_1:8_R121S,kka2_1:8_121,Kka2,kka2_1:8,P00552,0.949293,NO,121,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.552,-2.658,1.106,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.100394,0.00523326,0.949293 kka2_1:8_R121S,kka2_1:8_121,Kka2,kka2_1:8,P00552,0.949293,NO,121,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.552,-2.658,1.106,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.100394,0.00523326,0.949293 PSD95pdz3_N381W,PSD95pdz3_381,PSD95pdz3,PSD95pdz3,P31016,0.9493,NO,381,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-1.41,-5.229,3.819,5.66057,,,,,28.2162,,,,BPH,-1.37767,0.0758425,0.000265374,0.9493 kka2_1:8_R253S,kka2_1:8_253,Kka2,kka2_1:8,P00552,0.949332,NO,253,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.356,-3.389,2.033,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.100394,0.0144195,0.949332 kka2_1:8_R253S,kka2_1:8_253,Kka2,kka2_1:8,P00552,0.949332,NO,253,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.356,-3.389,2.033,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.100394,0.0144195,0.949332 beta-lactamase_0_R257N,beta-lactamase_0_257,TEM-1,beta-lactamase_0,P62593,0.949352,NO,257,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.0500837,0.00756629,0.949352 beta-lactamase_0_D231W,beta-lactamase_0_231,TEM-1,beta-lactamase_0,P62593,0.949353,NO,231,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.816,-5.545,4.729,,,E,B,0.75,-1.06,4.975,,65.38,HAB,-0.994,0.0500837,0.00107395,0.949353 beta-lactamase_39_G249K,beta-lactamase_39_249,TEM-1,beta-lactamase_39,P62593,0.949353,NO,249,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.312,,,,0.256,S,B,0.23,0.04,30.841,30.841,72.73,HOO,-1.81367,0.0495842,0.00220169,0.949353 Pab1_A185G,Pab1_185,Pab1,Pab1,P04147,0.949383,NO,185,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.702,-2.014,0.312,,,,,,,1.756,,63.26,AHH,-1.66167,0.175299,0.00144499,0.949383 WW_domain_M179T,WW_domain_179,Yap65,WW_domain,P46937,0.949391,NO,179,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.541,-3.198,1.657,6.54704,,,,,,,,,AHH,-1.31367,0.153962,0.00400164,0.949391 beta-lactamase_0_T187L,beta-lactamase_0_187,TEM-1,beta-lactamase_0,P62593,0.949397,NO,187,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.401,-2.278,0.877,,0.007,H,A,0.22,-1.19,3.259,,67.48,PPH,-1.69633,0.0500837,0.00491782,0.949397 beta-lactamase_39_E210C,beta-lactamase_39_210,TEM-1,beta-lactamase_39,P62593,0.949423,NO,210,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.319,-4.991,2.672,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.0495842,0.00663582,0.949423 kka2_1:4_A229W,kka2_1:4_229,Kka2,kka2_1:4,P00552,0.949453,NO,229,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.739,-5.507,3.768,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.168804,0.00942138,0.949453 beta-lactamase_0_A247R,beta-lactamase_0_247,TEM-1,beta-lactamase_0,P62593,0.949458,NO,247,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.0500837,0.00611275,0.949458 beta-lactamase_V21T,beta-lactamase_21,TEM-1,beta-lactamase,P62593,0.949502,NO,21,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.873,-3.301,1.428,,,,,,,0.688,,93.01,OHH,-2.09633,0.221079,0.0028612,0.949502 beta-lactamase_2500_P172N,beta-lactamase_2500_172,TEM-1,beta-lactamase_2500,P62593,0.949518,NO,172,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.998,-3.875,2.877,,0.639,T,b,0.52,0.24,4.99,,74.48,HOP,-2.03067,0.361275,0.00312594,0.949518 beta-lactamase_0_L167S,beta-lactamase_0_167,TEM-1,beta-lactamase_0,P62593,0.949532,NO,167,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.138,-2.747,1.609,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.0500837,0.00303566,0.949532 beta-lactamase_39_T139M,beta-lactamase_39_139,TEM-1,beta-lactamase_39,P62593,0.949539,NO,139,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.901,-4.659,2.758,,0.216,H,A,0.22,0.39,0.421,,77.62,PPH,-2.04667,0.0495842,0.00441837,0.949539 beta-lactamase_0_V29H,beta-lactamase_0_29,TEM-1,beta-lactamase_0,P62593,0.94955,NO,29,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-2.856,-4.571,1.715,,0.733,H,A,0.44,-0.78,21.916,21.916,93.01,HHB,-2.24733,0.0500837,0.00318969,0.94955 kka2_1:4_W24I,kka2_1:4_24,Kka2,kka2_1:4,P00552,0.949556,NO,24,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-1.779,-2.156,0.377,,0.477,E,B,1.51,-0.21,2.666,,56.06,AHH,-2.24467,0.168804,0.00631564,0.949556 Pab1_H134E,Pab1_134,Pab1,Pab1,P04147,0.949584,NO,134,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-1.542,-3.005,1.463,,,,,,,,,,HBO,-1.346,0.175299,0.00116356,0.949584 kka2_1:8_P132G,kka2_1:8_132,Kka2,kka2_1:8,P00552,0.949609,NO,132,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.775,-3.354,2.579,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.100394,0.0018489,0.949609 kka2_1:8_P132G,kka2_1:8_132,Kka2,kka2_1:8,P00552,0.949609,NO,132,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.775,-3.354,2.579,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.100394,0.0018489,0.949609 kka2_1:4_E63L,kka2_1:4_63,Kka2,kka2_1:4,P00552,0.949612,NO,63,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-0.762,-3.611,2.849,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.168804,0.00118399,0.949612 beta-lactamase_0_P65A,beta-lactamase_0_65,TEM-1,beta-lactamase_0,P62593,0.949659,NO,65,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.894,-3.096,2.202,,0.098,E,B,0.52,-0.62,0.663,,40.56,HOH,-1.03233,0.0500837,0.00152776,0.949659 beta-lactamase_0_E56F,beta-lactamase_0_56,TEM-1,beta-lactamase_0,P62593,0.949677,NO,56,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.043,-4.191,2.148,,0.198,E,B,1.04,0.31,1.491,,72.73,HAP,-1.94033,0.0500837,0.00238534,0.949677 beta-lactamase_2500_E279V,beta-lactamase_2500_279,TEM-1,beta-lactamase_2500,P62593,0.949717,NO,279,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.361275,0.0192826,0.949717 beta-lactamase_625_D48C,beta-lactamase_625_48,TEM-1,beta-lactamase_625,P62593,0.949737,NO,48,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.101,-5.125,4.024,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.213352,0.0027273,0.949737 hsp90_E590F,hsp90_590,hsp90,hsp90,P02829,0.949748,NO,590,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.818,-3.22,0,4.65049,0.021,H,A,,0.03,,,,HAO,-3.338,0.368192,0.000222939,0.949748 beta-lactamase_A280F,beta-lactamase_280,TEM-1,beta-lactamase,P62593,0.94975,NO,280,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.708,-4.279,2.571,4.74932,0.379,H,A,0.52,-0.72,1.785,,68.18,OHP,-1.66433,0.221079,0.0530888,0.94975 beta-lactamase_A84Y,beta-lactamase_84,TEM-1,beta-lactamase,P62593,0.94975,NO,84,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.651,-4.29,2.639,5.28927,0.65,T,A,0.52,0.96,1.863,,68.18,AHO,-1.24267,0.221079,0.00503822,0.94975 beta-lactamase_D269W,beta-lactamase_269,TEM-1,beta-lactamase,P62593,0.94975,NO,269,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.156,-5.588,3.432,5.47645,0.646,H,A,0.23,0.4,21.796,21.796,77.62,HAA,-1.96733,0.221079,0.00950944,0.94975 beta-lactamase_G39M,beta-lactamase_39,TEM-1,beta-lactamase,P62593,0.94975,NO,39,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.864,-4.879,3.015,5.35574,0.701,T,L,0.23,0.47,29.926,29.926,77.62,HOH,-1.53633,0.221079,0.00487611,0.94975 beta-lactamase_G39Y,beta-lactamase_39,TEM-1,beta-lactamase,P62593,0.94975,NO,39,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.864,-4.383,2.519,5.35574,0.701,T,L,0.23,0.47,29.926,29.926,77.62,HOH,-1.53633,0.221079,0.00487611,0.94975 beta-lactamase_L28A,beta-lactamase_28,TEM-1,beta-lactamase,P62593,0.94975,NO,28,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.579,-2.126,0.547,5.42969,0.277,H,A,0.07,-0.16,19.748,19.748,93.01,PHH,-2.11333,0.221079,0.00359321,0.94975 beta-lactamase_P25W,beta-lactamase_25,TEM-1,beta-lactamase,P62593,0.94975,NO,25,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.526,-5.419,3.893,5.6134,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.221079,0.00347571,0.94975 beta-lactamase_Q4F,beta-lactamase_4,TEM-1,beta-lactamase,P62593,0.94975,NO,4,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,,-4.2,1.636,,,,,,,,,,HPB,,0.221079,0.00316562,0.94975 beta-lactamase_V117M,beta-lactamase_117,TEM-1,beta-lactamase,P62593,0.94975,NO,117,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.53,-3.063,1.533,5.33594,,H,A,1.19,-0.34,1.182,,65.03,PHB,-1.741,0.221079,0.00467906,0.94975 beta-lactamase_0_T263A,beta-lactamase_0_263,TEM-1,beta-lactamase_0,P62593,0.949761,NO,263,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.0500837,0.0110582,0.949761 Pab1_S147Y,Pab1_147,Pab1,Pab1,P04147,0.949765,NO,147,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.267,-4.033,2.766,,0.336,H,A,,0.56,,,,HPH,-1.43033,0.175299,0.000610856,0.949765 beta-lactamase_0_E108W,beta-lactamase_0_108,TEM-1,beta-lactamase_0,P62593,0.949768,NO,108,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.46,-5.465,4.005,,0.572,G,A,1.04,1.87,8.602,8.602,72.73,PAB,-1.437,0.0500837,0.00413372,0.949768 kka2_1:8_S204R,kka2_1:8_204,Kka2,kka2_1:8,P00552,0.949791,NO,204,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.353,-3.873,2.52,,0.144,E,A,0.27,-1.2,0.368,,65.53,HPO,-0.953333,0.100394,0.00881794,0.949791 kka2_1:8_S204R,kka2_1:8_204,Kka2,kka2_1:8,P00552,0.949791,NO,204,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.353,-3.873,2.52,,0.144,E,A,0.27,-1.2,0.368,,65.53,HPO,-0.953333,0.100394,0.00881794,0.949791 beta-lactamase_R159R,beta-lactamase_159,TEM-1,beta-lactamase,P62593,0.949799,NO,159,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-0.94,-0.94,,5.64971,0.316,,B,0.68,-0.55,1.172,,64.34,PBH,-1.011,0.221079,0.00108472,0.949799 beta-lactamase_2500_S221L,beta-lactamase_2500_221,TEM-1,beta-lactamase_2500,P62593,0.949813,NO,221,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.754,-3.35,1.596,,0.624,H,A,0.27,-0.2,1.971,,74.48,BPH,-1.59967,0.361275,0.0046094,0.949813 Pab1_Y197R,Pab1_197,Pab1,Pab1,P04147,0.949865,NO,197,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-1.345,-3.928,2.583,,,,,,,0.891,,80.42,HHH,-1.41767,0.175299,0.00302474,0.949865 beta-lactamase_625_V82G,beta-lactamase_625_82,TEM-1,beta-lactamase_625,P62593,0.949878,NO,82,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.325,-2.644,1.319,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.213352,0.00397046,0.949878 Pab1_I128M,Pab1_128,Pab1,Pab1,P04147,0.949897,NO,128,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.345,-3.923,2.578,,0.008,E,B,1.68,-0.6,1.706,,78.68,PHH,-1.231,0.175299,0.00104192,0.949897 kka2_1:4_Q163G,kka2_1:4_163,Kka2,kka2_1:4,P00552,0.949915,NO,163,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.162,-3.698,1.536,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.168804,0.00719507,0.949915 PSD95pdz3_I389D,PSD95pdz3_389,PSD95pdz3,PSD95pdz3,P31016,0.949919,NO,389,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.628,-3.696,2.068,5.15116,,,,,14.8038,1.498,,87.71,HHH,-1.52167,0.0758425,0.00148097,0.949919 beta-lactamase_39_K254Q,beta-lactamase_39_254,TEM-1,beta-lactamase_39,P62593,0.949921,NO,254,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.0495842,0.00369,0.949921 kka2_1:8_F256L,kka2_1:8_256,Kka2,kka2_1:8,P00552,0.949925,NO,256,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.49,-3.235,1.745,,,H,A,1.62,-0.78,1.713,,53.03,HHH,-1.423,0.100394,0.0132841,0.949925 kka2_1:8_F256L,kka2_1:8_256,Kka2,kka2_1:8,P00552,0.949925,NO,256,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.49,-3.235,1.745,,,H,A,1.62,-0.78,1.713,,53.03,HHH,-1.423,0.100394,0.0132841,0.949925 beta-lactamase_2500_T139C,beta-lactamase_2500_139,TEM-1,beta-lactamase_2500,P62593,0.949943,NO,139,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.901,-4.964,3.063,,0.216,H,A,0.22,0.39,2.256,,77.62,PPH,-2.04667,0.361275,0.00441837,0.949943 PSD95pdz3_G351F,PSD95pdz3_351,PSD95pdz3,PSD95pdz3,P31016,0.949968,NO,351,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.008,-3.974,2.966,5.44798,,,,,20.7625,,,,POA,-1.37133,0.0758425,0.000691282,0.949968 beta-lactamase_39_M180H,beta-lactamase_39_180,TEM-1,beta-lactamase_39,P62593,0.949972,NO,180,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-2.795,-4.627,1.832,,0.242,,B,0.55,-0.94,3.579,,77.62,PHO,-1.56433,0.0495842,0.00552048,0.949972 beta-lactamase_R81A,beta-lactamase_81,TEM-1,beta-lactamase,P62593,0.950007,NO,81,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.466,-2.609,1.143,5.12166,0.218,H,A,0.68,1.66,1.236,,50,PBH,-1.60667,0.221079,0.00499763,0.950007 beta-lactamase_0_L248C,beta-lactamase_0_248,TEM-1,beta-lactamase_0,P62593,0.950053,NO,248,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.0500837,0.00428493,0.950053 beta-lactamase_39_D99W,beta-lactamase_39_99,TEM-1,beta-lactamase_39,P62593,0.950085,NO,99,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.191,-5.462,4.271,,0.402,G,A,0.75,0.36,0.374,,64.69,PAH,-1.794,0.0495842,0.00305446,0.950085 beta-lactamase_39_E62K,beta-lactamase_39_62,TEM-1,beta-lactamase_39,P62593,0.950088,NO,62,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.193,-3.246,2.053,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.0495842,0.00264802,0.950088 beta-lactamase_39_A222C,beta-lactamase_39_222,TEM-1,beta-lactamase_39,P62593,0.95009,NO,222,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.103,-4.939,2.836,,0.233,H,A,0.46,-0.25,1.448,,77.62,PHH,-1.63733,0.0495842,0.00466094,0.95009 Pab1_A199S,Pab1_199,Pab1,Pab1,P04147,0.950094,NO,199,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.53,-2.943,1.413,,,,,,,1.479,,80.42,HHO,-1.50467,0.175299,0.00145024,0.950094 beta-lactamase_A77T,beta-lactamase_77,TEM-1,beta-lactamase,P62593,0.950099,NO,77,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.234,-2.687,1.453,4.75777,0.039,H,A,0.52,-0.56,1.708,,64.34,OHH,-1.294,0.221079,0.00282362,0.950099 kka2_1:4_E169F,kka2_1:4_169,Kka2,kka2_1:4,P00552,0.950124,NO,169,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.996,-3.429,1.433,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.168804,0.00730086,0.950124 beta-lactamase_39_D252Q,beta-lactamase_39_252,TEM-1,beta-lactamase_39,P62593,0.950141,NO,252,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.0495842,0.00575769,0.950141 PSD95pdz3_N363L,PSD95pdz3_363,PSD95pdz3,PSD95pdz3,P31016,0.950177,NO,363,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-1.41,-3.265,1.855,5.23349,,,,,20.7037,,,,HPO,-1.29433,0.0758425,0.000524014,0.950177 kka2_1:8_A137P,kka2_1:8_137,Kka2,kka2_1:8,P00552,0.950193,NO,137,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.156,-4.148,1.992,,0.029,H,A,1.04,0.34,2.886,,63.26,PHB,-2.559,0.100394,0.00515054,0.950193 kka2_1:8_A137P,kka2_1:8_137,Kka2,kka2_1:8,P00552,0.950193,NO,137,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.156,-4.148,1.992,,0.029,H,A,1.04,0.34,2.886,,63.26,PHB,-2.559,0.100394,0.00515054,0.950193 kka2_1:8_R38M,kka2_1:8_38,Kka2,kka2_1:8,P00552,0.950212,NO,38,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.207,-3.078,1.871,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.100394,0.00372499,0.950212 kka2_1:8_R38M,kka2_1:8_38,Kka2,kka2_1:8,P00552,0.950212,NO,38,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.207,-3.078,1.871,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.100394,0.00372499,0.950212 hsp90_E590Y,hsp90_590,hsp90,hsp90,P02829,0.950224,NO,590,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.818,,,4.65049,0.021,H,A,,0.03,,,,HAO,-3.338,0.368192,0.000222939,0.950224 beta-lactamase_2500_E61I,beta-lactamase_2500_61,TEM-1,beta-lactamase_2500,P62593,0.950229,NO,61,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.115,-4.14,2.025,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.361275,0.00440955,0.950229 gb1_I232A,gb1_232,gb1,gb1,P06654,0.950239,NO,232,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-2.175,-2.787,0.612,,,,,,,0.766,,44.87,HHH,-2.152,0.177985,0.00580459,0.950239 beta-lactamase_2500_R239L,beta-lactamase_2500_239,TEM-1,beta-lactamase_2500,P62593,0.950244,NO,239,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.361275,0.00213852,0.950244 Pab1_T159R,Pab1_159,Pab1,Pab1,P04147,0.95027,NO,159,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.445,-3.649,2.204,,,,,,,2.531,,79.03,HPA,-1.19467,0.175299,0.00133849,0.95027 beta-lactamase_0_N134V,beta-lactamase_0_134,TEM-1,beta-lactamase_0,P62593,0.950273,NO,134,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-0.879,-3.751,2.872,,0.138,H,A,0.61,-0.6,3.776,,53.15,HPH,-1.02233,0.0500837,0.000644786,0.950273 beta-lactamase_0_R189K,beta-lactamase_0_189,TEM-1,beta-lactamase_0,P62593,0.950275,NO,189,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.844,-2.391,0.547,,0.278,H,A,1.2,1.01,12.11,12.11,72.73,HBB,-1.668,0.0500837,0.0050699,0.950275 kka2_1:2_G164D,kka2_1:2_164,Kka2,kka2_1:2,P00552,0.950291,NO,164,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.869,-2.664,1.795,,0.862,T,l,0.75,1.45,1.539,,64.39,POH,-1.828,0.295029,0.00442091,0.950291 beta-lactamase_A182D,beta-lactamase_182,TEM-1,beta-lactamase,P62593,0.950293,NO,182,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.777,-2.705,0.928,4.98609,0.136,H,A,0.52,-0.66,2.032,,93.01,OHH,-1.27367,0.221079,0.00559099,0.950293 beta-lactamase_E61I,beta-lactamase_61,TEM-1,beta-lactamase,P62593,0.950293,NO,61,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.115,-4.14,2.025,6.29701,0.775,T,a,0.52,1.29,1.975,,77.62,OAA,-1.92567,0.221079,0.00440955,0.950293 beta-lactamase_K284C,beta-lactamase_284,TEM-1,beta-lactamase,P62593,0.950293,NO,284,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.981,-5.143,3.162,6.30084,0.848,H,A,1.82,0.67,1.931,,77.62,HBB,-1.82133,0.221079,0.0686156,0.950293 beta-lactamase_R92Q,beta-lactamase_92,TEM-1,beta-lactamase,P62593,0.950293,NO,92,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.718,-3.029,1.311,5.65832,0.479,E,B,0.91,1.36,3.069,,65.38,BBH,-1.50367,0.221079,0.00429626,0.950293 beta-lactamase_39_E169Q,beta-lactamase_39_169,TEM-1,beta-lactamase_39,P62593,0.950348,NO,169,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.23,-2.523,1.293,,0.337,,A,1.04,1,15.633,15.633,73.08,PAH,-1.16533,0.0495842,0.00400994,0.950348 beta-lactamase_2500_F228M,beta-lactamase_2500_228,TEM-1,beta-lactamase_2500,P62593,0.950353,NO,228,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-2.342,-3.369,1.027,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.361275,0.0046669,0.950353 kka2_1:2_V49L,kka2_1:2_49,Kka2,kka2_1:2,P00552,0.950377,NO,49,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.614,-1.314,-0.3,,,E,B,0.44,-0.77,1.233,,64.39,HHB,-1.3,0.295029,0.00615685,0.950377 kka2_1:4_V84S,kka2_1:4_84,Kka2,kka2_1:4,P00552,0.950377,NO,84,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-2.279,-2.917,0.638,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.168804,0.00724019,0.950377 kka2_1:8_K175Y,kka2_1:8_175,Kka2,kka2_1:8,P00552,0.950403,NO,175,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-2.897,-3.379,0.482,,0.579,H,A,2.34,0.51,15.316,15.316,71.59,HBH,-1.82333,0.100394,0.00693093,0.950403 kka2_1:8_K175Y,kka2_1:8_175,Kka2,kka2_1:8,P00552,0.950403,NO,175,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-2.897,-3.379,0.482,,0.579,H,A,2.34,0.51,15.316,15.316,71.59,HBH,-1.82333,0.100394,0.00693093,0.950403 beta-lactamase_L160F,beta-lactamase_160,TEM-1,beta-lactamase,P62593,0.950416,NO,160,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.977,-3.681,2.704,5.32068,0.022,,B,1.75,-0.6,0.895,,44.41,BHA,-0.936,0.221079,0.00193775,0.950416 beta-lactamase_39_L199N,beta-lactamase_39_199,TEM-1,beta-lactamase_39,P62593,0.950439,NO,199,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-2.942,-3.124,0.182,,0.832,H,A,0.55,0.42,15.504,15.504,77.62,PHH,-2.32933,0.0495842,0.0048649,0.950439 beta-lactamase_2500_E175R,beta-lactamase_2500_175,TEM-1,beta-lactamase_2500,P62593,0.950454,NO,175,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.336,-3.064,0.728,,0.551,,A,1.04,1.05,5.316,,77.62,AAB,-1.31233,0.361275,0.00482205,0.950454 beta-lactamase_0_D271G,beta-lactamase_0_271,TEM-1,beta-lactamase_0,P62593,0.950459,NO,271,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.0500837,0.00752082,0.950459 beta-lactamase_39_D48L,beta-lactamase_39_48,TEM-1,beta-lactamase_39,P62593,0.950479,NO,48,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.101,-3.744,2.643,,0.189,E,B,0.75,0.21,0.735,,50.35,HAH,-1.62467,0.0495842,0.0027273,0.950479 beta-lactamase_625_E195W,beta-lactamase_625_195,TEM-1,beta-lactamase_625,P62593,0.950493,NO,195,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.186,-5.555,3.369,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.213352,0.00496565,0.950493 beta-lactamase_E46K,beta-lactamase_46,TEM-1,beta-lactamase,P62593,0.950502,NO,46,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.94,-3.66,1.72,5.36461,0.021,E,B,1.51,0.14,0.373,,59.44,HAH,-2.079,0.221079,0.00427568,0.950502 Pab1_A199T,Pab1_199,Pab1,Pab1,P04147,0.950562,NO,199,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.53,-3.31,1.78,,,,,,,1.479,,80.42,HHO,-1.50467,0.175299,0.00145024,0.950562 beta-lactamase_39_D83C,beta-lactamase_39_83,TEM-1,beta-lactamase_39,P62593,0.950602,NO,83,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.066,-5.147,4.081,,0.354,H,A,0.75,0.22,0.752,,48.95,HAH,-1.34733,0.0495842,0.00205968,0.950602 beta-lactamase_2500_I206K,beta-lactamase_2500_206,TEM-1,beta-lactamase_2500,P62593,0.950603,NO,206,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-2.429,-3.632,1.203,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.361275,0.00528934,0.950603 beta-lactamase_39_T69E,beta-lactamase_39_69,TEM-1,beta-lactamase_39,P62593,0.950616,NO,69,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-0.973,-3.476,2.503,,,G,A,0.22,-1.24,4.194,,93.01,PPH,-1.01833,0.0495842,0.00127498,0.950616 kka2_1:4_T72V,kka2_1:4_72,Kka2,kka2_1:4,P00552,0.950621,NO,72,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.38,-3.703,1.323,,0.784,H,A,0.82,0.29,6.463,,65.53,HPP,-2.238,0.168804,0.00750756,0.950621 beta-lactamase_2500_A124S,beta-lactamase_2500_124,TEM-1,beta-lactamase_2500,P62593,0.950638,NO,124,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.181,-3.066,1.885,,,H,A,0.46,-0.9,0.314,,64.34,HHH,-1.152,0.361275,0.00481399,0.950638 kka2_1:8_M120V,kka2_1:8_120,Kka2,kka2_1:8,P00552,0.950652,NO,120,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-3.877,-2.338,-1.539,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.100394,0.00265808,0.950652 kka2_1:8_M120V,kka2_1:8_120,Kka2,kka2_1:8,P00552,0.950652,NO,120,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-3.877,-2.338,-1.539,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.100394,0.00265808,0.950652 gb1_A252C,gb1_252,gb1,gb1,P06654,0.950677,NO,252,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.175,-4.148,2.973,,,,,,,,,,PHA,-1.55967,0.177985,0.00125598,0.950677 beta-lactamase_625_S122I,beta-lactamase_625_122,TEM-1,beta-lactamase_625,P62593,0.950703,NO,122,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.406,-3.138,0.732,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.213352,0.00497825,0.950703 Pab1_A182I,Pab1_182,Pab1,Pab1,P04147,0.950707,NO,182,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.013,-3.377,2.364,,,H,A,0.17,0.79,,,,AHH,-1.36067,0.175299,0.000289034,0.950707 beta-lactamase_0_P255R,beta-lactamase_0_255,TEM-1,beta-lactamase_0,P62593,0.950722,NO,255,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-2.266,-4.188,1.922,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.0500837,0.00499612,0.950722 kka2_1:8_P132L,kka2_1:8_132,Kka2,kka2_1:8,P00552,0.950728,NO,132,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.775,-3.61,2.835,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.100394,0.0018489,0.950728 kka2_1:8_P132L,kka2_1:8_132,Kka2,kka2_1:8,P00552,0.950728,NO,132,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.775,-3.61,2.835,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.100394,0.0018489,0.950728 beta-lactamase_39_I45W,beta-lactamase_39_45,TEM-1,beta-lactamase_39,P62593,0.950745,NO,45,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-2.421,-5.294,2.873,,,E,B,0.48,-0.3,2.256,,77.62,HHA,-2.30267,0.0495842,0.00452842,0.950745 kka2_1:4_C192G,kka2_1:4_192,Kka2,kka2_1:4,P00552,0.950751,NO,192,C,G,CG,Special,Special,5.07,3.29388,-1.77612,159,121,75,-46,108.5,60.1,-48.4,-1.067,-3.557,2.49,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.168804,0.00485428,0.950751 beta-lactamase_0_P143H,beta-lactamase_0_143,TEM-1,beta-lactamase_0,P62593,0.950752,NO,143,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.967,-4.789,3.822,,0.075,H,A,0.52,-0.37,11.868,11.868,66.78,OOB,-1.354,0.0500837,0.00114551,0.950752 beta-lactamase_0_A34Y,beta-lactamase_0_34,TEM-1,beta-lactamase_0,P62593,0.950763,NO,34,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.059,-4.077,2.018,,,H,A,0.46,-0.54,3.998,,73.78,AHA,-1.74967,0.0500837,0.00407913,0.950763 beta-lactamase_0_Y44T,beta-lactamase_0_44,TEM-1,beta-lactamase_0,P62593,0.950788,NO,44,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-2.547,-2.836,0.289,,,E,B,0.21,-0.45,1.751,,73.78,OHH,-1.86267,0.0500837,0.00426364,0.950788 beta-lactamase_S221L,beta-lactamase_221,TEM-1,beta-lactamase,P62593,0.950792,NO,221,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.754,-3.35,1.596,5.77407,0.624,H,A,0.74,-0.2,0.383,,74.48,BPH,-1.59967,0.221079,0.0046094,0.950792 kka2_1:4_E142W,kka2_1:4_142,Kka2,kka2_1:4,P00552,0.950796,NO,142,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.221,-5.578,3.357,,0.471,H,A,1.52,0.85,3.693,,65.53,HAB,-2.08033,0.168804,0.00748883,0.950796 beta-lactamase_2500_R239K,beta-lactamase_2500_239,TEM-1,beta-lactamase_2500,P62593,0.950834,NO,239,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.361275,0.00213852,0.950834 kka2_1:4_S204R,kka2_1:4_204,Kka2,kka2_1:4,P00552,0.950843,NO,204,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.353,-3.873,2.52,,0.144,E,A,0.27,-1.2,2.442,,65.53,HPO,-0.953333,0.168804,0.00881794,0.950843 beta-lactamase_0_R202W,beta-lactamase_0_202,TEM-1,beta-lactamase_0,P62593,0.950846,NO,202,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.292,-5.342,4.05,,0.188,H,A,1.2,0.62,7.016,,77.62,PBP,-1.54767,0.0500837,0.00321899,0.950846 kka2_1:8_V214Y,kka2_1:8_214,Kka2,kka2_1:8,P00552,0.950849,NO,214,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.261,-4.127,2.866,,0.117,E,B,1.48,-0.31,1.859,,64.39,OHH,-0.941667,0.100394,0.00692782,0.950849 kka2_1:8_V214Y,kka2_1:8_214,Kka2,kka2_1:8,P00552,0.950849,NO,214,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.261,-4.127,2.866,,0.117,E,B,1.48,-0.31,1.859,,64.39,OHH,-0.941667,0.100394,0.00692782,0.950849 beta-lactamase_39_G216C,beta-lactamase_39_216,TEM-1,beta-lactamase_39,P62593,0.950871,NO,216,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.477,-5.186,3.709,,0.437,I,A,0.29,-0.58,0.834,,74.48,HOO,-1.68067,0.0495842,0.00639568,0.950871 kka2_1:4_A71S,kka2_1:4_71,Kka2,kka2_1:4,P00552,0.950876,NO,71,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.824,-2.597,0.773,,0.553,H,A,0.46,0.08,5.76,,64.39,HHP,-1.74033,0.168804,0.00727707,0.950876 beta-lactamase_R238T,beta-lactamase_238,TEM-1,beta-lactamase,P62593,0.950888,NO,238,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.002,-2.871,0.869,5.87663,0.564,T,L,0.45,1.09,4.195,,72.73,ABO,-1.62633,0.221079,0.00743256,0.950888 beta-lactamase_P253L,beta-lactamase_253,TEM-1,beta-lactamase,P62593,0.950911,NO,253,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-2.253,-3.604,1.351,5.24842,0.308,,B,0.73,-0.46,2.293,,73.08,BOP,-2.10633,0.221079,0.00786358,0.950911 Pab1_A185D,Pab1_185,Pab1,Pab1,P04147,0.950914,NO,185,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.702,-3.262,1.56,,,,,,,1.756,,63.26,AHH,-1.66167,0.175299,0.00144499,0.950914 Pab1_S165L,Pab1_165,Pab1,Pab1,P04147,0.950918,NO,165,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.146,-3.175,2.029,,0.12,,a,,0.11,,,,BPB,-1.56867,0.175299,0.000307838,0.950918 PSD95pdz3_R318M,PSD95pdz3_318,PSD95pdz3,PSD95pdz3,P31016,0.950941,NO,318,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.582,-4.162,2.58,4.94876,,,,,17.5609,,,,BBO,-1.40567,0.0758425,0.00110471,0.950941 beta-lactamase_39_N152Y,beta-lactamase_39_152,TEM-1,beta-lactamase_39,P62593,0.950963,NO,152,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-2.757,-4.312,1.555,,0.863,H,A,0.61,0.92,4.038,,77.62,BPH,-2.97,0.0495842,0.00471429,0.950963 beta-lactamase_K284W,beta-lactamase_284,TEM-1,beta-lactamase,P62593,0.950972,NO,284,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.981,-5.384,3.403,6.30084,0.848,H,A,1.82,0.67,1.931,,77.62,HBB,-1.82133,0.221079,0.0686156,0.950972 beta-lactamase_L111Q,beta-lactamase_111,TEM-1,beta-lactamase,P62593,0.950972,NO,111,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.76,-3.108,1.348,5.8705,0.328,T,A,0.84,0.93,3.836,,64.34,BHP,-1.884,0.221079,0.00480671,0.950972 beta-lactamase_L111Y,beta-lactamase_111,TEM-1,beta-lactamase,P62593,0.950972,NO,111,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.76,-4.039,2.279,5.8705,0.328,T,A,0.84,0.93,3.836,,64.34,BHP,-1.884,0.221079,0.00480671,0.950972 beta-lactamase_V21S,beta-lactamase_21,TEM-1,beta-lactamase,P62593,0.950972,NO,21,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.873,-3.255,1.382,,,,,,,0.688,,93.01,OHH,-2.09633,0.221079,0.0028612,0.950972 beta-lactamase_R81R,beta-lactamase_81,TEM-1,beta-lactamase,P62593,0.950993,NO,81,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.466,-1.466,,5.12166,0.218,H,A,0.68,1.66,1.236,,50,PBH,-1.60667,0.221079,0.00499763,0.950993 beta-lactamase_2500_D36Y,beta-lactamase_2500_36,TEM-1,beta-lactamase_2500,P62593,0.950998,NO,36,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.732,-3.266,0.534,,0.555,H,A,0.75,1.17,2.26,,77.62,AAP,-1.91167,0.361275,0.00476483,0.950998 PSD95pdz3_E331V,PSD95pdz3_331,PSD95pdz3,PSD95pdz3,P31016,0.951019,NO,331,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.404,-3.21,1.806,5.86289,,,,,51.8889,,,,OAA,-1.22533,0.0758425,0.000950134,0.951019 beta-lactamase_2500_A222N,beta-lactamase_2500_222,TEM-1,beta-lactamase_2500,P62593,0.951033,NO,222,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.103,-3.751,1.648,,0.233,H,A,0.46,-0.25,0.379,,77.62,PHH,-1.63733,0.361275,0.00466094,0.951033 kka2_1:4_Q136H,kka2_1:4_136,Kka2,kka2_1:4,P00552,0.951047,NO,136,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-3.021,-3.255,0.234,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.168804,0.00624149,0.951047 beta-lactamase_0_E61G,beta-lactamase_0_61,TEM-1,beta-lactamase_0,P62593,0.95108,NO,61,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.115,-2.393,0.278,,0.775,T,a,1.04,1.29,34.763,34.763,77.62,OAA,-1.92567,0.0500837,0.00440955,0.95108 gb1_T242V,gb1_242,gb1,gb1,P06654,0.951113,NO,242,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.245,-2.814,1.569,,,,,,,,,,APP,-1.444,0.177985,0.00243886,0.951113 beta-lactamase_625_R91D,beta-lactamase_625_91,TEM-1,beta-lactamase_625,P62593,0.951116,NO,91,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.392,-3.521,2.129,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.213352,0.00380226,0.951116 Pab1_N139M,Pab1_139,Pab1,Pab1,P04147,0.951148,NO,139,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-1.079,-4.522,3.443,,0.062,H,A,,-0.73,,,,APB,-1.09667,0.175299,0.000339145,0.951148 beta-lactamase_2500_G85S,beta-lactamase_2500_85,TEM-1,beta-lactamase_2500,P62593,0.951176,NO,85,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.011,-3.264,2.253,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.361275,0.00252173,0.951176 kka2_1:2_A71S,kka2_1:2_71,Kka2,kka2_1:2,P00552,0.951185,NO,71,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.824,-2.597,0.773,,0.553,H,A,0.46,0.08,9.788,,64.39,HHP,-1.74033,0.295029,0.00727707,0.951185 kka2_1:8_D5Y,kka2_1:8_5,Kka2,kka2_1:8,P00552,0.951205,NO,5,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.306,-4.118,2.812,,,,,,,1.147,,71.59,PAO,-1.784,0.100394,0.00222864,0.951205 kka2_1:8_D5Y,kka2_1:8_5,Kka2,kka2_1:8,P00552,0.951205,NO,5,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.306,-4.118,2.812,,,,,,,1.147,,71.59,PAO,-1.784,0.100394,0.00222864,0.951205 beta-lactamase_0_E175V,beta-lactamase_0_175,TEM-1,beta-lactamase_0,P62593,0.951267,NO,175,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.336,-2.38,0.044,,0.551,,A,1.04,1.05,2.334,,77.62,AAB,-1.31233,0.0500837,0.00482205,0.951267 kka2_1:2_G55H,kka2_1:2_55,Kka2,kka2_1:2,P00552,0.951271,NO,55,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.625,-2.922,1.297,,0.517,S,b,0.75,1.19,15.753,15.753,63.64,POH,-2.05967,0.295029,0.00667877,0.951271 PSD95pdz3_L367I,PSD95pdz3_367,PSD95pdz3,PSD95pdz3,P31016,0.951278,NO,367,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.347,-2.567,1.22,5.47696,,,,,17.0063,,,,AHB,-1.39767,0.0758425,0.000466436,0.951278 kka2_1:8_R38C,kka2_1:8_38,Kka2,kka2_1:8,P00552,0.951281,NO,38,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.207,-4.996,3.789,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.100394,0.00372499,0.951281 kka2_1:8_R38C,kka2_1:8_38,Kka2,kka2_1:8,P00552,0.951281,NO,38,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.207,-4.996,3.789,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.100394,0.00372499,0.951281 beta-lactamase_39_D48N,beta-lactamase_39_48,TEM-1,beta-lactamase_39,P62593,0.951282,NO,48,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.101,-3.389,2.288,,0.189,E,B,0.75,0.21,0.735,,50.35,HAH,-1.62467,0.0495842,0.0027273,0.951282 beta-lactamase_625_R176I,beta-lactamase_625_176,TEM-1,beta-lactamase_625,P62593,0.951296,NO,176,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-0.863,-4.01,3.147,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.213352,0.00105554,0.951296 PSD95pdz3_F340V,PSD95pdz3_340,PSD95pdz3,PSD95pdz3,P31016,0.951311,NO,340,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.524,-2.985,1.461,5.79283,,,,,11.8045,,,,PHH,-1.55767,0.0758425,0.000836987,0.951311 beta-lactamase_2500_A225F,beta-lactamase_2500_225,TEM-1,beta-lactamase_2500,P62593,0.951319,NO,225,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.845,-4.402,2.557,,1,T,B,0.46,-0.38,0.551,,74.48,OHO,-1.39967,0.361275,0.00465057,0.951319 kka2_1:8_L107M,kka2_1:8_107,Kka2,kka2_1:8,P00552,0.951319,NO,107,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.238,-2.856,1.618,,0.197,.,B,0.55,-1.1,4.478,,71.59,BHH,-2.143,0.100394,0.00561937,0.951319 kka2_1:8_L107M,kka2_1:8_107,Kka2,kka2_1:8,P00552,0.951319,NO,107,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.238,-2.856,1.618,,0.197,.,B,0.55,-1.1,4.478,,71.59,BHH,-2.143,0.100394,0.00561937,0.951319 beta-lactamase_39_L120M,beta-lactamase_39_120,TEM-1,beta-lactamase_39,P62593,0.951328,NO,120,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.044,-4.046,3.002,,,H,A,0.55,-1.13,22.254,22.254,64.69,AHO,-1.13633,0.0495842,0.00143563,0.951328 Pab1_L153S,Pab1_153,Pab1,Pab1,P04147,0.951345,NO,153,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.039,-3.428,2.389,,0.46,E,A,,-0.95,,,,HHP,-1.17667,0.175299,0.000321212,0.951345 E1_Ubiquitin_A46E,E1_Ubiquitin_46,Uba1,E1_Ubiquitin,P0CG63,0.95137,NO,46,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.367,-3.441,2.074,,0.398,T,L,,-0.8,,,,HHO,-1.17167,0.18783,0.004233,0.95137 E1_Ubiquitin_A46L,E1_Ubiquitin_46,Uba1,E1_Ubiquitin,P0CG63,0.95137,NO,46,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.367,-2.261,0.894,,0.398,T,L,,-0.8,,,,HHO,-1.17167,0.18783,0.004233,0.95137 E1_Ubiquitin_G47Y,E1_Ubiquitin_47,Uba1,E1_Ubiquitin,P0CG63,0.95137,NO,47,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.999,-4.128,3.129,,0.057,T,l,,-1.21,,,,HOB,-1.195,0.18783,0.00142261,0.95137 E1_Ubiquitin_Q40N,E1_Ubiquitin_40,Uba1,E1_Ubiquitin,P0CG63,0.95137,NO,40,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-1.48,-3.313,1.833,,0.387,G,A,,0.03,,,,OPP,-1.365,0.18783,0.0037961,0.95137 beta-lactamase_F149Y,beta-lactamase_149,TEM-1,beta-lactamase,P62593,0.951379,NO,149,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.299,-1.705,0.406,5.54789,0.195,H,A,1.1,0.11,1.863,,63.99,HHH,-1.46067,0.221079,0.00418462,0.951379 beta-lactamase_R118I,beta-lactamase_118,TEM-1,beta-lactamase,P62593,0.951379,NO,118,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.413,-3.968,1.555,5.8227,0.457,H,A,0.68,1.39,2.144,,77.62,HBA,-1.785,0.221079,0.00538794,0.951379 beta-lactamase_2500_D33G,beta-lactamase_2500_33,TEM-1,beta-lactamase_2500,P62593,0.951404,NO,33,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.321,-3.465,1.144,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.361275,0.00435556,0.951404 Pab1_I196C,Pab1_196,Pab1,Pab1,P04147,0.951416,NO,196,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.795,-4.53,2.735,,,,,,,2.013,,80.59,AHH,-1.44667,0.175299,0.0016933,0.951416 beta-lactamase_39_E62T,beta-lactamase_39_62,TEM-1,beta-lactamase_39,P62593,0.951424,NO,62,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.193,-3.522,2.329,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.0495842,0.00264802,0.951424 beta-lactamase_625_P105Y,beta-lactamase_625_105,TEM-1,beta-lactamase_625,P62593,0.951429,NO,105,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.813,-4.385,3.572,,0.226,T,A,0.52,0.8,1.154,,63.29,POH,-1.01533,0.213352,0.0011981,0.951429 beta-lactamase_R202A,beta-lactamase_202,TEM-1,beta-lactamase,P62593,0.951431,NO,202,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.292,-2.462,1.17,5.16273,0.188,H,A,0.68,0.62,1.918,,77.62,PBP,-1.54767,0.221079,0.00321899,0.951431 Pab1_L191R,Pab1_191,Pab1,Pab1,P04147,0.951439,NO,191,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.2,-3.747,2.547,,0.204,E,B,,2.24,,,,HHP,-1.20133,0.175299,0.000583797,0.951439 kka2_1:4_L57M,kka2_1:4_57,Kka2,kka2_1:4,P00552,0.951444,NO,57,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.898,-4.404,2.506,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.168804,0.00723769,0.951444 beta-lactamase_39_T147N,beta-lactamase_39_147,TEM-1,beta-lactamase_39,P62593,0.951454,NO,147,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.149,-2.415,1.266,,0.281,H,A,0.22,-0.68,13.843,13.843,64.34,HPH,-1.456,0.0495842,0.00226017,0.951454 PSD95pdz3_L342Q,PSD95pdz3_342,PSD95pdz3,PSD95pdz3,P31016,0.951455,NO,342,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.347,-3.806,2.459,5.03015,,,,,12.0762,,,,HHH,-1.428,0.0758425,0.00081112,0.951455 kka2_1:1_N195D,kka2_1:1_195,Kka2,kka2_1:1,P00552,0.951456,NO,195,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-0.836,-2.379,1.543,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.520039,0.00276134,0.951456 kka2_1:4_R44F,kka2_1:4_44,Kka2,kka2_1:4,P00552,0.95146,NO,44,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.062,-4.405,2.343,,0.487,S,B,1.2,-0.35,5.71,,71.59,OBO,-1.80767,0.168804,0.00745043,0.95146 Pab1_N132C,Pab1_132,Pab1,Pab1,P04147,0.95147,NO,132,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-1.079,-4.904,3.825,,0.412,S,l,,0.9,,,,BPH,-1.067,0.175299,0.000347671,0.95147 beta-lactamase_156_V31S,beta-lactamase_156_31,TEM-1,beta-lactamase_156,P62593,0.951488,NO,31,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.822,-3.594,1.772,,,H,A,0.44,-0.46,4.126,,73.78,BHB,-2.03767,0.111618,0.00478065,0.951488 kka2_1:4_T72W,kka2_1:4_72,Kka2,kka2_1:4,P00552,0.951491,NO,72,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.38,-5.516,3.136,,0.784,H,A,0.82,0.29,6.463,,65.53,HPP,-2.238,0.168804,0.00750756,0.951491 beta-lactamase_2500_M127E,beta-lactamase_2500_127,TEM-1,beta-lactamase_2500,P62593,0.951492,NO,127,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-2.251,-3.04,0.789,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.361275,0.00437927,0.951492 beta-lactamase_39_G52I,beta-lactamase_39_52,TEM-1,beta-lactamase_39,P62593,0.951514,NO,52,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.149,-4.163,3.014,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.0495842,0.00340138,0.951514 beta-lactamase_A77S,beta-lactamase_77,TEM-1,beta-lactamase,P62593,0.951527,NO,77,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.234,-2.62,1.386,4.75777,0.039,H,A,0.52,-0.56,1.708,,64.34,OHH,-1.294,0.221079,0.00282362,0.951527 beta-lactamase_F22N,beta-lactamase_22,TEM-1,beta-lactamase,P62593,0.951527,NO,22,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-2.676,-3.854,1.178,,,,,,,1.616,,73.08,HHH,-2.03233,0.221079,0.00262842,0.951527 beta-lactamase_R273I,beta-lactamase_273,TEM-1,beta-lactamase,P62593,0.951527,NO,273,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.314,-4.08,1.766,,0.564,H,A,1.2,1.57,,,73.78,ABP,-1.841,0.221079,0.0077952,0.951527 beta-lactamase_R7N,beta-lactamase_7,TEM-1,beta-lactamase,P62593,0.951527,NO,7,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.683,-3.677,1.994,,,,,,,2.44,,67.13,HBH,-1.96267,0.221079,0.00211375,0.951527 beta-lactamase_T198M,beta-lactamase_198,TEM-1,beta-lactamase,P62593,0.951527,NO,198,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.168,-4.608,2.44,4.9209,0.489,,B,0.69,-0.13,0.37,,73.78,HPH,-1.98767,0.221079,0.004311,0.951527 beta-lactamase_39_R257Y,beta-lactamase_39_257,TEM-1,beta-lactamase_39,P62593,0.951548,NO,257,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.0495842,0.00756629,0.951548 gb1_T237S,gb1_237,gb1,gb1,P06654,0.951549,NO,237,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.736,-2.835,1.099,,,,,,,0.218,,11.83,BPH,-2.27833,0.177985,0.00275316,0.951549 kka2_1:2_L93M,kka2_1:2_93,Kka2,kka2_1:2,P00552,0.951558,NO,93,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.815,-3.907,3.092,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.295029,0.00131498,0.951558 Ubiquitin_A28G,Ubiquitin_28,Uba1,Ubiquitin,P0CG48,0.951613,NO,28,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.895,-2.731,0.836,4.73736,0.369,H,A,,-0.11,,,,BHB,-1.47667,0.205827,0.000842053,0.951613 Ubiquitin_A28R,Ubiquitin_28,Uba1,Ubiquitin,P0CG48,0.951613,NO,28,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.895,-3.002,1.107,4.73736,0.369,H,A,,-0.11,,,,BHB,-1.47667,0.205827,0.000842053,0.951613 Ubiquitin_A28V,Ubiquitin_28,Uba1,Ubiquitin,P0CG48,0.951613,NO,28,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.895,-2.843,0.948,4.73736,0.369,H,A,,-0.11,,,,BHB,-1.47667,0.205827,0.000842053,0.951613 Ubiquitin_A46T,Ubiquitin_46,Uba1,Ubiquitin,P0CG48,0.951613,NO,46,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.77,-3.513,1.743,5.38761,0.398,T,L,2.34,-0.8,6.506,,51.09,HHO,-1.505,0.205827,0.000581142,0.951613 Ubiquitin_D21L,Ubiquitin_21,Uba1,Ubiquitin,P0CG48,0.951613,NO,21,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.193,-3.647,2.454,4.96432,0.165,,B,0.23,-0.53,1.013,,71.82,PAP,-1.35867,0.205827,0.000465257,0.951613 Ubiquitin_D21W,Ubiquitin_21,Uba1,Ubiquitin,P0CG48,0.951613,NO,21,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.193,-5.316,4.123,4.96432,0.165,,B,0.23,-0.53,1.013,,71.82,PAP,-1.35867,0.205827,0.000465257,0.951613 Ubiquitin_D24I,Ubiquitin_24,Uba1,Ubiquitin,P0CG48,0.951613,NO,24,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,,,,,,,,,,,,,HAP,,0.205827,0.0066591,0.951613 Ubiquitin_D24M,Ubiquitin_24,Uba1,Ubiquitin,P0CG48,0.951613,NO,24,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,,,,,,,,,,,,,HAP,,0.205827,0.0066591,0.951613 Ubiquitin_D39I,Ubiquitin_39,Uba1,Ubiquitin,P0CG48,0.951613,NO,39,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.792,-3.064,1.272,5.1607,0.433,G,A,,0.55,,,,OAP,-1.754,0.205827,0.00071409,0.951613 Ubiquitin_D58N,Ubiquitin_58,Uba1,Ubiquitin,P0CG48,0.951613,NO,58,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.622,-2.607,0.985,5.06391,0.457,G,A,,-0.54,,,,PAH,-1.60267,0.205827,0.000639847,0.951613 Ubiquitin_D58T,Ubiquitin_58,Uba1,Ubiquitin,P0CG48,0.951613,NO,58,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.622,-3.526,1.904,5.06391,0.457,G,A,,-0.54,,,,PAH,-1.60267,0.205827,0.000639847,0.951613 Ubiquitin_E18W,Ubiquitin_18,Uba1,Ubiquitin,P0CG48,0.951613,NO,18,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.696,-5.479,3.783,5.04795,0.545,,B,,0.03,,,,HAO,-1.78733,0.205827,0.000623342,0.951613 Ubiquitin_E51L,Ubiquitin_51,Uba1,Ubiquitin,P0CG48,0.951613,NO,51,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.534,-3.544,2.01,5.36711,0.545,,B,,0.72,,,,HAA,-1.357,0.205827,0.000868134,0.951613 Ubiquitin_E64Y,Ubiquitin_64,Uba1,Ubiquitin,P0CG48,0.951613,NO,64,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.763,-4.218,2.455,5.084,0.54,T,l,,0.79,,,,BAP,-1.64433,0.205827,0.000817406,0.951613 Ubiquitin_F45I,Ubiquitin_45,Uba1,Ubiquitin,P0CG48,0.951613,NO,45,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.322,-2.613,1.291,4.80693,0.26,E,B,1.62,-0.99,1.531,,53.87,HHH,-1.55267,0.205827,0.000470401,0.951613 Ubiquitin_F45T,Ubiquitin_45,Uba1,Ubiquitin,P0CG48,0.951613,NO,45,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.322,-2.675,1.353,4.80693,0.26,E,B,1.62,-0.99,1.531,,53.87,HHH,-1.55267,0.205827,0.000470401,0.951613 Ubiquitin_F45V,Ubiquitin_45,Uba1,Ubiquitin,P0CG48,0.951613,NO,45,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.322,-3.162,1.84,4.80693,0.26,E,B,1.62,-0.99,1.531,,53.87,HHH,-1.55267,0.205827,0.000470401,0.951613 Ubiquitin_F4M,Ubiquitin_4,Uba1,Ubiquitin,P0CG48,0.951613,NO,4,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.534,-4.355,2.821,4.77459,0.059,E,B,,-0.46,,,,HHH,-1.504,0.205827,0.000805043,0.951613 Ubiquitin_K11A,Ubiquitin_11,Uba1,Ubiquitin,P0CG48,0.951613,NO,11,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.354,-3.173,1.819,5.16813,0.401,,B,2.81,0.84,0.335,,25.84,OBP,-1.346,0.205827,0.000535553,0.951613 Ubiquitin_K11N,Ubiquitin_11,Uba1,Ubiquitin,P0CG48,0.951613,NO,11,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.354,-2.599,1.245,5.16813,0.401,,B,2.81,0.84,0.335,,25.84,OBP,-1.346,0.205827,0.000535553,0.951613 Ubiquitin_K63A,Ubiquitin_63,Uba1,Ubiquitin,P0CG48,0.951613,NO,63,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.635,-2.642,1.007,5.08297,0.721,T,B,,0.59,,,,PBA,-1.74467,0.205827,0.000607964,0.951613 Ubiquitin_K63G,Ubiquitin_63,Uba1,Ubiquitin,P0CG48,0.951613,NO,63,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.635,-3.355,1.72,5.08297,0.721,T,B,,0.59,,,,PBA,-1.74467,0.205827,0.000607964,0.951613 Ubiquitin_K63I,Ubiquitin_63,Uba1,Ubiquitin,P0CG48,0.951613,NO,63,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.635,-4.114,2.479,5.08297,0.721,T,B,,0.59,,,,PBA,-1.74467,0.205827,0.000607964,0.951613 Ubiquitin_K63S,Ubiquitin_63,Uba1,Ubiquitin,P0CG48,0.951613,NO,63,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.635,-2.693,1.058,5.08297,0.721,T,B,,0.59,,,,PBA,-1.74467,0.205827,0.000607964,0.951613 Ubiquitin_K63V,Ubiquitin_63,Uba1,Ubiquitin,P0CG48,0.951613,NO,63,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.635,-3.726,2.091,5.08297,0.721,T,B,,0.59,,,,PBA,-1.74467,0.205827,0.000607964,0.951613 Ubiquitin_K6R,Ubiquitin_6,Uba1,Ubiquitin,P0CG48,0.951613,NO,6,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.093,-2.403,1.31,4.84211,0.35,E,B,1.82,-0.62,1.502,,71.82,HBP,-1.36133,0.205827,0.000784795,0.951613 Ubiquitin_L50I,Ubiquitin_50,Uba1,Ubiquitin,P0CG48,0.951613,NO,50,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.107,-3.094,1.987,5.19399,0.029,,B,,-0.92,,,,PHA,-1.52733,0.205827,0.000734242,0.951613 Ubiquitin_N25L,Ubiquitin_25,Uba1,Ubiquitin,P0CG48,0.951613,NO,25,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-1.95,-3.465,1.515,4.76563,0.444,H,A,0.09,0,2.3,,31.09,APH,-1.741,0.205827,0.00071919,0.951613 Ubiquitin_N60T,Ubiquitin_60,Uba1,Ubiquitin,P0CG48,0.951613,NO,60,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-1.775,-2.813,1.038,5.00332,0.775,T,L,,0.33,,,,HPH,-1.532,0.205827,0.000814061,0.951613 Ubiquitin_N60V,Ubiquitin_60,Uba1,Ubiquitin,P0CG48,0.951613,NO,60,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-1.775,-2.904,1.129,5.00332,0.775,T,L,,0.33,,,,HPH,-1.532,0.205827,0.000814061,0.951613 Ubiquitin_P19W,Ubiquitin_19,Uba1,Ubiquitin,P0CG48,0.951613,NO,19,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-2.352,-3.015,0.663,4.67617,0.398,T,A,,-0.61,,,,AOP,-1.86233,0.205827,0.000729653,0.951613 Ubiquitin_Q31F,Ubiquitin_31,Uba1,Ubiquitin,P0CG48,0.951613,NO,31,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-1.678,-4.204,2.526,4.5004,0.464,H,A,,0.68,,,,HPA,-1.44467,0.205827,0.000724141,0.951613 Ubiquitin_Q40S,Ubiquitin_40,Uba1,Ubiquitin,P0CG48,0.951613,NO,40,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-1.752,-2.74,0.988,4.7807,0.387,G,A,,0.03,,,,APP,-1.62433,0.205827,0.000619089,0.951613 Ubiquitin_S65R,Ubiquitin_65,Uba1,Ubiquitin,P0CG48,0.951613,NO,65,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.535,-2.969,1.434,4.99442,0.168,,b,0.25,-0.68,16.756,16.756,33.87,APP,-1.626,0.205827,0.000546776,0.951613 Ubiquitin_T22A,Ubiquitin_22,Uba1,Ubiquitin,P0CG48,0.951613,NO,22,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.344,-2.933,1.589,4.54389,0.237,B,B,,-0.75,,,,APH,-1.28733,0.205827,0.000535592,0.951613 Ubiquitin_T22I,Ubiquitin_22,Uba1,Ubiquitin,P0CG48,0.951613,NO,22,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.344,-2.721,1.377,4.54389,0.237,B,B,,-0.75,,,,APH,-1.28733,0.205827,0.000535592,0.951613 Ubiquitin_T22R,Ubiquitin_22,Uba1,Ubiquitin,P0CG48,0.951613,NO,22,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.344,-2.72,1.376,4.54389,0.237,B,B,,-0.75,,,,APH,-1.28733,0.205827,0.000535592,0.951613 Ubiquitin_T22S,Ubiquitin_22,Uba1,Ubiquitin,P0CG48,0.951613,NO,22,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.344,-2.054,0.71,4.54389,0.237,B,B,,-0.75,,,,APH,-1.28733,0.205827,0.000535592,0.951613 Ubiquitin_T66D,Ubiquitin_66,Uba1,Ubiquitin,P0CG48,0.951613,NO,66,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.58,-3.731,2.151,5.02702,0.46,E,B,0.8,-0.81,28.36,28.36,39.71,PPH,-1.51667,0.205827,0.000598414,0.951613 Ubiquitin_V17F,Ubiquitin_17,Uba1,Ubiquitin,P0CG48,0.951613,NO,17,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.314,-2.825,1.511,5.26282,0.017,,B,2.78,-0.77,3.239,,71.82,AHA,-1.51833,0.205827,0.000659638,0.951613 Ubiquitin_V26T,Ubiquitin_26,Uba1,Ubiquitin,P0CG48,0.951613,NO,26,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.321,-3.356,2.035,4.78447,,H,A,,-0.97,,,,PHB,-1.445,0.205827,0.000980269,0.951613 Ubiquitin_V5L,Ubiquitin_5,Uba1,Ubiquitin,P0CG48,0.951613,NO,5,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.576,-2.126,0.55,4.75677,,E,B,,-0.82,,,,HHB,-1.401,0.205827,0.000796998,0.951613 beta-lactamase_39_M184N,beta-lactamase_39_184,TEM-1,beta-lactamase_39,P62593,0.951623,NO,184,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.593,-4.028,2.435,,,H,A,0.55,-0.87,2.893,,62.94,HHH,-1.41,0.0495842,0.00356019,0.951623 Pab1_K180A,Pab1_180,Pab1,Pab1,P04147,0.951633,NO,180,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.945,-3.116,1.171,,,,,,,,,,HBA,-1.575,0.175299,0.00295933,0.951633 beta-lactamase_2500_L135M,beta-lactamase_2500_135,TEM-1,beta-lactamase_2500,P62593,0.951667,NO,135,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.002,-2.838,1.836,,0.117,H,A,0.55,-0.58,0.795,,43.71,PHH,-1.03767,0.361275,0.00244423,0.951667 beta-lactamase_D99S,beta-lactamase_99,TEM-1,beta-lactamase,P62593,0.951672,NO,99,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.191,-3.286,2.095,5.66081,0.402,G,A,0.23,0.36,1.318,,64.69,PAH,-1.794,0.221079,0.00305446,0.951672 beta-lactamase_P20H,beta-lactamase_20,TEM-1,beta-lactamase,P62593,0.951672,NO,20,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.74,-4.695,2.955,,,,,,,0.368,,67.83,HOH,-1.765,0.221079,0.00235322,0.951672 kka2_1:2_V49A,kka2_1:2_49,Kka2,kka2_1:2,P00552,0.951699,NO,49,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.614,-2.584,0.97,,,E,B,0.44,-0.77,1.233,,64.39,HHB,-1.3,0.295029,0.00615685,0.951699 kka2_1:4_G74C,kka2_1:4_74,Kka2,kka2_1:4,P00552,0.9517,NO,74,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.18,-5.237,4.057,,0.621,T,l,0.75,0.2,1.032,,64.39,POH,-1.91667,0.168804,0.00587035,0.9517 beta-lactamase_625_M184C,beta-lactamase_625_184,TEM-1,beta-lactamase_625,P62593,0.951701,NO,184,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.593,-4.787,3.194,,,H,A,0.55,-0.87,2.765,,62.94,HHH,-1.41,0.213352,0.00356019,0.951701 beta-lactamase_2500_L160M,beta-lactamase_2500_160,TEM-1,beta-lactamase_2500,P62593,0.951722,NO,160,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.977,-3.902,2.925,,0.022,,B,0.55,-0.6,0.895,,44.41,BHA,-0.936,0.361275,0.00193775,0.951722 kka2_1:1_D52E,kka2_1:1_52,Kka2,kka2_1:1,P00552,0.951747,NO,52,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.271,-0.829,-1.442,,0.22,E,B,0.75,0.8,2.64,,71.59,PAH,-2.38367,0.520039,0.00175694,0.951747 beta-lactamase_2500_P172D,beta-lactamase_2500_172,TEM-1,beta-lactamase_2500,P62593,0.951782,NO,172,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.998,-3.578,2.58,,0.639,T,b,0.52,0.24,4.99,,74.48,HOP,-2.03067,0.361275,0.00312594,0.951782 beta-lactamase_39_D33K,beta-lactamase_39_33,TEM-1,beta-lactamase_39,P62593,0.951782,NO,33,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.321,-3.459,1.138,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.0495842,0.00435556,0.951782 beta-lactamase_2500_Q203L,beta-lactamase_2500_203,TEM-1,beta-lactamase_2500,P62593,0.951792,NO,203,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.168,-2.697,0.529,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.361275,0.00631514,0.951792 beta-lactamase_0_Q203C,beta-lactamase_0_203,TEM-1,beta-lactamase_0,P62593,0.951795,NO,203,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.168,-5.086,2.918,,0.47,H,A,0.64,-0.38,14.541,14.541,65.38,BPP,-1.614,0.0500837,0.00631514,0.951795 beta-lactamase_39_A225I,beta-lactamase_39_225,TEM-1,beta-lactamase_39,P62593,0.951796,NO,225,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.845,-4.041,2.196,,1,T,B,0.46,-0.38,9.874,9.874,74.48,OHO,-1.39967,0.0495842,0.00465057,0.951796 beta-lactamase_0_P25R,beta-lactamase_0_25,TEM-1,beta-lactamase_0,P62593,0.9518,NO,25,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.526,-3.8,2.274,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.0500837,0.00347571,0.9518 beta-lactamase_2500_R63K,beta-lactamase_2500_63,TEM-1,beta-lactamase_2500,P62593,0.951817,NO,63,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-0.943,-2.877,1.934,,0.218,,B,1.2,-0.31,0.929,,44.06,ABH,-0.992333,0.361275,0.00126938,0.951817 kka2_1:8_Y22L,kka2_1:8_22,Kka2,kka2_1:8,P00552,0.951833,NO,22,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-1.583,-3.408,1.825,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.100394,0.00598977,0.951833 kka2_1:8_Y22L,kka2_1:8_22,Kka2,kka2_1:8,P00552,0.951833,NO,22,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-1.583,-3.408,1.825,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.100394,0.00598977,0.951833 beta-lactamase_156_Y262I,beta-lactamase_156_262,TEM-1,beta-lactamase_156,P62593,0.951842,NO,262,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.111618,0.00853516,0.951842 beta-lactamase_0_G90T,beta-lactamase_0_90,TEM-1,beta-lactamase_0,P62593,0.951892,NO,90,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-2.091,-2.913,0.822,,0.598,T,A,0.29,0.32,2.04,,77.62,HOB,-1.52633,0.0500837,0.00490273,0.951892 beta-lactamase_E210S,beta-lactamase_210,TEM-1,beta-lactamase,P62593,0.951892,NO,210,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.319,-2.669,0.35,5.7398,0.476,H,A,0.52,0.75,1.555,,77.62,HAH,-1.88567,0.221079,0.00663582,0.951892 beta-lactamase_0_R242S,beta-lactamase_0_242,TEM-1,beta-lactamase_0,P62593,0.951905,NO,242,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.0500837,0.00452879,0.951905 beta-lactamase_0_V82S,beta-lactamase_0_82,TEM-1,beta-lactamase_0,P62593,0.951907,NO,82,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.325,-3.501,2.176,,0.267,H,A,0.44,0.08,1.893,,93.01,BHA,-1.28567,0.0500837,0.00397046,0.951907 Pab1_I128T,Pab1_128,Pab1,Pab1,P04147,0.951915,NO,128,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.345,-3.235,1.89,,0.008,E,B,1.68,-0.6,1.706,,78.68,PHH,-1.231,0.175299,0.00104192,0.951915 Pab1_G188A,Pab1_188,Pab1,Pab1,P04147,0.951925,NO,188,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.809,-2.67,1.861,,0.379,E,g,,2.18,,,,POH,-1.14633,0.175299,0.000280911,0.951925 beta-lactamase_2500_R273C,beta-lactamase_2500_273,TEM-1,beta-lactamase_2500,P62593,0.951957,NO,273,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.314,-5.09,2.776,,0.564,H,A,1.2,1.57,19.943,19.943,73.78,ABP,-1.841,0.361275,0.0077952,0.951957 beta-lactamase_39_M115R,beta-lactamase_39_115,TEM-1,beta-lactamase_39,P62593,0.951978,NO,115,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.389,-2.862,1.473,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.0495842,0.0034337,0.951978 beta-lactamase_39_K213L,beta-lactamase_39_213,TEM-1,beta-lactamase_39,P62593,0.951997,NO,213,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.81,-3.558,1.748,,0.67,,A,2.34,0.29,2.648,,67.83,ABH,-1.57767,0.0495842,0.00610411,0.951997 beta-lactamase_0_G90A,beta-lactamase_0_90,TEM-1,beta-lactamase_0,P62593,0.952,NO,90,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-2.091,-2.713,0.622,,0.598,T,A,0.29,0.32,2.04,,77.62,HOB,-1.52633,0.0500837,0.00490273,0.952 beta-lactamase_2500_R189V,beta-lactamase_2500_189,TEM-1,beta-lactamase_2500,P62593,0.952006,NO,189,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.844,-3.783,1.939,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.361275,0.0050699,0.952006 beta-lactamase_39_D212M,beta-lactamase_39_212,TEM-1,beta-lactamase_39,P62593,0.952006,NO,212,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.624,-4.83,3.206,,0.037,,b,0.75,-0.58,10.748,10.748,74.48,HAB,-1.77667,0.0495842,0.00644302,0.952006 beta-lactamase_Q265C,beta-lactamase_265,TEM-1,beta-lactamase,P62593,0.952049,NO,265,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.58,-5.191,2.611,6.62674,1.116,,A,0.03,1.17,12.514,12.514,69.58,PPH,-1.978,0.221079,0.00811926,0.952049 beta-lactamase_T261S,beta-lactamase_261,TEM-1,beta-lactamase,P62593,0.952049,NO,261,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.88,-2.94,0.06,5.65483,0.014,E,B,0.53,-0.39,2.449,,77.62,HPP,-1.771,0.221079,0.0123091,0.952049 beta-lactamase_156_Q97I,beta-lactamase_156_97,TEM-1,beta-lactamase_156,P62593,0.952086,NO,97,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.072,-4.072,2,,0.823,G,A,0.64,2.42,4.457,,77.62,PPP,-2.43833,0.111618,0.0045116,0.952086 beta-lactamase_T198L,beta-lactamase_198,TEM-1,beta-lactamase,P62593,0.952119,NO,198,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.168,-3.433,1.265,4.9209,0.489,,B,0.69,-0.13,0.37,,73.78,HPH,-1.98767,0.221079,0.004311,0.952119 Pab1_A178N,Pab1_178,Pab1,Pab1,P04147,0.952126,NO,178,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.579,-3.513,1.934,,0.019,H,A,0.64,0.64,2.7,,81.63,OHH,-1.61067,0.175299,0.00160192,0.952126 kka2_1:2_L60R,kka2_1:2_60,Kka2,kka2_1:2,P00552,0.95213,NO,60,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.997,-4.088,3.091,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.295029,0.00262176,0.95213 beta-lactamase_39_V101W,beta-lactamase_39_101,TEM-1,beta-lactamase_39,P62593,0.952161,NO,101,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.295,-5.385,4.09,,0.342,,B,0.44,0,2.96,,73.08,HHA,-1.54367,0.0495842,0.00374492,0.952161 beta-lactamase_P25K,beta-lactamase_25,TEM-1,beta-lactamase,P62593,0.952193,NO,25,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.526,-3.426,1.9,5.6134,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.221079,0.00347571,0.952193 kka2_1:8_G99Q,kka2_1:8_99,Kka2,kka2_1:8,P00552,0.952195,NO,99,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.596,-4.153,3.557,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.100394,0.00186055,0.952195 kka2_1:8_G99Q,kka2_1:8_99,Kka2,kka2_1:8,P00552,0.952195,NO,99,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.596,-4.153,3.557,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.100394,0.00186055,0.952195 PSD95pdz3_S350F,PSD95pdz3_350,PSD95pdz3,PSD95pdz3,P31016,0.952198,NO,350,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.519,-3.749,2.23,4.97629,,,,,25.01,,,,HPO,-1.29133,0.0758425,0.000704883,0.952198 gb1_D266E,gb1_266,gb1,gb1,P06654,0.9522,NO,266,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.261,-2.791,1.53,,,,,,,0.638,,45.54,HAO,-1.59333,0.177985,0.00394694,0.9522 kka2_1:1_Q4W,kka2_1:1_4,Kka2,kka2_1:1,P00552,0.952212,NO,4,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.361,-5.167,2.806,,,,,,,5.615,,71.59,APA,-1.95533,0.520039,0.00239179,0.952212 beta-lactamase_625_L100C,beta-lactamase_625_100,TEM-1,beta-lactamase_625,P62593,0.952232,NO,100,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.218,-4.758,3.54,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.213352,0.00413885,0.952232 beta-lactamase_2500_D99A,beta-lactamase_2500_99,TEM-1,beta-lactamase_2500,P62593,0.95224,NO,99,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.191,-2.613,1.422,,0.402,G,A,0.75,0.36,1.318,,64.69,PAH,-1.794,0.361275,0.00305446,0.95224 kka2_1:1_M116R,kka2_1:1_116,Kka2,kka2_1:1,P00552,0.952251,NO,116,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-2.482,-4.144,1.662,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.520039,0.00745147,0.952251 kka2_1:8_L184I,kka2_1:8_184,Kka2,kka2_1:8,P00552,0.952252,NO,184,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.496,-2.585,1.089,,0.489,E,B,0.55,-0.06,4.495,,63.26,AHH,-1.24833,0.100394,0.00518742,0.952252 kka2_1:8_L184I,kka2_1:8_184,Kka2,kka2_1:8,P00552,0.952252,NO,184,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.496,-2.585,1.089,,0.489,E,B,0.55,-0.06,4.495,,63.26,AHH,-1.24833,0.100394,0.00518742,0.952252 PSD95pdz3_G345H,PSD95pdz3_345,PSD95pdz3,PSD95pdz3,P31016,0.952273,NO,345,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.008,-4.362,3.354,4.32868,,,,,13.165,,,,OOO,-1.084,0.0758425,0.000771806,0.952273 beta-lactamase_625_D161C,beta-lactamase_625_161,TEM-1,beta-lactamase_625,P62593,0.952274,NO,161,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.891,-5.1,4.209,,0.341,,A,0.75,-0.52,4.655,,61.19,HAB,-0.961333,0.213352,0.000897697,0.952274 beta-lactamase_39_D33C,beta-lactamase_39_33,TEM-1,beta-lactamase_39,P62593,0.952283,NO,33,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.321,-5.054,2.733,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.0495842,0.00435556,0.952283 beta-lactamase_F6N,beta-lactamase_6,TEM-1,beta-lactamase,P62593,0.952299,NO,6,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.847,-4.081,2.234,,,,,,,1.276,,67.83,BHB,-2.076,0.221079,0.00261627,0.952299 beta-lactamase_2500_V82C,beta-lactamase_2500_82,TEM-1,beta-lactamase_2500,P62593,0.952305,NO,82,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.325,-4.774,3.449,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.361275,0.00397046,0.952305 kka2_1:2_R239L,kka2_1:2_239,Kka2,kka2_1:2,P00552,0.952312,NO,239,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.949,-2.571,-0.378,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.295029,0.00835326,0.952312 beta-lactamase_0_L47E,beta-lactamase_0_47,TEM-1,beta-lactamase_0,P62593,0.952337,NO,47,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.876,-2.999,1.123,,0.007,E,B,0.55,0.2,1.024,,67.83,AHA,-1.639,0.0500837,0.00439844,0.952337 beta-lactamase_39_L284I,beta-lactamase_39_284,TEM-1,beta-lactamase_39,P62593,0.952345,NO,284,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.0495842,0.0686156,0.952345 beta-lactamase_2500_D33Y,beta-lactamase_2500_33,TEM-1,beta-lactamase_2500,P62593,0.952353,NO,33,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.321,-4.331,2.01,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.361275,0.00435556,0.952353 Pab1_A141V,Pab1_141,Pab1,Pab1,P04147,0.952381,NO,141,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.461,-3.075,1.614,,0.34,H,A,0.52,-0.27,2.15,,79.03,BHH,-1.19433,0.175299,0.00165974,0.952381 beta-lactamase_0_E169H,beta-lactamase_0_169,TEM-1,beta-lactamase_0,P62593,0.952392,NO,169,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.23,-4.45,3.22,,0.337,,A,1.04,1,3.516,,73.08,PAH,-1.16533,0.0500837,0.00400994,0.952392 beta-lactamase_156_G249N,beta-lactamase_156_249,TEM-1,beta-lactamase_156,P62593,0.952397,NO,249,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.111618,0.00220169,0.952397 beta-lactamase_L205I,beta-lactamase_205,TEM-1,beta-lactamase,P62593,0.952446,NO,205,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.922,-2.97,2.048,5.67023,,H,A,1.3,-0.46,0.678,,42.31,PHH,-1.57767,0.221079,0.00255802,0.952446 beta-lactamase_P60L,beta-lactamase_60,TEM-1,beta-lactamase,P62593,0.952462,NO,60,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-2.469,-2.818,0.349,5.51353,0.256,T,A,0.73,-0.56,3.653,,77.62,BOA,-1.97633,0.221079,0.00521318,0.952462 beta-lactamase_T267L,beta-lactamase_267,TEM-1,beta-lactamase,P62593,0.952468,NO,267,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.308,-3.548,1.24,5.28263,0.54,,B,0.69,-0.14,0.374,,73.78,HPH,-1.9,0.221079,0.0102128,0.952468 beta-lactamase_39_D33Y,beta-lactamase_39_33,TEM-1,beta-lactamase_39,P62593,0.952469,NO,33,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.321,-4.331,2.01,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.0495842,0.00435556,0.952469 beta-lactamase_2500_G226R,beta-lactamase_2500_226,TEM-1,beta-lactamase_2500,P62593,0.952475,NO,226,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.461,-3.022,1.561,,0.701,T,l,0.29,-0.25,5.086,,74.48,HOH,-1.42933,0.361275,0.00665294,0.952475 kka2_1:4_T225I,kka2_1:4_225,Kka2,kka2_1:4,P00552,0.952479,NO,225,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.393,-3.64,1.247,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.168804,0.0113598,0.952479 beta-lactamase_2500_H110S,beta-lactamase_2500_110,TEM-1,beta-lactamase_2500,P62593,0.952514,NO,110,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-1.706,-3.537,1.831,,0.341,G,a,0.17,1.08,31.31,31.31,64.69,BBH,-1.73333,0.361275,0.00441499,0.952514 beta-lactamase_G226E,beta-lactamase_226,TEM-1,beta-lactamase,P62593,0.952521,NO,226,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.461,-2.776,1.315,5.70682,0.701,T,l,0.77,-0.25,3.199,,74.48,HOH,-1.42933,0.221079,0.00665294,0.952521 beta-lactamase_0_L28Y,beta-lactamase_0_28,TEM-1,beta-lactamase_0,P62593,0.952529,NO,28,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.579,-4.094,2.515,,0.277,H,A,0.55,-0.16,9.35,9.35,93.01,PHH,-2.11333,0.0500837,0.00359321,0.952529 beta-lactamase_L135M,beta-lactamase_135,TEM-1,beta-lactamase,P62593,0.952542,NO,135,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.002,-2.838,1.836,5.28497,0.117,H,A,1.07,-0.58,0.697,,43.71,PHH,-1.03767,0.221079,0.00244423,0.952542 beta-lactamase_2500_H287S,beta-lactamase_2500_287,TEM-1,beta-lactamase_2500,P62593,0.952544,NO,287,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,,,,,,,,,,,,,BBH,-1.111,0.361275,,0.952544 beta-lactamase_39_Q203A,beta-lactamase_39_203,TEM-1,beta-lactamase_39,P62593,0.952561,NO,203,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.168,-2.117,-0.051,,0.47,H,A,0.64,-0.38,1.453,,65.38,BPP,-1.614,0.0495842,0.00631514,0.952561 kka2_1:2_A191M,kka2_1:2_191,Kka2,kka2_1:2,P00552,0.952562,NO,191,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.831,-4.572,3.741,,,.,b,0.46,-0.94,2.046,,50,AHO,-0.868667,0.295029,0.00338807,0.952562 kka2_1:4_L243I,kka2_1:4_243,Kka2,kka2_1:4,P00552,0.952567,NO,243,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-2.651,-3.227,0.576,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.168804,0.00884927,0.952567 beta-lactamase_I229V,beta-lactamase_229,TEM-1,beta-lactamase,P62593,0.952572,NO,229,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.267,-1.684,0.417,5.0911,0.083,E,B,1,-0.76,1.114,,50,HHH,-1.58767,0.221079,0.00477249,0.952572 kka2_1:2_S32G,kka2_1:2_32,Kka2,kka2_1:2,P00552,0.952588,NO,32,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-0.804,-2.936,2.132,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.295029,0.00149998,0.952588 beta-lactamase_2500_G216Q,beta-lactamase_2500_216,TEM-1,beta-lactamase_2500,P62593,0.952597,NO,216,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.477,-3.862,2.385,,0.437,I,A,0.29,-0.58,1.983,,74.48,HOO,-1.68067,0.361275,0.00639568,0.952597 PSD95pdz3_R368V,PSD95pdz3_368,PSD95pdz3,PSD95pdz3,P31016,0.9526,NO,368,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.582,-3.435,1.853,6.13355,,,,,18.1818,,,,HBP,-1.50033,0.0758425,0.000451517,0.9526 beta-lactamase_2500_P25S,beta-lactamase_2500_25,TEM-1,beta-lactamase_2500,P62593,0.952609,NO,25,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.526,-3.274,1.748,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.361275,0.00347571,0.952609 Pab1_G188N,Pab1_188,Pab1,Pab1,P04147,0.952613,NO,188,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.809,-3.265,2.456,,0.379,E,g,,2.18,,,,POH,-1.14633,0.175299,0.000280911,0.952613 beta-lactamase_156_D48R,beta-lactamase_156_48,TEM-1,beta-lactamase_156,P62593,0.952626,NO,48,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.101,-3.84,2.739,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.111618,0.0027273,0.952626 gb1_K230S,gb1_230,gb1,gb1,P06654,0.952632,NO,230,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.701,-3.172,1.471,,,,,,,0.166,,11.83,HBH,-1.52867,0.177985,0.00331703,0.952632 gb1_N234M,gb1_234,gb1,gb1,P06654,0.952632,NO,234,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-2.055,-4.379,2.324,,,,,,,1.235,,45.54,HPO,-2.05067,0.177985,0.00242189,0.952632 Pab1_H134R,Pab1_134,Pab1,Pab1,P04147,0.952632,NO,134,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-1.542,-3.517,1.975,,,,,,,,,,HBO,-1.346,0.175299,0.00116356,0.952632 kka2_1:4_P109K,kka2_1:4_109,Kka2,kka2_1:4,P00552,0.952672,NO,109,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.412,-3.629,2.217,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.168804,0.0070929,0.952672 beta-lactamase_2500_V157L,beta-lactamase_2500_157,TEM-1,beta-lactamase_2500,P62593,0.952696,NO,157,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.751,-3.066,1.315,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.361275,0.00506849,0.952696 beta-lactamase_39_A268W,beta-lactamase_39_268,TEM-1,beta-lactamase_39,P62593,0.95271,NO,268,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.0495842,0.0102525,0.95271 beta-lactamase_A276V,beta-lactamase_276,TEM-1,beta-lactamase,P62593,0.952731,NO,276,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.144,-3.192,2.048,5.1387,0.117,H,A,0.52,-0.84,1.283,,44.06,HHA,-1.47,0.221079,0.0191712,0.952731 beta-lactamase_39_M115Q,beta-lactamase_39_115,TEM-1,beta-lactamase_39,P62593,0.952763,NO,115,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.389,-3.893,2.504,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.0495842,0.0034337,0.952763 beta-lactamase_39_T139A,beta-lactamase_39_139,TEM-1,beta-lactamase_39,P62593,0.95278,NO,139,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.901,-2.031,0.13,,0.216,H,A,0.22,0.39,0.421,,77.62,PPH,-2.04667,0.0495842,0.00441837,0.95278 beta-lactamase_0_P143V,beta-lactamase_0_143,TEM-1,beta-lactamase_0,P62593,0.952781,NO,143,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.967,-3.311,2.344,,0.075,H,A,0.52,-0.37,11.868,11.868,66.78,OOB,-1.354,0.0500837,0.00114551,0.952781 beta-lactamase_39_V101F,beta-lactamase_39_101,TEM-1,beta-lactamase_39,P62593,0.952781,NO,101,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.295,-3.936,2.641,,0.342,,B,0.44,0,2.96,,73.08,HHA,-1.54367,0.0495842,0.00374492,0.952781 kka2_1:4_A35E,kka2_1:4_35,Kka2,kka2_1:4,P00552,0.952788,NO,35,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.127,-2.492,0.365,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.168804,0.00630016,0.952788 PSD95pdz3_A370W,PSD95pdz3_370,PSD95pdz3,PSD95pdz3,P31016,0.952795,NO,370,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.307,-5.004,3.697,5.22304,,,,,17.284,,,,PHP,-1.57967,0.0758425,0.000429106,0.952795 kka2_1:2_G74P,kka2_1:2_74,Kka2,kka2_1:2,P00552,0.952801,NO,74,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.18,-3.953,2.773,,0.621,T,l,0.75,0.2,1.446,,64.39,POH,-1.91667,0.295029,0.00587035,0.952801 Pab1_I196T,Pab1_196,Pab1,Pab1,P04147,0.952812,NO,196,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.795,-3.157,1.362,,,,,,,2.013,,80.59,AHH,-1.44667,0.175299,0.0016933,0.952812 beta-lactamase_0_G43S,beta-lactamase_0_43,TEM-1,beta-lactamase_0,P62593,0.952824,NO,43,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.62,-3.161,2.541,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.0500837,0.00120151,0.952824 gb1_D266G,gb1_266,gb1,gb1,P06654,0.952848,NO,266,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.261,-3.083,1.822,,,,,,,0.638,,45.54,HAO,-1.59333,0.177985,0.00394694,0.952848 beta-lactamase_0_P65N,beta-lactamase_0_65,TEM-1,beta-lactamase_0,P62593,0.952868,NO,65,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.894,-3.952,3.058,,0.098,E,B,0.52,-0.62,0.663,,40.56,HOH,-1.03233,0.0500837,0.00152776,0.952868 Pab1_K164L,Pab1_164,Pab1,Pab1,P04147,0.952883,NO,164,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-2.298,-3.271,0.973,,,,,,,,,,OBP,-1.41767,0.175299,0.00255241,0.952883 beta-lactamase_2500_S122F,beta-lactamase_2500_122,TEM-1,beta-lactamase_2500,P62593,0.952931,NO,122,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.406,-3.279,0.873,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.361275,0.00497825,0.952931 kka2_1:8_R89N,kka2_1:8_89,Kka2,kka2_1:8,P00552,0.952935,NO,89,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.548,-3.002,1.454,,0.209,E,B,1.2,1.41,25.3,25.3,64.39,OBA,-1.89867,0.100394,0.00524373,0.952935 kka2_1:8_R89N,kka2_1:8_89,Kka2,kka2_1:8,P00552,0.952935,NO,89,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.548,-3.002,1.454,,0.209,E,B,1.2,1.41,25.3,25.3,64.39,OBA,-1.89867,0.100394,0.00524373,0.952935 beta-lactamase_156_S122M,beta-lactamase_156_122,TEM-1,beta-lactamase_156,P62593,0.953006,NO,122,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.406,-4.704,2.298,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.111618,0.00497825,0.953006 beta-lactamase_E270H,beta-lactamase_270,TEM-1,beta-lactamase,P62593,0.953008,NO,270,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.723,-4.611,2.888,5.33196,0.422,H,A,0.52,1.15,1.745,,64.34,AAB,-1.70933,0.221079,0.00767762,0.953008 beta-lactamase_Q97N,beta-lactamase_97,TEM-1,beta-lactamase,P62593,0.953008,NO,97,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.072,-3.773,1.701,6.30204,0.823,G,A,1.1,2.42,1.157,,77.62,PPP,-2.43833,0.221079,0.0045116,0.953008 beta-lactamase_V29S,beta-lactamase_29,TEM-1,beta-lactamase,P62593,0.953008,NO,29,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-2.856,-2.693,-0.163,5.58481,0.733,H,A,0.23,-0.78,1.287,,93.01,HHB,-2.24733,0.221079,0.00318969,0.953008 Pab1_V198M,Pab1_198,Pab1,Pab1,P04147,0.953016,NO,198,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.113,-3.847,2.734,,0.008,E,B,0.61,0.91,,,,HHH,-1.32933,0.175299,0.000268557,0.953016 kka2_1:4_A14E,kka2_1:4_14,Kka2,kka2_1:4,P00552,0.953023,NO,14,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.837,-3.519,1.682,,0.728,G,A,0.46,0.7,0.36,,71.59,HHH,-1.82567,0.168804,0.00706614,0.953023 hsp90_N588S,hsp90_588,hsp90,hsp90,P02829,0.953041,NO,588,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-3.051,-2.764,0,4.61142,0.019,H,A,0.14,0.39,,,,HPH,-3.12167,0.368192,0.000222939,0.953041 beta-lactamase_39_D271V,beta-lactamase_39_271,TEM-1,beta-lactamase_39,P62593,0.953043,NO,271,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.0495842,0.00752082,0.953043 kka2_1:1_Q252E,kka2_1:1_252,Kka2,kka2_1:1,P00552,0.953051,NO,252,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.63,-1.971,-0.659,,0.906,H,A,0.64,0.35,1.369,,92.05,PPB,-2.20733,0.520039,0.0121001,0.953051 beta-lactamase_156_L49E,beta-lactamase_156_49,TEM-1,beta-lactamase_156,P62593,0.953062,NO,49,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.897,-3.608,1.711,,0.131,T,A,0.55,0.04,3.112,,64.69,AHP,-1.99233,0.111618,0.00401477,0.953062 beta-lactamase_L223A,beta-lactamase_223,TEM-1,beta-lactamase,P62593,0.953063,NO,223,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.055,-3.102,2.047,5.42318,0.27,,B,1.3,0.09,1.511,,74.48,HHO,-1.35033,0.221079,0.00372793,0.953063 gb1_V247D,gb1_247,gb1,gb1,P06654,0.953064,NO,247,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.711,-3.591,1.88,,,,,,,0.805,,44.87,HHA,-1.485,0.177985,0.00435373,0.953064 beta-lactamase_39_T69N,beta-lactamase_39_69,TEM-1,beta-lactamase_39,P62593,0.953072,NO,69,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-0.973,-3.537,2.564,,,G,A,0.22,-1.24,4.194,,93.01,PPH,-1.01833,0.0495842,0.00127498,0.953072 beta-lactamase_2500_R273I,beta-lactamase_2500_273,TEM-1,beta-lactamase_2500,P62593,0.953073,NO,273,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.314,-4.08,1.766,,0.564,H,A,1.2,1.57,19.943,19.943,73.78,ABP,-1.841,0.361275,0.0077952,0.953073 beta-lactamase_625_E62K,beta-lactamase_625_62,TEM-1,beta-lactamase_625,P62593,0.953082,NO,62,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.193,-3.246,2.053,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.213352,0.00264802,0.953082 beta-lactamase_0_G234F,beta-lactamase_0_234,TEM-1,beta-lactamase_0,P62593,0.953086,NO,234,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.62,-4.292,3.672,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.0500837,0.000889577,0.953086 beta-lactamase_2500_S256I,beta-lactamase_2500_256,TEM-1,beta-lactamase_2500,P62593,0.953113,NO,256,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.621,-3.676,2.055,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.361275,0.00710634,0.953113 beta-lactamase_156_G216E,beta-lactamase_156_216,TEM-1,beta-lactamase_156,P62593,0.953119,NO,216,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.477,-2.451,0.974,,0.437,I,A,0.29,-0.58,12.464,12.464,74.48,HOO,-1.68067,0.111618,0.00639568,0.953119 beta-lactamase_39_D33V,beta-lactamase_39_33,TEM-1,beta-lactamase_39,P62593,0.953129,NO,33,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.321,-3.488,1.167,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.0495842,0.00435556,0.953129 kka2_1:4_F206L,kka2_1:4_206,Kka2,kka2_1:4,P00552,0.95313,NO,206,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.349,-2.335,0.986,,0.006,E,B,0.58,-1.21,1.342,,63.64,OHH,-1.04,0.168804,0.00936868,0.95313 kka2_1:8_G164P,kka2_1:8_164,Kka2,kka2_1:8,P00552,0.953143,NO,164,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.869,-3.944,3.075,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.100394,0.00442091,0.953143 kka2_1:8_G164P,kka2_1:8_164,Kka2,kka2_1:8,P00552,0.953143,NO,164,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.869,-3.944,3.075,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.100394,0.00442091,0.953143 beta-lactamase_2500_E26C,beta-lactamase_2500_26,TEM-1,beta-lactamase_2500,P62593,0.95317,NO,26,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.454,-5.02,2.566,,0.54,H,A,1.04,0.98,0.49,,93.01,OAP,-1.96167,0.361275,0.00297948,0.95317 beta-lactamase_0_G90P,beta-lactamase_0_90,TEM-1,beta-lactamase_0,P62593,0.953181,NO,90,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-2.091,-3.952,1.861,,0.598,T,A,0.29,0.32,2.04,,77.62,HOB,-1.52633,0.0500837,0.00490273,0.953181 beta-lactamase_2500_W163V,beta-lactamase_2500_163,TEM-1,beta-lactamase_2500,P62593,0.953191,NO,163,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-1.843,-3.617,1.774,,0.467,,B,0.47,-0.5,32.624,32.624,63.99,BHA,-1.269,0.361275,0.00418955,0.953191 beta-lactamase_625_G154M,beta-lactamase_625_154,TEM-1,beta-lactamase_625,P62593,0.953205,NO,154,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.823,-4.936,4.113,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.213352,0.00180205,0.953205 beta-lactamase_39_G216R,beta-lactamase_39_216,TEM-1,beta-lactamase_39,P62593,0.953213,NO,216,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.477,-2.93,1.453,,0.437,I,A,0.29,-0.58,0.834,,74.48,HOO,-1.68067,0.0495842,0.00639568,0.953213 beta-lactamase_2500_E210D,beta-lactamase_2500_210,TEM-1,beta-lactamase_2500,P62593,0.953215,NO,210,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.319,-3.702,1.383,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.361275,0.00663582,0.953215 Pab1_L191Y,Pab1_191,Pab1,Pab1,P04147,0.953289,NO,191,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.2,-3.83,2.63,,0.204,E,B,,2.24,,,,HHP,-1.20133,0.175299,0.000583797,0.953289 kka2_1:8_W24L,kka2_1:8_24,Kka2,kka2_1:8,P00552,0.953295,NO,24,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-1.779,-2.533,0.754,,0.477,E,B,1.51,-0.21,2.503,,56.06,AHH,-2.24467,0.100394,0.00631564,0.953295 kka2_1:8_W24L,kka2_1:8_24,Kka2,kka2_1:8,P00552,0.953295,NO,24,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-1.779,-2.533,0.754,,0.477,E,B,1.51,-0.21,2.503,,56.06,AHH,-2.24467,0.100394,0.00631564,0.953295 PSD95pdz3_T385F,PSD95pdz3_385,PSD95pdz3,PSD95pdz3,P31016,0.953301,NO,385,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.533,-3.844,2.311,5.57157,,,,,23.6871,4.527,,87.71,PPH,-1.56567,0.0758425,0.000545119,0.953301 beta-lactamase_625_T264G,beta-lactamase_625_264,TEM-1,beta-lactamase_625,P62593,0.953305,NO,264,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.213352,0.0119399,0.953305 beta-lactamase_2500_A133S,beta-lactamase_2500_133,TEM-1,beta-lactamase_2500,P62593,0.953311,NO,133,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.186,-3.092,1.906,,,H,A,0.46,-0.86,2.649,,67.83,HHP,-0.988333,0.361275,0.00468022,0.953311 beta-lactamase_2500_G39M,beta-lactamase_2500_39,TEM-1,beta-lactamase_2500,P62593,0.953321,NO,39,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.864,-4.879,3.015,,0.701,T,L,0.29,0.47,29.926,29.926,77.62,HOH,-1.53633,0.361275,0.00487611,0.953321 beta-lactamase_A183I,beta-lactamase_183,TEM-1,beta-lactamase,P62593,0.953321,NO,183,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.231,-2.835,1.604,4.84712,0.155,H,A,0.55,-0.91,12.189,,77.62,HHH,-1.53367,0.221079,0.00296631,0.953321 PSD95pdz3_A376Y,PSD95pdz3_376,PSD95pdz3,PSD95pdz3,P31016,0.953322,NO,376,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.307,-3.844,2.537,4.72134,,,,,17.108,,,,HHH,-1.49567,0.0758425,0.000341232,0.953322 beta-lactamase_156_G90W,beta-lactamase_156_90,TEM-1,beta-lactamase_156,P62593,0.953338,NO,90,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-2.091,-5.515,3.424,,0.598,T,A,0.29,0.32,0.319,,77.62,HOB,-1.52633,0.111618,0.00490273,0.953338 beta-lactamase_0_P217I,beta-lactamase_0_217,TEM-1,beta-lactamase_0,P62593,0.953351,NO,217,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-2.062,-4.071,2.009,,0.496,I,A,0.52,-0.33,1.087,,74.48,OOH,-1.64333,0.0500837,0.00463211,0.953351 beta-lactamase_39_V42Y,beta-lactamase_39_42,TEM-1,beta-lactamase_39,P62593,0.95337,NO,42,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.564,-4.12,2.556,,0.017,E,B,0.44,-0.51,1.86,,63.99,BHO,-1.042,0.0495842,0.00404515,0.95337 beta-lactamase_0_E26P,beta-lactamase_0_26,TEM-1,beta-lactamase_0,P62593,0.953373,NO,26,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.454,-2.862,0.408,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.0500837,0.00297948,0.953373 beta-lactamase_0_N168C,beta-lactamase_0_168,TEM-1,beta-lactamase_0,P62593,0.953384,NO,168,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-1.029,-4.99,3.961,,0.113,G,A,0.61,-0.4,0.881,,44.41,HPA,-1.13233,0.0500837,0.00288667,0.953384 beta-lactamase_39_D48R,beta-lactamase_39_48,TEM-1,beta-lactamase_39,P62593,0.953397,NO,48,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.101,-3.84,2.739,,0.189,E,B,0.75,0.21,0.735,,50.35,HAH,-1.62467,0.0495842,0.0027273,0.953397 beta-lactamase_2500_R41K,beta-lactamase_2500_41,TEM-1,beta-lactamase_2500,P62593,0.953409,NO,41,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-0.942,-2.85,1.908,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.361275,0.00123327,0.953409 beta-lactamase_39_D36A,beta-lactamase_39_36,TEM-1,beta-lactamase_39,P62593,0.953415,NO,36,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.732,-2.434,-0.298,,0.555,H,A,0.75,1.17,13.689,13.689,77.62,AAP,-1.91167,0.0495842,0.00476483,0.953415 beta-lactamase_G85A,beta-lactamase_85,TEM-1,beta-lactamase,P62593,0.953421,NO,85,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.011,-3.043,2.032,5.58951,0.805,T,l,0.23,1.7,1.468,,63.64,HOP,-1.68733,0.221079,0.00252173,0.953421 beta-lactamase_2500_S266A,beta-lactamase_2500_266,TEM-1,beta-lactamase_2500,P62593,0.953427,NO,266,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.369,-2.686,1.317,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.361275,0.0140785,0.953427 kka2_1:1_E59Q,kka2_1:1_59,Kka2,kka2_1:1,P00552,0.953434,NO,59,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-0.952,-2.672,1.72,,0.187,.,L,1.04,0.62,2.648,,50.38,PAH,-1.53,0.520039,0.00280355,0.953434 beta-lactamase_0_P172L,beta-lactamase_0_172,TEM-1,beta-lactamase_0,P62593,0.953442,NO,172,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.998,-2.658,1.66,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.0500837,0.00312594,0.953442 beta-lactamase_39_D252P,beta-lactamase_39_252,TEM-1,beta-lactamase_39,P62593,0.953465,NO,252,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.0495842,0.00575769,0.953465 beta-lactamase_R189L,beta-lactamase_189,TEM-1,beta-lactamase,P62593,0.953478,NO,189,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.844,-3.611,1.767,5.74877,0.278,H,A,0.68,1.01,1.512,,72.73,HBB,-1.668,0.221079,0.0050699,0.953478 beta-lactamase_2500_H287R,beta-lactamase_2500_287,TEM-1,beta-lactamase_2500,P62593,0.953479,NO,287,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,,,,,,,,,,,,,BBH,-1.111,0.361275,,0.953479 beta-lactamase_2500_E272Y,beta-lactamase_2500_272,TEM-1,beta-lactamase_2500,P62593,0.953481,NO,272,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.361275,0.00545371,0.953481 beta-lactamase_A133S,beta-lactamase_133,TEM-1,beta-lactamase,P62593,0.953501,NO,133,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.186,-3.092,1.906,4.86423,,H,A,0.55,-0.86,2.649,,67.83,HHP,-0.988333,0.221079,0.00468022,0.953501 beta-lactamase_R7R,beta-lactamase_7,TEM-1,beta-lactamase,P62593,0.953533,NO,7,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.683,-1.683,,,,,,,,2.44,,67.13,HBH,-1.96267,0.221079,0.00211375,0.953533 kka2_1:2_E111M,kka2_1:2_111,Kka2,kka2_1:2,P00552,0.953575,NO,111,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.28,-4.788,2.508,,0.155,H,A,1.52,-1.14,2.792,,65.53,HAB,-2.27833,0.295029,0.00746789,0.953575 beta-lactamase_V82A,beta-lactamase_82,TEM-1,beta-lactamase,P62593,0.953589,NO,82,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.325,-2.13,0.805,5.27777,0.267,H,A,0.96,0.08,1.379,,93.01,BHA,-1.28567,0.221079,0.00397046,0.953589 beta-lactamase_0_S256R,beta-lactamase_0_256,TEM-1,beta-lactamase_0,P62593,0.953592,NO,256,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.0500837,0.00710634,0.953592 hsp90_N588R,hsp90_588,hsp90,hsp90,P02829,0.953605,NO,588,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-3.051,-3.086,0,4.61142,0.019,H,A,0.14,0.39,,,,HPH,-3.12167,0.368192,0.000222939,0.953605 beta-lactamase_39_D252N,beta-lactamase_39_252,TEM-1,beta-lactamase_39,P62593,0.953635,NO,252,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.0495842,0.00575769,0.953635 beta-lactamase_R92S,beta-lactamase_92,TEM-1,beta-lactamase,P62593,0.953638,NO,92,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.718,-3.47,1.752,5.65832,0.479,E,B,0.91,1.36,3.069,,65.38,BBH,-1.50367,0.221079,0.00429626,0.953638 beta-lactamase_39_G142K,beta-lactamase_39_142,TEM-1,beta-lactamase_39,P62593,0.953644,NO,142,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.707,-3.645,2.938,,0.034,,p,0.29,-0.64,1.947,,64.69,OOO,-0.834,0.0495842,0.00060149,0.953644 beta-lactamase_2500_H110M,beta-lactamase_2500_110,TEM-1,beta-lactamase_2500,P62593,0.953656,NO,110,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-1.706,-3.324,1.618,,0.341,G,a,0.17,1.08,31.31,31.31,64.69,BBH,-1.73333,0.361275,0.00441499,0.953656 beta-lactamase_K213F,beta-lactamase_213,TEM-1,beta-lactamase,P62593,0.953659,NO,213,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.81,-4.437,2.627,5.63167,0.67,,A,1.59,0.29,3.924,,67.83,ABH,-1.57767,0.221079,0.00610411,0.953659 kka2_1:2_D250S,kka2_1:2_250,Kka2,kka2_1:2,P00552,0.953659,NO,250,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.015,-2.641,1.626,,0.274,.,b,0.75,-0.46,3.796,,51.89,OAP,-1.83933,0.295029,0.0177103,0.953659 beta-lactamase_156_E87K,beta-lactamase_156_87,TEM-1,beta-lactamase_156,P62593,0.953697,NO,87,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.421,-2.715,1.294,,0.048,,B,1.04,0.92,1.754,,64.69,PAP,-1.969,0.111618,0.00337888,0.953697 beta-lactamase_2500_I125M,beta-lactamase_2500_125,TEM-1,beta-lactamase_2500,P62593,0.953702,NO,125,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.441,-2.597,1.156,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.361275,0.00383964,0.953702 beta-lactamase_2500_P217M,beta-lactamase_2500_217,TEM-1,beta-lactamase_2500,P62593,0.953741,NO,217,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-2.062,-4.835,2.773,,0.496,I,A,0.52,-0.33,0.431,,74.48,OOH,-1.64333,0.361275,0.00463211,0.953741 beta-lactamase_0_E169A,beta-lactamase_0_169,TEM-1,beta-lactamase_0,P62593,0.953767,NO,169,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.23,-2.486,1.256,,0.337,,A,1.04,1,3.516,,73.08,PAH,-1.16533,0.0500837,0.00400994,0.953767 beta-lactamase_2500_L146V,beta-lactamase_2500_146,TEM-1,beta-lactamase_2500,P62593,0.953787,NO,146,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.462,-1.839,0.377,,0.007,H,A,0.55,-0.56,1.578,,64.69,AHP,-1.656,0.361275,0.00474542,0.953787 kka2_1:8_H124P,kka2_1:8_124,Kka2,kka2_1:8,P00552,0.953787,NO,124,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-0.84,-3.908,3.068,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.100394,0.00211296,0.953787 kka2_1:8_H124P,kka2_1:8_124,Kka2,kka2_1:8,P00552,0.953787,NO,124,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-0.84,-3.908,3.068,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.100394,0.00211296,0.953787 beta-lactamase_39_Q88I,beta-lactamase_39_88,TEM-1,beta-lactamase_39,P62593,0.953791,NO,88,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.086,-3.166,1.08,,0.807,,B,0.64,2.03,11.108,11.108,77.62,APH,-1.53433,0.0495842,0.00504167,0.953791 beta-lactamase_39_H94I,beta-lactamase_39_94,TEM-1,beta-lactamase_39,P62593,0.953823,NO,94,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-2.5,-2.913,0.413,,0.776,,B,0.17,1.24,11.583,11.583,77.62,HBH,-1.872,0.0495842,0.00389226,0.953823 beta-lactamase_2500_E210L,beta-lactamase_2500_210,TEM-1,beta-lactamase_2500,P62593,0.95383,NO,210,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.319,-2.05,-0.269,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.361275,0.00663582,0.95383 beta-lactamase_2500_L137I,beta-lactamase_2500_137,TEM-1,beta-lactamase_2500,P62593,0.953846,NO,137,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.03,-2.064,1.034,,,H,A,0.55,-0.38,0.769,,42.31,HHP,-1.58933,0.361275,0.00278599,0.953846 kka2_1:8_H135L,kka2_1:8_135,Kka2,kka2_1:8,P00552,0.953859,NO,135,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-1.331,-2.788,1.457,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.100394,0.00532566,0.953859 kka2_1:8_H135L,kka2_1:8_135,Kka2,kka2_1:8,P00552,0.953859,NO,135,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-1.331,-2.788,1.457,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.100394,0.00532566,0.953859 beta-lactamase_39_L74Q,beta-lactamase_39_74,TEM-1,beta-lactamase_39,P62593,0.953874,NO,74,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.296,-4.107,2.811,,,H,A,0.55,-0.91,1.581,,50,HHO,-1.34933,0.0495842,0.00493255,0.953874 beta-lactamase_39_L284Y,beta-lactamase_39_284,TEM-1,beta-lactamase_39,P62593,0.953883,NO,284,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.0495842,0.0686156,0.953883 beta-lactamase_0_G141H,beta-lactamase_0_141,TEM-1,beta-lactamase_0,P62593,0.953885,NO,141,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.828,-4.652,3.824,,0.575,T,l,0.29,-0.28,0.722,,64.69,HOO,-1.08933,0.0500837,0.0012419,0.953885 beta-lactamase_A245S,beta-lactamase_245,TEM-1,beta-lactamase,P62593,0.953885,NO,245,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.068,-2.48,1.412,4.78972,,E,B,0.17,-0.92,0.831,,64.69,HHH,-1.58133,0.221079,0.00391032,0.953885 Pab1_D184K,Pab1_184,Pab1,Pab1,P04147,0.953893,NO,184,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.5,-3.071,1.571,,,,,,,,,,HAH,-1.50133,0.175299,0.0011931,0.953893 kka2_1:8_A65S,kka2_1:8_65,Kka2,kka2_1:8,P00552,0.953901,NO,65,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.744,-2.937,1.193,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.100394,0.00709258,0.953901 kka2_1:8_A65S,kka2_1:8_65,Kka2,kka2_1:8,P00552,0.953901,NO,65,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.744,-2.937,1.193,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.100394,0.00709258,0.953901 beta-lactamase_0_E119L,beta-lactamase_0_119,TEM-1,beta-lactamase_0,P62593,0.953905,NO,119,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.412,-3.669,2.257,,0.358,H,A,1.04,0.51,3.396,,63.99,BAH,-1.623,0.0500837,0.00386966,0.953905 gb1_K239G,gb1_239,gb1,gb1,P06654,0.953923,NO,239,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-3.043,-2.719,-0.324,,,,,,,1.326,,45.54,HBO,-2.31467,0.177985,0.00207004,0.953923 beta-lactamase_156_T263K,beta-lactamase_156_263,TEM-1,beta-lactamase_156,P62593,0.953933,NO,263,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.111618,0.0110582,0.953933 PSD95pdz3_A382P,PSD95pdz3_382,PSD95pdz3,PSD95pdz3,P31016,0.953933,NO,382,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.307,-3.336,2.029,5.30282,,,,,22.472,,,,PHO,-1.24167,0.0758425,0.000249256,0.953933 kka2_1:2_I254V,kka2_1:2_254,Kka2,kka2_1:2,P00552,0.953947,NO,254,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.933,-2.29,0.357,,0.135,H,A,1.52,-0.6,2.562,,71.59,BHH,-1.668,0.295029,0.0132375,0.953947 beta-lactamase_2500_D207V,beta-lactamase_2500_207,TEM-1,beta-lactamase_2500,P62593,0.953953,NO,207,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.064,-3.771,1.707,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.361275,0.00592942,0.953953 beta-lactamase_625_I93F,beta-lactamase_625_93,TEM-1,beta-lactamase_625,P62593,0.95397,NO,93,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.401,-3.88,2.479,,0.128,E,B,0.48,0.44,1.524,,67.83,BHB,-1.873,0.213352,0.00527066,0.95397 beta-lactamase_39_D48H,beta-lactamase_39_48,TEM-1,beta-lactamase_39,P62593,0.953971,NO,48,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.101,-2.659,1.558,,0.189,E,B,0.75,0.21,0.735,,50.35,HAH,-1.62467,0.0495842,0.0027273,0.953971 beta-lactamase_39_D113L,beta-lactamase_39_113,TEM-1,beta-lactamase_39,P62593,0.953985,NO,113,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.829,-3.651,1.822,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.0495842,0.00474112,0.953985 kka2_1:8_G21C,kka2_1:8_21,Kka2,kka2_1:8,P00552,0.954014,NO,21,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.368,-5.139,3.771,,0.586,T,l,0.29,-0.75,4.889,,71.59,HOH,-2.10167,0.100394,0.00709648,0.954014 kka2_1:8_G21C,kka2_1:8_21,Kka2,kka2_1:8,P00552,0.954014,NO,21,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.368,-5.139,3.771,,0.586,T,l,0.29,-0.75,4.889,,71.59,HOH,-2.10167,0.100394,0.00709648,0.954014 beta-lactamase_2500_G90V,beta-lactamase_2500_90,TEM-1,beta-lactamase_2500,P62593,0.954018,NO,90,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-2.091,-3.033,0.942,,0.598,T,A,0.29,0.32,1.2,,77.62,HOB,-1.52633,0.361275,0.00490273,0.954018 beta-lactamase_39_L192K,beta-lactamase_39_192,TEM-1,beta-lactamase_39,P62593,0.954025,NO,192,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.254,-3.803,2.549,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.0495842,0.00558728,0.954025 beta-lactamase_39_A200M,beta-lactamase_39_200,TEM-1,beta-lactamase_39,P62593,0.954045,NO,200,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.878,-4.732,2.854,,0.757,H,A,0.46,-0.19,1.54,,77.62,HHP,-2.001,0.0495842,0.0060056,0.954045 beta-lactamase_0_R242I,beta-lactamase_0_242,TEM-1,beta-lactamase_0,P62593,0.954048,NO,242,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.0500837,0.00452879,0.954048 PSD95pdz3_R368F,PSD95pdz3_368,PSD95pdz3,PSD95pdz3,P31016,0.954081,NO,368,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.582,-3.974,2.392,6.13355,,,,,18.1818,,,,HBP,-1.50033,0.0758425,0.000451517,0.954081 beta-lactamase_2500_R239S,beta-lactamase_2500_239,TEM-1,beta-lactamase_2500,P62593,0.954094,NO,239,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.361275,0.00213852,0.954094 beta-lactamase_39_D113Q,beta-lactamase_39_113,TEM-1,beta-lactamase_39,P62593,0.954094,NO,113,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.829,-2.873,1.044,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.0495842,0.00474112,0.954094 beta-lactamase_2500_H156I,beta-lactamase_2500_156,TEM-1,beta-lactamase_2500,P62593,0.954122,NO,156,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-3.156,-4.08,0.924,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.361275,0.00468596,0.954122 beta-lactamase_F22A,beta-lactamase_22,TEM-1,beta-lactamase,P62593,0.954131,NO,22,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-2.676,-3.278,0.602,,,,,,,1.616,,73.08,HHH,-2.03233,0.221079,0.00262842,0.954131 beta-lactamase_R63K,beta-lactamase_63,TEM-1,beta-lactamase,P62593,0.954131,NO,63,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-0.943,-2.877,1.934,5.49979,0.218,,B,0.45,-0.31,0.677,,44.06,ABH,-0.992333,0.221079,0.00126938,0.954131 gb1_K230H,gb1_230,gb1,gb1,P06654,0.954137,NO,230,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.701,-3.873,2.172,,,,,,,0.166,,11.83,HBH,-1.52867,0.177985,0.00331703,0.954137 beta-lactamase_2500_T269L,beta-lactamase_2500_269,TEM-1,beta-lactamase_2500,P62593,0.954139,NO,269,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.361275,0.00950944,0.954139 beta-lactamase_39_H24P,beta-lactamase_39_24,TEM-1,beta-lactamase_39,P62593,0.954159,NO,24,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-2.481,-3.827,1.346,,,,,,,2.708,,93.01,OBO,-2.0035,0.0495842,0.00238894,0.954159 beta-lactamase_39_I140D,beta-lactamase_39_140,TEM-1,beta-lactamase_39,P62593,0.954204,NO,140,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.733,-4.079,2.346,,0.128,H,A,0.48,0.41,1.16,,73.08,PHO,-1.48733,0.0495842,0.00597777,0.954204 beta-lactamase_39_H287D,beta-lactamase_39_287,TEM-1,beta-lactamase_39,P62593,0.954221,NO,287,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,,,,,,,,,,,,,BBH,-1.111,0.0495842,,0.954221 beta-lactamase_G242A,beta-lactamase_242,TEM-1,beta-lactamase,P62593,0.954234,NO,242,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.319,-2.256,0.937,4.68003,,E,B,0.87,-1.05,1.079,,50,BOH,-1.428,0.221079,0.00452879,0.954234 beta-lactamase_39_P172D,beta-lactamase_39_172,TEM-1,beta-lactamase_39,P62593,0.954253,NO,172,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.998,-3.578,2.58,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.0495842,0.00312594,0.954253 beta-lactamase_F17W,beta-lactamase_17,TEM-1,beta-lactamase,P62593,0.954261,NO,17,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-2.337,-5.109,2.772,,,,,,,2.192,,67.83,HHO,-2.17733,0.221079,0.00216499,0.954261 beta-lactamase_L10S,beta-lactamase_10,TEM-1,beta-lactamase,P62593,0.954261,NO,10,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.623,-2.613,0.99,,,,,,,2.467,,65.38,HHH,-1.83833,0.221079,0.00296968,0.954261 beta-lactamase_S57V,beta-lactamase_57,TEM-1,beta-lactamase,P62593,0.954261,NO,57,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.918,-2.889,0.971,5.64201,0.352,E,B,0.25,-0.18,1.971,,72.73,APH,-2.29167,0.221079,0.00492804,0.954261 Pab1_E176I,Pab1_176,Pab1,Pab1,P04147,0.954289,NO,176,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.003,-3.917,1.914,,,,,,,,,,AAO,-2.09933,0.175299,0.00264426,0.954289 beta-lactamase_39_L111E,beta-lactamase_39_111,TEM-1,beta-lactamase_39,P62593,0.954311,NO,111,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.76,-3.773,2.013,,0.328,T,A,0.55,0.93,4.334,,64.34,BHP,-1.884,0.0495842,0.00480671,0.954311 beta-lactamase_2500_N152C,beta-lactamase_2500_152,TEM-1,beta-lactamase_2500,P62593,0.954314,NO,152,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-2.757,-5.071,2.314,,0.863,H,A,0.61,0.92,2.061,,77.62,BPH,-2.97,0.361275,0.00471429,0.954314 beta-lactamase_2500_A148C,beta-lactamase_2500_148,TEM-1,beta-lactamase_2500,P62593,0.954329,NO,148,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.757,-5.042,3.285,,0.379,H,A,0.46,-0.55,2.117,,72.73,PHH,-1.40167,0.361275,0.00547053,0.954329 beta-lactamase_0_I45N,beta-lactamase_0_45,TEM-1,beta-lactamase_0,P62593,0.954351,NO,45,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-2.421,-3.135,0.714,,,E,B,0.48,-0.3,1.375,,77.62,HHA,-2.30267,0.0500837,0.00452842,0.954351 kka2_1:8_F203W,kka2_1:8_203,Kka2,kka2_1:8,P00552,0.954354,NO,203,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-0.911,-4.558,3.647,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.100394,0.00318738,0.954354 kka2_1:8_F203W,kka2_1:8_203,Kka2,kka2_1:8,P00552,0.954354,NO,203,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-0.911,-4.558,3.647,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.100394,0.00318738,0.954354 beta-lactamase_156_S104H,beta-lactamase_156_104,TEM-1,beta-lactamase_156,P62593,0.95436,NO,104,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.015,-4.582,3.567,,0.04,,b,0.27,0.57,4.02,,63.29,HPO,-1.05267,0.111618,0.00218083,0.95436 beta-lactamase_39_A268L,beta-lactamase_39_268,TEM-1,beta-lactamase_39,P62593,0.954363,NO,268,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.0495842,0.0102525,0.954363 beta-lactamase_T126V,beta-lactamase_126,TEM-1,beta-lactamase,P62593,0.954365,NO,126,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.122,-3.336,2.214,4.82694,0.05,H,A,0.3,-0.05,1.14,,44.41,HPH,-1.60467,0.221079,0.00244552,0.954365 beta-lactamase_0_K286T,beta-lactamase_0_286,TEM-1,beta-lactamase_0,P62593,0.95437,NO,286,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.0500837,,0.95437 beta-lactamase_39_D36P,beta-lactamase_39_36,TEM-1,beta-lactamase_39,P62593,0.954371,NO,36,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.732,-3.967,1.235,,0.555,H,A,0.75,1.17,13.689,13.689,77.62,AAP,-1.91167,0.0495842,0.00476483,0.954371 beta-lactamase_2500_S122I,beta-lactamase_2500_122,TEM-1,beta-lactamase_2500,P62593,0.954372,NO,122,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.406,-3.138,0.732,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.361275,0.00497825,0.954372 beta-lactamase_0_F64Y,beta-lactamase_0_64,TEM-1,beta-lactamase_0,P62593,0.95439,NO,64,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-0.841,-3.037,2.196,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.0500837,0.000947691,0.95439 kka2_1:8_H124T,kka2_1:8_124,Kka2,kka2_1:8,P00552,0.954411,NO,124,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-0.84,-3.675,2.835,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.100394,0.00211296,0.954411 kka2_1:8_H124T,kka2_1:8_124,Kka2,kka2_1:8,P00552,0.954411,NO,124,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-0.84,-3.675,2.835,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.100394,0.00211296,0.954411 PSD95pdz3_R368S,PSD95pdz3_368,PSD95pdz3,PSD95pdz3,P31016,0.954445,NO,368,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.582,-3.067,1.485,6.13355,,,,,18.1818,,,,HBP,-1.50033,0.0758425,0.000451517,0.954445 beta-lactamase_2500_E26I,beta-lactamase_2500_26,TEM-1,beta-lactamase_2500,P62593,0.95445,NO,26,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.454,-3.782,1.328,,0.54,H,A,1.04,0.98,0.49,,93.01,OAP,-1.96167,0.361275,0.00297948,0.95445 beta-lactamase_0_N173K,beta-lactamase_0_173,TEM-1,beta-lactamase_0,P62593,0.954453,NO,173,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-2.663,-2.711,0.048,,1.044,T,l,0.61,1.25,1.133,,77.62,OPA,-1.46633,0.0500837,0.0033769,0.954453 kka2_1:4_T72F,kka2_1:4_72,Kka2,kka2_1:4,P00552,0.954484,NO,72,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.38,-4.46,2.08,,0.784,H,A,0.82,0.29,6.463,,65.53,HPP,-2.238,0.168804,0.00750756,0.954484 PSD95pdz3_N381V,PSD95pdz3_381,PSD95pdz3,PSD95pdz3,P31016,0.954506,NO,381,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-1.41,-3.435,2.025,5.66057,,,,,28.2162,,,,BPH,-1.37767,0.0758425,0.000265374,0.954506 kka2_1:8_T125N,kka2_1:8_125,Kka2,kka2_1:8,P00552,0.954524,NO,125,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.622,-3.781,1.159,,0.791,T,A,0.22,0.33,2.675,,92.05,BPH,-1.56933,0.100394,0.00821755,0.954524 kka2_1:8_T125N,kka2_1:8_125,Kka2,kka2_1:8,P00552,0.954524,NO,125,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.622,-3.781,1.159,,0.791,T,A,0.22,0.33,2.675,,92.05,BPH,-1.56933,0.100394,0.00821755,0.954524 beta-lactamase_625_L136A,beta-lactamase_625_136,TEM-1,beta-lactamase_625,P62593,0.95455,NO,136,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.232,-3.144,1.912,,,H,A,0.55,-0.34,0.336,,48.95,HHH,-1.088,0.213352,0.00442304,0.95455 beta-lactamase_39_K144S,beta-lactamase_39_144,TEM-1,beta-lactamase_39,P62593,0.954551,NO,144,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-2.388,-2.51,0.122,,0.863,H,A,2.34,1.27,14.556,14.556,77.62,OBA,-1.904,0.0495842,0.00481141,0.954551 beta-lactamase_39_Q276F,beta-lactamase_39_276,TEM-1,beta-lactamase_39,P62593,0.954552,NO,276,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.0495842,0.0191712,0.954552 Pab1_S165V,Pab1_165,Pab1,Pab1,P04147,0.954627,NO,165,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.146,-3.346,2.2,,0.12,,a,,0.11,,,,BPB,-1.56867,0.175299,0.000307838,0.954627 beta-lactamase_K53D,beta-lactamase_53,TEM-1,beta-lactamase,P62593,0.954636,NO,53,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-2.313,-3.725,1.412,5.93654,0.589,,B,1.82,1.15,19.72,19.72,77.62,OBH,-2.1,0.221079,0.00383383,0.954636 beta-lactamase_R81Q,beta-lactamase_81,TEM-1,beta-lactamase,P62593,0.954636,NO,81,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.466,-2.446,0.98,5.12166,0.218,H,A,0.68,1.66,1.236,,50,PBH,-1.60667,0.221079,0.00499763,0.954636 beta-lactamase_39_S104D,beta-lactamase_39_104,TEM-1,beta-lactamase_39,P62593,0.954639,NO,104,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.015,-3.41,2.395,,0.04,,b,0.27,0.57,4.02,,63.29,HPO,-1.05267,0.0495842,0.00218083,0.954639 beta-lactamase_0_Q88R,beta-lactamase_0_88,TEM-1,beta-lactamase_0,P62593,0.954661,NO,88,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.086,-2.458,0.372,,0.807,,B,0.64,2.03,0.4,,77.62,APH,-1.53433,0.0500837,0.00504167,0.954661 beta-lactamase_39_Q203S,beta-lactamase_39_203,TEM-1,beta-lactamase_39,P62593,0.954663,NO,203,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.168,-2.824,0.656,,0.47,H,A,0.64,-0.38,1.453,,65.38,BPP,-1.614,0.0495842,0.00631514,0.954663 beta-lactamase_39_L248W,beta-lactamase_39_248,TEM-1,beta-lactamase_39,P62593,0.954671,NO,248,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.0495842,0.00428493,0.954671 beta-lactamase_0_L74G,beta-lactamase_0_74,TEM-1,beta-lactamase_0,P62593,0.95468,NO,74,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.296,-3.477,2.181,,,H,A,0.55,-0.91,1.46,,50,HHO,-1.34933,0.0500837,0.00493255,0.95468 kka2_1:8_R122S,kka2_1:8_122,Kka2,kka2_1:8,P00552,0.954694,NO,122,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.175,-2.833,0.658,,0.487,H,A,1.2,0.26,22.675,22.675,71.59,BBH,-1.53833,0.100394,0.00736512,0.954694 kka2_1:8_R122S,kka2_1:8_122,Kka2,kka2_1:8,P00552,0.954694,NO,122,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.175,-2.833,0.658,,0.487,H,A,1.2,0.26,22.675,22.675,71.59,BBH,-1.53833,0.100394,0.00736512,0.954694 kka2_1:4_Q136E,kka2_1:4_136,Kka2,kka2_1:4,P00552,0.954697,NO,136,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-3.021,-3.472,0.451,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.168804,0.00624149,0.954697 beta-lactamase_39_S256Y,beta-lactamase_39_256,TEM-1,beta-lactamase_39,P62593,0.954699,NO,256,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.0495842,0.00710634,0.954699 beta-lactamase_V42M,beta-lactamase_42,TEM-1,beta-lactamase,P62593,0.954709,NO,42,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.564,-2.813,1.249,5.27904,0.017,E,B,1.64,-0.51,2.024,,63.99,BHO,-1.042,0.221079,0.00404515,0.954709 beta-lactamase_39_K144D,beta-lactamase_39_144,TEM-1,beta-lactamase_39,P62593,0.954712,NO,144,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-2.388,-3.584,1.196,,0.863,H,A,2.34,1.27,14.556,14.556,77.62,OBA,-1.904,0.0495842,0.00481141,0.954712 beta-lactamase_0_V82C,beta-lactamase_0_82,TEM-1,beta-lactamase_0,P62593,0.954728,NO,82,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.325,-4.774,3.449,,0.267,H,A,0.44,0.08,1.893,,93.01,BHA,-1.28567,0.0500837,0.00397046,0.954728 WW_domain_R187Y,WW_domain_187,Yap65,WW_domain,P46937,0.954732,NO,187,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.402,-4.003,2.601,5.05189,,,,,,3.431,,78.57,PBH,-1.362,0.153962,0.00171149,0.954732 kka2_1:8_A150R,kka2_1:8_150,Kka2,kka2_1:8,P00552,0.954734,NO,150,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.949,-3.769,2.82,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.100394,0.0045009,0.954734 kka2_1:8_A150R,kka2_1:8_150,Kka2,kka2_1:8,P00552,0.954734,NO,150,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.949,-3.769,2.82,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.100394,0.0045009,0.954734 beta-lactamase_2500_R273Q,beta-lactamase_2500_273,TEM-1,beta-lactamase_2500,P62593,0.954743,NO,273,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.314,-2.364,0.05,,0.564,H,A,1.2,1.57,19.943,19.943,73.78,ABP,-1.841,0.361275,0.0077952,0.954743 beta-lactamase_0_A278S,beta-lactamase_0_278,TEM-1,beta-lactamase_0,P62593,0.954756,NO,278,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.348,,,,0.015,H,A,0.48,-0.85,4.624,,63.29,HHA,-1.41833,0.0500837,0.0310297,0.954756 beta-lactamase_625_T107M,beta-lactamase_625_107,TEM-1,beta-lactamase_625,P62593,0.954768,NO,107,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.117,-4.531,3.414,,,G,A,0.22,-0.06,3.676,,67.83,HPA,-1.265,0.213352,0.00239347,0.954768 gb1_K276F,gb1_276,gb1,gb1,P06654,0.954778,NO,276,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.456,-4.132,2.676,,,,,,,0.236,,12.72,PBP,-1.65133,0.177985,0.00620493,0.954778 beta-lactamase_625_S241D,beta-lactamase_625_241,TEM-1,beta-lactamase_625,P62593,0.954791,NO,241,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.213352,0.00452736,0.954791 beta-lactamase_2500_M180W,beta-lactamase_2500_180,TEM-1,beta-lactamase_2500,P62593,0.954799,NO,180,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-2.795,-5.124,2.329,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.361275,0.00552048,0.954799 WW_domain_T182Y,WW_domain_182,Yap65,WW_domain,P46937,0.954826,NO,182,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.149,-3.939,2.79,6.20597,,,,,,,,,BPP,-1.483,0.153962,0.00294574,0.954826 beta-lactamase_0_W163V,beta-lactamase_0_163,TEM-1,beta-lactamase_0,P62593,0.954828,NO,163,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-1.843,-3.617,1.774,,0.467,,B,0.47,-0.5,13.843,13.843,63.99,BHA,-1.269,0.0500837,0.00418955,0.954828 beta-lactamase_0_P224G,beta-lactamase_0_224,TEM-1,beta-lactamase_0,P62593,0.954842,NO,224,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.893,-3.351,2.458,,0.383,,B,0.52,-0.3,3.587,,74.48,HOH,-1.26433,0.0500837,0.00189564,0.954842 beta-lactamase_R41Q,beta-lactamase_41,TEM-1,beta-lactamase,P62593,0.954849,NO,41,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-0.942,-3.498,2.556,5.69185,0.321,E,B,0.91,-0.07,4.357,,65.03,HBH,-1.30267,0.221079,0.00123327,0.954849 beta-lactamase_39_M153R,beta-lactamase_39_153,TEM-1,beta-lactamase_39,P62593,0.954857,NO,153,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-3.193,-4.075,0.882,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.0495842,0.00509109,0.954857 beta-lactamase_2500_A170Y,beta-lactamase_2500_170,TEM-1,beta-lactamase_2500,P62593,0.954877,NO,170,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.237,-4.057,2.82,,0.126,,L,0.46,-0.35,2.427,,64.69,AHH,-1.63267,0.361275,0.00431903,0.954877 beta-lactamase_156_G114R,beta-lactamase_156_114,TEM-1,beta-lactamase_156,P62593,0.954888,NO,114,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.094,-2.891,1.797,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.111618,0.00224919,0.954888 beta-lactamase_39_N168K,beta-lactamase_39_168,TEM-1,beta-lactamase_39,P62593,0.954891,NO,168,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-1.029,-3.307,2.278,,0.113,G,A,0.61,-0.4,0.822,,44.41,HPA,-1.13233,0.0495842,0.00288667,0.954891 beta-lactamase_R189T,beta-lactamase_189,TEM-1,beta-lactamase,P62593,0.954894,NO,189,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.844,-3.622,1.778,5.74877,0.278,H,A,0.68,1.01,1.512,,72.73,HBB,-1.668,0.221079,0.0050699,0.954894 beta-lactamase_156_G142C,beta-lactamase_156_142,TEM-1,beta-lactamase_156,P62593,0.954895,NO,142,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.707,-5.05,4.343,,0.034,,p,0.29,-0.64,0.325,,64.69,OOO,-0.834,0.111618,0.00060149,0.954895 beta-lactamase_0_T27P,beta-lactamase_0_27,TEM-1,beta-lactamase_0,P62593,0.954897,NO,27,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.905,-1.921,0.016,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.0500837,0.00306559,0.954897 E1_Ubiquitin_G47F,E1_Ubiquitin_47,Uba1,E1_Ubiquitin,P0CG63,0.954907,NO,47,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.999,-4.162,3.163,,0.057,T,l,,-1.21,,,,HOB,-1.195,0.18783,0.00142261,0.954907 kka2_1:2_R173D,kka2_1:2_173,Kka2,kka2_1:2,P00552,0.954911,NO,173,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.407,-2.431,0.024,,0.308,H,A,0.16,-0.13,15.389,15.389,65.53,HBH,-1.70533,0.295029,0.00784999,0.954911 beta-lactamase_2500_T263S,beta-lactamase_2500_263,TEM-1,beta-lactamase_2500,P62593,0.954913,NO,263,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.361275,0.0110582,0.954913 kka2_1:1_D156Q,kka2_1:1_156,Kka2,kka2_1:1,P00552,0.95492,NO,156,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.696,-3.891,2.195,,0.884,T,A,0.75,1.87,1.044,,65.53,PAA,-1.765,0.520039,0.00926998,0.95492 kka2_1:8_P76Q,kka2_1:8_76,Kka2,kka2_1:8,P00552,0.95492,NO,76,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.449,-3.171,1.722,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.100394,0.00625685,0.95492 kka2_1:8_P76Q,kka2_1:8_76,Kka2,kka2_1:8,P00552,0.95492,NO,76,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.449,-3.171,1.722,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.100394,0.00625685,0.95492 beta-lactamase_L219V,beta-lactamase_219,TEM-1,beta-lactamase,P62593,0.954924,NO,219,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.313,-2.847,1.534,5.74153,,I,A,0.84,-0.51,2.321,,74.48,HHB,-1.21533,0.221079,0.00664345,0.954924 beta-lactamase_R81F,beta-lactamase_81,TEM-1,beta-lactamase,P62593,0.954924,NO,81,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.466,-4.359,2.893,5.12166,0.218,H,A,0.68,1.66,1.236,,50,PBH,-1.60667,0.221079,0.00499763,0.954924 beta-lactamase_V8P,beta-lactamase_8,TEM-1,beta-lactamase,P62593,0.954924,NO,8,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-2.358,-3.968,1.61,,,,,,,0.575,,77.62,BHH,-2.06267,0.221079,0.00226401,0.954924 beta-lactamase_39_L188F,beta-lactamase_39_188,TEM-1,beta-lactamase_39,P62593,0.954947,NO,188,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.166,-3.771,2.605,,,H,A,0.55,-0.3,2.982,,60.14,PHB,-1.47033,0.0495842,0.00295687,0.954947 beta-lactamase_E26V,beta-lactamase_26,TEM-1,beta-lactamase,P62593,0.954994,NO,26,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.454,-2.776,0.322,,0.54,H,A,1.04,0.98,,,93.01,OAP,-1.96167,0.221079,0.00297948,0.954994 beta-lactamase_39_G240N,beta-lactamase_39_240,TEM-1,beta-lactamase_39,P62593,0.955007,NO,240,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.0495842,0.00591201,0.955007 beta-lactamase_0_D36V,beta-lactamase_0_36,TEM-1,beta-lactamase_0,P62593,0.955035,NO,36,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.732,-3.726,0.994,,0.555,H,A,0.75,1.17,13.689,13.689,77.62,AAP,-1.91167,0.0500837,0.00476483,0.955035 beta-lactamase_39_A148Y,beta-lactamase_39_148,TEM-1,beta-lactamase_39,P62593,0.955054,NO,148,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.757,-4.336,2.579,,0.379,H,A,0.46,-0.55,3.551,,72.73,PHH,-1.40167,0.0495842,0.00547053,0.955054 beta-lactamase_0_I261P,beta-lactamase_0_261,TEM-1,beta-lactamase_0,P62593,0.955086,NO,261,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.0500837,0.0123091,0.955086 Pab1_H134A,Pab1_134,Pab1,Pab1,P04147,0.95509,NO,134,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-1.542,-3.234,1.692,,,,,,,,,,HBO,-1.346,0.175299,0.00116356,0.95509 beta-lactamase_0_A211G,beta-lactamase_0_211,TEM-1,beta-lactamase_0,P62593,0.95512,NO,211,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.896,-2.355,0.459,,0.369,T,A,0.46,-0.69,8.527,8.527,77.62,AHA,-1.94633,0.0500837,0.00648183,0.95512 beta-lactamase_2500_R189N,beta-lactamase_2500_189,TEM-1,beta-lactamase_2500,P62593,0.955125,NO,189,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.844,-3.633,1.789,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.361275,0.0050699,0.955125 beta-lactamase_39_K144A,beta-lactamase_39_144,TEM-1,beta-lactamase_39,P62593,0.955134,NO,144,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-2.388,-2.013,-0.375,,0.863,H,A,2.34,1.27,14.556,14.556,77.62,OBA,-1.904,0.0495842,0.00481141,0.955134 beta-lactamase_0_V82R,beta-lactamase_0_82,TEM-1,beta-lactamase_0,P62593,0.955139,NO,82,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.325,-4.101,2.776,,0.267,H,A,0.44,0.08,1.893,,93.01,BHA,-1.28567,0.0500837,0.00397046,0.955139 beta-lactamase_0_N168G,beta-lactamase_0_168,TEM-1,beta-lactamase_0,P62593,0.955163,NO,168,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-1.029,-3.01,1.981,,0.113,G,A,0.61,-0.4,0.881,,44.41,HPA,-1.13233,0.0500837,0.00288667,0.955163 beta-lactamase_0_E62T,beta-lactamase_0_62,TEM-1,beta-lactamase_0,P62593,0.95521,NO,62,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.193,-3.522,2.329,,0.342,S,B,1.04,-0.3,5.784,,73.08,AAB,-1.417,0.0500837,0.00264802,0.95521 beta-lactamase_39_E195N,beta-lactamase_39_195,TEM-1,beta-lactamase_39,P62593,0.955219,NO,195,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.186,-2.977,0.791,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.0495842,0.00496565,0.955219 kka2_1:2_T72H,kka2_1:2_72,Kka2,kka2_1:2,P00552,0.955247,NO,72,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.38,-4.753,2.373,,0.784,H,A,0.82,0.29,6.463,,65.53,HPP,-2.238,0.295029,0.00750756,0.955247 kka2_1:8_G10I,kka2_1:8_10,Kka2,kka2_1:8,P00552,0.955259,NO,10,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.921,-4.096,2.175,,,,,,,1.862,,71.59,HOP,-2.10733,0.100394,0.00289233,0.955259 kka2_1:8_G10I,kka2_1:8_10,Kka2,kka2_1:8,P00552,0.955259,NO,10,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.921,-4.096,2.175,,,,,,,1.862,,71.59,HOP,-2.10733,0.100394,0.00289233,0.955259 beta-lactamase_0_A133S,beta-lactamase_0_133,TEM-1,beta-lactamase_0,P62593,0.955264,NO,133,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.186,-3.092,1.906,,,H,A,0.46,-0.86,2.148,,67.83,HHP,-0.988333,0.0500837,0.00468022,0.955264 kka2_1:1_E3I,kka2_1:1_3,Kka2,kka2_1:1,P00552,0.955268,NO,3,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.199,-3.832,1.633,,,,,,,3.435,,92.05,HAP,-2.11567,0.520039,0.00267607,0.955268 kka2_1:1_V242D,kka2_1:1_242,Kka2,kka2_1:1,P00552,0.955295,NO,242,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-2.687,-2.207,-0.48,,0.75,H,A,0.44,-0.37,4.987,,71.59,HHH,-2.16533,0.520039,0.0102575,0.955295 PSD95pdz3_T385Y,PSD95pdz3_385,PSD95pdz3,PSD95pdz3,P31016,0.955307,NO,385,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.533,-3.939,2.406,5.57157,,,,,23.6871,4.527,,87.71,PPH,-1.56567,0.0758425,0.000545119,0.955307 kka2_1:1_S11S,kka2_1:1_11,Kka2,kka2_1:1,P00552,0.955318,NO,11,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.322,-2.322,,,0.408,,B,0.77,1.64,2.054,,92.05,OPO,-1.69867,0.520039,0.00381691,0.955318 kka2_1:8_F240V,kka2_1:8_240,Kka2,kka2_1:8,P00552,0.955334,NO,240,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-0.911,-3.287,2.376,,,H,A,1.62,-1.21,0.697,,50.38,BHH,-1.67267,0.100394,0.00552543,0.955334 kka2_1:8_F240V,kka2_1:8_240,Kka2,kka2_1:8,P00552,0.955334,NO,240,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-0.911,-3.287,2.376,,,H,A,1.62,-1.21,0.697,,50.38,BHH,-1.67267,0.100394,0.00552543,0.955334 beta-lactamase_A34I,beta-lactamase_34,TEM-1,beta-lactamase,P62593,0.955335,NO,34,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.059,-2.06,0.001,4.9129,,H,A,0.75,-0.54,3.614,,73.78,AHA,-1.74967,0.221079,0.00407913,0.955335 beta-lactamase_E26Q,beta-lactamase_26,TEM-1,beta-lactamase,P62593,0.955335,NO,26,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.454,-2.296,-0.158,,0.54,H,A,1.04,0.98,,,93.01,OAP,-1.96167,0.221079,0.00297948,0.955335 beta-lactamase_F6C,beta-lactamase_6,TEM-1,beta-lactamase,P62593,0.955335,NO,6,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.847,-4.663,2.816,,,,,,,1.276,,67.83,BHB,-2.076,0.221079,0.00261627,0.955335 beta-lactamase_G216T,beta-lactamase_216,TEM-1,beta-lactamase,P62593,0.955335,NO,216,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.477,-3.599,2.122,4.91694,0.437,I,A,0.23,-0.58,1.718,,74.48,HOO,-1.68067,0.221079,0.00639568,0.955335 beta-lactamase_H151F,beta-lactamase_151,TEM-1,beta-lactamase,P62593,0.955335,NO,151,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-2.96,-4.308,1.348,5.47408,0.594,H,A,0.35,0.1,1.843,,77.62,HBP,-2.34767,0.221079,0.00216946,0.955335 beta-lactamase_K190C,beta-lactamase_190,TEM-1,beta-lactamase,P62593,0.955335,NO,190,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.994,-5.082,3.088,5.49163,0.371,H,A,1.82,0.16,29.753,29.753,77.62,BBH,-1.64167,0.221079,0.00574527,0.955335 beta-lactamase_N50W,beta-lactamase_50,TEM-1,beta-lactamase,P62593,0.955335,NO,50,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-2.979,-5.454,2.475,5.51261,0.912,T,A,1.07,1.24,1.581,,77.62,HPP,-2.134,0.221079,0.0047211,0.955335 beta-lactamase_V106A,beta-lactamase_106,TEM-1,beta-lactamase,P62593,0.955335,NO,106,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.218,-3.084,1.866,5.23115,0.258,T,A,0.96,0.24,1.188,,72.73,OHP,-1.04933,0.221079,0.00304168,0.955335 beta-lactamase_0_E56P,beta-lactamase_0_56,TEM-1,beta-lactamase_0,P62593,0.955342,NO,56,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.043,-3.731,1.688,,0.198,E,B,1.04,0.31,1.491,,72.73,HAP,-1.94033,0.0500837,0.00238534,0.955342 beta-lactamase_156_F64W,beta-lactamase_156_64,TEM-1,beta-lactamase_156,P62593,0.955344,NO,64,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-0.841,-4.422,3.581,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.111618,0.000947691,0.955344 Pab1_Y197A,Pab1_197,Pab1,Pab1,P04147,0.955344,NO,197,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-1.345,-3.216,1.871,,,,,,,0.891,,80.42,HHH,-1.41767,0.175299,0.00302474,0.955344 beta-lactamase_39_V42S,beta-lactamase_39_42,TEM-1,beta-lactamase_39,P62593,0.955359,NO,42,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.564,-3.633,2.069,,0.017,E,B,0.44,-0.51,1.86,,63.99,BHO,-1.042,0.0495842,0.00404515,0.955359 Pab1_L142V,Pab1_142,Pab1,Pab1,P04147,0.955374,NO,142,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.039,-2.671,1.632,,0.007,H,A,0.84,-0.65,,,,HHH,-1.487,0.175299,0.000335477,0.955374 beta-lactamase_2500_A40S,beta-lactamase_2500_40,TEM-1,beta-lactamase_2500,P62593,0.955398,NO,40,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.402,-3.164,1.762,,0.155,S,B,0.46,0.21,0.953,,73.78,OHB,-1.40267,0.361275,0.00490026,0.955398 PSD95pdz3_A382R,PSD95pdz3_382,PSD95pdz3,PSD95pdz3,P31016,0.955408,NO,382,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.307,-3.39,2.083,5.30282,,,,,22.472,,,,PHO,-1.24167,0.0758425,0.000249256,0.955408 beta-lactamase_156_W227M,beta-lactamase_156_227,TEM-1,beta-lactamase_156,P62593,0.955414,NO,227,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-0.982,-4.54,3.558,,0.272,,B,0.47,-0.29,2.533,,74.48,OHH,-1.595,0.111618,0.00226019,0.955414 beta-lactamase_0_A170S,beta-lactamase_0_170,TEM-1,beta-lactamase_0,P62593,0.955418,NO,170,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.237,-3.188,1.951,,0.126,,L,0.46,-0.35,2.427,,64.69,AHH,-1.63267,0.0500837,0.00431903,0.955418 beta-lactamase_156_S266P,beta-lactamase_156_266,TEM-1,beta-lactamase_156,P62593,0.955423,NO,266,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.111618,0.0140785,0.955423 beta-lactamase_2500_A84Y,beta-lactamase_2500_84,TEM-1,beta-lactamase_2500,P62593,0.955455,NO,84,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.651,-4.29,2.639,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.361275,0.00503822,0.955455 beta-lactamase_156_I261W,beta-lactamase_156_261,TEM-1,beta-lactamase_156,P62593,0.955456,NO,261,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.111618,0.0123091,0.955456 PSD95pdz3_R368N,PSD95pdz3_368,PSD95pdz3,PSD95pdz3,P31016,0.955485,NO,368,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.582,-3.13,1.548,6.13355,,,,,18.1818,,,,HBP,-1.50033,0.0758425,0.000451517,0.955485 beta-lactamase_R81H,beta-lactamase_81,TEM-1,beta-lactamase,P62593,0.955486,NO,81,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.466,-4.464,2.998,5.12166,0.218,H,A,0.68,1.66,1.236,,50,PBH,-1.60667,0.221079,0.00499763,0.955486 beta-lactamase_0_T198G,beta-lactamase_0_198,TEM-1,beta-lactamase_0,P62593,0.955497,NO,198,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.168,-3.295,1.127,,0.489,,B,0.22,-0.13,9.874,,73.78,HPH,-1.98767,0.0500837,0.004311,0.955497 beta-lactamase_625_D271K,beta-lactamase_625_271,TEM-1,beta-lactamase_625,P62593,0.955498,NO,271,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.213352,0.00752082,0.955498 kka2_1:8_A71S,kka2_1:8_71,Kka2,kka2_1:8,P00552,0.955504,NO,71,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.824,-2.597,0.773,,0.553,H,A,0.46,0.08,18.64,18.64,64.39,HHP,-1.74033,0.100394,0.00727707,0.955504 kka2_1:8_A71S,kka2_1:8_71,Kka2,kka2_1:8,P00552,0.955504,NO,71,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.824,-2.597,0.773,,0.553,H,A,0.46,0.08,18.64,18.64,64.39,HHP,-1.74033,0.100394,0.00727707,0.955504 beta-lactamase_39_D48G,beta-lactamase_39_48,TEM-1,beta-lactamase_39,P62593,0.955505,NO,48,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.101,-3.259,2.158,,0.189,E,B,0.75,0.21,0.735,,50.35,HAH,-1.62467,0.0495842,0.0027273,0.955505 beta-lactamase_0_Q276V,beta-lactamase_0_276,TEM-1,beta-lactamase_0,P62593,0.955511,NO,276,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.0500837,0.0191712,0.955511 beta-lactamase_2500_P172K,beta-lactamase_2500_172,TEM-1,beta-lactamase_2500,P62593,0.95552,NO,172,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.998,-3.522,2.524,,0.639,T,b,0.52,0.24,4.99,,74.48,HOP,-2.03067,0.361275,0.00312594,0.95552 hsp90_A587S,hsp90_587,hsp90,hsp90,P02829,0.955551,NO,587,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.456,-2.764,0,4.91216,0.049,H,A,0.55,-0.02,,,,PHP,-2.757,0.368192,0.000222939,0.955551 beta-lactamase_2500_K213A,beta-lactamase_2500_213,TEM-1,beta-lactamase_2500,P62593,0.955567,NO,213,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.81,-3.194,1.384,,0.67,,A,2.34,0.29,1.668,,67.83,ABH,-1.57767,0.361275,0.00610411,0.955567 beta-lactamase_156_G114E,beta-lactamase_156_114,TEM-1,beta-lactamase_156,P62593,0.95557,NO,114,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.094,-3.605,2.511,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.111618,0.00224919,0.95557 beta-lactamase_625_G114N,beta-lactamase_625_114,TEM-1,beta-lactamase_625,P62593,0.955571,NO,114,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.094,-2.731,1.637,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.213352,0.00224919,0.955571 beta-lactamase_G226R,beta-lactamase_226,TEM-1,beta-lactamase,P62593,0.955592,NO,226,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.461,-3.022,1.561,5.70682,0.701,T,l,0.77,-0.25,3.199,,74.48,HOH,-1.42933,0.221079,0.00665294,0.955592 beta-lactamase_2500_A246G,beta-lactamase_2500_246,TEM-1,beta-lactamase_2500,P62593,0.955594,NO,246,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.121,-3.675,1.554,,0.01,E,B,0.46,-1.01,0.753,,73.78,HHH,-1.55633,0.361275,0.00569458,0.955594 beta-lactamase_39_G52H,beta-lactamase_39_52,TEM-1,beta-lactamase_39,P62593,0.955603,NO,52,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.149,-4.712,3.563,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.0495842,0.00340138,0.955603 beta-lactamase_39_D36H,beta-lactamase_39_36,TEM-1,beta-lactamase_39,P62593,0.955608,NO,36,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.732,-3.09,0.358,,0.555,H,A,0.75,1.17,13.689,13.689,77.62,AAP,-1.91167,0.0495842,0.00476483,0.955608 beta-lactamase_625_V101Q,beta-lactamase_625_101,TEM-1,beta-lactamase_625,P62593,0.955612,NO,101,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.295,-4.106,2.811,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.213352,0.00374492,0.955612 beta-lactamase_625_S51I,beta-lactamase_625_51,TEM-1,beta-lactamase_625,P62593,0.955618,NO,51,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.526,-3.925,2.399,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.213352,0.00504821,0.955618 beta-lactamase_2500_L150F,beta-lactamase_2500_150,TEM-1,beta-lactamase_2500,P62593,0.95562,NO,150,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.326,-3.884,2.558,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.361275,0.00463171,0.95562 gb1_T279I,gb1_279,gb1,gb1,P06654,0.955628,NO,279,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.32,-2.176,0.856,,,,,,,0.529,,35.71,HPH,-1.50067,0.177985,0.00421454,0.955628 beta-lactamase_39_D33E,beta-lactamase_39_33,TEM-1,beta-lactamase_39,P62593,0.955629,NO,33,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.321,-2.159,-0.162,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.0495842,0.00435556,0.955629 beta-lactamase_39_Q203E,beta-lactamase_39_203,TEM-1,beta-lactamase_39,P62593,0.955638,NO,203,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.168,-2.449,0.281,,0.47,H,A,0.64,-0.38,1.453,,65.38,BPP,-1.614,0.0495842,0.00631514,0.955638 beta-lactamase_0_M180S,beta-lactamase_0_180,TEM-1,beta-lactamase_0,P62593,0.955646,NO,180,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-2.795,-2.032,-0.763,,0.242,,B,0.55,-0.94,2.892,,77.62,PHO,-1.56433,0.0500837,0.00552048,0.955646 kka2_1:4_L94I,kka2_1:4_94,Kka2,kka2_1:4,P00552,0.955657,NO,94,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.618,-2.284,0.666,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.168804,0.00520888,0.955657 beta-lactamase_0_L137T,beta-lactamase_0_137,TEM-1,beta-lactamase_0,P62593,0.955702,NO,137,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.03,-3.486,2.456,,,H,A,0.55,-0.38,0.328,,42.31,HHP,-1.58933,0.0500837,0.00278599,0.955702 beta-lactamase_625_F228K,beta-lactamase_625_228,TEM-1,beta-lactamase_625,P62593,0.955751,NO,228,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-2.342,-2.864,0.522,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.213352,0.0046669,0.955751 Pab1_G177L,Pab1_177,Pab1,Pab1,P04147,0.955752,NO,177,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-2.24,-3.436,1.196,,,,,,,,,,AOH,-1.94067,0.175299,0.00170727,0.955752 beta-lactamase_2500_P217D,beta-lactamase_2500_217,TEM-1,beta-lactamase_2500,P62593,0.955799,NO,217,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-2.062,-2.498,0.436,,0.496,I,A,0.52,-0.33,0.431,,74.48,OOH,-1.64333,0.361275,0.00463211,0.955799 kka2_1:1_P45Q,kka2_1:1_45,Kka2,kka2_1:1,P00552,0.955802,NO,45,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.774,-2.806,1.032,,0.669,.,B,0.52,-0.76,4.882,,71.59,BOH,-2.152,0.520039,0.00590481,0.955802 kka2_1:1_T225I,kka2_1:1_225,Kka2,kka2_1:1,P00552,0.955815,NO,225,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.393,-3.64,1.247,,0.036,H,A,0.22,-1.22,4.554,,63.64,HPB,-1.58733,0.520039,0.0113598,0.955815 beta-lactamase_2500_H287F,beta-lactamase_2500_287,TEM-1,beta-lactamase_2500,P62593,0.955821,NO,287,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,,,,,,,,,,,,,BBH,-1.111,0.361275,,0.955821 beta-lactamase_625_T158A,beta-lactamase_625_158,TEM-1,beta-lactamase_625,P62593,0.955838,NO,158,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.116,-2.879,1.763,,0.036,,B,0.22,-0.85,3.771,,69.58,HPB,-1.269,0.213352,0.00341825,0.955838 kka2_1:4_L158A,kka2_1:4_158,Kka2,kka2_1:4,P00552,0.955838,NO,158,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.947,-3.292,1.345,,0.095,,B,1.59,0.77,7.588,,63.64,AHA,-1.25333,0.168804,0.00529068,0.955838 gb1_V255W,gb1_255,gb1,gb1,P06654,0.95584,NO,255,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-3.127,-4.651,1.524,,,,,,,1.323,,45.54,BHH,-2.03867,0.177985,0.00408354,0.95584 PSD95pdz3_F340K,PSD95pdz3_340,PSD95pdz3,PSD95pdz3,P31016,0.955862,NO,340,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.524,-3.589,2.065,5.79283,,,,,11.8045,,,,PHH,-1.55767,0.0758425,0.000836987,0.955862 PSD95pdz3_L342Y,PSD95pdz3_342,PSD95pdz3,PSD95pdz3,P31016,0.95589,NO,342,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.347,-3.619,2.272,5.03015,,,,,12.0762,,,,HHH,-1.428,0.0758425,0.00081112,0.95589 beta-lactamase_39_D36L,beta-lactamase_39_36,TEM-1,beta-lactamase_39,P62593,0.955903,NO,36,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.732,-3.628,0.896,,0.555,H,A,0.75,1.17,13.689,13.689,77.62,AAP,-1.91167,0.0495842,0.00476483,0.955903 beta-lactamase_39_S57M,beta-lactamase_39_57,TEM-1,beta-lactamase_39,P62593,0.955905,NO,57,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.918,-4.684,2.766,,0.352,E,B,0.27,-0.18,2.3,,72.73,APH,-2.29167,0.0495842,0.00492804,0.955905 Pab1_I196A,Pab1_196,Pab1,Pab1,P04147,0.955911,NO,196,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.795,-2.813,1.018,,,,,,,2.013,,80.59,AHH,-1.44667,0.175299,0.0016933,0.955911 kka2_1:8_W69F,kka2_1:8_69,Kka2,kka2_1:8,P00552,0.955936,NO,69,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-0.859,-3.388,2.529,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.100394,0.0012874,0.955936 kka2_1:8_W69F,kka2_1:8_69,Kka2,kka2_1:8,P00552,0.955936,NO,69,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-0.859,-3.388,2.529,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.100394,0.0012874,0.955936 kka2_1:8_E142Y,kka2_1:8_142,Kka2,kka2_1:8,P00552,0.955955,NO,142,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.221,-4.391,2.17,,0.471,H,A,1.04,0.85,2.655,,65.53,HAB,-2.08033,0.100394,0.00748883,0.955955 kka2_1:8_E142Y,kka2_1:8_142,Kka2,kka2_1:8,P00552,0.955955,NO,142,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.221,-4.391,2.17,,0.471,H,A,1.04,0.85,2.655,,65.53,HAB,-2.08033,0.100394,0.00748883,0.955955 PSD95pdz3_G345F,PSD95pdz3_345,PSD95pdz3,PSD95pdz3,P31016,0.955957,NO,345,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.008,-3.974,2.966,4.32868,,,,,13.165,,,,OOO,-1.084,0.0758425,0.000771806,0.955957 beta-lactamase_0_N168Y,beta-lactamase_0_168,TEM-1,beta-lactamase_0,P62593,0.955959,NO,168,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-1.029,-4.205,3.176,,0.113,G,A,0.61,-0.4,0.881,,44.41,HPA,-1.13233,0.0500837,0.00288667,0.955959 PSD95pdz3_Q391K,PSD95pdz3_391,PSD95pdz3,PSD95pdz3,P31016,0.955966,NO,391,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-1.699,-2.689,0.99,5.50275,,,,,12.6589,,,,HPH,-1.481,0.0758425,0.000990786,0.955966 beta-lactamase_A183M,beta-lactamase_183,TEM-1,beta-lactamase,P62593,0.955969,NO,183,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.231,-4.59,3.359,4.84712,0.155,H,A,0.55,-0.91,12.189,,77.62,HHH,-1.53367,0.221079,0.00296631,0.955969 beta-lactamase_R118V,beta-lactamase_118,TEM-1,beta-lactamase,P62593,0.955969,NO,118,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.413,-3.595,1.182,5.8227,0.457,H,A,0.68,1.39,2.144,,77.62,HBA,-1.785,0.221079,0.00538794,0.955969 beta-lactamase_2500_V157N,beta-lactamase_2500_157,TEM-1,beta-lactamase_2500,P62593,0.955974,NO,157,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.751,-3.925,2.174,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.361275,0.00506849,0.955974 gb1_K230C,gb1_230,gb1,gb1,P06654,0.956052,NO,230,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.701,-4.779,3.078,,,,,,,0.166,,11.83,HBH,-1.52867,0.177985,0.00331703,0.956052 beta-lactamase_0_A282H,beta-lactamase_0_282,TEM-1,beta-lactamase_0,P62593,0.956065,NO,282,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.0500837,0.0449821,0.956065 PSD95pdz3_L342T,PSD95pdz3_342,PSD95pdz3,PSD95pdz3,P31016,0.956077,NO,342,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.347,-3.103,1.756,5.03015,,,,,12.0762,,,,HHH,-1.428,0.0758425,0.00081112,0.956077 beta-lactamase_39_D161Y,beta-lactamase_39_161,TEM-1,beta-lactamase_39,P62593,0.95608,NO,161,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.891,-4.387,3.496,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.0495842,0.000897697,0.95608 beta-lactamase_625_G52K,beta-lactamase_625_52,TEM-1,beta-lactamase_625,P62593,0.956084,NO,52,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.149,-3.631,2.482,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.213352,0.00340138,0.956084 beta-lactamase_0_P25F,beta-lactamase_0_25,TEM-1,beta-lactamase_0,P62593,0.956085,NO,25,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.526,-4.406,2.88,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.0500837,0.00347571,0.956085 beta-lactamase_0_L135K,beta-lactamase_0_135,TEM-1,beta-lactamase_0,P62593,0.956109,NO,135,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.002,-3.751,2.749,,0.117,H,A,0.55,-0.58,0.705,,43.71,PHH,-1.03767,0.0500837,0.00244423,0.956109 beta-lactamase_39_I206Q,beta-lactamase_39_206,TEM-1,beta-lactamase_39,P62593,0.956126,NO,206,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-2.429,-2.554,0.125,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.0495842,0.00528934,0.956126 beta-lactamase_2500_E272F,beta-lactamase_2500_272,TEM-1,beta-lactamase_2500,P62593,0.956136,NO,272,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.361275,0.00545371,0.956136 kka2_1:1_Q163F,kka2_1:1_163,Kka2,kka2_1:1,P00552,0.956144,NO,163,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.162,-4.196,2.034,,0.58,T,B,0.64,1.85,2.779,,64.02,BPO,-1.78333,0.520039,0.00719507,0.956144 Pab1_G167T,Pab1_167,Pab1,Pab1,P04147,0.956153,NO,167,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.223,-3.471,2.248,,0.195,S,g,,0.03,,,,BOH,-1.25133,0.175299,0.00146449,0.956153 kka2_1:8_P109N,kka2_1:8_109,Kka2,kka2_1:8,P00552,0.956155,NO,109,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.412,-3.924,2.512,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.100394,0.0070929,0.956155 kka2_1:8_P109N,kka2_1:8_109,Kka2,kka2_1:8,P00552,0.956155,NO,109,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.412,-3.924,2.512,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.100394,0.0070929,0.956155 kka2_1:8_A25G,kka2_1:8_25,Kka2,kka2_1:8,P00552,0.956161,NO,25,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.496,-3.533,1.037,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.100394,0.00595636,0.956161 kka2_1:8_A25G,kka2_1:8_25,Kka2,kka2_1:8,P00552,0.956161,NO,25,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.496,-3.533,1.037,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.100394,0.00595636,0.956161 kka2_1:2_P249M,kka2_1:2_249,Kka2,kka2_1:2,P00552,0.956167,NO,249,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.867,-3.186,1.319,,0.406,.,B,0.52,-0.01,0.76,,92.05,HOA,-1.66867,0.295029,0.011045,0.956167 beta-lactamase_39_G114E,beta-lactamase_39_114,TEM-1,beta-lactamase_39,P62593,0.95618,NO,114,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.094,-3.605,2.511,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.0495842,0.00224919,0.95618 beta-lactamase_625_L205F,beta-lactamase_625_205,TEM-1,beta-lactamase_625,P62593,0.956196,NO,205,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.922,-2.306,1.384,,,H,A,0.55,-0.46,3.782,,42.31,PHH,-1.57767,0.213352,0.00255802,0.956196 kka2_1:8_A64L,kka2_1:8_64,Kka2,kka2_1:8,P00552,0.956199,NO,64,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.496,-2.596,1.1,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.100394,0.00705578,0.956199 kka2_1:8_A64L,kka2_1:8_64,Kka2,kka2_1:8,P00552,0.956199,NO,64,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.496,-2.596,1.1,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.100394,0.00705578,0.956199 beta-lactamase_39_T178D,beta-lactamase_39_178,TEM-1,beta-lactamase_39,P62593,0.956222,NO,178,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-0.791,-3.469,2.678,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.0495842,0.000684366,0.956222 kka2_1:8_A248S,kka2_1:8_248,Kka2,kka2_1:8,P00552,0.956236,NO,248,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.124,-2.844,0.72,,0.825,S,b,1.04,0.46,11.329,11.329,92.05,HHO,-2.15,0.100394,0.0125484,0.956236 kka2_1:8_A248S,kka2_1:8_248,Kka2,kka2_1:8,P00552,0.956236,NO,248,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.124,-2.844,0.72,,0.825,S,b,1.04,0.46,11.329,11.329,92.05,HHO,-2.15,0.100394,0.0125484,0.956236 beta-lactamase_156_A215L,beta-lactamase_156_215,TEM-1,beta-lactamase_156,P62593,0.956238,NO,215,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.503,-3.475,1.972,,,,a,0.46,-0.93,3.583,,74.48,HHO,-1.42633,0.111618,0.00544007,0.956238 beta-lactamase_E237V,beta-lactamase_237,TEM-1,beta-lactamase,P62593,0.956244,NO,237,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.058,-3.725,1.667,5.42877,0.583,S,B,1.62,1.2,2.144,,77.62,OAB,-1.61467,0.221079,0.0048626,0.956244 beta-lactamase_0_G52L,beta-lactamase_0_52,TEM-1,beta-lactamase_0,P62593,0.956252,NO,52,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.149,-3.755,2.606,,0.299,,l,0.29,-0.04,1.164,,64.69,POB,-1.66267,0.0500837,0.00340138,0.956252 PSD95pdz3_K380Q,PSD95pdz3_380,PSD95pdz3,PSD95pdz3,P31016,0.956259,NO,380,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.416,-3.131,1.715,5.87979,,,,,19.6722,,,,HBP,-1.391,0.0758425,0.000281399,0.956259 gb1_K230F,gb1_230,gb1,gb1,P06654,0.956263,NO,230,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.701,-3.216,1.515,,,,,,,0.166,,11.83,HBH,-1.52867,0.177985,0.00331703,0.956263 gb1_T242L,gb1_242,gb1,gb1,P06654,0.956263,NO,242,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.245,-2.869,1.624,,,,,,,,,,APP,-1.444,0.177985,0.00243886,0.956263 beta-lactamase_D207F,beta-lactamase_207,TEM-1,beta-lactamase,P62593,0.956265,NO,207,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.064,-4.437,2.373,5.40404,0.409,H,A,0.23,0.12,1.975,,77.62,HAH,-1.77033,0.221079,0.00592942,0.956265 beta-lactamase_0_N274H,beta-lactamase_0_274,TEM-1,beta-lactamase_0,P62593,0.956284,NO,274,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.0500837,0.0110418,0.956284 beta-lactamase_D83E,beta-lactamase_83,TEM-1,beta-lactamase,P62593,0.956288,NO,83,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.066,-2.025,0.959,5.40616,0.354,H,A,1.33,0.22,0.861,,48.95,HAH,-1.34733,0.221079,0.00205968,0.956288 PSD95pdz3_N369D,PSD95pdz3_369,PSD95pdz3,PSD95pdz3,P31016,0.956293,NO,369,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-1.572,-2.88,1.308,5.91569,,,,,24.1262,0.44,,87.71,BPH,-1.487,0.0758425,0.000608412,0.956293 beta-lactamase_39_H287C,beta-lactamase_39_287,TEM-1,beta-lactamase_39,P62593,0.9563,NO,287,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,,,,,,,,,,,,,BBH,-1.111,0.0495842,,0.9563 beta-lactamase_625_G234M,beta-lactamase_625_234,TEM-1,beta-lactamase_625,P62593,0.95634,NO,234,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.62,-4.93,4.31,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.213352,0.000889577,0.95634 beta-lactamase_625_T187Q,beta-lactamase_625_187,TEM-1,beta-lactamase_625,P62593,0.956359,NO,187,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.401,-4.004,2.603,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.213352,0.00491782,0.956359 beta-lactamase_D99A,beta-lactamase_99,TEM-1,beta-lactamase,P62593,0.956361,NO,99,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.191,-2.613,1.422,5.66081,0.402,G,A,0.23,0.36,1.318,,64.69,PAH,-1.794,0.221079,0.00305446,0.956361 beta-lactamase_0_L219T,beta-lactamase_0_219,TEM-1,beta-lactamase_0,P62593,0.956374,NO,219,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.313,-3.55,2.237,,,I,A,0.55,-0.51,6.513,6.513,74.48,HHB,-1.21533,0.0500837,0.00664345,0.956374 beta-lactamase_39_A225M,beta-lactamase_39_225,TEM-1,beta-lactamase_39,P62593,0.956374,NO,225,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.845,-4.778,2.933,,1,T,B,0.46,-0.38,9.874,9.874,74.48,OHO,-1.39967,0.0495842,0.00465057,0.956374 beta-lactamase_S201A,beta-lactamase_201,TEM-1,beta-lactamase,P62593,0.956388,NO,201,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.183,-2.127,0.944,4.85496,0.064,H,A,0.77,-0.07,4.045,,64.69,HPB,-1.451,0.221079,0.00198815,0.956388 kka2_1:8_L103D,kka2_1:8_103,Kka2,kka2_1:8,P00552,0.956405,NO,103,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-2.362,-3.76,1.398,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.100394,0.00574792,0.956405 kka2_1:8_L103D,kka2_1:8_103,Kka2,kka2_1:8,P00552,0.956405,NO,103,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-2.362,-3.76,1.398,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.100394,0.00574792,0.956405 beta-lactamase_0_R189I,beta-lactamase_0_189,TEM-1,beta-lactamase_0,P62593,0.956406,NO,189,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.844,-4.147,2.303,,0.278,H,A,1.2,1.01,12.11,12.11,72.73,HBB,-1.668,0.0500837,0.0050699,0.956406 beta-lactamase_2500_L137M,beta-lactamase_2500_137,TEM-1,beta-lactamase_2500,P62593,0.956418,NO,137,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.03,-2.58,1.55,,,H,A,0.55,-0.38,0.769,,42.31,HHP,-1.58933,0.361275,0.00278599,0.956418 beta-lactamase_39_R273I,beta-lactamase_39_273,TEM-1,beta-lactamase_39,P62593,0.956419,NO,273,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.314,-4.08,1.766,,0.564,H,A,1.2,1.57,2.163,,73.78,ABP,-1.841,0.0495842,0.0077952,0.956419 beta-lactamase_39_K144T,beta-lactamase_39_144,TEM-1,beta-lactamase_39,P62593,0.956435,NO,144,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-2.388,-2.935,0.547,,0.863,H,A,2.34,1.27,14.556,14.556,77.62,OBA,-1.904,0.0495842,0.00481141,0.956435 beta-lactamase_C18G,beta-lactamase_18,TEM-1,beta-lactamase,P62593,0.956437,NO,18,C,G,CG,Special,Special,5.07,3.29388,-1.77612,159,121,75,-46,108.5,60.1,-48.4,-2.26,-2.51,0.25,,,,,,,3.995,,93.01,HOH,-2.093,0.221079,0.002536,0.956437 beta-lactamase_L38I,beta-lactamase_38,TEM-1,beta-lactamase,P62593,0.956437,NO,38,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.343,-2.44,1.097,5.23728,0.088,H,A,1.75,0.2,1.986,,64.34,PHO,-1.78033,0.221079,0.00373244,0.956437 kka2_1:4_L57I,kka2_1:4_57,Kka2,kka2_1:4,P00552,0.956437,NO,57,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.898,-2.89,0.992,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.168804,0.00723769,0.956437 beta-lactamase_0_M67W,beta-lactamase_0_67,TEM-1,beta-lactamase_0,P62593,0.956466,NO,67,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-2.231,-5.379,3.148,,0.006,G,P,0.55,-0.81,24.165,24.165,65.03,HHP,-1.502,0.0500837,0.00409753,0.956466 beta-lactamase_2500_S201M,beta-lactamase_2500_201,TEM-1,beta-lactamase_2500,P62593,0.956483,NO,201,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.183,-4.493,3.31,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.361275,0.00198815,0.956483 PSD95pdz3_K380G,PSD95pdz3_380,PSD95pdz3,PSD95pdz3,P31016,0.956493,NO,380,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.416,-3.04,1.624,5.87979,,,,,19.6722,,,,HBP,-1.391,0.0758425,0.000281399,0.956493 kka2_1:4_A34Q,kka2_1:4_34,Kka2,kka2_1:4,P00552,0.956524,NO,34,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.928,-3.9,2.972,,0.417,.,B,0.46,2.29,0.262,,52.27,AHH,-1.747,0.168804,0.00343484,0.956524 beta-lactamase_0_G52R,beta-lactamase_0_52,TEM-1,beta-lactamase_0,P62593,0.956525,NO,52,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.149,-3.956,2.807,,0.299,,l,0.29,-0.04,1.164,,64.69,POB,-1.66267,0.0500837,0.00340138,0.956525 beta-lactamase_2500_A200M,beta-lactamase_2500_200,TEM-1,beta-lactamase_2500,P62593,0.956534,NO,200,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.878,-4.732,2.854,,0.757,H,A,0.46,-0.19,0.436,,77.62,HHP,-2.001,0.361275,0.0060056,0.956534 beta-lactamase_156_L205T,beta-lactamase_156_205,TEM-1,beta-lactamase_156,P62593,0.956549,NO,205,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.922,-3.476,2.554,,,H,A,0.55,-0.46,0.678,,42.31,PHH,-1.57767,0.111618,0.00255802,0.956549 PSD95pdz3_K393V,PSD95pdz3_393,PSD95pdz3,PSD95pdz3,P31016,0.956555,NO,393,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.416,-3.21,1.794,5.42682,,,,,22.0122,,,,HBO,-1.4265,0.0758425,0.000879298,0.956555 beta-lactamase_39_I206D,beta-lactamase_39_206,TEM-1,beta-lactamase_39,P62593,0.956585,NO,206,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-2.429,-3.794,1.365,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.0495842,0.00528934,0.956585 kka2_1:2_M1R,kka2_1:2_1,Kka2,kka2_1:2,P00552,0.95659,NO,1,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.787,-3.648,1.861,,,,,,,1.347,,62.12,NAHH,-1.787,0.295029,0.00251939,0.95659 hsp90_E590H,hsp90_590,hsp90,hsp90,P02829,0.956608,NO,590,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.818,-3.833,0,4.65049,0.021,H,A,,0.03,,,,HAO,-3.338,0.368192,0.000222939,0.956608 kka2_1:8_Q27F,kka2_1:8_27,Kka2,kka2_1:8,P00552,0.956612,NO,27,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-1.659,-4.291,2.632,,0.608,.,A,0.64,0.71,3.919,,65.53,PPP,-1.90733,0.100394,0.00595365,0.956612 kka2_1:8_Q27F,kka2_1:8_27,Kka2,kka2_1:8,P00552,0.956612,NO,27,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-1.659,-4.291,2.632,,0.608,.,A,0.64,0.71,3.919,,65.53,PPP,-1.90733,0.100394,0.00595365,0.956612 beta-lactamase_156_D48Y,beta-lactamase_156_48,TEM-1,beta-lactamase_156,P62593,0.956618,NO,48,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.101,-4.182,3.081,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.111618,0.0027273,0.956618 beta-lactamase_39_D113Y,beta-lactamase_39_113,TEM-1,beta-lactamase_39,P62593,0.956621,NO,113,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.829,-4.441,2.612,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.0495842,0.00474112,0.956621 beta-lactamase_39_V42H,beta-lactamase_39_42,TEM-1,beta-lactamase_39,P62593,0.95663,NO,42,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.564,-4.991,3.427,,0.017,E,B,0.44,-0.51,1.86,,63.99,BHO,-1.042,0.0495842,0.00404515,0.95663 PSD95pdz3_A370P,PSD95pdz3_370,PSD95pdz3,PSD95pdz3,P31016,0.956645,NO,370,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.307,-3.336,2.029,5.22304,,,,,17.284,,,,PHP,-1.57967,0.0758425,0.000429106,0.956645 beta-lactamase_2500_A225Q,beta-lactamase_2500_225,TEM-1,beta-lactamase_2500,P62593,0.956648,NO,225,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.845,-2.909,1.064,,1,T,B,0.46,-0.38,0.551,,74.48,OHO,-1.39967,0.361275,0.00465057,0.956648 Pab1_E175P,Pab1_175,Pab1,Pab1,P04147,0.956653,NO,175,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.055,-3.76,1.705,,,,,,,,,,AAA,-1.82667,0.175299,0.00203137,0.956653 E1_Ubiquitin_I44I,E1_Ubiquitin_44,Uba1,E1_Ubiquitin,P0CG63,0.956676,NO,44,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.432,-1.432,,,,E,B,0.27,-1.17,4.57,,78.74,HHH,-1.25633,0.18783,0.00209731,0.956676 beta-lactamase_2500_E279G,beta-lactamase_2500_279,TEM-1,beta-lactamase_2500,P62593,0.956679,NO,279,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.038,-3.588,2.55,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.361275,0.0192826,0.956679 beta-lactamase_625_Y103T,beta-lactamase_625_103,TEM-1,beta-lactamase_625,P62593,0.95668,NO,103,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-1.33,-3.696,2.366,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.213352,0.00443048,0.95668 beta-lactamase_39_L197Q,beta-lactamase_39_197,TEM-1,beta-lactamase_39,P62593,0.956683,NO,197,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.853,-4.122,3.269,,0.007,S,B,0.55,0.33,1.559,,60.14,HHP,-1.833,0.0495842,0.00144602,0.956683 gb1_T279N,gb1_279,gb1,gb1,P06654,0.956685,NO,279,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.32,-3.439,2.119,,,,,,,0.529,,35.71,HPH,-1.50067,0.177985,0.00421454,0.956685 gb1_V247M,gb1_247,gb1,gb1,P06654,0.956685,NO,247,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.711,-4.041,2.33,,,,,,,0.805,,44.87,HHA,-1.485,0.177985,0.00435373,0.956685 beta-lactamase_F13C,beta-lactamase_13,TEM-1,beta-lactamase,P62593,0.956686,NO,13,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-2.394,-4.749,2.355,,,,,,,4.079,,77.62,OHH,-2.382,0.221079,0.0029078,0.956686 kka2_1:8_L70V,kka2_1:8_70,Kka2,kka2_1:8,P00552,0.956687,NO,70,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.017,-2.461,1.444,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.100394,0.00411884,0.956687 kka2_1:8_L70V,kka2_1:8_70,Kka2,kka2_1:8,P00552,0.956687,NO,70,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.017,-2.461,1.444,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.100394,0.00411884,0.956687 kka2_1:8_R121H,kka2_1:8_121,Kka2,kka2_1:8,P00552,0.956687,NO,121,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.552,-2.742,1.19,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.100394,0.00523326,0.956687 kka2_1:8_R121H,kka2_1:8_121,Kka2,kka2_1:8,P00552,0.956687,NO,121,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.552,-2.742,1.19,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.100394,0.00523326,0.956687 beta-lactamase_0_E195G,beta-lactamase_0_195,TEM-1,beta-lactamase_0,P62593,0.956696,NO,195,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.186,-2.611,0.425,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.0500837,0.00496565,0.956696 beta-lactamase_E119A,beta-lactamase_119,TEM-1,beta-lactamase,P62593,0.956731,NO,119,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.412,-2.242,0.83,5.33349,0.358,H,A,1.52,0.51,1.983,,63.99,BAH,-1.623,0.221079,0.00386966,0.956731 beta-lactamase_S221Y,beta-lactamase_221,TEM-1,beta-lactamase,P62593,0.95675,NO,221,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.754,-4.278,2.524,5.77407,0.624,H,A,0.74,-0.2,0.383,,74.48,BPH,-1.59967,0.221079,0.0046094,0.95675 beta-lactamase_2500_K32T,beta-lactamase_2500_32,TEM-1,beta-lactamase_2500,P62593,0.956753,NO,32,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.984,-2.479,0.495,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.361275,0.00401283,0.956753 Pab1_S147F,Pab1_147,Pab1,Pab1,P04147,0.956756,NO,147,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.267,-3.937,2.67,,0.336,H,A,,0.56,,,,HPH,-1.43033,0.175299,0.000610856,0.956756 beta-lactamase_0_P217T,beta-lactamase_0_217,TEM-1,beta-lactamase_0,P62593,0.956757,NO,217,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-2.062,-2.679,0.617,,0.496,I,A,0.52,-0.33,1.087,,74.48,OOH,-1.64333,0.0500837,0.00463211,0.956757 beta-lactamase_625_L89E,beta-lactamase_625_89,TEM-1,beta-lactamase_625,P62593,0.956784,NO,89,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.096,-3.801,2.705,,0.168,T,A,0.55,0.63,1.599,,64.34,PHO,-1.75767,0.213352,0.00207068,0.956784 beta-lactamase_0_E145W,beta-lactamase_0_145,TEM-1,beta-lactamase_0,P62593,0.956815,NO,145,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.357,-5.352,2.995,,0.545,H,A,1.04,0.79,1.199,,77.62,BAH,-2.069,0.0500837,0.00553285,0.956815 beta-lactamase_39_D83A,beta-lactamase_39_83,TEM-1,beta-lactamase_39,P62593,0.956817,NO,83,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.066,-3.208,2.142,,0.354,H,A,0.75,0.22,0.752,,48.95,HAH,-1.34733,0.0495842,0.00205968,0.956817 beta-lactamase_F58S,beta-lactamase_58,TEM-1,beta-lactamase,P62593,0.95682,NO,58,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-2.914,-2.895,-0.019,5.55634,0.266,E,B,1.33,-0.07,2.467,,77.62,PHB,-2.059,0.221079,0.00523369,0.95682 beta-lactamase_I140L,beta-lactamase_140,TEM-1,beta-lactamase,P62593,0.95682,NO,140,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.733,-1.622,-0.111,5.29918,0.128,H,A,1,0.41,1.16,,73.08,PHO,-1.48733,0.221079,0.00597777,0.95682 beta-lactamase_I3C,beta-lactamase_3,TEM-1,beta-lactamase,P62593,0.95682,NO,3,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-2.143,-4.63,2.487,,,,,,,3.946,,93.01,PHP,-2.21633,0.221079,0.00349304,0.95682 beta-lactamase_2500_R189T,beta-lactamase_2500_189,TEM-1,beta-lactamase_2500,P62593,0.956832,NO,189,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.844,-3.622,1.778,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.361275,0.0050699,0.956832 Pab1_S147I,Pab1_147,Pab1,Pab1,P04147,0.956832,NO,147,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.267,-3.596,2.329,,0.336,H,A,,0.56,,,,HPH,-1.43033,0.175299,0.000610856,0.956832 beta-lactamase_2500_G90R,beta-lactamase_2500_90,TEM-1,beta-lactamase_2500,P62593,0.956837,NO,90,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-2.091,-3.098,1.007,,0.598,T,A,0.29,0.32,1.2,,77.62,HOB,-1.52633,0.361275,0.00490273,0.956837 beta-lactamase_156_T69V,beta-lactamase_156_69,TEM-1,beta-lactamase_156,P62593,0.956839,NO,69,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-0.973,-3.175,2.202,,,G,A,0.22,-1.24,4.194,,93.01,PPH,-1.01833,0.111618,0.00127498,0.956839 kka2_1:8_V214C,kka2_1:8_214,Kka2,kka2_1:8,P00552,0.956855,NO,214,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.261,-3.243,1.982,,0.117,E,B,1.48,-0.31,1.859,,64.39,OHH,-0.941667,0.100394,0.00692782,0.956855 kka2_1:8_V214C,kka2_1:8_214,Kka2,kka2_1:8,P00552,0.956855,NO,214,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.261,-3.243,1.982,,0.117,E,B,1.48,-0.31,1.859,,64.39,OHH,-0.941667,0.100394,0.00692782,0.956855 beta-lactamase_39_H287E,beta-lactamase_39_287,TEM-1,beta-lactamase_39,P62593,0.956862,NO,287,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,,,,,,,,,,,,,BBH,-1.111,0.0495842,,0.956862 beta-lactamase_2500_M180R,beta-lactamase_2500_180,TEM-1,beta-lactamase_2500,P62593,0.956878,NO,180,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-2.795,-3.843,1.048,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.361275,0.00552048,0.956878 beta-lactamase_0_T27K,beta-lactamase_0_27,TEM-1,beta-lactamase_0,P62593,0.956891,NO,27,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.905,-3.516,1.611,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.0500837,0.00306559,0.956891 beta-lactamase_625_L111M,beta-lactamase_625_111,TEM-1,beta-lactamase_625,P62593,0.956902,NO,111,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.76,-4.22,2.46,,0.328,T,A,0.55,0.93,2.26,,64.34,BHP,-1.884,0.213352,0.00480671,0.956902 kka2_1:1_A14S,kka2_1:1_14,Kka2,kka2_1:1,P00552,0.956909,NO,14,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.837,-2.532,0.695,,0.728,G,A,0.46,0.7,1.17,,71.59,HHH,-1.82567,0.520039,0.00706614,0.956909 beta-lactamase_0_G249L,beta-lactamase_0_249,TEM-1,beta-lactamase_0,P62593,0.956919,NO,249,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.0500837,0.00220169,0.956919 kka2_1:2_I254N,kka2_1:2_254,Kka2,kka2_1:2,P00552,0.956928,NO,254,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.933,-4.208,2.275,,0.135,H,A,1.52,-0.6,2.562,,71.59,BHH,-1.668,0.295029,0.0132375,0.956928 beta-lactamase_156_N134Y,beta-lactamase_156_134,TEM-1,beta-lactamase_156,P62593,0.956931,NO,134,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-0.879,-4.188,3.309,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.111618,0.000644786,0.956931 hsp90_M589W,hsp90_589,hsp90,hsp90,P02829,0.956937,NO,589,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-3.858,-4.251,0,4.72723,0.032,H,A,0.84,0.31,,,,PHA,-3.24233,0.368192,0.000222939,0.956937 beta-lactamase_156_G154V,beta-lactamase_156_154,TEM-1,beta-lactamase_156,P62593,0.956963,NO,154,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.823,-3.725,2.902,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.111618,0.00180205,0.956963 kka2_1:8_A35P,kka2_1:8_35,Kka2,kka2_1:8,P00552,0.956986,NO,35,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.127,-4.029,1.902,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.100394,0.00630016,0.956986 kka2_1:8_A35P,kka2_1:8_35,Kka2,kka2_1:8,P00552,0.956986,NO,35,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.127,-4.029,1.902,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.100394,0.00630016,0.956986 PSD95pdz3_Q384E,PSD95pdz3_384,PSD95pdz3,PSD95pdz3,P31016,0.956998,NO,384,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-1.699,-2.447,0.748,5.49339,,,,,23.54,,,,OPP,-1.41333,0.0758425,0.000216736,0.956998 beta-lactamase_625_L223R,beta-lactamase_625_223,TEM-1,beta-lactamase_625,P62593,0.957015,NO,223,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.055,-4.022,2.967,,0.27,,B,0.55,0.09,1.633,,74.48,HHO,-1.35033,0.213352,0.00372793,0.957015 PSD95pdz3_I338N,PSD95pdz3_338,PSD95pdz3,PSD95pdz3,P31016,0.957033,NO,338,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.63,-3.805,2.175,5.45113,,,,,13.0087,,,,HHP,-1.55767,0.0758425,0.000862587,0.957033 beta-lactamase_P60F,beta-lactamase_60,TEM-1,beta-lactamase,P62593,0.95708,NO,60,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-2.469,-4.292,1.823,5.51353,0.256,T,A,0.73,-0.56,3.653,,77.62,BOA,-1.97633,0.221079,0.00521318,0.95708 PSD95pdz3_G356T,PSD95pdz3_356,PSD95pdz3,PSD95pdz3,P31016,0.95711,NO,356,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.008,-3.328,2.32,4.8656,,,,,11.9575,,,,BOA,-1.22933,0.0758425,0.000623061,0.95711 beta-lactamase_2500_A225T,beta-lactamase_2500_225,TEM-1,beta-lactamase_2500,P62593,0.957123,NO,225,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.845,-2.966,1.121,,1,T,B,0.46,-0.38,0.551,,74.48,OHO,-1.39967,0.361275,0.00465057,0.957123 beta-lactamase_2500_D99M,beta-lactamase_2500_99,TEM-1,beta-lactamase_2500,P62593,0.957134,NO,99,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.191,-3.198,2.007,,0.402,G,A,0.75,0.36,1.318,,64.69,PAH,-1.794,0.361275,0.00305446,0.957134 kka2_1:8_G210S,kka2_1:8_210,Kka2,kka2_1:8,P00552,0.957136,NO,210,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.095,-1.997,0.902,,0.103,T,A,0.75,-0.62,2.687,,50,OOB,-0.966667,0.100394,0.00598378,0.957136 kka2_1:8_G210S,kka2_1:8_210,Kka2,kka2_1:8,P00552,0.957136,NO,210,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.095,-1.997,0.902,,0.103,T,A,0.75,-0.62,2.687,,50,OOB,-0.966667,0.100394,0.00598378,0.957136 beta-lactamase_2500_G281A,beta-lactamase_2500_281,TEM-1,beta-lactamase_2500,P62593,0.957182,NO,281,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.361275,0.0406482,0.957182 hsp90_M589L,hsp90_589,hsp90,hsp90,P02829,0.957187,NO,589,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-3.858,-2.511,0,4.72723,0.032,H,A,0.84,0.31,,,,PHA,-3.24233,0.368192,0.000222939,0.957187 kka2_1:4_R147H,kka2_1:4_147,Kka2,kka2_1:4,P00552,0.957196,NO,147,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.123,-2.32,1.197,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.168804,0.00549168,0.957196 kka2_1:2_L158V,kka2_1:2_158,Kka2,kka2_1:2,P00552,0.95722,NO,158,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.947,-2.604,0.657,,0.095,,B,1.59,0.77,7.588,,63.64,AHA,-1.25333,0.295029,0.00529068,0.95722 beta-lactamase_2500_K32E,beta-lactamase_2500_32,TEM-1,beta-lactamase_2500,P62593,0.957227,NO,32,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.984,-2.418,0.434,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.361275,0.00401283,0.957227 beta-lactamase_E87D,beta-lactamase_87,TEM-1,beta-lactamase,P62593,0.957231,NO,87,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.421,-2.265,0.844,5.41929,0.048,,B,0.52,0.92,1.754,,64.69,PAP,-1.969,0.221079,0.00337888,0.957231 Pab1_S147C,Pab1_147,Pab1,Pab1,P04147,0.957232,NO,147,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.267,-4.508,3.241,,0.336,H,A,,0.56,,,,HPH,-1.43033,0.175299,0.000610856,0.957232 Pab1_F146A,Pab1_146,Pab1,Pab1,P04147,0.957248,NO,146,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.149,-3.12,1.971,,0.006,H,A,,0.75,,,,PHP,-1.161,0.175299,0.000329265,0.957248 beta-lactamase_2500_E279K,beta-lactamase_2500_279,TEM-1,beta-lactamase_2500,P62593,0.957254,NO,279,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.361275,0.0192826,0.957254 beta-lactamase_39_E272R,beta-lactamase_39_272,TEM-1,beta-lactamase_39,P62593,0.957254,NO,272,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.127,,,,0.081,H,A,0.43,-0.97,12.983,12.983,63.64,AAB,-1.56333,0.0495842,0.00545371,0.957254 beta-lactamase_39_T139K,beta-lactamase_39_139,TEM-1,beta-lactamase_39,P62593,0.957257,NO,139,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.901,-3.403,1.502,,0.216,H,A,0.22,0.39,0.421,,77.62,PPH,-2.04667,0.0495842,0.00441837,0.957257 beta-lactamase_156_L188F,beta-lactamase_156_188,TEM-1,beta-lactamase_156,P62593,0.957274,NO,188,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.166,-3.771,2.605,,,H,A,0.55,-0.3,1.574,,60.14,PHB,-1.47033,0.111618,0.00295687,0.957274 beta-lactamase_0_L73N,beta-lactamase_0_73,TEM-1,beta-lactamase_0,P62593,0.957285,NO,73,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.507,-4.234,2.727,,,H,A,0.55,-0.64,0.877,,67.83,HHH,-1.487,0.0500837,0.00488983,0.957285 beta-lactamase_2500_D252I,beta-lactamase_2500_252,TEM-1,beta-lactamase_2500,P62593,0.957307,NO,252,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.94,,,,0.766,,B,1.59,1.16,,,67.83,OAO,-2.0965,0.361275,0.00575769,0.957307 beta-lactamase_0_T264L,beta-lactamase_0_264,TEM-1,beta-lactamase_0,P62593,0.957315,NO,264,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.0500837,0.0119399,0.957315 beta-lactamase_H285S,beta-lactamase_285,TEM-1,beta-lactamase,P62593,0.957329,NO,285,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-1.845,-3.307,1.462,5.64289,0.312,T,a,0.35,0.64,1.401,,72.73,BBH,-1.64567,0.221079,0.101555,0.957329 beta-lactamase_S201G,beta-lactamase_201,TEM-1,beta-lactamase,P62593,0.957329,NO,201,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.183,-2.39,1.207,4.85496,0.064,H,A,0.77,-0.07,4.045,,64.69,HPB,-1.451,0.221079,0.00198815,0.957329 kka2_1:2_S54Y,kka2_1:2_54,Kka2,kka2_1:2,P00552,0.957361,NO,54,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.471,-4.321,1.85,,0.408,S,b,0.27,1.01,0.393,,71.59,HPO,-2.259,0.295029,0.00782867,0.957361 kka2_1:8_V185R,kka2_1:8_185,Kka2,kka2_1:8,P00552,0.957361,NO,185,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.045,-4.178,3.133,,0.058,E,B,1.48,-0.49,1.234,,46.97,HHH,-1.184,0.100394,0.00367031,0.957361 kka2_1:8_V185R,kka2_1:8_185,Kka2,kka2_1:8,P00552,0.957361,NO,185,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.045,-4.178,3.133,,0.058,E,B,1.48,-0.49,1.234,,46.97,HHH,-1.184,0.100394,0.00367031,0.957361 beta-lactamase_39_Y103S,beta-lactamase_39_103,TEM-1,beta-lactamase_39,P62593,0.957363,NO,103,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-1.33,-3.594,2.264,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.0495842,0.00443048,0.957363 kka2_1:8_L70A,kka2_1:8_70,Kka2,kka2_1:8,P00552,0.957366,NO,70,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.017,-3.191,2.174,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.100394,0.00411884,0.957366 kka2_1:8_L70A,kka2_1:8_70,Kka2,kka2_1:8,P00552,0.957366,NO,70,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.017,-3.191,2.174,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.100394,0.00411884,0.957366 beta-lactamase_0_A282C,beta-lactamase_0_282,TEM-1,beta-lactamase_0,P62593,0.957367,NO,282,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.0500837,0.0449821,0.957367 PSD95pdz3_A382Y,PSD95pdz3_382,PSD95pdz3,PSD95pdz3,P31016,0.957376,NO,382,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.307,-3.844,2.537,5.30282,,,,,22.472,,,,PHO,-1.24167,0.0758425,0.000249256,0.957376 beta-lactamase_39_E169C,beta-lactamase_39_169,TEM-1,beta-lactamase_39,P62593,0.957401,NO,169,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.23,-5.088,3.858,,0.337,,A,1.04,1,15.633,15.633,73.08,PAH,-1.16533,0.0495842,0.00400994,0.957401 beta-lactamase_625_Q276F,beta-lactamase_625_276,TEM-1,beta-lactamase_625,P62593,0.957404,NO,276,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.213352,0.0191712,0.957404 beta-lactamase_625_K286F,beta-lactamase_625_286,TEM-1,beta-lactamase_625,P62593,0.957422,NO,286,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.213352,,0.957422 kka2_1:8_S105G,kka2_1:8_105,Kka2,kka2_1:8,P00552,0.957436,NO,105,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.945,-2.84,0.895,,0.056,S,B,0.27,-1.04,2.115,,65.53,PPB,-2.17033,0.100394,0.00847233,0.957436 kka2_1:8_S105G,kka2_1:8_105,Kka2,kka2_1:8,P00552,0.957436,NO,105,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.945,-2.84,0.895,,0.056,S,B,0.27,-1.04,2.115,,65.53,PPB,-2.17033,0.100394,0.00847233,0.957436 beta-lactamase_E145Y,beta-lactamase_145,TEM-1,beta-lactamase,P62593,0.95745,NO,145,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.357,-4.381,2.024,5.38104,0.545,H,A,0.52,0.79,2.124,,77.62,BAH,-2.069,0.221079,0.00553285,0.95745 kka2_1:8_D90G,kka2_1:8_90,Kka2,kka2_1:8,P00552,0.957454,NO,90,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.459,-3.503,1.044,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.100394,0.00583842,0.957454 kka2_1:8_D90G,kka2_1:8_90,Kka2,kka2_1:8,P00552,0.957454,NO,90,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.459,-3.503,1.044,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.100394,0.00583842,0.957454 beta-lactamase_39_I261S,beta-lactamase_39_261,TEM-1,beta-lactamase_39,P62593,0.957457,NO,261,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.0495842,0.0123091,0.957457 beta-lactamase_39_D212V,beta-lactamase_39_212,TEM-1,beta-lactamase_39,P62593,0.957461,NO,212,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.624,-3.608,1.984,,0.037,,b,0.75,-0.58,10.748,10.748,74.48,HAB,-1.77667,0.0495842,0.00644302,0.957461 beta-lactamase_39_K213Q,beta-lactamase_39_213,TEM-1,beta-lactamase_39,P62593,0.957501,NO,213,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.81,-2.028,0.218,,0.67,,A,2.34,0.29,2.648,,67.83,ABH,-1.57767,0.0495842,0.00610411,0.957501 beta-lactamase_156_D48Q,beta-lactamase_156_48,TEM-1,beta-lactamase_156,P62593,0.957535,NO,48,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.101,-3.681,2.58,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.111618,0.0027273,0.957535 beta-lactamase_2500_Q203I,beta-lactamase_2500_203,TEM-1,beta-lactamase_2500,P62593,0.957544,NO,203,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.168,-3.973,1.805,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.361275,0.00631514,0.957544 beta-lactamase_2500_H151C,beta-lactamase_2500_151,TEM-1,beta-lactamase_2500,P62593,0.957545,NO,151,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-2.96,-5.124,2.164,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.361275,0.00216946,0.957545 beta-lactamase_2500_R275W,beta-lactamase_2500_275,TEM-1,beta-lactamase_2500,P62593,0.95758,NO,275,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.361275,0.0141984,0.95758 beta-lactamase_0_N168L,beta-lactamase_0_168,TEM-1,beta-lactamase_0,P62593,0.957583,NO,168,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-1.029,-3.516,2.487,,0.113,G,A,0.61,-0.4,0.881,,44.41,HPA,-1.13233,0.0500837,0.00288667,0.957583 beta-lactamase_0_G240V,beta-lactamase_0_240,TEM-1,beta-lactamase_0,P62593,0.957585,NO,240,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.0500837,0.00591201,0.957585 kka2_1:4_R147V,kka2_1:4_147,Kka2,kka2_1:4,P00552,0.9576,NO,147,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.123,-3.865,2.742,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.168804,0.00549168,0.9576 kka2_1:8_P98T,kka2_1:8_98,Kka2,kka2_1:8,P00552,0.957604,NO,98,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.526,-2.967,1.441,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.100394,0.00622754,0.957604 kka2_1:8_P98T,kka2_1:8_98,Kka2,kka2_1:8,P00552,0.957604,NO,98,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.526,-2.967,1.441,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.100394,0.00622754,0.957604 beta-lactamase_39_A225L,beta-lactamase_39_225,TEM-1,beta-lactamase_39,P62593,0.957611,NO,225,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.845,-2.985,1.14,,1,T,B,0.46,-0.38,9.874,9.874,74.48,OHO,-1.39967,0.0495842,0.00465057,0.957611 beta-lactamase_39_R242D,beta-lactamase_39_242,TEM-1,beta-lactamase_39,P62593,0.957626,NO,242,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.0495842,0.00452879,0.957626 beta-lactamase_2500_D33C,beta-lactamase_2500_33,TEM-1,beta-lactamase_2500,P62593,0.957631,NO,33,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.321,-5.054,2.733,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.361275,0.00435556,0.957631 kka2_1:2_E199T,kka2_1:2_199,Kka2,kka2_1:2,P00552,0.957632,NO,199,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.234,-2.695,0.461,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.295029,0.00854122,0.957632 kka2_1:4_I141F,kka2_1:4_141,Kka2,kka2_1:4,P00552,0.957632,NO,141,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.495,-3.83,2.335,,0.068,H,A,0.48,-0.01,2.144,,92.05,BHA,-1.689,0.168804,0.00744745,0.957632 beta-lactamase_2500_V42L,beta-lactamase_2500_42,TEM-1,beta-lactamase_2500,P62593,0.957643,NO,42,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.564,-1.709,0.145,,0.017,E,B,0.44,-0.51,1.86,,63.99,BHO,-1.042,0.361275,0.00404515,0.957643 beta-lactamase_Y95W,beta-lactamase_95,TEM-1,beta-lactamase,P62593,0.957662,NO,95,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-1.715,-3.22,1.505,5.67068,0.122,,b,0.96,-0.37,2.341,,77.62,BHP,-2.16167,0.221079,0.00479449,0.957662 kka2_1:2_M178E,kka2_1:2_178,Kka2,kka2_1:2,P00552,0.957662,NO,178,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-3.206,-3.572,0.366,,0.554,.,b,0.55,0.68,3.152,,71.59,BHO,-2.154,0.295029,0.00717253,0.957662 beta-lactamase_2500_P217Q,beta-lactamase_2500_217,TEM-1,beta-lactamase_2500,P62593,0.957672,NO,217,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-2.062,-3.933,1.871,,0.496,I,A,0.52,-0.33,0.431,,74.48,OOH,-1.64333,0.361275,0.00463211,0.957672 beta-lactamase_0_R273P,beta-lactamase_0_273,TEM-1,beta-lactamase_0,P62593,0.957682,NO,273,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.314,-2.669,0.355,,0.564,H,A,1.2,1.57,20.248,20.248,73.78,ABP,-1.841,0.0500837,0.0077952,0.957682 kka2_1:4_T85E,kka2_1:4_85,Kka2,kka2_1:4,P00552,0.957696,NO,85,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.165,-2.512,0.347,,0.576,E,B,0.22,1.39,1.853,,71.59,HPA,-2.10133,0.168804,0.00634493,0.957696 kka2_1:8_C77V,kka2_1:8_77,Kka2,kka2_1:8,P00552,0.957697,NO,77,C,V,CV,Special,Hydrophobic,5.07,5.60847,0.538465,192,121,117,-4,108.5,140,31.5,-1.477,-2.554,1.077,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.100394,0.00441216,0.957697 kka2_1:8_C77V,kka2_1:8_77,Kka2,kka2_1:8,P00552,0.957697,NO,77,C,V,CV,Special,Hydrophobic,5.07,5.60847,0.538465,192,121,117,-4,108.5,140,31.5,-1.477,-2.554,1.077,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.100394,0.00441216,0.957697 gb1_A260M,gb1_260,gb1,gb1,P06654,0.957734,NO,260,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.486,-4.021,2.535,,,,,,,0.173,,9.6,HHP,-1.70967,0.177985,0.0055808,0.957734 gb1_I232S,gb1_232,gb1,gb1,P06654,0.957734,NO,232,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-2.175,-3.206,1.031,,,,,,,0.766,,44.87,HHH,-2.152,0.177985,0.00580459,0.957734 beta-lactamase_156_P65C,beta-lactamase_156_65,TEM-1,beta-lactamase_156,P62593,0.95774,NO,65,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.894,-5.01,4.116,,0.098,E,B,0.52,-0.62,0.623,,40.56,HOH,-1.03233,0.111618,0.00152776,0.95774 beta-lactamase_0_S241P,beta-lactamase_0_241,TEM-1,beta-lactamase_0,P62593,0.95776,NO,241,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.0500837,0.00452736,0.95776 kka2_1:4_W15R,kka2_1:4_15,Kka2,kka2_1:4,P00552,0.957779,NO,15,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-1.392,-4.195,2.803,,0.01,G,A,0.47,0.15,0.943,,52.27,HHH,-2.10533,0.168804,0.00585505,0.957779 beta-lactamase_156_E56C,beta-lactamase_156_56,TEM-1,beta-lactamase_156,P62593,0.957796,NO,56,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.043,-4.827,2.784,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.111618,0.00238534,0.957796 beta-lactamase_T139M,beta-lactamase_139,TEM-1,beta-lactamase,P62593,0.957798,NO,139,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.901,-4.659,2.758,5.69095,0.216,H,A,0.3,0.39,2.256,,77.62,PPH,-2.04667,0.221079,0.00441837,0.957798 beta-lactamase_0_P172S,beta-lactamase_0_172,TEM-1,beta-lactamase_0,P62593,0.957804,NO,172,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.998,-2.394,1.396,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.0500837,0.00312594,0.957804 beta-lactamase_39_M115K,beta-lactamase_39_115,TEM-1,beta-lactamase_39,P62593,0.957808,NO,115,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.389,-3.553,2.164,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.0495842,0.0034337,0.957808 beta-lactamase_2500_P172S,beta-lactamase_2500_172,TEM-1,beta-lactamase_2500,P62593,0.957826,NO,172,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.998,-2.394,1.396,,0.639,T,b,0.52,0.24,4.99,,74.48,HOP,-2.03067,0.361275,0.00312594,0.957826 beta-lactamase_625_G216P,beta-lactamase_625_216,TEM-1,beta-lactamase_625,P62593,0.957826,NO,216,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.477,-3.898,2.421,,0.437,I,A,0.29,-0.58,1.718,,74.48,HOO,-1.68067,0.213352,0.00639568,0.957826 beta-lactamase_156_Y103E,beta-lactamase_156_103,TEM-1,beta-lactamase_156,P62593,0.957846,NO,103,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-1.33,-3.564,2.234,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.111618,0.00443048,0.957846 kka2_1:4_P98H,kka2_1:4_98,Kka2,kka2_1:4,P00552,0.95787,NO,98,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.526,-4.763,3.237,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.168804,0.00622754,0.95787 kka2_1:4_E231M,kka2_1:4_231,Kka2,kka2_1:4,P00552,0.95788,NO,231,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.002,-4.813,2.811,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.168804,0.00732383,0.95788 Pab1_Y143S,Pab1_143,Pab1,Pab1,P04147,0.957882,NO,143,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-1.961,-3.412,1.451,,0.409,H,A,,0.3,,,,HHA,-1.39633,0.175299,0.00160364,0.957882 kka2_1:2_E160H,kka2_1:2_160,Kka2,kka2_1:2,P00552,0.957891,NO,160,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.683,-4.581,2.898,,0.989,G,A,1.04,2.28,3.948,,71.59,AAA,-1.36133,0.295029,0.00935762,0.957891 beta-lactamase_R91K,beta-lactamase_91,TEM-1,beta-lactamase,P62593,0.957894,NO,91,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.392,-2.505,1.113,5.92536,0.444,,B,0.68,0.96,1.318,,50.35,OBB,-1.73367,0.221079,0.00380226,0.957894 kka2_1:8_R140S,kka2_1:8_140,Kka2,kka2_1:8,P00552,0.957903,NO,140,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.351,-2.551,1.2,,0.12,H,A,0.16,0.2,2.874,,53.03,BBH,-1.885,0.100394,0.00430167,0.957903 kka2_1:8_R140S,kka2_1:8_140,Kka2,kka2_1:8,P00552,0.957903,NO,140,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.351,-2.551,1.2,,0.12,H,A,0.16,0.2,2.874,,53.03,BBH,-1.885,0.100394,0.00430167,0.957903 beta-lactamase_0_I277Y,beta-lactamase_0_277,TEM-1,beta-lactamase_0,P62593,0.957907,NO,277,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.0500837,0.0169305,0.957907 beta-lactamase_0_L89W,beta-lactamase_0_89,TEM-1,beta-lactamase_0,P62593,0.957937,NO,89,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.096,-5.236,4.14,,0.168,T,A,0.55,0.63,2.373,,64.34,PHO,-1.75767,0.0500837,0.00207068,0.957937 beta-lactamase_156_D212F,beta-lactamase_156_212,TEM-1,beta-lactamase_156,P62593,0.957955,NO,212,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.624,-4.334,2.71,,0.037,,b,0.75,-0.58,20.222,20.222,74.48,HAB,-1.77667,0.111618,0.00644302,0.957955 kka2_1:8_A144S,kka2_1:8_144,Kka2,kka2_1:8,P00552,0.957959,NO,144,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.859,-3.103,2.244,,,H,A,1.04,0.21,1.118,,52.65,BHB,-1.72933,0.100394,0.00231095,0.957959 kka2_1:8_A144S,kka2_1:8_144,Kka2,kka2_1:8,P00552,0.957959,NO,144,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.859,-3.103,2.244,,,H,A,1.04,0.21,1.118,,52.65,BHB,-1.72933,0.100394,0.00231095,0.957959 kka2_1:4_P12D,kka2_1:4_12,Kka2,kka2_1:4,P00552,0.957964,NO,12,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.853,-3.54,2.687,,,,B,0.52,1.25,0.843,,48.11,POH,-1.80767,0.168804,0.00500011,0.957964 beta-lactamase_0_G253T,beta-lactamase_0_253,TEM-1,beta-lactamase_0,P62593,0.95798,NO,253,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.0500837,0.00786358,0.95798 beta-lactamase_2500_H287Q,beta-lactamase_2500_287,TEM-1,beta-lactamase_2500,P62593,0.957988,NO,287,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,,,,,,,,,,,,,BBH,-1.111,0.361275,,0.957988 PSD95pdz3_G345T,PSD95pdz3_345,PSD95pdz3,PSD95pdz3,P31016,0.958002,NO,345,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.008,-3.328,2.32,4.32868,,,,,13.165,,,,OOO,-1.084,0.0758425,0.000771806,0.958002 beta-lactamase_2500_G194C,beta-lactamase_2500_194,TEM-1,beta-lactamase_2500,P62593,0.958007,NO,194,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.396,-5.097,3.701,,0.276,S,b,0.29,0.36,3.593,,67.83,POA,-1.832,0.361275,0.00392163,0.958007 beta-lactamase_2500_K53Y,beta-lactamase_2500_53,TEM-1,beta-lactamase_2500,P62593,0.958028,NO,53,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-2.313,-4.187,1.874,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.361275,0.00383383,0.958028 beta-lactamase_39_M153E,beta-lactamase_39_153,TEM-1,beta-lactamase_39,P62593,0.958038,NO,153,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-3.193,-3.818,0.625,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.0495842,0.00509109,0.958038 PSD95pdz3_G383N,PSD95pdz3_383,PSD95pdz3,PSD95pdz3,P31016,0.958083,NO,383,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.008,-3.13,2.122,5.17213,,,,,20.5325,,,,HOP,-1.338,0.0758425,0.000233044,0.958083 kka2_1:8_K138E,kka2_1:8_138,Kka2,kka2_1:8,P00552,0.95809,NO,138,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-2.5,-1.783,-0.717,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.100394,0.00628542,0.95809 kka2_1:8_K138E,kka2_1:8_138,Kka2,kka2_1:8,P00552,0.95809,NO,138,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-2.5,-1.783,-0.717,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.100394,0.00628542,0.95809 beta-lactamase_K32N,beta-lactamase_32,TEM-1,beta-lactamase,P62593,0.958127,NO,32,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.984,-2.965,0.981,5.55842,0.563,H,A,1.82,0.34,1.754,,73.08,HBA,-2.04233,0.221079,0.00401283,0.958127 PSD95pdz3_R368T,PSD95pdz3_368,PSD95pdz3,PSD95pdz3,P31016,0.958128,NO,368,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.582,-3.103,1.521,6.13355,,,,,18.1818,,,,HBP,-1.50033,0.0758425,0.000451517,0.958128 beta-lactamase_156_L146Y,beta-lactamase_156_146,TEM-1,beta-lactamase_156,P62593,0.958141,NO,146,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.462,-3.821,2.359,,0.007,H,A,0.55,-0.56,1.578,,64.69,AHP,-1.656,0.111618,0.00474542,0.958141 beta-lactamase_625_R202Y,beta-lactamase_625_202,TEM-1,beta-lactamase_625,P62593,0.958147,NO,202,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.292,-4.182,2.89,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.213352,0.00321899,0.958147 beta-lactamase_156_V101G,beta-lactamase_156_101,TEM-1,beta-lactamase_156,P62593,0.95815,NO,101,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.295,-3.721,2.426,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.111618,0.00374492,0.95815 beta-lactamase_0_D207S,beta-lactamase_0_207,TEM-1,beta-lactamase_0,P62593,0.958153,NO,207,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.064,-2.656,0.592,,0.409,H,A,0.75,0.12,5.277,,77.62,HAH,-1.77033,0.0500837,0.00592942,0.958153 PSD95pdz3_S339C,PSD95pdz3_339,PSD95pdz3,PSD95pdz3,P31016,0.958158,NO,339,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.519,-4.319,2.8,5.34493,,,,,12.2167,,,,HPH,-1.55767,0.0758425,0.00084982,0.958158 beta-lactamase_156_V72I,beta-lactamase_156_72,TEM-1,beta-lactamase_156,P62593,0.958176,NO,72,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.658,-3.311,1.653,,,H,A,0.44,-1.03,1.92,,65.73,BHH,-1.32167,0.111618,0.00501194,0.958176 beta-lactamase_39_A225H,beta-lactamase_39_225,TEM-1,beta-lactamase_39,P62593,0.958196,NO,225,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.845,-3.109,1.264,,1,T,B,0.46,-0.38,9.874,9.874,74.48,OHO,-1.39967,0.0495842,0.00465057,0.958196 beta-lactamase_0_L192K,beta-lactamase_0_192,TEM-1,beta-lactamase_0,P62593,0.958203,NO,192,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.254,-3.803,2.549,,0.095,H,A,0.55,0.35,1.756,,60.14,HHP,-1.41833,0.0500837,0.00558728,0.958203 beta-lactamase_0_E145D,beta-lactamase_0_145,TEM-1,beta-lactamase_0,P62593,0.958279,NO,145,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.357,-3.52,1.163,,0.545,H,A,1.04,0.79,1.199,,77.62,BAH,-2.069,0.0500837,0.00553285,0.958279 beta-lactamase_39_L120Q,beta-lactamase_39_120,TEM-1,beta-lactamase_39,P62593,0.958291,NO,120,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.044,-4.124,3.08,,,H,A,0.55,-1.13,22.254,22.254,64.69,AHO,-1.13633,0.0495842,0.00143563,0.958291 beta-lactamase_39_L120N,beta-lactamase_39_120,TEM-1,beta-lactamase_39,P62593,0.958335,NO,120,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.044,-4.027,2.983,,,H,A,0.55,-1.13,22.254,22.254,64.69,AHO,-1.13633,0.0495842,0.00143563,0.958335 beta-lactamase_P25L,beta-lactamase_25,TEM-1,beta-lactamase,P62593,0.958344,NO,25,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.526,-3.586,2.06,5.6134,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.221079,0.00347571,0.958344 beta-lactamase_39_M180C,beta-lactamase_39_180,TEM-1,beta-lactamase_39,P62593,0.958348,NO,180,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-2.795,-4.786,1.991,,0.242,,B,0.55,-0.94,3.579,,77.62,PHO,-1.56433,0.0495842,0.00552048,0.958348 beta-lactamase_625_I206N,beta-lactamase_625_206,TEM-1,beta-lactamase_625,P62593,0.958351,NO,206,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-2.429,-3.933,1.504,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.213352,0.00528934,0.958351 gb1_K230Y,gb1_230,gb1,gb1,P06654,0.958361,NO,230,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.701,-1.746,0.045,,,,,,,0.166,,11.83,HBH,-1.52867,0.177985,0.00331703,0.958361 beta-lactamase_0_L284M,beta-lactamase_0_284,TEM-1,beta-lactamase_0,P62593,0.958363,NO,284,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.981,,,,0.848,H,A,2.89,0.67,4.544,,77.62,PHH,-1.82133,0.0500837,0.0686156,0.958363 beta-lactamase_625_V214M,beta-lactamase_625_214,TEM-1,beta-lactamase_625,P62593,0.958382,NO,214,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.299,-4.251,2.952,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.213352,0.00628442,0.958382 beta-lactamase_156_L218N,beta-lactamase_156_218,TEM-1,beta-lactamase_156,P62593,0.958385,NO,218,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.391,-3.851,2.46,,,I,b,0.55,-0.53,17.202,17.202,74.48,OHH,-1.58867,0.111618,0.00618274,0.958385 beta-lactamase_0_Q37E,beta-lactamase_0_37,TEM-1,beta-lactamase_0,P62593,0.958388,NO,37,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.134,-2.427,0.293,,0.613,H,A,0.64,1.98,4.001,,73.08,APH,-2.06967,0.0500837,0.00425833,0.958388 beta-lactamase_0_D129A,beta-lactamase_0_129,TEM-1,beta-lactamase_0,P62593,0.958398,NO,129,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.816,-3.3,2.484,,,,B,0.75,-0.69,2.66,,34.97,PAP,-0.818,0.0500837,0.00109178,0.958398 kka2_1:2_M197I,kka2_1:2_197,Kka2,kka2_1:2,P00552,0.958427,NO,197,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.707,-1.88,0.173,,0.121,E,B,0.55,-1.19,2.097,,65.53,HHH,-1.847,0.295029,0.00921295,0.958427 beta-lactamase_A16I,beta-lactamase_16,TEM-1,beta-lactamase,P62593,0.958437,NO,16,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,,-3.646,1.711,,,,,,,,,,HHH,,0.221079,0.00245392,0.958437 beta-lactamase_F14A,beta-lactamase_14,TEM-1,beta-lactamase,P62593,0.958437,NO,14,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-2.736,-3.097,0.361,,,,,,,1.537,,93.01,HHH,-2.26133,0.221079,0.00277095,0.958437 beta-lactamase_F70V,beta-lactamase_70,TEM-1,beta-lactamase,P62593,0.958437,NO,70,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.169,-2.579,1.41,5.42055,,H,A,1.1,-1.34,1.14,,63.99,PHB,-0.980667,0.221079,0.00193499,0.958437 beta-lactamase_H24F,beta-lactamase_24,TEM-1,beta-lactamase,P62593,0.958437,NO,24,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-2.481,-4.152,1.671,5.82767,,,,,,2.708,,93.01,HBO,-1.85167,0.221079,0.00238894,0.958437 beta-lactamase_T262N,beta-lactamase_262,TEM-1,beta-lactamase,P62593,0.958437,NO,262,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.332,-3.553,2.221,5.06002,0.108,E,B,0.3,-0.55,1.423,,67.83,PPO,-2.081,0.221079,0.00853516,0.958437 E1_Ubiquitin_A46C,E1_Ubiquitin_46,Uba1,E1_Ubiquitin,P0CG63,0.958444,NO,46,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.367,-4.52,3.153,,0.398,T,L,,-0.8,,,,HHO,-1.17167,0.18783,0.004233,0.958444 E1_Ubiquitin_G47Q,E1_Ubiquitin_47,Uba1,E1_Ubiquitin,P0CG63,0.958444,NO,47,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.999,-2.377,1.378,,0.057,T,l,,-1.21,,,,HOB,-1.195,0.18783,0.00142261,0.958444 beta-lactamase_2500_E175F,beta-lactamase_2500_175,TEM-1,beta-lactamase_2500,P62593,0.958447,NO,175,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.336,-4.36,2.024,,0.551,,A,1.04,1.05,5.316,,77.62,AAB,-1.31233,0.361275,0.00482205,0.958447 Pab1_G167E,Pab1_167,Pab1,Pab1,P04147,0.958456,NO,167,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.223,-3.524,2.301,,0.195,S,g,,0.03,,,,BOH,-1.25133,0.175299,0.00146449,0.958456 beta-lactamase_0_K109Q,beta-lactamase_0_109,TEM-1,beta-lactamase_0,P62593,0.958482,NO,109,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.734,-2.855,1.121,,0.787,G,A,2.34,2.21,15.473,15.473,72.73,ABB,-1.63333,0.0500837,0.00462493,0.958482 beta-lactamase_625_R41W,beta-lactamase_625_41,TEM-1,beta-lactamase_625,P62593,0.958485,NO,41,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-0.942,-5.348,4.406,,0.321,E,B,1.2,-0.07,1.186,,65.03,HBH,-1.30267,0.213352,0.00123327,0.958485 beta-lactamase_39_A183C,beta-lactamase_39_183,TEM-1,beta-lactamase_39,P62593,0.958486,NO,183,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.231,-4.684,3.453,,0.155,H,A,0.46,-0.91,1.237,,77.62,HHH,-1.53367,0.0495842,0.00296631,0.958486 beta-lactamase_0_R189D,beta-lactamase_0_189,TEM-1,beta-lactamase_0,P62593,0.958516,NO,189,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.844,-2.871,1.027,,0.278,H,A,1.2,1.01,12.11,12.11,72.73,HBB,-1.668,0.0500837,0.0050699,0.958516 beta-lactamase_G90R,beta-lactamase_90,TEM-1,beta-lactamase,P62593,0.958523,NO,90,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-2.091,-3.098,1.007,5.51991,0.598,T,A,0.23,0.32,1.791,,77.62,HOB,-1.52633,0.221079,0.00490273,0.958523 beta-lactamase_39_V101Q,beta-lactamase_39_101,TEM-1,beta-lactamase_39,P62593,0.958526,NO,101,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.295,-4.106,2.811,,0.342,,B,0.44,0,2.96,,73.08,HHA,-1.54367,0.0495842,0.00374492,0.958526 beta-lactamase_39_M153C,beta-lactamase_39_153,TEM-1,beta-lactamase_39,P62593,0.958542,NO,153,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-3.193,-4.79,1.597,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.0495842,0.00509109,0.958542 beta-lactamase_0_Q97A,beta-lactamase_0_97,TEM-1,beta-lactamase_0,P62593,0.95856,NO,97,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.072,-2.26,0.188,,0.823,G,A,0.64,2.42,16.954,16.954,77.62,PPP,-2.43833,0.0500837,0.0045116,0.95856 beta-lactamase_39_V117W,beta-lactamase_39_117,TEM-1,beta-lactamase_39,P62593,0.958565,NO,117,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.53,-5.228,3.698,,,H,A,0.44,-0.34,1.182,,65.03,PHB,-1.741,0.0495842,0.00467906,0.958565 beta-lactamase_0_G216C,beta-lactamase_0_216,TEM-1,beta-lactamase_0,P62593,0.958581,NO,216,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.477,-5.186,3.709,,0.437,I,A,0.29,-0.58,0.834,,74.48,HOO,-1.68067,0.0500837,0.00639568,0.958581 beta-lactamase_0_S51G,beta-lactamase_0_51,TEM-1,beta-lactamase_0,P62593,0.958603,NO,51,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.526,-2.569,1.043,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.0500837,0.00504821,0.958603 beta-lactamase_39_D83I,beta-lactamase_39_83,TEM-1,beta-lactamase_39,P62593,0.958608,NO,83,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.066,-4.081,3.015,,0.354,H,A,0.75,0.22,0.752,,48.95,HAH,-1.34733,0.0495842,0.00205968,0.958608 PSD95pdz3_L349G,PSD95pdz3_349,PSD95pdz3,PSD95pdz3,P31016,0.958666,NO,349,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.347,-3.49,2.143,5.14696,,,,,24.6438,,,,AHP,-1.37667,0.0758425,0.00071841,0.958666 beta-lactamase_0_I93F,beta-lactamase_0_93,TEM-1,beta-lactamase_0,P62593,0.958683,NO,93,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.401,-3.88,2.479,,0.128,E,B,0.48,0.44,1.266,,67.83,BHB,-1.873,0.0500837,0.00527066,0.958683 beta-lactamase_A40S,beta-lactamase_40,TEM-1,beta-lactamase,P62593,0.958699,NO,40,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.402,-3.164,1.762,4.9697,0.155,S,B,1.2,0.21,1.714,,73.78,OHB,-1.40267,0.221079,0.00490026,0.958699 beta-lactamase_2500_Q203V,beta-lactamase_2500_203,TEM-1,beta-lactamase_2500,P62593,0.958703,NO,203,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.168,-3.605,1.437,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.361275,0.00631514,0.958703 beta-lactamase_39_V101A,beta-lactamase_39_101,TEM-1,beta-lactamase_39,P62593,0.958706,NO,101,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.295,-3.114,1.819,,0.342,,B,0.44,0,2.96,,73.08,HHA,-1.54367,0.0495842,0.00374492,0.958706 beta-lactamase_2500_A222C,beta-lactamase_2500_222,TEM-1,beta-lactamase_2500,P62593,0.958718,NO,222,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.103,-4.939,2.836,,0.233,H,A,0.46,-0.25,0.379,,77.62,PHH,-1.63733,0.361275,0.00466094,0.958718 kka2_1:4_A229G,kka2_1:4_229,Kka2,kka2_1:4,P00552,0.958732,NO,229,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.739,-2.492,0.753,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.168804,0.00942138,0.958732 beta-lactamase_E175G,beta-lactamase_175,TEM-1,beta-lactamase,P62593,0.958743,NO,175,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.336,-3.483,1.147,6.0311,0.551,,A,0.75,1.05,5.316,,77.62,AAB,-1.31233,0.221079,0.00482205,0.958743 beta-lactamase_39_L146Y,beta-lactamase_39_146,TEM-1,beta-lactamase_39,P62593,0.958749,NO,146,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.462,-3.821,2.359,,0.007,H,A,0.55,-0.56,1.953,,64.69,AHP,-1.656,0.0495842,0.00474542,0.958749 kka2_1:8_A150F,kka2_1:8_150,Kka2,kka2_1:8,P00552,0.958765,NO,150,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.949,-4.228,3.279,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.100394,0.0045009,0.958765 kka2_1:8_A150F,kka2_1:8_150,Kka2,kka2_1:8,P00552,0.958765,NO,150,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.949,-4.228,3.279,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.100394,0.0045009,0.958765 beta-lactamase_P172G,beta-lactamase_172,TEM-1,beta-lactamase,P62593,0.958805,NO,172,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.998,-3.35,2.352,5.98941,0.639,T,b,1.1,0.24,2.087,,74.48,HOP,-2.03067,0.221079,0.00312594,0.958805 beta-lactamase_39_I206H,beta-lactamase_39_206,TEM-1,beta-lactamase_39,P62593,0.958812,NO,206,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-2.429,-4.842,2.413,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.0495842,0.00528934,0.958812 beta-lactamase_A266H,beta-lactamase_266,TEM-1,beta-lactamase,P62593,0.958825,NO,266,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.369,-4.796,3.427,5.02057,0.175,S,B,0.52,0.07,1.832,,64.34,PHP,-2.08567,0.221079,0.0140785,0.958825 kka2_1:8_L184R,kka2_1:8_184,Kka2,kka2_1:8,P00552,0.958835,NO,184,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.496,-2.591,1.095,,0.489,E,B,0.55,-0.06,4.495,,63.26,AHH,-1.24833,0.100394,0.00518742,0.958835 kka2_1:8_L184R,kka2_1:8_184,Kka2,kka2_1:8,P00552,0.958835,NO,184,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.496,-2.591,1.095,,0.489,E,B,0.55,-0.06,4.495,,63.26,AHH,-1.24833,0.100394,0.00518742,0.958835 beta-lactamase_0_V78Y,beta-lactamase_0_78,TEM-1,beta-lactamase_0,P62593,0.958842,NO,78,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.459,-4.112,2.653,,,H,A,0.44,-0.47,16.615,16.615,63.64,HHH,-1.17833,0.0500837,0.00492501,0.958842 beta-lactamase_F149I,beta-lactamase_149,TEM-1,beta-lactamase,P62593,0.958859,NO,149,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.299,-3.576,2.277,5.54789,0.195,H,A,1.1,0.11,1.863,,63.99,HHH,-1.46067,0.221079,0.00418462,0.958859 kka2_1:4_A65S,kka2_1:4_65,Kka2,kka2_1:4,P00552,0.95888,NO,65,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.744,-2.937,1.193,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.168804,0.00709258,0.95888 beta-lactamase_0_A235E,beta-lactamase_0_235,TEM-1,beta-lactamase_0,P62593,0.958886,NO,235,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.266,-3.558,2.292,,0.32,E,B,0.46,-0.86,2.261,,50,OHO,-0.89,0.0500837,0.00493474,0.958886 beta-lactamase_2500_Q276N,beta-lactamase_2500_276,TEM-1,beta-lactamase_2500,P62593,0.958888,NO,276,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.361275,0.0191712,0.958888 beta-lactamase_H24I,beta-lactamase_24,TEM-1,beta-lactamase,P62593,0.958899,NO,24,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-2.481,-3.874,1.393,5.82767,,,,,,2.708,,93.01,HBO,-1.85167,0.221079,0.00238894,0.958899 PSD95pdz3_G383C,PSD95pdz3_383,PSD95pdz3,PSD95pdz3,P31016,0.958899,NO,383,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.008,-4.769,3.761,5.17213,,,,,20.5325,,,,HOP,-1.338,0.0758425,0.000233044,0.958899 PSD95pdz3_G351D,PSD95pdz3_351,PSD95pdz3,PSD95pdz3,P31016,0.958913,NO,351,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.008,-3.15,2.142,5.44798,,,,,20.7625,,,,POA,-1.37133,0.0758425,0.000691282,0.958913 beta-lactamase_2500_R275D,beta-lactamase_2500_275,TEM-1,beta-lactamase_2500,P62593,0.958933,NO,275,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.361275,0.0141984,0.958933 beta-lactamase_I275L,beta-lactamase_275,TEM-1,beta-lactamase,P62593,0.958948,NO,275,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.397,-2.022,0.625,5.3999,0.015,H,A,1,-0.52,0.836,,62.59,PHH,-1.541,0.221079,0.0141984,0.958948 beta-lactamase_2500_I125L,beta-lactamase_2500_125,TEM-1,beta-lactamase_2500,P62593,0.958968,NO,125,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.441,-1.939,0.498,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.361275,0.00383964,0.958968 beta-lactamase_39_E35G,beta-lactamase_39_35,TEM-1,beta-lactamase_39,P62593,0.958973,NO,35,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-0.869,-3.356,2.487,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.0495842,0.00174441,0.958973 beta-lactamase_39_M180F,beta-lactamase_39_180,TEM-1,beta-lactamase_39,P62593,0.95898,NO,180,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-2.795,-3.981,1.186,,0.242,,B,0.55,-0.94,3.579,,77.62,PHO,-1.56433,0.0495842,0.00552048,0.95898 beta-lactamase_625_G114H,beta-lactamase_625_114,TEM-1,beta-lactamase_625,P62593,0.958981,NO,114,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.094,-4.665,3.571,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.213352,0.00224919,0.958981 gb1_T243V,gb1_243,gb1,gb1,P06654,0.958985,NO,243,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.415,-2.89,1.475,,,,,,,1.083,,37.28,PPP,-1.43233,0.177985,0.00308687,0.958985 kka2_1:8_S104R,kka2_1:8_104,Kka2,kka2_1:8,P00552,0.959003,NO,104,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.436,-3.063,1.627,,0.536,T,A,0.27,-1.11,1.689,,63.64,HPP,-1.91433,0.100394,0.00555207,0.959003 kka2_1:8_S104R,kka2_1:8_104,Kka2,kka2_1:8,P00552,0.959003,NO,104,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.436,-3.063,1.627,,0.536,T,A,0.27,-1.11,1.689,,63.64,HPP,-1.91433,0.100394,0.00555207,0.959003 beta-lactamase_X287T,beta-lactamase_287,TEM-1,beta-lactamase,P62593,0.959009,NO,287,X,T,XT,Stop,Polar,5.71,5.6,-0.11,,132.5,119,-13,141.9,116.1,-25.8,,,,,,,,,,,,,HXO,-1.111,0.221079,,0.959009 beta-lactamase_39_L55P,beta-lactamase_39_55,TEM-1,beta-lactamase_39,P62593,0.959034,NO,55,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.86,-4.226,2.366,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.0495842,0.00403741,0.959034 beta-lactamase_39_M180P,beta-lactamase_39_180,TEM-1,beta-lactamase_39,P62593,0.959036,NO,180,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-2.795,-2.76,-0.035,,0.242,,B,0.55,-0.94,3.579,,77.62,PHO,-1.56433,0.0495842,0.00552048,0.959036 kka2_1:4_W24R,kka2_1:4_24,Kka2,kka2_1:4,P00552,0.959038,NO,24,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-1.779,-4.308,2.529,,0.477,E,B,1.51,-0.21,2.666,,56.06,AHH,-2.24467,0.168804,0.00631564,0.959038 beta-lactamase_156_V78E,beta-lactamase_156_78,TEM-1,beta-lactamase_156,P62593,0.959041,NO,78,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.459,-3.911,2.452,,,H,A,0.44,-0.47,1.132,,63.64,HHH,-1.17833,0.111618,0.00492501,0.959041 kka2_1:4_P128W,kka2_1:4_128,Kka2,kka2_1:4,P00552,0.959062,NO,128,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.922,-3.525,1.603,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.168804,0.00774689,0.959062 beta-lactamase_39_T179C,beta-lactamase_39_179,TEM-1,beta-lactamase_39,P62593,0.95908,NO,179,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.085,-4.712,3.627,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.0495842,0.00226045,0.95908 beta-lactamase_0_A124C,beta-lactamase_0_124,TEM-1,beta-lactamase_0,P62593,0.959085,NO,124,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.181,-4.594,3.413,,,H,A,0.46,-0.9,1.876,,64.34,HHH,-1.152,0.0500837,0.00481399,0.959085 beta-lactamase_K190L,beta-lactamase_190,TEM-1,beta-lactamase,P62593,0.959085,NO,190,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.994,-3.527,1.533,5.49163,0.371,H,A,1.82,0.16,29.753,29.753,77.62,BBH,-1.64167,0.221079,0.00574527,0.959085 beta-lactamase_39_Q88C,beta-lactamase_39_88,TEM-1,beta-lactamase_39,P62593,0.959091,NO,88,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.086,-5.138,3.052,,0.807,,B,0.64,2.03,11.108,11.108,77.62,APH,-1.53433,0.0495842,0.00504167,0.959091 kka2_1:8_H135M,kka2_1:8_135,Kka2,kka2_1:8,P00552,0.959096,NO,135,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-1.331,-4.614,3.283,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.100394,0.00532566,0.959096 kka2_1:8_H135M,kka2_1:8_135,Kka2,kka2_1:8,P00552,0.959096,NO,135,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-1.331,-4.614,3.283,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.100394,0.00532566,0.959096 beta-lactamase_39_G85P,beta-lactamase_39_85,TEM-1,beta-lactamase_39,P62593,0.959102,NO,85,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.011,-3.891,2.88,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.0495842,0.00252173,0.959102 beta-lactamase_39_M180V,beta-lactamase_39_180,TEM-1,beta-lactamase_39,P62593,0.959109,NO,180,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-2.795,-3.273,0.478,,0.242,,B,0.55,-0.94,3.579,,77.62,PHO,-1.56433,0.0495842,0.00552048,0.959109 beta-lactamase_156_R81H,beta-lactamase_156_81,TEM-1,beta-lactamase_156,P62593,0.959115,NO,81,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.466,-4.464,2.998,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.111618,0.00499763,0.959115 beta-lactamase_625_V42Y,beta-lactamase_625_42,TEM-1,beta-lactamase_625,P62593,0.959117,NO,42,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.564,-4.12,2.556,,0.017,E,B,0.44,-0.51,2.576,,63.99,BHO,-1.042,0.213352,0.00404515,0.959117 beta-lactamase_0_I261W,beta-lactamase_0_261,TEM-1,beta-lactamase_0,P62593,0.959145,NO,261,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.0500837,0.0123091,0.959145 beta-lactamase_0_C75Y,beta-lactamase_0_75,TEM-1,beta-lactamase_0,P62593,0.959166,NO,75,C,Y,CY,Special,Hydrophobic,5.07,5.66,0.59,194,121,181,60,108.5,193.6,85.1,-1.245,-4.265,3.02,,,H,A,0.46,-0.87,2.256,,50,HOO,-1.24333,0.0500837,0.0034616,0.959166 beta-lactamase_625_E46G,beta-lactamase_625_46,TEM-1,beta-lactamase_625,P62593,0.959174,NO,46,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.94,-2.778,0.838,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.213352,0.00427568,0.959174 beta-lactamase_H5T,beta-lactamase_5,TEM-1,beta-lactamase,P62593,0.959186,NO,5,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-2.698,-3.561,0.863,,,,,,,1.865,,72.73,PBH,-2.36967,0.221079,0.00292712,0.959186 beta-lactamase_N173V,beta-lactamase_173,TEM-1,beta-lactamase,P62593,0.959186,NO,173,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-2.663,-3.738,1.075,7.02497,1.044,T,l,0.09,1.25,1.88,,77.62,OPA,-1.46633,0.221079,0.0033769,0.959186 beta-lactamase_R273S,beta-lactamase_273,TEM-1,beta-lactamase,P62593,0.959186,NO,273,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.314,-3.326,1.012,,0.564,H,A,1.2,1.57,,,73.78,ABP,-1.841,0.221079,0.0077952,0.959186 gb1_T243N,gb1_243,gb1,gb1,P06654,0.959192,NO,243,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.415,-3.388,1.973,,,,,,,1.083,,37.28,PPP,-1.43233,0.177985,0.00308687,0.959192 beta-lactamase_156_D252K,beta-lactamase_156_252,TEM-1,beta-lactamase_156,P62593,0.959195,NO,252,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.94,-3.575,1.635,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.111618,0.00575769,0.959195 beta-lactamase_0_P224C,beta-lactamase_0_224,TEM-1,beta-lactamase_0,P62593,0.959219,NO,224,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.893,-5.08,4.187,,0.383,,B,0.52,-0.3,3.587,,74.48,HOH,-1.26433,0.0500837,0.00189564,0.959219 Pab1_L191A,Pab1_191,Pab1,Pab1,P04147,0.95923,NO,191,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.2,-2.97,1.77,,0.204,E,B,,2.24,,,,HHP,-1.20133,0.175299,0.000583797,0.95923 beta-lactamase_0_G142Q,beta-lactamase_0_142,TEM-1,beta-lactamase_0,P62593,0.959246,NO,142,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.707,-4.087,3.38,,0.034,,p,0.29,-0.64,1.947,,64.69,OOO,-0.834,0.0500837,0.00060149,0.959246 beta-lactamase_2500_Q203D,beta-lactamase_2500_203,TEM-1,beta-lactamase_2500,P62593,0.959262,NO,203,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.168,-2.512,0.344,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.361275,0.00631514,0.959262 Pab1_D144R,Pab1_144,Pab1,Pab1,P04147,0.959266,NO,144,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.189,-3.656,2.467,,0.616,H,A,,0.6,,,,HAP,-1.40567,0.175299,0.00121131,0.959266 beta-lactamase_R92F,beta-lactamase_92,TEM-1,beta-lactamase,P62593,0.959273,NO,92,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.718,-4.33,2.612,5.65832,0.479,E,B,0.91,1.36,3.069,,65.38,BBH,-1.50367,0.221079,0.00429626,0.959273 kka2_1:8_E182V,kka2_1:8_182,Kka2,kka2_1:8,P00552,0.959273,NO,182,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.516,-3.667,2.151,,0.326,,B,1.52,0.75,2.568,,65.53,OAA,-1.806,0.100394,0.00641548,0.959273 kka2_1:8_E182V,kka2_1:8_182,Kka2,kka2_1:8,P00552,0.959273,NO,182,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.516,-3.667,2.151,,0.326,,B,1.52,0.75,2.568,,65.53,OAA,-1.806,0.100394,0.00641548,0.959273 beta-lactamase_39_D48Q,beta-lactamase_39_48,TEM-1,beta-lactamase_39,P62593,0.95928,NO,48,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.101,-3.681,2.58,,0.189,E,B,0.75,0.21,0.735,,50.35,HAH,-1.62467,0.0495842,0.0027273,0.95928 beta-lactamase_156_D252C,beta-lactamase_156_252,TEM-1,beta-lactamase_156,P62593,0.95929,NO,252,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.111618,0.00575769,0.95929 beta-lactamase_A182E,beta-lactamase_182,TEM-1,beta-lactamase,P62593,0.959292,NO,182,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.777,-2.345,0.568,4.98609,0.136,H,A,0.52,-0.66,2.032,,93.01,OHH,-1.27367,0.221079,0.00559099,0.959292 beta-lactamase_Q204R,beta-lactamase_204,TEM-1,beta-lactamase,P62593,0.959292,NO,204,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-1.382,-2.322,0.94,5.46394,0.204,H,A,0.12,0.09,1.707,,66.08,PPH,-1.49067,0.221079,0.00364106,0.959292 beta-lactamase_0_R257W,beta-lactamase_0_257,TEM-1,beta-lactamase_0,P62593,0.959293,NO,257,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.0500837,0.00756629,0.959293 beta-lactamase_156_I206F,beta-lactamase_156_206,TEM-1,beta-lactamase_156,P62593,0.959294,NO,206,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-2.429,-4.165,1.736,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.111618,0.00528934,0.959294 kka2_1:8_L102C,kka2_1:8_102,Kka2,kka2_1:8,P00552,0.959301,NO,102,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.804,-4.689,3.885,,,T,A,1.59,-1.17,0.97,,42.42,AHH,-1.398,0.100394,0.00201332,0.959301 kka2_1:8_L102C,kka2_1:8_102,Kka2,kka2_1:8,P00552,0.959301,NO,102,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.804,-4.689,3.885,,,T,A,1.59,-1.17,0.97,,42.42,AHH,-1.398,0.100394,0.00201332,0.959301 beta-lactamase_39_E119H,beta-lactamase_39_119,TEM-1,beta-lactamase_39,P62593,0.95931,NO,119,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.412,-4.521,3.109,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.0495842,0.00386966,0.95931 beta-lactamase_2500_D33I,beta-lactamase_2500_33,TEM-1,beta-lactamase_2500,P62593,0.959326,NO,33,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.321,-3.065,0.744,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.361275,0.00435556,0.959326 Pab1_D136E,Pab1_136,Pab1,Pab1,P04147,0.959356,NO,136,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.602,-3.072,1.47,,,,,,,,,,OAH,-1.42367,0.175299,0.00227029,0.959356 beta-lactamase_39_M184F,beta-lactamase_39_184,TEM-1,beta-lactamase_39,P62593,0.959362,NO,184,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.593,-2.94,1.347,,,H,A,0.55,-0.87,2.893,,62.94,HHH,-1.41,0.0495842,0.00356019,0.959362 beta-lactamase_0_W208F,beta-lactamase_0_208,TEM-1,beta-lactamase_0,P62593,0.959383,NO,208,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-0.818,-3.392,2.574,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.0500837,0.00126609,0.959383 PSD95pdz3_E331M,PSD95pdz3_331,PSD95pdz3,PSD95pdz3,P31016,0.959383,NO,331,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.404,-4.387,2.983,5.86289,,,,,51.8889,,,,OAA,-1.22533,0.0758425,0.000950134,0.959383 beta-lactamase_0_G243W,beta-lactamase_0_243,TEM-1,beta-lactamase_0,P62593,0.959389,NO,243,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.0500837,0.00464034,0.959389 beta-lactamase_156_A268Q,beta-lactamase_156_268,TEM-1,beta-lactamase_156,P62593,0.959394,NO,268,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.111618,0.0102525,0.959394 beta-lactamase_W163A,beta-lactamase_163,TEM-1,beta-lactamase,P62593,0.959433,NO,163,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-1.843,-3.41,1.567,6.2765,0.467,,B,1.22,-0.5,3.642,,63.99,BHA,-1.269,0.221079,0.00418955,0.959433 Pab1_T159D,Pab1_159,Pab1,Pab1,P04147,0.959446,NO,159,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.445,-3.438,1.993,,,,,,,2.531,,79.03,HPA,-1.19467,0.175299,0.00133849,0.959446 beta-lactamase_625_A170Y,beta-lactamase_625_170,TEM-1,beta-lactamase_625,P62593,0.959448,NO,170,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.237,-4.057,2.82,,0.126,,L,0.46,-0.35,3.626,,64.69,AHH,-1.63267,0.213352,0.00431903,0.959448 kka2_1:8_D157H,kka2_1:8_157,Kka2,kka2_1:8,P00552,0.959468,NO,157,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.993,-4.51,3.517,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.100394,0.0042313,0.959468 kka2_1:8_D157H,kka2_1:8_157,Kka2,kka2_1:8,P00552,0.959468,NO,157,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.993,-4.51,3.517,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.100394,0.0042313,0.959468 kka2_1:8_G151C,kka2_1:8_151,Kka2,kka2_1:8,P00552,0.959486,NO,151,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.873,-5.156,4.283,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.100394,0.00339918,0.959486 kka2_1:8_G151C,kka2_1:8_151,Kka2,kka2_1:8,P00552,0.959486,NO,151,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.873,-5.156,4.283,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.100394,0.00339918,0.959486 beta-lactamase_39_R202Y,beta-lactamase_39_202,TEM-1,beta-lactamase_39,P62593,0.959489,NO,202,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.292,-4.182,2.89,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.0495842,0.00321899,0.959489 beta-lactamase_39_K254P,beta-lactamase_39_254,TEM-1,beta-lactamase_39,P62593,0.959492,NO,254,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.0495842,0.00369,0.959492 beta-lactamase_625_D48Q,beta-lactamase_625_48,TEM-1,beta-lactamase_625,P62593,0.959495,NO,48,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.101,-3.681,2.58,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.213352,0.0027273,0.959495 beta-lactamase_0_E56I,beta-lactamase_0_56,TEM-1,beta-lactamase_0,P62593,0.959502,NO,56,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.043,-3.825,1.782,,0.198,E,B,1.04,0.31,1.491,,72.73,HAP,-1.94033,0.0500837,0.00238534,0.959502 Pab1_K131R,Pab1_131,Pab1,Pab1,P04147,0.959516,NO,131,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.083,-2.85,1.767,,0.462,E,B,1.82,0.57,,,,HBP,-1.12467,0.175299,0.000349395,0.959516 beta-lactamase_E108T,beta-lactamase_108,TEM-1,beta-lactamase,P62593,0.959523,NO,108,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.46,-3.526,2.066,5.52079,0.572,G,A,0.52,1.87,1.973,,72.73,PAB,-1.437,0.221079,0.00413372,0.959523 beta-lactamase_H151C,beta-lactamase_151,TEM-1,beta-lactamase,P62593,0.959523,NO,151,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-2.96,-5.124,2.164,5.47408,0.594,H,A,0.35,0.1,1.843,,77.62,HBP,-2.34767,0.221079,0.00216946,0.959523 beta-lactamase_K30S,beta-lactamase_30,TEM-1,beta-lactamase,P62593,0.959523,NO,30,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-2.307,-3.277,0.97,5.30605,0.142,H,A,1.82,-0.65,2.434,,93.01,HBH,-2.32833,0.221079,0.00448593,0.959523 beta-lactamase_K32E,beta-lactamase_32,TEM-1,beta-lactamase,P62593,0.959523,NO,32,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.984,-2.418,0.434,5.55842,0.563,H,A,1.82,0.34,1.754,,73.08,HBA,-2.04233,0.221079,0.00401283,0.959523 beta-lactamase_P253H,beta-lactamase_253,TEM-1,beta-lactamase,P62593,0.959523,NO,253,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-2.253,-3.37,1.117,5.24842,0.308,,B,0.73,-0.46,2.293,,73.08,BOP,-2.10633,0.221079,0.00786358,0.959523 beta-lactamase_V101C,beta-lactamase_101,TEM-1,beta-lactamase,P62593,0.959523,NO,101,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.295,-4.837,3.542,5.49045,0.342,,B,0.96,0,1.675,,73.08,HHA,-1.54367,0.221079,0.00374492,0.959523 beta-lactamase_V258I,beta-lactamase_258,TEM-1,beta-lactamase,P62593,0.959523,NO,258,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.975,-2.547,0.572,5.16083,,E,B,1.64,-1.02,2.124,,67.83,HHH,-1.67667,0.221079,0.007931,0.959523 beta-lactamase_2500_K53F,beta-lactamase_2500_53,TEM-1,beta-lactamase_2500,P62593,0.959525,NO,53,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-2.313,-4.249,1.936,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.361275,0.00383383,0.959525 beta-lactamase_39_E62N,beta-lactamase_39_62,TEM-1,beta-lactamase_39,P62593,0.959526,NO,62,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.193,-3.541,2.348,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.0495842,0.00264802,0.959526 beta-lactamase_2500_L146M,beta-lactamase_2500_146,TEM-1,beta-lactamase_2500,P62593,0.959546,NO,146,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.462,-4.183,2.721,,0.007,H,A,0.55,-0.56,1.578,,64.69,AHP,-1.656,0.361275,0.00474542,0.959546 beta-lactamase_2500_L79M,beta-lactamase_2500_79,TEM-1,beta-lactamase_2500,P62593,0.959548,NO,79,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.842,-2.761,1.919,,0.007,H,A,0.55,-0.16,0.823,,50.35,HHP,-1.44333,0.361275,0.000947397,0.959548 beta-lactamase_625_I171K,beta-lactamase_625_171,TEM-1,beta-lactamase_625,P62593,0.959558,NO,171,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-2.431,-2.528,0.097,,0.361,,B,0.48,0.53,3.869,,77.62,HHO,-1.55533,0.213352,0.00623355,0.959558 kka2_1:8_M116Y,kka2_1:8_116,Kka2,kka2_1:8,P00552,0.959561,NO,116,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-2.482,-2.927,0.445,,,H,A,1.59,-0.88,4.659,,71.59,HHH,-1.63867,0.100394,0.00745147,0.959561 kka2_1:8_M116Y,kka2_1:8_116,Kka2,kka2_1:8,P00552,0.959561,NO,116,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-2.482,-2.927,0.445,,,H,A,1.59,-0.88,4.659,,71.59,HHH,-1.63867,0.100394,0.00745147,0.959561 beta-lactamase_625_K213I,beta-lactamase_625_213,TEM-1,beta-lactamase_625,P62593,0.959567,NO,213,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.81,-4.142,2.332,,0.67,,A,2.34,0.29,3.924,,67.83,ABH,-1.57767,0.213352,0.00610411,0.959567 beta-lactamase_0_A200N,beta-lactamase_0_200,TEM-1,beta-lactamase_0,P62593,0.959576,NO,200,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.878,-3.758,1.88,,0.757,H,A,0.46,-0.19,16.368,16.368,77.62,HHP,-2.001,0.0500837,0.0060056,0.959576 beta-lactamase_625_L197V,beta-lactamase_625_197,TEM-1,beta-lactamase_625,P62593,0.959595,NO,197,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.853,-2.903,2.05,,0.007,S,B,0.55,0.33,1.756,,60.14,HHP,-1.833,0.213352,0.00144602,0.959595 gb1_K239H,gb1_239,gb1,gb1,P06654,0.959607,NO,239,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-3.043,-4.016,0.973,,,,,,,1.326,,45.54,HBO,-2.31467,0.177985,0.00207004,0.959607 beta-lactamase_39_D161K,beta-lactamase_39_161,TEM-1,beta-lactamase_39,P62593,0.959615,NO,161,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.891,-3.426,2.535,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.0495842,0.000897697,0.959615 beta-lactamase_A211T,beta-lactamase_211,TEM-1,beta-lactamase,P62593,0.959644,NO,211,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.896,-2.901,1.005,5.54662,0.369,T,A,0.52,-0.69,2.061,,77.62,AHA,-1.94633,0.221079,0.00648183,0.959644 beta-lactamase_156_Y95T,beta-lactamase_156_95,TEM-1,beta-lactamase_156,P62593,0.959654,NO,95,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-1.715,-3.697,1.982,,0.122,,b,0.21,-0.37,2.341,,77.62,BHP,-2.16167,0.111618,0.00479449,0.959654 beta-lactamase_39_V260F,beta-lactamase_39_260,TEM-1,beta-lactamase_39,P62593,0.95966,NO,260,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.0495842,0.00471757,0.95966 Ubiquitin_A46C,Ubiquitin_46,Uba1,Ubiquitin,P0CG48,0.959677,NO,46,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.77,-3.288,1.518,5.38761,0.398,T,L,2.34,-0.8,6.506,,51.09,HHO,-1.505,0.205827,0.000581142,0.959677 Ubiquitin_A46G,Ubiquitin_46,Uba1,Ubiquitin,P0CG48,0.959677,NO,46,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.77,-2.105,0.335,5.38761,0.398,T,L,2.34,-0.8,6.506,,51.09,HHO,-1.505,0.205827,0.000581142,0.959677 Ubiquitin_D21Y,Ubiquitin_21,Uba1,Ubiquitin,P0CG48,0.959677,NO,21,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.193,-2.848,1.655,4.96432,0.165,,B,0.23,-0.53,1.013,,71.82,PAP,-1.35867,0.205827,0.000465257,0.959677 Ubiquitin_D24A,Ubiquitin_24,Uba1,Ubiquitin,P0CG48,0.959677,NO,24,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,,,,,,,,,,,,,HAP,,0.205827,0.0066591,0.959677 Ubiquitin_D24G,Ubiquitin_24,Uba1,Ubiquitin,P0CG48,0.959677,NO,24,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,,,,,,,,,,,,,HAP,,0.205827,0.0066591,0.959677 Ubiquitin_D39M,Ubiquitin_39,Uba1,Ubiquitin,P0CG48,0.959677,NO,39,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.792,-4.814,3.022,5.1607,0.433,G,A,,0.55,,,,OAP,-1.754,0.205827,0.00071409,0.959677 Ubiquitin_E51H,Ubiquitin_51,Uba1,Ubiquitin,P0CG48,0.959677,NO,51,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.534,-4.512,2.978,5.36711,0.545,,B,,0.72,,,,HAA,-1.357,0.205827,0.000868134,0.959677 Ubiquitin_E51T,Ubiquitin_51,Uba1,Ubiquitin,P0CG48,0.959677,NO,51,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.534,-3.497,1.963,5.36711,0.545,,B,,0.72,,,,HAA,-1.357,0.205827,0.000868134,0.959677 Ubiquitin_F45N,Ubiquitin_45,Uba1,Ubiquitin,P0CG48,0.959677,NO,45,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.322,-4.077,2.755,4.80693,0.26,E,B,1.62,-0.99,1.531,,53.87,HHH,-1.55267,0.205827,0.000470401,0.959677 Ubiquitin_I23A,Ubiquitin_23,Uba1,Ubiquitin,P0CG48,0.959677,NO,23,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.325,-3.099,1.774,4.67534,,H,A,0.01,-0.93,0.515,,52.12,PHA,-1.54033,0.205827,0.000621252,0.959677 Ubiquitin_K33C,Ubiquitin_33,Uba1,Ubiquitin,P0CG48,0.959677,NO,33,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.283,-4.989,3.706,5.08526,0.64,H,A,1.82,1.2,1.509,,51.09,ABA,-1.34267,0.205827,0.000712743,0.959677 Ubiquitin_K33H,Ubiquitin_33,Uba1,Ubiquitin,P0CG48,0.959677,NO,33,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.283,-4.596,3.313,5.08526,0.64,H,A,1.82,1.2,1.509,,51.09,ABA,-1.34267,0.205827,0.000712743,0.959677 Ubiquitin_K33S,Ubiquitin_33,Uba1,Ubiquitin,P0CG48,0.959677,NO,33,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.283,-3.371,2.088,5.08526,0.64,H,A,1.82,1.2,1.509,,51.09,ABA,-1.34267,0.205827,0.000712743,0.959677 Ubiquitin_K48K,Ubiquitin_48,Uba1,Ubiquitin,P0CG48,0.959677,NO,48,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.436,-1.436,0,5.03072,0.132,E,B,2.92,-0.28,1.539,,53.87,OBP,-1.6,0.205827,0.000394633,0.959677 Ubiquitin_K63C,Ubiquitin_63,Uba1,Ubiquitin,P0CG48,0.959677,NO,63,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.635,-5.166,3.531,5.08297,0.721,T,B,,0.59,,,,PBA,-1.74467,0.205827,0.000607964,0.959677 Ubiquitin_K63P,Ubiquitin_63,Uba1,Ubiquitin,P0CG48,0.959677,NO,63,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.635,-3.87,2.235,5.08297,0.721,T,B,,0.59,,,,PBA,-1.74467,0.205827,0.000607964,0.959677 Ubiquitin_K63Q,Ubiquitin_63,Uba1,Ubiquitin,P0CG48,0.959677,NO,63,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.635,-2.897,1.262,5.08297,0.721,T,B,,0.59,,,,PBA,-1.74467,0.205827,0.000607964,0.959677 Ubiquitin_L50V,Ubiquitin_50,Uba1,Ubiquitin,P0CG48,0.959677,NO,50,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.107,-3.011,1.904,5.19399,0.029,,B,,-0.92,,,,PHA,-1.52733,0.205827,0.000734242,0.959677 Ubiquitin_N60K,Ubiquitin_60,Uba1,Ubiquitin,P0CG48,0.959677,NO,60,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-1.775,-2.618,0.843,5.00332,0.775,T,L,,0.33,,,,HPH,-1.532,0.205827,0.000814061,0.959677 Ubiquitin_Q2M,Ubiquitin_2,Uba1,Ubiquitin,P0CG48,0.959677,NO,2,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-1.7,-4.345,2.645,4.89203,0.475,E,B,,0.1,,,,OPH,-1.551,0.205827,0.00085006,0.959677 Ubiquitin_Q40A,Ubiquitin_40,Uba1,Ubiquitin,P0CG48,0.959677,NO,40,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-1.752,-2.631,0.879,4.7807,0.387,G,A,,0.03,,,,APP,-1.62433,0.205827,0.000619089,0.959677 Ubiquitin_Q40N,Ubiquitin_40,Uba1,Ubiquitin,P0CG48,0.959677,NO,40,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-1.752,-3.657,1.905,4.7807,0.387,G,A,,0.03,,,,APP,-1.62433,0.205827,0.000619089,0.959677 Ubiquitin_Q41M,Ubiquitin_41,Uba1,Ubiquitin,P0CG48,0.959677,NO,41,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-1.329,-4.323,2.994,4.9201,0.017,E,B,0.12,-0.98,0.812,,30.07,PPB,-1.55067,0.205827,0.000521668,0.959677 Ubiquitin_Q49G,Ubiquitin_49,Uba1,Ubiquitin,P0CG48,0.959677,NO,49,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-1.941,-3.56,1.619,5.05026,0.403,E,B,,-0.59,,,,BPH,-1.49467,0.205827,0.000613067,0.959677 Ubiquitin_S20P,Ubiquitin_20,Uba1,Ubiquitin,P0CG48,0.959677,NO,20,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.539,-2.788,1.249,5.15339,0.672,T,A,,-0.6,,,,OPA,-1.69467,0.205827,0.000670478,0.959677 Ubiquitin_S65V,Ubiquitin_65,Uba1,Ubiquitin,P0CG48,0.959677,NO,65,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.535,-3.494,1.959,4.99442,0.168,,b,0.25,-0.68,16.756,16.756,33.87,APP,-1.626,0.205827,0.000546776,0.959677 Ubiquitin_S65Y,Ubiquitin_65,Uba1,Ubiquitin,P0CG48,0.959677,NO,65,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.535,-3.07,1.535,4.99442,0.168,,b,0.25,-0.68,16.756,16.756,33.87,APP,-1.626,0.205827,0.000546776,0.959677 Ubiquitin_T22D,Ubiquitin_22,Uba1,Ubiquitin,P0CG48,0.959677,NO,22,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.344,-3.473,2.129,4.54389,0.237,B,B,,-0.75,,,,APH,-1.28733,0.205827,0.000535592,0.959677 Ubiquitin_T22K,Ubiquitin_22,Uba1,Ubiquitin,P0CG48,0.959677,NO,22,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.344,-3.383,2.039,4.54389,0.237,B,B,,-0.75,,,,APH,-1.28733,0.205827,0.000535592,0.959677 Ubiquitin_T22N,Ubiquitin_22,Uba1,Ubiquitin,P0CG48,0.959677,NO,22,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.344,-2.589,1.245,4.54389,0.237,B,B,,-0.75,,,,APH,-1.28733,0.205827,0.000535592,0.959677 Ubiquitin_T9Q,Ubiquitin_9,Uba1,Ubiquitin,P0CG48,0.959677,NO,9,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.409,-2.853,1.444,5.24336,0.777,T,A,2.12,-0.12,2.705,,29.93,HPO,-1.50933,0.205827,0.000630716,0.959677 Ubiquitin_T9S,Ubiquitin_9,Uba1,Ubiquitin,P0CG48,0.959677,NO,9,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.409,-2.288,0.879,5.24336,0.777,T,A,2.12,-0.12,2.705,,29.93,HPO,-1.50933,0.205827,0.000630716,0.959677 Ubiquitin_V26M,Ubiquitin_26,Uba1,Ubiquitin,P0CG48,0.959677,NO,26,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.321,-4.105,2.784,4.78447,,H,A,,-0.97,,,,PHB,-1.445,0.205827,0.000980269,0.959677 Ubiquitin_V5A,Ubiquitin_5,Uba1,Ubiquitin,P0CG48,0.959677,NO,5,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.576,-2.17,0.594,4.75677,,E,B,,-0.82,,,,HHB,-1.401,0.205827,0.000796998,0.959677 beta-lactamase_2500_E169V,beta-lactamase_2500_169,TEM-1,beta-lactamase_2500,P62593,0.959681,NO,169,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.23,-3.538,2.308,,0.337,,A,1.04,1,1.806,,73.08,PAH,-1.16533,0.361275,0.00400994,0.959681 beta-lactamase_39_E210I,beta-lactamase_39_210,TEM-1,beta-lactamase_39,P62593,0.959681,NO,210,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.319,-2.456,0.137,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.0495842,0.00663582,0.959681 beta-lactamase_E237I,beta-lactamase_237,TEM-1,beta-lactamase,P62593,0.959683,NO,237,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.058,-4.083,2.025,5.42877,0.583,S,B,1.62,1.2,2.144,,77.62,OAB,-1.61467,0.221079,0.0048626,0.959683 kka2_1:2_A137N,kka2_1:2_137,Kka2,kka2_1:2,P00552,0.959697,NO,137,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.156,-4.15,1.994,,0.029,H,A,0.46,0.34,1.323,,63.26,PHB,-2.559,0.295029,0.00515054,0.959697 beta-lactamase_0_P25E,beta-lactamase_0_25,TEM-1,beta-lactamase_0,P62593,0.959709,NO,25,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.526,-2.543,1.017,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.0500837,0.00347571,0.959709 Pab1_A182C,Pab1_182,Pab1,Pab1,P04147,0.959709,NO,182,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.013,-4.229,3.216,,,H,A,0.17,0.79,,,,AHH,-1.36067,0.175299,0.000289034,0.959709 PSD95pdz3_G364I,PSD95pdz3_364,PSD95pdz3,PSD95pdz3,P31016,0.959746,NO,364,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.008,-3.917,2.909,5.53299,,,,,21.28,,,,POH,-1.33667,0.0758425,0.00050942,0.959746 beta-lactamase_625_T139W,beta-lactamase_625_139,TEM-1,beta-lactamase_625,P62593,0.95975,NO,139,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.901,-5.432,3.531,,0.216,H,A,0.22,0.39,2.256,,77.62,PPH,-2.04667,0.213352,0.00441837,0.95975 beta-lactamase_H94G,beta-lactamase_94,TEM-1,beta-lactamase,P62593,0.959761,NO,94,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-2.5,-3.593,1.093,6.1507,0.776,,B,0.63,1.24,1.176,,77.62,HBH,-1.872,0.221079,0.00389226,0.959761 beta-lactamase_2500_E26T,beta-lactamase_2500_26,TEM-1,beta-lactamase_2500,P62593,0.959777,NO,26,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.454,-2.753,0.299,,0.54,H,A,1.04,0.98,0.49,,93.01,OAP,-1.96167,0.361275,0.00297948,0.959777 beta-lactamase_625_P217M,beta-lactamase_625_217,TEM-1,beta-lactamase_625,P62593,0.959779,NO,217,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-2.062,-4.835,2.773,,0.496,I,A,0.52,-0.33,1.087,,74.48,OOH,-1.64333,0.213352,0.00463211,0.959779 beta-lactamase_0_N152A,beta-lactamase_0_152,TEM-1,beta-lactamase_0,P62593,0.959792,NO,152,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-2.757,-2.374,-0.383,,0.863,H,A,0.61,0.92,2.151,,77.62,BPH,-2.97,0.0500837,0.00471429,0.959792 beta-lactamase_156_L136C,beta-lactamase_156_136,TEM-1,beta-lactamase_156,P62593,0.959806,NO,136,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.232,-4.751,3.519,,,H,A,0.55,-0.34,1.04,,48.95,HHH,-1.088,0.111618,0.00442304,0.959806 beta-lactamase_P253I,beta-lactamase_253,TEM-1,beta-lactamase,P62593,0.959808,NO,253,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-2.253,-4.101,1.848,5.24842,0.308,,B,0.73,-0.46,2.293,,73.08,BOP,-2.10633,0.221079,0.00786358,0.959808 kka2_1:2_D227S,kka2_1:2_227,Kka2,kka2_1:2,P00552,0.959824,NO,227,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.758,-1.053,-0.705,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.295029,0.00745029,0.959824 kka2_1:8_R202L,kka2_1:8_202,Kka2,kka2_1:8,P00552,0.959839,NO,202,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.761,-3.611,1.85,,0.607,E,B,1.2,0.48,1.409,,52.27,OBH,-1.41067,0.100394,0.00696498,0.959839 kka2_1:8_R202L,kka2_1:8_202,Kka2,kka2_1:8,P00552,0.959839,NO,202,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.761,-3.611,1.85,,0.607,E,B,1.2,0.48,1.409,,52.27,OBH,-1.41067,0.100394,0.00696498,0.959839 Pab1_D136I,Pab1_136,Pab1,Pab1,P04147,0.959842,NO,136,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.602,-3.418,1.816,,,,,,,,,,OAH,-1.42367,0.175299,0.00227029,0.959842 beta-lactamase_2500_S221I,beta-lactamase_2500_221,TEM-1,beta-lactamase_2500,P62593,0.959846,NO,221,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.754,-3.812,2.058,,0.624,H,A,0.27,-0.2,1.971,,74.48,BPH,-1.59967,0.361275,0.0046094,0.959846 PSD95pdz3_N363R,PSD95pdz3_363,PSD95pdz3,PSD95pdz3,P31016,0.959846,NO,363,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-1.41,-3.165,1.755,5.23349,,,,,20.7037,,,,HPO,-1.29433,0.0758425,0.000524014,0.959846 kka2_1:4_V97C,kka2_1:4_97,Kka2,kka2_1:4,P00552,0.959854,NO,97,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.453,-4.797,3.344,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.168804,0.00737869,0.959854 beta-lactamase_39_K254C,beta-lactamase_39_254,TEM-1,beta-lactamase_39,P62593,0.959864,NO,254,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.0495842,0.00369,0.959864 beta-lactamase_39_K254S,beta-lactamase_39_254,TEM-1,beta-lactamase_39,P62593,0.959868,NO,254,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-2.126,-3.446,1.32,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.0495842,0.00369,0.959868 beta-lactamase_2500_H24Q,beta-lactamase_2500_24,TEM-1,beta-lactamase_2500,P62593,0.959878,NO,24,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-2.481,-2.604,0.123,,,,,,,0.467,,93.01,OBO,-2.0035,0.361275,0.00238894,0.959878 beta-lactamase_625_R63C,beta-lactamase_625_63,TEM-1,beta-lactamase_625,P62593,0.959879,NO,63,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-0.943,-5.05,4.107,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.213352,0.00126938,0.959879 beta-lactamase_0_K213G,beta-lactamase_0_213,TEM-1,beta-lactamase_0,P62593,0.959884,NO,213,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.81,-2.317,0.507,,0.67,,A,2.34,0.29,3.015,,67.83,ABH,-1.57767,0.0500837,0.00610411,0.959884 beta-lactamase_625_V214P,beta-lactamase_625_214,TEM-1,beta-lactamase_625,P62593,0.959891,NO,214,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.299,-3.919,2.62,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.213352,0.00628442,0.959891 beta-lactamase_0_G194M,beta-lactamase_0_194,TEM-1,beta-lactamase_0,P62593,0.959904,NO,194,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.396,-4.893,3.497,,0.276,S,b,0.29,0.36,3.017,,67.83,POA,-1.832,0.0500837,0.00392163,0.959904 beta-lactamase_0_L284S,beta-lactamase_0_284,TEM-1,beta-lactamase_0,P62593,0.95991,NO,284,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.981,,,,0.848,H,A,2.89,0.67,4.544,,77.62,PHH,-1.82133,0.0500837,0.0686156,0.95991 beta-lactamase_39_D207K,beta-lactamase_39_207,TEM-1,beta-lactamase_39,P62593,0.959936,NO,207,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.064,-2.897,0.833,,0.409,H,A,0.75,0.12,14.511,14.511,77.62,HAH,-1.77033,0.0495842,0.00592942,0.959936 beta-lactamase_39_T139G,beta-lactamase_39_139,TEM-1,beta-lactamase_39,P62593,0.959945,NO,139,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.901,-3.413,1.512,,0.216,H,A,0.22,0.39,0.421,,77.62,PPH,-2.04667,0.0495842,0.00441837,0.959945 kka2_1:4_K175S,kka2_1:4_175,Kka2,kka2_1:4,P00552,0.959951,NO,175,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-2.897,-3.083,0.186,,0.579,H,A,1.3,0.51,15.629,15.629,71.59,HBH,-1.82333,0.168804,0.00693093,0.959951 PSD95pdz3_E331T,PSD95pdz3_331,PSD95pdz3,PSD95pdz3,P31016,0.959968,NO,331,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.404,-3.103,1.699,5.86289,,,,,51.8889,,,,OAA,-1.22533,0.0758425,0.000950134,0.959968 beta-lactamase_2500_G90I,beta-lactamase_2500_90,TEM-1,beta-lactamase_2500,P62593,0.95998,NO,90,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-2.091,-4.052,1.961,,0.598,T,A,0.29,0.32,1.2,,77.62,HOB,-1.52633,0.361275,0.00490273,0.95998 beta-lactamase_T139N,beta-lactamase_139,TEM-1,beta-lactamase,P62593,0.959989,NO,139,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.901,-3.686,1.785,5.69095,0.216,H,A,0.3,0.39,2.256,,77.62,PPH,-2.04667,0.221079,0.00441837,0.959989 beta-lactamase_39_M184G,beta-lactamase_39_184,TEM-1,beta-lactamase_39,P62593,0.95999,NO,184,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.593,-3.601,2.008,,,H,A,0.55,-0.87,2.893,,62.94,HHH,-1.41,0.0495842,0.00356019,0.95999 beta-lactamase_625_R189N,beta-lactamase_625_189,TEM-1,beta-lactamase_625,P62593,0.960001,NO,189,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.844,-3.633,1.789,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.213352,0.0050699,0.960001 gb1_L231C,gb1_231,gb1,gb1,P06654,0.96002,NO,231,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.603,-4.554,2.951,,,,,,,0.219,,11.83,BHH,-1.82633,0.177985,0.00322797,0.96002 Pab1_N139T,Pab1_139,Pab1,Pab1,P04147,0.960045,NO,139,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-1.079,-3.014,1.935,,0.062,H,A,,-0.73,,,,APB,-1.09667,0.175299,0.000339145,0.960045 kka2_1:4_Y22H,kka2_1:4_22,Kka2,kka2_1:4,P00552,0.960054,NO,22,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-1.583,-2.746,1.163,,0.122,.,B,0.21,-0.8,1.838,,65.53,OHA,-1.80333,0.168804,0.00598977,0.960054 beta-lactamase_0_P250H,beta-lactamase_0_250,TEM-1,beta-lactamase_0,P62593,0.960073,NO,250,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.0500837,0.00550899,0.960073 kka2_1:8_L212F,kka2_1:8_212,Kka2,kka2_1:8,P00552,0.960081,NO,212,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.904,-3.768,2.864,,,,B,1.59,-0.78,1.708,,42.42,BHO,-0.799667,0.100394,0.0031426,0.960081 kka2_1:8_L212F,kka2_1:8_212,Kka2,kka2_1:8,P00552,0.960081,NO,212,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.904,-3.768,2.864,,,,B,1.59,-0.78,1.708,,42.42,BHO,-0.799667,0.100394,0.0031426,0.960081 beta-lactamase_0_C75W,beta-lactamase_0_75,TEM-1,beta-lactamase_0,P62593,0.960086,NO,75,C,W,CW,Special,Hydrophobic,5.07,5.89,0.82,215,121,204,83,108.5,227.8,119.3,-1.245,-5.246,4.001,,,H,A,0.46,-0.87,2.256,,50,HOO,-1.24333,0.0500837,0.0034616,0.960086 beta-lactamase_I283L,beta-lactamase_283,TEM-1,beta-lactamase,P62593,0.960086,NO,283,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.638,-2.746,1.108,5.4178,0.165,H,A,1.23,0.04,1.576,,69.23,HHB,-1.735,0.221079,0.0429138,0.960086 kka2_1:8_P179A,kka2_1:8_179,Kka2,kka2_1:8,P00552,0.960099,NO,179,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.974,-2.519,1.545,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.100394,0.00298346,0.960099 kka2_1:8_P179A,kka2_1:8_179,Kka2,kka2_1:8,P00552,0.960099,NO,179,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.974,-2.519,1.545,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.100394,0.00298346,0.960099 beta-lactamase_39_G142T,beta-lactamase_39_142,TEM-1,beta-lactamase_39,P62593,0.960109,NO,142,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.707,-3.568,2.861,,0.034,,p,0.29,-0.64,1.947,,64.69,OOO,-0.834,0.0495842,0.00060149,0.960109 beta-lactamase_2500_L73P,beta-lactamase_2500_73,TEM-1,beta-lactamase_2500,P62593,0.960111,NO,73,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.507,-2.751,1.244,,,H,A,0.55,-0.64,2.178,,67.83,HHH,-1.487,0.361275,0.00488983,0.960111 beta-lactamase_156_Q203I,beta-lactamase_156_203,TEM-1,beta-lactamase_156,P62593,0.960123,NO,203,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.168,-3.973,1.805,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.111618,0.00631514,0.960123 beta-lactamase_39_T147C,beta-lactamase_39_147,TEM-1,beta-lactamase_39,P62593,0.960129,NO,147,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.149,-4.804,3.655,,0.281,H,A,0.22,-0.68,13.843,13.843,64.34,HPH,-1.456,0.0495842,0.00226017,0.960129 beta-lactamase_39_V101R,beta-lactamase_39_101,TEM-1,beta-lactamase_39,P62593,0.96013,NO,101,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.295,-4.134,2.839,,0.342,,B,0.44,0,2.96,,73.08,HHA,-1.54367,0.0495842,0.00374492,0.96013 beta-lactamase_39_V42L,beta-lactamase_39_42,TEM-1,beta-lactamase_39,P62593,0.960142,NO,42,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.564,-1.709,0.145,,0.017,E,B,0.44,-0.51,1.86,,63.99,BHO,-1.042,0.0495842,0.00404515,0.960142 kka2_1:8_A35E,kka2_1:8_35,Kka2,kka2_1:8,P00552,0.960155,NO,35,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.127,-2.492,0.365,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.100394,0.00630016,0.960155 kka2_1:8_A35E,kka2_1:8_35,Kka2,kka2_1:8,P00552,0.960155,NO,35,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.127,-2.492,0.365,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.100394,0.00630016,0.960155 beta-lactamase_S233G,beta-lactamase_233,TEM-1,beta-lactamase,P62593,0.960175,NO,233,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.886,-3.274,1.388,4.98121,0.016,E,B,0.48,-1.01,5.361,,77.62,BPO,-1.17267,0.221079,0.00311415,0.960175 PSD95pdz3_I388A,PSD95pdz3_388,PSD95pdz3,PSD95pdz3,P31016,0.960197,NO,388,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.63,-2.759,1.129,5.17282,,,,,16.0025,,,,PHH,-1.54967,0.0758425,0.000151216,0.960197 beta-lactamase_156_D161M,beta-lactamase_156_161,TEM-1,beta-lactamase_156,P62593,0.960205,NO,161,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.891,-4.899,4.008,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.111618,0.000897697,0.960205 beta-lactamase_D36H,beta-lactamase_36,TEM-1,beta-lactamase,P62593,0.960205,NO,36,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.732,-3.09,0.358,5.39764,0.555,H,A,0.11,1.17,13.689,13.689,77.62,AAP,-1.91167,0.221079,0.00476483,0.960205 E1_Ubiquitin_G47N,E1_Ubiquitin_47,Uba1,E1_Ubiquitin,P0CG63,0.960212,NO,47,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.999,-3.318,2.319,,0.057,T,l,,-1.21,,,,HOB,-1.195,0.18783,0.00142261,0.960212 E1_Ubiquitin_K48Q,E1_Ubiquitin_48,Uba1,E1_Ubiquitin,P0CG63,0.960212,NO,48,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.219,-3.26,2.041,,0.132,E,B,,-0.28,,,,OBO,-1.109,0.18783,0.00100363,0.960212 PSD95pdz3_G319D,PSD95pdz3_319,PSD95pdz3,PSD95pdz3,P31016,0.960217,NO,319,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.008,-3.15,2.142,4.95387,,,,,18.8725,,,,BOP,-1.36967,0.0758425,0.00109317,0.960217 beta-lactamase_156_A148Y,beta-lactamase_156_148,TEM-1,beta-lactamase_156,P62593,0.960221,NO,148,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.757,-4.336,2.579,,0.379,H,A,0.46,-0.55,3.551,,72.73,PHH,-1.40167,0.111618,0.00547053,0.960221 beta-lactamase_2500_V157C,beta-lactamase_2500_157,TEM-1,beta-lactamase_2500,P62593,0.960243,NO,157,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.751,-4.91,3.159,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.361275,0.00506849,0.960243 beta-lactamase_T198C,beta-lactamase_198,TEM-1,beta-lactamase,P62593,0.960247,NO,198,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.168,-4.902,2.734,4.9209,0.489,,B,0.69,-0.13,0.37,,73.78,HPH,-1.98767,0.221079,0.004311,0.960247 beta-lactamase_39_D177S,beta-lactamase_39_177,TEM-1,beta-lactamase_39,P62593,0.960277,NO,177,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.967,-3.186,2.219,,0.006,T,L,0.75,-1.02,3.536,,64.69,BAP,-0.873667,0.0495842,0.000864022,0.960277 PSD95pdz3_S361A,PSD95pdz3_361,PSD95pdz3,PSD95pdz3,P31016,0.960278,NO,361,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.519,-2.309,0.79,4.8722,,,,,16.4533,,,,HPH,-1.47167,0.0758425,0.00055296,0.960278 kka2_1:8_L259M,kka2_1:8_259,Kka2,kka2_1:8,P00552,0.960285,NO,259,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.088,-2.71,1.622,,0.036,H,A,1.59,-0.15,1.83,,48.48,BHH,-1.15167,0.100394,0.0206964,0.960285 kka2_1:8_L259M,kka2_1:8_259,Kka2,kka2_1:8,P00552,0.960285,NO,259,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.088,-2.71,1.622,,0.036,H,A,1.59,-0.15,1.83,,48.48,BHH,-1.15167,0.100394,0.0206964,0.960285 beta-lactamase_0_P60N,beta-lactamase_0_60,TEM-1,beta-lactamase_0,P62593,0.960312,NO,60,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-2.469,-3.804,1.335,,0.256,T,A,0.52,-0.56,3.653,,77.62,BOA,-1.97633,0.0500837,0.00521318,0.960312 beta-lactamase_2500_G85A,beta-lactamase_2500_85,TEM-1,beta-lactamase_2500,P62593,0.960324,NO,85,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.011,-3.043,2.032,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.361275,0.00252173,0.960324 beta-lactamase_2500_A246C,beta-lactamase_2500_246,TEM-1,beta-lactamase_2500,P62593,0.960331,NO,246,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.121,-3.242,1.121,,0.01,E,B,0.46,-1.01,0.753,,73.78,HHH,-1.55633,0.361275,0.00569458,0.960331 beta-lactamase_39_D271M,beta-lactamase_39_271,TEM-1,beta-lactamase_39,P62593,0.960336,NO,271,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.0495842,0.00752082,0.960336 PSD95pdz3_A382H,PSD95pdz3_382,PSD95pdz3,PSD95pdz3,P31016,0.96034,NO,382,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.307,-4.362,3.055,5.30282,,,,,22.472,,,,PHO,-1.24167,0.0758425,0.000249256,0.96034 kka2_1:4_F171Y,kka2_1:4_171,Kka2,kka2_1:4,P00552,0.960344,NO,171,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.326,-2.217,0.891,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.168804,0.00821426,0.960344 kka2_1:1_V242N,kka2_1:1_242,Kka2,kka2_1:1,P00552,0.960345,NO,242,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-2.687,-3.122,0.435,,0.75,H,A,0.44,-0.37,4.987,,71.59,HHH,-2.16533,0.520039,0.0102575,0.960345 kka2_1:2_A247V,kka2_1:2_247,Kka2,kka2_1:2,P00552,0.960345,NO,247,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.459,-2.971,0.512,,1.01,S,A,0.46,0.65,0.828,,92.05,HHH,-2.197,0.295029,0.0102428,0.960345 PSD95pdz3_V386Q,PSD95pdz3_386,PSD95pdz3,PSD95pdz3,P31016,0.960347,NO,386,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.465,-3.806,2.341,5.18836,,,,,17.5429,,,,PHP,-1.463,0.0758425,0.000184509,0.960347 beta-lactamase_2500_Q203A,beta-lactamase_2500_203,TEM-1,beta-lactamase_2500,P62593,0.960382,NO,203,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.168,-2.117,-0.051,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.361275,0.00631514,0.960382 beta-lactamase_39_M115S,beta-lactamase_39_115,TEM-1,beta-lactamase_39,P62593,0.960385,NO,115,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.389,-3.501,2.112,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.0495842,0.0034337,0.960385 beta-lactamase_A276Y,beta-lactamase_276,TEM-1,beta-lactamase,P62593,0.960412,NO,276,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.144,-4.213,3.069,5.1387,0.117,H,A,0.52,-0.84,1.283,,44.06,HHA,-1.47,0.221079,0.0191712,0.960412 beta-lactamase_A280Y,beta-lactamase_280,TEM-1,beta-lactamase,P62593,0.960412,NO,280,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.708,-4.214,2.506,4.74932,0.379,H,A,0.52,-0.72,1.785,,68.18,OHP,-1.66433,0.221079,0.0530888,0.960412 beta-lactamase_A77F,beta-lactamase_77,TEM-1,beta-lactamase,P62593,0.960412,NO,77,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.234,-4.125,2.891,4.75777,0.039,H,A,0.52,-0.56,1.708,,64.34,OHH,-1.294,0.221079,0.00282362,0.960412 beta-lactamase_E61F,beta-lactamase_61,TEM-1,beta-lactamase,P62593,0.960412,NO,61,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.115,-4.422,2.307,6.29701,0.775,T,a,0.52,1.29,1.975,,77.62,OAA,-1.92567,0.221079,0.00440955,0.960412 beta-lactamase_R271V,beta-lactamase_271,TEM-1,beta-lactamase,P62593,0.960412,NO,271,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.249,-3.515,2.266,5.24516,0.085,H,A,1.67,-0.05,0.474,,63.99,ABP,-1.36633,0.221079,0.00752082,0.960412 beta-lactamase_R273D,beta-lactamase_273,TEM-1,beta-lactamase,P62593,0.960412,NO,273,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.314,-3.543,1.229,,0.564,H,A,1.2,1.57,,,73.78,ABP,-1.841,0.221079,0.0077952,0.960412 kka2_1:2_D134M,kka2_1:2_134,Kka2,kka2_1:2,P00552,0.960442,NO,134,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.969,-4.823,3.854,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.295029,0.00270812,0.960442 PSD95pdz3_D332Q,PSD95pdz3_332,PSD95pdz3,PSD95pdz3,P31016,0.960458,NO,332,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.264,-3.356,2.092,6.09878,,,,,48.762,,,,AAO,-1.22533,0.0758425,0.000937818,0.960458 beta-lactamase_2500_A183I,beta-lactamase_2500_183,TEM-1,beta-lactamase_2500,P62593,0.960473,NO,183,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.231,-2.835,1.604,,0.155,H,A,0.46,-0.91,12.189,,77.62,HHH,-1.53367,0.361275,0.00296631,0.960473 beta-lactamase_39_L218D,beta-lactamase_39_218,TEM-1,beta-lactamase_39,P62593,0.960481,NO,218,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.391,-3.905,2.514,,,I,b,0.55,-0.53,2.038,,74.48,OHH,-1.58867,0.0495842,0.00618274,0.960481 beta-lactamase_156_D48L,beta-lactamase_156_48,TEM-1,beta-lactamase_156,P62593,0.96049,NO,48,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.101,-3.744,2.643,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.111618,0.0027273,0.96049 beta-lactamase_39_L120F,beta-lactamase_39_120,TEM-1,beta-lactamase_39,P62593,0.960517,NO,120,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.044,-2.785,1.741,,,H,A,0.55,-1.13,22.254,22.254,64.69,AHO,-1.13633,0.0495842,0.00143563,0.960517 beta-lactamase_39_E210K,beta-lactamase_39_210,TEM-1,beta-lactamase_39,P62593,0.960519,NO,210,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.319,-2.868,0.549,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.0495842,0.00663582,0.960519 Pab1_N139D,Pab1_139,Pab1,Pab1,P04147,0.960524,NO,139,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-1.079,-2.836,1.757,,0.062,H,A,,-0.73,,,,APB,-1.09667,0.175299,0.000339145,0.960524 beta-lactamase_0_A148Q,beta-lactamase_0_148,TEM-1,beta-lactamase_0,P62593,0.960532,NO,148,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.757,-3.083,1.326,,0.379,H,A,0.46,-0.55,19.42,19.42,72.73,PHH,-1.40167,0.0500837,0.00547053,0.960532 beta-lactamase_156_K254Q,beta-lactamase_156_254,TEM-1,beta-lactamase_156,P62593,0.960549,NO,254,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.111618,0.00369,0.960549 beta-lactamase_0_Q204T,beta-lactamase_0_204,TEM-1,beta-lactamase_0,P62593,0.960579,NO,204,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-1.382,-3.549,2.167,,0.204,H,A,0.64,0.09,2.646,,66.08,PPH,-1.49067,0.0500837,0.00364106,0.960579 beta-lactamase_S254Y,beta-lactamase_254,TEM-1,beta-lactamase,P62593,0.960591,NO,254,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.126,-4.394,2.268,5.49575,0.312,,a,0.25,-0.48,24.91,24.91,69.58,OPB,-2.215,0.221079,0.00369,0.960591 Pab1_I130V,Pab1_130,Pab1,Pab1,P04147,0.960618,NO,130,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.212,-2.221,1.009,,,E,B,1.23,0.01,,,,HHB,-1.188,0.175299,0.000351112,0.960618 beta-lactamase_0_K213W,beta-lactamase_0_213,TEM-1,beta-lactamase_0,P62593,0.960622,NO,213,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.81,-5.386,3.576,,0.67,,A,2.34,0.29,3.015,,67.83,ABH,-1.57767,0.0500837,0.00610411,0.960622 gb1_D266L,gb1_266,gb1,gb1,P06654,0.960637,NO,266,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.261,-3.405,2.144,,,,,,,0.638,,45.54,HAO,-1.59333,0.177985,0.00394694,0.960637 beta-lactamase_R238L,beta-lactamase_238,TEM-1,beta-lactamase,P62593,0.960667,NO,238,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.002,-3.515,1.513,5.87663,0.564,T,L,0.45,1.09,4.195,,72.73,ABO,-1.62633,0.221079,0.00743256,0.960667 beta-lactamase_2500_P250R,beta-lactamase_2500_250,TEM-1,beta-lactamase_2500,P62593,0.960672,NO,250,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.361275,0.00550899,0.960672 beta-lactamase_F70A,beta-lactamase_70,TEM-1,beta-lactamase,P62593,0.960673,NO,70,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.169,-3.227,2.058,5.42055,,H,A,1.1,-1.34,1.14,,63.99,PHB,-0.980667,0.221079,0.00193499,0.960673 Pab1_G177T,Pab1_177,Pab1,Pab1,P04147,0.960701,NO,177,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-2.24,-2.406,0.166,,,,,,,,,,AOH,-1.94067,0.175299,0.00170727,0.960701 beta-lactamase_39_D212S,beta-lactamase_39_212,TEM-1,beta-lactamase_39,P62593,0.960705,NO,212,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.624,-2.471,0.847,,0.037,,b,0.75,-0.58,10.748,10.748,74.48,HAB,-1.77667,0.0495842,0.00644302,0.960705 beta-lactamase_0_Y262K,beta-lactamase_0_262,TEM-1,beta-lactamase_0,P62593,0.960714,NO,262,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.0500837,0.00853516,0.960714 kka2_1:2_A191H,kka2_1:2_191,Kka2,kka2_1:2,P00552,0.960744,NO,191,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.831,-4.743,3.912,,,.,b,0.46,-0.94,2.046,,50,AHO,-0.868667,0.295029,0.00338807,0.960744 beta-lactamase_D250W,beta-lactamase_250,TEM-1,beta-lactamase,P62593,0.960745,NO,250,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.335,-5.6,3.265,5.72026,0.89,T,L,0.23,1.53,24.737,24.737,66.08,OAO,-1.85133,0.221079,0.00550899,0.960745 Pab1_D138C,Pab1_138,Pab1,Pab1,P04147,0.960749,NO,138,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.128,-5.008,3.88,,0.427,,B,,-0.03,,,,HAP,-1.13967,0.175299,0.000567877,0.960749 beta-lactamase_0_D99K,beta-lactamase_0_99,TEM-1,beta-lactamase_0,P62593,0.960757,NO,99,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.191,-3.447,2.256,,0.402,G,A,0.75,0.36,0.374,,64.69,PAH,-1.794,0.0500837,0.00305446,0.960757 beta-lactamase_A276T,beta-lactamase_276,TEM-1,beta-lactamase,P62593,0.960764,NO,276,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.144,-3.29,2.146,5.1387,0.117,H,A,0.52,-0.84,1.283,,44.06,HHA,-1.47,0.221079,0.0191712,0.960764 PSD95pdz3_N381R,PSD95pdz3_381,PSD95pdz3,PSD95pdz3,P31016,0.96077,NO,381,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-1.41,-3.165,1.755,5.66057,,,,,28.2162,,,,BPH,-1.37767,0.0758425,0.000265374,0.96077 kka2_1:2_P98A,kka2_1:2_98,Kka2,kka2_1:2,P00552,0.960779,NO,98,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.526,-2.324,0.798,,0.391,S,B,0.52,-0.65,2.82,,63.26,HOO,-1.19167,0.295029,0.00622754,0.960779 beta-lactamase_39_L28F,beta-lactamase_39_28,TEM-1,beta-lactamase_39,P62593,0.960786,NO,28,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.579,-3.916,2.337,,0.277,H,A,0.55,-0.16,3.262,,93.01,PHH,-2.11333,0.0495842,0.00359321,0.960786 beta-lactamase_39_M153G,beta-lactamase_39_153,TEM-1,beta-lactamase_39,P62593,0.960794,NO,153,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-3.193,-3.633,0.44,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.0495842,0.00509109,0.960794 PSD95pdz3_I377C,PSD95pdz3_377,PSD95pdz3,PSD95pdz3,P31016,0.960795,NO,377,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.873,-4.471,2.598,4.9532,,,,,19.185,2.364,,87.71,HHH,-1.49567,0.0758425,0.000795475,0.960795 beta-lactamase_A34C,beta-lactamase_34,TEM-1,beta-lactamase,P62593,0.960798,NO,34,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.059,-4.764,2.705,4.9129,,H,A,0.75,-0.54,3.614,,73.78,AHA,-1.74967,0.221079,0.00407913,0.960798 beta-lactamase_H285E,beta-lactamase_285,TEM-1,beta-lactamase,P62593,0.960798,NO,285,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-1.845,-2.22,0.375,5.64289,0.312,T,a,0.35,0.64,1.401,,72.73,BBH,-1.64567,0.221079,0.101555,0.960798 beta-lactamase_0_G90R,beta-lactamase_0_90,TEM-1,beta-lactamase_0,P62593,0.960807,NO,90,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-2.091,-3.098,1.007,,0.598,T,A,0.29,0.32,2.04,,77.62,HOB,-1.52633,0.0500837,0.00490273,0.960807 kka2_1:8_A64V,kka2_1:8_64,Kka2,kka2_1:8,P00552,0.960822,NO,64,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.496,-1.905,0.409,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.100394,0.00705578,0.960822 kka2_1:8_A64V,kka2_1:8_64,Kka2,kka2_1:8,P00552,0.960822,NO,64,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.496,-1.905,0.409,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.100394,0.00705578,0.960822 beta-lactamase_156_P143K,beta-lactamase_156_143,TEM-1,beta-lactamase_156,P62593,0.960843,NO,143,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.967,-3.581,2.614,,0.075,H,A,0.52,-0.37,0.479,,66.78,OOB,-1.354,0.111618,0.00114551,0.960843 beta-lactamase_156_L120H,beta-lactamase_156_120,TEM-1,beta-lactamase_156,P62593,0.960852,NO,120,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.044,-3.066,2.022,,,H,A,0.55,-1.13,7.813,,64.69,AHO,-1.13633,0.111618,0.00143563,0.960852 beta-lactamase_39_V101H,beta-lactamase_39_101,TEM-1,beta-lactamase_39,P62593,0.960875,NO,101,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.295,-4.92,3.625,,0.342,,B,0.44,0,2.96,,73.08,HHA,-1.54367,0.0495842,0.00374492,0.960875 beta-lactamase_39_E62Y,beta-lactamase_39_62,TEM-1,beta-lactamase_39,P62593,0.960878,NO,62,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.193,-4.285,3.092,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.0495842,0.00264802,0.960878 beta-lactamase_39_K30Y,beta-lactamase_39_30,TEM-1,beta-lactamase_39,P62593,0.960893,NO,30,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-2.307,-4.255,1.948,,0.142,H,A,2.34,-0.65,6.717,,93.01,HBH,-2.32833,0.0495842,0.00448593,0.960893 kka2_1:8_D134M,kka2_1:8_134,Kka2,kka2_1:8,P00552,0.960896,NO,134,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.969,-4.823,3.854,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.100394,0.00270812,0.960896 kka2_1:8_D134M,kka2_1:8_134,Kka2,kka2_1:8,P00552,0.960896,NO,134,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.969,-4.823,3.854,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.100394,0.00270812,0.960896 beta-lactamase_39_S256Q,beta-lactamase_39_256,TEM-1,beta-lactamase_39,P62593,0.960907,NO,256,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.0495842,0.00710634,0.960907 beta-lactamase_L55F,beta-lactamase_55,TEM-1,beta-lactamase,P62593,0.960953,NO,55,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.86,-2.527,0.667,,0.372,E,A,1.07,-0.36,1.423,,63.99,HHA,-2.247,0.221079,0.00403741,0.960953 beta-lactamase_625_A278D,beta-lactamase_625_278,TEM-1,beta-lactamase_625,P62593,0.960956,NO,278,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.213352,0.0310297,0.960956 beta-lactamase_0_L28V,beta-lactamase_0_28,TEM-1,beta-lactamase_0,P62593,0.960968,NO,28,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.579,-1.979,0.4,,0.277,H,A,0.55,-0.16,9.35,9.35,93.01,PHH,-2.11333,0.0500837,0.00359321,0.960968 beta-lactamase_39_E56Q,beta-lactamase_39_56,TEM-1,beta-lactamase_39,P62593,0.960969,NO,56,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.043,-3.697,1.654,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.0495842,0.00238534,0.960969 beta-lactamase_W163S,beta-lactamase_163,TEM-1,beta-lactamase,P62593,0.960979,NO,163,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-1.843,-3.614,1.771,6.2765,0.467,,B,1.22,-0.5,3.642,,63.99,BHA,-1.269,0.221079,0.00418955,0.960979 beta-lactamase_625_K213T,beta-lactamase_625_213,TEM-1,beta-lactamase_625,P62593,0.960983,NO,213,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.81,-2.431,0.621,,0.67,,A,2.34,0.29,3.924,,67.83,ABH,-1.57767,0.213352,0.00610411,0.960983 beta-lactamase_625_E56C,beta-lactamase_625_56,TEM-1,beta-lactamase_625,P62593,0.960985,NO,56,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.043,-4.827,2.784,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.213352,0.00238534,0.960985 beta-lactamase_A9A,beta-lactamase_9,TEM-1,beta-lactamase,P62593,0.960998,NO,9,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.147,-2.147,,,,,,,,5.128,,72.73,HHH,-2.04267,0.221079,0.00247263,0.960998 beta-lactamase_P12Q,beta-lactamase_12,TEM-1,beta-lactamase,P62593,0.960998,NO,12,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-2.016,-4.011,1.995,,,,,,,2.88,,72.73,HOH,-2.05167,0.221079,0.00241653,0.960998 beta-lactamase_2500_E145Y,beta-lactamase_2500_145,TEM-1,beta-lactamase_2500,P62593,0.961014,NO,145,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.357,-4.381,2.024,,0.545,H,A,1.04,0.79,2.124,,77.62,BAH,-2.069,0.361275,0.00553285,0.961014 kka2_1:2_D118T,kka2_1:2_118,Kka2,kka2_1:2,P00552,0.961025,NO,118,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.07,-2.449,0.379,,0.61,H,A,0.75,-0.05,2.237,,64.39,HAH,-1.32367,0.295029,0.0067852,0.961025 beta-lactamase_0_P217Q,beta-lactamase_0_217,TEM-1,beta-lactamase_0,P62593,0.961027,NO,217,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-2.062,-3.933,1.871,,0.496,I,A,0.52,-0.33,1.087,,74.48,OOH,-1.64333,0.0500837,0.00463211,0.961027 beta-lactamase_156_E272R,beta-lactamase_156_272,TEM-1,beta-lactamase_156,P62593,0.961034,NO,272,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.111618,0.00545371,0.961034 beta-lactamase_39_M153I,beta-lactamase_39_153,TEM-1,beta-lactamase_39,P62593,0.96105,NO,153,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-3.193,-1.739,-1.454,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.0495842,0.00509109,0.96105 beta-lactamase_156_E56Q,beta-lactamase_156_56,TEM-1,beta-lactamase_156,P62593,0.961054,NO,56,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.043,-3.697,1.654,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.111618,0.00238534,0.961054 beta-lactamase_2500_T178S,beta-lactamase_2500_178,TEM-1,beta-lactamase_2500,P62593,0.961067,NO,178,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-0.791,-2.936,2.145,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.361275,0.000684366,0.961067 beta-lactamase_156_G265I,beta-lactamase_156_265,TEM-1,beta-lactamase_156,P62593,0.961077,NO,265,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.111618,0.00811926,0.961077 kka2_1:8_L57K,kka2_1:8_57,Kka2,kka2_1:8,P00552,0.961081,NO,57,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.898,-3.894,1.996,,0.343,T,A,0.55,0.98,13.359,13.359,52.65,HHP,-2.20733,0.100394,0.00723769,0.961081 kka2_1:8_L57K,kka2_1:8_57,Kka2,kka2_1:8,P00552,0.961081,NO,57,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.898,-3.894,1.996,,0.343,T,A,0.55,0.98,13.359,13.359,52.65,HHP,-2.20733,0.100394,0.00723769,0.961081 beta-lactamase_2500_G90F,beta-lactamase_2500_90,TEM-1,beta-lactamase_2500,P62593,0.961082,NO,90,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-2.091,-4.407,2.316,,0.598,T,A,0.29,0.32,1.2,,77.62,HOB,-1.52633,0.361275,0.00490273,0.961082 kka2_1:2_P179L,kka2_1:2_179,Kka2,kka2_1:2,P00552,0.961114,NO,179,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.974,-2.273,1.299,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.295029,0.00298346,0.961114 beta-lactamase_625_D83G,beta-lactamase_625_83,TEM-1,beta-lactamase_625,P62593,0.961115,NO,83,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.066,-2.429,1.363,,0.354,H,A,0.75,0.22,0.239,,48.95,HAH,-1.34733,0.213352,0.00205968,0.961115 beta-lactamase_0_E119S,beta-lactamase_0_119,TEM-1,beta-lactamase_0,P62593,0.961145,NO,119,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.412,-2.681,1.269,,0.358,H,A,1.04,0.51,3.396,,63.99,BAH,-1.623,0.0500837,0.00386966,0.961145 beta-lactamase_C75T,beta-lactamase_75,TEM-1,beta-lactamase,P62593,0.961152,NO,75,C,T,CT,Special,Polar,5.07,5.6,0.53,149,121,119,-2,108.5,116.1,7.6,-1.245,-3.423,2.178,4.88171,,H,A,0.25,-0.87,0.876,,50,HOO,-1.24333,0.221079,0.0034616,0.961152 beta-lactamase_E277M,beta-lactamase_277,TEM-1,beta-lactamase,P62593,0.961152,NO,277,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.869,-4.856,2.987,5.51786,0.545,H,A,0.52,-0.01,2.022,,77.62,HAH,-1.45367,0.221079,0.0169305,0.961152 beta-lactamase_H5N,beta-lactamase_5,TEM-1,beta-lactamase,P62593,0.961152,NO,5,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-2.698,-3.773,1.075,,,,,,,1.865,,72.73,PBH,-2.36967,0.221079,0.00292712,0.961152 beta-lactamase_Q204K,beta-lactamase_204,TEM-1,beta-lactamase,P62593,0.961152,NO,204,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-1.382,-2.218,0.836,5.46394,0.204,H,A,0.12,0.09,1.707,,66.08,PPH,-1.49067,0.221079,0.00364106,0.961152 beta-lactamase_R118M,beta-lactamase_118,TEM-1,beta-lactamase,P62593,0.961152,NO,118,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.413,-4.747,2.334,5.8227,0.457,H,A,0.68,1.39,2.144,,77.62,HBA,-1.785,0.221079,0.00538794,0.961152 beta-lactamase_625_I140S,beta-lactamase_625_140,TEM-1,beta-lactamase_625,P62593,0.961153,NO,140,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.733,-3.688,1.955,,0.128,H,A,0.48,0.41,1.628,,73.08,PHO,-1.48733,0.213352,0.00597777,0.961153 beta-lactamase_0_T179K,beta-lactamase_0_179,TEM-1,beta-lactamase_0,P62593,0.961171,NO,179,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.085,-3.486,2.401,,,E,B,0.22,-1.38,0.367,,73.08,PPH,-1.557,0.0500837,0.00226045,0.961171 beta-lactamase_39_D161L,beta-lactamase_39_161,TEM-1,beta-lactamase_39,P62593,0.961191,NO,161,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.891,-3.777,2.886,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.0495842,0.000897697,0.961191 beta-lactamase_2500_Q203G,beta-lactamase_2500_203,TEM-1,beta-lactamase_2500,P62593,0.961197,NO,203,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.168,-2.805,0.637,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.361275,0.00631514,0.961197 beta-lactamase_2500_P217N,beta-lactamase_2500_217,TEM-1,beta-lactamase_2500,P62593,0.9612,NO,217,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-2.062,-2.997,0.935,,0.496,I,A,0.52,-0.33,0.431,,74.48,OOH,-1.64333,0.361275,0.00463211,0.9612 hsp90_F583H,hsp90_583,hsp90,hsp90,P02829,0.961207,NO,583,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-3.22,-3.833,0,5.28185,1.112,S,l,1.1,0.87,,,,PHO,-3.003,0.368192,0.000222939,0.961207 beta-lactamase_2500_E56Q,beta-lactamase_2500_56,TEM-1,beta-lactamase_2500,P62593,0.96121,NO,56,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.043,-3.697,1.654,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.361275,0.00238534,0.96121 beta-lactamase_39_D231G,beta-lactamase_39_231,TEM-1,beta-lactamase_39,P62593,0.961236,NO,231,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.816,-3.182,2.366,,,E,B,0.75,-1.06,0.462,,65.38,HAB,-0.994,0.0495842,0.00107395,0.961236 beta-lactamase_156_E195W,beta-lactamase_156_195,TEM-1,beta-lactamase_156,P62593,0.961252,NO,195,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.186,-5.555,3.369,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.111618,0.00496565,0.961252 gb1_F256L,gb1_256,gb1,gb1,P06654,0.961253,NO,256,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.241,-2.685,1.444,,,,,,,,,,HHB,-2.04767,0.177985,0.00435993,0.961253 Pab1_M189W,Pab1_189,Pab1,Pab1,P04147,0.961258,NO,189,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.406,-4.69,3.284,,0.631,E,b,,2.81,,,,OHH,-1.18,0.175299,0.000278756,0.961258 Pab1_N132G,Pab1_132,Pab1,Pab1,P04147,0.961269,NO,132,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-1.079,-2.725,1.646,,0.412,S,l,,0.9,,,,BPH,-1.067,0.175299,0.000347671,0.961269 beta-lactamase_39_V82D,beta-lactamase_39_82,TEM-1,beta-lactamase_39,P62593,0.961286,NO,82,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.325,-3.879,2.554,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.0495842,0.00397046,0.961286 beta-lactamase_F6Y,beta-lactamase_6,TEM-1,beta-lactamase,P62593,0.961286,NO,6,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.847,-3.551,1.704,,,,,,,1.276,,67.83,BHB,-2.076,0.221079,0.00261627,0.961286 beta-lactamase_39_D231R,beta-lactamase_39_231,TEM-1,beta-lactamase_39,P62593,0.961312,NO,231,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.816,-3.896,3.08,,,E,B,0.75,-1.06,0.462,,65.38,HAB,-0.994,0.0495842,0.00107395,0.961312 beta-lactamase_2500_A225L,beta-lactamase_2500_225,TEM-1,beta-lactamase_2500,P62593,0.961313,NO,225,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.845,-2.985,1.14,,1,T,B,0.46,-0.38,0.551,,74.48,OHO,-1.39967,0.361275,0.00465057,0.961313 beta-lactamase_2500_T198R,beta-lactamase_2500_198,TEM-1,beta-lactamase_2500,P62593,0.961316,NO,198,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.168,-3.752,1.584,,0.489,,B,0.22,-0.13,0.37,,73.78,HPH,-1.98767,0.361275,0.004311,0.961316 beta-lactamase_S96C,beta-lactamase_96,TEM-1,beta-lactamase,P62593,0.961318,NO,96,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.27,-5.145,2.875,5.29889,0.368,,b,0.25,0.39,32.348,32.348,73.78,HPP,-2.019,0.221079,0.00551835,0.961318 beta-lactamase_39_G216L,beta-lactamase_39_216,TEM-1,beta-lactamase_39,P62593,0.961335,NO,216,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.477,-3.78,2.303,,0.437,I,A,0.29,-0.58,0.834,,74.48,HOO,-1.68067,0.0495842,0.00639568,0.961335 beta-lactamase_0_T198K,beta-lactamase_0_198,TEM-1,beta-lactamase_0,P62593,0.961349,NO,198,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.168,-2.548,0.38,,0.489,,B,0.22,-0.13,9.874,,73.78,HPH,-1.98767,0.0500837,0.004311,0.961349 beta-lactamase_G85R,beta-lactamase_85,TEM-1,beta-lactamase,P62593,0.961359,NO,85,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.011,-2.784,1.773,5.58951,0.805,T,l,0.23,1.7,1.468,,63.64,HOP,-1.68733,0.221079,0.00252173,0.961359 beta-lactamase_39_E62L,beta-lactamase_39_62,TEM-1,beta-lactamase_39,P62593,0.961389,NO,62,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.193,-3.66,2.467,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.0495842,0.00264802,0.961389 beta-lactamase_625_T139H,beta-lactamase_625_139,TEM-1,beta-lactamase_625,P62593,0.961422,NO,139,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.901,-3.291,1.39,,0.216,H,A,0.22,0.39,2.256,,77.62,PPH,-2.04667,0.213352,0.00441837,0.961422 Pab1_T145M,Pab1_145,Pab1,Pab1,P04147,0.96146,NO,145,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.067,-4.297,3.23,,0.237,H,A,0.3,0.69,,,,APH,-1.135,0.175299,0.000331088,0.96146 PSD95pdz3_L367F,PSD95pdz3_367,PSD95pdz3,PSD95pdz3,P31016,0.961466,NO,367,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.347,-3.299,1.952,5.47696,,,,,17.0063,,,,AHB,-1.39767,0.0758425,0.000466436,0.961466 beta-lactamase_39_D99I,beta-lactamase_39_99,TEM-1,beta-lactamase_39,P62593,0.961467,NO,99,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.191,-3.979,2.788,,0.402,G,A,0.75,0.36,0.374,,64.69,PAH,-1.794,0.0495842,0.00305446,0.961467 beta-lactamase_H24L,beta-lactamase_24,TEM-1,beta-lactamase,P62593,0.961478,NO,24,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-2.481,-3.404,0.923,5.82767,,,,,,2.708,,93.01,HBO,-1.85167,0.221079,0.00238894,0.961478 beta-lactamase_M67S,beta-lactamase_67,TEM-1,beta-lactamase,P62593,0.961478,NO,67,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-2.231,-2.445,0.214,4.9618,0.006,G,P,1.07,-0.81,1.463,,65.03,HHP,-1.502,0.221079,0.00409753,0.961478 beta-lactamase_39_E62Q,beta-lactamase_39_62,TEM-1,beta-lactamase_39,P62593,0.96148,NO,62,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.193,-2.5,1.307,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.0495842,0.00264802,0.96148 Pab1_S165F,Pab1_165,Pab1,Pab1,P04147,0.961483,NO,165,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.146,-3.884,2.738,,0.12,,a,,0.11,,,,BPB,-1.56867,0.175299,0.000307838,0.961483 beta-lactamase_0_A247W,beta-lactamase_0_247,TEM-1,beta-lactamase_0,P62593,0.961492,NO,247,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.0500837,0.00611275,0.961492 Pab1_N139Q,Pab1_139,Pab1,Pab1,P04147,0.961499,NO,139,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-1.079,-3.491,2.412,,0.062,H,A,,-0.73,,,,APB,-1.09667,0.175299,0.000339145,0.961499 kka2_1:8_C192N,kka2_1:8_192,Kka2,kka2_1:8,P00552,0.961506,NO,192,C,N,CN,Special,Polar,5.07,5.47157,0.401575,139,121,132,11,108.5,114.1,5.6,-1.067,-3.983,2.916,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.100394,0.00485428,0.961506 kka2_1:8_C192N,kka2_1:8_192,Kka2,kka2_1:8,P00552,0.961506,NO,192,C,N,CN,Special,Polar,5.07,5.47157,0.401575,139,121,132,11,108.5,114.1,5.6,-1.067,-3.983,2.916,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.100394,0.00485428,0.961506 beta-lactamase_G251T,beta-lactamase_251,TEM-1,beta-lactamase,P62593,0.961512,NO,251,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.907,-2.747,0.84,5.33865,0.506,T,l,0.73,0.17,10.663,,65.38,AOB,-2.06067,0.221079,0.00733416,0.961512 kka2_1:4_A117V,kka2_1:4_117,Kka2,kka2_1:4,P00552,0.961512,NO,117,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.828,-2.25,1.422,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.168804,0.00282984,0.961512 beta-lactamase_156_A230W,beta-lactamase_156_230,TEM-1,beta-lactamase_156,P62593,0.961522,NO,230,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.154,-5.319,4.165,,0.01,E,B,0.46,-1.17,2.179,,50,HHA,-1.079,0.111618,0.00516841,0.961522 kka2_1:8_I115M,kka2_1:8_115,Kka2,kka2_1:8,P00552,0.961529,NO,115,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.606,-2.756,1.15,,0.105,H,A,1.52,-1.18,4.064,,65.53,PHH,-2.205,0.100394,0.00836567,0.961529 kka2_1:8_I115M,kka2_1:8_115,Kka2,kka2_1:8,P00552,0.961529,NO,115,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.606,-2.756,1.15,,0.105,H,A,1.52,-1.18,4.064,,65.53,PHH,-2.205,0.100394,0.00836567,0.961529 beta-lactamase_I3S,beta-lactamase_3,TEM-1,beta-lactamase,P62593,0.961547,NO,3,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-2.143,-3.319,1.176,,,,,,,3.946,,93.01,PHP,-2.21633,0.221079,0.00349304,0.961547 beta-lactamase_39_N274Y,beta-lactamase_39_274,TEM-1,beta-lactamase_39,P62593,0.961551,NO,274,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.0495842,0.0110418,0.961551 beta-lactamase_2500_D48E,beta-lactamase_2500_48,TEM-1,beta-lactamase_2500,P62593,0.961552,NO,48,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.101,-2.049,0.948,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.361275,0.0027273,0.961552 beta-lactamase_0_G154W,beta-lactamase_0_154,TEM-1,beta-lactamase_0,P62593,0.961574,NO,154,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.823,-5.233,4.41,,0.54,T,l,0.29,-0.56,3.629,,64.69,HOA,-1.635,0.0500837,0.00180205,0.961574 beta-lactamase_2500_L188F,beta-lactamase_2500_188,TEM-1,beta-lactamase_2500,P62593,0.961605,NO,188,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.166,-3.771,2.605,,,H,A,0.55,-0.3,17.865,17.865,60.14,PHB,-1.47033,0.361275,0.00295687,0.961605 beta-lactamase_G85D,beta-lactamase_85,TEM-1,beta-lactamase,P62593,0.96161,NO,85,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.011,-2.383,1.372,5.58951,0.805,T,l,0.23,1.7,1.468,,63.64,HOP,-1.68733,0.221079,0.00252173,0.96161 PSD95pdz3_N363W,PSD95pdz3_363,PSD95pdz3,PSD95pdz3,P31016,0.961615,NO,363,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-1.41,-5.229,3.819,5.23349,,,,,20.7037,,,,HPO,-1.29433,0.0758425,0.000524014,0.961615 beta-lactamase_39_L192N,beta-lactamase_39_192,TEM-1,beta-lactamase_39,P62593,0.961628,NO,192,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.254,-4.206,2.952,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.0495842,0.00558728,0.961628 gb1_A246N,gb1_246,gb1,gb1,P06654,0.961662,NO,246,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.175,-3.633,2.458,,,,,,,,,,AHH,-1.87033,0.177985,0.00190625,0.961662 gb1_Q258A,gb1_258,gb1,gb1,P06654,0.961662,NO,258,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.095,-2.128,0.033,,,,,,,0.86,,37.28,BPH,-1.88333,0.177985,0.00437595,0.961662 beta-lactamase_0_T112W,beta-lactamase_0_112,TEM-1,beta-lactamase_0,P62593,0.961691,NO,112,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.186,-5.474,3.288,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.0500837,0.00531334,0.961691 beta-lactamase_625_A247N,beta-lactamase_625_247,TEM-1,beta-lactamase_625,P62593,0.961698,NO,247,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.213352,0.00611275,0.961698 kka2_1:8_H162R,kka2_1:8_162,Kka2,kka2_1:8,P00552,0.961728,NO,162,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-2.319,-1.245,-1.074,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.100394,0.00616145,0.961728 kka2_1:8_H162R,kka2_1:8_162,Kka2,kka2_1:8,P00552,0.961728,NO,162,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-2.319,-1.245,-1.074,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.100394,0.00616145,0.961728 beta-lactamase_2500_S57R,beta-lactamase_2500_57,TEM-1,beta-lactamase_2500,P62593,0.961731,NO,57,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.918,-3.069,1.151,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.361275,0.00492804,0.961731 beta-lactamase_39_R275P,beta-lactamase_39_275,TEM-1,beta-lactamase_39,P62593,0.961739,NO,275,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.0495842,0.0141984,0.961739 beta-lactamase_156_A225K,beta-lactamase_156_225,TEM-1,beta-lactamase_156,P62593,0.961741,NO,225,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.845,-2.558,0.713,,1,T,B,0.46,-0.38,11.722,11.722,74.48,OHO,-1.39967,0.111618,0.00465057,0.961741 kka2_1:8_P167K,kka2_1:8_167,Kka2,kka2_1:8,P00552,0.961747,NO,167,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-2.403,-3.717,1.314,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.100394,0.00543203,0.961747 kka2_1:8_P167K,kka2_1:8_167,Kka2,kka2_1:8,P00552,0.961747,NO,167,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-2.403,-3.717,1.314,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.100394,0.00543203,0.961747 beta-lactamase_39_K144C,beta-lactamase_39_144,TEM-1,beta-lactamase_39,P62593,0.961749,NO,144,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-2.388,-5.107,2.719,,0.863,H,A,2.34,1.27,14.556,14.556,77.62,OBA,-1.904,0.0495842,0.00481141,0.961749 beta-lactamase_39_L284H,beta-lactamase_39_284,TEM-1,beta-lactamase_39,P62593,0.961763,NO,284,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.0495842,0.0686156,0.961763 beta-lactamase_0_T187W,beta-lactamase_0_187,TEM-1,beta-lactamase_0,P62593,0.961768,NO,187,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.401,-5.371,3.97,,0.007,H,A,0.22,-1.19,3.259,,67.48,PPH,-1.69633,0.0500837,0.00491782,0.961768 beta-lactamase_S254I,beta-lactamase_254,TEM-1,beta-lactamase,P62593,0.961778,NO,254,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.126,-4.017,1.891,5.49575,0.312,,a,0.25,-0.48,24.91,24.91,69.58,OPB,-2.215,0.221079,0.00369,0.961778 beta-lactamase_W163P,beta-lactamase_163,TEM-1,beta-lactamase,P62593,0.961778,NO,163,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-1.843,-4.201,2.358,6.2765,0.467,,B,1.22,-0.5,3.642,,63.99,BHA,-1.269,0.221079,0.00418955,0.961778 kka2_1:8_A9I,kka2_1:8_9,Kka2,kka2_1:8,P00552,0.961783,NO,9,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.079,-2.507,0.428,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.100394,0.00273264,0.961783 kka2_1:8_A9I,kka2_1:8_9,Kka2,kka2_1:8,P00552,0.961783,NO,9,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.079,-2.507,0.428,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.100394,0.00273264,0.961783 kka2_1:8_G55E,kka2_1:8_55,Kka2,kka2_1:8,P00552,0.961783,NO,55,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.625,-2.785,1.16,,0.517,S,b,0.29,1.19,8.881,,63.64,POH,-2.05967,0.100394,0.00667877,0.961783 kka2_1:8_G55E,kka2_1:8_55,Kka2,kka2_1:8,P00552,0.961783,NO,55,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.625,-2.785,1.16,,0.517,S,b,0.29,1.19,8.881,,63.64,POH,-2.05967,0.100394,0.00667877,0.961783 beta-lactamase_0_P165F,beta-lactamase_0_165,TEM-1,beta-lactamase_0,P62593,0.961812,NO,165,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.373,-4.322,2.949,,0.203,T,A,0.52,-0.31,3.242,,73.78,AOA,-1.359,0.0500837,0.00549538,0.961812 beta-lactamase_39_G39K,beta-lactamase_39_39,TEM-1,beta-lactamase_39,P62593,0.961821,NO,39,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.864,-2.703,0.839,,0.701,T,L,0.29,0.47,1.454,,77.62,HOH,-1.53633,0.0495842,0.00487611,0.961821 kka2_1:4_A64G,kka2_1:4_64,Kka2,kka2_1:4,P00552,0.961834,NO,64,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.496,-2.776,1.28,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.168804,0.00705578,0.961834 beta-lactamase_39_P165E,beta-lactamase_39_165,TEM-1,beta-lactamase_39,P62593,0.961848,NO,165,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.373,-3.511,2.138,,0.203,T,A,0.52,-0.31,3.907,,73.78,AOA,-1.359,0.0495842,0.00549538,0.961848 beta-lactamase_39_M115A,beta-lactamase_39_115,TEM-1,beta-lactamase_39,P62593,0.961849,NO,115,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.389,-2.535,1.146,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.0495842,0.0034337,0.961849 beta-lactamase_2500_S57M,beta-lactamase_2500_57,TEM-1,beta-lactamase_2500,P62593,0.961858,NO,57,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.918,-4.684,2.766,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.361275,0.00492804,0.961858 beta-lactamase_0_G265M,beta-lactamase_0_265,TEM-1,beta-lactamase_0,P62593,0.961882,NO,265,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.0500837,0.00811926,0.961882 beta-lactamase_39_V82Y,beta-lactamase_39_82,TEM-1,beta-lactamase_39,P62593,0.961892,NO,82,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.325,-4.133,2.808,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.0495842,0.00397046,0.961892 Pab1_G177Y,Pab1_177,Pab1,Pab1,P04147,0.961892,NO,177,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-2.24,-4.193,1.953,,,,,,,,,,AOH,-1.94067,0.175299,0.00170727,0.961892 beta-lactamase_39_K144L,beta-lactamase_39_144,TEM-1,beta-lactamase_39,P62593,0.961898,NO,144,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-2.388,-3.577,1.189,,0.863,H,A,2.34,1.27,14.556,14.556,77.62,OBA,-1.904,0.0495842,0.00481141,0.961898 beta-lactamase_39_E62A,beta-lactamase_39_62,TEM-1,beta-lactamase_39,P62593,0.961901,NO,62,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.193,-2.533,1.34,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.0495842,0.00264802,0.961901 kka2_1:4_K138W,kka2_1:4_138,Kka2,kka2_1:4,P00552,0.961909,NO,138,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-2.5,-5.6,3.1,,0.594,H,A,1.3,0.98,21.267,21.267,71.59,HBB,-2.48833,0.168804,0.00628542,0.961909 beta-lactamase_39_I261C,beta-lactamase_39_261,TEM-1,beta-lactamase_39,P62593,0.961919,NO,261,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.0495842,0.0123091,0.961919 PSD95pdz3_A382D,PSD95pdz3_382,PSD95pdz3,PSD95pdz3,P31016,0.96193,NO,382,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.307,-3.375,2.068,5.30282,,,,,22.472,,,,PHO,-1.24167,0.0758425,0.000249256,0.96193 PSD95pdz3_A370N,PSD95pdz3_370,PSD95pdz3,PSD95pdz3,P31016,0.961935,NO,370,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.307,-3.58,2.273,5.22304,,,,,17.284,,,,PHP,-1.57967,0.0758425,0.000429106,0.961935 kka2_1:8_M120T,kka2_1:8_120,Kka2,kka2_1:8,P00552,0.961943,NO,120,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-3.877,-3.448,-0.429,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.100394,0.00265808,0.961943 kka2_1:8_M120T,kka2_1:8_120,Kka2,kka2_1:8,P00552,0.961943,NO,120,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-3.877,-3.448,-0.429,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.100394,0.00265808,0.961943 beta-lactamase_39_D231W,beta-lactamase_39_231,TEM-1,beta-lactamase_39,P62593,0.961954,NO,231,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.816,-5.545,4.729,,,E,B,0.75,-1.06,0.462,,65.38,HAB,-0.994,0.0495842,0.00107395,0.961954 beta-lactamase_0_N50E,beta-lactamase_0_50,TEM-1,beta-lactamase_0,P62593,0.961971,NO,50,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-2.979,-2.315,-0.664,,0.912,T,A,0.61,1.24,9.874,9.874,77.62,HPP,-2.134,0.0500837,0.0047211,0.961971 E1_Ubiquitin_A46A,E1_Ubiquitin_46,Uba1,E1_Ubiquitin,P0CG63,0.961981,NO,46,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.367,-1.367,,,0.398,T,L,,-0.8,,,,HHO,-1.17167,0.18783,0.004233,0.961981 E1_Ubiquitin_T68V,E1_Ubiquitin_68,Uba1,E1_Ubiquitin,P0CG63,0.961981,NO,68,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,,,,,,,,,,,,,OPH,-1.039,0.18783,0.00314321,0.961981 beta-lactamase_0_G114F,beta-lactamase_0_114,TEM-1,beta-lactamase_0,P62593,0.962008,NO,114,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.094,-4.331,3.237,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.0500837,0.00224919,0.962008 beta-lactamase_2500_G90L,beta-lactamase_2500_90,TEM-1,beta-lactamase_2500,P62593,0.962013,NO,90,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-2.091,-3.689,1.598,,0.598,T,A,0.29,0.32,1.2,,77.62,HOB,-1.52633,0.361275,0.00490273,0.962013 beta-lactamase_156_P224F,beta-lactamase_156_224,TEM-1,beta-lactamase_156,P62593,0.962021,NO,224,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.893,-4.486,3.593,,0.383,,B,0.52,-0.3,0.383,,74.48,HOH,-1.26433,0.111618,0.00189564,0.962021 beta-lactamase_Q86W,beta-lactamase_86,TEM-1,beta-lactamase,P62593,0.962057,NO,86,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.4,-5.489,3.089,5.39897,0.696,S,A,0.12,2.38,2.105,,77.62,OPA,-1.61067,0.221079,0.00450027,0.962057 Pab1_G188T,Pab1_188,Pab1,Pab1,P04147,0.962084,NO,188,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.809,-3.464,2.655,,0.379,E,g,,2.18,,,,POH,-1.14633,0.175299,0.000280911,0.962084 beta-lactamase_0_R220Q,beta-lactamase_0_220,TEM-1,beta-lactamase_0,P62593,0.962085,NO,220,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-0.942,-3.517,2.575,,0.295,I,A,1.2,-0.76,21.573,21.573,74.48,HBP,-1.33633,0.0500837,0.00232421,0.962085 kka2_1:8_A119T,kka2_1:8_119,Kka2,kka2_1:8,P00552,0.962085,NO,119,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.073,-3.309,2.236,,0.019,H,A,0.46,-0.57,1.511,,71.59,AHH,-2.34,0.100394,0.00441074,0.962085 kka2_1:8_A119T,kka2_1:8_119,Kka2,kka2_1:8,P00552,0.962085,NO,119,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.073,-3.309,2.236,,0.019,H,A,0.46,-0.57,1.511,,71.59,AHH,-2.34,0.100394,0.00441074,0.962085 beta-lactamase_39_I206F,beta-lactamase_39_206,TEM-1,beta-lactamase_39,P62593,0.962089,NO,206,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-2.429,-4.165,1.736,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.0495842,0.00528934,0.962089 beta-lactamase_39_D231Y,beta-lactamase_39_231,TEM-1,beta-lactamase_39,P62593,0.96209,NO,231,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.816,-4.385,3.569,,,E,B,0.75,-1.06,0.462,,65.38,HAB,-0.994,0.0495842,0.00107395,0.96209 beta-lactamase_156_L146M,beta-lactamase_156_146,TEM-1,beta-lactamase_156,P62593,0.962092,NO,146,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.462,-4.183,2.721,,0.007,H,A,0.55,-0.56,1.578,,64.69,AHP,-1.656,0.111618,0.00474542,0.962092 PSD95pdz3_A378Q,PSD95pdz3_378,PSD95pdz3,PSD95pdz3,P31016,0.962092,NO,378,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.307,-3.581,2.274,4.86582,,,,,14.576,,,,HHH,-1.509,0.0758425,0.000313169,0.962092 Pab1_A185L,Pab1_185,Pab1,Pab1,P04147,0.962097,NO,185,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.702,-3.348,1.646,,,,,,,1.756,,63.26,AHH,-1.66167,0.175299,0.00144499,0.962097 beta-lactamase_156_A123M,beta-lactamase_156_123,TEM-1,beta-lactamase_156,P62593,0.962107,NO,123,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.834,-4.443,3.609,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.111618,0.0010157,0.962107 beta-lactamase_39_V214A,beta-lactamase_39_214,TEM-1,beta-lactamase_39,P62593,0.962108,NO,214,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.299,-2.434,1.135,,0.375,S,A,0.44,-0.44,18.838,18.838,74.48,BHH,-1.53733,0.0495842,0.00628442,0.962108 beta-lactamase_P20P,beta-lactamase_20,TEM-1,beta-lactamase,P62593,0.962118,NO,20,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.74,-1.74,,,,,,,,0.368,,67.83,HOH,-1.765,0.221079,0.00235322,0.962118 PSD95pdz3_V362Y,PSD95pdz3_362,PSD95pdz3,PSD95pdz3,P31016,0.962126,NO,362,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.465,-3.619,2.154,4.99436,,,,,19.6443,,,,PHP,-1.46467,0.0758425,0.000538527,0.962126 beta-lactamase_156_D212W,beta-lactamase_156_212,TEM-1,beta-lactamase_156,P62593,0.962137,NO,212,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.624,-5.54,3.916,,0.037,,b,0.75,-0.58,20.222,20.222,74.48,HAB,-1.77667,0.111618,0.00644302,0.962137 beta-lactamase_2500_A222I,beta-lactamase_2500_222,TEM-1,beta-lactamase_2500,P62593,0.96214,NO,222,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.103,-3.632,1.529,,0.233,H,A,0.46,-0.25,0.379,,77.62,PHH,-1.63733,0.361275,0.00466094,0.96214 PSD95pdz3_I377N,PSD95pdz3_377,PSD95pdz3,PSD95pdz3,P31016,0.962141,NO,377,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.873,-3.957,2.084,4.9532,,,,,19.185,2.364,,87.71,HHH,-1.49567,0.0758425,0.000795475,0.962141 beta-lactamase_V8E,beta-lactamase_8,TEM-1,beta-lactamase,P62593,0.962145,NO,8,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-2.358,-3.645,1.287,,,,,,,0.575,,77.62,BHH,-2.06267,0.221079,0.00226401,0.962145 beta-lactamase_2500_D271K,beta-lactamase_2500_271,TEM-1,beta-lactamase_2500,P62593,0.962154,NO,271,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.361275,0.00752082,0.962154 PSD95pdz3_K380Y,PSD95pdz3_380,PSD95pdz3,PSD95pdz3,P31016,0.962154,NO,380,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.416,-3.844,2.428,5.87979,,,,,19.6722,,,,HBP,-1.391,0.0758425,0.000281399,0.962154 beta-lactamase_2500_D271F,beta-lactamase_2500_271,TEM-1,beta-lactamase_2500,P62593,0.962161,NO,271,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.361275,0.00752082,0.962161 beta-lactamase_2500_K144P,beta-lactamase_2500_144,TEM-1,beta-lactamase_2500,P62593,0.962165,NO,144,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-2.388,-2.633,0.245,,0.863,H,A,2.34,1.27,0.515,,77.62,OBA,-1.904,0.361275,0.00481141,0.962165 PSD95pdz3_L379I,PSD95pdz3_379,PSD95pdz3,PSD95pdz3,P31016,0.96217,NO,379,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.347,-2.567,1.22,5.37777,,,,,16.8762,,,,HHB,-1.35667,0.0758425,0.00029733,0.96217 kka2_1:8_A108I,kka2_1:8_108,Kka2,kka2_1:8,P00552,0.96218,NO,108,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.061,-3.962,1.901,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.100394,0.00751209,0.96218 kka2_1:8_A108I,kka2_1:8_108,Kka2,kka2_1:8,P00552,0.96218,NO,108,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.061,-3.962,1.901,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.100394,0.00751209,0.96218 Pab1_G188H,Pab1_188,Pab1,Pab1,P04147,0.962185,NO,188,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.809,-4.497,3.688,,0.379,E,g,,2.18,,,,POH,-1.14633,0.175299,0.000280911,0.962185 beta-lactamase_2500_G226N,beta-lactamase_2500_226,TEM-1,beta-lactamase_2500,P62593,0.96219,NO,226,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.461,-2.628,1.167,,0.701,T,l,0.29,-0.25,5.086,,74.48,HOH,-1.42933,0.361275,0.00665294,0.96219 beta-lactamase_W163T,beta-lactamase_163,TEM-1,beta-lactamase,P62593,0.962214,NO,163,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-1.843,-2.765,0.922,6.2765,0.467,,B,1.22,-0.5,3.642,,63.99,BHA,-1.269,0.221079,0.00418955,0.962214 beta-lactamase_K252L,beta-lactamase_252,TEM-1,beta-lactamase,P62593,0.962231,NO,252,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.94,-3.662,1.722,5.56823,0.766,,B,1.82,1.16,21.796,21.796,67.83,OBO,-2.03333,0.221079,0.00575769,0.962231 beta-lactamase_39_M153W,beta-lactamase_39_153,TEM-1,beta-lactamase_39,P62593,0.96225,NO,153,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-3.193,-5.376,2.183,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.0495842,0.00509109,0.96225 beta-lactamase_156_L197N,beta-lactamase_156_197,TEM-1,beta-lactamase_156,P62593,0.962272,NO,197,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.853,-4.12,3.267,,0.007,S,B,0.55,0.33,1.58,,60.14,HHP,-1.833,0.111618,0.00144602,0.962272 Pab1_F146V,Pab1_146,Pab1,Pab1,P04147,0.962272,NO,146,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.149,-3.121,1.972,,0.006,H,A,,0.75,,,,PHP,-1.161,0.175299,0.000329265,0.962272 gb1_A260S,gb1_260,gb1,gb1,P06654,0.962273,NO,260,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.486,-3.083,1.597,,,,,,,0.173,,9.6,HHP,-1.70967,0.177985,0.0055808,0.962273 gb1_Y229L,gb1_229,gb1,gb1,P06654,0.962273,NO,229,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-1.282,-2.869,1.587,,,,,,,,,,PHB,-1.4915,0.177985,0.00366605,0.962273 beta-lactamase_0_N98Q,beta-lactamase_0_98,TEM-1,beta-lactamase_0,P62593,0.962303,NO,98,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-2.973,-2.336,-0.637,,0.963,G,A,0.61,1.35,14.853,14.853,77.62,PPA,-2.07867,0.0500837,0.00505389,0.962303 beta-lactamase_0_M184V,beta-lactamase_0_184,TEM-1,beta-lactamase_0,P62593,0.962308,NO,184,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.593,-2.346,0.753,,,H,A,0.55,-0.87,13.292,13.292,62.94,HHH,-1.41,0.0500837,0.00356019,0.962308 beta-lactamase_39_A268T,beta-lactamase_39_268,TEM-1,beta-lactamase_39,P62593,0.96231,NO,268,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.0495842,0.0102525,0.96231 beta-lactamase_0_R162F,beta-lactamase_0_162,TEM-1,beta-lactamase_0,P62593,0.962314,NO,162,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.016,-4.266,3.25,,0.124,S,B,1.2,-0.37,1.026,,64.69,ABH,-1.25,0.0500837,0.000561334,0.962314 beta-lactamase_V157L,beta-lactamase_157,TEM-1,beta-lactamase,P62593,0.962315,NO,157,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.751,-3.066,1.315,5.51733,0.308,S,a,0.96,-0.75,1.847,,69.58,BHP,-2.00767,0.221079,0.00506849,0.962315 beta-lactamase_39_W288Q,beta-lactamase_39_288,TEM-1,beta-lactamase_39,P62593,0.962334,NO,288,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,,,,,,,,,,,,,BHO,,0.0495842,,0.962334 beta-lactamase_39_D231L,beta-lactamase_39_231,TEM-1,beta-lactamase_39,P62593,0.962346,NO,231,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.816,-3.806,2.99,,,E,B,0.75,-1.06,0.462,,65.38,HAB,-0.994,0.0495842,0.00107395,0.962346 beta-lactamase_156_S51K,beta-lactamase_156_51,TEM-1,beta-lactamase_156,P62593,0.96235,NO,51,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.526,-3.459,1.933,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.111618,0.00504821,0.96235 beta-lactamase_2500_T264Q,beta-lactamase_2500_264,TEM-1,beta-lactamase_2500,P62593,0.962367,NO,264,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.361275,0.0119399,0.962367 beta-lactamase_2500_M180A,beta-lactamase_2500_180,TEM-1,beta-lactamase_2500,P62593,0.962378,NO,180,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-2.795,-2.974,0.179,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.361275,0.00552048,0.962378 kka2_1:1_M1V,kka2_1:1_1,Kka2,kka2_1:1,P00552,0.962392,NO,1,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.787,-1.867,0.08,,,,,,,3.101,,62.12,NAHH,-1.787,0.520039,0.00251939,0.962392 beta-lactamase_625_V260L,beta-lactamase_625_260,TEM-1,beta-lactamase_625,P62593,0.962395,NO,260,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.213352,0.00471757,0.962395 kka2_1:4_S104G,kka2_1:4_104,Kka2,kka2_1:4,P00552,0.962427,NO,104,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.436,-3.347,1.911,,0.536,T,A,0.27,-1.11,0.357,,63.64,HPP,-1.91433,0.168804,0.00555207,0.962427 beta-lactamase_39_G39I,beta-lactamase_39_39,TEM-1,beta-lactamase_39,P62593,0.962428,NO,39,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.864,-4.195,2.331,,0.701,T,L,0.29,0.47,1.454,,77.62,HOH,-1.53633,0.0495842,0.00487611,0.962428 beta-lactamase_Q88C,beta-lactamase_88,TEM-1,beta-lactamase,P62593,0.962438,NO,88,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.086,-5.138,3.052,5.8056,0.807,,B,0.12,2.03,1.84,,77.62,APH,-1.53433,0.221079,0.00504167,0.962438 beta-lactamase_0_L73K,beta-lactamase_0_73,TEM-1,beta-lactamase_0,P62593,0.962439,NO,73,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.507,-3.846,2.339,,,H,A,0.55,-0.64,0.877,,67.83,HHH,-1.487,0.0500837,0.00488983,0.962439 beta-lactamase_625_L199Y,beta-lactamase_625_199,TEM-1,beta-lactamase_625,P62593,0.962443,NO,199,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-2.942,-4.431,1.489,,0.832,H,A,0.55,0.42,1.552,,77.62,PHH,-2.32933,0.213352,0.0048649,0.962443 PSD95pdz3_G364C,PSD95pdz3_364,PSD95pdz3,PSD95pdz3,P31016,0.96246,NO,364,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.008,-4.769,3.761,5.53299,,,,,21.28,,,,POH,-1.33667,0.0758425,0.00050942,0.96246 beta-lactamase_S96M,beta-lactamase_96,TEM-1,beta-lactamase,P62593,0.962478,NO,96,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.27,-3.49,1.22,5.29889,0.368,,b,0.25,0.39,32.348,32.348,73.78,HPP,-2.019,0.221079,0.00551835,0.962478 kka2_1:1_H106P,kka2_1:1_106,Kka2,kka2_1:1,P00552,0.96249,NO,106,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-3.13,-2.907,-0.223,,1.065,.,a,0.17,-0.95,2.53,,71.59,PBH,-2.10433,0.520039,0.00730778,0.96249 beta-lactamase_0_Y103T,beta-lactamase_0_103,TEM-1,beta-lactamase_0,P62593,0.962504,NO,103,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-1.33,-3.696,2.366,,0.613,S,l,0.21,1.21,1.646,,63.29,AHP,-1.48767,0.0500837,0.00443048,0.962504 beta-lactamase_156_L146F,beta-lactamase_156_146,TEM-1,beta-lactamase_156,P62593,0.962504,NO,146,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.462,-2.298,0.836,,0.007,H,A,0.55,-0.56,1.578,,64.69,AHP,-1.656,0.111618,0.00474542,0.962504 beta-lactamase_2500_R275F,beta-lactamase_2500_275,TEM-1,beta-lactamase_2500,P62593,0.962517,NO,275,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.361275,0.0141984,0.962517 beta-lactamase_2500_I277L,beta-lactamase_2500_277,TEM-1,beta-lactamase_2500,P62593,0.962527,NO,277,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.361275,0.0169305,0.962527 beta-lactamase_L135V,beta-lactamase_135,TEM-1,beta-lactamase,P62593,0.962556,NO,135,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.002,-2.8,1.798,5.28497,0.117,H,A,1.07,-0.58,0.697,,43.71,PHH,-1.03767,0.221079,0.00244423,0.962556 beta-lactamase_39_L120Y,beta-lactamase_39_120,TEM-1,beta-lactamase_39,P62593,0.962569,NO,120,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.044,-3.856,2.812,,,H,A,0.55,-1.13,22.254,22.254,64.69,AHO,-1.13633,0.0495842,0.00143563,0.962569 Pab1_E174R,Pab1_174,Pab1,Pab1,P04147,0.962573,NO,174,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.422,-2.382,0.96,,0.578,S,A,,0.38,,,,HAA,-1.65133,0.175299,0.00077863,0.962573 WW_domain_R187S,WW_domain_187,Yap65,WW_domain,P46937,0.962605,NO,187,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.402,-3.156,1.754,5.05189,,,,,,3.431,,78.57,PBH,-1.362,0.153962,0.00171149,0.962605 beta-lactamase_2500_M127I,beta-lactamase_2500_127,TEM-1,beta-lactamase_2500,P62593,0.962614,NO,127,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-2.251,-2.439,0.188,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.361275,0.00437927,0.962614 beta-lactamase_2500_A148Y,beta-lactamase_2500_148,TEM-1,beta-lactamase_2500,P62593,0.962624,NO,148,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.757,-4.336,2.579,,0.379,H,A,0.46,-0.55,2.117,,72.73,PHH,-1.40167,0.361275,0.00547053,0.962624 hsp90_E590V,hsp90_590,hsp90,hsp90,P02829,0.962624,NO,590,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.818,-2.682,0,4.65049,0.021,H,A,,0.03,,,,HAO,-3.338,0.368192,0.000222939,0.962624 Pab1_V148T,Pab1_148,Pab1,Pab1,P04147,0.962627,NO,148,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.875,-1.849,-0.026,,,,,,,,,,PHH,-1.43033,0.175299,0.00179641,0.962627 beta-lactamase_A222P,beta-lactamase_222,TEM-1,beta-lactamase,P62593,0.962633,NO,222,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.103,-2.971,0.868,5.2262,0.233,H,A,0.47,-0.25,0.379,,77.62,PHH,-1.63733,0.221079,0.00466094,0.962633 beta-lactamase_M67V,beta-lactamase_67,TEM-1,beta-lactamase,P62593,0.96266,NO,67,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-2.231,-2.772,0.541,4.9618,0.006,G,P,1.07,-0.81,1.463,,65.03,HHP,-1.502,0.221079,0.00409753,0.96266 beta-lactamase_39_A170T,beta-lactamase_39_170,TEM-1,beta-lactamase_39,P62593,0.962663,NO,170,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.237,-3.423,2.186,,0.126,,L,0.46,-0.35,3.7,,64.69,AHH,-1.63267,0.0495842,0.00431903,0.962663 beta-lactamase_P217H,beta-lactamase_217,TEM-1,beta-lactamase,P62593,0.96267,NO,217,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-2.062,-3.354,1.292,5.19872,0.496,I,A,0.99,-0.33,0.431,,74.48,OOH,-1.64333,0.221079,0.00463211,0.96267 Pab1_S147A,Pab1_147,Pab1,Pab1,P04147,0.962683,NO,147,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.267,-2.548,1.281,,0.336,H,A,,0.56,,,,HPH,-1.43033,0.175299,0.000610856,0.962683 kka2_1:4_E230N,kka2_1:4_230,Kka2,kka2_1:4,P00552,0.962694,NO,230,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.672,-3.821,1.149,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.168804,0.00920051,0.962694 beta-lactamase_0_D155P,beta-lactamase_0_155,TEM-1,beta-lactamase_0,P62593,0.96271,NO,155,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.889,-3.725,2.836,,0.049,,B,0.75,-0.9,16.833,16.833,64.69,OAB,-1.62267,0.0500837,0.00135315,0.96271 beta-lactamase_39_D83T,beta-lactamase_39_83,TEM-1,beta-lactamase_39,P62593,0.96274,NO,83,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.066,-3.464,2.398,,0.354,H,A,0.75,0.22,0.752,,48.95,HAH,-1.34733,0.0495842,0.00205968,0.96274 beta-lactamase_156_E56H,beta-lactamase_156_56,TEM-1,beta-lactamase_156,P62593,0.962753,NO,56,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.043,-4.467,2.424,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.111618,0.00238534,0.962753 beta-lactamase_39_D231S,beta-lactamase_39_231,TEM-1,beta-lactamase_39,P62593,0.962759,NO,231,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.816,-3.186,2.37,,,E,B,0.75,-1.06,0.462,,65.38,HAB,-0.994,0.0495842,0.00107395,0.962759 kka2_1:8_H162C,kka2_1:8_162,Kka2,kka2_1:8,P00552,0.96276,NO,162,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-2.319,-5.188,2.869,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.100394,0.00616145,0.96276 kka2_1:8_H162C,kka2_1:8_162,Kka2,kka2_1:8,P00552,0.96276,NO,162,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-2.319,-5.188,2.869,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.100394,0.00616145,0.96276 beta-lactamase_625_K213E,beta-lactamase_625_213,TEM-1,beta-lactamase_625,P62593,0.962778,NO,213,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.81,-2.688,0.878,,0.67,,A,2.34,0.29,3.924,,67.83,ABH,-1.57767,0.213352,0.00610411,0.962778 beta-lactamase_T112M,beta-lactamase_112,TEM-1,beta-lactamase,P62593,0.962781,NO,112,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.186,-4.812,2.626,6.47162,0.921,T,A,0.77,1.06,2.04,,73.78,HPA,-1.925,0.221079,0.00531334,0.962781 beta-lactamase_T262C,beta-lactamase_262,TEM-1,beta-lactamase,P62593,0.962781,NO,262,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.332,-4.79,3.458,5.06002,0.108,E,B,0.3,-0.55,1.423,,67.83,PPO,-2.081,0.221079,0.00853516,0.962781 kka2_1:2_S40D,kka2_1:2_40,Kka2,kka2_1:2,P00552,0.962821,NO,40,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.645,-2.229,-0.416,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.295029,0.00693477,0.962821 beta-lactamase_156_I285N,beta-lactamase_156_285,TEM-1,beta-lactamase_156,P62593,0.962828,NO,285,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.111618,0.101555,0.962828 Pab1_N192R,Pab1_192,Pab1,Pab1,P04147,0.962832,NO,192,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-1.079,-3.3,2.221,,0.619,T,l,,2.28,,,,HPO,-1.231,0.175299,0.000273498,0.962832 beta-lactamase_2500_E169W,beta-lactamase_2500_169,TEM-1,beta-lactamase_2500,P62593,0.96284,NO,169,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.23,-5.379,4.149,,0.337,,A,1.04,1,1.806,,73.08,PAH,-1.16533,0.361275,0.00400994,0.96284 beta-lactamase_2500_Q203S,beta-lactamase_2500_203,TEM-1,beta-lactamase_2500,P62593,0.962843,NO,203,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.168,-2.824,0.656,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.361275,0.00631514,0.962843 PSD95pdz3_E331N,PSD95pdz3_331,PSD95pdz3,PSD95pdz3,P31016,0.962847,NO,331,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.404,-3.13,1.726,5.86289,,,,,51.8889,,,,OAA,-1.22533,0.0758425,0.000950134,0.962847 kka2_1:4_R122S,kka2_1:4_122,Kka2,kka2_1:4,P00552,0.96285,NO,122,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.175,-2.833,0.658,,0.487,H,A,0.16,0.26,16.436,16.436,71.59,BBH,-1.53833,0.168804,0.00736512,0.96285 kka2_1:8_D134S,kka2_1:8_134,Kka2,kka2_1:8,P00552,0.962852,NO,134,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.969,-2.62,1.651,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.100394,0.00270812,0.962852 kka2_1:8_D134S,kka2_1:8_134,Kka2,kka2_1:8,P00552,0.962852,NO,134,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.969,-2.62,1.651,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.100394,0.00270812,0.962852 beta-lactamase_625_P172I,beta-lactamase_625_172,TEM-1,beta-lactamase_625,P62593,0.962861,NO,172,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.998,-3.854,2.856,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.213352,0.00312594,0.962861 beta-lactamase_2500_M180K,beta-lactamase_2500_180,TEM-1,beta-lactamase_2500,P62593,0.962873,NO,180,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-2.795,-3.525,0.73,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.361275,0.00552048,0.962873 beta-lactamase_0_G43A,beta-lactamase_0_43,TEM-1,beta-lactamase_0,P62593,0.962877,NO,43,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.62,-2.853,2.233,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.0500837,0.00120151,0.962877 kka2_1:2_P98Q,kka2_1:2_98,Kka2,kka2_1:2,P00552,0.962889,NO,98,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.526,-3.169,1.643,,0.391,S,B,0.52,-0.65,2.82,,63.26,HOO,-1.19167,0.295029,0.00622754,0.962889 beta-lactamase_39_R81K,beta-lactamase_39_81,TEM-1,beta-lactamase_39,P62593,0.962893,NO,81,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.466,-2.393,0.927,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.0495842,0.00499763,0.962893 WW_domain_M179V,WW_domain_179,Yap65,WW_domain,P46937,0.962894,NO,179,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.541,-2.631,1.09,6.54704,,,,,,,,,AHH,-1.31367,0.153962,0.00400164,0.962894 beta-lactamase_G85S,beta-lactamase_85,TEM-1,beta-lactamase,P62593,0.962903,NO,85,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.011,-3.264,2.253,5.58951,0.805,T,l,0.23,1.7,1.468,,63.64,HOP,-1.68733,0.221079,0.00252173,0.962903 beta-lactamase_39_M153V,beta-lactamase_39_153,TEM-1,beta-lactamase_39,P62593,0.962909,NO,153,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-3.193,-2.524,-0.669,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.0495842,0.00509109,0.962909 beta-lactamase_2500_K109F,beta-lactamase_2500_109,TEM-1,beta-lactamase_2500,P62593,0.96291,NO,109,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.734,-4.437,2.703,,0.787,G,A,2.34,2.21,0.998,,72.73,ABB,-1.63333,0.361275,0.00462493,0.96291 beta-lactamase_E277S,beta-lactamase_277,TEM-1,beta-lactamase,P62593,0.96295,NO,277,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.869,-3.339,1.47,5.51786,0.545,H,A,0.52,-0.01,2.022,,77.62,HAH,-1.45367,0.221079,0.0169305,0.96295 kka2_1:8_D183V,kka2_1:8_183,Kka2,kka2_1:8,P00552,0.962999,NO,183,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.204,-2.92,1.716,,0.518,.,b,0.75,0.25,0.347,,52.27,AAH,-1.40533,0.100394,0.00426304,0.962999 kka2_1:8_D183V,kka2_1:8_183,Kka2,kka2_1:8,P00552,0.962999,NO,183,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.204,-2.92,1.716,,0.518,.,b,0.75,0.25,0.347,,52.27,AAH,-1.40533,0.100394,0.00426304,0.962999 beta-lactamase_2500_D271Y,beta-lactamase_2500_271,TEM-1,beta-lactamase_2500,P62593,0.963006,NO,271,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.361275,0.00752082,0.963006 beta-lactamase_39_Q203P,beta-lactamase_39_203,TEM-1,beta-lactamase_39,P62593,0.963009,NO,203,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.168,-3.941,1.773,,0.47,H,A,0.64,-0.38,1.453,,65.38,BPP,-1.614,0.0495842,0.00631514,0.963009 beta-lactamase_2500_C75A,beta-lactamase_2500_75,TEM-1,beta-lactamase_2500,P62593,0.963013,NO,75,C,A,CA,Special,Hydrophobic,5.07,6,0.93,195,121,89,-32,108.5,88.6,-19.9,-1.245,-1.87,0.625,,,H,A,0.46,-0.87,0.844,,50,HOO,-1.24333,0.361275,0.0034616,0.963013 beta-lactamase_2500_A133T,beta-lactamase_2500_133,TEM-1,beta-lactamase_2500,P62593,0.963017,NO,133,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.186,-2.382,1.196,,,H,A,0.46,-0.86,2.649,,67.83,HHP,-0.988333,0.361275,0.00468022,0.963017 kka2_1:8_L259T,kka2_1:8_259,Kka2,kka2_1:8,P00552,0.963017,NO,259,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.088,-2.444,1.356,,0.036,H,A,1.59,-0.15,1.83,,48.48,BHH,-1.15167,0.100394,0.0206964,0.963017 kka2_1:8_L259T,kka2_1:8_259,Kka2,kka2_1:8,P00552,0.963017,NO,259,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.088,-2.444,1.356,,0.036,H,A,1.59,-0.15,1.83,,48.48,BHH,-1.15167,0.100394,0.0206964,0.963017 PSD95pdz3_F325Y,PSD95pdz3_325,PSD95pdz3,PSD95pdz3,P31016,0.963017,NO,325,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.524,-2.719,1.195,5.50654,,,,,12.7236,,,,OHP,-1.314,0.0758425,0.00102273,0.963017 beta-lactamase_156_L218D,beta-lactamase_156_218,TEM-1,beta-lactamase_156,P62593,0.963042,NO,218,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.391,-3.905,2.514,,,I,b,0.55,-0.53,17.202,17.202,74.48,OHH,-1.58867,0.111618,0.00618274,0.963042 beta-lactamase_39_R41F,beta-lactamase_39_41,TEM-1,beta-lactamase_39,P62593,0.963061,NO,41,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-0.942,-4.29,3.348,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.0495842,0.00123327,0.963061 Pab1_A199V,Pab1_199,Pab1,Pab1,P04147,0.963072,NO,199,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.53,-3.285,1.755,,,,,,,1.479,,80.42,HHO,-1.50467,0.175299,0.00145024,0.963072 beta-lactamase_2500_R91K,beta-lactamase_2500_91,TEM-1,beta-lactamase_2500,P62593,0.963079,NO,91,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.392,-2.505,1.113,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.361275,0.00380226,0.963079 beta-lactamase_39_G142L,beta-lactamase_39_142,TEM-1,beta-lactamase_39,P62593,0.9631,NO,142,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.707,-3.771,3.064,,0.034,,p,0.29,-0.64,1.947,,64.69,OOO,-0.834,0.0495842,0.00060149,0.9631 beta-lactamase_39_D271H,beta-lactamase_39_271,TEM-1,beta-lactamase_39,P62593,0.963118,NO,271,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.0495842,0.00752082,0.963118 beta-lactamase_S2S,beta-lactamase_2,TEM-1,beta-lactamase,P62593,0.96314,NO,2,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.942,-1.942,,,,,,,,2.36,,65.38,HPH,-2.02767,0.221079,0.00227352,0.96314 beta-lactamase_156_G216N,beta-lactamase_156_216,TEM-1,beta-lactamase_156,P62593,0.963147,NO,216,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.477,-2.771,1.294,,0.437,I,A,0.29,-0.58,12.464,12.464,74.48,HOO,-1.68067,0.111618,0.00639568,0.963147 beta-lactamase_39_Y44T,beta-lactamase_39_44,TEM-1,beta-lactamase_39,P62593,0.963154,NO,44,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-2.547,-2.836,0.289,,,E,B,0.21,-0.45,2.683,,73.78,OHH,-1.86267,0.0495842,0.00426364,0.963154 PSD95pdz3_Q374Y,PSD95pdz3_374,PSD95pdz3,PSD95pdz3,P31016,0.963173,NO,374,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-1.699,-3.619,1.92,5.38825,,,,,17.3289,,,,APH,-1.47,0.0758425,0.000372298,0.963173 beta-lactamase_625_I277Y,beta-lactamase_625_277,TEM-1,beta-lactamase_625,P62593,0.963177,NO,277,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.213352,0.0169305,0.963177 beta-lactamase_0_E210D,beta-lactamase_0_210,TEM-1,beta-lactamase_0,P62593,0.963178,NO,210,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.319,-3.702,1.383,,0.476,H,A,1.04,0.75,3.618,,77.62,HAH,-1.88567,0.0500837,0.00663582,0.963178 beta-lactamase_39_L89G,beta-lactamase_39_89,TEM-1,beta-lactamase_39,P62593,0.963183,NO,89,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.096,-3.653,2.557,,0.168,T,A,0.55,0.63,3.233,,64.34,PHO,-1.75767,0.0495842,0.00207068,0.963183 beta-lactamase_2500_A200L,beta-lactamase_2500_200,TEM-1,beta-lactamase_2500,P62593,0.963188,NO,200,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.878,-3.527,1.649,,0.757,H,A,0.46,-0.19,0.436,,77.62,HHP,-2.001,0.361275,0.0060056,0.963188 beta-lactamase_A77K,beta-lactamase_77,TEM-1,beta-lactamase,P62593,0.963188,NO,77,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.234,-3.628,2.394,4.75777,0.039,H,A,0.52,-0.56,1.708,,64.34,OHH,-1.294,0.221079,0.00282362,0.963188 beta-lactamase_E119G,beta-lactamase_119,TEM-1,beta-lactamase,P62593,0.963188,NO,119,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.412,-2.405,0.993,5.33349,0.358,H,A,1.52,0.51,1.983,,63.99,BAH,-1.623,0.221079,0.00386966,0.963188 beta-lactamase_E46N,beta-lactamase_46,TEM-1,beta-lactamase,P62593,0.963188,NO,46,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.94,-4.011,2.071,5.36461,0.021,E,B,1.51,0.14,0.373,,59.44,HAH,-2.079,0.221079,0.00427568,0.963188 beta-lactamase_F64F,beta-lactamase_64,TEM-1,beta-lactamase,P62593,0.963188,NO,64,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-0.841,-0.841,,5.70769,0.006,E,B,1.33,-0.95,,,,BHO,-0.892667,0.221079,0.000947691,0.963188 beta-lactamase_K252G,beta-lactamase_252,TEM-1,beta-lactamase,P62593,0.963188,NO,252,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.94,-2.181,0.241,5.56823,0.766,,B,1.82,1.16,21.796,21.796,67.83,OBO,-2.03333,0.221079,0.00575769,0.963188 beta-lactamase_M153H,beta-lactamase_153,TEM-1,beta-lactamase,P62593,0.963188,NO,153,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-3.193,-4.946,1.753,5.46509,0.14,T,A,1.07,-0.11,2.061,,77.62,PHO,-2.25767,0.221079,0.00509109,0.963188 beta-lactamase_Q88G,beta-lactamase_88,TEM-1,beta-lactamase,P62593,0.963188,NO,88,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.086,-3.448,1.362,5.8056,0.807,,B,0.12,2.03,1.84,,77.62,APH,-1.53433,0.221079,0.00504167,0.963188 beta-lactamase_156_D212Y,beta-lactamase_156_212,TEM-1,beta-lactamase_156,P62593,0.963199,NO,212,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.624,-4.398,2.774,,0.037,,b,0.75,-0.58,20.222,20.222,74.48,HAB,-1.77667,0.111618,0.00644302,0.963199 beta-lactamase_625_K30Y,beta-lactamase_625_30,TEM-1,beta-lactamase_625,P62593,0.963199,NO,30,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-2.307,-4.255,1.948,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.213352,0.00448593,0.963199 beta-lactamase_0_L218I,beta-lactamase_0_218,TEM-1,beta-lactamase_0,P62593,0.963211,NO,218,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.391,-3.447,2.056,,,I,b,0.55,-0.53,28.707,28.707,74.48,OHH,-1.58867,0.0500837,0.00618274,0.963211 Pab1_E175L,Pab1_175,Pab1,Pab1,P04147,0.963213,NO,175,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.055,-3.511,1.456,,,,,,,,,,AAA,-1.82667,0.175299,0.00203137,0.963213 Pab1_H134S,Pab1_134,Pab1,Pab1,P04147,0.963215,NO,134,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-1.542,-3.161,1.619,,,,,,,,,,HBO,-1.346,0.175299,0.00116356,0.963215 Pab1_E174L,Pab1_174,Pab1,Pab1,P04147,0.963218,NO,174,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.422,-3.484,2.062,,0.578,S,A,,0.38,,,,HAA,-1.65133,0.175299,0.00077863,0.963218 beta-lactamase_0_G249Y,beta-lactamase_0_249,TEM-1,beta-lactamase_0,P62593,0.963219,NO,249,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.0500837,0.00220169,0.963219 beta-lactamase_625_G226L,beta-lactamase_625_226,TEM-1,beta-lactamase_625,P62593,0.963223,NO,226,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.461,-3.765,2.304,,0.701,T,l,0.29,-0.25,3.199,,74.48,HOH,-1.42933,0.213352,0.00665294,0.963223 beta-lactamase_S221E,beta-lactamase_221,TEM-1,beta-lactamase,P62593,0.963228,NO,221,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.754,-3.442,1.688,5.77407,0.624,H,A,0.74,-0.2,0.383,,74.48,BPH,-1.59967,0.221079,0.0046094,0.963228 beta-lactamase_39_N98E,beta-lactamase_39_98,TEM-1,beta-lactamase_39,P62593,0.963244,NO,98,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-2.973,-2.445,-0.528,,0.963,G,A,0.61,1.35,14.853,14.853,77.62,PPA,-2.07867,0.0495842,0.00505389,0.963244 beta-lactamase_2500_K254Y,beta-lactamase_2500_254,TEM-1,beta-lactamase_2500,P62593,0.963257,NO,254,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.361275,0.00369,0.963257 kka2_1:1_L123R,kka2_1:1_123,Kka2,kka2_1:1,P00552,0.963281,NO,123,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.888,-4.001,3.113,,0.007,H,A,0.55,-0.4,1.447,,48.86,BHB,-1.301,0.520039,0.00325188,0.963281 beta-lactamase_T107A,beta-lactamase_107,TEM-1,beta-lactamase,P62593,0.963282,NO,107,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.117,-2.274,1.157,5.23432,,G,A,2.12,-0.06,3.676,,67.83,HPA,-1.265,0.221079,0.00239347,0.963282 beta-lactamase_39_D161H,beta-lactamase_39_161,TEM-1,beta-lactamase_39,P62593,0.963286,NO,161,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.891,-4.479,3.588,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.0495842,0.000897697,0.963286 Pab1_E181A,Pab1_181,Pab1,Pab1,P04147,0.963291,NO,181,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.767,-1.565,-0.202,,,,,,,1.395,,73.83,BAH,-1.575,0.175299,0.00107557,0.963291 beta-lactamase_39_M153S,beta-lactamase_39_153,TEM-1,beta-lactamase_39,P62593,0.963294,NO,153,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-3.193,-2.433,-0.76,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.0495842,0.00509109,0.963294 beta-lactamase_156_V78Q,beta-lactamase_156_78,TEM-1,beta-lactamase_156,P62593,0.9633,NO,78,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.459,-4.26,2.801,,,H,A,0.44,-0.47,1.132,,63.64,HHH,-1.17833,0.111618,0.00492501,0.9633 beta-lactamase_156_E195V,beta-lactamase_156_195,TEM-1,beta-lactamase_156,P62593,0.963309,NO,195,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.186,-3.798,1.612,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.111618,0.00496565,0.963309 beta-lactamase_T131A,beta-lactamase_131,TEM-1,beta-lactamase,P62593,0.963313,NO,131,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.328,-2.085,0.757,5.0548,,H,A,0.53,-0.69,3.306,,67.48,PPH,-1.00867,0.221079,0.00345886,0.963313 beta-lactamase_39_E210Y,beta-lactamase_39_210,TEM-1,beta-lactamase_39,P62593,0.963317,NO,210,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.319,-4.214,1.895,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.0495842,0.00663582,0.963317 beta-lactamase_39_Q86L,beta-lactamase_39_86,TEM-1,beta-lactamase_39,P62593,0.963338,NO,86,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.4,-2.558,0.158,,0.696,S,A,0.64,2.38,27.704,27.704,77.62,OPA,-1.61067,0.0495842,0.00450027,0.963338 beta-lactamase_2500_F58S,beta-lactamase_2500_58,TEM-1,beta-lactamase_2500,P62593,0.963342,NO,58,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-2.914,-2.895,-0.019,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.361275,0.00523369,0.963342 beta-lactamase_39_D155Q,beta-lactamase_39_155,TEM-1,beta-lactamase_39,P62593,0.963347,NO,155,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.889,-3.667,2.778,,0.049,,B,0.75,-0.9,3.208,,64.69,OAB,-1.62267,0.0495842,0.00135315,0.963347 beta-lactamase_156_G281N,beta-lactamase_156_281,TEM-1,beta-lactamase_156,P62593,0.963353,NO,281,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.111618,0.0406482,0.963353 beta-lactamase_39_S256W,beta-lactamase_39_256,TEM-1,beta-lactamase_39,P62593,0.963362,NO,256,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.0495842,0.00710634,0.963362 beta-lactamase_E237W,beta-lactamase_237,TEM-1,beta-lactamase,P62593,0.963373,NO,237,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.058,-5.518,3.46,5.42877,0.583,S,B,1.62,1.2,2.144,,77.62,OAB,-1.61467,0.221079,0.0048626,0.963373 beta-lactamase_2500_I285F,beta-lactamase_2500_285,TEM-1,beta-lactamase_2500,P62593,0.963377,NO,285,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.361275,0.101555,0.963377 beta-lactamase_2500_G154E,beta-lactamase_2500_154,TEM-1,beta-lactamase_2500,P62593,0.963382,NO,154,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.823,-3.512,2.689,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.361275,0.00180205,0.963382 beta-lactamase_S80D,beta-lactamase_80,TEM-1,beta-lactamase,P62593,0.963389,NO,80,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.029,-2.7,0.671,5.23748,0.192,H,A,0.25,0.46,2.256,,77.62,HPB,-1.44567,0.221079,0.00565569,0.963389 beta-lactamase_2500_E279S,beta-lactamase_2500_279,TEM-1,beta-lactamase_2500,P62593,0.963395,NO,279,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.361275,0.0192826,0.963395 kka2_1:4_R44L,kka2_1:4_44,Kka2,kka2_1:4,P00552,0.963411,NO,44,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.062,-2.371,0.309,,0.487,S,B,1.2,-0.35,5.71,,71.59,OBO,-1.80767,0.168804,0.00745043,0.963411 PSD95pdz3_A378D,PSD95pdz3_378,PSD95pdz3,PSD95pdz3,P31016,0.963445,NO,378,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.307,-3.375,2.068,4.86582,,,,,14.576,,,,HHH,-1.509,0.0758425,0.000313169,0.963445 beta-lactamase_625_F228I,beta-lactamase_625_228,TEM-1,beta-lactamase_625,P62593,0.963466,NO,228,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-2.342,-3.049,0.707,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.213352,0.0046669,0.963466 beta-lactamase_625_M67C,beta-lactamase_625_67,TEM-1,beta-lactamase_625,P62593,0.963477,NO,67,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-2.231,-2.364,0.133,,0.006,G,P,0.55,-0.81,2.653,,65.03,HHP,-1.502,0.213352,0.00409753,0.963477 gb1_K276M,gb1_276,gb1,gb1,P06654,0.963489,NO,276,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.456,-4.32,2.864,,,,,,,0.236,,12.72,PBP,-1.65133,0.177985,0.00620493,0.963489 beta-lactamase_2500_D33L,beta-lactamase_2500_33,TEM-1,beta-lactamase_2500,P62593,0.963522,NO,33,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.321,-2.326,0.005,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.361275,0.00435556,0.963522 beta-lactamase_0_A183N,beta-lactamase_0_183,TEM-1,beta-lactamase_0,P62593,0.963537,NO,183,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.231,-2.504,1.273,,0.155,H,A,0.46,-0.91,1.48,,77.62,HHH,-1.53367,0.0500837,0.00296631,0.963537 beta-lactamase_G90F,beta-lactamase_90,TEM-1,beta-lactamase,P62593,0.963547,NO,90,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-2.091,-4.407,2.316,5.51991,0.598,T,A,0.23,0.32,1.791,,77.62,HOB,-1.52633,0.221079,0.00490273,0.963547 kka2_1:2_E161A,kka2_1:2_161,Kka2,kka2_1:2,P00552,0.963559,NO,161,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.581,-1.927,0.346,,0.829,G,A,1.52,2.24,1.612,,92.05,AAB,-1.861,0.295029,0.00760103,0.963559 kka2_1:2_L223I,kka2_1:2_223,Kka2,kka2_1:2,P00552,0.96357,NO,223,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.861,-2.071,1.21,,,H,A,0.55,-1.24,0.266,,50,HHH,-0.854333,0.295029,0.00253574,0.96357 Pab1_E181G,Pab1_181,Pab1,Pab1,P04147,0.963578,NO,181,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.767,-3.041,1.274,,,,,,,1.395,,73.83,BAH,-1.575,0.175299,0.00107557,0.963578 PSD95pdz3_D332S,PSD95pdz3_332,PSD95pdz3,PSD95pdz3,P31016,0.963582,NO,332,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.264,-2.842,1.578,6.09878,,,,,48.762,,,,AAO,-1.22533,0.0758425,0.000937818,0.963582 beta-lactamase_0_C75R,beta-lactamase_0_75,TEM-1,beta-lactamase_0,P62593,0.963586,NO,75,C,R,CR,Special,PositiveCharge,5.07,6.34148,1.27148,180,121,174,53,108.5,173.4,64.9,-1.245,-4.065,2.82,,,H,A,0.46,-0.87,2.256,,50,HOO,-1.24333,0.0500837,0.0034616,0.963586 beta-lactamase_0_K32Q,beta-lactamase_0_32,TEM-1,beta-lactamase_0,P62593,0.963587,NO,32,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.984,-2.601,0.617,,0.563,H,A,2.34,0.34,0.418,,73.08,HBA,-2.04233,0.0500837,0.00401283,0.963587 beta-lactamase_0_G52S,beta-lactamase_0_52,TEM-1,beta-lactamase_0,P62593,0.9636,NO,52,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.149,-2.647,1.498,,0.299,,l,0.29,-0.04,1.164,,64.69,POB,-1.66267,0.0500837,0.00340138,0.9636 beta-lactamase_39_A170S,beta-lactamase_39_170,TEM-1,beta-lactamase_39,P62593,0.963615,NO,170,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.237,-3.188,1.951,,0.126,,L,0.46,-0.35,3.7,,64.69,AHH,-1.63267,0.0495842,0.00431903,0.963615 beta-lactamase_39_D36C,beta-lactamase_39_36,TEM-1,beta-lactamase_39,P62593,0.963615,NO,36,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.732,-5.131,2.399,,0.555,H,A,0.75,1.17,13.689,13.689,77.62,AAP,-1.91167,0.0495842,0.00476483,0.963615 beta-lactamase_0_L55R,beta-lactamase_0_55,TEM-1,beta-lactamase_0,P62593,0.963622,NO,55,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.86,-3.1,1.24,,0.372,E,A,0.55,-0.36,1.967,,63.99,HHA,-2.247,0.0500837,0.00403741,0.963622 kka2_1:8_V80N,kka2_1:8_80,Kka2,kka2_1:8,P00552,0.963623,NO,80,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.144,-4.197,3.053,,0.358,E,B,1.48,-0.24,2.562,,63.64,HHH,-1.64633,0.100394,0.00488211,0.963623 kka2_1:8_V80N,kka2_1:8_80,Kka2,kka2_1:8,P00552,0.963623,NO,80,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.144,-4.197,3.053,,0.358,E,B,1.48,-0.24,2.562,,63.64,HHH,-1.64633,0.100394,0.00488211,0.963623 beta-lactamase_39_K144Y,beta-lactamase_39_144,TEM-1,beta-lactamase_39,P62593,0.963642,NO,144,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-2.388,-4.321,1.933,,0.863,H,A,2.34,1.27,14.556,14.556,77.62,OBA,-1.904,0.0495842,0.00481141,0.963642 kka2_1:4_P167D,kka2_1:4_167,Kka2,kka2_1:4,P00552,0.963665,NO,167,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-2.403,-3.015,0.612,,0.18,H,A,0.52,0.75,3.6,,64.39,HOH,-2.26633,0.168804,0.00543203,0.963665 kka2_1:2_T225Y,kka2_1:2_225,Kka2,kka2_1:2,P00552,0.963667,NO,225,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.393,-4.28,1.887,,0.036,H,A,0.22,-1.22,4.554,,63.64,HPB,-1.58733,0.295029,0.0113598,0.963667 beta-lactamase_39_E169I,beta-lactamase_39_169,TEM-1,beta-lactamase_39,P62593,0.963668,NO,169,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.23,-3.986,2.756,,0.337,,A,1.04,1,15.633,15.633,73.08,PAH,-1.16533,0.0495842,0.00400994,0.963668 beta-lactamase_R92H,beta-lactamase_92,TEM-1,beta-lactamase,P62593,0.963671,NO,92,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.718,-4.618,2.9,5.65832,0.479,E,B,0.91,1.36,3.069,,65.38,BBH,-1.50367,0.221079,0.00429626,0.963671 gb1_G235A,gb1_235,gb1,gb1,P06654,0.963691,NO,235,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.419,-2.664,1.245,,,,,,,0.476,,11.83,POB,-1.86433,0.177985,0.00297491,0.963691 gb1_T281W,gb1_281,gb1,gb1,P06654,0.963691,NO,281,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.828,-5.13,3.302,,,,,,,1.038,,35.71,HPA,-1.63667,0.177985,0.00284418,0.963691 kka2_1:2_Y218D,kka2_1:2_218,Kka2,kka2_1:2,P00552,0.963693,NO,218,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-1.438,-3.939,2.501,,0.122,H,A,0.21,-0.69,1.022,,56.06,BHP,-1.17533,0.295029,0.0126098,0.963693 beta-lactamase_156_M115V,beta-lactamase_156_115,TEM-1,beta-lactamase_156,P62593,0.963695,NO,115,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.389,-3.055,1.666,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.111618,0.0034337,0.963695 beta-lactamase_0_A182D,beta-lactamase_0_182,TEM-1,beta-lactamase_0,P62593,0.963704,NO,182,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.777,-2.705,0.928,,0.136,H,A,0.46,-0.66,10.765,10.765,93.01,OHH,-1.27367,0.0500837,0.00559099,0.963704 beta-lactamase_39_G243Q,beta-lactamase_39_243,TEM-1,beta-lactamase_39,P62593,0.963719,NO,243,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.0495842,0.00464034,0.963719 beta-lactamase_I11A,beta-lactamase_11,TEM-1,beta-lactamase,P62593,0.963729,NO,11,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.745,-3.04,1.295,,,,,,,3.135,,66.08,HHO,-1.79467,0.221079,0.00261325,0.963729 WW_domain_A175N,WW_domain_175,Yap65,WW_domain,P46937,0.963743,NO,175,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.631,-3.631,2,6.69537,,,,,,6.257,,83.93,OHO,-1.30033,0.153962,0.00326874,0.963743 beta-lactamase_0_V259W,beta-lactamase_0_259,TEM-1,beta-lactamase_0,P62593,0.963745,NO,259,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.0500837,0.0070773,0.963745 E1_Ubiquitin_L43C,E1_Ubiquitin_43,Uba1,E1_Ubiquitin,P0CG63,0.963749,NO,43,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.188,-4.508,3.32,,,E,B,,-1.17,,,,BHH,-1.30733,0.18783,0.00190185,0.963749 E1_Ubiquitin_L43V,E1_Ubiquitin_43,Uba1,E1_Ubiquitin,P0CG63,0.963749,NO,43,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.188,-2.774,1.586,,,E,B,,-1.17,,,,BHH,-1.30733,0.18783,0.00190185,0.963749 beta-lactamase_0_D271Y,beta-lactamase_0_271,TEM-1,beta-lactamase_0,P62593,0.96375,NO,271,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.0500837,0.00752082,0.96375 beta-lactamase_2500_E166I,beta-lactamase_2500_166,TEM-1,beta-lactamase_2500,P62593,0.963751,NO,166,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.756,-3.874,2.118,,0.508,G,A,1.04,1.05,2.124,,73.08,OAH,-1.42233,0.361275,0.00512989,0.963751 kka2_1:8_D82H,kka2_1:8_82,Kka2,kka2_1:8,P00552,0.963752,NO,82,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.946,-4.75,2.804,,0.341,E,b,0.29,0.52,7.463,,63.64,HAH,-1.98,0.100394,0.00637516,0.963752 kka2_1:8_D82H,kka2_1:8_82,Kka2,kka2_1:8,P00552,0.963752,NO,82,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.946,-4.75,2.804,,0.341,E,b,0.29,0.52,7.463,,63.64,HAH,-1.98,0.100394,0.00637516,0.963752 PSD95pdz3_Q374D,PSD95pdz3_374,PSD95pdz3,PSD95pdz3,P31016,0.963781,NO,374,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-1.699,-2.925,1.226,5.38825,,,,,17.3289,,,,APH,-1.47,0.0758425,0.000372298,0.963781 beta-lactamase_39_G90D,beta-lactamase_39_90,TEM-1,beta-lactamase_39,P62593,0.963791,NO,90,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-2.091,-2.02,-0.071,,0.598,T,A,0.29,0.32,30.794,30.794,77.62,HOB,-1.52633,0.0495842,0.00490273,0.963791 beta-lactamase_39_M180T,beta-lactamase_39_180,TEM-1,beta-lactamase_39,P62593,0.963812,NO,180,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-2.795,-1.278,-1.517,,0.242,,B,0.55,-0.94,3.579,,77.62,PHO,-1.56433,0.0495842,0.00552048,0.963812 beta-lactamase_2500_T147R,beta-lactamase_2500_147,TEM-1,beta-lactamase_2500,P62593,0.963818,NO,147,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.149,-3.809,2.66,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.361275,0.00226017,0.963818 Pab1_D184N,Pab1_184,Pab1,Pab1,P04147,0.963835,NO,184,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.5,-3.23,1.73,,,,,,,,,,HAH,-1.50133,0.175299,0.0011931,0.963835 kka2_1:8_D227G,kka2_1:8_227,Kka2,kka2_1:8,P00552,0.963844,NO,227,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.758,-3.04,1.282,,0.128,H,A,0.75,-0.63,0.281,,56.06,BAH,-1.43067,0.100394,0.00745029,0.963844 kka2_1:8_D227G,kka2_1:8_227,Kka2,kka2_1:8,P00552,0.963844,NO,227,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.758,-3.04,1.282,,0.128,H,A,0.75,-0.63,0.281,,56.06,BAH,-1.43067,0.100394,0.00745029,0.963844 beta-lactamase_0_K254I,beta-lactamase_0_254,TEM-1,beta-lactamase_0,P62593,0.963846,NO,254,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.0500837,0.00369,0.963846 beta-lactamase_39_G90I,beta-lactamase_39_90,TEM-1,beta-lactamase_39,P62593,0.96385,NO,90,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-2.091,-4.052,1.961,,0.598,T,A,0.29,0.32,30.794,30.794,77.62,HOB,-1.52633,0.0495842,0.00490273,0.96385 beta-lactamase_39_L191F,beta-lactamase_39_191,TEM-1,beta-lactamase_39,P62593,0.963862,NO,191,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.087,-2.754,1.667,,,H,A,0.55,0.09,1.372,,63.29,BHH,-1.445,0.0495842,0.00263549,0.963862 beta-lactamase_P60P,beta-lactamase_60,TEM-1,beta-lactamase,P62593,0.963867,NO,60,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-2.469,-2.469,,5.51353,0.256,T,A,0.73,-0.56,3.653,,77.62,BOA,-1.97633,0.221079,0.00521318,0.963867 beta-lactamase_R189M,beta-lactamase_189,TEM-1,beta-lactamase,P62593,0.963867,NO,189,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.844,-4.718,2.874,5.74877,0.278,H,A,0.68,1.01,1.512,,72.73,HBB,-1.668,0.221079,0.0050699,0.963867 beta-lactamase_39_E169S,beta-lactamase_39_169,TEM-1,beta-lactamase_39,P62593,0.963877,NO,169,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.23,-2.21,0.98,,0.337,,A,1.04,1,15.633,15.633,73.08,PAH,-1.16533,0.0495842,0.00400994,0.963877 beta-lactamase_39_D252Y,beta-lactamase_39_252,TEM-1,beta-lactamase_39,P62593,0.963878,NO,252,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.0495842,0.00575769,0.963878 beta-lactamase_39_T147Q,beta-lactamase_39_147,TEM-1,beta-lactamase_39,P62593,0.963878,NO,147,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.149,-3.979,2.83,,0.281,H,A,0.22,-0.68,13.843,13.843,64.34,HPH,-1.456,0.0495842,0.00226017,0.963878 beta-lactamase_625_I54D,beta-lactamase_625_54,TEM-1,beta-lactamase_625,P62593,0.96389,NO,54,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-2.838,-3.732,0.894,,0.669,E,B,0.48,-0.14,3.946,,73.78,BHH,-2.337,0.213352,0.00403589,0.96389 kka2_1:2_V83L,kka2_1:2_83,Kka2,kka2_1:2,P00552,0.963893,NO,83,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-2.567,-2.63,0.063,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.295029,0.00650486,0.963893 beta-lactamase_2500_T269K,beta-lactamase_2500_269,TEM-1,beta-lactamase_2500,P62593,0.963899,NO,269,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.361275,0.00950944,0.963899 beta-lactamase_2500_E87V,beta-lactamase_2500_87,TEM-1,beta-lactamase_2500,P62593,0.963906,NO,87,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.421,-2.385,0.964,,0.048,,B,1.04,0.92,17.923,17.923,64.69,PAP,-1.969,0.361275,0.00337888,0.963906 beta-lactamase_39_G90W,beta-lactamase_39_90,TEM-1,beta-lactamase_39,P62593,0.963931,NO,90,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-2.091,-5.515,3.424,,0.598,T,A,0.29,0.32,30.794,30.794,77.62,HOB,-1.52633,0.0495842,0.00490273,0.963931 Pab1_D184C,Pab1_184,Pab1,Pab1,P04147,0.963935,NO,184,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.5,-5.094,3.594,,,,,,,,,,HAH,-1.50133,0.175299,0.0011931,0.963935 beta-lactamase_0_L79F,beta-lactamase_0_79,TEM-1,beta-lactamase_0,P62593,0.963945,NO,79,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.842,-3.643,2.801,,0.007,H,A,0.55,-0.16,5.053,,50.35,HHP,-1.44333,0.0500837,0.000947397,0.963945 beta-lactamase_2500_T269C,beta-lactamase_2500_269,TEM-1,beta-lactamase_2500,P62593,0.963956,NO,269,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.361275,0.00950944,0.963956 beta-lactamase_0_G249P,beta-lactamase_0_249,TEM-1,beta-lactamase_0,P62593,0.963957,NO,249,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.312,-2.663,1.351,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.0500837,0.00220169,0.963957 Pab1_F168Y,Pab1_168,Pab1,Pab1,P04147,0.963959,NO,168,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.269,-2.031,0.762,,,,,,,0.789,,56.33,OHO,-1.10033,0.175299,0.00064061,0.963959 beta-lactamase_2500_S256L,beta-lactamase_2500_256,TEM-1,beta-lactamase_2500,P62593,0.963963,NO,256,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.361275,0.00710634,0.963963 kka2_1:2_Q42C,kka2_1:2_42,Kka2,kka2_1:2,P00552,0.963965,NO,42,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.907,-5.227,2.32,,1.044,T,B,0.64,-0.8,2.792,,71.59,HPO,-2.12433,0.295029,0.00679212,0.963965 beta-lactamase_G279S,beta-lactamase_279,TEM-1,beta-lactamase,P62593,0.963966,NO,279,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.038,-2.112,1.074,4.53882,,H,A,0.46,-0.97,3.066,,62.59,HOH,-1.36467,0.221079,0.0192826,0.963966 beta-lactamase_Q86C,beta-lactamase_86,TEM-1,beta-lactamase,P62593,0.963966,NO,86,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.4,-5.132,2.732,5.39897,0.696,S,A,0.12,2.38,2.105,,77.62,OPA,-1.61067,0.221079,0.00450027,0.963966 beta-lactamase_2500_H94N,beta-lactamase_2500_94,TEM-1,beta-lactamase_2500,P62593,0.963995,NO,94,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-2.5,-3.811,1.311,,0.776,,B,0.17,1.24,1.176,,77.62,HBH,-1.872,0.361275,0.00389226,0.963995 kka2_1:2_Q26T,kka2_1:2_26,Kka2,kka2_1:2,P00552,0.964003,NO,26,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.18,-3.677,1.497,,0.448,E,B,0.4,0.44,5.022,,92.05,HPP,-2.11167,0.295029,0.00708962,0.964003 beta-lactamase_39_K254W,beta-lactamase_39_254,TEM-1,beta-lactamase_39,P62593,0.964008,NO,254,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.0495842,0.00369,0.964008 PSD95pdz3_Q374K,PSD95pdz3_374,PSD95pdz3,PSD95pdz3,P31016,0.964018,NO,374,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-1.699,-2.689,0.99,5.38825,,,,,17.3289,,,,APH,-1.47,0.0758425,0.000372298,0.964018 beta-lactamase_39_H94N,beta-lactamase_39_94,TEM-1,beta-lactamase_39,P62593,0.96402,NO,94,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-2.5,-3.811,1.311,,0.776,,B,0.17,1.24,11.583,11.583,77.62,HBH,-1.872,0.0495842,0.00389226,0.96402 Pab1_E161S,Pab1_161,Pab1,Pab1,P04147,0.964029,NO,161,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.474,-3.052,1.578,,0.663,T,a,,1.34,,,,AAP,-1.59067,0.175299,0.00276141,0.964029 beta-lactamase_156_L146T,beta-lactamase_156_146,TEM-1,beta-lactamase_156,P62593,0.964039,NO,146,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.462,-3.533,2.071,,0.007,H,A,0.55,-0.56,1.578,,64.69,AHP,-1.656,0.111618,0.00474542,0.964039 beta-lactamase_39_L111M,beta-lactamase_39_111,TEM-1,beta-lactamase_39,P62593,0.964041,NO,111,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.76,-4.22,2.46,,0.328,T,A,0.55,0.93,4.334,,64.34,BHP,-1.884,0.0495842,0.00480671,0.964041 beta-lactamase_H110R,beta-lactamase_110,TEM-1,beta-lactamase,P62593,0.964042,NO,110,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-1.706,-2.008,0.302,5.52635,0.341,G,a,0.35,1.08,31.31,31.31,64.69,BBH,-1.73333,0.221079,0.00441499,0.964042 beta-lactamase_39_K254R,beta-lactamase_39_254,TEM-1,beta-lactamase_39,P62593,0.964057,NO,254,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.0495842,0.00369,0.964057 kka2_1:4_G10C,kka2_1:4_10,Kka2,kka2_1:4,P00552,0.964058,NO,10,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.921,-5.151,3.23,,,,,,,1.862,,71.59,HOP,-2.10733,0.168804,0.00289233,0.964058 beta-lactamase_625_K213A,beta-lactamase_625_213,TEM-1,beta-lactamase_625,P62593,0.964075,NO,213,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.81,-3.194,1.384,,0.67,,A,2.34,0.29,3.924,,67.83,ABH,-1.57767,0.213352,0.00610411,0.964075 beta-lactamase_156_L146Q,beta-lactamase_156_146,TEM-1,beta-lactamase_156,P62593,0.964076,NO,146,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.462,-4.29,2.828,,0.007,H,A,0.55,-0.56,1.578,,64.69,AHP,-1.656,0.111618,0.00474542,0.964076 beta-lactamase_625_L89H,beta-lactamase_625_89,TEM-1,beta-lactamase_625,P62593,0.96408,NO,89,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.096,-4.892,3.796,,0.168,T,A,0.55,0.63,1.599,,64.34,PHO,-1.75767,0.213352,0.00207068,0.96408 beta-lactamase_0_E195P,beta-lactamase_0_195,TEM-1,beta-lactamase_0,P62593,0.964082,NO,195,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.186,-2.83,0.644,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.0500837,0.00496565,0.964082 beta-lactamase_2500_L49F,beta-lactamase_2500_49,TEM-1,beta-lactamase_2500,P62593,0.964088,NO,49,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.897,-3.092,1.195,,0.131,T,A,0.55,0.04,6.681,,64.69,AHP,-1.99233,0.361275,0.00401477,0.964088 beta-lactamase_39_T139F,beta-lactamase_39_139,TEM-1,beta-lactamase_39,P62593,0.964109,NO,139,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.901,-4.292,2.391,,0.216,H,A,0.22,0.39,0.421,,77.62,PPH,-2.04667,0.0495842,0.00441837,0.964109 beta-lactamase_625_L160N,beta-lactamase_625_160,TEM-1,beta-lactamase_625,P62593,0.964109,NO,160,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.977,-4.165,3.188,,0.022,,B,0.55,-0.6,0.237,,44.41,BHA,-0.936,0.213352,0.00193775,0.964109 beta-lactamase_39_D231I,beta-lactamase_39_231,TEM-1,beta-lactamase_39,P62593,0.964127,NO,231,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.816,-4.036,3.22,,,E,B,0.75,-1.06,0.462,,65.38,HAB,-0.994,0.0495842,0.00107395,0.964127 Pab1_N132Q,Pab1_132,Pab1,Pab1,P04147,0.964127,NO,132,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-1.079,-3.491,2.412,,0.412,S,l,,0.9,,,,BPH,-1.067,0.175299,0.000347671,0.964127 Pab1_D160V,Pab1_160,Pab1,Pab1,P04147,0.964132,NO,160,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.985,-3.571,2.586,,0.396,B,B,,1.12,,,,PAA,-1.30133,0.175299,0.000311977,0.964132 beta-lactamase_39_M153H,beta-lactamase_39_153,TEM-1,beta-lactamase_39,P62593,0.964133,NO,153,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-3.193,-4.946,1.753,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.0495842,0.00509109,0.964133 beta-lactamase_0_L197F,beta-lactamase_0_197,TEM-1,beta-lactamase_0,P62593,0.964148,NO,197,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.853,-3.685,2.832,,0.007,S,B,0.55,0.33,1.087,,60.14,HHP,-1.833,0.0500837,0.00144602,0.964148 beta-lactamase_39_E175T,beta-lactamase_39_175,TEM-1,beta-lactamase_39,P62593,0.96415,NO,175,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.336,-3.551,1.215,,0.551,,A,1.04,1.05,3.676,,77.62,AAB,-1.31233,0.0495842,0.00482205,0.96415 beta-lactamase_D207C,beta-lactamase_207,TEM-1,beta-lactamase,P62593,0.964153,NO,207,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.064,-5.19,3.126,5.40404,0.409,H,A,0.23,0.12,1.975,,77.62,HAH,-1.77033,0.221079,0.00592942,0.964153 beta-lactamase_F22Y,beta-lactamase_22,TEM-1,beta-lactamase,P62593,0.964153,NO,22,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-2.676,-2.666,-0.01,,,,,,,1.616,,73.08,HHH,-2.03233,0.221079,0.00262842,0.964153 PSD95pdz3_A370Y,PSD95pdz3_370,PSD95pdz3,PSD95pdz3,P31016,0.964156,NO,370,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.307,-3.844,2.537,5.22304,,,,,17.284,,,,PHP,-1.57967,0.0758425,0.000429106,0.964156 beta-lactamase_39_P217R,beta-lactamase_39_217,TEM-1,beta-lactamase_39,P62593,0.964166,NO,217,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-2.062,-3.069,1.007,,0.496,I,A,0.52,-0.33,21.172,21.172,74.48,OOH,-1.64333,0.0495842,0.00463211,0.964166 beta-lactamase_2500_L55Y,beta-lactamase_2500_55,TEM-1,beta-lactamase_2500,P62593,0.96419,NO,55,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.86,-3.812,1.952,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.361275,0.00403741,0.96419 beta-lactamase_156_S122K,beta-lactamase_156_122,TEM-1,beta-lactamase_156,P62593,0.964199,NO,122,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.406,-3.55,1.144,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.111618,0.00497825,0.964199 beta-lactamase_0_G85H,beta-lactamase_0_85,TEM-1,beta-lactamase_0,P62593,0.964233,NO,85,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.011,-4.646,3.635,,0.805,T,l,0.29,1.7,2.25,,63.64,HOP,-1.68733,0.0500837,0.00252173,0.964233 beta-lactamase_2500_T107S,beta-lactamase_2500_107,TEM-1,beta-lactamase_2500,P62593,0.964234,NO,107,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.117,-1.871,0.754,,,G,A,0.22,-0.06,2.686,,67.83,HPA,-1.265,0.361275,0.00239347,0.964234 beta-lactamase_T267C,beta-lactamase_267,TEM-1,beta-lactamase,P62593,0.964241,NO,267,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.308,-5.019,2.711,5.28263,0.54,,B,0.69,-0.14,0.374,,73.78,HPH,-1.9,0.221079,0.0102128,0.964241 beta-lactamase_39_D161W,beta-lactamase_39_161,TEM-1,beta-lactamase_39,P62593,0.964246,NO,161,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.891,-5.546,4.655,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.0495842,0.000897697,0.964246 Pab1_D138P,Pab1_138,Pab1,Pab1,P04147,0.964246,NO,138,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.128,-3.525,2.397,,0.427,,B,,-0.03,,,,HAP,-1.13967,0.175299,0.000567877,0.964246 beta-lactamase_625_S104C,beta-lactamase_625_104,TEM-1,beta-lactamase_625,P62593,0.96425,NO,104,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.015,-2.945,1.93,,0.04,,b,0.27,0.57,1.76,,63.29,HPO,-1.05267,0.213352,0.00218083,0.96425 beta-lactamase_T126A,beta-lactamase_126,TEM-1,beta-lactamase,P62593,0.964266,NO,126,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.122,-2.955,1.833,4.82694,0.05,H,A,0.3,-0.05,1.14,,44.41,HPH,-1.60467,0.221079,0.00244552,0.964266 beta-lactamase_I125I,beta-lactamase_125,TEM-1,beta-lactamase,P62593,0.964277,NO,125,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.441,-1.441,,5.23481,,H,A,2.82,-0.7,2.301,,63.29,HHP,-1.248,0.221079,0.00383964,0.964277 Pab1_D144F,Pab1_144,Pab1,Pab1,P04147,0.964279,NO,144,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.189,-4.185,2.996,,0.616,H,A,,0.6,,,,HAP,-1.40567,0.175299,0.00121131,0.964279 gb1_T279M,gb1_279,gb1,gb1,P06654,0.964295,NO,279,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.32,-4.169,2.849,,,,,,,0.529,,35.71,HPH,-1.50067,0.177985,0.00421454,0.964295 beta-lactamase_R162H,beta-lactamase_162,TEM-1,beta-lactamase,P62593,0.964327,NO,162,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.016,-4.37,3.354,5.34456,0.124,S,B,0.68,-0.37,31.656,31.656,64.69,ABH,-1.25,0.221079,0.000561334,0.964327 beta-lactamase_T139R,beta-lactamase_139,TEM-1,beta-lactamase,P62593,0.964327,NO,139,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.901,-2.238,0.337,5.69095,0.216,H,A,0.3,0.39,2.256,,77.62,PPH,-2.04667,0.221079,0.00441837,0.964327 beta-lactamase_2500_K213V,beta-lactamase_2500_213,TEM-1,beta-lactamase_2500,P62593,0.96433,NO,213,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.81,-3.705,1.895,,0.67,,A,2.34,0.29,1.668,,67.83,ABH,-1.57767,0.361275,0.00610411,0.96433 beta-lactamase_156_D252Y,beta-lactamase_156_252,TEM-1,beta-lactamase_156,P62593,0.964332,NO,252,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.111618,0.00575769,0.964332 beta-lactamase_625_T126M,beta-lactamase_625_126,TEM-1,beta-lactamase_625,P62593,0.964336,NO,126,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.122,-4.659,3.537,,0.05,H,A,0.22,-0.05,0.817,,44.41,HPH,-1.60467,0.213352,0.00244552,0.964336 beta-lactamase_625_F64M,beta-lactamase_625_64,TEM-1,beta-lactamase_625,P62593,0.964358,NO,64,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-0.841,-4.255,3.414,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.213352,0.000947691,0.964358 beta-lactamase_39_T139S,beta-lactamase_39_139,TEM-1,beta-lactamase_39,P62593,0.964363,NO,139,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.901,-2.265,0.364,,0.216,H,A,0.22,0.39,0.421,,77.62,PPH,-2.04667,0.0495842,0.00441837,0.964363 beta-lactamase_2500_I206C,beta-lactamase_2500_206,TEM-1,beta-lactamase_2500,P62593,0.964375,NO,206,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-2.429,-4.969,2.54,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.361275,0.00528934,0.964375 WW_domain_Q200G,WW_domain_200,Yap65,WW_domain,P46937,0.964384,NO,200,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-1.599,-3.247,1.648,5.37476,,,,,,1.9,,70.04,HPA,-1.484,0.153962,0.00300397,0.964384 beta-lactamase_39_G216W,beta-lactamase_39_216,TEM-1,beta-lactamase_39,P62593,0.9644,NO,216,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.477,-5.45,3.973,,0.437,I,A,0.29,-0.58,0.834,,74.48,HOO,-1.68067,0.0495842,0.00639568,0.9644 beta-lactamase_0_V72Y,beta-lactamase_0_72,TEM-1,beta-lactamase_0,P62593,0.964406,NO,72,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.658,-4.055,2.397,,,H,A,0.44,-1.03,2.964,,65.73,BHH,-1.32167,0.0500837,0.00501194,0.964406 beta-lactamase_Q4A,beta-lactamase_4,TEM-1,beta-lactamase,P62593,0.96441,NO,4,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,,-2.985,0.421,,,,,,,,,,HPB,,0.221079,0.00316562,0.96441 beta-lactamase_39_M153K,beta-lactamase_39_153,TEM-1,beta-lactamase_39,P62593,0.964421,NO,153,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-3.193,-3.777,0.584,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.0495842,0.00509109,0.964421 Pab1_M189F,Pab1_189,Pab1,Pab1,P04147,0.964422,NO,189,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.406,-3.434,2.028,,0.631,E,b,,2.81,,,,OHH,-1.18,0.175299,0.000278756,0.964422 WW_domain_Q200Y,WW_domain_200,Yap65,WW_domain,P46937,0.964429,NO,200,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-1.599,-3.92,2.321,5.37476,,,,,,1.9,,70.04,HPA,-1.484,0.153962,0.00300397,0.964429 beta-lactamase_0_R41S,beta-lactamase_0_41,TEM-1,beta-lactamase_0,P62593,0.964434,NO,41,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-0.942,-2.526,1.584,,0.321,E,B,1.2,-0.07,2.68,,65.03,HBH,-1.30267,0.0500837,0.00123327,0.964434 beta-lactamase_2500_T126A,beta-lactamase_2500_126,TEM-1,beta-lactamase_2500,P62593,0.964453,NO,126,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.122,-2.955,1.833,,0.05,H,A,0.22,-0.05,0.817,,44.41,HPH,-1.60467,0.361275,0.00244552,0.964453 beta-lactamase_0_K109W,beta-lactamase_0_109,TEM-1,beta-lactamase_0,P62593,0.964457,NO,109,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.734,-5.518,3.784,,0.787,G,A,2.34,2.21,15.473,15.473,72.73,ABB,-1.63333,0.0500837,0.00462493,0.964457 PSD95pdz3_A370G,PSD95pdz3_370,PSD95pdz3,PSD95pdz3,P31016,0.964488,NO,370,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.307,-2.59,1.283,5.22304,,,,,17.284,,,,PHP,-1.57967,0.0758425,0.000429106,0.964488 beta-lactamase_156_V259S,beta-lactamase_156_259,TEM-1,beta-lactamase_156,P62593,0.964496,NO,259,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.111618,0.0070773,0.964496 beta-lactamase_156_D113N,beta-lactamase_156_113,TEM-1,beta-lactamase_156,P62593,0.964521,NO,113,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.829,-3.682,1.853,,0.665,T,A,0.75,0.91,2.973,,73.08,PAO,-1.703,0.111618,0.00474112,0.964521 beta-lactamase_2500_G39N,beta-lactamase_2500_39,TEM-1,beta-lactamase_2500,P62593,0.964523,NO,39,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.864,-2.55,0.686,,0.701,T,L,0.29,0.47,29.926,29.926,77.62,HOH,-1.53633,0.361275,0.00487611,0.964523 beta-lactamase_P217E,beta-lactamase_217,TEM-1,beta-lactamase,P62593,0.964529,NO,217,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-2.062,-2.651,0.589,5.19872,0.496,I,A,0.99,-0.33,0.431,,74.48,OOH,-1.64333,0.221079,0.00463211,0.964529 beta-lactamase_0_R118F,beta-lactamase_0_118,TEM-1,beta-lactamase_0,P62593,0.96453,NO,118,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.413,-4.338,1.925,,0.457,H,A,1.2,1.39,3.961,,77.62,HBA,-1.785,0.0500837,0.00538794,0.96453 beta-lactamase_39_N152F,beta-lactamase_39_152,TEM-1,beta-lactamase_39,P62593,0.964539,NO,152,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-2.757,-4.363,1.606,,0.863,H,A,0.61,0.92,4.038,,77.62,BPH,-2.97,0.0495842,0.00471429,0.964539 hsp90_N588F,hsp90_588,hsp90,hsp90,P02829,0.964551,NO,588,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-3.051,-3.22,0,4.61142,0.019,H,A,0.14,0.39,,,,HPH,-3.12167,0.368192,0.000222939,0.964551 kka2_1:8_G88N,kka2_1:8_88,Kka2,kka2_1:8,P00552,0.964555,NO,88,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.689,-2.869,1.18,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.100394,0.00685559,0.964555 kka2_1:8_G88N,kka2_1:8_88,Kka2,kka2_1:8,P00552,0.964555,NO,88,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.689,-2.869,1.18,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.100394,0.00685559,0.964555 beta-lactamase_0_G281I,beta-lactamase_0_281,TEM-1,beta-lactamase_0,P62593,0.964579,NO,281,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.0500837,0.0406482,0.964579 beta-lactamase_39_P105H,beta-lactamase_39_105,TEM-1,beta-lactamase_39,P62593,0.964579,NO,105,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.813,-4.678,3.865,,0.226,T,A,0.52,0.8,1.222,,63.29,POH,-1.01533,0.0495842,0.0011981,0.964579 beta-lactamase_2500_T147N,beta-lactamase_2500_147,TEM-1,beta-lactamase_2500,P62593,0.964587,NO,147,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.149,-2.415,1.266,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.361275,0.00226017,0.964587 beta-lactamase_0_R275W,beta-lactamase_0_275,TEM-1,beta-lactamase_0,P62593,0.964601,NO,275,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.0500837,0.0141984,0.964601 beta-lactamase_2500_L111H,beta-lactamase_2500_111,TEM-1,beta-lactamase_2500,P62593,0.964605,NO,111,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.76,-4.922,3.162,,0.328,T,A,0.55,0.93,1.966,,64.34,BHP,-1.884,0.361275,0.00480671,0.964605 beta-lactamase_0_L218Y,beta-lactamase_0_218,TEM-1,beta-lactamase_0,P62593,0.964614,NO,218,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.391,-4.087,2.696,,,I,b,0.55,-0.53,28.707,28.707,74.48,OHH,-1.58867,0.0500837,0.00618274,0.964614 kka2_1:4_D118R,kka2_1:4_118,Kka2,kka2_1:4,P00552,0.964645,NO,118,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.07,-3.951,1.881,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.168804,0.0067852,0.964645 beta-lactamase_625_S241N,beta-lactamase_625_241,TEM-1,beta-lactamase_625,P62593,0.964656,NO,241,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.213352,0.00452736,0.964656 beta-lactamase_156_E62T,beta-lactamase_156_62,TEM-1,beta-lactamase_156,P62593,0.964658,NO,62,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.193,-3.522,2.329,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.111618,0.00264802,0.964658 beta-lactamase_39_Y262I,beta-lactamase_39_262,TEM-1,beta-lactamase_39,P62593,0.964661,NO,262,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.0495842,0.00853516,0.964661 beta-lactamase_S254L,beta-lactamase_254,TEM-1,beta-lactamase,P62593,0.964662,NO,254,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.126,-3.603,1.477,5.49575,0.312,,a,0.25,-0.48,24.91,24.91,69.58,OPB,-2.215,0.221079,0.00369,0.964662 PSD95pdz3_R313I,PSD95pdz3_313,PSD95pdz3,PSD95pdz3,P31016,0.964667,NO,313,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.582,-3.692,2.11,6.63563,,,,,18.3955,,,,BBH,-1.59733,0.0758425,0.000840067,0.964667 beta-lactamase_625_V42F,beta-lactamase_625_42,TEM-1,beta-lactamase_625,P62593,0.964668,NO,42,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.564,-3.895,2.331,,0.017,E,B,0.44,-0.51,2.576,,63.99,BHO,-1.042,0.213352,0.00404515,0.964668 Pab1_K180H,Pab1_180,Pab1,Pab1,P04147,0.964669,NO,180,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.945,-4.415,2.47,,,,,,,,,,HBA,-1.575,0.175299,0.00295933,0.964669 beta-lactamase_2500_E46T,beta-lactamase_2500_46,TEM-1,beta-lactamase_2500,P62593,0.964687,NO,46,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.94,-3.517,1.577,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.361275,0.00427568,0.964687 beta-lactamase_0_A77W,beta-lactamase_0_77,TEM-1,beta-lactamase_0,P62593,0.9647,NO,77,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.234,-5.367,4.133,,0.039,H,A,0.46,-0.56,2.591,,64.34,OHH,-1.294,0.0500837,0.00282362,0.9647 beta-lactamase_156_G39C,beta-lactamase_156_39,TEM-1,beta-lactamase_156,P62593,0.964716,NO,39,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.864,-5.191,3.327,,0.701,T,L,0.29,0.47,1.454,,77.62,HOH,-1.53633,0.111618,0.00487611,0.964716 Pab1_A158S,Pab1_158,Pab1,Pab1,P04147,0.964742,NO,158,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.154,-2.934,1.78,,,,,,,1.197,,56.33,HHP,-1.40733,0.175299,0.000649733,0.964742 beta-lactamase_0_I277H,beta-lactamase_0_277,TEM-1,beta-lactamase_0,P62593,0.964761,NO,277,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.0500837,0.0169305,0.964761 beta-lactamase_156_L47G,beta-lactamase_156_47,TEM-1,beta-lactamase_156,P62593,0.964777,NO,47,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.876,-3.777,1.901,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.111618,0.00439844,0.964777 beta-lactamase_39_G85D,beta-lactamase_39_85,TEM-1,beta-lactamase_39,P62593,0.964783,NO,85,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.011,-2.383,1.372,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.0495842,0.00252173,0.964783 beta-lactamase_625_K213H,beta-lactamase_625_213,TEM-1,beta-lactamase_625,P62593,0.964783,NO,213,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.81,-4.552,2.742,,0.67,,A,2.34,0.29,3.924,,67.83,ABH,-1.57767,0.213352,0.00610411,0.964783 beta-lactamase_2500_K109W,beta-lactamase_2500_109,TEM-1,beta-lactamase_2500,P62593,0.964784,NO,109,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.734,-5.518,3.784,,0.787,G,A,2.34,2.21,0.998,,72.73,ABB,-1.63333,0.361275,0.00462493,0.964784 beta-lactamase_39_E56H,beta-lactamase_39_56,TEM-1,beta-lactamase_39,P62593,0.96481,NO,56,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.043,-4.467,2.424,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.0495842,0.00238534,0.96481 beta-lactamase_0_T193G,beta-lactamase_0_193,TEM-1,beta-lactamase_0,P62593,0.964817,NO,193,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.914,-3.548,1.634,,0.439,H,a,0.22,0.33,11.546,11.546,63.99,HPO,-1.52133,0.0500837,0.00482669,0.964817 Pab1_S147V,Pab1_147,Pab1,Pab1,P04147,0.964829,NO,147,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.267,-3.269,2.002,,0.336,H,A,,0.56,,,,HPH,-1.43033,0.175299,0.000610856,0.964829 beta-lactamase_0_L28R,beta-lactamase_0_28,TEM-1,beta-lactamase_0,P62593,0.964833,NO,28,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.579,-2.903,1.324,,0.277,H,A,0.55,-0.16,9.35,9.35,93.01,PHH,-2.11333,0.0500837,0.00359321,0.964833 beta-lactamase_0_T126N,beta-lactamase_0_126,TEM-1,beta-lactamase_0,P62593,0.964838,NO,126,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.122,-3.467,2.345,,0.05,H,A,0.22,-0.05,0.705,,44.41,HPH,-1.60467,0.0500837,0.00244552,0.964838 beta-lactamase_0_M184G,beta-lactamase_0_184,TEM-1,beta-lactamase_0,P62593,0.964854,NO,184,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.593,-3.601,2.008,,,H,A,0.55,-0.87,13.292,13.292,62.94,HHH,-1.41,0.0500837,0.00356019,0.964854 beta-lactamase_E62D,beta-lactamase_62,TEM-1,beta-lactamase,P62593,0.964854,NO,62,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.193,-2.088,0.895,5.93066,0.342,S,B,1.52,-0.3,3.139,,73.08,AAB,-1.417,0.221079,0.00264802,0.964854 beta-lactamase_L120L,beta-lactamase_120,TEM-1,beta-lactamase,P62593,0.964854,NO,120,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.044,-1.044,,5.11974,,H,A,1.3,-1.13,1.988,,64.69,AHO,-1.13633,0.221079,0.00143563,0.964854 beta-lactamase_R41N,beta-lactamase_41,TEM-1,beta-lactamase,P62593,0.964854,NO,41,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-0.942,-3.445,2.503,5.69185,0.321,E,B,0.91,-0.07,4.357,,65.03,HBH,-1.30267,0.221079,0.00123327,0.964854 kka2_1:2_R44L,kka2_1:2_44,Kka2,kka2_1:2,P00552,0.964864,NO,44,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.062,-2.371,0.309,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.295029,0.00745043,0.964864 beta-lactamase_39_A170E,beta-lactamase_39_170,TEM-1,beta-lactamase_39,P62593,0.964886,NO,170,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.237,-3.626,2.389,,0.126,,L,0.46,-0.35,3.7,,64.69,AHH,-1.63267,0.0495842,0.00431903,0.964886 PSD95pdz3_R368E,PSD95pdz3_368,PSD95pdz3,PSD95pdz3,P31016,0.964891,NO,368,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.582,-2.897,1.315,6.13355,,,,,18.1818,,,,HBP,-1.50033,0.0758425,0.000451517,0.964891 beta-lactamase_2500_E175N,beta-lactamase_2500_175,TEM-1,beta-lactamase_2500,P62593,0.964896,NO,175,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.336,-3.857,1.521,,0.551,,A,1.04,1.05,5.316,,77.62,AAB,-1.31233,0.361275,0.00482205,0.964896 kka2_1:2_A9W,kka2_1:2_9,Kka2,kka2_1:2,P00552,0.964897,NO,9,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.079,-5.293,3.214,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.295029,0.00273264,0.964897 beta-lactamase_L191I,beta-lactamase_191,TEM-1,beta-lactamase,P62593,0.964904,NO,191,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.087,-3.028,1.941,5.72226,,H,A,1.07,0.09,1.23,,63.29,BHH,-1.445,0.221079,0.00263549,0.964904 beta-lactamase_2500_L146F,beta-lactamase_2500_146,TEM-1,beta-lactamase_2500,P62593,0.964905,NO,146,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.462,-2.298,0.836,,0.007,H,A,0.55,-0.56,1.578,,64.69,AHP,-1.656,0.361275,0.00474542,0.964905 beta-lactamase_39_L218Q,beta-lactamase_39_218,TEM-1,beta-lactamase_39,P62593,0.96491,NO,218,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.391,-3.953,2.562,,,I,b,0.55,-0.53,2.038,,74.48,OHH,-1.58867,0.0495842,0.00618274,0.96491 beta-lactamase_39_M115G,beta-lactamase_39_115,TEM-1,beta-lactamase_39,P62593,0.964939,NO,115,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.389,-3.632,2.243,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.0495842,0.0034337,0.964939 beta-lactamase_K53F,beta-lactamase_53,TEM-1,beta-lactamase,P62593,0.964953,NO,53,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-2.313,-4.249,1.936,5.93654,0.589,,B,1.82,1.15,19.72,19.72,77.62,OBH,-2.1,0.221079,0.00383383,0.964953 beta-lactamase_0_G253F,beta-lactamase_0_253,TEM-1,beta-lactamase_0,P62593,0.96497,NO,253,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.0500837,0.00786358,0.96497 beta-lactamase_2500_V101T,beta-lactamase_2500_101,TEM-1,beta-lactamase_2500,P62593,0.96497,NO,101,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.295,-3.446,2.151,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.361275,0.00374492,0.96497 kka2_1:8_G201K,kka2_1:8_201,Kka2,kka2_1:8,P00552,0.964984,NO,201,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.56,-2.796,1.236,,0.149,T,l,0.75,-0.57,2.152,,52.65,POB,-1.92233,0.100394,0.00820117,0.964984 kka2_1:8_G201K,kka2_1:8_201,Kka2,kka2_1:8,P00552,0.964984,NO,201,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.56,-2.796,1.236,,0.149,T,l,0.75,-0.57,2.152,,52.65,POB,-1.92233,0.100394,0.00820117,0.964984 beta-lactamase_39_V117M,beta-lactamase_39_117,TEM-1,beta-lactamase_39,P62593,0.965003,NO,117,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.53,-3.063,1.533,,,H,A,0.44,-0.34,1.182,,65.03,PHB,-1.741,0.0495842,0.00467906,0.965003 beta-lactamase_39_K254T,beta-lactamase_39_254,TEM-1,beta-lactamase_39,P62593,0.965013,NO,254,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.0495842,0.00369,0.965013 beta-lactamase_156_H151F,beta-lactamase_156_151,TEM-1,beta-lactamase_156,P62593,0.965015,NO,151,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-2.96,-4.308,1.348,,0.594,H,A,0.17,0.1,1.401,,77.62,HBP,-2.34767,0.111618,0.00216946,0.965015 beta-lactamase_0_Q86P,beta-lactamase_0_86,TEM-1,beta-lactamase_0,P62593,0.965018,NO,86,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.4,-3.985,1.585,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.0500837,0.00450027,0.965018 beta-lactamase_156_R63F,beta-lactamase_156_63,TEM-1,beta-lactamase_156,P62593,0.965038,NO,63,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-0.943,-4.214,3.271,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.111618,0.00126938,0.965038 beta-lactamase_H156F,beta-lactamase_156,TEM-1,beta-lactamase,P62593,0.965047,NO,156,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-3.156,-4.428,1.272,6.00284,0.753,S,A,0.72,-0.6,6.456,6.456,77.62,ABH,-1.932,0.221079,0.00468596,0.965047 beta-lactamase_2500_D113M,beta-lactamase_2500_113,TEM-1,beta-lactamase_2500,P62593,0.965051,NO,113,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.829,-4.826,2.997,,0.665,T,A,0.75,0.91,21.104,21.104,73.08,PAO,-1.703,0.361275,0.00474112,0.965051 PSD95pdz3_L323C,PSD95pdz3_323,PSD95pdz3,PSD95pdz3,P31016,0.965054,NO,323,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.347,-4.319,2.972,5.12397,,,,,13.8825,,,,OHO,-1.121,0.0758425,0.00104644,0.965054 beta-lactamase_39_L150Q,beta-lactamase_39_150,TEM-1,beta-lactamase_39,P62593,0.965081,NO,150,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.326,-4.106,2.78,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.0495842,0.00463171,0.965081 beta-lactamase_S80I,beta-lactamase_80,TEM-1,beta-lactamase,P62593,0.965093,NO,80,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.029,-3.787,1.758,5.23748,0.192,H,A,0.25,0.46,2.256,,77.62,HPB,-1.44567,0.221079,0.00565569,0.965093 gb1_Q258C,gb1_258,gb1,gb1,P06654,0.965096,NO,258,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.095,-4.82,2.725,,,,,,,0.86,,37.28,BPH,-1.88333,0.177985,0.00437595,0.965096 beta-lactamase_2500_R159Q,beta-lactamase_2500_159,TEM-1,beta-lactamase_2500,P62593,0.965108,NO,159,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-0.94,-3.498,2.558,,0.316,,B,1.2,-0.55,2.341,,64.34,PBH,-1.011,0.361275,0.00108472,0.965108 beta-lactamase_39_L248Q,beta-lactamase_39_248,TEM-1,beta-lactamase_39,P62593,0.965121,NO,248,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.0495842,0.00428493,0.965121 beta-lactamase_2500_M180C,beta-lactamase_2500_180,TEM-1,beta-lactamase_2500,P62593,0.965123,NO,180,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-2.795,-4.786,1.991,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.361275,0.00552048,0.965123 beta-lactamase_39_M270F,beta-lactamase_39_270,TEM-1,beta-lactamase_39,P62593,0.965163,NO,270,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.0495842,0.00767762,0.965163 beta-lactamase_39_D161F,beta-lactamase_39_161,TEM-1,beta-lactamase_39,P62593,0.965165,NO,161,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.891,-4.316,3.425,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.0495842,0.000897697,0.965165 kka2_1:2_R173V,kka2_1:2_173,Kka2,kka2_1:2,P00552,0.965168,NO,173,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.407,-3.707,1.3,,0.308,H,A,0.16,-0.13,15.389,15.389,65.53,HBH,-1.70533,0.295029,0.00784999,0.965168 beta-lactamase_156_D48M,beta-lactamase_156_48,TEM-1,beta-lactamase_156,P62593,0.965179,NO,48,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.101,-4.896,3.795,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.111618,0.0027273,0.965179 beta-lactamase_2500_T139G,beta-lactamase_2500_139,TEM-1,beta-lactamase_2500,P62593,0.965184,NO,139,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.901,-3.413,1.512,,0.216,H,A,0.22,0.39,2.256,,77.62,PPH,-2.04667,0.361275,0.00441837,0.965184 beta-lactamase_39_V214P,beta-lactamase_39_214,TEM-1,beta-lactamase_39,P62593,0.965205,NO,214,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.299,-3.919,2.62,,0.375,S,A,0.44,-0.44,18.838,18.838,74.48,BHH,-1.53733,0.0495842,0.00628442,0.965205 PSD95pdz3_N369P,PSD95pdz3_369,PSD95pdz3,PSD95pdz3,P31016,0.965205,NO,369,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-1.572,-3.56,1.988,5.91569,,,,,24.1262,0.44,,87.71,BPH,-1.487,0.0758425,0.000608412,0.965205 beta-lactamase_625_V82E,beta-lactamase_625_82,TEM-1,beta-lactamase_625,P62593,0.965209,NO,82,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.325,-3.751,2.426,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.213352,0.00397046,0.965209 Pab1_D184F,Pab1_184,Pab1,Pab1,P04147,0.965223,NO,184,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.5,-4.18,2.68,,,,,,,,,,HAH,-1.50133,0.175299,0.0011931,0.965223 beta-lactamase_G216M,beta-lactamase_216,TEM-1,beta-lactamase,P62593,0.965224,NO,216,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.477,-4.925,3.448,4.91694,0.437,I,A,0.23,-0.58,1.718,,74.48,HOO,-1.68067,0.221079,0.00639568,0.965224 beta-lactamase_M153N,beta-lactamase_153,TEM-1,beta-lactamase,P62593,0.965224,NO,153,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-3.193,-3.994,0.801,5.46509,0.14,T,A,1.07,-0.11,2.061,,77.62,PHO,-2.25767,0.221079,0.00509109,0.965224 beta-lactamase_R7K,beta-lactamase_7,TEM-1,beta-lactamase,P62593,0.965224,NO,7,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.683,-2.353,0.67,,,,,,,2.44,,67.13,HBH,-1.96267,0.221079,0.00211375,0.965224 beta-lactamase_156_S51I,beta-lactamase_156_51,TEM-1,beta-lactamase_156,P62593,0.965226,NO,51,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.526,-3.925,2.399,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.111618,0.00504821,0.965226 beta-lactamase_0_A215R,beta-lactamase_0_215,TEM-1,beta-lactamase_0,P62593,0.965234,NO,215,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.503,-3.862,2.359,,,,a,0.46,-0.93,0.494,,74.48,HHO,-1.42633,0.0500837,0.00544007,0.965234 WW_domain_I193G,WW_domain_193,Yap65,WW_domain,P46937,0.965236,NO,193,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.993,-3.437,1.444,6.15906,,,,,,1.833,,83.33,BHA,-1.756,0.153962,0.00587613,0.965236 beta-lactamase_39_A34I,beta-lactamase_39_34,TEM-1,beta-lactamase_39,P62593,0.965238,NO,34,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.059,-2.06,0.001,,,H,A,0.46,-0.54,13.292,13.292,73.78,AHA,-1.74967,0.0495842,0.00407913,0.965238 beta-lactamase_39_A225P,beta-lactamase_39_225,TEM-1,beta-lactamase_39,P62593,0.965239,NO,225,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.845,-3.112,1.267,,1,T,B,0.46,-0.38,9.874,9.874,74.48,OHO,-1.39967,0.0495842,0.00465057,0.965239 beta-lactamase_39_V101L,beta-lactamase_39_101,TEM-1,beta-lactamase_39,P62593,0.965255,NO,101,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.295,-2.095,0.8,,0.342,,B,0.44,0,2.96,,73.08,HHA,-1.54367,0.0495842,0.00374492,0.965255 beta-lactamase_39_G114L,beta-lactamase_39_114,TEM-1,beta-lactamase_39,P62593,0.965291,NO,114,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.094,-3.637,2.543,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.0495842,0.00224919,0.965291 beta-lactamase_0_E210K,beta-lactamase_0_210,TEM-1,beta-lactamase_0,P62593,0.965305,NO,210,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.319,-2.868,0.549,,0.476,H,A,1.04,0.75,3.618,,77.62,HAH,-1.88567,0.0500837,0.00663582,0.965305 kka2_1:8_D62A,kka2_1:8_62,Kka2,kka2_1:8,P00552,0.965308,NO,62,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.591,-2.125,0.534,,0.262,H,A,0.29,0.08,5.58,,64.39,PAA,-1.77833,0.100394,0.00744243,0.965308 kka2_1:8_D62A,kka2_1:8_62,Kka2,kka2_1:8,P00552,0.965308,NO,62,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.591,-2.125,0.534,,0.262,H,A,0.29,0.08,5.58,,64.39,PAA,-1.77833,0.100394,0.00744243,0.965308 beta-lactamase_156_R41W,beta-lactamase_156_41,TEM-1,beta-lactamase_156,P62593,0.965319,NO,41,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-0.942,-5.348,4.406,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.111618,0.00123327,0.965319 beta-lactamase_39_I245G,beta-lactamase_39_245,TEM-1,beta-lactamase_39,P62593,0.965327,NO,245,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.0495842,0.00391032,0.965327 beta-lactamase_2500_T263A,beta-lactamase_2500_263,TEM-1,beta-lactamase_2500,P62593,0.965339,NO,263,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.361275,0.0110582,0.965339 beta-lactamase_625_E102H,beta-lactamase_625_102,TEM-1,beta-lactamase_625,P62593,0.965363,NO,102,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.118,-3.309,1.191,,0.722,S,B,1.04,1.82,1.336,,73.08,HAH,-1.581,0.213352,0.00486633,0.965363 beta-lactamase_2500_M270F,beta-lactamase_2500_270,TEM-1,beta-lactamase_2500,P62593,0.96537,NO,270,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.723,,,,0.422,H,A,1.59,1.15,2.029,,64.34,PHA,-1.70933,0.361275,0.00767762,0.96537 Pab1_V171A,Pab1_171,Pab1,Pab1,P04147,0.965374,NO,171,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.113,-2.67,1.557,,0.008,E,b,0.23,-0.34,,,,HHB,-1.19733,0.175299,0.000298662,0.965374 beta-lactamase_625_P105F,beta-lactamase_625_105,TEM-1,beta-lactamase_625,P62593,0.965378,NO,105,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.813,-4.48,3.667,,0.226,T,A,0.52,0.8,1.154,,63.29,POH,-1.01533,0.213352,0.0011981,0.965378 WW_domain_E178T,WW_domain_178,Yap65,WW_domain,P46937,0.965382,NO,178,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.158,-3.198,2.04,5.22323,,,,,,,,,HAH,-1.299,0.153962,0.0016738,0.965382 beta-lactamase_625_R239N,beta-lactamase_625_239,TEM-1,beta-lactamase_625,P62593,0.965387,NO,239,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.213352,0.00213852,0.965387 beta-lactamase_E277Q,beta-lactamase_277,TEM-1,beta-lactamase,P62593,0.965387,NO,277,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.869,-3.833,1.964,5.51786,0.545,H,A,0.52,-0.01,2.022,,77.62,HAH,-1.45367,0.221079,0.0169305,0.965387 beta-lactamase_39_N152E,beta-lactamase_39_152,TEM-1,beta-lactamase_39,P62593,0.965388,NO,152,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-2.757,-2.679,-0.078,,0.863,H,A,0.61,0.92,4.038,,77.62,BPH,-2.97,0.0495842,0.00471429,0.965388 beta-lactamase_39_D83K,beta-lactamase_39_83,TEM-1,beta-lactamase_39,P62593,0.96539,NO,83,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.066,-3.429,2.363,,0.354,H,A,0.75,0.22,0.752,,48.95,HAH,-1.34733,0.0495842,0.00205968,0.96539 kka2_1:8_L241R,kka2_1:8_241,Kka2,kka2_1:8,P00552,0.965435,NO,241,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.158,-4.121,2.963,,0.08,H,A,1.59,-0.82,1.136,,63.26,HHH,-1.58533,0.100394,0.0117299,0.965435 kka2_1:8_L241R,kka2_1:8_241,Kka2,kka2_1:8,P00552,0.965435,NO,241,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.158,-4.121,2.963,,0.08,H,A,1.59,-0.82,1.136,,63.26,HHH,-1.58533,0.100394,0.0117299,0.965435 beta-lactamase_39_V42W,beta-lactamase_39_42,TEM-1,beta-lactamase_39,P62593,0.965436,NO,42,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.564,-5.336,3.772,,0.017,E,B,0.44,-0.51,1.86,,63.99,BHO,-1.042,0.0495842,0.00404515,0.965436 beta-lactamase_0_W163E,beta-lactamase_0_163,TEM-1,beta-lactamase_0,P62593,0.965465,NO,163,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-1.843,-3.693,1.85,,0.467,,B,0.47,-0.5,13.843,13.843,63.99,BHA,-1.269,0.0500837,0.00418955,0.965465 beta-lactamase_0_G226P,beta-lactamase_0_226,TEM-1,beta-lactamase_0,P62593,0.965468,NO,226,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.461,-3.96,2.499,,0.701,T,l,0.29,-0.25,23.034,23.034,74.48,HOH,-1.42933,0.0500837,0.00665294,0.965468 beta-lactamase_156_A222M,beta-lactamase_156_222,TEM-1,beta-lactamase_156,P62593,0.965477,NO,222,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.103,-4.656,2.553,,0.233,H,A,0.46,-0.25,2.461,,77.62,PHH,-1.63733,0.111618,0.00466094,0.965477 hsp90_E590A,hsp90_590,hsp90,hsp90,P02829,0.965483,NO,590,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.818,-2.456,0,4.65049,0.021,H,A,,0.03,,,,HAO,-3.338,0.368192,0.000222939,0.965483 beta-lactamase_39_L223N,beta-lactamase_39_223,TEM-1,beta-lactamase_39,P62593,0.96549,NO,223,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.055,-4.1,3.045,,0.27,,B,0.55,0.09,1.511,,74.48,HHO,-1.35033,0.0495842,0.00372793,0.96549 WW_domain_K181R,WW_domain_181,Yap65,WW_domain,P46937,0.965496,NO,181,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.35,-3.087,1.737,5.0864,,,,,,0.176,,15.87,HBP,-1.247,0.153962,0.0033022,0.965496 WW_domain_T196L,WW_domain_196,Yap65,WW_domain,P46937,0.965498,NO,196,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.782,-3.08,1.298,5.5744,,,,,,5.836,,70.04,PPP,-1.732,0.153962,0.00421377,0.965498 E1_Ubiquitin_K48H,E1_Ubiquitin_48,Uba1,E1_Ubiquitin,P0CG63,0.965517,NO,48,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.219,-4.266,3.047,,0.132,E,B,,-0.28,,,,OBO,-1.109,0.18783,0.00100363,0.965517 beta-lactamase_R238W,beta-lactamase_238,TEM-1,beta-lactamase,P62593,0.965537,NO,238,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.002,-5.062,3.06,5.87663,0.564,T,L,0.45,1.09,4.195,,72.73,ABO,-1.62633,0.221079,0.00743256,0.965537 beta-lactamase_X287G,beta-lactamase_287,TEM-1,beta-lactamase,P62593,0.965537,NO,287,X,G,XG,Stop,Special,5.71,3.29388,-2.41612,,132.5,75,-57,141.9,60.1,-81.8,,,,,,,,,,,,,HXO,-1.111,0.221079,,0.965537 beta-lactamase_156_T131W,beta-lactamase_156_131,TEM-1,beta-lactamase_156,P62593,0.965542,NO,131,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.328,-5.315,3.987,,,H,A,0.22,-0.69,2.031,,67.48,PPH,-1.00867,0.111618,0.00345886,0.965542 Pab1_D144G,Pab1_144,Pab1,Pab1,P04147,0.965545,NO,144,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.189,-3.094,1.905,,0.616,H,A,,0.6,,,,HAP,-1.40567,0.175299,0.00121131,0.965545 beta-lactamase_0_W288N,beta-lactamase_0_288,TEM-1,beta-lactamase_0,P62593,0.965556,NO,288,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,,,,,,,,,,,,,BHO,,0.0500837,,0.965556 beta-lactamase_625_T131F,beta-lactamase_625_131,TEM-1,beta-lactamase_625,P62593,0.965563,NO,131,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.328,-4.204,2.876,,,H,A,0.22,-0.69,2.031,,67.48,PPH,-1.00867,0.213352,0.00345886,0.965563 beta-lactamase_156_K254Y,beta-lactamase_156_254,TEM-1,beta-lactamase_156,P62593,0.965564,NO,254,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.111618,0.00369,0.965564 beta-lactamase_2500_A200Y,beta-lactamase_2500_200,TEM-1,beta-lactamase_2500,P62593,0.965596,NO,200,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.878,-4.399,2.521,,0.757,H,A,0.46,-0.19,0.436,,77.62,HHP,-2.001,0.361275,0.0060056,0.965596 beta-lactamase_0_N274F,beta-lactamase_0_274,TEM-1,beta-lactamase_0,P62593,0.965598,NO,274,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.0500837,0.0110418,0.965598 beta-lactamase_39_D161R,beta-lactamase_39_161,TEM-1,beta-lactamase_39,P62593,0.965618,NO,161,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.891,-3.902,3.011,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.0495842,0.000897697,0.965618 beta-lactamase_0_G249E,beta-lactamase_0_249,TEM-1,beta-lactamase_0,P62593,0.965642,NO,249,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.0500837,0.00220169,0.965642 beta-lactamase_K213K,beta-lactamase_213,TEM-1,beta-lactamase,P62593,0.965643,NO,213,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.81,-1.81,,5.63167,0.67,,A,1.59,0.29,3.924,,67.83,ABH,-1.57767,0.221079,0.00610411,0.965643 Pab1_A141L,Pab1_141,Pab1,Pab1,P04147,0.965645,NO,141,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.461,-3.099,1.638,,0.34,H,A,0.52,-0.27,2.15,,79.03,BHH,-1.19433,0.175299,0.00165974,0.965645 beta-lactamase_39_D161A,beta-lactamase_39_161,TEM-1,beta-lactamase_39,P62593,0.965647,NO,161,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.891,-3.235,2.344,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.0495842,0.000897697,0.965647 beta-lactamase_39_L120H,beta-lactamase_39_120,TEM-1,beta-lactamase_39,P62593,0.965659,NO,120,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.044,-3.066,2.022,,,H,A,0.55,-1.13,22.254,22.254,64.69,AHO,-1.13633,0.0495842,0.00143563,0.965659 kka2_1:2_A172V,kka2_1:2_172,Kka2,kka2_1:2,P00552,0.965661,NO,172,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.757,-2.683,0.926,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.295029,0.0079265,0.965661 beta-lactamase_2500_V82A,beta-lactamase_2500_82,TEM-1,beta-lactamase_2500,P62593,0.965672,NO,82,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.325,-2.13,0.805,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.361275,0.00397046,0.965672 beta-lactamase_E277G,beta-lactamase_277,TEM-1,beta-lactamase,P62593,0.965677,NO,277,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.869,-1.848,-0.021,5.51786,0.545,H,A,0.52,-0.01,2.022,,77.62,HAH,-1.45367,0.221079,0.0169305,0.965677 beta-lactamase_S96I,beta-lactamase_96,TEM-1,beta-lactamase,P62593,0.965677,NO,96,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.27,-3.225,0.955,5.29889,0.368,,b,0.25,0.39,32.348,32.348,73.78,HPP,-2.019,0.221079,0.00551835,0.965677 beta-lactamase_625_R176D,beta-lactamase_625_176,TEM-1,beta-lactamase_625,P62593,0.965689,NO,176,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-0.863,-3.694,2.831,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.213352,0.00105554,0.965689 beta-lactamase_156_I206N,beta-lactamase_156_206,TEM-1,beta-lactamase_156,P62593,0.965695,NO,206,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-2.429,-3.933,1.504,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.111618,0.00528934,0.965695 PSD95pdz3_N363Y,PSD95pdz3_363,PSD95pdz3,PSD95pdz3,P31016,0.965702,NO,363,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-1.41,-3.844,2.434,5.23349,,,,,20.7037,,,,HPO,-1.29433,0.0758425,0.000524014,0.965702 beta-lactamase_39_D36T,beta-lactamase_39_36,TEM-1,beta-lactamase_39,P62593,0.965704,NO,36,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.732,-2.57,-0.162,,0.555,H,A,0.75,1.17,13.689,13.689,77.62,AAP,-1.91167,0.0495842,0.00476483,0.965704 kka2_1:8_G201M,kka2_1:8_201,Kka2,kka2_1:8,P00552,0.965712,NO,201,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.56,-4.972,3.412,,0.149,T,l,0.75,-0.57,2.152,,52.65,POB,-1.92233,0.100394,0.00820117,0.965712 kka2_1:8_G201M,kka2_1:8_201,Kka2,kka2_1:8,P00552,0.965712,NO,201,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.56,-4.972,3.412,,0.149,T,l,0.75,-0.57,2.152,,52.65,POB,-1.92233,0.100394,0.00820117,0.965712 beta-lactamase_0_F64I,beta-lactamase_0_64,TEM-1,beta-lactamase_0,P62593,0.965717,NO,64,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-0.841,-3.335,2.494,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.0500837,0.000947691,0.965717 beta-lactamase_39_G249C,beta-lactamase_39_249,TEM-1,beta-lactamase_39,P62593,0.965722,NO,249,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.312,,,,0.256,S,B,0.23,0.04,30.841,30.841,72.73,HOO,-1.81367,0.0495842,0.00220169,0.965722 PSD95pdz3_A347C,PSD95pdz3_347,PSD95pdz3,PSD95pdz3,P31016,0.965725,NO,347,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.307,-4.094,2.787,4.89689,,,,,15.176,,,,OHA,-1.269,0.0758425,0.00074525,0.965725 Pab1_E176Q,Pab1_176,Pab1,Pab1,P04147,0.965729,NO,176,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.003,-3.686,1.683,,,,,,,,,,AAO,-2.09933,0.175299,0.00264426,0.965729 beta-lactamase_H285Q,beta-lactamase_285,TEM-1,beta-lactamase,P62593,0.96573,NO,285,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-1.845,-2.669,0.824,5.64289,0.312,T,a,0.35,0.64,1.401,,72.73,BBH,-1.64567,0.221079,0.101555,0.96573 beta-lactamase_2500_I206F,beta-lactamase_2500_206,TEM-1,beta-lactamase_2500,P62593,0.965758,NO,206,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-2.429,-4.165,1.736,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.361275,0.00528934,0.965758 beta-lactamase_2500_E175C,beta-lactamase_2500_175,TEM-1,beta-lactamase_2500,P62593,0.965761,NO,175,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.336,-5.076,2.74,,0.551,,A,1.04,1.05,5.316,,77.62,AAB,-1.31233,0.361275,0.00482205,0.965761 kka2_1:8_V75R,kka2_1:8_75,Kka2,kka2_1:8,P00552,0.965764,NO,75,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-2.06,-4.101,2.041,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.100394,0.00693733,0.965764 kka2_1:8_V75R,kka2_1:8_75,Kka2,kka2_1:8,P00552,0.965764,NO,75,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-2.06,-4.101,2.041,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.100394,0.00693733,0.965764 Pab1_G177P,Pab1_177,Pab1,Pab1,P04147,0.965764,NO,177,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-2.24,-3.712,1.472,,,,,,,,,,AOH,-1.94067,0.175299,0.00170727,0.965764 beta-lactamase_39_V101P,beta-lactamase_39_101,TEM-1,beta-lactamase_39,P62593,0.965765,NO,101,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.295,-4.04,2.745,,0.342,,B,0.44,0,2.96,,73.08,HHA,-1.54367,0.0495842,0.00374492,0.965765 kka2_1:1_D52T,kka2_1:1_52,Kka2,kka2_1:1,P00552,0.965765,NO,52,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.271,-3.473,1.202,,0.22,E,B,0.75,0.8,2.64,,71.59,PAH,-2.38367,0.520039,0.00175694,0.965765 beta-lactamase_39_T27W,beta-lactamase_39_27,TEM-1,beta-lactamase_39,P62593,0.965769,NO,27,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.905,-5.314,3.409,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.0495842,0.00306559,0.965769 beta-lactamase_39_T178M,beta-lactamase_39_178,TEM-1,beta-lactamase_39,P62593,0.965772,NO,178,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-0.791,-4.48,3.689,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.0495842,0.000684366,0.965772 beta-lactamase_0_Q204A,beta-lactamase_0_204,TEM-1,beta-lactamase_0,P62593,0.96578,NO,204,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-1.382,-2.589,1.207,,0.204,H,A,0.64,0.09,2.646,,66.08,PPH,-1.49067,0.0500837,0.00364106,0.96578 beta-lactamase_L10C,beta-lactamase_10,TEM-1,beta-lactamase,P62593,0.965806,NO,10,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.623,-4.703,3.08,,,,,,,2.467,,65.38,HHH,-1.83833,0.221079,0.00296968,0.965806 beta-lactamase_39_Q97I,beta-lactamase_39_97,TEM-1,beta-lactamase_39,P62593,0.965815,NO,97,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.072,-4.072,2,,0.823,G,A,0.64,2.42,4.457,,77.62,PPP,-2.43833,0.0495842,0.0045116,0.965815 beta-lactamase_2500_Q204R,beta-lactamase_2500_204,TEM-1,beta-lactamase_2500,P62593,0.965817,NO,204,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-1.382,-2.322,0.94,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.361275,0.00364106,0.965817 beta-lactamase_156_D48N,beta-lactamase_156_48,TEM-1,beta-lactamase_156,P62593,0.965851,NO,48,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.101,-3.389,2.288,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.111618,0.0027273,0.965851 kka2_1:8_G55F,kka2_1:8_55,Kka2,kka2_1:8,P00552,0.965855,NO,55,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.625,-3.32,1.695,,0.517,S,b,0.29,1.19,8.881,,63.64,POH,-2.05967,0.100394,0.00667877,0.965855 kka2_1:8_G55F,kka2_1:8_55,Kka2,kka2_1:8,P00552,0.965855,NO,55,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.625,-3.32,1.695,,0.517,S,b,0.29,1.19,8.881,,63.64,POH,-2.05967,0.100394,0.00667877,0.965855 beta-lactamase_39_M180E,beta-lactamase_39_180,TEM-1,beta-lactamase_39,P62593,0.965872,NO,180,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-2.795,-3.532,0.737,,0.242,,B,0.55,-0.94,3.579,,77.62,PHO,-1.56433,0.0495842,0.00552048,0.965872 beta-lactamase_39_T139N,beta-lactamase_39_139,TEM-1,beta-lactamase_39,P62593,0.965877,NO,139,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.901,-3.686,1.785,,0.216,H,A,0.22,0.39,0.421,,77.62,PPH,-2.04667,0.0495842,0.00441837,0.965877 kka2_1:4_R89C,kka2_1:4_89,Kka2,kka2_1:4,P00552,0.965885,NO,89,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.548,-5.235,3.687,,0.209,E,B,1.2,1.41,4.412,,64.39,OBA,-1.89867,0.168804,0.00524373,0.965885 beta-lactamase_2500_D271R,beta-lactamase_2500_271,TEM-1,beta-lactamase_2500,P62593,0.96589,NO,271,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.249,-3.747,2.498,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.361275,0.00752082,0.96589 beta-lactamase_N152V,beta-lactamase_152,TEM-1,beta-lactamase,P62593,0.965926,NO,152,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-2.757,-3.616,0.859,5.98571,0.863,H,A,0.09,0.92,2.061,,77.62,BPH,-2.97,0.221079,0.00471429,0.965926 beta-lactamase_39_Y44G,beta-lactamase_39_44,TEM-1,beta-lactamase_39,P62593,0.965945,NO,44,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-2.547,-3.687,1.14,,,E,B,0.21,-0.45,2.683,,73.78,OHH,-1.86267,0.0495842,0.00426364,0.965945 beta-lactamase_39_D113S,beta-lactamase_39_113,TEM-1,beta-lactamase_39,P62593,0.965949,NO,113,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.829,-2.84,1.011,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.0495842,0.00474112,0.965949 beta-lactamase_39_Y103P,beta-lactamase_39_103,TEM-1,beta-lactamase_39,P62593,0.965961,NO,103,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-1.33,-4.138,2.808,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.0495842,0.00443048,0.965961 kka2_1:8_A34T,kka2_1:8_34,Kka2,kka2_1:8,P00552,0.965983,NO,34,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.928,-3.197,2.269,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.100394,0.00343484,0.965983 kka2_1:8_A34T,kka2_1:8_34,Kka2,kka2_1:8,P00552,0.965983,NO,34,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.928,-3.197,2.269,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.100394,0.00343484,0.965983 beta-lactamase_0_R91A,beta-lactamase_0_91,TEM-1,beta-lactamase_0,P62593,0.965992,NO,91,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.392,-2.55,1.158,,0.444,,B,1.2,0.96,4.557,,50.35,OBB,-1.73367,0.0500837,0.00380226,0.965992 beta-lactamase_2500_Q276F,beta-lactamase_2500_276,TEM-1,beta-lactamase_2500,P62593,0.966,NO,276,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.361275,0.0191712,0.966 beta-lactamase_625_L197H,beta-lactamase_625_197,TEM-1,beta-lactamase_625,P62593,0.966001,NO,197,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.853,-4.903,4.05,,0.007,S,B,0.55,0.33,1.756,,60.14,HHP,-1.833,0.213352,0.00144602,0.966001 beta-lactamase_0_S201T,beta-lactamase_0_201,TEM-1,beta-lactamase_0,P62593,0.966007,NO,201,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.183,-3.198,2.015,,0.064,H,A,0.27,-0.07,3.54,,64.69,HPB,-1.451,0.0500837,0.00198815,0.966007 beta-lactamase_39_Y103L,beta-lactamase_39_103,TEM-1,beta-lactamase_39,P62593,0.966011,NO,103,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-1.33,-3.402,2.072,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.0495842,0.00443048,0.966011 beta-lactamase_156_L197V,beta-lactamase_156_197,TEM-1,beta-lactamase_156,P62593,0.966018,NO,197,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.853,-2.903,2.05,,0.007,S,B,0.55,0.33,1.58,,60.14,HHP,-1.833,0.111618,0.00144602,0.966018 beta-lactamase_A225F,beta-lactamase_225,TEM-1,beta-lactamase,P62593,0.966039,NO,225,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.845,-4.402,2.557,6.5181,1,T,B,0.58,-0.38,4.077,,74.48,OHO,-1.39967,0.221079,0.00465057,0.966039 beta-lactamase_E210T,beta-lactamase_210,TEM-1,beta-lactamase,P62593,0.966039,NO,210,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.319,-2.842,0.523,5.7398,0.476,H,A,0.52,0.75,1.555,,77.62,HAH,-1.88567,0.221079,0.00663582,0.966039 beta-lactamase_M180D,beta-lactamase_180,TEM-1,beta-lactamase,P62593,0.966039,NO,180,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-2.795,-3.594,0.799,4.96809,0.242,,B,1.07,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.221079,0.00552048,0.966039 beta-lactamase_39_D252W,beta-lactamase_39_252,TEM-1,beta-lactamase_39,P62593,0.966047,NO,252,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.0495842,0.00575769,0.966047 beta-lactamase_39_K254V,beta-lactamase_39_254,TEM-1,beta-lactamase_39,P62593,0.966066,NO,254,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.0495842,0.00369,0.966066 beta-lactamase_G39V,beta-lactamase_39,TEM-1,beta-lactamase,P62593,0.966066,NO,39,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.864,-3.813,1.949,5.35574,0.701,T,L,0.23,0.47,29.926,29.926,77.62,HOH,-1.53633,0.221079,0.00487611,0.966066 Pab1_I183A,Pab1_183,Pab1,Pab1,P04147,0.966067,NO,183,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.302,-2.888,1.586,,0.308,T,B,1,1.08,1.29,,75.56,HHA,-1.27167,0.175299,0.000574345,0.966067 beta-lactamase_625_T187C,beta-lactamase_625_187,TEM-1,beta-lactamase_625,P62593,0.966073,NO,187,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.401,-4.859,3.458,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.213352,0.00491782,0.966073 beta-lactamase_I3T,beta-lactamase_3,TEM-1,beta-lactamase,P62593,0.966081,NO,3,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-2.143,-3.363,1.22,,,,,,,3.946,,93.01,PHP,-2.21633,0.221079,0.00349304,0.966081 beta-lactamase_P172H,beta-lactamase_172,TEM-1,beta-lactamase,P62593,0.966081,NO,172,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.998,-4.746,3.748,5.98941,0.639,T,b,1.1,0.24,2.087,,74.48,HOP,-2.03067,0.221079,0.00312594,0.966081 gb1_T244N,gb1_244,gb1,gb1,P06654,0.966093,NO,244,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.637,-3.54,1.903,,,,,,,0.202,,11.83,PPA,-1.92567,0.177985,0.00222755,0.966093 kka2_1:2_M116V,kka2_1:2_116,Kka2,kka2_1:2,P00552,0.966095,NO,116,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-2.482,-2.282,-0.2,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.295029,0.00745147,0.966095 beta-lactamase_39_E62W,beta-lactamase_39_62,TEM-1,beta-lactamase_39,P62593,0.966096,NO,62,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.193,-5.409,4.216,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.0495842,0.00264802,0.966096 beta-lactamase_39_K232R,beta-lactamase_39_232,TEM-1,beta-lactamase_39,P62593,0.966115,NO,232,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.012,-1.888,0.876,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.0495842,0.00313441,0.966115 beta-lactamase_39_W208G,beta-lactamase_39_208,TEM-1,beta-lactamase_39,P62593,0.966125,NO,208,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-0.818,-3.358,2.54,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.0495842,0.00126609,0.966125 beta-lactamase_0_A246R,beta-lactamase_0_246,TEM-1,beta-lactamase_0,P62593,0.966133,NO,246,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.121,-4.154,2.033,,0.01,E,B,0.46,-1.01,1.201,,73.78,HHH,-1.55633,0.0500837,0.00569458,0.966133 beta-lactamase_0_A211L,beta-lactamase_0_211,TEM-1,beta-lactamase_0,P62593,0.966148,NO,211,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.896,-3.595,1.699,,0.369,T,A,0.46,-0.69,8.527,8.527,77.62,AHA,-1.94633,0.0500837,0.00648183,0.966148 beta-lactamase_156_D271K,beta-lactamase_156_271,TEM-1,beta-lactamase_156,P62593,0.966149,NO,271,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.111618,0.00752082,0.966149 beta-lactamase_0_L167C,beta-lactamase_0_167,TEM-1,beta-lactamase_0,P62593,0.96616,NO,167,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.138,-4.763,3.625,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.0500837,0.00303566,0.96616 beta-lactamase_39_L192C,beta-lactamase_39_192,TEM-1,beta-lactamase_39,P62593,0.966185,NO,192,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.254,-4.743,3.489,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.0495842,0.00558728,0.966185 hsp90_N588H,hsp90_588,hsp90,hsp90,P02829,0.966191,NO,588,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-3.051,-3.833,0,4.61142,0.019,H,A,0.14,0.39,,,,HPH,-3.12167,0.368192,0.000222939,0.966191 beta-lactamase_156_H287Y,beta-lactamase_156_287,TEM-1,beta-lactamase_156,P62593,0.966219,NO,287,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,,,,,,,,,,,,,BBH,-1.111,0.111618,,0.966219 beta-lactamase_2500_E46L,beta-lactamase_2500_46,TEM-1,beta-lactamase_2500,P62593,0.966223,NO,46,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.94,-2.216,0.276,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.361275,0.00427568,0.966223 beta-lactamase_39_D83Q,beta-lactamase_39_83,TEM-1,beta-lactamase_39,P62593,0.966239,NO,83,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.066,-3.681,2.615,,0.354,H,A,0.75,0.22,0.752,,48.95,HAH,-1.34733,0.0495842,0.00205968,0.966239 beta-lactamase_K252F,beta-lactamase_252,TEM-1,beta-lactamase,P62593,0.966242,NO,252,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.94,-4.435,2.495,5.56823,0.766,,B,1.82,1.16,21.796,21.796,67.83,OBO,-2.03333,0.221079,0.00575769,0.966242 beta-lactamase_39_G52Y,beta-lactamase_39_52,TEM-1,beta-lactamase_39,P62593,0.966243,NO,52,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.149,-4.436,3.287,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.0495842,0.00340138,0.966243 beta-lactamase_625_T264I,beta-lactamase_625_264,TEM-1,beta-lactamase_625,P62593,0.966258,NO,264,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.213352,0.0119399,0.966258 beta-lactamase_0_A182E,beta-lactamase_0_182,TEM-1,beta-lactamase_0,P62593,0.966269,NO,182,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.777,-2.345,0.568,,0.136,H,A,0.46,-0.66,10.765,10.765,93.01,OHH,-1.27367,0.0500837,0.00559099,0.966269 beta-lactamase_156_E102H,beta-lactamase_156_102,TEM-1,beta-lactamase_156,P62593,0.966269,NO,102,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.118,-3.309,1.191,,0.722,S,B,1.04,1.82,15.721,15.721,73.08,HAH,-1.581,0.111618,0.00486633,0.966269 kka2_1:4_A110R,kka2_1:4_110,Kka2,kka2_1:4,P00552,0.966281,NO,110,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.064,-3.093,1.029,,0.175,H,A,0.46,-1.19,23.237,23.237,71.59,OHA,-1.91867,0.168804,0.00759851,0.966281 beta-lactamase_N130N,beta-lactamase_130,TEM-1,beta-lactamase,P62593,0.966289,NO,130,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-0.798,-0.798,,5.26686,0.069,H,A,1.08,-0.74,,,,APP,-0.980667,0.221079,0.000683376,0.966289 kka2_1:4_A215C,kka2_1:4_215,Kka2,kka2_1:4,P00552,0.966292,NO,215,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.968,-4.591,3.623,,0.039,E,B,0.46,-0.59,0.754,,50.38,HHA,-1.00467,0.168804,0.00529129,0.966292 PSD95pdz3_G344M,PSD95pdz3_344,PSD95pdz3,PSD95pdz3,P31016,0.966319,NO,344,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.008,-4.612,3.604,4.83855,,,,,14.06,,,,HOO,-1.10767,0.0758425,0.00078498,0.966319 beta-lactamase_E210N,beta-lactamase_210,TEM-1,beta-lactamase,P62593,0.966335,NO,210,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.319,-3.904,1.585,5.7398,0.476,H,A,0.52,0.75,1.555,,77.62,HAH,-1.88567,0.221079,0.00663582,0.966335 beta-lactamase_0_A34T,beta-lactamase_0_34,TEM-1,beta-lactamase_0,P62593,0.966354,NO,34,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.059,-2.5,0.441,,,H,A,0.46,-0.54,3.998,,73.78,AHA,-1.74967,0.0500837,0.00407913,0.966354 beta-lactamase_0_Q37G,beta-lactamase_0_37,TEM-1,beta-lactamase_0,P62593,0.966355,NO,37,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.134,-3.507,1.373,,0.613,H,A,0.64,1.98,4.001,,73.08,APH,-2.06967,0.0500837,0.00425833,0.966355 PSD95pdz3_D332M,PSD95pdz3_332,PSD95pdz3,PSD95pdz3,P31016,0.966367,NO,332,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.264,-4.612,3.348,6.09878,,,,,48.762,,,,AAO,-1.22533,0.0758425,0.000937818,0.966367 beta-lactamase_625_R41K,beta-lactamase_625_41,TEM-1,beta-lactamase_625,P62593,0.966388,NO,41,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-0.942,-2.85,1.908,,0.321,E,B,1.2,-0.07,1.186,,65.03,HBH,-1.30267,0.213352,0.00123327,0.966388 kka2_1:1_D33S,kka2_1:1_33,Kka2,kka2_1:1,P00552,0.966399,NO,33,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.186,-2.451,0.265,,0.561,S,A,0.75,3.35,2.568,,71.59,PAH,-1.306,0.520039,0.00633568,0.966399 beta-lactamase_625_R176K,beta-lactamase_625_176,TEM-1,beta-lactamase_625,P62593,0.96641,NO,176,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-0.863,-2.782,1.919,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.213352,0.00105554,0.96641 beta-lactamase_D207I,beta-lactamase_207,TEM-1,beta-lactamase,P62593,0.966422,NO,207,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.064,-4.165,2.101,5.40404,0.409,H,A,0.23,0.12,1.975,,77.62,HAH,-1.77033,0.221079,0.00592942,0.966422 beta-lactamase_E277K,beta-lactamase_277,TEM-1,beta-lactamase,P62593,0.966422,NO,277,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.869,-2.835,0.966,5.51786,0.545,H,A,0.52,-0.01,2.022,,77.62,HAH,-1.45367,0.221079,0.0169305,0.966422 kka2_1:8_A222S,kka2_1:8_222,Kka2,kka2_1:8,P00552,0.966438,NO,222,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.725,-2.964,2.239,,,H,A,1.04,-1.21,,,,HHH,-1.10833,0.100394,0.00207657,0.966438 kka2_1:8_A222S,kka2_1:8_222,Kka2,kka2_1:8,P00552,0.966438,NO,222,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.725,-2.964,2.239,,,H,A,1.04,-1.21,,,,HHH,-1.10833,0.100394,0.00207657,0.966438 beta-lactamase_2500_H287T,beta-lactamase_2500_287,TEM-1,beta-lactamase_2500,P62593,0.966442,NO,287,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,,,,,,,,,,,,,BBH,-1.111,0.361275,,0.966442 beta-lactamase_39_D33M,beta-lactamase_39_33,TEM-1,beta-lactamase_39,P62593,0.966449,NO,33,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.321,-4.607,2.286,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.0495842,0.00435556,0.966449 beta-lactamase_0_R239I,beta-lactamase_0_239,TEM-1,beta-lactamase_0,P62593,0.96645,NO,239,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.0500837,0.00213852,0.96645 beta-lactamase_T138L,beta-lactamase_138,TEM-1,beta-lactamase,P62593,0.966464,NO,138,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.506,-3.638,1.132,5.52585,0.662,H,A,0.3,-0.03,30.445,30.445,73.78,HPP,-1.81233,0.221079,0.00487868,0.966464 beta-lactamase_39_L284V,beta-lactamase_39_284,TEM-1,beta-lactamase_39,P62593,0.966496,NO,284,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.0495842,0.0686156,0.966496 beta-lactamase_156_P105H,beta-lactamase_156_105,TEM-1,beta-lactamase_156,P62593,0.966506,NO,105,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.813,-4.678,3.865,,0.226,T,A,0.52,0.8,1.154,,63.29,POH,-1.01533,0.111618,0.0011981,0.966506 beta-lactamase_A222A,beta-lactamase_222,TEM-1,beta-lactamase,P62593,0.966524,NO,222,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.103,-2.103,,5.2262,0.233,H,A,0.47,-0.25,0.379,,77.62,PHH,-1.63733,0.221079,0.00466094,0.966524 beta-lactamase_I259L,beta-lactamase_259,TEM-1,beta-lactamase,P62593,0.96653,NO,259,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.522,-2.081,0.559,5.28457,,E,B,1,-0.8,1.24,,64.34,HHH,-1.53267,0.221079,0.0070773,0.96653 beta-lactamase_156_L197I,beta-lactamase_156_197,TEM-1,beta-lactamase_156,P62593,0.966534,NO,197,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.853,-2.968,2.115,,0.007,S,B,0.55,0.33,1.58,,60.14,HHP,-1.833,0.111618,0.00144602,0.966534 beta-lactamase_156_R257K,beta-lactamase_156_257,TEM-1,beta-lactamase_156,P62593,0.966538,NO,257,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.111618,0.00756629,0.966538 kka2_1:8_G99D,kka2_1:8_99,Kka2,kka2_1:8,P00552,0.966547,NO,99,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.596,-3.497,2.901,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.100394,0.00186055,0.966547 kka2_1:8_G99D,kka2_1:8_99,Kka2,kka2_1:8,P00552,0.966547,NO,99,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.596,-3.497,2.901,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.100394,0.00186055,0.966547 beta-lactamase_625_L89G,beta-lactamase_625_89,TEM-1,beta-lactamase_625,P62593,0.966548,NO,89,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.096,-3.653,2.557,,0.168,T,A,0.55,0.63,1.599,,64.34,PHO,-1.75767,0.213352,0.00207068,0.966548 beta-lactamase_39_I206S,beta-lactamase_39_206,TEM-1,beta-lactamase_39,P62593,0.96655,NO,206,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-2.429,-3.468,1.039,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.0495842,0.00528934,0.96655 beta-lactamase_2500_M153S,beta-lactamase_2500_153,TEM-1,beta-lactamase_2500,P62593,0.966553,NO,153,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-3.193,-2.433,-0.76,,0.14,T,A,0.55,-0.11,3.409,,77.62,PHO,-2.25767,0.361275,0.00509109,0.966553 beta-lactamase_39_A34D,beta-lactamase_39_34,TEM-1,beta-lactamase_39,P62593,0.966571,NO,34,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.059,-3.876,1.817,,,H,A,0.46,-0.54,13.292,13.292,73.78,AHA,-1.74967,0.0495842,0.00407913,0.966571 kka2_1:2_R18C,kka2_1:2_18,Kka2,kka2_1:2,P00552,0.966579,NO,18,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.055,-5.174,3.119,,0.474,T,A,1.2,0.54,8.405,8.405,71.59,ABH,-1.821,0.295029,0.00724065,0.966579 kka2_1:8_L243V,kka2_1:8_243,Kka2,kka2_1:8,P00552,0.966583,NO,243,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-2.651,-2.869,0.218,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.100394,0.00884927,0.966583 kka2_1:8_L243V,kka2_1:8_243,Kka2,kka2_1:8,P00552,0.966583,NO,243,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-2.651,-2.869,0.218,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.100394,0.00884927,0.966583 beta-lactamase_39_P143H,beta-lactamase_39_143,TEM-1,beta-lactamase_39,P62593,0.966586,NO,143,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.967,-4.789,3.822,,0.075,H,A,0.52,-0.37,0.976,,66.78,OOB,-1.354,0.0495842,0.00114551,0.966586 beta-lactamase_156_Q203C,beta-lactamase_156_203,TEM-1,beta-lactamase_156,P62593,0.966598,NO,203,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.168,-5.086,2.918,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.111618,0.00631514,0.966598 beta-lactamase_39_E56M,beta-lactamase_39_56,TEM-1,beta-lactamase_39,P62593,0.96662,NO,56,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.043,-4.624,2.581,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.0495842,0.00238534,0.96662 beta-lactamase_156_H287C,beta-lactamase_156_287,TEM-1,beta-lactamase_156,P62593,0.966639,NO,287,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,,,,,,,,,,,,,BBH,-1.111,0.111618,,0.966639 beta-lactamase_39_A123Y,beta-lactamase_39_123,TEM-1,beta-lactamase_39,P62593,0.966648,NO,123,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.834,-4.16,3.326,,0.039,H,A,0.46,-0.72,0.705,,41.26,PHH,-1.47367,0.0495842,0.0010157,0.966648 beta-lactamase_I229C,beta-lactamase_229,TEM-1,beta-lactamase,P62593,0.966655,NO,229,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.267,-4.722,3.455,5.0911,0.083,E,B,1,-0.76,1.114,,50,HHH,-1.58767,0.221079,0.00477249,0.966655 beta-lactamase_P172C,beta-lactamase_172,TEM-1,beta-lactamase,P62593,0.966655,NO,172,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.998,-4.977,3.979,5.98941,0.639,T,b,1.1,0.24,2.087,,74.48,HOP,-2.03067,0.221079,0.00312594,0.966655 beta-lactamase_0_K53A,beta-lactamase_0_53,TEM-1,beta-lactamase_0,P62593,0.966661,NO,53,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-2.313,-2.735,0.422,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.0500837,0.00383383,0.966661 beta-lactamase_2500_M115L,beta-lactamase_2500_115,TEM-1,beta-lactamase_2500,P62593,0.966666,NO,115,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.389,-1.859,0.47,,0.019,E,B,0.55,0.08,3.261,,69.58,OHP,-1.25433,0.361275,0.0034337,0.966666 beta-lactamase_2500_R92Q,beta-lactamase_2500_92,TEM-1,beta-lactamase_2500,P62593,0.96668,NO,92,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.718,-3.029,1.311,,0.479,E,B,1.2,1.36,3.069,,65.38,BBH,-1.50367,0.361275,0.00429626,0.96668 beta-lactamase_39_T158C,beta-lactamase_39_158,TEM-1,beta-lactamase_39,P62593,0.966703,NO,158,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.116,-4.748,3.632,,0.036,,B,0.22,-0.85,2.755,,69.58,HPB,-1.269,0.0495842,0.00341825,0.966703 Pab1_E175G,Pab1_175,Pab1,Pab1,P04147,0.966703,NO,175,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.055,-3.199,1.144,,,,,,,,,,AAA,-1.82667,0.175299,0.00203137,0.966703 beta-lactamase_2500_E108L,beta-lactamase_2500_108,TEM-1,beta-lactamase_2500,P62593,0.966709,NO,108,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.46,-3.653,2.193,,0.572,G,A,1.04,1.87,1.147,,72.73,PAB,-1.437,0.361275,0.00413372,0.966709 beta-lactamase_156_W208I,beta-lactamase_156_208,TEM-1,beta-lactamase_156,P62593,0.966725,NO,208,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-0.818,-4.01,3.192,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.111618,0.00126609,0.966725 beta-lactamase_39_G52K,beta-lactamase_39_52,TEM-1,beta-lactamase_39,P62593,0.966743,NO,52,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.149,-3.631,2.482,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.0495842,0.00340138,0.966743 beta-lactamase_0_A282Y,beta-lactamase_0_282,TEM-1,beta-lactamase_0,P62593,0.96675,NO,282,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.0500837,0.0449821,0.96675 beta-lactamase_G226K,beta-lactamase_226,TEM-1,beta-lactamase,P62593,0.966758,NO,226,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.461,-2.859,1.398,5.70682,0.701,T,l,0.77,-0.25,3.199,,74.48,HOH,-1.42933,0.221079,0.00665294,0.966758 kka2_1:2_Q100M,kka2_1:2_100,Kka2,kka2_1:2,P00552,0.966774,NO,100,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.77,-3.639,0.869,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.295029,0.0066405,0.966774 beta-lactamase_2500_E102R,beta-lactamase_2500_102,TEM-1,beta-lactamase_2500,P62593,0.966776,NO,102,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.118,-3.801,1.683,,0.722,S,B,1.04,1.82,1.336,,73.08,HAH,-1.581,0.361275,0.00486633,0.966776 beta-lactamase_2500_R239M,beta-lactamase_2500_239,TEM-1,beta-lactamase_2500,P62593,0.966779,NO,239,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.361275,0.00213852,0.966779 beta-lactamase_2500_D33N,beta-lactamase_2500_33,TEM-1,beta-lactamase_2500,P62593,0.96678,NO,33,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.321,-2.983,0.662,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.361275,0.00435556,0.96678 beta-lactamase_625_A225Q,beta-lactamase_625_225,TEM-1,beta-lactamase_625,P62593,0.96678,NO,225,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.845,-2.909,1.064,,1,T,B,0.46,-0.38,9.874,9.874,74.48,OHO,-1.39967,0.213352,0.00465057,0.96678 beta-lactamase_F6L,beta-lactamase_6,TEM-1,beta-lactamase,P62593,0.96679,NO,6,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.847,-2.707,0.86,,,,,,,1.276,,67.83,BHB,-2.076,0.221079,0.00261627,0.96679 beta-lactamase_39_A215M,beta-lactamase_39_215,TEM-1,beta-lactamase_39,P62593,0.9668,NO,215,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.503,-4.708,3.205,,,,a,0.46,-0.93,0.494,,74.48,HHO,-1.42633,0.0495842,0.00544007,0.9668 Pab1_E181V,Pab1_181,Pab1,Pab1,P04147,0.966803,NO,181,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.767,-3.303,1.536,,,,,,,1.395,,73.83,BAH,-1.575,0.175299,0.00107557,0.966803 beta-lactamase_0_A185Q,beta-lactamase_0_185,TEM-1,beta-lactamase_0,P62593,0.966808,NO,185,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.406,-4.108,2.702,,,H,A,0.46,-1.02,1.203,,65.03,HHP,-1.84033,0.0500837,0.00467449,0.966808 WW_domain_M179A,WW_domain_179,Yap65,WW_domain,P46937,0.966847,NO,179,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.541,-2.855,1.314,6.54704,,,,,,,,,AHH,-1.31367,0.153962,0.00400164,0.966847 beta-lactamase_0_R239V,beta-lactamase_0_239,TEM-1,beta-lactamase_0,P62593,0.966851,NO,239,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.0500837,0.00213852,0.966851 beta-lactamase_156_E62F,beta-lactamase_156_62,TEM-1,beta-lactamase_156,P62593,0.966854,NO,62,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.193,-4.376,3.183,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.111618,0.00264802,0.966854 beta-lactamase_156_K254F,beta-lactamase_156_254,TEM-1,beta-lactamase_156,P62593,0.966855,NO,254,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.111618,0.00369,0.966855 kka2_1:8_Y218I,kka2_1:8_218,Kka2,kka2_1:8,P00552,0.966856,NO,218,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-1.438,-3.85,2.412,,0.122,H,A,1.25,-0.69,2.923,,56.06,BHP,-1.17533,0.100394,0.0126098,0.966856 kka2_1:8_Y218I,kka2_1:8_218,Kka2,kka2_1:8,P00552,0.966856,NO,218,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-1.438,-3.85,2.412,,0.122,H,A,1.25,-0.69,2.923,,56.06,BHP,-1.17533,0.100394,0.0126098,0.966856 Pab1_D160I,Pab1_160,Pab1,Pab1,P04147,0.966857,NO,160,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.985,-3.827,2.842,,0.396,B,B,,1.12,,,,PAA,-1.30133,0.175299,0.000311977,0.966857 kka2_1:2_L152I,kka2_1:2_152,Kka2,kka2_1:2,P00552,0.966882,NO,152,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.521,-2.522,1.001,,0.547,.,A,0.55,1.36,4.526,,63.64,OHH,-1.162,0.295029,0.00674868,0.966882 beta-lactamase_2500_A225Y,beta-lactamase_2500_225,TEM-1,beta-lactamase_2500,P62593,0.966884,NO,225,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.845,-4.327,2.482,,1,T,B,0.46,-0.38,0.551,,74.48,OHO,-1.39967,0.361275,0.00465057,0.966884 beta-lactamase_2500_Q203E,beta-lactamase_2500_203,TEM-1,beta-lactamase_2500,P62593,0.966887,NO,203,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.168,-2.449,0.281,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.361275,0.00631514,0.966887 beta-lactamase_2500_N152Y,beta-lactamase_2500_152,TEM-1,beta-lactamase_2500,P62593,0.966897,NO,152,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-2.757,-4.312,1.555,,0.863,H,A,0.61,0.92,2.061,,77.62,BPH,-2.97,0.361275,0.00471429,0.966897 kka2_1:4_R122D,kka2_1:4_122,Kka2,kka2_1:4,P00552,0.966898,NO,122,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.175,-2.452,0.277,,0.487,H,A,0.16,0.26,16.436,16.436,71.59,BBH,-1.53833,0.168804,0.00736512,0.966898 beta-lactamase_39_T263E,beta-lactamase_39_263,TEM-1,beta-lactamase_39,P62593,0.96691,NO,263,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.0495842,0.0110582,0.96691 beta-lactamase_E145I,beta-lactamase_145,TEM-1,beta-lactamase,P62593,0.966913,NO,145,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.357,-4.11,1.753,5.38104,0.545,H,A,0.52,0.79,2.124,,77.62,BAH,-2.069,0.221079,0.00553285,0.966913 beta-lactamase_625_D83N,beta-lactamase_625_83,TEM-1,beta-lactamase_625,P62593,0.966915,NO,83,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.066,-3.355,2.289,,0.354,H,A,0.75,0.22,0.239,,48.95,HAH,-1.34733,0.213352,0.00205968,0.966915 PSD95pdz3_K393A,PSD95pdz3_393,PSD95pdz3,PSD95pdz3,P31016,0.966919,NO,393,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.416,-2.759,1.343,5.42682,,,,,22.0122,,,,HBO,-1.4265,0.0758425,0.000879298,0.966919 Pab1_D136N,Pab1_136,Pab1,Pab1,P04147,0.96692,NO,136,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.602,-3.53,1.928,,,,,,,,,,OAH,-1.42367,0.175299,0.00227029,0.96692 beta-lactamase_39_T147F,beta-lactamase_39_147,TEM-1,beta-lactamase_39,P62593,0.966922,NO,147,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.149,-4.147,2.998,,0.281,H,A,0.22,-0.68,13.843,13.843,64.34,HPH,-1.456,0.0495842,0.00226017,0.966922 beta-lactamase_625_Q203I,beta-lactamase_625_203,TEM-1,beta-lactamase_625,P62593,0.966937,NO,203,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.168,-3.973,1.805,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.213352,0.00631514,0.966937 beta-lactamase_39_D83F,beta-lactamase_39_83,TEM-1,beta-lactamase_39,P62593,0.966939,NO,83,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.066,-4.344,3.278,,0.354,H,A,0.75,0.22,0.752,,48.95,HAH,-1.34733,0.0495842,0.00205968,0.966939 beta-lactamase_39_G142H,beta-lactamase_39_142,TEM-1,beta-lactamase_39,P62593,0.966945,NO,142,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.707,-4.678,3.971,,0.034,,p,0.29,-0.64,1.947,,64.69,OOO,-0.834,0.0495842,0.00060149,0.966945 beta-lactamase_625_D207Q,beta-lactamase_625_207,TEM-1,beta-lactamase_625,P62593,0.966946,NO,207,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.064,-2.209,0.145,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.213352,0.00592942,0.966946 beta-lactamase_156_T139H,beta-lactamase_156_139,TEM-1,beta-lactamase_156,P62593,0.96699,NO,139,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.901,-3.291,1.39,,0.216,H,A,0.22,0.39,16.34,16.34,77.62,PPH,-2.04667,0.111618,0.00441837,0.96699 beta-lactamase_39_T193Y,beta-lactamase_39_193,TEM-1,beta-lactamase_39,P62593,0.967002,NO,193,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.914,-3.989,2.075,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.0495842,0.00482669,0.967002 beta-lactamase_2500_K286Y,beta-lactamase_2500_286,TEM-1,beta-lactamase_2500,P62593,0.967009,NO,286,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.361275,,0.967009 Pab1_Y143L,Pab1_143,Pab1,Pab1,P04147,0.967011,NO,143,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-1.961,-3.234,1.273,,0.409,H,A,,0.3,,,,HHA,-1.39633,0.175299,0.00160364,0.967011 beta-lactamase_156_A268W,beta-lactamase_156_268,TEM-1,beta-lactamase_156,P62593,0.967014,NO,268,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.111618,0.0102525,0.967014 beta-lactamase_156_G253F,beta-lactamase_156_253,TEM-1,beta-lactamase_156,P62593,0.967022,NO,253,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.111618,0.00786358,0.967022 beta-lactamase_I3F,beta-lactamase_3,TEM-1,beta-lactamase,P62593,0.967024,NO,3,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-2.143,-3.724,1.581,,,,,,,3.946,,93.01,PHP,-2.21633,0.221079,0.00349304,0.967024 beta-lactamase_L218M,beta-lactamase_218,TEM-1,beta-lactamase,P62593,0.967024,NO,218,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.391,-4.267,2.876,4.88972,,I,b,2.89,-0.53,12.788,12.788,74.48,OHH,-1.58867,0.221079,0.00618274,0.967024 beta-lactamase_39_I245Y,beta-lactamase_39_245,TEM-1,beta-lactamase_39,P62593,0.967041,NO,245,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.0495842,0.00391032,0.967041 beta-lactamase_0_D83E,beta-lactamase_0_83,TEM-1,beta-lactamase_0,P62593,0.967047,NO,83,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.066,-2.025,0.959,,0.354,H,A,0.75,0.22,0.617,,48.95,HAH,-1.34733,0.0500837,0.00205968,0.967047 beta-lactamase_39_T139R,beta-lactamase_39_139,TEM-1,beta-lactamase_39,P62593,0.967048,NO,139,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.901,-2.238,0.337,,0.216,H,A,0.22,0.39,0.421,,77.62,PPH,-2.04667,0.0495842,0.00441837,0.967048 beta-lactamase_39_Q37H,beta-lactamase_39_37,TEM-1,beta-lactamase_39,P62593,0.967055,NO,37,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.134,-3.314,1.18,,0.613,H,A,0.64,1.98,22.282,22.282,73.08,APH,-2.06967,0.0495842,0.00425833,0.967055 beta-lactamase_2500_A183E,beta-lactamase_2500_183,TEM-1,beta-lactamase_2500,P62593,0.967059,NO,183,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.231,-3.42,2.189,,0.155,H,A,0.46,-0.91,12.189,,77.62,HHH,-1.53367,0.361275,0.00296631,0.967059 beta-lactamase_156_T263E,beta-lactamase_156_263,TEM-1,beta-lactamase_156,P62593,0.967062,NO,263,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.111618,0.0110582,0.967062 beta-lactamase_Q37G,beta-lactamase_37,TEM-1,beta-lactamase,P62593,0.967075,NO,37,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.134,-3.507,1.373,5.69153,0.613,H,A,0.12,1.98,1.318,,73.08,APH,-2.06967,0.221079,0.00425833,0.967075 beta-lactamase_625_L49Q,beta-lactamase_625_49,TEM-1,beta-lactamase_625,P62593,0.967076,NO,49,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.897,-2.823,0.926,,0.131,T,A,0.55,0.04,3.112,,64.69,AHP,-1.99233,0.213352,0.00401477,0.967076 beta-lactamase_0_R162W,beta-lactamase_0_162,TEM-1,beta-lactamase_0,P62593,0.967077,NO,162,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.016,-5.367,4.351,,0.124,S,B,1.2,-0.37,1.026,,64.69,ABH,-1.25,0.0500837,0.000561334,0.967077 beta-lactamase_156_D48G,beta-lactamase_156_48,TEM-1,beta-lactamase_156,P62593,0.967081,NO,48,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.101,-3.259,2.158,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.111618,0.0027273,0.967081 beta-lactamase_39_D36M,beta-lactamase_39_36,TEM-1,beta-lactamase_39,P62593,0.967088,NO,36,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.732,-4.763,2.031,,0.555,H,A,0.75,1.17,13.689,13.689,77.62,AAP,-1.91167,0.0495842,0.00476483,0.967088 beta-lactamase_39_D36V,beta-lactamase_39_36,TEM-1,beta-lactamase_39,P62593,0.967099,NO,36,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.732,-3.726,0.994,,0.555,H,A,0.75,1.17,13.689,13.689,77.62,AAP,-1.91167,0.0495842,0.00476483,0.967099 kka2_1:2_R173F,kka2_1:2_173,Kka2,kka2_1:2,P00552,0.967123,NO,173,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.407,-4.245,1.838,,0.308,H,A,0.16,-0.13,15.389,15.389,65.53,HBH,-1.70533,0.295029,0.00784999,0.967123 beta-lactamase_D250V,beta-lactamase_250,TEM-1,beta-lactamase,P62593,0.967144,NO,250,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.335,-3.657,1.322,5.72026,0.89,T,L,0.23,1.53,24.737,24.737,66.08,OAO,-1.85133,0.221079,0.00550899,0.967144 beta-lactamase_39_D252L,beta-lactamase_39_252,TEM-1,beta-lactamase_39,P62593,0.967175,NO,252,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.0495842,0.00575769,0.967175 beta-lactamase_156_L100F,beta-lactamase_156_100,TEM-1,beta-lactamase_156,P62593,0.967182,NO,100,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.218,-3.677,2.459,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.111618,0.00413885,0.967182 beta-lactamase_39_A77Q,beta-lactamase_39_77,TEM-1,beta-lactamase_39,P62593,0.967201,NO,77,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.234,-4.052,2.818,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.0495842,0.00282362,0.967201 kka2_1:8_D156V,kka2_1:8_156,Kka2,kka2_1:8,P00552,0.967201,NO,156,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.696,-3.632,1.936,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.100394,0.00926998,0.967201 kka2_1:8_D156V,kka2_1:8_156,Kka2,kka2_1:8,P00552,0.967201,NO,156,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.696,-3.632,1.936,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.100394,0.00926998,0.967201 beta-lactamase_2500_W163Y,beta-lactamase_2500_163,TEM-1,beta-lactamase_2500,P62593,0.967211,NO,163,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-1.843,-3.906,2.063,,0.467,,B,0.47,-0.5,32.624,32.624,63.99,BHA,-1.269,0.361275,0.00418955,0.967211 beta-lactamase_0_P60S,beta-lactamase_0_60,TEM-1,beta-lactamase_0,P62593,0.967217,NO,60,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-2.469,-2.362,-0.107,,0.256,T,A,0.52,-0.56,3.653,,77.62,BOA,-1.97633,0.0500837,0.00521318,0.967217 beta-lactamase_156_T69M,beta-lactamase_156_69,TEM-1,beta-lactamase_156,P62593,0.967228,NO,69,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-0.973,-4.54,3.567,,,G,A,0.22,-1.24,4.194,,93.01,PPH,-1.01833,0.111618,0.00127498,0.967228 beta-lactamase_39_A40C,beta-lactamase_39_40,TEM-1,beta-lactamase_39,P62593,0.967242,NO,40,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.402,-4.779,3.377,,0.155,S,B,0.46,0.21,0.783,,73.78,OHB,-1.40267,0.0495842,0.00490026,0.967242 beta-lactamase_0_A282M,beta-lactamase_0_282,TEM-1,beta-lactamase_0,P62593,0.967255,NO,282,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.0500837,0.0449821,0.967255 beta-lactamase_0_S266T,beta-lactamase_0_266,TEM-1,beta-lactamase_0,P62593,0.967264,NO,266,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.0500837,0.0140785,0.967264 kka2_1:4_W15L,kka2_1:4_15,Kka2,kka2_1:4,P00552,0.967273,NO,15,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-1.392,-1.643,0.251,,0.01,G,A,0.47,0.15,0.943,,52.27,HHH,-2.10533,0.168804,0.00585505,0.967273 E1_Ubiquitin_L71H,E1_Ubiquitin_71,Uba1,E1_Ubiquitin,P0CG63,0.967286,NO,71,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.039,-4.722,3.683,,0.591,E,B,,-0.69,,,,BHB,-1.19433,0.18783,0.00148349,0.967286 E1_Ubiquitin_R74R,E1_Ubiquitin_74,Uba1,E1_Ubiquitin,P0CG63,0.967286,NO,74,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.302,-1.302,,,0.838,T,A,,3.15,,,,HBO,-1.11333,0.18783,0.00180798,0.967286 beta-lactamase_P217S,beta-lactamase_217,TEM-1,beta-lactamase,P62593,0.967288,NO,217,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-2.062,-2.615,0.553,5.19872,0.496,I,A,0.99,-0.33,0.431,,74.48,OOH,-1.64333,0.221079,0.00463211,0.967288 beta-lactamase_39_T179V,beta-lactamase_39_179,TEM-1,beta-lactamase_39,P62593,0.967299,NO,179,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.085,-3.247,2.162,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.0495842,0.00226045,0.967299 beta-lactamase_39_W288H,beta-lactamase_39_288,TEM-1,beta-lactamase_39,P62593,0.967305,NO,288,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,,,,,,,,,,,,,BHO,,0.0495842,,0.967305 beta-lactamase_156_A282I,beta-lactamase_156_282,TEM-1,beta-lactamase_156,P62593,0.967313,NO,282,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.111618,0.0449821,0.967313 beta-lactamase_39_D83W,beta-lactamase_39_83,TEM-1,beta-lactamase_39,P62593,0.967323,NO,83,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.066,-5.509,4.443,,0.354,H,A,0.75,0.22,0.752,,48.95,HAH,-1.34733,0.0495842,0.00205968,0.967323 beta-lactamase_39_D252T,beta-lactamase_39_252,TEM-1,beta-lactamase_39,P62593,0.967327,NO,252,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.0495842,0.00575769,0.967327 beta-lactamase_39_K254H,beta-lactamase_39_254,TEM-1,beta-lactamase_39,P62593,0.967332,NO,254,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.0495842,0.00369,0.967332 kka2_1:8_A215C,kka2_1:8_215,Kka2,kka2_1:8,P00552,0.967333,NO,215,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.968,-4.591,3.623,,0.039,E,B,1.04,-0.59,2.77,,50.38,HHA,-1.00467,0.100394,0.00529129,0.967333 kka2_1:8_A215C,kka2_1:8_215,Kka2,kka2_1:8,P00552,0.967333,NO,215,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.968,-4.591,3.623,,0.039,E,B,1.04,-0.59,2.77,,50.38,HHA,-1.00467,0.100394,0.00529129,0.967333 kka2_1:8_S204C,kka2_1:8_204,Kka2,kka2_1:8,P00552,0.967346,NO,204,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.353,-4.762,3.409,,0.144,E,A,0.27,-1.2,0.368,,65.53,HPO,-0.953333,0.100394,0.00881794,0.967346 kka2_1:8_S204C,kka2_1:8_204,Kka2,kka2_1:8,P00552,0.967346,NO,204,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.353,-4.762,3.409,,0.144,E,A,0.27,-1.2,0.368,,65.53,HPO,-0.953333,0.100394,0.00881794,0.967346 beta-lactamase_2500_A183Y,beta-lactamase_2500_183,TEM-1,beta-lactamase_2500,P62593,0.967365,NO,183,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.231,-4.261,3.03,,0.155,H,A,0.46,-0.91,12.189,,77.62,HHH,-1.53367,0.361275,0.00296631,0.967365 beta-lactamase_625_Q267F,beta-lactamase_625_267,TEM-1,beta-lactamase_625,P62593,0.967366,NO,267,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.213352,0.0102128,0.967366 beta-lactamase_L196L,beta-lactamase_196,TEM-1,beta-lactamase,P62593,0.967374,NO,196,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-2.478,-2.478,,,0.518,S,A,0.55,1.35,,,77.62,AHH,-1.839,0.221079,0.00512144,0.967374 PSD95pdz3_Q384N,PSD95pdz3_384,PSD95pdz3,PSD95pdz3,P31016,0.967377,NO,384,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-1.699,-3.13,1.431,5.49339,,,,,23.54,,,,OPP,-1.41333,0.0758425,0.000216736,0.967377 beta-lactamase_A222H,beta-lactamase_222,TEM-1,beta-lactamase,P62593,0.96738,NO,222,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.103,-2.705,0.602,5.2262,0.233,H,A,0.47,-0.25,0.379,,77.62,PHH,-1.63733,0.221079,0.00466094,0.96738 beta-lactamase_625_E62H,beta-lactamase_625_62,TEM-1,beta-lactamase_625,P62593,0.967389,NO,62,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.193,-4.429,3.236,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.213352,0.00264802,0.967389 kka2_1:8_L184Y,kka2_1:8_184,Kka2,kka2_1:8,P00552,0.967396,NO,184,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.496,-4.144,2.648,,0.489,E,B,0.55,-0.06,4.495,,63.26,AHH,-1.24833,0.100394,0.00518742,0.967396 kka2_1:8_L184Y,kka2_1:8_184,Kka2,kka2_1:8,P00552,0.967396,NO,184,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.496,-4.144,2.648,,0.489,E,B,0.55,-0.06,4.495,,63.26,AHH,-1.24833,0.100394,0.00518742,0.967396 beta-lactamase_39_Q203R,beta-lactamase_39_203,TEM-1,beta-lactamase_39,P62593,0.967398,NO,203,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.168,-2.451,0.283,,0.47,H,A,0.64,-0.38,1.453,,65.38,BPP,-1.614,0.0495842,0.00631514,0.967398 kka2_1:2_S251G,kka2_1:2_251,Kka2,kka2_1:2,P00552,0.967402,NO,251,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.636,-2.736,0.1,,0.712,H,A,0.27,-0.25,32.832,32.832,71.59,APP,-2.09367,0.295029,0.0138916,0.967402 beta-lactamase_0_E195W,beta-lactamase_0_195,TEM-1,beta-lactamase_0,P62593,0.967407,NO,195,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.186,-5.555,3.369,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.0500837,0.00496565,0.967407 beta-lactamase_39_S122F,beta-lactamase_39_122,TEM-1,beta-lactamase_39,P62593,0.967407,NO,122,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.406,-3.279,0.873,,0.352,H,A,0.27,-0.54,2.004,,77.62,OPH,-1.39767,0.0495842,0.00497825,0.967407 beta-lactamase_625_N98M,beta-lactamase_625_98,TEM-1,beta-lactamase_625,P62593,0.967409,NO,98,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-2.973,-4.74,1.767,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.213352,0.00505389,0.967409 beta-lactamase_2500_V157M,beta-lactamase_2500_157,TEM-1,beta-lactamase_2500,P62593,0.967415,NO,157,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.751,-2.587,0.836,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.361275,0.00506849,0.967415 beta-lactamase_39_P255Y,beta-lactamase_39_255,TEM-1,beta-lactamase_39,P62593,0.967418,NO,255,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.0495842,0.00499612,0.967418 Pab1_D184T,Pab1_184,Pab1,Pab1,P04147,0.967433,NO,184,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.5,-3.31,1.81,,,,,,,,,,HAH,-1.50133,0.175299,0.0011931,0.967433 beta-lactamase_2500_T269V,beta-lactamase_2500_269,TEM-1,beta-lactamase_2500,P62593,0.967436,NO,269,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.361275,0.00950944,0.967436 beta-lactamase_K284G,beta-lactamase_284,TEM-1,beta-lactamase,P62593,0.967452,NO,284,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.981,-3.365,1.384,6.30084,0.848,H,A,1.82,0.67,1.931,,77.62,HBB,-1.82133,0.221079,0.0686156,0.967452 beta-lactamase_39_M115V,beta-lactamase_39_115,TEM-1,beta-lactamase_39,P62593,0.967453,NO,115,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.389,-3.055,1.666,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.0495842,0.0034337,0.967453 beta-lactamase_625_V42I,beta-lactamase_625_42,TEM-1,beta-lactamase_625,P62593,0.967453,NO,42,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.564,-2.098,0.534,,0.017,E,B,0.44,-0.51,2.576,,63.99,BHO,-1.042,0.213352,0.00404515,0.967453 kka2_1:2_A56V,kka2_1:2_56,Kka2,kka2_1:2,P00552,0.967453,NO,56,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.083,-2.653,0.57,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.295029,0.00717715,0.967453 beta-lactamase_156_Q203E,beta-lactamase_156_203,TEM-1,beta-lactamase_156,P62593,0.967454,NO,203,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.168,-2.449,0.281,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.111618,0.00631514,0.967454 PSD95pdz3_Q391G,PSD95pdz3_391,PSD95pdz3,PSD95pdz3,P31016,0.967461,NO,391,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-1.699,-3.04,1.341,5.50275,,,,,12.6589,,,,HPH,-1.481,0.0758425,0.000990786,0.967461 beta-lactamase_39_A34G,beta-lactamase_39_34,TEM-1,beta-lactamase_39,P62593,0.967477,NO,34,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.059,-3.469,1.41,,,H,A,0.46,-0.54,13.292,13.292,73.78,AHA,-1.74967,0.0495842,0.00407913,0.967477 beta-lactamase_156_D161N,beta-lactamase_156_161,TEM-1,beta-lactamase_156,P62593,0.967483,NO,161,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.891,-3.293,2.402,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.111618,0.000897697,0.967483 Pab1_V148E,Pab1_148,Pab1,Pab1,P04147,0.967502,NO,148,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.875,-3.439,1.564,,,,,,,,,,PHH,-1.43033,0.175299,0.00179641,0.967502 beta-lactamase_156_L137M,beta-lactamase_156_137,TEM-1,beta-lactamase_156,P62593,0.967509,NO,137,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.03,-2.58,1.55,,,H,A,0.55,-0.38,0.674,,42.31,HHP,-1.58933,0.111618,0.00278599,0.967509 beta-lactamase_39_H94V,beta-lactamase_39_94,TEM-1,beta-lactamase_39,P62593,0.96751,NO,94,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-2.5,-2.751,0.251,,0.776,,B,0.17,1.24,11.583,11.583,77.62,HBH,-1.872,0.0495842,0.00389226,0.96751 beta-lactamase_P165T,beta-lactamase_165,TEM-1,beta-lactamase,P62593,0.967511,NO,165,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.373,-1.281,-0.092,5.33889,0.203,T,A,0.99,-0.31,0.414,,73.78,AOA,-1.359,0.221079,0.00549538,0.967511 kka2_1:1_A25E,kka2_1:1_25,Kka2,kka2_1:1,P00552,0.967515,NO,25,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.496,-1.817,-0.679,,0.427,E,B,0.46,-0.47,6.872,6.872,65.53,HHP,-2.15167,0.520039,0.00595636,0.967515 beta-lactamase_39_I280W,beta-lactamase_39_280,TEM-1,beta-lactamase_39,P62593,0.967521,NO,280,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.0495842,0.0530888,0.967521 beta-lactamase_625_F70N,beta-lactamase_625_70,TEM-1,beta-lactamase_625,P62593,0.967523,NO,70,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.169,-4.034,2.865,,,H,A,0.58,-1.34,1.14,,63.99,PHB,-0.980667,0.213352,0.00193499,0.967523 kka2_1:4_K50R,kka2_1:4_50,Kka2,kka2_1:4,P00552,0.967539,NO,50,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-0.833,-2.445,1.612,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.168804,0.00138626,0.967539 beta-lactamase_2500_E166V,beta-lactamase_2500_166,TEM-1,beta-lactamase_2500,P62593,0.967549,NO,166,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.756,-2.896,1.14,,0.508,G,A,1.04,1.05,2.124,,73.08,OAH,-1.42233,0.361275,0.00512989,0.967549 beta-lactamase_156_G281W,beta-lactamase_156_281,TEM-1,beta-lactamase_156,P62593,0.967558,NO,281,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.111618,0.0406482,0.967558 Pab1_N139H,Pab1_139,Pab1,Pab1,P04147,0.967564,NO,139,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-1.079,-3.822,2.743,,0.062,H,A,,-0.73,,,,APB,-1.09667,0.175299,0.000339145,0.967564 beta-lactamase_0_S241Q,beta-lactamase_0_241,TEM-1,beta-lactamase_0,P62593,0.967571,NO,241,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.0500837,0.00452736,0.967571 beta-lactamase_F13F,beta-lactamase_13,TEM-1,beta-lactamase,P62593,0.967582,NO,13,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-2.394,-2.394,,,,,,,,4.079,,77.62,OHH,-2.382,0.221079,0.0029078,0.967582 beta-lactamase_T198D,beta-lactamase_198,TEM-1,beta-lactamase,P62593,0.967582,NO,198,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.168,-3.544,1.376,4.9209,0.489,,B,0.69,-0.13,0.37,,73.78,HPH,-1.98767,0.221079,0.004311,0.967582 beta-lactamase_0_E46N,beta-lactamase_0_46,TEM-1,beta-lactamase_0,P62593,0.967586,NO,46,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.94,-4.011,2.071,,0.021,E,B,1.04,0.14,30.306,30.306,59.44,HAH,-2.079,0.0500837,0.00427568,0.967586 beta-lactamase_39_L188Q,beta-lactamase_39_188,TEM-1,beta-lactamase_39,P62593,0.967588,NO,188,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.166,-4.055,2.889,,,H,A,0.55,-0.3,2.982,,60.14,PHB,-1.47033,0.0495842,0.00295687,0.967588 beta-lactamase_39_V259N,beta-lactamase_39_259,TEM-1,beta-lactamase_39,P62593,0.967604,NO,259,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.0495842,0.0070773,0.967604 beta-lactamase_39_D231P,beta-lactamase_39_231,TEM-1,beta-lactamase_39,P62593,0.967627,NO,231,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.816,-3.68,2.864,,,E,B,0.75,-1.06,0.462,,65.38,HAB,-0.994,0.0495842,0.00107395,0.967627 beta-lactamase_2500_R273K,beta-lactamase_2500_273,TEM-1,beta-lactamase_2500,P62593,0.967629,NO,273,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.314,-2.204,-0.11,,0.564,H,A,1.2,1.57,19.943,19.943,73.78,ABP,-1.841,0.361275,0.0077952,0.967629 kka2_1:1_R177R,kka2_1:1_177,Kka2,kka2_1:1,P00552,0.967633,NO,177,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.282,-2.282,,,0.521,T,A,1.2,0.16,1.842,,63.64,HBH,-2.36967,0.520039,0.00768224,0.967633 beta-lactamase_156_D252E,beta-lactamase_156_252,TEM-1,beta-lactamase_156,P62593,0.967642,NO,252,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.111618,0.00575769,0.967642 beta-lactamase_2500_E175Y,beta-lactamase_2500_175,TEM-1,beta-lactamase_2500,P62593,0.967651,NO,175,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.336,-4.303,1.967,,0.551,,A,1.04,1.05,5.316,,77.62,AAB,-1.31233,0.361275,0.00482205,0.967651 beta-lactamase_39_L197V,beta-lactamase_39_197,TEM-1,beta-lactamase_39,P62593,0.967655,NO,197,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.853,-2.903,2.05,,0.007,S,B,0.55,0.33,1.559,,60.14,HHP,-1.833,0.0495842,0.00144602,0.967655 beta-lactamase_2500_I206S,beta-lactamase_2500_206,TEM-1,beta-lactamase_2500,P62593,0.967657,NO,206,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-2.429,-3.468,1.039,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.361275,0.00528934,0.967657 gb1_E241N,gb1_241,gb1,gb1,P06654,0.967674,NO,241,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.672,-3.459,1.787,,,,,,,0.344,,11.83,OAP,-1.27933,0.177985,0.00250604,0.967674 gb1_Q258M,gb1_258,gb1,gb1,P06654,0.967674,NO,258,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.095,-4.448,2.353,,,,,,,0.86,,37.28,BPH,-1.88333,0.177985,0.00437595,0.967674 beta-lactamase_T139T,beta-lactamase_139,TEM-1,beta-lactamase,P62593,0.967694,NO,139,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.901,-1.901,,5.69095,0.216,H,A,0.3,0.39,2.256,,77.62,PPH,-2.04667,0.221079,0.00441837,0.967694 beta-lactamase_39_P217W,beta-lactamase_39_217,TEM-1,beta-lactamase_39,P62593,0.967695,NO,217,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-2.062,-5.565,3.503,,0.496,I,A,0.52,-0.33,21.172,21.172,74.48,OOH,-1.64333,0.0495842,0.00463211,0.967695 beta-lactamase_2500_P25W,beta-lactamase_2500_25,TEM-1,beta-lactamase_2500,P62593,0.9677,NO,25,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.526,-5.419,3.893,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.361275,0.00347571,0.9677 kka2_1:4_E142H,kka2_1:4_142,Kka2,kka2_1:4,P00552,0.967707,NO,142,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.221,-3.221,1,,0.471,H,A,1.52,0.85,3.693,,65.53,HAB,-2.08033,0.168804,0.00748883,0.967707 beta-lactamase_39_A268P,beta-lactamase_39_268,TEM-1,beta-lactamase_39,P62593,0.967724,NO,268,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.0495842,0.0102525,0.967724 beta-lactamase_2500_G194M,beta-lactamase_2500_194,TEM-1,beta-lactamase_2500,P62593,0.967732,NO,194,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.396,-4.893,3.497,,0.276,S,b,0.29,0.36,3.593,,67.83,POA,-1.832,0.361275,0.00392163,0.967732 beta-lactamase_156_D231N,beta-lactamase_156_231,TEM-1,beta-lactamase_156,P62593,0.967738,NO,231,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.816,-3.272,2.456,,,E,B,0.75,-1.06,2.66,,65.38,HAB,-0.994,0.111618,0.00107395,0.967738 PSD95pdz3_G351L,PSD95pdz3_351,PSD95pdz3,PSD95pdz3,P31016,0.967741,NO,351,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.008,-3.49,2.482,5.44798,,,,,20.7625,,,,POA,-1.37133,0.0758425,0.000691282,0.967741 Ubiquitin_A28K,Ubiquitin_28,Uba1,Ubiquitin,P0CG48,0.967742,NO,28,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.895,-2.622,0.727,4.73736,0.369,H,A,,-0.11,,,,BHB,-1.47667,0.205827,0.000842053,0.967742 Ubiquitin_A28M,Ubiquitin_28,Uba1,Ubiquitin,P0CG48,0.967742,NO,28,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.895,-4.659,2.764,4.73736,0.369,H,A,,-0.11,,,,BHB,-1.47667,0.205827,0.000842053,0.967742 Ubiquitin_D24N,Ubiquitin_24,Uba1,Ubiquitin,P0CG48,0.967742,NO,24,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,,,,,,,,,,,,,HAP,,0.205827,0.0066591,0.967742 Ubiquitin_D24S,Ubiquitin_24,Uba1,Ubiquitin,P0CG48,0.967742,NO,24,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,,,,,,,,,,,,,HAP,,0.205827,0.0066591,0.967742 Ubiquitin_D24V,Ubiquitin_24,Uba1,Ubiquitin,P0CG48,0.967742,NO,24,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,,,,,,,,,,,,,HAP,,0.205827,0.0066591,0.967742 Ubiquitin_D39C,Ubiquitin_39,Uba1,Ubiquitin,P0CG48,0.967742,NO,39,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.792,-5.118,3.326,5.1607,0.433,G,A,,0.55,,,,OAP,-1.754,0.205827,0.00071409,0.967742 Ubiquitin_D39H,Ubiquitin_39,Uba1,Ubiquitin,P0CG48,0.967742,NO,39,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.792,-3.188,1.396,5.1607,0.433,G,A,,0.55,,,,OAP,-1.754,0.205827,0.00071409,0.967742 Ubiquitin_D39V,Ubiquitin_39,Uba1,Ubiquitin,P0CG48,0.967742,NO,39,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.792,-3.632,1.84,5.1607,0.433,G,A,,0.55,,,,OAP,-1.754,0.205827,0.00071409,0.967742 Ubiquitin_D52Y,Ubiquitin_52,Uba1,Ubiquitin,P0CG48,0.967742,NO,52,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.43,-4.168,2.738,4.75143,0.421,T,A,,0.79,,,,AAO,-1.50267,0.205827,0.000806517,0.967742 Ubiquitin_E16F,Ubiquitin_16,Uba1,Ubiquitin,P0CG48,0.967742,NO,16,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.545,-4.371,2.826,5.07465,0.567,E,B,,0.59,,,,HAH,-1.31367,0.205827,0.000786769,0.967742 Ubiquitin_E16W,Ubiquitin_16,Uba1,Ubiquitin,P0CG48,0.967742,NO,16,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.545,-5.452,3.907,5.07465,0.567,E,B,,0.59,,,,HAH,-1.31367,0.205827,0.000786769,0.967742 Ubiquitin_E16Y,Ubiquitin_16,Uba1,Ubiquitin,P0CG48,0.967742,NO,16,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.545,-4.307,2.762,5.07465,0.567,E,B,,0.59,,,,HAH,-1.31367,0.205827,0.000786769,0.967742 Ubiquitin_E18F,Ubiquitin_18,Uba1,Ubiquitin,P0CG48,0.967742,NO,18,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.696,-4.265,2.569,5.04795,0.545,,B,,0.03,,,,HAO,-1.78733,0.205827,0.000623342,0.967742 Ubiquitin_E34N,Ubiquitin_34,Uba1,Ubiquitin,P0CG48,0.967742,NO,34,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.294,-3.55,2.256,5.02178,0.406,H,A,1.62,0.6,1.295,,35.62,BAO,-1.24933,0.205827,0.000686048,0.967742 Ubiquitin_E34Q,Ubiquitin_34,Uba1,Ubiquitin,P0CG48,0.967742,NO,34,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.294,-2.697,1.403,5.02178,0.406,H,A,1.62,0.6,1.295,,35.62,BAO,-1.24933,0.205827,0.000686048,0.967742 Ubiquitin_E51I,Ubiquitin_51,Uba1,Ubiquitin,P0CG48,0.967742,NO,51,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.534,-4.018,2.484,5.36711,0.545,,B,,0.72,,,,HAA,-1.357,0.205827,0.000868134,0.967742 Ubiquitin_E51M,Ubiquitin_51,Uba1,Ubiquitin,P0CG48,0.967742,NO,51,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.534,-3.203,1.669,5.36711,0.545,,B,,0.72,,,,HAA,-1.357,0.205827,0.000868134,0.967742 Ubiquitin_E64F,Ubiquitin_64,Uba1,Ubiquitin,P0CG48,0.967742,NO,64,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.763,-4.324,2.561,5.084,0.54,T,l,,0.79,,,,BAP,-1.64433,0.205827,0.000817406,0.967742 Ubiquitin_I23C,Ubiquitin_23,Uba1,Ubiquitin,P0CG48,0.967742,NO,23,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.325,-4.727,3.402,4.67534,,H,A,0.01,-0.93,0.515,,52.12,PHA,-1.54033,0.205827,0.000621252,0.967742 Ubiquitin_I3C,Ubiquitin_3,Uba1,Ubiquitin,P0CG48,0.967742,NO,3,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.402,-4.711,3.309,4.80819,,E,B,,-0.78,,,,PHH,-1.54533,0.205827,0.000836911,0.967742 Ubiquitin_K11S,Ubiquitin_11,Uba1,Ubiquitin,P0CG48,0.967742,NO,11,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.354,-3.267,1.913,5.16813,0.401,,B,2.81,0.84,0.335,,25.84,OBP,-1.346,0.205827,0.000535553,0.967742 Ubiquitin_K11T,Ubiquitin_11,Uba1,Ubiquitin,P0CG48,0.967742,NO,11,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.354,-3.47,2.116,5.16813,0.401,,B,2.81,0.84,0.335,,25.84,OBP,-1.346,0.205827,0.000535553,0.967742 Ubiquitin_K27R,Ubiquitin_27,Uba1,Ubiquitin,P0CG48,0.967742,NO,27,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.064,-2.381,1.317,4.77438,0.086,H,A,2.89,-0.74,2.662,,27.01,HBH,-1.42667,0.205827,0.000767556,0.967742 Ubiquitin_K29W,Ubiquitin_29,Uba1,Ubiquitin,P0CG48,0.967742,NO,29,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.471,-5.351,3.88,4.74832,0.355,H,A,,-0.06,,,,HBH,-1.52367,0.205827,0.000900239,0.967742 Ubiquitin_K33A,Ubiquitin_33,Uba1,Ubiquitin,P0CG48,0.967742,NO,33,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.283,-3.149,1.866,5.08526,0.64,H,A,1.82,1.2,1.509,,51.09,ABA,-1.34267,0.205827,0.000712743,0.967742 Ubiquitin_K33I,Ubiquitin_33,Uba1,Ubiquitin,P0CG48,0.967742,NO,33,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.283,-2.739,1.456,5.08526,0.64,H,A,1.82,1.2,1.509,,51.09,ABA,-1.34267,0.205827,0.000712743,0.967742 Ubiquitin_K33T,Ubiquitin_33,Uba1,Ubiquitin,P0CG48,0.967742,NO,33,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.283,-3.492,2.209,5.08526,0.64,H,A,1.82,1.2,1.509,,51.09,ABA,-1.34267,0.205827,0.000712743,0.967742 Ubiquitin_K63H,Ubiquitin_63,Uba1,Ubiquitin,P0CG48,0.967742,NO,63,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.635,-3.152,1.517,5.08297,0.721,T,B,,0.59,,,,PBA,-1.74467,0.205827,0.000607964,0.967742 Ubiquitin_K63L,Ubiquitin_63,Uba1,Ubiquitin,P0CG48,0.967742,NO,63,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.635,-3.594,1.959,5.08297,0.721,T,B,,0.59,,,,PBA,-1.74467,0.205827,0.000607964,0.967742 Ubiquitin_K63T,Ubiquitin_63,Uba1,Ubiquitin,P0CG48,0.967742,NO,63,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.635,-3.507,1.872,5.08297,0.721,T,B,,0.59,,,,PBA,-1.74467,0.205827,0.000607964,0.967742 Ubiquitin_L15Y,Ubiquitin_15,Uba1,Ubiquitin,P0CG48,0.967742,NO,15,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.082,-3.963,2.881,5.14718,0.029,E,B,1.16,-0.53,0.936,,38.69,PHA,-1.40833,0.205827,0.000519738,0.967742 Ubiquitin_L43V,Ubiquitin_43,Uba1,Ubiquitin,P0CG48,0.967742,NO,43,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.269,-2.395,1.126,4.8799,,E,B,1.75,-1.17,10.246,10.246,53.87,BHH,-1.46867,0.205827,0.000572481,0.967742 Ubiquitin_L56C,Ubiquitin_56,Uba1,Ubiquitin,P0CG48,0.967742,NO,56,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.324,-4.743,3.419,4.83362,,T,A,,-0.91,,,,PHP,-1.60067,0.205827,0.000459465,0.967742 Ubiquitin_L56F,Ubiquitin_56,Uba1,Ubiquitin,P0CG48,0.967742,NO,56,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.324,-2.838,1.514,4.83362,,T,A,,-0.91,,,,PHP,-1.60067,0.205827,0.000459465,0.967742 Ubiquitin_N25I,Ubiquitin_25,Uba1,Ubiquitin,P0CG48,0.967742,NO,25,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-1.95,-3.057,1.107,4.76563,0.444,H,A,0.09,0,2.3,,31.09,APH,-1.741,0.205827,0.00071919,0.967742 Ubiquitin_N25S,Ubiquitin_25,Uba1,Ubiquitin,P0CG48,0.967742,NO,25,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-1.95,-2.518,0.568,4.76563,0.444,H,A,0.09,0,2.3,,31.09,APH,-1.741,0.205827,0.00071919,0.967742 Ubiquitin_N60C,Ubiquitin_60,Uba1,Ubiquitin,P0CG48,0.967742,NO,60,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-1.775,-5.096,3.321,5.00332,0.775,T,L,,0.33,,,,HPH,-1.532,0.205827,0.000814061,0.967742 Ubiquitin_N60G,Ubiquitin_60,Uba1,Ubiquitin,P0CG48,0.967742,NO,60,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-1.775,-2.682,0.907,5.00332,0.775,T,L,,0.33,,,,HPH,-1.532,0.205827,0.000814061,0.967742 Ubiquitin_N60R,Ubiquitin_60,Uba1,Ubiquitin,P0CG48,0.967742,NO,60,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-1.775,-2.998,1.223,5.00332,0.775,T,L,,0.33,,,,HPH,-1.532,0.205827,0.000814061,0.967742 Ubiquitin_Q31A,Ubiquitin_31,Uba1,Ubiquitin,P0CG48,0.967742,NO,31,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-1.678,-3.249,1.571,4.5004,0.464,H,A,,0.68,,,,HPA,-1.44467,0.205827,0.000724141,0.967742 Ubiquitin_Q31S,Ubiquitin_31,Uba1,Ubiquitin,P0CG48,0.967742,NO,31,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-1.678,-3.336,1.658,4.5004,0.464,H,A,,0.68,,,,HPA,-1.44467,0.205827,0.000724141,0.967742 Ubiquitin_Q40H,Ubiquitin_40,Uba1,Ubiquitin,P0CG48,0.967742,NO,40,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-1.752,-3.149,1.397,4.7807,0.387,G,A,,0.03,,,,APP,-1.62433,0.205827,0.000619089,0.967742 Ubiquitin_S20W,Ubiquitin_20,Uba1,Ubiquitin,P0CG48,0.967742,NO,20,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.539,-5.426,3.887,5.15339,0.672,T,A,,-0.6,,,,OPA,-1.69467,0.205827,0.000670478,0.967742 Ubiquitin_T14V,Ubiquitin_14,Uba1,Ubiquitin,P0CG48,0.967742,NO,14,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.598,-2.674,1.076,5.10811,0.345,E,B,,-0.37,,,,HPH,-1.41133,0.205827,0.000632754,0.967742 Ubiquitin_T55D,Ubiquitin_55,Uba1,Ubiquitin,P0CG48,0.967742,NO,55,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.599,-3.696,2.097,4.58329,0.173,B,B,,-0.68,,,,BPH,-1.65333,0.205827,0.000525703,0.967742 Ubiquitin_T55G,Ubiquitin_55,Uba1,Ubiquitin,P0CG48,0.967742,NO,55,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.599,-3.502,1.903,4.58329,0.173,B,B,,-0.68,,,,BPH,-1.65333,0.205827,0.000525703,0.967742 Ubiquitin_T66C,Ubiquitin_66,Uba1,Ubiquitin,P0CG48,0.967742,NO,66,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.58,-3.284,1.704,5.02702,0.46,E,B,0.8,-0.81,28.36,28.36,39.71,PPH,-1.51667,0.205827,0.000598414,0.967742 Ubiquitin_V17H,Ubiquitin_17,Uba1,Ubiquitin,P0CG48,0.967742,NO,17,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.314,-4.885,3.571,5.26282,0.017,,B,2.78,-0.77,3.239,,71.82,AHA,-1.51833,0.205827,0.000659638,0.967742 Ubiquitin_V17Q,Ubiquitin_17,Uba1,Ubiquitin,P0CG48,0.967742,NO,17,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.314,-4.186,2.872,5.26282,0.017,,B,2.78,-0.77,3.239,,71.82,AHA,-1.51833,0.205827,0.000659638,0.967742 Ubiquitin_V5I,Ubiquitin_5,Uba1,Ubiquitin,P0CG48,0.967742,NO,5,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.576,-2.249,0.673,4.75677,,E,B,,-0.82,,,,HHB,-1.401,0.205827,0.000796998,0.967742 Ubiquitin_Y59C,Ubiquitin_59,Uba1,Ubiquitin,P0CG48,0.967742,NO,59,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-1.307,-4.956,3.649,5.05599,0.072,G,A,0.43,-0.74,2.566,,24.53,AHP,-1.568,0.205827,0.000775084,0.967742 Ubiquitin_Y59W,Ubiquitin_59,Uba1,Ubiquitin,P0CG48,0.967742,NO,59,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-1.307,-3.01,1.703,5.05599,0.072,G,A,0.43,-0.74,2.566,,24.53,AHP,-1.568,0.205827,0.000775084,0.967742 kka2_1:8_P179S,kka2_1:8_179,Kka2,kka2_1:8,P00552,0.967745,NO,179,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.974,-2.711,1.737,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.100394,0.00298346,0.967745 kka2_1:8_P179S,kka2_1:8_179,Kka2,kka2_1:8,P00552,0.967745,NO,179,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.974,-2.711,1.737,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.100394,0.00298346,0.967745 beta-lactamase_156_I206Y,beta-lactamase_156_206,TEM-1,beta-lactamase_156,P62593,0.967762,NO,206,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-2.429,-4.278,1.849,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.111618,0.00528934,0.967762 PSD95pdz3_L367Y,PSD95pdz3_367,PSD95pdz3,PSD95pdz3,P31016,0.967763,NO,367,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.347,-3.619,2.272,5.47696,,,,,17.0063,,,,AHB,-1.39767,0.0758425,0.000466436,0.967763 beta-lactamase_156_D231W,beta-lactamase_156_231,TEM-1,beta-lactamase_156,P62593,0.967767,NO,231,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.816,-5.545,4.729,,,E,B,0.75,-1.06,2.66,,65.38,HAB,-0.994,0.111618,0.00107395,0.967767 beta-lactamase_156_M153E,beta-lactamase_156_153,TEM-1,beta-lactamase_156,P62593,0.967774,NO,153,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-3.193,-3.818,0.625,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.111618,0.00509109,0.967774 Pab1_D136Q,Pab1_136,Pab1,Pab1,P04147,0.967774,NO,136,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.602,-3.776,2.174,,,,,,,,,,OAH,-1.42367,0.175299,0.00227029,0.967774 Pab1_E174H,Pab1_174,Pab1,Pab1,P04147,0.96778,NO,174,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.422,-4.247,2.825,,0.578,S,A,,0.38,,,,HAA,-1.65133,0.175299,0.00077863,0.96778 beta-lactamase_2500_G90K,beta-lactamase_2500_90,TEM-1,beta-lactamase_2500,P62593,0.967792,NO,90,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-2.091,-3.514,1.423,,0.598,T,A,0.29,0.32,1.2,,77.62,HOB,-1.52633,0.361275,0.00490273,0.967792 beta-lactamase_2500_M127Q,beta-lactamase_2500_127,TEM-1,beta-lactamase_2500,P62593,0.967794,NO,127,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-2.251,-2.96,0.709,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.361275,0.00437927,0.967794 beta-lactamase_39_D231T,beta-lactamase_39_231,TEM-1,beta-lactamase_39,P62593,0.967805,NO,231,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.816,-3.447,2.631,,,E,B,0.75,-1.06,0.462,,65.38,HAB,-0.994,0.0495842,0.00107395,0.967805 Pab1_N139S,Pab1_139,Pab1,Pab1,P04147,0.967805,NO,139,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-1.079,-2.753,1.674,,0.062,H,A,,-0.73,,,,APB,-1.09667,0.175299,0.000339145,0.967805 beta-lactamase_E270L,beta-lactamase_270,TEM-1,beta-lactamase,P62593,0.967816,NO,270,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.723,-3.523,1.8,5.33196,0.422,H,A,0.52,1.15,1.745,,64.34,AAB,-1.70933,0.221079,0.00767762,0.967816 kka2_1:8_A150E,kka2_1:8_150,Kka2,kka2_1:8,P00552,0.967818,NO,150,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.949,-2.676,1.727,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.100394,0.0045009,0.967818 kka2_1:8_A150E,kka2_1:8_150,Kka2,kka2_1:8,P00552,0.967818,NO,150,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.949,-2.676,1.727,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.100394,0.0045009,0.967818 beta-lactamase_39_L146S,beta-lactamase_39_146,TEM-1,beta-lactamase_39,P62593,0.96782,NO,146,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.462,-2.916,1.454,,0.007,H,A,0.55,-0.56,1.953,,64.69,AHP,-1.656,0.0495842,0.00474542,0.96782 PSD95pdz3_S371N,PSD95pdz3_371,PSD95pdz3,PSD95pdz3,P31016,0.967827,NO,371,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.86,-3.129,1.269,5.19744,,,,,17.1117,3.854,,87.71,HPB,-1.598,0.0758425,0.000847873,0.967827 beta-lactamase_156_T198Q,beta-lactamase_156_198,TEM-1,beta-lactamase_156,P62593,0.967828,NO,198,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.168,-2.734,0.566,,0.489,,B,0.22,-0.13,10.771,10.771,73.78,HPH,-1.98767,0.111618,0.004311,0.967828 beta-lactamase_39_D36F,beta-lactamase_39_36,TEM-1,beta-lactamase_39,P62593,0.967855,NO,36,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.732,-4.318,1.586,,0.555,H,A,0.75,1.17,13.689,13.689,77.62,AAP,-1.91167,0.0495842,0.00476483,0.967855 beta-lactamase_V8V,beta-lactamase_8,TEM-1,beta-lactamase,P62593,0.967859,NO,8,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-2.358,-2.358,,,,,,,,0.575,,77.62,BHH,-2.06267,0.221079,0.00226401,0.967859 hsp90_G584F,hsp90_584,hsp90,hsp90,P02829,0.967863,NO,584,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-2.511,-3.22,0,5.20094,0.414,S,b,0.84,0.33,,,,HOH,-3.32733,0.368192,0.000222939,0.967863 beta-lactamase_156_E272M,beta-lactamase_156_272,TEM-1,beta-lactamase_156,P62593,0.967867,NO,272,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.111618,0.00545371,0.967867 kka2_1:8_A13E,kka2_1:8_13,Kka2,kka2_1:8,P00552,0.96789,NO,13,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.248,-2.832,0.584,,0.689,G,A,1.04,0.99,14.966,14.966,92.05,OHH,-1.646,0.100394,0.00784241,0.96789 kka2_1:8_A13E,kka2_1:8_13,Kka2,kka2_1:8,P00552,0.96789,NO,13,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.248,-2.832,0.584,,0.689,G,A,1.04,0.99,14.966,14.966,92.05,OHH,-1.646,0.100394,0.00784241,0.96789 beta-lactamase_M268I,beta-lactamase_268,TEM-1,beta-lactamase,P62593,0.9679,NO,268,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-2.023,-2.553,0.53,5.4797,0.471,H,A,0.09,0.3,1.071,,65.73,PHA,-2.16233,0.221079,0.0102525,0.9679 beta-lactamase_39_K254M,beta-lactamase_39_254,TEM-1,beta-lactamase_39,P62593,0.967907,NO,254,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.0495842,0.00369,0.967907 beta-lactamase_39_E175Y,beta-lactamase_39_175,TEM-1,beta-lactamase_39,P62593,0.967912,NO,175,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.336,-4.303,1.967,,0.551,,A,1.04,1.05,3.676,,77.62,AAB,-1.31233,0.0495842,0.00482205,0.967912 beta-lactamase_2500_N152F,beta-lactamase_2500_152,TEM-1,beta-lactamase_2500,P62593,0.967917,NO,152,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-2.757,-4.363,1.606,,0.863,H,A,0.61,0.92,2.061,,77.62,BPH,-2.97,0.361275,0.00471429,0.967917 beta-lactamase_156_Y262T,beta-lactamase_156_262,TEM-1,beta-lactamase_156,P62593,0.967924,NO,262,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-1.332,-4.271,2.939,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.111618,0.00853516,0.967924 beta-lactamase_39_E210M,beta-lactamase_39_210,TEM-1,beta-lactamase_39,P62593,0.967927,NO,210,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.319,-4.371,2.052,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.0495842,0.00663582,0.967927 beta-lactamase_39_L120G,beta-lactamase_39_120,TEM-1,beta-lactamase_39,P62593,0.96795,NO,120,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.044,-3.788,2.744,,,H,A,0.55,-1.13,22.254,22.254,64.69,AHO,-1.13633,0.0495842,0.00143563,0.96795 beta-lactamase_39_L100D,beta-lactamase_39_100,TEM-1,beta-lactamase_39,P62593,0.967966,NO,100,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.218,-4.132,2.914,,0.343,,B,0.55,0.13,8.311,,63.29,AHH,-1.23467,0.0495842,0.00413885,0.967966 beta-lactamase_K284V,beta-lactamase_284,TEM-1,beta-lactamase,P62593,0.967976,NO,284,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.981,-3.628,1.647,6.30084,0.848,H,A,1.82,0.67,1.931,,77.62,HBB,-1.82133,0.221079,0.0686156,0.967976 kka2_1:8_D127V,kka2_1:8_127,Kka2,kka2_1:8,P00552,0.967981,NO,127,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.364,-3.744,2.38,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.100394,0.00660501,0.967981 kka2_1:8_D127V,kka2_1:8_127,Kka2,kka2_1:8,P00552,0.967981,NO,127,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.364,-3.744,2.38,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.100394,0.00660501,0.967981 Pab1_P135Y,Pab1_135,Pab1,Pab1,P04147,0.968,NO,135,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.457,-4.186,2.729,,,,,,,6.41,,81.8,BOA,-1.53367,0.175299,0.00148028,0.968 kka2_1:1_T125S,kka2_1:1_125,Kka2,kka2_1:1,P00552,0.96802,NO,125,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.622,-2.445,-0.177,,0.791,T,A,0.22,0.33,1.972,,92.05,BPH,-1.56933,0.520039,0.00821755,0.96802 beta-lactamase_156_A148E,beta-lactamase_156_148,TEM-1,beta-lactamase_156,P62593,0.968031,NO,148,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.757,-2.317,0.56,,0.379,H,A,0.46,-0.55,3.551,,72.73,PHH,-1.40167,0.111618,0.00547053,0.968031 beta-lactamase_2500_S221Y,beta-lactamase_2500_221,TEM-1,beta-lactamase_2500,P62593,0.96804,NO,221,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.754,-4.278,2.524,,0.624,H,A,0.27,-0.2,1.971,,74.48,BPH,-1.59967,0.361275,0.0046094,0.96804 beta-lactamase_39_D99V,beta-lactamase_39_99,TEM-1,beta-lactamase_39,P62593,0.968053,NO,99,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.191,-3.648,2.457,,0.402,G,A,0.75,0.36,0.374,,64.69,PAH,-1.794,0.0495842,0.00305446,0.968053 beta-lactamase_L192V,beta-lactamase_192,TEM-1,beta-lactamase,P62593,0.968075,NO,192,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.254,-1.986,0.732,5.68899,0.095,H,A,1.3,0.35,1.756,,60.14,HHP,-1.41833,0.221079,0.00558728,0.968075 beta-lactamase_0_A185W,beta-lactamase_0_185,TEM-1,beta-lactamase_0,P62593,0.968076,NO,185,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.406,-5.387,3.981,,,H,A,0.46,-1.02,1.203,,65.03,HHP,-1.84033,0.0500837,0.00467449,0.968076 beta-lactamase_156_G90F,beta-lactamase_156_90,TEM-1,beta-lactamase_156,P62593,0.968078,NO,90,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-2.091,-4.407,2.316,,0.598,T,A,0.29,0.32,0.319,,77.62,HOB,-1.52633,0.111618,0.00490273,0.968078 beta-lactamase_156_E102M,beta-lactamase_156_102,TEM-1,beta-lactamase_156,P62593,0.968079,NO,102,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.118,-4.799,2.681,,0.722,S,B,1.04,1.82,15.721,15.721,73.08,HAH,-1.581,0.111618,0.00486633,0.968079 beta-lactamase_39_G39Y,beta-lactamase_39_39,TEM-1,beta-lactamase_39,P62593,0.96808,NO,39,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.864,-4.383,2.519,,0.701,T,L,0.29,0.47,1.454,,77.62,HOH,-1.53633,0.0495842,0.00487611,0.96808 beta-lactamase_2500_E195A,beta-lactamase_2500_195,TEM-1,beta-lactamase_2500,P62593,0.96809,NO,195,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.186,-2.778,0.592,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.361275,0.00496565,0.96809 beta-lactamase_2500_K286M,beta-lactamase_2500_286,TEM-1,beta-lactamase_2500,P62593,0.968097,NO,286,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.361275,,0.968097 Pab1_E181H,Pab1_181,Pab1,Pab1,P04147,0.968125,NO,181,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.767,-4.4,2.633,,,,,,,1.395,,73.83,BAH,-1.575,0.175299,0.00107557,0.968125 beta-lactamase_0_T112N,beta-lactamase_0_112,TEM-1,beta-lactamase_0,P62593,0.968126,NO,112,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.186,-2.739,0.553,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.0500837,0.00531334,0.968126 kka2_1:1_E3K,kka2_1:1_3,Kka2,kka2_1:1,P00552,0.968132,NO,3,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.199,-3.312,1.113,,,,,,,3.435,,92.05,HAP,-2.11567,0.520039,0.00267607,0.968132 beta-lactamase_39_L73W,beta-lactamase_39_73,TEM-1,beta-lactamase_39,P62593,0.968149,NO,73,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.507,-5.171,3.664,,,H,A,0.55,-0.64,2.09,,67.83,HHH,-1.487,0.0495842,0.00488983,0.968149 beta-lactamase_2500_L150I,beta-lactamase_2500_150,TEM-1,beta-lactamase_2500,P62593,0.968155,NO,150,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.326,-3.18,1.854,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.361275,0.00463171,0.968155 beta-lactamase_39_D161S,beta-lactamase_39_161,TEM-1,beta-lactamase_39,P62593,0.968166,NO,161,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.891,-2.488,1.597,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.0495842,0.000897697,0.968166 kka2_1:2_T130H,kka2_1:2_130,Kka2,kka2_1:2,P00552,0.968169,NO,130,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.392,-3.566,1.174,,0.561,G,A,0.22,0.77,0.5,,92.05,HPO,-1.62633,0.295029,0.00804204,0.968169 beta-lactamase_39_T193I,beta-lactamase_39_193,TEM-1,beta-lactamase_39,P62593,0.968187,NO,193,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.914,-2.798,0.884,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.0495842,0.00482669,0.968187 beta-lactamase_0_T264N,beta-lactamase_0_264,TEM-1,beta-lactamase_0,P62593,0.968194,NO,264,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.0500837,0.0119399,0.968194 beta-lactamase_39_E169L,beta-lactamase_39_169,TEM-1,beta-lactamase_39,P62593,0.968204,NO,169,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.23,-3.533,2.303,,0.337,,A,1.04,1,15.633,15.633,73.08,PAH,-1.16533,0.0495842,0.00400994,0.968204 beta-lactamase_G85K,beta-lactamase_85,TEM-1,beta-lactamase,P62593,0.96821,NO,85,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.011,-2.219,1.208,5.58951,0.805,T,l,0.23,1.7,1.468,,63.64,HOP,-1.68733,0.221079,0.00252173,0.96821 beta-lactamase_156_E169D,beta-lactamase_156_169,TEM-1,beta-lactamase_156,P62593,0.968233,NO,169,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.23,-3.13,1.9,,0.337,,A,1.04,1,3.516,,73.08,PAH,-1.16533,0.111618,0.00400994,0.968233 beta-lactamase_39_R202F,beta-lactamase_39_202,TEM-1,beta-lactamase_39,P62593,0.968238,NO,202,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.292,-4.334,3.042,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.0495842,0.00321899,0.968238 Pab1_N139A,Pab1_139,Pab1,Pab1,P04147,0.968242,NO,139,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-1.079,-3.12,2.041,,0.062,H,A,,-0.73,,,,APB,-1.09667,0.175299,0.000339145,0.968242 beta-lactamase_0_R159K,beta-lactamase_0_159,TEM-1,beta-lactamase_0,P62593,0.968248,NO,159,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-0.94,-2.865,1.925,,0.316,,B,1.2,-0.55,1.426,,64.34,PBH,-1.011,0.0500837,0.00108472,0.968248 gb1_T242K,gb1_242,gb1,gb1,P06654,0.968263,NO,242,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.245,-3.192,1.947,,,,,,,,,,APP,-1.444,0.177985,0.00243886,0.968263 kka2_1:8_E96L,kka2_1:8_96,Kka2,kka2_1:8,P00552,0.968271,NO,96,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.573,-3.338,0.765,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.100394,0.00369441,0.968271 kka2_1:8_E96L,kka2_1:8_96,Kka2,kka2_1:8,P00552,0.968271,NO,96,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.573,-3.338,0.765,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.100394,0.00369441,0.968271 beta-lactamase_156_E169I,beta-lactamase_156_169,TEM-1,beta-lactamase_156,P62593,0.968281,NO,169,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.23,-3.986,2.756,,0.337,,A,1.04,1,3.516,,73.08,PAH,-1.16533,0.111618,0.00400994,0.968281 beta-lactamase_625_S104T,beta-lactamase_625_104,TEM-1,beta-lactamase_625,P62593,0.968281,NO,104,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.015,-3.098,2.083,,0.04,,b,0.27,0.57,1.76,,63.29,HPO,-1.05267,0.213352,0.00218083,0.968281 beta-lactamase_0_G194W,beta-lactamase_0_194,TEM-1,beta-lactamase_0,P62593,0.968298,NO,194,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.396,-5.42,4.024,,0.276,S,b,0.29,0.36,3.017,,67.83,POA,-1.832,0.0500837,0.00392163,0.968298 beta-lactamase_0_D271F,beta-lactamase_0_271,TEM-1,beta-lactamase_0,P62593,0.968299,NO,271,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.0500837,0.00752082,0.968299 beta-lactamase_0_C75G,beta-lactamase_0_75,TEM-1,beta-lactamase_0,P62593,0.968307,NO,75,C,G,CG,Special,Special,5.07,3.29388,-1.77612,159,121,75,-46,108.5,60.1,-48.4,-1.245,-2.515,1.27,,,H,A,0.46,-0.87,2.256,,50,HOO,-1.24333,0.0500837,0.0034616,0.968307 beta-lactamase_39_R257K,beta-lactamase_39_257,TEM-1,beta-lactamase_39,P62593,0.968319,NO,257,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.0495842,0.00756629,0.968319 beta-lactamase_156_D83I,beta-lactamase_156_83,TEM-1,beta-lactamase_156,P62593,0.968321,NO,83,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.066,-4.081,3.015,,0.354,H,A,0.75,0.22,1.281,,48.95,HAH,-1.34733,0.111618,0.00205968,0.968321 beta-lactamase_39_Y95A,beta-lactamase_39_95,TEM-1,beta-lactamase_39,P62593,0.968323,NO,95,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-1.715,-3.364,1.649,,0.122,,b,0.21,-0.37,2.341,,77.62,BHP,-2.16167,0.0495842,0.00479449,0.968323 Pab1_K164D,Pab1_164,Pab1,Pab1,P04147,0.968341,NO,164,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-2.298,-3.432,1.134,,,,,,,,,,OBP,-1.41767,0.175299,0.00255241,0.968341 beta-lactamase_625_L192Y,beta-lactamase_625_192,TEM-1,beta-lactamase_625,P62593,0.968348,NO,192,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.254,-3.913,2.659,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.213352,0.00558728,0.968348 beta-lactamase_2500_G85D,beta-lactamase_2500_85,TEM-1,beta-lactamase_2500,P62593,0.968356,NO,85,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.011,-2.383,1.372,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.361275,0.00252173,0.968356 kka2_1:8_P128H,kka2_1:8_128,Kka2,kka2_1:8,P00552,0.968361,NO,128,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.922,-4.964,3.042,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.100394,0.00774689,0.968361 kka2_1:8_P128H,kka2_1:8_128,Kka2,kka2_1:8,P00552,0.968361,NO,128,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.922,-4.964,3.042,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.100394,0.00774689,0.968361 beta-lactamase_39_R189D,beta-lactamase_39_189,TEM-1,beta-lactamase_39,P62593,0.968389,NO,189,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.844,-2.871,1.027,,0.278,H,A,1.2,1.01,12.11,12.11,72.73,HBB,-1.668,0.0495842,0.0050699,0.968389 beta-lactamase_39_N98M,beta-lactamase_39_98,TEM-1,beta-lactamase_39,P62593,0.96839,NO,98,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-2.973,-4.74,1.767,,0.963,G,A,0.61,1.35,14.853,14.853,77.62,PPA,-2.07867,0.0495842,0.00505389,0.96839 beta-lactamase_625_K213M,beta-lactamase_625_213,TEM-1,beta-lactamase_625,P62593,0.968392,NO,213,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.81,-4.653,2.843,,0.67,,A,2.34,0.29,3.924,,67.83,ABH,-1.57767,0.213352,0.00610411,0.968392 beta-lactamase_39_L191H,beta-lactamase_39_191,TEM-1,beta-lactamase_39,P62593,0.968397,NO,191,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.087,-4.898,3.811,,,H,A,0.55,0.09,1.372,,63.29,BHH,-1.445,0.0495842,0.00263549,0.968397 beta-lactamase_156_L146V,beta-lactamase_156_146,TEM-1,beta-lactamase_156,P62593,0.968408,NO,146,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.462,-1.839,0.377,,0.007,H,A,0.55,-0.56,1.578,,64.69,AHP,-1.656,0.111618,0.00474542,0.968408 beta-lactamase_0_V259I,beta-lactamase_0_259,TEM-1,beta-lactamase_0,P62593,0.968414,NO,259,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.522,-1.739,0.217,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.0500837,0.0070773,0.968414 Pab1_D151K,Pab1_151,Pab1,Pab1,P04147,0.968414,NO,151,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.399,-1.96,-0.439,,,,,,,,,,OAH,-1.51767,0.175299,0.00228155,0.968414 beta-lactamase_39_E272C,beta-lactamase_39_272,TEM-1,beta-lactamase_39,P62593,0.968415,NO,272,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.127,,,,0.081,H,A,0.43,-0.97,12.983,12.983,63.64,AAB,-1.56333,0.0495842,0.00545371,0.968415 Pab1_D144Y,Pab1_144,Pab1,Pab1,P04147,0.968415,NO,144,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.189,-4.201,3.012,,0.616,H,A,,0.6,,,,HAP,-1.40567,0.175299,0.00121131,0.968415 beta-lactamase_2500_E175T,beta-lactamase_2500_175,TEM-1,beta-lactamase_2500,P62593,0.968418,NO,175,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.336,-3.551,1.215,,0.551,,A,1.04,1.05,5.316,,77.62,AAB,-1.31233,0.361275,0.00482205,0.968418 beta-lactamase_39_H287S,beta-lactamase_39_287,TEM-1,beta-lactamase_39,P62593,0.968419,NO,287,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,,,,,,,,,,,,,BBH,-1.111,0.0495842,,0.968419 kka2_1:8_P45H,kka2_1:8_45,Kka2,kka2_1:8,P00552,0.968433,NO,45,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.774,-4.807,3.033,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.100394,0.00590481,0.968433 kka2_1:8_P45H,kka2_1:8_45,Kka2,kka2_1:8,P00552,0.968433,NO,45,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.774,-4.807,3.033,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.100394,0.00590481,0.968433 beta-lactamase_2500_T198H,beta-lactamase_2500_198,TEM-1,beta-lactamase_2500,P62593,0.968437,NO,198,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.168,-3.211,1.043,,0.489,,B,0.22,-0.13,0.37,,73.78,HPH,-1.98767,0.361275,0.004311,0.968437 Pab1_D184G,Pab1_184,Pab1,Pab1,P04147,0.968437,NO,184,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.5,-3.14,1.64,,,,,,,,,,HAH,-1.50133,0.175299,0.0011931,0.968437 beta-lactamase_2500_K213R,beta-lactamase_2500_213,TEM-1,beta-lactamase_2500,P62593,0.968441,NO,213,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.81,-1.968,0.158,,0.67,,A,2.34,0.29,1.668,,67.83,ABH,-1.57767,0.361275,0.00610411,0.968441 beta-lactamase_39_I229F,beta-lactamase_39_229,TEM-1,beta-lactamase_39,P62593,0.968457,NO,229,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.267,-3.792,2.525,,0.083,E,B,0.48,-0.76,1.114,,50,HHH,-1.58767,0.0495842,0.00477249,0.968457 beta-lactamase_39_N134M,beta-lactamase_39_134,TEM-1,beta-lactamase_39,P62593,0.968467,NO,134,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-0.879,-4.702,3.823,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.0495842,0.000644786,0.968467 beta-lactamase_625_R81M,beta-lactamase_625_81,TEM-1,beta-lactamase_625,P62593,0.96848,NO,81,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.466,-4.579,3.113,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.213352,0.00499763,0.96848 beta-lactamase_625_R92G,beta-lactamase_625_92,TEM-1,beta-lactamase_625,P62593,0.968481,NO,92,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.718,-3.552,1.834,,0.479,E,B,1.2,1.36,3.069,,65.38,BBH,-1.50367,0.213352,0.00429626,0.968481 beta-lactamase_G251R,beta-lactamase_251,TEM-1,beta-lactamase,P62593,0.968486,NO,251,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.907,-3.1,1.193,5.33865,0.506,T,l,0.73,0.17,10.663,,65.38,AOB,-2.06067,0.221079,0.00733416,0.968486 beta-lactamase_2500_A77S,beta-lactamase_2500_77,TEM-1,beta-lactamase_2500,P62593,0.968526,NO,77,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.234,-2.62,1.386,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.361275,0.00282362,0.968526 beta-lactamase_2500_A200I,beta-lactamase_2500_200,TEM-1,beta-lactamase_2500,P62593,0.968528,NO,200,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.878,-3.937,2.059,,0.757,H,A,0.46,-0.19,0.436,,77.62,HHP,-2.001,0.361275,0.0060056,0.968528 beta-lactamase_625_K213Y,beta-lactamase_625_213,TEM-1,beta-lactamase_625,P62593,0.968535,NO,213,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.81,-4.305,2.495,,0.67,,A,2.34,0.29,3.924,,67.83,ABH,-1.57767,0.213352,0.00610411,0.968535 beta-lactamase_2500_S96F,beta-lactamase_2500_96,TEM-1,beta-lactamase_2500,P62593,0.968566,NO,96,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.27,-4.388,2.118,,0.368,,b,0.27,0.39,32.348,32.348,73.78,HPP,-2.019,0.361275,0.00551835,0.968566 beta-lactamase_39_D231V,beta-lactamase_39_231,TEM-1,beta-lactamase_39,P62593,0.968581,NO,231,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.816,-3.751,2.935,,,E,B,0.75,-1.06,0.462,,65.38,HAB,-0.994,0.0495842,0.00107395,0.968581 PSD95pdz3_R368L,PSD95pdz3_368,PSD95pdz3,PSD95pdz3,P31016,0.968581,NO,368,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.582,-3.04,1.458,6.13355,,,,,18.1818,,,,HBP,-1.50033,0.0758425,0.000451517,0.968581 beta-lactamase_156_M115K,beta-lactamase_156_115,TEM-1,beta-lactamase_156,P62593,0.968593,NO,115,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.389,-3.553,2.164,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.111618,0.0034337,0.968593 beta-lactamase_39_D252A,beta-lactamase_39_252,TEM-1,beta-lactamase_39,P62593,0.968602,NO,252,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.0495842,0.00575769,0.968602 beta-lactamase_156_R81G,beta-lactamase_156_81,TEM-1,beta-lactamase_156,P62593,0.968624,NO,81,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.466,-2.66,1.194,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.111618,0.00499763,0.968624 beta-lactamase_39_D161Q,beta-lactamase_39_161,TEM-1,beta-lactamase_39,P62593,0.968649,NO,161,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.891,-3.667,2.776,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.0495842,0.000897697,0.968649 gb1_K239F,gb1_239,gb1,gb1,P06654,0.968655,NO,239,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-3.043,-3.984,0.941,,,,,,,1.326,,45.54,HBO,-2.31467,0.177985,0.00207004,0.968655 beta-lactamase_39_R176K,beta-lactamase_39_176,TEM-1,beta-lactamase_39,P62593,0.968658,NO,176,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-0.863,-2.782,1.919,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.0495842,0.00105554,0.968658 beta-lactamase_39_D271R,beta-lactamase_39_271,TEM-1,beta-lactamase_39,P62593,0.968678,NO,271,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.249,-3.747,2.498,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.0495842,0.00752082,0.968678 beta-lactamase_0_L284G,beta-lactamase_0_284,TEM-1,beta-lactamase_0,P62593,0.968692,NO,284,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.981,,,,0.848,H,A,2.89,0.67,4.544,,77.62,PHH,-1.82133,0.0500837,0.0686156,0.968692 beta-lactamase_39_D252F,beta-lactamase_39_252,TEM-1,beta-lactamase_39,P62593,0.968695,NO,252,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.0495842,0.00575769,0.968695 beta-lactamase_625_K213W,beta-lactamase_625_213,TEM-1,beta-lactamase_625,P62593,0.968698,NO,213,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.81,-5.386,3.576,,0.67,,A,2.34,0.29,3.924,,67.83,ABH,-1.57767,0.213352,0.00610411,0.968698 beta-lactamase_39_A268K,beta-lactamase_39_268,TEM-1,beta-lactamase_39,P62593,0.968709,NO,268,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.0495842,0.0102525,0.968709 beta-lactamase_625_A170C,beta-lactamase_625_170,TEM-1,beta-lactamase_625,P62593,0.96871,NO,170,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.237,-4.736,3.499,,0.126,,L,0.46,-0.35,3.626,,64.69,AHH,-1.63267,0.213352,0.00431903,0.96871 beta-lactamase_0_T269M,beta-lactamase_0_269,TEM-1,beta-lactamase_0,P62593,0.968711,NO,269,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.0500837,0.00950944,0.968711 beta-lactamase_625_E62C,beta-lactamase_625_62,TEM-1,beta-lactamase_625,P62593,0.968715,NO,62,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.193,-5.228,4.035,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.213352,0.00264802,0.968715 PSD95pdz3_A370H,PSD95pdz3_370,PSD95pdz3,PSD95pdz3,P31016,0.968758,NO,370,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.307,-4.362,3.055,5.22304,,,,,17.284,,,,PHP,-1.57967,0.0758425,0.000429106,0.968758 PSD95pdz3_G322R,PSD95pdz3_322,PSD95pdz3,PSD95pdz3,P31016,0.968764,NO,322,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.008,-3.615,2.607,5.24791,,,,,16.3275,,,,POH,-1.24867,0.0758425,0.00105821,0.968764 PSD95pdz3_L353S,PSD95pdz3_353,PSD95pdz3,PSD95pdz3,P31016,0.968764,NO,353,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.347,-3.292,1.945,5.81136,,,,,17.3525,,,,AHB,-1.50533,0.0758425,0.000664742,0.968764 PSD95pdz3_N363V,PSD95pdz3_363,PSD95pdz3,PSD95pdz3,P31016,0.968768,NO,363,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-1.41,-3.435,2.025,5.23349,,,,,20.7037,,,,HPO,-1.29433,0.0758425,0.000524014,0.968768 kka2_1:4_M178G,kka2_1:4_178,Kka2,kka2_1:4,P00552,0.968775,NO,178,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-3.206,-2.978,-0.228,,0.554,.,b,0.55,0.68,9.913,9.913,71.59,BHO,-2.154,0.168804,0.00717253,0.968775 beta-lactamase_0_L38R,beta-lactamase_0_38,TEM-1,beta-lactamase_0,P62593,0.968783,NO,38,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.343,-4.054,2.711,,0.088,H,A,0.55,0.2,13.556,13.556,64.34,PHO,-1.78033,0.0500837,0.00373244,0.968783 beta-lactamase_625_L199N,beta-lactamase_625_199,TEM-1,beta-lactamase_625,P62593,0.968814,NO,199,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-2.942,-3.124,0.182,,0.832,H,A,0.55,0.42,1.552,,77.62,PHH,-2.32933,0.213352,0.0048649,0.968814 beta-lactamase_156_R239M,beta-lactamase_156_239,TEM-1,beta-lactamase_156,P62593,0.968815,NO,239,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.111618,0.00213852,0.968815 beta-lactamase_625_D99K,beta-lactamase_625_99,TEM-1,beta-lactamase_625,P62593,0.968818,NO,99,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.191,-3.447,2.256,,0.402,G,A,0.75,0.36,1.318,,64.69,PAH,-1.794,0.213352,0.00305446,0.968818 beta-lactamase_2500_L49Y,beta-lactamase_2500_49,TEM-1,beta-lactamase_2500,P62593,0.968837,NO,49,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.897,-4.158,2.261,,0.131,T,A,0.55,0.04,6.681,,64.69,AHP,-1.99233,0.361275,0.00401477,0.968837 beta-lactamase_625_S122F,beta-lactamase_625_122,TEM-1,beta-lactamase_625,P62593,0.968837,NO,122,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.406,-3.279,0.873,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.213352,0.00497825,0.968837 beta-lactamase_39_M115T,beta-lactamase_39_115,TEM-1,beta-lactamase_39,P62593,0.968845,NO,115,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.389,-3.522,2.133,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.0495842,0.0034337,0.968845 beta-lactamase_39_D113I,beta-lactamase_39_113,TEM-1,beta-lactamase_39,P62593,0.968851,NO,113,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.829,-4.028,2.199,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.0495842,0.00474112,0.968851 beta-lactamase_625_D252I,beta-lactamase_625_252,TEM-1,beta-lactamase_625,P62593,0.968851,NO,252,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.213352,0.00575769,0.968851 kka2_1:1_S251F,kka2_1:1_251,Kka2,kka2_1:1,P00552,0.968865,NO,251,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.636,-4.475,1.839,,0.712,H,A,0.27,-0.25,1.356,,71.59,APP,-2.09367,0.520039,0.0138916,0.968865 beta-lactamase_39_R118K,beta-lactamase_39_118,TEM-1,beta-lactamase_39,P62593,0.968872,NO,118,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.413,-3.492,1.079,,0.457,H,A,1.2,1.39,3.961,,77.62,HBA,-1.785,0.0495842,0.00538794,0.968872 beta-lactamase_39_E119W,beta-lactamase_39_119,TEM-1,beta-lactamase_39,P62593,0.968874,NO,119,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.412,-5.452,4.04,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.0495842,0.00386966,0.968874 beta-lactamase_2500_H156C,beta-lactamase_2500_156,TEM-1,beta-lactamase_2500,P62593,0.968884,NO,156,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-3.156,-5.208,2.052,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.361275,0.00468596,0.968884 PSD95pdz3_R318P,PSD95pdz3_318,PSD95pdz3,PSD95pdz3,P31016,0.968898,NO,318,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.582,-3.561,1.979,4.94876,,,,,17.5609,,,,BBO,-1.40567,0.0758425,0.00110471,0.968898 kka2_1:4_D33A,kka2_1:4_33,Kka2,kka2_1:4,P00552,0.968902,NO,33,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.186,-2.11,-0.076,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.168804,0.00633568,0.968902 beta-lactamase_39_A222I,beta-lactamase_39_222,TEM-1,beta-lactamase_39,P62593,0.968903,NO,222,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.103,-3.632,1.529,,0.233,H,A,0.46,-0.25,1.448,,77.62,PHH,-1.63733,0.0495842,0.00466094,0.968903 WW_domain_A175I,WW_domain_175,Yap65,WW_domain,P46937,0.968914,NO,175,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.631,-3.715,2.084,6.69537,,,,,,6.257,,83.93,OHO,-1.30033,0.153962,0.00326874,0.968914 beta-lactamase_39_I206E,beta-lactamase_39_206,TEM-1,beta-lactamase_39,P62593,0.968915,NO,206,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-2.429,-2.747,0.318,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.0495842,0.00528934,0.968915 kka2_1:4_D127E,kka2_1:4_127,Kka2,kka2_1:4,P00552,0.96892,NO,127,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.364,-2.659,1.295,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.168804,0.00660501,0.96892 kka2_1:8_A191T,kka2_1:8_191,Kka2,kka2_1:8,P00552,0.968957,NO,191,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.831,-3.288,2.457,,,,b,1.04,-0.94,1.306,,50,AHO,-0.868667,0.100394,0.00338807,0.968957 kka2_1:8_A191T,kka2_1:8_191,Kka2,kka2_1:8,P00552,0.968957,NO,191,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.831,-3.288,2.457,,,,b,1.04,-0.94,1.306,,50,AHO,-0.868667,0.100394,0.00338807,0.968957 beta-lactamase_0_M115I,beta-lactamase_0_115,TEM-1,beta-lactamase_0,P62593,0.968965,NO,115,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.389,-3.258,1.869,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.0500837,0.0034337,0.968965 beta-lactamase_156_D231F,beta-lactamase_156_231,TEM-1,beta-lactamase_156,P62593,0.968973,NO,231,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.816,-4.318,3.502,,,E,B,0.75,-1.06,2.66,,65.38,HAB,-0.994,0.111618,0.00107395,0.968973 beta-lactamase_39_E169P,beta-lactamase_39_169,TEM-1,beta-lactamase_39,P62593,0.968977,NO,169,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.23,-3.768,2.538,,0.337,,A,1.04,1,15.633,15.633,73.08,PAH,-1.16533,0.0495842,0.00400994,0.968977 beta-lactamase_0_E238K,beta-lactamase_0_238,TEM-1,beta-lactamase_0,P62593,0.968987,NO,238,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.0500837,0.00743256,0.968987 beta-lactamase_156_S221K,beta-lactamase_156_221,TEM-1,beta-lactamase_156,P62593,0.968993,NO,221,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.754,-2.447,0.693,,0.624,H,A,0.27,-0.2,17.729,17.729,74.48,BPH,-1.59967,0.111618,0.0046094,0.968993 beta-lactamase_39_D36E,beta-lactamase_39_36,TEM-1,beta-lactamase_39,P62593,0.969015,NO,36,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.732,-2.66,-0.072,,0.555,H,A,0.75,1.17,13.689,13.689,77.62,AAP,-1.91167,0.0495842,0.00476483,0.969015 beta-lactamase_39_E62I,beta-lactamase_39_62,TEM-1,beta-lactamase_39,P62593,0.969032,NO,62,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.193,-4.086,2.893,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.0495842,0.00264802,0.969032 beta-lactamase_39_E119C,beta-lactamase_39_119,TEM-1,beta-lactamase_39,P62593,0.969047,NO,119,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.412,-5.165,3.753,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.0495842,0.00386966,0.969047 beta-lactamase_625_G142E,beta-lactamase_625_142,TEM-1,beta-lactamase_625,P62593,0.969047,NO,142,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.707,-3.628,2.921,,0.034,,p,0.29,-0.64,1.35,,64.69,OOO,-0.834,0.213352,0.00060149,0.969047 kka2_1:8_A119V,kka2_1:8_119,Kka2,kka2_1:8,P00552,0.969048,NO,119,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.073,-2.406,1.333,,0.019,H,A,0.46,-0.57,1.511,,71.59,AHH,-2.34,0.100394,0.00441074,0.969048 kka2_1:8_A119V,kka2_1:8_119,Kka2,kka2_1:8,P00552,0.969048,NO,119,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.073,-2.406,1.333,,0.019,H,A,0.46,-0.57,1.511,,71.59,AHH,-2.34,0.100394,0.00441074,0.969048 E1_Ubiquitin_A46P,E1_Ubiquitin_46,Uba1,E1_Ubiquitin,P0CG63,0.969054,NO,46,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.367,-3.701,2.334,,0.398,T,L,,-0.8,,,,HHO,-1.17167,0.18783,0.004233,0.969054 E1_Ubiquitin_G47K,E1_Ubiquitin_47,Uba1,E1_Ubiquitin,P0CG63,0.969054,NO,47,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.999,-3.341,2.342,,0.057,T,l,,-1.21,,,,HOB,-1.195,0.18783,0.00142261,0.969054 E1_Ubiquitin_Q40L,E1_Ubiquitin_40,Uba1,E1_Ubiquitin,P0CG63,0.969054,NO,40,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-1.48,-3.353,1.873,,0.387,G,A,,0.03,,,,OPP,-1.365,0.18783,0.0037961,0.969054 beta-lactamase_39_V72M,beta-lactamase_39_72,TEM-1,beta-lactamase_39,P62593,0.969059,NO,72,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.658,-4.404,2.746,,,H,A,0.44,-1.03,1.92,,65.73,BHH,-1.32167,0.0495842,0.00501194,0.969059 Pab1_E181N,Pab1_181,Pab1,Pab1,P04147,0.969085,NO,181,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.767,-3.485,1.718,,,,,,,1.395,,73.83,BAH,-1.575,0.175299,0.00107557,0.969085 beta-lactamase_2500_Q203H,beta-lactamase_2500_203,TEM-1,beta-lactamase_2500,P62593,0.969088,NO,203,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.168,-4.663,2.495,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.361275,0.00631514,0.969088 beta-lactamase_0_A225I,beta-lactamase_0_225,TEM-1,beta-lactamase_0,P62593,0.9691,NO,225,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.845,-4.041,2.196,,1,T,B,0.46,-0.38,11.722,11.722,74.48,OHO,-1.39967,0.0500837,0.00465057,0.9691 beta-lactamase_39_E169D,beta-lactamase_39_169,TEM-1,beta-lactamase_39,P62593,0.969101,NO,169,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.23,-3.13,1.9,,0.337,,A,1.04,1,15.633,15.633,73.08,PAH,-1.16533,0.0495842,0.00400994,0.969101 WW_domain_K181L,WW_domain_181,Yap65,WW_domain,P46937,0.969128,NO,181,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.35,-3.048,1.698,5.0864,,,,,,0.176,,15.87,HBP,-1.247,0.153962,0.0033022,0.969128 beta-lactamase_2500_L199N,beta-lactamase_2500_199,TEM-1,beta-lactamase_2500,P62593,0.96913,NO,199,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-2.942,-3.124,0.182,,0.832,H,A,0.55,0.42,15.504,15.504,77.62,PHH,-2.32933,0.361275,0.0048649,0.96913 beta-lactamase_0_H156L,beta-lactamase_0_156,TEM-1,beta-lactamase_0,P62593,0.969131,NO,156,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-3.156,-3.026,-0.13,,0.753,S,A,0.17,-0.6,23.367,23.367,77.62,ABH,-1.932,0.0500837,0.00468596,0.969131 beta-lactamase_625_K213S,beta-lactamase_625_213,TEM-1,beta-lactamase_625,P62593,0.969135,NO,213,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.81,-3.351,1.541,,0.67,,A,2.34,0.29,3.924,,67.83,ABH,-1.57767,0.213352,0.00610411,0.969135 beta-lactamase_39_E35D,beta-lactamase_39_35,TEM-1,beta-lactamase_39,P62593,0.969137,NO,35,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-0.869,-2.219,1.35,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.0495842,0.00174441,0.969137 beta-lactamase_39_Y95S,beta-lactamase_39_95,TEM-1,beta-lactamase_39,P62593,0.969155,NO,95,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-1.715,-3.776,2.061,,0.122,,b,0.21,-0.37,2.341,,77.62,BHP,-2.16167,0.0495842,0.00479449,0.969155 beta-lactamase_0_V42I,beta-lactamase_0_42,TEM-1,beta-lactamase_0,P62593,0.96916,NO,42,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.564,-2.098,0.534,,0.017,E,B,0.44,-0.51,1.659,,63.99,BHO,-1.042,0.0500837,0.00404515,0.96916 beta-lactamase_156_L199Y,beta-lactamase_156_199,TEM-1,beta-lactamase_156,P62593,0.969161,NO,199,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-2.942,-4.431,1.489,,0.832,H,A,0.55,0.42,1.552,,77.62,PHH,-2.32933,0.111618,0.0048649,0.969161 beta-lactamase_39_D252C,beta-lactamase_39_252,TEM-1,beta-lactamase_39,P62593,0.969187,NO,252,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.0495842,0.00575769,0.969187 beta-lactamase_2500_R239F,beta-lactamase_2500_239,TEM-1,beta-lactamase_2500,P62593,0.969191,NO,239,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.361275,0.00213852,0.969191 beta-lactamase_2500_R275M,beta-lactamase_2500_275,TEM-1,beta-lactamase_2500,P62593,0.969192,NO,275,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.361275,0.0141984,0.969192 PSD95pdz3_D357Y,PSD95pdz3_357,PSD95pdz3,PSD95pdz3,P31016,0.969193,NO,357,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.264,-4.069,2.805,5.22306,,,,,10.975,,,,OAP,-1.32367,0.0758425,0.000609015,0.969193 beta-lactamase_156_L167F,beta-lactamase_156_167,TEM-1,beta-lactamase_156,P62593,0.969197,NO,167,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.138,-3.813,2.675,,0.015,G,A,0.55,-0.63,0.4,,64.69,AHP,-1.30767,0.111618,0.00303566,0.969197 beta-lactamase_156_L248M,beta-lactamase_156_248,TEM-1,beta-lactamase_156,P62593,0.969198,NO,248,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.111618,0.00428493,0.969198 beta-lactamase_39_D33I,beta-lactamase_39_33,TEM-1,beta-lactamase_39,P62593,0.969201,NO,33,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.321,-3.065,0.744,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.0495842,0.00435556,0.969201 beta-lactamase_2500_L73M,beta-lactamase_2500_73,TEM-1,beta-lactamase_2500,P62593,0.969202,NO,73,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.507,-2.898,1.391,,,H,A,0.55,-0.64,2.178,,67.83,HHH,-1.487,0.361275,0.00488983,0.969202 beta-lactamase_39_D99T,beta-lactamase_39_99,TEM-1,beta-lactamase_39,P62593,0.969202,NO,99,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.191,-3.531,2.34,,0.402,G,A,0.75,0.36,0.374,,64.69,PAH,-1.794,0.0495842,0.00305446,0.969202 beta-lactamase_0_S80V,beta-lactamase_0_80,TEM-1,beta-lactamase_0,P62593,0.969205,NO,80,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.029,-2.695,0.666,,0.192,H,A,0.27,0.46,12.403,12.403,77.62,HPB,-1.44567,0.0500837,0.00565569,0.969205 beta-lactamase_625_T198I,beta-lactamase_625_198,TEM-1,beta-lactamase_625,P62593,0.969209,NO,198,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.168,-3.831,1.663,,0.489,,B,0.22,-0.13,0.37,,73.78,HPH,-1.98767,0.213352,0.004311,0.969209 kka2_1:8_E96H,kka2_1:8_96,Kka2,kka2_1:8,P00552,0.96921,NO,96,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.573,-4.74,2.167,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.100394,0.00369441,0.96921 kka2_1:8_E96H,kka2_1:8_96,Kka2,kka2_1:8,P00552,0.96921,NO,96,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.573,-4.74,2.167,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.100394,0.00369441,0.96921 beta-lactamase_39_Y262C,beta-lactamase_39_262,TEM-1,beta-lactamase_39,P62593,0.969213,NO,262,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.0495842,0.00853516,0.969213 beta-lactamase_0_T198L,beta-lactamase_0_198,TEM-1,beta-lactamase_0,P62593,0.969216,NO,198,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.168,-3.433,1.265,,0.489,,B,0.22,-0.13,9.874,,73.78,HPH,-1.98767,0.0500837,0.004311,0.969216 beta-lactamase_0_P105I,beta-lactamase_0_105,TEM-1,beta-lactamase_0,P62593,0.969222,NO,105,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.813,-4.008,3.195,,0.226,T,A,0.52,0.8,3.48,,63.29,POH,-1.01533,0.0500837,0.0011981,0.969222 beta-lactamase_2500_E56T,beta-lactamase_2500_56,TEM-1,beta-lactamase_2500,P62593,0.969229,NO,56,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.043,-2.013,-0.03,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.361275,0.00238534,0.969229 beta-lactamase_39_D252E,beta-lactamase_39_252,TEM-1,beta-lactamase_39,P62593,0.96923,NO,252,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.0495842,0.00575769,0.96923 beta-lactamase_156_T112Q,beta-lactamase_156_112,TEM-1,beta-lactamase_156,P62593,0.969233,NO,112,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.186,-3.981,1.795,,0.921,T,A,0.22,1.06,2.87,,73.78,HPA,-1.925,0.111618,0.00531334,0.969233 beta-lactamase_156_D48V,beta-lactamase_156_48,TEM-1,beta-lactamase_156,P62593,0.969236,NO,48,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.101,-3.719,2.618,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.111618,0.0027273,0.969236 beta-lactamase_0_A84G,beta-lactamase_0_84,TEM-1,beta-lactamase_0,P62593,0.969254,NO,84,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.651,-3.358,1.707,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.0500837,0.00503822,0.969254 beta-lactamase_39_L188H,beta-lactamase_39_188,TEM-1,beta-lactamase_39,P62593,0.969256,NO,188,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.166,-4.872,3.706,,,H,A,0.55,-0.3,2.982,,60.14,PHB,-1.47033,0.0495842,0.00295687,0.969256 Pab1_H134G,Pab1_134,Pab1,Pab1,P04147,0.969262,NO,134,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-1.542,-3.134,1.592,,,,,,,,,,HBO,-1.346,0.175299,0.00116356,0.969262 beta-lactamase_156_D252W,beta-lactamase_156_252,TEM-1,beta-lactamase_156,P62593,0.969292,NO,252,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.111618,0.00575769,0.969292 beta-lactamase_A211M,beta-lactamase_211,TEM-1,beta-lactamase,P62593,0.969296,NO,211,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.896,-3.437,1.541,5.54662,0.369,T,A,0.52,-0.69,2.061,,77.62,AHA,-1.94633,0.221079,0.00648183,0.969296 beta-lactamase_A245C,beta-lactamase_245,TEM-1,beta-lactamase,P62593,0.969296,NO,245,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.068,-4.622,3.554,4.78972,,E,B,0.17,-0.92,0.831,,64.69,HHH,-1.58133,0.221079,0.00391032,0.969296 beta-lactamase_A77H,beta-lactamase_77,TEM-1,beta-lactamase,P62593,0.969296,NO,77,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.234,-3.165,1.931,4.75777,0.039,H,A,0.52,-0.56,1.708,,64.34,OHH,-1.294,0.221079,0.00282362,0.969296 beta-lactamase_A84M,beta-lactamase_84,TEM-1,beta-lactamase,P62593,0.969296,NO,84,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.651,-4.707,3.056,5.28927,0.65,T,A,0.52,0.96,1.863,,68.18,AHO,-1.24267,0.221079,0.00503822,0.969296 beta-lactamase_C75A,beta-lactamase_75,TEM-1,beta-lactamase,P62593,0.969296,NO,75,C,A,CA,Special,Hydrophobic,5.07,6,0.93,195,121,89,-32,108.5,88.6,-19.9,-1.245,-1.87,0.625,4.88171,,H,A,0.25,-0.87,0.876,,50,HOO,-1.24333,0.221079,0.0034616,0.969296 beta-lactamase_D113M,beta-lactamase_113,TEM-1,beta-lactamase,P62593,0.969296,NO,113,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.829,-4.826,2.997,6.04499,0.665,T,A,0.23,0.91,21.104,21.104,73.08,PAO,-1.703,0.221079,0.00474112,0.969296 beta-lactamase_D33S,beta-lactamase_33,TEM-1,beta-lactamase,P62593,0.969296,NO,33,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.321,-2.627,0.306,5.05203,0.366,H,A,0.23,0.33,2.032,,77.62,BAH,-2.12133,0.221079,0.00435556,0.969296 beta-lactamase_E102L,beta-lactamase_102,TEM-1,beta-lactamase,P62593,0.969296,NO,102,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.118,-3.618,1.5,6.36157,0.722,S,B,1.5,1.82,1.336,,73.08,HAH,-1.581,0.221079,0.00486633,0.969296 beta-lactamase_E102N,beta-lactamase_102,TEM-1,beta-lactamase,P62593,0.969296,NO,102,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.118,-3.596,1.478,6.36157,0.722,S,B,1.5,1.82,1.336,,73.08,HAH,-1.581,0.221079,0.00486633,0.969296 beta-lactamase_E108N,beta-lactamase_108,TEM-1,beta-lactamase,P62593,0.969296,NO,108,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.46,-3.593,2.133,5.52079,0.572,G,A,0.52,1.87,1.973,,72.73,PAB,-1.437,0.221079,0.00413372,0.969296 beta-lactamase_E108Q,beta-lactamase_108,TEM-1,beta-lactamase,P62593,0.969296,NO,108,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.46,-2.893,1.433,5.52079,0.572,G,A,0.52,1.87,1.973,,72.73,PAB,-1.437,0.221079,0.00413372,0.969296 beta-lactamase_E145F,beta-lactamase_145,TEM-1,beta-lactamase,P62593,0.969296,NO,145,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.357,-4.373,2.016,5.38104,0.545,H,A,0.52,0.79,2.124,,77.62,BAH,-2.069,0.221079,0.00553285,0.969296 beta-lactamase_E169I,beta-lactamase_169,TEM-1,beta-lactamase,P62593,0.969296,NO,169,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.23,-3.986,2.756,5.78896,0.337,,A,0.52,1,1.806,,73.08,PAH,-1.16533,0.221079,0.00400994,0.969296 beta-lactamase_E210A,beta-lactamase_210,TEM-1,beta-lactamase,P62593,0.969296,NO,210,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.319,-3.162,0.843,5.7398,0.476,H,A,0.52,0.75,1.555,,77.62,HAH,-1.88567,0.221079,0.00663582,0.969296 beta-lactamase_E210F,beta-lactamase_210,TEM-1,beta-lactamase,P62593,0.969296,NO,210,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.319,-4.128,1.809,5.7398,0.476,H,A,0.52,0.75,1.555,,77.62,HAH,-1.88567,0.221079,0.00663582,0.969296 beta-lactamase_E210H,beta-lactamase_210,TEM-1,beta-lactamase,P62593,0.969296,NO,210,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.319,-4.778,2.459,5.7398,0.476,H,A,0.52,0.75,1.555,,77.62,HAH,-1.88567,0.221079,0.00663582,0.969296 beta-lactamase_E210M,beta-lactamase_210,TEM-1,beta-lactamase,P62593,0.969296,NO,210,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.319,-4.371,2.052,5.7398,0.476,H,A,0.52,0.75,1.555,,77.62,HAH,-1.88567,0.221079,0.00663582,0.969296 beta-lactamase_E210R,beta-lactamase_210,TEM-1,beta-lactamase,P62593,0.969296,NO,210,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.319,-3.045,0.726,5.7398,0.476,H,A,0.52,0.75,1.555,,77.62,HAH,-1.88567,0.221079,0.00663582,0.969296 beta-lactamase_E210Y,beta-lactamase_210,TEM-1,beta-lactamase,P62593,0.969296,NO,210,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.319,-4.214,1.895,5.7398,0.476,H,A,0.52,0.75,1.555,,77.62,HAH,-1.88567,0.221079,0.00663582,0.969296 beta-lactamase_E46A,beta-lactamase_46,TEM-1,beta-lactamase,P62593,0.969296,NO,46,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.94,-2.586,0.646,5.36461,0.021,E,B,1.51,0.14,0.373,,59.44,HAH,-2.079,0.221079,0.00427568,0.969296 beta-lactamase_F17A,beta-lactamase_17,TEM-1,beta-lactamase,P62593,0.969296,NO,17,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-2.337,-2.467,0.13,,,,,,,2.192,,67.83,HHO,-2.17733,0.221079,0.00216499,0.969296 beta-lactamase_F228M,beta-lactamase_228,TEM-1,beta-lactamase,P62593,0.969296,NO,228,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-2.342,-3.369,1.027,5.33448,0.154,E,B,1.1,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.221079,0.0046669,0.969296 beta-lactamase_F22M,beta-lactamase_22,TEM-1,beta-lactamase,P62593,0.969296,NO,22,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-2.676,-3.208,0.532,,,,,,,1.616,,73.08,HHH,-2.03233,0.221079,0.00262842,0.969296 beta-lactamase_F22R,beta-lactamase_22,TEM-1,beta-lactamase,P62593,0.969296,NO,22,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-2.676,-3.993,1.317,,,,,,,1.616,,73.08,HHH,-2.03233,0.221079,0.00262842,0.969296 beta-lactamase_G194N,beta-lactamase_194,TEM-1,beta-lactamase,P62593,0.969296,NO,194,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.396,-2.573,1.177,5.46622,0.276,S,b,0.77,0.36,3.593,,67.83,POA,-1.832,0.221079,0.00392163,0.969296 beta-lactamase_G251M,beta-lactamase_251,TEM-1,beta-lactamase,P62593,0.969296,NO,251,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.907,-4.782,2.875,5.33865,0.506,T,l,0.73,0.17,10.663,,65.38,AOB,-2.06067,0.221079,0.00733416,0.969296 beta-lactamase_G85Q,beta-lactamase_85,TEM-1,beta-lactamase,P62593,0.969296,NO,85,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.011,-3.928,2.917,5.58951,0.805,T,l,0.23,1.7,1.468,,63.64,HOP,-1.68733,0.221079,0.00252173,0.969296 beta-lactamase_I54A,beta-lactamase_54,TEM-1,beta-lactamase,P62593,0.969296,NO,54,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-2.838,-2.597,-0.241,5.40541,0.669,E,B,0.77,-0.14,3.946,,73.78,BHH,-2.337,0.221079,0.00403589,0.969296 beta-lactamase_K284H,beta-lactamase_284,TEM-1,beta-lactamase,P62593,0.969296,NO,284,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.981,-4.397,2.416,6.30084,0.848,H,A,1.82,0.67,1.931,,77.62,HBB,-1.82133,0.221079,0.0686156,0.969296 beta-lactamase_K284M,beta-lactamase_284,TEM-1,beta-lactamase,P62593,0.969296,NO,284,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.981,-4.614,2.633,6.30084,0.848,H,A,1.82,0.67,1.931,,77.62,HBB,-1.82133,0.221079,0.0686156,0.969296 beta-lactamase_K32V,beta-lactamase_32,TEM-1,beta-lactamase,P62593,0.969296,NO,32,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.984,-3.477,1.493,5.55842,0.563,H,A,1.82,0.34,1.754,,73.08,HBA,-2.04233,0.221079,0.00401283,0.969296 beta-lactamase_L111C,beta-lactamase_111,TEM-1,beta-lactamase,P62593,0.969296,NO,111,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.76,-4.796,3.036,5.8705,0.328,T,A,0.84,0.93,3.836,,64.34,BHP,-1.884,0.221079,0.00480671,0.969296 beta-lactamase_L19D,beta-lactamase_19,TEM-1,beta-lactamase,P62593,0.969296,NO,19,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.682,-3.838,2.156,,,,,,,4.261,,93.01,OHO,-1.894,0.221079,0.00215974,0.969296 beta-lactamase_P172K,beta-lactamase_172,TEM-1,beta-lactamase,P62593,0.969296,NO,172,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.998,-3.522,2.524,5.98941,0.639,T,b,1.1,0.24,2.087,,74.48,HOP,-2.03067,0.221079,0.00312594,0.969296 beta-lactamase_P25M,beta-lactamase_25,TEM-1,beta-lactamase,P62593,0.969296,NO,25,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.526,-4.708,3.182,5.6134,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.221079,0.00347571,0.969296 beta-lactamase_Q204I,beta-lactamase_204,TEM-1,beta-lactamase,P62593,0.969296,NO,204,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-1.382,-3.968,2.586,5.46394,0.204,H,A,0.12,0.09,1.707,,66.08,PPH,-1.49067,0.221079,0.00364106,0.969296 beta-lactamase_Q265W,beta-lactamase_265,TEM-1,beta-lactamase,P62593,0.969296,NO,265,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.58,-5.543,2.963,6.62674,1.116,,A,0.03,1.17,12.514,12.514,69.58,PPH,-1.978,0.221079,0.00811926,0.969296 beta-lactamase_Q274I,beta-lactamase_274,TEM-1,beta-lactamase,P62593,0.969296,NO,274,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.082,-3.488,1.406,5.6671,0.066,H,A,0.11,-0.27,2.354,,64.69,BPH,-1.931,0.221079,0.0110418,0.969296 beta-lactamase_Q274S,beta-lactamase_274,TEM-1,beta-lactamase,P62593,0.969296,NO,274,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.082,-3.3,1.218,5.6671,0.066,H,A,0.11,-0.27,2.354,,64.69,BPH,-1.931,0.221079,0.0110418,0.969296 beta-lactamase_Q4I,beta-lactamase_4,TEM-1,beta-lactamase,P62593,0.969296,NO,4,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,,-3.687,1.123,,,,,,,,,,HPB,,0.221079,0.00316562,0.969296 beta-lactamase_Q86F,beta-lactamase_86,TEM-1,beta-lactamase,P62593,0.969296,NO,86,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.4,-4.354,1.954,5.39897,0.696,S,A,0.12,2.38,2.105,,77.62,OPA,-1.61067,0.221079,0.00450027,0.969296 beta-lactamase_R176M,beta-lactamase_176,TEM-1,beta-lactamase,P62593,0.969296,NO,176,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-0.863,-4.48,3.617,5.61264,0.385,T,B,0.68,-0.63,,,,ABA,-1.38867,0.221079,0.00105554,0.969296 beta-lactamase_R271Q,beta-lactamase_271,TEM-1,beta-lactamase,P62593,0.969296,NO,271,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.249,-2.538,1.289,5.24516,0.085,H,A,1.67,-0.05,0.474,,63.99,ABP,-1.36633,0.221079,0.00752082,0.969296 beta-lactamase_R273Q,beta-lactamase_273,TEM-1,beta-lactamase,P62593,0.969296,NO,273,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.314,-2.364,0.05,,0.564,H,A,1.2,1.57,,,73.78,ABP,-1.841,0.221079,0.0077952,0.969296 beta-lactamase_R273V,beta-lactamase_273,TEM-1,beta-lactamase,P62593,0.969296,NO,273,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.314,-3.626,1.312,,0.564,H,A,1.2,1.57,,,73.78,ABP,-1.841,0.221079,0.0077952,0.969296 beta-lactamase_R41P,beta-lactamase_41,TEM-1,beta-lactamase,P62593,0.969296,NO,41,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-0.942,-3.877,2.935,5.69185,0.321,E,B,0.91,-0.07,4.357,,65.03,HBH,-1.30267,0.221079,0.00123327,0.969296 beta-lactamase_R41Y,beta-lactamase_41,TEM-1,beta-lactamase,P62593,0.969296,NO,41,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-0.942,-4.188,3.246,5.69185,0.321,E,B,0.91,-0.07,4.357,,65.03,HBH,-1.30267,0.221079,0.00123327,0.969296 beta-lactamase_R92M,beta-lactamase_92,TEM-1,beta-lactamase,P62593,0.969296,NO,92,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.718,-3.339,1.621,5.65832,0.479,E,B,0.91,1.36,3.069,,65.38,BBH,-1.50367,0.221079,0.00429626,0.969296 beta-lactamase_R92Y,beta-lactamase_92,TEM-1,beta-lactamase,P62593,0.969296,NO,92,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.718,-4.31,2.592,5.65832,0.479,E,B,0.91,1.36,3.069,,65.38,BBH,-1.50367,0.221079,0.00429626,0.969296 beta-lactamase_S264G,beta-lactamase_264,TEM-1,beta-lactamase,P62593,0.969296,NO,264,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.985,-3.384,1.399,4.67475,0.04,,B,0.25,0.29,34.251,34.251,73.78,OPP,-2.19867,0.221079,0.0119399,0.969296 beta-lactamase_S51Q,beta-lactamase_51,TEM-1,beta-lactamase,P62593,0.969296,NO,51,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.526,-3.91,2.384,5.06164,0.496,T,A,0.25,0.26,1.699,,72.73,PPO,-1.88467,0.221079,0.00504821,0.969296 beta-lactamase_T112C,beta-lactamase_112,TEM-1,beta-lactamase,P62593,0.969296,NO,112,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.186,-5.027,2.841,6.47162,0.921,T,A,0.77,1.06,2.04,,73.78,HPA,-1.925,0.221079,0.00531334,0.969296 beta-lactamase_T116S,beta-lactamase_116,TEM-1,beta-lactamase,P62593,0.969296,NO,116,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.28,-1.932,0.652,4.78335,0.115,E,B,0.69,-0.12,0.343,,67.48,HPH,-1.39967,0.221079,0.00336175,0.969296 beta-lactamase_T138F,beta-lactamase_138,TEM-1,beta-lactamase,P62593,0.969296,NO,138,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.506,-4.444,1.938,5.52585,0.662,H,A,0.3,-0.03,30.445,30.445,73.78,HPP,-1.81233,0.221079,0.00487868,0.969296 beta-lactamase_T138W,beta-lactamase_138,TEM-1,beta-lactamase,P62593,0.969296,NO,138,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.506,-5.551,3.045,5.52585,0.662,H,A,0.3,-0.03,30.445,30.445,73.78,HPP,-1.81233,0.221079,0.00487868,0.969296 beta-lactamase_T139G,beta-lactamase_139,TEM-1,beta-lactamase,P62593,0.969296,NO,139,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.901,-3.413,1.512,5.69095,0.216,H,A,0.3,0.39,2.256,,77.62,PPH,-2.04667,0.221079,0.00441837,0.969296 beta-lactamase_T158T,beta-lactamase_158,TEM-1,beta-lactamase,P62593,0.969296,NO,158,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.116,-1.116,,5.32011,0.036,,B,0.98,-0.85,2.755,,69.58,HPB,-1.269,0.221079,0.00341825,0.969296 beta-lactamase_T193W,beta-lactamase_193,TEM-1,beta-lactamase,P62593,0.969296,NO,193,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.914,-5.211,3.297,5.67952,0.439,H,a,0.3,0.33,1.863,,63.99,HPO,-1.52133,0.221079,0.00482669,0.969296 beta-lactamase_T261L,beta-lactamase_261,TEM-1,beta-lactamase,P62593,0.969296,NO,261,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.88,-1.662,-1.218,5.65483,0.014,E,B,0.53,-0.39,2.449,,77.62,HPP,-1.771,0.221079,0.0123091,0.969296 beta-lactamase_V101S,beta-lactamase_101,TEM-1,beta-lactamase,P62593,0.969296,NO,101,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.295,-3.65,2.355,5.49045,0.342,,B,0.96,0,1.675,,73.08,HHA,-1.54367,0.221079,0.00374492,0.969296 beta-lactamase_V106Q,beta-lactamase_106,TEM-1,beta-lactamase,P62593,0.969296,NO,106,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.218,-4.248,3.03,5.23115,0.258,T,A,0.96,0.24,1.188,,72.73,OHP,-1.04933,0.221079,0.00304168,0.969296 beta-lactamase_X287E,beta-lactamase_287,TEM-1,beta-lactamase,P62593,0.969296,NO,287,X,E,XE,Stop,negativeCharge,5.71,3.22,-2.49,,132.5,147,14,141.9,138.4,-3.5,,,,,,,,,,,,,HXO,-1.111,0.221079,,0.969296 beta-lactamase_X287V,beta-lactamase_287,TEM-1,beta-lactamase,P62593,0.969296,NO,287,X,V,XV,Stop,Hydrophobic,5.71,5.60847,-0.101535,,132.5,117,-15,141.9,140,-1.9,,,,,,,,,,,,,HXO,-1.111,0.221079,,0.969296 beta-lactamase_X287Y,beta-lactamase_287,TEM-1,beta-lactamase,P62593,0.969296,NO,287,X,Y,XY,Stop,Hydrophobic,5.71,5.66,-0.05,,132.5,181,48,141.9,193.6,51.7,,,,,,,,,,,,,HXO,-1.111,0.221079,,0.969296 beta-lactamase_2500_R92H,beta-lactamase_2500_92,TEM-1,beta-lactamase_2500,P62593,0.969297,NO,92,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.718,-4.618,2.9,,0.479,E,B,1.2,1.36,3.069,,65.38,BBH,-1.50367,0.361275,0.00429626,0.969297 beta-lactamase_39_P105W,beta-lactamase_39_105,TEM-1,beta-lactamase_39,P62593,0.969303,NO,105,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.813,-5.545,4.732,,0.226,T,A,0.52,0.8,1.222,,63.29,POH,-1.01533,0.0495842,0.0011981,0.969303 kka2_1:2_E230F,kka2_1:2_230,Kka2,kka2_1:2,P00552,0.969306,NO,230,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.672,-3.006,0.334,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.295029,0.00920051,0.969306 beta-lactamase_625_D99V,beta-lactamase_625_99,TEM-1,beta-lactamase_625,P62593,0.969318,NO,99,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.191,-3.648,2.457,,0.402,G,A,0.75,0.36,1.318,,64.69,PAH,-1.794,0.213352,0.00305446,0.969318 beta-lactamase_625_E62T,beta-lactamase_625_62,TEM-1,beta-lactamase_625,P62593,0.969322,NO,62,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.193,-3.522,2.329,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.213352,0.00264802,0.969322 beta-lactamase_39_V117P,beta-lactamase_39_117,TEM-1,beta-lactamase_39,P62593,0.969325,NO,117,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.53,-4.14,2.61,,,H,A,0.44,-0.34,1.182,,65.03,PHB,-1.741,0.0495842,0.00467906,0.969325 beta-lactamase_625_A148M,beta-lactamase_625_148,TEM-1,beta-lactamase_625,P62593,0.969326,NO,148,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.757,-4.798,3.041,,0.379,H,A,0.46,-0.55,1.359,,72.73,PHH,-1.40167,0.213352,0.00547053,0.969326 beta-lactamase_156_E102W,beta-lactamase_156_102,TEM-1,beta-lactamase_156,P62593,0.969354,NO,102,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.118,-5.479,3.361,,0.722,S,B,1.04,1.82,15.721,15.721,73.08,HAH,-1.581,0.111618,0.00486633,0.969354 beta-lactamase_39_T193E,beta-lactamase_39_193,TEM-1,beta-lactamase_39,P62593,0.969366,NO,193,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.914,-3.756,1.842,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.0495842,0.00482669,0.969366 kka2_1:8_L39W,kka2_1:8_39,Kka2,kka2_1:8,P00552,0.969391,NO,39,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.223,-5.273,4.05,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.100394,0.00493618,0.969391 kka2_1:8_L39W,kka2_1:8_39,Kka2,kka2_1:8,P00552,0.969391,NO,39,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.223,-5.273,4.05,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.100394,0.00493618,0.969391 beta-lactamase_39_W227G,beta-lactamase_39_227,TEM-1,beta-lactamase_39,P62593,0.969392,NO,227,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-0.982,-2.451,1.469,,0.272,,B,0.47,-0.29,1.37,,74.48,OHH,-1.595,0.0495842,0.00226019,0.969392 beta-lactamase_39_K286N,beta-lactamase_39_286,TEM-1,beta-lactamase_39,P62593,0.969394,NO,286,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.0495842,,0.969394 beta-lactamase_39_E175L,beta-lactamase_39_175,TEM-1,beta-lactamase_39,P62593,0.969414,NO,175,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.336,-3.444,1.108,,0.551,,A,1.04,1.05,3.676,,77.62,AAB,-1.31233,0.0495842,0.00482205,0.969414 beta-lactamase_39_H287P,beta-lactamase_39_287,TEM-1,beta-lactamase_39,P62593,0.969422,NO,287,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,,,,,,,,,,,,,BBH,-1.111,0.0495842,,0.969422 beta-lactamase_625_D231N,beta-lactamase_625_231,TEM-1,beta-lactamase_625,P62593,0.969432,NO,231,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.816,-3.272,2.456,,,E,B,0.75,-1.06,1.025,,65.38,HAB,-0.994,0.213352,0.00107395,0.969432 gb1_T270N,gb1_270,gb1,gb1,P06654,0.969435,NO,270,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-3.15,-3.376,0.226,,,,,,,1.326,,45.54,HPH,-1.843,0.177985,0.00223707,0.969435 Pab1_M189Q,Pab1_189,Pab1,Pab1,P04147,0.969448,NO,189,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.406,-3.491,2.085,,0.631,E,b,,2.81,,,,OHH,-1.18,0.175299,0.000278756,0.969448 beta-lactamase_39_L120T,beta-lactamase_39_120,TEM-1,beta-lactamase_39,P62593,0.96946,NO,120,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.044,-3.547,2.503,,,H,A,0.55,-1.13,22.254,22.254,64.69,AHO,-1.13633,0.0495842,0.00143563,0.96946 beta-lactamase_2500_D207W,beta-lactamase_2500_207,TEM-1,beta-lactamase_2500,P62593,0.969463,NO,207,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.064,-5.493,3.429,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.361275,0.00592942,0.969463 beta-lactamase_39_P217M,beta-lactamase_39_217,TEM-1,beta-lactamase_39,P62593,0.969472,NO,217,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-2.062,-4.835,2.773,,0.496,I,A,0.52,-0.33,21.172,21.172,74.48,OOH,-1.64333,0.0495842,0.00463211,0.969472 beta-lactamase_39_Q86A,beta-lactamase_39_86,TEM-1,beta-lactamase_39,P62593,0.969483,NO,86,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.4,-2.601,0.201,,0.696,S,A,0.64,2.38,27.704,27.704,77.62,OPA,-1.61067,0.0495842,0.00450027,0.969483 beta-lactamase_2500_D113Y,beta-lactamase_2500_113,TEM-1,beta-lactamase_2500,P62593,0.969488,NO,113,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.829,-4.441,2.612,,0.665,T,A,0.75,0.91,21.104,21.104,73.08,PAO,-1.703,0.361275,0.00474112,0.969488 beta-lactamase_39_A170H,beta-lactamase_39_170,TEM-1,beta-lactamase_39,P62593,0.96951,NO,170,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.237,-4.694,3.457,,0.126,,L,0.46,-0.35,3.7,,64.69,AHH,-1.63267,0.0495842,0.00431903,0.96951 beta-lactamase_625_D48E,beta-lactamase_625_48,TEM-1,beta-lactamase_625,P62593,0.969513,NO,48,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.101,-2.049,0.948,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.213352,0.0027273,0.969513 beta-lactamase_2500_L284A,beta-lactamase_2500_284,TEM-1,beta-lactamase_2500,P62593,0.969516,NO,284,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.361275,0.0686156,0.969516 beta-lactamase_39_L199Y,beta-lactamase_39_199,TEM-1,beta-lactamase_39,P62593,0.969516,NO,199,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-2.942,-4.431,1.489,,0.832,H,A,0.55,0.42,15.504,15.504,77.62,PHH,-2.32933,0.0495842,0.0048649,0.969516 Pab1_E195P,Pab1_195,Pab1,Pab1,P04147,0.969518,NO,195,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.2,-3.525,2.325,,,,,,,,,,PAH,-1.72467,0.175299,0.000620107,0.969518 beta-lactamase_625_K144Y,beta-lactamase_625_144,TEM-1,beta-lactamase_625,P62593,0.969521,NO,144,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-2.388,-4.321,1.933,,0.863,H,A,2.34,1.27,2.313,,77.62,OBA,-1.904,0.213352,0.00481141,0.969521 kka2_1:8_H106Y,kka2_1:8_106,Kka2,kka2_1:8,P00552,0.969535,NO,106,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-3.13,-4.391,1.261,,1.065,,a,0.87,-0.95,15.956,15.956,71.59,PBH,-2.10433,0.100394,0.00730778,0.969535 kka2_1:8_H106Y,kka2_1:8_106,Kka2,kka2_1:8,P00552,0.969535,NO,106,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-3.13,-4.391,1.261,,1.065,,a,0.87,-0.95,15.956,15.956,71.59,PBH,-2.10433,0.100394,0.00730778,0.969535 beta-lactamase_0_N173V,beta-lactamase_0_173,TEM-1,beta-lactamase_0,P62593,0.96954,NO,173,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-2.663,-3.738,1.075,,1.044,T,l,0.61,1.25,1.133,,77.62,OPA,-1.46633,0.0500837,0.0033769,0.96954 beta-lactamase_0_R220W,beta-lactamase_0_220,TEM-1,beta-lactamase_0,P62593,0.969544,NO,220,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-0.942,-5.348,4.406,,0.295,I,A,1.2,-0.76,21.573,21.573,74.48,HBP,-1.33633,0.0500837,0.00232421,0.969544 PSD95pdz3_A390V,PSD95pdz3_390,PSD95pdz3,PSD95pdz3,P31016,0.969549,NO,390,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.307,-2.76,1.453,5.03823,,,,,12.46,,,,HHP,-1.54467,0.0758425,0.00104603,0.969549 beta-lactamase_39_F70H,beta-lactamase_39_70,TEM-1,beta-lactamase_39,P62593,0.969558,NO,70,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.169,-4.494,3.325,,,H,A,0.58,-1.34,1.14,,63.99,PHB,-0.980667,0.0495842,0.00193499,0.969558 beta-lactamase_39_V31C,beta-lactamase_39_31,TEM-1,beta-lactamase_39,P62593,0.969568,NO,31,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.822,-3.252,1.43,,,H,A,0.44,-0.46,2.885,,73.78,BHB,-2.03767,0.0495842,0.00478065,0.969568 beta-lactamase_39_Q203G,beta-lactamase_39_203,TEM-1,beta-lactamase_39,P62593,0.969571,NO,203,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.168,-2.805,0.637,,0.47,H,A,0.64,-0.38,1.453,,65.38,BPP,-1.614,0.0495842,0.00631514,0.969571 beta-lactamase_625_G52M,beta-lactamase_625_52,TEM-1,beta-lactamase_625,P62593,0.969575,NO,52,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.149,-4.888,3.739,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.213352,0.00340138,0.969575 beta-lactamase_39_A34L,beta-lactamase_39_34,TEM-1,beta-lactamase_39,P62593,0.96958,NO,34,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.059,-2.191,0.132,,,H,A,0.46,-0.54,13.292,13.292,73.78,AHA,-1.74967,0.0495842,0.00407913,0.96958 beta-lactamase_39_Y95V,beta-lactamase_39_95,TEM-1,beta-lactamase_39,P62593,0.969599,NO,95,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-1.715,-2.446,0.731,,0.122,,b,0.21,-0.37,2.341,,77.62,BHP,-2.16167,0.0495842,0.00479449,0.969599 beta-lactamase_39_D99F,beta-lactamase_39_99,TEM-1,beta-lactamase_39,P62593,0.9696,NO,99,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.191,-4.277,3.086,,0.402,G,A,0.75,0.36,0.374,,64.69,PAH,-1.794,0.0495842,0.00305446,0.9696 beta-lactamase_W163R,beta-lactamase_163,TEM-1,beta-lactamase,P62593,0.969638,NO,163,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-1.843,-2.51,0.667,6.2765,0.467,,B,1.22,-0.5,3.642,,63.99,BHA,-1.269,0.221079,0.00418955,0.969638 beta-lactamase_625_K254C,beta-lactamase_625_254,TEM-1,beta-lactamase_625,P62593,0.96965,NO,254,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.213352,0.00369,0.96965 beta-lactamase_39_L111K,beta-lactamase_39_111,TEM-1,beta-lactamase_39,P62593,0.96967,NO,111,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.76,-3.773,2.013,,0.328,T,A,0.55,0.93,4.334,,64.34,BHP,-1.884,0.0495842,0.00480671,0.96967 beta-lactamase_156_G90K,beta-lactamase_156_90,TEM-1,beta-lactamase_156,P62593,0.969672,NO,90,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-2.091,-3.514,1.423,,0.598,T,A,0.29,0.32,0.319,,77.62,HOB,-1.52633,0.111618,0.00490273,0.969672 beta-lactamase_39_Y262T,beta-lactamase_39_262,TEM-1,beta-lactamase_39,P62593,0.969673,NO,262,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-1.332,-4.271,2.939,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.0495842,0.00853516,0.969673 beta-lactamase_39_D83L,beta-lactamase_39_83,TEM-1,beta-lactamase_39,P62593,0.969674,NO,83,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.066,-3.79,2.724,,0.354,H,A,0.75,0.22,0.752,,48.95,HAH,-1.34733,0.0495842,0.00205968,0.969674 beta-lactamase_39_D83S,beta-lactamase_39_83,TEM-1,beta-lactamase_39,P62593,0.969687,NO,83,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.066,-2.542,1.476,,0.354,H,A,0.75,0.22,0.752,,48.95,HAH,-1.34733,0.0495842,0.00205968,0.969687 beta-lactamase_39_D113F,beta-lactamase_39_113,TEM-1,beta-lactamase_39,P62593,0.969689,NO,113,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.829,-4.448,2.619,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.0495842,0.00474112,0.969689 beta-lactamase_2500_G85R,beta-lactamase_2500_85,TEM-1,beta-lactamase_2500,P62593,0.9697,NO,85,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.011,-2.784,1.773,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.361275,0.00252173,0.9697 beta-lactamase_2500_A77N,beta-lactamase_2500_77,TEM-1,beta-lactamase_2500,P62593,0.969705,NO,77,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.234,-3.844,2.61,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.361275,0.00282362,0.969705 beta-lactamase_39_D207V,beta-lactamase_39_207,TEM-1,beta-lactamase_39,P62593,0.969711,NO,207,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.064,-3.771,1.707,,0.409,H,A,0.75,0.12,14.511,14.511,77.62,HAH,-1.77033,0.0495842,0.00592942,0.969711 beta-lactamase_156_A40D,beta-lactamase_156_40,TEM-1,beta-lactamase_156,P62593,0.969716,NO,40,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.402,-3.685,2.283,,0.155,S,B,0.46,0.21,1.357,,73.78,OHB,-1.40267,0.111618,0.00490026,0.969716 beta-lactamase_39_W288N,beta-lactamase_39_288,TEM-1,beta-lactamase_39,P62593,0.969717,NO,288,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,,,,,,,,,,,,,BHO,,0.0495842,,0.969717 beta-lactamase_156_R159I,beta-lactamase_156_159,TEM-1,beta-lactamase_156,P62593,0.969718,NO,159,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-0.94,-4.036,3.096,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.111618,0.00108472,0.969718 beta-lactamase_39_L160E,beta-lactamase_39_160,TEM-1,beta-lactamase_39,P62593,0.969723,NO,160,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.977,-3.906,2.929,,0.022,,B,0.55,-0.6,0.895,,44.41,BHA,-0.936,0.0495842,0.00193775,0.969723 PSD95pdz3_Y392C,PSD95pdz3_392,PSD95pdz3,PSD95pdz3,P31016,0.969724,NO,392,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-1.437,-4.544,3.107,5.20337,,,,,11.725,,,,PHB,-1.51733,0.0758425,0.000935211,0.969724 beta-lactamase_0_D33Y,beta-lactamase_0_33,TEM-1,beta-lactamase_0,P62593,0.969732,NO,33,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.321,-4.331,2.01,,0.366,H,A,0.75,0.33,12.514,12.514,77.62,BAH,-2.12133,0.0500837,0.00435556,0.969732 beta-lactamase_39_V42A,beta-lactamase_39_42,TEM-1,beta-lactamase_39,P62593,0.969734,NO,42,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.564,-2.554,0.99,,0.017,E,B,0.44,-0.51,1.86,,63.99,BHO,-1.042,0.0495842,0.00404515,0.969734 Pab1_S165T,Pab1_165,Pab1,Pab1,P04147,0.969734,NO,165,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.146,-2.789,1.643,,0.12,,a,,0.11,,,,BPB,-1.56867,0.175299,0.000307838,0.969734 beta-lactamase_625_L111E,beta-lactamase_625_111,TEM-1,beta-lactamase_625,P62593,0.969744,NO,111,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.76,-3.773,2.013,,0.328,T,A,0.55,0.93,2.26,,64.34,BHP,-1.884,0.213352,0.00480671,0.969744 beta-lactamase_39_L188S,beta-lactamase_39_188,TEM-1,beta-lactamase_39,P62593,0.969758,NO,188,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.166,-3.587,2.421,,,H,A,0.55,-0.3,2.982,,60.14,PHB,-1.47033,0.0495842,0.00295687,0.969758 beta-lactamase_39_W227A,beta-lactamase_39_227,TEM-1,beta-lactamase_39,P62593,0.969766,NO,227,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-0.982,-3.46,2.478,,0.272,,B,0.47,-0.29,1.37,,74.48,OHH,-1.595,0.0495842,0.00226019,0.969766 kka2_1:8_L103G,kka2_1:8_103,Kka2,kka2_1:8,P00552,0.969775,NO,103,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-2.362,-2.706,0.344,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.100394,0.00574792,0.969775 kka2_1:8_L103G,kka2_1:8_103,Kka2,kka2_1:8,P00552,0.969775,NO,103,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-2.362,-2.706,0.344,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.100394,0.00574792,0.969775 beta-lactamase_39_D207T,beta-lactamase_39_207,TEM-1,beta-lactamase_39,P62593,0.969776,NO,207,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.064,-2.565,0.501,,0.409,H,A,0.75,0.12,14.511,14.511,77.62,HAH,-1.77033,0.0495842,0.00592942,0.969776 kka2_1:4_N200S,kka2_1:4_200,Kka2,kka2_1:4,P00552,0.969777,NO,200,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-2.446,-2.785,0.339,,0.756,T,L,0.61,-0.08,1.746,,64.39,APO,-2.08,0.168804,0.00838549,0.969777 beta-lactamase_0_S266H,beta-lactamase_0_266,TEM-1,beta-lactamase_0,P62593,0.969799,NO,266,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.0500837,0.0140785,0.969799 beta-lactamase_39_V101C,beta-lactamase_39_101,TEM-1,beta-lactamase_39,P62593,0.969805,NO,101,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.295,-4.837,3.542,,0.342,,B,0.44,0,2.96,,73.08,HHA,-1.54367,0.0495842,0.00374492,0.969805 beta-lactamase_Q88Q,beta-lactamase_88,TEM-1,beta-lactamase,P62593,0.969805,NO,88,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.086,-2.086,,5.8056,0.807,,B,0.12,2.03,1.84,,77.62,APH,-1.53433,0.221079,0.00504167,0.969805 beta-lactamase_2500_Q204A,beta-lactamase_2500_204,TEM-1,beta-lactamase_2500,P62593,0.969808,NO,204,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-1.382,-2.589,1.207,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.361275,0.00364106,0.969808 beta-lactamase_39_Y103E,beta-lactamase_39_103,TEM-1,beta-lactamase_39,P62593,0.96981,NO,103,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-1.33,-3.564,2.234,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.0495842,0.00443048,0.96981 beta-lactamase_156_K254H,beta-lactamase_156_254,TEM-1,beta-lactamase_156,P62593,0.969814,NO,254,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.111618,0.00369,0.969814 beta-lactamase_156_P250F,beta-lactamase_156_250,TEM-1,beta-lactamase_156,P62593,0.969819,NO,250,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.111618,0.00550899,0.969819 beta-lactamase_39_L89N,beta-lactamase_39_89,TEM-1,beta-lactamase_39,P62593,0.969837,NO,89,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.096,-4.11,3.014,,0.168,T,A,0.55,0.63,3.233,,64.34,PHO,-1.75767,0.0495842,0.00207068,0.969837 beta-lactamase_0_A246F,beta-lactamase_0_246,TEM-1,beta-lactamase_0,P62593,0.969851,NO,246,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.121,-2.727,0.606,,0.01,E,B,0.46,-1.01,1.201,,73.78,HHH,-1.55633,0.0500837,0.00569458,0.969851 beta-lactamase_39_H110I,beta-lactamase_39_110,TEM-1,beta-lactamase_39,P62593,0.969861,NO,110,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-1.706,-4.048,2.342,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.0495842,0.00441499,0.969861 beta-lactamase_625_H287E,beta-lactamase_625_287,TEM-1,beta-lactamase_625,P62593,0.969872,NO,287,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,,,,,,,,,,,,,BBH,-1.111,0.213352,,0.969872 beta-lactamase_39_L73H,beta-lactamase_39_73,TEM-1,beta-lactamase_39,P62593,0.969881,NO,73,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.507,-4.923,3.416,,,H,A,0.55,-0.64,2.09,,67.83,HHH,-1.487,0.0495842,0.00488983,0.969881 beta-lactamase_2500_E56K,beta-lactamase_2500_56,TEM-1,beta-lactamase_2500,P62593,0.969885,NO,56,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.043,-3.327,1.284,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.361275,0.00238534,0.969885 beta-lactamase_39_T139D,beta-lactamase_39_139,TEM-1,beta-lactamase_39,P62593,0.969888,NO,139,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.901,-3.596,1.695,,0.216,H,A,0.22,0.39,0.421,,77.62,PPH,-2.04667,0.0495842,0.00441837,0.969888 beta-lactamase_39_D161V,beta-lactamase_39_161,TEM-1,beta-lactamase_39,P62593,0.969898,NO,161,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.891,-3.753,2.862,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.0495842,0.000897697,0.969898 beta-lactamase_L146V,beta-lactamase_146,TEM-1,beta-lactamase,P62593,0.969903,NO,146,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.462,-1.839,0.377,5.62483,0.007,H,A,1.3,-0.56,1.953,,64.69,AHP,-1.656,0.221079,0.00474542,0.969903 kka2_1:2_L67M,kka2_1:2_67,Kka2,kka2_1:2,P00552,0.969903,NO,67,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.741,-3.833,3.092,,0.007,H,A,1.59,-0.66,,,,BHP,-1.42867,0.295029,0.00102787,0.969903 beta-lactamase_39_D83R,beta-lactamase_39_83,TEM-1,beta-lactamase_39,P62593,0.969907,NO,83,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.066,-3.889,2.823,,0.354,H,A,0.75,0.22,0.752,,48.95,HAH,-1.34733,0.0495842,0.00205968,0.969907 beta-lactamase_Q88I,beta-lactamase_88,TEM-1,beta-lactamase,P62593,0.969911,NO,88,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.086,-3.166,1.08,5.8056,0.807,,B,0.12,2.03,1.84,,77.62,APH,-1.53433,0.221079,0.00504167,0.969911 beta-lactamase_2500_T269R,beta-lactamase_2500_269,TEM-1,beta-lactamase_2500,P62593,0.969922,NO,269,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.361275,0.00950944,0.969922 beta-lactamase_2500_A77K,beta-lactamase_2500_77,TEM-1,beta-lactamase_2500,P62593,0.969926,NO,77,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.234,-3.628,2.394,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.361275,0.00282362,0.969926 beta-lactamase_2500_K109Y,beta-lactamase_2500_109,TEM-1,beta-lactamase_2500,P62593,0.969931,NO,109,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.734,-4.334,2.6,,0.787,G,A,2.34,2.21,0.998,,72.73,ABB,-1.63333,0.361275,0.00462493,0.969931 Pab1_S147R,Pab1_147,Pab1,Pab1,P04147,0.969938,NO,147,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.267,-3.578,2.311,,0.336,H,A,,0.56,,,,HPH,-1.43033,0.175299,0.000610856,0.969938 beta-lactamase_39_E35L,beta-lactamase_39_35,TEM-1,beta-lactamase_39,P62593,0.969944,NO,35,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-0.869,-3.632,2.763,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.0495842,0.00174441,0.969944 beta-lactamase_625_D33C,beta-lactamase_625_33,TEM-1,beta-lactamase_625,P62593,0.969952,NO,33,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.321,-5.054,2.733,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.213352,0.00435556,0.969952 beta-lactamase_625_M66Q,beta-lactamase_625_66,TEM-1,beta-lactamase_625,P62593,0.969961,NO,66,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.362,-3.949,2.587,,0.013,,A,0.55,-0.7,1.659,,73.08,OHH,-1.49567,0.213352,0.00412876,0.969961 beta-lactamase_39_P65Q,beta-lactamase_39_65,TEM-1,beta-lactamase_39,P62593,0.969964,NO,65,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.894,-3.954,3.06,,0.098,E,B,0.52,-0.62,0.623,,40.56,HOH,-1.03233,0.0495842,0.00152776,0.969964 beta-lactamase_39_D36S,beta-lactamase_39_36,TEM-1,beta-lactamase_39,P62593,0.969992,NO,36,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.732,-2.107,-0.625,,0.555,H,A,0.75,1.17,13.689,13.689,77.62,AAP,-1.91167,0.0495842,0.00476483,0.969992 beta-lactamase_625_D48G,beta-lactamase_625_48,TEM-1,beta-lactamase_625,P62593,0.969993,NO,48,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.101,-3.259,2.158,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.213352,0.0027273,0.969993 beta-lactamase_2500_D113I,beta-lactamase_2500_113,TEM-1,beta-lactamase_2500,P62593,0.970001,NO,113,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.829,-4.028,2.199,,0.665,T,A,0.75,0.91,21.104,21.104,73.08,PAO,-1.703,0.361275,0.00474112,0.970001 beta-lactamase_39_I206W,beta-lactamase_39_206,TEM-1,beta-lactamase_39,P62593,0.970026,NO,206,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-2.429,-5.397,2.968,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.0495842,0.00528934,0.970026 beta-lactamase_0_L223H,beta-lactamase_0_223,TEM-1,beta-lactamase_0,P62593,0.970033,NO,223,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.055,-4.894,3.839,,0.27,,B,0.55,0.09,1.633,,74.48,HHO,-1.35033,0.0500837,0.00372793,0.970033 beta-lactamase_156_M115F,beta-lactamase_156_115,TEM-1,beta-lactamase_156,P62593,0.970035,NO,115,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.389,-2.82,1.431,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.111618,0.0034337,0.970035 beta-lactamase_39_N152G,beta-lactamase_39_152,TEM-1,beta-lactamase_39,P62593,0.970044,NO,152,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-2.757,-2.26,-0.497,,0.863,H,A,0.61,0.92,4.038,,77.62,BPH,-2.97,0.0495842,0.00471429,0.970044 beta-lactamase_2500_E56N,beta-lactamase_2500_56,TEM-1,beta-lactamase_2500,P62593,0.970052,NO,56,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.043,-2.542,0.499,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.361275,0.00238534,0.970052 beta-lactamase_39_A215Y,beta-lactamase_39_215,TEM-1,beta-lactamase_39,P62593,0.970052,NO,215,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.503,-4.339,2.836,,,,a,0.46,-0.93,0.494,,74.48,HHO,-1.42633,0.0495842,0.00544007,0.970052 beta-lactamase_156_A278I,beta-lactamase_156_278,TEM-1,beta-lactamase_156,P62593,0.970061,NO,278,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.348,-3.123,1.775,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.111618,0.0310297,0.970061 beta-lactamase_2500_V101I,beta-lactamase_2500_101,TEM-1,beta-lactamase_2500,P62593,0.970065,NO,101,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.295,-2.207,0.912,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.361275,0.00374492,0.970065 beta-lactamase_39_I45T,beta-lactamase_39_45,TEM-1,beta-lactamase_39,P62593,0.970083,NO,45,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-2.421,-2.537,0.116,,,E,B,0.48,-0.3,2.256,,77.62,HHA,-2.30267,0.0495842,0.00452842,0.970083 beta-lactamase_625_D113V,beta-lactamase_625_113,TEM-1,beta-lactamase_625,P62593,0.970092,NO,113,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.829,-3.01,1.181,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.213352,0.00474112,0.970092 beta-lactamase_625_A222C,beta-lactamase_625_222,TEM-1,beta-lactamase_625,P62593,0.970097,NO,222,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.103,-4.939,2.836,,0.233,H,A,0.46,-0.25,1.448,,77.62,PHH,-1.63733,0.213352,0.00466094,0.970097 beta-lactamase_39_D252G,beta-lactamase_39_252,TEM-1,beta-lactamase_39,P62593,0.97011,NO,252,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.0495842,0.00575769,0.97011 beta-lactamase_Y260L,beta-lactamase_260,TEM-1,beta-lactamase,P62593,0.970125,NO,260,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-1.101,-2.446,1.345,5.50878,,E,B,0.73,-1.04,0.865,,60.49,HHP,-1.83433,0.221079,0.00471757,0.970125 beta-lactamase_156_Q88C,beta-lactamase_156_88,TEM-1,beta-lactamase_156,P62593,0.970132,NO,88,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.086,-5.138,3.052,,0.807,,B,0.64,2.03,0.911,,77.62,APH,-1.53433,0.111618,0.00504167,0.970132 beta-lactamase_M67T,beta-lactamase_67,TEM-1,beta-lactamase,P62593,0.970132,NO,67,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-2.231,-3.488,1.257,4.9618,0.006,G,P,1.07,-0.81,1.463,,65.03,HHP,-1.502,0.221079,0.00409753,0.970132 kka2_1:1_D238E,kka2_1:1_238,Kka2,kka2_1:1,P00552,0.970133,NO,238,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.83,-2.206,-0.624,,0.604,H,A,0.75,-0.33,11.329,11.329,92.05,HAB,-2.633,0.520039,0.0113863,0.970133 beta-lactamase_E87E,beta-lactamase_87,TEM-1,beta-lactamase,P62593,0.970146,NO,87,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.421,-1.421,,5.41929,0.048,,B,0.52,0.92,1.754,,64.69,PAP,-1.969,0.221079,0.00337888,0.970146 beta-lactamase_2500_E279T,beta-lactamase_2500_279,TEM-1,beta-lactamase_2500,P62593,0.970153,NO,279,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.361275,0.0192826,0.970153 beta-lactamase_625_L248W,beta-lactamase_625_248,TEM-1,beta-lactamase_625,P62593,0.97016,NO,248,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.213352,0.00428493,0.97016 beta-lactamase_156_M180P,beta-lactamase_156_180,TEM-1,beta-lactamase_156,P62593,0.970172,NO,180,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-2.795,-2.76,-0.035,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.111618,0.00552048,0.970172 beta-lactamase_39_A40N,beta-lactamase_39_40,TEM-1,beta-lactamase_39,P62593,0.970172,NO,40,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.402,-3.756,2.354,,0.155,S,B,0.46,0.21,0.783,,73.78,OHB,-1.40267,0.0495842,0.00490026,0.970172 PSD95pdz3_Y392D,PSD95pdz3_392,PSD95pdz3,PSD95pdz3,P31016,0.970184,NO,392,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-1.437,-3.6,2.163,5.20337,,,,,11.725,,,,PHB,-1.51733,0.0758425,0.000935211,0.970184 beta-lactamase_625_D83A,beta-lactamase_625_83,TEM-1,beta-lactamase_625,P62593,0.970188,NO,83,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.066,-3.208,2.142,,0.354,H,A,0.75,0.22,0.239,,48.95,HAH,-1.34733,0.213352,0.00205968,0.970188 beta-lactamase_2500_V157R,beta-lactamase_2500_157,TEM-1,beta-lactamase_2500,P62593,0.970192,NO,157,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.751,-3.07,1.319,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.361275,0.00506849,0.970192 PSD95pdz3_R368Q,PSD95pdz3_368,PSD95pdz3,PSD95pdz3,P31016,0.970193,NO,368,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.582,-3.131,1.549,6.13355,,,,,18.1818,,,,HBP,-1.50033,0.0758425,0.000451517,0.970193 gb1_I232M,gb1_232,gb1,gb1,P06654,0.970211,NO,232,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-2.175,-4.157,1.982,,,,,,,0.766,,44.87,HHH,-2.152,0.177985,0.00580459,0.970211 beta-lactamase_2500_E62D,beta-lactamase_2500_62,TEM-1,beta-lactamase_2500,P62593,0.970212,NO,62,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.193,-2.088,0.895,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.361275,0.00264802,0.970212 kka2_1:8_P249Q,kka2_1:8_249,Kka2,kka2_1:8,P00552,0.970219,NO,249,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.867,-4.234,2.367,,0.406,.,B,0.52,-0.01,1.699,,92.05,HOA,-1.66867,0.100394,0.011045,0.970219 kka2_1:8_P249Q,kka2_1:8_249,Kka2,kka2_1:8,P00552,0.970219,NO,249,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.867,-4.234,2.367,,0.406,.,B,0.52,-0.01,1.699,,92.05,HOA,-1.66867,0.100394,0.011045,0.970219 beta-lactamase_2500_E175D,beta-lactamase_2500_175,TEM-1,beta-lactamase_2500,P62593,0.970224,NO,175,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.336,-2.916,0.58,,0.551,,A,1.04,1.05,5.316,,77.62,AAB,-1.31233,0.361275,0.00482205,0.970224 beta-lactamase_0_D174H,beta-lactamase_0_174,TEM-1,beta-lactamase_0,P62593,0.970229,NO,174,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.738,-4.455,3.717,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.0500837,0.00125633,0.970229 beta-lactamase_156_A268N,beta-lactamase_156_268,TEM-1,beta-lactamase_156,P62593,0.970239,NO,268,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.111618,0.0102525,0.970239 beta-lactamase_0_S51M,beta-lactamase_0_51,TEM-1,beta-lactamase_0,P62593,0.970241,NO,51,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.526,-4.705,3.179,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.0500837,0.00504821,0.970241 beta-lactamase_2500_L192V,beta-lactamase_2500_192,TEM-1,beta-lactamase_2500,P62593,0.970242,NO,192,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.254,-1.986,0.732,,0.095,H,A,0.55,0.35,1.902,,60.14,HHP,-1.41833,0.361275,0.00558728,0.970242 beta-lactamase_0_E62Y,beta-lactamase_0_62,TEM-1,beta-lactamase_0,P62593,0.970265,NO,62,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.193,-4.285,3.092,,0.342,S,B,1.04,-0.3,5.784,,73.08,AAB,-1.417,0.0500837,0.00264802,0.970265 beta-lactamase_0_D113G,beta-lactamase_0_113,TEM-1,beta-lactamase_0,P62593,0.970277,NO,113,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.829,-2.42,0.591,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.0500837,0.00474112,0.970277 beta-lactamase_2500_I206Y,beta-lactamase_2500_206,TEM-1,beta-lactamase_2500,P62593,0.970284,NO,206,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-2.429,-4.278,1.849,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.361275,0.00528934,0.970284 beta-lactamase_156_A40C,beta-lactamase_156_40,TEM-1,beta-lactamase_156,P62593,0.97029,NO,40,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.402,-4.779,3.377,,0.155,S,B,0.46,0.21,1.357,,73.78,OHB,-1.40267,0.111618,0.00490026,0.97029 Pab1_K180G,Pab1_180,Pab1,Pab1,P04147,0.970293,NO,180,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.945,-3.331,1.386,,,,,,,,,,HBA,-1.575,0.175299,0.00295933,0.970293 beta-lactamase_156_S266K,beta-lactamase_156_266,TEM-1,beta-lactamase_156,P62593,0.970295,NO,266,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.111618,0.0140785,0.970295 beta-lactamase_L55V,beta-lactamase_55,TEM-1,beta-lactamase,P62593,0.970304,NO,55,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.86,-2.346,0.486,,0.372,E,A,1.07,-0.36,1.423,,63.99,HHA,-2.247,0.221079,0.00403741,0.970304 Pab1_D184H,Pab1_184,Pab1,Pab1,P04147,0.970306,NO,184,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.5,-4.212,2.712,,,,,,,,,,HAH,-1.50133,0.175299,0.0011931,0.970306 beta-lactamase_2500_M67S,beta-lactamase_2500_67,TEM-1,beta-lactamase_2500,P62593,0.970309,NO,67,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-2.231,-2.445,0.214,,0.006,G,P,0.55,-0.81,2.653,,65.03,HHP,-1.502,0.361275,0.00409753,0.970309 beta-lactamase_2500_R239G,beta-lactamase_2500_239,TEM-1,beta-lactamase_2500,P62593,0.970315,NO,239,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-0.819,-3.876,3.057,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.361275,0.00213852,0.970315 kka2_1:1_T51Q,kka2_1:1_51,Kka2,kka2_1:1,P00552,0.970316,NO,51,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.199,-3.313,1.114,,0.05,E,B,0.22,-0.05,3.056,,63.64,BPA,-1.76767,0.520039,0.00628861,0.970316 beta-lactamase_39_V101N,beta-lactamase_39_101,TEM-1,beta-lactamase_39,P62593,0.970324,NO,101,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.295,-4.085,2.79,,0.342,,B,0.44,0,2.96,,73.08,HHA,-1.54367,0.0495842,0.00374492,0.970324 beta-lactamase_39_L28W,beta-lactamase_39_28,TEM-1,beta-lactamase_39,P62593,0.970325,NO,28,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.579,-5.332,3.753,,0.277,H,A,0.55,-0.16,3.262,,93.01,PHH,-2.11333,0.0495842,0.00359321,0.970325 beta-lactamase_39_N168P,beta-lactamase_39_168,TEM-1,beta-lactamase_39,P62593,0.970327,NO,168,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-1.029,-3.858,2.829,,0.113,G,A,0.61,-0.4,0.822,,44.41,HPA,-1.13233,0.0495842,0.00288667,0.970327 beta-lactamase_39_N50I,beta-lactamase_39_50,TEM-1,beta-lactamase_39,P62593,0.97034,NO,50,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-2.979,-3.889,0.91,,0.912,T,A,0.61,1.24,10.736,,77.62,HPP,-2.134,0.0495842,0.0047211,0.97034 beta-lactamase_39_D113C,beta-lactamase_39_113,TEM-1,beta-lactamase_39,P62593,0.97036,NO,113,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.829,-5.156,3.327,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.0495842,0.00474112,0.97036 kka2_1:8_E63A,kka2_1:8_63,Kka2,kka2_1:8,P00552,0.970363,NO,63,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-0.762,-3.106,2.344,,0.043,H,A,1.52,-0.43,,,,AAH,-1.283,0.100394,0.00118399,0.970363 kka2_1:8_E63A,kka2_1:8_63,Kka2,kka2_1:8,P00552,0.970363,NO,63,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-0.762,-3.106,2.344,,0.043,H,A,1.52,-0.43,,,,AAH,-1.283,0.100394,0.00118399,0.970363 beta-lactamase_156_G141N,beta-lactamase_156_141,TEM-1,beta-lactamase_156,P62593,0.970369,NO,141,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.828,-3.472,2.644,,0.575,T,l,0.29,-0.28,0.198,,64.69,HOO,-1.08933,0.111618,0.0012419,0.970369 Pab1_Y143A,Pab1_143,Pab1,Pab1,P04147,0.970382,NO,143,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-1.961,-3.234,1.273,,0.409,H,A,,0.3,,,,HHA,-1.39633,0.175299,0.00160364,0.970382 beta-lactamase_2500_A225C,beta-lactamase_2500_225,TEM-1,beta-lactamase_2500,P62593,0.970394,NO,225,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.845,-5.105,3.26,,1,T,B,0.46,-0.38,0.551,,74.48,OHO,-1.39967,0.361275,0.00465057,0.970394 beta-lactamase_L282C,beta-lactamase_282,TEM-1,beta-lactamase,P62593,0.970395,NO,282,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.586,-4.806,3.22,5.16743,0.007,H,A,1.07,0.34,31.31,31.31,63.99,PHH,-1.82367,0.221079,0.0449821,0.970395 beta-lactamase_2500_E145T,beta-lactamase_2500_145,TEM-1,beta-lactamase_2500,P62593,0.970397,NO,145,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.357,-3.565,1.208,,0.545,H,A,1.04,0.79,2.124,,77.62,BAH,-2.069,0.361275,0.00553285,0.970397 kka2_1:4_Q219C,kka2_1:4_219,Kka2,kka2_1:4,P00552,0.970398,NO,219,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-0.93,-5.139,4.209,,0.088,H,A,0.64,-0.85,1.537,,50,HPA,-1.05167,0.168804,0.00237913,0.970398 beta-lactamase_39_D36K,beta-lactamase_39_36,TEM-1,beta-lactamase_39,P62593,0.9704,NO,36,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.732,-2.543,-0.189,,0.555,H,A,0.75,1.17,13.689,13.689,77.62,AAP,-1.91167,0.0495842,0.00476483,0.9704 gb1_K276Y,gb1_276,gb1,gb1,P06654,0.970405,NO,276,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.456,-4.003,2.547,,,,,,,0.236,,12.72,PBP,-1.65133,0.177985,0.00620493,0.970405 beta-lactamase_F58L,beta-lactamase_58,TEM-1,beta-lactamase,P62593,0.970407,NO,58,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-2.914,-3.474,0.56,5.55634,0.266,E,B,1.33,-0.07,2.467,,77.62,PHB,-2.059,0.221079,0.00523369,0.970407 beta-lactamase_2500_D36C,beta-lactamase_2500_36,TEM-1,beta-lactamase_2500,P62593,0.970417,NO,36,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.732,-5.131,2.399,,0.555,H,A,0.75,1.17,2.26,,77.62,AAP,-1.91167,0.361275,0.00476483,0.970417 Pab1_D184S,Pab1_184,Pab1,Pab1,P04147,0.970429,NO,184,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.5,-3.049,1.549,,,,,,,,,,HAH,-1.50133,0.175299,0.0011931,0.970429 beta-lactamase_2500_H156P,beta-lactamase_2500_156,TEM-1,beta-lactamase_2500,P62593,0.970436,NO,156,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-3.156,-2.552,-0.604,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.361275,0.00468596,0.970436 beta-lactamase_39_Q86M,beta-lactamase_39_86,TEM-1,beta-lactamase_39,P62593,0.970436,NO,86,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.4,-3.46,1.06,,0.696,S,A,0.64,2.38,27.704,27.704,77.62,OPA,-1.61067,0.0495842,0.00450027,0.970436 kka2_1:1_H124T,kka2_1:1_124,Kka2,kka2_1:1,P00552,0.970448,NO,124,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-0.84,-3.675,2.835,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.520039,0.00211296,0.970448 beta-lactamase_156_E119N,beta-lactamase_156_119,TEM-1,beta-lactamase_156,P62593,0.970469,NO,119,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.412,-3.591,2.179,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.111618,0.00386966,0.970469 beta-lactamase_39_N134E,beta-lactamase_39_134,TEM-1,beta-lactamase_39,P62593,0.970471,NO,134,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-0.879,-3.212,2.333,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.0495842,0.000644786,0.970471 beta-lactamase_39_A268R,beta-lactamase_39_268,TEM-1,beta-lactamase_39,P62593,0.970482,NO,268,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.0495842,0.0102525,0.970482 beta-lactamase_2500_R41P,beta-lactamase_2500_41,TEM-1,beta-lactamase_2500,P62593,0.970489,NO,41,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-0.942,-3.877,2.935,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.361275,0.00123327,0.970489 beta-lactamase_39_K109I,beta-lactamase_39_109,TEM-1,beta-lactamase_39,P62593,0.970489,NO,109,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.734,-4.102,2.368,,0.787,G,A,2.34,2.21,7.243,,72.73,ABB,-1.63333,0.0495842,0.00462493,0.970489 beta-lactamase_2500_V42M,beta-lactamase_2500_42,TEM-1,beta-lactamase_2500,P62593,0.970495,NO,42,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.564,-2.813,1.249,,0.017,E,B,0.44,-0.51,1.86,,63.99,BHO,-1.042,0.361275,0.00404515,0.970495 beta-lactamase_I54I,beta-lactamase_54,TEM-1,beta-lactamase,P62593,0.970496,NO,54,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-2.838,-2.838,,5.40541,0.669,E,B,0.77,-0.14,3.946,,73.78,BHH,-2.337,0.221079,0.00403589,0.970496 beta-lactamase_39_L188C,beta-lactamase_39_188,TEM-1,beta-lactamase_39,P62593,0.97052,NO,188,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.166,-4.777,3.611,,,H,A,0.55,-0.3,2.982,,60.14,PHB,-1.47033,0.0495842,0.00295687,0.97052 beta-lactamase_156_H24P,beta-lactamase_156_24,TEM-1,beta-lactamase_156,P62593,0.970523,NO,24,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-2.481,-3.827,1.346,,,,,,,2.708,,93.01,OBO,-2.0035,0.111618,0.00238894,0.970523 beta-lactamase_156_D161G,beta-lactamase_156_161,TEM-1,beta-lactamase_156,P62593,0.97053,NO,161,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.891,-3.177,2.286,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.111618,0.000897697,0.97053 PSD95pdz3_D332I,PSD95pdz3_332,PSD95pdz3,PSD95pdz3,P31016,0.970538,NO,332,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.264,-3.692,2.428,6.09878,,,,,48.762,,,,AAO,-1.22533,0.0758425,0.000937818,0.970538 Pab1_A178L,Pab1_178,Pab1,Pab1,P04147,0.970545,NO,178,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.579,-3.107,1.528,,0.019,H,A,0.64,0.64,2.7,,81.63,OHH,-1.61067,0.175299,0.00160192,0.970545 beta-lactamase_39_N134A,beta-lactamase_39_134,TEM-1,beta-lactamase_39,P62593,0.970554,NO,134,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-0.879,-3.3,2.421,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.0495842,0.000644786,0.970554 beta-lactamase_39_K213P,beta-lactamase_39_213,TEM-1,beta-lactamase_39,P62593,0.970565,NO,213,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.81,-3.901,2.091,,0.67,,A,2.34,0.29,2.648,,67.83,ABH,-1.57767,0.0495842,0.00610411,0.970565 WW_domain_R187F,WW_domain_187,Yap65,WW_domain,P46937,0.970571,NO,187,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.402,-4.132,2.73,5.05189,,,,,,3.431,,78.57,PBH,-1.362,0.153962,0.00171149,0.970571 beta-lactamase_0_G253I,beta-lactamase_0_253,TEM-1,beta-lactamase_0,P62593,0.970574,NO,253,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.0500837,0.00786358,0.970574 PSD95pdz3_R368H,PSD95pdz3_368,PSD95pdz3,PSD95pdz3,P31016,0.97058,NO,368,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.582,-3.912,2.33,6.13355,,,,,18.1818,,,,HBP,-1.50033,0.0758425,0.000451517,0.97058 gb1_I232N,gb1_232,gb1,gb1,P06654,0.970598,NO,232,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-2.175,-3.655,1.48,,,,,,,0.766,,44.87,HHH,-2.152,0.177985,0.00580459,0.970598 beta-lactamase_156_Q204K,beta-lactamase_156_204,TEM-1,beta-lactamase_156,P62593,0.970607,NO,204,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-1.382,-2.218,0.836,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.111618,0.00364106,0.970607 beta-lactamase_39_V101Y,beta-lactamase_39_101,TEM-1,beta-lactamase_39,P62593,0.970615,NO,101,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.295,-4.116,2.821,,0.342,,B,0.44,0,2.96,,73.08,HHA,-1.54367,0.0495842,0.00374492,0.970615 beta-lactamase_39_Q276Y,beta-lactamase_39_276,TEM-1,beta-lactamase_39,P62593,0.970616,NO,276,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.0495842,0.0191712,0.970616 beta-lactamase_2500_P172H,beta-lactamase_2500_172,TEM-1,beta-lactamase_2500,P62593,0.970618,NO,172,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.998,-4.746,3.748,,0.639,T,b,0.52,0.24,4.99,,74.48,HOP,-2.03067,0.361275,0.00312594,0.970618 beta-lactamase_2500_G194N,beta-lactamase_2500_194,TEM-1,beta-lactamase_2500,P62593,0.97062,NO,194,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.396,-2.573,1.177,,0.276,S,b,0.29,0.36,3.593,,67.83,POA,-1.832,0.361275,0.00392163,0.97062 beta-lactamase_2500_M153V,beta-lactamase_2500_153,TEM-1,beta-lactamase_2500,P62593,0.970636,NO,153,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-3.193,-2.524,-0.669,,0.14,T,A,0.55,-0.11,3.409,,77.62,PHO,-2.25767,0.361275,0.00509109,0.970636 beta-lactamase_0_P224S,beta-lactamase_0_224,TEM-1,beta-lactamase_0,P62593,0.970639,NO,224,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.893,-2.58,1.687,,0.383,,B,0.52,-0.3,3.587,,74.48,HOH,-1.26433,0.0500837,0.00189564,0.970639 beta-lactamase_39_N152Q,beta-lactamase_39_152,TEM-1,beta-lactamase_39,P62593,0.970649,NO,152,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-2.757,-2.534,-0.223,,0.863,H,A,0.61,0.92,4.038,,77.62,BPH,-2.97,0.0495842,0.00471429,0.970649 Pab1_D184V,Pab1_184,Pab1,Pab1,P04147,0.970653,NO,184,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.5,-3.511,2.011,,,,,,,,,,HAH,-1.50133,0.175299,0.0011931,0.970653 beta-lactamase_625_A222Q,beta-lactamase_625_222,TEM-1,beta-lactamase_625,P62593,0.970654,NO,222,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.103,-4.105,2.002,,0.233,H,A,0.46,-0.25,1.448,,77.62,PHH,-1.63733,0.213352,0.00466094,0.970654 beta-lactamase_R118K,beta-lactamase_118,TEM-1,beta-lactamase,P62593,0.970654,NO,118,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.413,-3.492,1.079,5.8227,0.457,H,A,0.68,1.39,2.144,,77.62,HBA,-1.785,0.221079,0.00538794,0.970654 PSD95pdz3_V386H,PSD95pdz3_386,PSD95pdz3,PSD95pdz3,P31016,0.970666,NO,386,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.465,-4.587,3.122,5.18836,,,,,17.5429,,,,PHP,-1.463,0.0758425,0.000184509,0.970666 beta-lactamase_I256V,beta-lactamase_256,TEM-1,beta-lactamase,P62593,0.970667,NO,256,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.621,-1.839,0.218,5.3196,,E,B,1,-0.84,1.615,,73.08,BHH,-1.80667,0.221079,0.00710634,0.970667 beta-lactamase_39_I206K,beta-lactamase_39_206,TEM-1,beta-lactamase_39,P62593,0.970673,NO,206,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-2.429,-3.632,1.203,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.0495842,0.00528934,0.970673 hsp90_N588N,hsp90_588,hsp90,hsp90,P02829,0.970688,NO,588,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-3.051,-3.051,,4.61142,0.019,H,A,0.14,0.39,,,,HPH,-3.12167,0.368192,0.000222939,0.970688 beta-lactamase_625_G226W,beta-lactamase_625_226,TEM-1,beta-lactamase_625,P62593,0.970696,NO,226,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.461,-5.464,4.003,,0.701,T,l,0.29,-0.25,3.199,,74.48,HOH,-1.42933,0.213352,0.00665294,0.970696 beta-lactamase_39_A170I,beta-lactamase_39_170,TEM-1,beta-lactamase_39,P62593,0.970698,NO,170,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.237,-3.643,2.406,,0.126,,L,0.46,-0.35,3.7,,64.69,AHH,-1.63267,0.0495842,0.00431903,0.970698 beta-lactamase_625_F228T,beta-lactamase_625_228,TEM-1,beta-lactamase_625,P62593,0.970698,NO,228,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-2.342,-2.522,0.18,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.213352,0.0046669,0.970698 beta-lactamase_2500_M66V,beta-lactamase_2500_66,TEM-1,beta-lactamase_2500,P62593,0.970715,NO,66,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.362,-2.395,1.033,,0.013,,A,0.55,-0.7,0.502,,73.08,OHH,-1.49567,0.361275,0.00412876,0.970715 beta-lactamase_2500_E169H,beta-lactamase_2500_169,TEM-1,beta-lactamase_2500,P62593,0.970716,NO,169,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.23,-4.45,3.22,,0.337,,A,1.04,1,1.806,,73.08,PAH,-1.16533,0.361275,0.00400994,0.970716 beta-lactamase_625_S122W,beta-lactamase_625_122,TEM-1,beta-lactamase_625,P62593,0.970722,NO,122,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.406,-5.469,3.063,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.213352,0.00497825,0.970722 kka2_1:8_W24H,kka2_1:8_24,Kka2,kka2_1:8,P00552,0.97074,NO,24,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-1.779,-4.882,3.103,,0.477,E,B,1.51,-0.21,2.503,,56.06,AHH,-2.24467,0.100394,0.00631564,0.97074 kka2_1:8_W24H,kka2_1:8_24,Kka2,kka2_1:8,P00552,0.97074,NO,24,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-1.779,-4.882,3.103,,0.477,E,B,1.51,-0.21,2.503,,56.06,AHH,-2.24467,0.100394,0.00631564,0.97074 beta-lactamase_I283F,beta-lactamase_283,TEM-1,beta-lactamase,P62593,0.970755,NO,283,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.638,-2.82,1.182,5.4178,0.165,H,A,1.23,0.04,1.576,,69.23,HHB,-1.735,0.221079,0.0429138,0.970755 beta-lactamase_0_G194Y,beta-lactamase_0_194,TEM-1,beta-lactamase_0,P62593,0.970759,NO,194,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.396,-4.427,3.031,,0.276,S,b,0.29,0.36,3.017,,67.83,POA,-1.832,0.0500837,0.00392163,0.970759 gb1_F256H,gb1_256,gb1,gb1,P06654,0.970791,NO,256,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.241,-4.232,2.991,,,,,,,,,,HHB,-2.04767,0.177985,0.00435993,0.970791 beta-lactamase_625_S51K,beta-lactamase_625_51,TEM-1,beta-lactamase_625,P62593,0.970796,NO,51,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.526,-3.459,1.933,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.213352,0.00504821,0.970796 beta-lactamase_0_R220P,beta-lactamase_0_220,TEM-1,beta-lactamase_0,P62593,0.970797,NO,220,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-0.942,-3.877,2.935,,0.295,I,A,1.2,-0.76,21.573,21.573,74.48,HBP,-1.33633,0.0500837,0.00232421,0.970797 beta-lactamase_D113R,beta-lactamase_113,TEM-1,beta-lactamase,P62593,0.9708,NO,113,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.829,-2.854,1.025,6.04499,0.665,T,A,0.23,0.91,21.104,21.104,73.08,PAO,-1.703,0.221079,0.00474112,0.9708 E1_Ubiquitin_H70G,E1_Ubiquitin_70,Uba1,E1_Ubiquitin,P0CG63,0.970822,NO,70,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-1.36,,,,0.05,E,B,0.61,-0.97,,,93.18,HBH,-1.146,0.18783,0.00206914,0.970822 E1_Ubiquitin_K48I,E1_Ubiquitin_48,Uba1,E1_Ubiquitin,P0CG63,0.970822,NO,48,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.219,-3.881,2.662,,0.132,E,B,,-0.28,,,,OBO,-1.109,0.18783,0.00100363,0.970822 E1_Ubiquitin_L71L,E1_Ubiquitin_71,Uba1,E1_Ubiquitin,P0CG63,0.970822,NO,71,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.039,-1.039,,,0.591,E,B,,-0.69,,,,BHB,-1.19433,0.18783,0.00148349,0.970822 E1_Ubiquitin_L73R,E1_Ubiquitin_73,Uba1,E1_Ubiquitin,P0CG63,0.970822,NO,73,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.039,-3.75,2.711,,0.518,,B,1.3,1,,,,BHB,-1.175,0.18783,0.00111236,0.970822 E1_Ubiquitin_R74K,E1_Ubiquitin_74,Uba1,E1_Ubiquitin,P0CG63,0.970822,NO,74,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.302,-1.936,0.634,,0.838,T,A,,3.15,,,,HBO,-1.11333,0.18783,0.00180798,0.970822 beta-lactamase_39_H287A,beta-lactamase_39_287,TEM-1,beta-lactamase_39,P62593,0.970834,NO,287,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,,,,,,,,,,,,,BBH,-1.111,0.0495842,,0.970834 PSD95pdz3_G319I,PSD95pdz3_319,PSD95pdz3,PSD95pdz3,P31016,0.970841,NO,319,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.008,-3.917,2.909,4.95387,,,,,18.8725,,,,BOP,-1.36967,0.0758425,0.00109317,0.970841 beta-lactamase_39_L188A,beta-lactamase_39_188,TEM-1,beta-lactamase_39,P62593,0.970857,NO,188,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.166,-2.542,1.376,,,H,A,0.55,-0.3,2.982,,60.14,PHB,-1.47033,0.0495842,0.00295687,0.970857 beta-lactamase_39_V29Y,beta-lactamase_39_29,TEM-1,beta-lactamase_39,P62593,0.970859,NO,29,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-2.856,-4.329,1.473,,0.733,H,A,0.44,-0.78,1.287,,93.01,HHB,-2.24733,0.0495842,0.00318969,0.970859 beta-lactamase_39_S283T,beta-lactamase_39_283,TEM-1,beta-lactamase_39,P62593,0.970862,NO,283,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.0495842,0.0429138,0.970862 kka2_1:4_L92V,kka2_1:4_92,Kka2,kka2_1:4,P00552,0.970869,NO,92,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.893,-2.208,1.315,,0.007,E,B,0.55,-0.19,1.447,,63.26,HHH,-0.962,0.168804,0.00307177,0.970869 beta-lactamase_156_G76M,beta-lactamase_156_76,TEM-1,beta-lactamase_156,P62593,0.970877,NO,76,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.189,-4.767,3.578,,,H,A,0.29,-0.67,3.059,,67.83,OOH,-1.22267,0.111618,0.00476637,0.970877 beta-lactamase_156_R257T,beta-lactamase_156_257,TEM-1,beta-lactamase_156,P62593,0.970889,NO,257,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.111618,0.00756629,0.970889 beta-lactamase_R7G,beta-lactamase_7,TEM-1,beta-lactamase,P62593,0.970899,NO,7,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.683,-3.486,1.803,,,,,,,2.44,,67.13,HBH,-1.96267,0.221079,0.00211375,0.970899 PSD95pdz3_N381L,PSD95pdz3_381,PSD95pdz3,PSD95pdz3,P31016,0.970915,NO,381,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-1.41,-3.265,1.855,5.66057,,,,,28.2162,,,,BPH,-1.37767,0.0758425,0.000265374,0.970915 kka2_1:2_T73I,kka2_1:2_73,Kka2,kka2_1:2,P00552,0.970937,NO,73,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.51,-3.77,1.26,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.295029,0.00628605,0.970937 beta-lactamase_625_E279D,beta-lactamase_625_279,TEM-1,beta-lactamase_625,P62593,0.970943,NO,279,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.213352,0.0192826,0.970943 beta-lactamase_2500_S283Y,beta-lactamase_2500_283,TEM-1,beta-lactamase_2500,P62593,0.97095,NO,283,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.361275,0.0429138,0.97095 beta-lactamase_L160C,beta-lactamase_160,TEM-1,beta-lactamase,P62593,0.970953,NO,160,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.977,-4.68,3.703,5.32068,0.022,,B,1.75,-0.6,0.895,,44.41,BHA,-0.936,0.221079,0.00193775,0.970953 beta-lactamase_2500_T147S,beta-lactamase_2500_147,TEM-1,beta-lactamase_2500,P62593,0.970961,NO,147,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.149,-2.487,1.338,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.361275,0.00226017,0.970961 beta-lactamase_625_V31C,beta-lactamase_625_31,TEM-1,beta-lactamase_625,P62593,0.970982,NO,31,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.822,-3.252,1.43,,,H,A,0.44,-0.46,2.576,,73.78,BHB,-2.03767,0.213352,0.00478065,0.970982 gb1_E241M,gb1_241,gb1,gb1,P06654,0.970984,NO,241,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.672,-4.397,2.725,,,,,,,0.344,,11.83,OAP,-1.27933,0.177985,0.00250604,0.970984 gb1_K239E,gb1_239,gb1,gb1,P06654,0.970984,NO,239,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-3.043,-3.026,-0.017,,,,,,,1.326,,45.54,HBO,-2.31467,0.177985,0.00207004,0.970984 beta-lactamase_2500_E102I,beta-lactamase_2500_102,TEM-1,beta-lactamase_2500,P62593,0.970995,NO,102,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.118,-4.045,1.927,,0.722,S,B,1.04,1.82,1.336,,73.08,HAH,-1.581,0.361275,0.00486633,0.970995 beta-lactamase_39_S221D,beta-lactamase_39_221,TEM-1,beta-lactamase_39,P62593,0.971009,NO,221,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.754,-3.645,1.891,,0.624,H,A,0.27,-0.2,2.69,,74.48,BPH,-1.59967,0.0495842,0.0046094,0.971009 beta-lactamase_156_G226V,beta-lactamase_156_226,TEM-1,beta-lactamase_156,P62593,0.971019,NO,226,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.461,-3.807,2.346,,0.701,T,l,0.29,-0.25,3.199,,74.48,HOH,-1.42933,0.111618,0.00665294,0.971019 beta-lactamase_0_P60Q,beta-lactamase_0_60,TEM-1,beta-lactamase_0,P62593,0.971024,NO,60,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-2.469,-3.986,1.517,,0.256,T,A,0.52,-0.56,3.653,,77.62,BOA,-1.97633,0.0500837,0.00521318,0.971024 Pab1_Y197F,Pab1_197,Pab1,Pab1,P04147,0.971025,NO,197,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-1.345,-1.694,0.349,,,,,,,0.891,,80.42,HHH,-1.41767,0.175299,0.00302474,0.971025 beta-lactamase_625_D33K,beta-lactamase_625_33,TEM-1,beta-lactamase_625,P62593,0.97103,NO,33,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.321,-3.459,1.138,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.213352,0.00435556,0.97103 WW_domain_K181S,WW_domain_181,Yap65,WW_domain,P46937,0.971038,NO,181,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.35,-3.11,1.76,5.0864,,,,,,0.176,,15.87,HBP,-1.247,0.153962,0.0033022,0.971038 beta-lactamase_39_K144M,beta-lactamase_39_144,TEM-1,beta-lactamase_39,P62593,0.971045,NO,144,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-2.388,-4.736,2.348,,0.863,H,A,2.34,1.27,14.556,14.556,77.62,OBA,-1.904,0.0495842,0.00481141,0.971045 beta-lactamase_156_G243C,beta-lactamase_156_243,TEM-1,beta-lactamase_156,P62593,0.971046,NO,243,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.532,,,,,E,B,0.77,-1.24,2.866,,50,BOH,-1.46867,0.111618,0.00464034,0.971046 beta-lactamase_2500_M180N,beta-lactamase_2500_180,TEM-1,beta-lactamase_2500,P62593,0.971048,NO,180,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-2.795,-3.603,0.808,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.361275,0.00552048,0.971048 beta-lactamase_39_I229N,beta-lactamase_39_229,TEM-1,beta-lactamase_39,P62593,0.971056,NO,229,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.267,-4.128,2.861,,0.083,E,B,0.48,-0.76,1.114,,50,HHH,-1.58767,0.0495842,0.00477249,0.971056 beta-lactamase_G251E,beta-lactamase_251,TEM-1,beta-lactamase,P62593,0.971057,NO,251,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.907,-2.521,0.614,5.33865,0.506,T,l,0.73,0.17,10.663,,65.38,AOB,-2.06067,0.221079,0.00733416,0.971057 PSD95pdz3_N369A,PSD95pdz3_369,PSD95pdz3,PSD95pdz3,P31016,0.971059,NO,369,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-1.572,-2.753,1.181,5.91569,,,,,24.1262,0.44,,87.71,BPH,-1.487,0.0758425,0.000608412,0.971059 Pab1_T159N,Pab1_159,Pab1,Pab1,P04147,0.971065,NO,159,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.445,-2.382,0.937,,,,,,,2.531,,79.03,HPA,-1.19467,0.175299,0.00133849,0.971065 beta-lactamase_39_A170R,beta-lactamase_39_170,TEM-1,beta-lactamase_39,P62593,0.971071,NO,170,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.237,-3.908,2.671,,0.126,,L,0.46,-0.35,3.7,,64.69,AHH,-1.63267,0.0495842,0.00431903,0.971071 beta-lactamase_39_D207E,beta-lactamase_39_207,TEM-1,beta-lactamase_39,P62593,0.971079,NO,207,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.064,-2.615,0.551,,0.409,H,A,0.75,0.12,14.511,14.511,77.62,HAH,-1.77033,0.0495842,0.00592942,0.971079 beta-lactamase_39_E175V,beta-lactamase_39_175,TEM-1,beta-lactamase_39,P62593,0.971084,NO,175,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.336,-2.38,0.044,,0.551,,A,1.04,1.05,3.676,,77.62,AAB,-1.31233,0.0495842,0.00482205,0.971084 beta-lactamase_156_N98C,beta-lactamase_156_98,TEM-1,beta-lactamase_156,P62593,0.971113,NO,98,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-2.973,-5.105,2.132,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.111618,0.00505389,0.971113 beta-lactamase_625_V157D,beta-lactamase_625_157,TEM-1,beta-lactamase_625,P62593,0.971126,NO,157,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.751,-3.908,2.157,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.213352,0.00506849,0.971126 PSD95pdz3_I388M,PSD95pdz3_388,PSD95pdz3,PSD95pdz3,P31016,0.971126,NO,388,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.63,-3.712,2.082,5.17282,,,,,16.0025,,,,PHH,-1.54967,0.0758425,0.000151216,0.971126 beta-lactamase_156_M127A,beta-lactamase_156_127,TEM-1,beta-lactamase_156,P62593,0.971134,NO,127,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-2.251,-3.303,1.052,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.111618,0.00437927,0.971134 beta-lactamase_2500_T147V,beta-lactamase_2500_147,TEM-1,beta-lactamase_2500,P62593,0.971144,NO,147,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.149,-3.22,2.071,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.361275,0.00226017,0.971144 beta-lactamase_2500_P172V,beta-lactamase_2500_172,TEM-1,beta-lactamase_2500,P62593,0.971156,NO,172,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.998,-3.483,2.485,,0.639,T,b,0.52,0.24,4.99,,74.48,HOP,-2.03067,0.361275,0.00312594,0.971156 beta-lactamase_39_V214H,beta-lactamase_39_214,TEM-1,beta-lactamase_39,P62593,0.971156,NO,214,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.299,-4.922,3.623,,0.375,S,A,0.44,-0.44,18.838,18.838,74.48,BHH,-1.53733,0.0495842,0.00628442,0.971156 WW_domain_S183Y,WW_domain_183,Yap65,WW_domain,P46937,0.971157,NO,183,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.95,-4.033,2.083,5.35576,,,,,,1.594,,83.93,PPP,-1.48733,0.153962,0.00445513,0.971157 beta-lactamase_39_S233Y,beta-lactamase_39_233,TEM-1,beta-lactamase_39,P62593,0.971158,NO,233,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.886,-4.293,2.407,,0.016,E,B,0.27,-1.01,5.361,,77.62,BPO,-1.17267,0.0495842,0.00311415,0.971158 beta-lactamase_0_K213V,beta-lactamase_0_213,TEM-1,beta-lactamase_0,P62593,0.971168,NO,213,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.81,-3.705,1.895,,0.67,,A,2.34,0.29,3.015,,67.83,ABH,-1.57767,0.0500837,0.00610411,0.971168 gb1_T277A,gb1_277,gb1,gb1,P06654,0.971177,NO,277,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.771,-2.096,0.325,,,,,,,0.824,,35.71,BPH,-1.54833,0.177985,0.00348258,0.971177 kka2_1:2_T146D,kka2_1:2_146,Kka2,kka2_1:2,P00552,0.971181,NO,146,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.978,-3.05,0.072,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.295029,0.00606474,0.971181 beta-lactamase_156_T107N,beta-lactamase_156_107,TEM-1,beta-lactamase_156,P62593,0.971183,NO,107,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.117,-3.473,2.356,,,G,A,0.22,-0.06,0.341,,67.83,HPA,-1.265,0.111618,0.00239347,0.971183 beta-lactamase_0_L219Q,beta-lactamase_0_219,TEM-1,beta-lactamase_0,P62593,0.971186,NO,219,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.313,-4.292,2.979,,,I,A,0.55,-0.51,6.513,6.513,74.48,HHB,-1.21533,0.0500837,0.00664345,0.971186 beta-lactamase_156_A34W,beta-lactamase_156_34,TEM-1,beta-lactamase_156,P62593,0.971192,NO,34,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.059,-2.89,0.831,,,H,A,0.46,-0.54,3.614,,73.78,AHA,-1.74967,0.111618,0.00407913,0.971192 beta-lactamase_0_P165G,beta-lactamase_0_165,TEM-1,beta-lactamase_0,P62593,0.971193,NO,165,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.373,-3.429,2.056,,0.203,T,A,0.52,-0.31,3.242,,73.78,AOA,-1.359,0.0500837,0.00549538,0.971193 beta-lactamase_39_S57E,beta-lactamase_39_57,TEM-1,beta-lactamase_39,P62593,0.971199,NO,57,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.918,-2.903,0.985,,0.352,E,B,0.27,-0.18,2.3,,72.73,APH,-2.29167,0.0495842,0.00492804,0.971199 beta-lactamase_2500_I54L,beta-lactamase_2500_54,TEM-1,beta-lactamase_2500,P62593,0.971205,NO,54,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-2.838,-2.471,-0.367,,0.669,E,B,0.48,-0.14,3.946,,73.78,BHH,-2.337,0.361275,0.00403589,0.971205 beta-lactamase_2500_S57V,beta-lactamase_2500_57,TEM-1,beta-lactamase_2500,P62593,0.971206,NO,57,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.918,-2.889,0.971,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.361275,0.00492804,0.971206 kka2_1:8_R66K,kka2_1:8_66,Kka2,kka2_1:8,P00552,0.971207,NO,66,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-0.922,-2.125,1.203,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.100394,0.00161025,0.971207 kka2_1:8_R66K,kka2_1:8_66,Kka2,kka2_1:8,P00552,0.971207,NO,66,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-0.922,-2.125,1.203,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.100394,0.00161025,0.971207 Pab1_E174S,Pab1_174,Pab1,Pab1,P04147,0.971214,NO,174,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.422,-3.143,1.721,,0.578,S,A,,0.38,,,,HAA,-1.65133,0.175299,0.00077863,0.971214 beta-lactamase_2500_D271P,beta-lactamase_2500_271,TEM-1,beta-lactamase_2500,P62593,0.971217,NO,271,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.361275,0.00752082,0.971217 beta-lactamase_625_T187M,beta-lactamase_625_187,TEM-1,beta-lactamase_625,P62593,0.971224,NO,187,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.401,-4.516,3.115,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.213352,0.00491782,0.971224 beta-lactamase_0_L188P,beta-lactamase_0_188,TEM-1,beta-lactamase_0,P62593,0.971246,NO,188,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.166,-4.109,2.943,,,H,A,0.55,-0.3,2.739,,60.14,PHB,-1.47033,0.0500837,0.00295687,0.971246 beta-lactamase_A16T,beta-lactamase_16,TEM-1,beta-lactamase,P62593,0.971251,NO,16,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,,-2.21,0.275,,,,,,,,,,HHH,,0.221079,0.00245392,0.971251 WW_domain_P172L,WW_domain_172,Yap65,WW_domain,P46937,0.971262,NO,172,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.035,-3.36,2.325,,,,,,,,,,HOH,-1.233,0.153962,0.000991485,0.971262 beta-lactamase_2500_R176Q,beta-lactamase_2500_176,TEM-1,beta-lactamase_2500,P62593,0.971271,NO,176,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-0.863,-3.449,2.586,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.361275,0.00105554,0.971271 beta-lactamase_39_Y103D,beta-lactamase_39_103,TEM-1,beta-lactamase_39,P62593,0.971275,NO,103,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-1.33,-3.794,2.464,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.0495842,0.00443048,0.971275 beta-lactamase_156_P143Y,beta-lactamase_156_143,TEM-1,beta-lactamase_156,P62593,0.971279,NO,143,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.967,-4.337,3.37,,0.075,H,A,0.52,-0.37,0.479,,66.78,OOB,-1.354,0.111618,0.00114551,0.971279 kka2_1:8_L67V,kka2_1:8_67,Kka2,kka2_1:8,P00552,0.971279,NO,67,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.741,-2.882,2.141,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.100394,0.00102787,0.971279 kka2_1:8_L67V,kka2_1:8_67,Kka2,kka2_1:8,P00552,0.971279,NO,67,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.741,-2.882,2.141,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.100394,0.00102787,0.971279 beta-lactamase_39_K144W,beta-lactamase_39_144,TEM-1,beta-lactamase_39,P62593,0.971283,NO,144,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-2.388,-5.522,3.134,,0.863,H,A,2.34,1.27,14.556,14.556,77.62,OBA,-1.904,0.0495842,0.00481141,0.971283 beta-lactamase_H156P,beta-lactamase_156,TEM-1,beta-lactamase,P62593,0.971291,NO,156,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-3.156,-2.552,-0.604,6.00284,0.753,S,A,0.72,-0.6,6.456,6.456,77.62,ABH,-1.932,0.221079,0.00468596,0.971291 beta-lactamase_625_T139I,beta-lactamase_625_139,TEM-1,beta-lactamase_625,P62593,0.971301,NO,139,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.901,-3.075,1.174,,0.216,H,A,0.22,0.39,2.256,,77.62,PPH,-2.04667,0.213352,0.00441837,0.971301 beta-lactamase_625_G194I,beta-lactamase_625_194,TEM-1,beta-lactamase_625,P62593,0.971305,NO,194,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.396,-4.133,2.737,,0.276,S,b,0.29,0.36,3.593,,67.83,POA,-1.832,0.213352,0.00392163,0.971305 beta-lactamase_39_W288Y,beta-lactamase_39_288,TEM-1,beta-lactamase_39,P62593,0.971311,NO,288,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,,,,,,,,,,,,,BHO,,0.0495842,,0.971311 kka2_1:2_K138H,kka2_1:2_138,Kka2,kka2_1:2,P00552,0.97132,NO,138,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-2.5,-3.509,1.009,,0.594,H,A,2.34,0.98,21.038,21.038,71.59,HBB,-2.48833,0.295029,0.00628542,0.97132 beta-lactamase_0_H24S,beta-lactamase_0_24,TEM-1,beta-lactamase_0,P62593,0.971323,NO,24,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-2.481,-1.903,-0.578,,,,,,,2.708,,93.01,OBO,-2.0035,0.0500837,0.00238894,0.971323 beta-lactamase_0_L223Y,beta-lactamase_0_223,TEM-1,beta-lactamase_0,P62593,0.971329,NO,223,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.055,-3.889,2.834,,0.27,,B,0.55,0.09,1.633,,74.48,HHO,-1.35033,0.0500837,0.00372793,0.971329 beta-lactamase_2500_F58A,beta-lactamase_2500_58,TEM-1,beta-lactamase_2500,P62593,0.971337,NO,58,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-2.914,-3.389,0.475,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.361275,0.00523369,0.971337 Pab1_E176A,Pab1_176,Pab1,Pab1,P04147,0.971343,NO,176,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.003,-1.933,-0.07,,,,,,,,,,AAO,-2.09933,0.175299,0.00264426,0.971343 gb1_T242I,gb1_242,gb1,gb1,P06654,0.971369,NO,242,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.245,-3.296,2.051,,,,,,,,,,APP,-1.444,0.177985,0.00243886,0.971369 beta-lactamase_39_D113P,beta-lactamase_39_113,TEM-1,beta-lactamase_39,P62593,0.971404,NO,113,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.829,-3.062,1.233,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.0495842,0.00474112,0.971404 beta-lactamase_V82V,beta-lactamase_82,TEM-1,beta-lactamase,P62593,0.971406,NO,82,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.325,-1.325,,5.27777,0.267,H,A,0.96,0.08,1.379,,93.01,BHA,-1.28567,0.221079,0.00397046,0.971406 beta-lactamase_625_K32D,beta-lactamase_625_32,TEM-1,beta-lactamase_625,P62593,0.971413,NO,32,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.984,-2.882,0.898,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.213352,0.00401283,0.971413 beta-lactamase_156_L137Q,beta-lactamase_156_137,TEM-1,beta-lactamase_156,P62593,0.971416,NO,137,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.03,-4.147,3.117,,,H,A,0.55,-0.38,0.674,,42.31,HHP,-1.58933,0.111618,0.00278599,0.971416 beta-lactamase_156_G141Q,beta-lactamase_156_141,TEM-1,beta-lactamase_156,P62593,0.971428,NO,141,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.828,-3.982,3.154,,0.575,T,l,0.29,-0.28,0.198,,64.69,HOO,-1.08933,0.111618,0.0012419,0.971428 beta-lactamase_39_A225Y,beta-lactamase_39_225,TEM-1,beta-lactamase_39,P62593,0.971436,NO,225,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.845,-4.327,2.482,,1,T,B,0.46,-0.38,9.874,9.874,74.48,OHO,-1.39967,0.0495842,0.00465057,0.971436 beta-lactamase_156_L218C,beta-lactamase_156_218,TEM-1,beta-lactamase_156,P62593,0.971451,NO,218,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.391,-4.928,3.537,,,I,b,0.55,-0.53,17.202,17.202,74.48,OHH,-1.58867,0.111618,0.00618274,0.971451 beta-lactamase_625_L111K,beta-lactamase_625_111,TEM-1,beta-lactamase_625,P62593,0.971451,NO,111,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.76,-3.773,2.013,,0.328,T,A,0.55,0.93,2.26,,64.34,BHP,-1.884,0.213352,0.00480671,0.971451 beta-lactamase_39_E35Y,beta-lactamase_39_35,TEM-1,beta-lactamase_39,P62593,0.971452,NO,35,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-0.869,-4.211,3.342,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.0495842,0.00174441,0.971452 beta-lactamase_156_S221H,beta-lactamase_156_221,TEM-1,beta-lactamase_156,P62593,0.971453,NO,221,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.754,-4.673,2.919,,0.624,H,A,0.27,-0.2,17.729,17.729,74.48,BPH,-1.59967,0.111618,0.0046094,0.971453 beta-lactamase_39_D33L,beta-lactamase_39_33,TEM-1,beta-lactamase_39,P62593,0.971455,NO,33,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.321,-2.326,0.005,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.0495842,0.00435556,0.971455 beta-lactamase_156_I45G,beta-lactamase_156_45,TEM-1,beta-lactamase_156,P62593,0.971456,NO,45,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-2.421,-3.565,1.144,,,E,B,0.48,-0.3,2.256,,77.62,HHA,-2.30267,0.111618,0.00452842,0.971456 beta-lactamase_625_K254Q,beta-lactamase_625_254,TEM-1,beta-lactamase_625,P62593,0.971461,NO,254,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.213352,0.00369,0.971461 beta-lactamase_39_A34W,beta-lactamase_39_34,TEM-1,beta-lactamase_39,P62593,0.971465,NO,34,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.059,-2.89,0.831,,,H,A,0.46,-0.54,13.292,13.292,73.78,AHA,-1.74967,0.0495842,0.00407913,0.971465 beta-lactamase_625_L199K,beta-lactamase_625_199,TEM-1,beta-lactamase_625,P62593,0.971467,NO,199,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-2.942,-2.994,0.052,,0.832,H,A,0.55,0.42,1.552,,77.62,PHH,-2.32933,0.213352,0.0048649,0.971467 kka2_1:8_I246E,kka2_1:8_246,Kka2,kka2_1:8,P00552,0.971471,NO,246,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-2.008,-3.889,1.881,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.100394,0.0139479,0.971471 kka2_1:8_I246E,kka2_1:8_246,Kka2,kka2_1:8,P00552,0.971471,NO,246,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-2.008,-3.889,1.881,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.100394,0.0139479,0.971471 beta-lactamase_39_R202K,beta-lactamase_39_202,TEM-1,beta-lactamase_39,P62593,0.971476,NO,202,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.292,-3.005,1.713,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.0495842,0.00321899,0.971476 beta-lactamase_156_S201W,beta-lactamase_156_201,TEM-1,beta-lactamase_156,P62593,0.971527,NO,201,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.183,-5.344,4.161,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.111618,0.00198815,0.971527 beta-lactamase_2500_Q97N,beta-lactamase_2500_97,TEM-1,beta-lactamase_2500,P62593,0.971545,NO,97,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.072,-3.773,1.701,,0.823,G,A,0.64,2.42,1.157,,77.62,PPP,-2.43833,0.361275,0.0045116,0.971545 beta-lactamase_39_C121A,beta-lactamase_39_121,TEM-1,beta-lactamase_39,P62593,0.97155,NO,121,C,A,CA,Special,Hydrophobic,5.07,6,0.93,195,121,89,-32,108.5,88.6,-19.9,-0.953,-2.902,1.949,,,H,A,0.46,-0.81,7.644,,63.29,HOP,-1.46767,0.0495842,0.000744322,0.97155 beta-lactamase_2500_I206R,beta-lactamase_2500_206,TEM-1,beta-lactamase_2500,P62593,0.971561,NO,206,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-2.429,-3.125,0.696,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.361275,0.00528934,0.971561 gb1_K230T,gb1_230,gb1,gb1,P06654,0.971561,NO,230,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.701,-3.339,1.638,,,,,,,0.166,,11.83,HBH,-1.52867,0.177985,0.00331703,0.971561 beta-lactamase_0_N50A,beta-lactamase_0_50,TEM-1,beta-lactamase_0,P62593,0.971568,NO,50,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-2.979,-1.868,-1.111,,0.912,T,A,0.61,1.24,9.874,9.874,77.62,HPP,-2.134,0.0500837,0.0047211,0.971568 beta-lactamase_V8D,beta-lactamase_8,TEM-1,beta-lactamase,P62593,0.971569,NO,8,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-2.358,-3.888,1.53,,,,,,,0.575,,77.62,BHH,-2.06267,0.221079,0.00226401,0.971569 beta-lactamase_156_L146W,beta-lactamase_156_146,TEM-1,beta-lactamase_156,P62593,0.971571,NO,146,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.462,-2.894,1.432,,0.007,H,A,0.55,-0.56,1.578,,64.69,AHP,-1.656,0.111618,0.00474542,0.971571 beta-lactamase_2500_D83E,beta-lactamase_2500_83,TEM-1,beta-lactamase_2500,P62593,0.971573,NO,83,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.066,-2.025,0.959,,0.354,H,A,0.75,0.22,0.239,,48.95,HAH,-1.34733,0.361275,0.00205968,0.971573 beta-lactamase_39_D48I,beta-lactamase_39_48,TEM-1,beta-lactamase_39,P62593,0.971574,NO,48,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.101,-4.047,2.946,,0.189,E,B,0.75,0.21,0.735,,50.35,HAH,-1.62467,0.0495842,0.0027273,0.971574 beta-lactamase_0_L137D,beta-lactamase_0_137,TEM-1,beta-lactamase_0,P62593,0.971585,NO,137,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.03,-4.128,3.098,,,H,A,0.55,-0.38,0.328,,42.31,HHP,-1.58933,0.0500837,0.00278599,0.971585 beta-lactamase_39_E169K,beta-lactamase_39_169,TEM-1,beta-lactamase_39,P62593,0.971585,NO,169,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.23,-3.226,1.996,,0.337,,A,1.04,1,15.633,15.633,73.08,PAH,-1.16533,0.0495842,0.00400994,0.971585 beta-lactamase_39_N134D,beta-lactamase_39_134,TEM-1,beta-lactamase_39,P62593,0.9716,NO,134,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-0.879,-3.087,2.208,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.0495842,0.000644786,0.9716 beta-lactamase_0_E46L,beta-lactamase_0_46,TEM-1,beta-lactamase_0,P62593,0.971602,NO,46,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.94,-2.216,0.276,,0.021,E,B,1.04,0.14,30.306,30.306,59.44,HAH,-2.079,0.0500837,0.00427568,0.971602 kka2_1:4_G95D,kka2_1:4_95,Kka2,kka2_1:4,P00552,0.971626,NO,95,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-2.403,-2.891,0.488,,0.126,E,B,0.29,-0.74,0.359,,71.59,HOA,-2.198,0.168804,0.00743616,0.971626 beta-lactamase_2500_T198C,beta-lactamase_2500_198,TEM-1,beta-lactamase_2500,P62593,0.97163,NO,198,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.168,-4.902,2.734,,0.489,,B,0.22,-0.13,0.37,,73.78,HPH,-1.98767,0.361275,0.004311,0.97163 beta-lactamase_156_D161F,beta-lactamase_156_161,TEM-1,beta-lactamase_156,P62593,0.971632,NO,161,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.891,-4.316,3.425,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.111618,0.000897697,0.971632 beta-lactamase_2500_I171D,beta-lactamase_2500_171,TEM-1,beta-lactamase_2500,P62593,0.971633,NO,171,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-2.431,-3.888,1.457,,0.361,,B,0.48,0.53,1.66,,77.62,HHO,-1.55533,0.361275,0.00623355,0.971633 beta-lactamase_0_R118I,beta-lactamase_0_118,TEM-1,beta-lactamase_0,P62593,0.971636,NO,118,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.413,-3.968,1.555,,0.457,H,A,1.2,1.39,3.961,,77.62,HBA,-1.785,0.0500837,0.00538794,0.971636 beta-lactamase_156_Q204T,beta-lactamase_156_204,TEM-1,beta-lactamase_156,P62593,0.971637,NO,204,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-1.382,-3.549,2.167,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.111618,0.00364106,0.971637 beta-lactamase_0_A185C,beta-lactamase_0_185,TEM-1,beta-lactamase_0,P62593,0.971639,NO,185,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.406,-4.699,3.293,,,H,A,0.46,-1.02,1.203,,65.03,HHP,-1.84033,0.0500837,0.00467449,0.971639 beta-lactamase_V257I,beta-lactamase_257,TEM-1,beta-lactamase,P62593,0.971651,NO,257,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.533,-1.95,0.417,5.31999,,E,B,0.96,-0.7,1.463,,58.74,HHH,-1.70967,0.221079,0.00756629,0.971651 beta-lactamase_2500_A170C,beta-lactamase_2500_170,TEM-1,beta-lactamase_2500,P62593,0.971655,NO,170,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.237,-4.736,3.499,,0.126,,L,0.46,-0.35,2.427,,64.69,AHH,-1.63267,0.361275,0.00431903,0.971655 Pab1_G163E,Pab1_163,Pab1,Pab1,P04147,0.971663,NO,163,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.809,-3.482,2.673,,0.356,B,g,,0.55,,,,POB,-1.80667,0.175299,0.00030953,0.971663 beta-lactamase_156_Y103R,beta-lactamase_156_103,TEM-1,beta-lactamase_156,P62593,0.971665,NO,103,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-1.33,-3.864,2.534,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.111618,0.00443048,0.971665 kka2_1:8_A87T,kka2_1:8_87,Kka2,kka2_1:8,P00552,0.971673,NO,87,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.917,-3.035,1.118,,1.039,S,L,0.46,1.57,16.115,16.115,65.53,AHO,-1.822,0.100394,0.00791281,0.971673 kka2_1:8_A87T,kka2_1:8_87,Kka2,kka2_1:8,P00552,0.971673,NO,87,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.917,-3.035,1.118,,1.039,S,L,0.46,1.57,16.115,16.115,65.53,AHO,-1.822,0.100394,0.00791281,0.971673 kka2_1:8_V214M,kka2_1:8_214,Kka2,kka2_1:8,P00552,0.971673,NO,214,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.261,-4.2,2.939,,0.117,E,B,1.48,-0.31,1.859,,64.39,OHH,-0.941667,0.100394,0.00692782,0.971673 kka2_1:8_V214M,kka2_1:8_214,Kka2,kka2_1:8,P00552,0.971673,NO,214,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.261,-4.2,2.939,,0.117,E,B,1.48,-0.31,1.859,,64.39,OHH,-0.941667,0.100394,0.00692782,0.971673 beta-lactamase_39_V101K,beta-lactamase_39_101,TEM-1,beta-lactamase_39,P62593,0.971675,NO,101,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.295,-3.742,2.447,,0.342,,B,0.44,0,2.96,,73.08,HHA,-1.54367,0.0495842,0.00374492,0.971675 beta-lactamase_P217T,beta-lactamase_217,TEM-1,beta-lactamase,P62593,0.97168,NO,217,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-2.062,-2.679,0.617,5.19872,0.496,I,A,0.99,-0.33,0.431,,74.48,OOH,-1.64333,0.221079,0.00463211,0.97168 beta-lactamase_625_R159K,beta-lactamase_625_159,TEM-1,beta-lactamase_625,P62593,0.971687,NO,159,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-0.94,-2.865,1.925,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.213352,0.00108472,0.971687 kka2_1:4_H106I,kka2_1:4_106,Kka2,kka2_1:4,P00552,0.97171,NO,106,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-3.13,-4.034,0.904,,1.065,.,a,0.17,-0.95,16.74,16.74,71.59,PBH,-2.10433,0.168804,0.00730778,0.97171 beta-lactamase_2500_I206A,beta-lactamase_2500_206,TEM-1,beta-lactamase_2500,P62593,0.971711,NO,206,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-2.429,-2.387,-0.042,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.361275,0.00528934,0.971711 beta-lactamase_39_E175G,beta-lactamase_39_175,TEM-1,beta-lactamase_39,P62593,0.971711,NO,175,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.336,-3.483,1.147,,0.551,,A,1.04,1.05,3.676,,77.62,AAB,-1.31233,0.0495842,0.00482205,0.971711 kka2_1:4_V80K,kka2_1:4_80,Kka2,kka2_1:4,P00552,0.971713,NO,80,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.144,-3.802,2.658,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.168804,0.00488211,0.971713 beta-lactamase_39_Q37K,beta-lactamase_39_37,TEM-1,beta-lactamase_39,P62593,0.971749,NO,37,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.134,-2.595,0.461,,0.613,H,A,0.64,1.98,22.282,22.282,73.08,APH,-2.06967,0.0495842,0.00425833,0.971749 gb1_K276I,gb1_276,gb1,gb1,P06654,0.971753,NO,276,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.456,-3.85,2.394,,,,,,,0.236,,12.72,PBP,-1.65133,0.177985,0.00620493,0.971753 beta-lactamase_39_T107N,beta-lactamase_39_107,TEM-1,beta-lactamase_39,P62593,0.971763,NO,107,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.117,-3.473,2.356,,,G,A,0.22,-0.06,2.686,,67.83,HPA,-1.265,0.0495842,0.00239347,0.971763 beta-lactamase_625_L192I,beta-lactamase_625_192,TEM-1,beta-lactamase_625,P62593,0.971763,NO,192,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.254,-2.519,1.265,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.213352,0.00558728,0.971763 beta-lactamase_0_P250W,beta-lactamase_0_250,TEM-1,beta-lactamase_0,P62593,0.971764,NO,250,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.0500837,0.00550899,0.971764 beta-lactamase_625_V82L,beta-lactamase_625_82,TEM-1,beta-lactamase_625,P62593,0.97177,NO,82,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.325,-2.426,1.101,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.213352,0.00397046,0.97177 beta-lactamase_2500_T139M,beta-lactamase_2500_139,TEM-1,beta-lactamase_2500,P62593,0.971771,NO,139,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.901,-4.659,2.758,,0.216,H,A,0.22,0.39,2.256,,77.62,PPH,-2.04667,0.361275,0.00441837,0.971771 beta-lactamase_2500_V31C,beta-lactamase_2500_31,TEM-1,beta-lactamase_2500,P62593,0.971777,NO,31,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.822,-3.252,1.43,,,H,A,0.44,-0.46,0.955,,73.78,BHB,-2.03767,0.361275,0.00478065,0.971777 beta-lactamase_39_R202C,beta-lactamase_39_202,TEM-1,beta-lactamase_39,P62593,0.971778,NO,202,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.292,-5.047,3.755,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.0495842,0.00321899,0.971778 beta-lactamase_2500_G154D,beta-lactamase_2500_154,TEM-1,beta-lactamase_2500,P62593,0.971788,NO,154,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.823,-2.317,1.494,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.361275,0.00180205,0.971788 beta-lactamase_156_L137H,beta-lactamase_156_137,TEM-1,beta-lactamase_156,P62593,0.971799,NO,137,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.03,-4.934,3.904,,,H,A,0.55,-0.38,0.674,,42.31,HHP,-1.58933,0.111618,0.00278599,0.971799 beta-lactamase_V29V,beta-lactamase_29,TEM-1,beta-lactamase,P62593,0.971802,NO,29,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-2.856,-2.856,,5.58481,0.733,H,A,0.23,-0.78,1.287,,93.01,HHB,-2.24733,0.221079,0.00318969,0.971802 beta-lactamase_0_L28H,beta-lactamase_0_28,TEM-1,beta-lactamase_0,P62593,0.971805,NO,28,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.579,-4.838,3.259,,0.277,H,A,0.55,-0.16,9.35,9.35,93.01,PHH,-2.11333,0.0500837,0.00359321,0.971805 beta-lactamase_W163K,beta-lactamase_163,TEM-1,beta-lactamase,P62593,0.971835,NO,163,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-1.843,-2.971,1.128,6.2765,0.467,,B,1.22,-0.5,3.642,,63.99,BHA,-1.269,0.221079,0.00418955,0.971835 beta-lactamase_39_T139P,beta-lactamase_39_139,TEM-1,beta-lactamase_39,P62593,0.971843,NO,139,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.901,-3.919,2.018,,0.216,H,A,0.22,0.39,0.421,,77.62,PPH,-2.04667,0.0495842,0.00441837,0.971843 Pab1_A178R,Pab1_178,Pab1,Pab1,P04147,0.97186,NO,178,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.579,-3.778,2.199,,0.019,H,A,0.64,0.64,2.7,,81.63,OHH,-1.61067,0.175299,0.00160192,0.97186 beta-lactamase_A200M,beta-lactamase_200,TEM-1,beta-lactamase,P62593,0.971868,NO,200,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.878,-4.732,2.854,5.19406,0.757,H,A,0.47,-0.19,0.436,,77.62,HHP,-2.001,0.221079,0.0060056,0.971868 beta-lactamase_G279A,beta-lactamase_279,TEM-1,beta-lactamase,P62593,0.971868,NO,279,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.038,-2.133,1.095,4.53882,,H,A,0.46,-0.97,3.066,,62.59,HOH,-1.36467,0.221079,0.0192826,0.971868 beta-lactamase_G85N,beta-lactamase_85,TEM-1,beta-lactamase,P62593,0.971868,NO,85,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.011,-3.501,2.49,5.58951,0.805,T,l,0.23,1.7,1.468,,63.64,HOP,-1.68733,0.221079,0.00252173,0.971868 beta-lactamase_P25S,beta-lactamase_25,TEM-1,beta-lactamase,P62593,0.971868,NO,25,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.526,-3.274,1.748,5.6134,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.221079,0.00347571,0.971868 beta-lactamase_2500_L167M,beta-lactamase_2500_167,TEM-1,beta-lactamase_2500,P62593,0.971875,NO,167,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.138,-2.673,1.535,,0.015,G,A,0.55,-0.63,7.813,,64.69,AHP,-1.30767,0.361275,0.00303566,0.971875 beta-lactamase_156_S266M,beta-lactamase_156_266,TEM-1,beta-lactamase_156,P62593,0.971876,NO,266,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.111618,0.0140785,0.971876 beta-lactamase_39_D83G,beta-lactamase_39_83,TEM-1,beta-lactamase_39,P62593,0.97188,NO,83,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.066,-2.429,1.363,,0.354,H,A,0.75,0.22,0.752,,48.95,HAH,-1.34733,0.0495842,0.00205968,0.97188 PSD95pdz3_Y392K,PSD95pdz3_392,PSD95pdz3,PSD95pdz3,P31016,0.971895,NO,392,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-1.437,-3.364,1.927,5.20337,,,,,11.725,,,,PHB,-1.51733,0.0758425,0.000935211,0.971895 beta-lactamase_625_T27M,beta-lactamase_625_27,TEM-1,beta-lactamase_625,P62593,0.9719,NO,27,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.905,-4.581,2.676,,0.007,H,A,0.22,-0.37,3.72,,93.01,APH,-1.97933,0.213352,0.00306559,0.9719 beta-lactamase_39_M184S,beta-lactamase_39_184,TEM-1,beta-lactamase_39,P62593,0.971903,NO,184,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.593,-3.463,1.87,,,H,A,0.55,-0.87,2.893,,62.94,HHH,-1.41,0.0495842,0.00356019,0.971903 beta-lactamase_2500_E175K,beta-lactamase_2500_175,TEM-1,beta-lactamase_2500,P62593,0.971938,NO,175,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.336,-2.673,0.337,,0.551,,A,1.04,1.05,5.316,,77.62,AAB,-1.31233,0.361275,0.00482205,0.971938 beta-lactamase_F14T,beta-lactamase_14,TEM-1,beta-lactamase,P62593,0.971938,NO,14,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-2.736,-2.584,-0.152,,,,,,,1.537,,93.01,HHH,-2.26133,0.221079,0.00277095,0.971938 gb1_T281S,gb1_281,gb1,gb1,P06654,0.971945,NO,281,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.828,-2.1,0.272,,,,,,,1.038,,35.71,HPA,-1.63667,0.177985,0.00284418,0.971945 beta-lactamase_2500_H287Y,beta-lactamase_2500_287,TEM-1,beta-lactamase_2500,P62593,0.971977,NO,287,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,,,,,,,,,,,,,BBH,-1.111,0.361275,,0.971977 beta-lactamase_0_S68G,beta-lactamase_0_68,TEM-1,beta-lactamase_0,P62593,0.971978,NO,68,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-0.913,-2.934,2.021,,0.064,G,A,0.27,-1.03,1.441,,64.69,HPP,-1.37233,0.0500837,0.000800065,0.971978 PSD95pdz3_N381M,PSD95pdz3_381,PSD95pdz3,PSD95pdz3,P31016,0.971987,NO,381,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-1.41,-4.387,2.977,5.66057,,,,,28.2162,,,,BPH,-1.37767,0.0758425,0.000265374,0.971987 kka2_1:8_S105K,kka2_1:8_105,Kka2,kka2_1:8,P00552,0.971995,NO,105,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.945,-3.628,1.683,,0.056,S,B,0.27,-1.04,2.115,,65.53,PPB,-2.17033,0.100394,0.00847233,0.971995 kka2_1:8_S105K,kka2_1:8_105,Kka2,kka2_1:8,P00552,0.971995,NO,105,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.945,-3.628,1.683,,0.056,S,B,0.27,-1.04,2.115,,65.53,PPB,-2.17033,0.100394,0.00847233,0.971995 beta-lactamase_39_E210W,beta-lactamase_39_210,TEM-1,beta-lactamase_39,P62593,0.972004,NO,210,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.319,-5.437,3.118,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.0495842,0.00663582,0.972004 beta-lactamase_39_E169T,beta-lactamase_39_169,TEM-1,beta-lactamase_39,P62593,0.972008,NO,169,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.23,-2.43,1.2,,0.337,,A,1.04,1,15.633,15.633,73.08,PAH,-1.16533,0.0495842,0.00400994,0.972008 beta-lactamase_156_V259M,beta-lactamase_156_259,TEM-1,beta-lactamase_156,P62593,0.972026,NO,259,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.111618,0.0070773,0.972026 Pab1_H134Q,Pab1_134,Pab1,Pab1,P04147,0.972043,NO,134,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-1.542,-3.606,2.064,,,,,,,,,,HBO,-1.346,0.175299,0.00116356,0.972043 beta-lactamase_625_D252W,beta-lactamase_625_252,TEM-1,beta-lactamase_625,P62593,0.972045,NO,252,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.213352,0.00575769,0.972045 beta-lactamase_39_T158M,beta-lactamase_39_158,TEM-1,beta-lactamase_39,P62593,0.972074,NO,158,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.116,-4.575,3.459,,0.036,,B,0.22,-0.85,2.755,,69.58,HPB,-1.269,0.0495842,0.00341825,0.972074 beta-lactamase_39_S266Y,beta-lactamase_39_266,TEM-1,beta-lactamase_39,P62593,0.972089,NO,266,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.0495842,0.0140785,0.972089 beta-lactamase_G39L,beta-lactamase_39,TEM-1,beta-lactamase,P62593,0.972089,NO,39,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.864,-3.751,1.887,5.35574,0.701,T,L,0.23,0.47,29.926,29.926,77.62,HOH,-1.53633,0.221079,0.00487611,0.972089 beta-lactamase_39_A77K,beta-lactamase_39_77,TEM-1,beta-lactamase_39,P62593,0.972097,NO,77,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.234,-3.628,2.394,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.0495842,0.00282362,0.972097 PSD95pdz3_L379F,PSD95pdz3_379,PSD95pdz3,PSD95pdz3,P31016,0.972103,NO,379,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.347,-3.299,1.952,5.37777,,,,,16.8762,,,,HHB,-1.35667,0.0758425,0.00029733,0.972103 beta-lactamase_39_E119T,beta-lactamase_39_119,TEM-1,beta-lactamase_39,P62593,0.972106,NO,119,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.412,-3.526,2.114,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.0495842,0.00386966,0.972106 beta-lactamase_625_G90W,beta-lactamase_625_90,TEM-1,beta-lactamase_625,P62593,0.972133,NO,90,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-2.091,-5.515,3.424,,0.598,T,A,0.29,0.32,0.319,,77.62,HOB,-1.52633,0.213352,0.00490273,0.972133 beta-lactamase_39_P105E,beta-lactamase_39_105,TEM-1,beta-lactamase_39,P62593,0.972134,NO,105,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.813,-3.437,2.624,,0.226,T,A,0.52,0.8,1.222,,63.29,POH,-1.01533,0.0495842,0.0011981,0.972134 beta-lactamase_2500_E175W,beta-lactamase_2500_175,TEM-1,beta-lactamase_2500,P62593,0.972145,NO,175,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.336,-5.537,3.201,,0.551,,A,1.04,1.05,5.316,,77.62,AAB,-1.31233,0.361275,0.00482205,0.972145 beta-lactamase_39_K254G,beta-lactamase_39_254,TEM-1,beta-lactamase_39,P62593,0.972146,NO,254,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.0495842,0.00369,0.972146 beta-lactamase_0_G142A,beta-lactamase_0_142,TEM-1,beta-lactamase_0,P62593,0.972153,NO,142,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.707,-2.85,2.143,,0.034,,p,0.29,-0.64,1.947,,64.69,OOO,-0.834,0.0500837,0.00060149,0.972153 beta-lactamase_156_V101F,beta-lactamase_156_101,TEM-1,beta-lactamase_156,P62593,0.972155,NO,101,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.295,-3.936,2.641,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.111618,0.00374492,0.972155 Pab1_K180D,Pab1_180,Pab1,Pab1,P04147,0.972156,NO,180,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.945,-2.546,0.601,,,,,,,,,,HBA,-1.575,0.175299,0.00295933,0.972156 beta-lactamase_0_L196E,beta-lactamase_0_196,TEM-1,beta-lactamase_0,P62593,0.972163,NO,196,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-2.478,-3.033,0.555,,0.518,S,A,0.55,1.35,6.513,6.513,77.62,AHH,-1.839,0.0500837,0.00512144,0.972163 Pab1_K180Y,Pab1_180,Pab1,Pab1,P04147,0.972168,NO,180,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.945,-4.199,2.254,,,,,,,,,,HBA,-1.575,0.175299,0.00295933,0.972168 WW_domain_S184D,WW_domain_184,Yap65,WW_domain,P46937,0.972168,NO,184,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.363,-3.143,1.78,5.06696,,,,,,,,,PPO,-1.39133,0.153962,0.00231095,0.972168 beta-lactamase_E166H,beta-lactamase_166,TEM-1,beta-lactamase,P62593,0.972171,NO,166,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.756,-4.668,2.912,5.60527,0.508,G,A,0.52,1.05,2.124,,73.08,OAH,-1.42233,0.221079,0.00512989,0.972171 beta-lactamase_Q37Q,beta-lactamase_37,TEM-1,beta-lactamase,P62593,0.972171,NO,37,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.134,-2.134,,5.69153,0.613,H,A,0.12,1.98,1.318,,73.08,APH,-2.06967,0.221079,0.00425833,0.972171 Pab1_E181Q,Pab1_181,Pab1,Pab1,P04147,0.972173,NO,181,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.767,-3.52,1.753,,,,,,,1.395,,73.83,BAH,-1.575,0.175299,0.00107557,0.972173 beta-lactamase_39_N152A,beta-lactamase_39_152,TEM-1,beta-lactamase_39,P62593,0.972197,NO,152,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-2.757,-2.374,-0.383,,0.863,H,A,0.61,0.92,4.038,,77.62,BPH,-2.97,0.0495842,0.00471429,0.972197 beta-lactamase_0_G226Q,beta-lactamase_0_226,TEM-1,beta-lactamase_0,P62593,0.972204,NO,226,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.461,-3.959,2.498,,0.701,T,l,0.29,-0.25,23.034,23.034,74.48,HOH,-1.42933,0.0500837,0.00665294,0.972204 beta-lactamase_2500_K53G,beta-lactamase_2500_53,TEM-1,beta-lactamase_2500,P62593,0.972209,NO,53,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-2.313,-2.824,0.511,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.361275,0.00383383,0.972209 beta-lactamase_2500_K30Q,beta-lactamase_2500_30,TEM-1,beta-lactamase_2500,P62593,0.972225,NO,30,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-2.307,-2.158,-0.149,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.361275,0.00448593,0.972225 beta-lactamase_625_T147H,beta-lactamase_625_147,TEM-1,beta-lactamase_625,P62593,0.972229,NO,147,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.149,-4.643,3.494,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.213352,0.00226017,0.972229 beta-lactamase_156_Y103I,beta-lactamase_156_103,TEM-1,beta-lactamase_156,P62593,0.972243,NO,103,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-1.33,-3.874,2.544,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.111618,0.00443048,0.972243 beta-lactamase_39_E102I,beta-lactamase_39_102,TEM-1,beta-lactamase_39,P62593,0.972255,NO,102,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.118,-4.045,1.927,,0.722,S,B,1.04,1.82,3.87,,73.08,HAH,-1.581,0.0495842,0.00486633,0.972255 beta-lactamase_156_D252P,beta-lactamase_156_252,TEM-1,beta-lactamase_156,P62593,0.972258,NO,252,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.111618,0.00575769,0.972258 beta-lactamase_625_I244Y,beta-lactamase_625_244,TEM-1,beta-lactamase_625,P62593,0.972262,NO,244,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.555,-4.031,2.476,,,E,B,0.48,-0.84,2.061,,77.62,OHH,-1.385,0.213352,0.00605379,0.972262 beta-lactamase_0_A246I,beta-lactamase_0_246,TEM-1,beta-lactamase_0,P62593,0.972269,NO,246,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.121,-2.179,0.058,,0.01,E,B,0.46,-1.01,1.201,,73.78,HHH,-1.55633,0.0500837,0.00569458,0.972269 Pab1_H134T,Pab1_134,Pab1,Pab1,P04147,0.972281,NO,134,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-1.542,-3.422,1.88,,,,,,,,,,HBO,-1.346,0.175299,0.00116356,0.972281 beta-lactamase_T147N,beta-lactamase_147,TEM-1,beta-lactamase,P62593,0.972288,NO,147,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.149,-2.415,1.266,5.37474,0.281,H,A,0.8,-0.68,2.838,,64.34,HPH,-1.456,0.221079,0.00226017,0.972288 beta-lactamase_39_L28M,beta-lactamase_39_28,TEM-1,beta-lactamase_39,P62593,0.972296,NO,28,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.579,-4.156,2.577,,0.277,H,A,0.55,-0.16,3.262,,93.01,PHH,-2.11333,0.0495842,0.00359321,0.972296 kka2_1:4_A41L,kka2_1:4_41,Kka2,kka2_1:4,P00552,0.972325,NO,41,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.879,-3.033,1.154,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.168804,0.00543332,0.972325 beta-lactamase_39_D271S,beta-lactamase_39_271,TEM-1,beta-lactamase_39,P62593,0.972341,NO,271,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.0495842,0.00752082,0.972341 beta-lactamase_2500_N98M,beta-lactamase_2500_98,TEM-1,beta-lactamase_2500,P62593,0.972347,NO,98,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-2.973,-4.74,1.767,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.361275,0.00505389,0.972347 beta-lactamase_K53G,beta-lactamase_53,TEM-1,beta-lactamase,P62593,0.972351,NO,53,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-2.313,-2.824,0.511,5.93654,0.589,,B,1.82,1.15,19.72,19.72,77.62,OBH,-2.1,0.221079,0.00383383,0.972351 beta-lactamase_156_G253E,beta-lactamase_156_253,TEM-1,beta-lactamase_156,P62593,0.972352,NO,253,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.111618,0.00786358,0.972352 beta-lactamase_625_L100Q,beta-lactamase_625_100,TEM-1,beta-lactamase_625,P62593,0.972356,NO,100,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.218,-4.259,3.041,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.213352,0.00413885,0.972356 Pab1_D151Y,Pab1_151,Pab1,Pab1,P04147,0.972371,NO,151,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.399,-4.205,1.806,,,,,,,,,,OAH,-1.51767,0.175299,0.00228155,0.972371 beta-lactamase_39_E272F,beta-lactamase_39_272,TEM-1,beta-lactamase_39,P62593,0.972376,NO,272,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.127,,,,0.081,H,A,0.43,-0.97,12.983,12.983,63.64,AAB,-1.56333,0.0495842,0.00545371,0.972376 beta-lactamase_156_P25C,beta-lactamase_156_25,TEM-1,beta-lactamase_156,P62593,0.972381,NO,25,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.526,-5.046,3.52,,0.624,H,A,0.52,0.14,1.079,,73.08,BOA,-2.15367,0.111618,0.00347571,0.972381 kka2_1:8_T28G,kka2_1:8_28,Kka2,kka2_1:8,P00552,0.972388,NO,28,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.883,-2.414,0.531,,0.353,S,B,0.22,2.02,18.114,18.114,63.64,PPH,-1.74467,0.100394,0.00743084,0.972388 kka2_1:8_T28G,kka2_1:8_28,Kka2,kka2_1:8,P00552,0.972388,NO,28,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.883,-2.414,0.531,,0.353,S,B,0.22,2.02,18.114,18.114,63.64,PPH,-1.74467,0.100394,0.00743084,0.972388 beta-lactamase_2500_Q203R,beta-lactamase_2500_203,TEM-1,beta-lactamase_2500,P62593,0.972417,NO,203,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.168,-2.451,0.283,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.361275,0.00631514,0.972417 beta-lactamase_156_V42L,beta-lactamase_156_42,TEM-1,beta-lactamase_156,P62593,0.972426,NO,42,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.564,-1.709,0.145,,0.017,E,B,0.44,-0.51,2.576,,63.99,BHO,-1.042,0.111618,0.00404515,0.972426 beta-lactamase_39_W163F,beta-lactamase_39_163,TEM-1,beta-lactamase_39,P62593,0.972437,NO,163,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-1.843,-3.138,1.295,,0.467,,B,0.47,-0.5,15.095,15.095,63.99,BHA,-1.269,0.0495842,0.00418955,0.972437 beta-lactamase_G226D,beta-lactamase_226,TEM-1,beta-lactamase,P62593,0.972449,NO,226,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.461,-1.914,0.453,5.70682,0.701,T,l,0.77,-0.25,3.199,,74.48,HOH,-1.42933,0.221079,0.00665294,0.972449 Pab1_E176G,Pab1_176,Pab1,Pab1,P04147,0.97245,NO,176,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.003,-2.306,0.303,,,,,,,,,,AAO,-2.09933,0.175299,0.00264426,0.97245 kka2_1:4_E142C,kka2_1:4_142,Kka2,kka2_1:4,P00552,0.972458,NO,142,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.221,-5.114,2.893,,0.471,H,A,1.52,0.85,3.693,,65.53,HAB,-2.08033,0.168804,0.00748883,0.972458 beta-lactamase_0_P65D,beta-lactamase_0_65,TEM-1,beta-lactamase_0,P62593,0.972471,NO,65,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.894,-3.578,2.684,,0.098,E,B,0.52,-0.62,0.663,,40.56,HOH,-1.03233,0.0500837,0.00152776,0.972471 beta-lactamase_156_K254C,beta-lactamase_156_254,TEM-1,beta-lactamase_156,P62593,0.972476,NO,254,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.111618,0.00369,0.972476 beta-lactamase_39_R162D,beta-lactamase_39_162,TEM-1,beta-lactamase_39,P62593,0.97249,NO,162,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.016,-3.754,2.738,,0.124,S,B,1.2,-0.37,31.656,31.656,64.69,ABH,-1.25,0.0495842,0.000561334,0.97249 kka2_1:8_Q26C,kka2_1:8_26,Kka2,kka2_1:8,P00552,0.972496,NO,26,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.18,-5.205,3.025,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.100394,0.00708962,0.972496 kka2_1:8_Q26C,kka2_1:8_26,Kka2,kka2_1:8,P00552,0.972496,NO,26,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.18,-5.205,3.025,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.100394,0.00708962,0.972496 beta-lactamase_39_A148F,beta-lactamase_39_148,TEM-1,beta-lactamase_39,P62593,0.972514,NO,148,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.757,-4.389,2.632,,0.379,H,A,0.46,-0.55,3.551,,72.73,PHH,-1.40167,0.0495842,0.00547053,0.972514 beta-lactamase_S221I,beta-lactamase_221,TEM-1,beta-lactamase,P62593,0.972514,NO,221,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.754,-3.812,2.058,5.77407,0.624,H,A,0.74,-0.2,0.383,,74.48,BPH,-1.59967,0.221079,0.0046094,0.972514 beta-lactamase_2500_Q37C,beta-lactamase_2500_37,TEM-1,beta-lactamase_2500,P62593,0.972515,NO,37,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.134,-5.133,2.999,,0.613,H,A,0.64,1.98,1.318,,73.08,APH,-2.06967,0.361275,0.00425833,0.972515 kka2_1:2_L103R,kka2_1:2_103,Kka2,kka2_1:2,P00552,0.972522,NO,103,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-2.362,-3.979,1.617,,0.394,T,A,0.55,-0.99,3.499,,63.64,HHP,-1.534,0.295029,0.00574792,0.972522 beta-lactamase_0_Q37N,beta-lactamase_0_37,TEM-1,beta-lactamase_0,P62593,0.972532,NO,37,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.134,-3.706,1.572,,0.613,H,A,0.64,1.98,4.001,,73.08,APH,-2.06967,0.0500837,0.00425833,0.972532 beta-lactamase_0_E164D,beta-lactamase_0_164,TEM-1,beta-lactamase_0,P62593,0.972541,NO,164,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-0.948,-2.949,2.001,,0.011,T,B,1.04,-0.4,1.011,,64.69,HAO,-1.388,0.0500837,0.00137286,0.972541 beta-lactamase_2500_L150V,beta-lactamase_2500_150,TEM-1,beta-lactamase_2500,P62593,0.972551,NO,150,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.326,-2.348,1.022,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.361275,0.00463171,0.972551 beta-lactamase_0_A200G,beta-lactamase_0_200,TEM-1,beta-lactamase_0,P62593,0.972553,NO,200,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.878,-2.76,0.882,,0.757,H,A,0.46,-0.19,16.368,16.368,77.62,HHP,-2.001,0.0500837,0.0060056,0.972553 beta-lactamase_G85E,beta-lactamase_85,TEM-1,beta-lactamase,P62593,0.972554,NO,85,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.011,-3.408,2.397,5.58951,0.805,T,l,0.23,1.7,1.468,,63.64,HOP,-1.68733,0.221079,0.00252173,0.972554 beta-lactamase_156_M127Y,beta-lactamase_156_127,TEM-1,beta-lactamase_156,P62593,0.972561,NO,127,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-2.251,-2.954,0.703,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.111618,0.00437927,0.972561 beta-lactamase_39_Q97W,beta-lactamase_39_97,TEM-1,beta-lactamase_39,P62593,0.972562,NO,97,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.072,-5.457,3.385,,0.823,G,A,0.64,2.42,4.457,,77.62,PPP,-2.43833,0.0495842,0.0045116,0.972562 beta-lactamase_39_L137I,beta-lactamase_39_137,TEM-1,beta-lactamase_39,P62593,0.972569,NO,137,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.03,-2.064,1.034,,,H,A,0.55,-0.38,0.674,,42.31,HHP,-1.58933,0.0495842,0.00278599,0.972569 beta-lactamase_S221C,beta-lactamase_221,TEM-1,beta-lactamase,P62593,0.972572,NO,221,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.754,-3.097,1.343,5.77407,0.624,H,A,0.74,-0.2,0.383,,74.48,BPH,-1.59967,0.221079,0.0046094,0.972572 beta-lactamase_0_K53D,beta-lactamase_0_53,TEM-1,beta-lactamase_0,P62593,0.972584,NO,53,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-2.313,-3.725,1.412,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.0500837,0.00383383,0.972584 beta-lactamase_625_R159I,beta-lactamase_625_159,TEM-1,beta-lactamase_625,P62593,0.972591,NO,159,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-0.94,-4.036,3.096,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.213352,0.00108472,0.972591 E1_Ubiquitin_T68Q,E1_Ubiquitin_68,Uba1,E1_Ubiquitin,P0CG63,0.972591,NO,68,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,,,,,,,,,,,,,OPH,-1.039,0.18783,0.00314321,0.972591 beta-lactamase_39_L135C,beta-lactamase_39_135,TEM-1,beta-lactamase_39,P62593,0.972596,NO,135,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.002,-4.691,3.689,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.0495842,0.00244423,0.972596 beta-lactamase_156_L49Q,beta-lactamase_156_49,TEM-1,beta-lactamase_156,P62593,0.972598,NO,49,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.897,-2.823,0.926,,0.131,T,A,0.55,0.04,3.112,,64.69,AHP,-1.99233,0.111618,0.00401477,0.972598 beta-lactamase_156_A225F,beta-lactamase_156_225,TEM-1,beta-lactamase_156,P62593,0.972604,NO,225,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.845,-4.402,2.557,,1,T,B,0.46,-0.38,11.722,11.722,74.48,OHO,-1.39967,0.111618,0.00465057,0.972604 beta-lactamase_2500_E56S,beta-lactamase_2500_56,TEM-1,beta-lactamase_2500,P62593,0.972607,NO,56,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.043,-2.169,0.126,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.361275,0.00238534,0.972607 beta-lactamase_0_I245P,beta-lactamase_0_245,TEM-1,beta-lactamase_0,P62593,0.972616,NO,245,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.0500837,0.00391032,0.972616 beta-lactamase_0_L28P,beta-lactamase_0_28,TEM-1,beta-lactamase_0,P62593,0.97262,NO,28,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.579,-4.027,2.448,,0.277,H,A,0.55,-0.16,9.35,9.35,93.01,PHH,-2.11333,0.0500837,0.00359321,0.97262 beta-lactamase_E56S,beta-lactamase_56,TEM-1,beta-lactamase,P62593,0.972621,NO,56,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.043,-2.169,0.126,5.65281,0.198,E,B,0.52,0.31,2.022,,72.73,HAP,-1.94033,0.221079,0.00238534,0.972621 beta-lactamase_2500_Q276Y,beta-lactamase_2500_276,TEM-1,beta-lactamase_2500,P62593,0.972622,NO,276,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.361275,0.0191712,0.972622 beta-lactamase_39_A211N,beta-lactamase_39_211,TEM-1,beta-lactamase_39,P62593,0.972629,NO,211,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.896,-2.729,0.833,,0.369,T,A,0.46,-0.69,1.419,,77.62,AHA,-1.94633,0.0495842,0.00648183,0.972629 beta-lactamase_0_T138V,beta-lactamase_0_138,TEM-1,beta-lactamase_0,P62593,0.972634,NO,138,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.506,-3.689,1.183,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.0500837,0.00487868,0.972634 beta-lactamase_39_H94M,beta-lactamase_39_94,TEM-1,beta-lactamase_39,P62593,0.972635,NO,94,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-2.5,-3.474,0.974,,0.776,,B,0.17,1.24,11.583,11.583,77.62,HBH,-1.872,0.0495842,0.00389226,0.972635 beta-lactamase_2500_K286G,beta-lactamase_2500_286,TEM-1,beta-lactamase_2500,P62593,0.972636,NO,286,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.361275,,0.972636 kka2_1:4_A144C,kka2_1:4_144,Kka2,kka2_1:4,P00552,0.972654,NO,144,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.859,-4.523,3.664,,,H,A,0.46,0.21,6.844,,52.65,BHB,-1.72933,0.168804,0.00231095,0.972654 beta-lactamase_156_A34K,beta-lactamase_156_34,TEM-1,beta-lactamase_156,P62593,0.972667,NO,34,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.059,-3.736,1.677,,,H,A,0.46,-0.54,3.614,,73.78,AHA,-1.74967,0.111618,0.00407913,0.972667 beta-lactamase_K30V,beta-lactamase_30,TEM-1,beta-lactamase,P62593,0.972667,NO,30,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-2.307,-2.807,0.5,5.30605,0.142,H,A,1.82,-0.65,2.434,,93.01,HBH,-2.32833,0.221079,0.00448593,0.972667 kka2_1:4_G181L,kka2_1:4_181,Kka2,kka2_1:4,P00552,0.972679,NO,181,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-2.698,-3.595,0.897,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.168804,0.00728319,0.972679 beta-lactamase_625_V214Q,beta-lactamase_625_214,TEM-1,beta-lactamase_625,P62593,0.972711,NO,214,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.299,-4.141,2.842,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.213352,0.00628442,0.972711 beta-lactamase_156_D33N,beta-lactamase_156_33,TEM-1,beta-lactamase_156,P62593,0.972712,NO,33,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.321,-2.983,0.662,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.111618,0.00435556,0.972712 beta-lactamase_0_V157F,beta-lactamase_0_157,TEM-1,beta-lactamase_0,P62593,0.972722,NO,157,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.751,-3.968,2.217,,0.308,S,a,0.44,-0.75,3.106,,69.58,BHP,-2.00767,0.0500837,0.00506849,0.972722 beta-lactamase_2500_I206T,beta-lactamase_2500_206,TEM-1,beta-lactamase_2500,P62593,0.972722,NO,206,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-2.429,-2.077,-0.352,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.361275,0.00528934,0.972722 beta-lactamase_I11Y,beta-lactamase_11,TEM-1,beta-lactamase,P62593,0.972726,NO,11,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.745,-3.74,1.995,,,,,,,3.135,,66.08,HHO,-1.79467,0.221079,0.00261325,0.972726 kka2_1:1_W15G,kka2_1:1_15,Kka2,kka2_1:1,P00552,0.972733,NO,15,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-1.392,-3.656,2.264,,0.01,G,A,0.47,0.15,20.149,20.149,52.27,HHH,-2.10533,0.520039,0.00585505,0.972733 beta-lactamase_39_A225R,beta-lactamase_39_225,TEM-1,beta-lactamase_39,P62593,0.972755,NO,225,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.845,-2.864,1.019,,1,T,B,0.46,-0.38,9.874,9.874,74.48,OHO,-1.39967,0.0495842,0.00465057,0.972755 beta-lactamase_39_E175Q,beta-lactamase_39_175,TEM-1,beta-lactamase_39,P62593,0.972759,NO,175,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.336,-3.092,0.756,,0.551,,A,1.04,1.05,3.676,,77.62,AAB,-1.31233,0.0495842,0.00482205,0.972759 beta-lactamase_2500_L160C,beta-lactamase_2500_160,TEM-1,beta-lactamase_2500,P62593,0.972774,NO,160,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.977,-4.68,3.703,,0.022,,B,0.55,-0.6,0.895,,44.41,BHA,-0.936,0.361275,0.00193775,0.972774 beta-lactamase_0_A133C,beta-lactamase_0_133,TEM-1,beta-lactamase_0,P62593,0.972776,NO,133,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.186,-4.706,3.52,,,H,A,0.46,-0.86,2.148,,67.83,HHP,-0.988333,0.0500837,0.00468022,0.972776 beta-lactamase_39_Q97P,beta-lactamase_39_97,TEM-1,beta-lactamase_39,P62593,0.972783,NO,97,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.072,-2.583,0.511,,0.823,G,A,0.64,2.42,4.457,,77.62,PPP,-2.43833,0.0495842,0.0045116,0.972783 beta-lactamase_L89M,beta-lactamase_89,TEM-1,beta-lactamase,P62593,0.972787,NO,89,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.096,-2.928,1.832,5.41092,0.168,T,A,1.75,0.63,1.599,,64.34,PHO,-1.75767,0.221079,0.00207068,0.972787 beta-lactamase_2500_Q97H,beta-lactamase_2500_97,TEM-1,beta-lactamase_2500,P62593,0.972791,NO,97,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.072,-4.636,2.564,,0.823,G,A,0.64,2.42,1.157,,77.62,PPP,-2.43833,0.361275,0.0045116,0.972791 kka2_1:8_D101C,kka2_1:8_101,Kka2,kka2_1:8,P00552,0.972795,NO,101,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.028,-5.093,4.065,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.100394,0.00423361,0.972795 kka2_1:8_D101C,kka2_1:8_101,Kka2,kka2_1:8,P00552,0.972795,NO,101,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.028,-5.093,4.065,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.100394,0.00423361,0.972795 beta-lactamase_0_A215T,beta-lactamase_0_215,TEM-1,beta-lactamase_0,P62593,0.972808,NO,215,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.503,-2.291,0.788,,,,a,0.46,-0.93,0.494,,74.48,HHO,-1.42633,0.0500837,0.00544007,0.972808 kka2_1:2_R202M,kka2_1:2_202,Kka2,kka2_1:2,P00552,0.972829,NO,202,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.761,-4.784,3.023,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.295029,0.00696498,0.972829 kka2_1:2_A176E,kka2_1:2_176,Kka2,kka2_1:2,P00552,0.972832,NO,176,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.621,-2.534,0.913,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.295029,0.0083587,0.972832 kka2_1:8_L126M,kka2_1:8_126,Kka2,kka2_1:8,P00552,0.972835,NO,126,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.246,-4.129,2.883,,0.285,S,B,1.59,0.12,4.443,,51.89,PHA,-1.744,0.100394,0.0066485,0.972835 kka2_1:8_L126M,kka2_1:8_126,Kka2,kka2_1:8,P00552,0.972835,NO,126,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.246,-4.129,2.883,,0.285,S,B,1.59,0.12,4.443,,51.89,PHA,-1.744,0.100394,0.0066485,0.972835 beta-lactamase_156_E56M,beta-lactamase_156_56,TEM-1,beta-lactamase_156,P62593,0.972843,NO,56,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.043,-4.624,2.581,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.111618,0.00238534,0.972843 beta-lactamase_625_R176F,beta-lactamase_625_176,TEM-1,beta-lactamase_625,P62593,0.972843,NO,176,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-0.863,-4.292,3.429,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.213352,0.00105554,0.972843 kka2_1:8_G245Q,kka2_1:8_245,Kka2,kka2_1:8,P00552,0.972844,NO,245,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.812,-4.042,3.23,,0.655,T,g,0.75,0.03,1.148,,65.53,HOH,-1.19833,0.100394,0.00683899,0.972844 kka2_1:8_G245Q,kka2_1:8_245,Kka2,kka2_1:8,P00552,0.972844,NO,245,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.812,-4.042,3.23,,0.655,T,g,0.75,0.03,1.148,,65.53,HOH,-1.19833,0.100394,0.00683899,0.972844 beta-lactamase_625_Q203C,beta-lactamase_625_203,TEM-1,beta-lactamase_625,P62593,0.972852,NO,203,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.168,-5.086,2.918,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.213352,0.00631514,0.972852 beta-lactamase_156_T131P,beta-lactamase_156_131,TEM-1,beta-lactamase_156,P62593,0.972855,NO,131,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.328,-3.82,2.492,,,H,A,0.22,-0.69,2.031,,67.48,PPH,-1.00867,0.111618,0.00345886,0.972855 beta-lactamase_39_L160C,beta-lactamase_39_160,TEM-1,beta-lactamase_39,P62593,0.972884,NO,160,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.977,-4.68,3.703,,0.022,,B,0.55,-0.6,0.895,,44.41,BHA,-0.936,0.0495842,0.00193775,0.972884 beta-lactamase_0_M209T,beta-lactamase_0_209,TEM-1,beta-lactamase_0,P62593,0.972886,NO,209,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.442,-3.52,2.078,,,H,A,0.55,-0.97,3.876,,64.69,HHA,-1.52633,0.0500837,0.00625021,0.972886 PSD95pdz3_A370M,PSD95pdz3_370,PSD95pdz3,PSD95pdz3,P31016,0.97289,NO,370,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.307,-4.162,2.855,5.22304,,,,,17.284,,,,PHP,-1.57967,0.0758425,0.000429106,0.97289 beta-lactamase_39_I258Y,beta-lactamase_39_258,TEM-1,beta-lactamase_39,P62593,0.972894,NO,258,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.0495842,0.007931,0.972894 gb1_T243L,gb1_243,gb1,gb1,P06654,0.9729,NO,243,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.415,-2.944,1.529,,,,,,,1.083,,37.28,PPP,-1.43233,0.177985,0.00308687,0.9729 beta-lactamase_625_L111F,beta-lactamase_625_111,TEM-1,beta-lactamase_625,P62593,0.972907,NO,111,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.76,-2.976,1.216,,0.328,T,A,0.55,0.93,2.26,,64.34,BHP,-1.884,0.213352,0.00480671,0.972907 kka2_1:1_A137L,kka2_1:1_137,Kka2,kka2_1:1,P00552,0.972911,NO,137,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.156,-1.375,-0.781,,0.029,H,A,0.46,0.34,1.323,,63.26,PHB,-2.559,0.520039,0.00515054,0.972911 beta-lactamase_V82I,beta-lactamase_82,TEM-1,beta-lactamase,P62593,0.972931,NO,82,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.325,-2.197,0.872,5.27777,0.267,H,A,0.96,0.08,1.379,,93.01,BHA,-1.28567,0.221079,0.00397046,0.972931 beta-lactamase_625_G142T,beta-lactamase_625_142,TEM-1,beta-lactamase_625,P62593,0.972934,NO,142,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.707,-3.568,2.861,,0.034,,p,0.29,-0.64,1.35,,64.69,OOO,-0.834,0.213352,0.00060149,0.972934 beta-lactamase_39_S122W,beta-lactamase_39_122,TEM-1,beta-lactamase_39,P62593,0.972935,NO,122,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.406,-5.469,3.063,,0.352,H,A,0.27,-0.54,2.004,,77.62,OPH,-1.39767,0.0495842,0.00497825,0.972935 kka2_1:4_A71E,kka2_1:4_71,Kka2,kka2_1:4,P00552,0.972942,NO,71,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.824,-2.798,0.974,,0.553,H,A,0.46,0.08,5.76,,64.39,HHP,-1.74033,0.168804,0.00727707,0.972942 beta-lactamase_39_E61G,beta-lactamase_39_61,TEM-1,beta-lactamase_39,P62593,0.972971,NO,61,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.115,-2.393,0.278,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.0495842,0.00440955,0.972971 beta-lactamase_S96Y,beta-lactamase_96,TEM-1,beta-lactamase,P62593,0.972971,NO,96,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.27,-4.345,2.075,5.29889,0.368,,b,0.25,0.39,32.348,32.348,73.78,HPP,-2.019,0.221079,0.00551835,0.972971 beta-lactamase_39_M153A,beta-lactamase_39_153,TEM-1,beta-lactamase_39,P62593,0.972979,NO,153,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-3.193,-2.415,-0.778,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.0495842,0.00509109,0.972979 beta-lactamase_G194A,beta-lactamase_194,TEM-1,beta-lactamase,P62593,0.972984,NO,194,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.396,-2.558,1.162,5.46622,0.276,S,b,0.77,0.36,3.593,,67.83,POA,-1.832,0.221079,0.00392163,0.972984 beta-lactamase_625_R63F,beta-lactamase_625_63,TEM-1,beta-lactamase_625,P62593,0.973002,NO,63,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-0.943,-4.214,3.271,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.213352,0.00126938,0.973002 beta-lactamase_2500_P25T,beta-lactamase_2500_25,TEM-1,beta-lactamase_2500,P62593,0.973009,NO,25,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.526,-3.483,1.957,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.361275,0.00347571,0.973009 beta-lactamase_625_L146Y,beta-lactamase_625_146,TEM-1,beta-lactamase_625,P62593,0.973019,NO,146,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.462,-3.821,2.359,,0.007,H,A,0.55,-0.56,2.16,,64.69,AHP,-1.656,0.213352,0.00474542,0.973019 kka2_1:4_G201A,kka2_1:4_201,Kka2,kka2_1:4,P00552,0.973023,NO,201,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.56,-3.247,1.687,,0.149,T,l,0.29,-0.57,0.284,,52.65,POB,-1.92233,0.168804,0.00820117,0.973023 beta-lactamase_0_M184A,beta-lactamase_0_184,TEM-1,beta-lactamase_0,P62593,0.973024,NO,184,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.593,-2.223,0.63,,,H,A,0.55,-0.87,13.292,13.292,62.94,HHH,-1.41,0.0500837,0.00356019,0.973024 beta-lactamase_0_L49R,beta-lactamase_0_49,TEM-1,beta-lactamase_0,P62593,0.973029,NO,49,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.897,-3.032,1.135,,0.131,T,A,0.55,0.04,13.838,13.838,64.69,AHP,-1.99233,0.0500837,0.00401477,0.973029 beta-lactamase_2500_N98E,beta-lactamase_2500_98,TEM-1,beta-lactamase_2500,P62593,0.973031,NO,98,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-2.973,-2.445,-0.528,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.361275,0.00505389,0.973031 kka2_1:8_G88R,kka2_1:8_88,Kka2,kka2_1:8,P00552,0.973031,NO,88,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.689,-3.209,1.52,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.100394,0.00685559,0.973031 kka2_1:8_G88R,kka2_1:8_88,Kka2,kka2_1:8,P00552,0.973031,NO,88,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.689,-3.209,1.52,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.100394,0.00685559,0.973031 beta-lactamase_2500_P172T,beta-lactamase_2500_172,TEM-1,beta-lactamase_2500,P62593,0.973035,NO,172,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.998,-3.409,2.411,,0.639,T,b,0.52,0.24,4.99,,74.48,HOP,-2.03067,0.361275,0.00312594,0.973035 beta-lactamase_625_R81K,beta-lactamase_625_81,TEM-1,beta-lactamase_625,P62593,0.973044,NO,81,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.466,-2.393,0.927,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.213352,0.00499763,0.973044 PSD95pdz3_K393M,PSD95pdz3_393,PSD95pdz3,PSD95pdz3,P31016,0.973047,NO,393,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.416,-4.162,2.746,5.42682,,,,,22.0122,,,,HBO,-1.4265,0.0758425,0.000879298,0.973047 kka2_1:1_P249R,kka2_1:1_249,Kka2,kka2_1:1,P00552,0.97305,NO,249,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.867,-3.291,1.424,,0.406,.,B,0.52,-0.01,8.037,8.037,92.05,HOA,-1.66867,0.520039,0.011045,0.97305 beta-lactamase_E169C,beta-lactamase_169,TEM-1,beta-lactamase,P62593,0.973055,NO,169,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.23,-5.088,3.858,5.78896,0.337,,A,0.52,1,1.806,,73.08,PAH,-1.16533,0.221079,0.00400994,0.973055 beta-lactamase_G251Q,beta-lactamase_251,TEM-1,beta-lactamase,P62593,0.973055,NO,251,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.907,-2.718,0.811,5.33865,0.506,T,l,0.73,0.17,10.663,,65.38,AOB,-2.06067,0.221079,0.00733416,0.973055 beta-lactamase_156_A40S,beta-lactamase_156_40,TEM-1,beta-lactamase_156,P62593,0.97306,NO,40,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.402,-3.164,1.762,,0.155,S,B,0.46,0.21,1.357,,73.78,OHB,-1.40267,0.111618,0.00490026,0.97306 beta-lactamase_39_S283C,beta-lactamase_39_283,TEM-1,beta-lactamase_39,P62593,0.973069,NO,283,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.0495842,0.0429138,0.973069 beta-lactamase_39_L79H,beta-lactamase_39_79,TEM-1,beta-lactamase_39,P62593,0.973076,NO,79,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.842,-4.903,4.061,,0.007,H,A,0.55,-0.16,0.823,,50.35,HHP,-1.44333,0.0495842,0.000947397,0.973076 beta-lactamase_39_E272V,beta-lactamase_39_272,TEM-1,beta-lactamase_39,P62593,0.973077,NO,272,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.127,,,,0.081,H,A,0.43,-0.97,12.983,12.983,63.64,AAB,-1.56333,0.0495842,0.00545371,0.973077 beta-lactamase_156_A40F,beta-lactamase_156_40,TEM-1,beta-lactamase_156,P62593,0.973087,NO,40,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.402,-4.227,2.825,,0.155,S,B,0.46,0.21,1.357,,73.78,OHB,-1.40267,0.111618,0.00490026,0.973087 beta-lactamase_39_Q97M,beta-lactamase_39_97,TEM-1,beta-lactamase_39,P62593,0.973094,NO,97,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.072,-3.413,1.341,,0.823,G,A,0.64,2.42,4.457,,77.62,PPP,-2.43833,0.0495842,0.0045116,0.973094 PSD95pdz3_K380W,PSD95pdz3_380,PSD95pdz3,PSD95pdz3,P31016,0.973101,NO,380,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.416,-5.004,3.588,5.87979,,,,,19.6722,,,,HBP,-1.391,0.0758425,0.000281399,0.973101 beta-lactamase_2500_A246S,beta-lactamase_2500_246,TEM-1,beta-lactamase_2500,P62593,0.973104,NO,246,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.121,-3.607,1.486,,0.01,E,B,0.46,-1.01,0.753,,73.78,HHH,-1.55633,0.361275,0.00569458,0.973104 beta-lactamase_39_R189W,beta-lactamase_39_189,TEM-1,beta-lactamase_39,P62593,0.973109,NO,189,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.844,-5.37,3.526,,0.278,H,A,1.2,1.01,12.11,12.11,72.73,HBB,-1.668,0.0495842,0.0050699,0.973109 beta-lactamase_156_R189Y,beta-lactamase_156_189,TEM-1,beta-lactamase_156,P62593,0.973121,NO,189,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.844,-3.134,1.29,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.111618,0.0050699,0.973121 beta-lactamase_39_E26D,beta-lactamase_39_26,TEM-1,beta-lactamase_39,P62593,0.973124,NO,26,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.454,-2.507,0.053,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.0495842,0.00297948,0.973124 beta-lactamase_F6V,beta-lactamase_6,TEM-1,beta-lactamase,P62593,0.973129,NO,6,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.847,-1.994,0.147,,,,,,,1.276,,67.83,BHB,-2.076,0.221079,0.00261627,0.973129 beta-lactamase_G194C,beta-lactamase_194,TEM-1,beta-lactamase,P62593,0.973129,NO,194,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.396,-5.097,3.701,5.46622,0.276,S,b,0.77,0.36,3.593,,67.83,POA,-1.832,0.221079,0.00392163,0.973129 beta-lactamase_39_E35Q,beta-lactamase_39_35,TEM-1,beta-lactamase_39,P62593,0.97313,NO,35,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-0.869,-3.292,2.423,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.0495842,0.00174441,0.97313 PSD95pdz3_Q374T,PSD95pdz3_374,PSD95pdz3,PSD95pdz3,P31016,0.973145,NO,374,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-1.699,-3.103,1.404,5.38825,,,,,17.3289,,,,APH,-1.47,0.0758425,0.000372298,0.973145 beta-lactamase_39_K254A,beta-lactamase_39_254,TEM-1,beta-lactamase_39,P62593,0.97315,NO,254,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.0495842,0.00369,0.97315 beta-lactamase_G142G,beta-lactamase_142,TEM-1,beta-lactamase,P62593,0.973167,NO,142,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.707,-0.707,,4.55474,0.034,,p,0.77,-0.64,1.947,,64.69,OOO,-0.834,0.221079,0.00060149,0.973167 PSD95pdz3_P346H,PSD95pdz3_346,PSD95pdz3,PSD95pdz3,P31016,0.973168,NO,346,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.236,-4.362,3.126,5.02406,,,,,14.6629,,,,OOH,-1.18367,0.0758425,0.000758563,0.973168 beta-lactamase_39_M153L,beta-lactamase_39_153,TEM-1,beta-lactamase_39,P62593,0.9732,NO,153,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-3.193,-1.8,-1.393,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.0495842,0.00509109,0.9732 beta-lactamase_2500_I45A,beta-lactamase_2500_45,TEM-1,beta-lactamase_2500,P62593,0.973206,NO,45,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-2.421,-2.001,-0.42,,,E,B,0.48,-0.3,3.793,,77.62,HHA,-2.30267,0.361275,0.00452842,0.973206 beta-lactamase_M127Y,beta-lactamase_127,TEM-1,beta-lactamase,P62593,0.973206,NO,127,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-2.251,-2.954,0.703,5.40552,0.312,S,A,1.07,0.32,1.671,,72.73,PHP,-1.40433,0.221079,0.00437927,0.973206 beta-lactamase_S57W,beta-lactamase_57,TEM-1,beta-lactamase,P62593,0.973206,NO,57,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.918,-5.449,3.531,5.64201,0.352,E,B,0.25,-0.18,1.971,,72.73,APH,-2.29167,0.221079,0.00492804,0.973206 beta-lactamase_39_D33A,beta-lactamase_39_33,TEM-1,beta-lactamase_39,P62593,0.973212,NO,33,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.321,-2.241,-0.08,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.0495842,0.00435556,0.973212 Pab1_D136V,Pab1_136,Pab1,Pab1,P04147,0.97322,NO,136,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.602,-2.315,0.713,,,,,,,,,,OAH,-1.42367,0.175299,0.00227029,0.97322 beta-lactamase_39_A34K,beta-lactamase_39_34,TEM-1,beta-lactamase_39,P62593,0.973221,NO,34,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.059,-3.736,1.677,,,H,A,0.46,-0.54,13.292,13.292,73.78,AHA,-1.74967,0.0495842,0.00407913,0.973221 beta-lactamase_H94A,beta-lactamase_94,TEM-1,beta-lactamase,P62593,0.973232,NO,94,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-2.5,-2.468,-0.032,6.1507,0.776,,B,0.63,1.24,1.176,,77.62,HBH,-1.872,0.221079,0.00389226,0.973232 beta-lactamase_2500_K286T,beta-lactamase_2500_286,TEM-1,beta-lactamase_2500,P62593,0.973234,NO,286,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.361275,,0.973234 beta-lactamase_2500_T126G,beta-lactamase_2500_126,TEM-1,beta-lactamase_2500,P62593,0.973236,NO,126,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.122,-2.22,1.098,,0.05,H,A,0.22,-0.05,0.817,,44.41,HPH,-1.60467,0.361275,0.00244552,0.973236 beta-lactamase_C75C,beta-lactamase_75,TEM-1,beta-lactamase,P62593,0.973237,NO,75,C,C,CC,Special,Special,5.07,5.07,0,0,121,121,0,108.5,108.5,0,-1.245,-1.245,,4.88171,,H,A,0.25,-0.87,0.876,,50,HOO,-1.24333,0.221079,0.0034616,0.973237 beta-lactamase_39_Y103A,beta-lactamase_39_103,TEM-1,beta-lactamase_39,P62593,0.973239,NO,103,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-1.33,-3.426,2.096,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.0495842,0.00443048,0.973239 beta-lactamase_0_E169L,beta-lactamase_0_169,TEM-1,beta-lactamase_0,P62593,0.973241,NO,169,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.23,-3.533,2.303,,0.337,,A,1.04,1,3.516,,73.08,PAH,-1.16533,0.0500837,0.00400994,0.973241 kka2_1:8_L184C,kka2_1:8_184,Kka2,kka2_1:8,P00552,0.973257,NO,184,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.496,-5.02,3.524,,0.489,E,B,0.55,-0.06,4.495,,63.26,AHH,-1.24833,0.100394,0.00518742,0.973257 kka2_1:8_L184C,kka2_1:8_184,Kka2,kka2_1:8,P00552,0.973257,NO,184,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.496,-5.02,3.524,,0.489,E,B,0.55,-0.06,4.495,,63.26,AHH,-1.24833,0.100394,0.00518742,0.973257 beta-lactamase_39_A77F,beta-lactamase_39_77,TEM-1,beta-lactamase_39,P62593,0.973258,NO,77,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.234,-4.125,2.891,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.0495842,0.00282362,0.973258 kka2_1:8_K112I,kka2_1:8_112,Kka2,kka2_1:8,P00552,0.973258,NO,112,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-2.491,-2.233,-0.258,,0.076,H,A,1.3,-1.37,10.58,10.58,56.06,ABH,-2.00133,0.100394,0.00645389,0.973258 kka2_1:8_K112I,kka2_1:8_112,Kka2,kka2_1:8,P00552,0.973258,NO,112,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-2.491,-2.233,-0.258,,0.076,H,A,1.3,-1.37,10.58,10.58,56.06,ABH,-2.00133,0.100394,0.00645389,0.973258 kka2_1:4_P12M,kka2_1:4_12,Kka2,kka2_1:4,P00552,0.973259,NO,12,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.853,-4.703,3.85,,,,B,0.52,1.25,0.843,,48.11,POH,-1.80767,0.168804,0.00500011,0.973259 beta-lactamase_39_T112Q,beta-lactamase_39_112,TEM-1,beta-lactamase_39,P62593,0.973271,NO,112,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.186,-3.981,1.795,,0.921,T,A,0.22,1.06,2.87,,73.78,HPA,-1.925,0.0495842,0.00531334,0.973271 beta-lactamase_625_L191A,beta-lactamase_625_191,TEM-1,beta-lactamase_625,P62593,0.973271,NO,191,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.087,-2.236,1.149,,,H,A,0.55,0.09,1.908,,63.29,BHH,-1.445,0.213352,0.00263549,0.973271 beta-lactamase_156_A40W,beta-lactamase_156_40,TEM-1,beta-lactamase_156,P62593,0.973274,NO,40,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.402,-5.298,3.896,,0.155,S,B,0.46,0.21,1.357,,73.78,OHB,-1.40267,0.111618,0.00490026,0.973274 beta-lactamase_39_V42T,beta-lactamase_39_42,TEM-1,beta-lactamase_39,P62593,0.97328,NO,42,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.564,-3.48,1.916,,0.017,E,B,0.44,-0.51,1.86,,63.99,BHO,-1.042,0.0495842,0.00404515,0.97328 beta-lactamase_A235G,beta-lactamase_235,TEM-1,beta-lactamase,P62593,0.973285,NO,235,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.266,-2.075,0.809,4.83024,0.32,E,B,0.52,-0.86,1.344,,50,OHO,-0.89,0.221079,0.00493474,0.973285 beta-lactamase_39_D271C,beta-lactamase_39_271,TEM-1,beta-lactamase_39,P62593,0.973286,NO,271,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.0495842,0.00752082,0.973286 beta-lactamase_39_D252H,beta-lactamase_39_252,TEM-1,beta-lactamase_39,P62593,0.973291,NO,252,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.0495842,0.00575769,0.973291 beta-lactamase_L137M,beta-lactamase_137,TEM-1,beta-lactamase,P62593,0.973297,NO,137,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.03,-2.58,1.55,5.20117,,H,A,1.07,-0.38,0.674,,42.31,HHP,-1.58933,0.221079,0.00278599,0.973297 beta-lactamase_625_I125M,beta-lactamase_625_125,TEM-1,beta-lactamase_625,P62593,0.973318,NO,125,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.441,-2.597,1.156,,,H,A,0.48,-0.7,2.034,,63.29,HHP,-1.248,0.213352,0.00383964,0.973318 beta-lactamase_2500_S96Y,beta-lactamase_2500_96,TEM-1,beta-lactamase_2500,P62593,0.973322,NO,96,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.27,-4.345,2.075,,0.368,,b,0.27,0.39,32.348,32.348,73.78,HPP,-2.019,0.361275,0.00551835,0.973322 kka2_1:2_A65T,kka2_1:2_65,Kka2,kka2_1:2,P00552,0.973329,NO,65,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.744,-2.824,1.08,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.295029,0.00709258,0.973329 beta-lactamase_156_P143H,beta-lactamase_156_143,TEM-1,beta-lactamase_156,P62593,0.973341,NO,143,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.967,-4.789,3.822,,0.075,H,A,0.52,-0.37,0.479,,66.78,OOB,-1.354,0.111618,0.00114551,0.973341 beta-lactamase_156_L100I,beta-lactamase_156_100,TEM-1,beta-lactamase_156,P62593,0.973346,NO,100,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.218,-1.863,0.645,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.111618,0.00413885,0.973346 beta-lactamase_625_D33V,beta-lactamase_625_33,TEM-1,beta-lactamase_625,P62593,0.973346,NO,33,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.321,-3.488,1.167,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.213352,0.00435556,0.973346 beta-lactamase_156_A40T,beta-lactamase_156_40,TEM-1,beta-lactamase_156,P62593,0.97335,NO,40,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.402,-2.653,1.251,,0.155,S,B,0.46,0.21,1.357,,73.78,OHB,-1.40267,0.111618,0.00490026,0.97335 kka2_1:8_A64C,kka2_1:8_64,Kka2,kka2_1:8,P00552,0.973352,NO,64,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.496,-4.794,3.298,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.100394,0.00705578,0.973352 kka2_1:8_A64C,kka2_1:8_64,Kka2,kka2_1:8,P00552,0.973352,NO,64,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.496,-4.794,3.298,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.100394,0.00705578,0.973352 beta-lactamase_A133T,beta-lactamase_133,TEM-1,beta-lactamase,P62593,0.973369,NO,133,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.186,-2.382,1.196,4.86423,,H,A,0.55,-0.86,2.649,,67.83,HHP,-0.988333,0.221079,0.00468022,0.973369 beta-lactamase_E195K,beta-lactamase_195,TEM-1,beta-lactamase,P62593,0.973369,NO,195,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.186,-2.529,0.343,7.28489,1.016,S,A,1.52,0.85,2.583,,77.62,OAH,-2.02,0.221079,0.00496565,0.973369 beta-lactamase_0_N50I,beta-lactamase_0_50,TEM-1,beta-lactamase_0,P62593,0.973372,NO,50,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-2.979,-3.889,0.91,,0.912,T,A,0.61,1.24,9.874,9.874,77.62,HPP,-2.134,0.0500837,0.0047211,0.973372 beta-lactamase_2500_R91H,beta-lactamase_2500_91,TEM-1,beta-lactamase_2500,P62593,0.973372,NO,91,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.392,-4.422,3.03,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.361275,0.00380226,0.973372 beta-lactamase_2500_D207Y,beta-lactamase_2500_207,TEM-1,beta-lactamase_2500,P62593,0.97338,NO,207,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.064,-4.317,2.253,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.361275,0.00592942,0.97338 beta-lactamase_2500_R202A,beta-lactamase_2500_202,TEM-1,beta-lactamase_2500,P62593,0.97338,NO,202,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.292,-2.462,1.17,,0.188,H,A,1.2,0.62,3.734,,77.62,PBP,-1.54767,0.361275,0.00321899,0.97338 beta-lactamase_39_V101S,beta-lactamase_39_101,TEM-1,beta-lactamase_39,P62593,0.973387,NO,101,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.295,-3.65,2.355,,0.342,,B,0.44,0,2.96,,73.08,HHA,-1.54367,0.0495842,0.00374492,0.973387 beta-lactamase_156_P165I,beta-lactamase_156_165,TEM-1,beta-lactamase_156,P62593,0.973393,NO,165,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.373,-3.815,2.442,,0.203,T,A,0.52,-0.31,3.907,,73.78,AOA,-1.359,0.111618,0.00549538,0.973393 beta-lactamase_156_H151D,beta-lactamase_156_151,TEM-1,beta-lactamase_156,P62593,0.973395,NO,151,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-2.96,-3.624,0.664,,0.594,H,A,0.17,0.1,1.401,,77.62,HBP,-2.34767,0.111618,0.00216946,0.973395 beta-lactamase_156_R41K,beta-lactamase_156_41,TEM-1,beta-lactamase_156,P62593,0.9734,NO,41,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-0.942,-2.85,1.908,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.111618,0.00123327,0.9734 beta-lactamase_156_S201I,beta-lactamase_156_201,TEM-1,beta-lactamase_156,P62593,0.973401,NO,201,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.183,-3.765,2.582,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.111618,0.00198815,0.973401 beta-lactamase_156_A268H,beta-lactamase_156_268,TEM-1,beta-lactamase_156,P62593,0.973405,NO,268,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.111618,0.0102525,0.973405 beta-lactamase_39_E61L,beta-lactamase_39_61,TEM-1,beta-lactamase_39,P62593,0.973406,NO,61,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.115,-3.769,1.654,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.0495842,0.00440955,0.973406 beta-lactamase_625_F70Q,beta-lactamase_625_70,TEM-1,beta-lactamase_625,P62593,0.973409,NO,70,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.169,-4.201,3.032,,,H,A,0.58,-1.34,1.14,,63.99,PHB,-0.980667,0.213352,0.00193499,0.973409 beta-lactamase_A230A,beta-lactamase_230,TEM-1,beta-lactamase,P62593,0.973426,NO,230,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.154,-1.154,,4.54336,0.01,E,B,0.75,-1.17,1.97,,50,HHA,-1.079,0.221079,0.00516841,0.973426 beta-lactamase_2500_Q97Y,beta-lactamase_2500_97,TEM-1,beta-lactamase_2500,P62593,0.973436,NO,97,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.072,-4.35,2.278,,0.823,G,A,0.64,2.42,1.157,,77.62,PPP,-2.43833,0.361275,0.0045116,0.973436 WW_domain_Q200W,WW_domain_200,Yap65,WW_domain,P46937,0.973438,NO,200,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-1.599,-5.08,3.481,5.37476,,,,,,1.9,,70.04,HPA,-1.484,0.153962,0.00300397,0.973438 beta-lactamase_156_A123H,beta-lactamase_156_123,TEM-1,beta-lactamase_156,P62593,0.973439,NO,123,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.834,-4.729,3.895,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.111618,0.0010157,0.973439 beta-lactamase_A84A,beta-lactamase_84,TEM-1,beta-lactamase,P62593,0.973448,NO,84,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.651,-1.651,,5.28927,0.65,T,A,0.52,0.96,1.863,,68.18,AHO,-1.24267,0.221079,0.00503822,0.973448 beta-lactamase_625_T139F,beta-lactamase_625_139,TEM-1,beta-lactamase_625,P62593,0.973457,NO,139,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.901,-4.292,2.391,,0.216,H,A,0.22,0.39,2.256,,77.62,PPH,-2.04667,0.213352,0.00441837,0.973457 beta-lactamase_39_L28C,beta-lactamase_39_28,TEM-1,beta-lactamase_39,P62593,0.973468,NO,28,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.579,-4.763,3.184,,0.277,H,A,0.55,-0.16,3.262,,93.01,PHH,-2.11333,0.0495842,0.00359321,0.973468 beta-lactamase_156_I125N,beta-lactamase_156_125,TEM-1,beta-lactamase_156,P62593,0.973474,NO,125,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.441,-4.089,2.648,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.111618,0.00383964,0.973474 beta-lactamase_39_R159N,beta-lactamase_39_159,TEM-1,beta-lactamase_39,P62593,0.97349,NO,159,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-0.94,-3.445,2.505,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.0495842,0.00108472,0.97349 beta-lactamase_39_D271G,beta-lactamase_39_271,TEM-1,beta-lactamase_39,P62593,0.973496,NO,271,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.0495842,0.00752082,0.973496 kka2_1:4_G210A,kka2_1:4_210,Kka2,kka2_1:4,P00552,0.973503,NO,210,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.095,-2.003,0.908,,0.103,T,A,0.29,-0.62,0.271,,50,OOB,-0.966667,0.168804,0.00598378,0.973503 beta-lactamase_39_L89C,beta-lactamase_39_89,TEM-1,beta-lactamase_39,P62593,0.973508,NO,89,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.096,-4.756,3.66,,0.168,T,A,0.55,0.63,3.233,,64.34,PHO,-1.75767,0.0495842,0.00207068,0.973508 kka2_1:8_I115A,kka2_1:8_115,Kka2,kka2_1:8,P00552,0.973512,NO,115,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.606,-2.706,1.1,,0.105,H,A,1.52,-1.18,4.064,,65.53,PHH,-2.205,0.100394,0.00836567,0.973512 kka2_1:8_I115A,kka2_1:8_115,Kka2,kka2_1:8,P00552,0.973512,NO,115,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.606,-2.706,1.1,,0.105,H,A,1.52,-1.18,4.064,,65.53,PHH,-2.205,0.100394,0.00836567,0.973512 beta-lactamase_156_M153G,beta-lactamase_156_153,TEM-1,beta-lactamase_156,P62593,0.973516,NO,153,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-3.193,-3.633,0.44,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.111618,0.00509109,0.973516 PSD95pdz3_G383R,PSD95pdz3_383,PSD95pdz3,PSD95pdz3,P31016,0.973516,NO,383,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.008,-3.615,2.607,5.17213,,,,,20.5325,,,,HOP,-1.338,0.0758425,0.000233044,0.973516 beta-lactamase_156_P143I,beta-lactamase_156_143,TEM-1,beta-lactamase_156,P62593,0.973519,NO,143,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.967,-2.787,1.82,,0.075,H,A,0.52,-0.37,0.479,,66.78,OOB,-1.354,0.111618,0.00114551,0.973519 beta-lactamase_0_L100Q,beta-lactamase_0_100,TEM-1,beta-lactamase_0,P62593,0.97352,NO,100,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.218,-4.259,3.041,,0.343,,B,0.55,0.13,1.373,,63.29,AHH,-1.23467,0.0500837,0.00413885,0.97352 kka2_1:8_P132H,kka2_1:8_132,Kka2,kka2_1:8,P00552,0.973521,NO,132,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.775,-4.706,3.931,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.100394,0.0018489,0.973521 kka2_1:8_P132H,kka2_1:8_132,Kka2,kka2_1:8,P00552,0.973521,NO,132,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.775,-4.706,3.931,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.100394,0.0018489,0.973521 beta-lactamase_156_V101D,beta-lactamase_156_101,TEM-1,beta-lactamase_156,P62593,0.973544,NO,101,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.295,-2.887,1.592,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.111618,0.00374492,0.973544 beta-lactamase_39_A148M,beta-lactamase_39_148,TEM-1,beta-lactamase_39,P62593,0.973544,NO,148,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.757,-4.798,3.041,,0.379,H,A,0.46,-0.55,3.551,,72.73,PHH,-1.40167,0.0495842,0.00547053,0.973544 beta-lactamase_G90Q,beta-lactamase_90,TEM-1,beta-lactamase,P62593,0.973546,NO,90,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-2.091,-2.862,0.771,5.51991,0.598,T,A,0.23,0.32,1.791,,77.62,HOB,-1.52633,0.221079,0.00490273,0.973546 beta-lactamase_625_R159E,beta-lactamase_625_159,TEM-1,beta-lactamase_625,P62593,0.973563,NO,159,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-0.94,-3.241,2.301,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.213352,0.00108472,0.973563 beta-lactamase_2500_T107A,beta-lactamase_2500_107,TEM-1,beta-lactamase_2500,P62593,0.973571,NO,107,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.117,-2.274,1.157,,,G,A,0.22,-0.06,2.686,,67.83,HPA,-1.265,0.361275,0.00239347,0.973571 beta-lactamase_156_P217F,beta-lactamase_156_217,TEM-1,beta-lactamase_156,P62593,0.973592,NO,217,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-2.062,-4.432,2.37,,0.496,I,A,0.52,-0.33,2.303,,74.48,OOH,-1.64333,0.111618,0.00463211,0.973592 beta-lactamase_156_L197Q,beta-lactamase_156_197,TEM-1,beta-lactamase_156,P62593,0.973603,NO,197,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.853,-4.122,3.269,,0.007,S,B,0.55,0.33,1.58,,60.14,HHP,-1.833,0.111618,0.00144602,0.973603 beta-lactamase_39_G142P,beta-lactamase_39_142,TEM-1,beta-lactamase_39,P62593,0.973617,NO,142,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.707,-3.877,3.17,,0.034,,p,0.29,-0.64,1.947,,64.69,OOO,-0.834,0.0495842,0.00060149,0.973617 beta-lactamase_2500_S256M,beta-lactamase_2500_256,TEM-1,beta-lactamase_2500,P62593,0.973622,NO,256,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.361275,0.00710634,0.973622 beta-lactamase_I243L,beta-lactamase_243,TEM-1,beta-lactamase,P62593,0.97364,NO,243,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.532,-2.296,0.764,5.26886,,E,B,1.68,-1.24,2.289,,50,OHH,-1.46867,0.221079,0.00464034,0.97364 beta-lactamase_V117L,beta-lactamase_117,TEM-1,beta-lactamase,P62593,0.97364,NO,117,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.53,-1.606,0.076,5.33594,,H,A,1.19,-0.34,1.182,,65.03,PHB,-1.741,0.221079,0.00467906,0.97364 beta-lactamase_156_D48K,beta-lactamase_156_48,TEM-1,beta-lactamase_156,P62593,0.973644,NO,48,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.101,-3.448,2.347,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.111618,0.0027273,0.973644 beta-lactamase_2500_G194K,beta-lactamase_2500_194,TEM-1,beta-lactamase_2500,P62593,0.973644,NO,194,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.396,-3.557,2.161,,0.276,S,b,0.29,0.36,3.593,,67.83,POA,-1.832,0.361275,0.00392163,0.973644 beta-lactamase_39_A222E,beta-lactamase_39_222,TEM-1,beta-lactamase_39,P62593,0.973647,NO,222,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.103,-3.646,1.543,,0.233,H,A,0.46,-0.25,1.448,,77.62,PHH,-1.63733,0.0495842,0.00466094,0.973647 beta-lactamase_39_Y262W,beta-lactamase_39_262,TEM-1,beta-lactamase_39,P62593,0.973651,NO,262,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.0495842,0.00853516,0.973651 beta-lactamase_156_G216K,beta-lactamase_156_216,TEM-1,beta-lactamase_156,P62593,0.973657,NO,216,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.477,-2.765,1.288,,0.437,I,A,0.29,-0.58,12.464,12.464,74.48,HOO,-1.68067,0.111618,0.00639568,0.973657 beta-lactamase_156_H151K,beta-lactamase_156_151,TEM-1,beta-lactamase_156,P62593,0.973659,NO,151,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-2.96,-3.032,0.072,,0.594,H,A,0.17,0.1,1.401,,77.62,HBP,-2.34767,0.111618,0.00216946,0.973659 gb1_T281K,gb1_281,gb1,gb1,P06654,0.973659,NO,281,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.828,-3.106,1.278,,,,,,,1.038,,35.71,HPA,-1.63667,0.177985,0.00284418,0.973659 beta-lactamase_2500_P172L,beta-lactamase_2500_172,TEM-1,beta-lactamase_2500,P62593,0.973664,NO,172,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.998,-2.658,1.66,,0.639,T,b,0.52,0.24,4.99,,74.48,HOP,-2.03067,0.361275,0.00312594,0.973664 beta-lactamase_625_L49C,beta-lactamase_625_49,TEM-1,beta-lactamase_625,P62593,0.973677,NO,49,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.897,-4.929,3.032,,0.131,T,A,0.55,0.04,3.112,,64.69,AHP,-1.99233,0.213352,0.00401477,0.973677 Pab1_I128V,Pab1_128,Pab1,Pab1,P04147,0.973679,NO,128,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.345,-1.656,0.311,,0.008,E,B,1.68,-0.6,1.706,,78.68,PHH,-1.231,0.175299,0.00104192,0.973679 beta-lactamase_39_L218F,beta-lactamase_39_218,TEM-1,beta-lactamase_39,P62593,0.97368,NO,218,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.391,-2.985,1.594,,,I,b,0.55,-0.53,2.038,,74.48,OHH,-1.58867,0.0495842,0.00618274,0.97368 beta-lactamase_0_L73A,beta-lactamase_0_73,TEM-1,beta-lactamase_0,P62593,0.973706,NO,73,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.507,-2.475,0.968,,,H,A,0.55,-0.64,0.877,,67.83,HHH,-1.487,0.0500837,0.00488983,0.973706 beta-lactamase_2500_T198N,beta-lactamase_2500_198,TEM-1,beta-lactamase_2500,P62593,0.973707,NO,198,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.168,-3.569,1.401,,0.489,,B,0.22,-0.13,0.37,,73.78,HPH,-1.98767,0.361275,0.004311,0.973707 Pab1_E176K,Pab1_176,Pab1,Pab1,P04147,0.973707,NO,176,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.003,-3.364,1.361,,,,,,,,,,AAO,-2.09933,0.175299,0.00264426,0.973707 kka2_1:8_L184W,kka2_1:8_184,Kka2,kka2_1:8,P00552,0.97371,NO,184,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.496,-3.533,2.037,,0.489,E,B,0.55,-0.06,4.495,,63.26,AHH,-1.24833,0.100394,0.00518742,0.97371 kka2_1:8_L184W,kka2_1:8_184,Kka2,kka2_1:8,P00552,0.97371,NO,184,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.496,-3.533,2.037,,0.489,E,B,0.55,-0.06,4.495,,63.26,AHH,-1.24833,0.100394,0.00518742,0.97371 beta-lactamase_39_A278I,beta-lactamase_39_278,TEM-1,beta-lactamase_39,P62593,0.973728,NO,278,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.348,-3.123,1.775,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.0495842,0.0310297,0.973728 Pab1_G163S,Pab1_163,Pab1,Pab1,P04147,0.973729,NO,163,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.809,-2.978,2.169,,0.356,B,g,,0.55,,,,POB,-1.80667,0.175299,0.00030953,0.973729 beta-lactamase_156_S51H,beta-lactamase_156_51,TEM-1,beta-lactamase_156,P62593,0.973732,NO,51,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.526,-4.622,3.096,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.111618,0.00504821,0.973732 beta-lactamase_F13I,beta-lactamase_13,TEM-1,beta-lactamase,P62593,0.973739,NO,13,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-2.394,-2.505,0.111,,,,,,,4.079,,77.62,OHH,-2.382,0.221079,0.0029078,0.973739 beta-lactamase_G194P,beta-lactamase_194,TEM-1,beta-lactamase,P62593,0.973739,NO,194,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.396,-3.912,2.516,5.46622,0.276,S,b,0.77,0.36,3.593,,67.83,POA,-1.832,0.221079,0.00392163,0.973739 beta-lactamase_N98D,beta-lactamase_98,TEM-1,beta-lactamase,P62593,0.973739,NO,98,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-2.973,-2.35,-0.623,6.59973,0.963,G,A,1.07,1.35,1.332,,77.62,PPA,-2.07867,0.221079,0.00505389,0.973739 beta-lactamase_R7P,beta-lactamase_7,TEM-1,beta-lactamase,P62593,0.973739,NO,7,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.683,-3.936,2.253,,,,,,,2.44,,67.13,HBH,-1.96267,0.221079,0.00211375,0.973739 beta-lactamase_S80V,beta-lactamase_80,TEM-1,beta-lactamase,P62593,0.973739,NO,80,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.029,-2.695,0.666,5.23748,0.192,H,A,0.25,0.46,2.256,,77.62,HPB,-1.44567,0.221079,0.00565569,0.973739 beta-lactamase_T267R,beta-lactamase_267,TEM-1,beta-lactamase,P62593,0.973739,NO,267,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.308,-3.901,1.593,5.28263,0.54,,B,0.69,-0.14,0.374,,73.78,HPH,-1.9,0.221079,0.0102128,0.973739 beta-lactamase_39_E56I,beta-lactamase_39_56,TEM-1,beta-lactamase_39,P62593,0.973744,NO,56,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.043,-3.825,1.782,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.0495842,0.00238534,0.973744 beta-lactamase_625_D33N,beta-lactamase_625_33,TEM-1,beta-lactamase_625,P62593,0.973745,NO,33,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.321,-2.983,0.662,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.213352,0.00435556,0.973745 beta-lactamase_39_R273K,beta-lactamase_39_273,TEM-1,beta-lactamase_39,P62593,0.973752,NO,273,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.314,-2.204,-0.11,,0.564,H,A,1.2,1.57,2.163,,73.78,ABP,-1.841,0.0495842,0.0077952,0.973752 beta-lactamase_0_S283E,beta-lactamase_0_283,TEM-1,beta-lactamase_0,P62593,0.973756,NO,283,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.0500837,0.0429138,0.973756 beta-lactamase_0_I261L,beta-lactamase_0_261,TEM-1,beta-lactamase_0,P62593,0.973758,NO,261,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.0500837,0.0123091,0.973758 beta-lactamase_625_T264N,beta-lactamase_625_264,TEM-1,beta-lactamase_625,P62593,0.973758,NO,264,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.213352,0.0119399,0.973758 beta-lactamase_156_D113R,beta-lactamase_156_113,TEM-1,beta-lactamase_156,P62593,0.973761,NO,113,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.829,-2.854,1.025,,0.665,T,A,0.75,0.91,2.973,,73.08,PAO,-1.703,0.111618,0.00474112,0.973761 beta-lactamase_L10L,beta-lactamase_10,TEM-1,beta-lactamase,P62593,0.973764,NO,10,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.623,-1.623,,,,,,,,2.467,,65.38,HHH,-1.83833,0.221079,0.00296968,0.973764 kka2_1:2_T28Y,kka2_1:2_28,Kka2,kka2_1:2,P00552,0.973775,NO,28,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.883,-4.4,2.517,,0.353,S,B,0.22,2.02,2.655,,63.64,PPH,-1.74467,0.295029,0.00743084,0.973775 beta-lactamase_2500_A278Y,beta-lactamase_2500_278,TEM-1,beta-lactamase_2500,P62593,0.973782,NO,278,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.361275,0.0310297,0.973782 beta-lactamase_625_E62N,beta-lactamase_625_62,TEM-1,beta-lactamase_625,P62593,0.973788,NO,62,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.193,-3.541,2.348,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.213352,0.00264802,0.973788 beta-lactamase_2500_I285M,beta-lactamase_2500_285,TEM-1,beta-lactamase_2500,P62593,0.973793,NO,285,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.361275,0.101555,0.973793 beta-lactamase_625_D252L,beta-lactamase_625_252,TEM-1,beta-lactamase_625,P62593,0.973796,NO,252,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.213352,0.00575769,0.973796 kka2_1:2_D23M,kka2_1:2_23,Kka2,kka2_1:2,P00552,0.973796,NO,23,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.459,-4.807,2.348,,0.695,E,B,0.75,-0.65,18.207,18.207,65.53,HAH,-1.94033,0.295029,0.007195,0.973796 kka2_1:8_P132V,kka2_1:8_132,Kka2,kka2_1:8,P00552,0.973815,NO,132,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.775,-3.58,2.805,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.100394,0.0018489,0.973815 kka2_1:8_P132V,kka2_1:8_132,Kka2,kka2_1:8,P00552,0.973815,NO,132,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.775,-3.58,2.805,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.100394,0.0018489,0.973815 beta-lactamase_2500_G85E,beta-lactamase_2500_85,TEM-1,beta-lactamase_2500,P62593,0.973816,NO,85,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.011,-3.408,2.397,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.361275,0.00252173,0.973816 PSD95pdz3_V386C,PSD95pdz3_386,PSD95pdz3,PSD95pdz3,P31016,0.973816,NO,386,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.465,-4.319,2.854,5.18836,,,,,17.5429,,,,PHP,-1.463,0.0758425,0.000184509,0.973816 beta-lactamase_2500_I261L,beta-lactamase_2500_261,TEM-1,beta-lactamase_2500,P62593,0.973817,NO,261,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.361275,0.0123091,0.973817 beta-lactamase_156_M153H,beta-lactamase_156_153,TEM-1,beta-lactamase_156,P62593,0.973821,NO,153,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-3.193,-4.946,1.753,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.111618,0.00509109,0.973821 beta-lactamase_39_P165N,beta-lactamase_39_165,TEM-1,beta-lactamase_39,P62593,0.973827,NO,165,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.373,-3.703,2.33,,0.203,T,A,0.52,-0.31,3.907,,73.78,AOA,-1.359,0.0495842,0.00549538,0.973827 beta-lactamase_39_H24Y,beta-lactamase_39_24,TEM-1,beta-lactamase_39,P62593,0.973829,NO,24,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-2.481,-4.052,1.571,,,,,,,2.708,,93.01,OBO,-2.0035,0.0495842,0.00238894,0.973829 beta-lactamase_2500_V31L,beta-lactamase_2500_31,TEM-1,beta-lactamase_2500,P62593,0.97383,NO,31,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.822,-2.16,0.338,,,H,A,0.44,-0.46,0.955,,73.78,BHB,-2.03767,0.361275,0.00478065,0.97383 beta-lactamase_625_S57M,beta-lactamase_625_57,TEM-1,beta-lactamase_625,P62593,0.973837,NO,57,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.918,-4.684,2.766,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.213352,0.00492804,0.973837 PSD95pdz3_T387E,PSD95pdz3_387,PSD95pdz3,PSD95pdz3,P31016,0.973838,NO,387,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.391,-3.122,1.731,5.20757,,,,,18.8043,,,,HPH,-1.49533,0.0758425,0.000167911,0.973838 beta-lactamase_E87I,beta-lactamase_87,TEM-1,beta-lactamase,P62593,0.973842,NO,87,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.421,-3.687,2.266,5.41929,0.048,,B,0.52,0.92,1.754,,64.69,PAP,-1.969,0.221079,0.00337888,0.973842 beta-lactamase_39_V78G,beta-lactamase_39_78,TEM-1,beta-lactamase_39,P62593,0.973865,NO,78,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.459,-2.817,1.358,,,H,A,0.44,-0.47,1.132,,63.64,HHH,-1.17833,0.0495842,0.00492501,0.973865 beta-lactamase_G251D,beta-lactamase_251,TEM-1,beta-lactamase,P62593,0.973896,NO,251,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.907,-2.527,0.62,5.33865,0.506,T,l,0.73,0.17,10.663,,65.38,AOB,-2.06067,0.221079,0.00733416,0.973896 beta-lactamase_156_D113W,beta-lactamase_156_113,TEM-1,beta-lactamase_156,P62593,0.973899,NO,113,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.829,-5.545,3.716,,0.665,T,A,0.75,0.91,2.973,,73.08,PAO,-1.703,0.111618,0.00474112,0.973899 PSD95pdz3_I336Q,PSD95pdz3_336,PSD95pdz3,PSD95pdz3,P31016,0.973903,NO,336,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.63,-4.031,2.401,5.11321,,,,,13.6363,,,,OHH,-1.38733,0.0758425,0.000887923,0.973903 beta-lactamase_625_F228M,beta-lactamase_625_228,TEM-1,beta-lactamase_625,P62593,0.973911,NO,228,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-2.342,-3.369,1.027,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.213352,0.0046669,0.973911 beta-lactamase_156_T116I,beta-lactamase_156_116,TEM-1,beta-lactamase_156,P62593,0.973921,NO,116,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.28,-3.822,2.542,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.111618,0.00336175,0.973921 kka2_1:1_A247T,kka2_1:1_247,Kka2,kka2_1:1,P00552,0.973922,NO,247,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.459,-2.783,0.324,,1.01,S,A,0.46,0.65,7.731,7.731,92.05,HHH,-2.197,0.520039,0.0102428,0.973922 beta-lactamase_2500_A278F,beta-lactamase_2500_278,TEM-1,beta-lactamase_2500,P62593,0.973929,NO,278,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.361275,0.0310297,0.973929 beta-lactamase_625_K213G,beta-lactamase_625_213,TEM-1,beta-lactamase_625,P62593,0.973929,NO,213,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.81,-2.317,0.507,,0.67,,A,2.34,0.29,3.924,,67.83,ABH,-1.57767,0.213352,0.00610411,0.973929 beta-lactamase_0_L100I,beta-lactamase_0_100,TEM-1,beta-lactamase_0,P62593,0.97393,NO,100,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.218,-1.863,0.645,,0.343,,B,0.55,0.13,1.373,,63.29,AHH,-1.23467,0.0500837,0.00413885,0.97393 beta-lactamase_156_V101Q,beta-lactamase_156_101,TEM-1,beta-lactamase_156,P62593,0.973939,NO,101,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.295,-4.106,2.811,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.111618,0.00374492,0.973939 beta-lactamase_39_E102M,beta-lactamase_39_102,TEM-1,beta-lactamase_39,P62593,0.973941,NO,102,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.118,-4.799,2.681,,0.722,S,B,1.04,1.82,3.87,,73.08,HAH,-1.581,0.0495842,0.00486633,0.973941 beta-lactamase_156_Q204R,beta-lactamase_156_204,TEM-1,beta-lactamase_156,P62593,0.973947,NO,204,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-1.382,-2.322,0.94,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.111618,0.00364106,0.973947 beta-lactamase_E169Y,beta-lactamase_169,TEM-1,beta-lactamase,P62593,0.97395,NO,169,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.23,-4.247,3.017,5.78896,0.337,,A,0.52,1,1.806,,73.08,PAH,-1.16533,0.221079,0.00400994,0.97395 beta-lactamase_G39C,beta-lactamase_39,TEM-1,beta-lactamase,P62593,0.97395,NO,39,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.864,-5.191,3.327,5.35574,0.701,T,L,0.23,0.47,29.926,29.926,77.62,HOH,-1.53633,0.221079,0.00487611,0.97395 beta-lactamase_G76S,beta-lactamase_76,TEM-1,beta-lactamase,P62593,0.97395,NO,76,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.189,-2.528,1.339,4.73862,,H,A,2.05,-0.67,3.059,,67.83,OOH,-1.22267,0.221079,0.00476637,0.97395 beta-lactamase_39_T264K,beta-lactamase_39_264,TEM-1,beta-lactamase_39,P62593,0.973954,NO,264,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.0495842,0.0119399,0.973954 kka2_1:8_G43C,kka2_1:8_43,Kka2,kka2_1:8,P00552,0.973957,NO,43,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.587,-3.529,1.942,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.100394,0.0071925,0.973957 kka2_1:8_G43C,kka2_1:8_43,Kka2,kka2_1:8,P00552,0.973957,NO,43,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.587,-3.529,1.942,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.100394,0.0071925,0.973957 beta-lactamase_2500_H156G,beta-lactamase_2500_156,TEM-1,beta-lactamase_2500,P62593,0.973958,NO,156,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-3.156,-2.688,-0.468,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.361275,0.00468596,0.973958 beta-lactamase_0_E62D,beta-lactamase_0_62,TEM-1,beta-lactamase_0,P62593,0.973963,NO,62,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.193,-2.088,0.895,,0.342,S,B,1.04,-0.3,5.784,,73.08,AAB,-1.417,0.0500837,0.00264802,0.973963 beta-lactamase_39_I125F,beta-lactamase_39_125,TEM-1,beta-lactamase_39,P62593,0.973971,NO,125,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.441,-3.841,2.4,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.0495842,0.00383964,0.973971 beta-lactamase_39_E56W,beta-lactamase_39_56,TEM-1,beta-lactamase_39,P62593,0.973983,NO,56,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.043,-5.293,3.25,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.0495842,0.00238534,0.973983 beta-lactamase_39_V117N,beta-lactamase_39_117,TEM-1,beta-lactamase_39,P62593,0.973994,NO,117,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.53,-4.224,2.694,,,H,A,0.44,-0.34,1.182,,65.03,PHB,-1.741,0.0495842,0.00467906,0.973994 kka2_1:8_W91H,kka2_1:8_91,Kka2,kka2_1:8,P00552,0.973994,NO,91,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-1.178,-4.573,3.395,,0.077,E,B,1.51,0.27,2.51,,48.48,AHH,-1.51,0.100394,0.00358653,0.973994 kka2_1:8_W91H,kka2_1:8_91,Kka2,kka2_1:8,P00552,0.973994,NO,91,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-1.178,-4.573,3.395,,0.077,E,B,1.51,0.27,2.51,,48.48,AHH,-1.51,0.100394,0.00358653,0.973994 beta-lactamase_D113G,beta-lactamase_113,TEM-1,beta-lactamase,P62593,0.973995,NO,113,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.829,-2.42,0.591,6.04499,0.665,T,A,0.23,0.91,21.104,21.104,73.08,PAO,-1.703,0.221079,0.00474112,0.973995 beta-lactamase_156_D161E,beta-lactamase_156_161,TEM-1,beta-lactamase_156,P62593,0.974004,NO,161,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.891,-2.299,1.408,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.111618,0.000897697,0.974004 beta-lactamase_156_M115R,beta-lactamase_156_115,TEM-1,beta-lactamase_156,P62593,0.974009,NO,115,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.389,-2.862,1.473,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.111618,0.0034337,0.974009 PSD95pdz3_A390M,PSD95pdz3_390,PSD95pdz3,PSD95pdz3,P31016,0.974021,NO,390,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.307,-4.162,2.855,5.03823,,,,,12.46,,,,HHP,-1.54467,0.0758425,0.00104603,0.974021 beta-lactamase_39_T139I,beta-lactamase_39_139,TEM-1,beta-lactamase_39,P62593,0.974028,NO,139,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.901,-3.075,1.174,,0.216,H,A,0.22,0.39,0.421,,77.62,PPH,-2.04667,0.0495842,0.00441837,0.974028 gb1_L233T,gb1_233,gb1,gb1,P06654,0.974038,NO,233,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-2.678,-3.197,0.519,,,,,,,0.822,,45.54,HHP,-2.30267,0.177985,0.00266958,0.974038 beta-lactamase_156_A225Q,beta-lactamase_156_225,TEM-1,beta-lactamase_156,P62593,0.974039,NO,225,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.845,-2.909,1.064,,1,T,B,0.46,-0.38,11.722,11.722,74.48,OHO,-1.39967,0.111618,0.00465057,0.974039 kka2_1:8_R140Q,kka2_1:8_140,Kka2,kka2_1:8,P00552,0.974046,NO,140,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.351,-2.5,1.149,,0.12,H,A,0.16,0.2,2.874,,53.03,BBH,-1.885,0.100394,0.00430167,0.974046 kka2_1:8_R140Q,kka2_1:8_140,Kka2,kka2_1:8,P00552,0.974046,NO,140,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.351,-2.5,1.149,,0.12,H,A,0.16,0.2,2.874,,53.03,BBH,-1.885,0.100394,0.00430167,0.974046 beta-lactamase_2500_E102F,beta-lactamase_2500_102,TEM-1,beta-lactamase_2500,P62593,0.974047,NO,102,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.118,-4.365,2.247,,0.722,S,B,1.04,1.82,1.336,,73.08,HAH,-1.581,0.361275,0.00486633,0.974047 beta-lactamase_0_R189E,beta-lactamase_0_189,TEM-1,beta-lactamase_0,P62593,0.974048,NO,189,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.844,-2.256,0.412,,0.278,H,A,1.2,1.01,12.11,12.11,72.73,HBB,-1.668,0.0500837,0.0050699,0.974048 beta-lactamase_Q274R,beta-lactamase_274,TEM-1,beta-lactamase,P62593,0.974064,NO,274,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.082,-3.742,1.66,5.6671,0.066,H,A,0.11,-0.27,2.354,,64.69,BPH,-1.931,0.221079,0.0110418,0.974064 beta-lactamase_625_K213R,beta-lactamase_625_213,TEM-1,beta-lactamase_625,P62593,0.974078,NO,213,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.81,-1.968,0.158,,0.67,,A,2.34,0.29,3.924,,67.83,ABH,-1.57767,0.213352,0.00610411,0.974078 beta-lactamase_156_K30Y,beta-lactamase_156_30,TEM-1,beta-lactamase_156,P62593,0.974081,NO,30,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-2.307,-4.255,1.948,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.111618,0.00448593,0.974081 kka2_1:8_P12K,kka2_1:8_12,Kka2,kka2_1:8,P00552,0.974082,NO,12,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.853,-3.495,2.642,,,.,B,0.52,1.25,2.41,,48.11,POH,-1.80767,0.100394,0.00500011,0.974082 kka2_1:8_P12K,kka2_1:8_12,Kka2,kka2_1:8,P00552,0.974082,NO,12,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.853,-3.495,2.642,,,.,B,0.52,1.25,2.41,,48.11,POH,-1.80767,0.100394,0.00500011,0.974082 beta-lactamase_M127L,beta-lactamase_127,TEM-1,beta-lactamase,P62593,0.974114,NO,127,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-2.251,-2.123,-0.128,5.40552,0.312,S,A,1.07,0.32,1.671,,72.73,PHP,-1.40433,0.221079,0.00437927,0.974114 PSD95pdz3_G383M,PSD95pdz3_383,PSD95pdz3,PSD95pdz3,P31016,0.974116,NO,383,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.008,-4.612,3.604,5.17213,,,,,20.5325,,,,HOP,-1.338,0.0758425,0.000233044,0.974116 kka2_1:8_M197Q,kka2_1:8_197,Kka2,kka2_1:8,P00552,0.974117,NO,197,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.707,-4.152,2.445,,0.121,E,B,1.59,-1.19,4.408,,65.53,HHH,-1.847,0.100394,0.00921295,0.974117 kka2_1:8_M197Q,kka2_1:8_197,Kka2,kka2_1:8,P00552,0.974117,NO,197,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.707,-4.152,2.445,,0.121,E,B,1.59,-1.19,4.408,,65.53,HHH,-1.847,0.100394,0.00921295,0.974117 beta-lactamase_E166C,beta-lactamase_166,TEM-1,beta-lactamase,P62593,0.974123,NO,166,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.756,-5.069,3.313,5.60527,0.508,G,A,0.52,1.05,2.124,,73.08,OAH,-1.42233,0.221079,0.00512989,0.974123 Pab1_D184Y,Pab1_184,Pab1,Pab1,P04147,0.974123,NO,184,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.5,-4.145,2.645,,,,,,,,,,HAH,-1.50133,0.175299,0.0011931,0.974123 kka2_1:2_V80L,kka2_1:2_80,Kka2,kka2_1:2,P00552,0.974127,NO,80,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.144,-2.831,1.687,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.295029,0.00488211,0.974127 beta-lactamase_2500_V29Y,beta-lactamase_2500_29,TEM-1,beta-lactamase_2500,P62593,0.974133,NO,29,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-2.856,-4.329,1.473,,0.733,H,A,0.44,-0.78,1.931,,93.01,HHB,-2.24733,0.361275,0.00318969,0.974133 beta-lactamase_156_E102Q,beta-lactamase_156_102,TEM-1,beta-lactamase_156,P62593,0.974135,NO,102,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.118,-3.043,0.925,,0.722,S,B,1.04,1.82,15.721,15.721,73.08,HAH,-1.581,0.111618,0.00486633,0.974135 beta-lactamase_V82C,beta-lactamase_82,TEM-1,beta-lactamase,P62593,0.974148,NO,82,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.325,-4.774,3.449,5.27777,0.267,H,A,0.96,0.08,1.379,,93.01,BHA,-1.28567,0.221079,0.00397046,0.974148 beta-lactamase_156_T187E,beta-lactamase_156_187,TEM-1,beta-lactamase_156,P62593,0.974161,NO,187,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.401,-3.52,2.119,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.111618,0.00491782,0.974161 kka2_1:2_D154K,kka2_1:2_154,Kka2,kka2_1:2,P00552,0.974163,NO,154,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.876,-3.46,2.584,,0.457,,b,0.29,1.48,3.631,,52.65,HAP,-1.52467,0.295029,0.00292633,0.974163 beta-lactamase_0_T187E,beta-lactamase_0_187,TEM-1,beta-lactamase_0,P62593,0.974165,NO,187,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.401,-3.52,2.119,,0.007,H,A,0.22,-1.19,3.259,,67.48,PPH,-1.69633,0.0500837,0.00491782,0.974165 beta-lactamase_156_N130D,beta-lactamase_156_130,TEM-1,beta-lactamase_156,P62593,0.97417,NO,130,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-0.798,-3.019,2.221,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.111618,0.000683376,0.97417 beta-lactamase_F13W,beta-lactamase_13,TEM-1,beta-lactamase,P62593,0.974183,NO,13,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-2.394,-5.065,2.671,,,,,,,4.079,,77.62,OHH,-2.382,0.221079,0.0029078,0.974183 beta-lactamase_I3Q,beta-lactamase_3,TEM-1,beta-lactamase,P62593,0.974183,NO,3,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-2.143,-3.814,1.671,,,,,,,3.946,,93.01,PHP,-2.21633,0.221079,0.00349304,0.974183 beta-lactamase_K32I,beta-lactamase_32,TEM-1,beta-lactamase,P62593,0.974183,NO,32,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.984,-2.835,0.851,5.55842,0.563,H,A,1.82,0.34,1.754,,73.08,HBA,-2.04233,0.221079,0.00401283,0.974183 beta-lactamase_L196D,beta-lactamase_196,TEM-1,beta-lactamase,P62593,0.974183,NO,196,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-2.478,-3.862,1.384,,0.518,S,A,0.55,1.35,,,77.62,AHH,-1.839,0.221079,0.00512144,0.974183 beta-lactamase_R271I,beta-lactamase_271,TEM-1,beta-lactamase,P62593,0.974183,NO,271,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.249,-3.756,2.507,5.24516,0.085,H,A,1.67,-0.05,0.474,,63.99,ABP,-1.36633,0.221079,0.00752082,0.974183 beta-lactamase_W163N,beta-lactamase_163,TEM-1,beta-lactamase,P62593,0.974183,NO,163,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-1.843,-2.852,1.009,6.2765,0.467,,B,1.22,-0.5,3.642,,63.99,BHA,-1.269,0.221079,0.00418955,0.974183 beta-lactamase_39_M115E,beta-lactamase_39_115,TEM-1,beta-lactamase_39,P62593,0.974196,NO,115,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.389,-3.76,2.371,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.0495842,0.0034337,0.974196 beta-lactamase_625_A222M,beta-lactamase_625_222,TEM-1,beta-lactamase_625,P62593,0.974205,NO,222,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.103,-4.656,2.553,,0.233,H,A,0.46,-0.25,1.448,,77.62,PHH,-1.63733,0.213352,0.00466094,0.974205 beta-lactamase_625_R81N,beta-lactamase_625_81,TEM-1,beta-lactamase_625,P62593,0.974207,NO,81,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.466,-2.825,1.359,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.213352,0.00499763,0.974207 beta-lactamase_156_F228K,beta-lactamase_156_228,TEM-1,beta-lactamase_156,P62593,0.974208,NO,228,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-2.342,-2.864,0.522,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.111618,0.0046669,0.974208 beta-lactamase_2500_T198Q,beta-lactamase_2500_198,TEM-1,beta-lactamase_2500,P62593,0.974229,NO,198,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.168,-2.734,0.566,,0.489,,B,0.22,-0.13,0.37,,73.78,HPH,-1.98767,0.361275,0.004311,0.974229 beta-lactamase_39_E119F,beta-lactamase_39_119,TEM-1,beta-lactamase_39,P62593,0.974229,NO,119,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.412,-4.398,2.986,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.0495842,0.00386966,0.974229 beta-lactamase_156_G253H,beta-lactamase_156_253,TEM-1,beta-lactamase_156,P62593,0.974234,NO,253,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.111618,0.00786358,0.974234 beta-lactamase_2500_E56A,beta-lactamase_2500_56,TEM-1,beta-lactamase_2500,P62593,0.974234,NO,56,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.043,-2.078,0.035,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.361275,0.00238534,0.974234 Pab1_A158P,Pab1_158,Pab1,Pab1,P04147,0.974247,NO,158,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.154,-3.575,2.421,,,,,,,1.197,,56.33,HHP,-1.40733,0.175299,0.000649733,0.974247 kka2_1:2_A87C,kka2_1:2_87,Kka2,kka2_1:2,P00552,0.974261,NO,87,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.917,-5.153,3.236,,1.039,S,L,0.46,1.57,22.675,22.675,65.53,AHO,-1.822,0.295029,0.00791281,0.974261 kka2_1:1_Q26L,kka2_1:1_26,Kka2,kka2_1:1,P00552,0.974268,NO,26,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.18,-2.769,0.589,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.520039,0.00708962,0.974268 beta-lactamase_0_S233Y,beta-lactamase_0_233,TEM-1,beta-lactamase_0,P62593,0.974285,NO,233,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.886,-4.293,2.407,,0.016,E,B,0.27,-1.01,3.579,,77.62,BPO,-1.17267,0.0500837,0.00311415,0.974285 beta-lactamase_2500_E238T,beta-lactamase_2500_238,TEM-1,beta-lactamase_2500,P62593,0.974301,NO,238,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.361275,0.00743256,0.974301 beta-lactamase_2500_E145R,beta-lactamase_2500_145,TEM-1,beta-lactamase_2500,P62593,0.974303,NO,145,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.357,-2.676,0.319,,0.545,H,A,1.04,0.79,2.124,,77.62,BAH,-2.069,0.361275,0.00553285,0.974303 beta-lactamase_2500_S51E,beta-lactamase_2500_51,TEM-1,beta-lactamase_2500,P62593,0.974304,NO,51,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.526,-3.428,1.902,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.361275,0.00504821,0.974304 beta-lactamase_G216A,beta-lactamase_216,TEM-1,beta-lactamase,P62593,0.974308,NO,216,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.477,-2.596,1.119,4.91694,0.437,I,A,0.23,-0.58,1.718,,74.48,HOO,-1.68067,0.221079,0.00639568,0.974308 beta-lactamase_T267M,beta-lactamase_267,TEM-1,beta-lactamase,P62593,0.974308,NO,267,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.308,-4.762,2.454,5.28263,0.54,,B,0.69,-0.14,0.374,,73.78,HPH,-1.9,0.221079,0.0102128,0.974308 Pab1_L190H,Pab1_190,Pab1,Pab1,P04147,0.974327,NO,190,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.325,-4.68,3.355,,0.489,E,B,,2.59,,,,HHH,-1.31033,0.175299,0.00132347,0.974327 beta-lactamase_156_M153Y,beta-lactamase_156_153,TEM-1,beta-lactamase_156,P62593,0.974335,NO,153,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-3.193,-4.187,0.994,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.111618,0.00509109,0.974335 beta-lactamase_2500_G253N,beta-lactamase_2500_253,TEM-1,beta-lactamase_2500,P62593,0.974343,NO,253,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.361275,0.00786358,0.974343 beta-lactamase_625_R162D,beta-lactamase_625_162,TEM-1,beta-lactamase_625,P62593,0.974345,NO,162,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.016,-3.754,2.738,,0.124,S,B,1.2,-0.37,1.445,,64.69,ABH,-1.25,0.213352,0.000561334,0.974345 beta-lactamase_0_R189Q,beta-lactamase_0_189,TEM-1,beta-lactamase_0,P62593,0.974347,NO,189,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.844,-2.262,0.418,,0.278,H,A,1.2,1.01,12.11,12.11,72.73,HBB,-1.668,0.0500837,0.0050699,0.974347 beta-lactamase_2500_E279R,beta-lactamase_2500_279,TEM-1,beta-lactamase_2500,P62593,0.974358,NO,279,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.361275,0.0192826,0.974358 E1_Ubiquitin_A46H,E1_Ubiquitin_46,Uba1,E1_Ubiquitin,P0CG63,0.974359,NO,46,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.367,-4.621,3.254,,0.398,T,L,,-0.8,,,,HHO,-1.17167,0.18783,0.004233,0.974359 E1_Ubiquitin_G47V,E1_Ubiquitin_47,Uba1,E1_Ubiquitin,P0CG63,0.974359,NO,47,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.999,-3.564,2.565,,0.057,T,l,,-1.21,,,,HOB,-1.195,0.18783,0.00142261,0.974359 E1_Ubiquitin_L71N,E1_Ubiquitin_71,Uba1,E1_Ubiquitin,P0CG63,0.974359,NO,71,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.039,-3.94,2.901,,0.591,E,B,,-0.69,,,,BHB,-1.19433,0.18783,0.00148349,0.974359 E1_Ubiquitin_Q40R,E1_Ubiquitin_40,Uba1,E1_Ubiquitin,P0CG63,0.974359,NO,40,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-1.48,-3.253,1.773,,0.387,G,A,,0.03,,,,OPP,-1.365,0.18783,0.0037961,0.974359 E1_Ubiquitin_T68I,E1_Ubiquitin_68,Uba1,E1_Ubiquitin,P0CG63,0.974359,NO,68,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,,,,,,,,,,,,,OPH,-1.039,0.18783,0.00314321,0.974359 beta-lactamase_39_G39L,beta-lactamase_39_39,TEM-1,beta-lactamase_39,P62593,0.974365,NO,39,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.864,-3.751,1.887,,0.701,T,L,0.29,0.47,1.454,,77.62,HOH,-1.53633,0.0495842,0.00487611,0.974365 beta-lactamase_0_T264G,beta-lactamase_0_264,TEM-1,beta-lactamase_0,P62593,0.97439,NO,264,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.0500837,0.0119399,0.97439 kka2_1:8_R143F,kka2_1:8_143,Kka2,kka2_1:8,P00552,0.974395,NO,143,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.525,-4.3,1.775,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.100394,0.00662247,0.974395 kka2_1:8_R143F,kka2_1:8_143,Kka2,kka2_1:8,P00552,0.974395,NO,143,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.525,-4.3,1.775,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.100394,0.00662247,0.974395 beta-lactamase_2500_S283L,beta-lactamase_2500_283,TEM-1,beta-lactamase_2500,P62593,0.974398,NO,283,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.361275,0.0429138,0.974398 beta-lactamase_2500_P60V,beta-lactamase_2500_60,TEM-1,beta-lactamase_2500,P62593,0.974402,NO,60,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-2.469,-3.507,1.038,,0.256,T,A,0.52,-0.56,1.581,,77.62,BOA,-1.97633,0.361275,0.00521318,0.974402 beta-lactamase_39_H94R,beta-lactamase_39_94,TEM-1,beta-lactamase_39,P62593,0.974405,NO,94,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-2.5,-2.531,0.031,,0.776,,B,0.17,1.24,11.583,11.583,77.62,HBH,-1.872,0.0495842,0.00389226,0.974405 beta-lactamase_2500_G194H,beta-lactamase_2500_194,TEM-1,beta-lactamase_2500,P62593,0.974415,NO,194,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.396,-4.628,3.232,,0.276,S,b,0.29,0.36,3.593,,67.83,POA,-1.832,0.361275,0.00392163,0.974415 beta-lactamase_E62T,beta-lactamase_62,TEM-1,beta-lactamase,P62593,0.97444,NO,62,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.193,-3.522,2.329,5.93066,0.342,S,B,1.52,-0.3,3.139,,73.08,AAB,-1.417,0.221079,0.00264802,0.97444 beta-lactamase_I283M,beta-lactamase_283,TEM-1,beta-lactamase,P62593,0.97444,NO,283,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.638,-3.011,1.373,5.4178,0.165,H,A,1.23,0.04,1.576,,69.23,HHB,-1.735,0.221079,0.0429138,0.97444 beta-lactamase_I54H,beta-lactamase_54,TEM-1,beta-lactamase,P62593,0.97444,NO,54,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-2.838,-3.42,0.582,5.40541,0.669,E,B,0.77,-0.14,3.946,,73.78,BHH,-2.337,0.221079,0.00403589,0.97444 beta-lactamase_39_E102N,beta-lactamase_39_102,TEM-1,beta-lactamase_39,P62593,0.974444,NO,102,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.118,-3.596,1.478,,0.722,S,B,1.04,1.82,3.87,,73.08,HAH,-1.581,0.0495842,0.00486633,0.974444 beta-lactamase_2500_G253E,beta-lactamase_2500_253,TEM-1,beta-lactamase_2500,P62593,0.974446,NO,253,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.361275,0.00786358,0.974446 kka2_1:8_L243G,kka2_1:8_243,Kka2,kka2_1:8,P00552,0.974455,NO,243,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-2.651,-3.604,0.953,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.100394,0.00884927,0.974455 kka2_1:8_L243G,kka2_1:8_243,Kka2,kka2_1:8,P00552,0.974455,NO,243,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-2.651,-3.604,0.953,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.100394,0.00884927,0.974455 beta-lactamase_2500_D113V,beta-lactamase_2500_113,TEM-1,beta-lactamase_2500,P62593,0.974458,NO,113,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.829,-3.01,1.181,,0.665,T,A,0.75,0.91,21.104,21.104,73.08,PAO,-1.703,0.361275,0.00474112,0.974458 beta-lactamase_2500_E102N,beta-lactamase_2500_102,TEM-1,beta-lactamase_2500,P62593,0.974458,NO,102,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.118,-3.596,1.478,,0.722,S,B,1.04,1.82,1.336,,73.08,HAH,-1.581,0.361275,0.00486633,0.974458 beta-lactamase_E87L,beta-lactamase_87,TEM-1,beta-lactamase,P62593,0.974463,NO,87,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.421,-2.529,1.108,5.41929,0.048,,B,0.52,0.92,1.754,,64.69,PAP,-1.969,0.221079,0.00337888,0.974463 beta-lactamase_156_V101R,beta-lactamase_156_101,TEM-1,beta-lactamase_156,P62593,0.974464,NO,101,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.295,-4.134,2.839,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.111618,0.00374492,0.974464 beta-lactamase_39_S266M,beta-lactamase_39_266,TEM-1,beta-lactamase_39,P62593,0.974476,NO,266,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.0495842,0.0140785,0.974476 beta-lactamase_39_N134C,beta-lactamase_39_134,TEM-1,beta-lactamase_39,P62593,0.974477,NO,134,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-0.879,-5.113,4.234,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.0495842,0.000644786,0.974477 beta-lactamase_39_R239T,beta-lactamase_39_239,TEM-1,beta-lactamase_39,P62593,0.974489,NO,239,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.0495842,0.00213852,0.974489 beta-lactamase_39_Y103Q,beta-lactamase_39_103,TEM-1,beta-lactamase_39,P62593,0.974489,NO,103,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-1.33,-2.924,1.594,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.0495842,0.00443048,0.974489 beta-lactamase_625_Q276K,beta-lactamase_625_276,TEM-1,beta-lactamase_625,P62593,0.9745,NO,276,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.213352,0.0191712,0.9745 beta-lactamase_39_D83P,beta-lactamase_39_83,TEM-1,beta-lactamase_39,P62593,0.974513,NO,83,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.066,-3.748,2.682,,0.354,H,A,0.75,0.22,0.752,,48.95,HAH,-1.34733,0.0495842,0.00205968,0.974513 beta-lactamase_625_D33G,beta-lactamase_625_33,TEM-1,beta-lactamase_625,P62593,0.974513,NO,33,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.321,-3.465,1.144,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.213352,0.00435556,0.974513 beta-lactamase_625_N98E,beta-lactamase_625_98,TEM-1,beta-lactamase_625,P62593,0.974525,NO,98,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-2.973,-2.445,-0.528,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.213352,0.00505389,0.974525 beta-lactamase_A200V,beta-lactamase_200,TEM-1,beta-lactamase,P62593,0.974539,NO,200,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.878,-2.943,1.065,5.19406,0.757,H,A,0.47,-0.19,0.436,,77.62,HHP,-2.001,0.221079,0.0060056,0.974539 beta-lactamase_625_R273I,beta-lactamase_625_273,TEM-1,beta-lactamase_625,P62593,0.974542,NO,273,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.314,-4.08,1.766,,0.564,H,A,1.2,1.57,1.455,,73.78,ABP,-1.841,0.213352,0.0077952,0.974542 beta-lactamase_L160S,beta-lactamase_160,TEM-1,beta-lactamase,P62593,0.974544,NO,160,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.977,-3.653,2.676,5.32068,0.022,,B,1.75,-0.6,0.895,,44.41,BHA,-0.936,0.221079,0.00193775,0.974544 Pab1_T159P,Pab1_159,Pab1,Pab1,P04147,0.974545,NO,159,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.445,-3.701,2.256,,,,,,,2.531,,79.03,HPA,-1.19467,0.175299,0.00133849,0.974545 beta-lactamase_156_A268V,beta-lactamase_156_268,TEM-1,beta-lactamase_156,P62593,0.974555,NO,268,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.111618,0.0102525,0.974555 beta-lactamase_Y95I,beta-lactamase_95,TEM-1,beta-lactamase,P62593,0.974579,NO,95,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-1.715,-1.963,0.248,5.67068,0.122,,b,0.96,-0.37,2.341,,77.62,BHP,-2.16167,0.221079,0.00479449,0.974579 beta-lactamase_39_D207A,beta-lactamase_39_207,TEM-1,beta-lactamase_39,P62593,0.974585,NO,207,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.064,-2.585,0.521,,0.409,H,A,0.75,0.12,14.511,14.511,77.62,HAH,-1.77033,0.0495842,0.00592942,0.974585 beta-lactamase_0_G194P,beta-lactamase_0_194,TEM-1,beta-lactamase_0,P62593,0.974592,NO,194,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.396,-3.912,2.516,,0.276,S,b,0.29,0.36,3.017,,67.83,POA,-1.832,0.0500837,0.00392163,0.974592 beta-lactamase_625_L111C,beta-lactamase_625_111,TEM-1,beta-lactamase_625,P62593,0.9746,NO,111,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.76,-4.796,3.036,,0.328,T,A,0.55,0.93,2.26,,64.34,BHP,-1.884,0.213352,0.00480671,0.9746 beta-lactamase_39_E169R,beta-lactamase_39_169,TEM-1,beta-lactamase_39,P62593,0.974609,NO,169,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.23,-3.638,2.408,,0.337,,A,1.04,1,15.633,15.633,73.08,PAH,-1.16533,0.0495842,0.00400994,0.974609 beta-lactamase_625_E62R,beta-lactamase_625_62,TEM-1,beta-lactamase_625,P62593,0.974615,NO,62,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.193,-3.663,2.47,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.213352,0.00264802,0.974615 PSD95pdz3_V365D,PSD95pdz3_365,PSD95pdz3,PSD95pdz3,P31016,0.974616,NO,365,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.592,-3.6,2.008,5.03791,,,,,18.9657,2.364,,81.35,OHA,-1.288,0.0758425,0.000649764,0.974616 beta-lactamase_39_E62G,beta-lactamase_39_62,TEM-1,beta-lactamase_39,P62593,0.974619,NO,62,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.193,-2.548,1.355,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.0495842,0.00264802,0.974619 beta-lactamase_625_T147K,beta-lactamase_625_147,TEM-1,beta-lactamase_625,P62593,0.974636,NO,147,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.149,-3.536,2.387,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.213352,0.00226017,0.974636 beta-lactamase_0_Q37W,beta-lactamase_0_37,TEM-1,beta-lactamase_0,P62593,0.974647,NO,37,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.134,-3.439,1.305,,0.613,H,A,0.64,1.98,4.001,,73.08,APH,-2.06967,0.0500837,0.00425833,0.974647 beta-lactamase_39_G154H,beta-lactamase_39_154,TEM-1,beta-lactamase_39,P62593,0.974647,NO,154,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.823,-4.704,3.881,,0.54,T,l,0.29,-0.56,1.151,,64.69,HOA,-1.635,0.0495842,0.00180205,0.974647 beta-lactamase_39_D48K,beta-lactamase_39_48,TEM-1,beta-lactamase_39,P62593,0.974664,NO,48,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.101,-3.448,2.347,,0.189,E,B,0.75,0.21,0.735,,50.35,HAH,-1.62467,0.0495842,0.0027273,0.974664 beta-lactamase_2500_S256H,beta-lactamase_2500_256,TEM-1,beta-lactamase_2500,P62593,0.974671,NO,256,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.361275,0.00710634,0.974671 beta-lactamase_39_R159C,beta-lactamase_39_159,TEM-1,beta-lactamase_39,P62593,0.974677,NO,159,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-0.94,-5.113,4.173,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.0495842,0.00108472,0.974677 beta-lactamase_625_F228Q,beta-lactamase_625_228,TEM-1,beta-lactamase_625,P62593,0.974679,NO,228,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-2.342,-2.674,0.332,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.213352,0.0046669,0.974679 beta-lactamase_625_E279C,beta-lactamase_625_279,TEM-1,beta-lactamase_625,P62593,0.974697,NO,279,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.213352,0.0192826,0.974697 beta-lactamase_2500_Q37D,beta-lactamase_2500_37,TEM-1,beta-lactamase_2500,P62593,0.974707,NO,37,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.134,-2.904,0.77,,0.613,H,A,0.64,1.98,1.318,,73.08,APH,-2.06967,0.361275,0.00425833,0.974707 beta-lactamase_39_S96Y,beta-lactamase_39_96,TEM-1,beta-lactamase_39,P62593,0.974723,NO,96,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.27,-4.345,2.075,,0.368,,b,0.27,0.39,2.516,,73.78,HPP,-2.019,0.0495842,0.00551835,0.974723 beta-lactamase_39_R275H,beta-lactamase_39_275,TEM-1,beta-lactamase_39,P62593,0.974725,NO,275,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.0495842,0.0141984,0.974725 beta-lactamase_H94H,beta-lactamase_94,TEM-1,beta-lactamase,P62593,0.974726,NO,94,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-2.5,-2.5,,6.1507,0.776,,B,0.63,1.24,1.176,,77.62,HBH,-1.872,0.221079,0.00389226,0.974726 beta-lactamase_0_L49N,beta-lactamase_0_49,TEM-1,beta-lactamase_0,P62593,0.974737,NO,49,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.897,-3.842,1.945,,0.131,T,A,0.55,0.04,13.838,13.838,64.69,AHP,-1.99233,0.0500837,0.00401477,0.974737 beta-lactamase_156_L137Y,beta-lactamase_156_137,TEM-1,beta-lactamase_156,P62593,0.974739,NO,137,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.03,-4.002,2.972,,,H,A,0.55,-0.38,0.674,,42.31,HHP,-1.58933,0.111618,0.00278599,0.974739 beta-lactamase_2500_Q204H,beta-lactamase_2500_204,TEM-1,beta-lactamase_2500,P62593,0.97474,NO,204,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-1.382,-3.09,1.708,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.361275,0.00364106,0.97474 beta-lactamase_39_E56A,beta-lactamase_39_56,TEM-1,beta-lactamase_39,P62593,0.974765,NO,56,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.043,-2.078,0.035,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.0495842,0.00238534,0.974765 beta-lactamase_2500_T187D,beta-lactamase_2500_187,TEM-1,beta-lactamase_2500,P62593,0.974771,NO,187,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.401,-2.769,1.368,,0.007,H,A,0.22,-1.19,3.91,,67.48,PPH,-1.69633,0.361275,0.00491782,0.974771 Pab1_Y143K,Pab1_143,Pab1,Pab1,P04147,0.974777,NO,143,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-1.961,-3.515,1.554,,0.409,H,A,,0.3,,,,HHA,-1.39633,0.175299,0.00160364,0.974777 PSD95pdz3_T387P,PSD95pdz3_387,PSD95pdz3,PSD95pdz3,P31016,0.974779,NO,387,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.391,-3.336,1.945,5.20757,,,,,18.8043,,,,HPH,-1.49533,0.0758425,0.000167911,0.974779 beta-lactamase_156_P172D,beta-lactamase_156_172,TEM-1,beta-lactamase_156,P62593,0.974781,NO,172,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.998,-3.578,2.58,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.111618,0.00312594,0.974781 beta-lactamase_39_I229G,beta-lactamase_39_229,TEM-1,beta-lactamase_39,P62593,0.974781,NO,229,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.267,-3.782,2.515,,0.083,E,B,0.48,-0.76,1.114,,50,HHH,-1.58767,0.0495842,0.00477249,0.974781 gb1_A249S,gb1_249,gb1,gb1,P06654,0.974793,NO,249,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.739,-3.034,1.295,,,,,,,0.252,,44.87,AHH,-1.67367,0.177985,0.00333585,0.974793 beta-lactamase_0_Q276T,beta-lactamase_0_276,TEM-1,beta-lactamase_0,P62593,0.974809,NO,276,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.0500837,0.0191712,0.974809 beta-lactamase_0_L73D,beta-lactamase_0_73,TEM-1,beta-lactamase_0,P62593,0.974816,NO,73,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.507,-4.091,2.584,,,H,A,0.55,-0.64,0.877,,67.83,HHH,-1.487,0.0500837,0.00488983,0.974816 beta-lactamase_0_T139Q,beta-lactamase_0_139,TEM-1,beta-lactamase_0,P62593,0.974818,NO,139,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.901,-2.8,0.899,,0.216,H,A,0.22,0.39,0.421,,77.62,PPH,-2.04667,0.0500837,0.00441837,0.974818 beta-lactamase_K144P,beta-lactamase_144,TEM-1,beta-lactamase,P62593,0.974828,NO,144,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-2.388,-2.633,0.245,6.02507,0.863,H,A,2.81,1.27,0.515,,77.62,OBA,-1.904,0.221079,0.00481141,0.974828 beta-lactamase_625_L120A,beta-lactamase_625_120,TEM-1,beta-lactamase_625,P62593,0.974837,NO,120,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.044,-3.203,2.159,,,H,A,0.55,-1.13,7.813,,64.69,AHO,-1.13633,0.213352,0.00143563,0.974837 Pab1_A178E,Pab1_178,Pab1,Pab1,P04147,0.974845,NO,178,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.579,-3.199,1.62,,0.019,H,A,0.64,0.64,2.7,,81.63,OHH,-1.61067,0.175299,0.00160192,0.974845 beta-lactamase_0_I245A,beta-lactamase_0_245,TEM-1,beta-lactamase_0,P62593,0.974847,NO,245,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.068,-3.611,2.543,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.0500837,0.00391032,0.974847 beta-lactamase_156_R220L,beta-lactamase_156_220,TEM-1,beta-lactamase_156,P62593,0.974855,NO,220,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-0.942,-3.356,2.414,,0.295,I,A,1.2,-0.76,2.164,,74.48,HBP,-1.33633,0.111618,0.00232421,0.974855 beta-lactamase_625_D33E,beta-lactamase_625_33,TEM-1,beta-lactamase_625,P62593,0.974862,NO,33,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.321,-2.159,-0.162,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.213352,0.00435556,0.974862 Pab1_D160Q,Pab1_160,Pab1,Pab1,P04147,0.97487,NO,160,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.985,-3.491,2.506,,0.396,B,B,,1.12,,,,PAA,-1.30133,0.175299,0.000311977,0.97487 beta-lactamase_39_A182Y,beta-lactamase_39_182,TEM-1,beta-lactamase_39,P62593,0.974881,NO,182,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.777,-4.299,2.522,,0.136,H,A,0.46,-0.66,2.598,,93.01,OHH,-1.27367,0.0495842,0.00559099,0.974881 beta-lactamase_A124S,beta-lactamase_124,TEM-1,beta-lactamase,P62593,0.974881,NO,124,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.181,-3.066,1.885,4.58507,,H,A,0.58,-0.9,2.273,,64.34,HHH,-1.152,0.221079,0.00481399,0.974881 beta-lactamase_2500_Y95I,beta-lactamase_2500_95,TEM-1,beta-lactamase_2500,P62593,0.974888,NO,95,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-1.715,-1.963,0.248,,0.122,,b,0.21,-0.37,2.914,,77.62,BHP,-2.16167,0.361275,0.00479449,0.974888 Pab1_E181Y,Pab1_181,Pab1,Pab1,P04147,0.974892,NO,181,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.767,-4.16,2.393,,,,,,,1.395,,73.83,BAH,-1.575,0.175299,0.00107557,0.974892 beta-lactamase_39_P217F,beta-lactamase_39_217,TEM-1,beta-lactamase_39,P62593,0.974897,NO,217,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-2.062,-4.432,2.37,,0.496,I,A,0.52,-0.33,21.172,21.172,74.48,OOH,-1.64333,0.0495842,0.00463211,0.974897 beta-lactamase_156_G240N,beta-lactamase_156_240,TEM-1,beta-lactamase_156,P62593,0.974911,NO,240,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.111618,0.00591201,0.974911 beta-lactamase_0_H24L,beta-lactamase_0_24,TEM-1,beta-lactamase_0,P62593,0.974925,NO,24,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-2.481,-3.404,0.923,,,,,,,2.708,,93.01,OBO,-2.0035,0.0500837,0.00238894,0.974925 beta-lactamase_2500_A222S,beta-lactamase_2500_222,TEM-1,beta-lactamase_2500,P62593,0.974941,NO,222,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.103,-2.253,0.15,,0.233,H,A,0.46,-0.25,0.379,,77.62,PHH,-1.63733,0.361275,0.00466094,0.974941 beta-lactamase_625_A268K,beta-lactamase_625_268,TEM-1,beta-lactamase_625,P62593,0.974941,NO,268,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.213352,0.0102525,0.974941 beta-lactamase_625_R159L,beta-lactamase_625_159,TEM-1,beta-lactamase_625,P62593,0.974944,NO,159,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-0.94,-3.407,2.467,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.213352,0.00108472,0.974944 beta-lactamase_2500_G226E,beta-lactamase_2500_226,TEM-1,beta-lactamase_2500,P62593,0.974962,NO,226,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.461,-2.776,1.315,,0.701,T,l,0.29,-0.25,5.086,,74.48,HOH,-1.42933,0.361275,0.00665294,0.974962 beta-lactamase_39_L100Y,beta-lactamase_39_100,TEM-1,beta-lactamase_39,P62593,0.974963,NO,100,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.218,-2.879,1.661,,0.343,,B,0.55,0.13,8.311,,63.29,AHH,-1.23467,0.0495842,0.00413885,0.974963 beta-lactamase_2500_D113R,beta-lactamase_2500_113,TEM-1,beta-lactamase_2500,P62593,0.974979,NO,113,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.829,-2.854,1.025,,0.665,T,A,0.75,0.91,21.104,21.104,73.08,PAO,-1.703,0.361275,0.00474112,0.974979 beta-lactamase_Q86G,beta-lactamase_86,TEM-1,beta-lactamase,P62593,0.974979,NO,86,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.4,-2.887,0.487,5.39897,0.696,S,A,0.12,2.38,2.105,,77.62,OPA,-1.61067,0.221079,0.00450027,0.974979 beta-lactamase_2500_M127T,beta-lactamase_2500_127,TEM-1,beta-lactamase_2500,P62593,0.974983,NO,127,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-2.251,-2.593,0.342,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.361275,0.00437927,0.974983 beta-lactamase_156_P255C,beta-lactamase_156_255,TEM-1,beta-lactamase_156,P62593,0.974985,NO,255,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.111618,0.00499612,0.974985 beta-lactamase_39_A222S,beta-lactamase_39_222,TEM-1,beta-lactamase_39,P62593,0.974999,NO,222,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.103,-2.253,0.15,,0.233,H,A,0.46,-0.25,1.448,,77.62,PHH,-1.63733,0.0495842,0.00466094,0.974999 kka2_1:8_R44D,kka2_1:8_44,Kka2,kka2_1:8,P00552,0.975023,NO,44,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.062,-3.066,1.004,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.100394,0.00745043,0.975023 kka2_1:8_R44D,kka2_1:8_44,Kka2,kka2_1:8,P00552,0.975023,NO,44,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.062,-3.066,1.004,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.100394,0.00745043,0.975023 beta-lactamase_156_C121S,beta-lactamase_156_121,TEM-1,beta-lactamase_156,P62593,0.975029,NO,121,C,S,CS,Special,Polar,5.07,5.68,0.61,112,121,105,-16,108.5,89,-19.5,-0.953,-3.411,2.458,,,H,A,0.46,-0.81,1.136,,63.29,HOP,-1.46767,0.111618,0.000744322,0.975029 kka2_1:4_R202D,kka2_1:4_202,Kka2,kka2_1:4,P00552,0.975035,NO,202,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.761,-2.83,1.069,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.168804,0.00696498,0.975035 beta-lactamase_625_T116I,beta-lactamase_625_116,TEM-1,beta-lactamase_625,P62593,0.975037,NO,116,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.28,-3.822,2.542,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.213352,0.00336175,0.975037 beta-lactamase_2500_I171M,beta-lactamase_2500_171,TEM-1,beta-lactamase_2500,P62593,0.975044,NO,171,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-2.431,-4.454,2.023,,0.361,,B,0.48,0.53,1.66,,77.62,HHO,-1.55533,0.361275,0.00623355,0.975044 beta-lactamase_D113H,beta-lactamase_113,TEM-1,beta-lactamase,P62593,0.975045,NO,113,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.829,-4.704,2.875,6.04499,0.665,T,A,0.23,0.91,21.104,21.104,73.08,PAO,-1.703,0.221079,0.00474112,0.975045 beta-lactamase_G39Q,beta-lactamase_39,TEM-1,beta-lactamase,P62593,0.975045,NO,39,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.864,-2.885,1.021,5.35574,0.701,T,L,0.23,0.47,29.926,29.926,77.62,HOH,-1.53633,0.221079,0.00487611,0.975045 beta-lactamase_H285C,beta-lactamase_285,TEM-1,beta-lactamase,P62593,0.975045,NO,285,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-1.845,-5.065,3.22,5.64289,0.312,T,a,0.35,0.64,1.401,,72.73,BBH,-1.64567,0.221079,0.101555,0.975045 beta-lactamase_M180W,beta-lactamase_180,TEM-1,beta-lactamase,P62593,0.975045,NO,180,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-2.795,-5.124,2.329,4.96809,0.242,,B,1.07,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.221079,0.00552048,0.975045 beta-lactamase_R162N,beta-lactamase_162,TEM-1,beta-lactamase,P62593,0.975045,NO,162,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.016,-3.588,2.572,5.34456,0.124,S,B,0.68,-0.37,31.656,31.656,64.69,ABH,-1.25,0.221079,0.000561334,0.975045 beta-lactamase_2500_E279A,beta-lactamase_2500_279,TEM-1,beta-lactamase_2500,P62593,0.975046,NO,279,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.361275,0.0192826,0.975046 kka2_1:4_R145G,kka2_1:4_145,Kka2,kka2_1:4,P00552,0.975054,NO,145,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.804,-2.912,1.108,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.168804,0.00846663,0.975054 Pab1_E161L,Pab1_161,Pab1,Pab1,P04147,0.975056,NO,161,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.474,-3.509,2.035,,0.663,T,a,,1.34,,,,AAP,-1.59067,0.175299,0.00276141,0.975056 Pab1_S165P,Pab1_165,Pab1,Pab1,P04147,0.975056,NO,165,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.146,-3.472,2.326,,0.12,,a,,0.11,,,,BPB,-1.56867,0.175299,0.000307838,0.975056 beta-lactamase_39_L205Y,beta-lactamase_39_205,TEM-1,beta-lactamase_39,P62593,0.975067,NO,205,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.922,-3.727,2.805,,,H,A,0.55,-0.46,0.846,,42.31,PHH,-1.57767,0.0495842,0.00255802,0.975067 beta-lactamase_156_V101K,beta-lactamase_156_101,TEM-1,beta-lactamase_156,P62593,0.975069,NO,101,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.295,-3.742,2.447,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.111618,0.00374492,0.975069 beta-lactamase_39_K144Q,beta-lactamase_39_144,TEM-1,beta-lactamase_39,P62593,0.975079,NO,144,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-2.388,-2.378,-0.01,,0.863,H,A,2.34,1.27,14.556,14.556,77.62,OBA,-1.904,0.0495842,0.00481141,0.975079 beta-lactamase_39_E169V,beta-lactamase_39_169,TEM-1,beta-lactamase_39,P62593,0.975081,NO,169,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.23,-3.538,2.308,,0.337,,A,1.04,1,15.633,15.633,73.08,PAH,-1.16533,0.0495842,0.00400994,0.975081 beta-lactamase_39_L111T,beta-lactamase_39_111,TEM-1,beta-lactamase_39,P62593,0.975082,NO,111,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.76,-2.765,1.005,,0.328,T,A,0.55,0.93,4.334,,64.34,BHP,-1.884,0.0495842,0.00480671,0.975082 beta-lactamase_2500_E169L,beta-lactamase_2500_169,TEM-1,beta-lactamase_2500,P62593,0.975095,NO,169,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.23,-3.533,2.303,,0.337,,A,1.04,1,1.806,,73.08,PAH,-1.16533,0.361275,0.00400994,0.975095 beta-lactamase_156_D33W,beta-lactamase_156_33,TEM-1,beta-lactamase_156,P62593,0.975118,NO,33,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.321,-5.495,3.174,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.111618,0.00435556,0.975118 beta-lactamase_0_E56A,beta-lactamase_0_56,TEM-1,beta-lactamase_0,P62593,0.975119,NO,56,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.043,-2.078,0.035,,0.198,E,B,1.04,0.31,1.491,,72.73,HAP,-1.94033,0.0500837,0.00238534,0.975119 beta-lactamase_156_E272N,beta-lactamase_156_272,TEM-1,beta-lactamase_156,P62593,0.975122,NO,272,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.127,-2.497,1.37,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.111618,0.00545371,0.975122 beta-lactamase_2500_A225E,beta-lactamase_2500_225,TEM-1,beta-lactamase_2500,P62593,0.975122,NO,225,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.845,-2.246,0.401,,1,T,B,0.46,-0.38,0.551,,74.48,OHO,-1.39967,0.361275,0.00465057,0.975122 beta-lactamase_156_D161S,beta-lactamase_156_161,TEM-1,beta-lactamase_156,P62593,0.975123,NO,161,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.891,-2.488,1.597,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.111618,0.000897697,0.975123 beta-lactamase_D269C,beta-lactamase_269,TEM-1,beta-lactamase,P62593,0.975131,NO,269,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.156,-5.062,2.906,5.47645,0.646,H,A,0.23,0.4,21.796,21.796,77.62,HAA,-1.96733,0.221079,0.00950944,0.975131 beta-lactamase_39_N173F,beta-lactamase_39_173,TEM-1,beta-lactamase_39,P62593,0.975132,NO,173,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-2.663,-4.355,1.692,,1.044,T,l,0.61,1.25,1.426,,77.62,OPA,-1.46633,0.0495842,0.0033769,0.975132 beta-lactamase_156_F70H,beta-lactamase_156_70,TEM-1,beta-lactamase_156,P62593,0.975134,NO,70,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.169,-4.494,3.325,,,H,A,0.58,-1.34,1.918,,63.99,PHB,-0.980667,0.111618,0.00193499,0.975134 beta-lactamase_156_R275N,beta-lactamase_156_275,TEM-1,beta-lactamase_156,P62593,0.975143,NO,275,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.111618,0.0141984,0.975143 beta-lactamase_39_E102H,beta-lactamase_39_102,TEM-1,beta-lactamase_39,P62593,0.975146,NO,102,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.118,-3.309,1.191,,0.722,S,B,1.04,1.82,3.87,,73.08,HAH,-1.581,0.0495842,0.00486633,0.975146 kka2_1:8_Q136H,kka2_1:8_136,Kka2,kka2_1:8,P00552,0.975147,NO,136,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-3.021,-3.255,0.234,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.100394,0.00624149,0.975147 kka2_1:8_Q136H,kka2_1:8_136,Kka2,kka2_1:8,P00552,0.975147,NO,136,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-3.021,-3.255,0.234,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.100394,0.00624149,0.975147 kka2_1:8_V113T,kka2_1:8_113,Kka2,kka2_1:8,P00552,0.975147,NO,113,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.233,-3.45,2.217,,0.008,H,A,1.48,-1.17,1.254,,52.27,BHP,-2.08367,0.100394,0.00650191,0.975147 kka2_1:8_V113T,kka2_1:8_113,Kka2,kka2_1:8,P00552,0.975147,NO,113,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.233,-3.45,2.217,,0.008,H,A,1.48,-1.17,1.254,,52.27,BHP,-2.08367,0.100394,0.00650191,0.975147 beta-lactamase_F13Y,beta-lactamase_13,TEM-1,beta-lactamase,P62593,0.97516,NO,13,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-2.394,-3.818,1.424,,,,,,,4.079,,77.62,OHH,-2.382,0.221079,0.0029078,0.97516 beta-lactamase_156_Q203T,beta-lactamase_156_203,TEM-1,beta-lactamase_156,P62593,0.975161,NO,203,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.168,-2.523,0.355,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.111618,0.00631514,0.975161 beta-lactamase_0_A200V,beta-lactamase_0_200,TEM-1,beta-lactamase_0,P62593,0.975162,NO,200,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.878,-2.943,1.065,,0.757,H,A,0.46,-0.19,16.368,16.368,77.62,HHP,-2.001,0.0500837,0.0060056,0.975162 beta-lactamase_0_R257P,beta-lactamase_0_257,TEM-1,beta-lactamase_0,P62593,0.975174,NO,257,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.0500837,0.00756629,0.975174 beta-lactamase_625_P172D,beta-lactamase_625_172,TEM-1,beta-lactamase_625,P62593,0.975188,NO,172,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.998,-3.578,2.58,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.213352,0.00312594,0.975188 beta-lactamase_2500_L205M,beta-lactamase_2500_205,TEM-1,beta-lactamase_2500,P62593,0.975191,NO,205,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.922,-3.889,2.967,,,H,A,0.55,-0.46,0.831,,42.31,PHH,-1.57767,0.361275,0.00255802,0.975191 beta-lactamase_2500_K144L,beta-lactamase_2500_144,TEM-1,beta-lactamase_2500,P62593,0.975209,NO,144,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-2.388,-3.577,1.189,,0.863,H,A,2.34,1.27,0.515,,77.62,OBA,-1.904,0.361275,0.00481141,0.975209 beta-lactamase_39_P181C,beta-lactamase_39_181,TEM-1,beta-lactamase_39,P62593,0.975217,NO,181,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.813,-5.009,4.196,,,H,A,0.52,-1.14,1.946,,61.54,HOH,-1.795,0.0495842,0.000703122,0.975217 beta-lactamase_A200I,beta-lactamase_200,TEM-1,beta-lactamase,P62593,0.97522,NO,200,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.878,-3.937,2.059,5.19406,0.757,H,A,0.47,-0.19,0.436,,77.62,HHP,-2.001,0.221079,0.0060056,0.97522 beta-lactamase_L73L,beta-lactamase_73,TEM-1,beta-lactamase,P62593,0.97522,NO,73,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.507,-1.507,,5.84139,,H,A,1.75,-0.64,2.09,,67.83,HHH,-1.487,0.221079,0.00488983,0.97522 beta-lactamase_39_E56V,beta-lactamase_39_56,TEM-1,beta-lactamase_39,P62593,0.975228,NO,56,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.043,-3.397,1.354,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.0495842,0.00238534,0.975228 beta-lactamase_H285R,beta-lactamase_285,TEM-1,beta-lactamase,P62593,0.975236,NO,285,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-1.845,-3.569,1.724,5.64289,0.312,T,a,0.35,0.64,1.401,,72.73,BBH,-1.64567,0.221079,0.101555,0.975236 beta-lactamase_Y44L,beta-lactamase_44,TEM-1,beta-lactamase,P62593,0.975236,NO,44,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-2.547,-2.196,-0.351,5.6273,,E,B,2.55,-0.45,2.683,,73.78,OHH,-1.86267,0.221079,0.00426364,0.975236 beta-lactamase_156_D113A,beta-lactamase_156_113,TEM-1,beta-lactamase_156,P62593,0.975245,NO,113,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.829,-2.412,0.583,,0.665,T,A,0.75,0.91,2.973,,73.08,PAO,-1.703,0.111618,0.00474112,0.975245 beta-lactamase_0_S57L,beta-lactamase_0_57,TEM-1,beta-lactamase_0,P62593,0.97525,NO,57,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.918,-2.848,0.93,,0.352,E,B,0.27,-0.18,1.454,,72.73,APH,-2.29167,0.0500837,0.00492804,0.97525 beta-lactamase_39_Q86P,beta-lactamase_39_86,TEM-1,beta-lactamase_39,P62593,0.975251,NO,86,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.4,-3.985,1.585,,0.696,S,A,0.64,2.38,27.704,27.704,77.62,OPA,-1.61067,0.0495842,0.00450027,0.975251 Pab1_E174D,Pab1_174,Pab1,Pab1,P04147,0.975267,NO,174,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.422,-2.152,0.73,,0.578,S,A,,0.38,,,,HAA,-1.65133,0.175299,0.00077863,0.975267 beta-lactamase_39_A222D,beta-lactamase_39_222,TEM-1,beta-lactamase_39,P62593,0.975273,NO,222,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.103,-3.723,1.62,,0.233,H,A,0.46,-0.25,1.448,,77.62,PHH,-1.63733,0.0495842,0.00466094,0.975273 beta-lactamase_E108D,beta-lactamase_108,TEM-1,beta-lactamase,P62593,0.97528,NO,108,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.46,-2.67,1.21,5.52079,0.572,G,A,0.52,1.87,1.973,,72.73,PAB,-1.437,0.221079,0.00413372,0.97528 beta-lactamase_156_P224Q,beta-lactamase_156_224,TEM-1,beta-lactamase_156,P62593,0.975305,NO,224,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.893,-3.868,2.975,,0.383,,B,0.52,-0.3,0.383,,74.48,HOH,-1.26433,0.111618,0.00189564,0.975305 beta-lactamase_39_P217G,beta-lactamase_39_217,TEM-1,beta-lactamase_39,P62593,0.975315,NO,217,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-2.062,-2.748,0.686,,0.496,I,A,0.52,-0.33,21.172,21.172,74.48,OOH,-1.64333,0.0495842,0.00463211,0.975315 PSD95pdz3_S361E,PSD95pdz3_361,PSD95pdz3,PSD95pdz3,P31016,0.97532,NO,361,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.519,-2.897,1.378,4.8722,,,,,16.4533,,,,HPH,-1.47167,0.0758425,0.00055296,0.97532 beta-lactamase_625_G216D,beta-lactamase_625_216,TEM-1,beta-lactamase_625,P62593,0.975326,NO,216,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.477,-1.722,0.245,,0.437,I,A,0.29,-0.58,1.718,,74.48,HOO,-1.68067,0.213352,0.00639568,0.975326 beta-lactamase_156_G90M,beta-lactamase_156_90,TEM-1,beta-lactamase_156,P62593,0.975332,NO,90,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-2.091,-4.839,2.748,,0.598,T,A,0.29,0.32,0.319,,77.62,HOB,-1.52633,0.111618,0.00490273,0.975332 beta-lactamase_2500_L111Q,beta-lactamase_2500_111,TEM-1,beta-lactamase_2500,P62593,0.975341,NO,111,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.76,-3.108,1.348,,0.328,T,A,0.55,0.93,1.966,,64.34,BHP,-1.884,0.361275,0.00480671,0.975341 beta-lactamase_156_R220E,beta-lactamase_156_220,TEM-1,beta-lactamase_156,P62593,0.975342,NO,220,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-0.942,-3.264,2.322,,0.295,I,A,1.2,-0.76,2.164,,74.48,HBP,-1.33633,0.111618,0.00232421,0.975342 beta-lactamase_156_T126M,beta-lactamase_156_126,TEM-1,beta-lactamase_156,P62593,0.975342,NO,126,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.122,-4.659,3.537,,0.05,H,A,0.22,-0.05,1.14,,44.41,HPH,-1.60467,0.111618,0.00244552,0.975342 beta-lactamase_P25T,beta-lactamase_25,TEM-1,beta-lactamase,P62593,0.975342,NO,25,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.526,-3.483,1.957,5.6134,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.221079,0.00347571,0.975342 beta-lactamase_156_S221C,beta-lactamase_156_221,TEM-1,beta-lactamase_156,P62593,0.975347,NO,221,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.754,-3.097,1.343,,0.624,H,A,0.27,-0.2,17.729,17.729,74.48,BPH,-1.59967,0.111618,0.0046094,0.975347 beta-lactamase_156_P25D,beta-lactamase_156_25,TEM-1,beta-lactamase_156,P62593,0.975353,NO,25,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.526,-2.562,1.036,,0.624,H,A,0.52,0.14,1.079,,73.08,BOA,-2.15367,0.111618,0.00347571,0.975353 kka2_1:8_W236Y,kka2_1:8_236,Kka2,kka2_1:8,P00552,0.975359,NO,236,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-1.363,-2.865,1.502,,0.303,H,A,1.51,-0.76,1.87,,48.48,AHH,-1.81267,0.100394,0.0088796,0.975359 kka2_1:8_W236Y,kka2_1:8_236,Kka2,kka2_1:8,P00552,0.975359,NO,236,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-1.363,-2.865,1.502,,0.303,H,A,1.51,-0.76,1.87,,48.48,AHH,-1.81267,0.100394,0.0088796,0.975359 beta-lactamase_2500_G253D,beta-lactamase_2500_253,TEM-1,beta-lactamase_2500,P62593,0.975373,NO,253,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.361275,0.00786358,0.975373 kka2_1:4_M120I,kka2_1:4_120,Kka2,kka2_1:4,P00552,0.975381,NO,120,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-3.877,-2.912,-0.965,,,H,A,0.55,-0.42,2.259,,92.05,HHB,-2.16733,0.168804,0.00265808,0.975381 beta-lactamase_39_D207F,beta-lactamase_39_207,TEM-1,beta-lactamase_39,P62593,0.975386,NO,207,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.064,-4.437,2.373,,0.409,H,A,0.75,0.12,14.511,14.511,77.62,HAH,-1.77033,0.0495842,0.00592942,0.975386 beta-lactamase_156_R176A,beta-lactamase_156_176,TEM-1,beta-lactamase_156,P62593,0.975392,NO,176,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-0.863,-3.078,2.215,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.111618,0.00105554,0.975392 beta-lactamase_625_L38K,beta-lactamase_625_38,TEM-1,beta-lactamase_625,P62593,0.975396,NO,38,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.343,-3.749,2.406,,0.088,H,A,0.55,0.2,1.986,,64.34,PHO,-1.78033,0.213352,0.00373244,0.975396 kka2_1:4_T146Y,kka2_1:4_146,Kka2,kka2_1:4,P00552,0.975396,NO,146,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.978,-4.381,1.403,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.168804,0.00606474,0.975396 beta-lactamase_39_G90K,beta-lactamase_39_90,TEM-1,beta-lactamase_39,P62593,0.9754,NO,90,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-2.091,-3.514,1.423,,0.598,T,A,0.29,0.32,30.794,30.794,77.62,HOB,-1.52633,0.0495842,0.00490273,0.9754 Pab1_G177W,Pab1_177,Pab1,Pab1,P04147,0.975403,NO,177,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-2.24,-5.29,3.05,,,,,,,,,,AOH,-1.94067,0.175299,0.00170727,0.975403 beta-lactamase_D113Y,beta-lactamase_113,TEM-1,beta-lactamase,P62593,0.975405,NO,113,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.829,-4.441,2.612,6.04499,0.665,T,A,0.23,0.91,21.104,21.104,73.08,PAO,-1.703,0.221079,0.00474112,0.975405 beta-lactamase_D207M,beta-lactamase_207,TEM-1,beta-lactamase,P62593,0.975405,NO,207,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.064,-4.822,2.758,5.40404,0.409,H,A,0.23,0.12,1.975,,77.62,HAH,-1.77033,0.221079,0.00592942,0.975405 beta-lactamase_E102S,beta-lactamase_102,TEM-1,beta-lactamase,P62593,0.975405,NO,102,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.118,-2.129,0.011,6.36157,0.722,S,B,1.5,1.82,1.336,,73.08,HAH,-1.581,0.221079,0.00486633,0.975405 beta-lactamase_L73M,beta-lactamase_73,TEM-1,beta-lactamase,P62593,0.975405,NO,73,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.507,-2.898,1.391,5.84139,,H,A,1.75,-0.64,2.09,,67.83,HHH,-1.487,0.221079,0.00488983,0.975405 beta-lactamase_P12P,beta-lactamase_12,TEM-1,beta-lactamase,P62593,0.975405,NO,12,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-2.016,-2.016,,,,,,,,2.88,,72.73,HOH,-2.05167,0.221079,0.00241653,0.975405 beta-lactamase_Q88M,beta-lactamase_88,TEM-1,beta-lactamase,P62593,0.975405,NO,88,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.086,-3.418,1.332,5.8056,0.807,,B,0.12,2.03,1.84,,77.62,APH,-1.53433,0.221079,0.00504167,0.975405 beta-lactamase_625_R92C,beta-lactamase_625_92,TEM-1,beta-lactamase_625,P62593,0.975406,NO,92,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.718,-5.119,3.401,,0.479,E,B,1.2,1.36,3.069,,65.38,BBH,-1.50367,0.213352,0.00429626,0.975406 beta-lactamase_2500_Q203T,beta-lactamase_2500_203,TEM-1,beta-lactamase_2500,P62593,0.975412,NO,203,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.168,-2.523,0.355,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.361275,0.00631514,0.975412 kka2_1:8_L47N,kka2_1:8_47,Kka2,kka2_1:8,P00552,0.975412,NO,47,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.265,-4.107,2.842,,0.139,E,B,1.59,-0.86,5.086,,63.26,HHH,-1.77933,0.100394,0.00509386,0.975412 kka2_1:8_L47N,kka2_1:8_47,Kka2,kka2_1:8,P00552,0.975412,NO,47,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.265,-4.107,2.842,,0.139,E,B,1.59,-0.86,5.086,,63.26,HHH,-1.77933,0.100394,0.00509386,0.975412 beta-lactamase_2500_R275G,beta-lactamase_2500_275,TEM-1,beta-lactamase_2500,P62593,0.975432,NO,275,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.361275,0.0141984,0.975432 beta-lactamase_156_Q276V,beta-lactamase_156_276,TEM-1,beta-lactamase_156,P62593,0.975439,NO,276,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.111618,0.0191712,0.975439 beta-lactamase_156_N50E,beta-lactamase_156_50,TEM-1,beta-lactamase_156,P62593,0.975443,NO,50,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-2.979,-2.315,-0.664,,0.912,T,A,0.61,1.24,13.295,13.295,77.62,HPP,-2.134,0.111618,0.0047211,0.975443 beta-lactamase_39_S80K,beta-lactamase_39_80,TEM-1,beta-lactamase_39,P62593,0.975444,NO,80,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.029,-2.901,0.872,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.0495842,0.00565569,0.975444 beta-lactamase_2500_N50F,beta-lactamase_2500_50,TEM-1,beta-lactamase_2500,P62593,0.975454,NO,50,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-2.979,-4.333,1.354,,0.912,T,A,0.61,1.24,1.581,,77.62,HPP,-2.134,0.361275,0.0047211,0.975454 beta-lactamase_39_R220C,beta-lactamase_39_220,TEM-1,beta-lactamase_39,P62593,0.975454,NO,220,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-0.942,-5.009,4.067,,0.295,I,A,1.2,-0.76,1.596,,74.48,HBP,-1.33633,0.0495842,0.00232421,0.975454 beta-lactamase_156_Q203A,beta-lactamase_156_203,TEM-1,beta-lactamase_156,P62593,0.975455,NO,203,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.168,-2.117,-0.051,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.111618,0.00631514,0.975455 beta-lactamase_156_A215N,beta-lactamase_156_215,TEM-1,beta-lactamase_156,P62593,0.975461,NO,215,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.503,-3.679,2.176,,,,a,0.46,-0.93,3.583,,74.48,HHO,-1.42633,0.111618,0.00544007,0.975461 beta-lactamase_2500_V157D,beta-lactamase_2500_157,TEM-1,beta-lactamase_2500,P62593,0.975468,NO,157,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.751,-3.908,2.157,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.361275,0.00506849,0.975468 beta-lactamase_2500_N98P,beta-lactamase_2500_98,TEM-1,beta-lactamase_2500,P62593,0.975474,NO,98,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-2.973,-3.946,0.973,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.361275,0.00505389,0.975474 beta-lactamase_625_Y262I,beta-lactamase_625_262,TEM-1,beta-lactamase_625,P62593,0.975485,NO,262,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.213352,0.00853516,0.975485 beta-lactamase_2500_Q204N,beta-lactamase_2500_204,TEM-1,beta-lactamase_2500,P62593,0.975489,NO,204,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-1.382,-3.623,2.241,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.361275,0.00364106,0.975489 beta-lactamase_39_L219H,beta-lactamase_39_219,TEM-1,beta-lactamase_39,P62593,0.975499,NO,219,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.313,-4.957,3.644,,,I,A,0.55,-0.51,19.842,19.842,74.48,HHB,-1.21533,0.0495842,0.00664345,0.975499 kka2_1:8_A191G,kka2_1:8_191,Kka2,kka2_1:8,P00552,0.975501,NO,191,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.831,-3.024,2.193,,,,b,1.04,-0.94,1.306,,50,AHO,-0.868667,0.100394,0.00338807,0.975501 kka2_1:8_A191G,kka2_1:8_191,Kka2,kka2_1:8,P00552,0.975501,NO,191,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.831,-3.024,2.193,,,,b,1.04,-0.94,1.306,,50,AHO,-0.868667,0.100394,0.00338807,0.975501 beta-lactamase_0_R242Y,beta-lactamase_0_242,TEM-1,beta-lactamase_0,P62593,0.975504,NO,242,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.0500837,0.00452879,0.975504 beta-lactamase_I243V,beta-lactamase_243,TEM-1,beta-lactamase,P62593,0.975508,NO,243,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.532,-2.311,0.779,5.26886,,E,B,1.68,-1.24,2.289,,50,OHH,-1.46867,0.221079,0.00464034,0.975508 Pab1_D138H,Pab1_138,Pab1,Pab1,P04147,0.975519,NO,138,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.128,-4.266,3.138,,0.427,,B,,-0.03,,,,HAP,-1.13967,0.175299,0.000567877,0.975519 beta-lactamase_39_H287T,beta-lactamase_39_287,TEM-1,beta-lactamase_39,P62593,0.975522,NO,287,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,,,,,,,,,,,,,BBH,-1.111,0.0495842,,0.975522 beta-lactamase_2500_G226H,beta-lactamase_2500_226,TEM-1,beta-lactamase_2500,P62593,0.975537,NO,226,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.461,-4.656,3.195,,0.701,T,l,0.29,-0.25,5.086,,74.48,HOH,-1.42933,0.361275,0.00665294,0.975537 gb1_T244I,gb1_244,gb1,gb1,P06654,0.975544,NO,244,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.637,-2.823,1.186,,,,,,,0.202,,11.83,PPA,-1.92567,0.177985,0.00222755,0.975544 beta-lactamase_39_D252S,beta-lactamase_39_252,TEM-1,beta-lactamase_39,P62593,0.975546,NO,252,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.0495842,0.00575769,0.975546 beta-lactamase_N168G,beta-lactamase_168,TEM-1,beta-lactamase,P62593,0.975547,NO,168,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-1.029,-3.01,1.981,5.42128,0.113,G,A,0.09,-0.4,1.211,,44.41,HPA,-1.13233,0.221079,0.00288667,0.975547 beta-lactamase_39_M180L,beta-lactamase_39_180,TEM-1,beta-lactamase_39,P62593,0.975559,NO,180,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-2.795,-3.19,0.395,,0.242,,B,0.55,-0.94,3.579,,77.62,PHO,-1.56433,0.0495842,0.00552048,0.975559 beta-lactamase_T147S,beta-lactamase_147,TEM-1,beta-lactamase,P62593,0.975561,NO,147,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.149,-2.487,1.338,5.37474,0.281,H,A,0.8,-0.68,2.838,,64.34,HPH,-1.456,0.221079,0.00226017,0.975561 beta-lactamase_2500_A225G,beta-lactamase_2500_225,TEM-1,beta-lactamase_2500,P62593,0.975569,NO,225,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.845,-2.827,0.982,,1,T,B,0.46,-0.38,0.551,,74.48,OHO,-1.39967,0.361275,0.00465057,0.975569 beta-lactamase_156_P217N,beta-lactamase_156_217,TEM-1,beta-lactamase_156,P62593,0.975574,NO,217,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-2.062,-2.997,0.935,,0.496,I,A,0.52,-0.33,2.303,,74.48,OOH,-1.64333,0.111618,0.00463211,0.975574 beta-lactamase_625_G154Q,beta-lactamase_625_154,TEM-1,beta-lactamase_625,P62593,0.975574,NO,154,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.823,-4.083,3.26,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.213352,0.00180205,0.975574 Pab1_N162Y,Pab1_162,Pab1,Pab1,P04147,0.975574,NO,162,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-2.313,-3.886,1.573,,0.681,T,A,,1.12,,,,APO,-1.532,0.175299,0.0030719,0.975574 kka2_1:4_P76L,kka2_1:4_76,Kka2,kka2_1:4,P00552,0.97558,NO,76,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.449,-2.705,1.256,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.168804,0.00625685,0.97558 beta-lactamase_39_D207C,beta-lactamase_39_207,TEM-1,beta-lactamase_39,P62593,0.975585,NO,207,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.064,-5.19,3.126,,0.409,H,A,0.75,0.12,14.511,14.511,77.62,HAH,-1.77033,0.0495842,0.00592942,0.975585 beta-lactamase_0_G142V,beta-lactamase_0_142,TEM-1,beta-lactamase_0,P62593,0.975588,NO,142,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.707,-3.751,3.044,,0.034,,p,0.29,-0.64,1.947,,64.69,OOO,-0.834,0.0500837,0.00060149,0.975588 beta-lactamase_0_M184K,beta-lactamase_0_184,TEM-1,beta-lactamase_0,P62593,0.975595,NO,184,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.593,-3.659,2.066,,,H,A,0.55,-0.87,13.292,13.292,62.94,HHH,-1.41,0.0500837,0.00356019,0.975595 beta-lactamase_39_L218G,beta-lactamase_39_218,TEM-1,beta-lactamase_39,P62593,0.975598,NO,218,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.391,-3.644,2.253,,,I,b,0.55,-0.53,2.038,,74.48,OHH,-1.58867,0.0495842,0.00618274,0.975598 beta-lactamase_0_H156F,beta-lactamase_0_156,TEM-1,beta-lactamase_0,P62593,0.9756,NO,156,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-3.156,-4.428,1.272,,0.753,S,A,0.17,-0.6,23.367,23.367,77.62,ABH,-1.932,0.0500837,0.00468596,0.9756 beta-lactamase_I11M,beta-lactamase_11,TEM-1,beta-lactamase,P62593,0.975602,NO,11,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.745,-4.211,2.466,,,,,,,3.135,,66.08,HHO,-1.79467,0.221079,0.00261325,0.975602 beta-lactamase_625_I171A,beta-lactamase_625_171,TEM-1,beta-lactamase_625,P62593,0.975612,NO,171,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-2.431,-2.242,-0.189,,0.361,,B,0.48,0.53,3.869,,77.62,HHO,-1.55533,0.213352,0.00623355,0.975612 beta-lactamase_156_R220I,beta-lactamase_156_220,TEM-1,beta-lactamase_156,P62593,0.975618,NO,220,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-0.942,-3.974,3.032,,0.295,I,A,1.2,-0.76,2.164,,74.48,HBP,-1.33633,0.111618,0.00232421,0.975618 beta-lactamase_0_Q86H,beta-lactamase_0_86,TEM-1,beta-lactamase_0,P62593,0.975625,NO,86,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.4,-4.718,2.318,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.0500837,0.00450027,0.975625 beta-lactamase_2500_K254C,beta-lactamase_2500_254,TEM-1,beta-lactamase_2500,P62593,0.975647,NO,254,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.361275,0.00369,0.975647 beta-lactamase_156_A40L,beta-lactamase_156_40,TEM-1,beta-lactamase_156,P62593,0.975651,NO,40,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.402,-3.399,1.997,,0.155,S,B,0.46,0.21,1.357,,73.78,OHB,-1.40267,0.111618,0.00490026,0.975651 beta-lactamase_0_R159P,beta-lactamase_0_159,TEM-1,beta-lactamase_0,P62593,0.975653,NO,159,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-0.94,-3.905,2.965,,0.316,,B,1.2,-0.55,1.426,,64.34,PBH,-1.011,0.0500837,0.00108472,0.975653 beta-lactamase_0_A183P,beta-lactamase_0_183,TEM-1,beta-lactamase_0,P62593,0.975654,NO,183,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.231,-3.812,2.581,,0.155,H,A,0.46,-0.91,1.48,,77.62,HHH,-1.53367,0.0500837,0.00296631,0.975654 beta-lactamase_2500_E145N,beta-lactamase_2500_145,TEM-1,beta-lactamase_2500,P62593,0.975662,NO,145,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.357,-3.655,1.298,,0.545,H,A,1.04,0.79,2.124,,77.62,BAH,-2.069,0.361275,0.00553285,0.975662 beta-lactamase_39_D83V,beta-lactamase_39_83,TEM-1,beta-lactamase_39,P62593,0.975667,NO,83,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.066,-3.762,2.696,,0.354,H,A,0.75,0.22,0.752,,48.95,HAH,-1.34733,0.0495842,0.00205968,0.975667 beta-lactamase_156_V82Y,beta-lactamase_156_82,TEM-1,beta-lactamase_156,P62593,0.975678,NO,82,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.325,-4.133,2.808,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.111618,0.00397046,0.975678 Pab1_D160R,Pab1_160,Pab1,Pab1,P04147,0.975678,NO,160,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.985,-3.75,2.765,,0.396,B,B,,1.12,,,,PAA,-1.30133,0.175299,0.000311977,0.975678 beta-lactamase_2500_I285Y,beta-lactamase_2500_285,TEM-1,beta-lactamase_2500,P62593,0.975682,NO,285,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.361275,0.101555,0.975682 beta-lactamase_2500_E108H,beta-lactamase_2500_108,TEM-1,beta-lactamase_2500,P62593,0.975688,NO,108,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.46,-4.53,3.07,,0.572,G,A,1.04,1.87,1.147,,72.73,PAB,-1.437,0.361275,0.00413372,0.975688 Pab1_G163D,Pab1_163,Pab1,Pab1,P04147,0.975691,NO,163,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.809,-3.286,2.477,,0.356,B,g,,0.55,,,,POB,-1.80667,0.175299,0.00030953,0.975691 beta-lactamase_E56N,beta-lactamase_56,TEM-1,beta-lactamase,P62593,0.975705,NO,56,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.043,-2.542,0.499,5.65281,0.198,E,B,0.52,0.31,2.022,,72.73,HAP,-1.94033,0.221079,0.00238534,0.975705 beta-lactamase_E56Q,beta-lactamase_56,TEM-1,beta-lactamase,P62593,0.975705,NO,56,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.043,-3.697,1.654,5.65281,0.198,E,B,0.52,0.31,2.022,,72.73,HAP,-1.94033,0.221079,0.00238534,0.975705 beta-lactamase_L247V,beta-lactamase_247,TEM-1,beta-lactamase,P62593,0.975705,NO,247,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.48,-2.101,0.621,5.28771,0.007,E,B,2.89,-0.72,2.951,,63.99,HHO,-1.79833,0.221079,0.00611275,0.975705 beta-lactamase_2500_I125V,beta-lactamase_2500_125,TEM-1,beta-lactamase_2500,P62593,0.975723,NO,125,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.441,-2.101,0.66,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.361275,0.00383964,0.975723 beta-lactamase_0_L219C,beta-lactamase_0_219,TEM-1,beta-lactamase_0,P62593,0.975724,NO,219,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.313,-3.103,1.79,,,I,A,0.55,-0.51,6.513,6.513,74.48,HHB,-1.21533,0.0500837,0.00664345,0.975724 beta-lactamase_0_D155G,beta-lactamase_0_155,TEM-1,beta-lactamase_0,P62593,0.975726,NO,155,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.889,-3.177,2.288,,0.049,,B,0.75,-0.9,16.833,16.833,64.69,OAB,-1.62267,0.0500837,0.00135315,0.975726 beta-lactamase_2500_S96I,beta-lactamase_2500_96,TEM-1,beta-lactamase_2500,P62593,0.975727,NO,96,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.27,-3.225,0.955,,0.368,,b,0.27,0.39,32.348,32.348,73.78,HPP,-2.019,0.361275,0.00551835,0.975727 beta-lactamase_2500_K53I,beta-lactamase_2500_53,TEM-1,beta-lactamase_2500,P62593,0.975728,NO,53,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-2.313,-4.015,1.702,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.361275,0.00383383,0.975728 beta-lactamase_39_R275D,beta-lactamase_39_275,TEM-1,beta-lactamase_39,P62593,0.975728,NO,275,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.0495842,0.0141984,0.975728 beta-lactamase_2500_E175S,beta-lactamase_2500_175,TEM-1,beta-lactamase_2500,P62593,0.975736,NO,175,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.336,-2.863,0.527,,0.551,,A,1.04,1.05,5.316,,77.62,AAB,-1.31233,0.361275,0.00482205,0.975736 beta-lactamase_2500_E272K,beta-lactamase_2500_272,TEM-1,beta-lactamase_2500,P62593,0.975739,NO,272,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.361275,0.00545371,0.975739 beta-lactamase_625_R273K,beta-lactamase_625_273,TEM-1,beta-lactamase_625,P62593,0.975745,NO,273,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.314,-2.204,-0.11,,0.564,H,A,1.2,1.57,1.455,,73.78,ABP,-1.841,0.213352,0.0077952,0.975745 kka2_1:4_D159E,kka2_1:4_159,Kka2,kka2_1:4,P00552,0.975755,NO,159,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.82,-2.917,2.097,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.168804,0.0030485,0.975755 beta-lactamase_S80R,beta-lactamase_80,TEM-1,beta-lactamase,P62593,0.975761,NO,80,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.029,-3.076,1.047,5.23748,0.192,H,A,0.25,0.46,2.256,,77.62,HPB,-1.44567,0.221079,0.00565569,0.975761 beta-lactamase_39_Q97N,beta-lactamase_39_97,TEM-1,beta-lactamase_39,P62593,0.975762,NO,97,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.072,-3.773,1.701,,0.823,G,A,0.64,2.42,4.457,,77.62,PPP,-2.43833,0.0495842,0.0045116,0.975762 beta-lactamase_156_V42I,beta-lactamase_156_42,TEM-1,beta-lactamase_156,P62593,0.975766,NO,42,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.564,-2.098,0.534,,0.017,E,B,0.44,-0.51,2.576,,63.99,BHO,-1.042,0.111618,0.00404515,0.975766 beta-lactamase_2500_Q88G,beta-lactamase_2500_88,TEM-1,beta-lactamase_2500,P62593,0.975773,NO,88,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.086,-3.448,1.362,,0.807,,B,0.64,2.03,1.84,,77.62,APH,-1.53433,0.361275,0.00504167,0.975773 beta-lactamase_2500_K213M,beta-lactamase_2500_213,TEM-1,beta-lactamase_2500,P62593,0.975779,NO,213,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.81,-4.653,2.843,,0.67,,A,2.34,0.29,1.668,,67.83,ABH,-1.57767,0.361275,0.00610411,0.975779 beta-lactamase_156_D252H,beta-lactamase_156_252,TEM-1,beta-lactamase_156,P62593,0.975796,NO,252,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.111618,0.00575769,0.975796 beta-lactamase_0_G236V,beta-lactamase_0_236,TEM-1,beta-lactamase_0,P62593,0.975799,NO,236,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.784,-3.686,2.902,,0.241,,b,0.29,-0.59,3.506,,64.69,HOO,-1.025,0.0500837,0.00162372,0.975799 Ubiquitin_A28A,Ubiquitin_28,Uba1,Ubiquitin,P0CG48,0.975806,NO,28,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.895,-1.895,0,4.73736,0.369,H,A,,-0.11,,,,BHB,-1.47667,0.205827,0.000842053,0.975806 Ubiquitin_A28C,Ubiquitin_28,Uba1,Ubiquitin,P0CG48,0.975806,NO,28,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.895,-4.995,3.1,4.73736,0.369,H,A,,-0.11,,,,BHB,-1.47667,0.205827,0.000842053,0.975806 Ubiquitin_A28N,Ubiquitin_28,Uba1,Ubiquitin,P0CG48,0.975806,NO,28,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.895,-3.765,1.87,4.73736,0.369,H,A,,-0.11,,,,BHB,-1.47667,0.205827,0.000842053,0.975806 Ubiquitin_A28Q,Ubiquitin_28,Uba1,Ubiquitin,P0CG48,0.975806,NO,28,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.895,-2.608,0.713,4.73736,0.369,H,A,,-0.11,,,,BHB,-1.47667,0.205827,0.000842053,0.975806 Ubiquitin_A28S,Ubiquitin_28,Uba1,Ubiquitin,P0CG48,0.975806,NO,28,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.895,-2.576,0.681,4.73736,0.369,H,A,,-0.11,,,,BHB,-1.47667,0.205827,0.000842053,0.975806 Ubiquitin_D21H,Ubiquitin_21,Uba1,Ubiquitin,P0CG48,0.975806,NO,21,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.193,-4.362,3.169,4.96432,0.165,,B,0.23,-0.53,1.013,,71.82,PAP,-1.35867,0.205827,0.000465257,0.975806 Ubiquitin_D21Q,Ubiquitin_21,Uba1,Ubiquitin,P0CG48,0.975806,NO,21,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.193,-3.692,2.499,4.96432,0.165,,B,0.23,-0.53,1.013,,71.82,PAP,-1.35867,0.205827,0.000465257,0.975806 Ubiquitin_D24C,Ubiquitin_24,Uba1,Ubiquitin,P0CG48,0.975806,NO,24,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,,,,,,,,,,,,,HAP,,0.205827,0.0066591,0.975806 Ubiquitin_D24D,Ubiquitin_24,Uba1,Ubiquitin,P0CG48,0.975806,NO,24,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,,,,,,,,,,,,,HAP,,0.205827,0.0066591,0.975806 Ubiquitin_D24T,Ubiquitin_24,Uba1,Ubiquitin,P0CG48,0.975806,NO,24,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,,,,,,,,,,,,,HAP,,0.205827,0.0066591,0.975806 Ubiquitin_D39L,Ubiquitin_39,Uba1,Ubiquitin,P0CG48,0.975806,NO,39,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.792,-3.595,1.803,5.1607,0.433,G,A,,0.55,,,,OAP,-1.754,0.205827,0.00071409,0.975806 Ubiquitin_D39N,Ubiquitin_39,Uba1,Ubiquitin,P0CG48,0.975806,NO,39,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.792,-2.602,0.81,5.1607,0.433,G,A,,0.55,,,,OAP,-1.754,0.205827,0.00071409,0.975806 Ubiquitin_E16C,Ubiquitin_16,Uba1,Ubiquitin,P0CG48,0.975806,NO,16,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.545,-5.245,3.7,5.07465,0.567,E,B,,0.59,,,,HAH,-1.31367,0.205827,0.000786769,0.975806 Ubiquitin_E16I,Ubiquitin_16,Uba1,Ubiquitin,P0CG48,0.975806,NO,16,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.545,-4.108,2.563,5.07465,0.567,E,B,,0.59,,,,HAH,-1.31367,0.205827,0.000786769,0.975806 Ubiquitin_E16R,Ubiquitin_16,Uba1,Ubiquitin,P0CG48,0.975806,NO,16,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.545,-3.574,2.029,5.07465,0.567,E,B,,0.59,,,,HAH,-1.31367,0.205827,0.000786769,0.975806 Ubiquitin_E18Y,Ubiquitin_18,Uba1,Ubiquitin,P0CG48,0.975806,NO,18,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.696,-4.219,2.523,5.04795,0.545,,B,,0.03,,,,HAO,-1.78733,0.205827,0.000623342,0.975806 Ubiquitin_E51G,Ubiquitin_51,Uba1,Ubiquitin,P0CG48,0.975806,NO,51,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.534,-2.591,1.057,5.36711,0.545,,B,,0.72,,,,HAA,-1.357,0.205827,0.000868134,0.975806 Ubiquitin_F45W,Ubiquitin_45,Uba1,Ubiquitin,P0CG48,0.975806,NO,45,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.322,-4.637,3.315,4.80693,0.26,E,B,1.62,-0.99,1.531,,53.87,HHH,-1.55267,0.205827,0.000470401,0.975806 Ubiquitin_G35A,Ubiquitin_35,Uba1,Ubiquitin,P0CG48,0.975806,NO,35,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.171,-2.99,1.819,4.96213,0.713,,L,,0.2,,,,AOH,-1.314,0.205827,0.000648878,0.975806 Ubiquitin_G47G,Ubiquitin_47,Uba1,Ubiquitin,P0CG48,0.975806,NO,47,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.423,-1.423,0,5.24944,0.057,T,l,,-1.21,,,,HOB,-1.543,0.205827,0.000471587,0.975806 Ubiquitin_I13V,Ubiquitin_13,Uba1,Ubiquitin,P0CG48,0.975806,NO,13,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.554,-2.378,0.824,5.19411,0.038,E,B,,-0.2,,,,PHP,-1.48,0.205827,0.000716423,0.975806 Ubiquitin_I23T,Ubiquitin_23,Uba1,Ubiquitin,P0CG48,0.975806,NO,23,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.325,-2.605,1.28,4.67534,,H,A,0.01,-0.93,0.515,,52.12,PHA,-1.54033,0.205827,0.000621252,0.975806 Ubiquitin_I23V,Ubiquitin_23,Uba1,Ubiquitin,P0CG48,0.975806,NO,23,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.325,-1.924,0.599,4.67534,,H,A,0.01,-0.93,0.515,,52.12,PHA,-1.54033,0.205827,0.000621252,0.975806 Ubiquitin_I44L,Ubiquitin_44,Uba1,Ubiquitin,P0CG48,0.975806,NO,44,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.566,-2.847,1.281,4.71256,,E,B,0.27,-1.17,5.26,,39.71,HHH,-1.38567,0.205827,0.000613305,0.975806 Ubiquitin_I61C,Ubiquitin_61,Uba1,Ubiquitin,P0CG48,0.975806,NO,61,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.514,-4.825,3.311,5.19922,0.038,,B,1,-0.76,1.953,,24.53,PHP,-1.70833,0.205827,0.000738268,0.975806 Ubiquitin_K29I,Ubiquitin_29,Uba1,Ubiquitin,P0CG48,0.975806,NO,29,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.471,-3.846,2.375,4.74832,0.355,H,A,,-0.06,,,,HBH,-1.52367,0.205827,0.000900239,0.975806 Ubiquitin_K29M,Ubiquitin_29,Uba1,Ubiquitin,P0CG48,0.975806,NO,29,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.471,-2.633,1.162,4.74832,0.355,H,A,,-0.06,,,,HBH,-1.52367,0.205827,0.000900239,0.975806 Ubiquitin_K29T,Ubiquitin_29,Uba1,Ubiquitin,P0CG48,0.975806,NO,29,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.471,-3.554,2.083,4.74832,0.355,H,A,,-0.06,,,,HBH,-1.52367,0.205827,0.000900239,0.975806 Ubiquitin_K29V,Ubiquitin_29,Uba1,Ubiquitin,P0CG48,0.975806,NO,29,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.471,-3.516,2.045,4.74832,0.355,H,A,,-0.06,,,,HBH,-1.52367,0.205827,0.000900239,0.975806 Ubiquitin_K33V,Ubiquitin_33,Uba1,Ubiquitin,P0CG48,0.975806,NO,33,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.283,-3.272,1.989,5.08526,0.64,H,A,1.82,1.2,1.509,,51.09,ABA,-1.34267,0.205827,0.000712743,0.975806 Ubiquitin_K63M,Ubiquitin_63,Uba1,Ubiquitin,P0CG48,0.975806,NO,63,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.635,-4.715,3.08,5.08297,0.721,T,B,,0.59,,,,PBA,-1.74467,0.205827,0.000607964,0.975806 Ubiquitin_K63N,Ubiquitin_63,Uba1,Ubiquitin,P0CG48,0.975806,NO,63,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.635,-2.376,0.741,5.08297,0.721,T,B,,0.59,,,,PBA,-1.74467,0.205827,0.000607964,0.975806 Ubiquitin_L15M,Ubiquitin_15,Uba1,Ubiquitin,P0CG48,0.975806,NO,15,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.082,-3.902,2.82,5.14718,0.029,E,B,1.16,-0.53,0.936,,38.69,PHA,-1.40833,0.205827,0.000519738,0.975806 Ubiquitin_L56M,Ubiquitin_56,Uba1,Ubiquitin,P0CG48,0.975806,NO,56,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.324,-3.006,1.682,4.83362,,T,A,,-0.91,,,,PHP,-1.60067,0.205827,0.000459465,0.975806 Ubiquitin_L67F,Ubiquitin_67,Uba1,Ubiquitin,P0CG48,0.975806,NO,67,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.435,-3.923,2.488,4.92156,,E,B,1.19,-1.02,6.371,6.371,30.8,PHB,-1.628,0.205827,0.000482727,0.975806 Ubiquitin_L69L,Ubiquitin_69,Uba1,Ubiquitin,P0CG48,0.975806,NO,69,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.445,-1.445,0,4.75624,0.051,E,B,2.89,-0.94,7.106,,34.31,BHH,-1.72933,0.205827,0.000919136,0.975806 Ubiquitin_N25C,Ubiquitin_25,Uba1,Ubiquitin,P0CG48,0.975806,NO,25,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-1.95,-5.072,3.122,4.76563,0.444,H,A,0.09,0,2.3,,31.09,APH,-1.741,0.205827,0.00071919,0.975806 Ubiquitin_N25G,Ubiquitin_25,Uba1,Ubiquitin,P0CG48,0.975806,NO,25,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-1.95,-2.437,0.487,4.76563,0.444,H,A,0.09,0,2.3,,31.09,APH,-1.741,0.205827,0.00071919,0.975806 Ubiquitin_N25H,Ubiquitin_25,Uba1,Ubiquitin,P0CG48,0.975806,NO,25,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-1.95,-3.213,1.263,4.76563,0.444,H,A,0.09,0,2.3,,31.09,APH,-1.741,0.205827,0.00071919,0.975806 Ubiquitin_N25K,Ubiquitin_25,Uba1,Ubiquitin,P0CG48,0.975806,NO,25,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-1.95,-2.597,0.647,4.76563,0.444,H,A,0.09,0,2.3,,31.09,APH,-1.741,0.205827,0.00071919,0.975806 Ubiquitin_N25M,Ubiquitin_25,Uba1,Ubiquitin,P0CG48,0.975806,NO,25,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-1.95,-3.315,1.365,4.76563,0.444,H,A,0.09,0,2.3,,31.09,APH,-1.741,0.205827,0.00071919,0.975806 Ubiquitin_N25V,Ubiquitin_25,Uba1,Ubiquitin,P0CG48,0.975806,NO,25,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-1.95,-3.564,1.614,4.76563,0.444,H,A,0.09,0,2.3,,31.09,APH,-1.741,0.205827,0.00071919,0.975806 Ubiquitin_N60D,Ubiquitin_60,Uba1,Ubiquitin,P0CG48,0.975806,NO,60,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-1.775,-2.583,0.808,5.00332,0.775,T,L,,0.33,,,,HPH,-1.532,0.205827,0.000814061,0.975806 Ubiquitin_P19F,Ubiquitin_19,Uba1,Ubiquitin,P0CG48,0.975806,NO,19,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-2.352,-3.157,0.805,4.67617,0.398,T,A,,-0.61,,,,AOP,-1.86233,0.205827,0.000729653,0.975806 Ubiquitin_P19K,Ubiquitin_19,Uba1,Ubiquitin,P0CG48,0.975806,NO,19,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-2.352,-3.583,1.231,4.67617,0.398,T,A,,-0.61,,,,AOP,-1.86233,0.205827,0.000729653,0.975806 Ubiquitin_Q31C,Ubiquitin_31,Uba1,Ubiquitin,P0CG48,0.975806,NO,31,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-1.678,-5.222,3.544,4.5004,0.464,H,A,,0.68,,,,HPA,-1.44467,0.205827,0.000724141,0.975806 Ubiquitin_Q31T,Ubiquitin_31,Uba1,Ubiquitin,P0CG48,0.975806,NO,31,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-1.678,-3.578,1.9,4.5004,0.464,H,A,,0.68,,,,HPA,-1.44467,0.205827,0.000724141,0.975806 Ubiquitin_Q31W,Ubiquitin_31,Uba1,Ubiquitin,P0CG48,0.975806,NO,31,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-1.678,-5.233,3.555,4.5004,0.464,H,A,,0.68,,,,HPA,-1.44467,0.205827,0.000724141,0.975806 Ubiquitin_Q31Y,Ubiquitin_31,Uba1,Ubiquitin,P0CG48,0.975806,NO,31,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-1.678,-2.964,1.286,4.5004,0.464,H,A,,0.68,,,,HPA,-1.44467,0.205827,0.000724141,0.975806 Ubiquitin_Q62P,Ubiquitin_62,Uba1,Ubiquitin,P0CG48,0.975806,NO,62,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-1.836,-2.977,1.141,5.33616,0.762,,B,,0.79,,,,HPB,-1.66167,0.205827,0.00068944,0.975806 Ubiquitin_R54C,Ubiquitin_54,Uba1,Ubiquitin,P0CG48,0.975806,NO,54,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.037,-3.345,1.308,5.14935,0.41,S,B,,0.87,,,,OBP,-1.72667,0.205827,0.000581095,0.975806 Ubiquitin_R54H,Ubiquitin_54,Uba1,Ubiquitin,P0CG48,0.975806,NO,54,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.037,-3.236,1.199,5.14935,0.41,S,B,,0.87,,,,OBP,-1.72667,0.205827,0.000581095,0.975806 Ubiquitin_R54K,Ubiquitin_54,Uba1,Ubiquitin,P0CG48,0.975806,NO,54,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.037,-2.574,0.537,5.14935,0.41,S,B,,0.87,,,,OBP,-1.72667,0.205827,0.000581095,0.975806 Ubiquitin_S65F,Ubiquitin_65,Uba1,Ubiquitin,P0CG48,0.975806,NO,65,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.535,-4.127,2.592,4.99442,0.168,,b,0.25,-0.68,16.756,16.756,33.87,APP,-1.626,0.205827,0.000546776,0.975806 Ubiquitin_T22T,Ubiquitin_22,Uba1,Ubiquitin,P0CG48,0.975806,NO,22,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.344,-1.344,,4.54389,0.237,B,B,,-0.75,,,,APH,-1.28733,0.205827,0.000535592,0.975806 Ubiquitin_T7S,Ubiquitin_7,Uba1,Ubiquitin,P0CG48,0.975806,NO,7,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.415,-2.524,1.109,4.954,0.094,E,B,0.43,-0.78,0.805,,21.31,BPH,-1.41033,0.205827,0.000647855,0.975806 Ubiquitin_T9A,Ubiquitin_9,Uba1,Ubiquitin,P0CG48,0.975806,NO,9,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.409,-2.945,1.536,5.24336,0.777,T,A,2.12,-0.12,2.705,,29.93,HPO,-1.50933,0.205827,0.000630716,0.975806 Ubiquitin_V17I,Ubiquitin_17,Uba1,Ubiquitin,P0CG48,0.975806,NO,17,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.314,-3.023,1.709,5.26282,0.017,,B,2.78,-0.77,3.239,,71.82,AHA,-1.51833,0.205827,0.000659638,0.975806 Ubiquitin_V26C,Ubiquitin_26,Uba1,Ubiquitin,P0CG48,0.975806,NO,26,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.321,-4.728,3.407,4.78447,,H,A,,-0.97,,,,PHB,-1.445,0.205827,0.000980269,0.975806 Ubiquitin_V26I,Ubiquitin_26,Uba1,Ubiquitin,P0CG48,0.975806,NO,26,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.321,-1.869,0.548,4.78447,,H,A,,-0.97,,,,PHB,-1.445,0.205827,0.000980269,0.975806 Ubiquitin_V26L,Ubiquitin_26,Uba1,Ubiquitin,P0CG48,0.975806,NO,26,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.321,-2.054,0.733,4.78447,,H,A,,-0.97,,,,PHB,-1.445,0.205827,0.000980269,0.975806 Ubiquitin_V5C,Ubiquitin_5,Uba1,Ubiquitin,P0CG48,0.975806,NO,5,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.576,-2.951,1.375,4.75677,,E,B,,-0.82,,,,HHB,-1.401,0.205827,0.000796998,0.975806 beta-lactamase_A77V,beta-lactamase_77,TEM-1,beta-lactamase,P62593,0.975812,NO,77,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.234,-2.654,1.42,4.75777,0.039,H,A,0.52,-0.56,1.708,,64.34,OHH,-1.294,0.221079,0.00282362,0.975812 beta-lactamase_C18S,beta-lactamase_18,TEM-1,beta-lactamase,P62593,0.975812,NO,18,C,S,CS,Special,Polar,5.07,5.68,0.61,112,121,105,-16,108.5,89,-19.5,-2.26,-2.385,0.125,,,,,,,3.995,,93.01,HOH,-2.093,0.221079,0.002536,0.975812 beta-lactamase_D113S,beta-lactamase_113,TEM-1,beta-lactamase,P62593,0.975812,NO,113,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.829,-2.84,1.011,6.04499,0.665,T,A,0.23,0.91,21.104,21.104,73.08,PAO,-1.703,0.221079,0.00474112,0.975812 beta-lactamase_E102V,beta-lactamase_102,TEM-1,beta-lactamase,P62593,0.975812,NO,102,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.118,-3.638,1.52,6.36157,0.722,S,B,1.5,1.82,1.336,,73.08,HAH,-1.581,0.221079,0.00486633,0.975812 beta-lactamase_L160L,beta-lactamase_160,TEM-1,beta-lactamase,P62593,0.975812,NO,160,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.977,-0.977,,5.32068,0.022,,B,1.75,-0.6,0.895,,44.41,BHA,-0.936,0.221079,0.00193775,0.975812 kka2_1:2_L103F,kka2_1:2_103,Kka2,kka2_1:2,P00552,0.975816,NO,103,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-2.362,-4.185,1.823,,0.394,T,A,0.55,-0.99,3.499,,63.64,HHP,-1.534,0.295029,0.00574792,0.975816 beta-lactamase_2500_T139N,beta-lactamase_2500_139,TEM-1,beta-lactamase_2500,P62593,0.975823,NO,139,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.901,-3.686,1.785,,0.216,H,A,0.22,0.39,2.256,,77.62,PPH,-2.04667,0.361275,0.00441837,0.975823 beta-lactamase_39_E62R,beta-lactamase_39_62,TEM-1,beta-lactamase_39,P62593,0.975825,NO,62,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.193,-3.663,2.47,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.0495842,0.00264802,0.975825 beta-lactamase_S80L,beta-lactamase_80,TEM-1,beta-lactamase,P62593,0.975829,NO,80,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.029,-2.857,0.828,5.23748,0.192,H,A,0.25,0.46,2.256,,77.62,HPB,-1.44567,0.221079,0.00565569,0.975829 kka2_1:4_G21L,kka2_1:4_21,Kka2,kka2_1:4,P00552,0.975843,NO,21,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.368,-3.794,2.426,,0.586,T,l,0.75,-0.75,3.075,,71.59,HOH,-2.10167,0.168804,0.00709648,0.975843 beta-lactamase_156_L199N,beta-lactamase_156_199,TEM-1,beta-lactamase_156,P62593,0.975851,NO,199,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-2.942,-3.124,0.182,,0.832,H,A,0.55,0.42,1.552,,77.62,PHH,-2.32933,0.111618,0.0048649,0.975851 beta-lactamase_2500_S80V,beta-lactamase_2500_80,TEM-1,beta-lactamase_2500,P62593,0.975854,NO,80,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.029,-2.695,0.666,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.361275,0.00565569,0.975854 beta-lactamase_39_Y103R,beta-lactamase_39_103,TEM-1,beta-lactamase_39,P62593,0.975854,NO,103,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-1.33,-3.864,2.534,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.0495842,0.00443048,0.975854 beta-lactamase_2500_L188V,beta-lactamase_2500_188,TEM-1,beta-lactamase_2500,P62593,0.975856,NO,188,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.166,-3.017,1.851,,,H,A,0.55,-0.3,17.865,17.865,60.14,PHB,-1.47033,0.361275,0.00295687,0.975856 beta-lactamase_39_L100S,beta-lactamase_39_100,TEM-1,beta-lactamase_39,P62593,0.975867,NO,100,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.218,-3.715,2.497,,0.343,,B,0.55,0.13,8.311,,63.29,AHH,-1.23467,0.0495842,0.00413885,0.975867 beta-lactamase_156_V42F,beta-lactamase_156_42,TEM-1,beta-lactamase_156,P62593,0.975871,NO,42,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.564,-3.895,2.331,,0.017,E,B,0.44,-0.51,2.576,,63.99,BHO,-1.042,0.111618,0.00404515,0.975871 beta-lactamase_E277V,beta-lactamase_277,TEM-1,beta-lactamase,P62593,0.975875,NO,277,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.869,-2.936,1.067,5.51786,0.545,H,A,0.52,-0.01,2.022,,77.62,HAH,-1.45367,0.221079,0.0169305,0.975875 beta-lactamase_625_V42A,beta-lactamase_625_42,TEM-1,beta-lactamase_625,P62593,0.975895,NO,42,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.564,-2.554,0.99,,0.017,E,B,0.44,-0.51,2.576,,63.99,BHO,-1.042,0.213352,0.00404515,0.975895 beta-lactamase_39_E56C,beta-lactamase_39_56,TEM-1,beta-lactamase_39,P62593,0.975901,NO,56,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.043,-4.827,2.784,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.0495842,0.00238534,0.975901 beta-lactamase_0_P255N,beta-lactamase_0_255,TEM-1,beta-lactamase_0,P62593,0.975917,NO,255,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.0500837,0.00499612,0.975917 beta-lactamase_156_K254W,beta-lactamase_156_254,TEM-1,beta-lactamase_156,P62593,0.975946,NO,254,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.111618,0.00369,0.975946 PSD95pdz3_S339I,PSD95pdz3_339,PSD95pdz3,PSD95pdz3,P31016,0.975948,NO,339,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.519,-3.467,1.948,5.34493,,,,,12.2167,,,,HPH,-1.55767,0.0758425,0.00084982,0.975948 beta-lactamase_156_L73D,beta-lactamase_156_73,TEM-1,beta-lactamase_156,P62593,0.975959,NO,73,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.507,-4.091,2.584,,,H,A,0.55,-0.64,2.09,,67.83,HHH,-1.487,0.111618,0.00488983,0.975959 beta-lactamase_625_A268I,beta-lactamase_625_268,TEM-1,beta-lactamase_625,P62593,0.975962,NO,268,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.213352,0.0102525,0.975962 beta-lactamase_0_E62L,beta-lactamase_0_62,TEM-1,beta-lactamase_0,P62593,0.975963,NO,62,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.193,-3.66,2.467,,0.342,S,B,1.04,-0.3,5.784,,73.08,AAB,-1.417,0.0500837,0.00264802,0.975963 kka2_1:2_N58S,kka2_1:2_58,Kka2,kka2_1:2,P00552,0.975964,NO,58,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-2.641,-1.901,-0.74,,0.131,S,A,0.43,0.72,5.729,,71.59,HPA,-1.83033,0.295029,0.00793425,0.975964 beta-lactamase_2500_K144R,beta-lactamase_2500_144,TEM-1,beta-lactamase_2500,P62593,0.97597,NO,144,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-2.388,-3.055,0.667,,0.863,H,A,2.34,1.27,0.515,,77.62,OBA,-1.904,0.361275,0.00481141,0.97597 beta-lactamase_39_K254L,beta-lactamase_39_254,TEM-1,beta-lactamase_39,P62593,0.975972,NO,254,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.0495842,0.00369,0.975972 beta-lactamase_0_L38T,beta-lactamase_0_38,TEM-1,beta-lactamase_0,P62593,0.975974,NO,38,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.343,-3.495,2.152,,0.088,H,A,0.55,0.2,13.556,13.556,64.34,PHO,-1.78033,0.0500837,0.00373244,0.975974 beta-lactamase_625_M180Y,beta-lactamase_625_180,TEM-1,beta-lactamase_625,P62593,0.975976,NO,180,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-2.795,-2.93,0.135,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.213352,0.00552048,0.975976 beta-lactamase_625_A170K,beta-lactamase_625_170,TEM-1,beta-lactamase_625,P62593,0.975995,NO,170,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.237,-3.643,2.406,,0.126,,L,0.46,-0.35,3.626,,64.69,AHH,-1.63267,0.213352,0.00431903,0.975995 beta-lactamase_D250T,beta-lactamase_250,TEM-1,beta-lactamase,P62593,0.976003,NO,250,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.335,-2.912,0.577,5.72026,0.89,T,L,0.23,1.53,24.737,24.737,66.08,OAO,-1.85133,0.221079,0.00550899,0.976003 beta-lactamase_156_Q203S,beta-lactamase_156_203,TEM-1,beta-lactamase_156,P62593,0.976007,NO,203,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.168,-2.824,0.656,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.111618,0.00631514,0.976007 kka2_1:8_H106L,kka2_1:8_106,Kka2,kka2_1:8,P00552,0.976014,NO,106,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-3.13,-2.804,-0.326,,1.065,,a,0.87,-0.95,15.956,15.956,71.59,PBH,-2.10433,0.100394,0.00730778,0.976014 kka2_1:8_H106L,kka2_1:8_106,Kka2,kka2_1:8,P00552,0.976014,NO,106,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-3.13,-2.804,-0.326,,1.065,,a,0.87,-0.95,15.956,15.956,71.59,PBH,-2.10433,0.100394,0.00730778,0.976014 beta-lactamase_0_K109M,beta-lactamase_0_109,TEM-1,beta-lactamase_0,P62593,0.976029,NO,109,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.734,-4.742,3.008,,0.787,G,A,2.34,2.21,15.473,15.473,72.73,ABB,-1.63333,0.0500837,0.00462493,0.976029 beta-lactamase_156_T178A,beta-lactamase_156_178,TEM-1,beta-lactamase_156,P62593,0.976033,NO,178,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-0.791,-2.853,2.062,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.111618,0.000684366,0.976033 beta-lactamase_M127F,beta-lactamase_127,TEM-1,beta-lactamase,P62593,0.976037,NO,127,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-2.251,-3.969,1.718,5.40552,0.312,S,A,1.07,0.32,1.671,,72.73,PHP,-1.40433,0.221079,0.00437927,0.976037 beta-lactamase_39_D271T,beta-lactamase_39_271,TEM-1,beta-lactamase_39,P62593,0.97604,NO,271,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.0495842,0.00752082,0.97604 beta-lactamase_2500_L111W,beta-lactamase_2500_111,TEM-1,beta-lactamase_2500,P62593,0.976046,NO,111,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.76,-5.305,3.545,,0.328,T,A,0.55,0.93,1.966,,64.34,BHP,-1.884,0.361275,0.00480671,0.976046 beta-lactamase_2500_D33V,beta-lactamase_2500_33,TEM-1,beta-lactamase_2500,P62593,0.976047,NO,33,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.321,-3.488,1.167,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.361275,0.00435556,0.976047 beta-lactamase_0_G85N,beta-lactamase_0_85,TEM-1,beta-lactamase_0,P62593,0.976072,NO,85,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.011,-3.501,2.49,,0.805,T,l,0.29,1.7,2.25,,63.64,HOP,-1.68733,0.0500837,0.00252173,0.976072 beta-lactamase_39_R176M,beta-lactamase_39_176,TEM-1,beta-lactamase_39,P62593,0.976079,NO,176,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-0.863,-4.48,3.617,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.0495842,0.00105554,0.976079 beta-lactamase_Q204H,beta-lactamase_204,TEM-1,beta-lactamase,P62593,0.976083,NO,204,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-1.382,-3.09,1.708,5.46394,0.204,H,A,0.12,0.09,1.707,,66.08,PPH,-1.49067,0.221079,0.00364106,0.976083 kka2_1:8_G10C,kka2_1:8_10,Kka2,kka2_1:8,P00552,0.976084,NO,10,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.921,-5.151,3.23,,,,,,,1.862,,71.59,HOP,-2.10733,0.100394,0.00289233,0.976084 kka2_1:8_G10C,kka2_1:8_10,Kka2,kka2_1:8,P00552,0.976084,NO,10,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.921,-5.151,3.23,,,,,,,1.862,,71.59,HOP,-2.10733,0.100394,0.00289233,0.976084 beta-lactamase_156_R59N,beta-lactamase_156_59,TEM-1,beta-lactamase_156,P62593,0.976087,NO,59,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.345,-2.533,1.188,,0.329,S,L,1.2,-0.09,2.995,,73.08,HBO,-2.24267,0.111618,0.00318082,0.976087 beta-lactamase_2500_V101L,beta-lactamase_2500_101,TEM-1,beta-lactamase_2500,P62593,0.976091,NO,101,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.295,-2.095,0.8,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.361275,0.00374492,0.976091 kka2_1:4_D156K,kka2_1:4_156,Kka2,kka2_1:4,P00552,0.976093,NO,156,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.696,-3.566,1.87,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.168804,0.00926998,0.976093 kka2_1:8_Q219N,kka2_1:8_219,Kka2,kka2_1:8,P00552,0.976102,NO,219,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-0.93,-3.499,2.569,,0.088,H,A,0.4,-0.85,0.897,,50,HPA,-1.05167,0.100394,0.00237913,0.976102 kka2_1:8_Q219N,kka2_1:8_219,Kka2,kka2_1:8,P00552,0.976102,NO,219,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-0.93,-3.499,2.569,,0.088,H,A,0.4,-0.85,0.897,,50,HPA,-1.05167,0.100394,0.00237913,0.976102 Pab1_A182T,Pab1_182,Pab1,Pab1,P04147,0.976102,NO,182,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.013,-3.014,2.001,,,H,A,0.17,0.79,,,,AHH,-1.36067,0.175299,0.000289034,0.976102 beta-lactamase_625_H287M,beta-lactamase_625_287,TEM-1,beta-lactamase_625,P62593,0.976103,NO,287,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,,,,,,,,,,,,,BBH,-1.111,0.213352,,0.976103 beta-lactamase_2500_M180V,beta-lactamase_2500_180,TEM-1,beta-lactamase_2500,P62593,0.976107,NO,180,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-2.795,-3.273,0.478,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.361275,0.00552048,0.976107 beta-lactamase_K109I,beta-lactamase_109,TEM-1,beta-lactamase,P62593,0.976115,NO,109,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.734,-4.102,2.368,6.05842,0.787,G,A,1.82,2.21,21.623,21.623,72.73,ABB,-1.63333,0.221079,0.00462493,0.976115 beta-lactamase_0_Q204F,beta-lactamase_0_204,TEM-1,beta-lactamase_0,P62593,0.976123,NO,204,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-1.382,-4.303,2.921,,0.204,H,A,0.64,0.09,2.646,,66.08,PPH,-1.49067,0.0500837,0.00364106,0.976123 beta-lactamase_39_R81N,beta-lactamase_39_81,TEM-1,beta-lactamase_39,P62593,0.976123,NO,81,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.466,-2.825,1.359,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.0495842,0.00499763,0.976123 beta-lactamase_39_K144G,beta-lactamase_39_144,TEM-1,beta-lactamase_39,P62593,0.976126,NO,144,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-2.388,-2.818,0.43,,0.863,H,A,2.34,1.27,14.556,14.556,77.62,OBA,-1.904,0.0495842,0.00481141,0.976126 beta-lactamase_156_I280C,beta-lactamase_156_280,TEM-1,beta-lactamase_156,P62593,0.976144,NO,280,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.111618,0.0530888,0.976144 beta-lactamase_2500_R59N,beta-lactamase_2500_59,TEM-1,beta-lactamase_2500,P62593,0.97616,NO,59,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.345,-2.533,1.188,,0.329,S,L,1.2,-0.09,3.719,,73.08,HBO,-2.24267,0.361275,0.00318082,0.97616 beta-lactamase_39_I45V,beta-lactamase_39_45,TEM-1,beta-lactamase_39,P62593,0.976167,NO,45,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-2.421,-2.178,-0.243,,,E,B,0.48,-0.3,2.256,,77.62,HHA,-2.30267,0.0495842,0.00452842,0.976167 beta-lactamase_39_P172Y,beta-lactamase_39_172,TEM-1,beta-lactamase_39,P62593,0.976177,NO,172,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.998,-4.368,3.37,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.0495842,0.00312594,0.976177 beta-lactamase_156_A268R,beta-lactamase_156_268,TEM-1,beta-lactamase_156,P62593,0.976182,NO,268,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.111618,0.0102525,0.976182 beta-lactamase_39_P25F,beta-lactamase_39_25,TEM-1,beta-lactamase_39,P62593,0.976189,NO,25,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.526,-4.406,2.88,,0.624,H,A,0.52,0.14,1.157,,73.08,BOA,-2.15367,0.0495842,0.00347571,0.976189 kka2_1:8_N200Y,kka2_1:8_200,Kka2,kka2_1:8,P00552,0.97619,NO,200,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-2.446,-4.44,1.994,,0.756,T,L,0.43,-0.08,2.528,,64.39,APO,-2.08,0.100394,0.00838549,0.97619 kka2_1:8_N200Y,kka2_1:8_200,Kka2,kka2_1:8,P00552,0.97619,NO,200,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-2.446,-4.44,1.994,,0.756,T,L,0.43,-0.08,2.528,,64.39,APO,-2.08,0.100394,0.00838549,0.97619 beta-lactamase_39_Q203D,beta-lactamase_39_203,TEM-1,beta-lactamase_39,P62593,0.976194,NO,203,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.168,-2.512,0.344,,0.47,H,A,0.64,-0.38,1.453,,65.38,BPP,-1.614,0.0495842,0.00631514,0.976194 beta-lactamase_156_M153I,beta-lactamase_156_153,TEM-1,beta-lactamase_156,P62593,0.976208,NO,153,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-3.193,-1.739,-1.454,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.111618,0.00509109,0.976208 beta-lactamase_39_D36R,beta-lactamase_39_36,TEM-1,beta-lactamase_39,P62593,0.976213,NO,36,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.732,-2.847,0.115,,0.555,H,A,0.75,1.17,13.689,13.689,77.62,AAP,-1.91167,0.0495842,0.00476483,0.976213 beta-lactamase_156_M180A,beta-lactamase_156_180,TEM-1,beta-lactamase_156,P62593,0.976235,NO,180,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-2.795,-2.974,0.179,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.111618,0.00552048,0.976235 beta-lactamase_156_R239T,beta-lactamase_156_239,TEM-1,beta-lactamase_156,P62593,0.976238,NO,239,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.111618,0.00213852,0.976238 beta-lactamase_2500_A222H,beta-lactamase_2500_222,TEM-1,beta-lactamase_2500,P62593,0.976249,NO,222,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.103,-2.705,0.602,,0.233,H,A,0.46,-0.25,0.379,,77.62,PHH,-1.63733,0.361275,0.00466094,0.976249 kka2_1:8_E169S,kka2_1:8_169,Kka2,kka2_1:8,P00552,0.976258,NO,169,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.996,-2.626,0.63,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.100394,0.00730086,0.976258 kka2_1:8_E169S,kka2_1:8_169,Kka2,kka2_1:8,P00552,0.976258,NO,169,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.996,-2.626,0.63,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.100394,0.00730086,0.976258 beta-lactamase_156_L111M,beta-lactamase_156_111,TEM-1,beta-lactamase_156,P62593,0.976259,NO,111,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.76,-4.22,2.46,,0.328,T,A,0.55,0.93,2.26,,64.34,BHP,-1.884,0.111618,0.00480671,0.976259 beta-lactamase_2500_D207C,beta-lactamase_2500_207,TEM-1,beta-lactamase_2500,P62593,0.976267,NO,207,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.064,-5.19,3.126,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.361275,0.00592942,0.976267 beta-lactamase_39_D83M,beta-lactamase_39_83,TEM-1,beta-lactamase_39,P62593,0.976269,NO,83,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.066,-4.912,3.846,,0.354,H,A,0.75,0.22,0.752,,48.95,HAH,-1.34733,0.0495842,0.00205968,0.976269 beta-lactamase_A276C,beta-lactamase_276,TEM-1,beta-lactamase,P62593,0.976277,NO,276,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.144,-4.632,3.488,5.1387,0.117,H,A,0.52,-0.84,1.283,,44.06,HHA,-1.47,0.221079,0.0191712,0.976277 beta-lactamase_L150M,beta-lactamase_150,TEM-1,beta-lactamase,P62593,0.976277,NO,150,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.326,-2.392,1.066,5.15566,,H,A,1.75,-0.2,1.615,,62.94,HHB,-1.86167,0.221079,0.00463171,0.976277 beta-lactamase_N152C,beta-lactamase_152,TEM-1,beta-lactamase,P62593,0.976277,NO,152,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-2.757,-5.071,2.314,5.98571,0.863,H,A,0.09,0.92,2.061,,77.62,BPH,-2.97,0.221079,0.00471429,0.976277 beta-lactamase_N152L,beta-lactamase_152,TEM-1,beta-lactamase,P62593,0.976277,NO,152,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-2.757,-3.55,0.793,5.98571,0.863,H,A,0.09,0.92,2.061,,77.62,BPH,-2.97,0.221079,0.00471429,0.976277 beta-lactamase_T139D,beta-lactamase_139,TEM-1,beta-lactamase,P62593,0.976277,NO,139,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.901,-3.596,1.695,5.69095,0.216,H,A,0.3,0.39,2.256,,77.62,PPH,-2.04667,0.221079,0.00441837,0.976277 beta-lactamase_0_T107A,beta-lactamase_0_107,TEM-1,beta-lactamase_0,P62593,0.976279,NO,107,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.117,-2.274,1.157,,,G,A,0.22,-0.06,3.73,,67.83,HPA,-1.265,0.0500837,0.00239347,0.976279 beta-lactamase_2500_H94A,beta-lactamase_2500_94,TEM-1,beta-lactamase_2500,P62593,0.976279,NO,94,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-2.5,-2.468,-0.032,,0.776,,B,0.17,1.24,1.176,,77.62,HBH,-1.872,0.361275,0.00389226,0.976279 PSD95pdz3_Q358K,PSD95pdz3_358,PSD95pdz3,PSD95pdz3,P31016,0.976287,NO,358,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-1.699,-2.689,0.99,5.21282,,,,,14.8844,,,,APH,-1.531,0.0758425,0.000594893,0.976287 beta-lactamase_625_L111Q,beta-lactamase_625_111,TEM-1,beta-lactamase_625,P62593,0.976302,NO,111,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.76,-3.108,1.348,,0.328,T,A,0.55,0.93,2.26,,64.34,BHP,-1.884,0.213352,0.00480671,0.976302 beta-lactamase_39_L89K,beta-lactamase_39_89,TEM-1,beta-lactamase_39,P62593,0.976311,NO,89,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.096,-3.669,2.573,,0.168,T,A,0.55,0.63,3.233,,64.34,PHO,-1.75767,0.0495842,0.00207068,0.976311 beta-lactamase_156_N168I,beta-lactamase_156_168,TEM-1,beta-lactamase_156,P62593,0.976315,NO,168,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-1.029,-3.943,2.914,,0.113,G,A,0.61,-0.4,1.014,,44.41,HPA,-1.13233,0.111618,0.00288667,0.976315 beta-lactamase_A84D,beta-lactamase_84,TEM-1,beta-lactamase,P62593,0.976323,NO,84,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.651,-2.92,1.269,5.28927,0.65,T,A,0.52,0.96,1.863,,68.18,AHO,-1.24267,0.221079,0.00503822,0.976323 kka2_1:8_P194S,kka2_1:8_194,Kka2,kka2_1:8,P00552,0.976332,NO,194,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.846,-2.623,1.777,,0.308,G,A,0.52,-1.19,4.861,,53.03,HOP,-0.888333,0.100394,0.00314194,0.976332 kka2_1:8_P194S,kka2_1:8_194,Kka2,kka2_1:8,P00552,0.976332,NO,194,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.846,-2.623,1.777,,0.308,G,A,0.52,-1.19,4.861,,53.03,HOP,-0.888333,0.100394,0.00314194,0.976332 kka2_1:8_R18L,kka2_1:8_18,Kka2,kka2_1:8,P00552,0.976332,NO,18,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.055,-2.54,0.485,,0.474,T,A,1.2,0.54,19.629,19.629,71.59,ABH,-1.821,0.100394,0.00724065,0.976332 kka2_1:8_R18L,kka2_1:8_18,Kka2,kka2_1:8,P00552,0.976332,NO,18,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.055,-2.54,0.485,,0.474,T,A,1.2,0.54,19.629,19.629,71.59,ABH,-1.821,0.100394,0.00724065,0.976332 beta-lactamase_625_D252M,beta-lactamase_625_252,TEM-1,beta-lactamase_625,P62593,0.976336,NO,252,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.213352,0.00575769,0.976336 kka2_1:4_A64N,kka2_1:4_64,Kka2,kka2_1:4,P00552,0.976336,NO,64,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.496,-4.101,2.605,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.168804,0.00705578,0.976336 beta-lactamase_2500_N152W,beta-lactamase_2500_152,TEM-1,beta-lactamase_2500,P62593,0.976344,NO,152,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-2.757,-5.472,2.715,,0.863,H,A,0.61,0.92,2.061,,77.62,BPH,-2.97,0.361275,0.00471429,0.976344 beta-lactamase_39_G39N,beta-lactamase_39_39,TEM-1,beta-lactamase_39,P62593,0.976344,NO,39,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.864,-2.55,0.686,,0.701,T,L,0.29,0.47,1.454,,77.62,HOH,-1.53633,0.0495842,0.00487611,0.976344 beta-lactamase_R271T,beta-lactamase_271,TEM-1,beta-lactamase,P62593,0.976378,NO,271,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.249,-2.421,1.172,5.24516,0.085,H,A,1.67,-0.05,0.474,,63.99,ABP,-1.36633,0.221079,0.00752082,0.976378 beta-lactamase_39_W227S,beta-lactamase_39_227,TEM-1,beta-lactamase_39,P62593,0.976381,NO,227,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-0.982,-3.768,2.786,,0.272,,B,0.47,-0.29,1.37,,74.48,OHH,-1.595,0.0495842,0.00226019,0.976381 PSD95pdz3_G383D,PSD95pdz3_383,PSD95pdz3,PSD95pdz3,P31016,0.976385,NO,383,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.008,-3.15,2.142,5.17213,,,,,20.5325,,,,HOP,-1.338,0.0758425,0.000233044,0.976385 beta-lactamase_156_A282N,beta-lactamase_156_282,TEM-1,beta-lactamase_156,P62593,0.976389,NO,282,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.111618,0.0449821,0.976389 beta-lactamase_0_G243T,beta-lactamase_0_243,TEM-1,beta-lactamase_0,P62593,0.97639,NO,243,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.0500837,0.00464034,0.97639 beta-lactamase_625_R63I,beta-lactamase_625_63,TEM-1,beta-lactamase_625,P62593,0.976402,NO,63,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-0.943,-3.824,2.881,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.213352,0.00126938,0.976402 beta-lactamase_2500_H156V,beta-lactamase_2500_156,TEM-1,beta-lactamase_2500,P62593,0.976403,NO,156,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-3.156,-3.735,0.579,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.361275,0.00468596,0.976403 beta-lactamase_K213I,beta-lactamase_213,TEM-1,beta-lactamase,P62593,0.976404,NO,213,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.81,-4.142,2.332,5.63167,0.67,,A,1.59,0.29,3.924,,67.83,ABH,-1.57767,0.221079,0.00610411,0.976404 beta-lactamase_39_A222N,beta-lactamase_39_222,TEM-1,beta-lactamase_39,P62593,0.976421,NO,222,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.103,-3.751,1.648,,0.233,H,A,0.46,-0.25,1.448,,77.62,PHH,-1.63733,0.0495842,0.00466094,0.976421 beta-lactamase_156_G265H,beta-lactamase_156_265,TEM-1,beta-lactamase_156,P62593,0.976429,NO,265,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.111618,0.00811926,0.976429 beta-lactamase_156_R239K,beta-lactamase_156_239,TEM-1,beta-lactamase_156,P62593,0.976437,NO,239,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.111618,0.00213852,0.976437 Pab1_A182S,Pab1_182,Pab1,Pab1,P04147,0.976438,NO,182,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.013,-2.753,1.74,,,H,A,0.17,0.79,,,,AHH,-1.36067,0.175299,0.000289034,0.976438 beta-lactamase_156_R81M,beta-lactamase_156_81,TEM-1,beta-lactamase_156,P62593,0.976442,NO,81,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.466,-4.579,3.113,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.111618,0.00499763,0.976442 beta-lactamase_625_D33F,beta-lactamase_625_33,TEM-1,beta-lactamase_625,P62593,0.976443,NO,33,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.321,-4.288,1.967,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.213352,0.00435556,0.976443 beta-lactamase_G90I,beta-lactamase_90,TEM-1,beta-lactamase,P62593,0.976448,NO,90,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-2.091,-4.052,1.961,5.51991,0.598,T,A,0.23,0.32,1.791,,77.62,HOB,-1.52633,0.221079,0.00490273,0.976448 beta-lactamase_H110Y,beta-lactamase_110,TEM-1,beta-lactamase,P62593,0.976448,NO,110,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-1.706,-2.513,0.807,5.52635,0.341,G,a,0.35,1.08,31.31,31.31,64.69,BBH,-1.73333,0.221079,0.00441499,0.976448 beta-lactamase_R271A,beta-lactamase_271,TEM-1,beta-lactamase,P62593,0.976448,NO,271,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.249,-3.142,1.893,5.24516,0.085,H,A,1.67,-0.05,0.474,,63.99,ABP,-1.36633,0.221079,0.00752082,0.976448 beta-lactamase_T112T,beta-lactamase_112,TEM-1,beta-lactamase,P62593,0.976448,NO,112,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.186,-2.186,,6.47162,0.921,T,A,0.77,1.06,2.04,,73.78,HPA,-1.925,0.221079,0.00531334,0.976448 beta-lactamase_156_V82D,beta-lactamase_156_82,TEM-1,beta-lactamase_156,P62593,0.976452,NO,82,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.325,-3.879,2.554,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.111618,0.00397046,0.976452 gb1_I232C,gb1_232,gb1,gb1,P06654,0.976478,NO,232,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-2.175,-4.61,2.435,,,,,,,0.766,,44.87,HHH,-2.152,0.177985,0.00580459,0.976478 beta-lactamase_L73A,beta-lactamase_73,TEM-1,beta-lactamase,P62593,0.976483,NO,73,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.507,-2.475,0.968,5.84139,,H,A,1.75,-0.64,2.09,,67.83,HHH,-1.487,0.221079,0.00488983,0.976483 beta-lactamase_156_D161H,beta-lactamase_156_161,TEM-1,beta-lactamase_156,P62593,0.976491,NO,161,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.891,-4.479,3.588,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.111618,0.000897697,0.976491 Pab1_L191S,Pab1_191,Pab1,Pab1,P04147,0.976502,NO,191,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.2,-3.424,2.224,,0.204,E,B,,2.24,,,,HHP,-1.20133,0.175299,0.000583797,0.976502 beta-lactamase_2500_N274D,beta-lactamase_2500_274,TEM-1,beta-lactamase_2500,P62593,0.976521,NO,274,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.361275,0.0110418,0.976521 beta-lactamase_39_D83Y,beta-lactamase_39_83,TEM-1,beta-lactamase_39,P62593,0.976521,NO,83,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.066,-4.396,3.33,,0.354,H,A,0.75,0.22,0.752,,48.95,HAH,-1.34733,0.0495842,0.00205968,0.976521 beta-lactamase_156_A148C,beta-lactamase_156_148,TEM-1,beta-lactamase_156,P62593,0.976523,NO,148,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.757,-5.042,3.285,,0.379,H,A,0.46,-0.55,3.551,,72.73,PHH,-1.40167,0.111618,0.00547053,0.976523 beta-lactamase_2500_Q97W,beta-lactamase_2500_97,TEM-1,beta-lactamase_2500,P62593,0.976524,NO,97,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.072,-5.457,3.385,,0.823,G,A,0.64,2.42,1.157,,77.62,PPP,-2.43833,0.361275,0.0045116,0.976524 Pab1_L186C,Pab1_186,Pab1,Pab1,P04147,0.976524,NO,186,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.783,-4.583,2.8,,,,,,,,,,HHP,-1.56967,0.175299,0.00154968,0.976524 kka2_1:1_Q27N,kka2_1:1_27,Kka2,kka2_1:1,P00552,0.976527,NO,27,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-1.659,-3.726,2.067,,0.608,.,A,0.64,0.71,0.521,,65.53,PPP,-1.90733,0.520039,0.00595365,0.976527 beta-lactamase_E210K,beta-lactamase_210,TEM-1,beta-lactamase,P62593,0.976536,NO,210,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.319,-2.868,0.549,5.7398,0.476,H,A,0.52,0.75,1.555,,77.62,HAH,-1.88567,0.221079,0.00663582,0.976536 beta-lactamase_R189N,beta-lactamase_189,TEM-1,beta-lactamase,P62593,0.976536,NO,189,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.844,-3.633,1.789,5.74877,0.278,H,A,0.68,1.01,1.512,,72.73,HBB,-1.668,0.221079,0.0050699,0.976536 beta-lactamase_R41M,beta-lactamase_41,TEM-1,beta-lactamase,P62593,0.976536,NO,41,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-0.942,-4.506,3.564,5.69185,0.321,E,B,0.91,-0.07,4.357,,65.03,HBH,-1.30267,0.221079,0.00123327,0.976536 beta-lactamase_2500_L111Y,beta-lactamase_2500_111,TEM-1,beta-lactamase_2500,P62593,0.976544,NO,111,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.76,-4.039,2.279,,0.328,T,A,0.55,0.93,1.966,,64.34,BHP,-1.884,0.361275,0.00480671,0.976544 beta-lactamase_156_S283T,beta-lactamase_156_283,TEM-1,beta-lactamase_156,P62593,0.976549,NO,283,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.111618,0.0429138,0.976549 beta-lactamase_2500_N152I,beta-lactamase_2500_152,TEM-1,beta-lactamase_2500,P62593,0.976549,NO,152,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-2.757,-3.192,0.435,,0.863,H,A,0.61,0.92,2.061,,77.62,BPH,-2.97,0.361275,0.00471429,0.976549 beta-lactamase_2500_M153T,beta-lactamase_2500_153,TEM-1,beta-lactamase_2500,P62593,0.97655,NO,153,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-3.193,-2.237,-0.956,,0.14,T,A,0.55,-0.11,3.409,,77.62,PHO,-2.25767,0.361275,0.00509109,0.97655 beta-lactamase_625_K144D,beta-lactamase_625_144,TEM-1,beta-lactamase_625,P62593,0.976575,NO,144,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-2.388,-3.584,1.196,,0.863,H,A,2.34,1.27,2.313,,77.62,OBA,-1.904,0.213352,0.00481141,0.976575 beta-lactamase_A9G,beta-lactamase_9,TEM-1,beta-lactamase,P62593,0.97659,NO,9,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.147,-3.454,1.307,,,,,,,5.128,,72.73,HHH,-2.04267,0.221079,0.00247263,0.97659 beta-lactamase_39_Q204W,beta-lactamase_39_204,TEM-1,beta-lactamase_39,P62593,0.976612,NO,204,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-1.382,-5.303,3.921,,0.204,H,A,0.64,0.09,0.489,,66.08,PPH,-1.49067,0.0495842,0.00364106,0.976612 beta-lactamase_39_S80T,beta-lactamase_39_80,TEM-1,beta-lactamase_39,P62593,0.97662,NO,80,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.029,-2.845,0.816,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.0495842,0.00565569,0.97662 beta-lactamase_K213V,beta-lactamase_213,TEM-1,beta-lactamase,P62593,0.976626,NO,213,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.81,-3.705,1.895,5.63167,0.67,,A,1.59,0.29,3.924,,67.83,ABH,-1.57767,0.221079,0.00610411,0.976626 beta-lactamase_S122W,beta-lactamase_122,TEM-1,beta-lactamase,P62593,0.976626,NO,122,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.406,-5.469,3.063,4.87767,0.352,H,A,0.73,-0.54,1.581,,77.62,OPH,-1.39767,0.221079,0.00497825,0.976626 beta-lactamase_156_D48T,beta-lactamase_156_48,TEM-1,beta-lactamase_156,P62593,0.97663,NO,48,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.101,-3.511,2.41,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.111618,0.0027273,0.97663 PSD95pdz3_A347S,PSD95pdz3_347,PSD95pdz3,PSD95pdz3,P31016,0.976631,NO,347,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.307,-2.617,1.31,4.89689,,,,,15.176,,,,OHA,-1.269,0.0758425,0.00074525,0.976631 beta-lactamase_39_A247Y,beta-lactamase_39_247,TEM-1,beta-lactamase_39,P62593,0.976638,NO,247,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.0495842,0.00611275,0.976638 beta-lactamase_156_E62K,beta-lactamase_156_62,TEM-1,beta-lactamase_156,P62593,0.976645,NO,62,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.193,-3.246,2.053,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.111618,0.00264802,0.976645 beta-lactamase_2500_G253H,beta-lactamase_2500_253,TEM-1,beta-lactamase_2500,P62593,0.976648,NO,253,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.361275,0.00786358,0.976648 beta-lactamase_39_R239D,beta-lactamase_39_239,TEM-1,beta-lactamase_39,P62593,0.97665,NO,239,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.0495842,0.00213852,0.97665 beta-lactamase_39_A170L,beta-lactamase_39_170,TEM-1,beta-lactamase_39,P62593,0.976659,NO,170,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.237,-3.289,2.052,,0.126,,L,0.46,-0.35,3.7,,64.69,AHH,-1.63267,0.0495842,0.00431903,0.976659 kka2_1:2_V198C,kka2_1:2_198,Kka2,kka2_1:2,P00552,0.976677,NO,198,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.719,-4.752,3.033,,0.05,E,B,1.48,-0.95,1.074,,56.06,HHA,-1.88667,0.295029,0.00835002,0.976677 beta-lactamase_156_D252L,beta-lactamase_156_252,TEM-1,beta-lactamase_156,P62593,0.976684,NO,252,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.111618,0.00575769,0.976684 kka2_1:2_D33L,kka2_1:2_33,Kka2,kka2_1:2,P00552,0.976688,NO,33,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.186,-3.734,1.548,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.295029,0.00633568,0.976688 beta-lactamase_156_S122F,beta-lactamase_156_122,TEM-1,beta-lactamase_156,P62593,0.976693,NO,122,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.406,-3.279,0.873,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.111618,0.00497825,0.976693 beta-lactamase_156_P60Q,beta-lactamase_156_60,TEM-1,beta-lactamase_156,P62593,0.976711,NO,60,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-2.469,-3.986,1.517,,0.256,T,A,0.52,-0.56,2.947,,77.62,BOA,-1.97633,0.111618,0.00521318,0.976711 kka2_1:4_L123R,kka2_1:4_123,Kka2,kka2_1:4,P00552,0.976714,NO,123,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.888,-4.001,3.113,,0.007,H,A,0.55,-0.4,1.447,,48.86,BHB,-1.301,0.168804,0.00325188,0.976714 PSD95pdz3_A382M,PSD95pdz3_382,PSD95pdz3,PSD95pdz3,P31016,0.976714,NO,382,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.307,-4.162,2.855,5.30282,,,,,22.472,,,,PHO,-1.24167,0.0758425,0.000249256,0.976714 beta-lactamase_39_V42I,beta-lactamase_39_42,TEM-1,beta-lactamase_39,P62593,0.976721,NO,42,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.564,-2.098,0.534,,0.017,E,B,0.44,-0.51,1.86,,63.99,BHO,-1.042,0.0495842,0.00404515,0.976721 beta-lactamase_39_S221N,beta-lactamase_39_221,TEM-1,beta-lactamase_39,P62593,0.976724,NO,221,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.754,-3.696,1.942,,0.624,H,A,0.27,-0.2,2.69,,74.48,BPH,-1.59967,0.0495842,0.0046094,0.976724 beta-lactamase_0_I261C,beta-lactamase_0_261,TEM-1,beta-lactamase_0,P62593,0.976729,NO,261,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.0500837,0.0123091,0.976729 beta-lactamase_156_L89K,beta-lactamase_156_89,TEM-1,beta-lactamase_156,P62593,0.976733,NO,89,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.096,-3.669,2.573,,0.168,T,A,0.55,0.63,2.633,,64.34,PHO,-1.75767,0.111618,0.00207068,0.976733 beta-lactamase_2500_M270L,beta-lactamase_2500_270,TEM-1,beta-lactamase_2500,P62593,0.976735,NO,270,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.723,,,,0.422,H,A,1.59,1.15,2.029,,64.34,PHA,-1.70933,0.361275,0.00767762,0.976735 beta-lactamase_0_S241K,beta-lactamase_0_241,TEM-1,beta-lactamase_0,P62593,0.976738,NO,241,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.0500837,0.00452736,0.976738 beta-lactamase_39_A170G,beta-lactamase_39_170,TEM-1,beta-lactamase_39,P62593,0.97674,NO,170,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.237,-1.884,0.647,,0.126,,L,0.46,-0.35,3.7,,64.69,AHH,-1.63267,0.0495842,0.00431903,0.97674 beta-lactamase_39_L196E,beta-lactamase_39_196,TEM-1,beta-lactamase_39,P62593,0.976751,NO,196,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-2.478,-3.033,0.555,,0.518,S,A,0.55,1.35,12.152,12.152,77.62,AHH,-1.839,0.0495842,0.00512144,0.976751 beta-lactamase_0_N274V,beta-lactamase_0_274,TEM-1,beta-lactamase_0,P62593,0.976753,NO,274,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.0500837,0.0110418,0.976753 beta-lactamase_156_T187Y,beta-lactamase_156_187,TEM-1,beta-lactamase_156,P62593,0.976758,NO,187,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.401,-4.271,2.87,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.111618,0.00491782,0.976758 beta-lactamase_625_D48S,beta-lactamase_625_48,TEM-1,beta-lactamase_625,P62593,0.976764,NO,48,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.101,-3.25,2.149,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.213352,0.0027273,0.976764 beta-lactamase_39_H287Y,beta-lactamase_39_287,TEM-1,beta-lactamase_39,P62593,0.976774,NO,287,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,,,,,,,,,,,,,BBH,-1.111,0.0495842,,0.976774 PSD95pdz3_N369G,PSD95pdz3_369,PSD95pdz3,PSD95pdz3,P31016,0.976774,NO,369,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-1.572,-2.685,1.113,5.91569,,,,,24.1262,0.44,,87.71,BPH,-1.487,0.0758425,0.000608412,0.976774 beta-lactamase_2500_T269Q,beta-lactamase_2500_269,TEM-1,beta-lactamase_2500,P62593,0.976787,NO,269,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.361275,0.00950944,0.976787 beta-lactamase_156_E166F,beta-lactamase_156_166,TEM-1,beta-lactamase_156,P62593,0.976792,NO,166,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.756,-4.345,2.589,,0.508,G,A,1.04,1.05,2.393,,73.08,OAH,-1.42233,0.111618,0.00512989,0.976792 beta-lactamase_2500_T264V,beta-lactamase_2500_264,TEM-1,beta-lactamase_2500,P62593,0.976803,NO,264,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.361275,0.0119399,0.976803 beta-lactamase_625_M66G,beta-lactamase_625_66,TEM-1,beta-lactamase_625,P62593,0.976804,NO,66,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.362,-3.751,2.389,,0.013,,A,0.55,-0.7,1.659,,73.08,OHH,-1.49567,0.213352,0.00412876,0.976804 beta-lactamase_156_H151Y,beta-lactamase_156_151,TEM-1,beta-lactamase_156,P62593,0.976809,NO,151,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-2.96,-4.115,1.155,,0.594,H,A,0.17,0.1,1.401,,77.62,HBP,-2.34767,0.111618,0.00216946,0.976809 beta-lactamase_156_H287E,beta-lactamase_156_287,TEM-1,beta-lactamase_156,P62593,0.976812,NO,287,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,,,,,,,,,,,,,BBH,-1.111,0.111618,,0.976812 beta-lactamase_G226H,beta-lactamase_226,TEM-1,beta-lactamase,P62593,0.976814,NO,226,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.461,-4.656,3.195,5.70682,0.701,T,l,0.77,-0.25,3.199,,74.48,HOH,-1.42933,0.221079,0.00665294,0.976814 beta-lactamase_Q37C,beta-lactamase_37,TEM-1,beta-lactamase,P62593,0.976814,NO,37,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.134,-5.133,2.999,5.69153,0.613,H,A,0.12,1.98,1.318,,73.08,APH,-2.06967,0.221079,0.00425833,0.976814 beta-lactamase_V101A,beta-lactamase_101,TEM-1,beta-lactamase,P62593,0.976814,NO,101,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.295,-3.114,1.819,5.49045,0.342,,B,0.96,0,1.675,,73.08,HHA,-1.54367,0.221079,0.00374492,0.976814 beta-lactamase_625_A230V,beta-lactamase_625_230,TEM-1,beta-lactamase_625,P62593,0.976818,NO,230,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.154,-3.38,2.226,,0.01,E,B,0.46,-1.17,0.777,,50,HHA,-1.079,0.213352,0.00516841,0.976818 kka2_1:4_L94V,kka2_1:4_94,Kka2,kka2_1:4,P00552,0.976831,NO,94,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.618,-2.483,0.865,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.168804,0.00520888,0.976831 kka2_1:4_D90Q,kka2_1:4_90,Kka2,kka2_1:4,P00552,0.97684,NO,90,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.459,-2.781,0.322,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.168804,0.00583842,0.97684 beta-lactamase_156_Q86L,beta-lactamase_156_86,TEM-1,beta-lactamase_156,P62593,0.97686,NO,86,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.4,-2.558,0.158,,0.696,S,A,0.64,2.38,27.704,27.704,77.62,OPA,-1.61067,0.111618,0.00450027,0.97686 beta-lactamase_625_T187H,beta-lactamase_625_187,TEM-1,beta-lactamase_625,P62593,0.976868,NO,187,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.401,-4.688,3.287,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.213352,0.00491782,0.976868 hsp90_Q582N,hsp90_582,hsp90,hsp90,P02829,0.976868,NO,582,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-3.278,-3.051,0,4.91603,0.453,S,B,,0.67,,,,OPH,-3.249,0.368192,0.000222939,0.976868 beta-lactamase_39_L284N,beta-lactamase_39_284,TEM-1,beta-lactamase_39,P62593,0.976872,NO,284,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.0495842,0.0686156,0.976872 Pab1_S147H,Pab1_147,Pab1,Pab1,P04147,0.976873,NO,147,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.267,-4.376,3.109,,0.336,H,A,,0.56,,,,HPH,-1.43033,0.175299,0.000610856,0.976873 beta-lactamase_156_G90D,beta-lactamase_156_90,TEM-1,beta-lactamase_156,P62593,0.976874,NO,90,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-2.091,-2.02,-0.071,,0.598,T,A,0.29,0.32,0.319,,77.62,HOB,-1.52633,0.111618,0.00490273,0.976874 beta-lactamase_156_E102L,beta-lactamase_156_102,TEM-1,beta-lactamase_156,P62593,0.976879,NO,102,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.118,-3.618,1.5,,0.722,S,B,1.04,1.82,15.721,15.721,73.08,HAH,-1.581,0.111618,0.00486633,0.976879 beta-lactamase_156_L79Q,beta-lactamase_156_79,TEM-1,beta-lactamase_156,P62593,0.97688,NO,79,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.842,-4.087,3.245,,0.007,H,A,0.55,-0.16,1.831,,50.35,HHP,-1.44333,0.111618,0.000947397,0.97688 beta-lactamase_625_T269K,beta-lactamase_625_269,TEM-1,beta-lactamase_625,P62593,0.976882,NO,269,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.213352,0.00950944,0.976882 WW_domain_R187A,WW_domain_187,Yap65,WW_domain,P46937,0.976892,NO,187,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.402,-2.918,1.516,5.05189,,,,,,3.431,,78.57,PBH,-1.362,0.153962,0.00171149,0.976892 kka2_1:8_E182A,kka2_1:8_182,Kka2,kka2_1:8,P00552,0.976896,NO,182,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.516,-2.542,1.026,,0.326,,B,1.52,0.75,2.568,,65.53,OAA,-1.806,0.100394,0.00641548,0.976896 kka2_1:8_E182A,kka2_1:8_182,Kka2,kka2_1:8,P00552,0.976896,NO,182,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.516,-2.542,1.026,,0.326,,B,1.52,0.75,2.568,,65.53,OAA,-1.806,0.100394,0.00641548,0.976896 beta-lactamase_156_T178Q,beta-lactamase_156_178,TEM-1,beta-lactamase_156,P62593,0.97691,NO,178,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-0.791,-3.899,3.108,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.111618,0.000684366,0.97691 PSD95pdz3_D332G,PSD95pdz3_332,PSD95pdz3,PSD95pdz3,P31016,0.976912,NO,332,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.264,-2.815,1.551,6.09878,,,,,48.762,,,,AAO,-1.22533,0.0758425,0.000937818,0.976912 beta-lactamase_39_M115N,beta-lactamase_39_115,TEM-1,beta-lactamase_39,P62593,0.976917,NO,115,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.389,-4.013,2.624,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.0495842,0.0034337,0.976917 beta-lactamase_39_E175I,beta-lactamase_39_175,TEM-1,beta-lactamase_39,P62593,0.976922,NO,175,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.336,-3.797,1.461,,0.551,,A,1.04,1.05,3.676,,77.62,AAB,-1.31233,0.0495842,0.00482205,0.976922 beta-lactamase_625_T27P,beta-lactamase_625_27,TEM-1,beta-lactamase_625,P62593,0.976931,NO,27,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.905,-1.921,0.016,,0.007,H,A,0.22,-0.37,3.72,,93.01,APH,-1.97933,0.213352,0.00306559,0.976931 beta-lactamase_39_A215I,beta-lactamase_39_215,TEM-1,beta-lactamase_39,P62593,0.976933,NO,215,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.503,-3.916,2.413,,,,a,0.46,-0.93,0.494,,74.48,HHO,-1.42633,0.0495842,0.00544007,0.976933 beta-lactamase_2500_Q97M,beta-lactamase_2500_97,TEM-1,beta-lactamase_2500,P62593,0.976936,NO,97,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.072,-3.413,1.341,,0.823,G,A,0.64,2.42,1.157,,77.62,PPP,-2.43833,0.361275,0.0045116,0.976936 beta-lactamase_39_L146Q,beta-lactamase_39_146,TEM-1,beta-lactamase_39,P62593,0.976946,NO,146,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.462,-4.29,2.828,,0.007,H,A,0.55,-0.56,1.953,,64.69,AHP,-1.656,0.0495842,0.00474542,0.976946 kka2_1:1_A13E,kka2_1:1_13,Kka2,kka2_1:1,P00552,0.976946,NO,13,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.248,-2.832,0.584,,0.689,G,A,0.46,0.99,25.015,25.015,92.05,OHH,-1.646,0.520039,0.00784241,0.976946 beta-lactamase_625_K213C,beta-lactamase_625_213,TEM-1,beta-lactamase_625,P62593,0.976951,NO,213,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.81,-5.208,3.398,,0.67,,A,2.34,0.29,3.924,,67.83,ABH,-1.57767,0.213352,0.00610411,0.976951 beta-lactamase_156_L199V,beta-lactamase_156_199,TEM-1,beta-lactamase_156,P62593,0.976958,NO,199,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-2.942,-2.773,-0.169,,0.832,H,A,0.55,0.42,1.552,,77.62,PHH,-2.32933,0.111618,0.0048649,0.976958 beta-lactamase_625_R81Q,beta-lactamase_625_81,TEM-1,beta-lactamase_625,P62593,0.97696,NO,81,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.466,-2.446,0.98,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.213352,0.00499763,0.97696 beta-lactamase_39_L218V,beta-lactamase_39_218,TEM-1,beta-lactamase_39,P62593,0.976961,NO,218,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.391,-3.3,1.909,,,I,b,0.55,-0.53,2.038,,74.48,OHH,-1.58867,0.0495842,0.00618274,0.976961 beta-lactamase_156_N98M,beta-lactamase_156_98,TEM-1,beta-lactamase_156,P62593,0.976962,NO,98,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-2.973,-4.74,1.767,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.111618,0.00505389,0.976962 beta-lactamase_F17I,beta-lactamase_17,TEM-1,beta-lactamase,P62593,0.976962,NO,17,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-2.337,-2.638,0.301,,,,,,,2.192,,67.83,HHO,-2.17733,0.221079,0.00216499,0.976962 beta-lactamase_L160A,beta-lactamase_160,TEM-1,beta-lactamase,P62593,0.976962,NO,160,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.977,-3.094,2.117,5.32068,0.022,,B,1.75,-0.6,0.895,,44.41,BHA,-0.936,0.221079,0.00193775,0.976962 beta-lactamase_625_R81S,beta-lactamase_625_81,TEM-1,beta-lactamase_625,P62593,0.976963,NO,81,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.466,-3.386,1.92,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.213352,0.00499763,0.976963 beta-lactamase_2500_E279N,beta-lactamase_2500_279,TEM-1,beta-lactamase_2500,P62593,0.976973,NO,279,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.361275,0.0192826,0.976973 beta-lactamase_156_E272P,beta-lactamase_156_272,TEM-1,beta-lactamase_156,P62593,0.976978,NO,272,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.111618,0.00545371,0.976978 kka2_1:1_S251I,kka2_1:1_251,Kka2,kka2_1:1,P00552,0.976981,NO,251,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.636,-4.095,1.459,,0.712,H,A,0.27,-0.25,1.356,,71.59,APP,-2.09367,0.520039,0.0138916,0.976981 kka2_1:8_V186C,kka2_1:8_186,Kka2,kka2_1:8,P00552,0.976984,NO,186,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.011,-4.765,3.754,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.100394,0.00409703,0.976984 kka2_1:8_V186C,kka2_1:8_186,Kka2,kka2_1:8,P00552,0.976984,NO,186,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.011,-4.765,3.754,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.100394,0.00409703,0.976984 beta-lactamase_S96V,beta-lactamase_96,TEM-1,beta-lactamase,P62593,0.976992,NO,96,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.27,-3.642,1.372,5.29889,0.368,,b,0.25,0.39,32.348,32.348,73.78,HPP,-2.019,0.221079,0.00551835,0.976992 beta-lactamase_625_L89T,beta-lactamase_625_89,TEM-1,beta-lactamase_625,P62593,0.977001,NO,89,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.096,-3.474,2.378,,0.168,T,A,0.55,0.63,1.599,,64.34,PHO,-1.75767,0.213352,0.00207068,0.977001 beta-lactamase_156_E62I,beta-lactamase_156_62,TEM-1,beta-lactamase_156,P62593,0.977003,NO,62,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.193,-4.086,2.893,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.111618,0.00264802,0.977003 kka2_1:2_I29M,kka2_1:2_29,Kka2,kka2_1:2,P00552,0.977003,NO,29,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.692,-3.049,1.357,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.295029,0.00619521,0.977003 beta-lactamase_39_K254E,beta-lactamase_39_254,TEM-1,beta-lactamase_39,P62593,0.977007,NO,254,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.0495842,0.00369,0.977007 beta-lactamase_Q203D,beta-lactamase_203,TEM-1,beta-lactamase,P62593,0.977012,NO,203,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.168,-2.512,0.344,5.65296,0.47,H,A,0.12,-0.38,1.66,,65.38,BPP,-1.614,0.221079,0.00631514,0.977012 kka2_1:4_M116Y,kka2_1:4_116,Kka2,kka2_1:4,P00552,0.977018,NO,116,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-2.482,-2.927,0.445,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.168804,0.00745147,0.977018 Pab1_E175I,Pab1_175,Pab1,Pab1,P04147,0.977018,NO,175,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.055,-3.912,1.857,,,,,,,,,,AAA,-1.82667,0.175299,0.00203137,0.977018 kka2_1:8_N195S,kka2_1:8_195,Kka2,kka2_1:8,P00552,0.97702,NO,195,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-0.836,-3.008,2.172,,0.037,G,A,0.43,-1.36,1.108,,48.11,OPH,-1.26567,0.100394,0.00276134,0.97702 kka2_1:8_N195S,kka2_1:8_195,Kka2,kka2_1:8,P00552,0.97702,NO,195,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-0.836,-3.008,2.172,,0.037,G,A,0.43,-1.36,1.108,,48.11,OPH,-1.26567,0.100394,0.00276134,0.97702 beta-lactamase_625_E195V,beta-lactamase_625_195,TEM-1,beta-lactamase_625,P62593,0.977022,NO,195,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.186,-3.798,1.612,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.213352,0.00496565,0.977022 beta-lactamase_0_S51K,beta-lactamase_0_51,TEM-1,beta-lactamase_0,P62593,0.977024,NO,51,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.526,-3.459,1.933,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.0500837,0.00504821,0.977024 beta-lactamase_39_E35R,beta-lactamase_39_35,TEM-1,beta-lactamase_39,P62593,0.97703,NO,35,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-0.869,-3.551,2.682,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.0495842,0.00174441,0.97703 beta-lactamase_156_G226H,beta-lactamase_156_226,TEM-1,beta-lactamase_156,P62593,0.977033,NO,226,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.461,-4.656,3.195,,0.701,T,l,0.29,-0.25,3.199,,74.48,HOH,-1.42933,0.111618,0.00665294,0.977033 beta-lactamase_156_A268L,beta-lactamase_156_268,TEM-1,beta-lactamase_156,P62593,0.977043,NO,268,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.111618,0.0102525,0.977043 beta-lactamase_0_S241L,beta-lactamase_0_241,TEM-1,beta-lactamase_0,P62593,0.97705,NO,241,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.0500837,0.00452736,0.97705 beta-lactamase_156_G114A,beta-lactamase_156_114,TEM-1,beta-lactamase_156,P62593,0.977055,NO,114,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.094,-2.444,1.35,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.111618,0.00224919,0.977055 beta-lactamase_625_Y103V,beta-lactamase_625_103,TEM-1,beta-lactamase_625,P62593,0.977065,NO,103,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-1.33,-3.602,2.272,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.213352,0.00443048,0.977065 beta-lactamase_M268F,beta-lactamase_268,TEM-1,beta-lactamase,P62593,0.977071,NO,268,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-2.023,-1.893,-0.13,5.4797,0.471,H,A,0.09,0.3,1.071,,65.73,PHA,-2.16233,0.221079,0.0102525,0.977071 beta-lactamase_Q204V,beta-lactamase_204,TEM-1,beta-lactamase,P62593,0.977071,NO,204,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-1.382,-3.595,2.213,5.46394,0.204,H,A,0.12,0.09,1.707,,66.08,PPH,-1.49067,0.221079,0.00364106,0.977071 beta-lactamase_156_D33G,beta-lactamase_156_33,TEM-1,beta-lactamase_156,P62593,0.977078,NO,33,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.321,-3.465,1.144,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.111618,0.00435556,0.977078 beta-lactamase_39_T178I,beta-lactamase_39_178,TEM-1,beta-lactamase_39,P62593,0.977101,NO,178,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-0.791,-3.56,2.769,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.0495842,0.000684366,0.977101 beta-lactamase_39_N98G,beta-lactamase_39_98,TEM-1,beta-lactamase_39,P62593,0.977103,NO,98,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-2.973,-3.401,0.428,,0.963,G,A,0.61,1.35,14.853,14.853,77.62,PPA,-2.07867,0.0495842,0.00505389,0.977103 beta-lactamase_156_Q276F,beta-lactamase_156_276,TEM-1,beta-lactamase_156,P62593,0.977105,NO,276,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.111618,0.0191712,0.977105 beta-lactamase_156_G240C,beta-lactamase_156_240,TEM-1,beta-lactamase_156,P62593,0.977111,NO,240,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.111618,0.00591201,0.977111 beta-lactamase_625_K286N,beta-lactamase_625_286,TEM-1,beta-lactamase_625,P62593,0.977111,NO,286,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.213352,,0.977111 beta-lactamase_M66I,beta-lactamase_66,TEM-1,beta-lactamase,P62593,0.977115,NO,66,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.362,-2.521,1.159,5.29561,0.013,,A,1.3,-0.7,1.319,,73.08,OHH,-1.49567,0.221079,0.00412876,0.977115 beta-lactamase_39_L218A,beta-lactamase_39_218,TEM-1,beta-lactamase_39,P62593,0.977125,NO,218,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.391,-3.175,1.784,,,I,b,0.55,-0.53,2.038,,74.48,OHH,-1.58867,0.0495842,0.00618274,0.977125 beta-lactamase_156_P255N,beta-lactamase_156_255,TEM-1,beta-lactamase_156,P62593,0.977132,NO,255,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.111618,0.00499612,0.977132 Pab1_D184A,Pab1_184,Pab1,Pab1,P04147,0.977132,NO,184,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.5,-3.06,1.56,,,,,,,,,,HAH,-1.50133,0.175299,0.0011931,0.977132 beta-lactamase_625_P143H,beta-lactamase_625_143,TEM-1,beta-lactamase_625,P62593,0.977134,NO,143,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.967,-4.789,3.822,,0.075,H,A,0.52,-0.37,1.445,,66.78,OOB,-1.354,0.213352,0.00114551,0.977134 beta-lactamase_39_Y103F,beta-lactamase_39_103,TEM-1,beta-lactamase_39,P62593,0.977143,NO,103,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-1.33,-3.391,2.061,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.0495842,0.00443048,0.977143 beta-lactamase_2500_Q88I,beta-lactamase_2500_88,TEM-1,beta-lactamase_2500,P62593,0.977149,NO,88,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.086,-3.166,1.08,,0.807,,B,0.64,2.03,1.84,,77.62,APH,-1.53433,0.361275,0.00504167,0.977149 beta-lactamase_0_L100C,beta-lactamase_0_100,TEM-1,beta-lactamase_0,P62593,0.977161,NO,100,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.218,-4.758,3.54,,0.343,,B,0.55,0.13,1.373,,63.29,AHH,-1.23467,0.0500837,0.00413885,0.977161 beta-lactamase_156_N168S,beta-lactamase_156_168,TEM-1,beta-lactamase_156,P62593,0.977164,NO,168,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-1.029,-2.37,1.341,,0.113,G,A,0.61,-0.4,1.014,,44.41,HPA,-1.13233,0.111618,0.00288667,0.977164 beta-lactamase_39_A77N,beta-lactamase_39_77,TEM-1,beta-lactamase_39,P62593,0.977165,NO,77,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.234,-3.844,2.61,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.0495842,0.00282362,0.977165 beta-lactamase_625_K254E,beta-lactamase_625_254,TEM-1,beta-lactamase_625,P62593,0.977177,NO,254,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.213352,0.00369,0.977177 beta-lactamase_T158S,beta-lactamase_158,TEM-1,beta-lactamase,P62593,0.977178,NO,158,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.116,-1.795,0.679,5.32011,0.036,,B,0.98,-0.85,2.755,,69.58,HPB,-1.269,0.221079,0.00341825,0.977178 beta-lactamase_156_L100G,beta-lactamase_156_100,TEM-1,beta-lactamase_156,P62593,0.977181,NO,100,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.218,-3.854,2.636,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.111618,0.00413885,0.977181 kka2_1:4_D227N,kka2_1:4_227,Kka2,kka2_1:4,P00552,0.977183,NO,227,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.758,-3.296,1.538,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.168804,0.00745029,0.977183 beta-lactamase_625_D113A,beta-lactamase_625_113,TEM-1,beta-lactamase_625,P62593,0.977198,NO,113,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.829,-2.412,0.583,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.213352,0.00474112,0.977198 beta-lactamase_2500_E175L,beta-lactamase_2500_175,TEM-1,beta-lactamase_2500,P62593,0.977203,NO,175,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.336,-3.444,1.108,,0.551,,A,1.04,1.05,5.316,,77.62,AAB,-1.31233,0.361275,0.00482205,0.977203 kka2_1:4_G210C,kka2_1:4_210,Kka2,kka2_1:4,P00552,0.977204,NO,210,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.095,-2.875,1.78,,0.103,T,A,0.29,-0.62,0.271,,50,OOB,-0.966667,0.168804,0.00598378,0.977204 beta-lactamase_W163L,beta-lactamase_163,TEM-1,beta-lactamase,P62593,0.977205,NO,163,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-1.843,-2.838,0.995,6.2765,0.467,,B,1.22,-0.5,3.642,,63.99,BHA,-1.269,0.221079,0.00418955,0.977205 beta-lactamase_39_D48W,beta-lactamase_39_48,TEM-1,beta-lactamase_39,P62593,0.977206,NO,48,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.101,-5.502,4.401,,0.189,E,B,0.75,0.21,0.735,,50.35,HAH,-1.62467,0.0495842,0.0027273,0.977206 beta-lactamase_2500_A225H,beta-lactamase_2500_225,TEM-1,beta-lactamase_2500,P62593,0.977212,NO,225,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.845,-3.109,1.264,,1,T,B,0.46,-0.38,0.551,,74.48,OHO,-1.39967,0.361275,0.00465057,0.977212 beta-lactamase_39_E175F,beta-lactamase_39_175,TEM-1,beta-lactamase_39,P62593,0.977215,NO,175,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.336,-4.36,2.024,,0.551,,A,1.04,1.05,3.676,,77.62,AAB,-1.31233,0.0495842,0.00482205,0.977215 beta-lactamase_39_P172C,beta-lactamase_39_172,TEM-1,beta-lactamase_39,P62593,0.977219,NO,172,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.998,-4.977,3.979,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.0495842,0.00312594,0.977219 beta-lactamase_39_Q203H,beta-lactamase_39_203,TEM-1,beta-lactamase_39,P62593,0.97722,NO,203,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.168,-4.663,2.495,,0.47,H,A,0.64,-0.38,1.453,,65.38,BPP,-1.614,0.0495842,0.00631514,0.97722 beta-lactamase_E277L,beta-lactamase_277,TEM-1,beta-lactamase,P62593,0.977221,NO,277,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.869,-3.659,1.79,5.51786,0.545,H,A,0.52,-0.01,2.022,,77.62,HAH,-1.45367,0.221079,0.0169305,0.977221 beta-lactamase_L247I,beta-lactamase_247,TEM-1,beta-lactamase,P62593,0.977221,NO,247,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.48,-1.734,0.254,5.28771,0.007,E,B,2.89,-0.72,2.951,,63.99,HHO,-1.79833,0.221079,0.00611275,0.977221 beta-lactamase_625_L188A,beta-lactamase_625_188,TEM-1,beta-lactamase_625,P62593,0.977222,NO,188,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.166,-2.542,1.376,,,H,A,0.55,-0.3,2.982,,60.14,PHB,-1.47033,0.213352,0.00295687,0.977222 beta-lactamase_39_V82H,beta-lactamase_39_82,TEM-1,beta-lactamase_39,P62593,0.977229,NO,82,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.325,-4.872,3.547,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.0495842,0.00397046,0.977229 beta-lactamase_39_K53Q,beta-lactamase_39_53,TEM-1,beta-lactamase_39,P62593,0.977236,NO,53,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-2.313,-2.642,0.329,,0.589,,B,2.34,1.15,15.633,15.633,77.62,OBH,-2.1,0.0495842,0.00383383,0.977236 kka2_1:4_P98T,kka2_1:4_98,Kka2,kka2_1:4,P00552,0.977238,NO,98,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.526,-2.967,1.441,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.168804,0.00622754,0.977238 beta-lactamase_2500_E175V,beta-lactamase_2500_175,TEM-1,beta-lactamase_2500,P62593,0.97724,NO,175,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.336,-2.38,0.044,,0.551,,A,1.04,1.05,5.316,,77.62,AAB,-1.31233,0.361275,0.00482205,0.97724 beta-lactamase_625_L55E,beta-lactamase_625_55,TEM-1,beta-lactamase_625,P62593,0.977248,NO,55,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.86,-3.84,1.98,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.213352,0.00403741,0.977248 kka2_1:8_D156K,kka2_1:8_156,Kka2,kka2_1:8,P00552,0.977249,NO,156,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.696,-3.566,1.87,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.100394,0.00926998,0.977249 kka2_1:8_D156K,kka2_1:8_156,Kka2,kka2_1:8,P00552,0.977249,NO,156,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.696,-3.566,1.87,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.100394,0.00926998,0.977249 kka2_1:2_T73K,kka2_1:2_73,Kka2,kka2_1:2,P00552,0.977256,NO,73,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.51,-2.995,0.485,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.295029,0.00628605,0.977256 beta-lactamase_625_D252N,beta-lactamase_625_252,TEM-1,beta-lactamase_625,P62593,0.977257,NO,252,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.213352,0.00575769,0.977257 PSD95pdz3_D366M,PSD95pdz3_366,PSD95pdz3,PSD95pdz3,P31016,0.977259,NO,366,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.264,-4.612,3.348,5.55684,,,,,20.2375,,,,HAH,-1.401,0.0758425,0.000481272,0.977259 beta-lactamase_39_D113K,beta-lactamase_39_113,TEM-1,beta-lactamase_39,P62593,0.977264,NO,113,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.829,-2.696,0.867,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.0495842,0.00474112,0.977264 beta-lactamase_625_D99F,beta-lactamase_625_99,TEM-1,beta-lactamase_625,P62593,0.977271,NO,99,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.191,-4.277,3.086,,0.402,G,A,0.75,0.36,1.318,,64.69,PAH,-1.794,0.213352,0.00305446,0.977271 beta-lactamase_E237T,beta-lactamase_237,TEM-1,beta-lactamase,P62593,0.977275,NO,237,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.058,-3.593,1.535,5.42877,0.583,S,B,1.62,1.2,2.144,,77.62,OAB,-1.61467,0.221079,0.0048626,0.977275 beta-lactamase_I11F,beta-lactamase_11,TEM-1,beta-lactamase,P62593,0.977275,NO,11,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.745,-2.161,0.416,,,,,,,3.135,,66.08,HHO,-1.79467,0.221079,0.00261325,0.977275 kka2_1:1_K50R,kka2_1:1_50,Kka2,kka2_1:1,P00552,0.977282,NO,50,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-0.833,-2.445,1.612,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.520039,0.00138626,0.977282 kka2_1:4_L165P,kka2_1:4_165,Kka2,kka2_1:4,P00552,0.977283,NO,165,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-2.453,-3.229,0.776,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.168804,0.00801161,0.977283 beta-lactamase_625_M127A,beta-lactamase_625_127,TEM-1,beta-lactamase_625,P62593,0.977288,NO,127,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-2.251,-3.303,1.052,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.213352,0.00437927,0.977288 beta-lactamase_2500_T264S,beta-lactamase_2500_264,TEM-1,beta-lactamase_2500,P62593,0.977292,NO,264,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.985,-1.764,-0.221,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.361275,0.0119399,0.977292 beta-lactamase_156_A185T,beta-lactamase_156_185,TEM-1,beta-lactamase_156,P62593,0.977294,NO,185,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.406,-2.128,0.722,,,H,A,0.46,-1.02,0.365,,65.03,HHP,-1.84033,0.111618,0.00467449,0.977294 beta-lactamase_39_M115F,beta-lactamase_39_115,TEM-1,beta-lactamase_39,P62593,0.977296,NO,115,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.389,-2.82,1.431,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.0495842,0.0034337,0.977296 beta-lactamase_2500_S256D,beta-lactamase_2500_256,TEM-1,beta-lactamase_2500,P62593,0.977297,NO,256,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.361275,0.00710634,0.977297 Pab1_N192G,Pab1_192,Pab1,Pab1,P04147,0.977301,NO,192,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-1.079,-2.725,1.646,,0.619,T,l,,2.28,,,,HPO,-1.231,0.175299,0.000273498,0.977301 beta-lactamase_E166T,beta-lactamase_166,TEM-1,beta-lactamase,P62593,0.977307,NO,166,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.756,-2.857,1.101,5.60527,0.508,G,A,0.52,1.05,2.124,,73.08,OAH,-1.42233,0.221079,0.00512989,0.977307 beta-lactamase_2500_G85N,beta-lactamase_2500_85,TEM-1,beta-lactamase_2500,P62593,0.977308,NO,85,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.011,-3.501,2.49,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.361275,0.00252173,0.977308 beta-lactamase_39_H156I,beta-lactamase_39_156,TEM-1,beta-lactamase_39,P62593,0.977312,NO,156,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-3.156,-4.08,0.924,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.0495842,0.00468596,0.977312 beta-lactamase_2500_I244L,beta-lactamase_2500_244,TEM-1,beta-lactamase_2500,P62593,0.977318,NO,244,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.555,-2.697,1.142,,,E,B,0.48,-0.84,1.683,,77.62,OHH,-1.385,0.361275,0.00605379,0.977318 beta-lactamase_625_E62L,beta-lactamase_625_62,TEM-1,beta-lactamase_625,P62593,0.977336,NO,62,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.193,-3.66,2.467,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.213352,0.00264802,0.977336 beta-lactamase_625_P105S,beta-lactamase_625_105,TEM-1,beta-lactamase_625,P62593,0.977336,NO,105,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.813,-2.526,1.713,,0.226,T,A,0.52,0.8,1.154,,63.29,POH,-1.01533,0.213352,0.0011981,0.977336 beta-lactamase_39_R189Y,beta-lactamase_39_189,TEM-1,beta-lactamase_39,P62593,0.977342,NO,189,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.844,-3.134,1.29,,0.278,H,A,1.2,1.01,12.11,12.11,72.73,HBB,-1.668,0.0495842,0.0050699,0.977342 beta-lactamase_39_D48E,beta-lactamase_39_48,TEM-1,beta-lactamase_39,P62593,0.977343,NO,48,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.101,-2.049,0.948,,0.189,E,B,0.75,0.21,0.735,,50.35,HAH,-1.62467,0.0495842,0.0027273,0.977343 beta-lactamase_625_I171H,beta-lactamase_625_171,TEM-1,beta-lactamase_625,P62593,0.977343,NO,171,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-2.431,-4.817,2.386,,0.361,,B,0.48,0.53,3.869,,77.62,HHO,-1.55533,0.213352,0.00623355,0.977343 beta-lactamase_39_E102W,beta-lactamase_39_102,TEM-1,beta-lactamase_39,P62593,0.977349,NO,102,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.118,-5.479,3.361,,0.722,S,B,1.04,1.82,3.87,,73.08,HAH,-1.581,0.0495842,0.00486633,0.977349 Pab1_K180S,Pab1_180,Pab1,Pab1,P04147,0.977355,NO,180,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.945,-2.56,0.615,,,,,,,,,,HBA,-1.575,0.175299,0.00295933,0.977355 beta-lactamase_2500_D99Q,beta-lactamase_2500_99,TEM-1,beta-lactamase_2500,P62593,0.977356,NO,99,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.191,-2.836,1.645,,0.402,G,A,0.75,0.36,1.318,,64.69,PAH,-1.794,0.361275,0.00305446,0.977356 beta-lactamase_39_T193W,beta-lactamase_39_193,TEM-1,beta-lactamase_39,P62593,0.977366,NO,193,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.914,-5.211,3.297,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.0495842,0.00482669,0.977366 Pab1_A179F,Pab1_179,Pab1,Pab1,P04147,0.977369,NO,179,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.013,-3.884,2.871,,0.078,H,A,0.61,0.5,,,,HHB,-1.51233,0.175299,0.000291703,0.977369 beta-lactamase_2500_K144M,beta-lactamase_2500_144,TEM-1,beta-lactamase_2500,P62593,0.977378,NO,144,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-2.388,-4.736,2.348,,0.863,H,A,2.34,1.27,0.515,,77.62,OBA,-1.904,0.361275,0.00481141,0.977378 beta-lactamase_625_D252T,beta-lactamase_625_252,TEM-1,beta-lactamase_625,P62593,0.977378,NO,252,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.213352,0.00575769,0.977378 beta-lactamase_2500_E175Q,beta-lactamase_2500_175,TEM-1,beta-lactamase_2500,P62593,0.977382,NO,175,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.336,-3.092,0.756,,0.551,,A,1.04,1.05,5.316,,77.62,AAB,-1.31233,0.361275,0.00482205,0.977382 beta-lactamase_39_L100N,beta-lactamase_39_100,TEM-1,beta-lactamase_39,P62593,0.977394,NO,100,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.218,-4.207,2.989,,0.343,,B,0.55,0.13,8.311,,63.29,AHH,-1.23467,0.0495842,0.00413885,0.977394 gb1_T270Y,gb1_270,gb1,gb1,P06654,0.977406,NO,270,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-3.15,-3.536,0.386,,,,,,,1.326,,45.54,HPH,-1.843,0.177985,0.00223707,0.977406 beta-lactamase_625_G114S,beta-lactamase_625_114,TEM-1,beta-lactamase_625,P62593,0.977407,NO,114,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.094,-2.588,1.494,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.213352,0.00224919,0.977407 beta-lactamase_39_L192W,beta-lactamase_39_192,TEM-1,beta-lactamase_39,P62593,0.977409,NO,192,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.254,-5.176,3.922,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.0495842,0.00558728,0.977409 kka2_1:8_H162V,kka2_1:8_162,Kka2,kka2_1:8,P00552,0.977425,NO,162,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-2.319,-3.881,1.562,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.100394,0.00616145,0.977425 kka2_1:8_H162V,kka2_1:8_162,Kka2,kka2_1:8,P00552,0.977425,NO,162,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-2.319,-3.881,1.562,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.100394,0.00616145,0.977425 beta-lactamase_2500_E195N,beta-lactamase_2500_195,TEM-1,beta-lactamase_2500,P62593,0.977433,NO,195,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.186,-2.977,0.791,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.361275,0.00496565,0.977433 beta-lactamase_2500_H287W,beta-lactamase_2500_287,TEM-1,beta-lactamase_2500,P62593,0.977439,NO,287,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,,,,,,,,,,,,,BBH,-1.111,0.361275,,0.977439 beta-lactamase_A182Q,beta-lactamase_182,TEM-1,beta-lactamase,P62593,0.977441,NO,182,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.777,-3.097,1.32,4.98609,0.136,H,A,0.52,-0.66,2.032,,93.01,OHH,-1.27367,0.221079,0.00559099,0.977441 beta-lactamase_A280W,beta-lactamase_280,TEM-1,beta-lactamase,P62593,0.977441,NO,280,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.708,-3.245,1.537,4.74932,0.379,H,A,0.52,-0.72,1.785,,68.18,OHP,-1.66433,0.221079,0.0530888,0.977441 beta-lactamase_A77L,beta-lactamase_77,TEM-1,beta-lactamase,P62593,0.977441,NO,77,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.234,-2.423,1.189,4.75777,0.039,H,A,0.52,-0.56,1.708,,64.34,OHH,-1.294,0.221079,0.00282362,0.977441 beta-lactamase_A84I,beta-lactamase_84,TEM-1,beta-lactamase,P62593,0.977441,NO,84,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.651,-3.932,2.281,5.28927,0.65,T,A,0.52,0.96,1.863,,68.18,AHO,-1.24267,0.221079,0.00503822,0.977441 beta-lactamase_H156V,beta-lactamase_156,TEM-1,beta-lactamase,P62593,0.977441,NO,156,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-3.156,-3.735,0.579,6.00284,0.753,S,A,0.72,-0.6,6.456,6.456,77.62,ABH,-1.932,0.221079,0.00468596,0.977441 beta-lactamase_L199S,beta-lactamase_199,TEM-1,beta-lactamase,P62593,0.977441,NO,199,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-2.942,-2.568,-0.374,5.57712,0.832,H,A,0.82,0.42,15.302,15.302,77.62,PHH,-2.32933,0.221079,0.0048649,0.977441 beta-lactamase_T193F,beta-lactamase_193,TEM-1,beta-lactamase,P62593,0.977441,NO,193,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.914,-2.368,0.454,5.67952,0.439,H,a,0.3,0.33,1.863,,63.99,HPO,-1.52133,0.221079,0.00482669,0.977441 beta-lactamase_156_L49K,beta-lactamase_156_49,TEM-1,beta-lactamase_156,P62593,0.977442,NO,49,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.897,-3.583,1.686,,0.131,T,A,0.55,0.04,3.112,,64.69,AHP,-1.99233,0.111618,0.00401477,0.977442 kka2_1:8_L184V,kka2_1:8_184,Kka2,kka2_1:8,P00552,0.977442,NO,184,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.496,-2.642,1.146,,0.489,E,B,0.55,-0.06,4.495,,63.26,AHH,-1.24833,0.100394,0.00518742,0.977442 kka2_1:8_L184V,kka2_1:8_184,Kka2,kka2_1:8,P00552,0.977442,NO,184,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.496,-2.642,1.146,,0.489,E,B,0.55,-0.06,4.495,,63.26,AHH,-1.24833,0.100394,0.00518742,0.977442 beta-lactamase_156_T139V,beta-lactamase_156_139,TEM-1,beta-lactamase_156,P62593,0.977448,NO,139,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.901,-3.468,1.567,,0.216,H,A,0.22,0.39,16.34,16.34,77.62,PPH,-2.04667,0.111618,0.00441837,0.977448 beta-lactamase_625_D48A,beta-lactamase_625_48,TEM-1,beta-lactamase_625,P62593,0.977464,NO,48,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.101,-2.565,1.464,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.213352,0.0027273,0.977464 beta-lactamase_156_T147H,beta-lactamase_156_147,TEM-1,beta-lactamase_156,P62593,0.977477,NO,147,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.149,-4.643,3.494,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.111618,0.00226017,0.977477 beta-lactamase_625_D252F,beta-lactamase_625_252,TEM-1,beta-lactamase_625,P62593,0.977481,NO,252,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.213352,0.00575769,0.977481 beta-lactamase_39_S266P,beta-lactamase_39_266,TEM-1,beta-lactamase_39,P62593,0.977482,NO,266,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.0495842,0.0140785,0.977482 beta-lactamase_0_D83N,beta-lactamase_0_83,TEM-1,beta-lactamase_0,P62593,0.977487,NO,83,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.066,-3.355,2.289,,0.354,H,A,0.75,0.22,0.617,,48.95,HAH,-1.34733,0.0500837,0.00205968,0.977487 beta-lactamase_2500_I171H,beta-lactamase_2500_171,TEM-1,beta-lactamase_2500,P62593,0.977487,NO,171,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-2.431,-4.817,2.386,,0.361,,B,0.48,0.53,1.66,,77.62,HHO,-1.55533,0.361275,0.00623355,0.977487 beta-lactamase_0_Y103G,beta-lactamase_0_103,TEM-1,beta-lactamase_0,P62593,0.9775,NO,103,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-1.33,-3.527,2.197,,0.613,S,l,0.21,1.21,1.646,,63.29,AHP,-1.48767,0.0500837,0.00443048,0.9775 beta-lactamase_2500_L49W,beta-lactamase_2500_49,TEM-1,beta-lactamase_2500,P62593,0.977505,NO,49,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.897,-5.315,3.418,,0.131,T,A,0.55,0.04,6.681,,64.69,AHP,-1.99233,0.361275,0.00401477,0.977505 beta-lactamase_2500_K32L,beta-lactamase_2500_32,TEM-1,beta-lactamase_2500,P62593,0.977511,NO,32,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.984,-2.812,0.828,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.361275,0.00401283,0.977511 kka2_1:2_A168D,kka2_1:2_168,Kka2,kka2_1:2,P00552,0.977542,NO,168,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.989,-2.545,0.556,,0.67,H,A,0.46,0.15,25.546,25.546,64.39,OHA,-2.12933,0.295029,0.00806773,0.977542 beta-lactamase_39_S221W,beta-lactamase_39_221,TEM-1,beta-lactamase_39,P62593,0.977553,NO,221,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.754,-5.418,3.664,,0.624,H,A,0.27,-0.2,2.69,,74.48,BPH,-1.59967,0.0495842,0.0046094,0.977553 beta-lactamase_2500_D271H,beta-lactamase_2500_271,TEM-1,beta-lactamase_2500,P62593,0.977562,NO,271,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.361275,0.00752082,0.977562 beta-lactamase_625_S104H,beta-lactamase_625_104,TEM-1,beta-lactamase_625,P62593,0.977565,NO,104,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.015,-4.582,3.567,,0.04,,b,0.27,0.57,1.76,,63.29,HPO,-1.05267,0.213352,0.00218083,0.977565 beta-lactamase_156_G90T,beta-lactamase_156_90,TEM-1,beta-lactamase_156,P62593,0.977569,NO,90,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-2.091,-2.913,0.822,,0.598,T,A,0.29,0.32,0.319,,77.62,HOB,-1.52633,0.111618,0.00490273,0.977569 beta-lactamase_156_L199K,beta-lactamase_156_199,TEM-1,beta-lactamase_156,P62593,0.977569,NO,199,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-2.942,-2.994,0.052,,0.832,H,A,0.55,0.42,1.552,,77.62,PHH,-2.32933,0.111618,0.0048649,0.977569 beta-lactamase_2500_E26D,beta-lactamase_2500_26,TEM-1,beta-lactamase_2500,P62593,0.977571,NO,26,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.454,-2.507,0.053,,0.54,H,A,1.04,0.98,0.49,,93.01,OAP,-1.96167,0.361275,0.00297948,0.977571 beta-lactamase_L79M,beta-lactamase_79,TEM-1,beta-lactamase,P62593,0.977579,NO,79,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.842,-2.761,1.919,4.98681,0.007,H,A,1.07,-0.16,0.823,,50.35,HHP,-1.44333,0.221079,0.000947397,0.977579 beta-lactamase_W163E,beta-lactamase_163,TEM-1,beta-lactamase,P62593,0.977579,NO,163,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-1.843,-3.693,1.85,6.2765,0.467,,B,1.22,-0.5,3.642,,63.99,BHA,-1.269,0.221079,0.00418955,0.977579 Pab1_E195L,Pab1_195,Pab1,Pab1,P04147,0.977583,NO,195,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.2,-3.394,2.194,,,,,,,,,,PAH,-1.72467,0.175299,0.000620107,0.977583 Pab1_N132H,Pab1_132,Pab1,Pab1,P04147,0.977584,NO,132,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-1.079,-3.822,2.743,,0.412,S,l,,0.9,,,,BPH,-1.067,0.175299,0.000347671,0.977584 beta-lactamase_156_S266N,beta-lactamase_156_266,TEM-1,beta-lactamase_156,P62593,0.977586,NO,266,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.111618,0.0140785,0.977586 beta-lactamase_156_S96F,beta-lactamase_156_96,TEM-1,beta-lactamase_156,P62593,0.977594,NO,96,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.27,-4.388,2.118,,0.368,,b,0.27,0.39,2.838,,73.78,HPP,-2.019,0.111618,0.00551835,0.977594 beta-lactamase_625_D33W,beta-lactamase_625_33,TEM-1,beta-lactamase_625,P62593,0.977606,NO,33,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.321,-5.495,3.174,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.213352,0.00435556,0.977606 beta-lactamase_625_L192C,beta-lactamase_625_192,TEM-1,beta-lactamase_625,P62593,0.977615,NO,192,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.254,-4.743,3.489,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.213352,0.00558728,0.977615 beta-lactamase_0_L284A,beta-lactamase_0_284,TEM-1,beta-lactamase_0,P62593,0.977619,NO,284,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.981,,,,0.848,H,A,2.89,0.67,4.544,,77.62,PHH,-1.82133,0.0500837,0.0686156,0.977619 beta-lactamase_2500_E169N,beta-lactamase_2500_169,TEM-1,beta-lactamase_2500,P62593,0.977623,NO,169,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.23,-3.55,2.32,,0.337,,A,1.04,1,1.806,,73.08,PAH,-1.16533,0.361275,0.00400994,0.977623 beta-lactamase_156_T147K,beta-lactamase_156_147,TEM-1,beta-lactamase_156,P62593,0.977624,NO,147,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.149,-3.536,2.387,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.111618,0.00226017,0.977624 beta-lactamase_39_R81V,beta-lactamase_39_81,TEM-1,beta-lactamase_39,P62593,0.977631,NO,81,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.466,-3.685,2.219,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.0495842,0.00499763,0.977631 beta-lactamase_625_V157Q,beta-lactamase_625_157,TEM-1,beta-lactamase_625,P62593,0.977637,NO,157,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.751,-4.045,2.294,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.213352,0.00506849,0.977637 beta-lactamase_156_S266E,beta-lactamase_156_266,TEM-1,beta-lactamase_156,P62593,0.977638,NO,266,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.111618,0.0140785,0.977638 beta-lactamase_39_S96F,beta-lactamase_39_96,TEM-1,beta-lactamase_39,P62593,0.977641,NO,96,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.27,-4.388,2.118,,0.368,,b,0.27,0.39,2.516,,73.78,HPP,-2.019,0.0495842,0.00551835,0.977641 beta-lactamase_156_L188A,beta-lactamase_156_188,TEM-1,beta-lactamase_156,P62593,0.977661,NO,188,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.166,-2.542,1.376,,,H,A,0.55,-0.3,1.574,,60.14,PHB,-1.47033,0.111618,0.00295687,0.977661 beta-lactamase_39_V78K,beta-lactamase_39_78,TEM-1,beta-lactamase_39,P62593,0.977672,NO,78,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.459,-3.849,2.39,,,H,A,0.44,-0.47,1.132,,63.64,HHH,-1.17833,0.0495842,0.00492501,0.977672 beta-lactamase_A170F,beta-lactamase_170,TEM-1,beta-lactamase,P62593,0.977673,NO,170,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.237,-2.633,1.396,5.19261,0.126,,L,2.34,-0.35,2.427,,64.69,AHH,-1.63267,0.221079,0.00431903,0.977673 beta-lactamase_A280L,beta-lactamase_280,TEM-1,beta-lactamase,P62593,0.977673,NO,280,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.708,-3.493,1.785,4.74932,0.379,H,A,0.52,-0.72,1.785,,68.18,OHP,-1.66433,0.221079,0.0530888,0.977673 beta-lactamase_39_D271Q,beta-lactamase_39_271,TEM-1,beta-lactamase_39,P62593,0.977675,NO,271,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.0495842,0.00752082,0.977675 beta-lactamase_625_R92D,beta-lactamase_625_92,TEM-1,beta-lactamase_625,P62593,0.977677,NO,92,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.718,-3.708,1.99,,0.479,E,B,1.2,1.36,3.069,,65.38,BBH,-1.50367,0.213352,0.00429626,0.977677 beta-lactamase_39_N98Y,beta-lactamase_39_98,TEM-1,beta-lactamase_39,P62593,0.977679,NO,98,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-2.973,-4.22,1.247,,0.963,G,A,0.61,1.35,14.853,14.853,77.62,PPA,-2.07867,0.0495842,0.00505389,0.977679 beta-lactamase_T198A,beta-lactamase_198,TEM-1,beta-lactamase,P62593,0.977699,NO,198,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.168,-2.502,0.334,4.9209,0.489,,B,0.69,-0.13,0.37,,73.78,HPH,-1.98767,0.221079,0.004311,0.977699 beta-lactamase_625_T139A,beta-lactamase_625_139,TEM-1,beta-lactamase_625,P62593,0.977704,NO,139,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.901,-2.031,0.13,,0.216,H,A,0.22,0.39,2.256,,77.62,PPH,-2.04667,0.213352,0.00441837,0.977704 beta-lactamase_2500_Q97F,beta-lactamase_2500_97,TEM-1,beta-lactamase_2500,P62593,0.977718,NO,97,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.072,-4.44,2.368,,0.823,G,A,0.64,2.42,1.157,,77.62,PPP,-2.43833,0.361275,0.0045116,0.977718 beta-lactamase_0_T193K,beta-lactamase_0_193,TEM-1,beta-lactamase_0,P62593,0.977721,NO,193,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.914,-3.726,1.812,,0.439,H,a,0.22,0.33,11.546,11.546,63.99,HPO,-1.52133,0.0500837,0.00482669,0.977721 beta-lactamase_39_E61T,beta-lactamase_39_61,TEM-1,beta-lactamase_39,P62593,0.977722,NO,61,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.115,-3.52,1.405,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.0495842,0.00440955,0.977722 beta-lactamase_I125M,beta-lactamase_125,TEM-1,beta-lactamase,P62593,0.977722,NO,125,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.441,-2.597,1.156,5.23481,,H,A,2.82,-0.7,2.301,,63.29,HHP,-1.248,0.221079,0.00383964,0.977722 PSD95pdz3_Q384H,PSD95pdz3_384,PSD95pdz3,PSD95pdz3,P31016,0.977729,NO,384,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-1.699,-3.912,2.213,5.49339,,,,,23.54,,,,OPP,-1.41333,0.0758425,0.000216736,0.977729 beta-lactamase_39_Q37M,beta-lactamase_39_37,TEM-1,beta-lactamase_39,P62593,0.977731,NO,37,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.134,-4.645,2.511,,0.613,H,A,0.64,1.98,22.282,22.282,73.08,APH,-2.06967,0.0495842,0.00425833,0.977731 beta-lactamase_156_T116R,beta-lactamase_156_116,TEM-1,beta-lactamase_156,P62593,0.977734,NO,116,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.28,-2.627,1.347,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.111618,0.00336175,0.977734 Pab1_I183L,Pab1_183,Pab1,Pab1,P04147,0.977738,NO,183,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.302,-2.379,1.077,,0.308,T,B,1,1.08,1.29,,75.56,HHA,-1.27167,0.175299,0.000574345,0.977738 kka2_1:8_A41R,kka2_1:8_41,Kka2,kka2_1:8,P00552,0.977741,NO,41,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.879,-2.71,0.831,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.100394,0.00543332,0.977741 kka2_1:8_A41R,kka2_1:8_41,Kka2,kka2_1:8,P00552,0.977741,NO,41,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.879,-2.71,0.831,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.100394,0.00543332,0.977741 beta-lactamase_39_E35V,beta-lactamase_39_35,TEM-1,beta-lactamase_39,P62593,0.97775,NO,35,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-0.869,-3.578,2.709,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.0495842,0.00174441,0.97775 beta-lactamase_625_K254W,beta-lactamase_625_254,TEM-1,beta-lactamase_625,P62593,0.97776,NO,254,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.213352,0.00369,0.97776 beta-lactamase_2500_L191I,beta-lactamase_2500_191,TEM-1,beta-lactamase_2500,P62593,0.977767,NO,191,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.087,-3.028,1.941,,,H,A,0.55,0.09,1.703,,63.29,BHH,-1.445,0.361275,0.00263549,0.977767 kka2_1:2_R177R,kka2_1:2_177,Kka2,kka2_1:2,P00552,0.977775,NO,177,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.282,-2.282,,,0.521,T,A,1.2,0.16,1.842,,63.64,HBH,-2.36967,0.295029,0.00768224,0.977775 beta-lactamase_156_T263W,beta-lactamase_156_263,TEM-1,beta-lactamase_156,P62593,0.977788,NO,263,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.111618,0.0110582,0.977788 beta-lactamase_Q88V,beta-lactamase_88,TEM-1,beta-lactamase,P62593,0.977795,NO,88,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.086,-3.621,1.535,5.8056,0.807,,B,0.12,2.03,1.84,,77.62,APH,-1.53433,0.221079,0.00504167,0.977795 beta-lactamase_S96K,beta-lactamase_96,TEM-1,beta-lactamase,P62593,0.977795,NO,96,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.27,-2.895,0.625,5.29889,0.368,,b,0.25,0.39,32.348,32.348,73.78,HPP,-2.019,0.221079,0.00551835,0.977795 beta-lactamase_T187N,beta-lactamase_187,TEM-1,beta-lactamase,P62593,0.977795,NO,187,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.401,-2.373,0.972,5.11453,0.007,H,A,0.3,-1.19,1.751,,67.48,PPH,-1.69633,0.221079,0.00491782,0.977795 Pab1_D144I,Pab1_144,Pab1,Pab1,P04147,0.977804,NO,144,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.189,-3.903,2.714,,0.616,H,A,,0.6,,,,HAP,-1.40567,0.175299,0.00121131,0.977804 beta-lactamase_2500_D271Q,beta-lactamase_2500_271,TEM-1,beta-lactamase_2500,P62593,0.97781,NO,271,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.361275,0.00752082,0.97781 beta-lactamase_0_H24W,beta-lactamase_0_24,TEM-1,beta-lactamase_0,P62593,0.977819,NO,24,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-2.481,-5.305,2.824,,,,,,,2.708,,93.01,OBO,-2.0035,0.0500837,0.00238894,0.977819 beta-lactamase_625_K213L,beta-lactamase_625_213,TEM-1,beta-lactamase_625,P62593,0.97782,NO,213,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.81,-3.558,1.748,,0.67,,A,2.34,0.29,3.924,,67.83,ABH,-1.57767,0.213352,0.00610411,0.97782 beta-lactamase_625_D252P,beta-lactamase_625_252,TEM-1,beta-lactamase_625,P62593,0.977825,NO,252,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.213352,0.00575769,0.977825 beta-lactamase_39_N50F,beta-lactamase_39_50,TEM-1,beta-lactamase_39,P62593,0.977826,NO,50,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-2.979,-4.333,1.354,,0.912,T,A,0.61,1.24,10.736,,77.62,HPP,-2.134,0.0495842,0.0047211,0.977826 beta-lactamase_2500_A225R,beta-lactamase_2500_225,TEM-1,beta-lactamase_2500,P62593,0.977831,NO,225,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.845,-2.864,1.019,,1,T,B,0.46,-0.38,0.551,,74.48,OHO,-1.39967,0.361275,0.00465057,0.977831 beta-lactamase_39_L199D,beta-lactamase_39_199,TEM-1,beta-lactamase_39,P62593,0.977833,NO,199,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-2.942,-3.009,0.067,,0.832,H,A,0.55,0.42,15.504,15.504,77.62,PHH,-2.32933,0.0495842,0.0048649,0.977833 beta-lactamase_2500_S256V,beta-lactamase_2500_256,TEM-1,beta-lactamase_2500,P62593,0.97784,NO,256,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.361275,0.00710634,0.97784 beta-lactamase_39_D36W,beta-lactamase_39_36,TEM-1,beta-lactamase_39,P62593,0.977841,NO,36,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.732,-5.422,2.69,,0.555,H,A,0.75,1.17,13.689,13.689,77.62,AAP,-1.91167,0.0495842,0.00476483,0.977841 beta-lactamase_0_G265S,beta-lactamase_0_265,TEM-1,beta-lactamase_0,P62593,0.977844,NO,265,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.0500837,0.00811926,0.977844 beta-lactamase_156_R81V,beta-lactamase_156_81,TEM-1,beta-lactamase_156,P62593,0.977849,NO,81,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.466,-3.685,2.219,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.111618,0.00499763,0.977849 beta-lactamase_0_G85K,beta-lactamase_0_85,TEM-1,beta-lactamase_0,P62593,0.97785,NO,85,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.011,-2.219,1.208,,0.805,T,l,0.29,1.7,2.25,,63.64,HOP,-1.68733,0.0500837,0.00252173,0.97785 beta-lactamase_156_K254P,beta-lactamase_156_254,TEM-1,beta-lactamase_156,P62593,0.97785,NO,254,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.111618,0.00369,0.97785 E1_Ubiquitin_A46T,E1_Ubiquitin_46,Uba1,E1_Ubiquitin,P0CG63,0.977896,NO,46,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.367,-3.198,1.831,,0.398,T,L,,-0.8,,,,HHO,-1.17167,0.18783,0.004233,0.977896 E1_Ubiquitin_H70W,E1_Ubiquitin_70,Uba1,E1_Ubiquitin,P0CG63,0.977896,NO,70,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-1.36,,,,0.05,E,B,0.61,-0.97,,,93.18,HBH,-1.146,0.18783,0.00206914,0.977896 E1_Ubiquitin_I44W,E1_Ubiquitin_44,Uba1,E1_Ubiquitin,P0CG63,0.977896,NO,44,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.432,-5.187,3.755,,,E,B,0.27,-1.17,4.57,,78.74,HHH,-1.25633,0.18783,0.00209731,0.977896 E1_Ubiquitin_R42F,E1_Ubiquitin_42,Uba1,E1_Ubiquitin,P0CG63,0.977896,NO,42,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.302,-4.162,2.86,,0.244,E,B,,-0.54,,,,PBH,-1.24667,0.18783,0.00224033,0.977896 E1_Ubiquitin_R74Y,E1_Ubiquitin_74,Uba1,E1_Ubiquitin,P0CG63,0.977896,NO,74,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.302,-4.033,2.731,,0.838,T,A,,3.15,,,,HBO,-1.11333,0.18783,0.00180798,0.977896 beta-lactamase_39_L219S,beta-lactamase_39_219,TEM-1,beta-lactamase_39,P62593,0.977898,NO,219,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.313,-3.686,2.373,,,I,A,0.55,-0.51,19.842,19.842,74.48,HHB,-1.21533,0.0495842,0.00664345,0.977898 beta-lactamase_39_V31F,beta-lactamase_39_31,TEM-1,beta-lactamase_39,P62593,0.977899,NO,31,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.822,-2.736,0.914,,,H,A,0.44,-0.46,2.885,,73.78,BHB,-2.03767,0.0495842,0.00478065,0.977899 hsp90_E590W,hsp90_590,hsp90,hsp90,P02829,0.977899,NO,590,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.818,-4.251,0,4.65049,0.021,H,A,,0.03,,,,HAO,-3.338,0.368192,0.000222939,0.977899 beta-lactamase_625_L38W,beta-lactamase_625_38,TEM-1,beta-lactamase_625,P62593,0.9779,NO,38,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.343,-5.229,3.886,,0.088,H,A,0.55,0.2,1.986,,64.34,PHO,-1.78033,0.213352,0.00373244,0.9779 beta-lactamase_156_E46T,beta-lactamase_156_46,TEM-1,beta-lactamase_156,P62593,0.977902,NO,46,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.94,-3.517,1.577,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.111618,0.00427568,0.977902 Pab1_M189I,Pab1_189,Pab1,Pab1,P04147,0.977903,NO,189,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.406,-2.927,1.521,,0.631,E,b,,2.81,,,,OHH,-1.18,0.175299,0.000278756,0.977903 beta-lactamase_39_D161I,beta-lactamase_39_161,TEM-1,beta-lactamase_39,P62593,0.977905,NO,161,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.891,-4.034,3.143,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.0495842,0.000897697,0.977905 beta-lactamase_E108K,beta-lactamase_108,TEM-1,beta-lactamase,P62593,0.97792,NO,108,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.46,-2.182,0.722,5.52079,0.572,G,A,0.52,1.87,1.973,,72.73,PAB,-1.437,0.221079,0.00413372,0.97792 beta-lactamase_E169N,beta-lactamase_169,TEM-1,beta-lactamase,P62593,0.97792,NO,169,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.23,-3.55,2.32,5.78896,0.337,,A,0.52,1,1.806,,73.08,PAH,-1.16533,0.221079,0.00400994,0.97792 beta-lactamase_0_E102L,beta-lactamase_0_102,TEM-1,beta-lactamase_0,P62593,0.97793,NO,102,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.118,-3.618,1.5,,0.722,S,B,1.04,1.82,4.773,,73.08,HAH,-1.581,0.0500837,0.00486633,0.97793 beta-lactamase_625_R176T,beta-lactamase_625_176,TEM-1,beta-lactamase_625,P62593,0.977935,NO,176,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-0.863,-3.421,2.558,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.213352,0.00105554,0.977935 beta-lactamase_E169R,beta-lactamase_169,TEM-1,beta-lactamase,P62593,0.977936,NO,169,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.23,-3.638,2.408,5.78896,0.337,,A,0.52,1,1.806,,73.08,PAH,-1.16533,0.221079,0.00400994,0.977936 beta-lactamase_156_D161A,beta-lactamase_156_161,TEM-1,beta-lactamase_156,P62593,0.977937,NO,161,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.891,-3.235,2.344,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.111618,0.000897697,0.977937 beta-lactamase_156_M67Q,beta-lactamase_156_67,TEM-1,beta-lactamase_156,P62593,0.977937,NO,67,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-2.231,-4.09,1.859,,0.006,G,P,0.55,-0.81,1.463,,65.03,HHP,-1.502,0.111618,0.00409753,0.977937 beta-lactamase_0_H94C,beta-lactamase_0_94,TEM-1,beta-lactamase_0,P62593,0.97794,NO,94,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-2.5,-5.143,2.643,,0.776,,B,0.17,1.24,1.176,,77.62,HBH,-1.872,0.0500837,0.00389226,0.97794 beta-lactamase_156_P255K,beta-lactamase_156_255,TEM-1,beta-lactamase_156,P62593,0.977943,NO,255,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.111618,0.00499612,0.977943 beta-lactamase_2500_K286N,beta-lactamase_2500_286,TEM-1,beta-lactamase_2500,P62593,0.977943,NO,286,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.361275,,0.977943 beta-lactamase_2500_K144T,beta-lactamase_2500_144,TEM-1,beta-lactamase_2500,P62593,0.977944,NO,144,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-2.388,-2.935,0.547,,0.863,H,A,2.34,1.27,0.515,,77.62,OBA,-1.904,0.361275,0.00481141,0.977944 beta-lactamase_625_Q86C,beta-lactamase_625_86,TEM-1,beta-lactamase_625,P62593,0.977947,NO,86,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.4,-5.132,2.732,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.213352,0.00450027,0.977947 beta-lactamase_2500_E61V,beta-lactamase_2500_61,TEM-1,beta-lactamase_2500,P62593,0.977952,NO,61,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.115,-3.784,1.669,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.361275,0.00440955,0.977952 beta-lactamase_625_D33R,beta-lactamase_625_33,TEM-1,beta-lactamase_625,P62593,0.977953,NO,33,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.321,-2.617,0.296,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.213352,0.00435556,0.977953 hsp90_W585F,hsp90_585,hsp90,hsp90,P02829,0.97796,NO,585,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-4.251,-3.22,0,5.31455,0.508,,B,1.22,0.43,,,,OHP,-3.17533,0.368192,0.000222939,0.97796 PSD95pdz3_E331Q,PSD95pdz3_331,PSD95pdz3,PSD95pdz3,P31016,0.977964,NO,331,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.404,-2.906,1.502,5.86289,,,,,51.8889,,,,OAA,-1.22533,0.0758425,0.000950134,0.977964 beta-lactamase_156_H151C,beta-lactamase_156_151,TEM-1,beta-lactamase_156,P62593,0.977966,NO,151,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-2.96,-5.124,2.164,,0.594,H,A,0.17,0.1,1.401,,77.62,HBP,-2.34767,0.111618,0.00216946,0.977966 beta-lactamase_156_M127V,beta-lactamase_156_127,TEM-1,beta-lactamase_156,P62593,0.977966,NO,127,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-2.251,-2.333,0.082,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.111618,0.00437927,0.977966 beta-lactamase_156_G226P,beta-lactamase_156_226,TEM-1,beta-lactamase_156,P62593,0.977968,NO,226,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.461,-3.96,2.499,,0.701,T,l,0.29,-0.25,3.199,,74.48,HOH,-1.42933,0.111618,0.00665294,0.977968 beta-lactamase_156_L55M,beta-lactamase_156_55,TEM-1,beta-lactamase_156,P62593,0.977977,NO,55,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.86,-4.329,2.469,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.111618,0.00403741,0.977977 beta-lactamase_2500_E279L,beta-lactamase_2500_279,TEM-1,beta-lactamase_2500,P62593,0.977979,NO,279,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.361275,0.0192826,0.977979 beta-lactamase_L146F,beta-lactamase_146,TEM-1,beta-lactamase,P62593,0.977984,NO,146,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.462,-2.298,0.836,5.62483,0.007,H,A,1.3,-0.56,1.953,,64.69,AHP,-1.656,0.221079,0.00474542,0.977984 beta-lactamase_625_H287C,beta-lactamase_625_287,TEM-1,beta-lactamase_625,P62593,0.977993,NO,287,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,,,,,,,,,,,,,BBH,-1.111,0.213352,,0.977993 beta-lactamase_625_N98Q,beta-lactamase_625_98,TEM-1,beta-lactamase_625,P62593,0.978003,NO,98,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-2.973,-2.336,-0.637,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.213352,0.00505389,0.978003 beta-lactamase_625_M270Y,beta-lactamase_625_270,TEM-1,beta-lactamase_625,P62593,0.978005,NO,270,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.213352,0.00767762,0.978005 beta-lactamase_156_D48S,beta-lactamase_156_48,TEM-1,beta-lactamase_156,P62593,0.978011,NO,48,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.101,-3.25,2.149,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.111618,0.0027273,0.978011 beta-lactamase_0_D113Q,beta-lactamase_0_113,TEM-1,beta-lactamase_0,P62593,0.978017,NO,113,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.829,-2.873,1.044,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.0500837,0.00474112,0.978017 kka2_1:2_G21A,kka2_1:2_21,Kka2,kka2_1:2,P00552,0.978019,NO,21,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.368,-2.331,0.963,,0.586,T,l,0.29,-0.75,2.026,,71.59,HOH,-2.10167,0.295029,0.00709648,0.978019 beta-lactamase_39_M180S,beta-lactamase_39_180,TEM-1,beta-lactamase_39,P62593,0.978025,NO,180,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-2.795,-2.032,-0.763,,0.242,,B,0.55,-0.94,3.579,,77.62,PHO,-1.56433,0.0495842,0.00552048,0.978025 beta-lactamase_156_D33K,beta-lactamase_156_33,TEM-1,beta-lactamase_156,P62593,0.978027,NO,33,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.321,-3.459,1.138,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.111618,0.00435556,0.978027 beta-lactamase_156_L199D,beta-lactamase_156_199,TEM-1,beta-lactamase_156,P62593,0.978031,NO,199,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-2.942,-3.009,0.067,,0.832,H,A,0.55,0.42,1.552,,77.62,PHH,-2.32933,0.111618,0.0048649,0.978031 beta-lactamase_156_L89F,beta-lactamase_156_89,TEM-1,beta-lactamase_156,P62593,0.978063,NO,89,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.096,-3.844,2.748,,0.168,T,A,0.55,0.63,2.633,,64.34,PHO,-1.75767,0.111618,0.00207068,0.978063 beta-lactamase_2500_K144F,beta-lactamase_2500_144,TEM-1,beta-lactamase_2500,P62593,0.978081,NO,144,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-2.388,-4.427,2.039,,0.863,H,A,2.34,1.27,0.515,,77.62,OBA,-1.904,0.361275,0.00481141,0.978081 beta-lactamase_156_R242I,beta-lactamase_156_242,TEM-1,beta-lactamase_156,P62593,0.978086,NO,242,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.111618,0.00452879,0.978086 PSD95pdz3_A390F,PSD95pdz3_390,PSD95pdz3,PSD95pdz3,P31016,0.978091,NO,390,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.307,-3.749,2.442,5.03823,,,,,12.46,,,,HHP,-1.54467,0.0758425,0.00104603,0.978091 Pab1_N187F,Pab1_187,Pab1,Pab1,P04147,0.978094,NO,187,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-1.224,-4.162,2.938,,0.456,S,b,,1.87,,,,HPO,-1.272,0.175299,0.00083165,0.978094 beta-lactamase_39_K53H,beta-lactamase_39_53,TEM-1,beta-lactamase_39,P62593,0.978095,NO,53,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-2.313,-4.67,2.357,,0.589,,B,2.34,1.15,15.633,15.633,77.62,OBH,-2.1,0.0495842,0.00383383,0.978095 beta-lactamase_625_R176W,beta-lactamase_625_176,TEM-1,beta-lactamase_625,P62593,0.978096,NO,176,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-0.863,-5.322,4.459,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.213352,0.00105554,0.978096 beta-lactamase_39_I261M,beta-lactamase_39_261,TEM-1,beta-lactamase_39,P62593,0.978112,NO,261,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.0495842,0.0123091,0.978112 beta-lactamase_0_L188R,beta-lactamase_0_188,TEM-1,beta-lactamase_0,P62593,0.978114,NO,188,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.166,-3.976,2.81,,,H,A,0.55,-0.3,2.739,,60.14,PHB,-1.47033,0.0500837,0.00295687,0.978114 beta-lactamase_156_L49N,beta-lactamase_156_49,TEM-1,beta-lactamase_156,P62593,0.978121,NO,49,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.897,-3.842,1.945,,0.131,T,A,0.55,0.04,3.112,,64.69,AHP,-1.99233,0.111618,0.00401477,0.978121 beta-lactamase_39_T116Y,beta-lactamase_39_116,TEM-1,beta-lactamase_39,P62593,0.978123,NO,116,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.28,-4.295,3.015,,0.115,E,B,0.22,-0.12,1.133,,67.48,HPH,-1.39967,0.0495842,0.00336175,0.978123 Pab1_L133F,Pab1_133,Pab1,Pab1,P04147,0.978129,NO,133,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.039,-3.434,2.395,,0.015,,B,1.75,1.03,,,,PHB,-1.22,0.175299,0.000345939,0.978129 beta-lactamase_156_G249S,beta-lactamase_156_249,TEM-1,beta-lactamase_156,P62593,0.978133,NO,249,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.111618,0.00220169,0.978133 beta-lactamase_156_L111E,beta-lactamase_156_111,TEM-1,beta-lactamase_156,P62593,0.978133,NO,111,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.76,-3.773,2.013,,0.328,T,A,0.55,0.93,2.26,,64.34,BHP,-1.884,0.111618,0.00480671,0.978133 beta-lactamase_39_E119N,beta-lactamase_39_119,TEM-1,beta-lactamase_39,P62593,0.978139,NO,119,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.412,-3.591,2.179,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.0495842,0.00386966,0.978139 Pab1_S155C,Pab1_155,Pab1,Pab1,P04147,0.97814,NO,155,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.039,-1.541,-0.498,,,,,,,,,,PPB,-1.42267,0.175299,0.00208179,0.97814 beta-lactamase_625_Q203E,beta-lactamase_625_203,TEM-1,beta-lactamase_625,P62593,0.978142,NO,203,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.168,-2.449,0.281,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.213352,0.00631514,0.978142 beta-lactamase_156_K213S,beta-lactamase_156_213,TEM-1,beta-lactamase_156,P62593,0.978152,NO,213,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.81,-3.351,1.541,,0.67,,A,2.34,0.29,3.924,,67.83,ABH,-1.57767,0.111618,0.00610411,0.978152 beta-lactamase_156_T269Y,beta-lactamase_156_269,TEM-1,beta-lactamase_156,P62593,0.978155,NO,269,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.111618,0.00950944,0.978155 beta-lactamase_156_L205C,beta-lactamase_156_205,TEM-1,beta-lactamase_156,P62593,0.978161,NO,205,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.922,-4.692,3.77,,,H,A,0.55,-0.46,0.678,,42.31,PHH,-1.57767,0.111618,0.00255802,0.978161 beta-lactamase_2500_K32V,beta-lactamase_2500_32,TEM-1,beta-lactamase_2500,P62593,0.978161,NO,32,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.984,-3.477,1.493,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.361275,0.00401283,0.978161 beta-lactamase_625_K213V,beta-lactamase_625_213,TEM-1,beta-lactamase_625,P62593,0.978162,NO,213,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.81,-3.705,1.895,,0.67,,A,2.34,0.29,3.924,,67.83,ABH,-1.57767,0.213352,0.00610411,0.978162 beta-lactamase_2500_H94I,beta-lactamase_2500_94,TEM-1,beta-lactamase_2500,P62593,0.978173,NO,94,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-2.5,-2.913,0.413,,0.776,,B,0.17,1.24,1.176,,77.62,HBH,-1.872,0.361275,0.00389226,0.978173 beta-lactamase_39_D212N,beta-lactamase_39_212,TEM-1,beta-lactamase_39,P62593,0.978174,NO,212,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.624,-1.899,0.275,,0.037,,b,0.75,-0.58,10.748,10.748,74.48,HAB,-1.77667,0.0495842,0.00644302,0.978174 beta-lactamase_39_E62S,beta-lactamase_39_62,TEM-1,beta-lactamase_39,P62593,0.978181,NO,62,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.193,-3.245,2.052,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.0495842,0.00264802,0.978181 beta-lactamase_F22G,beta-lactamase_22,TEM-1,beta-lactamase,P62593,0.978181,NO,22,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-2.676,-2.756,0.08,,,,,,,1.616,,73.08,HHH,-2.03233,0.221079,0.00262842,0.978181 beta-lactamase_K284I,beta-lactamase_284,TEM-1,beta-lactamase,P62593,0.978181,NO,284,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.981,-4.042,2.061,6.30084,0.848,H,A,1.82,0.67,1.931,,77.62,HBB,-1.82133,0.221079,0.0686156,0.978181 beta-lactamase_L199F,beta-lactamase_199,TEM-1,beta-lactamase,P62593,0.978181,NO,199,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-2.942,-4.403,1.461,5.57712,0.832,H,A,0.82,0.42,15.302,15.302,77.62,PHH,-2.32933,0.221079,0.0048649,0.978181 beta-lactamase_L28V,beta-lactamase_28,TEM-1,beta-lactamase,P62593,0.978181,NO,28,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.579,-1.979,0.4,5.42969,0.277,H,A,0.07,-0.16,19.748,19.748,93.01,PHH,-2.11333,0.221079,0.00359321,0.978181 beta-lactamase_P217N,beta-lactamase_217,TEM-1,beta-lactamase,P62593,0.978181,NO,217,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-2.062,-2.997,0.935,5.19872,0.496,I,A,0.99,-0.33,0.431,,74.48,OOH,-1.64333,0.221079,0.00463211,0.978181 beta-lactamase_Q4C,beta-lactamase_4,TEM-1,beta-lactamase,P62593,0.978181,NO,4,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,,-4.982,2.418,,,,,,,,,,HPB,,0.221079,0.00316562,0.978181 beta-lactamase_Q97W,beta-lactamase_97,TEM-1,beta-lactamase,P62593,0.978181,NO,97,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.072,-5.457,3.385,6.30204,0.823,G,A,1.1,2.42,1.157,,77.62,PPP,-2.43833,0.221079,0.0045116,0.978181 beta-lactamase_T107S,beta-lactamase_107,TEM-1,beta-lactamase,P62593,0.978181,NO,107,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.117,-1.871,0.754,5.23432,,G,A,2.12,-0.06,3.676,,67.83,HPA,-1.265,0.221079,0.00239347,0.978181 beta-lactamase_V29M,beta-lactamase_29,TEM-1,beta-lactamase,P62593,0.978181,NO,29,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-2.856,-4.721,1.865,5.58481,0.733,H,A,0.23,-0.78,1.287,,93.01,HHB,-2.24733,0.221079,0.00318969,0.978181 beta-lactamase_0_A246M,beta-lactamase_0_246,TEM-1,beta-lactamase_0,P62593,0.978219,NO,246,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.121,-2.882,0.761,,0.01,E,B,0.46,-1.01,1.201,,73.78,HHH,-1.55633,0.0500837,0.00569458,0.978219 beta-lactamase_625_K30N,beta-lactamase_625_30,TEM-1,beta-lactamase_625,P62593,0.978221,NO,30,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-2.307,-2.865,0.558,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.213352,0.00448593,0.978221 beta-lactamase_625_G216W,beta-lactamase_625_216,TEM-1,beta-lactamase_625,P62593,0.978226,NO,216,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.477,-5.45,3.973,,0.437,I,A,0.29,-0.58,1.718,,74.48,HOO,-1.68067,0.213352,0.00639568,0.978226 beta-lactamase_156_E62L,beta-lactamase_156_62,TEM-1,beta-lactamase_156,P62593,0.978227,NO,62,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.193,-3.66,2.467,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.111618,0.00264802,0.978227 beta-lactamase_39_Q204K,beta-lactamase_39_204,TEM-1,beta-lactamase_39,P62593,0.978228,NO,204,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-1.382,-2.218,0.836,,0.204,H,A,0.64,0.09,0.489,,66.08,PPH,-1.49067,0.0495842,0.00364106,0.978228 beta-lactamase_39_T138Q,beta-lactamase_39_138,TEM-1,beta-lactamase_39,P62593,0.978229,NO,138,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.506,-3.82,1.314,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.0495842,0.00487868,0.978229 beta-lactamase_39_L111G,beta-lactamase_39_111,TEM-1,beta-lactamase_39,P62593,0.978238,NO,111,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.76,-3.666,1.906,,0.328,T,A,0.55,0.93,4.334,,64.34,BHP,-1.884,0.0495842,0.00480671,0.978238 beta-lactamase_2500_P25I,beta-lactamase_2500_25,TEM-1,beta-lactamase_2500,P62593,0.97824,NO,25,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.526,-4.029,2.503,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.361275,0.00347571,0.97824 beta-lactamase_2500_T116S,beta-lactamase_2500_116,TEM-1,beta-lactamase_2500,P62593,0.978241,NO,116,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.28,-1.932,0.652,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.361275,0.00336175,0.978241 beta-lactamase_625_K213N,beta-lactamase_625_213,TEM-1,beta-lactamase_625,P62593,0.978241,NO,213,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.81,-3.623,1.813,,0.67,,A,2.34,0.29,3.924,,67.83,ABH,-1.57767,0.213352,0.00610411,0.978241 PSD95pdz3_A375S,PSD95pdz3_375,PSD95pdz3,PSD95pdz3,P31016,0.978245,NO,375,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.307,-2.617,1.31,5.05512,,,,,13.888,,,,PHH,-1.43767,0.0758425,0.000356809,0.978245 beta-lactamase_39_Y44H,beta-lactamase_39_44,TEM-1,beta-lactamase_39,P62593,0.978249,NO,44,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-2.547,-4.769,2.222,,,E,B,0.21,-0.45,2.683,,73.78,OHH,-1.86267,0.0495842,0.00426364,0.978249 PSD95pdz3_I314Q,PSD95pdz3_314,PSD95pdz3,PSD95pdz3,P31016,0.978252,NO,314,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.628,-4.03,2.402,5.39919,,,,,15.7775,0.397,,81.35,BHH,-1.61167,0.0758425,0.0012606,0.978252 beta-lactamase_39_R159L,beta-lactamase_39_159,TEM-1,beta-lactamase_39,P62593,0.978253,NO,159,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-0.94,-3.407,2.467,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.0495842,0.00108472,0.978253 kka2_1:2_G164W,kka2_1:2_164,Kka2,kka2_1:2,P00552,0.978255,NO,164,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.869,-5.307,4.438,,0.862,T,l,0.75,1.45,1.539,,64.39,POH,-1.828,0.295029,0.00442091,0.978255 beta-lactamase_156_E35T,beta-lactamase_156_35,TEM-1,beta-lactamase_156,P62593,0.978274,NO,35,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-0.869,-3.447,2.578,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.111618,0.00174441,0.978274 beta-lactamase_156_G90P,beta-lactamase_156_90,TEM-1,beta-lactamase_156,P62593,0.978277,NO,90,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-2.091,-3.952,1.861,,0.598,T,A,0.29,0.32,0.319,,77.62,HOB,-1.52633,0.111618,0.00490273,0.978277 beta-lactamase_T147R,beta-lactamase_147,TEM-1,beta-lactamase,P62593,0.978283,NO,147,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.149,-3.809,2.66,5.37474,0.281,H,A,0.8,-0.68,2.838,,64.34,HPH,-1.456,0.221079,0.00226017,0.978283 PSD95pdz3_S371D,PSD95pdz3_371,PSD95pdz3,PSD95pdz3,P31016,0.978283,NO,371,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.86,-3.15,1.29,5.19744,,,,,17.1117,3.854,,87.71,HPB,-1.598,0.0758425,0.000847873,0.978283 beta-lactamase_2500_P250K,beta-lactamase_2500_250,TEM-1,beta-lactamase_2500,P62593,0.978289,NO,250,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.361275,0.00550899,0.978289 beta-lactamase_I256L,beta-lactamase_256,TEM-1,beta-lactamase,P62593,0.97829,NO,256,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.621,-1.922,0.301,5.3196,,E,B,1,-0.84,1.615,,73.08,BHH,-1.80667,0.221079,0.00710634,0.97829 beta-lactamase_625_E272F,beta-lactamase_625_272,TEM-1,beta-lactamase_625,P62593,0.978291,NO,272,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.213352,0.00545371,0.978291 beta-lactamase_39_H94C,beta-lactamase_39_94,TEM-1,beta-lactamase_39,P62593,0.978299,NO,94,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-2.5,-5.143,2.643,,0.776,,B,0.17,1.24,11.583,11.583,77.62,HBH,-1.872,0.0495842,0.00389226,0.978299 beta-lactamase_39_T147P,beta-lactamase_39_147,TEM-1,beta-lactamase_39,P62593,0.978299,NO,147,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.149,-3.818,2.669,,0.281,H,A,0.22,-0.68,13.843,13.843,64.34,HPH,-1.456,0.0495842,0.00226017,0.978299 beta-lactamase_625_E62Y,beta-lactamase_625_62,TEM-1,beta-lactamase_625,P62593,0.9783,NO,62,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.193,-4.285,3.092,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.213352,0.00264802,0.9783 Pab1_A178P,Pab1_178,Pab1,Pab1,P04147,0.978306,NO,178,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.579,-3.674,2.095,,0.019,H,A,0.64,0.64,2.7,,81.63,OHH,-1.61067,0.175299,0.00160192,0.978306 beta-lactamase_0_L196Y,beta-lactamase_0_196,TEM-1,beta-lactamase_0,P62593,0.978326,NO,196,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-2.478,-4.286,1.808,,0.518,S,A,0.55,1.35,6.513,6.513,77.62,AHH,-1.839,0.0500837,0.00512144,0.978326 beta-lactamase_156_L146C,beta-lactamase_156_146,TEM-1,beta-lactamase_156,P62593,0.97833,NO,146,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.462,-4.847,3.385,,0.007,H,A,0.55,-0.56,1.578,,64.69,AHP,-1.656,0.111618,0.00474542,0.97833 Pab1_E176D,Pab1_176,Pab1,Pab1,P04147,0.978345,NO,176,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.003,-1.972,-0.031,,,,,,,,,,AAO,-2.09933,0.175299,0.00264426,0.978345 beta-lactamase_156_G226K,beta-lactamase_156_226,TEM-1,beta-lactamase_156,P62593,0.978346,NO,226,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.461,-2.859,1.398,,0.701,T,l,0.29,-0.25,3.199,,74.48,HOH,-1.42933,0.111618,0.00665294,0.978346 beta-lactamase_39_A170F,beta-lactamase_39_170,TEM-1,beta-lactamase_39,P62593,0.978348,NO,170,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.237,-2.633,1.396,,0.126,,L,0.46,-0.35,3.7,,64.69,AHH,-1.63267,0.0495842,0.00431903,0.978348 beta-lactamase_0_Y44G,beta-lactamase_0_44,TEM-1,beta-lactamase_0,P62593,0.978351,NO,44,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-2.547,-3.687,1.14,,,E,B,0.21,-0.45,1.751,,73.78,OHH,-1.86267,0.0500837,0.00426364,0.978351 beta-lactamase_39_S122V,beta-lactamase_39_122,TEM-1,beta-lactamase_39,P62593,0.978353,NO,122,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.406,-2.967,0.561,,0.352,H,A,0.27,-0.54,2.004,,77.62,OPH,-1.39767,0.0495842,0.00497825,0.978353 beta-lactamase_156_E272W,beta-lactamase_156_272,TEM-1,beta-lactamase_156,P62593,0.978359,NO,272,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.111618,0.00545371,0.978359 beta-lactamase_2500_T198G,beta-lactamase_2500_198,TEM-1,beta-lactamase_2500,P62593,0.978364,NO,198,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.168,-3.295,1.127,,0.489,,B,0.22,-0.13,0.37,,73.78,HPH,-1.98767,0.361275,0.004311,0.978364 beta-lactamase_156_D231K,beta-lactamase_156_231,TEM-1,beta-lactamase_156,P62593,0.978372,NO,231,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.816,-3.42,2.604,,,E,B,0.75,-1.06,2.66,,65.38,HAB,-0.994,0.111618,0.00107395,0.978372 beta-lactamase_156_K254R,beta-lactamase_156_254,TEM-1,beta-lactamase_156,P62593,0.978373,NO,254,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.111618,0.00369,0.978373 beta-lactamase_0_S201D,beta-lactamase_0_201,TEM-1,beta-lactamase_0,P62593,0.978376,NO,201,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.183,-3.453,2.27,,0.064,H,A,0.27,-0.07,3.54,,64.69,HPB,-1.451,0.0500837,0.00198815,0.978376 PSD95pdz3_D348E,PSD95pdz3_348,PSD95pdz3,PSD95pdz3,P31016,0.978379,NO,348,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.264,-2.447,1.183,5.02473,,,,,16.8925,,,,HAH,-1.306,0.0758425,0.000731866,0.978379 beta-lactamase_156_E102R,beta-lactamase_156_102,TEM-1,beta-lactamase_156,P62593,0.978388,NO,102,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.118,-3.801,1.683,,0.722,S,B,1.04,1.82,15.721,15.721,73.08,HAH,-1.581,0.111618,0.00486633,0.978388 beta-lactamase_L38M,beta-lactamase_38,TEM-1,beta-lactamase,P62593,0.978388,NO,38,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.343,-4.186,2.843,5.23728,0.088,H,A,1.75,0.2,1.986,,64.34,PHO,-1.78033,0.221079,0.00373244,0.978388 beta-lactamase_625_L146V,beta-lactamase_625_146,TEM-1,beta-lactamase_625,P62593,0.978392,NO,146,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.462,-1.839,0.377,,0.007,H,A,0.55,-0.56,2.16,,64.69,AHP,-1.656,0.213352,0.00474542,0.978392 beta-lactamase_2500_T187S,beta-lactamase_2500_187,TEM-1,beta-lactamase_2500,P62593,0.978396,NO,187,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.401,-2.134,0.733,,0.007,H,A,0.22,-1.19,3.91,,67.48,PPH,-1.69633,0.361275,0.00491782,0.978396 beta-lactamase_39_H94Y,beta-lactamase_39_94,TEM-1,beta-lactamase_39,P62593,0.978398,NO,94,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-2.5,-4.209,1.709,,0.776,,B,0.17,1.24,11.583,11.583,77.62,HBH,-1.872,0.0495842,0.00389226,0.978398 beta-lactamase_M180G,beta-lactamase_180,TEM-1,beta-lactamase,P62593,0.978399,NO,180,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-2.795,-3.389,0.594,4.96809,0.242,,B,1.07,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.221079,0.00552048,0.978399 beta-lactamase_156_D252M,beta-lactamase_156_252,TEM-1,beta-lactamase_156,P62593,0.978418,NO,252,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.111618,0.00575769,0.978418 Pab1_N192K,Pab1_192,Pab1,Pab1,P04147,0.978419,NO,192,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-1.079,-3.049,1.97,,0.619,T,l,,2.28,,,,HPO,-1.231,0.175299,0.000273498,0.978419 PSD95pdz3_N363D,PSD95pdz3_363,PSD95pdz3,PSD95pdz3,P31016,0.978423,NO,363,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-1.41,-2.7,1.29,5.23349,,,,,20.7037,,,,HPO,-1.29433,0.0758425,0.000524014,0.978423 beta-lactamase_39_G154T,beta-lactamase_39_154,TEM-1,beta-lactamase_39,P62593,0.978443,NO,154,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.823,-3.619,2.796,,0.54,T,l,0.29,-0.56,1.151,,64.69,HOA,-1.635,0.0495842,0.00180205,0.978443 kka2_1:8_L94T,kka2_1:8_94,Kka2,kka2_1:8,P00552,0.978444,NO,94,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.618,-2.787,1.169,,0.058,E,B,1.59,-0.52,2.197,,56.06,HHO,-1.612,0.100394,0.00520888,0.978444 kka2_1:8_L94T,kka2_1:8_94,Kka2,kka2_1:8,P00552,0.978444,NO,94,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.618,-2.787,1.169,,0.058,E,B,1.59,-0.52,2.197,,56.06,HHO,-1.612,0.100394,0.00520888,0.978444 beta-lactamase_156_V101N,beta-lactamase_156_101,TEM-1,beta-lactamase_156,P62593,0.978445,NO,101,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.295,-4.085,2.79,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.111618,0.00374492,0.978445 beta-lactamase_156_M153V,beta-lactamase_156_153,TEM-1,beta-lactamase_156,P62593,0.978451,NO,153,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-3.193,-2.524,-0.669,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.111618,0.00509109,0.978451 beta-lactamase_39_I54C,beta-lactamase_39_54,TEM-1,beta-lactamase_39,P62593,0.978458,NO,54,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-2.838,-5.056,2.218,,0.669,E,B,0.48,-0.14,1.349,,73.78,BHH,-2.337,0.0495842,0.00403589,0.978458 beta-lactamase_A148F,beta-lactamase_148,TEM-1,beta-lactamase,P62593,0.978459,NO,148,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.757,-4.389,2.632,5.28111,0.379,H,A,0.52,-0.55,2.117,,72.73,PHH,-1.40167,0.221079,0.00547053,0.978459 beta-lactamase_D269R,beta-lactamase_269,TEM-1,beta-lactamase,P62593,0.978459,NO,269,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.156,-3.041,0.885,5.47645,0.646,H,A,0.23,0.4,21.796,21.796,77.62,HAA,-1.96733,0.221079,0.00950944,0.978459 beta-lactamase_E108R,beta-lactamase_108,TEM-1,beta-lactamase,P62593,0.978459,NO,108,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.46,-2.885,1.425,5.52079,0.572,G,A,0.52,1.87,1.973,,72.73,PAB,-1.437,0.221079,0.00413372,0.978459 beta-lactamase_V31L,beta-lactamase_31,TEM-1,beta-lactamase,P62593,0.978459,NO,31,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.822,-2.16,0.338,5.43781,,H,A,2.78,-0.46,2.885,,73.78,BHB,-2.03767,0.221079,0.00478065,0.978459 beta-lactamase_625_R239E,beta-lactamase_625_239,TEM-1,beta-lactamase_625,P62593,0.978466,NO,239,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.213352,0.00213852,0.978466 beta-lactamase_0_G142N,beta-lactamase_0_142,TEM-1,beta-lactamase_0,P62593,0.978469,NO,142,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.707,-3.445,2.738,,0.034,,p,0.29,-0.64,1.947,,64.69,OOO,-0.834,0.0500837,0.00060149,0.978469 beta-lactamase_39_N152V,beta-lactamase_39_152,TEM-1,beta-lactamase_39,P62593,0.978482,NO,152,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-2.757,-3.616,0.859,,0.863,H,A,0.61,0.92,4.038,,77.62,BPH,-2.97,0.0495842,0.00471429,0.978482 beta-lactamase_2500_E166R,beta-lactamase_2500_166,TEM-1,beta-lactamase_2500,P62593,0.978483,NO,166,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.756,-3.805,2.049,,0.508,G,A,1.04,1.05,2.124,,73.08,OAH,-1.42233,0.361275,0.00512989,0.978483 beta-lactamase_0_K144A,beta-lactamase_0_144,TEM-1,beta-lactamase_0,P62593,0.978486,NO,144,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-2.388,-2.013,-0.375,,0.863,H,A,2.34,1.27,5.696,,77.62,OBA,-1.904,0.0500837,0.00481141,0.978486 beta-lactamase_156_L223W,beta-lactamase_156_223,TEM-1,beta-lactamase_156,P62593,0.978494,NO,223,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.055,-5.101,4.046,,0.27,,B,0.55,0.09,1.511,,74.48,HHO,-1.35033,0.111618,0.00372793,0.978494 beta-lactamase_156_D231H,beta-lactamase_156_231,TEM-1,beta-lactamase_156,P62593,0.978504,NO,231,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.816,-4.453,3.637,,,E,B,0.75,-1.06,2.66,,65.38,HAB,-0.994,0.111618,0.00107395,0.978504 beta-lactamase_156_R239V,beta-lactamase_156_239,TEM-1,beta-lactamase_156,P62593,0.978511,NO,239,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.111618,0.00213852,0.978511 hsp90_N588T,hsp90_588,hsp90,hsp90,P02829,0.978548,NO,588,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-3.051,-2.8,0,4.61142,0.019,H,A,0.14,0.39,,,,HPH,-3.12167,0.368192,0.000222939,0.978548 kka2_1:8_D90K,kka2_1:8_90,Kka2,kka2_1:8,P00552,0.978549,NO,90,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.459,-3.563,1.104,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.100394,0.00583842,0.978549 kka2_1:8_D90K,kka2_1:8_90,Kka2,kka2_1:8,P00552,0.978549,NO,90,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.459,-3.563,1.104,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.100394,0.00583842,0.978549 beta-lactamase_0_S104G,beta-lactamase_0_104,TEM-1,beta-lactamase_0,P62593,0.97855,NO,104,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.015,-3.017,2.002,,0.04,,b,0.27,0.57,1.148,,63.29,HPO,-1.05267,0.0500837,0.00218083,0.97855 beta-lactamase_0_M115G,beta-lactamase_0_115,TEM-1,beta-lactamase_0,P62593,0.978551,NO,115,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.389,-3.632,2.243,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.0500837,0.0034337,0.978551 beta-lactamase_625_V82Y,beta-lactamase_625_82,TEM-1,beta-lactamase_625,P62593,0.978554,NO,82,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.325,-4.133,2.808,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.213352,0.00397046,0.978554 beta-lactamase_156_Q86C,beta-lactamase_156_86,TEM-1,beta-lactamase_156,P62593,0.978555,NO,86,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.4,-5.132,2.732,,0.696,S,A,0.64,2.38,27.704,27.704,77.62,OPA,-1.61067,0.111618,0.00450027,0.978555 beta-lactamase_39_E195Q,beta-lactamase_39_195,TEM-1,beta-lactamase_39,P62593,0.978565,NO,195,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.186,-2.527,0.341,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.0495842,0.00496565,0.978565 beta-lactamase_625_I171C,beta-lactamase_625_171,TEM-1,beta-lactamase_625,P62593,0.978569,NO,171,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-2.431,-4.938,2.507,,0.361,,B,0.48,0.53,3.869,,77.62,HHO,-1.55533,0.213352,0.00623355,0.978569 beta-lactamase_0_K109P,beta-lactamase_0_109,TEM-1,beta-lactamase_0,P62593,0.978572,NO,109,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.734,-2.825,1.091,,0.787,G,A,2.34,2.21,15.473,15.473,72.73,ABB,-1.63333,0.0500837,0.00462493,0.978572 beta-lactamase_39_G85N,beta-lactamase_39_85,TEM-1,beta-lactamase_39,P62593,0.978572,NO,85,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.011,-3.501,2.49,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.0495842,0.00252173,0.978572 beta-lactamase_39_E56T,beta-lactamase_39_56,TEM-1,beta-lactamase_39,P62593,0.978574,NO,56,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.043,-2.013,-0.03,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.0495842,0.00238534,0.978574 beta-lactamase_2500_K144A,beta-lactamase_2500_144,TEM-1,beta-lactamase_2500,P62593,0.978576,NO,144,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-2.388,-2.013,-0.375,,0.863,H,A,2.34,1.27,0.515,,77.62,OBA,-1.904,0.361275,0.00481141,0.978576 beta-lactamase_0_C75P,beta-lactamase_0_75,TEM-1,beta-lactamase_0,P62593,0.978584,NO,75,C,P,CP,Special,Special,5.07,6.3,1.23,169,121,115,-6,108.5,112.7,4.2,-1.245,-4.012,2.767,,,H,A,0.46,-0.87,2.256,,50,HOO,-1.24333,0.0500837,0.0034616,0.978584 beta-lactamase_0_P60K,beta-lactamase_0_60,TEM-1,beta-lactamase_0,P62593,0.978584,NO,60,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-2.469,-3.557,1.088,,0.256,T,A,0.52,-0.56,3.653,,77.62,BOA,-1.97633,0.0500837,0.00521318,0.978584 beta-lactamase_625_D252G,beta-lactamase_625_252,TEM-1,beta-lactamase_625,P62593,0.978586,NO,252,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.213352,0.00575769,0.978586 beta-lactamase_39_D207Y,beta-lactamase_39_207,TEM-1,beta-lactamase_39,P62593,0.978587,NO,207,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.064,-4.317,2.253,,0.409,H,A,0.75,0.12,14.511,14.511,77.62,HAH,-1.77033,0.0495842,0.00592942,0.978587 PSD95pdz3_N381D,PSD95pdz3_381,PSD95pdz3,PSD95pdz3,P31016,0.978587,NO,381,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-1.41,-2.7,1.29,5.66057,,,,,28.2162,,,,BPH,-1.37767,0.0758425,0.000265374,0.978587 beta-lactamase_H151T,beta-lactamase_151,TEM-1,beta-lactamase,P62593,0.978604,NO,151,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-2.96,-3.492,0.532,5.47408,0.594,H,A,0.35,0.1,1.843,,77.62,HBP,-2.34767,0.221079,0.00216946,0.978604 beta-lactamase_P172Y,beta-lactamase_172,TEM-1,beta-lactamase,P62593,0.978604,NO,172,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.998,-4.368,3.37,5.98941,0.639,T,b,1.1,0.24,2.087,,74.48,HOP,-2.03067,0.221079,0.00312594,0.978604 beta-lactamase_S2K,beta-lactamase_2,TEM-1,beta-lactamase,P62593,0.978604,NO,2,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.942,-3.387,1.445,,,,,,,2.36,,65.38,HPH,-2.02767,0.221079,0.00227352,0.978604 beta-lactamase_T69T,beta-lactamase_69,TEM-1,beta-lactamase,P62593,0.978604,NO,69,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-0.973,-0.973,,5.16042,,G,A,0.69,-1.24,0.505,,93.01,PPH,-1.01833,0.221079,0.00127498,0.978604 beta-lactamase_2500_D207Q,beta-lactamase_2500_207,TEM-1,beta-lactamase_2500,P62593,0.978616,NO,207,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.064,-2.209,0.145,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.361275,0.00592942,0.978616 beta-lactamase_39_D271P,beta-lactamase_39_271,TEM-1,beta-lactamase_39,P62593,0.97863,NO,271,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.0495842,0.00752082,0.97863 beta-lactamase_39_D33T,beta-lactamase_39_33,TEM-1,beta-lactamase_39,P62593,0.978639,NO,33,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.321,-2.667,0.346,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.0495842,0.00435556,0.978639 beta-lactamase_39_Q86K,beta-lactamase_39_86,TEM-1,beta-lactamase_39,P62593,0.97864,NO,86,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.4,-2.554,0.154,,0.696,S,A,0.64,2.38,27.704,27.704,77.62,OPA,-1.61067,0.0495842,0.00450027,0.97864 beta-lactamase_39_Q88H,beta-lactamase_39_88,TEM-1,beta-lactamase_39,P62593,0.978651,NO,88,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.086,-4.599,2.513,,0.807,,B,0.64,2.03,11.108,11.108,77.62,APH,-1.53433,0.0495842,0.00504167,0.978651 beta-lactamase_A124T,beta-lactamase_124,TEM-1,beta-lactamase,P62593,0.978654,NO,124,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.181,-1.586,0.405,4.58507,,H,A,0.58,-0.9,2.273,,64.34,HHH,-1.152,0.221079,0.00481399,0.978654 beta-lactamase_2500_Q267F,beta-lactamase_2500_267,TEM-1,beta-lactamase_2500,P62593,0.978655,NO,267,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.361275,0.0102128,0.978655 beta-lactamase_156_D252G,beta-lactamase_156_252,TEM-1,beta-lactamase_156,P62593,0.978667,NO,252,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.111618,0.00575769,0.978667 WW_domain_S184V,WW_domain_184,Yap65,WW_domain,P46937,0.978667,NO,184,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.363,-3.218,1.855,5.06696,,,,,,,,,PPO,-1.39133,0.153962,0.00231095,0.978667 beta-lactamase_39_P181S,beta-lactamase_39_181,TEM-1,beta-lactamase_39,P62593,0.978669,NO,181,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.813,-3.349,2.536,,,H,A,0.52,-1.14,1.946,,61.54,HOH,-1.795,0.0495842,0.000703122,0.978669 beta-lactamase_0_A132C,beta-lactamase_0_132,TEM-1,beta-lactamase_0,P62593,0.978674,NO,132,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.9,-4.503,3.603,,,H,A,0.46,-0.93,2.249,,64.69,PHH,-1.138,0.0500837,0.000962524,0.978674 beta-lactamase_156_H151P,beta-lactamase_156_151,TEM-1,beta-lactamase_156,P62593,0.978677,NO,151,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-2.96,-3.911,0.951,,0.594,H,A,0.17,0.1,1.401,,77.62,HBP,-2.34767,0.111618,0.00216946,0.978677 beta-lactamase_156_L111K,beta-lactamase_156_111,TEM-1,beta-lactamase_156,P62593,0.97868,NO,111,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.76,-3.773,2.013,,0.328,T,A,0.55,0.93,2.26,,64.34,BHP,-1.884,0.111618,0.00480671,0.97868 beta-lactamase_E145D,beta-lactamase_145,TEM-1,beta-lactamase,P62593,0.978694,NO,145,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.357,-3.52,1.163,5.38104,0.545,H,A,0.52,0.79,2.124,,77.62,BAH,-2.069,0.221079,0.00553285,0.978694 beta-lactamase_E169H,beta-lactamase_169,TEM-1,beta-lactamase,P62593,0.978694,NO,169,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.23,-4.45,3.22,5.78896,0.337,,A,0.52,1,1.806,,73.08,PAH,-1.16533,0.221079,0.00400994,0.978694 beta-lactamase_2500_E145H,beta-lactamase_2500_145,TEM-1,beta-lactamase_2500,P62593,0.978711,NO,145,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.357,-4.656,2.299,,0.545,H,A,1.04,0.79,2.124,,77.62,BAH,-2.069,0.361275,0.00553285,0.978711 beta-lactamase_39_I229C,beta-lactamase_39_229,TEM-1,beta-lactamase_39,P62593,0.978712,NO,229,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.267,-4.722,3.455,,0.083,E,B,0.48,-0.76,1.114,,50,HHH,-1.58767,0.0495842,0.00477249,0.978712 beta-lactamase_2500_P165T,beta-lactamase_2500_165,TEM-1,beta-lactamase_2500,P62593,0.978713,NO,165,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.373,-1.281,-0.092,,0.203,T,A,0.52,-0.31,0.414,,73.78,AOA,-1.359,0.361275,0.00549538,0.978713 beta-lactamase_625_V72C,beta-lactamase_625_72,TEM-1,beta-lactamase_625,P62593,0.978728,NO,72,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.658,-4.8,3.142,,,H,A,0.44,-1.03,0.981,,65.73,BHH,-1.32167,0.213352,0.00501194,0.978728 beta-lactamase_156_A278T,beta-lactamase_156_278,TEM-1,beta-lactamase_156,P62593,0.978736,NO,278,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.111618,0.0310297,0.978736 beta-lactamase_39_R59N,beta-lactamase_39_59,TEM-1,beta-lactamase_39,P62593,0.978737,NO,59,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.345,-2.533,1.188,,0.329,S,L,1.2,-0.09,1.806,,73.08,HBO,-2.24267,0.0495842,0.00318082,0.978737 kka2_1:4_R217K,kka2_1:4_217,Kka2,kka2_1:4,P00552,0.978744,NO,217,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.158,-3.143,1.985,,0.252,T,A,1.2,-0.59,2.074,,52.27,ABH,-1.127,0.168804,0.0047191,0.978744 beta-lactamase_156_L223C,beta-lactamase_156_223,TEM-1,beta-lactamase_156,P62593,0.978757,NO,223,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.055,-4.721,3.666,,0.27,,B,0.55,0.09,1.511,,74.48,HHO,-1.35033,0.111618,0.00372793,0.978757 beta-lactamase_156_R81K,beta-lactamase_156_81,TEM-1,beta-lactamase_156,P62593,0.978766,NO,81,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.466,-2.393,0.927,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.111618,0.00499763,0.978766 beta-lactamase_0_G249T,beta-lactamase_0_249,TEM-1,beta-lactamase_0,P62593,0.978767,NO,249,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.0500837,0.00220169,0.978767 beta-lactamase_39_P181L,beta-lactamase_39_181,TEM-1,beta-lactamase_39,P62593,0.978775,NO,181,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.813,-3.546,2.733,,,H,A,0.52,-1.14,1.946,,61.54,HOH,-1.795,0.0495842,0.000703122,0.978775 beta-lactamase_39_R273N,beta-lactamase_39_273,TEM-1,beta-lactamase_39,P62593,0.978788,NO,273,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.314,-3.744,1.43,,0.564,H,A,1.2,1.57,2.163,,73.78,ABP,-1.841,0.0495842,0.0077952,0.978788 beta-lactamase_156_E46Q,beta-lactamase_156_46,TEM-1,beta-lactamase_156,P62593,0.978789,NO,46,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.94,-4.007,2.067,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.111618,0.00427568,0.978789 beta-lactamase_39_D33H,beta-lactamase_39_33,TEM-1,beta-lactamase_39,P62593,0.978793,NO,33,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.321,-4.654,2.333,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.0495842,0.00435556,0.978793 beta-lactamase_156_G76L,beta-lactamase_156_76,TEM-1,beta-lactamase_156,P62593,0.978795,NO,76,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.189,-3.521,2.332,,,H,A,0.29,-0.67,3.059,,67.83,OOH,-1.22267,0.111618,0.00476637,0.978795 beta-lactamase_156_D271Y,beta-lactamase_156_271,TEM-1,beta-lactamase_156,P62593,0.978796,NO,271,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.111618,0.00752082,0.978796 beta-lactamase_39_G39D,beta-lactamase_39_39,TEM-1,beta-lactamase_39,P62593,0.978811,NO,39,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.864,-2.194,0.33,,0.701,T,L,0.29,0.47,1.454,,77.62,HOH,-1.53633,0.0495842,0.00487611,0.978811 beta-lactamase_39_L73F,beta-lactamase_39_73,TEM-1,beta-lactamase_39,P62593,0.978812,NO,73,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.507,-2.19,0.683,,,H,A,0.55,-0.64,2.09,,67.83,HHH,-1.487,0.0495842,0.00488983,0.978812 beta-lactamase_625_N98G,beta-lactamase_625_98,TEM-1,beta-lactamase_625,P62593,0.978815,NO,98,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-2.973,-3.401,0.428,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.213352,0.00505389,0.978815 beta-lactamase_2500_K286Q,beta-lactamase_2500_286,TEM-1,beta-lactamase_2500,P62593,0.978823,NO,286,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.361275,,0.978823 kka2_1:8_G74C,kka2_1:8_74,Kka2,kka2_1:8,P00552,0.978829,NO,74,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.18,-5.237,4.057,,0.621,T,l,0.29,0.2,2.014,,64.39,POH,-1.91667,0.100394,0.00587035,0.978829 kka2_1:8_G74C,kka2_1:8_74,Kka2,kka2_1:8,P00552,0.978829,NO,74,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.18,-5.237,4.057,,0.621,T,l,0.29,0.2,2.014,,64.39,POH,-1.91667,0.100394,0.00587035,0.978829 beta-lactamase_625_M67D,beta-lactamase_625_67,TEM-1,beta-lactamase_625,P62593,0.97883,NO,67,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-2.231,-3.779,1.548,,0.006,G,P,0.55,-0.81,2.653,,65.03,HHP,-1.502,0.213352,0.00409753,0.97883 beta-lactamase_S80E,beta-lactamase_80,TEM-1,beta-lactamase,P62593,0.978831,NO,80,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.029,-2.666,0.637,5.23748,0.192,H,A,0.25,0.46,2.256,,77.62,HPB,-1.44567,0.221079,0.00565569,0.978831 beta-lactamase_625_R81I,beta-lactamase_625_81,TEM-1,beta-lactamase_625,P62593,0.978848,NO,81,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.466,-4.004,2.538,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.213352,0.00499763,0.978848 beta-lactamase_39_M184I,beta-lactamase_39_184,TEM-1,beta-lactamase_39,P62593,0.978851,NO,184,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.593,-2.332,0.739,,,H,A,0.55,-0.87,2.893,,62.94,HHH,-1.41,0.0495842,0.00356019,0.978851 beta-lactamase_39_A200Y,beta-lactamase_39_200,TEM-1,beta-lactamase_39,P62593,0.978854,NO,200,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.878,-4.399,2.521,,0.757,H,A,0.46,-0.19,1.54,,77.62,HHP,-2.001,0.0495842,0.0060056,0.978854 beta-lactamase_625_R63M,beta-lactamase_625_63,TEM-1,beta-lactamase_625,P62593,0.978856,NO,63,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-0.943,-4.402,3.459,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.213352,0.00126938,0.978856 beta-lactamase_2500_D271L,beta-lactamase_2500_271,TEM-1,beta-lactamase_2500,P62593,0.978867,NO,271,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.361275,0.00752082,0.978867 beta-lactamase_39_G236V,beta-lactamase_39_236,TEM-1,beta-lactamase_39,P62593,0.978872,NO,236,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.784,-3.686,2.902,,0.241,,b,0.29,-0.59,1.883,,64.69,HOO,-1.025,0.0495842,0.00162372,0.978872 beta-lactamase_39_L199E,beta-lactamase_39_199,TEM-1,beta-lactamase_39,P62593,0.978872,NO,199,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-2.942,-2.604,-0.338,,0.832,H,A,0.55,0.42,15.504,15.504,77.62,PHH,-2.32933,0.0495842,0.0048649,0.978872 beta-lactamase_156_L89Q,beta-lactamase_156_89,TEM-1,beta-lactamase_156,P62593,0.978876,NO,89,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.096,-4.086,2.99,,0.168,T,A,0.55,0.63,2.633,,64.34,PHO,-1.75767,0.111618,0.00207068,0.978876 beta-lactamase_625_P105H,beta-lactamase_625_105,TEM-1,beta-lactamase_625,P62593,0.978878,NO,105,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.813,-4.678,3.865,,0.226,T,A,0.52,0.8,1.154,,63.29,POH,-1.01533,0.213352,0.0011981,0.978878 gb1_D262W,gb1_262,gb1,gb1,P06654,0.978881,NO,262,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-3.132,-5.231,2.099,,,,,,,1.304,,45.54,PAP,-2.05233,0.177985,0.00413102,0.978881 gb1_K236E,gb1_236,gb1,gb1,P06654,0.978881,NO,236,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-2.119,-2.974,0.855,,,,,,,1.083,,45.54,OBP,-1.758,0.177985,0.00255408,0.978881 gb1_T277S,gb1_277,gb1,gb1,P06654,0.978881,NO,277,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.771,-2.236,0.465,,,,,,,0.824,,35.71,BPH,-1.54833,0.177985,0.00348258,0.978881 kka2_1:8_D62H,kka2_1:8_62,Kka2,kka2_1:8,P00552,0.978882,NO,62,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.591,-3.352,1.761,,0.262,H,A,0.29,0.08,5.58,,64.39,PAA,-1.77833,0.100394,0.00744243,0.978882 kka2_1:8_D62H,kka2_1:8_62,Kka2,kka2_1:8,P00552,0.978882,NO,62,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.591,-3.352,1.761,,0.262,H,A,0.29,0.08,5.58,,64.39,PAA,-1.77833,0.100394,0.00744243,0.978882 Pab1_I130M,Pab1_130,Pab1,Pab1,P04147,0.978883,NO,130,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.212,-3.847,2.635,,,E,B,1.23,0.01,,,,HHB,-1.188,0.175299,0.000351112,0.978883 beta-lactamase_625_E62A,beta-lactamase_625_62,TEM-1,beta-lactamase_625,P62593,0.978887,NO,62,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.193,-2.533,1.34,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.213352,0.00264802,0.978887 beta-lactamase_156_M153R,beta-lactamase_156_153,TEM-1,beta-lactamase_156,P62593,0.978897,NO,153,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-3.193,-4.075,0.882,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.111618,0.00509109,0.978897 beta-lactamase_625_N173F,beta-lactamase_625_173,TEM-1,beta-lactamase_625,P62593,0.978898,NO,173,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-2.663,-4.355,1.692,,1.044,T,l,0.61,1.25,1.426,,77.62,OPA,-1.46633,0.213352,0.0033769,0.978898 beta-lactamase_39_K30D,beta-lactamase_39_30,TEM-1,beta-lactamase_39,P62593,0.978911,NO,30,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-2.307,-3.567,1.26,,0.142,H,A,2.34,-0.65,6.717,,93.01,HBH,-2.32833,0.0495842,0.00448593,0.978911 beta-lactamase_625_T139L,beta-lactamase_625_139,TEM-1,beta-lactamase_625,P62593,0.978921,NO,139,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.901,-3.419,1.518,,0.216,H,A,0.22,0.39,2.256,,77.62,PPH,-2.04667,0.213352,0.00441837,0.978921 beta-lactamase_625_A170N,beta-lactamase_625_170,TEM-1,beta-lactamase_625,P62593,0.978925,NO,170,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.237,-2.833,1.596,,0.126,,L,0.46,-0.35,3.626,,64.69,AHH,-1.63267,0.213352,0.00431903,0.978925 beta-lactamase_625_D33Y,beta-lactamase_625_33,TEM-1,beta-lactamase_625,P62593,0.978926,NO,33,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.321,-4.331,2.01,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.213352,0.00435556,0.978926 kka2_1:4_A41I,kka2_1:4_41,Kka2,kka2_1:4,P00552,0.978932,NO,41,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.879,-3.958,2.079,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.168804,0.00543332,0.978932 kka2_1:8_I141S,kka2_1:8_141,Kka2,kka2_1:8,P00552,0.978934,NO,141,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.495,-3.763,2.268,,0.068,H,A,1.52,-0.01,2.144,,92.05,BHA,-1.689,0.100394,0.00744745,0.978934 kka2_1:8_I141S,kka2_1:8_141,Kka2,kka2_1:8,P00552,0.978934,NO,141,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.495,-3.763,2.268,,0.068,H,A,1.52,-0.01,2.144,,92.05,BHA,-1.689,0.100394,0.00744745,0.978934 kka2_1:8_I29F,kka2_1:8_29,Kka2,kka2_1:8,P00552,0.978934,NO,29,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.692,-4.042,2.35,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.100394,0.00619521,0.978934 kka2_1:8_I29F,kka2_1:8_29,Kka2,kka2_1:8,P00552,0.978934,NO,29,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.692,-4.042,2.35,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.100394,0.00619521,0.978934 beta-lactamase_156_G141E,beta-lactamase_156_141,TEM-1,beta-lactamase_156,P62593,0.978943,NO,141,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.828,-2.606,1.778,,0.575,T,l,0.29,-0.28,0.198,,64.69,HOO,-1.08933,0.111618,0.0012419,0.978943 beta-lactamase_A183E,beta-lactamase_183,TEM-1,beta-lactamase,P62593,0.978956,NO,183,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.231,-3.42,2.189,4.84712,0.155,H,A,0.55,-0.91,12.189,,77.62,HHH,-1.53367,0.221079,0.00296631,0.978956 beta-lactamase_625_R189Y,beta-lactamase_625_189,TEM-1,beta-lactamase_625,P62593,0.978962,NO,189,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.844,-3.134,1.29,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.213352,0.0050699,0.978962 kka2_1:4_Q219I,kka2_1:4_219,Kka2,kka2_1:4,P00552,0.978972,NO,219,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-0.93,-4.062,3.132,,0.088,H,A,0.64,-0.85,1.537,,50,HPA,-1.05167,0.168804,0.00237913,0.978972 beta-lactamase_0_K286N,beta-lactamase_0_286,TEM-1,beta-lactamase_0,P62593,0.978982,NO,286,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.0500837,,0.978982 beta-lactamase_625_V101G,beta-lactamase_625_101,TEM-1,beta-lactamase_625,P62593,0.978997,NO,101,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.295,-3.721,2.426,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.213352,0.00374492,0.978997 kka2_1:4_A110T,kka2_1:4_110,Kka2,kka2_1:4,P00552,0.978998,NO,110,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.064,-3.141,1.077,,0.175,H,A,0.46,-1.19,23.237,23.237,71.59,OHA,-1.91867,0.168804,0.00759851,0.978998 beta-lactamase_2500_T193D,beta-lactamase_2500_193,TEM-1,beta-lactamase_2500,P62593,0.979003,NO,193,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.914,-3.815,1.901,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.361275,0.00482669,0.979003 beta-lactamase_625_D252C,beta-lactamase_625_252,TEM-1,beta-lactamase_625,P62593,0.979007,NO,252,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.213352,0.00575769,0.979007 Pab1_V198C,Pab1_198,Pab1,Pab1,P04147,0.979017,NO,198,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.113,-4.454,3.341,,0.008,E,B,0.61,0.91,,,,HHH,-1.32933,0.175299,0.000268557,0.979017 beta-lactamase_39_I45R,beta-lactamase_39_45,TEM-1,beta-lactamase_39,P62593,0.979021,NO,45,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-2.421,-4.043,1.622,,,E,B,0.48,-0.3,2.256,,77.62,HHA,-2.30267,0.0495842,0.00452842,0.979021 beta-lactamase_156_D48E,beta-lactamase_156_48,TEM-1,beta-lactamase_156,P62593,0.979029,NO,48,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.101,-2.049,0.948,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.111618,0.0027273,0.979029 beta-lactamase_2500_E175I,beta-lactamase_2500_175,TEM-1,beta-lactamase_2500,P62593,0.979031,NO,175,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.336,-3.797,1.461,,0.551,,A,1.04,1.05,5.316,,77.62,AAB,-1.31233,0.361275,0.00482205,0.979031 Pab1_K164S,Pab1_164,Pab1,Pab1,P04147,0.979031,NO,164,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-2.298,-2.544,0.246,,,,,,,,,,OBP,-1.41767,0.175299,0.00255241,0.979031 beta-lactamase_156_G76Y,beta-lactamase_156_76,TEM-1,beta-lactamase_156,P62593,0.979044,NO,76,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.189,-4.36,3.171,,,H,A,0.29,-0.67,3.059,,67.83,OOH,-1.22267,0.111618,0.00476637,0.979044 Pab1_N162I,Pab1_162,Pab1,Pab1,P04147,0.979045,NO,162,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-2.313,-3.659,1.346,,0.681,T,A,,1.12,,,,APO,-1.532,0.175299,0.0030719,0.979045 beta-lactamase_625_M153E,beta-lactamase_625_153,TEM-1,beta-lactamase_625,P62593,0.979048,NO,153,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-3.193,-3.818,0.625,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.213352,0.00509109,0.979048 kka2_1:8_L152V,kka2_1:8_152,Kka2,kka2_1:8,P00552,0.979057,NO,152,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.521,-2.421,0.9,,0.547,.,A,0.55,1.36,1.442,,63.64,OHH,-1.162,0.100394,0.00674868,0.979057 kka2_1:8_L152V,kka2_1:8_152,Kka2,kka2_1:8,P00552,0.979057,NO,152,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.521,-2.421,0.9,,0.547,.,A,0.55,1.36,1.442,,63.64,OHH,-1.162,0.100394,0.00674868,0.979057 Pab1_K164E,Pab1_164,Pab1,Pab1,P04147,0.979061,NO,164,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-2.298,-3.244,0.946,,,,,,,,,,OBP,-1.41767,0.175299,0.00255241,0.979061 beta-lactamase_39_L137C,beta-lactamase_39_137,TEM-1,beta-lactamase_39,P62593,0.979066,NO,137,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.03,-4.702,3.672,,,H,A,0.55,-0.38,0.674,,42.31,HHP,-1.58933,0.0495842,0.00278599,0.979066 beta-lactamase_625_S57C,beta-lactamase_625_57,TEM-1,beta-lactamase_625,P62593,0.979068,NO,57,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.918,-4.926,3.008,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.213352,0.00492804,0.979068 beta-lactamase_156_S57C,beta-lactamase_156_57,TEM-1,beta-lactamase_156,P62593,0.979069,NO,57,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.918,-4.926,3.008,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.111618,0.00492804,0.979069 beta-lactamase_A84C,beta-lactamase_84,TEM-1,beta-lactamase,P62593,0.97907,NO,84,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.651,-5.003,3.352,5.28927,0.65,T,A,0.52,0.96,1.863,,68.18,AHO,-1.24267,0.221079,0.00503822,0.97907 beta-lactamase_S221M,beta-lactamase_221,TEM-1,beta-lactamase,P62593,0.97907,NO,221,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.754,-4.595,2.841,5.77407,0.624,H,A,0.74,-0.2,0.383,,74.48,BPH,-1.59967,0.221079,0.0046094,0.97907 beta-lactamase_T126C,beta-lactamase_126,TEM-1,beta-lactamase,P62593,0.97907,NO,126,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.122,-4.816,3.694,4.82694,0.05,H,A,0.3,-0.05,1.14,,44.41,HPH,-1.60467,0.221079,0.00244552,0.97907 beta-lactamase_V101V,beta-lactamase_101,TEM-1,beta-lactamase,P62593,0.97907,NO,101,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.295,-1.295,,5.49045,0.342,,B,0.96,0,1.675,,73.08,HHA,-1.54367,0.221079,0.00374492,0.97907 beta-lactamase_39_L73D,beta-lactamase_39_73,TEM-1,beta-lactamase_39,P62593,0.979084,NO,73,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.507,-4.091,2.584,,,H,A,0.55,-0.64,2.09,,67.83,HHH,-1.487,0.0495842,0.00488983,0.979084 kka2_1:2_L94T,kka2_1:2_94,Kka2,kka2_1:2,P00552,0.979089,NO,94,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.618,-2.787,1.169,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.295029,0.00520888,0.979089 beta-lactamase_39_V260A,beta-lactamase_39_260,TEM-1,beta-lactamase_39,P62593,0.979092,NO,260,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.0495842,0.00471757,0.979092 Pab1_S165A,Pab1_165,Pab1,Pab1,P04147,0.979095,NO,165,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.146,-2.445,1.299,,0.12,,a,,0.11,,,,BPB,-1.56867,0.175299,0.000307838,0.979095 beta-lactamase_156_K190F,beta-lactamase_156_190,TEM-1,beta-lactamase_156,P62593,0.979112,NO,190,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.994,-4.396,2.402,,0.371,H,A,2.34,0.16,1.513,,77.62,BBH,-1.64167,0.111618,0.00574527,0.979112 beta-lactamase_39_R242W,beta-lactamase_39_242,TEM-1,beta-lactamase_39,P62593,0.979132,NO,242,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.0495842,0.00452879,0.979132 beta-lactamase_625_T147N,beta-lactamase_625_147,TEM-1,beta-lactamase_625,P62593,0.979134,NO,147,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.149,-2.415,1.266,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.213352,0.00226017,0.979134 beta-lactamase_2500_T138V,beta-lactamase_2500_138,TEM-1,beta-lactamase_2500,P62593,0.979141,NO,138,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.506,-3.689,1.183,,0.662,H,A,0.22,-0.03,30.445,30.445,73.78,HPP,-1.81233,0.361275,0.00487868,0.979141 beta-lactamase_2500_T193N,beta-lactamase_2500_193,TEM-1,beta-lactamase_2500,P62593,0.979142,NO,193,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.914,-2.715,0.801,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.361275,0.00482669,0.979142 beta-lactamase_625_N98W,beta-lactamase_625_98,TEM-1,beta-lactamase_625,P62593,0.979142,NO,98,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-2.973,-5.455,2.482,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.213352,0.00505389,0.979142 PSD95pdz3_D357F,PSD95pdz3_357,PSD95pdz3,PSD95pdz3,P31016,0.979143,NO,357,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.264,-3.974,2.71,5.22306,,,,,10.975,,,,OAP,-1.32367,0.0758425,0.000609015,0.979143 beta-lactamase_156_A200D,beta-lactamase_156_200,TEM-1,beta-lactamase_156,P62593,0.979165,NO,200,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.878,-2.929,1.051,,0.757,H,A,0.46,-0.19,16.368,16.368,77.62,HHP,-2.001,0.111618,0.0060056,0.979165 beta-lactamase_39_I125Q,beta-lactamase_39_125,TEM-1,beta-lactamase_39,P62593,0.979175,NO,125,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.441,-4.226,2.785,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.0495842,0.00383964,0.979175 beta-lactamase_2500_S122K,beta-lactamase_2500_122,TEM-1,beta-lactamase_2500,P62593,0.979177,NO,122,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.406,-3.55,1.144,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.361275,0.00497825,0.979177 beta-lactamase_39_T116P,beta-lactamase_39_116,TEM-1,beta-lactamase_39,P62593,0.979177,NO,116,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.28,-3.831,2.551,,0.115,E,B,0.22,-0.12,1.133,,67.48,HPH,-1.39967,0.0495842,0.00336175,0.979177 Pab1_D151H,Pab1_151,Pab1,Pab1,P04147,0.97918,NO,151,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.399,-4.304,1.905,,,,,,,,,,OAH,-1.51767,0.175299,0.00228155,0.97918 beta-lactamase_2500_K53S,beta-lactamase_2500_53,TEM-1,beta-lactamase_2500,P62593,0.979189,NO,53,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-2.313,-2.879,0.566,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.361275,0.00383383,0.979189 beta-lactamase_2500_A225S,beta-lactamase_2500_225,TEM-1,beta-lactamase_2500,P62593,0.979197,NO,225,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.845,-2.863,1.018,,1,T,B,0.46,-0.38,0.551,,74.48,OHO,-1.39967,0.361275,0.00465057,0.979197 beta-lactamase_39_D33S,beta-lactamase_39_33,TEM-1,beta-lactamase_39,P62593,0.979198,NO,33,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.321,-2.627,0.306,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.0495842,0.00435556,0.979198 beta-lactamase_39_Q37C,beta-lactamase_39_37,TEM-1,beta-lactamase_39,P62593,0.979206,NO,37,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.134,-5.133,2.999,,0.613,H,A,0.64,1.98,22.282,22.282,73.08,APH,-2.06967,0.0495842,0.00425833,0.979206 beta-lactamase_2500_E175H,beta-lactamase_2500_175,TEM-1,beta-lactamase_2500,P62593,0.979209,NO,175,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.336,-3.355,1.019,,0.551,,A,1.04,1.05,5.316,,77.62,AAB,-1.31233,0.361275,0.00482205,0.979209 beta-lactamase_156_R81N,beta-lactamase_156_81,TEM-1,beta-lactamase_156,P62593,0.979213,NO,81,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.466,-2.825,1.359,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.111618,0.00499763,0.979213 kka2_1:8_A229G,kka2_1:8_229,Kka2,kka2_1:8,P00552,0.979215,NO,229,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.739,-2.492,0.753,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.100394,0.00942138,0.979215 kka2_1:8_A229G,kka2_1:8_229,Kka2,kka2_1:8,P00552,0.979215,NO,229,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.739,-2.492,0.753,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.100394,0.00942138,0.979215 beta-lactamase_39_D113T,beta-lactamase_39_113,TEM-1,beta-lactamase_39,P62593,0.979216,NO,113,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.829,-2.544,0.715,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.0495842,0.00474112,0.979216 beta-lactamase_156_D207Q,beta-lactamase_156_207,TEM-1,beta-lactamase_156,P62593,0.979222,NO,207,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.064,-2.209,0.145,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.111618,0.00592942,0.979222 beta-lactamase_625_G90N,beta-lactamase_625_90,TEM-1,beta-lactamase_625,P62593,0.979223,NO,90,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-2.091,-2.941,0.85,,0.598,T,A,0.29,0.32,0.319,,77.62,HOB,-1.52633,0.213352,0.00490273,0.979223 beta-lactamase_156_S266F,beta-lactamase_156_266,TEM-1,beta-lactamase_156,P62593,0.979224,NO,266,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.111618,0.0140785,0.979224 beta-lactamase_39_L74E,beta-lactamase_39_74,TEM-1,beta-lactamase_39,P62593,0.979227,NO,74,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.296,-3.786,2.49,,,H,A,0.55,-0.91,1.581,,50,HHO,-1.34933,0.0495842,0.00493255,0.979227 beta-lactamase_39_D99A,beta-lactamase_39_99,TEM-1,beta-lactamase_39,P62593,0.979228,NO,99,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.191,-2.613,1.422,,0.402,G,A,0.75,0.36,0.374,,64.69,PAH,-1.794,0.0495842,0.00305446,0.979228 beta-lactamase_156_W288F,beta-lactamase_156_288,TEM-1,beta-lactamase_156,P62593,0.979229,NO,288,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,,,,,,,,,,,,,BHO,,0.111618,,0.979229 PSD95pdz3_E352W,PSD95pdz3_352,PSD95pdz3,PSD95pdz3,P31016,0.979232,NO,352,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.587,-5.099,3.512,5.49659,,,,,24.2,2.525,,86.88,OAH,-1.314,0.0758425,0.000892231,0.979232 beta-lactamase_39_E102D,beta-lactamase_39_102,TEM-1,beta-lactamase_39,P62593,0.979245,NO,102,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.118,-2.118,0,,0.722,S,B,1.04,1.82,3.87,,73.08,HAH,-1.581,0.0495842,0.00486633,0.979245 beta-lactamase_625_V214S,beta-lactamase_625_214,TEM-1,beta-lactamase_625,P62593,0.979252,NO,214,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.299,-3.408,2.109,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.213352,0.00628442,0.979252 kka2_1:2_V198A,kka2_1:2_198,Kka2,kka2_1:2,P00552,0.979255,NO,198,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.719,-1.379,-0.34,,0.05,E,B,1.48,-0.95,1.074,,56.06,HHA,-1.88667,0.295029,0.00835002,0.979255 beta-lactamase_39_E56G,beta-lactamase_39_56,TEM-1,beta-lactamase_39,P62593,0.979257,NO,56,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.043,-2.304,0.261,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.0495842,0.00238534,0.979257 beta-lactamase_2500_P60I,beta-lactamase_2500_60,TEM-1,beta-lactamase_2500,P62593,0.979263,NO,60,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-2.469,-3.895,1.426,,0.256,T,A,0.52,-0.56,1.581,,77.62,BOA,-1.97633,0.361275,0.00521318,0.979263 kka2_1:8_A108E,kka2_1:8_108,Kka2,kka2_1:8,P00552,0.979267,NO,108,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.061,-2.517,0.456,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.100394,0.00751209,0.979267 kka2_1:8_A108E,kka2_1:8_108,Kka2,kka2_1:8,P00552,0.979267,NO,108,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.061,-2.517,0.456,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.100394,0.00751209,0.979267 beta-lactamase_K32L,beta-lactamase_32,TEM-1,beta-lactamase,P62593,0.979269,NO,32,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.984,-2.812,0.828,5.55842,0.563,H,A,1.82,0.34,1.754,,73.08,HBA,-2.04233,0.221079,0.00401283,0.979269 beta-lactamase_L167C,beta-lactamase_167,TEM-1,beta-lactamase,P62593,0.979269,NO,167,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.138,-4.763,3.625,5.13111,0.015,G,A,0.08,-0.63,0.4,,64.69,AHP,-1.30767,0.221079,0.00303566,0.979269 beta-lactamase_T262S,beta-lactamase_262,TEM-1,beta-lactamase,P62593,0.979269,NO,262,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.332,-2.306,0.974,5.06002,0.108,E,B,0.3,-0.55,1.423,,67.83,PPO,-2.081,0.221079,0.00853516,0.979269 beta-lactamase_156_Q204F,beta-lactamase_156_204,TEM-1,beta-lactamase_156,P62593,0.979271,NO,204,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-1.382,-4.303,2.921,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.111618,0.00364106,0.979271 beta-lactamase_39_Y95C,beta-lactamase_39_95,TEM-1,beta-lactamase_39,P62593,0.979287,NO,95,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-1.715,-4.95,3.235,,0.122,,b,0.21,-0.37,2.341,,77.62,BHP,-2.16167,0.0495842,0.00479449,0.979287 beta-lactamase_2500_T263F,beta-lactamase_2500_263,TEM-1,beta-lactamase_2500,P62593,0.979292,NO,263,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.361275,0.0110582,0.979292 beta-lactamase_0_T158H,beta-lactamase_0_158,TEM-1,beta-lactamase_0,P62593,0.979294,NO,158,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.116,-4.689,3.573,,0.036,,B,0.22,-0.85,1.041,,69.58,HPB,-1.269,0.0500837,0.00341825,0.979294 kka2_1:2_E160K,kka2_1:2_160,Kka2,kka2_1:2,P00552,0.979301,NO,160,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.683,-2.805,1.122,,0.989,G,A,1.04,2.28,3.948,,71.59,AAA,-1.36133,0.295029,0.00935762,0.979301 beta-lactamase_39_D36G,beta-lactamase_39_36,TEM-1,beta-lactamase_39,P62593,0.979303,NO,36,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.732,-2.829,0.097,,0.555,H,A,0.75,1.17,13.689,13.689,77.62,AAP,-1.91167,0.0495842,0.00476483,0.979303 beta-lactamase_625_A222V,beta-lactamase_625_222,TEM-1,beta-lactamase_625,P62593,0.979309,NO,222,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.103,-1.973,-0.13,,0.233,H,A,0.46,-0.25,1.448,,77.62,PHH,-1.63733,0.213352,0.00466094,0.979309 beta-lactamase_Q203I,beta-lactamase_203,TEM-1,beta-lactamase,P62593,0.97932,NO,203,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.168,-3.973,1.805,5.65296,0.47,H,A,0.12,-0.38,1.66,,65.38,BPP,-1.614,0.221079,0.00631514,0.97932 beta-lactamase_156_M153N,beta-lactamase_156_153,TEM-1,beta-lactamase_156,P62593,0.979322,NO,153,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-3.193,-3.994,0.801,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.111618,0.00509109,0.979322 beta-lactamase_2500_D36I,beta-lactamase_2500_36,TEM-1,beta-lactamase_2500,P62593,0.979322,NO,36,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.732,-4.112,1.38,,0.555,H,A,0.75,1.17,2.26,,77.62,AAP,-1.91167,0.361275,0.00476483,0.979322 beta-lactamase_39_D99Y,beta-lactamase_39_99,TEM-1,beta-lactamase_39,P62593,0.979323,NO,99,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.191,-4.234,3.043,,0.402,G,A,0.75,0.36,0.374,,64.69,PAH,-1.794,0.0495842,0.00305446,0.979323 beta-lactamase_625_L111A,beta-lactamase_625_111,TEM-1,beta-lactamase_625,P62593,0.979349,NO,111,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.76,-2.229,0.469,,0.328,T,A,0.55,0.93,2.26,,64.34,BHP,-1.884,0.213352,0.00480671,0.979349 hsp90_Q582S,hsp90_582,hsp90,hsp90,P02829,0.979352,NO,582,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-3.278,-2.764,0,4.91603,0.453,S,B,,0.67,,,,OPH,-3.249,0.368192,0.000222939,0.979352 beta-lactamase_39_D161T,beta-lactamase_39_161,TEM-1,beta-lactamase_39,P62593,0.979355,NO,161,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.891,-3.414,2.523,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.0495842,0.000897697,0.979355 beta-lactamase_Q86N,beta-lactamase_86,TEM-1,beta-lactamase,P62593,0.979357,NO,86,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.4,-3.754,1.354,5.39897,0.696,S,A,0.12,2.38,2.105,,77.62,OPA,-1.61067,0.221079,0.00450027,0.979357 beta-lactamase_156_L146G,beta-lactamase_156_146,TEM-1,beta-lactamase_156,P62593,0.97936,NO,146,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.462,-3.742,2.28,,0.007,H,A,0.55,-0.56,1.578,,64.69,AHP,-1.656,0.111618,0.00474542,0.97936 beta-lactamase_156_G281I,beta-lactamase_156_281,TEM-1,beta-lactamase_156,P62593,0.979365,NO,281,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.111618,0.0406482,0.979365 kka2_1:4_M178I,kka2_1:4_178,Kka2,kka2_1:4,P00552,0.979366,NO,178,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-3.206,-2.948,-0.258,,0.554,.,b,0.55,0.68,9.913,9.913,71.59,BHO,-2.154,0.168804,0.00717253,0.979366 beta-lactamase_156_T263F,beta-lactamase_156_263,TEM-1,beta-lactamase_156,P62593,0.979367,NO,263,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.111618,0.0110582,0.979367 beta-lactamase_625_L160C,beta-lactamase_625_160,TEM-1,beta-lactamase_625,P62593,0.979369,NO,160,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.977,-4.68,3.703,,0.022,,B,0.55,-0.6,0.237,,44.41,BHA,-0.936,0.213352,0.00193775,0.979369 beta-lactamase_39_R189S,beta-lactamase_39_189,TEM-1,beta-lactamase_39,P62593,0.979387,NO,189,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.844,-2.849,1.005,,0.278,H,A,1.2,1.01,12.11,12.11,72.73,HBB,-1.668,0.0495842,0.0050699,0.979387 beta-lactamase_156_L197M,beta-lactamase_156_197,TEM-1,beta-lactamase_156,P62593,0.97939,NO,197,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.853,-3.888,3.035,,0.007,S,B,0.55,0.33,1.58,,60.14,HHP,-1.833,0.111618,0.00144602,0.97939 beta-lactamase_39_Y44A,beta-lactamase_39_44,TEM-1,beta-lactamase_39,P62593,0.979391,NO,44,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-2.547,-2.301,-0.246,,,E,B,0.21,-0.45,2.683,,73.78,OHH,-1.86267,0.0495842,0.00426364,0.979391 beta-lactamase_156_D36Y,beta-lactamase_156_36,TEM-1,beta-lactamase_156,P62593,0.979396,NO,36,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.732,-3.266,0.534,,0.555,H,A,0.75,1.17,14.871,14.871,77.62,AAP,-1.91167,0.111618,0.00476483,0.979396 beta-lactamase_156_P165N,beta-lactamase_156_165,TEM-1,beta-lactamase_156,P62593,0.979407,NO,165,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.373,-3.703,2.33,,0.203,T,A,0.52,-0.31,3.907,,73.78,AOA,-1.359,0.111618,0.00549538,0.979407 beta-lactamase_M127Q,beta-lactamase_127,TEM-1,beta-lactamase,P62593,0.979407,NO,127,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-2.251,-2.96,0.709,5.40552,0.312,S,A,1.07,0.32,1.671,,72.73,PHP,-1.40433,0.221079,0.00437927,0.979407 beta-lactamase_M153V,beta-lactamase_153,TEM-1,beta-lactamase,P62593,0.979407,NO,153,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-3.193,-2.524,-0.669,5.46509,0.14,T,A,1.07,-0.11,2.061,,77.62,PHO,-2.25767,0.221079,0.00509109,0.979407 beta-lactamase_Q265P,beta-lactamase_265,TEM-1,beta-lactamase,P62593,0.979407,NO,265,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.58,-2.505,-0.075,6.62674,1.116,,A,0.03,1.17,12.514,12.514,69.58,PPH,-1.978,0.221079,0.00811926,0.979407 beta-lactamase_39_G90L,beta-lactamase_39_90,TEM-1,beta-lactamase_39,P62593,0.979409,NO,90,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-2.091,-3.689,1.598,,0.598,T,A,0.29,0.32,30.794,30.794,77.62,HOB,-1.52633,0.0495842,0.00490273,0.979409 beta-lactamase_39_G216Q,beta-lactamase_39_216,TEM-1,beta-lactamase_39,P62593,0.97941,NO,216,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.477,-3.862,2.385,,0.437,I,A,0.29,-0.58,0.834,,74.48,HOO,-1.68067,0.0495842,0.00639568,0.97941 beta-lactamase_39_Y103N,beta-lactamase_39_103,TEM-1,beta-lactamase_39,P62593,0.979411,NO,103,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-1.33,-2.825,1.495,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.0495842,0.00443048,0.979411 beta-lactamase_156_L49C,beta-lactamase_156_49,TEM-1,beta-lactamase_156,P62593,0.979412,NO,49,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.897,-4.929,3.032,,0.131,T,A,0.55,0.04,3.112,,64.69,AHP,-1.99233,0.111618,0.00401477,0.979412 beta-lactamase_A222G,beta-lactamase_222,TEM-1,beta-lactamase,P62593,0.979417,NO,222,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.103,-1.732,-0.371,5.2262,0.233,H,A,0.47,-0.25,0.379,,77.62,PHH,-1.63733,0.221079,0.00466094,0.979417 beta-lactamase_G251S,beta-lactamase_251,TEM-1,beta-lactamase,P62593,0.979427,NO,251,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.907,-2.667,0.76,5.33865,0.506,T,l,0.73,0.17,10.663,,65.38,AOB,-2.06067,0.221079,0.00733416,0.979427 beta-lactamase_625_G154K,beta-lactamase_625_154,TEM-1,beta-lactamase_625,P62593,0.979428,NO,154,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.823,-3.683,2.86,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.213352,0.00180205,0.979428 beta-lactamase_0_P65V,beta-lactamase_0_65,TEM-1,beta-lactamase_0,P62593,0.979431,NO,65,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.894,-3.39,2.496,,0.098,E,B,0.52,-0.62,0.663,,40.56,HOH,-1.03233,0.0500837,0.00152776,0.979431 beta-lactamase_39_S283I,beta-lactamase_39_283,TEM-1,beta-lactamase_39,P62593,0.979442,NO,283,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.638,-3.539,1.901,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.0495842,0.0429138,0.979442 beta-lactamase_2500_K254I,beta-lactamase_2500_254,TEM-1,beta-lactamase_2500,P62593,0.979443,NO,254,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.361275,0.00369,0.979443 beta-lactamase_A280T,beta-lactamase_280,TEM-1,beta-lactamase,P62593,0.97945,NO,280,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.708,-3.522,1.814,4.74932,0.379,H,A,0.52,-0.72,1.785,,68.18,OHP,-1.66433,0.221079,0.0530888,0.97945 beta-lactamase_V8A,beta-lactamase_8,TEM-1,beta-lactamase,P62593,0.97945,NO,8,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-2.358,-3.025,0.667,,,,,,,0.575,,77.62,BHH,-2.06267,0.221079,0.00226401,0.97945 beta-lactamase_39_W288K,beta-lactamase_39_288,TEM-1,beta-lactamase_39,P62593,0.979453,NO,288,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,,,,,,,,,,,,,BHO,,0.0495842,,0.979453 beta-lactamase_39_H287F,beta-lactamase_39_287,TEM-1,beta-lactamase_39,P62593,0.979467,NO,287,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,,,,,,,,,,,,,BBH,-1.111,0.0495842,,0.979467 beta-lactamase_39_D161G,beta-lactamase_39_161,TEM-1,beta-lactamase_39,P62593,0.97947,NO,161,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.891,-3.177,2.286,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.0495842,0.000897697,0.97947 beta-lactamase_39_G216E,beta-lactamase_39_216,TEM-1,beta-lactamase_39,P62593,0.979474,NO,216,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.477,-2.451,0.974,,0.437,I,A,0.29,-0.58,0.834,,74.48,HOO,-1.68067,0.0495842,0.00639568,0.979474 beta-lactamase_156_L120T,beta-lactamase_156_120,TEM-1,beta-lactamase_156,P62593,0.979475,NO,120,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.044,-3.547,2.503,,,H,A,0.55,-1.13,7.813,,64.69,AHO,-1.13633,0.111618,0.00143563,0.979475 beta-lactamase_E166A,beta-lactamase_166,TEM-1,beta-lactamase,P62593,0.979477,NO,166,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.756,-2.056,0.3,5.60527,0.508,G,A,0.52,1.05,2.124,,73.08,OAH,-1.42233,0.221079,0.00512989,0.979477 beta-lactamase_0_R189Y,beta-lactamase_0_189,TEM-1,beta-lactamase_0,P62593,0.979485,NO,189,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.844,-3.134,1.29,,0.278,H,A,1.2,1.01,12.11,12.11,72.73,HBB,-1.668,0.0500837,0.0050699,0.979485 beta-lactamase_2500_E166N,beta-lactamase_2500_166,TEM-1,beta-lactamase_2500,P62593,0.979485,NO,166,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.756,-3.709,1.953,,0.508,G,A,1.04,1.05,2.124,,73.08,OAH,-1.42233,0.361275,0.00512989,0.979485 beta-lactamase_39_W288V,beta-lactamase_39_288,TEM-1,beta-lactamase_39,P62593,0.979487,NO,288,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,,,,,,,,,,,,,BHO,,0.0495842,,0.979487 beta-lactamase_2500_W163M,beta-lactamase_2500_163,TEM-1,beta-lactamase_2500,P62593,0.979495,NO,163,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-1.843,-3.104,1.261,,0.467,,B,0.47,-0.5,32.624,32.624,63.99,BHA,-1.269,0.361275,0.00418955,0.979495 beta-lactamase_156_N134A,beta-lactamase_156_134,TEM-1,beta-lactamase_156,P62593,0.979503,NO,134,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-0.879,-3.3,2.421,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.111618,0.000644786,0.979503 beta-lactamase_39_V31L,beta-lactamase_39_31,TEM-1,beta-lactamase_39,P62593,0.979503,NO,31,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.822,-2.16,0.338,,,H,A,0.44,-0.46,2.885,,73.78,BHB,-2.03767,0.0495842,0.00478065,0.979503 beta-lactamase_156_P255L,beta-lactamase_156_255,TEM-1,beta-lactamase_156,P62593,0.979504,NO,255,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.111618,0.00499612,0.979504 beta-lactamase_K213N,beta-lactamase_213,TEM-1,beta-lactamase,P62593,0.979517,NO,213,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.81,-3.623,1.813,5.63167,0.67,,A,1.59,0.29,3.924,,67.83,ABH,-1.57767,0.221079,0.00610411,0.979517 beta-lactamase_156_R176M,beta-lactamase_156_176,TEM-1,beta-lactamase_156,P62593,0.979518,NO,176,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-0.863,-4.48,3.617,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.111618,0.00105554,0.979518 beta-lactamase_2500_A278H,beta-lactamase_2500_278,TEM-1,beta-lactamase_2500,P62593,0.979518,NO,278,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.361275,0.0310297,0.979518 beta-lactamase_625_S256L,beta-lactamase_625_256,TEM-1,beta-lactamase_625,P62593,0.979519,NO,256,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.213352,0.00710634,0.979519 beta-lactamase_156_E102T,beta-lactamase_156_102,TEM-1,beta-lactamase_156,P62593,0.97952,NO,102,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.118,-2.156,0.038,,0.722,S,B,1.04,1.82,15.721,15.721,73.08,HAH,-1.581,0.111618,0.00486633,0.97952 beta-lactamase_156_G114K,beta-lactamase_156_114,TEM-1,beta-lactamase_156,P62593,0.979524,NO,114,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.094,-3.566,2.472,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.111618,0.00224919,0.979524 beta-lactamase_2500_H156A,beta-lactamase_2500_156,TEM-1,beta-lactamase_2500,P62593,0.979533,NO,156,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-3.156,-2.83,-0.326,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.361275,0.00468596,0.979533 beta-lactamase_156_D207Y,beta-lactamase_156_207,TEM-1,beta-lactamase_156,P62593,0.979541,NO,207,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.064,-4.317,2.253,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.111618,0.00592942,0.979541 beta-lactamase_625_L146W,beta-lactamase_625_146,TEM-1,beta-lactamase_625,P62593,0.97955,NO,146,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.462,-2.894,1.432,,0.007,H,A,0.55,-0.56,2.16,,64.69,AHP,-1.656,0.213352,0.00474542,0.97955 beta-lactamase_625_A278E,beta-lactamase_625_278,TEM-1,beta-lactamase_625,P62593,0.979561,NO,278,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.213352,0.0310297,0.979561 PSD95pdz3_D332E,PSD95pdz3_332,PSD95pdz3,PSD95pdz3,P31016,0.979577,NO,332,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.264,-2.447,1.183,6.09878,,,,,48.762,,,,AAO,-1.22533,0.0758425,0.000937818,0.979577 beta-lactamase_39_D271F,beta-lactamase_39_271,TEM-1,beta-lactamase_39,P62593,0.979581,NO,271,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.0495842,0.00752082,0.979581 beta-lactamase_H151S,beta-lactamase_151,TEM-1,beta-lactamase,P62593,0.979584,NO,151,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-2.96,-2.636,-0.324,5.47408,0.594,H,A,0.35,0.1,1.843,,77.62,HBP,-2.34767,0.221079,0.00216946,0.979584 beta-lactamase_I54E,beta-lactamase_54,TEM-1,beta-lactamase,P62593,0.979584,NO,54,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-2.838,-2.58,-0.258,5.40541,0.669,E,B,0.77,-0.14,3.946,,73.78,BHH,-2.337,0.221079,0.00403589,0.979584 beta-lactamase_I54M,beta-lactamase_54,TEM-1,beta-lactamase,P62593,0.979584,NO,54,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-2.838,-3.13,0.292,5.40541,0.669,E,B,0.77,-0.14,3.946,,73.78,BHH,-2.337,0.221079,0.00403589,0.979584 beta-lactamase_39_T116I,beta-lactamase_39_116,TEM-1,beta-lactamase_39,P62593,0.979589,NO,116,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.28,-3.822,2.542,,0.115,E,B,0.22,-0.12,1.133,,67.48,HPH,-1.39967,0.0495842,0.00336175,0.979589 beta-lactamase_39_S104N,beta-lactamase_39_104,TEM-1,beta-lactamase_39,P62593,0.979598,NO,104,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.015,-3.421,2.406,,0.04,,b,0.27,0.57,4.02,,63.29,HPO,-1.05267,0.0495842,0.00218083,0.979598 beta-lactamase_2500_V157K,beta-lactamase_2500_157,TEM-1,beta-lactamase_2500,P62593,0.979599,NO,157,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.751,-2.698,0.947,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.361275,0.00506849,0.979599 kka2_1:4_C31W,kka2_1:4_31,Kka2,kka2_1:4,P00552,0.979599,NO,31,C,W,CW,Special,Hydrophobic,5.07,5.89,0.82,215,121,204,83,108.5,227.8,119.3,-2.246,-5.453,3.207,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.168804,0.00681582,0.979599 beta-lactamase_0_D129M,beta-lactamase_0_129,TEM-1,beta-lactamase_0,P62593,0.979605,NO,129,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.816,-4.927,4.111,,,,B,0.75,-0.69,2.66,,34.97,PAP,-0.818,0.0500837,0.00109178,0.979605 beta-lactamase_0_A278F,beta-lactamase_0_278,TEM-1,beta-lactamase_0,P62593,0.97962,NO,278,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.348,,,,0.015,H,A,0.48,-0.85,4.624,,63.29,HHA,-1.41833,0.0500837,0.0310297,0.97962 beta-lactamase_156_R63Q,beta-lactamase_156_63,TEM-1,beta-lactamase_156,P62593,0.979622,NO,63,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-0.943,-3.532,2.589,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.111618,0.00126938,0.979622 PSD95pdz3_S339H,PSD95pdz3_339,PSD95pdz3,PSD95pdz3,P31016,0.979622,NO,339,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.519,-4.137,2.618,5.34493,,,,,12.2167,,,,HPH,-1.55767,0.0758425,0.00084982,0.979622 beta-lactamase_156_D161Q,beta-lactamase_156_161,TEM-1,beta-lactamase_156,P62593,0.979623,NO,161,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.891,-3.667,2.776,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.111618,0.000897697,0.979623 Pab1_E176T,Pab1_176,Pab1,Pab1,P04147,0.979627,NO,176,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.003,-3.36,1.357,,,,,,,,,,AAO,-2.09933,0.175299,0.00264426,0.979627 beta-lactamase_625_N152E,beta-lactamase_625_152,TEM-1,beta-lactamase_625,P62593,0.979645,NO,152,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-2.757,-2.679,-0.078,,0.863,H,A,0.61,0.92,2.061,,77.62,BPH,-2.97,0.213352,0.00471429,0.979645 beta-lactamase_2500_D36F,beta-lactamase_2500_36,TEM-1,beta-lactamase_2500,P62593,0.979647,NO,36,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.732,-4.318,1.586,,0.555,H,A,0.75,1.17,2.26,,77.62,AAP,-1.91167,0.361275,0.00476483,0.979647 beta-lactamase_2500_E102H,beta-lactamase_2500_102,TEM-1,beta-lactamase_2500,P62593,0.979647,NO,102,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.118,-3.309,1.191,,0.722,S,B,1.04,1.82,1.336,,73.08,HAH,-1.581,0.361275,0.00486633,0.979647 beta-lactamase_156_N130C,beta-lactamase_156_130,TEM-1,beta-lactamase_156,P62593,0.979653,NO,130,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-0.798,-5.087,4.289,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.111618,0.000683376,0.979653 Pab1_N162C,Pab1_162,Pab1,Pab1,P04147,0.979654,NO,162,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-2.313,-4.933,2.62,,0.681,T,A,,1.12,,,,APO,-1.532,0.175299,0.0030719,0.979654 beta-lactamase_39_L111R,beta-lactamase_39_111,TEM-1,beta-lactamase_39,P62593,0.979655,NO,111,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.76,-4.077,2.317,,0.328,T,A,0.55,0.93,4.334,,64.34,BHP,-1.884,0.0495842,0.00480671,0.979655 beta-lactamase_625_V42L,beta-lactamase_625_42,TEM-1,beta-lactamase_625,P62593,0.97966,NO,42,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.564,-1.709,0.145,,0.017,E,B,0.44,-0.51,2.576,,63.99,BHO,-1.042,0.213352,0.00404515,0.97966 E1_Ubiquitin_H70A,E1_Ubiquitin_70,Uba1,E1_Ubiquitin,P0CG63,0.979664,NO,70,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-1.36,,,,0.05,E,B,0.61,-0.97,,,93.18,HBH,-1.146,0.18783,0.00206914,0.979664 E1_Ubiquitin_L73T,E1_Ubiquitin_73,Uba1,E1_Ubiquitin,P0CG63,0.979664,NO,73,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.039,-3.239,2.2,,0.518,,B,1.3,1,,,,BHB,-1.175,0.18783,0.00111236,0.979664 E1_Ubiquitin_Q41E,E1_Ubiquitin_41,Uba1,E1_Ubiquitin,P0CG63,0.979664,NO,41,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-1.25,-2.582,1.332,,0.017,E,B,,-0.98,,,,PPB,-1.344,0.18783,0.00215097,0.979664 E1_Ubiquitin_R42H,E1_Ubiquitin_42,Uba1,E1_Ubiquitin,P0CG63,0.979664,NO,42,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.302,-4.151,2.849,,0.244,E,B,,-0.54,,,,PBH,-1.24667,0.18783,0.00224033,0.979664 E1_Ubiquitin_R74D,E1_Ubiquitin_74,Uba1,E1_Ubiquitin,P0CG63,0.979664,NO,74,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.302,-3.504,2.202,,0.838,T,A,,3.15,,,,HBO,-1.11333,0.18783,0.00180798,0.979664 beta-lactamase_2500_M153A,beta-lactamase_2500_153,TEM-1,beta-lactamase_2500,P62593,0.979674,NO,153,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-3.193,-2.415,-0.778,,0.14,T,A,0.55,-0.11,3.409,,77.62,PHO,-2.25767,0.361275,0.00509109,0.979674 beta-lactamase_156_L111S,beta-lactamase_156_111,TEM-1,beta-lactamase_156,P62593,0.979679,NO,111,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.76,-3.564,1.804,,0.328,T,A,0.55,0.93,2.26,,64.34,BHP,-1.884,0.111618,0.00480671,0.979679 kka2_1:1_I246L,kka2_1:1_246,Kka2,kka2_1:1,P00552,0.979685,NO,246,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-2.008,-2.197,0.189,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.520039,0.0139479,0.979685 beta-lactamase_156_V78F,beta-lactamase_156_78,TEM-1,beta-lactamase_156,P62593,0.97969,NO,78,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.459,-3.883,2.424,,,H,A,0.44,-0.47,1.132,,63.64,HHH,-1.17833,0.111618,0.00492501,0.97969 beta-lactamase_F6F,beta-lactamase_6,TEM-1,beta-lactamase,P62593,0.979693,NO,6,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.847,-1.847,,,,,,,,1.276,,67.83,BHB,-2.076,0.221079,0.00261627,0.979693 Pab1_T145C,Pab1_145,Pab1,Pab1,P04147,0.979716,NO,145,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.067,-4.454,3.387,,0.237,H,A,0.3,0.69,,,,APH,-1.135,0.175299,0.000331088,0.979716 beta-lactamase_625_F228V,beta-lactamase_625_228,TEM-1,beta-lactamase_625,P62593,0.979717,NO,228,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-2.342,-2.889,0.547,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.213352,0.0046669,0.979717 kka2_1:8_E160I,kka2_1:8_160,Kka2,kka2_1:8,P00552,0.979721,NO,160,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.683,-4.13,2.447,,0.989,G,A,1.04,2.28,2.164,,71.59,AAA,-1.36133,0.100394,0.00935762,0.979721 kka2_1:8_E160I,kka2_1:8_160,Kka2,kka2_1:8,P00552,0.979721,NO,160,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.683,-4.13,2.447,,0.989,G,A,1.04,2.28,2.164,,71.59,AAA,-1.36133,0.100394,0.00935762,0.979721 beta-lactamase_156_L38V,beta-lactamase_156_38,TEM-1,beta-lactamase_156,P62593,0.979731,NO,38,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.343,-2.209,0.866,,0.088,H,A,0.55,0.2,13.556,13.556,64.34,PHO,-1.78033,0.111618,0.00373244,0.979731 beta-lactamase_2500_D207K,beta-lactamase_2500_207,TEM-1,beta-lactamase_2500,P62593,0.979731,NO,207,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.064,-2.897,0.833,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.361275,0.00592942,0.979731 beta-lactamase_2500_M270I,beta-lactamase_2500_270,TEM-1,beta-lactamase_2500,P62593,0.979732,NO,270,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.723,,,,0.422,H,A,1.59,1.15,2.029,,64.34,PHA,-1.70933,0.361275,0.00767762,0.979732 beta-lactamase_F14V,beta-lactamase_14,TEM-1,beta-lactamase,P62593,0.979734,NO,14,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-2.736,-2.156,-0.58,,,,,,,1.537,,93.01,HHH,-2.26133,0.221079,0.00277095,0.979734 beta-lactamase_156_E210A,beta-lactamase_156_210,TEM-1,beta-lactamase_156,P62593,0.979742,NO,210,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.319,-3.162,0.843,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.111618,0.00663582,0.979742 PSD95pdz3_F325A,PSD95pdz3_325,PSD95pdz3,PSD95pdz3,P31016,0.979743,NO,325,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.524,-2.984,1.46,5.50654,,,,,12.7236,,,,OHP,-1.314,0.0758425,0.00102273,0.979743 beta-lactamase_39_D36N,beta-lactamase_39_36,TEM-1,beta-lactamase_39,P62593,0.979746,NO,36,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.732,-3.002,0.27,,0.555,H,A,0.75,1.17,13.689,13.689,77.62,AAP,-1.91167,0.0495842,0.00476483,0.979746 PSD95pdz3_A382K,PSD95pdz3_382,PSD95pdz3,PSD95pdz3,P31016,0.979746,NO,382,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.307,-3.139,1.832,5.30282,,,,,22.472,,,,PHO,-1.24167,0.0758425,0.000249256,0.979746 beta-lactamase_625_I206F,beta-lactamase_625_206,TEM-1,beta-lactamase_625,P62593,0.979756,NO,206,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-2.429,-4.165,1.736,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.213352,0.00528934,0.979756 beta-lactamase_I275M,beta-lactamase_275,TEM-1,beta-lactamase,P62593,0.979768,NO,275,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.397,-2.78,1.383,5.3999,0.015,H,A,1,-0.52,0.836,,62.59,PHH,-1.541,0.221079,0.0141984,0.979768 beta-lactamase_L199T,beta-lactamase_199,TEM-1,beta-lactamase,P62593,0.979768,NO,199,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-2.942,-2.763,-0.179,5.57712,0.832,H,A,0.82,0.42,15.302,15.302,77.62,PHH,-2.32933,0.221079,0.0048649,0.979768 beta-lactamase_S96F,beta-lactamase_96,TEM-1,beta-lactamase,P62593,0.979768,NO,96,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.27,-4.388,2.118,5.29889,0.368,,b,0.25,0.39,32.348,32.348,73.78,HPP,-2.019,0.221079,0.00551835,0.979768 beta-lactamase_T267H,beta-lactamase_267,TEM-1,beta-lactamase,P62593,0.979768,NO,267,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.308,-4.647,2.339,5.28263,0.54,,B,0.69,-0.14,0.374,,73.78,HPH,-1.9,0.221079,0.0102128,0.979768 beta-lactamase_39_S266W,beta-lactamase_39_266,TEM-1,beta-lactamase_39,P62593,0.979772,NO,266,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.0495842,0.0140785,0.979772 beta-lactamase_625_K213Q,beta-lactamase_625_213,TEM-1,beta-lactamase_625,P62593,0.979775,NO,213,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.81,-2.028,0.218,,0.67,,A,2.34,0.29,3.924,,67.83,ABH,-1.57767,0.213352,0.00610411,0.979775 beta-lactamase_2500_V157S,beta-lactamase_2500_157,TEM-1,beta-lactamase_2500,P62593,0.97978,NO,157,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.751,-2.878,1.127,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.361275,0.00506849,0.97978 beta-lactamase_39_I229S,beta-lactamase_39_229,TEM-1,beta-lactamase_39,P62593,0.97979,NO,229,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.267,-3.615,2.348,,0.083,E,B,0.48,-0.76,1.114,,50,HHH,-1.58767,0.0495842,0.00477249,0.97979 beta-lactamase_625_V157F,beta-lactamase_625_157,TEM-1,beta-lactamase_625,P62593,0.979798,NO,157,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.751,-3.968,2.217,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.213352,0.00506849,0.979798 PSD95pdz3_G356H,PSD95pdz3_356,PSD95pdz3,PSD95pdz3,P31016,0.979802,NO,356,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.008,-4.362,3.354,4.8656,,,,,11.9575,,,,BOA,-1.22933,0.0758425,0.000623061,0.979802 beta-lactamase_156_E102N,beta-lactamase_156_102,TEM-1,beta-lactamase_156,P62593,0.979808,NO,102,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.118,-3.596,1.478,,0.722,S,B,1.04,1.82,15.721,15.721,73.08,HAH,-1.581,0.111618,0.00486633,0.979808 beta-lactamase_156_P255A,beta-lactamase_156_255,TEM-1,beta-lactamase_156,P62593,0.979809,NO,255,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.111618,0.00499612,0.979809 kka2_1:8_R44F,kka2_1:8_44,Kka2,kka2_1:8,P00552,0.979809,NO,44,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.062,-4.405,2.343,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.100394,0.00745043,0.979809 kka2_1:8_R44F,kka2_1:8_44,Kka2,kka2_1:8,P00552,0.979809,NO,44,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.062,-4.405,2.343,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.100394,0.00745043,0.979809 Pab1_L190Q,Pab1_190,Pab1,Pab1,P04147,0.979819,NO,190,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.325,-3.83,2.505,,0.489,E,B,,2.59,,,,HHH,-1.31033,0.175299,0.00132347,0.979819 beta-lactamase_0_W163L,beta-lactamase_0_163,TEM-1,beta-lactamase_0,P62593,0.979821,NO,163,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-1.843,-2.838,0.995,,0.467,,B,0.47,-0.5,13.843,13.843,63.99,BHA,-1.269,0.0500837,0.00418955,0.979821 beta-lactamase_0_E87Y,beta-lactamase_0_87,TEM-1,beta-lactamase_0,P62593,0.979823,NO,87,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.421,-4.262,2.841,,0.048,,B,1.04,0.92,1.159,,64.69,PAP,-1.969,0.0500837,0.00337888,0.979823 beta-lactamase_156_A40M,beta-lactamase_156_40,TEM-1,beta-lactamase_156,P62593,0.979832,NO,40,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.402,-4.684,3.282,,0.155,S,B,0.46,0.21,1.357,,73.78,OHB,-1.40267,0.111618,0.00490026,0.979832 beta-lactamase_39_H287M,beta-lactamase_39_287,TEM-1,beta-lactamase_39,P62593,0.979833,NO,287,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,,,,,,,,,,,,,BBH,-1.111,0.0495842,,0.979833 beta-lactamase_156_W288M,beta-lactamase_156_288,TEM-1,beta-lactamase_156,P62593,0.979834,NO,288,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,,,,,,,,,,,,,BHO,,0.111618,,0.979834 beta-lactamase_2500_K53T,beta-lactamase_2500_53,TEM-1,beta-lactamase_2500,P62593,0.979839,NO,53,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-2.313,-2.702,0.389,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.361275,0.00383383,0.979839 beta-lactamase_2500_L89M,beta-lactamase_2500_89,TEM-1,beta-lactamase_2500,P62593,0.979839,NO,89,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.096,-2.928,1.832,,0.168,T,A,0.55,0.63,2.066,,64.34,PHO,-1.75767,0.361275,0.00207068,0.979839 beta-lactamase_625_A170F,beta-lactamase_625_170,TEM-1,beta-lactamase_625,P62593,0.979843,NO,170,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.237,-2.633,1.396,,0.126,,L,0.46,-0.35,3.626,,64.69,AHH,-1.63267,0.213352,0.00431903,0.979843 beta-lactamase_625_T139V,beta-lactamase_625_139,TEM-1,beta-lactamase_625,P62593,0.979851,NO,139,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.901,-3.468,1.567,,0.216,H,A,0.22,0.39,2.256,,77.62,PPH,-2.04667,0.213352,0.00441837,0.979851 beta-lactamase_39_E102T,beta-lactamase_39_102,TEM-1,beta-lactamase_39,P62593,0.979856,NO,102,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.118,-2.156,0.038,,0.722,S,B,1.04,1.82,3.87,,73.08,HAH,-1.581,0.0495842,0.00486633,0.979856 kka2_1:1_G234D,kka2_1:1_234,Kka2,kka2_1:1,P00552,0.979861,NO,234,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-2.9,-2.299,-0.601,,0.494,H,A,0.29,-0.29,1.753,,71.59,OOA,-1.86767,0.520039,0.00984449,0.979861 beta-lactamase_156_I258F,beta-lactamase_156_258,TEM-1,beta-lactamase_156,P62593,0.979867,NO,258,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.111618,0.007931,0.979867 beta-lactamase_156_Q276K,beta-lactamase_156_276,TEM-1,beta-lactamase_156,P62593,0.979873,NO,276,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.111618,0.0191712,0.979873 beta-lactamase_625_R176E,beta-lactamase_625_176,TEM-1,beta-lactamase_625,P62593,0.979877,NO,176,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-0.863,-3.215,2.352,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.213352,0.00105554,0.979877 beta-lactamase_156_D207T,beta-lactamase_156_207,TEM-1,beta-lactamase_156,P62593,0.979903,NO,207,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.064,-2.565,0.501,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.111618,0.00592942,0.979903 beta-lactamase_39_V101D,beta-lactamase_39_101,TEM-1,beta-lactamase_39,P62593,0.979922,NO,101,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.295,-2.887,1.592,,0.342,,B,0.44,0,2.96,,73.08,HHA,-1.54367,0.0495842,0.00374492,0.979922 beta-lactamase_39_D99K,beta-lactamase_39_99,TEM-1,beta-lactamase_39,P62593,0.979926,NO,99,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.191,-3.447,2.256,,0.402,G,A,0.75,0.36,0.374,,64.69,PAH,-1.794,0.0495842,0.00305446,0.979926 beta-lactamase_625_F228H,beta-lactamase_625_228,TEM-1,beta-lactamase_625,P62593,0.979927,NO,228,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-2.342,-3.331,0.989,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.213352,0.0046669,0.979927 beta-lactamase_156_E175Y,beta-lactamase_156_175,TEM-1,beta-lactamase_156,P62593,0.979949,NO,175,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.336,-4.303,1.967,,0.551,,A,1.04,1.05,2.334,,77.62,AAB,-1.31233,0.111618,0.00482205,0.979949 kka2_1:8_V46L,kka2_1:8_46,Kka2,kka2_1:8,P00552,0.979949,NO,46,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-2.62,-3.558,0.938,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.100394,0.00631301,0.979949 kka2_1:8_V46L,kka2_1:8_46,Kka2,kka2_1:8,P00552,0.979949,NO,46,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-2.62,-3.558,0.938,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.100394,0.00631301,0.979949 beta-lactamase_39_L47I,beta-lactamase_39_47,TEM-1,beta-lactamase_39,P62593,0.979951,NO,47,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.876,-2.384,0.508,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.0495842,0.00439844,0.979951 beta-lactamase_156_M127T,beta-lactamase_156_127,TEM-1,beta-lactamase_156,P62593,0.979953,NO,127,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-2.251,-2.593,0.342,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.111618,0.00437927,0.979953 beta-lactamase_625_K254T,beta-lactamase_625_254,TEM-1,beta-lactamase_625,P62593,0.979953,NO,254,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.213352,0.00369,0.979953 beta-lactamase_39_K286Q,beta-lactamase_39_286,TEM-1,beta-lactamase_39,P62593,0.979958,NO,286,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.0495842,,0.979958 beta-lactamase_39_S96C,beta-lactamase_39_96,TEM-1,beta-lactamase_39,P62593,0.979961,NO,96,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.27,-5.145,2.875,,0.368,,b,0.27,0.39,2.516,,73.78,HPP,-2.019,0.0495842,0.00551835,0.979961 beta-lactamase_2500_L55M,beta-lactamase_2500_55,TEM-1,beta-lactamase_2500,P62593,0.979963,NO,55,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.86,-4.329,2.469,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.361275,0.00403741,0.979963 beta-lactamase_625_D33T,beta-lactamase_625_33,TEM-1,beta-lactamase_625,P62593,0.979963,NO,33,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.321,-2.667,0.346,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.213352,0.00435556,0.979963 kka2_1:8_A129V,kka2_1:8_129,Kka2,kka2_1:8,P00552,0.979966,NO,129,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.656,-3.024,1.368,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.100394,0.00726862,0.979966 kka2_1:8_A129V,kka2_1:8_129,Kka2,kka2_1:8,P00552,0.979966,NO,129,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.656,-3.024,1.368,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.100394,0.00726862,0.979966 beta-lactamase_H94D,beta-lactamase_94,TEM-1,beta-lactamase,P62593,0.979973,NO,94,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-2.5,-3,0.5,6.1507,0.776,,B,0.63,1.24,1.176,,77.62,HBH,-1.872,0.221079,0.00389226,0.979973 kka2_1:2_N200E,kka2_1:2_200,Kka2,kka2_1:2,P00552,0.979974,NO,200,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-2.446,-2.236,-0.21,,0.756,T,L,0.61,-0.08,2.836,,64.39,APO,-2.08,0.295029,0.00838549,0.979974 beta-lactamase_156_D99N,beta-lactamase_156_99,TEM-1,beta-lactamase_156,P62593,0.979977,NO,99,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.191,-3.466,2.275,,0.402,G,A,0.75,0.36,3.529,,64.69,PAH,-1.794,0.111618,0.00305446,0.979977 beta-lactamase_156_Q204A,beta-lactamase_156_204,TEM-1,beta-lactamase_156,P62593,0.979977,NO,204,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-1.382,-2.589,1.207,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.111618,0.00364106,0.979977 PSD95pdz3_D357V,PSD95pdz3_357,PSD95pdz3,PSD95pdz3,P31016,0.979979,NO,357,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.264,-3.435,2.171,5.22306,,,,,10.975,,,,OAP,-1.32367,0.0758425,0.000609015,0.979979 beta-lactamase_156_R239N,beta-lactamase_156_239,TEM-1,beta-lactamase_156,P62593,0.97998,NO,239,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.111618,0.00213852,0.97998 beta-lactamase_39_D99G,beta-lactamase_39_99,TEM-1,beta-lactamase_39,P62593,0.979982,NO,99,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.191,-3.32,2.129,,0.402,G,A,0.75,0.36,0.374,,64.69,PAH,-1.794,0.0495842,0.00305446,0.979982 beta-lactamase_156_F58T,beta-lactamase_156_58,TEM-1,beta-lactamase_156,P62593,0.979988,NO,58,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-2.914,-2.91,-0.004,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.111618,0.00523369,0.979988 beta-lactamase_39_V117S,beta-lactamase_39_117,TEM-1,beta-lactamase_39,P62593,0.979995,NO,117,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.53,-3.729,2.199,,,H,A,0.44,-0.34,1.182,,65.03,PHB,-1.741,0.0495842,0.00467906,0.979995 beta-lactamase_P172R,beta-lactamase_172,TEM-1,beta-lactamase,P62593,0.980014,NO,172,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.998,-3.96,2.962,5.98941,0.639,T,b,1.1,0.24,2.087,,74.48,HOP,-2.03067,0.221079,0.00312594,0.980014 beta-lactamase_0_V29P,beta-lactamase_0_29,TEM-1,beta-lactamase_0,P62593,0.980016,NO,29,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-2.856,-3.853,0.997,,0.733,H,A,0.44,-0.78,21.916,21.916,93.01,HHB,-2.24733,0.0500837,0.00318969,0.980016 beta-lactamase_2500_Q276R,beta-lactamase_2500_276,TEM-1,beta-lactamase_2500,P62593,0.980016,NO,276,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.361275,0.0191712,0.980016 beta-lactamase_2500_V82I,beta-lactamase_2500_82,TEM-1,beta-lactamase_2500,P62593,0.98003,NO,82,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.325,-2.197,0.872,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.361275,0.00397046,0.98003 kka2_1:2_G55R,kka2_1:2_55,Kka2,kka2_1:2,P00552,0.980049,NO,55,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.625,-4.045,2.42,,0.517,S,b,0.75,1.19,15.753,15.753,63.64,POH,-2.05967,0.295029,0.00667877,0.980049 beta-lactamase_39_M115Y,beta-lactamase_39_115,TEM-1,beta-lactamase_39,P62593,0.980051,NO,115,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.389,-3.961,2.572,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.0495842,0.0034337,0.980051 beta-lactamase_39_L111A,beta-lactamase_39_111,TEM-1,beta-lactamase_39,P62593,0.980055,NO,111,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.76,-2.229,0.469,,0.328,T,A,0.55,0.93,4.334,,64.34,BHP,-1.884,0.0495842,0.00480671,0.980055 beta-lactamase_2500_P60K,beta-lactamase_2500_60,TEM-1,beta-lactamase_2500,P62593,0.980059,NO,60,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-2.469,-3.557,1.088,,0.256,T,A,0.52,-0.56,1.581,,77.62,BOA,-1.97633,0.361275,0.00521318,0.980059 beta-lactamase_39_T27M,beta-lactamase_39_27,TEM-1,beta-lactamase_39,P62593,0.980064,NO,27,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.905,-4.581,2.676,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.0495842,0.00306559,0.980064 kka2_1:4_G43F,kka2_1:4_43,Kka2,kka2_1:4,P00552,0.980064,NO,43,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.587,-4.379,2.792,,0.862,T,l,0.75,-0.67,2.247,,63.26,POB,-2.18533,0.168804,0.0071925,0.980064 beta-lactamase_R92T,beta-lactamase_92,TEM-1,beta-lactamase,P62593,0.98007,NO,92,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.718,-2.88,1.162,5.65832,0.479,E,B,0.91,1.36,3.069,,65.38,BBH,-1.50367,0.221079,0.00429626,0.98007 beta-lactamase_2500_E272I,beta-lactamase_2500_272,TEM-1,beta-lactamase_2500,P62593,0.980074,NO,272,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.361275,0.00545371,0.980074 beta-lactamase_2500_F149I,beta-lactamase_2500_149,TEM-1,beta-lactamase_2500,P62593,0.980082,NO,149,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.299,-3.576,2.277,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.361275,0.00418462,0.980082 kka2_1:1_Q61H,kka2_1:1_61,Kka2,kka2_1:1,P00552,0.980085,NO,61,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.982,-4.796,1.814,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.520039,0.00612092,0.980085 beta-lactamase_2500_A225I,beta-lactamase_2500_225,TEM-1,beta-lactamase_2500,P62593,0.98009,NO,225,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.845,-4.041,2.196,,1,T,B,0.46,-0.38,0.551,,74.48,OHO,-1.39967,0.361275,0.00465057,0.98009 beta-lactamase_39_A215R,beta-lactamase_39_215,TEM-1,beta-lactamase_39,P62593,0.980091,NO,215,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.503,-3.862,2.359,,,,a,0.46,-0.93,0.494,,74.48,HHO,-1.42633,0.0495842,0.00544007,0.980091 beta-lactamase_2500_Q276K,beta-lactamase_2500_276,TEM-1,beta-lactamase_2500,P62593,0.980094,NO,276,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.361275,0.0191712,0.980094 beta-lactamase_156_D161V,beta-lactamase_156_161,TEM-1,beta-lactamase_156,P62593,0.980097,NO,161,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.891,-3.753,2.862,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.111618,0.000897697,0.980097 beta-lactamase_39_G216H,beta-lactamase_39_216,TEM-1,beta-lactamase_39,P62593,0.980097,NO,216,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.477,-4.598,3.121,,0.437,I,A,0.29,-0.58,0.834,,74.48,HOO,-1.68067,0.0495842,0.00639568,0.980097 beta-lactamase_625_H287T,beta-lactamase_625_287,TEM-1,beta-lactamase_625,P62593,0.980106,NO,287,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,,,,,,,,,,,,,BBH,-1.111,0.213352,,0.980106 beta-lactamase_39_P255E,beta-lactamase_39_255,TEM-1,beta-lactamase_39,P62593,0.98011,NO,255,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.0495842,0.00499612,0.98011 beta-lactamase_156_G141M,beta-lactamase_156_141,TEM-1,beta-lactamase_156,P62593,0.980114,NO,141,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.828,-4.966,4.138,,0.575,T,l,0.29,-0.28,0.198,,64.69,HOO,-1.08933,0.111618,0.0012419,0.980114 beta-lactamase_39_E35K,beta-lactamase_39_35,TEM-1,beta-lactamase_39,P62593,0.980115,NO,35,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-0.869,-3.075,2.206,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.0495842,0.00174441,0.980115 beta-lactamase_2500_H24T,beta-lactamase_2500_24,TEM-1,beta-lactamase_2500,P62593,0.980116,NO,24,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-2.481,-2.645,0.164,,,,,,,0.467,,93.01,OBO,-2.0035,0.361275,0.00238894,0.980116 beta-lactamase_2500_T187N,beta-lactamase_2500_187,TEM-1,beta-lactamase_2500,P62593,0.98012,NO,187,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.401,-2.373,0.972,,0.007,H,A,0.22,-1.19,3.91,,67.48,PPH,-1.69633,0.361275,0.00491782,0.98012 beta-lactamase_39_A182C,beta-lactamase_39_182,TEM-1,beta-lactamase_39,P62593,0.980121,NO,182,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.777,-5.025,3.248,,0.136,H,A,0.46,-0.66,2.598,,93.01,OHH,-1.27367,0.0495842,0.00559099,0.980121 kka2_1:8_E149D,kka2_1:8_149,Kka2,kka2_1:8,P00552,0.980123,NO,149,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.994,-2.359,0.365,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.100394,0.00803343,0.980123 kka2_1:8_E149D,kka2_1:8_149,Kka2,kka2_1:8,P00552,0.980123,NO,149,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.994,-2.359,0.365,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.100394,0.00803343,0.980123 beta-lactamase_2500_Y262F,beta-lactamase_2500_262,TEM-1,beta-lactamase_2500,P62593,0.980126,NO,262,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.361275,0.00853516,0.980126 beta-lactamase_39_I140Y,beta-lactamase_39_140,TEM-1,beta-lactamase_39,P62593,0.980126,NO,140,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.733,-3.996,2.263,,0.128,H,A,0.48,0.41,1.16,,73.08,PHO,-1.48733,0.0495842,0.00597777,0.980126 beta-lactamase_625_E210A,beta-lactamase_625_210,TEM-1,beta-lactamase_625,P62593,0.980128,NO,210,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.319,-3.162,0.843,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.213352,0.00663582,0.980128 PSD95pdz3_P346V,PSD95pdz3_346,PSD95pdz3,PSD95pdz3,P31016,0.980143,NO,346,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.236,-3.21,1.974,5.02406,,,,,14.6629,,,,OOH,-1.18367,0.0758425,0.000758563,0.980143 kka2_1:2_L152M,kka2_1:2_152,Kka2,kka2_1:2,P00552,0.980151,NO,152,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.521,-3.313,1.792,,0.547,.,A,0.55,1.36,4.526,,63.64,OHH,-1.162,0.295029,0.00674868,0.980151 beta-lactamase_A170W,beta-lactamase_170,TEM-1,beta-lactamase,P62593,0.980156,NO,170,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.237,-5.233,3.996,5.19261,0.126,,L,2.34,-0.35,2.427,,64.69,AHH,-1.63267,0.221079,0.00431903,0.980156 beta-lactamase_A266N,beta-lactamase_266,TEM-1,beta-lactamase,P62593,0.980156,NO,266,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.369,-3.905,2.536,5.02057,0.175,S,B,0.52,0.07,1.832,,64.34,PHP,-2.08567,0.221079,0.0140785,0.980156 beta-lactamase_A84K,beta-lactamase_84,TEM-1,beta-lactamase,P62593,0.980156,NO,84,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.651,-2.484,0.833,5.28927,0.65,T,A,0.52,0.96,1.863,,68.18,AHO,-1.24267,0.221079,0.00503822,0.980156 beta-lactamase_D207V,beta-lactamase_207,TEM-1,beta-lactamase,P62593,0.980156,NO,207,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.064,-3.771,1.707,5.40404,0.409,H,A,0.23,0.12,1.975,,77.62,HAH,-1.77033,0.221079,0.00592942,0.980156 beta-lactamase_E108H,beta-lactamase_108,TEM-1,beta-lactamase,P62593,0.980156,NO,108,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.46,-4.53,3.07,5.52079,0.572,G,A,0.52,1.87,1.973,,72.73,PAB,-1.437,0.221079,0.00413372,0.980156 beta-lactamase_L120M,beta-lactamase_120,TEM-1,beta-lactamase,P62593,0.980156,NO,120,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.044,-4.046,3.002,5.11974,,H,A,1.3,-1.13,1.988,,64.69,AHO,-1.13633,0.221079,0.00143563,0.980156 beta-lactamase_L199K,beta-lactamase_199,TEM-1,beta-lactamase,P62593,0.980156,NO,199,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-2.942,-2.994,0.052,5.57712,0.832,H,A,0.82,0.42,15.302,15.302,77.62,PHH,-2.32933,0.221079,0.0048649,0.980156 beta-lactamase_M180F,beta-lactamase_180,TEM-1,beta-lactamase,P62593,0.980156,NO,180,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-2.795,-3.981,1.186,4.96809,0.242,,B,1.07,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.221079,0.00552048,0.980156 beta-lactamase_N98M,beta-lactamase_98,TEM-1,beta-lactamase,P62593,0.980156,NO,98,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-2.973,-4.74,1.767,6.59973,0.963,G,A,1.07,1.35,1.332,,77.62,PPA,-2.07867,0.221079,0.00505389,0.980156 beta-lactamase_P25V,beta-lactamase_25,TEM-1,beta-lactamase,P62593,0.980156,NO,25,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.526,-3.565,2.039,5.6134,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.221079,0.00347571,0.980156 beta-lactamase_S281M,beta-lactamase_281,TEM-1,beta-lactamase,P62593,0.980156,NO,281,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.247,-4.407,2.16,4.73591,0.128,H,A,0.25,-0.26,2.144,,77.62,HPH,-1.847,0.221079,0.0406482,0.980156 beta-lactamase_T116E,beta-lactamase_116,TEM-1,beta-lactamase,P62593,0.980156,NO,116,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.28,-3.469,2.189,4.78335,0.115,E,B,0.69,-0.12,0.343,,67.48,HPH,-1.39967,0.221079,0.00336175,0.980156 beta-lactamase_T147V,beta-lactamase_147,TEM-1,beta-lactamase,P62593,0.980156,NO,147,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.149,-3.22,2.071,5.37474,0.281,H,A,0.8,-0.68,2.838,,64.34,HPH,-1.456,0.221079,0.00226017,0.980156 beta-lactamase_V8M,beta-lactamase_8,TEM-1,beta-lactamase,P62593,0.980156,NO,8,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-2.358,-2.486,0.128,,,,,,,0.575,,77.62,BHH,-2.06267,0.221079,0.00226401,0.980156 kka2_1:8_L165S,kka2_1:8_165,Kka2,kka2_1:8,P00552,0.980158,NO,165,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-2.453,-3.581,1.128,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.100394,0.00801161,0.980158 kka2_1:8_L165S,kka2_1:8_165,Kka2,kka2_1:8,P00552,0.980158,NO,165,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-2.453,-3.581,1.128,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.100394,0.00801161,0.980158 beta-lactamase_2500_A278M,beta-lactamase_2500_278,TEM-1,beta-lactamase_2500,P62593,0.980161,NO,278,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.361275,0.0310297,0.980161 beta-lactamase_625_L197R,beta-lactamase_625_197,TEM-1,beta-lactamase_625,P62593,0.980161,NO,197,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.853,-3.93,3.077,,0.007,S,B,0.55,0.33,1.756,,60.14,HHP,-1.833,0.213352,0.00144602,0.980161 beta-lactamase_39_E62M,beta-lactamase_39_62,TEM-1,beta-lactamase_39,P62593,0.980168,NO,62,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.193,-4.77,3.577,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.0495842,0.00264802,0.980168 beta-lactamase_156_P255G,beta-lactamase_156_255,TEM-1,beta-lactamase_156,P62593,0.980172,NO,255,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.111618,0.00499612,0.980172 beta-lactamase_156_G85D,beta-lactamase_156_85,TEM-1,beta-lactamase_156,P62593,0.980174,NO,85,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.011,-2.383,1.372,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.111618,0.00252173,0.980174 beta-lactamase_39_G236C,beta-lactamase_39_236,TEM-1,beta-lactamase_39,P62593,0.980175,NO,236,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.784,-4.991,4.207,,0.241,,b,0.29,-0.59,1.883,,64.69,HOO,-1.025,0.0495842,0.00162372,0.980175 beta-lactamase_S221V,beta-lactamase_221,TEM-1,beta-lactamase,P62593,0.980179,NO,221,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.754,-3.416,1.662,5.77407,0.624,H,A,0.74,-0.2,0.383,,74.48,BPH,-1.59967,0.221079,0.0046094,0.980179 beta-lactamase_2500_T198K,beta-lactamase_2500_198,TEM-1,beta-lactamase_2500,P62593,0.980181,NO,198,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.168,-2.548,0.38,,0.489,,B,0.22,-0.13,0.37,,73.78,HPH,-1.98767,0.361275,0.004311,0.980181 beta-lactamase_156_Q203H,beta-lactamase_156_203,TEM-1,beta-lactamase_156,P62593,0.980183,NO,203,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.168,-4.663,2.495,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.111618,0.00631514,0.980183 beta-lactamase_156_G142K,beta-lactamase_156_142,TEM-1,beta-lactamase_156,P62593,0.980184,NO,142,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.707,-3.645,2.938,,0.034,,p,0.29,-0.64,0.325,,64.69,OOO,-0.834,0.111618,0.00060149,0.980184 beta-lactamase_156_T27M,beta-lactamase_156_27,TEM-1,beta-lactamase_156,P62593,0.980186,NO,27,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.905,-4.581,2.676,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.111618,0.00306559,0.980186 beta-lactamase_39_I229V,beta-lactamase_39_229,TEM-1,beta-lactamase_39,P62593,0.980189,NO,229,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.267,-1.684,0.417,,0.083,E,B,0.48,-0.76,1.114,,50,HHH,-1.58767,0.0495842,0.00477249,0.980189 beta-lactamase_625_P217F,beta-lactamase_625_217,TEM-1,beta-lactamase_625,P62593,0.9802,NO,217,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-2.062,-4.432,2.37,,0.496,I,A,0.52,-0.33,1.087,,74.48,OOH,-1.64333,0.213352,0.00463211,0.9802 beta-lactamase_39_P250F,beta-lactamase_39_250,TEM-1,beta-lactamase_39,P62593,0.980219,NO,250,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.0495842,0.00550899,0.980219 beta-lactamase_39_L192M,beta-lactamase_39_192,TEM-1,beta-lactamase_39,P62593,0.980221,NO,192,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.254,-4.084,2.83,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.0495842,0.00558728,0.980221 beta-lactamase_39_D207R,beta-lactamase_39_207,TEM-1,beta-lactamase_39,P62593,0.980227,NO,207,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.064,-2.841,0.777,,0.409,H,A,0.75,0.12,14.511,14.511,77.62,HAH,-1.77033,0.0495842,0.00592942,0.980227 beta-lactamase_I11I,beta-lactamase_11,TEM-1,beta-lactamase,P62593,0.980227,NO,11,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.745,-1.745,,,,,,,,3.135,,66.08,HHO,-1.79467,0.221079,0.00261325,0.980227 beta-lactamase_2500_S80M,beta-lactamase_2500_80,TEM-1,beta-lactamase_2500,P62593,0.980234,NO,80,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.029,-4.671,2.642,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.361275,0.00565569,0.980234 beta-lactamase_2500_N152G,beta-lactamase_2500_152,TEM-1,beta-lactamase_2500,P62593,0.980236,NO,152,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-2.757,-2.26,-0.497,,0.863,H,A,0.61,0.92,2.061,,77.62,BPH,-2.97,0.361275,0.00471429,0.980236 beta-lactamase_39_R257N,beta-lactamase_39_257,TEM-1,beta-lactamase_39,P62593,0.980237,NO,257,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.0495842,0.00756629,0.980237 beta-lactamase_39_H287L,beta-lactamase_39_287,TEM-1,beta-lactamase_39,P62593,0.980239,NO,287,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,,,,,,,,,,,,,BBH,-1.111,0.0495842,,0.980239 Pab1_N139G,Pab1_139,Pab1,Pab1,P04147,0.98025,NO,139,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-1.079,-2.725,1.646,,0.062,H,A,,-0.73,,,,APB,-1.09667,0.175299,0.000339145,0.98025 beta-lactamase_625_T126I,beta-lactamase_625_126,TEM-1,beta-lactamase_625,P62593,0.980251,NO,126,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.122,-3.78,2.658,,0.05,H,A,0.22,-0.05,0.817,,44.41,HPH,-1.60467,0.213352,0.00244552,0.980251 beta-lactamase_156_S96C,beta-lactamase_156_96,TEM-1,beta-lactamase_156,P62593,0.980256,NO,96,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.27,-5.145,2.875,,0.368,,b,0.27,0.39,2.838,,73.78,HPP,-2.019,0.111618,0.00551835,0.980256 beta-lactamase_R238S,beta-lactamase_238,TEM-1,beta-lactamase,P62593,0.980256,NO,238,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.002,-3.476,1.474,5.87663,0.564,T,L,0.45,1.09,4.195,,72.73,ABO,-1.62633,0.221079,0.00743256,0.980256 beta-lactamase_T198G,beta-lactamase_198,TEM-1,beta-lactamase,P62593,0.980257,NO,198,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.168,-3.295,1.127,4.9209,0.489,,B,0.69,-0.13,0.37,,73.78,HPH,-1.98767,0.221079,0.004311,0.980257 Pab1_L190R,Pab1_190,Pab1,Pab1,P04147,0.980262,NO,190,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.325,-3.758,2.433,,0.489,E,B,,2.59,,,,HHH,-1.31033,0.175299,0.00132347,0.980262 beta-lactamase_156_Q267V,beta-lactamase_156_267,TEM-1,beta-lactamase_156,P62593,0.980264,NO,267,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.111618,0.0102128,0.980264 beta-lactamase_2500_S201G,beta-lactamase_2500_201,TEM-1,beta-lactamase_2500,P62593,0.980276,NO,201,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.183,-2.39,1.207,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.361275,0.00198815,0.980276 beta-lactamase_39_T27E,beta-lactamase_39_27,TEM-1,beta-lactamase_39,P62593,0.98028,NO,27,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.905,-2.714,0.809,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.0495842,0.00306559,0.98028 beta-lactamase_39_R189M,beta-lactamase_39_189,TEM-1,beta-lactamase_39,P62593,0.980286,NO,189,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.844,-4.718,2.874,,0.278,H,A,1.2,1.01,12.11,12.11,72.73,HBB,-1.668,0.0495842,0.0050699,0.980286 beta-lactamase_156_P224N,beta-lactamase_156_224,TEM-1,beta-lactamase_156,P62593,0.980294,NO,224,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.893,-3.802,2.909,,0.383,,B,0.52,-0.3,0.383,,74.48,HOH,-1.26433,0.111618,0.00189564,0.980294 kka2_1:8_P179Q,kka2_1:8_179,Kka2,kka2_1:8,P00552,0.980298,NO,179,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.974,-4.023,3.049,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.100394,0.00298346,0.980298 kka2_1:8_P179Q,kka2_1:8_179,Kka2,kka2_1:8,P00552,0.980298,NO,179,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.974,-4.023,3.049,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.100394,0.00298346,0.980298 beta-lactamase_625_Q203A,beta-lactamase_625_203,TEM-1,beta-lactamase_625,P62593,0.980306,NO,203,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.168,-2.117,-0.051,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.213352,0.00631514,0.980306 beta-lactamase_E270R,beta-lactamase_270,TEM-1,beta-lactamase,P62593,0.980309,NO,270,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.723,-2.953,1.23,5.33196,0.422,H,A,0.52,1.15,1.745,,64.34,AAB,-1.70933,0.221079,0.00767762,0.980309 kka2_1:8_D227H,kka2_1:8_227,Kka2,kka2_1:8,P00552,0.980315,NO,227,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.758,-4.528,2.77,,0.128,H,A,0.75,-0.63,0.281,,56.06,BAH,-1.43067,0.100394,0.00745029,0.980315 kka2_1:8_D227H,kka2_1:8_227,Kka2,kka2_1:8,P00552,0.980315,NO,227,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.758,-4.528,2.77,,0.128,H,A,0.75,-0.63,0.281,,56.06,BAH,-1.43067,0.100394,0.00745029,0.980315 beta-lactamase_625_F228Y,beta-lactamase_625_228,TEM-1,beta-lactamase_625,P62593,0.980317,NO,228,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-2.342,-4.005,1.663,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.213352,0.0046669,0.980317 beta-lactamase_39_G249W,beta-lactamase_39_249,TEM-1,beta-lactamase_39,P62593,0.98032,NO,249,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.312,,,,0.256,S,B,0.23,0.04,30.841,30.841,72.73,HOO,-1.81367,0.0495842,0.00220169,0.98032 kka2_1:4_A176E,kka2_1:4_176,Kka2,kka2_1:4,P00552,0.980326,NO,176,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.621,-2.534,0.913,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.168804,0.0083587,0.980326 beta-lactamase_625_T187L,beta-lactamase_625_187,TEM-1,beta-lactamase_625,P62593,0.980332,NO,187,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.401,-2.278,0.877,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.213352,0.00491782,0.980332 gb1_K239M,gb1_239,gb1,gb1,P06654,0.980342,NO,239,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-3.043,-4.397,1.354,,,,,,,1.326,,45.54,HBO,-2.31467,0.177985,0.00207004,0.980342 beta-lactamase_39_D207G,beta-lactamase_39_207,TEM-1,beta-lactamase_39,P62593,0.980346,NO,207,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.064,-2.283,0.219,,0.409,H,A,0.75,0.12,14.511,14.511,77.62,HAH,-1.77033,0.0495842,0.00592942,0.980346 beta-lactamase_625_K254H,beta-lactamase_625_254,TEM-1,beta-lactamase_625,P62593,0.980346,NO,254,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.213352,0.00369,0.980346 beta-lactamase_39_P165W,beta-lactamase_39_165,TEM-1,beta-lactamase_39,P62593,0.980354,NO,165,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.373,-5.352,3.979,,0.203,T,A,0.52,-0.31,3.907,,73.78,AOA,-1.359,0.0495842,0.00549538,0.980354 beta-lactamase_625_R63H,beta-lactamase_625_63,TEM-1,beta-lactamase_625,P62593,0.98036,NO,63,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-0.943,-4.313,3.37,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.213352,0.00126938,0.98036 beta-lactamase_156_D207F,beta-lactamase_156_207,TEM-1,beta-lactamase_156,P62593,0.980363,NO,207,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.064,-4.437,2.373,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.111618,0.00592942,0.980363 beta-lactamase_39_D271A,beta-lactamase_39_271,TEM-1,beta-lactamase_39,P62593,0.980363,NO,271,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.0495842,0.00752082,0.980363 beta-lactamase_39_E108K,beta-lactamase_39_108,TEM-1,beta-lactamase_39,P62593,0.980363,NO,108,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.46,-2.182,0.722,,0.572,G,A,1.04,1.87,20.151,20.151,72.73,PAB,-1.437,0.0495842,0.00413372,0.980363 beta-lactamase_2500_A225P,beta-lactamase_2500_225,TEM-1,beta-lactamase_2500,P62593,0.980375,NO,225,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.845,-3.112,1.267,,1,T,B,0.46,-0.38,0.551,,74.48,OHO,-1.39967,0.361275,0.00465057,0.980375 beta-lactamase_625_H287W,beta-lactamase_625_287,TEM-1,beta-lactamase_625,P62593,0.980375,NO,287,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,,,,,,,,,,,,,BBH,-1.111,0.213352,,0.980375 beta-lactamase_2500_V106M,beta-lactamase_2500_106,TEM-1,beta-lactamase_2500,P62593,0.980376,NO,106,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.218,-3.026,1.808,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.361275,0.00304168,0.980376 kka2_1:1_R173L,kka2_1:1_173,Kka2,kka2_1:1,P00552,0.980379,NO,173,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.407,-2.806,0.399,,0.308,H,A,0.16,-0.13,14.756,14.756,65.53,HBH,-1.70533,0.520039,0.00784999,0.980379 beta-lactamase_625_D174N,beta-lactamase_625_174,TEM-1,beta-lactamase_625,P62593,0.980383,NO,174,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.738,-3.223,2.485,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.213352,0.00125633,0.980383 beta-lactamase_39_A182S,beta-lactamase_39_182,TEM-1,beta-lactamase_39,P62593,0.980384,NO,182,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.777,-2.825,1.048,,0.136,H,A,0.46,-0.66,2.598,,93.01,OHH,-1.27367,0.0495842,0.00559099,0.980384 kka2_1:2_K175R,kka2_1:2_175,Kka2,kka2_1:2,P00552,0.980387,NO,175,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-2.897,-2.852,-0.045,,0.579,H,A,1.3,0.51,15.629,15.629,71.59,HBH,-1.82333,0.295029,0.00693093,0.980387 beta-lactamase_39_R81H,beta-lactamase_39_81,TEM-1,beta-lactamase_39,P62593,0.980395,NO,81,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.466,-4.464,2.998,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.0495842,0.00499763,0.980395 beta-lactamase_E169V,beta-lactamase_169,TEM-1,beta-lactamase,P62593,0.980402,NO,169,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.23,-3.538,2.308,5.78896,0.337,,A,0.52,1,1.806,,73.08,PAH,-1.16533,0.221079,0.00400994,0.980402 beta-lactamase_156_D174C,beta-lactamase_156_174,TEM-1,beta-lactamase_156,P62593,0.980408,NO,174,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.738,-5.087,4.349,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.111618,0.00125633,0.980408 beta-lactamase_625_K254V,beta-lactamase_625_254,TEM-1,beta-lactamase_625,P62593,0.980414,NO,254,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.213352,0.00369,0.980414 WW_domain_Q200A,WW_domain_200,Yap65,WW_domain,P46937,0.980415,NO,200,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-1.599,-2.966,1.367,5.37476,,,,,,1.9,,70.04,HPA,-1.484,0.153962,0.00300397,0.980415 Pab1_E175Y,Pab1_175,Pab1,Pab1,P04147,0.980419,NO,175,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.055,-4.107,2.052,,,,,,,,,,AAA,-1.82667,0.175299,0.00203137,0.980419 beta-lactamase_156_I258Y,beta-lactamase_156_258,TEM-1,beta-lactamase_156,P62593,0.980422,NO,258,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.111618,0.007931,0.980422 beta-lactamase_625_L188F,beta-lactamase_625_188,TEM-1,beta-lactamase_625,P62593,0.980432,NO,188,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.166,-3.771,2.605,,,H,A,0.55,-0.3,2.982,,60.14,PHB,-1.47033,0.213352,0.00295687,0.980432 Pab1_G193C,Pab1_193,Pab1,Pab1,P04147,0.980436,NO,193,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.414,-5.033,3.619,,,,,,,,,,POP,-1.55733,0.175299,0.0014922,0.980436 beta-lactamase_156_R176G,beta-lactamase_156_176,TEM-1,beta-lactamase_156,P62593,0.980446,NO,176,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-0.863,-3.358,2.495,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.111618,0.00105554,0.980446 beta-lactamase_625_S122Q,beta-lactamase_625_122,TEM-1,beta-lactamase_625,P62593,0.980447,NO,122,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.406,-2.914,0.508,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.213352,0.00497825,0.980447 beta-lactamase_39_G142F,beta-lactamase_39_142,TEM-1,beta-lactamase_39,P62593,0.980449,NO,142,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.707,-4.29,3.583,,0.034,,p,0.29,-0.64,1.947,,64.69,OOO,-0.834,0.0495842,0.00060149,0.980449 beta-lactamase_2500_D113A,beta-lactamase_2500_113,TEM-1,beta-lactamase_2500,P62593,0.980451,NO,113,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.829,-2.412,0.583,,0.665,T,A,0.75,0.91,21.104,21.104,73.08,PAO,-1.703,0.361275,0.00474112,0.980451 beta-lactamase_156_N168C,beta-lactamase_156_168,TEM-1,beta-lactamase_156,P62593,0.980453,NO,168,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-1.029,-4.99,3.961,,0.113,G,A,0.61,-0.4,1.014,,44.41,HPA,-1.13233,0.111618,0.00288667,0.980453 beta-lactamase_2500_A268Q,beta-lactamase_2500_268,TEM-1,beta-lactamase_2500,P62593,0.980453,NO,268,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.361275,0.0102525,0.980453 beta-lactamase_39_Q37T,beta-lactamase_39_37,TEM-1,beta-lactamase_39,P62593,0.980454,NO,37,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.134,-2.508,0.374,,0.613,H,A,0.64,1.98,22.282,22.282,73.08,APH,-2.06967,0.0495842,0.00425833,0.980454 beta-lactamase_39_L120C,beta-lactamase_39_120,TEM-1,beta-lactamase_39,P62593,0.980456,NO,120,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.044,-4.81,3.766,,,H,A,0.55,-1.13,22.254,22.254,64.69,AHO,-1.13633,0.0495842,0.00143563,0.980456 beta-lactamase_2500_K53H,beta-lactamase_2500_53,TEM-1,beta-lactamase_2500,P62593,0.980458,NO,53,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-2.313,-4.67,2.357,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.361275,0.00383383,0.980458 beta-lactamase_625_R81V,beta-lactamase_625_81,TEM-1,beta-lactamase_625,P62593,0.980465,NO,81,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.466,-3.685,2.219,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.213352,0.00499763,0.980465 beta-lactamase_E102R,beta-lactamase_102,TEM-1,beta-lactamase,P62593,0.980466,NO,102,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.118,-3.801,1.683,6.36157,0.722,S,B,1.5,1.82,1.336,,73.08,HAH,-1.581,0.221079,0.00486633,0.980466 beta-lactamase_156_E56A,beta-lactamase_156_56,TEM-1,beta-lactamase_156,P62593,0.980471,NO,56,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.043,-2.078,0.035,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.111618,0.00238534,0.980471 kka2_1:4_D33C,kka2_1:4_33,Kka2,kka2_1:4,P00552,0.980471,NO,33,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.186,-5.16,2.974,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.168804,0.00633568,0.980471 beta-lactamase_G226S,beta-lactamase_226,TEM-1,beta-lactamase,P62593,0.980483,NO,226,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.461,-2.74,1.279,5.70682,0.701,T,l,0.77,-0.25,3.199,,74.48,HOH,-1.42933,0.221079,0.00665294,0.980483 beta-lactamase_156_K286Q,beta-lactamase_156_286,TEM-1,beta-lactamase_156,P62593,0.980486,NO,286,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.111618,,0.980486 beta-lactamase_2500_D252V,beta-lactamase_2500_252,TEM-1,beta-lactamase_2500,P62593,0.980491,NO,252,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.94,,,,0.766,,B,1.59,1.16,,,67.83,OAO,-2.0965,0.361275,0.00575769,0.980491 beta-lactamase_2500_A124T,beta-lactamase_2500_124,TEM-1,beta-lactamase_2500,P62593,0.980495,NO,124,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.181,-1.586,0.405,,,H,A,0.46,-0.9,0.314,,64.34,HHH,-1.152,0.361275,0.00481399,0.980495 beta-lactamase_2500_T269E,beta-lactamase_2500_269,TEM-1,beta-lactamase_2500,P62593,0.9805,NO,269,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.361275,0.00950944,0.9805 beta-lactamase_2500_E272N,beta-lactamase_2500_272,TEM-1,beta-lactamase_2500,P62593,0.980502,NO,272,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.127,-2.497,1.37,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.361275,0.00545371,0.980502 beta-lactamase_156_L188S,beta-lactamase_156_188,TEM-1,beta-lactamase_156,P62593,0.980507,NO,188,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.166,-3.587,2.421,,,H,A,0.55,-0.3,1.574,,60.14,PHB,-1.47033,0.111618,0.00295687,0.980507 beta-lactamase_625_R92A,beta-lactamase_625_92,TEM-1,beta-lactamase_625,P62593,0.980511,NO,92,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.718,-2.705,0.987,,0.479,E,B,1.2,1.36,3.069,,65.38,BBH,-1.50367,0.213352,0.00429626,0.980511 beta-lactamase_0_L28K,beta-lactamase_0_28,TEM-1,beta-lactamase_0,P62593,0.980519,NO,28,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.579,-3.608,2.029,,0.277,H,A,0.55,-0.16,9.35,9.35,93.01,PHH,-2.11333,0.0500837,0.00359321,0.980519 beta-lactamase_0_F64L,beta-lactamase_0_64,TEM-1,beta-lactamase_0,P62593,0.980521,NO,64,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-0.841,-2.908,2.067,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.0500837,0.000947691,0.980521 beta-lactamase_39_S51Q,beta-lactamase_39_51,TEM-1,beta-lactamase_39,P62593,0.980521,NO,51,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.526,-3.91,2.384,,0.496,T,A,0.27,0.26,2.964,,72.73,PPO,-1.88467,0.0495842,0.00504821,0.980521 beta-lactamase_156_V214W,beta-lactamase_156_214,TEM-1,beta-lactamase_156,P62593,0.980525,NO,214,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.299,-5.33,4.031,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.111618,0.00628442,0.980525 beta-lactamase_156_R159N,beta-lactamase_156_159,TEM-1,beta-lactamase_156,P62593,0.98053,NO,159,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-0.94,-3.445,2.505,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.111618,0.00108472,0.98053 beta-lactamase_39_S122I,beta-lactamase_39_122,TEM-1,beta-lactamase_39,P62593,0.98053,NO,122,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.406,-3.138,0.732,,0.352,H,A,0.27,-0.54,2.004,,77.62,OPH,-1.39767,0.0495842,0.00497825,0.98053 PSD95pdz3_I359V,PSD95pdz3_359,PSD95pdz3,PSD95pdz3,P31016,0.98053,NO,359,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.63,-2.085,0.455,5.35151,,,,,14.8012,,,,PHH,-1.58667,0.0758425,0.000580694,0.98053 beta-lactamase_39_L120V,beta-lactamase_39_120,TEM-1,beta-lactamase_39,P62593,0.980532,NO,120,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.044,-3.031,1.987,,,H,A,0.55,-1.13,22.254,22.254,64.69,AHO,-1.13633,0.0495842,0.00143563,0.980532 beta-lactamase_625_S80V,beta-lactamase_625_80,TEM-1,beta-lactamase_625,P62593,0.980532,NO,80,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.029,-2.695,0.666,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.213352,0.00565569,0.980532 beta-lactamase_39_Q267F,beta-lactamase_39_267,TEM-1,beta-lactamase_39,P62593,0.980541,NO,267,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.0495842,0.0102128,0.980541 kka2_1:8_P45I,kka2_1:8_45,Kka2,kka2_1:8,P00552,0.980542,NO,45,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.774,-4.097,2.323,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.100394,0.00590481,0.980542 kka2_1:8_P45I,kka2_1:8_45,Kka2,kka2_1:8,P00552,0.980542,NO,45,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.774,-4.097,2.323,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.100394,0.00590481,0.980542 beta-lactamase_39_N152C,beta-lactamase_39_152,TEM-1,beta-lactamase_39,P62593,0.980543,NO,152,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-2.757,-5.071,2.314,,0.863,H,A,0.61,0.92,4.038,,77.62,BPH,-2.97,0.0495842,0.00471429,0.980543 beta-lactamase_39_R239W,beta-lactamase_39_239,TEM-1,beta-lactamase_39,P62593,0.980548,NO,239,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.0495842,0.00213852,0.980548 beta-lactamase_625_R63S,beta-lactamase_625_63,TEM-1,beta-lactamase_625,P62593,0.980556,NO,63,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-0.943,-3.435,2.492,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.213352,0.00126938,0.980556 beta-lactamase_156_A282Q,beta-lactamase_156_282,TEM-1,beta-lactamase_156,P62593,0.980557,NO,282,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.111618,0.0449821,0.980557 beta-lactamase_39_L137H,beta-lactamase_39_137,TEM-1,beta-lactamase_39,P62593,0.980561,NO,137,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.03,-4.934,3.904,,,H,A,0.55,-0.38,0.674,,42.31,HHP,-1.58933,0.0495842,0.00278599,0.980561 beta-lactamase_0_R273A,beta-lactamase_0_273,TEM-1,beta-lactamase_0,P62593,0.980567,NO,273,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.314,-1.856,-0.458,,0.564,H,A,1.2,1.57,20.248,20.248,73.78,ABP,-1.841,0.0500837,0.0077952,0.980567 beta-lactamase_E108S,beta-lactamase_108,TEM-1,beta-lactamase,P62593,0.980573,NO,108,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.46,-2.354,0.894,5.52079,0.572,G,A,0.52,1.87,1.973,,72.73,PAB,-1.437,0.221079,0.00413372,0.980573 beta-lactamase_L191F,beta-lactamase_191,TEM-1,beta-lactamase,P62593,0.980573,NO,191,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.087,-2.754,1.667,5.72226,,H,A,1.07,0.09,1.23,,63.29,BHH,-1.445,0.221079,0.00263549,0.980573 beta-lactamase_2500_G253S,beta-lactamase_2500_253,TEM-1,beta-lactamase_2500,P62593,0.980578,NO,253,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.361275,0.00786358,0.980578 beta-lactamase_2500_S122W,beta-lactamase_2500_122,TEM-1,beta-lactamase_2500,P62593,0.980582,NO,122,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.406,-5.469,3.063,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.361275,0.00497825,0.980582 beta-lactamase_625_S221F,beta-lactamase_625_221,TEM-1,beta-lactamase_625,P62593,0.980585,NO,221,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.754,-4.221,2.467,,0.624,H,A,0.27,-0.2,1.495,,74.48,BPH,-1.59967,0.213352,0.0046094,0.980585 beta-lactamase_156_G265T,beta-lactamase_156_265,TEM-1,beta-lactamase_156,P62593,0.98059,NO,265,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.111618,0.00811926,0.98059 beta-lactamase_625_P25A,beta-lactamase_625_25,TEM-1,beta-lactamase_625,P62593,0.980598,NO,25,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.526,-2.222,0.696,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.213352,0.00347571,0.980598 beta-lactamase_39_Q37A,beta-lactamase_39_37,TEM-1,beta-lactamase_39,P62593,0.980605,NO,37,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.134,-2.542,0.408,,0.613,H,A,0.64,1.98,22.282,22.282,73.08,APH,-2.06967,0.0495842,0.00425833,0.980605 beta-lactamase_39_Y103T,beta-lactamase_39_103,TEM-1,beta-lactamase_39,P62593,0.98061,NO,103,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-1.33,-3.696,2.366,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.0495842,0.00443048,0.98061 beta-lactamase_L223M,beta-lactamase_223,TEM-1,beta-lactamase,P62593,0.980613,NO,223,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.055,-3.986,2.931,5.42318,0.27,,B,1.3,0.09,1.511,,74.48,HHO,-1.35033,0.221079,0.00372793,0.980613 beta-lactamase_156_R257I,beta-lactamase_156_257,TEM-1,beta-lactamase_156,P62593,0.980626,NO,257,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.111618,0.00756629,0.980626 Pab1_P135I,Pab1_135,Pab1,Pab1,P04147,0.980626,NO,135,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.457,-3.821,2.364,,,,,,,6.41,,81.8,BOA,-1.53367,0.175299,0.00148028,0.980626 beta-lactamase_2500_K213L,beta-lactamase_2500_213,TEM-1,beta-lactamase_2500,P62593,0.980629,NO,213,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.81,-3.558,1.748,,0.67,,A,2.34,0.29,1.668,,67.83,ABH,-1.57767,0.361275,0.00610411,0.980629 beta-lactamase_156_G90Y,beta-lactamase_156_90,TEM-1,beta-lactamase_156,P62593,0.980631,NO,90,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-2.091,-4.355,2.264,,0.598,T,A,0.29,0.32,0.319,,77.62,HOB,-1.52633,0.111618,0.00490273,0.980631 hsp90_N588Y,hsp90_588,hsp90,hsp90,P02829,0.980635,NO,588,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-3.051,-3.316,0,4.61142,0.019,H,A,0.14,0.39,,,,HPH,-3.12167,0.368192,0.000222939,0.980635 beta-lactamase_0_L188W,beta-lactamase_0_188,TEM-1,beta-lactamase_0,P62593,0.980638,NO,188,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.166,-3.108,1.942,,,H,A,0.55,-0.3,2.739,,60.14,PHB,-1.47033,0.0500837,0.00295687,0.980638 beta-lactamase_625_L111R,beta-lactamase_625_111,TEM-1,beta-lactamase_625,P62593,0.980642,NO,111,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.76,-4.077,2.317,,0.328,T,A,0.55,0.93,2.26,,64.34,BHP,-1.884,0.213352,0.00480671,0.980642 kka2_1:4_A229C,kka2_1:4_229,Kka2,kka2_1:4,P00552,0.980642,NO,229,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.739,-5.054,3.315,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.168804,0.00942138,0.980642 kka2_1:4_E231R,kka2_1:4_231,Kka2,kka2_1:4,P00552,0.980647,NO,231,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.002,-3.767,1.765,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.168804,0.00732383,0.980647 beta-lactamase_2500_E175M,beta-lactamase_2500_175,TEM-1,beta-lactamase_2500,P62593,0.98066,NO,175,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.336,-3.397,1.061,,0.551,,A,1.04,1.05,5.316,,77.62,AAB,-1.31233,0.361275,0.00482205,0.98066 beta-lactamase_T198Q,beta-lactamase_198,TEM-1,beta-lactamase,P62593,0.980661,NO,198,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.168,-2.734,0.566,4.9209,0.489,,B,0.69,-0.13,0.37,,73.78,HPH,-1.98767,0.221079,0.004311,0.980661 beta-lactamase_2500_S80K,beta-lactamase_2500_80,TEM-1,beta-lactamase_2500,P62593,0.980662,NO,80,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.029,-2.901,0.872,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.361275,0.00565569,0.980662 beta-lactamase_0_S80W,beta-lactamase_0_80,TEM-1,beta-lactamase_0,P62593,0.980665,NO,80,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.029,-5.529,3.5,,0.192,H,A,0.27,0.46,12.403,12.403,77.62,HPB,-1.44567,0.0500837,0.00565569,0.980665 kka2_1:4_D62H,kka2_1:4_62,Kka2,kka2_1:4,P00552,0.980673,NO,62,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.591,-3.352,1.761,,0.262,H,A,0.29,0.08,14.756,14.756,64.39,PAA,-1.77833,0.168804,0.00744243,0.980673 beta-lactamase_625_L47C,beta-lactamase_625_47,TEM-1,beta-lactamase_625,P62593,0.980681,NO,47,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.876,-5.002,3.126,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.213352,0.00439844,0.980681 kka2_1:8_D157V,kka2_1:8_157,Kka2,kka2_1:8,P00552,0.980682,NO,157,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.993,-3.837,2.844,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.100394,0.0042313,0.980682 kka2_1:8_D157V,kka2_1:8_157,Kka2,kka2_1:8,P00552,0.980682,NO,157,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.993,-3.837,2.844,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.100394,0.0042313,0.980682 beta-lactamase_39_R275M,beta-lactamase_39_275,TEM-1,beta-lactamase_39,P62593,0.980694,NO,275,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.0495842,0.0141984,0.980694 beta-lactamase_39_T116K,beta-lactamase_39_116,TEM-1,beta-lactamase_39,P62593,0.980699,NO,116,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.28,-3.42,2.14,,0.115,E,B,0.22,-0.12,1.133,,67.48,HPH,-1.39967,0.0495842,0.00336175,0.980699 beta-lactamase_625_H94D,beta-lactamase_625_94,TEM-1,beta-lactamase_625,P62593,0.980699,NO,94,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-2.5,-3,0.5,,0.776,,B,0.17,1.24,19.42,19.42,77.62,HBH,-1.872,0.213352,0.00389226,0.980699 beta-lactamase_E277N,beta-lactamase_277,TEM-1,beta-lactamase,P62593,0.980699,NO,277,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.869,-3.651,1.782,5.51786,0.545,H,A,0.52,-0.01,2.022,,77.62,HAH,-1.45367,0.221079,0.0169305,0.980699 beta-lactamase_2500_G90Y,beta-lactamase_2500_90,TEM-1,beta-lactamase_2500,P62593,0.980704,NO,90,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-2.091,-4.355,2.264,,0.598,T,A,0.29,0.32,1.2,,77.62,HOB,-1.52633,0.361275,0.00490273,0.980704 beta-lactamase_625_L73F,beta-lactamase_625_73,TEM-1,beta-lactamase_625,P62593,0.980708,NO,73,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.507,-2.19,0.683,,,H,A,0.55,-0.64,2.933,,67.83,HHH,-1.487,0.213352,0.00488983,0.980708 Pab1_I183R,Pab1_183,Pab1,Pab1,P04147,0.980714,NO,183,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.302,-4.028,2.726,,0.308,T,B,1,1.08,1.29,,75.56,HHA,-1.27167,0.175299,0.000574345,0.980714 beta-lactamase_G90G,beta-lactamase_90,TEM-1,beta-lactamase,P62593,0.98072,NO,90,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-2.091,-2.091,,5.51991,0.598,T,A,0.23,0.32,1.791,,77.62,HOB,-1.52633,0.221079,0.00490273,0.98072 beta-lactamase_2500_S57T,beta-lactamase_2500_57,TEM-1,beta-lactamase_2500,P62593,0.980729,NO,57,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.918,-2.297,0.379,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.361275,0.00492804,0.980729 beta-lactamase_S80A,beta-lactamase_80,TEM-1,beta-lactamase,P62593,0.980739,NO,80,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.029,-1.631,-0.398,5.23748,0.192,H,A,0.25,0.46,2.256,,77.62,HPB,-1.44567,0.221079,0.00565569,0.980739 beta-lactamase_2500_T263C,beta-lactamase_2500_263,TEM-1,beta-lactamase_2500,P62593,0.98076,NO,263,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.361275,0.0110582,0.98076 beta-lactamase_39_L188T,beta-lactamase_39_188,TEM-1,beta-lactamase_39,P62593,0.980772,NO,188,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.166,-3.522,2.356,,,H,A,0.55,-0.3,2.982,,60.14,PHB,-1.47033,0.0495842,0.00295687,0.980772 beta-lactamase_39_I206G,beta-lactamase_39_206,TEM-1,beta-lactamase_39,P62593,0.980777,NO,206,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-2.429,-2.667,0.238,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.0495842,0.00528934,0.980777 beta-lactamase_2500_L28R,beta-lactamase_2500_28,TEM-1,beta-lactamase_2500,P62593,0.980782,NO,28,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.579,-2.903,1.324,,0.277,H,A,0.55,-0.16,2.716,,93.01,PHH,-2.11333,0.361275,0.00359321,0.980782 beta-lactamase_156_L137C,beta-lactamase_156_137,TEM-1,beta-lactamase_156,P62593,0.980788,NO,137,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.03,-4.702,3.672,,,H,A,0.55,-0.38,0.674,,42.31,HHP,-1.58933,0.111618,0.00278599,0.980788 beta-lactamase_625_Q86L,beta-lactamase_625_86,TEM-1,beta-lactamase_625,P62593,0.980791,NO,86,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.4,-2.558,0.158,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.213352,0.00450027,0.980791 beta-lactamase_K252Q,beta-lactamase_252,TEM-1,beta-lactamase,P62593,0.980794,NO,252,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.94,-2.759,0.819,5.56823,0.766,,B,1.82,1.16,21.796,21.796,67.83,OBO,-2.03333,0.221079,0.00575769,0.980794 kka2_1:1_T125N,kka2_1:1_125,Kka2,kka2_1:1,P00552,0.980795,NO,125,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.622,-3.781,1.159,,0.791,T,A,0.22,0.33,1.972,,92.05,BPH,-1.56933,0.520039,0.00821755,0.980795 beta-lactamase_39_M66N,beta-lactamase_39_66,TEM-1,beta-lactamase_39,P62593,0.980808,NO,66,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.362,-4.083,2.721,,0.013,,A,0.55,-0.7,1.319,,73.08,OHH,-1.49567,0.0495842,0.00412876,0.980808 beta-lactamase_2500_A268D,beta-lactamase_2500_268,TEM-1,beta-lactamase_2500,P62593,0.980819,NO,268,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.361275,0.0102525,0.980819 beta-lactamase_625_A222I,beta-lactamase_625_222,TEM-1,beta-lactamase_625,P62593,0.980828,NO,222,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.103,-3.632,1.529,,0.233,H,A,0.46,-0.25,1.448,,77.62,PHH,-1.63733,0.213352,0.00466094,0.980828 beta-lactamase_625_R92F,beta-lactamase_625_92,TEM-1,beta-lactamase_625,P62593,0.98083,NO,92,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.718,-4.33,2.612,,0.479,E,B,1.2,1.36,3.069,,65.38,BBH,-1.50367,0.213352,0.00429626,0.98083 beta-lactamase_625_P165T,beta-lactamase_625_165,TEM-1,beta-lactamase_625,P62593,0.980834,NO,165,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.373,-1.281,-0.092,,0.203,T,A,0.52,-0.31,0.414,,73.78,AOA,-1.359,0.213352,0.00549538,0.980834 beta-lactamase_39_R81T,beta-lactamase_39_81,TEM-1,beta-lactamase_39,P62593,0.980835,NO,81,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.466,-3.547,2.081,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.0495842,0.00499763,0.980835 beta-lactamase_156_G154K,beta-lactamase_156_154,TEM-1,beta-lactamase_156,P62593,0.980836,NO,154,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.823,-3.683,2.86,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.111618,0.00180205,0.980836 beta-lactamase_156_D252Q,beta-lactamase_156_252,TEM-1,beta-lactamase_156,P62593,0.980837,NO,252,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.111618,0.00575769,0.980837 Pab1_D138N,Pab1_138,Pab1,Pab1,P04147,0.980839,NO,138,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.128,-3.144,2.016,,0.427,,B,,-0.03,,,,HAP,-1.13967,0.175299,0.000567877,0.980839 kka2_1:2_E17L,kka2_1:2_17,Kka2,kka2_1:2,P00552,0.980854,NO,17,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.154,-3.123,0.969,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.295029,0.00688738,0.980854 Pab1_E181T,Pab1_181,Pab1,Pab1,P04147,0.980859,NO,181,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.767,-3.267,1.5,,,,,,,1.395,,73.83,BAH,-1.575,0.175299,0.00107557,0.980859 beta-lactamase_2500_D252K,beta-lactamase_2500_252,TEM-1,beta-lactamase_2500,P62593,0.980861,NO,252,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.94,-3.575,1.635,,0.766,,B,1.59,1.16,,,67.83,OAO,-2.0965,0.361275,0.00575769,0.980861 beta-lactamase_39_T147Y,beta-lactamase_39_147,TEM-1,beta-lactamase_39,P62593,0.980861,NO,147,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.149,-4.243,3.094,,0.281,H,A,0.22,-0.68,13.843,13.843,64.34,HPH,-1.456,0.0495842,0.00226017,0.980861 beta-lactamase_156_R81S,beta-lactamase_156_81,TEM-1,beta-lactamase_156,P62593,0.980865,NO,81,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.466,-3.386,1.92,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.111618,0.00499763,0.980865 beta-lactamase_39_A225K,beta-lactamase_39_225,TEM-1,beta-lactamase_39,P62593,0.980869,NO,225,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.845,-2.558,0.713,,1,T,B,0.46,-0.38,9.874,9.874,74.48,OHO,-1.39967,0.0495842,0.00465057,0.980869 PSD95pdz3_F340M,PSD95pdz3_340,PSD95pdz3,PSD95pdz3,P31016,0.980883,NO,340,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.524,-3.937,2.413,5.79283,,,,,11.8045,,,,PHH,-1.55767,0.0758425,0.000836987,0.980883 beta-lactamase_156_F58H,beta-lactamase_156_58,TEM-1,beta-lactamase_156,P62593,0.980886,NO,58,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-2.914,-2.092,-0.822,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.111618,0.00523369,0.980886 gb1_A246Q,gb1_246,gb1,gb1,P06654,0.980886,NO,246,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.175,-3.635,2.46,,,,,,,,,,AHH,-1.87033,0.177985,0.00190625,0.980886 gb1_K239I,gb1_239,gb1,gb1,P06654,0.980886,NO,239,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-3.043,-3.702,0.659,,,,,,,1.326,,45.54,HBO,-2.31467,0.177985,0.00207004,0.980886 beta-lactamase_2500_E26V,beta-lactamase_2500_26,TEM-1,beta-lactamase_2500,P62593,0.980891,NO,26,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.454,-2.776,0.322,,0.54,H,A,1.04,0.98,0.49,,93.01,OAP,-1.96167,0.361275,0.00297948,0.980891 beta-lactamase_156_G76F,beta-lactamase_156_76,TEM-1,beta-lactamase_156,P62593,0.980892,NO,76,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.189,-4.264,3.075,,,H,A,0.29,-0.67,3.059,,67.83,OOH,-1.22267,0.111618,0.00476637,0.980892 beta-lactamase_625_E62D,beta-lactamase_625_62,TEM-1,beta-lactamase_625,P62593,0.980892,NO,62,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.193,-2.088,0.895,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.213352,0.00264802,0.980892 kka2_1:2_M1V,kka2_1:2_1,Kka2,kka2_1:2,P00552,0.980898,NO,1,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.787,-1.867,0.08,,,,,,,1.347,,62.12,NAHH,-1.787,0.295029,0.00251939,0.980898 beta-lactamase_39_S266K,beta-lactamase_39_266,TEM-1,beta-lactamase_39,P62593,0.980901,NO,266,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.0495842,0.0140785,0.980901 beta-lactamase_156_V101S,beta-lactamase_156_101,TEM-1,beta-lactamase_156,P62593,0.980905,NO,101,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.295,-3.65,2.355,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.111618,0.00374492,0.980905 beta-lactamase_2500_M153C,beta-lactamase_2500_153,TEM-1,beta-lactamase_2500,P62593,0.980906,NO,153,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-3.193,-4.79,1.597,,0.14,T,A,0.55,-0.11,3.409,,77.62,PHO,-2.25767,0.361275,0.00509109,0.980906 beta-lactamase_625_D99M,beta-lactamase_625_99,TEM-1,beta-lactamase_625,P62593,0.980906,NO,99,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.191,-3.198,2.007,,0.402,G,A,0.75,0.36,1.318,,64.69,PAH,-1.794,0.213352,0.00305446,0.980906 beta-lactamase_0_A132T,beta-lactamase_0_132,TEM-1,beta-lactamase_0,P62593,0.980915,NO,132,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.9,-3.22,2.32,,,H,A,0.46,-0.93,2.249,,64.69,PHH,-1.138,0.0500837,0.000962524,0.980915 beta-lactamase_156_F228Y,beta-lactamase_156_228,TEM-1,beta-lactamase_156,P62593,0.98092,NO,228,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-2.342,-4.005,1.663,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.111618,0.0046669,0.98092 beta-lactamase_2500_D207L,beta-lactamase_2500_207,TEM-1,beta-lactamase_2500,P62593,0.980923,NO,207,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.064,-3.704,1.64,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.361275,0.00592942,0.980923 beta-lactamase_39_G281L,beta-lactamase_39_281,TEM-1,beta-lactamase_39,P62593,0.980929,NO,281,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.0495842,0.0406482,0.980929 beta-lactamase_2500_G253A,beta-lactamase_2500_253,TEM-1,beta-lactamase_2500,P62593,0.980935,NO,253,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.361275,0.00786358,0.980935 beta-lactamase_39_A34C,beta-lactamase_39_34,TEM-1,beta-lactamase_39,P62593,0.980941,NO,34,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.059,-4.764,2.705,,,H,A,0.46,-0.54,13.292,13.292,73.78,AHA,-1.74967,0.0495842,0.00407913,0.980941 beta-lactamase_2500_P172Q,beta-lactamase_2500_172,TEM-1,beta-lactamase_2500,P62593,0.980946,NO,172,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.998,-3.965,2.967,,0.639,T,b,0.52,0.24,4.99,,74.48,HOP,-2.03067,0.361275,0.00312594,0.980946 beta-lactamase_39_K286F,beta-lactamase_39_286,TEM-1,beta-lactamase_39,P62593,0.980949,NO,286,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.0495842,,0.980949 beta-lactamase_2500_T193L,beta-lactamase_2500_193,TEM-1,beta-lactamase_2500,P62593,0.980951,NO,193,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.914,-1.776,-0.138,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.361275,0.00482669,0.980951 beta-lactamase_39_A40P,beta-lactamase_39_40,TEM-1,beta-lactamase_39,P62593,0.980952,NO,40,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.402,-3.856,2.454,,0.155,S,B,0.46,0.21,0.783,,73.78,OHB,-1.40267,0.0495842,0.00490026,0.980952 beta-lactamase_156_M184C,beta-lactamase_156_184,TEM-1,beta-lactamase_156,P62593,0.980956,NO,184,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.593,-4.787,3.194,,,H,A,0.55,-0.87,1.671,,62.94,HHH,-1.41,0.111618,0.00356019,0.980956 beta-lactamase_39_T198D,beta-lactamase_39_198,TEM-1,beta-lactamase_39,P62593,0.980957,NO,198,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.168,-3.544,1.376,,0.489,,B,0.22,-0.13,3.614,,73.78,HPH,-1.98767,0.0495842,0.004311,0.980957 beta-lactamase_156_P105Q,beta-lactamase_156_105,TEM-1,beta-lactamase_156,P62593,0.980962,NO,105,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.813,-3.897,3.084,,0.226,T,A,0.52,0.8,1.154,,63.29,POH,-1.01533,0.111618,0.0011981,0.980962 beta-lactamase_39_R63W,beta-lactamase_39_63,TEM-1,beta-lactamase_39,P62593,0.980985,NO,63,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-0.943,-5.32,4.377,,0.218,,B,1.2,-0.31,0.326,,44.06,ABH,-0.992333,0.0495842,0.00126938,0.980985 beta-lactamase_0_T178L,beta-lactamase_0_178,TEM-1,beta-lactamase_0,P62593,0.980986,NO,178,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-0.791,-3.133,2.342,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.0500837,0.000684366,0.980986 beta-lactamase_39_H287G,beta-lactamase_39_287,TEM-1,beta-lactamase_39,P62593,0.980987,NO,287,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,,,,,,,,,,,,,BBH,-1.111,0.0495842,,0.980987 beta-lactamase_39_W288E,beta-lactamase_39_288,TEM-1,beta-lactamase_39,P62593,0.980989,NO,288,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,,,,,,,,,,,,,BHO,,0.0495842,,0.980989 beta-lactamase_39_I45E,beta-lactamase_39_45,TEM-1,beta-lactamase_39,P62593,0.98099,NO,45,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-2.421,-3.737,1.316,,,E,B,0.48,-0.3,2.256,,77.62,HHA,-2.30267,0.0495842,0.00452842,0.98099 beta-lactamase_156_S96V,beta-lactamase_156_96,TEM-1,beta-lactamase_156,P62593,0.980993,NO,96,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.27,-3.642,1.372,,0.368,,b,0.27,0.39,2.838,,73.78,HPP,-2.019,0.111618,0.00551835,0.980993 PSD95pdz3_D357A,PSD95pdz3_357,PSD95pdz3,PSD95pdz3,P31016,0.980993,NO,357,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.264,-2.984,1.72,5.22306,,,,,10.975,,,,OAP,-1.32367,0.0758425,0.000609015,0.980993 beta-lactamase_156_P255V,beta-lactamase_156_255,TEM-1,beta-lactamase_156,P62593,0.980994,NO,255,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.111618,0.00499612,0.980994 beta-lactamase_39_S96H,beta-lactamase_39_96,TEM-1,beta-lactamase_39,P62593,0.980996,NO,96,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.27,-3.418,1.148,,0.368,,b,0.27,0.39,2.516,,73.78,HPP,-2.019,0.0495842,0.00551835,0.980996 beta-lactamase_625_R176L,beta-lactamase_625_176,TEM-1,beta-lactamase_625,P62593,0.981002,NO,176,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-0.863,-3.358,2.495,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.213352,0.00105554,0.981002 beta-lactamase_39_H24S,beta-lactamase_39_24,TEM-1,beta-lactamase_39,P62593,0.981008,NO,24,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-2.481,-1.903,-0.578,,,,,,,2.708,,93.01,OBO,-2.0035,0.0495842,0.00238894,0.981008 beta-lactamase_156_R81I,beta-lactamase_156_81,TEM-1,beta-lactamase_156,P62593,0.981014,NO,81,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.466,-4.004,2.538,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.111618,0.00499763,0.981014 beta-lactamase_39_G142A,beta-lactamase_39_142,TEM-1,beta-lactamase_39,P62593,0.981014,NO,142,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.707,-2.85,2.143,,0.034,,p,0.29,-0.64,1.947,,64.69,OOO,-0.834,0.0495842,0.00060149,0.981014 beta-lactamase_M67D,beta-lactamase_67,TEM-1,beta-lactamase,P62593,0.981014,NO,67,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-2.231,-3.779,1.548,4.9618,0.006,G,P,1.07,-0.81,1.463,,65.03,HHP,-1.502,0.221079,0.00409753,0.981014 beta-lactamase_F149M,beta-lactamase_149,TEM-1,beta-lactamase,P62593,0.981024,NO,149,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.299,-4.454,3.155,5.54789,0.195,H,A,1.1,0.11,1.863,,63.99,HHH,-1.46067,0.221079,0.00418462,0.981024 beta-lactamase_T139L,beta-lactamase_139,TEM-1,beta-lactamase,P62593,0.981024,NO,139,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.901,-3.419,1.518,5.69095,0.216,H,A,0.3,0.39,2.256,,77.62,PPH,-2.04667,0.221079,0.00441837,0.981024 beta-lactamase_156_S266H,beta-lactamase_156_266,TEM-1,beta-lactamase_156,P62593,0.981025,NO,266,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.111618,0.0140785,0.981025 beta-lactamase_2500_L73A,beta-lactamase_2500_73,TEM-1,beta-lactamase_2500,P62593,0.981025,NO,73,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.507,-2.475,0.968,,,H,A,0.55,-0.64,2.178,,67.83,HHH,-1.487,0.361275,0.00488983,0.981025 beta-lactamase_625_M115Q,beta-lactamase_625_115,TEM-1,beta-lactamase_625,P62593,0.981029,NO,115,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.389,-3.893,2.504,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.213352,0.0034337,0.981029 beta-lactamase_625_A77Q,beta-lactamase_625_77,TEM-1,beta-lactamase_625,P62593,0.981034,NO,77,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.234,-4.052,2.818,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.213352,0.00282362,0.981034 beta-lactamase_625_D252E,beta-lactamase_625_252,TEM-1,beta-lactamase_625,P62593,0.981034,NO,252,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.213352,0.00575769,0.981034 beta-lactamase_39_A34R,beta-lactamase_39_34,TEM-1,beta-lactamase_39,P62593,0.981038,NO,34,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.059,-4.061,2.002,,,H,A,0.46,-0.54,13.292,13.292,73.78,AHA,-1.74967,0.0495842,0.00407913,0.981038 beta-lactamase_156_A123C,beta-lactamase_156_123,TEM-1,beta-lactamase_156,P62593,0.981042,NO,123,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.834,-4.461,3.627,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.111618,0.0010157,0.981042 beta-lactamase_2500_L191F,beta-lactamase_2500_191,TEM-1,beta-lactamase_2500,P62593,0.981065,NO,191,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.087,-2.754,1.667,,,H,A,0.55,0.09,1.703,,63.29,BHH,-1.445,0.361275,0.00263549,0.981065 Pab1_E174I,Pab1_174,Pab1,Pab1,P04147,0.981066,NO,174,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.422,-3.959,2.537,,0.578,S,A,,0.38,,,,HAA,-1.65133,0.175299,0.00077863,0.981066 beta-lactamase_39_T179A,beta-lactamase_39_179,TEM-1,beta-lactamase_39,P62593,0.981069,NO,179,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.085,-2.334,1.249,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.0495842,0.00226045,0.981069 beta-lactamase_625_Q204T,beta-lactamase_625_204,TEM-1,beta-lactamase_625,P62593,0.981078,NO,204,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-1.382,-3.549,2.167,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.213352,0.00364106,0.981078 beta-lactamase_625_H156I,beta-lactamase_625_156,TEM-1,beta-lactamase_625,P62593,0.981088,NO,156,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-3.156,-4.08,0.924,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.213352,0.00468596,0.981088 beta-lactamase_2500_Q203M,beta-lactamase_2500_203,TEM-1,beta-lactamase_2500,P62593,0.981094,NO,203,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.168,-4.659,2.491,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.361275,0.00631514,0.981094 PSD95pdz3_L353I,PSD95pdz3_353,PSD95pdz3,PSD95pdz3,P31016,0.981096,NO,353,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.347,-2.567,1.22,5.81136,,,,,17.3525,,,,AHB,-1.50533,0.0758425,0.000664742,0.981096 beta-lactamase_625_K286M,beta-lactamase_625_286,TEM-1,beta-lactamase_625,P62593,0.981102,NO,286,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.213352,,0.981102 beta-lactamase_2500_P172M,beta-lactamase_2500_172,TEM-1,beta-lactamase_2500,P62593,0.981103,NO,172,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.998,-4.616,3.618,,0.639,T,b,0.52,0.24,4.99,,74.48,HOP,-2.03067,0.361275,0.00312594,0.981103 beta-lactamase_156_Q276I,beta-lactamase_156_276,TEM-1,beta-lactamase_156,P62593,0.981121,NO,276,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.111618,0.0191712,0.981121 beta-lactamase_0_E279L,beta-lactamase_0_279,TEM-1,beta-lactamase_0,P62593,0.981132,NO,279,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.0500837,0.0192826,0.981132 beta-lactamase_39_V117G,beta-lactamase_39_117,TEM-1,beta-lactamase_39,P62593,0.981134,NO,117,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.53,-3.828,2.298,,,H,A,0.44,-0.34,1.182,,65.03,PHB,-1.741,0.0495842,0.00467906,0.981134 beta-lactamase_2500_M153W,beta-lactamase_2500_153,TEM-1,beta-lactamase_2500,P62593,0.98114,NO,153,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-3.193,-5.376,2.183,,0.14,T,A,0.55,-0.11,3.409,,77.62,PHO,-2.25767,0.361275,0.00509109,0.98114 beta-lactamase_39_E272L,beta-lactamase_39_272,TEM-1,beta-lactamase_39,P62593,0.981143,NO,272,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.127,,,,0.081,H,A,0.43,-0.97,12.983,12.983,63.64,AAB,-1.56333,0.0495842,0.00545371,0.981143 Pab1_K164Q,Pab1_164,Pab1,Pab1,P04147,0.981148,NO,164,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-2.298,-2.487,0.189,,,,,,,,,,OBP,-1.41767,0.175299,0.00255241,0.981148 beta-lactamase_39_D207P,beta-lactamase_39_207,TEM-1,beta-lactamase_39,P62593,0.981152,NO,207,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.064,-3.955,1.891,,0.409,H,A,0.75,0.12,14.511,14.511,77.62,HAH,-1.77033,0.0495842,0.00592942,0.981152 beta-lactamase_156_D113L,beta-lactamase_156_113,TEM-1,beta-lactamase_156,P62593,0.981153,NO,113,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.829,-3.651,1.822,,0.665,T,A,0.75,0.91,2.973,,73.08,PAO,-1.703,0.111618,0.00474112,0.981153 beta-lactamase_39_R176Q,beta-lactamase_39_176,TEM-1,beta-lactamase_39,P62593,0.981161,NO,176,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-0.863,-3.449,2.586,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.0495842,0.00105554,0.981161 kka2_1:2_D101Q,kka2_1:2_101,Kka2,kka2_1:2,P00552,0.981164,NO,101,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.028,-3.859,2.831,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.295029,0.00423361,0.981164 beta-lactamase_156_A225E,beta-lactamase_156_225,TEM-1,beta-lactamase_156,P62593,0.981166,NO,225,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.845,-2.246,0.401,,1,T,B,0.46,-0.38,11.722,11.722,74.48,OHO,-1.39967,0.111618,0.00465057,0.981166 beta-lactamase_156_G253W,beta-lactamase_156_253,TEM-1,beta-lactamase_156,P62593,0.981171,NO,253,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.111618,0.00786358,0.981171 beta-lactamase_39_L120I,beta-lactamase_39_120,TEM-1,beta-lactamase_39,P62593,0.981172,NO,120,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.044,-2.541,1.497,,,H,A,0.55,-1.13,22.254,22.254,64.69,AHO,-1.13633,0.0495842,0.00143563,0.981172 beta-lactamase_39_L191I,beta-lactamase_39_191,TEM-1,beta-lactamase_39,P62593,0.981172,NO,191,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.087,-3.028,1.941,,,H,A,0.55,0.09,1.372,,63.29,BHH,-1.445,0.0495842,0.00263549,0.981172 beta-lactamase_2500_L192I,beta-lactamase_2500_192,TEM-1,beta-lactamase_2500,P62593,0.981174,NO,192,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.254,-2.519,1.265,,0.095,H,A,0.55,0.35,1.902,,60.14,HHP,-1.41833,0.361275,0.00558728,0.981174 beta-lactamase_39_D113E,beta-lactamase_39_113,TEM-1,beta-lactamase_39,P62593,0.981174,NO,113,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.829,-2.32,0.491,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.0495842,0.00474112,0.981174 beta-lactamase_156_A123V,beta-lactamase_156_123,TEM-1,beta-lactamase_156,P62593,0.981183,NO,123,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.834,-2.392,1.558,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.111618,0.0010157,0.981183 beta-lactamase_39_M180D,beta-lactamase_39_180,TEM-1,beta-lactamase_39,P62593,0.981183,NO,180,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-2.795,-3.594,0.799,,0.242,,B,0.55,-0.94,3.579,,77.62,PHO,-1.56433,0.0495842,0.00552048,0.981183 beta-lactamase_156_M153K,beta-lactamase_156_153,TEM-1,beta-lactamase_156,P62593,0.981196,NO,153,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-3.193,-3.777,0.584,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.111618,0.00509109,0.981196 beta-lactamase_2500_A282W,beta-lactamase_2500_282,TEM-1,beta-lactamase_2500,P62593,0.981198,NO,282,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.361275,0.0449821,0.981198 beta-lactamase_625_E56H,beta-lactamase_625_56,TEM-1,beta-lactamase_625,P62593,0.981198,NO,56,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.043,-4.467,2.424,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.213352,0.00238534,0.981198 beta-lactamase_2500_I54F,beta-lactamase_2500_54,TEM-1,beta-lactamase_2500,P62593,0.981199,NO,54,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-2.838,-4.242,1.404,,0.669,E,B,0.48,-0.14,3.946,,73.78,BHH,-2.337,0.361275,0.00403589,0.981199 beta-lactamase_156_G85H,beta-lactamase_156_85,TEM-1,beta-lactamase_156,P62593,0.981204,NO,85,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.011,-4.646,3.635,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.111618,0.00252173,0.981204 beta-lactamase_2500_K109I,beta-lactamase_2500_109,TEM-1,beta-lactamase_2500,P62593,0.981204,NO,109,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.734,-4.102,2.368,,0.787,G,A,2.34,2.21,0.998,,72.73,ABB,-1.63333,0.361275,0.00462493,0.981204 kka2_1:8_M1V,kka2_1:8_1,Kka2,kka2_1:8,P00552,0.981204,NO,1,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.787,-1.867,0.08,,,,,,,16.725,16.725,62.12,NAHH,-1.787,0.100394,0.00251939,0.981204 kka2_1:8_M1V,kka2_1:8_1,Kka2,kka2_1:8,P00552,0.981204,NO,1,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.787,-1.867,0.08,,,,,,,16.725,16.725,62.12,NAHH,-1.787,0.100394,0.00251939,0.981204 beta-lactamase_156_E210T,beta-lactamase_156_210,TEM-1,beta-lactamase_156,P62593,0.981208,NO,210,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.319,-2.842,0.523,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.111618,0.00663582,0.981208 beta-lactamase_2500_D271M,beta-lactamase_2500_271,TEM-1,beta-lactamase_2500,P62593,0.981219,NO,271,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.361275,0.00752082,0.981219 beta-lactamase_625_E166P,beta-lactamase_625_166,TEM-1,beta-lactamase_625,P62593,0.981224,NO,166,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.756,-3.897,2.141,,0.508,G,A,1.04,1.05,2.124,,73.08,OAH,-1.42233,0.213352,0.00512989,0.981224 beta-lactamase_39_R239C,beta-lactamase_39_239,TEM-1,beta-lactamase_39,P62593,0.981229,NO,239,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.0495842,0.00213852,0.981229 beta-lactamase_625_V42T,beta-lactamase_625_42,TEM-1,beta-lactamase_625,P62593,0.981229,NO,42,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.564,-3.48,1.916,,0.017,E,B,0.44,-0.51,2.576,,63.99,BHO,-1.042,0.213352,0.00404515,0.981229 beta-lactamase_625_R92M,beta-lactamase_625_92,TEM-1,beta-lactamase_625,P62593,0.981232,NO,92,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.718,-3.339,1.621,,0.479,E,B,1.2,1.36,3.069,,65.38,BBH,-1.50367,0.213352,0.00429626,0.981232 kka2_1:8_E63L,kka2_1:8_63,Kka2,kka2_1:8,P00552,0.981239,NO,63,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-0.762,-3.611,2.849,,0.043,H,A,1.52,-0.43,,,,AAH,-1.283,0.100394,0.00118399,0.981239 kka2_1:8_E63L,kka2_1:8_63,Kka2,kka2_1:8,P00552,0.981239,NO,63,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-0.762,-3.611,2.849,,0.043,H,A,1.52,-0.43,,,,AAH,-1.283,0.100394,0.00118399,0.981239 beta-lactamase_39_P181G,beta-lactamase_39_181,TEM-1,beta-lactamase_39,P62593,0.981241,NO,181,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.813,-3.321,2.508,,,H,A,0.52,-1.14,1.946,,61.54,HOH,-1.795,0.0495842,0.000703122,0.981241 beta-lactamase_39_R176L,beta-lactamase_39_176,TEM-1,beta-lactamase_39,P62593,0.981242,NO,176,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-0.863,-3.358,2.495,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.0495842,0.00105554,0.981242 gb1_K276L,gb1_276,gb1,gb1,P06654,0.981248,NO,276,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.456,-3.198,1.742,,,,,,,0.236,,12.72,PBP,-1.65133,0.177985,0.00620493,0.981248 beta-lactamase_A183S,beta-lactamase_183,TEM-1,beta-lactamase,P62593,0.981249,NO,183,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.231,-2.011,0.78,4.84712,0.155,H,A,0.55,-0.91,12.189,,77.62,HHH,-1.53367,0.221079,0.00296631,0.981249 beta-lactamase_2500_V157W,beta-lactamase_2500_157,TEM-1,beta-lactamase_2500,P62593,0.981252,NO,157,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.751,-5.264,3.513,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.361275,0.00506849,0.981252 beta-lactamase_625_I206H,beta-lactamase_625_206,TEM-1,beta-lactamase_625,P62593,0.981258,NO,206,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-2.429,-4.842,2.413,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.213352,0.00528934,0.981258 beta-lactamase_156_T264I,beta-lactamase_156_264,TEM-1,beta-lactamase_156,P62593,0.981259,NO,264,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.111618,0.0119399,0.981259 beta-lactamase_156_T269R,beta-lactamase_156_269,TEM-1,beta-lactamase_156,P62593,0.981276,NO,269,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.111618,0.00950944,0.981276 beta-lactamase_156_G90H,beta-lactamase_156_90,TEM-1,beta-lactamase_156,P62593,0.981286,NO,90,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-2.091,-3.353,1.262,,0.598,T,A,0.29,0.32,0.319,,77.62,HOB,-1.52633,0.111618,0.00490273,0.981286 beta-lactamase_156_L137G,beta-lactamase_156_137,TEM-1,beta-lactamase_156,P62593,0.981295,NO,137,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.03,-3.837,2.807,,,H,A,0.55,-0.38,0.674,,42.31,HHP,-1.58933,0.111618,0.00278599,0.981295 beta-lactamase_2500_T138Y,beta-lactamase_2500_138,TEM-1,beta-lactamase_2500,P62593,0.981309,NO,138,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.506,-4.429,1.923,,0.662,H,A,0.22,-0.03,30.445,30.445,73.78,HPP,-1.81233,0.361275,0.00487868,0.981309 beta-lactamase_39_P255K,beta-lactamase_39_255,TEM-1,beta-lactamase_39,P62593,0.981309,NO,255,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.0495842,0.00499612,0.981309 beta-lactamase_0_P250V,beta-lactamase_0_250,TEM-1,beta-lactamase_0,P62593,0.981313,NO,250,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.0500837,0.00550899,0.981313 beta-lactamase_156_G216W,beta-lactamase_156_216,TEM-1,beta-lactamase_156,P62593,0.981315,NO,216,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.477,-5.45,3.973,,0.437,I,A,0.29,-0.58,12.464,12.464,74.48,HOO,-1.68067,0.111618,0.00639568,0.981315 beta-lactamase_39_Y95I,beta-lactamase_39_95,TEM-1,beta-lactamase_39,P62593,0.981316,NO,95,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-1.715,-1.963,0.248,,0.122,,b,0.21,-0.37,2.341,,77.62,BHP,-2.16167,0.0495842,0.00479449,0.981316 beta-lactamase_156_L100Y,beta-lactamase_156_100,TEM-1,beta-lactamase_156,P62593,0.981321,NO,100,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.218,-2.879,1.661,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.111618,0.00413885,0.981321 beta-lactamase_39_Y262F,beta-lactamase_39_262,TEM-1,beta-lactamase_39,P62593,0.981322,NO,262,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.0495842,0.00853516,0.981322 beta-lactamase_625_K254R,beta-lactamase_625_254,TEM-1,beta-lactamase_625,P62593,0.981325,NO,254,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.213352,0.00369,0.981325 beta-lactamase_F13V,beta-lactamase_13,TEM-1,beta-lactamase,P62593,0.981325,NO,13,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-2.394,-3.037,0.643,,,,,,,4.079,,77.62,OHH,-2.382,0.221079,0.0029078,0.981325 beta-lactamase_0_Y103M,beta-lactamase_0_103,TEM-1,beta-lactamase_0,P62593,0.981328,NO,103,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-1.33,-4.627,3.297,,0.613,S,l,0.21,1.21,1.646,,63.29,AHP,-1.48767,0.0500837,0.00443048,0.981328 beta-lactamase_156_L188V,beta-lactamase_156_188,TEM-1,beta-lactamase_156,P62593,0.981332,NO,188,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.166,-3.017,1.851,,,H,A,0.55,-0.3,1.574,,60.14,PHB,-1.47033,0.111618,0.00295687,0.981332 beta-lactamase_0_P25L,beta-lactamase_0_25,TEM-1,beta-lactamase_0,P62593,0.981336,NO,25,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.526,-3.586,2.06,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.0500837,0.00347571,0.981336 Pab1_E176N,Pab1_176,Pab1,Pab1,P04147,0.981338,NO,176,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.003,-3.516,1.513,,,,,,,,,,AAO,-2.09933,0.175299,0.00264426,0.981338 beta-lactamase_625_L38C,beta-lactamase_625_38,TEM-1,beta-lactamase_625,P62593,0.981345,NO,38,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.343,-4.841,3.498,,0.088,H,A,0.55,0.2,1.986,,64.34,PHO,-1.78033,0.213352,0.00373244,0.981345 beta-lactamase_39_H94F,beta-lactamase_39_94,TEM-1,beta-lactamase_39,P62593,0.981353,NO,94,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-2.5,-4.323,1.823,,0.776,,B,0.17,1.24,11.583,11.583,77.62,HBH,-1.872,0.0495842,0.00389226,0.981353 beta-lactamase_S57T,beta-lactamase_57,TEM-1,beta-lactamase,P62593,0.981354,NO,57,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.918,-2.297,0.379,5.64201,0.352,E,B,0.25,-0.18,1.971,,72.73,APH,-2.29167,0.221079,0.00492804,0.981354 Pab1_G163Q,Pab1_163,Pab1,Pab1,P04147,0.981373,NO,163,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.809,-3.941,3.132,,0.356,B,g,,0.55,,,,POB,-1.80667,0.175299,0.00030953,0.981373 beta-lactamase_156_P143E,beta-lactamase_156_143,TEM-1,beta-lactamase_156,P62593,0.981377,NO,143,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.967,-3.58,2.613,,0.075,H,A,0.52,-0.37,0.479,,66.78,OOB,-1.354,0.111618,0.00114551,0.981377 beta-lactamase_625_Y103A,beta-lactamase_625_103,TEM-1,beta-lactamase_625,P62593,0.981382,NO,103,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-1.33,-3.426,2.096,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.213352,0.00443048,0.981382 beta-lactamase_39_T179S,beta-lactamase_39_179,TEM-1,beta-lactamase_39,P62593,0.981383,NO,179,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.085,-2.228,1.143,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.0495842,0.00226045,0.981383 beta-lactamase_39_S57I,beta-lactamase_39_57,TEM-1,beta-lactamase_39,P62593,0.981385,NO,57,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.918,-3.825,1.907,,0.352,E,B,0.27,-0.18,2.3,,72.73,APH,-2.29167,0.0495842,0.00492804,0.981385 beta-lactamase_39_G39S,beta-lactamase_39_39,TEM-1,beta-lactamase_39,P62593,0.981387,NO,39,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.864,-2.342,0.478,,0.701,T,L,0.29,0.47,1.454,,77.62,HOH,-1.53633,0.0495842,0.00487611,0.981387 beta-lactamase_2500_E102K,beta-lactamase_2500_102,TEM-1,beta-lactamase_2500,P62593,0.981392,NO,102,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.118,-2.64,0.522,,0.722,S,B,1.04,1.82,1.336,,73.08,HAH,-1.581,0.361275,0.00486633,0.981392 beta-lactamase_156_Q203W,beta-lactamase_156_203,TEM-1,beta-lactamase_156,P62593,0.9814,NO,203,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.168,-5.466,3.298,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.111618,0.00631514,0.9814 beta-lactamase_2500_A170G,beta-lactamase_2500_170,TEM-1,beta-lactamase_2500,P62593,0.981408,NO,170,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.237,-1.884,0.647,,0.126,,L,0.46,-0.35,2.427,,64.69,AHH,-1.63267,0.361275,0.00431903,0.981408 beta-lactamase_625_G85T,beta-lactamase_625_85,TEM-1,beta-lactamase_625,P62593,0.981413,NO,85,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.011,-3.637,2.626,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.213352,0.00252173,0.981413 beta-lactamase_156_G90L,beta-lactamase_156_90,TEM-1,beta-lactamase_156,P62593,0.981416,NO,90,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-2.091,-3.689,1.598,,0.598,T,A,0.29,0.32,0.319,,77.62,HOB,-1.52633,0.111618,0.00490273,0.981416 beta-lactamase_S57Y,beta-lactamase_57,TEM-1,beta-lactamase,P62593,0.981429,NO,57,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.918,-4.294,2.376,5.64201,0.352,E,B,0.25,-0.18,1.971,,72.73,APH,-2.29167,0.221079,0.00492804,0.981429 gb1_A246C,gb1_246,gb1,gb1,P06654,0.981429,NO,246,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.175,-4.148,2.973,,,,,,,,,,AHH,-1.87033,0.177985,0.00190625,0.981429 E1_Ubiquitin_L73Y,E1_Ubiquitin_73,Uba1,E1_Ubiquitin,P0CG63,0.981432,NO,73,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.039,-3.755,2.716,,0.518,,B,1.3,1,,,,BHB,-1.175,0.18783,0.00111236,0.981432 E1_Ubiquitin_Q40V,E1_Ubiquitin_40,Uba1,E1_Ubiquitin,P0CG63,0.981432,NO,40,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-1.48,-3.482,2.002,,0.387,G,A,,0.03,,,,OPP,-1.365,0.18783,0.0037961,0.981432 E1_Ubiquitin_R42L,E1_Ubiquitin_42,Uba1,E1_Ubiquitin,P0CG63,0.981432,NO,42,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.302,-3.229,1.927,,0.244,E,B,,-0.54,,,,PBH,-1.24667,0.18783,0.00224033,0.981432 E1_Ubiquitin_R42T,E1_Ubiquitin_42,Uba1,E1_Ubiquitin,P0CG63,0.981432,NO,42,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.302,-3.292,1.99,,0.244,E,B,,-0.54,,,,PBH,-1.24667,0.18783,0.00224033,0.981432 beta-lactamase_39_G39R,beta-lactamase_39_39,TEM-1,beta-lactamase_39,P62593,0.981433,NO,39,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.864,-3.077,1.213,,0.701,T,L,0.29,0.47,1.454,,77.62,HOH,-1.53633,0.0495842,0.00487611,0.981433 beta-lactamase_39_S283E,beta-lactamase_39_283,TEM-1,beta-lactamase_39,P62593,0.981439,NO,283,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.0495842,0.0429138,0.981439 beta-lactamase_625_A133T,beta-lactamase_625_133,TEM-1,beta-lactamase_625,P62593,0.981443,NO,133,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.186,-2.382,1.196,,,H,A,0.46,-0.86,0.373,,67.83,HHP,-0.988333,0.213352,0.00468022,0.981443 beta-lactamase_2500_M67T,beta-lactamase_2500_67,TEM-1,beta-lactamase_2500,P62593,0.981446,NO,67,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-2.231,-3.488,1.257,,0.006,G,P,0.55,-0.81,2.653,,65.03,HHP,-1.502,0.361275,0.00409753,0.981446 beta-lactamase_156_N98E,beta-lactamase_156_98,TEM-1,beta-lactamase_156,P62593,0.98145,NO,98,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-2.973,-2.445,-0.528,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.111618,0.00505389,0.98145 beta-lactamase_156_L199T,beta-lactamase_156_199,TEM-1,beta-lactamase_156,P62593,0.981451,NO,199,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-2.942,-2.763,-0.179,,0.832,H,A,0.55,0.42,1.552,,77.62,PHH,-2.32933,0.111618,0.0048649,0.981451 kka2_1:2_D23F,kka2_1:2_23,Kka2,kka2_1:2,P00552,0.981455,NO,23,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.459,-4.448,1.989,,0.695,E,B,0.75,-0.65,18.207,18.207,65.53,HAH,-1.94033,0.295029,0.007195,0.981455 beta-lactamase_39_T139Y,beta-lactamase_39_139,TEM-1,beta-lactamase_39,P62593,0.981457,NO,139,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.901,-4.252,2.351,,0.216,H,A,0.22,0.39,0.421,,77.62,PPH,-2.04667,0.0495842,0.00441837,0.981457 beta-lactamase_625_D161V,beta-lactamase_625_161,TEM-1,beta-lactamase_625,P62593,0.981464,NO,161,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.891,-3.753,2.862,,0.341,,A,0.75,-0.52,4.655,,61.19,HAB,-0.961333,0.213352,0.000897697,0.981464 Pab1_E174Y,Pab1_174,Pab1,Pab1,P04147,0.981464,NO,174,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.422,-4.145,2.723,,0.578,S,A,,0.38,,,,HAA,-1.65133,0.175299,0.00077863,0.981464 kka2_1:4_K175Q,kka2_1:4_175,Kka2,kka2_1:4,P00552,0.98147,NO,175,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-2.897,-2.736,-0.161,,0.579,H,A,1.3,0.51,15.629,15.629,71.59,HBH,-1.82333,0.168804,0.00693093,0.98147 beta-lactamase_625_M153H,beta-lactamase_625_153,TEM-1,beta-lactamase_625,P62593,0.981475,NO,153,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-3.193,-4.946,1.753,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.213352,0.00509109,0.981475 beta-lactamase_39_T147K,beta-lactamase_39_147,TEM-1,beta-lactamase_39,P62593,0.981486,NO,147,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.149,-3.536,2.387,,0.281,H,A,0.22,-0.68,13.843,13.843,64.34,HPH,-1.456,0.0495842,0.00226017,0.981486 beta-lactamase_39_T198Q,beta-lactamase_39_198,TEM-1,beta-lactamase_39,P62593,0.981486,NO,198,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.168,-2.734,0.566,,0.489,,B,0.22,-0.13,3.614,,73.78,HPH,-1.98767,0.0495842,0.004311,0.981486 beta-lactamase_2500_I206L,beta-lactamase_2500_206,TEM-1,beta-lactamase_2500,P62593,0.981508,NO,206,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-2.429,-2.261,-0.168,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.361275,0.00528934,0.981508 beta-lactamase_156_V101I,beta-lactamase_156_101,TEM-1,beta-lactamase_156,P62593,0.981509,NO,101,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.295,-2.207,0.912,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.111618,0.00374492,0.981509 beta-lactamase_A280C,beta-lactamase_280,TEM-1,beta-lactamase,P62593,0.981513,NO,280,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.708,-4.987,3.279,4.74932,0.379,H,A,0.52,-0.72,1.785,,68.18,OHP,-1.66433,0.221079,0.0530888,0.981513 beta-lactamase_D207N,beta-lactamase_207,TEM-1,beta-lactamase,P62593,0.981513,NO,207,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.064,-2.966,0.902,5.40404,0.409,H,A,0.23,0.12,1.975,,77.62,HAH,-1.77033,0.221079,0.00592942,0.981513 beta-lactamase_E102E,beta-lactamase_102,TEM-1,beta-lactamase,P62593,0.981513,NO,102,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.118,-2.118,,6.36157,0.722,S,B,1.5,1.82,1.336,,73.08,HAH,-1.581,0.221079,0.00486633,0.981513 beta-lactamase_E237H,beta-lactamase_237,TEM-1,beta-lactamase,P62593,0.981513,NO,237,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.058,-3.354,1.296,5.42877,0.583,S,B,1.62,1.2,2.144,,77.62,OAB,-1.61467,0.221079,0.0048626,0.981513 beta-lactamase_F14M,beta-lactamase_14,TEM-1,beta-lactamase,P62593,0.981513,NO,14,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-2.736,-4.1,1.364,,,,,,,1.537,,93.01,HHH,-2.26133,0.221079,0.00277095,0.981513 beta-lactamase_H110F,beta-lactamase_110,TEM-1,beta-lactamase,P62593,0.981513,NO,110,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-1.706,-4.019,2.313,5.52635,0.341,G,a,0.35,1.08,31.31,31.31,64.69,BBH,-1.73333,0.221079,0.00441499,0.981513 beta-lactamase_H156L,beta-lactamase_156,TEM-1,beta-lactamase,P62593,0.981513,NO,156,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-3.156,-3.026,-0.13,6.00284,0.753,S,A,0.72,-0.6,6.456,6.456,77.62,ABH,-1.932,0.221079,0.00468596,0.981513 beta-lactamase_H156S,beta-lactamase_156,TEM-1,beta-lactamase,P62593,0.981513,NO,156,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-3.156,-2.584,-0.572,6.00284,0.753,S,A,0.72,-0.6,6.456,6.456,77.62,ABH,-1.932,0.221079,0.00468596,0.981513 beta-lactamase_L10I,beta-lactamase_10,TEM-1,beta-lactamase,P62593,0.981513,NO,10,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.623,-2.055,0.432,,,,,,,2.467,,65.38,HHH,-1.83833,0.221079,0.00296968,0.981513 beta-lactamase_N152N,beta-lactamase_152,TEM-1,beta-lactamase,P62593,0.981513,NO,152,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-2.757,-2.757,,5.98571,0.863,H,A,0.09,0.92,2.061,,77.62,BPH,-2.97,0.221079,0.00471429,0.981513 beta-lactamase_Q86M,beta-lactamase_86,TEM-1,beta-lactamase,P62593,0.981513,NO,86,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.4,-3.46,1.06,5.39897,0.696,S,A,0.12,2.38,2.105,,77.62,OPA,-1.61067,0.221079,0.00450027,0.981513 beta-lactamase_S2F,beta-lactamase_2,TEM-1,beta-lactamase,P62593,0.981513,NO,2,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.942,-3.858,1.916,,,,,,,2.36,,65.38,HPH,-2.02767,0.221079,0.00227352,0.981513 beta-lactamase_T138I,beta-lactamase_138,TEM-1,beta-lactamase,P62593,0.981513,NO,138,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.506,-4.099,1.593,5.52585,0.662,H,A,0.3,-0.03,30.445,30.445,73.78,HPP,-1.81233,0.221079,0.00487868,0.981513 beta-lactamase_X287N,beta-lactamase_287,TEM-1,beta-lactamase,P62593,0.981513,NO,287,X,N,XN,Stop,Polar,5.71,5.47157,-0.238425,,132.5,132,0,141.9,114.1,-27.8,,,,,,,,,,,,,HXO,-1.111,0.221079,,0.981513 beta-lactamase_156_R81W,beta-lactamase_156_81,TEM-1,beta-lactamase_156,P62593,0.981516,NO,81,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.466,-5.415,3.949,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.111618,0.00499763,0.981516 kka2_1:2_A64R,kka2_1:2_64,Kka2,kka2_1:2,P00552,0.981516,NO,64,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.496,-4.086,2.59,,0.039,H,A,0.46,-0.57,14.509,14.509,56.06,AHH,-1.334,0.295029,0.00705578,0.981516 Pab1_N192I,Pab1_192,Pab1,Pab1,P04147,0.98152,NO,192,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-1.079,-3.827,2.748,,0.619,T,l,,2.28,,,,HPO,-1.231,0.175299,0.000273498,0.98152 beta-lactamase_39_S128G,beta-lactamase_39_128,TEM-1,beta-lactamase_39,P62593,0.981527,NO,128,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-0.84,-2.908,2.068,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.0495842,0.00071483,0.981527 beta-lactamase_625_V78M,beta-lactamase_625_78,TEM-1,beta-lactamase_625,P62593,0.98153,NO,78,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.459,-2.823,1.364,,,H,A,0.44,-0.47,2.045,,63.64,HHH,-1.17833,0.213352,0.00492501,0.98153 beta-lactamase_156_E56I,beta-lactamase_156_56,TEM-1,beta-lactamase_156,P62593,0.981541,NO,56,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.043,-3.825,1.782,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.111618,0.00238534,0.981541 Pab1_G188S,Pab1_188,Pab1,Pab1,P04147,0.981545,NO,188,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.809,-2.978,2.169,,0.379,E,g,,2.18,,,,POH,-1.14633,0.175299,0.000280911,0.981545 beta-lactamase_625_V214T,beta-lactamase_625_214,TEM-1,beta-lactamase_625,P62593,0.981548,NO,214,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.299,-1.73,0.431,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.213352,0.00628442,0.981548 beta-lactamase_2500_E102M,beta-lactamase_2500_102,TEM-1,beta-lactamase_2500,P62593,0.981551,NO,102,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.118,-4.799,2.681,,0.722,S,B,1.04,1.82,1.336,,73.08,HAH,-1.581,0.361275,0.00486633,0.981551 beta-lactamase_2500_A225V,beta-lactamase_2500_225,TEM-1,beta-lactamase_2500,P62593,0.981568,NO,225,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.845,-3.655,1.81,,1,T,B,0.46,-0.38,0.551,,74.48,OHO,-1.39967,0.361275,0.00465057,0.981568 beta-lactamase_2500_Q203K,beta-lactamase_2500_203,TEM-1,beta-lactamase_2500,P62593,0.981573,NO,203,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.168,-2.642,0.474,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.361275,0.00631514,0.981573 beta-lactamase_2500_H94E,beta-lactamase_2500_94,TEM-1,beta-lactamase_2500,P62593,0.981579,NO,94,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-2.5,-2.415,-0.085,,0.776,,B,0.17,1.24,1.176,,77.62,HBH,-1.872,0.361275,0.00389226,0.981579 beta-lactamase_39_I125H,beta-lactamase_39_125,TEM-1,beta-lactamase_39,P62593,0.981579,NO,125,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.441,-4.965,3.524,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.0495842,0.00383964,0.981579 beta-lactamase_625_D252Y,beta-lactamase_625_252,TEM-1,beta-lactamase_625,P62593,0.981579,NO,252,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.213352,0.00575769,0.981579 beta-lactamase_P12L,beta-lactamase_12,TEM-1,beta-lactamase,P62593,0.98158,NO,12,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-2.016,-2.278,0.262,,,,,,,2.88,,72.73,HOH,-2.05167,0.221079,0.00241653,0.98158 hsp90_F583W,hsp90_583,hsp90,hsp90,P02829,0.981582,NO,583,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-3.22,-4.251,0,5.28185,1.112,S,l,1.1,0.87,,,,PHO,-3.003,0.368192,0.000222939,0.981582 beta-lactamase_39_L218N,beta-lactamase_39_218,TEM-1,beta-lactamase_39,P62593,0.981589,NO,218,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.391,-3.851,2.46,,,I,b,0.55,-0.53,2.038,,74.48,OHH,-1.58867,0.0495842,0.00618274,0.981589 beta-lactamase_625_T187D,beta-lactamase_625_187,TEM-1,beta-lactamase_625,P62593,0.981589,NO,187,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.401,-2.769,1.368,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.213352,0.00491782,0.981589 beta-lactamase_156_H94I,beta-lactamase_156_94,TEM-1,beta-lactamase_156,P62593,0.98159,NO,94,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-2.5,-2.913,0.413,,0.776,,B,0.17,1.24,11.583,11.583,77.62,HBH,-1.872,0.111618,0.00389226,0.98159 beta-lactamase_156_P255W,beta-lactamase_156_255,TEM-1,beta-lactamase_156,P62593,0.981592,NO,255,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.111618,0.00499612,0.981592 beta-lactamase_E277A,beta-lactamase_277,TEM-1,beta-lactamase,P62593,0.981594,NO,277,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.869,-2.319,0.45,5.51786,0.545,H,A,0.52,-0.01,2.022,,77.62,HAH,-1.45367,0.221079,0.0169305,0.981594 beta-lactamase_625_E169I,beta-lactamase_625_169,TEM-1,beta-lactamase_625,P62593,0.981602,NO,169,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.23,-3.986,2.756,,0.337,,A,1.04,1,1.806,,73.08,PAH,-1.16533,0.213352,0.00400994,0.981602 beta-lactamase_625_H287K,beta-lactamase_625_287,TEM-1,beta-lactamase_625,P62593,0.981608,NO,287,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,,,,,,,,,,,,,BBH,-1.111,0.213352,,0.981608 beta-lactamase_39_Y103G,beta-lactamase_39_103,TEM-1,beta-lactamase_39,P62593,0.981617,NO,103,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-1.33,-3.527,2.197,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.0495842,0.00443048,0.981617 beta-lactamase_2500_R275N,beta-lactamase_2500_275,TEM-1,beta-lactamase_2500,P62593,0.981618,NO,275,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.361275,0.0141984,0.981618 kka2_1:8_L53C,kka2_1:8_53,Kka2,kka2_1:8,P00552,0.981621,NO,53,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-2.681,-5.19,2.509,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.100394,0.00671168,0.981621 kka2_1:8_L53C,kka2_1:8_53,Kka2,kka2_1:8,P00552,0.981621,NO,53,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-2.681,-5.19,2.509,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.100394,0.00671168,0.981621 beta-lactamase_156_M115N,beta-lactamase_156_115,TEM-1,beta-lactamase_156,P62593,0.981626,NO,115,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.389,-4.013,2.624,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.111618,0.0034337,0.981626 beta-lactamase_156_Q97Y,beta-lactamase_156_97,TEM-1,beta-lactamase_156,P62593,0.981636,NO,97,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.072,-4.35,2.278,,0.823,G,A,0.64,2.42,4.457,,77.62,PPP,-2.43833,0.111618,0.0045116,0.981636 beta-lactamase_156_G142H,beta-lactamase_156_142,TEM-1,beta-lactamase_156,P62593,0.981639,NO,142,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.707,-4.678,3.971,,0.034,,p,0.29,-0.64,0.325,,64.69,OOO,-0.834,0.111618,0.00060149,0.981639 beta-lactamase_156_H151T,beta-lactamase_156_151,TEM-1,beta-lactamase_156,P62593,0.98164,NO,151,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-2.96,-3.492,0.532,,0.594,H,A,0.17,0.1,1.401,,77.62,HBP,-2.34767,0.111618,0.00216946,0.98164 PSD95pdz3_E331Y,PSD95pdz3_331,PSD95pdz3,PSD95pdz3,P31016,0.981643,NO,331,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.404,-3.844,2.44,5.86289,,,,,51.8889,,,,OAA,-1.22533,0.0758425,0.000950134,0.981643 PSD95pdz3_G383Y,PSD95pdz3_383,PSD95pdz3,PSD95pdz3,P31016,0.981652,NO,383,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.008,-4.069,3.061,5.17213,,,,,20.5325,,,,HOP,-1.338,0.0758425,0.000233044,0.981652 beta-lactamase_H24Q,beta-lactamase_24,TEM-1,beta-lactamase,P62593,0.981653,NO,24,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-2.481,-2.604,0.123,5.82767,,,,,,2.708,,93.01,HBO,-1.85167,0.221079,0.00238894,0.981653 beta-lactamase_2500_N98G,beta-lactamase_2500_98,TEM-1,beta-lactamase_2500,P62593,0.981656,NO,98,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-2.973,-3.401,0.428,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.361275,0.00505389,0.981656 beta-lactamase_39_C75N,beta-lactamase_39_75,TEM-1,beta-lactamase_39,P62593,0.981656,NO,75,C,N,CN,Special,Polar,5.07,5.47157,0.401575,139,121,132,11,108.5,114.1,5.6,-1.245,-3.973,2.728,,,H,A,0.46,-0.87,2.369,,50,HOO,-1.24333,0.0495842,0.0034616,0.981656 PSD95pdz3_Q391V,PSD95pdz3_391,PSD95pdz3,PSD95pdz3,P31016,0.981656,NO,391,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-1.699,-3.21,1.511,5.50275,,,,,12.6589,,,,HPH,-1.481,0.0758425,0.000990786,0.981656 beta-lactamase_2500_E279D,beta-lactamase_2500_279,TEM-1,beta-lactamase_2500,P62593,0.981663,NO,279,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.361275,0.0192826,0.981663 beta-lactamase_156_V214H,beta-lactamase_156_214,TEM-1,beta-lactamase_156,P62593,0.981673,NO,214,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.299,-4.922,3.623,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.111618,0.00628442,0.981673 beta-lactamase_39_A34M,beta-lactamase_39_34,TEM-1,beta-lactamase_39,P62593,0.981683,NO,34,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.059,-4.351,2.292,,,H,A,0.46,-0.54,13.292,13.292,73.78,AHA,-1.74967,0.0495842,0.00407913,0.981683 beta-lactamase_625_D271Y,beta-lactamase_625_271,TEM-1,beta-lactamase_625,P62593,0.981684,NO,271,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.213352,0.00752082,0.981684 beta-lactamase_S96H,beta-lactamase_96,TEM-1,beta-lactamase,P62593,0.981685,NO,96,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.27,-3.418,1.148,5.29889,0.368,,b,0.25,0.39,32.348,32.348,73.78,HPP,-2.019,0.221079,0.00551835,0.981685 beta-lactamase_625_G85Y,beta-lactamase_625_85,TEM-1,beta-lactamase_625,P62593,0.981688,NO,85,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.011,-4.409,3.398,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.213352,0.00252173,0.981688 beta-lactamase_39_H287W,beta-lactamase_39_287,TEM-1,beta-lactamase_39,P62593,0.981694,NO,287,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,,,,,,,,,,,,,BBH,-1.111,0.0495842,,0.981694 kka2_1:4_I221V,kka2_1:4_221,Kka2,kka2_1:4,P00552,0.981706,NO,221,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.739,-2.261,0.522,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.168804,0.00945908,0.981706 beta-lactamase_S254R,beta-lactamase_254,TEM-1,beta-lactamase,P62593,0.981707,NO,254,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.126,-3.89,1.764,5.49575,0.312,,a,0.25,-0.48,24.91,24.91,69.58,OPB,-2.215,0.221079,0.00369,0.981707 beta-lactamase_0_T27L,beta-lactamase_0_27,TEM-1,beta-lactamase_0,P62593,0.981713,NO,27,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.905,-2.65,0.745,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.0500837,0.00306559,0.981713 beta-lactamase_2500_E102L,beta-lactamase_2500_102,TEM-1,beta-lactamase_2500,P62593,0.981718,NO,102,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.118,-3.618,1.5,,0.722,S,B,1.04,1.82,1.336,,73.08,HAH,-1.581,0.361275,0.00486633,0.981718 beta-lactamase_156_G265Y,beta-lactamase_156_265,TEM-1,beta-lactamase_156,P62593,0.981735,NO,265,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.111618,0.00811926,0.981735 beta-lactamase_H94E,beta-lactamase_94,TEM-1,beta-lactamase,P62593,0.981735,NO,94,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-2.5,-2.415,-0.085,6.1507,0.776,,B,0.63,1.24,1.176,,77.62,HBH,-1.872,0.221079,0.00389226,0.981735 beta-lactamase_S80G,beta-lactamase_80,TEM-1,beta-lactamase,P62593,0.981742,NO,80,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.029,-3.327,1.298,5.23748,0.192,H,A,0.25,0.46,2.256,,77.62,HPB,-1.44567,0.221079,0.00565569,0.981742 beta-lactamase_156_T193E,beta-lactamase_156_193,TEM-1,beta-lactamase_156,P62593,0.981759,NO,193,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.914,-3.756,1.842,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.111618,0.00482669,0.981759 kka2_1:8_T51Q,kka2_1:8_51,Kka2,kka2_1:8,P00552,0.98176,NO,51,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.199,-3.313,1.114,,0.05,E,B,0.82,-0.05,5.399,,63.64,BPA,-1.76767,0.100394,0.00628861,0.98176 kka2_1:8_T51Q,kka2_1:8_51,Kka2,kka2_1:8,P00552,0.98176,NO,51,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.199,-3.313,1.114,,0.05,E,B,0.82,-0.05,5.399,,63.64,BPA,-1.76767,0.100394,0.00628861,0.98176 kka2_1:8_W15P,kka2_1:8_15,Kka2,kka2_1:8,P00552,0.98176,NO,15,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-1.392,-4.349,2.957,,0.01,G,A,1.51,0.15,0.827,,52.27,HHH,-2.10533,0.100394,0.00585505,0.98176 kka2_1:8_W15P,kka2_1:8_15,Kka2,kka2_1:8,P00552,0.98176,NO,15,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-1.392,-4.349,2.957,,0.01,G,A,1.51,0.15,0.827,,52.27,HHH,-2.10533,0.100394,0.00585505,0.98176 Pab1_N132S,Pab1_132,Pab1,Pab1,P04147,0.981769,NO,132,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-1.079,-2.753,1.674,,0.412,S,l,,0.9,,,,BPH,-1.067,0.175299,0.000347671,0.981769 PSD95pdz3_G345M,PSD95pdz3_345,PSD95pdz3,PSD95pdz3,P31016,0.98177,NO,345,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.008,-4.612,3.604,4.32868,,,,,13.165,,,,OOO,-1.084,0.0758425,0.000771806,0.98177 beta-lactamase_39_I54Q,beta-lactamase_39_54,TEM-1,beta-lactamase_39,P62593,0.981772,NO,54,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-2.838,-2.926,0.088,,0.669,E,B,0.48,-0.14,1.349,,73.78,BHH,-2.337,0.0495842,0.00403589,0.981772 beta-lactamase_156_D33I,beta-lactamase_156_33,TEM-1,beta-lactamase_156,P62593,0.98178,NO,33,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.321,-3.065,0.744,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.111618,0.00435556,0.98178 beta-lactamase_625_I206W,beta-lactamase_625_206,TEM-1,beta-lactamase_625,P62593,0.981781,NO,206,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-2.429,-5.397,2.968,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.213352,0.00528934,0.981781 kka2_1:8_L152M,kka2_1:8_152,Kka2,kka2_1:8,P00552,0.981795,NO,152,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.521,-3.313,1.792,,0.547,.,A,0.55,1.36,1.442,,63.64,OHH,-1.162,0.100394,0.00674868,0.981795 kka2_1:8_L152M,kka2_1:8_152,Kka2,kka2_1:8,P00552,0.981795,NO,152,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.521,-3.313,1.792,,0.547,.,A,0.55,1.36,1.442,,63.64,OHH,-1.162,0.100394,0.00674868,0.981795 beta-lactamase_0_D271R,beta-lactamase_0_271,TEM-1,beta-lactamase_0,P62593,0.981806,NO,271,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.249,-3.747,2.498,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.0500837,0.00752082,0.981806 beta-lactamase_2500_K286D,beta-lactamase_2500_286,TEM-1,beta-lactamase_2500,P62593,0.981806,NO,286,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.361275,,0.981806 beta-lactamase_2500_S221V,beta-lactamase_2500_221,TEM-1,beta-lactamase_2500,P62593,0.981808,NO,221,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.754,-3.416,1.662,,0.624,H,A,0.27,-0.2,1.971,,74.48,BPH,-1.59967,0.361275,0.0046094,0.981808 beta-lactamase_156_M115L,beta-lactamase_156_115,TEM-1,beta-lactamase_156,P62593,0.981811,NO,115,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.389,-1.859,0.47,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.111618,0.0034337,0.981811 beta-lactamase_156_A148V,beta-lactamase_156_148,TEM-1,beta-lactamase_156,P62593,0.981814,NO,148,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.757,-3.631,1.874,,0.379,H,A,0.46,-0.55,3.551,,72.73,PHH,-1.40167,0.111618,0.00547053,0.981814 beta-lactamase_E145T,beta-lactamase_145,TEM-1,beta-lactamase,P62593,0.981826,NO,145,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.357,-3.565,1.208,5.38104,0.545,H,A,0.52,0.79,2.124,,77.62,BAH,-2.069,0.221079,0.00553285,0.981826 beta-lactamase_K71K,beta-lactamase_71,TEM-1,beta-lactamase,P62593,0.981826,NO,71,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-0.8,-0.8,,5.15697,,H,A,1.3,-0.99,,,,HBH,-1.209,0.221079,0.00103192,0.981826 beta-lactamase_156_G226C,beta-lactamase_156_226,TEM-1,beta-lactamase_156,P62593,0.981828,NO,226,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.461,-3.342,1.881,,0.701,T,l,0.29,-0.25,3.199,,74.48,HOH,-1.42933,0.111618,0.00665294,0.981828 beta-lactamase_156_T112C,beta-lactamase_156_112,TEM-1,beta-lactamase_156,P62593,0.981832,NO,112,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.186,-5.027,2.841,,0.921,T,A,0.22,1.06,2.87,,73.78,HPA,-1.925,0.111618,0.00531334,0.981832 beta-lactamase_2500_K30V,beta-lactamase_2500_30,TEM-1,beta-lactamase_2500,P62593,0.981833,NO,30,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-2.307,-2.807,0.5,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.361275,0.00448593,0.981833 beta-lactamase_39_A225G,beta-lactamase_39_225,TEM-1,beta-lactamase_39,P62593,0.981839,NO,225,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.845,-2.827,0.982,,1,T,B,0.46,-0.38,9.874,9.874,74.48,OHO,-1.39967,0.0495842,0.00465057,0.981839 beta-lactamase_2500_M180H,beta-lactamase_2500_180,TEM-1,beta-lactamase_2500,P62593,0.981845,NO,180,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-2.795,-4.627,1.832,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.361275,0.00552048,0.981845 beta-lactamase_39_C121S,beta-lactamase_39_121,TEM-1,beta-lactamase_39,P62593,0.981857,NO,121,C,S,CS,Special,Polar,5.07,5.68,0.61,112,121,105,-16,108.5,89,-19.5,-0.953,-3.411,2.458,,,H,A,0.46,-0.81,7.644,,63.29,HOP,-1.46767,0.0495842,0.000744322,0.981857 beta-lactamase_156_H287T,beta-lactamase_156_287,TEM-1,beta-lactamase_156,P62593,0.981859,NO,287,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,,,,,,,,,,,,,BBH,-1.111,0.111618,,0.981859 beta-lactamase_0_R41P,beta-lactamase_0_41,TEM-1,beta-lactamase_0,P62593,0.981865,NO,41,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-0.942,-3.877,2.935,,0.321,E,B,1.2,-0.07,2.68,,65.03,HBH,-1.30267,0.0500837,0.00123327,0.981865 beta-lactamase_39_G39E,beta-lactamase_39_39,TEM-1,beta-lactamase_39,P62593,0.981868,NO,39,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.864,-2.833,0.969,,0.701,T,L,0.29,0.47,1.454,,77.62,HOH,-1.53633,0.0495842,0.00487611,0.981868 beta-lactamase_2500_F70A,beta-lactamase_2500_70,TEM-1,beta-lactamase_2500,P62593,0.981873,NO,70,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.169,-3.227,2.058,,,H,A,0.58,-1.34,1.918,,63.99,PHB,-0.980667,0.361275,0.00193499,0.981873 beta-lactamase_625_E279N,beta-lactamase_625_279,TEM-1,beta-lactamase_625,P62593,0.981873,NO,279,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.213352,0.0192826,0.981873 beta-lactamase_2500_S266G,beta-lactamase_2500_266,TEM-1,beta-lactamase_2500,P62593,0.981877,NO,266,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.361275,0.0140785,0.981877 kka2_1:1_A13S,kka2_1:1_13,Kka2,kka2_1:1,P00552,0.981896,NO,13,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.248,-2.545,0.297,,0.689,G,A,0.46,0.99,25.015,25.015,92.05,OHH,-1.646,0.520039,0.00784241,0.981896 beta-lactamase_156_A40G,beta-lactamase_156_40,TEM-1,beta-lactamase_156,P62593,0.981899,NO,40,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.402,-1.32,-0.082,,0.155,S,B,0.46,0.21,1.357,,73.78,OHB,-1.40267,0.111618,0.00490026,0.981899 beta-lactamase_156_Y103F,beta-lactamase_156_103,TEM-1,beta-lactamase_156,P62593,0.981904,NO,103,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-1.33,-3.391,2.061,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.111618,0.00443048,0.981904 beta-lactamase_625_R239V,beta-lactamase_625_239,TEM-1,beta-lactamase_625,P62593,0.981904,NO,239,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.213352,0.00213852,0.981904 beta-lactamase_K213S,beta-lactamase_213,TEM-1,beta-lactamase,P62593,0.981907,NO,213,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.81,-3.351,1.541,5.63167,0.67,,A,1.59,0.29,3.924,,67.83,ABH,-1.57767,0.221079,0.00610411,0.981907 beta-lactamase_625_Q204M,beta-lactamase_625_204,TEM-1,beta-lactamase_625,P62593,0.981908,NO,204,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-1.382,-4.445,3.063,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.213352,0.00364106,0.981908 beta-lactamase_156_D252N,beta-lactamase_156_252,TEM-1,beta-lactamase_156,P62593,0.981909,NO,252,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.111618,0.00575769,0.981909 beta-lactamase_39_L197I,beta-lactamase_39_197,TEM-1,beta-lactamase_39,P62593,0.981912,NO,197,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.853,-2.968,2.115,,0.007,S,B,0.55,0.33,1.559,,60.14,HHP,-1.833,0.0495842,0.00144602,0.981912 beta-lactamase_39_T138H,beta-lactamase_39_138,TEM-1,beta-lactamase_39,P62593,0.981936,NO,138,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.506,-4.649,2.143,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.0495842,0.00487868,0.981936 beta-lactamase_39_P172R,beta-lactamase_39_172,TEM-1,beta-lactamase_39,P62593,0.981948,NO,172,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.998,-3.96,2.962,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.0495842,0.00312594,0.981948 beta-lactamase_39_T263K,beta-lactamase_39_263,TEM-1,beta-lactamase_39,P62593,0.981949,NO,263,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.0495842,0.0110582,0.981949 beta-lactamase_625_E272M,beta-lactamase_625_272,TEM-1,beta-lactamase_625,P62593,0.981949,NO,272,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.213352,0.00545371,0.981949 beta-lactamase_39_M153F,beta-lactamase_39_153,TEM-1,beta-lactamase_39,P62593,0.981952,NO,153,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-3.193,-3.944,0.751,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.0495842,0.00509109,0.981952 beta-lactamase_625_S96D,beta-lactamase_625_96,TEM-1,beta-lactamase_625,P62593,0.981961,NO,96,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.27,-3.641,1.371,,0.368,,b,0.27,0.39,5.244,,73.78,HPP,-2.019,0.213352,0.00551835,0.981961 beta-lactamase_156_M153F,beta-lactamase_156_153,TEM-1,beta-lactamase_156,P62593,0.981962,NO,153,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-3.193,-3.944,0.751,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.111618,0.00509109,0.981962 beta-lactamase_D269M,beta-lactamase_269,TEM-1,beta-lactamase,P62593,0.981965,NO,269,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.156,-4.775,2.619,5.47645,0.646,H,A,0.23,0.4,21.796,21.796,77.62,HAA,-1.96733,0.221079,0.00950944,0.981965 beta-lactamase_39_S256H,beta-lactamase_39_256,TEM-1,beta-lactamase_39,P62593,0.981968,NO,256,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.0495842,0.00710634,0.981968 Pab1_D151G,Pab1_151,Pab1,Pab1,P04147,0.981968,NO,151,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.399,-3.225,0.826,,,,,,,,,,OAH,-1.51767,0.175299,0.00228155,0.981968 beta-lactamase_2500_D113G,beta-lactamase_2500_113,TEM-1,beta-lactamase_2500,P62593,0.981974,NO,113,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.829,-2.42,0.591,,0.665,T,A,0.75,0.91,21.104,21.104,73.08,PAO,-1.703,0.361275,0.00474112,0.981974 PSD95pdz3_A370V,PSD95pdz3_370,PSD95pdz3,PSD95pdz3,P31016,0.981974,NO,370,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.307,-2.76,1.453,5.22304,,,,,17.284,,,,PHP,-1.57967,0.0758425,0.000429106,0.981974 beta-lactamase_156_E56G,beta-lactamase_156_56,TEM-1,beta-lactamase_156,P62593,0.981983,NO,56,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.043,-2.304,0.261,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.111618,0.00238534,0.981983 beta-lactamase_156_D231Y,beta-lactamase_156_231,TEM-1,beta-lactamase_156,P62593,0.981984,NO,231,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.816,-4.385,3.569,,,E,B,0.75,-1.06,2.66,,65.38,HAB,-0.994,0.111618,0.00107395,0.981984 beta-lactamase_625_D113R,beta-lactamase_625_113,TEM-1,beta-lactamase_625,P62593,0.981986,NO,113,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.829,-2.854,1.025,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.213352,0.00474112,0.981986 beta-lactamase_2500_M127W,beta-lactamase_2500_127,TEM-1,beta-lactamase_2500,P62593,0.981987,NO,127,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-2.251,-3.502,1.251,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.361275,0.00437927,0.981987 beta-lactamase_625_V214C,beta-lactamase_625_214,TEM-1,beta-lactamase_625,P62593,0.981995,NO,214,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.299,-4.725,3.426,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.213352,0.00628442,0.981995 beta-lactamase_39_R41Q,beta-lactamase_39_41,TEM-1,beta-lactamase_39,P62593,0.981997,NO,41,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-0.942,-3.498,2.556,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.0495842,0.00123327,0.981997 beta-lactamase_39_V101I,beta-lactamase_39_101,TEM-1,beta-lactamase_39,P62593,0.982001,NO,101,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.295,-2.207,0.912,,0.342,,B,0.44,0,2.96,,73.08,HHA,-1.54367,0.0495842,0.00374492,0.982001 beta-lactamase_39_L38I,beta-lactamase_39_38,TEM-1,beta-lactamase_39,P62593,0.982002,NO,38,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.343,-2.44,1.097,,0.088,H,A,0.55,0.2,17.089,17.089,64.34,PHO,-1.78033,0.0495842,0.00373244,0.982002 kka2_1:8_C209M,kka2_1:8_209,Kka2,kka2_1:8,P00552,0.98202,NO,209,C,M,CM,Special,Hydrophobic,5.07,5.74,0.67,196,121,149,28,108.5,162.9,54.4,-0.906,-4.438,3.532,,,,a,1.5,-0.89,0.391,,19.32,AOO,-0.903,0.100394,0.00260862,0.98202 kka2_1:8_C209M,kka2_1:8_209,Kka2,kka2_1:8,P00552,0.98202,NO,209,C,M,CM,Special,Hydrophobic,5.07,5.74,0.67,196,121,149,28,108.5,162.9,54.4,-0.906,-4.438,3.532,,,,a,1.5,-0.89,0.391,,19.32,AOO,-0.903,0.100394,0.00260862,0.98202 beta-lactamase_K252N,beta-lactamase_252,TEM-1,beta-lactamase,P62593,0.982022,NO,252,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.94,-2.66,0.72,5.56823,0.766,,B,1.82,1.16,21.796,21.796,67.83,OBO,-2.03333,0.221079,0.00575769,0.982022 beta-lactamase_625_V117I,beta-lactamase_625_117,TEM-1,beta-lactamase_625,P62593,0.982029,NO,117,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.53,-1.923,0.393,,,H,A,0.44,-0.34,1.23,,65.03,PHB,-1.741,0.213352,0.00467906,0.982029 beta-lactamase_39_D161E,beta-lactamase_39_161,TEM-1,beta-lactamase_39,P62593,0.982031,NO,161,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.891,-2.299,1.408,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.0495842,0.000897697,0.982031 beta-lactamase_625_T264C,beta-lactamase_625_264,TEM-1,beta-lactamase_625,P62593,0.982031,NO,264,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.213352,0.0119399,0.982031 hsp90_Q582E,hsp90_582,hsp90,hsp90,P02829,0.982035,NO,582,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-3.278,-2.818,0,4.91603,0.453,S,B,,0.67,,,,OPH,-3.249,0.368192,0.000222939,0.982035 beta-lactamase_A9C,beta-lactamase_9,TEM-1,beta-lactamase,P62593,0.982044,NO,9,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.147,-2.537,0.39,,,,,,,5.128,,72.73,HHH,-2.04267,0.221079,0.00247263,0.982044 beta-lactamase_P253C,beta-lactamase_253,TEM-1,beta-lactamase,P62593,0.982044,NO,253,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-2.253,-5.099,2.846,5.24842,0.308,,B,0.73,-0.46,2.293,,73.08,BOP,-2.10633,0.221079,0.00786358,0.982044 beta-lactamase_156_I93R,beta-lactamase_156_93,TEM-1,beta-lactamase_156,P62593,0.982053,NO,93,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.401,-4.203,2.802,,0.128,E,B,0.48,0.44,1.524,,67.83,BHB,-1.873,0.111618,0.00527066,0.982053 PSD95pdz3_N369Q,PSD95pdz3_369,PSD95pdz3,PSD95pdz3,P31016,0.982057,NO,369,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-1.572,-3.451,1.879,5.91569,,,,,24.1262,0.44,,87.71,BPH,-1.487,0.0758425,0.000608412,0.982057 beta-lactamase_625_V31T,beta-lactamase_625_31,TEM-1,beta-lactamase_625,P62593,0.982067,NO,31,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.822,-2.805,0.983,,,H,A,0.44,-0.46,2.576,,73.78,BHB,-2.03767,0.213352,0.00478065,0.982067 Pab1_E195V,Pab1_195,Pab1,Pab1,P04147,0.982067,NO,195,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.2,-3.399,2.199,,,,,,,,,,PAH,-1.72467,0.175299,0.000620107,0.982067 beta-lactamase_39_W288P,beta-lactamase_39_288,TEM-1,beta-lactamase_39,P62593,0.982072,NO,288,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,,,,,,,,,,,,,BHO,,0.0495842,,0.982072 kka2_1:4_A129V,kka2_1:4_129,Kka2,kka2_1:4,P00552,0.982072,NO,129,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.656,-3.024,1.368,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.168804,0.00726862,0.982072 beta-lactamase_625_L38I,beta-lactamase_625_38,TEM-1,beta-lactamase_625,P62593,0.982077,NO,38,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.343,-2.44,1.097,,0.088,H,A,0.55,0.2,1.986,,64.34,PHO,-1.78033,0.213352,0.00373244,0.982077 beta-lactamase_39_G281A,beta-lactamase_39_281,TEM-1,beta-lactamase_39,P62593,0.982082,NO,281,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.0495842,0.0406482,0.982082 beta-lactamase_39_A40F,beta-lactamase_39_40,TEM-1,beta-lactamase_39,P62593,0.982083,NO,40,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.402,-4.227,2.825,,0.155,S,B,0.46,0.21,0.783,,73.78,OHB,-1.40267,0.0495842,0.00490026,0.982083 beta-lactamase_625_T198K,beta-lactamase_625_198,TEM-1,beta-lactamase_625,P62593,0.982083,NO,198,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.168,-2.548,0.38,,0.489,,B,0.22,-0.13,0.37,,73.78,HPH,-1.98767,0.213352,0.004311,0.982083 beta-lactamase_156_T263L,beta-lactamase_156_263,TEM-1,beta-lactamase_156,P62593,0.982085,NO,263,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.111618,0.0110582,0.982085 beta-lactamase_156_R159C,beta-lactamase_156_159,TEM-1,beta-lactamase_156,P62593,0.982095,NO,159,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-0.94,-5.113,4.173,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.111618,0.00108472,0.982095 beta-lactamase_A246T,beta-lactamase_246,TEM-1,beta-lactamase,P62593,0.982101,NO,246,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.121,-3.507,1.386,4.78979,0.01,E,B,0.52,-1.01,1.26,,73.78,HHH,-1.55633,0.221079,0.00569458,0.982101 Pab1_D136S,Pab1_136,Pab1,Pab1,P04147,0.982109,NO,136,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.602,-3.062,1.46,,,,,,,,,,OAH,-1.42367,0.175299,0.00227029,0.982109 beta-lactamase_2500_A282Y,beta-lactamase_2500_282,TEM-1,beta-lactamase_2500,P62593,0.982112,NO,282,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.361275,0.0449821,0.982112 beta-lactamase_625_Q267T,beta-lactamase_625_267,TEM-1,beta-lactamase_625,P62593,0.982112,NO,267,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.308,-3.09,0.782,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.213352,0.0102128,0.982112 beta-lactamase_2500_S80G,beta-lactamase_2500_80,TEM-1,beta-lactamase_2500,P62593,0.982114,NO,80,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.029,-3.327,1.298,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.361275,0.00565569,0.982114 beta-lactamase_K30R,beta-lactamase_30,TEM-1,beta-lactamase,P62593,0.982114,NO,30,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-2.307,-2.265,-0.042,5.30605,0.142,H,A,1.82,-0.65,2.434,,93.01,HBH,-2.32833,0.221079,0.00448593,0.982114 beta-lactamase_39_T147H,beta-lactamase_39_147,TEM-1,beta-lactamase_39,P62593,0.982121,NO,147,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.149,-4.643,3.494,,0.281,H,A,0.22,-0.68,13.843,13.843,64.34,HPH,-1.456,0.0495842,0.00226017,0.982121 beta-lactamase_156_A183D,beta-lactamase_156_183,TEM-1,beta-lactamase_156,P62593,0.982122,NO,183,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.231,-2.686,1.455,,0.155,H,A,0.46,-0.91,23.859,23.859,77.62,HHH,-1.53367,0.111618,0.00296631,0.982122 beta-lactamase_156_A282E,beta-lactamase_156_282,TEM-1,beta-lactamase_156,P62593,0.982125,NO,282,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.111618,0.0449821,0.982125 beta-lactamase_2500_S256N,beta-lactamase_2500_256,TEM-1,beta-lactamase_2500,P62593,0.982127,NO,256,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.361275,0.00710634,0.982127 beta-lactamase_2500_G226S,beta-lactamase_2500_226,TEM-1,beta-lactamase_2500,P62593,0.982132,NO,226,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.461,-2.74,1.279,,0.701,T,l,0.29,-0.25,5.086,,74.48,HOH,-1.42933,0.361275,0.00665294,0.982132 beta-lactamase_39_I229H,beta-lactamase_39_229,TEM-1,beta-lactamase_39,P62593,0.982132,NO,229,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.267,-4.969,3.702,,0.083,E,B,0.48,-0.76,1.114,,50,HHH,-1.58767,0.0495842,0.00477249,0.982132 Pab1_A185S,Pab1_185,Pab1,Pab1,P04147,0.982134,NO,185,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.702,-2.194,0.492,,,,,,,1.756,,63.26,AHH,-1.66167,0.175299,0.00144499,0.982134 beta-lactamase_625_Y95V,beta-lactamase_625_95,TEM-1,beta-lactamase_625,P62593,0.982143,NO,95,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-1.715,-2.446,0.731,,0.122,,b,0.21,-0.37,3.355,,77.62,BHP,-2.16167,0.213352,0.00479449,0.982143 beta-lactamase_39_D207S,beta-lactamase_39_207,TEM-1,beta-lactamase_39,P62593,0.982144,NO,207,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.064,-2.656,0.592,,0.409,H,A,0.75,0.12,14.511,14.511,77.62,HAH,-1.77033,0.0495842,0.00592942,0.982144 beta-lactamase_N50I,beta-lactamase_50,TEM-1,beta-lactamase,P62593,0.982156,NO,50,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-2.979,-3.889,0.91,5.51261,0.912,T,A,1.07,1.24,1.581,,77.62,HPP,-2.134,0.221079,0.0047211,0.982156 beta-lactamase_N50V,beta-lactamase_50,TEM-1,beta-lactamase,P62593,0.982156,NO,50,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-2.979,-2.913,-0.066,5.51261,0.912,T,A,1.07,1.24,1.581,,77.62,HPP,-2.134,0.221079,0.0047211,0.982156 beta-lactamase_39_A183Y,beta-lactamase_39_183,TEM-1,beta-lactamase_39,P62593,0.982159,NO,183,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.231,-4.261,3.03,,0.155,H,A,0.46,-0.91,1.237,,77.62,HHH,-1.53367,0.0495842,0.00296631,0.982159 kka2_1:8_P109L,kka2_1:8_109,Kka2,kka2_1:8,P00552,0.982159,NO,109,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.412,-3.58,2.168,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.100394,0.0070929,0.982159 kka2_1:8_P109L,kka2_1:8_109,Kka2,kka2_1:8,P00552,0.982159,NO,109,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.412,-3.58,2.168,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.100394,0.0070929,0.982159 beta-lactamase_39_P165Q,beta-lactamase_39_165,TEM-1,beta-lactamase_39,P62593,0.982161,NO,165,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.373,-3.97,2.597,,0.203,T,A,0.52,-0.31,3.907,,73.78,AOA,-1.359,0.0495842,0.00549538,0.982161 beta-lactamase_39_H94P,beta-lactamase_39_94,TEM-1,beta-lactamase_39,P62593,0.982165,NO,94,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-2.5,-2.499,-0.001,,0.776,,B,0.17,1.24,11.583,11.583,77.62,HBH,-1.872,0.0495842,0.00389226,0.982165 beta-lactamase_625_P165L,beta-lactamase_625_165,TEM-1,beta-lactamase_625,P62593,0.982169,NO,165,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.373,-3.388,2.015,,0.203,T,A,0.52,-0.31,0.414,,73.78,AOA,-1.359,0.213352,0.00549538,0.982169 kka2_1:1_W91G,kka2_1:1_91,Kka2,kka2_1:1,P00552,0.982169,NO,91,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-1.178,-3.516,2.338,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.520039,0.00358653,0.982169 beta-lactamase_2500_H24G,beta-lactamase_2500_24,TEM-1,beta-lactamase_2500,P62593,0.982171,NO,24,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-2.481,-2.499,0.018,,,,,,,0.467,,93.01,OBO,-2.0035,0.361275,0.00238894,0.982171 beta-lactamase_2500_V29F,beta-lactamase_2500_29,TEM-1,beta-lactamase_2500,P62593,0.982174,NO,29,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-2.856,-4.364,1.508,,0.733,H,A,0.44,-0.78,1.931,,93.01,HHB,-2.24733,0.361275,0.00318969,0.982174 beta-lactamase_39_D252V,beta-lactamase_39_252,TEM-1,beta-lactamase_39,P62593,0.982185,NO,252,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.0495842,0.00575769,0.982185 beta-lactamase_S57G,beta-lactamase_57,TEM-1,beta-lactamase,P62593,0.982187,NO,57,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.918,-2.176,0.258,5.64201,0.352,E,B,0.25,-0.18,1.971,,72.73,APH,-2.29167,0.221079,0.00492804,0.982187 beta-lactamase_2500_S283M,beta-lactamase_2500_283,TEM-1,beta-lactamase_2500,P62593,0.982195,NO,283,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.361275,0.0429138,0.982195 beta-lactamase_39_L199R,beta-lactamase_39_199,TEM-1,beta-lactamase_39,P62593,0.982198,NO,199,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-2.942,-3.181,0.239,,0.832,H,A,0.55,0.42,15.504,15.504,77.62,PHH,-2.32933,0.0495842,0.0048649,0.982198 beta-lactamase_156_E102G,beta-lactamase_156_102,TEM-1,beta-lactamase_156,P62593,0.982199,NO,102,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.118,-2.728,0.61,,0.722,S,B,1.04,1.82,15.721,15.721,73.08,HAH,-1.581,0.111618,0.00486633,0.982199 beta-lactamase_625_E62S,beta-lactamase_625_62,TEM-1,beta-lactamase_625,P62593,0.982203,NO,62,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.193,-3.245,2.052,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.213352,0.00264802,0.982203 beta-lactamase_P12G,beta-lactamase_12,TEM-1,beta-lactamase,P62593,0.982204,NO,12,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-2.016,-3.349,1.333,,,,,,,2.88,,72.73,HOH,-2.05167,0.221079,0.00241653,0.982204 beta-lactamase_V31I,beta-lactamase_31,TEM-1,beta-lactamase,P62593,0.982204,NO,31,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.822,-1.838,0.016,5.43781,,H,A,2.78,-0.46,2.885,,73.78,BHB,-2.03767,0.221079,0.00478065,0.982204 beta-lactamase_39_G265Y,beta-lactamase_39_265,TEM-1,beta-lactamase_39,P62593,0.98221,NO,265,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.0495842,0.00811926,0.98221 beta-lactamase_39_R162T,beta-lactamase_39_162,TEM-1,beta-lactamase_39,P62593,0.98221,NO,162,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.016,-3.471,2.455,,0.124,S,B,1.2,-0.37,31.656,31.656,64.69,ABH,-1.25,0.0495842,0.000561334,0.98221 beta-lactamase_39_E61R,beta-lactamase_39_61,TEM-1,beta-lactamase_39,P62593,0.982211,NO,61,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.115,-3.845,1.73,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.0495842,0.00440955,0.982211 beta-lactamase_39_M127Y,beta-lactamase_39_127,TEM-1,beta-lactamase_39,P62593,0.982216,NO,127,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-2.251,-2.954,0.703,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.0495842,0.00437927,0.982216 beta-lactamase_156_D113S,beta-lactamase_156_113,TEM-1,beta-lactamase_156,P62593,0.982219,NO,113,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.829,-2.84,1.011,,0.665,T,A,0.75,0.91,2.973,,73.08,PAO,-1.703,0.111618,0.00474112,0.982219 beta-lactamase_39_G253Q,beta-lactamase_39_253,TEM-1,beta-lactamase_39,P62593,0.982219,NO,253,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.0495842,0.00786358,0.982219 beta-lactamase_39_A268S,beta-lactamase_39_268,TEM-1,beta-lactamase_39,P62593,0.982227,NO,268,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.0495842,0.0102525,0.982227 beta-lactamase_625_Q276C,beta-lactamase_625_276,TEM-1,beta-lactamase_625,P62593,0.982232,NO,276,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.213352,0.0191712,0.982232 beta-lactamase_2500_H156E,beta-lactamase_2500_156,TEM-1,beta-lactamase_2500,P62593,0.982235,NO,156,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-3.156,-2.577,-0.579,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.361275,0.00468596,0.982235 beta-lactamase_2500_E166G,beta-lactamase_2500_166,TEM-1,beta-lactamase_2500,P62593,0.982239,NO,166,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.756,-2.741,0.985,,0.508,G,A,1.04,1.05,2.124,,73.08,OAH,-1.42233,0.361275,0.00512989,0.982239 beta-lactamase_K252T,beta-lactamase_252,TEM-1,beta-lactamase,P62593,0.982241,NO,252,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.94,-3.605,1.665,5.56823,0.766,,B,1.82,1.16,21.796,21.796,67.83,OBO,-2.03333,0.221079,0.00575769,0.982241 beta-lactamase_39_R257C,beta-lactamase_39_257,TEM-1,beta-lactamase_39,P62593,0.982242,NO,257,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.0495842,0.00756629,0.982242 beta-lactamase_156_V117Q,beta-lactamase_156_117,TEM-1,beta-lactamase_156,P62593,0.982246,NO,117,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.53,-4.247,2.717,,,H,A,0.44,-0.34,1.182,,65.03,PHB,-1.741,0.111618,0.00467906,0.982246 beta-lactamase_625_R176H,beta-lactamase_625_176,TEM-1,beta-lactamase_625,P62593,0.982253,NO,176,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-0.863,-4.23,3.367,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.213352,0.00105554,0.982253 PSD95pdz3_K355W,PSD95pdz3_355,PSD95pdz3,PSD95pdz3,P31016,0.982258,NO,355,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.416,-5.004,3.588,5.56865,,,,,17.2556,,,,BBO,-1.33533,0.0758425,0.00063703,0.982258 beta-lactamase_39_L205F,beta-lactamase_39_205,TEM-1,beta-lactamase_39,P62593,0.982259,NO,205,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.922,-2.306,1.384,,,H,A,0.55,-0.46,0.846,,42.31,PHH,-1.57767,0.0495842,0.00255802,0.982259 Pab1_M189V,Pab1_189,Pab1,Pab1,P04147,0.982259,NO,189,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.406,-2.671,1.265,,0.631,E,b,,2.81,,,,OHH,-1.18,0.175299,0.000278756,0.982259 beta-lactamase_2500_I206W,beta-lactamase_2500_206,TEM-1,beta-lactamase_2500,P62593,0.98227,NO,206,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-2.429,-5.397,2.968,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.361275,0.00528934,0.98227 beta-lactamase_625_W227F,beta-lactamase_625_227,TEM-1,beta-lactamase_625,P62593,0.98227,NO,227,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-0.982,-2.609,1.627,,0.272,,B,0.47,-0.29,2.533,,74.48,OHH,-1.595,0.213352,0.00226019,0.98227 beta-lactamase_39_G39H,beta-lactamase_39_39,TEM-1,beta-lactamase_39,P62593,0.982273,NO,39,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.864,-3.359,1.495,,0.701,T,L,0.29,0.47,1.454,,77.62,HOH,-1.53633,0.0495842,0.00487611,0.982273 beta-lactamase_625_L192V,beta-lactamase_625_192,TEM-1,beta-lactamase_625,P62593,0.982289,NO,192,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.254,-1.986,0.732,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.213352,0.00558728,0.982289 beta-lactamase_156_Y103V,beta-lactamase_156_103,TEM-1,beta-lactamase_156,P62593,0.982292,NO,103,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-1.33,-3.602,2.272,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.111618,0.00443048,0.982292 beta-lactamase_39_A222W,beta-lactamase_39_222,TEM-1,beta-lactamase_39,P62593,0.9823,NO,222,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.103,-5.409,3.306,,0.233,H,A,0.46,-0.25,1.448,,77.62,PHH,-1.63733,0.0495842,0.00466094,0.9823 beta-lactamase_39_L205V,beta-lactamase_39_205,TEM-1,beta-lactamase_39,P62593,0.982322,NO,205,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.922,-2.938,2.016,,,H,A,0.55,-0.46,0.846,,42.31,PHH,-1.57767,0.0495842,0.00255802,0.982322 beta-lactamase_A77M,beta-lactamase_77,TEM-1,beta-lactamase,P62593,0.982327,NO,77,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.234,-4.524,3.29,4.75777,0.039,H,A,0.52,-0.56,1.708,,64.34,OHH,-1.294,0.221079,0.00282362,0.982327 beta-lactamase_G90W,beta-lactamase_90,TEM-1,beta-lactamase,P62593,0.982327,NO,90,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-2.091,-5.515,3.424,5.51991,0.598,T,A,0.23,0.32,1.791,,77.62,HOB,-1.52633,0.221079,0.00490273,0.982327 beta-lactamase_H156W,beta-lactamase_156,TEM-1,beta-lactamase,P62593,0.982327,NO,156,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-3.156,-5.55,2.394,6.00284,0.753,S,A,0.72,-0.6,6.456,6.456,77.62,ABH,-1.932,0.221079,0.00468596,0.982327 beta-lactamase_N152F,beta-lactamase_152,TEM-1,beta-lactamase,P62593,0.982327,NO,152,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-2.757,-4.363,1.606,5.98571,0.863,H,A,0.09,0.92,2.061,,77.62,BPH,-2.97,0.221079,0.00471429,0.982327 beta-lactamase_T198E,beta-lactamase_198,TEM-1,beta-lactamase,P62593,0.982327,NO,198,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.168,-3.379,1.211,4.9209,0.489,,B,0.69,-0.13,0.37,,73.78,HPH,-1.98767,0.221079,0.004311,0.982327 Pab1_Q194I,Pab1_194,Pab1,Pab1,P04147,0.982328,NO,194,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.179,-3.63,1.451,,,,,,,,,,OPA,-1.59767,0.175299,0.0016145,0.982328 beta-lactamase_156_S266D,beta-lactamase_156_266,TEM-1,beta-lactamase_156,P62593,0.982329,NO,266,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.111618,0.0140785,0.982329 gb1_E241A,gb1_241,gb1,gb1,P06654,0.98233,NO,241,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.672,-1.573,-0.099,,,,,,,0.344,,11.83,OAP,-1.27933,0.177985,0.00250604,0.98233 beta-lactamase_156_H151W,beta-lactamase_156_151,TEM-1,beta-lactamase_156,P62593,0.982332,NO,151,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-2.96,-5.334,2.374,,0.594,H,A,0.17,0.1,1.401,,77.62,HBP,-2.34767,0.111618,0.00216946,0.982332 beta-lactamase_156_D113Q,beta-lactamase_156_113,TEM-1,beta-lactamase_156,P62593,0.982333,NO,113,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.829,-2.873,1.044,,0.665,T,A,0.75,0.91,2.973,,73.08,PAO,-1.703,0.111618,0.00474112,0.982333 beta-lactamase_156_T107L,beta-lactamase_156_107,TEM-1,beta-lactamase_156,P62593,0.982352,NO,107,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.117,-3.237,2.12,,,G,A,0.22,-0.06,0.341,,67.83,HPA,-1.265,0.111618,0.00239347,0.982352 PSD95pdz3_L342P,PSD95pdz3_342,PSD95pdz3,PSD95pdz3,P31016,0.982354,NO,342,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.347,-3.786,2.439,5.03015,,,,,12.0762,,,,HHH,-1.428,0.0758425,0.00081112,0.982354 beta-lactamase_625_D212A,beta-lactamase_625_212,TEM-1,beta-lactamase_625,P62593,0.982359,NO,212,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.624,-2.64,1.016,,0.037,,b,0.75,-0.58,1.516,,74.48,HAB,-1.77667,0.213352,0.00644302,0.982359 beta-lactamase_G90V,beta-lactamase_90,TEM-1,beta-lactamase,P62593,0.98236,NO,90,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-2.091,-3.033,0.942,5.51991,0.598,T,A,0.23,0.32,1.791,,77.62,HOB,-1.52633,0.221079,0.00490273,0.98236 kka2_1:8_V198I,kka2_1:8_198,Kka2,kka2_1:8,P00552,0.982367,NO,198,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.719,-3.396,1.677,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.100394,0.00835002,0.982367 kka2_1:8_V198I,kka2_1:8_198,Kka2,kka2_1:8,P00552,0.982367,NO,198,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.719,-3.396,1.677,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.100394,0.00835002,0.982367 beta-lactamase_156_W288L,beta-lactamase_156_288,TEM-1,beta-lactamase_156,P62593,0.982368,NO,288,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,,,,,,,,,,,,,BHO,,0.111618,,0.982368 beta-lactamase_156_L223F,beta-lactamase_156_223,TEM-1,beta-lactamase_156,P62593,0.982373,NO,223,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.055,-2.724,1.669,,0.27,,B,0.55,0.09,1.511,,74.48,HHO,-1.35033,0.111618,0.00372793,0.982373 beta-lactamase_625_R176Y,beta-lactamase_625_176,TEM-1,beta-lactamase_625,P62593,0.982377,NO,176,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-0.863,-4.162,3.299,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.213352,0.00105554,0.982377 beta-lactamase_625_L55A,beta-lactamase_625_55,TEM-1,beta-lactamase_625,P62593,0.982384,NO,55,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.86,-2.512,0.652,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.213352,0.00403741,0.982384 kka2_1:2_S54N,kka2_1:2_54,Kka2,kka2_1:2,P00552,0.982402,NO,54,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.471,-3.168,0.697,,0.408,S,b,0.27,1.01,0.393,,71.59,HPO,-2.259,0.295029,0.00782867,0.982402 beta-lactamase_625_M66H,beta-lactamase_625_66,TEM-1,beta-lactamase_625,P62593,0.982403,NO,66,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.362,-4.866,3.504,,0.013,,A,0.55,-0.7,1.659,,73.08,OHH,-1.49567,0.213352,0.00412876,0.982403 beta-lactamase_156_P255E,beta-lactamase_156_255,TEM-1,beta-lactamase_156,P62593,0.982404,NO,255,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.111618,0.00499612,0.982404 Pab1_P135N,Pab1_135,Pab1,Pab1,P04147,0.982418,NO,135,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.457,-3.654,2.197,,,,,,,6.41,,81.8,BOA,-1.53367,0.175299,0.00148028,0.982418 beta-lactamase_625_I206E,beta-lactamase_625_206,TEM-1,beta-lactamase_625,P62593,0.982421,NO,206,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-2.429,-2.747,0.318,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.213352,0.00528934,0.982421 beta-lactamase_625_E62I,beta-lactamase_625_62,TEM-1,beta-lactamase_625,P62593,0.982436,NO,62,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.193,-4.086,2.893,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.213352,0.00264802,0.982436 kka2_1:8_L94C,kka2_1:8_94,Kka2,kka2_1:8,P00552,0.982437,NO,94,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.618,-4.788,3.17,,0.058,E,B,1.59,-0.52,2.197,,56.06,HHO,-1.612,0.100394,0.00520888,0.982437 kka2_1:8_L94C,kka2_1:8_94,Kka2,kka2_1:8,P00552,0.982437,NO,94,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.618,-4.788,3.17,,0.058,E,B,1.59,-0.52,2.197,,56.06,HHO,-1.612,0.100394,0.00520888,0.982437 beta-lactamase_39_E102F,beta-lactamase_39_102,TEM-1,beta-lactamase_39,P62593,0.982439,NO,102,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.118,-4.365,2.247,,0.722,S,B,1.04,1.82,3.87,,73.08,HAH,-1.581,0.0495842,0.00486633,0.982439 beta-lactamase_0_L248K,beta-lactamase_0_248,TEM-1,beta-lactamase_0,P62593,0.982443,NO,248,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.0500837,0.00428493,0.982443 beta-lactamase_156_I206W,beta-lactamase_156_206,TEM-1,beta-lactamase_156,P62593,0.982448,NO,206,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-2.429,-5.397,2.968,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.111618,0.00528934,0.982448 beta-lactamase_625_E102R,beta-lactamase_625_102,TEM-1,beta-lactamase_625,P62593,0.982448,NO,102,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.118,-3.801,1.683,,0.722,S,B,1.04,1.82,1.336,,73.08,HAH,-1.581,0.213352,0.00486633,0.982448 beta-lactamase_156_A278W,beta-lactamase_156_278,TEM-1,beta-lactamase_156,P62593,0.982449,NO,278,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.111618,0.0310297,0.982449 beta-lactamase_2500_H110R,beta-lactamase_2500_110,TEM-1,beta-lactamase_2500,P62593,0.98245,NO,110,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-1.706,-2.008,0.302,,0.341,G,a,0.17,1.08,31.31,31.31,64.69,BBH,-1.73333,0.361275,0.00441499,0.98245 beta-lactamase_39_L137T,beta-lactamase_39_137,TEM-1,beta-lactamase_39,P62593,0.982453,NO,137,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.03,-3.486,2.456,,,H,A,0.55,-0.38,0.674,,42.31,HHP,-1.58933,0.0495842,0.00278599,0.982453 beta-lactamase_0_I45V,beta-lactamase_0_45,TEM-1,beta-lactamase_0,P62593,0.982454,NO,45,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-2.421,-2.178,-0.243,,,E,B,0.48,-0.3,1.375,,77.62,HHA,-2.30267,0.0500837,0.00452842,0.982454 kka2_1:4_L243R,kka2_1:4_243,Kka2,kka2_1:4,P00552,0.982456,NO,243,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-2.651,-2.013,-0.638,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.168804,0.00884927,0.982456 beta-lactamase_39_L28G,beta-lactamase_39_28,TEM-1,beta-lactamase_39,P62593,0.982463,NO,28,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.579,-3.602,2.023,,0.277,H,A,0.55,-0.16,3.262,,93.01,PHH,-2.11333,0.0495842,0.00359321,0.982463 beta-lactamase_156_L111T,beta-lactamase_156_111,TEM-1,beta-lactamase_156,P62593,0.982468,NO,111,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.76,-2.765,1.005,,0.328,T,A,0.55,0.93,2.26,,64.34,BHP,-1.884,0.111618,0.00480671,0.982468 beta-lactamase_2500_D271V,beta-lactamase_2500_271,TEM-1,beta-lactamase_2500,P62593,0.982474,NO,271,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.361275,0.00752082,0.982474 beta-lactamase_156_S221W,beta-lactamase_156_221,TEM-1,beta-lactamase_156,P62593,0.982479,NO,221,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.754,-5.418,3.664,,0.624,H,A,0.27,-0.2,17.729,17.729,74.48,BPH,-1.59967,0.111618,0.0046094,0.982479 beta-lactamase_156_I93N,beta-lactamase_156_93,TEM-1,beta-lactamase_156,P62593,0.982492,NO,93,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.401,-4.175,2.774,,0.128,E,B,0.48,0.44,1.524,,67.83,BHB,-1.873,0.111618,0.00527066,0.982492 beta-lactamase_156_S283E,beta-lactamase_156_283,TEM-1,beta-lactamase_156,P62593,0.982492,NO,283,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.111618,0.0429138,0.982492 beta-lactamase_625_V82M,beta-lactamase_625_82,TEM-1,beta-lactamase_625,P62593,0.982494,NO,82,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.325,-4.274,2.949,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.213352,0.00397046,0.982494 beta-lactamase_625_H287F,beta-lactamase_625_287,TEM-1,beta-lactamase_625,P62593,0.982499,NO,287,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,,,,,,,,,,,,,BBH,-1.111,0.213352,,0.982499 beta-lactamase_39_I229K,beta-lactamase_39_229,TEM-1,beta-lactamase_39,P62593,0.982502,NO,229,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.267,-3.862,2.595,,0.083,E,B,0.48,-0.76,1.114,,50,HHH,-1.58767,0.0495842,0.00477249,0.982502 beta-lactamase_P12V,beta-lactamase_12,TEM-1,beta-lactamase,P62593,0.982503,NO,12,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-2.016,-3.236,1.22,,,,,,,2.88,,72.73,HOH,-2.05167,0.221079,0.00241653,0.982503 beta-lactamase_39_G226N,beta-lactamase_39_226,TEM-1,beta-lactamase_39,P62593,0.982505,NO,226,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.461,-2.628,1.167,,0.701,T,l,0.29,-0.25,23.034,23.034,74.48,HOH,-1.42933,0.0495842,0.00665294,0.982505 beta-lactamase_39_L219Q,beta-lactamase_39_219,TEM-1,beta-lactamase_39,P62593,0.982508,NO,219,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.313,-4.292,2.979,,,I,A,0.55,-0.51,19.842,19.842,74.48,HHB,-1.21533,0.0495842,0.00664345,0.982508 beta-lactamase_39_L100Q,beta-lactamase_39_100,TEM-1,beta-lactamase_39,P62593,0.982509,NO,100,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.218,-4.259,3.041,,0.343,,B,0.55,0.13,8.311,,63.29,AHH,-1.23467,0.0495842,0.00413885,0.982509 gb1_K230Q,gb1_230,gb1,gb1,P06654,0.982509,NO,230,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.701,-3.46,1.759,,,,,,,0.166,,11.83,HBH,-1.52867,0.177985,0.00331703,0.982509 beta-lactamase_39_D271L,beta-lactamase_39_271,TEM-1,beta-lactamase_39,P62593,0.982516,NO,271,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.0495842,0.00752082,0.982516 beta-lactamase_156_Y95G,beta-lactamase_156_95,TEM-1,beta-lactamase_156,P62593,0.982527,NO,95,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-1.715,-3.781,2.066,,0.122,,b,0.21,-0.37,2.341,,77.62,BHP,-2.16167,0.111618,0.00479449,0.982527 beta-lactamase_R189G,beta-lactamase_189,TEM-1,beta-lactamase,P62593,0.982527,NO,189,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.844,-3.504,1.66,5.74877,0.278,H,A,0.68,1.01,1.512,,72.73,HBB,-1.668,0.221079,0.0050699,0.982527 beta-lactamase_A246F,beta-lactamase_246,TEM-1,beta-lactamase,P62593,0.982531,NO,246,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.121,-2.727,0.606,4.78979,0.01,E,B,0.52,-1.01,1.26,,73.78,HHH,-1.55633,0.221079,0.00569458,0.982531 beta-lactamase_2500_L223C,beta-lactamase_2500_223,TEM-1,beta-lactamase_2500,P62593,0.982535,NO,223,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.055,-4.721,3.666,,0.27,,B,0.55,0.09,1.334,,74.48,HHO,-1.35033,0.361275,0.00372793,0.982535 beta-lactamase_156_W163F,beta-lactamase_156_163,TEM-1,beta-lactamase_156,P62593,0.982542,NO,163,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-1.843,-3.138,1.295,,0.467,,B,0.47,-0.5,15.095,15.095,63.99,BHA,-1.269,0.111618,0.00418955,0.982542 beta-lactamase_2500_E166C,beta-lactamase_2500_166,TEM-1,beta-lactamase_2500,P62593,0.982542,NO,166,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.756,-5.069,3.313,,0.508,G,A,1.04,1.05,2.124,,73.08,OAH,-1.42233,0.361275,0.00512989,0.982542 beta-lactamase_156_Q204H,beta-lactamase_156_204,TEM-1,beta-lactamase_156,P62593,0.982546,NO,204,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-1.382,-3.09,1.708,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.111618,0.00364106,0.982546 beta-lactamase_39_A215E,beta-lactamase_39_215,TEM-1,beta-lactamase_39,P62593,0.982551,NO,215,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.503,-3.531,2.028,,,,a,0.46,-0.93,0.494,,74.48,HHO,-1.42633,0.0495842,0.00544007,0.982551 kka2_1:4_L107M,kka2_1:4_107,Kka2,kka2_1:4,P00552,0.982551,NO,107,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.238,-2.856,1.618,,0.197,.,B,0.55,-1.1,0.398,,71.59,BHH,-2.143,0.168804,0.00561937,0.982551 beta-lactamase_39_S283P,beta-lactamase_39_283,TEM-1,beta-lactamase_39,P62593,0.982553,NO,283,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.0495842,0.0429138,0.982553 beta-lactamase_156_E62N,beta-lactamase_156_62,TEM-1,beta-lactamase_156,P62593,0.982554,NO,62,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.193,-3.541,2.348,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.111618,0.00264802,0.982554 PSD95pdz3_Y392T,PSD95pdz3_392,PSD95pdz3,PSD95pdz3,P31016,0.982559,NO,392,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-1.437,-3.328,1.891,5.20337,,,,,11.725,,,,PHB,-1.51733,0.0758425,0.000935211,0.982559 beta-lactamase_156_T147N,beta-lactamase_156_147,TEM-1,beta-lactamase_156,P62593,0.982561,NO,147,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.149,-2.415,1.266,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.111618,0.00226017,0.982561 beta-lactamase_39_L136C,beta-lactamase_39_136,TEM-1,beta-lactamase_39,P62593,0.982566,NO,136,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.232,-4.751,3.519,,,H,A,0.55,-0.34,0.336,,48.95,HHH,-1.088,0.0495842,0.00442304,0.982566 beta-lactamase_2500_V157E,beta-lactamase_2500_157,TEM-1,beta-lactamase_2500,P62593,0.982567,NO,157,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.751,-3.68,1.929,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.361275,0.00506849,0.982567 beta-lactamase_T126G,beta-lactamase_126,TEM-1,beta-lactamase,P62593,0.982569,NO,126,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.122,-2.22,1.098,4.82694,0.05,H,A,0.3,-0.05,1.14,,44.41,HPH,-1.60467,0.221079,0.00244552,0.982569 beta-lactamase_39_D231A,beta-lactamase_39_231,TEM-1,beta-lactamase_39,P62593,0.982571,NO,231,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.816,-3.3,2.484,,,E,B,0.75,-1.06,0.462,,65.38,HAB,-0.994,0.0495842,0.00107395,0.982571 beta-lactamase_E61S,beta-lactamase_61,TEM-1,beta-lactamase,P62593,0.982575,NO,61,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.115,-2.688,0.573,6.29701,0.775,T,a,0.52,1.29,1.975,,77.62,OAA,-1.92567,0.221079,0.00440955,0.982575 beta-lactamase_39_T263C,beta-lactamase_39_263,TEM-1,beta-lactamase_39,P62593,0.982578,NO,263,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.0495842,0.0110582,0.982578 beta-lactamase_0_S57Y,beta-lactamase_0_57,TEM-1,beta-lactamase_0,P62593,0.982586,NO,57,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.918,-4.294,2.376,,0.352,E,B,0.27,-0.18,1.454,,72.73,APH,-2.29167,0.0500837,0.00492804,0.982586 beta-lactamase_625_D83S,beta-lactamase_625_83,TEM-1,beta-lactamase_625,P62593,0.982587,NO,83,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.066,-2.542,1.476,,0.354,H,A,0.75,0.22,0.239,,48.95,HAH,-1.34733,0.213352,0.00205968,0.982587 beta-lactamase_156_G265Q,beta-lactamase_156_265,TEM-1,beta-lactamase_156,P62593,0.982593,NO,265,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-2.58,-2.659,0.079,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.111618,0.00811926,0.982593 beta-lactamase_156_S221Y,beta-lactamase_156_221,TEM-1,beta-lactamase_156,P62593,0.982593,NO,221,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.754,-4.278,2.524,,0.624,H,A,0.27,-0.2,17.729,17.729,74.48,BPH,-1.59967,0.111618,0.0046094,0.982593 beta-lactamase_2500_L199D,beta-lactamase_2500_199,TEM-1,beta-lactamase_2500,P62593,0.982606,NO,199,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-2.942,-3.009,0.067,,0.832,H,A,0.55,0.42,15.504,15.504,77.62,PHH,-2.32933,0.361275,0.0048649,0.982606 beta-lactamase_156_D83A,beta-lactamase_156_83,TEM-1,beta-lactamase_156,P62593,0.982607,NO,83,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.066,-3.208,2.142,,0.354,H,A,0.75,0.22,1.281,,48.95,HAH,-1.34733,0.111618,0.00205968,0.982607 beta-lactamase_S80T,beta-lactamase_80,TEM-1,beta-lactamase,P62593,0.982608,NO,80,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.029,-2.845,0.816,5.23748,0.192,H,A,0.25,0.46,2.256,,77.62,HPB,-1.44567,0.221079,0.00565569,0.982608 beta-lactamase_0_P105E,beta-lactamase_0_105,TEM-1,beta-lactamase_0,P62593,0.98262,NO,105,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.813,-3.437,2.624,,0.226,T,A,0.52,0.8,3.48,,63.29,POH,-1.01533,0.0500837,0.0011981,0.98262 beta-lactamase_K109V,beta-lactamase_109,TEM-1,beta-lactamase,P62593,0.982624,NO,109,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.734,-3.727,1.993,6.05842,0.787,G,A,1.82,2.21,21.623,21.623,72.73,ABB,-1.63333,0.221079,0.00462493,0.982624 beta-lactamase_P60C,beta-lactamase_60,TEM-1,beta-lactamase,P62593,0.982624,NO,60,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-2.469,-4.889,2.42,5.51353,0.256,T,A,0.73,-0.56,3.653,,77.62,BOA,-1.97633,0.221079,0.00521318,0.982624 beta-lactamase_156_K254V,beta-lactamase_156_254,TEM-1,beta-lactamase_156,P62593,0.982625,NO,254,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.111618,0.00369,0.982625 beta-lactamase_2500_E56D,beta-lactamase_2500_56,TEM-1,beta-lactamase_2500,P62593,0.982625,NO,56,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.043,-3.248,1.205,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.361275,0.00238534,0.982625 beta-lactamase_Q88L,beta-lactamase_88,TEM-1,beta-lactamase,P62593,0.982632,NO,88,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.086,-3.504,1.418,5.8056,0.807,,B,0.12,2.03,1.84,,77.62,APH,-1.53433,0.221079,0.00504167,0.982632 kka2_1:2_A168N,kka2_1:2_168,Kka2,kka2_1:2,P00552,0.982639,NO,168,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.989,-3.164,1.175,,0.67,H,A,0.46,0.15,25.546,25.546,64.39,OHA,-2.12933,0.295029,0.00806773,0.982639 beta-lactamase_2500_S221N,beta-lactamase_2500_221,TEM-1,beta-lactamase_2500,P62593,0.982645,NO,221,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.754,-3.696,1.942,,0.624,H,A,0.27,-0.2,1.971,,74.48,BPH,-1.59967,0.361275,0.0046094,0.982645 beta-lactamase_39_N173K,beta-lactamase_39_173,TEM-1,beta-lactamase_39,P62593,0.982659,NO,173,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-2.663,-2.711,0.048,,1.044,T,l,0.61,1.25,1.426,,77.62,OPA,-1.46633,0.0495842,0.0033769,0.982659 beta-lactamase_2500_Q88F,beta-lactamase_2500_88,TEM-1,beta-lactamase_2500,P62593,0.982663,NO,88,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.086,-4.377,2.291,,0.807,,B,0.64,2.03,1.84,,77.62,APH,-1.53433,0.361275,0.00504167,0.982663 beta-lactamase_2500_E166K,beta-lactamase_2500_166,TEM-1,beta-lactamase_2500,P62593,0.982666,NO,166,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.756,-2.625,0.869,,0.508,G,A,1.04,1.05,2.124,,73.08,OAH,-1.42233,0.361275,0.00512989,0.982666 beta-lactamase_39_Q267K,beta-lactamase_39_267,TEM-1,beta-lactamase_39,P62593,0.982674,NO,267,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.0495842,0.0102128,0.982674 Pab1_K180M,Pab1_180,Pab1,Pab1,P04147,0.982676,NO,180,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.945,-4.548,2.603,,,,,,,,,,HBA,-1.575,0.175299,0.00295933,0.982676 beta-lactamase_39_A170V,beta-lactamase_39_170,TEM-1,beta-lactamase_39,P62593,0.982689,NO,170,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.237,-2.64,1.403,,0.126,,L,0.46,-0.35,3.7,,64.69,AHH,-1.63267,0.0495842,0.00431903,0.982689 beta-lactamase_625_L38S,beta-lactamase_625_38,TEM-1,beta-lactamase_625,P62593,0.98269,NO,38,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.343,-2.597,1.254,,0.088,H,A,0.55,0.2,1.986,,64.34,PHO,-1.78033,0.213352,0.00373244,0.98269 beta-lactamase_625_E279A,beta-lactamase_625_279,TEM-1,beta-lactamase_625,P62593,0.982691,NO,279,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.213352,0.0192826,0.982691 beta-lactamase_156_M153L,beta-lactamase_156_153,TEM-1,beta-lactamase_156,P62593,0.982692,NO,153,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-3.193,-1.8,-1.393,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.111618,0.00509109,0.982692 beta-lactamase_2500_W163I,beta-lactamase_2500_163,TEM-1,beta-lactamase_2500,P62593,0.982694,NO,163,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-1.843,-3.136,1.293,,0.467,,B,0.47,-0.5,32.624,32.624,63.99,BHA,-1.269,0.361275,0.00418955,0.982694 beta-lactamase_A246Y,beta-lactamase_246,TEM-1,beta-lactamase,P62593,0.982695,NO,246,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.121,-4.018,1.897,4.78979,0.01,E,B,0.52,-1.01,1.26,,73.78,HHH,-1.55633,0.221079,0.00569458,0.982695 kka2_1:8_A255L,kka2_1:8_255,Kka2,kka2_1:8,P00552,0.982697,NO,255,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.715,-3.015,1.3,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.100394,0.0126809,0.982697 kka2_1:8_A255L,kka2_1:8_255,Kka2,kka2_1:8,P00552,0.982697,NO,255,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.715,-3.015,1.3,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.100394,0.0126809,0.982697 beta-lactamase_156_E56V,beta-lactamase_156_56,TEM-1,beta-lactamase_156,P62593,0.982702,NO,56,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.043,-3.397,1.354,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.111618,0.00238534,0.982702 beta-lactamase_625_R176A,beta-lactamase_625_176,TEM-1,beta-lactamase_625,P62593,0.982706,NO,176,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-0.863,-3.078,2.215,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.213352,0.00105554,0.982706 beta-lactamase_39_R81M,beta-lactamase_39_81,TEM-1,beta-lactamase_39,P62593,0.98271,NO,81,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.466,-4.579,3.113,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.0495842,0.00499763,0.98271 kka2_1:4_L19M,kka2_1:4_19,Kka2,kka2_1:4,P00552,0.98271,NO,19,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.254,-4.18,2.926,,0.08,T,A,1.59,-0.26,2.645,,65.53,BHH,-2.221,0.168804,0.00620703,0.98271 beta-lactamase_625_D161A,beta-lactamase_625_161,TEM-1,beta-lactamase_625,P62593,0.982711,NO,161,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.891,-3.235,2.344,,0.341,,A,0.75,-0.52,4.655,,61.19,HAB,-0.961333,0.213352,0.000897697,0.982711 beta-lactamase_2500_G39K,beta-lactamase_2500_39,TEM-1,beta-lactamase_2500,P62593,0.982714,NO,39,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.864,-2.703,0.839,,0.701,T,L,0.29,0.47,29.926,29.926,77.62,HOH,-1.53633,0.361275,0.00487611,0.982714 kka2_1:8_T85P,kka2_1:8_85,Kka2,kka2_1:8,P00552,0.982721,NO,85,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.165,-4.057,1.892,,0.576,E,B,0.22,1.39,22.154,22.154,71.59,HPA,-2.10133,0.100394,0.00634493,0.982721 kka2_1:8_T85P,kka2_1:8_85,Kka2,kka2_1:8,P00552,0.982721,NO,85,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.165,-4.057,1.892,,0.576,E,B,0.22,1.39,22.154,22.154,71.59,HPA,-2.10133,0.100394,0.00634493,0.982721 beta-lactamase_625_D113H,beta-lactamase_625_113,TEM-1,beta-lactamase_625,P62593,0.982723,NO,113,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.829,-4.704,2.875,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.213352,0.00474112,0.982723 beta-lactamase_39_P105Q,beta-lactamase_39_105,TEM-1,beta-lactamase_39,P62593,0.982725,NO,105,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.813,-3.897,3.084,,0.226,T,A,0.52,0.8,1.222,,63.29,POH,-1.01533,0.0495842,0.0011981,0.982725 beta-lactamase_39_A182I,beta-lactamase_39_182,TEM-1,beta-lactamase_39,P62593,0.982742,NO,182,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.777,-3.851,2.074,,0.136,H,A,0.46,-0.66,2.598,,93.01,OHH,-1.27367,0.0495842,0.00559099,0.982742 beta-lactamase_2500_G253Q,beta-lactamase_2500_253,TEM-1,beta-lactamase_2500,P62593,0.98275,NO,253,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.361275,0.00786358,0.98275 beta-lactamase_156_G226A,beta-lactamase_156_226,TEM-1,beta-lactamase_156,P62593,0.982771,NO,226,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.461,-2.638,1.177,,0.701,T,l,0.29,-0.25,3.199,,74.48,HOH,-1.42933,0.111618,0.00665294,0.982771 beta-lactamase_A200Y,beta-lactamase_200,TEM-1,beta-lactamase,P62593,0.982777,NO,200,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.878,-4.399,2.521,5.19406,0.757,H,A,0.47,-0.19,0.436,,77.62,HHP,-2.001,0.221079,0.0060056,0.982777 beta-lactamase_L188M,beta-lactamase_188,TEM-1,beta-lactamase,P62593,0.982777,NO,188,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.166,-2.706,1.54,5.55434,,H,A,1.07,-0.3,1.574,,60.14,PHB,-1.47033,0.221079,0.00295687,0.982777 beta-lactamase_T126E,beta-lactamase_126,TEM-1,beta-lactamase,P62593,0.982777,NO,126,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.122,-3.395,2.273,4.82694,0.05,H,A,0.3,-0.05,1.14,,44.41,HPH,-1.60467,0.221079,0.00244552,0.982777 beta-lactamase_2500_E26L,beta-lactamase_2500_26,TEM-1,beta-lactamase_2500,P62593,0.982781,NO,26,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.454,-2.726,0.272,,0.54,H,A,1.04,0.98,0.49,,93.01,OAP,-1.96167,0.361275,0.00297948,0.982781 kka2_1:8_Y22C,kka2_1:8_22,Kka2,kka2_1:8,P00552,0.982783,NO,22,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-1.583,-3.399,1.816,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.100394,0.00598977,0.982783 kka2_1:8_Y22C,kka2_1:8_22,Kka2,kka2_1:8,P00552,0.982783,NO,22,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-1.583,-3.399,1.816,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.100394,0.00598977,0.982783 beta-lactamase_625_E279F,beta-lactamase_625_279,TEM-1,beta-lactamase_625,P62593,0.982797,NO,279,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.213352,0.0192826,0.982797 beta-lactamase_2500_E145V,beta-lactamase_2500_145,TEM-1,beta-lactamase_2500,P62593,0.982801,NO,145,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.357,-3.665,1.308,,0.545,H,A,1.04,0.79,2.124,,77.62,BAH,-2.069,0.361275,0.00553285,0.982801 beta-lactamase_2500_V117L,beta-lactamase_2500_117,TEM-1,beta-lactamase_2500,P62593,0.982805,NO,117,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.53,-1.606,0.076,,,H,A,0.44,-0.34,1.23,,65.03,PHB,-1.741,0.361275,0.00467906,0.982805 beta-lactamase_39_R162C,beta-lactamase_39_162,TEM-1,beta-lactamase_39,P62593,0.982805,NO,162,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.016,-5.08,4.064,,0.124,S,B,1.2,-0.37,31.656,31.656,64.69,ABH,-1.25,0.0495842,0.000561334,0.982805 beta-lactamase_156_S51G,beta-lactamase_156_51,TEM-1,beta-lactamase_156,P62593,0.982809,NO,51,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.526,-2.569,1.043,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.111618,0.00504821,0.982809 beta-lactamase_156_T116A,beta-lactamase_156_116,TEM-1,beta-lactamase_156,P62593,0.982811,NO,116,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.28,-2.469,1.189,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.111618,0.00336175,0.982811 beta-lactamase_39_A170W,beta-lactamase_39_170,TEM-1,beta-lactamase_39,P62593,0.982813,NO,170,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.237,-5.233,3.996,,0.126,,L,0.46,-0.35,3.7,,64.69,AHH,-1.63267,0.0495842,0.00431903,0.982813 beta-lactamase_39_K53W,beta-lactamase_39_53,TEM-1,beta-lactamase_39,P62593,0.982815,NO,53,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-2.313,-2.612,0.299,,0.589,,B,2.34,1.15,15.633,15.633,77.62,OBH,-2.1,0.0495842,0.00383383,0.982815 beta-lactamase_156_D177C,beta-lactamase_156_177,TEM-1,beta-lactamase_156,P62593,0.982817,NO,177,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.967,-5.073,4.106,,0.006,T,L,0.75,-1.02,2.072,,64.69,BAP,-0.873667,0.111618,0.000864022,0.982817 beta-lactamase_2500_L100I,beta-lactamase_2500_100,TEM-1,beta-lactamase_2500,P62593,0.982823,NO,100,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.218,-1.863,0.645,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.361275,0.00413885,0.982823 beta-lactamase_39_I54W,beta-lactamase_39_54,TEM-1,beta-lactamase_39,P62593,0.982825,NO,54,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-2.838,-5.452,2.614,,0.669,E,B,0.48,-0.14,1.349,,73.78,BHH,-2.337,0.0495842,0.00403589,0.982825 beta-lactamase_156_D174I,beta-lactamase_156_174,TEM-1,beta-lactamase_156,P62593,0.982831,NO,174,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.738,-4.01,3.272,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.111618,0.00125633,0.982831 beta-lactamase_625_D33M,beta-lactamase_625_33,TEM-1,beta-lactamase_625,P62593,0.982831,NO,33,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.321,-4.607,2.286,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.213352,0.00435556,0.982831 beta-lactamase_2500_E46A,beta-lactamase_2500_46,TEM-1,beta-lactamase_2500,P62593,0.982842,NO,46,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.94,-2.586,0.646,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.361275,0.00427568,0.982842 Pab1_K164T,Pab1_164,Pab1,Pab1,P04147,0.982843,NO,164,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-2.298,-3.374,1.076,,,,,,,,,,OBP,-1.41767,0.175299,0.00255241,0.982843 Pab1_K164I,Pab1_164,Pab1,Pab1,P04147,0.982849,NO,164,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-2.298,-2.758,0.46,,,,,,,,,,OBP,-1.41767,0.175299,0.00255241,0.982849 beta-lactamase_625_A170E,beta-lactamase_625_170,TEM-1,beta-lactamase_625,P62593,0.982853,NO,170,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.237,-3.626,2.389,,0.126,,L,0.46,-0.35,3.626,,64.69,AHH,-1.63267,0.213352,0.00431903,0.982853 beta-lactamase_625_H156E,beta-lactamase_625_156,TEM-1,beta-lactamase_625,P62593,0.982853,NO,156,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-3.156,-2.577,-0.579,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.213352,0.00468596,0.982853 beta-lactamase_156_D113H,beta-lactamase_156_113,TEM-1,beta-lactamase_156,P62593,0.982866,NO,113,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.829,-4.704,2.875,,0.665,T,A,0.75,0.91,2.973,,73.08,PAO,-1.703,0.111618,0.00474112,0.982866 gb1_D262F,gb1_262,gb1,gb1,P06654,0.982867,NO,262,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-3.132,-4.082,0.95,,,,,,,1.304,,45.54,PAP,-2.05233,0.177985,0.00413102,0.982867 gb1_N234V,gb1_234,gb1,gb1,P06654,0.982867,NO,234,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-2.055,-3.491,1.436,,,,,,,1.235,,45.54,HPO,-2.05067,0.177985,0.00242189,0.982867 beta-lactamase_156_R176D,beta-lactamase_156_176,TEM-1,beta-lactamase_156,P62593,0.982875,NO,176,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-0.863,-3.694,2.831,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.111618,0.00105554,0.982875 beta-lactamase_2500_D33M,beta-lactamase_2500_33,TEM-1,beta-lactamase_2500,P62593,0.982888,NO,33,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.321,-4.607,2.286,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.361275,0.00435556,0.982888 beta-lactamase_156_I206Q,beta-lactamase_156_206,TEM-1,beta-lactamase_156,P62593,0.982889,NO,206,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-2.429,-2.554,0.125,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.111618,0.00528934,0.982889 Pab1_F146I,Pab1_146,Pab1,Pab1,P04147,0.982896,NO,146,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.149,-3.152,2.003,,0.006,H,A,,0.75,,,,PHP,-1.161,0.175299,0.000329265,0.982896 beta-lactamase_156_N168G,beta-lactamase_156_168,TEM-1,beta-lactamase_156,P62593,0.982898,NO,168,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-1.029,-3.01,1.981,,0.113,G,A,0.61,-0.4,1.014,,44.41,HPA,-1.13233,0.111618,0.00288667,0.982898 beta-lactamase_625_I171N,beta-lactamase_625_171,TEM-1,beta-lactamase_625,P62593,0.982915,NO,171,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-2.431,-3.904,1.473,,0.361,,B,0.48,0.53,3.869,,77.62,HHO,-1.55533,0.213352,0.00623355,0.982915 beta-lactamase_156_G226Q,beta-lactamase_156_226,TEM-1,beta-lactamase_156,P62593,0.982922,NO,226,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.461,-3.959,2.498,,0.701,T,l,0.29,-0.25,3.199,,74.48,HOH,-1.42933,0.111618,0.00665294,0.982922 beta-lactamase_L223I,beta-lactamase_223,TEM-1,beta-lactamase,P62593,0.982923,NO,223,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.055,-2.996,1.941,5.42318,0.27,,B,1.3,0.09,1.511,,74.48,HHO,-1.35033,0.221079,0.00372793,0.982923 beta-lactamase_156_N50P,beta-lactamase_156_50,TEM-1,beta-lactamase_156,P62593,0.982924,NO,50,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-2.979,-3.95,0.971,,0.912,T,A,0.61,1.24,13.295,13.295,77.62,HPP,-2.134,0.111618,0.0047211,0.982924 beta-lactamase_156_Q276P,beta-lactamase_156_276,TEM-1,beta-lactamase_156,P62593,0.982924,NO,276,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.111618,0.0191712,0.982924 beta-lactamase_2500_T131A,beta-lactamase_2500_131,TEM-1,beta-lactamase_2500,P62593,0.982925,NO,131,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.328,-2.085,0.757,,,H,A,0.22,-0.69,3.048,,67.48,PPH,-1.00867,0.361275,0.00345886,0.982925 PSD95pdz3_L342C,PSD95pdz3_342,PSD95pdz3,PSD95pdz3,P31016,0.98293,NO,342,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.347,-4.319,2.972,5.03015,,,,,12.0762,,,,HHH,-1.428,0.0758425,0.00081112,0.98293 beta-lactamase_39_N152M,beta-lactamase_39_152,TEM-1,beta-lactamase_39,P62593,0.982931,NO,152,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-2.757,-4.737,1.98,,0.863,H,A,0.61,0.92,4.038,,77.62,BPH,-2.97,0.0495842,0.00471429,0.982931 beta-lactamase_156_P255R,beta-lactamase_156_255,TEM-1,beta-lactamase_156,P62593,0.982932,NO,255,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-2.266,-4.188,1.922,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.111618,0.00499612,0.982932 beta-lactamase_K30L,beta-lactamase_30,TEM-1,beta-lactamase,P62593,0.982934,NO,30,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-2.307,-3.404,1.097,5.30605,0.142,H,A,1.82,-0.65,2.434,,93.01,HBH,-2.32833,0.221079,0.00448593,0.982934 beta-lactamase_L55Y,beta-lactamase_55,TEM-1,beta-lactamase,P62593,0.982934,NO,55,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.86,-3.812,1.952,,0.372,E,A,1.07,-0.36,1.423,,63.99,HHA,-2.247,0.221079,0.00403741,0.982934 beta-lactamase_0_I93G,beta-lactamase_0_93,TEM-1,beta-lactamase_0,P62593,0.982948,NO,93,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.401,-3.805,2.404,,0.128,E,B,0.48,0.44,1.266,,67.83,BHB,-1.873,0.0500837,0.00527066,0.982948 beta-lactamase_156_S221L,beta-lactamase_156_221,TEM-1,beta-lactamase_156,P62593,0.982948,NO,221,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.754,-3.35,1.596,,0.624,H,A,0.27,-0.2,17.729,17.729,74.48,BPH,-1.59967,0.111618,0.0046094,0.982948 beta-lactamase_D250Y,beta-lactamase_250,TEM-1,beta-lactamase,P62593,0.98295,NO,250,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.335,-4.381,2.046,5.72026,0.89,T,L,0.23,1.53,24.737,24.737,66.08,OAO,-1.85133,0.221079,0.00550899,0.98295 beta-lactamase_2500_S221M,beta-lactamase_2500_221,TEM-1,beta-lactamase_2500,P62593,0.982952,NO,221,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.754,-4.595,2.841,,0.624,H,A,0.27,-0.2,1.971,,74.48,BPH,-1.59967,0.361275,0.0046094,0.982952 beta-lactamase_156_R63E,beta-lactamase_156_63,TEM-1,beta-lactamase_156,P62593,0.982967,NO,63,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-0.943,-3.298,2.355,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.111618,0.00126938,0.982967 beta-lactamase_39_P255W,beta-lactamase_39_255,TEM-1,beta-lactamase_39,P62593,0.982967,NO,255,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.0495842,0.00499612,0.982967 beta-lactamase_625_V101R,beta-lactamase_625_101,TEM-1,beta-lactamase_625,P62593,0.982968,NO,101,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.295,-4.134,2.839,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.213352,0.00374492,0.982968 beta-lactamase_625_S221H,beta-lactamase_625_221,TEM-1,beta-lactamase_625,P62593,0.982969,NO,221,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.754,-4.673,2.919,,0.624,H,A,0.27,-0.2,1.495,,74.48,BPH,-1.59967,0.213352,0.0046094,0.982969 beta-lactamase_0_A247G,beta-lactamase_0_247,TEM-1,beta-lactamase_0,P62593,0.982974,NO,247,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.0500837,0.00611275,0.982974 beta-lactamase_156_K213T,beta-lactamase_156_213,TEM-1,beta-lactamase_156,P62593,0.982975,NO,213,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.81,-2.431,0.621,,0.67,,A,2.34,0.29,3.924,,67.83,ABH,-1.57767,0.111618,0.00610411,0.982975 PSD95pdz3_I377Q,PSD95pdz3_377,PSD95pdz3,PSD95pdz3,P31016,0.982976,NO,377,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.873,-4.024,2.151,4.9532,,,,,19.185,2.364,,87.71,HHH,-1.49567,0.0758425,0.000795475,0.982976 beta-lactamase_2500_V42F,beta-lactamase_2500_42,TEM-1,beta-lactamase_2500,P62593,0.98298,NO,42,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.564,-3.895,2.331,,0.017,E,B,0.44,-0.51,1.86,,63.99,BHO,-1.042,0.361275,0.00404515,0.98298 beta-lactamase_156_G90A,beta-lactamase_156_90,TEM-1,beta-lactamase_156,P62593,0.982988,NO,90,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-2.091,-2.713,0.622,,0.598,T,A,0.29,0.32,0.319,,77.62,HOB,-1.52633,0.111618,0.00490273,0.982988 beta-lactamase_39_E169H,beta-lactamase_39_169,TEM-1,beta-lactamase_39,P62593,0.982989,NO,169,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.23,-4.45,3.22,,0.337,,A,1.04,1,15.633,15.633,73.08,PAH,-1.16533,0.0495842,0.00400994,0.982989 beta-lactamase_T178S,beta-lactamase_178,TEM-1,beta-lactamase,P62593,0.982998,NO,178,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-0.791,-2.936,2.145,5.06452,0.029,E,B,0.3,-1.07,,,,APP,-0.947667,0.221079,0.000684366,0.982998 beta-lactamase_156_G265N,beta-lactamase_156_265,TEM-1,beta-lactamase_156,P62593,0.983001,NO,265,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.111618,0.00811926,0.983001 beta-lactamase_625_D252Q,beta-lactamase_625_252,TEM-1,beta-lactamase_625,P62593,0.983002,NO,252,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.213352,0.00575769,0.983002 beta-lactamase_625_N98I,beta-lactamase_625_98,TEM-1,beta-lactamase_625,P62593,0.983023,NO,98,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-2.973,-4.064,1.091,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.213352,0.00505389,0.983023 beta-lactamase_39_P165L,beta-lactamase_39_165,TEM-1,beta-lactamase_39,P62593,0.983025,NO,165,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.373,-3.388,2.015,,0.203,T,A,0.52,-0.31,3.907,,73.78,AOA,-1.359,0.0495842,0.00549538,0.983025 beta-lactamase_2500_H156L,beta-lactamase_2500_156,TEM-1,beta-lactamase_2500,P62593,0.983032,NO,156,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-3.156,-3.026,-0.13,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.361275,0.00468596,0.983032 Pab1_A185N,Pab1_185,Pab1,Pab1,P04147,0.983056,NO,185,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.702,-1.835,0.133,,,,,,,1.756,,63.26,AHH,-1.66167,0.175299,0.00144499,0.983056 beta-lactamase_39_T27F,beta-lactamase_39_27,TEM-1,beta-lactamase_39,P62593,0.983058,NO,27,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.905,-2.968,1.063,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.0495842,0.00306559,0.983058 beta-lactamase_625_R273T,beta-lactamase_625_273,TEM-1,beta-lactamase_625,P62593,0.983061,NO,273,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.314,-3.558,1.244,,0.564,H,A,1.2,1.57,1.455,,73.78,ABP,-1.841,0.213352,0.0077952,0.983061 beta-lactamase_39_D207W,beta-lactamase_39_207,TEM-1,beta-lactamase_39,P62593,0.983071,NO,207,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.064,-5.493,3.429,,0.409,H,A,0.75,0.12,14.511,14.511,77.62,HAH,-1.77033,0.0495842,0.00592942,0.983071 beta-lactamase_39_R159Y,beta-lactamase_39_159,TEM-1,beta-lactamase_39,P62593,0.983072,NO,159,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-0.94,-4.035,3.095,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.0495842,0.00108472,0.983072 beta-lactamase_39_M66I,beta-lactamase_39_66,TEM-1,beta-lactamase_39,P62593,0.983074,NO,66,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.362,-2.521,1.159,,0.013,,A,0.55,-0.7,1.319,,73.08,OHH,-1.49567,0.0495842,0.00412876,0.983074 beta-lactamase_E61A,beta-lactamase_61,TEM-1,beta-lactamase,P62593,0.983079,NO,61,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.115,-2.668,0.553,6.29701,0.775,T,a,0.52,1.29,1.975,,77.62,OAA,-1.92567,0.221079,0.00440955,0.983079 beta-lactamase_2500_T198A,beta-lactamase_2500_198,TEM-1,beta-lactamase_2500,P62593,0.98308,NO,198,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.168,-2.502,0.334,,0.489,,B,0.22,-0.13,0.37,,73.78,HPH,-1.98767,0.361275,0.004311,0.98308 beta-lactamase_39_R202M,beta-lactamase_39_202,TEM-1,beta-lactamase_39,P62593,0.983083,NO,202,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.292,-4.499,3.207,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.0495842,0.00321899,0.983083 beta-lactamase_625_M153N,beta-lactamase_625_153,TEM-1,beta-lactamase_625,P62593,0.983085,NO,153,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-3.193,-3.994,0.801,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.213352,0.00509109,0.983085 beta-lactamase_N173H,beta-lactamase_173,TEM-1,beta-lactamase,P62593,0.983094,NO,173,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-2.663,-4.635,1.972,7.02497,1.044,T,l,0.09,1.25,1.88,,77.62,OPA,-1.46633,0.221079,0.0033769,0.983094 beta-lactamase_2500_A211S,beta-lactamase_2500_211,TEM-1,beta-lactamase_2500,P62593,0.983099,NO,211,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.896,-2.788,0.892,,0.369,T,A,0.46,-0.69,2.061,,77.62,AHA,-1.94633,0.361275,0.00648183,0.983099 beta-lactamase_156_L73H,beta-lactamase_156_73,TEM-1,beta-lactamase_156,P62593,0.983104,NO,73,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.507,-4.923,3.416,,,H,A,0.55,-0.64,2.09,,67.83,HHH,-1.487,0.111618,0.00488983,0.983104 beta-lactamase_625_K144M,beta-lactamase_625_144,TEM-1,beta-lactamase_625,P62593,0.983105,NO,144,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-2.388,-4.736,2.348,,0.863,H,A,2.34,1.27,2.313,,77.62,OBA,-1.904,0.213352,0.00481141,0.983105 beta-lactamase_39_S266L,beta-lactamase_39_266,TEM-1,beta-lactamase_39,P62593,0.983107,NO,266,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.0495842,0.0140785,0.983107 beta-lactamase_0_D129Y,beta-lactamase_0_129,TEM-1,beta-lactamase_0,P62593,0.983109,NO,129,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.816,-4.385,3.569,,,,B,0.75,-0.69,2.66,,34.97,PAP,-0.818,0.0500837,0.00109178,0.983109 beta-lactamase_625_S96C,beta-lactamase_625_96,TEM-1,beta-lactamase_625,P62593,0.983109,NO,96,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.27,-5.145,2.875,,0.368,,b,0.27,0.39,5.244,,73.78,HPP,-2.019,0.213352,0.00551835,0.983109 beta-lactamase_156_E56S,beta-lactamase_156_56,TEM-1,beta-lactamase_156,P62593,0.983113,NO,56,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.043,-2.169,0.126,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.111618,0.00238534,0.983113 beta-lactamase_39_L192Q,beta-lactamase_39_192,TEM-1,beta-lactamase_39,P62593,0.983113,NO,192,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.254,-4.246,2.992,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.0495842,0.00558728,0.983113 beta-lactamase_39_L284S,beta-lactamase_39_284,TEM-1,beta-lactamase_39,P62593,0.983115,NO,284,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.0495842,0.0686156,0.983115 beta-lactamase_156_W208N,beta-lactamase_156_208,TEM-1,beta-lactamase_156,P62593,0.98312,NO,208,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-0.818,-4.348,3.53,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.111618,0.00126609,0.98312 beta-lactamase_156_L89R,beta-lactamase_156_89,TEM-1,beta-lactamase_156,P62593,0.983125,NO,89,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.096,-3.963,2.867,,0.168,T,A,0.55,0.63,2.633,,64.34,PHO,-1.75767,0.111618,0.00207068,0.983125 PSD95pdz3_D366I,PSD95pdz3_366,PSD95pdz3,PSD95pdz3,P31016,0.983127,NO,366,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.264,-3.692,2.428,5.55684,,,,,20.2375,,,,HAH,-1.401,0.0758425,0.000481272,0.983127 beta-lactamase_156_E119A,beta-lactamase_156_119,TEM-1,beta-lactamase_156,P62593,0.983129,NO,119,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.412,-2.242,0.83,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.111618,0.00386966,0.983129 beta-lactamase_625_D271V,beta-lactamase_625_271,TEM-1,beta-lactamase_625,P62593,0.983131,NO,271,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.213352,0.00752082,0.983131 beta-lactamase_156_M180K,beta-lactamase_156_180,TEM-1,beta-lactamase_156,P62593,0.983138,NO,180,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-2.795,-3.525,0.73,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.111618,0.00552048,0.983138 beta-lactamase_2500_T264H,beta-lactamase_2500_264,TEM-1,beta-lactamase_2500,P62593,0.983146,NO,264,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.361275,0.0119399,0.983146 beta-lactamase_156_V157E,beta-lactamase_156_157,TEM-1,beta-lactamase_156,P62593,0.983155,NO,157,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.751,-3.68,1.929,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.111618,0.00506849,0.983155 beta-lactamase_156_E119G,beta-lactamase_156_119,TEM-1,beta-lactamase_156,P62593,0.983156,NO,119,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.412,-2.405,0.993,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.111618,0.00386966,0.983156 kka2_1:4_L152Q,kka2_1:4_152,Kka2,kka2_1:4,P00552,0.983164,NO,152,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.521,-2.735,1.214,,0.547,,A,1.59,1.36,2.318,,63.64,OHH,-1.162,0.168804,0.00674868,0.983164 beta-lactamase_39_S283F,beta-lactamase_39_283,TEM-1,beta-lactamase_39,P62593,0.983165,NO,283,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.0495842,0.0429138,0.983165 kka2_1:4_G151R,kka2_1:4_151,Kka2,kka2_1:4,P00552,0.983168,NO,151,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.873,-2.905,2.032,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.168804,0.00339918,0.983168 beta-lactamase_156_R242L,beta-lactamase_156_242,TEM-1,beta-lactamase_156,P62593,0.983174,NO,242,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.111618,0.00452879,0.983174 Pab1_D136Y,Pab1_136,Pab1,Pab1,P04147,0.983179,NO,136,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.602,-4.151,2.549,,,,,,,,,,OAH,-1.42367,0.175299,0.00227029,0.983179 beta-lactamase_156_D36I,beta-lactamase_156_36,TEM-1,beta-lactamase_156,P62593,0.98318,NO,36,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.732,-4.112,1.38,,0.555,H,A,0.75,1.17,14.871,14.871,77.62,AAP,-1.91167,0.111618,0.00476483,0.98318 PSD95pdz3_Q391A,PSD95pdz3_391,PSD95pdz3,PSD95pdz3,P31016,0.983187,NO,391,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-1.699,-2.759,1.06,5.50275,,,,,12.6589,,,,HPH,-1.481,0.0758425,0.000990786,0.983187 beta-lactamase_625_D33H,beta-lactamase_625_33,TEM-1,beta-lactamase_625,P62593,0.983188,NO,33,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.321,-4.654,2.333,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.213352,0.00435556,0.983188 beta-lactamase_625_D252R,beta-lactamase_625_252,TEM-1,beta-lactamase_625,P62593,0.983193,NO,252,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.213352,0.00575769,0.983193 E1_Ubiquitin_G47H,E1_Ubiquitin_47,Uba1,E1_Ubiquitin,P0CG63,0.983201,NO,47,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.999,-4.421,3.422,,0.057,T,l,,-1.21,,,,HOB,-1.195,0.18783,0.00142261,0.983201 E1_Ubiquitin_I44V,E1_Ubiquitin_44,Uba1,E1_Ubiquitin,P0CG63,0.983201,NO,44,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.432,-1.956,0.524,,,E,B,0.27,-1.17,4.57,,78.74,HHH,-1.25633,0.18783,0.00209731,0.983201 beta-lactamase_156_Q97C,beta-lactamase_156_97,TEM-1,beta-lactamase_156,P62593,0.983211,NO,97,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.072,-5.163,3.091,,0.823,G,A,0.64,2.42,4.457,,77.62,PPP,-2.43833,0.111618,0.0045116,0.983211 beta-lactamase_156_P60H,beta-lactamase_156_60,TEM-1,beta-lactamase_156,P62593,0.983223,NO,60,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-2.469,-3.266,0.797,,0.256,T,A,0.52,-0.56,2.947,,77.62,BOA,-1.97633,0.111618,0.00521318,0.983223 beta-lactamase_156_T126I,beta-lactamase_156_126,TEM-1,beta-lactamase_156,P62593,0.983225,NO,126,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.122,-3.78,2.658,,0.05,H,A,0.22,-0.05,1.14,,44.41,HPH,-1.60467,0.111618,0.00244552,0.983225 beta-lactamase_625_T107A,beta-lactamase_625_107,TEM-1,beta-lactamase_625,P62593,0.983225,NO,107,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.117,-2.274,1.157,,,G,A,0.22,-0.06,3.676,,67.83,HPA,-1.265,0.213352,0.00239347,0.983225 beta-lactamase_156_A225T,beta-lactamase_156_225,TEM-1,beta-lactamase_156,P62593,0.983228,NO,225,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.845,-2.966,1.121,,1,T,B,0.46,-0.38,11.722,11.722,74.48,OHO,-1.39967,0.111618,0.00465057,0.983228 beta-lactamase_39_S96W,beta-lactamase_39_96,TEM-1,beta-lactamase_39,P62593,0.983231,NO,96,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.27,-5.497,3.227,,0.368,,b,0.27,0.39,2.516,,73.78,HPP,-2.019,0.0495842,0.00551835,0.983231 beta-lactamase_156_M115A,beta-lactamase_156_115,TEM-1,beta-lactamase_156,P62593,0.98324,NO,115,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.389,-2.535,1.146,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.111618,0.0034337,0.98324 beta-lactamase_39_D252R,beta-lactamase_39_252,TEM-1,beta-lactamase_39,P62593,0.98325,NO,252,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.0495842,0.00575769,0.98325 beta-lactamase_625_L38P,beta-lactamase_625_38,TEM-1,beta-lactamase_625,P62593,0.98325,NO,38,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.343,-2.934,1.591,,0.088,H,A,0.55,0.2,1.986,,64.34,PHO,-1.78033,0.213352,0.00373244,0.98325 beta-lactamase_156_G281Y,beta-lactamase_156_281,TEM-1,beta-lactamase_156,P62593,0.983252,NO,281,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.111618,0.0406482,0.983252 beta-lactamase_625_L111W,beta-lactamase_625_111,TEM-1,beta-lactamase_625,P62593,0.983253,NO,111,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.76,-5.305,3.545,,0.328,T,A,0.55,0.93,2.26,,64.34,BHP,-1.884,0.213352,0.00480671,0.983253 PSD95pdz3_R312G,PSD95pdz3_312,PSD95pdz3,PSD95pdz3,P31016,0.983254,NO,312,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.582,-3.04,1.458,5.76826,,,,,12.2409,,,,OBB,-1.46667,0.0758425,0.00196255,0.983254 beta-lactamase_A276K,beta-lactamase_276,TEM-1,beta-lactamase,P62593,0.983258,NO,276,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.144,-2.603,1.459,5.1387,0.117,H,A,0.52,-0.84,1.283,,44.06,HHA,-1.47,0.221079,0.0191712,0.983258 beta-lactamase_A9I,beta-lactamase_9,TEM-1,beta-lactamase,P62593,0.983258,NO,9,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.147,-2.752,0.605,,,,,,,5.128,,72.73,HHH,-2.04267,0.221079,0.00247263,0.983258 beta-lactamase_D207W,beta-lactamase_207,TEM-1,beta-lactamase,P62593,0.983258,NO,207,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.064,-5.493,3.429,5.40404,0.409,H,A,0.23,0.12,1.975,,77.62,HAH,-1.77033,0.221079,0.00592942,0.983258 beta-lactamase_D269F,beta-lactamase_269,TEM-1,beta-lactamase,P62593,0.983258,NO,269,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.156,-4.42,2.264,5.47645,0.646,H,A,0.23,0.4,21.796,21.796,77.62,HAA,-1.96733,0.221079,0.00950944,0.983258 beta-lactamase_E195R,beta-lactamase_195,TEM-1,beta-lactamase,P62593,0.983258,NO,195,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.186,-3.074,0.888,7.28489,1.016,S,A,1.52,0.85,2.583,,77.62,OAH,-2.02,0.221079,0.00496565,0.983258 beta-lactamase_E270F,beta-lactamase_270,TEM-1,beta-lactamase,P62593,0.983258,NO,270,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.723,-4.387,2.664,5.33196,0.422,H,A,0.52,1.15,1.745,,64.34,AAB,-1.70933,0.221079,0.00767762,0.983258 beta-lactamase_H151E,beta-lactamase_151,TEM-1,beta-lactamase,P62593,0.983258,NO,151,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-2.96,-3.258,0.298,5.47408,0.594,H,A,0.35,0.1,1.843,,77.62,HBP,-2.34767,0.221079,0.00216946,0.983258 beta-lactamase_K109D,beta-lactamase_109,TEM-1,beta-lactamase,P62593,0.983258,NO,109,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.734,-2.919,1.185,6.05842,0.787,G,A,1.82,2.21,21.623,21.623,72.73,ABB,-1.63333,0.221079,0.00462493,0.983258 beta-lactamase_Q204S,beta-lactamase_204,TEM-1,beta-lactamase,P62593,0.983258,NO,204,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-1.382,-3.344,1.962,5.46394,0.204,H,A,0.12,0.09,1.707,,66.08,PPH,-1.49067,0.221079,0.00364106,0.983258 beta-lactamase_Q265M,beta-lactamase_265,TEM-1,beta-lactamase,P62593,0.983258,NO,265,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.58,-4.802,2.222,6.62674,1.116,,A,0.03,1.17,12.514,12.514,69.58,PPH,-1.978,0.221079,0.00811926,0.983258 beta-lactamase_R159H,beta-lactamase_159,TEM-1,beta-lactamase,P62593,0.983258,NO,159,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-0.94,-2.789,1.849,5.64971,0.316,,B,0.68,-0.55,1.172,,64.34,PBH,-1.011,0.221079,0.00108472,0.983258 beta-lactamase_R273L,beta-lactamase_273,TEM-1,beta-lactamase,P62593,0.983258,NO,273,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.314,-3.556,1.242,,0.564,H,A,1.2,1.57,,,73.78,ABP,-1.841,0.221079,0.0077952,0.983258 beta-lactamase_V157S,beta-lactamase_157,TEM-1,beta-lactamase,P62593,0.983258,NO,157,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.751,-2.878,1.127,5.51733,0.308,S,a,0.96,-0.75,1.847,,69.58,BHP,-2.00767,0.221079,0.00506849,0.983258 beta-lactamase_2500_Q204T,beta-lactamase_2500_204,TEM-1,beta-lactamase_2500,P62593,0.983261,NO,204,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-1.382,-3.549,2.167,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.361275,0.00364106,0.983261 PSD95pdz3_G322I,PSD95pdz3_322,PSD95pdz3,PSD95pdz3,P31016,0.983268,NO,322,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.008,-3.917,2.909,5.24791,,,,,16.3275,,,,POH,-1.24867,0.0758425,0.00105821,0.983268 beta-lactamase_156_S241H,beta-lactamase_156_241,TEM-1,beta-lactamase_156,P62593,0.983288,NO,241,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.111618,0.00452736,0.983288 beta-lactamase_625_D113W,beta-lactamase_625_113,TEM-1,beta-lactamase_625,P62593,0.983291,NO,113,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.829,-5.545,3.716,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.213352,0.00474112,0.983291 beta-lactamase_625_P25R,beta-lactamase_625_25,TEM-1,beta-lactamase_625,P62593,0.983301,NO,25,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.526,-3.8,2.274,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.213352,0.00347571,0.983301 Pab1_D160E,Pab1_160,Pab1,Pab1,P04147,0.983301,NO,160,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.985,-2.582,1.597,,0.396,B,B,,1.12,,,,PAA,-1.30133,0.175299,0.000311977,0.983301 beta-lactamase_156_Q276T,beta-lactamase_156_276,TEM-1,beta-lactamase_156,P62593,0.983305,NO,276,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.111618,0.0191712,0.983305 beta-lactamase_156_A215I,beta-lactamase_156_215,TEM-1,beta-lactamase_156,P62593,0.983308,NO,215,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.503,-3.916,2.413,,,,a,0.46,-0.93,3.583,,74.48,HHO,-1.42633,0.111618,0.00544007,0.983308 beta-lactamase_39_G90R,beta-lactamase_39_90,TEM-1,beta-lactamase_39,P62593,0.983311,NO,90,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-2.091,-3.098,1.007,,0.598,T,A,0.29,0.32,30.794,30.794,77.62,HOB,-1.52633,0.0495842,0.00490273,0.983311 beta-lactamase_625_A123V,beta-lactamase_625_123,TEM-1,beta-lactamase_625,P62593,0.983314,NO,123,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.834,-2.392,1.558,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.213352,0.0010157,0.983314 beta-lactamase_39_M153Q,beta-lactamase_39_153,TEM-1,beta-lactamase_39,P62593,0.983326,NO,153,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-3.193,-4.202,1.009,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.0495842,0.00509109,0.983326 beta-lactamase_2500_N98T,beta-lactamase_2500_98,TEM-1,beta-lactamase_2500,P62593,0.983328,NO,98,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-2.973,-2.907,-0.066,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.361275,0.00505389,0.983328 beta-lactamase_39_E169Y,beta-lactamase_39_169,TEM-1,beta-lactamase_39,P62593,0.983335,NO,169,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.23,-4.247,3.017,,0.337,,A,1.04,1,15.633,15.633,73.08,PAH,-1.16533,0.0495842,0.00400994,0.983335 beta-lactamase_156_A200I,beta-lactamase_156_200,TEM-1,beta-lactamase_156,P62593,0.983345,NO,200,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.878,-3.937,2.059,,0.757,H,A,0.46,-0.19,16.368,16.368,77.62,HHP,-2.001,0.111618,0.0060056,0.983345 beta-lactamase_156_H151V,beta-lactamase_156_151,TEM-1,beta-lactamase_156,P62593,0.983359,NO,151,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-2.96,-3.785,0.825,,0.594,H,A,0.17,0.1,1.401,,77.62,HBP,-2.34767,0.111618,0.00216946,0.983359 beta-lactamase_2500_L111F,beta-lactamase_2500_111,TEM-1,beta-lactamase_2500,P62593,0.983363,NO,111,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.76,-2.976,1.216,,0.328,T,A,0.55,0.93,1.966,,64.34,BHP,-1.884,0.361275,0.00480671,0.983363 beta-lactamase_156_G141D,beta-lactamase_156_141,TEM-1,beta-lactamase_156,P62593,0.983365,NO,141,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.828,-2.284,1.456,,0.575,T,l,0.29,-0.28,0.198,,64.69,HOO,-1.08933,0.111618,0.0012419,0.983365 beta-lactamase_625_Q204E,beta-lactamase_625_204,TEM-1,beta-lactamase_625,P62593,0.983374,NO,204,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-1.382,-3.106,1.724,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.213352,0.00364106,0.983374 PSD95pdz3_Q384S,PSD95pdz3_384,PSD95pdz3,PSD95pdz3,P31016,0.983376,NO,384,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-1.699,-2.842,1.143,5.49339,,,,,23.54,,,,OPP,-1.41333,0.0758425,0.000216736,0.983376 beta-lactamase_2500_G253R,beta-lactamase_2500_253,TEM-1,beta-lactamase_2500,P62593,0.983382,NO,253,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.361275,0.00786358,0.983382 beta-lactamase_E56K,beta-lactamase_56,TEM-1,beta-lactamase,P62593,0.983384,NO,56,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.043,-3.327,1.284,5.65281,0.198,E,B,0.52,0.31,2.022,,72.73,HAP,-1.94033,0.221079,0.00238534,0.983384 beta-lactamase_156_Q204W,beta-lactamase_156_204,TEM-1,beta-lactamase_156,P62593,0.98339,NO,204,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-1.382,-5.303,3.921,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.111618,0.00364106,0.98339 beta-lactamase_39_V117T,beta-lactamase_39_117,TEM-1,beta-lactamase_39,P62593,0.983392,NO,117,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.53,-3.486,1.956,,,H,A,0.44,-0.34,1.182,,65.03,PHB,-1.741,0.0495842,0.00467906,0.983392 beta-lactamase_W163C,beta-lactamase_163,TEM-1,beta-lactamase,P62593,0.983392,NO,163,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-1.843,-5.117,3.274,6.2765,0.467,,B,1.22,-0.5,3.642,,63.99,BHA,-1.269,0.221079,0.00418955,0.983392 beta-lactamase_625_N168C,beta-lactamase_625_168,TEM-1,beta-lactamase_625,P62593,0.983396,NO,168,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-1.029,-4.99,3.961,,0.113,G,A,0.61,-0.4,1.014,,44.41,HPA,-1.13233,0.213352,0.00288667,0.983396 beta-lactamase_625_F149V,beta-lactamase_625_149,TEM-1,beta-lactamase_625,P62593,0.9834,NO,149,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.299,-3.45,2.151,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.213352,0.00418462,0.9834 PSD95pdz3_A378Y,PSD95pdz3_378,PSD95pdz3,PSD95pdz3,P31016,0.9834,NO,378,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.307,-3.844,2.537,4.86582,,,,,14.576,,,,HHH,-1.509,0.0758425,0.000313169,0.9834 beta-lactamase_625_D252A,beta-lactamase_625_252,TEM-1,beta-lactamase_625,P62593,0.983403,NO,252,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.213352,0.00575769,0.983403 PSD95pdz3_A343I,PSD95pdz3_343,PSD95pdz3,PSD95pdz3,P31016,0.983403,NO,343,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.307,-3.242,1.935,5.585,,,,,14.728,,,,HHO,-1.22067,0.0758425,0.000798084,0.983403 beta-lactamase_156_R81Q,beta-lactamase_156_81,TEM-1,beta-lactamase_156,P62593,0.983406,NO,81,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.466,-2.446,0.98,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.111618,0.00499763,0.983406 beta-lactamase_156_F70N,beta-lactamase_156_70,TEM-1,beta-lactamase_156,P62593,0.983409,NO,70,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.169,-4.034,2.865,,,H,A,0.58,-1.34,1.918,,63.99,PHB,-0.980667,0.111618,0.00193499,0.983409 kka2_1:8_A129I,kka2_1:8_129,Kka2,kka2_1:8,P00552,0.983414,NO,129,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.656,-3.236,1.58,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.100394,0.00726862,0.983414 kka2_1:8_A129I,kka2_1:8_129,Kka2,kka2_1:8,P00552,0.983414,NO,129,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.656,-3.236,1.58,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.100394,0.00726862,0.983414 Pab1_E181L,Pab1_181,Pab1,Pab1,P04147,0.983417,NO,181,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.767,-3.358,1.591,,,,,,,1.395,,73.83,BAH,-1.575,0.175299,0.00107557,0.983417 beta-lactamase_625_G265N,beta-lactamase_625_265,TEM-1,beta-lactamase_625,P62593,0.983418,NO,265,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.213352,0.00811926,0.983418 beta-lactamase_156_A268P,beta-lactamase_156_268,TEM-1,beta-lactamase_156,P62593,0.983419,NO,268,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.111618,0.0102525,0.983419 beta-lactamase_39_Y103V,beta-lactamase_39_103,TEM-1,beta-lactamase_39,P62593,0.98342,NO,103,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-1.33,-3.602,2.272,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.0495842,0.00443048,0.98342 beta-lactamase_156_M153Q,beta-lactamase_156_153,TEM-1,beta-lactamase_156,P62593,0.983431,NO,153,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-3.193,-4.202,1.009,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.111618,0.00509109,0.983431 beta-lactamase_39_M184C,beta-lactamase_39_184,TEM-1,beta-lactamase_39,P62593,0.983433,NO,184,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.593,-4.787,3.194,,,H,A,0.55,-0.87,2.893,,62.94,HHH,-1.41,0.0495842,0.00356019,0.983433 beta-lactamase_625_E62Q,beta-lactamase_625_62,TEM-1,beta-lactamase_625,P62593,0.983434,NO,62,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.193,-2.5,1.307,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.213352,0.00264802,0.983434 beta-lactamase_39_S256L,beta-lactamase_39_256,TEM-1,beta-lactamase_39,P62593,0.98344,NO,256,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.0495842,0.00710634,0.98344 beta-lactamase_E175F,beta-lactamase_175,TEM-1,beta-lactamase,P62593,0.983442,NO,175,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.336,-4.36,2.024,6.0311,0.551,,A,0.75,1.05,5.316,,77.62,AAB,-1.31233,0.221079,0.00482205,0.983442 Pab1_T159G,Pab1_159,Pab1,Pab1,P04147,0.983444,NO,159,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.445,-3.188,1.743,,,,,,,2.531,,79.03,HPA,-1.19467,0.175299,0.00133849,0.983444 beta-lactamase_39_L191G,beta-lactamase_39_191,TEM-1,beta-lactamase_39,P62593,0.983445,NO,191,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.087,-3.655,2.568,,,H,A,0.55,0.09,1.372,,63.29,BHH,-1.445,0.0495842,0.00263549,0.983445 beta-lactamase_625_H287A,beta-lactamase_625_287,TEM-1,beta-lactamase_625,P62593,0.983447,NO,287,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,,,,,,,,,,,,,BBH,-1.111,0.213352,,0.983447 beta-lactamase_156_N168M,beta-lactamase_156_168,TEM-1,beta-lactamase_156,P62593,0.98345,NO,168,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-1.029,-4.683,3.654,,0.113,G,A,0.61,-0.4,1.014,,44.41,HPA,-1.13233,0.111618,0.00288667,0.98345 beta-lactamase_625_W163A,beta-lactamase_625_163,TEM-1,beta-lactamase_625,P62593,0.983456,NO,163,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-1.843,-3.41,1.567,,0.467,,B,0.47,-0.5,5.019,,63.99,BHA,-1.269,0.213352,0.00418955,0.983456 beta-lactamase_625_P172Q,beta-lactamase_625_172,TEM-1,beta-lactamase_625,P62593,0.983467,NO,172,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.998,-3.965,2.967,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.213352,0.00312594,0.983467 beta-lactamase_39_M153T,beta-lactamase_39_153,TEM-1,beta-lactamase_39,P62593,0.983476,NO,153,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-3.193,-2.237,-0.956,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.0495842,0.00509109,0.983476 beta-lactamase_156_G114C,beta-lactamase_156_114,TEM-1,beta-lactamase_156,P62593,0.983477,NO,114,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.094,-5.014,3.92,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.111618,0.00224919,0.983477 beta-lactamase_625_I171Q,beta-lactamase_625_171,TEM-1,beta-lactamase_625,P62593,0.983478,NO,171,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-2.431,-3.168,0.737,,0.361,,B,0.48,0.53,3.869,,77.62,HHO,-1.55533,0.213352,0.00623355,0.983478 beta-lactamase_156_R189D,beta-lactamase_156_189,TEM-1,beta-lactamase_156,P62593,0.98348,NO,189,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.844,-2.871,1.027,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.111618,0.0050699,0.98348 beta-lactamase_39_Y262S,beta-lactamase_39_262,TEM-1,beta-lactamase_39,P62593,0.983485,NO,262,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.0495842,0.00853516,0.983485 beta-lactamase_625_T198D,beta-lactamase_625_198,TEM-1,beta-lactamase_625,P62593,0.983485,NO,198,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.168,-3.544,1.376,,0.489,,B,0.22,-0.13,0.37,,73.78,HPH,-1.98767,0.213352,0.004311,0.983485 beta-lactamase_39_A133T,beta-lactamase_39_133,TEM-1,beta-lactamase_39,P62593,0.983486,NO,133,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.186,-2.382,1.196,,,H,A,0.46,-0.86,0.373,,67.83,HHP,-0.988333,0.0495842,0.00468022,0.983486 beta-lactamase_625_Y44L,beta-lactamase_625_44,TEM-1,beta-lactamase_625,P62593,0.983486,NO,44,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-2.547,-2.196,-0.351,,,E,B,0.21,-0.45,2.371,,73.78,OHH,-1.86267,0.213352,0.00426364,0.983486 beta-lactamase_39_E169G,beta-lactamase_39_169,TEM-1,beta-lactamase_39,P62593,0.983487,NO,169,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.23,-3.348,2.118,,0.337,,A,1.04,1,15.633,15.633,73.08,PAH,-1.16533,0.0495842,0.00400994,0.983487 beta-lactamase_39_S57Q,beta-lactamase_39_57,TEM-1,beta-lactamase_39,P62593,0.983491,NO,57,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.918,-3.995,2.077,,0.352,E,B,0.27,-0.18,2.3,,72.73,APH,-2.29167,0.0495842,0.00492804,0.983491 beta-lactamase_39_Q37E,beta-lactamase_39_37,TEM-1,beta-lactamase_39,P62593,0.983493,NO,37,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.134,-2.427,0.293,,0.613,H,A,0.64,1.98,22.282,22.282,73.08,APH,-2.06967,0.0495842,0.00425833,0.983493 beta-lactamase_625_F228A,beta-lactamase_625_228,TEM-1,beta-lactamase_625,P62593,0.9835,NO,228,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-2.342,-2.562,0.22,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.213352,0.0046669,0.9835 beta-lactamase_156_P105A,beta-lactamase_156_105,TEM-1,beta-lactamase_156,P62593,0.983503,NO,105,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.813,-3.041,2.228,,0.226,T,A,0.52,0.8,1.154,,63.29,POH,-1.01533,0.111618,0.0011981,0.983503 beta-lactamase_2500_K144D,beta-lactamase_2500_144,TEM-1,beta-lactamase_2500,P62593,0.983506,NO,144,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-2.388,-3.584,1.196,,0.863,H,A,2.34,1.27,0.515,,77.62,OBA,-1.904,0.361275,0.00481141,0.983506 beta-lactamase_156_E102A,beta-lactamase_156_102,TEM-1,beta-lactamase_156,P62593,0.983507,NO,102,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.118,-2.327,0.209,,0.722,S,B,1.04,1.82,15.721,15.721,73.08,HAH,-1.581,0.111618,0.00486633,0.983507 Pab1_T159I,Pab1_159,Pab1,Pab1,P04147,0.98351,NO,159,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.445,-3.415,1.97,,,,,,,2.531,,79.03,HPA,-1.19467,0.175299,0.00133849,0.98351 beta-lactamase_156_L199G,beta-lactamase_156_199,TEM-1,beta-lactamase_156,P62593,0.983511,NO,199,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-2.942,-2.663,-0.279,,0.832,H,A,0.55,0.42,1.552,,77.62,PHH,-2.32933,0.111618,0.0048649,0.983511 beta-lactamase_E277D,beta-lactamase_277,TEM-1,beta-lactamase,P62593,0.983512,NO,277,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.869,-1.924,0.055,5.51786,0.545,H,A,0.52,-0.01,2.022,,77.62,HAH,-1.45367,0.221079,0.0169305,0.983512 beta-lactamase_625_D99T,beta-lactamase_625_99,TEM-1,beta-lactamase_625,P62593,0.983515,NO,99,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.191,-3.531,2.34,,0.402,G,A,0.75,0.36,1.318,,64.69,PAH,-1.794,0.213352,0.00305446,0.983515 beta-lactamase_39_L111Q,beta-lactamase_39_111,TEM-1,beta-lactamase_39,P62593,0.983518,NO,111,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.76,-3.108,1.348,,0.328,T,A,0.55,0.93,4.334,,64.34,BHP,-1.884,0.0495842,0.00480671,0.983518 beta-lactamase_2500_H94S,beta-lactamase_2500_94,TEM-1,beta-lactamase_2500,P62593,0.983525,NO,94,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-2.5,-3.499,0.999,,0.776,,B,0.17,1.24,1.176,,77.62,HBH,-1.872,0.361275,0.00389226,0.983525 beta-lactamase_2500_A278S,beta-lactamase_2500_278,TEM-1,beta-lactamase_2500,P62593,0.983529,NO,278,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.361275,0.0310297,0.983529 beta-lactamase_2500_T139V,beta-lactamase_2500_139,TEM-1,beta-lactamase_2500,P62593,0.983542,NO,139,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.901,-3.468,1.567,,0.216,H,A,0.22,0.39,2.256,,77.62,PPH,-2.04667,0.361275,0.00441837,0.983542 kka2_1:8_P109S,kka2_1:8_109,Kka2,kka2_1:8,P00552,0.983544,NO,109,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.412,-2.854,1.442,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.100394,0.0070929,0.983544 kka2_1:8_P109S,kka2_1:8_109,Kka2,kka2_1:8,P00552,0.983544,NO,109,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.412,-2.854,1.442,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.100394,0.0070929,0.983544 beta-lactamase_39_N50C,beta-lactamase_39_50,TEM-1,beta-lactamase_39,P62593,0.983547,NO,50,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-2.979,-5.044,2.065,,0.912,T,A,0.61,1.24,10.736,,77.62,HPP,-2.134,0.0495842,0.0047211,0.983547 beta-lactamase_G85H,beta-lactamase_85,TEM-1,beta-lactamase,P62593,0.983549,NO,85,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.011,-4.646,3.635,5.58951,0.805,T,l,0.23,1.7,1.468,,63.64,HOP,-1.68733,0.221079,0.00252173,0.983549 beta-lactamase_156_M127C,beta-lactamase_156_127,TEM-1,beta-lactamase_156,P62593,0.983559,NO,127,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-2.251,-5.009,2.758,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.111618,0.00437927,0.983559 PSD95pdz3_A370T,PSD95pdz3_370,PSD95pdz3,PSD95pdz3,P31016,0.983569,NO,370,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.307,-2.878,1.571,5.22304,,,,,17.284,,,,PHP,-1.57967,0.0758425,0.000429106,0.983569 beta-lactamase_156_S266W,beta-lactamase_156_266,TEM-1,beta-lactamase_156,P62593,0.983577,NO,266,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.111618,0.0140785,0.983577 beta-lactamase_156_G240S,beta-lactamase_156_240,TEM-1,beta-lactamase_156,P62593,0.983578,NO,240,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.537,-2.475,0.938,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.111618,0.00591201,0.983578 beta-lactamase_39_L146H,beta-lactamase_39_146,TEM-1,beta-lactamase_39,P62593,0.98358,NO,146,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.462,-4.92,3.458,,0.007,H,A,0.55,-0.56,1.953,,64.69,AHP,-1.656,0.0495842,0.00474542,0.98358 beta-lactamase_2500_L111T,beta-lactamase_2500_111,TEM-1,beta-lactamase_2500,P62593,0.983582,NO,111,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.76,-2.765,1.005,,0.328,T,A,0.55,0.93,1.966,,64.34,BHP,-1.884,0.361275,0.00480671,0.983582 gb1_K236S,gb1_236,gb1,gb1,P06654,0.983582,NO,236,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-2.119,-2.918,0.799,,,,,,,1.083,,45.54,OBP,-1.758,0.177985,0.00255408,0.983582 gb1_Q258S,gb1_258,gb1,gb1,P06654,0.983582,NO,258,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.095,-2.951,0.856,,,,,,,0.86,,37.28,BPH,-1.88333,0.177985,0.00437595,0.983582 beta-lactamase_0_I45M,beta-lactamase_0_45,TEM-1,beta-lactamase_0,P62593,0.983584,NO,45,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-2.421,-3.375,0.954,,,E,B,0.48,-0.3,1.375,,77.62,HHA,-2.30267,0.0500837,0.00452842,0.983584 beta-lactamase_39_E210F,beta-lactamase_39_210,TEM-1,beta-lactamase_39,P62593,0.983584,NO,210,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.319,-4.128,1.809,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.0495842,0.00663582,0.983584 beta-lactamase_2500_E119Q,beta-lactamase_2500_119,TEM-1,beta-lactamase_2500,P62593,0.983587,NO,119,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.412,-2.449,1.037,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.361275,0.00386966,0.983587 beta-lactamase_156_E119R,beta-lactamase_156_119,TEM-1,beta-lactamase_156,P62593,0.983588,NO,119,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.412,-3.743,2.331,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.111618,0.00386966,0.983588 beta-lactamase_2500_D33R,beta-lactamase_2500_33,TEM-1,beta-lactamase_2500,P62593,0.98359,NO,33,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.321,-2.617,0.296,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.361275,0.00435556,0.98359 beta-lactamase_156_Q203L,beta-lactamase_156_203,TEM-1,beta-lactamase_156,P62593,0.983592,NO,203,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.168,-2.697,0.529,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.111618,0.00631514,0.983592 kka2_1:8_A176E,kka2_1:8_176,Kka2,kka2_1:8,P00552,0.983596,NO,176,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.621,-2.534,0.913,,0.806,H,A,0.46,-0.03,18.904,18.904,65.53,BHB,-2.26667,0.100394,0.0083587,0.983596 kka2_1:8_A176E,kka2_1:8_176,Kka2,kka2_1:8,P00552,0.983596,NO,176,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.621,-2.534,0.913,,0.806,H,A,0.46,-0.03,18.904,18.904,65.53,BHB,-2.26667,0.100394,0.0083587,0.983596 beta-lactamase_A183H,beta-lactamase_183,TEM-1,beta-lactamase,P62593,0.983599,NO,183,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.231,-4.624,3.393,4.84712,0.155,H,A,0.55,-0.91,12.189,,77.62,HHH,-1.53367,0.221079,0.00296631,0.983599 beta-lactamase_I54T,beta-lactamase_54,TEM-1,beta-lactamase,P62593,0.983599,NO,54,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-2.838,-2.043,-0.795,5.40541,0.669,E,B,0.77,-0.14,3.946,,73.78,BHH,-2.337,0.221079,0.00403589,0.983599 beta-lactamase_P12N,beta-lactamase_12,TEM-1,beta-lactamase,P62593,0.983599,NO,12,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-2.016,-3.829,1.813,,,,,,,2.88,,72.73,HOH,-2.05167,0.221079,0.00241653,0.983599 beta-lactamase_0_L205G,beta-lactamase_0_205,TEM-1,beta-lactamase_0,P62593,0.983613,NO,205,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.922,-3.783,2.861,,,H,A,0.55,-0.46,1.065,,42.31,PHH,-1.57767,0.0500837,0.00255802,0.983613 beta-lactamase_625_K254G,beta-lactamase_625_254,TEM-1,beta-lactamase_625,P62593,0.983621,NO,254,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.213352,0.00369,0.983621 beta-lactamase_G39D,beta-lactamase_39,TEM-1,beta-lactamase,P62593,0.983631,NO,39,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.864,-2.194,0.33,5.35574,0.701,T,L,0.23,0.47,29.926,29.926,77.62,HOH,-1.53633,0.221079,0.00487611,0.983631 kka2_1:2_A71T,kka2_1:2_71,Kka2,kka2_1:2,P00552,0.983634,NO,71,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.824,-2.666,0.842,,0.553,H,A,0.46,0.08,9.788,,64.39,HHP,-1.74033,0.295029,0.00727707,0.983634 beta-lactamase_I125V,beta-lactamase_125,TEM-1,beta-lactamase,P62593,0.983638,NO,125,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.441,-2.101,0.66,5.23481,,H,A,2.82,-0.7,2.301,,63.29,HHP,-1.248,0.221079,0.00383964,0.983638 beta-lactamase_2500_L100V,beta-lactamase_2500_100,TEM-1,beta-lactamase_2500,P62593,0.983641,NO,100,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.218,-2.049,0.831,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.361275,0.00413885,0.983641 beta-lactamase_2500_R239C,beta-lactamase_2500_239,TEM-1,beta-lactamase_2500,P62593,0.983641,NO,239,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.361275,0.00213852,0.983641 beta-lactamase_625_A185G,beta-lactamase_625_185,TEM-1,beta-lactamase_625,P62593,0.983647,NO,185,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.406,-3.37,1.964,,,H,A,0.46,-1.02,0.365,,65.03,HHP,-1.84033,0.213352,0.00467449,0.983647 beta-lactamase_625_G85C,beta-lactamase_625_85,TEM-1,beta-lactamase_625,P62593,0.983653,NO,85,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.011,-5.172,4.161,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.213352,0.00252173,0.983653 beta-lactamase_39_T116D,beta-lactamase_39_116,TEM-1,beta-lactamase_39,P62593,0.983658,NO,116,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.28,-3.524,2.244,,0.115,E,B,0.22,-0.12,1.133,,67.48,HPH,-1.39967,0.0495842,0.00336175,0.983658 beta-lactamase_39_H94T,beta-lactamase_39_94,TEM-1,beta-lactamase_39,P62593,0.983663,NO,94,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-2.5,-2.6,0.1,,0.776,,B,0.17,1.24,11.583,11.583,77.62,HBH,-1.872,0.0495842,0.00389226,0.983663 beta-lactamase_156_G265C,beta-lactamase_156_265,TEM-1,beta-lactamase_156,P62593,0.983669,NO,265,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.111618,0.00811926,0.983669 beta-lactamase_E87M,beta-lactamase_87,TEM-1,beta-lactamase,P62593,0.983669,NO,87,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.421,-4.574,3.153,5.41929,0.048,,B,0.52,0.92,1.754,,64.69,PAP,-1.969,0.221079,0.00337888,0.983669 beta-lactamase_156_Q203R,beta-lactamase_156_203,TEM-1,beta-lactamase_156,P62593,0.983672,NO,203,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.168,-2.451,0.283,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.111618,0.00631514,0.983672 beta-lactamase_625_G85D,beta-lactamase_625_85,TEM-1,beta-lactamase_625,P62593,0.983673,NO,85,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.011,-2.383,1.372,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.213352,0.00252173,0.983673 beta-lactamase_2500_D271G,beta-lactamase_2500_271,TEM-1,beta-lactamase_2500,P62593,0.983675,NO,271,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.361275,0.00752082,0.983675 beta-lactamase_156_D33C,beta-lactamase_156_33,TEM-1,beta-lactamase_156,P62593,0.98368,NO,33,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.321,-5.054,2.733,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.111618,0.00435556,0.98368 beta-lactamase_39_V42N,beta-lactamase_39_42,TEM-1,beta-lactamase_39,P62593,0.98368,NO,42,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.564,-4.165,2.601,,0.017,E,B,0.44,-0.51,1.86,,63.99,BHO,-1.042,0.0495842,0.00404515,0.98368 beta-lactamase_39_G114W,beta-lactamase_39_114,TEM-1,beta-lactamase_39,P62593,0.983686,NO,114,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.094,-5.288,4.194,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.0495842,0.00224919,0.983686 beta-lactamase_2500_D33S,beta-lactamase_2500_33,TEM-1,beta-lactamase_2500,P62593,0.983693,NO,33,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.321,-2.627,0.306,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.361275,0.00435556,0.983693 beta-lactamase_156_L136V,beta-lactamase_156_136,TEM-1,beta-lactamase_156,P62593,0.983697,NO,136,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.232,-1.932,0.7,,,H,A,0.55,-0.34,1.04,,48.95,HHH,-1.088,0.111618,0.00442304,0.983697 beta-lactamase_39_P65R,beta-lactamase_39_65,TEM-1,beta-lactamase_39,P62593,0.9837,NO,65,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.894,-3.951,3.057,,0.098,E,B,0.52,-0.62,0.623,,40.56,HOH,-1.03233,0.0495842,0.00152776,0.9837 beta-lactamase_39_A282Y,beta-lactamase_39_282,TEM-1,beta-lactamase_39,P62593,0.983702,NO,282,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.0495842,0.0449821,0.983702 beta-lactamase_2500_A268Y,beta-lactamase_2500_268,TEM-1,beta-lactamase_2500,P62593,0.983705,NO,268,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.361275,0.0102525,0.983705 beta-lactamase_2500_Q276E,beta-lactamase_2500_276,TEM-1,beta-lactamase_2500,P62593,0.983707,NO,276,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.361275,0.0191712,0.983707 beta-lactamase_156_K254I,beta-lactamase_156_254,TEM-1,beta-lactamase_156,P62593,0.983709,NO,254,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.111618,0.00369,0.983709 beta-lactamase_156_D252S,beta-lactamase_156_252,TEM-1,beta-lactamase_156,P62593,0.983722,NO,252,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.111618,0.00575769,0.983722 beta-lactamase_625_W227Y,beta-lactamase_625_227,TEM-1,beta-lactamase_625,P62593,0.983729,NO,227,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-0.982,-3.356,2.374,,0.272,,B,0.47,-0.29,2.533,,74.48,OHH,-1.595,0.213352,0.00226019,0.983729 PSD95pdz3_K380N,PSD95pdz3_380,PSD95pdz3,PSD95pdz3,P31016,0.983731,NO,380,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.416,-3.13,1.714,5.87979,,,,,19.6722,,,,HBP,-1.391,0.0758425,0.000281399,0.983731 beta-lactamase_625_D113C,beta-lactamase_625_113,TEM-1,beta-lactamase_625,P62593,0.983735,NO,113,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.829,-5.156,3.327,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.213352,0.00474112,0.983735 beta-lactamase_39_V117I,beta-lactamase_39_117,TEM-1,beta-lactamase_39,P62593,0.98374,NO,117,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.53,-1.923,0.393,,,H,A,0.44,-0.34,1.182,,65.03,PHB,-1.741,0.0495842,0.00467906,0.98374 beta-lactamase_625_G85V,beta-lactamase_625_85,TEM-1,beta-lactamase_625,P62593,0.983745,NO,85,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.011,-3.796,2.785,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.213352,0.00252173,0.983745 beta-lactamase_39_G142R,beta-lactamase_39_142,TEM-1,beta-lactamase_39,P62593,0.983748,NO,142,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.707,-3.93,3.223,,0.034,,p,0.29,-0.64,1.947,,64.69,OOO,-0.834,0.0495842,0.00060149,0.983748 beta-lactamase_39_K30V,beta-lactamase_39_30,TEM-1,beta-lactamase_39,P62593,0.983748,NO,30,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-2.307,-2.807,0.5,,0.142,H,A,2.34,-0.65,6.717,,93.01,HBH,-2.32833,0.0495842,0.00448593,0.983748 beta-lactamase_39_K254F,beta-lactamase_39_254,TEM-1,beta-lactamase_39,P62593,0.983753,NO,254,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.0495842,0.00369,0.983753 gb1_T279R,gb1_279,gb1,gb1,P06654,0.98376,NO,279,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.32,-3.657,2.337,,,,,,,0.529,,35.71,HPH,-1.50067,0.177985,0.00421454,0.98376 beta-lactamase_2500_A183H,beta-lactamase_2500_183,TEM-1,beta-lactamase_2500,P62593,0.983766,NO,183,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.231,-4.624,3.393,,0.155,H,A,0.46,-0.91,12.189,,77.62,HHH,-1.53367,0.361275,0.00296631,0.983766 beta-lactamase_G154G,beta-lactamase_154,TEM-1,beta-lactamase,P62593,0.983775,NO,154,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.823,-0.823,,5.40944,0.54,T,l,0.77,-0.56,2.283,,64.69,HOA,-1.635,0.221079,0.00180205,0.983775 beta-lactamase_0_F70A,beta-lactamase_0_70,TEM-1,beta-lactamase_0,P62593,0.98378,NO,70,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.169,-3.227,2.058,,,H,A,0.58,-1.34,2.153,,63.99,PHB,-0.980667,0.0500837,0.00193499,0.98378 beta-lactamase_39_T193Q,beta-lactamase_39_193,TEM-1,beta-lactamase_39,P62593,0.98378,NO,193,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.914,-4.169,2.255,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.0495842,0.00482669,0.98378 beta-lactamase_625_A225T,beta-lactamase_625_225,TEM-1,beta-lactamase_625,P62593,0.983793,NO,225,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.845,-2.966,1.121,,1,T,B,0.46,-0.38,9.874,9.874,74.48,OHO,-1.39967,0.213352,0.00465057,0.983793 beta-lactamase_156_D252A,beta-lactamase_156_252,TEM-1,beta-lactamase_156,P62593,0.983804,NO,252,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.111618,0.00575769,0.983804 beta-lactamase_39_S241M,beta-lactamase_39_241,TEM-1,beta-lactamase_39,P62593,0.98381,NO,241,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.0495842,0.00452736,0.98381 beta-lactamase_2500_N173M,beta-lactamase_2500_173,TEM-1,beta-lactamase_2500,P62593,0.983812,NO,173,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-2.663,-4.901,2.238,,1.044,T,l,0.61,1.25,1.88,,77.62,OPA,-1.46633,0.361275,0.0033769,0.983812 beta-lactamase_2500_N98A,beta-lactamase_2500_98,TEM-1,beta-lactamase_2500,P62593,0.983814,NO,98,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-2.973,-2.132,-0.841,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.361275,0.00505389,0.983814 beta-lactamase_0_L137M,beta-lactamase_0_137,TEM-1,beta-lactamase_0,P62593,0.983816,NO,137,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.03,-2.58,1.55,,,H,A,0.55,-0.38,0.328,,42.31,HHP,-1.58933,0.0500837,0.00278599,0.983816 beta-lactamase_156_E56F,beta-lactamase_156_56,TEM-1,beta-lactamase_156,P62593,0.983816,NO,56,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.043,-4.191,2.148,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.111618,0.00238534,0.983816 beta-lactamase_156_P105N,beta-lactamase_156_105,TEM-1,beta-lactamase_156,P62593,0.983819,NO,105,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.813,-3.82,3.007,,0.226,T,A,0.52,0.8,1.154,,63.29,POH,-1.01533,0.111618,0.0011981,0.983819 beta-lactamase_156_E169V,beta-lactamase_156_169,TEM-1,beta-lactamase_156,P62593,0.98382,NO,169,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.23,-3.538,2.308,,0.337,,A,1.04,1,3.516,,73.08,PAH,-1.16533,0.111618,0.00400994,0.98382 Pab1_A178Y,Pab1_178,Pab1,Pab1,P04147,0.983821,NO,178,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.579,-4.132,2.553,,0.019,H,A,0.64,0.64,2.7,,81.63,OHH,-1.61067,0.175299,0.00160192,0.983821 beta-lactamase_39_I285N,beta-lactamase_39_285,TEM-1,beta-lactamase_39,P62593,0.983823,NO,285,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.0495842,0.101555,0.983823 beta-lactamase_Y44F,beta-lactamase_44,TEM-1,beta-lactamase,P62593,0.983824,NO,44,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-2.547,-2.714,0.167,5.6273,,E,B,2.55,-0.45,2.683,,73.78,OHH,-1.86267,0.221079,0.00426364,0.983824 beta-lactamase_156_Y262F,beta-lactamase_156_262,TEM-1,beta-lactamase_156,P62593,0.983825,NO,262,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.111618,0.00853516,0.983825 beta-lactamase_39_Q86E,beta-lactamase_39_86,TEM-1,beta-lactamase_39,P62593,0.983827,NO,86,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.4,-2.379,-0.021,,0.696,S,A,0.64,2.38,27.704,27.704,77.62,OPA,-1.61067,0.0495842,0.00450027,0.983827 beta-lactamase_156_N152Y,beta-lactamase_156_152,TEM-1,beta-lactamase_156,P62593,0.983834,NO,152,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-2.757,-4.312,1.555,,0.863,H,A,0.61,0.92,4.038,,77.62,BPH,-2.97,0.111618,0.00471429,0.983834 beta-lactamase_2500_E145C,beta-lactamase_2500_145,TEM-1,beta-lactamase_2500,P62593,0.983834,NO,145,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.357,-5.044,2.687,,0.545,H,A,1.04,0.79,2.124,,77.62,BAH,-2.069,0.361275,0.00553285,0.983834 beta-lactamase_2500_G39S,beta-lactamase_2500_39,TEM-1,beta-lactamase_2500,P62593,0.983837,NO,39,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.864,-2.342,0.478,,0.701,T,L,0.29,0.47,29.926,29.926,77.62,HOH,-1.53633,0.361275,0.00487611,0.983837 Pab1_L133M,Pab1_133,Pab1,Pab1,P04147,0.983846,NO,133,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.039,-3.622,2.583,,0.015,,B,1.75,1.03,,,,PHB,-1.22,0.175299,0.000345939,0.983846 kka2_1:4_Q155H,kka2_1:4_155,Kka2,kka2_1:4,P00552,0.98385,NO,155,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.606,-4.51,1.904,,0.525,T,A,0.64,1.49,1.592,,63.64,APA,-1.726,0.168804,0.00641853,0.98385 beta-lactamase_2500_P172A,beta-lactamase_2500_172,TEM-1,beta-lactamase_2500,P62593,0.983854,NO,172,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.998,-2.44,1.442,,0.639,T,b,0.52,0.24,4.99,,74.48,HOP,-2.03067,0.361275,0.00312594,0.983854 beta-lactamase_0_G265P,beta-lactamase_0_265,TEM-1,beta-lactamase_0,P62593,0.983857,NO,265,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.0500837,0.00811926,0.983857 beta-lactamase_39_H156V,beta-lactamase_39_156,TEM-1,beta-lactamase_39,P62593,0.983868,NO,156,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-3.156,-3.735,0.579,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.0495842,0.00468596,0.983868 Ubiquitin_A28D,Ubiquitin_28,Uba1,Ubiquitin,P0CG48,0.983871,NO,28,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.895,-2.865,0.97,4.73736,0.369,H,A,,-0.11,,,,BHB,-1.47667,0.205827,0.000842053,0.983871 Ubiquitin_A46A,Ubiquitin_46,Uba1,Ubiquitin,P0CG48,0.983871,NO,46,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.77,-1.77,0,5.38761,0.398,T,L,2.34,-0.8,6.506,,51.09,HHO,-1.505,0.205827,0.000581142,0.983871 Ubiquitin_A46S,Ubiquitin_46,Uba1,Ubiquitin,P0CG48,0.983871,NO,46,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.77,-2.743,0.973,5.38761,0.398,T,L,2.34,-0.8,6.506,,51.09,HHO,-1.505,0.205827,0.000581142,0.983871 Ubiquitin_D21T,Ubiquitin_21,Uba1,Ubiquitin,P0CG48,0.983871,NO,21,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.193,-3.453,2.26,4.96432,0.165,,B,0.23,-0.53,1.013,,71.82,PAP,-1.35867,0.205827,0.000465257,0.983871 Ubiquitin_D39G,Ubiquitin_39,Uba1,Ubiquitin,P0CG48,0.983871,NO,39,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.792,-2.429,0.637,5.1607,0.433,G,A,,0.55,,,,OAP,-1.754,0.205827,0.00071409,0.983871 Ubiquitin_D52I,Ubiquitin_52,Uba1,Ubiquitin,P0CG48,0.983871,NO,52,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.43,-2.891,1.461,4.75143,0.421,T,A,,0.79,,,,AAO,-1.50267,0.205827,0.000806517,0.983871 Ubiquitin_E16V,Ubiquitin_16,Uba1,Ubiquitin,P0CG48,0.983871,NO,16,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.545,-3.702,2.157,5.07465,0.567,E,B,,0.59,,,,HAH,-1.31367,0.205827,0.000786769,0.983871 Ubiquitin_E18P,Ubiquitin_18,Uba1,Ubiquitin,P0CG48,0.983871,NO,18,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.696,-3.916,2.22,5.04795,0.545,,B,,0.03,,,,HAO,-1.78733,0.205827,0.000623342,0.983871 Ubiquitin_E51V,Ubiquitin_51,Uba1,Ubiquitin,P0CG48,0.983871,NO,51,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.534,-3.625,2.091,5.36711,0.545,,B,,0.72,,,,HAA,-1.357,0.205827,0.000868134,0.983871 Ubiquitin_E64S,Ubiquitin_64,Uba1,Ubiquitin,P0CG48,0.983871,NO,64,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.763,-3.38,1.617,5.084,0.54,T,l,,0.79,,,,BAP,-1.64433,0.205827,0.000817406,0.983871 Ubiquitin_F45F,Ubiquitin_45,Uba1,Ubiquitin,P0CG48,0.983871,NO,45,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.322,-1.322,0,4.80693,0.26,E,B,1.62,-0.99,1.531,,53.87,HHH,-1.55267,0.205827,0.000470401,0.983871 Ubiquitin_F45H,Ubiquitin_45,Uba1,Ubiquitin,P0CG48,0.983871,NO,45,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.322,-4.495,3.173,4.80693,0.26,E,B,1.62,-0.99,1.531,,53.87,HHH,-1.55267,0.205827,0.000470401,0.983871 Ubiquitin_G10G,Ubiquitin_10,Uba1,Ubiquitin,P0CG48,0.983871,NO,10,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.396,-1.396,,5.29806,0.115,S,l,,0.2,,,,POB,-1.38633,0.205827,0.000748953,0.983871 Ubiquitin_G75G,Ubiquitin_75,Uba1,Ubiquitin,P0CG48,0.983871,NO,75,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.613,-1.613,0,5.44099,0.552,T,A,0.73,0.9,4.017,,34.31,BOO,-1.66767,0.205827,0.000712673,0.983871 Ubiquitin_G76G,Ubiquitin_76,Uba1,Ubiquitin,P0CG48,0.983871,NO,76,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.651,-1.651,0,5.7647,0.23,,B,0.12,0.08,9.665,9.665,34.31,OOO,-1.632,0.205827,0.000653872,0.983871 Ubiquitin_H68H,Ubiquitin_68,Uba1,Ubiquitin,P0CG48,0.983871,NO,68,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-1.869,-1.869,0,4.81902,0.194,E,B,0.72,-1.02,21.325,21.325,65.11,HBH,-1.583,0.205827,0.000925438,0.983871 Ubiquitin_I13L,Ubiquitin_13,Uba1,Ubiquitin,P0CG48,0.983871,NO,13,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.554,-2.15,0.596,5.19411,0.038,E,B,,-0.2,,,,PHP,-1.48,0.205827,0.000716423,0.983871 Ubiquitin_I23I,Ubiquitin_23,Uba1,Ubiquitin,P0CG48,0.983871,NO,23,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.325,-1.325,,4.67534,,H,A,0.01,-0.93,0.515,,52.12,PHA,-1.54033,0.205827,0.000621252,0.983871 Ubiquitin_I23M,Ubiquitin_23,Uba1,Ubiquitin,P0CG48,0.983871,NO,23,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.325,-2.946,1.621,4.67534,,H,A,0.01,-0.93,0.515,,52.12,PHA,-1.54033,0.205827,0.000621252,0.983871 Ubiquitin_I30M,Ubiquitin_30,Uba1,Ubiquitin,P0CG48,0.983871,NO,30,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.205,-4.068,2.863,4.80264,,H,A,,-0.51,,,,BHP,-1.45133,0.205827,0.000720128,0.983871 Ubiquitin_I61L,Ubiquitin_61,Uba1,Ubiquitin,P0CG48,0.983871,NO,61,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.514,-2.228,0.714,5.19922,0.038,,B,1,-0.76,1.953,,24.53,PHP,-1.70833,0.205827,0.000738268,0.983871 Ubiquitin_I61M,Ubiquitin_61,Uba1,Ubiquitin,P0CG48,0.983871,NO,61,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.514,-3.111,1.597,5.19922,0.038,,B,1,-0.76,1.953,,24.53,PHP,-1.70833,0.205827,0.000738268,0.983871 Ubiquitin_K27K,Ubiquitin_27,Uba1,Ubiquitin,P0CG48,0.983871,NO,27,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.064,-1.064,0,4.77438,0.086,H,A,2.89,-0.74,2.662,,27.01,HBH,-1.42667,0.205827,0.000767556,0.983871 Ubiquitin_K29F,Ubiquitin_29,Uba1,Ubiquitin,P0CG48,0.983871,NO,29,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.471,-4.211,2.74,4.74832,0.355,H,A,,-0.06,,,,HBH,-1.52367,0.205827,0.000900239,0.983871 Ubiquitin_K29G,Ubiquitin_29,Uba1,Ubiquitin,P0CG48,0.983871,NO,29,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.471,-3.49,2.019,4.74832,0.355,H,A,,-0.06,,,,HBH,-1.52367,0.205827,0.000900239,0.983871 Ubiquitin_K29L,Ubiquitin_29,Uba1,Ubiquitin,P0CG48,0.983871,NO,29,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.471,-2.667,1.196,4.74832,0.355,H,A,,-0.06,,,,HBH,-1.52367,0.205827,0.000900239,0.983871 Ubiquitin_K29R,Ubiquitin_29,Uba1,Ubiquitin,P0CG48,0.983871,NO,29,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.471,-3.455,1.984,4.74832,0.355,H,A,,-0.06,,,,HBH,-1.52367,0.205827,0.000900239,0.983871 Ubiquitin_L15A,Ubiquitin_15,Uba1,Ubiquitin,P0CG48,0.983871,NO,15,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.082,-3.061,1.979,5.14718,0.029,E,B,1.16,-0.53,0.936,,38.69,PHA,-1.40833,0.205827,0.000519738,0.983871 Ubiquitin_L43I,Ubiquitin_43,Uba1,Ubiquitin,P0CG48,0.983871,NO,43,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.269,-2.15,0.881,4.8799,,E,B,1.75,-1.17,10.246,10.246,53.87,BHH,-1.46867,0.205827,0.000572481,0.983871 Ubiquitin_L69M,Ubiquitin_69,Uba1,Ubiquitin,P0CG48,0.983871,NO,69,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.445,-3.113,1.668,4.75624,0.051,E,B,2.89,-0.94,7.106,,34.31,BHH,-1.72933,0.205827,0.000919136,0.983871 Ubiquitin_L71L,Ubiquitin_71,Uba1,Ubiquitin,P0CG48,0.983871,NO,71,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.647,-1.647,0,5.02588,0.591,E,B,2.89,-0.69,4.365,,34.31,HHB,-1.85167,0.205827,0.000949314,0.983871 Ubiquitin_N25A,Ubiquitin_25,Uba1,Ubiquitin,P0CG48,0.983871,NO,25,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-1.95,-2.664,0.714,4.76563,0.444,H,A,0.09,0,2.3,,31.09,APH,-1.741,0.205827,0.00071919,0.983871 Ubiquitin_N25N,Ubiquitin_25,Uba1,Ubiquitin,P0CG48,0.983871,NO,25,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-1.95,-1.95,0,4.76563,0.444,H,A,0.09,0,2.3,,31.09,APH,-1.741,0.205827,0.00071919,0.983871 Ubiquitin_N25Q,Ubiquitin_25,Uba1,Ubiquitin,P0CG48,0.983871,NO,25,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-1.95,-2.768,0.818,4.76563,0.444,H,A,0.09,0,2.3,,31.09,APH,-1.741,0.205827,0.00071919,0.983871 Ubiquitin_N25R,Ubiquitin_25,Uba1,Ubiquitin,P0CG48,0.983871,NO,25,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-1.95,-3.747,1.797,4.76563,0.444,H,A,0.09,0,2.3,,31.09,APH,-1.741,0.205827,0.00071919,0.983871 Ubiquitin_N25T,Ubiquitin_25,Uba1,Ubiquitin,P0CG48,0.983871,NO,25,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-1.95,-2.804,0.854,4.76563,0.444,H,A,0.09,0,2.3,,31.09,APH,-1.741,0.205827,0.00071919,0.983871 Ubiquitin_N60A,Ubiquitin_60,Uba1,Ubiquitin,P0CG48,0.983871,NO,60,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-1.775,-2.683,0.908,5.00332,0.775,T,L,,0.33,,,,HPH,-1.532,0.205827,0.000814061,0.983871 Ubiquitin_N60S,Ubiquitin_60,Uba1,Ubiquitin,P0CG48,0.983871,NO,60,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-1.775,-2.393,0.618,5.00332,0.775,T,L,,0.33,,,,HPH,-1.532,0.205827,0.000814061,0.983871 Ubiquitin_P19I,Ubiquitin_19,Uba1,Ubiquitin,P0CG48,0.983871,NO,19,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-2.352,-3.897,1.545,4.67617,0.398,T,A,,-0.61,,,,AOP,-1.86233,0.205827,0.000729653,0.983871 Ubiquitin_P19M,Ubiquitin_19,Uba1,Ubiquitin,P0CG48,0.983871,NO,19,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-2.352,-4.693,2.341,4.67617,0.398,T,A,,-0.61,,,,AOP,-1.86233,0.205827,0.000729653,0.983871 Ubiquitin_P19R,Ubiquitin_19,Uba1,Ubiquitin,P0CG48,0.983871,NO,19,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-2.352,-3.065,0.713,4.67617,0.398,T,A,,-0.61,,,,AOP,-1.86233,0.205827,0.000729653,0.983871 Ubiquitin_P19Y,Ubiquitin_19,Uba1,Ubiquitin,P0CG48,0.983871,NO,19,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-2.352,-4.155,1.803,4.67617,0.398,T,A,,-0.61,,,,AOP,-1.86233,0.205827,0.000729653,0.983871 Ubiquitin_P37I,Ubiquitin_37,Uba1,Ubiquitin,P0CG48,0.983871,NO,37,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.275,-3.805,2.53,5.06918,0.323,,B,,-0.09,,,,HOO,-1.49,0.205827,0.000600764,0.983871 Ubiquitin_P37R,Ubiquitin_37,Uba1,Ubiquitin,P0CG48,0.983871,NO,37,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.275,-3.893,2.618,5.06918,0.323,,B,,-0.09,,,,HOO,-1.49,0.205827,0.000600764,0.983871 Ubiquitin_P37V,Ubiquitin_37,Uba1,Ubiquitin,P0CG48,0.983871,NO,37,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.275,-3.433,2.158,5.06918,0.323,,B,,-0.09,,,,HOO,-1.49,0.205827,0.000600764,0.983871 Ubiquitin_Q31K,Ubiquitin_31,Uba1,Ubiquitin,P0CG48,0.983871,NO,31,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-1.678,-2.625,0.947,4.5004,0.464,H,A,,0.68,,,,HPA,-1.44467,0.205827,0.000724141,0.983871 Ubiquitin_Q40Q,Ubiquitin_40,Uba1,Ubiquitin,P0CG48,0.983871,NO,40,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-1.752,-1.752,0,4.7807,0.387,G,A,,0.03,,,,APP,-1.62433,0.205827,0.000619089,0.983871 Ubiquitin_Q40T,Ubiquitin_40,Uba1,Ubiquitin,P0CG48,0.983871,NO,40,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-1.752,-3.55,1.798,4.7807,0.387,G,A,,0.03,,,,APP,-1.62433,0.205827,0.000619089,0.983871 Ubiquitin_Q41C,Ubiquitin_41,Uba1,Ubiquitin,P0CG48,0.983871,NO,41,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-1.329,-5.053,3.724,4.9201,0.017,E,B,0.12,-0.98,0.812,,30.07,PPB,-1.55067,0.205827,0.000521668,0.983871 Ubiquitin_Q62F,Ubiquitin_62,Uba1,Ubiquitin,P0CG48,0.983871,NO,62,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-1.836,-4.369,2.533,5.33616,0.762,,B,,0.79,,,,HPB,-1.66167,0.205827,0.00068944,0.983871 Ubiquitin_R54F,Ubiquitin_54,Uba1,Ubiquitin,P0CG48,0.983871,NO,54,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.037,-4.187,2.15,5.14935,0.41,S,B,,0.87,,,,OBP,-1.72667,0.205827,0.000581095,0.983871 Ubiquitin_R54N,Ubiquitin_54,Uba1,Ubiquitin,P0CG48,0.983871,NO,54,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.037,-2.931,0.894,5.14935,0.41,S,B,,0.87,,,,OBP,-1.72667,0.205827,0.000581095,0.983871 Ubiquitin_R54Q,Ubiquitin_54,Uba1,Ubiquitin,P0CG48,0.983871,NO,54,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.037,-3.866,1.829,5.14935,0.41,S,B,,0.87,,,,OBP,-1.72667,0.205827,0.000581095,0.983871 Ubiquitin_R54S,Ubiquitin_54,Uba1,Ubiquitin,P0CG48,0.983871,NO,54,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.037,-3.474,1.437,5.14935,0.41,S,B,,0.87,,,,OBP,-1.72667,0.205827,0.000581095,0.983871 Ubiquitin_S57D,Ubiquitin_57,Uba1,Ubiquitin,P0CG48,0.983871,NO,57,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.879,-3.645,1.766,4.65125,0.456,G,A,,-0.42,,,,HPA,-1.60833,0.205827,0.000948086,0.983871 Ubiquitin_S57V,Ubiquitin_57,Uba1,Ubiquitin,P0CG48,0.983871,NO,57,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.879,-2.794,0.915,4.65125,0.456,G,A,,-0.42,,,,HPA,-1.60833,0.205827,0.000948086,0.983871 Ubiquitin_S57Y,Ubiquitin_57,Uba1,Ubiquitin,P0CG48,0.983871,NO,57,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.879,-4.3,2.421,4.65125,0.456,G,A,,-0.42,,,,HPA,-1.60833,0.205827,0.000948086,0.983871 Ubiquitin_T12S,Ubiquitin_12,Uba1,Ubiquitin,P0CG48,0.983871,NO,12,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.288,-2.412,1.124,4.93973,0.417,E,B,0.8,0.12,2.762,,25.84,BPH,-1.39867,0.205827,0.000657544,0.983871 Ubiquitin_T14G,Ubiquitin_14,Uba1,Ubiquitin,P0CG48,0.983871,NO,14,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.598,-3.422,1.824,5.10811,0.345,E,B,,-0.37,,,,HPH,-1.41133,0.205827,0.000632754,0.983871 Ubiquitin_T55F,Ubiquitin_55,Uba1,Ubiquitin,P0CG48,0.983871,NO,55,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.599,-3.084,1.485,4.58329,0.173,B,B,,-0.68,,,,BPH,-1.65333,0.205827,0.000525703,0.983871 Ubiquitin_T55L,Ubiquitin_55,Uba1,Ubiquitin,P0CG48,0.983871,NO,55,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.599,-2.714,1.115,4.58329,0.173,B,B,,-0.68,,,,BPH,-1.65333,0.205827,0.000525703,0.983871 Ubiquitin_T55M,Ubiquitin_55,Uba1,Ubiquitin,P0CG48,0.983871,NO,55,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.599,-4.562,2.963,4.58329,0.173,B,B,,-0.68,,,,BPH,-1.65333,0.205827,0.000525703,0.983871 Ubiquitin_T55Y,Ubiquitin_55,Uba1,Ubiquitin,P0CG48,0.983871,NO,55,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.599,-3.094,1.495,4.58329,0.173,B,B,,-0.68,,,,BPH,-1.65333,0.205827,0.000525703,0.983871 Ubiquitin_T7A,Ubiquitin_7,Uba1,Ubiquitin,P0CG48,0.983871,NO,7,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.415,-3.015,1.6,4.954,0.094,E,B,0.43,-0.78,0.805,,21.31,BPH,-1.41033,0.205827,0.000647855,0.983871 Ubiquitin_T9T,Ubiquitin_9,Uba1,Ubiquitin,P0CG48,0.983871,NO,9,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.409,-1.409,,5.24336,0.777,T,A,2.12,-0.12,2.705,,29.93,HPO,-1.50933,0.205827,0.000630716,0.983871 Ubiquitin_V17G,Ubiquitin_17,Uba1,Ubiquitin,P0CG48,0.983871,NO,17,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.314,-3.568,2.254,5.26282,0.017,,B,2.78,-0.77,3.239,,71.82,AHA,-1.51833,0.205827,0.000659638,0.983871 Ubiquitin_V26V,Ubiquitin_26,Uba1,Ubiquitin,P0CG48,0.983871,NO,26,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.321,-1.321,0,4.78447,,H,A,,-0.97,,,,PHB,-1.445,0.205827,0.000980269,0.983871 Ubiquitin_V70V,Ubiquitin_70,Uba1,Ubiquitin,P0CG48,0.983871,NO,70,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.874,-1.874,0,5.29728,0.05,E,B,0.96,-0.97,2.363,,34.31,HHH,-1.65533,0.205827,0.00106871,0.983871 beta-lactamase_39_T178G,beta-lactamase_39_178,TEM-1,beta-lactamase_39,P62593,0.983877,NO,178,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-0.791,-3.358,2.567,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.0495842,0.000684366,0.983877 beta-lactamase_156_N130Q,beta-lactamase_156_130,TEM-1,beta-lactamase_156,P62593,0.983892,NO,130,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-0.798,-3.674,2.876,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.111618,0.000683376,0.983892 beta-lactamase_625_V82H,beta-lactamase_625_82,TEM-1,beta-lactamase_625,P62593,0.983897,NO,82,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.325,-4.872,3.547,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.213352,0.00397046,0.983897 kka2_1:8_A215T,kka2_1:8_215,Kka2,kka2_1:8,P00552,0.983907,NO,215,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.968,-2.586,1.618,,0.039,E,B,1.04,-0.59,2.77,,50.38,HHA,-1.00467,0.100394,0.00529129,0.983907 kka2_1:8_A215T,kka2_1:8_215,Kka2,kka2_1:8,P00552,0.983907,NO,215,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.968,-2.586,1.618,,0.039,E,B,1.04,-0.59,2.77,,50.38,HHA,-1.00467,0.100394,0.00529129,0.983907 beta-lactamase_39_N98H,beta-lactamase_39_98,TEM-1,beta-lactamase_39,P62593,0.98391,NO,98,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-2.973,-3.344,0.371,,0.963,G,A,0.61,1.35,14.853,14.853,77.62,PPA,-2.07867,0.0495842,0.00505389,0.98391 kka2_1:1_E3N,kka2_1:1_3,Kka2,kka2_1:1,P00552,0.983921,NO,3,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.199,-3.328,1.129,,,,,,,3.435,,92.05,HAP,-2.11567,0.520039,0.00267607,0.983921 beta-lactamase_E108G,beta-lactamase_108,TEM-1,beta-lactamase,P62593,0.983923,NO,108,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.46,-2.454,0.994,5.52079,0.572,G,A,0.52,1.87,1.973,,72.73,PAB,-1.437,0.221079,0.00413372,0.983923 beta-lactamase_156_H156I,beta-lactamase_156_156,TEM-1,beta-lactamase_156,P62593,0.983924,NO,156,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-3.156,-4.08,0.924,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.111618,0.00468596,0.983924 beta-lactamase_2500_M66L,beta-lactamase_2500_66,TEM-1,beta-lactamase_2500,P62593,0.983924,NO,66,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.362,-1.674,0.312,,0.013,,A,0.55,-0.7,0.502,,73.08,OHH,-1.49567,0.361275,0.00412876,0.983924 beta-lactamase_39_V101E,beta-lactamase_39_101,TEM-1,beta-lactamase_39,P62593,0.983927,NO,101,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.295,-2.851,1.556,,0.342,,B,0.44,0,2.96,,73.08,HHA,-1.54367,0.0495842,0.00374492,0.983927 beta-lactamase_156_L38M,beta-lactamase_156_38,TEM-1,beta-lactamase_156,P62593,0.983933,NO,38,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.343,-4.186,2.843,,0.088,H,A,0.55,0.2,13.556,13.556,64.34,PHO,-1.78033,0.111618,0.00373244,0.983933 beta-lactamase_39_L284E,beta-lactamase_39_284,TEM-1,beta-lactamase_39,P62593,0.983935,NO,284,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.0495842,0.0686156,0.983935 beta-lactamase_156_R176K,beta-lactamase_156_176,TEM-1,beta-lactamase_156,P62593,0.983938,NO,176,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-0.863,-2.782,1.919,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.111618,0.00105554,0.983938 beta-lactamase_156_F149K,beta-lactamase_156_149,TEM-1,beta-lactamase_156,P62593,0.983941,NO,149,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.299,-3.859,2.56,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.111618,0.00418462,0.983941 beta-lactamase_E62E,beta-lactamase_62,TEM-1,beta-lactamase,P62593,0.983942,NO,62,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.193,-1.193,,5.93066,0.342,S,B,1.52,-0.3,3.139,,73.08,AAB,-1.417,0.221079,0.00264802,0.983942 beta-lactamase_625_Q276T,beta-lactamase_625_276,TEM-1,beta-lactamase_625,P62593,0.983943,NO,276,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.213352,0.0191712,0.983943 beta-lactamase_156_W288H,beta-lactamase_156_288,TEM-1,beta-lactamase_156,P62593,0.983955,NO,288,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,,,,,,,,,,,,,BHO,,0.111618,,0.983955 beta-lactamase_L55L,beta-lactamase_55,TEM-1,beta-lactamase,P62593,0.983956,NO,55,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.86,-1.86,,,0.372,E,A,1.07,-0.36,1.423,,63.99,HHA,-2.247,0.221079,0.00403741,0.983956 beta-lactamase_625_N98V,beta-lactamase_625_98,TEM-1,beta-lactamase_625,P62593,0.983958,NO,98,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-2.973,-3.696,0.723,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.213352,0.00505389,0.983958 beta-lactamase_2500_A225N,beta-lactamase_2500_225,TEM-1,beta-lactamase_2500,P62593,0.983962,NO,225,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.845,-3.051,1.206,,1,T,B,0.46,-0.38,0.551,,74.48,OHO,-1.39967,0.361275,0.00465057,0.983962 beta-lactamase_156_N130G,beta-lactamase_156_130,TEM-1,beta-lactamase_156,P62593,0.983967,NO,130,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-0.798,-2.908,2.11,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.111618,0.000683376,0.983967 beta-lactamase_156_S57I,beta-lactamase_156_57,TEM-1,beta-lactamase_156,P62593,0.983968,NO,57,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.918,-3.825,1.907,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.111618,0.00492804,0.983968 kka2_1:8_P76R,kka2_1:8_76,Kka2,kka2_1:8,P00552,0.983976,NO,76,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.449,-4.026,2.577,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.100394,0.00625685,0.983976 kka2_1:8_P76R,kka2_1:8_76,Kka2,kka2_1:8,P00552,0.983976,NO,76,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.449,-4.026,2.577,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.100394,0.00625685,0.983976 beta-lactamase_39_A225N,beta-lactamase_39_225,TEM-1,beta-lactamase_39,P62593,0.983984,NO,225,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.845,-3.051,1.206,,1,T,B,0.46,-0.38,9.874,9.874,74.48,OHO,-1.39967,0.0495842,0.00465057,0.983984 beta-lactamase_156_A40Q,beta-lactamase_156_40,TEM-1,beta-lactamase_156,P62593,0.98399,NO,40,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.402,-4.1,2.698,,0.155,S,B,0.46,0.21,1.357,,73.78,OHB,-1.40267,0.111618,0.00490026,0.98399 beta-lactamase_156_L146A,beta-lactamase_156_146,TEM-1,beta-lactamase_156,P62593,0.983992,NO,146,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.462,-3.204,1.742,,0.007,H,A,0.55,-0.56,1.578,,64.69,AHP,-1.656,0.111618,0.00474542,0.983992 beta-lactamase_39_I258T,beta-lactamase_39_258,TEM-1,beta-lactamase_39,P62593,0.983993,NO,258,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.0495842,0.007931,0.983993 beta-lactamase_625_P105R,beta-lactamase_625_105,TEM-1,beta-lactamase_625,P62593,0.983995,NO,105,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.813,-3.93,3.117,,0.226,T,A,0.52,0.8,1.154,,63.29,POH,-1.01533,0.213352,0.0011981,0.983995 beta-lactamase_156_H151G,beta-lactamase_156_151,TEM-1,beta-lactamase_156,P62593,0.984005,NO,151,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-2.96,-2.515,-0.445,,0.594,H,A,0.17,0.1,1.401,,77.62,HBP,-2.34767,0.111618,0.00216946,0.984005 beta-lactamase_2500_K144S,beta-lactamase_2500_144,TEM-1,beta-lactamase_2500,P62593,0.984009,NO,144,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-2.388,-2.51,0.122,,0.863,H,A,2.34,1.27,0.515,,77.62,OBA,-1.904,0.361275,0.00481141,0.984009 beta-lactamase_H94S,beta-lactamase_94,TEM-1,beta-lactamase,P62593,0.984009,NO,94,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-2.5,-3.499,0.999,6.1507,0.776,,B,0.63,1.24,1.176,,77.62,HBH,-1.872,0.221079,0.00389226,0.984009 beta-lactamase_0_T198F,beta-lactamase_0_198,TEM-1,beta-lactamase_0,P62593,0.984011,NO,198,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.168,-4.258,2.09,,0.489,,B,0.22,-0.13,9.874,,73.78,HPH,-1.98767,0.0500837,0.004311,0.984011 beta-lactamase_0_V78Q,beta-lactamase_0_78,TEM-1,beta-lactamase_0,P62593,0.98402,NO,78,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.459,-4.26,2.801,,,H,A,0.44,-0.47,16.615,16.615,63.64,HHH,-1.17833,0.0500837,0.00492501,0.98402 beta-lactamase_D48E,beta-lactamase_48,TEM-1,beta-lactamase,P62593,0.984023,NO,48,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.101,-2.049,0.948,4.89966,0.189,E,B,0.23,0.21,1.281,,50.35,HAH,-1.62467,0.221079,0.0027273,0.984023 beta-lactamase_156_Y103Q,beta-lactamase_156_103,TEM-1,beta-lactamase_156,P62593,0.984024,NO,103,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-1.33,-2.924,1.594,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.111618,0.00443048,0.984024 Pab1_F146C,Pab1_146,Pab1,Pab1,P04147,0.984024,NO,146,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.149,-4.679,3.53,,0.006,H,A,,0.75,,,,PHP,-1.161,0.175299,0.000329265,0.984024 beta-lactamase_39_N168F,beta-lactamase_39_168,TEM-1,beta-lactamase_39,P62593,0.984028,NO,168,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-1.029,-4.27,3.241,,0.113,G,A,0.61,-0.4,0.822,,44.41,HPA,-1.13233,0.0495842,0.00288667,0.984028 beta-lactamase_625_L47Q,beta-lactamase_625_47,TEM-1,beta-lactamase_625,P62593,0.984028,NO,47,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.876,-3.17,1.294,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.213352,0.00439844,0.984028 beta-lactamase_625_D271W,beta-lactamase_625_271,TEM-1,beta-lactamase_625,P62593,0.984036,NO,271,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.213352,0.00752082,0.984036 beta-lactamase_625_M180C,beta-lactamase_625_180,TEM-1,beta-lactamase_625,P62593,0.984038,NO,180,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-2.795,-4.786,1.991,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.213352,0.00552048,0.984038 beta-lactamase_156_A268G,beta-lactamase_156_268,TEM-1,beta-lactamase_156,P62593,0.984039,NO,268,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.111618,0.0102525,0.984039 beta-lactamase_2500_A200C,beta-lactamase_2500_200,TEM-1,beta-lactamase_2500,P62593,0.984041,NO,200,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.878,-5.005,3.127,,0.757,H,A,0.46,-0.19,0.436,,77.62,HHP,-2.001,0.361275,0.0060056,0.984041 kka2_1:8_N58K,kka2_1:8_58,Kka2,kka2_1:8,P00552,0.984044,NO,58,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-2.641,-3.669,1.028,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.100394,0.00793425,0.984044 kka2_1:8_N58K,kka2_1:8_58,Kka2,kka2_1:8,P00552,0.984044,NO,58,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-2.641,-3.669,1.028,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.100394,0.00793425,0.984044 beta-lactamase_39_L146I,beta-lactamase_39_146,TEM-1,beta-lactamase_39,P62593,0.984046,NO,146,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.462,-2.631,1.169,,0.007,H,A,0.55,-0.56,1.953,,64.69,AHP,-1.656,0.0495842,0.00474542,0.984046 beta-lactamase_39_H94K,beta-lactamase_39_94,TEM-1,beta-lactamase_39,P62593,0.984048,NO,94,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-2.5,-2.567,0.067,,0.776,,B,0.17,1.24,11.583,11.583,77.62,HBH,-1.872,0.0495842,0.00389226,0.984048 beta-lactamase_39_N98I,beta-lactamase_39_98,TEM-1,beta-lactamase_39,P62593,0.984048,NO,98,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-2.973,-4.064,1.091,,0.963,G,A,0.61,1.35,14.853,14.853,77.62,PPA,-2.07867,0.0495842,0.00505389,0.984048 beta-lactamase_S57S,beta-lactamase_57,TEM-1,beta-lactamase,P62593,0.984048,NO,57,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.918,-1.918,,5.64201,0.352,E,B,0.25,-0.18,1.971,,72.73,APH,-2.29167,0.221079,0.00492804,0.984048 Pab1_I157V,Pab1_157,Pab1,Pab1,P04147,0.984049,NO,157,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.623,-1.374,-0.249,,,,,,,1.439,,79.72,BHH,-1.28667,0.175299,0.0018103,0.984049 beta-lactamase_2500_E145D,beta-lactamase_2500_145,TEM-1,beta-lactamase_2500,P62593,0.984051,NO,145,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.357,-3.52,1.163,,0.545,H,A,1.04,0.79,2.124,,77.62,BAH,-2.069,0.361275,0.00553285,0.984051 beta-lactamase_156_V82F,beta-lactamase_156_82,TEM-1,beta-lactamase_156,P62593,0.984052,NO,82,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.325,-3.991,2.666,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.111618,0.00397046,0.984052 beta-lactamase_39_G253W,beta-lactamase_39_253,TEM-1,beta-lactamase_39,P62593,0.984053,NO,253,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.0495842,0.00786358,0.984053 beta-lactamase_625_E279W,beta-lactamase_625_279,TEM-1,beta-lactamase_625,P62593,0.984054,NO,279,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.213352,0.0192826,0.984054 beta-lactamase_625_S283T,beta-lactamase_625_283,TEM-1,beta-lactamase_625,P62593,0.984063,NO,283,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.213352,0.0429138,0.984063 PSD95pdz3_L360S,PSD95pdz3_360,PSD95pdz3,PSD95pdz3,P31016,0.984065,NO,360,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.431,-3.291,1.86,5.09284,,,,,14.2425,1.419,,86.88,HHP,-1.52667,0.0758425,0.000770471,0.984065 beta-lactamase_39_E56L,beta-lactamase_39_56,TEM-1,beta-lactamase_39,P62593,0.984066,NO,56,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.043,-3.398,1.355,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.0495842,0.00238534,0.984066 beta-lactamase_P172I,beta-lactamase_172,TEM-1,beta-lactamase,P62593,0.98407,NO,172,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.998,-3.854,2.856,5.98941,0.639,T,b,1.1,0.24,2.087,,74.48,HOP,-2.03067,0.221079,0.00312594,0.98407 beta-lactamase_S221N,beta-lactamase_221,TEM-1,beta-lactamase,P62593,0.98407,NO,221,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.754,-3.696,1.942,5.77407,0.624,H,A,0.74,-0.2,0.383,,74.48,BPH,-1.59967,0.221079,0.0046094,0.98407 beta-lactamase_156_E169N,beta-lactamase_156_169,TEM-1,beta-lactamase_156,P62593,0.984075,NO,169,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.23,-3.55,2.32,,0.337,,A,1.04,1,3.516,,73.08,PAH,-1.16533,0.111618,0.00400994,0.984075 beta-lactamase_2500_H110F,beta-lactamase_2500_110,TEM-1,beta-lactamase_2500,P62593,0.984085,NO,110,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-1.706,-4.019,2.313,,0.341,G,a,0.17,1.08,31.31,31.31,64.69,BBH,-1.73333,0.361275,0.00441499,0.984085 beta-lactamase_625_R159C,beta-lactamase_625_159,TEM-1,beta-lactamase_625,P62593,0.984091,NO,159,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-0.94,-5.113,4.173,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.213352,0.00108472,0.984091 beta-lactamase_2500_A133G,beta-lactamase_2500_133,TEM-1,beta-lactamase_2500,P62593,0.984092,NO,133,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.186,-1.519,0.333,,,H,A,0.46,-0.86,2.649,,67.83,HHP,-0.988333,0.361275,0.00468022,0.984092 beta-lactamase_156_E272G,beta-lactamase_156_272,TEM-1,beta-lactamase_156,P62593,0.984098,NO,272,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.111618,0.00545371,0.984098 beta-lactamase_156_Y262C,beta-lactamase_156_262,TEM-1,beta-lactamase_156,P62593,0.984099,NO,262,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.111618,0.00853516,0.984099 beta-lactamase_39_Q276I,beta-lactamase_39_276,TEM-1,beta-lactamase_39,P62593,0.984099,NO,276,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.0495842,0.0191712,0.984099 beta-lactamase_156_E61G,beta-lactamase_156_61,TEM-1,beta-lactamase_156,P62593,0.984101,NO,61,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.115,-2.393,0.278,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.111618,0.00440955,0.984101 beta-lactamase_156_M153W,beta-lactamase_156_153,TEM-1,beta-lactamase_156,P62593,0.984104,NO,153,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-3.193,-5.376,2.183,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.111618,0.00509109,0.984104 beta-lactamase_P172M,beta-lactamase_172,TEM-1,beta-lactamase,P62593,0.984104,NO,172,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.998,-4.616,3.618,5.98941,0.639,T,b,1.1,0.24,2.087,,74.48,HOP,-2.03067,0.221079,0.00312594,0.984104 beta-lactamase_0_L55N,beta-lactamase_0_55,TEM-1,beta-lactamase_0,P62593,0.984108,NO,55,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.86,-4.216,2.356,,0.372,E,A,0.55,-0.36,1.967,,63.99,HHA,-2.247,0.0500837,0.00403741,0.984108 beta-lactamase_39_A247I,beta-lactamase_39_247,TEM-1,beta-lactamase_39,P62593,0.984113,NO,247,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.0495842,0.00611275,0.984113 beta-lactamase_625_V214I,beta-lactamase_625_214,TEM-1,beta-lactamase_625,P62593,0.984113,NO,214,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.299,-3.053,1.754,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.213352,0.00628442,0.984113 beta-lactamase_625_W288Y,beta-lactamase_625_288,TEM-1,beta-lactamase_625,P62593,0.984113,NO,288,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,,,,,,,,,,,,,BHO,,0.213352,,0.984113 beta-lactamase_156_D161Y,beta-lactamase_156_161,TEM-1,beta-lactamase_156,P62593,0.984114,NO,161,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.891,-4.387,3.496,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.111618,0.000897697,0.984114 beta-lactamase_625_L146I,beta-lactamase_625_146,TEM-1,beta-lactamase_625,P62593,0.984115,NO,146,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.462,-2.631,1.169,,0.007,H,A,0.55,-0.56,2.16,,64.69,AHP,-1.656,0.213352,0.00474542,0.984115 beta-lactamase_156_H24I,beta-lactamase_156_24,TEM-1,beta-lactamase_156,P62593,0.984119,NO,24,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-2.481,-3.874,1.393,,,,,,,2.708,,93.01,OBO,-2.0035,0.111618,0.00238894,0.984119 beta-lactamase_2500_A77Q,beta-lactamase_2500_77,TEM-1,beta-lactamase_2500,P62593,0.984126,NO,77,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.234,-4.052,2.818,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.361275,0.00282362,0.984126 beta-lactamase_0_K286Y,beta-lactamase_0_286,TEM-1,beta-lactamase_0,P62593,0.984139,NO,286,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.0500837,,0.984139 beta-lactamase_0_L196D,beta-lactamase_0_196,TEM-1,beta-lactamase_0,P62593,0.984151,NO,196,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-2.478,-3.862,1.384,,0.518,S,A,0.55,1.35,6.513,6.513,77.62,AHH,-1.839,0.0500837,0.00512144,0.984151 beta-lactamase_K144V,beta-lactamase_144,TEM-1,beta-lactamase,P62593,0.984152,NO,144,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-2.388,-3.003,0.615,6.02507,0.863,H,A,2.81,1.27,0.515,,77.62,OBA,-1.904,0.221079,0.00481141,0.984152 beta-lactamase_2500_N98Q,beta-lactamase_2500_98,TEM-1,beta-lactamase_2500,P62593,0.984156,NO,98,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-2.973,-2.336,-0.637,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.361275,0.00505389,0.984156 beta-lactamase_0_I261T,beta-lactamase_0_261,TEM-1,beta-lactamase_0,P62593,0.98416,NO,261,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-2.88,-1.929,-0.951,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.0500837,0.0123091,0.98416 beta-lactamase_156_K30N,beta-lactamase_156_30,TEM-1,beta-lactamase_156,P62593,0.98416,NO,30,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-2.307,-2.865,0.558,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.111618,0.00448593,0.98416 kka2_1:4_Q26D,kka2_1:4_26,Kka2,kka2_1:4,P00552,0.984162,NO,26,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.18,-3.048,0.868,,0.448,E,B,0.4,0.44,5.022,,92.05,HPP,-2.11167,0.168804,0.00708962,0.984162 beta-lactamase_156_A200E,beta-lactamase_156_200,TEM-1,beta-lactamase_156,P62593,0.984165,NO,200,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.878,-2.662,0.784,,0.757,H,A,0.46,-0.19,16.368,16.368,77.62,HHP,-2.001,0.111618,0.0060056,0.984165 beta-lactamase_156_M153S,beta-lactamase_156_153,TEM-1,beta-lactamase_156,P62593,0.984166,NO,153,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-3.193,-2.433,-0.76,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.111618,0.00509109,0.984166 beta-lactamase_0_N98G,beta-lactamase_0_98,TEM-1,beta-lactamase_0,P62593,0.984177,NO,98,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-2.973,-3.401,0.428,,0.963,G,A,0.61,1.35,14.853,14.853,77.62,PPA,-2.07867,0.0500837,0.00505389,0.984177 beta-lactamase_625_H287N,beta-lactamase_625_287,TEM-1,beta-lactamase_625,P62593,0.984181,NO,287,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,,,,,,,,,,,,,BBH,-1.111,0.213352,,0.984181 kka2_1:8_F206M,kka2_1:8_206,Kka2,kka2_1:8,P00552,0.984182,NO,206,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.349,-3.155,1.806,,0.006,E,B,1.62,-1.21,1.052,,63.64,OHH,-1.04,0.100394,0.00936868,0.984182 kka2_1:8_F206M,kka2_1:8_206,Kka2,kka2_1:8,P00552,0.984182,NO,206,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.349,-3.155,1.806,,0.006,E,B,1.62,-1.21,1.052,,63.64,OHH,-1.04,0.100394,0.00936868,0.984182 beta-lactamase_625_T107L,beta-lactamase_625_107,TEM-1,beta-lactamase_625,P62593,0.984184,NO,107,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.117,-3.237,2.12,,,G,A,0.22,-0.06,3.676,,67.83,HPA,-1.265,0.213352,0.00239347,0.984184 beta-lactamase_156_P172Q,beta-lactamase_156_172,TEM-1,beta-lactamase_156,P62593,0.984189,NO,172,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.998,-3.965,2.967,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.111618,0.00312594,0.984189 beta-lactamase_T27T,beta-lactamase_27,TEM-1,beta-lactamase,P62593,0.984189,NO,27,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.905,-1.905,,5.39752,0.007,H,A,0.69,-0.37,0.745,,93.01,APH,-1.97933,0.221079,0.00306559,0.984189 beta-lactamase_156_A278S,beta-lactamase_156_278,TEM-1,beta-lactamase_156,P62593,0.984199,NO,278,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.111618,0.0310297,0.984199 beta-lactamase_156_S57M,beta-lactamase_156_57,TEM-1,beta-lactamase_156,P62593,0.984205,NO,57,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.918,-4.684,2.766,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.111618,0.00492804,0.984205 beta-lactamase_156_R59Q,beta-lactamase_156_59,TEM-1,beta-lactamase_156,P62593,0.984208,NO,59,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.345,-2.612,1.267,,0.329,S,L,1.2,-0.09,2.995,,73.08,HBO,-2.24267,0.111618,0.00318082,0.984208 beta-lactamase_156_D231C,beta-lactamase_156_231,TEM-1,beta-lactamase_156,P62593,0.98421,NO,231,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.816,-5.136,4.32,,,E,B,0.75,-1.06,2.66,,65.38,HAB,-0.994,0.111618,0.00107395,0.98421 beta-lactamase_625_E62V,beta-lactamase_625_62,TEM-1,beta-lactamase_625,P62593,0.98421,NO,62,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.193,-3.636,2.443,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.213352,0.00264802,0.98421 beta-lactamase_625_D48N,beta-lactamase_625_48,TEM-1,beta-lactamase_625,P62593,0.98422,NO,48,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.101,-3.389,2.288,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.213352,0.0027273,0.98422 beta-lactamase_39_T131K,beta-lactamase_39_131,TEM-1,beta-lactamase_39,P62593,0.984221,NO,131,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.328,-3.481,2.153,,,H,A,0.22,-0.69,3.306,,67.48,PPH,-1.00867,0.0495842,0.00345886,0.984221 beta-lactamase_39_L137W,beta-lactamase_39_137,TEM-1,beta-lactamase_39,P62593,0.984224,NO,137,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.03,-5.164,4.134,,,H,A,0.55,-0.38,0.674,,42.31,HHP,-1.58933,0.0495842,0.00278599,0.984224 beta-lactamase_39_P255C,beta-lactamase_39_255,TEM-1,beta-lactamase_39,P62593,0.984224,NO,255,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.0495842,0.00499612,0.984224 kka2_1:8_A255V,kka2_1:8_255,Kka2,kka2_1:8,P00552,0.984234,NO,255,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.715,-3.655,1.94,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.100394,0.0126809,0.984234 kka2_1:8_A255V,kka2_1:8_255,Kka2,kka2_1:8,P00552,0.984234,NO,255,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.715,-3.655,1.94,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.100394,0.0126809,0.984234 beta-lactamase_39_E119L,beta-lactamase_39_119,TEM-1,beta-lactamase_39,P62593,0.984254,NO,119,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.412,-3.669,2.257,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.0495842,0.00386966,0.984254 beta-lactamase_39_T179I,beta-lactamase_39_179,TEM-1,beta-lactamase_39,P62593,0.984254,NO,179,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.085,-3.69,2.605,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.0495842,0.00226045,0.984254 beta-lactamase_156_T263N,beta-lactamase_156_263,TEM-1,beta-lactamase_156,P62593,0.984255,NO,263,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.111618,0.0110582,0.984255 beta-lactamase_156_D174N,beta-lactamase_156_174,TEM-1,beta-lactamase_156,P62593,0.98426,NO,174,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.738,-3.223,2.485,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.111618,0.00125633,0.98426 beta-lactamase_T267N,beta-lactamase_267,TEM-1,beta-lactamase,P62593,0.98426,NO,267,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.308,-2.521,0.213,5.28263,0.54,,B,0.69,-0.14,0.374,,73.78,HPH,-1.9,0.221079,0.0102128,0.98426 beta-lactamase_39_Q204G,beta-lactamase_39_204,TEM-1,beta-lactamase_39,P62593,0.984265,NO,204,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-1.382,-3.474,2.092,,0.204,H,A,0.64,0.09,0.489,,66.08,PPH,-1.49067,0.0495842,0.00364106,0.984265 beta-lactamase_625_R275W,beta-lactamase_625_275,TEM-1,beta-lactamase_625,P62593,0.984275,NO,275,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.213352,0.0141984,0.984275 beta-lactamase_625_R81G,beta-lactamase_625_81,TEM-1,beta-lactamase_625,P62593,0.984284,NO,81,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.466,-2.66,1.194,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.213352,0.00499763,0.984284 beta-lactamase_39_M184L,beta-lactamase_39_184,TEM-1,beta-lactamase_39,P62593,0.984287,NO,184,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.593,-2.806,1.213,,,H,A,0.55,-0.87,2.893,,62.94,HHH,-1.41,0.0495842,0.00356019,0.984287 beta-lactamase_156_T158G,beta-lactamase_156_158,TEM-1,beta-lactamase_156,P62593,0.984288,NO,158,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.116,-3.288,2.172,,0.036,,B,0.22,-0.85,3.771,,69.58,HPB,-1.269,0.111618,0.00341825,0.984288 beta-lactamase_2500_G39H,beta-lactamase_2500_39,TEM-1,beta-lactamase_2500,P62593,0.984288,NO,39,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.864,-3.359,1.495,,0.701,T,L,0.29,0.47,29.926,29.926,77.62,HOH,-1.53633,0.361275,0.00487611,0.984288 beta-lactamase_156_E62W,beta-lactamase_156_62,TEM-1,beta-lactamase_156,P62593,0.984289,NO,62,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.193,-5.409,4.216,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.111618,0.00264802,0.984289 beta-lactamase_39_T198V,beta-lactamase_39_198,TEM-1,beta-lactamase_39,P62593,0.984295,NO,198,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.168,-2.827,0.659,,0.489,,B,0.22,-0.13,3.614,,73.78,HPH,-1.98767,0.0495842,0.004311,0.984295 beta-lactamase_39_P181M,beta-lactamase_39_181,TEM-1,beta-lactamase_39,P62593,0.984296,NO,181,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.813,-4.702,3.889,,,H,A,0.52,-1.14,1.946,,61.54,HOH,-1.795,0.0495842,0.000703122,0.984296 beta-lactamase_T193T,beta-lactamase_193,TEM-1,beta-lactamase,P62593,0.984297,NO,193,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.914,-1.914,,5.67952,0.439,H,a,0.3,0.33,1.863,,63.99,HPO,-1.52133,0.221079,0.00482669,0.984297 beta-lactamase_39_A34H,beta-lactamase_39_34,TEM-1,beta-lactamase_39,P62593,0.984306,NO,34,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.059,-4.883,2.824,,,H,A,0.46,-0.54,13.292,13.292,73.78,AHA,-1.74967,0.0495842,0.00407913,0.984306 beta-lactamase_156_Q86A,beta-lactamase_156_86,TEM-1,beta-lactamase_156,P62593,0.984318,NO,86,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.4,-2.601,0.201,,0.696,S,A,0.64,2.38,27.704,27.704,77.62,OPA,-1.61067,0.111618,0.00450027,0.984318 beta-lactamase_2500_A222T,beta-lactamase_2500_222,TEM-1,beta-lactamase_2500,P62593,0.984324,NO,222,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.103,-2.805,0.702,,0.233,H,A,0.46,-0.25,0.379,,77.62,PHH,-1.63733,0.361275,0.00466094,0.984324 PSD95pdz3_E331W,PSD95pdz3_331,PSD95pdz3,PSD95pdz3,P31016,0.984327,NO,331,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.404,-5.004,3.6,5.86289,,,,,51.8889,,,,OAA,-1.22533,0.0758425,0.000950134,0.984327 beta-lactamase_156_E272H,beta-lactamase_156_272,TEM-1,beta-lactamase_156,P62593,0.984329,NO,272,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.111618,0.00545371,0.984329 beta-lactamase_39_S122Y,beta-lactamase_39_122,TEM-1,beta-lactamase_39,P62593,0.984333,NO,122,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.406,-4.156,1.75,,0.352,H,A,0.27,-0.54,2.004,,77.62,OPH,-1.39767,0.0495842,0.00497825,0.984333 beta-lactamase_625_P165A,beta-lactamase_625_165,TEM-1,beta-lactamase_625,P62593,0.984333,NO,165,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.373,-3.022,1.649,,0.203,T,A,0.52,-0.31,0.414,,73.78,AOA,-1.359,0.213352,0.00549538,0.984333 beta-lactamase_156_E169Y,beta-lactamase_156_169,TEM-1,beta-lactamase_156,P62593,0.984336,NO,169,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.23,-4.247,3.017,,0.337,,A,1.04,1,3.516,,73.08,PAH,-1.16533,0.111618,0.00400994,0.984336 beta-lactamase_156_H94E,beta-lactamase_156_94,TEM-1,beta-lactamase_156,P62593,0.984345,NO,94,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-2.5,-2.415,-0.085,,0.776,,B,0.17,1.24,11.583,11.583,77.62,HBH,-1.872,0.111618,0.00389226,0.984345 beta-lactamase_625_G194V,beta-lactamase_625_194,TEM-1,beta-lactamase_625,P62593,0.984345,NO,194,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.396,-3.736,2.34,,0.276,S,b,0.29,0.36,3.593,,67.83,POA,-1.832,0.213352,0.00392163,0.984345 beta-lactamase_156_D231I,beta-lactamase_156_231,TEM-1,beta-lactamase_156,P62593,0.984347,NO,231,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.816,-4.036,3.22,,,E,B,0.75,-1.06,2.66,,65.38,HAB,-0.994,0.111618,0.00107395,0.984347 beta-lactamase_2500_L160V,beta-lactamase_2500_160,TEM-1,beta-lactamase_2500,P62593,0.984353,NO,160,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.977,-2.271,1.294,,0.022,,B,0.55,-0.6,0.895,,44.41,BHA,-0.936,0.361275,0.00193775,0.984353 beta-lactamase_625_M270F,beta-lactamase_625_270,TEM-1,beta-lactamase_625,P62593,0.984369,NO,270,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.213352,0.00767762,0.984369 beta-lactamase_39_A148S,beta-lactamase_39_148,TEM-1,beta-lactamase_39,P62593,0.98437,NO,148,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.757,-2.791,1.034,,0.379,H,A,0.46,-0.55,3.551,,72.73,PHH,-1.40167,0.0495842,0.00547053,0.98437 PSD95pdz3_G364K,PSD95pdz3_364,PSD95pdz3,PSD95pdz3,P31016,0.984377,NO,364,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.008,-3.364,2.356,5.53299,,,,,21.28,,,,POH,-1.33667,0.0758425,0.00050942,0.984377 beta-lactamase_0_A230L,beta-lactamase_0_230,TEM-1,beta-lactamase_0,P62593,0.984378,NO,230,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.154,-3.416,2.262,,0.01,E,B,0.46,-1.17,2.179,,50,HHA,-1.079,0.0500837,0.00516841,0.984378 beta-lactamase_625_L167N,beta-lactamase_625_167,TEM-1,beta-lactamase_625,P62593,0.984378,NO,167,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.138,-4.008,2.87,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.213352,0.00303566,0.984378 beta-lactamase_156_D33S,beta-lactamase_156_33,TEM-1,beta-lactamase_156,P62593,0.984379,NO,33,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.321,-2.627,0.306,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.111618,0.00435556,0.984379 Pab1_K180N,Pab1_180,Pab1,Pab1,P04147,0.984379,NO,180,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.945,-2.639,0.694,,,,,,,,,,HBA,-1.575,0.175299,0.00295933,0.984379 beta-lactamase_625_F228N,beta-lactamase_625_228,TEM-1,beta-lactamase_625,P62593,0.98438,NO,228,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-2.342,-3.038,0.696,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.213352,0.0046669,0.98438 beta-lactamase_156_G265K,beta-lactamase_156_265,TEM-1,beta-lactamase_156,P62593,0.984381,NO,265,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.111618,0.00811926,0.984381 beta-lactamase_39_S233V,beta-lactamase_39_233,TEM-1,beta-lactamase_39,P62593,0.984381,NO,233,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.886,-3.357,1.471,,0.016,E,B,0.27,-1.01,5.361,,77.62,BPO,-1.17267,0.0495842,0.00311415,0.984381 beta-lactamase_39_R81G,beta-lactamase_39_81,TEM-1,beta-lactamase_39,P62593,0.984384,NO,81,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.466,-2.66,1.194,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.0495842,0.00499763,0.984384 beta-lactamase_156_M180C,beta-lactamase_156_180,TEM-1,beta-lactamase_156,P62593,0.984386,NO,180,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-2.795,-4.786,1.991,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.111618,0.00552048,0.984386 beta-lactamase_2500_A278Q,beta-lactamase_2500_278,TEM-1,beta-lactamase_2500,P62593,0.984387,NO,278,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.361275,0.0310297,0.984387 beta-lactamase_156_G226L,beta-lactamase_156_226,TEM-1,beta-lactamase_156,P62593,0.984388,NO,226,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.461,-3.765,2.304,,0.701,T,l,0.29,-0.25,3.199,,74.48,HOH,-1.42933,0.111618,0.00665294,0.984388 beta-lactamase_156_T263I,beta-lactamase_156_263,TEM-1,beta-lactamase_156,P62593,0.984391,NO,263,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.111618,0.0110582,0.984391 beta-lactamase_39_I280F,beta-lactamase_39_280,TEM-1,beta-lactamase_39,P62593,0.984398,NO,280,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.0495842,0.0530888,0.984398 beta-lactamase_39_T198K,beta-lactamase_39_198,TEM-1,beta-lactamase_39,P62593,0.984401,NO,198,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.168,-2.548,0.38,,0.489,,B,0.22,-0.13,3.614,,73.78,HPH,-1.98767,0.0495842,0.004311,0.984401 beta-lactamase_625_K30I,beta-lactamase_625_30,TEM-1,beta-lactamase_625,P62593,0.984403,NO,30,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-2.307,-3.856,1.549,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.213352,0.00448593,0.984403 beta-lactamase_39_G52D,beta-lactamase_39_52,TEM-1,beta-lactamase_39,P62593,0.984407,NO,52,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.149,-2.123,0.974,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.0495842,0.00340138,0.984407 Pab1_G188E,Pab1_188,Pab1,Pab1,P04147,0.984426,NO,188,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.809,-3.482,2.673,,0.379,E,g,,2.18,,,,POH,-1.14633,0.175299,0.000280911,0.984426 beta-lactamase_2500_D113N,beta-lactamase_2500_113,TEM-1,beta-lactamase_2500,P62593,0.984436,NO,113,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.829,-3.682,1.853,,0.665,T,A,0.75,0.91,21.104,21.104,73.08,PAO,-1.703,0.361275,0.00474112,0.984436 kka2_1:2_H139Y,kka2_1:2_139,Kka2,kka2_1:2,P00552,0.98444,NO,139,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-2.809,-3.482,0.673,,0.471,H,A,0.87,0.68,13.912,13.912,63.64,BBB,-2.22,0.295029,0.00734779,0.98444 beta-lactamase_156_G85C,beta-lactamase_156_85,TEM-1,beta-lactamase_156,P62593,0.984448,NO,85,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.011,-5.172,4.161,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.111618,0.00252173,0.984448 beta-lactamase_156_L199H,beta-lactamase_156_199,TEM-1,beta-lactamase_156,P62593,0.984452,NO,199,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-2.942,-4.8,1.858,,0.832,H,A,0.55,0.42,1.552,,77.62,PHH,-2.32933,0.111618,0.0048649,0.984452 beta-lactamase_39_E169A,beta-lactamase_39_169,TEM-1,beta-lactamase_39,P62593,0.984457,NO,169,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.23,-2.486,1.256,,0.337,,A,1.04,1,15.633,15.633,73.08,PAH,-1.16533,0.0495842,0.00400994,0.984457 beta-lactamase_156_G253T,beta-lactamase_156_253,TEM-1,beta-lactamase_156,P62593,0.984459,NO,253,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.111618,0.00786358,0.984459 beta-lactamase_156_K53E,beta-lactamase_156_53,TEM-1,beta-lactamase_156,P62593,0.98446,NO,53,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-2.313,-2.655,0.342,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.111618,0.00383383,0.98446 beta-lactamase_L167M,beta-lactamase_167,TEM-1,beta-lactamase,P62593,0.984462,NO,167,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.138,-2.673,1.535,5.13111,0.015,G,A,0.08,-0.63,0.4,,64.69,AHP,-1.30767,0.221079,0.00303566,0.984462 beta-lactamase_625_Q203Y,beta-lactamase_625_203,TEM-1,beta-lactamase_625,P62593,0.984465,NO,203,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.168,-4.35,2.182,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.213352,0.00631514,0.984465 beta-lactamase_39_Q204N,beta-lactamase_39_204,TEM-1,beta-lactamase_39,P62593,0.984469,NO,204,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-1.382,-3.623,2.241,,0.204,H,A,0.64,0.09,0.489,,66.08,PPH,-1.49067,0.0495842,0.00364106,0.984469 beta-lactamase_625_L191T,beta-lactamase_625_191,TEM-1,beta-lactamase_625,P62593,0.98447,NO,191,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.087,-3.447,2.36,,,H,A,0.55,0.09,1.908,,63.29,BHH,-1.445,0.213352,0.00263549,0.98447 beta-lactamase_0_P60R,beta-lactamase_0_60,TEM-1,beta-lactamase_0,P62593,0.984474,NO,60,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-2.469,-3.014,0.545,,0.256,T,A,0.52,-0.56,3.653,,77.62,BOA,-1.97633,0.0500837,0.00521318,0.984474 beta-lactamase_0_D177V,beta-lactamase_0_177,TEM-1,beta-lactamase_0,P62593,0.984481,NO,177,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.967,-3.739,2.772,,0.006,T,L,0.75,-1.02,3.536,,64.69,BAP,-0.873667,0.0500837,0.000864022,0.984481 beta-lactamase_39_E169F,beta-lactamase_39_169,TEM-1,beta-lactamase_39,P62593,0.984487,NO,169,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.23,-4.322,3.092,,0.337,,A,1.04,1,15.633,15.633,73.08,PAH,-1.16533,0.0495842,0.00400994,0.984487 beta-lactamase_156_A182D,beta-lactamase_156_182,TEM-1,beta-lactamase_156,P62593,0.984488,NO,182,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.777,-2.705,0.928,,0.136,H,A,0.46,-0.66,16.784,16.784,93.01,OHH,-1.27367,0.111618,0.00559099,0.984488 PSD95pdz3_N363A,PSD95pdz3_363,PSD95pdz3,PSD95pdz3,P31016,0.984488,NO,363,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-1.41,-2.984,1.574,5.23349,,,,,20.7037,,,,HPO,-1.29433,0.0758425,0.000524014,0.984488 Pab1_G177S,Pab1_177,Pab1,Pab1,P04147,0.98449,NO,177,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-2.24,-2.122,-0.118,,,,,,,,,,AOH,-1.94067,0.175299,0.00170727,0.98449 Pab1_F170Y,Pab1_170,Pab1,Pab1,P04147,0.984505,NO,170,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.269,-2.031,0.762,,0.331,E,B,0.87,-1.31,2.061,,79.72,OHH,-1.06367,0.175299,0.000540225,0.984505 beta-lactamase_0_A183W,beta-lactamase_0_183,TEM-1,beta-lactamase_0,P62593,0.984507,NO,183,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.231,-5.466,4.235,,0.155,H,A,0.46,-0.91,1.48,,77.62,HHH,-1.53367,0.0500837,0.00296631,0.984507 beta-lactamase_156_G226S,beta-lactamase_156_226,TEM-1,beta-lactamase_156,P62593,0.984507,NO,226,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.461,-2.74,1.279,,0.701,T,l,0.29,-0.25,3.199,,74.48,HOH,-1.42933,0.111618,0.00665294,0.984507 beta-lactamase_39_L28E,beta-lactamase_39_28,TEM-1,beta-lactamase_39,P62593,0.984511,NO,28,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.579,-3.677,2.098,,0.277,H,A,0.55,-0.16,3.262,,93.01,PHH,-2.11333,0.0495842,0.00359321,0.984511 beta-lactamase_156_R242K,beta-lactamase_156_242,TEM-1,beta-lactamase_156,P62593,0.984515,NO,242,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.111618,0.00452879,0.984515 Pab1_E176L,Pab1_176,Pab1,Pab1,P04147,0.984517,NO,176,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.003,-3.53,1.527,,,,,,,,,,AAO,-2.09933,0.175299,0.00264426,0.984517 beta-lactamase_625_T139G,beta-lactamase_625_139,TEM-1,beta-lactamase_625,P62593,0.984523,NO,139,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.901,-3.413,1.512,,0.216,H,A,0.22,0.39,2.256,,77.62,PPH,-2.04667,0.213352,0.00441837,0.984523 beta-lactamase_0_S256K,beta-lactamase_0_256,TEM-1,beta-lactamase_0,P62593,0.984525,NO,256,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.0500837,0.00710634,0.984525 beta-lactamase_2500_D99E,beta-lactamase_2500_99,TEM-1,beta-lactamase_2500,P62593,0.984529,NO,99,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.191,-2.122,0.931,,0.402,G,A,0.75,0.36,1.318,,64.69,PAH,-1.794,0.361275,0.00305446,0.984529 PSD95pdz3_R368I,PSD95pdz3_368,PSD95pdz3,PSD95pdz3,P31016,0.984529,NO,368,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.582,-3.692,2.11,6.13355,,,,,18.1818,,,,HBP,-1.50033,0.0758425,0.000451517,0.984529 beta-lactamase_625_P224H,beta-lactamase_625_224,TEM-1,beta-lactamase_625,P62593,0.984536,NO,224,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.893,-4.649,3.756,,0.383,,B,0.52,-0.3,1.35,,74.48,HOH,-1.26433,0.213352,0.00189564,0.984536 beta-lactamase_0_S80H,beta-lactamase_0_80,TEM-1,beta-lactamase_0,P62593,0.984537,NO,80,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.029,-3.359,1.33,,0.192,H,A,0.27,0.46,12.403,12.403,77.62,HPB,-1.44567,0.0500837,0.00565569,0.984537 beta-lactamase_625_L160V,beta-lactamase_625_160,TEM-1,beta-lactamase_625,P62593,0.984537,NO,160,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.977,-2.271,1.294,,0.022,,B,0.55,-0.6,0.237,,44.41,BHA,-0.936,0.213352,0.00193775,0.984537 kka2_1:4_A255L,kka2_1:4_255,Kka2,kka2_1:4,P00552,0.984545,NO,255,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.715,-3.015,1.3,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.168804,0.0126809,0.984545 beta-lactamase_2500_E108K,beta-lactamase_2500_108,TEM-1,beta-lactamase_2500,P62593,0.984555,NO,108,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.46,-2.182,0.722,,0.572,G,A,1.04,1.87,1.147,,72.73,PAB,-1.437,0.361275,0.00413372,0.984555 beta-lactamase_2500_I206V,beta-lactamase_2500_206,TEM-1,beta-lactamase_2500,P62593,0.984555,NO,206,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-2.429,-2.433,0.004,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.361275,0.00528934,0.984555 beta-lactamase_I45I,beta-lactamase_45,TEM-1,beta-lactamase,P62593,0.984567,NO,45,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-2.421,-2.421,,5.31505,,E,B,1,-0.3,2.256,,77.62,HHA,-2.30267,0.221079,0.00452842,0.984567 beta-lactamase_N50L,beta-lactamase_50,TEM-1,beta-lactamase,P62593,0.984567,NO,50,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-2.979,-2.892,-0.087,5.51261,0.912,T,A,1.07,1.24,1.581,,77.62,HPP,-2.134,0.221079,0.0047211,0.984567 beta-lactamase_625_Q203S,beta-lactamase_625_203,TEM-1,beta-lactamase_625,P62593,0.984569,NO,203,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.168,-2.824,0.656,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.213352,0.00631514,0.984569 beta-lactamase_156_N98Q,beta-lactamase_156_98,TEM-1,beta-lactamase_156,P62593,0.984575,NO,98,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-2.973,-2.336,-0.637,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.111618,0.00505389,0.984575 beta-lactamase_156_E272V,beta-lactamase_156_272,TEM-1,beta-lactamase_156,P62593,0.984576,NO,272,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.111618,0.00545371,0.984576 beta-lactamase_625_I45Q,beta-lactamase_625_45,TEM-1,beta-lactamase_625,P62593,0.984584,NO,45,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-2.421,-3.24,0.819,,,E,B,0.48,-0.3,3.642,,77.62,HHA,-2.30267,0.213352,0.00452842,0.984584 beta-lactamase_39_R162E,beta-lactamase_39_162,TEM-1,beta-lactamase_39,P62593,0.984585,NO,162,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.016,-3.337,2.321,,0.124,S,B,1.2,-0.37,31.656,31.656,64.69,ABH,-1.25,0.0495842,0.000561334,0.984585 beta-lactamase_39_S51T,beta-lactamase_39_51,TEM-1,beta-lactamase_39,P62593,0.984586,NO,51,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.526,-1.846,0.32,,0.496,T,A,0.27,0.26,2.964,,72.73,PPO,-1.88467,0.0495842,0.00504821,0.984586 beta-lactamase_625_D207V,beta-lactamase_625_207,TEM-1,beta-lactamase_625,P62593,0.984587,NO,207,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.064,-3.771,1.707,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.213352,0.00592942,0.984587 beta-lactamase_39_Q97R,beta-lactamase_39_97,TEM-1,beta-lactamase_39,P62593,0.984589,NO,97,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.072,-2.428,0.356,,0.823,G,A,0.64,2.42,4.457,,77.62,PPP,-2.43833,0.0495842,0.0045116,0.984589 beta-lactamase_39_T269D,beta-lactamase_39_269,TEM-1,beta-lactamase_39,P62593,0.984592,NO,269,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.156,-3.518,1.362,,0.646,H,A,0.53,0.4,3.889,,77.62,HPH,-1.96733,0.0495842,0.00950944,0.984592 beta-lactamase_2500_A77L,beta-lactamase_2500_77,TEM-1,beta-lactamase_2500,P62593,0.984594,NO,77,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.234,-2.423,1.189,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.361275,0.00282362,0.984594 beta-lactamase_625_T264L,beta-lactamase_625_264,TEM-1,beta-lactamase_625,P62593,0.984596,NO,264,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.213352,0.0119399,0.984596 beta-lactamase_625_L111S,beta-lactamase_625_111,TEM-1,beta-lactamase_625,P62593,0.984603,NO,111,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.76,-3.564,1.804,,0.328,T,A,0.55,0.93,2.26,,64.34,BHP,-1.884,0.213352,0.00480671,0.984603 beta-lactamase_A133G,beta-lactamase_133,TEM-1,beta-lactamase,P62593,0.984604,NO,133,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.186,-1.519,0.333,4.86423,,H,A,0.55,-0.86,2.649,,67.83,HHP,-0.988333,0.221079,0.00468022,0.984604 beta-lactamase_625_S51F,beta-lactamase_625_51,TEM-1,beta-lactamase_625,P62593,0.984606,NO,51,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.526,-4.284,2.758,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.213352,0.00504821,0.984606 beta-lactamase_39_T264N,beta-lactamase_39_264,TEM-1,beta-lactamase_39,P62593,0.98461,NO,264,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.0495842,0.0119399,0.98461 kka2_1:4_A65W,kka2_1:4_65,Kka2,kka2_1:4,P00552,0.984613,NO,65,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.744,-5.541,3.797,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.168804,0.00709258,0.984613 beta-lactamase_625_Q276H,beta-lactamase_625_276,TEM-1,beta-lactamase_625,P62593,0.984619,NO,276,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.213352,0.0191712,0.984619 beta-lactamase_156_A84P,beta-lactamase_156_84,TEM-1,beta-lactamase_156,P62593,0.98462,NO,84,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.651,-3.933,2.282,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.111618,0.00503822,0.98462 beta-lactamase_156_S96Y,beta-lactamase_156_96,TEM-1,beta-lactamase_156,P62593,0.98462,NO,96,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.27,-4.345,2.075,,0.368,,b,0.27,0.39,2.838,,73.78,HPP,-2.019,0.111618,0.00551835,0.98462 beta-lactamase_R255K,beta-lactamase_255,TEM-1,beta-lactamase,P62593,0.984627,NO,255,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.266,-3.658,1.392,5.55882,0.141,E,B,0.68,0.38,1.199,,63.99,PBH,-2.00433,0.221079,0.00499612,0.984627 beta-lactamase_S80M,beta-lactamase_80,TEM-1,beta-lactamase,P62593,0.984627,NO,80,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.029,-4.671,2.642,5.23748,0.192,H,A,0.25,0.46,2.256,,77.62,HPB,-1.44567,0.221079,0.00565569,0.984627 beta-lactamase_156_Q276G,beta-lactamase_156_276,TEM-1,beta-lactamase_156,P62593,0.984633,NO,276,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.111618,0.0191712,0.984633 beta-lactamase_2500_E56G,beta-lactamase_2500_56,TEM-1,beta-lactamase_2500,P62593,0.984634,NO,56,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.043,-2.304,0.261,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.361275,0.00238534,0.984634 beta-lactamase_156_T187D,beta-lactamase_156_187,TEM-1,beta-lactamase_156,P62593,0.984637,NO,187,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.401,-2.769,1.368,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.111618,0.00491782,0.984637 beta-lactamase_156_R81E,beta-lactamase_156_81,TEM-1,beta-lactamase_156,P62593,0.984645,NO,81,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.466,-2.677,1.211,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.111618,0.00499763,0.984645 beta-lactamase_625_S283D,beta-lactamase_625_283,TEM-1,beta-lactamase_625,P62593,0.984649,NO,283,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.213352,0.0429138,0.984649 beta-lactamase_2500_V31I,beta-lactamase_2500_31,TEM-1,beta-lactamase_2500,P62593,0.984652,NO,31,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.822,-1.838,0.016,,,H,A,0.44,-0.46,0.955,,73.78,BHB,-2.03767,0.361275,0.00478065,0.984652 beta-lactamase_K144M,beta-lactamase_144,TEM-1,beta-lactamase,P62593,0.984654,NO,144,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-2.388,-4.736,2.348,6.02507,0.863,H,A,2.81,1.27,0.515,,77.62,OBA,-1.904,0.221079,0.00481141,0.984654 Pab1_K164R,Pab1_164,Pab1,Pab1,P04147,0.984654,NO,164,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-2.298,-2.662,0.364,,,,,,,,,,OBP,-1.41767,0.175299,0.00255241,0.984654 beta-lactamase_39_E175W,beta-lactamase_39_175,TEM-1,beta-lactamase_39,P62593,0.98466,NO,175,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.336,-5.537,3.201,,0.551,,A,1.04,1.05,3.676,,77.62,AAB,-1.31233,0.0495842,0.00482205,0.98466 beta-lactamase_2500_T112Q,beta-lactamase_2500_112,TEM-1,beta-lactamase_2500,P62593,0.984664,NO,112,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.186,-3.981,1.795,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.361275,0.00531334,0.984664 beta-lactamase_625_I171V,beta-lactamase_625_171,TEM-1,beta-lactamase_625,P62593,0.984665,NO,171,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-2.431,-3.274,0.843,,0.361,,B,0.48,0.53,3.869,,77.62,HHO,-1.55533,0.213352,0.00623355,0.984665 WW_domain_I193L,WW_domain_193,Yap65,WW_domain,P46937,0.984671,NO,193,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.993,-2.331,0.338,6.15906,,,,,,1.833,,83.33,BHA,-1.756,0.153962,0.00587613,0.984671 beta-lactamase_0_V157S,beta-lactamase_0_157,TEM-1,beta-lactamase_0,P62593,0.984672,NO,157,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.751,-2.878,1.127,,0.308,S,a,0.44,-0.75,3.106,,69.58,BHP,-2.00767,0.0500837,0.00506849,0.984672 beta-lactamase_2500_R92V,beta-lactamase_2500_92,TEM-1,beta-lactamase_2500,P62593,0.984677,NO,92,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.718,-2.509,0.791,,0.479,E,B,1.2,1.36,3.069,,65.38,BBH,-1.50367,0.361275,0.00429626,0.984677 PSD95pdz3_K380H,PSD95pdz3_380,PSD95pdz3,PSD95pdz3,P31016,0.984686,NO,380,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.416,-4.137,2.721,5.87979,,,,,19.6722,,,,HBP,-1.391,0.0758425,0.000281399,0.984686 beta-lactamase_156_L73T,beta-lactamase_156_73,TEM-1,beta-lactamase_156,P62593,0.984689,NO,73,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.507,-3.582,2.075,,,H,A,0.55,-0.64,2.09,,67.83,HHH,-1.487,0.111618,0.00488983,0.984689 Pab1_I183H,Pab1_183,Pab1,Pab1,P04147,0.98469,NO,183,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.302,-4.775,3.473,,0.308,T,B,1,1.08,1.29,,75.56,HHA,-1.27167,0.175299,0.000574345,0.98469 beta-lactamase_2500_G39A,beta-lactamase_2500_39,TEM-1,beta-lactamase_2500,P62593,0.984692,NO,39,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.864,-2.728,0.864,,0.701,T,L,0.29,0.47,29.926,29.926,77.62,HOH,-1.53633,0.361275,0.00487611,0.984692 beta-lactamase_625_V72A,beta-lactamase_625_72,TEM-1,beta-lactamase_625,P62593,0.984693,NO,72,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.658,-1.729,0.071,,,H,A,0.44,-1.03,0.981,,65.73,BHH,-1.32167,0.213352,0.00501194,0.984693 beta-lactamase_2500_E145Q,beta-lactamase_2500_145,TEM-1,beta-lactamase_2500,P62593,0.984694,NO,145,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.357,-2.979,0.622,,0.545,H,A,1.04,0.79,2.124,,77.62,BAH,-2.069,0.361275,0.00553285,0.984694 beta-lactamase_156_D231R,beta-lactamase_156_231,TEM-1,beta-lactamase_156,P62593,0.984698,NO,231,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.816,-3.896,3.08,,,E,B,0.75,-1.06,2.66,,65.38,HAB,-0.994,0.111618,0.00107395,0.984698 beta-lactamase_2500_A183M,beta-lactamase_2500_183,TEM-1,beta-lactamase_2500,P62593,0.9847,NO,183,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.231,-4.59,3.359,,0.155,H,A,0.46,-0.91,12.189,,77.62,HHH,-1.53367,0.361275,0.00296631,0.9847 kka2_1:2_E231R,kka2_1:2_231,Kka2,kka2_1:2,P00552,0.984702,NO,231,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.002,-3.767,1.765,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.295029,0.00732383,0.984702 beta-lactamase_2500_G85H,beta-lactamase_2500_85,TEM-1,beta-lactamase_2500,P62593,0.984705,NO,85,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.011,-4.646,3.635,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.361275,0.00252173,0.984705 beta-lactamase_625_K286T,beta-lactamase_625_286,TEM-1,beta-lactamase_625,P62593,0.984708,NO,286,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.213352,,0.984708 beta-lactamase_156_P143F,beta-lactamase_156_143,TEM-1,beta-lactamase_156,P62593,0.984709,NO,143,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.967,-4.308,3.341,,0.075,H,A,0.52,-0.37,0.479,,66.78,OOB,-1.354,0.111618,0.00114551,0.984709 beta-lactamase_156_A148I,beta-lactamase_156_148,TEM-1,beta-lactamase_156,P62593,0.984721,NO,148,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.757,-4.049,2.292,,0.379,H,A,0.46,-0.55,3.551,,72.73,PHH,-1.40167,0.111618,0.00547053,0.984721 beta-lactamase_156_E169S,beta-lactamase_156_169,TEM-1,beta-lactamase_156,P62593,0.984723,NO,169,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.23,-2.21,0.98,,0.337,,A,1.04,1,3.516,,73.08,PAH,-1.16533,0.111618,0.00400994,0.984723 beta-lactamase_2500_R81K,beta-lactamase_2500_81,TEM-1,beta-lactamase_2500,P62593,0.984724,NO,81,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.466,-2.393,0.927,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.361275,0.00499763,0.984724 beta-lactamase_A9K,beta-lactamase_9,TEM-1,beta-lactamase,P62593,0.984728,NO,9,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.147,-3.679,1.532,,,,,,,5.128,,72.73,HHH,-2.04267,0.221079,0.00247263,0.984728 beta-lactamase_F17T,beta-lactamase_17,TEM-1,beta-lactamase,P62593,0.984728,NO,17,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-2.337,-3.44,1.103,,,,,,,2.192,,67.83,HHO,-2.17733,0.221079,0.00216499,0.984728 beta-lactamase_I45A,beta-lactamase_45,TEM-1,beta-lactamase,P62593,0.984728,NO,45,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-2.421,-2.001,-0.42,5.31505,,E,B,1,-0.3,2.256,,77.62,HHA,-2.30267,0.221079,0.00452842,0.984728 beta-lactamase_K32S,beta-lactamase_32,TEM-1,beta-lactamase,P62593,0.984728,NO,32,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.984,-3.371,1.387,5.55842,0.563,H,A,1.82,0.34,1.754,,73.08,HBA,-2.04233,0.221079,0.00401283,0.984728 beta-lactamase_N98V,beta-lactamase_98,TEM-1,beta-lactamase,P62593,0.984728,NO,98,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-2.973,-3.696,0.723,6.59973,0.963,G,A,1.07,1.35,1.332,,77.62,PPA,-2.07867,0.221079,0.00505389,0.984728 beta-lactamase_Q265Y,beta-lactamase_265,TEM-1,beta-lactamase,P62593,0.984728,NO,265,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.58,-4.379,1.799,6.62674,1.116,,A,0.03,1.17,12.514,12.514,69.58,PPH,-1.978,0.221079,0.00811926,0.984728 beta-lactamase_S80S,beta-lactamase_80,TEM-1,beta-lactamase,P62593,0.984728,NO,80,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.029,-2.029,,5.23748,0.192,H,A,0.25,0.46,2.256,,77.62,HPB,-1.44567,0.221079,0.00565569,0.984728 PSD95pdz3_K355D,PSD95pdz3_355,PSD95pdz3,PSD95pdz3,P31016,0.984732,NO,355,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.416,-3.15,1.734,5.56865,,,,,17.2556,,,,BBO,-1.33533,0.0758425,0.00063703,0.984732 beta-lactamase_39_P105F,beta-lactamase_39_105,TEM-1,beta-lactamase_39,P62593,0.984738,NO,105,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.813,-4.48,3.667,,0.226,T,A,0.52,0.8,1.222,,63.29,POH,-1.01533,0.0495842,0.0011981,0.984738 beta-lactamase_39_L188G,beta-lactamase_39_188,TEM-1,beta-lactamase_39,P62593,0.984739,NO,188,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.166,-3.699,2.533,,,H,A,0.55,-0.3,2.982,,60.14,PHB,-1.47033,0.0495842,0.00295687,0.984739 hsp90_E590T,hsp90_590,hsp90,hsp90,P02829,0.984739,NO,590,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.818,-2.8,0,4.65049,0.021,H,A,,0.03,,,,HAO,-3.338,0.368192,0.000222939,0.984739 beta-lactamase_2500_K254N,beta-lactamase_2500_254,TEM-1,beta-lactamase_2500,P62593,0.984741,NO,254,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.361275,0.00369,0.984741 beta-lactamase_39_I261T,beta-lactamase_39_261,TEM-1,beta-lactamase_39,P62593,0.984741,NO,261,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-2.88,-1.929,-0.951,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.0495842,0.0123091,0.984741 beta-lactamase_156_G90S,beta-lactamase_156_90,TEM-1,beta-lactamase_156,P62593,0.984746,NO,90,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-2.091,-2.198,0.107,,0.598,T,A,0.29,0.32,0.319,,77.62,HOB,-1.52633,0.111618,0.00490273,0.984746 beta-lactamase_156_G253P,beta-lactamase_156_253,TEM-1,beta-lactamase_156,P62593,0.984755,NO,253,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-2.253,-2.791,0.538,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.111618,0.00786358,0.984755 beta-lactamase_156_G216V,beta-lactamase_156_216,TEM-1,beta-lactamase_156,P62593,0.984757,NO,216,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.477,-3.793,2.316,,0.437,I,A,0.29,-0.58,12.464,12.464,74.48,HOO,-1.68067,0.111618,0.00639568,0.984757 beta-lactamase_2500_T131G,beta-lactamase_2500_131,TEM-1,beta-lactamase_2500,P62593,0.984757,NO,131,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.328,-3.298,1.97,,,H,A,0.22,-0.69,3.048,,67.48,PPH,-1.00867,0.361275,0.00345886,0.984757 beta-lactamase_156_T126Y,beta-lactamase_156_126,TEM-1,beta-lactamase_156,P62593,0.98476,NO,126,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.122,-4.294,3.172,,0.05,H,A,0.22,-0.05,1.14,,44.41,HPH,-1.60467,0.111618,0.00244552,0.98476 Pab1_N162Q,Pab1_162,Pab1,Pab1,P04147,0.984763,NO,162,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-2.313,-2.902,0.589,,0.681,T,A,,1.12,,,,APO,-1.532,0.175299,0.0030719,0.984763 beta-lactamase_39_V29N,beta-lactamase_39_29,TEM-1,beta-lactamase_39,P62593,0.98477,NO,29,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-2.856,-2.832,-0.024,,0.733,H,A,0.44,-0.78,1.287,,93.01,HHB,-2.24733,0.0495842,0.00318969,0.98477 beta-lactamase_625_G154S,beta-lactamase_625_154,TEM-1,beta-lactamase_625,P62593,0.98477,NO,154,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.823,-3.197,2.374,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.213352,0.00180205,0.98477 beta-lactamase_625_I206G,beta-lactamase_625_206,TEM-1,beta-lactamase_625,P62593,0.984772,NO,206,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-2.429,-2.667,0.238,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.213352,0.00528934,0.984772 beta-lactamase_39_L218H,beta-lactamase_39_218,TEM-1,beta-lactamase_39,P62593,0.984774,NO,218,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.391,-4.744,3.353,,,I,b,0.55,-0.53,2.038,,74.48,OHH,-1.58867,0.0495842,0.00618274,0.984774 beta-lactamase_625_P172Y,beta-lactamase_625_172,TEM-1,beta-lactamase_625,P62593,0.984777,NO,172,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.998,-4.368,3.37,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.213352,0.00312594,0.984777 beta-lactamase_39_N98Q,beta-lactamase_39_98,TEM-1,beta-lactamase_39,P62593,0.984779,NO,98,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-2.973,-2.336,-0.637,,0.963,G,A,0.61,1.35,14.853,14.853,77.62,PPA,-2.07867,0.0495842,0.00505389,0.984779 kka2_1:1_E160E,kka2_1:1_160,Kka2,kka2_1:1,P00552,0.98478,NO,160,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.683,-1.683,,,0.989,G,A,1.04,2.28,0.273,,71.59,AAA,-1.36133,0.520039,0.00935762,0.98478 beta-lactamase_156_N168R,beta-lactamase_156_168,TEM-1,beta-lactamase_156,P62593,0.984784,NO,168,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-1.029,-3.58,2.551,,0.113,G,A,0.61,-0.4,1.014,,44.41,HPA,-1.13233,0.111618,0.00288667,0.984784 beta-lactamase_625_G90L,beta-lactamase_625_90,TEM-1,beta-lactamase_625,P62593,0.984784,NO,90,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-2.091,-3.689,1.598,,0.598,T,A,0.29,0.32,0.319,,77.62,HOB,-1.52633,0.213352,0.00490273,0.984784 Pab1_F149W,Pab1_149,Pab1,Pab1,P04147,0.984785,NO,149,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.149,-4.24,3.091,,0.183,T,A,1.33,1.09,,,,HHO,-1.27767,0.175299,0.000325688,0.984785 beta-lactamase_156_L28F,beta-lactamase_156_28,TEM-1,beta-lactamase_156,P62593,0.984789,NO,28,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.579,-3.916,2.337,,0.277,H,A,0.55,-0.16,3.262,,93.01,PHH,-2.11333,0.111618,0.00359321,0.984789 beta-lactamase_156_Q276L,beta-lactamase_156_276,TEM-1,beta-lactamase_156,P62593,0.984789,NO,276,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.111618,0.0191712,0.984789 hsp90_Q582C,hsp90_582,hsp90,hsp90,P02829,0.984792,NO,582,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-3.278,-4.015,0,4.91603,0.453,S,B,,0.67,,,,OPH,-3.249,0.368192,0.000222939,0.984792 beta-lactamase_2500_D207T,beta-lactamase_2500_207,TEM-1,beta-lactamase_2500,P62593,0.984793,NO,207,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.064,-2.565,0.501,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.361275,0.00592942,0.984793 PSD95pdz3_V386G,PSD95pdz3_386,PSD95pdz3,PSD95pdz3,P31016,0.984794,NO,386,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.465,-3.265,1.8,5.18836,,,,,17.5429,,,,PHP,-1.463,0.0758425,0.000184509,0.984794 beta-lactamase_0_V259F,beta-lactamase_0_259,TEM-1,beta-lactamase_0,P62593,0.984798,NO,259,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.0500837,0.0070773,0.984798 beta-lactamase_156_G265A,beta-lactamase_156_265,TEM-1,beta-lactamase_156,P62593,0.984801,NO,265,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.111618,0.00811926,0.984801 beta-lactamase_156_A40H,beta-lactamase_156_40,TEM-1,beta-lactamase_156,P62593,0.984804,NO,40,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.402,-4.792,3.39,,0.155,S,B,0.46,0.21,1.357,,73.78,OHB,-1.40267,0.111618,0.00490026,0.984804 beta-lactamase_156_K254M,beta-lactamase_156_254,TEM-1,beta-lactamase_156,P62593,0.984809,NO,254,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.111618,0.00369,0.984809 beta-lactamase_625_F228W,beta-lactamase_625_228,TEM-1,beta-lactamase_625,P62593,0.984809,NO,228,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-2.342,-5.275,2.933,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.213352,0.0046669,0.984809 beta-lactamase_625_S256W,beta-lactamase_625_256,TEM-1,beta-lactamase_625,P62593,0.984816,NO,256,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.213352,0.00710634,0.984816 beta-lactamase_39_L284T,beta-lactamase_39_284,TEM-1,beta-lactamase_39,P62593,0.984817,NO,284,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.0495842,0.0686156,0.984817 Pab1_E195Y,Pab1_195,Pab1,Pab1,P04147,0.984818,NO,195,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.2,-3.973,2.773,,,,,,,,,,PAH,-1.72467,0.175299,0.000620107,0.984818 beta-lactamase_156_L199R,beta-lactamase_156_199,TEM-1,beta-lactamase_156,P62593,0.984819,NO,199,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-2.942,-3.181,0.239,,0.832,H,A,0.55,0.42,1.552,,77.62,PHH,-2.32933,0.111618,0.0048649,0.984819 beta-lactamase_625_S96Y,beta-lactamase_625_96,TEM-1,beta-lactamase_625,P62593,0.98482,NO,96,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.27,-4.345,2.075,,0.368,,b,0.27,0.39,5.244,,73.78,HPP,-2.019,0.213352,0.00551835,0.98482 beta-lactamase_156_A211Q,beta-lactamase_156_211,TEM-1,beta-lactamase_156,P62593,0.984823,NO,211,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.896,-3.096,1.2,,0.369,T,A,0.46,-0.69,8.527,8.527,77.62,AHA,-1.94633,0.111618,0.00648183,0.984823 gb1_N234I,gb1_234,gb1,gb1,P06654,0.984824,NO,234,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-2.055,-3.85,1.795,,,,,,,1.235,,45.54,HPO,-2.05067,0.177985,0.00242189,0.984824 beta-lactamase_39_L146M,beta-lactamase_39_146,TEM-1,beta-lactamase_39,P62593,0.984829,NO,146,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.462,-4.183,2.721,,0.007,H,A,0.55,-0.56,1.953,,64.69,AHP,-1.656,0.0495842,0.00474542,0.984829 beta-lactamase_39_P65N,beta-lactamase_39_65,TEM-1,beta-lactamase_39,P62593,0.984831,NO,65,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.894,-3.952,3.058,,0.098,E,B,0.52,-0.62,0.623,,40.56,HOH,-1.03233,0.0495842,0.00152776,0.984831 beta-lactamase_39_Y44C,beta-lactamase_39_44,TEM-1,beta-lactamase_39,P62593,0.984832,NO,44,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-2.547,-4.829,2.282,,,E,B,0.21,-0.45,2.683,,73.78,OHH,-1.86267,0.0495842,0.00426364,0.984832 beta-lactamase_625_P143V,beta-lactamase_625_143,TEM-1,beta-lactamase_625,P62593,0.98484,NO,143,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.967,-3.311,2.344,,0.075,H,A,0.52,-0.37,1.445,,66.78,OOB,-1.354,0.213352,0.00114551,0.98484 beta-lactamase_625_T264H,beta-lactamase_625_264,TEM-1,beta-lactamase_625,P62593,0.98484,NO,264,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.213352,0.0119399,0.98484 beta-lactamase_156_L38P,beta-lactamase_156_38,TEM-1,beta-lactamase_156,P62593,0.984842,NO,38,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.343,-2.934,1.591,,0.088,H,A,0.55,0.2,13.556,13.556,64.34,PHO,-1.78033,0.111618,0.00373244,0.984842 beta-lactamase_I275V,beta-lactamase_275,TEM-1,beta-lactamase,P62593,0.984845,NO,275,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.397,-2.069,0.672,5.3999,0.015,H,A,1,-0.52,0.836,,62.59,PHH,-1.541,0.221079,0.0141984,0.984845 beta-lactamase_2500_D252T,beta-lactamase_2500_252,TEM-1,beta-lactamase_2500,P62593,0.984847,NO,252,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.94,,,,0.766,,B,1.59,1.16,,,67.83,OAO,-2.0965,0.361275,0.00575769,0.984847 beta-lactamase_625_G253E,beta-lactamase_625_253,TEM-1,beta-lactamase_625,P62593,0.984848,NO,253,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.213352,0.00786358,0.984848 Pab1_N162N,Pab1_162,Pab1,Pab1,P04147,0.984848,NO,162,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-2.313,-2.313,,,0.681,T,A,,1.12,,,,APO,-1.532,0.175299,0.0030719,0.984848 beta-lactamase_39_P105C,beta-lactamase_39_105,TEM-1,beta-lactamase_39,P62593,0.984851,NO,105,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.813,-5.05,4.237,,0.226,T,A,0.52,0.8,1.222,,63.29,POH,-1.01533,0.0495842,0.0011981,0.984851 beta-lactamase_39_A123M,beta-lactamase_39_123,TEM-1,beta-lactamase_39,P62593,0.984854,NO,123,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.834,-4.443,3.609,,0.039,H,A,0.46,-0.72,0.705,,41.26,PHH,-1.47367,0.0495842,0.0010157,0.984854 kka2_1:8_G99H,kka2_1:8_99,Kka2,kka2_1:8,P00552,0.984854,NO,99,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.596,-4.708,4.112,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.100394,0.00186055,0.984854 kka2_1:8_G99H,kka2_1:8_99,Kka2,kka2_1:8,P00552,0.984854,NO,99,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.596,-4.708,4.112,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.100394,0.00186055,0.984854 beta-lactamase_2500_K254F,beta-lactamase_2500_254,TEM-1,beta-lactamase_2500,P62593,0.984865,NO,254,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.361275,0.00369,0.984865 beta-lactamase_39_A170N,beta-lactamase_39_170,TEM-1,beta-lactamase_39,P62593,0.984881,NO,170,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.237,-2.833,1.596,,0.126,,L,0.46,-0.35,3.7,,64.69,AHH,-1.63267,0.0495842,0.00431903,0.984881 beta-lactamase_156_R239W,beta-lactamase_156_239,TEM-1,beta-lactamase_156,P62593,0.984888,NO,239,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.111618,0.00213852,0.984888 Pab1_I183T,Pab1_183,Pab1,Pab1,P04147,0.984889,NO,183,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.302,-3.232,1.93,,0.308,T,B,1,1.08,1.29,,75.56,HHA,-1.27167,0.175299,0.000574345,0.984889 Pab1_A178G,Pab1_178,Pab1,Pab1,P04147,0.984892,NO,178,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.579,-3.018,1.439,,0.019,H,A,0.64,0.64,2.7,,81.63,OHH,-1.61067,0.175299,0.00160192,0.984892 beta-lactamase_625_R239M,beta-lactamase_625_239,TEM-1,beta-lactamase_625,P62593,0.984895,NO,239,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.213352,0.00213852,0.984895 Pab1_E174V,Pab1_174,Pab1,Pab1,P04147,0.984906,NO,174,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.422,-3.546,2.124,,0.578,S,A,,0.38,,,,HAA,-1.65133,0.175299,0.00077863,0.984906 beta-lactamase_2500_H156R,beta-lactamase_2500_156,TEM-1,beta-lactamase_2500,P62593,0.984907,NO,156,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-3.156,-2.742,-0.414,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.361275,0.00468596,0.984907 beta-lactamase_2500_K109H,beta-lactamase_2500_109,TEM-1,beta-lactamase_2500,P62593,0.984907,NO,109,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.734,-3.369,1.635,,0.787,G,A,2.34,2.21,0.998,,72.73,ABB,-1.63333,0.361275,0.00462493,0.984907 beta-lactamase_156_G194M,beta-lactamase_156_194,TEM-1,beta-lactamase_156,P62593,0.984914,NO,194,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.396,-4.893,3.497,,0.276,S,b,0.29,0.36,1.346,,67.83,POA,-1.832,0.111618,0.00392163,0.984914 beta-lactamase_2500_V157T,beta-lactamase_2500_157,TEM-1,beta-lactamase_2500,P62593,0.984923,NO,157,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.751,-2.302,0.551,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.361275,0.00506849,0.984923 beta-lactamase_39_G236Q,beta-lactamase_39_236,TEM-1,beta-lactamase_39,P62593,0.984925,NO,236,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.784,-4.093,3.309,,0.241,,b,0.29,-0.59,1.883,,64.69,HOO,-1.025,0.0495842,0.00162372,0.984925 beta-lactamase_625_R91H,beta-lactamase_625_91,TEM-1,beta-lactamase_625,P62593,0.984931,NO,91,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.392,-4.422,3.03,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.213352,0.00380226,0.984931 beta-lactamase_625_V214A,beta-lactamase_625_214,TEM-1,beta-lactamase_625,P62593,0.984937,NO,214,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.299,-2.434,1.135,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.213352,0.00628442,0.984937 beta-lactamase_39_E210S,beta-lactamase_39_210,TEM-1,beta-lactamase_39,P62593,0.98494,NO,210,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.319,-2.669,0.35,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.0495842,0.00663582,0.98494 beta-lactamase_0_K32V,beta-lactamase_0_32,TEM-1,beta-lactamase_0,P62593,0.984951,NO,32,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.984,-3.477,1.493,,0.563,H,A,2.34,0.34,0.418,,73.08,HBA,-2.04233,0.0500837,0.00401283,0.984951 beta-lactamase_2500_Q97I,beta-lactamase_2500_97,TEM-1,beta-lactamase_2500,P62593,0.984953,NO,97,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.072,-4.072,2,,0.823,G,A,0.64,2.42,1.157,,77.62,PPP,-2.43833,0.361275,0.0045116,0.984953 beta-lactamase_2500_N50I,beta-lactamase_2500_50,TEM-1,beta-lactamase_2500,P62593,0.984954,NO,50,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-2.979,-3.889,0.91,,0.912,T,A,0.61,1.24,1.581,,77.62,HPP,-2.134,0.361275,0.0047211,0.984954 kka2_1:2_R239V,kka2_1:2_239,Kka2,kka2_1:2,P00552,0.984957,NO,239,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.949,-2.967,0.018,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.295029,0.00835326,0.984957 beta-lactamase_39_K32C,beta-lactamase_39_32,TEM-1,beta-lactamase_39,P62593,0.984967,NO,32,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.984,-5.093,3.109,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.0495842,0.00401283,0.984967 E1_Ubiquitin_A46R,E1_Ubiquitin_46,Uba1,E1_Ubiquitin,P0CG63,0.984969,NO,46,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.367,-3.725,2.358,,0.398,T,L,,-0.8,,,,HHO,-1.17167,0.18783,0.004233,0.984969 E1_Ubiquitin_A46W,E1_Ubiquitin_46,Uba1,E1_Ubiquitin,P0CG63,0.984969,NO,46,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.367,-5.192,3.825,,0.398,T,L,,-0.8,,,,HHO,-1.17167,0.18783,0.004233,0.984969 E1_Ubiquitin_K48M,E1_Ubiquitin_48,Uba1,E1_Ubiquitin,P0CG63,0.984969,NO,48,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.219,-4.401,3.182,,0.132,E,B,,-0.28,,,,OBO,-1.109,0.18783,0.00100363,0.984969 E1_Ubiquitin_L71Q,E1_Ubiquitin_71,Uba1,E1_Ubiquitin,P0CG63,0.984969,NO,71,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.039,-3.941,2.902,,0.591,E,B,,-0.69,,,,BHB,-1.19433,0.18783,0.00148349,0.984969 E1_Ubiquitin_Q40W,E1_Ubiquitin_40,Uba1,E1_Ubiquitin,P0CG63,0.984969,NO,40,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-1.48,-5.051,3.571,,0.387,G,A,,0.03,,,,OPP,-1.365,0.18783,0.0037961,0.984969 E1_Ubiquitin_R74P,E1_Ubiquitin_74,Uba1,E1_Ubiquitin,P0CG63,0.984969,NO,74,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.302,-3.69,2.388,,0.838,T,A,,3.15,,,,HBO,-1.11333,0.18783,0.00180798,0.984969 beta-lactamase_156_L89D,beta-lactamase_156_89,TEM-1,beta-lactamase_156,P62593,0.984972,NO,89,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.096,-3.996,2.9,,0.168,T,A,0.55,0.63,2.633,,64.34,PHO,-1.75767,0.111618,0.00207068,0.984972 beta-lactamase_156_R176Q,beta-lactamase_156_176,TEM-1,beta-lactamase_156,P62593,0.984986,NO,176,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-0.863,-3.449,2.586,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.111618,0.00105554,0.984986 beta-lactamase_39_T269I,beta-lactamase_39_269,TEM-1,beta-lactamase_39,P62593,0.984993,NO,269,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.156,,,,0.646,H,A,0.53,0.4,3.889,,77.62,HPH,-1.96733,0.0495842,0.00950944,0.984993 Pab1_A199H,Pab1_199,Pab1,Pab1,P04147,0.984998,NO,199,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.53,-4.568,3.038,,,,,,,1.479,,80.42,HHO,-1.50467,0.175299,0.00145024,0.984998 beta-lactamase_156_R220A,beta-lactamase_156_220,TEM-1,beta-lactamase_156,P62593,0.985,NO,220,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-0.942,-2.357,1.415,,0.295,I,A,1.2,-0.76,2.164,,74.48,HBP,-1.33633,0.111618,0.00232421,0.985 gb1_Q228D,gb1_228,gb1,gb1,P06654,0.985001,NO,228,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,,,,,,,,,,,,,OPH,-1.282,0.177985,0.00391043,0.985001 beta-lactamase_P60V,beta-lactamase_60,TEM-1,beta-lactamase,P62593,0.985003,NO,60,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-2.469,-3.507,1.038,5.51353,0.256,T,A,0.73,-0.56,3.653,,77.62,BOA,-1.97633,0.221079,0.00521318,0.985003 kka2_1:2_D180Y,kka2_1:2_180,Kka2,kka2_1:2,P00552,0.985004,NO,180,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.416,-3.544,1.128,,1.03,S,a,0.75,1.5,1.27,,71.59,OAO,-2.02933,0.295029,0.00756412,0.985004 beta-lactamase_2500_N98L,beta-lactamase_2500_98,TEM-1,beta-lactamase_2500,P62593,0.985007,NO,98,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-2.973,-3.59,0.617,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.361275,0.00505389,0.985007 beta-lactamase_0_C121S,beta-lactamase_0_121,TEM-1,beta-lactamase_0,P62593,0.98501,NO,121,C,S,CS,Special,Polar,5.07,5.68,0.61,112,121,105,-16,108.5,89,-19.5,-0.953,-3.411,2.458,,,H,A,0.46,-0.81,3.302,,63.29,HOP,-1.46767,0.0500837,0.000744322,0.98501 beta-lactamase_156_R81A,beta-lactamase_156_81,TEM-1,beta-lactamase_156,P62593,0.98501,NO,81,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.466,-2.609,1.143,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.111618,0.00499763,0.98501 kka2_1:2_L103M,kka2_1:2_103,Kka2,kka2_1:2,P00552,0.985017,NO,103,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-2.362,-4.518,2.156,,0.394,T,A,0.55,-0.99,3.499,,63.64,HHP,-1.534,0.295029,0.00574792,0.985017 beta-lactamase_625_L38F,beta-lactamase_625_38,TEM-1,beta-lactamase_625,P62593,0.985025,NO,38,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.343,-3.81,2.467,,0.088,H,A,0.55,0.2,1.986,,64.34,PHO,-1.78033,0.213352,0.00373244,0.985025 kka2_1:8_A237L,kka2_1:8_237,Kka2,kka2_1:8,P00552,0.985026,NO,237,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.12,-2.076,-0.044,,0.068,H,A,0.46,-0.71,0.449,,92.05,HHA,-2.10433,0.100394,0.012257,0.985026 kka2_1:8_A237L,kka2_1:8_237,Kka2,kka2_1:8,P00552,0.985026,NO,237,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.12,-2.076,-0.044,,0.068,H,A,0.46,-0.71,0.449,,92.05,HHA,-2.10433,0.100394,0.012257,0.985026 beta-lactamase_0_A182F,beta-lactamase_0_182,TEM-1,beta-lactamase_0,P62593,0.985028,NO,182,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.777,-4.357,2.58,,0.136,H,A,0.46,-0.66,10.765,10.765,93.01,OHH,-1.27367,0.0500837,0.00559099,0.985028 beta-lactamase_39_A133S,beta-lactamase_39_133,TEM-1,beta-lactamase_39,P62593,0.985029,NO,133,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.186,-3.092,1.906,,,H,A,0.46,-0.86,0.373,,67.83,HHP,-0.988333,0.0495842,0.00468022,0.985029 beta-lactamase_156_R176F,beta-lactamase_156_176,TEM-1,beta-lactamase_156,P62593,0.98503,NO,176,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-0.863,-4.292,3.429,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.111618,0.00105554,0.98503 beta-lactamase_2500_H94F,beta-lactamase_2500_94,TEM-1,beta-lactamase_2500,P62593,0.985039,NO,94,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-2.5,-4.323,1.823,,0.776,,B,0.17,1.24,1.176,,77.62,HBH,-1.872,0.361275,0.00389226,0.985039 beta-lactamase_156_L47C,beta-lactamase_156_47,TEM-1,beta-lactamase_156,P62593,0.985043,NO,47,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.876,-5.002,3.126,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.111618,0.00439844,0.985043 beta-lactamase_156_N98T,beta-lactamase_156_98,TEM-1,beta-lactamase_156,P62593,0.985045,NO,98,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-2.973,-2.907,-0.066,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.111618,0.00505389,0.985045 beta-lactamase_2500_A185G,beta-lactamase_2500_185,TEM-1,beta-lactamase_2500,P62593,0.985047,NO,185,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.406,-3.37,1.964,,,H,A,0.46,-1.02,2.999,,65.03,HHP,-1.84033,0.361275,0.00467449,0.985047 Pab1_G177N,Pab1_177,Pab1,Pab1,P04147,0.985047,NO,177,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-2.24,-2.472,0.232,,,,,,,,,,AOH,-1.94067,0.175299,0.00170727,0.985047 Pab1_A158A,Pab1_158,Pab1,Pab1,P04147,0.985066,NO,158,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.154,-1.154,,,,,,,,1.197,,56.33,HHP,-1.40733,0.175299,0.000649733,0.985066 beta-lactamase_39_S266D,beta-lactamase_39_266,TEM-1,beta-lactamase_39,P62593,0.985067,NO,266,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.0495842,0.0140785,0.985067 beta-lactamase_156_V117M,beta-lactamase_156_117,TEM-1,beta-lactamase_156,P62593,0.985073,NO,117,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.53,-3.063,1.533,,,H,A,0.44,-0.34,1.182,,65.03,PHB,-1.741,0.111618,0.00467906,0.985073 beta-lactamase_156_R189I,beta-lactamase_156_189,TEM-1,beta-lactamase_156,P62593,0.985074,NO,189,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.844,-4.147,2.303,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.111618,0.0050699,0.985074 kka2_1:2_T146W,kka2_1:2_146,Kka2,kka2_1:2,P00552,0.985077,NO,146,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.978,-5.546,2.568,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.295029,0.00606474,0.985077 beta-lactamase_156_E175I,beta-lactamase_156_175,TEM-1,beta-lactamase_156,P62593,0.985078,NO,175,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.336,-3.797,1.461,,0.551,,A,1.04,1.05,2.334,,77.62,AAB,-1.31233,0.111618,0.00482205,0.985078 beta-lactamase_39_L223H,beta-lactamase_39_223,TEM-1,beta-lactamase_39,P62593,0.985089,NO,223,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.055,-4.894,3.839,,0.27,,B,0.55,0.09,1.511,,74.48,HHO,-1.35033,0.0495842,0.00372793,0.985089 beta-lactamase_156_T198D,beta-lactamase_156_198,TEM-1,beta-lactamase_156,P62593,0.98509,NO,198,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.168,-3.544,1.376,,0.489,,B,0.22,-0.13,10.771,10.771,73.78,HPH,-1.98767,0.111618,0.004311,0.98509 beta-lactamase_156_V29I,beta-lactamase_156_29,TEM-1,beta-lactamase_156,P62593,0.985099,NO,29,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-2.856,-3.928,1.072,,0.733,H,A,0.44,-0.78,3.685,,93.01,HHB,-2.24733,0.111618,0.00318969,0.985099 beta-lactamase_625_D33I,beta-lactamase_625_33,TEM-1,beta-lactamase_625,P62593,0.985102,NO,33,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.321,-3.065,0.744,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.213352,0.00435556,0.985102 beta-lactamase_625_P250Q,beta-lactamase_625_250,TEM-1,beta-lactamase_625,P62593,0.985102,NO,250,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.213352,0.00550899,0.985102 beta-lactamase_39_P250W,beta-lactamase_39_250,TEM-1,beta-lactamase_39,P62593,0.985105,NO,250,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.0495842,0.00550899,0.985105 beta-lactamase_625_D33L,beta-lactamase_625_33,TEM-1,beta-lactamase_625,P62593,0.985108,NO,33,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.321,-2.326,0.005,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.213352,0.00435556,0.985108 beta-lactamase_625_D252H,beta-lactamase_625_252,TEM-1,beta-lactamase_625,P62593,0.985117,NO,252,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.213352,0.00575769,0.985117 beta-lactamase_2500_E175A,beta-lactamase_2500_175,TEM-1,beta-lactamase_2500,P62593,0.98512,NO,175,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.336,-2.1,-0.236,,0.551,,A,1.04,1.05,5.316,,77.62,AAB,-1.31233,0.361275,0.00482205,0.98512 beta-lactamase_39_E119R,beta-lactamase_39_119,TEM-1,beta-lactamase_39,P62593,0.985127,NO,119,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.412,-3.743,2.331,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.0495842,0.00386966,0.985127 beta-lactamase_156_D252R,beta-lactamase_156_252,TEM-1,beta-lactamase_156,P62593,0.985129,NO,252,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.111618,0.00575769,0.985129 beta-lactamase_625_Q276I,beta-lactamase_625_276,TEM-1,beta-lactamase_625,P62593,0.985132,NO,276,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.213352,0.0191712,0.985132 beta-lactamase_625_G253N,beta-lactamase_625_253,TEM-1,beta-lactamase_625,P62593,0.985135,NO,253,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.213352,0.00786358,0.985135 beta-lactamase_625_D207K,beta-lactamase_625_207,TEM-1,beta-lactamase_625,P62593,0.985137,NO,207,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.064,-2.897,0.833,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.213352,0.00592942,0.985137 beta-lactamase_39_E35T,beta-lactamase_39_35,TEM-1,beta-lactamase_39,P62593,0.985138,NO,35,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-0.869,-3.447,2.578,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.0495842,0.00174441,0.985138 beta-lactamase_625_S233A,beta-lactamase_625_233,TEM-1,beta-lactamase_625,P62593,0.985142,NO,233,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.886,-2.424,0.538,,0.016,E,B,0.27,-1.01,1.773,,77.62,BPO,-1.17267,0.213352,0.00311415,0.985142 beta-lactamase_625_D99Y,beta-lactamase_625_99,TEM-1,beta-lactamase_625,P62593,0.985147,NO,99,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.191,-4.234,3.043,,0.402,G,A,0.75,0.36,1.318,,64.69,PAH,-1.794,0.213352,0.00305446,0.985147 beta-lactamase_156_T264N,beta-lactamase_156_264,TEM-1,beta-lactamase_156,P62593,0.985148,NO,264,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.111618,0.0119399,0.985148 beta-lactamase_39_R189P,beta-lactamase_39_189,TEM-1,beta-lactamase_39,P62593,0.985155,NO,189,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.844,-3.964,2.12,,0.278,H,A,1.2,1.01,12.11,12.11,72.73,HBB,-1.668,0.0495842,0.0050699,0.985155 beta-lactamase_156_K213E,beta-lactamase_156_213,TEM-1,beta-lactamase_156,P62593,0.985162,NO,213,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.81,-2.688,0.878,,0.67,,A,2.34,0.29,3.924,,67.83,ABH,-1.57767,0.111618,0.00610411,0.985162 beta-lactamase_625_Y44V,beta-lactamase_625_44,TEM-1,beta-lactamase_625,P62593,0.985168,NO,44,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-2.547,-1.805,-0.742,,,E,B,0.21,-0.45,2.371,,73.78,OHH,-1.86267,0.213352,0.00426364,0.985168 beta-lactamase_625_T198N,beta-lactamase_625_198,TEM-1,beta-lactamase_625,P62593,0.98517,NO,198,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.168,-3.569,1.401,,0.489,,B,0.22,-0.13,0.37,,73.78,HPH,-1.98767,0.213352,0.004311,0.98517 beta-lactamase_156_I206D,beta-lactamase_156_206,TEM-1,beta-lactamase_156,P62593,0.985171,NO,206,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-2.429,-3.794,1.365,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.111618,0.00528934,0.985171 beta-lactamase_2500_Q37Y,beta-lactamase_2500_37,TEM-1,beta-lactamase_2500,P62593,0.985175,NO,37,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.134,-4.193,2.059,,0.613,H,A,0.64,1.98,1.318,,73.08,APH,-2.06967,0.361275,0.00425833,0.985175 beta-lactamase_2500_N173R,beta-lactamase_2500_173,TEM-1,beta-lactamase_2500,P62593,0.985176,NO,173,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-2.663,-3.837,1.174,,1.044,T,l,0.61,1.25,1.88,,77.62,OPA,-1.46633,0.361275,0.0033769,0.985176 gb1_Y271F,gb1_271,gb1,gb1,P06654,0.985178,NO,271,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-1.181,-2.719,1.538,,,,,,,,,,PHA,-1.92933,0.177985,0.00236544,0.985178 beta-lactamase_156_K254G,beta-lactamase_156_254,TEM-1,beta-lactamase_156,P62593,0.985189,NO,254,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.111618,0.00369,0.985189 beta-lactamase_39_L79S,beta-lactamase_39_79,TEM-1,beta-lactamase_39,P62593,0.985203,NO,79,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.842,-3.608,2.766,,0.007,H,A,0.55,-0.16,0.823,,50.35,HHP,-1.44333,0.0495842,0.000947397,0.985203 beta-lactamase_156_L120F,beta-lactamase_156_120,TEM-1,beta-lactamase_156,P62593,0.98521,NO,120,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.044,-2.785,1.741,,,H,A,0.55,-1.13,7.813,,64.69,AHO,-1.13633,0.111618,0.00143563,0.98521 beta-lactamase_2500_V157A,beta-lactamase_2500_157,TEM-1,beta-lactamase_2500,P62593,0.985214,NO,157,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.751,-2.656,0.905,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.361275,0.00506849,0.985214 beta-lactamase_625_M115L,beta-lactamase_625_115,TEM-1,beta-lactamase_625,P62593,0.985214,NO,115,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.389,-1.859,0.47,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.213352,0.0034337,0.985214 beta-lactamase_V72V,beta-lactamase_72,TEM-1,beta-lactamase,P62593,0.985217,NO,72,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.658,-1.658,,5.80324,,H,A,2.78,-1.03,2.964,,65.73,BHH,-1.32167,0.221079,0.00501194,0.985217 beta-lactamase_2500_R92Y,beta-lactamase_2500_92,TEM-1,beta-lactamase_2500,P62593,0.985218,NO,92,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.718,-4.31,2.592,,0.479,E,B,1.2,1.36,3.069,,65.38,BBH,-1.50367,0.361275,0.00429626,0.985218 beta-lactamase_156_K30E,beta-lactamase_156_30,TEM-1,beta-lactamase_156,P62593,0.985224,NO,30,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-2.307,-2.686,0.379,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.111618,0.00448593,0.985224 Pab1_E161P,Pab1_161,Pab1,Pab1,P04147,0.985224,NO,161,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.474,-3.651,2.177,,0.663,T,a,,1.34,,,,AAP,-1.59067,0.175299,0.00276141,0.985224 beta-lactamase_156_S57Y,beta-lactamase_156_57,TEM-1,beta-lactamase_156,P62593,0.985226,NO,57,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.918,-4.294,2.376,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.111618,0.00492804,0.985226 beta-lactamase_P172Q,beta-lactamase_172,TEM-1,beta-lactamase,P62593,0.985226,NO,172,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.998,-3.965,2.967,5.98941,0.639,T,b,1.1,0.24,2.087,,74.48,HOP,-2.03067,0.221079,0.00312594,0.985226 beta-lactamase_39_H156C,beta-lactamase_39_156,TEM-1,beta-lactamase_39,P62593,0.985227,NO,156,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-3.156,-5.208,2.052,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.0495842,0.00468596,0.985227 beta-lactamase_2500_T193Y,beta-lactamase_2500_193,TEM-1,beta-lactamase_2500,P62593,0.985229,NO,193,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.914,-3.989,2.075,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.361275,0.00482669,0.985229 beta-lactamase_39_T269V,beta-lactamase_39_269,TEM-1,beta-lactamase_39,P62593,0.985232,NO,269,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.156,,,,0.646,H,A,0.53,0.4,3.889,,77.62,HPH,-1.96733,0.0495842,0.00950944,0.985232 beta-lactamase_39_T269Q,beta-lactamase_39_269,TEM-1,beta-lactamase_39,P62593,0.985239,NO,269,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.156,,,,0.646,H,A,0.53,0.4,3.889,,77.62,HPH,-1.96733,0.0495842,0.00950944,0.985239 beta-lactamase_156_T198N,beta-lactamase_156_198,TEM-1,beta-lactamase_156,P62593,0.985247,NO,198,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.168,-3.569,1.401,,0.489,,B,0.22,-0.13,10.771,10.771,73.78,HPH,-1.98767,0.111618,0.004311,0.985247 beta-lactamase_2500_Q86G,beta-lactamase_2500_86,TEM-1,beta-lactamase_2500,P62593,0.985247,NO,86,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.4,-2.887,0.487,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.361275,0.00450027,0.985247 beta-lactamase_2500_L55V,beta-lactamase_2500_55,TEM-1,beta-lactamase_2500,P62593,0.985248,NO,55,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.86,-2.346,0.486,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.361275,0.00403741,0.985248 beta-lactamase_156_K144M,beta-lactamase_156_144,TEM-1,beta-lactamase_156,P62593,0.98525,NO,144,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-2.388,-4.736,2.348,,0.863,H,A,2.34,1.27,2.073,,77.62,OBA,-1.904,0.111618,0.00481141,0.98525 beta-lactamase_39_Y95P,beta-lactamase_39_95,TEM-1,beta-lactamase_39,P62593,0.98525,NO,95,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-1.715,-4.285,2.57,,0.122,,b,0.21,-0.37,2.341,,77.62,BHP,-2.16167,0.0495842,0.00479449,0.98525 kka2_1:1_R122D,kka2_1:1_122,Kka2,kka2_1:1,P00552,0.98525,NO,122,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.175,-2.452,0.277,,0.487,H,A,1.2,0.26,1.356,,71.59,BBH,-1.53833,0.520039,0.00736512,0.98525 beta-lactamase_V29L,beta-lactamase_29,TEM-1,beta-lactamase,P62593,0.985253,NO,29,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-2.856,-3.547,0.691,5.58481,0.733,H,A,0.23,-0.78,1.287,,93.01,HHB,-2.24733,0.221079,0.00318969,0.985253 beta-lactamase_39_G281C,beta-lactamase_39_281,TEM-1,beta-lactamase_39,P62593,0.985257,NO,281,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.0495842,0.0406482,0.985257 beta-lactamase_156_D252F,beta-lactamase_156_252,TEM-1,beta-lactamase_156,P62593,0.985266,NO,252,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.111618,0.00575769,0.985266 beta-lactamase_R238G,beta-lactamase_238,TEM-1,beta-lactamase,P62593,0.985275,NO,238,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.002,-3.495,1.493,5.87663,0.564,T,L,0.45,1.09,4.195,,72.73,ABO,-1.62633,0.221079,0.00743256,0.985275 beta-lactamase_156_D252I,beta-lactamase_156_252,TEM-1,beta-lactamase_156,P62593,0.985276,NO,252,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.111618,0.00575769,0.985276 beta-lactamase_625_L197I,beta-lactamase_625_197,TEM-1,beta-lactamase_625,P62593,0.985276,NO,197,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.853,-2.968,2.115,,0.007,S,B,0.55,0.33,1.756,,60.14,HHP,-1.833,0.213352,0.00144602,0.985276 beta-lactamase_156_D174V,beta-lactamase_156_174,TEM-1,beta-lactamase_156,P62593,0.985279,NO,174,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.738,-3.754,3.016,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.111618,0.00125633,0.985279 beta-lactamase_0_Y103P,beta-lactamase_0_103,TEM-1,beta-lactamase_0,P62593,0.985283,NO,103,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-1.33,-4.138,2.808,,0.613,S,l,0.21,1.21,1.646,,63.29,AHP,-1.48767,0.0500837,0.00443048,0.985283 PSD95pdz3_G344N,PSD95pdz3_344,PSD95pdz3,PSD95pdz3,P31016,0.985288,NO,344,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.008,-3.13,2.122,4.83855,,,,,14.06,,,,HOO,-1.10767,0.0758425,0.00078498,0.985288 beta-lactamase_L199R,beta-lactamase_199,TEM-1,beta-lactamase,P62593,0.985289,NO,199,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-2.942,-3.181,0.239,5.57712,0.832,H,A,0.82,0.42,15.302,15.302,77.62,PHH,-2.32933,0.221079,0.0048649,0.985289 beta-lactamase_156_D113M,beta-lactamase_156_113,TEM-1,beta-lactamase_156,P62593,0.98529,NO,113,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.829,-4.826,2.997,,0.665,T,A,0.75,0.91,2.973,,73.08,PAO,-1.703,0.111618,0.00474112,0.98529 beta-lactamase_156_P224A,beta-lactamase_156_224,TEM-1,beta-lactamase_156,P62593,0.98529,NO,224,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.893,-3.071,2.178,,0.383,,B,0.52,-0.3,0.383,,74.48,HOH,-1.26433,0.111618,0.00189564,0.98529 beta-lactamase_39_M209V,beta-lactamase_39_209,TEM-1,beta-lactamase_39,P62593,0.98529,NO,209,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.442,-2.446,1.004,,,H,A,0.55,-0.97,1.167,,64.69,HHA,-1.52633,0.0495842,0.00625021,0.98529 beta-lactamase_156_T139W,beta-lactamase_156_139,TEM-1,beta-lactamase_156,P62593,0.985294,NO,139,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.901,-5.432,3.531,,0.216,H,A,0.22,0.39,16.34,16.34,77.62,PPH,-2.04667,0.111618,0.00441837,0.985294 beta-lactamase_156_E46Y,beta-lactamase_156_46,TEM-1,beta-lactamase_156,P62593,0.9853,NO,46,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.94,-4.198,2.258,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.111618,0.00427568,0.9853 beta-lactamase_2500_P217A,beta-lactamase_2500_217,TEM-1,beta-lactamase_2500,P62593,0.9853,NO,217,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-2.062,-1.891,-0.171,,0.496,I,A,0.52,-0.33,0.431,,74.48,OOH,-1.64333,0.361275,0.00463211,0.9853 beta-lactamase_39_G253T,beta-lactamase_39_253,TEM-1,beta-lactamase_39,P62593,0.985308,NO,253,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.0495842,0.00786358,0.985308 beta-lactamase_39_S57R,beta-lactamase_39_57,TEM-1,beta-lactamase_39,P62593,0.985308,NO,57,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.918,-3.069,1.151,,0.352,E,B,0.27,-0.18,2.3,,72.73,APH,-2.29167,0.0495842,0.00492804,0.985308 beta-lactamase_2500_N98S,beta-lactamase_2500_98,TEM-1,beta-lactamase_2500,P62593,0.98531,NO,98,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-2.973,-2.34,-0.633,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.361275,0.00505389,0.98531 beta-lactamase_E145Q,beta-lactamase_145,TEM-1,beta-lactamase,P62593,0.985318,NO,145,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.357,-2.979,0.622,5.38104,0.545,H,A,0.52,0.79,2.124,,77.62,BAH,-2.069,0.221079,0.00553285,0.985318 beta-lactamase_K252I,beta-lactamase_252,TEM-1,beta-lactamase,P62593,0.985318,NO,252,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.94,-4.216,2.276,5.56823,0.766,,B,1.82,1.16,21.796,21.796,67.83,OBO,-2.03333,0.221079,0.00575769,0.985318 PSD95pdz3_G345S,PSD95pdz3_345,PSD95pdz3,PSD95pdz3,P31016,0.985319,NO,345,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.008,-2.842,1.834,4.32868,,,,,13.165,,,,OOO,-1.084,0.0758425,0.000771806,0.985319 beta-lactamase_39_A225C,beta-lactamase_39_225,TEM-1,beta-lactamase_39,P62593,0.985324,NO,225,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.845,-5.105,3.26,,1,T,B,0.46,-0.38,9.874,9.874,74.48,OHO,-1.39967,0.0495842,0.00465057,0.985324 beta-lactamase_39_W163P,beta-lactamase_39_163,TEM-1,beta-lactamase_39,P62593,0.985329,NO,163,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-1.843,-4.201,2.358,,0.467,,B,0.47,-0.5,15.095,15.095,63.99,BHA,-1.269,0.0495842,0.00418955,0.985329 beta-lactamase_39_R176A,beta-lactamase_39_176,TEM-1,beta-lactamase_39,P62593,0.985331,NO,176,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-0.863,-3.078,2.215,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.0495842,0.00105554,0.985331 beta-lactamase_M66L,beta-lactamase_66,TEM-1,beta-lactamase,P62593,0.985331,NO,66,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.362,-1.674,0.312,5.29561,0.013,,A,1.3,-0.7,1.319,,73.08,OHH,-1.49567,0.221079,0.00412876,0.985331 beta-lactamase_625_P255K,beta-lactamase_625_255,TEM-1,beta-lactamase_625,P62593,0.985332,NO,255,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.213352,0.00499612,0.985332 beta-lactamase_39_Q97T,beta-lactamase_39_97,TEM-1,beta-lactamase_39,P62593,0.985333,NO,97,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.072,-2.713,0.641,,0.823,G,A,0.64,2.42,4.457,,77.62,PPP,-2.43833,0.0495842,0.0045116,0.985333 beta-lactamase_39_Y95L,beta-lactamase_39_95,TEM-1,beta-lactamase_39,P62593,0.98534,NO,95,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-1.715,-2.545,0.83,,0.122,,b,0.21,-0.37,2.341,,77.62,BHP,-2.16167,0.0495842,0.00479449,0.98534 beta-lactamase_0_V106T,beta-lactamase_0_106,TEM-1,beta-lactamase_0,P62593,0.985347,NO,106,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.218,-3.428,2.21,,0.258,T,A,0.44,0.24,0.952,,72.73,OHP,-1.04933,0.0500837,0.00304168,0.985347 WW_domain_V171T,WW_domain_171,Yap65,WW_domain,P46937,0.985347,NO,171,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.547,-3.2,1.653,,,,,,,3.459,,70.24,AHO,-1.265,0.153962,0.00184125,0.985347 beta-lactamase_39_G52A,beta-lactamase_39_52,TEM-1,beta-lactamase_39,P62593,0.98535,NO,52,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.149,-2.316,1.167,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.0495842,0.00340138,0.98535 beta-lactamase_156_V78T,beta-lactamase_156_78,TEM-1,beta-lactamase_156,P62593,0.985355,NO,78,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.459,-3.492,2.033,,,H,A,0.44,-0.47,1.132,,63.64,HHH,-1.17833,0.111618,0.00492501,0.985355 beta-lactamase_625_A40N,beta-lactamase_625_40,TEM-1,beta-lactamase_625,P62593,0.985362,NO,40,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.402,-3.756,2.354,,0.155,S,B,0.46,0.21,1.357,,73.78,OHB,-1.40267,0.213352,0.00490026,0.985362 beta-lactamase_39_V259M,beta-lactamase_39_259,TEM-1,beta-lactamase_39,P62593,0.985364,NO,259,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.0495842,0.0070773,0.985364 beta-lactamase_2500_H94T,beta-lactamase_2500_94,TEM-1,beta-lactamase_2500,P62593,0.985366,NO,94,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-2.5,-2.6,0.1,,0.776,,B,0.17,1.24,1.176,,77.62,HBH,-1.872,0.361275,0.00389226,0.985366 beta-lactamase_156_N50A,beta-lactamase_156_50,TEM-1,beta-lactamase_156,P62593,0.985375,NO,50,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-2.979,-1.868,-1.111,,0.912,T,A,0.61,1.24,13.295,13.295,77.62,HPP,-2.134,0.111618,0.0047211,0.985375 beta-lactamase_39_A215L,beta-lactamase_39_215,TEM-1,beta-lactamase_39,P62593,0.985375,NO,215,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.503,-3.475,1.972,,,,a,0.46,-0.93,0.494,,74.48,HHO,-1.42633,0.0495842,0.00544007,0.985375 beta-lactamase_625_D33A,beta-lactamase_625_33,TEM-1,beta-lactamase_625,P62593,0.985376,NO,33,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.321,-2.241,-0.08,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.213352,0.00435556,0.985376 beta-lactamase_39_W288L,beta-lactamase_39_288,TEM-1,beta-lactamase_39,P62593,0.985382,NO,288,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,,,,,,,,,,,,,BHO,,0.0495842,,0.985382 beta-lactamase_156_Y103N,beta-lactamase_156_103,TEM-1,beta-lactamase_156,P62593,0.985389,NO,103,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-1.33,-2.825,1.495,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.111618,0.00443048,0.985389 beta-lactamase_0_G194D,beta-lactamase_0_194,TEM-1,beta-lactamase_0,P62593,0.98539,NO,194,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.396,-2.314,0.918,,0.276,S,b,0.29,0.36,3.017,,67.83,POA,-1.832,0.0500837,0.00392163,0.98539 beta-lactamase_0_M270W,beta-lactamase_0_270,TEM-1,beta-lactamase_0,P62593,0.985393,NO,270,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.0500837,0.00767762,0.985393 Pab1_A158V,Pab1_158,Pab1,Pab1,P04147,0.985394,NO,158,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.154,-2.054,0.9,,,,,,,1.197,,56.33,HHP,-1.40733,0.175299,0.000649733,0.985394 beta-lactamase_0_A185E,beta-lactamase_0_185,TEM-1,beta-lactamase_0,P62593,0.9854,NO,185,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.406,-3.679,2.273,,,H,A,0.46,-1.02,1.203,,65.03,HHP,-1.84033,0.0500837,0.00467449,0.9854 beta-lactamase_625_I125C,beta-lactamase_625_125,TEM-1,beta-lactamase_625,P62593,0.9854,NO,125,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.441,-4.783,3.342,,,H,A,0.48,-0.7,2.034,,63.29,HHP,-1.248,0.213352,0.00383964,0.9854 beta-lactamase_2500_N98H,beta-lactamase_2500_98,TEM-1,beta-lactamase_2500,P62593,0.985406,NO,98,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-2.973,-3.344,0.371,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.361275,0.00505389,0.985406 beta-lactamase_156_L49R,beta-lactamase_156_49,TEM-1,beta-lactamase_156,P62593,0.985407,NO,49,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.897,-3.032,1.135,,0.131,T,A,0.55,0.04,3.112,,64.69,AHP,-1.99233,0.111618,0.00401477,0.985407 beta-lactamase_625_G52N,beta-lactamase_625_52,TEM-1,beta-lactamase_625,P62593,0.985408,NO,52,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.149,-3.58,2.431,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.213352,0.00340138,0.985408 beta-lactamase_39_I125N,beta-lactamase_39_125,TEM-1,beta-lactamase_39,P62593,0.985413,NO,125,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.441,-4.089,2.648,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.0495842,0.00383964,0.985413 beta-lactamase_0_G236W,beta-lactamase_0_236,TEM-1,beta-lactamase_0,P62593,0.985415,NO,236,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.784,-5.189,4.405,,0.241,,b,0.29,-0.59,3.506,,64.69,HOO,-1.025,0.0500837,0.00162372,0.985415 beta-lactamase_39_H156K,beta-lactamase_39_156,TEM-1,beta-lactamase_39,P62593,0.985415,NO,156,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-3.156,-2.967,-0.189,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.0495842,0.00468596,0.985415 beta-lactamase_2500_Q204E,beta-lactamase_2500_204,TEM-1,beta-lactamase_2500,P62593,0.985418,NO,204,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-1.382,-3.106,1.724,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.361275,0.00364106,0.985418 PSD95pdz3_A378F,PSD95pdz3_378,PSD95pdz3,PSD95pdz3,P31016,0.985425,NO,378,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.307,-3.749,2.442,4.86582,,,,,14.576,,,,HHH,-1.509,0.0758425,0.000313169,0.985425 beta-lactamase_156_E175N,beta-lactamase_156_175,TEM-1,beta-lactamase_156,P62593,0.985428,NO,175,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.336,-3.857,1.521,,0.551,,A,1.04,1.05,2.334,,77.62,AAB,-1.31233,0.111618,0.00482205,0.985428 beta-lactamase_625_L146F,beta-lactamase_625_146,TEM-1,beta-lactamase_625,P62593,0.985434,NO,146,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.462,-2.298,0.836,,0.007,H,A,0.55,-0.56,2.16,,64.69,AHP,-1.656,0.213352,0.00474542,0.985434 beta-lactamase_156_E195N,beta-lactamase_156_195,TEM-1,beta-lactamase_156,P62593,0.98544,NO,195,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.186,-2.977,0.791,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.111618,0.00496565,0.98544 beta-lactamase_N173Y,beta-lactamase_173,TEM-1,beta-lactamase,P62593,0.985443,NO,173,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-2.663,-4.409,1.746,7.02497,1.044,T,l,0.09,1.25,1.88,,77.62,OPA,-1.46633,0.221079,0.0033769,0.985443 beta-lactamase_156_H151M,beta-lactamase_156_151,TEM-1,beta-lactamase_156,P62593,0.985444,NO,151,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-2.96,-4.581,1.621,,0.594,H,A,0.17,0.1,1.401,,77.62,HBP,-2.34767,0.111618,0.00216946,0.985444 beta-lactamase_156_N134S,beta-lactamase_156_134,TEM-1,beta-lactamase_156,P62593,0.985445,NO,134,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-0.879,-2.985,2.106,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.111618,0.000644786,0.985445 beta-lactamase_625_L199D,beta-lactamase_625_199,TEM-1,beta-lactamase_625,P62593,0.985445,NO,199,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-2.942,-3.009,0.067,,0.832,H,A,0.55,0.42,1.552,,77.62,PHH,-2.32933,0.213352,0.0048649,0.985445 beta-lactamase_39_W227H,beta-lactamase_39_227,TEM-1,beta-lactamase_39,P62593,0.985447,NO,227,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-0.982,-4.704,3.722,,0.272,,B,0.47,-0.29,1.37,,74.48,OHH,-1.595,0.0495842,0.00226019,0.985447 beta-lactamase_156_R81T,beta-lactamase_156_81,TEM-1,beta-lactamase_156,P62593,0.985449,NO,81,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.466,-3.547,2.081,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.111618,0.00499763,0.985449 beta-lactamase_625_T264V,beta-lactamase_625_264,TEM-1,beta-lactamase_625,P62593,0.985455,NO,264,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.213352,0.0119399,0.985455 beta-lactamase_39_D48A,beta-lactamase_39_48,TEM-1,beta-lactamase_39,P62593,0.985467,NO,48,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.101,-2.565,1.464,,0.189,E,B,0.75,0.21,0.735,,50.35,HAH,-1.62467,0.0495842,0.0027273,0.985467 beta-lactamase_156_L89N,beta-lactamase_156_89,TEM-1,beta-lactamase_156,P62593,0.985482,NO,89,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.096,-4.11,3.014,,0.168,T,A,0.55,0.63,2.633,,64.34,PHO,-1.75767,0.111618,0.00207068,0.985482 beta-lactamase_39_H94G,beta-lactamase_39_94,TEM-1,beta-lactamase_39,P62593,0.985485,NO,94,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-2.5,-3.593,1.093,,0.776,,B,0.17,1.24,11.583,11.583,77.62,HBH,-1.872,0.0495842,0.00389226,0.985485 beta-lactamase_39_W288M,beta-lactamase_39_288,TEM-1,beta-lactamase_39,P62593,0.985486,NO,288,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,,,,,,,,,,,,,BHO,,0.0495842,,0.985486 beta-lactamase_2500_A183T,beta-lactamase_2500_183,TEM-1,beta-lactamase_2500,P62593,0.985491,NO,183,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.231,-3.281,2.05,,0.155,H,A,0.46,-0.91,12.189,,77.62,HHH,-1.53367,0.361275,0.00296631,0.985491 beta-lactamase_39_L248S,beta-lactamase_39_248,TEM-1,beta-lactamase_39,P62593,0.985494,NO,248,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.0495842,0.00428493,0.985494 beta-lactamase_156_Q276S,beta-lactamase_156_276,TEM-1,beta-lactamase_156,P62593,0.985499,NO,276,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.111618,0.0191712,0.985499 beta-lactamase_2500_T138W,beta-lactamase_2500_138,TEM-1,beta-lactamase_2500,P62593,0.985502,NO,138,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.506,-5.551,3.045,,0.662,H,A,0.22,-0.03,30.445,30.445,73.78,HPP,-1.81233,0.361275,0.00487868,0.985502 beta-lactamase_39_R257L,beta-lactamase_39_257,TEM-1,beta-lactamase_39,P62593,0.985507,NO,257,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.0495842,0.00756629,0.985507 beta-lactamase_156_K190M,beta-lactamase_156_190,TEM-1,beta-lactamase_156,P62593,0.985512,NO,190,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.994,-4.714,2.72,,0.371,H,A,2.34,0.16,1.513,,77.62,BBH,-1.64167,0.111618,0.00574527,0.985512 beta-lactamase_39_P224D,beta-lactamase_39_224,TEM-1,beta-lactamase_39,P62593,0.985515,NO,224,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.893,-3.513,2.62,,0.383,,B,0.52,-0.3,3.169,,74.48,HOH,-1.26433,0.0495842,0.00189564,0.985515 beta-lactamase_39_I54L,beta-lactamase_39_54,TEM-1,beta-lactamase_39,P62593,0.985517,NO,54,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-2.838,-2.471,-0.367,,0.669,E,B,0.48,-0.14,1.349,,73.78,BHH,-2.337,0.0495842,0.00403589,0.985517 beta-lactamase_39_V117H,beta-lactamase_39_117,TEM-1,beta-lactamase_39,P62593,0.985522,NO,117,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.53,-4.89,3.36,,,H,A,0.44,-0.34,1.182,,65.03,PHB,-1.741,0.0495842,0.00467906,0.985522 beta-lactamase_625_G85H,beta-lactamase_625_85,TEM-1,beta-lactamase_625,P62593,0.985522,NO,85,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.011,-4.646,3.635,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.213352,0.00252173,0.985522 beta-lactamase_625_S80A,beta-lactamase_625_80,TEM-1,beta-lactamase_625,P62593,0.985524,NO,80,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.029,-1.631,-0.398,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.213352,0.00565569,0.985524 beta-lactamase_L150C,beta-lactamase_150,TEM-1,beta-lactamase,P62593,0.985529,NO,150,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.326,-4.732,3.406,5.15566,,H,A,1.75,-0.2,1.615,,62.94,HHB,-1.86167,0.221079,0.00463171,0.985529 beta-lactamase_156_L38N,beta-lactamase_156_38,TEM-1,beta-lactamase_156,P62593,0.985537,NO,38,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.343,-4.007,2.664,,0.088,H,A,0.55,0.2,13.556,13.556,64.34,PHO,-1.78033,0.111618,0.00373244,0.985537 beta-lactamase_625_L89S,beta-lactamase_625_89,TEM-1,beta-lactamase_625,P62593,0.98555,NO,89,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.096,-3.54,2.444,,0.168,T,A,0.55,0.63,1.599,,64.34,PHO,-1.75767,0.213352,0.00207068,0.98555 beta-lactamase_39_Q97S,beta-lactamase_39_97,TEM-1,beta-lactamase_39,P62593,0.985551,NO,97,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.072,-3.388,1.316,,0.823,G,A,0.64,2.42,4.457,,77.62,PPP,-2.43833,0.0495842,0.0045116,0.985551 beta-lactamase_156_Q203G,beta-lactamase_156_203,TEM-1,beta-lactamase_156,P62593,0.985554,NO,203,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.168,-2.805,0.637,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.111618,0.00631514,0.985554 beta-lactamase_156_E119H,beta-lactamase_156_119,TEM-1,beta-lactamase_156,P62593,0.985556,NO,119,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.412,-4.521,3.109,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.111618,0.00386966,0.985556 kka2_1:8_Y244C,kka2_1:8_244,Kka2,kka2_1:8,P00552,0.985559,NO,244,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-0.775,-4.89,4.115,,0.066,H,A,1.25,-0.64,,,,HHO,-1.41267,0.100394,0.00453187,0.985559 kka2_1:8_Y244C,kka2_1:8_244,Kka2,kka2_1:8,P00552,0.985559,NO,244,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-0.775,-4.89,4.115,,0.066,H,A,1.25,-0.64,,,,HHO,-1.41267,0.100394,0.00453187,0.985559 beta-lactamase_2500_A225M,beta-lactamase_2500_225,TEM-1,beta-lactamase_2500,P62593,0.985564,NO,225,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.845,-4.778,2.933,,1,T,B,0.46,-0.38,0.551,,74.48,OHO,-1.39967,0.361275,0.00465057,0.985564 hsp90_Q582P,hsp90_582,hsp90,hsp90,P02829,0.985565,NO,582,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-3.278,-3.033,0,4.91603,0.453,S,B,,0.67,,,,OPH,-3.249,0.368192,0.000222939,0.985565 beta-lactamase_156_L28S,beta-lactamase_156_28,TEM-1,beta-lactamase_156,P62593,0.985568,NO,28,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.579,-3.523,1.944,,0.277,H,A,0.55,-0.16,3.262,,93.01,PHH,-2.11333,0.111618,0.00359321,0.985568 beta-lactamase_625_R81H,beta-lactamase_625_81,TEM-1,beta-lactamase_625,P62593,0.985569,NO,81,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.466,-4.464,2.998,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.213352,0.00499763,0.985569 beta-lactamase_39_G281H,beta-lactamase_39_281,TEM-1,beta-lactamase_39,P62593,0.98557,NO,281,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.0495842,0.0406482,0.98557 beta-lactamase_156_A235N,beta-lactamase_156_235,TEM-1,beta-lactamase_156,P62593,0.985574,NO,235,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.266,-3.746,2.48,,0.32,E,B,0.46,-0.86,1.344,,50,OHO,-0.89,0.111618,0.00493474,0.985574 beta-lactamase_39_A77D,beta-lactamase_39_77,TEM-1,beta-lactamase_39,P62593,0.985574,NO,77,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.234,-3.775,2.541,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.0495842,0.00282362,0.985574 beta-lactamase_156_T178S,beta-lactamase_156_178,TEM-1,beta-lactamase_156,P62593,0.985575,NO,178,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-0.791,-2.936,2.145,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.111618,0.000684366,0.985575 beta-lactamase_625_Y103S,beta-lactamase_625_103,TEM-1,beta-lactamase_625,P62593,0.985576,NO,103,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-1.33,-3.594,2.264,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.213352,0.00443048,0.985576 beta-lactamase_156_V78M,beta-lactamase_156_78,TEM-1,beta-lactamase_156,P62593,0.985582,NO,78,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.459,-2.823,1.364,,,H,A,0.44,-0.47,1.132,,63.64,HHH,-1.17833,0.111618,0.00492501,0.985582 beta-lactamase_A276F,beta-lactamase_276,TEM-1,beta-lactamase,P62593,0.985585,NO,276,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.144,-4.125,2.981,5.1387,0.117,H,A,0.52,-0.84,1.283,,44.06,HHA,-1.47,0.221079,0.0191712,0.985585 beta-lactamase_A77Y,beta-lactamase_77,TEM-1,beta-lactamase,P62593,0.985585,NO,77,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.234,-4.173,2.939,4.75777,0.039,H,A,0.52,-0.56,1.708,,64.34,OHH,-1.294,0.221079,0.00282362,0.985585 beta-lactamase_A9H,beta-lactamase_9,TEM-1,beta-lactamase,P62593,0.985585,NO,9,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.147,-4.692,2.545,,,,,,,5.128,,72.73,HHH,-2.04267,0.221079,0.00247263,0.985585 beta-lactamase_E270I,beta-lactamase_270,TEM-1,beta-lactamase,P62593,0.985585,NO,270,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.723,-3.927,2.204,5.33196,0.422,H,A,0.52,1.15,1.745,,64.34,AAB,-1.70933,0.221079,0.00767762,0.985585 beta-lactamase_F22Q,beta-lactamase_22,TEM-1,beta-lactamase,P62593,0.985585,NO,22,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-2.676,-3.06,0.384,,,,,,,1.616,,73.08,HHH,-2.03233,0.221079,0.00262842,0.985585 beta-lactamase_H156E,beta-lactamase_156,TEM-1,beta-lactamase,P62593,0.985585,NO,156,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-3.156,-2.577,-0.579,6.00284,0.753,S,A,0.72,-0.6,6.456,6.456,77.62,ABH,-1.932,0.221079,0.00468596,0.985585 beta-lactamase_K32H,beta-lactamase_32,TEM-1,beta-lactamase,P62593,0.985585,NO,32,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.984,-4.632,2.648,5.55842,0.563,H,A,1.82,0.34,1.754,,73.08,HBA,-2.04233,0.221079,0.00401283,0.985585 beta-lactamase_Q203L,beta-lactamase_203,TEM-1,beta-lactamase,P62593,0.985585,NO,203,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.168,-2.697,0.529,5.65296,0.47,H,A,0.12,-0.38,1.66,,65.38,BPP,-1.614,0.221079,0.00631514,0.985585 beta-lactamase_T198H,beta-lactamase_198,TEM-1,beta-lactamase,P62593,0.985585,NO,198,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.168,-3.211,1.043,4.9209,0.489,,B,0.69,-0.13,0.37,,73.78,HPH,-1.98767,0.221079,0.004311,0.985585 beta-lactamase_V101I,beta-lactamase_101,TEM-1,beta-lactamase,P62593,0.985585,NO,101,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.295,-2.207,0.912,5.49045,0.342,,B,0.96,0,1.675,,73.08,HHA,-1.54367,0.221079,0.00374492,0.985585 beta-lactamase_156_L47T,beta-lactamase_156_47,TEM-1,beta-lactamase_156,P62593,0.985589,NO,47,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.876,-2.727,0.851,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.111618,0.00439844,0.985589 Pab1_D151S,Pab1_151,Pab1,Pab1,P04147,0.98559,NO,151,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.399,-3.127,0.728,,,,,,,,,,OAH,-1.51767,0.175299,0.00228155,0.98559 beta-lactamase_156_Q267N,beta-lactamase_156_267,TEM-1,beta-lactamase_156,P62593,0.985593,NO,267,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.111618,0.0102128,0.985593 beta-lactamase_625_Q276V,beta-lactamase_625_276,TEM-1,beta-lactamase_625,P62593,0.985595,NO,276,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.213352,0.0191712,0.985595 beta-lactamase_625_K144P,beta-lactamase_625_144,TEM-1,beta-lactamase_625,P62593,0.985601,NO,144,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-2.388,-2.633,0.245,,0.863,H,A,2.34,1.27,2.313,,77.62,OBA,-1.904,0.213352,0.00481141,0.985601 beta-lactamase_39_S57D,beta-lactamase_39_57,TEM-1,beta-lactamase_39,P62593,0.985607,NO,57,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.918,-3.634,1.716,,0.352,E,B,0.27,-0.18,2.3,,72.73,APH,-2.29167,0.0495842,0.00492804,0.985607 beta-lactamase_625_M115C,beta-lactamase_625_115,TEM-1,beta-lactamase_625,P62593,0.985607,NO,115,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.389,-4.767,3.378,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.213352,0.0034337,0.985607 beta-lactamase_156_V31C,beta-lactamase_156_31,TEM-1,beta-lactamase_156,P62593,0.985611,NO,31,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.822,-3.252,1.43,,,H,A,0.44,-0.46,4.126,,73.78,BHB,-2.03767,0.111618,0.00478065,0.985611 beta-lactamase_2500_T138H,beta-lactamase_2500_138,TEM-1,beta-lactamase_2500,P62593,0.985611,NO,138,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.506,-4.649,2.143,,0.662,H,A,0.22,-0.03,30.445,30.445,73.78,HPP,-1.81233,0.361275,0.00487868,0.985611 beta-lactamase_2500_N98V,beta-lactamase_2500_98,TEM-1,beta-lactamase_2500,P62593,0.985613,NO,98,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-2.973,-3.696,0.723,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.361275,0.00505389,0.985613 beta-lactamase_625_M153G,beta-lactamase_625_153,TEM-1,beta-lactamase_625,P62593,0.985615,NO,153,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-3.193,-3.633,0.44,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.213352,0.00509109,0.985615 beta-lactamase_39_L284C,beta-lactamase_39_284,TEM-1,beta-lactamase_39,P62593,0.985616,NO,284,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.0495842,0.0686156,0.985616 beta-lactamase_156_D252T,beta-lactamase_156_252,TEM-1,beta-lactamase_156,P62593,0.985623,NO,252,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.111618,0.00575769,0.985623 beta-lactamase_2500_V117M,beta-lactamase_2500_117,TEM-1,beta-lactamase_2500,P62593,0.985623,NO,117,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.53,-3.063,1.533,,,H,A,0.44,-0.34,1.23,,65.03,PHB,-1.741,0.361275,0.00467906,0.985623 beta-lactamase_156_G142R,beta-lactamase_156_142,TEM-1,beta-lactamase_156,P62593,0.985627,NO,142,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.707,-3.93,3.223,,0.034,,p,0.29,-0.64,0.325,,64.69,OOO,-0.834,0.111618,0.00060149,0.985627 beta-lactamase_625_A182D,beta-lactamase_625_182,TEM-1,beta-lactamase_625,P62593,0.985628,NO,182,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.777,-2.705,0.928,,0.136,H,A,0.46,-0.66,16.784,16.784,93.01,OHH,-1.27367,0.213352,0.00559099,0.985628 beta-lactamase_39_I261A,beta-lactamase_39_261,TEM-1,beta-lactamase_39,P62593,0.98563,NO,261,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.0495842,0.0123091,0.98563 beta-lactamase_39_A182P,beta-lactamase_39_182,TEM-1,beta-lactamase_39,P62593,0.985631,NO,182,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.777,-3.952,2.175,,0.136,H,A,0.46,-0.66,2.598,,93.01,OHH,-1.27367,0.0495842,0.00559099,0.985631 beta-lactamase_39_L100V,beta-lactamase_39_100,TEM-1,beta-lactamase_39,P62593,0.985631,NO,100,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.218,-2.049,0.831,,0.343,,B,0.55,0.13,8.311,,63.29,AHH,-1.23467,0.0495842,0.00413885,0.985631 beta-lactamase_156_T269G,beta-lactamase_156_269,TEM-1,beta-lactamase_156,P62593,0.985633,NO,269,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.111618,0.00950944,0.985633 beta-lactamase_156_R176Y,beta-lactamase_156_176,TEM-1,beta-lactamase_156,P62593,0.985638,NO,176,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-0.863,-4.162,3.299,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.111618,0.00105554,0.985638 beta-lactamase_625_G253C,beta-lactamase_625_253,TEM-1,beta-lactamase_625,P62593,0.98564,NO,253,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.213352,0.00786358,0.98564 beta-lactamase_156_T126S,beta-lactamase_156_126,TEM-1,beta-lactamase_156,P62593,0.985644,NO,126,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.122,-2.464,1.342,,0.05,H,A,0.22,-0.05,1.14,,44.41,HPH,-1.60467,0.111618,0.00244552,0.985644 beta-lactamase_2500_E169D,beta-lactamase_2500_169,TEM-1,beta-lactamase_2500,P62593,0.985652,NO,169,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.23,-3.13,1.9,,0.337,,A,1.04,1,1.806,,73.08,PAH,-1.16533,0.361275,0.00400994,0.985652 WW_domain_A175F,WW_domain_175,Yap65,WW_domain,P46937,0.985664,NO,175,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.631,-4.181,2.55,6.69537,,,,,,6.257,,83.93,OHO,-1.30033,0.153962,0.00326874,0.985664 beta-lactamase_39_N50Q,beta-lactamase_39_50,TEM-1,beta-lactamase_39,P62593,0.985667,NO,50,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-2.979,-2.653,-0.326,,0.912,T,A,0.61,1.24,10.736,,77.62,HPP,-2.134,0.0495842,0.0047211,0.985667 beta-lactamase_39_R176W,beta-lactamase_39_176,TEM-1,beta-lactamase_39,P62593,0.985671,NO,176,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-0.863,-5.322,4.459,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.0495842,0.00105554,0.985671 beta-lactamase_625_M115V,beta-lactamase_625_115,TEM-1,beta-lactamase_625,P62593,0.985671,NO,115,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.389,-3.055,1.666,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.213352,0.0034337,0.985671 beta-lactamase_625_R189D,beta-lactamase_625_189,TEM-1,beta-lactamase_625,P62593,0.985671,NO,189,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.844,-2.871,1.027,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.213352,0.0050699,0.985671 beta-lactamase_39_R176I,beta-lactamase_39_176,TEM-1,beta-lactamase_39,P62593,0.985679,NO,176,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-0.863,-4.01,3.147,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.0495842,0.00105554,0.985679 beta-lactamase_2500_S122T,beta-lactamase_2500_122,TEM-1,beta-lactamase_2500,P62593,0.985691,NO,122,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.406,-2.952,0.546,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.361275,0.00497825,0.985691 beta-lactamase_156_K30I,beta-lactamase_156_30,TEM-1,beta-lactamase_156,P62593,0.985693,NO,30,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-2.307,-3.856,1.549,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.111618,0.00448593,0.985693 beta-lactamase_625_N98L,beta-lactamase_625_98,TEM-1,beta-lactamase_625,P62593,0.985701,NO,98,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-2.973,-3.59,0.617,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.213352,0.00505389,0.985701 gb1_N234G,gb1_234,gb1,gb1,P06654,0.985706,NO,234,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-2.055,-3.048,0.993,,,,,,,1.235,,45.54,HPO,-2.05067,0.177985,0.00242189,0.985706 beta-lactamase_625_V214N,beta-lactamase_625_214,TEM-1,beta-lactamase_625,P62593,0.985707,NO,214,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.299,-3.962,2.663,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.213352,0.00628442,0.985707 beta-lactamase_625_I125V,beta-lactamase_625_125,TEM-1,beta-lactamase_625,P62593,0.985713,NO,125,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.441,-2.101,0.66,,,H,A,0.48,-0.7,2.034,,63.29,HHP,-1.248,0.213352,0.00383964,0.985713 beta-lactamase_T139S,beta-lactamase_139,TEM-1,beta-lactamase,P62593,0.985715,NO,139,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.901,-2.265,0.364,5.69095,0.216,H,A,0.3,0.39,2.256,,77.62,PPH,-2.04667,0.221079,0.00441837,0.985715 beta-lactamase_39_W163K,beta-lactamase_39_163,TEM-1,beta-lactamase_39,P62593,0.985716,NO,163,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-1.843,-2.971,1.128,,0.467,,B,0.47,-0.5,15.095,15.095,63.99,BHA,-1.269,0.0495842,0.00418955,0.985716 beta-lactamase_625_T139S,beta-lactamase_625_139,TEM-1,beta-lactamase_625,P62593,0.98573,NO,139,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.901,-2.265,0.364,,0.216,H,A,0.22,0.39,2.256,,77.62,PPH,-2.04667,0.213352,0.00441837,0.98573 kka2_1:8_I228L,kka2_1:8_228,Kka2,kka2_1:8,P00552,0.98573,NO,228,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.142,-1.811,0.669,,,H,A,1.52,-1.2,1.521,,71.59,AHH,-1.54633,0.100394,0.00458834,0.98573 kka2_1:8_I228L,kka2_1:8_228,Kka2,kka2_1:8,P00552,0.98573,NO,228,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.142,-1.811,0.669,,,H,A,1.52,-1.2,1.521,,71.59,AHH,-1.54633,0.100394,0.00458834,0.98573 WW_domain_S184T,WW_domain_184,Yap65,WW_domain,P46937,0.98573,NO,184,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.363,-1.928,0.565,5.06696,,,,,,,,,PPO,-1.39133,0.153962,0.00231095,0.98573 beta-lactamase_156_Q204G,beta-lactamase_156_204,TEM-1,beta-lactamase_156,P62593,0.985735,NO,204,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-1.382,-3.474,2.092,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.111618,0.00364106,0.985735 beta-lactamase_625_S241T,beta-lactamase_625_241,TEM-1,beta-lactamase_625,P62593,0.985738,NO,241,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.213352,0.00452736,0.985738 beta-lactamase_2500_R275K,beta-lactamase_2500_275,TEM-1,beta-lactamase_2500,P62593,0.985743,NO,275,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.361275,0.0141984,0.985743 beta-lactamase_625_E279K,beta-lactamase_625_279,TEM-1,beta-lactamase_625,P62593,0.985743,NO,279,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.213352,0.0192826,0.985743 beta-lactamase_156_G52H,beta-lactamase_156_52,TEM-1,beta-lactamase_156,P62593,0.985752,NO,52,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.149,-4.712,3.563,,0.299,,l,0.29,-0.04,1.179,,64.69,POB,-1.66267,0.111618,0.00340138,0.985752 Pab1_L190P,Pab1_190,Pab1,Pab1,P04147,0.985755,NO,190,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.325,-3.88,2.555,,0.489,E,B,,2.59,,,,HHH,-1.31033,0.175299,0.00132347,0.985755 beta-lactamase_625_F70Y,beta-lactamase_625_70,TEM-1,beta-lactamase_625,P62593,0.985761,NO,70,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.169,-2.563,1.394,,,H,A,0.58,-1.34,1.14,,63.99,PHB,-0.980667,0.213352,0.00193499,0.985761 beta-lactamase_39_L146G,beta-lactamase_39_146,TEM-1,beta-lactamase_39,P62593,0.985763,NO,146,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.462,-3.742,2.28,,0.007,H,A,0.55,-0.56,1.953,,64.69,AHP,-1.656,0.0495842,0.00474542,0.985763 beta-lactamase_39_A200S,beta-lactamase_39_200,TEM-1,beta-lactamase_39,P62593,0.985767,NO,200,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.878,-2.183,0.305,,0.757,H,A,0.46,-0.19,1.54,,77.62,HHP,-2.001,0.0495842,0.0060056,0.985767 beta-lactamase_2500_L28M,beta-lactamase_2500_28,TEM-1,beta-lactamase_2500,P62593,0.985774,NO,28,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.579,-4.156,2.577,,0.277,H,A,0.55,-0.16,2.716,,93.01,PHH,-2.11333,0.361275,0.00359321,0.985774 WW_domain_A175V,WW_domain_175,Yap65,WW_domain,P46937,0.985775,NO,175,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.631,-3.266,1.635,6.69537,,,,,,6.257,,83.93,OHO,-1.30033,0.153962,0.00326874,0.985775 kka2_1:4_Q61F,kka2_1:4_61,Kka2,kka2_1:4,P00552,0.985778,NO,61,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.982,-4.457,1.475,,0.591,H,A,0.64,0.41,3.484,,65.53,HPA,-1.85667,0.168804,0.00612092,0.985778 PSD95pdz3_R368G,PSD95pdz3_368,PSD95pdz3,PSD95pdz3,P31016,0.985787,NO,368,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.582,-3.04,1.458,6.13355,,,,,18.1818,,,,HBP,-1.50033,0.0758425,0.000451517,0.985787 beta-lactamase_625_I229C,beta-lactamase_625_229,TEM-1,beta-lactamase_625,P62593,0.985789,NO,229,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.267,-4.722,3.455,,0.083,E,B,0.48,-0.76,1.69,,50,HHH,-1.58767,0.213352,0.00477249,0.985789 beta-lactamase_E145E,beta-lactamase_145,TEM-1,beta-lactamase,P62593,0.985789,NO,145,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.357,-2.357,,5.38104,0.545,H,A,0.52,0.79,2.124,,77.62,BAH,-2.069,0.221079,0.00553285,0.985789 beta-lactamase_156_G76W,beta-lactamase_156_76,TEM-1,beta-lactamase_156,P62593,0.985793,NO,76,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.189,-5.284,4.095,,,H,A,0.29,-0.67,3.059,,67.83,OOH,-1.22267,0.111618,0.00476637,0.985793 beta-lactamase_S96D,beta-lactamase_96,TEM-1,beta-lactamase,P62593,0.985797,NO,96,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.27,-3.641,1.371,5.29889,0.368,,b,0.25,0.39,32.348,32.348,73.78,HPP,-2.019,0.221079,0.00551835,0.985797 kka2_1:8_R143L,kka2_1:8_143,Kka2,kka2_1:8,P00552,0.985799,NO,143,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.525,-2.21,-0.315,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.100394,0.00662247,0.985799 kka2_1:8_R143L,kka2_1:8_143,Kka2,kka2_1:8,P00552,0.985799,NO,143,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.525,-2.21,-0.315,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.100394,0.00662247,0.985799 beta-lactamase_39_P217L,beta-lactamase_39_217,TEM-1,beta-lactamase_39,P62593,0.985801,NO,217,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-2.062,-3.634,1.572,,0.496,I,A,0.52,-0.33,21.172,21.172,74.48,OOH,-1.64333,0.0495842,0.00463211,0.985801 beta-lactamase_156_P65G,beta-lactamase_156_65,TEM-1,beta-lactamase_156,P62593,0.985804,NO,65,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.894,-3.443,2.549,,0.098,E,B,0.52,-0.62,0.623,,40.56,HOH,-1.03233,0.111618,0.00152776,0.985804 beta-lactamase_A266T,beta-lactamase_266,TEM-1,beta-lactamase,P62593,0.985805,NO,266,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.369,-2.73,1.361,5.02057,0.175,S,B,0.52,0.07,1.832,,64.34,PHP,-2.08567,0.221079,0.0140785,0.985805 beta-lactamase_39_T193V,beta-lactamase_39_193,TEM-1,beta-lactamase_39,P62593,0.985807,NO,193,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.914,-2.673,0.759,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.0495842,0.00482669,0.985807 beta-lactamase_156_R273K,beta-lactamase_156_273,TEM-1,beta-lactamase_156,P62593,0.98581,NO,273,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.314,-2.204,-0.11,,0.564,H,A,1.2,1.57,20.248,20.248,73.78,ABP,-1.841,0.111618,0.0077952,0.98581 beta-lactamase_39_E169N,beta-lactamase_39_169,TEM-1,beta-lactamase_39,P62593,0.985815,NO,169,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.23,-3.55,2.32,,0.337,,A,1.04,1,15.633,15.633,73.08,PAH,-1.16533,0.0495842,0.00400994,0.985815 beta-lactamase_156_I54W,beta-lactamase_156_54,TEM-1,beta-lactamase_156,P62593,0.985816,NO,54,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-2.838,-5.452,2.614,,0.669,E,B,0.48,-0.14,0.541,,73.78,BHH,-2.337,0.111618,0.00403589,0.985816 beta-lactamase_156_G154H,beta-lactamase_156_154,TEM-1,beta-lactamase_156,P62593,0.98582,NO,154,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.823,-4.704,3.881,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.111618,0.00180205,0.98582 beta-lactamase_2500_R189G,beta-lactamase_2500_189,TEM-1,beta-lactamase_2500,P62593,0.985822,NO,189,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.844,-3.504,1.66,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.361275,0.0050699,0.985822 beta-lactamase_39_P172K,beta-lactamase_39_172,TEM-1,beta-lactamase_39,P62593,0.985822,NO,172,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.998,-3.522,2.524,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.0495842,0.00312594,0.985822 beta-lactamase_625_T264R,beta-lactamase_625_264,TEM-1,beta-lactamase_625,P62593,0.985826,NO,264,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.213352,0.0119399,0.985826 beta-lactamase_156_G76S,beta-lactamase_156_76,TEM-1,beta-lactamase_156,P62593,0.985833,NO,76,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.189,-2.528,1.339,,,H,A,0.29,-0.67,3.059,,67.83,OOH,-1.22267,0.111618,0.00476637,0.985833 beta-lactamase_39_L100I,beta-lactamase_39_100,TEM-1,beta-lactamase_39,P62593,0.985846,NO,100,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.218,-1.863,0.645,,0.343,,B,0.55,0.13,8.311,,63.29,AHH,-1.23467,0.0495842,0.00413885,0.985846 beta-lactamase_625_S283A,beta-lactamase_625_283,TEM-1,beta-lactamase_625,P62593,0.985851,NO,283,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.213352,0.0429138,0.985851 beta-lactamase_625_A77F,beta-lactamase_625_77,TEM-1,beta-lactamase_625,P62593,0.985859,NO,77,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.234,-4.125,2.891,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.213352,0.00282362,0.985859 beta-lactamase_2500_A77F,beta-lactamase_2500_77,TEM-1,beta-lactamase_2500,P62593,0.985864,NO,77,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.234,-4.125,2.891,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.361275,0.00282362,0.985864 beta-lactamase_2500_E238S,beta-lactamase_2500_238,TEM-1,beta-lactamase_2500,P62593,0.985864,NO,238,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.361275,0.00743256,0.985864 beta-lactamase_625_L248V,beta-lactamase_625_248,TEM-1,beta-lactamase_625,P62593,0.985867,NO,248,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.213352,0.00428493,0.985867 beta-lactamase_39_S51G,beta-lactamase_39_51,TEM-1,beta-lactamase_39,P62593,0.985869,NO,51,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.526,-2.569,1.043,,0.496,T,A,0.27,0.26,2.964,,72.73,PPO,-1.88467,0.0495842,0.00504821,0.985869 beta-lactamase_625_Q86M,beta-lactamase_625_86,TEM-1,beta-lactamase_625,P62593,0.985869,NO,86,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.4,-3.46,1.06,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.213352,0.00450027,0.985869 beta-lactamase_39_L191Q,beta-lactamase_39_191,TEM-1,beta-lactamase_39,P62593,0.98587,NO,191,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.087,-4.183,3.096,,,H,A,0.55,0.09,1.372,,63.29,BHH,-1.445,0.0495842,0.00263549,0.98587 beta-lactamase_156_G76C,beta-lactamase_156_76,TEM-1,beta-lactamase_156,P62593,0.985874,NO,76,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.189,-4.823,3.634,,,H,A,0.29,-0.67,3.059,,67.83,OOH,-1.22267,0.111618,0.00476637,0.985874 beta-lactamase_625_L79V,beta-lactamase_625_79,TEM-1,beta-lactamase_625,P62593,0.985876,NO,79,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.842,-2.879,2.037,,0.007,H,A,0.55,-0.16,0.935,,50.35,HHP,-1.44333,0.213352,0.000947397,0.985876 beta-lactamase_625_L111T,beta-lactamase_625_111,TEM-1,beta-lactamase_625,P62593,0.985885,NO,111,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.76,-2.765,1.005,,0.328,T,A,0.55,0.93,2.26,,64.34,BHP,-1.884,0.213352,0.00480671,0.985885 beta-lactamase_2500_N98I,beta-lactamase_2500_98,TEM-1,beta-lactamase_2500,P62593,0.985887,NO,98,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-2.973,-4.064,1.091,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.361275,0.00505389,0.985887 beta-lactamase_156_P60E,beta-lactamase_156_60,TEM-1,beta-lactamase_156,P62593,0.98589,NO,60,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-2.469,-2.856,0.387,,0.256,T,A,0.52,-0.56,2.947,,77.62,BOA,-1.97633,0.111618,0.00521318,0.98589 beta-lactamase_0_N274P,beta-lactamase_0_274,TEM-1,beta-lactamase_0,P62593,0.985891,NO,274,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.0500837,0.0110418,0.985891 kka2_1:4_L232M,kka2_1:4_232,Kka2,kka2_1:4,P00552,0.985902,NO,232,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.514,-4.338,2.824,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.168804,0.00800103,0.985902 beta-lactamase_156_A278C,beta-lactamase_156_278,TEM-1,beta-lactamase_156,P62593,0.985914,NO,278,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.111618,0.0310297,0.985914 beta-lactamase_156_L47Y,beta-lactamase_156_47,TEM-1,beta-lactamase_156,P62593,0.985914,NO,47,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.876,-3.117,1.241,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.111618,0.00439844,0.985914 Pab1_A179G,Pab1_179,Pab1,Pab1,P04147,0.985914,NO,179,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.013,-2.725,1.712,,0.078,H,A,0.61,0.5,,,,HHB,-1.51233,0.175299,0.000291703,0.985914 beta-lactamase_156_A40V,beta-lactamase_156_40,TEM-1,beta-lactamase_156,P62593,0.985916,NO,40,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.402,-2.649,1.247,,0.155,S,B,0.46,0.21,1.357,,73.78,OHB,-1.40267,0.111618,0.00490026,0.985916 beta-lactamase_156_M153D,beta-lactamase_156_153,TEM-1,beta-lactamase_156,P62593,0.985919,NO,153,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-3.193,-3.931,0.738,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.111618,0.00509109,0.985919 beta-lactamase_0_D177W,beta-lactamase_0_177,TEM-1,beta-lactamase_0,P62593,0.985921,NO,177,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.967,-5.545,4.578,,0.006,T,L,0.75,-1.02,3.536,,64.69,BAP,-0.873667,0.0500837,0.000864022,0.985921 beta-lactamase_156_Q88H,beta-lactamase_156_88,TEM-1,beta-lactamase_156,P62593,0.985921,NO,88,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.086,-4.599,2.513,,0.807,,B,0.64,2.03,0.911,,77.62,APH,-1.53433,0.111618,0.00504167,0.985921 beta-lactamase_625_R92V,beta-lactamase_625_92,TEM-1,beta-lactamase_625,P62593,0.985921,NO,92,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.718,-2.509,0.791,,0.479,E,B,1.2,1.36,3.069,,65.38,BBH,-1.50367,0.213352,0.00429626,0.985921 beta-lactamase_156_P105D,beta-lactamase_156_105,TEM-1,beta-lactamase_156,P62593,0.98593,NO,105,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.813,-3.466,2.653,,0.226,T,A,0.52,0.8,1.154,,63.29,POH,-1.01533,0.111618,0.0011981,0.98593 beta-lactamase_39_L38V,beta-lactamase_39_38,TEM-1,beta-lactamase_39,P62593,0.985933,NO,38,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.343,-2.209,0.866,,0.088,H,A,0.55,0.2,17.089,17.089,64.34,PHO,-1.78033,0.0495842,0.00373244,0.985933 beta-lactamase_156_T112D,beta-lactamase_156_112,TEM-1,beta-lactamase_156,P62593,0.985943,NO,112,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.186,-2.66,0.474,,0.921,T,A,0.22,1.06,2.87,,73.78,HPA,-1.925,0.111618,0.00531334,0.985943 beta-lactamase_625_H287V,beta-lactamase_625_287,TEM-1,beta-lactamase_625,P62593,0.985943,NO,287,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,,,,,,,,,,,,,BBH,-1.111,0.213352,,0.985943 beta-lactamase_39_P105S,beta-lactamase_39_105,TEM-1,beta-lactamase_39,P62593,0.985951,NO,105,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.813,-2.526,1.713,,0.226,T,A,0.52,0.8,1.222,,63.29,POH,-1.01533,0.0495842,0.0011981,0.985951 beta-lactamase_625_A77T,beta-lactamase_625_77,TEM-1,beta-lactamase_625,P62593,0.985952,NO,77,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.234,-2.687,1.453,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.213352,0.00282362,0.985952 beta-lactamase_625_D33S,beta-lactamase_625_33,TEM-1,beta-lactamase_625,P62593,0.985952,NO,33,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.321,-2.627,0.306,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.213352,0.00435556,0.985952 beta-lactamase_39_T193A,beta-lactamase_39_193,TEM-1,beta-lactamase_39,P62593,0.985954,NO,193,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.914,-2.618,0.704,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.0495842,0.00482669,0.985954 beta-lactamase_D269K,beta-lactamase_269,TEM-1,beta-lactamase,P62593,0.985955,NO,269,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.156,-2.651,0.495,5.47645,0.646,H,A,0.23,0.4,21.796,21.796,77.62,HAA,-1.96733,0.221079,0.00950944,0.985955 beta-lactamase_156_T107M,beta-lactamase_156_107,TEM-1,beta-lactamase_156,P62593,0.985956,NO,107,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.117,-4.531,3.414,,,G,A,0.22,-0.06,0.341,,67.83,HPA,-1.265,0.111618,0.00239347,0.985956 beta-lactamase_39_T264I,beta-lactamase_39_264,TEM-1,beta-lactamase_39,P62593,0.985962,NO,264,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.0495842,0.0119399,0.985962 beta-lactamase_156_L136T,beta-lactamase_156_136,TEM-1,beta-lactamase_156,P62593,0.985963,NO,136,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.232,-3.487,2.255,,,H,A,0.55,-0.34,1.04,,48.95,HHH,-1.088,0.111618,0.00442304,0.985963 beta-lactamase_156_A183C,beta-lactamase_156_183,TEM-1,beta-lactamase_156,P62593,0.98597,NO,183,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.231,-4.684,3.453,,0.155,H,A,0.46,-0.91,23.859,23.859,77.62,HHH,-1.53367,0.111618,0.00296631,0.98597 beta-lactamase_625_G85K,beta-lactamase_625_85,TEM-1,beta-lactamase_625,P62593,0.985972,NO,85,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.011,-2.219,1.208,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.213352,0.00252173,0.985972 beta-lactamase_625_E102L,beta-lactamase_625_102,TEM-1,beta-lactamase_625,P62593,0.985973,NO,102,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.118,-3.618,1.5,,0.722,S,B,1.04,1.82,1.336,,73.08,HAH,-1.581,0.213352,0.00486633,0.985973 beta-lactamase_625_K254F,beta-lactamase_625_254,TEM-1,beta-lactamase_625,P62593,0.985976,NO,254,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.213352,0.00369,0.985976 beta-lactamase_K213C,beta-lactamase_213,TEM-1,beta-lactamase,P62593,0.985982,NO,213,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.81,-5.208,3.398,5.63167,0.67,,A,1.59,0.29,3.924,,67.83,ABH,-1.57767,0.221079,0.00610411,0.985982 beta-lactamase_156_G154T,beta-lactamase_156_154,TEM-1,beta-lactamase_156,P62593,0.985984,NO,154,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.823,-3.619,2.796,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.111618,0.00180205,0.985984 beta-lactamase_39_I125A,beta-lactamase_39_125,TEM-1,beta-lactamase_39,P62593,0.985984,NO,125,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.441,-3.138,1.697,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.0495842,0.00383964,0.985984 beta-lactamase_156_L197C,beta-lactamase_156_197,TEM-1,beta-lactamase_156,P62593,0.985987,NO,197,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.853,-4.635,3.782,,0.007,S,B,0.55,0.33,1.58,,60.14,HHP,-1.833,0.111618,0.00144602,0.985987 Pab1_D144A,Pab1_144,Pab1,Pab1,P04147,0.985995,NO,144,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.189,-3.116,1.927,,0.616,H,A,,0.6,,,,HAP,-1.40567,0.175299,0.00121131,0.985995 beta-lactamase_156_R273I,beta-lactamase_156_273,TEM-1,beta-lactamase_156,P62593,0.985997,NO,273,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.314,-4.08,1.766,,0.564,H,A,1.2,1.57,20.248,20.248,73.78,ABP,-1.841,0.111618,0.0077952,0.985997 beta-lactamase_156_L205A,beta-lactamase_156_205,TEM-1,beta-lactamase_156,P62593,0.985999,NO,205,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.922,-3.132,2.21,,,H,A,0.55,-0.46,0.678,,42.31,PHH,-1.57767,0.111618,0.00255802,0.985999 beta-lactamase_39_G281S,beta-lactamase_39_281,TEM-1,beta-lactamase_39,P62593,0.985999,NO,281,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-2.247,-3.28,1.033,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.0495842,0.0406482,0.985999 beta-lactamase_39_E175R,beta-lactamase_39_175,TEM-1,beta-lactamase_39,P62593,0.986002,NO,175,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.336,-3.064,0.728,,0.551,,A,1.04,1.05,3.676,,77.62,AAB,-1.31233,0.0495842,0.00482205,0.986002 beta-lactamase_39_L284Q,beta-lactamase_39_284,TEM-1,beta-lactamase_39,P62593,0.986003,NO,284,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.0495842,0.0686156,0.986003 beta-lactamase_156_M115S,beta-lactamase_156_115,TEM-1,beta-lactamase_156,P62593,0.986004,NO,115,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.389,-3.501,2.112,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.111618,0.0034337,0.986004 beta-lactamase_39_E35M,beta-lactamase_39_35,TEM-1,beta-lactamase_39,P62593,0.986007,NO,35,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-0.869,-4.754,3.885,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.0495842,0.00174441,0.986007 beta-lactamase_156_L218G,beta-lactamase_156_218,TEM-1,beta-lactamase_156,P62593,0.98601,NO,218,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.391,-3.644,2.253,,,I,b,0.55,-0.53,17.202,17.202,74.48,OHH,-1.58867,0.111618,0.00618274,0.98601 beta-lactamase_156_W288Y,beta-lactamase_156_288,TEM-1,beta-lactamase_156,P62593,0.986012,NO,288,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,,,,,,,,,,,,,BHO,,0.111618,,0.986012 beta-lactamase_156_E102V,beta-lactamase_156_102,TEM-1,beta-lactamase_156,P62593,0.986014,NO,102,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.118,-3.638,1.52,,0.722,S,B,1.04,1.82,15.721,15.721,73.08,HAH,-1.581,0.111618,0.00486633,0.986014 beta-lactamase_39_L199P,beta-lactamase_39_199,TEM-1,beta-lactamase_39,P62593,0.986019,NO,199,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-2.942,-2.099,-0.843,,0.832,H,A,0.55,0.42,15.504,15.504,77.62,PHH,-2.32933,0.0495842,0.0048649,0.986019 beta-lactamase_2500_E166F,beta-lactamase_2500_166,TEM-1,beta-lactamase_2500,P62593,0.986021,NO,166,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.756,-4.345,2.589,,0.508,G,A,1.04,1.05,2.124,,73.08,OAH,-1.42233,0.361275,0.00512989,0.986021 beta-lactamase_0_P60M,beta-lactamase_0_60,TEM-1,beta-lactamase_0,P62593,0.986023,NO,60,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-2.469,-4.701,2.232,,0.256,T,A,0.52,-0.56,3.653,,77.62,BOA,-1.97633,0.0500837,0.00521318,0.986023 beta-lactamase_39_V117A,beta-lactamase_39_117,TEM-1,beta-lactamase_39,P62593,0.986023,NO,117,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.53,-3.142,1.612,,,H,A,0.44,-0.34,1.182,,65.03,PHB,-1.741,0.0495842,0.00467906,0.986023 beta-lactamase_156_E195D,beta-lactamase_156_195,TEM-1,beta-lactamase_156,P62593,0.986026,NO,195,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.186,-1.979,-0.207,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.111618,0.00496565,0.986026 beta-lactamase_39_I229W,beta-lactamase_39_229,TEM-1,beta-lactamase_39,P62593,0.986026,NO,229,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.267,-5.365,4.098,,0.083,E,B,0.48,-0.76,1.114,,50,HHH,-1.58767,0.0495842,0.00477249,0.986026 beta-lactamase_39_S266T,beta-lactamase_39_266,TEM-1,beta-lactamase_39,P62593,0.986026,NO,266,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.0495842,0.0140785,0.986026 beta-lactamase_625_D113M,beta-lactamase_625_113,TEM-1,beta-lactamase_625,P62593,0.986026,NO,113,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.829,-4.826,2.997,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.213352,0.00474112,0.986026 kka2_1:2_R173C,kka2_1:2_173,Kka2,kka2_1:2,P00552,0.986029,NO,173,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.407,-5.224,2.817,,0.308,H,A,0.16,-0.13,15.389,15.389,65.53,HBH,-1.70533,0.295029,0.00784999,0.986029 beta-lactamase_156_P165A,beta-lactamase_156_165,TEM-1,beta-lactamase_156,P62593,0.986034,NO,165,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.373,-3.022,1.649,,0.203,T,A,0.52,-0.31,3.907,,73.78,AOA,-1.359,0.111618,0.00549538,0.986034 beta-lactamase_156_V214Q,beta-lactamase_156_214,TEM-1,beta-lactamase_156,P62593,0.986037,NO,214,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.299,-4.141,2.842,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.111618,0.00628442,0.986037 beta-lactamase_156_D113P,beta-lactamase_156_113,TEM-1,beta-lactamase_156,P62593,0.986046,NO,113,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.829,-3.062,1.233,,0.665,T,A,0.75,0.91,2.973,,73.08,PAO,-1.703,0.111618,0.00474112,0.986046 beta-lactamase_2500_M153L,beta-lactamase_2500_153,TEM-1,beta-lactamase_2500,P62593,0.986049,NO,153,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-3.193,-1.8,-1.393,,0.14,T,A,0.55,-0.11,3.409,,77.62,PHO,-2.25767,0.361275,0.00509109,0.986049 beta-lactamase_39_K144E,beta-lactamase_39_144,TEM-1,beta-lactamase_39,P62593,0.986049,NO,144,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-2.388,-2.372,-0.016,,0.863,H,A,2.34,1.27,14.556,14.556,77.62,OBA,-1.904,0.0495842,0.00481141,0.986049 beta-lactamase_625_R63K,beta-lactamase_625_63,TEM-1,beta-lactamase_625,P62593,0.986049,NO,63,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-0.943,-2.877,1.934,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.213352,0.00126938,0.986049 beta-lactamase_156_L218I,beta-lactamase_156_218,TEM-1,beta-lactamase_156,P62593,0.986051,NO,218,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.391,-3.447,2.056,,,I,b,0.55,-0.53,17.202,17.202,74.48,OHH,-1.58867,0.111618,0.00618274,0.986051 beta-lactamase_S281L,beta-lactamase_281,TEM-1,beta-lactamase,P62593,0.986051,NO,281,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.247,-2.187,-0.06,4.73591,0.128,H,A,0.25,-0.26,2.144,,77.62,HPH,-1.847,0.221079,0.0406482,0.986051 beta-lactamase_0_G76V,beta-lactamase_0_76,TEM-1,beta-lactamase_0,P62593,0.986052,NO,76,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.189,-3.485,2.296,,,H,A,0.29,-0.67,1.188,,67.83,OOH,-1.22267,0.0500837,0.00476637,0.986052 beta-lactamase_0_M153S,beta-lactamase_0_153,TEM-1,beta-lactamase_0,P62593,0.986054,NO,153,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-3.193,-2.433,-0.76,,0.14,T,A,0.55,-0.11,3.826,,77.62,PHO,-2.25767,0.0500837,0.00509109,0.986054 gb1_V247P,gb1_247,gb1,gb1,P06654,0.986057,NO,247,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.711,-3.702,1.991,,,,,,,0.805,,44.87,HHA,-1.485,0.177985,0.00435373,0.986057 beta-lactamase_156_P165E,beta-lactamase_156_165,TEM-1,beta-lactamase_156,P62593,0.98606,NO,165,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.373,-3.511,2.138,,0.203,T,A,0.52,-0.31,3.907,,73.78,AOA,-1.359,0.111618,0.00549538,0.98606 beta-lactamase_2500_A148S,beta-lactamase_2500_148,TEM-1,beta-lactamase_2500,P62593,0.98606,NO,148,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.757,-2.791,1.034,,0.379,H,A,0.46,-0.55,2.117,,72.73,PHH,-1.40167,0.361275,0.00547053,0.98606 beta-lactamase_39_L188V,beta-lactamase_39_188,TEM-1,beta-lactamase_39,P62593,0.98606,NO,188,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.166,-3.017,1.851,,,H,A,0.55,-0.3,2.982,,60.14,PHB,-1.47033,0.0495842,0.00295687,0.98606 PSD95pdz3_G344E,PSD95pdz3_344,PSD95pdz3,PSD95pdz3,P31016,0.98606,NO,344,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.008,-3.347,2.339,4.83855,,,,,14.06,,,,HOO,-1.10767,0.0758425,0.00078498,0.98606 beta-lactamase_0_G43Y,beta-lactamase_0_43,TEM-1,beta-lactamase_0,P62593,0.986066,NO,43,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.62,-4.387,3.767,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.0500837,0.00120151,0.986066 PSD95pdz3_G356K,PSD95pdz3_356,PSD95pdz3,PSD95pdz3,P31016,0.986069,NO,356,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.008,-3.364,2.356,4.8656,,,,,11.9575,,,,BOA,-1.22933,0.0758425,0.000623061,0.986069 beta-lactamase_625_H156R,beta-lactamase_625_156,TEM-1,beta-lactamase_625,P62593,0.986071,NO,156,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-3.156,-2.742,-0.414,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.213352,0.00468596,0.986071 beta-lactamase_39_L135M,beta-lactamase_39_135,TEM-1,beta-lactamase_39,P62593,0.98608,NO,135,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.002,-2.838,1.836,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.0495842,0.00244423,0.98608 beta-lactamase_156_R176W,beta-lactamase_156_176,TEM-1,beta-lactamase_156,P62593,0.986082,NO,176,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-0.863,-5.322,4.459,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.111618,0.00105554,0.986082 beta-lactamase_39_Q204A,beta-lactamase_39_204,TEM-1,beta-lactamase_39,P62593,0.986086,NO,204,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-1.382,-2.589,1.207,,0.204,H,A,0.64,0.09,0.489,,66.08,PPH,-1.49067,0.0495842,0.00364106,0.986086 beta-lactamase_156_L199S,beta-lactamase_156_199,TEM-1,beta-lactamase_156,P62593,0.98609,NO,199,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-2.942,-2.568,-0.374,,0.832,H,A,0.55,0.42,1.552,,77.62,PHH,-2.32933,0.111618,0.0048649,0.98609 Pab1_N187Y,Pab1_187,Pab1,Pab1,P04147,0.986093,NO,187,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-1.224,-4.083,2.859,,0.456,S,b,,1.87,,,,HPO,-1.272,0.175299,0.00083165,0.986093 beta-lactamase_L191L,beta-lactamase_191,TEM-1,beta-lactamase,P62593,0.986094,NO,191,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.087,-1.087,,5.72226,,H,A,1.07,0.09,1.23,,63.29,BHH,-1.445,0.221079,0.00263549,0.986094 beta-lactamase_2500_A200D,beta-lactamase_2500_200,TEM-1,beta-lactamase_2500,P62593,0.986107,NO,200,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.878,-2.929,1.051,,0.757,H,A,0.46,-0.19,0.436,,77.62,HHP,-2.001,0.361275,0.0060056,0.986107 beta-lactamase_156_L218A,beta-lactamase_156_218,TEM-1,beta-lactamase_156,P62593,0.986108,NO,218,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.391,-3.175,1.784,,,I,b,0.55,-0.53,17.202,17.202,74.48,OHH,-1.58867,0.111618,0.00618274,0.986108 beta-lactamase_S221H,beta-lactamase_221,TEM-1,beta-lactamase,P62593,0.986111,NO,221,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.754,-4.673,2.919,5.77407,0.624,H,A,0.74,-0.2,0.383,,74.48,BPH,-1.59967,0.221079,0.0046094,0.986111 beta-lactamase_0_K71W,beta-lactamase_0_71,TEM-1,beta-lactamase_0,P62593,0.986112,NO,71,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-0.8,-5.322,4.522,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.0500837,0.00103192,0.986112 beta-lactamase_625_A148K,beta-lactamase_625_148,TEM-1,beta-lactamase_625,P62593,0.986112,NO,148,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.757,-2.857,1.1,,0.379,H,A,0.46,-0.55,1.359,,72.73,PHH,-1.40167,0.213352,0.00547053,0.986112 beta-lactamase_39_E61S,beta-lactamase_39_61,TEM-1,beta-lactamase_39,P62593,0.986114,NO,61,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.115,-2.688,0.573,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.0495842,0.00440955,0.986114 beta-lactamase_39_G39Q,beta-lactamase_39_39,TEM-1,beta-lactamase_39,P62593,0.986116,NO,39,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.864,-2.885,1.021,,0.701,T,L,0.29,0.47,1.454,,77.62,HOH,-1.53633,0.0495842,0.00487611,0.986116 beta-lactamase_39_L135H,beta-lactamase_39_135,TEM-1,beta-lactamase_39,P62593,0.986118,NO,135,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.002,-4.934,3.932,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.0495842,0.00244423,0.986118 beta-lactamase_0_T186C,beta-lactamase_0_186,TEM-1,beta-lactamase_0,P62593,0.986119,NO,186,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.522,-5.021,2.499,,0.396,H,A,0.22,-0.28,16.606,16.606,77.62,HPP,-1.77633,0.0500837,0.00485034,0.986119 beta-lactamase_2500_D33K,beta-lactamase_2500_33,TEM-1,beta-lactamase_2500,P62593,0.986128,NO,33,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.321,-3.459,1.138,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.361275,0.00435556,0.986128 beta-lactamase_39_T139C,beta-lactamase_39_139,TEM-1,beta-lactamase_39,P62593,0.986129,NO,139,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.901,-4.964,3.063,,0.216,H,A,0.22,0.39,0.421,,77.62,PPH,-2.04667,0.0495842,0.00441837,0.986129 kka2_1:1_D33G,kka2_1:1_33,Kka2,kka2_1:1,P00552,0.986132,NO,33,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.186,-2.077,-0.109,,0.561,S,A,0.75,3.35,2.568,,71.59,PAH,-1.306,0.520039,0.00633568,0.986132 beta-lactamase_2500_L199Y,beta-lactamase_2500_199,TEM-1,beta-lactamase_2500,P62593,0.986142,NO,199,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-2.942,-4.431,1.489,,0.832,H,A,0.55,0.42,15.504,15.504,77.62,PHH,-2.32933,0.361275,0.0048649,0.986142 beta-lactamase_156_D33V,beta-lactamase_156_33,TEM-1,beta-lactamase_156,P62593,0.986145,NO,33,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.321,-3.488,1.167,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.111618,0.00435556,0.986145 beta-lactamase_K144C,beta-lactamase_144,TEM-1,beta-lactamase,P62593,0.986147,NO,144,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-2.388,-5.107,2.719,6.02507,0.863,H,A,2.81,1.27,0.515,,77.62,OBA,-1.904,0.221079,0.00481141,0.986147 beta-lactamase_156_V117Y,beta-lactamase_156_117,TEM-1,beta-lactamase_156,P62593,0.986176,NO,117,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.53,-2.958,1.428,,,H,A,0.44,-0.34,1.182,,65.03,PHB,-1.741,0.111618,0.00467906,0.986176 beta-lactamase_625_V101C,beta-lactamase_625_101,TEM-1,beta-lactamase_625,P62593,0.986185,NO,101,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.295,-4.837,3.542,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.213352,0.00374492,0.986185 beta-lactamase_156_A200Y,beta-lactamase_156_200,TEM-1,beta-lactamase_156,P62593,0.986189,NO,200,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.878,-4.399,2.521,,0.757,H,A,0.46,-0.19,16.368,16.368,77.62,HHP,-2.001,0.111618,0.0060056,0.986189 beta-lactamase_156_T186Q,beta-lactamase_156_186,TEM-1,beta-lactamase_156,P62593,0.986192,NO,186,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.522,-2.514,-0.008,,0.396,H,A,0.22,-0.28,16.606,16.606,77.62,HPP,-1.77633,0.111618,0.00485034,0.986192 beta-lactamase_2500_H94Y,beta-lactamase_2500_94,TEM-1,beta-lactamase_2500,P62593,0.986193,NO,94,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-2.5,-4.209,1.709,,0.776,,B,0.17,1.24,1.176,,77.62,HBH,-1.872,0.361275,0.00389226,0.986193 beta-lactamase_625_Y262F,beta-lactamase_625_262,TEM-1,beta-lactamase_625,P62593,0.986193,NO,262,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.213352,0.00853516,0.986193 beta-lactamase_S254V,beta-lactamase_254,TEM-1,beta-lactamase,P62593,0.986193,NO,254,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.126,-3.591,1.465,5.49575,0.312,,a,0.25,-0.48,24.91,24.91,69.58,OPB,-2.215,0.221079,0.00369,0.986193 beta-lactamase_39_H24L,beta-lactamase_39_24,TEM-1,beta-lactamase_39,P62593,0.986199,NO,24,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-2.481,-3.404,0.923,,,,,,,2.708,,93.01,OBO,-2.0035,0.0495842,0.00238894,0.986199 beta-lactamase_625_I206R,beta-lactamase_625_206,TEM-1,beta-lactamase_625,P62593,0.9862,NO,206,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-2.429,-3.125,0.696,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.213352,0.00528934,0.9862 beta-lactamase_156_Y103S,beta-lactamase_156_103,TEM-1,beta-lactamase_156,P62593,0.986204,NO,103,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-1.33,-3.594,2.264,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.111618,0.00443048,0.986204 beta-lactamase_39_G226I,beta-lactamase_39_226,TEM-1,beta-lactamase_39,P62593,0.986205,NO,226,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.461,-4.177,2.716,,0.701,T,l,0.29,-0.25,23.034,23.034,74.48,HOH,-1.42933,0.0495842,0.00665294,0.986205 beta-lactamase_A40A,beta-lactamase_40,TEM-1,beta-lactamase,P62593,0.986217,NO,40,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.402,-1.402,,4.9697,0.155,S,B,1.2,0.21,1.714,,73.78,OHB,-1.40267,0.221079,0.00490026,0.986217 beta-lactamase_625_K53E,beta-lactamase_625_53,TEM-1,beta-lactamase_625,P62593,0.986221,NO,53,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-2.313,-2.655,0.342,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.213352,0.00383383,0.986221 beta-lactamase_156_E119T,beta-lactamase_156_119,TEM-1,beta-lactamase_156,P62593,0.986228,NO,119,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.412,-3.526,2.114,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.111618,0.00386966,0.986228 beta-lactamase_156_W163A,beta-lactamase_156_163,TEM-1,beta-lactamase_156,P62593,0.986228,NO,163,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-1.843,-3.41,1.567,,0.467,,B,0.47,-0.5,15.095,15.095,63.99,BHA,-1.269,0.111618,0.00418955,0.986228 beta-lactamase_156_I45T,beta-lactamase_156_45,TEM-1,beta-lactamase_156,P62593,0.986232,NO,45,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-2.421,-2.537,0.116,,,E,B,0.48,-0.3,2.256,,77.62,HHA,-2.30267,0.111618,0.00452842,0.986232 beta-lactamase_156_E272C,beta-lactamase_156_272,TEM-1,beta-lactamase_156,P62593,0.986235,NO,272,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.111618,0.00545371,0.986235 beta-lactamase_625_Q267C,beta-lactamase_625_267,TEM-1,beta-lactamase_625,P62593,0.986237,NO,267,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.213352,0.0102128,0.986237 beta-lactamase_E56T,beta-lactamase_56,TEM-1,beta-lactamase,P62593,0.986237,NO,56,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.043,-2.013,-0.03,5.65281,0.198,E,B,0.52,0.31,2.022,,72.73,HAP,-1.94033,0.221079,0.00238534,0.986237 beta-lactamase_2500_E279Q,beta-lactamase_2500_279,TEM-1,beta-lactamase_2500,P62593,0.98624,NO,279,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.361275,0.0192826,0.98624 beta-lactamase_2500_K109E,beta-lactamase_2500_109,TEM-1,beta-lactamase_2500,P62593,0.98625,NO,109,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.734,-2.478,0.744,,0.787,G,A,2.34,2.21,0.998,,72.73,ABB,-1.63333,0.361275,0.00462493,0.98625 beta-lactamase_39_G52W,beta-lactamase_39_52,TEM-1,beta-lactamase_39,P62593,0.986252,NO,52,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.149,-5.364,4.215,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.0495842,0.00340138,0.986252 beta-lactamase_625_T263F,beta-lactamase_625_263,TEM-1,beta-lactamase_625,P62593,0.986257,NO,263,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.213352,0.0110582,0.986257 beta-lactamase_2500_L100M,beta-lactamase_2500_100,TEM-1,beta-lactamase_2500,P62593,0.986259,NO,100,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.218,-4.039,2.821,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.361275,0.00413885,0.986259 Pab1_I128L,Pab1_128,Pab1,Pab1,P04147,0.986261,NO,128,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.345,-2.419,1.074,,0.008,E,B,1.68,-0.6,1.706,,78.68,PHH,-1.231,0.175299,0.00104192,0.986261 beta-lactamase_2500_K144V,beta-lactamase_2500_144,TEM-1,beta-lactamase_2500,P62593,0.986269,NO,144,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-2.388,-3.003,0.615,,0.863,H,A,2.34,1.27,0.515,,77.62,OBA,-1.904,0.361275,0.00481141,0.986269 beta-lactamase_156_E169Q,beta-lactamase_156_169,TEM-1,beta-lactamase_156,P62593,0.98627,NO,169,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.23,-2.523,1.293,,0.337,,A,1.04,1,3.516,,73.08,PAH,-1.16533,0.111618,0.00400994,0.98627 beta-lactamase_2500_G39E,beta-lactamase_2500_39,TEM-1,beta-lactamase_2500,P62593,0.986277,NO,39,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.864,-2.833,0.969,,0.701,T,L,0.29,0.47,29.926,29.926,77.62,HOH,-1.53633,0.361275,0.00487611,0.986277 beta-lactamase_2500_H94V,beta-lactamase_2500_94,TEM-1,beta-lactamase_2500,P62593,0.986278,NO,94,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-2.5,-2.751,0.251,,0.776,,B,0.17,1.24,1.176,,77.62,HBH,-1.872,0.361275,0.00389226,0.986278 beta-lactamase_39_G281T,beta-lactamase_39_281,TEM-1,beta-lactamase_39,P62593,0.986278,NO,281,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.0495842,0.0406482,0.986278 beta-lactamase_E102T,beta-lactamase_102,TEM-1,beta-lactamase,P62593,0.986293,NO,102,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.118,-2.156,0.038,6.36157,0.722,S,B,1.5,1.82,1.336,,73.08,HAH,-1.581,0.221079,0.00486633,0.986293 beta-lactamase_T193L,beta-lactamase_193,TEM-1,beta-lactamase,P62593,0.986293,NO,193,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.914,-1.776,-0.138,5.67952,0.439,H,a,0.3,0.33,1.863,,63.99,HPO,-1.52133,0.221079,0.00482669,0.986293 beta-lactamase_39_S233W,beta-lactamase_39_233,TEM-1,beta-lactamase_39,P62593,0.986294,NO,233,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.886,-5.339,3.453,,0.016,E,B,0.27,-1.01,5.361,,77.62,BPO,-1.17267,0.0495842,0.00311415,0.986294 beta-lactamase_156_G154Y,beta-lactamase_156_154,TEM-1,beta-lactamase_156,P62593,0.986296,NO,154,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.823,-4.424,3.601,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.111618,0.00180205,0.986296 beta-lactamase_0_L223G,beta-lactamase_0_223,TEM-1,beta-lactamase_0,P62593,0.986302,NO,223,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.055,-3.765,2.71,,0.27,,B,0.55,0.09,1.633,,74.48,HHO,-1.35033,0.0500837,0.00372793,0.986302 beta-lactamase_156_H151E,beta-lactamase_156_151,TEM-1,beta-lactamase_156,P62593,0.986305,NO,151,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-2.96,-3.258,0.298,,0.594,H,A,0.17,0.1,1.401,,77.62,HBP,-2.34767,0.111618,0.00216946,0.986305 beta-lactamase_156_L47W,beta-lactamase_156_47,TEM-1,beta-lactamase_156,P62593,0.986325,NO,47,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.876,-5.24,3.364,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.111618,0.00439844,0.986325 hsp90_Q582Y,hsp90_582,hsp90,hsp90,P02829,0.986326,NO,582,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-3.278,-3.316,0,4.91603,0.453,S,B,,0.67,,,,OPH,-3.249,0.368192,0.000222939,0.986326 beta-lactamase_156_H151R,beta-lactamase_156_151,TEM-1,beta-lactamase_156,P62593,0.986329,NO,151,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-2.96,-1.217,-1.743,,0.594,H,A,0.17,0.1,1.401,,77.62,HBP,-2.34767,0.111618,0.00216946,0.986329 beta-lactamase_0_T116V,beta-lactamase_0_116,TEM-1,beta-lactamase_0,P62593,0.986339,NO,116,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.28,-3.415,2.135,,0.115,E,B,0.22,-0.12,1.356,,67.48,HPH,-1.39967,0.0500837,0.00336175,0.986339 Pab1_N162R,Pab1_162,Pab1,Pab1,P04147,0.986339,NO,162,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-2.313,-3.757,1.444,,0.681,T,A,,1.12,,,,APO,-1.532,0.175299,0.0030719,0.986339 beta-lactamase_156_Q204E,beta-lactamase_156_204,TEM-1,beta-lactamase_156,P62593,0.986343,NO,204,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-1.382,-3.106,1.724,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.111618,0.00364106,0.986343 beta-lactamase_625_P25D,beta-lactamase_625_25,TEM-1,beta-lactamase_625,P62593,0.986347,NO,25,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.526,-2.562,1.036,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.213352,0.00347571,0.986347 kka2_1:8_A255P,kka2_1:8_255,Kka2,kka2_1:8,P00552,0.986347,NO,255,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.715,-3.184,1.469,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.100394,0.0126809,0.986347 kka2_1:8_A255P,kka2_1:8_255,Kka2,kka2_1:8,P00552,0.986347,NO,255,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.715,-3.184,1.469,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.100394,0.0126809,0.986347 beta-lactamase_39_H24G,beta-lactamase_39_24,TEM-1,beta-lactamase_39,P62593,0.986355,NO,24,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-2.481,-2.499,0.018,,,,,,,2.708,,93.01,OBO,-2.0035,0.0495842,0.00238894,0.986355 kka2_1:2_E3G,kka2_1:2_3,Kka2,kka2_1:2,P00552,0.986355,NO,3,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.199,-2.062,-0.137,,,,,,,7.22,,92.05,HAP,-2.11567,0.295029,0.00267607,0.986355 beta-lactamase_156_L120V,beta-lactamase_156_120,TEM-1,beta-lactamase_156,P62593,0.98636,NO,120,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.044,-3.031,1.987,,,H,A,0.55,-1.13,7.813,,64.69,AHO,-1.13633,0.111618,0.00143563,0.98636 beta-lactamase_156_K254E,beta-lactamase_156_254,TEM-1,beta-lactamase_156,P62593,0.986361,NO,254,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.111618,0.00369,0.986361 beta-lactamase_2500_Y262L,beta-lactamase_2500_262,TEM-1,beta-lactamase_2500,P62593,0.986361,NO,262,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.361275,0.00853516,0.986361 beta-lactamase_39_L38A,beta-lactamase_39_38,TEM-1,beta-lactamase_39,P62593,0.986362,NO,38,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.343,-3.151,1.808,,0.088,H,A,0.55,0.2,17.089,17.089,64.34,PHO,-1.78033,0.0495842,0.00373244,0.986362 beta-lactamase_156_N152G,beta-lactamase_156_152,TEM-1,beta-lactamase_156,P62593,0.986365,NO,152,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-2.757,-2.26,-0.497,,0.863,H,A,0.61,0.92,4.038,,77.62,BPH,-2.97,0.111618,0.00471429,0.986365 beta-lactamase_156_E46G,beta-lactamase_156_46,TEM-1,beta-lactamase_156,P62593,0.986366,NO,46,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.94,-2.778,0.838,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.111618,0.00427568,0.986366 beta-lactamase_2500_A77V,beta-lactamase_2500_77,TEM-1,beta-lactamase_2500,P62593,0.986367,NO,77,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.234,-2.654,1.42,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.361275,0.00282362,0.986367 beta-lactamase_39_K144V,beta-lactamase_39_144,TEM-1,beta-lactamase_39,P62593,0.986374,NO,144,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-2.388,-3.003,0.615,,0.863,H,A,2.34,1.27,14.556,14.556,77.62,OBA,-1.904,0.0495842,0.00481141,0.986374 Pab1_G167A,Pab1_167,Pab1,Pab1,P04147,0.986379,NO,167,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.223,-2.821,1.598,,0.195,S,g,,0.03,,,,BOH,-1.25133,0.175299,0.00146449,0.986379 beta-lactamase_156_N168Q,beta-lactamase_156_168,TEM-1,beta-lactamase_156,P62593,0.986393,NO,168,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-1.029,-3.749,2.72,,0.113,G,A,0.61,-0.4,1.014,,44.41,HPA,-1.13233,0.111618,0.00288667,0.986393 beta-lactamase_156_A133T,beta-lactamase_156_133,TEM-1,beta-lactamase_156,P62593,0.986394,NO,133,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.186,-2.382,1.196,,,H,A,0.46,-0.86,0.805,,67.83,HHP,-0.988333,0.111618,0.00468022,0.986394 beta-lactamase_625_R41T,beta-lactamase_625_41,TEM-1,beta-lactamase_625,P62593,0.986394,NO,41,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-0.942,-3.385,2.443,,0.321,E,B,1.2,-0.07,1.186,,65.03,HBH,-1.30267,0.213352,0.00123327,0.986394 beta-lactamase_39_L223C,beta-lactamase_39_223,TEM-1,beta-lactamase_39,P62593,0.986396,NO,223,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.055,-4.721,3.666,,0.27,,B,0.55,0.09,1.511,,74.48,HHO,-1.35033,0.0495842,0.00372793,0.986396 beta-lactamase_625_H156V,beta-lactamase_625_156,TEM-1,beta-lactamase_625,P62593,0.986398,NO,156,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-3.156,-3.735,0.579,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.213352,0.00468596,0.986398 beta-lactamase_39_L248V,beta-lactamase_39_248,TEM-1,beta-lactamase_39,P62593,0.986399,NO,248,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.0495842,0.00428493,0.986399 beta-lactamase_A182H,beta-lactamase_182,TEM-1,beta-lactamase,P62593,0.9864,NO,182,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.777,-3.358,1.581,4.98609,0.136,H,A,0.52,-0.66,2.032,,93.01,OHH,-1.27367,0.221079,0.00559099,0.9864 beta-lactamase_L10V,beta-lactamase_10,TEM-1,beta-lactamase,P62593,0.9864,NO,10,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.623,-2.123,0.5,,,,,,,2.467,,65.38,HHH,-1.83833,0.221079,0.00296968,0.9864 beta-lactamase_625_T147A,beta-lactamase_625_147,TEM-1,beta-lactamase_625,P62593,0.986401,NO,147,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.149,-2.982,1.833,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.213352,0.00226017,0.986401 beta-lactamase_625_T107S,beta-lactamase_625_107,TEM-1,beta-lactamase_625,P62593,0.986403,NO,107,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.117,-1.871,0.754,,,G,A,0.22,-0.06,3.676,,67.83,HPA,-1.265,0.213352,0.00239347,0.986403 beta-lactamase_156_Q88I,beta-lactamase_156_88,TEM-1,beta-lactamase_156,P62593,0.98641,NO,88,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.086,-3.166,1.08,,0.807,,B,0.64,2.03,0.911,,77.62,APH,-1.53433,0.111618,0.00504167,0.98641 beta-lactamase_156_G226N,beta-lactamase_156_226,TEM-1,beta-lactamase_156,P62593,0.986417,NO,226,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.461,-2.628,1.167,,0.701,T,l,0.29,-0.25,3.199,,74.48,HOH,-1.42933,0.111618,0.00665294,0.986417 PSD95pdz3_N381H,PSD95pdz3_381,PSD95pdz3,PSD95pdz3,P31016,0.986421,NO,381,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-1.41,-3.687,2.277,5.66057,,,,,28.2162,,,,BPH,-1.37767,0.0758425,0.000265374,0.986421 beta-lactamase_E166R,beta-lactamase_166,TEM-1,beta-lactamase,P62593,0.986422,NO,166,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.756,-3.805,2.049,5.60527,0.508,G,A,0.52,1.05,2.124,,73.08,OAH,-1.42233,0.221079,0.00512989,0.986422 beta-lactamase_156_P250M,beta-lactamase_156_250,TEM-1,beta-lactamase_156,P62593,0.98643,NO,250,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.111618,0.00550899,0.98643 beta-lactamase_156_W163V,beta-lactamase_156_163,TEM-1,beta-lactamase_156,P62593,0.986431,NO,163,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-1.843,-3.617,1.774,,0.467,,B,0.47,-0.5,15.095,15.095,63.99,BHA,-1.269,0.111618,0.00418955,0.986431 beta-lactamase_39_V31A,beta-lactamase_39_31,TEM-1,beta-lactamase_39,P62593,0.986431,NO,31,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.822,-2.265,0.443,,,H,A,0.44,-0.46,2.885,,73.78,BHB,-2.03767,0.0495842,0.00478065,0.986431 beta-lactamase_39_L49Q,beta-lactamase_39_49,TEM-1,beta-lactamase_39,P62593,0.986433,NO,49,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.897,-2.823,0.926,,0.131,T,A,0.55,0.04,13.838,13.838,64.69,AHP,-1.99233,0.0495842,0.00401477,0.986433 beta-lactamase_625_H156A,beta-lactamase_625_156,TEM-1,beta-lactamase_625,P62593,0.986435,NO,156,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-3.156,-2.83,-0.326,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.213352,0.00468596,0.986435 beta-lactamase_625_L248M,beta-lactamase_625_248,TEM-1,beta-lactamase_625,P62593,0.986436,NO,248,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.213352,0.00428493,0.986436 beta-lactamase_2500_A183N,beta-lactamase_2500_183,TEM-1,beta-lactamase_2500,P62593,0.98644,NO,183,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.231,-2.504,1.273,,0.155,H,A,0.46,-0.91,12.189,,77.62,HHH,-1.53367,0.361275,0.00296631,0.98644 beta-lactamase_P172S,beta-lactamase_172,TEM-1,beta-lactamase,P62593,0.986447,NO,172,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.998,-2.394,1.396,5.98941,0.639,T,b,1.1,0.24,2.087,,74.48,HOP,-2.03067,0.221079,0.00312594,0.986447 beta-lactamase_156_L47K,beta-lactamase_156_47,TEM-1,beta-lactamase_156,P62593,0.98645,NO,47,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.876,-3.656,1.78,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.111618,0.00439844,0.98645 beta-lactamase_156_E175T,beta-lactamase_156_175,TEM-1,beta-lactamase_156,P62593,0.986461,NO,175,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.336,-3.551,1.215,,0.551,,A,1.04,1.05,2.334,,77.62,AAB,-1.31233,0.111618,0.00482205,0.986461 beta-lactamase_39_V72I,beta-lactamase_39_72,TEM-1,beta-lactamase_39,P62593,0.986477,NO,72,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.658,-3.311,1.653,,,H,A,0.44,-1.03,1.92,,65.73,BHH,-1.32167,0.0495842,0.00501194,0.986477 beta-lactamase_156_W227F,beta-lactamase_156_227,TEM-1,beta-lactamase_156,P62593,0.98648,NO,227,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-0.982,-2.609,1.627,,0.272,,B,0.47,-0.29,2.533,,74.48,OHH,-1.595,0.111618,0.00226019,0.98648 beta-lactamase_Q86R,beta-lactamase_86,TEM-1,beta-lactamase,P62593,0.98648,NO,86,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.4,-2.686,0.286,5.39897,0.696,S,A,0.12,2.38,2.105,,77.62,OPA,-1.61067,0.221079,0.00450027,0.98648 beta-lactamase_156_L49F,beta-lactamase_156_49,TEM-1,beta-lactamase_156,P62593,0.986486,NO,49,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.897,-3.092,1.195,,0.131,T,A,0.55,0.04,3.112,,64.69,AHP,-1.99233,0.111618,0.00401477,0.986486 beta-lactamase_2500_E102Q,beta-lactamase_2500_102,TEM-1,beta-lactamase_2500,P62593,0.986488,NO,102,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.118,-3.043,0.925,,0.722,S,B,1.04,1.82,1.336,,73.08,HAH,-1.581,0.361275,0.00486633,0.986488 beta-lactamase_156_D207K,beta-lactamase_156_207,TEM-1,beta-lactamase_156,P62593,0.986489,NO,207,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.064,-2.897,0.833,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.111618,0.00592942,0.986489 beta-lactamase_156_M153T,beta-lactamase_156_153,TEM-1,beta-lactamase_156,P62593,0.986489,NO,153,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-3.193,-2.237,-0.956,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.111618,0.00509109,0.986489 beta-lactamase_0_D129C,beta-lactamase_0_129,TEM-1,beta-lactamase_0,P62593,0.986494,NO,129,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.816,-5.136,4.32,,,,B,0.75,-0.69,2.66,,34.97,PAP,-0.818,0.0500837,0.00109178,0.986494 beta-lactamase_39_L160I,beta-lactamase_39_160,TEM-1,beta-lactamase_39,P62593,0.986498,NO,160,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.977,-2.155,1.178,,0.022,,B,0.55,-0.6,0.895,,44.41,BHA,-0.936,0.0495842,0.00193775,0.986498 beta-lactamase_156_N168A,beta-lactamase_156_168,TEM-1,beta-lactamase_156,P62593,0.986502,NO,168,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-1.029,-3.17,2.141,,0.113,G,A,0.61,-0.4,1.014,,44.41,HPA,-1.13233,0.111618,0.00288667,0.986502 Pab1_I157L,Pab1_157,Pab1,Pab1,P04147,0.986502,NO,157,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.623,-2.465,0.842,,,,,,,1.439,,79.72,BHH,-1.28667,0.175299,0.0018103,0.986502 beta-lactamase_2500_Q267C,beta-lactamase_2500_267,TEM-1,beta-lactamase_2500,P62593,0.986505,NO,267,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.361275,0.0102128,0.986505 beta-lactamase_156_G265F,beta-lactamase_156_265,TEM-1,beta-lactamase_156,P62593,0.986508,NO,265,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.111618,0.00811926,0.986508 Pab1_G177C,Pab1_177,Pab1,Pab1,P04147,0.986534,NO,177,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-2.24,-4.881,2.641,,,,,,,,,,AOH,-1.94067,0.175299,0.00170727,0.986534 beta-lactamase_156_A247Y,beta-lactamase_156_247,TEM-1,beta-lactamase_156,P62593,0.986535,NO,247,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.111618,0.00611275,0.986535 beta-lactamase_156_T147C,beta-lactamase_156_147,TEM-1,beta-lactamase_156,P62593,0.986538,NO,147,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.149,-4.804,3.655,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.111618,0.00226017,0.986538 beta-lactamase_156_K213A,beta-lactamase_156_213,TEM-1,beta-lactamase_156,P62593,0.98654,NO,213,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.81,-3.194,1.384,,0.67,,A,2.34,0.29,3.924,,67.83,ABH,-1.57767,0.111618,0.00610411,0.98654 beta-lactamase_A16Q,beta-lactamase_16,TEM-1,beta-lactamase,P62593,0.986543,NO,16,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,,-4.028,2.093,,,,,,,,,,HHH,,0.221079,0.00245392,0.986543 beta-lactamase_A222M,beta-lactamase_222,TEM-1,beta-lactamase,P62593,0.986543,NO,222,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.103,-4.656,2.553,5.2262,0.233,H,A,0.47,-0.25,0.379,,77.62,PHH,-1.63733,0.221079,0.00466094,0.986543 beta-lactamase_M153T,beta-lactamase_153,TEM-1,beta-lactamase,P62593,0.986543,NO,153,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-3.193,-2.237,-0.956,5.46509,0.14,T,A,1.07,-0.11,2.061,,77.62,PHO,-2.25767,0.221079,0.00509109,0.986543 beta-lactamase_S281N,beta-lactamase_281,TEM-1,beta-lactamase,P62593,0.986543,NO,281,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.247,-3.874,1.627,4.73591,0.128,H,A,0.25,-0.26,2.144,,77.62,HPH,-1.847,0.221079,0.0406482,0.986543 beta-lactamase_2500_D252Y,beta-lactamase_2500_252,TEM-1,beta-lactamase_2500,P62593,0.986555,NO,252,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.94,,,,0.766,,B,1.59,1.16,,,67.83,OAO,-2.0965,0.361275,0.00575769,0.986555 beta-lactamase_156_P224L,beta-lactamase_156_224,TEM-1,beta-lactamase_156,P62593,0.986557,NO,224,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.893,-3.582,2.689,,0.383,,B,0.52,-0.3,0.383,,74.48,HOH,-1.26433,0.111618,0.00189564,0.986557 beta-lactamase_39_D99N,beta-lactamase_39_99,TEM-1,beta-lactamase_39,P62593,0.986557,NO,99,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.191,-3.466,2.275,,0.402,G,A,0.75,0.36,0.374,,64.69,PAH,-1.794,0.0495842,0.00305446,0.986557 beta-lactamase_625_T126V,beta-lactamase_625_126,TEM-1,beta-lactamase_625,P62593,0.98656,NO,126,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.122,-3.336,2.214,,0.05,H,A,0.22,-0.05,0.817,,44.41,HPH,-1.60467,0.213352,0.00244552,0.98656 beta-lactamase_E166G,beta-lactamase_166,TEM-1,beta-lactamase,P62593,0.98656,NO,166,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.756,-2.741,0.985,5.60527,0.508,G,A,0.52,1.05,2.124,,73.08,OAH,-1.42233,0.221079,0.00512989,0.98656 beta-lactamase_156_G265E,beta-lactamase_156_265,TEM-1,beta-lactamase_156,P62593,0.986564,NO,265,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.111618,0.00811926,0.986564 beta-lactamase_39_T264A,beta-lactamase_39_264,TEM-1,beta-lactamase_39,P62593,0.986565,NO,264,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.0495842,0.0119399,0.986565 beta-lactamase_625_A268Y,beta-lactamase_625_268,TEM-1,beta-lactamase_625,P62593,0.986566,NO,268,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.213352,0.0102525,0.986566 gb1_T244F,gb1_244,gb1,gb1,P06654,0.986583,NO,244,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.637,-3.759,2.122,,,,,,,0.202,,11.83,PPA,-1.92567,0.177985,0.00222755,0.986583 beta-lactamase_625_V157A,beta-lactamase_625_157,TEM-1,beta-lactamase_625,P62593,0.986587,NO,157,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.751,-2.656,0.905,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.213352,0.00506849,0.986587 beta-lactamase_156_L120I,beta-lactamase_156_120,TEM-1,beta-lactamase_156,P62593,0.986591,NO,120,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.044,-2.541,1.497,,,H,A,0.55,-1.13,7.813,,64.69,AHO,-1.13633,0.111618,0.00143563,0.986591 beta-lactamase_T187S,beta-lactamase_187,TEM-1,beta-lactamase,P62593,0.986591,NO,187,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.401,-2.134,0.733,5.11453,0.007,H,A,0.3,-1.19,1.751,,67.48,PPH,-1.69633,0.221079,0.00491782,0.986591 beta-lactamase_625_L192W,beta-lactamase_625_192,TEM-1,beta-lactamase_625,P62593,0.986592,NO,192,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.254,-5.176,3.922,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.213352,0.00558728,0.986592 beta-lactamase_156_Q86E,beta-lactamase_156_86,TEM-1,beta-lactamase_156,P62593,0.986594,NO,86,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.4,-2.379,-0.021,,0.696,S,A,0.64,2.38,27.704,27.704,77.62,OPA,-1.61067,0.111618,0.00450027,0.986594 beta-lactamase_39_A268G,beta-lactamase_39_268,TEM-1,beta-lactamase_39,P62593,0.986608,NO,268,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.0495842,0.0102525,0.986608 beta-lactamase_156_P105S,beta-lactamase_156_105,TEM-1,beta-lactamase_156,P62593,0.986614,NO,105,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.813,-2.526,1.713,,0.226,T,A,0.52,0.8,1.154,,63.29,POH,-1.01533,0.111618,0.0011981,0.986614 beta-lactamase_K53Q,beta-lactamase_53,TEM-1,beta-lactamase,P62593,0.986616,NO,53,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-2.313,-2.642,0.329,5.93654,0.589,,B,1.82,1.15,19.72,19.72,77.62,OBH,-2.1,0.221079,0.00383383,0.986616 beta-lactamase_39_V31N,beta-lactamase_39_31,TEM-1,beta-lactamase_39,P62593,0.986617,NO,31,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.822,-4.194,2.372,,,H,A,0.44,-0.46,2.885,,73.78,BHB,-2.03767,0.0495842,0.00478065,0.986617 beta-lactamase_625_P105E,beta-lactamase_625_105,TEM-1,beta-lactamase_625,P62593,0.986623,NO,105,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.813,-3.437,2.624,,0.226,T,A,0.52,0.8,1.154,,63.29,POH,-1.01533,0.213352,0.0011981,0.986623 beta-lactamase_39_G281W,beta-lactamase_39_281,TEM-1,beta-lactamase_39,P62593,0.986627,NO,281,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.0495842,0.0406482,0.986627 beta-lactamase_625_S256H,beta-lactamase_625_256,TEM-1,beta-lactamase_625,P62593,0.986628,NO,256,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.213352,0.00710634,0.986628 beta-lactamase_39_G90F,beta-lactamase_39_90,TEM-1,beta-lactamase_39,P62593,0.986629,NO,90,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-2.091,-4.407,2.316,,0.598,T,A,0.29,0.32,30.794,30.794,77.62,HOB,-1.52633,0.0495842,0.00490273,0.986629 beta-lactamase_0_L160P,beta-lactamase_0_160,TEM-1,beta-lactamase_0,P62593,0.986632,NO,160,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.977,-4.121,3.144,,0.022,,B,0.55,-0.6,0.68,,44.41,BHA,-0.936,0.0500837,0.00193775,0.986632 beta-lactamase_0_K213T,beta-lactamase_0_213,TEM-1,beta-lactamase_0,P62593,0.986635,NO,213,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.81,-2.431,0.621,,0.67,,A,2.34,0.29,3.015,,67.83,ABH,-1.57767,0.0500837,0.00610411,0.986635 beta-lactamase_156_L89E,beta-lactamase_156_89,TEM-1,beta-lactamase_156,P62593,0.986637,NO,89,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.096,-3.801,2.705,,0.168,T,A,0.55,0.63,2.633,,64.34,PHO,-1.75767,0.111618,0.00207068,0.986637 kka2_1:8_D118N,kka2_1:8_118,Kka2,kka2_1:8,P00552,0.986638,NO,118,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.07,-3.163,1.093,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.100394,0.0067852,0.986638 kka2_1:8_D118N,kka2_1:8_118,Kka2,kka2_1:8,P00552,0.986638,NO,118,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.07,-3.163,1.093,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.100394,0.0067852,0.986638 beta-lactamase_156_V214N,beta-lactamase_156_214,TEM-1,beta-lactamase_156,P62593,0.986641,NO,214,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.299,-3.962,2.663,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.111618,0.00628442,0.986641 beta-lactamase_625_L205M,beta-lactamase_625_205,TEM-1,beta-lactamase_625,P62593,0.986641,NO,205,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.922,-3.889,2.967,,,H,A,0.55,-0.46,3.782,,42.31,PHH,-1.57767,0.213352,0.00255802,0.986641 beta-lactamase_156_M115I,beta-lactamase_156_115,TEM-1,beta-lactamase_156,P62593,0.986654,NO,115,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.389,-3.258,1.869,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.111618,0.0034337,0.986654 beta-lactamase_625_Q276L,beta-lactamase_625_276,TEM-1,beta-lactamase_625,P62593,0.986654,NO,276,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.213352,0.0191712,0.986654 beta-lactamase_625_G90S,beta-lactamase_625_90,TEM-1,beta-lactamase_625,P62593,0.986655,NO,90,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-2.091,-2.198,0.107,,0.598,T,A,0.29,0.32,0.319,,77.62,HOB,-1.52633,0.213352,0.00490273,0.986655 beta-lactamase_2500_A77H,beta-lactamase_2500_77,TEM-1,beta-lactamase_2500,P62593,0.986657,NO,77,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.234,-3.165,1.931,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.361275,0.00282362,0.986657 beta-lactamase_625_N98A,beta-lactamase_625_98,TEM-1,beta-lactamase_625,P62593,0.986657,NO,98,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-2.973,-2.132,-0.841,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.213352,0.00505389,0.986657 beta-lactamase_625_A40Q,beta-lactamase_625_40,TEM-1,beta-lactamase_625,P62593,0.986658,NO,40,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.402,-4.1,2.698,,0.155,S,B,0.46,0.21,1.357,,73.78,OHB,-1.40267,0.213352,0.00490026,0.986658 kka2_1:2_Q136K,kka2_1:2_136,Kka2,kka2_1:2,P00552,0.986659,NO,136,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-3.021,-3.273,0.252,,0.331,,b,0.4,0.96,2.726,,92.05,BPH,-2.16933,0.295029,0.00624149,0.986659 beta-lactamase_39_R92W,beta-lactamase_39_92,TEM-1,beta-lactamase_39,P62593,0.98666,NO,92,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.718,-5.477,3.759,,0.479,E,B,1.2,1.36,0.389,,65.38,BBH,-1.50367,0.0495842,0.00429626,0.98666 Pab1_K164N,Pab1_164,Pab1,Pab1,P04147,0.986664,NO,164,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-2.298,-1.99,-0.308,,,,,,,,,,OBP,-1.41767,0.175299,0.00255241,0.986664 beta-lactamase_156_L49M,beta-lactamase_156_49,TEM-1,beta-lactamase_156,P62593,0.986666,NO,49,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.897,-4.411,2.514,,0.131,T,A,0.55,0.04,3.112,,64.69,AHP,-1.99233,0.111618,0.00401477,0.986666 beta-lactamase_625_R257K,beta-lactamase_625_257,TEM-1,beta-lactamase_625,P62593,0.986669,NO,257,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.213352,0.00756629,0.986669 beta-lactamase_D113K,beta-lactamase_113,TEM-1,beta-lactamase,P62593,0.986671,NO,113,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.829,-2.696,0.867,6.04499,0.665,T,A,0.23,0.91,21.104,21.104,73.08,PAO,-1.703,0.221079,0.00474112,0.986671 beta-lactamase_G90H,beta-lactamase_90,TEM-1,beta-lactamase,P62593,0.986671,NO,90,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-2.091,-3.353,1.262,5.51991,0.598,T,A,0.23,0.32,1.791,,77.62,HOB,-1.52633,0.221079,0.00490273,0.986671 beta-lactamase_S281C,beta-lactamase_281,TEM-1,beta-lactamase,P62593,0.986671,NO,281,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.247,-4.664,2.417,4.73591,0.128,H,A,0.25,-0.26,2.144,,77.62,HPH,-1.847,0.221079,0.0406482,0.986671 beta-lactamase_S96W,beta-lactamase_96,TEM-1,beta-lactamase,P62593,0.986671,NO,96,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.27,-5.497,3.227,5.29889,0.368,,b,0.25,0.39,32.348,32.348,73.78,HPP,-2.019,0.221079,0.00551835,0.986671 beta-lactamase_156_W227Y,beta-lactamase_156_227,TEM-1,beta-lactamase_156,P62593,0.986679,NO,227,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-0.982,-3.356,2.374,,0.272,,B,0.47,-0.29,2.533,,74.48,OHH,-1.595,0.111618,0.00226019,0.986679 beta-lactamase_625_D161S,beta-lactamase_625_161,TEM-1,beta-lactamase_625,P62593,0.986683,NO,161,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.891,-2.488,1.597,,0.341,,A,0.75,-0.52,4.655,,61.19,HAB,-0.961333,0.213352,0.000897697,0.986683 beta-lactamase_625_F149N,beta-lactamase_625_149,TEM-1,beta-lactamase_625,P62593,0.986688,NO,149,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.299,-4.055,2.756,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.213352,0.00418462,0.986688 beta-lactamase_39_K286T,beta-lactamase_39_286,TEM-1,beta-lactamase_39,P62593,0.986691,NO,286,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.0495842,,0.986691 beta-lactamase_0_A222W,beta-lactamase_0_222,TEM-1,beta-lactamase_0,P62593,0.986696,NO,222,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.103,-5.409,3.306,,0.233,H,A,0.46,-0.25,2.015,,77.62,PHH,-1.63733,0.0500837,0.00466094,0.986696 beta-lactamase_156_K254T,beta-lactamase_156_254,TEM-1,beta-lactamase_156,P62593,0.986699,NO,254,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.111618,0.00369,0.986699 beta-lactamase_39_E272P,beta-lactamase_39_272,TEM-1,beta-lactamase_39,P62593,0.9867,NO,272,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.127,,,,0.081,H,A,0.43,-0.97,12.983,12.983,63.64,AAB,-1.56333,0.0495842,0.00545371,0.9867 beta-lactamase_K190V,beta-lactamase_190,TEM-1,beta-lactamase,P62593,0.986701,NO,190,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.994,-2.992,0.998,5.49163,0.371,H,A,1.82,0.16,29.753,29.753,77.62,BBH,-1.64167,0.221079,0.00574527,0.986701 beta-lactamase_39_R159K,beta-lactamase_39_159,TEM-1,beta-lactamase_39,P62593,0.986702,NO,159,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-0.94,-2.865,1.925,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.0495842,0.00108472,0.986702 beta-lactamase_625_A170L,beta-lactamase_625_170,TEM-1,beta-lactamase_625,P62593,0.986709,NO,170,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.237,-3.289,2.052,,0.126,,L,0.46,-0.35,3.626,,64.69,AHH,-1.63267,0.213352,0.00431903,0.986709 beta-lactamase_156_I45V,beta-lactamase_156_45,TEM-1,beta-lactamase_156,P62593,0.986717,NO,45,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-2.421,-2.178,-0.243,,,E,B,0.48,-0.3,2.256,,77.62,HHA,-2.30267,0.111618,0.00452842,0.986717 beta-lactamase_39_T264C,beta-lactamase_39_264,TEM-1,beta-lactamase_39,P62593,0.986718,NO,264,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.0495842,0.0119399,0.986718 beta-lactamase_S80N,beta-lactamase_80,TEM-1,beta-lactamase,P62593,0.986726,NO,80,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.029,-2.999,0.97,5.23748,0.192,H,A,0.25,0.46,2.256,,77.62,HPB,-1.44567,0.221079,0.00565569,0.986726 beta-lactamase_156_S51C,beta-lactamase_156_51,TEM-1,beta-lactamase_156,P62593,0.986727,NO,51,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.526,-4.878,3.352,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.111618,0.00504821,0.986727 beta-lactamase_156_M180W,beta-lactamase_156_180,TEM-1,beta-lactamase_156,P62593,0.98673,NO,180,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-2.795,-5.124,2.329,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.111618,0.00552048,0.98673 beta-lactamase_39_H156N,beta-lactamase_39_156,TEM-1,beta-lactamase_39,P62593,0.986731,NO,156,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-3.156,-2.52,-0.636,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.0495842,0.00468596,0.986731 E1_Ubiquitin_A46Y,E1_Ubiquitin_46,Uba1,E1_Ubiquitin,P0CG63,0.986737,NO,46,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.367,-4.103,2.736,,0.398,T,L,,-0.8,,,,HHO,-1.17167,0.18783,0.004233,0.986737 E1_Ubiquitin_F45D,E1_Ubiquitin_45,Uba1,E1_Ubiquitin,P0CG63,0.986737,NO,45,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.149,-3.736,2.587,,0.26,E,B,,-0.99,,,,HHH,-1.316,0.18783,0.00193245,0.986737 E1_Ubiquitin_G76G,E1_Ubiquitin_76,Uba1,E1_Ubiquitin,P0CG63,0.986737,NO,76,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.999,-0.999,,,0.23,,B,0.75,0.08,1.702,,83.73,OOO,-0.999,0.18783,0.00125575,0.986737 E1_Ubiquitin_H70T,E1_Ubiquitin_70,Uba1,E1_Ubiquitin,P0CG63,0.986737,NO,70,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-1.36,,,,0.05,E,B,0.61,-0.97,,,93.18,HBH,-1.146,0.18783,0.00206914,0.986737 E1_Ubiquitin_K48R,E1_Ubiquitin_48,Uba1,E1_Ubiquitin,P0CG63,0.986737,NO,48,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.219,-2.996,1.777,,0.132,E,B,,-0.28,,,,OBO,-1.109,0.18783,0.00100363,0.986737 beta-lactamase_0_L74S,beta-lactamase_0_74,TEM-1,beta-lactamase_0,P62593,0.986738,NO,74,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.296,-3.399,2.103,,,H,A,0.55,-0.91,1.46,,50,HHO,-1.34933,0.0500837,0.00493255,0.986738 beta-lactamase_2500_R92L,beta-lactamase_2500_92,TEM-1,beta-lactamase_2500,P62593,0.98674,NO,92,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.718,-2.788,1.07,,0.479,E,B,1.2,1.36,3.069,,65.38,BBH,-1.50367,0.361275,0.00429626,0.98674 beta-lactamase_39_N50P,beta-lactamase_39_50,TEM-1,beta-lactamase_39,P62593,0.98674,NO,50,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-2.979,-3.95,0.971,,0.912,T,A,0.61,1.24,10.736,,77.62,HPP,-2.134,0.0495842,0.0047211,0.98674 beta-lactamase_625_G253D,beta-lactamase_625_253,TEM-1,beta-lactamase_625,P62593,0.98674,NO,253,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.213352,0.00786358,0.98674 beta-lactamase_39_G39P,beta-lactamase_39_39,TEM-1,beta-lactamase_39,P62593,0.986742,NO,39,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.864,-3.073,1.209,,0.701,T,L,0.29,0.47,1.454,,77.62,HOH,-1.53633,0.0495842,0.00487611,0.986742 beta-lactamase_156_S221N,beta-lactamase_156_221,TEM-1,beta-lactamase_156,P62593,0.986743,NO,221,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.754,-3.696,1.942,,0.624,H,A,0.27,-0.2,17.729,17.729,74.48,BPH,-1.59967,0.111618,0.0046094,0.986743 beta-lactamase_156_A77F,beta-lactamase_156_77,TEM-1,beta-lactamase_156,P62593,0.986749,NO,77,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.234,-4.125,2.891,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.111618,0.00282362,0.986749 beta-lactamase_39_G265N,beta-lactamase_39_265,TEM-1,beta-lactamase_39,P62593,0.986749,NO,265,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.0495842,0.00811926,0.986749 beta-lactamase_P60I,beta-lactamase_60,TEM-1,beta-lactamase,P62593,0.986749,NO,60,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-2.469,-3.895,1.426,5.51353,0.256,T,A,0.73,-0.56,3.653,,77.62,BOA,-1.97633,0.221079,0.00521318,0.986749 kka2_1:4_P12H,kka2_1:4_12,Kka2,kka2_1:4,P00552,0.986753,NO,12,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.853,-4.718,3.865,,,,B,0.52,1.25,0.843,,48.11,POH,-1.80767,0.168804,0.00500011,0.986753 gb1_A246G,gb1_246,gb1,gb1,P06654,0.986758,NO,246,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.175,-2.644,1.469,,,,,,,,,,AHH,-1.87033,0.177985,0.00190625,0.986758 beta-lactamase_156_T139I,beta-lactamase_156_139,TEM-1,beta-lactamase_156,P62593,0.986759,NO,139,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.901,-3.075,1.174,,0.216,H,A,0.22,0.39,16.34,16.34,77.62,PPH,-2.04667,0.111618,0.00441837,0.986759 beta-lactamase_156_K254A,beta-lactamase_156_254,TEM-1,beta-lactamase_156,P62593,0.986763,NO,254,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.111618,0.00369,0.986763 beta-lactamase_625_H151C,beta-lactamase_625_151,TEM-1,beta-lactamase_625,P62593,0.986767,NO,151,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-2.96,-5.124,2.164,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.213352,0.00216946,0.986767 PSD95pdz3_A343N,PSD95pdz3_343,PSD95pdz3,PSD95pdz3,P31016,0.986776,NO,343,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.307,-3.58,2.273,5.585,,,,,14.728,,,,HHO,-1.22067,0.0758425,0.000798084,0.986776 kka2_1:2_D159T,kka2_1:2_159,Kka2,kka2_1:2,P00552,0.986779,NO,159,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.82,-3.513,2.693,,0.28,.,B,0.75,1.25,0.899,,48.11,HAA,-1.48333,0.295029,0.0030485,0.986779 beta-lactamase_625_R63E,beta-lactamase_625_63,TEM-1,beta-lactamase_625,P62593,0.986781,NO,63,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-0.943,-3.298,2.355,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.213352,0.00126938,0.986781 beta-lactamase_156_H287K,beta-lactamase_156_287,TEM-1,beta-lactamase_156,P62593,0.986785,NO,287,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,,,,,,,,,,,,,BBH,-1.111,0.111618,,0.986785 Pab1_N187G,Pab1_187,Pab1,Pab1,P04147,0.986788,NO,187,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-1.224,-2.829,1.605,,0.456,S,b,,1.87,,,,HPO,-1.272,0.175299,0.00083165,0.986788 beta-lactamase_156_G90V,beta-lactamase_156_90,TEM-1,beta-lactamase_156,P62593,0.986789,NO,90,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-2.091,-3.033,0.942,,0.598,T,A,0.29,0.32,0.319,,77.62,HOB,-1.52633,0.111618,0.00490273,0.986789 beta-lactamase_156_A247C,beta-lactamase_156_247,TEM-1,beta-lactamase_156,P62593,0.986791,NO,247,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.111618,0.00611275,0.986791 beta-lactamase_156_S57Q,beta-lactamase_156_57,TEM-1,beta-lactamase_156,P62593,0.986799,NO,57,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.918,-3.995,2.077,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.111618,0.00492804,0.986799 beta-lactamase_625_Q203T,beta-lactamase_625_203,TEM-1,beta-lactamase_625,P62593,0.9868,NO,203,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.168,-2.523,0.355,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.213352,0.00631514,0.9868 beta-lactamase_A266Q,beta-lactamase_266,TEM-1,beta-lactamase,P62593,0.986801,NO,266,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.369,-3.043,1.674,5.02057,0.175,S,B,0.52,0.07,1.832,,64.34,PHP,-2.08567,0.221079,0.0140785,0.986801 beta-lactamase_625_S96H,beta-lactamase_625_96,TEM-1,beta-lactamase_625,P62593,0.986806,NO,96,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.27,-3.418,1.148,,0.368,,b,0.27,0.39,5.244,,73.78,HPP,-2.019,0.213352,0.00551835,0.986806 beta-lactamase_625_T139Y,beta-lactamase_625_139,TEM-1,beta-lactamase_625,P62593,0.986809,NO,139,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.901,-4.252,2.351,,0.216,H,A,0.22,0.39,2.256,,77.62,PPH,-2.04667,0.213352,0.00441837,0.986809 beta-lactamase_625_G236T,beta-lactamase_625_236,TEM-1,beta-lactamase_625,P62593,0.986811,NO,236,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.784,-3.55,2.766,,0.241,,b,0.29,-0.59,3.506,,64.69,HOO,-1.025,0.213352,0.00162372,0.986811 beta-lactamase_39_A185G,beta-lactamase_39_185,TEM-1,beta-lactamase_39,P62593,0.986817,NO,185,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.406,-3.37,1.964,,,H,A,0.46,-1.02,2.68,,65.03,HHP,-1.84033,0.0495842,0.00467449,0.986817 beta-lactamase_156_K286M,beta-lactamase_156_286,TEM-1,beta-lactamase_156,P62593,0.986824,NO,286,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.111618,,0.986824 beta-lactamase_156_L199E,beta-lactamase_156_199,TEM-1,beta-lactamase_156,P62593,0.986825,NO,199,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-2.942,-2.604,-0.338,,0.832,H,A,0.55,0.42,1.552,,77.62,PHH,-2.32933,0.111618,0.0048649,0.986825 beta-lactamase_39_A34T,beta-lactamase_39_34,TEM-1,beta-lactamase_39,P62593,0.986826,NO,34,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.059,-2.5,0.441,,,H,A,0.46,-0.54,13.292,13.292,73.78,AHA,-1.74967,0.0495842,0.00407913,0.986826 beta-lactamase_39_T187E,beta-lactamase_39_187,TEM-1,beta-lactamase_39,P62593,0.98683,NO,187,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.401,-3.52,2.119,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.0495842,0.00491782,0.98683 beta-lactamase_K190K,beta-lactamase_190,TEM-1,beta-lactamase,P62593,0.98683,NO,190,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.994,-1.994,,5.49163,0.371,H,A,1.82,0.16,29.753,29.753,77.62,BBH,-1.64167,0.221079,0.00574527,0.98683 beta-lactamase_39_S233Q,beta-lactamase_39_233,TEM-1,beta-lactamase_39,P62593,0.986831,NO,233,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.886,-3.939,2.053,,0.016,E,B,0.27,-1.01,5.361,,77.62,BPO,-1.17267,0.0495842,0.00311415,0.986831 kka2_1:4_P76C,kka2_1:4_76,Kka2,kka2_1:4,P00552,0.986831,NO,76,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.449,-5.046,3.597,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.168804,0.00625685,0.986831 beta-lactamase_D207L,beta-lactamase_207,TEM-1,beta-lactamase,P62593,0.986838,NO,207,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.064,-3.704,1.64,5.40404,0.409,H,A,0.23,0.12,1.975,,77.62,HAH,-1.77033,0.221079,0.00592942,0.986838 beta-lactamase_39_Y262V,beta-lactamase_39_262,TEM-1,beta-lactamase_39,P62593,0.986846,NO,262,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.0495842,0.00853516,0.986846 beta-lactamase_156_P250S,beta-lactamase_156_250,TEM-1,beta-lactamase_156,P62593,0.986851,NO,250,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.111618,0.00550899,0.986851 beta-lactamase_156_E169F,beta-lactamase_156_169,TEM-1,beta-lactamase_156,P62593,0.986856,NO,169,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.23,-4.322,3.092,,0.337,,A,1.04,1,3.516,,73.08,PAH,-1.16533,0.111618,0.00400994,0.986856 beta-lactamase_2500_D252W,beta-lactamase_2500_252,TEM-1,beta-lactamase_2500,P62593,0.986858,NO,252,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.94,,,,0.766,,B,1.59,1.16,,,67.83,OAO,-2.0965,0.361275,0.00575769,0.986858 beta-lactamase_625_P181C,beta-lactamase_625_181,TEM-1,beta-lactamase_625,P62593,0.986873,NO,181,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.813,-5.009,4.196,,,H,A,0.52,-1.14,1.797,,61.54,HOH,-1.795,0.213352,0.000703122,0.986873 beta-lactamase_625_R220K,beta-lactamase_625_220,TEM-1,beta-lactamase_625,P62593,0.986885,NO,220,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-0.942,-2.865,1.923,,0.295,I,A,1.2,-0.76,5.086,,74.48,HBP,-1.33633,0.213352,0.00232421,0.986885 Pab1_E195R,Pab1_195,Pab1,Pab1,P04147,0.986888,NO,195,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.2,-3.294,2.094,,,,,,,,,,PAH,-1.72467,0.175299,0.000620107,0.986888 beta-lactamase_39_N50E,beta-lactamase_39_50,TEM-1,beta-lactamase_39,P62593,0.986892,NO,50,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-2.979,-2.315,-0.664,,0.912,T,A,0.61,1.24,10.736,,77.62,HPP,-2.134,0.0495842,0.0047211,0.986892 beta-lactamase_156_S241M,beta-lactamase_156_241,TEM-1,beta-lactamase_156,P62593,0.986893,NO,241,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.111618,0.00452736,0.986893 beta-lactamase_625_S283V,beta-lactamase_625_283,TEM-1,beta-lactamase_625,P62593,0.986893,NO,283,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.213352,0.0429138,0.986893 beta-lactamase_Q88R,beta-lactamase_88,TEM-1,beta-lactamase,P62593,0.986893,NO,88,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.086,-2.458,0.372,5.8056,0.807,,B,0.12,2.03,1.84,,77.62,APH,-1.53433,0.221079,0.00504167,0.986893 beta-lactamase_2500_K286L,beta-lactamase_2500_286,TEM-1,beta-lactamase_2500,P62593,0.986901,NO,286,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.361275,,0.986901 beta-lactamase_39_N50R,beta-lactamase_39_50,TEM-1,beta-lactamase_39,P62593,0.986903,NO,50,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-2.979,-3.883,0.904,,0.912,T,A,0.61,1.24,10.736,,77.62,HPP,-2.134,0.0495842,0.0047211,0.986903 beta-lactamase_625_E175Q,beta-lactamase_625_175,TEM-1,beta-lactamase_625,P62593,0.986903,NO,175,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.336,-3.092,0.756,,0.551,,A,1.04,1.05,8.527,8.527,77.62,AAB,-1.31233,0.213352,0.00482205,0.986903 beta-lactamase_156_I45Q,beta-lactamase_156_45,TEM-1,beta-lactamase_156,P62593,0.986905,NO,45,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-2.421,-3.24,0.819,,,E,B,0.48,-0.3,2.256,,77.62,HHA,-2.30267,0.111618,0.00452842,0.986905 beta-lactamase_39_D99S,beta-lactamase_39_99,TEM-1,beta-lactamase_39,P62593,0.986907,NO,99,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.191,-3.286,2.095,,0.402,G,A,0.75,0.36,0.374,,64.69,PAH,-1.794,0.0495842,0.00305446,0.986907 beta-lactamase_156_D161I,beta-lactamase_156_161,TEM-1,beta-lactamase_156,P62593,0.986912,NO,161,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.891,-4.034,3.143,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.111618,0.000897697,0.986912 beta-lactamase_156_R202M,beta-lactamase_156_202,TEM-1,beta-lactamase_156,P62593,0.986918,NO,202,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.292,-4.499,3.207,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.111618,0.00321899,0.986918 beta-lactamase_156_P172R,beta-lactamase_156_172,TEM-1,beta-lactamase_156,P62593,0.986922,NO,172,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.998,-3.96,2.962,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.111618,0.00312594,0.986922 PSD95pdz3_N363T,PSD95pdz3_363,PSD95pdz3,PSD95pdz3,P31016,0.986922,NO,363,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-1.41,-2.878,1.468,5.23349,,,,,20.7037,,,,HPO,-1.29433,0.0758425,0.000524014,0.986922 beta-lactamase_156_R63S,beta-lactamase_156_63,TEM-1,beta-lactamase_156,P62593,0.986925,NO,63,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-0.943,-3.435,2.492,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.111618,0.00126938,0.986925 beta-lactamase_0_N152R,beta-lactamase_0_152,TEM-1,beta-lactamase_0,P62593,0.986926,NO,152,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-2.757,-2.835,0.078,,0.863,H,A,0.61,0.92,2.151,,77.62,BPH,-2.97,0.0500837,0.00471429,0.986926 beta-lactamase_156_H151S,beta-lactamase_156_151,TEM-1,beta-lactamase_156,P62593,0.986931,NO,151,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-2.96,-2.636,-0.324,,0.594,H,A,0.17,0.1,1.401,,77.62,HBP,-2.34767,0.111618,0.00216946,0.986931 beta-lactamase_156_L191H,beta-lactamase_156_191,TEM-1,beta-lactamase_156,P62593,0.986931,NO,191,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.087,-4.898,3.811,,,H,A,0.55,0.09,1.372,,63.29,BHH,-1.445,0.111618,0.00263549,0.986931 beta-lactamase_I11V,beta-lactamase_11,TEM-1,beta-lactamase,P62593,0.986932,NO,11,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.745,-1.933,0.188,,,,,,,3.135,,66.08,HHO,-1.79467,0.221079,0.00261325,0.986932 kka2_1:2_H139K,kka2_1:2_139,Kka2,kka2_1:2,P00552,0.986932,NO,139,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-2.809,-2.699,-0.11,,0.471,H,A,0.87,0.68,13.912,13.912,63.64,BBB,-2.22,0.295029,0.00734779,0.986932 beta-lactamase_39_R189N,beta-lactamase_39_189,TEM-1,beta-lactamase_39,P62593,0.986933,NO,189,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.844,-3.633,1.789,,0.278,H,A,1.2,1.01,12.11,12.11,72.73,HBB,-1.668,0.0495842,0.0050699,0.986933 beta-lactamase_2500_T138L,beta-lactamase_2500_138,TEM-1,beta-lactamase_2500,P62593,0.986937,NO,138,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.506,-3.638,1.132,,0.662,H,A,0.22,-0.03,30.445,30.445,73.78,HPP,-1.81233,0.361275,0.00487868,0.986937 beta-lactamase_156_A268D,beta-lactamase_156_268,TEM-1,beta-lactamase_156,P62593,0.986941,NO,268,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.111618,0.0102525,0.986941 beta-lactamase_2500_I277V,beta-lactamase_2500_277,TEM-1,beta-lactamase_2500,P62593,0.986941,NO,277,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.361275,0.0169305,0.986941 beta-lactamase_625_T198G,beta-lactamase_625_198,TEM-1,beta-lactamase_625,P62593,0.986941,NO,198,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.168,-3.295,1.127,,0.489,,B,0.22,-0.13,0.37,,73.78,HPH,-1.98767,0.213352,0.004311,0.986941 beta-lactamase_2500_H156S,beta-lactamase_2500_156,TEM-1,beta-lactamase_2500,P62593,0.986945,NO,156,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-3.156,-2.584,-0.572,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.361275,0.00468596,0.986945 beta-lactamase_156_L197D,beta-lactamase_156_197,TEM-1,beta-lactamase_156,P62593,0.986946,NO,197,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.853,-4.107,3.254,,0.007,S,B,0.55,0.33,1.58,,60.14,HHP,-1.833,0.111618,0.00144602,0.986946 beta-lactamase_156_V117F,beta-lactamase_156_117,TEM-1,beta-lactamase_156,P62593,0.98695,NO,117,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.53,-3.756,2.226,,,H,A,0.44,-0.34,1.182,,65.03,PHB,-1.741,0.111618,0.00467906,0.98695 PSD95pdz3_A390N,PSD95pdz3_390,PSD95pdz3,PSD95pdz3,P31016,0.986952,NO,390,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.307,-3.58,2.273,5.03823,,,,,12.46,,,,HHP,-1.54467,0.0758425,0.00104603,0.986952 beta-lactamase_625_S122K,beta-lactamase_625_122,TEM-1,beta-lactamase_625,P62593,0.986959,NO,122,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.406,-3.55,1.144,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.213352,0.00497825,0.986959 beta-lactamase_M127V,beta-lactamase_127,TEM-1,beta-lactamase,P62593,0.986959,NO,127,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-2.251,-2.333,0.082,5.40552,0.312,S,A,1.07,0.32,1.671,,72.73,PHP,-1.40433,0.221079,0.00437927,0.986959 beta-lactamase_2500_G90W,beta-lactamase_2500_90,TEM-1,beta-lactamase_2500,P62593,0.986961,NO,90,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-2.091,-5.515,3.424,,0.598,T,A,0.29,0.32,1.2,,77.62,HOB,-1.52633,0.361275,0.00490273,0.986961 beta-lactamase_0_R220L,beta-lactamase_0_220,TEM-1,beta-lactamase_0,P62593,0.986962,NO,220,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-0.942,-3.356,2.414,,0.295,I,A,1.2,-0.76,21.573,21.573,74.48,HBP,-1.33633,0.0500837,0.00232421,0.986962 beta-lactamase_156_A282H,beta-lactamase_156_282,TEM-1,beta-lactamase_156,P62593,0.98698,NO,282,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.111618,0.0449821,0.98698 beta-lactamase_156_L79I,beta-lactamase_156_79,TEM-1,beta-lactamase_156,P62593,0.986982,NO,79,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.842,-2.934,2.092,,0.007,H,A,0.55,-0.16,1.831,,50.35,HHP,-1.44333,0.111618,0.000947397,0.986982 beta-lactamase_625_G52H,beta-lactamase_625_52,TEM-1,beta-lactamase_625,P62593,0.986983,NO,52,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.149,-4.712,3.563,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.213352,0.00340138,0.986983 beta-lactamase_39_L196A,beta-lactamase_39_196,TEM-1,beta-lactamase_39,P62593,0.986987,NO,196,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-2.478,-1.974,-0.504,,0.518,S,A,0.55,1.35,12.152,12.152,77.62,AHH,-1.839,0.0495842,0.00512144,0.986987 beta-lactamase_2500_R239W,beta-lactamase_2500_239,TEM-1,beta-lactamase_2500,P62593,0.98699,NO,239,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.361275,0.00213852,0.98699 beta-lactamase_625_L111G,beta-lactamase_625_111,TEM-1,beta-lactamase_625,P62593,0.98699,NO,111,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.76,-3.666,1.906,,0.328,T,A,0.55,0.93,2.26,,64.34,BHP,-1.884,0.213352,0.00480671,0.98699 beta-lactamase_625_Q86K,beta-lactamase_625_86,TEM-1,beta-lactamase_625,P62593,0.986991,NO,86,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.4,-2.554,0.154,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.213352,0.00450027,0.986991 beta-lactamase_39_H156S,beta-lactamase_39_156,TEM-1,beta-lactamase_39,P62593,0.986992,NO,156,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-3.156,-2.584,-0.572,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.0495842,0.00468596,0.986992 beta-lactamase_39_N152R,beta-lactamase_39_152,TEM-1,beta-lactamase_39,P62593,0.986992,NO,152,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-2.757,-2.835,0.078,,0.863,H,A,0.61,0.92,4.038,,77.62,BPH,-2.97,0.0495842,0.00471429,0.986992 beta-lactamase_39_S96Q,beta-lactamase_39_96,TEM-1,beta-lactamase_39,P62593,0.986992,NO,96,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.27,-2.919,0.649,,0.368,,b,0.27,0.39,2.516,,73.78,HPP,-2.019,0.0495842,0.00551835,0.986992 beta-lactamase_2500_M180E,beta-lactamase_2500_180,TEM-1,beta-lactamase_2500,P62593,0.986993,NO,180,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-2.795,-3.532,0.737,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.361275,0.00552048,0.986993 beta-lactamase_156_P250C,beta-lactamase_156_250,TEM-1,beta-lactamase_156,P62593,0.986998,NO,250,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.111618,0.00550899,0.986998 beta-lactamase_39_T186W,beta-lactamase_39_186,TEM-1,beta-lactamase_39,P62593,0.986999,NO,186,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.522,-5.446,2.924,,0.396,H,A,0.22,-0.28,0.515,,77.62,HPP,-1.77633,0.0495842,0.00485034,0.986999 beta-lactamase_0_A200T,beta-lactamase_0_200,TEM-1,beta-lactamase_0,P62593,0.987,NO,200,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.878,-2.493,0.615,,0.757,H,A,0.46,-0.19,16.368,16.368,77.62,HHP,-2.001,0.0500837,0.0060056,0.987 beta-lactamase_156_A148Q,beta-lactamase_156_148,TEM-1,beta-lactamase_156,P62593,0.987,NO,148,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.757,-3.083,1.326,,0.379,H,A,0.46,-0.55,3.551,,72.73,PHH,-1.40167,0.111618,0.00547053,0.987 beta-lactamase_G76G,beta-lactamase_76,TEM-1,beta-lactamase,P62593,0.987,NO,76,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.189,-1.189,,4.73862,,H,A,2.05,-0.67,3.059,,67.83,OOH,-1.22267,0.221079,0.00476637,0.987 beta-lactamase_625_M180K,beta-lactamase_625_180,TEM-1,beta-lactamase_625,P62593,0.987001,NO,180,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-2.795,-3.525,0.73,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.213352,0.00552048,0.987001 beta-lactamase_2500_L49V,beta-lactamase_2500_49,TEM-1,beta-lactamase_2500,P62593,0.987002,NO,49,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.897,-2.549,0.652,,0.131,T,A,0.55,0.04,6.681,,64.69,AHP,-1.99233,0.361275,0.00401477,0.987002 beta-lactamase_2500_E61L,beta-lactamase_2500_61,TEM-1,beta-lactamase_2500,P62593,0.987003,NO,61,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.115,-3.769,1.654,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.361275,0.00440955,0.987003 beta-lactamase_39_G39M,beta-lactamase_39_39,TEM-1,beta-lactamase_39,P62593,0.987007,NO,39,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.864,-4.879,3.015,,0.701,T,L,0.29,0.47,1.454,,77.62,HOH,-1.53633,0.0495842,0.00487611,0.987007 beta-lactamase_39_G114T,beta-lactamase_39_114,TEM-1,beta-lactamase_39,P62593,0.987014,NO,114,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.094,-2.276,1.182,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.0495842,0.00224919,0.987014 beta-lactamase_156_L100K,beta-lactamase_156_100,TEM-1,beta-lactamase_156,P62593,0.987017,NO,100,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.218,-3.837,2.619,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.111618,0.00413885,0.987017 beta-lactamase_625_Q267S,beta-lactamase_625_267,TEM-1,beta-lactamase_625,P62593,0.987018,NO,267,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.213352,0.0102128,0.987018 beta-lactamase_0_A278C,beta-lactamase_0_278,TEM-1,beta-lactamase_0,P62593,0.987019,NO,278,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.348,,,,0.015,H,A,0.48,-0.85,4.624,,63.29,HHA,-1.41833,0.0500837,0.0310297,0.987019 beta-lactamase_0_I280N,beta-lactamase_0_280,TEM-1,beta-lactamase_0,P62593,0.987019,NO,280,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.0500837,0.0530888,0.987019 beta-lactamase_156_R81D,beta-lactamase_156_81,TEM-1,beta-lactamase_156,P62593,0.987024,NO,81,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.466,-3.611,2.145,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.111618,0.00499763,0.987024 beta-lactamase_39_N152T,beta-lactamase_39_152,TEM-1,beta-lactamase_39,P62593,0.987028,NO,152,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-2.757,-2.377,-0.38,,0.863,H,A,0.61,0.92,4.038,,77.62,BPH,-2.97,0.0495842,0.00471429,0.987028 beta-lactamase_156_I171M,beta-lactamase_156_171,TEM-1,beta-lactamase_156,P62593,0.987041,NO,171,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-2.431,-4.454,2.023,,0.361,,B,0.48,0.53,3.869,,77.62,HHO,-1.55533,0.111618,0.00623355,0.987041 beta-lactamase_39_K254N,beta-lactamase_39_254,TEM-1,beta-lactamase_39,P62593,0.987041,NO,254,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.0495842,0.00369,0.987041 beta-lactamase_156_G90N,beta-lactamase_156_90,TEM-1,beta-lactamase_156,P62593,0.987049,NO,90,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-2.091,-2.941,0.85,,0.598,T,A,0.29,0.32,0.319,,77.62,HOB,-1.52633,0.111618,0.00490273,0.987049 beta-lactamase_156_T126Q,beta-lactamase_156_126,TEM-1,beta-lactamase_156,P62593,0.987051,NO,126,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.122,-3.945,2.823,,0.05,H,A,0.22,-0.05,1.14,,44.41,HPH,-1.60467,0.111618,0.00244552,0.987051 beta-lactamase_39_P217H,beta-lactamase_39_217,TEM-1,beta-lactamase_39,P62593,0.987053,NO,217,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-2.062,-3.354,1.292,,0.496,I,A,0.52,-0.33,21.172,21.172,74.48,OOH,-1.64333,0.0495842,0.00463211,0.987053 beta-lactamase_0_V101I,beta-lactamase_0_101,TEM-1,beta-lactamase_0,P62593,0.987057,NO,101,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.295,-2.207,0.912,,0.342,,B,0.44,0,1.61,,73.08,HHA,-1.54367,0.0500837,0.00374492,0.987057 beta-lactamase_156_L111F,beta-lactamase_156_111,TEM-1,beta-lactamase_156,P62593,0.987063,NO,111,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.76,-2.976,1.216,,0.328,T,A,0.55,0.93,2.26,,64.34,BHP,-1.884,0.111618,0.00480671,0.987063 beta-lactamase_39_E272A,beta-lactamase_39_272,TEM-1,beta-lactamase_39,P62593,0.987064,NO,272,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.127,,,,0.081,H,A,0.43,-0.97,12.983,12.983,63.64,AAB,-1.56333,0.0495842,0.00545371,0.987064 beta-lactamase_L10M,beta-lactamase_10,TEM-1,beta-lactamase,P62593,0.987066,NO,10,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.623,-4.09,2.467,,,,,,,2.467,,65.38,HHH,-1.83833,0.221079,0.00296968,0.987066 beta-lactamase_2500_I206Q,beta-lactamase_2500_206,TEM-1,beta-lactamase_2500,P62593,0.987071,NO,206,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-2.429,-2.554,0.125,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.361275,0.00528934,0.987071 beta-lactamase_0_G265H,beta-lactamase_0_265,TEM-1,beta-lactamase_0,P62593,0.987072,NO,265,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.0500837,0.00811926,0.987072 beta-lactamase_156_R59C,beta-lactamase_156_59,TEM-1,beta-lactamase_156,P62593,0.987073,NO,59,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.345,-2.854,1.509,,0.329,S,L,1.2,-0.09,2.995,,73.08,HBO,-2.24267,0.111618,0.00318082,0.987073 beta-lactamase_625_N98S,beta-lactamase_625_98,TEM-1,beta-lactamase_625,P62593,0.987074,NO,98,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-2.973,-2.34,-0.633,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.213352,0.00505389,0.987074 beta-lactamase_156_G85S,beta-lactamase_156_85,TEM-1,beta-lactamase_156,P62593,0.987079,NO,85,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.011,-3.264,2.253,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.111618,0.00252173,0.987079 beta-lactamase_156_V157N,beta-lactamase_156_157,TEM-1,beta-lactamase_156,P62593,0.98708,NO,157,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.751,-3.925,2.174,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.111618,0.00506849,0.98708 beta-lactamase_156_T116S,beta-lactamase_156_116,TEM-1,beta-lactamase_156,P62593,0.987082,NO,116,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.28,-1.932,0.652,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.111618,0.00336175,0.987082 beta-lactamase_156_Y103L,beta-lactamase_156_103,TEM-1,beta-lactamase_156,P62593,0.987083,NO,103,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-1.33,-3.402,2.072,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.111618,0.00443048,0.987083 kka2_1:2_G95N,kka2_1:2_95,Kka2,kka2_1:2,P00552,0.987087,NO,95,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-2.403,-2.561,0.158,,0.126,E,B,0.29,-0.74,0.359,,71.59,HOA,-2.198,0.295029,0.00743616,0.987087 beta-lactamase_39_N152L,beta-lactamase_39_152,TEM-1,beta-lactamase_39,P62593,0.987088,NO,152,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-2.757,-3.55,0.793,,0.863,H,A,0.61,0.92,4.038,,77.62,BPH,-2.97,0.0495842,0.00471429,0.987088 beta-lactamase_156_R257A,beta-lactamase_156_257,TEM-1,beta-lactamase_156,P62593,0.987089,NO,257,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.111618,0.00756629,0.987089 beta-lactamase_2500_N98R,beta-lactamase_2500_98,TEM-1,beta-lactamase_2500,P62593,0.98709,NO,98,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-2.973,-2.618,-0.355,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.361275,0.00505389,0.98709 beta-lactamase_156_G216D,beta-lactamase_156_216,TEM-1,beta-lactamase_156,P62593,0.987091,NO,216,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.477,-1.722,0.245,,0.437,I,A,0.29,-0.58,12.464,12.464,74.48,HOO,-1.68067,0.111618,0.00639568,0.987091 beta-lactamase_39_E175P,beta-lactamase_39_175,TEM-1,beta-lactamase_39,P62593,0.987093,NO,175,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.336,-1.972,-0.364,,0.551,,A,1.04,1.05,3.676,,77.62,AAB,-1.31233,0.0495842,0.00482205,0.987093 beta-lactamase_156_G226M,beta-lactamase_156_226,TEM-1,beta-lactamase_156,P62593,0.987096,NO,226,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.461,-4.924,3.463,,0.701,T,l,0.29,-0.25,3.199,,74.48,HOH,-1.42933,0.111618,0.00665294,0.987096 beta-lactamase_39_L199S,beta-lactamase_39_199,TEM-1,beta-lactamase_39,P62593,0.987099,NO,199,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-2.942,-2.568,-0.374,,0.832,H,A,0.55,0.42,15.504,15.504,77.62,PHH,-2.32933,0.0495842,0.0048649,0.987099 kka2_1:8_E169M,kka2_1:8_169,Kka2,kka2_1:8,P00552,0.9871,NO,169,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.996,-3.601,1.605,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.100394,0.00730086,0.9871 kka2_1:8_E169M,kka2_1:8_169,Kka2,kka2_1:8,P00552,0.9871,NO,169,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.996,-3.601,1.605,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.100394,0.00730086,0.9871 gb1_T279C,gb1_279,gb1,gb1,P06654,0.987107,NO,279,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.32,-4.477,3.157,,,,,,,0.529,,35.71,HPH,-1.50067,0.177985,0.00421454,0.987107 beta-lactamase_0_E175R,beta-lactamase_0_175,TEM-1,beta-lactamase_0,P62593,0.987111,NO,175,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.336,-3.064,0.728,,0.551,,A,1.04,1.05,2.334,,77.62,AAB,-1.31233,0.0500837,0.00482205,0.987111 beta-lactamase_625_P165Q,beta-lactamase_625_165,TEM-1,beta-lactamase_625,P62593,0.987113,NO,165,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.373,-3.97,2.597,,0.203,T,A,0.52,-0.31,0.414,,73.78,AOA,-1.359,0.213352,0.00549538,0.987113 beta-lactamase_625_I261C,beta-lactamase_625_261,TEM-1,beta-lactamase_625,P62593,0.987121,NO,261,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.213352,0.0123091,0.987121 Pab1_A185V,Pab1_185,Pab1,Pab1,P04147,0.987122,NO,185,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.702,-3.389,1.687,,,,,,,1.756,,63.26,AHH,-1.66167,0.175299,0.00144499,0.987122 beta-lactamase_156_R63H,beta-lactamase_156_63,TEM-1,beta-lactamase_156,P62593,0.987123,NO,63,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-0.943,-4.313,3.37,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.111618,0.00126938,0.987123 beta-lactamase_39_D83N,beta-lactamase_39_83,TEM-1,beta-lactamase_39,P62593,0.987124,NO,83,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.066,-3.355,2.289,,0.354,H,A,0.75,0.22,0.752,,48.95,HAH,-1.34733,0.0495842,0.00205968,0.987124 beta-lactamase_625_T198Q,beta-lactamase_625_198,TEM-1,beta-lactamase_625,P62593,0.987126,NO,198,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.168,-2.734,0.566,,0.489,,B,0.22,-0.13,0.37,,73.78,HPH,-1.98767,0.213352,0.004311,0.987126 beta-lactamase_156_D113K,beta-lactamase_156_113,TEM-1,beta-lactamase_156,P62593,0.98713,NO,113,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.829,-2.696,0.867,,0.665,T,A,0.75,0.91,2.973,,73.08,PAO,-1.703,0.111618,0.00474112,0.98713 beta-lactamase_625_K144R,beta-lactamase_625_144,TEM-1,beta-lactamase_625,P62593,0.987132,NO,144,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-2.388,-3.055,0.667,,0.863,H,A,2.34,1.27,2.313,,77.62,OBA,-1.904,0.213352,0.00481141,0.987132 beta-lactamase_39_I229L,beta-lactamase_39_229,TEM-1,beta-lactamase_39,P62593,0.987135,NO,229,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.267,-2.225,0.958,,0.083,E,B,0.48,-0.76,1.114,,50,HHH,-1.58767,0.0495842,0.00477249,0.987135 beta-lactamase_2500_E102Y,beta-lactamase_2500_102,TEM-1,beta-lactamase_2500,P62593,0.987139,NO,102,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.118,-4.321,2.203,,0.722,S,B,1.04,1.82,1.336,,73.08,HAH,-1.581,0.361275,0.00486633,0.987139 beta-lactamase_156_D207V,beta-lactamase_156_207,TEM-1,beta-lactamase_156,P62593,0.98714,NO,207,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.064,-3.771,1.707,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.111618,0.00592942,0.98714 beta-lactamase_2500_E108R,beta-lactamase_2500_108,TEM-1,beta-lactamase_2500,P62593,0.987142,NO,108,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.46,-2.885,1.425,,0.572,G,A,1.04,1.87,1.147,,72.73,PAB,-1.437,0.361275,0.00413372,0.987142 beta-lactamase_156_Y262L,beta-lactamase_156_262,TEM-1,beta-lactamase_156,P62593,0.987143,NO,262,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.111618,0.00853516,0.987143 kka2_1:1_A247C,kka2_1:1_247,Kka2,kka2_1:1,P00552,0.987145,NO,247,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.459,-5.101,2.642,,1.01,S,A,0.46,0.65,7.731,7.731,92.05,HHH,-2.197,0.520039,0.0102428,0.987145 beta-lactamase_156_L248W,beta-lactamase_156_248,TEM-1,beta-lactamase_156,P62593,0.987149,NO,248,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.111618,0.00428493,0.987149 beta-lactamase_39_W288G,beta-lactamase_39_288,TEM-1,beta-lactamase_39,P62593,0.987151,NO,288,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,,,,,,,,,,,,,BHO,,0.0495842,,0.987151 beta-lactamase_2500_A282T,beta-lactamase_2500_282,TEM-1,beta-lactamase_2500,P62593,0.987155,NO,282,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.361275,0.0449821,0.987155 beta-lactamase_625_N98Y,beta-lactamase_625_98,TEM-1,beta-lactamase_625,P62593,0.987159,NO,98,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-2.973,-4.22,1.247,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.213352,0.00505389,0.987159 beta-lactamase_39_Q88M,beta-lactamase_39_88,TEM-1,beta-lactamase_39,P62593,0.98716,NO,88,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.086,-3.418,1.332,,0.807,,B,0.64,2.03,11.108,11.108,77.62,APH,-1.53433,0.0495842,0.00504167,0.98716 beta-lactamase_156_A268T,beta-lactamase_156_268,TEM-1,beta-lactamase_156,P62593,0.987162,NO,268,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.111618,0.0102525,0.987162 beta-lactamase_2500_D33H,beta-lactamase_2500_33,TEM-1,beta-lactamase_2500,P62593,0.987165,NO,33,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.321,-4.654,2.333,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.361275,0.00435556,0.987165 PSD95pdz3_K393W,PSD95pdz3_393,PSD95pdz3,PSD95pdz3,P31016,0.987165,NO,393,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.416,-5.004,3.588,5.42682,,,,,22.0122,,,,HBO,-1.4265,0.0758425,0.000879298,0.987165 beta-lactamase_625_C121A,beta-lactamase_625_121,TEM-1,beta-lactamase_625,P62593,0.987173,NO,121,C,A,CA,Special,Hydrophobic,5.07,6,0.93,195,121,89,-32,108.5,88.6,-19.9,-0.953,-2.902,1.949,,,H,A,0.46,-0.81,1.143,,63.29,HOP,-1.46767,0.213352,0.000744322,0.987173 beta-lactamase_39_Y103M,beta-lactamase_39_103,TEM-1,beta-lactamase_39,P62593,0.987175,NO,103,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-1.33,-4.627,3.297,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.0495842,0.00443048,0.987175 beta-lactamase_2500_A247Y,beta-lactamase_2500_247,TEM-1,beta-lactamase_2500,P62593,0.987178,NO,247,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.361275,0.00611275,0.987178 PSD95pdz3_S361M,PSD95pdz3_361,PSD95pdz3,PSD95pdz3,P31016,0.987178,NO,361,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.519,-4.162,2.643,4.8722,,,,,16.4533,,,,HPH,-1.47167,0.0758425,0.00055296,0.987178 beta-lactamase_156_G265L,beta-lactamase_156_265,TEM-1,beta-lactamase_156,P62593,0.987183,NO,265,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.111618,0.00811926,0.987183 beta-lactamase_39_H94D,beta-lactamase_39_94,TEM-1,beta-lactamase_39,P62593,0.987189,NO,94,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-2.5,-3,0.5,,0.776,,B,0.17,1.24,11.583,11.583,77.62,HBH,-1.872,0.0495842,0.00389226,0.987189 beta-lactamase_R189C,beta-lactamase_189,TEM-1,beta-lactamase,P62593,0.987191,NO,189,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.844,-5.229,3.385,5.74877,0.278,H,A,0.68,1.01,1.512,,72.73,HBB,-1.668,0.221079,0.0050699,0.987191 Pab1_G177R,Pab1_177,Pab1,Pab1,P04147,0.987192,NO,177,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-2.24,-3.632,1.392,,,,,,,,,,AOH,-1.94067,0.175299,0.00170727,0.987192 PSD95pdz3_L349R,PSD95pdz3_349,PSD95pdz3,PSD95pdz3,P31016,0.987192,NO,349,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.347,-3.615,2.268,5.14696,,,,,24.6438,,,,AHP,-1.37667,0.0758425,0.00071841,0.987192 beta-lactamase_2500_R273M,beta-lactamase_2500_273,TEM-1,beta-lactamase_2500,P62593,0.987193,NO,273,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.314,-4.698,2.384,,0.564,H,A,1.2,1.57,19.943,19.943,73.78,ABP,-1.841,0.361275,0.0077952,0.987193 beta-lactamase_625_H94A,beta-lactamase_625_94,TEM-1,beta-lactamase_625,P62593,0.987197,NO,94,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-2.5,-2.468,-0.032,,0.776,,B,0.17,1.24,19.42,19.42,77.62,HBH,-1.872,0.213352,0.00389226,0.987197 beta-lactamase_Q88K,beta-lactamase_88,TEM-1,beta-lactamase,P62593,0.987198,NO,88,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.086,-2.839,0.753,5.8056,0.807,,B,0.12,2.03,1.84,,77.62,APH,-1.53433,0.221079,0.00504167,0.987198 beta-lactamase_39_V31W,beta-lactamase_39_31,TEM-1,beta-lactamase_39,P62593,0.987204,NO,31,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.822,-5.287,3.465,,,H,A,0.44,-0.46,2.885,,73.78,BHB,-2.03767,0.0495842,0.00478065,0.987204 beta-lactamase_156_P172S,beta-lactamase_156_172,TEM-1,beta-lactamase_156,P62593,0.987205,NO,172,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.998,-2.394,1.396,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.111618,0.00312594,0.987205 beta-lactamase_625_W288F,beta-lactamase_625_288,TEM-1,beta-lactamase_625,P62593,0.987207,NO,288,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,,,,,,,,,,,,,BHO,,0.213352,,0.987207 beta-lactamase_E61V,beta-lactamase_61,TEM-1,beta-lactamase,P62593,0.98721,NO,61,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.115,-3.784,1.669,6.29701,0.775,T,a,0.52,1.29,1.975,,77.62,OAA,-1.92567,0.221079,0.00440955,0.98721 beta-lactamase_0_M153T,beta-lactamase_0_153,TEM-1,beta-lactamase_0,P62593,0.987215,NO,153,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-3.193,-2.237,-0.956,,0.14,T,A,0.55,-0.11,3.826,,77.62,PHO,-2.25767,0.0500837,0.00509109,0.987215 beta-lactamase_39_R59D,beta-lactamase_39_59,TEM-1,beta-lactamase_39,P62593,0.98722,NO,59,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.345,-3.634,2.289,,0.329,S,L,1.2,-0.09,1.806,,73.08,HBO,-2.24267,0.0495842,0.00318082,0.98722 beta-lactamase_156_L188T,beta-lactamase_156_188,TEM-1,beta-lactamase_156,P62593,0.987223,NO,188,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.166,-3.522,2.356,,,H,A,0.55,-0.3,1.574,,60.14,PHB,-1.47033,0.111618,0.00295687,0.987223 beta-lactamase_2500_E166T,beta-lactamase_2500_166,TEM-1,beta-lactamase_2500,P62593,0.987225,NO,166,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.756,-2.857,1.101,,0.508,G,A,1.04,1.05,2.124,,73.08,OAH,-1.42233,0.361275,0.00512989,0.987225 beta-lactamase_A230G,beta-lactamase_230,TEM-1,beta-lactamase,P62593,0.987229,NO,230,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.154,-1.479,0.325,4.54336,0.01,E,B,0.75,-1.17,1.97,,50,HHA,-1.079,0.221079,0.00516841,0.987229 beta-lactamase_156_Q86G,beta-lactamase_156_86,TEM-1,beta-lactamase_156,P62593,0.98723,NO,86,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.4,-2.887,0.487,,0.696,S,A,0.64,2.38,27.704,27.704,77.62,OPA,-1.61067,0.111618,0.00450027,0.98723 beta-lactamase_39_P65F,beta-lactamase_39_65,TEM-1,beta-lactamase_39,P62593,0.987231,NO,65,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.894,-4.306,3.412,,0.098,E,B,0.52,-0.62,0.623,,40.56,HOH,-1.03233,0.0495842,0.00152776,0.987231 beta-lactamase_625_P172C,beta-lactamase_625_172,TEM-1,beta-lactamase_625,P62593,0.987235,NO,172,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.998,-4.977,3.979,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.213352,0.00312594,0.987235 beta-lactamase_0_G243R,beta-lactamase_0_243,TEM-1,beta-lactamase_0,P62593,0.987243,NO,243,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.0500837,0.00464034,0.987243 beta-lactamase_156_R81C,beta-lactamase_156_81,TEM-1,beta-lactamase_156,P62593,0.987243,NO,81,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.466,-5.147,3.681,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.111618,0.00499763,0.987243 beta-lactamase_156_I54C,beta-lactamase_156_54,TEM-1,beta-lactamase_156,P62593,0.987245,NO,54,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-2.838,-5.056,2.218,,0.669,E,B,0.48,-0.14,0.541,,73.78,BHH,-2.337,0.111618,0.00403589,0.987245 beta-lactamase_2500_H24N,beta-lactamase_2500_24,TEM-1,beta-lactamase_2500,P62593,0.987246,NO,24,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-2.481,-3.496,1.015,,,,,,,0.467,,93.01,OBO,-2.0035,0.361275,0.00238894,0.987246 beta-lactamase_39_G85Y,beta-lactamase_39_85,TEM-1,beta-lactamase_39,P62593,0.987246,NO,85,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.011,-4.409,3.398,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.0495842,0.00252173,0.987246 beta-lactamase_156_Q276E,beta-lactamase_156_276,TEM-1,beta-lactamase_156,P62593,0.987247,NO,276,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.111618,0.0191712,0.987247 beta-lactamase_A170Y,beta-lactamase_170,TEM-1,beta-lactamase,P62593,0.987247,NO,170,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.237,-4.057,2.82,5.19261,0.126,,L,2.34,-0.35,2.427,,64.69,AHH,-1.63267,0.221079,0.00431903,0.987247 beta-lactamase_A280G,beta-lactamase_280,TEM-1,beta-lactamase,P62593,0.987247,NO,280,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.708,-2.604,0.896,4.74932,0.379,H,A,0.52,-0.72,1.785,,68.18,OHP,-1.66433,0.221079,0.0530888,0.987247 beta-lactamase_39_I229Y,beta-lactamase_39_229,TEM-1,beta-lactamase_39,P62593,0.987248,NO,229,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.267,-4.04,2.773,,0.083,E,B,0.48,-0.76,1.114,,50,HHH,-1.58767,0.0495842,0.00477249,0.987248 beta-lactamase_625_P143G,beta-lactamase_625_143,TEM-1,beta-lactamase_625,P62593,0.987248,NO,143,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.967,-3.499,2.532,,0.075,H,A,0.52,-0.37,1.445,,66.78,OOB,-1.354,0.213352,0.00114551,0.987248 beta-lactamase_0_A235R,beta-lactamase_0_235,TEM-1,beta-lactamase_0,P62593,0.98725,NO,235,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.266,-3.887,2.621,,0.32,E,B,0.46,-0.86,2.261,,50,OHO,-0.89,0.0500837,0.00493474,0.98725 beta-lactamase_625_M153Y,beta-lactamase_625_153,TEM-1,beta-lactamase_625,P62593,0.987252,NO,153,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-3.193,-4.187,0.994,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.213352,0.00509109,0.987252 beta-lactamase_2500_Q204C,beta-lactamase_2500_204,TEM-1,beta-lactamase_2500,P62593,0.987259,NO,204,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-1.382,-5.114,3.732,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.361275,0.00364106,0.987259 beta-lactamase_156_P165R,beta-lactamase_156_165,TEM-1,beta-lactamase_156,P62593,0.987263,NO,165,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.373,-3.877,2.504,,0.203,T,A,0.52,-0.31,3.907,,73.78,AOA,-1.359,0.111618,0.00549538,0.987263 beta-lactamase_156_Y262V,beta-lactamase_156_262,TEM-1,beta-lactamase_156,P62593,0.987264,NO,262,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.111618,0.00853516,0.987264 beta-lactamase_156_V82G,beta-lactamase_156_82,TEM-1,beta-lactamase_156,P62593,0.987268,NO,82,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.325,-2.644,1.319,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.111618,0.00397046,0.987268 beta-lactamase_0_D33I,beta-lactamase_0_33,TEM-1,beta-lactamase_0,P62593,0.987276,NO,33,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.321,-3.065,0.744,,0.366,H,A,0.75,0.33,12.514,12.514,77.62,BAH,-2.12133,0.0500837,0.00435556,0.987276 beta-lactamase_39_M184T,beta-lactamase_39_184,TEM-1,beta-lactamase_39,P62593,0.987285,NO,184,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.593,-2.764,1.171,,,H,A,0.55,-0.87,2.893,,62.94,HHH,-1.41,0.0495842,0.00356019,0.987285 beta-lactamase_39_V78F,beta-lactamase_39_78,TEM-1,beta-lactamase_39,P62593,0.987285,NO,78,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.459,-3.883,2.424,,,H,A,0.44,-0.47,1.132,,63.64,HHH,-1.17833,0.0495842,0.00492501,0.987285 beta-lactamase_2500_K109D,beta-lactamase_2500_109,TEM-1,beta-lactamase_2500,P62593,0.987286,NO,109,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.734,-2.919,1.185,,0.787,G,A,2.34,2.21,0.998,,72.73,ABB,-1.63333,0.361275,0.00462493,0.987286 PSD95pdz3_S361C,PSD95pdz3_361,PSD95pdz3,PSD95pdz3,P31016,0.98729,NO,361,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.519,-4.319,2.8,4.8722,,,,,16.4533,,,,HPH,-1.47167,0.0758425,0.00055296,0.98729 beta-lactamase_156_A185I,beta-lactamase_156_185,TEM-1,beta-lactamase_156,P62593,0.987292,NO,185,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.406,-3.361,1.955,,,H,A,0.46,-1.02,0.365,,65.03,HHP,-1.84033,0.111618,0.00467449,0.987292 beta-lactamase_2500_R275Y,beta-lactamase_2500_275,TEM-1,beta-lactamase_2500,P62593,0.987294,NO,275,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.361275,0.0141984,0.987294 beta-lactamase_156_S256W,beta-lactamase_156_256,TEM-1,beta-lactamase_156,P62593,0.987296,NO,256,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.111618,0.00710634,0.987296 beta-lactamase_L28M,beta-lactamase_28,TEM-1,beta-lactamase,P62593,0.9873,NO,28,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.579,-4.156,2.577,5.42969,0.277,H,A,0.07,-0.16,19.748,19.748,93.01,PHH,-2.11333,0.221079,0.00359321,0.9873 beta-lactamase_156_I229L,beta-lactamase_156_229,TEM-1,beta-lactamase_156,P62593,0.987302,NO,229,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.267,-2.225,0.958,,0.083,E,B,0.48,-0.76,1.114,,50,HHH,-1.58767,0.111618,0.00477249,0.987302 beta-lactamase_156_N98G,beta-lactamase_156_98,TEM-1,beta-lactamase_156,P62593,0.987303,NO,98,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-2.973,-3.401,0.428,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.111618,0.00505389,0.987303 PSD95pdz3_K393H,PSD95pdz3_393,PSD95pdz3,PSD95pdz3,P31016,0.987306,NO,393,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.416,-4.137,2.721,5.42682,,,,,22.0122,,,,HBO,-1.4265,0.0758425,0.000879298,0.987306 beta-lactamase_39_I206T,beta-lactamase_39_206,TEM-1,beta-lactamase_39,P62593,0.987312,NO,206,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-2.429,-2.077,-0.352,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.0495842,0.00528934,0.987312 beta-lactamase_2500_H156W,beta-lactamase_2500_156,TEM-1,beta-lactamase_2500,P62593,0.987314,NO,156,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-3.156,-5.55,2.394,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.361275,0.00468596,0.987314 beta-lactamase_625_S221K,beta-lactamase_625_221,TEM-1,beta-lactamase_625,P62593,0.987318,NO,221,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.754,-2.447,0.693,,0.624,H,A,0.27,-0.2,1.495,,74.48,BPH,-1.59967,0.213352,0.0046094,0.987318 beta-lactamase_2500_L192F,beta-lactamase_2500_192,TEM-1,beta-lactamase_2500,P62593,0.98732,NO,192,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.254,-2.572,1.318,,0.095,H,A,0.55,0.35,1.902,,60.14,HHP,-1.41833,0.361275,0.00558728,0.98732 beta-lactamase_625_T187V,beta-lactamase_625_187,TEM-1,beta-lactamase_625,P62593,0.987327,NO,187,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.401,-3.287,1.886,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.213352,0.00491782,0.987327 beta-lactamase_39_I93G,beta-lactamase_39_93,TEM-1,beta-lactamase_39,P62593,0.987328,NO,93,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.401,-3.805,2.404,,0.128,E,B,0.48,0.44,1.757,,67.83,BHB,-1.873,0.0495842,0.00527066,0.987328 beta-lactamase_156_R273W,beta-lactamase_156_273,TEM-1,beta-lactamase_156,P62593,0.987329,NO,273,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.314,-5.456,3.142,,0.564,H,A,1.2,1.57,20.248,20.248,73.78,ABP,-1.841,0.111618,0.0077952,0.987329 beta-lactamase_D250L,beta-lactamase_250,TEM-1,beta-lactamase,P62593,0.987333,NO,250,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.335,-3.633,1.298,5.72026,0.89,T,L,0.23,1.53,24.737,24.737,66.08,OAO,-1.85133,0.221079,0.00550899,0.987333 beta-lactamase_39_Q37D,beta-lactamase_39_37,TEM-1,beta-lactamase_39,P62593,0.987335,NO,37,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.134,-2.904,0.77,,0.613,H,A,0.64,1.98,22.282,22.282,73.08,APH,-2.06967,0.0495842,0.00425833,0.987335 WW_domain_K181H,WW_domain_181,Yap65,WW_domain,P46937,0.987347,NO,181,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.35,-4.295,2.945,5.0864,,,,,,0.176,,15.87,HBP,-1.247,0.153962,0.0033022,0.987347 beta-lactamase_625_N98F,beta-lactamase_625_98,TEM-1,beta-lactamase_625,P62593,0.987356,NO,98,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-2.973,-3.271,0.298,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.213352,0.00505389,0.987356 kka2_1:4_I246R,kka2_1:4_246,Kka2,kka2_1:4,P00552,0.987359,NO,246,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-2.008,-3.32,1.312,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.168804,0.0139479,0.987359 WW_domain_Q186H,WW_domain_186,Yap65,WW_domain,P46937,0.987364,NO,186,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-1.358,-4.007,2.649,4.88854,,,,,,,,,OPB,-1.207,0.153962,0.00161546,0.987364 beta-lactamase_156_L100V,beta-lactamase_156_100,TEM-1,beta-lactamase_156,P62593,0.987365,NO,100,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.218,-2.049,0.831,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.111618,0.00413885,0.987365 beta-lactamase_39_D271E,beta-lactamase_39_271,TEM-1,beta-lactamase_39,P62593,0.987366,NO,271,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.0495842,0.00752082,0.987366 beta-lactamase_P60R,beta-lactamase_60,TEM-1,beta-lactamase,P62593,0.987374,NO,60,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-2.469,-3.014,0.545,5.51353,0.256,T,A,0.73,-0.56,3.653,,77.62,BOA,-1.97633,0.221079,0.00521318,0.987374 beta-lactamase_625_L38H,beta-lactamase_625_38,TEM-1,beta-lactamase_625,P62593,0.987375,NO,38,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.343,-3.182,1.839,,0.088,H,A,0.55,0.2,1.986,,64.34,PHO,-1.78033,0.213352,0.00373244,0.987375 beta-lactamase_156_P250D,beta-lactamase_156_250,TEM-1,beta-lactamase_156,P62593,0.987377,NO,250,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-2.335,-1.83,-0.505,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.111618,0.00550899,0.987377 beta-lactamase_2500_D113K,beta-lactamase_2500_113,TEM-1,beta-lactamase_2500,P62593,0.987379,NO,113,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.829,-2.696,0.867,,0.665,T,A,0.75,0.91,21.104,21.104,73.08,PAO,-1.703,0.361275,0.00474112,0.987379 beta-lactamase_39_L28I,beta-lactamase_39_28,TEM-1,beta-lactamase_39,P62593,0.987379,NO,28,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.579,-2.204,0.625,,0.277,H,A,0.55,-0.16,3.262,,93.01,PHH,-2.11333,0.0495842,0.00359321,0.987379 beta-lactamase_N50N,beta-lactamase_50,TEM-1,beta-lactamase,P62593,0.987395,NO,50,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-2.979,-2.979,,5.51261,0.912,T,A,1.07,1.24,1.581,,77.62,HPP,-2.134,0.221079,0.0047211,0.987395 beta-lactamase_Q4K,beta-lactamase_4,TEM-1,beta-lactamase,P62593,0.987395,NO,4,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,,-2.085,-0.479,,,,,,,,,,HPB,,0.221079,0.00316562,0.987395 beta-lactamase_39_S104I,beta-lactamase_39_104,TEM-1,beta-lactamase_39,P62593,0.987399,NO,104,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.015,-3.786,2.771,,0.04,,b,0.27,0.57,4.02,,63.29,HPO,-1.05267,0.0495842,0.00218083,0.987399 beta-lactamase_156_L38I,beta-lactamase_156_38,TEM-1,beta-lactamase_156,P62593,0.987402,NO,38,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.343,-2.44,1.097,,0.088,H,A,0.55,0.2,13.556,13.556,64.34,PHO,-1.78033,0.111618,0.00373244,0.987402 beta-lactamase_39_L218E,beta-lactamase_39_218,TEM-1,beta-lactamase_39,P62593,0.987405,NO,218,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.391,-3.611,2.22,,,I,b,0.55,-0.53,2.038,,74.48,OHH,-1.58867,0.0495842,0.00618274,0.987405 kka2_1:4_E161R,kka2_1:4_161,Kka2,kka2_1:4,P00552,0.987408,NO,161,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.581,-3.888,2.307,,0.829,G,A,1.52,2.24,1.612,,92.05,AAB,-1.861,0.168804,0.00760103,0.987408 beta-lactamase_156_N168E,beta-lactamase_156_168,TEM-1,beta-lactamase_156,P62593,0.987414,NO,168,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-1.029,-3.29,2.261,,0.113,G,A,0.61,-0.4,1.014,,44.41,HPA,-1.13233,0.111618,0.00288667,0.987414 beta-lactamase_625_Q276W,beta-lactamase_625_276,TEM-1,beta-lactamase_625,P62593,0.987421,NO,276,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.213352,0.0191712,0.987421 beta-lactamase_625_A34C,beta-lactamase_625_34,TEM-1,beta-lactamase_625,P62593,0.987426,NO,34,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.059,-4.764,2.705,,,H,A,0.46,-0.54,3.614,,73.78,AHA,-1.74967,0.213352,0.00407913,0.987426 beta-lactamase_156_I245C,beta-lactamase_156_245,TEM-1,beta-lactamase_156,P62593,0.987431,NO,245,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.111618,0.00391032,0.987431 beta-lactamase_156_G265R,beta-lactamase_156_265,TEM-1,beta-lactamase_156,P62593,0.987432,NO,265,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.111618,0.00811926,0.987432 beta-lactamase_625_Q276R,beta-lactamase_625_276,TEM-1,beta-lactamase_625,P62593,0.987433,NO,276,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.213352,0.0191712,0.987433 Pab1_D144C,Pab1_144,Pab1,Pab1,P04147,0.987434,NO,144,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.189,-5.048,3.859,,0.616,H,A,,0.6,,,,HAP,-1.40567,0.175299,0.00121131,0.987434 beta-lactamase_39_G52M,beta-lactamase_39_52,TEM-1,beta-lactamase_39,P62593,0.987436,NO,52,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.149,-4.888,3.739,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.0495842,0.00340138,0.987436 beta-lactamase_625_G194C,beta-lactamase_625_194,TEM-1,beta-lactamase_625,P62593,0.987442,NO,194,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.396,-5.097,3.701,,0.276,S,b,0.29,0.36,3.593,,67.83,POA,-1.832,0.213352,0.00392163,0.987442 beta-lactamase_156_R189T,beta-lactamase_156_189,TEM-1,beta-lactamase_156,P62593,0.987443,NO,189,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.844,-3.622,1.778,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.111618,0.0050699,0.987443 beta-lactamase_625_D83Q,beta-lactamase_625_83,TEM-1,beta-lactamase_625,P62593,0.987447,NO,83,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.066,-3.681,2.615,,0.354,H,A,0.75,0.22,0.239,,48.95,HAH,-1.34733,0.213352,0.00205968,0.987447 beta-lactamase_39_G243H,beta-lactamase_39_243,TEM-1,beta-lactamase_39,P62593,0.987451,NO,243,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.0495842,0.00464034,0.987451 beta-lactamase_625_L47F,beta-lactamase_625_47,TEM-1,beta-lactamase_625,P62593,0.987453,NO,47,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.876,-3.101,1.225,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.213352,0.00439844,0.987453 beta-lactamase_625_K144T,beta-lactamase_625_144,TEM-1,beta-lactamase_625,P62593,0.987456,NO,144,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-2.388,-2.935,0.547,,0.863,H,A,2.34,1.27,2.313,,77.62,OBA,-1.904,0.213352,0.00481141,0.987456 PSD95pdz3_I377M,PSD95pdz3_377,PSD95pdz3,PSD95pdz3,P31016,0.987456,NO,377,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.873,-3.943,2.07,4.9532,,,,,19.185,2.364,,87.71,HHH,-1.49567,0.0758425,0.000795475,0.987456 beta-lactamase_156_L191Q,beta-lactamase_156_191,TEM-1,beta-lactamase_156,P62593,0.987458,NO,191,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.087,-4.183,3.096,,,H,A,0.55,0.09,1.372,,63.29,BHH,-1.445,0.111618,0.00263549,0.987458 beta-lactamase_156_T158F,beta-lactamase_156_158,TEM-1,beta-lactamase_156,P62593,0.987462,NO,158,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.116,-4.177,3.061,,0.036,,B,0.22,-0.85,3.771,,69.58,HPB,-1.269,0.111618,0.00341825,0.987462 beta-lactamase_39_L136G,beta-lactamase_39_136,TEM-1,beta-lactamase_39,P62593,0.987463,NO,136,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.232,-3.856,2.624,,,H,A,0.55,-0.34,0.336,,48.95,HHH,-1.088,0.0495842,0.00442304,0.987463 beta-lactamase_2500_R118K,beta-lactamase_2500_118,TEM-1,beta-lactamase_2500,P62593,0.987469,NO,118,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.413,-3.492,1.079,,0.457,H,A,1.2,1.39,2.144,,77.62,HBA,-1.785,0.361275,0.00538794,0.987469 beta-lactamase_156_P60W,beta-lactamase_156_60,TEM-1,beta-lactamase_156,P62593,0.987473,NO,60,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-2.469,-5.456,2.987,,0.256,T,A,0.52,-0.56,2.947,,77.62,BOA,-1.97633,0.111618,0.00521318,0.987473 beta-lactamase_0_K109S,beta-lactamase_0_109,TEM-1,beta-lactamase_0,P62593,0.987476,NO,109,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.734,-2.861,1.127,,0.787,G,A,2.34,2.21,15.473,15.473,72.73,ABB,-1.63333,0.0500837,0.00462493,0.987476 beta-lactamase_39_D161C,beta-lactamase_39_161,TEM-1,beta-lactamase_39,P62593,0.987478,NO,161,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.891,-5.1,4.209,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.0495842,0.000897697,0.987478 beta-lactamase_M268L,beta-lactamase_268,TEM-1,beta-lactamase,P62593,0.987479,NO,268,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-2.023,-2.299,0.276,5.4797,0.471,H,A,0.09,0.3,1.071,,65.73,PHA,-2.16233,0.221079,0.0102525,0.987479 beta-lactamase_39_N134Q,beta-lactamase_39_134,TEM-1,beta-lactamase_39,P62593,0.98748,NO,134,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-0.879,-3.672,2.793,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.0495842,0.000644786,0.98748 beta-lactamase_625_I206T,beta-lactamase_625_206,TEM-1,beta-lactamase_625,P62593,0.987484,NO,206,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-2.429,-2.077,-0.352,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.213352,0.00528934,0.987484 beta-lactamase_2500_R202K,beta-lactamase_2500_202,TEM-1,beta-lactamase_2500,P62593,0.987488,NO,202,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.292,-3.005,1.713,,0.188,H,A,1.2,0.62,3.734,,77.62,PBP,-1.54767,0.361275,0.00321899,0.987488 beta-lactamase_39_S96N,beta-lactamase_39_96,TEM-1,beta-lactamase_39,P62593,0.987488,NO,96,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.27,-3.037,0.767,,0.368,,b,0.27,0.39,2.516,,73.78,HPP,-2.019,0.0495842,0.00551835,0.987488 beta-lactamase_2500_G39R,beta-lactamase_2500_39,TEM-1,beta-lactamase_2500,P62593,0.98749,NO,39,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.864,-3.077,1.213,,0.701,T,L,0.29,0.47,29.926,29.926,77.62,HOH,-1.53633,0.361275,0.00487611,0.98749 beta-lactamase_39_A77W,beta-lactamase_39_77,TEM-1,beta-lactamase_39,P62593,0.987491,NO,77,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.234,-5.367,4.133,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.0495842,0.00282362,0.987491 beta-lactamase_156_V101L,beta-lactamase_156_101,TEM-1,beta-lactamase_156,P62593,0.987492,NO,101,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.295,-2.095,0.8,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.111618,0.00374492,0.987492 beta-lactamase_625_D161T,beta-lactamase_625_161,TEM-1,beta-lactamase_625,P62593,0.987503,NO,161,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.891,-3.414,2.523,,0.341,,A,0.75,-0.52,4.655,,61.19,HAB,-0.961333,0.213352,0.000897697,0.987503 beta-lactamase_0_W227F,beta-lactamase_0_227,TEM-1,beta-lactamase_0,P62593,0.987504,NO,227,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-0.982,-2.609,1.627,,0.272,,B,0.47,-0.29,3.782,,74.48,OHH,-1.595,0.0500837,0.00226019,0.987504 beta-lactamase_625_T198V,beta-lactamase_625_198,TEM-1,beta-lactamase_625,P62593,0.987508,NO,198,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.168,-2.827,0.659,,0.489,,B,0.22,-0.13,0.37,,73.78,HPH,-1.98767,0.213352,0.004311,0.987508 beta-lactamase_156_V42T,beta-lactamase_156_42,TEM-1,beta-lactamase_156,P62593,0.987516,NO,42,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.564,-3.48,1.916,,0.017,E,B,0.44,-0.51,2.576,,63.99,BHO,-1.042,0.111618,0.00404515,0.987516 beta-lactamase_625_D99R,beta-lactamase_625_99,TEM-1,beta-lactamase_625,P62593,0.987517,NO,99,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.191,-3.828,2.637,,0.402,G,A,0.75,0.36,1.318,,64.69,PAH,-1.794,0.213352,0.00305446,0.987517 beta-lactamase_156_L135K,beta-lactamase_156_135,TEM-1,beta-lactamase_156,P62593,0.987522,NO,135,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.002,-3.751,2.749,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.111618,0.00244423,0.987522 beta-lactamase_2500_E175P,beta-lactamase_2500_175,TEM-1,beta-lactamase_2500,P62593,0.987529,NO,175,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.336,-1.972,-0.364,,0.551,,A,1.04,1.05,5.316,,77.62,AAB,-1.31233,0.361275,0.00482205,0.987529 beta-lactamase_156_P60V,beta-lactamase_156_60,TEM-1,beta-lactamase_156,P62593,0.987531,NO,60,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-2.469,-3.507,1.038,,0.256,T,A,0.52,-0.56,2.947,,77.62,BOA,-1.97633,0.111618,0.00521318,0.987531 beta-lactamase_39_A170K,beta-lactamase_39_170,TEM-1,beta-lactamase_39,P62593,0.987534,NO,170,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.237,-3.643,2.406,,0.126,,L,0.46,-0.35,3.7,,64.69,AHH,-1.63267,0.0495842,0.00431903,0.987534 beta-lactamase_156_V78A,beta-lactamase_156_78,TEM-1,beta-lactamase_156,P62593,0.987544,NO,78,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.459,-3.121,1.662,,,H,A,0.44,-0.47,1.132,,63.64,HHH,-1.17833,0.111618,0.00492501,0.987544 beta-lactamase_2500_N152V,beta-lactamase_2500_152,TEM-1,beta-lactamase_2500,P62593,0.987547,NO,152,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-2.757,-3.616,0.859,,0.863,H,A,0.61,0.92,2.061,,77.62,BPH,-2.97,0.361275,0.00471429,0.987547 beta-lactamase_2500_S283R,beta-lactamase_2500_283,TEM-1,beta-lactamase_2500,P62593,0.987552,NO,283,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.361275,0.0429138,0.987552 beta-lactamase_625_P105I,beta-lactamase_625_105,TEM-1,beta-lactamase_625,P62593,0.987561,NO,105,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.813,-4.008,3.195,,0.226,T,A,0.52,0.8,1.154,,63.29,POH,-1.01533,0.213352,0.0011981,0.987561 beta-lactamase_2500_R92M,beta-lactamase_2500_92,TEM-1,beta-lactamase_2500,P62593,0.987563,NO,92,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.718,-3.339,1.621,,0.479,E,B,1.2,1.36,3.069,,65.38,BBH,-1.50367,0.361275,0.00429626,0.987563 beta-lactamase_2500_T193S,beta-lactamase_2500_193,TEM-1,beta-lactamase_2500,P62593,0.987567,NO,193,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.914,-2.571,0.657,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.361275,0.00482669,0.987567 beta-lactamase_625_Y103F,beta-lactamase_625_103,TEM-1,beta-lactamase_625,P62593,0.987569,NO,103,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-1.33,-3.391,2.061,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.213352,0.00443048,0.987569 beta-lactamase_39_Q97E,beta-lactamase_39_97,TEM-1,beta-lactamase_39,P62593,0.987571,NO,97,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.072,-2.167,0.095,,0.823,G,A,0.64,2.42,4.457,,77.62,PPP,-2.43833,0.0495842,0.0045116,0.987571 beta-lactamase_156_L197Y,beta-lactamase_156_197,TEM-1,beta-lactamase_156,P62593,0.98758,NO,197,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.853,-3.986,3.133,,0.007,S,B,0.55,0.33,1.58,,60.14,HHP,-1.833,0.111618,0.00144602,0.98758 beta-lactamase_625_A123C,beta-lactamase_625_123,TEM-1,beta-lactamase_625,P62593,0.987581,NO,123,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.834,-4.461,3.627,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.213352,0.0010157,0.987581 beta-lactamase_2500_E169R,beta-lactamase_2500_169,TEM-1,beta-lactamase_2500,P62593,0.987589,NO,169,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.23,-3.638,2.408,,0.337,,A,1.04,1,1.806,,73.08,PAH,-1.16533,0.361275,0.00400994,0.987589 beta-lactamase_L74L,beta-lactamase_74,TEM-1,beta-lactamase,P62593,0.987591,NO,74,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.296,-1.296,,5.50288,,H,A,1.75,-0.91,1.581,,50,HHO,-1.34933,0.221079,0.00493255,0.987591 beta-lactamase_39_A278D,beta-lactamase_39_278,TEM-1,beta-lactamase_39,P62593,0.987593,NO,278,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.0495842,0.0310297,0.987593 beta-lactamase_39_G85T,beta-lactamase_39_85,TEM-1,beta-lactamase_39,P62593,0.987593,NO,85,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.011,-3.637,2.626,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.0495842,0.00252173,0.987593 beta-lactamase_156_H156V,beta-lactamase_156_156,TEM-1,beta-lactamase_156,P62593,0.987597,NO,156,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-3.156,-3.735,0.579,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.111618,0.00468596,0.987597 beta-lactamase_156_I125A,beta-lactamase_156_125,TEM-1,beta-lactamase_156,P62593,0.987597,NO,125,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.441,-3.138,1.697,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.111618,0.00383964,0.987597 beta-lactamase_625_Q204A,beta-lactamase_625_204,TEM-1,beta-lactamase_625,P62593,0.987603,NO,204,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-1.382,-2.589,1.207,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.213352,0.00364106,0.987603 beta-lactamase_39_N98C,beta-lactamase_39_98,TEM-1,beta-lactamase_39,P62593,0.987607,NO,98,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-2.973,-5.105,2.132,,0.963,G,A,0.61,1.35,14.853,14.853,77.62,PPA,-2.07867,0.0495842,0.00505389,0.987607 beta-lactamase_39_G253L,beta-lactamase_39_253,TEM-1,beta-lactamase_39,P62593,0.98761,NO,253,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.0495842,0.00786358,0.98761 beta-lactamase_625_H94N,beta-lactamase_625_94,TEM-1,beta-lactamase_625,P62593,0.987612,NO,94,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-2.5,-3.811,1.311,,0.776,,B,0.17,1.24,19.42,19.42,77.62,HBH,-1.872,0.213352,0.00389226,0.987612 beta-lactamase_2500_K53V,beta-lactamase_2500_53,TEM-1,beta-lactamase_2500,P62593,0.987614,NO,53,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-2.313,-3.678,1.365,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.361275,0.00383383,0.987614 beta-lactamase_2500_N50Y,beta-lactamase_2500_50,TEM-1,beta-lactamase_2500,P62593,0.987614,NO,50,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-2.979,-4.3,1.321,,0.912,T,A,0.61,1.24,1.581,,77.62,HPP,-2.134,0.361275,0.0047211,0.987614 beta-lactamase_39_I54R,beta-lactamase_39_54,TEM-1,beta-lactamase_39,P62593,0.987618,NO,54,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-2.838,-2.365,-0.473,,0.669,E,B,0.48,-0.14,1.349,,73.78,BHH,-2.337,0.0495842,0.00403589,0.987618 beta-lactamase_F22S,beta-lactamase_22,TEM-1,beta-lactamase,P62593,0.987621,NO,22,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-2.676,-3.543,0.867,,,,,,,1.616,,73.08,HHH,-2.03233,0.221079,0.00262842,0.987621 beta-lactamase_G226T,beta-lactamase_226,TEM-1,beta-lactamase,P62593,0.987621,NO,226,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.461,-3.599,2.138,5.70682,0.701,T,l,0.77,-0.25,3.199,,74.48,HOH,-1.42933,0.221079,0.00665294,0.987621 beta-lactamase_K190Q,beta-lactamase_190,TEM-1,beta-lactamase,P62593,0.987621,NO,190,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.994,-2.883,0.889,5.49163,0.371,H,A,1.82,0.16,29.753,29.753,77.62,BBH,-1.64167,0.221079,0.00574527,0.987621 beta-lactamase_P20E,beta-lactamase_20,TEM-1,beta-lactamase,P62593,0.987621,NO,20,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.74,-3.486,1.746,,,,,,,0.368,,67.83,HOH,-1.765,0.221079,0.00235322,0.987621 beta-lactamase_39_K32D,beta-lactamase_39_32,TEM-1,beta-lactamase_39,P62593,0.987632,NO,32,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.984,-2.882,0.898,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.0495842,0.00401283,0.987632 beta-lactamase_625_F228S,beta-lactamase_625_228,TEM-1,beta-lactamase_625,P62593,0.987632,NO,228,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-2.342,-3.492,1.15,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.213352,0.0046669,0.987632 beta-lactamase_39_R176G,beta-lactamase_39_176,TEM-1,beta-lactamase_39,P62593,0.987635,NO,176,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-0.863,-3.358,2.495,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.0495842,0.00105554,0.987635 beta-lactamase_156_M67I,beta-lactamase_156_67,TEM-1,beta-lactamase_156,P62593,0.98764,NO,67,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-2.231,-2.93,0.699,,0.006,G,P,0.55,-0.81,1.463,,65.03,HHP,-1.502,0.111618,0.00409753,0.98764 beta-lactamase_39_K53E,beta-lactamase_39_53,TEM-1,beta-lactamase_39,P62593,0.987645,NO,53,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-2.313,-2.655,0.342,,0.589,,B,2.34,1.15,15.633,15.633,77.62,OBH,-2.1,0.0495842,0.00383383,0.987645 beta-lactamase_156_E175H,beta-lactamase_156_175,TEM-1,beta-lactamase_156,P62593,0.987648,NO,175,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.336,-3.355,1.019,,0.551,,A,1.04,1.05,2.334,,77.62,AAB,-1.31233,0.111618,0.00482205,0.987648 beta-lactamase_2500_K30T,beta-lactamase_2500_30,TEM-1,beta-lactamase_2500,P62593,0.987648,NO,30,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-2.307,-2.199,-0.108,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.361275,0.00448593,0.987648 beta-lactamase_2500_K286R,beta-lactamase_2500_286,TEM-1,beta-lactamase_2500,P62593,0.987653,NO,286,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.361275,,0.987653 beta-lactamase_625_L111Y,beta-lactamase_625_111,TEM-1,beta-lactamase_625,P62593,0.987654,NO,111,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.76,-4.039,2.279,,0.328,T,A,0.55,0.93,2.26,,64.34,BHP,-1.884,0.213352,0.00480671,0.987654 beta-lactamase_156_L199M,beta-lactamase_156_199,TEM-1,beta-lactamase_156,P62593,0.987657,NO,199,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-2.942,-4.728,1.786,,0.832,H,A,0.55,0.42,1.552,,77.62,PHH,-2.32933,0.111618,0.0048649,0.987657 beta-lactamase_625_K254Y,beta-lactamase_625_254,TEM-1,beta-lactamase_625,P62593,0.987667,NO,254,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.213352,0.00369,0.987667 beta-lactamase_156_I229F,beta-lactamase_156_229,TEM-1,beta-lactamase_156,P62593,0.987675,NO,229,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.267,-3.792,2.525,,0.083,E,B,0.48,-0.76,1.114,,50,HHH,-1.58767,0.111618,0.00477249,0.987675 beta-lactamase_0_G226S,beta-lactamase_0_226,TEM-1,beta-lactamase_0,P62593,0.987684,NO,226,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.461,-2.74,1.279,,0.701,T,l,0.29,-0.25,23.034,23.034,74.48,HOH,-1.42933,0.0500837,0.00665294,0.987684 beta-lactamase_39_Y262Q,beta-lactamase_39_262,TEM-1,beta-lactamase_39,P62593,0.987684,NO,262,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.0495842,0.00853516,0.987684 beta-lactamase_2500_Q204V,beta-lactamase_2500_204,TEM-1,beta-lactamase_2500,P62593,0.987688,NO,204,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-1.382,-3.595,2.213,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.361275,0.00364106,0.987688 beta-lactamase_625_D99G,beta-lactamase_625_99,TEM-1,beta-lactamase_625,P62593,0.98769,NO,99,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.191,-3.32,2.129,,0.402,G,A,0.75,0.36,1.318,,64.69,PAH,-1.794,0.213352,0.00305446,0.98769 beta-lactamase_A266E,beta-lactamase_266,TEM-1,beta-lactamase,P62593,0.987693,NO,266,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.369,-3.593,2.224,5.02057,0.175,S,B,0.52,0.07,1.832,,64.34,PHP,-2.08567,0.221079,0.0140785,0.987693 beta-lactamase_156_E175C,beta-lactamase_156_175,TEM-1,beta-lactamase_156,P62593,0.987694,NO,175,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.336,-5.076,2.74,,0.551,,A,1.04,1.05,2.334,,77.62,AAB,-1.31233,0.111618,0.00482205,0.987694 beta-lactamase_39_L73T,beta-lactamase_39_73,TEM-1,beta-lactamase_39,P62593,0.987695,NO,73,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.507,-3.582,2.075,,,H,A,0.55,-0.64,2.09,,67.83,HHH,-1.487,0.0495842,0.00488983,0.987695 beta-lactamase_625_G39I,beta-lactamase_625_39,TEM-1,beta-lactamase_625,P62593,0.987697,NO,39,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.864,-4.195,2.331,,0.701,T,L,0.29,0.47,29.926,29.926,77.62,HOH,-1.53633,0.213352,0.00487611,0.987697 kka2_1:8_P76V,kka2_1:8_76,Kka2,kka2_1:8,P00552,0.987698,NO,76,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.449,-2.929,1.48,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.100394,0.00625685,0.987698 kka2_1:8_P76V,kka2_1:8_76,Kka2,kka2_1:8,P00552,0.987698,NO,76,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.449,-2.929,1.48,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.100394,0.00625685,0.987698 beta-lactamase_156_P255F,beta-lactamase_156_255,TEM-1,beta-lactamase_156,P62593,0.987707,NO,255,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.111618,0.00499612,0.987707 beta-lactamase_156_T178I,beta-lactamase_156_178,TEM-1,beta-lactamase_156,P62593,0.987711,NO,178,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-0.791,-3.56,2.769,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.111618,0.000684366,0.987711 beta-lactamase_2500_G39D,beta-lactamase_2500_39,TEM-1,beta-lactamase_2500,P62593,0.987713,NO,39,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.864,-2.194,0.33,,0.701,T,L,0.29,0.47,29.926,29.926,77.62,HOH,-1.53633,0.361275,0.00487611,0.987713 beta-lactamase_39_A222Y,beta-lactamase_39_222,TEM-1,beta-lactamase_39,P62593,0.987715,NO,222,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.103,-4.186,2.083,,0.233,H,A,0.46,-0.25,1.448,,77.62,PHH,-1.63733,0.0495842,0.00466094,0.987715 beta-lactamase_625_D207E,beta-lactamase_625_207,TEM-1,beta-lactamase_625,P62593,0.987723,NO,207,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.064,-2.615,0.551,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.213352,0.00592942,0.987723 Pab1_N187D,Pab1_187,Pab1,Pab1,P04147,0.987732,NO,187,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-1.224,-1.959,0.735,,0.456,S,b,,1.87,,,,HPO,-1.272,0.175299,0.00083165,0.987732 beta-lactamase_625_I140Y,beta-lactamase_625_140,TEM-1,beta-lactamase_625,P62593,0.987733,NO,140,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.733,-3.996,2.263,,0.128,H,A,0.48,0.41,1.628,,73.08,PHO,-1.48733,0.213352,0.00597777,0.987733 beta-lactamase_39_E61D,beta-lactamase_39_61,TEM-1,beta-lactamase_39,P62593,0.987742,NO,61,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.115,-1.402,-0.713,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.0495842,0.00440955,0.987742 beta-lactamase_156_D113V,beta-lactamase_156_113,TEM-1,beta-lactamase_156,P62593,0.987745,NO,113,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.829,-3.01,1.181,,0.665,T,A,0.75,0.91,2.973,,73.08,PAO,-1.703,0.111618,0.00474112,0.987745 beta-lactamase_156_R162D,beta-lactamase_156_162,TEM-1,beta-lactamase_156,P62593,0.987747,NO,162,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.016,-3.754,2.738,,0.124,S,B,1.2,-0.37,7.444,,64.69,ABH,-1.25,0.111618,0.000561334,0.987747 beta-lactamase_39_T264W,beta-lactamase_39_264,TEM-1,beta-lactamase_39,P62593,0.987749,NO,264,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.0495842,0.0119399,0.987749 beta-lactamase_39_E56F,beta-lactamase_39_56,TEM-1,beta-lactamase_39,P62593,0.987751,NO,56,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.043,-4.191,2.148,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.0495842,0.00238534,0.987751 beta-lactamase_156_D231G,beta-lactamase_156_231,TEM-1,beta-lactamase_156,P62593,0.987759,NO,231,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.816,-3.182,2.366,,,E,B,0.75,-1.06,2.66,,65.38,HAB,-0.994,0.111618,0.00107395,0.987759 PSD95pdz3_G356R,PSD95pdz3_356,PSD95pdz3,PSD95pdz3,P31016,0.987765,NO,356,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.008,-3.615,2.607,4.8656,,,,,11.9575,,,,BOA,-1.22933,0.0758425,0.000623061,0.987765 beta-lactamase_I283V,beta-lactamase_283,TEM-1,beta-lactamase,P62593,0.98777,NO,283,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.638,-1.617,-0.021,5.4178,0.165,H,A,1.23,0.04,1.576,,69.23,HHB,-1.735,0.221079,0.0429138,0.98777 beta-lactamase_0_G249F,beta-lactamase_0_249,TEM-1,beta-lactamase_0,P62593,0.987776,NO,249,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.0500837,0.00220169,0.987776 beta-lactamase_156_Q97L,beta-lactamase_156_97,TEM-1,beta-lactamase_156,P62593,0.98778,NO,97,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.072,-3.528,1.456,,0.823,G,A,0.64,2.42,4.457,,77.62,PPP,-2.43833,0.111618,0.0045116,0.98778 beta-lactamase_156_L196K,beta-lactamase_156_196,TEM-1,beta-lactamase_156,P62593,0.987795,NO,196,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-2.478,-3.633,1.155,,0.518,S,A,0.55,1.35,7.897,,77.62,AHH,-1.839,0.111618,0.00512144,0.987795 beta-lactamase_625_G76M,beta-lactamase_625_76,TEM-1,beta-lactamase_625,P62593,0.987795,NO,76,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.189,-4.767,3.578,,,H,A,0.29,-0.67,3.059,,67.83,OOH,-1.22267,0.213352,0.00476637,0.987795 beta-lactamase_156_S122W,beta-lactamase_156_122,TEM-1,beta-lactamase_156,P62593,0.987796,NO,122,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.406,-5.469,3.063,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.111618,0.00497825,0.987796 beta-lactamase_39_L73I,beta-lactamase_39_73,TEM-1,beta-lactamase_39,P62593,0.987803,NO,73,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.507,-2.52,1.013,,,H,A,0.55,-0.64,2.09,,67.83,HHH,-1.487,0.0495842,0.00488983,0.987803 Pab1_L133V,Pab1_133,Pab1,Pab1,P04147,0.987803,NO,133,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.039,-2.671,1.632,,0.015,,B,1.75,1.03,,,,PHB,-1.22,0.175299,0.000345939,0.987803 beta-lactamase_156_N50V,beta-lactamase_156_50,TEM-1,beta-lactamase_156,P62593,0.987804,NO,50,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-2.979,-2.913,-0.066,,0.912,T,A,0.61,1.24,13.295,13.295,77.62,HPP,-2.134,0.111618,0.0047211,0.987804 beta-lactamase_625_L111P,beta-lactamase_625_111,TEM-1,beta-lactamase_625,P62593,0.987809,NO,111,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.76,-4.076,2.316,,0.328,T,A,0.55,0.93,2.26,,64.34,BHP,-1.884,0.213352,0.00480671,0.987809 beta-lactamase_625_F149A,beta-lactamase_625_149,TEM-1,beta-lactamase_625,P62593,0.987813,NO,149,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.299,-3.341,2.042,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.213352,0.00418462,0.987813 beta-lactamase_156_E169C,beta-lactamase_156_169,TEM-1,beta-lactamase_156,P62593,0.987815,NO,169,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.23,-5.088,3.858,,0.337,,A,1.04,1,3.516,,73.08,PAH,-1.16533,0.111618,0.00400994,0.987815 beta-lactamase_625_A247C,beta-lactamase_625_247,TEM-1,beta-lactamase_625,P62593,0.987815,NO,247,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.213352,0.00611275,0.987815 beta-lactamase_156_K190P,beta-lactamase_156_190,TEM-1,beta-lactamase_156,P62593,0.987821,NO,190,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.994,-3.086,1.092,,0.371,H,A,2.34,0.16,1.513,,77.62,BBH,-1.64167,0.111618,0.00574527,0.987821 beta-lactamase_625_T269E,beta-lactamase_625_269,TEM-1,beta-lactamase_625,P62593,0.987825,NO,269,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.213352,0.00950944,0.987825 beta-lactamase_39_H94L,beta-lactamase_39_94,TEM-1,beta-lactamase_39,P62593,0.987831,NO,94,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-2.5,-3.441,0.941,,0.776,,B,0.17,1.24,11.583,11.583,77.62,HBH,-1.872,0.0495842,0.00389226,0.987831 beta-lactamase_156_G226T,beta-lactamase_156_226,TEM-1,beta-lactamase_156,P62593,0.987836,NO,226,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.461,-3.599,2.138,,0.701,T,l,0.29,-0.25,3.199,,74.48,HOH,-1.42933,0.111618,0.00665294,0.987836 beta-lactamase_39_T263W,beta-lactamase_39_263,TEM-1,beta-lactamase_39,P62593,0.987836,NO,263,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.0495842,0.0110582,0.987836 beta-lactamase_39_N98V,beta-lactamase_39_98,TEM-1,beta-lactamase_39,P62593,0.987839,NO,98,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-2.973,-3.696,0.723,,0.963,G,A,0.61,1.35,14.853,14.853,77.62,PPA,-2.07867,0.0495842,0.00505389,0.987839 beta-lactamase_156_S266Q,beta-lactamase_156_266,TEM-1,beta-lactamase_156,P62593,0.987844,NO,266,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.111618,0.0140785,0.987844 beta-lactamase_E145V,beta-lactamase_145,TEM-1,beta-lactamase,P62593,0.987844,NO,145,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.357,-3.665,1.308,5.38104,0.545,H,A,0.52,0.79,2.124,,77.62,BAH,-2.069,0.221079,0.00553285,0.987844 beta-lactamase_156_T138F,beta-lactamase_156_138,TEM-1,beta-lactamase_156,P62593,0.987845,NO,138,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.506,-4.444,1.938,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.111618,0.00487868,0.987845 beta-lactamase_156_A123Y,beta-lactamase_156_123,TEM-1,beta-lactamase_156,P62593,0.987849,NO,123,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.834,-4.16,3.326,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.111618,0.0010157,0.987849 beta-lactamase_625_H24Y,beta-lactamase_625_24,TEM-1,beta-lactamase_625,P62593,0.987851,NO,24,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-2.481,-4.052,1.571,,,,,,,2.708,,93.01,OBO,-2.0035,0.213352,0.00238894,0.987851 beta-lactamase_H5Q,beta-lactamase_5,TEM-1,beta-lactamase,P62593,0.987853,NO,5,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-2.698,-3.911,1.213,,,,,,,1.865,,72.73,PBH,-2.36967,0.221079,0.00292712,0.987853 Pab1_E195A,Pab1_195,Pab1,Pab1,P04147,0.987856,NO,195,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.2,-2.948,1.748,,,,,,,,,,PAH,-1.72467,0.175299,0.000620107,0.987856 beta-lactamase_156_T263C,beta-lactamase_156_263,TEM-1,beta-lactamase_156,P62593,0.987858,NO,263,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.111618,0.0110582,0.987858 beta-lactamase_0_T178C,beta-lactamase_0_178,TEM-1,beta-lactamase_0,P62593,0.987859,NO,178,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-0.791,-4.637,3.846,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.0500837,0.000684366,0.987859 beta-lactamase_2500_D271S,beta-lactamase_2500_271,TEM-1,beta-lactamase_2500,P62593,0.987862,NO,271,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.361275,0.00752082,0.987862 kka2_1:4_G164Y,kka2_1:4_164,Kka2,kka2_1:4,P00552,0.987867,NO,164,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.869,-4.442,3.573,,0.862,T,l,0.75,1.45,1.539,,64.39,POH,-1.828,0.168804,0.00442091,0.987867 beta-lactamase_625_G253S,beta-lactamase_625_253,TEM-1,beta-lactamase_625,P62593,0.987868,NO,253,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.213352,0.00786358,0.987868 beta-lactamase_156_K53C,beta-lactamase_156_53,TEM-1,beta-lactamase_156,P62593,0.987872,NO,53,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-2.313,-5.135,2.822,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.111618,0.00383383,0.987872 kka2_1:1_R177G,kka2_1:1_177,Kka2,kka2_1:1,P00552,0.987881,NO,177,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.282,-2.48,0.198,,0.521,T,A,1.2,0.16,1.842,,63.64,HBH,-2.36967,0.520039,0.00768224,0.987881 beta-lactamase_39_K254Y,beta-lactamase_39_254,TEM-1,beta-lactamase_39,P62593,0.987883,NO,254,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.0495842,0.00369,0.987883 beta-lactamase_39_D83H,beta-lactamase_39_83,TEM-1,beta-lactamase_39,P62593,0.987885,NO,83,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.066,-4.503,3.437,,0.354,H,A,0.75,0.22,0.752,,48.95,HAH,-1.34733,0.0495842,0.00205968,0.987885 beta-lactamase_39_W227T,beta-lactamase_39_227,TEM-1,beta-lactamase_39,P62593,0.987894,NO,227,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-0.982,-3.696,2.714,,0.272,,B,0.47,-0.29,1.37,,74.48,OHH,-1.595,0.0495842,0.00226019,0.987894 beta-lactamase_0_T178S,beta-lactamase_0_178,TEM-1,beta-lactamase_0,P62593,0.987896,NO,178,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-0.791,-2.936,2.145,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.0500837,0.000684366,0.987896 beta-lactamase_39_A77R,beta-lactamase_39_77,TEM-1,beta-lactamase_39,P62593,0.987898,NO,77,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.234,-3.891,2.657,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.0495842,0.00282362,0.987898 beta-lactamase_625_E56Q,beta-lactamase_625_56,TEM-1,beta-lactamase_625,P62593,0.987899,NO,56,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.043,-3.697,1.654,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.213352,0.00238534,0.987899 beta-lactamase_2500_V106E,beta-lactamase_2500_106,TEM-1,beta-lactamase_2500,P62593,0.987902,NO,106,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.218,-3.859,2.641,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.361275,0.00304168,0.987902 beta-lactamase_156_E56R,beta-lactamase_156_56,TEM-1,beta-lactamase_156,P62593,0.987908,NO,56,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.043,-3.679,1.636,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.111618,0.00238534,0.987908 beta-lactamase_625_Q204W,beta-lactamase_625_204,TEM-1,beta-lactamase_625,P62593,0.987912,NO,204,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-1.382,-5.303,3.921,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.213352,0.00364106,0.987912 beta-lactamase_A84R,beta-lactamase_84,TEM-1,beta-lactamase,P62593,0.987912,NO,84,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.651,-2.603,0.952,5.28927,0.65,T,A,0.52,0.96,1.863,,68.18,AHO,-1.24267,0.221079,0.00503822,0.987912 beta-lactamase_S96Q,beta-lactamase_96,TEM-1,beta-lactamase,P62593,0.987912,NO,96,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.27,-2.919,0.649,5.29889,0.368,,b,0.25,0.39,32.348,32.348,73.78,HPP,-2.019,0.221079,0.00551835,0.987912 beta-lactamase_625_I171D,beta-lactamase_625_171,TEM-1,beta-lactamase_625,P62593,0.987914,NO,171,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-2.431,-3.888,1.457,,0.361,,B,0.48,0.53,3.869,,77.62,HHO,-1.55533,0.213352,0.00623355,0.987914 beta-lactamase_0_L135S,beta-lactamase_0_135,TEM-1,beta-lactamase_0,P62593,0.98792,NO,135,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.002,-3.64,2.638,,0.117,H,A,0.55,-0.58,0.705,,43.71,PHH,-1.03767,0.0500837,0.00244423,0.98792 beta-lactamase_2500_Y44F,beta-lactamase_2500_44,TEM-1,beta-lactamase_2500,P62593,0.987922,NO,44,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-2.547,-2.714,0.167,,,E,B,0.21,-0.45,2.184,,73.78,OHH,-1.86267,0.361275,0.00426364,0.987922 beta-lactamase_39_R273Y,beta-lactamase_39_273,TEM-1,beta-lactamase_39,P62593,0.987932,NO,273,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.314,-4.336,2.022,,0.564,H,A,1.2,1.57,2.163,,73.78,ABP,-1.841,0.0495842,0.0077952,0.987932 beta-lactamase_39_I206A,beta-lactamase_39_206,TEM-1,beta-lactamase_39,P62593,0.987947,NO,206,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-2.429,-2.387,-0.042,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.0495842,0.00528934,0.987947 PSD95pdz3_G383P,PSD95pdz3_383,PSD95pdz3,PSD95pdz3,P31016,0.987948,NO,383,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.008,-3.561,2.553,5.17213,,,,,20.5325,,,,HOP,-1.338,0.0758425,0.000233044,0.987948 beta-lactamase_156_Q267M,beta-lactamase_156_267,TEM-1,beta-lactamase_156,P62593,0.987949,NO,267,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.111618,0.0102128,0.987949 beta-lactamase_156_D231V,beta-lactamase_156_231,TEM-1,beta-lactamase_156,P62593,0.987954,NO,231,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.816,-3.751,2.935,,,E,B,0.75,-1.06,2.66,,65.38,HAB,-0.994,0.111618,0.00107395,0.987954 beta-lactamase_39_H151P,beta-lactamase_39_151,TEM-1,beta-lactamase_39,P62593,0.987955,NO,151,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-2.96,-3.911,0.951,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.0495842,0.00216946,0.987955 beta-lactamase_39_D207M,beta-lactamase_39_207,TEM-1,beta-lactamase_39,P62593,0.98796,NO,207,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.064,-4.822,2.758,,0.409,H,A,0.75,0.12,14.511,14.511,77.62,HAH,-1.77033,0.0495842,0.00592942,0.98796 beta-lactamase_625_L188T,beta-lactamase_625_188,TEM-1,beta-lactamase_625,P62593,0.987963,NO,188,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.166,-3.522,2.356,,,H,A,0.55,-0.3,2.982,,60.14,PHB,-1.47033,0.213352,0.00295687,0.987963 beta-lactamase_156_G265M,beta-lactamase_156_265,TEM-1,beta-lactamase_156,P62593,0.987967,NO,265,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.111618,0.00811926,0.987967 beta-lactamase_625_G253Q,beta-lactamase_625_253,TEM-1,beta-lactamase_625,P62593,0.987971,NO,253,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.213352,0.00786358,0.987971 beta-lactamase_39_N152D,beta-lactamase_39_152,TEM-1,beta-lactamase_39,P62593,0.987982,NO,152,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-2.757,-3.573,0.816,,0.863,H,A,0.61,0.92,4.038,,77.62,BPH,-2.97,0.0495842,0.00471429,0.987982 beta-lactamase_156_V78S,beta-lactamase_156_78,TEM-1,beta-lactamase_156,P62593,0.987984,NO,78,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.459,-3.701,2.242,,,H,A,0.44,-0.47,1.132,,63.64,HHH,-1.17833,0.111618,0.00492501,0.987984 beta-lactamase_156_W208C,beta-lactamase_156_208,TEM-1,beta-lactamase_156,P62593,0.987985,NO,208,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-0.818,-4.862,4.044,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.111618,0.00126609,0.987985 beta-lactamase_156_L47H,beta-lactamase_156_47,TEM-1,beta-lactamase_156,P62593,0.987986,NO,47,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.876,-2.811,0.935,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.111618,0.00439844,0.987986 beta-lactamase_156_L79F,beta-lactamase_156_79,TEM-1,beta-lactamase_156,P62593,0.987986,NO,79,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.842,-3.643,2.801,,0.007,H,A,0.55,-0.16,1.831,,50.35,HHP,-1.44333,0.111618,0.000947397,0.987986 beta-lactamase_156_I206S,beta-lactamase_156_206,TEM-1,beta-lactamase_156,P62593,0.987988,NO,206,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-2.429,-3.468,1.039,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.111618,0.00528934,0.987988 beta-lactamase_2500_V106L,beta-lactamase_2500_106,TEM-1,beta-lactamase_2500,P62593,0.987988,NO,106,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.218,-2.154,0.936,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.361275,0.00304168,0.987988 beta-lactamase_39_A246L,beta-lactamase_39_246,TEM-1,beta-lactamase_39,P62593,0.98799,NO,246,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.121,-1.908,-0.213,,0.01,E,B,0.46,-1.01,1.331,,73.78,HHH,-1.55633,0.0495842,0.00569458,0.98799 beta-lactamase_39_S283V,beta-lactamase_39_283,TEM-1,beta-lactamase_39,P62593,0.987992,NO,283,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.0495842,0.0429138,0.987992 beta-lactamase_156_R257H,beta-lactamase_156_257,TEM-1,beta-lactamase_156,P62593,0.987998,NO,257,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.111618,0.00756629,0.987998 beta-lactamase_156_S266T,beta-lactamase_156_266,TEM-1,beta-lactamase_156,P62593,0.987998,NO,266,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.111618,0.0140785,0.987998 beta-lactamase_39_H287V,beta-lactamase_39_287,TEM-1,beta-lactamase_39,P62593,0.987999,NO,287,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,,,,,,,,,,,,,BBH,-1.111,0.0495842,,0.987999 beta-lactamase_625_S57I,beta-lactamase_625_57,TEM-1,beta-lactamase_625,P62593,0.988001,NO,57,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.918,-3.825,1.907,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.213352,0.00492804,0.988001 beta-lactamase_625_V101N,beta-lactamase_625_101,TEM-1,beta-lactamase_625,P62593,0.988002,NO,101,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.295,-4.085,2.79,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.213352,0.00374492,0.988002 beta-lactamase_625_N98P,beta-lactamase_625_98,TEM-1,beta-lactamase_625,P62593,0.988006,NO,98,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-2.973,-3.946,0.973,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.213352,0.00505389,0.988006 beta-lactamase_39_V82T,beta-lactamase_39_82,TEM-1,beta-lactamase_39,P62593,0.988009,NO,82,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.325,-3.392,2.067,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.0495842,0.00397046,0.988009 beta-lactamase_G43G,beta-lactamase_43,TEM-1,beta-lactamase,P62593,0.988011,NO,43,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.62,-0.62,,5.28886,,E,B,0.77,-0.78,,,,HOH,-1.577,0.221079,0.00120151,0.988011 beta-lactamase_156_R91F,beta-lactamase_156_91,TEM-1,beta-lactamase_156,P62593,0.988012,NO,91,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.392,-4.376,2.984,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.111618,0.00380226,0.988012 beta-lactamase_2500_L160I,beta-lactamase_2500_160,TEM-1,beta-lactamase_2500,P62593,0.988015,NO,160,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.977,-2.155,1.178,,0.022,,B,0.55,-0.6,0.895,,44.41,BHA,-0.936,0.361275,0.00193775,0.988015 beta-lactamase_625_K144C,beta-lactamase_625_144,TEM-1,beta-lactamase_625,P62593,0.988015,NO,144,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-2.388,-5.107,2.719,,0.863,H,A,2.34,1.27,2.313,,77.62,OBA,-1.904,0.213352,0.00481141,0.988015 beta-lactamase_156_G216T,beta-lactamase_156_216,TEM-1,beta-lactamase_156,P62593,0.988016,NO,216,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.477,-3.599,2.122,,0.437,I,A,0.29,-0.58,12.464,12.464,74.48,HOO,-1.68067,0.111618,0.00639568,0.988016 beta-lactamase_156_G253Q,beta-lactamase_156_253,TEM-1,beta-lactamase_156,P62593,0.988023,NO,253,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.111618,0.00786358,0.988023 PSD95pdz3_E352V,PSD95pdz3_352,PSD95pdz3,PSD95pdz3,P31016,0.988024,NO,352,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.587,-3.101,1.514,5.49659,,,,,24.2,2.525,,86.88,OAH,-1.314,0.0758425,0.000892231,0.988024 beta-lactamase_39_R257A,beta-lactamase_39_257,TEM-1,beta-lactamase_39,P62593,0.988025,NO,257,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.0495842,0.00756629,0.988025 beta-lactamase_39_P250V,beta-lactamase_39_250,TEM-1,beta-lactamase_39,P62593,0.988028,NO,250,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.0495842,0.00550899,0.988028 beta-lactamase_625_K254S,beta-lactamase_625_254,TEM-1,beta-lactamase_625,P62593,0.988029,NO,254,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-2.126,-3.446,1.32,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.213352,0.00369,0.988029 kka2_1:2_H139N,kka2_1:2_139,Kka2,kka2_1:2,P00552,0.98803,NO,139,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-2.809,-2.773,-0.036,,0.471,H,A,0.87,0.68,13.912,13.912,63.64,BBB,-2.22,0.295029,0.00734779,0.98803 beta-lactamase_V31V,beta-lactamase_31,TEM-1,beta-lactamase,P62593,0.98804,NO,31,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.822,-1.822,,5.43781,,H,A,2.78,-0.46,2.885,,73.78,BHB,-2.03767,0.221079,0.00478065,0.98804 beta-lactamase_2500_D271T,beta-lactamase_2500_271,TEM-1,beta-lactamase_2500,P62593,0.988052,NO,271,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.361275,0.00752082,0.988052 beta-lactamase_625_S51H,beta-lactamase_625_51,TEM-1,beta-lactamase_625,P62593,0.988052,NO,51,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.526,-4.622,3.096,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.213352,0.00504821,0.988052 beta-lactamase_625_T147S,beta-lactamase_625_147,TEM-1,beta-lactamase_625,P62593,0.98806,NO,147,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.149,-2.487,1.338,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.213352,0.00226017,0.98806 beta-lactamase_2500_N98W,beta-lactamase_2500_98,TEM-1,beta-lactamase_2500,P62593,0.988064,NO,98,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-2.973,-5.455,2.482,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.361275,0.00505389,0.988064 beta-lactamase_2500_T139L,beta-lactamase_2500_139,TEM-1,beta-lactamase_2500,P62593,0.988069,NO,139,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.901,-3.419,1.518,,0.216,H,A,0.22,0.39,2.256,,77.62,PPH,-2.04667,0.361275,0.00441837,0.988069 beta-lactamase_39_V29K,beta-lactamase_39_29,TEM-1,beta-lactamase_39,P62593,0.988069,NO,29,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-2.856,-2.195,-0.661,,0.733,H,A,0.44,-0.78,1.287,,93.01,HHB,-2.24733,0.0495842,0.00318969,0.988069 beta-lactamase_625_G216Y,beta-lactamase_625_216,TEM-1,beta-lactamase_625,P62593,0.98807,NO,216,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.477,-4.44,2.963,,0.437,I,A,0.29,-0.58,1.718,,74.48,HOO,-1.68067,0.213352,0.00639568,0.98807 PSD95pdz3_S371G,PSD95pdz3_371,PSD95pdz3,PSD95pdz3,P31016,0.988088,NO,371,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.86,-2.93,1.07,5.19744,,,,,17.1117,3.854,,87.71,HPB,-1.598,0.0758425,0.000847873,0.988088 beta-lactamase_156_V214L,beta-lactamase_156_214,TEM-1,beta-lactamase_156,P62593,0.98809,NO,214,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.299,-2.237,0.938,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.111618,0.00628442,0.98809 beta-lactamase_D113Q,beta-lactamase_113,TEM-1,beta-lactamase,P62593,0.988091,NO,113,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.829,-2.873,1.044,6.04499,0.665,T,A,0.23,0.91,21.104,21.104,73.08,PAO,-1.703,0.221079,0.00474112,0.988091 beta-lactamase_39_T269Y,beta-lactamase_39_269,TEM-1,beta-lactamase_39,P62593,0.988092,NO,269,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.156,,,,0.646,H,A,0.53,0.4,3.889,,77.62,HPH,-1.96733,0.0495842,0.00950944,0.988092 beta-lactamase_0_A34E,beta-lactamase_0_34,TEM-1,beta-lactamase_0,P62593,0.988094,NO,34,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.059,-3.743,1.684,,,H,A,0.46,-0.54,3.998,,73.78,AHA,-1.74967,0.0500837,0.00407913,0.988094 beta-lactamase_2500_S57K,beta-lactamase_2500_57,TEM-1,beta-lactamase_2500,P62593,0.988108,NO,57,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.918,-3.565,1.647,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.361275,0.00492804,0.988108 beta-lactamase_39_A183D,beta-lactamase_39_183,TEM-1,beta-lactamase_39,P62593,0.988116,NO,183,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.231,-2.686,1.455,,0.155,H,A,0.46,-0.91,1.237,,77.62,HHH,-1.53367,0.0495842,0.00296631,0.988116 beta-lactamase_625_G154H,beta-lactamase_625_154,TEM-1,beta-lactamase_625,P62593,0.988118,NO,154,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.823,-4.704,3.881,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.213352,0.00180205,0.988118 beta-lactamase_625_I206S,beta-lactamase_625_206,TEM-1,beta-lactamase_625,P62593,0.988119,NO,206,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-2.429,-3.468,1.039,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.213352,0.00528934,0.988119 beta-lactamase_0_M184F,beta-lactamase_0_184,TEM-1,beta-lactamase_0,P62593,0.988122,NO,184,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.593,-2.94,1.347,,,H,A,0.55,-0.87,13.292,13.292,62.94,HHH,-1.41,0.0500837,0.00356019,0.988122 beta-lactamase_156_E56N,beta-lactamase_156_56,TEM-1,beta-lactamase_156,P62593,0.988128,NO,56,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.043,-2.542,0.499,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.111618,0.00238534,0.988128 beta-lactamase_2500_D252E,beta-lactamase_2500_252,TEM-1,beta-lactamase_2500,P62593,0.988131,NO,252,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.94,,,,0.766,,B,1.59,1.16,,,67.83,OAO,-2.0965,0.361275,0.00575769,0.988131 beta-lactamase_39_T264R,beta-lactamase_39_264,TEM-1,beta-lactamase_39,P62593,0.988138,NO,264,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.0495842,0.0119399,0.988138 beta-lactamase_156_R162L,beta-lactamase_156_162,TEM-1,beta-lactamase_156,P62593,0.988141,NO,162,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.016,-2.541,1.525,,0.124,S,B,1.2,-0.37,7.444,,64.69,ABH,-1.25,0.111618,0.000561334,0.988141 beta-lactamase_625_I171P,beta-lactamase_625_171,TEM-1,beta-lactamase_625,P62593,0.988141,NO,171,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-2.431,-4.052,1.621,,0.361,,B,0.48,0.53,3.869,,77.62,HHO,-1.55533,0.213352,0.00623355,0.988141 Pab1_D160K,Pab1_160,Pab1,Pab1,P04147,0.988141,NO,160,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.985,-3.274,2.289,,0.396,B,B,,1.12,,,,PAA,-1.30133,0.175299,0.000311977,0.988141 beta-lactamase_156_G85T,beta-lactamase_156_85,TEM-1,beta-lactamase_156,P62593,0.988142,NO,85,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.011,-3.637,2.626,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.111618,0.00252173,0.988142 beta-lactamase_2500_E166L,beta-lactamase_2500_166,TEM-1,beta-lactamase_2500,P62593,0.988145,NO,166,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.756,-2.872,1.116,,0.508,G,A,1.04,1.05,2.124,,73.08,OAH,-1.42233,0.361275,0.00512989,0.988145 beta-lactamase_0_A282F,beta-lactamase_0_282,TEM-1,beta-lactamase_0,P62593,0.988149,NO,282,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.0500837,0.0449821,0.988149 beta-lactamase_156_L137A,beta-lactamase_156_137,TEM-1,beta-lactamase_156,P62593,0.988157,NO,137,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.03,-3.142,2.112,,,H,A,0.55,-0.38,0.674,,42.31,HHP,-1.58933,0.111618,0.00278599,0.988157 beta-lactamase_2500_A148T,beta-lactamase_2500_148,TEM-1,beta-lactamase_2500,P62593,0.988157,NO,148,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.757,-2.508,0.751,,0.379,H,A,0.46,-0.55,2.117,,72.73,PHH,-1.40167,0.361275,0.00547053,0.988157 beta-lactamase_625_V31A,beta-lactamase_625_31,TEM-1,beta-lactamase_625,P62593,0.988157,NO,31,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.822,-2.265,0.443,,,H,A,0.44,-0.46,2.576,,73.78,BHB,-2.03767,0.213352,0.00478065,0.988157 beta-lactamase_156_T116K,beta-lactamase_156_116,TEM-1,beta-lactamase_156,P62593,0.988159,NO,116,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.28,-3.42,2.14,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.111618,0.00336175,0.988159 beta-lactamase_625_Q203N,beta-lactamase_625_203,TEM-1,beta-lactamase_625,P62593,0.98816,NO,203,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.168,-3.727,1.559,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.213352,0.00631514,0.98816 beta-lactamase_156_F70C,beta-lactamase_156_70,TEM-1,beta-lactamase_156,P62593,0.988162,NO,70,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.169,-4.871,3.702,,,H,A,0.58,-1.34,1.918,,63.99,PHB,-0.980667,0.111618,0.00193499,0.988162 beta-lactamase_156_G114L,beta-lactamase_156_114,TEM-1,beta-lactamase_156,P62593,0.988162,NO,114,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.094,-3.637,2.543,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.111618,0.00224919,0.988162 beta-lactamase_625_E62M,beta-lactamase_625_62,TEM-1,beta-lactamase_625,P62593,0.988173,NO,62,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.193,-4.77,3.577,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.213352,0.00264802,0.988173 beta-lactamase_39_Q204M,beta-lactamase_39_204,TEM-1,beta-lactamase_39,P62593,0.988176,NO,204,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-1.382,-4.445,3.063,,0.204,H,A,0.64,0.09,0.489,,66.08,PPH,-1.49067,0.0495842,0.00364106,0.988176 beta-lactamase_156_Y95L,beta-lactamase_156_95,TEM-1,beta-lactamase_156,P62593,0.988178,NO,95,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-1.715,-2.545,0.83,,0.122,,b,0.21,-0.37,2.341,,77.62,BHP,-2.16167,0.111618,0.00479449,0.988178 beta-lactamase_2500_R189S,beta-lactamase_2500_189,TEM-1,beta-lactamase_2500,P62593,0.988182,NO,189,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.844,-2.849,1.005,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.361275,0.0050699,0.988182 beta-lactamase_156_P224V,beta-lactamase_156_224,TEM-1,beta-lactamase_156,P62593,0.988184,NO,224,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.893,-3.599,2.706,,0.383,,B,0.52,-0.3,0.383,,74.48,HOH,-1.26433,0.111618,0.00189564,0.988184 beta-lactamase_156_S256L,beta-lactamase_156_256,TEM-1,beta-lactamase_156,P62593,0.988197,NO,256,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.111618,0.00710634,0.988197 beta-lactamase_39_R176Y,beta-lactamase_39_176,TEM-1,beta-lactamase_39,P62593,0.988199,NO,176,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-0.863,-4.162,3.299,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.0495842,0.00105554,0.988199 beta-lactamase_156_T116C,beta-lactamase_156_116,TEM-1,beta-lactamase_156,P62593,0.9882,NO,116,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.28,-4.831,3.551,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.111618,0.00336175,0.9882 beta-lactamase_156_H24W,beta-lactamase_156_24,TEM-1,beta-lactamase_156,P62593,0.988201,NO,24,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-2.481,-5.305,2.824,,,,,,,2.708,,93.01,OBO,-2.0035,0.111618,0.00238894,0.988201 beta-lactamase_156_A247H,beta-lactamase_156_247,TEM-1,beta-lactamase_156,P62593,0.988204,NO,247,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.111618,0.00611275,0.988204 beta-lactamase_39_N173C,beta-lactamase_39_173,TEM-1,beta-lactamase_39,P62593,0.988205,NO,173,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-2.663,-5.092,2.429,,1.044,T,l,0.61,1.25,1.426,,77.62,OPA,-1.46633,0.0495842,0.0033769,0.988205 beta-lactamase_39_I229T,beta-lactamase_39_229,TEM-1,beta-lactamase_39,P62593,0.988207,NO,229,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.267,-2.621,1.354,,0.083,E,B,0.48,-0.76,1.114,,50,HHH,-1.58767,0.0495842,0.00477249,0.988207 beta-lactamase_625_T264E,beta-lactamase_625_264,TEM-1,beta-lactamase_625,P62593,0.988212,NO,264,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.213352,0.0119399,0.988212 beta-lactamase_L160M,beta-lactamase_160,TEM-1,beta-lactamase,P62593,0.988212,NO,160,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.977,-3.902,2.925,5.32068,0.022,,B,1.75,-0.6,0.895,,44.41,BHA,-0.936,0.221079,0.00193775,0.988212 beta-lactamase_156_I245F,beta-lactamase_156_245,TEM-1,beta-lactamase_156,P62593,0.988213,NO,245,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.111618,0.00391032,0.988213 beta-lactamase_39_V117L,beta-lactamase_39_117,TEM-1,beta-lactamase_39,P62593,0.988221,NO,117,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.53,-1.606,0.076,,,H,A,0.44,-0.34,1.182,,65.03,PHB,-1.741,0.0495842,0.00467906,0.988221 beta-lactamase_G251A,beta-lactamase_251,TEM-1,beta-lactamase,P62593,0.988225,NO,251,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.907,-2.758,0.851,5.33865,0.506,T,l,0.73,0.17,10.663,,65.38,AOB,-2.06067,0.221079,0.00733416,0.988225 beta-lactamase_2500_R275V,beta-lactamase_2500_275,TEM-1,beta-lactamase_2500,P62593,0.988231,NO,275,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.361275,0.0141984,0.988231 beta-lactamase_156_Q204V,beta-lactamase_156_204,TEM-1,beta-lactamase_156,P62593,0.988232,NO,204,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-1.382,-3.595,2.213,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.111618,0.00364106,0.988232 beta-lactamase_2500_G90M,beta-lactamase_2500_90,TEM-1,beta-lactamase_2500,P62593,0.988234,NO,90,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-2.091,-4.839,2.748,,0.598,T,A,0.29,0.32,1.2,,77.62,HOB,-1.52633,0.361275,0.00490273,0.988234 beta-lactamase_625_R202N,beta-lactamase_625_202,TEM-1,beta-lactamase_625,P62593,0.988237,NO,202,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.292,-3.543,2.251,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.213352,0.00321899,0.988237 beta-lactamase_V8R,beta-lactamase_8,TEM-1,beta-lactamase,P62593,0.988245,NO,8,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-2.358,-2.351,-0.007,,,,,,,0.575,,77.62,BHH,-2.06267,0.221079,0.00226401,0.988245 beta-lactamase_156_A77Q,beta-lactamase_156_77,TEM-1,beta-lactamase_156,P62593,0.988253,NO,77,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.234,-4.052,2.818,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.111618,0.00282362,0.988253 beta-lactamase_625_H94I,beta-lactamase_625_94,TEM-1,beta-lactamase_625,P62593,0.988254,NO,94,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-2.5,-2.913,0.413,,0.776,,B,0.17,1.24,19.42,19.42,77.62,HBH,-1.872,0.213352,0.00389226,0.988254 beta-lactamase_2500_E272S,beta-lactamase_2500_272,TEM-1,beta-lactamase_2500,P62593,0.988255,NO,272,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.361275,0.00545371,0.988255 beta-lactamase_156_Q267F,beta-lactamase_156_267,TEM-1,beta-lactamase_156,P62593,0.98826,NO,267,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.111618,0.0102128,0.98826 beta-lactamase_2500_A148W,beta-lactamase_2500_148,TEM-1,beta-lactamase_2500,P62593,0.988261,NO,148,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.757,-5.497,3.74,,0.379,H,A,0.46,-0.55,2.117,,72.73,PHH,-1.40167,0.361275,0.00547053,0.988261 beta-lactamase_625_S266Q,beta-lactamase_625_266,TEM-1,beta-lactamase_625,P62593,0.988262,NO,266,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.213352,0.0140785,0.988262 beta-lactamase_2500_D271N,beta-lactamase_2500_271,TEM-1,beta-lactamase_2500,P62593,0.988263,NO,271,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.361275,0.00752082,0.988263 kka2_1:2_D157G,kka2_1:2_157,Kka2,kka2_1:2,P00552,0.988263,NO,157,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.993,-2.513,1.52,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.295029,0.0042313,0.988263 beta-lactamase_0_A34H,beta-lactamase_0_34,TEM-1,beta-lactamase_0,P62593,0.988265,NO,34,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.059,-4.883,2.824,,,H,A,0.46,-0.54,3.998,,73.78,AHA,-1.74967,0.0500837,0.00407913,0.988265 beta-lactamase_156_V101C,beta-lactamase_156_101,TEM-1,beta-lactamase_156,P62593,0.988265,NO,101,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.295,-4.837,3.542,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.111618,0.00374492,0.988265 beta-lactamase_156_I125C,beta-lactamase_156_125,TEM-1,beta-lactamase_156,P62593,0.988267,NO,125,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.441,-4.783,3.342,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.111618,0.00383964,0.988267 beta-lactamase_39_R239V,beta-lactamase_39_239,TEM-1,beta-lactamase_39,P62593,0.988267,NO,239,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.0495842,0.00213852,0.988267 beta-lactamase_156_Y103D,beta-lactamase_156_103,TEM-1,beta-lactamase_156,P62593,0.988268,NO,103,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-1.33,-3.794,2.464,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.111618,0.00443048,0.988268 beta-lactamase_39_L192H,beta-lactamase_39_192,TEM-1,beta-lactamase_39,P62593,0.988268,NO,192,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.254,-4.926,3.672,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.0495842,0.00558728,0.988268 beta-lactamase_625_E145D,beta-lactamase_625_145,TEM-1,beta-lactamase_625,P62593,0.988268,NO,145,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.357,-3.52,1.163,,0.545,H,A,1.04,0.79,2.64,,77.62,BAH,-2.069,0.213352,0.00553285,0.988268 beta-lactamase_39_G141Y,beta-lactamase_39_141,TEM-1,beta-lactamase_39,P62593,0.988272,NO,141,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.828,-4.424,3.596,,0.575,T,l,0.29,-0.28,0.722,,64.69,HOO,-1.08933,0.0495842,0.0012419,0.988272 beta-lactamase_156_S233A,beta-lactamase_156_233,TEM-1,beta-lactamase_156,P62593,0.988273,NO,233,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.886,-2.424,0.538,,0.016,E,B,0.27,-1.01,4.111,,77.62,BPO,-1.17267,0.111618,0.00311415,0.988273 beta-lactamase_625_T138F,beta-lactamase_625_138,TEM-1,beta-lactamase_625,P62593,0.988276,NO,138,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.506,-4.444,1.938,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.213352,0.00487868,0.988276 Pab1_K180L,Pab1_180,Pab1,Pab1,P04147,0.988278,NO,180,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.945,-3.424,1.479,,,,,,,,,,HBA,-1.575,0.175299,0.00295933,0.988278 Pab1_L142M,Pab1_142,Pab1,Pab1,P04147,0.98828,NO,142,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.039,-3.622,2.583,,0.007,H,A,0.84,-0.65,,,,HHH,-1.487,0.175299,0.000335477,0.98828 beta-lactamase_625_H94G,beta-lactamase_625_94,TEM-1,beta-lactamase_625,P62593,0.988281,NO,94,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-2.5,-3.593,1.093,,0.776,,B,0.17,1.24,19.42,19.42,77.62,HBH,-1.872,0.213352,0.00389226,0.988281 Pab1_A179S,Pab1_179,Pab1,Pab1,P04147,0.988281,NO,179,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.013,-2.753,1.74,,0.078,H,A,0.61,0.5,,,,HHB,-1.51233,0.175299,0.000291703,0.988281 beta-lactamase_2500_E26S,beta-lactamase_2500_26,TEM-1,beta-lactamase_2500,P62593,0.988285,NO,26,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.454,-3.34,0.886,,0.54,H,A,1.04,0.98,0.49,,93.01,OAP,-1.96167,0.361275,0.00297948,0.988285 beta-lactamase_625_L38A,beta-lactamase_625_38,TEM-1,beta-lactamase_625,P62593,0.988291,NO,38,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.343,-3.151,1.808,,0.088,H,A,0.55,0.2,1.986,,64.34,PHO,-1.78033,0.213352,0.00373244,0.988291 beta-lactamase_2500_M67G,beta-lactamase_2500_67,TEM-1,beta-lactamase_2500,P62593,0.988293,NO,67,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-2.231,-2.754,0.523,,0.006,G,P,0.55,-0.81,2.653,,65.03,HHP,-1.502,0.361275,0.00409753,0.988293 PSD95pdz3_A370Q,PSD95pdz3_370,PSD95pdz3,PSD95pdz3,P31016,0.988299,NO,370,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.307,-3.581,2.274,5.22304,,,,,17.284,,,,PHP,-1.57967,0.0758425,0.000429106,0.988299 beta-lactamase_G194E,beta-lactamase_194,TEM-1,beta-lactamase,P62593,0.9883,NO,194,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.396,-2.361,0.965,5.46622,0.276,S,b,0.77,0.36,3.593,,67.83,POA,-1.832,0.221079,0.00392163,0.9883 beta-lactamase_V157R,beta-lactamase_157,TEM-1,beta-lactamase,P62593,0.9883,NO,157,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.751,-3.07,1.319,5.51733,0.308,S,a,0.96,-0.75,1.847,,69.58,BHP,-2.00767,0.221079,0.00506849,0.9883 beta-lactamase_2500_Q276T,beta-lactamase_2500_276,TEM-1,beta-lactamase_2500,P62593,0.988301,NO,276,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.361275,0.0191712,0.988301 beta-lactamase_625_G253W,beta-lactamase_625_253,TEM-1,beta-lactamase_625,P62593,0.988301,NO,253,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.213352,0.00786358,0.988301 beta-lactamase_625_L219M,beta-lactamase_625_219,TEM-1,beta-lactamase_625,P62593,0.988302,NO,219,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.313,-3.006,1.693,,,I,A,0.55,-0.51,5.627,,74.48,HHB,-1.21533,0.213352,0.00664345,0.988302 beta-lactamase_156_K213L,beta-lactamase_156_213,TEM-1,beta-lactamase_156,P62593,0.988308,NO,213,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.81,-3.558,1.748,,0.67,,A,2.34,0.29,3.924,,67.83,ABH,-1.57767,0.111618,0.00610411,0.988308 beta-lactamase_R238Q,beta-lactamase_238,TEM-1,beta-lactamase,P62593,0.988309,NO,238,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.002,-3.002,1,5.87663,0.564,T,L,0.45,1.09,4.195,,72.73,ABO,-1.62633,0.221079,0.00743256,0.988309 beta-lactamase_39_P172S,beta-lactamase_39_172,TEM-1,beta-lactamase_39,P62593,0.988312,NO,172,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.998,-2.394,1.396,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.0495842,0.00312594,0.988312 beta-lactamase_156_F58E,beta-lactamase_156_58,TEM-1,beta-lactamase_156,P62593,0.988316,NO,58,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-2.914,-3.579,0.665,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.111618,0.00523369,0.988316 beta-lactamase_2500_N152A,beta-lactamase_2500_152,TEM-1,beta-lactamase_2500,P62593,0.988318,NO,152,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-2.757,-2.374,-0.383,,0.863,H,A,0.61,0.92,2.061,,77.62,BPH,-2.97,0.361275,0.00471429,0.988318 PSD95pdz3_G322V,PSD95pdz3_322,PSD95pdz3,PSD95pdz3,P31016,0.988321,NO,322,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.008,-3.435,2.427,5.24791,,,,,16.3275,,,,POH,-1.24867,0.0758425,0.00105821,0.988321 beta-lactamase_39_E108Q,beta-lactamase_39_108,TEM-1,beta-lactamase_39,P62593,0.988322,NO,108,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.46,-2.893,1.433,,0.572,G,A,1.04,1.87,20.151,20.151,72.73,PAB,-1.437,0.0495842,0.00413372,0.988322 beta-lactamase_625_V42M,beta-lactamase_625_42,TEM-1,beta-lactamase_625,P62593,0.988328,NO,42,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.564,-2.813,1.249,,0.017,E,B,0.44,-0.51,2.576,,63.99,BHO,-1.042,0.213352,0.00404515,0.988328 beta-lactamase_156_T27G,beta-lactamase_156_27,TEM-1,beta-lactamase_156,P62593,0.988335,NO,27,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.905,-3.36,1.455,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.111618,0.00306559,0.988335 beta-lactamase_39_K213Y,beta-lactamase_39_213,TEM-1,beta-lactamase_39,P62593,0.988338,NO,213,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.81,-4.305,2.495,,0.67,,A,2.34,0.29,2.648,,67.83,ABH,-1.57767,0.0495842,0.00610411,0.988338 beta-lactamase_156_K53W,beta-lactamase_156_53,TEM-1,beta-lactamase_156,P62593,0.988339,NO,53,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-2.313,-2.612,0.299,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.111618,0.00383383,0.988339 beta-lactamase_39_E102G,beta-lactamase_39_102,TEM-1,beta-lactamase_39,P62593,0.98834,NO,102,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.118,-2.728,0.61,,0.722,S,B,1.04,1.82,3.87,,73.08,HAH,-1.581,0.0495842,0.00486633,0.98834 beta-lactamase_156_N152P,beta-lactamase_156_152,TEM-1,beta-lactamase_156,P62593,0.988343,NO,152,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-2.757,-3.97,1.213,,0.863,H,A,0.61,0.92,4.038,,77.62,BPH,-2.97,0.111618,0.00471429,0.988343 kka2_1:2_E169D,kka2_1:2_169,Kka2,kka2_1:2,P00552,0.988344,NO,169,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.996,-1.998,0.002,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.295029,0.00730086,0.988344 beta-lactamase_156_G253D,beta-lactamase_156_253,TEM-1,beta-lactamase_156,P62593,0.988345,NO,253,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.111618,0.00786358,0.988345 beta-lactamase_625_L192A,beta-lactamase_625_192,TEM-1,beta-lactamase_625,P62593,0.988346,NO,192,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.254,-2.317,1.063,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.213352,0.00558728,0.988346 beta-lactamase_625_G90D,beta-lactamase_625_90,TEM-1,beta-lactamase_625,P62593,0.988351,NO,90,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-2.091,-2.02,-0.071,,0.598,T,A,0.29,0.32,0.319,,77.62,HOB,-1.52633,0.213352,0.00490273,0.988351 beta-lactamase_39_E119G,beta-lactamase_39_119,TEM-1,beta-lactamase_39,P62593,0.988352,NO,119,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.412,-2.405,0.993,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.0495842,0.00386966,0.988352 beta-lactamase_39_Q267M,beta-lactamase_39_267,TEM-1,beta-lactamase_39,P62593,0.988357,NO,267,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.0495842,0.0102128,0.988357 beta-lactamase_156_T269L,beta-lactamase_156_269,TEM-1,beta-lactamase_156,P62593,0.988358,NO,269,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.111618,0.00950944,0.988358 beta-lactamase_625_G216N,beta-lactamase_625_216,TEM-1,beta-lactamase_625,P62593,0.988362,NO,216,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.477,-2.771,1.294,,0.437,I,A,0.29,-0.58,1.718,,74.48,HOO,-1.68067,0.213352,0.00639568,0.988362 beta-lactamase_2500_Q86I,beta-lactamase_2500_86,TEM-1,beta-lactamase_2500,P62593,0.988369,NO,86,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.4,-3.877,1.477,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.361275,0.00450027,0.988369 beta-lactamase_39_V214Y,beta-lactamase_39_214,TEM-1,beta-lactamase_39,P62593,0.988371,NO,214,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.299,-4.125,2.826,,0.375,S,A,0.44,-0.44,18.838,18.838,74.48,BHH,-1.53733,0.0495842,0.00628442,0.988371 beta-lactamase_625_A182E,beta-lactamase_625_182,TEM-1,beta-lactamase_625,P62593,0.988374,NO,182,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.777,-2.345,0.568,,0.136,H,A,0.46,-0.66,16.784,16.784,93.01,OHH,-1.27367,0.213352,0.00559099,0.988374 beta-lactamase_625_M153S,beta-lactamase_625_153,TEM-1,beta-lactamase_625,P62593,0.988378,NO,153,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-3.193,-2.433,-0.76,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.213352,0.00509109,0.988378 PSD95pdz3_A390K,PSD95pdz3_390,PSD95pdz3,PSD95pdz3,P31016,0.98838,NO,390,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.307,-3.139,1.832,5.03823,,,,,12.46,,,,HHP,-1.54467,0.0758425,0.00104603,0.98838 PSD95pdz3_R313M,PSD95pdz3_313,PSD95pdz3,PSD95pdz3,P31016,0.988381,NO,313,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.582,-4.162,2.58,6.63563,,,,,18.3955,,,,BBH,-1.59733,0.0758425,0.000840067,0.988381 beta-lactamase_156_E46S,beta-lactamase_156_46,TEM-1,beta-lactamase_156,P62593,0.988384,NO,46,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.94,-3.545,1.605,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.111618,0.00427568,0.988384 beta-lactamase_39_H94A,beta-lactamase_39_94,TEM-1,beta-lactamase_39,P62593,0.988385,NO,94,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-2.5,-2.468,-0.032,,0.776,,B,0.17,1.24,11.583,11.583,77.62,HBH,-1.872,0.0495842,0.00389226,0.988385 beta-lactamase_39_T198H,beta-lactamase_39_198,TEM-1,beta-lactamase_39,P62593,0.988387,NO,198,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.168,-3.211,1.043,,0.489,,B,0.22,-0.13,3.614,,73.78,HPH,-1.98767,0.0495842,0.004311,0.988387 beta-lactamase_625_K286C,beta-lactamase_625_286,TEM-1,beta-lactamase_625,P62593,0.988392,NO,286,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.213352,,0.988392 PSD95pdz3_S371W,PSD95pdz3_371,PSD95pdz3,PSD95pdz3,P31016,0.988397,NO,371,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.86,-4.958,3.098,5.19744,,,,,17.1117,3.854,,87.71,HPB,-1.598,0.0758425,0.000847873,0.988397 beta-lactamase_39_L218C,beta-lactamase_39_218,TEM-1,beta-lactamase_39,P62593,0.988401,NO,218,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.391,-4.928,3.537,,,I,b,0.55,-0.53,2.038,,74.48,OHH,-1.58867,0.0495842,0.00618274,0.988401 beta-lactamase_0_W163G,beta-lactamase_0_163,TEM-1,beta-lactamase_0,P62593,0.98841,NO,163,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-1.843,-2.648,0.805,,0.467,,B,0.47,-0.5,13.843,13.843,63.99,BHA,-1.269,0.0500837,0.00418955,0.98841 beta-lactamase_625_Q267G,beta-lactamase_625_267,TEM-1,beta-lactamase_625,P62593,0.988415,NO,267,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.213352,0.0102128,0.988415 beta-lactamase_S57H,beta-lactamase_57,TEM-1,beta-lactamase,P62593,0.988418,NO,57,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.918,-3.329,1.411,5.64201,0.352,E,B,0.25,-0.18,1.971,,72.73,APH,-2.29167,0.221079,0.00492804,0.988418 beta-lactamase_39_Q203V,beta-lactamase_39_203,TEM-1,beta-lactamase_39,P62593,0.988419,NO,203,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.168,-3.605,1.437,,0.47,H,A,0.64,-0.38,1.453,,65.38,BPP,-1.614,0.0495842,0.00631514,0.988419 kka2_1:2_K138T,kka2_1:2_138,Kka2,kka2_1:2,P00552,0.98842,NO,138,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-2.5,-2.841,0.341,,0.594,H,A,2.34,0.98,21.038,21.038,71.59,HBB,-2.48833,0.295029,0.00628542,0.98842 beta-lactamase_156_D48A,beta-lactamase_156_48,TEM-1,beta-lactamase_156,P62593,0.988429,NO,48,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.101,-2.565,1.464,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.111618,0.0027273,0.988429 beta-lactamase_39_Q97A,beta-lactamase_39_97,TEM-1,beta-lactamase_39,P62593,0.988429,NO,97,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.072,-2.26,0.188,,0.823,G,A,0.64,2.42,4.457,,77.62,PPP,-2.43833,0.0495842,0.0045116,0.988429 beta-lactamase_0_D113N,beta-lactamase_0_113,TEM-1,beta-lactamase_0,P62593,0.988432,NO,113,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.829,-3.682,1.853,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.0500837,0.00474112,0.988432 beta-lactamase_156_D99T,beta-lactamase_156_99,TEM-1,beta-lactamase_156,P62593,0.988434,NO,99,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.191,-3.531,2.34,,0.402,G,A,0.75,0.36,3.529,,64.69,PAH,-1.794,0.111618,0.00305446,0.988434 beta-lactamase_39_Y262L,beta-lactamase_39_262,TEM-1,beta-lactamase_39,P62593,0.988435,NO,262,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.0495842,0.00853516,0.988435 kka2_1:4_A87F,kka2_1:4_87,Kka2,kka2_1:4,P00552,0.988436,NO,87,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.917,-4.449,2.532,,1.039,S,L,0.46,1.57,22.675,22.675,65.53,AHO,-1.822,0.168804,0.00791281,0.988436 beta-lactamase_Q203A,beta-lactamase_203,TEM-1,beta-lactamase,P62593,0.98844,NO,203,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.168,-2.117,-0.051,5.65296,0.47,H,A,0.12,-0.38,1.66,,65.38,BPP,-1.614,0.221079,0.00631514,0.98844 beta-lactamase_625_L197M,beta-lactamase_625_197,TEM-1,beta-lactamase_625,P62593,0.988441,NO,197,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.853,-3.888,3.035,,0.007,S,B,0.55,0.33,1.756,,60.14,HHP,-1.833,0.213352,0.00144602,0.988441 beta-lactamase_156_L219S,beta-lactamase_156_219,TEM-1,beta-lactamase_156,P62593,0.988444,NO,219,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.313,-3.686,2.373,,,I,A,0.55,-0.51,2.321,,74.48,HHB,-1.21533,0.111618,0.00664345,0.988444 Pab1_E175S,Pab1_175,Pab1,Pab1,P04147,0.988446,NO,175,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.055,-2.062,0.007,,,,,,,,,,AAA,-1.82667,0.175299,0.00203137,0.988446 beta-lactamase_625_A170I,beta-lactamase_625_170,TEM-1,beta-lactamase_625,P62593,0.988447,NO,170,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.237,-3.643,2.406,,0.126,,L,0.46,-0.35,3.626,,64.69,AHH,-1.63267,0.213352,0.00431903,0.988447 beta-lactamase_156_E119K,beta-lactamase_156_119,TEM-1,beta-lactamase_156,P62593,0.98845,NO,119,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.412,-3.343,1.931,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.111618,0.00386966,0.98845 beta-lactamase_625_Q97K,beta-lactamase_625_97,TEM-1,beta-lactamase_625,P62593,0.988454,NO,97,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.072,-2.314,0.242,,0.823,G,A,0.64,2.42,16.954,16.954,77.62,PPP,-2.43833,0.213352,0.0045116,0.988454 beta-lactamase_39_P255H,beta-lactamase_39_255,TEM-1,beta-lactamase_39,P62593,0.988459,NO,255,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.0495842,0.00499612,0.988459 beta-lactamase_R118D,beta-lactamase_118,TEM-1,beta-lactamase,P62593,0.98846,NO,118,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.413,-2.866,0.453,5.8227,0.457,H,A,0.68,1.39,2.144,,77.62,HBA,-1.785,0.221079,0.00538794,0.98846 beta-lactamase_2500_K286A,beta-lactamase_2500_286,TEM-1,beta-lactamase_2500,P62593,0.988469,NO,286,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.361275,,0.988469 Pab1_S147G,Pab1_147,Pab1,Pab1,P04147,0.98847,NO,147,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.267,-2.871,1.604,,0.336,H,A,,0.56,,,,HPH,-1.43033,0.175299,0.000610856,0.98847 beta-lactamase_39_L38P,beta-lactamase_39_38,TEM-1,beta-lactamase_39,P62593,0.988475,NO,38,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.343,-2.934,1.591,,0.088,H,A,0.55,0.2,17.089,17.089,64.34,PHO,-1.78033,0.0495842,0.00373244,0.988475 beta-lactamase_625_E108Y,beta-lactamase_625_108,TEM-1,beta-lactamase_625,P62593,0.988477,NO,108,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.46,-4.347,2.887,,0.572,G,A,1.04,1.87,20.151,20.151,72.73,PAB,-1.437,0.213352,0.00413372,0.988477 beta-lactamase_156_A278M,beta-lactamase_156_278,TEM-1,beta-lactamase_156,P62593,0.988484,NO,278,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.111618,0.0310297,0.988484 beta-lactamase_39_S266V,beta-lactamase_39_266,TEM-1,beta-lactamase_39,P62593,0.988485,NO,266,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.0495842,0.0140785,0.988485 beta-lactamase_156_D252V,beta-lactamase_156_252,TEM-1,beta-lactamase_156,P62593,0.988487,NO,252,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.111618,0.00575769,0.988487 Pab1_G177E,Pab1_177,Pab1,Pab1,P04147,0.988493,NO,177,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-2.24,-1.798,-0.442,,,,,,,,,,AOH,-1.94067,0.175299,0.00170727,0.988493 beta-lactamase_M180I,beta-lactamase_180,TEM-1,beta-lactamase,P62593,0.988494,NO,180,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-2.795,-3.664,0.869,4.96809,0.242,,B,1.07,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.221079,0.00552048,0.988494 beta-lactamase_S104S,beta-lactamase_104,TEM-1,beta-lactamase,P62593,0.988494,NO,104,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.015,-1.015,,4.92365,0.04,,b,0.82,0.57,4.02,,63.29,HPO,-1.05267,0.221079,0.00218083,0.988494 gb1_K230W,gb1_230,gb1,gb1,P06654,0.988495,NO,230,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.701,-4.42,2.719,,,,,,,0.166,,11.83,HBH,-1.52867,0.177985,0.00331703,0.988495 gb1_T251G,gb1_251,gb1,gb1,P06654,0.988495,NO,251,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.794,-3.275,1.481,,,,,,,3.514,3.514,37.28,HPH,-1.56067,0.177985,0.00232932,0.988495 beta-lactamase_625_N98D,beta-lactamase_625_98,TEM-1,beta-lactamase_625,P62593,0.988497,NO,98,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-2.973,-2.35,-0.623,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.213352,0.00505389,0.988497 beta-lactamase_156_T139A,beta-lactamase_156_139,TEM-1,beta-lactamase_156,P62593,0.988499,NO,139,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.901,-2.031,0.13,,0.216,H,A,0.22,0.39,16.34,16.34,77.62,PPH,-2.04667,0.111618,0.00441837,0.988499 beta-lactamase_39_S266C,beta-lactamase_39_266,TEM-1,beta-lactamase_39,P62593,0.988503,NO,266,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.0495842,0.0140785,0.988503 beta-lactamase_156_Q276W,beta-lactamase_156_276,TEM-1,beta-lactamase_156,P62593,0.988506,NO,276,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.111618,0.0191712,0.988506 E1_Ubiquitin_K48W,E1_Ubiquitin_48,Uba1,E1_Ubiquitin,P0CG63,0.988506,NO,48,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.219,-5.193,3.974,,0.132,E,B,,-0.28,,,,OBO,-1.109,0.18783,0.00100363,0.988506 E1_Ubiquitin_L71F,E1_Ubiquitin_71,Uba1,E1_Ubiquitin,P0CG63,0.988506,NO,71,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.039,-3.434,2.395,,0.591,E,B,,-0.69,,,,BHB,-1.19433,0.18783,0.00148349,0.988506 beta-lactamase_156_E56T,beta-lactamase_156_56,TEM-1,beta-lactamase_156,P62593,0.988523,NO,56,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.043,-2.013,-0.03,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.111618,0.00238534,0.988523 beta-lactamase_625_Y95I,beta-lactamase_625_95,TEM-1,beta-lactamase_625,P62593,0.988526,NO,95,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-1.715,-1.963,0.248,,0.122,,b,0.21,-0.37,3.355,,77.62,BHP,-2.16167,0.213352,0.00479449,0.988526 beta-lactamase_39_L73E,beta-lactamase_39_73,TEM-1,beta-lactamase_39,P62593,0.988528,NO,73,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.507,-3.924,2.417,,,H,A,0.55,-0.64,2.09,,67.83,HHH,-1.487,0.0495842,0.00488983,0.988528 beta-lactamase_156_M115C,beta-lactamase_156_115,TEM-1,beta-lactamase_156,P62593,0.98853,NO,115,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.389,-4.767,3.378,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.111618,0.0034337,0.98853 beta-lactamase_2500_A222V,beta-lactamase_2500_222,TEM-1,beta-lactamase_2500,P62593,0.98853,NO,222,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.103,-1.973,-0.13,,0.233,H,A,0.46,-0.25,0.379,,77.62,PHH,-1.63733,0.361275,0.00466094,0.98853 beta-lactamase_625_P25Y,beta-lactamase_625_25,TEM-1,beta-lactamase_625,P62593,0.98853,NO,25,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.526,-4.327,2.801,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.213352,0.00347571,0.98853 beta-lactamase_625_E272N,beta-lactamase_625_272,TEM-1,beta-lactamase_625,P62593,0.988536,NO,272,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.127,-2.497,1.37,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.213352,0.00545371,0.988536 beta-lactamase_156_C121L,beta-lactamase_156_121,TEM-1,beta-lactamase_156,P62593,0.988551,NO,121,C,L,CL,Special,Hydrophobic,5.07,9.7088,4.6388,198,121,131,10,108.5,166.7,58.2,-0.953,-3.182,2.229,,,H,A,0.46,-0.81,1.136,,63.29,HOP,-1.46767,0.111618,0.000744322,0.988551 beta-lactamase_625_Q203D,beta-lactamase_625_203,TEM-1,beta-lactamase_625,P62593,0.988558,NO,203,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.168,-2.512,0.344,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.213352,0.00631514,0.988558 beta-lactamase_625_R162T,beta-lactamase_625_162,TEM-1,beta-lactamase_625,P62593,0.988566,NO,162,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.016,-3.471,2.455,,0.124,S,B,1.2,-0.37,1.445,,64.69,ABH,-1.25,0.213352,0.000561334,0.988566 beta-lactamase_625_P217N,beta-lactamase_625_217,TEM-1,beta-lactamase_625,P62593,0.988573,NO,217,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-2.062,-2.997,0.935,,0.496,I,A,0.52,-0.33,1.087,,74.48,OOH,-1.64333,0.213352,0.00463211,0.988573 beta-lactamase_0_P105C,beta-lactamase_0_105,TEM-1,beta-lactamase_0,P62593,0.988581,NO,105,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.813,-5.05,4.237,,0.226,T,A,0.52,0.8,3.48,,63.29,POH,-1.01533,0.0500837,0.0011981,0.988581 beta-lactamase_156_E46K,beta-lactamase_156_46,TEM-1,beta-lactamase_156,P62593,0.988581,NO,46,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.94,-3.66,1.72,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.111618,0.00427568,0.988581 beta-lactamase_625_G85L,beta-lactamase_625_85,TEM-1,beta-lactamase_625,P62593,0.988581,NO,85,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.011,-3.755,2.744,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.213352,0.00252173,0.988581 beta-lactamase_625_K254A,beta-lactamase_625_254,TEM-1,beta-lactamase_625,P62593,0.988586,NO,254,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.213352,0.00369,0.988586 beta-lactamase_156_A124N,beta-lactamase_156_124,TEM-1,beta-lactamase_156,P62593,0.988619,NO,124,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.181,-3.812,2.631,,,H,A,0.46,-0.9,2.027,,64.34,HHH,-1.152,0.111618,0.00481399,0.988619 Pab1_L142C,Pab1_142,Pab1,Pab1,P04147,0.98862,NO,142,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.039,-4.454,3.415,,0.007,H,A,0.84,-0.65,,,,HHH,-1.487,0.175299,0.000335477,0.98862 beta-lactamase_0_G249H,beta-lactamase_0_249,TEM-1,beta-lactamase_0,P62593,0.988632,NO,249,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.0500837,0.00220169,0.988632 kka2_1:8_L19M,kka2_1:8_19,Kka2,kka2_1:8,P00552,0.988634,NO,19,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.254,-4.18,2.926,,0.08,T,A,1.59,-0.26,2.044,,65.53,BHH,-2.221,0.100394,0.00620703,0.988634 kka2_1:8_L19M,kka2_1:8_19,Kka2,kka2_1:8,P00552,0.988634,NO,19,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.254,-4.18,2.926,,0.08,T,A,1.59,-0.26,2.044,,65.53,BHH,-2.221,0.100394,0.00620703,0.988634 beta-lactamase_625_V31L,beta-lactamase_625_31,TEM-1,beta-lactamase_625,P62593,0.988639,NO,31,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.822,-2.16,0.338,,,H,A,0.44,-0.46,2.576,,73.78,BHB,-2.03767,0.213352,0.00478065,0.988639 beta-lactamase_S122R,beta-lactamase_122,TEM-1,beta-lactamase,P62593,0.988639,NO,122,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.406,-3.131,0.725,4.87767,0.352,H,A,0.73,-0.54,1.581,,77.62,OPH,-1.39767,0.221079,0.00497825,0.988639 beta-lactamase_156_R257L,beta-lactamase_156_257,TEM-1,beta-lactamase_156,P62593,0.988641,NO,257,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.111618,0.00756629,0.988641 beta-lactamase_0_L74T,beta-lactamase_0_74,TEM-1,beta-lactamase_0,P62593,0.98865,NO,74,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.296,-3.432,2.136,,,H,A,0.55,-0.91,1.46,,50,HHO,-1.34933,0.0500837,0.00493255,0.98865 WW_domain_Y188Y,WW_domain_188,Yap65,WW_domain,P46937,0.988652,NO,188,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-1.326,-1.326,0,5.89734,,,,,,,,,BHH,-1.45333,0.153962,0.00265487,0.988652 beta-lactamase_39_R189L,beta-lactamase_39_189,TEM-1,beta-lactamase_39,P62593,0.988654,NO,189,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.844,-3.611,1.767,,0.278,H,A,1.2,1.01,12.11,12.11,72.73,HBB,-1.668,0.0495842,0.0050699,0.988654 beta-lactamase_625_H287Y,beta-lactamase_625_287,TEM-1,beta-lactamase_625,P62593,0.98866,NO,287,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,,,,,,,,,,,,,BBH,-1.111,0.213352,,0.98866 kka2_1:2_A71E,kka2_1:2_71,Kka2,kka2_1:2,P00552,0.988661,NO,71,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.824,-2.798,0.974,,0.553,H,A,0.46,0.08,9.788,,64.39,HHP,-1.74033,0.295029,0.00727707,0.988661 beta-lactamase_156_R257M,beta-lactamase_156_257,TEM-1,beta-lactamase_156,P62593,0.988665,NO,257,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.111618,0.00756629,0.988665 beta-lactamase_625_D207A,beta-lactamase_625_207,TEM-1,beta-lactamase_625,P62593,0.988666,NO,207,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.064,-2.585,0.521,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.213352,0.00592942,0.988666 beta-lactamase_A84S,beta-lactamase_84,TEM-1,beta-lactamase,P62593,0.988667,NO,84,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.651,-2.609,0.958,5.28927,0.65,T,A,0.52,0.96,1.863,,68.18,AHO,-1.24267,0.221079,0.00503822,0.988667 gb1_L233A,gb1_233,gb1,gb1,P06654,0.988668,NO,233,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-2.678,-2.853,0.175,,,,,,,0.822,,45.54,HHP,-2.30267,0.177985,0.00266958,0.988668 beta-lactamase_156_L199A,beta-lactamase_156_199,TEM-1,beta-lactamase_156,P62593,0.988669,NO,199,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-2.942,-2.055,-0.887,,0.832,H,A,0.55,0.42,1.552,,77.62,PHH,-2.32933,0.111618,0.0048649,0.988669 beta-lactamase_625_G90M,beta-lactamase_625_90,TEM-1,beta-lactamase_625,P62593,0.988669,NO,90,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-2.091,-4.839,2.748,,0.598,T,A,0.29,0.32,0.319,,77.62,HOB,-1.52633,0.213352,0.00490273,0.988669 beta-lactamase_625_C121M,beta-lactamase_625_121,TEM-1,beta-lactamase_625,P62593,0.988677,NO,121,C,M,CM,Special,Hydrophobic,5.07,5.74,0.67,196,121,149,28,108.5,162.9,54.4,-0.953,-4.506,3.553,,,H,A,0.46,-0.81,1.143,,63.29,HOP,-1.46767,0.213352,0.000744322,0.988677 beta-lactamase_2500_E169Q,beta-lactamase_2500_169,TEM-1,beta-lactamase_2500,P62593,0.988678,NO,169,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.23,-2.523,1.293,,0.337,,A,1.04,1,1.806,,73.08,PAH,-1.16533,0.361275,0.00400994,0.988678 Pab1_I183M,Pab1_183,Pab1,Pab1,P04147,0.988678,NO,183,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.302,-3.9,2.598,,0.308,T,B,1,1.08,1.29,,75.56,HHA,-1.27167,0.175299,0.000574345,0.988678 kka2_1:8_L60Q,kka2_1:8_60,Kka2,kka2_1:8,P00552,0.988685,NO,60,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.997,-4.233,3.236,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.100394,0.00262176,0.988685 kka2_1:8_L60Q,kka2_1:8_60,Kka2,kka2_1:8,P00552,0.988685,NO,60,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.997,-4.233,3.236,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.100394,0.00262176,0.988685 beta-lactamase_625_H151F,beta-lactamase_625_151,TEM-1,beta-lactamase_625,P62593,0.988687,NO,151,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-2.96,-4.308,1.348,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.213352,0.00216946,0.988687 beta-lactamase_156_H94P,beta-lactamase_156_94,TEM-1,beta-lactamase_156,P62593,0.988693,NO,94,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-2.5,-2.499,-0.001,,0.776,,B,0.17,1.24,11.583,11.583,77.62,HBH,-1.872,0.111618,0.00389226,0.988693 kka2_1:4_R44T,kka2_1:4_44,Kka2,kka2_1:4,P00552,0.988695,NO,44,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.062,-3.662,1.6,,0.487,S,B,1.2,-0.35,5.71,,71.59,OBO,-1.80767,0.168804,0.00745043,0.988695 beta-lactamase_2500_D33E,beta-lactamase_2500_33,TEM-1,beta-lactamase_2500,P62593,0.9887,NO,33,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.321,-2.159,-0.162,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.361275,0.00435556,0.9887 beta-lactamase_156_I140Y,beta-lactamase_156_140,TEM-1,beta-lactamase_156,P62593,0.988704,NO,140,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.733,-3.996,2.263,,0.128,H,A,0.48,0.41,1.16,,73.08,PHO,-1.48733,0.111618,0.00597777,0.988704 beta-lactamase_39_W163C,beta-lactamase_39_163,TEM-1,beta-lactamase_39,P62593,0.988706,NO,163,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-1.843,-5.117,3.274,,0.467,,B,0.47,-0.5,15.095,15.095,63.99,BHA,-1.269,0.0495842,0.00418955,0.988706 beta-lactamase_625_G85R,beta-lactamase_625_85,TEM-1,beta-lactamase_625,P62593,0.988708,NO,85,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.011,-2.784,1.773,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.213352,0.00252173,0.988708 beta-lactamase_2500_T193G,beta-lactamase_2500_193,TEM-1,beta-lactamase_2500,P62593,0.988712,NO,193,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.914,-3.548,1.634,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.361275,0.00482669,0.988712 beta-lactamase_156_L111W,beta-lactamase_156_111,TEM-1,beta-lactamase_156,P62593,0.988715,NO,111,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.76,-5.305,3.545,,0.328,T,A,0.55,0.93,2.26,,64.34,BHP,-1.884,0.111618,0.00480671,0.988715 beta-lactamase_39_G216D,beta-lactamase_39_216,TEM-1,beta-lactamase_39,P62593,0.988718,NO,216,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.477,-1.722,0.245,,0.437,I,A,0.29,-0.58,0.834,,74.48,HOO,-1.68067,0.0495842,0.00639568,0.988718 beta-lactamase_0_N274A,beta-lactamase_0_274,TEM-1,beta-lactamase_0,P62593,0.988723,NO,274,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.0500837,0.0110418,0.988723 PSD95pdz3_G383L,PSD95pdz3_383,PSD95pdz3,PSD95pdz3,P31016,0.988728,NO,383,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.008,-3.49,2.482,5.17213,,,,,20.5325,,,,HOP,-1.338,0.0758425,0.000233044,0.988728 beta-lactamase_2500_H94R,beta-lactamase_2500_94,TEM-1,beta-lactamase_2500,P62593,0.988739,NO,94,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-2.5,-2.531,0.031,,0.776,,B,0.17,1.24,1.176,,77.62,HBH,-1.872,0.361275,0.00389226,0.988739 beta-lactamase_156_G114Y,beta-lactamase_156_114,TEM-1,beta-lactamase_156,P62593,0.98874,NO,114,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.094,-4.391,3.297,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.111618,0.00224919,0.98874 beta-lactamase_156_Q88A,beta-lactamase_156_88,TEM-1,beta-lactamase_156,P62593,0.988748,NO,88,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.086,-2.75,0.664,,0.807,,B,0.64,2.03,0.911,,77.62,APH,-1.53433,0.111618,0.00504167,0.988748 beta-lactamase_39_P172G,beta-lactamase_39_172,TEM-1,beta-lactamase_39,P62593,0.988759,NO,172,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.998,-3.35,2.352,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.0495842,0.00312594,0.988759 beta-lactamase_625_R275H,beta-lactamase_625_275,TEM-1,beta-lactamase_625,P62593,0.988764,NO,275,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.213352,0.0141984,0.988764 beta-lactamase_156_T263S,beta-lactamase_156_263,TEM-1,beta-lactamase_156,P62593,0.988774,NO,263,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.111618,0.0110582,0.988774 beta-lactamase_39_D207H,beta-lactamase_39_207,TEM-1,beta-lactamase_39,P62593,0.988778,NO,207,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.064,-3.07,1.006,,0.409,H,A,0.75,0.12,14.511,14.511,77.62,HAH,-1.77033,0.0495842,0.00592942,0.988778 beta-lactamase_M180R,beta-lactamase_180,TEM-1,beta-lactamase,P62593,0.988787,NO,180,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-2.795,-3.843,1.048,4.96809,0.242,,B,1.07,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.221079,0.00552048,0.988787 beta-lactamase_625_L188V,beta-lactamase_625_188,TEM-1,beta-lactamase_625,P62593,0.988794,NO,188,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.166,-3.017,1.851,,,H,A,0.55,-0.3,2.982,,60.14,PHB,-1.47033,0.213352,0.00295687,0.988794 beta-lactamase_0_S233V,beta-lactamase_0_233,TEM-1,beta-lactamase_0,P62593,0.988798,NO,233,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.886,-3.357,1.471,,0.016,E,B,0.27,-1.01,3.579,,77.62,BPO,-1.17267,0.0500837,0.00311415,0.988798 beta-lactamase_156_G142E,beta-lactamase_156_142,TEM-1,beta-lactamase_156,P62593,0.988798,NO,142,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.707,-3.628,2.921,,0.034,,p,0.29,-0.64,0.325,,64.69,OOO,-0.834,0.111618,0.00060149,0.988798 beta-lactamase_39_M184A,beta-lactamase_39_184,TEM-1,beta-lactamase_39,P62593,0.988801,NO,184,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.593,-2.223,0.63,,,H,A,0.55,-0.87,2.893,,62.94,HHH,-1.41,0.0495842,0.00356019,0.988801 PSD95pdz3_G322H,PSD95pdz3_322,PSD95pdz3,PSD95pdz3,P31016,0.988801,NO,322,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.008,-4.362,3.354,5.24791,,,,,16.3275,,,,POH,-1.24867,0.0758425,0.00105821,0.988801 beta-lactamase_156_Q267E,beta-lactamase_156_267,TEM-1,beta-lactamase_156,P62593,0.988802,NO,267,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.111618,0.0102128,0.988802 beta-lactamase_2500_A225K,beta-lactamase_2500_225,TEM-1,beta-lactamase_2500,P62593,0.988806,NO,225,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.845,-2.558,0.713,,1,T,B,0.46,-0.38,0.551,,74.48,OHO,-1.39967,0.361275,0.00465057,0.988806 beta-lactamase_39_A148T,beta-lactamase_39_148,TEM-1,beta-lactamase_39,P62593,0.988809,NO,148,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.757,-2.508,0.751,,0.379,H,A,0.46,-0.55,3.551,,72.73,PHH,-1.40167,0.0495842,0.00547053,0.988809 beta-lactamase_39_A230T,beta-lactamase_39_230,TEM-1,beta-lactamase_39,P62593,0.988813,NO,230,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.154,-3.381,2.227,,0.01,E,B,0.46,-1.17,1.171,,50,HHA,-1.079,0.0495842,0.00516841,0.988813 beta-lactamase_625_D113P,beta-lactamase_625_113,TEM-1,beta-lactamase_625,P62593,0.988814,NO,113,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.829,-3.062,1.233,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.213352,0.00474112,0.988814 beta-lactamase_625_L199P,beta-lactamase_625_199,TEM-1,beta-lactamase_625,P62593,0.988814,NO,199,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-2.942,-2.099,-0.843,,0.832,H,A,0.55,0.42,1.552,,77.62,PHH,-2.32933,0.213352,0.0048649,0.988814 beta-lactamase_39_Y44L,beta-lactamase_39_44,TEM-1,beta-lactamase_39,P62593,0.988817,NO,44,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-2.547,-2.196,-0.351,,,E,B,0.21,-0.45,2.683,,73.78,OHH,-1.86267,0.0495842,0.00426364,0.988817 beta-lactamase_156_L199P,beta-lactamase_156_199,TEM-1,beta-lactamase_156,P62593,0.988818,NO,199,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-2.942,-2.099,-0.843,,0.832,H,A,0.55,0.42,1.552,,77.62,PHH,-2.32933,0.111618,0.0048649,0.988818 beta-lactamase_39_A200Q,beta-lactamase_39_200,TEM-1,beta-lactamase_39,P62593,0.988822,NO,200,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.878,-3.113,1.235,,0.757,H,A,0.46,-0.19,1.54,,77.62,HHP,-2.001,0.0495842,0.0060056,0.988822 beta-lactamase_2500_F70V,beta-lactamase_2500_70,TEM-1,beta-lactamase_2500,P62593,0.988825,NO,70,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.169,-2.579,1.41,,,H,A,0.58,-1.34,1.918,,63.99,PHB,-0.980667,0.361275,0.00193499,0.988825 beta-lactamase_625_D207T,beta-lactamase_625_207,TEM-1,beta-lactamase_625,P62593,0.988825,NO,207,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.064,-2.565,0.501,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.213352,0.00592942,0.988825 beta-lactamase_625_Q267R,beta-lactamase_625_267,TEM-1,beta-lactamase_625,P62593,0.988825,NO,267,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.213352,0.0102128,0.988825 beta-lactamase_39_N50V,beta-lactamase_39_50,TEM-1,beta-lactamase_39,P62593,0.988829,NO,50,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-2.979,-2.913,-0.066,,0.912,T,A,0.61,1.24,10.736,,77.62,HPP,-2.134,0.0495842,0.0047211,0.988829 beta-lactamase_2500_A200H,beta-lactamase_2500_200,TEM-1,beta-lactamase_2500,P62593,0.988835,NO,200,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.878,-4.732,2.854,,0.757,H,A,0.46,-0.19,0.436,,77.62,HHP,-2.001,0.361275,0.0060056,0.988835 beta-lactamase_A276Q,beta-lactamase_276,TEM-1,beta-lactamase,P62593,0.988843,NO,276,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.144,-3.872,2.728,5.1387,0.117,H,A,0.52,-0.84,1.283,,44.06,HHA,-1.47,0.221079,0.0191712,0.988843 beta-lactamase_D207K,beta-lactamase_207,TEM-1,beta-lactamase,P62593,0.988843,NO,207,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.064,-2.897,0.833,5.40404,0.409,H,A,0.23,0.12,1.975,,77.62,HAH,-1.77033,0.221079,0.00592942,0.988843 beta-lactamase_D99M,beta-lactamase_99,TEM-1,beta-lactamase,P62593,0.988843,NO,99,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.191,-3.198,2.007,5.66081,0.402,G,A,0.23,0.36,1.318,,64.69,PAH,-1.794,0.221079,0.00305446,0.988843 beta-lactamase_E108I,beta-lactamase_108,TEM-1,beta-lactamase,P62593,0.988843,NO,108,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.46,-4.133,2.673,5.52079,0.572,G,A,0.52,1.87,1.973,,72.73,PAB,-1.437,0.221079,0.00413372,0.988843 beta-lactamase_E195T,beta-lactamase_195,TEM-1,beta-lactamase,P62593,0.988843,NO,195,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.186,-2.956,0.77,7.28489,1.016,S,A,1.52,0.85,2.583,,77.62,OAH,-2.02,0.221079,0.00496565,0.988843 beta-lactamase_E210C,beta-lactamase_210,TEM-1,beta-lactamase,P62593,0.988843,NO,210,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.319,-4.991,2.672,5.7398,0.476,H,A,0.52,0.75,1.555,,77.62,HAH,-1.88567,0.221079,0.00663582,0.988843 beta-lactamase_E270S,beta-lactamase_270,TEM-1,beta-lactamase,P62593,0.988843,NO,270,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.723,-3.314,1.591,5.33196,0.422,H,A,0.52,1.15,1.745,,64.34,AAB,-1.70933,0.221079,0.00767762,0.988843 beta-lactamase_E46Q,beta-lactamase_46,TEM-1,beta-lactamase,P62593,0.988843,NO,46,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.94,-4.007,2.067,5.36461,0.021,E,B,1.51,0.14,0.373,,59.44,HAH,-2.079,0.221079,0.00427568,0.988843 beta-lactamase_F17F,beta-lactamase_17,TEM-1,beta-lactamase,P62593,0.988843,NO,17,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-2.337,-2.337,,,,,,,,2.192,,67.83,HHO,-2.17733,0.221079,0.00216499,0.988843 beta-lactamase_F17Y,beta-lactamase_17,TEM-1,beta-lactamase,P62593,0.988843,NO,17,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-2.337,-3.889,1.552,,,,,,,2.192,,67.83,HHO,-2.17733,0.221079,0.00216499,0.988843 beta-lactamase_I206Q,beta-lactamase_206,TEM-1,beta-lactamase,P62593,0.988843,NO,206,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-2.429,-2.554,0.125,5.3727,0.173,H,A,1,-0.34,2.061,,77.62,HHA,-1.805,0.221079,0.00528934,0.988843 beta-lactamase_I206R,beta-lactamase_206,TEM-1,beta-lactamase,P62593,0.988843,NO,206,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-2.429,-3.125,0.696,5.3727,0.173,H,A,1,-0.34,2.061,,77.62,HHA,-1.805,0.221079,0.00528934,0.988843 beta-lactamase_I54F,beta-lactamase_54,TEM-1,beta-lactamase,P62593,0.988843,NO,54,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-2.838,-4.242,1.404,5.40541,0.669,E,B,0.77,-0.14,3.946,,73.78,BHH,-2.337,0.221079,0.00403589,0.988843 beta-lactamase_K213H,beta-lactamase_213,TEM-1,beta-lactamase,P62593,0.988843,NO,213,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.81,-4.552,2.742,5.63167,0.67,,A,1.59,0.29,3.924,,67.83,ABH,-1.57767,0.221079,0.00610411,0.988843 beta-lactamase_K284N,beta-lactamase_284,TEM-1,beta-lactamase,P62593,0.988843,NO,284,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.981,-2.681,0.7,6.30084,0.848,H,A,1.82,0.67,1.931,,77.62,HBB,-1.82133,0.221079,0.0686156,0.988843 beta-lactamase_K30M,beta-lactamase_30,TEM-1,beta-lactamase,P62593,0.988843,NO,30,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-2.307,-4.578,2.271,5.30605,0.142,H,A,1.82,-0.65,2.434,,93.01,HBH,-2.32833,0.221079,0.00448593,0.988843 beta-lactamase_L199A,beta-lactamase_199,TEM-1,beta-lactamase,P62593,0.988843,NO,199,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-2.942,-2.055,-0.887,5.57712,0.832,H,A,0.82,0.42,15.302,15.302,77.62,PHH,-2.32933,0.221079,0.0048649,0.988843 beta-lactamase_Q274H,beta-lactamase_274,TEM-1,beta-lactamase,P62593,0.988843,NO,274,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.082,-2.767,0.685,5.6671,0.066,H,A,0.11,-0.27,2.354,,64.69,BPH,-1.931,0.221079,0.0110418,0.988843 beta-lactamase_Q274Y,beta-lactamase_274,TEM-1,beta-lactamase,P62593,0.988843,NO,274,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.082,-4.02,1.938,5.6671,0.066,H,A,0.11,-0.27,2.354,,64.69,BPH,-1.931,0.221079,0.0110418,0.988843 beta-lactamase_Q37I,beta-lactamase_37,TEM-1,beta-lactamase,P62593,0.988843,NO,37,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.134,-4.024,1.89,5.69153,0.613,H,A,0.12,1.98,1.318,,73.08,APH,-2.06967,0.221079,0.00425833,0.988843 beta-lactamase_S51N,beta-lactamase_51,TEM-1,beta-lactamase,P62593,0.988843,NO,51,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.526,-2.556,1.03,5.06164,0.496,T,A,0.25,0.26,1.699,,72.73,PPO,-1.88467,0.221079,0.00504821,0.988843 beta-lactamase_39_D207L,beta-lactamase_39_207,TEM-1,beta-lactamase_39,P62593,0.98885,NO,207,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.064,-3.704,1.64,,0.409,H,A,0.75,0.12,14.511,14.511,77.62,HAH,-1.77033,0.0495842,0.00592942,0.98885 beta-lactamase_156_A123G,beta-lactamase_156_123,TEM-1,beta-lactamase_156,P62593,0.988857,NO,123,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.834,-2.991,2.157,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.111618,0.0010157,0.988857 beta-lactamase_156_E175Q,beta-lactamase_156_175,TEM-1,beta-lactamase_156,P62593,0.988857,NO,175,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.336,-3.092,0.756,,0.551,,A,1.04,1.05,2.334,,77.62,AAB,-1.31233,0.111618,0.00482205,0.988857 beta-lactamase_2500_A247C,beta-lactamase_2500_247,TEM-1,beta-lactamase_2500,P62593,0.988864,NO,247,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.361275,0.00611275,0.988864 beta-lactamase_156_F58Y,beta-lactamase_156_58,TEM-1,beta-lactamase_156,P62593,0.988865,NO,58,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-2.914,-1.89,-1.024,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.111618,0.00523369,0.988865 beta-lactamase_625_E175D,beta-lactamase_625_175,TEM-1,beta-lactamase_625,P62593,0.988865,NO,175,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.336,-2.916,0.58,,0.551,,A,1.04,1.05,8.527,8.527,77.62,AAB,-1.31233,0.213352,0.00482205,0.988865 beta-lactamase_625_I171S,beta-lactamase_625_171,TEM-1,beta-lactamase_625,P62593,0.988867,NO,171,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-2.431,-2.869,0.438,,0.361,,B,0.48,0.53,3.869,,77.62,HHO,-1.55533,0.213352,0.00623355,0.988867 beta-lactamase_625_T126G,beta-lactamase_625_126,TEM-1,beta-lactamase_625,P62593,0.988867,NO,126,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.122,-2.22,1.098,,0.05,H,A,0.22,-0.05,0.817,,44.41,HPH,-1.60467,0.213352,0.00244552,0.988867 beta-lactamase_39_Q203L,beta-lactamase_39_203,TEM-1,beta-lactamase_39,P62593,0.988879,NO,203,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.168,-2.697,0.529,,0.47,H,A,0.64,-0.38,1.453,,65.38,BPP,-1.614,0.0495842,0.00631514,0.988879 beta-lactamase_156_V82K,beta-lactamase_156_82,TEM-1,beta-lactamase_156,P62593,0.98888,NO,82,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.325,-3.754,2.429,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.111618,0.00397046,0.98888 beta-lactamase_156_R63A,beta-lactamase_156_63,TEM-1,beta-lactamase_156,P62593,0.988883,NO,63,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-0.943,-3.103,2.16,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.111618,0.00126938,0.988883 beta-lactamase_156_E238M,beta-lactamase_156_238,TEM-1,beta-lactamase_156,P62593,0.988888,NO,238,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.111618,0.00743256,0.988888 beta-lactamase_625_G141K,beta-lactamase_625_141,TEM-1,beta-lactamase_625,P62593,0.988911,NO,141,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.828,-3.62,2.792,,0.575,T,l,0.29,-0.28,0.198,,64.69,HOO,-1.08933,0.213352,0.0012419,0.988911 beta-lactamase_156_E61Y,beta-lactamase_156_61,TEM-1,beta-lactamase_156,P62593,0.988921,NO,61,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.115,-4.403,2.288,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.111618,0.00440955,0.988921 beta-lactamase_39_G243A,beta-lactamase_39_243,TEM-1,beta-lactamase_39,P62593,0.988931,NO,243,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.0495842,0.00464034,0.988931 Pab1_K180I,Pab1_180,Pab1,Pab1,P04147,0.988933,NO,180,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.945,-3.836,1.891,,,,,,,,,,HBA,-1.575,0.175299,0.00295933,0.988933 beta-lactamase_156_G39P,beta-lactamase_156_39,TEM-1,beta-lactamase_156,P62593,0.988937,NO,39,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.864,-3.073,1.209,,0.701,T,L,0.29,0.47,1.454,,77.62,HOH,-1.53633,0.111618,0.00487611,0.988937 beta-lactamase_156_H287D,beta-lactamase_156_287,TEM-1,beta-lactamase_156,P62593,0.988943,NO,287,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,,,,,,,,,,,,,BBH,-1.111,0.111618,,0.988943 beta-lactamase_156_Q86P,beta-lactamase_156_86,TEM-1,beta-lactamase_156,P62593,0.98895,NO,86,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.4,-3.985,1.585,,0.696,S,A,0.64,2.38,27.704,27.704,77.62,OPA,-1.61067,0.111618,0.00450027,0.98895 beta-lactamase_39_G142S,beta-lactamase_39_142,TEM-1,beta-lactamase_39,P62593,0.988951,NO,142,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.707,-2.438,1.731,,0.034,,p,0.29,-0.64,1.947,,64.69,OOO,-0.834,0.0495842,0.00060149,0.988951 beta-lactamase_39_R189A,beta-lactamase_39_189,TEM-1,beta-lactamase_39,P62593,0.988952,NO,189,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.844,-2.739,0.895,,0.278,H,A,1.2,1.01,12.11,12.11,72.73,HBB,-1.668,0.0495842,0.0050699,0.988952 beta-lactamase_625_R92T,beta-lactamase_625_92,TEM-1,beta-lactamase_625,P62593,0.988952,NO,92,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.718,-2.88,1.162,,0.479,E,B,1.2,1.36,3.069,,65.38,BBH,-1.50367,0.213352,0.00429626,0.988952 beta-lactamase_R91R,beta-lactamase_91,TEM-1,beta-lactamase,P62593,0.988957,NO,91,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.392,-1.392,,5.92536,0.444,,B,0.68,0.96,1.318,,50.35,OBB,-1.73367,0.221079,0.00380226,0.988957 beta-lactamase_156_T139G,beta-lactamase_156_139,TEM-1,beta-lactamase_156,P62593,0.988965,NO,139,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.901,-3.413,1.512,,0.216,H,A,0.22,0.39,16.34,16.34,77.62,PPH,-2.04667,0.111618,0.00441837,0.988965 Pab1_N187E,Pab1_187,Pab1,Pab1,P04147,0.988965,NO,187,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-1.224,-2.955,1.731,,0.456,S,b,,1.87,,,,HPO,-1.272,0.175299,0.00083165,0.988965 beta-lactamase_2500_N50P,beta-lactamase_2500_50,TEM-1,beta-lactamase_2500,P62593,0.988979,NO,50,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-2.979,-3.95,0.971,,0.912,T,A,0.61,1.24,1.581,,77.62,HPP,-2.134,0.361275,0.0047211,0.988979 beta-lactamase_156_L167N,beta-lactamase_156_167,TEM-1,beta-lactamase_156,P62593,0.988981,NO,167,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.138,-4.008,2.87,,0.015,G,A,0.55,-0.63,0.4,,64.69,AHP,-1.30767,0.111618,0.00303566,0.988981 beta-lactamase_156_D207A,beta-lactamase_156_207,TEM-1,beta-lactamase_156,P62593,0.988983,NO,207,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.064,-2.585,0.521,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.111618,0.00592942,0.988983 kka2_1:4_L67M,kka2_1:4_67,Kka2,kka2_1:4,P00552,0.988985,NO,67,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.741,-3.833,3.092,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.168804,0.00102787,0.988985 beta-lactamase_156_A246S,beta-lactamase_156_246,TEM-1,beta-lactamase_156,P62593,0.988988,NO,246,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.121,-3.607,1.486,,0.01,E,B,0.46,-1.01,1.959,,73.78,HHH,-1.55633,0.111618,0.00569458,0.988988 beta-lactamase_625_L199C,beta-lactamase_625_199,TEM-1,beta-lactamase_625,P62593,0.98899,NO,199,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-2.942,-5.078,2.136,,0.832,H,A,0.55,0.42,1.552,,77.62,PHH,-2.32933,0.213352,0.0048649,0.98899 beta-lactamase_39_Q276H,beta-lactamase_39_276,TEM-1,beta-lactamase_39,P62593,0.989001,NO,276,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.0495842,0.0191712,0.989001 beta-lactamase_625_L150N,beta-lactamase_625_150,TEM-1,beta-lactamase_625,P62593,0.98901,NO,150,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.326,-4.088,2.762,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.213352,0.00463171,0.98901 beta-lactamase_156_L167G,beta-lactamase_156_167,TEM-1,beta-lactamase_156,P62593,0.989012,NO,167,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.138,-3.694,2.556,,0.015,G,A,0.55,-0.63,0.4,,64.69,AHP,-1.30767,0.111618,0.00303566,0.989012 beta-lactamase_39_K144N,beta-lactamase_39_144,TEM-1,beta-lactamase_39,P62593,0.989013,NO,144,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-2.388,-3.043,0.655,,0.863,H,A,2.34,1.27,14.556,14.556,77.62,OBA,-1.904,0.0495842,0.00481141,0.989013 gb1_K239Q,gb1_239,gb1,gb1,P06654,0.989013,NO,239,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-3.043,-3.485,0.442,,,,,,,1.326,,45.54,HBO,-2.31467,0.177985,0.00207004,0.989013 beta-lactamase_39_L79G,beta-lactamase_39_79,TEM-1,beta-lactamase_39,P62593,0.989015,NO,79,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.842,-3.806,2.964,,0.007,H,A,0.55,-0.16,0.823,,50.35,HHP,-1.44333,0.0495842,0.000947397,0.989015 beta-lactamase_156_I206G,beta-lactamase_156_206,TEM-1,beta-lactamase_156,P62593,0.989019,NO,206,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-2.429,-2.667,0.238,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.111618,0.00528934,0.989019 WW_domain_I193M,WW_domain_193,Yap65,WW_domain,P46937,0.989029,NO,193,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.993,-2.947,0.954,6.15906,,,,,,1.833,,83.33,BHA,-1.756,0.153962,0.00587613,0.989029 beta-lactamase_39_V157M,beta-lactamase_39_157,TEM-1,beta-lactamase_39,P62593,0.989041,NO,157,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.751,-2.587,0.836,,0.308,S,a,0.44,-0.75,10.364,10.364,69.58,BHP,-2.00767,0.0495842,0.00506849,0.989041 beta-lactamase_156_S241D,beta-lactamase_156_241,TEM-1,beta-lactamase_156,P62593,0.989047,NO,241,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.111618,0.00452736,0.989047 beta-lactamase_39_P224I,beta-lactamase_39_224,TEM-1,beta-lactamase_39,P62593,0.989049,NO,224,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.893,-4.034,3.141,,0.383,,B,0.52,-0.3,3.169,,74.48,HOH,-1.26433,0.0495842,0.00189564,0.989049 beta-lactamase_625_T126K,beta-lactamase_625_126,TEM-1,beta-lactamase_625,P62593,0.98905,NO,126,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.122,-3.536,2.414,,0.05,H,A,0.22,-0.05,0.817,,44.41,HPH,-1.60467,0.213352,0.00244552,0.98905 beta-lactamase_156_N152T,beta-lactamase_156_152,TEM-1,beta-lactamase_156,P62593,0.989052,NO,152,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-2.757,-2.377,-0.38,,0.863,H,A,0.61,0.92,4.038,,77.62,BPH,-2.97,0.111618,0.00471429,0.989052 beta-lactamase_2500_I140M,beta-lactamase_2500_140,TEM-1,beta-lactamase_2500,P62593,0.989056,NO,140,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.733,-4.137,2.404,,0.128,H,A,0.48,0.41,1.628,,73.08,PHO,-1.48733,0.361275,0.00597777,0.989056 beta-lactamase_0_S51A,beta-lactamase_0_51,TEM-1,beta-lactamase_0,P62593,0.98906,NO,51,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.526,-2.32,0.794,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.0500837,0.00504821,0.98906 beta-lactamase_2500_T269A,beta-lactamase_2500_269,TEM-1,beta-lactamase_2500,P62593,0.989064,NO,269,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.361275,0.00950944,0.989064 beta-lactamase_2500_R92I,beta-lactamase_2500_92,TEM-1,beta-lactamase_2500,P62593,0.989066,NO,92,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.718,-3.773,2.055,,0.479,E,B,1.2,1.36,3.069,,65.38,BBH,-1.50367,0.361275,0.00429626,0.989066 beta-lactamase_156_G90R,beta-lactamase_156_90,TEM-1,beta-lactamase_156,P62593,0.989067,NO,90,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-2.091,-3.098,1.007,,0.598,T,A,0.29,0.32,0.319,,77.62,HOB,-1.52633,0.111618,0.00490273,0.989067 beta-lactamase_625_L55S,beta-lactamase_625_55,TEM-1,beta-lactamase_625,P62593,0.989072,NO,55,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.86,-3.706,1.846,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.213352,0.00403741,0.989072 Pab1_N192S,Pab1_192,Pab1,Pab1,P04147,0.989073,NO,192,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-1.079,-2.753,1.674,,0.619,T,l,,2.28,,,,HPO,-1.231,0.175299,0.000273498,0.989073 kka2_1:8_G151Y,kka2_1:8_151,Kka2,kka2_1:8,P00552,0.989076,NO,151,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.873,-4.442,3.569,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.100394,0.00339918,0.989076 kka2_1:8_G151Y,kka2_1:8_151,Kka2,kka2_1:8,P00552,0.989076,NO,151,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.873,-4.442,3.569,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.100394,0.00339918,0.989076 beta-lactamase_156_S266I,beta-lactamase_156_266,TEM-1,beta-lactamase_156,P62593,0.989077,NO,266,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.111618,0.0140785,0.989077 beta-lactamase_625_P224K,beta-lactamase_625_224,TEM-1,beta-lactamase_625,P62593,0.989086,NO,224,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.893,-3.389,2.496,,0.383,,B,0.52,-0.3,1.35,,74.48,HOH,-1.26433,0.213352,0.00189564,0.989086 beta-lactamase_39_G52L,beta-lactamase_39_52,TEM-1,beta-lactamase_39,P62593,0.989089,NO,52,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.149,-3.755,2.606,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.0495842,0.00340138,0.989089 beta-lactamase_P172V,beta-lactamase_172,TEM-1,beta-lactamase,P62593,0.98909,NO,172,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.998,-3.483,2.485,5.98941,0.639,T,b,1.1,0.24,2.087,,74.48,HOP,-2.03067,0.221079,0.00312594,0.98909 beta-lactamase_39_A268V,beta-lactamase_39_268,TEM-1,beta-lactamase_39,P62593,0.989098,NO,268,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.0495842,0.0102525,0.989098 beta-lactamase_39_A247H,beta-lactamase_39_247,TEM-1,beta-lactamase_39,P62593,0.989114,NO,247,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.0495842,0.00611275,0.989114 beta-lactamase_39_I54S,beta-lactamase_39_54,TEM-1,beta-lactamase_39,P62593,0.989114,NO,54,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-2.838,-3.459,0.621,,0.669,E,B,0.48,-0.14,1.349,,73.78,BHH,-2.337,0.0495842,0.00403589,0.989114 kka2_1:1_A14T,kka2_1:1_14,Kka2,kka2_1:1,P00552,0.989115,NO,14,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.837,-2.286,0.449,,0.728,G,A,0.46,0.7,1.17,,71.59,HHH,-1.82567,0.520039,0.00706614,0.989115 beta-lactamase_156_R257C,beta-lactamase_156_257,TEM-1,beta-lactamase_156,P62593,0.989117,NO,257,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.111618,0.00756629,0.989117 beta-lactamase_2500_S233T,beta-lactamase_2500_233,TEM-1,beta-lactamase_2500,P62593,0.989117,NO,233,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.886,-1.229,-0.657,,0.016,E,B,0.27,-1.01,2.851,,77.62,BPO,-1.17267,0.361275,0.00311415,0.989117 beta-lactamase_625_Q276M,beta-lactamase_625_276,TEM-1,beta-lactamase_625,P62593,0.989117,NO,276,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.213352,0.0191712,0.989117 beta-lactamase_156_A148P,beta-lactamase_156_148,TEM-1,beta-lactamase_156,P62593,0.989121,NO,148,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.757,-3.925,2.168,,0.379,H,A,0.46,-0.55,3.551,,72.73,PHH,-1.40167,0.111618,0.00547053,0.989121 beta-lactamase_625_H94P,beta-lactamase_625_94,TEM-1,beta-lactamase_625,P62593,0.989126,NO,94,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-2.5,-2.499,-0.001,,0.776,,B,0.17,1.24,19.42,19.42,77.62,HBH,-1.872,0.213352,0.00389226,0.989126 beta-lactamase_39_R257G,beta-lactamase_39_257,TEM-1,beta-lactamase_39,P62593,0.989127,NO,257,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.0495842,0.00756629,0.989127 Pab1_F173Y,Pab1_173,Pab1,Pab1,P04147,0.989128,NO,173,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.477,-1.616,0.139,,,E,B,0.87,-0.16,1.636,,63.26,BHA,-1.36967,0.175299,0.00148779,0.989128 beta-lactamase_39_G114V,beta-lactamase_39_114,TEM-1,beta-lactamase_39,P62593,0.989129,NO,114,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.094,-3.65,2.556,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.0495842,0.00224919,0.989129 beta-lactamase_156_G85V,beta-lactamase_156_85,TEM-1,beta-lactamase_156,P62593,0.989137,NO,85,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.011,-3.796,2.785,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.111618,0.00252173,0.989137 beta-lactamase_E270V,beta-lactamase_270,TEM-1,beta-lactamase,P62593,0.989137,NO,270,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.723,-2.886,1.163,5.33196,0.422,H,A,0.52,1.15,1.745,,64.34,AAB,-1.70933,0.221079,0.00767762,0.989137 beta-lactamase_39_L100T,beta-lactamase_39_100,TEM-1,beta-lactamase_39,P62593,0.989144,NO,100,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.218,-3.502,2.284,,0.343,,B,0.55,0.13,8.311,,63.29,AHH,-1.23467,0.0495842,0.00413885,0.989144 beta-lactamase_39_K286A,beta-lactamase_39_286,TEM-1,beta-lactamase_39,P62593,0.989147,NO,286,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.0495842,,0.989147 beta-lactamase_156_G90I,beta-lactamase_156_90,TEM-1,beta-lactamase_156,P62593,0.98915,NO,90,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-2.091,-4.052,1.961,,0.598,T,A,0.29,0.32,0.319,,77.62,HOB,-1.52633,0.111618,0.00490273,0.98915 beta-lactamase_2500_A282I,beta-lactamase_2500_282,TEM-1,beta-lactamase_2500,P62593,0.989152,NO,282,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.361275,0.0449821,0.989152 kka2_1:2_A56R,kka2_1:2_56,Kka2,kka2_1:2,P00552,0.989153,NO,56,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.083,-3.254,1.171,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.295029,0.00717715,0.989153 kka2_1:2_V80A,kka2_1:2_80,Kka2,kka2_1:2,P00552,0.989153,NO,80,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.144,-2.287,1.143,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.295029,0.00488211,0.989153 beta-lactamase_39_L135R,beta-lactamase_39_135,TEM-1,beta-lactamase_39,P62593,0.989155,NO,135,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.002,-4.002,3,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.0495842,0.00244423,0.989155 PSD95pdz3_K380C,PSD95pdz3_380,PSD95pdz3,PSD95pdz3,P31016,0.989157,NO,380,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.416,-4.769,3.353,5.87979,,,,,19.6722,,,,HBP,-1.391,0.0758425,0.000281399,0.989157 beta-lactamase_625_N98T,beta-lactamase_625_98,TEM-1,beta-lactamase_625,P62593,0.989159,NO,98,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-2.973,-2.907,-0.066,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.213352,0.00505389,0.989159 beta-lactamase_625_Y103P,beta-lactamase_625_103,TEM-1,beta-lactamase_625,P62593,0.98916,NO,103,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-1.33,-4.138,2.808,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.213352,0.00443048,0.98916 Pab1_E176V,Pab1_176,Pab1,Pab1,P04147,0.989166,NO,176,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.003,-3.502,1.499,,,,,,,,,,AAO,-2.09933,0.175299,0.00264426,0.989166 beta-lactamase_156_R242N,beta-lactamase_156_242,TEM-1,beta-lactamase_156,P62593,0.989173,NO,242,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.111618,0.00452879,0.989173 beta-lactamase_625_L160H,beta-lactamase_625_160,TEM-1,beta-lactamase_625,P62593,0.989173,NO,160,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.977,-4.948,3.971,,0.022,,B,0.55,-0.6,0.237,,44.41,BHA,-0.936,0.213352,0.00193775,0.989173 beta-lactamase_A246C,beta-lactamase_246,TEM-1,beta-lactamase,P62593,0.989174,NO,246,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.121,-3.242,1.121,4.78979,0.01,E,B,0.52,-1.01,1.26,,73.78,HHH,-1.55633,0.221079,0.00569458,0.989174 beta-lactamase_156_T198G,beta-lactamase_156_198,TEM-1,beta-lactamase_156,P62593,0.989175,NO,198,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.168,-3.295,1.127,,0.489,,B,0.22,-0.13,10.771,10.771,73.78,HPH,-1.98767,0.111618,0.004311,0.989175 beta-lactamase_2500_L135V,beta-lactamase_2500_135,TEM-1,beta-lactamase_2500,P62593,0.989183,NO,135,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.002,-2.8,1.798,,0.117,H,A,0.55,-0.58,0.795,,43.71,PHH,-1.03767,0.361275,0.00244423,0.989183 Pab1_N187L,Pab1_187,Pab1,Pab1,P04147,0.989183,NO,187,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-1.224,-3.504,2.28,,0.456,S,b,,1.87,,,,HPO,-1.272,0.175299,0.00083165,0.989183 beta-lactamase_156_D231L,beta-lactamase_156_231,TEM-1,beta-lactamase_156,P62593,0.989185,NO,231,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.816,-3.806,2.99,,,E,B,0.75,-1.06,2.66,,65.38,HAB,-0.994,0.111618,0.00107395,0.989185 gb1_N234E,gb1_234,gb1,gb1,P06654,0.989185,NO,234,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-2.055,-2.952,0.897,,,,,,,1.235,,45.54,HPO,-2.05067,0.177985,0.00242189,0.989185 beta-lactamase_625_P165N,beta-lactamase_625_165,TEM-1,beta-lactamase_625,P62593,0.989191,NO,165,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.373,-3.703,2.33,,0.203,T,A,0.52,-0.31,0.414,,73.78,AOA,-1.359,0.213352,0.00549538,0.989191 beta-lactamase_0_S122R,beta-lactamase_0_122,TEM-1,beta-lactamase_0,P62593,0.989195,NO,122,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.406,-3.131,0.725,,0.352,H,A,0.27,-0.54,30.794,30.794,77.62,OPH,-1.39767,0.0500837,0.00497825,0.989195 beta-lactamase_625_A183D,beta-lactamase_625_183,TEM-1,beta-lactamase_625,P62593,0.989199,NO,183,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.231,-2.686,1.455,,0.155,H,A,0.46,-0.91,23.859,23.859,77.62,HHH,-1.53367,0.213352,0.00296631,0.989199 beta-lactamase_156_H156E,beta-lactamase_156_156,TEM-1,beta-lactamase_156,P62593,0.989201,NO,156,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-3.156,-2.577,-0.579,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.111618,0.00468596,0.989201 beta-lactamase_625_S80Y,beta-lactamase_625_80,TEM-1,beta-lactamase_625,P62593,0.989201,NO,80,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.029,-4.297,2.268,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.213352,0.00565569,0.989201 beta-lactamase_156_L160N,beta-lactamase_156_160,TEM-1,beta-lactamase_156,P62593,0.989202,NO,160,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.977,-4.165,3.188,,0.022,,B,0.55,-0.6,1.095,,44.41,BHA,-0.936,0.111618,0.00193775,0.989202 kka2_1:2_Q136M,kka2_1:2_136,Kka2,kka2_1:2,P00552,0.989208,NO,136,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-3.021,-4.715,1.694,,0.331,,b,0.4,0.96,2.726,,92.05,BPH,-2.16933,0.295029,0.00624149,0.989208 beta-lactamase_39_L205M,beta-lactamase_39_205,TEM-1,beta-lactamase_39,P62593,0.989211,NO,205,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.922,-3.889,2.967,,,H,A,0.55,-0.46,0.846,,42.31,PHH,-1.57767,0.0495842,0.00255802,0.989211 beta-lactamase_2500_E26M,beta-lactamase_2500_26,TEM-1,beta-lactamase_2500,P62593,0.989215,NO,26,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.454,-4.568,2.114,,0.54,H,A,1.04,0.98,0.49,,93.01,OAP,-1.96167,0.361275,0.00297948,0.989215 Pab1_G193L,Pab1_193,Pab1,Pab1,P04147,0.989218,NO,193,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.414,-3.693,2.279,,,,,,,,,,POP,-1.55733,0.175299,0.0014922,0.989218 beta-lactamase_2500_N50R,beta-lactamase_2500_50,TEM-1,beta-lactamase_2500,P62593,0.989223,NO,50,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-2.979,-3.883,0.904,,0.912,T,A,0.61,1.24,1.581,,77.62,HPP,-2.134,0.361275,0.0047211,0.989223 beta-lactamase_39_K286D,beta-lactamase_39_286,TEM-1,beta-lactamase_39,P62593,0.989225,NO,286,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.0495842,,0.989225 beta-lactamase_2500_Q86E,beta-lactamase_2500_86,TEM-1,beta-lactamase_2500,P62593,0.989228,NO,86,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.4,-2.379,-0.021,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.361275,0.00450027,0.989228 beta-lactamase_625_L111N,beta-lactamase_625_111,TEM-1,beta-lactamase_625,P62593,0.989231,NO,111,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.76,-4.132,2.372,,0.328,T,A,0.55,0.93,2.26,,64.34,BHP,-1.884,0.213352,0.00480671,0.989231 beta-lactamase_625_P224E,beta-lactamase_625_224,TEM-1,beta-lactamase_625,P62593,0.989234,NO,224,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.893,-3.439,2.546,,0.383,,B,0.52,-0.3,1.35,,74.48,HOH,-1.26433,0.213352,0.00189564,0.989234 beta-lactamase_2500_G90H,beta-lactamase_2500_90,TEM-1,beta-lactamase_2500,P62593,0.989237,NO,90,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-2.091,-3.353,1.262,,0.598,T,A,0.29,0.32,1.2,,77.62,HOB,-1.52633,0.361275,0.00490273,0.989237 beta-lactamase_0_Q37D,beta-lactamase_0_37,TEM-1,beta-lactamase_0,P62593,0.989238,NO,37,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.134,-2.904,0.77,,0.613,H,A,0.64,1.98,4.001,,73.08,APH,-2.06967,0.0500837,0.00425833,0.989238 beta-lactamase_156_Q276H,beta-lactamase_156_276,TEM-1,beta-lactamase_156,P62593,0.989246,NO,276,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.111618,0.0191712,0.989246 beta-lactamase_2500_L73V,beta-lactamase_2500_73,TEM-1,beta-lactamase_2500,P62593,0.989247,NO,73,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.507,-2.286,0.779,,,H,A,0.55,-0.64,2.178,,67.83,HHH,-1.487,0.361275,0.00488983,0.989247 beta-lactamase_156_L167V,beta-lactamase_156_167,TEM-1,beta-lactamase_156,P62593,0.989254,NO,167,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.138,-2.277,1.139,,0.015,G,A,0.55,-0.63,0.4,,64.69,AHP,-1.30767,0.111618,0.00303566,0.989254 beta-lactamase_39_G249R,beta-lactamase_39_249,TEM-1,beta-lactamase_39,P62593,0.989254,NO,249,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.312,,,,0.256,S,B,0.23,0.04,30.841,30.841,72.73,HOO,-1.81367,0.0495842,0.00220169,0.989254 beta-lactamase_2500_S256C,beta-lactamase_2500_256,TEM-1,beta-lactamase_2500,P62593,0.98926,NO,256,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.361275,0.00710634,0.98926 beta-lactamase_39_T193C,beta-lactamase_39_193,TEM-1,beta-lactamase_39,P62593,0.989264,NO,193,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.914,-4.857,2.943,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.0495842,0.00482669,0.989264 beta-lactamase_2500_T269D,beta-lactamase_2500_269,TEM-1,beta-lactamase_2500,P62593,0.989271,NO,269,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.156,-3.518,1.362,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.361275,0.00950944,0.989271 beta-lactamase_625_H287R,beta-lactamase_625_287,TEM-1,beta-lactamase_625,P62593,0.98928,NO,287,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,,,,,,,,,,,,,BBH,-1.111,0.213352,,0.98928 beta-lactamase_K53E,beta-lactamase_53,TEM-1,beta-lactamase,P62593,0.989287,NO,53,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-2.313,-2.655,0.342,5.93654,0.589,,B,1.82,1.15,19.72,19.72,77.62,OBH,-2.1,0.221079,0.00383383,0.989287 beta-lactamase_625_T264Y,beta-lactamase_625_264,TEM-1,beta-lactamase_625,P62593,0.989288,NO,264,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.213352,0.0119399,0.989288 beta-lactamase_156_Q37A,beta-lactamase_156_37,TEM-1,beta-lactamase_156,P62593,0.989289,NO,37,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.134,-2.542,0.408,,0.613,H,A,0.64,1.98,12.052,12.052,73.08,APH,-2.06967,0.111618,0.00425833,0.989289 beta-lactamase_39_A268E,beta-lactamase_39_268,TEM-1,beta-lactamase_39,P62593,0.989289,NO,268,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.0495842,0.0102525,0.989289 beta-lactamase_39_A268M,beta-lactamase_39_268,TEM-1,beta-lactamase_39,P62593,0.989289,NO,268,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.023,-2.456,0.433,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.0495842,0.0102525,0.989289 beta-lactamase_0_K286E,beta-lactamase_0_286,TEM-1,beta-lactamase_0,P62593,0.98929,NO,286,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.0500837,,0.98929 beta-lactamase_2500_H156Q,beta-lactamase_2500_156,TEM-1,beta-lactamase_2500,P62593,0.9893,NO,156,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-3.156,-2.776,-0.38,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.361275,0.00468596,0.9893 beta-lactamase_156_P105G,beta-lactamase_156_105,TEM-1,beta-lactamase_156,P62593,0.989303,NO,105,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.813,-3.321,2.508,,0.226,T,A,0.52,0.8,1.154,,63.29,POH,-1.01533,0.111618,0.0011981,0.989303 beta-lactamase_625_I171F,beta-lactamase_625_171,TEM-1,beta-lactamase_625,P62593,0.989303,NO,171,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-2.431,-3.175,0.744,,0.361,,B,0.48,0.53,3.869,,77.62,HHO,-1.55533,0.213352,0.00623355,0.989303 beta-lactamase_2500_Q276S,beta-lactamase_2500_276,TEM-1,beta-lactamase_2500,P62593,0.989304,NO,276,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.361275,0.0191712,0.989304 beta-lactamase_39_G39V,beta-lactamase_39_39,TEM-1,beta-lactamase_39,P62593,0.989304,NO,39,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.864,-3.813,1.949,,0.701,T,L,0.29,0.47,1.454,,77.62,HOH,-1.53633,0.0495842,0.00487611,0.989304 beta-lactamase_2500_S57G,beta-lactamase_2500_57,TEM-1,beta-lactamase_2500,P62593,0.989305,NO,57,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.918,-2.176,0.258,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.361275,0.00492804,0.989305 beta-lactamase_156_Q88F,beta-lactamase_156_88,TEM-1,beta-lactamase_156,P62593,0.989308,NO,88,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.086,-4.377,2.291,,0.807,,B,0.64,2.03,0.911,,77.62,APH,-1.53433,0.111618,0.00504167,0.989308 beta-lactamase_156_D83G,beta-lactamase_156_83,TEM-1,beta-lactamase_156,P62593,0.989313,NO,83,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.066,-2.429,1.363,,0.354,H,A,0.75,0.22,1.281,,48.95,HAH,-1.34733,0.111618,0.00205968,0.989313 beta-lactamase_39_I285Q,beta-lactamase_39_285,TEM-1,beta-lactamase_39,P62593,0.989316,NO,285,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.0495842,0.101555,0.989316 beta-lactamase_625_V42W,beta-lactamase_625_42,TEM-1,beta-lactamase_625,P62593,0.989319,NO,42,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.564,-5.336,3.772,,0.017,E,B,0.44,-0.51,2.576,,63.99,BHO,-1.042,0.213352,0.00404515,0.989319 PSD95pdz3_I388V,PSD95pdz3_388,PSD95pdz3,PSD95pdz3,P31016,0.989321,NO,388,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.63,-2.085,0.455,5.17282,,,,,16.0025,,,,PHH,-1.54967,0.0758425,0.000151216,0.989321 beta-lactamase_625_P172S,beta-lactamase_625_172,TEM-1,beta-lactamase_625,P62593,0.989323,NO,172,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.998,-2.394,1.396,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.213352,0.00312594,0.989323 beta-lactamase_39_E279M,beta-lactamase_39_279,TEM-1,beta-lactamase_39,P62593,0.989327,NO,279,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.0495842,0.0192826,0.989327 beta-lactamase_625_N98R,beta-lactamase_625_98,TEM-1,beta-lactamase_625,P62593,0.989333,NO,98,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-2.973,-2.618,-0.355,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.213352,0.00505389,0.989333 beta-lactamase_39_A222P,beta-lactamase_39_222,TEM-1,beta-lactamase_39,P62593,0.989336,NO,222,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.103,-2.971,0.868,,0.233,H,A,0.46,-0.25,1.448,,77.62,PHH,-1.63733,0.0495842,0.00466094,0.989336 beta-lactamase_39_L28S,beta-lactamase_39_28,TEM-1,beta-lactamase_39,P62593,0.989341,NO,28,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.579,-3.523,1.944,,0.277,H,A,0.55,-0.16,3.262,,93.01,PHH,-2.11333,0.0495842,0.00359321,0.989341 beta-lactamase_39_D177G,beta-lactamase_39_177,TEM-1,beta-lactamase_39,P62593,0.989342,NO,177,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.967,-2.392,1.425,,0.006,T,L,0.75,-1.02,3.536,,64.69,BAP,-0.873667,0.0495842,0.000864022,0.989342 beta-lactamase_2500_D252L,beta-lactamase_2500_252,TEM-1,beta-lactamase_2500,P62593,0.989344,NO,252,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.94,,,,0.766,,B,1.59,1.16,,,67.83,OAO,-2.0965,0.361275,0.00575769,0.989344 beta-lactamase_K109N,beta-lactamase_109,TEM-1,beta-lactamase,P62593,0.989344,NO,109,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.734,-2.767,1.033,6.05842,0.787,G,A,1.82,2.21,21.623,21.623,72.73,ABB,-1.63333,0.221079,0.00462493,0.989344 beta-lactamase_625_T147V,beta-lactamase_625_147,TEM-1,beta-lactamase_625,P62593,0.989356,NO,147,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.149,-3.22,2.071,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.213352,0.00226017,0.989356 beta-lactamase_2500_K53Q,beta-lactamase_2500_53,TEM-1,beta-lactamase_2500,P62593,0.989359,NO,53,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-2.313,-2.642,0.329,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.361275,0.00383383,0.989359 beta-lactamase_156_E175V,beta-lactamase_156_175,TEM-1,beta-lactamase_156,P62593,0.989361,NO,175,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.336,-2.38,0.044,,0.551,,A,1.04,1.05,2.334,,77.62,AAB,-1.31233,0.111618,0.00482205,0.989361 beta-lactamase_2500_I244V,beta-lactamase_2500_244,TEM-1,beta-lactamase_2500,P62593,0.989361,NO,244,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.555,-1.239,-0.316,,,E,B,0.48,-0.84,1.683,,77.62,OHH,-1.385,0.361275,0.00605379,0.989361 beta-lactamase_0_A230S,beta-lactamase_0_230,TEM-1,beta-lactamase_0,P62593,0.989367,NO,230,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.154,-2.48,1.326,,0.01,E,B,0.46,-1.17,2.179,,50,HHA,-1.079,0.0500837,0.00516841,0.989367 beta-lactamase_625_Q276S,beta-lactamase_625_276,TEM-1,beta-lactamase_625,P62593,0.98937,NO,276,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.213352,0.0191712,0.98937 beta-lactamase_39_G154Y,beta-lactamase_39_154,TEM-1,beta-lactamase_39,P62593,0.989377,NO,154,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.823,-4.424,3.601,,0.54,T,l,0.29,-0.56,1.151,,64.69,HOA,-1.635,0.0495842,0.00180205,0.989377 kka2_1:2_Q26V,kka2_1:2_26,Kka2,kka2_1:2,P00552,0.989382,NO,26,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.18,-3.715,1.535,,0.448,E,B,0.4,0.44,5.022,,92.05,HPP,-2.11167,0.295029,0.00708962,0.989382 beta-lactamase_2500_P60T,beta-lactamase_2500_60,TEM-1,beta-lactamase_2500,P62593,0.989384,NO,60,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-2.469,-3.483,1.014,,0.256,T,A,0.52,-0.56,1.581,,77.62,BOA,-1.97633,0.361275,0.00521318,0.989384 beta-lactamase_156_A278D,beta-lactamase_156_278,TEM-1,beta-lactamase_156,P62593,0.989385,NO,278,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.111618,0.0310297,0.989385 beta-lactamase_39_N98W,beta-lactamase_39_98,TEM-1,beta-lactamase_39,P62593,0.989386,NO,98,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-2.973,-5.455,2.482,,0.963,G,A,0.61,1.35,14.853,14.853,77.62,PPA,-2.07867,0.0495842,0.00505389,0.989386 beta-lactamase_39_G52S,beta-lactamase_39_52,TEM-1,beta-lactamase_39,P62593,0.989388,NO,52,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.149,-2.647,1.498,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.0495842,0.00340138,0.989388 beta-lactamase_2500_K254Q,beta-lactamase_2500_254,TEM-1,beta-lactamase_2500,P62593,0.989391,NO,254,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.361275,0.00369,0.989391 beta-lactamase_156_L111C,beta-lactamase_156_111,TEM-1,beta-lactamase_156,P62593,0.989398,NO,111,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.76,-4.796,3.036,,0.328,T,A,0.55,0.93,2.26,,64.34,BHP,-1.884,0.111618,0.00480671,0.989398 beta-lactamase_625_T193E,beta-lactamase_625_193,TEM-1,beta-lactamase_625,P62593,0.9894,NO,193,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.914,-3.756,1.842,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.213352,0.00482669,0.9894 beta-lactamase_39_H287R,beta-lactamase_39_287,TEM-1,beta-lactamase_39,P62593,0.989403,NO,287,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,,,,,,,,,,,,,BBH,-1.111,0.0495842,,0.989403 beta-lactamase_625_T131A,beta-lactamase_625_131,TEM-1,beta-lactamase_625,P62593,0.989405,NO,131,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.328,-2.085,0.757,,,H,A,0.22,-0.69,2.031,,67.48,PPH,-1.00867,0.213352,0.00345886,0.989405 beta-lactamase_39_R176T,beta-lactamase_39_176,TEM-1,beta-lactamase_39,P62593,0.989408,NO,176,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-0.863,-3.421,2.558,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.0495842,0.00105554,0.989408 beta-lactamase_625_R189S,beta-lactamase_625_189,TEM-1,beta-lactamase_625,P62593,0.989408,NO,189,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.844,-2.849,1.005,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.213352,0.0050699,0.989408 beta-lactamase_E277I,beta-lactamase_277,TEM-1,beta-lactamase,P62593,0.989418,NO,277,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.869,-4.006,2.137,5.51786,0.545,H,A,0.52,-0.01,2.022,,77.62,HAH,-1.45367,0.221079,0.0169305,0.989418 beta-lactamase_I206K,beta-lactamase_206,TEM-1,beta-lactamase,P62593,0.989418,NO,206,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-2.429,-3.632,1.203,5.3727,0.173,H,A,1,-0.34,2.061,,77.62,HHA,-1.805,0.221079,0.00528934,0.989418 beta-lactamase_I45T,beta-lactamase_45,TEM-1,beta-lactamase,P62593,0.989418,NO,45,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-2.421,-2.537,0.116,5.31505,,E,B,1,-0.3,2.256,,77.62,HHA,-2.30267,0.221079,0.00452842,0.989418 beta-lactamase_625_A268V,beta-lactamase_625_268,TEM-1,beta-lactamase_625,P62593,0.989419,NO,268,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.213352,0.0102525,0.989419 beta-lactamase_156_P250E,beta-lactamase_156_250,TEM-1,beta-lactamase_156,P62593,0.98942,NO,250,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.111618,0.00550899,0.98942 beta-lactamase_156_L188C,beta-lactamase_156_188,TEM-1,beta-lactamase_156,P62593,0.989424,NO,188,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.166,-4.777,3.611,,,H,A,0.55,-0.3,1.574,,60.14,PHB,-1.47033,0.111618,0.00295687,0.989424 beta-lactamase_625_H287L,beta-lactamase_625_287,TEM-1,beta-lactamase_625,P62593,0.989424,NO,287,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,,,,,,,,,,,,,BBH,-1.111,0.213352,,0.989424 beta-lactamase_2500_T139I,beta-lactamase_2500_139,TEM-1,beta-lactamase_2500,P62593,0.989427,NO,139,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.901,-3.075,1.174,,0.216,H,A,0.22,0.39,2.256,,77.62,PPH,-2.04667,0.361275,0.00441837,0.989427 beta-lactamase_156_S122Y,beta-lactamase_156_122,TEM-1,beta-lactamase_156,P62593,0.989431,NO,122,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.406,-4.156,1.75,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.111618,0.00497825,0.989431 beta-lactamase_625_T264D,beta-lactamase_625_264,TEM-1,beta-lactamase_625,P62593,0.989433,NO,264,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.213352,0.0119399,0.989433 beta-lactamase_625_M127Y,beta-lactamase_625_127,TEM-1,beta-lactamase_625,P62593,0.989438,NO,127,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-2.251,-2.954,0.703,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.213352,0.00437927,0.989438 beta-lactamase_E166V,beta-lactamase_166,TEM-1,beta-lactamase,P62593,0.989448,NO,166,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.756,-2.896,1.14,5.60527,0.508,G,A,0.52,1.05,2.124,,73.08,OAH,-1.42233,0.221079,0.00512989,0.989448 beta-lactamase_2500_H94M,beta-lactamase_2500_94,TEM-1,beta-lactamase_2500,P62593,0.989454,NO,94,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-2.5,-3.474,0.974,,0.776,,B,0.17,1.24,1.176,,77.62,HBH,-1.872,0.361275,0.00389226,0.989454 beta-lactamase_156_R202N,beta-lactamase_156_202,TEM-1,beta-lactamase_156,P62593,0.989465,NO,202,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.292,-3.543,2.251,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.111618,0.00321899,0.989465 beta-lactamase_156_T147E,beta-lactamase_156_147,TEM-1,beta-lactamase_156,P62593,0.989465,NO,147,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.149,-3.519,2.37,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.111618,0.00226017,0.989465 beta-lactamase_2500_N152T,beta-lactamase_2500_152,TEM-1,beta-lactamase_2500,P62593,0.989471,NO,152,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-2.757,-2.377,-0.38,,0.863,H,A,0.61,0.92,2.061,,77.62,BPH,-2.97,0.361275,0.00471429,0.989471 beta-lactamase_39_A247R,beta-lactamase_39_247,TEM-1,beta-lactamase_39,P62593,0.98948,NO,247,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.0495842,0.00611275,0.98948 beta-lactamase_T267K,beta-lactamase_267,TEM-1,beta-lactamase,P62593,0.98948,NO,267,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.308,-3.523,1.215,5.28263,0.54,,B,0.69,-0.14,0.374,,73.78,HPH,-1.9,0.221079,0.0102128,0.98948 beta-lactamase_39_A182W,beta-lactamase_39_182,TEM-1,beta-lactamase_39,P62593,0.989481,NO,182,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.777,-5.53,3.753,,0.136,H,A,0.46,-0.66,2.598,,93.01,OHH,-1.27367,0.0495842,0.00559099,0.989481 beta-lactamase_39_Q86H,beta-lactamase_39_86,TEM-1,beta-lactamase_39,P62593,0.989485,NO,86,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.4,-4.718,2.318,,0.696,S,A,0.64,2.38,27.704,27.704,77.62,OPA,-1.61067,0.0495842,0.00450027,0.989485 beta-lactamase_39_R242L,beta-lactamase_39_242,TEM-1,beta-lactamase_39,P62593,0.989491,NO,242,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.0495842,0.00452879,0.989491 beta-lactamase_625_E279R,beta-lactamase_625_279,TEM-1,beta-lactamase_625,P62593,0.989507,NO,279,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.213352,0.0192826,0.989507 beta-lactamase_625_L111H,beta-lactamase_625_111,TEM-1,beta-lactamase_625,P62593,0.98951,NO,111,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.76,-4.922,3.162,,0.328,T,A,0.55,0.93,2.26,,64.34,BHP,-1.884,0.213352,0.00480671,0.98951 beta-lactamase_625_R92H,beta-lactamase_625_92,TEM-1,beta-lactamase_625,P62593,0.989512,NO,92,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.718,-4.618,2.9,,0.479,E,B,1.2,1.36,3.069,,65.38,BBH,-1.50367,0.213352,0.00429626,0.989512 beta-lactamase_156_L160V,beta-lactamase_156_160,TEM-1,beta-lactamase_156,P62593,0.989517,NO,160,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.977,-2.271,1.294,,0.022,,B,0.55,-0.6,1.095,,44.41,BHA,-0.936,0.111618,0.00193775,0.989517 beta-lactamase_A9F,beta-lactamase_9,TEM-1,beta-lactamase,P62593,0.989517,NO,9,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.147,-3.944,1.797,,,,,,,5.128,,72.73,HHH,-2.04267,0.221079,0.00247263,0.989517 beta-lactamase_V42V,beta-lactamase_42,TEM-1,beta-lactamase,P62593,0.989517,NO,42,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.564,-1.564,,5.27904,0.017,E,B,1.64,-0.51,2.024,,63.99,BHO,-1.042,0.221079,0.00404515,0.989517 beta-lactamase_625_T269W,beta-lactamase_625_269,TEM-1,beta-lactamase_625,P62593,0.989518,NO,269,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.213352,0.00950944,0.989518 Pab1_P135D,Pab1_135,Pab1,Pab1,P04147,0.989526,NO,135,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.457,-3.404,1.947,,,,,,,6.41,,81.8,BOA,-1.53367,0.175299,0.00148028,0.989526 beta-lactamase_625_W163K,beta-lactamase_625_163,TEM-1,beta-lactamase_625,P62593,0.989533,NO,163,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-1.843,-2.971,1.128,,0.467,,B,0.47,-0.5,5.019,,63.99,BHA,-1.269,0.213352,0.00418955,0.989533 beta-lactamase_2500_A222Q,beta-lactamase_2500_222,TEM-1,beta-lactamase_2500,P62593,0.989534,NO,222,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.103,-4.105,2.002,,0.233,H,A,0.46,-0.25,0.379,,77.62,PHH,-1.63733,0.361275,0.00466094,0.989534 beta-lactamase_39_V260M,beta-lactamase_39_260,TEM-1,beta-lactamase_39,P62593,0.989534,NO,260,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.0495842,0.00471757,0.989534 beta-lactamase_39_L89R,beta-lactamase_39_89,TEM-1,beta-lactamase_39,P62593,0.989535,NO,89,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.096,-3.963,2.867,,0.168,T,A,0.55,0.63,3.233,,64.34,PHO,-1.75767,0.0495842,0.00207068,0.989535 beta-lactamase_625_L199R,beta-lactamase_625_199,TEM-1,beta-lactamase_625,P62593,0.989541,NO,199,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-2.942,-3.181,0.239,,0.832,H,A,0.55,0.42,1.552,,77.62,PHH,-2.32933,0.213352,0.0048649,0.989541 beta-lactamase_39_L197W,beta-lactamase_39_197,TEM-1,beta-lactamase_39,P62593,0.989546,NO,197,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.853,-5.146,4.293,,0.007,S,B,0.55,0.33,1.559,,60.14,HHP,-1.833,0.0495842,0.00144602,0.989546 beta-lactamase_39_E61I,beta-lactamase_39_61,TEM-1,beta-lactamase_39,P62593,0.989553,NO,61,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.115,-4.14,2.025,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.0495842,0.00440955,0.989553 beta-lactamase_156_G39K,beta-lactamase_156_39,TEM-1,beta-lactamase_156,P62593,0.989563,NO,39,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.864,-2.703,0.839,,0.701,T,L,0.29,0.47,1.454,,77.62,HOH,-1.53633,0.111618,0.00487611,0.989563 beta-lactamase_156_H287V,beta-lactamase_156_287,TEM-1,beta-lactamase_156,P62593,0.989563,NO,287,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,,,,,,,,,,,,,BBH,-1.111,0.111618,,0.989563 beta-lactamase_39_N98T,beta-lactamase_39_98,TEM-1,beta-lactamase_39,P62593,0.989567,NO,98,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-2.973,-2.907,-0.066,,0.963,G,A,0.61,1.35,14.853,14.853,77.62,PPA,-2.07867,0.0495842,0.00505389,0.989567 beta-lactamase_39_T193L,beta-lactamase_39_193,TEM-1,beta-lactamase_39,P62593,0.989567,NO,193,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.914,-1.776,-0.138,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.0495842,0.00482669,0.989567 beta-lactamase_625_D99N,beta-lactamase_625_99,TEM-1,beta-lactamase_625,P62593,0.989575,NO,99,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.191,-3.466,2.275,,0.402,G,A,0.75,0.36,1.318,,64.69,PAH,-1.794,0.213352,0.00305446,0.989575 beta-lactamase_39_G253D,beta-lactamase_39_253,TEM-1,beta-lactamase_39,P62593,0.989584,NO,253,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.0495842,0.00786358,0.989584 beta-lactamase_39_G76H,beta-lactamase_39_76,TEM-1,beta-lactamase_39,P62593,0.989586,NO,76,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.189,-4.754,3.565,,,H,A,0.29,-0.67,2.145,,67.83,OOH,-1.22267,0.0495842,0.00476637,0.989586 beta-lactamase_156_A182M,beta-lactamase_156_182,TEM-1,beta-lactamase_156,P62593,0.989587,NO,182,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.777,-4.709,2.932,,0.136,H,A,0.46,-0.66,16.784,16.784,93.01,OHH,-1.27367,0.111618,0.00559099,0.989587 beta-lactamase_156_P172Y,beta-lactamase_156_172,TEM-1,beta-lactamase_156,P62593,0.989589,NO,172,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.998,-4.368,3.37,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.111618,0.00312594,0.989589 beta-lactamase_39_L135W,beta-lactamase_39_135,TEM-1,beta-lactamase_39,P62593,0.98959,NO,135,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.002,-5.166,4.164,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.0495842,0.00244423,0.98959 beta-lactamase_156_H24C,beta-lactamase_156_24,TEM-1,beta-lactamase_156,P62593,0.989597,NO,24,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-2.481,-4.897,2.416,,,,,,,2.708,,93.01,OBO,-2.0035,0.111618,0.00238894,0.989597 beta-lactamase_156_D207H,beta-lactamase_156_207,TEM-1,beta-lactamase_156,P62593,0.9896,NO,207,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.064,-3.07,1.006,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.111618,0.00592942,0.9896 beta-lactamase_39_L111S,beta-lactamase_39_111,TEM-1,beta-lactamase_39,P62593,0.989606,NO,111,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.76,-3.564,1.804,,0.328,T,A,0.55,0.93,4.334,,64.34,BHP,-1.884,0.0495842,0.00480671,0.989606 beta-lactamase_625_T116R,beta-lactamase_625_116,TEM-1,beta-lactamase_625,P62593,0.989606,NO,116,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.28,-2.627,1.347,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.213352,0.00336175,0.989606 beta-lactamase_625_V260G,beta-lactamase_625_260,TEM-1,beta-lactamase_625,P62593,0.989608,NO,260,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.213352,0.00471757,0.989608 beta-lactamase_39_L137M,beta-lactamase_39_137,TEM-1,beta-lactamase_39,P62593,0.989611,NO,137,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.03,-2.58,1.55,,,H,A,0.55,-0.38,0.674,,42.31,HHP,-1.58933,0.0495842,0.00278599,0.989611 beta-lactamase_625_E102V,beta-lactamase_625_102,TEM-1,beta-lactamase_625,P62593,0.989611,NO,102,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.118,-3.638,1.52,,0.722,S,B,1.04,1.82,1.336,,73.08,HAH,-1.581,0.213352,0.00486633,0.989611 beta-lactamase_39_N134L,beta-lactamase_39_134,TEM-1,beta-lactamase_39,P62593,0.989613,NO,134,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-0.879,-3.581,2.702,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.0495842,0.000644786,0.989613 beta-lactamase_2500_Q276I,beta-lactamase_2500_276,TEM-1,beta-lactamase_2500,P62593,0.989621,NO,276,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.361275,0.0191712,0.989621 beta-lactamase_156_I171F,beta-lactamase_156_171,TEM-1,beta-lactamase_156,P62593,0.989627,NO,171,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-2.431,-3.175,0.744,,0.361,,B,0.48,0.53,3.869,,77.62,HHO,-1.55533,0.111618,0.00623355,0.989627 beta-lactamase_2500_E61T,beta-lactamase_2500_61,TEM-1,beta-lactamase_2500,P62593,0.989627,NO,61,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.115,-3.52,1.405,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.361275,0.00440955,0.989627 beta-lactamase_625_P172R,beta-lactamase_625_172,TEM-1,beta-lactamase_625,P62593,0.989632,NO,172,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.998,-3.96,2.962,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.213352,0.00312594,0.989632 beta-lactamase_625_V101L,beta-lactamase_625_101,TEM-1,beta-lactamase_625,P62593,0.989633,NO,101,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.295,-2.095,0.8,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.213352,0.00374492,0.989633 beta-lactamase_39_K53T,beta-lactamase_39_53,TEM-1,beta-lactamase_39,P62593,0.989634,NO,53,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-2.313,-2.702,0.389,,0.589,,B,2.34,1.15,15.633,15.633,77.62,OBH,-2.1,0.0495842,0.00383383,0.989634 beta-lactamase_625_A170G,beta-lactamase_625_170,TEM-1,beta-lactamase_625,P62593,0.989636,NO,170,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.237,-1.884,0.647,,0.126,,L,0.46,-0.35,3.626,,64.69,AHH,-1.63267,0.213352,0.00431903,0.989636 PSD95pdz3_S371T,PSD95pdz3_371,PSD95pdz3,PSD95pdz3,P31016,0.989637,NO,371,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.86,-1.533,-0.327,5.19744,,,,,17.1117,3.854,,87.71,HPB,-1.598,0.0758425,0.000847873,0.989637 beta-lactamase_2500_K109V,beta-lactamase_2500_109,TEM-1,beta-lactamase_2500,P62593,0.989638,NO,109,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.734,-3.727,1.993,,0.787,G,A,2.34,2.21,0.998,,72.73,ABB,-1.63333,0.361275,0.00462493,0.989638 beta-lactamase_156_I54S,beta-lactamase_156_54,TEM-1,beta-lactamase_156,P62593,0.989644,NO,54,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-2.838,-3.459,0.621,,0.669,E,B,0.48,-0.14,0.541,,73.78,BHH,-2.337,0.111618,0.00403589,0.989644 beta-lactamase_156_P143V,beta-lactamase_156_143,TEM-1,beta-lactamase_156,P62593,0.989646,NO,143,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.967,-3.311,2.344,,0.075,H,A,0.52,-0.37,0.479,,66.78,OOB,-1.354,0.111618,0.00114551,0.989646 beta-lactamase_39_L192A,beta-lactamase_39_192,TEM-1,beta-lactamase_39,P62593,0.989647,NO,192,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.254,-2.317,1.063,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.0495842,0.00558728,0.989647 beta-lactamase_156_R176S,beta-lactamase_156_176,TEM-1,beta-lactamase_156,P62593,0.989652,NO,176,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-0.863,-3.386,2.523,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.111618,0.00105554,0.989652 kka2_1:8_G245A,kka2_1:8_245,Kka2,kka2_1:8,P00552,0.989653,NO,245,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.812,-2.418,1.606,,0.655,T,g,0.75,0.03,1.148,,65.53,HOH,-1.19833,0.100394,0.00683899,0.989653 kka2_1:8_G245A,kka2_1:8_245,Kka2,kka2_1:8,P00552,0.989653,NO,245,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.812,-2.418,1.606,,0.655,T,g,0.75,0.03,1.148,,65.53,HOH,-1.19833,0.100394,0.00683899,0.989653 beta-lactamase_2500_L167I,beta-lactamase_2500_167,TEM-1,beta-lactamase_2500,P62593,0.989654,NO,167,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.138,-3.085,1.947,,0.015,G,A,0.55,-0.63,7.813,,64.69,AHP,-1.30767,0.361275,0.00303566,0.989654 beta-lactamase_D269T,beta-lactamase_269,TEM-1,beta-lactamase,P62593,0.989657,NO,269,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.156,-3.518,1.362,5.47645,0.646,H,A,0.23,0.4,21.796,21.796,77.62,HAA,-1.96733,0.221079,0.00950944,0.989657 beta-lactamase_H110K,beta-lactamase_110,TEM-1,beta-lactamase,P62593,0.989657,NO,110,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-1.706,-2.755,1.049,5.52635,0.341,G,a,0.35,1.08,31.31,31.31,64.69,BBH,-1.73333,0.221079,0.00441499,0.989657 beta-lactamase_625_A225L,beta-lactamase_625_225,TEM-1,beta-lactamase_625,P62593,0.989671,NO,225,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.845,-2.985,1.14,,1,T,B,0.46,-0.38,9.874,9.874,74.48,OHO,-1.39967,0.213352,0.00465057,0.989671 beta-lactamase_39_L199T,beta-lactamase_39_199,TEM-1,beta-lactamase_39,P62593,0.989681,NO,199,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-2.942,-2.763,-0.179,,0.832,H,A,0.55,0.42,15.504,15.504,77.62,PHH,-2.32933,0.0495842,0.0048649,0.989681 beta-lactamase_625_I171G,beta-lactamase_625_171,TEM-1,beta-lactamase_625,P62593,0.989687,NO,171,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-2.431,-3.603,1.172,,0.361,,B,0.48,0.53,3.869,,77.62,HHO,-1.55533,0.213352,0.00623355,0.989687 beta-lactamase_156_L38A,beta-lactamase_156_38,TEM-1,beta-lactamase_156,P62593,0.98969,NO,38,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.343,-3.151,1.808,,0.088,H,A,0.55,0.2,13.556,13.556,64.34,PHO,-1.78033,0.111618,0.00373244,0.98969 beta-lactamase_156_V101A,beta-lactamase_156_101,TEM-1,beta-lactamase_156,P62593,0.98969,NO,101,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.295,-3.114,1.819,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.111618,0.00374492,0.98969 beta-lactamase_625_G90R,beta-lactamase_625_90,TEM-1,beta-lactamase_625,P62593,0.98969,NO,90,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-2.091,-3.098,1.007,,0.598,T,A,0.29,0.32,0.319,,77.62,HOB,-1.52633,0.213352,0.00490273,0.98969 kka2_1:4_L47T,kka2_1:4_47,Kka2,kka2_1:4,P00552,0.989692,NO,47,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.265,-3.56,2.295,,0.139,E,B,0.55,-0.86,2.369,,63.26,HHH,-1.77933,0.168804,0.00509386,0.989692 beta-lactamase_625_Q267D,beta-lactamase_625_267,TEM-1,beta-lactamase_625,P62593,0.989697,NO,267,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.213352,0.0102128,0.989697 beta-lactamase_625_N130C,beta-lactamase_625_130,TEM-1,beta-lactamase_625,P62593,0.9897,NO,130,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-0.798,-5.087,4.289,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.213352,0.000683376,0.9897 gb1_N234S,gb1_234,gb1,gb1,P06654,0.989701,NO,234,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-2.055,-2.986,0.931,,,,,,,1.235,,45.54,HPO,-2.05067,0.177985,0.00242189,0.989701 gb1_T243M,gb1_243,gb1,gb1,P06654,0.989701,NO,243,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.415,-4.291,2.876,,,,,,,1.083,,37.28,PPP,-1.43233,0.177985,0.00308687,0.989701 beta-lactamase_2500_V157Q,beta-lactamase_2500_157,TEM-1,beta-lactamase_2500,P62593,0.989703,NO,157,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.751,-4.045,2.294,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.361275,0.00506849,0.989703 beta-lactamase_156_T116G,beta-lactamase_156_116,TEM-1,beta-lactamase_156,P62593,0.989705,NO,116,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.28,-3.287,2.007,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.111618,0.00336175,0.989705 beta-lactamase_2500_D113H,beta-lactamase_2500_113,TEM-1,beta-lactamase_2500,P62593,0.989713,NO,113,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.829,-4.704,2.875,,0.665,T,A,0.75,0.91,21.104,21.104,73.08,PAO,-1.703,0.361275,0.00474112,0.989713 beta-lactamase_625_Q204K,beta-lactamase_625_204,TEM-1,beta-lactamase_625,P62593,0.989715,NO,204,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-1.382,-2.218,0.836,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.213352,0.00364106,0.989715 beta-lactamase_156_Q276D,beta-lactamase_156_276,TEM-1,beta-lactamase_156,P62593,0.989717,NO,276,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.111618,0.0191712,0.989717 beta-lactamase_0_S68R,beta-lactamase_0_68,TEM-1,beta-lactamase_0,P62593,0.989719,NO,68,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-0.913,-3.705,2.792,,0.064,G,A,0.27,-1.03,1.441,,64.69,HPP,-1.37233,0.0500837,0.000800065,0.989719 Pab1_D144V,Pab1_144,Pab1,Pab1,P04147,0.989726,NO,144,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.189,-3.567,2.378,,0.616,H,A,,0.6,,,,HAP,-1.40567,0.175299,0.00121131,0.989726 beta-lactamase_2500_R275L,beta-lactamase_2500_275,TEM-1,beta-lactamase_2500,P62593,0.989729,NO,275,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.361275,0.0141984,0.989729 beta-lactamase_156_E238F,beta-lactamase_156_238,TEM-1,beta-lactamase_156,P62593,0.98973,NO,238,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.111618,0.00743256,0.98973 beta-lactamase_S57R,beta-lactamase_57,TEM-1,beta-lactamase,P62593,0.989734,NO,57,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.918,-3.069,1.151,5.64201,0.352,E,B,0.25,-0.18,1.971,,72.73,APH,-2.29167,0.221079,0.00492804,0.989734 beta-lactamase_39_L136T,beta-lactamase_39_136,TEM-1,beta-lactamase_39,P62593,0.989739,NO,136,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.232,-3.487,2.255,,,H,A,0.55,-0.34,0.336,,48.95,HHH,-1.088,0.0495842,0.00442304,0.989739 beta-lactamase_625_A200E,beta-lactamase_625_200,TEM-1,beta-lactamase_625,P62593,0.989742,NO,200,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.878,-2.662,0.784,,0.757,H,A,0.46,-0.19,12.672,12.672,77.62,HHP,-2.001,0.213352,0.0060056,0.989742 beta-lactamase_156_V259A,beta-lactamase_156_259,TEM-1,beta-lactamase_156,P62593,0.989747,NO,259,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.111618,0.0070773,0.989747 beta-lactamase_W163I,beta-lactamase_163,TEM-1,beta-lactamase,P62593,0.989752,NO,163,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-1.843,-3.136,1.293,6.2765,0.467,,B,1.22,-0.5,3.642,,63.99,BHA,-1.269,0.221079,0.00418955,0.989752 beta-lactamase_625_R176Q,beta-lactamase_625_176,TEM-1,beta-lactamase_625,P62593,0.989754,NO,176,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-0.863,-3.449,2.586,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.213352,0.00105554,0.989754 beta-lactamase_0_S233A,beta-lactamase_0_233,TEM-1,beta-lactamase_0,P62593,0.989755,NO,233,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.886,-2.424,0.538,,0.016,E,B,0.27,-1.01,3.579,,77.62,BPO,-1.17267,0.0500837,0.00311415,0.989755 beta-lactamase_39_E61A,beta-lactamase_39_61,TEM-1,beta-lactamase_39,P62593,0.98976,NO,61,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.115,-2.668,0.553,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.0495842,0.00440955,0.98976 beta-lactamase_39_A182M,beta-lactamase_39_182,TEM-1,beta-lactamase_39,P62593,0.989768,NO,182,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.777,-4.709,2.932,,0.136,H,A,0.46,-0.66,2.598,,93.01,OHH,-1.27367,0.0495842,0.00559099,0.989768 beta-lactamase_156_S122C,beta-lactamase_156_122,TEM-1,beta-lactamase_156,P62593,0.989772,NO,122,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.406,-5.091,2.685,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.111618,0.00497825,0.989772 beta-lactamase_156_M153C,beta-lactamase_156_153,TEM-1,beta-lactamase_156,P62593,0.989773,NO,153,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-3.193,-4.79,1.597,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.111618,0.00509109,0.989773 beta-lactamase_625_P172V,beta-lactamase_625_172,TEM-1,beta-lactamase_625,P62593,0.989773,NO,172,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.998,-3.483,2.485,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.213352,0.00312594,0.989773 beta-lactamase_H110H,beta-lactamase_110,TEM-1,beta-lactamase,P62593,0.989774,NO,110,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-1.706,-1.706,,5.52635,0.341,G,a,0.35,1.08,31.31,31.31,64.69,BBH,-1.73333,0.221079,0.00441499,0.989774 beta-lactamase_2500_H151W,beta-lactamase_2500_151,TEM-1,beta-lactamase_2500,P62593,0.989781,NO,151,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-2.96,-5.334,2.374,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.361275,0.00216946,0.989781 beta-lactamase_39_K286M,beta-lactamase_39_286,TEM-1,beta-lactamase_39,P62593,0.989784,NO,286,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.0495842,,0.989784 beta-lactamase_625_K232R,beta-lactamase_625_232,TEM-1,beta-lactamase_625,P62593,0.989784,NO,232,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.012,-1.888,0.876,,,E,B,2.34,-1.1,1.992,,65.03,ABP,-1.238,0.213352,0.00313441,0.989784 beta-lactamase_H5Y,beta-lactamase_5,TEM-1,beta-lactamase,P62593,0.989789,NO,5,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-2.698,-2.15,-0.548,,,,,,,1.865,,72.73,PBH,-2.36967,0.221079,0.00292712,0.989789 beta-lactamase_I125L,beta-lactamase_125,TEM-1,beta-lactamase,P62593,0.989789,NO,125,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.441,-1.939,0.498,5.23481,,H,A,2.82,-0.7,2.301,,63.29,HHP,-1.248,0.221079,0.00383964,0.989789 beta-lactamase_39_E166V,beta-lactamase_39_166,TEM-1,beta-lactamase_39,P62593,0.989791,NO,166,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.756,-2.896,1.14,,0.508,G,A,1.04,1.05,17.227,17.227,73.08,OAH,-1.42233,0.0495842,0.00512989,0.989791 beta-lactamase_156_G154A,beta-lactamase_156_154,TEM-1,beta-lactamase_156,P62593,0.989799,NO,154,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.823,-2.356,1.533,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.111618,0.00180205,0.989799 beta-lactamase_625_H156Q,beta-lactamase_625_156,TEM-1,beta-lactamase_625,P62593,0.989799,NO,156,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-3.156,-2.776,-0.38,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.213352,0.00468596,0.989799 beta-lactamase_625_Y95L,beta-lactamase_625_95,TEM-1,beta-lactamase_625,P62593,0.989799,NO,95,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-1.715,-2.545,0.83,,0.122,,b,0.21,-0.37,3.355,,77.62,BHP,-2.16167,0.213352,0.00479449,0.989799 beta-lactamase_2500_T269H,beta-lactamase_2500_269,TEM-1,beta-lactamase_2500,P62593,0.989802,NO,269,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.361275,0.00950944,0.989802 beta-lactamase_156_T269W,beta-lactamase_156_269,TEM-1,beta-lactamase_156,P62593,0.989803,NO,269,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.111618,0.00950944,0.989803 beta-lactamase_39_G52P,beta-lactamase_39_52,TEM-1,beta-lactamase_39,P62593,0.989805,NO,52,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.149,-2.849,1.7,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.0495842,0.00340138,0.989805 beta-lactamase_156_L197S,beta-lactamase_156_197,TEM-1,beta-lactamase_156,P62593,0.989806,NO,197,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.853,-3.532,2.679,,0.007,S,B,0.55,0.33,1.58,,60.14,HHP,-1.833,0.111618,0.00144602,0.989806 beta-lactamase_625_G52D,beta-lactamase_625_52,TEM-1,beta-lactamase_625,P62593,0.989806,NO,52,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.149,-2.123,0.974,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.213352,0.00340138,0.989806 beta-lactamase_39_M127C,beta-lactamase_39_127,TEM-1,beta-lactamase_39,P62593,0.989814,NO,127,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-2.251,-5.009,2.758,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.0495842,0.00437927,0.989814 beta-lactamase_156_G52E,beta-lactamase_156_52,TEM-1,beta-lactamase_156,P62593,0.989815,NO,52,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.149,-3.424,2.275,,0.299,,l,0.29,-0.04,1.179,,64.69,POB,-1.66267,0.111618,0.00340138,0.989815 beta-lactamase_A235A,beta-lactamase_235,TEM-1,beta-lactamase,P62593,0.989815,NO,235,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.266,-1.266,,4.83024,0.32,E,B,0.52,-0.86,1.344,,50,OHO,-0.89,0.221079,0.00493474,0.989815 beta-lactamase_39_I45Q,beta-lactamase_39_45,TEM-1,beta-lactamase_39,P62593,0.989816,NO,45,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-2.421,-3.24,0.819,,,E,B,0.48,-0.3,2.256,,77.62,HHA,-2.30267,0.0495842,0.00452842,0.989816 beta-lactamase_S122G,beta-lactamase_122,TEM-1,beta-lactamase,P62593,0.98982,NO,122,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.406,-3.475,1.069,4.87767,0.352,H,A,0.73,-0.54,1.581,,77.62,OPH,-1.39767,0.221079,0.00497825,0.98982 beta-lactamase_39_L191S,beta-lactamase_39_191,TEM-1,beta-lactamase_39,P62593,0.989828,NO,191,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.087,-3.562,2.475,,,H,A,0.55,0.09,1.372,,63.29,BHH,-1.445,0.0495842,0.00263549,0.989828 beta-lactamase_2500_E145K,beta-lactamase_2500_145,TEM-1,beta-lactamase_2500,P62593,0.989829,NO,145,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.357,-3.472,1.115,,0.545,H,A,1.04,0.79,2.124,,77.62,BAH,-2.069,0.361275,0.00553285,0.989829 beta-lactamase_0_G216A,beta-lactamase_0_216,TEM-1,beta-lactamase_0,P62593,0.989832,NO,216,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.477,-2.596,1.119,,0.437,I,A,0.29,-0.58,0.834,,74.48,HOO,-1.68067,0.0500837,0.00639568,0.989832 beta-lactamase_39_A278E,beta-lactamase_39_278,TEM-1,beta-lactamase_39,P62593,0.989834,NO,278,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.0495842,0.0310297,0.989834 beta-lactamase_625_P143A,beta-lactamase_625_143,TEM-1,beta-lactamase_625,P62593,0.989835,NO,143,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.967,-3.126,2.159,,0.075,H,A,0.52,-0.37,1.445,,66.78,OOB,-1.354,0.213352,0.00114551,0.989835 beta-lactamase_625_E62G,beta-lactamase_625_62,TEM-1,beta-lactamase_625,P62593,0.989838,NO,62,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.193,-2.548,1.355,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.213352,0.00264802,0.989838 beta-lactamase_39_S283H,beta-lactamase_39_283,TEM-1,beta-lactamase_39,P62593,0.989847,NO,283,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.0495842,0.0429138,0.989847 kka2_1:8_A191S,kka2_1:8_191,Kka2,kka2_1:8,P00552,0.989857,NO,191,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.831,-3.052,2.221,,,,b,1.04,-0.94,1.306,,50,AHO,-0.868667,0.100394,0.00338807,0.989857 kka2_1:8_A191S,kka2_1:8_191,Kka2,kka2_1:8,P00552,0.989857,NO,191,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.831,-3.052,2.221,,,,b,1.04,-0.94,1.306,,50,AHO,-0.868667,0.100394,0.00338807,0.989857 WW_domain_I193I,WW_domain_193,Yap65,WW_domain,P46937,0.989857,NO,193,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.993,-1.993,0,6.15906,,,,,,1.833,,83.33,BHA,-1.756,0.153962,0.00587613,0.989857 beta-lactamase_39_S241N,beta-lactamase_39_241,TEM-1,beta-lactamase_39,P62593,0.989859,NO,241,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.0495842,0.00452736,0.989859 beta-lactamase_39_K32S,beta-lactamase_39_32,TEM-1,beta-lactamase_39,P62593,0.989862,NO,32,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.984,-3.371,1.387,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.0495842,0.00401283,0.989862 beta-lactamase_625_D207G,beta-lactamase_625_207,TEM-1,beta-lactamase_625,P62593,0.989865,NO,207,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.064,-2.283,0.219,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.213352,0.00592942,0.989865 beta-lactamase_625_Q86E,beta-lactamase_625_86,TEM-1,beta-lactamase_625,P62593,0.989866,NO,86,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.4,-2.379,-0.021,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.213352,0.00450027,0.989866 beta-lactamase_156_D231T,beta-lactamase_156_231,TEM-1,beta-lactamase_156,P62593,0.989868,NO,231,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.816,-3.447,2.631,,,E,B,0.75,-1.06,2.66,,65.38,HAB,-0.994,0.111618,0.00107395,0.989868 beta-lactamase_156_L111N,beta-lactamase_156_111,TEM-1,beta-lactamase_156,P62593,0.989868,NO,111,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.76,-4.132,2.372,,0.328,T,A,0.55,0.93,2.26,,64.34,BHP,-1.884,0.111618,0.00480671,0.989868 beta-lactamase_Q88W,beta-lactamase_88,TEM-1,beta-lactamase,P62593,0.989872,NO,88,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.086,-5.502,3.416,5.8056,0.807,,B,0.12,2.03,1.84,,77.62,APH,-1.53433,0.221079,0.00504167,0.989872 beta-lactamase_S122H,beta-lactamase_122,TEM-1,beta-lactamase,P62593,0.989872,NO,122,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.406,-2.676,0.27,4.87767,0.352,H,A,0.73,-0.54,1.581,,77.62,OPH,-1.39767,0.221079,0.00497825,0.989872 beta-lactamase_S80W,beta-lactamase_80,TEM-1,beta-lactamase,P62593,0.989872,NO,80,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.029,-5.529,3.5,5.23748,0.192,H,A,0.25,0.46,2.256,,77.62,HPB,-1.44567,0.221079,0.00565569,0.989872 beta-lactamase_V157I,beta-lactamase_157,TEM-1,beta-lactamase,P62593,0.989872,NO,157,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.751,-2.621,0.87,5.51733,0.308,S,a,0.96,-0.75,1.847,,69.58,BHP,-2.00767,0.221079,0.00506849,0.989872 beta-lactamase_V29T,beta-lactamase_29,TEM-1,beta-lactamase,P62593,0.989872,NO,29,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-2.856,-2.552,-0.304,5.58481,0.733,H,A,0.23,-0.78,1.287,,93.01,HHB,-2.24733,0.221079,0.00318969,0.989872 beta-lactamase_39_S221H,beta-lactamase_39_221,TEM-1,beta-lactamase_39,P62593,0.989875,NO,221,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.754,-4.673,2.919,,0.624,H,A,0.27,-0.2,2.69,,74.48,BPH,-1.59967,0.0495842,0.0046094,0.989875 beta-lactamase_39_R81S,beta-lactamase_39_81,TEM-1,beta-lactamase_39,P62593,0.98988,NO,81,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.466,-3.386,1.92,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.0495842,0.00499763,0.98988 beta-lactamase_156_Q203Y,beta-lactamase_156_203,TEM-1,beta-lactamase_156,P62593,0.989885,NO,203,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.168,-4.35,2.182,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.111618,0.00631514,0.989885 beta-lactamase_39_S57T,beta-lactamase_39_57,TEM-1,beta-lactamase_39,P62593,0.989889,NO,57,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.918,-2.297,0.379,,0.352,E,B,0.27,-0.18,2.3,,72.73,APH,-2.29167,0.0495842,0.00492804,0.989889 beta-lactamase_2500_L199W,beta-lactamase_2500_199,TEM-1,beta-lactamase_2500,P62593,0.98989,NO,199,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-2.942,-5.582,2.64,,0.832,H,A,0.55,0.42,15.504,15.504,77.62,PHH,-2.32933,0.361275,0.0048649,0.98989 beta-lactamase_625_I206L,beta-lactamase_625_206,TEM-1,beta-lactamase_625,P62593,0.989895,NO,206,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-2.429,-2.261,-0.168,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.213352,0.00528934,0.989895 Pab1_D144H,Pab1_144,Pab1,Pab1,P04147,0.989897,NO,144,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.189,-4.269,3.08,,0.616,H,A,,0.6,,,,HAP,-1.40567,0.175299,0.00121131,0.989897 beta-lactamase_625_S96W,beta-lactamase_625_96,TEM-1,beta-lactamase_625,P62593,0.989901,NO,96,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.27,-5.497,3.227,,0.368,,b,0.27,0.39,5.244,,73.78,HPP,-2.019,0.213352,0.00551835,0.989901 beta-lactamase_156_G90Q,beta-lactamase_156_90,TEM-1,beta-lactamase_156,P62593,0.989903,NO,90,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-2.091,-2.862,0.771,,0.598,T,A,0.29,0.32,0.319,,77.62,HOB,-1.52633,0.111618,0.00490273,0.989903 beta-lactamase_156_A183E,beta-lactamase_156_183,TEM-1,beta-lactamase_156,P62593,0.98991,NO,183,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.231,-3.42,2.189,,0.155,H,A,0.46,-0.91,23.859,23.859,77.62,HHH,-1.53367,0.111618,0.00296631,0.98991 beta-lactamase_39_A278W,beta-lactamase_39_278,TEM-1,beta-lactamase_39,P62593,0.98991,NO,278,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.0495842,0.0310297,0.98991 beta-lactamase_156_L136M,beta-lactamase_156_136,TEM-1,beta-lactamase_156,P62593,0.989917,NO,136,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.232,-2.988,1.756,,,H,A,0.55,-0.34,1.04,,48.95,HHH,-1.088,0.111618,0.00442304,0.989917 beta-lactamase_625_V78A,beta-lactamase_625_78,TEM-1,beta-lactamase_625,P62593,0.989917,NO,78,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.459,-3.121,1.662,,,H,A,0.44,-0.47,2.045,,63.64,HHH,-1.17833,0.213352,0.00492501,0.989917 beta-lactamase_625_I171L,beta-lactamase_625_171,TEM-1,beta-lactamase_625,P62593,0.989923,NO,171,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-2.431,-1.98,-0.451,,0.361,,B,0.48,0.53,3.869,,77.62,HHO,-1.55533,0.213352,0.00623355,0.989923 beta-lactamase_K252Y,beta-lactamase_252,TEM-1,beta-lactamase,P62593,0.989929,NO,252,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.94,-4.256,2.316,5.56823,0.766,,B,1.82,1.16,21.796,21.796,67.83,OBO,-2.03333,0.221079,0.00575769,0.989929 beta-lactamase_625_A278T,beta-lactamase_625_278,TEM-1,beta-lactamase_625,P62593,0.989931,NO,278,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.213352,0.0310297,0.989931 beta-lactamase_39_E175S,beta-lactamase_39_175,TEM-1,beta-lactamase_39,P62593,0.989932,NO,175,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.336,-2.863,0.527,,0.551,,A,1.04,1.05,3.676,,77.62,AAB,-1.31233,0.0495842,0.00482205,0.989932 beta-lactamase_156_L28C,beta-lactamase_156_28,TEM-1,beta-lactamase_156,P62593,0.989939,NO,28,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.579,-4.763,3.184,,0.277,H,A,0.55,-0.16,3.262,,93.01,PHH,-2.11333,0.111618,0.00359321,0.989939 beta-lactamase_625_G85S,beta-lactamase_625_85,TEM-1,beta-lactamase_625,P62593,0.989942,NO,85,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.011,-3.264,2.253,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.213352,0.00252173,0.989942 beta-lactamase_625_L160I,beta-lactamase_625_160,TEM-1,beta-lactamase_625,P62593,0.989942,NO,160,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.977,-2.155,1.178,,0.022,,B,0.55,-0.6,0.237,,44.41,BHA,-0.936,0.213352,0.00193775,0.989942 beta-lactamase_156_A185G,beta-lactamase_156_185,TEM-1,beta-lactamase_156,P62593,0.989951,NO,185,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.406,-3.37,1.964,,,H,A,0.46,-1.02,0.365,,65.03,HHP,-1.84033,0.111618,0.00467449,0.989951 beta-lactamase_625_V82K,beta-lactamase_625_82,TEM-1,beta-lactamase_625,P62593,0.989951,NO,82,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.325,-3.754,2.429,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.213352,0.00397046,0.989951 beta-lactamase_625_L55M,beta-lactamase_625_55,TEM-1,beta-lactamase_625,P62593,0.989959,NO,55,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.86,-4.329,2.469,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.213352,0.00403741,0.989959 beta-lactamase_39_A282N,beta-lactamase_39_282,TEM-1,beta-lactamase_39,P62593,0.989961,NO,282,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.0495842,0.0449821,0.989961 beta-lactamase_L79L,beta-lactamase_79,TEM-1,beta-lactamase,P62593,0.989963,NO,79,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.842,-0.842,,4.98681,0.007,H,A,1.07,-0.16,0.823,,50.35,HHP,-1.44333,0.221079,0.000947397,0.989963 beta-lactamase_39_L192G,beta-lactamase_39_192,TEM-1,beta-lactamase_39,P62593,0.989967,NO,192,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.254,-3.698,2.444,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.0495842,0.00558728,0.989967 beta-lactamase_39_L89F,beta-lactamase_39_89,TEM-1,beta-lactamase_39,P62593,0.989968,NO,89,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.096,-3.844,2.748,,0.168,T,A,0.55,0.63,3.233,,64.34,PHO,-1.75767,0.0495842,0.00207068,0.989968 beta-lactamase_I275F,beta-lactamase_275,TEM-1,beta-lactamase,P62593,0.989971,NO,275,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.397,-2.867,1.47,5.3999,0.015,H,A,1,-0.52,0.836,,62.59,PHH,-1.541,0.221079,0.0141984,0.989971 beta-lactamase_625_G90P,beta-lactamase_625_90,TEM-1,beta-lactamase_625,P62593,0.989979,NO,90,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-2.091,-3.952,1.861,,0.598,T,A,0.29,0.32,0.319,,77.62,HOB,-1.52633,0.213352,0.00490273,0.989979 beta-lactamase_39_M115I,beta-lactamase_39_115,TEM-1,beta-lactamase_39,P62593,0.989986,NO,115,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.389,-3.258,1.869,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.0495842,0.0034337,0.989986 kka2_1:8_L81N,kka2_1:8_81,Kka2,kka2_1:8,P00552,0.989986,NO,81,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.427,-4.237,2.81,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.100394,0.00805839,0.989986 kka2_1:8_L81N,kka2_1:8_81,Kka2,kka2_1:8,P00552,0.989986,NO,81,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.427,-4.237,2.81,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.100394,0.00805839,0.989986 beta-lactamase_2500_I171C,beta-lactamase_2500_171,TEM-1,beta-lactamase_2500,P62593,0.989988,NO,171,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-2.431,-4.938,2.507,,0.361,,B,0.48,0.53,1.66,,77.62,HHO,-1.55533,0.361275,0.00623355,0.989988 PSD95pdz3_K393G,PSD95pdz3_393,PSD95pdz3,PSD95pdz3,P31016,0.989989,NO,393,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.416,-3.04,1.624,5.42682,,,,,22.0122,,,,HBO,-1.4265,0.0758425,0.000879298,0.989989 beta-lactamase_156_V82L,beta-lactamase_156_82,TEM-1,beta-lactamase_156,P62593,0.98999,NO,82,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.325,-2.426,1.101,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.111618,0.00397046,0.98999 beta-lactamase_156_G39H,beta-lactamase_156_39,TEM-1,beta-lactamase_156,P62593,0.989992,NO,39,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.864,-3.359,1.495,,0.701,T,L,0.29,0.47,1.454,,77.62,HOH,-1.53633,0.111618,0.00487611,0.989992 beta-lactamase_625_S57Y,beta-lactamase_625_57,TEM-1,beta-lactamase_625,P62593,0.989997,NO,57,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.918,-4.294,2.376,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.213352,0.00492804,0.989997 Pab1_G177H,Pab1_177,Pab1,Pab1,P04147,0.989997,NO,177,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-2.24,-4.389,2.149,,,,,,,,,,AOH,-1.94067,0.175299,0.00170727,0.989997 beta-lactamase_156_V82S,beta-lactamase_156_82,TEM-1,beta-lactamase_156,P62593,0.989998,NO,82,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.325,-3.501,2.176,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.111618,0.00397046,0.989998 beta-lactamase_156_E102F,beta-lactamase_156_102,TEM-1,beta-lactamase_156,P62593,0.989999,NO,102,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.118,-4.365,2.247,,0.722,S,B,1.04,1.82,15.721,15.721,73.08,HAH,-1.581,0.111618,0.00486633,0.989999 beta-lactamase_625_L38T,beta-lactamase_625_38,TEM-1,beta-lactamase_625,P62593,0.990001,NO,38,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.343,-3.495,2.152,,0.088,H,A,0.55,0.2,1.986,,64.34,PHO,-1.78033,0.213352,0.00373244,0.990001 beta-lactamase_39_L146V,beta-lactamase_39_146,TEM-1,beta-lactamase_39,P62593,0.990004,NO,146,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.462,-1.839,0.377,,0.007,H,A,0.55,-0.56,1.953,,64.69,AHP,-1.656,0.0495842,0.00474542,0.990004 beta-lactamase_156_V157L,beta-lactamase_156_157,TEM-1,beta-lactamase_156,P62593,0.990008,NO,157,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.751,-3.066,1.315,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.111618,0.00506849,0.990008 beta-lactamase_625_T264A,beta-lactamase_625_264,TEM-1,beta-lactamase_625,P62593,0.99001,NO,264,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.213352,0.0119399,0.99001 beta-lactamase_625_G154A,beta-lactamase_625_154,TEM-1,beta-lactamase_625,P62593,0.990013,NO,154,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.823,-2.356,1.533,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.213352,0.00180205,0.990013 kka2_1:2_W24V,kka2_1:2_24,Kka2,kka2_1:2,P00552,0.990021,NO,24,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-1.779,-2.484,0.705,,0.477,E,B,1.51,-0.21,2.666,,56.06,AHH,-2.24467,0.295029,0.00631564,0.990021 beta-lactamase_2500_K53L,beta-lactamase_2500_53,TEM-1,beta-lactamase_2500,P62593,0.990027,NO,53,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-2.313,-2.678,0.365,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.361275,0.00383383,0.990027 beta-lactamase_625_D36I,beta-lactamase_625_36,TEM-1,beta-lactamase_625,P62593,0.990027,NO,36,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.732,-4.112,1.38,,0.555,H,A,0.75,1.17,2.26,,77.62,AAP,-1.91167,0.213352,0.00476483,0.990027 beta-lactamase_625_L196E,beta-lactamase_625_196,TEM-1,beta-lactamase_625,P62593,0.990027,NO,196,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-2.478,-3.033,0.555,,0.518,S,A,0.55,1.35,12.152,12.152,77.62,AHH,-1.839,0.213352,0.00512144,0.990027 beta-lactamase_D207R,beta-lactamase_207,TEM-1,beta-lactamase,P62593,0.990028,NO,207,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.064,-2.841,0.777,5.40404,0.409,H,A,0.23,0.12,1.975,,77.62,HAH,-1.77033,0.221079,0.00592942,0.990028 beta-lactamase_625_R63A,beta-lactamase_625_63,TEM-1,beta-lactamase_625,P62593,0.990029,NO,63,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-0.943,-3.103,2.16,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.213352,0.00126938,0.990029 beta-lactamase_156_R220Q,beta-lactamase_156_220,TEM-1,beta-lactamase_156,P62593,0.990031,NO,220,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-0.942,-3.517,2.575,,0.295,I,A,1.2,-0.76,2.164,,74.48,HBP,-1.33633,0.111618,0.00232421,0.990031 beta-lactamase_625_T269H,beta-lactamase_625_269,TEM-1,beta-lactamase_625,P62593,0.990036,NO,269,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.213352,0.00950944,0.990036 PSD95pdz3_R312D,PSD95pdz3_312,PSD95pdz3,PSD95pdz3,P31016,0.990039,NO,312,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.582,-3.375,1.793,5.76826,,,,,12.2409,,,,OBB,-1.46667,0.0758425,0.00196255,0.990039 beta-lactamase_39_T264M,beta-lactamase_39_264,TEM-1,beta-lactamase_39,P62593,0.99004,NO,264,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.0495842,0.0119399,0.99004 kka2_1:8_L212C,kka2_1:8_212,Kka2,kka2_1:8,P00552,0.990043,NO,212,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.904,-4.688,3.784,,,,B,1.59,-0.78,1.708,,42.42,BHO,-0.799667,0.100394,0.0031426,0.990043 kka2_1:8_L212C,kka2_1:8_212,Kka2,kka2_1:8,P00552,0.990043,NO,212,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.904,-4.688,3.784,,,,B,1.59,-0.78,1.708,,42.42,BHO,-0.799667,0.100394,0.0031426,0.990043 beta-lactamase_625_T187S,beta-lactamase_625_187,TEM-1,beta-lactamase_625,P62593,0.990044,NO,187,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.401,-2.134,0.733,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.213352,0.00491782,0.990044 gb1_N234D,gb1_234,gb1,gb1,P06654,0.990044,NO,234,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-2.055,-3.209,1.154,,,,,,,1.235,,45.54,HPO,-2.05067,0.177985,0.00242189,0.990044 beta-lactamase_39_G265T,beta-lactamase_39_265,TEM-1,beta-lactamase_39,P62593,0.990048,NO,265,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.0495842,0.00811926,0.990048 beta-lactamase_39_S233L,beta-lactamase_39_233,TEM-1,beta-lactamase_39,P62593,0.990049,NO,233,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.886,-3.357,1.471,,0.016,E,B,0.27,-1.01,5.361,,77.62,BPO,-1.17267,0.0495842,0.00311415,0.990049 beta-lactamase_39_G76M,beta-lactamase_39_76,TEM-1,beta-lactamase_39,P62593,0.99005,NO,76,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.189,-4.767,3.578,,,H,A,0.29,-0.67,2.145,,67.83,OOH,-1.22267,0.0495842,0.00476637,0.99005 beta-lactamase_2500_Q97P,beta-lactamase_2500_97,TEM-1,beta-lactamase_2500,P62593,0.990051,NO,97,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.072,-2.583,0.511,,0.823,G,A,0.64,2.42,1.157,,77.62,PPP,-2.43833,0.361275,0.0045116,0.990051 beta-lactamase_625_S96E,beta-lactamase_625_96,TEM-1,beta-lactamase_625,P62593,0.990051,NO,96,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.27,-2.567,0.297,,0.368,,b,0.27,0.39,5.244,,73.78,HPP,-2.019,0.213352,0.00551835,0.990051 beta-lactamase_2500_N98K,beta-lactamase_2500_98,TEM-1,beta-lactamase_2500,P62593,0.990053,NO,98,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-2.973,-2.653,-0.32,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.361275,0.00505389,0.990053 beta-lactamase_156_D113G,beta-lactamase_156_113,TEM-1,beta-lactamase_156,P62593,0.990054,NO,113,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.829,-2.42,0.591,,0.665,T,A,0.75,0.91,2.973,,73.08,PAO,-1.703,0.111618,0.00474112,0.990054 kka2_1:8_Y218D,kka2_1:8_218,Kka2,kka2_1:8,P00552,0.99006,NO,218,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-1.438,-3.939,2.501,,0.122,H,A,1.25,-0.69,2.923,,56.06,BHP,-1.17533,0.100394,0.0126098,0.99006 kka2_1:8_Y218D,kka2_1:8_218,Kka2,kka2_1:8,P00552,0.99006,NO,218,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-1.438,-3.939,2.501,,0.122,H,A,1.25,-0.69,2.923,,56.06,BHP,-1.17533,0.100394,0.0126098,0.99006 beta-lactamase_39_A124C,beta-lactamase_39_124,TEM-1,beta-lactamase_39,P62593,0.990062,NO,124,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.181,-4.594,3.413,,,H,A,0.46,-0.9,1.367,,64.34,HHH,-1.152,0.0495842,0.00481399,0.990062 beta-lactamase_156_E61L,beta-lactamase_156_61,TEM-1,beta-lactamase_156,P62593,0.990063,NO,61,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.115,-3.769,1.654,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.111618,0.00440955,0.990063 beta-lactamase_156_H287F,beta-lactamase_156_287,TEM-1,beta-lactamase_156,P62593,0.990065,NO,287,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,,,,,,,,,,,,,BBH,-1.111,0.111618,,0.990065 beta-lactamase_0_T138H,beta-lactamase_0_138,TEM-1,beta-lactamase_0,P62593,0.990071,NO,138,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.506,-4.649,2.143,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.0500837,0.00487868,0.990071 beta-lactamase_156_A268S,beta-lactamase_156_268,TEM-1,beta-lactamase_156,P62593,0.990072,NO,268,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.111618,0.0102525,0.990072 beta-lactamase_156_L192S,beta-lactamase_156_192,TEM-1,beta-lactamase_156,P62593,0.990072,NO,192,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.254,-3.616,2.362,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.111618,0.00558728,0.990072 beta-lactamase_0_D113R,beta-lactamase_0_113,TEM-1,beta-lactamase_0,P62593,0.990074,NO,113,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.829,-2.854,1.025,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.0500837,0.00474112,0.990074 beta-lactamase_156_L160C,beta-lactamase_156_160,TEM-1,beta-lactamase_156,P62593,0.990074,NO,160,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.977,-4.68,3.703,,0.022,,B,0.55,-0.6,1.095,,44.41,BHA,-0.936,0.111618,0.00193775,0.990074 beta-lactamase_39_L100P,beta-lactamase_39_100,TEM-1,beta-lactamase_39,P62593,0.990074,NO,100,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.218,-4.169,2.951,,0.343,,B,0.55,0.13,8.311,,63.29,AHH,-1.23467,0.0495842,0.00413885,0.990074 beta-lactamase_39_G154P,beta-lactamase_39_154,TEM-1,beta-lactamase_39,P62593,0.990075,NO,154,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.823,-3.881,3.058,,0.54,T,l,0.29,-0.56,1.151,,64.69,HOA,-1.635,0.0495842,0.00180205,0.990075 Pab1_L153M,Pab1_153,Pab1,Pab1,P04147,0.990084,NO,153,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.039,-3.622,2.583,,0.46,E,A,,-0.95,,,,HHP,-1.17667,0.175299,0.000321212,0.990084 beta-lactamase_39_A225W,beta-lactamase_39_225,TEM-1,beta-lactamase_39,P62593,0.990091,NO,225,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.845,-5.541,3.696,,1,T,B,0.46,-0.38,9.874,9.874,74.48,OHO,-1.39967,0.0495842,0.00465057,0.990091 beta-lactamase_156_L205F,beta-lactamase_156_205,TEM-1,beta-lactamase_156,P62593,0.990092,NO,205,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.922,-2.306,1.384,,,H,A,0.55,-0.46,0.678,,42.31,PHH,-1.57767,0.111618,0.00255802,0.990092 beta-lactamase_156_N98Y,beta-lactamase_156_98,TEM-1,beta-lactamase_156,P62593,0.990092,NO,98,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-2.973,-4.22,1.247,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.111618,0.00505389,0.990092 beta-lactamase_625_F149K,beta-lactamase_625_149,TEM-1,beta-lactamase_625,P62593,0.990094,NO,149,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.299,-3.859,2.56,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.213352,0.00418462,0.990094 beta-lactamase_2500_T138D,beta-lactamase_2500_138,TEM-1,beta-lactamase_2500,P62593,0.990095,NO,138,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.506,-2.325,-0.181,,0.662,H,A,0.22,-0.03,30.445,30.445,73.78,HPP,-1.81233,0.361275,0.00487868,0.990095 WW_domain_P172Q,WW_domain_172,Yap65,WW_domain,P46937,0.990095,NO,172,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.035,-3.676,2.641,,,,,,,,,,HOH,-1.233,0.153962,0.000991485,0.990095 beta-lactamase_156_E62D,beta-lactamase_156_62,TEM-1,beta-lactamase_156,P62593,0.990105,NO,62,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.193,-2.088,0.895,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.111618,0.00264802,0.990105 beta-lactamase_39_E272S,beta-lactamase_39_272,TEM-1,beta-lactamase_39,P62593,0.990106,NO,272,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.127,,,,0.081,H,A,0.43,-0.97,12.983,12.983,63.64,AAB,-1.56333,0.0495842,0.00545371,0.990106 beta-lactamase_39_Q97C,beta-lactamase_39_97,TEM-1,beta-lactamase_39,P62593,0.990108,NO,97,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.072,-5.163,3.091,,0.823,G,A,0.64,2.42,4.457,,77.62,PPP,-2.43833,0.0495842,0.0045116,0.990108 beta-lactamase_39_R81A,beta-lactamase_39_81,TEM-1,beta-lactamase_39,P62593,0.990108,NO,81,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.466,-2.609,1.143,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.0495842,0.00499763,0.990108 beta-lactamase_156_T269V,beta-lactamase_156_269,TEM-1,beta-lactamase_156,P62593,0.99011,NO,269,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.111618,0.00950944,0.99011 beta-lactamase_625_H156Y,beta-lactamase_625_156,TEM-1,beta-lactamase_625,P62593,0.990119,NO,156,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-3.156,-4.359,1.203,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.213352,0.00468596,0.990119 beta-lactamase_S122V,beta-lactamase_122,TEM-1,beta-lactamase,P62593,0.990125,NO,122,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.406,-2.967,0.561,4.87767,0.352,H,A,0.73,-0.54,1.581,,77.62,OPH,-1.39767,0.221079,0.00497825,0.990125 beta-lactamase_T139V,beta-lactamase_139,TEM-1,beta-lactamase,P62593,0.990125,NO,139,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.901,-3.468,1.567,5.69095,0.216,H,A,0.3,0.39,2.256,,77.62,PPH,-2.04667,0.221079,0.00441837,0.990125 beta-lactamase_2500_G85K,beta-lactamase_2500_85,TEM-1,beta-lactamase_2500,P62593,0.99013,NO,85,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.011,-2.219,1.208,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.361275,0.00252173,0.99013 beta-lactamase_156_T198M,beta-lactamase_156_198,TEM-1,beta-lactamase_156,P62593,0.990134,NO,198,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.168,-4.608,2.44,,0.489,,B,0.22,-0.13,10.771,10.771,73.78,HPH,-1.98767,0.111618,0.004311,0.990134 beta-lactamase_156_D36Q,beta-lactamase_156_36,TEM-1,beta-lactamase_156,P62593,0.99014,NO,36,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.732,-2.234,-0.498,,0.555,H,A,0.75,1.17,14.871,14.871,77.62,AAP,-1.91167,0.111618,0.00476483,0.99014 beta-lactamase_156_G76V,beta-lactamase_156_76,TEM-1,beta-lactamase_156,P62593,0.990143,NO,76,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.189,-3.485,2.296,,,H,A,0.29,-0.67,3.059,,67.83,OOH,-1.22267,0.111618,0.00476637,0.990143 beta-lactamase_625_V157L,beta-lactamase_625_157,TEM-1,beta-lactamase_625,P62593,0.990144,NO,157,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.751,-3.066,1.315,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.213352,0.00506849,0.990144 beta-lactamase_625_G43A,beta-lactamase_625_43,TEM-1,beta-lactamase_625,P62593,0.990145,NO,43,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.62,-2.853,2.233,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.213352,0.00120151,0.990145 kka2_1:8_R140E,kka2_1:8_140,Kka2,kka2_1:8,P00552,0.99015,NO,140,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.351,-3.33,1.979,,0.12,H,A,0.16,0.2,2.874,,53.03,BBH,-1.885,0.100394,0.00430167,0.99015 kka2_1:8_R140E,kka2_1:8_140,Kka2,kka2_1:8,P00552,0.99015,NO,140,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.351,-3.33,1.979,,0.12,H,A,0.16,0.2,2.874,,53.03,BBH,-1.885,0.100394,0.00430167,0.99015 beta-lactamase_39_S96R,beta-lactamase_39_96,TEM-1,beta-lactamase_39,P62593,0.990151,NO,96,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.27,-2.133,-0.137,,0.368,,b,0.27,0.39,2.516,,73.78,HPP,-2.019,0.0495842,0.00551835,0.990151 beta-lactamase_39_L137A,beta-lactamase_39_137,TEM-1,beta-lactamase_39,P62593,0.990153,NO,137,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.03,-3.142,2.112,,,H,A,0.55,-0.38,0.674,,42.31,HHP,-1.58933,0.0495842,0.00278599,0.990153 beta-lactamase_156_M153A,beta-lactamase_156_153,TEM-1,beta-lactamase_156,P62593,0.990157,NO,153,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-3.193,-2.415,-0.778,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.111618,0.00509109,0.990157 beta-lactamase_39_L55M,beta-lactamase_39_55,TEM-1,beta-lactamase_39,P62593,0.990158,NO,55,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.86,-4.329,2.469,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.0495842,0.00403741,0.990158 beta-lactamase_625_E102T,beta-lactamase_625_102,TEM-1,beta-lactamase_625,P62593,0.99016,NO,102,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.118,-2.156,0.038,,0.722,S,B,1.04,1.82,1.336,,73.08,HAH,-1.581,0.213352,0.00486633,0.99016 beta-lactamase_156_Q276M,beta-lactamase_156_276,TEM-1,beta-lactamase_156,P62593,0.990161,NO,276,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.111618,0.0191712,0.990161 Pab1_D151V,Pab1_151,Pab1,Pab1,P04147,0.990161,NO,151,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.399,-3.588,1.189,,,,,,,,,,OAH,-1.51767,0.175299,0.00228155,0.990161 beta-lactamase_39_T27D,beta-lactamase_39_27,TEM-1,beta-lactamase_39,P62593,0.990164,NO,27,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.905,-3.5,1.595,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.0495842,0.00306559,0.990164 beta-lactamase_156_G85R,beta-lactamase_156_85,TEM-1,beta-lactamase_156,P62593,0.990165,NO,85,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.011,-2.784,1.773,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.111618,0.00252173,0.990165 beta-lactamase_39_I140T,beta-lactamase_39_140,TEM-1,beta-lactamase_39,P62593,0.990173,NO,140,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.733,-2.748,1.015,,0.128,H,A,0.48,0.41,1.16,,73.08,PHO,-1.48733,0.0495842,0.00597777,0.990173 beta-lactamase_39_Q267H,beta-lactamase_39_267,TEM-1,beta-lactamase_39,P62593,0.990173,NO,267,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.0495842,0.0102128,0.990173 beta-lactamase_2500_Q267W,beta-lactamase_2500_267,TEM-1,beta-lactamase_2500,P62593,0.990176,NO,267,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.361275,0.0102128,0.990176 beta-lactamase_39_H156P,beta-lactamase_39_156,TEM-1,beta-lactamase_39,P62593,0.990178,NO,156,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-3.156,-2.552,-0.604,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.0495842,0.00468596,0.990178 beta-lactamase_625_D207F,beta-lactamase_625_207,TEM-1,beta-lactamase_625,P62593,0.990179,NO,207,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.064,-4.437,2.373,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.213352,0.00592942,0.990179 beta-lactamase_2500_G194A,beta-lactamase_2500_194,TEM-1,beta-lactamase_2500,P62593,0.99018,NO,194,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.396,-2.558,1.162,,0.276,S,b,0.29,0.36,3.593,,67.83,POA,-1.832,0.361275,0.00392163,0.99018 beta-lactamase_2500_V157F,beta-lactamase_2500_157,TEM-1,beta-lactamase_2500,P62593,0.990182,NO,157,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.751,-3.968,2.217,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.361275,0.00506849,0.990182 beta-lactamase_39_R162W,beta-lactamase_39_162,TEM-1,beta-lactamase_39,P62593,0.990184,NO,162,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.016,-5.367,4.351,,0.124,S,B,1.2,-0.37,31.656,31.656,64.69,ABH,-1.25,0.0495842,0.000561334,0.990184 beta-lactamase_156_R202S,beta-lactamase_156_202,TEM-1,beta-lactamase_156,P62593,0.99019,NO,202,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.292,-2.609,1.317,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.111618,0.00321899,0.99019 beta-lactamase_2500_M180S,beta-lactamase_2500_180,TEM-1,beta-lactamase_2500,P62593,0.990191,NO,180,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-2.795,-2.032,-0.763,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.361275,0.00552048,0.990191 beta-lactamase_156_R257S,beta-lactamase_156_257,TEM-1,beta-lactamase_156,P62593,0.990192,NO,257,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.111618,0.00756629,0.990192 beta-lactamase_39_A77L,beta-lactamase_39_77,TEM-1,beta-lactamase_39,P62593,0.990194,NO,77,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.234,-2.423,1.189,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.0495842,0.00282362,0.990194 beta-lactamase_39_A40S,beta-lactamase_39_40,TEM-1,beta-lactamase_39,P62593,0.990196,NO,40,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.402,-3.164,1.762,,0.155,S,B,0.46,0.21,0.783,,73.78,OHB,-1.40267,0.0495842,0.00490026,0.990196 beta-lactamase_2500_G226T,beta-lactamase_2500_226,TEM-1,beta-lactamase_2500,P62593,0.990197,NO,226,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.461,-3.599,2.138,,0.701,T,l,0.29,-0.25,5.086,,74.48,HOH,-1.42933,0.361275,0.00665294,0.990197 beta-lactamase_156_M180R,beta-lactamase_156_180,TEM-1,beta-lactamase_156,P62593,0.990207,NO,180,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-2.795,-3.843,1.048,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.111618,0.00552048,0.990207 beta-lactamase_625_R162S,beta-lactamase_625_162,TEM-1,beta-lactamase_625,P62593,0.990212,NO,162,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.016,-3.456,2.44,,0.124,S,B,1.2,-0.37,1.445,,64.69,ABH,-1.25,0.213352,0.000561334,0.990212 kka2_1:8_R121C,kka2_1:8_121,Kka2,kka2_1:8,P00552,0.990212,NO,121,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.552,-5.157,3.605,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.100394,0.00523326,0.990212 kka2_1:8_R121C,kka2_1:8_121,Kka2,kka2_1:8,P00552,0.990212,NO,121,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.552,-5.157,3.605,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.100394,0.00523326,0.990212 gb1_T281R,gb1_281,gb1,gb1,P06654,0.990215,NO,281,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.828,-2.303,0.475,,,,,,,1.038,,35.71,HPA,-1.63667,0.177985,0.00284418,0.990215 beta-lactamase_156_N173E,beta-lactamase_156_173,TEM-1,beta-lactamase_156,P62593,0.990216,NO,173,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-2.663,-3.453,0.79,,1.044,T,l,0.61,1.25,3.718,,77.62,OPA,-1.46633,0.111618,0.0033769,0.990216 beta-lactamase_156_K32S,beta-lactamase_156_32,TEM-1,beta-lactamase_156,P62593,0.99022,NO,32,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.984,-3.371,1.387,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.111618,0.00401283,0.99022 beta-lactamase_625_P165R,beta-lactamase_625_165,TEM-1,beta-lactamase_625,P62593,0.990223,NO,165,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.373,-3.877,2.504,,0.203,T,A,0.52,-0.31,0.414,,73.78,AOA,-1.359,0.213352,0.00549538,0.990223 beta-lactamase_39_A222G,beta-lactamase_39_222,TEM-1,beta-lactamase_39,P62593,0.990225,NO,222,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.103,-1.732,-0.371,,0.233,H,A,0.46,-0.25,1.448,,77.62,PHH,-1.63733,0.0495842,0.00466094,0.990225 beta-lactamase_625_D271F,beta-lactamase_625_271,TEM-1,beta-lactamase_625,P62593,0.990236,NO,271,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.213352,0.00752082,0.990236 beta-lactamase_625_T147Q,beta-lactamase_625_147,TEM-1,beta-lactamase_625,P62593,0.990239,NO,147,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.149,-3.979,2.83,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.213352,0.00226017,0.990239 beta-lactamase_E102M,beta-lactamase_102,TEM-1,beta-lactamase,P62593,0.990239,NO,102,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.118,-4.799,2.681,6.36157,0.722,S,B,1.5,1.82,1.336,,73.08,HAH,-1.581,0.221079,0.00486633,0.990239 beta-lactamase_E175C,beta-lactamase_175,TEM-1,beta-lactamase,P62593,0.990239,NO,175,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.336,-5.076,2.74,6.0311,0.551,,A,0.75,1.05,5.316,,77.62,AAB,-1.31233,0.221079,0.00482205,0.990239 beta-lactamase_E237Y,beta-lactamase_237,TEM-1,beta-lactamase,P62593,0.990239,NO,237,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.058,-4.364,2.306,5.42877,0.583,S,B,1.62,1.2,2.144,,77.62,OAB,-1.61467,0.221079,0.0048626,0.990239 beta-lactamase_Q265D,beta-lactamase_265,TEM-1,beta-lactamase,P62593,0.990239,NO,265,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.58,-2.265,-0.315,6.62674,1.116,,A,0.03,1.17,12.514,12.514,69.58,PPH,-1.978,0.221079,0.00811926,0.990239 beta-lactamase_S122A,beta-lactamase_122,TEM-1,beta-lactamase,P62593,0.990239,NO,122,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.406,-2.18,-0.226,4.87767,0.352,H,A,0.73,-0.54,1.581,,77.62,OPH,-1.39767,0.221079,0.00497825,0.990239 beta-lactamase_T138C,beta-lactamase_138,TEM-1,beta-lactamase,P62593,0.990239,NO,138,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.506,-5.125,2.619,5.52585,0.662,H,A,0.3,-0.03,30.445,30.445,73.78,HPP,-1.81233,0.221079,0.00487868,0.990239 beta-lactamase_156_H287L,beta-lactamase_156_287,TEM-1,beta-lactamase_156,P62593,0.990243,NO,287,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,,,,,,,,,,,,,BBH,-1.111,0.111618,,0.990243 beta-lactamase_39_T269G,beta-lactamase_39_269,TEM-1,beta-lactamase_39,P62593,0.990243,NO,269,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.156,,,,0.646,H,A,0.53,0.4,3.889,,77.62,HPH,-1.96733,0.0495842,0.00950944,0.990243 beta-lactamase_156_E169R,beta-lactamase_156_169,TEM-1,beta-lactamase_156,P62593,0.990244,NO,169,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.23,-3.638,2.408,,0.337,,A,1.04,1,3.516,,73.08,PAH,-1.16533,0.111618,0.00400994,0.990244 beta-lactamase_39_I245M,beta-lactamase_39_245,TEM-1,beta-lactamase_39,P62593,0.990246,NO,245,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.0495842,0.00391032,0.990246 beta-lactamase_625_S256T,beta-lactamase_625_256,TEM-1,beta-lactamase_625,P62593,0.990247,NO,256,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.213352,0.00710634,0.990247 beta-lactamase_156_E238S,beta-lactamase_156_238,TEM-1,beta-lactamase_156,P62593,0.990249,NO,238,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.111618,0.00743256,0.990249 Pab1_D136A,Pab1_136,Pab1,Pab1,P04147,0.990252,NO,136,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.602,-1.563,-0.039,,,,,,,,,,OAH,-1.42367,0.175299,0.00227029,0.990252 beta-lactamase_625_I258A,beta-lactamase_625_258,TEM-1,beta-lactamase_625,P62593,0.990255,NO,258,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.213352,0.007931,0.990255 beta-lactamase_625_P165I,beta-lactamase_625_165,TEM-1,beta-lactamase_625,P62593,0.990261,NO,165,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.373,-3.815,2.442,,0.203,T,A,0.52,-0.31,0.414,,73.78,AOA,-1.359,0.213352,0.00549538,0.990261 beta-lactamase_156_L28W,beta-lactamase_156_28,TEM-1,beta-lactamase_156,P62593,0.990262,NO,28,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.579,-5.332,3.753,,0.277,H,A,0.55,-0.16,3.262,,93.01,PHH,-2.11333,0.111618,0.00359321,0.990262 beta-lactamase_39_Y262A,beta-lactamase_39_262,TEM-1,beta-lactamase_39,P62593,0.990263,NO,262,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.0495842,0.00853516,0.990263 beta-lactamase_39_A185I,beta-lactamase_39_185,TEM-1,beta-lactamase_39,P62593,0.990267,NO,185,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.406,-3.361,1.955,,,H,A,0.46,-1.02,2.68,,65.03,HHP,-1.84033,0.0495842,0.00467449,0.990267 beta-lactamase_39_Q276P,beta-lactamase_39_276,TEM-1,beta-lactamase_39,P62593,0.990268,NO,276,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.0495842,0.0191712,0.990268 beta-lactamase_156_N152Q,beta-lactamase_156_152,TEM-1,beta-lactamase_156,P62593,0.990269,NO,152,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-2.757,-2.534,-0.223,,0.863,H,A,0.61,0.92,4.038,,77.62,BPH,-2.97,0.111618,0.00471429,0.990269 E1_Ubiquitin_F45A,E1_Ubiquitin_45,Uba1,E1_Ubiquitin,P0CG63,0.990274,NO,45,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.149,-3.12,1.971,,0.26,E,B,,-0.99,,,,HHH,-1.316,0.18783,0.00193245,0.990274 E1_Ubiquitin_F45V,E1_Ubiquitin_45,Uba1,E1_Ubiquitin,P0CG63,0.990274,NO,45,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.149,-3.121,1.972,,0.26,E,B,,-0.99,,,,HHH,-1.316,0.18783,0.00193245,0.990274 E1_Ubiquitin_G47S,E1_Ubiquitin_47,Uba1,E1_Ubiquitin,P0CG63,0.990274,NO,47,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.999,-3.031,2.032,,0.057,T,l,,-1.21,,,,HOB,-1.195,0.18783,0.00142261,0.990274 E1_Ubiquitin_G47W,E1_Ubiquitin_47,Uba1,E1_Ubiquitin,P0CG63,0.990274,NO,47,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.999,-4.968,3.969,,0.057,T,l,,-1.21,,,,HOB,-1.195,0.18783,0.00142261,0.990274 E1_Ubiquitin_L43I,E1_Ubiquitin_43,Uba1,E1_Ubiquitin,P0CG63,0.990274,NO,43,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.188,-2.883,1.695,,,E,B,,-1.17,,,,BHH,-1.30733,0.18783,0.00190185,0.990274 E1_Ubiquitin_L73A,E1_Ubiquitin_73,Uba1,E1_Ubiquitin,P0CG63,0.990274,NO,73,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.039,-2.895,1.856,,0.518,,B,1.3,1,,,,BHB,-1.175,0.18783,0.00111236,0.990274 E1_Ubiquitin_R42V,E1_Ubiquitin_42,Uba1,E1_Ubiquitin,P0CG63,0.990274,NO,42,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.302,-3.564,2.262,,0.244,E,B,,-0.54,,,,PBH,-1.24667,0.18783,0.00224033,0.990274 E1_Ubiquitin_R74E,E1_Ubiquitin_74,Uba1,E1_Ubiquitin,P0CG63,0.990274,NO,74,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.302,-3.025,1.723,,0.838,T,A,,3.15,,,,HBO,-1.11333,0.18783,0.00180798,0.990274 E1_Ubiquitin_R74Q,E1_Ubiquitin_74,Uba1,E1_Ubiquitin,P0CG63,0.990274,NO,74,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.302,-3.32,2.018,,0.838,T,A,,3.15,,,,HBO,-1.11333,0.18783,0.00180798,0.990274 E1_Ubiquitin_R74T,E1_Ubiquitin_74,Uba1,E1_Ubiquitin,P0CG63,0.990274,NO,74,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.302,-3.292,1.99,,0.838,T,A,,3.15,,,,HBO,-1.11333,0.18783,0.00180798,0.990274 beta-lactamase_39_R275W,beta-lactamase_39_275,TEM-1,beta-lactamase_39,P62593,0.990277,NO,275,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.0495842,0.0141984,0.990277 PSD95pdz3_S350I,PSD95pdz3_350,PSD95pdz3,PSD95pdz3,P31016,0.990278,NO,350,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.519,-3.467,1.948,4.97629,,,,,25.01,,,,HPO,-1.29133,0.0758425,0.000704883,0.990278 beta-lactamase_625_T264W,beta-lactamase_625_264,TEM-1,beta-lactamase_625,P62593,0.990282,NO,264,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.213352,0.0119399,0.990282 beta-lactamase_A77A,beta-lactamase_77,TEM-1,beta-lactamase,P62593,0.990286,NO,77,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.234,-1.234,,4.75777,0.039,H,A,0.52,-0.56,1.708,,64.34,OHH,-1.294,0.221079,0.00282362,0.990286 beta-lactamase_2500_A148Q,beta-lactamase_2500_148,TEM-1,beta-lactamase_2500,P62593,0.990289,NO,148,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.757,-3.083,1.326,,0.379,H,A,0.46,-0.55,2.117,,72.73,PHH,-1.40167,0.361275,0.00547053,0.990289 kka2_1:1_F20V,kka2_1:1_20,Kka2,kka2_1:1,P00552,0.99029,NO,20,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-3.354,-2.808,-0.546,,0.935,T,B,0.58,-0.41,1.657,,92.05,HHO,-1.992,0.520039,0.00701744,0.99029 beta-lactamase_156_I140E,beta-lactamase_156_140,TEM-1,beta-lactamase_156,P62593,0.990292,NO,140,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.733,-3.925,2.192,,0.128,H,A,0.48,0.41,1.16,,73.08,PHO,-1.48733,0.111618,0.00597777,0.990292 beta-lactamase_625_E145P,beta-lactamase_625_145,TEM-1,beta-lactamase_625,P62593,0.990293,NO,145,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.357,-3.914,1.557,,0.545,H,A,1.04,0.79,2.64,,77.62,BAH,-2.069,0.213352,0.00553285,0.990293 beta-lactamase_625_K254I,beta-lactamase_625_254,TEM-1,beta-lactamase_625,P62593,0.990293,NO,254,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.213352,0.00369,0.990293 beta-lactamase_0_R239S,beta-lactamase_0_239,TEM-1,beta-lactamase_0,P62593,0.990305,NO,239,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.0500837,0.00213852,0.990305 beta-lactamase_2500_K254D,beta-lactamase_2500_254,TEM-1,beta-lactamase_2500,P62593,0.990311,NO,254,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.361275,0.00369,0.990311 beta-lactamase_39_E56S,beta-lactamase_39_56,TEM-1,beta-lactamase_39,P62593,0.990311,NO,56,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.043,-2.169,0.126,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.0495842,0.00238534,0.990311 beta-lactamase_625_H287G,beta-lactamase_625_287,TEM-1,beta-lactamase_625,P62593,0.990312,NO,287,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,,,,,,,,,,,,,BBH,-1.111,0.213352,,0.990312 beta-lactamase_156_G141R,beta-lactamase_156_141,TEM-1,beta-lactamase_156,P62593,0.990318,NO,141,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.828,-3.94,3.112,,0.575,T,l,0.29,-0.28,0.198,,64.69,HOO,-1.08933,0.111618,0.0012419,0.990318 beta-lactamase_156_L196V,beta-lactamase_156_196,TEM-1,beta-lactamase_156,P62593,0.990319,NO,196,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-2.478,-2.258,-0.22,,0.518,S,A,0.55,1.35,7.897,,77.62,AHH,-1.839,0.111618,0.00512144,0.990319 beta-lactamase_625_S122L,beta-lactamase_625_122,TEM-1,beta-lactamase_625,P62593,0.99032,NO,122,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.406,-2.918,0.512,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.213352,0.00497825,0.99032 beta-lactamase_625_T147C,beta-lactamase_625_147,TEM-1,beta-lactamase_625,P62593,0.990321,NO,147,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.149,-4.804,3.655,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.213352,0.00226017,0.990321 beta-lactamase_625_E102W,beta-lactamase_625_102,TEM-1,beta-lactamase_625,P62593,0.990323,NO,102,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.118,-5.479,3.361,,0.722,S,B,1.04,1.82,1.336,,73.08,HAH,-1.581,0.213352,0.00486633,0.990323 beta-lactamase_625_G90Y,beta-lactamase_625_90,TEM-1,beta-lactamase_625,P62593,0.990325,NO,90,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-2.091,-4.355,2.264,,0.598,T,A,0.29,0.32,0.319,,77.62,HOB,-1.52633,0.213352,0.00490273,0.990325 beta-lactamase_39_V82S,beta-lactamase_39_82,TEM-1,beta-lactamase_39,P62593,0.990327,NO,82,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.325,-3.501,2.176,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.0495842,0.00397046,0.990327 beta-lactamase_156_Q97H,beta-lactamase_156_97,TEM-1,beta-lactamase_156,P62593,0.990328,NO,97,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.072,-4.636,2.564,,0.823,G,A,0.64,2.42,4.457,,77.62,PPP,-2.43833,0.111618,0.0045116,0.990328 beta-lactamase_156_L196E,beta-lactamase_156_196,TEM-1,beta-lactamase_156,P62593,0.99033,NO,196,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-2.478,-3.033,0.555,,0.518,S,A,0.55,1.35,7.897,,77.62,AHH,-1.839,0.111618,0.00512144,0.99033 beta-lactamase_39_L111F,beta-lactamase_39_111,TEM-1,beta-lactamase_39,P62593,0.990338,NO,111,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.76,-2.976,1.216,,0.328,T,A,0.55,0.93,4.334,,64.34,BHP,-1.884,0.0495842,0.00480671,0.990338 beta-lactamase_625_E56R,beta-lactamase_625_56,TEM-1,beta-lactamase_625,P62593,0.99034,NO,56,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.043,-3.679,1.636,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.213352,0.00238534,0.99034 beta-lactamase_156_T198V,beta-lactamase_156_198,TEM-1,beta-lactamase_156,P62593,0.990345,NO,198,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.168,-2.827,0.659,,0.489,,B,0.22,-0.13,10.771,10.771,73.78,HPH,-1.98767,0.111618,0.004311,0.990345 beta-lactamase_E270A,beta-lactamase_270,TEM-1,beta-lactamase,P62593,0.990347,NO,270,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.723,-2.191,0.468,5.33196,0.422,H,A,0.52,1.15,1.745,,64.34,AAB,-1.70933,0.221079,0.00767762,0.990347 beta-lactamase_E270Q,beta-lactamase_270,TEM-1,beta-lactamase,P62593,0.990347,NO,270,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.723,-2.554,0.831,5.33196,0.422,H,A,0.52,1.15,1.745,,64.34,AAB,-1.70933,0.221079,0.00767762,0.990347 beta-lactamase_625_E145Y,beta-lactamase_625_145,TEM-1,beta-lactamase_625,P62593,0.990348,NO,145,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.357,-4.381,2.024,,0.545,H,A,1.04,0.79,2.64,,77.62,BAH,-2.069,0.213352,0.00553285,0.990348 beta-lactamase_156_S266Y,beta-lactamase_156_266,TEM-1,beta-lactamase_156,P62593,0.99035,NO,266,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.111618,0.0140785,0.99035 beta-lactamase_39_Q37N,beta-lactamase_39_37,TEM-1,beta-lactamase_39,P62593,0.99035,NO,37,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.134,-3.706,1.572,,0.613,H,A,0.64,1.98,22.282,22.282,73.08,APH,-2.06967,0.0495842,0.00425833,0.99035 beta-lactamase_156_S80A,beta-lactamase_156_80,TEM-1,beta-lactamase_156,P62593,0.990366,NO,80,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.029,-1.631,-0.398,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.111618,0.00565569,0.990366 beta-lactamase_39_L191E,beta-lactamase_39_191,TEM-1,beta-lactamase_39,P62593,0.990366,NO,191,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.087,-3.859,2.772,,,H,A,0.55,0.09,1.372,,63.29,BHH,-1.445,0.0495842,0.00263549,0.990366 beta-lactamase_39_G39A,beta-lactamase_39_39,TEM-1,beta-lactamase_39,P62593,0.990371,NO,39,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.864,-2.728,0.864,,0.701,T,L,0.29,0.47,1.454,,77.62,HOH,-1.53633,0.0495842,0.00487611,0.990371 beta-lactamase_39_L47M,beta-lactamase_39_47,TEM-1,beta-lactamase_39,P62593,0.990375,NO,47,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.876,-2.629,0.753,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.0495842,0.00439844,0.990375 beta-lactamase_625_S80G,beta-lactamase_625_80,TEM-1,beta-lactamase_625,P62593,0.990375,NO,80,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.029,-3.327,1.298,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.213352,0.00565569,0.990375 beta-lactamase_0_G114K,beta-lactamase_0_114,TEM-1,beta-lactamase_0,P62593,0.990377,NO,114,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.094,-3.566,2.472,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.0500837,0.00224919,0.990377 beta-lactamase_156_H24G,beta-lactamase_156_24,TEM-1,beta-lactamase_156,P62593,0.990378,NO,24,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-2.481,-2.499,0.018,,,,,,,2.708,,93.01,OBO,-2.0035,0.111618,0.00238894,0.990378 beta-lactamase_39_W163L,beta-lactamase_39_163,TEM-1,beta-lactamase_39,P62593,0.990385,NO,163,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-1.843,-2.838,0.995,,0.467,,B,0.47,-0.5,15.095,15.095,63.99,BHA,-1.269,0.0495842,0.00418955,0.990385 beta-lactamase_625_S96Q,beta-lactamase_625_96,TEM-1,beta-lactamase_625,P62593,0.99039,NO,96,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.27,-2.919,0.649,,0.368,,b,0.27,0.39,5.244,,73.78,HPP,-2.019,0.213352,0.00551835,0.99039 beta-lactamase_625_T264S,beta-lactamase_625_264,TEM-1,beta-lactamase_625,P62593,0.990393,NO,264,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.985,-1.764,-0.221,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.213352,0.0119399,0.990393 beta-lactamase_156_E46N,beta-lactamase_156_46,TEM-1,beta-lactamase_156,P62593,0.990398,NO,46,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.94,-4.011,2.071,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.111618,0.00427568,0.990398 beta-lactamase_156_R159K,beta-lactamase_156_159,TEM-1,beta-lactamase_156,P62593,0.990404,NO,159,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-0.94,-2.865,1.925,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.111618,0.00108472,0.990404 beta-lactamase_39_T187K,beta-lactamase_39_187,TEM-1,beta-lactamase_39,P62593,0.990406,NO,187,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.401,-3.578,2.177,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.0495842,0.00491782,0.990406 beta-lactamase_156_D174M,beta-lactamase_156_174,TEM-1,beta-lactamase_156,P62593,0.990408,NO,174,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.738,-4.93,4.192,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.111618,0.00125633,0.990408 beta-lactamase_39_A225F,beta-lactamase_39_225,TEM-1,beta-lactamase_39,P62593,0.990409,NO,225,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.845,-4.402,2.557,,1,T,B,0.46,-0.38,9.874,9.874,74.48,OHO,-1.39967,0.0495842,0.00465057,0.990409 Pab1_Q194V,Pab1_194,Pab1,Pab1,P04147,0.99041,NO,194,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.179,-3.405,1.226,,,,,,,,,,OPA,-1.59767,0.175299,0.0016145,0.99041 beta-lactamase_625_P105Q,beta-lactamase_625_105,TEM-1,beta-lactamase_625,P62593,0.990412,NO,105,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.813,-3.897,3.084,,0.226,T,A,0.52,0.8,1.154,,63.29,POH,-1.01533,0.213352,0.0011981,0.990412 beta-lactamase_39_L111D,beta-lactamase_39_111,TEM-1,beta-lactamase_39,P62593,0.990413,NO,111,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.76,-3.995,2.235,,0.328,T,A,0.55,0.93,4.334,,64.34,BHP,-1.884,0.0495842,0.00480671,0.990413 beta-lactamase_2500_G90T,beta-lactamase_2500_90,TEM-1,beta-lactamase_2500,P62593,0.990415,NO,90,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-2.091,-2.913,0.822,,0.598,T,A,0.29,0.32,1.2,,77.62,HOB,-1.52633,0.361275,0.00490273,0.990415 beta-lactamase_39_N98R,beta-lactamase_39_98,TEM-1,beta-lactamase_39,P62593,0.990421,NO,98,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-2.973,-2.618,-0.355,,0.963,G,A,0.61,1.35,14.853,14.853,77.62,PPA,-2.07867,0.0495842,0.00505389,0.990421 beta-lactamase_2500_A282L,beta-lactamase_2500_282,TEM-1,beta-lactamase_2500,P62593,0.990424,NO,282,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.586,-3.183,1.597,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.361275,0.0449821,0.990424 beta-lactamase_2500_Q97T,beta-lactamase_2500_97,TEM-1,beta-lactamase_2500,P62593,0.990427,NO,97,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.072,-2.713,0.641,,0.823,G,A,0.64,2.42,1.157,,77.62,PPP,-2.43833,0.361275,0.0045116,0.990427 beta-lactamase_39_L199A,beta-lactamase_39_199,TEM-1,beta-lactamase_39,P62593,0.990427,NO,199,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-2.942,-2.055,-0.887,,0.832,H,A,0.55,0.42,15.504,15.504,77.62,PHH,-2.32933,0.0495842,0.0048649,0.990427 beta-lactamase_156_D231E,beta-lactamase_156_231,TEM-1,beta-lactamase_156,P62593,0.990428,NO,231,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.816,-2.232,1.416,,,E,B,0.75,-1.06,2.66,,65.38,HAB,-0.994,0.111618,0.00107395,0.990428 beta-lactamase_P143P,beta-lactamase_143,TEM-1,beta-lactamase,P62593,0.990428,NO,143,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.967,-0.967,,5.16366,0.075,H,A,0.99,-0.37,0.479,,66.78,OOB,-1.354,0.221079,0.00114551,0.990428 beta-lactamase_625_G216H,beta-lactamase_625_216,TEM-1,beta-lactamase_625,P62593,0.990429,NO,216,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.477,-4.598,3.121,,0.437,I,A,0.29,-0.58,1.718,,74.48,HOO,-1.68067,0.213352,0.00639568,0.990429 beta-lactamase_39_S57N,beta-lactamase_39_57,TEM-1,beta-lactamase_39,P62593,0.990431,NO,57,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.918,-2.953,1.035,,0.352,E,B,0.27,-0.18,2.3,,72.73,APH,-2.29167,0.0495842,0.00492804,0.990431 beta-lactamase_156_H110Q,beta-lactamase_156_110,TEM-1,beta-lactamase_156,P62593,0.990438,NO,110,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-1.706,-2.734,1.028,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.111618,0.00441499,0.990438 beta-lactamase_39_A215T,beta-lactamase_39_215,TEM-1,beta-lactamase_39,P62593,0.99044,NO,215,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.503,-2.291,0.788,,,,a,0.46,-0.93,0.494,,74.48,HHO,-1.42633,0.0495842,0.00544007,0.99044 beta-lactamase_39_R162Y,beta-lactamase_39_162,TEM-1,beta-lactamase_39,P62593,0.990446,NO,162,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.016,-4.207,3.191,,0.124,S,B,1.2,-0.37,31.656,31.656,64.69,ABH,-1.25,0.0495842,0.000561334,0.990446 beta-lactamase_625_T198M,beta-lactamase_625_198,TEM-1,beta-lactamase_625,P62593,0.990463,NO,198,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.168,-4.608,2.44,,0.489,,B,0.22,-0.13,0.37,,73.78,HPH,-1.98767,0.213352,0.004311,0.990463 beta-lactamase_39_R63N,beta-lactamase_39_63,TEM-1,beta-lactamase_39,P62593,0.990464,NO,63,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-0.943,-3.531,2.588,,0.218,,B,1.2,-0.31,0.326,,44.06,ABH,-0.992333,0.0495842,0.00126938,0.990464 beta-lactamase_625_R81L,beta-lactamase_625_81,TEM-1,beta-lactamase_625,P62593,0.990464,NO,81,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.466,-2.766,1.3,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.213352,0.00499763,0.990464 beta-lactamase_2500_N50A,beta-lactamase_2500_50,TEM-1,beta-lactamase_2500,P62593,0.990465,NO,50,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-2.979,-1.868,-1.111,,0.912,T,A,0.61,1.24,1.581,,77.62,HPP,-2.134,0.361275,0.0047211,0.990465 beta-lactamase_156_V117P,beta-lactamase_156_117,TEM-1,beta-lactamase_156,P62593,0.990466,NO,117,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.53,-4.14,2.61,,,H,A,0.44,-0.34,1.182,,65.03,PHB,-1.741,0.111618,0.00467906,0.990466 beta-lactamase_625_Q276G,beta-lactamase_625_276,TEM-1,beta-lactamase_625,P62593,0.990466,NO,276,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.213352,0.0191712,0.990466 beta-lactamase_A200T,beta-lactamase_200,TEM-1,beta-lactamase,P62593,0.990472,NO,200,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.878,-2.493,0.615,5.19406,0.757,H,A,0.47,-0.19,0.436,,77.62,HHP,-2.001,0.221079,0.0060056,0.990472 beta-lactamase_T138D,beta-lactamase_138,TEM-1,beta-lactamase,P62593,0.990472,NO,138,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.506,-2.325,-0.181,5.52585,0.662,H,A,0.3,-0.03,30.445,30.445,73.78,HPP,-1.81233,0.221079,0.00487868,0.990472 beta-lactamase_156_L196A,beta-lactamase_156_196,TEM-1,beta-lactamase_156,P62593,0.990476,NO,196,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-2.478,-1.974,-0.504,,0.518,S,A,0.55,1.35,7.897,,77.62,AHH,-1.839,0.111618,0.00512144,0.990476 beta-lactamase_2500_P60R,beta-lactamase_2500_60,TEM-1,beta-lactamase_2500,P62593,0.990478,NO,60,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-2.469,-3.014,0.545,,0.256,T,A,0.52,-0.56,1.581,,77.62,BOA,-1.97633,0.361275,0.00521318,0.990478 beta-lactamase_0_A124G,beta-lactamase_0_124,TEM-1,beta-lactamase_0,P62593,0.990482,NO,124,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.181,-3.186,2.005,,,H,A,0.46,-0.9,1.876,,64.34,HHH,-1.152,0.0500837,0.00481399,0.990482 beta-lactamase_625_V214G,beta-lactamase_625_214,TEM-1,beta-lactamase_625,P62593,0.990484,NO,214,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.299,-3.571,2.272,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.213352,0.00628442,0.990484 beta-lactamase_156_H151Q,beta-lactamase_156_151,TEM-1,beta-lactamase_156,P62593,0.990488,NO,151,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-2.96,-2.497,-0.463,,0.594,H,A,0.17,0.1,1.401,,77.62,HBP,-2.34767,0.111618,0.00216946,0.990488 beta-lactamase_2500_G76S,beta-lactamase_2500_76,TEM-1,beta-lactamase_2500,P62593,0.990489,NO,76,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.189,-2.528,1.339,,,H,A,0.29,-0.67,1.012,,67.83,OOH,-1.22267,0.361275,0.00476637,0.990489 beta-lactamase_625_V101K,beta-lactamase_625_101,TEM-1,beta-lactamase_625,P62593,0.99049,NO,101,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.295,-3.742,2.447,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.213352,0.00374492,0.99049 beta-lactamase_156_H24Y,beta-lactamase_156_24,TEM-1,beta-lactamase_156,P62593,0.990507,NO,24,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-2.481,-4.052,1.571,,,,,,,2.708,,93.01,OBO,-2.0035,0.111618,0.00238894,0.990507 beta-lactamase_156_A170D,beta-lactamase_156_170,TEM-1,beta-lactamase_156,P62593,0.990512,NO,170,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.237,-3.712,2.475,,0.126,,L,0.46,-0.35,3.7,,64.69,AHH,-1.63267,0.111618,0.00431903,0.990512 beta-lactamase_39_R275V,beta-lactamase_39_275,TEM-1,beta-lactamase_39,P62593,0.990515,NO,275,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.0495842,0.0141984,0.990515 beta-lactamase_625_S104G,beta-lactamase_625_104,TEM-1,beta-lactamase_625,P62593,0.990516,NO,104,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.015,-3.017,2.002,,0.04,,b,0.27,0.57,1.76,,63.29,HPO,-1.05267,0.213352,0.00218083,0.990516 beta-lactamase_625_Q203W,beta-lactamase_625_203,TEM-1,beta-lactamase_625,P62593,0.990519,NO,203,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.168,-5.466,3.298,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.213352,0.00631514,0.990519 beta-lactamase_0_Q88V,beta-lactamase_0_88,TEM-1,beta-lactamase_0,P62593,0.990524,NO,88,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.086,-3.621,1.535,,0.807,,B,0.64,2.03,0.4,,77.62,APH,-1.53433,0.0500837,0.00504167,0.990524 beta-lactamase_156_A40I,beta-lactamase_156_40,TEM-1,beta-lactamase_156,P62593,0.990526,NO,40,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.402,-3.742,2.34,,0.155,S,B,0.46,0.21,1.357,,73.78,OHB,-1.40267,0.111618,0.00490026,0.990526 beta-lactamase_156_R275H,beta-lactamase_156_275,TEM-1,beta-lactamase_156,P62593,0.990528,NO,275,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.111618,0.0141984,0.990528 beta-lactamase_156_G265V,beta-lactamase_156_265,TEM-1,beta-lactamase_156,P62593,0.990529,NO,265,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.111618,0.00811926,0.990529 beta-lactamase_625_I171R,beta-lactamase_625_171,TEM-1,beta-lactamase_625,P62593,0.99053,NO,171,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-2.431,-2.473,0.042,,0.361,,B,0.48,0.53,3.869,,77.62,HHO,-1.55533,0.213352,0.00623355,0.99053 beta-lactamase_39_V31G,beta-lactamase_39_31,TEM-1,beta-lactamase_39,P62593,0.990531,NO,31,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.822,-3.699,1.877,,,H,A,0.44,-0.46,2.885,,73.78,BHB,-2.03767,0.0495842,0.00478065,0.990531 beta-lactamase_625_E279T,beta-lactamase_625_279,TEM-1,beta-lactamase_625,P62593,0.990533,NO,279,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.213352,0.0192826,0.990533 kka2_1:2_A56L,kka2_1:2_56,Kka2,kka2_1:2,P00552,0.990536,NO,56,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.083,-2.797,0.714,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.295029,0.00717715,0.990536 beta-lactamase_625_G90K,beta-lactamase_625_90,TEM-1,beta-lactamase_625,P62593,0.990538,NO,90,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-2.091,-3.514,1.423,,0.598,T,A,0.29,0.32,0.319,,77.62,HOB,-1.52633,0.213352,0.00490273,0.990538 beta-lactamase_H24E,beta-lactamase_24,TEM-1,beta-lactamase,P62593,0.990543,NO,24,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-2.481,-3.284,0.803,5.82767,,,,,,2.708,,93.01,HBO,-1.85167,0.221079,0.00238894,0.990543 beta-lactamase_156_E175G,beta-lactamase_156_175,TEM-1,beta-lactamase_156,P62593,0.990558,NO,175,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.336,-3.483,1.147,,0.551,,A,1.04,1.05,2.334,,77.62,AAB,-1.31233,0.111618,0.00482205,0.990558 beta-lactamase_156_D33T,beta-lactamase_156_33,TEM-1,beta-lactamase_156,P62593,0.990561,NO,33,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.321,-2.667,0.346,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.111618,0.00435556,0.990561 beta-lactamase_D250C,beta-lactamase_250,TEM-1,beta-lactamase,P62593,0.990568,NO,250,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.335,-5.172,2.837,5.72026,0.89,T,L,0.23,1.53,24.737,24.737,66.08,OAO,-1.85133,0.221079,0.00550899,0.990568 Pab1_G167G,Pab1_167,Pab1,Pab1,P04147,0.990571,NO,167,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.223,-1.223,,,0.195,S,g,,0.03,,,,BOH,-1.25133,0.175299,0.00146449,0.990571 beta-lactamase_156_E145T,beta-lactamase_156_145,TEM-1,beta-lactamase_156,P62593,0.990572,NO,145,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.357,-3.565,1.208,,0.545,H,A,1.04,0.79,3.661,,77.62,BAH,-2.069,0.111618,0.00553285,0.990572 beta-lactamase_625_S283F,beta-lactamase_625_283,TEM-1,beta-lactamase_625,P62593,0.990574,NO,283,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.213352,0.0429138,0.990574 beta-lactamase_625_D113Q,beta-lactamase_625_113,TEM-1,beta-lactamase_625,P62593,0.990576,NO,113,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.829,-2.873,1.044,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.213352,0.00474112,0.990576 Pab1_N187C,Pab1_187,Pab1,Pab1,P04147,0.990576,NO,187,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-1.224,-4.958,3.734,,0.456,S,b,,1.87,,,,HPO,-1.272,0.175299,0.00083165,0.990576 beta-lactamase_156_H156G,beta-lactamase_156_156,TEM-1,beta-lactamase_156,P62593,0.990577,NO,156,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-3.156,-2.688,-0.468,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.111618,0.00468596,0.990577 Pab1_D144N,Pab1_144,Pab1,Pab1,P04147,0.990578,NO,144,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.189,-3.184,1.995,,0.616,H,A,,0.6,,,,HAP,-1.40567,0.175299,0.00121131,0.990578 beta-lactamase_2500_I206M,beta-lactamase_2500_206,TEM-1,beta-lactamase_2500,P62593,0.990582,NO,206,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-2.429,-3.069,0.64,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.361275,0.00528934,0.990582 beta-lactamase_156_L160S,beta-lactamase_156_160,TEM-1,beta-lactamase_156,P62593,0.990583,NO,160,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.977,-3.653,2.676,,0.022,,B,0.55,-0.6,1.095,,44.41,BHA,-0.936,0.111618,0.00193775,0.990583 beta-lactamase_625_P172K,beta-lactamase_625_172,TEM-1,beta-lactamase_625,P62593,0.990584,NO,172,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.998,-3.522,2.524,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.213352,0.00312594,0.990584 kka2_1:8_D156R,kka2_1:8_156,Kka2,kka2_1:8,P00552,0.990584,NO,156,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.696,-3.967,2.271,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.100394,0.00926998,0.990584 kka2_1:8_D156R,kka2_1:8_156,Kka2,kka2_1:8,P00552,0.990584,NO,156,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.696,-3.967,2.271,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.100394,0.00926998,0.990584 beta-lactamase_156_G253Y,beta-lactamase_156_253,TEM-1,beta-lactamase_156,P62593,0.990585,NO,253,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.111618,0.00786358,0.990585 beta-lactamase_39_L111Y,beta-lactamase_39_111,TEM-1,beta-lactamase_39,P62593,0.990589,NO,111,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.76,-4.039,2.279,,0.328,T,A,0.55,0.93,4.334,,64.34,BHP,-1.884,0.0495842,0.00480671,0.990589 beta-lactamase_625_A211N,beta-lactamase_625_211,TEM-1,beta-lactamase_625,P62593,0.99059,NO,211,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.896,-2.729,0.833,,0.369,T,A,0.46,-0.69,2.061,,77.62,AHA,-1.94633,0.213352,0.00648183,0.99059 beta-lactamase_156_L218F,beta-lactamase_156_218,TEM-1,beta-lactamase_156,P62593,0.990591,NO,218,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.391,-2.985,1.594,,,I,b,0.55,-0.53,17.202,17.202,74.48,OHH,-1.58867,0.111618,0.00618274,0.990591 beta-lactamase_2500_S266T,beta-lactamase_2500_266,TEM-1,beta-lactamase_2500,P62593,0.990591,NO,266,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.361275,0.0140785,0.990591 beta-lactamase_39_G142V,beta-lactamase_39_142,TEM-1,beta-lactamase_39,P62593,0.990591,NO,142,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.707,-3.751,3.044,,0.034,,p,0.29,-0.64,1.947,,64.69,OOO,-0.834,0.0495842,0.00060149,0.990591 beta-lactamase_625_R92L,beta-lactamase_625_92,TEM-1,beta-lactamase_625,P62593,0.990591,NO,92,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.718,-2.788,1.07,,0.479,E,B,1.2,1.36,3.069,,65.38,BBH,-1.50367,0.213352,0.00429626,0.990591 Pab1_D151E,Pab1_151,Pab1,Pab1,P04147,0.990591,NO,151,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.399,-2.374,-0.025,,,,,,,,,,OAH,-1.51767,0.175299,0.00228155,0.990591 beta-lactamase_39_A215Q,beta-lactamase_39_215,TEM-1,beta-lactamase_39,P62593,0.990592,NO,215,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.503,-2.998,1.495,,,,a,0.46,-0.93,0.494,,74.48,HHO,-1.42633,0.0495842,0.00544007,0.990592 beta-lactamase_2500_A148F,beta-lactamase_2500_148,TEM-1,beta-lactamase_2500,P62593,0.990593,NO,148,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.757,-4.389,2.632,,0.379,H,A,0.46,-0.55,2.117,,72.73,PHH,-1.40167,0.361275,0.00547053,0.990593 beta-lactamase_39_T264H,beta-lactamase_39_264,TEM-1,beta-lactamase_39,P62593,0.990597,NO,264,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.0495842,0.0119399,0.990597 beta-lactamase_2500_N98D,beta-lactamase_2500_98,TEM-1,beta-lactamase_2500,P62593,0.990598,NO,98,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-2.973,-2.35,-0.623,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.361275,0.00505389,0.990598 beta-lactamase_625_E279V,beta-lactamase_625_279,TEM-1,beta-lactamase_625,P62593,0.990603,NO,279,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.213352,0.0192826,0.990603 beta-lactamase_0_L150C,beta-lactamase_0_150,TEM-1,beta-lactamase_0,P62593,0.990605,NO,150,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.326,-4.732,3.406,,,H,A,0.55,-0.2,2.128,,62.94,HHB,-1.86167,0.0500837,0.00463171,0.990605 beta-lactamase_2500_A200P,beta-lactamase_2500_200,TEM-1,beta-lactamase_2500,P62593,0.990605,NO,200,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.878,-2.581,0.703,,0.757,H,A,0.46,-0.19,0.436,,77.62,HHP,-2.001,0.361275,0.0060056,0.990605 beta-lactamase_0_G253Q,beta-lactamase_0_253,TEM-1,beta-lactamase_0,P62593,0.990607,NO,253,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.0500837,0.00786358,0.990607 beta-lactamase_156_S57E,beta-lactamase_156_57,TEM-1,beta-lactamase_156,P62593,0.990618,NO,57,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.918,-2.903,0.985,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.111618,0.00492804,0.990618 beta-lactamase_625_D99A,beta-lactamase_625_99,TEM-1,beta-lactamase_625,P62593,0.990621,NO,99,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.191,-2.613,1.422,,0.402,G,A,0.75,0.36,1.318,,64.69,PAH,-1.794,0.213352,0.00305446,0.990621 WW_domain_P172H,WW_domain_172,Yap65,WW_domain,P46937,0.990621,NO,172,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.035,-4.457,3.422,,,,,,,,,,HOH,-1.233,0.153962,0.000991485,0.990621 beta-lactamase_2500_S96V,beta-lactamase_2500_96,TEM-1,beta-lactamase_2500,P62593,0.990622,NO,96,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.27,-3.642,1.372,,0.368,,b,0.27,0.39,32.348,32.348,73.78,HPP,-2.019,0.361275,0.00551835,0.990622 beta-lactamase_156_K32D,beta-lactamase_156_32,TEM-1,beta-lactamase_156,P62593,0.99063,NO,32,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.984,-2.882,0.898,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.111618,0.00401283,0.99063 beta-lactamase_39_G249S,beta-lactamase_39_249,TEM-1,beta-lactamase_39,P62593,0.990636,NO,249,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.312,,,,0.256,S,B,0.23,0.04,30.841,30.841,72.73,HOO,-1.81367,0.0495842,0.00220169,0.990636 beta-lactamase_156_I140N,beta-lactamase_156_140,TEM-1,beta-lactamase_156,P62593,0.990638,NO,140,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.733,-4.2,2.467,,0.128,H,A,0.48,0.41,1.16,,73.08,PHO,-1.48733,0.111618,0.00597777,0.990638 beta-lactamase_625_M153I,beta-lactamase_625_153,TEM-1,beta-lactamase_625,P62593,0.99064,NO,153,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-3.193,-1.739,-1.454,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.213352,0.00509109,0.99064 beta-lactamase_2500_E87M,beta-lactamase_2500_87,TEM-1,beta-lactamase_2500,P62593,0.990644,NO,87,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.421,-4.574,3.153,,0.048,,B,1.04,0.92,17.923,17.923,64.69,PAP,-1.969,0.361275,0.00337888,0.990644 beta-lactamase_625_Q276E,beta-lactamase_625_276,TEM-1,beta-lactamase_625,P62593,0.990647,NO,276,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.213352,0.0191712,0.990647 beta-lactamase_2500_A247F,beta-lactamase_2500_247,TEM-1,beta-lactamase_2500,P62593,0.990656,NO,247,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.361275,0.00611275,0.990656 beta-lactamase_625_A77W,beta-lactamase_625_77,TEM-1,beta-lactamase_625,P62593,0.990664,NO,77,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.234,-5.367,4.133,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.213352,0.00282362,0.990664 beta-lactamase_156_R239E,beta-lactamase_156_239,TEM-1,beta-lactamase_156,P62593,0.990669,NO,239,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.111618,0.00213852,0.990669 beta-lactamase_156_G253S,beta-lactamase_156_253,TEM-1,beta-lactamase_156,P62593,0.990673,NO,253,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.111618,0.00786358,0.990673 beta-lactamase_2500_S201A,beta-lactamase_2500_201,TEM-1,beta-lactamase_2500,P62593,0.99068,NO,201,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.183,-2.127,0.944,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.361275,0.00198815,0.99068 beta-lactamase_156_L192W,beta-lactamase_156_192,TEM-1,beta-lactamase_156,P62593,0.990688,NO,192,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.254,-5.176,3.922,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.111618,0.00558728,0.990688 beta-lactamase_2500_H94L,beta-lactamase_2500_94,TEM-1,beta-lactamase_2500,P62593,0.990688,NO,94,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-2.5,-3.441,0.941,,0.776,,B,0.17,1.24,1.176,,77.62,HBH,-1.872,0.361275,0.00389226,0.990688 beta-lactamase_2500_A247T,beta-lactamase_2500_247,TEM-1,beta-lactamase_2500,P62593,0.990691,NO,247,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.361275,0.00611275,0.990691 beta-lactamase_156_L196M,beta-lactamase_156_196,TEM-1,beta-lactamase_156,P62593,0.990692,NO,196,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-2.478,-3.442,0.964,,0.518,S,A,0.55,1.35,7.897,,77.62,AHH,-1.839,0.111618,0.00512144,0.990692 beta-lactamase_156_G85N,beta-lactamase_156_85,TEM-1,beta-lactamase_156,P62593,0.990697,NO,85,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.011,-3.501,2.49,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.111618,0.00252173,0.990697 beta-lactamase_625_I206Q,beta-lactamase_625_206,TEM-1,beta-lactamase_625,P62593,0.990702,NO,206,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-2.429,-2.554,0.125,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.213352,0.00528934,0.990702 beta-lactamase_156_L135C,beta-lactamase_156_135,TEM-1,beta-lactamase_156,P62593,0.990703,NO,135,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.002,-4.691,3.689,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.111618,0.00244423,0.990703 beta-lactamase_156_I206H,beta-lactamase_156_206,TEM-1,beta-lactamase_156,P62593,0.990704,NO,206,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-2.429,-4.842,2.413,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.111618,0.00528934,0.990704 beta-lactamase_625_G154N,beta-lactamase_625_154,TEM-1,beta-lactamase_625,P62593,0.990707,NO,154,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.823,-3.507,2.684,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.213352,0.00180205,0.990707 beta-lactamase_D269Q,beta-lactamase_269,TEM-1,beta-lactamase,P62593,0.990717,NO,269,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.156,-3.066,0.91,5.47645,0.646,H,A,0.23,0.4,21.796,21.796,77.62,HAA,-1.96733,0.221079,0.00950944,0.990717 beta-lactamase_2500_Q86A,beta-lactamase_2500_86,TEM-1,beta-lactamase_2500,P62593,0.990723,NO,86,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.4,-2.601,0.201,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.361275,0.00450027,0.990723 beta-lactamase_A183T,beta-lactamase_183,TEM-1,beta-lactamase,P62593,0.990724,NO,183,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.231,-3.281,2.05,4.84712,0.155,H,A,0.55,-0.91,12.189,,77.62,HHH,-1.53367,0.221079,0.00296631,0.990724 beta-lactamase_156_N173L,beta-lactamase_156_173,TEM-1,beta-lactamase_156,P62593,0.990726,NO,173,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-2.663,-3.749,1.086,,1.044,T,l,0.61,1.25,3.718,,77.62,OPA,-1.46633,0.111618,0.0033769,0.990726 beta-lactamase_2500_L248V,beta-lactamase_2500_248,TEM-1,beta-lactamase_2500,P62593,0.990727,NO,248,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.361275,0.00428493,0.990727 gb1_D266M,gb1_266,gb1,gb1,P06654,0.990727,NO,266,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.261,-4.619,3.358,,,,,,,0.638,,45.54,HAO,-1.59333,0.177985,0.00394694,0.990727 kka2_1:1_G234M,kka2_1:1_234,Kka2,kka2_1:1,P00552,0.99073,NO,234,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-2.9,-4.839,1.939,,0.494,H,A,0.29,-0.29,1.753,,71.59,OOA,-1.86767,0.520039,0.00984449,0.99073 beta-lactamase_39_E119Q,beta-lactamase_39_119,TEM-1,beta-lactamase_39,P62593,0.990732,NO,119,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.412,-2.449,1.037,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.0495842,0.00386966,0.990732 PSD95pdz3_G383I,PSD95pdz3_383,PSD95pdz3,PSD95pdz3,P31016,0.990736,NO,383,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.008,-3.917,2.909,5.17213,,,,,20.5325,,,,HOP,-1.338,0.0758425,0.000233044,0.990736 beta-lactamase_156_E102P,beta-lactamase_156_102,TEM-1,beta-lactamase_156,P62593,0.990749,NO,102,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.118,-3.88,1.762,,0.722,S,B,1.04,1.82,15.721,15.721,73.08,HAH,-1.581,0.111618,0.00486633,0.990749 beta-lactamase_L47M,beta-lactamase_47,TEM-1,beta-lactamase,P62593,0.99075,NO,47,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.876,-2.629,0.753,5.27297,0.007,E,B,1.07,0.2,1.244,,67.83,AHA,-1.639,0.221079,0.00439844,0.99075 beta-lactamase_156_K30D,beta-lactamase_156_30,TEM-1,beta-lactamase_156,P62593,0.990751,NO,30,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-2.307,-3.567,1.26,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.111618,0.00448593,0.990751 beta-lactamase_156_R81L,beta-lactamase_156_81,TEM-1,beta-lactamase_156,P62593,0.990751,NO,81,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.466,-2.766,1.3,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.111618,0.00499763,0.990751 beta-lactamase_39_L197P,beta-lactamase_39_197,TEM-1,beta-lactamase_39,P62593,0.990751,NO,197,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.853,-4.068,3.215,,0.007,S,B,0.55,0.33,1.559,,60.14,HHP,-1.833,0.0495842,0.00144602,0.990751 beta-lactamase_2500_G194Q,beta-lactamase_2500_194,TEM-1,beta-lactamase_2500,P62593,0.990753,NO,194,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.396,-3.925,2.529,,0.276,S,b,0.29,0.36,3.593,,67.83,POA,-1.832,0.361275,0.00392163,0.990753 beta-lactamase_39_M127E,beta-lactamase_39_127,TEM-1,beta-lactamase_39,P62593,0.990753,NO,127,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-2.251,-3.04,0.789,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.0495842,0.00437927,0.990753 beta-lactamase_39_A40I,beta-lactamase_39_40,TEM-1,beta-lactamase_39,P62593,0.990755,NO,40,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.402,-3.742,2.34,,0.155,S,B,0.46,0.21,0.783,,73.78,OHB,-1.40267,0.0495842,0.00490026,0.990755 beta-lactamase_39_P217A,beta-lactamase_39_217,TEM-1,beta-lactamase_39,P62593,0.990758,NO,217,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-2.062,-1.891,-0.171,,0.496,I,A,0.52,-0.33,21.172,21.172,74.48,OOH,-1.64333,0.0495842,0.00463211,0.990758 beta-lactamase_P172L,beta-lactamase_172,TEM-1,beta-lactamase,P62593,0.99076,NO,172,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.998,-2.658,1.66,5.98941,0.639,T,b,1.1,0.24,2.087,,74.48,HOP,-2.03067,0.221079,0.00312594,0.99076 beta-lactamase_625_Q267M,beta-lactamase_625_267,TEM-1,beta-lactamase_625,P62593,0.990763,NO,267,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.213352,0.0102128,0.990763 beta-lactamase_156_A225W,beta-lactamase_156_225,TEM-1,beta-lactamase_156,P62593,0.990764,NO,225,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.845,-5.541,3.696,,1,T,B,0.46,-0.38,11.722,11.722,74.48,OHO,-1.39967,0.111618,0.00465057,0.990764 beta-lactamase_39_Q86W,beta-lactamase_39_86,TEM-1,beta-lactamase_39,P62593,0.990768,NO,86,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.4,-5.489,3.089,,0.696,S,A,0.64,2.38,27.704,27.704,77.62,OPA,-1.61067,0.0495842,0.00450027,0.990768 beta-lactamase_625_R202A,beta-lactamase_625_202,TEM-1,beta-lactamase_625,P62593,0.990768,NO,202,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.292,-2.462,1.17,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.213352,0.00321899,0.990768 beta-lactamase_625_Q267H,beta-lactamase_625_267,TEM-1,beta-lactamase_625,P62593,0.990772,NO,267,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.213352,0.0102128,0.990772 beta-lactamase_625_K144S,beta-lactamase_625_144,TEM-1,beta-lactamase_625,P62593,0.990778,NO,144,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-2.388,-2.51,0.122,,0.863,H,A,2.34,1.27,2.313,,77.62,OBA,-1.904,0.213352,0.00481141,0.990778 beta-lactamase_156_L111H,beta-lactamase_156_111,TEM-1,beta-lactamase_156,P62593,0.990794,NO,111,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.76,-4.922,3.162,,0.328,T,A,0.55,0.93,2.26,,64.34,BHP,-1.884,0.111618,0.00480671,0.990794 kka2_1:2_Y218M,kka2_1:2_218,Kka2,kka2_1:2,P00552,0.990796,NO,218,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-1.438,-4.695,3.257,,0.122,H,A,0.21,-0.69,1.022,,56.06,BHP,-1.17533,0.295029,0.0126098,0.990796 beta-lactamase_156_L47Q,beta-lactamase_156_47,TEM-1,beta-lactamase_156,P62593,0.990799,NO,47,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.876,-3.17,1.294,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.111618,0.00439844,0.990799 kka2_1:1_R122R,kka2_1:1_122,Kka2,kka2_1:1,P00552,0.990804,NO,122,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.175,-2.175,,,0.487,H,A,1.2,0.26,1.356,,71.59,BBH,-1.53833,0.520039,0.00736512,0.990804 WW_domain_M179G,WW_domain_179,Yap65,WW_domain,P46937,0.990804,NO,179,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.541,-3.36,1.819,6.54704,,,,,,,,,AHH,-1.31367,0.153962,0.00400164,0.990804 beta-lactamase_156_E238Y,beta-lactamase_156_238,TEM-1,beta-lactamase_156,P62593,0.990805,NO,238,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.111618,0.00743256,0.990805 beta-lactamase_39_S122C,beta-lactamase_39_122,TEM-1,beta-lactamase_39,P62593,0.990806,NO,122,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.406,-5.091,2.685,,0.352,H,A,0.27,-0.54,2.004,,77.62,OPH,-1.39767,0.0495842,0.00497825,0.990806 beta-lactamase_39_I140N,beta-lactamase_39_140,TEM-1,beta-lactamase_39,P62593,0.99081,NO,140,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.733,-4.2,2.467,,0.128,H,A,0.48,0.41,1.16,,73.08,PHO,-1.48733,0.0495842,0.00597777,0.99081 beta-lactamase_2500_S256A,beta-lactamase_2500_256,TEM-1,beta-lactamase_2500,P62593,0.990812,NO,256,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.361275,0.00710634,0.990812 beta-lactamase_625_H287D,beta-lactamase_625_287,TEM-1,beta-lactamase_625,P62593,0.990814,NO,287,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,,,,,,,,,,,,,BBH,-1.111,0.213352,,0.990814 beta-lactamase_156_A247T,beta-lactamase_156_247,TEM-1,beta-lactamase_156,P62593,0.990818,NO,247,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.111618,0.00611275,0.990818 beta-lactamase_625_G141E,beta-lactamase_625_141,TEM-1,beta-lactamase_625,P62593,0.990823,NO,141,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.828,-2.606,1.778,,0.575,T,l,0.29,-0.28,0.198,,64.69,HOO,-1.08933,0.213352,0.0012419,0.990823 beta-lactamase_625_T269Y,beta-lactamase_625_269,TEM-1,beta-lactamase_625,P62593,0.990825,NO,269,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.213352,0.00950944,0.990825 beta-lactamase_W163Y,beta-lactamase_163,TEM-1,beta-lactamase,P62593,0.990831,NO,163,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-1.843,-3.906,2.063,6.2765,0.467,,B,1.22,-0.5,3.642,,63.99,BHA,-1.269,0.221079,0.00418955,0.990831 beta-lactamase_625_A282Q,beta-lactamase_625_282,TEM-1,beta-lactamase_625,P62593,0.990839,NO,282,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.213352,0.0449821,0.990839 beta-lactamase_2500_E166S,beta-lactamase_2500_166,TEM-1,beta-lactamase_2500,P62593,0.990841,NO,166,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.756,-2.582,0.826,,0.508,G,A,1.04,1.05,2.124,,73.08,OAH,-1.42233,0.361275,0.00512989,0.990841 Pab1_D144K,Pab1_144,Pab1,Pab1,P04147,0.990843,NO,144,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.189,-3.179,1.99,,0.616,H,A,,0.6,,,,HAP,-1.40567,0.175299,0.00121131,0.990843 PSD95pdz3_T385A,PSD95pdz3_385,PSD95pdz3,PSD95pdz3,P31016,0.990846,NO,385,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.533,-2.533,1,5.57157,,,,,23.6871,4.527,,87.71,PPH,-1.56567,0.0758425,0.000545119,0.990846 beta-lactamase_2500_M184I,beta-lactamase_2500_184,TEM-1,beta-lactamase_2500,P62593,0.990847,NO,184,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.593,-2.332,0.739,,,H,A,0.55,-0.87,2.893,,62.94,HHH,-1.41,0.361275,0.00356019,0.990847 beta-lactamase_156_E238I,beta-lactamase_156_238,TEM-1,beta-lactamase_156,P62593,0.990855,NO,238,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.111618,0.00743256,0.990855 beta-lactamase_156_L89T,beta-lactamase_156_89,TEM-1,beta-lactamase_156,P62593,0.990856,NO,89,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.096,-3.474,2.378,,0.168,T,A,0.55,0.63,2.633,,64.34,PHO,-1.75767,0.111618,0.00207068,0.990856 beta-lactamase_156_E56L,beta-lactamase_156_56,TEM-1,beta-lactamase_156,P62593,0.990858,NO,56,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.043,-3.398,1.355,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.111618,0.00238534,0.990858 beta-lactamase_156_I229A,beta-lactamase_156_229,TEM-1,beta-lactamase_156,P62593,0.990858,NO,229,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.267,-3.077,1.81,,0.083,E,B,0.48,-0.76,1.114,,50,HHH,-1.58767,0.111618,0.00477249,0.990858 beta-lactamase_156_P25Y,beta-lactamase_156_25,TEM-1,beta-lactamase_156,P62593,0.990862,NO,25,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.526,-4.327,2.801,,0.624,H,A,0.52,0.14,1.079,,73.08,BOA,-2.15367,0.111618,0.00347571,0.990862 beta-lactamase_2500_N50Q,beta-lactamase_2500_50,TEM-1,beta-lactamase_2500,P62593,0.990866,NO,50,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-2.979,-2.653,-0.326,,0.912,T,A,0.61,1.24,1.581,,77.62,HPP,-2.134,0.361275,0.0047211,0.990866 beta-lactamase_156_S256V,beta-lactamase_156_256,TEM-1,beta-lactamase_156,P62593,0.990872,NO,256,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.111618,0.00710634,0.990872 beta-lactamase_39_R257H,beta-lactamase_39_257,TEM-1,beta-lactamase_39,P62593,0.990876,NO,257,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.0495842,0.00756629,0.990876 beta-lactamase_156_D33A,beta-lactamase_156_33,TEM-1,beta-lactamase_156,P62593,0.990877,NO,33,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.321,-2.241,-0.08,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.111618,0.00435556,0.990877 beta-lactamase_156_A235T,beta-lactamase_156_235,TEM-1,beta-lactamase_156,P62593,0.990878,NO,235,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.266,-2.412,1.146,,0.32,E,B,0.46,-0.86,1.344,,50,OHO,-0.89,0.111618,0.00493474,0.990878 beta-lactamase_156_L38G,beta-lactamase_156_38,TEM-1,beta-lactamase_156,P62593,0.990883,NO,38,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.343,-3.696,2.353,,0.088,H,A,0.55,0.2,13.556,13.556,64.34,PHO,-1.78033,0.111618,0.00373244,0.990883 kka2_1:2_R202H,kka2_1:2_202,Kka2,kka2_1:2,P00552,0.990891,NO,202,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.761,-2.934,1.173,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.295029,0.00696498,0.990891 beta-lactamase_156_I245M,beta-lactamase_156_245,TEM-1,beta-lactamase_156,P62593,0.990892,NO,245,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.111618,0.00391032,0.990892 beta-lactamase_Q86K,beta-lactamase_86,TEM-1,beta-lactamase,P62593,0.990893,NO,86,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.4,-2.554,0.154,5.39897,0.696,S,A,0.12,2.38,2.105,,77.62,OPA,-1.61067,0.221079,0.00450027,0.990893 beta-lactamase_156_N152A,beta-lactamase_156_152,TEM-1,beta-lactamase_156,P62593,0.990895,NO,152,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-2.757,-2.374,-0.383,,0.863,H,A,0.61,0.92,4.038,,77.62,BPH,-2.97,0.111618,0.00471429,0.990895 beta-lactamase_2500_I285V,beta-lactamase_2500_285,TEM-1,beta-lactamase_2500,P62593,0.9909,NO,285,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.361275,0.101555,0.9909 beta-lactamase_L28L,beta-lactamase_28,TEM-1,beta-lactamase,P62593,0.9909,NO,28,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.579,-1.579,,5.42969,0.277,H,A,0.07,-0.16,19.748,19.748,93.01,PHH,-2.11333,0.221079,0.00359321,0.9909 beta-lactamase_39_P165V,beta-lactamase_39_165,TEM-1,beta-lactamase_39,P62593,0.990902,NO,165,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.373,-3.333,1.96,,0.203,T,A,0.52,-0.31,3.907,,73.78,AOA,-1.359,0.0495842,0.00549538,0.990902 beta-lactamase_625_T116C,beta-lactamase_625_116,TEM-1,beta-lactamase_625,P62593,0.990904,NO,116,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.28,-4.831,3.551,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.213352,0.00336175,0.990904 beta-lactamase_156_N98V,beta-lactamase_156_98,TEM-1,beta-lactamase_156,P62593,0.990906,NO,98,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-2.973,-3.696,0.723,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.111618,0.00505389,0.990906 beta-lactamase_2500_R275S,beta-lactamase_2500_275,TEM-1,beta-lactamase_2500,P62593,0.990906,NO,275,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.361275,0.0141984,0.990906 beta-lactamase_625_L223C,beta-lactamase_625_223,TEM-1,beta-lactamase_625,P62593,0.990908,NO,223,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.055,-4.721,3.666,,0.27,,B,0.55,0.09,1.633,,74.48,HHO,-1.35033,0.213352,0.00372793,0.990908 beta-lactamase_625_S201N,beta-lactamase_625_201,TEM-1,beta-lactamase_625,P62593,0.990909,NO,201,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.183,-3.471,2.288,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.213352,0.00198815,0.990909 beta-lactamase_156_G265D,beta-lactamase_156_265,TEM-1,beta-lactamase_156,P62593,0.990913,NO,265,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.111618,0.00811926,0.990913 beta-lactamase_625_L137M,beta-lactamase_625_137,TEM-1,beta-lactamase_625,P62593,0.990915,NO,137,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.03,-2.58,1.55,,,H,A,0.55,-0.38,1.5,,42.31,HHP,-1.58933,0.213352,0.00278599,0.990915 beta-lactamase_625_V157E,beta-lactamase_625_157,TEM-1,beta-lactamase_625,P62593,0.990919,NO,157,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.751,-3.68,1.929,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.213352,0.00506849,0.990919 beta-lactamase_625_H156P,beta-lactamase_625_156,TEM-1,beta-lactamase_625,P62593,0.990922,NO,156,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-3.156,-2.552,-0.604,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.213352,0.00468596,0.990922 beta-lactamase_0_I54M,beta-lactamase_0_54,TEM-1,beta-lactamase_0,P62593,0.990925,NO,54,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-2.838,-3.13,0.292,,0.669,E,B,0.48,-0.14,0.541,,73.78,BHH,-2.337,0.0500837,0.00403589,0.990925 beta-lactamase_625_S283H,beta-lactamase_625_283,TEM-1,beta-lactamase_625,P62593,0.990926,NO,283,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.213352,0.0429138,0.990926 beta-lactamase_39_N173M,beta-lactamase_39_173,TEM-1,beta-lactamase_39,P62593,0.990932,NO,173,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-2.663,-4.901,2.238,,1.044,T,l,0.61,1.25,1.426,,77.62,OPA,-1.46633,0.0495842,0.0033769,0.990932 beta-lactamase_156_H94K,beta-lactamase_156_94,TEM-1,beta-lactamase_156,P62593,0.990933,NO,94,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-2.5,-2.567,0.067,,0.776,,B,0.17,1.24,11.583,11.583,77.62,HBH,-1.872,0.111618,0.00389226,0.990933 beta-lactamase_625_E175G,beta-lactamase_625_175,TEM-1,beta-lactamase_625,P62593,0.990933,NO,175,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.336,-3.483,1.147,,0.551,,A,1.04,1.05,8.527,8.527,77.62,AAB,-1.31233,0.213352,0.00482205,0.990933 beta-lactamase_0_P65R,beta-lactamase_0_65,TEM-1,beta-lactamase_0,P62593,0.990941,NO,65,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.894,-3.951,3.057,,0.098,E,B,0.52,-0.62,0.663,,40.56,HOH,-1.03233,0.0500837,0.00152776,0.990941 beta-lactamase_L150V,beta-lactamase_150,TEM-1,beta-lactamase,P62593,0.990942,NO,150,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.326,-2.348,1.022,5.15566,,H,A,1.75,-0.2,1.615,,62.94,HHB,-1.86167,0.221079,0.00463171,0.990942 beta-lactamase_156_Q203V,beta-lactamase_156_203,TEM-1,beta-lactamase_156,P62593,0.990943,NO,203,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.168,-3.605,1.437,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.111618,0.00631514,0.990943 beta-lactamase_2500_N173L,beta-lactamase_2500_173,TEM-1,beta-lactamase_2500,P62593,0.990943,NO,173,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-2.663,-3.749,1.086,,1.044,T,l,0.61,1.25,1.88,,77.62,OPA,-1.46633,0.361275,0.0033769,0.990943 beta-lactamase_39_G253Y,beta-lactamase_39_253,TEM-1,beta-lactamase_39,P62593,0.990945,NO,253,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.0495842,0.00786358,0.990945 beta-lactamase_156_N98P,beta-lactamase_156_98,TEM-1,beta-lactamase_156,P62593,0.990948,NO,98,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-2.973,-3.946,0.973,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.111618,0.00505389,0.990948 beta-lactamase_2500_A268F,beta-lactamase_2500_268,TEM-1,beta-lactamase_2500,P62593,0.990951,NO,268,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.361275,0.0102525,0.990951 beta-lactamase_39_E175A,beta-lactamase_39_175,TEM-1,beta-lactamase_39,P62593,0.990958,NO,175,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.336,-2.1,-0.236,,0.551,,A,1.04,1.05,3.676,,77.62,AAB,-1.31233,0.0495842,0.00482205,0.990958 beta-lactamase_156_A225R,beta-lactamase_156_225,TEM-1,beta-lactamase_156,P62593,0.990966,NO,225,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.845,-2.864,1.019,,1,T,B,0.46,-0.38,11.722,11.722,74.48,OHO,-1.39967,0.111618,0.00465057,0.990966 beta-lactamase_156_V157F,beta-lactamase_156_157,TEM-1,beta-lactamase_156,P62593,0.990966,NO,157,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.751,-3.968,2.217,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.111618,0.00506849,0.990966 beta-lactamase_39_S283W,beta-lactamase_39_283,TEM-1,beta-lactamase_39,P62593,0.990968,NO,283,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.0495842,0.0429138,0.990968 beta-lactamase_39_M66Y,beta-lactamase_39_66,TEM-1,beta-lactamase_39,P62593,0.990971,NO,66,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.362,-4.034,2.672,,0.013,,A,0.55,-0.7,1.319,,73.08,OHH,-1.49567,0.0495842,0.00412876,0.990971 beta-lactamase_2500_T193W,beta-lactamase_2500_193,TEM-1,beta-lactamase_2500,P62593,0.990974,NO,193,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.914,-5.211,3.297,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.361275,0.00482669,0.990974 beta-lactamase_156_D83C,beta-lactamase_156_83,TEM-1,beta-lactamase_156,P62593,0.990978,NO,83,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.066,-5.147,4.081,,0.354,H,A,0.75,0.22,1.281,,48.95,HAH,-1.34733,0.111618,0.00205968,0.990978 beta-lactamase_156_A40E,beta-lactamase_156_40,TEM-1,beta-lactamase_156,P62593,0.990979,NO,40,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.402,-3.641,2.239,,0.155,S,B,0.46,0.21,1.357,,73.78,OHB,-1.40267,0.111618,0.00490026,0.990979 beta-lactamase_39_I206C,beta-lactamase_39_206,TEM-1,beta-lactamase_39,P62593,0.990979,NO,206,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-2.429,-4.969,2.54,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.0495842,0.00528934,0.990979 beta-lactamase_39_L284M,beta-lactamase_39_284,TEM-1,beta-lactamase_39,P62593,0.99098,NO,284,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.0495842,0.0686156,0.99098 beta-lactamase_625_Q267K,beta-lactamase_625_267,TEM-1,beta-lactamase_625,P62593,0.99098,NO,267,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.213352,0.0102128,0.99098 kka2_1:8_A247E,kka2_1:8_247,Kka2,kka2_1:8,P00552,0.99099,NO,247,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.459,-2.615,0.156,,1.01,S,A,0.46,0.65,18.904,18.904,92.05,HHH,-2.197,0.100394,0.0102428,0.99099 kka2_1:8_A247E,kka2_1:8_247,Kka2,kka2_1:8,P00552,0.99099,NO,247,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.459,-2.615,0.156,,1.01,S,A,0.46,0.65,18.904,18.904,92.05,HHH,-2.197,0.100394,0.0102428,0.99099 kka2_1:8_I196C,kka2_1:8_196,Kka2,kka2_1:8,P00552,0.99099,NO,196,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-2.115,-4.921,2.806,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.100394,0.0107273,0.99099 kka2_1:8_I196C,kka2_1:8_196,Kka2,kka2_1:8,P00552,0.99099,NO,196,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-2.115,-4.921,2.806,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.100394,0.0107273,0.99099 beta-lactamase_625_S80T,beta-lactamase_625_80,TEM-1,beta-lactamase_625,P62593,0.990993,NO,80,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.029,-2.845,0.816,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.213352,0.00565569,0.990993 beta-lactamase_2500_E169K,beta-lactamase_2500_169,TEM-1,beta-lactamase_2500,P62593,0.991001,NO,169,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.23,-3.226,1.996,,0.337,,A,1.04,1,1.806,,73.08,PAH,-1.16533,0.361275,0.00400994,0.991001 beta-lactamase_156_D231P,beta-lactamase_156_231,TEM-1,beta-lactamase_156,P62593,0.991002,NO,231,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.816,-3.68,2.864,,,E,B,0.75,-1.06,2.66,,65.38,HAB,-0.994,0.111618,0.00107395,0.991002 beta-lactamase_156_N98S,beta-lactamase_156_98,TEM-1,beta-lactamase_156,P62593,0.991008,NO,98,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-2.973,-2.34,-0.633,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.111618,0.00505389,0.991008 beta-lactamase_39_N134S,beta-lactamase_39_134,TEM-1,beta-lactamase_39,P62593,0.991008,NO,134,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-0.879,-2.985,2.106,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.0495842,0.000644786,0.991008 beta-lactamase_625_D252S,beta-lactamase_625_252,TEM-1,beta-lactamase_625,P62593,0.99101,NO,252,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.213352,0.00575769,0.99101 beta-lactamase_0_L218H,beta-lactamase_0_218,TEM-1,beta-lactamase_0,P62593,0.991011,NO,218,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.391,-4.744,3.353,,,I,b,0.55,-0.53,28.707,28.707,74.48,OHH,-1.58867,0.0500837,0.00618274,0.991011 beta-lactamase_39_V260L,beta-lactamase_39_260,TEM-1,beta-lactamase_39,P62593,0.991015,NO,260,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.0495842,0.00471757,0.991015 beta-lactamase_E56D,beta-lactamase_56,TEM-1,beta-lactamase,P62593,0.991015,NO,56,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.043,-3.248,1.205,5.65281,0.198,E,B,0.52,0.31,2.022,,72.73,HAP,-1.94033,0.221079,0.00238534,0.991015 beta-lactamase_N50F,beta-lactamase_50,TEM-1,beta-lactamase,P62593,0.991015,NO,50,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-2.979,-4.333,1.354,5.51261,0.912,T,A,1.07,1.24,1.581,,77.62,HPP,-2.134,0.221079,0.0047211,0.991015 beta-lactamase_N50R,beta-lactamase_50,TEM-1,beta-lactamase,P62593,0.991015,NO,50,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-2.979,-3.883,0.904,5.51261,0.912,T,A,1.07,1.24,1.581,,77.62,HPP,-2.134,0.221079,0.0047211,0.991015 beta-lactamase_Q274K,beta-lactamase_274,TEM-1,beta-lactamase,P62593,0.991015,NO,274,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.082,-3.494,1.412,5.6671,0.066,H,A,0.11,-0.27,2.354,,64.69,BPH,-1.931,0.221079,0.0110418,0.991015 beta-lactamase_R92K,beta-lactamase_92,TEM-1,beta-lactamase,P62593,0.991015,NO,92,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.718,-2.258,0.54,5.65832,0.479,E,B,0.91,1.36,3.069,,65.38,BBH,-1.50367,0.221079,0.00429626,0.991015 beta-lactamase_S57K,beta-lactamase_57,TEM-1,beta-lactamase,P62593,0.991015,NO,57,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.918,-3.565,1.647,5.64201,0.352,E,B,0.25,-0.18,1.971,,72.73,APH,-2.29167,0.221079,0.00492804,0.991015 beta-lactamase_T138Y,beta-lactamase_138,TEM-1,beta-lactamase,P62593,0.991015,NO,138,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.506,-4.429,1.923,5.52585,0.662,H,A,0.3,-0.03,30.445,30.445,73.78,HPP,-1.81233,0.221079,0.00487868,0.991015 beta-lactamase_V101D,beta-lactamase_101,TEM-1,beta-lactamase,P62593,0.991015,NO,101,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.295,-2.887,1.592,5.49045,0.342,,B,0.96,0,1.675,,73.08,HHA,-1.54367,0.221079,0.00374492,0.991015 beta-lactamase_625_P224R,beta-lactamase_625_224,TEM-1,beta-lactamase_625,P62593,0.991026,NO,224,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.893,-2.763,1.87,,0.383,,B,0.52,-0.3,1.35,,74.48,HOH,-1.26433,0.213352,0.00189564,0.991026 beta-lactamase_625_L188Y,beta-lactamase_625_188,TEM-1,beta-lactamase_625,P62593,0.991027,NO,188,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.166,-3.998,2.832,,,H,A,0.55,-0.3,2.982,,60.14,PHB,-1.47033,0.213352,0.00295687,0.991027 beta-lactamase_39_V260T,beta-lactamase_39_260,TEM-1,beta-lactamase_39,P62593,0.991029,NO,260,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.0495842,0.00471757,0.991029 beta-lactamase_2500_N152D,beta-lactamase_2500_152,TEM-1,beta-lactamase_2500,P62593,0.991032,NO,152,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-2.757,-3.573,0.816,,0.863,H,A,0.61,0.92,2.061,,77.62,BPH,-2.97,0.361275,0.00471429,0.991032 beta-lactamase_39_L160F,beta-lactamase_39_160,TEM-1,beta-lactamase_39,P62593,0.991039,NO,160,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.977,-3.681,2.704,,0.022,,B,0.55,-0.6,0.895,,44.41,BHA,-0.936,0.0495842,0.00193775,0.991039 beta-lactamase_156_N173I,beta-lactamase_156_173,TEM-1,beta-lactamase_156,P62593,0.991042,NO,173,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-2.663,-4.172,1.509,,1.044,T,l,0.61,1.25,3.718,,77.62,OPA,-1.46633,0.111618,0.0033769,0.991042 beta-lactamase_625_G253Y,beta-lactamase_625_253,TEM-1,beta-lactamase_625,P62593,0.991043,NO,253,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.213352,0.00786358,0.991043 beta-lactamase_39_A230S,beta-lactamase_39_230,TEM-1,beta-lactamase_39,P62593,0.991046,NO,230,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.154,-2.48,1.326,,0.01,E,B,0.46,-1.17,1.171,,50,HHA,-1.079,0.0495842,0.00516841,0.991046 beta-lactamase_625_M180T,beta-lactamase_625_180,TEM-1,beta-lactamase_625,P62593,0.991055,NO,180,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-2.795,-1.278,-1.517,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.213352,0.00552048,0.991055 beta-lactamase_156_P172E,beta-lactamase_156_172,TEM-1,beta-lactamase_156,P62593,0.991057,NO,172,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.998,-3.52,2.522,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.111618,0.00312594,0.991057 Pab1_H134C,Pab1_134,Pab1,Pab1,P04147,0.991057,NO,134,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-1.542,-5.019,3.477,,,,,,,,,,HBO,-1.346,0.175299,0.00116356,0.991057 beta-lactamase_2500_S241G,beta-lactamase_2500_241,TEM-1,beta-lactamase_2500,P62593,0.991061,NO,241,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.361275,0.00452736,0.991061 beta-lactamase_625_A200Y,beta-lactamase_625_200,TEM-1,beta-lactamase_625,P62593,0.991061,NO,200,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.878,-4.399,2.521,,0.757,H,A,0.46,-0.19,12.672,12.672,77.62,HHP,-2.001,0.213352,0.0060056,0.991061 PSD95pdz3_Q374V,PSD95pdz3_374,PSD95pdz3,PSD95pdz3,P31016,0.991063,NO,374,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-1.699,-3.21,1.511,5.38825,,,,,17.3289,,,,APH,-1.47,0.0758425,0.000372298,0.991063 beta-lactamase_156_I140S,beta-lactamase_156_140,TEM-1,beta-lactamase_156,P62593,0.991065,NO,140,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.733,-3.688,1.955,,0.128,H,A,0.48,0.41,1.16,,73.08,PHO,-1.48733,0.111618,0.00597777,0.991065 beta-lactamase_39_A268C,beta-lactamase_39_268,TEM-1,beta-lactamase_39,P62593,0.991065,NO,268,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.0495842,0.0102525,0.991065 gb1_K236A,gb1_236,gb1,gb1,P06654,0.991067,NO,236,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-2.119,-2.064,-0.055,,,,,,,1.083,,45.54,OBP,-1.758,0.177985,0.00255408,0.991067 beta-lactamase_156_L49S,beta-lactamase_156_49,TEM-1,beta-lactamase_156,P62593,0.991073,NO,49,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.897,-2.417,0.52,,0.131,T,A,0.55,0.04,3.112,,64.69,AHP,-1.99233,0.111618,0.00401477,0.991073 beta-lactamase_G216G,beta-lactamase_216,TEM-1,beta-lactamase,P62593,0.991074,NO,216,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.477,-1.477,,4.91694,0.437,I,A,0.23,-0.58,1.718,,74.48,HOO,-1.68067,0.221079,0.00639568,0.991074 beta-lactamase_156_T263M,beta-lactamase_156_263,TEM-1,beta-lactamase_156,P62593,0.991076,NO,263,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.111618,0.0110582,0.991076 beta-lactamase_156_P255S,beta-lactamase_156_255,TEM-1,beta-lactamase_156,P62593,0.991079,NO,255,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.111618,0.00499612,0.991079 beta-lactamase_156_R162K,beta-lactamase_156_162,TEM-1,beta-lactamase_156,P62593,0.99108,NO,162,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.016,-2.948,1.932,,0.124,S,B,1.2,-0.37,7.444,,64.69,ABH,-1.25,0.111618,0.000561334,0.99108 beta-lactamase_156_G216H,beta-lactamase_156_216,TEM-1,beta-lactamase_156,P62593,0.991084,NO,216,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.477,-4.598,3.121,,0.437,I,A,0.29,-0.58,12.464,12.464,74.48,HOO,-1.68067,0.111618,0.00639568,0.991084 beta-lactamase_156_S96W,beta-lactamase_156_96,TEM-1,beta-lactamase_156,P62593,0.991085,NO,96,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.27,-5.497,3.227,,0.368,,b,0.27,0.39,2.838,,73.78,HPP,-2.019,0.111618,0.00551835,0.991085 beta-lactamase_156_E62A,beta-lactamase_156_62,TEM-1,beta-lactamase_156,P62593,0.991086,NO,62,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.193,-2.533,1.34,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.111618,0.00264802,0.991086 beta-lactamase_625_M127V,beta-lactamase_625_127,TEM-1,beta-lactamase_625,P62593,0.991087,NO,127,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-2.251,-2.333,0.082,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.213352,0.00437927,0.991087 beta-lactamase_39_T198G,beta-lactamase_39_198,TEM-1,beta-lactamase_39,P62593,0.991088,NO,198,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.168,-3.295,1.127,,0.489,,B,0.22,-0.13,3.614,,73.78,HPH,-1.98767,0.0495842,0.004311,0.991088 beta-lactamase_156_E56D,beta-lactamase_156_56,TEM-1,beta-lactamase_156,P62593,0.99109,NO,56,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.043,-3.248,1.205,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.111618,0.00238534,0.99109 beta-lactamase_2500_H156D,beta-lactamase_2500_156,TEM-1,beta-lactamase_2500,P62593,0.99109,NO,156,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-3.156,-2.458,-0.698,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.361275,0.00468596,0.99109 beta-lactamase_39_H94S,beta-lactamase_39_94,TEM-1,beta-lactamase_39,P62593,0.99109,NO,94,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-2.5,-3.499,0.999,,0.776,,B,0.17,1.24,11.583,11.583,77.62,HBH,-1.872,0.0495842,0.00389226,0.99109 Pab1_P200V,Pab1_200,Pab1,Pab1,P04147,0.991092,NO,200,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.871,-3.332,1.461,,,,,,,3.877,,80.59,HOO,-1.7005,0.175299,0.00190795,0.991092 beta-lactamase_625_G85M,beta-lactamase_625_85,TEM-1,beta-lactamase_625,P62593,0.991094,NO,85,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.011,-4.877,3.866,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.213352,0.00252173,0.991094 beta-lactamase_156_A34Y,beta-lactamase_156_34,TEM-1,beta-lactamase_156,P62593,0.991095,NO,34,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.059,-4.077,2.018,,,H,A,0.46,-0.54,3.614,,73.78,AHA,-1.74967,0.111618,0.00407913,0.991095 beta-lactamase_39_A123E,beta-lactamase_39_123,TEM-1,beta-lactamase_39,P62593,0.991098,NO,123,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.834,-3.489,2.655,,0.039,H,A,0.46,-0.72,0.705,,41.26,PHH,-1.47367,0.0495842,0.0010157,0.991098 beta-lactamase_2500_A282G,beta-lactamase_2500_282,TEM-1,beta-lactamase_2500,P62593,0.991099,NO,282,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.361275,0.0449821,0.991099 kka2_1:2_G88S,kka2_1:2_88,Kka2,kka2_1:2,P00552,0.991101,NO,88,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.689,-2.938,1.249,,0.54,S,l,0.75,1.51,2.814,,65.53,HOB,-1.718,0.295029,0.00685559,0.991101 beta-lactamase_156_T264Q,beta-lactamase_156_264,TEM-1,beta-lactamase_156,P62593,0.991105,NO,264,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.111618,0.0119399,0.991105 Pab1_E195Q,Pab1_195,Pab1,Pab1,P04147,0.991106,NO,195,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.2,-2.179,0.979,,,,,,,,,,PAH,-1.72467,0.175299,0.000620107,0.991106 beta-lactamase_625_T139R,beta-lactamase_625_139,TEM-1,beta-lactamase_625,P62593,0.991109,NO,139,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.901,-2.238,0.337,,0.216,H,A,0.22,0.39,2.256,,77.62,PPH,-2.04667,0.213352,0.00441837,0.991109 beta-lactamase_625_R239K,beta-lactamase_625_239,TEM-1,beta-lactamase_625,P62593,0.99111,NO,239,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.213352,0.00213852,0.99111 beta-lactamase_156_L38R,beta-lactamase_156_38,TEM-1,beta-lactamase_156,P62593,0.991111,NO,38,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.343,-4.054,2.711,,0.088,H,A,0.55,0.2,13.556,13.556,64.34,PHO,-1.78033,0.111618,0.00373244,0.991111 beta-lactamase_T186T,beta-lactamase_186,TEM-1,beta-lactamase,P62593,0.991116,NO,186,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.522,-2.522,,5.07364,0.396,H,A,0.3,-0.28,2.144,,77.62,HPP,-1.77633,0.221079,0.00485034,0.991116 beta-lactamase_156_I245A,beta-lactamase_156_245,TEM-1,beta-lactamase_156,P62593,0.991117,NO,245,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.068,-3.611,2.543,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.111618,0.00391032,0.991117 beta-lactamase_39_G52N,beta-lactamase_39_52,TEM-1,beta-lactamase_39,P62593,0.991117,NO,52,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.149,-3.58,2.431,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.0495842,0.00340138,0.991117 beta-lactamase_625_M127E,beta-lactamase_625_127,TEM-1,beta-lactamase_625,P62593,0.991117,NO,127,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-2.251,-3.04,0.789,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.213352,0.00437927,0.991117 beta-lactamase_E175R,beta-lactamase_175,TEM-1,beta-lactamase,P62593,0.991117,NO,175,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.336,-3.064,0.728,6.0311,0.551,,A,0.75,1.05,5.316,,77.62,AAB,-1.31233,0.221079,0.00482205,0.991117 PSD95pdz3_N369L,PSD95pdz3_369,PSD95pdz3,PSD95pdz3,P31016,0.991117,NO,369,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-1.572,-3.264,1.692,5.91569,,,,,24.1262,0.44,,87.71,BPH,-1.487,0.0758425,0.000608412,0.991117 beta-lactamase_2500_E61R,beta-lactamase_2500_61,TEM-1,beta-lactamase_2500,P62593,0.991122,NO,61,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.115,-3.845,1.73,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.361275,0.00440955,0.991122 kka2_1:8_R217K,kka2_1:8_217,Kka2,kka2_1:8,P00552,0.991124,NO,217,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.158,-3.143,1.985,,0.252,T,A,0.16,-0.59,1.151,,52.27,ABH,-1.127,0.100394,0.0047191,0.991124 kka2_1:8_R217K,kka2_1:8_217,Kka2,kka2_1:8,P00552,0.991124,NO,217,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.158,-3.143,1.985,,0.252,T,A,0.16,-0.59,1.151,,52.27,ABH,-1.127,0.100394,0.0047191,0.991124 hsp90_E590L,hsp90_590,hsp90,hsp90,P02829,0.991131,NO,590,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.818,-2.511,0,4.65049,0.021,H,A,,0.03,,,,HAO,-3.338,0.368192,0.000222939,0.991131 beta-lactamase_2500_Q37W,beta-lactamase_2500_37,TEM-1,beta-lactamase_2500,P62593,0.991132,NO,37,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.134,-3.439,1.305,,0.613,H,A,0.64,1.98,1.318,,73.08,APH,-2.06967,0.361275,0.00425833,0.991132 beta-lactamase_2500_A34V,beta-lactamase_2500_34,TEM-1,beta-lactamase_2500,P62593,0.991133,NO,34,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.059,-2.227,0.168,,,H,A,0.46,-0.54,2.921,,73.78,AHA,-1.74967,0.361275,0.00407913,0.991133 beta-lactamase_156_P165Y,beta-lactamase_156_165,TEM-1,beta-lactamase_156,P62593,0.991137,NO,165,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.373,-4.331,2.958,,0.203,T,A,0.52,-0.31,3.907,,73.78,AOA,-1.359,0.111618,0.00549538,0.991137 beta-lactamase_39_I45G,beta-lactamase_39_45,TEM-1,beta-lactamase_39,P62593,0.991139,NO,45,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-2.421,-3.565,1.144,,,E,B,0.48,-0.3,2.256,,77.62,HHA,-2.30267,0.0495842,0.00452842,0.991139 kka2_1:8_L165M,kka2_1:8_165,Kka2,kka2_1:8,P00552,0.991142,NO,165,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-2.453,-2.818,0.365,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.100394,0.00801161,0.991142 kka2_1:8_L165M,kka2_1:8_165,Kka2,kka2_1:8,P00552,0.991142,NO,165,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-2.453,-2.818,0.365,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.100394,0.00801161,0.991142 beta-lactamase_625_S57E,beta-lactamase_625_57,TEM-1,beta-lactamase_625,P62593,0.991143,NO,57,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.918,-2.903,0.985,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.213352,0.00492804,0.991143 beta-lactamase_2500_N173D,beta-lactamase_2500_173,TEM-1,beta-lactamase_2500,P62593,0.991145,NO,173,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-2.663,-2.368,-0.295,,1.044,T,l,0.61,1.25,1.88,,77.62,OPA,-1.46633,0.361275,0.0033769,0.991145 beta-lactamase_39_Q88L,beta-lactamase_39_88,TEM-1,beta-lactamase_39,P62593,0.991145,NO,88,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.086,-3.504,1.418,,0.807,,B,0.64,2.03,11.108,11.108,77.62,APH,-1.53433,0.0495842,0.00504167,0.991145 beta-lactamase_2500_R92T,beta-lactamase_2500_92,TEM-1,beta-lactamase_2500,P62593,0.991146,NO,92,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.718,-2.88,1.162,,0.479,E,B,1.2,1.36,3.069,,65.38,BBH,-1.50367,0.361275,0.00429626,0.991146 kka2_1:4_R177R,kka2_1:4_177,Kka2,kka2_1:4,P00552,0.991147,NO,177,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.282,-2.282,,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.168804,0.00768224,0.991147 beta-lactamase_625_I206V,beta-lactamase_625_206,TEM-1,beta-lactamase_625,P62593,0.991152,NO,206,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-2.429,-2.433,0.004,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.213352,0.00528934,0.991152 beta-lactamase_2500_K254G,beta-lactamase_2500_254,TEM-1,beta-lactamase_2500,P62593,0.991156,NO,254,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.361275,0.00369,0.991156 beta-lactamase_39_G90E,beta-lactamase_39_90,TEM-1,beta-lactamase_39,P62593,0.991156,NO,90,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-2.091,-2.175,0.084,,0.598,T,A,0.29,0.32,30.794,30.794,77.62,HOB,-1.52633,0.0495842,0.00490273,0.991156 beta-lactamase_625_W163C,beta-lactamase_625_163,TEM-1,beta-lactamase_625,P62593,0.991157,NO,163,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-1.843,-5.117,3.274,,0.467,,B,0.47,-0.5,5.019,,63.99,BHA,-1.269,0.213352,0.00418955,0.991157 beta-lactamase_0_T147P,beta-lactamase_0_147,TEM-1,beta-lactamase_0,P62593,0.991166,NO,147,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.149,-3.818,2.669,,0.281,H,A,0.22,-0.68,3.487,,64.34,HPH,-1.456,0.0500837,0.00226017,0.991166 beta-lactamase_39_S122Q,beta-lactamase_39_122,TEM-1,beta-lactamase_39,P62593,0.991167,NO,122,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.406,-2.914,0.508,,0.352,H,A,0.27,-0.54,2.004,,77.62,OPH,-1.39767,0.0495842,0.00497825,0.991167 beta-lactamase_156_K32C,beta-lactamase_156_32,TEM-1,beta-lactamase_156,P62593,0.991173,NO,32,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.984,-5.093,3.109,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.111618,0.00401283,0.991173 beta-lactamase_2500_I171K,beta-lactamase_2500_171,TEM-1,beta-lactamase_2500,P62593,0.991178,NO,171,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-2.431,-2.528,0.097,,0.361,,B,0.48,0.53,1.66,,77.62,HHO,-1.55533,0.361275,0.00623355,0.991178 PSD95pdz3_L323F,PSD95pdz3_323,PSD95pdz3,PSD95pdz3,P31016,0.991178,NO,323,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.347,-3.299,1.952,5.12397,,,,,13.8825,,,,OHO,-1.121,0.0758425,0.00104644,0.991178 beta-lactamase_39_T138Y,beta-lactamase_39_138,TEM-1,beta-lactamase_39,P62593,0.991181,NO,138,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.506,-4.429,1.923,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.0495842,0.00487868,0.991181 beta-lactamase_625_E145H,beta-lactamase_625_145,TEM-1,beta-lactamase_625,P62593,0.991183,NO,145,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.357,-4.656,2.299,,0.545,H,A,1.04,0.79,2.64,,77.62,BAH,-2.069,0.213352,0.00553285,0.991183 beta-lactamase_156_W163H,beta-lactamase_156_163,TEM-1,beta-lactamase_156,P62593,0.991185,NO,163,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-1.843,-3.378,1.535,,0.467,,B,0.47,-0.5,15.095,15.095,63.99,BHA,-1.269,0.111618,0.00418955,0.991185 kka2_1:2_S11S,kka2_1:2_11,Kka2,kka2_1:2,P00552,0.991187,NO,11,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.322,-2.322,,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.295029,0.00381691,0.991187 kka2_1:2_Y22S,kka2_1:2_22,Kka2,kka2_1:2,P00552,0.991187,NO,22,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-1.583,-2.891,1.308,,0.122,.,B,0.21,-0.8,1.838,,65.53,OHA,-1.80333,0.295029,0.00598977,0.991187 PSD95pdz3_G322E,PSD95pdz3_322,PSD95pdz3,PSD95pdz3,P31016,0.991187,NO,322,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.008,-3.347,2.339,5.24791,,,,,16.3275,,,,POH,-1.24867,0.0758425,0.00105821,0.991187 beta-lactamase_I93L,beta-lactamase_93,TEM-1,beta-lactamase,P62593,0.991189,NO,93,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.401,-2.05,0.649,5.74695,0.128,E,B,0.77,0.44,1.757,,67.83,BHB,-1.873,0.221079,0.00527066,0.991189 beta-lactamase_625_D271M,beta-lactamase_625_271,TEM-1,beta-lactamase_625,P62593,0.991193,NO,271,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.213352,0.00752082,0.991193 beta-lactamase_156_P105K,beta-lactamase_156_105,TEM-1,beta-lactamase_156,P62593,0.991194,NO,105,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.813,-3.454,2.641,,0.226,T,A,0.52,0.8,1.154,,63.29,POH,-1.01533,0.111618,0.0011981,0.991194 beta-lactamase_39_E279F,beta-lactamase_39_279,TEM-1,beta-lactamase_39,P62593,0.991194,NO,279,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.0495842,0.0192826,0.991194 beta-lactamase_39_L160P,beta-lactamase_39_160,TEM-1,beta-lactamase_39,P62593,0.991199,NO,160,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.977,-4.121,3.144,,0.022,,B,0.55,-0.6,0.895,,44.41,BHA,-0.936,0.0495842,0.00193775,0.991199 beta-lactamase_156_R202K,beta-lactamase_156_202,TEM-1,beta-lactamase_156,P62593,0.991202,NO,202,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.292,-3.005,1.713,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.111618,0.00321899,0.991202 beta-lactamase_0_T131P,beta-lactamase_0_131,TEM-1,beta-lactamase_0,P62593,0.991204,NO,131,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.328,-3.82,2.492,,,H,A,0.22,-0.69,3.306,,67.48,PPH,-1.00867,0.0500837,0.00345886,0.991204 beta-lactamase_156_S122E,beta-lactamase_156_122,TEM-1,beta-lactamase_156,P62593,0.991204,NO,122,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.406,-2.103,-0.303,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.111618,0.00497825,0.991204 beta-lactamase_156_M66I,beta-lactamase_156_66,TEM-1,beta-lactamase_156,P62593,0.991205,NO,66,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.362,-2.521,1.159,,0.013,,A,0.55,-0.7,1.94,,73.08,OHH,-1.49567,0.111618,0.00412876,0.991205 beta-lactamase_0_A34S,beta-lactamase_0_34,TEM-1,beta-lactamase_0,P62593,0.991206,NO,34,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.059,-2.213,0.154,,,H,A,0.46,-0.54,3.998,,73.78,AHA,-1.74967,0.0500837,0.00407913,0.991206 beta-lactamase_625_E169Y,beta-lactamase_625_169,TEM-1,beta-lactamase_625,P62593,0.991211,NO,169,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.23,-4.247,3.017,,0.337,,A,1.04,1,1.806,,73.08,PAH,-1.16533,0.213352,0.00400994,0.991211 beta-lactamase_625_D99W,beta-lactamase_625_99,TEM-1,beta-lactamase_625,P62593,0.991212,NO,99,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.191,-5.462,4.271,,0.402,G,A,0.75,0.36,1.318,,64.69,PAH,-1.794,0.213352,0.00305446,0.991212 beta-lactamase_156_A222Q,beta-lactamase_156_222,TEM-1,beta-lactamase_156,P62593,0.991215,NO,222,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.103,-4.105,2.002,,0.233,H,A,0.46,-0.25,2.461,,77.62,PHH,-1.63733,0.111618,0.00466094,0.991215 beta-lactamase_625_G216E,beta-lactamase_625_216,TEM-1,beta-lactamase_625,P62593,0.991216,NO,216,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.477,-2.451,0.974,,0.437,I,A,0.29,-0.58,1.718,,74.48,HOO,-1.68067,0.213352,0.00639568,0.991216 beta-lactamase_D250M,beta-lactamase_250,TEM-1,beta-lactamase,P62593,0.991218,NO,250,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.335,-4.838,2.503,5.72026,0.89,T,L,0.23,1.53,24.737,24.737,66.08,OAO,-1.85133,0.221079,0.00550899,0.991218 beta-lactamase_625_L38V,beta-lactamase_625_38,TEM-1,beta-lactamase_625,P62593,0.991221,NO,38,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.343,-2.209,0.866,,0.088,H,A,0.55,0.2,1.986,,64.34,PHO,-1.78033,0.213352,0.00373244,0.991221 beta-lactamase_P60T,beta-lactamase_60,TEM-1,beta-lactamase,P62593,0.991224,NO,60,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-2.469,-3.483,1.014,5.51353,0.256,T,A,0.73,-0.56,3.653,,77.62,BOA,-1.97633,0.221079,0.00521318,0.991224 beta-lactamase_39_P105N,beta-lactamase_39_105,TEM-1,beta-lactamase_39,P62593,0.991225,NO,105,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.813,-3.82,3.007,,0.226,T,A,0.52,0.8,1.222,,63.29,POH,-1.01533,0.0495842,0.0011981,0.991225 beta-lactamase_625_D161H,beta-lactamase_625_161,TEM-1,beta-lactamase_625,P62593,0.991225,NO,161,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.891,-4.479,3.588,,0.341,,A,0.75,-0.52,4.655,,61.19,HAB,-0.961333,0.213352,0.000897697,0.991225 beta-lactamase_156_N98A,beta-lactamase_156_98,TEM-1,beta-lactamase_156,P62593,0.991229,NO,98,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-2.973,-2.132,-0.841,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.111618,0.00505389,0.991229 beta-lactamase_156_E169L,beta-lactamase_156_169,TEM-1,beta-lactamase_156,P62593,0.991233,NO,169,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.23,-3.533,2.303,,0.337,,A,1.04,1,3.516,,73.08,PAH,-1.16533,0.111618,0.00400994,0.991233 beta-lactamase_N50A,beta-lactamase_50,TEM-1,beta-lactamase,P62593,0.991236,NO,50,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-2.979,-1.868,-1.111,5.51261,0.912,T,A,1.07,1.24,1.581,,77.62,HPP,-2.134,0.221079,0.0047211,0.991236 beta-lactamase_R189F,beta-lactamase_189,TEM-1,beta-lactamase,P62593,0.991236,NO,189,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.844,-4.275,2.431,5.74877,0.278,H,A,0.68,1.01,1.512,,72.73,HBB,-1.668,0.221079,0.0050699,0.991236 beta-lactamase_2500_Y95W,beta-lactamase_2500_95,TEM-1,beta-lactamase_2500,P62593,0.991237,NO,95,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-1.715,-3.22,1.505,,0.122,,b,0.21,-0.37,2.914,,77.62,BHP,-2.16167,0.361275,0.00479449,0.991237 beta-lactamase_39_R159E,beta-lactamase_39_159,TEM-1,beta-lactamase_39,P62593,0.99124,NO,159,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-0.94,-3.241,2.301,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.0495842,0.00108472,0.99124 beta-lactamase_E56A,beta-lactamase_56,TEM-1,beta-lactamase,P62593,0.991242,NO,56,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.043,-2.078,0.035,5.65281,0.198,E,B,0.52,0.31,2.022,,72.73,HAP,-1.94033,0.221079,0.00238534,0.991242 beta-lactamase_156_C121M,beta-lactamase_156_121,TEM-1,beta-lactamase_156,P62593,0.991247,NO,121,C,M,CM,Special,Hydrophobic,5.07,5.74,0.67,196,121,149,28,108.5,162.9,54.4,-0.953,-4.506,3.553,,,H,A,0.46,-0.81,1.136,,63.29,HOP,-1.46767,0.111618,0.000744322,0.991247 beta-lactamase_625_E119Q,beta-lactamase_625_119,TEM-1,beta-lactamase_625,P62593,0.991247,NO,119,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.412,-2.449,1.037,,0.358,H,A,1.04,0.51,1.034,,63.99,BAH,-1.623,0.213352,0.00386966,0.991247 PSD95pdz3_A382N,PSD95pdz3_382,PSD95pdz3,PSD95pdz3,P31016,0.991248,NO,382,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.307,-3.58,2.273,5.30282,,,,,22.472,,,,PHO,-1.24167,0.0758425,0.000249256,0.991248 beta-lactamase_39_L219C,beta-lactamase_39_219,TEM-1,beta-lactamase_39,P62593,0.991253,NO,219,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.313,-3.103,1.79,,,I,A,0.55,-0.51,19.842,19.842,74.48,HHB,-1.21533,0.0495842,0.00664345,0.991253 beta-lactamase_156_R176V,beta-lactamase_156_176,TEM-1,beta-lactamase_156,P62593,0.991258,NO,176,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-0.863,-3.754,2.891,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.111618,0.00105554,0.991258 beta-lactamase_39_T116H,beta-lactamase_39_116,TEM-1,beta-lactamase_39,P62593,0.99126,NO,116,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.28,-4.615,3.335,,0.115,E,B,0.22,-0.12,1.133,,67.48,HPH,-1.39967,0.0495842,0.00336175,0.99126 beta-lactamase_625_D207I,beta-lactamase_625_207,TEM-1,beta-lactamase_625,P62593,0.991263,NO,207,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.064,-4.165,2.101,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.213352,0.00592942,0.991263 Pab1_A178C,Pab1_178,Pab1,Pab1,P04147,0.991266,NO,178,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.579,-4.586,3.007,,0.019,H,A,0.64,0.64,2.7,,81.63,OHH,-1.61067,0.175299,0.00160192,0.991266 kka2_1:1_G6G,kka2_1:1_6,Kka2,kka2_1:1,P00552,0.991269,NO,6,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.685,-1.685,,,,,,,,1.292,,71.59,AOH,-1.639,0.520039,0.00204693,0.991269 beta-lactamase_625_N168S,beta-lactamase_625_168,TEM-1,beta-lactamase_625,P62593,0.991276,NO,168,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-1.029,-2.37,1.341,,0.113,G,A,0.61,-0.4,1.014,,44.41,HPA,-1.13233,0.213352,0.00288667,0.991276 beta-lactamase_E175S,beta-lactamase_175,TEM-1,beta-lactamase,P62593,0.991276,NO,175,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.336,-2.863,0.527,6.0311,0.551,,A,0.75,1.05,5.316,,77.62,AAB,-1.31233,0.221079,0.00482205,0.991276 beta-lactamase_0_D48K,beta-lactamase_0_48,TEM-1,beta-lactamase_0,P62593,0.991279,NO,48,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.101,-3.448,2.347,,0.189,E,B,0.75,0.21,17.825,17.825,50.35,HAH,-1.62467,0.0500837,0.0027273,0.991279 beta-lactamase_P172T,beta-lactamase_172,TEM-1,beta-lactamase,P62593,0.99128,NO,172,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.998,-3.409,2.411,5.98941,0.639,T,b,1.1,0.24,2.087,,74.48,HOP,-2.03067,0.221079,0.00312594,0.99128 beta-lactamase_0_T187A,beta-lactamase_0_187,TEM-1,beta-lactamase_0,P62593,0.991286,NO,187,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.401,-3.072,1.671,,0.007,H,A,0.22,-1.19,3.259,,67.48,PPH,-1.69633,0.0500837,0.00491782,0.991286 beta-lactamase_2500_Q86L,beta-lactamase_2500_86,TEM-1,beta-lactamase_2500,P62593,0.991288,NO,86,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.4,-2.558,0.158,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.361275,0.00450027,0.991288 WW_domain_I193T,WW_domain_193,Yap65,WW_domain,P46937,0.991289,NO,193,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.993,-3.409,1.416,6.15906,,,,,,1.833,,83.33,BHA,-1.756,0.153962,0.00587613,0.991289 beta-lactamase_2500_A282F,beta-lactamase_2500_282,TEM-1,beta-lactamase_2500,P62593,0.991295,NO,282,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.361275,0.0449821,0.991295 beta-lactamase_625_T269Q,beta-lactamase_625_269,TEM-1,beta-lactamase_625,P62593,0.991296,NO,269,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.213352,0.00950944,0.991296 beta-lactamase_39_A185C,beta-lactamase_39_185,TEM-1,beta-lactamase_39,P62593,0.991299,NO,185,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.406,-4.699,3.293,,,H,A,0.46,-1.02,2.68,,65.03,HHP,-1.84033,0.0495842,0.00467449,0.991299 beta-lactamase_2500_E108Q,beta-lactamase_2500_108,TEM-1,beta-lactamase_2500,P62593,0.9913,NO,108,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.46,-2.893,1.433,,0.572,G,A,1.04,1.87,1.147,,72.73,PAB,-1.437,0.361275,0.00413372,0.9913 beta-lactamase_156_H110N,beta-lactamase_156_110,TEM-1,beta-lactamase_156,P62593,0.991302,NO,110,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-1.706,-3.626,1.92,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.111618,0.00441499,0.991302 beta-lactamase_39_S283A,beta-lactamase_39_283,TEM-1,beta-lactamase_39,P62593,0.991307,NO,283,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.0495842,0.0429138,0.991307 beta-lactamase_156_V157A,beta-lactamase_156_157,TEM-1,beta-lactamase_156,P62593,0.991308,NO,157,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.751,-2.656,0.905,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.111618,0.00506849,0.991308 beta-lactamase_39_L218I,beta-lactamase_39_218,TEM-1,beta-lactamase_39,P62593,0.991312,NO,218,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.391,-3.447,2.056,,,I,b,0.55,-0.53,2.038,,74.48,OHH,-1.58867,0.0495842,0.00618274,0.991312 beta-lactamase_625_E108Q,beta-lactamase_625_108,TEM-1,beta-lactamase_625,P62593,0.991315,NO,108,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.46,-2.893,1.433,,0.572,G,A,1.04,1.87,20.151,20.151,72.73,PAB,-1.437,0.213352,0.00413372,0.991315 beta-lactamase_Q86E,beta-lactamase_86,TEM-1,beta-lactamase,P62593,0.991315,NO,86,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.4,-2.379,-0.021,5.39897,0.696,S,A,0.12,2.38,2.105,,77.62,OPA,-1.61067,0.221079,0.00450027,0.991315 beta-lactamase_156_R275W,beta-lactamase_156_275,TEM-1,beta-lactamase_156,P62593,0.991318,NO,275,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.111618,0.0141984,0.991318 beta-lactamase_156_T178V,beta-lactamase_156_178,TEM-1,beta-lactamase_156,P62593,0.991321,NO,178,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-0.791,-3.079,2.288,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.111618,0.000684366,0.991321 beta-lactamase_156_R189V,beta-lactamase_156_189,TEM-1,beta-lactamase_156,P62593,0.991322,NO,189,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.844,-3.783,1.939,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.111618,0.0050699,0.991322 beta-lactamase_625_M184I,beta-lactamase_625_184,TEM-1,beta-lactamase_625,P62593,0.991324,NO,184,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.593,-2.332,0.739,,,H,A,0.55,-0.87,2.765,,62.94,HHH,-1.41,0.213352,0.00356019,0.991324 beta-lactamase_156_P172W,beta-lactamase_156_172,TEM-1,beta-lactamase_156,P62593,0.991327,NO,172,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.998,-5.528,4.53,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.111618,0.00312594,0.991327 beta-lactamase_156_R162T,beta-lactamase_156_162,TEM-1,beta-lactamase_156,P62593,0.991329,NO,162,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.016,-3.471,2.455,,0.124,S,B,1.2,-0.37,7.444,,64.69,ABH,-1.25,0.111618,0.000561334,0.991329 beta-lactamase_156_W163C,beta-lactamase_156_163,TEM-1,beta-lactamase_156,P62593,0.991332,NO,163,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-1.843,-5.117,3.274,,0.467,,B,0.47,-0.5,15.095,15.095,63.99,BHA,-1.269,0.111618,0.00418955,0.991332 beta-lactamase_625_G85E,beta-lactamase_625_85,TEM-1,beta-lactamase_625,P62593,0.991333,NO,85,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.011,-3.408,2.397,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.213352,0.00252173,0.991333 beta-lactamase_156_C75G,beta-lactamase_156_75,TEM-1,beta-lactamase_156,P62593,0.991334,NO,75,C,G,CG,Special,Special,5.07,3.29388,-1.77612,159,121,75,-46,108.5,60.1,-48.4,-1.245,-2.515,1.27,,,H,A,0.46,-0.87,0.876,,50,HOO,-1.24333,0.111618,0.0034616,0.991334 beta-lactamase_625_G43S,beta-lactamase_625_43,TEM-1,beta-lactamase_625,P62593,0.991334,NO,43,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.62,-3.161,2.541,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.213352,0.00120151,0.991334 beta-lactamase_625_H156G,beta-lactamase_625_156,TEM-1,beta-lactamase_625,P62593,0.991336,NO,156,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-3.156,-2.688,-0.468,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.213352,0.00468596,0.991336 beta-lactamase_39_E145H,beta-lactamase_39_145,TEM-1,beta-lactamase_39,P62593,0.991338,NO,145,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.357,-4.656,2.299,,0.545,H,A,1.04,0.79,1.199,,77.62,BAH,-2.069,0.0495842,0.00553285,0.991338 beta-lactamase_156_K144P,beta-lactamase_156_144,TEM-1,beta-lactamase_156,P62593,0.991339,NO,144,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-2.388,-2.633,0.245,,0.863,H,A,2.34,1.27,2.073,,77.62,OBA,-1.904,0.111618,0.00481141,0.991339 beta-lactamase_625_E169Q,beta-lactamase_625_169,TEM-1,beta-lactamase_625,P62593,0.991339,NO,169,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.23,-2.523,1.293,,0.337,,A,1.04,1,1.806,,73.08,PAH,-1.16533,0.213352,0.00400994,0.991339 beta-lactamase_625_P224Q,beta-lactamase_625_224,TEM-1,beta-lactamase_625,P62593,0.991347,NO,224,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.893,-3.868,2.975,,0.383,,B,0.52,-0.3,1.35,,74.48,HOH,-1.26433,0.213352,0.00189564,0.991347 beta-lactamase_625_P172N,beta-lactamase_625_172,TEM-1,beta-lactamase_625,P62593,0.991348,NO,172,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.998,-3.875,2.877,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.213352,0.00312594,0.991348 beta-lactamase_156_V101Y,beta-lactamase_156_101,TEM-1,beta-lactamase_156,P62593,0.991349,NO,101,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.295,-4.116,2.821,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.111618,0.00374492,0.991349 beta-lactamase_156_P143N,beta-lactamase_156_143,TEM-1,beta-lactamase_156,P62593,0.991351,NO,143,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.967,-3.954,2.987,,0.075,H,A,0.52,-0.37,0.479,,66.78,OOB,-1.354,0.111618,0.00114551,0.991351 beta-lactamase_2500_H151D,beta-lactamase_2500_151,TEM-1,beta-lactamase_2500,P62593,0.991351,NO,151,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-2.96,-3.624,0.664,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.361275,0.00216946,0.991351 beta-lactamase_0_P217W,beta-lactamase_0_217,TEM-1,beta-lactamase_0,P62593,0.991354,NO,217,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-2.062,-5.565,3.503,,0.496,I,A,0.52,-0.33,1.087,,74.48,OOH,-1.64333,0.0500837,0.00463211,0.991354 PSD95pdz3_T387I,PSD95pdz3_387,PSD95pdz3,PSD95pdz3,P31016,0.991354,NO,387,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.391,-3.242,1.851,5.20757,,,,,18.8043,,,,HPH,-1.49533,0.0758425,0.000167911,0.991354 beta-lactamase_156_I54D,beta-lactamase_156_54,TEM-1,beta-lactamase_156,P62593,0.991356,NO,54,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-2.838,-3.732,0.894,,0.669,E,B,0.48,-0.14,0.541,,73.78,BHH,-2.337,0.111618,0.00403589,0.991356 beta-lactamase_156_A278V,beta-lactamase_156_278,TEM-1,beta-lactamase_156,P62593,0.991361,NO,278,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.111618,0.0310297,0.991361 beta-lactamase_N50H,beta-lactamase_50,TEM-1,beta-lactamase,P62593,0.991365,NO,50,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-2.979,-3.33,0.351,5.51261,0.912,T,A,1.07,1.24,1.581,,77.62,HPP,-2.134,0.221079,0.0047211,0.991365 beta-lactamase_V29C,beta-lactamase_29,TEM-1,beta-lactamase,P62593,0.991365,NO,29,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-2.856,-5.117,2.261,5.58481,0.733,H,A,0.23,-0.78,1.287,,93.01,HHB,-2.24733,0.221079,0.00318969,0.991365 beta-lactamase_625_S51Q,beta-lactamase_625_51,TEM-1,beta-lactamase_625,P62593,0.99137,NO,51,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.526,-3.91,2.384,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.213352,0.00504821,0.99137 beta-lactamase_625_S283E,beta-lactamase_625_283,TEM-1,beta-lactamase_625,P62593,0.991371,NO,283,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.213352,0.0429138,0.991371 beta-lactamase_39_G265I,beta-lactamase_39_265,TEM-1,beta-lactamase_39,P62593,0.991375,NO,265,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.0495842,0.00811926,0.991375 beta-lactamase_2500_A182I,beta-lactamase_2500_182,TEM-1,beta-lactamase_2500,P62593,0.991387,NO,182,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.777,-3.851,2.074,,0.136,H,A,0.46,-0.66,2.032,,93.01,OHH,-1.27367,0.361275,0.00559099,0.991387 beta-lactamase_156_E119Q,beta-lactamase_156_119,TEM-1,beta-lactamase_156,P62593,0.9914,NO,119,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.412,-2.449,1.037,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.111618,0.00386966,0.9914 beta-lactamase_R118L,beta-lactamase_118,TEM-1,beta-lactamase,P62593,0.991403,NO,118,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.413,-2.872,0.459,5.8227,0.457,H,A,0.68,1.39,2.144,,77.62,HBA,-1.785,0.221079,0.00538794,0.991403 PSD95pdz3_I341V,PSD95pdz3_341,PSD95pdz3,PSD95pdz3,P31016,0.991403,NO,341,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.63,-2.085,0.455,5.73946,,,,,10.3187,,,,HHH,-1.50033,0.0758425,0.000824087,0.991403 beta-lactamase_156_T139P,beta-lactamase_156_139,TEM-1,beta-lactamase_156,P62593,0.991405,NO,139,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.901,-3.919,2.018,,0.216,H,A,0.22,0.39,16.34,16.34,77.62,PPH,-2.04667,0.111618,0.00441837,0.991405 beta-lactamase_156_P172F,beta-lactamase_156_172,TEM-1,beta-lactamase_156,P62593,0.991407,NO,172,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.998,-4.371,3.373,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.111618,0.00312594,0.991407 gb1_T244S,gb1_244,gb1,gb1,P06654,0.991407,NO,244,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.637,-3.028,1.391,,,,,,,0.202,,11.83,PPA,-1.92567,0.177985,0.00222755,0.991407 beta-lactamase_39_S104C,beta-lactamase_39_104,TEM-1,beta-lactamase_39,P62593,0.99142,NO,104,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.015,-2.945,1.93,,0.04,,b,0.27,0.57,4.02,,63.29,HPO,-1.05267,0.0495842,0.00218083,0.99142 beta-lactamase_39_Q88A,beta-lactamase_39_88,TEM-1,beta-lactamase_39,P62593,0.991422,NO,88,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.086,-2.75,0.664,,0.807,,B,0.64,2.03,11.108,11.108,77.62,APH,-1.53433,0.0495842,0.00504167,0.991422 Pab1_D160F,Pab1_160,Pab1,Pab1,P04147,0.991423,NO,160,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.985,-4.109,3.124,,0.396,B,B,,1.12,,,,PAA,-1.30133,0.175299,0.000311977,0.991423 beta-lactamase_156_I229V,beta-lactamase_156_229,TEM-1,beta-lactamase_156,P62593,0.991425,NO,229,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.267,-1.684,0.417,,0.083,E,B,0.48,-0.76,1.114,,50,HHH,-1.58767,0.111618,0.00477249,0.991425 beta-lactamase_39_N134Y,beta-lactamase_39_134,TEM-1,beta-lactamase_39,P62593,0.991425,NO,134,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-0.879,-4.188,3.309,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.0495842,0.000644786,0.991425 PSD95pdz3_K393D,PSD95pdz3_393,PSD95pdz3,PSD95pdz3,P31016,0.991428,NO,393,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.416,-3.15,1.734,5.42682,,,,,22.0122,,,,HBO,-1.4265,0.0758425,0.000879298,0.991428 beta-lactamase_39_L205A,beta-lactamase_39_205,TEM-1,beta-lactamase_39,P62593,0.991429,NO,205,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.922,-3.132,2.21,,,H,A,0.55,-0.46,0.846,,42.31,PHH,-1.57767,0.0495842,0.00255802,0.991429 beta-lactamase_39_L248T,beta-lactamase_39_248,TEM-1,beta-lactamase_39,P62593,0.991431,NO,248,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.0495842,0.00428493,0.991431 beta-lactamase_0_G39S,beta-lactamase_0_39,TEM-1,beta-lactamase_0,P62593,0.991432,NO,39,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.864,-2.342,0.478,,0.701,T,L,0.29,0.47,4.111,,77.62,HOH,-1.53633,0.0500837,0.00487611,0.991432 beta-lactamase_625_A282E,beta-lactamase_625_282,TEM-1,beta-lactamase_625,P62593,0.991433,NO,282,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.213352,0.0449821,0.991433 PSD95pdz3_R354Y,PSD95pdz3_354,PSD95pdz3,PSD95pdz3,P31016,0.991435,NO,354,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.582,-3.844,2.262,6.21887,,,,,23.7791,,,,HBB,-1.44833,0.0758425,0.000650924,0.991435 beta-lactamase_625_V214R,beta-lactamase_625_214,TEM-1,beta-lactamase_625,P62593,0.991442,NO,214,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.299,-4.047,2.748,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.213352,0.00628442,0.991442 PSD95pdz3_G333A,PSD95pdz3_333,PSD95pdz3,PSD95pdz3,P31016,0.991443,NO,333,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.008,-2.534,1.526,5.09445,,,,,48.755,,,,AOA,-1.22533,0.0758425,0.00092544,0.991443 beta-lactamase_625_P172G,beta-lactamase_625_172,TEM-1,beta-lactamase_625,P62593,0.991448,NO,172,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.998,-3.35,2.352,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.213352,0.00312594,0.991448 beta-lactamase_R220R,beta-lactamase_220,TEM-1,beta-lactamase,P62593,0.991452,NO,220,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-0.942,-0.942,,5.65995,0.295,I,A,0.68,-0.76,2.164,,74.48,HBP,-1.33633,0.221079,0.00232421,0.991452 beta-lactamase_156_T263Q,beta-lactamase_156_263,TEM-1,beta-lactamase_156,P62593,0.991457,NO,263,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.111618,0.0110582,0.991457 beta-lactamase_156_D99V,beta-lactamase_156_99,TEM-1,beta-lactamase_156,P62593,0.991458,NO,99,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.191,-3.648,2.457,,0.402,G,A,0.75,0.36,3.529,,64.69,PAH,-1.794,0.111618,0.00305446,0.991458 beta-lactamase_39_A200P,beta-lactamase_39_200,TEM-1,beta-lactamase_39,P62593,0.991459,NO,200,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.878,-2.581,0.703,,0.757,H,A,0.46,-0.19,1.54,,77.62,HHP,-2.001,0.0495842,0.0060056,0.991459 beta-lactamase_625_D113L,beta-lactamase_625_113,TEM-1,beta-lactamase_625,P62593,0.991461,NO,113,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.829,-3.651,1.822,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.213352,0.00474112,0.991461 beta-lactamase_0_L218V,beta-lactamase_0_218,TEM-1,beta-lactamase_0,P62593,0.991463,NO,218,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.391,-3.3,1.909,,,I,b,0.55,-0.53,28.707,28.707,74.48,OHH,-1.58867,0.0500837,0.00618274,0.991463 beta-lactamase_156_Q276A,beta-lactamase_156_276,TEM-1,beta-lactamase_156,P62593,0.991472,NO,276,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-1.144,-3.872,2.728,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.111618,0.0191712,0.991472 beta-lactamase_39_K30E,beta-lactamase_39_30,TEM-1,beta-lactamase_39,P62593,0.991474,NO,30,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-2.307,-2.686,0.379,,0.142,H,A,2.34,-0.65,6.717,,93.01,HBH,-2.32833,0.0495842,0.00448593,0.991474 kka2_1:2_D118H,kka2_1:2_118,Kka2,kka2_1:2,P00552,0.991475,NO,118,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.07,-3.064,0.994,,0.61,H,A,0.75,-0.05,2.237,,64.39,HAH,-1.32367,0.295029,0.0067852,0.991475 kka2_1:8_T28W,kka2_1:8_28,Kka2,kka2_1:8,P00552,0.991479,NO,28,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.883,-5.518,3.635,,0.353,S,B,0.22,2.02,18.114,18.114,63.64,PPH,-1.74467,0.100394,0.00743084,0.991479 kka2_1:8_T28W,kka2_1:8_28,Kka2,kka2_1:8,P00552,0.991479,NO,28,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.883,-5.518,3.635,,0.353,S,B,0.22,2.02,18.114,18.114,63.64,PPH,-1.74467,0.100394,0.00743084,0.991479 beta-lactamase_A266V,beta-lactamase_266,TEM-1,beta-lactamase,P62593,0.991484,NO,266,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.369,-2.326,0.957,5.02057,0.175,S,B,0.52,0.07,1.832,,64.34,PHP,-2.08567,0.221079,0.0140785,0.991484 beta-lactamase_L223L,beta-lactamase_223,TEM-1,beta-lactamase,P62593,0.991484,NO,223,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.055,-1.055,,5.42318,0.27,,B,1.3,0.09,1.511,,74.48,HHO,-1.35033,0.221079,0.00372793,0.991484 beta-lactamase_2500_D271E,beta-lactamase_2500_271,TEM-1,beta-lactamase_2500,P62593,0.991487,NO,271,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.361275,0.00752082,0.991487 beta-lactamase_39_P65T,beta-lactamase_39_65,TEM-1,beta-lactamase_39,P62593,0.991487,NO,65,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.894,-3.44,2.546,,0.098,E,B,0.52,-0.62,0.623,,40.56,HOH,-1.03233,0.0495842,0.00152776,0.991487 beta-lactamase_A225A,beta-lactamase_225,TEM-1,beta-lactamase,P62593,0.991487,NO,225,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.845,-1.845,,6.5181,1,T,B,0.58,-0.38,4.077,,74.48,OHO,-1.39967,0.221079,0.00465057,0.991487 beta-lactamase_625_G253T,beta-lactamase_625_253,TEM-1,beta-lactamase_625,P62593,0.991495,NO,253,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.213352,0.00786358,0.991495 beta-lactamase_156_L111P,beta-lactamase_156_111,TEM-1,beta-lactamase_156,P62593,0.991496,NO,111,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.76,-4.076,2.316,,0.328,T,A,0.55,0.93,2.26,,64.34,BHP,-1.884,0.111618,0.00480671,0.991496 beta-lactamase_156_S80V,beta-lactamase_156_80,TEM-1,beta-lactamase_156,P62593,0.991497,NO,80,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.029,-2.695,0.666,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.111618,0.00565569,0.991497 beta-lactamase_156_K190N,beta-lactamase_156_190,TEM-1,beta-lactamase_156,P62593,0.991498,NO,190,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.994,-2.601,0.607,,0.371,H,A,2.34,0.16,1.513,,77.62,BBH,-1.64167,0.111618,0.00574527,0.991498 beta-lactamase_156_E46V,beta-lactamase_156_46,TEM-1,beta-lactamase_156,P62593,0.991499,NO,46,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.94,-1.834,-0.106,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.111618,0.00427568,0.991499 beta-lactamase_156_M184I,beta-lactamase_156_184,TEM-1,beta-lactamase_156,P62593,0.991499,NO,184,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.593,-2.332,0.739,,,H,A,0.55,-0.87,1.671,,62.94,HHH,-1.41,0.111618,0.00356019,0.991499 beta-lactamase_39_E119S,beta-lactamase_39_119,TEM-1,beta-lactamase_39,P62593,0.9915,NO,119,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.412,-2.681,1.269,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.0495842,0.00386966,0.9915 kka2_1:2_E231V,kka2_1:2_231,Kka2,kka2_1:2,P00552,0.9915,NO,231,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.002,-2.912,0.91,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.295029,0.00732383,0.9915 beta-lactamase_625_D99H,beta-lactamase_625_99,TEM-1,beta-lactamase_625,P62593,0.991506,NO,99,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.191,-3.065,1.874,,0.402,G,A,0.75,0.36,1.318,,64.69,PAH,-1.794,0.213352,0.00305446,0.991506 beta-lactamase_156_N274G,beta-lactamase_156_274,TEM-1,beta-lactamase_156,P62593,0.991508,NO,274,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.111618,0.0110418,0.991508 beta-lactamase_A124A,beta-lactamase_124,TEM-1,beta-lactamase,P62593,0.991508,NO,124,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.181,-1.181,,4.58507,,H,A,0.58,-0.9,2.273,,64.34,HHH,-1.152,0.221079,0.00481399,0.991508 beta-lactamase_A211K,beta-lactamase_211,TEM-1,beta-lactamase,P62593,0.991508,NO,211,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.896,-3.538,1.642,5.54662,0.369,T,A,0.52,-0.69,2.061,,77.62,AHA,-1.94633,0.221079,0.00648183,0.991508 beta-lactamase_G90Y,beta-lactamase_90,TEM-1,beta-lactamase,P62593,0.991508,NO,90,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-2.091,-4.355,2.264,5.51991,0.598,T,A,0.23,0.32,1.791,,77.62,HOB,-1.52633,0.221079,0.00490273,0.991508 beta-lactamase_2500_V157H,beta-lactamase_2500_157,TEM-1,beta-lactamase_2500,P62593,0.991515,NO,157,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.751,-3.319,1.568,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.361275,0.00506849,0.991515 beta-lactamase_156_E56K,beta-lactamase_156_56,TEM-1,beta-lactamase_156,P62593,0.991516,NO,56,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.043,-3.327,1.284,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.111618,0.00238534,0.991516 beta-lactamase_39_L160G,beta-lactamase_39_160,TEM-1,beta-lactamase_39,P62593,0.991524,NO,160,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.977,-3.824,2.847,,0.022,,B,0.55,-0.6,0.895,,44.41,BHA,-0.936,0.0495842,0.00193775,0.991524 beta-lactamase_39_L160V,beta-lactamase_39_160,TEM-1,beta-lactamase_39,P62593,0.991529,NO,160,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.977,-2.271,1.294,,0.022,,B,0.55,-0.6,0.895,,44.41,BHA,-0.936,0.0495842,0.00193775,0.991529 beta-lactamase_39_H110N,beta-lactamase_39_110,TEM-1,beta-lactamase_39,P62593,0.99153,NO,110,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-1.706,-3.626,1.92,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.0495842,0.00441499,0.99153 beta-lactamase_39_R242E,beta-lactamase_39_242,TEM-1,beta-lactamase_39,P62593,0.991536,NO,242,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.0495842,0.00452879,0.991536 beta-lactamase_156_L167Q,beta-lactamase_156_167,TEM-1,beta-lactamase_156,P62593,0.991539,NO,167,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.138,-4.038,2.9,,0.015,G,A,0.55,-0.63,0.4,,64.69,AHP,-1.30767,0.111618,0.00303566,0.991539 beta-lactamase_625_K144L,beta-lactamase_625_144,TEM-1,beta-lactamase_625,P62593,0.991541,NO,144,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-2.388,-3.577,1.189,,0.863,H,A,2.34,1.27,2.313,,77.62,OBA,-1.904,0.213352,0.00481141,0.991541 beta-lactamase_156_K254S,beta-lactamase_156_254,TEM-1,beta-lactamase_156,P62593,0.991546,NO,254,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-2.126,-3.446,1.32,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.111618,0.00369,0.991546 beta-lactamase_156_A148T,beta-lactamase_156_148,TEM-1,beta-lactamase_156,P62593,0.991547,NO,148,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.757,-2.508,0.751,,0.379,H,A,0.46,-0.55,3.551,,72.73,PHH,-1.40167,0.111618,0.00547053,0.991547 beta-lactamase_156_T158S,beta-lactamase_156_158,TEM-1,beta-lactamase_156,P62593,0.991549,NO,158,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.116,-1.795,0.679,,0.036,,B,0.22,-0.85,3.771,,69.58,HPB,-1.269,0.111618,0.00341825,0.991549 beta-lactamase_625_F228R,beta-lactamase_625_228,TEM-1,beta-lactamase_625,P62593,0.991549,NO,228,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-2.342,-2.044,-0.298,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.213352,0.0046669,0.991549 beta-lactamase_39_R273Q,beta-lactamase_39_273,TEM-1,beta-lactamase_39,P62593,0.99155,NO,273,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.314,-2.364,0.05,,0.564,H,A,1.2,1.57,2.163,,73.78,ABP,-1.841,0.0495842,0.0077952,0.99155 beta-lactamase_S128S,beta-lactamase_128,TEM-1,beta-lactamase,P62593,0.991552,NO,128,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-0.84,-0.84,,5.37153,0.08,,L,0.73,-0.32,,,,HPA,-1.30233,0.221079,0.00071483,0.991552 beta-lactamase_156_T107V,beta-lactamase_156_107,TEM-1,beta-lactamase_156,P62593,0.991555,NO,107,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.117,-3.226,2.109,,,G,A,0.22,-0.06,0.341,,67.83,HPA,-1.265,0.111618,0.00239347,0.991555 beta-lactamase_156_A34G,beta-lactamase_156_34,TEM-1,beta-lactamase_156,P62593,0.99156,NO,34,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.059,-3.469,1.41,,,H,A,0.46,-0.54,3.614,,73.78,AHA,-1.74967,0.111618,0.00407913,0.99156 beta-lactamase_156_I258C,beta-lactamase_156_258,TEM-1,beta-lactamase_156,P62593,0.991562,NO,258,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.111618,0.007931,0.991562 beta-lactamase_625_A225M,beta-lactamase_625_225,TEM-1,beta-lactamase_625,P62593,0.991563,NO,225,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.845,-4.778,2.933,,1,T,B,0.46,-0.38,9.874,9.874,74.48,OHO,-1.39967,0.213352,0.00465057,0.991563 beta-lactamase_156_N152F,beta-lactamase_156_152,TEM-1,beta-lactamase_156,P62593,0.991568,NO,152,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-2.757,-4.363,1.606,,0.863,H,A,0.61,0.92,4.038,,77.62,BPH,-2.97,0.111618,0.00471429,0.991568 beta-lactamase_39_A77G,beta-lactamase_39_77,TEM-1,beta-lactamase_39,P62593,0.991571,NO,77,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.234,-2.31,1.076,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.0495842,0.00282362,0.991571 beta-lactamase_156_I125M,beta-lactamase_156_125,TEM-1,beta-lactamase_156,P62593,0.991574,NO,125,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.441,-2.597,1.156,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.111618,0.00383964,0.991574 beta-lactamase_625_S221I,beta-lactamase_625_221,TEM-1,beta-lactamase_625,P62593,0.991574,NO,221,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.754,-3.812,2.058,,0.624,H,A,0.27,-0.2,1.495,,74.48,BPH,-1.59967,0.213352,0.0046094,0.991574 gb1_K276W,gb1_276,gb1,gb1,P06654,0.991577,NO,276,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.456,-5.162,3.706,,,,,,,0.236,,12.72,PBP,-1.65133,0.177985,0.00620493,0.991577 beta-lactamase_625_R63P,beta-lactamase_625_63,TEM-1,beta-lactamase_625,P62593,0.991584,NO,63,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-0.943,-3.929,2.986,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.213352,0.00126938,0.991584 beta-lactamase_39_L167F,beta-lactamase_39_167,TEM-1,beta-lactamase_39,P62593,0.991587,NO,167,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.138,-3.813,2.675,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.0495842,0.00303566,0.991587 beta-lactamase_156_E169K,beta-lactamase_156_169,TEM-1,beta-lactamase_156,P62593,0.991593,NO,169,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.23,-3.226,1.996,,0.337,,A,1.04,1,3.516,,73.08,PAH,-1.16533,0.111618,0.00400994,0.991593 beta-lactamase_2500_P25D,beta-lactamase_2500_25,TEM-1,beta-lactamase_2500,P62593,0.991594,NO,25,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.526,-2.562,1.036,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.361275,0.00347571,0.991594 beta-lactamase_39_L49K,beta-lactamase_39_49,TEM-1,beta-lactamase_39,P62593,0.991594,NO,49,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.897,-3.583,1.686,,0.131,T,A,0.55,0.04,13.838,13.838,64.69,AHP,-1.99233,0.0495842,0.00401477,0.991594 beta-lactamase_625_G154E,beta-lactamase_625_154,TEM-1,beta-lactamase_625,P62593,0.9916,NO,154,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.823,-3.512,2.689,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.213352,0.00180205,0.9916 beta-lactamase_39_N274E,beta-lactamase_39_274,TEM-1,beta-lactamase_39,P62593,0.991601,NO,274,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.0495842,0.0110418,0.991601 beta-lactamase_2500_T126S,beta-lactamase_2500_126,TEM-1,beta-lactamase_2500,P62593,0.991602,NO,126,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.122,-2.464,1.342,,0.05,H,A,0.22,-0.05,0.817,,44.41,HPH,-1.60467,0.361275,0.00244552,0.991602 beta-lactamase_156_L205M,beta-lactamase_156_205,TEM-1,beta-lactamase_156,P62593,0.991604,NO,205,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.922,-3.889,2.967,,,H,A,0.55,-0.46,0.678,,42.31,PHH,-1.57767,0.111618,0.00255802,0.991604 beta-lactamase_2500_P25M,beta-lactamase_2500_25,TEM-1,beta-lactamase_2500,P62593,0.991605,NO,25,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.526,-4.708,3.182,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.361275,0.00347571,0.991605 beta-lactamase_39_D231M,beta-lactamase_39_231,TEM-1,beta-lactamase_39,P62593,0.991605,NO,231,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.816,-4.927,4.111,,,E,B,0.75,-1.06,0.462,,65.38,HAB,-0.994,0.0495842,0.00107395,0.991605 beta-lactamase_156_L150W,beta-lactamase_156_150,TEM-1,beta-lactamase_156,P62593,0.991606,NO,150,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.326,-5.247,3.921,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.111618,0.00463171,0.991606 beta-lactamase_39_R176P,beta-lactamase_39_176,TEM-1,beta-lactamase_39,P62593,0.991609,NO,176,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-0.863,-3.88,3.017,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.0495842,0.00105554,0.991609 beta-lactamase_39_L49E,beta-lactamase_39_49,TEM-1,beta-lactamase_39,P62593,0.99161,NO,49,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.897,-3.608,1.711,,0.131,T,A,0.55,0.04,13.838,13.838,64.69,AHP,-1.99233,0.0495842,0.00401477,0.99161 beta-lactamase_39_V72A,beta-lactamase_39_72,TEM-1,beta-lactamase_39,P62593,0.991613,NO,72,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.658,-1.729,0.071,,,H,A,0.44,-1.03,1.92,,65.73,BHH,-1.32167,0.0495842,0.00501194,0.991613 Pab1_N162S,Pab1_162,Pab1,Pab1,P04147,0.991615,NO,162,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-2.313,-2.638,0.325,,0.681,T,A,,1.12,,,,APO,-1.532,0.175299,0.0030719,0.991615 beta-lactamase_625_I229L,beta-lactamase_625_229,TEM-1,beta-lactamase_625,P62593,0.991619,NO,229,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.267,-2.225,0.958,,0.083,E,B,0.48,-0.76,1.69,,50,HHH,-1.58767,0.213352,0.00477249,0.991619 Pab1_D151N,Pab1_151,Pab1,Pab1,P04147,0.991621,NO,151,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.399,-2.017,-0.382,,,,,,,,,,OAH,-1.51767,0.175299,0.00228155,0.991621 beta-lactamase_625_A268Q,beta-lactamase_625_268,TEM-1,beta-lactamase_625,P62593,0.991635,NO,268,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.213352,0.0102525,0.991635 beta-lactamase_2500_E169T,beta-lactamase_2500_169,TEM-1,beta-lactamase_2500,P62593,0.991641,NO,169,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.23,-2.43,1.2,,0.337,,A,1.04,1,1.806,,73.08,PAH,-1.16533,0.361275,0.00400994,0.991641 beta-lactamase_156_R275V,beta-lactamase_156_275,TEM-1,beta-lactamase_156,P62593,0.991644,NO,275,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.111618,0.0141984,0.991644 beta-lactamase_156_V42A,beta-lactamase_156_42,TEM-1,beta-lactamase_156,P62593,0.991646,NO,42,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.564,-2.554,0.99,,0.017,E,B,0.44,-0.51,2.576,,63.99,BHO,-1.042,0.111618,0.00404515,0.991646 beta-lactamase_156_T107S,beta-lactamase_156_107,TEM-1,beta-lactamase_156,P62593,0.99165,NO,107,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.117,-1.871,0.754,,,G,A,0.22,-0.06,0.341,,67.83,HPA,-1.265,0.111618,0.00239347,0.99165 beta-lactamase_2500_P25Q,beta-lactamase_2500_25,TEM-1,beta-lactamase_2500,P62593,0.99165,NO,25,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.526,-2.522,0.996,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.361275,0.00347571,0.99165 beta-lactamase_39_I54E,beta-lactamase_39_54,TEM-1,beta-lactamase_39,P62593,0.991653,NO,54,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-2.838,-2.58,-0.258,,0.669,E,B,0.48,-0.14,1.349,,73.78,BHH,-2.337,0.0495842,0.00403589,0.991653 beta-lactamase_625_D271R,beta-lactamase_625_271,TEM-1,beta-lactamase_625,P62593,0.991657,NO,271,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.249,-3.747,2.498,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.213352,0.00752082,0.991657 beta-lactamase_39_E175C,beta-lactamase_39_175,TEM-1,beta-lactamase_39,P62593,0.991658,NO,175,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.336,-5.076,2.74,,0.551,,A,1.04,1.05,3.676,,77.62,AAB,-1.31233,0.0495842,0.00482205,0.991658 beta-lactamase_156_D33R,beta-lactamase_156_33,TEM-1,beta-lactamase_156,P62593,0.991659,NO,33,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.321,-2.617,0.296,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.111618,0.00435556,0.991659 beta-lactamase_625_R63V,beta-lactamase_625_63,TEM-1,beta-lactamase_625,P62593,0.991662,NO,63,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-0.943,-3.626,2.683,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.213352,0.00126938,0.991662 beta-lactamase_625_P165K,beta-lactamase_625_165,TEM-1,beta-lactamase_625,P62593,0.991668,NO,165,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.373,-3.528,2.155,,0.203,T,A,0.52,-0.31,0.414,,73.78,AOA,-1.359,0.213352,0.00549538,0.991668 beta-lactamase_625_C75S,beta-lactamase_625_75,TEM-1,beta-lactamase_625,P62593,0.991669,NO,75,C,S,CS,Special,Polar,5.07,5.68,0.61,112,121,105,-16,108.5,89,-19.5,-1.245,-2.597,1.352,,,H,A,0.46,-0.87,2.141,,50,HOO,-1.24333,0.213352,0.0034616,0.991669 beta-lactamase_39_Q276D,beta-lactamase_39_276,TEM-1,beta-lactamase_39,P62593,0.991676,NO,276,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.0495842,0.0191712,0.991676 beta-lactamase_2500_T139Q,beta-lactamase_2500_139,TEM-1,beta-lactamase_2500,P62593,0.991677,NO,139,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.901,-2.8,0.899,,0.216,H,A,0.22,0.39,2.256,,77.62,PPH,-2.04667,0.361275,0.00441837,0.991677 beta-lactamase_39_G226P,beta-lactamase_39_226,TEM-1,beta-lactamase_39,P62593,0.991677,NO,226,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.461,-3.96,2.499,,0.701,T,l,0.29,-0.25,23.034,23.034,74.48,HOH,-1.42933,0.0495842,0.00665294,0.991677 beta-lactamase_156_L196D,beta-lactamase_156_196,TEM-1,beta-lactamase_156,P62593,0.991683,NO,196,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-2.478,-3.862,1.384,,0.518,S,A,0.55,1.35,7.897,,77.62,AHH,-1.839,0.111618,0.00512144,0.991683 beta-lactamase_156_H24S,beta-lactamase_156_24,TEM-1,beta-lactamase_156,P62593,0.991684,NO,24,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-2.481,-1.903,-0.578,,,,,,,2.708,,93.01,OBO,-2.0035,0.111618,0.00238894,0.991684 beta-lactamase_156_S266L,beta-lactamase_156_266,TEM-1,beta-lactamase_156,P62593,0.991684,NO,266,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.111618,0.0140785,0.991684 beta-lactamase_39_V78S,beta-lactamase_39_78,TEM-1,beta-lactamase_39,P62593,0.991692,NO,78,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.459,-3.701,2.242,,,H,A,0.44,-0.47,1.132,,63.64,HHH,-1.17833,0.0495842,0.00492501,0.991692 beta-lactamase_39_G52T,beta-lactamase_39_52,TEM-1,beta-lactamase_39,P62593,0.991696,NO,52,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.149,-3.586,2.437,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.0495842,0.00340138,0.991696 beta-lactamase_39_G226M,beta-lactamase_39_226,TEM-1,beta-lactamase_39,P62593,0.991698,NO,226,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.461,-4.924,3.463,,0.701,T,l,0.29,-0.25,23.034,23.034,74.48,HOH,-1.42933,0.0495842,0.00665294,0.991698 beta-lactamase_39_L136S,beta-lactamase_39_136,TEM-1,beta-lactamase_39,P62593,0.991698,NO,136,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.232,-3.705,2.473,,,H,A,0.55,-0.34,0.336,,48.95,HHH,-1.088,0.0495842,0.00442304,0.991698 beta-lactamase_39_N50Y,beta-lactamase_39_50,TEM-1,beta-lactamase_39,P62593,0.991702,NO,50,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-2.979,-4.3,1.321,,0.912,T,A,0.61,1.24,10.736,,77.62,HPP,-2.134,0.0495842,0.0047211,0.991702 beta-lactamase_625_L47T,beta-lactamase_625_47,TEM-1,beta-lactamase_625,P62593,0.991702,NO,47,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.876,-2.727,0.851,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.213352,0.00439844,0.991702 beta-lactamase_625_D207Y,beta-lactamase_625_207,TEM-1,beta-lactamase_625,P62593,0.991714,NO,207,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.064,-4.317,2.253,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.213352,0.00592942,0.991714 beta-lactamase_156_I45E,beta-lactamase_156_45,TEM-1,beta-lactamase_156,P62593,0.991717,NO,45,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-2.421,-3.737,1.316,,,E,B,0.48,-0.3,2.256,,77.62,HHA,-2.30267,0.111618,0.00452842,0.991717 beta-lactamase_156_G154Q,beta-lactamase_156_154,TEM-1,beta-lactamase_156,P62593,0.991723,NO,154,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.823,-4.083,3.26,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.111618,0.00180205,0.991723 beta-lactamase_39_Q37V,beta-lactamase_39_37,TEM-1,beta-lactamase_39,P62593,0.991723,NO,37,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.134,-3.664,1.53,,0.613,H,A,0.64,1.98,22.282,22.282,73.08,APH,-2.06967,0.0495842,0.00425833,0.991723 beta-lactamase_156_R176L,beta-lactamase_156_176,TEM-1,beta-lactamase_156,P62593,0.991726,NO,176,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-0.863,-3.358,2.495,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.111618,0.00105554,0.991726 beta-lactamase_156_S233P,beta-lactamase_156_233,TEM-1,beta-lactamase_156,P62593,0.991727,NO,233,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.886,-2.778,0.892,,0.016,E,B,0.27,-1.01,4.111,,77.62,BPO,-1.17267,0.111618,0.00311415,0.991727 beta-lactamase_K30K,beta-lactamase_30,TEM-1,beta-lactamase,P62593,0.991727,NO,30,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-2.307,-2.307,,5.30605,0.142,H,A,1.82,-0.65,2.434,,93.01,HBH,-2.32833,0.221079,0.00448593,0.991727 beta-lactamase_625_W163V,beta-lactamase_625_163,TEM-1,beta-lactamase_625,P62593,0.991729,NO,163,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-1.843,-3.617,1.774,,0.467,,B,0.47,-0.5,5.019,,63.99,BHA,-1.269,0.213352,0.00418955,0.991729 beta-lactamase_0_R176N,beta-lactamase_0_176,TEM-1,beta-lactamase_0,P62593,0.991731,NO,176,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-0.863,-3.448,2.585,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.0500837,0.00105554,0.991731 beta-lactamase_39_Q97Y,beta-lactamase_39_97,TEM-1,beta-lactamase_39,P62593,0.991739,NO,97,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.072,-4.35,2.278,,0.823,G,A,0.64,2.42,4.457,,77.62,PPP,-2.43833,0.0495842,0.0045116,0.991739 beta-lactamase_156_Q203D,beta-lactamase_156_203,TEM-1,beta-lactamase_156,P62593,0.991741,NO,203,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.168,-2.512,0.344,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.111618,0.00631514,0.991741 beta-lactamase_39_A200D,beta-lactamase_39_200,TEM-1,beta-lactamase_39,P62593,0.991744,NO,200,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.878,-2.929,1.051,,0.757,H,A,0.46,-0.19,1.54,,77.62,HHP,-2.001,0.0495842,0.0060056,0.991744 gb1_T251N,gb1_251,gb1,gb1,P06654,0.991746,NO,251,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.794,-3.444,1.65,,,,,,,3.514,3.514,37.28,HPH,-1.56067,0.177985,0.00232932,0.991746 gb1_T251V,gb1_251,gb1,gb1,P06654,0.991746,NO,251,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.794,-2.101,0.307,,,,,,,3.514,3.514,37.28,HPH,-1.56067,0.177985,0.00232932,0.991746 beta-lactamase_39_A247F,beta-lactamase_39_247,TEM-1,beta-lactamase_39,P62593,0.991749,NO,247,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.0495842,0.00611275,0.991749 beta-lactamase_39_C121M,beta-lactamase_39_121,TEM-1,beta-lactamase_39,P62593,0.991749,NO,121,C,M,CM,Special,Hydrophobic,5.07,5.74,0.67,196,121,149,28,108.5,162.9,54.4,-0.953,-4.506,3.553,,,H,A,0.46,-0.81,7.644,,63.29,HOP,-1.46767,0.0495842,0.000744322,0.991749 beta-lactamase_R271L,beta-lactamase_271,TEM-1,beta-lactamase,P62593,0.991749,NO,271,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.249,-2.185,0.936,5.24516,0.085,H,A,1.67,-0.05,0.474,,63.99,ABP,-1.36633,0.221079,0.00752082,0.991749 kka2_1:1_A247Q,kka2_1:1_247,Kka2,kka2_1:1,P00552,0.991752,NO,247,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.459,-3.224,0.765,,1.01,S,A,0.46,0.65,7.731,7.731,92.05,HHH,-2.197,0.520039,0.0102428,0.991752 beta-lactamase_39_K53P,beta-lactamase_39_53,TEM-1,beta-lactamase_39,P62593,0.991753,NO,53,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-2.313,-3.069,0.756,,0.589,,B,2.34,1.15,15.633,15.633,77.62,OBH,-2.1,0.0495842,0.00383383,0.991753 beta-lactamase_L188V,beta-lactamase_188,TEM-1,beta-lactamase,P62593,0.991753,NO,188,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.166,-3.017,1.851,5.55434,,H,A,1.07,-0.3,1.574,,60.14,PHB,-1.47033,0.221079,0.00295687,0.991753 beta-lactamase_156_H151A,beta-lactamase_156_151,TEM-1,beta-lactamase_156,P62593,0.991756,NO,151,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-2.96,-3.11,0.15,,0.594,H,A,0.17,0.1,1.401,,77.62,HBP,-2.34767,0.111618,0.00216946,0.991756 beta-lactamase_39_T264V,beta-lactamase_39_264,TEM-1,beta-lactamase_39,P62593,0.991758,NO,264,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.0495842,0.0119399,0.991758 beta-lactamase_39_A40M,beta-lactamase_39_40,TEM-1,beta-lactamase_39,P62593,0.99176,NO,40,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.402,-4.684,3.282,,0.155,S,B,0.46,0.21,0.783,,73.78,OHB,-1.40267,0.0495842,0.00490026,0.99176 beta-lactamase_156_I45H,beta-lactamase_156_45,TEM-1,beta-lactamase_156,P62593,0.991762,NO,45,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-2.421,-3.408,0.987,,,E,B,0.48,-0.3,2.256,,77.62,HHA,-2.30267,0.111618,0.00452842,0.991762 beta-lactamase_625_H94T,beta-lactamase_625_94,TEM-1,beta-lactamase_625,P62593,0.991764,NO,94,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-2.5,-2.6,0.1,,0.776,,B,0.17,1.24,19.42,19.42,77.62,HBH,-1.872,0.213352,0.00389226,0.991764 beta-lactamase_39_H156A,beta-lactamase_39_156,TEM-1,beta-lactamase_39,P62593,0.991766,NO,156,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-3.156,-2.83,-0.326,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.0495842,0.00468596,0.991766 beta-lactamase_0_L111W,beta-lactamase_0_111,TEM-1,beta-lactamase_0,P62593,0.991775,NO,111,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.76,-5.305,3.545,,0.328,T,A,0.55,0.93,1.966,,64.34,BHP,-1.884,0.0500837,0.00480671,0.991775 beta-lactamase_S240G,beta-lactamase_240,TEM-1,beta-lactamase,P62593,0.991775,NO,240,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.537,-2.475,0.938,4.75024,,,B,0.74,-0.74,0.357,,65.38,OPB,-1.263,0.221079,0.00591201,0.991775 beta-lactamase_156_Q267C,beta-lactamase_156_267,TEM-1,beta-lactamase_156,P62593,0.991781,NO,267,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.111618,0.0102128,0.991781 beta-lactamase_2500_E145A,beta-lactamase_2500_145,TEM-1,beta-lactamase_2500,P62593,0.991783,NO,145,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.357,-1.901,-0.456,,0.545,H,A,1.04,0.79,2.124,,77.62,BAH,-2.069,0.361275,0.00553285,0.991783 beta-lactamase_156_N168V,beta-lactamase_156_168,TEM-1,beta-lactamase_156,P62593,0.991785,NO,168,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-1.029,-3.632,2.603,,0.113,G,A,0.61,-0.4,1.014,,44.41,HPA,-1.13233,0.111618,0.00288667,0.991785 beta-lactamase_2500_T193Q,beta-lactamase_2500_193,TEM-1,beta-lactamase_2500,P62593,0.991791,NO,193,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.914,-4.169,2.255,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.361275,0.00482669,0.991791 beta-lactamase_156_Q267S,beta-lactamase_156_267,TEM-1,beta-lactamase_156,P62593,0.991795,NO,267,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.111618,0.0102128,0.991795 beta-lactamase_V214V,beta-lactamase_214,TEM-1,beta-lactamase,P62593,0.991805,NO,214,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.299,-1.299,,5.74008,0.375,S,A,1.19,-0.44,1.899,,74.48,BHH,-1.53733,0.221079,0.00628442,0.991805 beta-lactamase_156_D99W,beta-lactamase_156_99,TEM-1,beta-lactamase_156,P62593,0.991809,NO,99,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.191,-5.462,4.271,,0.402,G,A,0.75,0.36,3.529,,64.69,PAH,-1.794,0.111618,0.00305446,0.991809 beta-lactamase_39_G154A,beta-lactamase_39_154,TEM-1,beta-lactamase_39,P62593,0.991811,NO,154,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.823,-2.356,1.533,,0.54,T,l,0.29,-0.56,1.151,,64.69,HOA,-1.635,0.0495842,0.00180205,0.991811 beta-lactamase_0_R91H,beta-lactamase_0_91,TEM-1,beta-lactamase_0,P62593,0.991816,NO,91,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.392,-4.422,3.03,,0.444,,B,1.2,0.96,4.557,,50.35,OBB,-1.73367,0.0500837,0.00380226,0.991816 beta-lactamase_156_S96D,beta-lactamase_156_96,TEM-1,beta-lactamase_156,P62593,0.991818,NO,96,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.27,-3.641,1.371,,0.368,,b,0.27,0.39,2.838,,73.78,HPP,-2.019,0.111618,0.00551835,0.991818 beta-lactamase_625_I244V,beta-lactamase_625_244,TEM-1,beta-lactamase_625,P62593,0.99182,NO,244,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.555,-1.239,-0.316,,,E,B,0.48,-0.84,2.061,,77.62,OHH,-1.385,0.213352,0.00605379,0.99182 beta-lactamase_39_A77I,beta-lactamase_39_77,TEM-1,beta-lactamase_39,P62593,0.991821,NO,77,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.234,-3.583,2.349,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.0495842,0.00282362,0.991821 beta-lactamase_625_G90V,beta-lactamase_625_90,TEM-1,beta-lactamase_625,P62593,0.991825,NO,90,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-2.091,-3.033,0.942,,0.598,T,A,0.29,0.32,0.319,,77.62,HOB,-1.52633,0.213352,0.00490273,0.991825 beta-lactamase_625_M270E,beta-lactamase_625_270,TEM-1,beta-lactamase_625,P62593,0.991825,NO,270,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.723,-4.709,2.986,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.213352,0.00767762,0.991825 beta-lactamase_156_T263H,beta-lactamase_156_263,TEM-1,beta-lactamase_156,P62593,0.991828,NO,263,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.111618,0.0110582,0.991828 beta-lactamase_156_E169P,beta-lactamase_156_169,TEM-1,beta-lactamase_156,P62593,0.991829,NO,169,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.23,-3.768,2.538,,0.337,,A,1.04,1,3.516,,73.08,PAH,-1.16533,0.111618,0.00400994,0.991829 beta-lactamase_39_S57H,beta-lactamase_39_57,TEM-1,beta-lactamase_39,P62593,0.991829,NO,57,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.918,-3.329,1.411,,0.352,E,B,0.27,-0.18,2.3,,72.73,APH,-2.29167,0.0495842,0.00492804,0.991829 beta-lactamase_625_R92S,beta-lactamase_625_92,TEM-1,beta-lactamase_625,P62593,0.99183,NO,92,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.718,-3.47,1.752,,0.479,E,B,1.2,1.36,3.069,,65.38,BBH,-1.50367,0.213352,0.00429626,0.99183 beta-lactamase_625_L199G,beta-lactamase_625_199,TEM-1,beta-lactamase_625,P62593,0.991837,NO,199,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-2.942,-2.663,-0.279,,0.832,H,A,0.55,0.42,1.552,,77.62,PHH,-2.32933,0.213352,0.0048649,0.991837 beta-lactamase_39_L111C,beta-lactamase_39_111,TEM-1,beta-lactamase_39,P62593,0.991838,NO,111,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.76,-4.796,3.036,,0.328,T,A,0.55,0.93,4.334,,64.34,BHP,-1.884,0.0495842,0.00480671,0.991838 beta-lactamase_625_E145N,beta-lactamase_625_145,TEM-1,beta-lactamase_625,P62593,0.991839,NO,145,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.357,-3.655,1.298,,0.545,H,A,1.04,0.79,2.64,,77.62,BAH,-2.069,0.213352,0.00553285,0.991839 beta-lactamase_156_N50R,beta-lactamase_156_50,TEM-1,beta-lactamase_156,P62593,0.991842,NO,50,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-2.979,-3.883,0.904,,0.912,T,A,0.61,1.24,13.295,13.295,77.62,HPP,-2.134,0.111618,0.0047211,0.991842 beta-lactamase_156_E175R,beta-lactamase_156_175,TEM-1,beta-lactamase_156,P62593,0.991849,NO,175,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.336,-3.064,0.728,,0.551,,A,1.04,1.05,2.334,,77.62,AAB,-1.31233,0.111618,0.00482205,0.991849 beta-lactamase_E175K,beta-lactamase_175,TEM-1,beta-lactamase,P62593,0.99185,NO,175,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.336,-2.673,0.337,6.0311,0.551,,A,0.75,1.05,5.316,,77.62,AAB,-1.31233,0.221079,0.00482205,0.99185 beta-lactamase_E270C,beta-lactamase_270,TEM-1,beta-lactamase,P62593,0.99185,NO,270,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.723,-5.106,3.383,5.33196,0.422,H,A,0.52,1.15,1.745,,64.34,AAB,-1.70933,0.221079,0.00767762,0.99185 beta-lactamase_N98G,beta-lactamase_98,TEM-1,beta-lactamase,P62593,0.99185,NO,98,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-2.973,-3.401,0.428,6.59973,0.963,G,A,1.07,1.35,1.332,,77.62,PPA,-2.07867,0.221079,0.00505389,0.99185 beta-lactamase_S2M,beta-lactamase_2,TEM-1,beta-lactamase,P62593,0.99185,NO,2,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.942,-4.179,2.237,,,,,,,2.36,,65.38,HPH,-2.02767,0.221079,0.00227352,0.99185 beta-lactamase_625_E169S,beta-lactamase_625_169,TEM-1,beta-lactamase_625,P62593,0.991852,NO,169,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.23,-2.21,0.98,,0.337,,A,1.04,1,1.806,,73.08,PAH,-1.16533,0.213352,0.00400994,0.991852 beta-lactamase_625_P165S,beta-lactamase_625_165,TEM-1,beta-lactamase_625,P62593,0.991853,NO,165,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.373,-3.19,1.817,,0.203,T,A,0.52,-0.31,0.414,,73.78,AOA,-1.359,0.213352,0.00549538,0.991853 beta-lactamase_0_E279M,beta-lactamase_0_279,TEM-1,beta-lactamase_0,P62593,0.991854,NO,279,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.0500837,0.0192826,0.991854 beta-lactamase_625_V42C,beta-lactamase_625_42,TEM-1,beta-lactamase_625,P62593,0.991855,NO,42,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.564,-4.789,3.225,,0.017,E,B,0.44,-0.51,2.576,,63.99,BHO,-1.042,0.213352,0.00404515,0.991855 Pab1_G169G,Pab1_169,Pab1,Pab1,P04147,0.991858,NO,169,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.809,-0.809,,,,E,b,0.35,0.03,,,,HOH,-1.11567,0.175299,0.000302434,0.991858 beta-lactamase_156_A222V,beta-lactamase_156_222,TEM-1,beta-lactamase_156,P62593,0.991861,NO,222,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.103,-1.973,-0.13,,0.233,H,A,0.46,-0.25,2.461,,77.62,PHH,-1.63733,0.111618,0.00466094,0.991861 beta-lactamase_2500_K286E,beta-lactamase_2500_286,TEM-1,beta-lactamase_2500,P62593,0.991867,NO,286,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.361275,,0.991867 beta-lactamase_156_N152I,beta-lactamase_156_152,TEM-1,beta-lactamase_156,P62593,0.99187,NO,152,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-2.757,-3.192,0.435,,0.863,H,A,0.61,0.92,4.038,,77.62,BPH,-2.97,0.111618,0.00471429,0.99187 beta-lactamase_156_A282M,beta-lactamase_156_282,TEM-1,beta-lactamase_156,P62593,0.991871,NO,282,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.111618,0.0449821,0.991871 beta-lactamase_156_K53H,beta-lactamase_156_53,TEM-1,beta-lactamase_156,P62593,0.991872,NO,53,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-2.313,-4.67,2.357,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.111618,0.00383383,0.991872 beta-lactamase_0_F64P,beta-lactamase_0_64,TEM-1,beta-lactamase_0,P62593,0.991875,NO,64,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-0.841,-4.33,3.489,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.0500837,0.000947691,0.991875 beta-lactamase_625_Q88I,beta-lactamase_625_88,TEM-1,beta-lactamase_625,P62593,0.991876,NO,88,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.086,-3.166,1.08,,0.807,,B,0.64,2.03,1.84,,77.62,APH,-1.53433,0.213352,0.00504167,0.991876 beta-lactamase_39_R239F,beta-lactamase_39_239,TEM-1,beta-lactamase_39,P62593,0.991877,NO,239,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.0495842,0.00213852,0.991877 beta-lactamase_39_H24T,beta-lactamase_39_24,TEM-1,beta-lactamase_39,P62593,0.991879,NO,24,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-2.481,-2.645,0.164,,,,,,,2.708,,93.01,OBO,-2.0035,0.0495842,0.00238894,0.991879 beta-lactamase_156_A148H,beta-lactamase_156_148,TEM-1,beta-lactamase_156,P62593,0.991886,NO,148,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.757,-3.344,1.587,,0.379,H,A,0.46,-0.55,3.551,,72.73,PHH,-1.40167,0.111618,0.00547053,0.991886 beta-lactamase_2500_R257K,beta-lactamase_2500_257,TEM-1,beta-lactamase_2500,P62593,0.991888,NO,257,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.361275,0.00756629,0.991888 beta-lactamase_625_L199V,beta-lactamase_625_199,TEM-1,beta-lactamase_625,P62593,0.991892,NO,199,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-2.942,-2.773,-0.169,,0.832,H,A,0.55,0.42,1.552,,77.62,PHH,-2.32933,0.213352,0.0048649,0.991892 beta-lactamase_156_I54G,beta-lactamase_156_54,TEM-1,beta-lactamase_156,P62593,0.991895,NO,54,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-2.838,-3.612,0.774,,0.669,E,B,0.48,-0.14,0.541,,73.78,BHH,-2.337,0.111618,0.00403589,0.991895 beta-lactamase_39_P250K,beta-lactamase_39_250,TEM-1,beta-lactamase_39,P62593,0.991899,NO,250,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.0495842,0.00550899,0.991899 beta-lactamase_39_P217V,beta-lactamase_39_217,TEM-1,beta-lactamase_39,P62593,0.991907,NO,217,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-2.062,-3.65,1.588,,0.496,I,A,0.52,-0.33,21.172,21.172,74.48,OOH,-1.64333,0.0495842,0.00463211,0.991907 beta-lactamase_156_L199Q,beta-lactamase_156_199,TEM-1,beta-lactamase_156,P62593,0.991908,NO,199,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-2.942,-3.22,0.278,,0.832,H,A,0.55,0.42,1.552,,77.62,PHH,-2.32933,0.111618,0.0048649,0.991908 Pab1_K164K,Pab1_164,Pab1,Pab1,P04147,0.991912,NO,164,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-2.298,-2.298,,,,,,,,,,,OBP,-1.41767,0.175299,0.00255241,0.991912 gb1_K276D,gb1_276,gb1,gb1,P06654,0.991916,NO,276,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.456,-3.399,1.943,,,,,,,0.236,,12.72,PBP,-1.65133,0.177985,0.00620493,0.991916 beta-lactamase_625_E62F,beta-lactamase_625_62,TEM-1,beta-lactamase_625,P62593,0.991918,NO,62,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.193,-4.376,3.183,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.213352,0.00264802,0.991918 beta-lactamase_625_A170M,beta-lactamase_625_170,TEM-1,beta-lactamase_625,P62593,0.991919,NO,170,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.237,-4.595,3.358,,0.126,,L,0.46,-0.35,3.626,,64.69,AHH,-1.63267,0.213352,0.00431903,0.991919 beta-lactamase_39_T269K,beta-lactamase_39_269,TEM-1,beta-lactamase_39,P62593,0.991922,NO,269,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.156,,,,0.646,H,A,0.53,0.4,3.889,,77.62,HPH,-1.96733,0.0495842,0.00950944,0.991922 beta-lactamase_625_L248T,beta-lactamase_625_248,TEM-1,beta-lactamase_625,P62593,0.991929,NO,248,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.213352,0.00428493,0.991929 kka2_1:2_T85A,kka2_1:2_85,Kka2,kka2_1:2,P00552,0.991929,NO,85,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.165,-2.833,0.668,,0.576,E,B,0.22,1.39,1.853,,71.59,HPA,-2.10133,0.295029,0.00634493,0.991929 Ubiquitin_A28H,Ubiquitin_28,Uba1,Ubiquitin,P0CG48,0.991935,NO,28,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.895,-4.703,2.808,4.73736,0.369,H,A,,-0.11,,,,BHB,-1.47667,0.205827,0.000842053,0.991935 Ubiquitin_A28T,Ubiquitin_28,Uba1,Ubiquitin,P0CG48,0.991935,NO,28,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.895,-2.624,0.729,4.73736,0.369,H,A,,-0.11,,,,BHB,-1.47667,0.205827,0.000842053,0.991935 Ubiquitin_D21A,Ubiquitin_21,Uba1,Ubiquitin,P0CG48,0.991935,NO,21,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.193,-2.512,1.319,4.96432,0.165,,B,0.23,-0.53,1.013,,71.82,PAP,-1.35867,0.205827,0.000465257,0.991935 Ubiquitin_D21C,Ubiquitin_21,Uba1,Ubiquitin,P0CG48,0.991935,NO,21,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.193,-5.062,3.869,4.96432,0.165,,B,0.23,-0.53,1.013,,71.82,PAP,-1.35867,0.205827,0.000465257,0.991935 Ubiquitin_D21D,Ubiquitin_21,Uba1,Ubiquitin,P0CG48,0.991935,NO,21,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.193,-1.193,,4.96432,0.165,,B,0.23,-0.53,1.013,,71.82,PAP,-1.35867,0.205827,0.000465257,0.991935 Ubiquitin_D21E,Ubiquitin_21,Uba1,Ubiquitin,P0CG48,0.991935,NO,21,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.193,-2.183,0.99,4.96432,0.165,,B,0.23,-0.53,1.013,,71.82,PAP,-1.35867,0.205827,0.000465257,0.991935 Ubiquitin_D21M,Ubiquitin_21,Uba1,Ubiquitin,P0CG48,0.991935,NO,21,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.193,-4.832,3.639,4.96432,0.165,,B,0.23,-0.53,1.013,,71.82,PAP,-1.35867,0.205827,0.000465257,0.991935 Ubiquitin_D21S,Ubiquitin_21,Uba1,Ubiquitin,P0CG48,0.991935,NO,21,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.193,-3.207,2.014,4.96432,0.165,,B,0.23,-0.53,1.013,,71.82,PAP,-1.35867,0.205827,0.000465257,0.991935 Ubiquitin_D32D,Ubiquitin_32,Uba1,Ubiquitin,P0CG48,0.991935,NO,32,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.451,-1.451,0,4.96502,0.835,H,A,,1.4,,,,PAB,-1.47067,0.205827,0.000758819,0.991935 Ubiquitin_D39A,Ubiquitin_39,Uba1,Ubiquitin,P0CG48,0.991935,NO,39,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.792,-2.662,0.87,5.1607,0.433,G,A,,0.55,,,,OAP,-1.754,0.205827,0.00071409,0.991935 Ubiquitin_D39P,Ubiquitin_39,Uba1,Ubiquitin,P0CG48,0.991935,NO,39,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.792,-2.938,1.146,5.1607,0.433,G,A,,0.55,,,,OAP,-1.754,0.205827,0.00071409,0.991935 Ubiquitin_D39Q,Ubiquitin_39,Uba1,Ubiquitin,P0CG48,0.991935,NO,39,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.792,-3.874,2.082,5.1607,0.433,G,A,,0.55,,,,OAP,-1.754,0.205827,0.00071409,0.991935 Ubiquitin_D39S,Ubiquitin_39,Uba1,Ubiquitin,P0CG48,0.991935,NO,39,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.792,-2.537,0.745,5.1607,0.433,G,A,,0.55,,,,OAP,-1.754,0.205827,0.00071409,0.991935 Ubiquitin_D58A,Ubiquitin_58,Uba1,Ubiquitin,P0CG48,0.991935,NO,58,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.622,-2.671,1.049,5.06391,0.457,G,A,,-0.54,,,,PAH,-1.60267,0.205827,0.000639847,0.991935 Ubiquitin_E16A,Ubiquitin_16,Uba1,Ubiquitin,P0CG48,0.991935,NO,16,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.545,-3.208,1.663,5.07465,0.567,E,B,,0.59,,,,HAH,-1.31367,0.205827,0.000786769,0.991935 Ubiquitin_E16D,Ubiquitin_16,Uba1,Ubiquitin,P0CG48,0.991935,NO,16,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.545,-1.894,0.349,5.07465,0.567,E,B,,0.59,,,,HAH,-1.31367,0.205827,0.000786769,0.991935 Ubiquitin_E16G,Ubiquitin_16,Uba1,Ubiquitin,P0CG48,0.991935,NO,16,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.545,-2.468,0.923,5.07465,0.567,E,B,,0.59,,,,HAH,-1.31367,0.205827,0.000786769,0.991935 Ubiquitin_E16H,Ubiquitin_16,Uba1,Ubiquitin,P0CG48,0.991935,NO,16,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.545,-4.392,2.847,5.07465,0.567,E,B,,0.59,,,,HAH,-1.31367,0.205827,0.000786769,0.991935 Ubiquitin_E16L,Ubiquitin_16,Uba1,Ubiquitin,P0CG48,0.991935,NO,16,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.545,-3.68,2.135,5.07465,0.567,E,B,,0.59,,,,HAH,-1.31367,0.205827,0.000786769,0.991935 Ubiquitin_E16M,Ubiquitin_16,Uba1,Ubiquitin,P0CG48,0.991935,NO,16,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.545,-4.802,3.257,5.07465,0.567,E,B,,0.59,,,,HAH,-1.31367,0.205827,0.000786769,0.991935 Ubiquitin_E16N,Ubiquitin_16,Uba1,Ubiquitin,P0CG48,0.991935,NO,16,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.545,-2.375,0.83,5.07465,0.567,E,B,,0.59,,,,HAH,-1.31367,0.205827,0.000786769,0.991935 Ubiquitin_E16T,Ubiquitin_16,Uba1,Ubiquitin,P0CG48,0.991935,NO,16,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.545,-3.485,1.94,5.07465,0.567,E,B,,0.59,,,,HAH,-1.31367,0.205827,0.000786769,0.991935 Ubiquitin_E34A,Ubiquitin_34,Uba1,Ubiquitin,P0CG48,0.991935,NO,34,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.294,-3.132,1.838,5.02178,0.406,H,A,1.62,0.6,1.295,,35.62,BAO,-1.24933,0.205827,0.000686048,0.991935 Ubiquitin_E34D,Ubiquitin_34,Uba1,Ubiquitin,P0CG48,0.991935,NO,34,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.294,-2.453,1.159,5.02178,0.406,H,A,1.62,0.6,1.295,,35.62,BAO,-1.24933,0.205827,0.000686048,0.991935 Ubiquitin_E34S,Ubiquitin_34,Uba1,Ubiquitin,P0CG48,0.991935,NO,34,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.294,-3.274,1.98,5.02178,0.406,H,A,1.62,0.6,1.295,,35.62,BAO,-1.24933,0.205827,0.000686048,0.991935 Ubiquitin_E64G,Ubiquitin_64,Uba1,Ubiquitin,P0CG48,0.991935,NO,64,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.763,-2.356,0.593,5.084,0.54,T,l,,0.79,,,,BAP,-1.64433,0.205827,0.000817406,0.991935 Ubiquitin_E64L,Ubiquitin_64,Uba1,Ubiquitin,P0CG48,0.991935,NO,64,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.763,-3.616,1.853,5.084,0.54,T,l,,0.79,,,,BAP,-1.64433,0.205827,0.000817406,0.991935 Ubiquitin_E64T,Ubiquitin_64,Uba1,Ubiquitin,P0CG48,0.991935,NO,64,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.763,-2.895,1.132,5.084,0.54,T,l,,0.79,,,,BAP,-1.64433,0.205827,0.000817406,0.991935 Ubiquitin_F45C,Ubiquitin_45,Uba1,Ubiquitin,P0CG48,0.991935,NO,45,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.322,-4.855,3.533,4.80693,0.26,E,B,1.62,-0.99,1.531,,53.87,HHH,-1.55267,0.205827,0.000470401,0.991935 Ubiquitin_F45S,Ubiquitin_45,Uba1,Ubiquitin,P0CG48,0.991935,NO,45,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.322,-3.596,2.274,4.80693,0.26,E,B,1.62,-0.99,1.531,,53.87,HHH,-1.55267,0.205827,0.000470401,0.991935 Ubiquitin_F45Y,Ubiquitin_45,Uba1,Ubiquitin,P0CG48,0.991935,NO,45,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.322,-2.336,1.014,4.80693,0.26,E,B,1.62,-0.99,1.531,,53.87,HHH,-1.55267,0.205827,0.000470401,0.991935 Ubiquitin_F4F,Ubiquitin_4,Uba1,Ubiquitin,P0CG48,0.991935,NO,4,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.534,-1.534,,4.77459,0.059,E,B,,-0.46,,,,HHH,-1.504,0.205827,0.000805043,0.991935 Ubiquitin_I13T,Ubiquitin_13,Uba1,Ubiquitin,P0CG48,0.991935,NO,13,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.554,-3.538,1.984,5.19411,0.038,E,B,,-0.2,,,,PHP,-1.48,0.205827,0.000716423,0.991935 Ubiquitin_I36M,Ubiquitin_36,Uba1,Ubiquitin,P0CG48,0.991935,NO,36,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.477,-4.215,2.738,5.1035,0.203,,B,0.27,-0.22,1.552,,30.8,OHO,-1.30767,0.205827,0.000630555,0.991935 Ubiquitin_I44I,Ubiquitin_44,Uba1,Ubiquitin,P0CG48,0.991935,NO,44,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.566,-1.566,0,4.71256,,E,B,0.27,-1.17,5.26,,39.71,HHH,-1.38567,0.205827,0.000613305,0.991935 Ubiquitin_K11K,Ubiquitin_11,Uba1,Ubiquitin,P0CG48,0.991935,NO,11,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.354,-1.354,,5.16813,0.401,,B,2.81,0.84,0.335,,25.84,OBP,-1.346,0.205827,0.000535553,0.991935 Ubiquitin_K29H,Ubiquitin_29,Uba1,Ubiquitin,P0CG48,0.991935,NO,29,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.471,-3.124,1.653,4.74832,0.355,H,A,,-0.06,,,,HBH,-1.52367,0.205827,0.000900239,0.991935 Ubiquitin_K29S,Ubiquitin_29,Uba1,Ubiquitin,P0CG48,0.991935,NO,29,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.471,-3.348,1.877,4.74832,0.355,H,A,,-0.06,,,,HBH,-1.52367,0.205827,0.000900239,0.991935 Ubiquitin_K33K,Ubiquitin_33,Uba1,Ubiquitin,P0CG48,0.991935,NO,33,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.283,-1.283,0,5.08526,0.64,H,A,1.82,1.2,1.509,,51.09,ABA,-1.34267,0.205827,0.000712743,0.991935 Ubiquitin_K6K,Ubiquitin_6,Uba1,Ubiquitin,P0CG48,0.991935,NO,6,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.093,-1.093,,4.84211,0.35,E,B,1.82,-0.62,1.502,,71.82,HBP,-1.36133,0.205827,0.000784795,0.991935 Ubiquitin_L15F,Ubiquitin_15,Uba1,Ubiquitin,P0CG48,0.991935,NO,15,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.082,-3.678,2.596,5.14718,0.029,E,B,1.16,-0.53,0.936,,38.69,PHA,-1.40833,0.205827,0.000519738,0.991935 Ubiquitin_L15T,Ubiquitin_15,Uba1,Ubiquitin,P0CG48,0.991935,NO,15,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.082,-3.405,2.323,5.14718,0.029,E,B,1.16,-0.53,0.936,,38.69,PHA,-1.40833,0.205827,0.000519738,0.991935 Ubiquitin_L43L,Ubiquitin_43,Uba1,Ubiquitin,P0CG48,0.991935,NO,43,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.269,-1.269,0,4.8799,,E,B,1.75,-1.17,10.246,10.246,53.87,BHH,-1.46867,0.205827,0.000572481,0.991935 Ubiquitin_L50M,Ubiquitin_50,Uba1,Ubiquitin,P0CG48,0.991935,NO,50,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.107,-2.8,1.693,5.19399,0.029,,B,,-0.92,,,,PHA,-1.52733,0.205827,0.000734242,0.991935 Ubiquitin_L56I,Ubiquitin_56,Uba1,Ubiquitin,P0CG48,0.991935,NO,56,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.324,-2.354,1.03,4.83362,,T,A,,-0.91,,,,PHP,-1.60067,0.205827,0.000459465,0.991935 Ubiquitin_L73L,Ubiquitin_73,Uba1,Ubiquitin,P0CG48,0.991935,NO,73,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.801,-1.801,0,5.27116,0.518,,B,0.77,1,10.519,10.519,34.31,BHB,-1.858,0.205827,0.000710624,0.991935 Ubiquitin_N25E,Ubiquitin_25,Uba1,Ubiquitin,P0CG48,0.991935,NO,25,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-1.95,-3.356,1.406,4.76563,0.444,H,A,0.09,0,2.3,,31.09,APH,-1.741,0.205827,0.00071919,0.991935 Ubiquitin_P19C,Ubiquitin_19,Uba1,Ubiquitin,P0CG48,0.991935,NO,19,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-2.352,-3.349,0.997,4.67617,0.398,T,A,,-0.61,,,,AOP,-1.86233,0.205827,0.000729653,0.991935 Ubiquitin_P19D,Ubiquitin_19,Uba1,Ubiquitin,P0CG48,0.991935,NO,19,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-2.352,-3.661,1.309,4.67617,0.398,T,A,,-0.61,,,,AOP,-1.86233,0.205827,0.000729653,0.991935 Ubiquitin_P19E,Ubiquitin_19,Uba1,Ubiquitin,P0CG48,0.991935,NO,19,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-2.352,-2.888,0.536,4.67617,0.398,T,A,,-0.61,,,,AOP,-1.86233,0.205827,0.000729653,0.991935 Ubiquitin_P19G,Ubiquitin_19,Uba1,Ubiquitin,P0CG48,0.991935,NO,19,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-2.352,-2.502,0.15,4.67617,0.398,T,A,,-0.61,,,,AOP,-1.86233,0.205827,0.000729653,0.991935 Ubiquitin_P19L,Ubiquitin_19,Uba1,Ubiquitin,P0CG48,0.991935,NO,19,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-2.352,-3.491,1.139,4.67617,0.398,T,A,,-0.61,,,,AOP,-1.86233,0.205827,0.000729653,0.991935 Ubiquitin_P19P,Ubiquitin_19,Uba1,Ubiquitin,P0CG48,0.991935,NO,19,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-2.352,-2.352,,4.67617,0.398,T,A,,-0.61,,,,AOP,-1.86233,0.205827,0.000729653,0.991935 Ubiquitin_P19Q,Ubiquitin_19,Uba1,Ubiquitin,P0CG48,0.991935,NO,19,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-2.352,-3.103,0.751,4.67617,0.398,T,A,,-0.61,,,,AOP,-1.86233,0.205827,0.000729653,0.991935 Ubiquitin_P19V,Ubiquitin_19,Uba1,Ubiquitin,P0CG48,0.991935,NO,19,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-2.352,-2.911,0.559,4.67617,0.398,T,A,,-0.61,,,,AOP,-1.86233,0.205827,0.000729653,0.991935 Ubiquitin_P37C,Ubiquitin_37,Uba1,Ubiquitin,P0CG48,0.991935,NO,37,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.275,-4.922,3.647,5.06918,0.323,,B,,-0.09,,,,HOO,-1.49,0.205827,0.000600764,0.991935 Ubiquitin_P37H,Ubiquitin_37,Uba1,Ubiquitin,P0CG48,0.991935,NO,37,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.275,-3.023,1.748,5.06918,0.323,,B,,-0.09,,,,HOO,-1.49,0.205827,0.000600764,0.991935 Ubiquitin_P37L,Ubiquitin_37,Uba1,Ubiquitin,P0CG48,0.991935,NO,37,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.275,-2.635,1.36,5.06918,0.323,,B,,-0.09,,,,HOO,-1.49,0.205827,0.000600764,0.991935 Ubiquitin_Q31M,Ubiquitin_31,Uba1,Ubiquitin,P0CG48,0.991935,NO,31,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-1.678,-4.623,2.945,4.5004,0.464,H,A,,0.68,,,,HPA,-1.44467,0.205827,0.000724141,0.991935 Ubiquitin_Q31Q,Ubiquitin_31,Uba1,Ubiquitin,P0CG48,0.991935,NO,31,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-1.678,-1.678,0,4.5004,0.464,H,A,,0.68,,,,HPA,-1.44467,0.205827,0.000724141,0.991935 Ubiquitin_Q31R,Ubiquitin_31,Uba1,Ubiquitin,P0CG48,0.991935,NO,31,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-1.678,-2.547,0.869,4.5004,0.464,H,A,,0.68,,,,HPA,-1.44467,0.205827,0.000724141,0.991935 Ubiquitin_Q31V,Ubiquitin_31,Uba1,Ubiquitin,P0CG48,0.991935,NO,31,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-1.678,-3.723,2.045,4.5004,0.464,H,A,,0.68,,,,HPA,-1.44467,0.205827,0.000724141,0.991935 Ubiquitin_Q41S,Ubiquitin_41,Uba1,Ubiquitin,P0CG48,0.991935,NO,41,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-1.329,-3.3,1.971,4.9201,0.017,E,B,0.12,-0.98,0.812,,30.07,PPB,-1.55067,0.205827,0.000521668,0.991935 Ubiquitin_Q62C,Ubiquitin_62,Uba1,Ubiquitin,P0CG48,0.991935,NO,62,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-1.836,-3.356,1.52,5.33616,0.762,,B,,0.79,,,,HPB,-1.66167,0.205827,0.00068944,0.991935 Ubiquitin_Q62D,Ubiquitin_62,Uba1,Ubiquitin,P0CG48,0.991935,NO,62,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-1.836,-3.505,1.669,5.33616,0.762,,B,,0.79,,,,HPB,-1.66167,0.205827,0.00068944,0.991935 Ubiquitin_Q62R,Ubiquitin_62,Uba1,Ubiquitin,P0CG48,0.991935,NO,62,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-1.836,-2.695,0.859,5.33616,0.762,,B,,0.79,,,,HPB,-1.66167,0.205827,0.00068944,0.991935 Ubiquitin_R54G,Ubiquitin_54,Uba1,Ubiquitin,P0CG48,0.991935,NO,54,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.037,-2.775,0.738,5.14935,0.41,S,B,,0.87,,,,OBP,-1.72667,0.205827,0.000581095,0.991935 Ubiquitin_R54L,Ubiquitin_54,Uba1,Ubiquitin,P0CG48,0.991935,NO,54,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.037,-2.598,0.561,5.14935,0.41,S,B,,0.87,,,,OBP,-1.72667,0.205827,0.000581095,0.991935 Ubiquitin_R54M,Ubiquitin_54,Uba1,Ubiquitin,P0CG48,0.991935,NO,54,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.037,-4.64,2.603,5.14935,0.41,S,B,,0.87,,,,OBP,-1.72667,0.205827,0.000581095,0.991935 Ubiquitin_R54T,Ubiquitin_54,Uba1,Ubiquitin,P0CG48,0.991935,NO,54,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.037,-2.865,0.828,5.14935,0.41,S,B,,0.87,,,,OBP,-1.72667,0.205827,0.000581095,0.991935 Ubiquitin_R54Y,Ubiquitin_54,Uba1,Ubiquitin,P0CG48,0.991935,NO,54,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.037,-3.114,1.077,5.14935,0.41,S,B,,0.87,,,,OBP,-1.72667,0.205827,0.000581095,0.991935 Ubiquitin_S20A,Ubiquitin_20,Uba1,Ubiquitin,P0CG48,0.991935,NO,20,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.539,-2.425,0.886,5.15339,0.672,T,A,,-0.6,,,,OPA,-1.69467,0.205827,0.000670478,0.991935 Ubiquitin_S20D,Ubiquitin_20,Uba1,Ubiquitin,P0CG48,0.991935,NO,20,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.539,-3.395,1.856,5.15339,0.672,T,A,,-0.6,,,,OPA,-1.69467,0.205827,0.000670478,0.991935 Ubiquitin_S20E,Ubiquitin_20,Uba1,Ubiquitin,P0CG48,0.991935,NO,20,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.539,-2.668,1.129,5.15339,0.672,T,A,,-0.6,,,,OPA,-1.69467,0.205827,0.000670478,0.991935 Ubiquitin_S20F,Ubiquitin_20,Uba1,Ubiquitin,P0CG48,0.991935,NO,20,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.539,-4.283,2.744,5.15339,0.672,T,A,,-0.6,,,,OPA,-1.69467,0.205827,0.000670478,0.991935 Ubiquitin_S20Q,Ubiquitin_20,Uba1,Ubiquitin,P0CG48,0.991935,NO,20,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.539,-3.807,2.268,5.15339,0.672,T,A,,-0.6,,,,OPA,-1.69467,0.205827,0.000670478,0.991935 Ubiquitin_S57C,Ubiquitin_57,Uba1,Ubiquitin,P0CG48,0.991935,NO,57,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.879,-3.303,1.424,4.65125,0.456,G,A,,-0.42,,,,HPA,-1.60833,0.205827,0.000948086,0.991935 Ubiquitin_S57F,Ubiquitin_57,Uba1,Ubiquitin,P0CG48,0.991935,NO,57,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.879,-4.235,2.356,4.65125,0.456,G,A,,-0.42,,,,HPA,-1.60833,0.205827,0.000948086,0.991935 Ubiquitin_S57N,Ubiquitin_57,Uba1,Ubiquitin,P0CG48,0.991935,NO,57,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.879,-3.792,1.913,4.65125,0.456,G,A,,-0.42,,,,HPA,-1.60833,0.205827,0.000948086,0.991935 Ubiquitin_S57S,Ubiquitin_57,Uba1,Ubiquitin,P0CG48,0.991935,NO,57,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.879,-1.879,0,4.65125,0.456,G,A,,-0.42,,,,HPA,-1.60833,0.205827,0.000948086,0.991935 Ubiquitin_S65C,Ubiquitin_65,Uba1,Ubiquitin,P0CG48,0.991935,NO,65,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.535,-4.912,3.377,4.99442,0.168,,b,0.25,-0.68,16.756,16.756,33.87,APP,-1.626,0.205827,0.000546776,0.991935 Ubiquitin_S65M,Ubiquitin_65,Uba1,Ubiquitin,P0CG48,0.991935,NO,65,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.535,-4.669,3.134,4.99442,0.168,,b,0.25,-0.68,16.756,16.756,33.87,APP,-1.626,0.205827,0.000546776,0.991935 Ubiquitin_T12T,Ubiquitin_12,Uba1,Ubiquitin,P0CG48,0.991935,NO,12,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.288,-1.288,,4.93973,0.417,E,B,0.8,0.12,2.762,,25.84,BPH,-1.39867,0.205827,0.000657544,0.991935 Ubiquitin_T14A,Ubiquitin_14,Uba1,Ubiquitin,P0CG48,0.991935,NO,14,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.598,-2.321,0.723,5.10811,0.345,E,B,,-0.37,,,,HPH,-1.41133,0.205827,0.000632754,0.991935 Ubiquitin_T14C,Ubiquitin_14,Uba1,Ubiquitin,P0CG48,0.991935,NO,14,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.598,-4.876,3.278,5.10811,0.345,E,B,,-0.37,,,,HPH,-1.41133,0.205827,0.000632754,0.991935 Ubiquitin_T55E,Ubiquitin_55,Uba1,Ubiquitin,P0CG48,0.991935,NO,55,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.599,-3.582,1.983,4.58329,0.173,B,B,,-0.68,,,,BPH,-1.65333,0.205827,0.000525703,0.991935 Ubiquitin_T55I,Ubiquitin_55,Uba1,Ubiquitin,P0CG48,0.991935,NO,55,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.599,-2.732,1.133,4.58329,0.173,B,B,,-0.68,,,,BPH,-1.65333,0.205827,0.000525703,0.991935 Ubiquitin_T55P,Ubiquitin_55,Uba1,Ubiquitin,P0CG48,0.991935,NO,55,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.599,-2.708,1.109,4.58329,0.173,B,B,,-0.68,,,,BPH,-1.65333,0.205827,0.000525703,0.991935 Ubiquitin_T55Q,Ubiquitin_55,Uba1,Ubiquitin,P0CG48,0.991935,NO,55,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.599,-3.097,1.498,4.58329,0.173,B,B,,-0.68,,,,BPH,-1.65333,0.205827,0.000525703,0.991935 Ubiquitin_T55V,Ubiquitin_55,Uba1,Ubiquitin,P0CG48,0.991935,NO,55,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.599,-3.321,1.722,4.58329,0.173,B,B,,-0.68,,,,BPH,-1.65333,0.205827,0.000525703,0.991935 Ubiquitin_V17L,Ubiquitin_17,Uba1,Ubiquitin,P0CG48,0.991935,NO,17,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.314,-2.366,1.052,5.26282,0.017,,B,2.78,-0.77,3.239,,71.82,AHA,-1.51833,0.205827,0.000659638,0.991935 Ubiquitin_V17M,Ubiquitin_17,Uba1,Ubiquitin,P0CG48,0.991935,NO,17,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.314,-4.225,2.911,5.26282,0.017,,B,2.78,-0.77,3.239,,71.82,AHA,-1.51833,0.205827,0.000659638,0.991935 Ubiquitin_V17S,Ubiquitin_17,Uba1,Ubiquitin,P0CG48,0.991935,NO,17,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.314,-3.48,2.166,5.26282,0.017,,B,2.78,-0.77,3.239,,71.82,AHA,-1.51833,0.205827,0.000659638,0.991935 Ubiquitin_V17T,Ubiquitin_17,Uba1,Ubiquitin,P0CG48,0.991935,NO,17,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.314,-2.343,1.029,5.26282,0.017,,B,2.78,-0.77,3.239,,71.82,AHA,-1.51833,0.205827,0.000659638,0.991935 beta-lactamase_39_E35A,beta-lactamase_39_35,TEM-1,beta-lactamase_39,P62593,0.991942,NO,35,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-0.869,-3.127,2.258,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.0495842,0.00174441,0.991942 beta-lactamase_156_G253V,beta-lactamase_156_253,TEM-1,beta-lactamase_156,P62593,0.991944,NO,253,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.111618,0.00786358,0.991944 beta-lactamase_156_P172T,beta-lactamase_156_172,TEM-1,beta-lactamase_156,P62593,0.991946,NO,172,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.998,-3.409,2.411,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.111618,0.00312594,0.991946 beta-lactamase_39_R202L,beta-lactamase_39_202,TEM-1,beta-lactamase_39,P62593,0.991951,NO,202,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.292,-3.422,2.13,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.0495842,0.00321899,0.991951 beta-lactamase_625_E102I,beta-lactamase_625_102,TEM-1,beta-lactamase_625,P62593,0.991957,NO,102,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.118,-4.045,1.927,,0.722,S,B,1.04,1.82,1.336,,73.08,HAH,-1.581,0.213352,0.00486633,0.991957 beta-lactamase_625_A225W,beta-lactamase_625_225,TEM-1,beta-lactamase_625,P62593,0.991966,NO,225,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.845,-5.541,3.696,,1,T,B,0.46,-0.38,9.874,9.874,74.48,OHO,-1.39967,0.213352,0.00465057,0.991966 beta-lactamase_39_G142E,beta-lactamase_39_142,TEM-1,beta-lactamase_39,P62593,0.99197,NO,142,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.707,-3.628,2.921,,0.034,,p,0.29,-0.64,1.947,,64.69,OOO,-0.834,0.0495842,0.00060149,0.99197 beta-lactamase_39_L284A,beta-lactamase_39_284,TEM-1,beta-lactamase_39,P62593,0.991971,NO,284,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.0495842,0.0686156,0.991971 beta-lactamase_39_W227Y,beta-lactamase_39_227,TEM-1,beta-lactamase_39,P62593,0.991971,NO,227,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-0.982,-3.356,2.374,,0.272,,B,0.47,-0.29,1.37,,74.48,OHH,-1.595,0.0495842,0.00226019,0.991971 beta-lactamase_0_M66V,beta-lactamase_0_66,TEM-1,beta-lactamase_0,P62593,0.991972,NO,66,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.362,-2.395,1.033,,0.013,,A,0.55,-0.7,1.204,,73.08,OHH,-1.49567,0.0500837,0.00412876,0.991972 beta-lactamase_156_H94N,beta-lactamase_156_94,TEM-1,beta-lactamase_156,P62593,0.991975,NO,94,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-2.5,-3.811,1.311,,0.776,,B,0.17,1.24,11.583,11.583,77.62,HBH,-1.872,0.111618,0.00389226,0.991975 beta-lactamase_2500_V72P,beta-lactamase_2500_72,TEM-1,beta-lactamase_2500,P62593,0.991977,NO,72,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.658,-2.442,0.784,,,H,A,0.44,-1.03,2.079,,65.73,BHH,-1.32167,0.361275,0.00501194,0.991977 beta-lactamase_2500_Q204M,beta-lactamase_2500_204,TEM-1,beta-lactamase_2500,P62593,0.991979,NO,204,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-1.382,-4.445,3.063,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.361275,0.00364106,0.991979 beta-lactamase_39_T193M,beta-lactamase_39_193,TEM-1,beta-lactamase_39,P62593,0.991979,NO,193,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.914,-4.362,2.448,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.0495842,0.00482669,0.991979 beta-lactamase_39_Y95T,beta-lactamase_39_95,TEM-1,beta-lactamase_39,P62593,0.991984,NO,95,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-1.715,-3.697,1.982,,0.122,,b,0.21,-0.37,2.341,,77.62,BHP,-2.16167,0.0495842,0.00479449,0.991984 beta-lactamase_0_S51L,beta-lactamase_0_51,TEM-1,beta-lactamase_0,P62593,0.991985,NO,51,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.526,-3.495,1.969,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.0500837,0.00504821,0.991985 beta-lactamase_39_K53V,beta-lactamase_39_53,TEM-1,beta-lactamase_39,P62593,0.99199,NO,53,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-2.313,-3.678,1.365,,0.589,,B,2.34,1.15,15.633,15.633,77.62,OBH,-2.1,0.0495842,0.00383383,0.99199 beta-lactamase_2500_N173T,beta-lactamase_2500_173,TEM-1,beta-lactamase_2500,P62593,0.991991,NO,173,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-2.663,-3.589,0.926,,1.044,T,l,0.61,1.25,1.88,,77.62,OPA,-1.46633,0.361275,0.0033769,0.991991 beta-lactamase_156_S104C,beta-lactamase_156_104,TEM-1,beta-lactamase_156,P62593,0.992005,NO,104,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.015,-2.945,1.93,,0.04,,b,0.27,0.57,4.02,,63.29,HPO,-1.05267,0.111618,0.00218083,0.992005 beta-lactamase_39_L38F,beta-lactamase_39_38,TEM-1,beta-lactamase_39,P62593,0.992007,NO,38,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.343,-3.81,2.467,,0.088,H,A,0.55,0.2,17.089,17.089,64.34,PHO,-1.78033,0.0495842,0.00373244,0.992007 beta-lactamase_625_G90H,beta-lactamase_625_90,TEM-1,beta-lactamase_625,P62593,0.992008,NO,90,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-2.091,-3.353,1.262,,0.598,T,A,0.29,0.32,0.319,,77.62,HOB,-1.52633,0.213352,0.00490273,0.992008 beta-lactamase_625_P255I,beta-lactamase_625_255,TEM-1,beta-lactamase_625,P62593,0.99201,NO,255,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.213352,0.00499612,0.99201 beta-lactamase_156_P143L,beta-lactamase_156_143,TEM-1,beta-lactamase_156,P62593,0.992016,NO,143,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.967,-2.577,1.61,,0.075,H,A,0.52,-0.37,0.479,,66.78,OOB,-1.354,0.111618,0.00114551,0.992016 beta-lactamase_D269L,beta-lactamase_269,TEM-1,beta-lactamase,P62593,0.992018,NO,269,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.156,-3.579,1.423,5.47645,0.646,H,A,0.23,0.4,21.796,21.796,77.62,HAA,-1.96733,0.221079,0.00950944,0.992018 beta-lactamase_156_S57N,beta-lactamase_156_57,TEM-1,beta-lactamase_156,P62593,0.992023,NO,57,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.918,-2.953,1.035,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.111618,0.00492804,0.992023 beta-lactamase_625_A40M,beta-lactamase_625_40,TEM-1,beta-lactamase_625,P62593,0.992025,NO,40,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.402,-4.684,3.282,,0.155,S,B,0.46,0.21,1.357,,73.78,OHB,-1.40267,0.213352,0.00490026,0.992025 beta-lactamase_D33E,beta-lactamase_33,TEM-1,beta-lactamase,P62593,0.992025,NO,33,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.321,-2.159,-0.162,5.05203,0.366,H,A,0.23,0.33,2.032,,77.62,BAH,-2.12133,0.221079,0.00435556,0.992025 beta-lactamase_E26G,beta-lactamase_26,TEM-1,beta-lactamase,P62593,0.992025,NO,26,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.454,-2.639,0.185,,0.54,H,A,1.04,0.98,,,93.01,OAP,-1.96167,0.221079,0.00297948,0.992025 beta-lactamase_0_E279K,beta-lactamase_0_279,TEM-1,beta-lactamase_0,P62593,0.992028,NO,279,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.0500837,0.0192826,0.992028 beta-lactamase_625_Y262V,beta-lactamase_625_262,TEM-1,beta-lactamase_625,P62593,0.992031,NO,262,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.213352,0.00853516,0.992031 beta-lactamase_156_A225N,beta-lactamase_156_225,TEM-1,beta-lactamase_156,P62593,0.992039,NO,225,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.845,-3.051,1.206,,1,T,B,0.46,-0.38,11.722,11.722,74.48,OHO,-1.39967,0.111618,0.00465057,0.992039 beta-lactamase_156_S256Q,beta-lactamase_156_256,TEM-1,beta-lactamase_156,P62593,0.992042,NO,256,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.111618,0.00710634,0.992042 beta-lactamase_39_T264G,beta-lactamase_39_264,TEM-1,beta-lactamase_39,P62593,0.992042,NO,264,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.0495842,0.0119399,0.992042 E1_Ubiquitin_F45F,E1_Ubiquitin_45,Uba1,E1_Ubiquitin,P0CG63,0.992042,NO,45,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.149,-1.149,,,0.26,E,B,,-0.99,,,,HHH,-1.316,0.18783,0.00193245,0.992042 E1_Ubiquitin_H70P,E1_Ubiquitin_70,Uba1,E1_Ubiquitin,P0CG63,0.992042,NO,70,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-1.36,,,,0.05,E,B,0.61,-0.97,,,93.18,HBH,-1.146,0.18783,0.00206914,0.992042 E1_Ubiquitin_I44H,E1_Ubiquitin_44,Uba1,E1_Ubiquitin,P0CG63,0.992042,NO,44,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.432,-2.557,1.125,,,E,B,0.27,-1.17,4.57,,78.74,HHH,-1.25633,0.18783,0.00209731,0.992042 E1_Ubiquitin_R42A,E1_Ubiquitin_42,Uba1,E1_Ubiquitin,P0CG63,0.992042,NO,42,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.302,-2.948,1.646,,0.244,E,B,,-0.54,,,,PBH,-1.24667,0.18783,0.00224033,0.992042 beta-lactamase_2500_H24V,beta-lactamase_2500_24,TEM-1,beta-lactamase_2500,P62593,0.992047,NO,24,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-2.481,-3.524,1.043,,,,,,,0.467,,93.01,OBO,-2.0035,0.361275,0.00238894,0.992047 beta-lactamase_39_E108Y,beta-lactamase_39_108,TEM-1,beta-lactamase_39,P62593,0.992049,NO,108,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.46,-4.347,2.887,,0.572,G,A,1.04,1.87,20.151,20.151,72.73,PAB,-1.437,0.0495842,0.00413372,0.992049 beta-lactamase_625_E145A,beta-lactamase_625_145,TEM-1,beta-lactamase_625,P62593,0.99205,NO,145,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.357,-1.901,-0.456,,0.545,H,A,1.04,0.79,2.64,,77.62,BAH,-2.069,0.213352,0.00553285,0.99205 beta-lactamase_L188I,beta-lactamase_188,TEM-1,beta-lactamase,P62593,0.992056,NO,188,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.166,-2.584,1.418,5.55434,,H,A,1.07,-0.3,1.574,,60.14,PHB,-1.47033,0.221079,0.00295687,0.992056 beta-lactamase_39_R239Y,beta-lactamase_39_239,TEM-1,beta-lactamase_39,P62593,0.992058,NO,239,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.0495842,0.00213852,0.992058 beta-lactamase_156_E62H,beta-lactamase_156_62,TEM-1,beta-lactamase_156,P62593,0.992061,NO,62,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.193,-4.429,3.236,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.111618,0.00264802,0.992061 beta-lactamase_156_G142N,beta-lactamase_156_142,TEM-1,beta-lactamase_156,P62593,0.992062,NO,142,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.707,-3.445,2.738,,0.034,,p,0.29,-0.64,0.325,,64.69,OOO,-0.834,0.111618,0.00060149,0.992062 beta-lactamase_39_E119A,beta-lactamase_39_119,TEM-1,beta-lactamase_39,P62593,0.992066,NO,119,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.412,-2.242,0.83,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.0495842,0.00386966,0.992066 beta-lactamase_2500_H156T,beta-lactamase_2500_156,TEM-1,beta-lactamase_2500,P62593,0.992067,NO,156,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-3.156,-2.632,-0.524,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.361275,0.00468596,0.992067 beta-lactamase_E145S,beta-lactamase_145,TEM-1,beta-lactamase,P62593,0.992069,NO,145,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.357,-2.669,0.312,5.38104,0.545,H,A,0.52,0.79,2.124,,77.62,BAH,-2.069,0.221079,0.00553285,0.992069 beta-lactamase_625_R239Q,beta-lactamase_625_239,TEM-1,beta-lactamase_625,P62593,0.992071,NO,239,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.213352,0.00213852,0.992071 beta-lactamase_625_A183I,beta-lactamase_625_183,TEM-1,beta-lactamase_625,P62593,0.992075,NO,183,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.231,-2.835,1.604,,0.155,H,A,0.46,-0.91,23.859,23.859,77.62,HHH,-1.53367,0.213352,0.00296631,0.992075 PSD95pdz3_K393F,PSD95pdz3_393,PSD95pdz3,PSD95pdz3,P31016,0.992075,NO,393,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.416,-3.974,2.558,5.42682,,,,,22.0122,,,,HBO,-1.4265,0.0758425,0.000879298,0.992075 beta-lactamase_156_G52M,beta-lactamase_156_52,TEM-1,beta-lactamase_156,P62593,0.992079,NO,52,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.149,-4.888,3.739,,0.299,,l,0.29,-0.04,1.179,,64.69,POB,-1.66267,0.111618,0.00340138,0.992079 beta-lactamase_156_L248F,beta-lactamase_156_248,TEM-1,beta-lactamase_156,P62593,0.99208,NO,248,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.111618,0.00428493,0.99208 beta-lactamase_39_L150N,beta-lactamase_39_150,TEM-1,beta-lactamase_39,P62593,0.992081,NO,150,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.326,-4.088,2.762,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.0495842,0.00463171,0.992081 beta-lactamase_156_G114W,beta-lactamase_156_114,TEM-1,beta-lactamase_156,P62593,0.992082,NO,114,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.094,-5.288,4.194,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.111618,0.00224919,0.992082 gb1_Q228E,gb1_228,gb1,gb1,P06654,0.992085,NO,228,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,,,,,,,,,,,,,OPH,-1.282,0.177985,0.00391043,0.992085 gb1_V247T,gb1_247,gb1,gb1,P06654,0.992085,NO,247,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.711,-1.787,0.076,,,,,,,0.805,,44.87,HHA,-1.485,0.177985,0.00435373,0.992085 beta-lactamase_39_A247K,beta-lactamase_39_247,TEM-1,beta-lactamase_39,P62593,0.992087,NO,247,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.0495842,0.00611275,0.992087 beta-lactamase_39_D271I,beta-lactamase_39_271,TEM-1,beta-lactamase_39,P62593,0.992088,NO,271,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.0495842,0.00752082,0.992088 beta-lactamase_2500_E108T,beta-lactamase_2500_108,TEM-1,beta-lactamase_2500,P62593,0.992089,NO,108,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.46,-3.526,2.066,,0.572,G,A,1.04,1.87,1.147,,72.73,PAB,-1.437,0.361275,0.00413372,0.992089 beta-lactamase_2500_D207H,beta-lactamase_2500_207,TEM-1,beta-lactamase_2500,P62593,0.992093,NO,207,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.064,-3.07,1.006,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.361275,0.00592942,0.992093 beta-lactamase_I11W,beta-lactamase_11,TEM-1,beta-lactamase,P62593,0.992101,NO,11,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.745,-5.094,3.349,,,,,,,3.135,,66.08,HHO,-1.79467,0.221079,0.00261325,0.992101 beta-lactamase_625_P143S,beta-lactamase_625_143,TEM-1,beta-lactamase_625,P62593,0.992105,NO,143,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.967,-3.441,2.474,,0.075,H,A,0.52,-0.37,1.445,,66.78,OOB,-1.354,0.213352,0.00114551,0.992105 beta-lactamase_39_V101M,beta-lactamase_39_101,TEM-1,beta-lactamase_39,P62593,0.992107,NO,101,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.295,-2.812,1.517,,0.342,,B,0.44,0,2.96,,73.08,HHA,-1.54367,0.0495842,0.00374492,0.992107 kka2_1:8_E3P,kka2_1:8_3,Kka2,kka2_1:8,P00552,0.992107,NO,3,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.199,-3.691,1.492,,,,,,,7.22,,92.05,HAP,-2.11567,0.100394,0.00267607,0.992107 kka2_1:8_E3P,kka2_1:8_3,Kka2,kka2_1:8,P00552,0.992107,NO,3,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.199,-3.691,1.492,,,,,,,7.22,,92.05,HAP,-2.11567,0.100394,0.00267607,0.992107 beta-lactamase_156_L137S,beta-lactamase_156_137,TEM-1,beta-lactamase_156,P62593,0.992109,NO,137,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.03,-3.64,2.61,,,H,A,0.55,-0.38,0.674,,42.31,HHP,-1.58933,0.111618,0.00278599,0.992109 beta-lactamase_2500_L199Q,beta-lactamase_2500_199,TEM-1,beta-lactamase_2500,P62593,0.992111,NO,199,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-2.942,-3.22,0.278,,0.832,H,A,0.55,0.42,15.504,15.504,77.62,PHH,-2.32933,0.361275,0.0048649,0.992111 beta-lactamase_156_Q86K,beta-lactamase_156_86,TEM-1,beta-lactamase_156,P62593,0.992112,NO,86,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.4,-2.554,0.154,,0.696,S,A,0.64,2.38,27.704,27.704,77.62,OPA,-1.61067,0.111618,0.00450027,0.992112 beta-lactamase_156_G76T,beta-lactamase_156_76,TEM-1,beta-lactamase_156,P62593,0.992113,NO,76,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.189,-2.655,1.466,,,H,A,0.29,-0.67,3.059,,67.83,OOH,-1.22267,0.111618,0.00476637,0.992113 beta-lactamase_2500_T198E,beta-lactamase_2500_198,TEM-1,beta-lactamase_2500,P62593,0.992116,NO,198,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.168,-3.379,1.211,,0.489,,B,0.22,-0.13,0.37,,73.78,HPH,-1.98767,0.361275,0.004311,0.992116 beta-lactamase_625_M270R,beta-lactamase_625_270,TEM-1,beta-lactamase_625,P62593,0.992116,NO,270,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.213352,0.00767762,0.992116 beta-lactamase_39_L146W,beta-lactamase_39_146,TEM-1,beta-lactamase_39,P62593,0.99212,NO,146,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.462,-2.894,1.432,,0.007,H,A,0.55,-0.56,1.953,,64.69,AHP,-1.656,0.0495842,0.00474542,0.99212 beta-lactamase_39_I54G,beta-lactamase_39_54,TEM-1,beta-lactamase_39,P62593,0.992121,NO,54,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-2.838,-3.612,0.774,,0.669,E,B,0.48,-0.14,1.349,,73.78,BHH,-2.337,0.0495842,0.00403589,0.992121 beta-lactamase_39_E61N,beta-lactamase_39_61,TEM-1,beta-lactamase_39,P62593,0.992128,NO,61,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.115,-2.373,0.258,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.0495842,0.00440955,0.992128 beta-lactamase_625_E175F,beta-lactamase_625_175,TEM-1,beta-lactamase_625,P62593,0.992129,NO,175,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.336,-4.36,2.024,,0.551,,A,1.04,1.05,8.527,8.527,77.62,AAB,-1.31233,0.213352,0.00482205,0.992129 beta-lactamase_156_S201P,beta-lactamase_156_201,TEM-1,beta-lactamase_156,P62593,0.99213,NO,201,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.183,-3.79,2.607,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.111618,0.00198815,0.99213 beta-lactamase_S80Q,beta-lactamase_80,TEM-1,beta-lactamase,P62593,0.992131,NO,80,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.029,-3.941,1.912,5.23748,0.192,H,A,0.25,0.46,2.256,,77.62,HPB,-1.44567,0.221079,0.00565569,0.992131 beta-lactamase_156_P143G,beta-lactamase_156_143,TEM-1,beta-lactamase_156,P62593,0.992133,NO,143,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.967,-3.499,2.532,,0.075,H,A,0.52,-0.37,0.479,,66.78,OOB,-1.354,0.111618,0.00114551,0.992133 beta-lactamase_0_R257T,beta-lactamase_0_257,TEM-1,beta-lactamase_0,P62593,0.992135,NO,257,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.0500837,0.00756629,0.992135 beta-lactamase_39_D33F,beta-lactamase_39_33,TEM-1,beta-lactamase_39,P62593,0.992136,NO,33,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.321,-4.288,1.967,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.0495842,0.00435556,0.992136 beta-lactamase_156_Y103A,beta-lactamase_156_103,TEM-1,beta-lactamase_156,P62593,0.992137,NO,103,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-1.33,-3.426,2.096,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.111618,0.00443048,0.992137 beta-lactamase_156_S221R,beta-lactamase_156_221,TEM-1,beta-lactamase_156,P62593,0.99214,NO,221,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.754,-2.83,1.076,,0.624,H,A,0.27,-0.2,17.729,17.729,74.48,BPH,-1.59967,0.111618,0.0046094,0.99214 beta-lactamase_39_N152S,beta-lactamase_39_152,TEM-1,beta-lactamase_39,P62593,0.992143,NO,152,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-2.757,-1.988,-0.769,,0.863,H,A,0.61,0.92,4.038,,77.62,BPH,-2.97,0.0495842,0.00471429,0.992143 beta-lactamase_D250F,beta-lactamase_250,TEM-1,beta-lactamase,P62593,0.992143,NO,250,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.335,-4.442,2.107,5.72026,0.89,T,L,0.23,1.53,24.737,24.737,66.08,OAO,-1.85133,0.221079,0.00550899,0.992143 Pab1_G163A,Pab1_163,Pab1,Pab1,P04147,0.992144,NO,163,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.809,-2.67,1.861,,0.356,B,g,,0.55,,,,POB,-1.80667,0.175299,0.00030953,0.992144 beta-lactamase_625_S96R,beta-lactamase_625_96,TEM-1,beta-lactamase_625,P62593,0.992147,NO,96,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.27,-2.133,-0.137,,0.368,,b,0.27,0.39,5.244,,73.78,HPP,-2.019,0.213352,0.00551835,0.992147 beta-lactamase_156_I125V,beta-lactamase_156_125,TEM-1,beta-lactamase_156,P62593,0.99215,NO,125,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.441,-2.101,0.66,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.111618,0.00383964,0.99215 beta-lactamase_39_Q267V,beta-lactamase_39_267,TEM-1,beta-lactamase_39,P62593,0.992151,NO,267,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.0495842,0.0102128,0.992151 beta-lactamase_39_Q204Y,beta-lactamase_39_204,TEM-1,beta-lactamase_39,P62593,0.992152,NO,204,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-1.382,-4.071,2.689,,0.204,H,A,0.64,0.09,0.489,,66.08,PPH,-1.49067,0.0495842,0.00364106,0.992152 beta-lactamase_39_R189T,beta-lactamase_39_189,TEM-1,beta-lactamase_39,P62593,0.992159,NO,189,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.844,-3.622,1.778,,0.278,H,A,1.2,1.01,12.11,12.11,72.73,HBB,-1.668,0.0495842,0.0050699,0.992159 beta-lactamase_625_I171E,beta-lactamase_625_171,TEM-1,beta-lactamase_625,P62593,0.992159,NO,171,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-2.431,-3.643,1.212,,0.361,,B,0.48,0.53,3.869,,77.62,HHO,-1.55533,0.213352,0.00623355,0.992159 beta-lactamase_625_Q203K,beta-lactamase_625_203,TEM-1,beta-lactamase_625,P62593,0.992159,NO,203,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.168,-2.642,0.474,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.213352,0.00631514,0.992159 beta-lactamase_156_H24K,beta-lactamase_156_24,TEM-1,beta-lactamase_156,P62593,0.99216,NO,24,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-2.481,-3.455,0.974,,,,,,,2.708,,93.01,OBO,-2.0035,0.111618,0.00238894,0.99216 beta-lactamase_156_D207E,beta-lactamase_156_207,TEM-1,beta-lactamase_156,P62593,0.992167,NO,207,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.064,-2.615,0.551,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.111618,0.00592942,0.992167 beta-lactamase_L192F,beta-lactamase_192,TEM-1,beta-lactamase,P62593,0.99217,NO,192,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.254,-2.572,1.318,5.68899,0.095,H,A,1.3,0.35,1.756,,60.14,HHP,-1.41833,0.221079,0.00558728,0.99217 kka2_1:8_G151T,kka2_1:8_151,Kka2,kka2_1:8,P00552,0.99217,NO,151,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.873,-3.611,2.738,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.100394,0.00339918,0.99217 kka2_1:8_G151T,kka2_1:8_151,Kka2,kka2_1:8,P00552,0.99217,NO,151,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.873,-3.611,2.738,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.100394,0.00339918,0.99217 beta-lactamase_39_I258F,beta-lactamase_39_258,TEM-1,beta-lactamase_39,P62593,0.992172,NO,258,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.0495842,0.007931,0.992172 beta-lactamase_156_K53T,beta-lactamase_156_53,TEM-1,beta-lactamase_156,P62593,0.992173,NO,53,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-2.313,-2.702,0.389,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.111618,0.00383383,0.992173 beta-lactamase_39_G265R,beta-lactamase_39_265,TEM-1,beta-lactamase_39,P62593,0.992174,NO,265,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.0495842,0.00811926,0.992174 beta-lactamase_625_R81A,beta-lactamase_625_81,TEM-1,beta-lactamase_625,P62593,0.992174,NO,81,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.466,-2.609,1.143,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.213352,0.00499763,0.992174 beta-lactamase_39_H110F,beta-lactamase_39_110,TEM-1,beta-lactamase_39,P62593,0.992177,NO,110,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-1.706,-4.019,2.313,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.0495842,0.00441499,0.992177 beta-lactamase_625_V82N,beta-lactamase_625_82,TEM-1,beta-lactamase_625,P62593,0.992177,NO,82,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.325,-2.935,1.61,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.213352,0.00397046,0.992177 beta-lactamase_2500_M127V,beta-lactamase_2500_127,TEM-1,beta-lactamase_2500,P62593,0.992186,NO,127,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-2.251,-2.333,0.082,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.361275,0.00437927,0.992186 beta-lactamase_625_T126S,beta-lactamase_625_126,TEM-1,beta-lactamase_625,P62593,0.992187,NO,126,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.122,-2.464,1.342,,0.05,H,A,0.22,-0.05,0.817,,44.41,HPH,-1.60467,0.213352,0.00244552,0.992187 beta-lactamase_156_G154F,beta-lactamase_156_154,TEM-1,beta-lactamase_156,P62593,0.992192,NO,154,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.823,-4.328,3.505,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.111618,0.00180205,0.992192 beta-lactamase_625_T193W,beta-lactamase_625_193,TEM-1,beta-lactamase_625,P62593,0.992195,NO,193,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.914,-5.211,3.297,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.213352,0.00482669,0.992195 beta-lactamase_0_R159G,beta-lactamase_0_159,TEM-1,beta-lactamase_0,P62593,0.992197,NO,159,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-0.94,-3.384,2.444,,0.316,,B,1.2,-0.55,1.426,,64.34,PBH,-1.011,0.0500837,0.00108472,0.992197 beta-lactamase_156_K30C,beta-lactamase_156_30,TEM-1,beta-lactamase_156,P62593,0.992201,NO,30,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-2.307,-5.006,2.699,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.111618,0.00448593,0.992201 beta-lactamase_39_N98A,beta-lactamase_39_98,TEM-1,beta-lactamase_39,P62593,0.992201,NO,98,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-2.973,-2.132,-0.841,,0.963,G,A,0.61,1.35,14.853,14.853,77.62,PPA,-2.07867,0.0495842,0.00505389,0.992201 beta-lactamase_G52G,beta-lactamase_52,TEM-1,beta-lactamase,P62593,0.992202,NO,52,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.149,-1.149,,5.12093,0.299,,l,0.77,-0.04,2.103,,64.69,POB,-1.66267,0.221079,0.00340138,0.992202 beta-lactamase_625_E145L,beta-lactamase_625_145,TEM-1,beta-lactamase_625,P62593,0.992203,NO,145,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.357,-3.644,1.287,,0.545,H,A,1.04,0.79,2.64,,77.62,BAH,-2.069,0.213352,0.00553285,0.992203 beta-lactamase_39_T193S,beta-lactamase_39_193,TEM-1,beta-lactamase_39,P62593,0.992206,NO,193,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.914,-2.571,0.657,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.0495842,0.00482669,0.992206 beta-lactamase_156_A225L,beta-lactamase_156_225,TEM-1,beta-lactamase_156,P62593,0.992208,NO,225,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.845,-2.985,1.14,,1,T,B,0.46,-0.38,11.722,11.722,74.48,OHO,-1.39967,0.111618,0.00465057,0.992208 beta-lactamase_156_P60G,beta-lactamase_156_60,TEM-1,beta-lactamase_156,P62593,0.992208,NO,60,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-2.469,-2.095,-0.374,,0.256,T,A,0.52,-0.56,2.947,,77.62,BOA,-1.97633,0.111618,0.00521318,0.992208 beta-lactamase_156_T193N,beta-lactamase_156_193,TEM-1,beta-lactamase_156,P62593,0.992216,NO,193,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.914,-2.715,0.801,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.111618,0.00482669,0.992216 beta-lactamase_625_R239W,beta-lactamase_625_239,TEM-1,beta-lactamase_625,P62593,0.992216,NO,239,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.213352,0.00213852,0.992216 WW_domain_R187H,WW_domain_187,Yap65,WW_domain,P46937,0.992227,NO,187,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.402,-4.129,2.727,5.05189,,,,,,3.431,,78.57,PBH,-1.362,0.153962,0.00171149,0.992227 beta-lactamase_156_C121G,beta-lactamase_156_121,TEM-1,beta-lactamase_156,P62593,0.992229,NO,121,C,G,CG,Special,Special,5.07,3.29388,-1.77612,159,121,75,-46,108.5,60.1,-48.4,-0.953,-3.581,2.628,,,H,A,0.46,-0.81,1.136,,63.29,HOP,-1.46767,0.111618,0.000744322,0.992229 beta-lactamase_156_L137E,beta-lactamase_156_137,TEM-1,beta-lactamase_156,P62593,0.992229,NO,137,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.03,-3.919,2.889,,,H,A,0.55,-0.38,0.674,,42.31,HHP,-1.58933,0.111618,0.00278599,0.992229 beta-lactamase_39_S57C,beta-lactamase_39_57,TEM-1,beta-lactamase_39,P62593,0.992231,NO,57,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.918,-4.926,3.008,,0.352,E,B,0.27,-0.18,2.3,,72.73,APH,-2.29167,0.0495842,0.00492804,0.992231 beta-lactamase_0_G253R,beta-lactamase_0_253,TEM-1,beta-lactamase_0,P62593,0.992234,NO,253,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.0500837,0.00786358,0.992234 beta-lactamase_156_V157M,beta-lactamase_156_157,TEM-1,beta-lactamase_156,P62593,0.992234,NO,157,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.751,-2.587,0.836,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.111618,0.00506849,0.992234 beta-lactamase_156_D174A,beta-lactamase_156_174,TEM-1,beta-lactamase_156,P62593,0.992235,NO,174,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.738,-3.303,2.565,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.111618,0.00125633,0.992235 beta-lactamase_156_Q86M,beta-lactamase_156_86,TEM-1,beta-lactamase_156,P62593,0.992236,NO,86,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.4,-3.46,1.06,,0.696,S,A,0.64,2.38,27.704,27.704,77.62,OPA,-1.61067,0.111618,0.00450027,0.992236 beta-lactamase_0_G226T,beta-lactamase_0_226,TEM-1,beta-lactamase_0,P62593,0.992241,NO,226,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.461,-3.599,2.138,,0.701,T,l,0.29,-0.25,23.034,23.034,74.48,HOH,-1.42933,0.0500837,0.00665294,0.992241 beta-lactamase_625_T126E,beta-lactamase_625_126,TEM-1,beta-lactamase_625,P62593,0.992242,NO,126,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.122,-3.395,2.273,,0.05,H,A,0.22,-0.05,0.817,,44.41,HPH,-1.60467,0.213352,0.00244552,0.992242 beta-lactamase_625_V72S,beta-lactamase_625_72,TEM-1,beta-lactamase_625,P62593,0.992248,NO,72,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.658,-3.477,1.819,,,H,A,0.44,-1.03,0.981,,65.73,BHH,-1.32167,0.213352,0.00501194,0.992248 gb1_T279K,gb1_279,gb1,gb1,P06654,0.992254,NO,279,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.32,-3.406,2.086,,,,,,,0.529,,35.71,HPH,-1.50067,0.177985,0.00421454,0.992254 beta-lactamase_625_K109I,beta-lactamase_625_109,TEM-1,beta-lactamase_625,P62593,0.992255,NO,109,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.734,-4.102,2.368,,0.787,G,A,2.34,2.21,7.243,,72.73,ABB,-1.63333,0.213352,0.00462493,0.992255 beta-lactamase_156_K286F,beta-lactamase_156_286,TEM-1,beta-lactamase_156,P62593,0.992256,NO,286,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.111618,,0.992256 beta-lactamase_2500_D36H,beta-lactamase_2500_36,TEM-1,beta-lactamase_2500,P62593,0.992256,NO,36,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.732,-3.09,0.358,,0.555,H,A,0.75,1.17,2.26,,77.62,AAP,-1.91167,0.361275,0.00476483,0.992256 beta-lactamase_39_I140R,beta-lactamase_39_140,TEM-1,beta-lactamase_39,P62593,0.992258,NO,140,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.733,-4.193,2.46,,0.128,H,A,0.48,0.41,1.16,,73.08,PHO,-1.48733,0.0495842,0.00597777,0.992258 beta-lactamase_625_N130S,beta-lactamase_625_130,TEM-1,beta-lactamase_625,P62593,0.992264,NO,130,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-0.798,-2.936,2.138,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.213352,0.000683376,0.992264 beta-lactamase_625_R41F,beta-lactamase_625_41,TEM-1,beta-lactamase_625,P62593,0.992266,NO,41,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-0.942,-4.29,3.348,,0.321,E,B,1.2,-0.07,1.186,,65.03,HBH,-1.30267,0.213352,0.00123327,0.992266 beta-lactamase_625_A182V,beta-lactamase_625_182,TEM-1,beta-lactamase_625,P62593,0.992271,NO,182,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.777,-2.556,0.779,,0.136,H,A,0.46,-0.66,16.784,16.784,93.01,OHH,-1.27367,0.213352,0.00559099,0.992271 beta-lactamase_156_A235L,beta-lactamase_156_235,TEM-1,beta-lactamase_156,P62593,0.992272,NO,235,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.266,-3.325,2.059,,0.32,E,B,0.46,-0.86,1.344,,50,OHO,-0.89,0.111618,0.00493474,0.992272 beta-lactamase_625_D113S,beta-lactamase_625_113,TEM-1,beta-lactamase_625,P62593,0.992272,NO,113,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.829,-2.84,1.011,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.213352,0.00474112,0.992272 beta-lactamase_39_M180N,beta-lactamase_39_180,TEM-1,beta-lactamase_39,P62593,0.992279,NO,180,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-2.795,-3.603,0.808,,0.242,,B,0.55,-0.94,3.579,,77.62,PHO,-1.56433,0.0495842,0.00552048,0.992279 beta-lactamase_156_V31M,beta-lactamase_156_31,TEM-1,beta-lactamase_156,P62593,0.99229,NO,31,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.822,-3.184,1.362,,,H,A,0.44,-0.46,4.126,,73.78,BHB,-2.03767,0.111618,0.00478065,0.99229 beta-lactamase_156_P250I,beta-lactamase_156_250,TEM-1,beta-lactamase_156,P62593,0.992291,NO,250,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.111618,0.00550899,0.992291 beta-lactamase_H151V,beta-lactamase_151,TEM-1,beta-lactamase,P62593,0.992292,NO,151,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-2.96,-3.785,0.825,5.47408,0.594,H,A,0.35,0.1,1.843,,77.62,HBP,-2.34767,0.221079,0.00216946,0.992292 beta-lactamase_K30A,beta-lactamase_30,TEM-1,beta-lactamase,P62593,0.992292,NO,30,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-2.307,-2.101,-0.206,5.30605,0.142,H,A,1.82,-0.65,2.434,,93.01,HBH,-2.32833,0.221079,0.00448593,0.992292 beta-lactamase_S2Y,beta-lactamase_2,TEM-1,beta-lactamase,P62593,0.992292,NO,2,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.942,-3.986,2.044,,,,,,,2.36,,65.38,HPH,-2.02767,0.221079,0.00227352,0.992292 beta-lactamase_156_S266R,beta-lactamase_156_266,TEM-1,beta-lactamase_156,P62593,0.992299,NO,266,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.111618,0.0140785,0.992299 beta-lactamase_625_S80L,beta-lactamase_625_80,TEM-1,beta-lactamase_625,P62593,0.9923,NO,80,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.029,-2.857,0.828,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.213352,0.00565569,0.9923 kka2_1:8_G181V,kka2_1:8_181,Kka2,kka2_1:8,P00552,0.992304,NO,181,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-2.698,-2.527,-0.171,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.100394,0.00728319,0.992304 kka2_1:8_G181V,kka2_1:8_181,Kka2,kka2_1:8,P00552,0.992304,NO,181,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-2.698,-2.527,-0.171,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.100394,0.00728319,0.992304 beta-lactamase_625_A225S,beta-lactamase_625_225,TEM-1,beta-lactamase_625,P62593,0.992305,NO,225,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.845,-2.863,1.018,,1,T,B,0.46,-0.38,9.874,9.874,74.48,OHO,-1.39967,0.213352,0.00465057,0.992305 beta-lactamase_156_S51Q,beta-lactamase_156_51,TEM-1,beta-lactamase_156,P62593,0.992306,NO,51,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.526,-3.91,2.384,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.111618,0.00504821,0.992306 beta-lactamase_39_G52F,beta-lactamase_39_52,TEM-1,beta-lactamase_39,P62593,0.992306,NO,52,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.149,-4.393,3.244,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.0495842,0.00340138,0.992306 beta-lactamase_P12T,beta-lactamase_12,TEM-1,beta-lactamase,P62593,0.992313,NO,12,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-2.016,-3.377,1.361,,,,,,,2.88,,72.73,HOH,-2.05167,0.221079,0.00241653,0.992313 beta-lactamase_625_D113N,beta-lactamase_625_113,TEM-1,beta-lactamase_625,P62593,0.992321,NO,113,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.829,-3.682,1.853,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.213352,0.00474112,0.992321 beta-lactamase_39_A247C,beta-lactamase_39_247,TEM-1,beta-lactamase_39,P62593,0.992322,NO,247,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.0495842,0.00611275,0.992322 beta-lactamase_156_R91L,beta-lactamase_156_91,TEM-1,beta-lactamase_156,P62593,0.992327,NO,91,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.392,-3.471,2.079,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.111618,0.00380226,0.992327 beta-lactamase_39_I206R,beta-lactamase_39_206,TEM-1,beta-lactamase_39,P62593,0.992329,NO,206,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-2.429,-3.125,0.696,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.0495842,0.00528934,0.992329 beta-lactamase_39_G154F,beta-lactamase_39_154,TEM-1,beta-lactamase_39,P62593,0.99233,NO,154,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.823,-4.328,3.505,,0.54,T,l,0.29,-0.56,1.151,,64.69,HOA,-1.635,0.0495842,0.00180205,0.99233 beta-lactamase_156_Q276C,beta-lactamase_156_276,TEM-1,beta-lactamase_156,P62593,0.992332,NO,276,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.111618,0.0191712,0.992332 beta-lactamase_156_G90E,beta-lactamase_156_90,TEM-1,beta-lactamase_156,P62593,0.992335,NO,90,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-2.091,-2.175,0.084,,0.598,T,A,0.29,0.32,0.319,,77.62,HOB,-1.52633,0.111618,0.00490273,0.992335 beta-lactamase_156_H24E,beta-lactamase_156_24,TEM-1,beta-lactamase_156,P62593,0.992339,NO,24,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-2.481,-3.284,0.803,,,,,,,2.708,,93.01,OBO,-2.0035,0.111618,0.00238894,0.992339 beta-lactamase_625_A185V,beta-lactamase_625_185,TEM-1,beta-lactamase_625,P62593,0.992342,NO,185,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.406,-2.093,0.687,,,H,A,0.46,-1.02,0.365,,65.03,HHP,-1.84033,0.213352,0.00467449,0.992342 PSD95pdz3_A370S,PSD95pdz3_370,PSD95pdz3,PSD95pdz3,P31016,0.992342,NO,370,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.307,-2.617,1.31,5.22304,,,,,17.284,,,,PHP,-1.57967,0.0758425,0.000429106,0.992342 beta-lactamase_156_A182E,beta-lactamase_156_182,TEM-1,beta-lactamase_156,P62593,0.992344,NO,182,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.777,-2.345,0.568,,0.136,H,A,0.46,-0.66,16.784,16.784,93.01,OHH,-1.27367,0.111618,0.00559099,0.992344 beta-lactamase_625_D99S,beta-lactamase_625_99,TEM-1,beta-lactamase_625,P62593,0.992353,NO,99,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.191,-3.286,2.095,,0.402,G,A,0.75,0.36,1.318,,64.69,PAH,-1.794,0.213352,0.00305446,0.992353 beta-lactamase_156_T147L,beta-lactamase_156_147,TEM-1,beta-lactamase_156,P62593,0.992354,NO,147,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.149,-3.242,2.093,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.111618,0.00226017,0.992354 beta-lactamase_39_A123V,beta-lactamase_39_123,TEM-1,beta-lactamase_39,P62593,0.992354,NO,123,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.834,-2.392,1.558,,0.039,H,A,0.46,-0.72,0.705,,41.26,PHH,-1.47367,0.0495842,0.0010157,0.992354 beta-lactamase_156_A148G,beta-lactamase_156_148,TEM-1,beta-lactamase_156,P62593,0.992355,NO,148,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.757,-2.542,0.785,,0.379,H,A,0.46,-0.55,3.551,,72.73,PHH,-1.40167,0.111618,0.00547053,0.992355 beta-lactamase_156_N152R,beta-lactamase_156_152,TEM-1,beta-lactamase_156,P62593,0.992356,NO,152,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-2.757,-2.835,0.078,,0.863,H,A,0.61,0.92,4.038,,77.62,BPH,-2.97,0.111618,0.00471429,0.992356 beta-lactamase_39_L120A,beta-lactamase_39_120,TEM-1,beta-lactamase_39,P62593,0.992357,NO,120,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.044,-3.203,2.159,,,H,A,0.55,-1.13,22.254,22.254,64.69,AHO,-1.13633,0.0495842,0.00143563,0.992357 beta-lactamase_625_L199E,beta-lactamase_625_199,TEM-1,beta-lactamase_625,P62593,0.99236,NO,199,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-2.942,-2.604,-0.338,,0.832,H,A,0.55,0.42,1.552,,77.62,PHH,-2.32933,0.213352,0.0048649,0.99236 beta-lactamase_156_H287S,beta-lactamase_156_287,TEM-1,beta-lactamase_156,P62593,0.992362,NO,287,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,,,,,,,,,,,,,BBH,-1.111,0.111618,,0.992362 beta-lactamase_39_R242N,beta-lactamase_39_242,TEM-1,beta-lactamase_39,P62593,0.992365,NO,242,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.0495842,0.00452879,0.992365 beta-lactamase_625_E166I,beta-lactamase_625_166,TEM-1,beta-lactamase_625,P62593,0.992366,NO,166,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.756,-3.874,2.118,,0.508,G,A,1.04,1.05,2.124,,73.08,OAH,-1.42233,0.213352,0.00512989,0.992366 beta-lactamase_625_H94V,beta-lactamase_625_94,TEM-1,beta-lactamase_625,P62593,0.992367,NO,94,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-2.5,-2.751,0.251,,0.776,,B,0.17,1.24,19.42,19.42,77.62,HBH,-1.872,0.213352,0.00389226,0.992367 beta-lactamase_625_D271H,beta-lactamase_625_271,TEM-1,beta-lactamase_625,P62593,0.992373,NO,271,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.213352,0.00752082,0.992373 beta-lactamase_39_L89V,beta-lactamase_39_89,TEM-1,beta-lactamase_39,P62593,0.992374,NO,89,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.096,-3.043,1.947,,0.168,T,A,0.55,0.63,3.233,,64.34,PHO,-1.75767,0.0495842,0.00207068,0.992374 beta-lactamase_39_M67I,beta-lactamase_39_67,TEM-1,beta-lactamase_39,P62593,0.992374,NO,67,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-2.231,-2.93,0.699,,0.006,G,P,0.55,-0.81,1.463,,65.03,HHP,-1.502,0.0495842,0.00409753,0.992374 beta-lactamase_39_L196M,beta-lactamase_39_196,TEM-1,beta-lactamase_39,P62593,0.992375,NO,196,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-2.478,-3.442,0.964,,0.518,S,A,0.55,1.35,12.152,12.152,77.62,AHH,-1.839,0.0495842,0.00512144,0.992375 beta-lactamase_39_T264L,beta-lactamase_39_264,TEM-1,beta-lactamase_39,P62593,0.992377,NO,264,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.0495842,0.0119399,0.992377 beta-lactamase_625_S96P,beta-lactamase_625_96,TEM-1,beta-lactamase_625,P62593,0.99238,NO,96,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.27,-2.878,0.608,,0.368,,b,0.27,0.39,5.244,,73.78,HPP,-2.019,0.213352,0.00551835,0.99238 beta-lactamase_156_L248V,beta-lactamase_156_248,TEM-1,beta-lactamase_156,P62593,0.992382,NO,248,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.111618,0.00428493,0.992382 beta-lactamase_156_L55F,beta-lactamase_156_55,TEM-1,beta-lactamase_156,P62593,0.992384,NO,55,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.86,-2.527,0.667,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.111618,0.00403741,0.992384 beta-lactamase_625_K286W,beta-lactamase_625_286,TEM-1,beta-lactamase_625,P62593,0.992384,NO,286,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.111,-3.724,2.613,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.213352,,0.992384 beta-lactamase_156_D231A,beta-lactamase_156_231,TEM-1,beta-lactamase_156,P62593,0.992385,NO,231,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.816,-3.3,2.484,,,E,B,0.75,-1.06,2.66,,65.38,HAB,-0.994,0.111618,0.00107395,0.992385 beta-lactamase_R92L,beta-lactamase_92,TEM-1,beta-lactamase,P62593,0.992387,NO,92,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.718,-2.788,1.07,5.65832,0.479,E,B,0.91,1.36,3.069,,65.38,BBH,-1.50367,0.221079,0.00429626,0.992387 beta-lactamase_156_C75M,beta-lactamase_156_75,TEM-1,beta-lactamase_156,P62593,0.992389,NO,75,C,M,CM,Special,Hydrophobic,5.07,5.74,0.67,196,121,149,28,108.5,162.9,54.4,-1.245,-4.597,3.352,,,H,A,0.46,-0.87,0.876,,50,HOO,-1.24333,0.111618,0.0034616,0.992389 beta-lactamase_625_T198P,beta-lactamase_625_198,TEM-1,beta-lactamase_625,P62593,0.992389,NO,198,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.168,-2.894,0.726,,0.489,,B,0.22,-0.13,0.37,,73.78,HPH,-1.98767,0.213352,0.004311,0.992389 beta-lactamase_625_G253R,beta-lactamase_625_253,TEM-1,beta-lactamase_625,P62593,0.992391,NO,253,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.213352,0.00786358,0.992391 beta-lactamase_0_G243S,beta-lactamase_0_243,TEM-1,beta-lactamase_0,P62593,0.992394,NO,243,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.0500837,0.00464034,0.992394 beta-lactamase_156_L219A,beta-lactamase_156_219,TEM-1,beta-lactamase_156,P62593,0.9924,NO,219,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.313,-3.187,1.874,,,I,A,0.55,-0.51,2.321,,74.48,HHB,-1.21533,0.111618,0.00664345,0.9924 beta-lactamase_156_R91S,beta-lactamase_156_91,TEM-1,beta-lactamase_156,P62593,0.992402,NO,91,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.392,-3.342,1.95,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.111618,0.00380226,0.992402 kka2_1:8_Q136F,kka2_1:8_136,Kka2,kka2_1:8,P00552,0.992405,NO,136,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-3.021,-4.399,1.378,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.100394,0.00624149,0.992405 kka2_1:8_Q136F,kka2_1:8_136,Kka2,kka2_1:8,P00552,0.992405,NO,136,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-3.021,-4.399,1.378,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.100394,0.00624149,0.992405 beta-lactamase_39_N152P,beta-lactamase_39_152,TEM-1,beta-lactamase_39,P62593,0.992406,NO,152,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-2.757,-3.97,1.213,,0.863,H,A,0.61,0.92,4.038,,77.62,BPH,-2.97,0.0495842,0.00471429,0.992406 beta-lactamase_39_V78T,beta-lactamase_39_78,TEM-1,beta-lactamase_39,P62593,0.992407,NO,78,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.459,-3.492,2.033,,,H,A,0.44,-0.47,1.132,,63.64,HHH,-1.17833,0.0495842,0.00492501,0.992407 beta-lactamase_39_R81Q,beta-lactamase_39_81,TEM-1,beta-lactamase_39,P62593,0.992412,NO,81,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.466,-2.446,0.98,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.0495842,0.00499763,0.992412 beta-lactamase_625_R189V,beta-lactamase_625_189,TEM-1,beta-lactamase_625,P62593,0.992412,NO,189,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.844,-3.783,1.939,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.213352,0.0050699,0.992412 beta-lactamase_0_G249C,beta-lactamase_0_249,TEM-1,beta-lactamase_0,P62593,0.992413,NO,249,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.0500837,0.00220169,0.992413 beta-lactamase_156_K190I,beta-lactamase_156_190,TEM-1,beta-lactamase_156,P62593,0.992413,NO,190,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.994,-3.984,1.99,,0.371,H,A,2.34,0.16,1.513,,77.62,BBH,-1.64167,0.111618,0.00574527,0.992413 beta-lactamase_39_S57V,beta-lactamase_39_57,TEM-1,beta-lactamase_39,P62593,0.992421,NO,57,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.918,-2.889,0.971,,0.352,E,B,0.27,-0.18,2.3,,72.73,APH,-2.29167,0.0495842,0.00492804,0.992421 beta-lactamase_156_T107G,beta-lactamase_156_107,TEM-1,beta-lactamase_156,P62593,0.992423,NO,107,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.117,-3.227,2.11,,,G,A,0.22,-0.06,0.341,,67.83,HPA,-1.265,0.111618,0.00239347,0.992423 beta-lactamase_156_I171C,beta-lactamase_156_171,TEM-1,beta-lactamase_156,P62593,0.992424,NO,171,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-2.431,-4.938,2.507,,0.361,,B,0.48,0.53,3.869,,77.62,HHO,-1.55533,0.111618,0.00623355,0.992424 beta-lactamase_39_G226K,beta-lactamase_39_226,TEM-1,beta-lactamase_39,P62593,0.992432,NO,226,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.461,-2.859,1.398,,0.701,T,l,0.29,-0.25,23.034,23.034,74.48,HOH,-1.42933,0.0495842,0.00665294,0.992432 beta-lactamase_625_E102Q,beta-lactamase_625_102,TEM-1,beta-lactamase_625,P62593,0.992432,NO,102,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.118,-3.043,0.925,,0.722,S,B,1.04,1.82,1.336,,73.08,HAH,-1.581,0.213352,0.00486633,0.992432 beta-lactamase_156_R59W,beta-lactamase_156_59,TEM-1,beta-lactamase_156,P62593,0.992433,NO,59,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.345,-5.421,4.076,,0.329,S,L,1.2,-0.09,2.995,,73.08,HBO,-2.24267,0.111618,0.00318082,0.992433 beta-lactamase_625_Q267P,beta-lactamase_625_267,TEM-1,beta-lactamase_625,P62593,0.992434,NO,267,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.213352,0.0102128,0.992434 beta-lactamase_39_A34V,beta-lactamase_39_34,TEM-1,beta-lactamase_39,P62593,0.992441,NO,34,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.059,-2.227,0.168,,,H,A,0.46,-0.54,13.292,13.292,73.78,AHA,-1.74967,0.0495842,0.00407913,0.992441 beta-lactamase_L196G,beta-lactamase_196,TEM-1,beta-lactamase,P62593,0.992444,NO,196,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-2.478,-2.91,0.432,,0.518,S,A,0.55,1.35,,,77.62,AHH,-1.839,0.221079,0.00512144,0.992444 beta-lactamase_625_S283R,beta-lactamase_625_283,TEM-1,beta-lactamase_625,P62593,0.992452,NO,283,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.213352,0.0429138,0.992452 beta-lactamase_2500_Q97R,beta-lactamase_2500_97,TEM-1,beta-lactamase_2500,P62593,0.992456,NO,97,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.072,-2.428,0.356,,0.823,G,A,0.64,2.42,1.157,,77.62,PPP,-2.43833,0.361275,0.0045116,0.992456 beta-lactamase_156_P217I,beta-lactamase_156_217,TEM-1,beta-lactamase_156,P62593,0.992457,NO,217,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-2.062,-4.071,2.009,,0.496,I,A,0.52,-0.33,2.303,,74.48,OOH,-1.64333,0.111618,0.00463211,0.992457 beta-lactamase_39_L218P,beta-lactamase_39_218,TEM-1,beta-lactamase_39,P62593,0.992458,NO,218,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.391,-4.052,2.661,,,I,b,0.55,-0.53,2.038,,74.48,OHH,-1.58867,0.0495842,0.00618274,0.992458 beta-lactamase_2500_A182N,beta-lactamase_2500_182,TEM-1,beta-lactamase_2500,P62593,0.992461,NO,182,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.777,-3.015,1.238,,0.136,H,A,0.46,-0.66,2.032,,93.01,OHH,-1.27367,0.361275,0.00559099,0.992461 beta-lactamase_156_D36P,beta-lactamase_156_36,TEM-1,beta-lactamase_156,P62593,0.992474,NO,36,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.732,-3.967,1.235,,0.555,H,A,0.75,1.17,14.871,14.871,77.62,AAP,-1.91167,0.111618,0.00476483,0.992474 beta-lactamase_2500_K53M,beta-lactamase_2500_53,TEM-1,beta-lactamase_2500,P62593,0.992482,NO,53,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-2.313,-4.641,2.328,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.361275,0.00383383,0.992482 beta-lactamase_625_V82S,beta-lactamase_625_82,TEM-1,beta-lactamase_625,P62593,0.992482,NO,82,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.325,-3.501,2.176,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.213352,0.00397046,0.992482 beta-lactamase_39_L38M,beta-lactamase_39_38,TEM-1,beta-lactamase_39,P62593,0.992483,NO,38,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.343,-4.186,2.843,,0.088,H,A,0.55,0.2,17.089,17.089,64.34,PHO,-1.78033,0.0495842,0.00373244,0.992483 Pab1_E195G,Pab1_195,Pab1,Pab1,P04147,0.992484,NO,195,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.2,-3.229,2.029,,,,,,,,,,PAH,-1.72467,0.175299,0.000620107,0.992484 kka2_1:8_R202T,kka2_1:8_202,Kka2,kka2_1:8,P00552,0.992485,NO,202,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.761,-3.676,1.915,,0.607,E,B,1.2,0.48,1.409,,52.27,OBH,-1.41067,0.100394,0.00696498,0.992485 kka2_1:8_R202T,kka2_1:8_202,Kka2,kka2_1:8,P00552,0.992485,NO,202,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.761,-3.676,1.915,,0.607,E,B,1.2,0.48,1.409,,52.27,OBH,-1.41067,0.100394,0.00696498,0.992485 beta-lactamase_F13T,beta-lactamase_13,TEM-1,beta-lactamase,P62593,0.992487,NO,13,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-2.394,-2.516,0.122,,,,,,,4.079,,77.62,OHH,-2.382,0.221079,0.0029078,0.992487 beta-lactamase_2500_G85Q,beta-lactamase_2500_85,TEM-1,beta-lactamase_2500,P62593,0.992488,NO,85,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.011,-3.928,2.917,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.361275,0.00252173,0.992488 beta-lactamase_625_I171T,beta-lactamase_625_171,TEM-1,beta-lactamase_625,P62593,0.99249,NO,171,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-2.431,-2.05,-0.381,,0.361,,B,0.48,0.53,3.869,,77.62,HHO,-1.55533,0.213352,0.00623355,0.99249 beta-lactamase_156_L73Y,beta-lactamase_156_73,TEM-1,beta-lactamase_156,P62593,0.992493,NO,73,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.507,-3.917,2.41,,,H,A,0.55,-0.64,2.09,,67.83,HHH,-1.487,0.111618,0.00488983,0.992493 beta-lactamase_2500_S96L,beta-lactamase_2500_96,TEM-1,beta-lactamase_2500,P62593,0.992493,NO,96,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.27,-3.527,1.257,,0.368,,b,0.27,0.39,32.348,32.348,73.78,HPP,-2.019,0.361275,0.00551835,0.992493 beta-lactamase_625_E175T,beta-lactamase_625_175,TEM-1,beta-lactamase_625,P62593,0.992497,NO,175,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.336,-3.551,1.215,,0.551,,A,1.04,1.05,8.527,8.527,77.62,AAB,-1.31233,0.213352,0.00482205,0.992497 beta-lactamase_625_D155N,beta-lactamase_625_155,TEM-1,beta-lactamase_625,P62593,0.992502,NO,155,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.889,-2.502,1.613,,0.049,,B,0.75,-0.9,4.922,,64.69,OAB,-1.62267,0.213352,0.00135315,0.992502 beta-lactamase_39_A84P,beta-lactamase_39_84,TEM-1,beta-lactamase_39,P62593,0.992503,NO,84,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.651,-3.933,2.282,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.0495842,0.00503822,0.992503 beta-lactamase_156_T269N,beta-lactamase_156_269,TEM-1,beta-lactamase_156,P62593,0.992504,NO,269,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.111618,0.00950944,0.992504 kka2_1:2_T72E,kka2_1:2_72,Kka2,kka2_1:2,P00552,0.992509,NO,72,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.38,-2.356,-0.024,,0.784,H,A,0.82,0.29,6.463,,65.53,HPP,-2.238,0.295029,0.00750756,0.992509 beta-lactamase_156_H151L,beta-lactamase_156_151,TEM-1,beta-lactamase_156,P62593,0.992517,NO,151,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-2.96,-3.494,0.534,,0.594,H,A,0.17,0.1,1.401,,77.62,HBP,-2.34767,0.111618,0.00216946,0.992517 beta-lactamase_2500_A222E,beta-lactamase_2500_222,TEM-1,beta-lactamase_2500,P62593,0.992517,NO,222,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.103,-3.646,1.543,,0.233,H,A,0.46,-0.25,0.379,,77.62,PHH,-1.63733,0.361275,0.00466094,0.992517 beta-lactamase_0_N274R,beta-lactamase_0_274,TEM-1,beta-lactamase_0,P62593,0.992518,NO,274,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.0500837,0.0110418,0.992518 beta-lactamase_39_A215C,beta-lactamase_39_215,TEM-1,beta-lactamase_39,P62593,0.992518,NO,215,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.503,-4.816,3.313,,,,a,0.46,-0.93,0.494,,74.48,HHO,-1.42633,0.0495842,0.00544007,0.992518 beta-lactamase_625_G39C,beta-lactamase_625_39,TEM-1,beta-lactamase_625,P62593,0.992523,NO,39,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.864,-5.191,3.327,,0.701,T,L,0.29,0.47,29.926,29.926,77.62,HOH,-1.53633,0.213352,0.00487611,0.992523 beta-lactamase_156_G141P,beta-lactamase_156_141,TEM-1,beta-lactamase_156,P62593,0.992527,NO,141,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.828,-3.881,3.053,,0.575,T,l,0.29,-0.28,0.198,,64.69,HOO,-1.08933,0.111618,0.0012419,0.992527 beta-lactamase_156_Q88V,beta-lactamase_156_88,TEM-1,beta-lactamase_156,P62593,0.992527,NO,88,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.086,-3.621,1.535,,0.807,,B,0.64,2.03,0.911,,77.62,APH,-1.53433,0.111618,0.00504167,0.992527 beta-lactamase_156_G216R,beta-lactamase_156_216,TEM-1,beta-lactamase_156,P62593,0.992528,NO,216,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.477,-2.93,1.453,,0.437,I,A,0.29,-0.58,12.464,12.464,74.48,HOO,-1.68067,0.111618,0.00639568,0.992528 beta-lactamase_625_E175L,beta-lactamase_625_175,TEM-1,beta-lactamase_625,P62593,0.992528,NO,175,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.336,-3.444,1.108,,0.551,,A,1.04,1.05,8.527,8.527,77.62,AAB,-1.31233,0.213352,0.00482205,0.992528 beta-lactamase_39_R41P,beta-lactamase_39_41,TEM-1,beta-lactamase_39,P62593,0.992532,NO,41,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-0.942,-3.877,2.935,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.0495842,0.00123327,0.992532 beta-lactamase_625_R189A,beta-lactamase_625_189,TEM-1,beta-lactamase_625,P62593,0.992539,NO,189,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.844,-2.739,0.895,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.213352,0.0050699,0.992539 beta-lactamase_156_L47S,beta-lactamase_156_47,TEM-1,beta-lactamase_156,P62593,0.99254,NO,47,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.876,-3.642,1.766,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.111618,0.00439844,0.99254 beta-lactamase_625_G194F,beta-lactamase_625_194,TEM-1,beta-lactamase_625,P62593,0.99254,NO,194,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.396,-4.382,2.986,,0.276,S,b,0.29,0.36,3.593,,67.83,POA,-1.832,0.213352,0.00392163,0.99254 beta-lactamase_156_R275M,beta-lactamase_156_275,TEM-1,beta-lactamase_156,P62593,0.992542,NO,275,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.111618,0.0141984,0.992542 beta-lactamase_2500_N50L,beta-lactamase_2500_50,TEM-1,beta-lactamase_2500,P62593,0.992546,NO,50,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-2.979,-2.892,-0.087,,0.912,T,A,0.61,1.24,1.581,,77.62,HPP,-2.134,0.361275,0.0047211,0.992546 beta-lactamase_156_Q37F,beta-lactamase_156_37,TEM-1,beta-lactamase_156,P62593,0.992551,NO,37,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.134,-4.314,2.18,,0.613,H,A,0.64,1.98,12.052,12.052,73.08,APH,-2.06967,0.111618,0.00425833,0.992551 beta-lactamase_39_N134W,beta-lactamase_39_134,TEM-1,beta-lactamase_39,P62593,0.992556,NO,134,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-0.879,-5.545,4.666,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.0495842,0.000644786,0.992556 beta-lactamase_625_E166V,beta-lactamase_625_166,TEM-1,beta-lactamase_625,P62593,0.99256,NO,166,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.756,-2.896,1.14,,0.508,G,A,1.04,1.05,2.124,,73.08,OAH,-1.42233,0.213352,0.00512989,0.99256 beta-lactamase_625_P250H,beta-lactamase_625_250,TEM-1,beta-lactamase_625,P62593,0.992565,NO,250,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.213352,0.00550899,0.992565 beta-lactamase_T131S,beta-lactamase_131,TEM-1,beta-lactamase,P62593,0.992566,NO,131,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.328,-1.912,0.584,5.0548,,H,A,0.53,-0.69,3.306,,67.48,PPH,-1.00867,0.221079,0.00345886,0.992566 beta-lactamase_625_K254M,beta-lactamase_625_254,TEM-1,beta-lactamase_625,P62593,0.992568,NO,254,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.213352,0.00369,0.992568 beta-lactamase_39_Y103W,beta-lactamase_39_103,TEM-1,beta-lactamase_39,P62593,0.992573,NO,103,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-1.33,-2.453,1.123,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.0495842,0.00443048,0.992573 kka2_1:8_D52R,kka2_1:8_52,Kka2,kka2_1:8,P00552,0.992573,NO,52,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.271,-3.572,1.301,,0.22,E,B,0.75,0.8,5.447,,71.59,PAH,-2.38367,0.100394,0.00175694,0.992573 kka2_1:8_D52R,kka2_1:8_52,Kka2,kka2_1:8,P00552,0.992573,NO,52,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.271,-3.572,1.301,,0.22,E,B,0.75,0.8,5.447,,71.59,PAH,-2.38367,0.100394,0.00175694,0.992573 beta-lactamase_156_P181V,beta-lactamase_156_181,TEM-1,beta-lactamase_156,P62593,0.992575,NO,181,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.813,-3.492,2.679,,,H,A,0.52,-1.14,1.078,,61.54,HOH,-1.795,0.111618,0.000703122,0.992575 beta-lactamase_625_T112C,beta-lactamase_625_112,TEM-1,beta-lactamase_625,P62593,0.992579,NO,112,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.186,-5.027,2.841,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.213352,0.00531334,0.992579 beta-lactamase_39_T193N,beta-lactamase_39_193,TEM-1,beta-lactamase_39,P62593,0.99258,NO,193,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.914,-2.715,0.801,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.0495842,0.00482669,0.99258 beta-lactamase_2500_D207M,beta-lactamase_2500_207,TEM-1,beta-lactamase_2500,P62593,0.992587,NO,207,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.064,-4.822,2.758,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.361275,0.00592942,0.992587 beta-lactamase_625_L47S,beta-lactamase_625_47,TEM-1,beta-lactamase_625,P62593,0.992589,NO,47,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.876,-3.642,1.766,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.213352,0.00439844,0.992589 gb1_K236D,gb1_236,gb1,gb1,P06654,0.992591,NO,236,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-2.119,-3.174,1.055,,,,,,,1.083,,45.54,OBP,-1.758,0.177985,0.00255408,0.992591 beta-lactamase_0_S51Y,beta-lactamase_0_51,TEM-1,beta-lactamase_0,P62593,0.992594,NO,51,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.526,-4.345,2.819,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.0500837,0.00504821,0.992594 beta-lactamase_39_M270E,beta-lactamase_39_270,TEM-1,beta-lactamase_39,P62593,0.992594,NO,270,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.723,-4.709,2.986,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.0495842,0.00767762,0.992594 beta-lactamase_625_R59Q,beta-lactamase_625_59,TEM-1,beta-lactamase_625,P62593,0.992598,NO,59,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.345,-2.612,1.267,,0.329,S,L,1.2,-0.09,2.995,,73.08,HBO,-2.24267,0.213352,0.00318082,0.992598 beta-lactamase_2500_K213Q,beta-lactamase_2500_213,TEM-1,beta-lactamase_2500,P62593,0.992599,NO,213,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.81,-2.028,0.218,,0.67,,A,2.34,0.29,1.668,,67.83,ABH,-1.57767,0.361275,0.00610411,0.992599 beta-lactamase_625_H24E,beta-lactamase_625_24,TEM-1,beta-lactamase_625,P62593,0.9926,NO,24,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-2.481,-3.284,0.803,,,,,,,2.708,,93.01,OBO,-2.0035,0.213352,0.00238894,0.9926 beta-lactamase_39_Q37Y,beta-lactamase_39_37,TEM-1,beta-lactamase_39,P62593,0.99261,NO,37,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.134,-4.193,2.059,,0.613,H,A,0.64,1.98,22.282,22.282,73.08,APH,-2.06967,0.0495842,0.00425833,0.99261 beta-lactamase_2500_S256R,beta-lactamase_2500_256,TEM-1,beta-lactamase_2500,P62593,0.992611,NO,256,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.361275,0.00710634,0.992611 beta-lactamase_625_F149E,beta-lactamase_625_149,TEM-1,beta-lactamase_625,P62593,0.992612,NO,149,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.299,-3.842,2.543,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.213352,0.00418462,0.992612 beta-lactamase_625_Q203H,beta-lactamase_625_203,TEM-1,beta-lactamase_625,P62593,0.992616,NO,203,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.168,-4.663,2.495,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.213352,0.00631514,0.992616 beta-lactamase_625_E175Y,beta-lactamase_625_175,TEM-1,beta-lactamase_625,P62593,0.992618,NO,175,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.336,-4.303,1.967,,0.551,,A,1.04,1.05,8.527,8.527,77.62,AAB,-1.31233,0.213352,0.00482205,0.992618 beta-lactamase_156_T269K,beta-lactamase_156_269,TEM-1,beta-lactamase_156,P62593,0.992619,NO,269,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.111618,0.00950944,0.992619 beta-lactamase_625_G265H,beta-lactamase_625_265,TEM-1,beta-lactamase_625,P62593,0.99262,NO,265,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.213352,0.00811926,0.99262 beta-lactamase_625_E61C,beta-lactamase_625_61,TEM-1,beta-lactamase_625,P62593,0.992625,NO,61,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.115,-5.186,3.071,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.213352,0.00440955,0.992625 beta-lactamase_625_V82F,beta-lactamase_625_82,TEM-1,beta-lactamase_625,P62593,0.992631,NO,82,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.325,-3.991,2.666,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.213352,0.00397046,0.992631 beta-lactamase_625_A225R,beta-lactamase_625_225,TEM-1,beta-lactamase_625,P62593,0.992633,NO,225,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.845,-2.864,1.019,,1,T,B,0.46,-0.38,9.874,9.874,74.48,OHO,-1.39967,0.213352,0.00465057,0.992633 Pab1_E195N,Pab1_195,Pab1,Pab1,P04147,0.992635,NO,195,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.2,-3.318,2.118,,,,,,,,,,PAH,-1.72467,0.175299,0.000620107,0.992635 beta-lactamase_2500_A225D,beta-lactamase_2500_225,TEM-1,beta-lactamase_2500,P62593,0.992636,NO,225,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.845,-2.561,0.716,,1,T,B,0.46,-0.38,0.551,,74.48,OHO,-1.39967,0.361275,0.00465057,0.992636 beta-lactamase_0_I258W,beta-lactamase_0_258,TEM-1,beta-lactamase_0,P62593,0.992642,NO,258,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.0500837,0.007931,0.992642 beta-lactamase_0_T264W,beta-lactamase_0_264,TEM-1,beta-lactamase_0,P62593,0.992644,NO,264,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.0500837,0.0119399,0.992644 beta-lactamase_625_S96T,beta-lactamase_625_96,TEM-1,beta-lactamase_625,P62593,0.992644,NO,96,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.27,-2.436,0.166,,0.368,,b,0.27,0.39,5.244,,73.78,HPP,-2.019,0.213352,0.00551835,0.992644 beta-lactamase_156_G76A,beta-lactamase_156_76,TEM-1,beta-lactamase_156,P62593,0.992646,NO,76,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.189,-1.531,0.342,,,H,A,0.29,-0.67,3.059,,67.83,OOH,-1.22267,0.111618,0.00476637,0.992646 beta-lactamase_39_E102K,beta-lactamase_39_102,TEM-1,beta-lactamase_39,P62593,0.992646,NO,102,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.118,-2.64,0.522,,0.722,S,B,1.04,1.82,3.87,,73.08,HAH,-1.581,0.0495842,0.00486633,0.992646 beta-lactamase_39_V214C,beta-lactamase_39_214,TEM-1,beta-lactamase_39,P62593,0.992646,NO,214,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.299,-4.725,3.426,,0.375,S,A,0.44,-0.44,18.838,18.838,74.48,BHH,-1.53733,0.0495842,0.00628442,0.992646 beta-lactamase_625_P217I,beta-lactamase_625_217,TEM-1,beta-lactamase_625,P62593,0.992647,NO,217,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-2.062,-4.071,2.009,,0.496,I,A,0.52,-0.33,1.087,,74.48,OOH,-1.64333,0.213352,0.00463211,0.992647 beta-lactamase_625_G265A,beta-lactamase_625_265,TEM-1,beta-lactamase_625,P62593,0.992649,NO,265,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.213352,0.00811926,0.992649 beta-lactamase_2500_Q86W,beta-lactamase_2500_86,TEM-1,beta-lactamase_2500,P62593,0.992651,NO,86,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.4,-5.489,3.089,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.361275,0.00450027,0.992651 beta-lactamase_156_N173F,beta-lactamase_156_173,TEM-1,beta-lactamase_156,P62593,0.992653,NO,173,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-2.663,-4.355,1.692,,1.044,T,l,0.61,1.25,3.718,,77.62,OPA,-1.46633,0.111618,0.0033769,0.992653 beta-lactamase_625_A247T,beta-lactamase_625_247,TEM-1,beta-lactamase_625,P62593,0.992653,NO,247,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.213352,0.00611275,0.992653 beta-lactamase_2500_H151L,beta-lactamase_2500_151,TEM-1,beta-lactamase_2500,P62593,0.992659,NO,151,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-2.96,-3.494,0.534,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.361275,0.00216946,0.992659 beta-lactamase_156_V101T,beta-lactamase_156_101,TEM-1,beta-lactamase_156,P62593,0.99266,NO,101,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.295,-3.446,2.151,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.111618,0.00374492,0.99266 beta-lactamase_39_A278S,beta-lactamase_39_278,TEM-1,beta-lactamase_39,P62593,0.992663,NO,278,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.0495842,0.0310297,0.992663 beta-lactamase_625_T116S,beta-lactamase_625_116,TEM-1,beta-lactamase_625,P62593,0.992663,NO,116,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.28,-1.932,0.652,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.213352,0.00336175,0.992663 beta-lactamase_625_E175N,beta-lactamase_625_175,TEM-1,beta-lactamase_625,P62593,0.992667,NO,175,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.336,-3.857,1.521,,0.551,,A,1.04,1.05,8.527,8.527,77.62,AAB,-1.31233,0.213352,0.00482205,0.992667 beta-lactamase_625_S122C,beta-lactamase_625_122,TEM-1,beta-lactamase_625,P62593,0.992667,NO,122,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.406,-5.091,2.685,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.213352,0.00497825,0.992667 beta-lactamase_A84E,beta-lactamase_84,TEM-1,beta-lactamase,P62593,0.992667,NO,84,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.651,-2.632,0.981,5.28927,0.65,T,A,0.52,0.96,1.863,,68.18,AHO,-1.24267,0.221079,0.00503822,0.992667 beta-lactamase_E237C,beta-lactamase_237,TEM-1,beta-lactamase,P62593,0.992667,NO,237,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.058,-5.152,3.094,5.42877,0.583,S,B,1.62,1.2,2.144,,77.62,OAB,-1.61467,0.221079,0.0048626,0.992667 beta-lactamase_625_L47Y,beta-lactamase_625_47,TEM-1,beta-lactamase_625,P62593,0.992668,NO,47,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.876,-3.117,1.241,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.213352,0.00439844,0.992668 beta-lactamase_156_R159Y,beta-lactamase_156_159,TEM-1,beta-lactamase_156,P62593,0.992669,NO,159,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-0.94,-4.035,3.095,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.111618,0.00108472,0.992669 kka2_1:2_D154Q,kka2_1:2_154,Kka2,kka2_1:2,P00552,0.992672,NO,154,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.876,-3.709,2.833,,0.457,,b,0.29,1.48,3.631,,52.65,HAP,-1.52467,0.295029,0.00292633,0.992672 beta-lactamase_156_S256Y,beta-lactamase_156_256,TEM-1,beta-lactamase_156,P62593,0.992674,NO,256,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.111618,0.00710634,0.992674 beta-lactamase_2500_T269G,beta-lactamase_2500_269,TEM-1,beta-lactamase_2500,P62593,0.992676,NO,269,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.361275,0.00950944,0.992676 beta-lactamase_156_G52F,beta-lactamase_156_52,TEM-1,beta-lactamase_156,P62593,0.992677,NO,52,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.149,-4.393,3.244,,0.299,,l,0.29,-0.04,1.179,,64.69,POB,-1.66267,0.111618,0.00340138,0.992677 Pab1_A178T,Pab1_178,Pab1,Pab1,P04147,0.992684,NO,178,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.579,-3.178,1.599,,0.019,H,A,0.64,0.64,2.7,,81.63,OHH,-1.61067,0.175299,0.00160192,0.992684 beta-lactamase_39_T139E,beta-lactamase_39_139,TEM-1,beta-lactamase_39,P62593,0.992687,NO,139,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.901,-2.44,0.539,,0.216,H,A,0.22,0.39,0.421,,77.62,PPH,-2.04667,0.0495842,0.00441837,0.992687 beta-lactamase_156_A222E,beta-lactamase_156_222,TEM-1,beta-lactamase_156,P62593,0.992695,NO,222,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.103,-3.646,1.543,,0.233,H,A,0.46,-0.25,2.461,,77.62,PHH,-1.63733,0.111618,0.00466094,0.992695 beta-lactamase_2500_N152H,beta-lactamase_2500_152,TEM-1,beta-lactamase_2500,P62593,0.992699,NO,152,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-2.757,-3.372,0.615,,0.863,H,A,0.61,0.92,2.061,,77.62,BPH,-2.97,0.361275,0.00471429,0.992699 beta-lactamase_625_D207L,beta-lactamase_625_207,TEM-1,beta-lactamase_625,P62593,0.992706,NO,207,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.064,-3.704,1.64,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.213352,0.00592942,0.992706 beta-lactamase_39_K53S,beta-lactamase_39_53,TEM-1,beta-lactamase_39,P62593,0.992708,NO,53,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-2.313,-2.879,0.566,,0.589,,B,2.34,1.15,15.633,15.633,77.62,OBH,-2.1,0.0495842,0.00383383,0.992708 beta-lactamase_625_T147E,beta-lactamase_625_147,TEM-1,beta-lactamase_625,P62593,0.992715,NO,147,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.149,-3.519,2.37,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.213352,0.00226017,0.992715 beta-lactamase_625_R118H,beta-lactamase_625_118,TEM-1,beta-lactamase_625,P62593,0.992717,NO,118,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.413,-4.71,2.297,,0.457,H,A,1.2,1.39,2.144,,77.62,HBA,-1.785,0.213352,0.00538794,0.992717 beta-lactamase_156_N173D,beta-lactamase_156_173,TEM-1,beta-lactamase_156,P62593,0.992724,NO,173,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-2.663,-2.368,-0.295,,1.044,T,l,0.61,1.25,3.718,,77.62,OPA,-1.46633,0.111618,0.0033769,0.992724 beta-lactamase_2500_A84G,beta-lactamase_2500_84,TEM-1,beta-lactamase_2500,P62593,0.992725,NO,84,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.651,-3.358,1.707,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.361275,0.00503822,0.992725 beta-lactamase_625_T198Y,beta-lactamase_625_198,TEM-1,beta-lactamase_625,P62593,0.992731,NO,198,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.168,-4.211,2.043,,0.489,,B,0.22,-0.13,0.37,,73.78,HPH,-1.98767,0.213352,0.004311,0.992731 beta-lactamase_625_A211C,beta-lactamase_625_211,TEM-1,beta-lactamase_625,P62593,0.992735,NO,211,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.896,-5.066,3.17,,0.369,T,A,0.46,-0.69,2.061,,77.62,AHA,-1.94633,0.213352,0.00648183,0.992735 beta-lactamase_39_N173G,beta-lactamase_39_173,TEM-1,beta-lactamase_39,P62593,0.992741,NO,173,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-2.663,-1.002,-1.661,,1.044,T,l,0.61,1.25,1.426,,77.62,OPA,-1.46633,0.0495842,0.0033769,0.992741 beta-lactamase_156_K286N,beta-lactamase_156_286,TEM-1,beta-lactamase_156,P62593,0.992742,NO,286,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.111618,,0.992742 beta-lactamase_156_A246L,beta-lactamase_156_246,TEM-1,beta-lactamase_156,P62593,0.992749,NO,246,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.121,-1.908,-0.213,,0.01,E,B,0.46,-1.01,1.959,,73.78,HHH,-1.55633,0.111618,0.00569458,0.992749 beta-lactamase_625_G85A,beta-lactamase_625_85,TEM-1,beta-lactamase_625,P62593,0.992749,NO,85,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.011,-3.043,2.032,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.213352,0.00252173,0.992749 beta-lactamase_39_S256M,beta-lactamase_39_256,TEM-1,beta-lactamase_39,P62593,0.992751,NO,256,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.0495842,0.00710634,0.992751 beta-lactamase_G226N,beta-lactamase_226,TEM-1,beta-lactamase,P62593,0.992752,NO,226,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.461,-2.628,1.167,5.70682,0.701,T,l,0.77,-0.25,3.199,,74.48,HOH,-1.42933,0.221079,0.00665294,0.992752 beta-lactamase_P12W,beta-lactamase_12,TEM-1,beta-lactamase,P62593,0.992752,NO,12,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-2.016,-5.127,3.111,,,,,,,2.88,,72.73,HOH,-2.05167,0.221079,0.00241653,0.992752 gb1_K276N,gb1_276,gb1,gb1,P06654,0.992759,NO,276,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.456,-3.288,1.832,,,,,,,0.236,,12.72,PBP,-1.65133,0.177985,0.00620493,0.992759 beta-lactamase_625_A170H,beta-lactamase_625_170,TEM-1,beta-lactamase_625,P62593,0.992762,NO,170,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.237,-4.694,3.457,,0.126,,L,0.46,-0.35,3.626,,64.69,AHH,-1.63267,0.213352,0.00431903,0.992762 beta-lactamase_156_S96H,beta-lactamase_156_96,TEM-1,beta-lactamase_156,P62593,0.992764,NO,96,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.27,-3.418,1.148,,0.368,,b,0.27,0.39,2.838,,73.78,HPP,-2.019,0.111618,0.00551835,0.992764 beta-lactamase_39_A247S,beta-lactamase_39_247,TEM-1,beta-lactamase_39,P62593,0.992768,NO,247,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.0495842,0.00611275,0.992768 beta-lactamase_2500_N173F,beta-lactamase_2500_173,TEM-1,beta-lactamase_2500,P62593,0.992769,NO,173,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-2.663,-4.355,1.692,,1.044,T,l,0.61,1.25,1.88,,77.62,OPA,-1.46633,0.361275,0.0033769,0.992769 beta-lactamase_0_T264R,beta-lactamase_0_264,TEM-1,beta-lactamase_0,P62593,0.992772,NO,264,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.0500837,0.0119399,0.992772 beta-lactamase_625_T264Q,beta-lactamase_625_264,TEM-1,beta-lactamase_625,P62593,0.992773,NO,264,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.213352,0.0119399,0.992773 beta-lactamase_156_L192C,beta-lactamase_156_192,TEM-1,beta-lactamase_156,P62593,0.992777,NO,192,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.254,-4.743,3.489,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.111618,0.00558728,0.992777 WW_domain_A175Q,WW_domain_175,Yap65,WW_domain,P46937,0.992781,NO,175,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.631,-3.759,2.128,6.69537,,,,,,6.257,,83.93,OHO,-1.30033,0.153962,0.00326874,0.992781 beta-lactamase_156_G236S,beta-lactamase_156_236,TEM-1,beta-lactamase_156,P62593,0.992782,NO,236,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.784,-2.475,1.691,,0.241,,b,0.29,-0.59,1.883,,64.69,HOO,-1.025,0.111618,0.00162372,0.992782 beta-lactamase_156_P143A,beta-lactamase_156_143,TEM-1,beta-lactamase_156,P62593,0.992786,NO,143,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.967,-3.126,2.159,,0.075,H,A,0.52,-0.37,0.479,,66.78,OOB,-1.354,0.111618,0.00114551,0.992786 beta-lactamase_625_G194W,beta-lactamase_625_194,TEM-1,beta-lactamase_625,P62593,0.992786,NO,194,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.396,-5.42,4.024,,0.276,S,b,0.29,0.36,3.593,,67.83,POA,-1.832,0.213352,0.00392163,0.992786 beta-lactamase_625_H287S,beta-lactamase_625_287,TEM-1,beta-lactamase_625,P62593,0.992789,NO,287,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,,,,,,,,,,,,,BBH,-1.111,0.213352,,0.992789 beta-lactamase_625_L196K,beta-lactamase_625_196,TEM-1,beta-lactamase_625,P62593,0.992789,NO,196,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-2.478,-3.633,1.155,,0.518,S,A,0.55,1.35,12.152,12.152,77.62,AHH,-1.839,0.213352,0.00512144,0.992789 beta-lactamase_625_S57G,beta-lactamase_625_57,TEM-1,beta-lactamase_625,P62593,0.992793,NO,57,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.918,-2.176,0.258,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.213352,0.00492804,0.992793 beta-lactamase_156_V117N,beta-lactamase_156_117,TEM-1,beta-lactamase_156,P62593,0.992797,NO,117,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.53,-4.224,2.694,,,H,A,0.44,-0.34,1.182,,65.03,PHB,-1.741,0.111618,0.00467906,0.992797 beta-lactamase_39_W288R,beta-lactamase_39_288,TEM-1,beta-lactamase_39,P62593,0.992799,NO,288,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,,,,,,,,,,,,,BHO,,0.0495842,,0.992799 beta-lactamase_156_H287R,beta-lactamase_156_287,TEM-1,beta-lactamase_156,P62593,0.992809,NO,287,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,,,,,,,,,,,,,BBH,-1.111,0.111618,,0.992809 beta-lactamase_625_D271N,beta-lactamase_625_271,TEM-1,beta-lactamase_625,P62593,0.992809,NO,271,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.213352,0.00752082,0.992809 beta-lactamase_0_V157D,beta-lactamase_0_157,TEM-1,beta-lactamase_0,P62593,0.992811,NO,157,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.751,-3.908,2.157,,0.308,S,a,0.44,-0.75,3.106,,69.58,BHP,-2.00767,0.0500837,0.00506849,0.992811 beta-lactamase_E166K,beta-lactamase_166,TEM-1,beta-lactamase,P62593,0.992811,NO,166,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.756,-2.625,0.869,5.60527,0.508,G,A,0.52,1.05,2.124,,73.08,OAH,-1.42233,0.221079,0.00512989,0.992811 beta-lactamase_625_T139K,beta-lactamase_625_139,TEM-1,beta-lactamase_625,P62593,0.992813,NO,139,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.901,-3.403,1.502,,0.216,H,A,0.22,0.39,2.256,,77.62,PPH,-2.04667,0.213352,0.00441837,0.992813 beta-lactamase_2500_R118M,beta-lactamase_2500_118,TEM-1,beta-lactamase_2500,P62593,0.992821,NO,118,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.413,-4.747,2.334,,0.457,H,A,1.2,1.39,2.144,,77.62,HBA,-1.785,0.361275,0.00538794,0.992821 beta-lactamase_156_L188H,beta-lactamase_156_188,TEM-1,beta-lactamase_156,P62593,0.992824,NO,188,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.166,-4.872,3.706,,,H,A,0.55,-0.3,1.574,,60.14,PHB,-1.47033,0.111618,0.00295687,0.992824 beta-lactamase_39_S266I,beta-lactamase_39_266,TEM-1,beta-lactamase_39,P62593,0.992824,NO,266,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.0495842,0.0140785,0.992824 beta-lactamase_39_T263F,beta-lactamase_39_263,TEM-1,beta-lactamase_39,P62593,0.992825,NO,263,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.0495842,0.0110582,0.992825 beta-lactamase_39_G90P,beta-lactamase_39_90,TEM-1,beta-lactamase_39,P62593,0.992828,NO,90,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-2.091,-3.952,1.861,,0.598,T,A,0.29,0.32,30.794,30.794,77.62,HOB,-1.52633,0.0495842,0.00490273,0.992828 beta-lactamase_2500_R159H,beta-lactamase_2500_159,TEM-1,beta-lactamase_2500,P62593,0.992831,NO,159,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-0.94,-2.789,1.849,,0.316,,B,1.2,-0.55,2.341,,64.34,PBH,-1.011,0.361275,0.00108472,0.992831 beta-lactamase_625_G39K,beta-lactamase_625_39,TEM-1,beta-lactamase_625,P62593,0.992832,NO,39,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.864,-2.703,0.839,,0.701,T,L,0.29,0.47,29.926,29.926,77.62,HOH,-1.53633,0.213352,0.00487611,0.992832 beta-lactamase_156_N98I,beta-lactamase_156_98,TEM-1,beta-lactamase_156,P62593,0.99284,NO,98,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-2.973,-4.064,1.091,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.111618,0.00505389,0.99284 beta-lactamase_39_A230V,beta-lactamase_39_230,TEM-1,beta-lactamase_39,P62593,0.992842,NO,230,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.154,-3.38,2.226,,0.01,E,B,0.46,-1.17,1.171,,50,HHA,-1.079,0.0495842,0.00516841,0.992842 beta-lactamase_156_L38T,beta-lactamase_156_38,TEM-1,beta-lactamase_156,P62593,0.992844,NO,38,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.343,-3.495,2.152,,0.088,H,A,0.55,0.2,13.556,13.556,64.34,PHO,-1.78033,0.111618,0.00373244,0.992844 beta-lactamase_156_P60Y,beta-lactamase_156_60,TEM-1,beta-lactamase_156,P62593,0.992846,NO,60,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-2.469,-4.292,1.823,,0.256,T,A,0.52,-0.56,2.947,,77.62,BOA,-1.97633,0.111618,0.00521318,0.992846 beta-lactamase_625_A225E,beta-lactamase_625_225,TEM-1,beta-lactamase_625,P62593,0.992854,NO,225,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.845,-2.246,0.401,,1,T,B,0.46,-0.38,9.874,9.874,74.48,OHO,-1.39967,0.213352,0.00465057,0.992854 beta-lactamase_156_L136A,beta-lactamase_156_136,TEM-1,beta-lactamase_156,P62593,0.992855,NO,136,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.232,-3.144,1.912,,,H,A,0.55,-0.34,1.04,,48.95,HHH,-1.088,0.111618,0.00442304,0.992855 beta-lactamase_39_R239G,beta-lactamase_39_239,TEM-1,beta-lactamase_39,P62593,0.992859,NO,239,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-0.819,-3.876,3.057,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.0495842,0.00213852,0.992859 kka2_1:8_P179G,kka2_1:8_179,Kka2,kka2_1:8,P00552,0.992859,NO,179,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.974,-3.438,2.464,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.100394,0.00298346,0.992859 kka2_1:8_P179G,kka2_1:8_179,Kka2,kka2_1:8,P00552,0.992859,NO,179,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.974,-3.438,2.464,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.100394,0.00298346,0.992859 beta-lactamase_156_L55A,beta-lactamase_156_55,TEM-1,beta-lactamase_156,P62593,0.992862,NO,55,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.86,-2.512,0.652,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.111618,0.00403741,0.992862 beta-lactamase_625_P224T,beta-lactamase_625_224,TEM-1,beta-lactamase_625,P62593,0.992863,NO,224,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.893,-3.414,2.521,,0.383,,B,0.52,-0.3,1.35,,74.48,HOH,-1.26433,0.213352,0.00189564,0.992863 beta-lactamase_156_L137T,beta-lactamase_156_137,TEM-1,beta-lactamase_156,P62593,0.992865,NO,137,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.03,-3.486,2.456,,,H,A,0.55,-0.38,0.674,,42.31,HHP,-1.58933,0.111618,0.00278599,0.992865 beta-lactamase_625_L137Y,beta-lactamase_625_137,TEM-1,beta-lactamase_625,P62593,0.992868,NO,137,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.03,-4.002,2.972,,,H,A,0.55,-0.38,1.5,,42.31,HHP,-1.58933,0.213352,0.00278599,0.992868 beta-lactamase_156_D174E,beta-lactamase_156_174,TEM-1,beta-lactamase_156,P62593,0.992872,NO,174,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.738,-2.765,2.027,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.111618,0.00125633,0.992872 beta-lactamase_156_K30H,beta-lactamase_156_30,TEM-1,beta-lactamase_156,P62593,0.992873,NO,30,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-2.307,-4.558,2.251,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.111618,0.00448593,0.992873 beta-lactamase_156_L111I,beta-lactamase_156_111,TEM-1,beta-lactamase_156,P62593,0.992875,NO,111,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.76,-2.153,0.393,,0.328,T,A,0.55,0.93,2.26,,64.34,BHP,-1.884,0.111618,0.00480671,0.992875 beta-lactamase_625_E87W,beta-lactamase_625_87,TEM-1,beta-lactamase_625,P62593,0.992877,NO,87,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.421,-5.437,4.016,,0.048,,B,1.04,0.92,17.923,17.923,64.69,PAP,-1.969,0.213352,0.00337888,0.992877 beta-lactamase_A84H,beta-lactamase_84,TEM-1,beta-lactamase,P62593,0.992887,NO,84,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.651,-3.344,1.693,5.28927,0.65,T,A,0.52,0.96,1.863,,68.18,AHO,-1.24267,0.221079,0.00503822,0.992887 beta-lactamase_P217D,beta-lactamase_217,TEM-1,beta-lactamase,P62593,0.992887,NO,217,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-2.062,-2.498,0.436,5.19872,0.496,I,A,0.99,-0.33,0.431,,74.48,OOH,-1.64333,0.221079,0.00463211,0.992887 beta-lactamase_Q204A,beta-lactamase_204,TEM-1,beta-lactamase,P62593,0.992887,NO,204,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-1.382,-2.589,1.207,5.46394,0.204,H,A,0.12,0.09,1.707,,66.08,PPH,-1.49067,0.221079,0.00364106,0.992887 beta-lactamase_T261I,beta-lactamase_261,TEM-1,beta-lactamase,P62593,0.992887,NO,261,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.88,-1.929,-0.951,5.65483,0.014,E,B,0.53,-0.39,2.449,,77.62,HPP,-1.771,0.221079,0.0123091,0.992887 beta-lactamase_V157E,beta-lactamase_157,TEM-1,beta-lactamase,P62593,0.992887,NO,157,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.751,-3.68,1.929,5.51733,0.308,S,a,0.96,-0.75,1.847,,69.58,BHP,-2.00767,0.221079,0.00506849,0.992887 beta-lactamase_625_P250L,beta-lactamase_625_250,TEM-1,beta-lactamase_625,P62593,0.992888,NO,250,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.213352,0.00550899,0.992888 beta-lactamase_39_R81E,beta-lactamase_39_81,TEM-1,beta-lactamase_39,P62593,0.992889,NO,81,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.466,-2.677,1.211,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.0495842,0.00499763,0.992889 beta-lactamase_156_A200W,beta-lactamase_156_200,TEM-1,beta-lactamase_156,P62593,0.992891,NO,200,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.878,-5.525,3.647,,0.757,H,A,0.46,-0.19,16.368,16.368,77.62,HHP,-2.001,0.111618,0.0060056,0.992891 beta-lactamase_2500_D207A,beta-lactamase_2500_207,TEM-1,beta-lactamase_2500,P62593,0.992891,NO,207,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.064,-2.585,0.521,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.361275,0.00592942,0.992891 beta-lactamase_625_A246S,beta-lactamase_625_246,TEM-1,beta-lactamase_625,P62593,0.992891,NO,246,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.121,-3.607,1.486,,0.01,E,B,0.46,-1.01,1.201,,73.78,HHH,-1.55633,0.213352,0.00569458,0.992891 beta-lactamase_625_S57N,beta-lactamase_625_57,TEM-1,beta-lactamase_625,P62593,0.992891,NO,57,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.918,-2.953,1.035,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.213352,0.00492804,0.992891 PSD95pdz3_L379C,PSD95pdz3_379,PSD95pdz3,PSD95pdz3,P31016,0.992894,NO,379,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.347,-4.319,2.972,5.37777,,,,,16.8762,,,,HHB,-1.35667,0.0758425,0.00029733,0.992894 beta-lactamase_39_M67Q,beta-lactamase_39_67,TEM-1,beta-lactamase_39,P62593,0.992897,NO,67,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-2.231,-4.09,1.859,,0.006,G,P,0.55,-0.81,1.463,,65.03,HHP,-1.502,0.0495842,0.00409753,0.992897 beta-lactamase_625_L55T,beta-lactamase_625_55,TEM-1,beta-lactamase_625,P62593,0.992907,NO,55,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.86,-3.617,1.757,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.213352,0.00403741,0.992907 beta-lactamase_625_R176G,beta-lactamase_625_176,TEM-1,beta-lactamase_625,P62593,0.992911,NO,176,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-0.863,-3.358,2.495,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.213352,0.00105554,0.992911 beta-lactamase_625_R41M,beta-lactamase_625_41,TEM-1,beta-lactamase_625,P62593,0.992917,NO,41,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-0.942,-4.506,3.564,,0.321,E,B,1.2,-0.07,1.186,,65.03,HBH,-1.30267,0.213352,0.00123327,0.992917 beta-lactamase_39_V101T,beta-lactamase_39_101,TEM-1,beta-lactamase_39,P62593,0.992923,NO,101,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.295,-3.446,2.151,,0.342,,B,0.44,0,2.96,,73.08,HHA,-1.54367,0.0495842,0.00374492,0.992923 beta-lactamase_625_G253P,beta-lactamase_625_253,TEM-1,beta-lactamase_625,P62593,0.992928,NO,253,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-2.253,-2.791,0.538,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.213352,0.00786358,0.992928 beta-lactamase_156_Q97T,beta-lactamase_156_97,TEM-1,beta-lactamase_156,P62593,0.992931,NO,97,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.072,-2.713,0.641,,0.823,G,A,0.64,2.42,4.457,,77.62,PPP,-2.43833,0.111618,0.0045116,0.992931 beta-lactamase_39_V82M,beta-lactamase_39_82,TEM-1,beta-lactamase_39,P62593,0.992931,NO,82,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.325,-4.274,2.949,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.0495842,0.00397046,0.992931 beta-lactamase_156_P217S,beta-lactamase_156_217,TEM-1,beta-lactamase_156,P62593,0.992933,NO,217,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-2.062,-2.615,0.553,,0.496,I,A,0.52,-0.33,2.303,,74.48,OOH,-1.64333,0.111618,0.00463211,0.992933 beta-lactamase_2500_A230G,beta-lactamase_2500_230,TEM-1,beta-lactamase_2500,P62593,0.992933,NO,230,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.154,-1.479,0.325,,0.01,E,B,0.46,-1.17,1.171,,50,HHA,-1.079,0.361275,0.00516841,0.992933 beta-lactamase_625_V31I,beta-lactamase_625_31,TEM-1,beta-lactamase_625,P62593,0.992933,NO,31,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.822,-1.838,0.016,,,H,A,0.44,-0.46,2.576,,73.78,BHB,-2.03767,0.213352,0.00478065,0.992933 beta-lactamase_156_H156R,beta-lactamase_156_156,TEM-1,beta-lactamase_156,P62593,0.992937,NO,156,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-3.156,-2.742,-0.414,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.111618,0.00468596,0.992937 beta-lactamase_Q265V,beta-lactamase_265,TEM-1,beta-lactamase,P62593,0.992941,NO,265,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.58,-3.717,1.137,6.62674,1.116,,A,0.03,1.17,12.514,12.514,69.58,PPH,-1.978,0.221079,0.00811926,0.992941 beta-lactamase_156_D83T,beta-lactamase_156_83,TEM-1,beta-lactamase_156,P62593,0.992948,NO,83,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.066,-3.464,2.398,,0.354,H,A,0.75,0.22,1.281,,48.95,HAH,-1.34733,0.111618,0.00205968,0.992948 beta-lactamase_39_L100G,beta-lactamase_39_100,TEM-1,beta-lactamase_39,P62593,0.992951,NO,100,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.218,-3.854,2.636,,0.343,,B,0.55,0.13,8.311,,63.29,AHH,-1.23467,0.0495842,0.00413885,0.992951 beta-lactamase_39_A268D,beta-lactamase_39_268,TEM-1,beta-lactamase_39,P62593,0.992963,NO,268,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.0495842,0.0102525,0.992963 beta-lactamase_625_P143C,beta-lactamase_625_143,TEM-1,beta-lactamase_625,P62593,0.992963,NO,143,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.967,-5.012,4.045,,0.075,H,A,0.52,-0.37,1.445,,66.78,OOB,-1.354,0.213352,0.00114551,0.992963 beta-lactamase_39_H24E,beta-lactamase_39_24,TEM-1,beta-lactamase_39,P62593,0.992966,NO,24,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-2.481,-3.284,0.803,,,,,,,2.708,,93.01,OBO,-2.0035,0.0495842,0.00238894,0.992966 kka2_1:1_I2Q,kka2_1:1_2,Kka2,kka2_1:1,P00552,0.992967,NO,2,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.787,-3.979,2.192,,,,,,,2.329,,71.59,HHA,-1.92433,0.520039,0.00246644,0.992967 beta-lactamase_156_L137W,beta-lactamase_156_137,TEM-1,beta-lactamase_156,P62593,0.992968,NO,137,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.03,-5.164,4.134,,,H,A,0.55,-0.38,0.674,,42.31,HHP,-1.58933,0.111618,0.00278599,0.992968 beta-lactamase_625_W163L,beta-lactamase_625_163,TEM-1,beta-lactamase_625,P62593,0.992968,NO,163,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-1.843,-2.838,0.995,,0.467,,B,0.47,-0.5,5.019,,63.99,BHA,-1.269,0.213352,0.00418955,0.992968 beta-lactamase_156_V82M,beta-lactamase_156_82,TEM-1,beta-lactamase_156,P62593,0.992975,NO,82,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.325,-4.274,2.949,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.111618,0.00397046,0.992975 beta-lactamase_625_S80I,beta-lactamase_625_80,TEM-1,beta-lactamase_625,P62593,0.992979,NO,80,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.029,-3.787,1.758,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.213352,0.00565569,0.992979 beta-lactamase_156_S266V,beta-lactamase_156_266,TEM-1,beta-lactamase_156,P62593,0.992981,NO,266,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.111618,0.0140785,0.992981 beta-lactamase_2500_E238W,beta-lactamase_2500_238,TEM-1,beta-lactamase_2500,P62593,0.992984,NO,238,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.361275,0.00743256,0.992984 beta-lactamase_39_P172L,beta-lactamase_39_172,TEM-1,beta-lactamase_39,P62593,0.992985,NO,172,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.998,-2.658,1.66,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.0495842,0.00312594,0.992985 beta-lactamase_625_R91Y,beta-lactamase_625_91,TEM-1,beta-lactamase_625,P62593,0.992988,NO,91,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.392,-4.246,2.854,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.213352,0.00380226,0.992988 beta-lactamase_D269N,beta-lactamase_269,TEM-1,beta-lactamase,P62593,0.992989,NO,269,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.156,-2.753,0.597,5.47645,0.646,H,A,0.23,0.4,21.796,21.796,77.62,HAA,-1.96733,0.221079,0.00950944,0.992989 beta-lactamase_E145C,beta-lactamase_145,TEM-1,beta-lactamase,P62593,0.992989,NO,145,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.357,-5.044,2.687,5.38104,0.545,H,A,0.52,0.79,2.124,,77.62,BAH,-2.069,0.221079,0.00553285,0.992989 beta-lactamase_I45L,beta-lactamase_45,TEM-1,beta-lactamase,P62593,0.992989,NO,45,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-2.421,-2.39,-0.031,5.31505,,E,B,1,-0.3,2.256,,77.62,HHA,-2.30267,0.221079,0.00452842,0.992989 beta-lactamase_625_T139N,beta-lactamase_625_139,TEM-1,beta-lactamase_625,P62593,0.992993,NO,139,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.901,-3.686,1.785,,0.216,H,A,0.22,0.39,2.256,,77.62,PPH,-2.04667,0.213352,0.00441837,0.992993 kka2_1:8_P179K,kka2_1:8_179,Kka2,kka2_1:8,P00552,0.992993,NO,179,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.974,-3.58,2.606,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.100394,0.00298346,0.992993 kka2_1:8_P179K,kka2_1:8_179,Kka2,kka2_1:8,P00552,0.992993,NO,179,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.974,-3.58,2.606,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.100394,0.00298346,0.992993 PSD95pdz3_G383E,PSD95pdz3_383,PSD95pdz3,PSD95pdz3,P31016,0.992999,NO,383,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.008,-3.347,2.339,5.17213,,,,,20.5325,,,,HOP,-1.338,0.0758425,0.000233044,0.992999 beta-lactamase_S96R,beta-lactamase_96,TEM-1,beta-lactamase,P62593,0.993002,NO,96,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.27,-2.133,-0.137,5.29889,0.368,,b,0.25,0.39,32.348,32.348,73.78,HPP,-2.019,0.221079,0.00551835,0.993002 beta-lactamase_39_L196W,beta-lactamase_39_196,TEM-1,beta-lactamase_39,P62593,0.993004,NO,196,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-2.478,-5.492,3.014,,0.518,S,A,0.55,1.35,12.152,12.152,77.62,AHH,-1.839,0.0495842,0.00512144,0.993004 beta-lactamase_39_A200W,beta-lactamase_39_200,TEM-1,beta-lactamase_39,P62593,0.993007,NO,200,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.878,-5.525,3.647,,0.757,H,A,0.46,-0.19,1.54,,77.62,HHP,-2.001,0.0495842,0.0060056,0.993007 beta-lactamase_39_G90Q,beta-lactamase_39_90,TEM-1,beta-lactamase_39,P62593,0.993007,NO,90,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-2.091,-2.862,0.771,,0.598,T,A,0.29,0.32,30.794,30.794,77.62,HOB,-1.52633,0.0495842,0.00490273,0.993007 beta-lactamase_156_E62V,beta-lactamase_156_62,TEM-1,beta-lactamase_156,P62593,0.993012,NO,62,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.193,-3.636,2.443,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.111618,0.00264802,0.993012 beta-lactamase_E61L,beta-lactamase_61,TEM-1,beta-lactamase,P62593,0.993014,NO,61,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.115,-3.769,1.654,6.29701,0.775,T,a,0.52,1.29,1.975,,77.62,OAA,-1.92567,0.221079,0.00440955,0.993014 beta-lactamase_N134N,beta-lactamase_134,TEM-1,beta-lactamase,P62593,0.993014,NO,134,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-0.879,-0.879,,5.07245,0.138,H,A,0.09,-0.6,1.441,,53.15,HPH,-1.02233,0.221079,0.000644786,0.993014 beta-lactamase_39_Q37I,beta-lactamase_39_37,TEM-1,beta-lactamase_39,P62593,0.993016,NO,37,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.134,-4.024,1.89,,0.613,H,A,0.64,1.98,22.282,22.282,73.08,APH,-2.06967,0.0495842,0.00425833,0.993016 beta-lactamase_39_N168C,beta-lactamase_39_168,TEM-1,beta-lactamase_39,P62593,0.993019,NO,168,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-1.029,-4.99,3.961,,0.113,G,A,0.61,-0.4,0.822,,44.41,HPA,-1.13233,0.0495842,0.00288667,0.993019 beta-lactamase_156_E175P,beta-lactamase_156_175,TEM-1,beta-lactamase_156,P62593,0.993023,NO,175,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.336,-1.972,-0.364,,0.551,,A,1.04,1.05,2.334,,77.62,AAB,-1.31233,0.111618,0.00482205,0.993023 beta-lactamase_156_E175L,beta-lactamase_156_175,TEM-1,beta-lactamase_156,P62593,0.993024,NO,175,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.336,-3.444,1.108,,0.551,,A,1.04,1.05,2.334,,77.62,AAB,-1.31233,0.111618,0.00482205,0.993024 beta-lactamase_625_L38G,beta-lactamase_625_38,TEM-1,beta-lactamase_625,P62593,0.993024,NO,38,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.343,-3.696,2.353,,0.088,H,A,0.55,0.2,1.986,,64.34,PHO,-1.78033,0.213352,0.00373244,0.993024 beta-lactamase_156_K32E,beta-lactamase_156_32,TEM-1,beta-lactamase_156,P62593,0.993026,NO,32,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.984,-2.418,0.434,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.111618,0.00401283,0.993026 beta-lactamase_156_T198H,beta-lactamase_156_198,TEM-1,beta-lactamase_156,P62593,0.993026,NO,198,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.168,-3.211,1.043,,0.489,,B,0.22,-0.13,10.771,10.771,73.78,HPH,-1.98767,0.111618,0.004311,0.993026 Pab1_D136C,Pab1_136,Pab1,Pab1,P04147,0.993026,NO,136,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.602,-4.63,3.028,,,,,,,,,,OAH,-1.42367,0.175299,0.00227029,0.993026 beta-lactamase_625_E175C,beta-lactamase_625_175,TEM-1,beta-lactamase_625,P62593,0.993032,NO,175,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.336,-5.076,2.74,,0.551,,A,1.04,1.05,8.527,8.527,77.62,AAB,-1.31233,0.213352,0.00482205,0.993032 beta-lactamase_156_P217A,beta-lactamase_156_217,TEM-1,beta-lactamase_156,P62593,0.993039,NO,217,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-2.062,-1.891,-0.171,,0.496,I,A,0.52,-0.33,2.303,,74.48,OOH,-1.64333,0.111618,0.00463211,0.993039 beta-lactamase_S96A,beta-lactamase_96,TEM-1,beta-lactamase,P62593,0.993039,NO,96,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.27,-2.75,0.48,5.29889,0.368,,b,0.25,0.39,32.348,32.348,73.78,HPP,-2.019,0.221079,0.00551835,0.993039 beta-lactamase_2500_N152L,beta-lactamase_2500_152,TEM-1,beta-lactamase_2500,P62593,0.993043,NO,152,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-2.757,-3.55,0.793,,0.863,H,A,0.61,0.92,2.061,,77.62,BPH,-2.97,0.361275,0.00471429,0.993043 beta-lactamase_A225L,beta-lactamase_225,TEM-1,beta-lactamase,P62593,0.993045,NO,225,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.845,-2.985,1.14,6.5181,1,T,B,0.58,-0.38,4.077,,74.48,OHO,-1.39967,0.221079,0.00465057,0.993045 kka2_1:4_H106N,kka2_1:4_106,Kka2,kka2_1:4,P00552,0.993053,NO,106,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-3.13,-3.028,-0.102,,1.065,.,a,0.17,-0.95,16.74,16.74,71.59,PBH,-2.10433,0.168804,0.00730778,0.993053 beta-lactamase_39_T116R,beta-lactamase_39_116,TEM-1,beta-lactamase_39,P62593,0.993054,NO,116,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.28,-2.627,1.347,,0.115,E,B,0.22,-0.12,1.133,,67.48,HPH,-1.39967,0.0495842,0.00336175,0.993054 beta-lactamase_625_E102P,beta-lactamase_625_102,TEM-1,beta-lactamase_625,P62593,0.993054,NO,102,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.118,-3.88,1.762,,0.722,S,B,1.04,1.82,1.336,,73.08,HAH,-1.581,0.213352,0.00486633,0.993054 beta-lactamase_156_T263G,beta-lactamase_156_263,TEM-1,beta-lactamase_156,P62593,0.993055,NO,263,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.031,-3.618,1.587,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.111618,0.0110582,0.993055 beta-lactamase_2500_L196K,beta-lactamase_2500_196,TEM-1,beta-lactamase_2500,P62593,0.993056,NO,196,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-2.478,-3.633,1.155,,0.518,S,A,0.55,1.35,7.897,,77.62,AHH,-1.839,0.361275,0.00512144,0.993056 beta-lactamase_39_G114D,beta-lactamase_39_114,TEM-1,beta-lactamase_39,P62593,0.993056,NO,114,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.094,-3.551,2.457,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.0495842,0.00224919,0.993056 Pab1_L190M,Pab1_190,Pab1,Pab1,P04147,0.993056,NO,190,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.325,-2.274,0.949,,0.489,E,B,,2.59,,,,HHH,-1.31033,0.175299,0.00132347,0.993056 beta-lactamase_2500_D113S,beta-lactamase_2500_113,TEM-1,beta-lactamase_2500,P62593,0.993057,NO,113,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.829,-2.84,1.011,,0.665,T,A,0.75,0.91,21.104,21.104,73.08,PAO,-1.703,0.361275,0.00474112,0.993057 kka2_1:8_G43V,kka2_1:8_43,Kka2,kka2_1:8,P00552,0.99306,NO,43,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.587,-3.838,2.251,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.100394,0.0071925,0.99306 kka2_1:8_G43V,kka2_1:8_43,Kka2,kka2_1:8,P00552,0.99306,NO,43,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.587,-3.838,2.251,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.100394,0.0071925,0.99306 PSD95pdz3_Q384C,PSD95pdz3_384,PSD95pdz3,PSD95pdz3,P31016,0.99306,NO,384,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-1.699,-4.769,3.07,5.49339,,,,,23.54,,,,OPP,-1.41333,0.0758425,0.000216736,0.99306 beta-lactamase_625_Q203V,beta-lactamase_625_203,TEM-1,beta-lactamase_625,P62593,0.993063,NO,203,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.168,-3.605,1.437,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.213352,0.00631514,0.993063 beta-lactamase_156_G194D,beta-lactamase_156_194,TEM-1,beta-lactamase_156,P62593,0.993067,NO,194,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.396,-2.314,0.918,,0.276,S,b,0.29,0.36,1.346,,67.83,POA,-1.832,0.111618,0.00392163,0.993067 beta-lactamase_L282I,beta-lactamase_282,TEM-1,beta-lactamase,P62593,0.993069,NO,282,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.586,-1.942,0.356,5.16743,0.007,H,A,1.07,0.34,31.31,31.31,63.99,PHH,-1.82367,0.221079,0.0449821,0.993069 beta-lactamase_625_M153R,beta-lactamase_625_153,TEM-1,beta-lactamase_625,P62593,0.99307,NO,153,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-3.193,-4.075,0.882,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.213352,0.00509109,0.99307 beta-lactamase_2500_R118L,beta-lactamase_2500_118,TEM-1,beta-lactamase_2500,P62593,0.993071,NO,118,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.413,-2.872,0.459,,0.457,H,A,1.2,1.39,2.144,,77.62,HBA,-1.785,0.361275,0.00538794,0.993071 beta-lactamase_156_L89G,beta-lactamase_156_89,TEM-1,beta-lactamase_156,P62593,0.993072,NO,89,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.096,-3.653,2.557,,0.168,T,A,0.55,0.63,2.633,,64.34,PHO,-1.75767,0.111618,0.00207068,0.993072 beta-lactamase_625_D207H,beta-lactamase_625_207,TEM-1,beta-lactamase_625,P62593,0.993075,NO,207,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.064,-3.07,1.006,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.213352,0.00592942,0.993075 beta-lactamase_156_K213R,beta-lactamase_156_213,TEM-1,beta-lactamase_156,P62593,0.99308,NO,213,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.81,-1.968,0.158,,0.67,,A,2.34,0.29,3.924,,67.83,ABH,-1.57767,0.111618,0.00610411,0.99308 beta-lactamase_156_G39I,beta-lactamase_156_39,TEM-1,beta-lactamase_156,P62593,0.993081,NO,39,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.864,-4.195,2.331,,0.701,T,L,0.29,0.47,1.454,,77.62,HOH,-1.53633,0.111618,0.00487611,0.993081 beta-lactamase_L73V,beta-lactamase_73,TEM-1,beta-lactamase,P62593,0.993087,NO,73,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.507,-2.286,0.779,5.84139,,H,A,1.75,-0.64,2.09,,67.83,HHH,-1.487,0.221079,0.00488983,0.993087 beta-lactamase_39_L49S,beta-lactamase_39_49,TEM-1,beta-lactamase_39,P62593,0.993088,NO,49,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.897,-2.417,0.52,,0.131,T,A,0.55,0.04,13.838,13.838,64.69,AHP,-1.99233,0.0495842,0.00401477,0.993088 beta-lactamase_156_A84E,beta-lactamase_156_84,TEM-1,beta-lactamase_156,P62593,0.993091,NO,84,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.651,-2.632,0.981,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.111618,0.00503822,0.993091 beta-lactamase_39_H156L,beta-lactamase_39_156,TEM-1,beta-lactamase_39,P62593,0.993092,NO,156,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-3.156,-3.026,-0.13,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.0495842,0.00468596,0.993092 beta-lactamase_39_T269R,beta-lactamase_39_269,TEM-1,beta-lactamase_39,P62593,0.993094,NO,269,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.156,,,,0.646,H,A,0.53,0.4,3.889,,77.62,HPH,-1.96733,0.0495842,0.00950944,0.993094 beta-lactamase_625_F149Q,beta-lactamase_625_149,TEM-1,beta-lactamase_625,P62593,0.993095,NO,149,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.299,-4.204,2.905,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.213352,0.00418462,0.993095 beta-lactamase_39_G114C,beta-lactamase_39_114,TEM-1,beta-lactamase_39,P62593,0.993096,NO,114,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.094,-5.014,3.92,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.0495842,0.00224919,0.993096 gb1_K230M,gb1_230,gb1,gb1,P06654,0.993096,NO,230,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.701,-4.291,2.59,,,,,,,0.166,,11.83,HBH,-1.52867,0.177985,0.00331703,0.993096 beta-lactamase_156_T269C,beta-lactamase_156_269,TEM-1,beta-lactamase_156,P62593,0.993097,NO,269,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.111618,0.00950944,0.993097 beta-lactamase_2500_M153I,beta-lactamase_2500_153,TEM-1,beta-lactamase_2500,P62593,0.993102,NO,153,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-3.193,-1.739,-1.454,,0.14,T,A,0.55,-0.11,3.409,,77.62,PHO,-2.25767,0.361275,0.00509109,0.993102 beta-lactamase_39_T116A,beta-lactamase_39_116,TEM-1,beta-lactamase_39,P62593,0.993103,NO,116,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.28,-2.469,1.189,,0.115,E,B,0.22,-0.12,1.133,,67.48,HPH,-1.39967,0.0495842,0.00336175,0.993103 beta-lactamase_39_E279P,beta-lactamase_39_279,TEM-1,beta-lactamase_39,P62593,0.993104,NO,279,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.0495842,0.0192826,0.993104 WW_domain_A175S,WW_domain_175,Yap65,WW_domain,P46937,0.993108,NO,175,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.631,-3.05,1.419,6.69537,,,,,,6.257,,83.93,OHO,-1.30033,0.153962,0.00326874,0.993108 beta-lactamase_625_Q267A,beta-lactamase_625_267,TEM-1,beta-lactamase_625,P62593,0.993109,NO,267,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.213352,0.0102128,0.993109 beta-lactamase_2500_H156K,beta-lactamase_2500_156,TEM-1,beta-lactamase_2500,P62593,0.99311,NO,156,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-3.156,-2.967,-0.189,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.361275,0.00468596,0.99311 beta-lactamase_156_L55E,beta-lactamase_156_55,TEM-1,beta-lactamase_156,P62593,0.993115,NO,55,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.86,-3.84,1.98,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.111618,0.00403741,0.993115 beta-lactamase_156_E175W,beta-lactamase_156_175,TEM-1,beta-lactamase_156,P62593,0.993121,NO,175,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.336,-5.537,3.201,,0.551,,A,1.04,1.05,2.334,,77.62,AAB,-1.31233,0.111618,0.00482205,0.993121 beta-lactamase_156_S57G,beta-lactamase_156_57,TEM-1,beta-lactamase_156,P62593,0.993124,NO,57,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.918,-2.176,0.258,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.111618,0.00492804,0.993124 beta-lactamase_625_E279S,beta-lactamase_625_279,TEM-1,beta-lactamase_625,P62593,0.993125,NO,279,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.213352,0.0192826,0.993125 beta-lactamase_39_P224H,beta-lactamase_39_224,TEM-1,beta-lactamase_39,P62593,0.993126,NO,224,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.893,-4.649,3.756,,0.383,,B,0.52,-0.3,3.169,,74.48,HOH,-1.26433,0.0495842,0.00189564,0.993126 beta-lactamase_625_L47V,beta-lactamase_625_47,TEM-1,beta-lactamase_625,P62593,0.993127,NO,47,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.876,-2.564,0.688,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.213352,0.00439844,0.993127 beta-lactamase_625_H156L,beta-lactamase_625_156,TEM-1,beta-lactamase_625,P62593,0.993129,NO,156,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-3.156,-3.026,-0.13,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.213352,0.00468596,0.993129 beta-lactamase_39_G141V,beta-lactamase_39_141,TEM-1,beta-lactamase_39,P62593,0.993131,NO,141,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.828,-3.79,2.962,,0.575,T,l,0.29,-0.28,0.722,,64.69,HOO,-1.08933,0.0495842,0.0012419,0.993131 beta-lactamase_625_S57D,beta-lactamase_625_57,TEM-1,beta-lactamase_625,P62593,0.993132,NO,57,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.918,-3.634,1.716,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.213352,0.00492804,0.993132 beta-lactamase_625_P105A,beta-lactamase_625_105,TEM-1,beta-lactamase_625,P62593,0.993138,NO,105,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.813,-3.041,2.228,,0.226,T,A,0.52,0.8,1.154,,63.29,POH,-1.01533,0.213352,0.0011981,0.993138 beta-lactamase_156_G141C,beta-lactamase_156_141,TEM-1,beta-lactamase_156,P62593,0.993141,NO,141,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.828,-5.167,4.339,,0.575,T,l,0.29,-0.28,0.198,,64.69,HOO,-1.08933,0.111618,0.0012419,0.993141 beta-lactamase_2500_A182T,beta-lactamase_2500_182,TEM-1,beta-lactamase_2500,P62593,0.993142,NO,182,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.777,-2.685,0.908,,0.136,H,A,0.46,-0.66,2.032,,93.01,OHH,-1.27367,0.361275,0.00559099,0.993142 beta-lactamase_39_L28R,beta-lactamase_39_28,TEM-1,beta-lactamase_39,P62593,0.993143,NO,28,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.579,-2.903,1.324,,0.277,H,A,0.55,-0.16,3.262,,93.01,PHH,-2.11333,0.0495842,0.00359321,0.993143 beta-lactamase_0_S57F,beta-lactamase_0_57,TEM-1,beta-lactamase_0,P62593,0.993144,NO,57,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.918,-4.274,2.356,,0.352,E,B,0.27,-0.18,1.454,,72.73,APH,-2.29167,0.0500837,0.00492804,0.993144 beta-lactamase_156_S233T,beta-lactamase_156_233,TEM-1,beta-lactamase_156,P62593,0.993148,NO,233,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.886,-1.229,-0.657,,0.016,E,B,0.27,-1.01,4.111,,77.62,BPO,-1.17267,0.111618,0.00311415,0.993148 beta-lactamase_39_S283R,beta-lactamase_39_283,TEM-1,beta-lactamase_39,P62593,0.993149,NO,283,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.0495842,0.0429138,0.993149 beta-lactamase_156_M115T,beta-lactamase_156_115,TEM-1,beta-lactamase_156,P62593,0.99315,NO,115,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.389,-3.522,2.133,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.111618,0.0034337,0.99315 beta-lactamase_156_T158A,beta-lactamase_156_158,TEM-1,beta-lactamase_156,P62593,0.993151,NO,158,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.116,-2.879,1.763,,0.036,,B,0.22,-0.85,3.771,,69.58,HPB,-1.269,0.111618,0.00341825,0.993151 beta-lactamase_39_A247M,beta-lactamase_39_247,TEM-1,beta-lactamase_39,P62593,0.993157,NO,247,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.0495842,0.00611275,0.993157 beta-lactamase_156_P172G,beta-lactamase_156_172,TEM-1,beta-lactamase_156,P62593,0.993159,NO,172,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.998,-3.35,2.352,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.111618,0.00312594,0.993159 beta-lactamase_39_R176F,beta-lactamase_39_176,TEM-1,beta-lactamase_39,P62593,0.993162,NO,176,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-0.863,-4.292,3.429,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.0495842,0.00105554,0.993162 beta-lactamase_156_Q97M,beta-lactamase_156_97,TEM-1,beta-lactamase_156,P62593,0.993167,NO,97,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.072,-3.413,1.341,,0.823,G,A,0.64,2.42,4.457,,77.62,PPP,-2.43833,0.111618,0.0045116,0.993167 beta-lactamase_156_T179S,beta-lactamase_156_179,TEM-1,beta-lactamase_156,P62593,0.993168,NO,179,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.085,-2.228,1.143,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.111618,0.00226045,0.993168 beta-lactamase_625_W163I,beta-lactamase_625_163,TEM-1,beta-lactamase_625,P62593,0.993178,NO,163,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-1.843,-3.136,1.293,,0.467,,B,0.47,-0.5,5.019,,63.99,BHA,-1.269,0.213352,0.00418955,0.993178 kka2_1:8_R202F,kka2_1:8_202,Kka2,kka2_1:8,P00552,0.993178,NO,202,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.761,-4.435,2.674,,0.607,E,B,1.2,0.48,1.409,,52.27,OBH,-1.41067,0.100394,0.00696498,0.993178 kka2_1:8_R202F,kka2_1:8_202,Kka2,kka2_1:8,P00552,0.993178,NO,202,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.761,-4.435,2.674,,0.607,E,B,1.2,0.48,1.409,,52.27,OBH,-1.41067,0.100394,0.00696498,0.993178 beta-lactamase_156_G142S,beta-lactamase_156_142,TEM-1,beta-lactamase_156,P62593,0.99318,NO,142,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.707,-2.438,1.731,,0.034,,p,0.29,-0.64,0.325,,64.69,OOO,-0.834,0.111618,0.00060149,0.99318 beta-lactamase_625_P165C,beta-lactamase_625_165,TEM-1,beta-lactamase_625,P62593,0.993182,NO,165,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.373,-4.892,3.519,,0.203,T,A,0.52,-0.31,0.414,,73.78,AOA,-1.359,0.213352,0.00549538,0.993182 beta-lactamase_39_H110M,beta-lactamase_39_110,TEM-1,beta-lactamase_39,P62593,0.993184,NO,110,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-1.706,-3.324,1.618,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.0495842,0.00441499,0.993184 beta-lactamase_39_K213N,beta-lactamase_39_213,TEM-1,beta-lactamase_39,P62593,0.993185,NO,213,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.81,-3.623,1.813,,0.67,,A,2.34,0.29,2.648,,67.83,ABH,-1.57767,0.0495842,0.00610411,0.993185 beta-lactamase_K190Y,beta-lactamase_190,TEM-1,beta-lactamase,P62593,0.993187,NO,190,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.994,-4.283,2.289,5.49163,0.371,H,A,1.82,0.16,29.753,29.753,77.62,BBH,-1.64167,0.221079,0.00574527,0.993187 beta-lactamase_T147T,beta-lactamase_147,TEM-1,beta-lactamase,P62593,0.993198,NO,147,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.149,-1.149,,5.37474,0.281,H,A,0.8,-0.68,2.838,,64.34,HPH,-1.456,0.221079,0.00226017,0.993198 beta-lactamase_0_A200L,beta-lactamase_0_200,TEM-1,beta-lactamase_0,P62593,0.993202,NO,200,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.878,-3.527,1.649,,0.757,H,A,0.46,-0.19,16.368,16.368,77.62,HHP,-2.001,0.0500837,0.0060056,0.993202 beta-lactamase_2500_S241A,beta-lactamase_2500_241,TEM-1,beta-lactamase_2500,P62593,0.99321,NO,241,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.361275,0.00452736,0.99321 beta-lactamase_625_A170D,beta-lactamase_625_170,TEM-1,beta-lactamase_625,P62593,0.99321,NO,170,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.237,-3.712,2.475,,0.126,,L,0.46,-0.35,3.626,,64.69,AHH,-1.63267,0.213352,0.00431903,0.99321 beta-lactamase_39_L100A,beta-lactamase_39_100,TEM-1,beta-lactamase_39,P62593,0.993218,NO,100,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.218,-3.158,1.94,,0.343,,B,0.55,0.13,8.311,,63.29,AHH,-1.23467,0.0495842,0.00413885,0.993218 beta-lactamase_39_L146A,beta-lactamase_39_146,TEM-1,beta-lactamase_39,P62593,0.99322,NO,146,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.462,-3.204,1.742,,0.007,H,A,0.55,-0.56,1.953,,64.69,AHP,-1.656,0.0495842,0.00474542,0.99322 beta-lactamase_156_T116Y,beta-lactamase_156_116,TEM-1,beta-lactamase_156,P62593,0.993222,NO,116,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.28,-4.295,3.015,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.111618,0.00336175,0.993222 beta-lactamase_39_P105I,beta-lactamase_39_105,TEM-1,beta-lactamase_39,P62593,0.993225,NO,105,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.813,-4.008,3.195,,0.226,T,A,0.52,0.8,1.222,,63.29,POH,-1.01533,0.0495842,0.0011981,0.993225 beta-lactamase_A132A,beta-lactamase_132,TEM-1,beta-lactamase,P62593,0.993231,NO,132,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.9,-0.9,,4.58504,,H,A,2.34,-0.93,2.217,,64.69,PHH,-1.138,0.221079,0.000962524,0.993231 beta-lactamase_625_S201R,beta-lactamase_625_201,TEM-1,beta-lactamase_625,P62593,0.993236,NO,201,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.183,-3.779,2.596,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.213352,0.00198815,0.993236 beta-lactamase_625_A182W,beta-lactamase_625_182,TEM-1,beta-lactamase_625,P62593,0.993237,NO,182,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.777,-5.53,3.753,,0.136,H,A,0.46,-0.66,16.784,16.784,93.01,OHH,-1.27367,0.213352,0.00559099,0.993237 beta-lactamase_156_E166Q,beta-lactamase_156_166,TEM-1,beta-lactamase_156,P62593,0.99324,NO,166,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.756,-3.022,1.266,,0.508,G,A,1.04,1.05,2.393,,73.08,OAH,-1.42233,0.111618,0.00512989,0.99324 beta-lactamase_156_S96E,beta-lactamase_156_96,TEM-1,beta-lactamase_156,P62593,0.993244,NO,96,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.27,-2.567,0.297,,0.368,,b,0.27,0.39,2.838,,73.78,HPP,-2.019,0.111618,0.00551835,0.993244 beta-lactamase_625_P217Y,beta-lactamase_625_217,TEM-1,beta-lactamase_625,P62593,0.993247,NO,217,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-2.062,-4.376,2.314,,0.496,I,A,0.52,-0.33,1.087,,74.48,OOH,-1.64333,0.213352,0.00463211,0.993247 beta-lactamase_39_E210H,beta-lactamase_39_210,TEM-1,beta-lactamase_39,P62593,0.993251,NO,210,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.319,-4.778,2.459,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.0495842,0.00663582,0.993251 beta-lactamase_156_A278Y,beta-lactamase_156_278,TEM-1,beta-lactamase_156,P62593,0.993252,NO,278,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.111618,0.0310297,0.993252 beta-lactamase_156_T269P,beta-lactamase_156_269,TEM-1,beta-lactamase_156,P62593,0.993252,NO,269,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.111618,0.00950944,0.993252 beta-lactamase_625_N173L,beta-lactamase_625_173,TEM-1,beta-lactamase_625,P62593,0.993252,NO,173,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-2.663,-3.749,1.086,,1.044,T,l,0.61,1.25,1.426,,77.62,OPA,-1.46633,0.213352,0.0033769,0.993252 beta-lactamase_156_L199W,beta-lactamase_156_199,TEM-1,beta-lactamase_156,P62593,0.993253,NO,199,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-2.942,-5.582,2.64,,0.832,H,A,0.55,0.42,1.552,,77.62,PHH,-2.32933,0.111618,0.0048649,0.993253 beta-lactamase_39_W163E,beta-lactamase_39_163,TEM-1,beta-lactamase_39,P62593,0.993259,NO,163,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-1.843,-3.693,1.85,,0.467,,B,0.47,-0.5,15.095,15.095,63.99,BHA,-1.269,0.0495842,0.00418955,0.993259 beta-lactamase_625_S51R,beta-lactamase_625_51,TEM-1,beta-lactamase_625,P62593,0.993261,NO,51,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.526,-2.956,1.43,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.213352,0.00504821,0.993261 beta-lactamase_625_A222G,beta-lactamase_625_222,TEM-1,beta-lactamase_625,P62593,0.993263,NO,222,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.103,-1.732,-0.371,,0.233,H,A,0.46,-0.25,1.448,,77.62,PHH,-1.63733,0.213352,0.00466094,0.993263 beta-lactamase_D113A,beta-lactamase_113,TEM-1,beta-lactamase,P62593,0.993269,NO,113,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.829,-2.412,0.583,6.04499,0.665,T,A,0.23,0.91,21.104,21.104,73.08,PAO,-1.703,0.221079,0.00474112,0.993269 beta-lactamase_N173T,beta-lactamase_173,TEM-1,beta-lactamase,P62593,0.993269,NO,173,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-2.663,-3.589,0.926,7.02497,1.044,T,l,0.09,1.25,1.88,,77.62,OPA,-1.46633,0.221079,0.0033769,0.993269 beta-lactamase_156_N168H,beta-lactamase_156_168,TEM-1,beta-lactamase_156,P62593,0.993273,NO,168,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-1.029,-4.17,3.141,,0.113,G,A,0.61,-0.4,1.014,,44.41,HPA,-1.13233,0.111618,0.00288667,0.993273 beta-lactamase_625_A77R,beta-lactamase_625_77,TEM-1,beta-lactamase_625,P62593,0.993274,NO,77,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.234,-3.891,2.657,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.213352,0.00282362,0.993274 beta-lactamase_625_I206K,beta-lactamase_625_206,TEM-1,beta-lactamase_625,P62593,0.993277,NO,206,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-2.429,-3.632,1.203,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.213352,0.00528934,0.993277 beta-lactamase_39_T116F,beta-lactamase_39_116,TEM-1,beta-lactamase_39,P62593,0.993285,NO,116,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.28,-4.243,2.963,,0.115,E,B,0.22,-0.12,1.133,,67.48,HPH,-1.39967,0.0495842,0.00336175,0.993285 beta-lactamase_39_G234C,beta-lactamase_39_234,TEM-1,beta-lactamase_39,P62593,0.993289,NO,234,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.62,-5.087,4.467,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.0495842,0.000889577,0.993289 beta-lactamase_156_T139F,beta-lactamase_156_139,TEM-1,beta-lactamase_156,P62593,0.993291,NO,139,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.901,-4.292,2.391,,0.216,H,A,0.22,0.39,16.34,16.34,77.62,PPH,-2.04667,0.111618,0.00441837,0.993291 beta-lactamase_625_L191F,beta-lactamase_625_191,TEM-1,beta-lactamase_625,P62593,0.993293,NO,191,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.087,-2.754,1.667,,,H,A,0.55,0.09,1.908,,63.29,BHH,-1.445,0.213352,0.00263549,0.993293 beta-lactamase_156_E145I,beta-lactamase_156_145,TEM-1,beta-lactamase_156,P62593,0.993294,NO,145,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.357,-4.11,1.753,,0.545,H,A,1.04,0.79,3.661,,77.62,BAH,-2.069,0.111618,0.00553285,0.993294 Pab1_D151A,Pab1_151,Pab1,Pab1,P04147,0.993296,NO,151,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.399,-3.138,0.739,,,,,,,,,,OAH,-1.51767,0.175299,0.00228155,0.993296 beta-lactamase_39_T264Q,beta-lactamase_39_264,TEM-1,beta-lactamase_39,P62593,0.993298,NO,264,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.0495842,0.0119399,0.993298 beta-lactamase_625_Q267E,beta-lactamase_625_267,TEM-1,beta-lactamase_625,P62593,0.993304,NO,267,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.213352,0.0102128,0.993304 beta-lactamase_156_G281S,beta-lactamase_156_281,TEM-1,beta-lactamase_156,P62593,0.993306,NO,281,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-2.247,-3.28,1.033,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.111618,0.0406482,0.993306 beta-lactamase_156_G39F,beta-lactamase_156_39,TEM-1,beta-lactamase_156,P62593,0.993306,NO,39,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.864,-4.451,2.587,,0.701,T,L,0.29,0.47,1.454,,77.62,HOH,-1.53633,0.111618,0.00487611,0.993306 beta-lactamase_2500_S80T,beta-lactamase_2500_80,TEM-1,beta-lactamase_2500,P62593,0.993308,NO,80,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.029,-2.845,0.816,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.361275,0.00565569,0.993308 beta-lactamase_39_I206L,beta-lactamase_39_206,TEM-1,beta-lactamase_39,P62593,0.993308,NO,206,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-2.429,-2.261,-0.168,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.0495842,0.00528934,0.993308 beta-lactamase_156_C121A,beta-lactamase_156_121,TEM-1,beta-lactamase_156,P62593,0.99331,NO,121,C,A,CA,Special,Hydrophobic,5.07,6,0.93,195,121,89,-32,108.5,88.6,-19.9,-0.953,-2.902,1.949,,,H,A,0.46,-0.81,1.136,,63.29,HOP,-1.46767,0.111618,0.000744322,0.99331 beta-lactamase_625_P250E,beta-lactamase_625_250,TEM-1,beta-lactamase_625,P62593,0.993314,NO,250,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.213352,0.00550899,0.993314 kka2_1:8_D183S,kka2_1:8_183,Kka2,kka2_1:8,P00552,0.993317,NO,183,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.204,-3.317,2.113,,0.518,.,b,0.75,0.25,0.347,,52.27,AAH,-1.40533,0.100394,0.00426304,0.993317 kka2_1:8_D183S,kka2_1:8_183,Kka2,kka2_1:8,P00552,0.993317,NO,183,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.204,-3.317,2.113,,0.518,.,b,0.75,0.25,0.347,,52.27,AAH,-1.40533,0.100394,0.00426304,0.993317 beta-lactamase_156_Y103H,beta-lactamase_156_103,TEM-1,beta-lactamase_156,P62593,0.993319,NO,103,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-1.33,-2.243,0.913,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.111618,0.00443048,0.993319 beta-lactamase_625_M180A,beta-lactamase_625_180,TEM-1,beta-lactamase_625,P62593,0.993323,NO,180,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-2.795,-2.974,0.179,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.213352,0.00552048,0.993323 beta-lactamase_156_F149A,beta-lactamase_156_149,TEM-1,beta-lactamase_156,P62593,0.99333,NO,149,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.299,-3.341,2.042,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.111618,0.00418462,0.99333 beta-lactamase_156_H287I,beta-lactamase_156_287,TEM-1,beta-lactamase_156,P62593,0.993332,NO,287,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,,,,,,,,,,,,,BBH,-1.111,0.111618,,0.993332 beta-lactamase_625_L89P,beta-lactamase_625_89,TEM-1,beta-lactamase_625,P62593,0.993332,NO,89,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.096,-2.221,1.125,,0.168,T,A,0.55,0.63,1.599,,64.34,PHO,-1.75767,0.213352,0.00207068,0.993332 beta-lactamase_0_K109V,beta-lactamase_0_109,TEM-1,beta-lactamase_0,P62593,0.993333,NO,109,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.734,-3.727,1.993,,0.787,G,A,2.34,2.21,15.473,15.473,72.73,ABB,-1.63333,0.0500837,0.00462493,0.993333 beta-lactamase_39_T158A,beta-lactamase_39_158,TEM-1,beta-lactamase_39,P62593,0.993337,NO,158,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.116,-2.879,1.763,,0.036,,B,0.22,-0.85,2.755,,69.58,HPB,-1.269,0.0495842,0.00341825,0.993337 beta-lactamase_39_I45H,beta-lactamase_39_45,TEM-1,beta-lactamase_39,P62593,0.993338,NO,45,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-2.421,-3.408,0.987,,,E,B,0.48,-0.3,2.256,,77.62,HHA,-2.30267,0.0495842,0.00452842,0.993338 kka2_1:4_T85I,kka2_1:4_85,Kka2,kka2_1:4,P00552,0.993338,NO,85,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.165,-2.979,0.814,,0.576,E,B,0.22,1.39,1.853,,71.59,HPA,-2.10133,0.168804,0.00634493,0.993338 beta-lactamase_39_Q37G,beta-lactamase_39_37,TEM-1,beta-lactamase_39,P62593,0.993339,NO,37,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.134,-3.507,1.373,,0.613,H,A,0.64,1.98,22.282,22.282,73.08,APH,-2.06967,0.0495842,0.00425833,0.993339 Pab1_E175N,Pab1_175,Pab1,Pab1,P04147,0.993348,NO,175,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.055,-2.294,0.239,,,,,,,,,,AAA,-1.82667,0.175299,0.00203137,0.993348 beta-lactamase_625_I140Q,beta-lactamase_625_140,TEM-1,beta-lactamase_625,P62593,0.99335,NO,140,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.733,-4.321,2.588,,0.128,H,A,0.48,0.41,1.628,,73.08,PHO,-1.48733,0.213352,0.00597777,0.99335 beta-lactamase_39_P255D,beta-lactamase_39_255,TEM-1,beta-lactamase_39,P62593,0.993351,NO,255,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.0495842,0.00499612,0.993351 beta-lactamase_2500_T138Q,beta-lactamase_2500_138,TEM-1,beta-lactamase_2500,P62593,0.993352,NO,138,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.506,-3.82,1.314,,0.662,H,A,0.22,-0.03,30.445,30.445,73.78,HPP,-1.81233,0.361275,0.00487868,0.993352 beta-lactamase_625_M153L,beta-lactamase_625_153,TEM-1,beta-lactamase_625,P62593,0.993356,NO,153,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-3.193,-1.8,-1.393,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.213352,0.00509109,0.993356 PSD95pdz3_A390R,PSD95pdz3_390,PSD95pdz3,PSD95pdz3,P31016,0.993358,NO,390,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.307,-3.39,2.083,5.03823,,,,,12.46,,,,HHP,-1.54467,0.0758425,0.00104603,0.993358 beta-lactamase_625_P172T,beta-lactamase_625_172,TEM-1,beta-lactamase_625,P62593,0.993359,NO,172,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.998,-3.409,2.411,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.213352,0.00312594,0.993359 beta-lactamase_2500_A278R,beta-lactamase_2500_278,TEM-1,beta-lactamase_2500,P62593,0.993365,NO,278,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.361275,0.0310297,0.993365 beta-lactamase_2500_E166W,beta-lactamase_2500_166,TEM-1,beta-lactamase_2500,P62593,0.993365,NO,166,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.756,-5.495,3.739,,0.508,G,A,1.04,1.05,2.124,,73.08,OAH,-1.42233,0.361275,0.00512989,0.993365 beta-lactamase_625_M153F,beta-lactamase_625_153,TEM-1,beta-lactamase_625,P62593,0.993367,NO,153,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-3.193,-3.944,0.751,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.213352,0.00509109,0.993367 beta-lactamase_156_L197G,beta-lactamase_156_197,TEM-1,beta-lactamase_156,P62593,0.993371,NO,197,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.853,-3.681,2.828,,0.007,S,B,0.55,0.33,1.58,,60.14,HHP,-1.833,0.111618,0.00144602,0.993371 beta-lactamase_625_L38M,beta-lactamase_625_38,TEM-1,beta-lactamase_625,P62593,0.993371,NO,38,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.343,-4.186,2.843,,0.088,H,A,0.55,0.2,1.986,,64.34,PHO,-1.78033,0.213352,0.00373244,0.993371 Pab1_A185C,Pab1_185,Pab1,Pab1,P04147,0.993373,NO,185,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.702,-4.685,2.983,,,,,,,1.756,,63.26,AHH,-1.66167,0.175299,0.00144499,0.993373 beta-lactamase_156_P165Q,beta-lactamase_156_165,TEM-1,beta-lactamase_156,P62593,0.993375,NO,165,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.373,-3.97,2.597,,0.203,T,A,0.52,-0.31,3.907,,73.78,AOA,-1.359,0.111618,0.00549538,0.993375 beta-lactamase_K252C,beta-lactamase_252,TEM-1,beta-lactamase,P62593,0.993375,NO,252,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.94,-5.259,3.319,5.56823,0.766,,B,1.82,1.16,21.796,21.796,67.83,OBO,-2.03333,0.221079,0.00575769,0.993375 beta-lactamase_156_E279W,beta-lactamase_156_279,TEM-1,beta-lactamase_156,P62593,0.993382,NO,279,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.111618,0.0192826,0.993382 beta-lactamase_2500_S80F,beta-lactamase_2500_80,TEM-1,beta-lactamase_2500,P62593,0.993385,NO,80,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.029,-4.287,2.258,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.361275,0.00565569,0.993385 beta-lactamase_39_A278M,beta-lactamase_39_278,TEM-1,beta-lactamase_39,P62593,0.993391,NO,278,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.0495842,0.0310297,0.993391 beta-lactamase_S57Q,beta-lactamase_57,TEM-1,beta-lactamase,P62593,0.993395,NO,57,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.918,-3.995,2.077,5.64201,0.352,E,B,0.25,-0.18,1.971,,72.73,APH,-2.29167,0.221079,0.00492804,0.993395 beta-lactamase_625_P25S,beta-lactamase_625_25,TEM-1,beta-lactamase_625,P62593,0.993396,NO,25,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.526,-3.274,1.748,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.213352,0.00347571,0.993396 beta-lactamase_625_R162K,beta-lactamase_625_162,TEM-1,beta-lactamase_625,P62593,0.993396,NO,162,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.016,-2.948,1.932,,0.124,S,B,1.2,-0.37,1.445,,64.69,ABH,-1.25,0.213352,0.000561334,0.993396 beta-lactamase_39_E119Y,beta-lactamase_39_119,TEM-1,beta-lactamase_39,P62593,0.993397,NO,119,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.412,-4.336,2.924,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.0495842,0.00386966,0.993397 beta-lactamase_39_V117F,beta-lactamase_39_117,TEM-1,beta-lactamase_39,P62593,0.9934,NO,117,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.53,-3.756,2.226,,,H,A,0.44,-0.34,1.182,,65.03,PHB,-1.741,0.0495842,0.00467906,0.9934 beta-lactamase_156_Q86D,beta-lactamase_156_86,TEM-1,beta-lactamase_156,P62593,0.993416,NO,86,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.4,-2.27,-0.13,,0.696,S,A,0.64,2.38,27.704,27.704,77.62,OPA,-1.61067,0.111618,0.00450027,0.993416 beta-lactamase_2500_E87I,beta-lactamase_2500_87,TEM-1,beta-lactamase_2500,P62593,0.993416,NO,87,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.421,-3.687,2.266,,0.048,,B,1.04,0.92,17.923,17.923,64.69,PAP,-1.969,0.361275,0.00337888,0.993416 beta-lactamase_625_Q203G,beta-lactamase_625_203,TEM-1,beta-lactamase_625,P62593,0.993416,NO,203,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.168,-2.805,0.637,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.213352,0.00631514,0.993416 beta-lactamase_39_S57P,beta-lactamase_39_57,TEM-1,beta-lactamase_39,P62593,0.99342,NO,57,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.918,-3.952,2.034,,0.352,E,B,0.27,-0.18,2.3,,72.73,APH,-2.29167,0.0495842,0.00492804,0.99342 beta-lactamase_625_D99E,beta-lactamase_625_99,TEM-1,beta-lactamase_625,P62593,0.993421,NO,99,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.191,-2.122,0.931,,0.402,G,A,0.75,0.36,1.318,,64.69,PAH,-1.794,0.213352,0.00305446,0.993421 beta-lactamase_0_E62V,beta-lactamase_0_62,TEM-1,beta-lactamase_0,P62593,0.993422,NO,62,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.193,-3.636,2.443,,0.342,S,B,1.04,-0.3,5.784,,73.08,AAB,-1.417,0.0500837,0.00264802,0.993422 beta-lactamase_39_L89D,beta-lactamase_39_89,TEM-1,beta-lactamase_39,P62593,0.993424,NO,89,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.096,-3.996,2.9,,0.168,T,A,0.55,0.63,3.233,,64.34,PHO,-1.75767,0.0495842,0.00207068,0.993424 beta-lactamase_39_K286Y,beta-lactamase_39_286,TEM-1,beta-lactamase_39,P62593,0.993425,NO,286,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.0495842,,0.993425 beta-lactamase_156_K213Y,beta-lactamase_156_213,TEM-1,beta-lactamase_156,P62593,0.993427,NO,213,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.81,-4.305,2.495,,0.67,,A,2.34,0.29,3.924,,67.83,ABH,-1.57767,0.111618,0.00610411,0.993427 beta-lactamase_39_P217Q,beta-lactamase_39_217,TEM-1,beta-lactamase_39,P62593,0.993427,NO,217,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-2.062,-3.933,1.871,,0.496,I,A,0.52,-0.33,21.172,21.172,74.48,OOH,-1.64333,0.0495842,0.00463211,0.993427 beta-lactamase_2500_K144E,beta-lactamase_2500_144,TEM-1,beta-lactamase_2500,P62593,0.993429,NO,144,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-2.388,-2.372,-0.016,,0.863,H,A,2.34,1.27,0.515,,77.62,OBA,-1.904,0.361275,0.00481141,0.993429 beta-lactamase_39_L55E,beta-lactamase_39_55,TEM-1,beta-lactamase_39,P62593,0.993429,NO,55,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.86,-3.84,1.98,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.0495842,0.00403741,0.993429 beta-lactamase_625_K144N,beta-lactamase_625_144,TEM-1,beta-lactamase_625,P62593,0.99343,NO,144,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-2.388,-3.043,0.655,,0.863,H,A,2.34,1.27,2.313,,77.62,OBA,-1.904,0.213352,0.00481141,0.99343 beta-lactamase_0_S96A,beta-lactamase_0_96,TEM-1,beta-lactamase_0,P62593,0.993433,NO,96,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.27,-2.75,0.48,,0.368,,b,0.27,0.39,2.516,,73.78,HPP,-2.019,0.0500837,0.00551835,0.993433 beta-lactamase_625_A278I,beta-lactamase_625_278,TEM-1,beta-lactamase_625,P62593,0.993435,NO,278,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.348,-3.123,1.775,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.213352,0.0310297,0.993435 beta-lactamase_625_I93L,beta-lactamase_625_93,TEM-1,beta-lactamase_625,P62593,0.99344,NO,93,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.401,-2.05,0.649,,0.128,E,B,0.48,0.44,1.524,,67.83,BHB,-1.873,0.213352,0.00527066,0.99344 beta-lactamase_39_A278T,beta-lactamase_39_278,TEM-1,beta-lactamase_39,P62593,0.993441,NO,278,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.0495842,0.0310297,0.993441 beta-lactamase_156_Y44F,beta-lactamase_156_44,TEM-1,beta-lactamase_156,P62593,0.993443,NO,44,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-2.547,-2.714,0.167,,,E,B,0.21,-0.45,2.184,,73.78,OHH,-1.86267,0.111618,0.00426364,0.993443 kka2_1:8_M116F,kka2_1:8_116,Kka2,kka2_1:8,P00552,0.993446,NO,116,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-2.482,-3.107,0.625,,,H,A,1.59,-0.88,4.659,,71.59,HHH,-1.63867,0.100394,0.00745147,0.993446 kka2_1:8_M116F,kka2_1:8_116,Kka2,kka2_1:8,P00552,0.993446,NO,116,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-2.482,-3.107,0.625,,,H,A,1.59,-0.88,4.659,,71.59,HHH,-1.63867,0.100394,0.00745147,0.993446 kka2_1:8_Y218V,kka2_1:8_218,Kka2,kka2_1:8,P00552,0.993446,NO,218,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-1.438,-3.601,2.163,,0.122,H,A,1.25,-0.69,2.923,,56.06,BHP,-1.17533,0.100394,0.0126098,0.993446 kka2_1:8_Y218V,kka2_1:8_218,Kka2,kka2_1:8,P00552,0.993446,NO,218,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-1.438,-3.601,2.163,,0.122,H,A,1.25,-0.69,2.923,,56.06,BHP,-1.17533,0.100394,0.0126098,0.993446 beta-lactamase_2500_N98F,beta-lactamase_2500_98,TEM-1,beta-lactamase_2500,P62593,0.993448,NO,98,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-2.973,-3.271,0.298,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.361275,0.00505389,0.993448 beta-lactamase_156_Y95F,beta-lactamase_156_95,TEM-1,beta-lactamase_156,P62593,0.993449,NO,95,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-1.715,-2.096,0.381,,0.122,,b,0.21,-0.37,2.341,,77.62,BHP,-2.16167,0.111618,0.00479449,0.993449 beta-lactamase_39_D207N,beta-lactamase_39_207,TEM-1,beta-lactamase_39,P62593,0.993451,NO,207,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.064,-2.966,0.902,,0.409,H,A,0.75,0.12,14.511,14.511,77.62,HAH,-1.77033,0.0495842,0.00592942,0.993451 beta-lactamase_156_I206R,beta-lactamase_156_206,TEM-1,beta-lactamase_156,P62593,0.993453,NO,206,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-2.429,-3.125,0.696,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.111618,0.00528934,0.993453 beta-lactamase_156_V72T,beta-lactamase_156_72,TEM-1,beta-lactamase_156,P62593,0.993453,NO,72,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.658,-2.757,1.099,,,H,A,0.44,-1.03,1.92,,65.73,BHH,-1.32167,0.111618,0.00501194,0.993453 beta-lactamase_2500_T138I,beta-lactamase_2500_138,TEM-1,beta-lactamase_2500,P62593,0.993459,NO,138,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.506,-4.099,1.593,,0.662,H,A,0.22,-0.03,30.445,30.445,73.78,HPP,-1.81233,0.361275,0.00487868,0.993459 beta-lactamase_625_P172F,beta-lactamase_625_172,TEM-1,beta-lactamase_625,P62593,0.993461,NO,172,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.998,-4.371,3.373,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.213352,0.00312594,0.993461 Pab1_E174A,Pab1_174,Pab1,Pab1,P04147,0.993462,NO,174,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.422,-3.06,1.638,,0.578,S,A,,0.38,,,,HAA,-1.65133,0.175299,0.00077863,0.993462 beta-lactamase_I206S,beta-lactamase_206,TEM-1,beta-lactamase,P62593,0.993467,NO,206,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-2.429,-3.468,1.039,5.3727,0.173,H,A,1,-0.34,2.061,,77.62,HHA,-1.805,0.221079,0.00528934,0.993467 beta-lactamase_156_L167S,beta-lactamase_156_167,TEM-1,beta-lactamase_156,P62593,0.993468,NO,167,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.138,-2.747,1.609,,0.015,G,A,0.55,-0.63,0.4,,64.69,AHP,-1.30767,0.111618,0.00303566,0.993468 beta-lactamase_625_S283L,beta-lactamase_625_283,TEM-1,beta-lactamase_625,P62593,0.993471,NO,283,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.213352,0.0429138,0.993471 kka2_1:4_T51N,kka2_1:4_51,Kka2,kka2_1:4,P00552,0.993475,NO,51,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.199,-3.862,1.663,,0.05,E,B,0.82,-0.05,13.165,13.165,63.64,BPA,-1.76767,0.168804,0.00628861,0.993475 beta-lactamase_625_S283W,beta-lactamase_625_283,TEM-1,beta-lactamase_625,P62593,0.993477,NO,283,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.213352,0.0429138,0.993477 beta-lactamase_39_T112H,beta-lactamase_39_112,TEM-1,beta-lactamase_39,P62593,0.993488,NO,112,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.186,-4.734,2.548,,0.921,T,A,0.22,1.06,2.87,,73.78,HPA,-1.925,0.0495842,0.00531334,0.993488 beta-lactamase_156_E175D,beta-lactamase_156_175,TEM-1,beta-lactamase_156,P62593,0.993497,NO,175,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.336,-2.916,0.58,,0.551,,A,1.04,1.05,2.334,,77.62,AAB,-1.31233,0.111618,0.00482205,0.993497 beta-lactamase_625_T198F,beta-lactamase_625_198,TEM-1,beta-lactamase_625,P62593,0.993497,NO,198,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.168,-4.258,2.09,,0.489,,B,0.22,-0.13,0.37,,73.78,HPH,-1.98767,0.213352,0.004311,0.993497 beta-lactamase_156_D207G,beta-lactamase_156_207,TEM-1,beta-lactamase_156,P62593,0.993498,NO,207,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.064,-2.283,0.219,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.111618,0.00592942,0.993498 beta-lactamase_625_D252V,beta-lactamase_625_252,TEM-1,beta-lactamase_625,P62593,0.993499,NO,252,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.213352,0.00575769,0.993499 beta-lactamase_156_R159A,beta-lactamase_156_159,TEM-1,beta-lactamase_156,P62593,0.993501,NO,159,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-0.94,-3.127,2.187,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.111618,0.00108472,0.993501 beta-lactamase_156_A235M,beta-lactamase_156_235,TEM-1,beta-lactamase_156,P62593,0.993503,NO,235,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.266,-4.612,3.346,,0.32,E,B,0.46,-0.86,1.344,,50,OHO,-0.89,0.111618,0.00493474,0.993503 beta-lactamase_156_P65H,beta-lactamase_156_65,TEM-1,beta-lactamase_156,P62593,0.993503,NO,65,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.894,-4.735,3.841,,0.098,E,B,0.52,-0.62,0.623,,40.56,HOH,-1.03233,0.111618,0.00152776,0.993503 beta-lactamase_156_R63P,beta-lactamase_156_63,TEM-1,beta-lactamase_156,P62593,0.993503,NO,63,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-0.943,-3.929,2.986,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.111618,0.00126938,0.993503 beta-lactamase_625_I229V,beta-lactamase_625_229,TEM-1,beta-lactamase_625,P62593,0.993506,NO,229,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.267,-1.684,0.417,,0.083,E,B,0.48,-0.76,1.69,,50,HHH,-1.58767,0.213352,0.00477249,0.993506 beta-lactamase_625_D207R,beta-lactamase_625_207,TEM-1,beta-lactamase_625,P62593,0.993507,NO,207,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.064,-2.841,0.777,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.213352,0.00592942,0.993507 beta-lactamase_0_A211I,beta-lactamase_0_211,TEM-1,beta-lactamase_0,P62593,0.993511,NO,211,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.896,-4.033,2.137,,0.369,T,A,0.46,-0.69,8.527,8.527,77.62,AHA,-1.94633,0.0500837,0.00648183,0.993511 PSD95pdz3_T387Q,PSD95pdz3_387,PSD95pdz3,PSD95pdz3,P31016,0.993515,NO,387,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.391,-3.581,2.19,5.20757,,,,,18.8043,,,,HPH,-1.49533,0.0758425,0.000167911,0.993515 beta-lactamase_156_G114H,beta-lactamase_156_114,TEM-1,beta-lactamase_156,P62593,0.993519,NO,114,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.094,-4.665,3.571,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.111618,0.00224919,0.993519 beta-lactamase_156_K32H,beta-lactamase_156_32,TEM-1,beta-lactamase_156,P62593,0.993519,NO,32,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.984,-4.632,2.648,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.111618,0.00401283,0.993519 beta-lactamase_625_K32R,beta-lactamase_625_32,TEM-1,beta-lactamase_625,P62593,0.993523,NO,32,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.984,-2.38,0.396,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.213352,0.00401283,0.993523 beta-lactamase_156_P165M,beta-lactamase_156_165,TEM-1,beta-lactamase_156,P62593,0.993524,NO,165,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.373,-4.649,3.276,,0.203,T,A,0.52,-0.31,3.907,,73.78,AOA,-1.359,0.111618,0.00549538,0.993524 beta-lactamase_39_S283L,beta-lactamase_39_283,TEM-1,beta-lactamase_39,P62593,0.993525,NO,283,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.0495842,0.0429138,0.993525 beta-lactamase_T116T,beta-lactamase_116,TEM-1,beta-lactamase,P62593,0.993528,NO,116,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.28,-1.28,,4.78335,0.115,E,B,0.69,-0.12,0.343,,67.48,HPH,-1.39967,0.221079,0.00336175,0.993528 beta-lactamase_625_I229M,beta-lactamase_625_229,TEM-1,beta-lactamase_625,P62593,0.99353,NO,229,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.267,-4.125,2.858,,0.083,E,B,0.48,-0.76,1.69,,50,HHH,-1.58767,0.213352,0.00477249,0.99353 beta-lactamase_156_E145V,beta-lactamase_156_145,TEM-1,beta-lactamase_156,P62593,0.993535,NO,145,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.357,-3.665,1.308,,0.545,H,A,1.04,0.79,3.661,,77.62,BAH,-2.069,0.111618,0.00553285,0.993535 beta-lactamase_39_A247W,beta-lactamase_39_247,TEM-1,beta-lactamase_39,P62593,0.993536,NO,247,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.0495842,0.00611275,0.993536 beta-lactamase_625_V78T,beta-lactamase_625_78,TEM-1,beta-lactamase_625,P62593,0.993537,NO,78,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.459,-3.492,2.033,,,H,A,0.44,-0.47,2.045,,63.64,HHH,-1.17833,0.213352,0.00492501,0.993537 beta-lactamase_156_I54R,beta-lactamase_156_54,TEM-1,beta-lactamase_156,P62593,0.993539,NO,54,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-2.838,-2.365,-0.473,,0.669,E,B,0.48,-0.14,0.541,,73.78,BHH,-2.337,0.111618,0.00403589,0.993539 beta-lactamase_156_T198P,beta-lactamase_156_198,TEM-1,beta-lactamase_156,P62593,0.993541,NO,198,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.168,-2.894,0.726,,0.489,,B,0.22,-0.13,10.771,10.771,73.78,HPH,-1.98767,0.111618,0.004311,0.993541 Pab1_G163G,Pab1_163,Pab1,Pab1,P04147,0.993541,NO,163,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.809,-0.809,,,0.356,B,g,,0.55,,,,POB,-1.80667,0.175299,0.00030953,0.993541 beta-lactamase_39_S221E,beta-lactamase_39_221,TEM-1,beta-lactamase_39,P62593,0.993544,NO,221,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.754,-3.442,1.688,,0.624,H,A,0.27,-0.2,2.69,,74.48,BPH,-1.59967,0.0495842,0.0046094,0.993544 beta-lactamase_625_R91E,beta-lactamase_625_91,TEM-1,beta-lactamase_625,P62593,0.993544,NO,91,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.392,-2.211,0.819,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.213352,0.00380226,0.993544 beta-lactamase_2500_N50W,beta-lactamase_2500_50,TEM-1,beta-lactamase_2500,P62593,0.993547,NO,50,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-2.979,-5.454,2.475,,0.912,T,A,0.61,1.24,1.581,,77.62,HPP,-2.134,0.361275,0.0047211,0.993547 PSD95pdz3_I359L,PSD95pdz3_359,PSD95pdz3,PSD95pdz3,P31016,0.993548,NO,359,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.63,-2.14,0.51,5.35151,,,,,14.8012,,,,PHH,-1.58667,0.0758425,0.000580694,0.993548 kka2_1:1_Q4N,kka2_1:1_4,Kka2,kka2_1:1,P00552,0.993559,NO,4,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.361,-1.87,-0.491,,,,,,,5.615,,71.59,APA,-1.95533,0.520039,0.00239179,0.993559 beta-lactamase_156_K53Q,beta-lactamase_156_53,TEM-1,beta-lactamase_156,P62593,0.99356,NO,53,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-2.313,-2.642,0.329,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.111618,0.00383383,0.99356 beta-lactamase_156_E210H,beta-lactamase_156_210,TEM-1,beta-lactamase_156,P62593,0.993561,NO,210,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.319,-4.778,2.459,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.111618,0.00663582,0.993561 Pab1_A178F,Pab1_178,Pab1,Pab1,P04147,0.993561,NO,178,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.579,-3.989,2.41,,0.019,H,A,0.64,0.64,2.7,,81.63,OHH,-1.61067,0.175299,0.00160192,0.993561 beta-lactamase_39_L111W,beta-lactamase_39_111,TEM-1,beta-lactamase_39,P62593,0.993562,NO,111,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.76,-5.305,3.545,,0.328,T,A,0.55,0.93,4.334,,64.34,BHP,-1.884,0.0495842,0.00480671,0.993562 kka2_1:8_W69G,kka2_1:8_69,Kka2,kka2_1:8,P00552,0.993563,NO,69,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-0.859,-3.43,2.571,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.100394,0.0012874,0.993563 kka2_1:8_W69G,kka2_1:8_69,Kka2,kka2_1:8,P00552,0.993563,NO,69,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-0.859,-3.43,2.571,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.100394,0.0012874,0.993563 beta-lactamase_156_P217G,beta-lactamase_156_217,TEM-1,beta-lactamase_156,P62593,0.993566,NO,217,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-2.062,-2.748,0.686,,0.496,I,A,0.52,-0.33,2.303,,74.48,OOH,-1.64333,0.111618,0.00463211,0.993566 beta-lactamase_625_L199Q,beta-lactamase_625_199,TEM-1,beta-lactamase_625,P62593,0.993568,NO,199,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-2.942,-3.22,0.278,,0.832,H,A,0.55,0.42,1.552,,77.62,PHH,-2.32933,0.213352,0.0048649,0.993568 beta-lactamase_156_H24F,beta-lactamase_156_24,TEM-1,beta-lactamase_156,P62593,0.993571,NO,24,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-2.481,-4.152,1.671,,,,,,,2.708,,93.01,OBO,-2.0035,0.111618,0.00238894,0.993571 beta-lactamase_625_G52E,beta-lactamase_625_52,TEM-1,beta-lactamase_625,P62593,0.99358,NO,52,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.149,-3.424,2.275,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.213352,0.00340138,0.99358 beta-lactamase_156_P165F,beta-lactamase_156_165,TEM-1,beta-lactamase_156,P62593,0.993586,NO,165,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.373,-4.322,2.949,,0.203,T,A,0.52,-0.31,3.907,,73.78,AOA,-1.359,0.111618,0.00549538,0.993586 beta-lactamase_39_D207I,beta-lactamase_39_207,TEM-1,beta-lactamase_39,P62593,0.993593,NO,207,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.064,-4.165,2.101,,0.409,H,A,0.75,0.12,14.511,14.511,77.62,HAH,-1.77033,0.0495842,0.00592942,0.993593 beta-lactamase_39_N50G,beta-lactamase_39_50,TEM-1,beta-lactamase_39,P62593,0.993595,NO,50,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-2.979,-2.053,-0.926,,0.912,T,A,0.61,1.24,10.736,,77.62,HPP,-2.134,0.0495842,0.0047211,0.993595 beta-lactamase_625_Q97M,beta-lactamase_625_97,TEM-1,beta-lactamase_625,P62593,0.993596,NO,97,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.072,-3.413,1.341,,0.823,G,A,0.64,2.42,16.954,16.954,77.62,PPP,-2.43833,0.213352,0.0045116,0.993596 beta-lactamase_156_L38Q,beta-lactamase_156_38,TEM-1,beta-lactamase_156,P62593,0.993599,NO,38,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.343,-4.155,2.812,,0.088,H,A,0.55,0.2,13.556,13.556,64.34,PHO,-1.78033,0.111618,0.00373244,0.993599 gb1_D266Q,gb1_266,gb1,gb1,P06654,0.993599,NO,266,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.261,-3.574,2.313,,,,,,,0.638,,45.54,HAO,-1.59333,0.177985,0.00394694,0.993599 gb1_Q258L,gb1_258,gb1,gb1,P06654,0.993599,NO,258,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.095,-3.353,1.258,,,,,,,0.86,,37.28,BPH,-1.88333,0.177985,0.00437595,0.993599 beta-lactamase_625_S80D,beta-lactamase_625_80,TEM-1,beta-lactamase_625,P62593,0.993607,NO,80,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.029,-2.7,0.671,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.213352,0.00565569,0.993607 beta-lactamase_2500_P60G,beta-lactamase_2500_60,TEM-1,beta-lactamase_2500,P62593,0.993615,NO,60,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-2.469,-2.095,-0.374,,0.256,T,A,0.52,-0.56,1.581,,77.62,BOA,-1.97633,0.361275,0.00521318,0.993615 beta-lactamase_625_P165G,beta-lactamase_625_165,TEM-1,beta-lactamase_625,P62593,0.993615,NO,165,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.373,-3.429,2.056,,0.203,T,A,0.52,-0.31,0.414,,73.78,AOA,-1.359,0.213352,0.00549538,0.993615 Pab1_E195D,Pab1_195,Pab1,Pab1,P04147,0.993618,NO,195,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.2,-2.757,1.557,,,,,,,,,,PAH,-1.72467,0.175299,0.000620107,0.993618 beta-lactamase_39_A222L,beta-lactamase_39_222,TEM-1,beta-lactamase_39,P62593,0.993619,NO,222,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.103,-3.403,1.3,,0.233,H,A,0.46,-0.25,1.448,,77.62,PHH,-1.63733,0.0495842,0.00466094,0.993619 beta-lactamase_625_E61W,beta-lactamase_625_61,TEM-1,beta-lactamase_625,P62593,0.99362,NO,61,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.115,-5.544,3.429,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.213352,0.00440955,0.99362 beta-lactamase_2500_T139A,beta-lactamase_2500_139,TEM-1,beta-lactamase_2500,P62593,0.993621,NO,139,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.901,-2.031,0.13,,0.216,H,A,0.22,0.39,2.256,,77.62,PPH,-2.04667,0.361275,0.00441837,0.993621 beta-lactamase_625_G85Q,beta-lactamase_625_85,TEM-1,beta-lactamase_625,P62593,0.993621,NO,85,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.011,-3.928,2.917,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.213352,0.00252173,0.993621 beta-lactamase_156_K213G,beta-lactamase_156_213,TEM-1,beta-lactamase_156,P62593,0.993624,NO,213,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.81,-2.317,0.507,,0.67,,A,2.34,0.29,3.924,,67.83,ABH,-1.57767,0.111618,0.00610411,0.993624 beta-lactamase_156_K32G,beta-lactamase_156_32,TEM-1,beta-lactamase_156,P62593,0.993626,NO,32,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.984,-3.506,1.522,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.111618,0.00401283,0.993626 beta-lactamase_156_N168L,beta-lactamase_156_168,TEM-1,beta-lactamase_156,P62593,0.993626,NO,168,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-1.029,-3.516,2.487,,0.113,G,A,0.61,-0.4,1.014,,44.41,HPA,-1.13233,0.111618,0.00288667,0.993626 beta-lactamase_P12S,beta-lactamase_12,TEM-1,beta-lactamase,P62593,0.993626,NO,12,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-2.016,-2.028,0.012,,,,,,,2.88,,72.73,HOH,-2.05167,0.221079,0.00241653,0.993626 beta-lactamase_625_A282N,beta-lactamase_625_282,TEM-1,beta-lactamase_625,P62593,0.993628,NO,282,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.213352,0.0449821,0.993628 beta-lactamase_156_E35Q,beta-lactamase_156_35,TEM-1,beta-lactamase_156,P62593,0.993631,NO,35,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-0.869,-3.292,2.423,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.111618,0.00174441,0.993631 beta-lactamase_156_R81Y,beta-lactamase_156_81,TEM-1,beta-lactamase_156,P62593,0.993633,NO,81,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.466,-4.271,2.805,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.111618,0.00499763,0.993633 beta-lactamase_39_L199H,beta-lactamase_39_199,TEM-1,beta-lactamase_39,P62593,0.993635,NO,199,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-2.942,-4.8,1.858,,0.832,H,A,0.55,0.42,15.504,15.504,77.62,PHH,-2.32933,0.0495842,0.0048649,0.993635 beta-lactamase_39_A77T,beta-lactamase_39_77,TEM-1,beta-lactamase_39,P62593,0.993637,NO,77,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.234,-2.687,1.453,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.0495842,0.00282362,0.993637 beta-lactamase_625_T147G,beta-lactamase_625_147,TEM-1,beta-lactamase_625,P62593,0.99364,NO,147,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.149,-2.499,1.35,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.213352,0.00226017,0.99364 PSD95pdz3_G383T,PSD95pdz3_383,PSD95pdz3,PSD95pdz3,P31016,0.993642,NO,383,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.008,-3.328,2.32,5.17213,,,,,20.5325,,,,HOP,-1.338,0.0758425,0.000233044,0.993642 beta-lactamase_39_S96K,beta-lactamase_39_96,TEM-1,beta-lactamase_39,P62593,0.993643,NO,96,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.27,-2.895,0.625,,0.368,,b,0.27,0.39,2.516,,73.78,HPP,-2.019,0.0495842,0.00551835,0.993643 Pab1_N162T,Pab1_162,Pab1,Pab1,P04147,0.993643,NO,162,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-2.313,-2.448,0.135,,0.681,T,A,,1.12,,,,APO,-1.532,0.175299,0.0030719,0.993643 beta-lactamase_156_Q267K,beta-lactamase_156_267,TEM-1,beta-lactamase_156,P62593,0.993647,NO,267,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.111618,0.0102128,0.993647 kka2_1:4_L158M,kka2_1:4_158,Kka2,kka2_1:4,P00552,0.99365,NO,158,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.947,-4.254,2.307,,0.095,,B,1.59,0.77,7.588,,63.64,AHA,-1.25333,0.168804,0.00529068,0.99365 beta-lactamase_2500_A148N,beta-lactamase_2500_148,TEM-1,beta-lactamase_2500,P62593,0.993657,NO,148,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.757,-3.701,1.944,,0.379,H,A,0.46,-0.55,2.117,,72.73,PHH,-1.40167,0.361275,0.00547053,0.993657 beta-lactamase_0_L188K,beta-lactamase_0_188,TEM-1,beta-lactamase_0,P62593,0.993663,NO,188,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.166,-3.695,2.529,,,H,A,0.55,-0.3,2.739,,60.14,PHB,-1.47033,0.0500837,0.00295687,0.993663 beta-lactamase_625_K109H,beta-lactamase_625_109,TEM-1,beta-lactamase_625,P62593,0.993666,NO,109,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.734,-3.369,1.635,,0.787,G,A,2.34,2.21,7.243,,72.73,ABB,-1.63333,0.213352,0.00462493,0.993666 beta-lactamase_625_E166C,beta-lactamase_625_166,TEM-1,beta-lactamase_625,P62593,0.993669,NO,166,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.756,-5.069,3.313,,0.508,G,A,1.04,1.05,2.124,,73.08,OAH,-1.42233,0.213352,0.00512989,0.993669 kka2_1:2_G6G,kka2_1:2_6,Kka2,kka2_1:2,P00552,0.993669,NO,6,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.685,-1.685,,,,,,,,,,71.59,AOH,-1.639,0.295029,0.00204693,0.993669 beta-lactamase_156_A148N,beta-lactamase_156_148,TEM-1,beta-lactamase_156,P62593,0.993671,NO,148,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.757,-3.701,1.944,,0.379,H,A,0.46,-0.55,3.551,,72.73,PHH,-1.40167,0.111618,0.00547053,0.993671 kka2_1:1_I2V,kka2_1:1_2,Kka2,kka2_1:1,P00552,0.993675,NO,2,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.787,-1.838,0.051,,,,,,,2.329,,71.59,HHA,-1.92433,0.520039,0.00246644,0.993675 beta-lactamase_39_P165T,beta-lactamase_39_165,TEM-1,beta-lactamase_39,P62593,0.993677,NO,165,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.373,-1.281,-0.092,,0.203,T,A,0.52,-0.31,3.907,,73.78,AOA,-1.359,0.0495842,0.00549538,0.993677 beta-lactamase_625_L137A,beta-lactamase_625_137,TEM-1,beta-lactamase_625,P62593,0.993677,NO,137,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.03,-3.142,2.112,,,H,A,0.55,-0.38,1.5,,42.31,HHP,-1.58933,0.213352,0.00278599,0.993677 beta-lactamase_156_D174S,beta-lactamase_156_174,TEM-1,beta-lactamase_156,P62593,0.993679,NO,174,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.738,-3.161,2.423,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.111618,0.00125633,0.993679 kka2_1:8_W15Y,kka2_1:8_15,Kka2,kka2_1:8,P00552,0.99368,NO,15,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-1.392,-3.559,2.167,,0.01,G,A,1.51,0.15,0.827,,52.27,HHH,-2.10533,0.100394,0.00585505,0.99368 kka2_1:8_W15Y,kka2_1:8_15,Kka2,kka2_1:8,P00552,0.99368,NO,15,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-1.392,-3.559,2.167,,0.01,G,A,1.51,0.15,0.827,,52.27,HHH,-2.10533,0.100394,0.00585505,0.99368 beta-lactamase_156_L28P,beta-lactamase_156_28,TEM-1,beta-lactamase_156,P62593,0.993681,NO,28,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.579,-4.027,2.448,,0.277,H,A,0.55,-0.16,3.262,,93.01,PHH,-2.11333,0.111618,0.00359321,0.993681 beta-lactamase_39_G52E,beta-lactamase_39_52,TEM-1,beta-lactamase_39,P62593,0.993682,NO,52,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.149,-3.424,2.275,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.0495842,0.00340138,0.993682 kka2_1:8_M197C,kka2_1:8_197,Kka2,kka2_1:8,P00552,0.993697,NO,197,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.707,-4.828,3.121,,0.121,E,B,1.59,-1.19,4.408,,65.53,HHH,-1.847,0.100394,0.00921295,0.993697 kka2_1:8_M197C,kka2_1:8_197,Kka2,kka2_1:8,P00552,0.993697,NO,197,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.707,-4.828,3.121,,0.121,E,B,1.59,-1.19,4.408,,65.53,HHH,-1.847,0.100394,0.00921295,0.993697 beta-lactamase_156_K30W,beta-lactamase_156_30,TEM-1,beta-lactamase_156,P62593,0.993698,NO,30,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-2.307,-5.404,3.097,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.111618,0.00448593,0.993698 beta-lactamase_39_A84D,beta-lactamase_39_84,TEM-1,beta-lactamase_39,P62593,0.993698,NO,84,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.651,-2.92,1.269,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.0495842,0.00503822,0.993698 beta-lactamase_625_S96V,beta-lactamase_625_96,TEM-1,beta-lactamase_625,P62593,0.9937,NO,96,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.27,-3.642,1.372,,0.368,,b,0.27,0.39,5.244,,73.78,HPP,-2.019,0.213352,0.00551835,0.9937 beta-lactamase_625_M270N,beta-lactamase_625_270,TEM-1,beta-lactamase_625,P62593,0.993701,NO,270,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.213352,0.00767762,0.993701 beta-lactamase_625_M127C,beta-lactamase_625_127,TEM-1,beta-lactamase_625,P62593,0.993703,NO,127,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-2.251,-5.009,2.758,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.213352,0.00437927,0.993703 beta-lactamase_156_L205I,beta-lactamase_156_205,TEM-1,beta-lactamase_156,P62593,0.99371,NO,205,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.922,-2.97,2.048,,,H,A,0.55,-0.46,0.678,,42.31,PHH,-1.57767,0.111618,0.00255802,0.99371 beta-lactamase_156_D161C,beta-lactamase_156_161,TEM-1,beta-lactamase_156,P62593,0.993711,NO,161,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.891,-5.1,4.209,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.111618,0.000897697,0.993711 beta-lactamase_156_E46R,beta-lactamase_156_46,TEM-1,beta-lactamase_156,P62593,0.993714,NO,46,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.94,-4.04,2.1,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.111618,0.00427568,0.993714 PSD95pdz3_G356Q,PSD95pdz3_356,PSD95pdz3,PSD95pdz3,P31016,0.993715,NO,356,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.008,-3.806,2.798,4.8656,,,,,11.9575,,,,BOA,-1.22933,0.0758425,0.000623061,0.993715 beta-lactamase_156_D33L,beta-lactamase_156_33,TEM-1,beta-lactamase_156,P62593,0.993719,NO,33,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.321,-2.326,0.005,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.111618,0.00435556,0.993719 kka2_1:1_M197Q,kka2_1:1_197,Kka2,kka2_1:1,P00552,0.993721,NO,197,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.707,-4.152,2.445,,0.121,E,B,1.59,-1.19,2.097,,65.53,HHH,-1.847,0.520039,0.00921295,0.993721 beta-lactamase_625_A34W,beta-lactamase_625_34,TEM-1,beta-lactamase_625,P62593,0.993722,NO,34,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.059,-2.89,0.831,,,H,A,0.46,-0.54,3.614,,73.78,AHA,-1.74967,0.213352,0.00407913,0.993722 beta-lactamase_156_L135T,beta-lactamase_156_135,TEM-1,beta-lactamase_156,P62593,0.993725,NO,135,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.002,-3.475,2.473,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.111618,0.00244423,0.993725 beta-lactamase_39_E102A,beta-lactamase_39_102,TEM-1,beta-lactamase_39,P62593,0.993727,NO,102,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.118,-2.327,0.209,,0.722,S,B,1.04,1.82,3.87,,73.08,HAH,-1.581,0.0495842,0.00486633,0.993727 beta-lactamase_A182T,beta-lactamase_182,TEM-1,beta-lactamase,P62593,0.99373,NO,182,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.777,-2.685,0.908,4.98609,0.136,H,A,0.52,-0.66,2.032,,93.01,OHH,-1.27367,0.221079,0.00559099,0.99373 beta-lactamase_A183Q,beta-lactamase_183,TEM-1,beta-lactamase,P62593,0.99373,NO,183,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.231,-3.932,2.701,4.84712,0.155,H,A,0.55,-0.91,12.189,,77.62,HHH,-1.53367,0.221079,0.00296631,0.99373 beta-lactamase_C18W,beta-lactamase_18,TEM-1,beta-lactamase,P62593,0.99373,NO,18,C,W,CW,Special,Hydrophobic,5.07,5.89,0.82,215,121,204,83,108.5,227.8,119.3,-2.26,-3.094,0.834,,,,,,,3.995,,93.01,HOH,-2.093,0.221079,0.002536,0.99373 beta-lactamase_D113N,beta-lactamase_113,TEM-1,beta-lactamase,P62593,0.99373,NO,113,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.829,-3.682,1.853,6.04499,0.665,T,A,0.23,0.91,21.104,21.104,73.08,PAO,-1.703,0.221079,0.00474112,0.99373 beta-lactamase_E169F,beta-lactamase_169,TEM-1,beta-lactamase,P62593,0.99373,NO,169,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.23,-4.322,3.092,5.78896,0.337,,A,0.52,1,1.806,,73.08,PAH,-1.16533,0.221079,0.00400994,0.99373 beta-lactamase_E195S,beta-lactamase_195,TEM-1,beta-lactamase,P62593,0.99373,NO,195,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.186,-2.512,0.326,7.28489,1.016,S,A,1.52,0.85,2.583,,77.62,OAH,-2.02,0.221079,0.00496565,0.99373 beta-lactamase_E210Q,beta-lactamase_210,TEM-1,beta-lactamase,P62593,0.99373,NO,210,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.319,-2.627,0.308,5.7398,0.476,H,A,0.52,0.75,1.555,,77.62,HAH,-1.88567,0.221079,0.00663582,0.99373 beta-lactamase_E26K,beta-lactamase_26,TEM-1,beta-lactamase,P62593,0.99373,NO,26,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.454,-3.374,0.92,,0.54,H,A,1.04,0.98,,,93.01,OAP,-1.96167,0.221079,0.00297948,0.99373 beta-lactamase_E277R,beta-lactamase_277,TEM-1,beta-lactamase,P62593,0.99373,NO,277,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.869,-3.024,1.155,5.51786,0.545,H,A,0.52,-0.01,2.022,,77.62,HAH,-1.45367,0.221079,0.0169305,0.99373 beta-lactamase_E61W,beta-lactamase_61,TEM-1,beta-lactamase,P62593,0.99373,NO,61,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.115,-5.544,3.429,6.29701,0.775,T,a,0.52,1.29,1.975,,77.62,OAA,-1.92567,0.221079,0.00440955,0.99373 beta-lactamase_G194Q,beta-lactamase_194,TEM-1,beta-lactamase,P62593,0.99373,NO,194,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.396,-3.925,2.529,5.46622,0.276,S,b,0.77,0.36,3.593,,67.83,POA,-1.832,0.221079,0.00392163,0.99373 beta-lactamase_H156T,beta-lactamase_156,TEM-1,beta-lactamase,P62593,0.99373,NO,156,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-3.156,-2.632,-0.524,6.00284,0.753,S,A,0.72,-0.6,6.456,6.456,77.62,ABH,-1.932,0.221079,0.00468596,0.99373 beta-lactamase_H285Y,beta-lactamase_285,TEM-1,beta-lactamase,P62593,0.99373,NO,285,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-1.845,-2.622,0.777,5.64289,0.312,T,a,0.35,0.64,1.401,,72.73,BBH,-1.64567,0.221079,0.101555,0.99373 beta-lactamase_I3H,beta-lactamase_3,TEM-1,beta-lactamase,P62593,0.99373,NO,3,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-2.143,-4.694,2.551,,,,,,,3.946,,93.01,PHP,-2.21633,0.221079,0.00349304,0.99373 beta-lactamase_L199H,beta-lactamase_199,TEM-1,beta-lactamase,P62593,0.99373,NO,199,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-2.942,-4.8,1.858,5.57712,0.832,H,A,0.82,0.42,15.302,15.302,77.62,PHH,-2.32933,0.221079,0.0048649,0.99373 beta-lactamase_L28H,beta-lactamase_28,TEM-1,beta-lactamase,P62593,0.99373,NO,28,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.579,-4.838,3.259,5.42969,0.277,H,A,0.07,-0.16,19.748,19.748,93.01,PHH,-2.11333,0.221079,0.00359321,0.99373 beta-lactamase_L49Y,beta-lactamase_49,TEM-1,beta-lactamase,P62593,0.99373,NO,49,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.897,-4.158,2.261,5.86005,0.131,T,A,1.3,0.04,3.112,,64.69,AHP,-1.99233,0.221079,0.00401477,0.99373 beta-lactamase_P25E,beta-lactamase_25,TEM-1,beta-lactamase,P62593,0.99373,NO,25,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.526,-2.543,1.017,5.6134,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.221079,0.00347571,0.99373 beta-lactamase_Q37T,beta-lactamase_37,TEM-1,beta-lactamase,P62593,0.99373,NO,37,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.134,-2.508,0.374,5.69153,0.613,H,A,0.12,1.98,1.318,,73.08,APH,-2.06967,0.221079,0.00425833,0.99373 beta-lactamase_R273T,beta-lactamase_273,TEM-1,beta-lactamase,P62593,0.99373,NO,273,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.314,-3.558,1.244,,0.564,H,A,1.2,1.57,,,73.78,ABP,-1.841,0.221079,0.0077952,0.99373 beta-lactamase_R273Y,beta-lactamase_273,TEM-1,beta-lactamase,P62593,0.99373,NO,273,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.314,-4.336,2.022,,0.564,H,A,1.2,1.57,,,73.78,ABP,-1.841,0.221079,0.0077952,0.99373 beta-lactamase_R81N,beta-lactamase_81,TEM-1,beta-lactamase,P62593,0.99373,NO,81,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.466,-2.825,1.359,5.12166,0.218,H,A,0.68,1.66,1.236,,50,PBH,-1.60667,0.221079,0.00499763,0.99373 beta-lactamase_S264T,beta-lactamase_264,TEM-1,beta-lactamase,P62593,0.99373,NO,264,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.985,-1.764,-0.221,4.67475,0.04,,B,0.25,0.29,34.251,34.251,73.78,OPP,-2.19867,0.221079,0.0119399,0.99373 beta-lactamase_T187D,beta-lactamase_187,TEM-1,beta-lactamase,P62593,0.99373,NO,187,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.401,-2.769,1.368,5.11453,0.007,H,A,0.3,-1.19,1.751,,67.48,PPH,-1.69633,0.221079,0.00491782,0.99373 beta-lactamase_V106M,beta-lactamase_106,TEM-1,beta-lactamase,P62593,0.99373,NO,106,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.218,-3.026,1.808,5.23115,0.258,T,A,0.96,0.24,1.188,,72.73,OHP,-1.04933,0.221079,0.00304168,0.99373 beta-lactamase_V157A,beta-lactamase_157,TEM-1,beta-lactamase,P62593,0.99373,NO,157,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.751,-2.656,0.905,5.51733,0.308,S,a,0.96,-0.75,1.847,,69.58,BHP,-2.00767,0.221079,0.00506849,0.99373 hsp90_E590C,hsp90_590,hsp90,hsp90,P02829,0.993731,NO,590,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.818,-4.015,0,4.65049,0.021,H,A,,0.03,,,,HAO,-3.338,0.368192,0.000222939,0.993731 beta-lactamase_156_D113T,beta-lactamase_156_113,TEM-1,beta-lactamase_156,P62593,0.993734,NO,113,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.829,-2.544,0.715,,0.665,T,A,0.75,0.91,2.973,,73.08,PAO,-1.703,0.111618,0.00474112,0.993734 beta-lactamase_39_I45S,beta-lactamase_39_45,TEM-1,beta-lactamase_39,P62593,0.993734,NO,45,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-2.421,-2.717,0.296,,,E,B,0.48,-0.3,2.256,,77.62,HHA,-2.30267,0.0495842,0.00452842,0.993734 PSD95pdz3_N369M,PSD95pdz3_369,PSD95pdz3,PSD95pdz3,P31016,0.993737,NO,369,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-1.572,-4.386,2.814,5.91569,,,,,24.1262,0.44,,87.71,BPH,-1.487,0.0758425,0.000608412,0.993737 beta-lactamase_39_R189G,beta-lactamase_39_189,TEM-1,beta-lactamase_39,P62593,0.993738,NO,189,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.844,-3.504,1.66,,0.278,H,A,1.2,1.01,12.11,12.11,72.73,HBB,-1.668,0.0495842,0.0050699,0.993738 beta-lactamase_625_G265D,beta-lactamase_625_265,TEM-1,beta-lactamase_625,P62593,0.99374,NO,265,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.213352,0.00811926,0.99374 beta-lactamase_2500_T126E,beta-lactamase_2500_126,TEM-1,beta-lactamase_2500,P62593,0.993741,NO,126,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.122,-3.395,2.273,,0.05,H,A,0.22,-0.05,0.817,,44.41,HPH,-1.60467,0.361275,0.00244552,0.993741 beta-lactamase_156_A268E,beta-lactamase_156_268,TEM-1,beta-lactamase_156,P62593,0.993742,NO,268,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.111618,0.0102525,0.993742 beta-lactamase_39_H156R,beta-lactamase_39_156,TEM-1,beta-lactamase_39,P62593,0.993746,NO,156,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-3.156,-2.742,-0.414,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.0495842,0.00468596,0.993746 beta-lactamase_156_I244Q,beta-lactamase_156_244,TEM-1,beta-lactamase_156,P62593,0.993749,NO,244,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.555,-4.255,2.7,,,E,B,0.48,-0.84,1.325,,77.62,OHH,-1.385,0.111618,0.00605379,0.993749 beta-lactamase_2500_E166Q,beta-lactamase_2500_166,TEM-1,beta-lactamase_2500,P62593,0.993751,NO,166,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.756,-3.022,1.266,,0.508,G,A,1.04,1.05,2.124,,73.08,OAH,-1.42233,0.361275,0.00512989,0.993751 kka2_1:4_D33F,kka2_1:4_33,Kka2,kka2_1:4,P00552,0.99376,NO,33,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.186,-4.506,2.32,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.168804,0.00633568,0.99376 beta-lactamase_625_K144G,beta-lactamase_625_144,TEM-1,beta-lactamase_625,P62593,0.993764,NO,144,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-2.388,-2.818,0.43,,0.863,H,A,2.34,1.27,2.313,,77.62,OBA,-1.904,0.213352,0.00481141,0.993764 beta-lactamase_156_R63G,beta-lactamase_156_63,TEM-1,beta-lactamase_156,P62593,0.993765,NO,63,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-0.943,-3.426,2.483,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.111618,0.00126938,0.993765 gb1_T270C,gb1_270,gb1,gb1,P06654,0.993766,NO,270,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-3.15,-4.611,1.461,,,,,,,1.326,,45.54,HPH,-1.843,0.177985,0.00223707,0.993766 beta-lactamase_625_H24G,beta-lactamase_625_24,TEM-1,beta-lactamase_625,P62593,0.993769,NO,24,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-2.481,-2.499,0.018,,,,,,,2.708,,93.01,OBO,-2.0035,0.213352,0.00238894,0.993769 beta-lactamase_156_A282L,beta-lactamase_156_282,TEM-1,beta-lactamase_156,P62593,0.993776,NO,282,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.586,-3.183,1.597,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.111618,0.0449821,0.993776 beta-lactamase_156_H287M,beta-lactamase_156_287,TEM-1,beta-lactamase_156,P62593,0.993777,NO,287,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,,,,,,,,,,,,,BBH,-1.111,0.111618,,0.993777 beta-lactamase_0_T263H,beta-lactamase_0_263,TEM-1,beta-lactamase_0,P62593,0.993779,NO,263,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.0500837,0.0110582,0.993779 beta-lactamase_39_L199V,beta-lactamase_39_199,TEM-1,beta-lactamase_39,P62593,0.99378,NO,199,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-2.942,-2.773,-0.169,,0.832,H,A,0.55,0.42,15.504,15.504,77.62,PHH,-2.32933,0.0495842,0.0048649,0.99378 beta-lactamase_39_V72F,beta-lactamase_39_72,TEM-1,beta-lactamase_39,P62593,0.993785,NO,72,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.658,-3.023,1.365,,,H,A,0.44,-1.03,1.92,,65.73,BHH,-1.32167,0.0495842,0.00501194,0.993785 beta-lactamase_2500_S122A,beta-lactamase_2500_122,TEM-1,beta-lactamase_2500,P62593,0.993796,NO,122,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.406,-2.18,-0.226,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.361275,0.00497825,0.993796 beta-lactamase_625_E145V,beta-lactamase_625_145,TEM-1,beta-lactamase_625,P62593,0.993799,NO,145,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.357,-3.665,1.308,,0.545,H,A,1.04,0.79,2.64,,77.62,BAH,-2.069,0.213352,0.00553285,0.993799 PSD95pdz3_Q374N,PSD95pdz3_374,PSD95pdz3,PSD95pdz3,P31016,0.993801,NO,374,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-1.699,-3.13,1.431,5.38825,,,,,17.3289,,,,APH,-1.47,0.0758425,0.000372298,0.993801 beta-lactamase_2500_I261V,beta-lactamase_2500_261,TEM-1,beta-lactamase_2500,P62593,0.993808,NO,261,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.361275,0.0123091,0.993808 E1_Ubiquitin_A46G,E1_Ubiquitin_46,Uba1,E1_Ubiquitin,P0CG63,0.993811,NO,46,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.367,-2.066,0.699,,0.398,T,L,,-0.8,,,,HHO,-1.17167,0.18783,0.004233,0.993811 E1_Ubiquitin_I44Q,E1_Ubiquitin_44,Uba1,E1_Ubiquitin,P0CG63,0.993811,NO,44,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.432,-4.048,2.616,,,E,B,0.27,-1.17,4.57,,78.74,HHH,-1.25633,0.18783,0.00209731,0.993811 E1_Ubiquitin_L71P,E1_Ubiquitin_71,Uba1,E1_Ubiquitin,P0CG63,0.993811,NO,71,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.039,-3.922,2.883,,0.591,E,B,,-0.69,,,,BHB,-1.19433,0.18783,0.00148349,0.993811 E1_Ubiquitin_Q40A,E1_Ubiquitin_40,Uba1,E1_Ubiquitin,P0CG63,0.993811,NO,40,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-1.48,-3.031,1.551,,0.387,G,A,,0.03,,,,OPP,-1.365,0.18783,0.0037961,0.993811 E1_Ubiquitin_Q40T,E1_Ubiquitin_40,Uba1,E1_Ubiquitin,P0CG63,0.993811,NO,40,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-1.48,-3.375,1.895,,0.387,G,A,,0.03,,,,OPP,-1.365,0.18783,0.0037961,0.993811 E1_Ubiquitin_R42K,E1_Ubiquitin_42,Uba1,E1_Ubiquitin,P0CG63,0.993811,NO,42,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.302,-1.936,0.634,,0.244,E,B,,-0.54,,,,PBH,-1.24667,0.18783,0.00224033,0.993811 beta-lactamase_2500_G90S,beta-lactamase_2500_90,TEM-1,beta-lactamase_2500,P62593,0.993813,NO,90,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-2.091,-2.198,0.107,,0.598,T,A,0.29,0.32,1.2,,77.62,HOB,-1.52633,0.361275,0.00490273,0.993813 beta-lactamase_625_F228L,beta-lactamase_625_228,TEM-1,beta-lactamase_625,P62593,0.993813,NO,228,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-2.342,-3.312,0.97,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.213352,0.0046669,0.993813 beta-lactamase_39_P143K,beta-lactamase_39_143,TEM-1,beta-lactamase_39,P62593,0.993816,NO,143,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.967,-3.581,2.614,,0.075,H,A,0.52,-0.37,0.976,,66.78,OOB,-1.354,0.0495842,0.00114551,0.993816 beta-lactamase_39_G265M,beta-lactamase_39_265,TEM-1,beta-lactamase_39,P62593,0.993819,NO,265,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.0495842,0.00811926,0.993819 beta-lactamase_156_A222N,beta-lactamase_156_222,TEM-1,beta-lactamase_156,P62593,0.99382,NO,222,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.103,-3.751,1.648,,0.233,H,A,0.46,-0.25,2.461,,77.62,PHH,-1.63733,0.111618,0.00466094,0.99382 beta-lactamase_A225R,beta-lactamase_225,TEM-1,beta-lactamase,P62593,0.99382,NO,225,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.845,-2.864,1.019,6.5181,1,T,B,0.58,-0.38,4.077,,74.48,OHO,-1.39967,0.221079,0.00465057,0.99382 beta-lactamase_39_Q88V,beta-lactamase_39_88,TEM-1,beta-lactamase_39,P62593,0.993821,NO,88,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.086,-3.621,1.535,,0.807,,B,0.64,2.03,11.108,11.108,77.62,APH,-1.53433,0.0495842,0.00504167,0.993821 beta-lactamase_625_G216L,beta-lactamase_625_216,TEM-1,beta-lactamase_625,P62593,0.993824,NO,216,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.477,-3.78,2.303,,0.437,I,A,0.29,-0.58,1.718,,74.48,HOO,-1.68067,0.213352,0.00639568,0.993824 beta-lactamase_156_T186E,beta-lactamase_156_186,TEM-1,beta-lactamase_156,P62593,0.993826,NO,186,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.522,-2.494,-0.028,,0.396,H,A,0.22,-0.28,16.606,16.606,77.62,HPP,-1.77633,0.111618,0.00485034,0.993826 beta-lactamase_39_A247Q,beta-lactamase_39_247,TEM-1,beta-lactamase_39,P62593,0.993841,NO,247,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.0495842,0.00611275,0.993841 beta-lactamase_156_P224T,beta-lactamase_156_224,TEM-1,beta-lactamase_156,P62593,0.993843,NO,224,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.893,-3.414,2.521,,0.383,,B,0.52,-0.3,0.383,,74.48,HOH,-1.26433,0.111618,0.00189564,0.993843 beta-lactamase_156_R202Y,beta-lactamase_156_202,TEM-1,beta-lactamase_156,P62593,0.993843,NO,202,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.292,-4.182,2.89,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.111618,0.00321899,0.993843 beta-lactamase_39_T193G,beta-lactamase_39_193,TEM-1,beta-lactamase_39,P62593,0.993843,NO,193,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.914,-3.548,1.634,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.0495842,0.00482669,0.993843 beta-lactamase_625_R162H,beta-lactamase_625_162,TEM-1,beta-lactamase_625,P62593,0.993846,NO,162,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.016,-4.37,3.354,,0.124,S,B,1.2,-0.37,1.445,,64.69,ABH,-1.25,0.213352,0.000561334,0.993846 beta-lactamase_625_D33Q,beta-lactamase_625_33,TEM-1,beta-lactamase_625,P62593,0.993848,NO,33,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.321,-2.638,0.317,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.213352,0.00435556,0.993848 beta-lactamase_39_T264S,beta-lactamase_39_264,TEM-1,beta-lactamase_39,P62593,0.993851,NO,264,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.985,-1.764,-0.221,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.0495842,0.0119399,0.993851 beta-lactamase_39_G154Q,beta-lactamase_39_154,TEM-1,beta-lactamase_39,P62593,0.993855,NO,154,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.823,-4.083,3.26,,0.54,T,l,0.29,-0.56,1.151,,64.69,HOA,-1.635,0.0495842,0.00180205,0.993855 beta-lactamase_39_I261W,beta-lactamase_39_261,TEM-1,beta-lactamase_39,P62593,0.993859,NO,261,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.0495842,0.0123091,0.993859 beta-lactamase_625_M180I,beta-lactamase_625_180,TEM-1,beta-lactamase_625,P62593,0.993861,NO,180,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-2.795,-3.664,0.869,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.213352,0.00552048,0.993861 beta-lactamase_156_M127G,beta-lactamase_156_127,TEM-1,beta-lactamase_156,P62593,0.993862,NO,127,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-2.251,-3.785,1.534,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.111618,0.00437927,0.993862 beta-lactamase_39_H156G,beta-lactamase_39_156,TEM-1,beta-lactamase_39,P62593,0.993862,NO,156,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-3.156,-2.688,-0.468,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.0495842,0.00468596,0.993862 beta-lactamase_156_E169T,beta-lactamase_156_169,TEM-1,beta-lactamase_156,P62593,0.993868,NO,169,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.23,-2.43,1.2,,0.337,,A,1.04,1,3.516,,73.08,PAH,-1.16533,0.111618,0.00400994,0.993868 beta-lactamase_156_G234S,beta-lactamase_156_234,TEM-1,beta-lactamase_156,P62593,0.993869,NO,234,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.62,-3.161,2.541,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.111618,0.000889577,0.993869 PSD95pdz3_K393C,PSD95pdz3_393,PSD95pdz3,PSD95pdz3,P31016,0.993872,NO,393,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.416,-4.769,3.353,5.42682,,,,,22.0122,,,,HBO,-1.4265,0.0758425,0.000879298,0.993872 beta-lactamase_0_A77Y,beta-lactamase_0_77,TEM-1,beta-lactamase_0,P62593,0.993887,NO,77,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.234,-4.173,2.939,,0.039,H,A,0.46,-0.56,2.591,,64.34,OHH,-1.294,0.0500837,0.00282362,0.993887 beta-lactamase_156_N98R,beta-lactamase_156_98,TEM-1,beta-lactamase_156,P62593,0.993889,NO,98,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-2.973,-2.618,-0.355,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.111618,0.00505389,0.993889 beta-lactamase_156_A222C,beta-lactamase_156_222,TEM-1,beta-lactamase_156,P62593,0.99389,NO,222,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.103,-4.939,2.836,,0.233,H,A,0.46,-0.25,2.461,,77.62,PHH,-1.63733,0.111618,0.00466094,0.99389 beta-lactamase_39_D177C,beta-lactamase_39_177,TEM-1,beta-lactamase_39,P62593,0.993894,NO,177,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.967,-5.073,4.106,,0.006,T,L,0.75,-1.02,3.536,,64.69,BAP,-0.873667,0.0495842,0.000864022,0.993894 beta-lactamase_156_Y95H,beta-lactamase_156_95,TEM-1,beta-lactamase_156,P62593,0.993898,NO,95,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-1.715,-3.182,1.467,,0.122,,b,0.21,-0.37,2.341,,77.62,BHP,-2.16167,0.111618,0.00479449,0.993898 beta-lactamase_2500_L199R,beta-lactamase_2500_199,TEM-1,beta-lactamase_2500,P62593,0.993899,NO,199,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-2.942,-3.181,0.239,,0.832,H,A,0.55,0.42,15.504,15.504,77.62,PHH,-2.32933,0.361275,0.0048649,0.993899 kka2_1:4_S114L,kka2_1:4_114,Kka2,kka2_1:4,P00552,0.993904,NO,114,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.527,-3.038,0.511,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.168804,0.00705262,0.993904 beta-lactamase_156_Y103W,beta-lactamase_156_103,TEM-1,beta-lactamase_156,P62593,0.993909,NO,103,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-1.33,-2.453,1.123,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.111618,0.00443048,0.993909 beta-lactamase_2500_L284V,beta-lactamase_2500_284,TEM-1,beta-lactamase_2500,P62593,0.993911,NO,284,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.361275,0.0686156,0.993911 beta-lactamase_156_N98L,beta-lactamase_156_98,TEM-1,beta-lactamase_156,P62593,0.993914,NO,98,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-2.973,-3.59,0.617,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.111618,0.00505389,0.993914 beta-lactamase_156_L38S,beta-lactamase_156_38,TEM-1,beta-lactamase_156,P62593,0.993918,NO,38,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.343,-2.597,1.254,,0.088,H,A,0.55,0.2,13.556,13.556,64.34,PHO,-1.78033,0.111618,0.00373244,0.993918 beta-lactamase_625_K109D,beta-lactamase_625_109,TEM-1,beta-lactamase_625,P62593,0.993928,NO,109,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.734,-2.919,1.185,,0.787,G,A,2.34,2.21,7.243,,72.73,ABB,-1.63333,0.213352,0.00462493,0.993928 beta-lactamase_39_T264F,beta-lactamase_39_264,TEM-1,beta-lactamase_39,P62593,0.993929,NO,264,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.0495842,0.0119399,0.993929 beta-lactamase_625_V101I,beta-lactamase_625_101,TEM-1,beta-lactamase_625,P62593,0.99393,NO,101,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.295,-2.207,0.912,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.213352,0.00374492,0.99393 gb1_N234L,gb1_234,gb1,gb1,P06654,0.993933,NO,234,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-2.055,-3.258,1.203,,,,,,,1.235,,45.54,HPO,-2.05067,0.177985,0.00242189,0.993933 gb1_T279E,gb1_279,gb1,gb1,P06654,0.993933,NO,279,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.32,-3.389,2.069,,,,,,,0.529,,35.71,HPH,-1.50067,0.177985,0.00421454,0.993933 beta-lactamase_39_A211Y,beta-lactamase_39_211,TEM-1,beta-lactamase_39,P62593,0.993935,NO,211,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.896,-4.344,2.448,,0.369,T,A,0.46,-0.69,1.419,,77.62,AHA,-1.94633,0.0495842,0.00648183,0.993935 beta-lactamase_625_A170S,beta-lactamase_625_170,TEM-1,beta-lactamase_625,P62593,0.993935,NO,170,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.237,-3.188,1.951,,0.126,,L,0.46,-0.35,3.626,,64.69,AHH,-1.63267,0.213352,0.00431903,0.993935 beta-lactamase_625_R118M,beta-lactamase_625_118,TEM-1,beta-lactamase_625,P62593,0.993937,NO,118,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.413,-4.747,2.334,,0.457,H,A,1.2,1.39,2.144,,77.62,HBA,-1.785,0.213352,0.00538794,0.993937 beta-lactamase_2500_A84V,beta-lactamase_2500_84,TEM-1,beta-lactamase_2500,P62593,0.993939,NO,84,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.651,-2.943,1.292,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.361275,0.00503822,0.993939 beta-lactamase_156_N152E,beta-lactamase_156_152,TEM-1,beta-lactamase_156,P62593,0.993941,NO,152,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-2.757,-2.679,-0.078,,0.863,H,A,0.61,0.92,4.038,,77.62,BPH,-2.97,0.111618,0.00471429,0.993941 beta-lactamase_156_W163N,beta-lactamase_156_163,TEM-1,beta-lactamase_156,P62593,0.993945,NO,163,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-1.843,-2.852,1.009,,0.467,,B,0.47,-0.5,15.095,15.095,63.99,BHA,-1.269,0.111618,0.00418955,0.993945 beta-lactamase_39_L167E,beta-lactamase_39_167,TEM-1,beta-lactamase_39,P62593,0.993949,NO,167,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.138,-3.783,2.645,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.0495842,0.00303566,0.993949 beta-lactamase_156_R242S,beta-lactamase_156_242,TEM-1,beta-lactamase_156,P62593,0.993954,NO,242,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.111618,0.00452879,0.993954 beta-lactamase_39_G114K,beta-lactamase_39_114,TEM-1,beta-lactamase_39,P62593,0.993954,NO,114,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.094,-3.566,2.472,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.0495842,0.00224919,0.993954 beta-lactamase_156_S57D,beta-lactamase_156_57,TEM-1,beta-lactamase_156,P62593,0.993958,NO,57,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.918,-3.634,1.716,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.111618,0.00492804,0.993958 beta-lactamase_K144Q,beta-lactamase_144,TEM-1,beta-lactamase,P62593,0.993958,NO,144,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-2.388,-2.378,-0.01,6.02507,0.863,H,A,2.81,1.27,0.515,,77.62,OBA,-1.904,0.221079,0.00481141,0.993958 beta-lactamase_2500_F58Y,beta-lactamase_2500_58,TEM-1,beta-lactamase_2500,P62593,0.993959,NO,58,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-2.914,-1.89,-1.024,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.361275,0.00523369,0.993959 beta-lactamase_2500_Q88V,beta-lactamase_2500_88,TEM-1,beta-lactamase_2500,P62593,0.993966,NO,88,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.086,-3.621,1.535,,0.807,,B,0.64,2.03,1.84,,77.62,APH,-1.53433,0.361275,0.00504167,0.993966 beta-lactamase_39_H24N,beta-lactamase_39_24,TEM-1,beta-lactamase_39,P62593,0.993968,NO,24,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-2.481,-3.496,1.015,,,,,,,2.708,,93.01,OBO,-2.0035,0.0495842,0.00238894,0.993968 beta-lactamase_39_E175K,beta-lactamase_39_175,TEM-1,beta-lactamase_39,P62593,0.993972,NO,175,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.336,-2.673,0.337,,0.551,,A,1.04,1.05,3.676,,77.62,AAB,-1.31233,0.0495842,0.00482205,0.993972 beta-lactamase_156_V78L,beta-lactamase_156_78,TEM-1,beta-lactamase_156,P62593,0.99398,NO,78,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.459,-1.714,0.255,,,H,A,0.44,-0.47,1.132,,63.64,HHH,-1.17833,0.111618,0.00492501,0.99398 beta-lactamase_156_Q204S,beta-lactamase_156_204,TEM-1,beta-lactamase_156,P62593,0.993981,NO,204,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-1.382,-3.344,1.962,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.111618,0.00364106,0.993981 beta-lactamase_39_A225S,beta-lactamase_39_225,TEM-1,beta-lactamase_39,P62593,0.993982,NO,225,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.845,-2.863,1.018,,1,T,B,0.46,-0.38,9.874,9.874,74.48,OHO,-1.39967,0.0495842,0.00465057,0.993982 beta-lactamase_39_G85H,beta-lactamase_39_85,TEM-1,beta-lactamase_39,P62593,0.993985,NO,85,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.011,-4.646,3.635,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.0495842,0.00252173,0.993985 beta-lactamase_39_L199C,beta-lactamase_39_199,TEM-1,beta-lactamase_39,P62593,0.993985,NO,199,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-2.942,-5.078,2.136,,0.832,H,A,0.55,0.42,15.504,15.504,77.62,PHH,-2.32933,0.0495842,0.0048649,0.993985 beta-lactamase_39_L111V,beta-lactamase_39_111,TEM-1,beta-lactamase_39,P62593,0.993992,NO,111,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.76,-1.731,-0.029,,0.328,T,A,0.55,0.93,4.334,,64.34,BHP,-1.884,0.0495842,0.00480671,0.993992 beta-lactamase_156_T269A,beta-lactamase_156_269,TEM-1,beta-lactamase_156,P62593,0.994005,NO,269,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.111618,0.00950944,0.994005 beta-lactamase_625_T187F,beta-lactamase_625_187,TEM-1,beta-lactamase_625,P62593,0.994008,NO,187,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.401,-4.141,2.74,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.213352,0.00491782,0.994008 beta-lactamase_625_D113G,beta-lactamase_625_113,TEM-1,beta-lactamase_625,P62593,0.99401,NO,113,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.829,-2.42,0.591,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.213352,0.00474112,0.99401 beta-lactamase_2500_K286S,beta-lactamase_2500_286,TEM-1,beta-lactamase_2500,P62593,0.994012,NO,286,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.361275,,0.994012 beta-lactamase_156_A123S,beta-lactamase_156_123,TEM-1,beta-lactamase_156,P62593,0.994014,NO,123,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.834,-3.019,2.185,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.111618,0.0010157,0.994014 WW_domain_R187V,WW_domain_187,Yap65,WW_domain,P46937,0.994014,NO,187,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.402,-3.524,2.122,5.05189,,,,,,3.431,,78.57,PBH,-1.362,0.153962,0.00171149,0.994014 kka2_1:4_E111R,kka2_1:4_111,Kka2,kka2_1:4,P00552,0.994016,NO,111,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.28,-2.316,0.036,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.168804,0.00746789,0.994016 beta-lactamase_625_L160F,beta-lactamase_625_160,TEM-1,beta-lactamase_625,P62593,0.994017,NO,160,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.977,-3.681,2.704,,0.022,,B,0.55,-0.6,0.237,,44.41,BHA,-0.936,0.213352,0.00193775,0.994017 beta-lactamase_625_S256N,beta-lactamase_625_256,TEM-1,beta-lactamase_625,P62593,0.994019,NO,256,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.213352,0.00710634,0.994019 kka2_1:8_G21I,kka2_1:8_21,Kka2,kka2_1:8,P00552,0.99402,NO,21,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.368,-4.201,2.833,,0.586,T,l,0.29,-0.75,4.889,,71.59,HOH,-2.10167,0.100394,0.00709648,0.99402 kka2_1:8_G21I,kka2_1:8_21,Kka2,kka2_1:8,P00552,0.99402,NO,21,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.368,-4.201,2.833,,0.586,T,l,0.29,-0.75,4.889,,71.59,HOH,-2.10167,0.100394,0.00709648,0.99402 beta-lactamase_2500_S256K,beta-lactamase_2500_256,TEM-1,beta-lactamase_2500,P62593,0.994021,NO,256,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.361275,0.00710634,0.994021 beta-lactamase_S80F,beta-lactamase_80,TEM-1,beta-lactamase,P62593,0.994021,NO,80,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.029,-4.287,2.258,5.23748,0.192,H,A,0.25,0.46,2.256,,77.62,HPB,-1.44567,0.221079,0.00565569,0.994021 beta-lactamase_625_R41A,beta-lactamase_625_41,TEM-1,beta-lactamase_625,P62593,0.994024,NO,41,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-0.942,-3.041,2.099,,0.321,E,B,1.2,-0.07,1.186,,65.03,HBH,-1.30267,0.213352,0.00123327,0.994024 kka2_1:2_G234G,kka2_1:2_234,Kka2,kka2_1:2,P00552,0.994027,NO,234,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-2.9,-2.9,,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.295029,0.00984449,0.994027 beta-lactamase_156_G141T,beta-lactamase_156_141,TEM-1,beta-lactamase_156,P62593,0.99403,NO,141,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.828,-3.647,2.819,,0.575,T,l,0.29,-0.28,0.198,,64.69,HOO,-1.08933,0.111618,0.0012419,0.99403 beta-lactamase_2500_K53R,beta-lactamase_2500_53,TEM-1,beta-lactamase_2500,P62593,0.99403,NO,53,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-2.313,-2.027,-0.286,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.361275,0.00383383,0.99403 beta-lactamase_156_V106T,beta-lactamase_156_106,TEM-1,beta-lactamase_156,P62593,0.994032,NO,106,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.218,-3.428,2.21,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.111618,0.00304168,0.994032 beta-lactamase_2500_R189L,beta-lactamase_2500_189,TEM-1,beta-lactamase_2500,P62593,0.994033,NO,189,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.844,-3.611,1.767,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.361275,0.0050699,0.994033 beta-lactamase_39_V72S,beta-lactamase_39_72,TEM-1,beta-lactamase_39,P62593,0.994033,NO,72,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.658,-3.477,1.819,,,H,A,0.44,-1.03,1.92,,65.73,BHH,-1.32167,0.0495842,0.00501194,0.994033 beta-lactamase_156_D161T,beta-lactamase_156_161,TEM-1,beta-lactamase_156,P62593,0.994035,NO,161,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.891,-3.414,2.523,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.111618,0.000897697,0.994035 beta-lactamase_156_R239I,beta-lactamase_156_239,TEM-1,beta-lactamase_156,P62593,0.994038,NO,239,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.111618,0.00213852,0.994038 beta-lactamase_2500_K144G,beta-lactamase_2500_144,TEM-1,beta-lactamase_2500,P62593,0.99404,NO,144,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-2.388,-2.818,0.43,,0.863,H,A,2.34,1.27,0.515,,77.62,OBA,-1.904,0.361275,0.00481141,0.99404 beta-lactamase_625_R81T,beta-lactamase_625_81,TEM-1,beta-lactamase_625,P62593,0.994041,NO,81,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.466,-3.547,2.081,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.213352,0.00499763,0.994041 beta-lactamase_625_R92E,beta-lactamase_625_92,TEM-1,beta-lactamase_625,P62593,0.994041,NO,92,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.718,-2.624,0.906,,0.479,E,B,1.2,1.36,3.069,,65.38,BBH,-1.50367,0.213352,0.00429626,0.994041 beta-lactamase_0_T178P,beta-lactamase_0_178,TEM-1,beta-lactamase_0,P62593,0.994044,NO,178,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-0.791,-3.655,2.864,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.0500837,0.000684366,0.994044 beta-lactamase_39_E175N,beta-lactamase_39_175,TEM-1,beta-lactamase_39,P62593,0.994044,NO,175,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.336,-3.857,1.521,,0.551,,A,1.04,1.05,3.676,,77.62,AAB,-1.31233,0.0495842,0.00482205,0.994044 beta-lactamase_39_N50A,beta-lactamase_39_50,TEM-1,beta-lactamase_39,P62593,0.994045,NO,50,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-2.979,-1.868,-1.111,,0.912,T,A,0.61,1.24,10.736,,77.62,HPP,-2.134,0.0495842,0.0047211,0.994045 beta-lactamase_156_A124M,beta-lactamase_156_124,TEM-1,beta-lactamase_156,P62593,0.994048,NO,124,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.181,-4.519,3.338,,,H,A,0.46,-0.9,2.027,,64.34,HHH,-1.152,0.111618,0.00481399,0.994048 beta-lactamase_625_H24Q,beta-lactamase_625_24,TEM-1,beta-lactamase_625,P62593,0.994048,NO,24,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-2.481,-2.604,0.123,,,,,,,2.708,,93.01,OBO,-2.0035,0.213352,0.00238894,0.994048 beta-lactamase_625_L205V,beta-lactamase_625_205,TEM-1,beta-lactamase_625,P62593,0.994052,NO,205,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.922,-2.938,2.016,,,H,A,0.55,-0.46,3.782,,42.31,PHH,-1.57767,0.213352,0.00255802,0.994052 beta-lactamase_625_L199S,beta-lactamase_625_199,TEM-1,beta-lactamase_625,P62593,0.994054,NO,199,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-2.942,-2.568,-0.374,,0.832,H,A,0.55,0.42,1.552,,77.62,PHH,-2.32933,0.213352,0.0048649,0.994054 beta-lactamase_I3Y,beta-lactamase_3,TEM-1,beta-lactamase,P62593,0.994055,NO,3,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-2.143,-3.974,1.831,,,,,,,3.946,,93.01,PHP,-2.21633,0.221079,0.00349304,0.994055 beta-lactamase_39_L111H,beta-lactamase_39_111,TEM-1,beta-lactamase_39,P62593,0.994059,NO,111,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.76,-4.922,3.162,,0.328,T,A,0.55,0.93,4.334,,64.34,BHP,-1.884,0.0495842,0.00480671,0.994059 Pab1_E176P,Pab1_176,Pab1,Pab1,P04147,0.994061,NO,176,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.003,-2.561,0.558,,,,,,,,,,AAO,-2.09933,0.175299,0.00264426,0.994061 beta-lactamase_625_S96K,beta-lactamase_625_96,TEM-1,beta-lactamase_625,P62593,0.994066,NO,96,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.27,-2.895,0.625,,0.368,,b,0.27,0.39,5.244,,73.78,HPP,-2.019,0.213352,0.00551835,0.994066 beta-lactamase_39_A282E,beta-lactamase_39_282,TEM-1,beta-lactamase_39,P62593,0.99407,NO,282,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.0495842,0.0449821,0.99407 beta-lactamase_39_G194V,beta-lactamase_39_194,TEM-1,beta-lactamase_39,P62593,0.99407,NO,194,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.396,-3.736,2.34,,0.276,S,b,0.29,0.36,4.852,,67.83,POA,-1.832,0.0495842,0.00392163,0.99407 beta-lactamase_156_P25R,beta-lactamase_156_25,TEM-1,beta-lactamase_156,P62593,0.994071,NO,25,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.526,-3.8,2.274,,0.624,H,A,0.52,0.14,1.079,,73.08,BOA,-2.15367,0.111618,0.00347571,0.994071 beta-lactamase_2500_E169G,beta-lactamase_2500_169,TEM-1,beta-lactamase_2500,P62593,0.994072,NO,169,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.23,-3.348,2.118,,0.337,,A,1.04,1,1.806,,73.08,PAH,-1.16533,0.361275,0.00400994,0.994072 Pab1_N192Q,Pab1_192,Pab1,Pab1,P04147,0.994073,NO,192,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-1.079,-3.491,2.412,,0.619,T,l,,2.28,,,,HPO,-1.231,0.175299,0.000273498,0.994073 beta-lactamase_P60Q,beta-lactamase_60,TEM-1,beta-lactamase,P62593,0.994074,NO,60,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-2.469,-3.986,1.517,5.51353,0.256,T,A,0.73,-0.56,3.653,,77.62,BOA,-1.97633,0.221079,0.00521318,0.994074 beta-lactamase_Q88T,beta-lactamase_88,TEM-1,beta-lactamase,P62593,0.994074,NO,88,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.086,-2.693,0.607,5.8056,0.807,,B,0.12,2.03,1.84,,77.62,APH,-1.53433,0.221079,0.00504167,0.994074 beta-lactamase_39_C121Q,beta-lactamase_39_121,TEM-1,beta-lactamase_39,P62593,0.994075,NO,121,C,Q,CQ,Special,Polar,5.07,6.24429,1.17429,154,121,146,25,108.5,143.8,35.3,-0.953,-4.222,3.269,,,H,A,0.46,-0.81,7.644,,63.29,HOP,-1.46767,0.0495842,0.000744322,0.994075 kka2_1:4_E182H,kka2_1:4_182,Kka2,kka2_1:4,P00552,0.994078,NO,182,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.516,-2.568,1.052,,0.326,.,B,1.04,0.75,4.755,,65.53,OAA,-1.806,0.168804,0.00641548,0.994078 beta-lactamase_39_V214Q,beta-lactamase_39_214,TEM-1,beta-lactamase_39,P62593,0.994081,NO,214,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.299,-4.141,2.842,,0.375,S,A,0.44,-0.44,18.838,18.838,74.48,BHH,-1.53733,0.0495842,0.00628442,0.994081 beta-lactamase_156_E145A,beta-lactamase_156_145,TEM-1,beta-lactamase_156,P62593,0.994082,NO,145,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.357,-1.901,-0.456,,0.545,H,A,1.04,0.79,3.661,,77.62,BAH,-2.069,0.111618,0.00553285,0.994082 beta-lactamase_625_Q37G,beta-lactamase_625_37,TEM-1,beta-lactamase_625,P62593,0.994083,NO,37,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.134,-3.507,1.373,,0.613,H,A,0.64,1.98,1.318,,73.08,APH,-2.06967,0.213352,0.00425833,0.994083 beta-lactamase_39_G52V,beta-lactamase_39_52,TEM-1,beta-lactamase_39,P62593,0.994084,NO,52,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.149,-3.738,2.589,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.0495842,0.00340138,0.994084 beta-lactamase_625_L219V,beta-lactamase_625_219,TEM-1,beta-lactamase_625,P62593,0.994084,NO,219,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.313,-2.847,1.534,,,I,A,0.55,-0.51,5.627,,74.48,HHB,-1.21533,0.213352,0.00664345,0.994084 beta-lactamase_2500_D252G,beta-lactamase_2500_252,TEM-1,beta-lactamase_2500,P62593,0.994088,NO,252,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.94,,,,0.766,,B,1.59,1.16,,,67.83,OAO,-2.0965,0.361275,0.00575769,0.994088 beta-lactamase_625_G226P,beta-lactamase_625_226,TEM-1,beta-lactamase_625,P62593,0.99409,NO,226,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.461,-3.96,2.499,,0.701,T,l,0.29,-0.25,3.199,,74.48,HOH,-1.42933,0.213352,0.00665294,0.99409 beta-lactamase_625_V82R,beta-lactamase_625_82,TEM-1,beta-lactamase_625,P62593,0.994092,NO,82,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.325,-4.101,2.776,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.213352,0.00397046,0.994092 beta-lactamase_2500_N98Y,beta-lactamase_2500_98,TEM-1,beta-lactamase_2500,P62593,0.994098,NO,98,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-2.973,-4.22,1.247,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.361275,0.00505389,0.994098 beta-lactamase_I244I,beta-lactamase_244,TEM-1,beta-lactamase,P62593,0.994103,NO,244,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.555,-1.555,,5.35885,,E,B,0.01,-0.84,0.379,,77.62,HHH,-1.385,0.221079,0.00605379,0.994103 beta-lactamase_E164E,beta-lactamase_164,TEM-1,beta-lactamase,P62593,0.994105,NO,164,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-0.948,-0.948,,5.3334,0.011,T,B,1.62,-0.4,1.055,,64.69,HAO,-1.388,0.221079,0.00137286,0.994105 beta-lactamase_625_R176M,beta-lactamase_625_176,TEM-1,beta-lactamase_625,P62593,0.994108,NO,176,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-0.863,-4.48,3.617,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.213352,0.00105554,0.994108 beta-lactamase_625_R242S,beta-lactamase_625_242,TEM-1,beta-lactamase_625,P62593,0.994113,NO,242,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.213352,0.00452879,0.994113 beta-lactamase_0_L248S,beta-lactamase_0_248,TEM-1,beta-lactamase_0,P62593,0.994114,NO,248,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.0500837,0.00428493,0.994114 beta-lactamase_156_T147D,beta-lactamase_156_147,TEM-1,beta-lactamase_156,P62593,0.994115,NO,147,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.149,-3.491,2.342,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.111618,0.00226017,0.994115 beta-lactamase_156_N98W,beta-lactamase_156_98,TEM-1,beta-lactamase_156,P62593,0.994118,NO,98,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-2.973,-5.455,2.482,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.111618,0.00505389,0.994118 beta-lactamase_625_T187G,beta-lactamase_625_187,TEM-1,beta-lactamase_625,P62593,0.994123,NO,187,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.401,-3.394,1.993,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.213352,0.00491782,0.994123 beta-lactamase_2500_E145S,beta-lactamase_2500_145,TEM-1,beta-lactamase_2500,P62593,0.994124,NO,145,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.357,-2.669,0.312,,0.545,H,A,1.04,0.79,2.124,,77.62,BAH,-2.069,0.361275,0.00553285,0.994124 beta-lactamase_A183V,beta-lactamase_183,TEM-1,beta-lactamase,P62593,0.994126,NO,183,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.231,-3.28,2.049,4.84712,0.155,H,A,0.55,-0.91,12.189,,77.62,HHH,-1.53367,0.221079,0.00296631,0.994126 Pab1_K180T,Pab1_180,Pab1,Pab1,P04147,0.994128,NO,180,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.945,-3.403,1.458,,,,,,,,,,HBA,-1.575,0.175299,0.00295933,0.994128 kka2_1:2_Q252M,kka2_1:2_252,Kka2,kka2_1:2,P00552,0.994129,NO,252,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.63,-4.83,2.2,,0.906,H,A,0.64,0.35,5.613,,92.05,PPB,-2.20733,0.295029,0.0121001,0.994129 beta-lactamase_2500_T193F,beta-lactamase_2500_193,TEM-1,beta-lactamase_2500,P62593,0.994131,NO,193,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.914,-2.368,0.454,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.361275,0.00482669,0.994131 beta-lactamase_39_Q37P,beta-lactamase_39_37,TEM-1,beta-lactamase_39,P62593,0.994132,NO,37,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.134,-3.965,1.831,,0.613,H,A,0.64,1.98,22.282,22.282,73.08,APH,-2.06967,0.0495842,0.00425833,0.994132 beta-lactamase_39_R81W,beta-lactamase_39_81,TEM-1,beta-lactamase_39,P62593,0.994133,NO,81,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.466,-5.415,3.949,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.0495842,0.00499763,0.994133 beta-lactamase_156_L150N,beta-lactamase_156_150,TEM-1,beta-lactamase_156,P62593,0.994136,NO,150,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.326,-4.088,2.762,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.111618,0.00463171,0.994136 beta-lactamase_39_H24V,beta-lactamase_39_24,TEM-1,beta-lactamase_39,P62593,0.994138,NO,24,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-2.481,-3.524,1.043,,,,,,,2.708,,93.01,OBO,-2.0035,0.0495842,0.00238894,0.994138 beta-lactamase_156_V82T,beta-lactamase_156_82,TEM-1,beta-lactamase_156,P62593,0.994139,NO,82,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.325,-3.392,2.067,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.111618,0.00397046,0.994139 beta-lactamase_39_V260S,beta-lactamase_39_260,TEM-1,beta-lactamase_39,P62593,0.99414,NO,260,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.0495842,0.00471757,0.99414 beta-lactamase_156_S51R,beta-lactamase_156_51,TEM-1,beta-lactamase_156,P62593,0.994142,NO,51,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.526,-2.956,1.43,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.111618,0.00504821,0.994142 beta-lactamase_625_T116D,beta-lactamase_625_116,TEM-1,beta-lactamase_625,P62593,0.994143,NO,116,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.28,-3.524,2.244,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.213352,0.00336175,0.994143 beta-lactamase_156_E166V,beta-lactamase_156_166,TEM-1,beta-lactamase_156,P62593,0.994145,NO,166,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.756,-2.896,1.14,,0.508,G,A,1.04,1.05,2.393,,73.08,OAH,-1.42233,0.111618,0.00512989,0.994145 beta-lactamase_625_K144V,beta-lactamase_625_144,TEM-1,beta-lactamase_625,P62593,0.994146,NO,144,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-2.388,-3.003,0.615,,0.863,H,A,2.34,1.27,2.313,,77.62,OBA,-1.904,0.213352,0.00481141,0.994146 beta-lactamase_156_Q97N,beta-lactamase_156_97,TEM-1,beta-lactamase_156,P62593,0.994153,NO,97,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.072,-3.773,1.701,,0.823,G,A,0.64,2.42,4.457,,77.62,PPP,-2.43833,0.111618,0.0045116,0.994153 beta-lactamase_156_A247E,beta-lactamase_156_247,TEM-1,beta-lactamase_156,P62593,0.994154,NO,247,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.111618,0.00611275,0.994154 beta-lactamase_39_P165Y,beta-lactamase_39_165,TEM-1,beta-lactamase_39,P62593,0.994154,NO,165,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.373,-4.331,2.958,,0.203,T,A,0.52,-0.31,3.907,,73.78,AOA,-1.359,0.0495842,0.00549538,0.994154 PSD95pdz3_P346R,PSD95pdz3_346,PSD95pdz3,PSD95pdz3,P31016,0.994154,NO,346,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.236,-3.615,2.379,5.02406,,,,,14.6629,,,,OOH,-1.18367,0.0758425,0.000758563,0.994154 beta-lactamase_625_D271Q,beta-lactamase_625_271,TEM-1,beta-lactamase_625,P62593,0.994156,NO,271,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.213352,0.00752082,0.994156 beta-lactamase_39_E119K,beta-lactamase_39_119,TEM-1,beta-lactamase_39,P62593,0.994158,NO,119,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.412,-3.343,1.931,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.0495842,0.00386966,0.994158 beta-lactamase_156_T198K,beta-lactamase_156_198,TEM-1,beta-lactamase_156,P62593,0.994159,NO,198,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.168,-2.548,0.38,,0.489,,B,0.22,-0.13,10.771,10.771,73.78,HPH,-1.98767,0.111618,0.004311,0.994159 beta-lactamase_156_T126V,beta-lactamase_156_126,TEM-1,beta-lactamase_156,P62593,0.99416,NO,126,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.122,-3.336,2.214,,0.05,H,A,0.22,-0.05,1.14,,44.41,HPH,-1.60467,0.111618,0.00244552,0.99416 beta-lactamase_156_Y95P,beta-lactamase_156_95,TEM-1,beta-lactamase_156,P62593,0.99416,NO,95,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-1.715,-4.285,2.57,,0.122,,b,0.21,-0.37,2.341,,77.62,BHP,-2.16167,0.111618,0.00479449,0.99416 Pab1_E174G,Pab1_174,Pab1,Pab1,P04147,0.99416,NO,174,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.422,-3.267,1.845,,0.578,S,A,,0.38,,,,HAA,-1.65133,0.175299,0.00077863,0.99416 beta-lactamase_39_Q86G,beta-lactamase_39_86,TEM-1,beta-lactamase_39,P62593,0.994161,NO,86,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.4,-2.887,0.487,,0.696,S,A,0.64,2.38,27.704,27.704,77.62,OPA,-1.61067,0.0495842,0.00450027,0.994161 beta-lactamase_625_G39A,beta-lactamase_625_39,TEM-1,beta-lactamase_625,P62593,0.994161,NO,39,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.864,-2.728,0.864,,0.701,T,L,0.29,0.47,29.926,29.926,77.62,HOH,-1.53633,0.213352,0.00487611,0.994161 beta-lactamase_625_F149T,beta-lactamase_625_149,TEM-1,beta-lactamase_625,P62593,0.994166,NO,149,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.299,-3.669,2.37,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.213352,0.00418462,0.994166 beta-lactamase_156_G141K,beta-lactamase_156_141,TEM-1,beta-lactamase_156,P62593,0.994168,NO,141,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.828,-3.62,2.792,,0.575,T,l,0.29,-0.28,0.198,,64.69,HOO,-1.08933,0.111618,0.0012419,0.994168 beta-lactamase_39_I54P,beta-lactamase_39_54,TEM-1,beta-lactamase_39,P62593,0.994169,NO,54,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-2.838,-4.045,1.207,,0.669,E,B,0.48,-0.14,1.349,,73.78,BHH,-2.337,0.0495842,0.00403589,0.994169 beta-lactamase_156_H94T,beta-lactamase_156_94,TEM-1,beta-lactamase_156,P62593,0.994171,NO,94,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-2.5,-2.6,0.1,,0.776,,B,0.17,1.24,11.583,11.583,77.62,HBH,-1.872,0.111618,0.00389226,0.994171 beta-lactamase_2500_L196P,beta-lactamase_2500_196,TEM-1,beta-lactamase_2500,P62593,0.994174,NO,196,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-2.478,-3.165,0.687,,0.518,S,A,0.55,1.35,7.897,,77.62,AHH,-1.839,0.361275,0.00512144,0.994174 beta-lactamase_625_K254L,beta-lactamase_625_254,TEM-1,beta-lactamase_625,P62593,0.994175,NO,254,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.213352,0.00369,0.994175 beta-lactamase_156_N152V,beta-lactamase_156_152,TEM-1,beta-lactamase_156,P62593,0.994176,NO,152,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-2.757,-3.616,0.859,,0.863,H,A,0.61,0.92,4.038,,77.62,BPH,-2.97,0.111618,0.00471429,0.994176 beta-lactamase_2500_S96M,beta-lactamase_2500_96,TEM-1,beta-lactamase_2500,P62593,0.994176,NO,96,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.27,-3.49,1.22,,0.368,,b,0.27,0.39,32.348,32.348,73.78,HPP,-2.019,0.361275,0.00551835,0.994176 beta-lactamase_39_G114H,beta-lactamase_39_114,TEM-1,beta-lactamase_39,P62593,0.994177,NO,114,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.094,-4.665,3.571,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.0495842,0.00224919,0.994177 beta-lactamase_625_D161E,beta-lactamase_625_161,TEM-1,beta-lactamase_625,P62593,0.99418,NO,161,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.891,-2.299,1.408,,0.341,,A,0.75,-0.52,4.655,,61.19,HAB,-0.961333,0.213352,0.000897697,0.99418 beta-lactamase_625_S57Q,beta-lactamase_625_57,TEM-1,beta-lactamase_625,P62593,0.99418,NO,57,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.918,-3.995,2.077,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.213352,0.00492804,0.99418 Pab1_N192A,Pab1_192,Pab1,Pab1,P04147,0.994181,NO,192,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-1.079,-3.12,2.041,,0.619,T,l,,2.28,,,,HPO,-1.231,0.175299,0.000273498,0.994181 kka2_1:8_C31F,kka2_1:8_31,Kka2,kka2_1:8,P00552,0.994182,NO,31,C,F,CF,Special,Hydrophobic,5.07,3.32051,-1.74949,205,121,165,44,108.5,189.9,81.4,-2.246,-4.376,2.13,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.100394,0.00681582,0.994182 kka2_1:8_C31F,kka2_1:8_31,Kka2,kka2_1:8,P00552,0.994182,NO,31,C,F,CF,Special,Hydrophobic,5.07,3.32051,-1.74949,205,121,165,44,108.5,189.9,81.4,-2.246,-4.376,2.13,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.100394,0.00681582,0.994182 beta-lactamase_156_G234A,beta-lactamase_156_234,TEM-1,beta-lactamase_156,P62593,0.994185,NO,234,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.62,-2.853,2.233,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.111618,0.000889577,0.994185 beta-lactamase_625_W163D,beta-lactamase_625_163,TEM-1,beta-lactamase_625,P62593,0.99419,NO,163,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-1.843,-3.903,2.06,,0.467,,B,0.47,-0.5,5.019,,63.99,BHA,-1.269,0.213352,0.00418955,0.99419 hsp90_M589F,hsp90_589,hsp90,hsp90,P02829,0.994191,NO,589,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-3.858,-3.22,0,4.72723,0.032,H,A,0.84,0.31,,,,PHA,-3.24233,0.368192,0.000222939,0.994191 beta-lactamase_39_E102L,beta-lactamase_39_102,TEM-1,beta-lactamase_39,P62593,0.994192,NO,102,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.118,-3.618,1.5,,0.722,S,B,1.04,1.82,3.87,,73.08,HAH,-1.581,0.0495842,0.00486633,0.994192 beta-lactamase_0_R257M,beta-lactamase_0_257,TEM-1,beta-lactamase_0,P62593,0.994194,NO,257,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.0500837,0.00756629,0.994194 beta-lactamase_156_P143S,beta-lactamase_156_143,TEM-1,beta-lactamase_156,P62593,0.994194,NO,143,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.967,-3.441,2.474,,0.075,H,A,0.52,-0.37,0.479,,66.78,OOB,-1.354,0.111618,0.00114551,0.994194 PSD95pdz3_R312C,PSD95pdz3_312,PSD95pdz3,PSD95pdz3,P31016,0.994195,NO,312,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.582,-4.769,3.187,5.76826,,,,,12.2409,,,,OBB,-1.46667,0.0758425,0.00196255,0.994195 beta-lactamase_2500_Q97A,beta-lactamase_2500_97,TEM-1,beta-lactamase_2500,P62593,0.994196,NO,97,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.072,-2.26,0.188,,0.823,G,A,0.64,2.42,1.157,,77.62,PPP,-2.43833,0.361275,0.0045116,0.994196 beta-lactamase_39_L167D,beta-lactamase_39_167,TEM-1,beta-lactamase_39,P62593,0.994196,NO,167,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.138,-4.03,2.892,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.0495842,0.00303566,0.994196 beta-lactamase_156_A148D,beta-lactamase_156_148,TEM-1,beta-lactamase_156,P62593,0.994199,NO,148,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.757,-2.341,0.584,,0.379,H,A,0.46,-0.55,3.551,,72.73,PHH,-1.40167,0.111618,0.00547053,0.994199 kka2_1:8_P249T,kka2_1:8_249,Kka2,kka2_1:8,P00552,0.994199,NO,249,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.867,-2.639,0.772,,0.406,.,B,0.52,-0.01,1.699,,92.05,HOA,-1.66867,0.100394,0.011045,0.994199 kka2_1:8_P249T,kka2_1:8_249,Kka2,kka2_1:8,P00552,0.994199,NO,249,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.867,-2.639,0.772,,0.406,.,B,0.52,-0.01,1.699,,92.05,HOA,-1.66867,0.100394,0.011045,0.994199 beta-lactamase_156_P165S,beta-lactamase_156_165,TEM-1,beta-lactamase_156,P62593,0.994206,NO,165,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.373,-3.19,1.817,,0.203,T,A,0.52,-0.31,3.907,,73.78,AOA,-1.359,0.111618,0.00549538,0.994206 beta-lactamase_156_L89P,beta-lactamase_156_89,TEM-1,beta-lactamase_156,P62593,0.994213,NO,89,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.096,-2.221,1.125,,0.168,T,A,0.55,0.63,2.633,,64.34,PHO,-1.75767,0.111618,0.00207068,0.994213 kka2_1:4_Q136L,kka2_1:4_136,Kka2,kka2_1:4,P00552,0.994214,NO,136,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-3.021,-3.571,0.55,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.168804,0.00624149,0.994214 beta-lactamase_39_A40L,beta-lactamase_39_40,TEM-1,beta-lactamase_39,P62593,0.99422,NO,40,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.402,-3.399,1.997,,0.155,S,B,0.46,0.21,0.783,,73.78,OHB,-1.40267,0.0495842,0.00490026,0.99422 beta-lactamase_625_E169W,beta-lactamase_625_169,TEM-1,beta-lactamase_625,P62593,0.994222,NO,169,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.23,-5.379,4.149,,0.337,,A,1.04,1,1.806,,73.08,PAH,-1.16533,0.213352,0.00400994,0.994222 PSD95pdz3_D332R,PSD95pdz3_332,PSD95pdz3,PSD95pdz3,P31016,0.994223,NO,332,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.264,-3.615,2.351,6.09878,,,,,48.762,,,,AAO,-1.22533,0.0758425,0.000937818,0.994223 beta-lactamase_156_G194T,beta-lactamase_156_194,TEM-1,beta-lactamase_156,P62593,0.994224,NO,194,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.396,-2.79,1.394,,0.276,S,b,0.29,0.36,1.346,,67.83,POA,-1.832,0.111618,0.00392163,0.994224 beta-lactamase_156_H287W,beta-lactamase_156_287,TEM-1,beta-lactamase_156,P62593,0.994241,NO,287,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,,,,,,,,,,,,,BBH,-1.111,0.111618,,0.994241 beta-lactamase_156_Q88L,beta-lactamase_156_88,TEM-1,beta-lactamase_156,P62593,0.994241,NO,88,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.086,-3.504,1.418,,0.807,,B,0.64,2.03,0.911,,77.62,APH,-1.53433,0.111618,0.00504167,0.994241 beta-lactamase_156_M127E,beta-lactamase_156_127,TEM-1,beta-lactamase_156,P62593,0.994244,NO,127,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-2.251,-3.04,0.789,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.111618,0.00437927,0.994244 beta-lactamase_39_S266N,beta-lactamase_39_266,TEM-1,beta-lactamase_39,P62593,0.994245,NO,266,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.0495842,0.0140785,0.994245 beta-lactamase_625_A225G,beta-lactamase_625_225,TEM-1,beta-lactamase_625,P62593,0.994247,NO,225,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.845,-2.827,0.982,,1,T,B,0.46,-0.38,9.874,9.874,74.48,OHO,-1.39967,0.213352,0.00465057,0.994247 beta-lactamase_39_L73Y,beta-lactamase_39_73,TEM-1,beta-lactamase_39,P62593,0.994248,NO,73,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.507,-3.917,2.41,,,H,A,0.55,-0.64,2.09,,67.83,HHH,-1.487,0.0495842,0.00488983,0.994248 beta-lactamase_R202R,beta-lactamase_202,TEM-1,beta-lactamase,P62593,0.994249,NO,202,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.292,-1.292,,5.16273,0.188,H,A,0.68,0.62,1.918,,77.62,PBP,-1.54767,0.221079,0.00321899,0.994249 beta-lactamase_156_P224D,beta-lactamase_156_224,TEM-1,beta-lactamase_156,P62593,0.994251,NO,224,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.893,-3.513,2.62,,0.383,,B,0.52,-0.3,0.383,,74.48,HOH,-1.26433,0.111618,0.00189564,0.994251 beta-lactamase_156_R59A,beta-lactamase_156_59,TEM-1,beta-lactamase_156,P62593,0.994253,NO,59,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.345,-3.163,1.818,,0.329,S,L,1.2,-0.09,2.995,,73.08,HBO,-2.24267,0.111618,0.00318082,0.994253 beta-lactamase_156_N274H,beta-lactamase_156_274,TEM-1,beta-lactamase_156,P62593,0.994259,NO,274,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.111618,0.0110418,0.994259 beta-lactamase_0_L136N,beta-lactamase_0_136,TEM-1,beta-lactamase_0,P62593,0.99426,NO,136,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.232,-4.217,2.985,,,H,A,0.55,-0.34,0.648,,48.95,HHH,-1.088,0.0500837,0.00442304,0.99426 beta-lactamase_2500_E46M,beta-lactamase_2500_46,TEM-1,beta-lactamase_2500,P62593,0.994264,NO,46,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.94,-4.375,2.435,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.361275,0.00427568,0.994264 beta-lactamase_2500_L196Y,beta-lactamase_2500_196,TEM-1,beta-lactamase_2500,P62593,0.994267,NO,196,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-2.478,-4.286,1.808,,0.518,S,A,0.55,1.35,7.897,,77.62,AHH,-1.839,0.361275,0.00512144,0.994267 gb1_K230I,gb1_230,gb1,gb1,P06654,0.994267,NO,230,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.701,-3.571,1.87,,,,,,,0.166,,11.83,HBH,-1.52867,0.177985,0.00331703,0.994267 gb1_T244Y,gb1_244,gb1,gb1,P06654,0.994267,NO,244,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.637,-3.855,2.218,,,,,,,0.202,,11.83,PPA,-1.92567,0.177985,0.00222755,0.994267 beta-lactamase_625_K144E,beta-lactamase_625_144,TEM-1,beta-lactamase_625,P62593,0.994268,NO,144,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-2.388,-2.372,-0.016,,0.863,H,A,2.34,1.27,2.313,,77.62,OBA,-1.904,0.213352,0.00481141,0.994268 beta-lactamase_2500_E102T,beta-lactamase_2500_102,TEM-1,beta-lactamase_2500,P62593,0.994269,NO,102,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.118,-2.156,0.038,,0.722,S,B,1.04,1.82,1.336,,73.08,HAH,-1.581,0.361275,0.00486633,0.994269 beta-lactamase_39_R41T,beta-lactamase_39_41,TEM-1,beta-lactamase_39,P62593,0.994271,NO,41,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-0.942,-3.385,2.443,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.0495842,0.00123327,0.994271 beta-lactamase_625_H24S,beta-lactamase_625_24,TEM-1,beta-lactamase_625,P62593,0.994271,NO,24,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-2.481,-1.903,-0.578,,,,,,,2.708,,93.01,OBO,-2.0035,0.213352,0.00238894,0.994271 beta-lactamase_156_I54L,beta-lactamase_156_54,TEM-1,beta-lactamase_156,P62593,0.994274,NO,54,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-2.838,-2.471,-0.367,,0.669,E,B,0.48,-0.14,0.541,,73.78,BHH,-2.337,0.111618,0.00403589,0.994274 beta-lactamase_156_K144L,beta-lactamase_156_144,TEM-1,beta-lactamase_156,P62593,0.994277,NO,144,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-2.388,-3.577,1.189,,0.863,H,A,2.34,1.27,2.073,,77.62,OBA,-1.904,0.111618,0.00481141,0.994277 beta-lactamase_39_Q97L,beta-lactamase_39_97,TEM-1,beta-lactamase_39,P62593,0.994279,NO,97,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.072,-3.528,1.456,,0.823,G,A,0.64,2.42,4.457,,77.62,PPP,-2.43833,0.0495842,0.0045116,0.994279 beta-lactamase_625_N173R,beta-lactamase_625_173,TEM-1,beta-lactamase_625,P62593,0.994279,NO,173,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-2.663,-3.837,1.174,,1.044,T,l,0.61,1.25,1.426,,77.62,OPA,-1.46633,0.213352,0.0033769,0.994279 beta-lactamase_156_A148S,beta-lactamase_156_148,TEM-1,beta-lactamase_156,P62593,0.994282,NO,148,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.757,-2.791,1.034,,0.379,H,A,0.46,-0.55,3.551,,72.73,PHH,-1.40167,0.111618,0.00547053,0.994282 beta-lactamase_156_M66H,beta-lactamase_156_66,TEM-1,beta-lactamase_156,P62593,0.994282,NO,66,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.362,-4.866,3.504,,0.013,,A,0.55,-0.7,1.94,,73.08,OHH,-1.49567,0.111618,0.00412876,0.994282 beta-lactamase_39_K30C,beta-lactamase_39_30,TEM-1,beta-lactamase_39,P62593,0.994282,NO,30,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-2.307,-5.006,2.699,,0.142,H,A,2.34,-0.65,6.717,,93.01,HBH,-2.32833,0.0495842,0.00448593,0.994282 beta-lactamase_39_L47C,beta-lactamase_39_47,TEM-1,beta-lactamase_39,P62593,0.994286,NO,47,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.876,-5.002,3.126,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.0495842,0.00439844,0.994286 kka2_1:2_G43C,kka2_1:2_43,Kka2,kka2_1:2,P00552,0.994286,NO,43,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.587,-3.529,1.942,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.295029,0.0071925,0.994286 beta-lactamase_156_G226R,beta-lactamase_156_226,TEM-1,beta-lactamase_156,P62593,0.994288,NO,226,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.461,-3.022,1.561,,0.701,T,l,0.29,-0.25,3.199,,74.48,HOH,-1.42933,0.111618,0.00665294,0.994288 beta-lactamase_39_G76L,beta-lactamase_39_76,TEM-1,beta-lactamase_39,P62593,0.994288,NO,76,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.189,-3.521,2.332,,,H,A,0.29,-0.67,2.145,,67.83,OOH,-1.22267,0.0495842,0.00476637,0.994288 beta-lactamase_39_P250G,beta-lactamase_39_250,TEM-1,beta-lactamase_39,P62593,0.994288,NO,250,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.0495842,0.00550899,0.994288 beta-lactamase_39_T178A,beta-lactamase_39_178,TEM-1,beta-lactamase_39,P62593,0.994289,NO,178,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-0.791,-2.853,2.062,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.0495842,0.000684366,0.994289 beta-lactamase_2500_R275H,beta-lactamase_2500_275,TEM-1,beta-lactamase_2500,P62593,0.994293,NO,275,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.361275,0.0141984,0.994293 beta-lactamase_39_I45A,beta-lactamase_39_45,TEM-1,beta-lactamase_39,P62593,0.994293,NO,45,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-2.421,-2.001,-0.42,,,E,B,0.48,-0.3,2.256,,77.62,HHA,-2.30267,0.0495842,0.00452842,0.994293 beta-lactamase_Q204Q,beta-lactamase_204,TEM-1,beta-lactamase,P62593,0.994298,NO,204,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-1.382,-1.382,,5.46394,0.204,H,A,0.12,0.09,1.707,,66.08,PPH,-1.49067,0.221079,0.00364106,0.994298 beta-lactamase_156_D83R,beta-lactamase_156_83,TEM-1,beta-lactamase_156,P62593,0.994299,NO,83,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.066,-3.889,2.823,,0.354,H,A,0.75,0.22,1.281,,48.95,HAH,-1.34733,0.111618,0.00205968,0.994299 beta-lactamase_625_R189M,beta-lactamase_625_189,TEM-1,beta-lactamase_625,P62593,0.9943,NO,189,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.844,-4.718,2.874,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.213352,0.0050699,0.9943 beta-lactamase_156_R176T,beta-lactamase_156_176,TEM-1,beta-lactamase_156,P62593,0.994302,NO,176,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-0.863,-3.421,2.558,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.111618,0.00105554,0.994302 beta-lactamase_625_R63Q,beta-lactamase_625_63,TEM-1,beta-lactamase_625,P62593,0.994302,NO,63,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-0.943,-3.532,2.589,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.213352,0.00126938,0.994302 beta-lactamase_156_R63L,beta-lactamase_156_63,TEM-1,beta-lactamase_156,P62593,0.994304,NO,63,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-0.943,-2.476,1.533,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.111618,0.00126938,0.994304 beta-lactamase_39_R273C,beta-lactamase_39_273,TEM-1,beta-lactamase_39,P62593,0.994305,NO,273,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.314,-5.09,2.776,,0.564,H,A,1.2,1.57,2.163,,73.78,ABP,-1.841,0.0495842,0.0077952,0.994305 beta-lactamase_39_L197G,beta-lactamase_39_197,TEM-1,beta-lactamase_39,P62593,0.994306,NO,197,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.853,-3.681,2.828,,0.007,S,B,0.55,0.33,1.559,,60.14,HHP,-1.833,0.0495842,0.00144602,0.994306 beta-lactamase_156_E272Q,beta-lactamase_156_272,TEM-1,beta-lactamase_156,P62593,0.994309,NO,272,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.111618,0.00545371,0.994309 beta-lactamase_156_H156Q,beta-lactamase_156_156,TEM-1,beta-lactamase_156,P62593,0.994316,NO,156,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-3.156,-2.776,-0.38,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.111618,0.00468596,0.994316 beta-lactamase_156_G85M,beta-lactamase_156_85,TEM-1,beta-lactamase_156,P62593,0.994323,NO,85,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.011,-4.877,3.866,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.111618,0.00252173,0.994323 beta-lactamase_156_M127H,beta-lactamase_156_127,TEM-1,beta-lactamase_156,P62593,0.994329,NO,127,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-2.251,-4.786,2.535,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.111618,0.00437927,0.994329 kka2_1:8_L60M,kka2_1:8_60,Kka2,kka2_1:8,P00552,0.994333,NO,60,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.997,-2.995,1.998,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.100394,0.00262176,0.994333 kka2_1:8_L60M,kka2_1:8_60,Kka2,kka2_1:8,P00552,0.994333,NO,60,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.997,-2.995,1.998,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.100394,0.00262176,0.994333 beta-lactamase_156_K213C,beta-lactamase_156_213,TEM-1,beta-lactamase_156,P62593,0.994334,NO,213,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.81,-5.208,3.398,,0.67,,A,2.34,0.29,3.924,,67.83,ABH,-1.57767,0.111618,0.00610411,0.994334 beta-lactamase_625_K32N,beta-lactamase_625_32,TEM-1,beta-lactamase_625,P62593,0.994334,NO,32,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.984,-2.965,0.981,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.213352,0.00401283,0.994334 Pab1_N162D,Pab1_162,Pab1,Pab1,P04147,0.994335,NO,162,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-2.313,-3.525,1.212,,0.681,T,A,,1.12,,,,APO,-1.532,0.175299,0.0030719,0.994335 beta-lactamase_39_G226V,beta-lactamase_39_226,TEM-1,beta-lactamase_39,P62593,0.994342,NO,226,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.461,-3.807,2.346,,0.701,T,l,0.29,-0.25,23.034,23.034,74.48,HOH,-1.42933,0.0495842,0.00665294,0.994342 beta-lactamase_156_K190W,beta-lactamase_156_190,TEM-1,beta-lactamase_156,P62593,0.994348,NO,190,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.994,-5.522,3.528,,0.371,H,A,2.34,0.16,1.513,,77.62,BBH,-1.64167,0.111618,0.00574527,0.994348 beta-lactamase_0_L28T,beta-lactamase_0_28,TEM-1,beta-lactamase_0,P62593,0.994351,NO,28,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.579,-3.444,1.865,,0.277,H,A,0.55,-0.16,9.35,9.35,93.01,PHH,-2.11333,0.0500837,0.00359321,0.994351 beta-lactamase_39_T158G,beta-lactamase_39_158,TEM-1,beta-lactamase_39,P62593,0.994353,NO,158,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.116,-3.288,2.172,,0.036,,B,0.22,-0.85,2.755,,69.58,HPB,-1.269,0.0495842,0.00341825,0.994353 beta-lactamase_39_V42C,beta-lactamase_39_42,TEM-1,beta-lactamase_39,P62593,0.994356,NO,42,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.564,-4.789,3.225,,0.017,E,B,0.44,-0.51,1.86,,63.99,BHO,-1.042,0.0495842,0.00404515,0.994356 beta-lactamase_156_K144C,beta-lactamase_156_144,TEM-1,beta-lactamase_156,P62593,0.994357,NO,144,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-2.388,-5.107,2.719,,0.863,H,A,2.34,1.27,2.073,,77.62,OBA,-1.904,0.111618,0.00481141,0.994357 beta-lactamase_39_C121T,beta-lactamase_39_121,TEM-1,beta-lactamase_39,P62593,0.994373,NO,121,C,T,CT,Special,Polar,5.07,5.6,0.53,149,121,119,-2,108.5,116.1,7.6,-0.953,-3.447,2.494,,,H,A,0.46,-0.81,7.644,,63.29,HOP,-1.46767,0.0495842,0.000744322,0.994373 beta-lactamase_2500_S256G,beta-lactamase_2500_256,TEM-1,beta-lactamase_2500,P62593,0.994374,NO,256,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.361275,0.00710634,0.994374 PSD95pdz3_L342S,PSD95pdz3_342,PSD95pdz3,PSD95pdz3,P31016,0.994374,NO,342,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.347,-3.292,1.945,5.03015,,,,,12.0762,,,,HHH,-1.428,0.0758425,0.00081112,0.994374 beta-lactamase_156_Q97W,beta-lactamase_156_97,TEM-1,beta-lactamase_156,P62593,0.994375,NO,97,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.072,-5.457,3.385,,0.823,G,A,0.64,2.42,4.457,,77.62,PPP,-2.43833,0.111618,0.0045116,0.994375 beta-lactamase_625_R81E,beta-lactamase_625_81,TEM-1,beta-lactamase_625,P62593,0.994376,NO,81,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.466,-2.677,1.211,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.213352,0.00499763,0.994376 PSD95pdz3_E373D,PSD95pdz3_373,PSD95pdz3,PSD95pdz3,P31016,0.994376,NO,373,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.404,-2.475,1.071,5.79743,,,,,27.9833,,,,BAP,-1.57667,0.0758425,0.000387698,0.994376 beta-lactamase_156_G253C,beta-lactamase_156_253,TEM-1,beta-lactamase_156,P62593,0.994379,NO,253,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.111618,0.00786358,0.994379 beta-lactamase_625_V101D,beta-lactamase_625_101,TEM-1,beta-lactamase_625,P62593,0.994381,NO,101,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.295,-2.887,1.592,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.213352,0.00374492,0.994381 beta-lactamase_625_E145T,beta-lactamase_625_145,TEM-1,beta-lactamase_625,P62593,0.994385,NO,145,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.357,-3.565,1.208,,0.545,H,A,1.04,0.79,2.64,,77.62,BAH,-2.069,0.213352,0.00553285,0.994385 beta-lactamase_2500_T112P,beta-lactamase_2500_112,TEM-1,beta-lactamase_2500,P62593,0.994386,NO,112,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.186,-3.939,1.753,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.361275,0.00531334,0.994386 beta-lactamase_156_M127Q,beta-lactamase_156_127,TEM-1,beta-lactamase_156,P62593,0.99439,NO,127,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-2.251,-2.96,0.709,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.111618,0.00437927,0.99439 beta-lactamase_156_V106E,beta-lactamase_156_106,TEM-1,beta-lactamase_156,P62593,0.994391,NO,106,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.218,-3.859,2.641,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.111618,0.00304168,0.994391 beta-lactamase_625_T131M,beta-lactamase_625_131,TEM-1,beta-lactamase_625,P62593,0.994395,NO,131,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.328,-4.602,3.274,,,H,A,0.22,-0.69,2.031,,67.48,PPH,-1.00867,0.213352,0.00345886,0.994395 beta-lactamase_625_N173H,beta-lactamase_625_173,TEM-1,beta-lactamase_625,P62593,0.994396,NO,173,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-2.663,-4.635,1.972,,1.044,T,l,0.61,1.25,1.426,,77.62,OPA,-1.46633,0.213352,0.0033769,0.994396 beta-lactamase_39_A200I,beta-lactamase_39_200,TEM-1,beta-lactamase_39,P62593,0.994399,NO,200,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.878,-3.937,2.059,,0.757,H,A,0.46,-0.19,1.54,,77.62,HHP,-2.001,0.0495842,0.0060056,0.994399 beta-lactamase_625_E279Q,beta-lactamase_625_279,TEM-1,beta-lactamase_625,P62593,0.994401,NO,279,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.213352,0.0192826,0.994401 beta-lactamase_2500_N50D,beta-lactamase_2500_50,TEM-1,beta-lactamase_2500,P62593,0.994402,NO,50,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-2.979,-2.468,-0.511,,0.912,T,A,0.61,1.24,1.581,,77.62,HPP,-2.134,0.361275,0.0047211,0.994402 beta-lactamase_625_L196V,beta-lactamase_625_196,TEM-1,beta-lactamase_625,P62593,0.994404,NO,196,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-2.478,-2.258,-0.22,,0.518,S,A,0.55,1.35,12.152,12.152,77.62,AHH,-1.839,0.213352,0.00512144,0.994404 beta-lactamase_156_P250V,beta-lactamase_156_250,TEM-1,beta-lactamase_156,P62593,0.99441,NO,250,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.111618,0.00550899,0.99441 beta-lactamase_2500_N50G,beta-lactamase_2500_50,TEM-1,beta-lactamase_2500,P62593,0.994413,NO,50,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-2.979,-2.053,-0.926,,0.912,T,A,0.61,1.24,1.581,,77.62,HPP,-2.134,0.361275,0.0047211,0.994413 beta-lactamase_156_I171K,beta-lactamase_156_171,TEM-1,beta-lactamase_156,P62593,0.994417,NO,171,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-2.431,-2.528,0.097,,0.361,,B,0.48,0.53,3.869,,77.62,HHO,-1.55533,0.111618,0.00623355,0.994417 beta-lactamase_156_A124S,beta-lactamase_156_124,TEM-1,beta-lactamase_156,P62593,0.994422,NO,124,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.181,-3.066,1.885,,,H,A,0.46,-0.9,2.027,,64.34,HHH,-1.152,0.111618,0.00481399,0.994422 beta-lactamase_39_R239S,beta-lactamase_39_239,TEM-1,beta-lactamase_39,P62593,0.994423,NO,239,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.0495842,0.00213852,0.994423 beta-lactamase_156_K286E,beta-lactamase_156_286,TEM-1,beta-lactamase_156,P62593,0.994427,NO,286,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.111618,,0.994427 beta-lactamase_K144Y,beta-lactamase_144,TEM-1,beta-lactamase,P62593,0.994428,NO,144,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-2.388,-4.321,1.933,6.02507,0.863,H,A,2.81,1.27,0.515,,77.62,OBA,-1.904,0.221079,0.00481141,0.994428 beta-lactamase_156_S80F,beta-lactamase_156_80,TEM-1,beta-lactamase_156,P62593,0.994429,NO,80,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.029,-4.287,2.258,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.111618,0.00565569,0.994429 beta-lactamase_156_H156A,beta-lactamase_156_156,TEM-1,beta-lactamase_156,P62593,0.994432,NO,156,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-3.156,-2.83,-0.326,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.111618,0.00468596,0.994432 beta-lactamase_0_N50W,beta-lactamase_0_50,TEM-1,beta-lactamase_0,P62593,0.994433,NO,50,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-2.979,-5.454,2.475,,0.912,T,A,0.61,1.24,9.874,9.874,77.62,HPP,-2.134,0.0500837,0.0047211,0.994433 gb1_K230V,gb1_230,gb1,gb1,P06654,0.994434,NO,230,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.701,-3.221,1.52,,,,,,,0.166,,11.83,HBH,-1.52867,0.177985,0.00331703,0.994434 beta-lactamase_2500_A268S,beta-lactamase_2500_268,TEM-1,beta-lactamase_2500,P62593,0.994442,NO,268,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.361275,0.0102525,0.994442 beta-lactamase_625_S96F,beta-lactamase_625_96,TEM-1,beta-lactamase_625,P62593,0.994445,NO,96,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.27,-4.388,2.118,,0.368,,b,0.27,0.39,5.244,,73.78,HPP,-2.019,0.213352,0.00551835,0.994445 beta-lactamase_156_L74E,beta-lactamase_156_74,TEM-1,beta-lactamase_156,P62593,0.994449,NO,74,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.296,-3.786,2.49,,,H,A,0.55,-0.91,0.746,,50,HHO,-1.34933,0.111618,0.00493255,0.994449 Pab1_P200L,Pab1_200,Pab1,Pab1,P04147,0.994449,NO,200,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.871,-2.435,0.564,,,,,,,3.877,,80.59,HOO,-1.7005,0.175299,0.00190795,0.994449 beta-lactamase_156_K144D,beta-lactamase_156_144,TEM-1,beta-lactamase_156,P62593,0.994454,NO,144,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-2.388,-3.584,1.196,,0.863,H,A,2.34,1.27,2.073,,77.62,OBA,-1.904,0.111618,0.00481141,0.994454 beta-lactamase_39_T198I,beta-lactamase_39_198,TEM-1,beta-lactamase_39,P62593,0.994455,NO,198,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.168,-3.831,1.663,,0.489,,B,0.22,-0.13,3.614,,73.78,HPH,-1.98767,0.0495842,0.004311,0.994455 beta-lactamase_39_G240Y,beta-lactamase_39_240,TEM-1,beta-lactamase_39,P62593,0.994457,NO,240,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.0495842,0.00591201,0.994457 beta-lactamase_625_T107V,beta-lactamase_625_107,TEM-1,beta-lactamase_625,P62593,0.99446,NO,107,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.117,-3.226,2.109,,,G,A,0.22,-0.06,3.676,,67.83,HPA,-1.265,0.213352,0.00239347,0.99446 beta-lactamase_2500_T158S,beta-lactamase_2500_158,TEM-1,beta-lactamase_2500,P62593,0.994461,NO,158,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.116,-1.795,0.679,,0.036,,B,0.22,-0.85,1.344,,69.58,HPB,-1.269,0.361275,0.00341825,0.994461 beta-lactamase_156_E108Q,beta-lactamase_156_108,TEM-1,beta-lactamase_156,P62593,0.994465,NO,108,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.46,-2.893,1.433,,0.572,G,A,1.04,1.87,8.602,8.602,72.73,PAB,-1.437,0.111618,0.00413372,0.994465 beta-lactamase_39_G265A,beta-lactamase_39_265,TEM-1,beta-lactamase_39,P62593,0.994466,NO,265,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.0495842,0.00811926,0.994466 kka2_1:8_I29A,kka2_1:8_29,Kka2,kka2_1:8,P00552,0.994467,NO,29,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.692,-3.281,1.589,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.100394,0.00619521,0.994467 kka2_1:8_I29A,kka2_1:8_29,Kka2,kka2_1:8,P00552,0.994467,NO,29,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.692,-3.281,1.589,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.100394,0.00619521,0.994467 beta-lactamase_G90S,beta-lactamase_90,TEM-1,beta-lactamase,P62593,0.99447,NO,90,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-2.091,-2.198,0.107,5.51991,0.598,T,A,0.23,0.32,1.791,,77.62,HOB,-1.52633,0.221079,0.00490273,0.99447 beta-lactamase_625_A40S,beta-lactamase_625_40,TEM-1,beta-lactamase_625,P62593,0.994471,NO,40,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.402,-3.164,1.762,,0.155,S,B,0.46,0.21,1.357,,73.78,OHB,-1.40267,0.213352,0.00490026,0.994471 beta-lactamase_625_A182P,beta-lactamase_625_182,TEM-1,beta-lactamase_625,P62593,0.994474,NO,182,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.777,-3.952,2.175,,0.136,H,A,0.46,-0.66,16.784,16.784,93.01,OHH,-1.27367,0.213352,0.00559099,0.994474 beta-lactamase_39_A84G,beta-lactamase_39_84,TEM-1,beta-lactamase_39,P62593,0.994478,NO,84,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.651,-3.358,1.707,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.0495842,0.00503822,0.994478 kka2_1:8_K112T,kka2_1:8_112,Kka2,kka2_1:8,P00552,0.994483,NO,112,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-2.491,-2.629,0.138,,0.076,H,A,1.3,-1.37,10.58,10.58,56.06,ABH,-2.00133,0.100394,0.00645389,0.994483 kka2_1:8_K112T,kka2_1:8_112,Kka2,kka2_1:8,P00552,0.994483,NO,112,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-2.491,-2.629,0.138,,0.076,H,A,1.3,-1.37,10.58,10.58,56.06,ABH,-2.00133,0.100394,0.00645389,0.994483 beta-lactamase_39_L218S,beta-lactamase_39_218,TEM-1,beta-lactamase_39,P62593,0.994485,NO,218,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.391,-2.79,1.399,,,I,b,0.55,-0.53,2.038,,74.48,OHH,-1.58867,0.0495842,0.00618274,0.994485 beta-lactamase_625_R189T,beta-lactamase_625_189,TEM-1,beta-lactamase_625,P62593,0.994486,NO,189,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.844,-3.622,1.778,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.213352,0.0050699,0.994486 beta-lactamase_156_T186K,beta-lactamase_156_186,TEM-1,beta-lactamase_156,P62593,0.99449,NO,186,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.522,-2.678,0.156,,0.396,H,A,0.22,-0.28,16.606,16.606,77.62,HPP,-1.77633,0.111618,0.00485034,0.99449 beta-lactamase_T267A,beta-lactamase_267,TEM-1,beta-lactamase,P62593,0.994493,NO,267,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.308,-2.34,0.032,5.28263,0.54,,B,0.69,-0.14,0.374,,73.78,HPH,-1.9,0.221079,0.0102128,0.994493 beta-lactamase_156_L191Y,beta-lactamase_156_191,TEM-1,beta-lactamase_156,P62593,0.994494,NO,191,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.087,-3.913,2.826,,,H,A,0.55,0.09,1.372,,63.29,BHH,-1.445,0.111618,0.00263549,0.994494 beta-lactamase_156_A235G,beta-lactamase_156_235,TEM-1,beta-lactamase_156,P62593,0.994498,NO,235,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.266,-2.075,0.809,,0.32,E,B,0.46,-0.86,1.344,,50,OHO,-0.89,0.111618,0.00493474,0.994498 beta-lactamase_156_Q267W,beta-lactamase_156_267,TEM-1,beta-lactamase_156,P62593,0.994498,NO,267,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.111618,0.0102128,0.994498 beta-lactamase_39_H287K,beta-lactamase_39_287,TEM-1,beta-lactamase_39,P62593,0.994499,NO,287,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,,,,,,,,,,,,,BBH,-1.111,0.0495842,,0.994499 beta-lactamase_625_T187A,beta-lactamase_625_187,TEM-1,beta-lactamase_625,P62593,0.994499,NO,187,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.401,-3.072,1.671,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.213352,0.00491782,0.994499 beta-lactamase_625_E175R,beta-lactamase_625_175,TEM-1,beta-lactamase_625,P62593,0.994502,NO,175,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.336,-3.064,0.728,,0.551,,A,1.04,1.05,8.527,8.527,77.62,AAB,-1.31233,0.213352,0.00482205,0.994502 beta-lactamase_156_Y103C,beta-lactamase_156_103,TEM-1,beta-lactamase_156,P62593,0.994506,NO,103,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-1.33,-5.047,3.717,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.111618,0.00443048,0.994506 beta-lactamase_625_T269M,beta-lactamase_625_269,TEM-1,beta-lactamase_625,P62593,0.994523,NO,269,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.213352,0.00950944,0.994523 beta-lactamase_625_R92I,beta-lactamase_625_92,TEM-1,beta-lactamase_625,P62593,0.994524,NO,92,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.718,-3.773,2.055,,0.479,E,B,1.2,1.36,3.069,,65.38,BBH,-1.50367,0.213352,0.00429626,0.994524 Pab1_P135H,Pab1_135,Pab1,Pab1,P04147,0.994524,NO,135,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.457,-4.528,3.071,,,,,,,6.41,,81.8,BOA,-1.53367,0.175299,0.00148028,0.994524 beta-lactamase_39_N134I,beta-lactamase_39_134,TEM-1,beta-lactamase_39,P62593,0.994528,NO,134,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-0.879,-4.036,3.157,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.0495842,0.000644786,0.994528 beta-lactamase_39_Q204T,beta-lactamase_39_204,TEM-1,beta-lactamase_39,P62593,0.994528,NO,204,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-1.382,-3.549,2.167,,0.204,H,A,0.64,0.09,0.489,,66.08,PPH,-1.49067,0.0495842,0.00364106,0.994528 beta-lactamase_156_R41G,beta-lactamase_156_41,TEM-1,beta-lactamase_156,P62593,0.994536,NO,41,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-0.942,-3.321,2.379,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.111618,0.00123327,0.994536 beta-lactamase_39_R59A,beta-lactamase_39_59,TEM-1,beta-lactamase_39,P62593,0.994541,NO,59,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.345,-3.163,1.818,,0.329,S,L,1.2,-0.09,1.806,,73.08,HBO,-2.24267,0.0495842,0.00318082,0.994541 beta-lactamase_156_N134K,beta-lactamase_156_134,TEM-1,beta-lactamase_156,P62593,0.994544,NO,134,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-0.879,-2.445,1.566,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.111618,0.000644786,0.994544 beta-lactamase_39_N134G,beta-lactamase_39_134,TEM-1,beta-lactamase_39,P62593,0.994547,NO,134,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-0.879,-2.976,2.097,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.0495842,0.000644786,0.994547 beta-lactamase_39_R118M,beta-lactamase_39_118,TEM-1,beta-lactamase_39,P62593,0.994548,NO,118,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.413,-4.747,2.334,,0.457,H,A,1.2,1.39,3.961,,77.62,HBA,-1.785,0.0495842,0.00538794,0.994548 beta-lactamase_625_V101F,beta-lactamase_625_101,TEM-1,beta-lactamase_625,P62593,0.99455,NO,101,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.295,-3.936,2.641,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.213352,0.00374492,0.99455 beta-lactamase_2500_H151F,beta-lactamase_2500_151,TEM-1,beta-lactamase_2500,P62593,0.994551,NO,151,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-2.96,-4.308,1.348,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.361275,0.00216946,0.994551 beta-lactamase_39_V82C,beta-lactamase_39_82,TEM-1,beta-lactamase_39,P62593,0.994551,NO,82,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.325,-4.774,3.449,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.0495842,0.00397046,0.994551 beta-lactamase_156_R202I,beta-lactamase_156_202,TEM-1,beta-lactamase_156,P62593,0.994552,NO,202,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.292,-4.027,2.735,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.111618,0.00321899,0.994552 beta-lactamase_39_G90T,beta-lactamase_39_90,TEM-1,beta-lactamase_39,P62593,0.994559,NO,90,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-2.091,-2.913,0.822,,0.598,T,A,0.29,0.32,30.794,30.794,77.62,HOB,-1.52633,0.0495842,0.00490273,0.994559 beta-lactamase_156_N134C,beta-lactamase_156_134,TEM-1,beta-lactamase_156,P62593,0.994566,NO,134,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-0.879,-5.113,4.234,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.111618,0.000644786,0.994566 beta-lactamase_156_S256E,beta-lactamase_156_256,TEM-1,beta-lactamase_156,P62593,0.994567,NO,256,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.111618,0.00710634,0.994567 Pab1_T159S,Pab1_159,Pab1,Pab1,P04147,0.994569,NO,159,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.445,-2.968,1.523,,,,,,,2.531,,79.03,HPA,-1.19467,0.175299,0.00133849,0.994569 beta-lactamase_156_A183I,beta-lactamase_156_183,TEM-1,beta-lactamase_156,P62593,0.994578,NO,183,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.231,-2.835,1.604,,0.155,H,A,0.46,-0.91,23.859,23.859,77.62,HHH,-1.53367,0.111618,0.00296631,0.994578 beta-lactamase_156_P224Y,beta-lactamase_156_224,TEM-1,beta-lactamase_156,P62593,0.99458,NO,224,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.893,-4.387,3.494,,0.383,,B,0.52,-0.3,0.383,,74.48,HOH,-1.26433,0.111618,0.00189564,0.99458 Pab1_G163I,Pab1_163,Pab1,Pab1,P04147,0.994582,NO,163,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.809,-4.052,3.243,,0.356,B,g,,0.55,,,,POB,-1.80667,0.175299,0.00030953,0.994582 beta-lactamase_2500_L199V,beta-lactamase_2500_199,TEM-1,beta-lactamase_2500,P62593,0.994584,NO,199,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-2.942,-2.773,-0.169,,0.832,H,A,0.55,0.42,15.504,15.504,77.62,PHH,-2.32933,0.361275,0.0048649,0.994584 beta-lactamase_625_T264F,beta-lactamase_625_264,TEM-1,beta-lactamase_625,P62593,0.994589,NO,264,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.213352,0.0119399,0.994589 beta-lactamase_39_T269L,beta-lactamase_39_269,TEM-1,beta-lactamase_39,P62593,0.994592,NO,269,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.156,,,,0.646,H,A,0.53,0.4,3.889,,77.62,HPH,-1.96733,0.0495842,0.00950944,0.994592 beta-lactamase_625_M153A,beta-lactamase_625_153,TEM-1,beta-lactamase_625,P62593,0.994593,NO,153,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-3.193,-2.415,-0.778,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.213352,0.00509109,0.994593 beta-lactamase_156_G142T,beta-lactamase_156_142,TEM-1,beta-lactamase_156,P62593,0.994597,NO,142,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.707,-3.568,2.861,,0.034,,p,0.29,-0.64,0.325,,64.69,OOO,-0.834,0.111618,0.00060149,0.994597 beta-lactamase_156_N152S,beta-lactamase_156_152,TEM-1,beta-lactamase_156,P62593,0.994597,NO,152,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-2.757,-1.988,-0.769,,0.863,H,A,0.61,0.92,4.038,,77.62,BPH,-2.97,0.111618,0.00471429,0.994597 beta-lactamase_156_V214E,beta-lactamase_156_214,TEM-1,beta-lactamase_156,P62593,0.994597,NO,214,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.299,-3.704,2.405,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.111618,0.00628442,0.994597 beta-lactamase_625_D36Y,beta-lactamase_625_36,TEM-1,beta-lactamase_625,P62593,0.994598,NO,36,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.732,-3.266,0.534,,0.555,H,A,0.75,1.17,2.26,,77.62,AAP,-1.91167,0.213352,0.00476483,0.994598 beta-lactamase_625_M115A,beta-lactamase_625_115,TEM-1,beta-lactamase_625,P62593,0.994598,NO,115,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.389,-2.535,1.146,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.213352,0.0034337,0.994598 gb1_K276C,gb1_276,gb1,gb1,P06654,0.9946,NO,276,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.456,-4.927,3.471,,,,,,,0.236,,12.72,PBP,-1.65133,0.177985,0.00620493,0.9946 beta-lactamase_625_L120M,beta-lactamase_625_120,TEM-1,beta-lactamase_625,P62593,0.994608,NO,120,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.044,-4.046,3.002,,,H,A,0.55,-1.13,7.813,,64.69,AHO,-1.13633,0.213352,0.00143563,0.994608 kka2_1:4_G151T,kka2_1:4_151,Kka2,kka2_1:4,P00552,0.994612,NO,151,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.873,-3.611,2.738,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.168804,0.00339918,0.994612 beta-lactamase_625_A225K,beta-lactamase_625_225,TEM-1,beta-lactamase_625,P62593,0.994627,NO,225,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.845,-2.558,0.713,,1,T,B,0.46,-0.38,9.874,9.874,74.48,OHO,-1.39967,0.213352,0.00465057,0.994627 beta-lactamase_Q86Y,beta-lactamase_86,TEM-1,beta-lactamase,P62593,0.994634,NO,86,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.4,-4.372,1.972,5.39897,0.696,S,A,0.12,2.38,2.105,,77.62,OPA,-1.61067,0.221079,0.00450027,0.994634 beta-lactamase_39_G39W,beta-lactamase_39_39,TEM-1,beta-lactamase_39,P62593,0.994637,NO,39,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.864,-5.517,3.653,,0.701,T,L,0.29,0.47,1.454,,77.62,HOH,-1.53633,0.0495842,0.00487611,0.994637 beta-lactamase_156_E62C,beta-lactamase_156_62,TEM-1,beta-lactamase_156,P62593,0.994639,NO,62,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.193,-5.228,4.035,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.111618,0.00264802,0.994639 beta-lactamase_625_S201K,beta-lactamase_625_201,TEM-1,beta-lactamase_625,P62593,0.99464,NO,201,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.183,-3.387,2.204,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.213352,0.00198815,0.99464 beta-lactamase_625_V157W,beta-lactamase_625_157,TEM-1,beta-lactamase_625,P62593,0.994641,NO,157,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.751,-5.264,3.513,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.213352,0.00506849,0.994641 beta-lactamase_625_P165M,beta-lactamase_625_165,TEM-1,beta-lactamase_625,P62593,0.994642,NO,165,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.373,-4.649,3.276,,0.203,T,A,0.52,-0.31,0.414,,73.78,AOA,-1.359,0.213352,0.00549538,0.994642 beta-lactamase_156_N274E,beta-lactamase_156_274,TEM-1,beta-lactamase_156,P62593,0.994645,NO,274,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.111618,0.0110418,0.994645 beta-lactamase_39_G240K,beta-lactamase_39_240,TEM-1,beta-lactamase_39,P62593,0.994645,NO,240,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.0495842,0.00591201,0.994645 beta-lactamase_625_H156C,beta-lactamase_625_156,TEM-1,beta-lactamase_625,P62593,0.994646,NO,156,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-3.156,-5.208,2.052,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.213352,0.00468596,0.994646 beta-lactamase_0_L196W,beta-lactamase_0_196,TEM-1,beta-lactamase_0,P62593,0.994647,NO,196,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-2.478,-5.492,3.014,,0.518,S,A,0.55,1.35,6.513,6.513,77.62,AHH,-1.839,0.0500837,0.00512144,0.994647 beta-lactamase_39_L135T,beta-lactamase_39_135,TEM-1,beta-lactamase_39,P62593,0.994647,NO,135,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.002,-3.475,2.473,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.0495842,0.00244423,0.994647 beta-lactamase_39_D99R,beta-lactamase_39_99,TEM-1,beta-lactamase_39,P62593,0.99465,NO,99,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.191,-3.828,2.637,,0.402,G,A,0.75,0.36,0.374,,64.69,PAH,-1.794,0.0495842,0.00305446,0.99465 beta-lactamase_39_Q88G,beta-lactamase_39_88,TEM-1,beta-lactamase_39,P62593,0.994654,NO,88,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.086,-3.448,1.362,,0.807,,B,0.64,2.03,11.108,11.108,77.62,APH,-1.53433,0.0495842,0.00504167,0.994654 beta-lactamase_39_T198M,beta-lactamase_39_198,TEM-1,beta-lactamase_39,P62593,0.994655,NO,198,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.168,-4.608,2.44,,0.489,,B,0.22,-0.13,3.614,,73.78,HPH,-1.98767,0.0495842,0.004311,0.994655 beta-lactamase_625_L284V,beta-lactamase_625_284,TEM-1,beta-lactamase_625,P62593,0.994656,NO,284,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.213352,0.0686156,0.994656 beta-lactamase_0_F228V,beta-lactamase_0_228,TEM-1,beta-lactamase_0,P62593,0.994657,NO,228,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-2.342,-2.889,0.547,,0.154,E,B,0.58,-0.42,15.504,15.504,63.29,HHH,-1.53033,0.0500837,0.0046669,0.994657 beta-lactamase_2500_N152Q,beta-lactamase_2500_152,TEM-1,beta-lactamase_2500,P62593,0.994659,NO,152,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-2.757,-2.534,-0.223,,0.863,H,A,0.61,0.92,2.061,,77.62,BPH,-2.97,0.361275,0.00471429,0.994659 beta-lactamase_39_N98S,beta-lactamase_39_98,TEM-1,beta-lactamase_39,P62593,0.99466,NO,98,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-2.973,-2.34,-0.633,,0.963,G,A,0.61,1.35,14.853,14.853,77.62,PPA,-2.07867,0.0495842,0.00505389,0.99466 beta-lactamase_625_G226K,beta-lactamase_625_226,TEM-1,beta-lactamase_625,P62593,0.99466,NO,226,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.461,-2.859,1.398,,0.701,T,l,0.29,-0.25,3.199,,74.48,HOH,-1.42933,0.213352,0.00665294,0.99466 beta-lactamase_39_H156T,beta-lactamase_39_156,TEM-1,beta-lactamase_39,P62593,0.994665,NO,156,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-3.156,-2.632,-0.524,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.0495842,0.00468596,0.994665 beta-lactamase_625_H94C,beta-lactamase_625_94,TEM-1,beta-lactamase_625,P62593,0.994668,NO,94,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-2.5,-5.143,2.643,,0.776,,B,0.17,1.24,19.42,19.42,77.62,HBH,-1.872,0.213352,0.00389226,0.994668 beta-lactamase_39_S201K,beta-lactamase_39_201,TEM-1,beta-lactamase_39,P62593,0.994672,NO,201,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.183,-3.387,2.204,,0.064,H,A,0.27,-0.07,3.54,,64.69,HPB,-1.451,0.0495842,0.00198815,0.994672 beta-lactamase_Y95Y,beta-lactamase_95,TEM-1,beta-lactamase,P62593,0.994672,NO,95,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-1.715,-1.715,,5.67068,0.122,,b,0.96,-0.37,2.341,,77.62,BHP,-2.16167,0.221079,0.00479449,0.994672 beta-lactamase_156_A225G,beta-lactamase_156_225,TEM-1,beta-lactamase_156,P62593,0.994674,NO,225,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.845,-2.827,0.982,,1,T,B,0.46,-0.38,11.722,11.722,74.48,OHO,-1.39967,0.111618,0.00465057,0.994674 beta-lactamase_156_G281A,beta-lactamase_156_281,TEM-1,beta-lactamase_156,P62593,0.994681,NO,281,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.111618,0.0406482,0.994681 beta-lactamase_625_G142N,beta-lactamase_625_142,TEM-1,beta-lactamase_625,P62593,0.994681,NO,142,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.707,-3.445,2.738,,0.034,,p,0.29,-0.64,1.35,,64.69,OOO,-0.834,0.213352,0.00060149,0.994681 beta-lactamase_0_G226D,beta-lactamase_0_226,TEM-1,beta-lactamase_0,P62593,0.994688,NO,226,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.461,-1.914,0.453,,0.701,T,l,0.29,-0.25,23.034,23.034,74.48,HOH,-1.42933,0.0500837,0.00665294,0.994688 beta-lactamase_156_T269S,beta-lactamase_156_269,TEM-1,beta-lactamase_156,P62593,0.994689,NO,269,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.111618,0.00950944,0.994689 kka2_1:2_N200D,kka2_1:2_200,Kka2,kka2_1:2,P00552,0.99469,NO,200,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-2.446,-2.235,-0.211,,0.756,T,L,0.61,-0.08,2.836,,64.39,APO,-2.08,0.295029,0.00838549,0.99469 beta-lactamase_625_G90T,beta-lactamase_625_90,TEM-1,beta-lactamase_625,P62593,0.994705,NO,90,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-2.091,-2.913,0.822,,0.598,T,A,0.29,0.32,0.319,,77.62,HOB,-1.52633,0.213352,0.00490273,0.994705 beta-lactamase_0_E279S,beta-lactamase_0_279,TEM-1,beta-lactamase_0,P62593,0.994706,NO,279,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.0500837,0.0192826,0.994706 beta-lactamase_39_L136M,beta-lactamase_39_136,TEM-1,beta-lactamase_39,P62593,0.994706,NO,136,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.232,-2.988,1.756,,,H,A,0.55,-0.34,0.336,,48.95,HHH,-1.088,0.0495842,0.00442304,0.994706 beta-lactamase_625_A77N,beta-lactamase_625_77,TEM-1,beta-lactamase_625,P62593,0.994706,NO,77,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.234,-3.844,2.61,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.213352,0.00282362,0.994706 beta-lactamase_39_L199K,beta-lactamase_39_199,TEM-1,beta-lactamase_39,P62593,0.994708,NO,199,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-2.942,-2.994,0.052,,0.832,H,A,0.55,0.42,15.504,15.504,77.62,PHH,-2.32933,0.0495842,0.0048649,0.994708 beta-lactamase_39_W163T,beta-lactamase_39_163,TEM-1,beta-lactamase_39,P62593,0.994708,NO,163,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-1.843,-2.765,0.922,,0.467,,B,0.47,-0.5,15.095,15.095,63.99,BHA,-1.269,0.0495842,0.00418955,0.994708 beta-lactamase_156_N50C,beta-lactamase_156_50,TEM-1,beta-lactamase_156,P62593,0.994711,NO,50,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-2.979,-5.044,2.065,,0.912,T,A,0.61,1.24,13.295,13.295,77.62,HPP,-2.134,0.111618,0.0047211,0.994711 beta-lactamase_625_P255Q,beta-lactamase_625_255,TEM-1,beta-lactamase_625,P62593,0.994715,NO,255,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.213352,0.00499612,0.994715 beta-lactamase_39_K286G,beta-lactamase_39_286,TEM-1,beta-lactamase_39,P62593,0.994716,NO,286,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.0495842,,0.994716 beta-lactamase_2500_N50E,beta-lactamase_2500_50,TEM-1,beta-lactamase_2500,P62593,0.994717,NO,50,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-2.979,-2.315,-0.664,,0.912,T,A,0.61,1.24,1.581,,77.62,HPP,-2.134,0.361275,0.0047211,0.994717 beta-lactamase_39_V260G,beta-lactamase_39_260,TEM-1,beta-lactamase_39,P62593,0.994719,NO,260,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.0495842,0.00471757,0.994719 PSD95pdz3_N369C,PSD95pdz3_369,PSD95pdz3,PSD95pdz3,P31016,0.99472,NO,369,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-1.572,-4.659,3.087,5.91569,,,,,24.1262,0.44,,87.71,BPH,-1.487,0.0758425,0.000608412,0.99472 beta-lactamase_625_A200I,beta-lactamase_625_200,TEM-1,beta-lactamase_625,P62593,0.994723,NO,200,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.878,-3.937,2.059,,0.757,H,A,0.46,-0.19,12.672,12.672,77.62,HHP,-2.001,0.213352,0.0060056,0.994723 beta-lactamase_2500_S122Y,beta-lactamase_2500_122,TEM-1,beta-lactamase_2500,P62593,0.994729,NO,122,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.406,-4.156,1.75,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.361275,0.00497825,0.994729 beta-lactamase_39_P181I,beta-lactamase_39_181,TEM-1,beta-lactamase_39,P62593,0.994735,NO,181,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.813,-3.974,3.161,,,H,A,0.52,-1.14,1.946,,61.54,HOH,-1.795,0.0495842,0.000703122,0.994735 beta-lactamase_156_H287G,beta-lactamase_156_287,TEM-1,beta-lactamase_156,P62593,0.994736,NO,287,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,,,,,,,,,,,,,BBH,-1.111,0.111618,,0.994736 beta-lactamase_0_M270I,beta-lactamase_0_270,TEM-1,beta-lactamase_0,P62593,0.994739,NO,270,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.0500837,0.00767762,0.994739 beta-lactamase_39_E145N,beta-lactamase_39_145,TEM-1,beta-lactamase_39,P62593,0.994741,NO,145,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.357,-3.655,1.298,,0.545,H,A,1.04,0.79,1.199,,77.62,BAH,-2.069,0.0495842,0.00553285,0.994741 beta-lactamase_625_A124S,beta-lactamase_625_124,TEM-1,beta-lactamase_625,P62593,0.994742,NO,124,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.181,-3.066,1.885,,,H,A,0.46,-0.9,2.027,,64.34,HHH,-1.152,0.213352,0.00481399,0.994742 beta-lactamase_156_T27D,beta-lactamase_156_27,TEM-1,beta-lactamase_156,P62593,0.994743,NO,27,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.905,-3.5,1.595,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.111618,0.00306559,0.994743 Pab1_L190E,Pab1_190,Pab1,Pab1,P04147,0.994743,NO,190,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.325,-3.607,2.282,,0.489,E,B,,2.59,,,,HHH,-1.31033,0.175299,0.00132347,0.994743 beta-lactamase_156_G43A,beta-lactamase_156_43,TEM-1,beta-lactamase_156,P62593,0.994748,NO,43,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.62,-2.853,2.233,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.111618,0.00120151,0.994748 beta-lactamase_T198N,beta-lactamase_198,TEM-1,beta-lactamase,P62593,0.994748,NO,198,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.168,-3.569,1.401,4.9209,0.489,,B,0.69,-0.13,0.37,,73.78,HPH,-1.98767,0.221079,0.004311,0.994748 beta-lactamase_156_N50G,beta-lactamase_156_50,TEM-1,beta-lactamase_156,P62593,0.994749,NO,50,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-2.979,-2.053,-0.926,,0.912,T,A,0.61,1.24,13.295,13.295,77.62,HPP,-2.134,0.111618,0.0047211,0.994749 beta-lactamase_625_L55W,beta-lactamase_625_55,TEM-1,beta-lactamase_625,P62593,0.994753,NO,55,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.86,-2.099,0.239,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.213352,0.00403741,0.994753 beta-lactamase_625_L199A,beta-lactamase_625_199,TEM-1,beta-lactamase_625,P62593,0.994754,NO,199,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-2.942,-2.055,-0.887,,0.832,H,A,0.55,0.42,1.552,,77.62,PHH,-2.32933,0.213352,0.0048649,0.994754 PSD95pdz3_G364V,PSD95pdz3_364,PSD95pdz3,PSD95pdz3,P31016,0.994754,NO,364,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.008,-3.435,2.427,5.53299,,,,,21.28,,,,POH,-1.33667,0.0758425,0.00050942,0.994754 beta-lactamase_156_T187A,beta-lactamase_156_187,TEM-1,beta-lactamase_156,P62593,0.994755,NO,187,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.401,-3.072,1.671,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.111618,0.00491782,0.994755 beta-lactamase_156_K286T,beta-lactamase_156_286,TEM-1,beta-lactamase_156,P62593,0.994756,NO,286,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.111618,,0.994756 beta-lactamase_625_A222S,beta-lactamase_625_222,TEM-1,beta-lactamase_625,P62593,0.994758,NO,222,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.103,-2.253,0.15,,0.233,H,A,0.46,-0.25,1.448,,77.62,PHH,-1.63733,0.213352,0.00466094,0.994758 beta-lactamase_2500_A268V,beta-lactamase_2500_268,TEM-1,beta-lactamase_2500,P62593,0.994762,NO,268,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.361275,0.0102525,0.994762 beta-lactamase_625_A170T,beta-lactamase_625_170,TEM-1,beta-lactamase_625,P62593,0.994762,NO,170,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.237,-3.423,2.186,,0.126,,L,0.46,-0.35,3.626,,64.69,AHH,-1.63267,0.213352,0.00431903,0.994762 beta-lactamase_39_R92I,beta-lactamase_39_92,TEM-1,beta-lactamase_39,P62593,0.994767,NO,92,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.718,-3.773,2.055,,0.479,E,B,1.2,1.36,0.389,,65.38,BBH,-1.50367,0.0495842,0.00429626,0.994767 gb1_E241L,gb1_241,gb1,gb1,P06654,0.994767,NO,241,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.672,-3.144,1.472,,,,,,,0.344,,11.83,OAP,-1.27933,0.177985,0.00250604,0.994767 gb1_V255G,gb1_255,gb1,gb1,P06654,0.994767,NO,255,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-3.127,-3.189,0.062,,,,,,,1.323,,45.54,BHH,-2.03867,0.177985,0.00408354,0.994767 beta-lactamase_625_K30F,beta-lactamase_625_30,TEM-1,beta-lactamase_625,P62593,0.994771,NO,30,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-2.307,-4.338,2.031,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.213352,0.00448593,0.994771 beta-lactamase_39_N168Q,beta-lactamase_39_168,TEM-1,beta-lactamase_39,P62593,0.994774,NO,168,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-1.029,-3.749,2.72,,0.113,G,A,0.61,-0.4,0.822,,44.41,HPA,-1.13233,0.0495842,0.00288667,0.994774 beta-lactamase_156_T139M,beta-lactamase_156_139,TEM-1,beta-lactamase_156,P62593,0.994783,NO,139,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.901,-4.659,2.758,,0.216,H,A,0.22,0.39,16.34,16.34,77.62,PPH,-2.04667,0.111618,0.00441837,0.994783 beta-lactamase_A200K,beta-lactamase_200,TEM-1,beta-lactamase,P62593,0.994792,NO,200,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.878,-2.669,0.791,5.19406,0.757,H,A,0.47,-0.19,0.436,,77.62,HHP,-2.001,0.221079,0.0060056,0.994792 beta-lactamase_D36D,beta-lactamase_36,TEM-1,beta-lactamase,P62593,0.994792,NO,36,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.732,-2.732,,5.39764,0.555,H,A,0.11,1.17,13.689,13.689,77.62,AAP,-1.91167,0.221079,0.00476483,0.994792 beta-lactamase_W163V,beta-lactamase_163,TEM-1,beta-lactamase,P62593,0.994792,NO,163,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-1.843,-3.617,1.774,6.2765,0.467,,B,1.22,-0.5,3.642,,63.99,BHA,-1.269,0.221079,0.00418955,0.994792 beta-lactamase_156_T198W,beta-lactamase_156_198,TEM-1,beta-lactamase_156,P62593,0.994795,NO,198,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.168,-5.419,3.251,,0.489,,B,0.22,-0.13,10.771,10.771,73.78,HPH,-1.98767,0.111618,0.004311,0.994795 beta-lactamase_2500_L167C,beta-lactamase_2500_167,TEM-1,beta-lactamase_2500,P62593,0.994798,NO,167,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.138,-4.763,3.625,,0.015,G,A,0.55,-0.63,7.813,,64.69,AHP,-1.30767,0.361275,0.00303566,0.994798 beta-lactamase_625_N50F,beta-lactamase_625_50,TEM-1,beta-lactamase_625,P62593,0.994798,NO,50,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-2.979,-4.333,1.354,,0.912,T,A,0.61,1.24,3.446,,77.62,HPP,-2.134,0.213352,0.0047211,0.994798 beta-lactamase_2500_L196N,beta-lactamase_2500_196,TEM-1,beta-lactamase_2500,P62593,0.994799,NO,196,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-2.478,-3.953,1.475,,0.518,S,A,0.55,1.35,7.897,,77.62,AHH,-1.839,0.361275,0.00512144,0.994799 beta-lactamase_2500_E279I,beta-lactamase_2500_279,TEM-1,beta-lactamase_2500,P62593,0.9948,NO,279,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.361275,0.0192826,0.9948 beta-lactamase_625_S104A,beta-lactamase_625_104,TEM-1,beta-lactamase_625,P62593,0.994803,NO,104,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.015,-2.043,1.028,,0.04,,b,0.27,0.57,1.76,,63.29,HPO,-1.05267,0.213352,0.00218083,0.994803 beta-lactamase_625_G226S,beta-lactamase_625_226,TEM-1,beta-lactamase_625,P62593,0.994808,NO,226,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.461,-2.74,1.279,,0.701,T,l,0.29,-0.25,3.199,,74.48,HOH,-1.42933,0.213352,0.00665294,0.994808 beta-lactamase_156_E145H,beta-lactamase_156_145,TEM-1,beta-lactamase_156,P62593,0.994816,NO,145,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.357,-4.656,2.299,,0.545,H,A,1.04,0.79,3.661,,77.62,BAH,-2.069,0.111618,0.00553285,0.994816 beta-lactamase_156_P224R,beta-lactamase_156_224,TEM-1,beta-lactamase_156,P62593,0.994819,NO,224,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.893,-2.763,1.87,,0.383,,B,0.52,-0.3,0.383,,74.48,HOH,-1.26433,0.111618,0.00189564,0.994819 beta-lactamase_2500_D271A,beta-lactamase_2500_271,TEM-1,beta-lactamase_2500,P62593,0.99482,NO,271,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.361275,0.00752082,0.99482 beta-lactamase_39_P224T,beta-lactamase_39_224,TEM-1,beta-lactamase_39,P62593,0.994824,NO,224,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.893,-3.414,2.521,,0.383,,B,0.52,-0.3,3.169,,74.48,HOH,-1.26433,0.0495842,0.00189564,0.994824 beta-lactamase_156_Q267R,beta-lactamase_156_267,TEM-1,beta-lactamase_156,P62593,0.994825,NO,267,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.111618,0.0102128,0.994825 beta-lactamase_625_T198R,beta-lactamase_625_198,TEM-1,beta-lactamase_625,P62593,0.994825,NO,198,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.168,-3.752,1.584,,0.489,,B,0.22,-0.13,0.37,,73.78,HPH,-1.98767,0.213352,0.004311,0.994825 beta-lactamase_2500_A200V,beta-lactamase_2500_200,TEM-1,beta-lactamase_2500,P62593,0.994827,NO,200,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.878,-2.943,1.065,,0.757,H,A,0.46,-0.19,0.436,,77.62,HHP,-2.001,0.361275,0.0060056,0.994827 beta-lactamase_156_T147P,beta-lactamase_156_147,TEM-1,beta-lactamase_156,P62593,0.994831,NO,147,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.149,-3.818,2.669,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.111618,0.00226017,0.994831 beta-lactamase_2500_E272L,beta-lactamase_2500_272,TEM-1,beta-lactamase_2500,P62593,0.994832,NO,272,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.361275,0.00545371,0.994832 beta-lactamase_625_G194T,beta-lactamase_625_194,TEM-1,beta-lactamase_625,P62593,0.994833,NO,194,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.396,-2.79,1.394,,0.276,S,b,0.29,0.36,3.593,,67.83,POA,-1.832,0.213352,0.00392163,0.994833 beta-lactamase_2500_K32I,beta-lactamase_2500_32,TEM-1,beta-lactamase_2500,P62593,0.994836,NO,32,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.984,-2.835,0.851,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.361275,0.00401283,0.994836 beta-lactamase_2500_K53E,beta-lactamase_2500_53,TEM-1,beta-lactamase_2500,P62593,0.994838,NO,53,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-2.313,-2.655,0.342,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.361275,0.00383383,0.994838 beta-lactamase_39_A148N,beta-lactamase_39_148,TEM-1,beta-lactamase_39,P62593,0.994839,NO,148,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.757,-3.701,1.944,,0.379,H,A,0.46,-0.55,3.551,,72.73,PHH,-1.40167,0.0495842,0.00547053,0.994839 beta-lactamase_2500_I54T,beta-lactamase_2500_54,TEM-1,beta-lactamase_2500,P62593,0.994841,NO,54,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-2.838,-2.043,-0.795,,0.669,E,B,0.48,-0.14,3.946,,73.78,BHH,-2.337,0.361275,0.00403589,0.994841 beta-lactamase_39_R63H,beta-lactamase_39_63,TEM-1,beta-lactamase_39,P62593,0.994842,NO,63,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-0.943,-4.313,3.37,,0.218,,B,1.2,-0.31,0.326,,44.06,ABH,-0.992333,0.0495842,0.00126938,0.994842 beta-lactamase_2500_E61W,beta-lactamase_2500_61,TEM-1,beta-lactamase_2500,P62593,0.99485,NO,61,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.115,-5.544,3.429,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.361275,0.00440955,0.99485 beta-lactamase_156_V42W,beta-lactamase_156_42,TEM-1,beta-lactamase_156,P62593,0.994852,NO,42,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.564,-5.336,3.772,,0.017,E,B,0.44,-0.51,2.576,,63.99,BHO,-1.042,0.111618,0.00404515,0.994852 beta-lactamase_156_L284T,beta-lactamase_156_284,TEM-1,beta-lactamase_156,P62593,0.994854,NO,284,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.111618,0.0686156,0.994854 beta-lactamase_156_Q204C,beta-lactamase_156_204,TEM-1,beta-lactamase_156,P62593,0.994865,NO,204,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-1.382,-5.114,3.732,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.111618,0.00364106,0.994865 Pab1_S147N,Pab1_147,Pab1,Pab1,P04147,0.99487,NO,147,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.267,-3.144,1.877,,0.336,H,A,,0.56,,,,HPH,-1.43033,0.175299,0.000610856,0.99487 beta-lactamase_156_Q203K,beta-lactamase_156_203,TEM-1,beta-lactamase_156,P62593,0.994872,NO,203,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.168,-2.642,0.474,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.111618,0.00631514,0.994872 kka2_1:4_T85R,kka2_1:4_85,Kka2,kka2_1:4,P00552,0.994876,NO,85,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.165,-2.814,0.649,,0.576,E,B,0.22,1.39,1.853,,71.59,HPA,-2.10133,0.168804,0.00634493,0.994876 beta-lactamase_156_L135H,beta-lactamase_156_135,TEM-1,beta-lactamase_156,P62593,0.994877,NO,135,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.002,-4.934,3.932,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.111618,0.00244423,0.994877 beta-lactamase_39_I229A,beta-lactamase_39_229,TEM-1,beta-lactamase_39,P62593,0.994882,NO,229,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.267,-3.077,1.81,,0.083,E,B,0.48,-0.76,1.114,,50,HHH,-1.58767,0.0495842,0.00477249,0.994882 beta-lactamase_39_H24R,beta-lactamase_39_24,TEM-1,beta-lactamase_39,P62593,0.994884,NO,24,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-2.481,-3.749,1.268,,,,,,,2.708,,93.01,OBO,-2.0035,0.0495842,0.00238894,0.994884 beta-lactamase_39_L136V,beta-lactamase_39_136,TEM-1,beta-lactamase_39,P62593,0.994888,NO,136,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.232,-1.932,0.7,,,H,A,0.55,-0.34,0.336,,48.95,HHH,-1.088,0.0495842,0.00442304,0.994888 beta-lactamase_39_L135N,beta-lactamase_39_135,TEM-1,beta-lactamase_39,P62593,0.994894,NO,135,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.002,-4.152,3.15,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.0495842,0.00244423,0.994894 beta-lactamase_2500_R189A,beta-lactamase_2500_189,TEM-1,beta-lactamase_2500,P62593,0.994901,NO,189,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.844,-2.739,0.895,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.361275,0.0050699,0.994901 kka2_1:8_L260C,kka2_1:8_260,Kka2,kka2_1:8,P00552,0.994901,NO,260,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.741,-4.665,3.924,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.100394,0.0233782,0.994901 kka2_1:8_L260C,kka2_1:8_260,Kka2,kka2_1:8,P00552,0.994901,NO,260,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.741,-4.665,3.924,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.100394,0.0233782,0.994901 beta-lactamase_2500_S80L,beta-lactamase_2500_80,TEM-1,beta-lactamase_2500,P62593,0.994905,NO,80,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.029,-2.857,0.828,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.361275,0.00565569,0.994905 beta-lactamase_625_T264M,beta-lactamase_625_264,TEM-1,beta-lactamase_625,P62593,0.994908,NO,264,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.213352,0.0119399,0.994908 beta-lactamase_625_R239G,beta-lactamase_625_239,TEM-1,beta-lactamase_625,P62593,0.99491,NO,239,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-0.819,-3.876,3.057,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.213352,0.00213852,0.99491 Pab1_K180V,Pab1_180,Pab1,Pab1,P04147,0.994911,NO,180,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.945,-2.707,0.762,,,,,,,,,,HBA,-1.575,0.175299,0.00295933,0.994911 kka2_1:8_A65E,kka2_1:8_65,Kka2,kka2_1:8,P00552,0.994917,NO,65,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.744,-2.135,0.391,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.100394,0.00709258,0.994917 kka2_1:8_A65E,kka2_1:8_65,Kka2,kka2_1:8,P00552,0.994917,NO,65,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.744,-2.135,0.391,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.100394,0.00709258,0.994917 Pab1_D160H,Pab1_160,Pab1,Pab1,P04147,0.994917,NO,160,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.985,-4.272,3.287,,0.396,B,B,,1.12,,,,PAA,-1.30133,0.175299,0.000311977,0.994917 beta-lactamase_0_C75T,beta-lactamase_0_75,TEM-1,beta-lactamase_0,P62593,0.994918,NO,75,C,T,CT,Special,Polar,5.07,5.6,0.53,149,121,119,-2,108.5,116.1,7.6,-1.245,-3.423,2.178,,,H,A,0.46,-0.87,2.256,,50,HOO,-1.24333,0.0500837,0.0034616,0.994918 beta-lactamase_39_T264E,beta-lactamase_39_264,TEM-1,beta-lactamase_39,P62593,0.994926,NO,264,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.0495842,0.0119399,0.994926 beta-lactamase_39_N173L,beta-lactamase_39_173,TEM-1,beta-lactamase_39,P62593,0.994931,NO,173,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-2.663,-3.749,1.086,,1.044,T,l,0.61,1.25,1.426,,77.62,OPA,-1.46633,0.0495842,0.0033769,0.994931 beta-lactamase_39_N168A,beta-lactamase_39_168,TEM-1,beta-lactamase_39,P62593,0.994937,NO,168,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-1.029,-3.17,2.141,,0.113,G,A,0.61,-0.4,0.822,,44.41,HPA,-1.13233,0.0495842,0.00288667,0.994937 PSD95pdz3_D366L,PSD95pdz3_366,PSD95pdz3,PSD95pdz3,P31016,0.994939,NO,366,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.264,-3.49,2.226,5.55684,,,,,20.2375,,,,HAH,-1.401,0.0758425,0.000481272,0.994939 beta-lactamase_625_A211W,beta-lactamase_625_211,TEM-1,beta-lactamase_625,P62593,0.99494,NO,211,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.896,-5.506,3.61,,0.369,T,A,0.46,-0.69,2.061,,77.62,AHA,-1.94633,0.213352,0.00648183,0.99494 beta-lactamase_2500_R275T,beta-lactamase_2500_275,TEM-1,beta-lactamase_2500,P62593,0.994946,NO,275,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.361275,0.0141984,0.994946 beta-lactamase_T126S,beta-lactamase_126,TEM-1,beta-lactamase,P62593,0.994951,NO,126,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.122,-2.464,1.342,4.82694,0.05,H,A,0.3,-0.05,1.14,,44.41,HPH,-1.60467,0.221079,0.00244552,0.994951 beta-lactamase_156_R118M,beta-lactamase_156_118,TEM-1,beta-lactamase_156,P62593,0.994958,NO,118,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.413,-4.747,2.334,,0.457,H,A,1.2,1.39,2.231,,77.62,HBA,-1.785,0.111618,0.00538794,0.994958 beta-lactamase_625_A77K,beta-lactamase_625_77,TEM-1,beta-lactamase_625,P62593,0.99496,NO,77,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.234,-3.628,2.394,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.213352,0.00282362,0.99496 beta-lactamase_625_P172W,beta-lactamase_625_172,TEM-1,beta-lactamase_625,P62593,0.994961,NO,172,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.998,-5.528,4.53,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.213352,0.00312594,0.994961 beta-lactamase_625_E175V,beta-lactamase_625_175,TEM-1,beta-lactamase_625,P62593,0.994965,NO,175,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.336,-2.38,0.044,,0.551,,A,1.04,1.05,8.527,8.527,77.62,AAB,-1.31233,0.213352,0.00482205,0.994965 beta-lactamase_625_S221W,beta-lactamase_625_221,TEM-1,beta-lactamase_625,P62593,0.994965,NO,221,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.754,-5.418,3.664,,0.624,H,A,0.27,-0.2,1.495,,74.48,BPH,-1.59967,0.213352,0.0046094,0.994965 beta-lactamase_156_H94F,beta-lactamase_156_94,TEM-1,beta-lactamase_156,P62593,0.994966,NO,94,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-2.5,-4.323,1.823,,0.776,,B,0.17,1.24,11.583,11.583,77.62,HBH,-1.872,0.111618,0.00389226,0.994966 beta-lactamase_625_T187I,beta-lactamase_625_187,TEM-1,beta-lactamase_625,P62593,0.994968,NO,187,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.401,-2.871,1.47,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.213352,0.00491782,0.994968 beta-lactamase_625_A222Y,beta-lactamase_625_222,TEM-1,beta-lactamase_625,P62593,0.994979,NO,222,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.103,-4.186,2.083,,0.233,H,A,0.46,-0.25,1.448,,77.62,PHH,-1.63733,0.213352,0.00466094,0.994979 beta-lactamase_2500_D36Q,beta-lactamase_2500_36,TEM-1,beta-lactamase_2500,P62593,0.99498,NO,36,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.732,-2.234,-0.498,,0.555,H,A,0.75,1.17,2.26,,77.62,AAP,-1.91167,0.361275,0.00476483,0.99498 beta-lactamase_2500_E61N,beta-lactamase_2500_61,TEM-1,beta-lactamase_2500,P62593,0.994983,NO,61,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.115,-2.373,0.258,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.361275,0.00440955,0.994983 beta-lactamase_625_E56A,beta-lactamase_625_56,TEM-1,beta-lactamase_625,P62593,0.994984,NO,56,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.043,-2.078,0.035,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.213352,0.00238534,0.994984 beta-lactamase_625_E102M,beta-lactamase_625_102,TEM-1,beta-lactamase_625,P62593,0.994985,NO,102,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.118,-4.799,2.681,,0.722,S,B,1.04,1.82,1.336,,73.08,HAH,-1.581,0.213352,0.00486633,0.994985 beta-lactamase_156_V260A,beta-lactamase_156_260,TEM-1,beta-lactamase_156,P62593,0.994986,NO,260,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.111618,0.00471757,0.994986 beta-lactamase_39_E210L,beta-lactamase_39_210,TEM-1,beta-lactamase_39,P62593,0.99499,NO,210,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.319,-2.05,-0.269,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.0495842,0.00663582,0.99499 beta-lactamase_156_L196Q,beta-lactamase_156_196,TEM-1,beta-lactamase_156,P62593,0.994991,NO,196,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-2.478,-3.242,0.764,,0.518,S,A,0.55,1.35,7.897,,77.62,AHH,-1.839,0.111618,0.00512144,0.994991 beta-lactamase_625_L284Q,beta-lactamase_625_284,TEM-1,beta-lactamase_625,P62593,0.994992,NO,284,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.213352,0.0686156,0.994992 beta-lactamase_39_L219A,beta-lactamase_39_219,TEM-1,beta-lactamase_39,P62593,0.994998,NO,219,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.313,-3.187,1.874,,,I,A,0.55,-0.51,19.842,19.842,74.48,HHB,-1.21533,0.0495842,0.00664345,0.994998 beta-lactamase_156_A170T,beta-lactamase_156_170,TEM-1,beta-lactamase_156,P62593,0.994999,NO,170,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.237,-3.423,2.186,,0.126,,L,0.46,-0.35,3.7,,64.69,AHH,-1.63267,0.111618,0.00431903,0.994999 Pab1_N187H,Pab1_187,Pab1,Pab1,P04147,0.994999,NO,187,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-1.224,-3.968,2.744,,0.456,S,b,,1.87,,,,HPO,-1.272,0.175299,0.00083165,0.994999 beta-lactamase_2500_R275I,beta-lactamase_2500_275,TEM-1,beta-lactamase_2500,P62593,0.995,NO,275,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.397,-4.133,2.736,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.361275,0.0141984,0.995 beta-lactamase_625_A278C,beta-lactamase_625_278,TEM-1,beta-lactamase_625,P62593,0.995,NO,278,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.213352,0.0310297,0.995 Pab1_T159A,Pab1_159,Pab1,Pab1,P04147,0.995003,NO,159,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.445,-2.141,0.696,,,,,,,2.531,,79.03,HPA,-1.19467,0.175299,0.00133849,0.995003 beta-lactamase_156_G216P,beta-lactamase_156_216,TEM-1,beta-lactamase_156,P62593,0.995007,NO,216,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.477,-3.898,2.421,,0.437,I,A,0.29,-0.58,12.464,12.464,74.48,HOO,-1.68067,0.111618,0.00639568,0.995007 beta-lactamase_625_L150V,beta-lactamase_625_150,TEM-1,beta-lactamase_625,P62593,0.995009,NO,150,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.326,-2.348,1.022,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.213352,0.00463171,0.995009 beta-lactamase_625_L196A,beta-lactamase_625_196,TEM-1,beta-lactamase_625,P62593,0.99501,NO,196,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-2.478,-1.974,-0.504,,0.518,S,A,0.55,1.35,12.152,12.152,77.62,AHH,-1.839,0.213352,0.00512144,0.99501 beta-lactamase_625_L223K,beta-lactamase_625_223,TEM-1,beta-lactamase_625,P62593,0.995015,NO,223,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.055,-3.742,2.687,,0.27,,B,0.55,0.09,1.633,,74.48,HHO,-1.35033,0.213352,0.00372793,0.995015 beta-lactamase_P20R,beta-lactamase_20,TEM-1,beta-lactamase,P62593,0.995016,NO,20,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.74,-2.746,1.006,,,,,,,0.368,,67.83,HOH,-1.765,0.221079,0.00235322,0.995016 beta-lactamase_Q4Y,beta-lactamase_4,TEM-1,beta-lactamase,P62593,0.995016,NO,4,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,,-4.107,1.543,,,,,,,,,,HPB,,0.221079,0.00316562,0.995016 beta-lactamase_39_T269W,beta-lactamase_39_269,TEM-1,beta-lactamase_39,P62593,0.995019,NO,269,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.156,,,,0.646,H,A,0.53,0.4,3.889,,77.62,HPH,-1.96733,0.0495842,0.00950944,0.995019 beta-lactamase_156_G281T,beta-lactamase_156_281,TEM-1,beta-lactamase_156,P62593,0.995021,NO,281,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.111618,0.0406482,0.995021 beta-lactamase_156_G194C,beta-lactamase_156_194,TEM-1,beta-lactamase_156,P62593,0.995024,NO,194,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.396,-5.097,3.701,,0.276,S,b,0.29,0.36,1.346,,67.83,POA,-1.832,0.111618,0.00392163,0.995024 beta-lactamase_625_K109E,beta-lactamase_625_109,TEM-1,beta-lactamase_625,P62593,0.995024,NO,109,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.734,-2.478,0.744,,0.787,G,A,2.34,2.21,7.243,,72.73,ABB,-1.63333,0.213352,0.00462493,0.995024 beta-lactamase_625_P165D,beta-lactamase_625_165,TEM-1,beta-lactamase_625,P62593,0.995024,NO,165,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.373,-3.54,2.167,,0.203,T,A,0.52,-0.31,0.414,,73.78,AOA,-1.359,0.213352,0.00549538,0.995024 hsp90_Q582T,hsp90_582,hsp90,hsp90,P02829,0.995025,NO,582,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-3.278,-2.8,0,4.91603,0.453,S,B,,0.67,,,,OPH,-3.249,0.368192,0.000222939,0.995025 beta-lactamase_2500_K254A,beta-lactamase_2500_254,TEM-1,beta-lactamase_2500,P62593,0.995032,NO,254,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.361275,0.00369,0.995032 beta-lactamase_39_R118F,beta-lactamase_39_118,TEM-1,beta-lactamase_39,P62593,0.995033,NO,118,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.413,-4.338,1.925,,0.457,H,A,1.2,1.39,3.961,,77.62,HBA,-1.785,0.0495842,0.00538794,0.995033 beta-lactamase_625_R202M,beta-lactamase_625_202,TEM-1,beta-lactamase_625,P62593,0.995034,NO,202,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.292,-4.499,3.207,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.213352,0.00321899,0.995034 kka2_1:8_Q26D,kka2_1:8_26,Kka2,kka2_1:8,P00552,0.995034,NO,26,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.18,-3.048,0.868,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.100394,0.00708962,0.995034 kka2_1:8_Q26D,kka2_1:8_26,Kka2,kka2_1:8,P00552,0.995034,NO,26,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.18,-3.048,0.868,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.100394,0.00708962,0.995034 beta-lactamase_39_S233A,beta-lactamase_39_233,TEM-1,beta-lactamase_39,P62593,0.995035,NO,233,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.886,-2.424,0.538,,0.016,E,B,0.27,-1.01,5.361,,77.62,BPO,-1.17267,0.0495842,0.00311415,0.995035 beta-lactamase_625_D271G,beta-lactamase_625_271,TEM-1,beta-lactamase_625,P62593,0.995043,NO,271,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.213352,0.00752082,0.995043 beta-lactamase_625_G265Q,beta-lactamase_625_265,TEM-1,beta-lactamase_625,P62593,0.995046,NO,265,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-2.58,-2.659,0.079,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.213352,0.00811926,0.995046 beta-lactamase_156_I277T,beta-lactamase_156_277,TEM-1,beta-lactamase_156,P62593,0.995051,NO,277,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.111618,0.0169305,0.995051 beta-lactamase_156_P217L,beta-lactamase_156_217,TEM-1,beta-lactamase_156,P62593,0.995062,NO,217,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-2.062,-3.634,1.572,,0.496,I,A,0.52,-0.33,2.303,,74.48,OOH,-1.64333,0.111618,0.00463211,0.995062 beta-lactamase_156_F64M,beta-lactamase_156_64,TEM-1,beta-lactamase_156,P62593,0.995063,NO,64,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-0.841,-4.255,3.414,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.111618,0.000947691,0.995063 beta-lactamase_2500_H110N,beta-lactamase_2500_110,TEM-1,beta-lactamase_2500,P62593,0.995063,NO,110,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-1.706,-3.626,1.92,,0.341,G,a,0.17,1.08,31.31,31.31,64.69,BBH,-1.73333,0.361275,0.00441499,0.995063 beta-lactamase_156_S104T,beta-lactamase_156_104,TEM-1,beta-lactamase_156,P62593,0.995065,NO,104,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.015,-3.098,2.083,,0.04,,b,0.27,0.57,4.02,,63.29,HPO,-1.05267,0.111618,0.00218083,0.995065 kka2_1:2_S251S,kka2_1:2_251,Kka2,kka2_1:2,P00552,0.995071,NO,251,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.636,-2.636,,,0.712,H,A,0.27,-0.25,32.832,32.832,71.59,APP,-2.09367,0.295029,0.0138916,0.995071 beta-lactamase_39_G76T,beta-lactamase_39_76,TEM-1,beta-lactamase_39,P62593,0.995073,NO,76,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.189,-2.655,1.466,,,H,A,0.29,-0.67,2.145,,67.83,OOH,-1.22267,0.0495842,0.00476637,0.995073 beta-lactamase_156_T269E,beta-lactamase_156_269,TEM-1,beta-lactamase_156,P62593,0.995074,NO,269,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.111618,0.00950944,0.995074 beta-lactamase_156_P172K,beta-lactamase_156_172,TEM-1,beta-lactamase_156,P62593,0.995075,NO,172,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.998,-3.522,2.524,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.111618,0.00312594,0.995075 beta-lactamase_625_L160S,beta-lactamase_625_160,TEM-1,beta-lactamase_625,P62593,0.995075,NO,160,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.977,-3.653,2.676,,0.022,,B,0.55,-0.6,0.237,,44.41,BHA,-0.936,0.213352,0.00193775,0.995075 beta-lactamase_625_G85N,beta-lactamase_625_85,TEM-1,beta-lactamase_625,P62593,0.995083,NO,85,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.011,-3.501,2.49,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.213352,0.00252173,0.995083 beta-lactamase_2500_E238M,beta-lactamase_2500_238,TEM-1,beta-lactamase_2500,P62593,0.995085,NO,238,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.361275,0.00743256,0.995085 Pab1_A178D,Pab1_178,Pab1,Pab1,P04147,0.995087,NO,178,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.579,-2.055,0.476,,0.019,H,A,0.64,0.64,2.7,,81.63,OHH,-1.61067,0.175299,0.00160192,0.995087 beta-lactamase_156_R91V,beta-lactamase_156_91,TEM-1,beta-lactamase_156,P62593,0.995088,NO,91,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.392,-3.661,2.269,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.111618,0.00380226,0.995088 beta-lactamase_39_A148V,beta-lactamase_39_148,TEM-1,beta-lactamase_39,P62593,0.995089,NO,148,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.757,-3.631,1.874,,0.379,H,A,0.46,-0.55,3.551,,72.73,PHH,-1.40167,0.0495842,0.00547053,0.995089 beta-lactamase_625_L196D,beta-lactamase_625_196,TEM-1,beta-lactamase_625,P62593,0.99509,NO,196,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-2.478,-3.862,1.384,,0.518,S,A,0.55,1.35,12.152,12.152,77.62,AHH,-1.839,0.213352,0.00512144,0.99509 Pab1_I183Q,Pab1_183,Pab1,Pab1,P04147,0.99509,NO,183,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.302,-4.16,2.858,,0.308,T,B,1,1.08,1.29,,75.56,HHA,-1.27167,0.175299,0.000574345,0.99509 beta-lactamase_625_T69S,beta-lactamase_625_69,TEM-1,beta-lactamase_625,P62593,0.995091,NO,69,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-0.973,-2.405,1.432,,,G,A,0.22,-1.24,2.716,,93.01,PPH,-1.01833,0.213352,0.00127498,0.995091 beta-lactamase_0_P143G,beta-lactamase_0_143,TEM-1,beta-lactamase_0,P62593,0.995094,NO,143,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.967,-3.499,2.532,,0.075,H,A,0.52,-0.37,11.868,11.868,66.78,OOB,-1.354,0.0500837,0.00114551,0.995094 beta-lactamase_625_D99I,beta-lactamase_625_99,TEM-1,beta-lactamase_625,P62593,0.995094,NO,99,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.191,-3.979,2.788,,0.402,G,A,0.75,0.36,1.318,,64.69,PAH,-1.794,0.213352,0.00305446,0.995094 beta-lactamase_156_L248T,beta-lactamase_156_248,TEM-1,beta-lactamase_156,P62593,0.9951,NO,248,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.111618,0.00428493,0.9951 beta-lactamase_E169D,beta-lactamase_169,TEM-1,beta-lactamase,P62593,0.9951,NO,169,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.23,-3.13,1.9,5.78896,0.337,,A,0.52,1,1.806,,73.08,PAH,-1.16533,0.221079,0.00400994,0.9951 beta-lactamase_156_T198I,beta-lactamase_156_198,TEM-1,beta-lactamase_156,P62593,0.995106,NO,198,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.168,-3.831,1.663,,0.489,,B,0.22,-0.13,10.771,10.771,73.78,HPH,-1.98767,0.111618,0.004311,0.995106 beta-lactamase_156_T27F,beta-lactamase_156_27,TEM-1,beta-lactamase_156,P62593,0.995108,NO,27,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.905,-2.968,1.063,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.111618,0.00306559,0.995108 beta-lactamase_625_G194P,beta-lactamase_625_194,TEM-1,beta-lactamase_625,P62593,0.995108,NO,194,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.396,-3.912,2.516,,0.276,S,b,0.29,0.36,3.593,,67.83,POA,-1.832,0.213352,0.00392163,0.995108 beta-lactamase_625_G253L,beta-lactamase_625_253,TEM-1,beta-lactamase_625,P62593,0.995113,NO,253,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.213352,0.00786358,0.995113 beta-lactamase_E169Q,beta-lactamase_169,TEM-1,beta-lactamase,P62593,0.995113,NO,169,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.23,-2.523,1.293,5.78896,0.337,,A,0.52,1,1.806,,73.08,PAH,-1.16533,0.221079,0.00400994,0.995113 beta-lactamase_156_G154E,beta-lactamase_156_154,TEM-1,beta-lactamase_156,P62593,0.995115,NO,154,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.823,-3.512,2.689,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.111618,0.00180205,0.995115 beta-lactamase_625_L89F,beta-lactamase_625_89,TEM-1,beta-lactamase_625,P62593,0.995115,NO,89,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.096,-3.844,2.748,,0.168,T,A,0.55,0.63,1.599,,64.34,PHO,-1.75767,0.213352,0.00207068,0.995115 beta-lactamase_39_T131C,beta-lactamase_39_131,TEM-1,beta-lactamase_39,P62593,0.995117,NO,131,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.328,-3.123,1.795,,,H,A,0.22,-0.69,3.306,,67.48,PPH,-1.00867,0.0495842,0.00345886,0.995117 beta-lactamase_625_G265R,beta-lactamase_625_265,TEM-1,beta-lactamase_625,P62593,0.995119,NO,265,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.213352,0.00811926,0.995119 beta-lactamase_625_E279H,beta-lactamase_625_279,TEM-1,beta-lactamase_625,P62593,0.99512,NO,279,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.213352,0.0192826,0.99512 beta-lactamase_625_N168V,beta-lactamase_625_168,TEM-1,beta-lactamase_625,P62593,0.995121,NO,168,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-1.029,-3.632,2.603,,0.113,G,A,0.61,-0.4,1.014,,44.41,HPA,-1.13233,0.213352,0.00288667,0.995121 beta-lactamase_156_K213N,beta-lactamase_156_213,TEM-1,beta-lactamase_156,P62593,0.995122,NO,213,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.81,-3.623,1.813,,0.67,,A,2.34,0.29,3.924,,67.83,ABH,-1.57767,0.111618,0.00610411,0.995122 beta-lactamase_39_I140M,beta-lactamase_39_140,TEM-1,beta-lactamase_39,P62593,0.995124,NO,140,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.733,-4.137,2.404,,0.128,H,A,0.48,0.41,1.16,,73.08,PHO,-1.48733,0.0495842,0.00597777,0.995124 beta-lactamase_2500_A148G,beta-lactamase_2500_148,TEM-1,beta-lactamase_2500,P62593,0.995128,NO,148,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.757,-2.542,0.785,,0.379,H,A,0.46,-0.55,2.117,,72.73,PHH,-1.40167,0.361275,0.00547053,0.995128 beta-lactamase_0_G236T,beta-lactamase_0_236,TEM-1,beta-lactamase_0,P62593,0.995129,NO,236,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.784,-3.55,2.766,,0.241,,b,0.29,-0.59,3.506,,64.69,HOO,-1.025,0.0500837,0.00162372,0.995129 kka2_1:8_A166S,kka2_1:8_166,Kka2,kka2_1:8,P00552,0.995134,NO,166,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.407,-1.802,-0.605,,0.534,,B,1.04,1.03,13.995,13.995,71.59,HHO,-2.421,0.100394,0.00799912,0.995134 kka2_1:8_A166S,kka2_1:8_166,Kka2,kka2_1:8,P00552,0.995134,NO,166,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.407,-1.802,-0.605,,0.534,,B,1.04,1.03,13.995,13.995,71.59,HHO,-2.421,0.100394,0.00799912,0.995134 kka2_1:2_E230G,kka2_1:2_230,Kka2,kka2_1:2,P00552,0.995135,NO,230,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.672,-3.574,0.902,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.295029,0.00920051,0.995135 Pab1_E161D,Pab1_161,Pab1,Pab1,P04147,0.995135,NO,161,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.474,-1.926,0.452,,0.663,T,a,,1.34,,,,AAP,-1.59067,0.175299,0.00276141,0.995135 beta-lactamase_156_L47A,beta-lactamase_156_47,TEM-1,beta-lactamase_156,P62593,0.995136,NO,47,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.876,-3.301,1.425,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.111618,0.00439844,0.995136 Pab1_A185E,Pab1_185,Pab1,Pab1,P04147,0.995139,NO,185,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.702,-3.297,1.595,,,,,,,1.756,,63.26,AHH,-1.66167,0.175299,0.00144499,0.995139 PSD95pdz3_D366E,PSD95pdz3_366,PSD95pdz3,PSD95pdz3,P31016,0.995141,NO,366,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.264,-2.447,1.183,5.55684,,,,,20.2375,,,,HAH,-1.401,0.0758425,0.000481272,0.995141 beta-lactamase_39_V31S,beta-lactamase_39_31,TEM-1,beta-lactamase_39,P62593,0.995142,NO,31,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.822,-3.594,1.772,,,H,A,0.44,-0.46,2.885,,73.78,BHB,-2.03767,0.0495842,0.00478065,0.995142 beta-lactamase_2500_E169S,beta-lactamase_2500_169,TEM-1,beta-lactamase_2500,P62593,0.99515,NO,169,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.23,-2.21,0.98,,0.337,,A,1.04,1,1.806,,73.08,PAH,-1.16533,0.361275,0.00400994,0.99515 beta-lactamase_625_R162G,beta-lactamase_625_162,TEM-1,beta-lactamase_625,P62593,0.995151,NO,162,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.016,-3.445,2.429,,0.124,S,B,1.2,-0.37,1.445,,64.69,ABH,-1.25,0.213352,0.000561334,0.995151 beta-lactamase_156_H156D,beta-lactamase_156_156,TEM-1,beta-lactamase_156,P62593,0.995157,NO,156,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-3.156,-2.458,-0.698,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.111618,0.00468596,0.995157 beta-lactamase_156_K32V,beta-lactamase_156_32,TEM-1,beta-lactamase_156,P62593,0.995159,NO,32,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.984,-3.477,1.493,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.111618,0.00401283,0.995159 beta-lactamase_625_W163P,beta-lactamase_625_163,TEM-1,beta-lactamase_625,P62593,0.995166,NO,163,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-1.843,-4.201,2.358,,0.467,,B,0.47,-0.5,5.019,,63.99,BHA,-1.269,0.213352,0.00418955,0.995166 beta-lactamase_39_A247E,beta-lactamase_39_247,TEM-1,beta-lactamase_39,P62593,0.995167,NO,247,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.0495842,0.00611275,0.995167 beta-lactamase_L49I,beta-lactamase_49,TEM-1,beta-lactamase,P62593,0.995167,NO,49,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.897,-3.523,1.626,5.86005,0.131,T,A,1.3,0.04,3.112,,64.69,AHP,-1.99233,0.221079,0.00401477,0.995167 beta-lactamase_2500_N50V,beta-lactamase_2500_50,TEM-1,beta-lactamase_2500,P62593,0.995173,NO,50,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-2.979,-2.913,-0.066,,0.912,T,A,0.61,1.24,1.581,,77.62,HPP,-2.134,0.361275,0.0047211,0.995173 beta-lactamase_625_Q204R,beta-lactamase_625_204,TEM-1,beta-lactamase_625,P62593,0.995173,NO,204,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-1.382,-2.322,0.94,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.213352,0.00364106,0.995173 kka2_1:1_D5D,kka2_1:1_5,Kka2,kka2_1:1,P00552,0.995174,NO,5,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.306,-1.306,,,,,,,,0.895,,71.59,PAO,-1.784,0.520039,0.00222864,0.995174 kka2_1:2_T73E,kka2_1:2_73,Kka2,kka2_1:2,P00552,0.995177,NO,73,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.51,-2.977,0.467,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.295029,0.00628605,0.995177 beta-lactamase_2500_I171Q,beta-lactamase_2500_171,TEM-1,beta-lactamase_2500,P62593,0.99518,NO,171,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-2.431,-3.168,0.737,,0.361,,B,0.48,0.53,1.66,,77.62,HHO,-1.55533,0.361275,0.00623355,0.99518 beta-lactamase_39_R41G,beta-lactamase_39_41,TEM-1,beta-lactamase_39,P62593,0.995182,NO,41,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-0.942,-3.321,2.379,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.0495842,0.00123327,0.995182 beta-lactamase_625_R189L,beta-lactamase_625_189,TEM-1,beta-lactamase_625,P62593,0.995186,NO,189,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.844,-3.611,1.767,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.213352,0.0050699,0.995186 beta-lactamase_39_N98L,beta-lactamase_39_98,TEM-1,beta-lactamase_39,P62593,0.99519,NO,98,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-2.973,-3.59,0.617,,0.963,G,A,0.61,1.35,14.853,14.853,77.62,PPA,-2.07867,0.0495842,0.00505389,0.99519 beta-lactamase_0_I245N,beta-lactamase_0_245,TEM-1,beta-lactamase_0,P62593,0.995194,NO,245,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.0500837,0.00391032,0.995194 beta-lactamase_625_L223M,beta-lactamase_625_223,TEM-1,beta-lactamase_625,P62593,0.995195,NO,223,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.055,-3.986,2.931,,0.27,,B,0.55,0.09,1.633,,74.48,HHO,-1.35033,0.213352,0.00372793,0.995195 beta-lactamase_39_R118D,beta-lactamase_39_118,TEM-1,beta-lactamase_39,P62593,0.995196,NO,118,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.413,-2.866,0.453,,0.457,H,A,1.2,1.39,3.961,,77.62,HBA,-1.785,0.0495842,0.00538794,0.995196 beta-lactamase_156_T187Q,beta-lactamase_156_187,TEM-1,beta-lactamase_156,P62593,0.995201,NO,187,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.401,-4.004,2.603,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.111618,0.00491782,0.995201 beta-lactamase_156_D207R,beta-lactamase_156_207,TEM-1,beta-lactamase_156,P62593,0.995205,NO,207,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.064,-2.841,0.777,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.111618,0.00592942,0.995205 beta-lactamase_625_S256Y,beta-lactamase_625_256,TEM-1,beta-lactamase_625,P62593,0.995211,NO,256,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.213352,0.00710634,0.995211 Pab1_H134I,Pab1_134,Pab1,Pab1,P04147,0.995211,NO,134,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-1.542,-3.942,2.4,,,,,,,,,,HBO,-1.346,0.175299,0.00116356,0.995211 beta-lactamase_625_G194Q,beta-lactamase_625_194,TEM-1,beta-lactamase_625,P62593,0.995212,NO,194,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.396,-3.925,2.529,,0.276,S,b,0.29,0.36,3.593,,67.83,POA,-1.832,0.213352,0.00392163,0.995212 beta-lactamase_39_G226A,beta-lactamase_39_226,TEM-1,beta-lactamase_39,P62593,0.995216,NO,226,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.461,-2.638,1.177,,0.701,T,l,0.29,-0.25,23.034,23.034,74.48,HOH,-1.42933,0.0495842,0.00665294,0.995216 beta-lactamase_39_H24Q,beta-lactamase_39_24,TEM-1,beta-lactamase_39,P62593,0.995221,NO,24,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-2.481,-2.604,0.123,,,,,,,2.708,,93.01,OBO,-2.0035,0.0495842,0.00238894,0.995221 beta-lactamase_2500_V157I,beta-lactamase_2500_157,TEM-1,beta-lactamase_2500,P62593,0.995222,NO,157,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.751,-2.621,0.87,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.361275,0.00506849,0.995222 beta-lactamase_156_R176N,beta-lactamase_156_176,TEM-1,beta-lactamase_156,P62593,0.995224,NO,176,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-0.863,-3.448,2.585,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.111618,0.00105554,0.995224 beta-lactamase_156_L188G,beta-lactamase_156_188,TEM-1,beta-lactamase_156,P62593,0.99523,NO,188,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.166,-3.699,2.533,,,H,A,0.55,-0.3,1.574,,60.14,PHB,-1.47033,0.111618,0.00295687,0.99523 beta-lactamase_39_L199G,beta-lactamase_39_199,TEM-1,beta-lactamase_39,P62593,0.995231,NO,199,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-2.942,-2.663,-0.279,,0.832,H,A,0.55,0.42,15.504,15.504,77.62,PHH,-2.32933,0.0495842,0.0048649,0.995231 beta-lactamase_156_D113F,beta-lactamase_156_113,TEM-1,beta-lactamase_156,P62593,0.995247,NO,113,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.829,-4.448,2.619,,0.665,T,A,0.75,0.91,2.973,,73.08,PAO,-1.703,0.111618,0.00474112,0.995247 beta-lactamase_39_A222V,beta-lactamase_39_222,TEM-1,beta-lactamase_39,P62593,0.995249,NO,222,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.103,-1.973,-0.13,,0.233,H,A,0.46,-0.25,1.448,,77.62,PHH,-1.63733,0.0495842,0.00466094,0.995249 beta-lactamase_2500_D207G,beta-lactamase_2500_207,TEM-1,beta-lactamase_2500,P62593,0.995254,NO,207,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.064,-2.283,0.219,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.361275,0.00592942,0.995254 beta-lactamase_D269I,beta-lactamase_269,TEM-1,beta-lactamase,P62593,0.995257,NO,269,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.156,-3.961,1.805,5.47645,0.646,H,A,0.23,0.4,21.796,21.796,77.62,HAA,-1.96733,0.221079,0.00950944,0.995257 beta-lactamase_L196P,beta-lactamase_196,TEM-1,beta-lactamase,P62593,0.995257,NO,196,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-2.478,-3.165,0.687,,0.518,S,A,0.55,1.35,,,77.62,AHH,-1.839,0.221079,0.00512144,0.995257 beta-lactamase_M127T,beta-lactamase_127,TEM-1,beta-lactamase,P62593,0.995257,NO,127,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-2.251,-2.593,0.342,5.40552,0.312,S,A,1.07,0.32,1.671,,72.73,PHP,-1.40433,0.221079,0.00437927,0.995257 beta-lactamase_0_E279T,beta-lactamase_0_279,TEM-1,beta-lactamase_0,P62593,0.995262,NO,279,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.0500837,0.0192826,0.995262 PSD95pdz3_Q374S,PSD95pdz3_374,PSD95pdz3,PSD95pdz3,P31016,0.995266,NO,374,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-1.699,-2.842,1.143,5.38825,,,,,17.3289,,,,APH,-1.47,0.0758425,0.000372298,0.995266 kka2_1:1_G43G,kka2_1:1_43,Kka2,kka2_1:1,P00552,0.995267,NO,43,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.587,-1.587,,,0.862,T,l,0.75,-0.67,2.247,,63.26,POB,-2.18533,0.520039,0.0071925,0.995267 beta-lactamase_2500_L167V,beta-lactamase_2500_167,TEM-1,beta-lactamase_2500,P62593,0.995269,NO,167,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.138,-2.277,1.139,,0.015,G,A,0.55,-0.63,7.813,,64.69,AHP,-1.30767,0.361275,0.00303566,0.995269 beta-lactamase_625_G39N,beta-lactamase_625_39,TEM-1,beta-lactamase_625,P62593,0.99527,NO,39,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.864,-2.55,0.686,,0.701,T,L,0.29,0.47,29.926,29.926,77.62,HOH,-1.53633,0.213352,0.00487611,0.99527 beta-lactamase_625_P165E,beta-lactamase_625_165,TEM-1,beta-lactamase_625,P62593,0.99527,NO,165,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.373,-3.511,2.138,,0.203,T,A,0.52,-0.31,0.414,,73.78,AOA,-1.359,0.213352,0.00549538,0.99527 beta-lactamase_156_Y103G,beta-lactamase_156_103,TEM-1,beta-lactamase_156,P62593,0.995273,NO,103,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-1.33,-3.527,2.197,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.111618,0.00443048,0.995273 beta-lactamase_39_T116W,beta-lactamase_39_116,TEM-1,beta-lactamase_39,P62593,0.995282,NO,116,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.28,-5.356,4.076,,0.115,E,B,0.22,-0.12,1.133,,67.48,HPH,-1.39967,0.0495842,0.00336175,0.995282 beta-lactamase_39_Y103H,beta-lactamase_39_103,TEM-1,beta-lactamase_39,P62593,0.995282,NO,103,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-1.33,-2.243,0.913,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.0495842,0.00443048,0.995282 beta-lactamase_625_T179S,beta-lactamase_625_179,TEM-1,beta-lactamase_625,P62593,0.995282,NO,179,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.085,-2.228,1.143,,,E,B,0.22,-1.38,0.367,,73.08,PPH,-1.557,0.213352,0.00226045,0.995282 beta-lactamase_39_A124N,beta-lactamase_39_124,TEM-1,beta-lactamase_39,P62593,0.995284,NO,124,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.181,-3.812,2.631,,,H,A,0.46,-0.9,1.367,,64.34,HHH,-1.152,0.0495842,0.00481399,0.995284 beta-lactamase_39_R189Q,beta-lactamase_39_189,TEM-1,beta-lactamase_39,P62593,0.995285,NO,189,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.844,-2.262,0.418,,0.278,H,A,1.2,1.01,12.11,12.11,72.73,HBB,-1.668,0.0495842,0.0050699,0.995285 kka2_1:2_N200G,kka2_1:2_200,Kka2,kka2_1:2,P00552,0.995285,NO,200,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-2.446,-1.948,-0.498,,0.756,T,L,0.61,-0.08,2.836,,64.39,APO,-2.08,0.295029,0.00838549,0.995285 beta-lactamase_I3L,beta-lactamase_3,TEM-1,beta-lactamase,P62593,0.995289,NO,3,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-2.143,-2.074,-0.069,,,,,,,3.946,,93.01,PHP,-2.21633,0.221079,0.00349304,0.995289 beta-lactamase_156_S96R,beta-lactamase_156_96,TEM-1,beta-lactamase_156,P62593,0.995291,NO,96,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.27,-2.133,-0.137,,0.368,,b,0.27,0.39,2.838,,73.78,HPP,-2.019,0.111618,0.00551835,0.995291 beta-lactamase_39_L197N,beta-lactamase_39_197,TEM-1,beta-lactamase_39,P62593,0.995291,NO,197,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.853,-4.12,3.267,,0.007,S,B,0.55,0.33,1.559,,60.14,HHP,-1.833,0.0495842,0.00144602,0.995291 beta-lactamase_625_Q276A,beta-lactamase_625_276,TEM-1,beta-lactamase_625,P62593,0.995292,NO,276,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-1.144,-3.872,2.728,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.213352,0.0191712,0.995292 beta-lactamase_2500_R239Y,beta-lactamase_2500_239,TEM-1,beta-lactamase_2500,P62593,0.995301,NO,239,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.361275,0.00213852,0.995301 kka2_1:2_A71M,kka2_1:2_71,Kka2,kka2_1:2,P00552,0.995312,NO,71,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.824,-3.582,1.758,,0.553,H,A,0.46,0.08,9.788,,64.39,HHP,-1.74033,0.295029,0.00727707,0.995312 beta-lactamase_625_Q203L,beta-lactamase_625_203,TEM-1,beta-lactamase_625,P62593,0.995316,NO,203,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.168,-2.697,0.529,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.213352,0.00631514,0.995316 beta-lactamase_39_L219N,beta-lactamase_39_219,TEM-1,beta-lactamase_39,P62593,0.995318,NO,219,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.313,-4.217,2.904,,,I,A,0.55,-0.51,19.842,19.842,74.48,HHB,-1.21533,0.0495842,0.00664345,0.995318 beta-lactamase_39_P172V,beta-lactamase_39_172,TEM-1,beta-lactamase_39,P62593,0.99532,NO,172,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.998,-3.483,2.485,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.0495842,0.00312594,0.99532 beta-lactamase_625_N168G,beta-lactamase_625_168,TEM-1,beta-lactamase_625,P62593,0.995329,NO,168,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-1.029,-3.01,1.981,,0.113,G,A,0.61,-0.4,1.014,,44.41,HPA,-1.13233,0.213352,0.00288667,0.995329 beta-lactamase_625_G226A,beta-lactamase_625_226,TEM-1,beta-lactamase_625,P62593,0.995331,NO,226,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.461,-2.638,1.177,,0.701,T,l,0.29,-0.25,3.199,,74.48,HOH,-1.42933,0.213352,0.00665294,0.995331 beta-lactamase_39_N173Q,beta-lactamase_39_173,TEM-1,beta-lactamase_39,P62593,0.995334,NO,173,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-2.663,-4.003,1.34,,1.044,T,l,0.61,1.25,1.426,,77.62,OPA,-1.46633,0.0495842,0.0033769,0.995334 beta-lactamase_0_M153Q,beta-lactamase_0_153,TEM-1,beta-lactamase_0,P62593,0.995338,NO,153,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-3.193,-4.202,1.009,,0.14,T,A,0.55,-0.11,3.826,,77.62,PHO,-2.25767,0.0500837,0.00509109,0.995338 Pab1_G193A,Pab1_193,Pab1,Pab1,P04147,0.995344,NO,193,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.414,-3.036,1.622,,,,,,,,,,POP,-1.55733,0.175299,0.0014922,0.995344 beta-lactamase_156_Y95I,beta-lactamase_156_95,TEM-1,beta-lactamase_156,P62593,0.995345,NO,95,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-1.715,-1.963,0.248,,0.122,,b,0.21,-0.37,2.341,,77.62,BHP,-2.16167,0.111618,0.00479449,0.995345 beta-lactamase_156_R275G,beta-lactamase_156_275,TEM-1,beta-lactamase_156,P62593,0.995346,NO,275,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.111618,0.0141984,0.995346 beta-lactamase_E145M,beta-lactamase_145,TEM-1,beta-lactamase,P62593,0.995358,NO,145,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.357,-4.807,2.45,5.38104,0.545,H,A,0.52,0.79,2.124,,77.62,BAH,-2.069,0.221079,0.00553285,0.995358 beta-lactamase_I45M,beta-lactamase_45,TEM-1,beta-lactamase,P62593,0.995358,NO,45,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-2.421,-3.375,0.954,5.31505,,E,B,1,-0.3,2.256,,77.62,HHA,-2.30267,0.221079,0.00452842,0.995358 beta-lactamase_K190A,beta-lactamase_190,TEM-1,beta-lactamase,P62593,0.995358,NO,190,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.994,-2.146,0.152,5.49163,0.371,H,A,1.82,0.16,29.753,29.753,77.62,BBH,-1.64167,0.221079,0.00574527,0.995358 beta-lactamase_156_A123N,beta-lactamase_156_123,TEM-1,beta-lactamase_156,P62593,0.995361,NO,123,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.834,-3.947,3.113,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.111618,0.0010157,0.995361 beta-lactamase_156_H94C,beta-lactamase_156_94,TEM-1,beta-lactamase_156,P62593,0.995368,NO,94,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-2.5,-5.143,2.643,,0.776,,B,0.17,1.24,11.583,11.583,77.62,HBH,-1.872,0.111618,0.00389226,0.995368 beta-lactamase_625_Q267V,beta-lactamase_625_267,TEM-1,beta-lactamase_625,P62593,0.995369,NO,267,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.213352,0.0102128,0.995369 beta-lactamase_0_P181Y,beta-lactamase_0_181,TEM-1,beta-lactamase_0,P62593,0.995371,NO,181,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.813,-4.385,3.572,,,H,A,0.52,-1.14,1.357,,61.54,HOH,-1.795,0.0500837,0.000703122,0.995371 beta-lactamase_39_M127V,beta-lactamase_39_127,TEM-1,beta-lactamase_39,P62593,0.995374,NO,127,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-2.251,-2.333,0.082,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.0495842,0.00437927,0.995374 beta-lactamase_39_I54M,beta-lactamase_39_54,TEM-1,beta-lactamase_39,P62593,0.995382,NO,54,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-2.838,-3.13,0.292,,0.669,E,B,0.48,-0.14,1.349,,73.78,BHH,-2.337,0.0495842,0.00403589,0.995382 kka2_1:4_R143L,kka2_1:4_143,Kka2,kka2_1:4,P00552,0.995386,NO,143,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.525,-2.21,-0.315,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.168804,0.00662247,0.995386 beta-lactamase_156_R189S,beta-lactamase_156_189,TEM-1,beta-lactamase_156,P62593,0.995389,NO,189,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.844,-2.849,1.005,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.111618,0.0050699,0.995389 beta-lactamase_156_L55Q,beta-lactamase_156_55,TEM-1,beta-lactamase_156,P62593,0.995391,NO,55,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.86,-3.156,1.296,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.111618,0.00403741,0.995391 beta-lactamase_0_R257Y,beta-lactamase_0_257,TEM-1,beta-lactamase_0,P62593,0.995393,NO,257,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.0500837,0.00756629,0.995393 beta-lactamase_156_A34T,beta-lactamase_156_34,TEM-1,beta-lactamase_156,P62593,0.995393,NO,34,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.059,-2.5,0.441,,,H,A,0.46,-0.54,3.614,,73.78,AHA,-1.74967,0.111618,0.00407913,0.995393 beta-lactamase_2500_Q86M,beta-lactamase_2500_86,TEM-1,beta-lactamase_2500,P62593,0.995396,NO,86,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.4,-3.46,1.06,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.361275,0.00450027,0.995396 beta-lactamase_625_Q203R,beta-lactamase_625_203,TEM-1,beta-lactamase_625,P62593,0.995397,NO,203,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.168,-2.451,0.283,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.213352,0.00631514,0.995397 beta-lactamase_625_E169D,beta-lactamase_625_169,TEM-1,beta-lactamase_625,P62593,0.995399,NO,169,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.23,-3.13,1.9,,0.337,,A,1.04,1,1.806,,73.08,PAH,-1.16533,0.213352,0.00400994,0.995399 beta-lactamase_39_P25Y,beta-lactamase_39_25,TEM-1,beta-lactamase_39,P62593,0.995402,NO,25,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.526,-4.327,2.801,,0.624,H,A,0.52,0.14,1.157,,73.08,BOA,-2.15367,0.0495842,0.00347571,0.995402 beta-lactamase_P60H,beta-lactamase_60,TEM-1,beta-lactamase,P62593,0.995403,NO,60,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-2.469,-3.266,0.797,5.51353,0.256,T,A,0.73,-0.56,3.653,,77.62,BOA,-1.97633,0.221079,0.00521318,0.995403 beta-lactamase_625_E62W,beta-lactamase_625_62,TEM-1,beta-lactamase_625,P62593,0.995405,NO,62,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.193,-5.409,4.216,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.213352,0.00264802,0.995405 beta-lactamase_625_F70L,beta-lactamase_625_70,TEM-1,beta-lactamase_625,P62593,0.995406,NO,70,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.169,-2.96,1.791,,,H,A,0.58,-1.34,1.14,,63.99,PHB,-0.980667,0.213352,0.00193499,0.995406 beta-lactamase_156_T139K,beta-lactamase_156_139,TEM-1,beta-lactamase_156,P62593,0.995407,NO,139,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.901,-3.403,1.502,,0.216,H,A,0.22,0.39,16.34,16.34,77.62,PPH,-2.04667,0.111618,0.00441837,0.995407 beta-lactamase_39_S104K,beta-lactamase_39_104,TEM-1,beta-lactamase_39,P62593,0.995411,NO,104,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.015,-3.372,2.357,,0.04,,b,0.27,0.57,4.02,,63.29,HPO,-1.05267,0.0495842,0.00218083,0.995411 beta-lactamase_625_V157R,beta-lactamase_625_157,TEM-1,beta-lactamase_625,P62593,0.995412,NO,157,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.751,-3.07,1.319,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.213352,0.00506849,0.995412 WW_domain_I193R,WW_domain_193,Yap65,WW_domain,P46937,0.995415,NO,193,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.993,-3.822,1.829,6.15906,,,,,,1.833,,83.33,BHA,-1.756,0.153962,0.00587613,0.995415 beta-lactamase_39_N98P,beta-lactamase_39_98,TEM-1,beta-lactamase_39,P62593,0.995421,NO,98,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-2.973,-3.946,0.973,,0.963,G,A,0.61,1.35,14.853,14.853,77.62,PPA,-2.07867,0.0495842,0.00505389,0.995421 beta-lactamase_156_S256A,beta-lactamase_156_256,TEM-1,beta-lactamase_156,P62593,0.995425,NO,256,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.111618,0.00710634,0.995425 Pab1_E175H,Pab1_175,Pab1,Pab1,P04147,0.995437,NO,175,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.055,-2.89,0.835,,,,,,,,,,AAA,-1.82667,0.175299,0.00203137,0.995437 beta-lactamase_625_A84C,beta-lactamase_625_84,TEM-1,beta-lactamase_625,P62593,0.995439,NO,84,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.651,-5.003,3.352,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.213352,0.00503822,0.995439 beta-lactamase_39_A40R,beta-lactamase_39_40,TEM-1,beta-lactamase_39,P62593,0.99544,NO,40,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.402,-3.924,2.522,,0.155,S,B,0.46,0.21,0.783,,73.78,OHB,-1.40267,0.0495842,0.00490026,0.99544 beta-lactamase_2500_D36L,beta-lactamase_2500_36,TEM-1,beta-lactamase_2500,P62593,0.995442,NO,36,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.732,-3.628,0.896,,0.555,H,A,0.75,1.17,2.26,,77.62,AAP,-1.91167,0.361275,0.00476483,0.995442 PSD95pdz3_Q374R,PSD95pdz3_374,PSD95pdz3,PSD95pdz3,P31016,0.995447,NO,374,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-1.699,-2.94,1.241,5.38825,,,,,17.3289,,,,APH,-1.47,0.0758425,0.000372298,0.995447 beta-lactamase_156_E175S,beta-lactamase_156_175,TEM-1,beta-lactamase_156,P62593,0.995448,NO,175,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.336,-2.863,0.527,,0.551,,A,1.04,1.05,2.334,,77.62,AAB,-1.31233,0.111618,0.00482205,0.995448 beta-lactamase_625_T263S,beta-lactamase_625_263,TEM-1,beta-lactamase_625,P62593,0.995449,NO,263,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.213352,0.0110582,0.995449 beta-lactamase_E195E,beta-lactamase_195,TEM-1,beta-lactamase,P62593,0.99545,NO,195,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.186,-2.186,,7.28489,1.016,S,A,1.52,0.85,2.583,,77.62,OAH,-2.02,0.221079,0.00496565,0.99545 beta-lactamase_625_E166F,beta-lactamase_625_166,TEM-1,beta-lactamase_625,P62593,0.995452,NO,166,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.756,-4.345,2.589,,0.508,G,A,1.04,1.05,2.124,,73.08,OAH,-1.42233,0.213352,0.00512989,0.995452 beta-lactamase_156_T158V,beta-lactamase_156_158,TEM-1,beta-lactamase_156,P62593,0.995456,NO,158,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.116,-3.299,2.183,,0.036,,B,0.22,-0.85,3.771,,69.58,HPB,-1.269,0.111618,0.00341825,0.995456 beta-lactamase_156_G52T,beta-lactamase_156_52,TEM-1,beta-lactamase_156,P62593,0.995463,NO,52,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.149,-3.586,2.437,,0.299,,l,0.29,-0.04,1.179,,64.69,POB,-1.66267,0.111618,0.00340138,0.995463 beta-lactamase_2500_A282S,beta-lactamase_2500_282,TEM-1,beta-lactamase_2500,P62593,0.995464,NO,282,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.361275,0.0449821,0.995464 beta-lactamase_625_M153T,beta-lactamase_625_153,TEM-1,beta-lactamase_625,P62593,0.995464,NO,153,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-3.193,-2.237,-0.956,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.213352,0.00509109,0.995464 beta-lactamase_2500_Q267V,beta-lactamase_2500_267,TEM-1,beta-lactamase_2500,P62593,0.995465,NO,267,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.361275,0.0102128,0.995465 beta-lactamase_39_G154E,beta-lactamase_39_154,TEM-1,beta-lactamase_39,P62593,0.995466,NO,154,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.823,-3.512,2.689,,0.54,T,l,0.29,-0.56,1.151,,64.69,HOA,-1.635,0.0495842,0.00180205,0.995466 beta-lactamase_156_E46D,beta-lactamase_156_46,TEM-1,beta-lactamase_156,P62593,0.995467,NO,46,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.94,-3.652,1.712,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.111618,0.00427568,0.995467 beta-lactamase_625_G243A,beta-lactamase_625_243,TEM-1,beta-lactamase_625,P62593,0.995469,NO,243,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.213352,0.00464034,0.995469 beta-lactamase_625_T139C,beta-lactamase_625_139,TEM-1,beta-lactamase_625,P62593,0.995469,NO,139,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.901,-4.964,3.063,,0.216,H,A,0.22,0.39,2.256,,77.62,PPH,-2.04667,0.213352,0.00441837,0.995469 beta-lactamase_156_E102D,beta-lactamase_156_102,TEM-1,beta-lactamase_156,P62593,0.99547,NO,102,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.118,-2.118,0,,0.722,S,B,1.04,1.82,15.721,15.721,73.08,HAH,-1.581,0.111618,0.00486633,0.99547 PSD95pdz3_G345Q,PSD95pdz3_345,PSD95pdz3,PSD95pdz3,P31016,0.995474,NO,345,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.008,-3.806,2.798,4.32868,,,,,13.165,,,,OOO,-1.084,0.0758425,0.000771806,0.995474 beta-lactamase_N50K,beta-lactamase_50,TEM-1,beta-lactamase,P62593,0.995475,NO,50,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-2.979,-3.578,0.599,5.51261,0.912,T,A,1.07,1.24,1.581,,77.62,HPP,-2.134,0.221079,0.0047211,0.995475 beta-lactamase_2500_A77Y,beta-lactamase_2500_77,TEM-1,beta-lactamase_2500,P62593,0.995486,NO,77,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.234,-4.173,2.939,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.361275,0.00282362,0.995486 beta-lactamase_156_L73N,beta-lactamase_156_73,TEM-1,beta-lactamase_156,P62593,0.995488,NO,73,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.507,-4.234,2.727,,,H,A,0.55,-0.64,2.09,,67.83,HHH,-1.487,0.111618,0.00488983,0.995488 beta-lactamase_39_E145R,beta-lactamase_39_145,TEM-1,beta-lactamase_39,P62593,0.99549,NO,145,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.357,-2.676,0.319,,0.545,H,A,1.04,0.79,1.199,,77.62,BAH,-2.069,0.0495842,0.00553285,0.99549 beta-lactamase_625_I54C,beta-lactamase_625_54,TEM-1,beta-lactamase_625,P62593,0.995492,NO,54,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-2.838,-5.056,2.218,,0.669,E,B,0.48,-0.14,3.946,,73.78,BHH,-2.337,0.213352,0.00403589,0.995492 beta-lactamase_625_L196W,beta-lactamase_625_196,TEM-1,beta-lactamase_625,P62593,0.995496,NO,196,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-2.478,-5.492,3.014,,0.518,S,A,0.55,1.35,12.152,12.152,77.62,AHH,-1.839,0.213352,0.00512144,0.995496 beta-lactamase_156_D83M,beta-lactamase_156_83,TEM-1,beta-lactamase_156,P62593,0.995498,NO,83,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.066,-4.912,3.846,,0.354,H,A,0.75,0.22,1.281,,48.95,HAH,-1.34733,0.111618,0.00205968,0.995498 beta-lactamase_625_G194A,beta-lactamase_625_194,TEM-1,beta-lactamase_625,P62593,0.995501,NO,194,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.396,-2.558,1.162,,0.276,S,b,0.29,0.36,3.593,,67.83,POA,-1.832,0.213352,0.00392163,0.995501 beta-lactamase_2500_Q97S,beta-lactamase_2500_97,TEM-1,beta-lactamase_2500,P62593,0.995504,NO,97,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.072,-3.388,1.316,,0.823,G,A,0.64,2.42,1.157,,77.62,PPP,-2.43833,0.361275,0.0045116,0.995504 beta-lactamase_156_T126E,beta-lactamase_156_126,TEM-1,beta-lactamase_156,P62593,0.995505,NO,126,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.122,-3.395,2.273,,0.05,H,A,0.22,-0.05,1.14,,44.41,HPH,-1.60467,0.111618,0.00244552,0.995505 beta-lactamase_156_P65T,beta-lactamase_156_65,TEM-1,beta-lactamase_156,P62593,0.995507,NO,65,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.894,-3.44,2.546,,0.098,E,B,0.52,-0.62,0.623,,40.56,HOH,-1.03233,0.111618,0.00152776,0.995507 beta-lactamase_2500_E195K,beta-lactamase_2500_195,TEM-1,beta-lactamase_2500,P62593,0.995507,NO,195,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.186,-2.529,0.343,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.361275,0.00496565,0.995507 beta-lactamase_156_A235V,beta-lactamase_156_235,TEM-1,beta-lactamase_156,P62593,0.995513,NO,235,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.266,-2.665,1.399,,0.32,E,B,0.46,-0.86,1.344,,50,OHO,-0.89,0.111618,0.00493474,0.995513 beta-lactamase_156_R220M,beta-lactamase_156_220,TEM-1,beta-lactamase_156,P62593,0.995514,NO,220,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-0.942,-4.506,3.564,,0.295,I,A,1.2,-0.76,2.164,,74.48,HBP,-1.33633,0.111618,0.00232421,0.995514 beta-lactamase_39_G253P,beta-lactamase_39_253,TEM-1,beta-lactamase_39,P62593,0.995515,NO,253,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-2.253,-2.791,0.538,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.0495842,0.00786358,0.995515 beta-lactamase_K53Y,beta-lactamase_53,TEM-1,beta-lactamase,P62593,0.995517,NO,53,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-2.313,-4.187,1.874,5.93654,0.589,,B,1.82,1.15,19.72,19.72,77.62,OBH,-2.1,0.221079,0.00383383,0.995517 beta-lactamase_T186K,beta-lactamase_186,TEM-1,beta-lactamase,P62593,0.995517,NO,186,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.522,-2.678,0.156,5.07364,0.396,H,A,0.3,-0.28,2.144,,77.62,HPP,-1.77633,0.221079,0.00485034,0.995517 beta-lactamase_39_S57L,beta-lactamase_39_57,TEM-1,beta-lactamase_39,P62593,0.995521,NO,57,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.918,-2.848,0.93,,0.352,E,B,0.27,-0.18,2.3,,72.73,APH,-2.29167,0.0495842,0.00492804,0.995521 beta-lactamase_625_S122H,beta-lactamase_625_122,TEM-1,beta-lactamase_625,P62593,0.995524,NO,122,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.406,-2.676,0.27,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.213352,0.00497825,0.995524 beta-lactamase_625_D174C,beta-lactamase_625_174,TEM-1,beta-lactamase_625,P62593,0.995528,NO,174,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.738,-5.087,4.349,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.213352,0.00125633,0.995528 beta-lactamase_156_H24L,beta-lactamase_156_24,TEM-1,beta-lactamase_156,P62593,0.995529,NO,24,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-2.481,-3.404,0.923,,,,,,,2.708,,93.01,OBO,-2.0035,0.111618,0.00238894,0.995529 beta-lactamase_625_E169V,beta-lactamase_625_169,TEM-1,beta-lactamase_625,P62593,0.995532,NO,169,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.23,-3.538,2.308,,0.337,,A,1.04,1,1.806,,73.08,PAH,-1.16533,0.213352,0.00400994,0.995532 beta-lactamase_39_S96V,beta-lactamase_39_96,TEM-1,beta-lactamase_39,P62593,0.995536,NO,96,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.27,-3.642,1.372,,0.368,,b,0.27,0.39,2.516,,73.78,HPP,-2.019,0.0495842,0.00551835,0.995536 beta-lactamase_625_E56M,beta-lactamase_625_56,TEM-1,beta-lactamase_625,P62593,0.995536,NO,56,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.043,-4.624,2.581,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.213352,0.00238534,0.995536 beta-lactamase_156_R242G,beta-lactamase_156_242,TEM-1,beta-lactamase_156,P62593,0.995537,NO,242,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.319,-3.802,2.483,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.111618,0.00452879,0.995537 beta-lactamase_156_E210V,beta-lactamase_156_210,TEM-1,beta-lactamase_156,P62593,0.99554,NO,210,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.319,-1.881,-0.438,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.111618,0.00663582,0.99554 beta-lactamase_2500_N152S,beta-lactamase_2500_152,TEM-1,beta-lactamase_2500,P62593,0.99555,NO,152,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-2.757,-1.988,-0.769,,0.863,H,A,0.61,0.92,2.061,,77.62,BPH,-2.97,0.361275,0.00471429,0.99555 beta-lactamase_0_E175I,beta-lactamase_0_175,TEM-1,beta-lactamase_0,P62593,0.995551,NO,175,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.336,-3.797,1.461,,0.551,,A,1.04,1.05,2.334,,77.62,AAB,-1.31233,0.0500837,0.00482205,0.995551 beta-lactamase_625_D99Q,beta-lactamase_625_99,TEM-1,beta-lactamase_625,P62593,0.995551,NO,99,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.191,-2.836,1.645,,0.402,G,A,0.75,0.36,1.318,,64.69,PAH,-1.794,0.213352,0.00305446,0.995551 beta-lactamase_39_T269C,beta-lactamase_39_269,TEM-1,beta-lactamase_39,P62593,0.995553,NO,269,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.156,,,,0.646,H,A,0.53,0.4,3.889,,77.62,HPH,-1.96733,0.0495842,0.00950944,0.995553 beta-lactamase_0_R63V,beta-lactamase_0_63,TEM-1,beta-lactamase_0,P62593,0.995559,NO,63,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-0.943,-3.626,2.683,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.0500837,0.00126938,0.995559 beta-lactamase_39_G90V,beta-lactamase_39_90,TEM-1,beta-lactamase_39,P62593,0.99556,NO,90,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-2.091,-3.033,0.942,,0.598,T,A,0.29,0.32,30.794,30.794,77.62,HOB,-1.52633,0.0495842,0.00490273,0.99556 beta-lactamase_156_A246V,beta-lactamase_156_246,TEM-1,beta-lactamase_156,P62593,0.995564,NO,246,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.121,-1.76,-0.361,,0.01,E,B,0.46,-1.01,1.959,,73.78,HHH,-1.55633,0.111618,0.00569458,0.995564 beta-lactamase_625_P224G,beta-lactamase_625_224,TEM-1,beta-lactamase_625,P62593,0.995566,NO,224,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.893,-3.351,2.458,,0.383,,B,0.52,-0.3,1.35,,74.48,HOH,-1.26433,0.213352,0.00189564,0.995566 beta-lactamase_156_T126L,beta-lactamase_156_126,TEM-1,beta-lactamase_156,P62593,0.995567,NO,126,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.122,-3.373,2.251,,0.05,H,A,0.22,-0.05,1.14,,44.41,HPH,-1.60467,0.111618,0.00244552,0.995567 beta-lactamase_R176Q,beta-lactamase_176,TEM-1,beta-lactamase,P62593,0.995569,NO,176,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-0.863,-3.449,2.586,5.61264,0.385,T,B,0.68,-0.63,,,,ABA,-1.38867,0.221079,0.00105554,0.995569 beta-lactamase_39_I125S,beta-lactamase_39_125,TEM-1,beta-lactamase_39,P62593,0.995576,NO,125,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.441,-2.843,1.402,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.0495842,0.00383964,0.995576 beta-lactamase_625_V82I,beta-lactamase_625_82,TEM-1,beta-lactamase_625,P62593,0.995577,NO,82,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.325,-2.197,0.872,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.213352,0.00397046,0.995577 beta-lactamase_156_G236D,beta-lactamase_156_236,TEM-1,beta-lactamase_156,P62593,0.995579,NO,236,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.784,-3.513,2.729,,0.241,,b,0.29,-0.59,1.883,,64.69,HOO,-1.025,0.111618,0.00162372,0.995579 beta-lactamase_625_H110Q,beta-lactamase_625_110,TEM-1,beta-lactamase_625,P62593,0.995579,NO,110,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-1.706,-2.734,1.028,,0.341,G,a,0.17,1.08,31.31,31.31,64.69,BBH,-1.73333,0.213352,0.00441499,0.995579 E1_Ubiquitin_F45C,E1_Ubiquitin_45,Uba1,E1_Ubiquitin,P0CG63,0.995579,NO,45,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.149,-4.679,3.53,,0.26,E,B,,-0.99,,,,HHH,-1.316,0.18783,0.00193245,0.995579 E1_Ubiquitin_K48G,E1_Ubiquitin_48,Uba1,E1_Ubiquitin,P0CG63,0.995579,NO,48,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.219,-3.229,2.01,,0.132,E,B,,-0.28,,,,OBO,-1.109,0.18783,0.00100363,0.995579 E1_Ubiquitin_K48V,E1_Ubiquitin_48,Uba1,E1_Ubiquitin,P0CG63,0.995579,NO,48,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.219,-3.399,2.18,,0.132,E,B,,-0.28,,,,OBO,-1.109,0.18783,0.00100363,0.995579 E1_Ubiquitin_L71E,E1_Ubiquitin_71,Uba1,E1_Ubiquitin,P0CG63,0.995579,NO,71,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.039,-3.707,2.668,,0.591,E,B,,-0.69,,,,BHB,-1.19433,0.18783,0.00148349,0.995579 beta-lactamase_39_I54D,beta-lactamase_39_54,TEM-1,beta-lactamase_39,P62593,0.99558,NO,54,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-2.838,-3.732,0.894,,0.669,E,B,0.48,-0.14,1.349,,73.78,BHH,-2.337,0.0495842,0.00403589,0.99558 beta-lactamase_156_A225I,beta-lactamase_156_225,TEM-1,beta-lactamase_156,P62593,0.995583,NO,225,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.845,-4.041,2.196,,1,T,B,0.46,-0.38,11.722,11.722,74.48,OHO,-1.39967,0.111618,0.00465057,0.995583 beta-lactamase_156_G234C,beta-lactamase_156_234,TEM-1,beta-lactamase_156,P62593,0.995583,NO,234,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.62,-5.087,4.467,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.111618,0.000889577,0.995583 beta-lactamase_156_W163L,beta-lactamase_156_163,TEM-1,beta-lactamase_156,P62593,0.995584,NO,163,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-1.843,-2.838,0.995,,0.467,,B,0.47,-0.5,15.095,15.095,63.99,BHA,-1.269,0.111618,0.00418955,0.995584 Pab1_L190I,Pab1_190,Pab1,Pab1,P04147,0.995587,NO,190,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.325,-2.991,1.666,,0.489,E,B,,2.59,,,,HHH,-1.31033,0.175299,0.00132347,0.995587 beta-lactamase_39_G76Y,beta-lactamase_39_76,TEM-1,beta-lactamase_39,P62593,0.995594,NO,76,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.189,-4.36,3.171,,,H,A,0.29,-0.67,2.145,,67.83,OOH,-1.22267,0.0495842,0.00476637,0.995594 beta-lactamase_0_L160E,beta-lactamase_0_160,TEM-1,beta-lactamase_0,P62593,0.995597,NO,160,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.977,-3.906,2.929,,0.022,,B,0.55,-0.6,0.68,,44.41,BHA,-0.936,0.0500837,0.00193775,0.995597 beta-lactamase_625_A148G,beta-lactamase_625_148,TEM-1,beta-lactamase_625,P62593,0.995597,NO,148,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.757,-2.542,0.785,,0.379,H,A,0.46,-0.55,1.359,,72.73,PHH,-1.40167,0.213352,0.00547053,0.995597 beta-lactamase_625_T147L,beta-lactamase_625_147,TEM-1,beta-lactamase_625,P62593,0.995597,NO,147,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.149,-3.242,2.093,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.213352,0.00226017,0.995597 beta-lactamase_2500_T138R,beta-lactamase_2500_138,TEM-1,beta-lactamase_2500,P62593,0.9956,NO,138,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.506,-2.605,0.099,,0.662,H,A,0.22,-0.03,30.445,30.445,73.78,HPP,-1.81233,0.361275,0.00487868,0.9956 kka2_1:8_D82Q,kka2_1:8_82,Kka2,kka2_1:8,P00552,0.995601,NO,82,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.946,-2.981,1.035,,0.341,E,b,0.29,0.52,7.463,,63.64,HAH,-1.98,0.100394,0.00637516,0.995601 kka2_1:8_D82Q,kka2_1:8_82,Kka2,kka2_1:8,P00552,0.995601,NO,82,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.946,-2.981,1.035,,0.341,E,b,0.29,0.52,7.463,,63.64,HAH,-1.98,0.100394,0.00637516,0.995601 beta-lactamase_39_G154R,beta-lactamase_39_154,TEM-1,beta-lactamase_39,P62593,0.995603,NO,154,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.823,-3.969,3.146,,0.54,T,l,0.29,-0.56,1.151,,64.69,HOA,-1.635,0.0495842,0.00180205,0.995603 beta-lactamase_156_T147A,beta-lactamase_156_147,TEM-1,beta-lactamase_156,P62593,0.995604,NO,147,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.149,-2.982,1.833,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.111618,0.00226017,0.995604 beta-lactamase_2500_A200S,beta-lactamase_2500_200,TEM-1,beta-lactamase_2500,P62593,0.995606,NO,200,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.878,-2.183,0.305,,0.757,H,A,0.46,-0.19,0.436,,77.62,HHP,-2.001,0.361275,0.0060056,0.995606 kka2_1:2_D5D,kka2_1:2_5,Kka2,kka2_1:2,P00552,0.995607,NO,5,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.306,-1.306,,,,,,,,,,71.59,PAO,-1.784,0.295029,0.00222864,0.995607 beta-lactamase_156_N134R,beta-lactamase_156_134,TEM-1,beta-lactamase_156,P62593,0.995608,NO,134,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-0.879,-3.446,2.567,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.111618,0.000644786,0.995608 beta-lactamase_2500_V29H,beta-lactamase_2500_29,TEM-1,beta-lactamase_2500,P62593,0.995608,NO,29,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-2.856,-4.571,1.715,,0.733,H,A,0.44,-0.78,1.931,,93.01,HHB,-2.24733,0.361275,0.00318969,0.995608 beta-lactamase_A211L,beta-lactamase_211,TEM-1,beta-lactamase,P62593,0.995609,NO,211,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.896,-3.595,1.699,5.54662,0.369,T,A,0.52,-0.69,2.061,,77.62,AHA,-1.94633,0.221079,0.00648183,0.995609 beta-lactamase_156_R162S,beta-lactamase_156_162,TEM-1,beta-lactamase_156,P62593,0.99561,NO,162,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.016,-3.456,2.44,,0.124,S,B,1.2,-0.37,7.444,,64.69,ABH,-1.25,0.111618,0.000561334,0.99561 beta-lactamase_2500_E195G,beta-lactamase_2500_195,TEM-1,beta-lactamase_2500,P62593,0.995613,NO,195,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.186,-2.611,0.425,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.361275,0.00496565,0.995613 beta-lactamase_625_R273C,beta-lactamase_625_273,TEM-1,beta-lactamase_625,P62593,0.995614,NO,273,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.314,-5.09,2.776,,0.564,H,A,1.2,1.57,1.455,,73.78,ABP,-1.841,0.213352,0.0077952,0.995614 beta-lactamase_625_T198A,beta-lactamase_625_198,TEM-1,beta-lactamase_625,P62593,0.995617,NO,198,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.168,-2.502,0.334,,0.489,,B,0.22,-0.13,0.37,,73.78,HPH,-1.98767,0.213352,0.004311,0.995617 beta-lactamase_39_K190N,beta-lactamase_39_190,TEM-1,beta-lactamase_39,P62593,0.995619,NO,190,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.994,-2.601,0.607,,0.371,H,A,2.34,0.16,1.513,,77.62,BBH,-1.64167,0.0495842,0.00574527,0.995619 beta-lactamase_39_G236A,beta-lactamase_39_236,TEM-1,beta-lactamase_39,P62593,0.99562,NO,236,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.784,-2.29,1.506,,0.241,,b,0.29,-0.59,1.883,,64.69,HOO,-1.025,0.0495842,0.00162372,0.99562 beta-lactamase_39_L49W,beta-lactamase_39_49,TEM-1,beta-lactamase_39,P62593,0.99562,NO,49,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.897,-5.315,3.418,,0.131,T,A,0.55,0.04,13.838,13.838,64.69,AHP,-1.99233,0.0495842,0.00401477,0.99562 beta-lactamase_2500_N173K,beta-lactamase_2500_173,TEM-1,beta-lactamase_2500,P62593,0.995622,NO,173,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-2.663,-2.711,0.048,,1.044,T,l,0.61,1.25,1.88,,77.62,OPA,-1.46633,0.361275,0.0033769,0.995622 beta-lactamase_625_L248I,beta-lactamase_625_248,TEM-1,beta-lactamase_625,P62593,0.995624,NO,248,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.213352,0.00428493,0.995624 PSD95pdz3_Q374W,PSD95pdz3_374,PSD95pdz3,PSD95pdz3,P31016,0.995629,NO,374,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-1.699,-4.779,3.08,5.38825,,,,,17.3289,,,,APH,-1.47,0.0758425,0.000372298,0.995629 beta-lactamase_39_F64V,beta-lactamase_39_64,TEM-1,beta-lactamase_39,P62593,0.99563,NO,64,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-0.841,-3.304,2.463,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.0495842,0.000947691,0.99563 beta-lactamase_39_P25T,beta-lactamase_39_25,TEM-1,beta-lactamase_39,P62593,0.995631,NO,25,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.526,-3.483,1.957,,0.624,H,A,0.52,0.14,1.157,,73.08,BOA,-2.15367,0.0495842,0.00347571,0.995631 kka2_1:8_L94V,kka2_1:8_94,Kka2,kka2_1:8,P00552,0.995634,NO,94,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.618,-2.483,0.865,,0.058,E,B,1.59,-0.52,2.197,,56.06,HHO,-1.612,0.100394,0.00520888,0.995634 kka2_1:8_L94V,kka2_1:8_94,Kka2,kka2_1:8,P00552,0.995634,NO,94,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.618,-2.483,0.865,,0.058,E,B,1.59,-0.52,2.197,,56.06,HHO,-1.612,0.100394,0.00520888,0.995634 beta-lactamase_R41R,beta-lactamase_41,TEM-1,beta-lactamase,P62593,0.995636,NO,41,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-0.942,-0.942,,5.69185,0.321,E,B,0.91,-0.07,4.357,,65.03,HBH,-1.30267,0.221079,0.00123327,0.995636 kka2_1:2_E63A,kka2_1:2_63,Kka2,kka2_1:2,P00552,0.995643,NO,63,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-0.762,-3.106,2.344,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.295029,0.00118399,0.995643 beta-lactamase_156_H24A,beta-lactamase_156_24,TEM-1,beta-lactamase_156,P62593,0.995644,NO,24,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-2.481,-2.265,-0.216,,,,,,,2.708,,93.01,OBO,-2.0035,0.111618,0.00238894,0.995644 beta-lactamase_2500_H94Q,beta-lactamase_2500_94,TEM-1,beta-lactamase_2500,P62593,0.995649,NO,94,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-2.5,-3.155,0.655,,0.776,,B,0.17,1.24,1.176,,77.62,HBH,-1.872,0.361275,0.00389226,0.995649 kka2_1:2_E169H,kka2_1:2_169,Kka2,kka2_1:2,P00552,0.995651,NO,169,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.996,-4.724,2.728,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.295029,0.00730086,0.995651 PSD95pdz3_V386N,PSD95pdz3_386,PSD95pdz3,PSD95pdz3,P31016,0.995654,NO,386,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.465,-3.805,2.34,5.18836,,,,,17.5429,,,,PHP,-1.463,0.0758425,0.000184509,0.995654 beta-lactamase_156_L136I,beta-lactamase_156_136,TEM-1,beta-lactamase_156,P62593,0.995656,NO,136,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.232,-1.874,0.642,,,H,A,0.55,-0.34,1.04,,48.95,HHH,-1.088,0.111618,0.00442304,0.995656 beta-lactamase_625_I206A,beta-lactamase_625_206,TEM-1,beta-lactamase_625,P62593,0.995656,NO,206,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-2.429,-2.387,-0.042,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.213352,0.00528934,0.995656 beta-lactamase_39_G236H,beta-lactamase_39_236,TEM-1,beta-lactamase_39,P62593,0.995658,NO,236,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.784,-4.704,3.92,,0.241,,b,0.29,-0.59,1.883,,64.69,HOO,-1.025,0.0495842,0.00162372,0.995658 beta-lactamase_39_T178V,beta-lactamase_39_178,TEM-1,beta-lactamase_39,P62593,0.995658,NO,178,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-0.791,-3.079,2.288,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.0495842,0.000684366,0.995658 beta-lactamase_156_P172C,beta-lactamase_156_172,TEM-1,beta-lactamase_156,P62593,0.995665,NO,172,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.998,-4.977,3.979,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.111618,0.00312594,0.995665 beta-lactamase_625_W163G,beta-lactamase_625_163,TEM-1,beta-lactamase_625,P62593,0.995668,NO,163,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-1.843,-2.648,0.805,,0.467,,B,0.47,-0.5,5.019,,63.99,BHA,-1.269,0.213352,0.00418955,0.995668 kka2_1:1_E231E,kka2_1:1_231,Kka2,kka2_1:1,P00552,0.995668,NO,231,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.002,-2.002,,,0.503,H,A,1.04,-0.23,25.629,25.629,63.26,AAH,-2.06267,0.520039,0.00732383,0.995668 beta-lactamase_39_A278Y,beta-lactamase_39_278,TEM-1,beta-lactamase_39,P62593,0.995669,NO,278,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.0495842,0.0310297,0.995669 beta-lactamase_R7H,beta-lactamase_7,TEM-1,beta-lactamase,P62593,0.995669,NO,7,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.683,-4.345,2.662,,,,,,,2.44,,67.13,HBH,-1.96267,0.221079,0.00211375,0.995669 beta-lactamase_2500_Q88M,beta-lactamase_2500_88,TEM-1,beta-lactamase_2500,P62593,0.995671,NO,88,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.086,-3.418,1.332,,0.807,,B,0.64,2.03,1.84,,77.62,APH,-1.53433,0.361275,0.00504167,0.995671 beta-lactamase_39_V82F,beta-lactamase_39_82,TEM-1,beta-lactamase_39,P62593,0.995674,NO,82,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.325,-3.991,2.666,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.0495842,0.00397046,0.995674 beta-lactamase_625_T198H,beta-lactamase_625_198,TEM-1,beta-lactamase_625,P62593,0.995674,NO,198,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.168,-3.211,1.043,,0.489,,B,0.22,-0.13,0.37,,73.78,HPH,-1.98767,0.213352,0.004311,0.995674 beta-lactamase_0_D48N,beta-lactamase_0_48,TEM-1,beta-lactamase_0,P62593,0.995675,NO,48,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.101,-3.389,2.288,,0.189,E,B,0.75,0.21,17.825,17.825,50.35,HAH,-1.62467,0.0500837,0.0027273,0.995675 beta-lactamase_156_E175F,beta-lactamase_156_175,TEM-1,beta-lactamase_156,P62593,0.995675,NO,175,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.336,-4.36,2.024,,0.551,,A,1.04,1.05,2.334,,77.62,AAB,-1.31233,0.111618,0.00482205,0.995675 beta-lactamase_156_L111G,beta-lactamase_156_111,TEM-1,beta-lactamase_156,P62593,0.995676,NO,111,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.76,-3.666,1.906,,0.328,T,A,0.55,0.93,2.26,,64.34,BHP,-1.884,0.111618,0.00480671,0.995676 beta-lactamase_156_H156S,beta-lactamase_156_156,TEM-1,beta-lactamase_156,P62593,0.995677,NO,156,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-3.156,-2.584,-0.572,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.111618,0.00468596,0.995677 beta-lactamase_L136L,beta-lactamase_136,TEM-1,beta-lactamase,P62593,0.995677,NO,136,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.232,-1.232,,5.31114,,H,A,2.89,-0.34,1.539,,48.95,HHH,-1.088,0.221079,0.00442304,0.995677 beta-lactamase_156_V82W,beta-lactamase_156_82,TEM-1,beta-lactamase_156,P62593,0.99568,NO,82,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.325,-5.421,4.096,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.111618,0.00397046,0.99568 beta-lactamase_39_K32R,beta-lactamase_39_32,TEM-1,beta-lactamase_39,P62593,0.99568,NO,32,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.984,-2.38,0.396,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.0495842,0.00401283,0.99568 beta-lactamase_39_A40Q,beta-lactamase_39_40,TEM-1,beta-lactamase_39,P62593,0.995682,NO,40,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.402,-4.1,2.698,,0.155,S,B,0.46,0.21,0.783,,73.78,OHB,-1.40267,0.0495842,0.00490026,0.995682 beta-lactamase_625_S221L,beta-lactamase_625_221,TEM-1,beta-lactamase_625,P62593,0.995691,NO,221,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.754,-3.35,1.596,,0.624,H,A,0.27,-0.2,1.495,,74.48,BPH,-1.59967,0.213352,0.0046094,0.995691 beta-lactamase_39_W163G,beta-lactamase_39_163,TEM-1,beta-lactamase_39,P62593,0.995693,NO,163,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-1.843,-2.648,0.805,,0.467,,B,0.47,-0.5,15.095,15.095,63.99,BHA,-1.269,0.0495842,0.00418955,0.995693 Pab1_N162A,Pab1_162,Pab1,Pab1,P04147,0.995694,NO,162,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-2.313,-2.548,0.235,,0.681,T,A,,1.12,,,,APO,-1.532,0.175299,0.0030719,0.995694 kka2_1:2_Q100R,kka2_1:2_100,Kka2,kka2_1:2,P00552,0.995695,NO,100,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.77,-2.202,-0.568,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.295029,0.0066405,0.995695 beta-lactamase_39_L223S,beta-lactamase_39_223,TEM-1,beta-lactamase_39,P62593,0.995699,NO,223,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.055,-3.587,2.532,,0.27,,B,0.55,0.09,1.511,,74.48,HHO,-1.35033,0.0495842,0.00372793,0.995699 beta-lactamase_156_N274S,beta-lactamase_156_274,TEM-1,beta-lactamase_156,P62593,0.995701,NO,274,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.111618,0.0110418,0.995701 beta-lactamase_2500_A84T,beta-lactamase_2500_84,TEM-1,beta-lactamase_2500,P62593,0.995701,NO,84,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.651,-2.88,1.229,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.361275,0.00503822,0.995701 beta-lactamase_2500_Q86H,beta-lactamase_2500_86,TEM-1,beta-lactamase_2500,P62593,0.995701,NO,86,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.4,-4.718,2.318,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.361275,0.00450027,0.995701 beta-lactamase_625_Q276Y,beta-lactamase_625_276,TEM-1,beta-lactamase_625,P62593,0.995702,NO,276,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.213352,0.0191712,0.995702 beta-lactamase_625_N98K,beta-lactamase_625_98,TEM-1,beta-lactamase_625,P62593,0.995705,NO,98,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-2.973,-2.653,-0.32,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.213352,0.00505389,0.995705 Pab1_N192D,Pab1_192,Pab1,Pab1,P04147,0.995705,NO,192,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-1.079,-2.836,1.757,,0.619,T,l,,2.28,,,,HPO,-1.231,0.175299,0.000273498,0.995705 beta-lactamase_156_G52K,beta-lactamase_156_52,TEM-1,beta-lactamase_156,P62593,0.995709,NO,52,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.149,-3.631,2.482,,0.299,,l,0.29,-0.04,1.179,,64.69,POB,-1.66267,0.111618,0.00340138,0.995709 beta-lactamase_39_N98F,beta-lactamase_39_98,TEM-1,beta-lactamase_39,P62593,0.995713,NO,98,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-2.973,-3.271,0.298,,0.963,G,A,0.61,1.35,14.853,14.853,77.62,PPA,-2.07867,0.0495842,0.00505389,0.995713 beta-lactamase_39_V31T,beta-lactamase_39_31,TEM-1,beta-lactamase_39,P62593,0.995718,NO,31,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.822,-2.805,0.983,,,H,A,0.44,-0.46,2.885,,73.78,BHB,-2.03767,0.0495842,0.00478065,0.995718 beta-lactamase_156_K144R,beta-lactamase_156_144,TEM-1,beta-lactamase_156,P62593,0.995722,NO,144,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-2.388,-3.055,0.667,,0.863,H,A,2.34,1.27,2.073,,77.62,OBA,-1.904,0.111618,0.00481141,0.995722 beta-lactamase_625_L191Y,beta-lactamase_625_191,TEM-1,beta-lactamase_625,P62593,0.995725,NO,191,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.087,-3.913,2.826,,,H,A,0.55,0.09,1.908,,63.29,BHH,-1.445,0.213352,0.00263549,0.995725 beta-lactamase_39_K286C,beta-lactamase_39_286,TEM-1,beta-lactamase_39,P62593,0.995726,NO,286,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.0495842,,0.995726 beta-lactamase_39_R202S,beta-lactamase_39_202,TEM-1,beta-lactamase_39,P62593,0.995729,NO,202,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.292,-2.609,1.317,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.0495842,0.00321899,0.995729 beta-lactamase_156_L167T,beta-lactamase_156_167,TEM-1,beta-lactamase_156,P62593,0.995731,NO,167,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.138,-3.44,2.302,,0.015,G,A,0.55,-0.63,0.4,,64.69,AHP,-1.30767,0.111618,0.00303566,0.995731 beta-lactamase_156_Q276R,beta-lactamase_156_276,TEM-1,beta-lactamase_156,P62593,0.995732,NO,276,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.111618,0.0191712,0.995732 beta-lactamase_39_G265C,beta-lactamase_39_265,TEM-1,beta-lactamase_39,P62593,0.995734,NO,265,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.0495842,0.00811926,0.995734 PSD95pdz3_Y392A,PSD95pdz3_392,PSD95pdz3,PSD95pdz3,P31016,0.995737,NO,392,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-1.437,-2.984,1.547,5.20337,,,,,11.725,,,,PHB,-1.51733,0.0758425,0.000935211,0.995737 beta-lactamase_39_P224V,beta-lactamase_39_224,TEM-1,beta-lactamase_39,P62593,0.99574,NO,224,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.893,-3.599,2.706,,0.383,,B,0.52,-0.3,3.169,,74.48,HOH,-1.26433,0.0495842,0.00189564,0.99574 beta-lactamase_625_A182M,beta-lactamase_625_182,TEM-1,beta-lactamase_625,P62593,0.99574,NO,182,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.777,-4.709,2.932,,0.136,H,A,0.46,-0.66,16.784,16.784,93.01,OHH,-1.27367,0.213352,0.00559099,0.99574 Pab1_T159T,Pab1_159,Pab1,Pab1,P04147,0.995743,NO,159,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.445,-1.445,,,,,,,,2.531,,79.03,HPA,-1.19467,0.175299,0.00133849,0.995743 beta-lactamase_625_H24L,beta-lactamase_625_24,TEM-1,beta-lactamase_625,P62593,0.995744,NO,24,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-2.481,-3.404,0.923,,,,,,,2.708,,93.01,OBO,-2.0035,0.213352,0.00238894,0.995744 beta-lactamase_625_G216I,beta-lactamase_625_216,TEM-1,beta-lactamase_625,P62593,0.995745,NO,216,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.477,-4.183,2.706,,0.437,I,A,0.29,-0.58,1.718,,74.48,HOO,-1.68067,0.213352,0.00639568,0.995745 beta-lactamase_39_A247T,beta-lactamase_39_247,TEM-1,beta-lactamase_39,P62593,0.995746,NO,247,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.0495842,0.00611275,0.995746 beta-lactamase_2500_N173C,beta-lactamase_2500_173,TEM-1,beta-lactamase_2500,P62593,0.995749,NO,173,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-2.663,-5.092,2.429,,1.044,T,l,0.61,1.25,1.88,,77.62,OPA,-1.46633,0.361275,0.0033769,0.995749 kka2_1:8_R177R,kka2_1:8_177,Kka2,kka2_1:8,P00552,0.995751,NO,177,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.282,-2.282,,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.100394,0.00768224,0.995751 kka2_1:8_R177R,kka2_1:8_177,Kka2,kka2_1:8,P00552,0.995751,NO,177,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.282,-2.282,,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.100394,0.00768224,0.995751 beta-lactamase_625_E279I,beta-lactamase_625_279,TEM-1,beta-lactamase_625,P62593,0.995753,NO,279,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.213352,0.0192826,0.995753 beta-lactamase_156_S51T,beta-lactamase_156_51,TEM-1,beta-lactamase_156,P62593,0.995757,NO,51,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.526,-1.846,0.32,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.111618,0.00504821,0.995757 beta-lactamase_156_N173T,beta-lactamase_156_173,TEM-1,beta-lactamase_156,P62593,0.995762,NO,173,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-2.663,-3.589,0.926,,1.044,T,l,0.61,1.25,3.718,,77.62,OPA,-1.46633,0.111618,0.0033769,0.995762 beta-lactamase_156_T193W,beta-lactamase_156_193,TEM-1,beta-lactamase_156,P62593,0.995764,NO,193,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.914,-5.211,3.297,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.111618,0.00482669,0.995764 beta-lactamase_39_G265D,beta-lactamase_39_265,TEM-1,beta-lactamase_39,P62593,0.995766,NO,265,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.0495842,0.00811926,0.995766 beta-lactamase_E61E,beta-lactamase_61,TEM-1,beta-lactamase,P62593,0.995766,NO,61,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.115,-2.115,,6.29701,0.775,T,a,0.52,1.29,1.975,,77.62,OAA,-1.92567,0.221079,0.00440955,0.995766 beta-lactamase_625_N152G,beta-lactamase_625_152,TEM-1,beta-lactamase_625,P62593,0.995767,NO,152,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-2.757,-2.26,-0.497,,0.863,H,A,0.61,0.92,2.061,,77.62,BPH,-2.97,0.213352,0.00471429,0.995767 kka2_1:4_P167Q,kka2_1:4_167,Kka2,kka2_1:4,P00552,0.995769,NO,167,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-2.403,-4.147,1.744,,0.18,H,A,0.52,0.75,3.6,,64.39,HOH,-2.26633,0.168804,0.00543203,0.995769 beta-lactamase_156_G265W,beta-lactamase_156_265,TEM-1,beta-lactamase_156,P62593,0.99577,NO,265,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.111618,0.00811926,0.99577 beta-lactamase_156_S96A,beta-lactamase_156_96,TEM-1,beta-lactamase_156,P62593,0.995772,NO,96,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.27,-2.75,0.48,,0.368,,b,0.27,0.39,2.838,,73.78,HPP,-2.019,0.111618,0.00551835,0.995772 beta-lactamase_39_G90S,beta-lactamase_39_90,TEM-1,beta-lactamase_39,P62593,0.995772,NO,90,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-2.091,-2.198,0.107,,0.598,T,A,0.29,0.32,30.794,30.794,77.62,HOB,-1.52633,0.0495842,0.00490273,0.995772 beta-lactamase_156_E210Q,beta-lactamase_156_210,TEM-1,beta-lactamase_156,P62593,0.995773,NO,210,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.319,-2.627,0.308,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.111618,0.00663582,0.995773 beta-lactamase_39_A200T,beta-lactamase_39_200,TEM-1,beta-lactamase_39,P62593,0.995782,NO,200,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.878,-2.493,0.615,,0.757,H,A,0.46,-0.19,1.54,,77.62,HHP,-2.001,0.0495842,0.0060056,0.995782 beta-lactamase_39_A182L,beta-lactamase_39_182,TEM-1,beta-lactamase_39,P62593,0.995783,NO,182,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.777,-3.486,1.709,,0.136,H,A,0.46,-0.66,2.598,,93.01,OHH,-1.27367,0.0495842,0.00559099,0.995783 beta-lactamase_39_Y95F,beta-lactamase_39_95,TEM-1,beta-lactamase_39,P62593,0.995783,NO,95,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-1.715,-2.096,0.381,,0.122,,b,0.21,-0.37,2.341,,77.62,BHP,-2.16167,0.0495842,0.00479449,0.995783 beta-lactamase_625_E61N,beta-lactamase_625_61,TEM-1,beta-lactamase_625,P62593,0.995784,NO,61,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.115,-2.373,0.258,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.213352,0.00440955,0.995784 kka2_1:8_K138N,kka2_1:8_138,Kka2,kka2_1:8,P00552,0.995784,NO,138,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-2.5,-3.757,1.257,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.100394,0.00628542,0.995784 kka2_1:8_K138N,kka2_1:8_138,Kka2,kka2_1:8,P00552,0.995784,NO,138,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-2.5,-3.757,1.257,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.100394,0.00628542,0.995784 beta-lactamase_K53V,beta-lactamase_53,TEM-1,beta-lactamase,P62593,0.995785,NO,53,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-2.313,-3.678,1.365,5.93654,0.589,,B,1.82,1.15,19.72,19.72,77.62,OBH,-2.1,0.221079,0.00383383,0.995785 beta-lactamase_39_A278C,beta-lactamase_39_278,TEM-1,beta-lactamase_39,P62593,0.995787,NO,278,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.0495842,0.0310297,0.995787 beta-lactamase_156_A183M,beta-lactamase_156_183,TEM-1,beta-lactamase_156,P62593,0.995791,NO,183,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.231,-4.59,3.359,,0.155,H,A,0.46,-0.91,23.859,23.859,77.62,HHH,-1.53367,0.111618,0.00296631,0.995791 beta-lactamase_39_R176H,beta-lactamase_39_176,TEM-1,beta-lactamase_39,P62593,0.995795,NO,176,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-0.863,-4.23,3.367,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.0495842,0.00105554,0.995795 beta-lactamase_156_A278F,beta-lactamase_156_278,TEM-1,beta-lactamase_156,P62593,0.995797,NO,278,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.111618,0.0310297,0.995797 beta-lactamase_156_D83N,beta-lactamase_156_83,TEM-1,beta-lactamase_156,P62593,0.995799,NO,83,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.066,-3.355,2.289,,0.354,H,A,0.75,0.22,1.281,,48.95,HAH,-1.34733,0.111618,0.00205968,0.995799 beta-lactamase_39_T126M,beta-lactamase_39_126,TEM-1,beta-lactamase_39,P62593,0.995799,NO,126,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.122,-4.659,3.537,,0.05,H,A,0.22,-0.05,0.586,,44.41,HPH,-1.60467,0.0495842,0.00244552,0.995799 beta-lactamase_2500_T193A,beta-lactamase_2500_193,TEM-1,beta-lactamase_2500,P62593,0.995803,NO,193,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.914,-2.618,0.704,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.361275,0.00482669,0.995803 beta-lactamase_39_G281Y,beta-lactamase_39_281,TEM-1,beta-lactamase_39,P62593,0.995806,NO,281,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.0495842,0.0406482,0.995806 beta-lactamase_625_S122V,beta-lactamase_625_122,TEM-1,beta-lactamase_625,P62593,0.995806,NO,122,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.406,-2.967,0.561,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.213352,0.00497825,0.995806 beta-lactamase_39_Q37S,beta-lactamase_39_37,TEM-1,beta-lactamase_39,P62593,0.995811,NO,37,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.134,-2.839,0.705,,0.613,H,A,0.64,1.98,22.282,22.282,73.08,APH,-2.06967,0.0495842,0.00425833,0.995811 beta-lactamase_156_I140H,beta-lactamase_156_140,TEM-1,beta-lactamase_156,P62593,0.995817,NO,140,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.733,-4.991,3.258,,0.128,H,A,0.48,0.41,1.16,,73.08,PHO,-1.48733,0.111618,0.00597777,0.995817 beta-lactamase_39_N168W,beta-lactamase_39_168,TEM-1,beta-lactamase_39,P62593,0.995817,NO,168,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-1.029,-5.48,4.451,,0.113,G,A,0.61,-0.4,0.822,,44.41,HPA,-1.13233,0.0495842,0.00288667,0.995817 beta-lactamase_625_T27Q,beta-lactamase_625_27,TEM-1,beta-lactamase_625,P62593,0.995819,NO,27,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.905,-3.929,2.024,,0.007,H,A,0.22,-0.37,3.72,,93.01,APH,-1.97933,0.213352,0.00306559,0.995819 beta-lactamase_39_R220Y,beta-lactamase_39_220,TEM-1,beta-lactamase_39,P62593,0.99582,NO,220,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-0.942,-4.188,3.246,,0.295,I,A,1.2,-0.76,1.596,,74.48,HBP,-1.33633,0.0495842,0.00232421,0.99582 beta-lactamase_2500_L196A,beta-lactamase_2500_196,TEM-1,beta-lactamase_2500,P62593,0.995826,NO,196,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-2.478,-1.974,-0.504,,0.518,S,A,0.55,1.35,7.897,,77.62,AHH,-1.839,0.361275,0.00512144,0.995826 beta-lactamase_39_E61H,beta-lactamase_39_61,TEM-1,beta-lactamase_39,P62593,0.995826,NO,61,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.115,-4.518,2.403,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.0495842,0.00440955,0.995826 beta-lactamase_2500_S57Q,beta-lactamase_2500_57,TEM-1,beta-lactamase_2500,P62593,0.995827,NO,57,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.918,-3.995,2.077,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.361275,0.00492804,0.995827 beta-lactamase_156_H156T,beta-lactamase_156_156,TEM-1,beta-lactamase_156,P62593,0.995831,NO,156,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-3.156,-2.632,-0.524,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.111618,0.00468596,0.995831 beta-lactamase_39_D231E,beta-lactamase_39_231,TEM-1,beta-lactamase_39,P62593,0.995831,NO,231,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.816,-2.232,1.416,,,E,B,0.75,-1.06,0.462,,65.38,HAB,-0.994,0.0495842,0.00107395,0.995831 beta-lactamase_39_L192S,beta-lactamase_39_192,TEM-1,beta-lactamase_39,P62593,0.995831,NO,192,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.254,-3.616,2.362,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.0495842,0.00558728,0.995831 beta-lactamase_156_D33Y,beta-lactamase_156_33,TEM-1,beta-lactamase_156,P62593,0.995838,NO,33,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.321,-4.331,2.01,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.111618,0.00435556,0.995838 beta-lactamase_625_V157T,beta-lactamase_625_157,TEM-1,beta-lactamase_625,P62593,0.995839,NO,157,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.751,-2.302,0.551,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.213352,0.00506849,0.995839 beta-lactamase_156_A124C,beta-lactamase_156_124,TEM-1,beta-lactamase_156,P62593,0.995841,NO,124,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.181,-4.594,3.413,,,H,A,0.46,-0.9,2.027,,64.34,HHH,-1.152,0.111618,0.00481399,0.995841 beta-lactamase_625_S221V,beta-lactamase_625_221,TEM-1,beta-lactamase_625,P62593,0.995841,NO,221,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.754,-3.416,1.662,,0.624,H,A,0.27,-0.2,1.495,,74.48,BPH,-1.59967,0.213352,0.0046094,0.995841 beta-lactamase_625_D207N,beta-lactamase_625_207,TEM-1,beta-lactamase_625,P62593,0.995843,NO,207,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.064,-2.966,0.902,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.213352,0.00592942,0.995843 beta-lactamase_625_P255E,beta-lactamase_625_255,TEM-1,beta-lactamase_625,P62593,0.995845,NO,255,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.213352,0.00499612,0.995845 beta-lactamase_156_E238L,beta-lactamase_156_238,TEM-1,beta-lactamase_156,P62593,0.995847,NO,238,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.111618,0.00743256,0.995847 beta-lactamase_2500_R202S,beta-lactamase_2500_202,TEM-1,beta-lactamase_2500,P62593,0.995848,NO,202,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.292,-2.609,1.317,,0.188,H,A,1.2,0.62,3.734,,77.62,PBP,-1.54767,0.361275,0.00321899,0.995848 beta-lactamase_39_K144H,beta-lactamase_39_144,TEM-1,beta-lactamase_39,P62593,0.995851,NO,144,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-2.388,-3.395,1.007,,0.863,H,A,2.34,1.27,14.556,14.556,77.62,OBA,-1.904,0.0495842,0.00481141,0.995851 beta-lactamase_625_M153V,beta-lactamase_625_153,TEM-1,beta-lactamase_625,P62593,0.995852,NO,153,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-3.193,-2.524,-0.669,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.213352,0.00509109,0.995852 beta-lactamase_2500_Q97G,beta-lactamase_2500_97,TEM-1,beta-lactamase_2500,P62593,0.995853,NO,97,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.072,-2.827,0.755,,0.823,G,A,0.64,2.42,1.157,,77.62,PPP,-2.43833,0.361275,0.0045116,0.995853 beta-lactamase_156_L219K,beta-lactamase_156_219,TEM-1,beta-lactamase_156,P62593,0.995854,NO,219,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.313,-3.875,2.562,,,I,A,0.55,-0.51,2.321,,74.48,HHB,-1.21533,0.111618,0.00664345,0.995854 beta-lactamase_39_V31M,beta-lactamase_39_31,TEM-1,beta-lactamase_39,P62593,0.995855,NO,31,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.822,-3.184,1.362,,,H,A,0.44,-0.46,2.885,,73.78,BHB,-2.03767,0.0495842,0.00478065,0.995855 beta-lactamase_39_V117E,beta-lactamase_39_117,TEM-1,beta-lactamase_39,P62593,0.99586,NO,117,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.53,-3.909,2.379,,,H,A,0.44,-0.34,1.182,,65.03,PHB,-1.741,0.0495842,0.00467906,0.99586 beta-lactamase_39_S256I,beta-lactamase_39_256,TEM-1,beta-lactamase_39,P62593,0.995866,NO,256,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.621,-3.676,2.055,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.0495842,0.00710634,0.995866 kka2_1:4_A71H,kka2_1:4_71,Kka2,kka2_1:4,P00552,0.995866,NO,71,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.824,-3.209,1.385,,0.553,H,A,0.46,0.08,5.76,,64.39,HHP,-1.74033,0.168804,0.00727707,0.995866 beta-lactamase_0_T187P,beta-lactamase_0_187,TEM-1,beta-lactamase_0,P62593,0.995868,NO,187,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.401,-3.906,2.505,,0.007,H,A,0.22,-1.19,3.259,,67.48,PPH,-1.69633,0.0500837,0.00491782,0.995868 beta-lactamase_156_Y95A,beta-lactamase_156_95,TEM-1,beta-lactamase_156,P62593,0.995869,NO,95,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-1.715,-3.364,1.649,,0.122,,b,0.21,-0.37,2.341,,77.62,BHP,-2.16167,0.111618,0.00479449,0.995869 beta-lactamase_156_P250R,beta-lactamase_156_250,TEM-1,beta-lactamase_156,P62593,0.995871,NO,250,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.111618,0.00550899,0.995871 beta-lactamase_39_K53L,beta-lactamase_39_53,TEM-1,beta-lactamase_39,P62593,0.995873,NO,53,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-2.313,-2.678,0.365,,0.589,,B,2.34,1.15,15.633,15.633,77.62,OBH,-2.1,0.0495842,0.00383383,0.995873 beta-lactamase_156_L111D,beta-lactamase_156_111,TEM-1,beta-lactamase_156,P62593,0.995879,NO,111,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.76,-3.995,2.235,,0.328,T,A,0.55,0.93,2.26,,64.34,BHP,-1.884,0.111618,0.00480671,0.995879 beta-lactamase_156_Q97S,beta-lactamase_156_97,TEM-1,beta-lactamase_156,P62593,0.995879,NO,97,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.072,-3.388,1.316,,0.823,G,A,0.64,2.42,4.457,,77.62,PPP,-2.43833,0.111618,0.0045116,0.995879 beta-lactamase_625_V82T,beta-lactamase_625_82,TEM-1,beta-lactamase_625,P62593,0.995886,NO,82,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.325,-3.392,2.067,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.213352,0.00397046,0.995886 beta-lactamase_156_L196T,beta-lactamase_156_196,TEM-1,beta-lactamase_156,P62593,0.995888,NO,196,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-2.478,-2.588,0.11,,0.518,S,A,0.55,1.35,7.897,,77.62,AHH,-1.839,0.111618,0.00512144,0.995888 beta-lactamase_39_T264D,beta-lactamase_39_264,TEM-1,beta-lactamase_39,P62593,0.99589,NO,264,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.0495842,0.0119399,0.99589 beta-lactamase_2500_N50S,beta-lactamase_2500_50,TEM-1,beta-lactamase_2500,P62593,0.995894,NO,50,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-2.979,-3.331,0.352,,0.912,T,A,0.61,1.24,1.581,,77.62,HPP,-2.134,0.361275,0.0047211,0.995894 beta-lactamase_39_T116S,beta-lactamase_39_116,TEM-1,beta-lactamase_39,P62593,0.995895,NO,116,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.28,-1.932,0.652,,0.115,E,B,0.22,-0.12,1.133,,67.48,HPH,-1.39967,0.0495842,0.00336175,0.995895 beta-lactamase_0_K286A,beta-lactamase_0_286,TEM-1,beta-lactamase_0,P62593,0.995896,NO,286,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.0500837,,0.995896 beta-lactamase_625_A148V,beta-lactamase_625_148,TEM-1,beta-lactamase_625,P62593,0.995904,NO,148,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.757,-3.631,1.874,,0.379,H,A,0.46,-0.55,1.359,,72.73,PHH,-1.40167,0.213352,0.00547053,0.995904 beta-lactamase_625_D174Q,beta-lactamase_625_174,TEM-1,beta-lactamase_625,P62593,0.995908,NO,174,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.738,-3.674,2.936,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.213352,0.00125633,0.995908 beta-lactamase_2500_L55I,beta-lactamase_2500_55,TEM-1,beta-lactamase_2500,P62593,0.995909,NO,55,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.86,-2.434,0.574,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.361275,0.00403741,0.995909 beta-lactamase_156_L28V,beta-lactamase_156_28,TEM-1,beta-lactamase_156,P62593,0.995915,NO,28,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.579,-1.979,0.4,,0.277,H,A,0.55,-0.16,3.262,,93.01,PHH,-2.11333,0.111618,0.00359321,0.995915 beta-lactamase_156_S80M,beta-lactamase_156_80,TEM-1,beta-lactamase_156,P62593,0.99592,NO,80,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.029,-4.671,2.642,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.111618,0.00565569,0.99592 beta-lactamase_39_G265L,beta-lactamase_39_265,TEM-1,beta-lactamase_39,P62593,0.99592,NO,265,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.0495842,0.00811926,0.99592 beta-lactamase_39_R239P,beta-lactamase_39_239,TEM-1,beta-lactamase_39,P62593,0.995921,NO,239,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.0495842,0.00213852,0.995921 beta-lactamase_2500_D207R,beta-lactamase_2500_207,TEM-1,beta-lactamase_2500,P62593,0.995922,NO,207,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.064,-2.841,0.777,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.361275,0.00592942,0.995922 kka2_1:1_L158L,kka2_1:1_158,Kka2,kka2_1:1,P00552,0.995924,NO,158,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.947,-1.947,,,0.095,.,B,0.55,0.77,7.588,,63.64,AHA,-1.25333,0.520039,0.00529068,0.995924 gb1_V247Q,gb1_247,gb1,gb1,P06654,0.995926,NO,247,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.711,-3.947,2.236,,,,,,,0.805,,44.87,HHA,-1.485,0.177985,0.00435373,0.995926 beta-lactamase_625_A268H,beta-lactamase_625_268,TEM-1,beta-lactamase_625,P62593,0.995929,NO,268,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.213352,0.0102525,0.995929 beta-lactamase_39_S51P,beta-lactamase_39_51,TEM-1,beta-lactamase_39,P62593,0.995935,NO,51,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.526,-3.858,2.332,,0.496,T,A,0.27,0.26,2.964,,72.73,PPO,-1.88467,0.0495842,0.00504821,0.995935 beta-lactamase_625_V260C,beta-lactamase_625_260,TEM-1,beta-lactamase_625,P62593,0.995936,NO,260,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.213352,0.00471757,0.995936 beta-lactamase_2500_A148D,beta-lactamase_2500_148,TEM-1,beta-lactamase_2500,P62593,0.995937,NO,148,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.757,-2.341,0.584,,0.379,H,A,0.46,-0.55,2.117,,72.73,PHH,-1.40167,0.361275,0.00547053,0.995937 beta-lactamase_2500_L199P,beta-lactamase_2500_199,TEM-1,beta-lactamase_2500,P62593,0.995946,NO,199,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-2.942,-2.099,-0.843,,0.832,H,A,0.55,0.42,15.504,15.504,77.62,PHH,-2.32933,0.361275,0.0048649,0.995946 beta-lactamase_A148A,beta-lactamase_148,TEM-1,beta-lactamase,P62593,0.995951,NO,148,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.757,-1.757,,5.28111,0.379,H,A,0.52,-0.55,2.117,,72.73,PHH,-1.40167,0.221079,0.00547053,0.995951 beta-lactamase_G39S,beta-lactamase_39,TEM-1,beta-lactamase,P62593,0.995951,NO,39,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.864,-2.342,0.478,5.35574,0.701,T,L,0.23,0.47,29.926,29.926,77.62,HOH,-1.53633,0.221079,0.00487611,0.995951 beta-lactamase_Q37W,beta-lactamase_37,TEM-1,beta-lactamase,P62593,0.995951,NO,37,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.134,-3.439,1.305,5.69153,0.613,H,A,0.12,1.98,1.318,,73.08,APH,-2.06967,0.221079,0.00425833,0.995951 beta-lactamase_R189W,beta-lactamase_189,TEM-1,beta-lactamase,P62593,0.995951,NO,189,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.844,-5.37,3.526,5.74877,0.278,H,A,0.68,1.01,1.512,,72.73,HBB,-1.668,0.221079,0.0050699,0.995951 beta-lactamase_S51E,beta-lactamase_51,TEM-1,beta-lactamase,P62593,0.995951,NO,51,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.526,-3.428,1.902,5.06164,0.496,T,A,0.25,0.26,1.699,,72.73,PPO,-1.88467,0.221079,0.00504821,0.995951 beta-lactamase_T267Q,beta-lactamase_267,TEM-1,beta-lactamase,P62593,0.995951,NO,267,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.308,-3.09,0.782,5.28263,0.54,,B,0.69,-0.14,0.374,,73.78,HPH,-1.9,0.221079,0.0102128,0.995951 beta-lactamase_156_T187C,beta-lactamase_156_187,TEM-1,beta-lactamase_156,P62593,0.995952,NO,187,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.401,-4.859,3.458,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.111618,0.00491782,0.995952 beta-lactamase_39_D212A,beta-lactamase_39_212,TEM-1,beta-lactamase_39,P62593,0.995954,NO,212,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.624,-2.64,1.016,,0.037,,b,0.75,-0.58,10.748,10.748,74.48,HAB,-1.77667,0.0495842,0.00644302,0.995954 beta-lactamase_39_A77H,beta-lactamase_39_77,TEM-1,beta-lactamase_39,P62593,0.99596,NO,77,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.234,-3.165,1.931,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.0495842,0.00282362,0.99596 beta-lactamase_39_G142C,beta-lactamase_39_142,TEM-1,beta-lactamase_39,P62593,0.995966,NO,142,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.707,-5.05,4.343,,0.034,,p,0.29,-0.64,1.947,,64.69,OOO,-0.834,0.0495842,0.00060149,0.995966 beta-lactamase_39_L73P,beta-lactamase_39_73,TEM-1,beta-lactamase_39,P62593,0.995969,NO,73,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.507,-2.751,1.244,,,H,A,0.55,-0.64,2.09,,67.83,HHH,-1.487,0.0495842,0.00488983,0.995969 beta-lactamase_625_S51M,beta-lactamase_625_51,TEM-1,beta-lactamase_625,P62593,0.995972,NO,51,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.526,-4.705,3.179,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.213352,0.00504821,0.995972 beta-lactamase_156_S256H,beta-lactamase_156_256,TEM-1,beta-lactamase_156,P62593,0.99598,NO,256,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.111618,0.00710634,0.99598 beta-lactamase_625_G216A,beta-lactamase_625_216,TEM-1,beta-lactamase_625,P62593,0.995982,NO,216,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.477,-2.596,1.119,,0.437,I,A,0.29,-0.58,1.718,,74.48,HOO,-1.68067,0.213352,0.00639568,0.995982 beta-lactamase_A84V,beta-lactamase_84,TEM-1,beta-lactamase,P62593,0.995984,NO,84,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.651,-2.943,1.292,5.28927,0.65,T,A,0.52,0.96,1.863,,68.18,AHO,-1.24267,0.221079,0.00503822,0.995984 beta-lactamase_2500_E102V,beta-lactamase_2500_102,TEM-1,beta-lactamase_2500,P62593,0.995989,NO,102,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.118,-3.638,1.52,,0.722,S,B,1.04,1.82,1.336,,73.08,HAH,-1.581,0.361275,0.00486633,0.995989 beta-lactamase_2500_Q37G,beta-lactamase_2500_37,TEM-1,beta-lactamase_2500,P62593,0.99599,NO,37,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.134,-3.507,1.373,,0.613,H,A,0.64,1.98,1.318,,73.08,APH,-2.06967,0.361275,0.00425833,0.99599 beta-lactamase_625_S221C,beta-lactamase_625_221,TEM-1,beta-lactamase_625,P62593,0.995994,NO,221,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.754,-3.097,1.343,,0.624,H,A,0.27,-0.2,1.495,,74.48,BPH,-1.59967,0.213352,0.0046094,0.995994 beta-lactamase_156_G85L,beta-lactamase_156_85,TEM-1,beta-lactamase_156,P62593,0.995997,NO,85,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.011,-3.755,2.744,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.111618,0.00252173,0.995997 beta-lactamase_625_A182N,beta-lactamase_625_182,TEM-1,beta-lactamase_625,P62593,0.996,NO,182,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.777,-3.015,1.238,,0.136,H,A,0.46,-0.66,16.784,16.784,93.01,OHH,-1.27367,0.213352,0.00559099,0.996 beta-lactamase_625_A77E,beta-lactamase_625_77,TEM-1,beta-lactamase_625,P62593,0.996,NO,77,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.234,-3.61,2.376,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.213352,0.00282362,0.996 beta-lactamase_625_T193V,beta-lactamase_625_193,TEM-1,beta-lactamase_625,P62593,0.996001,NO,193,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.914,-2.673,0.759,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.213352,0.00482669,0.996001 beta-lactamase_625_L196T,beta-lactamase_625_196,TEM-1,beta-lactamase_625,P62593,0.996005,NO,196,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-2.478,-2.588,0.11,,0.518,S,A,0.55,1.35,12.152,12.152,77.62,AHH,-1.839,0.213352,0.00512144,0.996005 beta-lactamase_2500_E195Q,beta-lactamase_2500_195,TEM-1,beta-lactamase_2500,P62593,0.996006,NO,195,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.186,-2.527,0.341,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.361275,0.00496565,0.996006 beta-lactamase_625_D271P,beta-lactamase_625_271,TEM-1,beta-lactamase_625,P62593,0.996006,NO,271,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.213352,0.00752082,0.996006 beta-lactamase_625_D36L,beta-lactamase_625_36,TEM-1,beta-lactamase_625,P62593,0.996006,NO,36,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.732,-3.628,0.896,,0.555,H,A,0.75,1.17,2.26,,77.62,AAP,-1.91167,0.213352,0.00476483,0.996006 beta-lactamase_625_D99L,beta-lactamase_625_99,TEM-1,beta-lactamase_625,P62593,0.996006,NO,99,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.191,-3.588,2.397,,0.402,G,A,0.75,0.36,1.318,,64.69,PAH,-1.794,0.213352,0.00305446,0.996006 beta-lactamase_2500_K109S,beta-lactamase_2500_109,TEM-1,beta-lactamase_2500,P62593,0.996012,NO,109,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.734,-2.861,1.127,,0.787,G,A,2.34,2.21,0.998,,72.73,ABB,-1.63333,0.361275,0.00462493,0.996012 beta-lactamase_156_L196Y,beta-lactamase_156_196,TEM-1,beta-lactamase_156,P62593,0.996017,NO,196,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-2.478,-4.286,1.808,,0.518,S,A,0.55,1.35,7.897,,77.62,AHH,-1.839,0.111618,0.00512144,0.996017 beta-lactamase_156_P250A,beta-lactamase_156_250,TEM-1,beta-lactamase_156,P62593,0.996023,NO,250,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.111618,0.00550899,0.996023 beta-lactamase_156_G141L,beta-lactamase_156_141,TEM-1,beta-lactamase_156,P62593,0.996027,NO,141,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.828,-3.844,3.016,,0.575,T,l,0.29,-0.28,0.198,,64.69,HOO,-1.08933,0.111618,0.0012419,0.996027 beta-lactamase_39_E279W,beta-lactamase_39_279,TEM-1,beta-lactamase_39,P62593,0.996027,NO,279,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.0495842,0.0192826,0.996027 beta-lactamase_625_G194M,beta-lactamase_625_194,TEM-1,beta-lactamase_625,P62593,0.996035,NO,194,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.396,-4.893,3.497,,0.276,S,b,0.29,0.36,3.593,,67.83,POA,-1.832,0.213352,0.00392163,0.996035 beta-lactamase_39_K30N,beta-lactamase_39_30,TEM-1,beta-lactamase_39,P62593,0.996037,NO,30,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-2.307,-2.865,0.558,,0.142,H,A,2.34,-0.65,6.717,,93.01,HBH,-2.32833,0.0495842,0.00448593,0.996037 PSD95pdz3_I341F,PSD95pdz3_341,PSD95pdz3,PSD95pdz3,P31016,0.996037,NO,341,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.63,-3.299,1.669,5.73946,,,,,10.3187,,,,HHH,-1.50033,0.0758425,0.000824087,0.996037 beta-lactamase_39_N173D,beta-lactamase_39_173,TEM-1,beta-lactamase_39,P62593,0.99604,NO,173,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-2.663,-2.368,-0.295,,1.044,T,l,0.61,1.25,1.426,,77.62,OPA,-1.46633,0.0495842,0.0033769,0.99604 beta-lactamase_2500_A84I,beta-lactamase_2500_84,TEM-1,beta-lactamase_2500,P62593,0.996042,NO,84,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.651,-3.932,2.281,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.361275,0.00503822,0.996042 beta-lactamase_39_P250C,beta-lactamase_39_250,TEM-1,beta-lactamase_39,P62593,0.996043,NO,250,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.0495842,0.00550899,0.996043 kka2_1:1_G234G,kka2_1:1_234,Kka2,kka2_1:1,P00552,0.996048,NO,234,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-2.9,-2.9,,,0.494,H,A,0.29,-0.29,1.753,,71.59,OOA,-1.86767,0.520039,0.00984449,0.996048 beta-lactamase_39_L47S,beta-lactamase_39_47,TEM-1,beta-lactamase_39,P62593,0.996049,NO,47,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.876,-3.642,1.766,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.0495842,0.00439844,0.996049 beta-lactamase_156_S80L,beta-lactamase_156_80,TEM-1,beta-lactamase_156,P62593,0.99605,NO,80,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.029,-2.857,0.828,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.111618,0.00565569,0.99605 beta-lactamase_S221A,beta-lactamase_221,TEM-1,beta-lactamase,P62593,0.996051,NO,221,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.754,-1.332,-0.422,5.77407,0.624,H,A,0.74,-0.2,0.383,,74.48,BPH,-1.59967,0.221079,0.0046094,0.996051 beta-lactamase_156_K286V,beta-lactamase_156_286,TEM-1,beta-lactamase_156,P62593,0.996057,NO,286,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.111618,,0.996057 beta-lactamase_P253A,beta-lactamase_253,TEM-1,beta-lactamase,P62593,0.996057,NO,253,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-2.253,-1.977,-0.276,5.24842,0.308,,B,0.73,-0.46,2.293,,73.08,BOP,-2.10633,0.221079,0.00786358,0.996057 beta-lactamase_156_Q276Y,beta-lactamase_156_276,TEM-1,beta-lactamase_156,P62593,0.996061,NO,276,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.111618,0.0191712,0.996061 beta-lactamase_39_N50H,beta-lactamase_39_50,TEM-1,beta-lactamase_39,P62593,0.996062,NO,50,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-2.979,-3.33,0.351,,0.912,T,A,0.61,1.24,10.736,,77.62,HPP,-2.134,0.0495842,0.0047211,0.996062 beta-lactamase_2500_V29I,beta-lactamase_2500_29,TEM-1,beta-lactamase_2500,P62593,0.996063,NO,29,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-2.856,-3.928,1.072,,0.733,H,A,0.44,-0.78,1.931,,93.01,HHB,-2.24733,0.361275,0.00318969,0.996063 beta-lactamase_625_I261V,beta-lactamase_625_261,TEM-1,beta-lactamase_625,P62593,0.996063,NO,261,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.213352,0.0123091,0.996063 kka2_1:8_A224T,kka2_1:8_224,Kka2,kka2_1:8,P00552,0.996067,NO,224,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.977,-1.898,0.921,,,H,A,0.46,-1.26,0.357,,63.64,HHP,-1.41033,0.100394,0.00352047,0.996067 kka2_1:8_A224T,kka2_1:8_224,Kka2,kka2_1:8,P00552,0.996067,NO,224,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.977,-1.898,0.921,,,H,A,0.46,-1.26,0.357,,63.64,HHP,-1.41033,0.100394,0.00352047,0.996067 beta-lactamase_0_T264M,beta-lactamase_0_264,TEM-1,beta-lactamase_0,P62593,0.996069,NO,264,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.0500837,0.0119399,0.996069 beta-lactamase_M67N,beta-lactamase_67,TEM-1,beta-lactamase,P62593,0.996073,NO,67,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-2.231,-2.235,0.004,4.9618,0.006,G,P,1.07,-0.81,1.463,,65.03,HHP,-1.502,0.221079,0.00409753,0.996073 beta-lactamase_625_H156S,beta-lactamase_625_156,TEM-1,beta-lactamase_625,P62593,0.996077,NO,156,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-3.156,-2.584,-0.572,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.213352,0.00468596,0.996077 beta-lactamase_2500_G226K,beta-lactamase_2500_226,TEM-1,beta-lactamase_2500,P62593,0.996078,NO,226,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.461,-2.859,1.398,,0.701,T,l,0.29,-0.25,5.086,,74.48,HOH,-1.42933,0.361275,0.00665294,0.996078 beta-lactamase_156_K32L,beta-lactamase_156_32,TEM-1,beta-lactamase_156,P62593,0.996079,NO,32,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.984,-2.812,0.828,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.111618,0.00401283,0.996079 beta-lactamase_39_K32L,beta-lactamase_39_32,TEM-1,beta-lactamase_39,P62593,0.99608,NO,32,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.984,-2.812,0.828,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.0495842,0.00401283,0.99608 beta-lactamase_625_R63L,beta-lactamase_625_63,TEM-1,beta-lactamase_625,P62593,0.996082,NO,63,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-0.943,-2.476,1.533,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.213352,0.00126938,0.996082 beta-lactamase_625_E145W,beta-lactamase_625_145,TEM-1,beta-lactamase_625,P62593,0.996086,NO,145,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.357,-5.352,2.995,,0.545,H,A,1.04,0.79,2.64,,77.62,BAH,-2.069,0.213352,0.00553285,0.996086 beta-lactamase_156_F58S,beta-lactamase_156_58,TEM-1,beta-lactamase_156,P62593,0.996088,NO,58,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-2.914,-2.895,-0.019,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.111618,0.00523369,0.996088 beta-lactamase_156_G216L,beta-lactamase_156_216,TEM-1,beta-lactamase_156,P62593,0.996093,NO,216,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.477,-3.78,2.303,,0.437,I,A,0.29,-0.58,12.464,12.464,74.48,HOO,-1.68067,0.111618,0.00639568,0.996093 beta-lactamase_156_C75T,beta-lactamase_156_75,TEM-1,beta-lactamase_156,P62593,0.996094,NO,75,C,T,CT,Special,Polar,5.07,5.6,0.53,149,121,119,-2,108.5,116.1,7.6,-1.245,-3.423,2.178,,,H,A,0.46,-0.87,0.876,,50,HOO,-1.24333,0.111618,0.0034616,0.996094 beta-lactamase_156_E46C,beta-lactamase_156_46,TEM-1,beta-lactamase_156,P62593,0.996095,NO,46,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.94,-3.249,1.309,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.111618,0.00427568,0.996095 beta-lactamase_39_S256C,beta-lactamase_39_256,TEM-1,beta-lactamase_39,P62593,0.9961,NO,256,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.0495842,0.00710634,0.9961 beta-lactamase_156_R273Q,beta-lactamase_156_273,TEM-1,beta-lactamase_156,P62593,0.996103,NO,273,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.314,-2.364,0.05,,0.564,H,A,1.2,1.57,20.248,20.248,73.78,ABP,-1.841,0.111618,0.0077952,0.996103 beta-lactamase_156_T269M,beta-lactamase_156_269,TEM-1,beta-lactamase_156,P62593,0.996103,NO,269,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.111618,0.00950944,0.996103 beta-lactamase_39_A132T,beta-lactamase_39_132,TEM-1,beta-lactamase_39,P62593,0.996112,NO,132,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.9,-3.22,2.32,,,H,A,0.46,-0.93,8.408,,64.69,PHH,-1.138,0.0495842,0.000962524,0.996112 beta-lactamase_625_T269D,beta-lactamase_625_269,TEM-1,beta-lactamase_625,P62593,0.996115,NO,269,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.156,-3.518,1.362,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.213352,0.00950944,0.996115 beta-lactamase_39_K32I,beta-lactamase_39_32,TEM-1,beta-lactamase_39,P62593,0.996116,NO,32,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.984,-2.835,0.851,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.0495842,0.00401283,0.996116 beta-lactamase_625_P25E,beta-lactamase_625_25,TEM-1,beta-lactamase_625,P62593,0.996119,NO,25,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.526,-2.543,1.017,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.213352,0.00347571,0.996119 beta-lactamase_39_L49D,beta-lactamase_39_49,TEM-1,beta-lactamase_39,P62593,0.996123,NO,49,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.897,-3.778,1.881,,0.131,T,A,0.55,0.04,13.838,13.838,64.69,AHP,-1.99233,0.0495842,0.00401477,0.996123 beta-lactamase_39_L79Q,beta-lactamase_39_79,TEM-1,beta-lactamase_39,P62593,0.996124,NO,79,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.842,-4.087,3.245,,0.007,H,A,0.55,-0.16,0.823,,50.35,HHP,-1.44333,0.0495842,0.000947397,0.996124 beta-lactamase_A84L,beta-lactamase_84,TEM-1,beta-lactamase,P62593,0.996125,NO,84,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.651,-3.508,1.857,5.28927,0.65,T,A,0.52,0.96,1.863,,68.18,AHO,-1.24267,0.221079,0.00503822,0.996125 beta-lactamase_156_R257V,beta-lactamase_156_257,TEM-1,beta-lactamase_156,P62593,0.996126,NO,257,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.533,-4.11,2.577,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.111618,0.00756629,0.996126 beta-lactamase_156_L55D,beta-lactamase_156_55,TEM-1,beta-lactamase_156,P62593,0.996127,NO,55,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.86,-4.094,2.234,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.111618,0.00403741,0.996127 beta-lactamase_625_Y103N,beta-lactamase_625_103,TEM-1,beta-lactamase_625,P62593,0.996128,NO,103,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-1.33,-2.825,1.495,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.213352,0.00443048,0.996128 beta-lactamase_0_L135Q,beta-lactamase_0_135,TEM-1,beta-lactamase_0,P62593,0.996131,NO,135,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.002,-4.162,3.16,,0.117,H,A,0.55,-0.58,0.705,,43.71,PHH,-1.03767,0.0500837,0.00244423,0.996131 beta-lactamase_625_A40C,beta-lactamase_625_40,TEM-1,beta-lactamase_625,P62593,0.996135,NO,40,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.402,-4.779,3.377,,0.155,S,B,0.46,0.21,1.357,,73.78,OHB,-1.40267,0.213352,0.00490026,0.996135 beta-lactamase_39_P172W,beta-lactamase_39_172,TEM-1,beta-lactamase_39,P62593,0.996142,NO,172,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.998,-5.528,4.53,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.0495842,0.00312594,0.996142 Pab1_G193R,Pab1_193,Pab1,Pab1,P04147,0.996142,NO,193,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.414,-3.746,2.332,,,,,,,,,,POP,-1.55733,0.175299,0.0014922,0.996142 beta-lactamase_156_P217M,beta-lactamase_156_217,TEM-1,beta-lactamase_156,P62593,0.996144,NO,217,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-2.062,-4.835,2.773,,0.496,I,A,0.52,-0.33,2.303,,74.48,OOH,-1.64333,0.111618,0.00463211,0.996144 PSD95pdz3_A378V,PSD95pdz3_378,PSD95pdz3,PSD95pdz3,P31016,0.996147,NO,378,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.307,-2.76,1.453,4.86582,,,,,14.576,,,,HHH,-1.509,0.0758425,0.000313169,0.996147 beta-lactamase_625_P25V,beta-lactamase_625_25,TEM-1,beta-lactamase_625,P62593,0.996148,NO,25,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.526,-3.565,2.039,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.213352,0.00347571,0.996148 beta-lactamase_R238K,beta-lactamase_238,TEM-1,beta-lactamase,P62593,0.996151,NO,238,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.002,-3.419,1.417,5.87663,0.564,T,L,0.45,1.09,4.195,,72.73,ABO,-1.62633,0.221079,0.00743256,0.996151 PSD95pdz3_K380L,PSD95pdz3_380,PSD95pdz3,PSD95pdz3,P31016,0.996155,NO,380,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.416,-3.04,1.624,5.87979,,,,,19.6722,,,,HBP,-1.391,0.0758425,0.000281399,0.996155 beta-lactamase_625_H24W,beta-lactamase_625_24,TEM-1,beta-lactamase_625,P62593,0.996156,NO,24,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-2.481,-5.305,2.824,,,,,,,2.708,,93.01,OBO,-2.0035,0.213352,0.00238894,0.996156 beta-lactamase_156_K144I,beta-lactamase_156_144,TEM-1,beta-lactamase_156,P62593,0.996159,NO,144,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-2.388,-4.014,1.626,,0.863,H,A,2.34,1.27,2.073,,77.62,OBA,-1.904,0.111618,0.00481141,0.996159 beta-lactamase_156_N134T,beta-lactamase_156_134,TEM-1,beta-lactamase_156,P62593,0.996159,NO,134,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-0.879,-3.245,2.366,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.111618,0.000644786,0.996159 beta-lactamase_156_L160A,beta-lactamase_156_160,TEM-1,beta-lactamase_156,P62593,0.996161,NO,160,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.977,-3.094,2.117,,0.022,,B,0.55,-0.6,1.095,,44.41,BHA,-0.936,0.111618,0.00193775,0.996161 beta-lactamase_156_N274C,beta-lactamase_156_274,TEM-1,beta-lactamase_156,P62593,0.996162,NO,274,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.111618,0.0110418,0.996162 beta-lactamase_2500_Q37F,beta-lactamase_2500_37,TEM-1,beta-lactamase_2500,P62593,0.996162,NO,37,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.134,-4.314,2.18,,0.613,H,A,0.64,1.98,1.318,,73.08,APH,-2.06967,0.361275,0.00425833,0.996162 beta-lactamase_39_A230G,beta-lactamase_39_230,TEM-1,beta-lactamase_39,P62593,0.996162,NO,230,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.154,-1.479,0.325,,0.01,E,B,0.46,-1.17,1.171,,50,HHA,-1.079,0.0495842,0.00516841,0.996162 beta-lactamase_625_I93Y,beta-lactamase_625_93,TEM-1,beta-lactamase_625,P62593,0.996163,NO,93,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.401,-4.112,2.711,,0.128,E,B,0.48,0.44,1.524,,67.83,BHB,-1.873,0.213352,0.00527066,0.996163 beta-lactamase_39_I54A,beta-lactamase_39_54,TEM-1,beta-lactamase_39,P62593,0.996164,NO,54,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-2.838,-2.597,-0.241,,0.669,E,B,0.48,-0.14,1.349,,73.78,BHH,-2.337,0.0495842,0.00403589,0.996164 beta-lactamase_625_A182S,beta-lactamase_625_182,TEM-1,beta-lactamase_625,P62593,0.996165,NO,182,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.777,-2.825,1.048,,0.136,H,A,0.46,-0.66,16.784,16.784,93.01,OHH,-1.27367,0.213352,0.00559099,0.996165 beta-lactamase_K109T,beta-lactamase_109,TEM-1,beta-lactamase,P62593,0.996173,NO,109,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.734,-2.559,0.825,6.05842,0.787,G,A,1.82,2.21,21.623,21.623,72.73,ABB,-1.63333,0.221079,0.00462493,0.996173 beta-lactamase_L89L,beta-lactamase_89,TEM-1,beta-lactamase,P62593,0.996177,NO,89,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.096,-1.096,,5.41092,0.168,T,A,1.75,0.63,1.599,,64.34,PHO,-1.75767,0.221079,0.00207068,0.996177 beta-lactamase_156_G265S,beta-lactamase_156_265,TEM-1,beta-lactamase_156,P62593,0.996179,NO,265,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.111618,0.00811926,0.996179 Pab1_S165S,Pab1_165,Pab1,Pab1,P04147,0.996184,NO,165,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.146,-1.146,,,0.12,,a,,0.11,,,,BPB,-1.56867,0.175299,0.000307838,0.996184 beta-lactamase_156_P60T,beta-lactamase_156_60,TEM-1,beta-lactamase_156,P62593,0.996186,NO,60,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-2.469,-3.483,1.014,,0.256,T,A,0.52,-0.56,2.947,,77.62,BOA,-1.97633,0.111618,0.00521318,0.996186 beta-lactamase_625_V117T,beta-lactamase_625_117,TEM-1,beta-lactamase_625,P62593,0.996187,NO,117,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.53,-3.486,1.956,,,H,A,0.44,-0.34,1.23,,65.03,PHB,-1.741,0.213352,0.00467906,0.996187 beta-lactamase_E61K,beta-lactamase_61,TEM-1,beta-lactamase,P62593,0.996189,NO,61,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.115,-3.46,1.345,6.29701,0.775,T,a,0.52,1.29,1.975,,77.62,OAA,-1.92567,0.221079,0.00440955,0.996189 kka2_1:2_V242V,kka2_1:2_242,Kka2,kka2_1:2,P00552,0.996189,NO,242,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-2.687,-2.687,,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.295029,0.0102575,0.996189 beta-lactamase_625_V260A,beta-lactamase_625_260,TEM-1,beta-lactamase_625,P62593,0.996191,NO,260,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.213352,0.00471757,0.996191 beta-lactamase_156_K53I,beta-lactamase_156_53,TEM-1,beta-lactamase_156,P62593,0.996192,NO,53,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-2.313,-4.015,1.702,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.111618,0.00383383,0.996192 beta-lactamase_156_P105E,beta-lactamase_156_105,TEM-1,beta-lactamase_156,P62593,0.996195,NO,105,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.813,-3.437,2.624,,0.226,T,A,0.52,0.8,1.154,,63.29,POH,-1.01533,0.111618,0.0011981,0.996195 kka2_1:4_A150G,kka2_1:4_150,Kka2,kka2_1:4,P00552,0.996199,NO,150,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.949,-2.199,1.25,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.168804,0.0045009,0.996199 beta-lactamase_39_L223E,beta-lactamase_39_223,TEM-1,beta-lactamase_39,P62593,0.996207,NO,223,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.055,-3.868,2.813,,0.27,,B,0.55,0.09,1.511,,74.48,HHO,-1.35033,0.0495842,0.00372793,0.996207 hsp90_Q582A,hsp90_582,hsp90,hsp90,P02829,0.996208,NO,582,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-3.278,-2.456,0,4.91603,0.453,S,B,,0.67,,,,OPH,-3.249,0.368192,0.000222939,0.996208 beta-lactamase_156_A282G,beta-lactamase_156_282,TEM-1,beta-lactamase_156,P62593,0.996211,NO,282,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.111618,0.0449821,0.996211 beta-lactamase_156_A123E,beta-lactamase_156_123,TEM-1,beta-lactamase_156,P62593,0.996216,NO,123,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.834,-3.489,2.655,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.111618,0.0010157,0.996216 beta-lactamase_625_Q37A,beta-lactamase_625_37,TEM-1,beta-lactamase_625,P62593,0.996219,NO,37,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.134,-2.542,0.408,,0.613,H,A,0.64,1.98,1.318,,73.08,APH,-2.06967,0.213352,0.00425833,0.996219 kka2_1:4_N58C,kka2_1:4_58,Kka2,kka2_1:4,P00552,0.996225,NO,58,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-2.641,-2.921,0.28,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.168804,0.00793425,0.996225 beta-lactamase_156_L167A,beta-lactamase_156_167,TEM-1,beta-lactamase_156,P62593,0.99623,NO,167,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.138,-3.097,1.959,,0.015,G,A,0.55,-0.63,0.4,,64.69,AHP,-1.30767,0.111618,0.00303566,0.99623 beta-lactamase_39_N173T,beta-lactamase_39_173,TEM-1,beta-lactamase_39,P62593,0.996238,NO,173,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-2.663,-3.589,0.926,,1.044,T,l,0.61,1.25,1.426,,77.62,OPA,-1.46633,0.0495842,0.0033769,0.996238 beta-lactamase_625_L111V,beta-lactamase_625_111,TEM-1,beta-lactamase_625,P62593,0.996238,NO,111,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.76,-1.731,-0.029,,0.328,T,A,0.55,0.93,2.26,,64.34,BHP,-1.884,0.213352,0.00480671,0.996238 beta-lactamase_156_Q204D,beta-lactamase_156_204,TEM-1,beta-lactamase_156,P62593,0.996239,NO,204,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-1.382,-3.553,2.171,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.111618,0.00364106,0.996239 beta-lactamase_39_G114R,beta-lactamase_39_114,TEM-1,beta-lactamase_39,P62593,0.99624,NO,114,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.094,-2.891,1.797,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.0495842,0.00224919,0.99624 beta-lactamase_625_I258F,beta-lactamase_625_258,TEM-1,beta-lactamase_625,P62593,0.996246,NO,258,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.213352,0.007931,0.996246 beta-lactamase_39_R239A,beta-lactamase_39_239,TEM-1,beta-lactamase_39,P62593,0.996248,NO,239,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.0495842,0.00213852,0.996248 beta-lactamase_156_S96I,beta-lactamase_156_96,TEM-1,beta-lactamase_156,P62593,0.996249,NO,96,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.27,-3.225,0.955,,0.368,,b,0.27,0.39,2.838,,73.78,HPP,-2.019,0.111618,0.00551835,0.996249 kka2_1:8_G74L,kka2_1:8_74,Kka2,kka2_1:8,P00552,0.996249,NO,74,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.18,-3.872,2.692,,0.621,T,l,0.29,0.2,2.014,,64.39,POH,-1.91667,0.100394,0.00587035,0.996249 kka2_1:8_G74L,kka2_1:8_74,Kka2,kka2_1:8,P00552,0.996249,NO,74,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.18,-3.872,2.692,,0.621,T,l,0.29,0.2,2.014,,64.39,POH,-1.91667,0.100394,0.00587035,0.996249 beta-lactamase_156_P217R,beta-lactamase_156_217,TEM-1,beta-lactamase_156,P62593,0.99625,NO,217,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-2.062,-3.069,1.007,,0.496,I,A,0.52,-0.33,2.303,,74.48,OOH,-1.64333,0.111618,0.00463211,0.99625 beta-lactamase_39_A183Q,beta-lactamase_39_183,TEM-1,beta-lactamase_39,P62593,0.996255,NO,183,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.231,-3.932,2.701,,0.155,H,A,0.46,-0.91,1.237,,77.62,HHH,-1.53367,0.0495842,0.00296631,0.996255 beta-lactamase_156_S80T,beta-lactamase_156_80,TEM-1,beta-lactamase_156,P62593,0.996261,NO,80,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.029,-2.845,0.816,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.111618,0.00565569,0.996261 beta-lactamase_39_E56R,beta-lactamase_39_56,TEM-1,beta-lactamase_39,P62593,0.996264,NO,56,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.043,-3.679,1.636,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.0495842,0.00238534,0.996264 beta-lactamase_625_I125L,beta-lactamase_625_125,TEM-1,beta-lactamase_625,P62593,0.996266,NO,125,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.441,-1.939,0.498,,,H,A,0.48,-0.7,2.034,,63.29,HHP,-1.248,0.213352,0.00383964,0.996266 beta-lactamase_39_N134T,beta-lactamase_39_134,TEM-1,beta-lactamase_39,P62593,0.996271,NO,134,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-0.879,-3.245,2.366,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.0495842,0.000644786,0.996271 beta-lactamase_39_V78W,beta-lactamase_39_78,TEM-1,beta-lactamase_39,P62593,0.996271,NO,78,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.459,-5.345,3.886,,,H,A,0.44,-0.47,1.132,,63.64,HHH,-1.17833,0.0495842,0.00492501,0.996271 beta-lactamase_156_T264G,beta-lactamase_156_264,TEM-1,beta-lactamase_156,P62593,0.996275,NO,264,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.111618,0.0119399,0.996275 beta-lactamase_156_N134V,beta-lactamase_156_134,TEM-1,beta-lactamase_156,P62593,0.996276,NO,134,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-0.879,-3.751,2.872,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.111618,0.000644786,0.996276 beta-lactamase_156_G194Q,beta-lactamase_156_194,TEM-1,beta-lactamase_156,P62593,0.996282,NO,194,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.396,-3.925,2.529,,0.276,S,b,0.29,0.36,1.346,,67.83,POA,-1.832,0.111618,0.00392163,0.996282 beta-lactamase_156_S122Q,beta-lactamase_156_122,TEM-1,beta-lactamase_156,P62593,0.996284,NO,122,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.406,-2.914,0.508,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.111618,0.00497825,0.996284 kka2_1:1_A41A,kka2_1:1_41,Kka2,kka2_1:1,P00552,0.996286,NO,41,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.879,-1.879,,,0.184,.,B,0.46,-0.96,18.207,18.207,64.39,PHP,-2.477,0.520039,0.00543332,0.996286 beta-lactamase_39_A222F,beta-lactamase_39_222,TEM-1,beta-lactamase_39,P62593,0.996287,NO,222,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.103,-4.23,2.127,,0.233,H,A,0.46,-0.25,1.448,,77.62,PHH,-1.63733,0.0495842,0.00466094,0.996287 beta-lactamase_156_E102C,beta-lactamase_156_102,TEM-1,beta-lactamase_156,P62593,0.996292,NO,102,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.118,-5.064,2.946,,0.722,S,B,1.04,1.82,15.721,15.721,73.08,HAH,-1.581,0.111618,0.00486633,0.996292 beta-lactamase_39_S266E,beta-lactamase_39_266,TEM-1,beta-lactamase_39,P62593,0.996297,NO,266,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.0495842,0.0140785,0.996297 beta-lactamase_625_R202C,beta-lactamase_625_202,TEM-1,beta-lactamase_625,P62593,0.996298,NO,202,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.292,-5.047,3.755,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.213352,0.00321899,0.996298 kka2_1:4_P12G,kka2_1:4_12,Kka2,kka2_1:4,P00552,0.9963,NO,12,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.853,-3.308,2.455,,,,B,0.52,1.25,0.843,,48.11,POH,-1.80767,0.168804,0.00500011,0.9963 beta-lactamase_156_H94V,beta-lactamase_156_94,TEM-1,beta-lactamase_156,P62593,0.996303,NO,94,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-2.5,-2.751,0.251,,0.776,,B,0.17,1.24,11.583,11.583,77.62,HBH,-1.872,0.111618,0.00389226,0.996303 beta-lactamase_39_G76F,beta-lactamase_39_76,TEM-1,beta-lactamase_39,P62593,0.996303,NO,76,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.189,-4.264,3.075,,,H,A,0.29,-0.67,2.145,,67.83,OOH,-1.22267,0.0495842,0.00476637,0.996303 beta-lactamase_625_M270P,beta-lactamase_625_270,TEM-1,beta-lactamase_625,P62593,0.996303,NO,270,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.213352,0.00767762,0.996303 beta-lactamase_0_T158W,beta-lactamase_0_158,TEM-1,beta-lactamase_0,P62593,0.996311,NO,158,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.116,-5.268,4.152,,0.036,,B,0.22,-0.85,1.041,,69.58,HPB,-1.269,0.0500837,0.00341825,0.996311 beta-lactamase_625_S283G,beta-lactamase_625_283,TEM-1,beta-lactamase_625,P62593,0.996312,NO,283,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.213352,0.0429138,0.996312 PSD95pdz3_A382E,PSD95pdz3_382,PSD95pdz3,PSD95pdz3,P31016,0.996314,NO,382,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.307,-3.122,1.815,5.30282,,,,,22.472,,,,PHO,-1.24167,0.0758425,0.000249256,0.996314 beta-lactamase_39_T263L,beta-lactamase_39_263,TEM-1,beta-lactamase_39,P62593,0.996316,NO,263,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.0495842,0.0110582,0.996316 beta-lactamase_625_A34I,beta-lactamase_625_34,TEM-1,beta-lactamase_625,P62593,0.996316,NO,34,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.059,-2.06,0.001,,,H,A,0.46,-0.54,3.614,,73.78,AHA,-1.74967,0.213352,0.00407913,0.996316 beta-lactamase_156_G52S,beta-lactamase_156_52,TEM-1,beta-lactamase_156,P62593,0.996318,NO,52,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.149,-2.647,1.498,,0.299,,l,0.29,-0.04,1.179,,64.69,POB,-1.66267,0.111618,0.00340138,0.996318 beta-lactamase_39_G216A,beta-lactamase_39_216,TEM-1,beta-lactamase_39,P62593,0.996318,NO,216,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.477,-2.596,1.119,,0.437,I,A,0.29,-0.58,0.834,,74.48,HOO,-1.68067,0.0495842,0.00639568,0.996318 beta-lactamase_625_V78L,beta-lactamase_625_78,TEM-1,beta-lactamase_625,P62593,0.996318,NO,78,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.459,-1.714,0.255,,,H,A,0.44,-0.47,2.045,,63.64,HHH,-1.17833,0.213352,0.00492501,0.996318 beta-lactamase_39_A40T,beta-lactamase_39_40,TEM-1,beta-lactamase_39,P62593,0.996332,NO,40,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.402,-2.653,1.251,,0.155,S,B,0.46,0.21,0.783,,73.78,OHB,-1.40267,0.0495842,0.00490026,0.996332 kka2_1:2_A176F,kka2_1:2_176,Kka2,kka2_1:2,P00552,0.996333,NO,176,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.621,-4.399,2.778,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.295029,0.0083587,0.996333 Pab1_K180E,Pab1_180,Pab1,Pab1,P04147,0.996333,NO,180,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.945,-2.255,0.31,,,,,,,,,,HBA,-1.575,0.175299,0.00295933,0.996333 beta-lactamase_625_T269V,beta-lactamase_625_269,TEM-1,beta-lactamase_625,P62593,0.996334,NO,269,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.213352,0.00950944,0.996334 beta-lactamase_2500_E108N,beta-lactamase_2500_108,TEM-1,beta-lactamase_2500,P62593,0.996339,NO,108,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.46,-3.593,2.133,,0.572,G,A,1.04,1.87,1.147,,72.73,PAB,-1.437,0.361275,0.00413372,0.996339 beta-lactamase_156_N134D,beta-lactamase_156_134,TEM-1,beta-lactamase_156,P62593,0.99634,NO,134,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-0.879,-3.087,2.208,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.111618,0.000644786,0.99634 beta-lactamase_E56G,beta-lactamase_56,TEM-1,beta-lactamase,P62593,0.996343,NO,56,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.043,-2.304,0.261,5.65281,0.198,E,B,0.52,0.31,2.022,,72.73,HAP,-1.94033,0.221079,0.00238534,0.996343 beta-lactamase_156_R63K,beta-lactamase_156_63,TEM-1,beta-lactamase_156,P62593,0.99635,NO,63,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-0.943,-2.877,1.934,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.111618,0.00126938,0.99635 beta-lactamase_156_K286D,beta-lactamase_156_286,TEM-1,beta-lactamase_156,P62593,0.996352,NO,286,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.111618,,0.996352 beta-lactamase_156_R239S,beta-lactamase_156_239,TEM-1,beta-lactamase_156,P62593,0.996358,NO,239,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.111618,0.00213852,0.996358 beta-lactamase_D99Q,beta-lactamase_99,TEM-1,beta-lactamase,P62593,0.996361,NO,99,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.191,-2.836,1.645,5.66081,0.402,G,A,0.23,0.36,1.318,,64.69,PAH,-1.794,0.221079,0.00305446,0.996361 Pab1_E195I,Pab1_195,Pab1,Pab1,P04147,0.996362,NO,195,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.2,-3.881,2.681,,,,,,,,,,PAH,-1.72467,0.175299,0.000620107,0.996362 beta-lactamase_0_N130P,beta-lactamase_0_130,TEM-1,beta-lactamase_0,P62593,0.996364,NO,130,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-0.798,-3.88,3.082,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.0500837,0.000683376,0.996364 beta-lactamase_39_L111P,beta-lactamase_39_111,TEM-1,beta-lactamase_39,P62593,0.996366,NO,111,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.76,-4.076,2.316,,0.328,T,A,0.55,0.93,4.334,,64.34,BHP,-1.884,0.0495842,0.00480671,0.996366 beta-lactamase_625_S57L,beta-lactamase_625_57,TEM-1,beta-lactamase_625,P62593,0.99637,NO,57,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.918,-2.848,0.93,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.213352,0.00492804,0.99637 beta-lactamase_2500_E61A,beta-lactamase_2500_61,TEM-1,beta-lactamase_2500,P62593,0.996371,NO,61,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.115,-2.668,0.553,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.361275,0.00440955,0.996371 beta-lactamase_2500_K144Q,beta-lactamase_2500_144,TEM-1,beta-lactamase_2500,P62593,0.996375,NO,144,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-2.388,-2.378,-0.01,,0.863,H,A,2.34,1.27,0.515,,77.62,OBA,-1.904,0.361275,0.00481141,0.996375 beta-lactamase_39_R176N,beta-lactamase_39_176,TEM-1,beta-lactamase_39,P62593,0.996376,NO,176,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-0.863,-3.448,2.585,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.0495842,0.00105554,0.996376 beta-lactamase_39_V117C,beta-lactamase_39_117,TEM-1,beta-lactamase_39,P62593,0.996379,NO,117,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.53,-4.787,3.257,,,H,A,0.44,-0.34,1.182,,65.03,PHB,-1.741,0.0495842,0.00467906,0.996379 beta-lactamase_156_T139L,beta-lactamase_156_139,TEM-1,beta-lactamase_156,P62593,0.996399,NO,139,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.901,-3.419,1.518,,0.216,H,A,0.22,0.39,16.34,16.34,77.62,PPH,-2.04667,0.111618,0.00441837,0.996399 beta-lactamase_156_H110V,beta-lactamase_156_110,TEM-1,beta-lactamase_156,P62593,0.996401,NO,110,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-1.706,-3.735,2.029,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.111618,0.00441499,0.996401 beta-lactamase_39_G194T,beta-lactamase_39_194,TEM-1,beta-lactamase_39,P62593,0.996406,NO,194,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.396,-2.79,1.394,,0.276,S,b,0.29,0.36,4.852,,67.83,POA,-1.832,0.0495842,0.00392163,0.996406 beta-lactamase_2500_V29L,beta-lactamase_2500_29,TEM-1,beta-lactamase_2500,P62593,0.996407,NO,29,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-2.856,-3.547,0.691,,0.733,H,A,0.44,-0.78,1.931,,93.01,HHB,-2.24733,0.361275,0.00318969,0.996407 beta-lactamase_39_L120S,beta-lactamase_39_120,TEM-1,beta-lactamase_39,P62593,0.996408,NO,120,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.044,-3.66,2.616,,,H,A,0.55,-1.13,22.254,22.254,64.69,AHO,-1.13633,0.0495842,0.00143563,0.996408 beta-lactamase_L282V,beta-lactamase_282,TEM-1,beta-lactamase,P62593,0.996409,NO,282,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.586,-2.118,0.532,5.16743,0.007,H,A,1.07,0.34,31.31,31.31,63.99,PHH,-1.82367,0.221079,0.0449821,0.996409 beta-lactamase_156_L218P,beta-lactamase_156_218,TEM-1,beta-lactamase_156,P62593,0.996411,NO,218,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.391,-4.052,2.661,,,I,b,0.55,-0.53,17.202,17.202,74.48,OHH,-1.58867,0.111618,0.00618274,0.996411 beta-lactamase_156_H151N,beta-lactamase_156_151,TEM-1,beta-lactamase_156,P62593,0.996412,NO,151,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-2.96,-3.49,0.53,,0.594,H,A,0.17,0.1,1.401,,77.62,HBP,-2.34767,0.111618,0.00216946,0.996412 beta-lactamase_625_T198S,beta-lactamase_625_198,TEM-1,beta-lactamase_625,P62593,0.996412,NO,198,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.168,-1.471,-0.697,,0.489,,B,0.22,-0.13,0.37,,73.78,HPH,-1.98767,0.213352,0.004311,0.996412 beta-lactamase_156_K213P,beta-lactamase_156_213,TEM-1,beta-lactamase_156,P62593,0.996414,NO,213,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.81,-3.901,2.091,,0.67,,A,2.34,0.29,3.924,,67.83,ABH,-1.57767,0.111618,0.00610411,0.996414 beta-lactamase_156_R220N,beta-lactamase_156_220,TEM-1,beta-lactamase_156,P62593,0.996414,NO,220,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-0.942,-3.516,2.574,,0.295,I,A,1.2,-0.76,2.164,,74.48,HBP,-1.33633,0.111618,0.00232421,0.996414 beta-lactamase_156_A235Q,beta-lactamase_156_235,TEM-1,beta-lactamase_156,P62593,0.996421,NO,235,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.266,-4.018,2.752,,0.32,E,B,0.46,-0.86,1.344,,50,OHO,-0.89,0.111618,0.00493474,0.996421 beta-lactamase_625_K30V,beta-lactamase_625_30,TEM-1,beta-lactamase_625,P62593,0.996423,NO,30,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-2.307,-2.807,0.5,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.213352,0.00448593,0.996423 beta-lactamase_2500_I171T,beta-lactamase_2500_171,TEM-1,beta-lactamase_2500,P62593,0.996424,NO,171,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-2.431,-2.05,-0.381,,0.361,,B,0.48,0.53,1.66,,77.62,HHO,-1.55533,0.361275,0.00623355,0.996424 beta-lactamase_625_R41Q,beta-lactamase_625_41,TEM-1,beta-lactamase_625,P62593,0.996424,NO,41,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-0.942,-3.498,2.556,,0.321,E,B,1.2,-0.07,1.186,,65.03,HBH,-1.30267,0.213352,0.00123327,0.996424 beta-lactamase_625_N173E,beta-lactamase_625_173,TEM-1,beta-lactamase_625,P62593,0.996429,NO,173,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-2.663,-3.453,0.79,,1.044,T,l,0.61,1.25,1.426,,77.62,OPA,-1.46633,0.213352,0.0033769,0.996429 beta-lactamase_625_S256P,beta-lactamase_625_256,TEM-1,beta-lactamase_625,P62593,0.99643,NO,256,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.213352,0.00710634,0.99643 beta-lactamase_156_S221E,beta-lactamase_156_221,TEM-1,beta-lactamase_156,P62593,0.996432,NO,221,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.754,-3.442,1.688,,0.624,H,A,0.27,-0.2,17.729,17.729,74.48,BPH,-1.59967,0.111618,0.0046094,0.996432 kka2_1:4_S251S,kka2_1:4_251,Kka2,kka2_1:4,P00552,0.996432,NO,251,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.636,-2.636,,,0.712,H,A,0.77,-0.25,,,71.59,APP,-2.09367,0.168804,0.0138916,0.996432 kka2_1:2_D238D,kka2_1:2_238,Kka2,kka2_1:2,P00552,0.996433,NO,238,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.83,-2.83,,,0.604,H,A,0.75,-0.33,22.789,22.789,92.05,HAB,-2.633,0.295029,0.0113863,0.996433 kka2_1:2_A79A,kka2_1:2_79,Kka2,kka2_1:2,P00552,0.996437,NO,79,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.368,-2.368,,,0.563,.,B,0.46,-0.43,0.475,,71.59,HHH,-1.752,0.295029,0.00664821,0.996437 beta-lactamase_625_T269A,beta-lactamase_625_269,TEM-1,beta-lactamase_625,P62593,0.996438,NO,269,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.213352,0.00950944,0.996438 beta-lactamase_39_G240S,beta-lactamase_39_240,TEM-1,beta-lactamase_39,P62593,0.996439,NO,240,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.537,-2.475,0.938,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.0495842,0.00591201,0.996439 beta-lactamase_39_S241R,beta-lactamase_39_241,TEM-1,beta-lactamase_39,P62593,0.996442,NO,241,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.433,-3.314,1.881,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.0495842,0.00452736,0.996442 beta-lactamase_625_H156T,beta-lactamase_625_156,TEM-1,beta-lactamase_625,P62593,0.996444,NO,156,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-3.156,-2.632,-0.524,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.213352,0.00468596,0.996444 beta-lactamase_D33L,beta-lactamase_33,TEM-1,beta-lactamase,P62593,0.996444,NO,33,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.321,-2.326,0.005,5.05203,0.366,H,A,0.23,0.33,2.032,,77.62,BAH,-2.12133,0.221079,0.00435556,0.996444 beta-lactamase_P217Q,beta-lactamase_217,TEM-1,beta-lactamase,P62593,0.996444,NO,217,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-2.062,-3.933,1.871,5.19872,0.496,I,A,0.99,-0.33,0.431,,74.48,OOH,-1.64333,0.221079,0.00463211,0.996444 beta-lactamase_P60M,beta-lactamase_60,TEM-1,beta-lactamase,P62593,0.996444,NO,60,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-2.469,-4.701,2.232,5.51353,0.256,T,A,0.73,-0.56,3.653,,77.62,BOA,-1.97633,0.221079,0.00521318,0.996444 beta-lactamase_S221Q,beta-lactamase_221,TEM-1,beta-lactamase,P62593,0.996444,NO,221,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.754,-3.871,2.117,5.77407,0.624,H,A,0.74,-0.2,0.383,,74.48,BPH,-1.59967,0.221079,0.0046094,0.996444 beta-lactamase_39_E210D,beta-lactamase_39_210,TEM-1,beta-lactamase_39,P62593,0.996445,NO,210,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.319,-3.702,1.383,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.0495842,0.00663582,0.996445 beta-lactamase_39_M184Q,beta-lactamase_39_184,TEM-1,beta-lactamase_39,P62593,0.996446,NO,184,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.593,-3.011,1.418,,,H,A,0.55,-0.87,2.893,,62.94,HHH,-1.41,0.0495842,0.00356019,0.996446 beta-lactamase_156_A77I,beta-lactamase_156_77,TEM-1,beta-lactamase_156,P62593,0.996447,NO,77,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.234,-3.583,2.349,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.111618,0.00282362,0.996447 beta-lactamase_156_S96K,beta-lactamase_156_96,TEM-1,beta-lactamase_156,P62593,0.996448,NO,96,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.27,-2.895,0.625,,0.368,,b,0.27,0.39,2.838,,73.78,HPP,-2.019,0.111618,0.00551835,0.996448 kka2_1:8_A65G,kka2_1:8_65,Kka2,kka2_1:8,P00552,0.996449,NO,65,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.744,-2.917,1.173,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.100394,0.00709258,0.996449 kka2_1:8_A65G,kka2_1:8_65,Kka2,kka2_1:8,P00552,0.996449,NO,65,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.744,-2.917,1.173,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.100394,0.00709258,0.996449 beta-lactamase_39_L284G,beta-lactamase_39_284,TEM-1,beta-lactamase_39,P62593,0.996459,NO,284,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.0495842,0.0686156,0.996459 beta-lactamase_156_V82R,beta-lactamase_156_82,TEM-1,beta-lactamase_156,P62593,0.99646,NO,82,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.325,-4.101,2.776,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.111618,0.00397046,0.99646 beta-lactamase_625_H151S,beta-lactamase_625_151,TEM-1,beta-lactamase_625,P62593,0.996461,NO,151,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-2.96,-2.636,-0.324,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.213352,0.00216946,0.996461 kka2_1:1_A248M,kka2_1:1_248,Kka2,kka2_1:1,P00552,0.99647,NO,248,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.124,-4.765,2.641,,0.825,S,b,0.46,0.46,24.72,24.72,92.05,HHO,-2.15,0.520039,0.0125484,0.99647 beta-lactamase_39_S266H,beta-lactamase_39_266,TEM-1,beta-lactamase_39,P62593,0.996471,NO,266,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.0495842,0.0140785,0.996471 beta-lactamase_2500_E166A,beta-lactamase_2500_166,TEM-1,beta-lactamase_2500,P62593,0.996472,NO,166,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.756,-2.056,0.3,,0.508,G,A,1.04,1.05,2.124,,73.08,OAH,-1.42233,0.361275,0.00512989,0.996472 beta-lactamase_156_Q204Y,beta-lactamase_156_204,TEM-1,beta-lactamase_156,P62593,0.99648,NO,204,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-1.382,-4.071,2.689,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.111618,0.00364106,0.99648 kka2_1:8_C192G,kka2_1:8_192,Kka2,kka2_1:8,P00552,0.996482,NO,192,C,G,CG,Special,Special,5.07,3.29388,-1.77612,159,121,75,-46,108.5,60.1,-48.4,-1.067,-3.557,2.49,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.100394,0.00485428,0.996482 kka2_1:8_C192G,kka2_1:8_192,Kka2,kka2_1:8,P00552,0.996482,NO,192,C,G,CG,Special,Special,5.07,3.29388,-1.77612,159,121,75,-46,108.5,60.1,-48.4,-1.067,-3.557,2.49,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.100394,0.00485428,0.996482 beta-lactamase_2500_D113Q,beta-lactamase_2500_113,TEM-1,beta-lactamase_2500,P62593,0.996483,NO,113,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.829,-2.873,1.044,,0.665,T,A,0.75,0.91,21.104,21.104,73.08,PAO,-1.703,0.361275,0.00474112,0.996483 beta-lactamase_625_T139Q,beta-lactamase_625_139,TEM-1,beta-lactamase_625,P62593,0.996485,NO,139,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.901,-2.8,0.899,,0.216,H,A,0.22,0.39,2.256,,77.62,PPH,-2.04667,0.213352,0.00441837,0.996485 beta-lactamase_625_H24I,beta-lactamase_625_24,TEM-1,beta-lactamase_625,P62593,0.996492,NO,24,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-2.481,-3.874,1.393,,,,,,,2.708,,93.01,OBO,-2.0035,0.213352,0.00238894,0.996492 beta-lactamase_625_D113T,beta-lactamase_625_113,TEM-1,beta-lactamase_625,P62593,0.996494,NO,113,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.829,-2.544,0.715,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.213352,0.00474112,0.996494 kka2_1:2_E96E,kka2_1:2_96,Kka2,kka2_1:2,P00552,0.996497,NO,96,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.573,-2.573,,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.295029,0.00369441,0.996497 kka2_1:8_Q27Y,kka2_1:8_27,Kka2,kka2_1:8,P00552,0.996499,NO,27,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-1.659,-4.273,2.614,,0.608,.,A,0.64,0.71,3.919,,65.53,PPP,-1.90733,0.100394,0.00595365,0.996499 kka2_1:8_Q27Y,kka2_1:8_27,Kka2,kka2_1:8,P00552,0.996499,NO,27,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-1.659,-4.273,2.614,,0.608,.,A,0.64,0.71,3.919,,65.53,PPP,-1.90733,0.100394,0.00595365,0.996499 beta-lactamase_625_A268L,beta-lactamase_625_268,TEM-1,beta-lactamase_625,P62593,0.996508,NO,268,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.213352,0.0102525,0.996508 beta-lactamase_39_L146T,beta-lactamase_39_146,TEM-1,beta-lactamase_39,P62593,0.996509,NO,146,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.462,-3.533,2.071,,0.007,H,A,0.55,-0.56,1.953,,64.69,AHP,-1.656,0.0495842,0.00474542,0.996509 beta-lactamase_39_V82G,beta-lactamase_39_82,TEM-1,beta-lactamase_39,P62593,0.996509,NO,82,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.325,-2.644,1.319,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.0495842,0.00397046,0.996509 beta-lactamase_0_L100D,beta-lactamase_0_100,TEM-1,beta-lactamase_0,P62593,0.996513,NO,100,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.218,-4.132,2.914,,0.343,,B,0.55,0.13,1.373,,63.29,AHH,-1.23467,0.0500837,0.00413885,0.996513 beta-lactamase_G194D,beta-lactamase_194,TEM-1,beta-lactamase,P62593,0.996513,NO,194,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.396,-2.314,0.918,5.46622,0.276,S,b,0.77,0.36,3.593,,67.83,POA,-1.832,0.221079,0.00392163,0.996513 beta-lactamase_625_E195N,beta-lactamase_625_195,TEM-1,beta-lactamase_625,P62593,0.996514,NO,195,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.186,-2.977,0.791,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.213352,0.00496565,0.996514 beta-lactamase_2500_I171V,beta-lactamase_2500_171,TEM-1,beta-lactamase_2500,P62593,0.996518,NO,171,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-2.431,-3.274,0.843,,0.361,,B,0.48,0.53,1.66,,77.62,HHO,-1.55533,0.361275,0.00623355,0.996518 PSD95pdz3_D332K,PSD95pdz3_332,PSD95pdz3,PSD95pdz3,P31016,0.99652,NO,332,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.264,-3.139,1.875,6.09878,,,,,48.762,,,,AAO,-1.22533,0.0758425,0.000937818,0.99652 beta-lactamase_156_L100T,beta-lactamase_156_100,TEM-1,beta-lactamase_156,P62593,0.996522,NO,100,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.218,-3.502,2.284,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.111618,0.00413885,0.996522 beta-lactamase_39_K190M,beta-lactamase_39_190,TEM-1,beta-lactamase_39,P62593,0.996523,NO,190,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.994,-4.714,2.72,,0.371,H,A,2.34,0.16,1.513,,77.62,BBH,-1.64167,0.0495842,0.00574527,0.996523 beta-lactamase_625_G142S,beta-lactamase_625_142,TEM-1,beta-lactamase_625,P62593,0.996526,NO,142,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.707,-2.438,1.731,,0.034,,p,0.29,-0.64,1.35,,64.69,OOO,-0.834,0.213352,0.00060149,0.996526 beta-lactamase_0_L205P,beta-lactamase_0_205,TEM-1,beta-lactamase_0,P62593,0.996531,NO,205,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.922,-4.159,3.237,,,H,A,0.55,-0.46,1.065,,42.31,PHH,-1.57767,0.0500837,0.00255802,0.996531 kka2_1:8_N58C,kka2_1:8_58,Kka2,kka2_1:8,P00552,0.996532,NO,58,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-2.641,-2.921,0.28,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.100394,0.00793425,0.996532 kka2_1:8_N58C,kka2_1:8_58,Kka2,kka2_1:8,P00552,0.996532,NO,58,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-2.641,-2.921,0.28,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.100394,0.00793425,0.996532 kka2_1:2_A255E,kka2_1:2_255,Kka2,kka2_1:2,P00552,0.996535,NO,255,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.715,-2.621,0.906,,0.466,H,A,0.46,-0.52,5.144,,65.53,HHH,-1.71267,0.295029,0.0126809,0.996535 beta-lactamase_2500_G90A,beta-lactamase_2500_90,TEM-1,beta-lactamase_2500,P62593,0.996538,NO,90,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-2.091,-2.713,0.622,,0.598,T,A,0.29,0.32,1.2,,77.62,HOB,-1.52633,0.361275,0.00490273,0.996538 beta-lactamase_156_C75S,beta-lactamase_156_75,TEM-1,beta-lactamase_156,P62593,0.996542,NO,75,C,S,CS,Special,Polar,5.07,5.68,0.61,112,121,105,-16,108.5,89,-19.5,-1.245,-2.597,1.352,,,H,A,0.46,-0.87,0.876,,50,HOO,-1.24333,0.111618,0.0034616,0.996542 beta-lactamase_39_R159G,beta-lactamase_39_159,TEM-1,beta-lactamase_39,P62593,0.996547,NO,159,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-0.94,-3.384,2.444,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.0495842,0.00108472,0.996547 beta-lactamase_2500_N152E,beta-lactamase_2500_152,TEM-1,beta-lactamase_2500,P62593,0.996551,NO,152,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-2.757,-2.679,-0.078,,0.863,H,A,0.61,0.92,2.061,,77.62,BPH,-2.97,0.361275,0.00471429,0.996551 beta-lactamase_39_R273S,beta-lactamase_39_273,TEM-1,beta-lactamase_39,P62593,0.996558,NO,273,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.314,-3.326,1.012,,0.564,H,A,1.2,1.57,2.163,,73.78,ABP,-1.841,0.0495842,0.0077952,0.996558 PSD95pdz3_D366K,PSD95pdz3_366,PSD95pdz3,PSD95pdz3,P31016,0.996558,NO,366,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.264,-3.139,1.875,5.55684,,,,,20.2375,,,,HAH,-1.401,0.0758425,0.000481272,0.996558 beta-lactamase_156_E279N,beta-lactamase_156_279,TEM-1,beta-lactamase_156,P62593,0.99656,NO,279,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.111618,0.0192826,0.99656 beta-lactamase_156_E210G,beta-lactamase_156_210,TEM-1,beta-lactamase_156,P62593,0.996563,NO,210,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.319,-3.66,1.341,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.111618,0.00663582,0.996563 beta-lactamase_625_A230M,beta-lactamase_625_230,TEM-1,beta-lactamase_625,P62593,0.996563,NO,230,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.154,-4.69,3.536,,0.01,E,B,0.46,-1.17,0.777,,50,HHA,-1.079,0.213352,0.00516841,0.996563 kka2_1:1_L60D,kka2_1:1_60,Kka2,kka2_1:1,P00552,0.996564,NO,60,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.997,-4.183,3.186,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.520039,0.00262176,0.996564 kka2_1:8_L232M,kka2_1:8_232,Kka2,kka2_1:8,P00552,0.996565,NO,232,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.514,-4.338,2.824,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.100394,0.00800103,0.996565 kka2_1:8_L232M,kka2_1:8_232,Kka2,kka2_1:8,P00552,0.996565,NO,232,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.514,-4.338,2.824,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.100394,0.00800103,0.996565 beta-lactamase_156_A278E,beta-lactamase_156_278,TEM-1,beta-lactamase_156,P62593,0.996568,NO,278,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.111618,0.0310297,0.996568 beta-lactamase_156_F64V,beta-lactamase_156_64,TEM-1,beta-lactamase_156,P62593,0.99657,NO,64,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-0.841,-3.304,2.463,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.111618,0.000947691,0.99657 beta-lactamase_K144L,beta-lactamase_144,TEM-1,beta-lactamase,P62593,0.996571,NO,144,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-2.388,-3.577,1.189,6.02507,0.863,H,A,2.81,1.27,0.515,,77.62,OBA,-1.904,0.221079,0.00481141,0.996571 kka2_1:4_R173R,kka2_1:4_173,Kka2,kka2_1:4,P00552,0.996576,NO,173,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.407,-2.407,,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.168804,0.00784999,0.996576 beta-lactamase_625_V157S,beta-lactamase_625_157,TEM-1,beta-lactamase_625,P62593,0.996581,NO,157,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.751,-2.878,1.127,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.213352,0.00506849,0.996581 beta-lactamase_156_A235I,beta-lactamase_156_235,TEM-1,beta-lactamase_156,P62593,0.996582,NO,235,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.266,-3.683,2.417,,0.32,E,B,0.46,-0.86,1.344,,50,OHO,-0.89,0.111618,0.00493474,0.996582 beta-lactamase_2500_Q267H,beta-lactamase_2500_267,TEM-1,beta-lactamase_2500,P62593,0.996582,NO,267,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.361275,0.0102128,0.996582 beta-lactamase_39_E166F,beta-lactamase_39_166,TEM-1,beta-lactamase_39,P62593,0.996584,NO,166,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.756,-4.345,2.589,,0.508,G,A,1.04,1.05,17.227,17.227,73.08,OAH,-1.42233,0.0495842,0.00512989,0.996584 beta-lactamase_E237K,beta-lactamase_237,TEM-1,beta-lactamase,P62593,0.996585,NO,237,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.058,-2.895,0.837,5.42877,0.583,S,B,1.62,1.2,2.144,,77.62,OAB,-1.61467,0.221079,0.0048626,0.996585 beta-lactamase_39_I280L,beta-lactamase_39_280,TEM-1,beta-lactamase_39,P62593,0.996587,NO,280,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.0495842,0.0530888,0.996587 beta-lactamase_39_G236T,beta-lactamase_39_236,TEM-1,beta-lactamase_39,P62593,0.996594,NO,236,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.784,-3.55,2.766,,0.241,,b,0.29,-0.59,1.883,,64.69,HOO,-1.025,0.0495842,0.00162372,0.996594 beta-lactamase_625_Q204Y,beta-lactamase_625_204,TEM-1,beta-lactamase_625,P62593,0.996594,NO,204,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-1.382,-4.071,2.689,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.213352,0.00364106,0.996594 beta-lactamase_156_F70W,beta-lactamase_156_70,TEM-1,beta-lactamase_156,P62593,0.996595,NO,70,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.169,-4.623,3.454,,,H,A,0.58,-1.34,1.918,,63.99,PHB,-0.980667,0.111618,0.00193499,0.996595 beta-lactamase_625_L49F,beta-lactamase_625_49,TEM-1,beta-lactamase_625,P62593,0.996596,NO,49,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.897,-3.092,1.195,,0.131,T,A,0.55,0.04,3.112,,64.69,AHP,-1.99233,0.213352,0.00401477,0.996596 beta-lactamase_2500_K254L,beta-lactamase_2500_254,TEM-1,beta-lactamase_2500,P62593,0.996598,NO,254,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.361275,0.00369,0.996598 beta-lactamase_156_N152D,beta-lactamase_156_152,TEM-1,beta-lactamase_156,P62593,0.996599,NO,152,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-2.757,-3.573,0.816,,0.863,H,A,0.61,0.92,4.038,,77.62,BPH,-2.97,0.111618,0.00471429,0.996599 beta-lactamase_625_K144A,beta-lactamase_625_144,TEM-1,beta-lactamase_625,P62593,0.9966,NO,144,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-2.388,-2.013,-0.375,,0.863,H,A,2.34,1.27,2.313,,77.62,OBA,-1.904,0.213352,0.00481141,0.9966 beta-lactamase_39_D231Q,beta-lactamase_39_231,TEM-1,beta-lactamase_39,P62593,0.996603,NO,231,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.816,-3.637,2.821,,,E,B,0.75,-1.06,0.462,,65.38,HAB,-0.994,0.0495842,0.00107395,0.996603 beta-lactamase_2500_Q37T,beta-lactamase_2500_37,TEM-1,beta-lactamase_2500,P62593,0.996604,NO,37,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.134,-2.508,0.374,,0.613,H,A,0.64,1.98,1.318,,73.08,APH,-2.06967,0.361275,0.00425833,0.996604 beta-lactamase_K232K,beta-lactamase_232,TEM-1,beta-lactamase,P62593,0.996604,NO,232,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.012,-1.012,,5.18286,,E,B,2.92,-1.1,1.174,,65.03,ABP,-1.238,0.221079,0.00313441,0.996604 beta-lactamase_156_R189M,beta-lactamase_156_189,TEM-1,beta-lactamase_156,P62593,0.996605,NO,189,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.844,-4.718,2.874,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.111618,0.0050699,0.996605 beta-lactamase_39_G253N,beta-lactamase_39_253,TEM-1,beta-lactamase_39,P62593,0.996605,NO,253,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.0495842,0.00786358,0.996605 beta-lactamase_A246A,beta-lactamase_246,TEM-1,beta-lactamase,P62593,0.996607,NO,246,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.121,-2.121,,4.78979,0.01,E,B,0.52,-1.01,1.26,,73.78,HHH,-1.55633,0.221079,0.00569458,0.996607 beta-lactamase_625_K32I,beta-lactamase_625_32,TEM-1,beta-lactamase_625,P62593,0.996612,NO,32,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.984,-2.835,0.851,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.213352,0.00401283,0.996612 beta-lactamase_2500_S256Q,beta-lactamase_2500_256,TEM-1,beta-lactamase_2500,P62593,0.996613,NO,256,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.361275,0.00710634,0.996613 beta-lactamase_156_A222T,beta-lactamase_156_222,TEM-1,beta-lactamase_156,P62593,0.996619,NO,222,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.103,-2.805,0.702,,0.233,H,A,0.46,-0.25,2.461,,77.62,PHH,-1.63733,0.111618,0.00466094,0.996619 beta-lactamase_2500_T138N,beta-lactamase_2500_138,TEM-1,beta-lactamase_2500,P62593,0.99662,NO,138,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.506,-2.961,0.455,,0.662,H,A,0.22,-0.03,30.445,30.445,73.78,HPP,-1.81233,0.361275,0.00487868,0.99662 beta-lactamase_625_M67I,beta-lactamase_625_67,TEM-1,beta-lactamase_625,P62593,0.99662,NO,67,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-2.231,-2.93,0.699,,0.006,G,P,0.55,-0.81,2.653,,65.03,HHP,-1.502,0.213352,0.00409753,0.99662 beta-lactamase_H156H,beta-lactamase_156,TEM-1,beta-lactamase,P62593,0.99662,NO,156,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-3.156,-3.156,,6.00284,0.753,S,A,0.72,-0.6,6.456,6.456,77.62,ABH,-1.932,0.221079,0.00468596,0.99662 beta-lactamase_156_P172L,beta-lactamase_156_172,TEM-1,beta-lactamase_156,P62593,0.996626,NO,172,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.998,-2.658,1.66,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.111618,0.00312594,0.996626 beta-lactamase_156_M127W,beta-lactamase_156_127,TEM-1,beta-lactamase_156,P62593,0.996627,NO,127,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-2.251,-3.502,1.251,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.111618,0.00437927,0.996627 beta-lactamase_39_T269A,beta-lactamase_39_269,TEM-1,beta-lactamase_39,P62593,0.996635,NO,269,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.156,,,,0.646,H,A,0.53,0.4,3.889,,77.62,HPH,-1.96733,0.0495842,0.00950944,0.996635 beta-lactamase_156_D207N,beta-lactamase_156_207,TEM-1,beta-lactamase_156,P62593,0.996642,NO,207,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.064,-2.966,0.902,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.111618,0.00592942,0.996642 beta-lactamase_39_G90Y,beta-lactamase_39_90,TEM-1,beta-lactamase_39,P62593,0.996649,NO,90,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-2.091,-4.355,2.264,,0.598,T,A,0.29,0.32,30.794,30.794,77.62,HOB,-1.52633,0.0495842,0.00490273,0.996649 kka2_1:2_I2I,kka2_1:2_2,Kka2,kka2_1:2,P00552,0.996649,NO,2,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.787,-1.787,,,,,,,,5.773,,71.59,HHA,-1.92433,0.295029,0.00246644,0.996649 beta-lactamase_156_K213Q,beta-lactamase_156_213,TEM-1,beta-lactamase_156,P62593,0.996651,NO,213,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.81,-2.028,0.218,,0.67,,A,2.34,0.29,3.924,,67.83,ABH,-1.57767,0.111618,0.00610411,0.996651 beta-lactamase_156_V157K,beta-lactamase_156_157,TEM-1,beta-lactamase_156,P62593,0.996653,NO,157,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.751,-2.698,0.947,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.111618,0.00506849,0.996653 beta-lactamase_156_R176P,beta-lactamase_156_176,TEM-1,beta-lactamase_156,P62593,0.996656,NO,176,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-0.863,-3.88,3.017,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.111618,0.00105554,0.996656 Pab1_E161E,Pab1_161,Pab1,Pab1,P04147,0.996656,NO,161,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.474,-1.474,,,0.663,T,a,,1.34,,,,AAP,-1.59067,0.175299,0.00276141,0.996656 beta-lactamase_S122F,beta-lactamase_122,TEM-1,beta-lactamase,P62593,0.996662,NO,122,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.406,-3.279,0.873,4.87767,0.352,H,A,0.73,-0.54,1.581,,77.62,OPH,-1.39767,0.221079,0.00497825,0.996662 kka2_1:2_E3E,kka2_1:2_3,Kka2,kka2_1:2,P00552,0.996662,NO,3,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.199,-2.199,,,,,,,,7.22,,92.05,HAP,-2.11567,0.295029,0.00267607,0.996662 kka2_1:1_V83V,kka2_1:1_83,Kka2,kka2_1:1,P00552,0.996663,NO,83,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-2.567,-2.567,,,0.358,E,B,0.44,0.53,5.931,,71.59,AHH,-2.264,0.520039,0.00650486,0.996663 beta-lactamase_156_L89V,beta-lactamase_156_89,TEM-1,beta-lactamase_156,P62593,0.996665,NO,89,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.096,-3.043,1.947,,0.168,T,A,0.55,0.63,2.633,,64.34,PHO,-1.75767,0.111618,0.00207068,0.996665 beta-lactamase_156_T139Y,beta-lactamase_156_139,TEM-1,beta-lactamase_156,P62593,0.996669,NO,139,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.901,-4.252,2.351,,0.216,H,A,0.22,0.39,16.34,16.34,77.62,PPH,-2.04667,0.111618,0.00441837,0.996669 Pab1_I157M,Pab1_157,Pab1,Pab1,P04147,0.996671,NO,157,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.623,-3.918,2.295,,,,,,,1.439,,79.72,BHH,-1.28667,0.175299,0.0018103,0.996671 beta-lactamase_156_M115Q,beta-lactamase_156_115,TEM-1,beta-lactamase_156,P62593,0.996678,NO,115,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.389,-3.893,2.504,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.111618,0.0034337,0.996678 beta-lactamase_156_T126G,beta-lactamase_156_126,TEM-1,beta-lactamase_156,P62593,0.996678,NO,126,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.122,-2.22,1.098,,0.05,H,A,0.22,-0.05,1.14,,44.41,HPH,-1.60467,0.111618,0.00244552,0.996678 beta-lactamase_625_R159A,beta-lactamase_625_159,TEM-1,beta-lactamase_625,P62593,0.996678,NO,159,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-0.94,-3.127,2.187,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.213352,0.00108472,0.996678 beta-lactamase_156_L192Q,beta-lactamase_156_192,TEM-1,beta-lactamase_156,P62593,0.996679,NO,192,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.254,-4.246,2.992,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.111618,0.00558728,0.996679 beta-lactamase_39_Q276K,beta-lactamase_39_276,TEM-1,beta-lactamase_39,P62593,0.996683,NO,276,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.0495842,0.0191712,0.996683 beta-lactamase_0_A182L,beta-lactamase_0_182,TEM-1,beta-lactamase_0,P62593,0.996691,NO,182,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.777,-3.486,1.709,,0.136,H,A,0.46,-0.66,10.765,10.765,93.01,OHH,-1.27367,0.0500837,0.00559099,0.996691 beta-lactamase_625_D207S,beta-lactamase_625_207,TEM-1,beta-lactamase_625,P62593,0.996698,NO,207,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.064,-2.656,0.592,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.213352,0.00592942,0.996698 kka2_1:4_G234G,kka2_1:4_234,Kka2,kka2_1:4,P00552,0.996701,NO,234,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-2.9,-2.9,,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.168804,0.00984449,0.996701 kka2_1:2_Q4Q,kka2_1:2_4,Kka2,kka2_1:2,P00552,0.996703,NO,4,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.361,-2.361,,,,,,,,2.026,,71.59,APA,-1.95533,0.295029,0.00239179,0.996703 beta-lactamase_39_L135V,beta-lactamase_39_135,TEM-1,beta-lactamase_39,P62593,0.996704,NO,135,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.002,-2.8,1.798,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.0495842,0.00244423,0.996704 Pab1_N162G,Pab1_162,Pab1,Pab1,P04147,0.996707,NO,162,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-2.313,-3.381,1.068,,0.681,T,A,,1.12,,,,APO,-1.532,0.175299,0.0030719,0.996707 beta-lactamase_156_H156P,beta-lactamase_156_156,TEM-1,beta-lactamase_156,P62593,0.996709,NO,156,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-3.156,-2.552,-0.604,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.111618,0.00468596,0.996709 beta-lactamase_156_W163E,beta-lactamase_156_163,TEM-1,beta-lactamase_156,P62593,0.996709,NO,163,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-1.843,-3.693,1.85,,0.467,,B,0.47,-0.5,15.095,15.095,63.99,BHA,-1.269,0.111618,0.00418955,0.996709 beta-lactamase_2500_L192M,beta-lactamase_2500_192,TEM-1,beta-lactamase_2500,P62593,0.99671,NO,192,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.254,-4.084,2.83,,0.095,H,A,0.55,0.35,1.902,,60.14,HHP,-1.41833,0.361275,0.00558728,0.99671 beta-lactamase_625_D36A,beta-lactamase_625_36,TEM-1,beta-lactamase_625,P62593,0.996715,NO,36,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.732,-2.434,-0.298,,0.555,H,A,0.75,1.17,2.26,,77.62,AAP,-1.91167,0.213352,0.00476483,0.996715 beta-lactamase_156_Q37V,beta-lactamase_156_37,TEM-1,beta-lactamase_156,P62593,0.996725,NO,37,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.134,-3.664,1.53,,0.613,H,A,0.64,1.98,12.052,12.052,73.08,APH,-2.06967,0.111618,0.00425833,0.996725 beta-lactamase_156_R202L,beta-lactamase_156_202,TEM-1,beta-lactamase_156,P62593,0.99673,NO,202,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.292,-3.422,2.13,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.111618,0.00321899,0.99673 beta-lactamase_2500_A200E,beta-lactamase_2500_200,TEM-1,beta-lactamase_2500,P62593,0.996731,NO,200,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.878,-2.662,0.784,,0.757,H,A,0.46,-0.19,0.436,,77.62,HHP,-2.001,0.361275,0.0060056,0.996731 beta-lactamase_156_S57K,beta-lactamase_156_57,TEM-1,beta-lactamase_156,P62593,0.996732,NO,57,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.918,-3.565,1.647,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.111618,0.00492804,0.996732 beta-lactamase_156_G226W,beta-lactamase_156_226,TEM-1,beta-lactamase_156,P62593,0.996737,NO,226,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.461,-5.464,4.003,,0.701,T,l,0.29,-0.25,3.199,,74.48,HOH,-1.42933,0.111618,0.00665294,0.996737 beta-lactamase_156_S57L,beta-lactamase_156_57,TEM-1,beta-lactamase_156,P62593,0.996742,NO,57,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.918,-2.848,0.93,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.111618,0.00492804,0.996742 beta-lactamase_39_K53R,beta-lactamase_39_53,TEM-1,beta-lactamase_39,P62593,0.996751,NO,53,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-2.313,-2.027,-0.286,,0.589,,B,2.34,1.15,15.633,15.633,77.62,OBH,-2.1,0.0495842,0.00383383,0.996751 beta-lactamase_39_Q204E,beta-lactamase_39_204,TEM-1,beta-lactamase_39,P62593,0.996752,NO,204,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-1.382,-3.106,1.724,,0.204,H,A,0.64,0.09,0.489,,66.08,PPH,-1.49067,0.0495842,0.00364106,0.996752 beta-lactamase_156_R92E,beta-lactamase_156_92,TEM-1,beta-lactamase_156,P62593,0.996753,NO,92,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.718,-2.624,0.906,,0.479,E,B,1.2,1.36,19.112,19.112,65.38,BBH,-1.50367,0.111618,0.00429626,0.996753 beta-lactamase_156_T147W,beta-lactamase_156_147,TEM-1,beta-lactamase_156,P62593,0.996757,NO,147,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.149,-5.268,4.119,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.111618,0.00226017,0.996757 beta-lactamase_625_Q86A,beta-lactamase_625_86,TEM-1,beta-lactamase_625,P62593,0.996771,NO,86,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.4,-2.601,0.201,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.213352,0.00450027,0.996771 beta-lactamase_625_T198C,beta-lactamase_625_198,TEM-1,beta-lactamase_625,P62593,0.996771,NO,198,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.168,-4.902,2.734,,0.489,,B,0.22,-0.13,0.37,,73.78,HPH,-1.98767,0.213352,0.004311,0.996771 beta-lactamase_39_A84H,beta-lactamase_39_84,TEM-1,beta-lactamase_39,P62593,0.996776,NO,84,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.651,-3.344,1.693,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.0495842,0.00503822,0.996776 beta-lactamase_625_E119N,beta-lactamase_625_119,TEM-1,beta-lactamase_625,P62593,0.996776,NO,119,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.412,-3.591,2.179,,0.358,H,A,1.04,0.51,1.034,,63.99,BAH,-1.623,0.213352,0.00386966,0.996776 kka2_1:2_E161Q,kka2_1:2_161,Kka2,kka2_1:2,P00552,0.996776,NO,161,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.581,-3.792,2.211,,0.829,G,A,1.52,2.24,1.612,,92.05,AAB,-1.861,0.295029,0.00760103,0.996776 kka2_1:2_Q155Q,kka2_1:2_155,Kka2,kka2_1:2,P00552,0.99678,NO,155,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.606,-2.606,,,0.525,T,A,0.64,1.49,1.592,,63.64,APA,-1.726,0.295029,0.00641853,0.99678 beta-lactamase_625_A148D,beta-lactamase_625_148,TEM-1,beta-lactamase_625,P62593,0.996783,NO,148,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.757,-2.341,0.584,,0.379,H,A,0.46,-0.55,1.359,,72.73,PHH,-1.40167,0.213352,0.00547053,0.996783 beta-lactamase_156_A222S,beta-lactamase_156_222,TEM-1,beta-lactamase_156,P62593,0.996785,NO,222,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.103,-2.253,0.15,,0.233,H,A,0.46,-0.25,2.461,,77.62,PHH,-1.63733,0.111618,0.00466094,0.996785 beta-lactamase_2500_D207N,beta-lactamase_2500_207,TEM-1,beta-lactamase_2500,P62593,0.996787,NO,207,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.064,-2.966,0.902,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.361275,0.00592942,0.996787 beta-lactamase_2500_A170S,beta-lactamase_2500_170,TEM-1,beta-lactamase_2500,P62593,0.996789,NO,170,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.237,-3.188,1.951,,0.126,,L,0.46,-0.35,2.427,,64.69,AHH,-1.63267,0.361275,0.00431903,0.996789 beta-lactamase_156_E169W,beta-lactamase_156_169,TEM-1,beta-lactamase_156,P62593,0.99679,NO,169,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.23,-5.379,4.149,,0.337,,A,1.04,1,3.516,,73.08,PAH,-1.16533,0.111618,0.00400994,0.99679 beta-lactamase_39_T147S,beta-lactamase_39_147,TEM-1,beta-lactamase_39,P62593,0.99679,NO,147,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.149,-2.487,1.338,,0.281,H,A,0.22,-0.68,13.843,13.843,64.34,HPH,-1.456,0.0495842,0.00226017,0.99679 beta-lactamase_156_V260C,beta-lactamase_156_260,TEM-1,beta-lactamase_156,P62593,0.996798,NO,260,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.111618,0.00471757,0.996798 beta-lactamase_625_G253V,beta-lactamase_625_253,TEM-1,beta-lactamase_625,P62593,0.996799,NO,253,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.213352,0.00786358,0.996799 beta-lactamase_625_E102F,beta-lactamase_625_102,TEM-1,beta-lactamase_625,P62593,0.996805,NO,102,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.118,-4.365,2.247,,0.722,S,B,1.04,1.82,1.336,,73.08,HAH,-1.581,0.213352,0.00486633,0.996805 kka2_1:1_D5G,kka2_1:1_5,Kka2,kka2_1:1,P00552,0.996811,NO,5,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.306,-3.014,1.708,,,,,,,0.895,,71.59,PAO,-1.784,0.520039,0.00222864,0.996811 beta-lactamase_39_D271N,beta-lactamase_39_271,TEM-1,beta-lactamase_39,P62593,0.996815,NO,271,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.0495842,0.00752082,0.996815 beta-lactamase_625_K32S,beta-lactamase_625_32,TEM-1,beta-lactamase_625,P62593,0.996818,NO,32,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.984,-3.371,1.387,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.213352,0.00401283,0.996818 beta-lactamase_625_R162C,beta-lactamase_625_162,TEM-1,beta-lactamase_625,P62593,0.996823,NO,162,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.016,-5.08,4.064,,0.124,S,B,1.2,-0.37,1.445,,64.69,ABH,-1.25,0.213352,0.000561334,0.996823 beta-lactamase_156_G85W,beta-lactamase_156_85,TEM-1,beta-lactamase_156,P62593,0.996837,NO,85,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.011,-5.288,4.277,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.111618,0.00252173,0.996837 beta-lactamase_156_E195P,beta-lactamase_156_195,TEM-1,beta-lactamase_156,P62593,0.996841,NO,195,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.186,-2.83,0.644,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.111618,0.00496565,0.996841 beta-lactamase_625_P250I,beta-lactamase_625_250,TEM-1,beta-lactamase_625,P62593,0.996844,NO,250,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.213352,0.00550899,0.996844 beta-lactamase_156_G240A,beta-lactamase_156_240,TEM-1,beta-lactamase_156,P62593,0.996845,NO,240,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.111618,0.00591201,0.996845 beta-lactamase_156_S96P,beta-lactamase_156_96,TEM-1,beta-lactamase_156,P62593,0.996852,NO,96,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.27,-2.878,0.608,,0.368,,b,0.27,0.39,2.838,,73.78,HPP,-2.019,0.111618,0.00551835,0.996852 beta-lactamase_39_S80C,beta-lactamase_39_80,TEM-1,beta-lactamase_39,P62593,0.996855,NO,80,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.029,-4.922,2.893,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.0495842,0.00565569,0.996855 beta-lactamase_625_Q204D,beta-lactamase_625_204,TEM-1,beta-lactamase_625,P62593,0.996856,NO,204,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-1.382,-3.553,2.171,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.213352,0.00364106,0.996856 beta-lactamase_39_L219R,beta-lactamase_39_219,TEM-1,beta-lactamase_39,P62593,0.996857,NO,219,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.313,-4.126,2.813,,,I,A,0.55,-0.51,19.842,19.842,74.48,HHB,-1.21533,0.0495842,0.00664345,0.996857 beta-lactamase_0_M153A,beta-lactamase_0_153,TEM-1,beta-lactamase_0,P62593,0.996859,NO,153,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-3.193,-2.415,-0.778,,0.14,T,A,0.55,-0.11,3.826,,77.62,PHO,-2.25767,0.0500837,0.00509109,0.996859 beta-lactamase_P12Y,beta-lactamase_12,TEM-1,beta-lactamase,P62593,0.996862,NO,12,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-2.016,-2.811,0.795,,,,,,,2.88,,72.73,HOH,-2.05167,0.221079,0.00241653,0.996862 beta-lactamase_625_R239P,beta-lactamase_625_239,TEM-1,beta-lactamase_625,P62593,0.996865,NO,239,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.213352,0.00213852,0.996865 beta-lactamase_39_D174Y,beta-lactamase_39_174,TEM-1,beta-lactamase_39,P62593,0.996867,NO,174,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.738,-4.387,3.649,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.0495842,0.00125633,0.996867 beta-lactamase_156_R91Y,beta-lactamase_156_91,TEM-1,beta-lactamase_156,P62593,0.996872,NO,91,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.392,-4.246,2.854,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.111618,0.00380226,0.996872 beta-lactamase_2500_Q97L,beta-lactamase_2500_97,TEM-1,beta-lactamase_2500,P62593,0.996872,NO,97,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.072,-3.528,1.456,,0.823,G,A,0.64,2.42,1.157,,77.62,PPP,-2.43833,0.361275,0.0045116,0.996872 beta-lactamase_39_L192Y,beta-lactamase_39_192,TEM-1,beta-lactamase_39,P62593,0.996874,NO,192,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.254,-3.913,2.659,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.0495842,0.00558728,0.996874 beta-lactamase_39_V72G,beta-lactamase_39_72,TEM-1,beta-lactamase_39,P62593,0.996876,NO,72,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.658,-3.477,1.819,,,H,A,0.44,-1.03,1.92,,65.73,BHH,-1.32167,0.0495842,0.00501194,0.996876 PSD95pdz3_N369V,PSD95pdz3_369,PSD95pdz3,PSD95pdz3,P31016,0.996877,NO,369,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-1.572,-3.434,1.862,5.91569,,,,,24.1262,0.44,,87.71,BPH,-1.487,0.0758425,0.000608412,0.996877 PSD95pdz3_G351H,PSD95pdz3_351,PSD95pdz3,PSD95pdz3,P31016,0.996882,NO,351,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.008,-4.362,3.354,5.44798,,,,,20.7625,,,,POA,-1.37133,0.0758425,0.000691282,0.996882 beta-lactamase_625_E56N,beta-lactamase_625_56,TEM-1,beta-lactamase_625,P62593,0.996883,NO,56,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.043,-2.542,0.499,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.213352,0.00238534,0.996883 beta-lactamase_625_C75G,beta-lactamase_625_75,TEM-1,beta-lactamase_625,P62593,0.996891,NO,75,C,G,CG,Special,Special,5.07,3.29388,-1.77612,159,121,75,-46,108.5,60.1,-48.4,-1.245,-2.515,1.27,,,H,A,0.46,-0.87,2.141,,50,HOO,-1.24333,0.213352,0.0034616,0.996891 beta-lactamase_625_E279M,beta-lactamase_625_279,TEM-1,beta-lactamase_625,P62593,0.9969,NO,279,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.213352,0.0192826,0.9969 beta-lactamase_S254D,beta-lactamase_254,TEM-1,beta-lactamase,P62593,0.9969,NO,254,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.126,-2.656,0.53,5.49575,0.312,,a,0.25,-0.48,24.91,24.91,69.58,OPB,-2.215,0.221079,0.00369,0.9969 beta-lactamase_625_G216V,beta-lactamase_625_216,TEM-1,beta-lactamase_625,P62593,0.996902,NO,216,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.477,-3.793,2.316,,0.437,I,A,0.29,-0.58,1.718,,74.48,HOO,-1.68067,0.213352,0.00639568,0.996902 PSD95pdz3_F340L,PSD95pdz3_340,PSD95pdz3,PSD95pdz3,P31016,0.996903,NO,340,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.524,-2.59,1.066,5.79283,,,,,11.8045,,,,PHH,-1.55767,0.0758425,0.000836987,0.996903 beta-lactamase_625_I206Y,beta-lactamase_625_206,TEM-1,beta-lactamase_625,P62593,0.996908,NO,206,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-2.429,-4.278,1.849,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.213352,0.00528934,0.996908 beta-lactamase_156_A124T,beta-lactamase_156_124,TEM-1,beta-lactamase_156,P62593,0.996909,NO,124,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.181,-1.586,0.405,,,H,A,0.46,-0.9,2.027,,64.34,HHH,-1.152,0.111618,0.00481399,0.996909 beta-lactamase_625_K286G,beta-lactamase_625_286,TEM-1,beta-lactamase_625,P62593,0.996914,NO,286,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.213352,,0.996914 beta-lactamase_D48D,beta-lactamase_48,TEM-1,beta-lactamase,P62593,0.996917,NO,48,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.101,-1.101,,4.89966,0.189,E,B,0.23,0.21,1.281,,50.35,HAH,-1.62467,0.221079,0.0027273,0.996917 beta-lactamase_F6K,beta-lactamase_6,TEM-1,beta-lactamase,P62593,0.996917,NO,6,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.847,-3.78,1.933,,,,,,,1.276,,67.83,BHB,-2.076,0.221079,0.00261627,0.996917 beta-lactamase_156_E238T,beta-lactamase_156_238,TEM-1,beta-lactamase_156,P62593,0.996918,NO,238,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.111618,0.00743256,0.996918 beta-lactamase_39_Q97H,beta-lactamase_39_97,TEM-1,beta-lactamase_39,P62593,0.996919,NO,97,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.072,-4.636,2.564,,0.823,G,A,0.64,2.42,4.457,,77.62,PPP,-2.43833,0.0495842,0.0045116,0.996919 beta-lactamase_156_E62Q,beta-lactamase_156_62,TEM-1,beta-lactamase_156,P62593,0.99692,NO,62,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.193,-2.5,1.307,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.111618,0.00264802,0.99692 beta-lactamase_156_H24T,beta-lactamase_156_24,TEM-1,beta-lactamase_156,P62593,0.996927,NO,24,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-2.481,-2.645,0.164,,,,,,,2.708,,93.01,OBO,-2.0035,0.111618,0.00238894,0.996927 beta-lactamase_156_A247S,beta-lactamase_156_247,TEM-1,beta-lactamase_156,P62593,0.99693,NO,247,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.111618,0.00611275,0.99693 beta-lactamase_S254G,beta-lactamase_254,TEM-1,beta-lactamase,P62593,0.996931,NO,254,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.126,-3.335,1.209,5.49575,0.312,,a,0.25,-0.48,24.91,24.91,69.58,OPB,-2.215,0.221079,0.00369,0.996931 beta-lactamase_39_I261V,beta-lactamase_39_261,TEM-1,beta-lactamase_39,P62593,0.996934,NO,261,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.0495842,0.0123091,0.996934 beta-lactamase_625_S256A,beta-lactamase_625_256,TEM-1,beta-lactamase_625,P62593,0.996934,NO,256,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.213352,0.00710634,0.996934 beta-lactamase_39_E35I,beta-lactamase_39_35,TEM-1,beta-lactamase_39,P62593,0.996941,NO,35,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-0.869,-4.036,3.167,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.0495842,0.00174441,0.996941 beta-lactamase_39_L192E,beta-lactamase_39_192,TEM-1,beta-lactamase_39,P62593,0.996942,NO,192,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.254,-3.893,2.639,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.0495842,0.00558728,0.996942 beta-lactamase_625_M180W,beta-lactamase_625_180,TEM-1,beta-lactamase_625,P62593,0.996944,NO,180,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-2.795,-5.124,2.329,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.213352,0.00552048,0.996944 beta-lactamase_39_A278R,beta-lactamase_39_278,TEM-1,beta-lactamase_39,P62593,0.996949,NO,278,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.0495842,0.0310297,0.996949 beta-lactamase_625_A225F,beta-lactamase_625_225,TEM-1,beta-lactamase_625,P62593,0.996951,NO,225,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.845,-4.402,2.557,,1,T,B,0.46,-0.38,9.874,9.874,74.48,OHO,-1.39967,0.213352,0.00465057,0.996951 beta-lactamase_2500_Q97K,beta-lactamase_2500_97,TEM-1,beta-lactamase_2500,P62593,0.996955,NO,97,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.072,-2.314,0.242,,0.823,G,A,0.64,2.42,1.157,,77.62,PPP,-2.43833,0.361275,0.0045116,0.996955 beta-lactamase_625_T269P,beta-lactamase_625_269,TEM-1,beta-lactamase_625,P62593,0.996959,NO,269,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.213352,0.00950944,0.996959 beta-lactamase_2500_I171G,beta-lactamase_2500_171,TEM-1,beta-lactamase_2500,P62593,0.99696,NO,171,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-2.431,-3.603,1.172,,0.361,,B,0.48,0.53,1.66,,77.62,HHO,-1.55533,0.361275,0.00623355,0.99696 beta-lactamase_39_T198F,beta-lactamase_39_198,TEM-1,beta-lactamase_39,P62593,0.996965,NO,198,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.168,-4.258,2.09,,0.489,,B,0.22,-0.13,3.614,,73.78,HPH,-1.98767,0.0495842,0.004311,0.996965 beta-lactamase_156_A247W,beta-lactamase_156_247,TEM-1,beta-lactamase_156,P62593,0.996967,NO,247,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.111618,0.00611275,0.996967 beta-lactamase_625_A268T,beta-lactamase_625_268,TEM-1,beta-lactamase_625,P62593,0.996967,NO,268,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.213352,0.0102525,0.996967 beta-lactamase_625_T269N,beta-lactamase_625_269,TEM-1,beta-lactamase_625,P62593,0.996969,NO,269,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.213352,0.00950944,0.996969 beta-lactamase_156_R92F,beta-lactamase_156_92,TEM-1,beta-lactamase_156,P62593,0.996971,NO,92,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.718,-4.33,2.612,,0.479,E,B,1.2,1.36,19.112,19.112,65.38,BBH,-1.50367,0.111618,0.00429626,0.996971 Pab1_N187Q,Pab1_187,Pab1,Pab1,P04147,0.996976,NO,187,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-1.224,-3.545,2.321,,0.456,S,b,,1.87,,,,HPO,-1.272,0.175299,0.00083165,0.996976 beta-lactamase_625_R239S,beta-lactamase_625_239,TEM-1,beta-lactamase_625,P62593,0.996979,NO,239,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.213352,0.00213852,0.996979 beta-lactamase_625_S51L,beta-lactamase_625_51,TEM-1,beta-lactamase_625,P62593,0.996983,NO,51,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.526,-3.495,1.969,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.213352,0.00504821,0.996983 beta-lactamase_39_L160Q,beta-lactamase_39_160,TEM-1,beta-lactamase_39,P62593,0.996987,NO,160,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.977,-4.199,3.222,,0.022,,B,0.55,-0.6,0.895,,44.41,BHA,-0.936,0.0495842,0.00193775,0.996987 beta-lactamase_V117I,beta-lactamase_117,TEM-1,beta-lactamase,P62593,0.996987,NO,117,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.53,-1.923,0.393,5.33594,,H,A,1.19,-0.34,1.182,,65.03,PHB,-1.741,0.221079,0.00467906,0.996987 beta-lactamase_39_S201N,beta-lactamase_39_201,TEM-1,beta-lactamase_39,P62593,0.99699,NO,201,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.183,-3.471,2.288,,0.064,H,A,0.27,-0.07,3.54,,64.69,HPB,-1.451,0.0495842,0.00198815,0.99699 beta-lactamase_625_A170R,beta-lactamase_625_170,TEM-1,beta-lactamase_625,P62593,0.996997,NO,170,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.237,-3.908,2.671,,0.126,,L,0.46,-0.35,3.626,,64.69,AHH,-1.63267,0.213352,0.00431903,0.996997 Pab1_F170F,Pab1_170,Pab1,Pab1,P04147,0.996999,NO,170,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.269,-1.269,,,0.331,E,B,0.87,-1.31,2.061,,79.72,OHH,-1.06367,0.175299,0.000540225,0.996999 beta-lactamase_156_L38H,beta-lactamase_156_38,TEM-1,beta-lactamase_156,P62593,0.997003,NO,38,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.343,-3.182,1.839,,0.088,H,A,0.55,0.2,13.556,13.556,64.34,PHO,-1.78033,0.111618,0.00373244,0.997003 beta-lactamase_39_T116Q,beta-lactamase_39_116,TEM-1,beta-lactamase_39,P62593,0.997004,NO,116,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.28,-3.898,2.618,,0.115,E,B,0.22,-0.12,1.133,,67.48,HPH,-1.39967,0.0495842,0.00336175,0.997004 beta-lactamase_39_L196V,beta-lactamase_39_196,TEM-1,beta-lactamase_39,P62593,0.997009,NO,196,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-2.478,-2.258,-0.22,,0.518,S,A,0.55,1.35,12.152,12.152,77.62,AHH,-1.839,0.0495842,0.00512144,0.997009 beta-lactamase_2500_E145F,beta-lactamase_2500_145,TEM-1,beta-lactamase_2500,P62593,0.99701,NO,145,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.357,-4.373,2.016,,0.545,H,A,1.04,0.79,2.124,,77.62,BAH,-2.069,0.361275,0.00553285,0.99701 beta-lactamase_2500_F149M,beta-lactamase_2500_149,TEM-1,beta-lactamase_2500,P62593,0.997012,NO,149,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.299,-4.454,3.155,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.361275,0.00418462,0.997012 beta-lactamase_2500_S122V,beta-lactamase_2500_122,TEM-1,beta-lactamase_2500,P62593,0.997012,NO,122,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.406,-2.967,0.561,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.361275,0.00497825,0.997012 beta-lactamase_156_L111R,beta-lactamase_156_111,TEM-1,beta-lactamase_156,P62593,0.997021,NO,111,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.76,-4.077,2.317,,0.328,T,A,0.55,0.93,2.26,,64.34,BHP,-1.884,0.111618,0.00480671,0.997021 beta-lactamase_156_T193L,beta-lactamase_156_193,TEM-1,beta-lactamase_156,P62593,0.997028,NO,193,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.914,-1.776,-0.138,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.111618,0.00482669,0.997028 beta-lactamase_39_I45L,beta-lactamase_39_45,TEM-1,beta-lactamase_39,P62593,0.997029,NO,45,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-2.421,-2.39,-0.031,,,E,B,0.48,-0.3,2.256,,77.62,HHA,-2.30267,0.0495842,0.00452842,0.997029 beta-lactamase_39_S283Y,beta-lactamase_39_283,TEM-1,beta-lactamase_39,P62593,0.997029,NO,283,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.0495842,0.0429138,0.997029 beta-lactamase_P25Q,beta-lactamase_25,TEM-1,beta-lactamase,P62593,0.997031,NO,25,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.526,-2.522,0.996,5.6134,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.221079,0.00347571,0.997031 beta-lactamase_39_P165C,beta-lactamase_39_165,TEM-1,beta-lactamase_39,P62593,0.997032,NO,165,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.373,-4.892,3.519,,0.203,T,A,0.52,-0.31,3.907,,73.78,AOA,-1.359,0.0495842,0.00549538,0.997032 beta-lactamase_39_T263R,beta-lactamase_39_263,TEM-1,beta-lactamase_39,P62593,0.997032,NO,263,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.0495842,0.0110582,0.997032 beta-lactamase_39_Q86V,beta-lactamase_39_86,TEM-1,beta-lactamase_39,P62593,0.997034,NO,86,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.4,-2.988,0.588,,0.696,S,A,0.64,2.38,27.704,27.704,77.62,OPA,-1.61067,0.0495842,0.00450027,0.997034 beta-lactamase_625_L135F,beta-lactamase_625_135,TEM-1,beta-lactamase_625,P62593,0.997048,NO,135,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.002,-3.671,2.669,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.213352,0.00244423,0.997048 PSD95pdz3_N381T,PSD95pdz3_381,PSD95pdz3,PSD95pdz3,P31016,0.99705,NO,381,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-1.41,-2.878,1.468,5.66057,,,,,28.2162,,,,BPH,-1.37767,0.0758425,0.000265374,0.99705 beta-lactamase_39_E35C,beta-lactamase_39_35,TEM-1,beta-lactamase_39,P62593,0.997068,NO,35,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-0.869,-5.31,4.441,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.0495842,0.00174441,0.997068 beta-lactamase_625_W163T,beta-lactamase_625_163,TEM-1,beta-lactamase_625,P62593,0.99707,NO,163,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-1.843,-2.765,0.922,,0.467,,B,0.47,-0.5,5.019,,63.99,BHA,-1.269,0.213352,0.00418955,0.99707 beta-lactamase_156_L197P,beta-lactamase_156_197,TEM-1,beta-lactamase_156,P62593,0.997074,NO,197,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.853,-4.068,3.215,,0.007,S,B,0.55,0.33,1.58,,60.14,HHP,-1.833,0.111618,0.00144602,0.997074 kka2_1:2_V83V,kka2_1:2_83,Kka2,kka2_1:2,P00552,0.997074,NO,83,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-2.567,-2.567,,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.295029,0.00650486,0.997074 gb1_D266K,gb1_266,gb1,gb1,P06654,0.997077,NO,266,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.261,-3.356,2.095,,,,,,,0.638,,45.54,HAO,-1.59333,0.177985,0.00394694,0.997077 kka2_1:1_D52D,kka2_1:1_52,Kka2,kka2_1:1,P00552,0.997078,NO,52,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.271,-2.271,,,0.22,E,B,0.75,0.8,2.64,,71.59,PAH,-2.38367,0.520039,0.00175694,0.997078 beta-lactamase_39_F228E,beta-lactamase_39_228,TEM-1,beta-lactamase_39,P62593,0.99708,NO,228,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-2.342,-3.551,1.209,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.0495842,0.0046669,0.99708 kka2_1:4_S11S,kka2_1:4_11,Kka2,kka2_1:4,P00552,0.997082,NO,11,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.322,-2.322,,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.168804,0.00381691,0.997082 kka2_1:2_F20F,kka2_1:2_20,Kka2,kka2_1:2,P00552,0.997084,NO,20,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-3.354,-3.354,,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.295029,0.00701744,0.997084 beta-lactamase_625_R91K,beta-lactamase_625_91,TEM-1,beta-lactamase_625,P62593,0.997085,NO,91,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.392,-2.505,1.113,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.213352,0.00380226,0.997085 beta-lactamase_156_R273V,beta-lactamase_156_273,TEM-1,beta-lactamase_156,P62593,0.997091,NO,273,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.314,-3.626,1.312,,0.564,H,A,1.2,1.57,20.248,20.248,73.78,ABP,-1.841,0.111618,0.0077952,0.997091 beta-lactamase_39_R273V,beta-lactamase_39_273,TEM-1,beta-lactamase_39,P62593,0.997094,NO,273,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.314,-3.626,1.312,,0.564,H,A,1.2,1.57,2.163,,73.78,ABP,-1.841,0.0495842,0.0077952,0.997094 kka2_1:2_A25S,kka2_1:2_25,Kka2,kka2_1:2,P00552,0.997094,NO,25,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.496,-2.739,0.243,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.295029,0.00595636,0.997094 kka2_1:4_A172A,kka2_1:4_172,Kka2,kka2_1:4,P00552,0.997096,NO,172,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.757,-1.757,,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.168804,0.0079265,0.997096 beta-lactamase_39_K286L,beta-lactamase_39_286,TEM-1,beta-lactamase_39,P62593,0.997102,NO,286,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.0495842,,0.997102 beta-lactamase_625_Q37V,beta-lactamase_625_37,TEM-1,beta-lactamase_625,P62593,0.997102,NO,37,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.134,-3.664,1.53,,0.613,H,A,0.64,1.98,1.318,,73.08,APH,-2.06967,0.213352,0.00425833,0.997102 beta-lactamase_625_A185S,beta-lactamase_625_185,TEM-1,beta-lactamase_625,P62593,0.997103,NO,185,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.406,-3.291,1.885,,,H,A,0.46,-1.02,0.365,,65.03,HHP,-1.84033,0.213352,0.00467449,0.997103 beta-lactamase_0_V29G,beta-lactamase_0_29,TEM-1,beta-lactamase_0,P62593,0.997104,NO,29,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-2.856,-2.66,-0.196,,0.733,H,A,0.44,-0.78,21.916,21.916,93.01,HHB,-2.24733,0.0500837,0.00318969,0.997104 beta-lactamase_156_N50Y,beta-lactamase_156_50,TEM-1,beta-lactamase_156,P62593,0.997104,NO,50,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-2.979,-4.3,1.321,,0.912,T,A,0.61,1.24,13.295,13.295,77.62,HPP,-2.134,0.111618,0.0047211,0.997104 beta-lactamase_625_T263A,beta-lactamase_625_263,TEM-1,beta-lactamase_625,P62593,0.997104,NO,263,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.213352,0.0110582,0.997104 beta-lactamase_2500_H24A,beta-lactamase_2500_24,TEM-1,beta-lactamase_2500,P62593,0.997105,NO,24,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-2.481,-2.265,-0.216,,,,,,,0.467,,93.01,OBO,-2.0035,0.361275,0.00238894,0.997105 hsp90_F583Y,hsp90_583,hsp90,hsp90,P02829,0.997105,NO,583,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-3.22,-3.316,0,5.28185,1.112,S,l,1.1,0.87,,,,PHO,-3.003,0.368192,0.000222939,0.997105 beta-lactamase_39_N173E,beta-lactamase_39_173,TEM-1,beta-lactamase_39,P62593,0.997106,NO,173,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-2.663,-3.453,0.79,,1.044,T,l,0.61,1.25,1.426,,77.62,OPA,-1.46633,0.0495842,0.0033769,0.997106 beta-lactamase_2500_R189Y,beta-lactamase_2500_189,TEM-1,beta-lactamase_2500,P62593,0.997109,NO,189,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.844,-3.134,1.29,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.361275,0.0050699,0.997109 beta-lactamase_625_R275M,beta-lactamase_625_275,TEM-1,beta-lactamase_625,P62593,0.997109,NO,275,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.213352,0.0141984,0.997109 beta-lactamase_39_N173I,beta-lactamase_39_173,TEM-1,beta-lactamase_39,P62593,0.997111,NO,173,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-2.663,-4.172,1.509,,1.044,T,l,0.61,1.25,1.426,,77.62,OPA,-1.46633,0.0495842,0.0033769,0.997111 beta-lactamase_39_L197T,beta-lactamase_39_197,TEM-1,beta-lactamase_39,P62593,0.997112,NO,197,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.853,-3.419,2.566,,0.007,S,B,0.55,0.33,1.559,,60.14,HHP,-1.833,0.0495842,0.00144602,0.997112 beta-lactamase_625_S122Y,beta-lactamase_625_122,TEM-1,beta-lactamase_625,P62593,0.997112,NO,122,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.406,-4.156,1.75,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.213352,0.00497825,0.997112 hsp90_Q582F,hsp90_582,hsp90,hsp90,P02829,0.997113,NO,582,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-3.278,-3.22,0,4.91603,0.453,S,B,,0.67,,,,OPH,-3.249,0.368192,0.000222939,0.997113 beta-lactamase_39_L219T,beta-lactamase_39_219,TEM-1,beta-lactamase_39,P62593,0.997114,NO,219,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.313,-3.55,2.237,,,I,A,0.55,-0.51,19.842,19.842,74.48,HHB,-1.21533,0.0495842,0.00664345,0.997114 beta-lactamase_2500_S221C,beta-lactamase_2500_221,TEM-1,beta-lactamase_2500,P62593,0.997117,NO,221,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.754,-3.097,1.343,,0.624,H,A,0.27,-0.2,1.971,,74.48,BPH,-1.59967,0.361275,0.0046094,0.997117 beta-lactamase_625_L167T,beta-lactamase_625_167,TEM-1,beta-lactamase_625,P62593,0.997119,NO,167,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.138,-3.44,2.302,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.213352,0.00303566,0.997119 beta-lactamase_625_E102G,beta-lactamase_625_102,TEM-1,beta-lactamase_625,P62593,0.997123,NO,102,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.118,-2.728,0.61,,0.722,S,B,1.04,1.82,1.336,,73.08,HAH,-1.581,0.213352,0.00486633,0.997123 beta-lactamase_39_G281M,beta-lactamase_39_281,TEM-1,beta-lactamase_39,P62593,0.997125,NO,281,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.0495842,0.0406482,0.997125 beta-lactamase_156_G85E,beta-lactamase_156_85,TEM-1,beta-lactamase_156,P62593,0.997128,NO,85,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.011,-3.408,2.397,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.111618,0.00252173,0.997128 beta-lactamase_156_T269Q,beta-lactamase_156_269,TEM-1,beta-lactamase_156,P62593,0.997131,NO,269,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.111618,0.00950944,0.997131 beta-lactamase_156_D83S,beta-lactamase_156_83,TEM-1,beta-lactamase_156,P62593,0.997132,NO,83,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.066,-2.542,1.476,,0.354,H,A,0.75,0.22,1.281,,48.95,HAH,-1.34733,0.111618,0.00205968,0.997132 beta-lactamase_156_D83Q,beta-lactamase_156_83,TEM-1,beta-lactamase_156,P62593,0.997133,NO,83,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.066,-3.681,2.615,,0.354,H,A,0.75,0.22,1.281,,48.95,HAH,-1.34733,0.111618,0.00205968,0.997133 beta-lactamase_156_L49T,beta-lactamase_156_49,TEM-1,beta-lactamase_156,P62593,0.997133,NO,49,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.897,-1.853,-0.044,,0.131,T,A,0.55,0.04,3.112,,64.69,AHP,-1.99233,0.111618,0.00401477,0.997133 beta-lactamase_156_N173Q,beta-lactamase_156_173,TEM-1,beta-lactamase_156,P62593,0.997135,NO,173,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-2.663,-4.003,1.34,,1.044,T,l,0.61,1.25,3.718,,77.62,OPA,-1.46633,0.111618,0.0033769,0.997135 beta-lactamase_S96L,beta-lactamase_96,TEM-1,beta-lactamase,P62593,0.997135,NO,96,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.27,-3.527,1.257,5.29889,0.368,,b,0.25,0.39,32.348,32.348,73.78,HPP,-2.019,0.221079,0.00551835,0.997135 beta-lactamase_625_E145S,beta-lactamase_625_145,TEM-1,beta-lactamase_625,P62593,0.997136,NO,145,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.357,-2.669,0.312,,0.545,H,A,1.04,0.79,2.64,,77.62,BAH,-2.069,0.213352,0.00553285,0.997136 beta-lactamase_625_P25G,beta-lactamase_625_25,TEM-1,beta-lactamase_625,P62593,0.997137,NO,25,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.526,-2.198,0.672,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.213352,0.00347571,0.997137 beta-lactamase_156_N134Q,beta-lactamase_156_134,TEM-1,beta-lactamase_156,P62593,0.997144,NO,134,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-0.879,-3.672,2.793,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.111618,0.000644786,0.997144 beta-lactamase_625_L111D,beta-lactamase_625_111,TEM-1,beta-lactamase_625,P62593,0.997154,NO,111,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.76,-3.995,2.235,,0.328,T,A,0.55,0.93,2.26,,64.34,BHP,-1.884,0.213352,0.00480671,0.997154 beta-lactamase_0_I245R,beta-lactamase_0_245,TEM-1,beta-lactamase_0,P62593,0.997156,NO,245,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.0500837,0.00391032,0.997156 beta-lactamase_39_E102S,beta-lactamase_39_102,TEM-1,beta-lactamase_39,P62593,0.997159,NO,102,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.118,-2.129,0.011,,0.722,S,B,1.04,1.82,3.87,,73.08,HAH,-1.581,0.0495842,0.00486633,0.997159 beta-lactamase_156_R63M,beta-lactamase_156_63,TEM-1,beta-lactamase_156,P62593,0.99716,NO,63,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-0.943,-4.402,3.459,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.111618,0.00126938,0.99716 hsp90_E590I,hsp90_590,hsp90,hsp90,P02829,0.99716,NO,590,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.818,-2.939,0,4.65049,0.021,H,A,,0.03,,,,HAO,-3.338,0.368192,0.000222939,0.99716 beta-lactamase_D269V,beta-lactamase_269,TEM-1,beta-lactamase,P62593,0.997161,NO,269,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.156,-2.949,0.793,5.47645,0.646,H,A,0.23,0.4,21.796,21.796,77.62,HAA,-1.96733,0.221079,0.00950944,0.997161 beta-lactamase_625_E166Q,beta-lactamase_625_166,TEM-1,beta-lactamase_625,P62593,0.997164,NO,166,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.756,-3.022,1.266,,0.508,G,A,1.04,1.05,2.124,,73.08,OAH,-1.42233,0.213352,0.00512989,0.997164 beta-lactamase_156_A77R,beta-lactamase_156_77,TEM-1,beta-lactamase_156,P62593,0.997166,NO,77,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.234,-3.891,2.657,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.111618,0.00282362,0.997166 kka2_1:1_D5Y,kka2_1:1_5,Kka2,kka2_1:1,P00552,0.997166,NO,5,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.306,-4.118,2.812,,,,,,,0.895,,71.59,PAO,-1.784,0.520039,0.00222864,0.997166 beta-lactamase_2500_A84M,beta-lactamase_2500_84,TEM-1,beta-lactamase_2500,P62593,0.997167,NO,84,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.651,-4.707,3.056,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.361275,0.00503822,0.997167 beta-lactamase_156_T187I,beta-lactamase_156_187,TEM-1,beta-lactamase_156,P62593,0.997179,NO,187,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.401,-2.871,1.47,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.111618,0.00491782,0.997179 beta-lactamase_39_L89E,beta-lactamase_39_89,TEM-1,beta-lactamase_39,P62593,0.99718,NO,89,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.096,-3.801,2.705,,0.168,T,A,0.55,0.63,3.233,,64.34,PHO,-1.75767,0.0495842,0.00207068,0.99718 Pab1_K180R,Pab1_180,Pab1,Pab1,P04147,0.997183,NO,180,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.945,-2.41,0.465,,,,,,,,,,HBA,-1.575,0.175299,0.00295933,0.997183 beta-lactamase_2500_K144H,beta-lactamase_2500_144,TEM-1,beta-lactamase_2500,P62593,0.997185,NO,144,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-2.388,-3.395,1.007,,0.863,H,A,2.34,1.27,0.515,,77.62,OBA,-1.904,0.361275,0.00481141,0.997185 PSD95pdz3_K380I,PSD95pdz3_380,PSD95pdz3,PSD95pdz3,P31016,0.997188,NO,380,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.416,-3.692,2.276,5.87979,,,,,19.6722,,,,HBP,-1.391,0.0758425,0.000281399,0.997188 beta-lactamase_2500_A268G,beta-lactamase_2500_268,TEM-1,beta-lactamase_2500,P62593,0.997189,NO,268,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.361275,0.0102525,0.997189 PSD95pdz3_A343Q,PSD95pdz3_343,PSD95pdz3,PSD95pdz3,P31016,0.997192,NO,343,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.307,-3.581,2.274,5.585,,,,,14.728,,,,HHO,-1.22067,0.0758425,0.000798084,0.997192 kka2_1:8_R258H,kka2_1:8_258,Kka2,kka2_1:8,P00552,0.997195,NO,258,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.626,-4.623,2.997,,0.316,H,A,0.16,-0.85,5.58,,53.03,HBH,-1.25933,0.100394,0.00983174,0.997195 kka2_1:8_R258H,kka2_1:8_258,Kka2,kka2_1:8,P00552,0.997195,NO,258,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.626,-4.623,2.997,,0.316,H,A,0.16,-0.85,5.58,,53.03,HBH,-1.25933,0.100394,0.00983174,0.997195 beta-lactamase_156_T147Q,beta-lactamase_156_147,TEM-1,beta-lactamase_156,P62593,0.997197,NO,147,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.149,-3.979,2.83,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.111618,0.00226017,0.997197 Pab1_T159L,Pab1_159,Pab1,Pab1,P04147,0.997202,NO,159,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.445,-2.238,0.793,,,,,,,2.531,,79.03,HPA,-1.19467,0.175299,0.00133849,0.997202 beta-lactamase_156_P25T,beta-lactamase_156_25,TEM-1,beta-lactamase_156,P62593,0.997203,NO,25,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.526,-3.483,1.957,,0.624,H,A,0.52,0.14,1.079,,73.08,BOA,-2.15367,0.111618,0.00347571,0.997203 beta-lactamase_39_A34P,beta-lactamase_39_34,TEM-1,beta-lactamase_39,P62593,0.997203,NO,34,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.059,-4.024,1.965,,,H,A,0.46,-0.54,13.292,13.292,73.78,AHA,-1.74967,0.0495842,0.00407913,0.997203 beta-lactamase_39_V29R,beta-lactamase_39_29,TEM-1,beta-lactamase_39,P62593,0.997209,NO,29,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-2.856,-3.682,0.826,,0.733,H,A,0.44,-0.78,1.287,,93.01,HHB,-2.24733,0.0495842,0.00318969,0.997209 beta-lactamase_39_V29E,beta-lactamase_39_29,TEM-1,beta-lactamase_39,P62593,0.997219,NO,29,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-2.856,-1.855,-1.001,,0.733,H,A,0.44,-0.78,1.287,,93.01,HHB,-2.24733,0.0495842,0.00318969,0.997219 beta-lactamase_D269H,beta-lactamase_269,TEM-1,beta-lactamase,P62593,0.99722,NO,269,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.156,-4.646,2.49,5.47645,0.646,H,A,0.23,0.4,21.796,21.796,77.62,HAA,-1.96733,0.221079,0.00950944,0.99722 beta-lactamase_I206C,beta-lactamase_206,TEM-1,beta-lactamase,P62593,0.99722,NO,206,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-2.429,-4.969,2.54,5.3727,0.173,H,A,1,-0.34,2.061,,77.62,HHA,-1.805,0.221079,0.00528934,0.99722 beta-lactamase_K144F,beta-lactamase_144,TEM-1,beta-lactamase,P62593,0.99722,NO,144,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-2.388,-4.427,2.039,6.02507,0.863,H,A,2.81,1.27,0.515,,77.62,OBA,-1.904,0.221079,0.00481141,0.99722 beta-lactamase_K284Q,beta-lactamase_284,TEM-1,beta-lactamase,P62593,0.99722,NO,284,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.981,-2.496,0.515,6.30084,0.848,H,A,1.82,0.67,1.931,,77.62,HBB,-1.82133,0.221079,0.0686156,0.99722 beta-lactamase_M180N,beta-lactamase_180,TEM-1,beta-lactamase,P62593,0.99722,NO,180,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-2.795,-3.603,0.808,4.96809,0.242,,B,1.07,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.221079,0.00552048,0.99722 beta-lactamase_P20N,beta-lactamase_20,TEM-1,beta-lactamase,P62593,0.99722,NO,20,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.74,-3.859,2.119,,,,,,,0.368,,67.83,HOH,-1.765,0.221079,0.00235322,0.99722 beta-lactamase_Q203S,beta-lactamase_203,TEM-1,beta-lactamase,P62593,0.99722,NO,203,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.168,-2.824,0.656,5.65296,0.47,H,A,0.12,-0.38,1.66,,65.38,BPP,-1.614,0.221079,0.00631514,0.99722 beta-lactamase_R189R,beta-lactamase_189,TEM-1,beta-lactamase,P62593,0.99722,NO,189,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.844,-1.844,,5.74877,0.278,H,A,0.68,1.01,1.512,,72.73,HBB,-1.668,0.221079,0.0050699,0.99722 beta-lactamase_R273A,beta-lactamase_273,TEM-1,beta-lactamase,P62593,0.99722,NO,273,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.314,-1.856,-0.458,,0.564,H,A,1.2,1.57,,,73.78,ABP,-1.841,0.221079,0.0077952,0.99722 beta-lactamase_S281R,beta-lactamase_281,TEM-1,beta-lactamase,P62593,0.99722,NO,281,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.247,-3.921,1.674,4.73591,0.128,H,A,0.25,-0.26,2.144,,77.62,HPH,-1.847,0.221079,0.0406482,0.99722 kka2_1:1_E3E,kka2_1:1_3,Kka2,kka2_1:1,P00552,0.997221,NO,3,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.199,-2.199,,,,,,,,3.435,,92.05,HAP,-2.11567,0.520039,0.00267607,0.997221 beta-lactamase_156_H94Q,beta-lactamase_156_94,TEM-1,beta-lactamase_156,P62593,0.997223,NO,94,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-2.5,-3.155,0.655,,0.776,,B,0.17,1.24,11.583,11.583,77.62,HBH,-1.872,0.111618,0.00389226,0.997223 beta-lactamase_39_I140S,beta-lactamase_39_140,TEM-1,beta-lactamase_39,P62593,0.997223,NO,140,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.733,-3.688,1.955,,0.128,H,A,0.48,0.41,1.16,,73.08,PHO,-1.48733,0.0495842,0.00597777,0.997223 beta-lactamase_39_Y103C,beta-lactamase_39_103,TEM-1,beta-lactamase_39,P62593,0.997223,NO,103,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-1.33,-5.047,3.717,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.0495842,0.00443048,0.997223 beta-lactamase_156_V214C,beta-lactamase_156_214,TEM-1,beta-lactamase_156,P62593,0.997226,NO,214,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.299,-4.725,3.426,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.111618,0.00628442,0.997226 beta-lactamase_625_K53F,beta-lactamase_625_53,TEM-1,beta-lactamase_625,P62593,0.997227,NO,53,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-2.313,-4.249,1.936,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.213352,0.00383383,0.997227 beta-lactamase_39_P60A,beta-lactamase_39_60,TEM-1,beta-lactamase_39,P62593,0.997228,NO,60,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-2.469,-1.436,-1.033,,0.256,T,A,0.52,-0.56,21.37,21.37,77.62,BOA,-1.97633,0.0495842,0.00521318,0.997228 kka2_1:8_T85S,kka2_1:8_85,Kka2,kka2_1:8,P00552,0.997228,NO,85,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.165,-2.241,0.076,,0.576,E,B,0.22,1.39,22.154,22.154,71.59,HPA,-2.10133,0.100394,0.00634493,0.997228 kka2_1:8_T85S,kka2_1:8_85,Kka2,kka2_1:8,P00552,0.997228,NO,85,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.165,-2.241,0.076,,0.576,E,B,0.22,1.39,22.154,22.154,71.59,HPA,-2.10133,0.100394,0.00634493,0.997228 beta-lactamase_156_I140G,beta-lactamase_156_140,TEM-1,beta-lactamase_156,P62593,0.997229,NO,140,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.733,-3.828,2.095,,0.128,H,A,0.48,0.41,1.16,,73.08,PHO,-1.48733,0.111618,0.00597777,0.997229 beta-lactamase_2500_Q86K,beta-lactamase_2500_86,TEM-1,beta-lactamase_2500,P62593,0.997229,NO,86,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.4,-2.554,0.154,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.361275,0.00450027,0.997229 Pab1_H172H,Pab1_172,Pab1,Pab1,P04147,0.997232,NO,172,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-1.21,-1.21,,,0.076,E,B,0.35,-0.87,,,,HBH,-1.26667,0.175299,0.000296642,0.997232 beta-lactamase_625_L55R,beta-lactamase_625_55,TEM-1,beta-lactamase_625,P62593,0.997233,NO,55,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.86,-3.1,1.24,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.213352,0.00403741,0.997233 beta-lactamase_2500_K53A,beta-lactamase_2500_53,TEM-1,beta-lactamase_2500,P62593,0.997238,NO,53,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-2.313,-2.735,0.422,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.361275,0.00383383,0.997238 beta-lactamase_625_A182I,beta-lactamase_625_182,TEM-1,beta-lactamase_625,P62593,0.997241,NO,182,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.777,-3.851,2.074,,0.136,H,A,0.46,-0.66,16.784,16.784,93.01,OHH,-1.27367,0.213352,0.00559099,0.997241 beta-lactamase_625_G154R,beta-lactamase_625_154,TEM-1,beta-lactamase_625,P62593,0.997241,NO,154,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.823,-3.969,3.146,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.213352,0.00180205,0.997241 gb1_T244W,gb1_244,gb1,gb1,P06654,0.997241,NO,244,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.637,-5.015,3.378,,,,,,,0.202,,11.83,PPA,-1.92567,0.177985,0.00222755,0.997241 beta-lactamase_2500_S122L,beta-lactamase_2500_122,TEM-1,beta-lactamase_2500,P62593,0.997245,NO,122,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.406,-2.918,0.512,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.361275,0.00497825,0.997245 beta-lactamase_625_S57W,beta-lactamase_625_57,TEM-1,beta-lactamase_625,P62593,0.997245,NO,57,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.918,-5.449,3.531,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.213352,0.00492804,0.997245 beta-lactamase_156_R41E,beta-lactamase_156_41,TEM-1,beta-lactamase_156,P62593,0.99725,NO,41,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-0.942,-3.241,2.299,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.111618,0.00123327,0.99725 beta-lactamase_2500_N152K,beta-lactamase_2500_152,TEM-1,beta-lactamase_2500,P62593,0.997251,NO,152,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-2.757,-2.892,0.135,,0.863,H,A,0.61,0.92,2.061,,77.62,BPH,-2.97,0.361275,0.00471429,0.997251 kka2_1:2_E160E,kka2_1:2_160,Kka2,kka2_1:2,P00552,0.997255,NO,160,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.683,-1.683,,,0.989,G,A,1.04,2.28,3.948,,71.59,AAA,-1.36133,0.295029,0.00935762,0.997255 kka2_1:2_R173R,kka2_1:2_173,Kka2,kka2_1:2,P00552,0.997255,NO,173,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.407,-2.407,,,0.308,H,A,0.16,-0.13,15.389,15.389,65.53,HBH,-1.70533,0.295029,0.00784999,0.997255 beta-lactamase_2500_E145G,beta-lactamase_2500_145,TEM-1,beta-lactamase_2500,P62593,0.99726,NO,145,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.357,-1.279,-1.078,,0.545,H,A,1.04,0.79,2.124,,77.62,BAH,-2.069,0.361275,0.00553285,0.99726 beta-lactamase_625_I171W,beta-lactamase_625_171,TEM-1,beta-lactamase_625,P62593,0.997265,NO,171,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-2.431,-5.376,2.945,,0.361,,B,0.48,0.53,3.869,,77.62,HHO,-1.55533,0.213352,0.00623355,0.997265 beta-lactamase_39_K30G,beta-lactamase_39_30,TEM-1,beta-lactamase_39,P62593,0.997269,NO,30,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-2.307,-3.406,1.099,,0.142,H,A,2.34,-0.65,6.717,,93.01,HBH,-2.32833,0.0495842,0.00448593,0.997269 beta-lactamase_156_K30V,beta-lactamase_156_30,TEM-1,beta-lactamase_156,P62593,0.997275,NO,30,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-2.307,-2.807,0.5,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.111618,0.00448593,0.997275 beta-lactamase_156_Q86R,beta-lactamase_156_86,TEM-1,beta-lactamase_156,P62593,0.997276,NO,86,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.4,-2.686,0.286,,0.696,S,A,0.64,2.38,27.704,27.704,77.62,OPA,-1.61067,0.111618,0.00450027,0.997276 beta-lactamase_625_S57H,beta-lactamase_625_57,TEM-1,beta-lactamase_625,P62593,0.997278,NO,57,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.918,-3.329,1.411,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.213352,0.00492804,0.997278 beta-lactamase_156_A215Q,beta-lactamase_156_215,TEM-1,beta-lactamase_156,P62593,0.997288,NO,215,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.503,-2.998,1.495,,,,a,0.46,-0.93,3.583,,74.48,HHO,-1.42633,0.111618,0.00544007,0.997288 beta-lactamase_625_D207W,beta-lactamase_625_207,TEM-1,beta-lactamase_625,P62593,0.997288,NO,207,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.064,-5.493,3.429,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.213352,0.00592942,0.997288 beta-lactamase_2500_Y262M,beta-lactamase_2500_262,TEM-1,beta-lactamase_2500,P62593,0.997289,NO,262,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.361275,0.00853516,0.997289 beta-lactamase_625_S266M,beta-lactamase_625_266,TEM-1,beta-lactamase_625,P62593,0.997292,NO,266,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.213352,0.0140785,0.997292 PSD95pdz3_G383F,PSD95pdz3_383,PSD95pdz3,PSD95pdz3,P31016,0.997294,NO,383,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.008,-3.974,2.966,5.17213,,,,,20.5325,,,,HOP,-1.338,0.0758425,0.000233044,0.997294 beta-lactamase_39_A268H,beta-lactamase_39_268,TEM-1,beta-lactamase_39,P62593,0.997296,NO,268,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.0495842,0.0102525,0.997296 beta-lactamase_39_A84S,beta-lactamase_39_84,TEM-1,beta-lactamase_39,P62593,0.997298,NO,84,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.651,-2.609,0.958,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.0495842,0.00503822,0.997298 PSD95pdz3_D348A,PSD95pdz3_348,PSD95pdz3,PSD95pdz3,P31016,0.997298,NO,348,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.264,-2.984,1.72,5.02473,,,,,16.8925,,,,HAH,-1.306,0.0758425,0.000731866,0.997298 beta-lactamase_625_L160A,beta-lactamase_625_160,TEM-1,beta-lactamase_625,P62593,0.997299,NO,160,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.977,-3.094,2.117,,0.022,,B,0.55,-0.6,0.237,,44.41,BHA,-0.936,0.213352,0.00193775,0.997299 beta-lactamase_39_G240C,beta-lactamase_39_240,TEM-1,beta-lactamase_39,P62593,0.9973,NO,240,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.0495842,0.00591201,0.9973 beta-lactamase_156_L218T,beta-lactamase_156_218,TEM-1,beta-lactamase_156,P62593,0.99731,NO,218,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.391,-2.536,1.145,,,I,b,0.55,-0.53,17.202,17.202,74.48,OHH,-1.58867,0.111618,0.00618274,0.99731 kka2_1:2_D90H,kka2_1:2_90,Kka2,kka2_1:2,P00552,0.997311,NO,90,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.459,-2.113,-0.346,,0.104,E,B,0.75,0.73,6.085,,64.39,BAH,-1.72833,0.295029,0.00583842,0.997311 beta-lactamase_39_E102Q,beta-lactamase_39_102,TEM-1,beta-lactamase_39,P62593,0.997312,NO,102,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.118,-3.043,0.925,,0.722,S,B,1.04,1.82,3.87,,73.08,HAH,-1.581,0.0495842,0.00486633,0.997312 beta-lactamase_156_H94G,beta-lactamase_156_94,TEM-1,beta-lactamase_156,P62593,0.997315,NO,94,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-2.5,-3.593,1.093,,0.776,,B,0.17,1.24,11.583,11.583,77.62,HBH,-1.872,0.111618,0.00389226,0.997315 beta-lactamase_625_V214L,beta-lactamase_625_214,TEM-1,beta-lactamase_625,P62593,0.997318,NO,214,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.299,-2.237,0.938,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.213352,0.00628442,0.997318 beta-lactamase_39_F58Y,beta-lactamase_39_58,TEM-1,beta-lactamase_39,P62593,0.997319,NO,58,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-2.914,-1.89,-1.024,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.0495842,0.00523369,0.997319 beta-lactamase_39_H156E,beta-lactamase_39_156,TEM-1,beta-lactamase_39,P62593,0.997319,NO,156,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-3.156,-2.577,-0.579,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.0495842,0.00468596,0.997319 beta-lactamase_156_G253L,beta-lactamase_156_253,TEM-1,beta-lactamase_156,P62593,0.997323,NO,253,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.111618,0.00786358,0.997323 beta-lactamase_625_A182C,beta-lactamase_625_182,TEM-1,beta-lactamase_625,P62593,0.997323,NO,182,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.777,-5.025,3.248,,0.136,H,A,0.46,-0.66,16.784,16.784,93.01,OHH,-1.27367,0.213352,0.00559099,0.997323 beta-lactamase_2500_A182E,beta-lactamase_2500_182,TEM-1,beta-lactamase_2500,P62593,0.997328,NO,182,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.777,-2.345,0.568,,0.136,H,A,0.46,-0.66,2.032,,93.01,OHH,-1.27367,0.361275,0.00559099,0.997328 beta-lactamase_156_A225V,beta-lactamase_156_225,TEM-1,beta-lactamase_156,P62593,0.997329,NO,225,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.845,-3.655,1.81,,1,T,B,0.46,-0.38,11.722,11.722,74.48,OHO,-1.39967,0.111618,0.00465057,0.997329 beta-lactamase_156_Q267G,beta-lactamase_156_267,TEM-1,beta-lactamase_156,P62593,0.997329,NO,267,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.111618,0.0102128,0.997329 beta-lactamase_2500_L196S,beta-lactamase_2500_196,TEM-1,beta-lactamase_2500,P62593,0.997329,NO,196,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-2.478,-2.752,0.274,,0.518,S,A,0.55,1.35,7.897,,77.62,AHH,-1.839,0.361275,0.00512144,0.997329 beta-lactamase_2500_Q37V,beta-lactamase_2500_37,TEM-1,beta-lactamase_2500,P62593,0.997333,NO,37,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.134,-3.664,1.53,,0.613,H,A,0.64,1.98,1.318,,73.08,APH,-2.06967,0.361275,0.00425833,0.997333 beta-lactamase_625_E175S,beta-lactamase_625_175,TEM-1,beta-lactamase_625,P62593,0.99734,NO,175,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.336,-2.863,0.527,,0.551,,A,1.04,1.05,8.527,8.527,77.62,AAB,-1.31233,0.213352,0.00482205,0.99734 beta-lactamase_156_D99E,beta-lactamase_156_99,TEM-1,beta-lactamase_156,P62593,0.997344,NO,99,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.191,-2.122,0.931,,0.402,G,A,0.75,0.36,3.529,,64.69,PAH,-1.794,0.111618,0.00305446,0.997344 beta-lactamase_156_K144G,beta-lactamase_156_144,TEM-1,beta-lactamase_156,P62593,0.997346,NO,144,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-2.388,-2.818,0.43,,0.863,H,A,2.34,1.27,2.073,,77.62,OBA,-1.904,0.111618,0.00481141,0.997346 beta-lactamase_39_S256V,beta-lactamase_39_256,TEM-1,beta-lactamase_39,P62593,0.997347,NO,256,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.0495842,0.00710634,0.997347 E1_Ubiquitin_K48F,E1_Ubiquitin_48,Uba1,E1_Ubiquitin,P0CG63,0.997347,NO,48,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.219,-4.162,2.943,,0.132,E,B,,-0.28,,,,OBO,-1.109,0.18783,0.00100363,0.997347 E1_Ubiquitin_R74I,E1_Ubiquitin_74,Uba1,E1_Ubiquitin,P0CG63,0.997347,NO,74,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.302,-3.881,2.579,,0.838,T,A,,3.15,,,,HBO,-1.11333,0.18783,0.00180798,0.997347 kka2_1:2_E231E,kka2_1:2_231,Kka2,kka2_1:2,P00552,0.997347,NO,231,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.002,-2.002,,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.295029,0.00732383,0.997347 beta-lactamase_156_R275Y,beta-lactamase_156_275,TEM-1,beta-lactamase_156,P62593,0.997356,NO,275,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.111618,0.0141984,0.997356 beta-lactamase_625_N168Q,beta-lactamase_625_168,TEM-1,beta-lactamase_625,P62593,0.997359,NO,168,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-1.029,-3.749,2.72,,0.113,G,A,0.61,-0.4,1.014,,44.41,HPA,-1.13233,0.213352,0.00288667,0.997359 kka2_1:1_S251S,kka2_1:1_251,Kka2,kka2_1:1,P00552,0.997359,NO,251,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.636,-2.636,,,0.712,H,A,0.27,-0.25,1.356,,71.59,APP,-2.09367,0.520039,0.0138916,0.997359 beta-lactamase_625_G76C,beta-lactamase_625_76,TEM-1,beta-lactamase_625,P62593,0.99736,NO,76,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.189,-4.823,3.634,,,H,A,0.29,-0.67,3.059,,67.83,OOH,-1.22267,0.213352,0.00476637,0.99736 beta-lactamase_39_A278G,beta-lactamase_39_278,TEM-1,beta-lactamase_39,P62593,0.997361,NO,278,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.0495842,0.0310297,0.997361 PSD95pdz3_R312A,PSD95pdz3_312,PSD95pdz3,PSD95pdz3,P31016,0.997361,NO,312,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.582,-2.759,1.177,5.76826,,,,,12.2409,,,,OBB,-1.46667,0.0758425,0.00196255,0.997361 beta-lactamase_625_R159Y,beta-lactamase_625_159,TEM-1,beta-lactamase_625,P62593,0.997364,NO,159,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-0.94,-4.035,3.095,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.213352,0.00108472,0.997364 beta-lactamase_156_G216C,beta-lactamase_156_216,TEM-1,beta-lactamase_156,P62593,0.997365,NO,216,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.477,-5.186,3.709,,0.437,I,A,0.29,-0.58,12.464,12.464,74.48,HOO,-1.68067,0.111618,0.00639568,0.997365 beta-lactamase_625_A247S,beta-lactamase_625_247,TEM-1,beta-lactamase_625,P62593,0.997369,NO,247,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.213352,0.00611275,0.997369 beta-lactamase_A34V,beta-lactamase_34,TEM-1,beta-lactamase,P62593,0.997369,NO,34,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.059,-2.227,0.168,4.9129,,H,A,0.75,-0.54,3.614,,73.78,AHA,-1.74967,0.221079,0.00407913,0.997369 beta-lactamase_2500_A268L,beta-lactamase_2500_268,TEM-1,beta-lactamase_2500,P62593,0.99737,NO,268,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.361275,0.0102525,0.99737 beta-lactamase_39_P172F,beta-lactamase_39_172,TEM-1,beta-lactamase_39,P62593,0.997371,NO,172,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.998,-4.371,3.373,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.0495842,0.00312594,0.997371 beta-lactamase_625_L28S,beta-lactamase_625_28,TEM-1,beta-lactamase_625,P62593,0.997374,NO,28,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.579,-3.523,1.944,,0.277,H,A,0.55,-0.16,2.716,,93.01,PHH,-2.11333,0.213352,0.00359321,0.997374 beta-lactamase_2500_D252H,beta-lactamase_2500_252,TEM-1,beta-lactamase_2500,P62593,0.997378,NO,252,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.94,,,,0.766,,B,1.59,1.16,,,67.83,OAO,-2.0965,0.361275,0.00575769,0.997378 beta-lactamase_625_Q267L,beta-lactamase_625_267,TEM-1,beta-lactamase_625,P62593,0.997379,NO,267,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.213352,0.0102128,0.997379 beta-lactamase_E169K,beta-lactamase_169,TEM-1,beta-lactamase,P62593,0.99738,NO,169,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.23,-3.226,1.996,5.78896,0.337,,A,0.52,1,1.806,,73.08,PAH,-1.16533,0.221079,0.00400994,0.99738 beta-lactamase_39_T126F,beta-lactamase_39_126,TEM-1,beta-lactamase_39,P62593,0.997383,NO,126,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.122,-4.199,3.077,,0.05,H,A,0.22,-0.05,0.586,,44.41,HPH,-1.60467,0.0495842,0.00244552,0.997383 beta-lactamase_625_A170V,beta-lactamase_625_170,TEM-1,beta-lactamase_625,P62593,0.997386,NO,170,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.237,-2.64,1.403,,0.126,,L,0.46,-0.35,3.626,,64.69,AHH,-1.63267,0.213352,0.00431903,0.997386 beta-lactamase_156_P143C,beta-lactamase_156_143,TEM-1,beta-lactamase_156,P62593,0.997388,NO,143,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.967,-5.012,4.045,,0.075,H,A,0.52,-0.37,0.479,,66.78,OOB,-1.354,0.111618,0.00114551,0.997388 beta-lactamase_39_G253E,beta-lactamase_39_253,TEM-1,beta-lactamase_39,P62593,0.997393,NO,253,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.0495842,0.00786358,0.997393 beta-lactamase_39_K286I,beta-lactamase_39_286,TEM-1,beta-lactamase_39,P62593,0.997396,NO,286,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.0495842,,0.997396 beta-lactamase_156_A34C,beta-lactamase_156_34,TEM-1,beta-lactamase_156,P62593,0.997397,NO,34,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.059,-4.764,2.705,,,H,A,0.46,-0.54,3.614,,73.78,AHA,-1.74967,0.111618,0.00407913,0.997397 beta-lactamase_0_G76A,beta-lactamase_0_76,TEM-1,beta-lactamase_0,P62593,0.997404,NO,76,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.189,-1.531,0.342,,,H,A,0.29,-0.67,1.188,,67.83,OOH,-1.22267,0.0500837,0.00476637,0.997404 beta-lactamase_39_L74T,beta-lactamase_39_74,TEM-1,beta-lactamase_39,P62593,0.997405,NO,74,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.296,-3.432,2.136,,,H,A,0.55,-0.91,1.581,,50,HHO,-1.34933,0.0495842,0.00493255,0.997405 gb1_D272Y,gb1_272,gb1,gb1,P06654,0.997405,NO,272,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.457,-4.134,2.677,,,,,,,0.234,,11.83,HAA,-1.54533,0.177985,0.00218257,0.997405 gb1_K236C,gb1_236,gb1,gb1,P06654,0.997405,NO,236,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-2.119,-4.781,2.662,,,,,,,1.083,,45.54,OBP,-1.758,0.177985,0.00255408,0.997405 gb1_K236F,gb1_236,gb1,gb1,P06654,0.997405,NO,236,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-2.119,-4.126,2.007,,,,,,,1.083,,45.54,OBP,-1.758,0.177985,0.00255408,0.997405 beta-lactamase_625_E279Y,beta-lactamase_625_279,TEM-1,beta-lactamase_625,P62593,0.997406,NO,279,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.213352,0.0192826,0.997406 Pab1_E176R,Pab1_176,Pab1,Pab1,P04147,0.997406,NO,176,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.003,-3.773,1.77,,,,,,,,,,AAO,-2.09933,0.175299,0.00264426,0.997406 beta-lactamase_Q88Y,beta-lactamase_88,TEM-1,beta-lactamase,P62593,0.997411,NO,88,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.086,-4.349,2.263,5.8056,0.807,,B,0.12,2.03,1.84,,77.62,APH,-1.53433,0.221079,0.00504167,0.997411 kka2_1:8_M197I,kka2_1:8_197,Kka2,kka2_1:8,P00552,0.997411,NO,197,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.707,-1.88,0.173,,0.121,E,B,1.59,-1.19,4.408,,65.53,HHH,-1.847,0.100394,0.00921295,0.997411 kka2_1:8_M197I,kka2_1:8_197,Kka2,kka2_1:8,P00552,0.997411,NO,197,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.707,-1.88,0.173,,0.121,E,B,1.59,-1.19,4.408,,65.53,HHH,-1.847,0.100394,0.00921295,0.997411 beta-lactamase_156_L219T,beta-lactamase_156_219,TEM-1,beta-lactamase_156,P62593,0.997415,NO,219,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.313,-3.55,2.237,,,I,A,0.55,-0.51,2.321,,74.48,HHB,-1.21533,0.111618,0.00664345,0.997415 beta-lactamase_156_W163K,beta-lactamase_156_163,TEM-1,beta-lactamase_156,P62593,0.997415,NO,163,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-1.843,-2.971,1.128,,0.467,,B,0.47,-0.5,15.095,15.095,63.99,BHA,-1.269,0.111618,0.00418955,0.997415 beta-lactamase_625_P217G,beta-lactamase_625_217,TEM-1,beta-lactamase_625,P62593,0.997416,NO,217,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-2.062,-2.748,0.686,,0.496,I,A,0.52,-0.33,1.087,,74.48,OOH,-1.64333,0.213352,0.00463211,0.997416 beta-lactamase_625_L160M,beta-lactamase_625_160,TEM-1,beta-lactamase_625,P62593,0.997417,NO,160,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.977,-3.902,2.925,,0.022,,B,0.55,-0.6,0.237,,44.41,BHA,-0.936,0.213352,0.00193775,0.997417 kka2_1:2_V16V,kka2_1:2_16,Kka2,kka2_1:2,P00552,0.997417,NO,16,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-3.087,-3.087,,,0.742,T,A,0.44,0.34,1.746,,71.59,HHA,-2.211,0.295029,0.00694011,0.997417 beta-lactamase_625_G85W,beta-lactamase_625_85,TEM-1,beta-lactamase_625,P62593,0.99742,NO,85,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.011,-5.288,4.277,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.213352,0.00252173,0.99742 beta-lactamase_156_R162A,beta-lactamase_156_162,TEM-1,beta-lactamase_156,P62593,0.997421,NO,162,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.016,-3.127,2.111,,0.124,S,B,1.2,-0.37,7.444,,64.69,ABH,-1.25,0.111618,0.000561334,0.997421 beta-lactamase_2500_N173E,beta-lactamase_2500_173,TEM-1,beta-lactamase_2500,P62593,0.997423,NO,173,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-2.663,-3.453,0.79,,1.044,T,l,0.61,1.25,1.88,,77.62,OPA,-1.46633,0.361275,0.0033769,0.997423 Pab1_F173F,Pab1_173,Pab1,Pab1,P04147,0.997424,NO,173,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.477,-1.477,,,,E,B,0.87,-0.16,1.636,,63.26,BHA,-1.36967,0.175299,0.00148779,0.997424 kka2_1:2_M197Q,kka2_1:2_197,Kka2,kka2_1:2,P00552,0.997426,NO,197,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.707,-4.152,2.445,,0.121,E,B,0.55,-1.19,2.097,,65.53,HHH,-1.847,0.295029,0.00921295,0.997426 beta-lactamase_156_I229M,beta-lactamase_156_229,TEM-1,beta-lactamase_156,P62593,0.997428,NO,229,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.267,-4.125,2.858,,0.083,E,B,0.48,-0.76,1.114,,50,HHH,-1.58767,0.111618,0.00477249,0.997428 beta-lactamase_39_N134H,beta-lactamase_39_134,TEM-1,beta-lactamase_39,P62593,0.997432,NO,134,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-0.879,-4.073,3.194,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.0495842,0.000644786,0.997432 beta-lactamase_39_G240Q,beta-lactamase_39_240,TEM-1,beta-lactamase_39,P62593,0.997436,NO,240,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.0495842,0.00591201,0.997436 beta-lactamase_39_S57A,beta-lactamase_39_57,TEM-1,beta-lactamase_39,P62593,0.997447,NO,57,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.918,-1.894,-0.024,,0.352,E,B,0.27,-0.18,2.3,,72.73,APH,-2.29167,0.0495842,0.00492804,0.997447 beta-lactamase_39_R81C,beta-lactamase_39_81,TEM-1,beta-lactamase_39,P62593,0.997449,NO,81,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.466,-5.147,3.681,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.0495842,0.00499763,0.997449 beta-lactamase_625_L199T,beta-lactamase_625_199,TEM-1,beta-lactamase_625,P62593,0.997453,NO,199,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-2.942,-2.763,-0.179,,0.832,H,A,0.55,0.42,1.552,,77.62,PHH,-2.32933,0.213352,0.0048649,0.997453 kka2_1:4_G6G,kka2_1:4_6,Kka2,kka2_1:4,P00552,0.997453,NO,6,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.685,-1.685,,,,,,,,,,71.59,AOH,-1.639,0.168804,0.00204693,0.997453 beta-lactamase_39_P250D,beta-lactamase_39_250,TEM-1,beta-lactamase_39,P62593,0.997454,NO,250,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-2.335,-1.83,-0.505,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.0495842,0.00550899,0.997454 kka2_1:2_A248A,kka2_1:2_248,Kka2,kka2_1:2,P00552,0.997455,NO,248,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.124,-2.124,,,0.825,S,b,0.46,0.46,,,92.05,HHO,-2.15,0.295029,0.0125484,0.997455 beta-lactamase_625_L199I,beta-lactamase_625_199,TEM-1,beta-lactamase_625,P62593,0.997456,NO,199,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-2.942,-3.16,0.218,,0.832,H,A,0.55,0.42,1.552,,77.62,PHH,-2.32933,0.213352,0.0048649,0.997456 beta-lactamase_39_R176S,beta-lactamase_39_176,TEM-1,beta-lactamase_39,P62593,0.997457,NO,176,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-0.863,-3.386,2.523,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.0495842,0.00105554,0.997457 beta-lactamase_Q88F,beta-lactamase_88,TEM-1,beta-lactamase,P62593,0.997457,NO,88,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.086,-4.377,2.291,5.8056,0.807,,B,0.12,2.03,1.84,,77.62,APH,-1.53433,0.221079,0.00504167,0.997457 beta-lactamase_625_T269G,beta-lactamase_625_269,TEM-1,beta-lactamase_625,P62593,0.997458,NO,269,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.213352,0.00950944,0.997458 beta-lactamase_625_L55C,beta-lactamase_625_55,TEM-1,beta-lactamase_625,P62593,0.99746,NO,55,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.86,-4.909,3.049,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.213352,0.00403741,0.99746 beta-lactamase_625_A222P,beta-lactamase_625_222,TEM-1,beta-lactamase_625,P62593,0.997465,NO,222,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.103,-2.971,0.868,,0.233,H,A,0.46,-0.25,1.448,,77.62,PHH,-1.63733,0.213352,0.00466094,0.997465 beta-lactamase_0_G194N,beta-lactamase_0_194,TEM-1,beta-lactamase_0,P62593,0.997467,NO,194,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.396,-2.573,1.177,,0.276,S,b,0.29,0.36,3.017,,67.83,POA,-1.832,0.0500837,0.00392163,0.997467 beta-lactamase_0_R162S,beta-lactamase_0_162,TEM-1,beta-lactamase_0,P62593,0.997468,NO,162,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.016,-3.456,2.44,,0.124,S,B,1.2,-0.37,1.026,,64.69,ABH,-1.25,0.0500837,0.000561334,0.997468 beta-lactamase_156_D207M,beta-lactamase_156_207,TEM-1,beta-lactamase_156,P62593,0.997468,NO,207,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.064,-4.822,2.758,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.111618,0.00592942,0.997468 kka2_1:4_A65Y,kka2_1:4_65,Kka2,kka2_1:4,P00552,0.997471,NO,65,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.744,-4.354,2.61,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.168804,0.00709258,0.997471 beta-lactamase_39_I245F,beta-lactamase_39_245,TEM-1,beta-lactamase_39,P62593,0.997476,NO,245,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.0495842,0.00391032,0.997476 beta-lactamase_39_R189V,beta-lactamase_39_189,TEM-1,beta-lactamase_39,P62593,0.997477,NO,189,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.844,-3.783,1.939,,0.278,H,A,1.2,1.01,12.11,12.11,72.73,HBB,-1.668,0.0495842,0.0050699,0.997477 beta-lactamase_39_N274V,beta-lactamase_39_274,TEM-1,beta-lactamase_39,P62593,0.997482,NO,274,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.0495842,0.0110418,0.997482 beta-lactamase_2500_K254R,beta-lactamase_2500_254,TEM-1,beta-lactamase_2500,P62593,0.997483,NO,254,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.361275,0.00369,0.997483 beta-lactamase_39_R159V,beta-lactamase_39_159,TEM-1,beta-lactamase_39,P62593,0.997483,NO,159,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-0.94,-3.779,2.839,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.0495842,0.00108472,0.997483 beta-lactamase_156_P255H,beta-lactamase_156_255,TEM-1,beta-lactamase_156,P62593,0.997488,NO,255,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.111618,0.00499612,0.997488 kka2_1:1_V242M,kka2_1:1_242,Kka2,kka2_1:1,P00552,0.997488,NO,242,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-2.687,-4.779,2.092,,0.75,H,A,0.44,-0.37,4.987,,71.59,HHH,-2.16533,0.520039,0.0102575,0.997488 beta-lactamase_39_P250L,beta-lactamase_39_250,TEM-1,beta-lactamase_39,P62593,0.99749,NO,250,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.0495842,0.00550899,0.99749 beta-lactamase_625_N50E,beta-lactamase_625_50,TEM-1,beta-lactamase_625,P62593,0.99749,NO,50,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-2.979,-2.315,-0.664,,0.912,T,A,0.61,1.24,3.446,,77.62,HPP,-2.134,0.213352,0.0047211,0.99749 beta-lactamase_625_A132S,beta-lactamase_625_132,TEM-1,beta-lactamase_625,P62593,0.997493,NO,132,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.9,-2.411,1.511,,,H,A,0.46,-0.93,0.316,,64.69,PHH,-1.138,0.213352,0.000962524,0.997493 beta-lactamase_156_E166P,beta-lactamase_156_166,TEM-1,beta-lactamase_156,P62593,0.997494,NO,166,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.756,-3.897,2.141,,0.508,G,A,1.04,1.05,2.393,,73.08,OAH,-1.42233,0.111618,0.00512989,0.997494 beta-lactamase_0_E56S,beta-lactamase_0_56,TEM-1,beta-lactamase_0,P62593,0.997499,NO,56,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.043,-2.169,0.126,,0.198,E,B,1.04,0.31,1.491,,72.73,HAP,-1.94033,0.0500837,0.00238534,0.997499 beta-lactamase_H151L,beta-lactamase_151,TEM-1,beta-lactamase,P62593,0.997508,NO,151,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-2.96,-3.494,0.534,5.47408,0.594,H,A,0.35,0.1,1.843,,77.62,HBP,-2.34767,0.221079,0.00216946,0.997508 beta-lactamase_625_T193L,beta-lactamase_625_193,TEM-1,beta-lactamase_625,P62593,0.997509,NO,193,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.914,-1.776,-0.138,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.213352,0.00482669,0.997509 beta-lactamase_625_S80R,beta-lactamase_625_80,TEM-1,beta-lactamase_625,P62593,0.99751,NO,80,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.029,-3.076,1.047,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.213352,0.00565569,0.99751 beta-lactamase_156_S241G,beta-lactamase_156_241,TEM-1,beta-lactamase_156,P62593,0.997512,NO,241,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.111618,0.00452736,0.997512 kka2_1:2_A172A,kka2_1:2_172,Kka2,kka2_1:2,P00552,0.997512,NO,172,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.757,-1.757,,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.295029,0.0079265,0.997512 beta-lactamase_2500_N50T,beta-lactamase_2500_50,TEM-1,beta-lactamase_2500,P62593,0.997518,NO,50,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-2.979,-2.678,-0.301,,0.912,T,A,0.61,1.24,1.581,,77.62,HPP,-2.134,0.361275,0.0047211,0.997518 beta-lactamase_156_Q37G,beta-lactamase_156_37,TEM-1,beta-lactamase_156,P62593,0.997519,NO,37,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.134,-3.507,1.373,,0.613,H,A,0.64,1.98,12.052,12.052,73.08,APH,-2.06967,0.111618,0.00425833,0.997519 beta-lactamase_156_M184L,beta-lactamase_156_184,TEM-1,beta-lactamase_156,P62593,0.997528,NO,184,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.593,-2.806,1.213,,,H,A,0.55,-0.87,1.671,,62.94,HHH,-1.41,0.111618,0.00356019,0.997528 beta-lactamase_Q97Q,beta-lactamase_97,TEM-1,beta-lactamase,P62593,0.99753,NO,97,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.072,-2.072,,6.30204,0.823,G,A,1.1,2.42,1.157,,77.62,PPP,-2.43833,0.221079,0.0045116,0.99753 beta-lactamase_2500_L196D,beta-lactamase_2500_196,TEM-1,beta-lactamase_2500,P62593,0.997531,NO,196,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-2.478,-3.862,1.384,,0.518,S,A,0.55,1.35,7.897,,77.62,AHH,-1.839,0.361275,0.00512144,0.997531 beta-lactamase_39_L219P,beta-lactamase_39_219,TEM-1,beta-lactamase_39,P62593,0.997533,NO,219,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.313,-4.214,2.901,,,I,A,0.55,-0.51,19.842,19.842,74.48,HHB,-1.21533,0.0495842,0.00664345,0.997533 beta-lactamase_625_D174E,beta-lactamase_625_174,TEM-1,beta-lactamase_625,P62593,0.997533,NO,174,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.738,-2.765,2.027,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.213352,0.00125633,0.997533 beta-lactamase_156_P172A,beta-lactamase_156_172,TEM-1,beta-lactamase_156,P62593,0.997536,NO,172,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.998,-2.44,1.442,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.111618,0.00312594,0.997536 beta-lactamase_156_T178C,beta-lactamase_156_178,TEM-1,beta-lactamase_156,P62593,0.997537,NO,178,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-0.791,-4.637,3.846,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.111618,0.000684366,0.997537 beta-lactamase_156_G216S,beta-lactamase_156_216,TEM-1,beta-lactamase_156,P62593,0.997538,NO,216,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.477,-3.283,1.806,,0.437,I,A,0.29,-0.58,12.464,12.464,74.48,HOO,-1.68067,0.111618,0.00639568,0.997538 beta-lactamase_156_T186L,beta-lactamase_156_186,TEM-1,beta-lactamase_156,P62593,0.99754,NO,186,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.522,-2.882,0.36,,0.396,H,A,0.22,-0.28,16.606,16.606,77.62,HPP,-1.77633,0.111618,0.00485034,0.99754 beta-lactamase_39_P217S,beta-lactamase_39_217,TEM-1,beta-lactamase_39,P62593,0.997546,NO,217,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-2.062,-2.615,0.553,,0.496,I,A,0.52,-0.33,21.172,21.172,74.48,OOH,-1.64333,0.0495842,0.00463211,0.997546 beta-lactamase_156_P172N,beta-lactamase_156_172,TEM-1,beta-lactamase_156,P62593,0.997547,NO,172,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.998,-3.875,2.877,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.111618,0.00312594,0.997547 Pab1_D136F,Pab1_136,Pab1,Pab1,P04147,0.997548,NO,136,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.602,-4.055,2.453,,,,,,,,,,OAH,-1.42367,0.175299,0.00227029,0.997548 beta-lactamase_625_P217L,beta-lactamase_625_217,TEM-1,beta-lactamase_625,P62593,0.997549,NO,217,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-2.062,-3.634,1.572,,0.496,I,A,0.52,-0.33,1.087,,74.48,OOH,-1.64333,0.213352,0.00463211,0.997549 beta-lactamase_156_G281M,beta-lactamase_156_281,TEM-1,beta-lactamase_156,P62593,0.99755,NO,281,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.111618,0.0406482,0.99755 beta-lactamase_156_K32R,beta-lactamase_156_32,TEM-1,beta-lactamase_156,P62593,0.99755,NO,32,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.984,-2.38,0.396,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.111618,0.00401283,0.99755 kka2_1:2_E149E,kka2_1:2_149,Kka2,kka2_1:2,P00552,0.99755,NO,149,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.994,-1.994,,,0.674,H,A,1.04,1.63,15.361,15.361,71.59,HAH,-1.59667,0.295029,0.00803343,0.99755 beta-lactamase_625_K286Q,beta-lactamase_625_286,TEM-1,beta-lactamase_625,P62593,0.997553,NO,286,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.213352,,0.997553 beta-lactamase_156_L284E,beta-lactamase_156_284,TEM-1,beta-lactamase_156,P62593,0.997555,NO,284,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.111618,0.0686156,0.997555 beta-lactamase_39_K30W,beta-lactamase_39_30,TEM-1,beta-lactamase_39,P62593,0.997557,NO,30,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-2.307,-5.404,3.097,,0.142,H,A,2.34,-0.65,6.717,,93.01,HBH,-2.32833,0.0495842,0.00448593,0.997557 beta-lactamase_0_V29L,beta-lactamase_0_29,TEM-1,beta-lactamase_0,P62593,0.99756,NO,29,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-2.856,-3.547,0.691,,0.733,H,A,0.44,-0.78,21.916,21.916,93.01,HHB,-2.24733,0.0500837,0.00318969,0.99756 beta-lactamase_156_G226Y,beta-lactamase_156_226,TEM-1,beta-lactamase_156,P62593,0.997565,NO,226,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.461,-4.462,3.001,,0.701,T,l,0.29,-0.25,3.199,,74.48,HOH,-1.42933,0.111618,0.00665294,0.997565 beta-lactamase_625_A235L,beta-lactamase_625_235,TEM-1,beta-lactamase_625,P62593,0.997567,NO,235,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.266,-3.325,2.059,,0.32,E,B,0.46,-0.86,0.281,,50,OHO,-0.89,0.213352,0.00493474,0.997567 gb1_K236Q,gb1_236,gb1,gb1,P06654,0.997568,NO,236,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-2.119,-2.334,0.215,,,,,,,1.083,,45.54,OBP,-1.758,0.177985,0.00255408,0.997568 kka2_1:4_V242V,kka2_1:4_242,Kka2,kka2_1:4,P00552,0.997568,NO,242,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-2.687,-2.687,,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.168804,0.0102575,0.997568 beta-lactamase_39_I244N,beta-lactamase_39_244,TEM-1,beta-lactamase_39,P62593,0.997571,NO,244,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.555,-4.114,2.559,,,E,B,0.48,-0.84,1.325,,77.62,OHH,-1.385,0.0495842,0.00605379,0.997571 beta-lactamase_2500_L196E,beta-lactamase_2500_196,TEM-1,beta-lactamase_2500,P62593,0.997572,NO,196,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-2.478,-3.033,0.555,,0.518,S,A,0.55,1.35,7.897,,77.62,AHH,-1.839,0.361275,0.00512144,0.997572 PSD95pdz3_L349S,PSD95pdz3_349,PSD95pdz3,PSD95pdz3,P31016,0.997578,NO,349,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.347,-3.292,1.945,5.14696,,,,,24.6438,,,,AHP,-1.37667,0.0758425,0.00071841,0.997578 beta-lactamase_2500_L111M,beta-lactamase_2500_111,TEM-1,beta-lactamase_2500,P62593,0.99758,NO,111,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.76,-4.22,2.46,,0.328,T,A,0.55,0.93,1.966,,64.34,BHP,-1.884,0.361275,0.00480671,0.99758 beta-lactamase_625_S256Q,beta-lactamase_625_256,TEM-1,beta-lactamase_625,P62593,0.997586,NO,256,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.213352,0.00710634,0.997586 beta-lactamase_H156R,beta-lactamase_156,TEM-1,beta-lactamase,P62593,0.997587,NO,156,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-3.156,-2.742,-0.414,6.00284,0.753,S,A,0.72,-0.6,6.456,6.456,77.62,ABH,-1.932,0.221079,0.00468596,0.997587 beta-lactamase_R118F,beta-lactamase_118,TEM-1,beta-lactamase,P62593,0.997587,NO,118,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.413,-4.338,1.925,5.8227,0.457,H,A,0.68,1.39,2.144,,77.62,HBA,-1.785,0.221079,0.00538794,0.997587 beta-lactamase_156_Q88D,beta-lactamase_156_88,TEM-1,beta-lactamase_156,P62593,0.997588,NO,88,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.086,-2.035,-0.051,,0.807,,B,0.64,2.03,0.911,,77.62,APH,-1.53433,0.111618,0.00504167,0.997588 beta-lactamase_39_W163A,beta-lactamase_39_163,TEM-1,beta-lactamase_39,P62593,0.997589,NO,163,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-1.843,-3.41,1.567,,0.467,,B,0.47,-0.5,15.095,15.095,63.99,BHA,-1.269,0.0495842,0.00418955,0.997589 kka2_1:8_G210A,kka2_1:8_210,Kka2,kka2_1:8,P00552,0.997593,NO,210,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.095,-2.003,0.908,,0.103,T,A,0.75,-0.62,2.687,,50,OOB,-0.966667,0.100394,0.00598378,0.997593 kka2_1:8_G210A,kka2_1:8_210,Kka2,kka2_1:8,P00552,0.997593,NO,210,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.095,-2.003,0.908,,0.103,T,A,0.75,-0.62,2.687,,50,OOB,-0.966667,0.100394,0.00598378,0.997593 beta-lactamase_625_A235T,beta-lactamase_625_235,TEM-1,beta-lactamase_625,P62593,0.997594,NO,235,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.266,-2.412,1.146,,0.32,E,B,0.46,-0.86,0.281,,50,OHO,-0.89,0.213352,0.00493474,0.997594 beta-lactamase_625_E166T,beta-lactamase_625_166,TEM-1,beta-lactamase_625,P62593,0.997595,NO,166,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.756,-2.857,1.101,,0.508,G,A,1.04,1.05,2.124,,73.08,OAH,-1.42233,0.213352,0.00512989,0.997595 beta-lactamase_625_M184L,beta-lactamase_625_184,TEM-1,beta-lactamase_625,P62593,0.997601,NO,184,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.593,-2.806,1.213,,,H,A,0.55,-0.87,2.765,,62.94,HHH,-1.41,0.213352,0.00356019,0.997601 kka2_1:4_A176A,kka2_1:4_176,Kka2,kka2_1:4,P00552,0.997604,NO,176,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.621,-1.621,,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.168804,0.0083587,0.997604 beta-lactamase_39_G154V,beta-lactamase_39_154,TEM-1,beta-lactamase_39,P62593,0.997609,NO,154,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.823,-3.725,2.902,,0.54,T,l,0.29,-0.56,1.151,,64.69,HOA,-1.635,0.0495842,0.00180205,0.997609 beta-lactamase_156_T264K,beta-lactamase_156_264,TEM-1,beta-lactamase_156,P62593,0.997611,NO,264,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.111618,0.0119399,0.997611 beta-lactamase_156_T264E,beta-lactamase_156_264,TEM-1,beta-lactamase_156,P62593,0.997616,NO,264,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.111618,0.0119399,0.997616 beta-lactamase_2500_D271I,beta-lactamase_2500_271,TEM-1,beta-lactamase_2500,P62593,0.997616,NO,271,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.361275,0.00752082,0.997616 beta-lactamase_625_A247Y,beta-lactamase_625_247,TEM-1,beta-lactamase_625,P62593,0.99762,NO,247,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.213352,0.00611275,0.99762 beta-lactamase_0_A211V,beta-lactamase_0_211,TEM-1,beta-lactamase_0,P62593,0.997624,NO,211,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.896,-3.651,1.755,,0.369,T,A,0.46,-0.69,8.527,8.527,77.62,AHA,-1.94633,0.0500837,0.00648183,0.997624 beta-lactamase_625_F149D,beta-lactamase_625_149,TEM-1,beta-lactamase_625,P62593,0.997624,NO,149,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.299,-3.957,2.658,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.213352,0.00418462,0.997624 beta-lactamase_625_R176N,beta-lactamase_625_176,TEM-1,beta-lactamase_625,P62593,0.997624,NO,176,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-0.863,-3.448,2.585,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.213352,0.00105554,0.997624 kka2_1:8_T72A,kka2_1:8_72,Kka2,kka2_1:8,P00552,0.997624,NO,72,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.38,-2.118,-0.262,,0.784,H,A,0.22,0.29,3.603,,65.53,HPP,-2.238,0.100394,0.00750756,0.997624 kka2_1:8_T72A,kka2_1:8_72,Kka2,kka2_1:8,P00552,0.997624,NO,72,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.38,-2.118,-0.262,,0.784,H,A,0.22,0.29,3.603,,65.53,HPP,-2.238,0.100394,0.00750756,0.997624 kka2_1:8_D154M,kka2_1:8_154,Kka2,kka2_1:8,P00552,0.997626,NO,154,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.876,-4.959,4.083,,0.457,,b,0.29,1.48,0.844,,52.65,HAP,-1.52467,0.100394,0.00292633,0.997626 kka2_1:8_D154M,kka2_1:8_154,Kka2,kka2_1:8,P00552,0.997626,NO,154,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.876,-4.959,4.083,,0.457,,b,0.29,1.48,0.844,,52.65,HAP,-1.52467,0.100394,0.00292633,0.997626 kka2_1:8_V153Q,kka2_1:8_153,Kka2,kka2_1:8,P00552,0.997626,NO,153,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.092,-4.272,3.18,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.100394,0.00501119,0.997626 kka2_1:8_V153Q,kka2_1:8_153,Kka2,kka2_1:8,P00552,0.997626,NO,153,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.092,-4.272,3.18,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.100394,0.00501119,0.997626 beta-lactamase_0_G281Q,beta-lactamase_0_281,TEM-1,beta-lactamase_0,P62593,0.99763,NO,281,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.0500837,0.0406482,0.99763 beta-lactamase_0_R81I,beta-lactamase_0_81,TEM-1,beta-lactamase_0,P62593,0.997635,NO,81,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.466,-4.004,2.538,,0.218,H,A,1.2,1.66,0.332,,50,PBH,-1.60667,0.0500837,0.00499763,0.997635 beta-lactamase_2500_T193C,beta-lactamase_2500_193,TEM-1,beta-lactamase_2500,P62593,0.997635,NO,193,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.914,-4.857,2.943,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.361275,0.00482669,0.997635 beta-lactamase_39_A123C,beta-lactamase_39_123,TEM-1,beta-lactamase_39,P62593,0.997636,NO,123,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.834,-4.461,3.627,,0.039,H,A,0.46,-0.72,0.705,,41.26,PHH,-1.47367,0.0495842,0.0010157,0.997636 beta-lactamase_39_I140W,beta-lactamase_39_140,TEM-1,beta-lactamase_39,P62593,0.997637,NO,140,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.733,-5.289,3.556,,0.128,H,A,0.48,0.41,1.16,,73.08,PHO,-1.48733,0.0495842,0.00597777,0.997637 beta-lactamase_625_R118Y,beta-lactamase_625_118,TEM-1,beta-lactamase_625,P62593,0.997637,NO,118,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.413,-4.398,1.985,,0.457,H,A,1.2,1.39,2.144,,77.62,HBA,-1.785,0.213352,0.00538794,0.997637 beta-lactamase_39_L137G,beta-lactamase_39_137,TEM-1,beta-lactamase_39,P62593,0.997642,NO,137,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.03,-3.837,2.807,,,H,A,0.55,-0.38,0.674,,42.31,HHP,-1.58933,0.0495842,0.00278599,0.997642 beta-lactamase_2500_K254S,beta-lactamase_2500_254,TEM-1,beta-lactamase_2500,P62593,0.997643,NO,254,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-2.126,-3.446,1.32,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.361275,0.00369,0.997643 beta-lactamase_156_A183Y,beta-lactamase_156_183,TEM-1,beta-lactamase_156,P62593,0.997645,NO,183,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.231,-4.261,3.03,,0.155,H,A,0.46,-0.91,23.859,23.859,77.62,HHH,-1.53367,0.111618,0.00296631,0.997645 beta-lactamase_625_T193A,beta-lactamase_625_193,TEM-1,beta-lactamase_625,P62593,0.997645,NO,193,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.914,-2.618,0.704,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.213352,0.00482669,0.997645 beta-lactamase_156_E46F,beta-lactamase_156_46,TEM-1,beta-lactamase_156,P62593,0.997647,NO,46,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.94,-4.056,2.116,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.111618,0.00427568,0.997647 Pab1_N192T,Pab1_192,Pab1,Pab1,P04147,0.997648,NO,192,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-1.079,-3.014,1.935,,0.619,T,l,,2.28,,,,HPO,-1.231,0.175299,0.000273498,0.997648 Pab1_Y143H,Pab1_143,Pab1,Pab1,P04147,0.997651,NO,143,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-1.961,-1.533,-0.428,,0.409,H,A,,0.3,,,,HHA,-1.39633,0.175299,0.00160364,0.997651 beta-lactamase_625_Q88C,beta-lactamase_625_88,TEM-1,beta-lactamase_625,P62593,0.997656,NO,88,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.086,-5.138,3.052,,0.807,,B,0.64,2.03,1.84,,77.62,APH,-1.53433,0.213352,0.00504167,0.997656 beta-lactamase_0_P143W,beta-lactamase_0_143,TEM-1,beta-lactamase_0,P62593,0.997662,NO,143,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.967,-5.497,4.53,,0.075,H,A,0.52,-0.37,11.868,11.868,66.78,OOB,-1.354,0.0500837,0.00114551,0.997662 beta-lactamase_156_T187L,beta-lactamase_156_187,TEM-1,beta-lactamase_156,P62593,0.997663,NO,187,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.401,-2.278,0.877,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.111618,0.00491782,0.997663 beta-lactamase_156_I54A,beta-lactamase_156_54,TEM-1,beta-lactamase_156,P62593,0.997669,NO,54,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-2.838,-2.597,-0.241,,0.669,E,B,0.48,-0.14,0.541,,73.78,BHH,-2.337,0.111618,0.00403589,0.997669 beta-lactamase_K53L,beta-lactamase_53,TEM-1,beta-lactamase,P62593,0.99767,NO,53,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-2.313,-2.678,0.365,5.93654,0.589,,B,1.82,1.15,19.72,19.72,77.62,OBH,-2.1,0.221079,0.00383383,0.99767 beta-lactamase_39_A230C,beta-lactamase_39_230,TEM-1,beta-lactamase_39,P62593,0.997677,NO,230,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.154,-4.695,3.541,,0.01,E,B,0.46,-1.17,1.171,,50,HHA,-1.079,0.0495842,0.00516841,0.997677 beta-lactamase_625_K213F,beta-lactamase_625_213,TEM-1,beta-lactamase_625,P62593,0.997678,NO,213,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.81,-4.437,2.627,,0.67,,A,2.34,0.29,3.924,,67.83,ABH,-1.57767,0.213352,0.00610411,0.997678 kka2_1:2_Q163Q,kka2_1:2_163,Kka2,kka2_1:2,P00552,0.997683,NO,163,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.162,-2.162,,,0.58,T,B,0.64,1.85,3.888,,64.02,BPO,-1.78333,0.295029,0.00719507,0.997683 beta-lactamase_156_H156W,beta-lactamase_156_156,TEM-1,beta-lactamase_156,P62593,0.997687,NO,156,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-3.156,-5.55,2.394,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.111618,0.00468596,0.997687 beta-lactamase_625_R202L,beta-lactamase_625_202,TEM-1,beta-lactamase_625,P62593,0.997688,NO,202,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.292,-3.422,2.13,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.213352,0.00321899,0.997688 beta-lactamase_156_Q97R,beta-lactamase_156_97,TEM-1,beta-lactamase_156,P62593,0.997692,NO,97,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.072,-2.428,0.356,,0.823,G,A,0.64,2.42,4.457,,77.62,PPP,-2.43833,0.111618,0.0045116,0.997692 beta-lactamase_625_Q86I,beta-lactamase_625_86,TEM-1,beta-lactamase_625,P62593,0.997696,NO,86,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.4,-3.877,1.477,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.213352,0.00450027,0.997696 beta-lactamase_2500_A247V,beta-lactamase_2500_247,TEM-1,beta-lactamase_2500,P62593,0.997702,NO,247,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.361275,0.00611275,0.997702 beta-lactamase_625_T264K,beta-lactamase_625_264,TEM-1,beta-lactamase_625,P62593,0.997706,NO,264,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.213352,0.0119399,0.997706 beta-lactamase_156_A148M,beta-lactamase_156_148,TEM-1,beta-lactamase_156,P62593,0.997708,NO,148,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.757,-4.798,3.041,,0.379,H,A,0.46,-0.55,3.551,,72.73,PHH,-1.40167,0.111618,0.00547053,0.997708 kka2_1:4_C192V,kka2_1:4_192,Kka2,kka2_1:4,P00552,0.997708,NO,192,C,V,CV,Special,Hydrophobic,5.07,5.60847,0.538465,192,121,117,-4,108.5,140,31.5,-1.067,-3.41,2.343,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.168804,0.00485428,0.997708 beta-lactamase_625_L135M,beta-lactamase_625_135,TEM-1,beta-lactamase_625,P62593,0.997709,NO,135,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.002,-2.838,1.836,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.213352,0.00244423,0.997709 beta-lactamase_156_L89Y,beta-lactamase_156_89,TEM-1,beta-lactamase_156,P62593,0.997713,NO,89,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.096,-4.101,3.005,,0.168,T,A,0.55,0.63,2.633,,64.34,PHO,-1.75767,0.111618,0.00207068,0.997713 beta-lactamase_A200P,beta-lactamase_200,TEM-1,beta-lactamase,P62593,0.997715,NO,200,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.878,-2.581,0.703,5.19406,0.757,H,A,0.47,-0.19,0.436,,77.62,HHP,-2.001,0.221079,0.0060056,0.997715 beta-lactamase_156_A230V,beta-lactamase_156_230,TEM-1,beta-lactamase_156,P62593,0.997719,NO,230,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.154,-3.38,2.226,,0.01,E,B,0.46,-1.17,2.179,,50,HHA,-1.079,0.111618,0.00516841,0.997719 kka2_1:1_A168A,kka2_1:1_168,Kka2,kka2_1:1,P00552,0.997729,NO,168,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.989,-1.989,,,0.67,H,A,0.46,0.15,25.546,25.546,64.39,OHA,-2.12933,0.520039,0.00806773,0.997729 gb1_K239A,gb1_239,gb1,gb1,P06654,0.997731,NO,239,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-3.043,-2.72,-0.323,,,,,,,1.326,,45.54,HBO,-2.31467,0.177985,0.00207004,0.997731 gb1_T270E,gb1_270,gb1,gb1,P06654,0.997731,NO,270,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-3.15,-3.273,0.123,,,,,,,1.326,,45.54,HPH,-1.843,0.177985,0.00223707,0.997731 beta-lactamase_156_K254L,beta-lactamase_156_254,TEM-1,beta-lactamase_156,P62593,0.997736,NO,254,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.111618,0.00369,0.997736 beta-lactamase_625_M153W,beta-lactamase_625_153,TEM-1,beta-lactamase_625,P62593,0.997737,NO,153,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-3.193,-5.376,2.183,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.213352,0.00509109,0.997737 beta-lactamase_625_N173M,beta-lactamase_625_173,TEM-1,beta-lactamase_625,P62593,0.997737,NO,173,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-2.663,-4.901,2.238,,1.044,T,l,0.61,1.25,1.426,,77.62,OPA,-1.46633,0.213352,0.0033769,0.997737 beta-lactamase_39_G154I,beta-lactamase_39_154,TEM-1,beta-lactamase_39,P62593,0.99774,NO,154,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.823,-4.173,3.35,,0.54,T,l,0.29,-0.56,1.151,,64.69,HOA,-1.635,0.0495842,0.00180205,0.99774 beta-lactamase_39_G281V,beta-lactamase_39_281,TEM-1,beta-lactamase_39,P62593,0.99774,NO,281,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.0495842,0.0406482,0.99774 kka2_1:2_A168A,kka2_1:2_168,Kka2,kka2_1:2,P00552,0.99774,NO,168,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.989,-1.989,,,0.67,H,A,0.46,0.15,25.546,25.546,64.39,OHA,-2.12933,0.295029,0.00806773,0.99774 beta-lactamase_2500_M67N,beta-lactamase_2500_67,TEM-1,beta-lactamase_2500,P62593,0.997742,NO,67,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-2.231,-2.235,0.004,,0.006,G,P,0.55,-0.81,2.653,,65.03,HHP,-1.502,0.361275,0.00409753,0.997742 beta-lactamase_625_T107C,beta-lactamase_625_107,TEM-1,beta-lactamase_625,P62593,0.997742,NO,107,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.117,-4.664,3.547,,,G,A,0.22,-0.06,3.676,,67.83,HPA,-1.265,0.213352,0.00239347,0.997742 beta-lactamase_625_L219F,beta-lactamase_625_219,TEM-1,beta-lactamase_625,P62593,0.997747,NO,219,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.313,-2.825,1.512,,,I,A,0.55,-0.51,5.627,,74.48,HHB,-1.21533,0.213352,0.00664345,0.997747 beta-lactamase_R202S,beta-lactamase_202,TEM-1,beta-lactamase,P62593,0.99775,NO,202,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.292,-2.609,1.317,5.16273,0.188,H,A,0.68,0.62,1.918,,77.62,PBP,-1.54767,0.221079,0.00321899,0.99775 beta-lactamase_156_N50Q,beta-lactamase_156_50,TEM-1,beta-lactamase_156,P62593,0.997753,NO,50,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-2.979,-2.653,-0.326,,0.912,T,A,0.61,1.24,13.295,13.295,77.62,HPP,-2.134,0.111618,0.0047211,0.997753 beta-lactamase_625_L49V,beta-lactamase_625_49,TEM-1,beta-lactamase_625,P62593,0.997753,NO,49,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.897,-2.549,0.652,,0.131,T,A,0.55,0.04,3.112,,64.69,AHP,-1.99233,0.213352,0.00401477,0.997753 kka2_1:4_A56W,kka2_1:4_56,Kka2,kka2_1:4,P00552,0.997757,NO,56,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.083,-5.608,3.525,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.168804,0.00717715,0.997757 beta-lactamase_156_D36L,beta-lactamase_156_36,TEM-1,beta-lactamase_156,P62593,0.997758,NO,36,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.732,-3.628,0.896,,0.555,H,A,0.75,1.17,14.871,14.871,77.62,AAP,-1.91167,0.111618,0.00476483,0.997758 beta-lactamase_156_G226E,beta-lactamase_156_226,TEM-1,beta-lactamase_156,P62593,0.997759,NO,226,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.461,-2.776,1.315,,0.701,T,l,0.29,-0.25,3.199,,74.48,HOH,-1.42933,0.111618,0.00665294,0.997759 Pab1_S165H,Pab1_165,Pab1,Pab1,P04147,0.997763,NO,165,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.146,-4.272,3.126,,0.12,,a,,0.11,,,,BPB,-1.56867,0.175299,0.000307838,0.997763 beta-lactamase_2500_R275E,beta-lactamase_2500_275,TEM-1,beta-lactamase_2500,P62593,0.997768,NO,275,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.361275,0.0141984,0.997768 beta-lactamase_39_Q37R,beta-lactamase_39_37,TEM-1,beta-lactamase_39,P62593,0.99777,NO,37,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.134,-2.096,-0.038,,0.613,H,A,0.64,1.98,22.282,22.282,73.08,APH,-2.06967,0.0495842,0.00425833,0.99777 beta-lactamase_625_R81Y,beta-lactamase_625_81,TEM-1,beta-lactamase_625,P62593,0.997774,NO,81,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.466,-4.271,2.805,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.213352,0.00499763,0.997774 Pab1_Y143F,Pab1_143,Pab1,Pab1,P04147,0.997782,NO,143,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-1.961,-2.326,0.365,,0.409,H,A,,0.3,,,,HHA,-1.39633,0.175299,0.00160364,0.997782 PSD95pdz3_K393L,PSD95pdz3_393,PSD95pdz3,PSD95pdz3,P31016,0.997786,NO,393,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.416,-3.04,1.624,5.42682,,,,,22.0122,,,,HBO,-1.4265,0.0758425,0.000879298,0.997786 beta-lactamase_2500_E272V,beta-lactamase_2500_272,TEM-1,beta-lactamase_2500,P62593,0.997787,NO,272,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.361275,0.00545371,0.997787 beta-lactamase_156_A183Q,beta-lactamase_156_183,TEM-1,beta-lactamase_156,P62593,0.997789,NO,183,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.231,-3.932,2.701,,0.155,H,A,0.46,-0.91,23.859,23.859,77.62,HHH,-1.53367,0.111618,0.00296631,0.997789 kka2_1:8_K112M,kka2_1:8_112,Kka2,kka2_1:8,P00552,0.99779,NO,112,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-2.491,-4.49,1.999,,0.076,H,A,1.3,-1.37,10.58,10.58,56.06,ABH,-2.00133,0.100394,0.00645389,0.99779 kka2_1:8_K112M,kka2_1:8_112,Kka2,kka2_1:8,P00552,0.99779,NO,112,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-2.491,-4.49,1.999,,0.076,H,A,1.3,-1.37,10.58,10.58,56.06,ABH,-2.00133,0.100394,0.00645389,0.99779 beta-lactamase_39_P65G,beta-lactamase_39_65,TEM-1,beta-lactamase_39,P62593,0.997793,NO,65,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.894,-3.443,2.549,,0.098,E,B,0.52,-0.62,0.623,,40.56,HOH,-1.03233,0.0495842,0.00152776,0.997793 beta-lactamase_625_I125T,beta-lactamase_625_125,TEM-1,beta-lactamase_625,P62593,0.997793,NO,125,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.441,-2.752,1.311,,,H,A,0.48,-0.7,2.034,,63.29,HHP,-1.248,0.213352,0.00383964,0.997793 beta-lactamase_156_M127R,beta-lactamase_156_127,TEM-1,beta-lactamase_156,P62593,0.997796,NO,127,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-2.251,-2.722,0.471,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.111618,0.00437927,0.997796 kka2_1:4_A79A,kka2_1:4_79,Kka2,kka2_1:4,P00552,0.997799,NO,79,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.368,-2.368,,,0.563,.,B,0.46,-0.43,2.291,,71.59,HHH,-1.752,0.168804,0.00664821,0.997799 beta-lactamase_K53M,beta-lactamase_53,TEM-1,beta-lactamase,P62593,0.997802,NO,53,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-2.313,-4.641,2.328,5.93654,0.589,,B,1.82,1.15,19.72,19.72,77.62,OBH,-2.1,0.221079,0.00383383,0.997802 beta-lactamase_M127E,beta-lactamase_127,TEM-1,beta-lactamase,P62593,0.997802,NO,127,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-2.251,-3.04,0.789,5.40552,0.312,S,A,1.07,0.32,1.671,,72.73,PHP,-1.40433,0.221079,0.00437927,0.997802 kka2_1:2_A35A,kka2_1:2_35,Kka2,kka2_1:2,P00552,0.997803,NO,35,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.127,-2.127,,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.295029,0.00630016,0.997803 beta-lactamase_156_T269F,beta-lactamase_156_269,TEM-1,beta-lactamase_156,P62593,0.997806,NO,269,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.111618,0.00950944,0.997806 beta-lactamase_156_A84Y,beta-lactamase_156_84,TEM-1,beta-lactamase_156,P62593,0.997807,NO,84,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.651,-4.29,2.639,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.111618,0.00503822,0.997807 beta-lactamase_625_V259C,beta-lactamase_625_259,TEM-1,beta-lactamase_625,P62593,0.997811,NO,259,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.213352,0.0070773,0.997811 beta-lactamase_156_D113C,beta-lactamase_156_113,TEM-1,beta-lactamase_156,P62593,0.997812,NO,113,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.829,-5.156,3.327,,0.665,T,A,0.75,0.91,2.973,,73.08,PAO,-1.703,0.111618,0.00474112,0.997812 beta-lactamase_39_N50L,beta-lactamase_39_50,TEM-1,beta-lactamase_39,P62593,0.997813,NO,50,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-2.979,-2.892,-0.087,,0.912,T,A,0.61,1.24,10.736,,77.62,HPP,-2.134,0.0495842,0.0047211,0.997813 kka2_1:2_A247A,kka2_1:2_247,Kka2,kka2_1:2,P00552,0.997816,NO,247,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.459,-2.459,,,1.01,S,A,0.46,0.65,0.828,,92.05,HHH,-2.197,0.295029,0.0102428,0.997816 beta-lactamase_156_E62S,beta-lactamase_156_62,TEM-1,beta-lactamase_156,P62593,0.997818,NO,62,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.193,-3.245,2.052,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.111618,0.00264802,0.997818 beta-lactamase_0_E164V,beta-lactamase_0_164,TEM-1,beta-lactamase_0,P62593,0.997822,NO,164,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-0.948,-3.599,2.651,,0.011,T,B,1.04,-0.4,1.011,,64.69,HAO,-1.388,0.0500837,0.00137286,0.997822 beta-lactamase_625_G265T,beta-lactamase_625_265,TEM-1,beta-lactamase_625,P62593,0.997822,NO,265,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.213352,0.00811926,0.997822 beta-lactamase_156_L47F,beta-lactamase_156_47,TEM-1,beta-lactamase_156,P62593,0.997826,NO,47,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.876,-3.101,1.225,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.111618,0.00439844,0.997826 beta-lactamase_625_N173V,beta-lactamase_625_173,TEM-1,beta-lactamase_625,P62593,0.997828,NO,173,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-2.663,-3.738,1.075,,1.044,T,l,0.61,1.25,1.426,,77.62,OPA,-1.46633,0.213352,0.0033769,0.997828 beta-lactamase_156_E166N,beta-lactamase_156_166,TEM-1,beta-lactamase_156,P62593,0.99783,NO,166,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.756,-3.709,1.953,,0.508,G,A,1.04,1.05,2.393,,73.08,OAH,-1.42233,0.111618,0.00512989,0.99783 beta-lactamase_625_E238M,beta-lactamase_625_238,TEM-1,beta-lactamase_625,P62593,0.99783,NO,238,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.213352,0.00743256,0.99783 beta-lactamase_156_A183P,beta-lactamase_156_183,TEM-1,beta-lactamase_156,P62593,0.997836,NO,183,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.231,-3.812,2.581,,0.155,H,A,0.46,-0.91,23.859,23.859,77.62,HHH,-1.53367,0.111618,0.00296631,0.997836 beta-lactamase_2500_E272H,beta-lactamase_2500_272,TEM-1,beta-lactamase_2500,P62593,0.997837,NO,272,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.361275,0.00545371,0.997837 beta-lactamase_39_F64W,beta-lactamase_39_64,TEM-1,beta-lactamase_39,P62593,0.997841,NO,64,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-0.841,-4.422,3.581,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.0495842,0.000947691,0.997841 kka2_1:8_A150G,kka2_1:8_150,Kka2,kka2_1:8,P00552,0.997841,NO,150,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.949,-2.199,1.25,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.100394,0.0045009,0.997841 kka2_1:8_A150G,kka2_1:8_150,Kka2,kka2_1:8,P00552,0.997841,NO,150,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.949,-2.199,1.25,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.100394,0.0045009,0.997841 beta-lactamase_156_H24V,beta-lactamase_156_24,TEM-1,beta-lactamase_156,P62593,0.997842,NO,24,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-2.481,-3.524,1.043,,,,,,,2.708,,93.01,OBO,-2.0035,0.111618,0.00238894,0.997842 kka2_1:4_D156R,kka2_1:4_156,Kka2,kka2_1:4,P00552,0.997844,NO,156,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.696,-3.967,2.271,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.168804,0.00926998,0.997844 beta-lactamase_156_N173H,beta-lactamase_156_173,TEM-1,beta-lactamase_156,P62593,0.997856,NO,173,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-2.663,-4.635,1.972,,1.044,T,l,0.61,1.25,3.718,,77.62,OPA,-1.46633,0.111618,0.0033769,0.997856 beta-lactamase_156_K53S,beta-lactamase_156_53,TEM-1,beta-lactamase_156,P62593,0.997859,NO,53,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-2.313,-2.879,0.566,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.111618,0.00383383,0.997859 beta-lactamase_156_H287N,beta-lactamase_156_287,TEM-1,beta-lactamase_156,P62593,0.99786,NO,287,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,,,,,,,,,,,,,BBH,-1.111,0.111618,,0.99786 beta-lactamase_156_R41A,beta-lactamase_156_41,TEM-1,beta-lactamase_156,P62593,0.997862,NO,41,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-0.942,-3.041,2.099,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.111618,0.00123327,0.997862 beta-lactamase_39_I54N,beta-lactamase_39_54,TEM-1,beta-lactamase_39,P62593,0.997864,NO,54,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-2.838,-2.849,0.011,,0.669,E,B,0.48,-0.14,1.349,,73.78,BHH,-2.337,0.0495842,0.00403589,0.997864 beta-lactamase_2500_E87D,beta-lactamase_2500_87,TEM-1,beta-lactamase_2500,P62593,0.997865,NO,87,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.421,-2.265,0.844,,0.048,,B,1.04,0.92,17.923,17.923,64.69,PAP,-1.969,0.361275,0.00337888,0.997865 beta-lactamase_156_I229C,beta-lactamase_156_229,TEM-1,beta-lactamase_156,P62593,0.997866,NO,229,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.267,-4.722,3.455,,0.083,E,B,0.48,-0.76,1.114,,50,HHH,-1.58767,0.111618,0.00477249,0.997866 beta-lactamase_39_E169W,beta-lactamase_39_169,TEM-1,beta-lactamase_39,P62593,0.997869,NO,169,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.23,-5.379,4.149,,0.337,,A,1.04,1,15.633,15.633,73.08,PAH,-1.16533,0.0495842,0.00400994,0.997869 beta-lactamase_625_D83E,beta-lactamase_625_83,TEM-1,beta-lactamase_625,P62593,0.997869,NO,83,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.066,-2.025,0.959,,0.354,H,A,0.75,0.22,0.239,,48.95,HAH,-1.34733,0.213352,0.00205968,0.997869 beta-lactamase_39_A200R,beta-lactamase_39_200,TEM-1,beta-lactamase_39,P62593,0.99787,NO,200,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.878,-2.634,0.756,,0.757,H,A,0.46,-0.19,1.54,,77.62,HHP,-2.001,0.0495842,0.0060056,0.99787 beta-lactamase_625_L188C,beta-lactamase_625_188,TEM-1,beta-lactamase_625,P62593,0.997872,NO,188,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.166,-4.777,3.611,,,H,A,0.55,-0.3,2.982,,60.14,PHB,-1.47033,0.213352,0.00295687,0.997872 beta-lactamase_625_F149H,beta-lactamase_625_149,TEM-1,beta-lactamase_625,P62593,0.997873,NO,149,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.299,-4.304,3.005,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.213352,0.00418462,0.997873 beta-lactamase_2500_S256T,beta-lactamase_2500_256,TEM-1,beta-lactamase_2500,P62593,0.997874,NO,256,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.361275,0.00710634,0.997874 beta-lactamase_156_R159L,beta-lactamase_156_159,TEM-1,beta-lactamase_156,P62593,0.997878,NO,159,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-0.94,-3.407,2.467,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.111618,0.00108472,0.997878 beta-lactamase_625_M184Y,beta-lactamase_625_184,TEM-1,beta-lactamase_625,P62593,0.99788,NO,184,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.593,-4.027,2.434,,,H,A,0.55,-0.87,2.765,,62.94,HHH,-1.41,0.213352,0.00356019,0.99788 beta-lactamase_156_R202A,beta-lactamase_156_202,TEM-1,beta-lactamase_156,P62593,0.997882,NO,202,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.292,-2.462,1.17,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.111618,0.00321899,0.997882 beta-lactamase_625_K144F,beta-lactamase_625_144,TEM-1,beta-lactamase_625,P62593,0.997887,NO,144,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-2.388,-4.427,2.039,,0.863,H,A,2.34,1.27,2.313,,77.62,OBA,-1.904,0.213352,0.00481141,0.997887 beta-lactamase_625_G194S,beta-lactamase_625_194,TEM-1,beta-lactamase_625,P62593,0.997891,NO,194,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.396,-2.171,0.775,,0.276,S,b,0.29,0.36,3.593,,67.83,POA,-1.832,0.213352,0.00392163,0.997891 beta-lactamase_2500_R275A,beta-lactamase_2500_275,TEM-1,beta-lactamase_2500,P62593,0.997892,NO,275,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.361275,0.0141984,0.997892 gb1_T275P,gb1_275,gb1,gb1,P06654,0.997894,NO,275,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.727,-3.651,1.924,,,,,,,0.511,,35.71,HPB,-1.637,0.177985,0.00606618,0.997894 beta-lactamase_39_A268F,beta-lactamase_39_268,TEM-1,beta-lactamase_39,P62593,0.997901,NO,268,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.0495842,0.0102525,0.997901 beta-lactamase_625_E175P,beta-lactamase_625_175,TEM-1,beta-lactamase_625,P62593,0.997901,NO,175,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.336,-1.972,-0.364,,0.551,,A,1.04,1.05,8.527,8.527,77.62,AAB,-1.31233,0.213352,0.00482205,0.997901 beta-lactamase_S57E,beta-lactamase_57,TEM-1,beta-lactamase,P62593,0.997901,NO,57,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.918,-2.903,0.985,5.64201,0.352,E,B,0.25,-0.18,1.971,,72.73,APH,-2.29167,0.221079,0.00492804,0.997901 beta-lactamase_156_Q88T,beta-lactamase_156_88,TEM-1,beta-lactamase_156,P62593,0.997905,NO,88,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.086,-2.693,0.607,,0.807,,B,0.64,2.03,0.911,,77.62,APH,-1.53433,0.111618,0.00504167,0.997905 beta-lactamase_2500_P217K,beta-lactamase_2500_217,TEM-1,beta-lactamase_2500,P62593,0.997906,NO,217,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-2.062,-2.687,0.625,,0.496,I,A,0.52,-0.33,0.431,,74.48,OOH,-1.64333,0.361275,0.00463211,0.997906 beta-lactamase_156_R242H,beta-lactamase_156_242,TEM-1,beta-lactamase_156,P62593,0.997907,NO,242,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.111618,0.00452879,0.997907 beta-lactamase_156_D155N,beta-lactamase_156_155,TEM-1,beta-lactamase_156,P62593,0.997908,NO,155,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.889,-2.502,1.613,,0.049,,B,0.75,-0.9,0.315,,64.69,OAB,-1.62267,0.111618,0.00135315,0.997908 beta-lactamase_625_V101M,beta-lactamase_625_101,TEM-1,beta-lactamase_625,P62593,0.997908,NO,101,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.295,-2.812,1.517,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.213352,0.00374492,0.997908 beta-lactamase_2500_A247I,beta-lactamase_2500_247,TEM-1,beta-lactamase_2500,P62593,0.99791,NO,247,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.361275,0.00611275,0.99791 kka2_1:1_I2I,kka2_1:1_2,Kka2,kka2_1:1,P00552,0.99791,NO,2,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.787,-1.787,,,,,,,,2.329,,71.59,HHA,-1.92433,0.520039,0.00246644,0.99791 kka2_1:2_D52D,kka2_1:2_52,Kka2,kka2_1:2,P00552,0.997917,NO,52,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.271,-2.271,,,0.22,E,B,0.75,0.8,1.123,,71.59,PAH,-2.38367,0.295029,0.00175694,0.997917 beta-lactamase_625_H151K,beta-lactamase_625_151,TEM-1,beta-lactamase_625,P62593,0.99792,NO,151,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-2.96,-3.032,0.072,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.213352,0.00216946,0.99792 beta-lactamase_625_A77C,beta-lactamase_625_77,TEM-1,beta-lactamase_625,P62593,0.997925,NO,77,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.234,-4.708,3.474,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.213352,0.00282362,0.997925 beta-lactamase_L150I,beta-lactamase_150,TEM-1,beta-lactamase,P62593,0.997925,NO,150,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.326,-3.18,1.854,5.15566,,H,A,1.75,-0.2,1.615,,62.94,HHB,-1.86167,0.221079,0.00463171,0.997925 beta-lactamase_625_T269R,beta-lactamase_625_269,TEM-1,beta-lactamase_625,P62593,0.997926,NO,269,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.213352,0.00950944,0.997926 kka2_1:2_L53L,kka2_1:2_53,Kka2,kka2_1:2,P00552,0.99793,NO,53,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-2.681,-2.681,,,0.569,E,B,0.55,0.8,19.536,19.536,71.59,AHP,-2.47433,0.295029,0.00671168,0.99793 Pab1_D144Q,Pab1_144,Pab1,Pab1,P04147,0.997932,NO,144,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.189,-3.397,2.208,,0.616,H,A,,0.6,,,,HAP,-1.40567,0.175299,0.00121131,0.997932 beta-lactamase_156_K286G,beta-lactamase_156_286,TEM-1,beta-lactamase_156,P62593,0.997933,NO,286,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.111618,,0.997933 beta-lactamase_39_R257S,beta-lactamase_39_257,TEM-1,beta-lactamase_39,P62593,0.997934,NO,257,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.0495842,0.00756629,0.997934 beta-lactamase_625_M180E,beta-lactamase_625_180,TEM-1,beta-lactamase_625,P62593,0.997943,NO,180,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-2.795,-3.532,0.737,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.213352,0.00552048,0.997943 beta-lactamase_625_P165V,beta-lactamase_625_165,TEM-1,beta-lactamase_625,P62593,0.997944,NO,165,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.373,-3.333,1.96,,0.203,T,A,0.52,-0.31,0.414,,73.78,AOA,-1.359,0.213352,0.00549538,0.997944 beta-lactamase_156_A200S,beta-lactamase_156_200,TEM-1,beta-lactamase_156,P62593,0.997946,NO,200,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.878,-2.183,0.305,,0.757,H,A,0.46,-0.19,16.368,16.368,77.62,HHP,-2.001,0.111618,0.0060056,0.997946 beta-lactamase_156_I54K,beta-lactamase_156_54,TEM-1,beta-lactamase_156,P62593,0.997947,NO,54,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-2.838,-2.926,0.088,,0.669,E,B,0.48,-0.14,0.541,,73.78,BHH,-2.337,0.111618,0.00403589,0.997947 beta-lactamase_K53R,beta-lactamase_53,TEM-1,beta-lactamase,P62593,0.997949,NO,53,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-2.313,-2.027,-0.286,5.93654,0.589,,B,1.82,1.15,19.72,19.72,77.62,OBH,-2.1,0.221079,0.00383383,0.997949 beta-lactamase_625_S241H,beta-lactamase_625_241,TEM-1,beta-lactamase_625,P62593,0.99795,NO,241,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.213352,0.00452736,0.99795 beta-lactamase_156_A278R,beta-lactamase_156_278,TEM-1,beta-lactamase_156,P62593,0.997955,NO,278,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.111618,0.0310297,0.997955 beta-lactamase_Q4R,beta-lactamase_4,TEM-1,beta-lactamase,P62593,0.997957,NO,4,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,,-1.861,-0.703,,,,,,,,,,HPB,,0.221079,0.00316562,0.997957 kka2_1:8_R173R,kka2_1:8_173,Kka2,kka2_1:8,P00552,0.997957,NO,173,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.407,-2.407,,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.100394,0.00784999,0.997957 kka2_1:8_R173R,kka2_1:8_173,Kka2,kka2_1:8,P00552,0.997957,NO,173,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.407,-2.407,,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.100394,0.00784999,0.997957 beta-lactamase_625_N173T,beta-lactamase_625_173,TEM-1,beta-lactamase_625,P62593,0.997967,NO,173,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-2.663,-3.589,0.926,,1.044,T,l,0.61,1.25,1.426,,77.62,OPA,-1.46633,0.213352,0.0033769,0.997967 beta-lactamase_625_W163F,beta-lactamase_625_163,TEM-1,beta-lactamase_625,P62593,0.997967,NO,163,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-1.843,-3.138,1.295,,0.467,,B,0.47,-0.5,5.019,,63.99,BHA,-1.269,0.213352,0.00418955,0.997967 beta-lactamase_156_L205V,beta-lactamase_156_205,TEM-1,beta-lactamase_156,P62593,0.997969,NO,205,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.922,-2.938,2.016,,,H,A,0.55,-0.46,0.678,,42.31,PHH,-1.57767,0.111618,0.00255802,0.997969 beta-lactamase_39_Q97G,beta-lactamase_39_97,TEM-1,beta-lactamase_39,P62593,0.99797,NO,97,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.072,-2.827,0.755,,0.823,G,A,0.64,2.42,4.457,,77.62,PPP,-2.43833,0.0495842,0.0045116,0.99797 beta-lactamase_39_C121L,beta-lactamase_39_121,TEM-1,beta-lactamase_39,P62593,0.997971,NO,121,C,L,CL,Special,Hydrophobic,5.07,9.7088,4.6388,198,121,131,10,108.5,166.7,58.2,-0.953,-3.182,2.229,,,H,A,0.46,-0.81,7.644,,63.29,HOP,-1.46767,0.0495842,0.000744322,0.997971 beta-lactamase_156_K53V,beta-lactamase_156_53,TEM-1,beta-lactamase_156,P62593,0.997972,NO,53,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-2.313,-3.678,1.365,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.111618,0.00383383,0.997972 beta-lactamase_2500_R118F,beta-lactamase_2500_118,TEM-1,beta-lactamase_2500,P62593,0.997972,NO,118,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.413,-4.338,1.925,,0.457,H,A,1.2,1.39,2.144,,77.62,HBA,-1.785,0.361275,0.00538794,0.997972 Pab1_P200T,Pab1_200,Pab1,Pab1,P04147,0.997978,NO,200,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.871,-3.446,1.575,,,,,,,3.877,,80.59,HOO,-1.7005,0.175299,0.00190795,0.997978 beta-lactamase_39_P224F,beta-lactamase_39_224,TEM-1,beta-lactamase_39,P62593,0.997979,NO,224,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.893,-4.486,3.593,,0.383,,B,0.52,-0.3,3.169,,74.48,HOH,-1.26433,0.0495842,0.00189564,0.997979 kka2_1:4_V16V,kka2_1:4_16,Kka2,kka2_1:4,P00552,0.997982,NO,16,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-3.087,-3.087,,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.168804,0.00694011,0.997982 beta-lactamase_156_D113E,beta-lactamase_156_113,TEM-1,beta-lactamase_156,P62593,0.997983,NO,113,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.829,-2.32,0.491,,0.665,T,A,0.75,0.91,2.973,,73.08,PAO,-1.703,0.111618,0.00474112,0.997983 beta-lactamase_156_Y262M,beta-lactamase_156_262,TEM-1,beta-lactamase_156,P62593,0.997983,NO,262,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.111618,0.00853516,0.997983 beta-lactamase_625_L28W,beta-lactamase_625_28,TEM-1,beta-lactamase_625,P62593,0.997984,NO,28,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.579,-5.332,3.753,,0.277,H,A,0.55,-0.16,2.716,,93.01,PHH,-2.11333,0.213352,0.00359321,0.997984 Pab1_E175A,Pab1_175,Pab1,Pab1,P04147,0.997984,NO,175,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.055,-3.051,0.996,,,,,,,,,,AAA,-1.82667,0.175299,0.00203137,0.997984 kka2_1:2_A13A,kka2_1:2_13,Kka2,kka2_1:2,P00552,0.997987,NO,13,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.248,-2.248,,,0.689,G,A,0.46,0.99,,,92.05,OHH,-1.646,0.295029,0.00784241,0.997987 PSD95pdz3_G351M,PSD95pdz3_351,PSD95pdz3,PSD95pdz3,P31016,0.997989,NO,351,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.008,-4.612,3.604,5.44798,,,,,20.7625,,,,POA,-1.37133,0.0758425,0.000691282,0.997989 kka2_1:2_L7L,kka2_1:2_7,Kka2,kka2_1:2,P00552,0.997996,NO,7,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.926,-1.926,,,,,,,,3.012,,71.59,OHB,-2.12333,0.295029,0.00269456,0.997996 beta-lactamase_39_T263H,beta-lactamase_39_263,TEM-1,beta-lactamase_39,P62593,0.998005,NO,263,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.0495842,0.0110582,0.998005 beta-lactamase_625_K32V,beta-lactamase_625_32,TEM-1,beta-lactamase_625,P62593,0.998005,NO,32,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.984,-3.477,1.493,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.213352,0.00401283,0.998005 beta-lactamase_39_L191M,beta-lactamase_39_191,TEM-1,beta-lactamase_39,P62593,0.998011,NO,191,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.087,-4.016,2.929,,,H,A,0.55,0.09,1.372,,63.29,BHH,-1.445,0.0495842,0.00263549,0.998011 beta-lactamase_625_E145M,beta-lactamase_625_145,TEM-1,beta-lactamase_625,P62593,0.998014,NO,145,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.357,-4.807,2.45,,0.545,H,A,1.04,0.79,2.64,,77.62,BAH,-2.069,0.213352,0.00553285,0.998014 beta-lactamase_156_N168D,beta-lactamase_156_168,TEM-1,beta-lactamase_156,P62593,0.998016,NO,168,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-1.029,-3.143,2.114,,0.113,G,A,0.61,-0.4,1.014,,44.41,HPA,-1.13233,0.111618,0.00288667,0.998016 beta-lactamase_625_A77V,beta-lactamase_625_77,TEM-1,beta-lactamase_625,P62593,0.998018,NO,77,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.234,-2.654,1.42,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.213352,0.00282362,0.998018 kka2_1:1_V80V,kka2_1:1_80,Kka2,kka2_1:1,P00552,0.998019,NO,80,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.144,-1.144,,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.520039,0.00488211,0.998019 kka2_1:1_Q4Q,kka2_1:1_4,Kka2,kka2_1:1,P00552,0.998024,NO,4,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.361,-2.361,,,,,,,,5.615,,71.59,APA,-1.95533,0.520039,0.00239179,0.998024 beta-lactamase_156_G154R,beta-lactamase_156_154,TEM-1,beta-lactamase_156,P62593,0.998025,NO,154,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.823,-3.969,3.146,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.111618,0.00180205,0.998025 beta-lactamase_156_P165L,beta-lactamase_156_165,TEM-1,beta-lactamase_156,P62593,0.998027,NO,165,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.373,-3.388,2.015,,0.203,T,A,0.52,-0.31,3.907,,73.78,AOA,-1.359,0.111618,0.00549538,0.998027 PSD95pdz3_Y392S,PSD95pdz3_392,PSD95pdz3,PSD95pdz3,P31016,0.998027,NO,392,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-1.437,-3.292,1.855,5.20337,,,,,11.725,,,,PHB,-1.51733,0.0758425,0.000935211,0.998027 beta-lactamase_0_L219K,beta-lactamase_0_219,TEM-1,beta-lactamase_0,P62593,0.998028,NO,219,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.313,-3.875,2.562,,,I,A,0.55,-0.51,6.513,6.513,74.48,HHB,-1.21533,0.0500837,0.00664345,0.998028 beta-lactamase_156_T187H,beta-lactamase_156_187,TEM-1,beta-lactamase_156,P62593,0.998032,NO,187,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.401,-4.688,3.287,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.111618,0.00491782,0.998032 beta-lactamase_156_T126H,beta-lactamase_156_126,TEM-1,beta-lactamase_156,P62593,0.998035,NO,126,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.122,-4.699,3.577,,0.05,H,A,0.22,-0.05,1.14,,44.41,HPH,-1.60467,0.111618,0.00244552,0.998035 beta-lactamase_625_L55Y,beta-lactamase_625_55,TEM-1,beta-lactamase_625,P62593,0.998036,NO,55,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.86,-3.812,1.952,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.213352,0.00403741,0.998036 beta-lactamase_156_D33H,beta-lactamase_156_33,TEM-1,beta-lactamase_156,P62593,0.99804,NO,33,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.321,-4.654,2.333,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.111618,0.00435556,0.99804 beta-lactamase_K53H,beta-lactamase_53,TEM-1,beta-lactamase,P62593,0.998041,NO,53,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-2.313,-4.67,2.357,5.93654,0.589,,B,1.82,1.15,19.72,19.72,77.62,OBH,-2.1,0.221079,0.00383383,0.998041 PSD95pdz3_S350K,PSD95pdz3_350,PSD95pdz3,PSD95pdz3,P31016,0.998043,NO,350,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.519,-2.914,1.395,4.97629,,,,,25.01,,,,HPO,-1.29133,0.0758425,0.000704883,0.998043 beta-lactamase_156_W163P,beta-lactamase_156_163,TEM-1,beta-lactamase_156,P62593,0.998047,NO,163,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-1.843,-4.201,2.358,,0.467,,B,0.47,-0.5,15.095,15.095,63.99,BHA,-1.269,0.111618,0.00418955,0.998047 beta-lactamase_156_G52Q,beta-lactamase_156_52,TEM-1,beta-lactamase_156,P62593,0.998049,NO,52,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.149,-2.995,1.846,,0.299,,l,0.29,-0.04,1.179,,64.69,POB,-1.66267,0.111618,0.00340138,0.998049 beta-lactamase_156_S57R,beta-lactamase_156_57,TEM-1,beta-lactamase_156,P62593,0.998049,NO,57,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.918,-3.069,1.151,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.111618,0.00492804,0.998049 beta-lactamase_156_L100Q,beta-lactamase_156_100,TEM-1,beta-lactamase_156,P62593,0.998052,NO,100,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.218,-4.259,3.041,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.111618,0.00413885,0.998052 beta-lactamase_156_T264D,beta-lactamase_156_264,TEM-1,beta-lactamase_156,P62593,0.998053,NO,264,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.111618,0.0119399,0.998053 beta-lactamase_2500_E46S,beta-lactamase_2500_46,TEM-1,beta-lactamase_2500,P62593,0.99806,NO,46,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.94,-3.545,1.605,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.361275,0.00427568,0.99806 beta-lactamase_2500_G194E,beta-lactamase_2500_194,TEM-1,beta-lactamase_2500,P62593,0.998063,NO,194,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.396,-2.361,0.965,,0.276,S,b,0.29,0.36,3.593,,67.83,POA,-1.832,0.361275,0.00392163,0.998063 beta-lactamase_39_L167I,beta-lactamase_39_167,TEM-1,beta-lactamase_39,P62593,0.998063,NO,167,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.138,-3.085,1.947,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.0495842,0.00303566,0.998063 beta-lactamase_39_E238L,beta-lactamase_39_238,TEM-1,beta-lactamase_39,P62593,0.998064,NO,238,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.0495842,0.00743256,0.998064 beta-lactamase_156_V157D,beta-lactamase_156_157,TEM-1,beta-lactamase_156,P62593,0.998069,NO,157,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.751,-3.908,2.157,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.111618,0.00506849,0.998069 beta-lactamase_39_E169M,beta-lactamase_39_169,TEM-1,beta-lactamase_39,P62593,0.998072,NO,169,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.23,-4.676,3.446,,0.337,,A,1.04,1,15.633,15.633,73.08,PAH,-1.16533,0.0495842,0.00400994,0.998072 kka2_1:8_A172A,kka2_1:8_172,Kka2,kka2_1:8,P00552,0.998072,NO,172,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.757,-1.757,,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.100394,0.0079265,0.998072 kka2_1:8_A172A,kka2_1:8_172,Kka2,kka2_1:8,P00552,0.998072,NO,172,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.757,-1.757,,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.100394,0.0079265,0.998072 beta-lactamase_39_A123G,beta-lactamase_39_123,TEM-1,beta-lactamase_39,P62593,0.998075,NO,123,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.834,-2.991,2.157,,0.039,H,A,0.46,-0.72,0.705,,41.26,PHH,-1.47367,0.0495842,0.0010157,0.998075 kka2_1:4_I2I,kka2_1:4_2,Kka2,kka2_1:4,P00552,0.998076,NO,2,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.787,-1.787,,,,,,,,,,71.59,HHA,-1.92433,0.168804,0.00246644,0.998076 beta-lactamase_625_V214H,beta-lactamase_625_214,TEM-1,beta-lactamase_625,P62593,0.998078,NO,214,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.299,-4.922,3.623,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.213352,0.00628442,0.998078 beta-lactamase_156_E35C,beta-lactamase_156_35,TEM-1,beta-lactamase_156,P62593,0.99808,NO,35,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-0.869,-5.31,4.441,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.111618,0.00174441,0.99808 beta-lactamase_156_S201R,beta-lactamase_156_201,TEM-1,beta-lactamase_156,P62593,0.998081,NO,201,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.183,-3.779,2.596,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.111618,0.00198815,0.998081 beta-lactamase_625_E238S,beta-lactamase_625_238,TEM-1,beta-lactamase_625,P62593,0.998084,NO,238,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.213352,0.00743256,0.998084 beta-lactamase_156_G194N,beta-lactamase_156_194,TEM-1,beta-lactamase_156,P62593,0.998085,NO,194,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.396,-2.573,1.177,,0.276,S,b,0.29,0.36,1.346,,67.83,POA,-1.832,0.111618,0.00392163,0.998085 beta-lactamase_2500_E26N,beta-lactamase_2500_26,TEM-1,beta-lactamase_2500,P62593,0.998086,NO,26,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.454,-3.711,1.257,,0.54,H,A,1.04,0.98,0.49,,93.01,OAP,-1.96167,0.361275,0.00297948,0.998086 beta-lactamase_156_D207L,beta-lactamase_156_207,TEM-1,beta-lactamase_156,P62593,0.998087,NO,207,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.064,-3.704,1.64,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.111618,0.00592942,0.998087 beta-lactamase_156_L49P,beta-lactamase_156_49,TEM-1,beta-lactamase_156,P62593,0.998089,NO,49,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.897,-2.49,0.593,,0.131,T,A,0.55,0.04,3.112,,64.69,AHP,-1.99233,0.111618,0.00401477,0.998089 beta-lactamase_39_A247G,beta-lactamase_39_247,TEM-1,beta-lactamase_39,P62593,0.998091,NO,247,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.0495842,0.00611275,0.998091 beta-lactamase_625_L28M,beta-lactamase_625_28,TEM-1,beta-lactamase_625,P62593,0.998093,NO,28,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.579,-4.156,2.577,,0.277,H,A,0.55,-0.16,2.716,,93.01,PHH,-2.11333,0.213352,0.00359321,0.998093 beta-lactamase_P172E,beta-lactamase_172,TEM-1,beta-lactamase,P62593,0.998093,NO,172,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.998,-3.52,2.522,5.98941,0.639,T,b,1.1,0.24,2.087,,74.48,HOP,-2.03067,0.221079,0.00312594,0.998093 beta-lactamase_2500_K109G,beta-lactamase_2500_109,TEM-1,beta-lactamase_2500,P62593,0.998096,NO,109,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.734,-2.852,1.118,,0.787,G,A,2.34,2.21,0.998,,72.73,ABB,-1.63333,0.361275,0.00462493,0.998096 beta-lactamase_39_A77V,beta-lactamase_39_77,TEM-1,beta-lactamase_39,P62593,0.998097,NO,77,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.234,-2.654,1.42,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.0495842,0.00282362,0.998097 beta-lactamase_2500_G76A,beta-lactamase_2500_76,TEM-1,beta-lactamase_2500,P62593,0.998099,NO,76,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.189,-1.531,0.342,,,H,A,0.29,-0.67,1.012,,67.83,OOH,-1.22267,0.361275,0.00476637,0.998099 kka2_1:1_D238D,kka2_1:1_238,Kka2,kka2_1:1,P00552,0.998101,NO,238,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.83,-2.83,,,0.604,H,A,0.75,-0.33,11.329,11.329,92.05,HAB,-2.633,0.520039,0.0113863,0.998101 kka2_1:4_A248A,kka2_1:4_248,Kka2,kka2_1:4,P00552,0.998101,NO,248,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.124,-2.124,,,0.825,S,b,0.46,0.46,,,92.05,HHO,-2.15,0.168804,0.0125484,0.998101 beta-lactamase_156_S266A,beta-lactamase_156_266,TEM-1,beta-lactamase_156,P62593,0.998105,NO,266,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.369,-2.686,1.317,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.111618,0.0140785,0.998105 beta-lactamase_625_I261L,beta-lactamase_625_261,TEM-1,beta-lactamase_625,P62593,0.998106,NO,261,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.213352,0.0123091,0.998106 beta-lactamase_156_G85A,beta-lactamase_156_85,TEM-1,beta-lactamase_156,P62593,0.99811,NO,85,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.011,-3.043,2.032,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.111618,0.00252173,0.99811 beta-lactamase_156_R202G,beta-lactamase_156_202,TEM-1,beta-lactamase_156,P62593,0.998113,NO,202,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.292,-3.349,2.057,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.111618,0.00321899,0.998113 beta-lactamase_E61N,beta-lactamase_61,TEM-1,beta-lactamase,P62593,0.998115,NO,61,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.115,-2.373,0.258,6.29701,0.775,T,a,0.52,1.29,1.975,,77.62,OAA,-1.92567,0.221079,0.00440955,0.998115 beta-lactamase_625_E279G,beta-lactamase_625_279,TEM-1,beta-lactamase_625,P62593,0.998116,NO,279,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.038,-3.588,2.55,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.213352,0.0192826,0.998116 kka2_1:2_E59Q,kka2_1:2_59,Kka2,kka2_1:2,P00552,0.998118,NO,59,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-0.952,-2.672,1.72,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.295029,0.00280355,0.998118 kka2_1:1_V242V,kka2_1:1_242,Kka2,kka2_1:1,P00552,0.998119,NO,242,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-2.687,-2.687,,,0.75,H,A,0.44,-0.37,4.987,,71.59,HHH,-2.16533,0.520039,0.0102575,0.998119 beta-lactamase_156_G265P,beta-lactamase_156_265,TEM-1,beta-lactamase_156,P62593,0.998121,NO,265,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.111618,0.00811926,0.998121 beta-lactamase_156_N50F,beta-lactamase_156_50,TEM-1,beta-lactamase_156,P62593,0.998123,NO,50,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-2.979,-4.333,1.354,,0.912,T,A,0.61,1.24,13.295,13.295,77.62,HPP,-2.134,0.111618,0.0047211,0.998123 beta-lactamase_625_R159H,beta-lactamase_625_159,TEM-1,beta-lactamase_625,P62593,0.998124,NO,159,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-0.94,-2.789,1.849,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.213352,0.00108472,0.998124 beta-lactamase_156_D33E,beta-lactamase_156_33,TEM-1,beta-lactamase_156,P62593,0.99813,NO,33,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.321,-2.159,-0.162,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.111618,0.00435556,0.99813 beta-lactamase_156_L111Y,beta-lactamase_156_111,TEM-1,beta-lactamase_156,P62593,0.99813,NO,111,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.76,-4.039,2.279,,0.328,T,A,0.55,0.93,2.26,,64.34,BHP,-1.884,0.111618,0.00480671,0.99813 kka2_1:4_E96E,kka2_1:4_96,Kka2,kka2_1:4,P00552,0.998133,NO,96,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.573,-2.573,,,0.476,,B,1.52,-0.65,1.254,,71.59,OAH,-2.143,0.168804,0.00369441,0.998133 beta-lactamase_625_H94K,beta-lactamase_625_94,TEM-1,beta-lactamase_625,P62593,0.998134,NO,94,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-2.5,-2.567,0.067,,0.776,,B,0.17,1.24,19.42,19.42,77.62,HBH,-1.872,0.213352,0.00389226,0.998134 beta-lactamase_156_Y44L,beta-lactamase_156_44,TEM-1,beta-lactamase_156,P62593,0.998136,NO,44,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-2.547,-2.196,-0.351,,,E,B,0.21,-0.45,2.184,,73.78,OHH,-1.86267,0.111618,0.00426364,0.998136 kka2_1:2_G43G,kka2_1:2_43,Kka2,kka2_1:2,P00552,0.998136,NO,43,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.587,-1.587,,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.295029,0.0071925,0.998136 beta-lactamase_39_A84Y,beta-lactamase_39_84,TEM-1,beta-lactamase_39,P62593,0.998139,NO,84,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.651,-4.29,2.639,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.0495842,0.00503822,0.998139 beta-lactamase_625_N152Y,beta-lactamase_625_152,TEM-1,beta-lactamase_625,P62593,0.998141,NO,152,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-2.757,-4.312,1.555,,0.863,H,A,0.61,0.92,2.061,,77.62,BPH,-2.97,0.213352,0.00471429,0.998141 beta-lactamase_156_R202H,beta-lactamase_156_202,TEM-1,beta-lactamase_156,P62593,0.998142,NO,202,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.292,-4.365,3.073,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.111618,0.00321899,0.998142 beta-lactamase_2500_I171N,beta-lactamase_2500_171,TEM-1,beta-lactamase_2500,P62593,0.998142,NO,171,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-2.431,-3.904,1.473,,0.361,,B,0.48,0.53,1.66,,77.62,HHO,-1.55533,0.361275,0.00623355,0.998142 beta-lactamase_625_R118D,beta-lactamase_625_118,TEM-1,beta-lactamase_625,P62593,0.998144,NO,118,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.413,-2.866,0.453,,0.457,H,A,1.2,1.39,2.144,,77.62,HBA,-1.785,0.213352,0.00538794,0.998144 kka2_1:4_R202S,kka2_1:4_202,Kka2,kka2_1:4,P00552,0.998146,NO,202,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.761,-2.977,1.216,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.168804,0.00696498,0.998146 beta-lactamase_2500_K254E,beta-lactamase_2500_254,TEM-1,beta-lactamase_2500,P62593,0.998149,NO,254,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.361275,0.00369,0.998149 kka2_1:1_F20F,kka2_1:1_20,Kka2,kka2_1:1,P00552,0.998153,NO,20,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-3.354,-3.354,,,0.935,T,B,0.58,-0.41,1.657,,92.05,HHO,-1.992,0.520039,0.00701744,0.998153 beta-lactamase_156_P172V,beta-lactamase_156_172,TEM-1,beta-lactamase_156,P62593,0.998154,NO,172,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.998,-3.483,2.485,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.111618,0.00312594,0.998154 beta-lactamase_156_V82N,beta-lactamase_156_82,TEM-1,beta-lactamase_156,P62593,0.998158,NO,82,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.325,-2.935,1.61,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.111618,0.00397046,0.998158 beta-lactamase_625_H110N,beta-lactamase_625_110,TEM-1,beta-lactamase_625,P62593,0.998158,NO,110,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-1.706,-3.626,1.92,,0.341,G,a,0.17,1.08,31.31,31.31,64.69,BBH,-1.73333,0.213352,0.00441499,0.998158 kka2_1:2_V46V,kka2_1:2_46,Kka2,kka2_1:2,P00552,0.998158,NO,46,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-2.62,-2.62,,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.295029,0.00631301,0.998158 beta-lactamase_39_P65S,beta-lactamase_39_65,TEM-1,beta-lactamase_39,P62593,0.99816,NO,65,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.894,-3.44,2.546,,0.098,E,B,0.52,-0.62,0.623,,40.56,HOH,-1.03233,0.0495842,0.00152776,0.99816 kka2_1:1_Q155Q,kka2_1:1_155,Kka2,kka2_1:1,P00552,0.99816,NO,155,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.606,-2.606,,,0.525,T,A,0.4,1.49,4.415,,63.64,APA,-1.726,0.520039,0.00641853,0.99816 beta-lactamase_156_R162C,beta-lactamase_156_162,TEM-1,beta-lactamase_156,P62593,0.998161,NO,162,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.016,-5.08,4.064,,0.124,S,B,1.2,-0.37,7.444,,64.69,ABH,-1.25,0.111618,0.000561334,0.998161 kka2_1:4_E3E,kka2_1:4_3,Kka2,kka2_1:4,P00552,0.998162,NO,3,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.199,-2.199,,,,,,,,7.22,,92.05,HAP,-2.11567,0.168804,0.00267607,0.998162 beta-lactamase_625_S221Y,beta-lactamase_625_221,TEM-1,beta-lactamase_625,P62593,0.998164,NO,221,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.754,-4.278,2.524,,0.624,H,A,0.27,-0.2,1.495,,74.48,BPH,-1.59967,0.213352,0.0046094,0.998164 beta-lactamase_625_E61G,beta-lactamase_625_61,TEM-1,beta-lactamase_625,P62593,0.998165,NO,61,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.115,-2.393,0.278,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.213352,0.00440955,0.998165 kka2_1:2_T146T,kka2_1:2_146,Kka2,kka2_1:2,P00552,0.998167,NO,146,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.978,-2.978,,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.295029,0.00606474,0.998167 beta-lactamase_A182C,beta-lactamase_182,TEM-1,beta-lactamase,P62593,0.998172,NO,182,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.777,-5.025,3.248,4.98609,0.136,H,A,0.52,-0.66,2.032,,93.01,OHH,-1.27367,0.221079,0.00559099,0.998172 beta-lactamase_39_M184V,beta-lactamase_39_184,TEM-1,beta-lactamase_39,P62593,0.998174,NO,184,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.593,-2.346,0.753,,,H,A,0.55,-0.87,2.893,,62.94,HHH,-1.41,0.0495842,0.00356019,0.998174 kka2_1:2_H8H,kka2_1:2_8,Kka2,kka2_1:2,P00552,0.998174,NO,8,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-2.759,-2.759,,,,,,,,,,71.59,HBH,-2.25467,0.295029,0.00256422,0.998174 kka2_1:1_V46V,kka2_1:1_46,Kka2,kka2_1:1,P00552,0.998176,NO,46,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-2.62,-2.62,,,0.192,.,B,0.44,-1.12,20.149,20.149,92.05,OHH,-1.88633,0.520039,0.00631301,0.998176 kka2_1:4_D5D,kka2_1:4_5,Kka2,kka2_1:4,P00552,0.998177,NO,5,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.306,-1.306,,,,,,,,,,71.59,PAO,-1.784,0.168804,0.00222864,0.998177 beta-lactamase_39_A124M,beta-lactamase_39_124,TEM-1,beta-lactamase_39,P62593,0.998181,NO,124,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.181,-4.519,3.338,,,H,A,0.46,-0.9,1.367,,64.34,HHH,-1.152,0.0495842,0.00481399,0.998181 beta-lactamase_156_Q37W,beta-lactamase_156_37,TEM-1,beta-lactamase_156,P62593,0.998182,NO,37,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.134,-3.439,1.305,,0.613,H,A,0.64,1.98,12.052,12.052,73.08,APH,-2.06967,0.111618,0.00425833,0.998182 beta-lactamase_625_L55K,beta-lactamase_625_55,TEM-1,beta-lactamase_625,P62593,0.998187,NO,55,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.86,-3.791,1.931,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.213352,0.00403741,0.998187 beta-lactamase_F13L,beta-lactamase_13,TEM-1,beta-lactamase,P62593,0.998188,NO,13,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-2.394,-1.491,-0.903,,,,,,,4.079,,77.62,OHH,-2.382,0.221079,0.0029078,0.998188 beta-lactamase_2500_K30R,beta-lactamase_2500_30,TEM-1,beta-lactamase_2500,P62593,0.998198,NO,30,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-2.307,-2.265,-0.042,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.361275,0.00448593,0.998198 kka2_1:4_D238D,kka2_1:4_238,Kka2,kka2_1:4,P00552,0.998198,NO,238,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.83,-2.83,,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.168804,0.0113863,0.998198 beta-lactamase_39_G114I,beta-lactamase_39_114,TEM-1,beta-lactamase_39,P62593,0.998203,NO,114,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.094,-4.083,2.989,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.0495842,0.00224919,0.998203 beta-lactamase_39_Q267S,beta-lactamase_39_267,TEM-1,beta-lactamase_39,P62593,0.998204,NO,267,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.0495842,0.0102128,0.998204 beta-lactamase_39_E102R,beta-lactamase_39_102,TEM-1,beta-lactamase_39,P62593,0.99821,NO,102,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.118,-3.801,1.683,,0.722,S,B,1.04,1.82,3.87,,73.08,HAH,-1.581,0.0495842,0.00486633,0.99821 beta-lactamase_156_A183V,beta-lactamase_156_183,TEM-1,beta-lactamase_156,P62593,0.998214,NO,183,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.231,-3.28,2.049,,0.155,H,A,0.46,-0.91,23.859,23.859,77.62,HHH,-1.53367,0.111618,0.00296631,0.998214 gb1_V247A,gb1_247,gb1,gb1,P06654,0.99822,NO,247,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.711,-2.77,1.059,,,,,,,0.805,,44.87,HHA,-1.485,0.177985,0.00435373,0.99822 kka2_1:2_E199E,kka2_1:2_199,Kka2,kka2_1:2,P00552,0.998221,NO,199,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.234,-2.234,,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.295029,0.00854122,0.998221 kka2_1:8_L70M,kka2_1:8_70,Kka2,kka2_1:8,P00552,0.998221,NO,70,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.017,-2.172,1.155,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.100394,0.00411884,0.998221 kka2_1:8_L70M,kka2_1:8_70,Kka2,kka2_1:8,P00552,0.998221,NO,70,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.017,-2.172,1.155,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.100394,0.00411884,0.998221 beta-lactamase_2500_A182S,beta-lactamase_2500_182,TEM-1,beta-lactamase_2500,P62593,0.998224,NO,182,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.777,-2.825,1.048,,0.136,H,A,0.46,-0.66,2.032,,93.01,OHH,-1.27367,0.361275,0.00559099,0.998224 kka2_1:1_C209V,kka2_1:1_209,Kka2,kka2_1:1,P00552,0.998225,NO,209,C,V,CV,Special,Hydrophobic,5.07,5.60847,0.538465,192,121,117,-4,108.5,140,31.5,-0.906,-3.299,2.393,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.520039,0.00260862,0.998225 kka2_1:8_A56W,kka2_1:8_56,Kka2,kka2_1:8,P00552,0.998232,NO,56,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.083,-5.608,3.525,,0.796,T,A,0.46,1.39,10.511,,71.59,OHH,-1.86867,0.100394,0.00717715,0.998232 kka2_1:8_A56W,kka2_1:8_56,Kka2,kka2_1:8,P00552,0.998232,NO,56,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.083,-5.608,3.525,,0.796,T,A,0.46,1.39,10.511,,71.59,OHH,-1.86867,0.100394,0.00717715,0.998232 beta-lactamase_39_L55S,beta-lactamase_39_55,TEM-1,beta-lactamase_39,P62593,0.998236,NO,55,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.86,-3.706,1.846,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.0495842,0.00403741,0.998236 beta-lactamase_39_S122N,beta-lactamase_39_122,TEM-1,beta-lactamase_39,P62593,0.998236,NO,122,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.406,-3.042,0.636,,0.352,H,A,0.27,-0.54,2.004,,77.62,OPH,-1.39767,0.0495842,0.00497825,0.998236 beta-lactamase_625_A282G,beta-lactamase_625_282,TEM-1,beta-lactamase_625,P62593,0.998236,NO,282,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.213352,0.0449821,0.998236 beta-lactamase_2500_D36A,beta-lactamase_2500_36,TEM-1,beta-lactamase_2500,P62593,0.998238,NO,36,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.732,-2.434,-0.298,,0.555,H,A,0.75,1.17,2.26,,77.62,AAP,-1.91167,0.361275,0.00476483,0.998238 beta-lactamase_625_S283M,beta-lactamase_625_283,TEM-1,beta-lactamase_625,P62593,0.998239,NO,283,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.213352,0.0429138,0.998239 beta-lactamase_39_T69V,beta-lactamase_39_69,TEM-1,beta-lactamase_39,P62593,0.99824,NO,69,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-0.973,-3.175,2.202,,,G,A,0.22,-1.24,4.194,,93.01,PPH,-1.01833,0.0495842,0.00127498,0.99824 beta-lactamase_625_L49Y,beta-lactamase_625_49,TEM-1,beta-lactamase_625,P62593,0.998247,NO,49,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.897,-4.158,2.261,,0.131,T,A,0.55,0.04,3.112,,64.69,AHP,-1.99233,0.213352,0.00401477,0.998247 kka2_1:4_F20F,kka2_1:4_20,Kka2,kka2_1:4,P00552,0.998247,NO,20,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-3.354,-3.354,,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.168804,0.00701744,0.998247 beta-lactamase_625_F70M,beta-lactamase_625_70,TEM-1,beta-lactamase_625,P62593,0.998248,NO,70,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.169,-3.002,1.833,,,H,A,0.58,-1.34,1.14,,63.99,PHB,-0.980667,0.213352,0.00193499,0.998248 kka2_1:2_I254C,kka2_1:2_254,Kka2,kka2_1:2,P00552,0.99825,NO,254,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.933,-4.856,2.923,,0.135,H,A,1.52,-0.6,2.562,,71.59,BHH,-1.668,0.295029,0.0132375,0.99825 Pab1_D160N,Pab1_160,Pab1,Pab1,P04147,0.99825,NO,160,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.985,-3.04,2.055,,0.396,B,B,,1.12,,,,PAA,-1.30133,0.175299,0.000311977,0.99825 beta-lactamase_39_T27Y,beta-lactamase_39_27,TEM-1,beta-lactamase_39,P62593,0.998252,NO,27,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.905,-4.144,2.239,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.0495842,0.00306559,0.998252 beta-lactamase_156_T116V,beta-lactamase_156_116,TEM-1,beta-lactamase_156,P62593,0.998254,NO,116,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.28,-3.415,2.135,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.111618,0.00336175,0.998254 beta-lactamase_Q37H,beta-lactamase_37,TEM-1,beta-lactamase,P62593,0.998254,NO,37,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.134,-3.314,1.18,5.69153,0.613,H,A,0.12,1.98,1.318,,73.08,APH,-2.06967,0.221079,0.00425833,0.998254 beta-lactamase_39_T138P,beta-lactamase_39_138,TEM-1,beta-lactamase_39,P62593,0.998255,NO,138,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.506,-3.038,0.532,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.0495842,0.00487868,0.998255 beta-lactamase_625_T198L,beta-lactamase_625_198,TEM-1,beta-lactamase_625,P62593,0.998256,NO,198,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.168,-3.433,1.265,,0.489,,B,0.22,-0.13,0.37,,73.78,HPH,-1.98767,0.213352,0.004311,0.998256 beta-lactamase_625_G265M,beta-lactamase_625_265,TEM-1,beta-lactamase_625,P62593,0.998258,NO,265,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.213352,0.00811926,0.998258 beta-lactamase_156_H151I,beta-lactamase_156_151,TEM-1,beta-lactamase_156,P62593,0.998259,NO,151,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-2.96,-4.091,1.131,,0.594,H,A,0.17,0.1,1.401,,77.62,HBP,-2.34767,0.111618,0.00216946,0.998259 beta-lactamase_625_N50Q,beta-lactamase_625_50,TEM-1,beta-lactamase_625,P62593,0.998261,NO,50,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-2.979,-2.653,-0.326,,0.912,T,A,0.61,1.24,3.446,,77.62,HPP,-2.134,0.213352,0.0047211,0.998261 beta-lactamase_625_T269F,beta-lactamase_625_269,TEM-1,beta-lactamase_625,P62593,0.998261,NO,269,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.213352,0.00950944,0.998261 beta-lactamase_156_V82I,beta-lactamase_156_82,TEM-1,beta-lactamase_156,P62593,0.998262,NO,82,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.325,-2.197,0.872,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.111618,0.00397046,0.998262 beta-lactamase_625_H24T,beta-lactamase_625_24,TEM-1,beta-lactamase_625,P62593,0.998264,NO,24,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-2.481,-2.645,0.164,,,,,,,2.708,,93.01,OBO,-2.0035,0.213352,0.00238894,0.998264 beta-lactamase_156_R91G,beta-lactamase_156_91,TEM-1,beta-lactamase_156,P62593,0.998265,NO,91,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.392,-3.437,2.045,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.111618,0.00380226,0.998265 beta-lactamase_156_E46H,beta-lactamase_156_46,TEM-1,beta-lactamase_156,P62593,0.998268,NO,46,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.94,-4.828,2.888,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.111618,0.00427568,0.998268 hsp90_E590M,hsp90_590,hsp90,hsp90,P02829,0.998268,NO,590,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.818,-3.858,0,4.65049,0.021,H,A,,0.03,,,,HAO,-3.338,0.368192,0.000222939,0.998268 beta-lactamase_156_R41Q,beta-lactamase_156_41,TEM-1,beta-lactamase_156,P62593,0.998271,NO,41,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-0.942,-3.498,2.556,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.111618,0.00123327,0.998271 beta-lactamase_625_E169T,beta-lactamase_625_169,TEM-1,beta-lactamase_625,P62593,0.998272,NO,169,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.23,-2.43,1.2,,0.337,,A,1.04,1,1.806,,73.08,PAH,-1.16533,0.213352,0.00400994,0.998272 beta-lactamase_156_R159V,beta-lactamase_156_159,TEM-1,beta-lactamase_156,P62593,0.998277,NO,159,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-0.94,-3.779,2.839,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.111618,0.00108472,0.998277 beta-lactamase_S221R,beta-lactamase_221,TEM-1,beta-lactamase,P62593,0.998278,NO,221,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.754,-2.83,1.076,5.77407,0.624,H,A,0.74,-0.2,0.383,,74.48,BPH,-1.59967,0.221079,0.0046094,0.998278 beta-lactamase_625_H94E,beta-lactamase_625_94,TEM-1,beta-lactamase_625,P62593,0.998284,NO,94,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-2.5,-2.415,-0.085,,0.776,,B,0.17,1.24,19.42,19.42,77.62,HBH,-1.872,0.213352,0.00389226,0.998284 kka2_1:8_A176A,kka2_1:8_176,Kka2,kka2_1:8,P00552,0.998287,NO,176,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.621,-1.621,,,0.806,H,A,0.46,-0.03,18.904,18.904,65.53,BHB,-2.26667,0.100394,0.0083587,0.998287 kka2_1:8_A176A,kka2_1:8_176,Kka2,kka2_1:8,P00552,0.998287,NO,176,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.621,-1.621,,,0.806,H,A,0.46,-0.03,18.904,18.904,65.53,BHB,-2.26667,0.100394,0.0083587,0.998287 beta-lactamase_156_K109V,beta-lactamase_156_109,TEM-1,beta-lactamase_156,P62593,0.998288,NO,109,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.734,-3.727,1.993,,0.787,G,A,2.34,2.21,6.031,,72.73,ABB,-1.63333,0.111618,0.00462493,0.998288 beta-lactamase_625_G234C,beta-lactamase_625_234,TEM-1,beta-lactamase_625,P62593,0.998289,NO,234,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.62,-5.087,4.467,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.213352,0.000889577,0.998289 beta-lactamase_156_P25A,beta-lactamase_156_25,TEM-1,beta-lactamase_156,P62593,0.998295,NO,25,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.526,-2.222,0.696,,0.624,H,A,0.52,0.14,1.079,,73.08,BOA,-2.15367,0.111618,0.00347571,0.998295 beta-lactamase_625_V157N,beta-lactamase_625_157,TEM-1,beta-lactamase_625,P62593,0.998303,NO,157,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.751,-3.925,2.174,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.213352,0.00506849,0.998303 beta-lactamase_156_L218V,beta-lactamase_156_218,TEM-1,beta-lactamase_156,P62593,0.998304,NO,218,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.391,-3.3,1.909,,,I,b,0.55,-0.53,17.202,17.202,74.48,OHH,-1.58867,0.111618,0.00618274,0.998304 beta-lactamase_39_R81Y,beta-lactamase_39_81,TEM-1,beta-lactamase_39,P62593,0.998304,NO,81,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.466,-4.271,2.805,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.0495842,0.00499763,0.998304 beta-lactamase_39_W163Y,beta-lactamase_39_163,TEM-1,beta-lactamase_39,P62593,0.998304,NO,163,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-1.843,-3.906,2.063,,0.467,,B,0.47,-0.5,15.095,15.095,63.99,BHA,-1.269,0.0495842,0.00418955,0.998304 beta-lactamase_2500_D113E,beta-lactamase_2500_113,TEM-1,beta-lactamase_2500,P62593,0.998305,NO,113,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.829,-2.32,0.491,,0.665,T,A,0.75,0.91,21.104,21.104,73.08,PAO,-1.703,0.361275,0.00474112,0.998305 beta-lactamase_2500_A84D,beta-lactamase_2500_84,TEM-1,beta-lactamase_2500,P62593,0.998308,NO,84,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.651,-2.92,1.269,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.361275,0.00503822,0.998308 kka2_1:4_A247A,kka2_1:4_247,Kka2,kka2_1:4,P00552,0.998317,NO,247,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.459,-2.459,,,1.01,S,A,0.46,0.65,,,92.05,HHH,-2.197,0.168804,0.0102428,0.998317 kka2_1:4_Q252Q,kka2_1:4_252,Kka2,kka2_1:4,P00552,0.998317,NO,252,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.63,-2.63,,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.168804,0.0121001,0.998317 beta-lactamase_156_G114Q,beta-lactamase_156_114,TEM-1,beta-lactamase_156,P62593,0.998318,NO,114,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.094,-4.039,2.945,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.111618,0.00224919,0.998318 kka2_1:2_D33D,kka2_1:2_33,Kka2,kka2_1:2,P00552,0.998319,NO,33,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.186,-2.186,,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.295029,0.00633568,0.998319 beta-lactamase_625_K53W,beta-lactamase_625_53,TEM-1,beta-lactamase_625,P62593,0.99832,NO,53,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-2.313,-2.612,0.299,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.213352,0.00383383,0.99832 beta-lactamase_2500_T138S,beta-lactamase_2500_138,TEM-1,beta-lactamase_2500,P62593,0.998324,NO,138,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.506,-2.455,-0.051,,0.662,H,A,0.22,-0.03,30.445,30.445,73.78,HPP,-1.81233,0.361275,0.00487868,0.998324 beta-lactamase_625_E279L,beta-lactamase_625_279,TEM-1,beta-lactamase_625,P62593,0.998326,NO,279,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.213352,0.0192826,0.998326 beta-lactamase_2500_L196M,beta-lactamase_2500_196,TEM-1,beta-lactamase_2500,P62593,0.998328,NO,196,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-2.478,-3.442,0.964,,0.518,S,A,0.55,1.35,7.897,,77.62,AHH,-1.839,0.361275,0.00512144,0.998328 beta-lactamase_2500_D33A,beta-lactamase_2500_33,TEM-1,beta-lactamase_2500,P62593,0.998335,NO,33,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.321,-2.241,-0.08,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.361275,0.00435556,0.998335 beta-lactamase_2500_A282H,beta-lactamase_2500_282,TEM-1,beta-lactamase_2500,P62593,0.998337,NO,282,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.361275,0.0449821,0.998337 beta-lactamase_625_G194D,beta-lactamase_625_194,TEM-1,beta-lactamase_625,P62593,0.998338,NO,194,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.396,-2.314,0.918,,0.276,S,b,0.29,0.36,3.593,,67.83,POA,-1.832,0.213352,0.00392163,0.998338 beta-lactamase_625_H94F,beta-lactamase_625_94,TEM-1,beta-lactamase_625,P62593,0.998342,NO,94,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-2.5,-4.323,1.823,,0.776,,B,0.17,1.24,19.42,19.42,77.62,HBH,-1.872,0.213352,0.00389226,0.998342 kka2_1:2_M178M,kka2_1:2_178,Kka2,kka2_1:2,P00552,0.998347,NO,178,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-3.206,-3.206,,,0.554,.,b,0.55,0.68,3.152,,71.59,BHO,-2.154,0.295029,0.00717253,0.998347 kka2_1:4_Q155Q,kka2_1:4_155,Kka2,kka2_1:4,P00552,0.998349,NO,155,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.606,-2.606,,,0.525,T,A,0.64,1.49,1.592,,63.64,APA,-1.726,0.168804,0.00641853,0.998349 beta-lactamase_156_V101M,beta-lactamase_156_101,TEM-1,beta-lactamase_156,P62593,0.998352,NO,101,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.295,-2.812,1.517,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.111618,0.00374492,0.998352 beta-lactamase_0_G194L,beta-lactamase_0_194,TEM-1,beta-lactamase_0,P62593,0.998357,NO,194,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.396,-3.731,2.335,,0.276,S,b,0.29,0.36,3.017,,67.83,POA,-1.832,0.0500837,0.00392163,0.998357 beta-lactamase_156_L150V,beta-lactamase_156_150,TEM-1,beta-lactamase_156,P62593,0.998357,NO,150,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.326,-2.348,1.022,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.111618,0.00463171,0.998357 beta-lactamase_39_S57Y,beta-lactamase_39_57,TEM-1,beta-lactamase_39,P62593,0.998359,NO,57,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.918,-4.294,2.376,,0.352,E,B,0.27,-0.18,2.3,,72.73,APH,-2.29167,0.0495842,0.00492804,0.998359 kka2_1:1_C31C,kka2_1:1_31,Kka2,kka2_1:1,P00552,0.998359,NO,31,C,C,CC,Special,Special,5.07,5.07,0,0,121,121,0,108.5,108.5,0,-2.246,-2.246,,,1.152,S,b,0.46,4.16,8.272,,63.26,OOP,-1.21533,0.520039,0.00681582,0.998359 beta-lactamase_156_M127F,beta-lactamase_156_127,TEM-1,beta-lactamase_156,P62593,0.99836,NO,127,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-2.251,-3.969,1.718,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.111618,0.00437927,0.99836 beta-lactamase_39_A40Y,beta-lactamase_39_40,TEM-1,beta-lactamase_39,P62593,0.99836,NO,40,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.402,-4.322,2.92,,0.155,S,B,0.46,0.21,0.783,,73.78,OHB,-1.40267,0.0495842,0.00490026,0.99836 beta-lactamase_0_F64C,beta-lactamase_0_64,TEM-1,beta-lactamase_0,P62593,0.998364,NO,64,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-0.841,-4.862,4.021,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.0500837,0.000947691,0.998364 beta-lactamase_39_R220Q,beta-lactamase_39_220,TEM-1,beta-lactamase_39,P62593,0.99837,NO,220,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-0.942,-3.517,2.575,,0.295,I,A,1.2,-0.76,1.596,,74.48,HBP,-1.33633,0.0495842,0.00232421,0.99837 beta-lactamase_39_T198W,beta-lactamase_39_198,TEM-1,beta-lactamase_39,P62593,0.998373,NO,198,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.168,-5.419,3.251,,0.489,,B,0.22,-0.13,3.614,,73.78,HPH,-1.98767,0.0495842,0.004311,0.998373 beta-lactamase_156_S283H,beta-lactamase_156_283,TEM-1,beta-lactamase_156,P62593,0.998374,NO,283,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.111618,0.0429138,0.998374 beta-lactamase_625_A77G,beta-lactamase_625_77,TEM-1,beta-lactamase_625,P62593,0.998375,NO,77,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.234,-2.31,1.076,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.213352,0.00282362,0.998375 kka2_1:2_Q42Q,kka2_1:2_42,Kka2,kka2_1:2,P00552,0.998376,NO,42,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.907,-2.907,,,1.044,T,B,0.64,-0.8,2.792,,71.59,HPO,-2.12433,0.295029,0.00679212,0.998376 beta-lactamase_156_L191F,beta-lactamase_156_191,TEM-1,beta-lactamase_156,P62593,0.998377,NO,191,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.087,-2.754,1.667,,,H,A,0.55,0.09,1.372,,63.29,BHH,-1.445,0.111618,0.00263549,0.998377 beta-lactamase_39_L223G,beta-lactamase_39_223,TEM-1,beta-lactamase_39,P62593,0.998378,NO,223,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.055,-3.765,2.71,,0.27,,B,0.55,0.09,1.511,,74.48,HHO,-1.35033,0.0495842,0.00372793,0.998378 beta-lactamase_39_T269P,beta-lactamase_39_269,TEM-1,beta-lactamase_39,P62593,0.998378,NO,269,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.156,,,,0.646,H,A,0.53,0.4,3.889,,77.62,HPH,-1.96733,0.0495842,0.00950944,0.998378 beta-lactamase_2500_G90D,beta-lactamase_2500_90,TEM-1,beta-lactamase_2500,P62593,0.998379,NO,90,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-2.091,-2.02,-0.071,,0.598,T,A,0.29,0.32,1.2,,77.62,HOB,-1.52633,0.361275,0.00490273,0.998379 beta-lactamase_625_R189W,beta-lactamase_625_189,TEM-1,beta-lactamase_625,P62593,0.998379,NO,189,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.844,-5.37,3.526,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.213352,0.0050699,0.998379 kka2_1:2_A65A,kka2_1:2_65,Kka2,kka2_1:2,P00552,0.998382,NO,65,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.744,-1.744,,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.295029,0.00709258,0.998382 beta-lactamase_625_T193N,beta-lactamase_625_193,TEM-1,beta-lactamase_625,P62593,0.998384,NO,193,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.914,-2.715,0.801,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.213352,0.00482669,0.998384 beta-lactamase_39_G236D,beta-lactamase_39_236,TEM-1,beta-lactamase_39,P62593,0.998387,NO,236,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.784,-3.513,2.729,,0.241,,b,0.29,-0.59,1.883,,64.69,HOO,-1.025,0.0495842,0.00162372,0.998387 beta-lactamase_156_H156K,beta-lactamase_156_156,TEM-1,beta-lactamase_156,P62593,0.998388,NO,156,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-3.156,-2.967,-0.189,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.111618,0.00468596,0.998388 beta-lactamase_A246V,beta-lactamase_246,TEM-1,beta-lactamase,P62593,0.998394,NO,246,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.121,-1.76,-0.361,4.78979,0.01,E,B,0.52,-1.01,1.26,,73.78,HHH,-1.55633,0.221079,0.00569458,0.998394 kka2_1:2_A176A,kka2_1:2_176,Kka2,kka2_1:2,P00552,0.998395,NO,176,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.621,-1.621,,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.295029,0.0083587,0.998395 kka2_1:2_S114S,kka2_1:2_114,Kka2,kka2_1:2,P00552,0.998395,NO,114,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.527,-2.527,,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.295029,0.00705262,0.998395 beta-lactamase_39_L28K,beta-lactamase_39_28,TEM-1,beta-lactamase_39,P62593,0.998397,NO,28,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.579,-3.608,2.029,,0.277,H,A,0.55,-0.16,3.262,,93.01,PHH,-2.11333,0.0495842,0.00359321,0.998397 kka2_1:2_L165L,kka2_1:2_165,Kka2,kka2_1:2,P00552,0.998404,NO,165,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-2.453,-2.453,,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.295029,0.00801161,0.998404 beta-lactamase_0_E210Y,beta-lactamase_0_210,TEM-1,beta-lactamase_0,P62593,0.998405,NO,210,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.319,-4.214,1.895,,0.476,H,A,1.04,0.75,3.618,,77.62,HAH,-1.88567,0.0500837,0.00663582,0.998405 kka2_1:4_D23M,kka2_1:4_23,Kka2,kka2_1:4,P00552,0.998405,NO,23,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.459,-4.807,2.348,,0.695,E,B,0.75,-0.65,2.416,,65.53,HAH,-1.94033,0.168804,0.007195,0.998405 beta-lactamase_156_P25S,beta-lactamase_156_25,TEM-1,beta-lactamase_156,P62593,0.998406,NO,25,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.526,-3.274,1.748,,0.624,H,A,0.52,0.14,1.079,,73.08,BOA,-2.15367,0.111618,0.00347571,0.998406 beta-lactamase_39_S283N,beta-lactamase_39_283,TEM-1,beta-lactamase_39,P62593,0.998407,NO,283,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.0495842,0.0429138,0.998407 beta-lactamase_156_L28A,beta-lactamase_156_28,TEM-1,beta-lactamase_156,P62593,0.998408,NO,28,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.579,-2.126,0.547,,0.277,H,A,0.55,-0.16,3.262,,93.01,PHH,-2.11333,0.111618,0.00359321,0.998408 beta-lactamase_39_G142Y,beta-lactamase_39_142,TEM-1,beta-lactamase_39,P62593,0.998408,NO,142,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.707,-4.385,3.678,,0.034,,p,0.29,-0.64,1.947,,64.69,OOO,-0.834,0.0495842,0.00060149,0.998408 beta-lactamase_T198K,beta-lactamase_198,TEM-1,beta-lactamase,P62593,0.998408,NO,198,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.168,-2.548,0.38,4.9209,0.489,,B,0.69,-0.13,0.37,,73.78,HPH,-1.98767,0.221079,0.004311,0.998408 beta-lactamase_156_Q88P,beta-lactamase_156_88,TEM-1,beta-lactamase_156,P62593,0.998411,NO,88,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.086,-3.948,1.862,,0.807,,B,0.64,2.03,0.911,,77.62,APH,-1.53433,0.111618,0.00504167,0.998411 beta-lactamase_39_T147D,beta-lactamase_39_147,TEM-1,beta-lactamase_39,P62593,0.998413,NO,147,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.149,-3.491,2.342,,0.281,H,A,0.22,-0.68,13.843,13.843,64.34,HPH,-1.456,0.0495842,0.00226017,0.998413 kka2_1:2_Q252Q,kka2_1:2_252,Kka2,kka2_1:2,P00552,0.998414,NO,252,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.63,-2.63,,,0.906,H,A,0.64,0.35,5.613,,92.05,PPB,-2.20733,0.295029,0.0121001,0.998414 kka2_1:4_T146T,kka2_1:4_146,Kka2,kka2_1:4,P00552,0.998414,NO,146,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.978,-2.978,,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.168804,0.00606474,0.998414 beta-lactamase_156_R159E,beta-lactamase_156_159,TEM-1,beta-lactamase_156,P62593,0.998417,NO,159,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-0.94,-3.241,2.301,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.111618,0.00108472,0.998417 beta-lactamase_39_Q276C,beta-lactamase_39_276,TEM-1,beta-lactamase_39,P62593,0.998419,NO,276,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.0495842,0.0191712,0.998419 kka2_1:1_A79A,kka2_1:1_79,Kka2,kka2_1:1,P00552,0.998422,NO,79,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.368,-2.368,,,0.563,.,B,0.46,-0.43,7.792,7.792,71.59,HHH,-1.752,0.520039,0.00664821,0.998422 kka2_1:4_F37H,kka2_1:4_37,Kka2,kka2_1:4,P00552,0.998423,NO,37,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.427,-2.73,1.303,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.168804,0.00586193,0.998423 beta-lactamase_625_E166N,beta-lactamase_625_166,TEM-1,beta-lactamase_625,P62593,0.998425,NO,166,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.756,-3.709,1.953,,0.508,G,A,1.04,1.05,2.124,,73.08,OAH,-1.42233,0.213352,0.00512989,0.998425 beta-lactamase_156_E169G,beta-lactamase_156_169,TEM-1,beta-lactamase_156,P62593,0.998428,NO,169,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.23,-3.348,2.118,,0.337,,A,1.04,1,3.516,,73.08,PAH,-1.16533,0.111618,0.00400994,0.998428 beta-lactamase_A276R,beta-lactamase_276,TEM-1,beta-lactamase,P62593,0.998428,NO,276,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.144,-2.742,1.598,5.1387,0.117,H,A,0.52,-0.84,1.283,,44.06,HHA,-1.47,0.221079,0.0191712,0.998428 beta-lactamase_39_T131W,beta-lactamase_39_131,TEM-1,beta-lactamase_39,P62593,0.998433,NO,131,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.328,-5.315,3.987,,,H,A,0.22,-0.69,3.306,,67.48,PPH,-1.00867,0.0495842,0.00345886,0.998433 kka2_1:2_D180D,kka2_1:2_180,Kka2,kka2_1:2,P00552,0.998433,NO,180,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.416,-2.416,,,1.03,S,a,0.75,1.5,1.27,,71.59,OAO,-2.02933,0.295029,0.00756412,0.998433 kka2_1:4_E231E,kka2_1:4_231,Kka2,kka2_1:4,P00552,0.998435,NO,231,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.002,-2.002,,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.168804,0.00732383,0.998435 beta-lactamase_156_L111A,beta-lactamase_156_111,TEM-1,beta-lactamase_156,P62593,0.998436,NO,111,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.76,-2.229,0.469,,0.328,T,A,0.55,0.93,2.26,,64.34,BHP,-1.884,0.111618,0.00480671,0.998436 kka2_1:8_E96E,kka2_1:8_96,Kka2,kka2_1:8,P00552,0.998436,NO,96,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.573,-2.573,,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.100394,0.00369441,0.998436 kka2_1:8_E96E,kka2_1:8_96,Kka2,kka2_1:8,P00552,0.998436,NO,96,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.573,-2.573,,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.100394,0.00369441,0.998436 beta-lactamase_0_L89M,beta-lactamase_0_89,TEM-1,beta-lactamase_0,P62593,0.99844,NO,89,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.096,-2.928,1.832,,0.168,T,A,0.55,0.63,2.373,,64.34,PHO,-1.75767,0.0500837,0.00207068,0.99844 beta-lactamase_K252S,beta-lactamase_252,TEM-1,beta-lactamase,P62593,0.99844,NO,252,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.94,-2.802,0.862,5.56823,0.766,,B,1.82,1.16,21.796,21.796,67.83,OBO,-2.03333,0.221079,0.00575769,0.99844 kka2_1:2_T125T,kka2_1:2_125,Kka2,kka2_1:2,P00552,0.998442,NO,125,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.622,-2.622,,,0.791,T,A,0.22,0.33,2.029,,92.05,BPH,-1.56933,0.295029,0.00821755,0.998442 beta-lactamase_625_L199H,beta-lactamase_625_199,TEM-1,beta-lactamase_625,P62593,0.998447,NO,199,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-2.942,-4.8,1.858,,0.832,H,A,0.55,0.42,1.552,,77.62,PHH,-2.32933,0.213352,0.0048649,0.998447 beta-lactamase_625_N50P,beta-lactamase_625_50,TEM-1,beta-lactamase_625,P62593,0.998451,NO,50,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-2.979,-3.95,0.971,,0.912,T,A,0.61,1.24,3.446,,77.62,HPP,-2.134,0.213352,0.0047211,0.998451 beta-lactamase_625_G39D,beta-lactamase_625_39,TEM-1,beta-lactamase_625,P62593,0.998453,NO,39,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.864,-2.194,0.33,,0.701,T,L,0.29,0.47,29.926,29.926,77.62,HOH,-1.53633,0.213352,0.00487611,0.998453 beta-lactamase_39_P224Q,beta-lactamase_39_224,TEM-1,beta-lactamase_39,P62593,0.998454,NO,224,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.893,-3.868,2.975,,0.383,,B,0.52,-0.3,3.169,,74.48,HOH,-1.26433,0.0495842,0.00189564,0.998454 beta-lactamase_2500_K286H,beta-lactamase_2500_286,TEM-1,beta-lactamase_2500,P62593,0.998456,NO,286,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.361275,,0.998456 beta-lactamase_625_A222N,beta-lactamase_625_222,TEM-1,beta-lactamase_625,P62593,0.998459,NO,222,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.103,-3.751,1.648,,0.233,H,A,0.46,-0.25,1.448,,77.62,PHH,-1.63733,0.213352,0.00466094,0.998459 beta-lactamase_156_M66F,beta-lactamase_156_66,TEM-1,beta-lactamase_156,P62593,0.99846,NO,66,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.362,-3.731,2.369,,0.013,,A,0.55,-0.7,1.94,,73.08,OHH,-1.49567,0.111618,0.00412876,0.99846 kka2_1:2_A166A,kka2_1:2_166,Kka2,kka2_1:2,P00552,0.998464,NO,166,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.407,-2.407,,,0.534,.,B,0.46,1.03,23.175,23.175,71.59,HHO,-2.421,0.295029,0.00799912,0.998464 beta-lactamase_39_K30L,beta-lactamase_39_30,TEM-1,beta-lactamase_39,P62593,0.998466,NO,30,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-2.307,-3.404,1.097,,0.142,H,A,2.34,-0.65,6.717,,93.01,HBH,-2.32833,0.0495842,0.00448593,0.998466 beta-lactamase_39_T263Q,beta-lactamase_39_263,TEM-1,beta-lactamase_39,P62593,0.998466,NO,263,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.0495842,0.0110582,0.998466 kka2_1:4_A13A,kka2_1:4_13,Kka2,kka2_1:4,P00552,0.998468,NO,13,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.248,-2.248,,,0.689,G,A,0.46,0.99,,,92.05,OHH,-1.646,0.168804,0.00784241,0.998468 beta-lactamase_625_M270D,beta-lactamase_625_270,TEM-1,beta-lactamase_625,P62593,0.998471,NO,270,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.213352,0.00767762,0.998471 beta-lactamase_625_M270T,beta-lactamase_625_270,TEM-1,beta-lactamase_625,P62593,0.998474,NO,270,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.213352,0.00767762,0.998474 beta-lactamase_2500_A200Q,beta-lactamase_2500_200,TEM-1,beta-lactamase_2500,P62593,0.998476,NO,200,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.878,-3.113,1.235,,0.757,H,A,0.46,-0.19,0.436,,77.62,HHP,-2.001,0.361275,0.0060056,0.998476 beta-lactamase_625_S51E,beta-lactamase_625_51,TEM-1,beta-lactamase_625,P62593,0.998476,NO,51,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.526,-3.428,1.902,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.213352,0.00504821,0.998476 beta-lactamase_625_P217D,beta-lactamase_625_217,TEM-1,beta-lactamase_625,P62593,0.998477,NO,217,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-2.062,-2.498,0.436,,0.496,I,A,0.52,-0.33,1.087,,74.48,OOH,-1.64333,0.213352,0.00463211,0.998477 kka2_1:4_A168A,kka2_1:4_168,Kka2,kka2_1:4,P00552,0.998479,NO,168,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.989,-1.989,,,0.67,H,A,0.46,0.15,,,64.39,OHA,-2.12933,0.168804,0.00806773,0.998479 beta-lactamase_156_A235S,beta-lactamase_156_235,TEM-1,beta-lactamase_156,P62593,0.99848,NO,235,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.266,-2.058,0.792,,0.32,E,B,0.46,-0.86,1.344,,50,OHO,-0.89,0.111618,0.00493474,0.99848 beta-lactamase_625_K53T,beta-lactamase_625_53,TEM-1,beta-lactamase_625,P62593,0.99848,NO,53,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-2.313,-2.702,0.389,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.213352,0.00383383,0.99848 beta-lactamase_39_H24I,beta-lactamase_39_24,TEM-1,beta-lactamase_39,P62593,0.998484,NO,24,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-2.481,-3.874,1.393,,,,,,,2.708,,93.01,OBO,-2.0035,0.0495842,0.00238894,0.998484 beta-lactamase_156_V72S,beta-lactamase_156_72,TEM-1,beta-lactamase_156,P62593,0.998485,NO,72,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.658,-3.477,1.819,,,H,A,0.44,-1.03,1.92,,65.73,BHH,-1.32167,0.111618,0.00501194,0.998485 beta-lactamase_625_H24R,beta-lactamase_625_24,TEM-1,beta-lactamase_625,P62593,0.998485,NO,24,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-2.481,-3.749,1.268,,,,,,,2.708,,93.01,OBO,-2.0035,0.213352,0.00238894,0.998485 kka2_1:8_G234G,kka2_1:8_234,Kka2,kka2_1:8,P00552,0.998485,NO,234,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-2.9,-2.9,,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.100394,0.00984449,0.998485 kka2_1:8_G234G,kka2_1:8_234,Kka2,kka2_1:8,P00552,0.998485,NO,234,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-2.9,-2.9,,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.100394,0.00984449,0.998485 beta-lactamase_156_G76I,beta-lactamase_156_76,TEM-1,beta-lactamase_156,P62593,0.998487,NO,76,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.189,-3.948,2.759,,,H,A,0.29,-0.67,3.059,,67.83,OOH,-1.22267,0.111618,0.00476637,0.998487 beta-lactamase_39_R162L,beta-lactamase_39_162,TEM-1,beta-lactamase_39,P62593,0.998491,NO,162,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.016,-2.541,1.525,,0.124,S,B,1.2,-0.37,31.656,31.656,64.69,ABH,-1.25,0.0495842,0.000561334,0.998491 beta-lactamase_39_L223R,beta-lactamase_39_223,TEM-1,beta-lactamase_39,P62593,0.998492,NO,223,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.055,-4.022,2.967,,0.27,,B,0.55,0.09,1.511,,74.48,HHO,-1.35033,0.0495842,0.00372793,0.998492 kka2_1:4_E149E,kka2_1:4_149,Kka2,kka2_1:4,P00552,0.998493,NO,149,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.994,-1.994,,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.168804,0.00803343,0.998493 beta-lactamase_156_M180F,beta-lactamase_156_180,TEM-1,beta-lactamase_156,P62593,0.998494,NO,180,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-2.795,-3.981,1.186,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.111618,0.00552048,0.998494 beta-lactamase_2500_L196G,beta-lactamase_2500_196,TEM-1,beta-lactamase_2500,P62593,0.998494,NO,196,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-2.478,-2.91,0.432,,0.518,S,A,0.55,1.35,7.897,,77.62,AHH,-1.839,0.361275,0.00512144,0.998494 kka2_1:4_Q4Q,kka2_1:4_4,Kka2,kka2_1:4,P00552,0.998495,NO,4,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.361,-2.361,,,,,,,,2.026,,71.59,APA,-1.95533,0.168804,0.00239179,0.998495 beta-lactamase_156_E210R,beta-lactamase_156_210,TEM-1,beta-lactamase_156,P62593,0.998505,NO,210,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.319,-3.045,0.726,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.111618,0.00663582,0.998505 beta-lactamase_156_V72A,beta-lactamase_156_72,TEM-1,beta-lactamase_156,P62593,0.998505,NO,72,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.658,-1.729,0.071,,,H,A,0.44,-1.03,1.92,,65.73,BHH,-1.32167,0.111618,0.00501194,0.998505 beta-lactamase_156_P250Y,beta-lactamase_156_250,TEM-1,beta-lactamase_156,P62593,0.998507,NO,250,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.111618,0.00550899,0.998507 beta-lactamase_0_L47I,beta-lactamase_0_47,TEM-1,beta-lactamase_0,P62593,0.99851,NO,47,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.876,-2.384,0.508,,0.007,E,B,0.55,0.2,1.024,,67.83,AHA,-1.639,0.0500837,0.00439844,0.99851 beta-lactamase_39_A200H,beta-lactamase_39_200,TEM-1,beta-lactamase_39,P62593,0.99851,NO,200,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.878,-4.732,2.854,,0.757,H,A,0.46,-0.19,1.54,,77.62,HHP,-2.001,0.0495842,0.0060056,0.99851 beta-lactamase_625_G253A,beta-lactamase_625_253,TEM-1,beta-lactamase_625,P62593,0.998512,NO,253,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.213352,0.00786358,0.998512 kka2_1:2_R143R,kka2_1:2_143,Kka2,kka2_1:2,P00552,0.998512,NO,143,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.525,-2.525,,,0.325,H,A,0.16,1.22,14.853,14.853,65.53,ABH,-1.86833,0.295029,0.00662247,0.998512 beta-lactamase_156_I45A,beta-lactamase_156_45,TEM-1,beta-lactamase_156,P62593,0.998514,NO,45,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-2.421,-2.001,-0.42,,,E,B,0.48,-0.3,2.256,,77.62,HHA,-2.30267,0.111618,0.00452842,0.998514 beta-lactamase_156_V259T,beta-lactamase_156_259,TEM-1,beta-lactamase_156,P62593,0.998514,NO,259,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.111618,0.0070773,0.998514 kka2_1:2_A14A,kka2_1:2_14,Kka2,kka2_1:2,P00552,0.998515,NO,14,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.837,-1.837,,,0.728,G,A,0.46,0.7,0.36,,71.59,HHH,-1.82567,0.295029,0.00706614,0.998515 beta-lactamase_39_A84T,beta-lactamase_39_84,TEM-1,beta-lactamase_39,P62593,0.998518,NO,84,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.651,-2.88,1.229,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.0495842,0.00503822,0.998518 beta-lactamase_625_A148T,beta-lactamase_625_148,TEM-1,beta-lactamase_625,P62593,0.998518,NO,148,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.757,-2.508,0.751,,0.379,H,A,0.46,-0.55,1.359,,72.73,PHH,-1.40167,0.213352,0.00547053,0.998518 kka2_1:2_A25A,kka2_1:2_25,Kka2,kka2_1:2,P00552,0.998518,NO,25,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.496,-2.496,,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.295029,0.00595636,0.998518 kka2_1:2_D23D,kka2_1:2_23,Kka2,kka2_1:2,P00552,0.998521,NO,23,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.459,-2.459,,,0.695,E,B,0.75,-0.65,18.207,18.207,65.53,HAH,-1.94033,0.295029,0.007195,0.998521 kka2_1:2_H106H,kka2_1:2_106,Kka2,kka2_1:2,P00552,0.998521,NO,106,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-3.13,-3.13,,,1.065,.,a,0.17,-0.95,2.53,,71.59,PBH,-2.10433,0.295029,0.00730778,0.998521 PSD95pdz3_N326Y,PSD95pdz3_326,PSD95pdz3,PSD95pdz3,P31016,0.998523,NO,326,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-1.41,-3.844,2.434,5.52537,,,,,19.0688,,,,HPH,-1.52133,0.0758425,0.00101078,0.998523 beta-lactamase_156_I206K,beta-lactamase_156_206,TEM-1,beta-lactamase_156,P62593,0.998524,NO,206,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-2.429,-3.632,1.203,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.111618,0.00528934,0.998524 beta-lactamase_39_E210T,beta-lactamase_39_210,TEM-1,beta-lactamase_39,P62593,0.998524,NO,210,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.319,-2.842,0.523,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.0495842,0.00663582,0.998524 kka2_1:2_A9A,kka2_1:2_9,Kka2,kka2_1:2,P00552,0.998524,NO,9,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.079,-2.079,,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.295029,0.00273264,0.998524 beta-lactamase_156_E210S,beta-lactamase_156_210,TEM-1,beta-lactamase_156,P62593,0.998527,NO,210,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.319,-2.669,0.35,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.111618,0.00663582,0.998527 beta-lactamase_156_L197H,beta-lactamase_156_197,TEM-1,beta-lactamase_156,P62593,0.998531,NO,197,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.853,-4.903,4.05,,0.007,S,B,0.55,0.33,1.58,,60.14,HHP,-1.833,0.111618,0.00144602,0.998531 beta-lactamase_156_N98D,beta-lactamase_156_98,TEM-1,beta-lactamase_156,P62593,0.998535,NO,98,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-2.973,-2.35,-0.623,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.111618,0.00505389,0.998535 beta-lactamase_Q97G,beta-lactamase_97,TEM-1,beta-lactamase,P62593,0.998539,NO,97,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.072,-2.827,0.755,6.30204,0.823,G,A,1.1,2.42,1.157,,77.62,PPP,-2.43833,0.221079,0.0045116,0.998539 beta-lactamase_625_A278Y,beta-lactamase_625_278,TEM-1,beta-lactamase_625,P62593,0.998541,NO,278,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.213352,0.0310297,0.998541 beta-lactamase_625_T198E,beta-lactamase_625_198,TEM-1,beta-lactamase_625,P62593,0.998542,NO,198,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.168,-3.379,1.211,,0.489,,B,0.22,-0.13,0.37,,73.78,HPH,-1.98767,0.213352,0.004311,0.998542 beta-lactamase_2500_D36K,beta-lactamase_2500_36,TEM-1,beta-lactamase_2500,P62593,0.998544,NO,36,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.732,-2.543,-0.189,,0.555,H,A,0.75,1.17,2.26,,77.62,AAP,-1.91167,0.361275,0.00476483,0.998544 beta-lactamase_625_S221E,beta-lactamase_625_221,TEM-1,beta-lactamase_625,P62593,0.998545,NO,221,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.754,-3.442,1.688,,0.624,H,A,0.27,-0.2,1.495,,74.48,BPH,-1.59967,0.213352,0.0046094,0.998545 beta-lactamase_39_K286P,beta-lactamase_39_286,TEM-1,beta-lactamase_39,P62593,0.99855,NO,286,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.0495842,,0.99855 beta-lactamase_625_S51G,beta-lactamase_625_51,TEM-1,beta-lactamase_625,P62593,0.998551,NO,51,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.526,-2.569,1.043,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.213352,0.00504821,0.998551 beta-lactamase_156_A278N,beta-lactamase_156_278,TEM-1,beta-lactamase_156,P62593,0.998554,NO,278,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.111618,0.0310297,0.998554 beta-lactamase_156_N274Q,beta-lactamase_156_274,TEM-1,beta-lactamase_156,P62593,0.998554,NO,274,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-2.082,-3.838,1.756,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.111618,0.0110418,0.998554 beta-lactamase_2500_K144N,beta-lactamase_2500_144,TEM-1,beta-lactamase_2500,P62593,0.998556,NO,144,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-2.388,-3.043,0.655,,0.863,H,A,2.34,1.27,0.515,,77.62,OBA,-1.904,0.361275,0.00481141,0.998556 Pab1_E174Q,Pab1_174,Pab1,Pab1,P04147,0.998556,NO,174,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.422,-3.307,1.885,,0.578,S,A,,0.38,,,,HAA,-1.65133,0.175299,0.00077863,0.998556 beta-lactamase_2500_L199H,beta-lactamase_2500_199,TEM-1,beta-lactamase_2500,P62593,0.998562,NO,199,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-2.942,-4.8,1.858,,0.832,H,A,0.55,0.42,15.504,15.504,77.62,PHH,-2.32933,0.361275,0.0048649,0.998562 kka2_1:4_L102V,kka2_1:4_102,Kka2,kka2_1:4,P00552,0.998562,NO,102,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.804,-2.905,2.101,,,T,A,0.55,-1.17,0.65,,42.42,AHH,-1.398,0.168804,0.00201332,0.998562 kka2_1:8_C31Y,kka2_1:8_31,Kka2,kka2_1:8,P00552,0.998568,NO,31,C,Y,CY,Special,Hydrophobic,5.07,5.66,0.59,194,121,181,60,108.5,193.6,85.1,-2.246,-4.264,2.018,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.100394,0.00681582,0.998568 kka2_1:8_C31Y,kka2_1:8_31,Kka2,kka2_1:8,P00552,0.998568,NO,31,C,Y,CY,Special,Hydrophobic,5.07,5.66,0.59,194,121,181,60,108.5,193.6,85.1,-2.246,-4.264,2.018,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.100394,0.00681582,0.998568 beta-lactamase_2500_L199E,beta-lactamase_2500_199,TEM-1,beta-lactamase_2500,P62593,0.998578,NO,199,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-2.942,-2.604,-0.338,,0.832,H,A,0.55,0.42,15.504,15.504,77.62,PHH,-2.32933,0.361275,0.0048649,0.998578 beta-lactamase_625_P60Y,beta-lactamase_625_60,TEM-1,beta-lactamase_625,P62593,0.998578,NO,60,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-2.469,-4.292,1.823,,0.256,T,A,0.52,-0.56,3.653,,77.62,BOA,-1.97633,0.213352,0.00521318,0.998578 beta-lactamase_156_A77Y,beta-lactamase_156_77,TEM-1,beta-lactamase_156,P62593,0.998579,NO,77,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.234,-4.173,2.939,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.111618,0.00282362,0.998579 kka2_1:4_E199E,kka2_1:4_199,Kka2,kka2_1:4,P00552,0.998579,NO,199,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.234,-2.234,,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.168804,0.00854122,0.998579 beta-lactamase_156_G281V,beta-lactamase_156_281,TEM-1,beta-lactamase_156,P62593,0.998582,NO,281,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.111618,0.0406482,0.998582 beta-lactamase_625_M153C,beta-lactamase_625_153,TEM-1,beta-lactamase_625,P62593,0.998584,NO,153,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-3.193,-4.79,1.597,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.213352,0.00509109,0.998584 beta-lactamase_156_E238V,beta-lactamase_156_238,TEM-1,beta-lactamase_156,P62593,0.998585,NO,238,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.111618,0.00743256,0.998585 beta-lactamase_625_L49M,beta-lactamase_625_49,TEM-1,beta-lactamase_625,P62593,0.998586,NO,49,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.897,-4.411,2.514,,0.131,T,A,0.55,0.04,3.112,,64.69,AHP,-1.99233,0.213352,0.00401477,0.998586 kka2_1:4_L7L,kka2_1:4_7,Kka2,kka2_1:4,P00552,0.998586,NO,7,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.926,-1.926,,,,,,,,3.012,,71.59,OHB,-2.12333,0.168804,0.00269456,0.998586 kka2_1:4_Q42Q,kka2_1:4_42,Kka2,kka2_1:4,P00552,0.998586,NO,42,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.907,-2.907,,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.168804,0.00679212,0.998586 beta-lactamase_156_R162G,beta-lactamase_156_162,TEM-1,beta-lactamase_156,P62593,0.998587,NO,162,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.016,-3.445,2.429,,0.124,S,B,1.2,-0.37,7.444,,64.69,ABH,-1.25,0.111618,0.000561334,0.998587 beta-lactamase_2500_M67A,beta-lactamase_2500_67,TEM-1,beta-lactamase_2500,P62593,0.998589,NO,67,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-2.231,-2.183,-0.048,,0.006,G,P,0.55,-0.81,2.653,,65.03,HHP,-1.502,0.361275,0.00409753,0.998589 beta-lactamase_156_R91W,beta-lactamase_156_91,TEM-1,beta-lactamase_156,P62593,0.998596,NO,91,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.392,-5.388,3.996,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.111618,0.00380226,0.998596 beta-lactamase_39_Q267E,beta-lactamase_39_267,TEM-1,beta-lactamase_39,P62593,0.998597,NO,267,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.0495842,0.0102128,0.998597 beta-lactamase_39_I229M,beta-lactamase_39_229,TEM-1,beta-lactamase_39,P62593,0.998609,NO,229,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.267,-4.125,2.858,,0.083,E,B,0.48,-0.76,1.114,,50,HHH,-1.58767,0.0495842,0.00477249,0.998609 beta-lactamase_39_W288I,beta-lactamase_39_288,TEM-1,beta-lactamase_39,P62593,0.99861,NO,288,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,,,,,,,,,,,,,BHO,,0.0495842,,0.99861 beta-lactamase_39_H24K,beta-lactamase_39_24,TEM-1,beta-lactamase_39,P62593,0.998613,NO,24,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-2.481,-3.455,0.974,,,,,,,2.708,,93.01,OBO,-2.0035,0.0495842,0.00238894,0.998613 beta-lactamase_A182W,beta-lactamase_182,TEM-1,beta-lactamase,P62593,0.998616,NO,182,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.777,-5.53,3.753,4.98609,0.136,H,A,0.52,-0.66,2.032,,93.01,OHH,-1.27367,0.221079,0.00559099,0.998616 beta-lactamase_C75V,beta-lactamase_75,TEM-1,beta-lactamase,P62593,0.998616,NO,75,C,V,CV,Special,Hydrophobic,5.07,5.60847,0.538465,192,121,117,-4,108.5,140,31.5,-1.245,-3.383,2.138,4.88171,,H,A,0.25,-0.87,0.876,,50,HOO,-1.24333,0.221079,0.0034616,0.998616 beta-lactamase_G90M,beta-lactamase_90,TEM-1,beta-lactamase,P62593,0.998616,NO,90,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-2.091,-4.839,2.748,5.51991,0.598,T,A,0.23,0.32,1.791,,77.62,HOB,-1.52633,0.221079,0.00490273,0.998616 beta-lactamase_G90N,beta-lactamase_90,TEM-1,beta-lactamase,P62593,0.998616,NO,90,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-2.091,-2.941,0.85,5.51991,0.598,T,A,0.23,0.32,1.791,,77.62,HOB,-1.52633,0.221079,0.00490273,0.998616 beta-lactamase_H94L,beta-lactamase_94,TEM-1,beta-lactamase,P62593,0.998616,NO,94,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-2.5,-3.441,0.941,6.1507,0.776,,B,0.63,1.24,1.176,,77.62,HBH,-1.872,0.221079,0.00389226,0.998616 beta-lactamase_Q97D,beta-lactamase_97,TEM-1,beta-lactamase,P62593,0.998616,NO,97,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.072,-3.567,1.495,6.30204,0.823,G,A,1.1,2.42,1.157,,77.62,PPP,-2.43833,0.221079,0.0045116,0.998616 beta-lactamase_R159K,beta-lactamase_159,TEM-1,beta-lactamase,P62593,0.998616,NO,159,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-0.94,-2.865,1.925,5.64971,0.316,,B,0.68,-0.55,1.172,,64.34,PBH,-1.011,0.221079,0.00108472,0.998616 beta-lactamase_T267E,beta-lactamase_267,TEM-1,beta-lactamase,P62593,0.998616,NO,267,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.308,-2.44,0.132,5.28263,0.54,,B,0.69,-0.14,0.374,,73.78,HPH,-1.9,0.221079,0.0102128,0.998616 beta-lactamase_156_E61F,beta-lactamase_156_61,TEM-1,beta-lactamase_156,P62593,0.998618,NO,61,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.115,-4.422,2.307,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.111618,0.00440955,0.998618 beta-lactamase_625_M127I,beta-lactamase_625_127,TEM-1,beta-lactamase_625,P62593,0.998623,NO,127,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-2.251,-2.439,0.188,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.213352,0.00437927,0.998623 beta-lactamase_39_G253C,beta-lactamase_39_253,TEM-1,beta-lactamase_39,P62593,0.998624,NO,253,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.0495842,0.00786358,0.998624 beta-lactamase_39_E102P,beta-lactamase_39_102,TEM-1,beta-lactamase_39,P62593,0.99863,NO,102,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.118,-3.88,1.762,,0.722,S,B,1.04,1.82,3.87,,73.08,HAH,-1.581,0.0495842,0.00486633,0.99863 beta-lactamase_625_E166L,beta-lactamase_625_166,TEM-1,beta-lactamase_625,P62593,0.998631,NO,166,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.756,-2.872,1.116,,0.508,G,A,1.04,1.05,2.124,,73.08,OAH,-1.42233,0.213352,0.00512989,0.998631 kka2_1:4_T73T,kka2_1:4_73,Kka2,kka2_1:4,P00552,0.998633,NO,73,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.51,-2.51,,,0.309,H,A,0.22,0.35,1.53,,56.06,PPO,-2.02333,0.168804,0.00628605,0.998633 beta-lactamase_625_G85F,beta-lactamase_625_85,TEM-1,beta-lactamase_625,P62593,0.998634,NO,85,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.011,-4.377,3.366,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.213352,0.00252173,0.998634 kka2_1:1_S251Y,kka2_1:1_251,Kka2,kka2_1:1,P00552,0.998635,NO,251,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.636,-4.395,1.759,,0.712,H,A,0.27,-0.25,1.356,,71.59,APP,-2.09367,0.520039,0.0138916,0.998635 kka2_1:4_A166A,kka2_1:4_166,Kka2,kka2_1:4,P00552,0.99864,NO,166,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.407,-2.407,,,0.534,.,B,0.46,1.03,,,71.59,HHO,-2.421,0.168804,0.00799912,0.99864 beta-lactamase_39_Q276E,beta-lactamase_39_276,TEM-1,beta-lactamase_39,P62593,0.998645,NO,276,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.0495842,0.0191712,0.998645 beta-lactamase_39_E102V,beta-lactamase_39_102,TEM-1,beta-lactamase_39,P62593,0.99865,NO,102,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.118,-3.638,1.52,,0.722,S,B,1.04,1.82,3.87,,73.08,HAH,-1.581,0.0495842,0.00486633,0.99865 beta-lactamase_625_E169R,beta-lactamase_625_169,TEM-1,beta-lactamase_625,P62593,0.99865,NO,169,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.23,-3.638,2.408,,0.337,,A,1.04,1,1.806,,73.08,PAH,-1.16533,0.213352,0.00400994,0.99865 beta-lactamase_156_L137I,beta-lactamase_156_137,TEM-1,beta-lactamase_156,P62593,0.998654,NO,137,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.03,-2.064,1.034,,,H,A,0.55,-0.38,0.674,,42.31,HHP,-1.58933,0.111618,0.00278599,0.998654 beta-lactamase_2500_G194S,beta-lactamase_2500_194,TEM-1,beta-lactamase_2500,P62593,0.998654,NO,194,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.396,-2.171,0.775,,0.276,S,b,0.29,0.36,3.593,,67.83,POA,-1.832,0.361275,0.00392163,0.998654 beta-lactamase_2500_G39Q,beta-lactamase_2500_39,TEM-1,beta-lactamase_2500,P62593,0.998654,NO,39,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.864,-2.885,1.021,,0.701,T,L,0.29,0.47,29.926,29.926,77.62,HOH,-1.53633,0.361275,0.00487611,0.998654 beta-lactamase_2500_Q88L,beta-lactamase_2500_88,TEM-1,beta-lactamase_2500,P62593,0.998655,NO,88,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.086,-3.504,1.418,,0.807,,B,0.64,2.03,1.84,,77.62,APH,-1.53433,0.361275,0.00504167,0.998655 beta-lactamase_156_G194I,beta-lactamase_156_194,TEM-1,beta-lactamase_156,P62593,0.998656,NO,194,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.396,-4.133,2.737,,0.276,S,b,0.29,0.36,1.346,,67.83,POA,-1.832,0.111618,0.00392163,0.998656 beta-lactamase_156_S51L,beta-lactamase_156_51,TEM-1,beta-lactamase_156,P62593,0.998664,NO,51,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.526,-3.495,1.969,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.111618,0.00504821,0.998664 beta-lactamase_625_M180R,beta-lactamase_625_180,TEM-1,beta-lactamase_625,P62593,0.998664,NO,180,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-2.795,-3.843,1.048,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.213352,0.00552048,0.998664 kka2_1:2_A56A,kka2_1:2_56,Kka2,kka2_1:2,P00552,0.998666,NO,56,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.083,-2.083,,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.295029,0.00717715,0.998666 beta-lactamase_156_A200M,beta-lactamase_156_200,TEM-1,beta-lactamase_156,P62593,0.998668,NO,200,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.878,-4.732,2.854,,0.757,H,A,0.46,-0.19,16.368,16.368,77.62,HHP,-2.001,0.111618,0.0060056,0.998668 beta-lactamase_156_M127S,beta-lactamase_156_127,TEM-1,beta-lactamase_156,P62593,0.99867,NO,127,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-2.251,-3.644,1.393,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.111618,0.00437927,0.99867 kka2_1:2_D154G,kka2_1:2_154,Kka2,kka2_1:2,P00552,0.99867,NO,154,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.876,-3.201,2.325,,0.457,,b,0.29,1.48,3.631,,52.65,HAP,-1.52467,0.295029,0.00292633,0.99867 Pab1_I183K,Pab1_183,Pab1,Pab1,P04147,0.99867,NO,183,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.302,-3.717,2.415,,0.308,T,B,1,1.08,1.29,,75.56,HHA,-1.27167,0.175299,0.000574345,0.99867 kka2_1:4_Q163Q,kka2_1:4_163,Kka2,kka2_1:4,P00552,0.998673,NO,163,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.162,-2.162,,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.168804,0.00719507,0.998673 kka2_1:2_L158L,kka2_1:2_158,Kka2,kka2_1:2,P00552,0.998676,NO,158,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.947,-1.947,,,0.095,,B,1.59,0.77,7.588,,63.64,AHA,-1.25333,0.295029,0.00529068,0.998676 kka2_1:8_S251S,kka2_1:8_251,Kka2,kka2_1:8,P00552,0.998683,NO,251,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.636,-2.636,,,0.712,H,A,0.27,-0.25,,,71.59,APP,-2.09367,0.100394,0.0138916,0.998683 kka2_1:8_S251S,kka2_1:8_251,Kka2,kka2_1:8,P00552,0.998683,NO,251,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.636,-2.636,,,0.712,H,A,0.27,-0.25,,,71.59,APP,-2.09367,0.100394,0.0138916,0.998683 beta-lactamase_2500_A200T,beta-lactamase_2500_200,TEM-1,beta-lactamase_2500,P62593,0.998684,NO,200,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.878,-2.493,0.615,,0.757,H,A,0.46,-0.19,0.436,,77.62,HHP,-2.001,0.361275,0.0060056,0.998684 beta-lactamase_625_T147R,beta-lactamase_625_147,TEM-1,beta-lactamase_625,P62593,0.998686,NO,147,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.149,-3.809,2.66,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.213352,0.00226017,0.998686 beta-lactamase_625_G39T,beta-lactamase_625_39,TEM-1,beta-lactamase_625,P62593,0.998691,NO,39,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.864,-2.931,1.067,,0.701,T,L,0.29,0.47,29.926,29.926,77.62,HOH,-1.53633,0.213352,0.00487611,0.998691 beta-lactamase_156_N173G,beta-lactamase_156_173,TEM-1,beta-lactamase_156,P62593,0.998692,NO,173,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-2.663,-1.002,-1.661,,1.044,T,l,0.61,1.25,3.718,,77.62,OPA,-1.46633,0.111618,0.0033769,0.998692 beta-lactamase_39_A84L,beta-lactamase_39_84,TEM-1,beta-lactamase_39,P62593,0.998692,NO,84,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.651,-3.508,1.857,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.0495842,0.00503822,0.998692 kka2_1:8_A79A,kka2_1:8_79,Kka2,kka2_1:8,P00552,0.9987,NO,79,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.368,-2.368,,,0.563,.,B,0.46,-0.43,,,71.59,HHH,-1.752,0.100394,0.00664821,0.9987 kka2_1:8_A79A,kka2_1:8_79,Kka2,kka2_1:8,P00552,0.9987,NO,79,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.368,-2.368,,,0.563,.,B,0.46,-0.43,,,71.59,HHH,-1.752,0.100394,0.00664821,0.9987 beta-lactamase_0_F149P,beta-lactamase_0_149,TEM-1,beta-lactamase_0,P62593,0.998701,NO,149,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.299,-4.282,2.983,,0.195,H,A,0.58,0.11,3.518,,63.99,HHH,-1.46067,0.0500837,0.00418462,0.998701 kka2_1:4_L53L,kka2_1:4_53,Kka2,kka2_1:4,P00552,0.998705,NO,53,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-2.681,-2.681,,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.168804,0.00671168,0.998705 kka2_1:4_V46V,kka2_1:4_46,Kka2,kka2_1:4,P00552,0.998705,NO,46,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-2.62,-2.62,,,0.192,.,B,0.44,-1.12,9.564,,92.05,OHH,-1.88633,0.168804,0.00631301,0.998705 beta-lactamase_156_I229Y,beta-lactamase_156_229,TEM-1,beta-lactamase_156,P62593,0.998708,NO,229,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.267,-4.04,2.773,,0.083,E,B,0.48,-0.76,1.114,,50,HHH,-1.58767,0.111618,0.00477249,0.998708 kka2_1:2_E230E,kka2_1:2_230,Kka2,kka2_1:2,P00552,0.998708,NO,230,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.672,-2.672,,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.295029,0.00920051,0.998708 beta-lactamase_L223V,beta-lactamase_223,TEM-1,beta-lactamase,P62593,0.998711,NO,223,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.055,-2.195,1.14,5.42318,0.27,,B,1.3,0.09,1.511,,74.48,HHO,-1.35033,0.221079,0.00372793,0.998711 beta-lactamase_39_A182F,beta-lactamase_39_182,TEM-1,beta-lactamase_39,P62593,0.998712,NO,182,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.777,-4.357,2.58,,0.136,H,A,0.46,-0.66,2.598,,93.01,OHH,-1.27367,0.0495842,0.00559099,0.998712 beta-lactamase_156_A77K,beta-lactamase_156_77,TEM-1,beta-lactamase_156,P62593,0.998714,NO,77,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.234,-3.628,2.394,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.111618,0.00282362,0.998714 kka2_1:4_D23D,kka2_1:4_23,Kka2,kka2_1:4,P00552,0.998716,NO,23,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.459,-2.459,,,0.695,E,B,0.75,-0.65,2.416,,65.53,HAH,-1.94033,0.168804,0.007195,0.998716 kka2_1:1_S114S,kka2_1:1_114,Kka2,kka2_1:1,P00552,0.998719,NO,114,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.527,-2.527,,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.520039,0.00705262,0.998719 kka2_1:4_E160E,kka2_1:4_160,Kka2,kka2_1:4,P00552,0.998719,NO,160,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.683,-1.683,,,0.989,G,A,1.04,2.28,2.531,,71.59,AAA,-1.36133,0.168804,0.00935762,0.998719 beta-lactamase_P172D,beta-lactamase_172,TEM-1,beta-lactamase,P62593,0.998721,NO,172,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.998,-3.578,2.58,5.98941,0.639,T,b,1.1,0.24,2.087,,74.48,HOP,-2.03067,0.221079,0.00312594,0.998721 beta-lactamase_625_A268R,beta-lactamase_625_268,TEM-1,beta-lactamase_625,P62593,0.998722,NO,268,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.213352,0.0102525,0.998722 beta-lactamase_0_N50D,beta-lactamase_0_50,TEM-1,beta-lactamase_0,P62593,0.998723,NO,50,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-2.979,-2.468,-0.511,,0.912,T,A,0.61,1.24,9.874,9.874,77.62,HPP,-2.134,0.0500837,0.0047211,0.998723 beta-lactamase_625_G154D,beta-lactamase_625_154,TEM-1,beta-lactamase_625,P62593,0.998724,NO,154,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.823,-2.317,1.494,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.213352,0.00180205,0.998724 beta-lactamase_39_T107S,beta-lactamase_39_107,TEM-1,beta-lactamase_39,P62593,0.998727,NO,107,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.117,-1.871,0.754,,,G,A,0.22,-0.06,2.686,,67.83,HPA,-1.265,0.0495842,0.00239347,0.998727 beta-lactamase_39_G194M,beta-lactamase_39_194,TEM-1,beta-lactamase_39,P62593,0.998728,NO,194,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.396,-4.893,3.497,,0.276,S,b,0.29,0.36,4.852,,67.83,POA,-1.832,0.0495842,0.00392163,0.998728 beta-lactamase_39_H24A,beta-lactamase_39_24,TEM-1,beta-lactamase_39,P62593,0.998728,NO,24,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-2.481,-2.265,-0.216,,,,,,,2.708,,93.01,OBO,-2.0035,0.0495842,0.00238894,0.998728 beta-lactamase_39_L223F,beta-lactamase_39_223,TEM-1,beta-lactamase_39,P62593,0.998729,NO,223,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.055,-2.724,1.669,,0.27,,B,0.55,0.09,1.511,,74.48,HHO,-1.35033,0.0495842,0.00372793,0.998729 beta-lactamase_156_D36H,beta-lactamase_156_36,TEM-1,beta-lactamase_156,P62593,0.99873,NO,36,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.732,-3.09,0.358,,0.555,H,A,0.75,1.17,14.871,14.871,77.62,AAP,-1.91167,0.111618,0.00476483,0.99873 beta-lactamase_A211G,beta-lactamase_211,TEM-1,beta-lactamase,P62593,0.998734,NO,211,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.896,-2.355,0.459,5.54662,0.369,T,A,0.52,-0.69,2.061,,77.62,AHA,-1.94633,0.221079,0.00648183,0.998734 kka2_1:4_A35A,kka2_1:4_35,Kka2,kka2_1:4,P00552,0.998734,NO,35,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.127,-2.127,,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.168804,0.00630016,0.998734 beta-lactamase_156_M66C,beta-lactamase_156_66,TEM-1,beta-lactamase_156,P62593,0.998735,NO,66,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.362,-4.734,3.372,,0.013,,A,0.55,-0.7,1.94,,73.08,OHH,-1.49567,0.111618,0.00412876,0.998735 beta-lactamase_625_E169L,beta-lactamase_625_169,TEM-1,beta-lactamase_625,P62593,0.998738,NO,169,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.23,-3.533,2.303,,0.337,,A,1.04,1,1.806,,73.08,PAH,-1.16533,0.213352,0.00400994,0.998738 beta-lactamase_625_S241A,beta-lactamase_625_241,TEM-1,beta-lactamase_625,P62593,0.99874,NO,241,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.213352,0.00452736,0.99874 beta-lactamase_625_S80C,beta-lactamase_625_80,TEM-1,beta-lactamase_625,P62593,0.99874,NO,80,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.029,-4.922,2.893,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.213352,0.00565569,0.99874 beta-lactamase_625_W163S,beta-lactamase_625_163,TEM-1,beta-lactamase_625,P62593,0.99874,NO,163,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-1.843,-3.614,1.771,,0.467,,B,0.47,-0.5,5.019,,63.99,BHA,-1.269,0.213352,0.00418955,0.99874 beta-lactamase_156_G43S,beta-lactamase_156_43,TEM-1,beta-lactamase_156,P62593,0.998741,NO,43,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.62,-3.161,2.541,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.111618,0.00120151,0.998741 beta-lactamase_625_G39R,beta-lactamase_625_39,TEM-1,beta-lactamase_625,P62593,0.998741,NO,39,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.864,-3.077,1.213,,0.701,T,L,0.29,0.47,29.926,29.926,77.62,HOH,-1.53633,0.213352,0.00487611,0.998741 beta-lactamase_39_G90H,beta-lactamase_39_90,TEM-1,beta-lactamase_39,P62593,0.998742,NO,90,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-2.091,-3.353,1.262,,0.598,T,A,0.29,0.32,30.794,30.794,77.62,HOB,-1.52633,0.0495842,0.00490273,0.998742 beta-lactamase_156_G141I,beta-lactamase_156_141,TEM-1,beta-lactamase_156,P62593,0.998743,NO,141,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.828,-4.236,3.408,,0.575,T,l,0.29,-0.28,0.198,,64.69,HOO,-1.08933,0.111618,0.0012419,0.998743 kka2_1:4_G43G,kka2_1:4_43,Kka2,kka2_1:4,P00552,0.998744,NO,43,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.587,-1.587,,,0.862,T,l,0.75,-0.67,2.247,,63.26,POB,-2.18533,0.168804,0.0071925,0.998744 beta-lactamase_39_D83E,beta-lactamase_39_83,TEM-1,beta-lactamase_39,P62593,0.998745,NO,83,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.066,-2.025,0.959,,0.354,H,A,0.75,0.22,0.752,,48.95,HAH,-1.34733,0.0495842,0.00205968,0.998745 beta-lactamase_625_M67L,beta-lactamase_625_67,TEM-1,beta-lactamase_625,P62593,0.998746,NO,67,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-2.231,-2.657,0.426,,0.006,G,P,0.55,-0.81,2.653,,65.03,HHP,-1.502,0.213352,0.00409753,0.998746 kka2_1:4_H8H,kka2_1:4_8,Kka2,kka2_1:4,P00552,0.998748,NO,8,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-2.759,-2.759,,,,,,,,,,71.59,HBH,-2.25467,0.168804,0.00256422,0.998748 kka2_1:4_L165L,kka2_1:4_165,Kka2,kka2_1:4,P00552,0.998748,NO,165,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-2.453,-2.453,,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.168804,0.00801161,0.998748 beta-lactamase_39_A182T,beta-lactamase_39_182,TEM-1,beta-lactamase_39,P62593,0.99875,NO,182,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.777,-2.685,0.908,,0.136,H,A,0.46,-0.66,2.598,,93.01,OHH,-1.27367,0.0495842,0.00559099,0.99875 beta-lactamase_156_D207C,beta-lactamase_156_207,TEM-1,beta-lactamase_156,P62593,0.998751,NO,207,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.064,-5.19,3.126,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.111618,0.00592942,0.998751 beta-lactamase_625_L73T,beta-lactamase_625_73,TEM-1,beta-lactamase_625,P62593,0.998753,NO,73,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.507,-3.582,2.075,,,H,A,0.55,-0.64,2.933,,67.83,HHH,-1.487,0.213352,0.00488983,0.998753 beta-lactamase_625_Q37C,beta-lactamase_625_37,TEM-1,beta-lactamase_625,P62593,0.998753,NO,37,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.134,-5.133,2.999,,0.613,H,A,0.64,1.98,1.318,,73.08,APH,-2.06967,0.213352,0.00425833,0.998753 kka2_1:1_Q163Q,kka2_1:1_163,Kka2,kka2_1:1,P00552,0.998753,NO,163,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.162,-2.162,,,0.58,T,B,0.64,1.85,2.779,,64.02,BPO,-1.78333,0.520039,0.00719507,0.998753 kka2_1:1_V16V,kka2_1:1_16,Kka2,kka2_1:1,P00552,0.998753,NO,16,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-3.087,-3.087,,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.520039,0.00694011,0.998753 beta-lactamase_625_P217A,beta-lactamase_625_217,TEM-1,beta-lactamase_625,P62593,0.998755,NO,217,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-2.062,-1.891,-0.171,,0.496,I,A,0.52,-0.33,1.087,,74.48,OOH,-1.64333,0.213352,0.00463211,0.998755 beta-lactamase_2500_L199G,beta-lactamase_2500_199,TEM-1,beta-lactamase_2500,P62593,0.998757,NO,199,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-2.942,-2.663,-0.279,,0.832,H,A,0.55,0.42,15.504,15.504,77.62,PHH,-2.32933,0.361275,0.0048649,0.998757 beta-lactamase_39_Y95H,beta-lactamase_39_95,TEM-1,beta-lactamase_39,P62593,0.99876,NO,95,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-1.715,-3.182,1.467,,0.122,,b,0.21,-0.37,2.341,,77.62,BHP,-2.16167,0.0495842,0.00479449,0.99876 beta-lactamase_39_A148C,beta-lactamase_39_148,TEM-1,beta-lactamase_39,P62593,0.998761,NO,148,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.757,-5.042,3.285,,0.379,H,A,0.46,-0.55,3.551,,72.73,PHH,-1.40167,0.0495842,0.00547053,0.998761 beta-lactamase_C18C,beta-lactamase_18,TEM-1,beta-lactamase,P62593,0.998761,NO,18,C,C,CC,Special,Special,5.07,5.07,0,0,121,121,0,108.5,108.5,0,-2.26,-2.26,,,,,,,,3.995,,93.01,HOH,-2.093,0.221079,0.002536,0.998761 beta-lactamase_2500_A182C,beta-lactamase_2500_182,TEM-1,beta-lactamase_2500,P62593,0.998762,NO,182,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.777,-5.025,3.248,,0.136,H,A,0.46,-0.66,2.032,,93.01,OHH,-1.27367,0.361275,0.00559099,0.998762 beta-lactamase_156_W208D,beta-lactamase_156_208,TEM-1,beta-lactamase_156,P62593,0.998767,NO,208,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-0.818,-4.144,3.326,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.111618,0.00126609,0.998767 beta-lactamase_625_V72P,beta-lactamase_625_72,TEM-1,beta-lactamase_625,P62593,0.998768,NO,72,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.658,-2.442,0.784,,,H,A,0.44,-1.03,0.981,,65.73,BHH,-1.32167,0.213352,0.00501194,0.998768 beta-lactamase_156_L28I,beta-lactamase_156_28,TEM-1,beta-lactamase_156,P62593,0.99877,NO,28,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.579,-2.204,0.625,,0.277,H,A,0.55,-0.16,3.262,,93.01,PHH,-2.11333,0.111618,0.00359321,0.99877 beta-lactamase_39_N98D,beta-lactamase_39_98,TEM-1,beta-lactamase_39,P62593,0.998771,NO,98,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-2.973,-2.35,-0.623,,0.963,G,A,0.61,1.35,14.853,14.853,77.62,PPA,-2.07867,0.0495842,0.00505389,0.998771 beta-lactamase_S57M,beta-lactamase_57,TEM-1,beta-lactamase,P62593,0.998771,NO,57,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.918,-4.684,2.766,5.64201,0.352,E,B,0.25,-0.18,1.971,,72.73,APH,-2.29167,0.221079,0.00492804,0.998771 beta-lactamase_S96E,beta-lactamase_96,TEM-1,beta-lactamase,P62593,0.998771,NO,96,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.27,-2.567,0.297,5.29889,0.368,,b,0.25,0.39,32.348,32.348,73.78,HPP,-2.019,0.221079,0.00551835,0.998771 beta-lactamase_625_L137T,beta-lactamase_625_137,TEM-1,beta-lactamase_625,P62593,0.998773,NO,137,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.03,-3.486,2.456,,,H,A,0.55,-0.38,1.5,,42.31,HHP,-1.58933,0.213352,0.00278599,0.998773 kka2_1:4_A14A,kka2_1:4_14,Kka2,kka2_1:4,P00552,0.998773,NO,14,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.837,-1.837,,,0.728,G,A,0.46,0.7,0.36,,71.59,HHH,-1.82567,0.168804,0.00706614,0.998773 kka2_1:2_A137A,kka2_1:2_137,Kka2,kka2_1:2,P00552,0.998774,NO,137,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.156,-2.156,,,0.029,H,A,0.46,0.34,1.323,,63.26,PHB,-2.559,0.295029,0.00515054,0.998774 beta-lactamase_R238Y,beta-lactamase_238,TEM-1,beta-lactamase,P62593,0.998776,NO,238,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.002,-2.147,0.145,5.87663,0.564,T,L,0.45,1.09,4.195,,72.73,ABO,-1.62633,0.221079,0.00743256,0.998776 beta-lactamase_2500_N173W,beta-lactamase_2500_173,TEM-1,beta-lactamase_2500,P62593,0.998778,NO,173,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-2.663,-5.303,2.64,,1.044,T,l,0.61,1.25,1.88,,77.62,OPA,-1.46633,0.361275,0.0033769,0.998778 beta-lactamase_625_A225V,beta-lactamase_625_225,TEM-1,beta-lactamase_625,P62593,0.998778,NO,225,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.845,-3.655,1.81,,1,T,B,0.46,-0.38,9.874,9.874,74.48,OHO,-1.39967,0.213352,0.00465057,0.998778 beta-lactamase_625_A182R,beta-lactamase_625_182,TEM-1,beta-lactamase_625,P62593,0.99878,NO,182,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.777,-2.31,0.533,,0.136,H,A,0.46,-0.66,16.784,16.784,93.01,OHH,-1.27367,0.213352,0.00559099,0.99878 kka2_1:4_A25A,kka2_1:4_25,Kka2,kka2_1:4,P00552,0.99878,NO,25,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.496,-2.496,,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.168804,0.00595636,0.99878 kka2_1:8_S11S,kka2_1:8_11,Kka2,kka2_1:8,P00552,0.998782,NO,11,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.322,-2.322,,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.100394,0.00381691,0.998782 kka2_1:8_S11S,kka2_1:8_11,Kka2,kka2_1:8,P00552,0.998782,NO,11,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.322,-2.322,,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.100394,0.00381691,0.998782 beta-lactamase_156_P172H,beta-lactamase_156_172,TEM-1,beta-lactamase_156,P62593,0.998784,NO,172,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.998,-4.746,3.748,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.111618,0.00312594,0.998784 beta-lactamase_E166E,beta-lactamase_166,TEM-1,beta-lactamase,P62593,0.998785,NO,166,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.756,-1.756,,5.60527,0.508,G,A,0.52,1.05,2.124,,73.08,OAH,-1.42233,0.221079,0.00512989,0.998785 beta-lactamase_F22L,beta-lactamase_22,TEM-1,beta-lactamase,P62593,0.998785,NO,22,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-2.676,-2.266,-0.41,,,,,,,1.616,,73.08,HHH,-2.03233,0.221079,0.00262842,0.998785 beta-lactamase_156_D36N,beta-lactamase_156_36,TEM-1,beta-lactamase_156,P62593,0.998787,NO,36,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.732,-3.002,0.27,,0.555,H,A,0.75,1.17,14.871,14.871,77.62,AAP,-1.91167,0.111618,0.00476483,0.998787 beta-lactamase_39_I125M,beta-lactamase_39_125,TEM-1,beta-lactamase_39,P62593,0.998787,NO,125,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.441,-2.597,1.156,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.0495842,0.00383964,0.998787 beta-lactamase_625_R41P,beta-lactamase_625_41,TEM-1,beta-lactamase_625,P62593,0.998787,NO,41,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-0.942,-3.877,2.935,,0.321,E,B,1.2,-0.07,1.186,,65.03,HBH,-1.30267,0.213352,0.00123327,0.998787 beta-lactamase_625_P165H,beta-lactamase_625_165,TEM-1,beta-lactamase_625,P62593,0.998789,NO,165,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.373,-4.751,3.378,,0.203,T,A,0.52,-0.31,0.414,,73.78,AOA,-1.359,0.213352,0.00549538,0.998789 beta-lactamase_156_L100C,beta-lactamase_156_100,TEM-1,beta-lactamase_156,P62593,0.998791,NO,100,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.218,-4.758,3.54,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.111618,0.00413885,0.998791 beta-lactamase_39_A123K,beta-lactamase_39_123,TEM-1,beta-lactamase_39,P62593,0.998793,NO,123,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.834,-3.506,2.672,,0.039,H,A,0.46,-0.72,0.705,,41.26,PHH,-1.47367,0.0495842,0.0010157,0.998793 beta-lactamase_39_E145W,beta-lactamase_39_145,TEM-1,beta-lactamase_39,P62593,0.998793,NO,145,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.357,-5.352,2.995,,0.545,H,A,1.04,0.79,1.199,,77.62,BAH,-2.069,0.0495842,0.00553285,0.998793 beta-lactamase_156_G253A,beta-lactamase_156_253,TEM-1,beta-lactamase_156,P62593,0.998794,NO,253,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.111618,0.00786358,0.998794 beta-lactamase_39_M270Y,beta-lactamase_39_270,TEM-1,beta-lactamase_39,P62593,0.998797,NO,270,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.0495842,0.00767762,0.998797 beta-lactamase_39_S266R,beta-lactamase_39_266,TEM-1,beta-lactamase_39,P62593,0.998798,NO,266,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.0495842,0.0140785,0.998798 beta-lactamase_39_K30Q,beta-lactamase_39_30,TEM-1,beta-lactamase_39,P62593,0.998799,NO,30,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-2.307,-2.158,-0.149,,0.142,H,A,2.34,-0.65,6.717,,93.01,HBH,-2.32833,0.0495842,0.00448593,0.998799 beta-lactamase_625_V78I,beta-lactamase_625_78,TEM-1,beta-lactamase_625,P62593,0.9988,NO,78,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.459,-1.96,0.501,,,H,A,0.44,-0.47,2.045,,63.64,HHH,-1.17833,0.213352,0.00492501,0.9988 beta-lactamase_156_G142A,beta-lactamase_156_142,TEM-1,beta-lactamase_156,P62593,0.998804,NO,142,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.707,-2.85,2.143,,0.034,,p,0.29,-0.64,0.325,,64.69,OOO,-0.834,0.111618,0.00060149,0.998804 PSD95pdz3_E352F,PSD95pdz3_352,PSD95pdz3,PSD95pdz3,P31016,0.998808,NO,352,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.587,-3.973,2.386,5.49659,,,,,24.2,2.525,,86.88,OAH,-1.314,0.0758425,0.000892231,0.998808 beta-lactamase_625_T193D,beta-lactamase_625_193,TEM-1,beta-lactamase_625,P62593,0.998809,NO,193,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.914,-3.815,1.901,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.213352,0.00482669,0.998809 beta-lactamase_2500_L196W,beta-lactamase_2500_196,TEM-1,beta-lactamase_2500,P62593,0.99881,NO,196,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-2.478,-5.492,3.014,,0.518,S,A,0.55,1.35,7.897,,77.62,AHH,-1.839,0.361275,0.00512144,0.99881 beta-lactamase_39_A215G,beta-lactamase_39_215,TEM-1,beta-lactamase_39,P62593,0.998811,NO,215,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.503,-1.579,0.076,,,,a,0.46,-0.93,0.494,,74.48,HHO,-1.42633,0.0495842,0.00544007,0.998811 beta-lactamase_625_V72T,beta-lactamase_625_72,TEM-1,beta-lactamase_625,P62593,0.998811,NO,72,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.658,-2.757,1.099,,,H,A,0.44,-1.03,0.981,,65.73,BHH,-1.32167,0.213352,0.00501194,0.998811 beta-lactamase_625_D207M,beta-lactamase_625_207,TEM-1,beta-lactamase_625,P62593,0.998813,NO,207,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.064,-4.822,2.758,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.213352,0.00592942,0.998813 kka2_1:4_A9A,kka2_1:4_9,Kka2,kka2_1:4,P00552,0.998813,NO,9,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.079,-2.079,,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.168804,0.00273264,0.998813 beta-lactamase_39_G85V,beta-lactamase_39_85,TEM-1,beta-lactamase_39,P62593,0.998814,NO,85,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.011,-3.796,2.785,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.0495842,0.00252173,0.998814 beta-lactamase_39_M127H,beta-lactamase_39_127,TEM-1,beta-lactamase_39,P62593,0.998815,NO,127,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-2.251,-4.786,2.535,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.0495842,0.00437927,0.998815 beta-lactamase_156_V82E,beta-lactamase_156_82,TEM-1,beta-lactamase_156,P62593,0.998818,NO,82,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.325,-3.751,2.426,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.111618,0.00397046,0.998818 PSD95pdz3_R368W,PSD95pdz3_368,PSD95pdz3,PSD95pdz3,P31016,0.998818,NO,368,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.582,-5.004,3.422,6.13355,,,,,18.1818,,,,HBP,-1.50033,0.0758425,0.000451517,0.998818 kka2_1:2_G181G,kka2_1:2_181,Kka2,kka2_1:2,P00552,0.998821,NO,181,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-2.698,-2.698,,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.295029,0.00728319,0.998821 beta-lactamase_625_R189G,beta-lactamase_625_189,TEM-1,beta-lactamase_625,P62593,0.998829,NO,189,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.844,-3.504,1.66,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.213352,0.0050699,0.998829 beta-lactamase_625_S241Q,beta-lactamase_625_241,TEM-1,beta-lactamase_625,P62593,0.998834,NO,241,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.213352,0.00452736,0.998834 kka2_1:2_S40S,kka2_1:2_40,Kka2,kka2_1:2,P00552,0.99884,NO,40,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.645,-2.645,,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.295029,0.00693477,0.99884 beta-lactamase_156_Q267A,beta-lactamase_156_267,TEM-1,beta-lactamase_156,P62593,0.998841,NO,267,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.111618,0.0102128,0.998841 beta-lactamase_625_G281A,beta-lactamase_625_281,TEM-1,beta-lactamase_625,P62593,0.998841,NO,281,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.213352,0.0406482,0.998841 kka2_1:2_T130T,kka2_1:2_130,Kka2,kka2_1:2,P00552,0.998843,NO,130,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.392,-2.392,,,0.561,G,A,0.22,0.77,0.5,,92.05,HPO,-1.62633,0.295029,0.00804204,0.998843 beta-lactamase_625_A77L,beta-lactamase_625_77,TEM-1,beta-lactamase_625,P62593,0.998847,NO,77,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.234,-2.423,1.189,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.213352,0.00282362,0.998847 beta-lactamase_625_R162A,beta-lactamase_625_162,TEM-1,beta-lactamase_625,P62593,0.998847,NO,162,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.016,-3.127,2.111,,0.124,S,B,1.2,-0.37,1.445,,64.69,ABH,-1.25,0.213352,0.000561334,0.998847 kka2_1:1_E149E,kka2_1:1_149,Kka2,kka2_1:1,P00552,0.998848,NO,149,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.994,-1.994,,,0.674,H,A,1.04,1.63,3.671,,71.59,HAH,-1.59667,0.520039,0.00803343,0.998848 beta-lactamase_156_C75V,beta-lactamase_156_75,TEM-1,beta-lactamase_156,P62593,0.998849,NO,75,C,V,CV,Special,Hydrophobic,5.07,5.60847,0.538465,192,121,117,-4,108.5,140,31.5,-1.245,-3.383,2.138,,,H,A,0.46,-0.87,0.876,,50,HOO,-1.24333,0.111618,0.0034616,0.998849 beta-lactamase_156_T116M,beta-lactamase_156_116,TEM-1,beta-lactamase_156,P62593,0.99885,NO,116,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.28,-4.634,3.354,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.111618,0.00336175,0.99885 beta-lactamase_625_A133C,beta-lactamase_625_133,TEM-1,beta-lactamase_625,P62593,0.998852,NO,133,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.186,-4.706,3.52,,,H,A,0.46,-0.86,0.373,,67.83,HHP,-0.988333,0.213352,0.00468022,0.998852 beta-lactamase_156_M127I,beta-lactamase_156_127,TEM-1,beta-lactamase_156,P62593,0.998854,NO,127,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-2.251,-2.439,0.188,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.111618,0.00437927,0.998854 beta-lactamase_156_L197T,beta-lactamase_156_197,TEM-1,beta-lactamase_156,P62593,0.998855,NO,197,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.853,-3.419,2.566,,0.007,S,B,0.55,0.33,1.58,,60.14,HHP,-1.833,0.111618,0.00144602,0.998855 beta-lactamase_2500_K32M,beta-lactamase_2500_32,TEM-1,beta-lactamase_2500,P62593,0.998855,NO,32,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.984,-4.613,2.629,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.361275,0.00401283,0.998855 beta-lactamase_Q265R,beta-lactamase_265,TEM-1,beta-lactamase,P62593,0.998855,NO,265,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.58,-2.897,0.317,6.62674,1.116,,A,0.03,1.17,12.514,12.514,69.58,PPH,-1.978,0.221079,0.00811926,0.998855 kka2_1:1_L53L,kka2_1:1_53,Kka2,kka2_1:1,P00552,0.998856,NO,53,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-2.681,-2.681,,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.520039,0.00671168,0.998856 beta-lactamase_156_E46W,beta-lactamase_156_46,TEM-1,beta-lactamase_156,P62593,0.998857,NO,46,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.94,-5.418,3.478,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.111618,0.00427568,0.998857 beta-lactamase_625_P250N,beta-lactamase_625_250,TEM-1,beta-lactamase_625,P62593,0.998858,NO,250,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.213352,0.00550899,0.998858 kka2_1:2_Q61Q,kka2_1:2_61,Kka2,kka2_1:2,P00552,0.998859,NO,61,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.982,-2.982,,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.295029,0.00612092,0.998859 kka2_1:4_V83V,kka2_1:4_83,Kka2,kka2_1:4,P00552,0.998859,NO,83,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-2.567,-2.567,,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.168804,0.00650486,0.998859 Pab1_N162V,Pab1_162,Pab1,Pab1,P04147,0.998859,NO,162,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-2.313,-3.403,1.09,,0.681,T,A,,1.12,,,,APO,-1.532,0.175299,0.0030719,0.998859 beta-lactamase_39_Q88P,beta-lactamase_39_88,TEM-1,beta-lactamase_39,P62593,0.998861,NO,88,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.086,-3.948,1.862,,0.807,,B,0.64,2.03,11.108,11.108,77.62,APH,-1.53433,0.0495842,0.00504167,0.998861 kka2_1:2_A41A,kka2_1:2_41,Kka2,kka2_1:2,P00552,0.998862,NO,41,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.879,-1.879,,,0.184,.,B,0.46,-0.96,24.451,24.451,64.39,PHP,-2.477,0.295029,0.00543332,0.998862 beta-lactamase_39_I54V,beta-lactamase_39_54,TEM-1,beta-lactamase_39,P62593,0.998863,NO,54,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-2.838,-2.687,-0.151,,0.669,E,B,0.48,-0.14,1.349,,73.78,BHH,-2.337,0.0495842,0.00403589,0.998863 beta-lactamase_0_N50F,beta-lactamase_0_50,TEM-1,beta-lactamase_0,P62593,0.998868,NO,50,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-2.979,-4.333,1.354,,0.912,T,A,0.61,1.24,9.874,9.874,77.62,HPP,-2.134,0.0500837,0.0047211,0.998868 gb1_V247K,gb1_247,gb1,gb1,P06654,0.99887,NO,247,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.711,-3.504,1.793,,,,,,,0.805,,44.87,HHA,-1.485,0.177985,0.00435373,0.99887 beta-lactamase_156_V214R,beta-lactamase_156_214,TEM-1,beta-lactamase_156,P62593,0.998873,NO,214,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.299,-4.047,2.748,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.111618,0.00628442,0.998873 beta-lactamase_156_L219R,beta-lactamase_156_219,TEM-1,beta-lactamase_156,P62593,0.998875,NO,219,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.313,-4.126,2.813,,,I,A,0.55,-0.51,2.321,,74.48,HHB,-1.21533,0.111618,0.00664345,0.998875 beta-lactamase_625_T269S,beta-lactamase_625_269,TEM-1,beta-lactamase_625,P62593,0.998875,NO,269,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.213352,0.00950944,0.998875 beta-lactamase_156_P181G,beta-lactamase_156_181,TEM-1,beta-lactamase_156,P62593,0.998877,NO,181,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.813,-3.321,2.508,,,H,A,0.52,-1.14,1.078,,61.54,HOH,-1.795,0.111618,0.000703122,0.998877 kka2_1:4_P249P,kka2_1:4_249,Kka2,kka2_1:4,P00552,0.998877,NO,249,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.867,-1.867,,,0.406,.,B,0.52,-0.01,,,92.05,HOA,-1.66867,0.168804,0.011045,0.998877 beta-lactamase_625_L28I,beta-lactamase_625_28,TEM-1,beta-lactamase_625,P62593,0.998881,NO,28,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.579,-2.204,0.625,,0.277,H,A,0.55,-0.16,2.716,,93.01,PHH,-2.11333,0.213352,0.00359321,0.998881 kka2_1:2_H139H,kka2_1:2_139,Kka2,kka2_1:2,P00552,0.998881,NO,139,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-2.809,-2.809,,,0.471,H,A,0.87,0.68,13.912,13.912,63.64,BBB,-2.22,0.295029,0.00734779,0.998881 kka2_1:8_T73T,kka2_1:8_73,Kka2,kka2_1:8,P00552,0.998881,NO,73,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.51,-2.51,,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.100394,0.00628605,0.998881 kka2_1:8_T73T,kka2_1:8_73,Kka2,kka2_1:8,P00552,0.998881,NO,73,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.51,-2.51,,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.100394,0.00628605,0.998881 beta-lactamase_156_F58M,beta-lactamase_156_58,TEM-1,beta-lactamase_156,P62593,0.998882,NO,58,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-2.914,-4.667,1.753,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.111618,0.00523369,0.998882 beta-lactamase_156_I125T,beta-lactamase_156_125,TEM-1,beta-lactamase_156,P62593,0.998885,NO,125,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.441,-2.752,1.311,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.111618,0.00383964,0.998885 beta-lactamase_39_S283G,beta-lactamase_39_283,TEM-1,beta-lactamase_39,P62593,0.998886,NO,283,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.0495842,0.0429138,0.998886 beta-lactamase_39_K53F,beta-lactamase_39_53,TEM-1,beta-lactamase_39,P62593,0.998888,NO,53,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-2.313,-4.249,1.936,,0.589,,B,2.34,1.15,15.633,15.633,77.62,OBH,-2.1,0.0495842,0.00383383,0.998888 beta-lactamase_625_G194E,beta-lactamase_625_194,TEM-1,beta-lactamase_625,P62593,0.998898,NO,194,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.396,-2.361,0.965,,0.276,S,b,0.29,0.36,3.593,,67.83,POA,-1.832,0.213352,0.00392163,0.998898 beta-lactamase_625_W163H,beta-lactamase_625_163,TEM-1,beta-lactamase_625,P62593,0.998899,NO,163,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-1.843,-3.378,1.535,,0.467,,B,0.47,-0.5,5.019,,63.99,BHA,-1.269,0.213352,0.00418955,0.998899 kka2_1:4_H139H,kka2_1:4_139,Kka2,kka2_1:4,P00552,0.998899,NO,139,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-2.809,-2.809,,,0.471,H,A,0.17,0.68,12.761,12.761,63.64,BBB,-2.22,0.168804,0.00734779,0.998899 kka2_1:4_T130T,kka2_1:4_130,Kka2,kka2_1:4,P00552,0.998899,NO,130,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.392,-2.392,,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.168804,0.00804204,0.998899 beta-lactamase_0_G234C,beta-lactamase_0_234,TEM-1,beta-lactamase_0,P62593,0.998904,NO,234,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.62,-5.087,4.467,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.0500837,0.000889577,0.998904 beta-lactamase_2500_P60A,beta-lactamase_2500_60,TEM-1,beta-lactamase_2500,P62593,0.998908,NO,60,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-2.469,-1.436,-1.033,,0.256,T,A,0.52,-0.56,1.581,,77.62,BOA,-1.97633,0.361275,0.00521318,0.998908 kka2_1:1_A65A,kka2_1:1_65,Kka2,kka2_1:1,P00552,0.998908,NO,65,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.744,-1.744,,,0.437,H,A,0.46,-0.39,3.012,,63.64,HHB,-1.38733,0.520039,0.00709258,0.998908 beta-lactamase_625_H156K,beta-lactamase_625_156,TEM-1,beta-lactamase_625,P62593,0.998911,NO,156,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-3.156,-2.967,-0.189,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.213352,0.00468596,0.998911 PSD95pdz3_Q358G,PSD95pdz3_358,PSD95pdz3,PSD95pdz3,P31016,0.998911,NO,358,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-1.699,-3.04,1.341,5.21282,,,,,14.8844,,,,APH,-1.531,0.0758425,0.000594893,0.998911 beta-lactamase_156_A278L,beta-lactamase_156_278,TEM-1,beta-lactamase_156,P62593,0.998912,NO,278,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.111618,0.0310297,0.998912 beta-lactamase_H151G,beta-lactamase_151,TEM-1,beta-lactamase,P62593,0.998912,NO,151,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-2.96,-2.515,-0.445,5.47408,0.594,H,A,0.35,0.1,1.843,,77.62,HBP,-2.34767,0.221079,0.00216946,0.998912 beta-lactamase_I171D,beta-lactamase_171,TEM-1,beta-lactamase,P62593,0.998912,NO,171,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-2.431,-3.888,1.457,5.22771,0.361,,B,1,0.53,1.66,,77.62,HHO,-1.55533,0.221079,0.00623355,0.998912 beta-lactamase_Q203G,beta-lactamase_203,TEM-1,beta-lactamase,P62593,0.998912,NO,203,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.168,-2.805,0.637,5.65296,0.47,H,A,0.12,-0.38,1.66,,65.38,BPP,-1.614,0.221079,0.00631514,0.998912 kka2_1:1_D33D,kka2_1:1_33,Kka2,kka2_1:1,P00552,0.998916,NO,33,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.186,-2.186,,,0.561,S,A,0.75,3.35,2.568,,71.59,PAH,-1.306,0.520039,0.00633568,0.998916 kka2_1:2_C31C,kka2_1:2_31,Kka2,kka2_1:2,P00552,0.998916,NO,31,C,C,CC,Special,Special,5.07,5.07,0,0,121,121,0,108.5,108.5,0,-2.246,-2.246,,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.295029,0.00681582,0.998916 beta-lactamase_2500_S96A,beta-lactamase_2500_96,TEM-1,beta-lactamase_2500,P62593,0.998922,NO,96,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.27,-2.75,0.48,,0.368,,b,0.27,0.39,32.348,32.348,73.78,HPP,-2.019,0.361275,0.00551835,0.998922 kka2_1:4_S40S,kka2_1:4_40,Kka2,kka2_1:4,P00552,0.998924,NO,40,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.645,-2.645,,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.168804,0.00693477,0.998924 PSD95pdz3_Q374M,PSD95pdz3_374,PSD95pdz3,PSD95pdz3,P31016,0.998924,NO,374,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-1.699,-3.937,2.238,5.38825,,,,,17.3289,,,,APH,-1.47,0.0758425,0.000372298,0.998924 kka2_1:4_A56A,kka2_1:4_56,Kka2,kka2_1:4,P00552,0.998928,NO,56,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.083,-2.083,,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.168804,0.00717715,0.998928 beta-lactamase_156_L47V,beta-lactamase_156_47,TEM-1,beta-lactamase_156,P62593,0.998931,NO,47,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.876,-2.564,0.688,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.111618,0.00439844,0.998931 beta-lactamase_625_K30C,beta-lactamase_625_30,TEM-1,beta-lactamase_625,P62593,0.998934,NO,30,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-2.307,-5.006,2.699,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.213352,0.00448593,0.998934 kka2_1:2_H124T,kka2_1:2_124,Kka2,kka2_1:2,P00552,0.998934,NO,124,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-0.84,-3.675,2.835,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.295029,0.00211296,0.998934 beta-lactamase_156_D174L,beta-lactamase_156_174,TEM-1,beta-lactamase_156,P62593,0.998935,NO,174,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.738,-3.808,3.07,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.111618,0.00125633,0.998935 kka2_1:4_E17E,kka2_1:4_17,Kka2,kka2_1:4,P00552,0.998938,NO,17,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.154,-2.154,,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.168804,0.00688738,0.998938 beta-lactamase_156_M184Q,beta-lactamase_156_184,TEM-1,beta-lactamase_156,P62593,0.998942,NO,184,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.593,-3.011,1.418,,,H,A,0.55,-0.87,1.671,,62.94,HHH,-1.41,0.111618,0.00356019,0.998942 kka2_1:4_G181G,kka2_1:4_181,Kka2,kka2_1:4,P00552,0.998942,NO,181,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-2.698,-2.698,,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.168804,0.00728319,0.998942 beta-lactamase_156_P60M,beta-lactamase_156_60,TEM-1,beta-lactamase_156,P62593,0.998946,NO,60,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-2.469,-4.701,2.232,,0.256,T,A,0.52,-0.56,2.947,,77.62,BOA,-1.97633,0.111618,0.00521318,0.998946 beta-lactamase_625_A222E,beta-lactamase_625_222,TEM-1,beta-lactamase_625,P62593,0.998948,NO,222,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.103,-3.646,1.543,,0.233,H,A,0.46,-0.25,1.448,,77.62,PHH,-1.63733,0.213352,0.00466094,0.998948 beta-lactamase_625_A278M,beta-lactamase_625_278,TEM-1,beta-lactamase_625,P62593,0.99895,NO,278,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.213352,0.0310297,0.99895 beta-lactamase_156_P250W,beta-lactamase_156_250,TEM-1,beta-lactamase_156,P62593,0.998952,NO,250,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.111618,0.00550899,0.998952 beta-lactamase_39_I277A,beta-lactamase_39_277,TEM-1,beta-lactamase_39,P62593,0.998954,NO,277,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.0495842,0.0169305,0.998954 beta-lactamase_156_H110L,beta-lactamase_156_110,TEM-1,beta-lactamase_156,P62593,0.998957,NO,110,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-1.706,-3.515,1.809,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.111618,0.00441499,0.998957 kka2_1:1_A35A,kka2_1:1_35,Kka2,kka2_1:1,P00552,0.998959,NO,35,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.127,-2.127,,,0.107,E,B,0.46,1.05,8.405,8.405,71.59,HHH,-1.31767,0.520039,0.00630016,0.998959 beta-lactamase_625_V31M,beta-lactamase_625_31,TEM-1,beta-lactamase_625,P62593,0.998961,NO,31,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.822,-3.184,1.362,,,H,A,0.44,-0.46,2.576,,73.78,BHB,-2.03767,0.213352,0.00478065,0.998961 beta-lactamase_39_P255G,beta-lactamase_39_255,TEM-1,beta-lactamase_39,P62593,0.998962,NO,255,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.0495842,0.00499612,0.998962 beta-lactamase_625_L47M,beta-lactamase_625_47,TEM-1,beta-lactamase_625,P62593,0.998963,NO,47,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.876,-2.629,0.753,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.213352,0.00439844,0.998963 kka2_1:8_V16V,kka2_1:8_16,Kka2,kka2_1:8,P00552,0.998963,NO,16,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-3.087,-3.087,,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.100394,0.00694011,0.998963 kka2_1:8_V16V,kka2_1:8_16,Kka2,kka2_1:8,P00552,0.998963,NO,16,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-3.087,-3.087,,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.100394,0.00694011,0.998963 beta-lactamase_W163M,beta-lactamase_163,TEM-1,beta-lactamase,P62593,0.998965,NO,163,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-1.843,-3.104,1.261,6.2765,0.467,,B,1.22,-0.5,3.642,,63.99,BHA,-1.269,0.221079,0.00418955,0.998965 Pab1_D160Y,Pab1_160,Pab1,Pab1,P04147,0.998966,NO,160,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.985,-4.205,3.22,,0.396,B,B,,1.12,,,,PAA,-1.30133,0.175299,0.000311977,0.998966 beta-lactamase_156_T186P,beta-lactamase_156_186,TEM-1,beta-lactamase_156,P62593,0.998967,NO,186,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.522,-3.945,1.423,,0.396,H,A,0.22,-0.28,16.606,16.606,77.62,HPP,-1.77633,0.111618,0.00485034,0.998967 beta-lactamase_156_E46L,beta-lactamase_156_46,TEM-1,beta-lactamase_156,P62593,0.998968,NO,46,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.94,-2.216,0.276,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.111618,0.00427568,0.998968 beta-lactamase_625_A148Y,beta-lactamase_625_148,TEM-1,beta-lactamase_625,P62593,0.99897,NO,148,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.757,-4.336,2.579,,0.379,H,A,0.46,-0.55,1.359,,72.73,PHH,-1.40167,0.213352,0.00547053,0.99897 beta-lactamase_625_G226R,beta-lactamase_625_226,TEM-1,beta-lactamase_625,P62593,0.998971,NO,226,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.461,-3.022,1.561,,0.701,T,l,0.29,-0.25,3.199,,74.48,HOH,-1.42933,0.213352,0.00665294,0.998971 beta-lactamase_0_K109E,beta-lactamase_0_109,TEM-1,beta-lactamase_0,P62593,0.998972,NO,109,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.734,-2.478,0.744,,0.787,G,A,2.34,2.21,15.473,15.473,72.73,ABB,-1.63333,0.0500837,0.00462493,0.998972 beta-lactamase_625_M127H,beta-lactamase_625_127,TEM-1,beta-lactamase_625,P62593,0.998973,NO,127,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-2.251,-4.786,2.535,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.213352,0.00437927,0.998973 kka2_1:2_Q26Q,kka2_1:2_26,Kka2,kka2_1:2,P00552,0.998973,NO,26,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.18,-2.18,,,0.448,E,B,0.4,0.44,5.022,,92.05,HPP,-2.11167,0.295029,0.00708962,0.998973 beta-lactamase_156_E61W,beta-lactamase_156_61,TEM-1,beta-lactamase_156,P62593,0.998975,NO,61,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.115,-5.544,3.429,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.111618,0.00440955,0.998975 beta-lactamase_39_V29A,beta-lactamase_39_29,TEM-1,beta-lactamase_39,P62593,0.998979,NO,29,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-2.856,-2.61,-0.246,,0.733,H,A,0.44,-0.78,1.287,,93.01,HHB,-2.24733,0.0495842,0.00318969,0.998979 kka2_1:8_A247A,kka2_1:8_247,Kka2,kka2_1:8,P00552,0.99898,NO,247,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.459,-2.459,,,1.01,S,A,0.46,0.65,18.904,18.904,92.05,HHH,-2.197,0.100394,0.0102428,0.99898 kka2_1:8_A247A,kka2_1:8_247,Kka2,kka2_1:8,P00552,0.99898,NO,247,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.459,-2.459,,,1.01,S,A,0.46,0.65,18.904,18.904,92.05,HHH,-2.197,0.100394,0.0102428,0.99898 kka2_1:8_G74W,kka2_1:8_74,Kka2,kka2_1:8,P00552,0.99898,NO,74,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.18,-5.433,4.253,,0.621,T,l,0.29,0.2,2.014,,64.39,POH,-1.91667,0.100394,0.00587035,0.99898 kka2_1:8_G74W,kka2_1:8_74,Kka2,kka2_1:8,P00552,0.99898,NO,74,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.18,-5.433,4.253,,0.621,T,l,0.29,0.2,2.014,,64.39,POH,-1.91667,0.100394,0.00587035,0.99898 beta-lactamase_625_M184A,beta-lactamase_625_184,TEM-1,beta-lactamase_625,P62593,0.998985,NO,184,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.593,-2.223,0.63,,,H,A,0.55,-0.87,2.765,,62.94,HHH,-1.41,0.213352,0.00356019,0.998985 beta-lactamase_39_N274H,beta-lactamase_39_274,TEM-1,beta-lactamase_39,P62593,0.998987,NO,274,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.0495842,0.0110418,0.998987 beta-lactamase_156_T198L,beta-lactamase_156_198,TEM-1,beta-lactamase_156,P62593,0.998993,NO,198,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.168,-3.433,1.265,,0.489,,B,0.22,-0.13,10.771,10.771,73.78,HPH,-1.98767,0.111618,0.004311,0.998993 PSD95pdz3_Q374C,PSD95pdz3_374,PSD95pdz3,PSD95pdz3,P31016,0.998993,NO,374,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-1.699,-4.769,3.07,5.38825,,,,,17.3289,,,,APH,-1.47,0.0758425,0.000372298,0.998993 beta-lactamase_39_H94E,beta-lactamase_39_94,TEM-1,beta-lactamase_39,P62593,0.998994,NO,94,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-2.5,-2.415,-0.085,,0.776,,B,0.17,1.24,11.583,11.583,77.62,HBH,-1.872,0.0495842,0.00389226,0.998994 beta-lactamase_156_L55G,beta-lactamase_156_55,TEM-1,beta-lactamase_156,P62593,0.998995,NO,55,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.86,-3.665,1.805,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.111618,0.00403741,0.998995 Pab1_D160L,Pab1_160,Pab1,Pab1,P04147,0.998995,NO,160,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.985,-3.625,2.64,,0.396,B,B,,1.12,,,,PAA,-1.30133,0.175299,0.000311977,0.998995 beta-lactamase_625_L73I,beta-lactamase_625_73,TEM-1,beta-lactamase_625,P62593,0.998996,NO,73,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.507,-2.52,1.013,,,H,A,0.55,-0.64,2.933,,67.83,HHH,-1.487,0.213352,0.00488983,0.998996 kka2_1:4_H106H,kka2_1:4_106,Kka2,kka2_1:4,P00552,0.998996,NO,106,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-3.13,-3.13,,,1.065,.,a,0.17,-0.95,16.74,16.74,71.59,PBH,-2.10433,0.168804,0.00730778,0.998996 kka2_1:8_A144V,kka2_1:8_144,Kka2,kka2_1:8,P00552,0.998996,NO,144,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.859,-2.095,1.236,,,H,A,1.04,0.21,1.118,,52.65,BHB,-1.72933,0.100394,0.00231095,0.998996 kka2_1:8_A144V,kka2_1:8_144,Kka2,kka2_1:8,P00552,0.998996,NO,144,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.859,-2.095,1.236,,,H,A,1.04,0.21,1.118,,52.65,BHB,-1.72933,0.100394,0.00231095,0.998996 beta-lactamase_625_H94R,beta-lactamase_625_94,TEM-1,beta-lactamase_625,P62593,0.999009,NO,94,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-2.5,-2.531,0.031,,0.776,,B,0.17,1.24,19.42,19.42,77.62,HBH,-1.872,0.213352,0.00389226,0.999009 beta-lactamase_39_P224A,beta-lactamase_39_224,TEM-1,beta-lactamase_39,P62593,0.99901,NO,224,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.893,-3.071,2.178,,0.383,,B,0.52,-0.3,3.169,,74.48,HOH,-1.26433,0.0495842,0.00189564,0.99901 kka2_1:4_T125T,kka2_1:4_125,Kka2,kka2_1:4,P00552,0.99901,NO,125,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.622,-2.622,,,0.791,T,A,0.82,0.33,1.612,,92.05,BPH,-1.56933,0.168804,0.00821755,0.99901 kka2_1:2_S54S,kka2_1:2_54,Kka2,kka2_1:2,P00552,0.999011,NO,54,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.471,-2.471,,,0.408,S,b,0.27,1.01,0.393,,71.59,HPO,-2.259,0.295029,0.00782867,0.999011 beta-lactamase_156_S51A,beta-lactamase_156_51,TEM-1,beta-lactamase_156,P62593,0.999013,NO,51,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.526,-2.32,0.794,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.111618,0.00504821,0.999013 hsp90_M589M,hsp90_589,hsp90,hsp90,P02829,0.999014,NO,589,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-3.858,-3.858,,4.72723,0.032,H,A,0.84,0.31,,,,PHA,-3.24233,0.368192,0.000222939,0.999014 hsp90_W585W,hsp90_585,hsp90,hsp90,P02829,0.999014,NO,585,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-4.251,-4.251,,5.31455,0.508,,B,1.22,0.43,,,,OHP,-3.17533,0.368192,0.000222939,0.999014 kka2_1:4_E235E,kka2_1:4_235,Kka2,kka2_1:4,P00552,0.999014,NO,235,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.955,-1.955,,,0.631,H,A,1.04,0.12,23.175,23.175,65.53,OAH,-2.07267,0.168804,0.0102806,0.999014 beta-lactamase_156_N50H,beta-lactamase_156_50,TEM-1,beta-lactamase_156,P62593,0.999017,NO,50,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-2.979,-3.33,0.351,,0.912,T,A,0.61,1.24,13.295,13.295,77.62,HPP,-2.134,0.111618,0.0047211,0.999017 beta-lactamase_0_V82W,beta-lactamase_0_82,TEM-1,beta-lactamase_0,P62593,0.999019,NO,82,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.325,-5.421,4.096,,0.267,H,A,0.44,0.08,1.893,,93.01,BHA,-1.28567,0.0500837,0.00397046,0.999019 beta-lactamase_2500_A268R,beta-lactamase_2500_268,TEM-1,beta-lactamase_2500,P62593,0.999019,NO,268,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.361275,0.0102525,0.999019 beta-lactamase_2500_R189C,beta-lactamase_2500_189,TEM-1,beta-lactamase_2500,P62593,0.999024,NO,189,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.844,-5.229,3.385,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.361275,0.0050699,0.999024 kka2_1:2_A108A,kka2_1:2_108,Kka2,kka2_1:2,P00552,0.999026,NO,108,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.061,-2.061,,,0.243,.,B,0.46,-1.34,2.462,,71.59,HHO,-1.57033,0.295029,0.00751209,0.999026 beta-lactamase_625_K144W,beta-lactamase_625_144,TEM-1,beta-lactamase_625,P62593,0.999027,NO,144,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-2.388,-5.522,3.134,,0.863,H,A,2.34,1.27,2.313,,77.62,OBA,-1.904,0.213352,0.00481141,0.999027 beta-lactamase_625_M270L,beta-lactamase_625_270,TEM-1,beta-lactamase_625,P62593,0.999027,NO,270,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.213352,0.00767762,0.999027 beta-lactamase_39_S96P,beta-lactamase_39_96,TEM-1,beta-lactamase_39,P62593,0.999028,NO,96,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.27,-2.878,0.608,,0.368,,b,0.27,0.39,2.516,,73.78,HPP,-2.019,0.0495842,0.00551835,0.999028 kka2_1:4_Q26Q,kka2_1:4_26,Kka2,kka2_1:4,P00552,0.999028,NO,26,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.18,-2.18,,,0.448,E,B,0.4,0.44,5.022,,92.05,HPP,-2.11167,0.168804,0.00708962,0.999028 beta-lactamase_625_E238Y,beta-lactamase_625_238,TEM-1,beta-lactamase_625,P62593,0.999029,NO,238,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.213352,0.00743256,0.999029 kka2_1:4_G74G,kka2_1:4_74,Kka2,kka2_1:4,P00552,0.999032,NO,74,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.18,-1.18,,,0.621,T,l,0.75,0.2,1.032,,64.39,POH,-1.91667,0.168804,0.00587035,0.999032 beta-lactamase_39_D161N,beta-lactamase_39_161,TEM-1,beta-lactamase_39,P62593,0.999038,NO,161,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.891,-3.293,2.402,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.0495842,0.000897697,0.999038 beta-lactamase_2500_A211E,beta-lactamase_2500_211,TEM-1,beta-lactamase_2500,P62593,0.999039,NO,211,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.896,-2.447,0.551,,0.369,T,A,0.46,-0.69,2.061,,77.62,AHA,-1.94633,0.361275,0.00648183,0.999039 kka2_1:2_R18R,kka2_1:2_18,Kka2,kka2_1:2,P00552,0.999039,NO,18,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.055,-2.055,,,0.474,T,A,1.2,0.54,8.405,8.405,71.59,ABH,-1.821,0.295029,0.00724065,0.999039 beta-lactamase_Q265I,beta-lactamase_265,TEM-1,beta-lactamase,P62593,0.999041,NO,265,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.58,-4.09,1.51,6.62674,1.116,,A,0.03,1.17,12.514,12.514,69.58,PPH,-1.978,0.221079,0.00811926,0.999041 beta-lactamase_39_S122G,beta-lactamase_39_122,TEM-1,beta-lactamase_39,P62593,0.999042,NO,122,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.406,-3.475,1.069,,0.352,H,A,0.27,-0.54,2.004,,77.62,OPH,-1.39767,0.0495842,0.00497825,0.999042 beta-lactamase_156_V106N,beta-lactamase_156_106,TEM-1,beta-lactamase_156,P62593,0.999046,NO,106,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.218,-4.217,2.999,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.111618,0.00304168,0.999046 kka2_1:8_I2I,kka2_1:8_2,Kka2,kka2_1:8,P00552,0.999046,NO,2,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.787,-1.787,,,,,,,,,,71.59,HHA,-1.92433,0.100394,0.00246644,0.999046 kka2_1:8_I2I,kka2_1:8_2,Kka2,kka2_1:8,P00552,0.999046,NO,2,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.787,-1.787,,,,,,,,,,71.59,HHA,-1.92433,0.100394,0.00246644,0.999046 beta-lactamase_2500_S96D,beta-lactamase_2500_96,TEM-1,beta-lactamase_2500,P62593,0.999047,NO,96,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.27,-3.641,1.371,,0.368,,b,0.27,0.39,32.348,32.348,73.78,HPP,-2.019,0.361275,0.00551835,0.999047 beta-lactamase_39_A278V,beta-lactamase_39_278,TEM-1,beta-lactamase_39,P62593,0.999051,NO,278,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.0495842,0.0310297,0.999051 beta-lactamase_2500_D252M,beta-lactamase_2500_252,TEM-1,beta-lactamase_2500,P62593,0.999055,NO,252,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.94,,,,0.766,,B,1.59,1.16,,,67.83,OAO,-2.0965,0.361275,0.00575769,0.999055 kka2_1:2_Q27Q,kka2_1:2_27,Kka2,kka2_1:2,P00552,0.999055,NO,27,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-1.659,-1.659,,,0.608,.,A,0.64,0.71,0.521,,65.53,PPP,-1.90733,0.295029,0.00595365,0.999055 beta-lactamase_156_K144E,beta-lactamase_156_144,TEM-1,beta-lactamase_156,P62593,0.999058,NO,144,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-2.388,-2.372,-0.016,,0.863,H,A,2.34,1.27,2.073,,77.62,OBA,-1.904,0.111618,0.00481141,0.999058 beta-lactamase_625_N173G,beta-lactamase_625_173,TEM-1,beta-lactamase_625,P62593,0.999058,NO,173,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-2.663,-1.002,-1.661,,1.044,T,l,0.61,1.25,1.426,,77.62,OPA,-1.46633,0.213352,0.0033769,0.999058 kka2_1:2_R122R,kka2_1:2_122,Kka2,kka2_1:2,P00552,0.999058,NO,122,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.175,-2.175,,,0.487,H,A,1.2,0.26,16.436,16.436,71.59,BBH,-1.53833,0.295029,0.00736512,0.999058 beta-lactamase_39_G85S,beta-lactamase_39_85,TEM-1,beta-lactamase_39,P62593,0.999062,NO,85,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.011,-3.264,2.253,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.0495842,0.00252173,0.999062 kka2_1:2_E17E,kka2_1:2_17,Kka2,kka2_1:2,P00552,0.999064,NO,17,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.154,-2.154,,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.295029,0.00688738,0.999064 kka2_1:1_E230E,kka2_1:1_230,Kka2,kka2_1:1,P00552,0.999065,NO,230,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.672,-2.672,,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.520039,0.00920051,0.999065 kka2_1:1_I221I,kka2_1:1_221,Kka2,kka2_1:1,P00552,0.999065,NO,221,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.739,-1.739,,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.520039,0.00945908,0.999065 beta-lactamase_625_E175K,beta-lactamase_625_175,TEM-1,beta-lactamase_625,P62593,0.999071,NO,175,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.336,-2.673,0.337,,0.551,,A,1.04,1.05,8.527,8.527,77.62,AAB,-1.31233,0.213352,0.00482205,0.999071 kka2_1:4_E230E,kka2_1:4_230,Kka2,kka2_1:4,P00552,0.999071,NO,230,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.672,-2.672,,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.168804,0.00920051,0.999071 kka2_1:2_S68S,kka2_1:2_68,Kka2,kka2_1:2,P00552,0.999074,NO,68,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.623,-2.623,,,0.48,H,A,0.27,-0.1,2.655,,71.59,HPH,-1.40767,0.295029,0.00608265,0.999074 beta-lactamase_39_E56D,beta-lactamase_39_56,TEM-1,beta-lactamase_39,P62593,0.999078,NO,56,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.043,-3.248,1.205,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.0495842,0.00238534,0.999078 beta-lactamase_39_R189I,beta-lactamase_39_189,TEM-1,beta-lactamase_39,P62593,0.999082,NO,189,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.844,-4.147,2.303,,0.278,H,A,1.2,1.01,12.11,12.11,72.73,HBB,-1.668,0.0495842,0.0050699,0.999082 kka2_1:4_A41A,kka2_1:4_41,Kka2,kka2_1:4,P00552,0.999082,NO,41,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.879,-1.879,,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.168804,0.00543332,0.999082 kka2_1:4_D180D,kka2_1:4_180,Kka2,kka2_1:4,P00552,0.999082,NO,180,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.416,-2.416,,,1.03,S,a,0.29,1.5,14.668,14.668,71.59,OAO,-2.02933,0.168804,0.00756412,0.999082 kka2_1:4_G10G,kka2_1:4_10,Kka2,kka2_1:4,P00552,0.999082,NO,10,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.921,-1.921,,,,,,,,1.862,,71.59,HOP,-2.10733,0.168804,0.00289233,0.999082 beta-lactamase_625_L136M,beta-lactamase_625_136,TEM-1,beta-lactamase_625,P62593,0.999083,NO,136,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.232,-2.988,1.756,,,H,A,0.55,-0.34,0.336,,48.95,HHH,-1.088,0.213352,0.00442304,0.999083 beta-lactamase_39_W163S,beta-lactamase_39_163,TEM-1,beta-lactamase_39,P62593,0.999087,NO,163,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-1.843,-3.614,1.771,,0.467,,B,0.47,-0.5,15.095,15.095,63.99,BHA,-1.269,0.0495842,0.00418955,0.999087 beta-lactamase_625_N173Y,beta-lactamase_625_173,TEM-1,beta-lactamase_625,P62593,0.999089,NO,173,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-2.663,-4.409,1.746,,1.044,T,l,0.61,1.25,1.426,,77.62,OPA,-1.46633,0.213352,0.0033769,0.999089 kka2_1:4_K175K,kka2_1:4_175,Kka2,kka2_1:4,P00552,0.999089,NO,175,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-2.897,-2.897,,,0.579,H,A,1.3,0.51,15.629,15.629,71.59,HBH,-1.82333,0.168804,0.00693093,0.999089 beta-lactamase_2500_H94W,beta-lactamase_2500_94,TEM-1,beta-lactamase_2500,P62593,0.999093,NO,94,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-2.5,-5.512,3.012,,0.776,,B,0.17,1.24,1.176,,77.62,HBH,-1.872,0.361275,0.00389226,0.999093 kka2_1:4_M178M,kka2_1:4_178,Kka2,kka2_1:4,P00552,0.999093,NO,178,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-3.206,-3.206,,,0.554,.,b,0.55,0.68,9.913,9.913,71.59,BHO,-2.154,0.168804,0.00717253,0.999093 beta-lactamase_625_T27L,beta-lactamase_625_27,TEM-1,beta-lactamase_625,P62593,0.999096,NO,27,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.905,-2.65,0.745,,0.007,H,A,0.22,-0.37,3.72,,93.01,APH,-1.97933,0.213352,0.00306559,0.999096 kka2_1:4_S114S,kka2_1:4_114,Kka2,kka2_1:4,P00552,0.999096,NO,114,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.527,-2.527,,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.168804,0.00705262,0.999096 kka2_1:4_A137A,kka2_1:4_137,Kka2,kka2_1:4,P00552,0.999104,NO,137,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.156,-2.156,,,0.029,H,A,0.46,0.34,2.227,,63.26,PHB,-2.559,0.168804,0.00515054,0.999104 beta-lactamase_39_E238M,beta-lactamase_39_238,TEM-1,beta-lactamase_39,P62593,0.999105,NO,238,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.0495842,0.00743256,0.999105 beta-lactamase_625_Q37D,beta-lactamase_625_37,TEM-1,beta-lactamase_625,P62593,0.999105,NO,37,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.134,-2.904,0.77,,0.613,H,A,0.64,1.98,1.318,,73.08,APH,-2.06967,0.213352,0.00425833,0.999105 kka2_1:2_K175K,kka2_1:2_175,Kka2,kka2_1:2,P00552,0.999105,NO,175,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-2.897,-2.897,,,0.579,H,A,1.3,0.51,15.629,15.629,71.59,HBH,-1.82333,0.295029,0.00693093,0.999105 beta-lactamase_625_F149S,beta-lactamase_625_149,TEM-1,beta-lactamase_625,P62593,0.999108,NO,149,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.299,-2.783,1.484,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.213352,0.00418462,0.999108 beta-lactamase_156_G39V,beta-lactamase_156_39,TEM-1,beta-lactamase_156,P62593,0.999109,NO,39,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.864,-3.813,1.949,,0.701,T,L,0.29,0.47,1.454,,77.62,HOH,-1.53633,0.111618,0.00487611,0.999109 hsp90_F583F,hsp90_583,hsp90,hsp90,P02829,0.999111,NO,583,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-3.22,-3.22,,5.28185,1.112,S,l,1.1,0.87,,,,PHO,-3.003,0.368192,0.000222939,0.999111 beta-lactamase_156_V214G,beta-lactamase_156_214,TEM-1,beta-lactamase_156,P62593,0.999112,NO,214,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.299,-3.571,2.272,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.111618,0.00628442,0.999112 beta-lactamase_625_A278G,beta-lactamase_625_278,TEM-1,beta-lactamase_625,P62593,0.999112,NO,278,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.213352,0.0310297,0.999112 kka2_1:8_V242V,kka2_1:8_242,Kka2,kka2_1:8,P00552,0.999112,NO,242,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-2.687,-2.687,,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.100394,0.0102575,0.999112 kka2_1:8_V242V,kka2_1:8_242,Kka2,kka2_1:8,P00552,0.999112,NO,242,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-2.687,-2.687,,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.100394,0.0102575,0.999112 beta-lactamase_A266R,beta-lactamase_266,TEM-1,beta-lactamase,P62593,0.999113,NO,266,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.369,-2.973,1.604,5.02057,0.175,S,B,0.52,0.07,1.832,,64.34,PHP,-2.08567,0.221079,0.0140785,0.999113 beta-lactamase_156_E195G,beta-lactamase_156_195,TEM-1,beta-lactamase_156,P62593,0.999114,NO,195,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.186,-2.611,0.425,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.111618,0.00496565,0.999114 kka2_1:2_A129A,kka2_1:2_129,Kka2,kka2_1:2,P00552,0.999115,NO,129,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.656,-1.656,,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.295029,0.00726862,0.999115 E1_Ubiquitin_F45I,E1_Ubiquitin_45,Uba1,E1_Ubiquitin,P0CG63,0.999116,NO,45,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.149,-3.152,2.003,,0.26,E,B,,-0.99,,,,HHH,-1.316,0.18783,0.00193245,0.999116 E1_Ubiquitin_F45W,E1_Ubiquitin_45,Uba1,E1_Ubiquitin,P0CG63,0.999116,NO,45,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.149,-4.24,3.091,,0.26,E,B,,-0.99,,,,HHH,-1.316,0.18783,0.00193245,0.999116 E1_Ubiquitin_Q41P,E1_Ubiquitin_41,Uba1,E1_Ubiquitin,P0CG63,0.999116,NO,41,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-1.25,-3.472,2.222,,0.017,E,B,,-0.98,,,,PPB,-1.344,0.18783,0.00215097,0.999116 beta-lactamase_156_L100S,beta-lactamase_156_100,TEM-1,beta-lactamase_156,P62593,0.999117,NO,100,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.218,-3.715,2.497,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.111618,0.00413885,0.999117 beta-lactamase_625_A268N,beta-lactamase_625_268,TEM-1,beta-lactamase_625,P62593,0.999117,NO,268,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.213352,0.0102525,0.999117 beta-lactamase_39_K109E,beta-lactamase_39_109,TEM-1,beta-lactamase_39,P62593,0.999118,NO,109,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.734,-2.478,0.744,,0.787,G,A,2.34,2.21,7.243,,72.73,ABB,-1.63333,0.0495842,0.00462493,0.999118 beta-lactamase_2500_E102D,beta-lactamase_2500_102,TEM-1,beta-lactamase_2500,P62593,0.99912,NO,102,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.118,-2.118,0,,0.722,S,B,1.04,1.82,1.336,,73.08,HAH,-1.581,0.361275,0.00486633,0.99912 beta-lactamase_0_D113Y,beta-lactamase_0_113,TEM-1,beta-lactamase_0,P62593,0.999123,NO,113,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.829,-4.441,2.612,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.0500837,0.00474112,0.999123 beta-lactamase_39_R257I,beta-lactamase_39_257,TEM-1,beta-lactamase_39,P62593,0.999125,NO,257,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.0495842,0.00756629,0.999125 kka2_1:4_R18R,kka2_1:4_18,Kka2,kka2_1:4,P00552,0.999125,NO,18,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.055,-2.055,,,0.474,T,A,1.2,0.54,8.405,8.405,71.59,ABH,-1.821,0.168804,0.00724065,0.999125 kka2_1:8_G6G,kka2_1:8_6,Kka2,kka2_1:8,P00552,0.999128,NO,6,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.685,-1.685,,,,,,,,,,71.59,AOH,-1.639,0.100394,0.00204693,0.999128 kka2_1:8_G6G,kka2_1:8_6,Kka2,kka2_1:8,P00552,0.999128,NO,6,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.685,-1.685,,,,,,,,,,71.59,AOH,-1.639,0.100394,0.00204693,0.999128 kka2_1:8_G74G,kka2_1:8_74,Kka2,kka2_1:8,P00552,0.999128,NO,74,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.18,-1.18,,,0.621,T,l,0.29,0.2,2.014,,64.39,POH,-1.91667,0.100394,0.00587035,0.999128 kka2_1:8_G74G,kka2_1:8_74,Kka2,kka2_1:8,P00552,0.999128,NO,74,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.18,-1.18,,,0.621,T,l,0.29,0.2,2.014,,64.39,POH,-1.91667,0.100394,0.00587035,0.999128 kka2_1:8_K138W,kka2_1:8_138,Kka2,kka2_1:8,P00552,0.999128,NO,138,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-2.5,-5.6,3.1,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.100394,0.00628542,0.999128 kka2_1:8_K138W,kka2_1:8_138,Kka2,kka2_1:8,P00552,0.999128,NO,138,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-2.5,-5.6,3.1,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.100394,0.00628542,0.999128 kka2_1:8_Q252Q,kka2_1:8_252,Kka2,kka2_1:8,P00552,0.999128,NO,252,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.63,-2.63,,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.100394,0.0121001,0.999128 kka2_1:8_Q252Q,kka2_1:8_252,Kka2,kka2_1:8,P00552,0.999128,NO,252,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.63,-2.63,,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.100394,0.0121001,0.999128 beta-lactamase_156_F149D,beta-lactamase_156_149,TEM-1,beta-lactamase_156,P62593,0.999129,NO,149,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.299,-3.957,2.658,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.111618,0.00418462,0.999129 beta-lactamase_39_P60Y,beta-lactamase_39_60,TEM-1,beta-lactamase_39,P62593,0.999129,NO,60,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-2.469,-4.292,1.823,,0.256,T,A,0.52,-0.56,21.37,21.37,77.62,BOA,-1.97633,0.0495842,0.00521318,0.999129 beta-lactamase_156_L49G,beta-lactamase_156_49,TEM-1,beta-lactamase_156,P62593,0.99913,NO,49,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.897,-3.581,1.684,,0.131,T,A,0.55,0.04,3.112,,64.69,AHP,-1.99233,0.111618,0.00401477,0.99913 beta-lactamase_2500_I54M,beta-lactamase_2500_54,TEM-1,beta-lactamase_2500,P62593,0.99913,NO,54,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-2.838,-3.13,0.292,,0.669,E,B,0.48,-0.14,3.946,,73.78,BHH,-2.337,0.361275,0.00403589,0.99913 Pab1_A182V,Pab1_182,Pab1,Pab1,P04147,0.999132,NO,182,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.013,-2.896,1.883,,,H,A,0.17,0.79,,,,AHH,-1.36067,0.175299,0.000289034,0.999132 beta-lactamase_625_L196Y,beta-lactamase_625_196,TEM-1,beta-lactamase_625,P62593,0.999134,NO,196,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-2.478,-4.286,1.808,,0.518,S,A,0.55,1.35,12.152,12.152,77.62,AHH,-1.839,0.213352,0.00512144,0.999134 beta-lactamase_156_L89H,beta-lactamase_156_89,TEM-1,beta-lactamase_156,P62593,0.999136,NO,89,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.096,-4.892,3.796,,0.168,T,A,0.55,0.63,2.633,,64.34,PHO,-1.75767,0.111618,0.00207068,0.999136 kka2_1:4_R143R,kka2_1:4_143,Kka2,kka2_1:4,P00552,0.999136,NO,143,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.525,-2.525,,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.168804,0.00662247,0.999136 beta-lactamase_39_R63I,beta-lactamase_39_63,TEM-1,beta-lactamase_39,P62593,0.999137,NO,63,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-0.943,-3.824,2.881,,0.218,,B,1.2,-0.31,0.326,,44.06,ABH,-0.992333,0.0495842,0.00126938,0.999137 beta-lactamase_2500_H156Y,beta-lactamase_2500_156,TEM-1,beta-lactamase_2500,P62593,0.999138,NO,156,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-3.156,-4.359,1.203,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.361275,0.00468596,0.999138 beta-lactamase_39_I258L,beta-lactamase_39_258,TEM-1,beta-lactamase_39,P62593,0.99914,NO,258,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.0495842,0.007931,0.99914 WW_domain_S183V,WW_domain_183,Yap65,WW_domain,P46937,0.999143,NO,183,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.95,-3.414,1.464,5.35576,,,,,,1.594,,83.93,PPP,-1.48733,0.153962,0.00445513,0.999143 kka2_1:8_A248A,kka2_1:8_248,Kka2,kka2_1:8,P00552,0.999145,NO,248,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.124,-2.124,,,0.825,S,b,1.04,0.46,11.329,11.329,92.05,HHO,-2.15,0.100394,0.0125484,0.999145 kka2_1:8_A248A,kka2_1:8_248,Kka2,kka2_1:8,P00552,0.999145,NO,248,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.124,-2.124,,,0.825,S,b,1.04,0.46,11.329,11.329,92.05,HHO,-2.15,0.100394,0.0125484,0.999145 kka2_1:4_A65A,kka2_1:4_65,Kka2,kka2_1:4,P00552,0.999147,NO,65,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.744,-1.744,,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.168804,0.00709258,0.999147 kka2_1:1_M1M,kka2_1:1_1,Kka2,kka2_1:1,P00552,0.999148,NO,1,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.787,-1.787,,,,,,,,3.101,,62.12,NAHH,-1.787,0.520039,0.00251939,0.999148 beta-lactamase_625_P250V,beta-lactamase_625_250,TEM-1,beta-lactamase_625,P62593,0.999149,NO,250,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.213352,0.00550899,0.999149 kka2_1:2_A87A,kka2_1:2_87,Kka2,kka2_1:2,P00552,0.999152,NO,87,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.917,-1.917,,,1.039,S,L,0.46,1.57,22.675,22.675,65.53,AHO,-1.822,0.295029,0.00791281,0.999152 beta-lactamase_156_L205W,beta-lactamase_156_205,TEM-1,beta-lactamase_156,P62593,0.999154,NO,205,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.922,-4.959,4.037,,,H,A,0.55,-0.46,0.678,,42.31,PHH,-1.57767,0.111618,0.00255802,0.999154 beta-lactamase_2500_Q97D,beta-lactamase_2500_97,TEM-1,beta-lactamase_2500,P62593,0.999154,NO,97,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.072,-3.567,1.495,,0.823,G,A,0.64,2.42,1.157,,77.62,PPP,-2.43833,0.361275,0.0045116,0.999154 kka2_1:4_E111E,kka2_1:4_111,Kka2,kka2_1:4,P00552,0.999154,NO,111,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.28,-2.28,,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.168804,0.00746789,0.999154 kka2_1:4_S68S,kka2_1:4_68,Kka2,kka2_1:4,P00552,0.999154,NO,68,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.623,-2.623,,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.168804,0.00608265,0.999154 beta-lactamase_39_R92M,beta-lactamase_39_92,TEM-1,beta-lactamase_39,P62593,0.999155,NO,92,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.718,-3.339,1.621,,0.479,E,B,1.2,1.36,0.389,,65.38,BBH,-1.50367,0.0495842,0.00429626,0.999155 beta-lactamase_156_L79V,beta-lactamase_156_79,TEM-1,beta-lactamase_156,P62593,0.999159,NO,79,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.842,-2.879,2.037,,0.007,H,A,0.55,-0.16,1.831,,50.35,HHP,-1.44333,0.111618,0.000947397,0.999159 beta-lactamase_I171F,beta-lactamase_171,TEM-1,beta-lactamase,P62593,0.999159,NO,171,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-2.431,-3.175,0.744,5.22771,0.361,,B,1,0.53,1.66,,77.62,HHO,-1.55533,0.221079,0.00623355,0.999159 kka2_1:2_P167P,kka2_1:2_167,Kka2,kka2_1:2,P00552,0.999162,NO,167,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-2.403,-2.403,,,0.18,H,A,0.52,0.75,3.6,,64.39,HOH,-2.26633,0.295029,0.00543203,0.999162 beta-lactamase_2500_A268H,beta-lactamase_2500_268,TEM-1,beta-lactamase_2500,P62593,0.999163,NO,268,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.361275,0.0102525,0.999163 beta-lactamase_39_E145V,beta-lactamase_39_145,TEM-1,beta-lactamase_39,P62593,0.999164,NO,145,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.357,-3.665,1.308,,0.545,H,A,1.04,0.79,1.199,,77.62,BAH,-2.069,0.0495842,0.00553285,0.999164 kka2_1:4_S54S,kka2_1:4_54,Kka2,kka2_1:4,P00552,0.999168,NO,54,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.471,-2.471,,,0.408,S,b,0.27,1.01,17.332,17.332,71.59,HPO,-2.259,0.168804,0.00782867,0.999168 beta-lactamase_156_D33F,beta-lactamase_156_33,TEM-1,beta-lactamase_156,P62593,0.999171,NO,33,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.321,-4.288,1.967,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.111618,0.00435556,0.999171 beta-lactamase_156_Y95V,beta-lactamase_156_95,TEM-1,beta-lactamase_156,P62593,0.999172,NO,95,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-1.715,-2.446,0.731,,0.122,,b,0.21,-0.37,2.341,,77.62,BHP,-2.16167,0.111618,0.00479449,0.999172 beta-lactamase_156_N168T,beta-lactamase_156_168,TEM-1,beta-lactamase_156,P62593,0.999177,NO,168,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-1.029,-2.214,1.185,,0.113,G,A,0.61,-0.4,1.014,,44.41,HPA,-1.13233,0.111618,0.00288667,0.999177 beta-lactamase_625_P217W,beta-lactamase_625_217,TEM-1,beta-lactamase_625,P62593,0.999177,NO,217,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-2.062,-5.565,3.503,,0.496,I,A,0.52,-0.33,1.087,,74.48,OOH,-1.64333,0.213352,0.00463211,0.999177 kka2_1:4_A129A,kka2_1:4_129,Kka2,kka2_1:4,P00552,0.999179,NO,129,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.656,-1.656,,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.168804,0.00726862,0.999179 kka2_1:4_V75V,kka2_1:4_75,Kka2,kka2_1:4,P00552,0.999179,NO,75,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-2.06,-2.06,,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.168804,0.00693733,0.999179 beta-lactamase_39_L47T,beta-lactamase_39_47,TEM-1,beta-lactamase_39,P62593,0.99918,NO,47,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.876,-2.727,0.851,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.0495842,0.00439844,0.99918 beta-lactamase_2500_Q267P,beta-lactamase_2500_267,TEM-1,beta-lactamase_2500,P62593,0.999181,NO,267,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.361275,0.0102128,0.999181 kka2_1:4_Q219V,kka2_1:4_219,Kka2,kka2_1:4,P00552,0.999183,NO,219,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-0.93,-3.601,2.671,,0.088,H,A,0.64,-0.85,1.537,,50,HPA,-1.05167,0.168804,0.00237913,0.999183 beta-lactamase_156_L28Q,beta-lactamase_156_28,TEM-1,beta-lactamase_156,P62593,0.999184,NO,28,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.579,-2.97,1.391,,0.277,H,A,0.55,-0.16,3.262,,93.01,PHH,-2.11333,0.111618,0.00359321,0.999184 beta-lactamase_625_G226H,beta-lactamase_625_226,TEM-1,beta-lactamase_625,P62593,0.999184,NO,226,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.461,-4.656,3.195,,0.701,T,l,0.29,-0.25,3.199,,74.48,HOH,-1.42933,0.213352,0.00665294,0.999184 beta-lactamase_2500_R189Q,beta-lactamase_2500_189,TEM-1,beta-lactamase_2500,P62593,0.999186,NO,189,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.844,-2.262,0.418,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.361275,0.0050699,0.999186 kka2_1:1_L7L,kka2_1:1_7,Kka2,kka2_1:1,P00552,0.99919,NO,7,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.926,-1.926,,,,,,,,18.934,18.934,71.59,OHB,-2.12333,0.520039,0.00269456,0.99919 beta-lactamase_39_L197S,beta-lactamase_39_197,TEM-1,beta-lactamase_39,P62593,0.999199,NO,197,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.853,-3.532,2.679,,0.007,S,B,0.55,0.33,1.559,,60.14,HHP,-1.833,0.0495842,0.00144602,0.999199 kka2_1:4_A87A,kka2_1:4_87,Kka2,kka2_1:4,P00552,0.9992,NO,87,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.917,-1.917,,,1.039,S,L,0.46,1.57,22.675,22.675,65.53,AHO,-1.822,0.168804,0.00791281,0.9992 beta-lactamase_2500_A148H,beta-lactamase_2500_148,TEM-1,beta-lactamase_2500,P62593,0.999203,NO,148,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.757,-3.344,1.587,,0.379,H,A,0.46,-0.55,2.117,,72.73,PHH,-1.40167,0.361275,0.00547053,0.999203 kka2_1:1_T146T,kka2_1:1_146,Kka2,kka2_1:1,P00552,0.999208,NO,146,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.978,-2.978,,,0.281,H,A,0.82,0.78,2.105,,92.05,BPB,-1.96833,0.520039,0.00606474,0.999208 kka2_1:2_G10G,kka2_1:2_10,Kka2,kka2_1:2,P00552,0.999209,NO,10,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.921,-1.921,,,,,,,,2.192,,71.59,HOP,-2.10733,0.295029,0.00289233,0.999209 beta-lactamase_156_E279F,beta-lactamase_156_279,TEM-1,beta-lactamase_156,P62593,0.99921,NO,279,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.111618,0.0192826,0.99921 kka2_1:4_Q61Q,kka2_1:4_61,Kka2,kka2_1:4,P00552,0.999211,NO,61,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.982,-2.982,,,0.591,H,A,0.64,0.41,3.484,,65.53,HPA,-1.85667,0.168804,0.00612092,0.999211 beta-lactamase_D36N,beta-lactamase_36,TEM-1,beta-lactamase,P62593,0.999215,NO,36,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.732,-3.002,0.27,5.39764,0.555,H,A,0.11,1.17,13.689,13.689,77.62,AAP,-1.91167,0.221079,0.00476483,0.999215 beta-lactamase_H151N,beta-lactamase_151,TEM-1,beta-lactamase,P62593,0.999215,NO,151,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-2.96,-3.49,0.53,5.47408,0.594,H,A,0.35,0.1,1.843,,77.62,HBP,-2.34767,0.221079,0.00216946,0.999215 PSD95pdz3_L349Q,PSD95pdz3_349,PSD95pdz3,PSD95pdz3,P31016,0.999216,NO,349,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.347,-3.806,2.459,5.14696,,,,,24.6438,,,,AHP,-1.37667,0.0758425,0.00071841,0.999216 kka2_1:4_D52D,kka2_1:4_52,Kka2,kka2_1:4,P00552,0.999218,NO,52,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.271,-2.271,,,0.22,E,B,0.75,0.8,0.349,,71.59,PAH,-2.38367,0.168804,0.00175694,0.999218 beta-lactamase_A148V,beta-lactamase_148,TEM-1,beta-lactamase,P62593,0.999221,NO,148,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.757,-3.631,1.874,5.28111,0.379,H,A,0.52,-0.55,2.117,,72.73,PHH,-1.40167,0.221079,0.00547053,0.999221 beta-lactamase_39_Q204R,beta-lactamase_39_204,TEM-1,beta-lactamase_39,P62593,0.999222,NO,204,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-1.382,-2.322,0.94,,0.204,H,A,0.64,0.09,0.489,,66.08,PPH,-1.49067,0.0495842,0.00364106,0.999222 beta-lactamase_625_M180F,beta-lactamase_625_180,TEM-1,beta-lactamase_625,P62593,0.999224,NO,180,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-2.795,-3.981,1.186,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.213352,0.00552048,0.999224 kka2_1:1_H8H,kka2_1:1_8,Kka2,kka2_1:1,P00552,0.999225,NO,8,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-2.759,-2.759,,,,,,,,16.971,16.971,71.59,HBH,-2.25467,0.520039,0.00256422,0.999225 beta-lactamase_625_Y103G,beta-lactamase_625_103,TEM-1,beta-lactamase_625,P62593,0.999226,NO,103,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-1.33,-3.527,2.197,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.213352,0.00443048,0.999226 kka2_1:4_A166S,kka2_1:4_166,Kka2,kka2_1:4,P00552,0.999226,NO,166,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.407,-1.802,-0.605,,0.534,.,B,0.46,1.03,,,71.59,HHO,-2.421,0.168804,0.00799912,0.999226 beta-lactamase_A266G,beta-lactamase_266,TEM-1,beta-lactamase,P62593,0.999227,NO,266,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.369,-2.612,1.243,5.02057,0.175,S,B,0.52,0.07,1.832,,64.34,PHP,-2.08567,0.221079,0.0140785,0.999227 kka2_1:8_D238D,kka2_1:8_238,Kka2,kka2_1:8,P00552,0.999227,NO,238,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.83,-2.83,,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.100394,0.0113863,0.999227 kka2_1:8_D238D,kka2_1:8_238,Kka2,kka2_1:8,P00552,0.999227,NO,238,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.83,-2.83,,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.100394,0.0113863,0.999227 beta-lactamase_156_Q267T,beta-lactamase_156_267,TEM-1,beta-lactamase_156,P62593,0.999229,NO,267,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.308,-3.09,0.782,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.111618,0.0102128,0.999229 beta-lactamase_156_R91M,beta-lactamase_156_91,TEM-1,beta-lactamase_156,P62593,0.999236,NO,91,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.392,-4.593,3.201,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.111618,0.00380226,0.999236 beta-lactamase_39_P165S,beta-lactamase_39_165,TEM-1,beta-lactamase_39,P62593,0.999237,NO,165,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.373,-3.19,1.817,,0.203,T,A,0.52,-0.31,3.907,,73.78,AOA,-1.359,0.0495842,0.00549538,0.999237 beta-lactamase_625_A34L,beta-lactamase_625_34,TEM-1,beta-lactamase_625,P62593,0.999242,NO,34,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.059,-2.191,0.132,,,H,A,0.46,-0.54,3.614,,73.78,AHA,-1.74967,0.213352,0.00407913,0.999242 kka2_1:1_A13A,kka2_1:1_13,Kka2,kka2_1:1,P00552,0.999242,NO,13,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.248,-2.248,,,0.689,G,A,0.46,0.99,25.015,25.015,92.05,OHH,-1.646,0.520039,0.00784241,0.999242 kka2_1:1_Q42Q,kka2_1:1_42,Kka2,kka2_1:1,P00552,0.999242,NO,42,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.907,-2.907,,,1.044,T,B,0.4,-0.8,2.792,,71.59,HPO,-2.12433,0.520039,0.00679212,0.999242 beta-lactamase_39_T147W,beta-lactamase_39_147,TEM-1,beta-lactamase_39,P62593,0.999243,NO,147,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.149,-5.268,4.119,,0.281,H,A,0.22,-0.68,13.843,13.843,64.34,HPH,-1.456,0.0495842,0.00226017,0.999243 beta-lactamase_39_P165R,beta-lactamase_39_165,TEM-1,beta-lactamase_39,P62593,0.999245,NO,165,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.373,-3.877,2.504,,0.203,T,A,0.52,-0.31,3.907,,73.78,AOA,-1.359,0.0495842,0.00549538,0.999245 beta-lactamase_2500_H24R,beta-lactamase_2500_24,TEM-1,beta-lactamase_2500,P62593,0.999252,NO,24,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-2.481,-3.749,1.268,,,,,,,0.467,,93.01,OBO,-2.0035,0.361275,0.00238894,0.999252 beta-lactamase_156_S96N,beta-lactamase_156_96,TEM-1,beta-lactamase_156,P62593,0.999253,NO,96,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.27,-3.037,0.767,,0.368,,b,0.27,0.39,2.838,,73.78,HPP,-2.019,0.111618,0.00551835,0.999253 kka2_1:4_A108A,kka2_1:4_108,Kka2,kka2_1:4,P00552,0.999254,NO,108,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.061,-2.061,,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.168804,0.00751209,0.999254 kka2_1:4_T72T,kka2_1:4_72,Kka2,kka2_1:4,P00552,0.999258,NO,72,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.38,-2.38,,,0.784,H,A,0.82,0.29,6.463,,65.53,HPP,-2.238,0.168804,0.00750756,0.999258 beta-lactamase_625_S256V,beta-lactamase_625_256,TEM-1,beta-lactamase_625,P62593,0.999259,NO,256,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.213352,0.00710634,0.999259 kka2_1:1_A191F,kka2_1:1_191,Kka2,kka2_1:1,P00552,0.999259,NO,191,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.831,-4.183,3.352,,,.,b,0.46,-0.94,0.53,,50,AHO,-0.868667,0.520039,0.00338807,0.999259 kka2_1:1_A41C,kka2_1:1_41,Kka2,kka2_1:1,P00552,0.999259,NO,41,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.879,-3.65,1.771,,0.184,.,B,0.46,-0.96,18.207,18.207,64.39,PHP,-2.477,0.520039,0.00543332,0.999259 kka2_1:1_D52A,kka2_1:1_52,Kka2,kka2_1:1,P00552,0.999259,NO,52,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.271,-3.15,0.879,,0.22,E,B,0.75,0.8,2.64,,71.59,PAH,-2.38367,0.520039,0.00175694,0.999259 kka2_1:1_D52S,kka2_1:1_52,Kka2,kka2_1:1,P00552,0.999259,NO,52,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.271,-3.212,0.941,,0.22,E,B,0.75,0.8,2.64,,71.59,PAH,-2.38367,0.520039,0.00175694,0.999259 kka2_1:1_D5K,kka2_1:1_5,Kka2,kka2_1:1,P00552,0.999259,NO,5,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.306,-3.094,1.788,,,,,,,0.895,,71.59,PAO,-1.784,0.520039,0.00222864,0.999259 kka2_1:1_D5L,kka2_1:1_5,Kka2,kka2_1:1,P00552,0.999259,NO,5,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.306,-3.538,2.232,,,,,,,0.895,,71.59,PAO,-1.784,0.520039,0.00222864,0.999259 kka2_1:1_E3F,kka2_1:1_3,Kka2,kka2_1:1,P00552,0.999259,NO,3,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.199,-3.772,1.573,,,,,,,3.435,,92.05,HAP,-2.11567,0.520039,0.00267607,0.999259 kka2_1:1_E3R,kka2_1:1_3,Kka2,kka2_1:1,P00552,0.999259,NO,3,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.199,-3.722,1.523,,,,,,,3.435,,92.05,HAP,-2.11567,0.520039,0.00267607,0.999259 kka2_1:1_F256W,kka2_1:1_256,Kka2,kka2_1:1,P00552,0.999259,NO,256,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.49,-2.846,1.356,,,H,A,1.62,-0.78,2.354,,53.03,HHH,-1.423,0.520039,0.0132841,0.999259 kka2_1:1_G234K,kka2_1:1_234,Kka2,kka2_1:1,P00552,0.999259,NO,234,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-2.9,-2.482,-0.418,,0.494,H,A,0.29,-0.29,1.753,,71.59,OOA,-1.86767,0.520039,0.00984449,0.999259 kka2_1:1_G234P,kka2_1:1_234,Kka2,kka2_1:1,P00552,0.999259,NO,234,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-2.9,-2.731,-0.169,,0.494,H,A,0.29,-0.29,1.753,,71.59,OOA,-1.86767,0.520039,0.00984449,0.999259 kka2_1:1_G6A,kka2_1:1_6,Kka2,kka2_1:1,P00552,0.999259,NO,6,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.685,-2.835,1.15,,,,,,,1.292,,71.59,AOH,-1.639,0.520039,0.00204693,0.999259 kka2_1:1_G6F,kka2_1:1_6,Kka2,kka2_1:1,P00552,0.999259,NO,6,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.685,-4.169,2.484,,,,,,,1.292,,71.59,AOH,-1.639,0.520039,0.00204693,0.999259 kka2_1:1_G6K,kka2_1:1_6,Kka2,kka2_1:1,P00552,0.999259,NO,6,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.685,-2.23,0.545,,,,,,,1.292,,71.59,AOH,-1.639,0.520039,0.00204693,0.999259 kka2_1:1_G6M,kka2_1:1_6,Kka2,kka2_1:1,P00552,0.999259,NO,6,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.685,-4.549,2.864,,,,,,,1.292,,71.59,AOH,-1.639,0.520039,0.00204693,0.999259 kka2_1:1_G6N,kka2_1:1_6,Kka2,kka2_1:1,P00552,0.999259,NO,6,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.685,-3.547,1.862,,,,,,,1.292,,71.59,AOH,-1.639,0.520039,0.00204693,0.999259 kka2_1:1_G6P,kka2_1:1_6,Kka2,kka2_1:1,P00552,0.999259,NO,6,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.685,-2.187,0.502,,,,,,,1.292,,71.59,AOH,-1.639,0.520039,0.00204693,0.999259 kka2_1:1_G6S,kka2_1:1_6,Kka2,kka2_1:1,P00552,0.999259,NO,6,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.685,-3.143,1.458,,,,,,,1.292,,71.59,AOH,-1.639,0.520039,0.00204693,0.999259 kka2_1:1_G6T,kka2_1:1_6,Kka2,kka2_1:1,P00552,0.999259,NO,6,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.685,-3.379,1.694,,,,,,,1.292,,71.59,AOH,-1.639,0.520039,0.00204693,0.999259 kka2_1:1_G6W,kka2_1:1_6,Kka2,kka2_1:1,P00552,0.999259,NO,6,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.685,-5.12,3.435,,,,,,,1.292,,71.59,AOH,-1.639,0.520039,0.00204693,0.999259 kka2_1:1_G6Y,kka2_1:1_6,Kka2,kka2_1:1,P00552,0.999259,NO,6,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.685,-4.17,2.485,,,,,,,1.292,,71.59,AOH,-1.639,0.520039,0.00204693,0.999259 kka2_1:1_H106D,kka2_1:1_106,Kka2,kka2_1:1,P00552,0.999259,NO,106,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-3.13,-2.351,-0.779,,1.065,.,a,0.17,-0.95,2.53,,71.59,PBH,-2.10433,0.520039,0.00730778,0.999259 kka2_1:1_H162N,kka2_1:1_162,Kka2,kka2_1:1,P00552,0.999259,NO,162,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-2.319,-2.321,0.002,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.520039,0.00616145,0.999259 kka2_1:1_I221L,kka2_1:1_221,Kka2,kka2_1:1,P00552,0.999259,NO,221,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.739,-1.153,-0.586,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.520039,0.00945908,0.999259 kka2_1:1_I2F,kka2_1:1_2,Kka2,kka2_1:1,P00552,0.999259,NO,2,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.787,-3.633,1.846,,,,,,,2.329,,71.59,HHA,-1.92433,0.520039,0.00246644,0.999259 kka2_1:1_I2K,kka2_1:1_2,Kka2,kka2_1:1,P00552,0.999259,NO,2,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.787,-3.536,1.749,,,,,,,2.329,,71.59,HHA,-1.92433,0.520039,0.00246644,0.999259 kka2_1:1_L158F,kka2_1:1_158,Kka2,kka2_1:1,P00552,0.999259,NO,158,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.947,-1.154,-0.793,,0.095,.,B,0.55,0.77,7.588,,63.64,AHA,-1.25333,0.520039,0.00529068,0.999259 kka2_1:1_L53K,kka2_1:1_53,Kka2,kka2_1:1,P00552,0.999259,NO,53,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-2.681,-3.091,0.41,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.520039,0.00671168,0.999259 kka2_1:1_L7C,kka2_1:1_7,Kka2,kka2_1:1,P00552,0.999259,NO,7,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.926,-4.785,2.859,,,,,,,18.934,18.934,71.59,OHB,-2.12333,0.520039,0.00269456,0.999259 kka2_1:1_Q155E,kka2_1:1_155,Kka2,kka2_1:1,P00552,0.999259,NO,155,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.606,-1.223,-1.383,,0.525,T,A,0.4,1.49,4.415,,63.64,APA,-1.726,0.520039,0.00641853,0.999259 kka2_1:1_Q155V,kka2_1:1_155,Kka2,kka2_1:1,P00552,0.999259,NO,155,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.606,-2.82,0.214,,0.525,T,A,0.4,1.49,4.415,,63.64,APA,-1.726,0.520039,0.00641853,0.999259 kka2_1:1_Q155W,kka2_1:1_155,Kka2,kka2_1:1,P00552,0.999259,NO,155,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.606,-5.444,2.838,,0.525,T,A,0.4,1.49,4.415,,63.64,APA,-1.726,0.520039,0.00641853,0.999259 kka2_1:1_R177A,kka2_1:1_177,Kka2,kka2_1:1,P00552,0.999259,NO,177,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.282,-2.56,0.278,,0.521,T,A,1.2,0.16,1.842,,63.64,HBH,-2.36967,0.520039,0.00768224,0.999259 kka2_1:1_R177C,kka2_1:1_177,Kka2,kka2_1:1,P00552,0.999259,NO,177,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.282,-5.144,2.862,,0.521,T,A,1.2,0.16,1.842,,63.64,HBH,-2.36967,0.520039,0.00768224,0.999259 kka2_1:1_R177E,kka2_1:1_177,Kka2,kka2_1:1,P00552,0.999259,NO,177,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.282,-2.717,0.435,,0.521,T,A,1.2,0.16,1.842,,63.64,HBH,-2.36967,0.520039,0.00768224,0.999259 kka2_1:1_R177F,kka2_1:1_177,Kka2,kka2_1:1,P00552,0.999259,NO,177,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.282,-4.359,2.077,,0.521,T,A,1.2,0.16,1.842,,63.64,HBH,-2.36967,0.520039,0.00768224,0.999259 kka2_1:1_R177H,kka2_1:1_177,Kka2,kka2_1:1,P00552,0.999259,NO,177,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.282,-3.561,1.279,,0.521,T,A,1.2,0.16,1.842,,63.64,HBH,-2.36967,0.520039,0.00768224,0.999259 kka2_1:1_R177I,kka2_1:1_177,Kka2,kka2_1:1,P00552,0.999259,NO,177,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.282,-3.929,1.647,,0.521,T,A,1.2,0.16,1.842,,63.64,HBH,-2.36967,0.520039,0.00768224,0.999259 kka2_1:1_R177L,kka2_1:1_177,Kka2,kka2_1:1,P00552,0.999259,NO,177,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.282,-2.255,-0.027,,0.521,T,A,1.2,0.16,1.842,,63.64,HBH,-2.36967,0.520039,0.00768224,0.999259 kka2_1:1_R177M,kka2_1:1_177,Kka2,kka2_1:1,P00552,0.999259,NO,177,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.282,-3.296,1.014,,0.521,T,A,1.2,0.16,1.842,,63.64,HBH,-2.36967,0.520039,0.00768224,0.999259 kka2_1:1_R177N,kka2_1:1_177,Kka2,kka2_1:1,P00552,0.999259,NO,177,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.282,-2.629,0.347,,0.521,T,A,1.2,0.16,1.842,,63.64,HBH,-2.36967,0.520039,0.00768224,0.999259 kka2_1:1_R177Q,kka2_1:1_177,Kka2,kka2_1:1,P00552,0.999259,NO,177,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.282,-3.061,0.779,,0.521,T,A,1.2,0.16,1.842,,63.64,HBH,-2.36967,0.520039,0.00768224,0.999259 kka2_1:1_R177S,kka2_1:1_177,Kka2,kka2_1:1,P00552,0.999259,NO,177,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.282,-2.536,0.254,,0.521,T,A,1.2,0.16,1.842,,63.64,HBH,-2.36967,0.520039,0.00768224,0.999259 kka2_1:1_R177T,kka2_1:1_177,Kka2,kka2_1:1,P00552,0.999259,NO,177,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.282,-2.275,-0.007,,0.521,T,A,1.2,0.16,1.842,,63.64,HBH,-2.36967,0.520039,0.00768224,0.999259 kka2_1:1_R177W,kka2_1:1_177,Kka2,kka2_1:1,P00552,0.999259,NO,177,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.282,-5.514,3.232,,0.521,T,A,1.2,0.16,1.842,,63.64,HBH,-2.36967,0.520039,0.00768224,0.999259 kka2_1:1_S11C,kka2_1:1_11,Kka2,kka2_1:1,P00552,0.999259,NO,11,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.322,-4.711,2.389,,0.408,,B,0.77,1.64,2.054,,92.05,OPO,-1.69867,0.520039,0.00381691,0.999259 kka2_1:1_S11I,kka2_1:1_11,Kka2,kka2_1:1,P00552,0.999259,NO,11,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.322,-2.514,0.192,,0.408,,B,0.77,1.64,2.054,,92.05,OPO,-1.69867,0.520039,0.00381691,0.999259 kka2_1:1_S11L,kka2_1:1_11,Kka2,kka2_1:1,P00552,0.999259,NO,11,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.322,-1.799,-0.523,,0.408,,B,0.77,1.64,2.054,,92.05,OPO,-1.69867,0.520039,0.00381691,0.999259 kka2_1:1_S11M,kka2_1:1_11,Kka2,kka2_1:1,P00552,0.999259,NO,11,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.322,-2.896,0.574,,0.408,,B,0.77,1.64,2.054,,92.05,OPO,-1.69867,0.520039,0.00381691,0.999259 kka2_1:1_S11P,kka2_1:1_11,Kka2,kka2_1:1,P00552,0.999259,NO,11,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.322,-2.34,0.018,,0.408,,B,0.77,1.64,2.054,,92.05,OPO,-1.69867,0.520039,0.00381691,0.999259 kka2_1:1_S11Q,kka2_1:1_11,Kka2,kka2_1:1,P00552,0.999259,NO,11,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.322,-3.989,1.667,,0.408,,B,0.77,1.64,2.054,,92.05,OPO,-1.69867,0.520039,0.00381691,0.999259 kka2_1:1_S11Y,kka2_1:1_11,Kka2,kka2_1:1,P00552,0.999259,NO,11,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.322,-4.097,1.775,,0.408,,B,0.77,1.64,2.054,,92.05,OPO,-1.69867,0.520039,0.00381691,0.999259 kka2_1:1_T146I,kka2_1:1_146,Kka2,kka2_1:1,P00552,0.999259,NO,146,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.978,-3.15,0.172,,0.281,H,A,0.82,0.78,2.105,,92.05,BPB,-1.96833,0.520039,0.00606474,0.999259 kka2_1:1_V242K,kka2_1:1_242,Kka2,kka2_1:1,P00552,0.999259,NO,242,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-2.687,-2.489,-0.198,,0.75,H,A,0.44,-0.37,4.987,,71.59,HHH,-2.16533,0.520039,0.0102575,0.999259 kka2_1:1_V46T,kka2_1:1_46,Kka2,kka2_1:1,P00552,0.999259,NO,46,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-2.62,-2.441,-0.179,,0.192,.,B,0.44,-1.12,20.149,20.149,92.05,OHH,-1.88633,0.520039,0.00631301,0.999259 kka2_1:8_Q42Q,kka2_1:8_42,Kka2,kka2_1:8,P00552,0.99926,NO,42,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.907,-2.907,,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.100394,0.00679212,0.99926 kka2_1:8_Q42Q,kka2_1:8_42,Kka2,kka2_1:8,P00552,0.99926,NO,42,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.907,-2.907,,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.100394,0.00679212,0.99926 beta-lactamase_625_H151W,beta-lactamase_625_151,TEM-1,beta-lactamase_625,P62593,0.999263,NO,151,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-2.96,-5.334,2.374,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.213352,0.00216946,0.999263 beta-lactamase_625_D113F,beta-lactamase_625_113,TEM-1,beta-lactamase_625,P62593,0.999264,NO,113,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.829,-4.448,2.619,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.213352,0.00474112,0.999264 beta-lactamase_625_R275G,beta-lactamase_625_275,TEM-1,beta-lactamase_625,P62593,0.999265,NO,275,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.213352,0.0141984,0.999265 beta-lactamase_156_R176H,beta-lactamase_156_176,TEM-1,beta-lactamase_156,P62593,0.999267,NO,176,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-0.863,-4.23,3.367,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.111618,0.00105554,0.999267 PSD95pdz3_A370R,PSD95pdz3_370,PSD95pdz3,PSD95pdz3,P31016,0.999267,NO,370,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.307,-3.39,2.083,5.22304,,,,,17.284,,,,PHP,-1.57967,0.0758425,0.000429106,0.999267 PSD95pdz3_Q374P,PSD95pdz3_374,PSD95pdz3,PSD95pdz3,P31016,0.999268,NO,374,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-1.699,-3.336,1.637,5.38825,,,,,17.3289,,,,APH,-1.47,0.0758425,0.000372298,0.999268 beta-lactamase_156_P60S,beta-lactamase_156_60,TEM-1,beta-lactamase_156,P62593,0.99927,NO,60,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-2.469,-2.362,-0.107,,0.256,T,A,0.52,-0.56,2.947,,77.62,BOA,-1.97633,0.111618,0.00521318,0.99927 beta-lactamase_625_N50A,beta-lactamase_625_50,TEM-1,beta-lactamase_625,P62593,0.999272,NO,50,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-2.979,-1.868,-1.111,,0.912,T,A,0.61,1.24,3.446,,77.62,HPP,-2.134,0.213352,0.0047211,0.999272 kka2_1:4_A150A,kka2_1:4_150,Kka2,kka2_1:4,P00552,0.999272,NO,150,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.949,-0.949,,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.168804,0.0045009,0.999272 beta-lactamase_39_G114F,beta-lactamase_39_114,TEM-1,beta-lactamase_39,P62593,0.999275,NO,114,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.094,-4.331,3.237,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.0495842,0.00224919,0.999275 kka2_1:4_L47L,kka2_1:4_47,Kka2,kka2_1:4,P00552,0.999276,NO,47,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.265,-1.265,,,0.139,E,B,0.55,-0.86,2.369,,63.26,HHH,-1.77933,0.168804,0.00509386,0.999276 kka2_1:4_T28T,kka2_1:4_28,Kka2,kka2_1:4,P00552,0.999276,NO,28,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.883,-1.883,,,0.353,S,B,0.82,2.02,4.415,,63.64,PPH,-1.74467,0.168804,0.00743084,0.999276 kka2_1:4_V80V,kka2_1:4_80,Kka2,kka2_1:4,P00552,0.999276,NO,80,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.144,-1.144,,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.168804,0.00488211,0.999276 kka2_1:8_E3E,kka2_1:8_3,Kka2,kka2_1:8,P00552,0.999276,NO,3,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.199,-2.199,,,,,,,,7.22,,92.05,HAP,-2.11567,0.100394,0.00267607,0.999276 kka2_1:8_E3E,kka2_1:8_3,Kka2,kka2_1:8,P00552,0.999276,NO,3,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.199,-2.199,,,,,,,,7.22,,92.05,HAP,-2.11567,0.100394,0.00267607,0.999276 beta-lactamase_39_S51Y,beta-lactamase_39_51,TEM-1,beta-lactamase_39,P62593,0.999277,NO,51,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.526,-4.345,2.819,,0.496,T,A,0.27,0.26,2.964,,72.73,PPO,-1.88467,0.0495842,0.00504821,0.999277 beta-lactamase_625_A211Q,beta-lactamase_625_211,TEM-1,beta-lactamase_625,P62593,0.999279,NO,211,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.896,-3.096,1.2,,0.369,T,A,0.46,-0.69,2.061,,77.62,AHA,-1.94633,0.213352,0.00648183,0.999279 beta-lactamase_625_E169K,beta-lactamase_625_169,TEM-1,beta-lactamase_625,P62593,0.999279,NO,169,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.23,-3.226,1.996,,0.337,,A,1.04,1,1.806,,73.08,PAH,-1.16533,0.213352,0.00400994,0.999279 beta-lactamase_625_P250A,beta-lactamase_625_250,TEM-1,beta-lactamase_625,P62593,0.999279,NO,250,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.213352,0.00550899,0.999279 kka2_1:2_L47L,kka2_1:2_47,Kka2,kka2_1:2,P00552,0.999279,NO,47,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.265,-1.265,,,0.139,E,B,0.55,-0.86,2.369,,63.26,HHH,-1.77933,0.295029,0.00509386,0.999279 beta-lactamase_2500_T269P,beta-lactamase_2500_269,TEM-1,beta-lactamase_2500,P62593,0.999282,NO,269,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.361275,0.00950944,0.999282 beta-lactamase_39_A247V,beta-lactamase_39_247,TEM-1,beta-lactamase_39,P62593,0.999282,NO,247,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.0495842,0.00611275,0.999282 beta-lactamase_39_L135S,beta-lactamase_39_135,TEM-1,beta-lactamase_39,P62593,0.999284,NO,135,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.002,-3.64,2.638,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.0495842,0.00244423,0.999284 beta-lactamase_39_N152H,beta-lactamase_39_152,TEM-1,beta-lactamase_39,P62593,0.999287,NO,152,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-2.757,-3.372,0.615,,0.863,H,A,0.61,0.92,4.038,,77.62,BPH,-2.97,0.0495842,0.00471429,0.999287 beta-lactamase_0_S68A,beta-lactamase_0_68,TEM-1,beta-lactamase_0,P62593,0.999289,NO,68,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-0.913,-2.711,1.798,,0.064,G,A,0.27,-1.03,1.441,,64.69,HPP,-1.37233,0.0500837,0.000800065,0.999289 beta-lactamase_156_T147V,beta-lactamase_156_147,TEM-1,beta-lactamase_156,P62593,0.999289,NO,147,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.149,-3.22,2.071,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.111618,0.00226017,0.999289 beta-lactamase_39_Q88F,beta-lactamase_39_88,TEM-1,beta-lactamase_39,P62593,0.999291,NO,88,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.086,-4.377,2.291,,0.807,,B,0.64,2.03,11.108,11.108,77.62,APH,-1.53433,0.0495842,0.00504167,0.999291 beta-lactamase_156_T126R,beta-lactamase_156_126,TEM-1,beta-lactamase_156,P62593,0.999292,NO,126,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.122,-3.84,2.718,,0.05,H,A,0.22,-0.05,1.14,,44.41,HPH,-1.60467,0.111618,0.00244552,0.999292 kka2_1:8_A87P,kka2_1:8_87,Kka2,kka2_1:8,P00552,0.999293,NO,87,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.917,-2.939,1.022,,1.039,S,L,0.46,1.57,16.115,16.115,65.53,AHO,-1.822,0.100394,0.00791281,0.999293 kka2_1:8_A87P,kka2_1:8_87,Kka2,kka2_1:8,P00552,0.999293,NO,87,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.917,-2.939,1.022,,1.039,S,L,0.46,1.57,16.115,16.115,65.53,AHO,-1.822,0.100394,0.00791281,0.999293 kka2_1:8_S40S,kka2_1:8_40,Kka2,kka2_1:8,P00552,0.999293,NO,40,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.645,-2.645,,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.100394,0.00693477,0.999293 kka2_1:8_S40S,kka2_1:8_40,Kka2,kka2_1:8,P00552,0.999293,NO,40,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.645,-2.645,,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.100394,0.00693477,0.999293 kka2_1:4_A110A,kka2_1:4_110,Kka2,kka2_1:4,P00552,0.999297,NO,110,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.064,-2.064,,,0.175,H,A,0.46,-1.19,23.237,23.237,71.59,OHA,-1.91867,0.168804,0.00759851,0.999297 kka2_1:4_A255A,kka2_1:4_255,Kka2,kka2_1:4,P00552,0.999297,NO,255,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.715,-1.715,,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.168804,0.0126809,0.999297 kka2_1:4_C31C,kka2_1:4_31,Kka2,kka2_1:4,P00552,0.999297,NO,31,C,C,CC,Special,Special,5.07,5.07,0,0,121,121,0,108.5,108.5,0,-2.246,-2.246,,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.168804,0.00681582,0.999297 beta-lactamase_156_V31L,beta-lactamase_156_31,TEM-1,beta-lactamase_156,P62593,0.999298,NO,31,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.822,-2.16,0.338,,,H,A,0.44,-0.46,4.126,,73.78,BHB,-2.03767,0.111618,0.00478065,0.999298 beta-lactamase_2500_S96K,beta-lactamase_2500_96,TEM-1,beta-lactamase_2500,P62593,0.999301,NO,96,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.27,-2.895,0.625,,0.368,,b,0.27,0.39,32.348,32.348,73.78,HPP,-2.019,0.361275,0.00551835,0.999301 kka2_1:2_P249P,kka2_1:2_249,Kka2,kka2_1:2,P00552,0.999304,NO,249,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.867,-1.867,,,0.406,.,B,0.52,-0.01,0.76,,92.05,HOA,-1.66867,0.295029,0.011045,0.999304 kka2_1:8_E235E,kka2_1:8_235,Kka2,kka2_1:8,P00552,0.999309,NO,235,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.955,-1.955,,,0.631,H,A,1.52,0.12,,,65.53,OAH,-2.07267,0.100394,0.0102806,0.999309 kka2_1:8_E235E,kka2_1:8_235,Kka2,kka2_1:8,P00552,0.999309,NO,235,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.955,-1.955,,,0.631,H,A,1.52,0.12,,,65.53,OAH,-2.07267,0.100394,0.0102806,0.999309 beta-lactamase_39_V78Y,beta-lactamase_39_78,TEM-1,beta-lactamase_39,P62593,0.999311,NO,78,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.459,-4.112,2.653,,,H,A,0.44,-0.47,1.132,,63.64,HHH,-1.17833,0.0495842,0.00492501,0.999311 kka2_1:4_I246I,kka2_1:4_246,Kka2,kka2_1:4,P00552,0.999312,NO,246,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-2.008,-2.008,,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.168804,0.0139479,0.999312 beta-lactamase_39_N173P,beta-lactamase_39_173,TEM-1,beta-lactamase_39,P62593,0.999313,NO,173,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-2.663,-3.891,1.228,,1.044,T,l,0.61,1.25,1.426,,77.62,OPA,-1.46633,0.0495842,0.0033769,0.999313 beta-lactamase_39_Q204P,beta-lactamase_39_204,TEM-1,beta-lactamase_39,P62593,0.999313,NO,204,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-1.382,-3.857,2.475,,0.204,H,A,0.64,0.09,0.489,,66.08,PPH,-1.49067,0.0495842,0.00364106,0.999313 beta-lactamase_39_T263G,beta-lactamase_39_263,TEM-1,beta-lactamase_39,P62593,0.999313,NO,263,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.031,-3.618,1.587,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.0495842,0.0110582,0.999313 kka2_1:2_L243L,kka2_1:2_243,Kka2,kka2_1:2,P00552,0.999313,NO,243,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-2.651,-2.651,,,0.277,H,A,1.59,-0.67,13.165,13.165,92.05,HHH,-2.03767,0.295029,0.00884927,0.999313 beta-lactamase_P12A,beta-lactamase_12,TEM-1,beta-lactamase,P62593,0.999314,NO,12,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-2.016,-2.206,0.19,,,,,,,2.88,,72.73,HOH,-2.05167,0.221079,0.00241653,0.999314 beta-lactamase_156_G52N,beta-lactamase_156_52,TEM-1,beta-lactamase_156,P62593,0.999315,NO,52,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.149,-3.58,2.431,,0.299,,l,0.29,-0.04,1.179,,64.69,POB,-1.66267,0.111618,0.00340138,0.999315 kka2_1:4_G21G,kka2_1:4_21,Kka2,kka2_1:4,P00552,0.999315,NO,21,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.368,-1.368,,,0.586,T,l,0.75,-0.75,3.075,,71.59,HOH,-2.10167,0.168804,0.00709648,0.999315 kka2_1:2_V84V,kka2_1:2_84,Kka2,kka2_1:2,P00552,0.999316,NO,84,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-2.279,-2.279,,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.295029,0.00724019,0.999316 kka2_1:2_E63L,kka2_1:2_63,Kka2,kka2_1:2,P00552,0.999317,NO,63,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-0.762,-3.611,2.849,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.295029,0.00118399,0.999317 kka2_1:4_V84V,kka2_1:4_84,Kka2,kka2_1:4,P00552,0.999319,NO,84,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-2.279,-2.279,,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.168804,0.00724019,0.999319 beta-lactamase_625_T116A,beta-lactamase_625_116,TEM-1,beta-lactamase_625,P62593,0.999321,NO,116,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.28,-2.469,1.189,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.213352,0.00336175,0.999321 kka2_1:2_T28T,kka2_1:2_28,Kka2,kka2_1:2,P00552,0.999323,NO,28,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.883,-1.883,,,0.353,S,B,0.22,2.02,2.655,,63.64,PPH,-1.74467,0.295029,0.00743084,0.999323 kka2_1:8_F20F,kka2_1:8_20,Kka2,kka2_1:8,P00552,0.999326,NO,20,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-3.354,-3.354,,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.100394,0.00701744,0.999326 kka2_1:8_F20F,kka2_1:8_20,Kka2,kka2_1:8,P00552,0.999326,NO,20,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-3.354,-3.354,,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.100394,0.00701744,0.999326 kka2_1:8_P249P,kka2_1:8_249,Kka2,kka2_1:8,P00552,0.999326,NO,249,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.867,-1.867,,,0.406,.,B,0.52,-0.01,1.699,,92.05,HOA,-1.66867,0.100394,0.011045,0.999326 kka2_1:8_P249P,kka2_1:8_249,Kka2,kka2_1:8,P00552,0.999326,NO,249,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.867,-1.867,,,0.406,.,B,0.52,-0.01,1.699,,92.05,HOA,-1.66867,0.100394,0.011045,0.999326 kka2_1:4_D156D,kka2_1:4_156,Kka2,kka2_1:4,P00552,0.99933,NO,156,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.696,-1.696,,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.168804,0.00926998,0.99933 beta-lactamase_39_E272G,beta-lactamase_39_272,TEM-1,beta-lactamase_39,P62593,0.999333,NO,272,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.127,,,,0.081,H,A,0.43,-0.97,12.983,12.983,63.64,AAB,-1.56333,0.0495842,0.00545371,0.999333 beta-lactamase_156_M180T,beta-lactamase_156_180,TEM-1,beta-lactamase_156,P62593,0.999335,NO,180,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-2.795,-1.278,-1.517,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.111618,0.00552048,0.999335 kka2_1:4_D154D,kka2_1:4_154,Kka2,kka2_1:4,P00552,0.999335,NO,154,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.876,-0.876,,,0.457,,b,0.29,1.48,15.641,15.641,52.65,HAP,-1.52467,0.168804,0.00292633,0.999335 beta-lactamase_625_R41N,beta-lactamase_625_41,TEM-1,beta-lactamase_625,P62593,0.999336,NO,41,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-0.942,-3.445,2.503,,0.321,E,B,1.2,-0.07,1.186,,65.03,HBH,-1.30267,0.213352,0.00123327,0.999336 beta-lactamase_625_E175M,beta-lactamase_625_175,TEM-1,beta-lactamase_625,P62593,0.999339,NO,175,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.336,-3.397,1.061,,0.551,,A,1.04,1.05,8.527,8.527,77.62,AAB,-1.31233,0.213352,0.00482205,0.999339 beta-lactamase_2500_Q86V,beta-lactamase_2500_86,TEM-1,beta-lactamase_2500,P62593,0.99934,NO,86,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.4,-2.988,0.588,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.361275,0.00450027,0.99934 kka2_1:8_E160E,kka2_1:8_160,Kka2,kka2_1:8,P00552,0.999342,NO,160,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.683,-1.683,,,0.989,G,A,1.04,2.28,2.164,,71.59,AAA,-1.36133,0.100394,0.00935762,0.999342 kka2_1:8_E160E,kka2_1:8_160,Kka2,kka2_1:8,P00552,0.999342,NO,160,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.683,-1.683,,,0.989,G,A,1.04,2.28,2.164,,71.59,AAA,-1.36133,0.100394,0.00935762,0.999342 beta-lactamase_156_T139R,beta-lactamase_156_139,TEM-1,beta-lactamase_156,P62593,0.999343,NO,139,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.901,-2.238,0.337,,0.216,H,A,0.22,0.39,16.34,16.34,77.62,PPH,-2.04667,0.111618,0.00441837,0.999343 beta-lactamase_39_L197C,beta-lactamase_39_197,TEM-1,beta-lactamase_39,P62593,0.999343,NO,197,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.853,-4.635,3.782,,0.007,S,B,0.55,0.33,1.559,,60.14,HHP,-1.833,0.0495842,0.00144602,0.999343 kka2_1:4_Q136Q,kka2_1:4_136,Kka2,kka2_1:4,P00552,0.999348,NO,136,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-3.021,-3.021,,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.168804,0.00624149,0.999348 beta-lactamase_625_E56V,beta-lactamase_625_56,TEM-1,beta-lactamase_625,P62593,0.999349,NO,56,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.043,-3.397,1.354,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.213352,0.00238534,0.999349 beta-lactamase_39_P250M,beta-lactamase_39_250,TEM-1,beta-lactamase_39,P62593,0.999351,NO,250,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.0495842,0.00550899,0.999351 kka2_1:2_M1M,kka2_1:2_1,Kka2,kka2_1:2,P00552,0.999351,NO,1,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.787,-1.787,,,,,,,,1.347,,62.12,NAHH,-1.787,0.295029,0.00251939,0.999351 kka2_1:4_P167P,kka2_1:4_167,Kka2,kka2_1:4,P00552,0.999351,NO,167,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-2.403,-2.403,,,0.18,H,A,0.52,0.75,3.6,,64.39,HOH,-2.26633,0.168804,0.00543203,0.999351 beta-lactamase_39_Q276S,beta-lactamase_39_276,TEM-1,beta-lactamase_39,P62593,0.999353,NO,276,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.0495842,0.0191712,0.999353 beta-lactamase_39_G76A,beta-lactamase_39_76,TEM-1,beta-lactamase_39,P62593,0.999354,NO,76,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.189,-1.531,0.342,,,H,A,0.29,-0.67,2.145,,67.83,OOH,-1.22267,0.0495842,0.00476637,0.999354 beta-lactamase_625_A222W,beta-lactamase_625_222,TEM-1,beta-lactamase_625,P62593,0.999354,NO,222,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.103,-5.409,3.306,,0.233,H,A,0.46,-0.25,1.448,,77.62,PHH,-1.63733,0.213352,0.00466094,0.999354 beta-lactamase_156_Y103P,beta-lactamase_156_103,TEM-1,beta-lactamase_156,P62593,0.999355,NO,103,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-1.33,-4.138,2.808,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.111618,0.00443048,0.999355 beta-lactamase_625_K32L,beta-lactamase_625_32,TEM-1,beta-lactamase_625,P62593,0.999355,NO,32,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.984,-2.812,0.828,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.213352,0.00401283,0.999355 beta-lactamase_0_L111V,beta-lactamase_0_111,TEM-1,beta-lactamase_0,P62593,0.999356,NO,111,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.76,-1.731,-0.029,,0.328,T,A,0.55,0.93,1.966,,64.34,BHP,-1.884,0.0500837,0.00480671,0.999356 beta-lactamase_625_A185C,beta-lactamase_625_185,TEM-1,beta-lactamase_625,P62593,0.999357,NO,185,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.406,-4.699,3.293,,,H,A,0.46,-1.02,0.365,,65.03,HHP,-1.84033,0.213352,0.00467449,0.999357 kka2_1:4_D33D,kka2_1:4_33,Kka2,kka2_1:4,P00552,0.999358,NO,33,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.186,-2.186,,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.168804,0.00633568,0.999358 kka2_1:8_E231E,kka2_1:8_231,Kka2,kka2_1:8,P00552,0.999359,NO,231,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.002,-2.002,,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.100394,0.00732383,0.999359 kka2_1:8_E231E,kka2_1:8_231,Kka2,kka2_1:8,P00552,0.999359,NO,231,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.002,-2.002,,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.100394,0.00732383,0.999359 kka2_1:8_V80V,kka2_1:8_80,Kka2,kka2_1:8,P00552,0.999359,NO,80,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.144,-1.144,,,0.358,E,B,1.48,-0.24,2.562,,63.64,HHH,-1.64633,0.100394,0.00488211,0.999359 kka2_1:8_V80V,kka2_1:8_80,Kka2,kka2_1:8,P00552,0.999359,NO,80,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.144,-1.144,,,0.358,E,B,1.48,-0.24,2.562,,63.64,HHH,-1.64633,0.100394,0.00488211,0.999359 beta-lactamase_625_S283C,beta-lactamase_625_283,TEM-1,beta-lactamase_625,P62593,0.999365,NO,283,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.213352,0.0429138,0.999365 kka2_1:2_Q136Q,kka2_1:2_136,Kka2,kka2_1:2,P00552,0.999367,NO,136,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-3.021,-3.021,,,0.331,,b,0.4,0.96,2.726,,92.05,BPH,-2.16933,0.295029,0.00624149,0.999367 beta-lactamase_A148H,beta-lactamase_148,TEM-1,beta-lactamase,P62593,0.999368,NO,148,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.757,-3.344,1.587,5.28111,0.379,H,A,0.52,-0.55,2.117,,72.73,PHH,-1.40167,0.221079,0.00547053,0.999368 beta-lactamase_A225Y,beta-lactamase_225,TEM-1,beta-lactamase,P62593,0.999368,NO,225,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.845,-4.327,2.482,6.5181,1,T,B,0.58,-0.38,4.077,,74.48,OHO,-1.39967,0.221079,0.00465057,0.999368 beta-lactamase_D155D,beta-lactamase_155,TEM-1,beta-lactamase,P62593,0.999368,NO,155,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.889,-0.889,,4.92265,0.049,,B,0.45,-0.9,3.208,,64.69,OAB,-1.62267,0.221079,0.00135315,0.999368 beta-lactamase_E175N,beta-lactamase_175,TEM-1,beta-lactamase,P62593,0.999368,NO,175,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.336,-3.857,1.521,6.0311,0.551,,A,0.75,1.05,5.316,,77.62,AAB,-1.31233,0.221079,0.00482205,0.999368 beta-lactamase_K109L,beta-lactamase_109,TEM-1,beta-lactamase,P62593,0.999368,NO,109,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.734,-2.969,1.235,6.05842,0.787,G,A,1.82,2.21,21.623,21.623,72.73,ABB,-1.63333,0.221079,0.00462493,0.999368 beta-lactamase_K190H,beta-lactamase_190,TEM-1,beta-lactamase,P62593,0.999368,NO,190,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.994,-3.068,1.074,5.49163,0.371,H,A,1.82,0.16,29.753,29.753,77.62,BBH,-1.64167,0.221079,0.00574527,0.999368 beta-lactamase_Q4S,beta-lactamase_4,TEM-1,beta-lactamase,P62593,0.999368,NO,4,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,,-2.445,-0.119,,,,,,,,,,HPB,,0.221079,0.00316562,0.999368 beta-lactamase_V72P,beta-lactamase_72,TEM-1,beta-lactamase,P62593,0.999368,NO,72,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.658,-2.442,0.784,5.80324,,H,A,2.78,-1.03,2.964,,65.73,BHH,-1.32167,0.221079,0.00501194,0.999368 beta-lactamase_156_R273T,beta-lactamase_156_273,TEM-1,beta-lactamase_156,P62593,0.99937,NO,273,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.314,-3.558,1.244,,0.564,H,A,1.2,1.57,20.248,20.248,73.78,ABP,-1.841,0.111618,0.0077952,0.99937 beta-lactamase_156_T187V,beta-lactamase_156_187,TEM-1,beta-lactamase_156,P62593,0.999374,NO,187,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.401,-3.287,1.886,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.111618,0.00491782,0.999374 kka2_1:8_T146T,kka2_1:8_146,Kka2,kka2_1:8,P00552,0.999375,NO,146,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.978,-2.978,,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.100394,0.00606474,0.999375 kka2_1:8_T146T,kka2_1:8_146,Kka2,kka2_1:8,P00552,0.999375,NO,146,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.978,-2.978,,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.100394,0.00606474,0.999375 kka2_1:8_V75V,kka2_1:8_75,Kka2,kka2_1:8,P00552,0.999375,NO,75,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-2.06,-2.06,,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.100394,0.00693733,0.999375 kka2_1:8_V75V,kka2_1:8_75,Kka2,kka2_1:8,P00552,0.999375,NO,75,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-2.06,-2.06,,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.100394,0.00693733,0.999375 kka2_1:1_A137A,kka2_1:1_137,Kka2,kka2_1:1,P00552,0.999387,NO,137,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.156,-2.156,,,0.029,H,A,0.46,0.34,1.323,,63.26,PHB,-2.559,0.520039,0.00515054,0.999387 kka2_1:1_A25A,kka2_1:1_25,Kka2,kka2_1:1,P00552,0.999387,NO,25,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.496,-2.496,,,0.427,E,B,0.46,-0.47,6.872,6.872,65.53,HHP,-2.15167,0.520039,0.00595636,0.999387 beta-lactamase_0_A246S,beta-lactamase_0_246,TEM-1,beta-lactamase_0,P62593,0.999388,NO,246,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.121,-3.607,1.486,,0.01,E,B,0.46,-1.01,1.201,,73.78,HHH,-1.55633,0.0500837,0.00569458,0.999388 beta-lactamase_39_Q276M,beta-lactamase_39_276,TEM-1,beta-lactamase_39,P62593,0.999388,NO,276,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.0495842,0.0191712,0.999388 beta-lactamase_156_I54E,beta-lactamase_156_54,TEM-1,beta-lactamase_156,P62593,0.999389,NO,54,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-2.838,-2.58,-0.258,,0.669,E,B,0.48,-0.14,0.541,,73.78,BHH,-2.337,0.111618,0.00403589,0.999389 beta-lactamase_625_E102A,beta-lactamase_625_102,TEM-1,beta-lactamase_625,P62593,0.999391,NO,102,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.118,-2.327,0.209,,0.722,S,B,1.04,1.82,1.336,,73.08,HAH,-1.581,0.213352,0.00486633,0.999391 beta-lactamase_156_R220K,beta-lactamase_156_220,TEM-1,beta-lactamase_156,P62593,0.999393,NO,220,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-0.942,-2.865,1.923,,0.295,I,A,1.2,-0.76,2.164,,74.48,HBP,-1.33633,0.111618,0.00232421,0.999393 kka2_1:1_A248A,kka2_1:1_248,Kka2,kka2_1:1,P00552,0.999393,NO,248,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.124,-2.124,,,0.825,S,b,0.46,0.46,24.72,24.72,92.05,HHO,-2.15,0.520039,0.0125484,0.999393 kka2_1:4_Q27Q,kka2_1:4_27,Kka2,kka2_1:4,P00552,0.999394,NO,27,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-1.659,-1.659,,,0.608,,A,0.4,0.71,1.498,,65.53,PPP,-1.90733,0.168804,0.00595365,0.999394 kka2_1:1_D23D,kka2_1:1_23,Kka2,kka2_1:1,P00552,0.999396,NO,23,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.459,-2.459,,,0.695,E,B,0.75,-0.65,2.655,,65.53,HAH,-1.94033,0.520039,0.007195,0.999396 beta-lactamase_39_L192I,beta-lactamase_39_192,TEM-1,beta-lactamase_39,P62593,0.999398,NO,192,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.254,-2.519,1.265,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.0495842,0.00558728,0.999398 kka2_1:2_A110A,kka2_1:2_110,Kka2,kka2_1:2,P00552,0.999398,NO,110,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.064,-2.064,,,0.175,H,A,0.46,-1.19,23.237,23.237,71.59,OHA,-1.91867,0.295029,0.00759851,0.999398 beta-lactamase_39_Q204H,beta-lactamase_39_204,TEM-1,beta-lactamase_39,P62593,0.999401,NO,204,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-1.382,-3.09,1.708,,0.204,H,A,0.64,0.09,0.489,,66.08,PPH,-1.49067,0.0495842,0.00364106,0.999401 kka2_1:1_T125T,kka2_1:1_125,Kka2,kka2_1:1,P00552,0.999402,NO,125,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.622,-2.622,,,0.791,T,A,0.22,0.33,1.972,,92.05,BPH,-1.56933,0.520039,0.00821755,0.999402 beta-lactamase_625_L100V,beta-lactamase_625_100,TEM-1,beta-lactamase_625,P62593,0.999406,NO,100,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.218,-2.049,0.831,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.213352,0.00413885,0.999406 kka2_1:8_E149E,kka2_1:8_149,Kka2,kka2_1:8,P00552,0.999408,NO,149,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.994,-1.994,,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.100394,0.00803343,0.999408 kka2_1:8_E149E,kka2_1:8_149,Kka2,kka2_1:8,P00552,0.999408,NO,149,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.994,-1.994,,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.100394,0.00803343,0.999408 kka2_1:8_E199E,kka2_1:8_199,Kka2,kka2_1:8,P00552,0.999408,NO,199,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.234,-2.234,,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.100394,0.00854122,0.999408 kka2_1:8_E199E,kka2_1:8_199,Kka2,kka2_1:8,P00552,0.999408,NO,199,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.234,-2.234,,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.100394,0.00854122,0.999408 kka2_1:8_Q163Q,kka2_1:8_163,Kka2,kka2_1:8,P00552,0.999408,NO,163,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.162,-2.162,,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.100394,0.00719507,0.999408 kka2_1:8_Q163Q,kka2_1:8_163,Kka2,kka2_1:8,P00552,0.999408,NO,163,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.162,-2.162,,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.100394,0.00719507,0.999408 PSD95pdz3_S361G,PSD95pdz3_361,PSD95pdz3,PSD95pdz3,P31016,0.99941,NO,361,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.519,-2.59,1.071,4.8722,,,,,16.4533,,,,HPH,-1.47167,0.0758425,0.00055296,0.99941 beta-lactamase_I259V,beta-lactamase_259,TEM-1,beta-lactamase,P62593,0.999415,NO,259,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.522,-1.739,0.217,5.28457,,E,B,1,-0.8,1.24,,64.34,HHH,-1.53267,0.221079,0.0070773,0.999415 kka2_1:4_I254I,kka2_1:4_254,Kka2,kka2_1:4,P00552,0.999416,NO,254,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.933,-1.933,,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.168804,0.0132375,0.999416 kka2_1:4_L243L,kka2_1:4_243,Kka2,kka2_1:4,P00552,0.999416,NO,243,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-2.651,-2.651,,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.168804,0.00884927,0.999416 beta-lactamase_156_I45S,beta-lactamase_156_45,TEM-1,beta-lactamase_156,P62593,0.999417,NO,45,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-2.421,-2.717,0.296,,,E,B,0.48,-0.3,2.256,,77.62,HHA,-2.30267,0.111618,0.00452842,0.999417 beta-lactamase_156_R275E,beta-lactamase_156_275,TEM-1,beta-lactamase_156,P62593,0.999422,NO,275,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.111618,0.0141984,0.999422 kka2_1:8_A168A,kka2_1:8_168,Kka2,kka2_1:8,P00552,0.999425,NO,168,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.989,-1.989,,,0.67,H,A,0.46,0.15,11.329,11.329,64.39,OHA,-2.12933,0.100394,0.00806773,0.999425 kka2_1:8_A168A,kka2_1:8_168,Kka2,kka2_1:8,P00552,0.999425,NO,168,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.989,-1.989,,,0.67,H,A,0.46,0.15,11.329,11.329,64.39,OHA,-2.12933,0.100394,0.00806773,0.999425 kka2_1:8_D23D,kka2_1:8_23,Kka2,kka2_1:8,P00552,0.999425,NO,23,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.459,-2.459,,,0.695,E,B,0.75,-0.65,,,65.53,HAH,-1.94033,0.100394,0.007195,0.999425 kka2_1:8_D23D,kka2_1:8_23,Kka2,kka2_1:8,P00552,0.999425,NO,23,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.459,-2.459,,,0.695,E,B,0.75,-0.65,,,65.53,HAH,-1.94033,0.100394,0.007195,0.999425 kka2_1:8_H139H,kka2_1:8_139,Kka2,kka2_1:8,P00552,0.999425,NO,139,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-2.809,-2.809,,,0.471,H,A,0.17,0.68,28.583,28.583,63.64,BBB,-2.22,0.100394,0.00734779,0.999425 kka2_1:8_H139H,kka2_1:8_139,Kka2,kka2_1:8,P00552,0.999425,NO,139,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-2.809,-2.809,,,0.471,H,A,0.17,0.68,28.583,28.583,63.64,BBB,-2.22,0.100394,0.00734779,0.999425 kka2_1:8_Q155Q,kka2_1:8_155,Kka2,kka2_1:8,P00552,0.999425,NO,155,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.606,-2.606,,,0.525,T,A,0.64,1.49,,,63.64,APA,-1.726,0.100394,0.00641853,0.999425 kka2_1:8_Q155Q,kka2_1:8_155,Kka2,kka2_1:8,P00552,0.999425,NO,155,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.606,-2.606,,,0.525,T,A,0.64,1.49,,,63.64,APA,-1.726,0.100394,0.00641853,0.999425 beta-lactamase_2500_S283H,beta-lactamase_2500_283,TEM-1,beta-lactamase_2500,P62593,0.999427,NO,283,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.361275,0.0429138,0.999427 kka2_1:2_G55G,kka2_1:2_55,Kka2,kka2_1:2,P00552,0.999427,NO,55,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.625,-1.625,,,0.517,S,b,0.75,1.19,15.753,15.753,63.64,POH,-2.05967,0.295029,0.00667877,0.999427 beta-lactamase_39_R275N,beta-lactamase_39_275,TEM-1,beta-lactamase_39,P62593,0.99943,NO,275,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.0495842,0.0141984,0.99943 beta-lactamase_39_N50D,beta-lactamase_39_50,TEM-1,beta-lactamase_39,P62593,0.999431,NO,50,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-2.979,-2.468,-0.511,,0.912,T,A,0.61,1.24,10.736,,77.62,HPP,-2.134,0.0495842,0.0047211,0.999431 kka2_1:4_A71A,kka2_1:4_71,Kka2,kka2_1:4,P00552,0.999434,NO,71,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.824,-1.824,,,0.553,H,A,0.46,0.08,5.76,,64.39,HHP,-1.74033,0.168804,0.00727707,0.999434 beta-lactamase_0_F149I,beta-lactamase_0_149,TEM-1,beta-lactamase_0,P62593,0.999436,NO,149,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.299,-3.576,2.277,,0.195,H,A,0.58,0.11,3.518,,63.99,HHH,-1.46067,0.0500837,0.00418462,0.999436 beta-lactamase_39_G234A,beta-lactamase_39_234,TEM-1,beta-lactamase_39,P62593,0.999436,NO,234,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.62,-2.853,2.233,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.0495842,0.000889577,0.999436 Pab1_E175D,Pab1_175,Pab1,Pab1,P04147,0.999437,NO,175,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.055,-2.202,0.147,,,,,,,,,,AAA,-1.82667,0.175299,0.00203137,0.999437 kka2_1:2_A255A,kka2_1:2_255,Kka2,kka2_1:2,P00552,0.999439,NO,255,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.715,-1.715,,,0.466,H,A,0.46,-0.52,5.144,,65.53,HHH,-1.71267,0.295029,0.0126809,0.999439 beta-lactamase_0_H94V,beta-lactamase_0_94,TEM-1,beta-lactamase_0,P62593,0.99944,NO,94,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-2.5,-2.751,0.251,,0.776,,B,0.17,1.24,1.176,,77.62,HBH,-1.872,0.0500837,0.00389226,0.99944 kka2_1:8_D5D,kka2_1:8_5,Kka2,kka2_1:8,P00552,0.999441,NO,5,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.306,-1.306,,,,,,,,1.147,,71.59,PAO,-1.784,0.100394,0.00222864,0.999441 kka2_1:8_D5D,kka2_1:8_5,Kka2,kka2_1:8,P00552,0.999441,NO,5,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.306,-1.306,,,,,,,,1.147,,71.59,PAO,-1.784,0.100394,0.00222864,0.999441 kka2_1:4_R122R,kka2_1:4_122,Kka2,kka2_1:4,P00552,0.999444,NO,122,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.175,-2.175,,,0.487,H,A,0.16,0.26,16.436,16.436,71.59,BBH,-1.53833,0.168804,0.00736512,0.999444 kka2_1:2_D156D,kka2_1:2_156,Kka2,kka2_1:2,P00552,0.999446,NO,156,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.696,-1.696,,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.295029,0.00926998,0.999446 kka2_1:2_L81L,kka2_1:2_81,Kka2,kka2_1:2,P00552,0.999446,NO,81,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.427,-1.427,,,0.46,E,A,1.59,-0.14,1.895,,63.64,HHA,-1.50567,0.295029,0.00805839,0.999446 PSD95pdz3_G364T,PSD95pdz3_364,PSD95pdz3,PSD95pdz3,P31016,0.999453,NO,364,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.008,-3.328,2.32,5.53299,,,,,21.28,,,,POH,-1.33667,0.0758425,0.00050942,0.999453 beta-lactamase_39_L248F,beta-lactamase_39_248,TEM-1,beta-lactamase_39,P62593,0.999454,NO,248,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.0495842,0.00428493,0.999454 beta-lactamase_156_G249H,beta-lactamase_156_249,TEM-1,beta-lactamase_156,P62593,0.999456,NO,249,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.111618,0.00220169,0.999456 kka2_1:8_A166A,kka2_1:8_166,Kka2,kka2_1:8,P00552,0.999457,NO,166,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.407,-2.407,,,0.534,,B,1.04,1.03,13.995,13.995,71.59,HHO,-2.421,0.100394,0.00799912,0.999457 kka2_1:8_A166A,kka2_1:8_166,Kka2,kka2_1:8,P00552,0.999457,NO,166,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.407,-2.407,,,0.534,,B,1.04,1.03,13.995,13.995,71.59,HHO,-2.421,0.100394,0.00799912,0.999457 kka2_1:8_G43G,kka2_1:8_43,Kka2,kka2_1:8,P00552,0.999457,NO,43,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.587,-1.587,,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.100394,0.0071925,0.999457 kka2_1:8_G43G,kka2_1:8_43,Kka2,kka2_1:8,P00552,0.999457,NO,43,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.587,-1.587,,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.100394,0.0071925,0.999457 kka2_1:8_I246I,kka2_1:8_246,Kka2,kka2_1:8,P00552,0.999457,NO,246,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-2.008,-2.008,,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.100394,0.0139479,0.999457 kka2_1:8_I246I,kka2_1:8_246,Kka2,kka2_1:8,P00552,0.999457,NO,246,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-2.008,-2.008,,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.100394,0.0139479,0.999457 kka2_1:8_I254I,kka2_1:8_254,Kka2,kka2_1:8,P00552,0.999457,NO,254,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.933,-1.933,,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.100394,0.0132375,0.999457 kka2_1:8_I254I,kka2_1:8_254,Kka2,kka2_1:8,P00552,0.999457,NO,254,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.933,-1.933,,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.100394,0.0132375,0.999457 beta-lactamase_625_Y44I,beta-lactamase_625_44,TEM-1,beta-lactamase_625,P62593,0.99946,NO,44,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-2.547,-2.364,-0.183,,,E,B,0.21,-0.45,2.371,,73.78,OHH,-1.86267,0.213352,0.00426364,0.99946 beta-lactamase_625_R189I,beta-lactamase_625_189,TEM-1,beta-lactamase_625,P62593,0.999465,NO,189,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.844,-4.147,2.303,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.213352,0.0050699,0.999465 kka2_1:4_E96N,kka2_1:4_96,Kka2,kka2_1:4,P00552,0.99947,NO,96,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.573,-3.878,1.305,,0.476,,B,1.52,-0.65,1.254,,71.59,OAH,-2.143,0.168804,0.00369441,0.99947 kka2_1:8_A56A,kka2_1:8_56,Kka2,kka2_1:8,P00552,0.999474,NO,56,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.083,-2.083,,,0.796,T,A,0.46,1.39,10.511,,71.59,OHH,-1.86867,0.100394,0.00717715,0.999474 kka2_1:8_A56A,kka2_1:8_56,Kka2,kka2_1:8,P00552,0.999474,NO,56,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.083,-2.083,,,0.796,T,A,0.46,1.39,10.511,,71.59,OHH,-1.86867,0.100394,0.00717715,0.999474 kka2_1:8_E17E,kka2_1:8_17,Kka2,kka2_1:8,P00552,0.999474,NO,17,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.154,-2.154,,,0.957,T,A,1.04,0.22,31.483,31.483,63.64,HAB,-2.432,0.100394,0.00688738,0.999474 kka2_1:8_E17E,kka2_1:8_17,Kka2,kka2_1:8,P00552,0.999474,NO,17,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.154,-2.154,,,0.957,T,A,1.04,0.22,31.483,31.483,63.64,HAB,-2.432,0.100394,0.00688738,0.999474 beta-lactamase_156_Q267H,beta-lactamase_156_267,TEM-1,beta-lactamase_156,P62593,0.999475,NO,267,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.111618,0.0102128,0.999475 Pab1_K164G,Pab1_164,Pab1,Pab1,P04147,0.999478,NO,164,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-2.298,-3.296,0.998,,,,,,,,,,OBP,-1.41767,0.175299,0.00255241,0.999478 beta-lactamase_156_G85I,beta-lactamase_156_85,TEM-1,beta-lactamase_156,P62593,0.999479,NO,85,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.011,-4.226,3.215,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.111618,0.00252173,0.999479 beta-lactamase_D36Y,beta-lactamase_36,TEM-1,beta-lactamase,P62593,0.999479,NO,36,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.732,-3.266,0.534,5.39764,0.555,H,A,0.11,1.17,13.689,13.689,77.62,AAP,-1.91167,0.221079,0.00476483,0.999479 beta-lactamase_H24R,beta-lactamase_24,TEM-1,beta-lactamase,P62593,0.999479,NO,24,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-2.481,-3.749,1.268,5.82767,,,,,,2.708,,93.01,HBO,-1.85167,0.221079,0.00238894,0.999479 beta-lactamase_156_R91T,beta-lactamase_156_91,TEM-1,beta-lactamase_156,P62593,0.999481,NO,91,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.392,-2.721,1.329,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.111618,0.00380226,0.999481 beta-lactamase_0_P105L,beta-lactamase_0_105,TEM-1,beta-lactamase_0,P62593,0.999483,NO,105,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.813,-3.581,2.768,,0.226,T,A,0.52,0.8,3.48,,63.29,POH,-1.01533,0.0500837,0.0011981,0.999483 beta-lactamase_39_L248C,beta-lactamase_39_248,TEM-1,beta-lactamase_39,P62593,0.999486,NO,248,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.0495842,0.00428493,0.999486 kka2_1:8_A13A,kka2_1:8_13,Kka2,kka2_1:8,P00552,0.99949,NO,13,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.248,-2.248,,,0.689,G,A,1.04,0.99,14.966,14.966,92.05,OHH,-1.646,0.100394,0.00784241,0.99949 kka2_1:8_A13A,kka2_1:8_13,Kka2,kka2_1:8,P00552,0.99949,NO,13,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.248,-2.248,,,0.689,G,A,1.04,0.99,14.966,14.966,92.05,OHH,-1.646,0.100394,0.00784241,0.99949 kka2_1:8_A14A,kka2_1:8_14,Kka2,kka2_1:8,P00552,0.99949,NO,14,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.837,-1.837,,,0.728,G,A,0.46,0.7,,,71.59,HHH,-1.82567,0.100394,0.00706614,0.99949 kka2_1:8_A14A,kka2_1:8_14,Kka2,kka2_1:8,P00552,0.99949,NO,14,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.837,-1.837,,,0.728,G,A,0.46,0.7,,,71.59,HHH,-1.82567,0.100394,0.00706614,0.99949 kka2_1:8_D82A,kka2_1:8_82,Kka2,kka2_1:8,P00552,0.99949,NO,82,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.946,-1.898,-0.048,,0.341,E,b,0.29,0.52,7.463,,63.64,HAH,-1.98,0.100394,0.00637516,0.99949 kka2_1:8_D82A,kka2_1:8_82,Kka2,kka2_1:8,P00552,0.99949,NO,82,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.946,-1.898,-0.048,,0.341,E,b,0.29,0.52,7.463,,63.64,HAH,-1.98,0.100394,0.00637516,0.99949 kka2_1:8_L7L,kka2_1:8_7,Kka2,kka2_1:8,P00552,0.99949,NO,7,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.926,-1.926,,,,,,,,,,71.59,OHB,-2.12333,0.100394,0.00269456,0.99949 kka2_1:8_L7L,kka2_1:8_7,Kka2,kka2_1:8,P00552,0.99949,NO,7,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.926,-1.926,,,,,,,,,,71.59,OHB,-2.12333,0.100394,0.00269456,0.99949 kka2_1:8_T130T,kka2_1:8_130,Kka2,kka2_1:8,P00552,0.99949,NO,130,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.392,-2.392,,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.100394,0.00804204,0.99949 kka2_1:8_T130T,kka2_1:8_130,Kka2,kka2_1:8,P00552,0.99949,NO,130,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.392,-2.392,,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.100394,0.00804204,0.99949 beta-lactamase_156_T116Q,beta-lactamase_156_116,TEM-1,beta-lactamase_156,P62593,0.999493,NO,116,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.28,-3.898,2.618,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.111618,0.00336175,0.999493 beta-lactamase_39_A246T,beta-lactamase_39_246,TEM-1,beta-lactamase_39,P62593,0.999493,NO,246,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.121,-3.507,1.386,,0.01,E,B,0.46,-1.01,1.331,,73.78,HHH,-1.55633,0.0495842,0.00569458,0.999493 kka2_1:2_V153V,kka2_1:2_153,Kka2,kka2_1:2,P00552,0.999493,NO,153,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.092,-1.092,,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.295029,0.00501119,0.999493 kka2_1:2_T85T,kka2_1:2_85,Kka2,kka2_1:2,P00552,0.999496,NO,85,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.165,-2.165,,,0.576,E,B,0.22,1.39,1.853,,71.59,HPA,-2.10133,0.295029,0.00634493,0.999496 Pab1_Y143R,Pab1_143,Pab1,Pab1,P04147,0.999496,NO,143,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-1.961,-3.619,1.658,,0.409,H,A,,0.3,,,,HHA,-1.39633,0.175299,0.00160364,0.999496 kka2_1:1_H162H,kka2_1:1_162,Kka2,kka2_1:1,P00552,0.999498,NO,162,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-2.319,-2.319,,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.520039,0.00616145,0.999498 kka2_1:1_H106H,kka2_1:1_106,Kka2,kka2_1:1,P00552,0.999501,NO,106,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-3.13,-3.13,,,1.065,.,a,0.17,-0.95,2.53,,71.59,PBH,-2.10433,0.520039,0.00730778,0.999501 kka2_1:2_A191A,kka2_1:2_191,Kka2,kka2_1:2,P00552,0.999502,NO,191,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.831,-0.831,,,,.,b,0.46,-0.94,2.046,,50,AHO,-0.868667,0.295029,0.00338807,0.999502 beta-lactamase_2500_T116E,beta-lactamase_2500_116,TEM-1,beta-lactamase_2500,P62593,0.999504,NO,116,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.28,-3.469,2.189,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.361275,0.00336175,0.999504 beta-lactamase_2500_T131S,beta-lactamase_2500_131,TEM-1,beta-lactamase_2500,P62593,0.999504,NO,131,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.328,-1.912,0.584,,,H,A,0.22,-0.69,3.048,,67.48,PPH,-1.00867,0.361275,0.00345886,0.999504 beta-lactamase_625_S256G,beta-lactamase_625_256,TEM-1,beta-lactamase_625,P62593,0.999505,NO,256,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.213352,0.00710634,0.999505 kka2_1:8_E111E,kka2_1:8_111,Kka2,kka2_1:8,P00552,0.999507,NO,111,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.28,-2.28,,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.100394,0.00746789,0.999507 kka2_1:8_E111E,kka2_1:8_111,Kka2,kka2_1:8,P00552,0.999507,NO,111,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.28,-2.28,,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.100394,0.00746789,0.999507 kka2_1:8_R147Q,kka2_1:8_147,Kka2,kka2_1:8,P00552,0.999507,NO,147,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.123,-2.836,1.713,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.100394,0.00549168,0.999507 kka2_1:8_R147Q,kka2_1:8_147,Kka2,kka2_1:8,P00552,0.999507,NO,147,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.123,-2.836,1.713,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.100394,0.00549168,0.999507 kka2_1:8_S114S,kka2_1:8_114,Kka2,kka2_1:8,P00552,0.999507,NO,114,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.527,-2.527,,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.100394,0.00705262,0.999507 kka2_1:8_S114S,kka2_1:8_114,Kka2,kka2_1:8,P00552,0.999507,NO,114,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.527,-2.527,,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.100394,0.00705262,0.999507 kka2_1:1_A79N,kka2_1:1_79,Kka2,kka2_1:1,P00552,0.999509,NO,79,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.368,-3.84,1.472,,0.563,.,B,0.46,-0.43,7.792,7.792,71.59,HHH,-1.752,0.520039,0.00664821,0.999509 beta-lactamase_39_K32W,beta-lactamase_39_32,TEM-1,beta-lactamase_39,P62593,0.999512,NO,32,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.984,-5.48,3.496,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.0495842,0.00401283,0.999512 kka2_1:2_E142E,kka2_1:2_142,Kka2,kka2_1:2,P00552,0.999512,NO,142,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.221,-2.221,,,0.471,H,A,1.52,0.85,3.693,,65.53,HAB,-2.08033,0.295029,0.00748883,0.999512 kka2_1:2_V75V,kka2_1:2_75,Kka2,kka2_1:2,P00552,0.999512,NO,75,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-2.06,-2.06,,,0.042,.,B,0.44,-0.2,2.815,,71.59,OHO,-1.563,0.295029,0.00693733,0.999512 beta-lactamase_625_H94S,beta-lactamase_625_94,TEM-1,beta-lactamase_625,P62593,0.999513,NO,94,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-2.5,-3.499,0.999,,0.776,,B,0.17,1.24,19.42,19.42,77.62,HBH,-1.872,0.213352,0.00389226,0.999513 kka2_1:4_T225T,kka2_1:4_225,Kka2,kka2_1:4,P00552,0.999513,NO,225,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.393,-2.393,,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.168804,0.0113598,0.999513 beta-lactamase_0_F64G,beta-lactamase_0_64,TEM-1,beta-lactamase_0,P62593,0.999515,NO,64,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-0.841,-3.583,2.742,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.0500837,0.000947691,0.999515 beta-lactamase_39_L167H,beta-lactamase_39_167,TEM-1,beta-lactamase_39,P62593,0.999517,NO,167,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.138,-4.852,3.714,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.0495842,0.00303566,0.999517 gb1_G264A,gb1_264,gb1,gb1,P06654,0.999517,NO,264,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.833,-2.168,0.335,,,,,,,0.864,,44.87,POH,-1.61267,0.177985,0.0049716,0.999517 beta-lactamase_2500_Q276M,beta-lactamase_2500_276,TEM-1,beta-lactamase_2500,P62593,0.999518,NO,276,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.361275,0.0191712,0.999518 beta-lactamase_156_V157S,beta-lactamase_156_157,TEM-1,beta-lactamase_156,P62593,0.999519,NO,157,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.751,-2.878,1.127,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.111618,0.00506849,0.999519 beta-lactamase_2500_N173G,beta-lactamase_2500_173,TEM-1,beta-lactamase_2500,P62593,0.99952,NO,173,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-2.663,-1.002,-1.661,,1.044,T,l,0.61,1.25,1.88,,77.62,OPA,-1.46633,0.361275,0.0033769,0.99952 beta-lactamase_625_R239T,beta-lactamase_625_239,TEM-1,beta-lactamase_625,P62593,0.999521,NO,239,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.213352,0.00213852,0.999521 kka2_1:4_E142E,kka2_1:4_142,Kka2,kka2_1:4,P00552,0.999523,NO,142,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.221,-2.221,,,0.471,H,A,1.52,0.85,3.693,,65.53,HAB,-2.08033,0.168804,0.00748883,0.999523 kka2_1:4_G151G,kka2_1:4_151,Kka2,kka2_1:4,P00552,0.999523,NO,151,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.873,-0.873,,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.168804,0.00339918,0.999523 kka2_1:4_G55G,kka2_1:4_55,Kka2,kka2_1:4,P00552,0.999523,NO,55,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.625,-1.625,,,0.517,S,b,0.75,1.19,15.753,15.753,63.64,POH,-2.05967,0.168804,0.00667877,0.999523 beta-lactamase_39_L135Y,beta-lactamase_39_135,TEM-1,beta-lactamase_39,P62593,0.999525,NO,135,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.002,-3.991,2.989,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.0495842,0.00244423,0.999525 beta-lactamase_156_T264L,beta-lactamase_156_264,TEM-1,beta-lactamase_156,P62593,0.999526,NO,264,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.111618,0.0119399,0.999526 beta-lactamase_625_A268W,beta-lactamase_625_268,TEM-1,beta-lactamase_625,P62593,0.999526,NO,268,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.213352,0.0102525,0.999526 kka2_1:4_K138K,kka2_1:4_138,Kka2,kka2_1:4,P00552,0.999527,NO,138,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-2.5,-2.5,,,0.594,H,A,1.3,0.98,21.267,21.267,71.59,HBB,-2.48833,0.168804,0.00628542,0.999527 beta-lactamase_39_W163N,beta-lactamase_39_163,TEM-1,beta-lactamase_39,P62593,0.999528,NO,163,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-1.843,-2.852,1.009,,0.467,,B,0.47,-0.5,15.095,15.095,63.99,BHA,-1.269,0.0495842,0.00418955,0.999528 kka2_1:4_Q100Q,kka2_1:4_100,Kka2,kka2_1:4,P00552,0.999534,NO,100,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.77,-2.77,,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.168804,0.0066405,0.999534 beta-lactamase_2500_R273L,beta-lactamase_2500_273,TEM-1,beta-lactamase_2500,P62593,0.999535,NO,273,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.314,-3.556,1.242,,0.564,H,A,1.2,1.57,19.943,19.943,73.78,ABP,-1.841,0.361275,0.0077952,0.999535 kka2_1:4_R44R,kka2_1:4_44,Kka2,kka2_1:4,P00552,0.999538,NO,44,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.062,-2.062,,,0.487,S,B,1.2,-0.35,5.71,,71.59,OBO,-1.80767,0.168804,0.00745043,0.999538 beta-lactamase_625_A148E,beta-lactamase_625_148,TEM-1,beta-lactamase_625,P62593,0.999539,NO,148,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.757,-2.317,0.56,,0.379,H,A,0.46,-0.55,1.359,,72.73,PHH,-1.40167,0.213352,0.00547053,0.999539 beta-lactamase_39_A247L,beta-lactamase_39_247,TEM-1,beta-lactamase_39,P62593,0.99954,NO,247,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.48,-2.56,1.08,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.0495842,0.00611275,0.99954 kka2_1:8_A35A,kka2_1:8_35,Kka2,kka2_1:8,P00552,0.99954,NO,35,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.127,-2.127,,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.100394,0.00630016,0.99954 kka2_1:8_A35A,kka2_1:8_35,Kka2,kka2_1:8,P00552,0.99954,NO,35,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.127,-2.127,,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.100394,0.00630016,0.99954 kka2_1:8_A9A,kka2_1:8_9,Kka2,kka2_1:8,P00552,0.99954,NO,9,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.079,-2.079,,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.100394,0.00273264,0.99954 kka2_1:8_A9A,kka2_1:8_9,Kka2,kka2_1:8,P00552,0.99954,NO,9,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.079,-2.079,,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.100394,0.00273264,0.99954 kka2_1:8_Q4Q,kka2_1:8_4,Kka2,kka2_1:8,P00552,0.99954,NO,4,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.361,-2.361,,,,,,,,2.026,,71.59,APA,-1.95533,0.100394,0.00239179,0.99954 kka2_1:8_Q4Q,kka2_1:8_4,Kka2,kka2_1:8,P00552,0.99954,NO,4,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.361,-2.361,,,,,,,,2.026,,71.59,APA,-1.95533,0.100394,0.00239179,0.99954 kka2_1:2_E111E,kka2_1:2_111,Kka2,kka2_1:2,P00552,0.999543,NO,111,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.28,-2.28,,,0.155,H,A,1.52,-1.14,2.792,,65.53,HAB,-2.27833,0.295029,0.00746789,0.999543 beta-lactamase_625_T126H,beta-lactamase_625_126,TEM-1,beta-lactamase_625,P62593,0.999547,NO,126,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.122,-4.699,3.577,,0.05,H,A,0.22,-0.05,0.817,,44.41,HPH,-1.60467,0.213352,0.00244552,0.999547 beta-lactamase_D207T,beta-lactamase_207,TEM-1,beta-lactamase,P62593,0.999547,NO,207,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.064,-2.565,0.501,5.40404,0.409,H,A,0.23,0.12,1.975,,77.62,HAH,-1.77033,0.221079,0.00592942,0.999547 beta-lactamase_39_R202A,beta-lactamase_39_202,TEM-1,beta-lactamase_39,P62593,0.999548,NO,202,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.292,-2.462,1.17,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.0495842,0.00321899,0.999548 beta-lactamase_625_W163E,beta-lactamase_625_163,TEM-1,beta-lactamase_625,P62593,0.999548,NO,163,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-1.843,-3.693,1.85,,0.467,,B,0.47,-0.5,5.019,,63.99,BHA,-1.269,0.213352,0.00418955,0.999548 kka2_1:1_Q26Q,kka2_1:1_26,Kka2,kka2_1:1,P00552,0.99955,NO,26,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.18,-2.18,,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.520039,0.00708962,0.99955 beta-lactamase_39_A148D,beta-lactamase_39_148,TEM-1,beta-lactamase_39,P62593,0.999555,NO,148,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.757,-2.341,0.584,,0.379,H,A,0.46,-0.55,3.551,,72.73,PHH,-1.40167,0.0495842,0.00547053,0.999555 kka2_1:8_A110A,kka2_1:8_110,Kka2,kka2_1:8,P00552,0.999556,NO,110,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.064,-2.064,,,0.175,H,A,1.04,-1.19,11.413,11.413,71.59,OHA,-1.91867,0.100394,0.00759851,0.999556 kka2_1:8_A110A,kka2_1:8_110,Kka2,kka2_1:8,P00552,0.999556,NO,110,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.064,-2.064,,,0.175,H,A,1.04,-1.19,11.413,11.413,71.59,OHA,-1.91867,0.100394,0.00759851,0.999556 kka2_1:8_G10G,kka2_1:8_10,Kka2,kka2_1:8,P00552,0.999556,NO,10,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.921,-1.921,,,,,,,,1.862,,71.59,HOP,-2.10733,0.100394,0.00289233,0.999556 kka2_1:8_G10G,kka2_1:8_10,Kka2,kka2_1:8,P00552,0.999556,NO,10,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.921,-1.921,,,,,,,,1.862,,71.59,HOP,-2.10733,0.100394,0.00289233,0.999556 kka2_1:8_T72T,kka2_1:8_72,Kka2,kka2_1:8,P00552,0.999556,NO,72,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.38,-2.38,,,0.784,H,A,0.22,0.29,3.603,,65.53,HPP,-2.238,0.100394,0.00750756,0.999556 kka2_1:8_T72T,kka2_1:8_72,Kka2,kka2_1:8,P00552,0.999556,NO,72,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.38,-2.38,,,0.784,H,A,0.22,0.29,3.603,,65.53,HPP,-2.238,0.100394,0.00750756,0.999556 kka2_1:8_V46V,kka2_1:8_46,Kka2,kka2_1:8,P00552,0.999556,NO,46,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-2.62,-2.62,,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.100394,0.00631301,0.999556 kka2_1:8_V46V,kka2_1:8_46,Kka2,kka2_1:8,P00552,0.999556,NO,46,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-2.62,-2.62,,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.100394,0.00631301,0.999556 beta-lactamase_156_G52A,beta-lactamase_156_52,TEM-1,beta-lactamase_156,P62593,0.999558,NO,52,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.149,-2.316,1.167,,0.299,,l,0.29,-0.04,1.179,,64.69,POB,-1.66267,0.111618,0.00340138,0.999558 kka2_1:2_A71A,kka2_1:2_71,Kka2,kka2_1:2,P00552,0.999562,NO,71,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.824,-1.824,,,0.553,H,A,0.46,0.08,9.788,,64.39,HHP,-1.74033,0.295029,0.00727707,0.999562 beta-lactamase_0_E166G,beta-lactamase_0_166,TEM-1,beta-lactamase_0,P62593,0.999563,NO,166,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.756,-2.741,0.985,,0.508,G,A,1.04,1.05,17.227,17.227,73.08,OAH,-1.42233,0.0500837,0.00512989,0.999563 beta-lactamase_625_R176V,beta-lactamase_625_176,TEM-1,beta-lactamase_625,P62593,0.999563,NO,176,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-0.863,-3.754,2.891,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.213352,0.00105554,0.999563 kka2_1:4_D134D,kka2_1:4_134,Kka2,kka2_1:4,P00552,0.999563,NO,134,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.969,-0.969,,,0.421,B,B,0.75,0.31,0.733,,49.62,HAB,-1.057,0.168804,0.00270812,0.999563 kka2_1:2_I246I,kka2_1:2_246,Kka2,kka2_1:2,P00552,0.999569,NO,246,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-2.008,-2.008,,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.295029,0.0139479,0.999569 beta-lactamase_156_E102S,beta-lactamase_156_102,TEM-1,beta-lactamase_156,P62593,0.999571,NO,102,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.118,-2.129,0.011,,0.722,S,B,1.04,1.82,15.721,15.721,73.08,HAH,-1.581,0.111618,0.00486633,0.999571 kka2_1:2_E235E,kka2_1:2_235,Kka2,kka2_1:2,P00552,0.999572,NO,235,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.955,-1.955,,,0.631,H,A,1.04,0.12,26.048,26.048,65.53,OAH,-2.07267,0.295029,0.0102806,0.999572 kka2_1:8_R18R,kka2_1:8_18,Kka2,kka2_1:8,P00552,0.999573,NO,18,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.055,-2.055,,,0.474,T,A,1.2,0.54,19.629,19.629,71.59,ABH,-1.821,0.100394,0.00724065,0.999573 kka2_1:8_R18R,kka2_1:8_18,Kka2,kka2_1:8,P00552,0.999573,NO,18,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.055,-2.055,,,0.474,T,A,1.2,0.54,19.629,19.629,71.59,ABH,-1.821,0.100394,0.00724065,0.999573 beta-lactamase_156_W288I,beta-lactamase_156_288,TEM-1,beta-lactamase_156,P62593,0.999574,NO,288,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,,,,,,,,,,,,,BHO,,0.111618,,0.999574 beta-lactamase_156_K213W,beta-lactamase_156_213,TEM-1,beta-lactamase_156,P62593,0.999579,NO,213,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.81,-5.386,3.576,,0.67,,A,2.34,0.29,3.924,,67.83,ABH,-1.57767,0.111618,0.00610411,0.999579 beta-lactamase_156_P105I,beta-lactamase_156_105,TEM-1,beta-lactamase_156,P62593,0.999579,NO,105,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.813,-4.008,3.195,,0.226,T,A,0.52,0.8,1.154,,63.29,POH,-1.01533,0.111618,0.0011981,0.999579 beta-lactamase_Q86H,beta-lactamase_86,TEM-1,beta-lactamase,P62593,0.99958,NO,86,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.4,-4.718,2.318,5.39897,0.696,S,A,0.12,2.38,2.105,,77.62,OPA,-1.61067,0.221079,0.00450027,0.99958 PSD95pdz3_A370F,PSD95pdz3_370,PSD95pdz3,PSD95pdz3,P31016,0.99958,NO,370,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.307,-3.749,2.442,5.22304,,,,,17.284,,,,PHP,-1.57967,0.0758425,0.000429106,0.99958 beta-lactamase_156_I54Q,beta-lactamase_156_54,TEM-1,beta-lactamase_156,P62593,0.999582,NO,54,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-2.838,-2.926,0.088,,0.669,E,B,0.48,-0.14,0.541,,73.78,BHH,-2.337,0.111618,0.00403589,0.999582 kka2_1:2_G21G,kka2_1:2_21,Kka2,kka2_1:2,P00552,0.999584,NO,21,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.368,-1.368,,,0.586,T,l,0.29,-0.75,2.026,,71.59,HOH,-2.10167,0.295029,0.00709648,0.999584 beta-lactamase_156_S96G,beta-lactamase_156_96,TEM-1,beta-lactamase_156,P62593,0.999585,NO,96,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.27,-2.481,0.211,,0.368,,b,0.27,0.39,2.838,,73.78,HPP,-2.019,0.111618,0.00551835,0.999585 beta-lactamase_39_Q97K,beta-lactamase_39_97,TEM-1,beta-lactamase_39,P62593,0.999585,NO,97,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.072,-2.314,0.242,,0.823,G,A,0.64,2.42,4.457,,77.62,PPP,-2.43833,0.0495842,0.0045116,0.999585 kka2_1:2_I254I,kka2_1:2_254,Kka2,kka2_1:2,P00552,0.999587,NO,254,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.933,-1.933,,,0.135,H,A,1.52,-0.6,2.562,,71.59,BHH,-1.668,0.295029,0.0132375,0.999587 kka2_1:2_P45P,kka2_1:2_45,Kka2,kka2_1:2,P00552,0.999588,NO,45,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.774,-1.774,,,0.669,,B,0.52,-0.76,4.882,,71.59,BOH,-2.152,0.295029,0.00590481,0.999588 kka2_1:8_A129A,kka2_1:8_129,Kka2,kka2_1:8,P00552,0.999589,NO,129,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.656,-1.656,,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.100394,0.00726862,0.999589 kka2_1:8_A129A,kka2_1:8_129,Kka2,kka2_1:8,P00552,0.999589,NO,129,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.656,-1.656,,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.100394,0.00726862,0.999589 kka2_1:8_A41A,kka2_1:8_41,Kka2,kka2_1:8,P00552,0.999589,NO,41,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.879,-1.879,,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.100394,0.00543332,0.999589 kka2_1:8_A41A,kka2_1:8_41,Kka2,kka2_1:8,P00552,0.999589,NO,41,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.879,-1.879,,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.100394,0.00543332,0.999589 kka2_1:2_A137I,kka2_1:2_137,Kka2,kka2_1:2,P00552,0.999597,NO,137,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.156,-2.375,0.219,,0.029,H,A,0.46,0.34,1.323,,63.26,PHB,-2.559,0.295029,0.00515054,0.999597 kka2_1:2_A191F,kka2_1:2_191,Kka2,kka2_1:2,P00552,0.999597,NO,191,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.831,-4.183,3.352,,,.,b,0.46,-0.94,2.046,,50,AHO,-0.868667,0.295029,0.00338807,0.999597 kka2_1:2_A41C,kka2_1:2_41,Kka2,kka2_1:2,P00552,0.999597,NO,41,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.879,-3.65,1.771,,0.184,.,B,0.46,-0.96,24.451,24.451,64.39,PHP,-2.477,0.295029,0.00543332,0.999597 kka2_1:2_C192T,kka2_1:2_192,Kka2,kka2_1:2,P00552,0.999597,NO,192,C,T,CT,Special,Polar,5.07,5.6,0.53,149,121,119,-2,108.5,116.1,7.6,-1.067,-2.666,1.599,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.295029,0.00485428,0.999597 kka2_1:2_C31K,kka2_1:2_31,Kka2,kka2_1:2,P00552,0.999597,NO,31,C,K,CK,Special,PositiveCharge,5.07,9.74,4.67,202,121,146,25,108.5,168.6,60.1,-2.246,-3.377,1.131,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.295029,0.00681582,0.999597 kka2_1:2_D154D,kka2_1:2_154,Kka2,kka2_1:2,P00552,0.999597,NO,154,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.876,-0.876,,,0.457,,b,0.29,1.48,3.631,,52.65,HAP,-1.52467,0.295029,0.00292633,0.999597 kka2_1:2_D238K,kka2_1:2_238,Kka2,kka2_1:2,P00552,0.999597,NO,238,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.83,-2.641,-0.189,,0.604,H,A,0.75,-0.33,22.789,22.789,92.05,HAB,-2.633,0.295029,0.0113863,0.999597 kka2_1:2_D33T,kka2_1:2_33,Kka2,kka2_1:2,P00552,0.999597,NO,33,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.186,-2.647,0.461,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.295029,0.00633568,0.999597 kka2_1:2_D52A,kka2_1:2_52,Kka2,kka2_1:2,P00552,0.999597,NO,52,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.271,-3.15,0.879,,0.22,E,B,0.75,0.8,1.123,,71.59,PAH,-2.38367,0.295029,0.00175694,0.999597 kka2_1:2_D5L,kka2_1:2_5,Kka2,kka2_1:2,P00552,0.999597,NO,5,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.306,-3.538,2.232,,,,,,,,,71.59,PAO,-1.784,0.295029,0.00222864,0.999597 kka2_1:2_D5N,kka2_1:2_5,Kka2,kka2_1:2,P00552,0.999597,NO,5,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.306,-3.103,1.797,,,,,,,,,71.59,PAO,-1.784,0.295029,0.00222864,0.999597 kka2_1:2_E231Y,kka2_1:2_231,Kka2,kka2_1:2,P00552,0.999597,NO,231,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.002,-4.332,2.33,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.295029,0.00732383,0.999597 kka2_1:2_E3Y,kka2_1:2_3,Kka2,kka2_1:2,P00552,0.999597,NO,3,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.199,-2.458,0.259,,,,,,,7.22,,92.05,HAP,-2.11567,0.295029,0.00267607,0.999597 kka2_1:2_F256W,kka2_1:2_256,Kka2,kka2_1:2,P00552,0.999597,NO,256,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.49,-2.846,1.356,,,H,A,0.58,-0.78,1.653,,53.03,HHH,-1.423,0.295029,0.0132841,0.999597 kka2_1:2_G234P,kka2_1:2_234,Kka2,kka2_1:2,P00552,0.999597,NO,234,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-2.9,-2.731,-0.169,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.295029,0.00984449,0.999597 kka2_1:2_G234Q,kka2_1:2_234,Kka2,kka2_1:2,P00552,0.999597,NO,234,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-2.9,-2.619,-0.281,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.295029,0.00984449,0.999597 kka2_1:2_G6E,kka2_1:2_6,Kka2,kka2_1:2,P00552,0.999597,NO,6,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.685,-3.379,1.694,,,,,,,,,71.59,AOH,-1.639,0.295029,0.00204693,0.999597 kka2_1:2_G6K,kka2_1:2_6,Kka2,kka2_1:2,P00552,0.999597,NO,6,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.685,-2.23,0.545,,,,,,,,,71.59,AOH,-1.639,0.295029,0.00204693,0.999597 kka2_1:2_G6M,kka2_1:2_6,Kka2,kka2_1:2,P00552,0.999597,NO,6,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.685,-4.549,2.864,,,,,,,,,71.59,AOH,-1.639,0.295029,0.00204693,0.999597 kka2_1:2_G6N,kka2_1:2_6,Kka2,kka2_1:2,P00552,0.999597,NO,6,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.685,-3.547,1.862,,,,,,,,,71.59,AOH,-1.639,0.295029,0.00204693,0.999597 kka2_1:2_G6P,kka2_1:2_6,Kka2,kka2_1:2,P00552,0.999597,NO,6,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.685,-2.187,0.502,,,,,,,,,71.59,AOH,-1.639,0.295029,0.00204693,0.999597 kka2_1:2_G6S,kka2_1:2_6,Kka2,kka2_1:2,P00552,0.999597,NO,6,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.685,-3.143,1.458,,,,,,,,,71.59,AOH,-1.639,0.295029,0.00204693,0.999597 kka2_1:2_G6T,kka2_1:2_6,Kka2,kka2_1:2,P00552,0.999597,NO,6,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.685,-3.379,1.694,,,,,,,,,71.59,AOH,-1.639,0.295029,0.00204693,0.999597 kka2_1:2_G6W,kka2_1:2_6,Kka2,kka2_1:2,P00552,0.999597,NO,6,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.685,-5.12,3.435,,,,,,,,,71.59,AOH,-1.639,0.295029,0.00204693,0.999597 kka2_1:2_G6Y,kka2_1:2_6,Kka2,kka2_1:2,P00552,0.999597,NO,6,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.685,-4.17,2.485,,,,,,,,,71.59,AOH,-1.639,0.295029,0.00204693,0.999597 kka2_1:2_H8E,kka2_1:2_8,Kka2,kka2_1:2,P00552,0.999597,NO,8,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-2.759,-3.378,0.619,,,,,,,,,71.59,HBH,-2.25467,0.295029,0.00256422,0.999597 kka2_1:2_I2K,kka2_1:2_2,Kka2,kka2_1:2,P00552,0.999597,NO,2,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.787,-3.536,1.749,,,,,,,5.773,,71.59,HHA,-1.92433,0.295029,0.00246644,0.999597 kka2_1:2_L158F,kka2_1:2_158,Kka2,kka2_1:2,P00552,0.999597,NO,158,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.947,-1.154,-0.793,,0.095,,B,1.59,0.77,7.588,,63.64,AHA,-1.25333,0.295029,0.00529068,0.999597 kka2_1:2_L158Y,kka2_1:2_158,Kka2,kka2_1:2,P00552,0.999597,NO,158,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.947,-3.398,1.451,,0.095,,B,1.59,0.77,7.588,,63.64,AHA,-1.25333,0.295029,0.00529068,0.999597 kka2_1:2_L165Y,kka2_1:2_165,Kka2,kka2_1:2,P00552,0.999597,NO,165,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-2.453,-4.292,1.839,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.295029,0.00801161,0.999597 kka2_1:2_L243E,kka2_1:2_243,Kka2,kka2_1:2,P00552,0.999597,NO,243,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-2.651,-2.717,0.066,,0.277,H,A,1.59,-0.67,13.165,13.165,92.05,HHH,-2.03767,0.295029,0.00884927,0.999597 kka2_1:2_L7C,kka2_1:2_7,Kka2,kka2_1:2,P00552,0.999597,NO,7,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.926,-4.785,2.859,,,,,,,3.012,,71.59,OHB,-2.12333,0.295029,0.00269456,0.999597 kka2_1:2_Q155V,kka2_1:2_155,Kka2,kka2_1:2,P00552,0.999597,NO,155,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.606,-2.82,0.214,,0.525,T,A,0.64,1.49,1.592,,63.64,APA,-1.726,0.295029,0.00641853,0.999597 kka2_1:2_Q155W,kka2_1:2_155,Kka2,kka2_1:2,P00552,0.999597,NO,155,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.606,-5.444,2.838,,0.525,T,A,0.64,1.49,1.592,,63.64,APA,-1.726,0.295029,0.00641853,0.999597 kka2_1:2_Q163I,kka2_1:2_163,Kka2,kka2_1:2,P00552,0.999597,NO,163,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.162,-3.594,1.432,,0.58,T,B,0.64,1.85,3.888,,64.02,BPO,-1.78333,0.295029,0.00719507,0.999597 kka2_1:2_Q163M,kka2_1:2_163,Kka2,kka2_1:2,P00552,0.999597,NO,163,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.162,-2.88,0.718,,0.58,T,B,0.64,1.85,3.888,,64.02,BPO,-1.78333,0.295029,0.00719507,0.999597 kka2_1:2_Q163V,kka2_1:2_163,Kka2,kka2_1:2,P00552,0.999597,NO,163,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.162,-2.687,0.525,,0.58,T,B,0.64,1.85,3.888,,64.02,BPO,-1.78333,0.295029,0.00719507,0.999597 kka2_1:2_R173M,kka2_1:2_173,Kka2,kka2_1:2,P00552,0.999597,NO,173,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.407,-4.764,2.357,,0.308,H,A,0.16,-0.13,15.389,15.389,65.53,HBH,-1.70533,0.295029,0.00784999,0.999597 kka2_1:2_R177C,kka2_1:2_177,Kka2,kka2_1:2,P00552,0.999597,NO,177,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.282,-5.144,2.862,,0.521,T,A,1.2,0.16,1.842,,63.64,HBH,-2.36967,0.295029,0.00768224,0.999597 kka2_1:2_R177E,kka2_1:2_177,Kka2,kka2_1:2,P00552,0.999597,NO,177,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.282,-2.717,0.435,,0.521,T,A,1.2,0.16,1.842,,63.64,HBH,-2.36967,0.295029,0.00768224,0.999597 kka2_1:2_R177F,kka2_1:2_177,Kka2,kka2_1:2,P00552,0.999597,NO,177,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.282,-4.359,2.077,,0.521,T,A,1.2,0.16,1.842,,63.64,HBH,-2.36967,0.295029,0.00768224,0.999597 kka2_1:2_R177G,kka2_1:2_177,Kka2,kka2_1:2,P00552,0.999597,NO,177,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.282,-2.48,0.198,,0.521,T,A,1.2,0.16,1.842,,63.64,HBH,-2.36967,0.295029,0.00768224,0.999597 kka2_1:2_R177I,kka2_1:2_177,Kka2,kka2_1:2,P00552,0.999597,NO,177,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.282,-3.929,1.647,,0.521,T,A,1.2,0.16,1.842,,63.64,HBH,-2.36967,0.295029,0.00768224,0.999597 kka2_1:2_R177L,kka2_1:2_177,Kka2,kka2_1:2,P00552,0.999597,NO,177,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.282,-2.255,-0.027,,0.521,T,A,1.2,0.16,1.842,,63.64,HBH,-2.36967,0.295029,0.00768224,0.999597 kka2_1:2_R177N,kka2_1:2_177,Kka2,kka2_1:2,P00552,0.999597,NO,177,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.282,-2.629,0.347,,0.521,T,A,1.2,0.16,1.842,,63.64,HBH,-2.36967,0.295029,0.00768224,0.999597 kka2_1:2_R177S,kka2_1:2_177,Kka2,kka2_1:2,P00552,0.999597,NO,177,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.282,-2.536,0.254,,0.521,T,A,1.2,0.16,1.842,,63.64,HBH,-2.36967,0.295029,0.00768224,0.999597 kka2_1:2_R177T,kka2_1:2_177,Kka2,kka2_1:2,P00552,0.999597,NO,177,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.282,-2.275,-0.007,,0.521,T,A,1.2,0.16,1.842,,63.64,HBH,-2.36967,0.295029,0.00768224,0.999597 kka2_1:2_R177W,kka2_1:2_177,Kka2,kka2_1:2,P00552,0.999597,NO,177,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.282,-5.514,3.232,,0.521,T,A,1.2,0.16,1.842,,63.64,HBH,-2.36967,0.295029,0.00768224,0.999597 kka2_1:2_R177Y,kka2_1:2_177,Kka2,kka2_1:2,P00552,0.999597,NO,177,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.282,-4.382,2.1,,0.521,T,A,1.2,0.16,1.842,,63.64,HBH,-2.36967,0.295029,0.00768224,0.999597 kka2_1:2_S11C,kka2_1:2_11,Kka2,kka2_1:2,P00552,0.999597,NO,11,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.322,-4.711,2.389,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.295029,0.00381691,0.999597 kka2_1:2_S11L,kka2_1:2_11,Kka2,kka2_1:2,P00552,0.999597,NO,11,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.322,-1.799,-0.523,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.295029,0.00381691,0.999597 kka2_1:2_S11M,kka2_1:2_11,Kka2,kka2_1:2,P00552,0.999597,NO,11,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.322,-2.896,0.574,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.295029,0.00381691,0.999597 kka2_1:2_S11Q,kka2_1:2_11,Kka2,kka2_1:2,P00552,0.999597,NO,11,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.322,-3.989,1.667,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.295029,0.00381691,0.999597 kka2_1:2_S11Y,kka2_1:2_11,Kka2,kka2_1:2,P00552,0.999597,NO,11,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.322,-4.097,1.775,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.295029,0.00381691,0.999597 kka2_1:2_S251W,kka2_1:2_251,Kka2,kka2_1:2,P00552,0.999597,NO,251,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.636,-5.587,2.951,,0.712,H,A,0.27,-0.25,32.832,32.832,71.59,APP,-2.09367,0.295029,0.0138916,0.999597 kka2_1:2_V242E,kka2_1:2_242,Kka2,kka2_1:2,P00552,0.999597,NO,242,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-2.687,-2.323,-0.364,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.295029,0.0102575,0.999597 kka2_1:2_V242K,kka2_1:2_242,Kka2,kka2_1:2,P00552,0.999597,NO,242,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-2.687,-2.489,-0.198,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.295029,0.0102575,0.999597 kka2_1:2_V242S,kka2_1:2_242,Kka2,kka2_1:2,P00552,0.999597,NO,242,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-2.687,-3.455,0.768,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.295029,0.0102575,0.999597 kka2_1:2_V242W,kka2_1:2_242,Kka2,kka2_1:2,P00552,0.999597,NO,242,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-2.687,-5.598,2.911,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.295029,0.0102575,0.999597 kka2_1:2_V46T,kka2_1:2_46,Kka2,kka2_1:2,P00552,0.999597,NO,46,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-2.62,-2.441,-0.179,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.295029,0.00631301,0.999597 beta-lactamase_156_A278G,beta-lactamase_156_278,TEM-1,beta-lactamase_156,P62593,0.999599,NO,278,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.111618,0.0310297,0.999599 beta-lactamase_625_L196Q,beta-lactamase_625_196,TEM-1,beta-lactamase_625,P62593,0.999599,NO,196,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-2.478,-3.242,0.764,,0.518,S,A,0.55,1.35,12.152,12.152,77.62,AHH,-1.839,0.213352,0.00512144,0.999599 kka2_1:4_D157D,kka2_1:4_157,Kka2,kka2_1:4,P00552,0.999599,NO,157,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.993,-0.993,,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.168804,0.0042313,0.999599 kka2_1:4_R239R,kka2_1:4_239,Kka2,kka2_1:4,P00552,0.999599,NO,239,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.949,-2.949,,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.168804,0.00835326,0.999599 beta-lactamase_156_Q267I,beta-lactamase_156_267,TEM-1,beta-lactamase_156,P62593,0.9996,NO,267,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.111618,0.0102128,0.9996 kka2_1:1_I141I,kka2_1:1_141,Kka2,kka2_1:1,P00552,0.999601,NO,141,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.495,-1.495,,,0.068,H,A,0.48,-0.01,7.546,7.546,92.05,BHA,-1.689,0.520039,0.00744745,0.999601 kka2_1:1_S68S,kka2_1:1_68,Kka2,kka2_1:1,P00552,0.999601,NO,68,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.623,-2.623,,,0.48,H,A,0.27,-0.1,2.655,,71.59,HPH,-1.40767,0.520039,0.00608265,0.999601 kka2_1:8_A255A,kka2_1:8_255,Kka2,kka2_1:8,P00552,0.999605,NO,255,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.715,-1.715,,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.100394,0.0126809,0.999605 kka2_1:8_A255A,kka2_1:8_255,Kka2,kka2_1:8,P00552,0.999605,NO,255,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.715,-1.715,,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.100394,0.0126809,0.999605 kka2_1:8_A25A,kka2_1:8_25,Kka2,kka2_1:8,P00552,0.999605,NO,25,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.496,-2.496,,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.100394,0.00595636,0.999605 kka2_1:8_A25A,kka2_1:8_25,Kka2,kka2_1:8,P00552,0.999605,NO,25,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.496,-2.496,,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.100394,0.00595636,0.999605 kka2_1:8_G181G,kka2_1:8_181,Kka2,kka2_1:8,P00552,0.999605,NO,181,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-2.698,-2.698,,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.100394,0.00728319,0.999605 kka2_1:8_G181G,kka2_1:8_181,Kka2,kka2_1:8,P00552,0.999605,NO,181,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-2.698,-2.698,,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.100394,0.00728319,0.999605 kka2_1:8_P76P,kka2_1:8_76,Kka2,kka2_1:8,P00552,0.999605,NO,76,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.449,-1.449,,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.100394,0.00625685,0.999605 kka2_1:8_P76P,kka2_1:8_76,Kka2,kka2_1:8,P00552,0.999605,NO,76,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.449,-1.449,,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.100394,0.00625685,0.999605 kka2_1:2_K138K,kka2_1:2_138,Kka2,kka2_1:2,P00552,0.999606,NO,138,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-2.5,-2.5,,,0.594,H,A,2.34,0.98,21.038,21.038,71.59,HBB,-2.48833,0.295029,0.00628542,0.999606 beta-lactamase_156_A282S,beta-lactamase_156_282,TEM-1,beta-lactamase_156,P62593,0.999609,NO,282,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.111618,0.0449821,0.999609 kka2_1:4_L81L,kka2_1:4_81,Kka2,kka2_1:4,P00552,0.999609,NO,81,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.427,-1.427,,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.168804,0.00805839,0.999609 beta-lactamase_I244V,beta-lactamase_244,TEM-1,beta-lactamase,P62593,0.999612,NO,244,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.555,-1.239,-0.316,5.35885,,E,B,0.01,-0.84,0.379,,77.62,HHH,-1.385,0.221079,0.00605379,0.999612 kka2_1:4_E169E,kka2_1:4_169,Kka2,kka2_1:4,P00552,0.999613,NO,169,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.996,-1.996,,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.168804,0.00730086,0.999613 beta-lactamase_156_G216Q,beta-lactamase_156_216,TEM-1,beta-lactamase_156,P62593,0.999616,NO,216,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.477,-3.862,2.385,,0.437,I,A,0.29,-0.58,12.464,12.464,74.48,HOO,-1.68067,0.111618,0.00639568,0.999616 kka2_1:1_I2T,kka2_1:1_2,Kka2,kka2_1:1,P00552,0.999618,NO,2,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.787,-2.02,0.233,,,,,,,2.329,,71.59,HHA,-1.92433,0.520039,0.00246644,0.999618 kka2_1:1_Q61Q,kka2_1:1_61,Kka2,kka2_1:1,P00552,0.999618,NO,61,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.982,-2.982,,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.520039,0.00612092,0.999618 beta-lactamase_156_P224E,beta-lactamase_156_224,TEM-1,beta-lactamase_156,P62593,0.999621,NO,224,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.893,-3.439,2.546,,0.383,,B,0.52,-0.3,0.383,,74.48,HOH,-1.26433,0.111618,0.00189564,0.999621 kka2_1:8_M178M,kka2_1:8_178,Kka2,kka2_1:8,P00552,0.999622,NO,178,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-3.206,-3.206,,,0.554,,b,1.59,0.68,13.268,13.268,71.59,BHO,-2.154,0.100394,0.00717253,0.999622 kka2_1:8_M178M,kka2_1:8_178,Kka2,kka2_1:8,P00552,0.999622,NO,178,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-3.206,-3.206,,,0.554,,b,1.59,0.68,13.268,13.268,71.59,BHO,-2.154,0.100394,0.00717253,0.999622 kka2_1:8_Q26Q,kka2_1:8_26,Kka2,kka2_1:8,P00552,0.999622,NO,26,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.18,-2.18,,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.100394,0.00708962,0.999622 kka2_1:8_Q26Q,kka2_1:8_26,Kka2,kka2_1:8,P00552,0.999622,NO,26,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.18,-2.18,,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.100394,0.00708962,0.999622 kka2_1:8_R143R,kka2_1:8_143,Kka2,kka2_1:8,P00552,0.999622,NO,143,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.525,-2.525,,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.100394,0.00662247,0.999622 kka2_1:8_R143R,kka2_1:8_143,Kka2,kka2_1:8,P00552,0.999622,NO,143,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.525,-2.525,,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.100394,0.00662247,0.999622 beta-lactamase_156_G52Y,beta-lactamase_156_52,TEM-1,beta-lactamase_156,P62593,0.999623,NO,52,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.149,-4.436,3.287,,0.299,,l,0.29,-0.04,1.179,,64.69,POB,-1.66267,0.111618,0.00340138,0.999623 beta-lactamase_156_S51W,beta-lactamase_156_51,TEM-1,beta-lactamase_156,P62593,0.999624,NO,51,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.526,-5.435,3.909,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.111618,0.00504821,0.999624 beta-lactamase_39_D99P,beta-lactamase_39_99,TEM-1,beta-lactamase_39,P62593,0.999624,NO,99,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.191,-3.8,2.609,,0.402,G,A,0.75,0.36,0.374,,64.69,PAH,-1.794,0.0495842,0.00305446,0.999624 kka2_1:1_E199E,kka2_1:1_199,Kka2,kka2_1:1,P00552,0.999624,NO,199,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.234,-2.234,,,0.508,E,B,1.04,-0.43,3.012,,65.53,HAP,-2.133,0.520039,0.00854122,0.999624 kka2_1:1_E3C,kka2_1:1_3,Kka2,kka2_1:1,P00552,0.999625,NO,3,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.199,-4.909,2.71,,,,,,,3.435,,92.05,HAP,-2.11567,0.520039,0.00267607,0.999625 beta-lactamase_156_R189E,beta-lactamase_156_189,TEM-1,beta-lactamase_156,P62593,0.999627,NO,189,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.844,-2.256,0.412,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.111618,0.0050699,0.999627 kka2_1:4_T85T,kka2_1:4_85,Kka2,kka2_1:4,P00552,0.999627,NO,85,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.165,-2.165,,,0.576,E,B,0.22,1.39,1.853,,71.59,HPA,-2.10133,0.168804,0.00634493,0.999627 beta-lactamase_156_S57H,beta-lactamase_156_57,TEM-1,beta-lactamase_156,P62593,0.99963,NO,57,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.918,-3.329,1.411,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.111618,0.00492804,0.99963 beta-lactamase_39_L73V,beta-lactamase_39_73,TEM-1,beta-lactamase_39,P62593,0.999631,NO,73,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.507,-2.286,0.779,,,H,A,0.55,-0.64,2.09,,67.83,HHH,-1.487,0.0495842,0.00488983,0.999631 beta-lactamase_625_S57T,beta-lactamase_625_57,TEM-1,beta-lactamase_625,P62593,0.999631,NO,57,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.918,-2.297,0.379,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.213352,0.00492804,0.999631 beta-lactamase_39_H24W,beta-lactamase_39_24,TEM-1,beta-lactamase_39,P62593,0.999648,NO,24,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-2.481,-5.305,2.824,,,,,,,2.708,,93.01,OBO,-2.0035,0.0495842,0.00238894,0.999648 kka2_1:4_R202R,kka2_1:4_202,Kka2,kka2_1:4,P00552,0.999649,NO,202,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.761,-1.761,,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.168804,0.00696498,0.999649 beta-lactamase_625_E56T,beta-lactamase_625_56,TEM-1,beta-lactamase_625,P62593,0.99965,NO,56,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.043,-2.013,-0.03,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.213352,0.00238534,0.99965 kka2_1:2_E86E,kka2_1:2_86,Kka2,kka2_1:2,P00552,0.999651,NO,86,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.86,-1.86,,,0.369,.,B,1.04,1.92,3.573,,63.26,PAH,-1.98067,0.295029,0.00642858,0.999651 beta-lactamase_156_H156L,beta-lactamase_156_156,TEM-1,beta-lactamase_156,P62593,0.999652,NO,156,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-3.156,-3.026,-0.13,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.111618,0.00468596,0.999652 beta-lactamase_156_G226D,beta-lactamase_156_226,TEM-1,beta-lactamase_156,P62593,0.999653,NO,226,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.461,-1.914,0.453,,0.701,T,l,0.29,-0.25,3.199,,74.48,HOH,-1.42933,0.111618,0.00665294,0.999653 PSD95pdz3_S371I,PSD95pdz3_371,PSD95pdz3,PSD95pdz3,P31016,0.999653,NO,371,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.86,-3.421,1.561,5.19744,,,,,17.1117,3.854,,87.71,HPB,-1.598,0.0758425,0.000847873,0.999653 beta-lactamase_625_E175H,beta-lactamase_625_175,TEM-1,beta-lactamase_625,P62593,0.999654,NO,175,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.336,-3.355,1.019,,0.551,,A,1.04,1.05,8.527,8.527,77.62,AAB,-1.31233,0.213352,0.00482205,0.999654 beta-lactamase_156_G85K,beta-lactamase_156_85,TEM-1,beta-lactamase_156,P62593,0.999655,NO,85,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.011,-2.219,1.208,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.111618,0.00252173,0.999655 kka2_1:8_A65A,kka2_1:8_65,Kka2,kka2_1:8,P00552,0.999655,NO,65,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.744,-1.744,,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.100394,0.00709258,0.999655 kka2_1:8_A65A,kka2_1:8_65,Kka2,kka2_1:8,P00552,0.999655,NO,65,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.744,-1.744,,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.100394,0.00709258,0.999655 kka2_1:8_E169E,kka2_1:8_169,Kka2,kka2_1:8,P00552,0.999655,NO,169,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.996,-1.996,,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.100394,0.00730086,0.999655 kka2_1:8_E169E,kka2_1:8_169,Kka2,kka2_1:8,P00552,0.999655,NO,169,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.996,-1.996,,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.100394,0.00730086,0.999655 kka2_1:8_K175K,kka2_1:8_175,Kka2,kka2_1:8,P00552,0.999655,NO,175,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-2.897,-2.897,,,0.579,H,A,2.34,0.51,15.316,15.316,71.59,HBH,-1.82333,0.100394,0.00693093,0.999655 kka2_1:8_K175K,kka2_1:8_175,Kka2,kka2_1:8,P00552,0.999655,NO,175,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-2.897,-2.897,,,0.579,H,A,2.34,0.51,15.316,15.316,71.59,HBH,-1.82333,0.100394,0.00693093,0.999655 beta-lactamase_625_Y262L,beta-lactamase_625_262,TEM-1,beta-lactamase_625,P62593,0.999657,NO,262,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.213352,0.00853516,0.999657 beta-lactamase_156_L73A,beta-lactamase_156_73,TEM-1,beta-lactamase_156,P62593,0.999661,NO,73,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.507,-2.475,0.968,,,H,A,0.55,-0.64,2.09,,67.83,HHH,-1.487,0.111618,0.00488983,0.999661 kka2_1:2_T225T,kka2_1:2_225,Kka2,kka2_1:2,P00552,0.999663,NO,225,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.393,-2.393,,,0.036,H,A,0.22,-1.22,4.554,,63.64,HPB,-1.58733,0.295029,0.0113598,0.999663 kka2_1:4_E161E,kka2_1:4_161,Kka2,kka2_1:4,P00552,0.999663,NO,161,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.581,-1.581,,,0.829,G,A,1.52,2.24,1.612,,92.05,AAB,-1.861,0.168804,0.00760103,0.999663 kka2_1:4_L103L,kka2_1:4_103,Kka2,kka2_1:4,P00552,0.999663,NO,103,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-2.362,-2.362,,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.168804,0.00574792,0.999663 kka2_1:1_N58N,kka2_1:1_58,Kka2,kka2_1:1,P00552,0.999667,NO,58,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-2.641,-2.641,,,0.131,S,A,0.61,0.72,30.755,30.755,71.59,HPA,-1.83033,0.520039,0.00793425,0.999667 beta-lactamase_625_R159S,beta-lactamase_625_159,TEM-1,beta-lactamase_625,P62593,0.999671,NO,159,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-0.94,-3.411,2.471,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.213352,0.00108472,0.999671 kka2_1:8_L165L,kka2_1:8_165,Kka2,kka2_1:8,P00552,0.999671,NO,165,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-2.453,-2.453,,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.100394,0.00801161,0.999671 kka2_1:8_L165L,kka2_1:8_165,Kka2,kka2_1:8,P00552,0.999671,NO,165,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-2.453,-2.453,,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.100394,0.00801161,0.999671 kka2_1:1_L60L,kka2_1:1_60,Kka2,kka2_1:1,P00552,0.999672,NO,60,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.997,-0.997,,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.520039,0.00262176,0.999672 beta-lactamase_625_H94Y,beta-lactamase_625_94,TEM-1,beta-lactamase_625,P62593,0.999674,NO,94,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-2.5,-4.209,1.709,,0.776,,B,0.17,1.24,19.42,19.42,77.62,HBH,-1.872,0.213352,0.00389226,0.999674 beta-lactamase_625_H151M,beta-lactamase_625_151,TEM-1,beta-lactamase_625,P62593,0.999676,NO,151,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-2.96,-4.581,1.621,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.213352,0.00216946,0.999676 beta-lactamase_156_K286C,beta-lactamase_156_286,TEM-1,beta-lactamase_156,P62593,0.999678,NO,286,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.111618,,0.999678 gb1_V247S,gb1_247,gb1,gb1,P06654,0.999678,NO,247,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.711,-3.168,1.457,,,,,,,0.805,,44.87,HHA,-1.485,0.177985,0.00435373,0.999678 beta-lactamase_625_S57A,beta-lactamase_625_57,TEM-1,beta-lactamase_625,P62593,0.99968,NO,57,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.918,-1.894,-0.024,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.213352,0.00492804,0.99968 beta-lactamase_156_A34I,beta-lactamase_156_34,TEM-1,beta-lactamase_156,P62593,0.999683,NO,34,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.059,-2.06,0.001,,,H,A,0.46,-0.54,3.614,,73.78,AHA,-1.74967,0.111618,0.00407913,0.999683 beta-lactamase_39_L205C,beta-lactamase_39_205,TEM-1,beta-lactamase_39,P62593,0.999683,NO,205,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.922,-4.692,3.77,,,H,A,0.55,-0.46,0.846,,42.31,PHH,-1.57767,0.0495842,0.00255802,0.999683 beta-lactamase_156_A282V,beta-lactamase_156_282,TEM-1,beta-lactamase_156,P62593,0.999685,NO,282,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.111618,0.0449821,0.999685 beta-lactamase_39_S122L,beta-lactamase_39_122,TEM-1,beta-lactamase_39,P62593,0.999687,NO,122,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.406,-2.918,0.512,,0.352,H,A,0.27,-0.54,2.004,,77.62,OPH,-1.39767,0.0495842,0.00497825,0.999687 kka2_1:1_Q27Q,kka2_1:1_27,Kka2,kka2_1:1,P00552,0.999687,NO,27,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-1.659,-1.659,,,0.608,.,A,0.64,0.71,0.521,,65.53,PPP,-1.90733,0.520039,0.00595365,0.999687 beta-lactamase_39_A123L,beta-lactamase_39_123,TEM-1,beta-lactamase_39,P62593,0.999688,NO,123,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.834,-3.096,2.262,,0.039,H,A,0.46,-0.72,0.705,,41.26,PHH,-1.47367,0.0495842,0.0010157,0.999688 kka2_1:2_A150A,kka2_1:2_150,Kka2,kka2_1:2,P00552,0.999688,NO,150,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.949,-0.949,,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.295029,0.0045009,0.999688 kka2_1:8_E230E,kka2_1:8_230,Kka2,kka2_1:8,P00552,0.999688,NO,230,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.672,-2.672,,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.100394,0.00920051,0.999688 kka2_1:8_E230E,kka2_1:8_230,Kka2,kka2_1:8,P00552,0.999688,NO,230,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.672,-2.672,,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.100394,0.00920051,0.999688 kka2_1:8_S68S,kka2_1:8_68,Kka2,kka2_1:8,P00552,0.999688,NO,68,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.623,-2.623,,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.100394,0.00608265,0.999688 kka2_1:8_S68S,kka2_1:8_68,Kka2,kka2_1:8,P00552,0.999688,NO,68,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.623,-2.623,,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.100394,0.00608265,0.999688 kka2_1:1_A247A,kka2_1:1_247,Kka2,kka2_1:1,P00552,0.999689,NO,247,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.459,-2.459,,,1.01,S,A,0.46,0.65,7.731,7.731,92.05,HHH,-2.197,0.520039,0.0102428,0.999689 Pab1_K180Q,Pab1_180,Pab1,Pab1,P04147,0.999691,NO,180,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.945,-2.469,0.524,,,,,,,,,,HBA,-1.575,0.175299,0.00295933,0.999691 beta-lactamase_156_F228E,beta-lactamase_156_228,TEM-1,beta-lactamase_156,P62593,0.999694,NO,228,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-2.342,-3.551,1.209,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.111618,0.0046669,0.999694 beta-lactamase_625_R118F,beta-lactamase_625_118,TEM-1,beta-lactamase_625,P62593,0.999694,NO,118,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.413,-4.338,1.925,,0.457,H,A,1.2,1.39,2.144,,77.62,HBA,-1.785,0.213352,0.00538794,0.999694 hsp90_S586T,hsp90_586,hsp90,hsp90,P02829,0.999695,NO,586,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.764,-2.8,0,4.65438,,,B,0.93,0.15,,,,HPH,-3.157,0.368192,0.000222939,0.999695 kka2_1:1_A14A,kka2_1:1_14,Kka2,kka2_1:1,P00552,0.999698,NO,14,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.837,-1.837,,,0.728,G,A,0.46,0.7,1.17,,71.59,HHH,-1.82567,0.520039,0.00706614,0.999698 beta-lactamase_625_A268G,beta-lactamase_625_268,TEM-1,beta-lactamase_625,P62593,0.999704,NO,268,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.213352,0.0102525,0.999704 kka2_1:8_A108A,kka2_1:8_108,Kka2,kka2_1:8,P00552,0.999704,NO,108,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.061,-2.061,,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.100394,0.00751209,0.999704 kka2_1:8_A108A,kka2_1:8_108,Kka2,kka2_1:8,P00552,0.999704,NO,108,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.061,-2.061,,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.100394,0.00751209,0.999704 kka2_1:8_G21G,kka2_1:8_21,Kka2,kka2_1:8,P00552,0.999704,NO,21,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.368,-1.368,,,0.586,T,l,0.29,-0.75,4.889,,71.59,HOH,-2.10167,0.100394,0.00709648,0.999704 kka2_1:8_G21G,kka2_1:8_21,Kka2,kka2_1:8,P00552,0.999704,NO,21,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.368,-1.368,,,0.586,T,l,0.29,-0.75,4.889,,71.59,HOH,-2.10167,0.100394,0.00709648,0.999704 kka2_1:8_P167P,kka2_1:8_167,Kka2,kka2_1:8,P00552,0.999704,NO,167,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-2.403,-2.403,,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.100394,0.00543203,0.999704 kka2_1:8_P167P,kka2_1:8_167,Kka2,kka2_1:8,P00552,0.999704,NO,167,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-2.403,-2.403,,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.100394,0.00543203,0.999704 kka2_1:8_V83V,kka2_1:8_83,Kka2,kka2_1:8,P00552,0.999704,NO,83,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-2.567,-2.567,,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.100394,0.00650486,0.999704 kka2_1:8_V83V,kka2_1:8_83,Kka2,kka2_1:8,P00552,0.999704,NO,83,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-2.567,-2.567,,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.100394,0.00650486,0.999704 beta-lactamase_156_G154P,beta-lactamase_156_154,TEM-1,beta-lactamase_156,P62593,0.999708,NO,154,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.823,-3.881,3.058,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.111618,0.00180205,0.999708 beta-lactamase_156_R59K,beta-lactamase_156_59,TEM-1,beta-lactamase_156,P62593,0.999709,NO,59,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.345,-2.351,1.006,,0.329,S,L,1.2,-0.09,2.995,,73.08,HBO,-2.24267,0.111618,0.00318082,0.999709 kka2_1:2_Q100Q,kka2_1:2_100,Kka2,kka2_1:2,P00552,0.99971,NO,100,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.77,-2.77,,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.295029,0.0066405,0.99971 kka2_1:1_D180D,kka2_1:1_180,Kka2,kka2_1:1,P00552,0.999712,NO,180,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.416,-2.416,,,1.03,S,a,0.75,1.5,1.534,,71.59,OAO,-2.02933,0.520039,0.00756412,0.999712 beta-lactamase_39_A183F,beta-lactamase_39_183,TEM-1,beta-lactamase_39,P62593,0.999714,NO,183,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.231,-4.164,2.933,,0.155,H,A,0.46,-0.91,1.237,,77.62,HHH,-1.53367,0.0495842,0.00296631,0.999714 kka2_1:1_E17E,kka2_1:1_17,Kka2,kka2_1:1,P00552,0.999715,NO,17,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.154,-2.154,,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.520039,0.00688738,0.999715 kka2_1:4_D250D,kka2_1:4_250,Kka2,kka2_1:4,P00552,0.999717,NO,250,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.015,-1.015,,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.168804,0.0177103,0.999717 kka2_1:4_E86E,kka2_1:4_86,Kka2,kka2_1:4,P00552,0.999717,NO,86,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.86,-1.86,,,0.369,.,B,1.04,1.92,4.451,,63.26,PAH,-1.98067,0.168804,0.00642858,0.999717 beta-lactamase_625_Y44F,beta-lactamase_625_44,TEM-1,beta-lactamase_625,P62593,0.999718,NO,44,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-2.547,-2.714,0.167,,,E,B,0.21,-0.45,2.371,,73.78,OHH,-1.86267,0.213352,0.00426364,0.999718 kka2_1:8_D33D,kka2_1:8_33,Kka2,kka2_1:8,P00552,0.999721,NO,33,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.186,-2.186,,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.100394,0.00633568,0.999721 kka2_1:8_D33D,kka2_1:8_33,Kka2,kka2_1:8,P00552,0.999721,NO,33,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.186,-2.186,,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.100394,0.00633568,0.999721 kka2_1:8_L243L,kka2_1:8_243,Kka2,kka2_1:8,P00552,0.999721,NO,243,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-2.651,-2.651,,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.100394,0.00884927,0.999721 kka2_1:8_L243L,kka2_1:8_243,Kka2,kka2_1:8,P00552,0.999721,NO,243,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-2.651,-2.651,,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.100394,0.00884927,0.999721 beta-lactamase_625_R189H,beta-lactamase_625_189,TEM-1,beta-lactamase_625,P62593,0.999724,NO,189,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.844,-2.544,0.7,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.213352,0.0050699,0.999724 kka2_1:1_E96E,kka2_1:1_96,Kka2,kka2_1:1,P00552,0.999727,NO,96,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.573,-2.573,,,0.476,,B,1.52,-0.65,1.254,,71.59,OAH,-2.143,0.520039,0.00369441,0.999727 kka2_1:4_P45P,kka2_1:4_45,Kka2,kka2_1:4,P00552,0.999728,NO,45,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.774,-1.774,,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.168804,0.00590481,0.999728 beta-lactamase_39_L167G,beta-lactamase_39_167,TEM-1,beta-lactamase_39,P62593,0.999736,NO,167,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.138,-3.694,2.556,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.0495842,0.00303566,0.999736 kka2_1:8_D250D,kka2_1:8_250,Kka2,kka2_1:8,P00552,0.999737,NO,250,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.015,-1.015,,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.100394,0.0177103,0.999737 kka2_1:8_D250D,kka2_1:8_250,Kka2,kka2_1:8,P00552,0.999737,NO,250,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.015,-1.015,,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.100394,0.0177103,0.999737 kka2_1:8_H106H,kka2_1:8_106,Kka2,kka2_1:8,P00552,0.999737,NO,106,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-3.13,-3.13,,,1.065,,a,0.87,-0.95,15.956,15.956,71.59,PBH,-2.10433,0.100394,0.00730778,0.999737 kka2_1:8_H106H,kka2_1:8_106,Kka2,kka2_1:8,P00552,0.999737,NO,106,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-3.13,-3.13,,,1.065,,a,0.87,-0.95,15.956,15.956,71.59,PBH,-2.10433,0.100394,0.00730778,0.999737 kka2_1:8_H8H,kka2_1:8_8,Kka2,kka2_1:8,P00552,0.999737,NO,8,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-2.759,-2.759,,,,,,,,,,71.59,HBH,-2.25467,0.100394,0.00256422,0.999737 kka2_1:8_H8H,kka2_1:8_8,Kka2,kka2_1:8,P00552,0.999737,NO,8,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-2.759,-2.759,,,,,,,,,,71.59,HBH,-2.25467,0.100394,0.00256422,0.999737 kka2_1:1_M178M,kka2_1:1_178,Kka2,kka2_1:1,P00552,0.999738,NO,178,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-3.206,-3.206,,,0.554,.,b,0.55,0.68,3.152,,71.59,BHO,-2.154,0.520039,0.00717253,0.999738 kka2_1:4_L158L,kka2_1:4_158,Kka2,kka2_1:4,P00552,0.999738,NO,158,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.947,-1.947,,,0.095,,B,1.59,0.77,7.588,,63.64,AHA,-1.25333,0.168804,0.00529068,0.999738 kka2_1:2_G151G,kka2_1:2_151,Kka2,kka2_1:2,P00552,0.999739,NO,151,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.873,-0.873,,,0.678,T,l,0.29,1.36,1.357,,49.62,HOH,-1.11433,0.295029,0.00339918,0.999739 beta-lactamase_39_E61F,beta-lactamase_39_61,TEM-1,beta-lactamase_39,P62593,0.99974,NO,61,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.115,-4.422,2.307,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.0495842,0.00440955,0.99974 beta-lactamase_2500_A84H,beta-lactamase_2500_84,TEM-1,beta-lactamase_2500,P62593,0.999741,NO,84,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.651,-3.344,1.693,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.361275,0.00503822,0.999741 beta-lactamase_156_L73P,beta-lactamase_156_73,TEM-1,beta-lactamase_156,P62593,0.999743,NO,73,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.507,-2.751,1.244,,,H,A,0.55,-0.64,2.09,,67.83,HHH,-1.487,0.111618,0.00488983,0.999743 beta-lactamase_2500_L196I,beta-lactamase_2500_196,TEM-1,beta-lactamase_2500,P62593,0.999743,NO,196,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-2.478,-2.648,0.17,,0.518,S,A,0.55,1.35,7.897,,77.62,AHH,-1.839,0.361275,0.00512144,0.999743 beta-lactamase_0_G243K,beta-lactamase_0_243,TEM-1,beta-lactamase_0,P62593,0.999744,NO,243,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.0500837,0.00464034,0.999744 kka2_1:1_A56A,kka2_1:1_56,Kka2,kka2_1:1,P00552,0.999744,NO,56,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.083,-2.083,,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.520039,0.00717715,0.999744 kka2_1:4_I29I,kka2_1:4_29,Kka2,kka2_1:4,P00552,0.999749,NO,29,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.692,-1.692,,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.168804,0.00619521,0.999749 Pab1_P135C,Pab1_135,Pab1,Pab1,P04147,0.999749,NO,135,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.457,-4.786,3.329,,,,,,,6.41,,81.8,BOA,-1.53367,0.175299,0.00148028,0.999749 beta-lactamase_156_N50D,beta-lactamase_156_50,TEM-1,beta-lactamase_156,P62593,0.999751,NO,50,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-2.979,-2.468,-0.511,,0.912,T,A,0.61,1.24,13.295,13.295,77.62,HPP,-2.134,0.111618,0.0047211,0.999751 beta-lactamase_156_L111Q,beta-lactamase_156_111,TEM-1,beta-lactamase_156,P62593,0.999753,NO,111,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.76,-3.108,1.348,,0.328,T,A,0.55,0.93,2.26,,64.34,BHP,-1.884,0.111618,0.00480671,0.999753 beta-lactamase_156_L89I,beta-lactamase_156_89,TEM-1,beta-lactamase_156,P62593,0.999753,NO,89,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.096,-3.166,2.07,,0.168,T,A,0.55,0.63,2.633,,64.34,PHO,-1.75767,0.111618,0.00207068,0.999753 kka2_1:8_A150A,kka2_1:8_150,Kka2,kka2_1:8,P00552,0.999753,NO,150,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.949,-0.949,,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.100394,0.0045009,0.999753 kka2_1:8_A150A,kka2_1:8_150,Kka2,kka2_1:8,P00552,0.999753,NO,150,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.949,-0.949,,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.100394,0.0045009,0.999753 kka2_1:8_K138K,kka2_1:8_138,Kka2,kka2_1:8,P00552,0.999753,NO,138,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-2.5,-2.5,,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.100394,0.00628542,0.999753 kka2_1:8_K138K,kka2_1:8_138,Kka2,kka2_1:8,P00552,0.999753,NO,138,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-2.5,-2.5,,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.100394,0.00628542,0.999753 kka2_1:8_R44R,kka2_1:8_44,Kka2,kka2_1:8,P00552,0.999753,NO,44,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.062,-2.062,,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.100394,0.00745043,0.999753 kka2_1:8_R44R,kka2_1:8_44,Kka2,kka2_1:8,P00552,0.999753,NO,44,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.062,-2.062,,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.100394,0.00745043,0.999753 kka2_1:2_V80V,kka2_1:2_80,Kka2,kka2_1:2,P00552,0.999754,NO,80,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.144,-1.144,,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.295029,0.00488211,0.999754 beta-lactamase_156_E46M,beta-lactamase_156_46,TEM-1,beta-lactamase_156,P62593,0.999755,NO,46,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.94,-4.375,2.435,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.111618,0.00427568,0.999755 beta-lactamase_156_P60A,beta-lactamase_156_60,TEM-1,beta-lactamase_156,P62593,0.999756,NO,60,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-2.469,-1.436,-1.033,,0.256,T,A,0.52,-0.56,2.947,,77.62,BOA,-1.97633,0.111618,0.00521318,0.999756 PSD95pdz3_A343K,PSD95pdz3_343,PSD95pdz3,PSD95pdz3,P31016,0.999757,NO,343,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.307,-3.139,1.832,5.585,,,,,14.728,,,,HHO,-1.22067,0.0758425,0.000798084,0.999757 kka2_1:4_R145R,kka2_1:4_145,Kka2,kka2_1:4,P00552,0.99976,NO,145,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.804,-1.804,,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.168804,0.00846663,0.99976 beta-lactamase_156_N173M,beta-lactamase_156_173,TEM-1,beta-lactamase_156,P62593,0.999761,NO,173,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-2.663,-4.901,2.238,,1.044,T,l,0.61,1.25,3.718,,77.62,OPA,-1.46633,0.111618,0.0033769,0.999761 kka2_1:1_P167P,kka2_1:1_167,Kka2,kka2_1:1,P00552,0.999764,NO,167,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-2.403,-2.403,,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.520039,0.00543203,0.999764 kka2_1:8_Q136Q,kka2_1:8_136,Kka2,kka2_1:8,P00552,0.99977,NO,136,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-3.021,-3.021,,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.100394,0.00624149,0.99977 kka2_1:8_Q136Q,kka2_1:8_136,Kka2,kka2_1:8,P00552,0.99977,NO,136,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-3.021,-3.021,,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.100394,0.00624149,0.99977 beta-lactamase_2500_S221H,beta-lactamase_2500_221,TEM-1,beta-lactamase_2500,P62593,0.999771,NO,221,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.754,-4.673,2.919,,0.624,H,A,0.27,-0.2,1.971,,74.48,BPH,-1.59967,0.361275,0.0046094,0.999771 beta-lactamase_625_A34V,beta-lactamase_625_34,TEM-1,beta-lactamase_625,P62593,0.999771,NO,34,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.059,-2.227,0.168,,,H,A,0.46,-0.54,3.614,,73.78,AHA,-1.74967,0.213352,0.00407913,0.999771 beta-lactamase_156_P255I,beta-lactamase_156_255,TEM-1,beta-lactamase_156,P62593,0.999772,NO,255,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.111618,0.00499612,0.999772 kka2_1:1_E63E,kka2_1:1_63,Kka2,kka2_1:1,P00552,0.999772,NO,63,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-0.762,-0.762,,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.520039,0.00118399,0.999772 beta-lactamase_156_M180V,beta-lactamase_156_180,TEM-1,beta-lactamase_156,P62593,0.999773,NO,180,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-2.795,-3.273,0.478,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.111618,0.00552048,0.999773 beta-lactamase_39_L55A,beta-lactamase_39_55,TEM-1,beta-lactamase_39,P62593,0.999774,NO,55,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.86,-2.512,0.652,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.0495842,0.00403741,0.999774 beta-lactamase_625_P250R,beta-lactamase_625_250,TEM-1,beta-lactamase_625,P62593,0.999775,NO,250,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.213352,0.00550899,0.999775 beta-lactamase_39_L191N,beta-lactamase_39_191,TEM-1,beta-lactamase_39,P62593,0.999778,NO,191,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.087,-4.164,3.077,,,H,A,0.55,0.09,1.372,,63.29,BHH,-1.445,0.0495842,0.00263549,0.999778 beta-lactamase_2500_N173S,beta-lactamase_2500_173,TEM-1,beta-lactamase_2500,P62593,0.999779,NO,173,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-2.663,-3.203,0.54,,1.044,T,l,0.61,1.25,1.88,,77.62,OPA,-1.46633,0.361275,0.0033769,0.999779 kka2_1:4_P76P,kka2_1:4_76,Kka2,kka2_1:4,P00552,0.999785,NO,76,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.449,-1.449,,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.168804,0.00625685,0.999785 kka2_1:8_A71A,kka2_1:8_71,Kka2,kka2_1:8,P00552,0.999786,NO,71,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.824,-1.824,,,0.553,H,A,0.46,0.08,18.64,18.64,64.39,HHP,-1.74033,0.100394,0.00727707,0.999786 kka2_1:8_A71A,kka2_1:8_71,Kka2,kka2_1:8,P00552,0.999786,NO,71,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.824,-1.824,,,0.553,H,A,0.46,0.08,18.64,18.64,64.39,HHP,-1.74033,0.100394,0.00727707,0.999786 kka2_1:8_L47L,kka2_1:8_47,Kka2,kka2_1:8,P00552,0.999786,NO,47,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.265,-1.265,,,0.139,E,B,1.59,-0.86,5.086,,63.26,HHH,-1.77933,0.100394,0.00509386,0.999786 kka2_1:8_L47L,kka2_1:8_47,Kka2,kka2_1:8,P00552,0.999786,NO,47,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.265,-1.265,,,0.139,E,B,1.59,-0.86,5.086,,63.26,HHH,-1.77933,0.100394,0.00509386,0.999786 kka2_1:8_L53L,kka2_1:8_53,Kka2,kka2_1:8,P00552,0.999786,NO,53,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-2.681,-2.681,,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.100394,0.00671168,0.999786 kka2_1:8_L53L,kka2_1:8_53,Kka2,kka2_1:8,P00552,0.999786,NO,53,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-2.681,-2.681,,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.100394,0.00671168,0.999786 kka2_1:8_S54S,kka2_1:8_54,Kka2,kka2_1:8,P00552,0.999786,NO,54,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.471,-2.471,,,0.408,S,b,0.77,1.01,13.679,13.679,71.59,HPO,-2.259,0.100394,0.00782867,0.999786 kka2_1:8_S54S,kka2_1:8_54,Kka2,kka2_1:8,P00552,0.999786,NO,54,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.471,-2.471,,,0.408,S,b,0.77,1.01,13.679,13.679,71.59,HPO,-2.259,0.100394,0.00782867,0.999786 kka2_1:8_T28T,kka2_1:8_28,Kka2,kka2_1:8,P00552,0.999786,NO,28,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.883,-1.883,,,0.353,S,B,0.22,2.02,18.114,18.114,63.64,PPH,-1.74467,0.100394,0.00743084,0.999786 kka2_1:8_T28T,kka2_1:8_28,Kka2,kka2_1:8,P00552,0.999786,NO,28,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.883,-1.883,,,0.353,S,B,0.22,2.02,18.114,18.114,63.64,PPH,-1.74467,0.100394,0.00743084,0.999786 kka2_1:8_V84V,kka2_1:8_84,Kka2,kka2_1:8,P00552,0.999786,NO,84,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-2.279,-2.279,,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.100394,0.00724019,0.999786 kka2_1:8_V84V,kka2_1:8_84,Kka2,kka2_1:8,P00552,0.999786,NO,84,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-2.279,-2.279,,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.100394,0.00724019,0.999786 kka2_1:2_I29I,kka2_1:2_29,Kka2,kka2_1:2,P00552,0.999789,NO,29,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.692,-1.692,,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.295029,0.00619521,0.999789 beta-lactamase_156_Q86I,beta-lactamase_156_86,TEM-1,beta-lactamase_156,P62593,0.999792,NO,86,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.4,-3.877,1.477,,0.696,S,A,0.64,2.38,27.704,27.704,77.62,OPA,-1.61067,0.111618,0.00450027,0.999792 kka2_1:4_L152L,kka2_1:4_152,Kka2,kka2_1:4,P00552,0.999792,NO,152,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.521,-1.521,,,0.547,,A,1.59,1.36,2.318,,63.64,OHH,-1.162,0.168804,0.00674868,0.999792 kka2_1:1_M120M,kka2_1:1_120,Kka2,kka2_1:1,P00552,0.999795,NO,120,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-3.877,-3.877,,,,H,A,0.55,-0.42,2.259,,92.05,HHB,-2.16733,0.520039,0.00265808,0.999795 kka2_1:2_R202R,kka2_1:2_202,Kka2,kka2_1:2,P00552,0.999795,NO,202,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.761,-1.761,,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.295029,0.00696498,0.999795 beta-lactamase_39_A185L,beta-lactamase_39_185,TEM-1,beta-lactamase_39,P62593,0.999796,NO,185,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.406,-2.064,0.658,,,H,A,0.46,-1.02,2.68,,65.03,HHP,-1.84033,0.0495842,0.00467449,0.999796 beta-lactamase_39_L146C,beta-lactamase_39_146,TEM-1,beta-lactamase_39,P62593,0.999798,NO,146,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.462,-4.847,3.385,,0.007,H,A,0.55,-0.56,1.953,,64.69,AHP,-1.656,0.0495842,0.00474542,0.999798 beta-lactamase_156_A77H,beta-lactamase_156_77,TEM-1,beta-lactamase_156,P62593,0.999801,NO,77,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.234,-3.165,1.931,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.111618,0.00282362,0.999801 kka2_1:1_R143R,kka2_1:1_143,Kka2,kka2_1:1,P00552,0.999803,NO,143,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.525,-2.525,,,0.325,H,A,0.16,1.22,3.6,,65.53,ABH,-1.86833,0.520039,0.00662247,0.999803 kka2_1:8_T225T,kka2_1:8_225,Kka2,kka2_1:8,P00552,0.999803,NO,225,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.393,-2.393,,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.100394,0.0113598,0.999803 kka2_1:8_T225T,kka2_1:8_225,Kka2,kka2_1:8,P00552,0.999803,NO,225,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.393,-2.393,,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.100394,0.0113598,0.999803 beta-lactamase_0_I277A,beta-lactamase_0_277,TEM-1,beta-lactamase_0,P62593,0.999804,NO,277,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.0500837,0.0169305,0.999804 beta-lactamase_625_E61R,beta-lactamase_625_61,TEM-1,beta-lactamase_625,P62593,0.999804,NO,61,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.115,-3.845,1.73,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.213352,0.00440955,0.999804 kka2_1:2_L57L,kka2_1:2_57,Kka2,kka2_1:2,P00552,0.999805,NO,57,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.898,-1.898,,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.295029,0.00723769,0.999805 kka2_1:2_N58N,kka2_1:2_58,Kka2,kka2_1:2,P00552,0.999805,NO,58,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-2.641,-2.641,,,0.131,S,A,0.43,0.72,5.729,,71.59,HPA,-1.83033,0.295029,0.00793425,0.999805 kka2_1:1_E59E,kka2_1:1_59,Kka2,kka2_1:1,P00552,0.999806,NO,59,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-0.952,-0.952,,,0.187,.,L,1.04,0.62,2.648,,50.38,PAH,-1.53,0.520039,0.00280355,0.999806 kka2_1:1_S40S,kka2_1:1_40,Kka2,kka2_1:1,P00552,0.999806,NO,40,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.645,-2.645,,,0.32,E,B,0.27,-0.9,25.997,25.997,71.59,HPH,-1.91567,0.520039,0.00693477,0.999806 beta-lactamase_39_T178E,beta-lactamase_39_178,TEM-1,beta-lactamase_39,P62593,0.999808,NO,178,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-0.791,-3.44,2.649,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.0495842,0.000684366,0.999808 beta-lactamase_625_N152F,beta-lactamase_625_152,TEM-1,beta-lactamase_625,P62593,0.999808,NO,152,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-2.757,-4.363,1.606,,0.863,H,A,0.61,0.92,2.061,,77.62,BPH,-2.97,0.213352,0.00471429,0.999808 beta-lactamase_39_P250S,beta-lactamase_39_250,TEM-1,beta-lactamase_39,P62593,0.999809,NO,250,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.0495842,0.00550899,0.999809 beta-lactamase_2500_P60H,beta-lactamase_2500_60,TEM-1,beta-lactamase_2500,P62593,0.999812,NO,60,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-2.469,-3.266,0.797,,0.256,T,A,0.52,-0.56,1.581,,77.62,BOA,-1.97633,0.361275,0.00521318,0.999812 beta-lactamase_625_V82W,beta-lactamase_625_82,TEM-1,beta-lactamase_625,P62593,0.999813,NO,82,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.325,-5.421,4.096,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.213352,0.00397046,0.999813 kka2_1:2_R239R,kka2_1:2_239,Kka2,kka2_1:2,P00552,0.999814,NO,239,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.949,-2.949,,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.295029,0.00835326,0.999814 kka2_1:1_L81L,kka2_1:1_81,Kka2,kka2_1:1,P00552,0.999815,NO,81,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.427,-1.427,,,0.46,E,A,0.55,-0.14,0.374,,63.64,HHA,-1.50567,0.520039,0.00805839,0.999815 beta-lactamase_625_A200D,beta-lactamase_625_200,TEM-1,beta-lactamase_625,P62593,0.999816,NO,200,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.878,-2.929,1.051,,0.757,H,A,0.46,-0.19,12.672,12.672,77.62,HHP,-2.001,0.213352,0.0060056,0.999816 kka2_1:1_S54S,kka2_1:1_54,Kka2,kka2_1:1,P00552,0.999818,NO,54,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.471,-2.471,,,0.408,S,b,0.27,1.01,6.085,,71.59,HPO,-2.259,0.520039,0.00782867,0.999818 kka2_1:8_E142E,kka2_1:8_142,Kka2,kka2_1:8,P00552,0.999819,NO,142,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.221,-2.221,,,0.471,H,A,1.04,0.85,2.655,,65.53,HAB,-2.08033,0.100394,0.00748883,0.999819 kka2_1:8_E142E,kka2_1:8_142,Kka2,kka2_1:8,P00552,0.999819,NO,142,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.221,-2.221,,,0.471,H,A,1.04,0.85,2.655,,65.53,HAB,-2.08033,0.100394,0.00748883,0.999819 kka2_1:8_E161E,kka2_1:8_161,Kka2,kka2_1:8,P00552,0.999819,NO,161,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.581,-1.581,,,0.829,G,A,1.04,2.24,11.923,11.923,92.05,AAB,-1.861,0.100394,0.00760103,0.999819 kka2_1:8_E161E,kka2_1:8_161,Kka2,kka2_1:8,P00552,0.999819,NO,161,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.581,-1.581,,,0.829,G,A,1.04,2.24,11.923,11.923,92.05,AAB,-1.861,0.100394,0.00760103,0.999819 kka2_1:8_E86E,kka2_1:8_86,Kka2,kka2_1:8,P00552,0.999819,NO,86,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.86,-1.86,,,0.369,,B,1.52,1.92,,,63.26,PAH,-1.98067,0.100394,0.00642858,0.999819 kka2_1:8_E86E,kka2_1:8_86,Kka2,kka2_1:8,P00552,0.999819,NO,86,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.86,-1.86,,,0.369,,B,1.52,1.92,,,63.26,PAH,-1.98067,0.100394,0.00642858,0.999819 kka2_1:8_Q61Q,kka2_1:8_61,Kka2,kka2_1:8,P00552,0.999819,NO,61,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.982,-2.982,,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.100394,0.00612092,0.999819 kka2_1:8_Q61Q,kka2_1:8_61,Kka2,kka2_1:8,P00552,0.999819,NO,61,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.982,-2.982,,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.100394,0.00612092,0.999819 kka2_1:8_T125T,kka2_1:8_125,Kka2,kka2_1:8,P00552,0.999819,NO,125,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.622,-2.622,,,0.791,T,A,0.22,0.33,2.675,,92.05,BPH,-1.56933,0.100394,0.00821755,0.999819 kka2_1:8_T125T,kka2_1:8_125,Kka2,kka2_1:8,P00552,0.999819,NO,125,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.622,-2.622,,,0.791,T,A,0.22,0.33,2.675,,92.05,BPH,-1.56933,0.100394,0.00821755,0.999819 beta-lactamase_39_M184Y,beta-lactamase_39_184,TEM-1,beta-lactamase_39,P62593,0.999822,NO,184,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.593,-4.027,2.434,,,H,A,0.55,-0.87,2.893,,62.94,HHH,-1.41,0.0495842,0.00356019,0.999822 kka2_1:2_T72T,kka2_1:2_72,Kka2,kka2_1:2,P00552,0.999824,NO,72,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.38,-2.38,,,0.784,H,A,0.82,0.29,6.463,,65.53,HPP,-2.238,0.295029,0.00750756,0.999824 beta-lactamase_625_M270A,beta-lactamase_625_270,TEM-1,beta-lactamase_625,P62593,0.999826,NO,270,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.213352,0.00767762,0.999826 kka2_1:1_T28T,kka2_1:1_28,Kka2,kka2_1:1,P00552,0.999826,NO,28,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.883,-1.883,,,0.353,S,B,0.22,2.02,1.12,,63.64,PPH,-1.74467,0.520039,0.00743084,0.999826 beta-lactamase_39_F58H,beta-lactamase_39_58,TEM-1,beta-lactamase_39,P62593,0.999827,NO,58,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-2.914,-2.092,-0.822,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.0495842,0.00523369,0.999827 kka2_1:1_A87A,kka2_1:1_87,Kka2,kka2_1:1,P00552,0.999832,NO,87,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.917,-1.917,,,1.039,S,L,0.46,1.57,20.738,20.738,65.53,AHO,-1.822,0.520039,0.00791281,0.999832 kka2_1:1_L57L,kka2_1:1_57,Kka2,kka2_1:1,P00552,0.999832,NO,57,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.898,-1.898,,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.520039,0.00723769,0.999832 kka2_1:2_D157D,kka2_1:2_157,Kka2,kka2_1:2,P00552,0.999833,NO,157,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.993,-0.993,,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.295029,0.0042313,0.999833 kka2_1:1_L243L,kka2_1:1_243,Kka2,kka2_1:1,P00552,0.999835,NO,243,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-2.651,-2.651,,,0.277,H,A,0.55,-0.67,4.334,,92.05,HHH,-2.03767,0.520039,0.00884927,0.999835 beta-lactamase_156_S96L,beta-lactamase_156_96,TEM-1,beta-lactamase_156,P62593,0.999836,NO,96,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.27,-3.527,1.257,,0.368,,b,0.27,0.39,2.838,,73.78,HPP,-2.019,0.111618,0.00551835,0.999836 kka2_1:2_I141I,kka2_1:2_141,Kka2,kka2_1:2,P00552,0.999836,NO,141,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.495,-1.495,,,0.068,H,A,0.48,-0.01,0.819,,92.05,BHA,-1.689,0.295029,0.00744745,0.999836 kka2_1:8_A87A,kka2_1:8_87,Kka2,kka2_1:8,P00552,0.999836,NO,87,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.917,-1.917,,,1.039,S,L,0.46,1.57,16.115,16.115,65.53,AHO,-1.822,0.100394,0.00791281,0.999836 kka2_1:8_A87A,kka2_1:8_87,Kka2,kka2_1:8,P00552,0.999836,NO,87,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.917,-1.917,,,1.039,S,L,0.46,1.57,16.115,16.115,65.53,AHO,-1.822,0.100394,0.00791281,0.999836 kka2_1:8_D52D,kka2_1:8_52,Kka2,kka2_1:8,P00552,0.999836,NO,52,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.271,-2.271,,,0.22,E,B,0.75,0.8,5.447,,71.59,PAH,-2.38367,0.100394,0.00175694,0.999836 kka2_1:8_D52D,kka2_1:8_52,Kka2,kka2_1:8,P00552,0.999836,NO,52,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.271,-2.271,,,0.22,E,B,0.75,0.8,5.447,,71.59,PAH,-2.38367,0.100394,0.00175694,0.999836 kka2_1:8_Q100Q,kka2_1:8_100,Kka2,kka2_1:8,P00552,0.999836,NO,100,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.77,-2.77,,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.100394,0.0066405,0.999836 kka2_1:8_Q100Q,kka2_1:8_100,Kka2,kka2_1:8,P00552,0.999836,NO,100,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.77,-2.77,,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.100394,0.0066405,0.999836 beta-lactamase_M67G,beta-lactamase_67,TEM-1,beta-lactamase,P62593,0.999838,NO,67,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-2.231,-2.754,0.523,4.9618,0.006,G,P,1.07,-0.81,1.463,,65.03,HHP,-1.502,0.221079,0.00409753,0.999838 beta-lactamase_T261V,beta-lactamase_261,TEM-1,beta-lactamase,P62593,0.999838,NO,261,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.88,-2.424,-0.456,5.65483,0.014,E,B,0.53,-0.39,2.449,,77.62,HPP,-1.771,0.221079,0.0123091,0.999838 kka2_1:4_A64A,kka2_1:4_64,Kka2,kka2_1:4,P00552,0.999839,NO,64,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.496,-1.496,,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.168804,0.00705578,0.999839 kka2_1:1_E86E,kka2_1:1_86,Kka2,kka2_1:1,P00552,0.999841,NO,86,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.86,-1.86,,,0.369,.,B,1.04,1.92,18.506,18.506,63.26,PAH,-1.98067,0.520039,0.00642858,0.999841 kka2_1:1_L70L,kka2_1:1_70,Kka2,kka2_1:1,P00552,0.999841,NO,70,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.017,-1.017,,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.520039,0.00411884,0.999841 beta-lactamase_156_A182W,beta-lactamase_156_182,TEM-1,beta-lactamase_156,P62593,0.999848,NO,182,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.777,-5.53,3.753,,0.136,H,A,0.46,-0.66,16.784,16.784,93.01,OHH,-1.27367,0.111618,0.00559099,0.999848 kka2_1:4_P179P,kka2_1:4_179,Kka2,kka2_1:4,P00552,0.99985,NO,179,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.974,-0.974,,,0.113,,B,0.52,0.69,10.913,10.913,56.06,HOA,-2.19867,0.168804,0.00298346,0.99985 beta-lactamase_2500_T193V,beta-lactamase_2500_193,TEM-1,beta-lactamase_2500,P62593,0.999852,NO,193,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.914,-2.673,0.759,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.361275,0.00482669,0.999852 kka2_1:8_D101A,kka2_1:8_101,Kka2,kka2_1:8,P00552,0.999852,NO,101,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.028,-2.654,1.626,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.100394,0.00423361,0.999852 kka2_1:8_D101A,kka2_1:8_101,Kka2,kka2_1:8,P00552,0.999852,NO,101,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.028,-2.654,1.626,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.100394,0.00423361,0.999852 kka2_1:8_D154D,kka2_1:8_154,Kka2,kka2_1:8,P00552,0.999852,NO,154,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.876,-0.876,,,0.457,,b,0.29,1.48,0.844,,52.65,HAP,-1.52467,0.100394,0.00292633,0.999852 kka2_1:8_D154D,kka2_1:8_154,Kka2,kka2_1:8,P00552,0.999852,NO,154,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.876,-0.876,,,0.457,,b,0.29,1.48,0.844,,52.65,HAP,-1.52467,0.100394,0.00292633,0.999852 beta-lactamase_2500_T138G,beta-lactamase_2500_138,TEM-1,beta-lactamase_2500,P62593,0.999853,NO,138,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.506,-2.767,0.261,,0.662,H,A,0.22,-0.03,30.445,30.445,73.78,HPP,-1.81233,0.361275,0.00487868,0.999853 beta-lactamase_156_L100A,beta-lactamase_156_100,TEM-1,beta-lactamase_156,P62593,0.999856,NO,100,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.218,-3.158,1.94,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.111618,0.00413885,0.999856 beta-lactamase_0_E46Q,beta-lactamase_0_46,TEM-1,beta-lactamase_0,P62593,0.999862,NO,46,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.94,-4.007,2.067,,0.021,E,B,1.04,0.14,30.306,30.306,59.44,HAH,-2.079,0.0500837,0.00427568,0.999862 kka2_1:2_L60L,kka2_1:2_60,Kka2,kka2_1:2,P00552,0.999862,NO,60,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.997,-0.997,,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.295029,0.00262176,0.999862 beta-lactamase_625_R92N,beta-lactamase_625_92,TEM-1,beta-lactamase_625,P62593,0.999863,NO,92,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.718,-2.988,1.27,,0.479,E,B,1.2,1.36,3.069,,65.38,BBH,-1.50367,0.213352,0.00429626,0.999863 beta-lactamase_0_N168E,beta-lactamase_0_168,TEM-1,beta-lactamase_0,P62593,0.999864,NO,168,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-1.029,-3.29,2.261,,0.113,G,A,0.61,-0.4,0.881,,44.41,HPA,-1.13233,0.0500837,0.00288667,0.999864 beta-lactamase_156_L167I,beta-lactamase_156_167,TEM-1,beta-lactamase_156,P62593,0.999866,NO,167,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.138,-3.085,1.947,,0.015,G,A,0.55,-0.63,0.4,,64.69,AHP,-1.30767,0.111618,0.00303566,0.999866 kka2_1:1_L93L,kka2_1:1_93,Kka2,kka2_1:1,P00552,0.999866,NO,93,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.815,-0.815,,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.520039,0.00131498,0.999866 kka2_1:1_Y22Y,kka2_1:1_22,Kka2,kka2_1:1,P00552,0.999866,NO,22,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-1.583,-1.583,,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.520039,0.00598977,0.999866 beta-lactamase_156_I125L,beta-lactamase_156_125,TEM-1,beta-lactamase_156,P62593,0.999867,NO,125,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.441,-1.939,0.498,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.111618,0.00383964,0.999867 beta-lactamase_156_L79A,beta-lactamase_156_79,TEM-1,beta-lactamase_156,P62593,0.999867,NO,79,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.842,-3.103,2.261,,0.007,H,A,0.55,-0.16,1.831,,50.35,HHP,-1.44333,0.111618,0.000947397,0.999867 beta-lactamase_39_K32G,beta-lactamase_39_32,TEM-1,beta-lactamase_39,P62593,0.999867,NO,32,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.984,-3.506,1.522,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.0495842,0.00401283,0.999867 kka2_1:4_G95G,kka2_1:4_95,Kka2,kka2_1:4,P00552,0.999867,NO,95,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-2.403,-2.403,,,0.126,E,B,0.29,-0.74,0.359,,71.59,HOA,-2.198,0.168804,0.00743616,0.999867 kka2_1:2_R44R,kka2_1:2_44,Kka2,kka2_1:2,P00552,0.999868,NO,44,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.062,-2.062,,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.295029,0.00745043,0.999868 kka2_1:8_D154E,kka2_1:8_154,Kka2,kka2_1:8,P00552,0.999869,NO,154,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.876,-2.369,1.493,,0.457,,b,0.29,1.48,0.844,,52.65,HAP,-1.52467,0.100394,0.00292633,0.999869 kka2_1:8_D154E,kka2_1:8_154,Kka2,kka2_1:8,P00552,0.999869,NO,154,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.876,-2.369,1.493,,0.457,,b,0.29,1.48,0.844,,52.65,HAP,-1.52467,0.100394,0.00292633,0.999869 kka2_1:8_D180D,kka2_1:8_180,Kka2,kka2_1:8,P00552,0.999869,NO,180,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.416,-2.416,,,1.03,S,a,0.75,1.5,14.668,14.668,71.59,OAO,-2.02933,0.100394,0.00756412,0.999869 kka2_1:8_D180D,kka2_1:8_180,Kka2,kka2_1:8,P00552,0.999869,NO,180,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.416,-2.416,,,1.03,S,a,0.75,1.5,14.668,14.668,71.59,OAO,-2.02933,0.100394,0.00756412,0.999869 kka2_1:8_L103L,kka2_1:8_103,Kka2,kka2_1:8,P00552,0.999869,NO,103,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-2.362,-2.362,,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.100394,0.00574792,0.999869 kka2_1:8_L103L,kka2_1:8_103,Kka2,kka2_1:8,P00552,0.999869,NO,103,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-2.362,-2.362,,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.100394,0.00574792,0.999869 beta-lactamase_156_Q204L,beta-lactamase_156_204,TEM-1,beta-lactamase_156,P62593,0.99987,NO,204,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-1.382,-2.716,1.334,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.111618,0.00364106,0.99987 Pab1_G193N,Pab1_193,Pab1,Pab1,P04147,0.999872,NO,193,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.414,-2.018,0.604,,,,,,,,,,POP,-1.55733,0.175299,0.0014922,0.999872 beta-lactamase_156_Q86V,beta-lactamase_156_86,TEM-1,beta-lactamase_156,P62593,0.999873,NO,86,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.4,-2.988,0.588,,0.696,S,A,0.64,2.38,27.704,27.704,77.62,OPA,-1.61067,0.111618,0.00450027,0.999873 kka2_1:4_A191A,kka2_1:4_191,Kka2,kka2_1:4,P00552,0.999878,NO,191,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.831,-0.831,,,,.,b,0.46,-0.94,2.046,,50,AHO,-0.868667,0.168804,0.00338807,0.999878 beta-lactamase_625_H110M,beta-lactamase_625_110,TEM-1,beta-lactamase_625,P62593,0.999879,NO,110,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-1.706,-3.324,1.618,,0.341,G,a,0.17,1.08,31.31,31.31,64.69,BBH,-1.73333,0.213352,0.00441499,0.999879 kka2_1:2_E161E,kka2_1:2_161,Kka2,kka2_1:2,P00552,0.99988,NO,161,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.581,-1.581,,,0.829,G,A,1.52,2.24,1.612,,92.05,AAB,-1.861,0.295029,0.00760103,0.99988 kka2_1:1_K175K,kka2_1:1_175,Kka2,kka2_1:1,P00552,0.999889,NO,175,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-2.897,-2.897,,,0.579,H,A,1.3,0.51,9.33,9.33,71.59,HBH,-1.82333,0.520039,0.00693093,0.999889 kka2_1:2_L152L,kka2_1:2_152,Kka2,kka2_1:2,P00552,0.99989,NO,152,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.521,-1.521,,,0.547,.,A,0.55,1.36,4.526,,63.64,OHH,-1.162,0.295029,0.00674868,0.99989 kka2_1:1_D90D,kka2_1:1_90,Kka2,kka2_1:1,P00552,0.999892,NO,90,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.459,-2.459,,,0.104,E,B,0.75,0.73,6.085,,64.39,BAH,-1.72833,0.520039,0.00583842,0.999892 kka2_1:1_L67L,kka2_1:1_67,Kka2,kka2_1:1,P00552,0.999892,NO,67,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.741,-0.741,,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.520039,0.00102787,0.999892 kka2_1:1_A34A,kka2_1:1_34,Kka2,kka2_1:1,P00552,0.9999,NO,34,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.928,-0.928,,,0.417,.,B,0.46,2.29,0.262,,52.27,AHH,-1.747,0.520039,0.00343484,0.9999 kka2_1:1_A9A,kka2_1:1_9,Kka2,kka2_1:1,P00552,0.9999,NO,9,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.079,-2.079,,,,,,,,0.383,,71.59,BHO,-2.253,0.520039,0.00273264,0.9999 kka2_1:1_L47L,kka2_1:1_47,Kka2,kka2_1:1,P00552,0.9999,NO,47,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.265,-1.265,,,0.139,E,B,0.55,-0.86,14.593,14.593,63.26,HHH,-1.77933,0.520039,0.00509386,0.9999 kka2_1:1_T85T,kka2_1:1_85,Kka2,kka2_1:1,P00552,0.9999,NO,85,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.165,-2.165,,,0.576,E,B,0.82,1.39,16.653,16.653,71.59,HPA,-2.10133,0.520039,0.00634493,0.9999 kka2_1:4_L57L,kka2_1:4_57,Kka2,kka2_1:4,P00552,0.9999,NO,57,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.898,-1.898,,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.168804,0.00723769,0.9999 kka2_1:4_M1M,kka2_1:4_1,Kka2,kka2_1:4,P00552,0.9999,NO,1,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.787,-1.787,,,,,,,,1.347,,62.12,NAHH,-1.787,0.168804,0.00251939,0.9999 kka2_1:8_A137A,kka2_1:8_137,Kka2,kka2_1:8,P00552,0.999901,NO,137,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.156,-2.156,,,0.029,H,A,1.04,0.34,2.886,,63.26,PHB,-2.559,0.100394,0.00515054,0.999901 kka2_1:8_A137A,kka2_1:8_137,Kka2,kka2_1:8,P00552,0.999901,NO,137,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.156,-2.156,,,0.029,H,A,1.04,0.34,2.886,,63.26,PHB,-2.559,0.100394,0.00515054,0.999901 kka2_1:8_R239R,kka2_1:8_239,Kka2,kka2_1:8,P00552,0.999901,NO,239,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.949,-2.949,,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.100394,0.00835326,0.999901 kka2_1:8_R239R,kka2_1:8_239,Kka2,kka2_1:8,P00552,0.999901,NO,239,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.949,-2.949,,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.100394,0.00835326,0.999901 beta-lactamase_625_A247I,beta-lactamase_625_247,TEM-1,beta-lactamase_625,P62593,0.999902,NO,247,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.213352,0.00611275,0.999902 kka2_1:2_E169E,kka2_1:2_169,Kka2,kka2_1:2,P00552,0.999902,NO,169,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.996,-1.996,,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.295029,0.00730086,0.999902 beta-lactamase_625_L111I,beta-lactamase_625_111,TEM-1,beta-lactamase_625,P62593,0.999904,NO,111,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.76,-2.153,0.393,,0.328,T,A,0.55,0.93,2.26,,64.34,BHP,-1.884,0.213352,0.00480671,0.999904 beta-lactamase_2500_A247M,beta-lactamase_2500_247,TEM-1,beta-lactamase_2500,P62593,0.999905,NO,247,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.361275,0.00611275,0.999905 beta-lactamase_2500_N50K,beta-lactamase_2500_50,TEM-1,beta-lactamase_2500,P62593,0.999905,NO,50,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-2.979,-3.578,0.599,,0.912,T,A,0.61,1.24,1.581,,77.62,HPP,-2.134,0.361275,0.0047211,0.999905 beta-lactamase_156_T193V,beta-lactamase_156_193,TEM-1,beta-lactamase_156,P62593,0.999906,NO,193,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.914,-2.673,0.759,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.111618,0.00482669,0.999906 beta-lactamase_2500_S283T,beta-lactamase_2500_283,TEM-1,beta-lactamase_2500,P62593,0.999911,NO,283,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.361275,0.0429138,0.999911 beta-lactamase_39_D177N,beta-lactamase_39_177,TEM-1,beta-lactamase_39,P62593,0.999912,NO,177,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.967,-2.571,1.604,,0.006,T,L,0.75,-1.02,3.536,,64.69,BAP,-0.873667,0.0495842,0.000864022,0.999912 beta-lactamase_625_A200S,beta-lactamase_625_200,TEM-1,beta-lactamase_625,P62593,0.999914,NO,200,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.878,-2.183,0.305,,0.757,H,A,0.46,-0.19,12.672,12.672,77.62,HHP,-2.001,0.213352,0.0060056,0.999914 kka2_1:4_A229A,kka2_1:4_229,Kka2,kka2_1:4,P00552,0.999914,NO,229,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.739,-1.739,,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.168804,0.00942138,0.999914 beta-lactamase_625_G141A,beta-lactamase_625_141,TEM-1,beta-lactamase_625,P62593,0.999916,NO,141,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.828,-2.988,2.16,,0.575,T,l,0.29,-0.28,0.198,,64.69,HOO,-1.08933,0.213352,0.0012419,0.999916 kka2_1:1_A191A,kka2_1:1_191,Kka2,kka2_1:1,P00552,0.999917,NO,191,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.831,-0.831,,,,.,b,0.46,-0.94,0.53,,50,AHO,-0.868667,0.520039,0.00338807,0.999917 kka2_1:1_I29I,kka2_1:1_29,Kka2,kka2_1:1,P00552,0.999917,NO,29,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.692,-1.692,,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.520039,0.00619521,0.999917 kka2_1:1_R18R,kka2_1:1_18,Kka2,kka2_1:1,P00552,0.999917,NO,18,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.055,-2.055,,,0.474,T,A,1.2,0.54,11.422,11.422,71.59,ABH,-1.821,0.520039,0.00724065,0.999917 beta-lactamase_156_N98F,beta-lactamase_156_98,TEM-1,beta-lactamase_156,P62593,0.999918,NO,98,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-2.973,-3.271,0.298,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.111618,0.00505389,0.999918 kka2_1:8_C31C,kka2_1:8_31,Kka2,kka2_1:8,P00552,0.999918,NO,31,C,C,CC,Special,Special,5.07,5.07,0,0,121,121,0,108.5,108.5,0,-2.246,-2.246,,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.100394,0.00681582,0.999918 kka2_1:8_C31C,kka2_1:8_31,Kka2,kka2_1:8,P00552,0.999918,NO,31,C,C,CC,Special,Special,5.07,5.07,0,0,121,121,0,108.5,108.5,0,-2.246,-2.246,,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.100394,0.00681582,0.999918 kka2_1:8_D118D,kka2_1:8_118,Kka2,kka2_1:8,P00552,0.999918,NO,118,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.07,-2.07,,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.100394,0.0067852,0.999918 kka2_1:8_D118D,kka2_1:8_118,Kka2,kka2_1:8,P00552,0.999918,NO,118,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.07,-2.07,,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.100394,0.0067852,0.999918 kka2_1:8_D134D,kka2_1:8_134,Kka2,kka2_1:8,P00552,0.999918,NO,134,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.969,-0.969,,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.100394,0.00270812,0.999918 kka2_1:8_D134D,kka2_1:8_134,Kka2,kka2_1:8,P00552,0.999918,NO,134,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.969,-0.969,,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.100394,0.00270812,0.999918 kka2_1:8_D156D,kka2_1:8_156,Kka2,kka2_1:8,P00552,0.999918,NO,156,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.696,-1.696,,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.100394,0.00926998,0.999918 kka2_1:8_D156D,kka2_1:8_156,Kka2,kka2_1:8,P00552,0.999918,NO,156,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.696,-1.696,,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.100394,0.00926998,0.999918 kka2_1:8_G151G,kka2_1:8_151,Kka2,kka2_1:8,P00552,0.999918,NO,151,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.873,-0.873,,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.100394,0.00339918,0.999918 kka2_1:8_G151G,kka2_1:8_151,Kka2,kka2_1:8,P00552,0.999918,NO,151,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.873,-0.873,,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.100394,0.00339918,0.999918 kka2_1:4_A78G,kka2_1:4_78,Kka2,kka2_1:4,P00552,0.999921,NO,78,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.744,-3.281,1.537,,0.078,.,B,0.46,-0.53,0.594,,56.06,OHH,-1.863,0.168804,0.00457299,0.999921 kka2_1:4_D118D,kka2_1:4_118,Kka2,kka2_1:4,P00552,0.999925,NO,118,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.07,-2.07,,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.168804,0.0067852,0.999925 beta-lactamase_39_D99C,beta-lactamase_39_99,TEM-1,beta-lactamase_39,P62593,0.999927,NO,99,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.191,-5.117,3.926,,0.402,G,A,0.75,0.36,0.374,,64.69,PAH,-1.794,0.0495842,0.00305446,0.999927 beta-lactamase_625_T112D,beta-lactamase_625_112,TEM-1,beta-lactamase_625,P62593,0.999929,NO,112,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.186,-2.66,0.474,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.213352,0.00531334,0.999929 beta-lactamase_39_M270V,beta-lactamase_39_270,TEM-1,beta-lactamase_39,P62593,0.999933,NO,270,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.0495842,0.00767762,0.999933 kka2_1:4_P249Q,kka2_1:4_249,Kka2,kka2_1:4,P00552,0.999934,NO,249,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.867,-4.234,2.367,,0.406,.,B,0.52,-0.01,,,92.05,HOA,-1.66867,0.168804,0.011045,0.999934 kka2_1:8_A71V,kka2_1:8_71,Kka2,kka2_1:8,P00552,0.999934,NO,71,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.824,-3.693,1.869,,0.553,H,A,0.46,0.08,18.64,18.64,64.39,HHP,-1.74033,0.100394,0.00727707,0.999934 kka2_1:8_A71V,kka2_1:8_71,Kka2,kka2_1:8,P00552,0.999934,NO,71,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.824,-3.693,1.869,,0.553,H,A,0.46,0.08,18.64,18.64,64.39,HHP,-1.74033,0.100394,0.00727707,0.999934 kka2_1:8_Q27Q,kka2_1:8_27,Kka2,kka2_1:8,P00552,0.999934,NO,27,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-1.659,-1.659,,,0.608,.,A,0.64,0.71,3.919,,65.53,PPP,-1.90733,0.100394,0.00595365,0.999934 kka2_1:8_Q27Q,kka2_1:8_27,Kka2,kka2_1:8,P00552,0.999934,NO,27,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-1.659,-1.659,,,0.608,.,A,0.64,0.71,3.919,,65.53,PPP,-1.90733,0.100394,0.00595365,0.999934 kka2_1:8_T85T,kka2_1:8_85,Kka2,kka2_1:8,P00552,0.999934,NO,85,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.165,-2.165,,,0.576,E,B,0.22,1.39,22.154,22.154,71.59,HPA,-2.10133,0.100394,0.00634493,0.999934 kka2_1:8_T85T,kka2_1:8_85,Kka2,kka2_1:8,P00552,0.999934,NO,85,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.165,-2.165,,,0.576,E,B,0.22,1.39,22.154,22.154,71.59,HPA,-2.10133,0.100394,0.00634493,0.999934 beta-lactamase_625_K32C,beta-lactamase_625_32,TEM-1,beta-lactamase_625,P62593,0.999937,NO,32,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.984,-5.093,3.109,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.213352,0.00401283,0.999937 beta-lactamase_39_S80A,beta-lactamase_39_80,TEM-1,beta-lactamase_39,P62593,0.999938,NO,80,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.029,-1.631,-0.398,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.0495842,0.00565569,0.999938 kka2_1:1_K50K,kka2_1:1_50,Kka2,kka2_1:1,P00552,0.999943,NO,50,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-0.833,-0.833,,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.520039,0.00138626,0.999943 kka2_1:1_L92L,kka2_1:1_92,Kka2,kka2_1:1,P00552,0.999943,NO,92,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.893,-0.893,,,0.007,E,B,0.55,-0.19,1.447,,63.26,HHH,-0.962,0.520039,0.00307177,0.999943 kka2_1:1_W69W,kka2_1:1_69,Kka2,kka2_1:1,P00552,0.999943,NO,69,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-0.859,-0.859,,,0.164,H,A,0.47,0.15,5.074,,38.64,PHH,-1.49967,0.520039,0.0012874,0.999943 kka2_1:4_G6P,kka2_1:4_6,Kka2,kka2_1:4,P00552,0.999943,NO,6,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.685,-2.187,0.502,,,,,,,,,71.59,AOH,-1.639,0.168804,0.00204693,0.999943 kka2_1:4_N58N,kka2_1:4_58,Kka2,kka2_1:4,P00552,0.999943,NO,58,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-2.641,-2.641,,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.168804,0.00793425,0.999943 beta-lactamase_156_S283W,beta-lactamase_156_283,TEM-1,beta-lactamase_156,P62593,0.999945,NO,283,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.111618,0.0429138,0.999945 beta-lactamase_39_L150H,beta-lactamase_39_150,TEM-1,beta-lactamase_39,P62593,0.999945,NO,150,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.326,-4.935,3.609,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.0495842,0.00463171,0.999945 kka2_1:2_F256F,kka2_1:2_256,Kka2,kka2_1:2,P00552,0.999946,NO,256,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.49,-1.49,,,,H,A,0.58,-0.78,1.653,,53.03,HHH,-1.423,0.295029,0.0132841,0.999946 beta-lactamase_156_G236C,beta-lactamase_156_236,TEM-1,beta-lactamase_156,P62593,0.99995,NO,236,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.784,-4.991,4.207,,0.241,,b,0.29,-0.59,1.883,,64.69,HOO,-1.025,0.111618,0.00162372,0.99995 kka2_1:2_R145R,kka2_1:2_145,Kka2,kka2_1:2,P00552,0.99995,NO,145,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.804,-1.804,,,0.346,H,A,1.2,1.23,7.961,,63.64,HBP,-1.88033,0.295029,0.00846663,0.99995 kka2_1:4_P98P,kka2_1:4_98,Kka2,kka2_1:4,P00552,0.99995,NO,98,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.526,-1.526,,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.168804,0.00622754,0.99995 kka2_1:8_A229A,kka2_1:8_229,Kka2,kka2_1:8,P00552,0.999951,NO,229,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.739,-1.739,,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.100394,0.00942138,0.999951 kka2_1:8_A229A,kka2_1:8_229,Kka2,kka2_1:8,P00552,0.999951,NO,229,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.739,-1.739,,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.100394,0.00942138,0.999951 kka2_1:8_R122R,kka2_1:8_122,Kka2,kka2_1:8,P00552,0.999951,NO,122,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.175,-2.175,,,0.487,H,A,1.2,0.26,22.675,22.675,71.59,BBH,-1.53833,0.100394,0.00736512,0.999951 kka2_1:8_R122R,kka2_1:8_122,Kka2,kka2_1:8,P00552,0.999951,NO,122,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.175,-2.175,,,0.487,H,A,1.2,0.26,22.675,22.675,71.59,BBH,-1.53833,0.100394,0.00736512,0.999951 kka2_1:1_F48F,kka2_1:1_48,Kka2,kka2_1:1,P00552,0.999952,NO,48,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.453,-1.453,,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.520039,0.00475422,0.999952 kka2_1:1_H124H,kka2_1:1_124,Kka2,kka2_1:1,P00552,0.999952,NO,124,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-0.84,-0.84,,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.520039,0.00211296,0.999952 beta-lactamase_156_G141F,beta-lactamase_156_141,TEM-1,beta-lactamase_156,P62593,0.999954,NO,141,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.828,-4.352,3.524,,0.575,T,l,0.29,-0.28,0.198,,64.69,HOO,-1.08933,0.111618,0.0012419,0.999954 Pab1_K166K,Pab1_166,Pab1,Pab1,P04147,0.999954,NO,166,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.262,-1.262,,,0.299,,l,,0,,,,PBO,-1.21033,0.175299,0.0011038,0.999954 beta-lactamase_39_L79M,beta-lactamase_39_79,TEM-1,beta-lactamase_39,P62593,0.999956,NO,79,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.842,-2.761,1.919,,0.007,H,A,0.55,-0.16,0.823,,50.35,HHP,-1.44333,0.0495842,0.000947397,0.999956 beta-lactamase_39_E195P,beta-lactamase_39_195,TEM-1,beta-lactamase_39,P62593,0.999958,NO,195,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.186,-2.83,0.644,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.0495842,0.00496565,0.999958 beta-lactamase_2500_Q88A,beta-lactamase_2500_88,TEM-1,beta-lactamase_2500,P62593,0.999964,NO,88,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.086,-2.75,0.664,,0.807,,B,0.64,2.03,1.84,,77.62,APH,-1.53433,0.361275,0.00504167,0.999964 beta-lactamase_39_P165G,beta-lactamase_39_165,TEM-1,beta-lactamase_39,P62593,0.999965,NO,165,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.373,-3.429,2.056,,0.203,T,A,0.52,-0.31,3.907,,73.78,AOA,-1.359,0.0495842,0.00549538,0.999965 kka2_1:2_A64A,kka2_1:2_64,Kka2,kka2_1:2,P00552,0.999965,NO,64,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.496,-1.496,,,0.039,H,A,0.46,-0.57,14.509,14.509,56.06,AHH,-1.334,0.295029,0.00705578,0.999965 kka2_1:8_L152L,kka2_1:8_152,Kka2,kka2_1:8,P00552,0.999967,NO,152,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.521,-1.521,,,0.547,.,A,0.55,1.36,1.442,,63.64,OHH,-1.162,0.100394,0.00674868,0.999967 kka2_1:8_L152L,kka2_1:8_152,Kka2,kka2_1:8,P00552,0.999967,NO,152,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.521,-1.521,,,0.547,.,A,0.55,1.36,1.442,,63.64,OHH,-1.162,0.100394,0.00674868,0.999967 PSD95pdz3_Q384V,PSD95pdz3_384,PSD95pdz3,PSD95pdz3,P31016,0.999967,NO,384,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-1.699,-3.21,1.511,5.49339,,,,,23.54,,,,OPP,-1.41333,0.0758425,0.000216736,0.999967 beta-lactamase_625_M153K,beta-lactamase_625_153,TEM-1,beta-lactamase_625,P62593,0.999968,NO,153,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-3.193,-3.777,0.584,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.213352,0.00509109,0.999968 kka2_1:1_F171F,kka2_1:1_171,Kka2,kka2_1:1,P00552,0.999969,NO,171,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.326,-1.326,,,0.154,H,A,1.62,-0.1,13.679,13.679,63.64,HHH,-1.45433,0.520039,0.00821426,0.999969 kka2_1:1_Q252Q,kka2_1:1_252,Kka2,kka2_1:1,P00552,0.999969,NO,252,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.63,-2.63,,,0.906,H,A,0.64,0.35,1.369,,92.05,PPB,-2.20733,0.520039,0.0121001,0.999969 kka2_1:1_T51T,kka2_1:1_51,Kka2,kka2_1:1,P00552,0.999969,NO,51,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.199,-2.199,,,0.05,E,B,0.22,-0.05,3.056,,63.64,BPA,-1.76767,0.520039,0.00628861,0.999969 beta-lactamase_156_T187S,beta-lactamase_156_187,TEM-1,beta-lactamase_156,P62593,0.99997,NO,187,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.401,-2.134,0.733,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.111618,0.00491782,0.99997 beta-lactamase_625_T269L,beta-lactamase_625_269,TEM-1,beta-lactamase_625,P62593,0.999976,NO,269,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.213352,0.00950944,0.999976 beta-lactamase_156_P25E,beta-lactamase_156_25,TEM-1,beta-lactamase_156,P62593,0.999978,NO,25,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.526,-2.543,1.017,,0.624,H,A,0.52,0.14,1.079,,73.08,BOA,-2.15367,0.111618,0.00347571,0.999978 beta-lactamase_N50S,beta-lactamase_50,TEM-1,beta-lactamase,P62593,0.99998,NO,50,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-2.979,-3.331,0.352,5.51261,0.912,T,A,1.07,1.24,1.581,,77.62,HPP,-2.134,0.221079,0.0047211,0.99998 beta-lactamase_625_Q203M,beta-lactamase_625_203,TEM-1,beta-lactamase_625,P62593,0.999981,NO,203,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.168,-4.659,2.491,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.213352,0.00631514,0.999981 beta-lactamase_625_Q267W,beta-lactamase_625_267,TEM-1,beta-lactamase_625,P62593,0.999983,NO,267,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.213352,0.0102128,0.999983 beta-lactamase_39_L160S,beta-lactamase_39_160,TEM-1,beta-lactamase_39,P62593,0.999984,NO,160,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.977,-3.653,2.676,,0.022,,B,0.55,-0.6,0.895,,44.41,BHA,-0.936,0.0495842,0.00193775,0.999984 beta-lactamase_625_T193I,beta-lactamase_625_193,TEM-1,beta-lactamase_625,P62593,0.999984,NO,193,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.914,-2.798,0.884,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.213352,0.00482669,0.999984 kka2_1:8_L81L,kka2_1:8_81,Kka2,kka2_1:8,P00552,0.999984,NO,81,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.427,-1.427,,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.100394,0.00805839,0.999984 kka2_1:8_L81L,kka2_1:8_81,Kka2,kka2_1:8,P00552,0.999984,NO,81,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.427,-1.427,,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.100394,0.00805839,0.999984 kka2_1:8_R202R,kka2_1:8_202,Kka2,kka2_1:8,P00552,0.999984,NO,202,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.761,-1.761,,,0.607,E,B,1.2,0.48,1.409,,52.27,OBH,-1.41067,0.100394,0.00696498,0.999984 kka2_1:8_R202R,kka2_1:8_202,Kka2,kka2_1:8,P00552,0.999984,NO,202,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.761,-1.761,,,0.607,E,B,1.2,0.48,1.409,,52.27,OBH,-1.41067,0.100394,0.00696498,0.999984 beta-lactamase_156_A230M,beta-lactamase_156_230,TEM-1,beta-lactamase_156,P62593,0.999985,NO,230,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.154,-4.69,3.536,,0.01,E,B,0.46,-1.17,2.179,,50,HHA,-1.079,0.111618,0.00516841,0.999985 beta-lactamase_39_E175D,beta-lactamase_39_175,TEM-1,beta-lactamase_39,P62593,0.999985,NO,175,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.336,-2.916,0.58,,0.551,,A,1.04,1.05,3.676,,77.62,AAB,-1.31233,0.0495842,0.00482205,0.999985 beta-lactamase_625_W163N,beta-lactamase_625_163,TEM-1,beta-lactamase_625,P62593,0.999985,NO,163,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-1.843,-2.852,1.009,,0.467,,B,0.47,-0.5,5.019,,63.99,BHA,-1.269,0.213352,0.00418955,0.999985 kka2_1:1_S32S,kka2_1:1_32,Kka2,kka2_1:1,P00552,0.999986,NO,32,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-0.804,-0.804,,,0.768,S,b,0.27,3.75,,,,OPA,-1.74533,0.520039,0.00149998,0.999986 beta-lactamase_625_S57R,beta-lactamase_625_57,TEM-1,beta-lactamase_625,P62593,0.999987,NO,57,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.918,-3.069,1.151,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.213352,0.00492804,0.999987 beta-lactamase_156_N134H,beta-lactamase_156_134,TEM-1,beta-lactamase_156,P62593,0.999988,NO,134,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-0.879,-4.073,3.194,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.111618,0.000644786,0.999988 beta-lactamase_156_N274V,beta-lactamase_156_274,TEM-1,beta-lactamase_156,P62593,0.999993,NO,274,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.111618,0.0110418,0.999993 beta-lactamase_2500_A84E,beta-lactamase_2500_84,TEM-1,beta-lactamase_2500,P62593,0.999993,NO,84,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.651,-2.632,0.981,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.361275,0.00503822,0.999993 beta-lactamase_39_A211E,beta-lactamase_39_211,TEM-1,beta-lactamase_39,P62593,0.999993,NO,211,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.896,-2.447,0.551,,0.369,T,A,0.46,-0.69,1.419,,77.62,AHA,-1.94633,0.0495842,0.00648183,0.999993 kka2_1:4_V153V,kka2_1:4_153,Kka2,kka2_1:4,P00552,0.999996,NO,153,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.092,-1.092,,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.168804,0.00501119,0.999996 beta-lactamase_156_D271S,beta-lactamase_156_271,TEM-1,beta-lactamase_156,P62593,1,NO,271,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.111618,0.00752082,1 hsp90_Q582Q,hsp90_582,hsp90,hsp90,P02829,1,NO,582,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-3.278,-3.278,,4.91603,0.453,S,B,,0.67,,,,OPH,-3.249,0.368192,0.000222939,1 kka2_1:1_D82D,kka2_1:1_82,Kka2,kka2_1:1,P00552,1,NO,82,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.946,-1.946,,,0.341,E,b,0.75,0.52,11.345,11.345,63.64,HAH,-1.98,0.520039,0.00637516,1 kka2_1:1_P45P,kka2_1:1_45,Kka2,kka2_1:1,P00552,1,NO,45,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.774,-1.774,,,0.669,.,B,0.52,-0.76,4.882,,71.59,BOH,-2.152,0.520039,0.00590481,1 kka2_1:2_H162H,kka2_1:2_162,Kka2,kka2_1:2,P00552,1,NO,162,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-2.319,-2.319,,,0.071,G,A,0.17,1.01,3.187,,64.39,ABP,-2.02067,0.295029,0.00616145,1 kka2_1:4_I141I,kka2_1:4_141,Kka2,kka2_1:4,P00552,1,NO,141,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.495,-1.495,,,0.068,H,A,0.48,-0.01,2.144,,92.05,BHA,-1.689,0.168804,0.00744745,1 kka2_1:8_I29I,kka2_1:8_29,Kka2,kka2_1:8,P00552,1,NO,29,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.692,-1.692,,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.100394,0.00619521,1 kka2_1:8_I29I,kka2_1:8_29,Kka2,kka2_1:8,P00552,1,NO,29,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.692,-1.692,,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.100394,0.00619521,1 Ubiquitin_D32E,Ubiquitin_32,Uba1,Ubiquitin,P0CG48,1,NO,32,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.451,-2.129,0.678,4.96502,0.835,H,A,,1.4,,,,PAB,-1.47067,0.205827,0.000758819,1 Ubiquitin_D39D,Ubiquitin_39,Uba1,Ubiquitin,P0CG48,1,NO,39,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.792,-1.792,0,5.1607,0.433,G,A,,0.55,,,,OAP,-1.754,0.205827,0.00071409,1 Ubiquitin_D52C,Ubiquitin_52,Uba1,Ubiquitin,P0CG48,1,NO,52,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.43,-5.088,3.658,4.75143,0.421,T,A,,0.79,,,,AAO,-1.50267,0.205827,0.000806517,1 Ubiquitin_D52D,Ubiquitin_52,Uba1,Ubiquitin,P0CG48,1,NO,52,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.43,-1.43,0,4.75143,0.421,T,A,,0.79,,,,AAO,-1.50267,0.205827,0.000806517,1 Ubiquitin_D52K,Ubiquitin_52,Uba1,Ubiquitin,P0CG48,1,NO,52,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.43,-3.519,2.089,4.75143,0.421,T,A,,0.79,,,,AAO,-1.50267,0.205827,0.000806517,1 Ubiquitin_D52R,Ubiquitin_52,Uba1,Ubiquitin,P0CG48,1,NO,52,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.43,-3.906,2.476,4.75143,0.421,T,A,,0.79,,,,AAO,-1.50267,0.205827,0.000806517,1 Ubiquitin_D58D,Ubiquitin_58,Uba1,Ubiquitin,P0CG48,1,NO,58,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.622,-1.622,0,5.06391,0.457,G,A,,-0.54,,,,PAH,-1.60267,0.205827,0.000639847,1 Ubiquitin_E16E,Ubiquitin_16,Uba1,Ubiquitin,P0CG48,1,NO,16,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.545,-1.545,,5.07465,0.567,E,B,,0.59,,,,HAH,-1.31367,0.205827,0.000786769,1 Ubiquitin_E16P,Ubiquitin_16,Uba1,Ubiquitin,P0CG48,1,NO,16,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.545,-3.78,2.235,5.07465,0.567,E,B,,0.59,,,,HAH,-1.31367,0.205827,0.000786769,1 Ubiquitin_E16Q,Ubiquitin_16,Uba1,Ubiquitin,P0CG48,1,NO,16,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.545,-3.55,2.005,5.07465,0.567,E,B,,0.59,,,,HAH,-1.31367,0.205827,0.000786769,1 Ubiquitin_E16S,Ubiquitin_16,Uba1,Ubiquitin,P0CG48,1,NO,16,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.545,-3.207,1.662,5.07465,0.567,E,B,,0.59,,,,HAH,-1.31367,0.205827,0.000786769,1 Ubiquitin_E18C,Ubiquitin_18,Uba1,Ubiquitin,P0CG48,1,NO,18,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.696,-5.127,3.431,5.04795,0.545,,B,,0.03,,,,HAO,-1.78733,0.205827,0.000623342,1 Ubiquitin_E18E,Ubiquitin_18,Uba1,Ubiquitin,P0CG48,1,NO,18,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.696,-1.696,,5.04795,0.545,,B,,0.03,,,,HAO,-1.78733,0.205827,0.000623342,1 Ubiquitin_E18G,Ubiquitin_18,Uba1,Ubiquitin,P0CG48,1,NO,18,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.696,-3.444,1.748,5.04795,0.545,,B,,0.03,,,,HAO,-1.78733,0.205827,0.000623342,1 Ubiquitin_E18R,Ubiquitin_18,Uba1,Ubiquitin,P0CG48,1,NO,18,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.696,-3.768,2.072,5.04795,0.545,,B,,0.03,,,,HAO,-1.78733,0.205827,0.000623342,1 Ubiquitin_E34E,Ubiquitin_34,Uba1,Ubiquitin,P0CG48,1,NO,34,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.294,-1.294,0,5.02178,0.406,H,A,1.62,0.6,1.295,,35.62,BAO,-1.24933,0.205827,0.000686048,1 Ubiquitin_E34G,Ubiquitin_34,Uba1,Ubiquitin,P0CG48,1,NO,34,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.294,-2.523,1.229,5.02178,0.406,H,A,1.62,0.6,1.295,,35.62,BAO,-1.24933,0.205827,0.000686048,1 Ubiquitin_E51E,Ubiquitin_51,Uba1,Ubiquitin,P0CG48,1,NO,51,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.534,-1.534,0,5.36711,0.545,,B,,0.72,,,,HAA,-1.357,0.205827,0.000868134,1 Ubiquitin_E51N,Ubiquitin_51,Uba1,Ubiquitin,P0CG48,1,NO,51,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.534,-3.558,2.024,5.36711,0.545,,B,,0.72,,,,HAA,-1.357,0.205827,0.000868134,1 Ubiquitin_E64C,Ubiquitin_64,Uba1,Ubiquitin,P0CG48,1,NO,64,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.763,-3.397,1.634,5.084,0.54,T,l,,0.79,,,,BAP,-1.64433,0.205827,0.000817406,1 Ubiquitin_E64E,Ubiquitin_64,Uba1,Ubiquitin,P0CG48,1,NO,64,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.763,-1.763,0,5.084,0.54,T,l,,0.79,,,,BAP,-1.64433,0.205827,0.000817406,1 Ubiquitin_F45A,Ubiquitin_45,Uba1,Ubiquitin,P0CG48,1,NO,45,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.322,-3.268,1.946,4.80693,0.26,E,B,1.62,-0.99,1.531,,53.87,HHH,-1.55267,0.205827,0.000470401,1 Ubiquitin_G53W,Ubiquitin_53,Uba1,Ubiquitin,P0CG48,1,NO,53,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.544,-5.277,3.733,5.32628,0.805,T,A,,-0.23,,,,AOB,-1.67033,0.205827,0.000662865,1 Ubiquitin_G53Y,Ubiquitin_53,Uba1,Ubiquitin,P0CG48,1,NO,53,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.544,-3.069,1.525,5.32628,0.805,T,A,,-0.23,,,,AOB,-1.67033,0.205827,0.000662865,1 Ubiquitin_I13I,Ubiquitin_13,Uba1,Ubiquitin,P0CG48,1,NO,13,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.554,-1.554,,5.19411,0.038,E,B,,-0.2,,,,PHP,-1.48,0.205827,0.000716423,1 Ubiquitin_I23L,Ubiquitin_23,Uba1,Ubiquitin,P0CG48,1,NO,23,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.325,-2.653,1.328,4.67534,,H,A,0.01,-0.93,0.515,,52.12,PHA,-1.54033,0.205827,0.000621252,1 Ubiquitin_I30I,Ubiquitin_30,Uba1,Ubiquitin,P0CG48,1,NO,30,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.205,-1.205,0,4.80264,,H,A,,-0.51,,,,BHP,-1.45133,0.205827,0.000720128,1 Ubiquitin_I30V,Ubiquitin_30,Uba1,Ubiquitin,P0CG48,1,NO,30,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.205,-2.125,0.92,4.80264,,H,A,,-0.51,,,,BHP,-1.45133,0.205827,0.000720128,1 Ubiquitin_I36I,Ubiquitin_36,Uba1,Ubiquitin,P0CG48,1,NO,36,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.477,-1.477,0,5.1035,0.203,,B,0.27,-0.22,1.552,,30.8,OHO,-1.30767,0.205827,0.000630555,1 Ubiquitin_I36L,Ubiquitin_36,Uba1,Ubiquitin,P0CG48,1,NO,36,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.477,-2.296,0.819,5.1035,0.203,,B,0.27,-0.22,1.552,,30.8,OHO,-1.30767,0.205827,0.000630555,1 Ubiquitin_I36V,Ubiquitin_36,Uba1,Ubiquitin,P0CG48,1,NO,36,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.477,-2.136,0.659,5.1035,0.203,,B,0.27,-0.22,1.552,,30.8,OHO,-1.30767,0.205827,0.000630555,1 Ubiquitin_I3L,Ubiquitin_3,Uba1,Ubiquitin,P0CG48,1,NO,3,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.402,-2.025,0.623,4.80819,,E,B,,-0.78,,,,PHH,-1.54533,0.205827,0.000836911,1 Ubiquitin_I3M,Ubiquitin_3,Uba1,Ubiquitin,P0CG48,1,NO,3,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.402,-4.119,2.717,4.80819,,E,B,,-0.78,,,,PHH,-1.54533,0.205827,0.000836911,1 Ubiquitin_I61V,Ubiquitin_61,Uba1,Ubiquitin,P0CG48,1,NO,61,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.514,-2.122,0.608,5.19922,0.038,,B,1,-0.76,1.953,,24.53,PHP,-1.70833,0.205827,0.000738268,1 Ubiquitin_K29C,Ubiquitin_29,Uba1,Ubiquitin,P0CG48,1,NO,29,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.471,-5.123,3.652,4.74832,0.355,H,A,,-0.06,,,,HBH,-1.52367,0.205827,0.000900239,1 Ubiquitin_K29K,Ubiquitin_29,Uba1,Ubiquitin,P0CG48,1,NO,29,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.471,-1.471,0,4.74832,0.355,H,A,,-0.06,,,,HBH,-1.52367,0.205827,0.000900239,1 Ubiquitin_K29Q,Ubiquitin_29,Uba1,Ubiquitin,P0CG48,1,NO,29,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.471,-2.619,1.148,4.74832,0.355,H,A,,-0.06,,,,HBH,-1.52367,0.205827,0.000900239,1 Ubiquitin_K63K,Ubiquitin_63,Uba1,Ubiquitin,P0CG48,1,NO,63,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.635,-1.635,0,5.08297,0.721,T,B,,0.59,,,,PBA,-1.74467,0.205827,0.000607964,1 Ubiquitin_L15C,Ubiquitin_15,Uba1,Ubiquitin,P0CG48,1,NO,15,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.082,-4.663,3.581,5.14718,0.029,E,B,1.16,-0.53,0.936,,38.69,PHA,-1.40833,0.205827,0.000519738,1 Ubiquitin_L15I,Ubiquitin_15,Uba1,Ubiquitin,P0CG48,1,NO,15,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.082,-2.114,1.032,5.14718,0.029,E,B,1.16,-0.53,0.936,,38.69,PHA,-1.40833,0.205827,0.000519738,1 Ubiquitin_L43M,Ubiquitin_43,Uba1,Ubiquitin,P0CG48,1,NO,43,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.269,-2.957,1.688,4.8799,,E,B,1.75,-1.17,10.246,10.246,53.87,BHH,-1.46867,0.205827,0.000572481,1 Ubiquitin_L56L,Ubiquitin_56,Uba1,Ubiquitin,P0CG48,1,NO,56,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.324,-1.324,0,4.83362,,T,A,,-0.91,,,,PHP,-1.60067,0.205827,0.000459465,1 Ubiquitin_L56V,Ubiquitin_56,Uba1,Ubiquitin,P0CG48,1,NO,56,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.324,-2.271,0.947,4.83362,,T,A,,-0.91,,,,PHP,-1.60067,0.205827,0.000459465,1 Ubiquitin_L67C,Ubiquitin_67,Uba1,Ubiquitin,P0CG48,1,NO,67,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.435,-4.858,3.423,4.92156,,E,B,1.19,-1.02,6.371,6.371,30.8,PHB,-1.628,0.205827,0.000482727,1 Ubiquitin_N25D,Ubiquitin_25,Uba1,Ubiquitin,P0CG48,1,NO,25,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-1.95,-2.375,0.425,4.76563,0.444,H,A,0.09,0,2.3,,31.09,APH,-1.741,0.205827,0.00071919,1 Ubiquitin_N60N,Ubiquitin_60,Uba1,Ubiquitin,P0CG48,1,NO,60,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-1.775,-1.775,0,5.00332,0.775,T,L,,0.33,,,,HPH,-1.532,0.205827,0.000814061,1 Ubiquitin_P19A,Ubiquitin_19,Uba1,Ubiquitin,P0CG48,1,NO,19,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-2.352,-2.306,-0.046,4.67617,0.398,T,A,,-0.61,,,,AOP,-1.86233,0.205827,0.000729653,1 Ubiquitin_P19H,Ubiquitin_19,Uba1,Ubiquitin,P0CG48,1,NO,19,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-2.352,-4.711,2.359,4.67617,0.398,T,A,,-0.61,,,,AOP,-1.86233,0.205827,0.000729653,1 Ubiquitin_P19N,Ubiquitin_19,Uba1,Ubiquitin,P0CG48,1,NO,19,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-2.352,-2.991,0.639,4.67617,0.398,T,A,,-0.61,,,,AOP,-1.86233,0.205827,0.000729653,1 Ubiquitin_P19S,Ubiquitin_19,Uba1,Ubiquitin,P0CG48,1,NO,19,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-2.352,-2.29,-0.062,4.67617,0.398,T,A,,-0.61,,,,AOP,-1.86233,0.205827,0.000729653,1 Ubiquitin_P19T,Ubiquitin_19,Uba1,Ubiquitin,P0CG48,1,NO,19,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-2.352,-2.841,0.489,4.67617,0.398,T,A,,-0.61,,,,AOP,-1.86233,0.205827,0.000729653,1 Ubiquitin_P37D,Ubiquitin_37,Uba1,Ubiquitin,P0CG48,1,NO,37,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.275,-3.599,2.324,5.06918,0.323,,B,,-0.09,,,,HOO,-1.49,0.205827,0.000600764,1 Ubiquitin_P37E,Ubiquitin_37,Uba1,Ubiquitin,P0CG48,1,NO,37,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.275,-3.508,2.233,5.06918,0.323,,B,,-0.09,,,,HOO,-1.49,0.205827,0.000600764,1 Ubiquitin_P37M,Ubiquitin_37,Uba1,Ubiquitin,P0CG48,1,NO,37,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.275,-4.598,3.323,5.06918,0.323,,B,,-0.09,,,,HOO,-1.49,0.205827,0.000600764,1 Ubiquitin_P37P,Ubiquitin_37,Uba1,Ubiquitin,P0CG48,1,NO,37,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.275,-1.275,0,5.06918,0.323,,B,,-0.09,,,,HOO,-1.49,0.205827,0.000600764,1 Ubiquitin_P38F,Ubiquitin_38,Uba1,Ubiquitin,P0CG48,1,NO,38,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.718,-3.125,1.407,5.0146,0.316,G,A,,-0.52,,,,OOA,-1.595,0.205827,0.000781418,1 Ubiquitin_P38N,Ubiquitin_38,Uba1,Ubiquitin,P0CG48,1,NO,38,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.718,-2.989,1.271,5.0146,0.316,G,A,,-0.52,,,,OOA,-1.595,0.205827,0.000781418,1 Ubiquitin_P38P,Ubiquitin_38,Uba1,Ubiquitin,P0CG48,1,NO,38,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.718,-1.718,0,5.0146,0.316,G,A,,-0.52,,,,OOA,-1.595,0.205827,0.000781418,1 Ubiquitin_P38W,Ubiquitin_38,Uba1,Ubiquitin,P0CG48,1,NO,38,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.718,-5.408,3.69,5.0146,0.316,G,A,,-0.52,,,,OOA,-1.595,0.205827,0.000781418,1 Ubiquitin_P38Y,Ubiquitin_38,Uba1,Ubiquitin,P0CG48,1,NO,38,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.718,-4.151,2.433,5.0146,0.316,G,A,,-0.52,,,,OOA,-1.595,0.205827,0.000781418,1 Ubiquitin_Q2Q,Ubiquitin_2,Uba1,Ubiquitin,P0CG48,1,NO,2,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-1.7,-1.7,,4.89203,0.475,E,B,,0.1,,,,OPH,-1.551,0.205827,0.00085006,1 Ubiquitin_Q62A,Ubiquitin_62,Uba1,Ubiquitin,P0CG48,1,NO,62,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-1.836,-3.2,1.364,5.33616,0.762,,B,,0.79,,,,HPB,-1.66167,0.205827,0.00068944,1 Ubiquitin_Q62G,Ubiquitin_62,Uba1,Ubiquitin,P0CG48,1,NO,62,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-1.836,-2.763,0.927,5.33616,0.762,,B,,0.79,,,,HPB,-1.66167,0.205827,0.00068944,1 Ubiquitin_Q62K,Ubiquitin_62,Uba1,Ubiquitin,P0CG48,1,NO,62,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-1.836,-2.556,0.72,5.33616,0.762,,B,,0.79,,,,HPB,-1.66167,0.205827,0.00068944,1 Ubiquitin_Q62M,Ubiquitin_62,Uba1,Ubiquitin,P0CG48,1,NO,62,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-1.836,-4.612,2.776,5.33616,0.762,,B,,0.79,,,,HPB,-1.66167,0.205827,0.00068944,1 Ubiquitin_Q62Q,Ubiquitin_62,Uba1,Ubiquitin,P0CG48,1,NO,62,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-1.836,-1.836,0,5.33616,0.762,,B,,0.79,,,,HPB,-1.66167,0.205827,0.00068944,1 Ubiquitin_Q62Y,Ubiquitin_62,Uba1,Ubiquitin,P0CG48,1,NO,62,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-1.836,-4.279,2.443,5.33616,0.762,,B,,0.79,,,,HPB,-1.66167,0.205827,0.00068944,1 Ubiquitin_R54A,Ubiquitin_54,Uba1,Ubiquitin,P0CG48,1,NO,54,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.037,-3.248,1.211,5.14935,0.41,S,B,,0.87,,,,OBP,-1.72667,0.205827,0.000581095,1 Ubiquitin_R54P,Ubiquitin_54,Uba1,Ubiquitin,P0CG48,1,NO,54,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.037,-3.001,0.964,5.14935,0.41,S,B,,0.87,,,,OBP,-1.72667,0.205827,0.000581095,1 Ubiquitin_R72R,Ubiquitin_72,Uba1,Ubiquitin,P0CG48,1,NO,72,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.034,-2.034,0,5.19484,0.077,,B,1.41,-0.1,9.638,9.638,42.77,HBH,-1.82733,0.205827,0.000768249,1 Ubiquitin_R74R,Ubiquitin_74,Uba1,Ubiquitin,P0CG48,1,NO,74,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.739,-1.739,0,5.6462,0.838,T,A,0.98,3.15,9.119,9.119,34.31,HBO,-1.71767,0.205827,0.000894236,1 Ubiquitin_S20I,Ubiquitin_20,Uba1,Ubiquitin,P0CG48,1,NO,20,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.539,-3.949,2.41,5.15339,0.672,T,A,,-0.6,,,,OPA,-1.69467,0.205827,0.000670478,1 Ubiquitin_S20N,Ubiquitin_20,Uba1,Ubiquitin,P0CG48,1,NO,20,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.539,-2.465,0.926,5.15339,0.672,T,A,,-0.6,,,,OPA,-1.69467,0.205827,0.000670478,1 Ubiquitin_S20S,Ubiquitin_20,Uba1,Ubiquitin,P0CG48,1,NO,20,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.539,-1.539,,5.15339,0.672,T,A,,-0.6,,,,OPA,-1.69467,0.205827,0.000670478,1 Ubiquitin_S20V,Ubiquitin_20,Uba1,Ubiquitin,P0CG48,1,NO,20,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.539,-3.588,2.049,5.15339,0.672,T,A,,-0.6,,,,OPA,-1.69467,0.205827,0.000670478,1 Ubiquitin_S20Y,Ubiquitin_20,Uba1,Ubiquitin,P0CG48,1,NO,20,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.539,-4.307,2.768,5.15339,0.672,T,A,,-0.6,,,,OPA,-1.69467,0.205827,0.000670478,1 Ubiquitin_S57A,Ubiquitin_57,Uba1,Ubiquitin,P0CG48,1,NO,57,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.879,-2.113,0.234,4.65125,0.456,G,A,,-0.42,,,,HPA,-1.60833,0.205827,0.000948086,1 Ubiquitin_S57G,Ubiquitin_57,Uba1,Ubiquitin,P0CG48,1,NO,57,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.879,-2.699,0.82,4.65125,0.456,G,A,,-0.42,,,,HPA,-1.60833,0.205827,0.000948086,1 Ubiquitin_S57I,Ubiquitin_57,Uba1,Ubiquitin,P0CG48,1,NO,57,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.879,-2.961,1.082,4.65125,0.456,G,A,,-0.42,,,,HPA,-1.60833,0.205827,0.000948086,1 Ubiquitin_S57K,Ubiquitin_57,Uba1,Ubiquitin,P0CG48,1,NO,57,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.879,-2.851,0.972,4.65125,0.456,G,A,,-0.42,,,,HPA,-1.60833,0.205827,0.000948086,1 Ubiquitin_S57M,Ubiquitin_57,Uba1,Ubiquitin,P0CG48,1,NO,57,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.879,-4.545,2.666,4.65125,0.456,G,A,,-0.42,,,,HPA,-1.60833,0.205827,0.000948086,1 Ubiquitin_T14S,Ubiquitin_14,Uba1,Ubiquitin,P0CG48,1,NO,14,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.598,-2.446,0.848,5.10811,0.345,E,B,,-0.37,,,,HPH,-1.41133,0.205827,0.000632754,1 Ubiquitin_T14T,Ubiquitin_14,Uba1,Ubiquitin,P0CG48,1,NO,14,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.598,-1.598,,5.10811,0.345,E,B,,-0.37,,,,HPH,-1.41133,0.205827,0.000632754,1 Ubiquitin_T55C,Ubiquitin_55,Uba1,Ubiquitin,P0CG48,1,NO,55,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.599,-4.928,3.329,4.58329,0.173,B,B,,-0.68,,,,BPH,-1.65333,0.205827,0.000525703,1 Ubiquitin_T55K,Ubiquitin_55,Uba1,Ubiquitin,P0CG48,1,NO,55,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.599,-2.885,1.286,4.58329,0.173,B,B,,-0.68,,,,BPH,-1.65333,0.205827,0.000525703,1 Ubiquitin_T55N,Ubiquitin_55,Uba1,Ubiquitin,P0CG48,1,NO,55,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.599,-2.951,1.352,4.58329,0.173,B,B,,-0.68,,,,BPH,-1.65333,0.205827,0.000525703,1 Ubiquitin_T55T,Ubiquitin_55,Uba1,Ubiquitin,P0CG48,1,NO,55,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.599,-1.599,0,4.58329,0.173,B,B,,-0.68,,,,BPH,-1.65333,0.205827,0.000525703,1 Ubiquitin_T66N,Ubiquitin_66,Uba1,Ubiquitin,P0CG48,1,NO,66,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.58,-3.745,2.165,5.02702,0.46,E,B,0.8,-0.81,28.36,28.36,39.71,PPH,-1.51667,0.205827,0.000598414,1 Ubiquitin_T7T,Ubiquitin_7,Uba1,Ubiquitin,P0CG48,1,NO,7,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.415,-1.415,,4.954,0.094,E,B,0.43,-0.78,0.805,,21.31,BPH,-1.41033,0.205827,0.000647855,1 Ubiquitin_V17V,Ubiquitin_17,Uba1,Ubiquitin,P0CG48,1,NO,17,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.314,-1.314,,5.26282,0.017,,B,2.78,-0.77,3.239,,71.82,AHA,-1.51833,0.205827,0.000659638,1 Ubiquitin_Y59Y,Ubiquitin_59,Uba1,Ubiquitin,P0CG48,1,NO,59,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-1.307,-1.307,0,5.05599,0.072,G,A,0.43,-0.74,2.566,,24.53,AHP,-1.568,0.205827,0.000775084,1 beta-lactamase_39_K190W,beta-lactamase_39_190,TEM-1,beta-lactamase_39,P62593,1.00001,NO,190,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.994,-5.522,3.528,,0.371,H,A,2.34,0.16,1.513,,77.62,BBH,-1.64167,0.0495842,0.00574527,1.00001 beta-lactamase_39_T263I,beta-lactamase_39_263,TEM-1,beta-lactamase_39,P62593,1.00001,NO,263,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.0495842,0.0110582,1.00001 beta-lactamase_625_A133S,beta-lactamase_625_133,TEM-1,beta-lactamase_625,P62593,1.00001,NO,133,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.186,-3.092,1.906,,,H,A,0.46,-0.86,0.373,,67.83,HHP,-0.988333,0.213352,0.00468022,1.00001 beta-lactamase_625_A268D,beta-lactamase_625_268,TEM-1,beta-lactamase_625,P62593,1.00001,NO,268,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.213352,0.0102525,1.00001 kka2_1:1_I246I,kka2_1:1_246,Kka2,kka2_1:1,P00552,1.00001,NO,246,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-2.008,-2.008,,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.520039,0.0139479,1.00001 kka2_1:1_L19L,kka2_1:1_19,Kka2,kka2_1:1,P00552,1.00001,NO,19,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.254,-1.254,,,0.08,T,A,0.55,-0.26,17.165,17.165,65.53,BHH,-2.221,0.520039,0.00620703,1.00001 kka2_1:1_R89R,kka2_1:1_89,Kka2,kka2_1:1,P00552,1.00001,NO,89,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.548,-1.548,,,0.209,E,B,0.16,1.41,14.396,14.396,64.39,OBA,-1.89867,0.520039,0.00524373,1.00001 kka2_1:1_S204S,kka2_1:1_204,Kka2,kka2_1:1,P00552,1.00001,NO,204,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.353,-1.353,,,0.144,E,A,0.27,-1.2,3.022,,65.53,HPO,-0.953333,0.520039,0.00881794,1.00001 kka2_1:1_V84V,kka2_1:1_84,Kka2,kka2_1:1,P00552,1.00001,NO,84,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-2.279,-2.279,,,0.258,E,B,0.44,1.03,3.484,,71.59,HHP,-2.337,0.520039,0.00724019,1.00001 kka2_1:2_D134D,kka2_1:2_134,Kka2,kka2_1:2,P00552,1.00001,NO,134,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.969,-0.969,,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.295029,0.00270812,1.00001 kka2_1:2_M120M,kka2_1:2_120,Kka2,kka2_1:2,P00552,1.00001,NO,120,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-3.877,-3.877,,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.295029,0.00265808,1.00001 beta-lactamase_39_V214N,beta-lactamase_39_214,TEM-1,beta-lactamase_39,P62593,1.00002,NO,214,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.299,-3.962,2.663,,0.375,S,A,0.44,-0.44,18.838,18.838,74.48,BHH,-1.53733,0.0495842,0.00628442,1.00002 kka2_1:2_T73T,kka2_1:2_73,Kka2,kka2_1:2,P00552,1.00002,NO,73,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.51,-2.51,,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.295029,0.00628605,1.00002 kka2_1:4_L53M,kka2_1:4_53,Kka2,kka2_1:4,P00552,1.00002,NO,53,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-2.681,-3.617,0.936,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.168804,0.00671168,1.00002 kka2_1:4_L60L,kka2_1:4_60,Kka2,kka2_1:4,P00552,1.00002,NO,60,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.997,-0.997,,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.168804,0.00262176,1.00002 kka2_1:4_S204S,kka2_1:4_204,Kka2,kka2_1:4,P00552,1.00002,NO,204,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.353,-1.353,,,0.144,E,A,0.27,-1.2,2.442,,65.53,HPO,-0.953333,0.168804,0.00881794,1.00002 beta-lactamase_625_F70H,beta-lactamase_625_70,TEM-1,beta-lactamase_625,P62593,1.00003,NO,70,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.169,-4.494,3.325,,,H,A,0.58,-1.34,1.14,,63.99,PHB,-0.980667,0.213352,0.00193499,1.00003 kka2_1:1_A64A,kka2_1:1_64,Kka2,kka2_1:1,P00552,1.00003,NO,64,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.496,-1.496,,,0.039,H,A,0.46,-0.57,1.175,,56.06,AHH,-1.334,0.520039,0.00705578,1.00003 kka2_1:1_E161E,kka2_1:1_161,Kka2,kka2_1:1,P00552,1.00003,NO,161,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.581,-1.581,,,0.829,G,A,1.04,2.24,1.612,,92.05,AAB,-1.861,0.520039,0.00760103,1.00003 kka2_1:2_L92L,kka2_1:2_92,Kka2,kka2_1:2,P00552,1.00003,NO,92,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.893,-0.893,,,0.007,E,B,1.59,-0.19,1.447,,63.26,HHH,-0.962,0.295029,0.00307177,1.00003 kka2_1:2_S204S,kka2_1:2_204,Kka2,kka2_1:2,P00552,1.00003,NO,204,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.353,-1.353,,,0.144,E,A,0.27,-1.2,2.442,,65.53,HPO,-0.953333,0.295029,0.00881794,1.00003 kka2_1:4_T51T,kka2_1:4_51,Kka2,kka2_1:4,P00552,1.00003,NO,51,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.199,-2.199,,,0.05,E,B,0.82,-0.05,13.165,13.165,63.64,BPA,-1.76767,0.168804,0.00628861,1.00003 kka2_1:8_G55G,kka2_1:8_55,Kka2,kka2_1:8,P00552,1.00003,NO,55,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.625,-1.625,,,0.517,S,b,0.29,1.19,8.881,,63.64,POH,-2.05967,0.100394,0.00667877,1.00003 kka2_1:8_G55G,kka2_1:8_55,Kka2,kka2_1:8,P00552,1.00003,NO,55,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.625,-1.625,,,0.517,S,b,0.29,1.19,8.881,,63.64,POH,-2.05967,0.100394,0.00667877,1.00003 kka2_1:8_P12P,kka2_1:8_12,Kka2,kka2_1:8,P00552,1.00003,NO,12,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.853,-0.853,,,,.,B,0.52,1.25,2.41,,48.11,POH,-1.80767,0.100394,0.00500011,1.00003 kka2_1:8_P12P,kka2_1:8_12,Kka2,kka2_1:8,P00552,1.00003,NO,12,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.853,-0.853,,,,.,B,0.52,1.25,2.41,,48.11,POH,-1.80767,0.100394,0.00500011,1.00003 kka2_1:8_P179P,kka2_1:8_179,Kka2,kka2_1:8,P00552,1.00003,NO,179,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.974,-0.974,,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.100394,0.00298346,1.00003 kka2_1:8_P179P,kka2_1:8_179,Kka2,kka2_1:8,P00552,1.00003,NO,179,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.974,-0.974,,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.100394,0.00298346,1.00003 beta-lactamase_39_G249A,beta-lactamase_39_249,TEM-1,beta-lactamase_39,P62593,1.00004,NO,249,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.312,,,,0.256,S,B,0.23,0.04,30.841,30.841,72.73,HOO,-1.81367,0.0495842,0.00220169,1.00004 beta-lactamase_625_V101A,beta-lactamase_625_101,TEM-1,beta-lactamase_625,P62593,1.00004,NO,101,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.295,-3.114,1.819,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.213352,0.00374492,1.00004 kka2_1:1_G55G,kka2_1:1_55,Kka2,kka2_1:1,P00552,1.00004,NO,55,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.625,-1.625,,,0.517,S,b,0.29,1.19,4.035,,63.64,POH,-2.05967,0.520039,0.00667877,1.00004 kka2_1:1_L165L,kka2_1:1_165,Kka2,kka2_1:1,P00552,1.00004,NO,165,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-2.453,-2.453,,,0.299,,B,1.59,1.12,2.47,,64.39,OHH,-1.90967,0.520039,0.00801161,1.00004 kka2_1:2_L103L,kka2_1:2_103,Kka2,kka2_1:2,P00552,1.00004,NO,103,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-2.362,-2.362,,,0.394,T,A,0.55,-0.99,3.499,,63.64,HHP,-1.534,0.295029,0.00574792,1.00004 beta-lactamase_156_K30F,beta-lactamase_156_30,TEM-1,beta-lactamase_156,P62593,1.00005,NO,30,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-2.307,-4.338,2.031,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.111618,0.00448593,1.00005 beta-lactamase_156_Q267P,beta-lactamase_156_267,TEM-1,beta-lactamase_156,P62593,1.00005,NO,267,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.111618,0.0102128,1.00005 beta-lactamase_2500_V78I,beta-lactamase_2500_78,TEM-1,beta-lactamase_2500,P62593,1.00005,NO,78,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.459,-1.96,0.501,,,H,A,0.44,-0.47,31.376,31.376,63.64,HHH,-1.17833,0.361275,0.00492501,1.00005 beta-lactamase_39_A133V,beta-lactamase_39_133,TEM-1,beta-lactamase_39,P62593,1.00005,NO,133,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.186,-3.341,2.155,,,H,A,0.46,-0.86,0.373,,67.83,HHP,-0.988333,0.0495842,0.00468022,1.00005 beta-lactamase_E46E,beta-lactamase_46,TEM-1,beta-lactamase,P62593,1.00005,NO,46,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.94,-1.94,,5.36461,0.021,E,B,1.51,0.14,0.373,,59.44,HAH,-2.079,0.221079,0.00427568,1.00005 kka2_1:1_D62D,kka2_1:1_62,Kka2,kka2_1:1,P00552,1.00005,NO,62,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.591,-1.591,,,0.262,H,A,0.75,0.08,10.048,10.048,64.39,PAA,-1.77833,0.520039,0.00744243,1.00005 kka2_1:1_R66R,kka2_1:1_66,Kka2,kka2_1:1,P00552,1.00005,NO,66,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-0.922,-0.922,,,0.103,H,A,1.2,-0.2,2.659,,46.21,HBH,-1.13567,0.520039,0.00161025,1.00005 kka2_1:1_T130T,kka2_1:1_130,Kka2,kka2_1:1,P00552,1.00005,NO,130,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.392,-2.392,,,0.561,G,A,0.22,0.77,0.5,,92.05,HPO,-1.62633,0.520039,0.00804204,1.00005 kka2_1:8_L107I,kka2_1:8_107,Kka2,kka2_1:8,P00552,1.00005,NO,107,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.238,-2.172,0.934,,0.197,.,B,0.55,-1.1,4.478,,71.59,BHH,-2.143,0.100394,0.00561937,1.00005 kka2_1:8_L107I,kka2_1:8_107,Kka2,kka2_1:8,P00552,1.00005,NO,107,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.238,-2.172,0.934,,0.197,.,B,0.55,-1.1,4.478,,71.59,BHH,-2.143,0.100394,0.00561937,1.00005 beta-lactamase_156_A124G,beta-lactamase_156_124,TEM-1,beta-lactamase_156,P62593,1.00006,NO,124,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.181,-3.186,2.005,,,H,A,0.46,-0.9,2.027,,64.34,HHH,-1.152,0.111618,0.00481399,1.00006 beta-lactamase_156_L89C,beta-lactamase_156_89,TEM-1,beta-lactamase_156,P62593,1.00006,NO,89,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.096,-4.756,3.66,,0.168,T,A,0.55,0.63,2.633,,64.34,PHO,-1.75767,0.111618,0.00207068,1.00006 beta-lactamase_625_L150W,beta-lactamase_625_150,TEM-1,beta-lactamase_625,P62593,1.00006,NO,150,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.326,-5.247,3.921,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.213352,0.00463171,1.00006 beta-lactamase_625_Q97I,beta-lactamase_625_97,TEM-1,beta-lactamase_625,P62593,1.00006,NO,97,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.072,-4.072,2,,0.823,G,A,0.64,2.42,16.954,16.954,77.62,PPP,-2.43833,0.213352,0.0045116,1.00006 beta-lactamase_D99D,beta-lactamase_99,TEM-1,beta-lactamase,P62593,1.00006,NO,99,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.191,-1.191,,5.66081,0.402,G,A,0.23,0.36,1.318,,64.69,PAH,-1.794,0.221079,0.00305446,1.00006 kka2_1:2_F37F,kka2_1:2_37,Kka2,kka2_1:2,P00552,1.00006,NO,37,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.427,-1.427,,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.295029,0.00586193,1.00006 kka2_1:2_L19L,kka2_1:2_19,Kka2,kka2_1:2,P00552,1.00006,NO,19,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.254,-1.254,,,0.08,T,A,0.55,-0.26,17.165,17.165,65.53,BHH,-2.221,0.295029,0.00620703,1.00006 kka2_1:1_D127D,kka2_1:1_127,Kka2,kka2_1:1,P00552,1.00007,NO,127,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.364,-1.364,,,0.573,.,B,0.75,0.45,3.414,,50.38,HAO,-1.51067,0.520039,0.00660501,1.00007 kka2_1:2_T51T,kka2_1:2_51,Kka2,kka2_1:2,P00552,1.00007,NO,51,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.199,-2.199,,,0.05,E,B,0.22,-0.05,13.165,13.165,63.64,BPA,-1.76767,0.295029,0.00628861,1.00007 kka2_1:4_P12P,kka2_1:4_12,Kka2,kka2_1:4,P00552,1.00007,NO,12,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.853,-0.853,,,,,B,0.52,1.25,0.843,,48.11,POH,-1.80767,0.168804,0.00500011,1.00007 kka2_1:4_S104S,kka2_1:4_104,Kka2,kka2_1:4,P00552,1.00007,NO,104,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.436,-1.436,,,0.536,T,A,0.27,-1.11,0.357,,63.64,HPP,-1.91433,0.168804,0.00555207,1.00007 kka2_1:8_L158L,kka2_1:8_158,Kka2,kka2_1:8,P00552,1.00007,NO,158,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.947,-1.947,,,0.095,.,B,0.55,0.77,1.607,,63.64,AHA,-1.25333,0.100394,0.00529068,1.00007 kka2_1:8_L158L,kka2_1:8_158,Kka2,kka2_1:8,P00552,1.00007,NO,158,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.947,-1.947,,,0.095,.,B,0.55,0.77,1.607,,63.64,AHA,-1.25333,0.100394,0.00529068,1.00007 beta-lactamase_156_E210N,beta-lactamase_156_210,TEM-1,beta-lactamase_156,P62593,1.00008,NO,210,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.319,-3.904,1.585,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.111618,0.00663582,1.00008 beta-lactamase_156_M184V,beta-lactamase_156_184,TEM-1,beta-lactamase_156,P62593,1.00008,NO,184,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.593,-2.346,0.753,,,H,A,0.55,-0.87,1.671,,62.94,HHH,-1.41,0.111618,0.00356019,1.00008 beta-lactamase_156_T139S,beta-lactamase_156_139,TEM-1,beta-lactamase_156,P62593,1.00008,NO,139,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.901,-2.265,0.364,,0.216,H,A,0.22,0.39,16.34,16.34,77.62,PPH,-2.04667,0.111618,0.00441837,1.00008 kka2_1:1_K112K,kka2_1:1_112,Kka2,kka2_1:1,P00552,1.00008,NO,112,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-2.491,-2.491,,,0.076,H,A,2.34,-1.37,23.433,23.433,56.06,ABH,-2.00133,0.520039,0.00645389,1.00008 kka2_1:1_R121R,kka2_1:1_121,Kka2,kka2_1:1,P00552,1.00008,NO,121,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.552,-1.552,,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.520039,0.00523326,1.00008 kka2_1:8_G95G,kka2_1:8_95,Kka2,kka2_1:8,P00552,1.00008,NO,95,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-2.403,-2.403,,,0.126,E,B,0.75,-0.74,7.774,,71.59,HOA,-2.198,0.100394,0.00743616,1.00008 kka2_1:8_G95G,kka2_1:8_95,Kka2,kka2_1:8,P00552,1.00008,NO,95,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-2.403,-2.403,,,0.126,E,B,0.75,-0.74,7.774,,71.59,HOA,-2.198,0.100394,0.00743616,1.00008 kka2_1:8_P45P,kka2_1:8_45,Kka2,kka2_1:8,P00552,1.00008,NO,45,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.774,-1.774,,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.100394,0.00590481,1.00008 kka2_1:8_P45P,kka2_1:8_45,Kka2,kka2_1:8,P00552,1.00008,NO,45,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.774,-1.774,,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.100394,0.00590481,1.00008 beta-lactamase_156_A77T,beta-lactamase_156_77,TEM-1,beta-lactamase_156,P62593,1.00009,NO,77,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.234,-2.687,1.453,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.111618,0.00282362,1.00009 beta-lactamase_156_T263A,beta-lactamase_156_263,TEM-1,beta-lactamase_156,P62593,1.00009,NO,263,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.111618,0.0110582,1.00009 beta-lactamase_39_I54Y,beta-lactamase_39_54,TEM-1,beta-lactamase_39,P62593,1.00009,NO,54,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-2.838,-4.264,1.426,,0.669,E,B,0.48,-0.14,1.349,,73.78,BHH,-2.337,0.0495842,0.00403589,1.00009 beta-lactamase_39_P224L,beta-lactamase_39_224,TEM-1,beta-lactamase_39,P62593,1.00009,NO,224,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.893,-3.582,2.689,,0.383,,B,0.52,-0.3,3.169,,74.48,HOH,-1.26433,0.0495842,0.00189564,1.00009 beta-lactamase_625_H156N,beta-lactamase_625_156,TEM-1,beta-lactamase_625,P62593,1.00009,NO,156,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-3.156,-2.52,-0.636,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.213352,0.00468596,1.00009 beta-lactamase_L167L,beta-lactamase_167,TEM-1,beta-lactamase,P62593,1.00009,NO,167,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.138,-1.138,,5.13111,0.015,G,A,0.08,-0.63,0.4,,64.69,AHP,-1.30767,0.221079,0.00303566,1.00009 kka2_1:1_D101D,kka2_1:1_101,Kka2,kka2_1:1,P00552,1.00009,NO,101,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.028,-1.028,,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.520039,0.00423361,1.00009 kka2_1:1_H139H,kka2_1:1_139,Kka2,kka2_1:1,P00552,1.00009,NO,139,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-2.809,-2.809,,,0.471,H,A,0.17,0.68,1.153,,63.64,BBB,-2.22,0.520039,0.00734779,1.00009 kka2_1:1_M148M,kka2_1:1_148,Kka2,kka2_1:1,P00552,1.00009,NO,148,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.847,-1.847,,,0.268,H,A,1.59,0.71,4.618,,64.39,BHA,-1.65467,0.520039,0.00982664,1.00009 kka2_1:1_Y244Y,kka2_1:1_244,Kka2,kka2_1:1,P00552,1.00009,NO,244,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-0.775,-0.775,,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.520039,0.00453187,1.00009 kka2_1:4_F37F,kka2_1:4_37,Kka2,kka2_1:4,P00552,1.00009,NO,37,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.427,-1.427,,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.168804,0.00586193,1.00009 beta-lactamase_156_G141V,beta-lactamase_156_141,TEM-1,beta-lactamase_156,P62593,1.0001,NO,141,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-0.828,-3.79,2.962,,0.575,T,l,0.29,-0.28,0.198,,64.69,HOO,-1.08933,0.111618,0.0012419,1.0001 beta-lactamase_156_G154L,beta-lactamase_156_154,TEM-1,beta-lactamase_156,P62593,1.0001,NO,154,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.823,-3.779,2.956,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.111618,0.00180205,1.0001 beta-lactamase_39_E145T,beta-lactamase_39_145,TEM-1,beta-lactamase_39,P62593,1.0001,NO,145,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.357,-3.565,1.208,,0.545,H,A,1.04,0.79,1.199,,77.62,BAH,-2.069,0.0495842,0.00553285,1.0001 kka2_1:1_S104S,kka2_1:1_104,Kka2,kka2_1:1,P00552,1.0001,NO,104,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.436,-1.436,,,0.536,T,A,0.27,-1.11,5.49,,63.64,HPP,-1.91433,0.520039,0.00555207,1.0001 kka2_1:2_E63E,kka2_1:2_63,Kka2,kka2_1:2,P00552,1.0001,NO,63,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-0.762,-0.762,,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.295029,0.00118399,1.0001 kka2_1:2_G95G,kka2_1:2_95,Kka2,kka2_1:2,P00552,1.0001,NO,95,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-2.403,-2.403,,,0.126,E,B,0.29,-0.74,0.359,,71.59,HOA,-2.198,0.295029,0.00743616,1.0001 beta-lactamase_156_G194E,beta-lactamase_156_194,TEM-1,beta-lactamase_156,P62593,1.00011,NO,194,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.396,-2.361,0.965,,0.276,S,b,0.29,0.36,1.346,,67.83,POA,-1.832,0.111618,0.00392163,1.00011 beta-lactamase_156_R273H,beta-lactamase_156_273,TEM-1,beta-lactamase_156,P62593,1.00011,NO,273,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.314,-4.599,2.285,,0.564,H,A,1.2,1.57,20.248,20.248,73.78,ABP,-1.841,0.111618,0.0077952,1.00011 kka2_1:1_F37F,kka2_1:1_37,Kka2,kka2_1:1,P00552,1.00011,NO,37,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.427,-1.427,,,0.219,E,B,0.58,-0.25,18.64,18.64,64.39,HHB,-1.17733,0.520039,0.00586193,1.00011 kka2_1:1_G181G,kka2_1:1_181,Kka2,kka2_1:1,P00552,1.00011,NO,181,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-2.698,-2.698,,,0.379,S,B,0.75,0.78,15.356,15.356,71.59,AOA,-2.21,0.520039,0.00728319,1.00011 kka2_1:1_L39L,kka2_1:1_39,Kka2,kka2_1:1,P00552,1.00011,NO,39,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.223,-1.223,,,,E,B,0.55,-1.21,0.925,,71.59,BHP,-1.69167,0.520039,0.00493618,1.00011 kka2_1:1_W91W,kka2_1:1_91,Kka2,kka2_1:1,P00552,1.00011,NO,91,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-1.178,-1.178,,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.520039,0.00358653,1.00011 kka2_1:2_L67L,kka2_1:2_67,Kka2,kka2_1:2,P00552,1.00011,NO,67,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.741,-0.741,,,0.007,H,A,1.59,-0.66,,,,BHP,-1.42867,0.295029,0.00102787,1.00011 kka2_1:8_A64A,kka2_1:8_64,Kka2,kka2_1:8,P00552,1.00011,NO,64,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.496,-1.496,,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.100394,0.00705578,1.00011 kka2_1:8_A64A,kka2_1:8_64,Kka2,kka2_1:8,P00552,1.00011,NO,64,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.496,-1.496,,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.100394,0.00705578,1.00011 kka2_1:8_F37F,kka2_1:8_37,Kka2,kka2_1:8,P00552,1.00011,NO,37,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.427,-1.427,,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.100394,0.00586193,1.00011 kka2_1:8_F37F,kka2_1:8_37,Kka2,kka2_1:8,P00552,1.00011,NO,37,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.427,-1.427,,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.100394,0.00586193,1.00011 kka2_1:8_N200N,kka2_1:8_200,Kka2,kka2_1:8,P00552,1.00011,NO,200,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-2.446,-2.446,,,0.756,T,L,0.43,-0.08,2.528,,64.39,APO,-2.08,0.100394,0.00838549,1.00011 kka2_1:8_N200N,kka2_1:8_200,Kka2,kka2_1:8,P00552,1.00011,NO,200,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-2.446,-2.446,,,0.756,T,L,0.43,-0.08,2.528,,64.39,APO,-2.08,0.100394,0.00838549,1.00011 kka2_1:8_P98P,kka2_1:8_98,Kka2,kka2_1:8,P00552,1.00011,NO,98,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.526,-1.526,,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.100394,0.00622754,1.00011 kka2_1:8_P98P,kka2_1:8_98,Kka2,kka2_1:8,P00552,1.00011,NO,98,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.526,-1.526,,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.100394,0.00622754,1.00011 beta-lactamase_156_L199C,beta-lactamase_156_199,TEM-1,beta-lactamase_156,P62593,1.00012,NO,199,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-2.942,-5.078,2.136,,0.832,H,A,0.55,0.42,1.552,,77.62,PHH,-2.32933,0.111618,0.0048649,1.00012 beta-lactamase_39_L79T,beta-lactamase_39_79,TEM-1,beta-lactamase_39,P62593,1.00012,NO,79,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.842,-3.447,2.605,,0.007,H,A,0.55,-0.16,0.823,,50.35,HHP,-1.44333,0.0495842,0.000947397,1.00012 beta-lactamase_625_V157H,beta-lactamase_625_157,TEM-1,beta-lactamase_625,P62593,1.00012,NO,157,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.751,-3.319,1.568,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.213352,0.00506849,1.00012 beta-lactamase_K213L,beta-lactamase_213,TEM-1,beta-lactamase,P62593,1.00012,NO,213,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.81,-3.558,1.748,5.63167,0.67,,A,1.59,0.29,3.924,,67.83,ABH,-1.57767,0.221079,0.00610411,1.00012 kka2_1:1_G10G,kka2_1:1_10,Kka2,kka2_1:1,P00552,1.00012,NO,10,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.921,-1.921,,,,,,,,1.862,,71.59,HOP,-2.10733,0.520039,0.00289233,1.00012 kka2_1:2_D227D,kka2_1:2_227,Kka2,kka2_1:2,P00552,1.00012,NO,227,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.758,-1.758,,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.295029,0.00745029,1.00012 kka2_1:2_L93L,kka2_1:2_93,Kka2,kka2_1:2,P00552,1.00012,NO,93,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.815,-0.815,,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.295029,0.00131498,1.00012 beta-lactamase_0_R81D,beta-lactamase_0_81,TEM-1,beta-lactamase_0,P62593,1.00013,NO,81,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.466,-3.611,2.145,,0.218,H,A,1.2,1.66,0.332,,50,PBH,-1.60667,0.0500837,0.00499763,1.00013 beta-lactamase_156_E35G,beta-lactamase_156_35,TEM-1,beta-lactamase_156,P62593,1.00013,NO,35,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-0.869,-3.356,2.487,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.111618,0.00174441,1.00013 beta-lactamase_156_G216A,beta-lactamase_156_216,TEM-1,beta-lactamase_156,P62593,1.00013,NO,216,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.477,-2.596,1.119,,0.437,I,A,0.29,-0.58,12.464,12.464,74.48,HOO,-1.68067,0.111618,0.00639568,1.00013 beta-lactamase_156_R257Q,beta-lactamase_156_257,TEM-1,beta-lactamase_156,P62593,1.00013,NO,257,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.111618,0.00756629,1.00013 beta-lactamase_2500_T112V,beta-lactamase_2500_112,TEM-1,beta-lactamase_2500,P62593,1.00013,NO,112,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.186,-2.929,0.743,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.361275,0.00531334,1.00013 beta-lactamase_625_T269I,beta-lactamase_625_269,TEM-1,beta-lactamase_625,P62593,1.00013,NO,269,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.213352,0.00950944,1.00013 kka2_1:1_A71A,kka2_1:1_71,Kka2,kka2_1:1,P00552,1.00013,NO,71,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.824,-1.824,,,0.553,H,A,0.46,0.08,9.788,,64.39,HHP,-1.74033,0.520039,0.00727707,1.00013 beta-lactamase_2500_D36V,beta-lactamase_2500_36,TEM-1,beta-lactamase_2500,P62593,1.00014,NO,36,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.732,-3.726,0.994,,0.555,H,A,0.75,1.17,2.26,,77.62,AAP,-1.91167,0.361275,0.00476483,1.00014 beta-lactamase_39_E46S,beta-lactamase_39_46,TEM-1,beta-lactamase_39,P62593,1.00014,NO,46,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.94,-3.545,1.605,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.0495842,0.00427568,1.00014 beta-lactamase_39_I261L,beta-lactamase_39_261,TEM-1,beta-lactamase_39,P62593,1.00014,NO,261,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.0495842,0.0123091,1.00014 beta-lactamase_39_P255R,beta-lactamase_39_255,TEM-1,beta-lactamase_39,P62593,1.00014,NO,255,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-2.266,-4.188,1.922,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.0495842,0.00499612,1.00014 beta-lactamase_625_A77Y,beta-lactamase_625_77,TEM-1,beta-lactamase_625,P62593,1.00014,NO,77,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.234,-4.173,2.939,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.213352,0.00282362,1.00014 beta-lactamase_625_K32E,beta-lactamase_625_32,TEM-1,beta-lactamase_625,P62593,1.00014,NO,32,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.984,-2.418,0.434,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.213352,0.00401283,1.00014 beta-lactamase_625_R162Q,beta-lactamase_625_162,TEM-1,beta-lactamase_625,P62593,1.00014,NO,162,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.016,-3.59,2.574,,0.124,S,B,1.2,-0.37,1.445,,64.69,ABH,-1.25,0.213352,0.000561334,1.00014 kka2_1:1_E169E,kka2_1:1_169,Kka2,kka2_1:1,P00552,1.00014,NO,169,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.996,-1.996,,,0.422,H,A,1.04,0.3,7.546,7.546,65.53,HAH,-1.755,0.520039,0.00730086,1.00014 kka2_1:1_G21G,kka2_1:1_21,Kka2,kka2_1:1,P00552,1.00014,NO,21,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.368,-1.368,,,0.586,T,l,0.29,-0.75,10.291,10.291,71.59,HOH,-2.10167,0.520039,0.00709648,1.00014 kka2_1:2_F171F,kka2_1:2_171,Kka2,kka2_1:2,P00552,1.00014,NO,171,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.326,-1.326,,,0.154,H,A,0.58,-0.1,2.645,,63.64,HHH,-1.45433,0.295029,0.00821426,1.00014 beta-lactamase_156_G114N,beta-lactamase_156_114,TEM-1,beta-lactamase_156,P62593,1.00015,NO,114,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.094,-2.731,1.637,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.111618,0.00224919,1.00015 beta-lactamase_156_R239P,beta-lactamase_156_239,TEM-1,beta-lactamase_156,P62593,1.00015,NO,239,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.111618,0.00213852,1.00015 beta-lactamase_39_L74C,beta-lactamase_39_74,TEM-1,beta-lactamase_39,P62593,1.00015,NO,74,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.296,-4.647,3.351,,,H,A,0.55,-0.91,1.581,,50,HHO,-1.34933,0.0495842,0.00493255,1.00015 beta-lactamase_39_R189E,beta-lactamase_39_189,TEM-1,beta-lactamase_39,P62593,1.00015,NO,189,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.844,-2.256,0.412,,0.278,H,A,1.2,1.01,12.11,12.11,72.73,HBB,-1.668,0.0495842,0.0050699,1.00015 kka2_1:1_D154D,kka2_1:1_154,Kka2,kka2_1:1,P00552,1.00015,NO,154,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.876,-0.876,,,0.457,.,b,0.75,1.48,0.658,,52.65,HAP,-1.52467,0.520039,0.00292633,1.00015 kka2_1:1_E262E,kka2_1:1_262,Kka2,kka2_1:1,P00552,1.00015,NO,262,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-0.829,-0.829,,,0.059,G,A,1.04,-0.18,0.837,,42.42,AAH,-0.816,0.520039,0.0191586,1.00015 kka2_1:1_L102L,kka2_1:1_102,Kka2,kka2_1:1,P00552,1.00015,NO,102,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.804,-0.804,,,,T,A,0.55,-1.17,4.258,,42.42,AHH,-1.398,0.520039,0.00201332,1.00015 kka2_1:2_G164G,kka2_1:2_164,Kka2,kka2_1:2,P00552,1.00015,NO,164,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.869,-0.869,,,0.862,T,l,0.75,1.45,1.539,,64.39,POH,-1.828,0.295029,0.00442091,1.00015 kka2_1:2_S104S,kka2_1:2_104,Kka2,kka2_1:2,P00552,1.00015,NO,104,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.436,-1.436,,,0.536,T,A,0.27,-1.11,5.49,,63.64,HPP,-1.91433,0.295029,0.00555207,1.00015 kka2_1:4_W15W,kka2_1:4_15,Kka2,kka2_1:4,P00552,1.00015,NO,15,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-1.392,-1.392,,,0.01,G,A,0.47,0.15,0.943,,52.27,HHH,-2.10533,0.168804,0.00585505,1.00015 kka2_1:8_R145R,kka2_1:8_145,Kka2,kka2_1:8,P00552,1.00015,NO,145,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.804,-1.804,,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.100394,0.00846663,1.00015 kka2_1:8_R145R,kka2_1:8_145,Kka2,kka2_1:8,P00552,1.00015,NO,145,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.804,-1.804,,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.100394,0.00846663,1.00015 kka2_1:8_W15W,kka2_1:8_15,Kka2,kka2_1:8,P00552,1.00015,NO,15,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-1.392,-1.392,,,0.01,G,A,1.51,0.15,0.827,,52.27,HHH,-2.10533,0.100394,0.00585505,1.00015 kka2_1:8_W15W,kka2_1:8_15,Kka2,kka2_1:8,P00552,1.00015,NO,15,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-1.392,-1.392,,,0.01,G,A,1.51,0.15,0.827,,52.27,HHH,-2.10533,0.100394,0.00585505,1.00015 beta-lactamase_E169L,beta-lactamase_169,TEM-1,beta-lactamase,P62593,1.00016,NO,169,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.23,-3.533,2.303,5.78896,0.337,,A,0.52,1,1.806,,73.08,PAH,-1.16533,0.221079,0.00400994,1.00016 beta-lactamase_P249K,beta-lactamase_249,TEM-1,beta-lactamase,P62593,1.00016,NO,249,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.312,-3.564,2.252,5.10655,0.256,S,B,0.99,0.04,0.479,,72.73,OOA,-1.81367,0.221079,0.00220169,1.00016 kka2_1:1_A108A,kka2_1:1_108,Kka2,kka2_1:1,P00552,1.00016,NO,108,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.061,-2.061,,,0.243,.,B,0.46,-1.34,3.156,,71.59,HHO,-1.57033,0.520039,0.00751209,1.00016 kka2_1:1_F256F,kka2_1:1_256,Kka2,kka2_1:1,P00552,1.00016,NO,256,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.49,-1.49,,,,H,A,1.62,-0.78,2.354,,53.03,HHH,-1.423,0.520039,0.0132841,1.00016 kka2_1:1_I254I,kka2_1:1_254,Kka2,kka2_1:1,P00552,1.00016,NO,254,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.933,-1.933,,,0.135,H,A,1.52,-0.6,1.859,,71.59,BHH,-1.668,0.520039,0.0132375,1.00016 kka2_1:1_L126L,kka2_1:1_126,Kka2,kka2_1:1,P00552,1.00016,NO,126,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.246,-1.246,,,0.285,S,B,0.55,0.12,0.302,,51.89,PHA,-1.744,0.520039,0.0066485,1.00016 kka2_1:8_L57L,kka2_1:8_57,Kka2,kka2_1:8,P00552,1.00016,NO,57,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.898,-1.898,,,0.343,T,A,0.55,0.98,13.359,13.359,52.65,HHP,-2.20733,0.100394,0.00723769,1.00016 kka2_1:8_L57L,kka2_1:8_57,Kka2,kka2_1:8,P00552,1.00016,NO,57,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.898,-1.898,,,0.343,T,A,0.55,0.98,13.359,13.359,52.65,HHP,-2.20733,0.100394,0.00723769,1.00016 beta-lactamase_2500_K30A,beta-lactamase_2500_30,TEM-1,beta-lactamase_2500,P62593,1.00017,NO,30,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-2.307,-2.101,-0.206,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.361275,0.00448593,1.00017 beta-lactamase_39_I54T,beta-lactamase_39_54,TEM-1,beta-lactamase_39,P62593,1.00017,NO,54,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-2.838,-2.043,-0.795,,0.669,E,B,0.48,-0.14,1.349,,73.78,BHH,-2.337,0.0495842,0.00403589,1.00017 kka2_1:1_G30G,kka2_1:1_30,Kka2,kka2_1:1,P00552,1.00017,NO,30,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.596,-0.596,,,0.54,S,g,0.29,3.76,,,,HOO,-1.51133,0.520039,0.00159208,1.00017 kka2_1:1_L152L,kka2_1:1_152,Kka2,kka2_1:1,P00552,1.00017,NO,152,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.521,-1.521,,,0.547,.,A,0.55,1.36,1.589,,63.64,OHH,-1.162,0.520039,0.00674868,1.00017 kka2_1:1_L184L,kka2_1:1_184,Kka2,kka2_1:1,P00552,1.00017,NO,184,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.496,-1.496,,,0.489,E,B,0.55,-0.06,19.127,19.127,63.26,AHH,-1.24833,0.520039,0.00518742,1.00017 kka2_1:1_V49V,kka2_1:1_49,Kka2,kka2_1:1,P00552,1.00017,NO,49,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.614,-1.614,,,,E,B,0.44,-0.77,3.665,3.665,64.39,HHB,-1.3,0.520039,0.00615685,1.00017 kka2_1:4_G164G,kka2_1:4_164,Kka2,kka2_1:4,P00552,1.00017,NO,164,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.869,-0.869,,,0.862,T,l,0.75,1.45,1.539,,64.39,POH,-1.828,0.168804,0.00442091,1.00017 kka2_1:4_W24W,kka2_1:4_24,Kka2,kka2_1:4,P00552,1.00017,NO,24,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-1.779,-1.779,,,0.477,E,B,1.51,-0.21,2.666,,56.06,AHH,-2.24467,0.168804,0.00631564,1.00017 beta-lactamase_39_V259L,beta-lactamase_39_259,TEM-1,beta-lactamase_39,P62593,1.00018,NO,259,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.0495842,0.0070773,1.00018 kka2_1:1_A166A,kka2_1:1_166,Kka2,kka2_1:1,P00552,1.00018,NO,166,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.407,-2.407,,,0.534,.,B,0.46,1.03,1.147,,71.59,HHO,-2.421,0.520039,0.00799912,1.00018 kka2_1:1_E235E,kka2_1:1_235,Kka2,kka2_1:1,P00552,1.00018,NO,235,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.955,-1.955,,,0.631,H,A,1.52,0.12,8.521,,65.53,OAH,-2.07267,0.520039,0.0102806,1.00018 kka2_1:1_F133F,kka2_1:1_133,Kka2,kka2_1:1,P00552,1.00018,NO,133,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-0.871,-0.871,,,0.178,.,B,0.58,0.43,1.999,,42.42,OHA,-0.871667,0.520039,0.00182168,1.00018 kka2_1:1_L123L,kka2_1:1_123,Kka2,kka2_1:1,P00552,1.00018,NO,123,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.888,-0.888,,,0.007,H,A,0.55,-0.4,1.447,,48.86,BHB,-1.301,0.520039,0.00325188,1.00018 kka2_1:1_L170L,kka2_1:1_170,Kka2,kka2_1:1,P00552,1.00018,NO,170,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.28,-1.28,,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.520039,0.00730791,1.00018 kka2_1:1_R202R,kka2_1:1_202,Kka2,kka2_1:1,P00552,1.00018,NO,202,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.761,-1.761,,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.520039,0.00696498,1.00018 kka2_1:4_M148M,kka2_1:4_148,Kka2,kka2_1:4,P00552,1.00018,NO,148,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.847,-1.847,,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.168804,0.00982664,1.00018 kka2_1:8_D127D,kka2_1:8_127,Kka2,kka2_1:8,P00552,1.00018,NO,127,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.364,-1.364,,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.100394,0.00660501,1.00018 kka2_1:8_D127D,kka2_1:8_127,Kka2,kka2_1:8,P00552,1.00018,NO,127,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.364,-1.364,,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.100394,0.00660501,1.00018 beta-lactamase_156_H156C,beta-lactamase_156_156,TEM-1,beta-lactamase_156,P62593,1.00019,NO,156,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-3.156,-5.208,2.052,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.111618,0.00468596,1.00019 beta-lactamase_156_Q204M,beta-lactamase_156_204,TEM-1,beta-lactamase_156,P62593,1.00019,NO,204,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-1.382,-4.445,3.063,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.111618,0.00364106,1.00019 kka2_1:1_E111E,kka2_1:1_111,Kka2,kka2_1:1,P00552,1.00019,NO,111,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.28,-2.28,,,0.155,H,A,1.52,-1.14,15.716,15.716,65.53,HAB,-2.27833,0.520039,0.00746789,1.00019 kka2_1:2_E59E,kka2_1:2_59,Kka2,kka2_1:2,P00552,1.00019,NO,59,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-0.952,-0.952,,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.295029,0.00280355,1.00019 beta-lactamase_0_V78S,beta-lactamase_0_78,TEM-1,beta-lactamase_0,P62593,1.0002,NO,78,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.459,-3.701,2.242,,,H,A,0.44,-0.47,16.615,16.615,63.64,HHH,-1.17833,0.0500837,0.00492501,1.0002 kka2_1:1_E142E,kka2_1:1_142,Kka2,kka2_1:1,P00552,1.0002,NO,142,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.221,-2.221,,,0.471,H,A,1.52,0.85,3.626,,65.53,HAB,-2.08033,0.520039,0.00748883,1.0002 kka2_1:1_E182E,kka2_1:1_182,Kka2,kka2_1:1,P00552,1.0002,NO,182,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.516,-1.516,,,0.326,,B,1.52,0.75,14.547,14.547,65.53,OAA,-1.806,0.520039,0.00641548,1.0002 kka2_1:1_F264F,kka2_1:1_264,Kka2,kka2_1:1,P00552,1.0002,NO,264,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.02,-1.02,,,0.296,.,?,0.58,0.02,2.303,,71.59,HHNA,-0.9655,0.520039,,1.0002 kka2_1:2_D127D,kka2_1:2_127,Kka2,kka2_1:2,P00552,1.0002,NO,127,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.364,-1.364,,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.295029,0.00660501,1.0002 kka2_1:4_N200N,kka2_1:4_200,Kka2,kka2_1:4,P00552,1.0002,NO,200,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-2.446,-2.446,,,0.756,T,L,0.61,-0.08,1.746,,64.39,APO,-2.08,0.168804,0.00838549,1.0002 kka2_1:8_D157D,kka2_1:8_157,Kka2,kka2_1:8,P00552,1.0002,NO,157,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.993,-0.993,,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.100394,0.0042313,1.0002 kka2_1:8_D157D,kka2_1:8_157,Kka2,kka2_1:8,P00552,1.0002,NO,157,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.993,-0.993,,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.100394,0.0042313,1.0002 beta-lactamase_0_S96T,beta-lactamase_0_96,TEM-1,beta-lactamase_0,P62593,1.00021,NO,96,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.27,-2.436,0.166,,0.368,,b,0.27,0.39,2.516,,73.78,HPP,-2.019,0.0500837,0.00551835,1.00021 beta-lactamase_625_T193Q,beta-lactamase_625_193,TEM-1,beta-lactamase_625,P62593,1.00021,NO,193,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.914,-4.169,2.255,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.213352,0.00482669,1.00021 kka2_1:1_D159D,kka2_1:1_159,Kka2,kka2_1:1,P00552,1.00021,NO,159,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.82,-0.82,,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.520039,0.0030485,1.00021 kka2_1:1_R239R,kka2_1:1_239,Kka2,kka2_1:1,P00552,1.00021,NO,239,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.949,-2.949,,,0.15,H,A,1.2,-0.31,0.477,,71.59,ABH,-2.23,0.520039,0.00835326,1.00021 kka2_1:1_S105S,kka2_1:1_105,Kka2,kka2_1:1,P00552,1.00021,NO,105,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.945,-1.945,,,0.056,S,B,0.27,-1.04,3.442,,65.53,PPB,-2.17033,0.520039,0.00847233,1.00021 kka2_1:2_D118D,kka2_1:2_118,Kka2,kka2_1:2,P00552,1.00021,NO,118,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.07,-2.07,,,0.61,H,A,0.75,-0.05,2.237,,64.39,HAH,-1.32367,0.295029,0.0067852,1.00021 kka2_1:2_R121R,kka2_1:2_121,Kka2,kka2_1:2,P00552,1.00021,NO,121,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.552,-1.552,,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.295029,0.00523326,1.00021 kka2_1:2_W91W,kka2_1:2_91,Kka2,kka2_1:2,P00552,1.00021,NO,91,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-1.178,-1.178,,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.295029,0.00358653,1.00021 kka2_1:4_P128P,kka2_1:4_128,Kka2,kka2_1:4,P00552,1.00021,NO,128,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.922,-1.922,,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.168804,0.00774689,1.00021 kka2_1:4_R253R,kka2_1:4_253,Kka2,kka2_1:4,P00552,1.00021,NO,253,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.356,-1.356,,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.168804,0.0144195,1.00021 kka2_1:8_I141I,kka2_1:8_141,Kka2,kka2_1:8,P00552,1.00021,NO,141,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.495,-1.495,,,0.068,H,A,1.52,-0.01,2.144,,92.05,BHA,-1.689,0.100394,0.00744745,1.00021 kka2_1:8_I141I,kka2_1:8_141,Kka2,kka2_1:8,P00552,1.00021,NO,141,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.495,-1.495,,,0.068,H,A,1.52,-0.01,2.144,,92.05,BHA,-1.689,0.100394,0.00744745,1.00021 kka2_1:8_P128P,kka2_1:8_128,Kka2,kka2_1:8,P00552,1.00021,NO,128,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.922,-1.922,,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.100394,0.00774689,1.00021 kka2_1:8_P128P,kka2_1:8_128,Kka2,kka2_1:8,P00552,1.00021,NO,128,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.922,-1.922,,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.100394,0.00774689,1.00021 beta-lactamase_39_L137Q,beta-lactamase_39_137,TEM-1,beta-lactamase_39,P62593,1.00022,NO,137,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.03,-4.147,3.117,,,H,A,0.55,-0.38,0.674,,42.31,HHP,-1.58933,0.0495842,0.00278599,1.00022 beta-lactamase_V42I,beta-lactamase_42,TEM-1,beta-lactamase,P62593,1.00022,NO,42,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.564,-2.098,0.534,5.27904,0.017,E,B,1.64,-0.51,2.024,,63.99,BHO,-1.042,0.221079,0.00404515,1.00022 kka2_1:1_R38R,kka2_1:1_38,Kka2,kka2_1:1,P00552,1.00022,NO,38,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.207,-1.207,,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.520039,0.00372499,1.00022 kka2_1:2_A34A,kka2_1:2_34,Kka2,kka2_1:2,P00552,1.00022,NO,34,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.928,-0.928,,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.295029,0.00343484,1.00022 kka2_1:2_D250D,kka2_1:2_250,Kka2,kka2_1:2,P00552,1.00022,NO,250,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.015,-1.015,,,0.274,.,b,0.75,-0.46,3.796,,51.89,OAP,-1.83933,0.295029,0.0177103,1.00022 kka2_1:2_L39L,kka2_1:2_39,Kka2,kka2_1:2,P00552,1.00022,NO,39,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.223,-1.223,,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.295029,0.00493618,1.00022 kka2_1:2_M148M,kka2_1:2_148,Kka2,kka2_1:2,P00552,1.00022,NO,148,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.847,-1.847,,,0.268,H,A,1.59,0.71,1.439,,64.39,BHA,-1.65467,0.295029,0.00982664,1.00022 kka2_1:4_L19L,kka2_1:4_19,Kka2,kka2_1:4,P00552,1.00022,NO,19,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.254,-1.254,,,0.08,T,A,1.59,-0.26,2.645,,65.53,BHH,-2.221,0.168804,0.00620703,1.00022 kka2_1:4_L67L,kka2_1:4_67,Kka2,kka2_1:4,P00552,1.00022,NO,67,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.741,-0.741,,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.168804,0.00102787,1.00022 kka2_1:4_R147R,kka2_1:4_147,Kka2,kka2_1:4,P00552,1.00022,NO,147,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.123,-1.123,,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.168804,0.00549168,1.00022 kka2_1:8_G201N,kka2_1:8_201,Kka2,kka2_1:8,P00552,1.00022,NO,201,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.56,-2.642,1.082,,0.149,T,l,0.75,-0.57,2.152,,52.65,POB,-1.92233,0.100394,0.00820117,1.00022 kka2_1:8_G201N,kka2_1:8_201,Kka2,kka2_1:8,P00552,1.00022,NO,201,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.56,-2.642,1.082,,0.149,T,l,0.75,-0.57,2.152,,52.65,POB,-1.92233,0.100394,0.00820117,1.00022 beta-lactamase_156_S266G,beta-lactamase_156_266,TEM-1,beta-lactamase_156,P62593,1.00023,NO,266,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.111618,0.0140785,1.00023 beta-lactamase_2500_T193I,beta-lactamase_2500_193,TEM-1,beta-lactamase_2500,P62593,1.00023,NO,193,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.914,-2.798,0.884,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.361275,0.00482669,1.00023 beta-lactamase_625_E169F,beta-lactamase_625_169,TEM-1,beta-lactamase_625,P62593,1.00023,NO,169,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.23,-4.322,3.092,,0.337,,A,1.04,1,1.806,,73.08,PAH,-1.16533,0.213352,0.00400994,1.00023 kka2_1:1_C131C,kka2_1:1_131,Kka2,kka2_1:1,P00552,1.00023,NO,131,C,C,CC,Special,Special,5.07,5.07,0,0,121,121,0,108.5,108.5,0,-0.831,-0.831,,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.520039,0.00170814,1.00023 kka2_1:1_G88G,kka2_1:1_88,Kka2,kka2_1:1,P00552,1.00023,NO,88,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.689,-1.689,,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.520039,0.00685559,1.00023 kka2_1:1_R145R,kka2_1:1_145,Kka2,kka2_1:1,P00552,1.00023,NO,145,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.804,-1.804,,,0.346,H,A,1.2,1.23,23.699,23.699,63.64,HBP,-1.88033,0.520039,0.00846663,1.00023 kka2_1:2_I221I,kka2_1:2_221,Kka2,kka2_1:2,P00552,1.00023,NO,221,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.739,-1.739,,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.295029,0.00945908,1.00023 kka2_1:2_L70L,kka2_1:2_70,Kka2,kka2_1:2,P00552,1.00023,NO,70,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.017,-1.017,,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.295029,0.00411884,1.00023 kka2_1:2_V49V,kka2_1:2_49,Kka2,kka2_1:2,P00552,1.00023,NO,49,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.614,-1.614,,,,E,B,0.44,-0.77,1.233,,64.39,HHB,-1.3,0.295029,0.00615685,1.00023 kka2_1:8_R253R,kka2_1:8_253,Kka2,kka2_1:8,P00552,1.00023,NO,253,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.356,-1.356,,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.100394,0.0144195,1.00023 kka2_1:8_R253R,kka2_1:8_253,Kka2,kka2_1:8,P00552,1.00023,NO,253,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.356,-1.356,,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.100394,0.0144195,1.00023 kka2_1:8_S204S,kka2_1:8_204,Kka2,kka2_1:8,P00552,1.00023,NO,204,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.353,-1.353,,,0.144,E,A,0.27,-1.2,0.368,,65.53,HPO,-0.953333,0.100394,0.00881794,1.00023 kka2_1:8_S204S,kka2_1:8_204,Kka2,kka2_1:8,P00552,1.00023,NO,204,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.353,-1.353,,,0.144,E,A,0.27,-1.2,0.368,,65.53,HPO,-0.953333,0.100394,0.00881794,1.00023 kka2_1:8_V153V,kka2_1:8_153,Kka2,kka2_1:8,P00552,1.00023,NO,153,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.092,-1.092,,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.100394,0.00501119,1.00023 kka2_1:8_V153V,kka2_1:8_153,Kka2,kka2_1:8,P00552,1.00023,NO,153,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.092,-1.092,,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.100394,0.00501119,1.00023 beta-lactamase_156_N130S,beta-lactamase_156_130,TEM-1,beta-lactamase_156,P62593,1.00024,NO,130,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-0.798,-2.936,2.138,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.111618,0.000683376,1.00024 beta-lactamase_156_R202C,beta-lactamase_156_202,TEM-1,beta-lactamase_156,P62593,1.00024,NO,202,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.292,-5.047,3.755,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.111618,0.00321899,1.00024 kka2_1:1_A110A,kka2_1:1_110,Kka2,kka2_1:1,P00552,1.00024,NO,110,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.064,-2.064,,,0.175,H,A,1.04,-1.19,11.755,,71.59,OHA,-1.91867,0.520039,0.00759851,1.00024 kka2_1:1_A129A,kka2_1:1_129,Kka2,kka2_1:1,P00552,1.00024,NO,129,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.656,-1.656,,,0.845,G,A,0.46,0.72,19.686,19.686,92.05,OHP,-1.99,0.520039,0.00726862,1.00024 kka2_1:1_F240F,kka2_1:1_240,Kka2,kka2_1:1,P00552,1.00024,NO,240,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-0.911,-0.911,,,,H,A,1.62,-1.21,5.798,,50.38,BHH,-1.67267,0.520039,0.00552543,1.00024 kka2_1:1_G245G,kka2_1:1_245,Kka2,kka2_1:1,P00552,1.00024,NO,245,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.812,-0.812,,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.520039,0.00683899,1.00024 kka2_1:1_R44R,kka2_1:1_44,Kka2,kka2_1:1,P00552,1.00024,NO,44,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.062,-2.062,,,0.487,S,B,1.2,-0.35,2.717,,71.59,OBO,-1.80767,0.520039,0.00745043,1.00024 kka2_1:2_D62D,kka2_1:2_62,Kka2,kka2_1:2,P00552,1.00024,NO,62,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.591,-1.591,,,0.262,H,A,0.75,0.08,10.048,10.048,64.39,PAA,-1.77833,0.295029,0.00744243,1.00024 kka2_1:2_H124H,kka2_1:2_124,Kka2,kka2_1:2,P00552,1.00024,NO,124,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-0.84,-0.84,,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.295029,0.00211296,1.00024 kka2_1:2_Y22Y,kka2_1:2_22,Kka2,kka2_1:2,P00552,1.00024,NO,22,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-1.583,-1.583,,,0.122,.,B,0.21,-0.8,1.838,,65.53,OHA,-1.80333,0.295029,0.00598977,1.00024 beta-lactamase_156_A222R,beta-lactamase_156_222,TEM-1,beta-lactamase_156,P62593,1.00025,NO,222,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.103,-4.005,1.902,,0.233,H,A,0.46,-0.25,2.461,,77.62,PHH,-1.63733,0.111618,0.00466094,1.00025 beta-lactamase_156_H94D,beta-lactamase_156_94,TEM-1,beta-lactamase_156,P62593,1.00025,NO,94,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-2.5,-3,0.5,,0.776,,B,0.17,1.24,11.583,11.583,77.62,HBH,-1.872,0.111618,0.00389226,1.00025 beta-lactamase_156_L28R,beta-lactamase_156_28,TEM-1,beta-lactamase_156,P62593,1.00025,NO,28,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.579,-2.903,1.324,,0.277,H,A,0.55,-0.16,3.262,,93.01,PHH,-2.11333,0.111618,0.00359321,1.00025 beta-lactamase_2500_K53N,beta-lactamase_2500_53,TEM-1,beta-lactamase_2500,P62593,1.00025,NO,53,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-2.313,-3.809,1.496,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.361275,0.00383383,1.00025 kka2_1:1_L107L,kka2_1:1_107,Kka2,kka2_1:1,P00552,1.00025,NO,107,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.238,-1.238,,,0.197,.,B,0.55,-1.1,3.542,,71.59,BHH,-2.143,0.520039,0.00561937,1.00025 kka2_1:1_W24W,kka2_1:1_24,Kka2,kka2_1:1,P00552,1.00025,NO,24,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-1.779,-1.779,,,0.477,E,B,0.47,-0.21,2.375,,56.06,AHH,-2.24467,0.520039,0.00631564,1.00025 kka2_1:2_D90D,kka2_1:2_90,Kka2,kka2_1:2,P00552,1.00025,NO,90,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.459,-2.459,,,0.104,E,B,0.75,0.73,6.085,,64.39,BAH,-1.72833,0.295029,0.00583842,1.00025 kka2_1:2_L126L,kka2_1:2_126,Kka2,kka2_1:2,P00552,1.00025,NO,126,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.246,-1.246,,,0.285,S,B,0.55,0.12,1.392,,51.89,PHA,-1.744,0.295029,0.0066485,1.00025 kka2_1:8_L60L,kka2_1:8_60,Kka2,kka2_1:8,P00552,1.00025,NO,60,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.997,-0.997,,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.100394,0.00262176,1.00025 kka2_1:8_L60L,kka2_1:8_60,Kka2,kka2_1:8,P00552,1.00025,NO,60,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.997,-0.997,,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.100394,0.00262176,1.00025 kka2_1:8_M1M,kka2_1:8_1,Kka2,kka2_1:8,P00552,1.00025,NO,1,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.787,-1.787,,,,,,,,16.725,16.725,62.12,NAHH,-1.787,0.100394,0.00251939,1.00025 kka2_1:8_M1M,kka2_1:8_1,Kka2,kka2_1:8,P00552,1.00025,NO,1,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.787,-1.787,,,,,,,,16.725,16.725,62.12,NAHH,-1.787,0.100394,0.00251939,1.00025 kka2_1:8_S105S,kka2_1:8_105,Kka2,kka2_1:8,P00552,1.00025,NO,105,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.945,-1.945,,,0.056,S,B,0.27,-1.04,2.115,,65.53,PPB,-2.17033,0.100394,0.00847233,1.00025 kka2_1:8_S105S,kka2_1:8_105,Kka2,kka2_1:8,P00552,1.00025,NO,105,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.945,-1.945,,,0.056,S,B,0.27,-1.04,2.115,,65.53,PPB,-2.17033,0.100394,0.00847233,1.00025 kka2_1:8_T51T,kka2_1:8_51,Kka2,kka2_1:8,P00552,1.00025,NO,51,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.199,-2.199,,,0.05,E,B,0.82,-0.05,5.399,,63.64,BPA,-1.76767,0.100394,0.00628861,1.00025 kka2_1:8_T51T,kka2_1:8_51,Kka2,kka2_1:8,P00552,1.00025,NO,51,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.199,-2.199,,,0.05,E,B,0.82,-0.05,5.399,,63.64,BPA,-1.76767,0.100394,0.00628861,1.00025 beta-lactamase_625_G265C,beta-lactamase_625_265,TEM-1,beta-lactamase_625,P62593,1.00026,NO,265,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.213352,0.00811926,1.00026 beta-lactamase_625_M270W,beta-lactamase_625_270,TEM-1,beta-lactamase_625,P62593,1.00026,NO,270,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.213352,0.00767762,1.00026 beta-lactamase_625_N173Q,beta-lactamase_625_173,TEM-1,beta-lactamase_625,P62593,1.00026,NO,173,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-2.663,-4.003,1.34,,1.044,T,l,0.61,1.25,1.426,,77.62,OPA,-1.46633,0.213352,0.0033769,1.00026 kka2_1:1_C209C,kka2_1:1_209,Kka2,kka2_1:1,P00552,1.00026,NO,209,C,C,CC,Special,Special,5.07,5.07,0,0,121,121,0,108.5,108.5,0,-0.906,-0.906,,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.520039,0.00260862,1.00026 kka2_1:1_D156D,kka2_1:1_156,Kka2,kka2_1:1,P00552,1.00026,NO,156,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.696,-1.696,,,0.884,T,A,0.75,1.87,1.044,,65.53,PAA,-1.765,0.520039,0.00926998,1.00026 kka2_1:1_K138K,kka2_1:1_138,Kka2,kka2_1:1,P00552,1.00026,NO,138,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-2.5,-2.5,,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.520039,0.00628542,1.00026 kka2_1:1_P12P,kka2_1:1_12,Kka2,kka2_1:1,P00552,1.00026,NO,12,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.853,-0.853,,,,.,B,0.52,1.25,0.261,,48.11,POH,-1.80767,0.520039,0.00500011,1.00026 kka2_1:1_T225T,kka2_1:1_225,Kka2,kka2_1:1,P00552,1.00026,NO,225,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.393,-2.393,,,0.036,H,A,0.22,-1.22,4.554,,63.64,HPB,-1.58733,0.520039,0.0113598,1.00026 kka2_1:8_G164G,kka2_1:8_164,Kka2,kka2_1:8,P00552,1.00026,NO,164,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.869,-0.869,,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.100394,0.00442091,1.00026 kka2_1:8_G164G,kka2_1:8_164,Kka2,kka2_1:8,P00552,1.00026,NO,164,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.869,-0.869,,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.100394,0.00442091,1.00026 kka2_1:8_N58N,kka2_1:8_58,Kka2,kka2_1:8,P00552,1.00026,NO,58,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-2.641,-2.641,,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.100394,0.00793425,1.00026 kka2_1:8_N58N,kka2_1:8_58,Kka2,kka2_1:8,P00552,1.00026,NO,58,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-2.641,-2.641,,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.100394,0.00793425,1.00026 beta-lactamase_156_A282F,beta-lactamase_156_282,TEM-1,beta-lactamase_156,P62593,1.00027,NO,282,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.111618,0.0449821,1.00027 beta-lactamase_2500_H156N,beta-lactamase_2500_156,TEM-1,beta-lactamase_2500,P62593,1.00027,NO,156,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-3.156,-2.52,-0.636,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.361275,0.00468596,1.00027 beta-lactamase_39_A246G,beta-lactamase_39_246,TEM-1,beta-lactamase_39,P62593,1.00027,NO,246,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.121,-3.675,1.554,,0.01,E,B,0.46,-1.01,1.331,,73.78,HHH,-1.55633,0.0495842,0.00569458,1.00027 beta-lactamase_39_E35H,beta-lactamase_39_35,TEM-1,beta-lactamase_39,P62593,1.00027,NO,35,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-0.869,-4.279,3.41,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.0495842,0.00174441,1.00027 kka2_1:1_I207I,kka2_1:1_207,Kka2,kka2_1:1,P00552,1.00027,NO,207,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.175,-1.175,,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.520039,0.00611824,1.00027 kka2_1:1_L103L,kka2_1:1_103,Kka2,kka2_1:1,P00552,1.00027,NO,103,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-2.362,-2.362,,,0.394,T,A,0.55,-0.99,4.121,,63.64,HHP,-1.534,0.520039,0.00574792,1.00027 kka2_1:2_F48F,kka2_1:2_48,Kka2,kka2_1:2,P00552,1.00027,NO,48,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.453,-1.453,,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.295029,0.00475422,1.00027 kka2_1:4_D127D,kka2_1:4_127,Kka2,kka2_1:4,P00552,1.00027,NO,127,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.364,-1.364,,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.168804,0.00660501,1.00027 beta-lactamase_39_H110C,beta-lactamase_39_110,TEM-1,beta-lactamase_39,P62593,1.00028,NO,110,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-1.706,-5.217,3.511,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.0495842,0.00441499,1.00028 beta-lactamase_K252A,beta-lactamase_252,TEM-1,beta-lactamase,P62593,1.00028,NO,252,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.94,-3.237,1.297,5.56823,0.766,,B,1.82,1.16,21.796,21.796,67.83,OBO,-2.03333,0.221079,0.00575769,1.00028 beta-lactamase_M127W,beta-lactamase_127,TEM-1,beta-lactamase,P62593,1.00028,NO,127,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-2.251,-3.502,1.251,5.40552,0.312,S,A,1.07,0.32,1.671,,72.73,PHP,-1.40433,0.221079,0.00437927,1.00028 kka2_1:1_D227D,kka2_1:1_227,Kka2,kka2_1:1,P00552,1.00028,NO,227,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.758,-1.758,,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.520039,0.00745029,1.00028 kka2_1:1_F206F,kka2_1:1_206,Kka2,kka2_1:1,P00552,1.00028,NO,206,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.349,-1.349,,,0.006,E,B,0.58,-1.21,0.978,,63.64,OHH,-1.04,0.520039,0.00936868,1.00028 kka2_1:1_L212L,kka2_1:1_212,Kka2,kka2_1:1,P00552,1.00028,NO,212,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.904,-0.904,,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.520039,0.0031426,1.00028 kka2_1:2_C192C,kka2_1:2_192,Kka2,kka2_1:2,P00552,1.00028,NO,192,C,C,CC,Special,Special,5.07,5.07,0,0,121,121,0,108.5,108.5,0,-1.067,-1.067,,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.295029,0.00485428,1.00028 kka2_1:2_C209C,kka2_1:2_209,Kka2,kka2_1:2,P00552,1.00028,NO,209,C,C,CC,Special,Special,5.07,5.07,0,0,121,121,0,108.5,108.5,0,-0.906,-0.906,,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.295029,0.00260862,1.00028 kka2_1:2_W24W,kka2_1:2_24,Kka2,kka2_1:2,P00552,1.00028,NO,24,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-1.779,-1.779,,,0.477,E,B,1.51,-0.21,2.666,,56.06,AHH,-2.24467,0.295029,0.00631564,1.00028 kka2_1:4_D90D,kka2_1:4_90,Kka2,kka2_1:4,P00552,1.00028,NO,90,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.459,-2.459,,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.168804,0.00583842,1.00028 kka2_1:4_E182E,kka2_1:4_182,Kka2,kka2_1:4,P00552,1.00028,NO,182,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.516,-1.516,,,0.326,.,B,1.04,0.75,4.755,,65.53,OAA,-1.806,0.168804,0.00641548,1.00028 kka2_1:4_S105S,kka2_1:4_105,Kka2,kka2_1:4,P00552,1.00028,NO,105,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.945,-1.945,,,0.056,S,B,0.77,-1.04,3.442,,65.53,PPB,-2.17033,0.168804,0.00847233,1.00028 beta-lactamase_156_I206E,beta-lactamase_156_206,TEM-1,beta-lactamase_156,P62593,1.00029,NO,206,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-2.429,-2.747,0.318,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.111618,0.00528934,1.00029 beta-lactamase_156_L223A,beta-lactamase_156_223,TEM-1,beta-lactamase_156,P62593,1.00029,NO,223,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.055,-3.102,2.047,,0.27,,B,0.55,0.09,1.511,,74.48,HHO,-1.35033,0.111618,0.00372793,1.00029 beta-lactamase_156_P165W,beta-lactamase_156_165,TEM-1,beta-lactamase_156,P62593,1.00029,NO,165,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.373,-5.352,3.979,,0.203,T,A,0.52,-0.31,3.907,,73.78,AOA,-1.359,0.111618,0.00549538,1.00029 beta-lactamase_39_E238I,beta-lactamase_39_238,TEM-1,beta-lactamase_39,P62593,1.00029,NO,238,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.0495842,0.00743256,1.00029 kka2_1:1_V36V,kka2_1:1_36,Kka2,kka2_1:1,P00552,1.00029,NO,36,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-0.898,-0.898,,,0.292,E,B,0.44,0.21,0.278,,52.27,HHH,-1.484,0.520039,0.00245633,1.00029 kka2_1:2_D82D,kka2_1:2_82,Kka2,kka2_1:2,P00552,1.00029,NO,82,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.946,-1.946,,,0.341,E,b,0.75,0.52,11.923,11.923,63.64,HAH,-1.98,0.295029,0.00637516,1.00029 kka2_1:2_W69W,kka2_1:2_69,Kka2,kka2_1:2,P00552,1.00029,NO,69,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-0.859,-0.859,,,0.164,H,A,0.47,0.15,5.074,,38.64,PHH,-1.49967,0.295029,0.0012874,1.00029 kka2_1:4_D62D,kka2_1:4_62,Kka2,kka2_1:4,P00552,1.00029,NO,62,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.591,-1.591,,,0.262,H,A,0.29,0.08,14.756,14.756,64.39,PAA,-1.77833,0.168804,0.00744243,1.00029 beta-lactamase_156_E169H,beta-lactamase_156_169,TEM-1,beta-lactamase_156,P62593,1.0003,NO,169,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.23,-4.45,3.22,,0.337,,A,1.04,1,3.516,,73.08,PAH,-1.16533,0.111618,0.00400994,1.0003 beta-lactamase_39_M66H,beta-lactamase_39_66,TEM-1,beta-lactamase_39,P62593,1.0003,NO,66,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.362,-4.866,3.504,,0.013,,A,0.55,-0.7,1.319,,73.08,OHH,-1.49567,0.0495842,0.00412876,1.0003 beta-lactamase_D250G,beta-lactamase_250,TEM-1,beta-lactamase,P62593,1.0003,NO,250,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.335,-2.781,0.446,5.72026,0.89,T,L,0.23,1.53,24.737,24.737,66.08,OAO,-1.85133,0.221079,0.00550899,1.0003 kka2_1:1_F263F,kka2_1:1_263,Kka2,kka2_1:1,P00552,1.0003,NO,263,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-0.911,-0.911,,,0.006,G,A,0.58,-0.12,2.284,,45.83,AHH,-0.92,0.520039,0.0172454,1.0003 kka2_1:1_Y257Y,kka2_1:1_257,Kka2,kka2_1:1,P00552,1.0003,NO,257,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-1.064,-1.064,,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.520039,0.0148191,1.0003 kka2_1:4_R89R,kka2_1:4_89,Kka2,kka2_1:4,P00552,1.0003,NO,89,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.548,-1.548,,,0.209,E,B,1.2,1.41,4.412,,64.39,OBA,-1.89867,0.168804,0.00524373,1.0003 kka2_1:8_L67L,kka2_1:8_67,Kka2,kka2_1:8,P00552,1.0003,NO,67,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.741,-0.741,,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.100394,0.00102787,1.0003 kka2_1:8_L67L,kka2_1:8_67,Kka2,kka2_1:8,P00552,1.0003,NO,67,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.741,-0.741,,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.100394,0.00102787,1.0003 beta-lactamase_625_V157K,beta-lactamase_625_157,TEM-1,beta-lactamase_625,P62593,1.00031,NO,157,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.751,-2.698,0.947,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.213352,0.00506849,1.00031 kka2_1:1_D261D,kka2_1:1_261,Kka2,kka2_1:1,P00552,1.00031,NO,261,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.708,-0.708,,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.520039,0.0224846,1.00031 kka2_1:1_I228I,kka2_1:1_228,Kka2,kka2_1:1,P00552,1.00031,NO,228,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.142,-1.142,,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.520039,0.00458834,1.00031 kka2_1:1_P109P,kka2_1:1_109,Kka2,kka2_1:1,P00552,1.00031,NO,109,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.412,-1.412,,,0.376,H,A,0.52,-1.25,18.506,18.506,65.53,HOH,-1.84567,0.520039,0.0070929,1.00031 kka2_1:2_G88G,kka2_1:2_88,Kka2,kka2_1:2,P00552,1.00031,NO,88,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.689,-1.689,,,0.54,S,l,0.75,1.51,2.814,,65.53,HOB,-1.718,0.295029,0.00685559,1.00031 kka2_1:2_S105S,kka2_1:2_105,Kka2,kka2_1:2,P00552,1.00031,NO,105,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.945,-1.945,,,0.056,S,B,0.27,-1.04,3.442,,65.53,PPB,-2.17033,0.295029,0.00847233,1.00031 kka2_1:2_S32S,kka2_1:2_32,Kka2,kka2_1:2,P00552,1.00031,NO,32,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-0.804,-0.804,,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.295029,0.00149998,1.00031 kka2_1:2_Y244Y,kka2_1:2_244,Kka2,kka2_1:2,P00552,1.00031,NO,244,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-0.775,-0.775,,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.295029,0.00453187,1.00031 kka2_1:8_S104S,kka2_1:8_104,Kka2,kka2_1:8,P00552,1.00031,NO,104,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.436,-1.436,,,0.536,T,A,0.27,-1.11,1.689,,63.64,HPP,-1.91433,0.100394,0.00555207,1.00031 kka2_1:8_S104S,kka2_1:8_104,Kka2,kka2_1:8,P00552,1.00031,NO,104,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.436,-1.436,,,0.536,T,A,0.27,-1.11,1.689,,63.64,HPP,-1.91433,0.100394,0.00555207,1.00031 beta-lactamase_156_A183G,beta-lactamase_156_183,TEM-1,beta-lactamase_156,P62593,1.00032,NO,183,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.231,-3.077,1.846,,0.155,H,A,0.46,-0.91,23.859,23.859,77.62,HHH,-1.53367,0.111618,0.00296631,1.00032 beta-lactamase_156_A185S,beta-lactamase_156_185,TEM-1,beta-lactamase_156,P62593,1.00032,NO,185,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.406,-3.291,1.885,,,H,A,0.46,-1.02,0.365,,65.03,HHP,-1.84033,0.111618,0.00467449,1.00032 beta-lactamase_156_E145L,beta-lactamase_156_145,TEM-1,beta-lactamase_156,P62593,1.00032,NO,145,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.357,-3.644,1.287,,0.545,H,A,1.04,0.79,3.661,,77.62,BAH,-2.069,0.111618,0.00553285,1.00032 beta-lactamase_K144I,beta-lactamase_144,TEM-1,beta-lactamase,P62593,1.00032,NO,144,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-2.388,-4.014,1.626,6.02507,0.863,H,A,2.81,1.27,0.515,,77.62,OBA,-1.904,0.221079,0.00481141,1.00032 beta-lactamase_M115L,beta-lactamase_115,TEM-1,beta-lactamase,P62593,1.00032,NO,115,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.389,-1.859,0.47,4.89743,0.019,E,B,1.3,0.08,1.236,,69.58,OHP,-1.25433,0.221079,0.0034337,1.00032 gb1_D272E,gb1_272,gb1,gb1,P06654,1.00032,NO,272,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.457,-1.962,0.505,,,,,,,0.234,,11.83,HAA,-1.54533,0.177985,0.00218257,1.00032 kka2_1:1_D157D,kka2_1:1_157,Kka2,kka2_1:1,P00552,1.00032,NO,157,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.993,-0.993,,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.520039,0.0042313,1.00032 kka2_1:1_F203F,kka2_1:1_203,Kka2,kka2_1:1,P00552,1.00032,NO,203,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-0.911,-0.911,,,0.26,E,B,0.58,-0.92,7.323,,63.64,BHP,-1.34167,0.520039,0.00318738,1.00032 kka2_1:1_Y218Y,kka2_1:1_218,Kka2,kka2_1:1,P00552,1.00032,NO,218,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-1.438,-1.438,,,0.122,H,A,1.25,-0.69,3.059,,56.06,BHP,-1.17533,0.520039,0.0126098,1.00032 kka2_1:2_R89R,kka2_1:2_89,Kka2,kka2_1:2,P00552,1.00032,NO,89,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.548,-1.548,,,0.209,E,B,1.2,1.41,14.396,14.396,64.39,OBA,-1.89867,0.295029,0.00524373,1.00032 beta-lactamase_625_K286L,beta-lactamase_625_286,TEM-1,beta-lactamase_625,P62593,1.00033,NO,286,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.213352,,1.00033 kka2_1:1_D134D,kka2_1:1_134,Kka2,kka2_1:1,P00552,1.00033,NO,134,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.969,-0.969,,,0.421,B,B,0.75,0.31,2.329,,49.62,HAB,-1.057,0.520039,0.00270812,1.00033 kka2_1:1_I196I,kka2_1:1_196,Kka2,kka2_1:1,P00552,1.00033,NO,196,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-2.115,-2.115,,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.520039,0.0107273,1.00033 kka2_1:1_P179P,kka2_1:1_179,Kka2,kka2_1:1,P00552,1.00033,NO,179,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.974,-0.974,,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.520039,0.00298346,1.00033 kka2_1:1_P249P,kka2_1:1_249,Kka2,kka2_1:1,P00552,1.00033,NO,249,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.867,-1.867,,,0.406,.,B,0.52,-0.01,8.037,8.037,92.05,HOA,-1.66867,0.520039,0.011045,1.00033 kka2_1:2_P98P,kka2_1:2_98,Kka2,kka2_1:2,P00552,1.00033,NO,98,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.526,-1.526,,,0.391,S,B,0.52,-0.65,2.82,,63.26,HOO,-1.19167,0.295029,0.00622754,1.00033 kka2_1:2_R38R,kka2_1:2_38,Kka2,kka2_1:2,P00552,1.00033,NO,38,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.207,-1.207,,,0.355,E,B,1.2,-1.13,6.872,6.872,52.27,HBH,-1.28567,0.295029,0.00372499,1.00033 kka2_1:8_R121R,kka2_1:8_121,Kka2,kka2_1:8,P00552,1.00033,NO,121,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.552,-1.552,,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.100394,0.00523326,1.00033 kka2_1:8_R121R,kka2_1:8_121,Kka2,kka2_1:8,P00552,1.00033,NO,121,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.552,-1.552,,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.100394,0.00523326,1.00033 kka2_1:8_R147R,kka2_1:8_147,Kka2,kka2_1:8,P00552,1.00033,NO,147,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.123,-1.123,,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.100394,0.00549168,1.00033 kka2_1:8_R147R,kka2_1:8_147,Kka2,kka2_1:8,P00552,1.00033,NO,147,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.123,-1.123,,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.100394,0.00549168,1.00033 beta-lactamase_156_R41L,beta-lactamase_156_41,TEM-1,beta-lactamase_156,P62593,1.00034,NO,41,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-0.942,-3.384,2.442,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.111618,0.00123327,1.00034 kka2_1:1_A255A,kka2_1:1_255,Kka2,kka2_1:1,P00552,1.00034,NO,255,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.715,-1.715,,,0.466,H,A,0.46,-0.52,0.946,,65.53,HHH,-1.71267,0.520039,0.0126809,1.00034 kka2_1:1_H135H,kka2_1:1_135,Kka2,kka2_1:1,P00552,1.00034,NO,135,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-1.331,-1.331,,,0.071,.,a,0.17,0.65,3.574,,53.03,ABP,-1.77367,0.520039,0.00532566,1.00034 kka2_1:1_I115I,kka2_1:1_115,Kka2,kka2_1:1,P00552,1.00034,NO,115,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.606,-1.606,,,0.105,H,A,0.48,-1.18,0.878,,65.53,PHH,-2.205,0.520039,0.00836567,1.00034 kka2_1:1_L260L,kka2_1:1_260,Kka2,kka2_1:1,P00552,1.00034,NO,260,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.741,-0.741,,,0.022,H,A,0.55,-0.52,,,,HHA,-0.845667,0.520039,0.0233782,1.00034 kka2_1:1_N195N,kka2_1:1_195,Kka2,kka2_1:1,P00552,1.00034,NO,195,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-0.836,-0.836,,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.520039,0.00276134,1.00034 kka2_1:1_R211R,kka2_1:1_211,Kka2,kka2_1:1,P00552,1.00034,NO,211,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-0.899,-0.899,,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.520039,0.00204888,1.00034 kka2_1:2_R253R,kka2_1:2_253,Kka2,kka2_1:2,P00552,1.00034,NO,253,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.356,-1.356,,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.295029,0.0144195,1.00034 kka2_1:4_M120M,kka2_1:4_120,Kka2,kka2_1:4,P00552,1.00034,NO,120,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-3.877,-3.877,,,,H,A,0.55,-0.42,2.259,,92.05,HHB,-2.16733,0.168804,0.00265808,1.00034 kka2_1:4_R121R,kka2_1:4_121,Kka2,kka2_1:4,P00552,1.00034,NO,121,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.552,-1.552,,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.168804,0.00523326,1.00034 kka2_1:4_V49V,kka2_1:4_49,Kka2,kka2_1:4,P00552,1.00034,NO,49,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.614,-1.614,,,,E,B,0.44,-0.77,1.233,,64.39,HHB,-1.3,0.168804,0.00615685,1.00034 kka2_1:8_Y218Y,kka2_1:8_218,Kka2,kka2_1:8,P00552,1.00034,NO,218,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-1.438,-1.438,,,0.122,H,A,1.25,-0.69,2.923,,56.06,BHP,-1.17533,0.100394,0.0126098,1.00034 kka2_1:8_Y218Y,kka2_1:8_218,Kka2,kka2_1:8,P00552,1.00034,NO,218,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-1.438,-1.438,,,0.122,H,A,1.25,-0.69,2.923,,56.06,BHP,-1.17533,0.100394,0.0126098,1.00034 beta-lactamase_156_E62R,beta-lactamase_156_62,TEM-1,beta-lactamase_156,P62593,1.00035,NO,62,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.193,-3.663,2.47,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.111618,0.00264802,1.00035 kka2_1:1_A215A,kka2_1:1_215,Kka2,kka2_1:1,P00552,1.00035,NO,215,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.968,-0.968,,,0.039,E,B,0.46,-0.59,0.754,,50.38,HHA,-1.00467,0.520039,0.00529129,1.00035 kka2_1:1_D216D,kka2_1:1_216,Kka2,kka2_1:1,P00552,1.00035,NO,216,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.785,-0.785,,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.520039,0.00229969,1.00035 kka2_1:1_G201G,kka2_1:1_201,Kka2,kka2_1:1,P00552,1.00035,NO,201,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.56,-1.56,,,0.149,T,l,0.29,-0.57,16.092,16.092,52.65,POB,-1.92233,0.520039,0.00820117,1.00035 kka2_1:1_V214V,kka2_1:1_214,Kka2,kka2_1:1,P00552,1.00035,NO,214,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.261,-1.261,,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.520039,0.00692782,1.00035 kka2_1:4_L39L,kka2_1:4_39,Kka2,kka2_1:4,P00552,1.00035,NO,39,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.223,-1.223,,,,E,B,0.55,-1.21,1.998,,71.59,BHP,-1.69167,0.168804,0.00493618,1.00035 Pab1_G177D,Pab1_177,Pab1,Pab1,P04147,1.00035,NO,177,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-2.24,-3.142,0.902,,,,,,,,,,AOH,-1.94067,0.175299,0.00170727,1.00035 beta-lactamase_156_H94Y,beta-lactamase_156_94,TEM-1,beta-lactamase_156,P62593,1.00036,NO,94,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-2.5,-4.209,1.709,,0.776,,B,0.17,1.24,11.583,11.583,77.62,HBH,-1.872,0.111618,0.00389226,1.00036 beta-lactamase_156_L219N,beta-lactamase_156_219,TEM-1,beta-lactamase_156,P62593,1.00036,NO,219,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.313,-4.217,2.904,,,I,A,0.55,-0.51,2.321,,74.48,HHB,-1.21533,0.111618,0.00664345,1.00036 beta-lactamase_625_A200Q,beta-lactamase_625_200,TEM-1,beta-lactamase_625,P62593,1.00036,NO,200,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.878,-3.113,1.235,,0.757,H,A,0.46,-0.19,12.672,12.672,77.62,HHP,-2.001,0.213352,0.0060056,1.00036 beta-lactamase_625_G226M,beta-lactamase_625_226,TEM-1,beta-lactamase_625,P62593,1.00036,NO,226,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.461,-4.924,3.463,,0.701,T,l,0.29,-0.25,3.199,,74.48,HOH,-1.42933,0.213352,0.00665294,1.00036 beta-lactamase_625_G76A,beta-lactamase_625_76,TEM-1,beta-lactamase_625,P62593,1.00036,NO,76,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.189,-1.531,0.342,,,H,A,0.29,-0.67,3.059,,67.83,OOH,-1.22267,0.213352,0.00476637,1.00036 kka2_1:1_A150A,kka2_1:1_150,Kka2,kka2_1:1,P00552,1.00036,NO,150,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.949,-0.949,,,0.544,T,A,0.46,1.34,2.333,,63.26,AHO,-1.272,0.520039,0.0045009,1.00036 kka2_1:1_V97V,kka2_1:1_97,Kka2,kka2_1:1,P00552,1.00036,NO,97,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.453,-1.453,,,0.083,,B,1.48,-0.83,13.576,13.576,53.03,AHO,-1.85067,0.520039,0.00737869,1.00036 kka2_1:2_K50K,kka2_1:2_50,Kka2,kka2_1:2,P00552,1.00036,NO,50,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-0.833,-0.833,,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.295029,0.00138626,1.00036 kka2_1:4_A34A,kka2_1:4_34,Kka2,kka2_1:4,P00552,1.00036,NO,34,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.928,-0.928,,,0.417,.,B,0.46,2.29,0.262,,52.27,AHH,-1.747,0.168804,0.00343484,1.00036 kka2_1:8_A191A,kka2_1:8_191,Kka2,kka2_1:8,P00552,1.00036,NO,191,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.831,-0.831,,,,,b,1.04,-0.94,1.306,,50,AHO,-0.868667,0.100394,0.00338807,1.00036 kka2_1:8_A191A,kka2_1:8_191,Kka2,kka2_1:8,P00552,1.00036,NO,191,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.831,-0.831,,,,,b,1.04,-0.94,1.306,,50,AHO,-0.868667,0.100394,0.00338807,1.00036 beta-lactamase_156_I54H,beta-lactamase_156_54,TEM-1,beta-lactamase_156,P62593,1.00037,NO,54,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-2.838,-3.42,0.582,,0.669,E,B,0.48,-0.14,0.541,,73.78,BHH,-2.337,0.111618,0.00403589,1.00037 beta-lactamase_156_L74A,beta-lactamase_156_74,TEM-1,beta-lactamase_156,P62593,1.00037,NO,74,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.296,-1.569,0.273,,,H,A,0.55,-0.91,0.746,,50,HHO,-1.34933,0.111618,0.00493255,1.00037 beta-lactamase_625_P143T,beta-lactamase_625_143,TEM-1,beta-lactamase_625,P62593,1.00037,NO,143,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.967,-2.616,1.649,,0.075,H,A,0.52,-0.37,1.445,,66.78,OOB,-1.354,0.213352,0.00114551,1.00037 beta-lactamase_625_P255A,beta-lactamase_625_255,TEM-1,beta-lactamase_625,P62593,1.00037,NO,255,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.213352,0.00499612,1.00037 beta-lactamase_625_P25T,beta-lactamase_625_25,TEM-1,beta-lactamase_625,P62593,1.00037,NO,25,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.526,-3.483,1.957,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.213352,0.00347571,1.00037 beta-lactamase_625_T126L,beta-lactamase_625_126,TEM-1,beta-lactamase_625,P62593,1.00037,NO,126,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.122,-3.373,2.251,,0.05,H,A,0.22,-0.05,0.817,,44.41,HPH,-1.60467,0.213352,0.00244552,1.00037 kka2_1:1_A117A,kka2_1:1_117,Kka2,kka2_1:1,P00552,1.00037,NO,117,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.828,-0.828,,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.520039,0.00282984,1.00037 kka2_1:1_C192C,kka2_1:1_192,Kka2,kka2_1:1,P00552,1.00037,NO,192,C,C,CC,Special,Special,5.07,5.07,0,0,121,121,0,108.5,108.5,0,-1.067,-1.067,,,0.095,.,B,0.46,-0.75,2.749,,50,HOH,-0.960333,0.520039,0.00485428,1.00037 kka2_1:1_D183D,kka2_1:1_183,Kka2,kka2_1:1,P00552,1.00037,NO,183,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.204,-1.204,,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.520039,0.00426304,1.00037 kka2_1:1_L223L,kka2_1:1_223,Kka2,kka2_1:1,P00552,1.00037,NO,223,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.861,-0.861,,,,H,A,0.55,-1.24,1.268,,50,HHH,-0.854333,0.520039,0.00253574,1.00037 kka2_1:1_V113V,kka2_1:1_113,Kka2,kka2_1:1,P00552,1.00037,NO,113,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.233,-1.233,,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.520039,0.00650191,1.00037 kka2_1:2_P12P,kka2_1:2_12,Kka2,kka2_1:2,P00552,1.00037,NO,12,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.853,-0.853,,,,.,B,0.52,1.25,0.261,,48.11,POH,-1.80767,0.295029,0.00500011,1.00037 kka2_1:4_L93L,kka2_1:4_93,Kka2,kka2_1:4,P00552,1.00037,NO,93,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.815,-0.815,,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.168804,0.00131498,1.00037 beta-lactamase_39_R220M,beta-lactamase_39_220,TEM-1,beta-lactamase_39,P62593,1.00038,NO,220,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-0.942,-4.506,3.564,,0.295,I,A,1.2,-0.76,1.596,,74.48,HBP,-1.33633,0.0495842,0.00232421,1.00038 kka2_1:1_D220D,kka2_1:1_220,Kka2,kka2_1:1,P00552,1.00038,NO,220,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.787,-0.787,,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.520039,0.00158066,1.00038 kka2_1:1_D250D,kka2_1:1_250,Kka2,kka2_1:1,P00552,1.00038,NO,250,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.015,-1.015,,,0.274,.,b,0.75,-0.46,4.177,,51.89,OAP,-1.83933,0.520039,0.0177103,1.00038 kka2_1:1_P128P,kka2_1:1_128,Kka2,kka2_1:1,P00552,1.00038,NO,128,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.922,-1.922,,,0.316,G,A,0.52,0.4,2.178,,56.06,AOH,-1.64733,0.520039,0.00774689,1.00038 kka2_1:1_P132P,kka2_1:1_132,Kka2,kka2_1:1,P00552,1.00038,NO,132,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.775,-0.775,,,0.692,.,A,0.52,0.56,0.224,,44.7,OOH,-0.825667,0.520039,0.0018489,1.00038 kka2_1:1_V153V,kka2_1:1_153,Kka2,kka2_1:1,P00552,1.00038,NO,153,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.092,-1.092,,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.520039,0.00501119,1.00038 kka2_1:8_L19L,kka2_1:8_19,Kka2,kka2_1:8,P00552,1.00038,NO,19,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.254,-1.254,,,0.08,T,A,1.59,-0.26,2.044,,65.53,BHH,-2.221,0.100394,0.00620703,1.00038 kka2_1:8_L19L,kka2_1:8_19,Kka2,kka2_1:8,P00552,1.00038,NO,19,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.254,-1.254,,,0.08,T,A,1.59,-0.26,2.044,,65.53,BHH,-2.221,0.100394,0.00620703,1.00038 beta-lactamase_156_I206T,beta-lactamase_156_206,TEM-1,beta-lactamase_156,P62593,1.00039,NO,206,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-2.429,-2.077,-0.352,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.111618,0.00528934,1.00039 beta-lactamase_625_G90Q,beta-lactamase_625_90,TEM-1,beta-lactamase_625,P62593,1.00039,NO,90,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-2.091,-2.862,0.771,,0.598,T,A,0.29,0.32,0.319,,77.62,HOB,-1.52633,0.213352,0.00490273,1.00039 beta-lactamase_625_T126Q,beta-lactamase_625_126,TEM-1,beta-lactamase_625,P62593,1.00039,NO,126,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.122,-3.945,2.823,,0.05,H,A,0.22,-0.05,0.817,,44.41,HPH,-1.60467,0.213352,0.00244552,1.00039 beta-lactamase_A170C,beta-lactamase_170,TEM-1,beta-lactamase,P62593,1.00039,NO,170,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.237,-4.736,3.499,5.19261,0.126,,L,2.34,-0.35,2.427,,64.69,AHH,-1.63267,0.221079,0.00431903,1.00039 beta-lactamase_E169T,beta-lactamase_169,TEM-1,beta-lactamase,P62593,1.00039,NO,169,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.23,-2.43,1.2,5.78896,0.337,,A,0.52,1,1.806,,73.08,PAH,-1.16533,0.221079,0.00400994,1.00039 beta-lactamase_E35E,beta-lactamase_35,TEM-1,beta-lactamase,P62593,1.00039,NO,35,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-0.869,-0.869,,5.10723,0.15,H,A,0.52,0.21,1.081,,46.85,HAA,-1.88667,0.221079,0.00174441,1.00039 kka2_1:1_M197M,kka2_1:1_197,Kka2,kka2_1:1,P00552,1.00039,NO,197,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.707,-1.707,,,0.121,E,B,1.59,-1.19,2.097,,65.53,HHH,-1.847,0.520039,0.00921295,1.00039 kka2_1:2_D101D,kka2_1:2_101,Kka2,kka2_1:2,P00552,1.00039,NO,101,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.028,-1.028,,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.295029,0.00423361,1.00039 kka2_1:2_P179P,kka2_1:2_179,Kka2,kka2_1:2,P00552,1.00039,NO,179,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.974,-0.974,,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.295029,0.00298346,1.00039 kka2_1:4_G88G,kka2_1:4_88,Kka2,kka2_1:4,P00552,1.00039,NO,88,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.689,-1.689,,,0.54,S,l,0.29,1.51,7.899,,65.53,HOB,-1.718,0.168804,0.00685559,1.00039 kka2_1:4_L103I,kka2_1:4_103,Kka2,kka2_1:4,P00552,1.00039,NO,103,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-2.362,-3.505,1.143,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.168804,0.00574792,1.00039 kka2_1:8_D227D,kka2_1:8_227,Kka2,kka2_1:8,P00552,1.00039,NO,227,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.758,-1.758,,,0.128,H,A,0.75,-0.63,0.281,,56.06,BAH,-1.43067,0.100394,0.00745029,1.00039 kka2_1:8_D227D,kka2_1:8_227,Kka2,kka2_1:8,P00552,1.00039,NO,227,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.758,-1.758,,,0.128,H,A,0.75,-0.63,0.281,,56.06,BAH,-1.43067,0.100394,0.00745029,1.00039 kka2_1:8_M148M,kka2_1:8_148,Kka2,kka2_1:8,P00552,1.00039,NO,148,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.847,-1.847,,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.100394,0.00982664,1.00039 kka2_1:8_M148M,kka2_1:8_148,Kka2,kka2_1:8,P00552,1.00039,NO,148,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.847,-1.847,,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.100394,0.00982664,1.00039 kka2_1:8_R89R,kka2_1:8_89,Kka2,kka2_1:8,P00552,1.00039,NO,89,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.548,-1.548,,,0.209,E,B,1.2,1.41,25.3,25.3,64.39,OBA,-1.89867,0.100394,0.00524373,1.00039 kka2_1:8_R89R,kka2_1:8_89,Kka2,kka2_1:8,P00552,1.00039,NO,89,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.548,-1.548,,,0.209,E,B,1.2,1.41,25.3,25.3,64.39,OBA,-1.89867,0.100394,0.00524373,1.00039 beta-lactamase_156_V31A,beta-lactamase_156_31,TEM-1,beta-lactamase_156,P62593,1.0004,NO,31,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.822,-2.265,0.443,,,H,A,0.44,-0.46,4.126,,73.78,BHB,-2.03767,0.111618,0.00478065,1.0004 beta-lactamase_625_A225H,beta-lactamase_625_225,TEM-1,beta-lactamase_625,P62593,1.0004,NO,225,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.845,-3.109,1.264,,1,T,B,0.46,-0.38,9.874,9.874,74.48,OHO,-1.39967,0.213352,0.00465057,1.0004 beta-lactamase_625_A247V,beta-lactamase_625_247,TEM-1,beta-lactamase_625,P62593,1.0004,NO,247,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.213352,0.00611275,1.0004 kka2_1:1_A237A,kka2_1:1_237,Kka2,kka2_1:1,P00552,1.0004,NO,237,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.12,-2.12,,,0.068,H,A,0.46,-0.71,2.369,,92.05,HHA,-2.10433,0.520039,0.012257,1.0004 kka2_1:1_L259L,kka2_1:1_259,Kka2,kka2_1:1,P00552,1.0004,NO,259,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.088,-1.088,,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.520039,0.0206964,1.0004 kka2_1:1_W15W,kka2_1:1_15,Kka2,kka2_1:1,P00552,1.0004,NO,15,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-1.392,-1.392,,,0.01,G,A,0.47,0.15,20.149,20.149,52.27,HHH,-2.10533,0.520039,0.00585505,1.0004 kka2_1:2_E182E,kka2_1:2_182,Kka2,kka2_1:2,P00552,1.0004,NO,182,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.516,-1.516,,,0.326,,B,1.52,0.75,14.547,14.547,65.53,OAA,-1.806,0.295029,0.00641548,1.0004 kka2_1:2_W15W,kka2_1:2_15,Kka2,kka2_1:2,P00552,1.0004,NO,15,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-1.392,-1.392,,,0.01,G,A,0.47,0.15,2.586,,52.27,HHH,-2.10533,0.295029,0.00585505,1.0004 kka2_1:4_D227D,kka2_1:4_227,Kka2,kka2_1:4,P00552,1.0004,NO,227,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.758,-1.758,,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.168804,0.00745029,1.0004 kka2_1:4_D82D,kka2_1:4_82,Kka2,kka2_1:4,P00552,1.0004,NO,82,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.946,-1.946,,,0.341,E,b,0.75,0.52,11.923,11.923,63.64,HAH,-1.98,0.168804,0.00637516,1.0004 kka2_1:4_Y218Y,kka2_1:4_218,Kka2,kka2_1:4,P00552,1.0004,NO,218,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-1.438,-1.438,,,0.122,H,A,0.21,-0.69,1.022,,56.06,BHP,-1.17533,0.168804,0.0126098,1.0004 beta-lactamase_0_M153G,beta-lactamase_0_153,TEM-1,beta-lactamase_0,P62593,1.00041,NO,153,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-3.193,-3.633,0.44,,0.14,T,A,0.55,-0.11,3.826,,77.62,PHO,-2.25767,0.0500837,0.00509109,1.00041 beta-lactamase_39_N98K,beta-lactamase_39_98,TEM-1,beta-lactamase_39,P62593,1.00041,NO,98,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-2.973,-2.653,-0.32,,0.963,G,A,0.61,1.35,14.853,14.853,77.62,PPA,-2.07867,0.0495842,0.00505389,1.00041 kka2_1:2_F133F,kka2_1:2_133,Kka2,kka2_1:2,P00552,1.00041,NO,133,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-0.871,-0.871,,,0.178,.,B,0.58,0.43,1.999,,42.42,OHA,-0.871667,0.295029,0.00182168,1.00041 kka2_1:2_Y218Y,kka2_1:2_218,Kka2,kka2_1:2,P00552,1.00041,NO,218,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-1.438,-1.438,,,0.122,H,A,0.21,-0.69,1.022,,56.06,BHP,-1.17533,0.295029,0.0126098,1.00041 kka2_1:8_D183D,kka2_1:8_183,Kka2,kka2_1:8,P00552,1.00041,NO,183,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.204,-1.204,,,0.518,.,b,0.75,0.25,0.347,,52.27,AAH,-1.40533,0.100394,0.00426304,1.00041 kka2_1:8_D183D,kka2_1:8_183,Kka2,kka2_1:8,P00552,1.00041,NO,183,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.204,-1.204,,,0.518,.,b,0.75,0.25,0.347,,52.27,AAH,-1.40533,0.100394,0.00426304,1.00041 kka2_1:8_V198V,kka2_1:8_198,Kka2,kka2_1:8,P00552,1.00041,NO,198,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.719,-1.719,,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.100394,0.00835002,1.00041 kka2_1:8_V198V,kka2_1:8_198,Kka2,kka2_1:8,P00552,1.00041,NO,198,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.719,-1.719,,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.100394,0.00835002,1.00041 kka2_1:8_W24W,kka2_1:8_24,Kka2,kka2_1:8,P00552,1.00041,NO,24,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-1.779,-1.779,,,0.477,E,B,1.51,-0.21,2.503,,56.06,AHH,-2.24467,0.100394,0.00631564,1.00041 kka2_1:8_W24W,kka2_1:8_24,Kka2,kka2_1:8,P00552,1.00041,NO,24,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-1.779,-1.779,,,0.477,E,B,1.51,-0.21,2.503,,56.06,AHH,-2.24467,0.100394,0.00631564,1.00041 beta-lactamase_2500_E195S,beta-lactamase_2500_195,TEM-1,beta-lactamase_2500,P62593,1.00042,NO,195,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.186,-2.512,0.326,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.361275,0.00496565,1.00042 beta-lactamase_39_E35S,beta-lactamase_39_35,TEM-1,beta-lactamase_39,P62593,1.00042,NO,35,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-0.869,-3.186,2.317,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.0495842,0.00174441,1.00042 beta-lactamase_625_L137V,beta-lactamase_625_137,TEM-1,beta-lactamase_625,P62593,1.00042,NO,137,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.03,-2.816,1.786,,,H,A,0.55,-0.38,1.5,,42.31,HHP,-1.58933,0.213352,0.00278599,1.00042 beta-lactamase_625_R81F,beta-lactamase_625_81,TEM-1,beta-lactamase_625,P62593,1.00042,NO,81,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.466,-4.359,2.893,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.213352,0.00499763,1.00042 kka2_1:1_A224A,kka2_1:1_224,Kka2,kka2_1:1,P00552,1.00042,NO,224,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.977,-0.977,,,,H,A,0.46,-1.26,1.725,,63.64,HHP,-1.41033,0.520039,0.00352047,1.00042 kka2_1:1_G151G,kka2_1:1_151,Kka2,kka2_1:1,P00552,1.00042,NO,151,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.873,-0.873,,,0.678,T,l,0.29,1.36,0.226,,49.62,HOH,-1.11433,0.520039,0.00339918,1.00042 kka2_1:1_Q100Q,kka2_1:1_100,Kka2,kka2_1:1,P00552,1.00042,NO,100,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.77,-2.77,,,0.646,E,B,0.4,-0.79,15.116,15.116,71.59,OPA,-1.46467,0.520039,0.0066405,1.00042 kka2_1:2_A229A,kka2_1:2_229,Kka2,kka2_1:2,P00552,1.00042,NO,229,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.739,-1.739,,,0.32,H,A,0.46,-0.7,6.549,,63.64,HHA,-1.851,0.295029,0.00942138,1.00042 kka2_1:2_L94L,kka2_1:2_94,Kka2,kka2_1:2,P00552,1.00042,NO,94,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.618,-1.618,,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.295029,0.00520888,1.00042 kka2_1:4_A150E,kka2_1:4_150,Kka2,kka2_1:4,P00552,1.00042,NO,150,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.949,-2.676,1.727,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.168804,0.0045009,1.00042 kka2_1:4_L92L,kka2_1:4_92,Kka2,kka2_1:4,P00552,1.00042,NO,92,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.893,-0.893,,,0.007,E,B,0.55,-0.19,1.447,,63.26,HHH,-0.962,0.168804,0.00307177,1.00042 kka2_1:4_R38R,kka2_1:4_38,Kka2,kka2_1:4,P00552,1.00042,NO,38,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.207,-1.207,,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.168804,0.00372499,1.00042 beta-lactamase_156_S122G,beta-lactamase_156_122,TEM-1,beta-lactamase_156,P62593,1.00043,NO,122,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.406,-3.475,1.069,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.111618,0.00497825,1.00043 beta-lactamase_39_T198P,beta-lactamase_39_198,TEM-1,beta-lactamase_39,P62593,1.00043,NO,198,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.168,-2.894,0.726,,0.489,,B,0.22,-0.13,3.614,,73.78,HPH,-1.98767,0.0495842,0.004311,1.00043 kka2_1:1_R147R,kka2_1:1_147,Kka2,kka2_1:1,P00552,1.00043,NO,147,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.123,-1.123,,,0.094,H,A,1.2,0.97,2.578,,64.02,PBH,-1.98267,0.520039,0.00549168,1.00043 kka2_1:8_D62D,kka2_1:8_62,Kka2,kka2_1:8,P00552,1.00043,NO,62,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.591,-1.591,,,0.262,H,A,0.29,0.08,5.58,,64.39,PAA,-1.77833,0.100394,0.00744243,1.00043 kka2_1:8_D62D,kka2_1:8_62,Kka2,kka2_1:8,P00552,1.00043,NO,62,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.591,-1.591,,,0.262,H,A,0.29,0.08,5.58,,64.39,PAA,-1.77833,0.100394,0.00744243,1.00043 beta-lactamase_156_A183L,beta-lactamase_156_183,TEM-1,beta-lactamase_156,P62593,1.00044,NO,183,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.231,-3.283,2.052,,0.155,H,A,0.46,-0.91,23.859,23.859,77.62,HHH,-1.53367,0.111618,0.00296631,1.00044 beta-lactamase_39_I280T,beta-lactamase_39_280,TEM-1,beta-lactamase_39,P62593,1.00044,NO,280,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.0495842,0.0530888,1.00044 beta-lactamase_39_M270R,beta-lactamase_39_270,TEM-1,beta-lactamase_39,P62593,1.00044,NO,270,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.0495842,0.00767762,1.00044 beta-lactamase_A182S,beta-lactamase_182,TEM-1,beta-lactamase,P62593,1.00044,NO,182,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.777,-2.825,1.048,4.98609,0.136,H,A,0.52,-0.66,2.032,,93.01,OHH,-1.27367,0.221079,0.00559099,1.00044 kka2_1:1_A144A,kka2_1:1_144,Kka2,kka2_1:1,P00552,1.00044,NO,144,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.859,-0.859,,,,H,A,0.46,0.21,0.842,,52.65,BHB,-1.72933,0.520039,0.00231095,1.00044 kka2_1:1_R253R,kka2_1:1_253,Kka2,kka2_1:1,P00552,1.00044,NO,253,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.356,-1.356,,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.520039,0.0144195,1.00044 kka2_1:2_L184L,kka2_1:2_184,Kka2,kka2_1:2,P00552,1.00044,NO,184,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.496,-1.496,,,0.489,E,B,0.55,-0.06,14.044,14.044,63.26,AHH,-1.24833,0.295029,0.00518742,1.00044 kka2_1:4_D101D,kka2_1:4_101,Kka2,kka2_1:4,P00552,1.00044,NO,101,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.028,-1.028,,,0.213,E,B,0.75,-1.24,8.707,,63.64,PAH,-1.534,0.168804,0.00423361,1.00044 kka2_1:8_D90D,kka2_1:8_90,Kka2,kka2_1:8,P00552,1.00044,NO,90,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.459,-2.459,,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.100394,0.00583842,1.00044 kka2_1:8_D90D,kka2_1:8_90,Kka2,kka2_1:8,P00552,1.00044,NO,90,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.459,-2.459,,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.100394,0.00583842,1.00044 kka2_1:8_G88G,kka2_1:8_88,Kka2,kka2_1:8,P00552,1.00044,NO,88,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.689,-1.689,,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.100394,0.00685559,1.00044 kka2_1:8_G88G,kka2_1:8_88,Kka2,kka2_1:8,P00552,1.00044,NO,88,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.689,-1.689,,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.100394,0.00685559,1.00044 kka2_1:8_L184L,kka2_1:8_184,Kka2,kka2_1:8,P00552,1.00044,NO,184,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.496,-1.496,,,0.489,E,B,0.55,-0.06,4.495,,63.26,AHH,-1.24833,0.100394,0.00518742,1.00044 kka2_1:8_L184L,kka2_1:8_184,Kka2,kka2_1:8,P00552,1.00044,NO,184,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.496,-1.496,,,0.489,E,B,0.55,-0.06,4.495,,63.26,AHH,-1.24833,0.100394,0.00518742,1.00044 kka2_1:8_V49V,kka2_1:8_49,Kka2,kka2_1:8,P00552,1.00044,NO,49,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.614,-1.614,,,,E,B,1.48,-0.77,1.31,,64.39,HHB,-1.3,0.100394,0.00615685,1.00044 kka2_1:8_V49V,kka2_1:8_49,Kka2,kka2_1:8,P00552,1.00044,NO,49,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.614,-1.614,,,,E,B,1.48,-0.77,1.31,,64.39,HHB,-1.3,0.100394,0.00615685,1.00044 beta-lactamase_156_G236T,beta-lactamase_156_236,TEM-1,beta-lactamase_156,P62593,1.00045,NO,236,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.784,-3.55,2.766,,0.241,,b,0.29,-0.59,1.883,,64.69,HOO,-1.025,0.111618,0.00162372,1.00045 beta-lactamase_156_R273Y,beta-lactamase_156_273,TEM-1,beta-lactamase_156,P62593,1.00045,NO,273,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.314,-4.336,2.022,,0.564,H,A,1.2,1.57,20.248,20.248,73.78,ABP,-1.841,0.111618,0.0077952,1.00045 kka2_1:1_L193L,kka2_1:1_193,Kka2,kka2_1:1,P00552,1.00045,NO,193,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.983,-0.983,,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.520039,0.00480179,1.00045 kka2_1:1_P194P,kka2_1:1_194,Kka2,kka2_1:1,P00552,1.00045,NO,194,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.846,-0.846,,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.520039,0.00314194,1.00045 kka2_1:2_R147R,kka2_1:2_147,Kka2,kka2_1:2,P00552,1.00045,NO,147,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.123,-1.123,,,0.094,H,A,1.2,0.97,0.425,,64.02,PBH,-1.98267,0.295029,0.00549168,1.00045 beta-lactamase_156_L135N,beta-lactamase_156_135,TEM-1,beta-lactamase_156,P62593,1.00046,NO,135,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.002,-4.152,3.15,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.111618,0.00244423,1.00046 beta-lactamase_156_V82C,beta-lactamase_156_82,TEM-1,beta-lactamase_156,P62593,1.00046,NO,82,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.325,-4.774,3.449,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.111618,0.00397046,1.00046 kka2_1:1_H188H,kka2_1:1_188,Kka2,kka2_1:1,P00552,1.00046,NO,188,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-0.913,-0.913,,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.520039,0.00273139,1.00046 kka2_1:1_L174L,kka2_1:1_174,Kka2,kka2_1:1,P00552,1.00046,NO,174,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.952,-0.952,,,,H,A,0.55,-0.31,13.276,13.276,51.89,BHB,-2.08533,0.520039,0.00438501,1.00046 kka2_1:1_M116M,kka2_1:1_116,Kka2,kka2_1:1,P00552,1.00046,NO,116,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-2.482,-2.482,,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.520039,0.00745147,1.00046 kka2_1:1_Q136Q,kka2_1:1_136,Kka2,kka2_1:1,P00552,1.00046,NO,136,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-3.021,-3.021,,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.520039,0.00624149,1.00046 kka2_1:1_V198V,kka2_1:1_198,Kka2,kka2_1:1,P00552,1.00046,NO,198,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.719,-1.719,,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.520039,0.00835002,1.00046 kka2_1:2_K112K,kka2_1:2_112,Kka2,kka2_1:2,P00552,1.00046,NO,112,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-2.491,-2.491,,,0.076,H,A,2.34,-1.37,23.433,23.433,56.06,ABH,-2.00133,0.295029,0.00645389,1.00046 kka2_1:2_V214V,kka2_1:2_214,Kka2,kka2_1:2,P00552,1.00046,NO,214,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.261,-1.261,,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.295029,0.00692782,1.00046 kka2_1:4_F171F,kka2_1:4_171,Kka2,kka2_1:4,P00552,1.00046,NO,171,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.326,-1.326,,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.168804,0.00821426,1.00046 kka2_1:4_L70L,kka2_1:4_70,Kka2,kka2_1:4,P00552,1.00046,NO,70,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.017,-1.017,,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.168804,0.00411884,1.00046 kka2_1:8_P132P,kka2_1:8_132,Kka2,kka2_1:8,P00552,1.00046,NO,132,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.775,-0.775,,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.100394,0.0018489,1.00046 kka2_1:8_P132P,kka2_1:8_132,Kka2,kka2_1:8,P00552,1.00046,NO,132,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.775,-0.775,,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.100394,0.0018489,1.00046 kka2_1:8_R38R,kka2_1:8_38,Kka2,kka2_1:8,P00552,1.00046,NO,38,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.207,-1.207,,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.100394,0.00372499,1.00046 kka2_1:8_R38R,kka2_1:8_38,Kka2,kka2_1:8,P00552,1.00046,NO,38,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.207,-1.207,,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.100394,0.00372499,1.00046 beta-lactamase_2500_T112D,beta-lactamase_2500_112,TEM-1,beta-lactamase_2500,P62593,1.00047,NO,112,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.186,-2.66,0.474,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.361275,0.00531334,1.00047 beta-lactamase_625_V82C,beta-lactamase_625_82,TEM-1,beta-lactamase_625,P62593,1.00047,NO,82,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.325,-4.774,3.449,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.213352,0.00397046,1.00047 kka2_1:2_L123L,kka2_1:2_123,Kka2,kka2_1:2,P00552,1.00047,NO,123,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.888,-0.888,,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.295029,0.00325188,1.00047 kka2_1:2_M116M,kka2_1:2_116,Kka2,kka2_1:2,P00552,1.00047,NO,116,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-2.482,-2.482,,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.295029,0.00745147,1.00047 kka2_1:2_P128P,kka2_1:2_128,Kka2,kka2_1:2,P00552,1.00047,NO,128,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.922,-1.922,,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.295029,0.00774689,1.00047 kka2_1:2_R66R,kka2_1:2_66,Kka2,kka2_1:2,P00552,1.00047,NO,66,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-0.922,-0.922,,,0.103,H,A,1.2,-0.2,2.659,,46.21,HBH,-1.13567,0.295029,0.00161025,1.00047 beta-lactamase_2500_H151V,beta-lactamase_2500_151,TEM-1,beta-lactamase_2500,P62593,1.00048,NO,151,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-2.96,-3.785,0.825,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.361275,0.00216946,1.00048 beta-lactamase_39_S104Q,beta-lactamase_39_104,TEM-1,beta-lactamase_39,P62593,1.00048,NO,104,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.015,-3.815,2.8,,0.04,,b,0.27,0.57,4.02,,63.29,HPO,-1.05267,0.0495842,0.00218083,1.00048 beta-lactamase_625_K109V,beta-lactamase_625_109,TEM-1,beta-lactamase_625,P62593,1.00048,NO,109,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.734,-3.727,1.993,,0.787,G,A,2.34,2.21,7.243,,72.73,ABB,-1.63333,0.213352,0.00462493,1.00048 beta-lactamase_625_P60V,beta-lactamase_625_60,TEM-1,beta-lactamase_625,P62593,1.00048,NO,60,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-2.469,-3.507,1.038,,0.256,T,A,0.52,-0.56,3.653,,77.62,BOA,-1.97633,0.213352,0.00521318,1.00048 beta-lactamase_625_Q276N,beta-lactamase_625_276,TEM-1,beta-lactamase_625,P62593,1.00048,NO,276,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.213352,0.0191712,1.00048 gb1_V255F,gb1_255,gb1,gb1,P06654,1.00048,NO,255,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-3.127,-3.455,0.328,,,,,,,1.323,,45.54,BHH,-2.03867,0.177985,0.00408354,1.00048 kka2_1:1_A222A,kka2_1:1_222,Kka2,kka2_1:1,P00552,1.00048,NO,222,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.725,-0.725,,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.520039,0.00207657,1.00048 kka2_1:1_L94L,kka2_1:1_94,Kka2,kka2_1:1,P00552,1.00048,NO,94,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.618,-1.618,,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.520039,0.00520888,1.00048 kka2_1:1_W236W,kka2_1:1_236,Kka2,kka2_1:1,P00552,1.00048,NO,236,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-1.363,-1.363,,,0.303,H,A,1.51,-0.76,12.263,12.263,48.48,AHH,-1.81267,0.520039,0.0088796,1.00048 kka2_1:2_L102L,kka2_1:2_102,Kka2,kka2_1:2,P00552,1.00048,NO,102,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.804,-0.804,,,,T,A,1.59,-1.17,4.258,,42.42,AHH,-1.398,0.295029,0.00201332,1.00048 kka2_1:2_V198V,kka2_1:2_198,Kka2,kka2_1:2,P00552,1.00048,NO,198,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.719,-1.719,,,0.05,E,B,1.48,-0.95,1.074,,56.06,HHA,-1.88667,0.295029,0.00835002,1.00048 kka2_1:8_D82D,kka2_1:8_82,Kka2,kka2_1:8,P00552,1.00048,NO,82,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.946,-1.946,,,0.341,E,b,0.29,0.52,7.463,,63.64,HAH,-1.98,0.100394,0.00637516,1.00048 kka2_1:8_D82D,kka2_1:8_82,Kka2,kka2_1:8,P00552,1.00048,NO,82,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.946,-1.946,,,0.341,E,b,0.29,0.52,7.463,,63.64,HAH,-1.98,0.100394,0.00637516,1.00048 kka2_1:8_G201G,kka2_1:8_201,Kka2,kka2_1:8,P00552,1.00048,NO,201,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.56,-1.56,,,0.149,T,l,0.75,-0.57,2.152,,52.65,POB,-1.92233,0.100394,0.00820117,1.00048 kka2_1:8_G201G,kka2_1:8_201,Kka2,kka2_1:8,P00552,1.00048,NO,201,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.56,-1.56,,,0.149,T,l,0.75,-0.57,2.152,,52.65,POB,-1.92233,0.100394,0.00820117,1.00048 beta-lactamase_156_L47M,beta-lactamase_156_47,TEM-1,beta-lactamase_156,P62593,1.00049,NO,47,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.876,-2.629,0.753,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.111618,0.00439844,1.00049 beta-lactamase_625_N173C,beta-lactamase_625_173,TEM-1,beta-lactamase_625,P62593,1.00049,NO,173,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-2.663,-5.092,2.429,,1.044,T,l,0.61,1.25,1.426,,77.62,OPA,-1.46633,0.213352,0.0033769,1.00049 kka2_1:1_R258R,kka2_1:1_258,Kka2,kka2_1:1,P00552,1.00049,NO,258,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.626,-1.626,,,0.316,H,A,1.2,-0.85,7.485,7.485,53.03,HBH,-1.25933,0.520039,0.00983174,1.00049 kka2_1:8_L39L,kka2_1:8_39,Kka2,kka2_1:8,P00552,1.00049,NO,39,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.223,-1.223,,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.100394,0.00493618,1.00049 kka2_1:8_L39L,kka2_1:8_39,Kka2,kka2_1:8,P00552,1.00049,NO,39,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.223,-1.223,,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.100394,0.00493618,1.00049 kka2_1:8_L93L,kka2_1:8_93,Kka2,kka2_1:8,P00552,1.00049,NO,93,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.815,-0.815,,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.100394,0.00131498,1.00049 kka2_1:8_L93L,kka2_1:8_93,Kka2,kka2_1:8,P00552,1.00049,NO,93,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.815,-0.815,,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.100394,0.00131498,1.00049 kka2_1:8_Y22Y,kka2_1:8_22,Kka2,kka2_1:8,P00552,1.00049,NO,22,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-1.583,-1.583,,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.100394,0.00598977,1.00049 kka2_1:8_Y22Y,kka2_1:8_22,Kka2,kka2_1:8,P00552,1.00049,NO,22,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-1.583,-1.583,,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.100394,0.00598977,1.00049 kka2_1:8_Y244Y,kka2_1:8_244,Kka2,kka2_1:8,P00552,1.00049,NO,244,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-0.775,-0.775,,,0.066,H,A,1.25,-0.64,,,,HHO,-1.41267,0.100394,0.00453187,1.00049 kka2_1:8_Y244Y,kka2_1:8_244,Kka2,kka2_1:8,P00552,1.00049,NO,244,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-0.775,-0.775,,,0.066,H,A,1.25,-0.64,,,,HHO,-1.41267,0.100394,0.00453187,1.00049 beta-lactamase_156_L28T,beta-lactamase_156_28,TEM-1,beta-lactamase_156,P62593,1.0005,NO,28,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.579,-3.444,1.865,,0.277,H,A,0.55,-0.16,3.262,,93.01,PHH,-2.11333,0.111618,0.00359321,1.0005 beta-lactamase_156_T126W,beta-lactamase_156_126,TEM-1,beta-lactamase_156,P62593,1.0005,NO,126,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.122,-5.243,4.121,,0.05,H,A,0.22,-0.05,1.14,,44.41,HPH,-1.60467,0.111618,0.00244552,1.0005 beta-lactamase_2500_Y95F,beta-lactamase_2500_95,TEM-1,beta-lactamase_2500,P62593,1.0005,NO,95,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-1.715,-2.096,0.381,,0.122,,b,0.21,-0.37,2.914,,77.62,BHP,-2.16167,0.361275,0.00479449,1.0005 kka2_1:1_D208D,kka2_1:1_208,Kka2,kka2_1:1,P00552,1.0005,NO,208,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.708,-0.708,,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.520039,0.00212588,1.0005 kka2_1:4_C209C,kka2_1:4_209,Kka2,kka2_1:4,P00552,1.0005,NO,209,C,C,CC,Special,Special,5.07,5.07,0,0,121,121,0,108.5,108.5,0,-0.906,-0.906,,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.168804,0.00260862,1.0005 kka2_1:4_D183D,kka2_1:4_183,Kka2,kka2_1:4,P00552,1.0005,NO,183,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.204,-1.204,,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.168804,0.00426304,1.0005 kka2_1:4_E59E,kka2_1:4_59,Kka2,kka2_1:4,P00552,1.0005,NO,59,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-0.952,-0.952,,,0.187,.,L,1.04,0.62,3.408,,50.38,PAH,-1.53,0.168804,0.00280355,1.0005 kka2_1:4_F256F,kka2_1:4_256,Kka2,kka2_1:4,P00552,1.0005,NO,256,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.49,-1.49,,,,H,A,0.58,-0.78,1.653,,53.03,HHH,-1.423,0.168804,0.0132841,1.0005 kka2_1:4_L126L,kka2_1:4_126,Kka2,kka2_1:4,P00552,1.0005,NO,126,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.246,-1.246,,,0.285,S,B,0.55,0.12,0.302,,51.89,PHA,-1.744,0.168804,0.0066485,1.0005 Pab1_E175R,Pab1_175,Pab1,Pab1,P04147,1.0005,NO,175,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.055,-3.682,1.627,,,,,,,,,,AAA,-1.82667,0.175299,0.00203137,1.0005 kka2_1:2_G30G,kka2_1:2_30,Kka2,kka2_1:2,P00552,1.00051,NO,30,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.596,-0.596,,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.295029,0.00159208,1.00051 kka2_1:2_L107L,kka2_1:2_107,Kka2,kka2_1:2,P00552,1.00051,NO,107,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.238,-1.238,,,0.197,,B,1.59,-1.1,2.68,,71.59,BHH,-2.143,0.295029,0.00561937,1.00051 kka2_1:2_L170L,kka2_1:2_170,Kka2,kka2_1:2,P00552,1.00051,NO,170,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.28,-1.28,,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.295029,0.00730791,1.00051 kka2_1:2_V36V,kka2_1:2_36,Kka2,kka2_1:2,P00552,1.00051,NO,36,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-0.898,-0.898,,,0.292,E,B,1.48,0.21,1.064,,52.27,HHH,-1.484,0.295029,0.00245633,1.00051 kka2_1:8_D101D,kka2_1:8_101,Kka2,kka2_1:8,P00552,1.00051,NO,101,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.028,-1.028,,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.100394,0.00423361,1.00051 kka2_1:8_D101D,kka2_1:8_101,Kka2,kka2_1:8,P00552,1.00051,NO,101,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.028,-1.028,,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.100394,0.00423361,1.00051 kka2_1:8_E182E,kka2_1:8_182,Kka2,kka2_1:8,P00552,1.00051,NO,182,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.516,-1.516,,,0.326,,B,1.52,0.75,2.568,,65.53,OAA,-1.806,0.100394,0.00641548,1.00051 kka2_1:8_E182E,kka2_1:8_182,Kka2,kka2_1:8,P00552,1.00051,NO,182,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.516,-1.516,,,0.326,,B,1.52,0.75,2.568,,65.53,OAA,-1.806,0.100394,0.00641548,1.00051 kka2_1:8_M120M,kka2_1:8_120,Kka2,kka2_1:8,P00552,1.00051,NO,120,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-3.877,-3.877,,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.100394,0.00265808,1.00051 kka2_1:8_M120M,kka2_1:8_120,Kka2,kka2_1:8,P00552,1.00051,NO,120,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-3.877,-3.877,,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.100394,0.00265808,1.00051 kka2_1:8_Q219Q,kka2_1:8_219,Kka2,kka2_1:8,P00552,1.00051,NO,219,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-0.93,-0.93,,,0.088,H,A,0.4,-0.85,0.897,,50,HPA,-1.05167,0.100394,0.00237913,1.00051 kka2_1:8_Q219Q,kka2_1:8_219,Kka2,kka2_1:8,P00552,1.00051,NO,219,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-0.93,-0.93,,,0.088,H,A,0.4,-0.85,0.897,,50,HPA,-1.05167,0.100394,0.00237913,1.00051 kka2_1:8_R140R,kka2_1:8_140,Kka2,kka2_1:8,P00552,1.00051,NO,140,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.351,-1.351,,,0.12,H,A,0.16,0.2,2.874,,53.03,BBH,-1.885,0.100394,0.00430167,1.00051 kka2_1:8_R140R,kka2_1:8_140,Kka2,kka2_1:8,P00552,1.00051,NO,140,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.351,-1.351,,,0.12,H,A,0.16,0.2,2.874,,53.03,BBH,-1.885,0.100394,0.00430167,1.00051 beta-lactamase_156_G141A,beta-lactamase_156_141,TEM-1,beta-lactamase_156,P62593,1.00052,NO,141,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.828,-2.988,2.16,,0.575,T,l,0.29,-0.28,0.198,,64.69,HOO,-1.08933,0.111618,0.0012419,1.00052 beta-lactamase_2500_P25Y,beta-lactamase_2500_25,TEM-1,beta-lactamase_2500,P62593,1.00052,NO,25,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.526,-4.327,2.801,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.361275,0.00347571,1.00052 beta-lactamase_H151Q,beta-lactamase_151,TEM-1,beta-lactamase,P62593,1.00052,NO,151,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-2.96,-2.497,-0.463,5.47408,0.594,H,A,0.35,0.1,1.843,,77.62,HBP,-2.34767,0.221079,0.00216946,1.00052 kka2_1:1_G205G,kka2_1:1_205,Kka2,kka2_1:1,P00552,1.00052,NO,205,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.596,-0.596,,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.520039,0.00221855,1.00052 kka2_1:1_R217R,kka2_1:1_217,Kka2,kka2_1:1,P00552,1.00052,NO,217,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.158,-1.158,,,0.252,T,A,1.2,-0.59,0.381,,52.27,ABH,-1.127,0.520039,0.0047191,1.00052 beta-lactamase_156_S256P,beta-lactamase_156_256,TEM-1,beta-lactamase_156,P62593,1.00053,NO,256,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.111618,0.00710634,1.00053 beta-lactamase_Q88D,beta-lactamase_88,TEM-1,beta-lactamase,P62593,1.00053,NO,88,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.086,-2.035,-0.051,5.8056,0.807,,B,0.12,2.03,1.84,,77.62,APH,-1.53433,0.221079,0.00504167,1.00053 kka2_1:2_N200N,kka2_1:2_200,Kka2,kka2_1:2,P00552,1.00053,NO,200,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-2.446,-2.446,,,0.756,T,L,0.61,-0.08,2.836,,64.39,APO,-2.08,0.295029,0.00838549,1.00053 kka2_1:4_Y22Y,kka2_1:4_22,Kka2,kka2_1:4,P00552,1.00053,NO,22,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-1.583,-1.583,,,0.122,.,B,0.21,-0.8,1.838,,65.53,OHA,-1.80333,0.168804,0.00598977,1.00053 kka2_1:8_L92L,kka2_1:8_92,Kka2,kka2_1:8,P00552,1.00053,NO,92,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.893,-0.893,,,0.007,E,B,1.59,-0.19,1.719,,63.26,HHH,-0.962,0.100394,0.00307177,1.00053 kka2_1:8_L92L,kka2_1:8_92,Kka2,kka2_1:8,P00552,1.00053,NO,92,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.893,-0.893,,,0.007,E,B,1.59,-0.19,1.719,,63.26,HHH,-0.962,0.100394,0.00307177,1.00053 kka2_1:8_T225I,kka2_1:8_225,Kka2,kka2_1:8,P00552,1.00053,NO,225,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.393,-3.64,1.247,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.100394,0.0113598,1.00053 kka2_1:8_T225I,kka2_1:8_225,Kka2,kka2_1:8,P00552,1.00053,NO,225,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.393,-3.64,1.247,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.100394,0.0113598,1.00053 beta-lactamase_156_E279K,beta-lactamase_156_279,TEM-1,beta-lactamase_156,P62593,1.00054,NO,279,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.111618,0.0192826,1.00054 beta-lactamase_2500_A268C,beta-lactamase_2500_268,TEM-1,beta-lactamase_2500,P62593,1.00054,NO,268,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.361275,0.0102525,1.00054 beta-lactamase_2500_A282Q,beta-lactamase_2500_282,TEM-1,beta-lactamase_2500,P62593,1.00054,NO,282,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.361275,0.0449821,1.00054 beta-lactamase_2500_D36E,beta-lactamase_2500_36,TEM-1,beta-lactamase_2500,P62593,1.00054,NO,36,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.732,-2.66,-0.072,,0.555,H,A,0.75,1.17,2.26,,77.62,AAP,-1.91167,0.361275,0.00476483,1.00054 beta-lactamase_625_L137S,beta-lactamase_625_137,TEM-1,beta-lactamase_625,P62593,1.00054,NO,137,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.03,-3.64,2.61,,,H,A,0.55,-0.38,1.5,,42.31,HHP,-1.58933,0.213352,0.00278599,1.00054 beta-lactamase_E166Q,beta-lactamase_166,TEM-1,beta-lactamase,P62593,1.00054,NO,166,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.756,-3.022,1.266,5.60527,0.508,G,A,0.52,1.05,2.124,,73.08,OAH,-1.42233,0.221079,0.00512989,1.00054 kka2_1:1_P98P,kka2_1:1_98,Kka2,kka2_1:1,P00552,1.00054,NO,98,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.526,-1.526,,,0.391,S,B,0.52,-0.65,1.521,,63.26,HOO,-1.19167,0.520039,0.00622754,1.00054 kka2_1:1_T72T,kka2_1:1_72,Kka2,kka2_1:1,P00552,1.00054,NO,72,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.38,-2.38,,,0.784,H,A,0.22,0.29,10.43,10.43,65.53,HPP,-2.238,0.520039,0.00750756,1.00054 kka2_1:2_F264F,kka2_1:2_264,Kka2,kka2_1:2,P00552,1.00054,NO,264,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.02,-1.02,,,0.296,.,?,0.58,0.02,2.303,,71.59,HHNA,-0.9655,0.295029,,1.00054 kka2_1:4_W91W,kka2_1:4_91,Kka2,kka2_1:4,P00552,1.00054,NO,91,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-1.178,-1.178,,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.168804,0.00358653,1.00054 kka2_1:8_L107L,kka2_1:8_107,Kka2,kka2_1:8,P00552,1.00054,NO,107,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.238,-1.238,,,0.197,.,B,0.55,-1.1,4.478,,71.59,BHH,-2.143,0.100394,0.00561937,1.00054 kka2_1:8_L107L,kka2_1:8_107,Kka2,kka2_1:8,P00552,1.00054,NO,107,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.238,-1.238,,,0.197,.,B,0.55,-1.1,4.478,,71.59,BHH,-2.143,0.100394,0.00561937,1.00054 kka2_1:8_L70L,kka2_1:8_70,Kka2,kka2_1:8,P00552,1.00054,NO,70,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.017,-1.017,,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.100394,0.00411884,1.00054 kka2_1:8_L70L,kka2_1:8_70,Kka2,kka2_1:8,P00552,1.00054,NO,70,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.017,-1.017,,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.100394,0.00411884,1.00054 kka2_1:8_P128R,kka2_1:8_128,Kka2,kka2_1:8,P00552,1.00054,NO,128,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.922,-4.235,2.313,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.100394,0.00774689,1.00054 kka2_1:8_P128R,kka2_1:8_128,Kka2,kka2_1:8,P00552,1.00054,NO,128,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.922,-4.235,2.313,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.100394,0.00774689,1.00054 beta-lactamase_0_D155C,beta-lactamase_0_155,TEM-1,beta-lactamase_0,P62593,1.00055,NO,155,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.889,-5.157,4.268,,0.049,,B,0.75,-0.9,16.833,16.833,64.69,OAB,-1.62267,0.0500837,0.00135315,1.00055 beta-lactamase_2500_A282V,beta-lactamase_2500_282,TEM-1,beta-lactamase_2500,P62593,1.00055,NO,282,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.361275,0.0449821,1.00055 beta-lactamase_39_S256A,beta-lactamase_39_256,TEM-1,beta-lactamase_39,P62593,1.00055,NO,256,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.0495842,0.00710634,1.00055 beta-lactamase_625_A230C,beta-lactamase_625_230,TEM-1,beta-lactamase_625,P62593,1.00055,NO,230,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.154,-4.695,3.541,,0.01,E,B,0.46,-1.17,0.777,,50,HHA,-1.079,0.213352,0.00516841,1.00055 beta-lactamase_625_G141R,beta-lactamase_625_141,TEM-1,beta-lactamase_625,P62593,1.00055,NO,141,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.828,-3.94,3.112,,0.575,T,l,0.29,-0.28,0.198,,64.69,HOO,-1.08933,0.213352,0.0012419,1.00055 kka2_1:1_A229A,kka2_1:1_229,Kka2,kka2_1:1,P00552,1.00055,NO,229,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.739,-1.739,,,0.32,H,A,0.46,-0.7,6.549,,63.64,HHA,-1.851,0.520039,0.00942138,1.00055 kka2_1:1_L232L,kka2_1:1_232,Kka2,kka2_1:1,P00552,1.00055,NO,232,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.514,-1.514,,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.520039,0.00800103,1.00055 kka2_1:1_N200N,kka2_1:1_200,Kka2,kka2_1:1,P00552,1.00055,NO,200,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-2.446,-2.446,,,0.756,T,L,0.61,-0.08,17.299,17.299,64.39,APO,-2.08,0.520039,0.00838549,1.00055 kka2_1:1_R140R,kka2_1:1_140,Kka2,kka2_1:1,P00552,1.00055,NO,140,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.351,-1.351,,,0.12,H,A,1.2,0.2,11.345,11.345,53.03,BBH,-1.885,0.520039,0.00430167,1.00055 kka2_1:1_R226R,kka2_1:1_226,Kka2,kka2_1:1,P00552,1.00055,NO,226,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.392,-1.392,,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.520039,0.0108032,1.00055 kka2_1:2_D159D,kka2_1:2_159,Kka2,kka2_1:2,P00552,1.00055,NO,159,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.82,-0.82,,,0.28,.,B,0.75,1.25,0.899,,48.11,HAA,-1.48333,0.295029,0.0030485,1.00055 kka2_1:2_L212L,kka2_1:2_212,Kka2,kka2_1:2,P00552,1.00055,NO,212,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.904,-0.904,,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.295029,0.0031426,1.00055 kka2_1:4_L184L,kka2_1:4_184,Kka2,kka2_1:4,P00552,1.00055,NO,184,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.496,-1.496,,,0.489,E,B,1.59,-0.06,4.495,,63.26,AHH,-1.24833,0.168804,0.00518742,1.00055 kka2_1:4_M116M,kka2_1:4_116,Kka2,kka2_1:4,P00552,1.00055,NO,116,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-2.482,-2.482,,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.168804,0.00745147,1.00055 kka2_1:4_Q219Q,kka2_1:4_219,Kka2,kka2_1:4,P00552,1.00055,NO,219,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-0.93,-0.93,,,0.088,H,A,0.64,-0.85,1.537,,50,HPA,-1.05167,0.168804,0.00237913,1.00055 kka2_1:4_Y244Y,kka2_1:4_244,Kka2,kka2_1:4,P00552,1.00055,NO,244,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-0.775,-0.775,,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.168804,0.00453187,1.00055 beta-lactamase_156_A133S,beta-lactamase_156_133,TEM-1,beta-lactamase_156,P62593,1.00056,NO,133,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.186,-3.092,1.906,,,H,A,0.46,-0.86,0.805,,67.83,HHP,-0.988333,0.111618,0.00468022,1.00056 beta-lactamase_39_D99L,beta-lactamase_39_99,TEM-1,beta-lactamase_39,P62593,1.00056,NO,99,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.191,-3.588,2.397,,0.402,G,A,0.75,0.36,0.374,,64.69,PAH,-1.794,0.0495842,0.00305446,1.00056 beta-lactamase_39_I261F,beta-lactamase_39_261,TEM-1,beta-lactamase_39,P62593,1.00056,NO,261,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.0495842,0.0123091,1.00056 beta-lactamase_39_P250H,beta-lactamase_39_250,TEM-1,beta-lactamase_39,P62593,1.00056,NO,250,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.0495842,0.00550899,1.00056 kka2_1:2_E262E,kka2_1:2_262,Kka2,kka2_1:2,P00552,1.00056,NO,262,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-0.829,-0.829,,,0.059,G,A,1.04,-0.18,2.383,,42.42,AAH,-0.816,0.295029,0.0191586,1.00056 kka2_1:2_P76P,kka2_1:2_76,Kka2,kka2_1:2,P00552,1.00056,NO,76,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.449,-1.449,,,0.331,.,B,0.52,-0.41,0.345,,63.64,HOO,-1.662,0.295029,0.00625685,1.00056 kka2_1:4_L107L,kka2_1:4_107,Kka2,kka2_1:4,P00552,1.00056,NO,107,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.238,-1.238,,,0.197,.,B,0.55,-1.1,0.398,,71.59,BHH,-2.143,0.168804,0.00561937,1.00056 kka2_1:4_V198V,kka2_1:4_198,Kka2,kka2_1:4,P00552,1.00056,NO,198,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.719,-1.719,,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.168804,0.00835002,1.00056 kka2_1:8_L126L,kka2_1:8_126,Kka2,kka2_1:8,P00552,1.00056,NO,126,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.246,-1.246,,,0.285,S,B,1.59,0.12,4.443,,51.89,PHA,-1.744,0.100394,0.0066485,1.00056 kka2_1:8_L126L,kka2_1:8_126,Kka2,kka2_1:8,P00552,1.00056,NO,126,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.246,-1.246,,,0.285,S,B,1.59,0.12,4.443,,51.89,PHA,-1.744,0.100394,0.0066485,1.00056 beta-lactamase_H94N,beta-lactamase_94,TEM-1,beta-lactamase,P62593,1.00057,NO,94,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-2.5,-3.811,1.311,6.1507,0.776,,B,0.63,1.24,1.176,,77.62,HBH,-1.872,0.221079,0.00389226,1.00057 beta-lactamase_T138M,beta-lactamase_138,TEM-1,beta-lactamase,P62593,1.00057,NO,138,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.506,-4.821,2.315,5.52585,0.662,H,A,0.3,-0.03,30.445,30.445,73.78,HPP,-1.81233,0.221079,0.00487868,1.00057 beta-lactamase_V8Q,beta-lactamase_8,TEM-1,beta-lactamase,P62593,1.00057,NO,8,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-2.358,-3.882,1.524,,,,,,,0.575,,77.62,BHH,-2.06267,0.221079,0.00226401,1.00057 kka2_1:1_G210G,kka2_1:1_210,Kka2,kka2_1:1,P00552,1.00057,NO,210,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.095,-1.095,,,0.103,T,A,0.29,-0.62,14.483,14.483,50,OOB,-0.966667,0.520039,0.00598378,1.00057 kka2_1:1_G99G,kka2_1:1_99,Kka2,kka2_1:1,P00552,1.00057,NO,99,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.596,-0.596,,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.520039,0.00186055,1.00057 kka2_1:2_I207I,kka2_1:2_207,Kka2,kka2_1:2,P00552,1.00057,NO,207,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.175,-1.175,,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.295029,0.00611824,1.00057 kka2_1:8_C192C,kka2_1:8_192,Kka2,kka2_1:8,P00552,1.00057,NO,192,C,C,CC,Special,Special,5.07,5.07,0,0,121,121,0,108.5,108.5,0,-1.067,-1.067,,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.100394,0.00485428,1.00057 kka2_1:8_C192C,kka2_1:8_192,Kka2,kka2_1:8,P00552,1.00057,NO,192,C,C,CC,Special,Special,5.07,5.07,0,0,121,121,0,108.5,108.5,0,-1.067,-1.067,,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.100394,0.00485428,1.00057 kka2_1:8_F171F,kka2_1:8_171,Kka2,kka2_1:8,P00552,1.00057,NO,171,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.326,-1.326,,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.100394,0.00821426,1.00057 kka2_1:8_F171F,kka2_1:8_171,Kka2,kka2_1:8,P00552,1.00057,NO,171,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.326,-1.326,,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.100394,0.00821426,1.00057 Pab1_Q194Y,Pab1_194,Pab1,Pab1,P04147,1.00057,NO,194,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.179,-3.879,1.7,,,,,,,,,,OPA,-1.59767,0.175299,0.0016145,1.00057 beta-lactamase_156_G194A,beta-lactamase_156_194,TEM-1,beta-lactamase_156,P62593,1.00058,NO,194,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.396,-2.558,1.162,,0.276,S,b,0.29,0.36,1.346,,67.83,POA,-1.832,0.111618,0.00392163,1.00058 beta-lactamase_156_H110C,beta-lactamase_156_110,TEM-1,beta-lactamase_156,P62593,1.00058,NO,110,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-1.706,-5.217,3.511,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.111618,0.00441499,1.00058 beta-lactamase_156_P105V,beta-lactamase_156_105,TEM-1,beta-lactamase_156,P62593,1.00058,NO,105,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.813,-3.554,2.741,,0.226,T,A,0.52,0.8,1.154,,63.29,POH,-1.01533,0.111618,0.0011981,1.00058 beta-lactamase_2500_V106I,beta-lactamase_2500_106,TEM-1,beta-lactamase_2500,P62593,1.00058,NO,106,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.218,-2.124,0.906,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.361275,0.00304168,1.00058 beta-lactamase_39_Q86S,beta-lactamase_39_86,TEM-1,beta-lactamase_39,P62593,1.00058,NO,86,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.4,-2.711,0.311,,0.696,S,A,0.64,2.38,27.704,27.704,77.62,OPA,-1.61067,0.0495842,0.00450027,1.00058 kka2_1:1_G233G,kka2_1:1_233,Kka2,kka2_1:1,P00552,1.00058,NO,233,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.748,-0.748,,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.520039,0.00232366,1.00058 kka2_1:2_F206F,kka2_1:2_206,Kka2,kka2_1:2,P00552,1.00058,NO,206,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.349,-1.349,,,0.006,E,B,0.58,-1.21,0.978,,63.64,OHH,-1.04,0.295029,0.00936868,1.00058 kka2_1:2_V97V,kka2_1:2_97,Kka2,kka2_1:2,P00552,1.00058,NO,97,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.453,-1.453,,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.295029,0.00737869,1.00058 kka2_1:4_L94L,kka2_1:4_94,Kka2,kka2_1:4,P00552,1.00058,NO,94,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.618,-1.618,,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.168804,0.00520888,1.00058 Pab1_A178S,Pab1_178,Pab1,Pab1,P04147,1.00058,NO,178,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.579,-2.038,0.459,,0.019,H,A,0.64,0.64,2.7,,81.63,OHH,-1.61067,0.175299,0.00160192,1.00058 beta-lactamase_156_G85Y,beta-lactamase_156_85,TEM-1,beta-lactamase_156,P62593,1.00059,NO,85,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.011,-4.409,3.398,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.111618,0.00252173,1.00059 beta-lactamase_625_A247G,beta-lactamase_625_247,TEM-1,beta-lactamase_625,P62593,1.00059,NO,247,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.213352,0.00611275,1.00059 beta-lactamase_625_R239A,beta-lactamase_625_239,TEM-1,beta-lactamase_625,P62593,1.00059,NO,239,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.213352,0.00213852,1.00059 kka2_1:1_Q219Q,kka2_1:1_219,Kka2,kka2_1:1,P00552,1.00059,NO,219,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-0.93,-0.93,,,0.088,H,A,0.4,-0.85,1.917,,50,HPA,-1.05167,0.520039,0.00237913,1.00059 kka2_1:2_F240F,kka2_1:2_240,Kka2,kka2_1:2,P00552,1.00059,NO,240,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-0.911,-0.911,,,,H,A,0.58,-1.21,0.373,,50.38,BHH,-1.67267,0.295029,0.00552543,1.00059 kka2_1:2_L193L,kka2_1:2_193,Kka2,kka2_1:2,P00552,1.00059,NO,193,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.983,-0.983,,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.295029,0.00480179,1.00059 kka2_1:2_L260L,kka2_1:2_260,Kka2,kka2_1:2,P00552,1.00059,NO,260,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.741,-0.741,,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.295029,0.0233782,1.00059 kka2_1:4_E63E,kka2_1:4_63,Kka2,kka2_1:4,P00552,1.00059,NO,63,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-0.762,-0.762,,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.168804,0.00118399,1.00059 kka2_1:4_H162H,kka2_1:4_162,Kka2,kka2_1:4,P00552,1.00059,NO,162,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-2.319,-2.319,,,0.071,G,A,0.17,1.01,3.187,,64.39,ABP,-2.02067,0.168804,0.00616145,1.00059 kka2_1:4_V97V,kka2_1:4_97,Kka2,kka2_1:4,P00552,1.00059,NO,97,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.453,-1.453,,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.168804,0.00737869,1.00059 kka2_1:8_H162H,kka2_1:8_162,Kka2,kka2_1:8,P00552,1.00059,NO,162,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-2.319,-2.319,,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.100394,0.00616145,1.00059 kka2_1:8_H162H,kka2_1:8_162,Kka2,kka2_1:8,P00552,1.00059,NO,162,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-2.319,-2.319,,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.100394,0.00616145,1.00059 kka2_1:8_P109P,kka2_1:8_109,Kka2,kka2_1:8,P00552,1.00059,NO,109,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.412,-1.412,,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.100394,0.0070929,1.00059 kka2_1:8_P109P,kka2_1:8_109,Kka2,kka2_1:8,P00552,1.00059,NO,109,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.412,-1.412,,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.100394,0.0070929,1.00059 beta-lactamase_2500_D252C,beta-lactamase_2500_252,TEM-1,beta-lactamase_2500,P62593,1.0006,NO,252,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.94,,,,0.766,,B,1.59,1.16,,,67.83,OAO,-2.0965,0.361275,0.00575769,1.0006 beta-lactamase_39_L188W,beta-lactamase_39_188,TEM-1,beta-lactamase_39,P62593,1.0006,NO,188,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.166,-3.108,1.942,,,H,A,0.55,-0.3,2.982,,60.14,PHB,-1.47033,0.0495842,0.00295687,1.0006 beta-lactamase_625_A170Q,beta-lactamase_625_170,TEM-1,beta-lactamase_625,P62593,1.0006,NO,170,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.237,-4.086,2.849,,0.126,,L,0.46,-0.35,3.626,,64.69,AHH,-1.63267,0.213352,0.00431903,1.0006 beta-lactamase_625_L55F,beta-lactamase_625_55,TEM-1,beta-lactamase_625,P62593,1.0006,NO,55,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.86,-2.527,0.667,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.213352,0.00403741,1.0006 kka2_1:1_D118D,kka2_1:1_118,Kka2,kka2_1:1,P00552,1.0006,NO,118,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.07,-2.07,,,0.61,H,A,0.75,-0.05,13.434,13.434,64.39,HAH,-1.32367,0.520039,0.0067852,1.0006 kka2_1:2_I196I,kka2_1:2_196,Kka2,kka2_1:2,P00552,1.0006,NO,196,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-2.115,-2.115,,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.295029,0.0107273,1.0006 beta-lactamase_39_Q204S,beta-lactamase_39_204,TEM-1,beta-lactamase_39,P62593,1.00061,NO,204,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-1.382,-3.344,1.962,,0.204,H,A,0.64,0.09,0.489,,66.08,PPH,-1.49067,0.0495842,0.00364106,1.00061 kka2_1:1_L241L,kka2_1:1_241,Kka2,kka2_1:1,P00552,1.00061,NO,241,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.158,-1.158,,,0.08,H,A,0.55,-0.82,1.685,,63.26,HHH,-1.58533,0.520039,0.0117299,1.00061 kka2_1:2_D183D,kka2_1:2_183,Kka2,kka2_1:2,P00552,1.00061,NO,183,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.204,-1.204,,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.295029,0.00426304,1.00061 kka2_1:4_G201G,kka2_1:4_201,Kka2,kka2_1:4,P00552,1.00061,NO,201,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.56,-1.56,,,0.149,T,l,0.29,-0.57,0.284,,52.65,POB,-1.92233,0.168804,0.00820117,1.00061 kka2_1:8_A34A,kka2_1:8_34,Kka2,kka2_1:8,P00552,1.00061,NO,34,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.928,-0.928,,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.100394,0.00343484,1.00061 kka2_1:8_A34A,kka2_1:8_34,Kka2,kka2_1:8,P00552,1.00061,NO,34,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.928,-0.928,,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.100394,0.00343484,1.00061 kka2_1:8_C209C,kka2_1:8_209,Kka2,kka2_1:8,P00552,1.00061,NO,209,C,C,CC,Special,Special,5.07,5.07,0,0,121,121,0,108.5,108.5,0,-0.906,-0.906,,,,,a,1.5,-0.89,0.391,,19.32,AOO,-0.903,0.100394,0.00260862,1.00061 kka2_1:8_C209C,kka2_1:8_209,Kka2,kka2_1:8,P00552,1.00061,NO,209,C,C,CC,Special,Special,5.07,5.07,0,0,121,121,0,108.5,108.5,0,-0.906,-0.906,,,,,a,1.5,-0.89,0.391,,19.32,AOO,-0.903,0.100394,0.00260862,1.00061 beta-lactamase_2500_K109T,beta-lactamase_2500_109,TEM-1,beta-lactamase_2500,P62593,1.00062,NO,109,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.734,-2.559,0.825,,0.787,G,A,2.34,2.21,0.998,,72.73,ABB,-1.63333,0.361275,0.00462493,1.00062 beta-lactamase_39_L111N,beta-lactamase_39_111,TEM-1,beta-lactamase_39,P62593,1.00062,NO,111,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.76,-4.132,2.372,,0.328,T,A,0.55,0.93,4.334,,64.34,BHP,-1.884,0.0495842,0.00480671,1.00062 beta-lactamase_625_L192T,beta-lactamase_625_192,TEM-1,beta-lactamase_625,P62593,1.00062,NO,192,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.254,-3.48,2.226,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.213352,0.00558728,1.00062 kka2_1:1_V185V,kka2_1:1_185,Kka2,kka2_1:1,P00552,1.00062,NO,185,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.045,-1.045,,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.520039,0.00367031,1.00062 kka2_1:2_C131C,kka2_1:2_131,Kka2,kka2_1:2,P00552,1.00062,NO,131,C,C,CC,Special,Special,5.07,5.07,0,0,121,121,0,108.5,108.5,0,-0.831,-0.831,,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.295029,0.00170814,1.00062 kka2_1:2_G245G,kka2_1:2_245,Kka2,kka2_1:2,P00552,1.00062,NO,245,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.812,-0.812,,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.295029,0.00683899,1.00062 kka2_1:2_M197M,kka2_1:2_197,Kka2,kka2_1:2,P00552,1.00062,NO,197,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.707,-1.707,,,0.121,E,B,0.55,-1.19,2.097,,65.53,HHH,-1.847,0.295029,0.00921295,1.00062 kka2_1:4_P132P,kka2_1:4_132,Kka2,kka2_1:4,P00552,1.00062,NO,132,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.775,-0.775,,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.168804,0.0018489,1.00062 PSD95pdz3_P346K,PSD95pdz3_346,PSD95pdz3,PSD95pdz3,P31016,1.00062,NO,346,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.236,-3.139,1.903,5.02406,,,,,14.6629,,,,OOH,-1.18367,0.0758425,0.000758563,1.00062 beta-lactamase_156_Q88S,beta-lactamase_156_88,TEM-1,beta-lactamase_156,P62593,1.00063,NO,88,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.086,-2.48,0.394,,0.807,,B,0.64,2.03,0.911,,77.62,APH,-1.53433,0.111618,0.00504167,1.00063 beta-lactamase_2500_E195R,beta-lactamase_2500_195,TEM-1,beta-lactamase_2500,P62593,1.00063,NO,195,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.186,-3.074,0.888,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.361275,0.00496565,1.00063 beta-lactamase_39_R41A,beta-lactamase_39_41,TEM-1,beta-lactamase_39,P62593,1.00063,NO,41,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-0.942,-3.041,2.099,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.0495842,0.00123327,1.00063 beta-lactamase_39_S80V,beta-lactamase_39_80,TEM-1,beta-lactamase_39,P62593,1.00063,NO,80,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.029,-2.695,0.666,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.0495842,0.00565569,1.00063 beta-lactamase_625_N173D,beta-lactamase_625_173,TEM-1,beta-lactamase_625,P62593,1.00063,NO,173,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-2.663,-2.368,-0.295,,1.044,T,l,0.61,1.25,1.426,,77.62,OPA,-1.46633,0.213352,0.0033769,1.00063 kka2_1:1_D190D,kka2_1:1_190,Kka2,kka2_1:1,P00552,1.00063,NO,190,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.708,-0.708,,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.520039,0.00247989,1.00063 kka2_1:1_G164G,kka2_1:1_164,Kka2,kka2_1:1,P00552,1.00063,NO,164,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.869,-0.869,,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.520039,0.00442091,1.00063 kka2_1:1_G95G,kka2_1:1_95,Kka2,kka2_1:1,P00552,1.00063,NO,95,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-2.403,-2.403,,,0.126,E,B,0.29,-0.74,7.822,,71.59,HOA,-2.198,0.520039,0.00743616,1.00063 kka2_1:2_P109P,kka2_1:2_109,Kka2,kka2_1:2,P00552,1.00063,NO,109,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.412,-1.412,,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.295029,0.0070929,1.00063 kka2_1:4_A224V,kka2_1:4_224,Kka2,kka2_1:4,P00552,1.00063,NO,224,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.977,-2.571,1.594,,,H,A,0.46,-1.26,0.93,,63.64,HHP,-1.41033,0.168804,0.00352047,1.00063 beta-lactamase_156_G39E,beta-lactamase_156_39,TEM-1,beta-lactamase_156,P62593,1.00064,NO,39,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.864,-2.833,0.969,,0.701,T,L,0.29,0.47,1.454,,77.62,HOH,-1.53633,0.111618,0.00487611,1.00064 beta-lactamase_2500_E145M,beta-lactamase_2500_145,TEM-1,beta-lactamase_2500,P62593,1.00064,NO,145,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.357,-4.807,2.45,,0.545,H,A,1.04,0.79,2.124,,77.62,BAH,-2.069,0.361275,0.00553285,1.00064 beta-lactamase_2500_Q97E,beta-lactamase_2500_97,TEM-1,beta-lactamase_2500,P62593,1.00064,NO,97,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.072,-2.167,0.095,,0.823,G,A,0.64,2.42,1.157,,77.62,PPP,-2.43833,0.361275,0.0045116,1.00064 beta-lactamase_625_E102S,beta-lactamase_625_102,TEM-1,beta-lactamase_625,P62593,1.00064,NO,102,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.118,-2.129,0.011,,0.722,S,B,1.04,1.82,1.336,,73.08,HAH,-1.581,0.213352,0.00486633,1.00064 beta-lactamase_625_E119K,beta-lactamase_625_119,TEM-1,beta-lactamase_625,P62593,1.00064,NO,119,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.412,-3.343,1.931,,0.358,H,A,1.04,0.51,1.034,,63.99,BAH,-1.623,0.213352,0.00386966,1.00064 beta-lactamase_A34S,beta-lactamase_34,TEM-1,beta-lactamase,P62593,1.00064,NO,34,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.059,-2.213,0.154,4.9129,,H,A,0.75,-0.54,3.614,,73.78,AHA,-1.74967,0.221079,0.00407913,1.00064 beta-lactamase_R118Q,beta-lactamase_118,TEM-1,beta-lactamase,P62593,1.00064,NO,118,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.413,-3.932,1.519,5.8227,0.457,H,A,0.68,1.39,2.144,,77.62,HBA,-1.785,0.221079,0.00538794,1.00064 gb1_T242R,gb1_242,gb1,gb1,P06654,1.00064,NO,242,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.245,-3.443,2.198,,,,,,,,,,APP,-1.444,0.177985,0.00243886,1.00064 gb1_T279A,gb1_279,gb1,gb1,P06654,1.00064,NO,279,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.32,-2.752,1.432,,,,,,,0.529,,35.71,HPH,-1.50067,0.177985,0.00421454,1.00064 kka2_1:1_A119A,kka2_1:1_119,Kka2,kka2_1:1,P00552,1.00064,NO,119,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.073,-1.073,,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.520039,0.00441074,1.00064 kka2_1:2_A237A,kka2_1:2_237,Kka2,kka2_1:2,P00552,1.00064,NO,237,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.12,-2.12,,,0.068,H,A,0.46,-0.71,2.369,,92.05,HHA,-2.10433,0.295029,0.012257,1.00064 kka2_1:2_G201G,kka2_1:2_201,Kka2,kka2_1:2,P00552,1.00064,NO,201,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.56,-1.56,,,0.149,T,l,0.29,-0.57,16.092,16.092,52.65,POB,-1.92233,0.295029,0.00820117,1.00064 kka2_1:2_I115I,kka2_1:2_115,Kka2,kka2_1:2,P00552,1.00064,NO,115,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.606,-1.606,,,0.105,H,A,0.48,-1.18,0.878,,65.53,PHH,-2.205,0.295029,0.00836567,1.00064 kka2_1:2_P194P,kka2_1:2_194,Kka2,kka2_1:2,P00552,1.00064,NO,194,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.846,-0.846,,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.295029,0.00314194,1.00064 kka2_1:4_R140R,kka2_1:4_140,Kka2,kka2_1:4,P00552,1.00064,NO,140,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.351,-1.351,,,0.12,H,A,1.2,0.2,2.561,,53.03,BBH,-1.885,0.168804,0.00430167,1.00064 kka2_1:4_W69W,kka2_1:4_69,Kka2,kka2_1:4,P00552,1.00064,NO,69,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-0.859,-0.859,,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.168804,0.0012874,1.00064 kka2_1:8_H135H,kka2_1:8_135,Kka2,kka2_1:8,P00552,1.00064,NO,135,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-1.331,-1.331,,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.100394,0.00532566,1.00064 kka2_1:8_H135H,kka2_1:8_135,Kka2,kka2_1:8,P00552,1.00064,NO,135,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-1.331,-1.331,,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.100394,0.00532566,1.00064 kka2_1:8_K112K,kka2_1:8_112,Kka2,kka2_1:8,P00552,1.00064,NO,112,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-2.491,-2.491,,,0.076,H,A,1.3,-1.37,10.58,10.58,56.06,ABH,-2.00133,0.100394,0.00645389,1.00064 kka2_1:8_K112K,kka2_1:8_112,Kka2,kka2_1:8,P00552,1.00064,NO,112,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-2.491,-2.491,,,0.076,H,A,1.3,-1.37,10.58,10.58,56.06,ABH,-2.00133,0.100394,0.00645389,1.00064 kka2_1:8_T73G,kka2_1:8_73,Kka2,kka2_1:8,P00552,1.00064,NO,73,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.51,-3.619,1.109,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.100394,0.00628605,1.00064 kka2_1:8_T73G,kka2_1:8_73,Kka2,kka2_1:8,P00552,1.00064,NO,73,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.51,-3.619,1.109,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.100394,0.00628605,1.00064 kka2_1:8_V214V,kka2_1:8_214,Kka2,kka2_1:8,P00552,1.00064,NO,214,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.261,-1.261,,,0.117,E,B,1.48,-0.31,1.859,,64.39,OHH,-0.941667,0.100394,0.00692782,1.00064 kka2_1:8_V214V,kka2_1:8_214,Kka2,kka2_1:8,P00552,1.00064,NO,214,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.261,-1.261,,,0.117,E,B,1.48,-0.31,1.859,,64.39,OHH,-0.941667,0.100394,0.00692782,1.00064 beta-lactamase_156_L47I,beta-lactamase_156_47,TEM-1,beta-lactamase_156,P62593,1.00065,NO,47,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.876,-2.384,0.508,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.111618,0.00439844,1.00065 beta-lactamase_39_L150Y,beta-lactamase_39_150,TEM-1,beta-lactamase_39,P62593,1.00065,NO,150,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.326,-4.133,2.807,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.0495842,0.00463171,1.00065 beta-lactamase_625_A230S,beta-lactamase_625_230,TEM-1,beta-lactamase_625,P62593,1.00065,NO,230,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.154,-2.48,1.326,,0.01,E,B,0.46,-1.17,0.777,,50,HHA,-1.079,0.213352,0.00516841,1.00065 kka2_1:4_P109P,kka2_1:4_109,Kka2,kka2_1:4,P00552,1.00065,NO,109,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.412,-1.412,,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.168804,0.0070929,1.00065 beta-lactamase_156_E145P,beta-lactamase_156_145,TEM-1,beta-lactamase_156,P62593,1.00066,NO,145,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.357,-3.914,1.557,,0.545,H,A,1.04,0.79,3.661,,77.62,BAH,-2.069,0.111618,0.00553285,1.00066 beta-lactamase_156_K109C,beta-lactamase_156_109,TEM-1,beta-lactamase_156,P62593,1.00066,NO,109,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.734,-5.237,3.503,,0.787,G,A,2.34,2.21,6.031,,72.73,ABB,-1.63333,0.111618,0.00462493,1.00066 beta-lactamase_39_L100H,beta-lactamase_39_100,TEM-1,beta-lactamase_39,P62593,1.00066,NO,100,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.218,-4.855,3.637,,0.343,,B,0.55,0.13,8.311,,63.29,AHH,-1.23467,0.0495842,0.00413885,1.00066 kka2_1:2_L223L,kka2_1:2_223,Kka2,kka2_1:2,P00552,1.00066,NO,223,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.861,-0.861,,,,H,A,0.55,-1.24,0.266,,50,HHH,-0.854333,0.295029,0.00253574,1.00066 kka2_1:2_P132P,kka2_1:2_132,Kka2,kka2_1:2,P00552,1.00066,NO,132,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.775,-0.775,,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.295029,0.0018489,1.00066 kka2_1:4_C192C,kka2_1:4_192,Kka2,kka2_1:4,P00552,1.00066,NO,192,C,C,CC,Special,Special,5.07,5.07,0,0,121,121,0,108.5,108.5,0,-1.067,-1.067,,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.168804,0.00485428,1.00066 kka2_1:4_F48F,kka2_1:4_48,Kka2,kka2_1:4,P00552,1.00066,NO,48,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.453,-1.453,,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.168804,0.00475422,1.00066 kka2_1:8_F256F,kka2_1:8_256,Kka2,kka2_1:8,P00552,1.00066,NO,256,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.49,-1.49,,,,H,A,1.62,-0.78,1.713,,53.03,HHH,-1.423,0.100394,0.0132841,1.00066 kka2_1:8_F256F,kka2_1:8_256,Kka2,kka2_1:8,P00552,1.00066,NO,256,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.49,-1.49,,,,H,A,1.62,-0.78,1.713,,53.03,HHH,-1.423,0.100394,0.0132841,1.00066 kka2_1:8_L212L,kka2_1:8_212,Kka2,kka2_1:8,P00552,1.00066,NO,212,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.904,-0.904,,,,,B,1.59,-0.78,1.708,,42.42,BHO,-0.799667,0.100394,0.0031426,1.00066 kka2_1:8_L212L,kka2_1:8_212,Kka2,kka2_1:8,P00552,1.00066,NO,212,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.904,-0.904,,,,,B,1.59,-0.78,1.708,,42.42,BHO,-0.799667,0.100394,0.0031426,1.00066 kka2_1:8_M116M,kka2_1:8_116,Kka2,kka2_1:8,P00552,1.00066,NO,116,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-2.482,-2.482,,,,H,A,1.59,-0.88,4.659,,71.59,HHH,-1.63867,0.100394,0.00745147,1.00066 kka2_1:8_M116M,kka2_1:8_116,Kka2,kka2_1:8,P00552,1.00066,NO,116,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-2.482,-2.482,,,,H,A,1.59,-0.88,4.659,,71.59,HHH,-1.63867,0.100394,0.00745147,1.00066 beta-lactamase_156_A200P,beta-lactamase_156_200,TEM-1,beta-lactamase_156,P62593,1.00067,NO,200,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.878,-2.581,0.703,,0.757,H,A,0.46,-0.19,16.368,16.368,77.62,HHP,-2.001,0.111618,0.0060056,1.00067 beta-lactamase_156_V214Y,beta-lactamase_156_214,TEM-1,beta-lactamase_156,P62593,1.00067,NO,214,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.299,-4.125,2.826,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.111618,0.00628442,1.00067 kka2_1:2_L174L,kka2_1:2_174,Kka2,kka2_1:2,P00552,1.00067,NO,174,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.952,-0.952,,,,H,A,1.59,-0.31,8.521,,51.89,BHB,-2.08533,0.295029,0.00438501,1.00067 kka2_1:2_L259L,kka2_1:2_259,Kka2,kka2_1:2,P00552,1.00067,NO,259,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.088,-1.088,,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.295029,0.0206964,1.00067 kka2_1:2_Q219Q,kka2_1:2_219,Kka2,kka2_1:2,P00552,1.00067,NO,219,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-0.93,-0.93,,,0.088,H,A,0.4,-0.85,1.917,,50,HPA,-1.05167,0.295029,0.00237913,1.00067 kka2_1:2_Y257Y,kka2_1:2_257,Kka2,kka2_1:2,P00552,1.00067,NO,257,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-1.064,-1.064,,,0.022,H,A,0.21,-0.88,0.833,,52.65,HHB,-1.39333,0.295029,0.0148191,1.00067 kka2_1:4_H124H,kka2_1:4_124,Kka2,kka2_1:4,P00552,1.00067,NO,124,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-0.84,-0.84,,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.168804,0.00211296,1.00067 kka2_1:8_L94L,kka2_1:8_94,Kka2,kka2_1:8,P00552,1.00067,NO,94,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.618,-1.618,,,0.058,E,B,1.59,-0.52,2.197,,56.06,HHO,-1.612,0.100394,0.00520888,1.00067 kka2_1:8_L94L,kka2_1:8_94,Kka2,kka2_1:8,P00552,1.00067,NO,94,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.618,-1.618,,,0.058,E,B,1.59,-0.52,2.197,,56.06,HHO,-1.612,0.100394,0.00520888,1.00067 kka2_1:8_P194P,kka2_1:8_194,Kka2,kka2_1:8,P00552,1.00067,NO,194,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.846,-0.846,,,0.308,G,A,0.52,-1.19,4.861,,53.03,HOP,-0.888333,0.100394,0.00314194,1.00067 kka2_1:8_P194P,kka2_1:8_194,Kka2,kka2_1:8,P00552,1.00067,NO,194,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.846,-0.846,,,0.308,G,A,0.52,-1.19,4.861,,53.03,HOP,-0.888333,0.100394,0.00314194,1.00067 beta-lactamase_156_D231S,beta-lactamase_156_231,TEM-1,beta-lactamase_156,P62593,1.00068,NO,231,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.816,-3.186,2.37,,,E,B,0.75,-1.06,2.66,,65.38,HAB,-0.994,0.111618,0.00107395,1.00068 kka2_1:1_T187T,kka2_1:1_187,Kka2,kka2_1:1,P00552,1.00068,NO,187,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.273,-1.273,,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.520039,0.00693073,1.00068 kka2_1:2_A215A,kka2_1:2_215,Kka2,kka2_1:2,P00552,1.00068,NO,215,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.968,-0.968,,,0.039,E,B,0.46,-0.59,2.137,,50.38,HHA,-1.00467,0.295029,0.00529129,1.00068 kka2_1:4_L259L,kka2_1:4_259,Kka2,kka2_1:4,P00552,1.00068,NO,259,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.088,-1.088,,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.168804,0.0206964,1.00068 beta-lactamase_0_R275M,beta-lactamase_0_275,TEM-1,beta-lactamase_0,P62593,1.00069,NO,275,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.0500837,0.0141984,1.00069 beta-lactamase_156_S283V,beta-lactamase_156_283,TEM-1,beta-lactamase_156,P62593,1.00069,NO,283,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.111618,0.0429138,1.00069 beta-lactamase_156_T264H,beta-lactamase_156_264,TEM-1,beta-lactamase_156,P62593,1.00069,NO,264,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.111618,0.0119399,1.00069 kka2_1:1_G213G,kka2_1:1_213,Kka2,kka2_1:1,P00552,1.00069,NO,213,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.596,-0.596,,,,E,b,0.29,-0.4,,,,HOH,-0.920333,0.520039,0.00187654,1.00069 kka2_1:4_K112K,kka2_1:4_112,Kka2,kka2_1:4,P00552,1.00069,NO,112,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-2.491,-2.491,,,0.076,H,A,2.34,-1.37,0.39,,56.06,ABH,-2.00133,0.168804,0.00645389,1.00069 kka2_1:8_E59E,kka2_1:8_59,Kka2,kka2_1:8,P00552,1.00069,NO,59,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-0.952,-0.952,,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.100394,0.00280355,1.00069 kka2_1:8_E59E,kka2_1:8_59,Kka2,kka2_1:8,P00552,1.00069,NO,59,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-0.952,-0.952,,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.100394,0.00280355,1.00069 kka2_1:8_G245G,kka2_1:8_245,Kka2,kka2_1:8,P00552,1.00069,NO,245,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.812,-0.812,,,0.655,T,g,0.75,0.03,1.148,,65.53,HOH,-1.19833,0.100394,0.00683899,1.00069 kka2_1:8_G245G,kka2_1:8_245,Kka2,kka2_1:8,P00552,1.00069,NO,245,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.812,-0.812,,,0.655,T,g,0.75,0.03,1.148,,65.53,HOH,-1.19833,0.100394,0.00683899,1.00069 PSD95pdz3_I377D,PSD95pdz3_377,PSD95pdz3,PSD95pdz3,P31016,1.00069,NO,377,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.873,-3.796,1.923,4.9532,,,,,19.185,2.364,,87.71,HHH,-1.49567,0.0758425,0.000795475,1.00069 beta-lactamase_0_V157N,beta-lactamase_0_157,TEM-1,beta-lactamase_0,P62593,1.0007,NO,157,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.751,-3.925,2.174,,0.308,S,a,0.44,-0.75,3.106,,69.58,BHP,-2.00767,0.0500837,0.00506849,1.0007 beta-lactamase_39_T116M,beta-lactamase_39_116,TEM-1,beta-lactamase_39,P62593,1.0007,NO,116,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.28,-4.634,3.354,,0.115,E,B,0.22,-0.12,1.133,,67.48,HPH,-1.39967,0.0495842,0.00336175,1.0007 kka2_1:2_A117A,kka2_1:2_117,Kka2,kka2_1:2,P00552,1.0007,NO,117,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.828,-0.828,,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.295029,0.00282984,1.0007 kka2_1:2_H135H,kka2_1:2_135,Kka2,kka2_1:2,P00552,1.0007,NO,135,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-1.331,-1.331,,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.295029,0.00532566,1.0007 beta-lactamase_625_D161N,beta-lactamase_625_161,TEM-1,beta-lactamase_625,P62593,1.00071,NO,161,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.891,-3.293,2.402,,0.341,,A,0.75,-0.52,4.655,,61.19,HAB,-0.961333,0.213352,0.000897697,1.00071 beta-lactamase_625_E210F,beta-lactamase_625_210,TEM-1,beta-lactamase_625,P62593,1.00071,NO,210,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.319,-4.128,1.809,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.213352,0.00663582,1.00071 beta-lactamase_625_R118G,beta-lactamase_625_118,TEM-1,beta-lactamase_625,P62593,1.00071,NO,118,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.413,-1.757,-0.656,,0.457,H,A,1.2,1.39,2.144,,77.62,HBA,-1.785,0.213352,0.00538794,1.00071 beta-lactamase_D269Y,beta-lactamase_269,TEM-1,beta-lactamase,P62593,1.00071,NO,269,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.156,-4.399,2.243,5.47645,0.646,H,A,0.23,0.4,21.796,21.796,77.62,HAA,-1.96733,0.221079,0.00950944,1.00071 beta-lactamase_E270M,beta-lactamase_270,TEM-1,beta-lactamase,P62593,1.00071,NO,270,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.723,-4.709,2.986,5.33196,0.422,H,A,0.52,1.15,1.745,,64.34,AAB,-1.70933,0.221079,0.00767762,1.00071 kka2_1:2_D261D,kka2_1:2_261,Kka2,kka2_1:2,P00552,1.00071,NO,261,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.708,-0.708,,,0.146,G,A,0.75,-0.33,,,,HAA,-0.759333,0.295029,0.0224846,1.00071 kka2_1:2_R258R,kka2_1:2_258,Kka2,kka2_1:2,P00552,1.00071,NO,258,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.626,-1.626,,,0.316,H,A,1.2,-0.85,7.485,7.485,53.03,HBH,-1.25933,0.295029,0.00983174,1.00071 kka2_1:4_I221I,kka2_1:4_221,Kka2,kka2_1:4,P00552,1.00071,NO,221,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.739,-1.739,,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.168804,0.00945908,1.00071 kka2_1:8_E63E,kka2_1:8_63,Kka2,kka2_1:8,P00552,1.00071,NO,63,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-0.762,-0.762,,,0.043,H,A,1.52,-0.43,,,,AAH,-1.283,0.100394,0.00118399,1.00071 kka2_1:8_E63E,kka2_1:8_63,Kka2,kka2_1:8,P00552,1.00071,NO,63,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-0.762,-0.762,,,0.043,H,A,1.52,-0.43,,,,AAH,-1.283,0.100394,0.00118399,1.00071 beta-lactamase_39_A133C,beta-lactamase_39_133,TEM-1,beta-lactamase_39,P62593,1.00072,NO,133,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.186,-4.706,3.52,,,H,A,0.46,-0.86,0.373,,67.83,HHP,-0.988333,0.0495842,0.00468022,1.00072 beta-lactamase_39_S104G,beta-lactamase_39_104,TEM-1,beta-lactamase_39,P62593,1.00072,NO,104,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.015,-3.017,2.002,,0.04,,b,0.27,0.57,4.02,,63.29,HPO,-1.05267,0.0495842,0.00218083,1.00072 beta-lactamase_625_G216R,beta-lactamase_625_216,TEM-1,beta-lactamase_625,P62593,1.00072,NO,216,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.477,-2.93,1.453,,0.437,I,A,0.29,-0.58,1.718,,74.48,HOO,-1.68067,0.213352,0.00639568,1.00072 beta-lactamase_625_L196S,beta-lactamase_625_196,TEM-1,beta-lactamase_625,P62593,1.00072,NO,196,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-2.478,-2.752,0.274,,0.518,S,A,0.55,1.35,12.152,12.152,77.62,AHH,-1.839,0.213352,0.00512144,1.00072 beta-lactamase_625_M270H,beta-lactamase_625_270,TEM-1,beta-lactamase_625,P62593,1.00072,NO,270,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.213352,0.00767762,1.00072 beta-lactamase_625_R176S,beta-lactamase_625_176,TEM-1,beta-lactamase_625,P62593,1.00072,NO,176,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-0.863,-3.386,2.523,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.213352,0.00105554,1.00072 kka2_1:1_G189G,kka2_1:1_189,Kka2,kka2_1:1,P00552,1.00072,NO,189,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.596,-0.596,,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.520039,0.00253688,1.00072 kka2_1:2_F203F,kka2_1:2_203,Kka2,kka2_1:2,P00552,1.00072,NO,203,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-0.911,-0.911,,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.295029,0.00318738,1.00072 kka2_1:2_G181C,kka2_1:2_181,Kka2,kka2_1:2,P00552,1.00072,NO,181,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-2.698,-5.203,2.505,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.295029,0.00728319,1.00072 kka2_1:4_S32S,kka2_1:4_32,Kka2,kka2_1:4,P00552,1.00072,NO,32,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-0.804,-0.804,,,0.768,S,b,0.27,3.75,,,,OPA,-1.74533,0.168804,0.00149998,1.00072 kka2_1:8_I196I,kka2_1:8_196,Kka2,kka2_1:8,P00552,1.00072,NO,196,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-2.115,-2.115,,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.100394,0.0107273,1.00072 kka2_1:8_I196I,kka2_1:8_196,Kka2,kka2_1:8,P00552,1.00072,NO,196,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-2.115,-2.115,,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.100394,0.0107273,1.00072 beta-lactamase_156_G194P,beta-lactamase_156_194,TEM-1,beta-lactamase_156,P62593,1.00073,NO,194,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.396,-3.912,2.516,,0.276,S,b,0.29,0.36,1.346,,67.83,POA,-1.832,0.111618,0.00392163,1.00073 beta-lactamase_625_G90C,beta-lactamase_625_90,TEM-1,beta-lactamase_625,P62593,1.00073,NO,90,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-2.091,-5.167,3.076,,0.598,T,A,0.29,0.32,0.319,,77.62,HOB,-1.52633,0.213352,0.00490273,1.00073 kka2_1:2_F263F,kka2_1:2_263,Kka2,kka2_1:2,P00552,1.00073,NO,263,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-0.911,-0.911,,,0.006,G,A,1.62,-0.12,5.275,,45.83,AHH,-0.92,0.295029,0.0172454,1.00073 beta-lactamase_156_S283L,beta-lactamase_156_283,TEM-1,beta-lactamase_156,P62593,1.00074,NO,283,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.111618,0.0429138,1.00074 beta-lactamase_2500_Q276C,beta-lactamase_2500_276,TEM-1,beta-lactamase_2500,P62593,1.00074,NO,276,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.361275,0.0191712,1.00074 kka2_1:4_K50K,kka2_1:4_50,Kka2,kka2_1:4,P00552,1.00074,NO,50,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-0.833,-0.833,,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.168804,0.00138626,1.00074 kka2_1:4_P194P,kka2_1:4_194,Kka2,kka2_1:4,P00552,1.00074,NO,194,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.846,-0.846,,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.168804,0.00314194,1.00074 kka2_1:8_V97V,kka2_1:8_97,Kka2,kka2_1:8,P00552,1.00074,NO,97,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.453,-1.453,,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.100394,0.00737869,1.00074 kka2_1:8_V97V,kka2_1:8_97,Kka2,kka2_1:8,P00552,1.00074,NO,97,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.453,-1.453,,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.100394,0.00737869,1.00074 kka2_1:8_W91W,kka2_1:8_91,Kka2,kka2_1:8,P00552,1.00074,NO,91,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-1.178,-1.178,,,0.077,E,B,1.51,0.27,2.51,,48.48,AHH,-1.51,0.100394,0.00358653,1.00074 kka2_1:8_W91W,kka2_1:8_91,Kka2,kka2_1:8,P00552,1.00074,NO,91,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-1.178,-1.178,,,0.077,E,B,1.51,0.27,2.51,,48.48,AHH,-1.51,0.100394,0.00358653,1.00074 beta-lactamase_156_D33M,beta-lactamase_156_33,TEM-1,beta-lactamase_156,P62593,1.00075,NO,33,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.321,-4.607,2.286,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.111618,0.00435556,1.00075 beta-lactamase_156_M66G,beta-lactamase_156_66,TEM-1,beta-lactamase_156,P62593,1.00075,NO,66,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.362,-3.751,2.389,,0.013,,A,0.55,-0.7,1.94,,73.08,OHH,-1.49567,0.111618,0.00412876,1.00075 beta-lactamase_625_E238K,beta-lactamase_625_238,TEM-1,beta-lactamase_625,P62593,1.00075,NO,238,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.213352,0.00743256,1.00075 beta-lactamase_625_Q267N,beta-lactamase_625_267,TEM-1,beta-lactamase_625,P62593,1.00075,NO,267,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.213352,0.0102128,1.00075 kka2_1:2_I228I,kka2_1:2_228,Kka2,kka2_1:2,P00552,1.00075,NO,228,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.142,-1.142,,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.295029,0.00458834,1.00075 kka2_1:2_R140R,kka2_1:2_140,Kka2,kka2_1:2,P00552,1.00075,NO,140,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.351,-1.351,,,0.12,H,A,1.2,0.2,0.352,,53.03,BBH,-1.885,0.295029,0.00430167,1.00075 kka2_1:2_R211R,kka2_1:2_211,Kka2,kka2_1:2,P00552,1.00075,NO,211,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-0.899,-0.899,,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.295029,0.00204888,1.00075 kka2_1:8_E111W,kka2_1:8_111,Kka2,kka2_1:8,P00552,1.00075,NO,111,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.28,-5.588,3.308,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.100394,0.00746789,1.00075 kka2_1:8_E111W,kka2_1:8_111,Kka2,kka2_1:8,P00552,1.00075,NO,111,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.28,-5.588,3.308,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.100394,0.00746789,1.00075 kka2_1:8_L102L,kka2_1:8_102,Kka2,kka2_1:8,P00552,1.00075,NO,102,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.804,-0.804,,,,T,A,1.59,-1.17,0.97,,42.42,AHH,-1.398,0.100394,0.00201332,1.00075 kka2_1:8_L102L,kka2_1:8_102,Kka2,kka2_1:8,P00552,1.00075,NO,102,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.804,-0.804,,,,T,A,1.59,-1.17,0.97,,42.42,AHH,-1.398,0.100394,0.00201332,1.00075 beta-lactamase_156_E210W,beta-lactamase_156_210,TEM-1,beta-lactamase_156,P62593,1.00076,NO,210,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.319,-5.437,3.118,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.111618,0.00663582,1.00076 beta-lactamase_39_K53A,beta-lactamase_39_53,TEM-1,beta-lactamase_39,P62593,1.00076,NO,53,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-2.313,-2.735,0.422,,0.589,,B,2.34,1.15,15.633,15.633,77.62,OBH,-2.1,0.0495842,0.00383383,1.00076 beta-lactamase_625_P250T,beta-lactamase_625_250,TEM-1,beta-lactamase_625,P62593,1.00076,NO,250,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.213352,0.00550899,1.00076 kka2_1:2_D216D,kka2_1:2_216,Kka2,kka2_1:2,P00552,1.00076,NO,216,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.785,-0.785,,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.295029,0.00229969,1.00076 kka2_1:4_H135H,kka2_1:4_135,Kka2,kka2_1:4,P00552,1.00076,NO,135,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-1.331,-1.331,,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.168804,0.00532566,1.00076 kka2_1:4_L212L,kka2_1:4_212,Kka2,kka2_1:4,P00552,1.00076,NO,212,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.904,-0.904,,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.168804,0.0031426,1.00076 kka2_1:4_V214V,kka2_1:4_214,Kka2,kka2_1:4,P00552,1.00076,NO,214,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.261,-1.261,,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.168804,0.00692782,1.00076 PSD95pdz3_S350R,PSD95pdz3_350,PSD95pdz3,PSD95pdz3,P31016,1.00076,NO,350,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.519,-3.39,1.871,4.97629,,,,,25.01,,,,HPO,-1.29133,0.0758425,0.000704883,1.00076 beta-lactamase_156_G114P,beta-lactamase_156_114,TEM-1,beta-lactamase_156,P62593,1.00077,NO,114,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.094,-3.918,2.824,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.111618,0.00224919,1.00077 beta-lactamase_156_Q97E,beta-lactamase_156_97,TEM-1,beta-lactamase_156,P62593,1.00077,NO,97,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.072,-2.167,0.095,,0.823,G,A,0.64,2.42,4.457,,77.62,PPP,-2.43833,0.111618,0.0045116,1.00077 beta-lactamase_39_L73A,beta-lactamase_39_73,TEM-1,beta-lactamase_39,P62593,1.00077,NO,73,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.507,-2.475,0.968,,,H,A,0.55,-0.64,2.09,,67.83,HHH,-1.487,0.0495842,0.00488983,1.00077 beta-lactamase_I206T,beta-lactamase_206,TEM-1,beta-lactamase,P62593,1.00077,NO,206,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-2.429,-2.077,-0.352,5.3727,0.173,H,A,1,-0.34,2.061,,77.62,HHA,-1.805,0.221079,0.00528934,1.00077 kka2_1:2_N195N,kka2_1:2_195,Kka2,kka2_1:2,P00552,1.00077,NO,195,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-0.836,-0.836,,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.295029,0.00276134,1.00077 kka2_1:2_Q100C,kka2_1:2_100,Kka2,kka2_1:2,P00552,1.00077,NO,100,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.77,-3.712,0.942,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.295029,0.0066405,1.00077 kka2_1:2_V113V,kka2_1:2_113,Kka2,kka2_1:2,P00552,1.00077,NO,113,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.233,-1.233,,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.295029,0.00650191,1.00077 kka2_1:4_L170L,kka2_1:4_170,Kka2,kka2_1:4,P00552,1.00077,NO,170,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.28,-1.28,,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.168804,0.00730791,1.00077 kka2_1:8_F203F,kka2_1:8_203,Kka2,kka2_1:8,P00552,1.00077,NO,203,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-0.911,-0.911,,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.100394,0.00318738,1.00077 kka2_1:8_F203F,kka2_1:8_203,Kka2,kka2_1:8,P00552,1.00077,NO,203,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-0.911,-0.911,,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.100394,0.00318738,1.00077 kka2_1:8_F206F,kka2_1:8_206,Kka2,kka2_1:8,P00552,1.00077,NO,206,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.349,-1.349,,,0.006,E,B,1.62,-1.21,1.052,,63.64,OHH,-1.04,0.100394,0.00936868,1.00077 kka2_1:8_F206F,kka2_1:8_206,Kka2,kka2_1:8,P00552,1.00077,NO,206,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.349,-1.349,,,0.006,E,B,1.62,-1.21,1.052,,63.64,OHH,-1.04,0.100394,0.00936868,1.00077 kka2_1:8_F48F,kka2_1:8_48,Kka2,kka2_1:8,P00552,1.00077,NO,48,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.453,-1.453,,,0.296,E,B,1.62,-0.99,14.194,14.194,55.3,HHH,-1.444,0.100394,0.00475422,1.00077 kka2_1:8_F48F,kka2_1:8_48,Kka2,kka2_1:8,P00552,1.00077,NO,48,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.453,-1.453,,,0.296,E,B,1.62,-0.99,14.194,14.194,55.3,HHH,-1.444,0.100394,0.00475422,1.00077 kka2_1:8_L193L,kka2_1:8_193,Kka2,kka2_1:8,P00552,1.00077,NO,193,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.983,-0.983,,,,G,A,1.59,-1.03,2.234,,65.53,OHO,-0.965333,0.100394,0.00480179,1.00077 kka2_1:8_L193L,kka2_1:8_193,Kka2,kka2_1:8,P00552,1.00077,NO,193,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.983,-0.983,,,,G,A,1.59,-1.03,2.234,,65.53,OHO,-0.965333,0.100394,0.00480179,1.00077 beta-lactamase_156_L196P,beta-lactamase_156_196,TEM-1,beta-lactamase_156,P62593,1.00078,NO,196,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-2.478,-3.165,0.687,,0.518,S,A,0.55,1.35,7.897,,77.62,AHH,-1.839,0.111618,0.00512144,1.00078 beta-lactamase_2500_A282D,beta-lactamase_2500_282,TEM-1,beta-lactamase_2500,P62593,1.00078,NO,282,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.361275,0.0449821,1.00078 beta-lactamase_39_P105Y,beta-lactamase_39_105,TEM-1,beta-lactamase_39,P62593,1.00078,NO,105,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.813,-4.385,3.572,,0.226,T,A,0.52,0.8,1.222,,63.29,POH,-1.01533,0.0495842,0.0011981,1.00078 beta-lactamase_39_R242H,beta-lactamase_39_242,TEM-1,beta-lactamase_39,P62593,1.00078,NO,242,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.0495842,0.00452879,1.00078 kka2_1:2_D220D,kka2_1:2_220,Kka2,kka2_1:2,P00552,1.00078,NO,220,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.787,-0.787,,,,H,A,0.75,-1.14,0.745,,46.59,PAH,-1.152,0.295029,0.00158066,1.00078 kka2_1:4_L102L,kka2_1:4_102,Kka2,kka2_1:4,P00552,1.00078,NO,102,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.804,-0.804,,,,T,A,0.55,-1.17,0.65,,42.42,AHH,-1.398,0.168804,0.00201332,1.00078 beta-lactamase_156_G216Y,beta-lactamase_156_216,TEM-1,beta-lactamase_156,P62593,1.00079,NO,216,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.477,-4.44,2.963,,0.437,I,A,0.29,-0.58,12.464,12.464,74.48,HOO,-1.68067,0.111618,0.00639568,1.00079 beta-lactamase_156_L28D,beta-lactamase_156_28,TEM-1,beta-lactamase_156,P62593,1.00079,NO,28,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.579,-3.96,2.381,,0.277,H,A,0.55,-0.16,3.262,,93.01,PHH,-2.11333,0.111618,0.00359321,1.00079 beta-lactamase_39_G265W,beta-lactamase_39_265,TEM-1,beta-lactamase_39,P62593,1.00079,NO,265,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.0495842,0.00811926,1.00079 beta-lactamase_39_P143S,beta-lactamase_39_143,TEM-1,beta-lactamase_39,P62593,1.00079,NO,143,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.967,-3.441,2.474,,0.075,H,A,0.52,-0.37,0.976,,66.78,OOB,-1.354,0.0495842,0.00114551,1.00079 beta-lactamase_625_V101S,beta-lactamase_625_101,TEM-1,beta-lactamase_625,P62593,1.00079,NO,101,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.295,-3.65,2.355,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.213352,0.00374492,1.00079 kka2_1:8_G99G,kka2_1:8_99,Kka2,kka2_1:8,P00552,1.00079,NO,99,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.596,-0.596,,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.100394,0.00186055,1.00079 kka2_1:8_G99G,kka2_1:8_99,Kka2,kka2_1:8,P00552,1.00079,NO,99,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.596,-0.596,,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.100394,0.00186055,1.00079 kka2_1:8_L259L,kka2_1:8_259,Kka2,kka2_1:8,P00552,1.00079,NO,259,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.088,-1.088,,,0.036,H,A,1.59,-0.15,1.83,,48.48,BHH,-1.15167,0.100394,0.0206964,1.00079 kka2_1:8_L259L,kka2_1:8_259,Kka2,kka2_1:8,P00552,1.00079,NO,259,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.088,-1.088,,,0.036,H,A,1.59,-0.15,1.83,,48.48,BHH,-1.15167,0.100394,0.0206964,1.00079 beta-lactamase_2500_D33T,beta-lactamase_2500_33,TEM-1,beta-lactamase_2500,P62593,1.0008,NO,33,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.321,-2.667,0.346,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.361275,0.00435556,1.0008 beta-lactamase_39_G253S,beta-lactamase_39_253,TEM-1,beta-lactamase_39,P62593,1.0008,NO,253,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.0495842,0.00786358,1.0008 beta-lactamase_39_P172E,beta-lactamase_39_172,TEM-1,beta-lactamase_39,P62593,1.0008,NO,172,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.998,-3.52,2.522,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.0495842,0.00312594,1.0008 kka2_1:4_F133F,kka2_1:4_133,Kka2,kka2_1:4,P00552,1.0008,NO,133,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-0.871,-0.871,,,0.178,.,B,0.58,0.43,0.786,,42.42,OHA,-0.871667,0.168804,0.00182168,1.0008 kka2_1:4_F206F,kka2_1:4_206,Kka2,kka2_1:4,P00552,1.0008,NO,206,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.349,-1.349,,,0.006,E,B,0.58,-1.21,1.342,,63.64,OHH,-1.04,0.168804,0.00936868,1.0008 kka2_1:4_R258R,kka2_1:4_258,Kka2,kka2_1:4,P00552,1.0008,NO,258,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.626,-1.626,,,0.316,H,A,1.2,-0.85,2.655,,53.03,HBH,-1.25933,0.168804,0.00983174,1.0008 kka2_1:8_S32S,kka2_1:8_32,Kka2,kka2_1:8,P00552,1.0008,NO,32,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-0.804,-0.804,,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.100394,0.00149998,1.0008 kka2_1:8_S32S,kka2_1:8_32,Kka2,kka2_1:8,P00552,1.0008,NO,32,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-0.804,-0.804,,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.100394,0.00149998,1.0008 beta-lactamase_156_T186W,beta-lactamase_156_186,TEM-1,beta-lactamase_156,P62593,1.00081,NO,186,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.522,-5.446,2.924,,0.396,H,A,0.22,-0.28,16.606,16.606,77.62,HPP,-1.77633,0.111618,0.00485034,1.00081 beta-lactamase_39_E279D,beta-lactamase_39_279,TEM-1,beta-lactamase_39,P62593,1.00081,NO,279,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.0495842,0.0192826,1.00081 beta-lactamase_625_V101Y,beta-lactamase_625_101,TEM-1,beta-lactamase_625,P62593,1.00081,NO,101,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.295,-4.116,2.821,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.213352,0.00374492,1.00081 kka2_1:2_A224A,kka2_1:2_224,Kka2,kka2_1:2,P00552,1.00081,NO,224,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.977,-0.977,,,,H,A,0.46,-1.26,1.646,,63.64,HHP,-1.41033,0.295029,0.00352047,1.00081 beta-lactamase_39_A183W,beta-lactamase_39_183,TEM-1,beta-lactamase_39,P62593,1.00082,NO,183,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.231,-5.466,4.235,,0.155,H,A,0.46,-0.91,1.237,,77.62,HHH,-1.53367,0.0495842,0.00296631,1.00082 beta-lactamase_39_I125L,beta-lactamase_39_125,TEM-1,beta-lactamase_39,P62593,1.00082,NO,125,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.441,-1.939,0.498,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.0495842,0.00383964,1.00082 beta-lactamase_625_A246G,beta-lactamase_625_246,TEM-1,beta-lactamase_625,P62593,1.00082,NO,246,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.121,-3.675,1.554,,0.01,E,B,0.46,-1.01,1.201,,73.78,HHH,-1.55633,0.213352,0.00569458,1.00082 beta-lactamase_625_H151Y,beta-lactamase_625_151,TEM-1,beta-lactamase_625,P62593,1.00082,NO,151,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-2.96,-4.115,1.155,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.213352,0.00216946,1.00082 beta-lactamase_A148I,beta-lactamase_148,TEM-1,beta-lactamase,P62593,1.00082,NO,148,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.757,-4.049,2.292,5.28111,0.379,H,A,0.52,-0.55,2.117,,72.73,PHH,-1.40167,0.221079,0.00547053,1.00082 beta-lactamase_A280H,beta-lactamase_280,TEM-1,beta-lactamase,P62593,1.00082,NO,280,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.708,-4.588,2.88,4.74932,0.379,H,A,0.52,-0.72,1.785,,68.18,OHP,-1.66433,0.221079,0.0530888,1.00082 beta-lactamase_E195Q,beta-lactamase_195,TEM-1,beta-lactamase,P62593,1.00082,NO,195,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.186,-2.527,0.341,7.28489,1.016,S,A,1.52,0.85,2.583,,77.62,OAH,-2.02,0.221079,0.00496565,1.00082 kka2_1:1_V186V,kka2_1:1_186,Kka2,kka2_1:1,P00552,1.00082,NO,186,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.011,-1.011,,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.520039,0.00409703,1.00082 kka2_1:2_G74G,kka2_1:2_74,Kka2,kka2_1:2,P00552,1.00082,NO,74,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.18,-1.18,,,0.621,T,l,0.75,0.2,1.446,,64.39,POH,-1.91667,0.295029,0.00587035,1.00082 kka2_1:4_G30G,kka2_1:4_30,Kka2,kka2_1:4,P00552,1.00082,NO,30,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.596,-0.596,,,0.54,S,g,0.29,3.76,,,,HOO,-1.51133,0.168804,0.00159208,1.00082 kka2_1:8_A237A,kka2_1:8_237,Kka2,kka2_1:8,P00552,1.00082,NO,237,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.12,-2.12,,,0.068,H,A,0.46,-0.71,0.449,,92.05,HHA,-2.10433,0.100394,0.012257,1.00082 kka2_1:8_A237A,kka2_1:8_237,Kka2,kka2_1:8,P00552,1.00082,NO,237,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.12,-2.12,,,0.068,H,A,0.46,-0.71,0.449,,92.05,HHA,-2.10433,0.100394,0.012257,1.00082 kka2_1:8_I115I,kka2_1:8_115,Kka2,kka2_1:8,P00552,1.00082,NO,115,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.606,-1.606,,,0.105,H,A,1.52,-1.18,4.064,,65.53,PHH,-2.205,0.100394,0.00836567,1.00082 kka2_1:8_I115I,kka2_1:8_115,Kka2,kka2_1:8,P00552,1.00082,NO,115,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.606,-1.606,,,0.105,H,A,1.52,-1.18,4.064,,65.53,PHH,-2.205,0.100394,0.00836567,1.00082 kka2_1:8_I221I,kka2_1:8_221,Kka2,kka2_1:8,P00552,1.00082,NO,221,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.739,-1.739,,,,H,A,1.52,-1.15,1.599,,71.59,AHH,-1.08367,0.100394,0.00945908,1.00082 kka2_1:8_I221I,kka2_1:8_221,Kka2,kka2_1:8,P00552,1.00082,NO,221,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.739,-1.739,,,,H,A,1.52,-1.15,1.599,,71.59,AHH,-1.08367,0.100394,0.00945908,1.00082 kka2_1:8_W69W,kka2_1:8_69,Kka2,kka2_1:8,P00552,1.00082,NO,69,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-0.859,-0.859,,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.100394,0.0012874,1.00082 kka2_1:8_W69W,kka2_1:8_69,Kka2,kka2_1:8,P00552,1.00082,NO,69,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-0.859,-0.859,,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.100394,0.0012874,1.00082 beta-lactamase_156_G52W,beta-lactamase_156_52,TEM-1,beta-lactamase_156,P62593,1.00083,NO,52,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.149,-5.364,4.215,,0.299,,l,0.29,-0.04,1.179,,64.69,POB,-1.66267,0.111618,0.00340138,1.00083 beta-lactamase_2500_Q37H,beta-lactamase_2500_37,TEM-1,beta-lactamase_2500,P62593,1.00083,NO,37,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.134,-3.314,1.18,,0.613,H,A,0.64,1.98,1.318,,73.08,APH,-2.06967,0.361275,0.00425833,1.00083 kka2_1:2_A144A,kka2_1:2_144,Kka2,kka2_1:2,P00552,1.00083,NO,144,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.859,-0.859,,,,H,A,0.46,0.21,6.844,,52.65,BHB,-1.72933,0.295029,0.00231095,1.00083 kka2_1:4_G245G,kka2_1:4_245,Kka2,kka2_1:4,P00552,1.00083,NO,245,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.812,-0.812,,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.168804,0.00683899,1.00083 kka2_1:4_L123L,kka2_1:4_123,Kka2,kka2_1:4,P00552,1.00083,NO,123,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.888,-0.888,,,0.007,H,A,0.55,-0.4,1.447,,48.86,BHB,-1.301,0.168804,0.00325188,1.00083 kka2_1:4_I207I,kka2_1:4_207,Kka2,kka2_1:4,P00552,1.00084,NO,207,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.175,-1.175,,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.168804,0.00611824,1.00084 kka2_1:4_R66R,kka2_1:4_66,Kka2,kka2_1:4,P00552,1.00084,NO,66,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-0.922,-0.922,,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.168804,0.00161025,1.00084 kka2_1:8_V36V,kka2_1:8_36,Kka2,kka2_1:8,P00552,1.00084,NO,36,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-0.898,-0.898,,,0.292,E,B,1.48,0.21,0.938,,52.27,HHH,-1.484,0.100394,0.00245633,1.00084 kka2_1:8_V36V,kka2_1:8_36,Kka2,kka2_1:8,P00552,1.00084,NO,36,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-0.898,-0.898,,,0.292,E,B,1.48,0.21,0.938,,52.27,HHH,-1.484,0.100394,0.00245633,1.00084 beta-lactamase_156_D174G,beta-lactamase_156_174,TEM-1,beta-lactamase_156,P62593,1.00085,NO,174,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.738,-3.133,2.395,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.111618,0.00125633,1.00085 kka2_1:2_L232L,kka2_1:2_232,Kka2,kka2_1:2,P00552,1.00085,NO,232,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.514,-1.514,,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.295029,0.00800103,1.00085 kka2_1:2_T187T,kka2_1:2_187,Kka2,kka2_1:2,P00552,1.00085,NO,187,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.273,-1.273,,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.295029,0.00693073,1.00085 kka2_1:2_W236W,kka2_1:2_236,Kka2,kka2_1:2,P00552,1.00085,NO,236,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-1.363,-1.363,,,0.303,H,A,1.51,-0.76,5.58,,48.48,AHH,-1.81267,0.295029,0.0088796,1.00085 kka2_1:8_H124H,kka2_1:8_124,Kka2,kka2_1:8,P00552,1.00085,NO,124,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-0.84,-0.84,,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.100394,0.00211296,1.00085 kka2_1:8_H124H,kka2_1:8_124,Kka2,kka2_1:8,P00552,1.00085,NO,124,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-0.84,-0.84,,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.100394,0.00211296,1.00085 beta-lactamase_39_A246F,beta-lactamase_39_246,TEM-1,beta-lactamase_39,P62593,1.00086,NO,246,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.121,-2.727,0.606,,0.01,E,B,0.46,-1.01,1.331,,73.78,HHH,-1.55633,0.0495842,0.00569458,1.00086 beta-lactamase_39_I245C,beta-lactamase_39_245,TEM-1,beta-lactamase_39,P62593,1.00086,NO,245,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.0495842,0.00391032,1.00086 kka2_1:4_V36V,kka2_1:4_36,Kka2,kka2_1:4,P00552,1.00086,NO,36,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-0.898,-0.898,,,0.292,E,B,0.44,0.21,0.278,,52.27,HHH,-1.484,0.168804,0.00245633,1.00086 beta-lactamase_156_G194V,beta-lactamase_156_194,TEM-1,beta-lactamase_156,P62593,1.00087,NO,194,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.396,-3.736,2.34,,0.276,S,b,0.29,0.36,1.346,,67.83,POA,-1.832,0.111618,0.00392163,1.00087 beta-lactamase_2500_D252F,beta-lactamase_2500_252,TEM-1,beta-lactamase_2500,P62593,1.00087,NO,252,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.94,,,,0.766,,B,1.59,1.16,,,67.83,OAO,-2.0965,0.361275,0.00575769,1.00087 kka2_1:2_H188H,kka2_1:2_188,Kka2,kka2_1:2,P00552,1.00087,NO,188,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-0.913,-0.913,,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.295029,0.00273139,1.00087 kka2_1:4_F264F,kka2_1:4_264,Kka2,kka2_1:4,P00552,1.00087,NO,264,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.02,-1.02,,,0.296,,?,1.62,0.02,1.93,,71.59,HHO,-0.9655,0.168804,,1.00087 kka2_1:8_L170L,kka2_1:8_170,Kka2,kka2_1:8,P00552,1.00087,NO,170,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.28,-1.28,,,0.029,H,A,1.59,0.11,1.453,,62.5,AHH,-1.534,0.100394,0.00730791,1.00087 kka2_1:8_L170L,kka2_1:8_170,Kka2,kka2_1:8,P00552,1.00087,NO,170,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.28,-1.28,,,0.029,H,A,1.59,0.11,1.453,,62.5,AHH,-1.534,0.100394,0.00730791,1.00087 kka2_1:8_L241L,kka2_1:8_241,Kka2,kka2_1:8,P00552,1.00087,NO,241,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.158,-1.158,,,0.08,H,A,1.59,-0.82,1.136,,63.26,HHH,-1.58533,0.100394,0.0117299,1.00087 kka2_1:8_L241L,kka2_1:8_241,Kka2,kka2_1:8,P00552,1.00087,NO,241,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.158,-1.158,,,0.08,H,A,1.59,-0.82,1.136,,63.26,HHH,-1.58533,0.100394,0.0117299,1.00087 kka2_1:8_R66R,kka2_1:8_66,Kka2,kka2_1:8,P00552,1.00087,NO,66,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-0.922,-0.922,,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.100394,0.00161025,1.00087 kka2_1:8_R66R,kka2_1:8_66,Kka2,kka2_1:8,P00552,1.00087,NO,66,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-0.922,-0.922,,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.100394,0.00161025,1.00087 beta-lactamase_156_P255T,beta-lactamase_156_255,TEM-1,beta-lactamase_156,P62593,1.00088,NO,255,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.111618,0.00499612,1.00088 beta-lactamase_2500_E46N,beta-lactamase_2500_46,TEM-1,beta-lactamase_2500,P62593,1.00088,NO,46,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.94,-4.011,2.071,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.361275,0.00427568,1.00088 beta-lactamase_2500_N173H,beta-lactamase_2500_173,TEM-1,beta-lactamase_2500,P62593,1.00088,NO,173,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-2.663,-4.635,1.972,,1.044,T,l,0.61,1.25,1.88,,77.62,OPA,-1.46633,0.361275,0.0033769,1.00088 beta-lactamase_39_R59G,beta-lactamase_39_59,TEM-1,beta-lactamase_39,P62593,1.00088,NO,59,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.345,-3.412,2.067,,0.329,S,L,1.2,-0.09,1.806,,73.08,HBO,-2.24267,0.0495842,0.00318082,1.00088 beta-lactamase_625_L49S,beta-lactamase_625_49,TEM-1,beta-lactamase_625,P62593,1.00088,NO,49,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.897,-2.417,0.52,,0.131,T,A,0.55,0.04,3.112,,64.69,AHP,-1.99233,0.213352,0.00401477,1.00088 beta-lactamase_625_S201G,beta-lactamase_625_201,TEM-1,beta-lactamase_625,P62593,1.00088,NO,201,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.183,-2.39,1.207,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.213352,0.00198815,1.00088 beta-lactamase_625_S51T,beta-lactamase_625_51,TEM-1,beta-lactamase_625,P62593,1.00088,NO,51,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.526,-1.846,0.32,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.213352,0.00504821,1.00088 E1_Ubiquitin_A46I,E1_Ubiquitin_46,Uba1,E1_Ubiquitin,P0CG63,1.00088,NO,46,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.367,-3.466,2.099,,0.398,T,L,,-0.8,,,,HHO,-1.17167,0.18783,0.004233,1.00088 E1_Ubiquitin_G47M,E1_Ubiquitin_47,Uba1,E1_Ubiquitin,P0CG63,1.00088,NO,47,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.999,-4.589,3.59,,0.057,T,l,,-1.21,,,,HOB,-1.195,0.18783,0.00142261,1.00088 E1_Ubiquitin_L73S,E1_Ubiquitin_73,Uba1,E1_Ubiquitin,P0CG63,1.00088,NO,73,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.039,-3.428,2.389,,0.518,,B,1.3,1,,,,BHB,-1.175,0.18783,0.00111236,1.00088 E1_Ubiquitin_R42I,E1_Ubiquitin_42,Uba1,E1_Ubiquitin,P0CG63,1.00088,NO,42,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.302,-3.881,2.579,,0.244,E,B,,-0.54,,,,PBH,-1.24667,0.18783,0.00224033,1.00088 E1_Ubiquitin_T68D,E1_Ubiquitin_68,Uba1,E1_Ubiquitin,P0CG63,1.00088,NO,68,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,,,,,,,,,,,,,OPH,-1.039,0.18783,0.00314321,1.00088 kka2_1:2_G210G,kka2_1:2_210,Kka2,kka2_1:2,P00552,1.00088,NO,210,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.095,-1.095,,,0.103,T,A,0.29,-0.62,0.271,,50,OOB,-0.966667,0.295029,0.00598378,1.00088 kka2_1:4_D159D,kka2_1:4_159,Kka2,kka2_1:4,P00552,1.00088,NO,159,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.82,-0.82,,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.168804,0.0030485,1.00088 beta-lactamase_156_L55C,beta-lactamase_156_55,TEM-1,beta-lactamase_156,P62593,1.00089,NO,55,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.86,-4.909,3.049,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.111618,0.00403741,1.00089 beta-lactamase_156_T264V,beta-lactamase_156_264,TEM-1,beta-lactamase_156,P62593,1.00089,NO,264,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.111618,0.0119399,1.00089 beta-lactamase_39_K53D,beta-lactamase_39_53,TEM-1,beta-lactamase_39,P62593,1.00089,NO,53,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-2.313,-3.725,1.412,,0.589,,B,2.34,1.15,15.633,15.633,77.62,OBH,-2.1,0.0495842,0.00383383,1.00089 beta-lactamase_39_R189C,beta-lactamase_39_189,TEM-1,beta-lactamase_39,P62593,1.00089,NO,189,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.844,-5.229,3.385,,0.278,H,A,1.2,1.01,12.11,12.11,72.73,HBB,-1.668,0.0495842,0.0050699,1.00089 beta-lactamase_39_T263N,beta-lactamase_39_263,TEM-1,beta-lactamase_39,P62593,1.00089,NO,263,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.0495842,0.0110582,1.00089 kka2_1:4_E262E,kka2_1:4_262,Kka2,kka2_1:4,P00552,1.00089,NO,262,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-0.829,-0.829,,,0.059,G,A,1.04,-0.18,2.383,,42.42,AAH,-0.816,0.168804,0.0191586,1.00089 kka2_1:4_L174L,kka2_1:4_174,Kka2,kka2_1:4,P00552,1.00089,NO,174,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.952,-0.952,,,,H,A,0.55,-0.31,1.339,,51.89,BHB,-2.08533,0.168804,0.00438501,1.00089 kka2_1:8_A224A,kka2_1:8_224,Kka2,kka2_1:8,P00552,1.00089,NO,224,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.977,-0.977,,,,H,A,0.46,-1.26,0.357,,63.64,HHP,-1.41033,0.100394,0.00352047,1.00089 kka2_1:8_A224A,kka2_1:8_224,Kka2,kka2_1:8,P00552,1.00089,NO,224,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.977,-0.977,,,,H,A,0.46,-1.26,0.357,,63.64,HHP,-1.41033,0.100394,0.00352047,1.00089 kka2_1:8_F133F,kka2_1:8_133,Kka2,kka2_1:8,P00552,1.00089,NO,133,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-0.871,-0.871,,,0.178,,B,1.62,0.43,1.816,,42.42,OHA,-0.871667,0.100394,0.00182168,1.00089 kka2_1:8_F133F,kka2_1:8_133,Kka2,kka2_1:8,P00552,1.00089,NO,133,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-0.871,-0.871,,,0.178,,B,1.62,0.43,1.816,,42.42,OHA,-0.871667,0.100394,0.00182168,1.00089 kka2_1:8_L232L,kka2_1:8_232,Kka2,kka2_1:8,P00552,1.00089,NO,232,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.514,-1.514,,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.100394,0.00800103,1.00089 kka2_1:8_L232L,kka2_1:8_232,Kka2,kka2_1:8,P00552,1.00089,NO,232,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.514,-1.514,,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.100394,0.00800103,1.00089 beta-lactamase_625_A148F,beta-lactamase_625_148,TEM-1,beta-lactamase_625,P62593,1.0009,NO,148,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.757,-4.389,2.632,,0.379,H,A,0.46,-0.55,1.359,,72.73,PHH,-1.40167,0.213352,0.00547053,1.0009 beta-lactamase_625_M270C,beta-lactamase_625_270,TEM-1,beta-lactamase_625,P62593,1.0009,NO,270,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.213352,0.00767762,1.0009 beta-lactamase_625_Y103W,beta-lactamase_625_103,TEM-1,beta-lactamase_625,P62593,1.0009,NO,103,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-1.33,-2.453,1.123,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.213352,0.00443048,1.0009 kka2_1:2_L241L,kka2_1:2_241,Kka2,kka2_1:2,P00552,1.0009,NO,241,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.158,-1.158,,,0.08,H,A,0.55,-0.82,1.598,,63.26,HHH,-1.58533,0.295029,0.0117299,1.0009 kka2_1:4_A224A,kka2_1:4_224,Kka2,kka2_1:4,P00552,1.0009,NO,224,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.977,-0.977,,,,H,A,0.46,-1.26,0.93,,63.64,HHP,-1.41033,0.168804,0.00352047,1.0009 kka2_1:4_I196I,kka2_1:4_196,Kka2,kka2_1:4,P00552,1.0009,NO,196,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-2.115,-2.115,,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.168804,0.0107273,1.0009 kka2_1:4_L193L,kka2_1:4_193,Kka2,kka2_1:4,P00552,1.0009,NO,193,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.983,-0.983,,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.168804,0.00480179,1.0009 kka2_1:8_K50K,kka2_1:8_50,Kka2,kka2_1:8,P00552,1.0009,NO,50,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-0.833,-0.833,,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.100394,0.00138626,1.0009 kka2_1:8_K50K,kka2_1:8_50,Kka2,kka2_1:8,P00552,1.0009,NO,50,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-0.833,-0.833,,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.100394,0.00138626,1.0009 kka2_1:8_M116R,kka2_1:8_116,Kka2,kka2_1:8,P00552,1.0009,NO,116,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-2.482,-4.144,1.662,,,H,A,1.59,-0.88,4.659,,71.59,HHH,-1.63867,0.100394,0.00745147,1.0009 kka2_1:8_M116R,kka2_1:8_116,Kka2,kka2_1:8,P00552,1.0009,NO,116,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-2.482,-4.144,1.662,,,H,A,1.59,-0.88,4.659,,71.59,HHH,-1.63867,0.100394,0.00745147,1.0009 beta-lactamase_156_A225C,beta-lactamase_156_225,TEM-1,beta-lactamase_156,P62593,1.00091,NO,225,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.845,-5.105,3.26,,1,T,B,0.46,-0.38,11.722,11.722,74.48,OHO,-1.39967,0.111618,0.00465057,1.00091 beta-lactamase_156_A247F,beta-lactamase_156_247,TEM-1,beta-lactamase_156,P62593,1.00091,NO,247,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.111618,0.00611275,1.00091 beta-lactamase_156_L28M,beta-lactamase_156_28,TEM-1,beta-lactamase_156,P62593,1.00091,NO,28,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.579,-4.156,2.577,,0.277,H,A,0.55,-0.16,3.262,,93.01,PHH,-2.11333,0.111618,0.00359321,1.00091 beta-lactamase_156_S221I,beta-lactamase_156_221,TEM-1,beta-lactamase_156,P62593,1.00091,NO,221,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.754,-3.812,2.058,,0.624,H,A,0.27,-0.2,17.729,17.729,74.48,BPH,-1.59967,0.111618,0.0046094,1.00091 beta-lactamase_625_H110C,beta-lactamase_625_110,TEM-1,beta-lactamase_625,P62593,1.00091,NO,110,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-1.706,-5.217,3.511,,0.341,G,a,0.17,1.08,31.31,31.31,64.69,BBH,-1.73333,0.213352,0.00441499,1.00091 kka2_1:4_A237A,kka2_1:4_237,Kka2,kka2_1:4,P00552,1.00091,NO,237,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.12,-2.12,,,0.068,H,A,0.46,-0.71,2.444,,92.05,HHA,-2.10433,0.168804,0.012257,1.00091 beta-lactamase_156_N50S,beta-lactamase_156_50,TEM-1,beta-lactamase_156,P62593,1.00092,NO,50,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-2.979,-3.331,0.352,,0.912,T,A,0.61,1.24,13.295,13.295,77.62,HPP,-2.134,0.111618,0.0047211,1.00092 beta-lactamase_2500_A148V,beta-lactamase_2500_148,TEM-1,beta-lactamase_2500,P62593,1.00092,NO,148,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.757,-3.631,1.874,,0.379,H,A,0.46,-0.55,2.117,,72.73,PHH,-1.40167,0.361275,0.00547053,1.00092 kka2_1:8_A215A,kka2_1:8_215,Kka2,kka2_1:8,P00552,1.00092,NO,215,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.968,-0.968,,,0.039,E,B,1.04,-0.59,2.77,,50.38,HHA,-1.00467,0.100394,0.00529129,1.00092 kka2_1:8_A215A,kka2_1:8_215,Kka2,kka2_1:8,P00552,1.00092,NO,215,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.968,-0.968,,,0.039,E,B,1.04,-0.59,2.77,,50.38,HHA,-1.00467,0.100394,0.00529129,1.00092 kka2_1:8_A229D,kka2_1:8_229,Kka2,kka2_1:8,P00552,1.00092,NO,229,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.739,-3.667,1.928,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.100394,0.00942138,1.00092 kka2_1:8_A229D,kka2_1:8_229,Kka2,kka2_1:8,P00552,1.00092,NO,229,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.739,-3.667,1.928,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.100394,0.00942138,1.00092 kka2_1:8_G30G,kka2_1:8_30,Kka2,kka2_1:8,P00552,1.00092,NO,30,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.596,-0.596,,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.100394,0.00159208,1.00092 kka2_1:8_G30G,kka2_1:8_30,Kka2,kka2_1:8,P00552,1.00092,NO,30,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.596,-0.596,,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.100394,0.00159208,1.00092 kka2_1:8_L123L,kka2_1:8_123,Kka2,kka2_1:8,P00552,1.00092,NO,123,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.888,-0.888,,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.100394,0.00325188,1.00092 kka2_1:8_L123L,kka2_1:8_123,Kka2,kka2_1:8,P00552,1.00092,NO,123,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.888,-0.888,,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.100394,0.00325188,1.00092 kka2_1:8_L223L,kka2_1:8_223,Kka2,kka2_1:8,P00552,1.00092,NO,223,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.861,-0.861,,,,H,A,1.59,-1.24,1.017,,50,HHH,-0.854333,0.100394,0.00253574,1.00092 kka2_1:8_L223L,kka2_1:8_223,Kka2,kka2_1:8,P00552,1.00092,NO,223,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.861,-0.861,,,,H,A,1.59,-1.24,1.017,,50,HHH,-0.854333,0.100394,0.00253574,1.00092 kka2_1:8_L260L,kka2_1:8_260,Kka2,kka2_1:8,P00552,1.00092,NO,260,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.741,-0.741,,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.100394,0.0233782,1.00092 kka2_1:8_L260L,kka2_1:8_260,Kka2,kka2_1:8,P00552,1.00092,NO,260,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.741,-0.741,,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.100394,0.0233782,1.00092 kka2_1:8_R258R,kka2_1:8_258,Kka2,kka2_1:8,P00552,1.00092,NO,258,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.626,-1.626,,,0.316,H,A,0.16,-0.85,5.58,,53.03,HBH,-1.25933,0.100394,0.00983174,1.00092 kka2_1:8_R258R,kka2_1:8_258,Kka2,kka2_1:8,P00552,1.00092,NO,258,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.626,-1.626,,,0.316,H,A,0.16,-0.85,5.58,,53.03,HBH,-1.25933,0.100394,0.00983174,1.00092 beta-lactamase_156_D207S,beta-lactamase_156_207,TEM-1,beta-lactamase_156,P62593,1.00093,NO,207,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.064,-2.656,0.592,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.111618,0.00592942,1.00093 beta-lactamase_156_K32F,beta-lactamase_156_32,TEM-1,beta-lactamase_156,P62593,1.00093,NO,32,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.984,-4.328,2.344,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.111618,0.00401283,1.00093 beta-lactamase_156_Q97A,beta-lactamase_156_97,TEM-1,beta-lactamase_156,P62593,1.00093,NO,97,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.072,-2.26,0.188,,0.823,G,A,0.64,2.42,4.457,,77.62,PPP,-2.43833,0.111618,0.0045116,1.00093 beta-lactamase_2500_K254M,beta-lactamase_2500_254,TEM-1,beta-lactamase_2500,P62593,1.00093,NO,254,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.361275,0.00369,1.00093 beta-lactamase_39_A230I,beta-lactamase_39_230,TEM-1,beta-lactamase_39,P62593,1.00093,NO,230,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.154,-3.843,2.689,,0.01,E,B,0.46,-1.17,1.171,,50,HHA,-1.079,0.0495842,0.00516841,1.00093 beta-lactamase_39_L73S,beta-lactamase_39_73,TEM-1,beta-lactamase_39,P62593,1.00093,NO,73,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.507,-3.664,2.157,,,H,A,0.55,-0.64,2.09,,67.83,HHH,-1.487,0.0495842,0.00488983,1.00093 kka2_1:2_A222A,kka2_1:2_222,Kka2,kka2_1:2,P00552,1.00093,NO,222,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.725,-0.725,,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.295029,0.00207657,1.00093 kka2_1:4_G210G,kka2_1:4_210,Kka2,kka2_1:4,P00552,1.00093,NO,210,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.095,-1.095,,,0.103,T,A,0.29,-0.62,0.271,,50,OOB,-0.966667,0.168804,0.00598378,1.00093 beta-lactamase_156_K144A,beta-lactamase_156_144,TEM-1,beta-lactamase_156,P62593,1.00094,NO,144,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-2.388,-2.013,-0.375,,0.863,H,A,2.34,1.27,2.073,,77.62,OBA,-1.904,0.111618,0.00481141,1.00094 beta-lactamase_625_F149Y,beta-lactamase_625_149,TEM-1,beta-lactamase_625,P62593,1.00094,NO,149,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.299,-1.705,0.406,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.213352,0.00418462,1.00094 kka2_1:1_P76P,kka2_1:1_76,Kka2,kka2_1:1,P00552,1.00094,NO,76,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.449,-1.449,,,0.331,.,B,0.52,-0.41,0.345,,63.64,HOO,-1.662,0.520039,0.00625685,1.00094 kka2_1:2_G99G,kka2_1:2_99,Kka2,kka2_1:2,P00552,1.00094,NO,99,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.596,-0.596,,,0.368,S,g,0.29,-0.87,,,,OOP,-1.63067,0.295029,0.00186055,1.00094 kka2_1:2_R217R,kka2_1:2_217,Kka2,kka2_1:2,P00552,1.00094,NO,217,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.158,-1.158,,,0.252,T,A,1.2,-0.59,0.381,,52.27,ABH,-1.127,0.295029,0.0047191,1.00094 kka2_1:4_L223L,kka2_1:4_223,Kka2,kka2_1:4,P00552,1.00094,NO,223,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.861,-0.861,,,,H,A,1.59,-1.24,1.268,,50,HHH,-0.854333,0.168804,0.00253574,1.00094 kka2_1:8_D159D,kka2_1:8_159,Kka2,kka2_1:8,P00552,1.00094,NO,159,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.82,-0.82,,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.100394,0.0030485,1.00094 kka2_1:8_D159D,kka2_1:8_159,Kka2,kka2_1:8,P00552,1.00094,NO,159,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.82,-0.82,,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.100394,0.0030485,1.00094 kka2_1:8_L174L,kka2_1:8_174,Kka2,kka2_1:8,P00552,1.00094,NO,174,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.952,-0.952,,,,H,A,1.59,-0.31,1.204,,51.89,BHB,-2.08533,0.100394,0.00438501,1.00094 kka2_1:8_L174L,kka2_1:8_174,Kka2,kka2_1:8,P00552,1.00094,NO,174,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.952,-0.952,,,,H,A,1.59,-0.31,1.204,,51.89,BHB,-2.08533,0.100394,0.00438501,1.00094 beta-lactamase_156_S241T,beta-lactamase_156_241,TEM-1,beta-lactamase_156,P62593,1.00095,NO,241,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.111618,0.00452736,1.00095 beta-lactamase_625_H156F,beta-lactamase_625_156,TEM-1,beta-lactamase_625,P62593,1.00095,NO,156,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-3.156,-4.428,1.272,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.213352,0.00468596,1.00095 kka2_1:2_D208D,kka2_1:2_208,Kka2,kka2_1:2,P00552,1.00095,NO,208,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.708,-0.708,,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.295029,0.00212588,1.00095 kka2_1:4_F203F,kka2_1:4_203,Kka2,kka2_1:4,P00552,1.00095,NO,203,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-0.911,-0.911,,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.168804,0.00318738,1.00095 kka2_1:8_G210G,kka2_1:8_210,Kka2,kka2_1:8,P00552,1.00095,NO,210,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.095,-1.095,,,0.103,T,A,0.75,-0.62,2.687,,50,OOB,-0.966667,0.100394,0.00598378,1.00095 kka2_1:8_G210G,kka2_1:8_210,Kka2,kka2_1:8,P00552,1.00095,NO,210,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.095,-1.095,,,0.103,T,A,0.75,-0.62,2.687,,50,OOB,-0.966667,0.100394,0.00598378,1.00095 kka2_1:8_I207I,kka2_1:8_207,Kka2,kka2_1:8,P00552,1.00095,NO,207,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.175,-1.175,,,0.293,,B,1.52,-1.12,1.306,,56.06,HHA,-1.07733,0.100394,0.00611824,1.00095 kka2_1:8_I207I,kka2_1:8_207,Kka2,kka2_1:8,P00552,1.00095,NO,207,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.175,-1.175,,,0.293,,B,1.52,-1.12,1.306,,56.06,HHA,-1.07733,0.100394,0.00611824,1.00095 kka2_1:8_M197M,kka2_1:8_197,Kka2,kka2_1:8,P00552,1.00095,NO,197,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.707,-1.707,,,0.121,E,B,1.59,-1.19,4.408,,65.53,HHH,-1.847,0.100394,0.00921295,1.00095 kka2_1:8_M197M,kka2_1:8_197,Kka2,kka2_1:8,P00552,1.00095,NO,197,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.707,-1.707,,,0.121,E,B,1.59,-1.19,4.408,,65.53,HHH,-1.847,0.100394,0.00921295,1.00095 beta-lactamase_156_P105L,beta-lactamase_156_105,TEM-1,beta-lactamase_156,P62593,1.00096,NO,105,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.813,-3.581,2.768,,0.226,T,A,0.52,0.8,1.154,,63.29,POH,-1.01533,0.111618,0.0011981,1.00096 beta-lactamase_39_R162V,beta-lactamase_39_162,TEM-1,beta-lactamase_39,P62593,1.00096,NO,162,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.016,-3.642,2.626,,0.124,S,B,1.2,-0.37,31.656,31.656,64.69,ABH,-1.25,0.0495842,0.000561334,1.00096 gb1_D266T,gb1_266,gb1,gb1,P06654,1.00096,NO,266,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.261,-3.321,2.06,,,,,,,0.638,,45.54,HAO,-1.59333,0.177985,0.00394694,1.00096 gb1_K276E,gb1_276,gb1,gb1,P06654,1.00096,NO,276,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.456,-2.92,1.464,,,,,,,0.236,,12.72,PBP,-1.65133,0.177985,0.00620493,1.00096 gb1_K276T,gb1_276,gb1,gb1,P06654,1.00096,NO,276,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.456,-3.261,1.805,,,,,,,0.236,,12.72,PBP,-1.65133,0.177985,0.00620493,1.00096 kka2_1:2_A119A,kka2_1:2_119,Kka2,kka2_1:2,P00552,1.00096,NO,119,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.073,-1.073,,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.295029,0.00441074,1.00096 kka2_1:2_R226R,kka2_1:2_226,Kka2,kka2_1:2,P00552,1.00096,NO,226,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.392,-1.392,,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.295029,0.0108032,1.00096 beta-lactamase_0_I45Q,beta-lactamase_0_45,TEM-1,beta-lactamase_0,P62593,1.00097,NO,45,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-2.421,-3.24,0.819,,,E,B,0.48,-0.3,1.375,,77.62,HHA,-2.30267,0.0500837,0.00452842,1.00097 beta-lactamase_156_E279D,beta-lactamase_156_279,TEM-1,beta-lactamase_156,P62593,1.00097,NO,279,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.111618,0.0192826,1.00097 beta-lactamase_156_S221G,beta-lactamase_156_221,TEM-1,beta-lactamase_156,P62593,1.00097,NO,221,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.754,-3.136,1.382,,0.624,H,A,0.27,-0.2,17.729,17.729,74.48,BPH,-1.59967,0.111618,0.0046094,1.00097 beta-lactamase_39_L150A,beta-lactamase_39_150,TEM-1,beta-lactamase_39,P62593,1.00097,NO,150,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.326,-2.051,0.725,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.0495842,0.00463171,1.00097 beta-lactamase_39_P25A,beta-lactamase_39_25,TEM-1,beta-lactamase_39,P62593,1.00097,NO,25,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.526,-2.222,0.696,,0.624,H,A,0.52,0.14,1.157,,73.08,BOA,-2.15367,0.0495842,0.00347571,1.00097 beta-lactamase_625_E169N,beta-lactamase_625_169,TEM-1,beta-lactamase_625,P62593,1.00097,NO,169,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.23,-3.55,2.32,,0.337,,A,1.04,1,1.806,,73.08,PAH,-1.16533,0.213352,0.00400994,1.00097 kka2_1:2_G205G,kka2_1:2_205,Kka2,kka2_1:2,P00552,1.00097,NO,205,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.596,-0.596,,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.295029,0.00221855,1.00097 kka2_1:4_T187T,kka2_1:4_187,Kka2,kka2_1:4,P00552,1.00097,NO,187,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.273,-1.273,,,0.007,E,B,0.22,-0.85,2.73,,52.27,HPB,-1.06567,0.168804,0.00693073,1.00097 kka2_1:8_A117A,kka2_1:8_117,Kka2,kka2_1:8,P00552,1.00097,NO,117,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.828,-0.828,,,,H,A,1.04,-0.78,0.755,,45.83,HHA,-1.79333,0.100394,0.00282984,1.00097 kka2_1:8_A117A,kka2_1:8_117,Kka2,kka2_1:8,P00552,1.00097,NO,117,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.828,-0.828,,,,H,A,1.04,-0.78,0.755,,45.83,HHA,-1.79333,0.100394,0.00282984,1.00097 kka2_1:8_A119A,kka2_1:8_119,Kka2,kka2_1:8,P00552,1.00097,NO,119,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.073,-1.073,,,0.019,H,A,0.46,-0.57,1.511,,71.59,AHH,-2.34,0.100394,0.00441074,1.00097 kka2_1:8_A119A,kka2_1:8_119,Kka2,kka2_1:8,P00552,1.00097,NO,119,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.073,-1.073,,,0.019,H,A,0.46,-0.57,1.511,,71.59,AHH,-2.34,0.100394,0.00441074,1.00097 beta-lactamase_625_S96L,beta-lactamase_625_96,TEM-1,beta-lactamase_625,P62593,1.00098,NO,96,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.27,-3.527,1.257,,0.368,,b,0.27,0.39,5.244,,73.78,HPP,-2.019,0.213352,0.00551835,1.00098 kka2_1:4_L260L,kka2_1:4_260,Kka2,kka2_1:4,P00552,1.00098,NO,260,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.741,-0.741,,,0.022,H,A,0.55,-0.52,,,,HHA,-0.845667,0.168804,0.0233782,1.00098 kka2_1:8_F264F,kka2_1:8_264,Kka2,kka2_1:8,P00552,1.00098,NO,264,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.02,-1.02,,,0.296,,?,1.62,0.02,1.553,,71.59,HHO,-0.9655,0.100394,,1.00098 kka2_1:8_F264F,kka2_1:8_264,Kka2,kka2_1:8,P00552,1.00098,NO,264,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.02,-1.02,,,0.296,,?,1.62,0.02,1.553,,71.59,HHO,-0.9655,0.100394,,1.00098 beta-lactamase_625_L136V,beta-lactamase_625_136,TEM-1,beta-lactamase_625,P62593,1.00099,NO,136,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.232,-1.932,0.7,,,H,A,0.55,-0.34,0.336,,48.95,HHH,-1.088,0.213352,0.00442304,1.00099 beta-lactamase_625_N173P,beta-lactamase_625_173,TEM-1,beta-lactamase_625,P62593,1.00099,NO,173,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-2.663,-3.891,1.228,,1.044,T,l,0.61,1.25,1.426,,77.62,OPA,-1.46633,0.213352,0.0033769,1.00099 kka2_1:4_M197M,kka2_1:4_197,Kka2,kka2_1:4,P00552,1.00099,NO,197,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.707,-1.707,,,0.121,E,B,0.55,-1.19,0.415,,65.53,HHH,-1.847,0.168804,0.00921295,1.00099 Pab1_Q194G,Pab1_194,Pab1,Pab1,P04147,1.00099,NO,194,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.179,-3.409,1.23,,,,,,,,,,OPA,-1.59767,0.175299,0.0016145,1.00099 beta-lactamase_39_T187C,beta-lactamase_39_187,TEM-1,beta-lactamase_39,P62593,1.001,NO,187,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.401,-4.859,3.458,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.0495842,0.00491782,1.001 beta-lactamase_625_L135T,beta-lactamase_625_135,TEM-1,beta-lactamase_625,P62593,1.001,NO,135,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.002,-3.475,2.473,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.213352,0.00244423,1.001 beta-lactamase_625_P217E,beta-lactamase_625_217,TEM-1,beta-lactamase_625,P62593,1.001,NO,217,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-2.062,-2.651,0.589,,0.496,I,A,0.52,-0.33,1.087,,74.48,OOH,-1.64333,0.213352,0.00463211,1.001 beta-lactamase_39_M270A,beta-lactamase_39_270,TEM-1,beta-lactamase_39,P62593,1.00101,NO,270,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.0495842,0.00767762,1.00101 beta-lactamase_625_P255G,beta-lactamase_625_255,TEM-1,beta-lactamase_625,P62593,1.00101,NO,255,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.213352,0.00499612,1.00101 kka2_1:2_V153C,kka2_1:2_153,Kka2,kka2_1:2,P00552,1.00101,NO,153,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.092,-4.724,3.632,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.295029,0.00501119,1.00101 kka2_1:4_A215A,kka2_1:4_215,Kka2,kka2_1:4,P00552,1.00101,NO,215,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.968,-0.968,,,0.039,E,B,0.46,-0.59,0.754,,50.38,HHA,-1.00467,0.168804,0.00529129,1.00101 kka2_1:4_I115I,kka2_1:4_115,Kka2,kka2_1:4,P00552,1.00101,NO,115,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.606,-1.606,,,0.105,H,A,1.52,-1.18,9.996,9.996,65.53,PHH,-2.205,0.168804,0.00836567,1.00101 beta-lactamase_156_Q37S,beta-lactamase_156_37,TEM-1,beta-lactamase_156,P62593,1.00102,NO,37,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.134,-2.839,0.705,,0.613,H,A,0.64,1.98,12.052,12.052,73.08,APH,-2.06967,0.111618,0.00425833,1.00102 beta-lactamase_156_T138V,beta-lactamase_156_138,TEM-1,beta-lactamase_156,P62593,1.00102,NO,138,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.506,-3.689,1.183,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.111618,0.00487868,1.00102 beta-lactamase_625_G141Q,beta-lactamase_625_141,TEM-1,beta-lactamase_625,P62593,1.00102,NO,141,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.828,-3.982,3.154,,0.575,T,l,0.29,-0.28,0.198,,64.69,HOO,-1.08933,0.213352,0.0012419,1.00102 beta-lactamase_E175W,beta-lactamase_175,TEM-1,beta-lactamase,P62593,1.00102,NO,175,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.336,-5.537,3.201,6.0311,0.551,,A,0.75,1.05,5.316,,77.62,AAB,-1.31233,0.221079,0.00482205,1.00102 kka2_1:8_A144A,kka2_1:8_144,Kka2,kka2_1:8,P00552,1.00102,NO,144,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.859,-0.859,,,,H,A,1.04,0.21,1.118,,52.65,BHB,-1.72933,0.100394,0.00231095,1.00102 kka2_1:8_A144A,kka2_1:8_144,Kka2,kka2_1:8,P00552,1.00102,NO,144,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.859,-0.859,,,,H,A,1.04,0.21,1.118,,52.65,BHB,-1.72933,0.100394,0.00231095,1.00102 kka2_1:8_A222A,kka2_1:8_222,Kka2,kka2_1:8,P00552,1.00102,NO,222,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.725,-0.725,,,,H,A,1.04,-1.21,,,,HHH,-1.10833,0.100394,0.00207657,1.00102 kka2_1:8_A222A,kka2_1:8_222,Kka2,kka2_1:8,P00552,1.00102,NO,222,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.725,-0.725,,,,H,A,1.04,-1.21,,,,HHH,-1.10833,0.100394,0.00207657,1.00102 kka2_1:8_W236W,kka2_1:8_236,Kka2,kka2_1:8,P00552,1.00102,NO,236,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-1.363,-1.363,,,0.303,H,A,1.51,-0.76,1.87,,48.48,AHH,-1.81267,0.100394,0.0088796,1.00102 kka2_1:8_W236W,kka2_1:8_236,Kka2,kka2_1:8,P00552,1.00102,NO,236,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-1.363,-1.363,,,0.303,H,A,1.51,-0.76,1.87,,48.48,AHH,-1.81267,0.100394,0.0088796,1.00102 beta-lactamase_0_L74I,beta-lactamase_0_74,TEM-1,beta-lactamase_0,P62593,1.00103,NO,74,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.296,-2.577,1.281,,,H,A,0.55,-0.91,1.46,,50,HHO,-1.34933,0.0500837,0.00493255,1.00103 beta-lactamase_156_L100N,beta-lactamase_156_100,TEM-1,beta-lactamase_156,P62593,1.00103,NO,100,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.218,-4.207,2.989,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.111618,0.00413885,1.00103 beta-lactamase_39_G114Q,beta-lactamase_39_114,TEM-1,beta-lactamase_39,P62593,1.00103,NO,114,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.094,-4.039,2.945,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.0495842,0.00224919,1.00103 kka2_1:1_V75V,kka2_1:1_75,Kka2,kka2_1:1,P00552,1.00103,NO,75,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-2.06,-2.06,,,0.042,.,B,0.44,-0.2,2.815,,71.59,OHO,-1.563,0.520039,0.00693733,1.00103 kka2_1:2_G233G,kka2_1:2_233,Kka2,kka2_1:2,P00552,1.00103,NO,233,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.748,-0.748,,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.295029,0.00232366,1.00103 kka2_1:4_A144A,kka2_1:4_144,Kka2,kka2_1:4,P00552,1.00103,NO,144,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.859,-0.859,,,,H,A,0.46,0.21,6.844,,52.65,BHB,-1.72933,0.168804,0.00231095,1.00103 kka2_1:4_Y257Y,kka2_1:4_257,Kka2,kka2_1:4,P00552,1.00103,NO,257,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-1.064,-1.064,,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.168804,0.0148191,1.00103 kka2_1:8_Y257Y,kka2_1:8_257,Kka2,kka2_1:8,P00552,1.00103,NO,257,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-1.064,-1.064,,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.100394,0.0148191,1.00103 kka2_1:8_Y257Y,kka2_1:8_257,Kka2,kka2_1:8,P00552,1.00103,NO,257,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-1.064,-1.064,,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.100394,0.0148191,1.00103 beta-lactamase_156_D271M,beta-lactamase_156_271,TEM-1,beta-lactamase_156,P62593,1.00104,NO,271,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.111618,0.00752082,1.00104 beta-lactamase_156_K109M,beta-lactamase_156_109,TEM-1,beta-lactamase_156,P62593,1.00104,NO,109,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.734,-4.742,3.008,,0.787,G,A,2.34,2.21,6.031,,72.73,ABB,-1.63333,0.111618,0.00462493,1.00104 beta-lactamase_156_V29E,beta-lactamase_156_29,TEM-1,beta-lactamase_156,P62593,1.00104,NO,29,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-2.856,-1.855,-1.001,,0.733,H,A,0.44,-0.78,3.685,,93.01,HHB,-2.24733,0.111618,0.00318969,1.00104 beta-lactamase_39_K30A,beta-lactamase_39_30,TEM-1,beta-lactamase_39,P62593,1.00104,NO,30,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-2.307,-2.101,-0.206,,0.142,H,A,2.34,-0.65,6.717,,93.01,HBH,-2.32833,0.0495842,0.00448593,1.00104 beta-lactamase_625_S96M,beta-lactamase_625_96,TEM-1,beta-lactamase_625,P62593,1.00104,NO,96,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.27,-3.49,1.22,,0.368,,b,0.27,0.39,5.244,,73.78,HPP,-2.019,0.213352,0.00551835,1.00104 beta-lactamase_156_R159G,beta-lactamase_156_159,TEM-1,beta-lactamase_156,P62593,1.00105,NO,159,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-0.94,-3.384,2.444,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.111618,0.00108472,1.00105 beta-lactamase_39_L55C,beta-lactamase_39_55,TEM-1,beta-lactamase_39,P62593,1.00105,NO,55,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.86,-4.909,3.049,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.0495842,0.00403741,1.00105 beta-lactamase_625_T263L,beta-lactamase_625_263,TEM-1,beta-lactamase_625,P62593,1.00105,NO,263,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.213352,0.0110582,1.00105 kka2_1:2_D190D,kka2_1:2_190,Kka2,kka2_1:2,P00552,1.00105,NO,190,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.708,-0.708,,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.295029,0.00247989,1.00105 kka2_1:2_V185V,kka2_1:2_185,Kka2,kka2_1:2,P00552,1.00105,NO,185,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.045,-1.045,,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.295029,0.00367031,1.00105 kka2_1:8_F240F,kka2_1:8_240,Kka2,kka2_1:8,P00552,1.00105,NO,240,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-0.911,-0.911,,,,H,A,1.62,-1.21,0.697,,50.38,BHH,-1.67267,0.100394,0.00552543,1.00105 kka2_1:8_F240F,kka2_1:8_240,Kka2,kka2_1:8,P00552,1.00105,NO,240,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-0.911,-0.911,,,,H,A,1.62,-1.21,0.697,,50.38,BHH,-1.67267,0.100394,0.00552543,1.00105 beta-lactamase_156_A77G,beta-lactamase_156_77,TEM-1,beta-lactamase_156,P62593,1.00106,NO,77,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.234,-2.31,1.076,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.111618,0.00282362,1.00106 beta-lactamase_156_K213V,beta-lactamase_156_213,TEM-1,beta-lactamase_156,P62593,1.00107,NO,213,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.81,-3.705,1.895,,0.67,,A,2.34,0.29,3.924,,67.83,ABH,-1.57767,0.111618,0.00610411,1.00107 beta-lactamase_2500_T138M,beta-lactamase_2500_138,TEM-1,beta-lactamase_2500,P62593,1.00107,NO,138,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.506,-4.821,2.315,,0.662,H,A,0.22,-0.03,30.445,30.445,73.78,HPP,-1.81233,0.361275,0.00487868,1.00107 kka2_1:4_L232L,kka2_1:4_232,Kka2,kka2_1:4,P00552,1.00107,NO,232,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.514,-1.514,,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.168804,0.00800103,1.00107 kka2_1:8_D157A,kka2_1:8_157,Kka2,kka2_1:8,P00552,1.00108,NO,157,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.993,-3.298,2.305,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.100394,0.0042313,1.00108 kka2_1:8_D157A,kka2_1:8_157,Kka2,kka2_1:8,P00552,1.00108,NO,157,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.993,-3.298,2.305,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.100394,0.0042313,1.00108 kka2_1:8_E262E,kka2_1:8_262,Kka2,kka2_1:8,P00552,1.00108,NO,262,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-0.829,-0.829,,,0.059,G,A,1.52,-0.18,0.837,,42.42,AAH,-0.816,0.100394,0.0191586,1.00108 kka2_1:8_E262E,kka2_1:8_262,Kka2,kka2_1:8,P00552,1.00108,NO,262,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-0.829,-0.829,,,0.059,G,A,1.52,-0.18,0.837,,42.42,AAH,-0.816,0.100394,0.0191586,1.00108 kka2_1:8_V113V,kka2_1:8_113,Kka2,kka2_1:8,P00552,1.00108,NO,113,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.233,-1.233,,,0.008,H,A,1.48,-1.17,1.254,,52.27,BHP,-2.08367,0.100394,0.00650191,1.00108 kka2_1:8_V113V,kka2_1:8_113,Kka2,kka2_1:8,P00552,1.00108,NO,113,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.233,-1.233,,,0.008,H,A,1.48,-1.17,1.254,,52.27,BHP,-2.08367,0.100394,0.00650191,1.00108 beta-lactamase_156_E238A,beta-lactamase_156_238,TEM-1,beta-lactamase_156,P62593,1.00109,NO,238,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.111618,0.00743256,1.00109 beta-lactamase_2500_A77M,beta-lactamase_2500_77,TEM-1,beta-lactamase_2500,P62593,1.00109,NO,77,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.234,-4.524,3.29,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.361275,0.00282362,1.00109 beta-lactamase_625_V157G,beta-lactamase_625_157,TEM-1,beta-lactamase_625,P62593,1.00109,NO,157,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.751,-3.625,1.874,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.213352,0.00506849,1.00109 kka2_1:4_F240F,kka2_1:4_240,Kka2,kka2_1:4,P00552,1.00109,NO,240,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-0.911,-0.911,,,,H,A,0.58,-1.21,5.798,,50.38,BHH,-1.67267,0.168804,0.00552543,1.00109 kka2_1:4_W236W,kka2_1:4_236,Kka2,kka2_1:4,P00552,1.00109,NO,236,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-1.363,-1.363,,,0.303,H,A,0.47,-0.76,2.277,,48.48,AHH,-1.81267,0.168804,0.0088796,1.00109 beta-lactamase_156_V31T,beta-lactamase_156_31,TEM-1,beta-lactamase_156,P62593,1.0011,NO,31,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.822,-2.805,0.983,,,H,A,0.44,-0.46,4.126,,73.78,BHB,-2.03767,0.111618,0.00478065,1.0011 beta-lactamase_2500_A34M,beta-lactamase_2500_34,TEM-1,beta-lactamase_2500,P62593,1.0011,NO,34,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.059,-4.351,2.292,,,H,A,0.46,-0.54,2.921,,73.78,AHA,-1.74967,0.361275,0.00407913,1.0011 beta-lactamase_2500_E166M,beta-lactamase_2500_166,TEM-1,beta-lactamase_2500,P62593,1.0011,NO,166,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.756,-4.707,2.951,,0.508,G,A,1.04,1.05,2.124,,73.08,OAH,-1.42233,0.361275,0.00512989,1.0011 beta-lactamase_39_L192V,beta-lactamase_39_192,TEM-1,beta-lactamase_39,P62593,1.0011,NO,192,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.254,-1.986,0.732,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.0495842,0.00558728,1.0011 beta-lactamase_625_R275N,beta-lactamase_625_275,TEM-1,beta-lactamase_625,P62593,1.0011,NO,275,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.213352,0.0141984,1.0011 kka2_1:8_E142V,kka2_1:8_142,Kka2,kka2_1:8,P00552,1.0011,NO,142,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.221,-3.677,1.456,,0.471,H,A,1.04,0.85,2.655,,65.53,HAB,-2.08033,0.100394,0.00748883,1.0011 kka2_1:8_E142V,kka2_1:8_142,Kka2,kka2_1:8,P00552,1.0011,NO,142,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.221,-3.677,1.456,,0.471,H,A,1.04,0.85,2.655,,65.53,HAB,-2.08033,0.100394,0.00748883,1.0011 kka2_1:8_I228I,kka2_1:8_228,Kka2,kka2_1:8,P00552,1.0011,NO,228,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.142,-1.142,,,,H,A,1.52,-1.2,1.521,,71.59,AHH,-1.54633,0.100394,0.00458834,1.0011 kka2_1:8_I228I,kka2_1:8_228,Kka2,kka2_1:8,P00552,1.0011,NO,228,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.142,-1.142,,,,H,A,1.52,-1.2,1.521,,71.59,AHH,-1.54633,0.100394,0.00458834,1.0011 beta-lactamase_156_G236N,beta-lactamase_156_236,TEM-1,beta-lactamase_156,P62593,1.00111,NO,236,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.784,-3.509,2.725,,0.241,,b,0.29,-0.59,1.883,,64.69,HOO,-1.025,0.111618,0.00162372,1.00111 beta-lactamase_39_P25L,beta-lactamase_39_25,TEM-1,beta-lactamase_39,P62593,1.00111,NO,25,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.526,-3.586,2.06,,0.624,H,A,0.52,0.14,1.157,,73.08,BOA,-2.15367,0.0495842,0.00347571,1.00111 beta-lactamase_625_Q97C,beta-lactamase_625_97,TEM-1,beta-lactamase_625,P62593,1.00111,NO,97,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.072,-5.163,3.091,,0.823,G,A,0.64,2.42,16.954,16.954,77.62,PPP,-2.43833,0.213352,0.0045116,1.00111 kka2_1:4_A117A,kka2_1:4_117,Kka2,kka2_1:4,P00552,1.00111,NO,117,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.828,-0.828,,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.168804,0.00282984,1.00111 beta-lactamase_156_D207W,beta-lactamase_156_207,TEM-1,beta-lactamase_156,P62593,1.00112,NO,207,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.064,-5.493,3.429,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.111618,0.00592942,1.00112 beta-lactamase_2500_S96R,beta-lactamase_2500_96,TEM-1,beta-lactamase_2500,P62593,1.00112,NO,96,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.27,-2.133,-0.137,,0.368,,b,0.27,0.39,32.348,32.348,73.78,HPP,-2.019,0.361275,0.00551835,1.00112 beta-lactamase_39_P165D,beta-lactamase_39_165,TEM-1,beta-lactamase_39,P62593,1.00112,NO,165,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.373,-3.54,2.167,,0.203,T,A,0.52,-0.31,3.907,,73.78,AOA,-1.359,0.0495842,0.00549538,1.00112 beta-lactamase_625_L47A,beta-lactamase_625_47,TEM-1,beta-lactamase_625,P62593,1.00112,NO,47,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.876,-3.301,1.425,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.213352,0.00439844,1.00112 gb1_T279W,gb1_279,gb1,gb1,P06654,1.00112,NO,279,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.32,-4.997,3.677,,,,,,,0.529,,35.71,HPH,-1.50067,0.177985,0.00421454,1.00112 kka2_1:4_A119A,kka2_1:4_119,Kka2,kka2_1:4,P00552,1.00112,NO,119,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.073,-1.073,,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.168804,0.00441074,1.00112 kka2_1:4_C131C,kka2_1:4_131,Kka2,kka2_1:4,P00552,1.00112,NO,131,C,C,CC,Special,Special,5.07,5.07,0,0,121,121,0,108.5,108.5,0,-0.831,-0.831,,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.168804,0.00170814,1.00112 kka2_1:4_F263F,kka2_1:4_263,Kka2,kka2_1:4,P00552,1.00112,NO,263,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-0.911,-0.911,,,0.006,G,A,0.58,-0.12,2.284,,45.83,AHH,-0.92,0.168804,0.0172454,1.00112 kka2_1:4_I228I,kka2_1:4_228,Kka2,kka2_1:4,P00552,1.00112,NO,228,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.142,-1.142,,,,H,A,0.48,-1.2,1.292,,71.59,AHH,-1.54633,0.168804,0.00458834,1.00112 kka2_1:8_T187T,kka2_1:8_187,Kka2,kka2_1:8,P00552,1.00112,NO,187,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.273,-1.273,,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.100394,0.00693073,1.00112 kka2_1:8_T187T,kka2_1:8_187,Kka2,kka2_1:8,P00552,1.00112,NO,187,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.273,-1.273,,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.100394,0.00693073,1.00112 beta-lactamase_156_K109D,beta-lactamase_156_109,TEM-1,beta-lactamase_156,P62593,1.00113,NO,109,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.734,-2.919,1.185,,0.787,G,A,2.34,2.21,6.031,,72.73,ABB,-1.63333,0.111618,0.00462493,1.00113 beta-lactamase_156_K190D,beta-lactamase_156_190,TEM-1,beta-lactamase_156,P62593,1.00113,NO,190,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.994,-3.691,1.697,,0.371,H,A,2.34,0.16,1.513,,77.62,BBH,-1.64167,0.111618,0.00574527,1.00113 beta-lactamase_156_N50L,beta-lactamase_156_50,TEM-1,beta-lactamase_156,P62593,1.00113,NO,50,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-2.979,-2.892,-0.087,,0.912,T,A,0.61,1.24,13.295,13.295,77.62,HPP,-2.134,0.111618,0.0047211,1.00113 beta-lactamase_39_D174V,beta-lactamase_39_174,TEM-1,beta-lactamase_39,P62593,1.00113,NO,174,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.738,-3.754,3.016,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.0495842,0.00125633,1.00113 beta-lactamase_625_L49T,beta-lactamase_625_49,TEM-1,beta-lactamase_625,P62593,1.00113,NO,49,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.897,-1.853,-0.044,,0.131,T,A,0.55,0.04,3.112,,64.69,AHP,-1.99233,0.213352,0.00401477,1.00113 beta-lactamase_625_S266C,beta-lactamase_625_266,TEM-1,beta-lactamase_625,P62593,1.00113,NO,266,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.213352,0.0140785,1.00113 kka2_1:4_R211R,kka2_1:4_211,Kka2,kka2_1:4,P00552,1.00113,NO,211,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-0.899,-0.899,,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.168804,0.00204888,1.00113 PSD95pdz3_P346G,PSD95pdz3_346,PSD95pdz3,PSD95pdz3,P31016,1.00113,NO,346,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.236,-3.04,1.804,5.02406,,,,,14.6629,,,,OOH,-1.18367,0.0758425,0.000758563,1.00113 kka2_1:2_V186V,kka2_1:2_186,Kka2,kka2_1:2,P00552,1.00114,NO,186,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.011,-1.011,,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.295029,0.00409703,1.00114 kka2_1:4_G99G,kka2_1:4_99,Kka2,kka2_1:4,P00552,1.00114,NO,99,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.596,-0.596,,,0.368,S,g,0.29,-0.87,,,,OOP,-1.63067,0.168804,0.00186055,1.00114 kka2_1:4_V113V,kka2_1:4_113,Kka2,kka2_1:4,P00552,1.00114,NO,113,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.233,-1.233,,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.168804,0.00650191,1.00114 beta-lactamase_156_A182P,beta-lactamase_156_182,TEM-1,beta-lactamase_156,P62593,1.00115,NO,182,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.777,-3.952,2.175,,0.136,H,A,0.46,-0.66,16.784,16.784,93.01,OHH,-1.27367,0.111618,0.00559099,1.00115 beta-lactamase_156_A183F,beta-lactamase_156_183,TEM-1,beta-lactamase_156,P62593,1.00115,NO,183,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.231,-4.164,2.933,,0.155,H,A,0.46,-0.91,23.859,23.859,77.62,HHH,-1.53367,0.111618,0.00296631,1.00115 beta-lactamase_156_E35R,beta-lactamase_156_35,TEM-1,beta-lactamase_156,P62593,1.00115,NO,35,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-0.869,-3.551,2.682,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.111618,0.00174441,1.00115 beta-lactamase_E61T,beta-lactamase_61,TEM-1,beta-lactamase,P62593,1.00115,NO,61,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.115,-3.52,1.405,6.29701,0.775,T,a,0.52,1.29,1.975,,77.62,OAA,-1.92567,0.221079,0.00440955,1.00115 kka2_1:2_G189G,kka2_1:2_189,Kka2,kka2_1:2,P00552,1.00115,NO,189,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.596,-0.596,,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.295029,0.00253688,1.00115 kka2_1:8_C131C,kka2_1:8_131,Kka2,kka2_1:8,P00552,1.00115,NO,131,C,C,CC,Special,Special,5.07,5.07,0,0,121,121,0,108.5,108.5,0,-0.831,-0.831,,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.100394,0.00170814,1.00115 kka2_1:8_C131C,kka2_1:8_131,Kka2,kka2_1:8,P00552,1.00115,NO,131,C,C,CC,Special,Special,5.07,5.07,0,0,121,121,0,108.5,108.5,0,-0.831,-0.831,,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.100394,0.00170814,1.00115 kka2_1:8_D216D,kka2_1:8_216,Kka2,kka2_1:8,P00552,1.00115,NO,216,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.785,-0.785,,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.100394,0.00229969,1.00115 kka2_1:8_D216D,kka2_1:8_216,Kka2,kka2_1:8,P00552,1.00115,NO,216,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.785,-0.785,,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.100394,0.00229969,1.00115 kka2_1:8_F263F,kka2_1:8_263,Kka2,kka2_1:8,P00552,1.00115,NO,263,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-0.911,-0.911,,,0.006,G,A,1.62,-0.12,0.928,,45.83,AHH,-0.92,0.100394,0.0172454,1.00115 kka2_1:8_F263F,kka2_1:8_263,Kka2,kka2_1:8,P00552,1.00115,NO,263,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-0.911,-0.911,,,0.006,G,A,1.62,-0.12,0.928,,45.83,AHH,-0.92,0.100394,0.0172454,1.00115 beta-lactamase_156_V260L,beta-lactamase_156_260,TEM-1,beta-lactamase_156,P62593,1.00116,NO,260,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.111618,0.00471757,1.00116 beta-lactamase_39_K286V,beta-lactamase_39_286,TEM-1,beta-lactamase_39,P62593,1.00116,NO,286,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.0495842,,1.00116 beta-lactamase_39_L38R,beta-lactamase_39_38,TEM-1,beta-lactamase_39,P62593,1.00116,NO,38,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.343,-4.054,2.711,,0.088,H,A,0.55,0.2,17.089,17.089,64.34,PHO,-1.78033,0.0495842,0.00373244,1.00116 beta-lactamase_625_L199F,beta-lactamase_625_199,TEM-1,beta-lactamase_625,P62593,1.00116,NO,199,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-2.942,-4.403,1.461,,0.832,H,A,0.55,0.42,1.552,,77.62,PHH,-2.32933,0.213352,0.0048649,1.00116 kka2_1:1_R173R,kka2_1:1_173,Kka2,kka2_1:1,P00552,1.00116,NO,173,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.407,-2.407,,,0.308,H,A,0.16,-0.13,14.756,14.756,65.53,HBH,-1.70533,0.520039,0.00784999,1.00116 kka2_1:2_G213G,kka2_1:2_213,Kka2,kka2_1:2,P00552,1.00116,NO,213,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.596,-0.596,,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.295029,0.00187654,1.00116 kka2_1:8_N195N,kka2_1:8_195,Kka2,kka2_1:8,P00552,1.00116,NO,195,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-0.836,-0.836,,,0.037,G,A,0.43,-1.36,1.108,,48.11,OPH,-1.26567,0.100394,0.00276134,1.00116 kka2_1:8_N195N,kka2_1:8_195,Kka2,kka2_1:8,P00552,1.00116,NO,195,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-0.836,-0.836,,,0.037,G,A,0.43,-1.36,1.108,,48.11,OPH,-1.26567,0.100394,0.00276134,1.00116 kka2_1:8_R211R,kka2_1:8_211,Kka2,kka2_1:8,P00552,1.00116,NO,211,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-0.899,-0.899,,,0.12,T,a,0.16,-0.39,0.615,,49.62,OBH,-0.966,0.100394,0.00204888,1.00116 kka2_1:8_R211R,kka2_1:8_211,Kka2,kka2_1:8,P00552,1.00116,NO,211,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-0.899,-0.899,,,0.12,T,a,0.16,-0.39,0.615,,49.62,OBH,-0.966,0.100394,0.00204888,1.00116 kka2_1:8_R217R,kka2_1:8_217,Kka2,kka2_1:8,P00552,1.00116,NO,217,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.158,-1.158,,,0.252,T,A,0.16,-0.59,1.151,,52.27,ABH,-1.127,0.100394,0.0047191,1.00116 kka2_1:8_R217R,kka2_1:8_217,Kka2,kka2_1:8,P00552,1.00116,NO,217,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.158,-1.158,,,0.252,T,A,0.16,-0.59,1.151,,52.27,ABH,-1.127,0.100394,0.0047191,1.00116 beta-lactamase_156_Q97P,beta-lactamase_156_97,TEM-1,beta-lactamase_156,P62593,1.00117,NO,97,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.072,-2.583,0.511,,0.823,G,A,0.64,2.42,4.457,,77.62,PPP,-2.43833,0.111618,0.0045116,1.00117 beta-lactamase_625_A200P,beta-lactamase_625_200,TEM-1,beta-lactamase_625,P62593,1.00117,NO,200,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.878,-2.581,0.703,,0.757,H,A,0.46,-0.19,12.672,12.672,77.62,HHP,-2.001,0.213352,0.0060056,1.00117 beta-lactamase_625_D36T,beta-lactamase_625_36,TEM-1,beta-lactamase_625,P62593,1.00117,NO,36,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.732,-2.57,-0.162,,0.555,H,A,0.75,1.17,2.26,,77.62,AAP,-1.91167,0.213352,0.00476483,1.00117 beta-lactamase_0_S201W,beta-lactamase_0_201,TEM-1,beta-lactamase_0,P62593,1.00118,NO,201,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.183,-5.344,4.161,,0.064,H,A,0.27,-0.07,3.54,,64.69,HPB,-1.451,0.0500837,0.00198815,1.00118 beta-lactamase_156_K190T,beta-lactamase_156_190,TEM-1,beta-lactamase_156,P62593,1.00118,NO,190,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.994,-2.389,0.395,,0.371,H,A,2.34,0.16,1.513,,77.62,BBH,-1.64167,0.111618,0.00574527,1.00118 beta-lactamase_625_E102D,beta-lactamase_625_102,TEM-1,beta-lactamase_625,P62593,1.00118,NO,102,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.118,-2.118,0,,0.722,S,B,1.04,1.82,1.336,,73.08,HAH,-1.581,0.213352,0.00486633,1.00118 beta-lactamase_625_M180D,beta-lactamase_625_180,TEM-1,beta-lactamase_625,P62593,1.00118,NO,180,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-2.795,-3.594,0.799,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.213352,0.00552048,1.00118 beta-lactamase_L167V,beta-lactamase_167,TEM-1,beta-lactamase,P62593,1.00118,NO,167,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.138,-2.277,1.139,5.13111,0.015,G,A,0.08,-0.63,0.4,,64.69,AHP,-1.30767,0.221079,0.00303566,1.00118 beta-lactamase_156_A185V,beta-lactamase_156_185,TEM-1,beta-lactamase_156,P62593,1.00119,NO,185,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.406,-2.093,0.687,,,H,A,0.46,-1.02,0.365,,65.03,HHP,-1.84033,0.111618,0.00467449,1.00119 beta-lactamase_2500_E195T,beta-lactamase_2500_195,TEM-1,beta-lactamase_2500,P62593,1.00119,NO,195,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.186,-2.956,0.77,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.361275,0.00496565,1.00119 kka2_1:4_D216D,kka2_1:4_216,Kka2,kka2_1:4,P00552,1.00119,NO,216,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.785,-0.785,,,0.018,E,B,0.75,-0.51,0.112,,19.32,HAB,-0.970333,0.168804,0.00229969,1.00119 beta-lactamase_156_E272T,beta-lactamase_156_272,TEM-1,beta-lactamase_156,P62593,1.0012,NO,272,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.111618,0.00545371,1.0012 beta-lactamase_156_N50I,beta-lactamase_156_50,TEM-1,beta-lactamase_156,P62593,1.0012,NO,50,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-2.979,-3.889,0.91,,0.912,T,A,0.61,1.24,13.295,13.295,77.62,HPP,-2.134,0.111618,0.0047211,1.0012 kka2_1:8_D261D,kka2_1:8_261,Kka2,kka2_1:8,P00552,1.0012,NO,261,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.708,-0.708,,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.100394,0.0224846,1.0012 kka2_1:8_D261D,kka2_1:8_261,Kka2,kka2_1:8,P00552,1.0012,NO,261,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.708,-0.708,,,0.146,G,A,0.29,-0.33,,,,HAA,-0.759333,0.100394,0.0224846,1.0012 kka2_1:8_L93V,kka2_1:8_93,Kka2,kka2_1:8,P00552,1.0012,NO,93,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.815,-2.967,2.152,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.100394,0.00131498,1.0012 kka2_1:8_L93V,kka2_1:8_93,Kka2,kka2_1:8,P00552,1.0012,NO,93,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.815,-2.967,2.152,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.100394,0.00131498,1.0012 beta-lactamase_0_M153K,beta-lactamase_0_153,TEM-1,beta-lactamase_0,P62593,1.00121,NO,153,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-3.193,-3.777,0.584,,0.14,T,A,0.55,-0.11,3.826,,77.62,PHO,-2.25767,0.0500837,0.00509109,1.00121 beta-lactamase_M153I,beta-lactamase_153,TEM-1,beta-lactamase,P62593,1.00121,NO,153,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-3.193,-1.739,-1.454,5.46509,0.14,T,A,1.07,-0.11,2.061,,77.62,PHO,-2.25767,0.221079,0.00509109,1.00121 kka2_1:4_D261D,kka2_1:4_261,Kka2,kka2_1:4,P00552,1.00121,NO,261,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.708,-0.708,,,0.146,G,A,0.75,-0.33,,,,HAA,-0.759333,0.168804,0.0224846,1.00121 kka2_1:4_L241L,kka2_1:4_241,Kka2,kka2_1:4,P00552,1.00121,NO,241,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.158,-1.158,,,0.08,H,A,0.55,-0.82,1.598,,63.26,HHH,-1.58533,0.168804,0.0117299,1.00121 beta-lactamase_2500_D207E,beta-lactamase_2500_207,TEM-1,beta-lactamase_2500,P62593,1.00122,NO,207,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.064,-2.615,0.551,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.361275,0.00592942,1.00122 beta-lactamase_39_G76C,beta-lactamase_39_76,TEM-1,beta-lactamase_39,P62593,1.00122,NO,76,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.189,-4.823,3.634,,,H,A,0.29,-0.67,2.145,,67.83,OOH,-1.22267,0.0495842,0.00476637,1.00122 PSD95pdz3_L342V,PSD95pdz3_342,PSD95pdz3,PSD95pdz3,P31016,1.00122,NO,342,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.347,-2.535,1.188,5.03015,,,,,12.0762,,,,HHH,-1.428,0.0758425,0.00081112,1.00122 beta-lactamase_156_I206A,beta-lactamase_156_206,TEM-1,beta-lactamase_156,P62593,1.00123,NO,206,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-2.429,-2.387,-0.042,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.111618,0.00528934,1.00123 beta-lactamase_156_I206L,beta-lactamase_156_206,TEM-1,beta-lactamase_156,P62593,1.00124,NO,206,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-2.429,-2.261,-0.168,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.111618,0.00528934,1.00124 beta-lactamase_39_S283M,beta-lactamase_39_283,TEM-1,beta-lactamase_39,P62593,1.00124,NO,283,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.0495842,0.0429138,1.00124 beta-lactamase_625_H110F,beta-lactamase_625_110,TEM-1,beta-lactamase_625,P62593,1.00124,NO,110,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-1.706,-4.019,2.313,,0.341,G,a,0.17,1.08,31.31,31.31,64.69,BBH,-1.73333,0.213352,0.00441499,1.00124 beta-lactamase_625_R273H,beta-lactamase_625_273,TEM-1,beta-lactamase_625,P62593,1.00124,NO,273,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.314,-4.599,2.285,,0.564,H,A,1.2,1.57,1.455,,73.78,ABP,-1.841,0.213352,0.0077952,1.00124 kka2_1:2_C77C,kka2_1:2_77,Kka2,kka2_1:2,P00552,1.00124,NO,77,C,C,CC,Special,Special,5.07,5.07,0,0,121,121,0,108.5,108.5,0,-1.477,-1.477,,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.295029,0.00441216,1.00124 beta-lactamase_156_L150F,beta-lactamase_156_150,TEM-1,beta-lactamase_156,P62593,1.00125,NO,150,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.326,-3.884,2.558,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.111618,0.00463171,1.00125 beta-lactamase_156_L219V,beta-lactamase_156_219,TEM-1,beta-lactamase_156,P62593,1.00125,NO,219,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.313,-2.847,1.534,,,I,A,0.55,-0.51,2.321,,74.48,HHB,-1.21533,0.111618,0.00664345,1.00125 beta-lactamase_156_R275K,beta-lactamase_156_275,TEM-1,beta-lactamase_156,P62593,1.00125,NO,275,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.111618,0.0141984,1.00125 beta-lactamase_2500_V157Y,beta-lactamase_2500_157,TEM-1,beta-lactamase_2500,P62593,1.00125,NO,157,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.751,-2.838,1.087,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.361275,0.00506849,1.00125 beta-lactamase_39_A40E,beta-lactamase_39_40,TEM-1,beta-lactamase_39,P62593,1.00125,NO,40,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.402,-3.641,2.239,,0.155,S,B,0.46,0.21,0.783,,73.78,OHB,-1.40267,0.0495842,0.00490026,1.00125 beta-lactamase_39_K254I,beta-lactamase_39_254,TEM-1,beta-lactamase_39,P62593,1.00125,NO,254,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.0495842,0.00369,1.00125 beta-lactamase_39_R202G,beta-lactamase_39_202,TEM-1,beta-lactamase_39,P62593,1.00126,NO,202,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.292,-3.349,2.057,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.0495842,0.00321899,1.00126 beta-lactamase_625_D271A,beta-lactamase_625_271,TEM-1,beta-lactamase_625,P62593,1.00126,NO,271,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.213352,0.00752082,1.00126 beta-lactamase_625_K144Q,beta-lactamase_625_144,TEM-1,beta-lactamase_625,P62593,1.00126,NO,144,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-2.388,-2.378,-0.01,,0.863,H,A,2.34,1.27,2.313,,77.62,OBA,-1.904,0.213352,0.00481141,1.00126 beta-lactamase_625_K32Q,beta-lactamase_625_32,TEM-1,beta-lactamase_625,P62593,1.00126,NO,32,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.984,-2.601,0.617,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.213352,0.00401283,1.00126 kka2_1:1_C77C,kka2_1:1_77,Kka2,kka2_1:1,P00552,1.00126,NO,77,C,C,CC,Special,Special,5.07,5.07,0,0,121,121,0,108.5,108.5,0,-1.477,-1.477,,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.520039,0.00441216,1.00126 kka2_1:4_A222A,kka2_1:4_222,Kka2,kka2_1:4,P00552,1.00126,NO,222,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.725,-0.725,,,,H,A,0.46,-1.21,,,,HHH,-1.10833,0.168804,0.00207657,1.00126 beta-lactamase_156_D113I,beta-lactamase_156_113,TEM-1,beta-lactamase_156,P62593,1.00127,NO,113,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.829,-4.028,2.199,,0.665,T,A,0.75,0.91,2.973,,73.08,PAO,-1.703,0.111618,0.00474112,1.00127 beta-lactamase_156_S221F,beta-lactamase_156_221,TEM-1,beta-lactamase_156,P62593,1.00127,NO,221,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.754,-4.221,2.467,,0.624,H,A,0.27,-0.2,17.729,17.729,74.48,BPH,-1.59967,0.111618,0.0046094,1.00127 beta-lactamase_2500_Q276L,beta-lactamase_2500_276,TEM-1,beta-lactamase_2500,P62593,1.00127,NO,276,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.361275,0.0191712,1.00127 beta-lactamase_2500_R275Q,beta-lactamase_2500_275,TEM-1,beta-lactamase_2500,P62593,1.00127,NO,275,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.361275,0.0141984,1.00127 beta-lactamase_39_S104R,beta-lactamase_39_104,TEM-1,beta-lactamase_39,P62593,1.00127,NO,104,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.015,-3.804,2.789,,0.04,,b,0.27,0.57,4.02,,63.29,HPO,-1.05267,0.0495842,0.00218083,1.00127 kka2_1:4_N195N,kka2_1:4_195,Kka2,kka2_1:4,P00552,1.00127,NO,195,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-0.836,-0.836,,,0.037,G,A,0.61,-1.36,1.944,,48.11,OPH,-1.26567,0.168804,0.00276134,1.00127 beta-lactamase_156_I245T,beta-lactamase_156_245,TEM-1,beta-lactamase_156,P62593,1.00128,NO,245,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.111618,0.00391032,1.00128 beta-lactamase_2500_E272T,beta-lactamase_2500_272,TEM-1,beta-lactamase_2500,P62593,1.00128,NO,272,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.361275,0.00545371,1.00128 beta-lactamase_39_A40K,beta-lactamase_39_40,TEM-1,beta-lactamase_39,P62593,1.00128,NO,40,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.402,-3.658,2.256,,0.155,S,B,0.46,0.21,0.783,,73.78,OHB,-1.40267,0.0495842,0.00490026,1.00128 beta-lactamase_625_T193S,beta-lactamase_625_193,TEM-1,beta-lactamase_625,P62593,1.00128,NO,193,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.914,-2.571,0.657,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.213352,0.00482669,1.00128 beta-lactamase_A170S,beta-lactamase_170,TEM-1,beta-lactamase,P62593,1.00128,NO,170,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.237,-3.188,1.951,5.19261,0.126,,L,2.34,-0.35,2.427,,64.69,AHH,-1.63267,0.221079,0.00431903,1.00128 gb1_T270L,gb1_270,gb1,gb1,P06654,1.00128,NO,270,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-3.15,-3.15,0,,,,,,,1.326,,45.54,HPH,-1.843,0.177985,0.00223707,1.00128 kka2_1:4_D220D,kka2_1:4_220,Kka2,kka2_1:4,P00552,1.00128,NO,220,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.787,-0.787,,,,H,A,0.75,-1.14,1.237,,46.59,PAH,-1.152,0.168804,0.00158066,1.00128 kka2_1:8_D220D,kka2_1:8_220,Kka2,kka2_1:8,P00552,1.00128,NO,220,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.787,-0.787,,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.100394,0.00158066,1.00128 kka2_1:8_D220D,kka2_1:8_220,Kka2,kka2_1:8,P00552,1.00128,NO,220,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.787,-0.787,,,,H,A,0.29,-1.14,7.65,,46.59,PAH,-1.152,0.100394,0.00158066,1.00128 PSD95pdz3_L349W,PSD95pdz3_349,PSD95pdz3,PSD95pdz3,P31016,1.00128,NO,349,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.347,-4.779,3.432,5.14696,,,,,24.6438,,,,AHP,-1.37667,0.0758425,0.00071841,1.00128 beta-lactamase_156_A246T,beta-lactamase_156_246,TEM-1,beta-lactamase_156,P62593,1.00129,NO,246,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.121,-3.507,1.386,,0.01,E,B,0.46,-1.01,1.959,,73.78,HHH,-1.55633,0.111618,0.00569458,1.00129 beta-lactamase_2500_E238A,beta-lactamase_2500_238,TEM-1,beta-lactamase_2500,P62593,1.00129,NO,238,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.361275,0.00743256,1.00129 beta-lactamase_39_R92E,beta-lactamase_39_92,TEM-1,beta-lactamase_39,P62593,1.00129,NO,92,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.718,-2.624,0.906,,0.479,E,B,1.2,1.36,0.389,,65.38,BBH,-1.50367,0.0495842,0.00429626,1.00129 beta-lactamase_625_A235S,beta-lactamase_625_235,TEM-1,beta-lactamase_625,P62593,1.00129,NO,235,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.266,-2.058,0.792,,0.32,E,B,0.46,-0.86,0.281,,50,OHO,-0.89,0.213352,0.00493474,1.00129 Pab1_V148M,Pab1_148,Pab1,Pab1,P04147,1.00129,NO,148,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.875,-4.307,2.432,,,,,,,,,,PHH,-1.43033,0.175299,0.00179641,1.00129 beta-lactamase_39_S256K,beta-lactamase_39_256,TEM-1,beta-lactamase_39,P62593,1.0013,NO,256,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.0495842,0.00710634,1.0013 kka2_1:2_G10M,kka2_1:2_10,Kka2,kka2_1:2,P00552,1.0013,NO,10,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.921,-4.699,2.778,,,,,,,2.192,,71.59,HOP,-2.10733,0.295029,0.00289233,1.0013 beta-lactamase_156_R91N,beta-lactamase_156_91,TEM-1,beta-lactamase_156,P62593,1.00131,NO,91,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.392,-3.596,2.204,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.111618,0.00380226,1.00131 beta-lactamase_625_G236S,beta-lactamase_625_236,TEM-1,beta-lactamase_625,P62593,1.00131,NO,236,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.784,-2.475,1.691,,0.241,,b,0.29,-0.59,3.506,,64.69,HOO,-1.025,0.213352,0.00162372,1.00131 beta-lactamase_N173F,beta-lactamase_173,TEM-1,beta-lactamase,P62593,1.00131,NO,173,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-2.663,-4.355,1.692,7.02497,1.044,T,l,0.09,1.25,1.88,,77.62,OPA,-1.46633,0.221079,0.0033769,1.00131 kka2_1:8_H188H,kka2_1:8_188,Kka2,kka2_1:8,P00552,1.00131,NO,188,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-0.913,-0.913,,,0.006,,A,0.87,-1.02,1.241,,47.73,PBO,-0.927333,0.100394,0.00273139,1.00131 kka2_1:8_H188H,kka2_1:8_188,Kka2,kka2_1:8,P00552,1.00131,NO,188,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-0.913,-0.913,,,0.006,,A,0.87,-1.02,1.241,,47.73,PBO,-0.927333,0.100394,0.00273139,1.00131 kka2_1:8_V185V,kka2_1:8_185,Kka2,kka2_1:8,P00552,1.00131,NO,185,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.045,-1.045,,,0.058,E,B,1.48,-0.49,1.234,,46.97,HHH,-1.184,0.100394,0.00367031,1.00131 kka2_1:8_V185V,kka2_1:8_185,Kka2,kka2_1:8,P00552,1.00131,NO,185,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.045,-1.045,,,0.058,E,B,1.48,-0.49,1.234,,46.97,HHH,-1.184,0.100394,0.00367031,1.00131 beta-lactamase_39_T107M,beta-lactamase_39_107,TEM-1,beta-lactamase_39,P62593,1.00132,NO,107,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.117,-4.531,3.414,,,G,A,0.22,-0.06,2.686,,67.83,HPA,-1.265,0.0495842,0.00239347,1.00132 beta-lactamase_156_E166C,beta-lactamase_156_166,TEM-1,beta-lactamase_156,P62593,1.00133,NO,166,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.756,-5.069,3.313,,0.508,G,A,1.04,1.05,2.393,,73.08,OAH,-1.42233,0.111618,0.00512989,1.00133 beta-lactamase_156_N50T,beta-lactamase_156_50,TEM-1,beta-lactamase_156,P62593,1.00133,NO,50,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-2.979,-2.678,-0.301,,0.912,T,A,0.61,1.24,13.295,13.295,77.62,HPP,-2.134,0.111618,0.0047211,1.00133 beta-lactamase_A225C,beta-lactamase_225,TEM-1,beta-lactamase,P62593,1.00133,NO,225,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.845,-5.105,3.26,6.5181,1,T,B,0.58,-0.38,4.077,,74.48,OHO,-1.39967,0.221079,0.00465057,1.00133 beta-lactamase_156_I140Q,beta-lactamase_156_140,TEM-1,beta-lactamase_156,P62593,1.00134,NO,140,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.733,-4.321,2.588,,0.128,H,A,0.48,0.41,1.16,,73.08,PHO,-1.48733,0.111618,0.00597777,1.00134 beta-lactamase_156_S57T,beta-lactamase_156_57,TEM-1,beta-lactamase_156,P62593,1.00134,NO,57,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.918,-2.297,0.379,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.111618,0.00492804,1.00134 beta-lactamase_156_V101E,beta-lactamase_156_101,TEM-1,beta-lactamase_156,P62593,1.00134,NO,101,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.295,-2.851,1.556,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.111618,0.00374492,1.00134 beta-lactamase_2500_Q37E,beta-lactamase_2500_37,TEM-1,beta-lactamase_2500,P62593,1.00134,NO,37,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.134,-2.427,0.293,,0.613,H,A,0.64,1.98,1.318,,73.08,APH,-2.06967,0.361275,0.00425833,1.00134 beta-lactamase_S96G,beta-lactamase_96,TEM-1,beta-lactamase,P62593,1.00134,NO,96,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.27,-2.481,0.211,5.29889,0.368,,b,0.25,0.39,32.348,32.348,73.78,HPP,-2.019,0.221079,0.00551835,1.00134 kka2_1:8_G164Y,kka2_1:8_164,Kka2,kka2_1:8,P00552,1.00134,NO,164,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.869,-4.442,3.573,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.100394,0.00442091,1.00134 kka2_1:8_G164Y,kka2_1:8_164,Kka2,kka2_1:8,P00552,1.00134,NO,164,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.869,-4.442,3.573,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.100394,0.00442091,1.00134 PSD95pdz3_L349M,PSD95pdz3_349,PSD95pdz3,PSD95pdz3,P31016,1.00134,NO,349,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.347,-3.487,2.14,5.14696,,,,,24.6438,,,,AHP,-1.37667,0.0758425,0.00071841,1.00134 beta-lactamase_156_K286S,beta-lactamase_156_286,TEM-1,beta-lactamase_156,P62593,1.00135,NO,286,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.111618,,1.00135 beta-lactamase_156_P60C,beta-lactamase_156_60,TEM-1,beta-lactamase_156,P62593,1.00135,NO,60,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-2.469,-4.889,2.42,,0.256,T,A,0.52,-0.56,2.947,,77.62,BOA,-1.97633,0.111618,0.00521318,1.00135 beta-lactamase_625_A34G,beta-lactamase_625_34,TEM-1,beta-lactamase_625,P62593,1.00135,NO,34,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.059,-3.469,1.41,,,H,A,0.46,-0.54,3.614,,73.78,AHA,-1.74967,0.213352,0.00407913,1.00135 kka2_1:4_R217R,kka2_1:4_217,Kka2,kka2_1:4,P00552,1.00135,NO,217,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.158,-1.158,,,0.252,T,A,1.2,-0.59,2.074,,52.27,ABH,-1.127,0.168804,0.0047191,1.00135 beta-lactamase_A185A,beta-lactamase_185,TEM-1,beta-lactamase,P62593,1.00136,NO,185,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.406,-1.406,,4.89877,,H,A,2.34,-1.02,2.999,,65.03,HHP,-1.84033,0.221079,0.00467449,1.00136 kka2_1:8_D208D,kka2_1:8_208,Kka2,kka2_1:8,P00552,1.00136,NO,208,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.708,-0.708,,,0.36,,l,0.29,-1.01,,,,HAO,-0.929667,0.100394,0.00212588,1.00136 kka2_1:8_D208D,kka2_1:8_208,Kka2,kka2_1:8,P00552,1.00136,NO,208,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.708,-0.708,,,0.36,,l,0.29,-1.01,,,,HAO,-0.929667,0.100394,0.00212588,1.00136 kka2_1:8_G205G,kka2_1:8_205,Kka2,kka2_1:8,P00552,1.00136,NO,205,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.596,-0.596,,,,E,b,0.75,-1.05,,,,POH,-1.09933,0.100394,0.00221855,1.00136 kka2_1:8_G205G,kka2_1:8_205,Kka2,kka2_1:8,P00552,1.00136,NO,205,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.596,-0.596,,,,E,b,0.75,-1.05,,,,POH,-1.09933,0.100394,0.00221855,1.00136 beta-lactamase_0_Y95M,beta-lactamase_0_95,TEM-1,beta-lactamase_0,P62593,1.00137,NO,95,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-1.715,-4.404,2.689,,0.122,,b,0.21,-0.37,2.914,,77.62,BHP,-2.16167,0.0500837,0.00479449,1.00137 beta-lactamase_156_L38K,beta-lactamase_156_38,TEM-1,beta-lactamase_156,P62593,1.00137,NO,38,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.343,-3.749,2.406,,0.088,H,A,0.55,0.2,13.556,13.556,64.34,PHO,-1.78033,0.111618,0.00373244,1.00137 beta-lactamase_156_T187M,beta-lactamase_156_187,TEM-1,beta-lactamase_156,P62593,1.00137,NO,187,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.401,-4.516,3.115,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.111618,0.00491782,1.00137 beta-lactamase_625_A170W,beta-lactamase_625_170,TEM-1,beta-lactamase_625,P62593,1.00137,NO,170,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.237,-5.233,3.996,,0.126,,L,0.46,-0.35,3.626,,64.69,AHH,-1.63267,0.213352,0.00431903,1.00137 beta-lactamase_625_M270S,beta-lactamase_625_270,TEM-1,beta-lactamase_625,P62593,1.00137,NO,270,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.213352,0.00767762,1.00137 beta-lactamase_625_G226T,beta-lactamase_625_226,TEM-1,beta-lactamase_625,P62593,1.00138,NO,226,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.461,-3.599,2.138,,0.701,T,l,0.29,-0.25,3.199,,74.48,HOH,-1.42933,0.213352,0.00665294,1.00138 beta-lactamase_156_A246M,beta-lactamase_156_246,TEM-1,beta-lactamase_156,P62593,1.00139,NO,246,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.121,-2.882,0.761,,0.01,E,B,0.46,-1.01,1.959,,73.78,HHH,-1.55633,0.111618,0.00569458,1.00139 beta-lactamase_39_Q276T,beta-lactamase_39_276,TEM-1,beta-lactamase_39,P62593,1.00139,NO,276,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.0495842,0.0191712,1.00139 beta-lactamase_39_V78M,beta-lactamase_39_78,TEM-1,beta-lactamase_39,P62593,1.00139,NO,78,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.459,-2.823,1.364,,,H,A,0.44,-0.47,1.132,,63.64,HHH,-1.17833,0.0495842,0.00492501,1.00139 beta-lactamase_625_F228C,beta-lactamase_625_228,TEM-1,beta-lactamase_625,P62593,1.00139,NO,228,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-2.342,-5.075,2.733,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.213352,0.0046669,1.00139 beta-lactamase_625_M66V,beta-lactamase_625_66,TEM-1,beta-lactamase_625,P62593,1.00139,NO,66,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.362,-2.395,1.033,,0.013,,A,0.55,-0.7,1.659,,73.08,OHH,-1.49567,0.213352,0.00412876,1.00139 beta-lactamase_625_T27S,beta-lactamase_625_27,TEM-1,beta-lactamase_625,P62593,1.00139,NO,27,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.905,-2.606,0.701,,0.007,H,A,0.22,-0.37,3.72,,93.01,APH,-1.97933,0.213352,0.00306559,1.00139 beta-lactamase_156_G243A,beta-lactamase_156_243,TEM-1,beta-lactamase_156,P62593,1.0014,NO,243,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.532,,,,,E,B,0.77,-1.24,2.866,,50,BOH,-1.46867,0.111618,0.00464034,1.0014 beta-lactamase_2500_A211K,beta-lactamase_2500_211,TEM-1,beta-lactamase_2500,P62593,1.0014,NO,211,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.896,-3.538,1.642,,0.369,T,A,0.46,-0.69,2.061,,77.62,AHA,-1.94633,0.361275,0.00648183,1.0014 beta-lactamase_39_A84M,beta-lactamase_39_84,TEM-1,beta-lactamase_39,P62593,1.0014,NO,84,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.651,-4.707,3.056,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.0495842,0.00503822,1.0014 beta-lactamase_625_L28T,beta-lactamase_625_28,TEM-1,beta-lactamase_625,P62593,1.0014,NO,28,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.579,-3.444,1.865,,0.277,H,A,0.55,-0.16,2.716,,93.01,PHH,-2.11333,0.213352,0.00359321,1.0014 beta-lactamase_625_S241G,beta-lactamase_625_241,TEM-1,beta-lactamase_625,P62593,1.0014,NO,241,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.213352,0.00452736,1.0014 Pab1_E174E,Pab1_174,Pab1,Pab1,P04147,1.0014,NO,174,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.422,-1.422,,,0.578,S,A,,0.38,,,,HAA,-1.65133,0.175299,0.00077863,1.0014 beta-lactamase_2500_L223T,beta-lactamase_2500_223,TEM-1,beta-lactamase_2500,P62593,1.00141,NO,223,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.055,-2.595,1.54,,0.27,,B,0.55,0.09,1.334,,74.48,HHO,-1.35033,0.361275,0.00372793,1.00141 beta-lactamase_625_H24A,beta-lactamase_625_24,TEM-1,beta-lactamase_625,P62593,1.00141,NO,24,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-2.481,-2.265,-0.216,,,,,,,2.708,,93.01,OBO,-2.0035,0.213352,0.00238894,1.00141 beta-lactamase_625_Q37N,beta-lactamase_625_37,TEM-1,beta-lactamase_625,P62593,1.00141,NO,37,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.134,-3.706,1.572,,0.613,H,A,0.64,1.98,1.318,,73.08,APH,-2.06967,0.213352,0.00425833,1.00141 kka2_1:8_V186V,kka2_1:8_186,Kka2,kka2_1:8,P00552,1.00141,NO,186,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.011,-1.011,,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.100394,0.00409703,1.00141 kka2_1:8_V186V,kka2_1:8_186,Kka2,kka2_1:8,P00552,1.00141,NO,186,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.011,-1.011,,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.100394,0.00409703,1.00141 beta-lactamase_625_E169G,beta-lactamase_625_169,TEM-1,beta-lactamase_625,P62593,1.00142,NO,169,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.23,-3.348,2.118,,0.337,,A,1.04,1,1.806,,73.08,PAH,-1.16533,0.213352,0.00400994,1.00142 beta-lactamase_625_W163Q,beta-lactamase_625_163,TEM-1,beta-lactamase_625,P62593,1.00142,NO,163,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-1.843,-2.929,1.086,,0.467,,B,0.47,-0.5,5.019,,63.99,BHA,-1.269,0.213352,0.00418955,1.00142 beta-lactamase_156_A247G,beta-lactamase_156_247,TEM-1,beta-lactamase_156,P62593,1.00143,NO,247,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.111618,0.00611275,1.00143 beta-lactamase_2500_L199S,beta-lactamase_2500_199,TEM-1,beta-lactamase_2500,P62593,1.00143,NO,199,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-2.942,-2.568,-0.374,,0.832,H,A,0.55,0.42,15.504,15.504,77.62,PHH,-2.32933,0.361275,0.0048649,1.00143 beta-lactamase_39_T69H,beta-lactamase_39_69,TEM-1,beta-lactamase_39,P62593,1.00143,NO,69,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-0.973,-4.716,3.743,,,G,A,0.22,-1.24,4.194,,93.01,PPH,-1.01833,0.0495842,0.00127498,1.00143 beta-lactamase_625_M184F,beta-lactamase_625_184,TEM-1,beta-lactamase_625,P62593,1.00143,NO,184,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.593,-2.94,1.347,,,H,A,0.55,-0.87,2.765,,62.94,HHH,-1.41,0.213352,0.00356019,1.00143 beta-lactamase_625_W163R,beta-lactamase_625_163,TEM-1,beta-lactamase_625,P62593,1.00143,NO,163,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-1.843,-2.51,0.667,,0.467,,B,0.47,-0.5,5.019,,63.99,BHA,-1.269,0.213352,0.00418955,1.00143 kka2_1:8_C77C,kka2_1:8_77,Kka2,kka2_1:8,P00552,1.00143,NO,77,C,C,CC,Special,Special,5.07,5.07,0,0,121,121,0,108.5,108.5,0,-1.477,-1.477,,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.100394,0.00441216,1.00143 kka2_1:8_C77C,kka2_1:8_77,Kka2,kka2_1:8,P00552,1.00143,NO,77,C,C,CC,Special,Special,5.07,5.07,0,0,121,121,0,108.5,108.5,0,-1.477,-1.477,,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.100394,0.00441216,1.00143 kka2_1:8_L232I,kka2_1:8_232,Kka2,kka2_1:8,P00552,1.00143,NO,232,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.514,-2.661,1.147,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.100394,0.00800103,1.00143 kka2_1:8_L232I,kka2_1:8_232,Kka2,kka2_1:8,P00552,1.00143,NO,232,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.514,-2.661,1.147,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.100394,0.00800103,1.00143 beta-lactamase_156_P250T,beta-lactamase_156_250,TEM-1,beta-lactamase_156,P62593,1.00144,NO,250,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.111618,0.00550899,1.00144 beta-lactamase_2500_Q204L,beta-lactamase_2500_204,TEM-1,beta-lactamase_2500,P62593,1.00144,NO,204,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-1.382,-2.716,1.334,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.361275,0.00364106,1.00144 beta-lactamase_625_S80M,beta-lactamase_625_80,TEM-1,beta-lactamase_625,P62593,1.00144,NO,80,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.029,-4.671,2.642,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.213352,0.00565569,1.00144 kka2_1:8_G233G,kka2_1:8_233,Kka2,kka2_1:8,P00552,1.00144,NO,233,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.748,-0.748,,,0.172,,b,0.75,-0.27,1.134,,49.24,HOO,-1.72067,0.100394,0.00232366,1.00144 kka2_1:8_G233G,kka2_1:8_233,Kka2,kka2_1:8,P00552,1.00144,NO,233,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.748,-0.748,,,0.172,,b,0.75,-0.27,1.134,,49.24,HOO,-1.72067,0.100394,0.00232366,1.00144 kka2_1:8_R226R,kka2_1:8_226,Kka2,kka2_1:8,P00552,1.00144,NO,226,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.392,-1.392,,,0.222,H,A,0.16,-0.71,3.818,,56.06,PBA,-1.84767,0.100394,0.0108032,1.00144 kka2_1:8_R226R,kka2_1:8_226,Kka2,kka2_1:8,P00552,1.00144,NO,226,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.392,-1.392,,,0.222,H,A,0.16,-0.71,3.818,,56.06,PBA,-1.84767,0.100394,0.0108032,1.00144 kka2_1:8_V84L,kka2_1:8_84,Kka2,kka2_1:8,P00552,1.00144,NO,84,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-2.279,-2.527,0.248,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.100394,0.00724019,1.00144 kka2_1:8_V84L,kka2_1:8_84,Kka2,kka2_1:8,P00552,1.00144,NO,84,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-2.279,-2.527,0.248,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.100394,0.00724019,1.00144 beta-lactamase_39_L79E,beta-lactamase_39_79,TEM-1,beta-lactamase_39,P62593,1.00145,NO,79,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.842,-3.887,3.045,,0.007,H,A,0.55,-0.16,0.823,,50.35,HHP,-1.44333,0.0495842,0.000947397,1.00145 beta-lactamase_625_L284F,beta-lactamase_625_284,TEM-1,beta-lactamase_625,P62593,1.00145,NO,284,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.213352,0.0686156,1.00145 beta-lactamase_156_K286W,beta-lactamase_156_286,TEM-1,beta-lactamase_156,P62593,1.00146,NO,286,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.111,-3.724,2.613,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.111618,,1.00146 beta-lactamase_2500_S122R,beta-lactamase_2500_122,TEM-1,beta-lactamase_2500,P62593,1.00146,NO,122,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.406,-3.131,0.725,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.361275,0.00497825,1.00146 kka2_1:8_A78A,kka2_1:8_78,Kka2,kka2_1:8,P00552,1.00146,NO,78,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.744,-1.744,,,0.078,,B,1.04,-0.53,1.251,,56.06,OHH,-1.863,0.100394,0.00457299,1.00146 kka2_1:8_A78A,kka2_1:8_78,Kka2,kka2_1:8,P00552,1.00146,NO,78,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.744,-1.744,,,0.078,,B,1.04,-0.53,1.251,,56.06,OHH,-1.863,0.100394,0.00457299,1.00146 beta-lactamase_2500_L199T,beta-lactamase_2500_199,TEM-1,beta-lactamase_2500,P62593,1.00147,NO,199,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-2.942,-2.763,-0.179,,0.832,H,A,0.55,0.42,15.504,15.504,77.62,PHH,-2.32933,0.361275,0.0048649,1.00147 beta-lactamase_625_N173A,beta-lactamase_625_173,TEM-1,beta-lactamase_625,P62593,1.00147,NO,173,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-2.663,-2.432,-0.231,,1.044,T,l,0.61,1.25,1.426,,77.62,OPA,-1.46633,0.213352,0.0033769,1.00147 kka2_1:4_D208D,kka2_1:4_208,Kka2,kka2_1:4,P00552,1.00147,NO,208,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.708,-0.708,,,0.36,.,l,0.75,-1.01,,,,HAO,-0.929667,0.168804,0.00212588,1.00147 kka2_1:4_V185V,kka2_1:4_185,Kka2,kka2_1:4,P00552,1.00147,NO,185,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.045,-1.045,,,0.058,E,B,0.44,-0.49,0.255,,46.97,HHH,-1.184,0.168804,0.00367031,1.00147 Pab1_Q194D,Pab1_194,Pab1,Pab1,P04147,1.00147,NO,194,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.179,-3.548,1.369,,,,,,,,,,OPA,-1.59767,0.175299,0.0016145,1.00147 beta-lactamase_156_L135Y,beta-lactamase_156_135,TEM-1,beta-lactamase_156,P62593,1.00148,NO,135,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.002,-3.991,2.989,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.111618,0.00244423,1.00148 beta-lactamase_39_M67Y,beta-lactamase_39_67,TEM-1,beta-lactamase_39,P62593,1.00148,NO,67,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-2.231,-4.282,2.051,,0.006,G,P,0.55,-0.81,1.463,,65.03,HHP,-1.502,0.0495842,0.00409753,1.00148 hsp90_Q582H,hsp90_582,hsp90,hsp90,P02829,1.00148,NO,582,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-3.278,-3.833,0,4.91603,0.453,S,B,,0.67,,,,OPH,-3.249,0.368192,0.000222939,1.00148 kka2_1:4_A78A,kka2_1:4_78,Kka2,kka2_1:4,P00552,1.00148,NO,78,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.744,-1.744,,,0.078,.,B,0.46,-0.53,0.594,,56.06,OHH,-1.863,0.168804,0.00457299,1.00148 kka2_1:4_C77C,kka2_1:4_77,Kka2,kka2_1:4,P00552,1.00148,NO,77,C,C,CC,Special,Special,5.07,5.07,0,0,121,121,0,108.5,108.5,0,-1.477,-1.477,,,0.229,B,b,0.46,-0.57,2.499,,63.26,OOH,-1.55667,0.168804,0.00441216,1.00148 kka2_1:4_R226R,kka2_1:4_226,Kka2,kka2_1:4,P00552,1.00148,NO,226,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.392,-1.392,,,0.222,H,A,1.2,-0.71,3.654,,56.06,PBA,-1.84767,0.168804,0.0108032,1.00148 PSD95pdz3_L323Y,PSD95pdz3_323,PSD95pdz3,PSD95pdz3,P31016,1.00148,NO,323,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.347,-3.619,2.272,5.12397,,,,,13.8825,,,,OHO,-1.121,0.0758425,0.00104644,1.00148 beta-lactamase_39_D174F,beta-lactamase_39_174,TEM-1,beta-lactamase_39,P62593,1.00149,NO,174,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.738,-4.292,3.554,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.0495842,0.00125633,1.00149 beta-lactamase_39_E210N,beta-lactamase_39_210,TEM-1,beta-lactamase_39,P62593,1.00149,NO,210,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.319,-3.904,1.585,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.0495842,0.00663582,1.00149 beta-lactamase_39_Q276V,beta-lactamase_39_276,TEM-1,beta-lactamase_39,P62593,1.00149,NO,276,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.0495842,0.0191712,1.00149 beta-lactamase_625_A225Y,beta-lactamase_625_225,TEM-1,beta-lactamase_625,P62593,1.00149,NO,225,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.845,-4.327,2.482,,1,T,B,0.46,-0.38,9.874,9.874,74.48,OHO,-1.39967,0.213352,0.00465057,1.00149 kka2_1:4_G205G,kka2_1:4_205,Kka2,kka2_1:4,P00552,1.00149,NO,205,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.596,-0.596,,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.168804,0.00221855,1.00149 Pab1_K180W,Pab1_180,Pab1,Pab1,P04147,1.00149,NO,180,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.945,-5.4,3.455,,,,,,,,,,HBA,-1.575,0.175299,0.00295933,1.00149 beta-lactamase_156_K32M,beta-lactamase_156_32,TEM-1,beta-lactamase_156,P62593,1.0015,NO,32,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.984,-4.613,2.629,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.111618,0.00401283,1.0015 beta-lactamase_156_N152C,beta-lactamase_156_152,TEM-1,beta-lactamase_156,P62593,1.0015,NO,152,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-2.757,-5.071,2.314,,0.863,H,A,0.61,0.92,4.038,,77.62,BPH,-2.97,0.111618,0.00471429,1.0015 beta-lactamase_2500_A84L,beta-lactamase_2500_84,TEM-1,beta-lactamase_2500,P62593,1.0015,NO,84,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.651,-3.508,1.857,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.361275,0.00503822,1.0015 beta-lactamase_625_T158S,beta-lactamase_625_158,TEM-1,beta-lactamase_625,P62593,1.0015,NO,158,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.116,-1.795,0.679,,0.036,,B,0.22,-0.85,3.771,,69.58,HPB,-1.269,0.213352,0.00341825,1.0015 beta-lactamase_D269S,beta-lactamase_269,TEM-1,beta-lactamase,P62593,1.0015,NO,269,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.156,-2.792,0.636,5.47645,0.646,H,A,0.23,0.4,21.796,21.796,77.62,HAA,-1.96733,0.221079,0.00950944,1.0015 beta-lactamase_K53S,beta-lactamase_53,TEM-1,beta-lactamase,P62593,1.0015,NO,53,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-2.313,-2.879,0.566,5.93654,0.589,,B,1.82,1.15,19.72,19.72,77.62,OBH,-2.1,0.221079,0.00383383,1.0015 beta-lactamase_R59R,beta-lactamase_59,TEM-1,beta-lactamase,P62593,1.0015,NO,59,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.345,-1.345,,5.49837,0.329,S,L,0.68,-0.09,1.806,,73.08,HBO,-2.24267,0.221079,0.00318082,1.0015 kka2_1:4_H188H,kka2_1:4_188,Kka2,kka2_1:4,P00552,1.0015,NO,188,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-0.913,-0.913,,,0.006,.,A,0.17,-1.02,1.241,,47.73,PBO,-0.927333,0.168804,0.00273139,1.0015 PSD95pdz3_Q384M,PSD95pdz3_384,PSD95pdz3,PSD95pdz3,P31016,1.0015,NO,384,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-1.699,-3.937,2.238,5.49339,,,,,23.54,,,,OPP,-1.41333,0.0758425,0.000216736,1.0015 beta-lactamase_0_E238W,beta-lactamase_0_238,TEM-1,beta-lactamase_0,P62593,1.00151,NO,238,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.0500837,0.00743256,1.00151 kka2_1:8_D190D,kka2_1:8_190,Kka2,kka2_1:8,P00552,1.00151,NO,190,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.708,-0.708,,,0.213,S,b,0.29,-0.82,,,,OAH,-0.711667,0.100394,0.00247989,1.00151 kka2_1:8_D190D,kka2_1:8_190,Kka2,kka2_1:8,P00552,1.00151,NO,190,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.708,-0.708,,,0.213,S,b,0.29,-0.82,,,,OAH,-0.711667,0.100394,0.00247989,1.00151 beta-lactamase_156_L28G,beta-lactamase_156_28,TEM-1,beta-lactamase_156,P62593,1.00152,NO,28,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.579,-3.602,2.023,,0.277,H,A,0.55,-0.16,3.262,,93.01,PHH,-2.11333,0.111618,0.00359321,1.00152 beta-lactamase_156_T198F,beta-lactamase_156_198,TEM-1,beta-lactamase_156,P62593,1.00152,NO,198,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.168,-4.258,2.09,,0.489,,B,0.22,-0.13,10.771,10.771,73.78,HPH,-1.98767,0.111618,0.004311,1.00152 kka2_1:4_G233G,kka2_1:4_233,Kka2,kka2_1:4,P00552,1.00152,NO,233,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.748,-0.748,,,0.172,.,b,0.29,-0.27,1.513,,49.24,HOO,-1.72067,0.168804,0.00232366,1.00152 beta-lactamase_156_A148F,beta-lactamase_156_148,TEM-1,beta-lactamase_156,P62593,1.00153,NO,148,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.757,-4.389,2.632,,0.379,H,A,0.46,-0.55,3.551,,72.73,PHH,-1.40167,0.111618,0.00547053,1.00153 Pab1_L190F,Pab1_190,Pab1,Pab1,P04147,1.00153,NO,190,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.325,-3.616,2.291,,0.489,E,B,,2.59,,,,HHH,-1.31033,0.175299,0.00132347,1.00153 beta-lactamase_156_K190H,beta-lactamase_156_190,TEM-1,beta-lactamase_156,P62593,1.00154,NO,190,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.994,-3.068,1.074,,0.371,H,A,2.34,0.16,1.513,,77.62,BBH,-1.64167,0.111618,0.00574527,1.00154 beta-lactamase_39_A182E,beta-lactamase_39_182,TEM-1,beta-lactamase_39,P62593,1.00154,NO,182,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.777,-2.345,0.568,,0.136,H,A,0.46,-0.66,2.598,,93.01,OHH,-1.27367,0.0495842,0.00559099,1.00154 beta-lactamase_625_Q37I,beta-lactamase_625_37,TEM-1,beta-lactamase_625,P62593,1.00154,NO,37,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.134,-4.024,1.89,,0.613,H,A,0.64,1.98,1.318,,73.08,APH,-2.06967,0.213352,0.00425833,1.00154 beta-lactamase_625_T193Y,beta-lactamase_625_193,TEM-1,beta-lactamase_625,P62593,1.00154,NO,193,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.914,-3.989,2.075,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.213352,0.00482669,1.00154 beta-lactamase_625_T263C,beta-lactamase_625_263,TEM-1,beta-lactamase_625,P62593,1.00154,NO,263,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.213352,0.0110582,1.00154 kka2_1:1_A78A,kka2_1:1_78,Kka2,kka2_1:1,P00552,1.00154,NO,78,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.744,-1.744,,,0.078,.,B,0.46,-0.53,0.206,,56.06,OHH,-1.863,0.520039,0.00457299,1.00154 kka2_1:4_D23Y,kka2_1:4_23,Kka2,kka2_1:4,P00552,1.00156,NO,23,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.459,-4.392,1.933,,0.695,E,B,0.75,-0.65,2.416,,65.53,HAH,-1.94033,0.168804,0.007195,1.00156 beta-lactamase_156_T147G,beta-lactamase_156_147,TEM-1,beta-lactamase_156,P62593,1.00157,NO,147,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.149,-2.499,1.35,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.111618,0.00226017,1.00157 beta-lactamase_2500_M127L,beta-lactamase_2500_127,TEM-1,beta-lactamase_2500,P62593,1.00157,NO,127,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-2.251,-2.123,-0.128,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.361275,0.00437927,1.00157 beta-lactamase_39_L199W,beta-lactamase_39_199,TEM-1,beta-lactamase_39,P62593,1.00157,NO,199,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-2.942,-5.582,2.64,,0.832,H,A,0.55,0.42,15.504,15.504,77.62,PHH,-2.32933,0.0495842,0.0048649,1.00157 beta-lactamase_625_K109P,beta-lactamase_625_109,TEM-1,beta-lactamase_625,P62593,1.00157,NO,109,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.734,-2.825,1.091,,0.787,G,A,2.34,2.21,7.243,,72.73,ABB,-1.63333,0.213352,0.00462493,1.00157 kka2_1:4_D190D,kka2_1:4_190,Kka2,kka2_1:4,P00552,1.00157,NO,190,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.708,-0.708,,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.168804,0.00247989,1.00157 kka2_1:8_G189G,kka2_1:8_189,Kka2,kka2_1:8,P00552,1.00157,NO,189,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.596,-0.596,,,0.034,S,l,0.75,-0.99,,,,BOA,-0.739,0.100394,0.00253688,1.00157 kka2_1:8_G189G,kka2_1:8_189,Kka2,kka2_1:8,P00552,1.00157,NO,189,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.596,-0.596,,,0.034,S,l,0.75,-0.99,,,,BOA,-0.739,0.100394,0.00253688,1.00157 kka2_1:8_G213G,kka2_1:8_213,Kka2,kka2_1:8,P00552,1.00157,NO,213,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.596,-0.596,,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.100394,0.00187654,1.00157 kka2_1:8_G213G,kka2_1:8_213,Kka2,kka2_1:8,P00552,1.00157,NO,213,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.596,-0.596,,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.100394,0.00187654,1.00157 beta-lactamase_156_A247K,beta-lactamase_156_247,TEM-1,beta-lactamase_156,P62593,1.00158,NO,247,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.111618,0.00611275,1.00158 beta-lactamase_39_S51R,beta-lactamase_39_51,TEM-1,beta-lactamase_39,P62593,1.00158,NO,51,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.526,-2.956,1.43,,0.496,T,A,0.27,0.26,2.964,,72.73,PPO,-1.88467,0.0495842,0.00504821,1.00158 kka2_1:2_A78A,kka2_1:2_78,Kka2,kka2_1:2,P00552,1.00158,NO,78,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.744,-1.744,,,0.078,.,B,0.46,-0.53,0.206,,56.06,OHH,-1.863,0.295029,0.00457299,1.00158 beta-lactamase_2500_S283I,beta-lactamase_2500_283,TEM-1,beta-lactamase_2500,P62593,1.00159,NO,283,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.638,-3.539,1.901,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.361275,0.0429138,1.00159 beta-lactamase_39_R242G,beta-lactamase_39_242,TEM-1,beta-lactamase_39,P62593,1.00159,NO,242,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.319,-3.802,2.483,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.0495842,0.00452879,1.00159 beta-lactamase_39_G265E,beta-lactamase_39_265,TEM-1,beta-lactamase_39,P62593,1.0016,NO,265,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.0495842,0.00811926,1.0016 beta-lactamase_39_G76S,beta-lactamase_39_76,TEM-1,beta-lactamase_39,P62593,1.0016,NO,76,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.189,-2.528,1.339,,,H,A,0.29,-0.67,2.145,,67.83,OOH,-1.22267,0.0495842,0.00476637,1.0016 gb1_V265M,gb1_265,gb1,gb1,P06654,1.0016,NO,265,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.843,-4.271,2.428,,,,,,,0.402,,11.83,OHA,-1.64567,0.177985,0.00360613,1.0016 beta-lactamase_156_R91I,beta-lactamase_156_91,TEM-1,beta-lactamase_156,P62593,1.00161,NO,91,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.392,-4.049,2.657,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.111618,0.00380226,1.00161 beta-lactamase_2500_E238Y,beta-lactamase_2500_238,TEM-1,beta-lactamase_2500,P62593,1.00161,NO,238,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.361275,0.00743256,1.00161 beta-lactamase_39_I140Q,beta-lactamase_39_140,TEM-1,beta-lactamase_39,P62593,1.00161,NO,140,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.733,-4.321,2.588,,0.128,H,A,0.48,0.41,1.16,,73.08,PHO,-1.48733,0.0495842,0.00597777,1.00161 beta-lactamase_39_R176E,beta-lactamase_39_176,TEM-1,beta-lactamase_39,P62593,1.00161,NO,176,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-0.863,-3.215,2.352,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.0495842,0.00105554,1.00161 beta-lactamase_39_S256G,beta-lactamase_39_256,TEM-1,beta-lactamase_39,P62593,1.00161,NO,256,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.0495842,0.00710634,1.00161 beta-lactamase_625_A278S,beta-lactamase_625_278,TEM-1,beta-lactamase_625,P62593,1.00161,NO,278,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.213352,0.0310297,1.00161 kka2_1:4_M148L,kka2_1:4_148,Kka2,kka2_1:4,P00552,1.00161,NO,148,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.847,-2.054,0.207,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.168804,0.00982664,1.00161 kka2_1:4_V186V,kka2_1:4_186,Kka2,kka2_1:4,P00552,1.00161,NO,186,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.011,-1.011,,,,E,B,0.44,-0.61,0.679,,45.83,HHP,-1.10967,0.168804,0.00409703,1.00161 beta-lactamase_156_T198S,beta-lactamase_156_198,TEM-1,beta-lactamase_156,P62593,1.00162,NO,198,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.168,-1.471,-0.697,,0.489,,B,0.22,-0.13,10.771,10.771,73.78,HPH,-1.98767,0.111618,0.004311,1.00162 beta-lactamase_156_T198Y,beta-lactamase_156_198,TEM-1,beta-lactamase_156,P62593,1.00162,NO,198,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.168,-4.211,2.043,,0.489,,B,0.22,-0.13,10.771,10.771,73.78,HPH,-1.98767,0.111618,0.004311,1.00162 beta-lactamase_2500_L196T,beta-lactamase_2500_196,TEM-1,beta-lactamase_2500,P62593,1.00162,NO,196,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-2.478,-2.588,0.11,,0.518,S,A,0.55,1.35,7.897,,77.62,AHH,-1.839,0.361275,0.00512144,1.00162 beta-lactamase_156_I245S,beta-lactamase_156_245,TEM-1,beta-lactamase_156,P62593,1.00163,NO,245,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.111618,0.00391032,1.00163 beta-lactamase_E237L,beta-lactamase_237,TEM-1,beta-lactamase,P62593,1.00163,NO,237,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.058,-2.988,0.93,5.42877,0.583,S,B,1.62,1.2,2.144,,77.62,OAB,-1.61467,0.221079,0.0048626,1.00163 beta-lactamase_39_P172A,beta-lactamase_39_172,TEM-1,beta-lactamase_39,P62593,1.00164,NO,172,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.998,-2.44,1.442,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.0495842,0.00312594,1.00164 beta-lactamase_39_R202H,beta-lactamase_39_202,TEM-1,beta-lactamase_39,P62593,1.00164,NO,202,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.292,-4.365,3.073,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.0495842,0.00321899,1.00164 beta-lactamase_625_K32G,beta-lactamase_625_32,TEM-1,beta-lactamase_625,P62593,1.00164,NO,32,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.984,-3.506,1.522,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.213352,0.00401283,1.00164 kka2_1:4_G213G,kka2_1:4_213,Kka2,kka2_1:4,P00552,1.00164,NO,213,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.596,-0.596,,,,E,b,0.75,-0.4,,,,HOH,-0.920333,0.168804,0.00187654,1.00164 beta-lactamase_0_M184Q,beta-lactamase_0_184,TEM-1,beta-lactamase_0,P62593,1.00165,NO,184,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.593,-3.011,1.418,,,H,A,0.55,-0.87,13.292,13.292,62.94,HHH,-1.41,0.0500837,0.00356019,1.00165 beta-lactamase_156_T264C,beta-lactamase_156_264,TEM-1,beta-lactamase_156,P62593,1.00165,NO,264,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.111618,0.0119399,1.00165 beta-lactamase_156_V82H,beta-lactamase_156_82,TEM-1,beta-lactamase_156,P62593,1.00165,NO,82,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.325,-4.872,3.547,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.111618,0.00397046,1.00165 beta-lactamase_39_A84V,beta-lactamase_39_84,TEM-1,beta-lactamase_39,P62593,1.00165,NO,84,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.651,-2.943,1.292,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.0495842,0.00503822,1.00165 beta-lactamase_39_G265H,beta-lactamase_39_265,TEM-1,beta-lactamase_39,P62593,1.00165,NO,265,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.0495842,0.00811926,1.00165 beta-lactamase_39_S283D,beta-lactamase_39_283,TEM-1,beta-lactamase_39,P62593,1.00165,NO,283,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.0495842,0.0429138,1.00165 beta-lactamase_0_I206P,beta-lactamase_0_206,TEM-1,beta-lactamase_0,P62593,1.00166,NO,206,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-2.429,-4.04,1.611,,0.173,H,A,0.48,-0.34,3.411,,77.62,HHA,-1.805,0.0500837,0.00528934,1.00166 beta-lactamase_156_K286R,beta-lactamase_156_286,TEM-1,beta-lactamase_156,P62593,1.00166,NO,286,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.111618,,1.00166 beta-lactamase_156_R41P,beta-lactamase_156_41,TEM-1,beta-lactamase_156,P62593,1.00166,NO,41,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-0.942,-3.877,2.935,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.111618,0.00123327,1.00166 beta-lactamase_2500_E166D,beta-lactamase_2500_166,TEM-1,beta-lactamase_2500,P62593,1.00166,NO,166,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.756,-2.259,0.503,,0.508,G,A,1.04,1.05,2.124,,73.08,OAH,-1.42233,0.361275,0.00512989,1.00166 beta-lactamase_625_A222L,beta-lactamase_625_222,TEM-1,beta-lactamase_625,P62593,1.00166,NO,222,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.103,-3.403,1.3,,0.233,H,A,0.46,-0.25,1.448,,77.62,PHH,-1.63733,0.213352,0.00466094,1.00166 beta-lactamase_625_G52A,beta-lactamase_625_52,TEM-1,beta-lactamase_625,P62593,1.00166,NO,52,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.149,-2.316,1.167,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.213352,0.00340138,1.00166 beta-lactamase_156_H24R,beta-lactamase_156_24,TEM-1,beta-lactamase_156,P62593,1.00167,NO,24,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-2.481,-3.749,1.268,,,,,,,2.708,,93.01,OBO,-2.0035,0.111618,0.00238894,1.00167 beta-lactamase_156_N152H,beta-lactamase_156_152,TEM-1,beta-lactamase_156,P62593,1.00167,NO,152,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-2.757,-3.372,0.615,,0.863,H,A,0.61,0.92,4.038,,77.62,BPH,-2.97,0.111618,0.00471429,1.00167 beta-lactamase_156_S122L,beta-lactamase_156_122,TEM-1,beta-lactamase_156,P62593,1.00167,NO,122,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.406,-2.918,0.512,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.111618,0.00497825,1.00167 beta-lactamase_625_E195C,beta-lactamase_625_195,TEM-1,beta-lactamase_625,P62593,1.00167,NO,195,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.186,-5.238,3.052,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.213352,0.00496565,1.00167 kka2_1:1_T73T,kka2_1:1_73,Kka2,kka2_1:1,P00552,1.00167,NO,73,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.51,-2.51,,,0.309,H,A,0.22,0.35,4.126,,56.06,PPO,-2.02333,0.520039,0.00628605,1.00167 beta-lactamase_156_G154W,beta-lactamase_156_154,TEM-1,beta-lactamase_156,P62593,1.00168,NO,154,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.823,-5.233,4.41,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.111618,0.00180205,1.00168 beta-lactamase_156_G39A,beta-lactamase_156_39,TEM-1,beta-lactamase_156,P62593,1.00168,NO,39,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.864,-2.728,0.864,,0.701,T,L,0.29,0.47,1.454,,77.62,HOH,-1.53633,0.111618,0.00487611,1.00168 beta-lactamase_625_P217H,beta-lactamase_625_217,TEM-1,beta-lactamase_625,P62593,1.00168,NO,217,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-2.062,-3.354,1.292,,0.496,I,A,0.52,-0.33,1.087,,74.48,OOH,-1.64333,0.213352,0.00463211,1.00168 beta-lactamase_156_N152L,beta-lactamase_156_152,TEM-1,beta-lactamase_156,P62593,1.00169,NO,152,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-2.757,-3.55,0.793,,0.863,H,A,0.61,0.92,4.038,,77.62,BPH,-2.97,0.111618,0.00471429,1.00169 beta-lactamase_39_A247D,beta-lactamase_39_247,TEM-1,beta-lactamase_39,P62593,1.00169,NO,247,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.0495842,0.00611275,1.00169 beta-lactamase_A182G,beta-lactamase_182,TEM-1,beta-lactamase,P62593,1.00169,NO,182,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.777,-3.408,1.631,4.98609,0.136,H,A,0.52,-0.66,2.032,,93.01,OHH,-1.27367,0.221079,0.00559099,1.00169 beta-lactamase_156_G236A,beta-lactamase_156_236,TEM-1,beta-lactamase_156,P62593,1.0017,NO,236,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.784,-2.29,1.506,,0.241,,b,0.29,-0.59,1.883,,64.69,HOO,-1.025,0.111618,0.00162372,1.0017 beta-lactamase_156_G39T,beta-lactamase_156_39,TEM-1,beta-lactamase_156,P62593,1.0017,NO,39,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.864,-2.931,1.067,,0.701,T,L,0.29,0.47,1.454,,77.62,HOH,-1.53633,0.111618,0.00487611,1.0017 beta-lactamase_156_T112A,beta-lactamase_156_112,TEM-1,beta-lactamase_156,P62593,1.0017,NO,112,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.186,-1.933,-0.253,,0.921,T,A,0.22,1.06,2.87,,73.78,HPA,-1.925,0.111618,0.00531334,1.0017 beta-lactamase_39_L73G,beta-lactamase_39_73,TEM-1,beta-lactamase_39,P62593,1.00171,NO,73,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.507,-3.739,2.232,,,H,A,0.55,-0.64,2.09,,67.83,HHH,-1.487,0.0495842,0.00488983,1.00171 beta-lactamase_625_P25N,beta-lactamase_625_25,TEM-1,beta-lactamase_625,P62593,1.00171,NO,25,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.526,-3.702,2.176,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.213352,0.00347571,1.00171 beta-lactamase_39_G243T,beta-lactamase_39_243,TEM-1,beta-lactamase_39,P62593,1.00172,NO,243,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.0495842,0.00464034,1.00172 beta-lactamase_39_N134R,beta-lactamase_39_134,TEM-1,beta-lactamase_39,P62593,1.00172,NO,134,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-0.879,-3.446,2.567,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.0495842,0.000644786,1.00172 kka2_1:4_G189G,kka2_1:4_189,Kka2,kka2_1:4,P00552,1.00172,NO,189,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.596,-0.596,,,0.034,S,l,0.29,-0.99,,,,BOA,-0.739,0.168804,0.00253688,1.00172 kka2_1:8_L92V,kka2_1:8_92,Kka2,kka2_1:8,P00552,1.00172,NO,92,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.893,-2.208,1.315,,0.007,E,B,1.59,-0.19,1.719,,63.26,HHH,-0.962,0.100394,0.00307177,1.00172 kka2_1:8_L92V,kka2_1:8_92,Kka2,kka2_1:8,P00552,1.00172,NO,92,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.893,-2.208,1.315,,0.007,E,B,1.59,-0.19,1.719,,63.26,HHH,-0.962,0.100394,0.00307177,1.00172 beta-lactamase_156_F228T,beta-lactamase_156_228,TEM-1,beta-lactamase_156,P62593,1.00173,NO,228,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-2.342,-2.522,0.18,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.111618,0.0046669,1.00173 beta-lactamase_39_G253A,beta-lactamase_39_253,TEM-1,beta-lactamase_39,P62593,1.00173,NO,253,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.0495842,0.00786358,1.00173 beta-lactamase_156_T69S,beta-lactamase_156_69,TEM-1,beta-lactamase_156,P62593,1.00174,NO,69,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-0.973,-2.405,1.432,,,G,A,0.22,-1.24,4.194,,93.01,PPH,-1.01833,0.111618,0.00127498,1.00174 beta-lactamase_2500_S57E,beta-lactamase_2500_57,TEM-1,beta-lactamase_2500,P62593,1.00174,NO,57,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.918,-2.903,0.985,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.361275,0.00492804,1.00174 beta-lactamase_39_S266A,beta-lactamase_39_266,TEM-1,beta-lactamase_39,P62593,1.00174,NO,266,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.369,-2.686,1.317,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.0495842,0.0140785,1.00174 beta-lactamase_156_D83V,beta-lactamase_156_83,TEM-1,beta-lactamase_156,P62593,1.00175,NO,83,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.066,-3.762,2.696,,0.354,H,A,0.75,0.22,1.281,,48.95,HAH,-1.34733,0.111618,0.00205968,1.00175 beta-lactamase_156_T193I,beta-lactamase_156_193,TEM-1,beta-lactamase_156,P62593,1.00175,NO,193,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.914,-2.798,0.884,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.111618,0.00482669,1.00175 kka2_1:2_M120I,kka2_1:2_120,Kka2,kka2_1:2,P00552,1.00175,NO,120,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-3.877,-2.912,-0.965,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.295029,0.00265808,1.00175 kka2_1:8_K50R,kka2_1:8_50,Kka2,kka2_1:8,P00552,1.00175,NO,50,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-0.833,-2.445,1.612,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.100394,0.00138626,1.00175 kka2_1:8_K50R,kka2_1:8_50,Kka2,kka2_1:8,P00552,1.00175,NO,50,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-0.833,-2.445,1.612,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.100394,0.00138626,1.00175 beta-lactamase_156_L55T,beta-lactamase_156_55,TEM-1,beta-lactamase_156,P62593,1.00177,NO,55,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.86,-3.617,1.757,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.111618,0.00403741,1.00177 beta-lactamase_39_L135K,beta-lactamase_39_135,TEM-1,beta-lactamase_39,P62593,1.00177,NO,135,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.002,-3.751,2.749,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.0495842,0.00244423,1.00177 beta-lactamase_39_L160A,beta-lactamase_39_160,TEM-1,beta-lactamase_39,P62593,1.00177,NO,160,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.977,-3.094,2.117,,0.022,,B,0.55,-0.6,0.895,,44.41,BHA,-0.936,0.0495842,0.00193775,1.00177 beta-lactamase_625_R189E,beta-lactamase_625_189,TEM-1,beta-lactamase_625,P62593,1.00177,NO,189,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.844,-2.256,0.412,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.213352,0.0050699,1.00177 beta-lactamase_156_T139N,beta-lactamase_156_139,TEM-1,beta-lactamase_156,P62593,1.00179,NO,139,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.901,-3.686,1.785,,0.216,H,A,0.22,0.39,16.34,16.34,77.62,PPH,-2.04667,0.111618,0.00441837,1.00179 beta-lactamase_2500_L223M,beta-lactamase_2500_223,TEM-1,beta-lactamase_2500,P62593,1.00179,NO,223,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.055,-3.986,2.931,,0.27,,B,0.55,0.09,1.334,,74.48,HHO,-1.35033,0.361275,0.00372793,1.00179 beta-lactamase_39_M270C,beta-lactamase_39_270,TEM-1,beta-lactamase_39,P62593,1.00179,NO,270,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.0495842,0.00767762,1.00179 kka2_1:1_A176A,kka2_1:1_176,Kka2,kka2_1:1,P00552,1.00179,NO,176,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.621,-1.621,,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.520039,0.0083587,1.00179 kka2_1:8_L107C,kka2_1:8_107,Kka2,kka2_1:8,P00552,1.00179,NO,107,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.238,-4.827,3.589,,0.197,.,B,0.55,-1.1,4.478,,71.59,BHH,-2.143,0.100394,0.00561937,1.00179 kka2_1:8_L107C,kka2_1:8_107,Kka2,kka2_1:8,P00552,1.00179,NO,107,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.238,-4.827,3.589,,0.197,.,B,0.55,-1.1,4.478,,71.59,BHH,-2.143,0.100394,0.00561937,1.00179 beta-lactamase_2500_P255A,beta-lactamase_2500_255,TEM-1,beta-lactamase_2500,P62593,1.0018,NO,255,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.361275,0.00499612,1.0018 beta-lactamase_39_S80L,beta-lactamase_39_80,TEM-1,beta-lactamase_39,P62593,1.0018,NO,80,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.029,-2.857,0.828,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.0495842,0.00565569,1.0018 beta-lactamase_625_K30R,beta-lactamase_625_30,TEM-1,beta-lactamase_625,P62593,1.0018,NO,30,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-2.307,-2.265,-0.042,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.213352,0.00448593,1.0018 PSD95pdz3_E331F,PSD95pdz3_331,PSD95pdz3,PSD95pdz3,P31016,1.0018,NO,331,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.404,-3.974,2.57,5.86289,,,,,51.8889,,,,OAA,-1.22533,0.0758425,0.000950134,1.0018 beta-lactamase_2500_D36T,beta-lactamase_2500_36,TEM-1,beta-lactamase_2500,P62593,1.00181,NO,36,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.732,-2.57,-0.162,,0.555,H,A,0.75,1.17,2.26,,77.62,AAP,-1.91167,0.361275,0.00476483,1.00181 beta-lactamase_156_L47E,beta-lactamase_156_47,TEM-1,beta-lactamase_156,P62593,1.00182,NO,47,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.876,-2.999,1.123,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.111618,0.00439844,1.00182 beta-lactamase_39_K286E,beta-lactamase_39_286,TEM-1,beta-lactamase_39,P62593,1.00182,NO,286,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.0495842,,1.00182 kka2_1:8_A14E,kka2_1:8_14,Kka2,kka2_1:8,P00552,1.00182,NO,14,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.837,-3.519,1.682,,0.728,G,A,0.46,0.7,,,71.59,HHH,-1.82567,0.100394,0.00706614,1.00182 kka2_1:8_A14E,kka2_1:8_14,Kka2,kka2_1:8,P00552,1.00182,NO,14,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.837,-3.519,1.682,,0.728,G,A,0.46,0.7,,,71.59,HHH,-1.82567,0.100394,0.00706614,1.00182 beta-lactamase_0_T178H,beta-lactamase_0_178,TEM-1,beta-lactamase_0,P62593,1.00183,NO,178,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-0.791,-4.68,3.889,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.0500837,0.000684366,1.00183 beta-lactamase_156_K254N,beta-lactamase_156_254,TEM-1,beta-lactamase_156,P62593,1.00183,NO,254,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.111618,0.00369,1.00183 beta-lactamase_S221T,beta-lactamase_221,TEM-1,beta-lactamase,P62593,1.00183,NO,221,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.754,-3.292,1.538,5.77407,0.624,H,A,0.74,-0.2,0.383,,74.48,BPH,-1.59967,0.221079,0.0046094,1.00183 kka2_1:8_R253C,kka2_1:8_253,Kka2,kka2_1:8,P00552,1.00183,NO,253,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.356,-3.227,1.871,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.100394,0.0144195,1.00183 kka2_1:8_R253C,kka2_1:8_253,Kka2,kka2_1:8,P00552,1.00183,NO,253,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.356,-3.227,1.871,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.100394,0.0144195,1.00183 Pab1_L191C,Pab1_191,Pab1,Pab1,P04147,1.00183,NO,191,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.2,-4.53,3.33,,0.204,E,B,,2.24,,,,HHP,-1.20133,0.175299,0.000583797,1.00183 beta-lactamase_39_Q88T,beta-lactamase_39_88,TEM-1,beta-lactamase_39,P62593,1.00184,NO,88,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.086,-2.693,0.607,,0.807,,B,0.64,2.03,11.108,11.108,77.62,APH,-1.53433,0.0495842,0.00504167,1.00184 beta-lactamase_156_E272S,beta-lactamase_156_272,TEM-1,beta-lactamase_156,P62593,1.00185,NO,272,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.111618,0.00545371,1.00185 beta-lactamase_156_K144V,beta-lactamase_156_144,TEM-1,beta-lactamase_156,P62593,1.00185,NO,144,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-2.388,-3.003,0.615,,0.863,H,A,2.34,1.27,2.073,,77.62,OBA,-1.904,0.111618,0.00481141,1.00185 beta-lactamase_156_L192A,beta-lactamase_156_192,TEM-1,beta-lactamase_156,P62593,1.00185,NO,192,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.254,-2.317,1.063,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.111618,0.00558728,1.00185 beta-lactamase_2500_S51T,beta-lactamase_2500_51,TEM-1,beta-lactamase_2500,P62593,1.00185,NO,51,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.526,-1.846,0.32,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.361275,0.00504821,1.00185 beta-lactamase_39_D174A,beta-lactamase_39_174,TEM-1,beta-lactamase_39,P62593,1.00185,NO,174,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.738,-3.303,2.565,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.0495842,0.00125633,1.00185 beta-lactamase_39_H287Q,beta-lactamase_39_287,TEM-1,beta-lactamase_39,P62593,1.00185,NO,287,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,,,,,,,,,,,,,BBH,-1.111,0.0495842,,1.00185 beta-lactamase_39_T126Q,beta-lactamase_39_126,TEM-1,beta-lactamase_39,P62593,1.00185,NO,126,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.122,-3.945,2.823,,0.05,H,A,0.22,-0.05,0.586,,44.41,HPH,-1.60467,0.0495842,0.00244552,1.00185 beta-lactamase_625_P224D,beta-lactamase_625_224,TEM-1,beta-lactamase_625,P62593,1.00185,NO,224,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.893,-3.513,2.62,,0.383,,B,0.52,-0.3,1.35,,74.48,HOH,-1.26433,0.213352,0.00189564,1.00185 kka2_1:1_G74G,kka2_1:1_74,Kka2,kka2_1:1,P00552,1.00185,NO,74,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.18,-1.18,,,0.621,T,l,0.75,0.2,15.356,15.356,64.39,POH,-1.91667,0.520039,0.00587035,1.00185 Pab1_L191F,Pab1_191,Pab1,Pab1,P04147,1.00185,NO,191,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.2,-3.51,2.31,,0.204,E,B,,2.24,,,,HHP,-1.20133,0.175299,0.000583797,1.00185 beta-lactamase_156_A246G,beta-lactamase_156_246,TEM-1,beta-lactamase_156,P62593,1.00186,NO,246,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.121,-3.675,1.554,,0.01,E,B,0.46,-1.01,1.959,,73.78,HHH,-1.55633,0.111618,0.00569458,1.00186 beta-lactamase_156_D99K,beta-lactamase_156_99,TEM-1,beta-lactamase_156,P62593,1.00186,NO,99,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.191,-3.447,2.256,,0.402,G,A,0.75,0.36,3.529,,64.69,PAH,-1.794,0.111618,0.00305446,1.00186 beta-lactamase_2500_T269S,beta-lactamase_2500_269,TEM-1,beta-lactamase_2500,P62593,1.00186,NO,269,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.361275,0.00950944,1.00186 beta-lactamase_39_W163V,beta-lactamase_39_163,TEM-1,beta-lactamase_39,P62593,1.00186,NO,163,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-1.843,-3.617,1.774,,0.467,,B,0.47,-0.5,15.095,15.095,63.99,BHA,-1.269,0.0495842,0.00418955,1.00186 beta-lactamase_625_G253I,beta-lactamase_625_253,TEM-1,beta-lactamase_625,P62593,1.00186,NO,253,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.213352,0.00786358,1.00186 beta-lactamase_625_Q267I,beta-lactamase_625_267,TEM-1,beta-lactamase_625,P62593,1.00186,NO,267,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.213352,0.0102128,1.00186 beta-lactamase_625_T112Q,beta-lactamase_625_112,TEM-1,beta-lactamase_625,P62593,1.00186,NO,112,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.186,-3.981,1.795,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.213352,0.00531334,1.00186 Pab1_L190V,Pab1_190,Pab1,Pab1,P04147,1.00186,NO,190,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.325,-2.877,1.552,,0.489,E,B,,2.59,,,,HHH,-1.31033,0.175299,0.00132347,1.00186 beta-lactamase_156_R189L,beta-lactamase_156_189,TEM-1,beta-lactamase_156,P62593,1.00187,NO,189,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.844,-3.611,1.767,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.111618,0.0050699,1.00187 beta-lactamase_156_V157T,beta-lactamase_156_157,TEM-1,beta-lactamase_156,P62593,1.00187,NO,157,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.751,-2.302,0.551,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.111618,0.00506849,1.00187 beta-lactamase_156_V214P,beta-lactamase_156_214,TEM-1,beta-lactamase_156,P62593,1.00187,NO,214,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.299,-3.919,2.62,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.111618,0.00628442,1.00187 beta-lactamase_2500_S80R,beta-lactamase_2500_80,TEM-1,beta-lactamase_2500,P62593,1.00187,NO,80,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.029,-3.076,1.047,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.361275,0.00565569,1.00187 beta-lactamase_625_I261F,beta-lactamase_625_261,TEM-1,beta-lactamase_625,P62593,1.00187,NO,261,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.213352,0.0123091,1.00187 beta-lactamase_625_L73H,beta-lactamase_625_73,TEM-1,beta-lactamase_625,P62593,1.00187,NO,73,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.507,-4.923,3.416,,,H,A,0.55,-0.64,2.933,,67.83,HHH,-1.487,0.213352,0.00488983,1.00187 beta-lactamase_625_W163Y,beta-lactamase_625_163,TEM-1,beta-lactamase_625,P62593,1.00187,NO,163,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-1.843,-3.906,2.063,,0.467,,B,0.47,-0.5,5.019,,63.99,BHA,-1.269,0.213352,0.00418955,1.00187 beta-lactamase_A280N,beta-lactamase_280,TEM-1,beta-lactamase,P62593,1.00187,NO,280,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.708,-3.726,2.018,4.74932,0.379,H,A,0.52,-0.72,1.785,,68.18,OHP,-1.66433,0.221079,0.0530888,1.00187 beta-lactamase_A77N,beta-lactamase_77,TEM-1,beta-lactamase,P62593,1.00187,NO,77,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.234,-3.844,2.61,4.75777,0.039,H,A,0.52,-0.56,1.708,,64.34,OHH,-1.294,0.221079,0.00282362,1.00187 beta-lactamase_D207Q,beta-lactamase_207,TEM-1,beta-lactamase,P62593,1.00187,NO,207,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.064,-2.209,0.145,5.40404,0.409,H,A,0.23,0.12,1.975,,77.62,HAH,-1.77033,0.221079,0.00592942,1.00187 beta-lactamase_D33G,beta-lactamase_33,TEM-1,beta-lactamase,P62593,1.00187,NO,33,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.321,-3.465,1.144,5.05203,0.366,H,A,0.23,0.33,2.032,,77.62,BAH,-2.12133,0.221079,0.00435556,1.00187 beta-lactamase_D36S,beta-lactamase_36,TEM-1,beta-lactamase,P62593,1.00187,NO,36,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.732,-2.107,-0.625,5.39764,0.555,H,A,0.11,1.17,13.689,13.689,77.62,AAP,-1.91167,0.221079,0.00476483,1.00187 beta-lactamase_E119D,beta-lactamase_119,TEM-1,beta-lactamase,P62593,1.00187,NO,119,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.412,-2.093,0.681,5.33349,0.358,H,A,1.52,0.51,1.983,,63.99,BAH,-1.623,0.221079,0.00386966,1.00187 beta-lactamase_E26A,beta-lactamase_26,TEM-1,beta-lactamase,P62593,1.00187,NO,26,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.454,-2.207,-0.247,,0.54,H,A,1.04,0.98,,,93.01,OAP,-1.96167,0.221079,0.00297948,1.00187 beta-lactamase_E46T,beta-lactamase_46,TEM-1,beta-lactamase,P62593,1.00187,NO,46,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.94,-3.517,1.577,5.36461,0.021,E,B,1.51,0.14,0.373,,59.44,HAH,-2.079,0.221079,0.00427568,1.00187 beta-lactamase_G216Q,beta-lactamase_216,TEM-1,beta-lactamase,P62593,1.00187,NO,216,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.477,-3.862,2.385,4.91694,0.437,I,A,0.23,-0.58,1.718,,74.48,HOO,-1.68067,0.221079,0.00639568,1.00187 beta-lactamase_I206W,beta-lactamase_206,TEM-1,beta-lactamase,P62593,1.00187,NO,206,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-2.429,-5.397,2.968,5.3727,0.173,H,A,1,-0.34,2.061,,77.62,HHA,-1.805,0.221079,0.00528934,1.00187 beta-lactamase_L111M,beta-lactamase_111,TEM-1,beta-lactamase,P62593,1.00187,NO,111,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.76,-4.22,2.46,5.8705,0.328,T,A,0.84,0.93,3.836,,64.34,BHP,-1.884,0.221079,0.00480671,1.00187 beta-lactamase_L196F,beta-lactamase_196,TEM-1,beta-lactamase,P62593,1.00187,NO,196,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-2.478,-4.226,1.748,,0.518,S,A,0.55,1.35,,,77.62,AHH,-1.839,0.221079,0.00512144,1.00187 beta-lactamase_L49V,beta-lactamase_49,TEM-1,beta-lactamase,P62593,1.00187,NO,49,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.897,-2.549,0.652,5.86005,0.131,T,A,1.3,0.04,3.112,,64.69,AHP,-1.99233,0.221079,0.00401477,1.00187 beta-lactamase_Q203N,beta-lactamase_203,TEM-1,beta-lactamase,P62593,1.00187,NO,203,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.168,-3.727,1.559,5.65296,0.47,H,A,0.12,-0.38,1.66,,65.38,BPP,-1.614,0.221079,0.00631514,1.00187 beta-lactamase_Q274E,beta-lactamase_274,TEM-1,beta-lactamase,P62593,1.00187,NO,274,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.082,-3.385,1.303,5.6671,0.066,H,A,0.11,-0.27,2.354,,64.69,BPH,-1.931,0.221079,0.0110418,1.00187 beta-lactamase_Q86D,beta-lactamase_86,TEM-1,beta-lactamase,P62593,1.00187,NO,86,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.4,-2.27,-0.13,5.39897,0.696,S,A,0.12,2.38,2.105,,77.62,OPA,-1.61067,0.221079,0.00450027,1.00187 beta-lactamase_S122K,beta-lactamase_122,TEM-1,beta-lactamase,P62593,1.00187,NO,122,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.406,-3.55,1.144,4.87767,0.352,H,A,0.73,-0.54,1.581,,77.62,OPH,-1.39767,0.221079,0.00497825,1.00187 beta-lactamase_S254E,beta-lactamase_254,TEM-1,beta-lactamase,P62593,1.00187,NO,254,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.126,-2.12,-0.006,5.49575,0.312,,a,0.25,-0.48,24.91,24.91,69.58,OPB,-2.215,0.221079,0.00369,1.00187 beta-lactamase_S281H,beta-lactamase_281,TEM-1,beta-lactamase,P62593,1.00187,NO,281,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.247,-4.83,2.583,4.73591,0.128,H,A,0.25,-0.26,2.144,,77.62,HPH,-1.847,0.221079,0.0406482,1.00187 beta-lactamase_S2Q,beta-lactamase_2,TEM-1,beta-lactamase,P62593,1.00187,NO,2,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.942,-3.83,1.888,,,,,,,2.36,,65.38,HPH,-2.02767,0.221079,0.00227352,1.00187 beta-lactamase_T112A,beta-lactamase_112,TEM-1,beta-lactamase,P62593,1.00187,NO,112,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.186,-1.933,-0.253,6.47162,0.921,T,A,0.77,1.06,2.04,,73.78,HPA,-1.925,0.221079,0.00531334,1.00187 beta-lactamase_T139Q,beta-lactamase_139,TEM-1,beta-lactamase,P62593,1.00187,NO,139,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.901,-2.8,0.899,5.69095,0.216,H,A,0.3,0.39,2.256,,77.62,PPH,-2.04667,0.221079,0.00441837,1.00187 beta-lactamase_V31C,beta-lactamase_31,TEM-1,beta-lactamase,P62593,1.00187,NO,31,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.822,-3.252,1.43,5.43781,,H,A,2.78,-0.46,2.885,,73.78,BHB,-2.03767,0.221079,0.00478065,1.00187 kka2_1:8_P98Q,kka2_1:8_98,Kka2,kka2_1:8,P00552,1.00187,NO,98,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.526,-3.169,1.643,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.100394,0.00622754,1.00187 kka2_1:8_P98Q,kka2_1:8_98,Kka2,kka2_1:8,P00552,1.00187,NO,98,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.526,-3.169,1.643,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.100394,0.00622754,1.00187 Pab1_E174T,Pab1_174,Pab1,Pab1,P04147,1.00187,NO,174,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.422,-3.37,1.948,,0.578,S,A,,0.38,,,,HAA,-1.65133,0.175299,0.00077863,1.00187 beta-lactamase_156_M180Y,beta-lactamase_156_180,TEM-1,beta-lactamase_156,P62593,1.00188,NO,180,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-2.795,-2.93,0.135,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.111618,0.00552048,1.00188 beta-lactamase_625_L196P,beta-lactamase_625_196,TEM-1,beta-lactamase_625,P62593,1.00188,NO,196,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-2.478,-3.165,0.687,,0.518,S,A,0.55,1.35,12.152,12.152,77.62,AHH,-1.839,0.213352,0.00512144,1.00188 hsp90_E590E,hsp90_590,hsp90,hsp90,P02829,1.00188,NO,590,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.818,-2.818,,4.65049,0.021,H,A,,0.03,,,,HAO,-3.338,0.368192,0.000222939,1.00188 beta-lactamase_156_E119D,beta-lactamase_156_119,TEM-1,beta-lactamase_156,P62593,1.00189,NO,119,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.412,-2.093,0.681,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.111618,0.00386966,1.00189 beta-lactamase_156_L219M,beta-lactamase_156_219,TEM-1,beta-lactamase_156,P62593,1.00189,NO,219,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.313,-3.006,1.693,,,I,A,0.55,-0.51,2.321,,74.48,HHB,-1.21533,0.111618,0.00664345,1.00189 beta-lactamase_39_L100M,beta-lactamase_39_100,TEM-1,beta-lactamase_39,P62593,1.00189,NO,100,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.218,-4.039,2.821,,0.343,,B,0.55,0.13,8.311,,63.29,AHH,-1.23467,0.0495842,0.00413885,1.00189 beta-lactamase_39_G141I,beta-lactamase_39_141,TEM-1,beta-lactamase_39,P62593,1.0019,NO,141,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.828,-4.236,3.408,,0.575,T,l,0.29,-0.28,0.722,,64.69,HOO,-1.08933,0.0495842,0.0012419,1.0019 beta-lactamase_625_E238V,beta-lactamase_625_238,TEM-1,beta-lactamase_625,P62593,1.0019,NO,238,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.213352,0.00743256,1.0019 beta-lactamase_625_N50Y,beta-lactamase_625_50,TEM-1,beta-lactamase_625,P62593,1.0019,NO,50,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-2.979,-4.3,1.321,,0.912,T,A,0.61,1.24,3.446,,77.62,HPP,-2.134,0.213352,0.0047211,1.0019 kka2_1:8_G6C,kka2_1:8_6,Kka2,kka2_1:8,P00552,1.0019,NO,6,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.685,-2.485,0.8,,,,,,,,,71.59,AOH,-1.639,0.100394,0.00204693,1.0019 kka2_1:8_G6C,kka2_1:8_6,Kka2,kka2_1:8,P00552,1.0019,NO,6,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.685,-2.485,0.8,,,,,,,,,71.59,AOH,-1.639,0.100394,0.00204693,1.0019 PSD95pdz3_K393T,PSD95pdz3_393,PSD95pdz3,PSD95pdz3,P31016,1.0019,NO,393,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.416,-3.103,1.687,5.42682,,,,,22.0122,,,,HBO,-1.4265,0.0758425,0.000879298,1.0019 beta-lactamase_156_I244E,beta-lactamase_156_244,TEM-1,beta-lactamase_156,P62593,1.00191,NO,244,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.555,-3.795,2.24,,,E,B,0.48,-0.84,1.325,,77.62,OHH,-1.385,0.111618,0.00605379,1.00191 beta-lactamase_39_D174W,beta-lactamase_39_174,TEM-1,beta-lactamase_39,P62593,1.00191,NO,174,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.738,-5.547,4.809,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.0495842,0.00125633,1.00191 beta-lactamase_625_H156D,beta-lactamase_625_156,TEM-1,beta-lactamase_625,P62593,1.00191,NO,156,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-3.156,-2.458,-0.698,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.213352,0.00468596,1.00191 Pab1_G193D,Pab1_193,Pab1,Pab1,P04147,1.00191,NO,193,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.414,-1.736,0.322,,,,,,,,,,POP,-1.55733,0.175299,0.0014922,1.00191 Pab1_P200A,Pab1_200,Pab1,Pab1,P04147,1.00191,NO,200,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.871,-2.388,0.517,,,,,,,3.877,,80.59,HOO,-1.7005,0.175299,0.00190795,1.00191 beta-lactamase_156_G39L,beta-lactamase_156_39,TEM-1,beta-lactamase_156,P62593,1.00192,NO,39,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.864,-3.751,1.887,,0.701,T,L,0.29,0.47,1.454,,77.62,HOH,-1.53633,0.111618,0.00487611,1.00192 beta-lactamase_156_L73G,beta-lactamase_156_73,TEM-1,beta-lactamase_156,P62593,1.00192,NO,73,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.507,-3.739,2.232,,,H,A,0.55,-0.64,2.09,,67.83,HHH,-1.487,0.111618,0.00488983,1.00192 beta-lactamase_2500_T112W,beta-lactamase_2500_112,TEM-1,beta-lactamase_2500,P62593,1.00192,NO,112,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.186,-5.474,3.288,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.361275,0.00531334,1.00192 beta-lactamase_39_A123T,beta-lactamase_39_123,TEM-1,beta-lactamase_39,P62593,1.00192,NO,123,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.834,-3.222,2.388,,0.039,H,A,0.46,-0.72,0.705,,41.26,PHH,-1.47367,0.0495842,0.0010157,1.00192 beta-lactamase_39_N274G,beta-lactamase_39_274,TEM-1,beta-lactamase_39,P62593,1.00192,NO,274,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.0495842,0.0110418,1.00192 kka2_1:1_A172A,kka2_1:1_172,Kka2,kka2_1:1,P00552,1.00192,NO,172,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.757,-1.757,,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.520039,0.0079265,1.00192 beta-lactamase_156_A77C,beta-lactamase_156_77,TEM-1,beta-lactamase_156,P62593,1.00194,NO,77,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.234,-4.708,3.474,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.111618,0.00282362,1.00194 beta-lactamase_156_L55S,beta-lactamase_156_55,TEM-1,beta-lactamase_156,P62593,1.00194,NO,55,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.86,-3.706,1.846,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.111618,0.00403741,1.00194 beta-lactamase_2500_K32H,beta-lactamase_2500_32,TEM-1,beta-lactamase_2500,P62593,1.00194,NO,32,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.984,-4.632,2.648,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.361275,0.00401283,1.00194 beta-lactamase_39_L47H,beta-lactamase_39_47,TEM-1,beta-lactamase_39,P62593,1.00194,NO,47,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.876,-2.811,0.935,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.0495842,0.00439844,1.00194 beta-lactamase_156_T112S,beta-lactamase_156_112,TEM-1,beta-lactamase_156,P62593,1.00195,NO,112,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.186,-2.762,0.576,,0.921,T,A,0.22,1.06,2.87,,73.78,HPA,-1.925,0.111618,0.00531334,1.00195 kka2_1:8_C192S,kka2_1:8_192,Kka2,kka2_1:8,P00552,1.00195,NO,192,C,S,CS,Special,Polar,5.07,5.68,0.61,112,121,105,-16,108.5,89,-19.5,-1.067,-2.445,1.378,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.100394,0.00485428,1.00195 kka2_1:8_C192S,kka2_1:8_192,Kka2,kka2_1:8,P00552,1.00195,NO,192,C,S,CS,Special,Polar,5.07,5.68,0.61,112,121,105,-16,108.5,89,-19.5,-1.067,-2.445,1.378,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.100394,0.00485428,1.00195 beta-lactamase_156_A211K,beta-lactamase_156_211,TEM-1,beta-lactamase_156,P62593,1.00196,NO,211,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.896,-3.538,1.642,,0.369,T,A,0.46,-0.69,8.527,8.527,77.62,AHA,-1.94633,0.111618,0.00648183,1.00196 beta-lactamase_156_V259Y,beta-lactamase_156_259,TEM-1,beta-lactamase_156,P62593,1.00196,NO,259,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.111618,0.0070773,1.00196 beta-lactamase_39_Q276R,beta-lactamase_39_276,TEM-1,beta-lactamase_39,P62593,1.00196,NO,276,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.0495842,0.0191712,1.00196 beta-lactamase_0_C75Q,beta-lactamase_0_75,TEM-1,beta-lactamase_0,P62593,1.00197,NO,75,C,Q,CQ,Special,Polar,5.07,6.24429,1.17429,154,121,146,25,108.5,143.8,35.3,-1.245,-4.228,2.983,,,H,A,0.46,-0.87,2.256,,50,HOO,-1.24333,0.0500837,0.0034616,1.00197 beta-lactamase_39_A183V,beta-lactamase_39_183,TEM-1,beta-lactamase_39,P62593,1.00197,NO,183,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.231,-3.28,2.049,,0.155,H,A,0.46,-0.91,1.237,,77.62,HHH,-1.53367,0.0495842,0.00296631,1.00197 beta-lactamase_625_G226Y,beta-lactamase_625_226,TEM-1,beta-lactamase_625,P62593,1.00197,NO,226,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.461,-4.462,3.001,,0.701,T,l,0.29,-0.25,3.199,,74.48,HOH,-1.42933,0.213352,0.00665294,1.00197 WW_domain_R187L,WW_domain_187,Yap65,WW_domain,P46937,1.00197,NO,187,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.402,-3.198,1.796,5.05189,,,,,,3.431,,78.57,PBH,-1.362,0.153962,0.00171149,1.00197 beta-lactamase_156_Y44V,beta-lactamase_156_44,TEM-1,beta-lactamase_156,P62593,1.00198,NO,44,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-2.547,-1.805,-0.742,,,E,B,0.21,-0.45,2.184,,73.78,OHH,-1.86267,0.111618,0.00426364,1.00198 beta-lactamase_625_A215G,beta-lactamase_625_215,TEM-1,beta-lactamase_625,P62593,1.00198,NO,215,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.503,-1.579,0.076,,,,a,0.46,-0.93,3.583,,74.48,HHO,-1.42633,0.213352,0.00544007,1.00198 beta-lactamase_625_G194H,beta-lactamase_625_194,TEM-1,beta-lactamase_625,P62593,1.00199,NO,194,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.396,-4.628,3.232,,0.276,S,b,0.29,0.36,3.593,,67.83,POA,-1.832,0.213352,0.00392163,1.00199 beta-lactamase_625_M67S,beta-lactamase_625_67,TEM-1,beta-lactamase_625,P62593,1.00199,NO,67,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-2.231,-2.445,0.214,,0.006,G,P,0.55,-0.81,2.653,,65.03,HHP,-1.502,0.213352,0.00409753,1.00199 Pab1_N162L,Pab1_162,Pab1,Pab1,P04147,1.00199,NO,162,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-2.313,-2.383,0.07,,0.681,T,A,,1.12,,,,APO,-1.532,0.175299,0.0030719,1.00199 beta-lactamase_156_G85Q,beta-lactamase_156_85,TEM-1,beta-lactamase_156,P62593,1.002,NO,85,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.011,-3.928,2.917,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.111618,0.00252173,1.002 beta-lactamase_2500_H94K,beta-lactamase_2500_94,TEM-1,beta-lactamase_2500,P62593,1.002,NO,94,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-2.5,-2.567,0.067,,0.776,,B,0.17,1.24,1.176,,77.62,HBH,-1.872,0.361275,0.00389226,1.002 beta-lactamase_39_G253R,beta-lactamase_39_253,TEM-1,beta-lactamase_39,P62593,1.002,NO,253,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.0495842,0.00786358,1.002 beta-lactamase_39_L47A,beta-lactamase_39_47,TEM-1,beta-lactamase_39,P62593,1.002,NO,47,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.876,-3.301,1.425,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.0495842,0.00439844,1.002 beta-lactamase_625_A148C,beta-lactamase_625_148,TEM-1,beta-lactamase_625,P62593,1.002,NO,148,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.757,-5.042,3.285,,0.379,H,A,0.46,-0.55,1.359,,72.73,PHH,-1.40167,0.213352,0.00547053,1.002 beta-lactamase_625_S221Q,beta-lactamase_625_221,TEM-1,beta-lactamase_625,P62593,1.002,NO,221,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.754,-3.871,2.117,,0.624,H,A,0.27,-0.2,1.495,,74.48,BPH,-1.59967,0.213352,0.0046094,1.002 beta-lactamase_156_K286L,beta-lactamase_156_286,TEM-1,beta-lactamase_156,P62593,1.00201,NO,286,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.111618,,1.00201 beta-lactamase_39_N168E,beta-lactamase_39_168,TEM-1,beta-lactamase_39,P62593,1.00201,NO,168,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-1.029,-3.29,2.261,,0.113,G,A,0.61,-0.4,0.822,,44.41,HPA,-1.13233,0.0495842,0.00288667,1.00201 beta-lactamase_156_H24Q,beta-lactamase_156_24,TEM-1,beta-lactamase_156,P62593,1.00202,NO,24,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-2.481,-2.604,0.123,,,,,,,2.708,,93.01,OBO,-2.0035,0.111618,0.00238894,1.00202 beta-lactamase_156_T193Y,beta-lactamase_156_193,TEM-1,beta-lactamase_156,P62593,1.00202,NO,193,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.914,-3.989,2.075,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.111618,0.00482669,1.00202 beta-lactamase_39_K190G,beta-lactamase_39_190,TEM-1,beta-lactamase_39,P62593,1.00202,NO,190,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.994,-3.44,1.446,,0.371,H,A,2.34,0.16,1.513,,77.62,BBH,-1.64167,0.0495842,0.00574527,1.00202 beta-lactamase_39_L137S,beta-lactamase_39_137,TEM-1,beta-lactamase_39,P62593,1.00202,NO,137,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.03,-3.64,2.61,,,H,A,0.55,-0.38,0.674,,42.31,HHP,-1.58933,0.0495842,0.00278599,1.00202 beta-lactamase_0_L79H,beta-lactamase_0_79,TEM-1,beta-lactamase_0,P62593,1.00203,NO,79,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.842,-4.903,4.061,,0.007,H,A,0.55,-0.16,5.053,,50.35,HHP,-1.44333,0.0500837,0.000947397,1.00203 beta-lactamase_156_L28E,beta-lactamase_156_28,TEM-1,beta-lactamase_156,P62593,1.00203,NO,28,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.579,-3.677,2.098,,0.277,H,A,0.55,-0.16,3.262,,93.01,PHH,-2.11333,0.111618,0.00359321,1.00203 beta-lactamase_156_P250H,beta-lactamase_156_250,TEM-1,beta-lactamase_156,P62593,1.00203,NO,250,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.111618,0.00550899,1.00203 beta-lactamase_39_P172Q,beta-lactamase_39_172,TEM-1,beta-lactamase_39,P62593,1.00203,NO,172,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.998,-3.965,2.967,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.0495842,0.00312594,1.00203 beta-lactamase_156_R189G,beta-lactamase_156_189,TEM-1,beta-lactamase_156,P62593,1.00204,NO,189,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.844,-3.504,1.66,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.111618,0.0050699,1.00204 beta-lactamase_156_S201F,beta-lactamase_156_201,TEM-1,beta-lactamase_156,P62593,1.00204,NO,201,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.183,-4.138,2.955,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.111618,0.00198815,1.00204 beta-lactamase_39_L89Y,beta-lactamase_39_89,TEM-1,beta-lactamase_39,P62593,1.00204,NO,89,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.096,-4.101,3.005,,0.168,T,A,0.55,0.63,3.233,,64.34,PHO,-1.75767,0.0495842,0.00207068,1.00204 beta-lactamase_625_D207C,beta-lactamase_625_207,TEM-1,beta-lactamase_625,P62593,1.00204,NO,207,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.064,-5.19,3.126,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.213352,0.00592942,1.00204 beta-lactamase_625_A282Y,beta-lactamase_625_282,TEM-1,beta-lactamase_625,P62593,1.00205,NO,282,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.213352,0.0449821,1.00205 beta-lactamase_625_N168A,beta-lactamase_625_168,TEM-1,beta-lactamase_625,P62593,1.00205,NO,168,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-1.029,-3.17,2.141,,0.113,G,A,0.61,-0.4,1.014,,44.41,HPA,-1.13233,0.213352,0.00288667,1.00205 beta-lactamase_156_A148R,beta-lactamase_156_148,TEM-1,beta-lactamase_156,P62593,1.00206,NO,148,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.757,-2.456,0.699,,0.379,H,A,0.46,-0.55,3.551,,72.73,PHH,-1.40167,0.111618,0.00547053,1.00206 beta-lactamase_156_L135A,beta-lactamase_156_135,TEM-1,beta-lactamase_156,P62593,1.00206,NO,135,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.002,-3.131,2.129,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.111618,0.00244423,1.00206 beta-lactamase_156_N173C,beta-lactamase_156_173,TEM-1,beta-lactamase_156,P62593,1.00206,NO,173,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-2.663,-5.092,2.429,,1.044,T,l,0.61,1.25,3.718,,77.62,OPA,-1.46633,0.111618,0.0033769,1.00206 beta-lactamase_625_E35Q,beta-lactamase_625_35,TEM-1,beta-lactamase_625,P62593,1.00206,NO,35,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-0.869,-3.292,2.423,,0.15,H,A,1.04,0.21,0.664,,46.85,HAA,-1.88667,0.213352,0.00174441,1.00206 beta-lactamase_625_P172M,beta-lactamase_625_172,TEM-1,beta-lactamase_625,P62593,1.00206,NO,172,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.998,-4.616,3.618,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.213352,0.00312594,1.00206 beta-lactamase_2500_E108D,beta-lactamase_2500_108,TEM-1,beta-lactamase_2500,P62593,1.00207,NO,108,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.46,-2.67,1.21,,0.572,G,A,1.04,1.87,1.147,,72.73,PAB,-1.437,0.361275,0.00413372,1.00207 beta-lactamase_39_V157F,beta-lactamase_39_157,TEM-1,beta-lactamase_39,P62593,1.00207,NO,157,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.751,-3.968,2.217,,0.308,S,a,0.44,-0.75,10.364,10.364,69.58,BHP,-2.00767,0.0495842,0.00506849,1.00207 beta-lactamase_625_C75A,beta-lactamase_625_75,TEM-1,beta-lactamase_625,P62593,1.00207,NO,75,C,A,CA,Special,Hydrophobic,5.07,6,0.93,195,121,89,-32,108.5,88.6,-19.9,-1.245,-1.87,0.625,,,H,A,0.46,-0.87,2.141,,50,HOO,-1.24333,0.213352,0.0034616,1.00207 beta-lactamase_156_T193M,beta-lactamase_156_193,TEM-1,beta-lactamase_156,P62593,1.00208,NO,193,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.914,-4.362,2.448,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.111618,0.00482669,1.00208 beta-lactamase_2500_H151I,beta-lactamase_2500_151,TEM-1,beta-lactamase_2500,P62593,1.00208,NO,151,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-2.96,-4.091,1.131,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.361275,0.00216946,1.00208 beta-lactamase_39_E272H,beta-lactamase_39_272,TEM-1,beta-lactamase_39,P62593,1.00208,NO,272,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.127,,,,0.081,H,A,0.43,-0.97,12.983,12.983,63.64,AAB,-1.56333,0.0495842,0.00545371,1.00208 beta-lactamase_39_G226Q,beta-lactamase_39_226,TEM-1,beta-lactamase_39,P62593,1.00208,NO,226,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.461,-3.959,2.498,,0.701,T,l,0.29,-0.25,23.034,23.034,74.48,HOH,-1.42933,0.0495842,0.00665294,1.00208 beta-lactamase_39_G226T,beta-lactamase_39_226,TEM-1,beta-lactamase_39,P62593,1.00208,NO,226,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.461,-3.599,2.138,,0.701,T,l,0.29,-0.25,23.034,23.034,74.48,HOH,-1.42933,0.0495842,0.00665294,1.00208 beta-lactamase_V78V,beta-lactamase_78,TEM-1,beta-lactamase,P62593,1.00208,NO,78,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.459,-1.459,,4.79197,,H,A,0.96,-0.47,1.132,,63.64,HHH,-1.17833,0.221079,0.00492501,1.00208 beta-lactamase_156_D99G,beta-lactamase_156_99,TEM-1,beta-lactamase_156,P62593,1.00209,NO,99,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.191,-3.32,2.129,,0.402,G,A,0.75,0.36,3.529,,64.69,PAH,-1.794,0.111618,0.00305446,1.00209 beta-lactamase_156_L73I,beta-lactamase_156_73,TEM-1,beta-lactamase_156,P62593,1.00209,NO,73,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.507,-2.52,1.013,,,H,A,0.55,-0.64,2.09,,67.83,HHH,-1.487,0.111618,0.00488983,1.00209 beta-lactamase_156_L73M,beta-lactamase_156_73,TEM-1,beta-lactamase_156,P62593,1.00209,NO,73,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.507,-2.898,1.391,,,H,A,0.55,-0.64,2.09,,67.83,HHH,-1.487,0.111618,0.00488983,1.00209 beta-lactamase_2500_I171R,beta-lactamase_2500_171,TEM-1,beta-lactamase_2500,P62593,1.00209,NO,171,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-2.431,-2.473,0.042,,0.361,,B,0.48,0.53,1.66,,77.62,HHO,-1.55533,0.361275,0.00623355,1.00209 beta-lactamase_625_S96G,beta-lactamase_625_96,TEM-1,beta-lactamase_625,P62593,1.00209,NO,96,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.27,-2.481,0.211,,0.368,,b,0.27,0.39,5.244,,73.78,HPP,-2.019,0.213352,0.00551835,1.00209 beta-lactamase_156_T264Y,beta-lactamase_156_264,TEM-1,beta-lactamase_156,P62593,1.0021,NO,264,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.111618,0.0119399,1.0021 beta-lactamase_39_R189H,beta-lactamase_39_189,TEM-1,beta-lactamase_39,P62593,1.0021,NO,189,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.844,-2.544,0.7,,0.278,H,A,1.2,1.01,12.11,12.11,72.73,HBB,-1.668,0.0495842,0.0050699,1.0021 kka2_1:2_P179I,kka2_1:2_179,Kka2,kka2_1:2,P00552,1.0021,NO,179,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.974,-3.795,2.821,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.295029,0.00298346,1.0021 beta-lactamase_156_L199I,beta-lactamase_156_199,TEM-1,beta-lactamase_156,P62593,1.00211,NO,199,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-2.942,-3.16,0.218,,0.832,H,A,0.55,0.42,1.552,,77.62,PHH,-2.32933,0.111618,0.0048649,1.00211 beta-lactamase_2500_E102P,beta-lactamase_2500_102,TEM-1,beta-lactamase_2500,P62593,1.00211,NO,102,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.118,-3.88,1.762,,0.722,S,B,1.04,1.82,1.336,,73.08,HAH,-1.581,0.361275,0.00486633,1.00211 beta-lactamase_2500_H151K,beta-lactamase_2500_151,TEM-1,beta-lactamase_2500,P62593,1.00211,NO,151,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-2.96,-3.032,0.072,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.361275,0.00216946,1.00211 beta-lactamase_39_L100C,beta-lactamase_39_100,TEM-1,beta-lactamase_39,P62593,1.00211,NO,100,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.218,-4.758,3.54,,0.343,,B,0.55,0.13,8.311,,63.29,AHH,-1.23467,0.0495842,0.00413885,1.00211 beta-lactamase_39_T116G,beta-lactamase_39_116,TEM-1,beta-lactamase_39,P62593,1.00211,NO,116,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.28,-3.287,2.007,,0.115,E,B,0.22,-0.12,1.133,,67.48,HPH,-1.39967,0.0495842,0.00336175,1.00211 beta-lactamase_625_G216T,beta-lactamase_625_216,TEM-1,beta-lactamase_625,P62593,1.00211,NO,216,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.477,-3.599,2.122,,0.437,I,A,0.29,-0.58,1.718,,74.48,HOO,-1.68067,0.213352,0.00639568,1.00211 PSD95pdz3_P346M,PSD95pdz3_346,PSD95pdz3,PSD95pdz3,P31016,1.00211,NO,346,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.236,-4.387,3.151,5.02406,,,,,14.6629,,,,OOH,-1.18367,0.0758425,0.000758563,1.00211 beta-lactamase_156_E210L,beta-lactamase_156_210,TEM-1,beta-lactamase_156,P62593,1.00212,NO,210,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.319,-2.05,-0.269,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.111618,0.00663582,1.00212 beta-lactamase_156_R239A,beta-lactamase_156_239,TEM-1,beta-lactamase_156,P62593,1.00212,NO,239,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.111618,0.00213852,1.00212 beta-lactamase_156_T269I,beta-lactamase_156_269,TEM-1,beta-lactamase_156,P62593,1.00212,NO,269,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.111618,0.00950944,1.00212 beta-lactamase_39_L55Y,beta-lactamase_39_55,TEM-1,beta-lactamase_39,P62593,1.00212,NO,55,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.86,-3.812,1.952,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.0495842,0.00403741,1.00212 beta-lactamase_625_S266T,beta-lactamase_625_266,TEM-1,beta-lactamase_625,P62593,1.00212,NO,266,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.213352,0.0140785,1.00212 beta-lactamase_39_M127K,beta-lactamase_39_127,TEM-1,beta-lactamase_39,P62593,1.00213,NO,127,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-2.251,-3,0.749,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.0495842,0.00437927,1.00213 beta-lactamase_39_R159T,beta-lactamase_39_159,TEM-1,beta-lactamase_39,P62593,1.00213,NO,159,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-0.94,-3.47,2.53,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.0495842,0.00108472,1.00213 beta-lactamase_625_F149L,beta-lactamase_625_149,TEM-1,beta-lactamase_625,P62593,1.00213,NO,149,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.299,-3.137,1.838,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.213352,0.00418462,1.00213 beta-lactamase_E175Y,beta-lactamase_175,TEM-1,beta-lactamase,P62593,1.00213,NO,175,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.336,-4.303,1.967,6.0311,0.551,,A,0.75,1.05,5.316,,77.62,AAB,-1.31233,0.221079,0.00482205,1.00213 beta-lactamase_2500_K109R,beta-lactamase_2500_109,TEM-1,beta-lactamase_2500,P62593,1.00214,NO,109,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.734,-2.595,0.861,,0.787,G,A,2.34,2.21,0.998,,72.73,ABB,-1.63333,0.361275,0.00462493,1.00214 beta-lactamase_625_N98H,beta-lactamase_625_98,TEM-1,beta-lactamase_625,P62593,1.00214,NO,98,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-2.973,-3.344,0.371,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.213352,0.00505389,1.00214 beta-lactamase_625_P224S,beta-lactamase_625_224,TEM-1,beta-lactamase_625,P62593,1.00214,NO,224,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.893,-2.58,1.687,,0.383,,B,0.52,-0.3,1.35,,74.48,HOH,-1.26433,0.213352,0.00189564,1.00214 kka2_1:2_T85R,kka2_1:2_85,Kka2,kka2_1:2,P00552,1.00214,NO,85,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.165,-2.814,0.649,,0.576,E,B,0.22,1.39,1.853,,71.59,HPA,-2.10133,0.295029,0.00634493,1.00214 beta-lactamase_39_S51W,beta-lactamase_39_51,TEM-1,beta-lactamase_39,P62593,1.00215,NO,51,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.526,-5.435,3.909,,0.496,T,A,0.27,0.26,2.964,,72.73,PPO,-1.88467,0.0495842,0.00504821,1.00215 beta-lactamase_625_D36F,beta-lactamase_625_36,TEM-1,beta-lactamase_625,P62593,1.00215,NO,36,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.732,-4.318,1.586,,0.555,H,A,0.75,1.17,2.26,,77.62,AAP,-1.91167,0.213352,0.00476483,1.00215 beta-lactamase_625_L196I,beta-lactamase_625_196,TEM-1,beta-lactamase_625,P62593,1.00215,NO,196,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-2.478,-2.648,0.17,,0.518,S,A,0.55,1.35,12.152,12.152,77.62,AHH,-1.839,0.213352,0.00512144,1.00215 beta-lactamase_T198S,beta-lactamase_198,TEM-1,beta-lactamase,P62593,1.00215,NO,198,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.168,-1.471,-0.697,4.9209,0.489,,B,0.69,-0.13,0.37,,73.78,HPH,-1.98767,0.221079,0.004311,1.00215 Pab1_F168F,Pab1_168,Pab1,Pab1,P04147,1.00215,NO,168,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.269,-1.269,,,,,,,,0.789,,56.33,OHO,-1.10033,0.175299,0.00064061,1.00215 beta-lactamase_0_M209P,beta-lactamase_0_209,TEM-1,beta-lactamase_0,P62593,1.00216,NO,209,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.442,-4.077,2.635,,,H,A,0.55,-0.97,3.876,,64.69,HHA,-1.52633,0.0500837,0.00625021,1.00216 beta-lactamase_156_F58R,beta-lactamase_156_58,TEM-1,beta-lactamase_156,P62593,1.00216,NO,58,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-2.914,-2.758,-0.156,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.111618,0.00523369,1.00216 beta-lactamase_2500_Q267A,beta-lactamase_2500_267,TEM-1,beta-lactamase_2500,P62593,1.00216,NO,267,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.361275,0.0102128,1.00216 beta-lactamase_39_R63P,beta-lactamase_39_63,TEM-1,beta-lactamase_39,P62593,1.00216,NO,63,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-0.943,-3.929,2.986,,0.218,,B,1.2,-0.31,0.326,,44.06,ABH,-0.992333,0.0495842,0.00126938,1.00216 beta-lactamase_156_L49Y,beta-lactamase_156_49,TEM-1,beta-lactamase_156,P62593,1.00217,NO,49,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.897,-4.158,2.261,,0.131,T,A,0.55,0.04,3.112,,64.69,AHP,-1.99233,0.111618,0.00401477,1.00217 beta-lactamase_156_R159M,beta-lactamase_156_159,TEM-1,beta-lactamase_156,P62593,1.00217,NO,159,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-0.94,-4.529,3.589,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.111618,0.00108472,1.00217 beta-lactamase_39_V72H,beta-lactamase_39_72,TEM-1,beta-lactamase_39,P62593,1.00217,NO,72,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.658,-4.908,3.25,,,H,A,0.44,-1.03,1.92,,65.73,BHH,-1.32167,0.0495842,0.00501194,1.00217 PSD95pdz3_Q384G,PSD95pdz3_384,PSD95pdz3,PSD95pdz3,P31016,1.00217,NO,384,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-1.699,-3.04,1.341,5.49339,,,,,23.54,,,,OPP,-1.41333,0.0758425,0.000216736,1.00217 Pab1_L191M,Pab1_191,Pab1,Pab1,P04147,1.00218,NO,191,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.2,-2.167,0.967,,0.204,E,B,,2.24,,,,HHP,-1.20133,0.175299,0.000583797,1.00218 beta-lactamase_2500_Q86R,beta-lactamase_2500_86,TEM-1,beta-lactamase_2500,P62593,1.00219,NO,86,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.4,-2.686,0.286,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.361275,0.00450027,1.00219 beta-lactamase_625_A148P,beta-lactamase_625_148,TEM-1,beta-lactamase_625,P62593,1.00219,NO,148,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.757,-3.925,2.168,,0.379,H,A,0.46,-0.55,1.359,,72.73,PHH,-1.40167,0.213352,0.00547053,1.00219 beta-lactamase_156_T112H,beta-lactamase_156_112,TEM-1,beta-lactamase_156,P62593,1.0022,NO,112,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.186,-4.734,2.548,,0.921,T,A,0.22,1.06,2.87,,73.78,HPA,-1.925,0.111618,0.00531334,1.0022 beta-lactamase_2500_Q37S,beta-lactamase_2500_37,TEM-1,beta-lactamase_2500,P62593,1.0022,NO,37,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.134,-2.839,0.705,,0.613,H,A,0.64,1.98,1.318,,73.08,APH,-2.06967,0.361275,0.00425833,1.0022 beta-lactamase_39_K144I,beta-lactamase_39_144,TEM-1,beta-lactamase_39,P62593,1.0022,NO,144,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-2.388,-4.014,1.626,,0.863,H,A,2.34,1.27,14.556,14.556,77.62,OBA,-1.904,0.0495842,0.00481141,1.0022 beta-lactamase_39_R91I,beta-lactamase_39_91,TEM-1,beta-lactamase_39,P62593,1.0022,NO,91,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.392,-4.049,2.657,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.0495842,0.00380226,1.0022 beta-lactamase_39_S51A,beta-lactamase_39_51,TEM-1,beta-lactamase_39,P62593,1.0022,NO,51,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.526,-2.32,0.794,,0.496,T,A,0.27,0.26,2.964,,72.73,PPO,-1.88467,0.0495842,0.00504821,1.0022 beta-lactamase_625_L120I,beta-lactamase_625_120,TEM-1,beta-lactamase_625,P62593,1.0022,NO,120,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.044,-2.541,1.497,,,H,A,0.55,-1.13,7.813,,64.69,AHO,-1.13633,0.213352,0.00143563,1.0022 beta-lactamase_625_N50T,beta-lactamase_625_50,TEM-1,beta-lactamase_625,P62593,1.0022,NO,50,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-2.979,-2.678,-0.301,,0.912,T,A,0.61,1.24,3.446,,77.62,HPP,-2.134,0.213352,0.0047211,1.0022 beta-lactamase_156_S96M,beta-lactamase_156_96,TEM-1,beta-lactamase_156,P62593,1.00221,NO,96,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.27,-3.49,1.22,,0.368,,b,0.27,0.39,2.838,,73.78,HPP,-2.019,0.111618,0.00551835,1.00221 beta-lactamase_2500_A211N,beta-lactamase_2500_211,TEM-1,beta-lactamase_2500,P62593,1.00221,NO,211,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.896,-2.729,0.833,,0.369,T,A,0.46,-0.69,2.061,,77.62,AHA,-1.94633,0.361275,0.00648183,1.00221 beta-lactamase_625_H24K,beta-lactamase_625_24,TEM-1,beta-lactamase_625,P62593,1.00221,NO,24,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-2.481,-3.455,0.974,,,,,,,2.708,,93.01,OBO,-2.0035,0.213352,0.00238894,1.00221 beta-lactamase_625_P217R,beta-lactamase_625_217,TEM-1,beta-lactamase_625,P62593,1.00221,NO,217,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-2.062,-3.069,1.007,,0.496,I,A,0.52,-0.33,1.087,,74.48,OOH,-1.64333,0.213352,0.00463211,1.00221 beta-lactamase_P105P,beta-lactamase_105,TEM-1,beta-lactamase,P62593,1.00221,NO,105,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.813,-0.813,,5.08236,0.226,T,A,0.98,0.8,1.154,,63.29,POH,-1.01533,0.221079,0.0011981,1.00221 beta-lactamase_156_G39D,beta-lactamase_156_39,TEM-1,beta-lactamase_156,P62593,1.00222,NO,39,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.864,-2.194,0.33,,0.701,T,L,0.29,0.47,1.454,,77.62,HOH,-1.53633,0.111618,0.00487611,1.00222 beta-lactamase_156_H110M,beta-lactamase_156_110,TEM-1,beta-lactamase_156,P62593,1.00222,NO,110,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-1.706,-3.324,1.618,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.111618,0.00441499,1.00222 beta-lactamase_156_R59G,beta-lactamase_156_59,TEM-1,beta-lactamase_156,P62593,1.00222,NO,59,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.345,-3.412,2.067,,0.329,S,L,1.2,-0.09,2.995,,73.08,HBO,-2.24267,0.111618,0.00318082,1.00222 beta-lactamase_156_E238W,beta-lactamase_156_238,TEM-1,beta-lactamase_156,P62593,1.00223,NO,238,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.111618,0.00743256,1.00223 beta-lactamase_39_N168G,beta-lactamase_39_168,TEM-1,beta-lactamase_39,P62593,1.00223,NO,168,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-1.029,-3.01,1.981,,0.113,G,A,0.61,-0.4,0.822,,44.41,HPA,-1.13233,0.0495842,0.00288667,1.00223 beta-lactamase_625_E102N,beta-lactamase_625_102,TEM-1,beta-lactamase_625,P62593,1.00223,NO,102,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.118,-3.596,1.478,,0.722,S,B,1.04,1.82,1.336,,73.08,HAH,-1.581,0.213352,0.00486633,1.00223 beta-lactamase_P12H,beta-lactamase_12,TEM-1,beta-lactamase,P62593,1.00223,NO,12,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-2.016,-4.601,2.585,,,,,,,2.88,,72.73,HOH,-2.05167,0.221079,0.00241653,1.00223 kka2_1:8_G74F,kka2_1:8_74,Kka2,kka2_1:8,P00552,1.00223,NO,74,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.18,-4.449,3.269,,0.621,T,l,0.29,0.2,2.014,,64.39,POH,-1.91667,0.100394,0.00587035,1.00223 kka2_1:8_G74F,kka2_1:8_74,Kka2,kka2_1:8,P00552,1.00223,NO,74,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.18,-4.449,3.269,,0.621,T,l,0.29,0.2,2.014,,64.39,POH,-1.91667,0.100394,0.00587035,1.00223 beta-lactamase_156_T187G,beta-lactamase_156_187,TEM-1,beta-lactamase_156,P62593,1.00224,NO,187,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.401,-3.394,1.993,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.111618,0.00491782,1.00224 beta-lactamase_156_T69C,beta-lactamase_156_69,TEM-1,beta-lactamase_156,P62593,1.00224,NO,69,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-0.973,-4.661,3.688,,,G,A,0.22,-1.24,4.194,,93.01,PPH,-1.01833,0.111618,0.00127498,1.00224 beta-lactamase_39_R41V,beta-lactamase_39_41,TEM-1,beta-lactamase_39,P62593,1.00224,NO,41,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-0.942,-3.751,2.809,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.0495842,0.00123327,1.00224 beta-lactamase_156_G253I,beta-lactamase_156_253,TEM-1,beta-lactamase_156,P62593,1.00225,NO,253,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.111618,0.00786358,1.00225 beta-lactamase_39_P255A,beta-lactamase_39_255,TEM-1,beta-lactamase_39,P62593,1.00225,NO,255,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.0495842,0.00499612,1.00225 beta-lactamase_0_L38G,beta-lactamase_0_38,TEM-1,beta-lactamase_0,P62593,1.00226,NO,38,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.343,-3.696,2.353,,0.088,H,A,0.55,0.2,13.556,13.556,64.34,PHO,-1.78033,0.0500837,0.00373244,1.00226 beta-lactamase_156_R92L,beta-lactamase_156_92,TEM-1,beta-lactamase_156,P62593,1.00226,NO,92,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.718,-2.788,1.07,,0.479,E,B,1.2,1.36,19.112,19.112,65.38,BBH,-1.50367,0.111618,0.00429626,1.00226 beta-lactamase_P181P,beta-lactamase_181,TEM-1,beta-lactamase,P62593,1.00226,NO,181,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.813,-0.813,,5.14752,,H,A,1.1,-1.14,1.357,,61.54,HOH,-1.795,0.221079,0.000703122,1.00226 beta-lactamase_39_G114P,beta-lactamase_39_114,TEM-1,beta-lactamase_39,P62593,1.00227,NO,114,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.094,-3.918,2.824,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.0495842,0.00224919,1.00227 beta-lactamase_39_T107G,beta-lactamase_39_107,TEM-1,beta-lactamase_39,P62593,1.00227,NO,107,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.117,-3.227,2.11,,,G,A,0.22,-0.06,2.686,,67.83,HPA,-1.265,0.0495842,0.00239347,1.00227 beta-lactamase_0_T186M,beta-lactamase_0_186,TEM-1,beta-lactamase_0,P62593,1.00229,NO,186,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.522,-3.419,0.897,,0.396,H,A,0.22,-0.28,16.606,16.606,77.62,HPP,-1.77633,0.0500837,0.00485034,1.00229 beta-lactamase_39_G142N,beta-lactamase_39_142,TEM-1,beta-lactamase_39,P62593,1.00229,NO,142,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.707,-3.445,2.738,,0.034,,p,0.29,-0.64,1.947,,64.69,OOO,-0.834,0.0495842,0.00060149,1.00229 beta-lactamase_625_T193M,beta-lactamase_625_193,TEM-1,beta-lactamase_625,P62593,1.00229,NO,193,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.914,-4.362,2.448,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.213352,0.00482669,1.00229 kka2_1:2_A71H,kka2_1:2_71,Kka2,kka2_1:2,P00552,1.00229,NO,71,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.824,-3.209,1.385,,0.553,H,A,0.46,0.08,9.788,,64.39,HHP,-1.74033,0.295029,0.00727707,1.00229 beta-lactamase_39_T187D,beta-lactamase_39_187,TEM-1,beta-lactamase_39,P62593,1.0023,NO,187,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.401,-2.769,1.368,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.0495842,0.00491782,1.0023 beta-lactamase_156_F70S,beta-lactamase_156_70,TEM-1,beta-lactamase_156,P62593,1.00231,NO,70,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.169,-2.713,1.544,,,H,A,0.58,-1.34,1.918,,63.99,PHB,-0.980667,0.111618,0.00193499,1.00231 beta-lactamase_2500_H151Y,beta-lactamase_2500_151,TEM-1,beta-lactamase_2500,P62593,1.00231,NO,151,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-2.96,-4.115,1.155,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.361275,0.00216946,1.00231 beta-lactamase_625_A282T,beta-lactamase_625_282,TEM-1,beta-lactamase_625,P62593,1.00231,NO,282,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.213352,0.0449821,1.00231 beta-lactamase_625_K286A,beta-lactamase_625_286,TEM-1,beta-lactamase_625,P62593,1.00231,NO,286,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.213352,,1.00231 beta-lactamase_625_M127F,beta-lactamase_625_127,TEM-1,beta-lactamase_625,P62593,1.00231,NO,127,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-2.251,-3.969,1.718,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.213352,0.00437927,1.00231 beta-lactamase_625_M66T,beta-lactamase_625_66,TEM-1,beta-lactamase_625,P62593,1.00231,NO,66,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.362,-3.498,2.136,,0.013,,A,0.55,-0.7,1.659,,73.08,OHH,-1.49567,0.213352,0.00412876,1.00231 beta-lactamase_625_T147I,beta-lactamase_625_147,TEM-1,beta-lactamase_625,P62593,1.00231,NO,147,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.149,-2.792,1.643,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.213352,0.00226017,1.00231 beta-lactamase_625_M180G,beta-lactamase_625_180,TEM-1,beta-lactamase_625,P62593,1.00232,NO,180,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-2.795,-3.389,0.594,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.213352,0.00552048,1.00232 beta-lactamase_625_R189Q,beta-lactamase_625_189,TEM-1,beta-lactamase_625,P62593,1.00232,NO,189,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.844,-2.262,0.418,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.213352,0.0050699,1.00232 beta-lactamase_625_T263Q,beta-lactamase_625_263,TEM-1,beta-lactamase_625,P62593,1.00232,NO,263,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.213352,0.0110582,1.00232 beta-lactamase_Q88N,beta-lactamase_88,TEM-1,beta-lactamase,P62593,1.00232,NO,88,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.086,-2.735,0.649,5.8056,0.807,,B,0.12,2.03,1.84,,77.62,APH,-1.53433,0.221079,0.00504167,1.00232 beta-lactamase_156_E238G,beta-lactamase_156_238,TEM-1,beta-lactamase_156,P62593,1.00233,NO,238,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.111618,0.00743256,1.00233 beta-lactamase_156_G39R,beta-lactamase_156_39,TEM-1,beta-lactamase_156,P62593,1.00233,NO,39,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.864,-3.077,1.213,,0.701,T,L,0.29,0.47,1.454,,77.62,HOH,-1.53633,0.111618,0.00487611,1.00233 beta-lactamase_39_S104T,beta-lactamase_39_104,TEM-1,beta-lactamase_39,P62593,1.00233,NO,104,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.015,-3.098,2.083,,0.04,,b,0.27,0.57,4.02,,63.29,HPO,-1.05267,0.0495842,0.00218083,1.00233 beta-lactamase_156_A34L,beta-lactamase_156_34,TEM-1,beta-lactamase_156,P62593,1.00234,NO,34,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.059,-2.191,0.132,,,H,A,0.46,-0.54,3.614,,73.78,AHA,-1.74967,0.111618,0.00407913,1.00234 beta-lactamase_39_N173V,beta-lactamase_39_173,TEM-1,beta-lactamase_39,P62593,1.00234,NO,173,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-2.663,-3.738,1.075,,1.044,T,l,0.61,1.25,1.426,,77.62,OPA,-1.46633,0.0495842,0.0033769,1.00234 beta-lactamase_39_R91M,beta-lactamase_39_91,TEM-1,beta-lactamase_39,P62593,1.00234,NO,91,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.392,-4.593,3.201,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.0495842,0.00380226,1.00234 beta-lactamase_39_V82N,beta-lactamase_39_82,TEM-1,beta-lactamase_39,P62593,1.00234,NO,82,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.325,-2.935,1.61,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.0495842,0.00397046,1.00234 beta-lactamase_0_G240T,beta-lactamase_0_240,TEM-1,beta-lactamase_0,P62593,1.00235,NO,240,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.0500837,0.00591201,1.00235 beta-lactamase_2500_I171S,beta-lactamase_2500_171,TEM-1,beta-lactamase_2500,P62593,1.00235,NO,171,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-2.431,-2.869,0.438,,0.361,,B,0.48,0.53,1.66,,77.62,HHO,-1.55533,0.361275,0.00623355,1.00235 beta-lactamase_156_Q86W,beta-lactamase_156_86,TEM-1,beta-lactamase_156,P62593,1.00236,NO,86,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.4,-5.489,3.089,,0.696,S,A,0.64,2.38,27.704,27.704,77.62,OPA,-1.61067,0.111618,0.00450027,1.00236 beta-lactamase_2500_E195P,beta-lactamase_2500_195,TEM-1,beta-lactamase_2500,P62593,1.00236,NO,195,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.186,-2.83,0.644,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.361275,0.00496565,1.00236 beta-lactamase_156_L191A,beta-lactamase_156_191,TEM-1,beta-lactamase_156,P62593,1.00237,NO,191,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.087,-2.236,1.149,,,H,A,0.55,0.09,1.372,,63.29,BHH,-1.445,0.111618,0.00263549,1.00237 beta-lactamase_2500_E238G,beta-lactamase_2500_238,TEM-1,beta-lactamase_2500,P62593,1.00237,NO,238,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.361275,0.00743256,1.00237 beta-lactamase_39_D48C,beta-lactamase_39_48,TEM-1,beta-lactamase_39,P62593,1.00237,NO,48,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.101,-5.125,4.024,,0.189,E,B,0.75,0.21,0.735,,50.35,HAH,-1.62467,0.0495842,0.0027273,1.00237 beta-lactamase_625_H94W,beta-lactamase_625_94,TEM-1,beta-lactamase_625,P62593,1.00237,NO,94,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-2.5,-5.512,3.012,,0.776,,B,0.17,1.24,19.42,19.42,77.62,HBH,-1.872,0.213352,0.00389226,1.00237 beta-lactamase_156_L89A,beta-lactamase_156_89,TEM-1,beta-lactamase_156,P62593,1.00238,NO,89,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.096,-2.465,1.369,,0.168,T,A,0.55,0.63,2.633,,64.34,PHO,-1.75767,0.111618,0.00207068,1.00238 beta-lactamase_156_P165C,beta-lactamase_156_165,TEM-1,beta-lactamase_156,P62593,1.00238,NO,165,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.373,-4.892,3.519,,0.203,T,A,0.52,-0.31,3.907,,73.78,AOA,-1.359,0.111618,0.00549538,1.00238 beta-lactamase_39_M270S,beta-lactamase_39_270,TEM-1,beta-lactamase_39,P62593,1.00238,NO,270,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.0495842,0.00767762,1.00238 beta-lactamase_625_A200H,beta-lactamase_625_200,TEM-1,beta-lactamase_625,P62593,1.00238,NO,200,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.878,-4.732,2.854,,0.757,H,A,0.46,-0.19,12.672,12.672,77.62,HHP,-2.001,0.213352,0.0060056,1.00238 beta-lactamase_Q88E,beta-lactamase_88,TEM-1,beta-lactamase,P62593,1.00238,NO,88,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.086,-2.76,0.674,5.8056,0.807,,B,0.12,2.03,1.84,,77.62,APH,-1.53433,0.221079,0.00504167,1.00238 Pab1_P135S,Pab1_135,Pab1,Pab1,P04147,1.00238,NO,135,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.457,-2.323,0.866,,,,,,,6.41,,81.8,BOA,-1.53367,0.175299,0.00148028,1.00238 beta-lactamase_2500_E61G,beta-lactamase_2500_61,TEM-1,beta-lactamase_2500,P62593,1.0024,NO,61,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.115,-2.393,0.278,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.361275,0.00440955,1.0024 beta-lactamase_625_E56L,beta-lactamase_625_56,TEM-1,beta-lactamase_625,P62593,1.0024,NO,56,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.043,-3.398,1.355,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.213352,0.00238534,1.0024 Pab1_I130L,Pab1_130,Pab1,Pab1,P04147,1.0024,NO,130,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.212,-2.275,1.063,,,E,B,1.23,0.01,,,,HHB,-1.188,0.175299,0.000351112,1.0024 beta-lactamase_625_P250M,beta-lactamase_625_250,TEM-1,beta-lactamase_625,P62593,1.00241,NO,250,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.213352,0.00550899,1.00241 beta-lactamase_2500_T112M,beta-lactamase_2500_112,TEM-1,beta-lactamase_2500,P62593,1.00243,NO,112,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.186,-4.812,2.626,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.361275,0.00531334,1.00243 beta-lactamase_39_A77M,beta-lactamase_39_77,TEM-1,beta-lactamase_39,P62593,1.00243,NO,77,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.234,-4.524,3.29,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.0495842,0.00282362,1.00243 beta-lactamase_625_I171Y,beta-lactamase_625_171,TEM-1,beta-lactamase_625,P62593,1.00243,NO,171,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-2.431,-4.204,1.773,,0.361,,B,0.48,0.53,3.869,,77.62,HHO,-1.55533,0.213352,0.00623355,1.00243 beta-lactamase_A211S,beta-lactamase_211,TEM-1,beta-lactamase,P62593,1.00243,NO,211,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.896,-2.788,0.892,5.54662,0.369,T,A,0.52,-0.69,2.061,,77.62,AHA,-1.94633,0.221079,0.00648183,1.00243 beta-lactamase_H156Q,beta-lactamase_156,TEM-1,beta-lactamase,P62593,1.00243,NO,156,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-3.156,-2.776,-0.38,6.00284,0.753,S,A,0.72,-0.6,6.456,6.456,77.62,ABH,-1.932,0.221079,0.00468596,1.00243 beta-lactamase_156_S51Y,beta-lactamase_156_51,TEM-1,beta-lactamase_156,P62593,1.00244,NO,51,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.526,-4.345,2.819,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.111618,0.00504821,1.00244 beta-lactamase_39_L284K,beta-lactamase_39_284,TEM-1,beta-lactamase_39,P62593,1.00244,NO,284,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.981,-3.504,1.523,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.0495842,0.0686156,1.00244 beta-lactamase_39_P25S,beta-lactamase_39_25,TEM-1,beta-lactamase_39,P62593,1.00244,NO,25,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.526,-3.274,1.748,,0.624,H,A,0.52,0.14,1.157,,73.08,BOA,-2.15367,0.0495842,0.00347571,1.00244 beta-lactamase_625_A282I,beta-lactamase_625_282,TEM-1,beta-lactamase_625,P62593,1.00244,NO,282,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.213352,0.0449821,1.00244 beta-lactamase_625_H24D,beta-lactamase_625_24,TEM-1,beta-lactamase_625,P62593,1.00244,NO,24,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-2.481,-2.42,-0.061,,,,,,,2.708,,93.01,OBO,-2.0035,0.213352,0.00238894,1.00244 beta-lactamase_625_T193G,beta-lactamase_625_193,TEM-1,beta-lactamase_625,P62593,1.00244,NO,193,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.914,-3.548,1.634,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.213352,0.00482669,1.00244 PSD95pdz3_Q374H,PSD95pdz3_374,PSD95pdz3,PSD95pdz3,P31016,1.00244,NO,374,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-1.699,-3.912,2.213,5.38825,,,,,17.3289,,,,APH,-1.47,0.0758425,0.000372298,1.00244 beta-lactamase_156_A222G,beta-lactamase_156_222,TEM-1,beta-lactamase_156,P62593,1.00245,NO,222,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.103,-1.732,-0.371,,0.233,H,A,0.46,-0.25,2.461,,77.62,PHH,-1.63733,0.111618,0.00466094,1.00245 beta-lactamase_625_D271L,beta-lactamase_625_271,TEM-1,beta-lactamase_625,P62593,1.00245,NO,271,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.213352,0.00752082,1.00245 beta-lactamase_625_H24V,beta-lactamase_625_24,TEM-1,beta-lactamase_625,P62593,1.00245,NO,24,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-2.481,-3.524,1.043,,,,,,,2.708,,93.01,OBO,-2.0035,0.213352,0.00238894,1.00245 Pab1_A178V,Pab1_178,Pab1,Pab1,P04147,1.00245,NO,178,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.579,-3.09,1.511,,0.019,H,A,0.64,0.64,2.7,,81.63,OHH,-1.61067,0.175299,0.00160192,1.00245 beta-lactamase_156_P250G,beta-lactamase_156_250,TEM-1,beta-lactamase_156,P62593,1.00246,NO,250,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.111618,0.00550899,1.00246 beta-lactamase_156_P65A,beta-lactamase_156_65,TEM-1,beta-lactamase_156,P62593,1.00246,NO,65,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.894,-3.096,2.202,,0.098,E,B,0.52,-0.62,0.623,,40.56,HOH,-1.03233,0.111618,0.00152776,1.00246 beta-lactamase_39_L218T,beta-lactamase_39_218,TEM-1,beta-lactamase_39,P62593,1.00246,NO,218,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.391,-2.536,1.145,,,I,b,0.55,-0.53,2.038,,74.48,OHH,-1.58867,0.0495842,0.00618274,1.00246 Pab1_D160G,Pab1_160,Pab1,Pab1,P04147,1.00246,NO,160,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.985,-2.95,1.965,,0.396,B,B,,1.12,,,,PAA,-1.30133,0.175299,0.000311977,1.00246 beta-lactamase_156_H94A,beta-lactamase_156_94,TEM-1,beta-lactamase_156,P62593,1.00247,NO,94,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-2.5,-2.468,-0.032,,0.776,,B,0.17,1.24,11.583,11.583,77.62,HBH,-1.872,0.111618,0.00389226,1.00247 beta-lactamase_2500_V29S,beta-lactamase_2500_29,TEM-1,beta-lactamase_2500,P62593,1.00248,NO,29,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-2.856,-2.693,-0.163,,0.733,H,A,0.44,-0.78,1.931,,93.01,HHB,-2.24733,0.361275,0.00318969,1.00248 beta-lactamase_39_A182D,beta-lactamase_39_182,TEM-1,beta-lactamase_39,P62593,1.00248,NO,182,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.777,-2.705,0.928,,0.136,H,A,0.46,-0.66,2.598,,93.01,OHH,-1.27367,0.0495842,0.00559099,1.00248 beta-lactamase_39_T131A,beta-lactamase_39_131,TEM-1,beta-lactamase_39,P62593,1.00248,NO,131,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.328,-2.085,0.757,,,H,A,0.22,-0.69,3.306,,67.48,PPH,-1.00867,0.0495842,0.00345886,1.00248 beta-lactamase_625_K30S,beta-lactamase_625_30,TEM-1,beta-lactamase_625,P62593,1.00248,NO,30,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-2.307,-3.277,0.97,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.213352,0.00448593,1.00248 beta-lactamase_625_R91S,beta-lactamase_625_91,TEM-1,beta-lactamase_625,P62593,1.00248,NO,91,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.392,-3.342,1.95,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.213352,0.00380226,1.00248 beta-lactamase_625_R92W,beta-lactamase_625_92,TEM-1,beta-lactamase_625,P62593,1.00248,NO,92,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.718,-5.477,3.759,,0.479,E,B,1.2,1.36,3.069,,65.38,BBH,-1.50367,0.213352,0.00429626,1.00248 Pab1_I183V,Pab1_183,Pab1,Pab1,P04147,1.00248,NO,183,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.302,-1.793,0.491,,0.308,T,B,1,1.08,1.29,,75.56,HHA,-1.27167,0.175299,0.000574345,1.00248 beta-lactamase_156_T264S,beta-lactamase_156_264,TEM-1,beta-lactamase_156,P62593,1.00249,NO,264,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.985,-1.764,-0.221,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.111618,0.0119399,1.00249 beta-lactamase_39_R275A,beta-lactamase_39_275,TEM-1,beta-lactamase_39,P62593,1.00249,NO,275,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.0495842,0.0141984,1.00249 beta-lactamase_A225I,beta-lactamase_225,TEM-1,beta-lactamase,P62593,1.00249,NO,225,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.845,-4.041,2.196,6.5181,1,T,B,0.58,-0.38,4.077,,74.48,OHO,-1.39967,0.221079,0.00465057,1.00249 beta-lactamase_L196M,beta-lactamase_196,TEM-1,beta-lactamase,P62593,1.00249,NO,196,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-2.478,-3.442,0.964,,0.518,S,A,0.55,1.35,,,77.62,AHH,-1.839,0.221079,0.00512144,1.00249 kka2_1:8_M1R,kka2_1:8_1,Kka2,kka2_1:8,P00552,1.00249,NO,1,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.787,-3.648,1.861,,,,,,,16.725,16.725,62.12,NAHH,-1.787,0.100394,0.00251939,1.00249 kka2_1:8_M1R,kka2_1:8_1,Kka2,kka2_1:8,P00552,1.00249,NO,1,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.787,-3.648,1.861,,,,,,,16.725,16.725,62.12,NAHH,-1.787,0.100394,0.00251939,1.00249 beta-lactamase_156_E272L,beta-lactamase_156_272,TEM-1,beta-lactamase_156,P62593,1.00251,NO,272,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.111618,0.00545371,1.00251 beta-lactamase_156_G253R,beta-lactamase_156_253,TEM-1,beta-lactamase_156,P62593,1.00251,NO,253,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.111618,0.00786358,1.00251 beta-lactamase_156_K213I,beta-lactamase_156_213,TEM-1,beta-lactamase_156,P62593,1.00251,NO,213,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.81,-4.142,2.332,,0.67,,A,2.34,0.29,3.924,,67.83,ABH,-1.57767,0.111618,0.00610411,1.00251 beta-lactamase_2500_Q37A,beta-lactamase_2500_37,TEM-1,beta-lactamase_2500,P62593,1.00251,NO,37,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.134,-2.542,0.408,,0.613,H,A,0.64,1.98,1.318,,73.08,APH,-2.06967,0.361275,0.00425833,1.00251 beta-lactamase_156_C75A,beta-lactamase_156_75,TEM-1,beta-lactamase_156,P62593,1.00252,NO,75,C,A,CA,Special,Hydrophobic,5.07,6,0.93,195,121,89,-32,108.5,88.6,-19.9,-1.245,-1.87,0.625,,,H,A,0.46,-0.87,0.876,,50,HOO,-1.24333,0.111618,0.0034616,1.00252 beta-lactamase_625_Q37H,beta-lactamase_625_37,TEM-1,beta-lactamase_625,P62593,1.00252,NO,37,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.134,-3.314,1.18,,0.613,H,A,0.64,1.98,1.318,,73.08,APH,-2.06967,0.213352,0.00425833,1.00252 beta-lactamase_0_A124T,beta-lactamase_0_124,TEM-1,beta-lactamase_0,P62593,1.00253,NO,124,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.181,-1.586,0.405,,,H,A,0.46,-0.9,1.876,,64.34,HHH,-1.152,0.0500837,0.00481399,1.00253 beta-lactamase_156_L74T,beta-lactamase_156_74,TEM-1,beta-lactamase_156,P62593,1.00253,NO,74,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.296,-3.432,2.136,,,H,A,0.55,-0.91,0.746,,50,HHO,-1.34933,0.111618,0.00493255,1.00253 beta-lactamase_156_R91A,beta-lactamase_156_91,TEM-1,beta-lactamase_156,P62593,1.00253,NO,91,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.392,-2.55,1.158,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.111618,0.00380226,1.00253 beta-lactamase_39_A185T,beta-lactamase_39_185,TEM-1,beta-lactamase_39,P62593,1.00253,NO,185,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.406,-2.128,0.722,,,H,A,0.46,-1.02,2.68,,65.03,HHP,-1.84033,0.0495842,0.00467449,1.00253 beta-lactamase_39_R59C,beta-lactamase_39_59,TEM-1,beta-lactamase_39,P62593,1.00253,NO,59,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.345,-2.854,1.509,,0.329,S,L,1.2,-0.09,1.806,,73.08,HBO,-2.24267,0.0495842,0.00318082,1.00253 beta-lactamase_2500_A182Q,beta-lactamase_2500_182,TEM-1,beta-lactamase_2500,P62593,1.00254,NO,182,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.777,-3.097,1.32,,0.136,H,A,0.46,-0.66,2.032,,93.01,OHH,-1.27367,0.361275,0.00559099,1.00254 beta-lactamase_2500_S221K,beta-lactamase_2500_221,TEM-1,beta-lactamase_2500,P62593,1.00254,NO,221,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.754,-2.447,0.693,,0.624,H,A,0.27,-0.2,1.971,,74.48,BPH,-1.59967,0.361275,0.0046094,1.00254 beta-lactamase_625_Q97W,beta-lactamase_625_97,TEM-1,beta-lactamase_625,P62593,1.00254,NO,97,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.072,-5.457,3.385,,0.823,G,A,0.64,2.42,16.954,16.954,77.62,PPP,-2.43833,0.213352,0.0045116,1.00254 beta-lactamase_156_F58A,beta-lactamase_156_58,TEM-1,beta-lactamase_156,P62593,1.00255,NO,58,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-2.914,-3.389,0.475,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.111618,0.00523369,1.00255 beta-lactamase_625_T126A,beta-lactamase_625_126,TEM-1,beta-lactamase_625,P62593,1.00255,NO,126,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.122,-2.955,1.833,,0.05,H,A,0.22,-0.05,0.817,,44.41,HPH,-1.60467,0.213352,0.00244552,1.00255 gb1_D248P,gb1_248,gb1,gb1,P06654,1.00255,NO,248,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.569,-3.466,1.897,,,,,,,0.344,,11.83,HAH,-1.673,0.177985,0.001865,1.00255 Pab1_N132K,Pab1_132,Pab1,Pab1,P04147,1.00255,NO,132,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-1.079,-3.049,1.97,,0.412,S,l,,0.9,,,,BPH,-1.067,0.175299,0.000347671,1.00255 beta-lactamase_0_T264E,beta-lactamase_0_264,TEM-1,beta-lactamase_0,P62593,1.00256,NO,264,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.0500837,0.0119399,1.00256 beta-lactamase_39_L55G,beta-lactamase_39_55,TEM-1,beta-lactamase_39,P62593,1.00256,NO,55,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.86,-3.665,1.805,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.0495842,0.00403741,1.00256 beta-lactamase_625_A268F,beta-lactamase_625_268,TEM-1,beta-lactamase_625,P62593,1.00256,NO,268,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.213352,0.0102525,1.00256 kka2_1:2_R44G,kka2_1:2_44,Kka2,kka2_1:2,P00552,1.00256,NO,44,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.062,-2.106,0.044,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.295029,0.00745043,1.00256 beta-lactamase_156_A282C,beta-lactamase_156_282,TEM-1,beta-lactamase_156,P62593,1.00257,NO,282,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.111618,0.0449821,1.00257 beta-lactamase_156_D99M,beta-lactamase_156_99,TEM-1,beta-lactamase_156,P62593,1.00257,NO,99,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.191,-3.198,2.007,,0.402,G,A,0.75,0.36,3.529,,64.69,PAH,-1.794,0.111618,0.00305446,1.00257 beta-lactamase_P12F,beta-lactamase_12,TEM-1,beta-lactamase,P62593,1.00257,NO,12,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-2.016,-2.795,0.779,,,,,,,2.88,,72.73,HOH,-2.05167,0.221079,0.00241653,1.00257 beta-lactamase_Q86T,beta-lactamase_86,TEM-1,beta-lactamase,P62593,1.00257,NO,86,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.4,-2.587,0.187,5.39897,0.696,S,A,0.12,2.38,2.105,,77.62,OPA,-1.61067,0.221079,0.00450027,1.00257 kka2_1:8_S105L,kka2_1:8_105,Kka2,kka2_1:8,P00552,1.00257,NO,105,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.945,-2.961,1.016,,0.056,S,B,0.27,-1.04,2.115,,65.53,PPB,-2.17033,0.100394,0.00847233,1.00257 kka2_1:8_S105L,kka2_1:8_105,Kka2,kka2_1:8,P00552,1.00257,NO,105,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.945,-2.961,1.016,,0.056,S,B,0.27,-1.04,2.115,,65.53,PPB,-2.17033,0.100394,0.00847233,1.00257 beta-lactamase_156_D271P,beta-lactamase_156_271,TEM-1,beta-lactamase_156,P62593,1.00258,NO,271,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.111618,0.00752082,1.00258 beta-lactamase_2500_S80A,beta-lactamase_2500_80,TEM-1,beta-lactamase_2500,P62593,1.00258,NO,80,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.029,-1.631,-0.398,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.361275,0.00565569,1.00258 beta-lactamase_2500_V260C,beta-lactamase_2500_260,TEM-1,beta-lactamase_2500,P62593,1.00258,NO,260,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.361275,0.00471757,1.00258 beta-lactamase_625_T193C,beta-lactamase_625_193,TEM-1,beta-lactamase_625,P62593,1.00258,NO,193,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.914,-4.857,2.943,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.213352,0.00482669,1.00258 beta-lactamase_0_T178I,beta-lactamase_0_178,TEM-1,beta-lactamase_0,P62593,1.00259,NO,178,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-0.791,-3.56,2.769,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.0500837,0.000684366,1.00259 beta-lactamase_156_M184A,beta-lactamase_156_184,TEM-1,beta-lactamase_156,P62593,1.00259,NO,184,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.593,-2.223,0.63,,,H,A,0.55,-0.87,1.671,,62.94,HHH,-1.41,0.111618,0.00356019,1.00259 beta-lactamase_39_A182R,beta-lactamase_39_182,TEM-1,beta-lactamase_39,P62593,1.00259,NO,182,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.777,-2.31,0.533,,0.136,H,A,0.46,-0.66,2.598,,93.01,OHH,-1.27367,0.0495842,0.00559099,1.00259 beta-lactamase_39_G240R,beta-lactamase_39_240,TEM-1,beta-lactamase_39,P62593,1.00259,NO,240,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.0495842,0.00591201,1.00259 beta-lactamase_39_Q37W,beta-lactamase_39_37,TEM-1,beta-lactamase_39,P62593,1.00259,NO,37,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.134,-3.439,1.305,,0.613,H,A,0.64,1.98,22.282,22.282,73.08,APH,-2.06967,0.0495842,0.00425833,1.00259 beta-lactamase_156_M115Y,beta-lactamase_156_115,TEM-1,beta-lactamase_156,P62593,1.0026,NO,115,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.389,-3.961,2.572,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.111618,0.0034337,1.0026 beta-lactamase_156_Q97D,beta-lactamase_156_97,TEM-1,beta-lactamase_156,P62593,1.0026,NO,97,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.072,-3.567,1.495,,0.823,G,A,0.64,2.42,4.457,,77.62,PPP,-2.43833,0.111618,0.0045116,1.0026 beta-lactamase_2500_L49M,beta-lactamase_2500_49,TEM-1,beta-lactamase_2500,P62593,1.0026,NO,49,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.897,-4.411,2.514,,0.131,T,A,0.55,0.04,6.681,,64.69,AHP,-1.99233,0.361275,0.00401477,1.0026 beta-lactamase_39_G240A,beta-lactamase_39_240,TEM-1,beta-lactamase_39,P62593,1.0026,NO,240,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.0495842,0.00591201,1.0026 beta-lactamase_625_I54S,beta-lactamase_625_54,TEM-1,beta-lactamase_625,P62593,1.0026,NO,54,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-2.838,-3.459,0.621,,0.669,E,B,0.48,-0.14,3.946,,73.78,BHH,-2.337,0.213352,0.00403589,1.0026 kka2_1:8_M148V,kka2_1:8_148,Kka2,kka2_1:8,P00552,1.0026,NO,148,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.847,-1.708,-0.139,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.100394,0.00982664,1.0026 kka2_1:8_M148V,kka2_1:8_148,Kka2,kka2_1:8,P00552,1.0026,NO,148,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.847,-1.708,-0.139,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.100394,0.00982664,1.0026 beta-lactamase_156_E175M,beta-lactamase_156_175,TEM-1,beta-lactamase_156,P62593,1.00261,NO,175,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.336,-3.397,1.061,,0.551,,A,1.04,1.05,2.334,,77.62,AAB,-1.31233,0.111618,0.00482205,1.00261 beta-lactamase_156_P25M,beta-lactamase_156_25,TEM-1,beta-lactamase_156,P62593,1.00261,NO,25,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.526,-4.708,3.182,,0.624,H,A,0.52,0.14,1.079,,73.08,BOA,-2.15367,0.111618,0.00347571,1.00261 beta-lactamase_156_Q88K,beta-lactamase_156_88,TEM-1,beta-lactamase_156,P62593,1.00261,NO,88,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.086,-2.839,0.753,,0.807,,B,0.64,2.03,0.911,,77.62,APH,-1.53433,0.111618,0.00504167,1.00261 beta-lactamase_156_V259L,beta-lactamase_156_259,TEM-1,beta-lactamase_156,P62593,1.00261,NO,259,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.111618,0.0070773,1.00261 beta-lactamase_156_W208E,beta-lactamase_156_208,TEM-1,beta-lactamase_156,P62593,1.00261,NO,208,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-0.818,-3.89,3.072,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.111618,0.00126609,1.00261 beta-lactamase_39_A278H,beta-lactamase_39_278,TEM-1,beta-lactamase_39,P62593,1.00261,NO,278,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.0495842,0.0310297,1.00261 beta-lactamase_39_L167N,beta-lactamase_39_167,TEM-1,beta-lactamase_39,P62593,1.00261,NO,167,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.138,-4.008,2.87,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.0495842,0.00303566,1.00261 beta-lactamase_0_R92I,beta-lactamase_0_92,TEM-1,beta-lactamase_0,P62593,1.00262,NO,92,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.718,-3.773,2.055,,0.479,E,B,1.2,1.36,2.331,,65.38,BBH,-1.50367,0.0500837,0.00429626,1.00262 beta-lactamase_156_A247V,beta-lactamase_156_247,TEM-1,beta-lactamase_156,P62593,1.00262,NO,247,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.111618,0.00611275,1.00262 beta-lactamase_2500_G253M,beta-lactamase_2500_253,TEM-1,beta-lactamase_2500,P62593,1.00262,NO,253,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.361275,0.00786358,1.00262 beta-lactamase_39_Q276L,beta-lactamase_39_276,TEM-1,beta-lactamase_39,P62593,1.00262,NO,276,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.0495842,0.0191712,1.00262 beta-lactamase_39_R257T,beta-lactamase_39_257,TEM-1,beta-lactamase_39,P62593,1.00262,NO,257,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.0495842,0.00756629,1.00262 beta-lactamase_39_A40G,beta-lactamase_39_40,TEM-1,beta-lactamase_39,P62593,1.00263,NO,40,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.402,-1.32,-0.082,,0.155,S,B,0.46,0.21,0.783,,73.78,OHB,-1.40267,0.0495842,0.00490026,1.00263 beta-lactamase_625_K286E,beta-lactamase_625_286,TEM-1,beta-lactamase_625,P62593,1.00263,NO,286,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.213352,,1.00263 beta-lactamase_625_P60G,beta-lactamase_625_60,TEM-1,beta-lactamase_625,P62593,1.00263,NO,60,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-2.469,-2.095,-0.374,,0.256,T,A,0.52,-0.56,3.653,,77.62,BOA,-1.97633,0.213352,0.00521318,1.00263 beta-lactamase_0_L74V,beta-lactamase_0_74,TEM-1,beta-lactamase_0,P62593,1.00264,NO,74,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.296,-2.972,1.676,,,H,A,0.55,-0.91,1.46,,50,HHO,-1.34933,0.0500837,0.00493255,1.00264 beta-lactamase_2500_R202T,beta-lactamase_2500_202,TEM-1,beta-lactamase_2500,P62593,1.00264,NO,202,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.292,-3.438,2.146,,0.188,H,A,1.2,0.62,3.734,,77.62,PBP,-1.54767,0.361275,0.00321899,1.00264 beta-lactamase_A170G,beta-lactamase_170,TEM-1,beta-lactamase,P62593,1.00264,NO,170,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.237,-1.884,0.647,5.19261,0.126,,L,2.34,-0.35,2.427,,64.69,AHH,-1.63267,0.221079,0.00431903,1.00264 Pab1_V171V,Pab1_171,Pab1,Pab1,P04147,1.00264,NO,171,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.113,-1.113,,,0.008,E,b,0.23,-0.34,,,,HHB,-1.19733,0.175299,0.000298662,1.00264 beta-lactamase_156_M184F,beta-lactamase_156_184,TEM-1,beta-lactamase_156,P62593,1.00265,NO,184,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.593,-2.94,1.347,,,H,A,0.55,-0.87,1.671,,62.94,HHH,-1.41,0.111618,0.00356019,1.00265 beta-lactamase_156_R239G,beta-lactamase_156_239,TEM-1,beta-lactamase_156,P62593,1.00265,NO,239,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-0.819,-3.876,3.057,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.111618,0.00213852,1.00265 beta-lactamase_625_A282L,beta-lactamase_625_282,TEM-1,beta-lactamase_625,P62593,1.00265,NO,282,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.586,-3.183,1.597,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.213352,0.0449821,1.00265 beta-lactamase_V42L,beta-lactamase_42,TEM-1,beta-lactamase,P62593,1.00265,NO,42,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.564,-1.709,0.145,5.27904,0.017,E,B,1.64,-0.51,2.024,,63.99,BHO,-1.042,0.221079,0.00404515,1.00265 E1_Ubiquitin_H70I,E1_Ubiquitin_70,Uba1,E1_Ubiquitin,P0CG63,1.00265,NO,70,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-1.36,,,,0.05,E,B,0.61,-0.97,,,93.18,HBH,-1.146,0.18783,0.00206914,1.00265 E1_Ubiquitin_I44L,E1_Ubiquitin_44,Uba1,E1_Ubiquitin,P0CG63,1.00265,NO,44,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.432,-2.56,1.128,,,E,B,0.27,-1.17,4.57,,78.74,HHH,-1.25633,0.18783,0.00209731,1.00265 E1_Ubiquitin_L71S,E1_Ubiquitin_71,Uba1,E1_Ubiquitin,P0CG63,1.00265,NO,71,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.039,-3.428,2.389,,0.591,E,B,,-0.69,,,,BHB,-1.19433,0.18783,0.00148349,1.00265 E1_Ubiquitin_R42Y,E1_Ubiquitin_42,Uba1,E1_Ubiquitin,P0CG63,1.00265,NO,42,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.302,-4.033,2.731,,0.244,E,B,,-0.54,,,,PBH,-1.24667,0.18783,0.00224033,1.00265 Pab1_D160A,Pab1_160,Pab1,Pab1,P04147,1.00265,NO,160,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.985,-3.12,2.135,,0.396,B,B,,1.12,,,,PAA,-1.30133,0.175299,0.000311977,1.00265 beta-lactamase_39_F228W,beta-lactamase_39_228,TEM-1,beta-lactamase_39,P62593,1.00266,NO,228,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-2.342,-5.275,2.933,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.0495842,0.0046669,1.00266 beta-lactamase_39_L150V,beta-lactamase_39_150,TEM-1,beta-lactamase_39,P62593,1.00266,NO,150,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.326,-2.348,1.022,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.0495842,0.00463171,1.00266 beta-lactamase_Q88S,beta-lactamase_88,TEM-1,beta-lactamase,P62593,1.00266,NO,88,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.086,-2.48,0.394,5.8056,0.807,,B,0.12,2.03,1.84,,77.62,APH,-1.53433,0.221079,0.00504167,1.00266 beta-lactamase_156_A77W,beta-lactamase_156_77,TEM-1,beta-lactamase_156,P62593,1.00267,NO,77,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.234,-5.367,4.133,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.111618,0.00282362,1.00267 beta-lactamase_156_T198C,beta-lactamase_156_198,TEM-1,beta-lactamase_156,P62593,1.00267,NO,198,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.168,-4.902,2.734,,0.489,,B,0.22,-0.13,10.771,10.771,73.78,HPH,-1.98767,0.111618,0.004311,1.00267 beta-lactamase_156_A282R,beta-lactamase_156_282,TEM-1,beta-lactamase_156,P62593,1.00268,NO,282,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.111618,0.0449821,1.00268 beta-lactamase_156_K213H,beta-lactamase_156_213,TEM-1,beta-lactamase_156,P62593,1.00268,NO,213,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.81,-4.552,2.742,,0.67,,A,2.34,0.29,3.924,,67.83,ABH,-1.57767,0.111618,0.00610411,1.00268 beta-lactamase_2500_Q267L,beta-lactamase_2500_267,TEM-1,beta-lactamase_2500,P62593,1.00268,NO,267,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.361275,0.0102128,1.00268 beta-lactamase_39_Q204L,beta-lactamase_39_204,TEM-1,beta-lactamase_39,P62593,1.00268,NO,204,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-1.382,-2.716,1.334,,0.204,H,A,0.64,0.09,0.489,,66.08,PPH,-1.49067,0.0495842,0.00364106,1.00268 beta-lactamase_625_K109G,beta-lactamase_625_109,TEM-1,beta-lactamase_625,P62593,1.00268,NO,109,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.734,-2.852,1.118,,0.787,G,A,2.34,2.21,7.243,,72.73,ABB,-1.63333,0.213352,0.00462493,1.00268 beta-lactamase_K252R,beta-lactamase_252,TEM-1,beta-lactamase,P62593,1.00268,NO,252,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.94,-1.945,0.005,5.56823,0.766,,B,1.82,1.16,21.796,21.796,67.83,OBO,-2.03333,0.221079,0.00575769,1.00268 beta-lactamase_2500_I93L,beta-lactamase_2500_93,TEM-1,beta-lactamase_2500,P62593,1.00269,NO,93,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.401,-2.05,0.649,,0.128,E,B,0.48,0.44,19.374,19.374,67.83,BHB,-1.873,0.361275,0.00527066,1.00269 beta-lactamase_625_L167I,beta-lactamase_625_167,TEM-1,beta-lactamase_625,P62593,1.00269,NO,167,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.138,-3.085,1.947,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.213352,0.00303566,1.00269 beta-lactamase_625_R63T,beta-lactamase_625_63,TEM-1,beta-lactamase_625,P62593,1.0027,NO,63,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-0.943,-3.447,2.504,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.213352,0.00126938,1.0027 PSD95pdz3_K393R,PSD95pdz3_393,PSD95pdz3,PSD95pdz3,P31016,1.0027,NO,393,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.416,-2.715,1.299,5.42682,,,,,22.0122,,,,HBO,-1.4265,0.0758425,0.000879298,1.0027 beta-lactamase_156_A182F,beta-lactamase_156_182,TEM-1,beta-lactamase_156,P62593,1.00271,NO,182,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.777,-4.357,2.58,,0.136,H,A,0.46,-0.66,16.784,16.784,93.01,OHH,-1.27367,0.111618,0.00559099,1.00271 beta-lactamase_156_D174T,beta-lactamase_156_174,TEM-1,beta-lactamase_156,P62593,1.00271,NO,174,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.738,-3.421,2.683,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.111618,0.00125633,1.00271 beta-lactamase_156_N98H,beta-lactamase_156_98,TEM-1,beta-lactamase_156,P62593,1.00271,NO,98,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-2.973,-3.344,0.371,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.111618,0.00505389,1.00271 beta-lactamase_2500_T138E,beta-lactamase_2500_138,TEM-1,beta-lactamase_2500,P62593,1.00271,NO,138,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.506,-2.168,-0.338,,0.662,H,A,0.22,-0.03,30.445,30.445,73.78,HPP,-1.81233,0.361275,0.00487868,1.00271 beta-lactamase_625_A183P,beta-lactamase_625_183,TEM-1,beta-lactamase_625,P62593,1.00271,NO,183,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.231,-3.812,2.581,,0.155,H,A,0.46,-0.91,23.859,23.859,77.62,HHH,-1.53367,0.213352,0.00296631,1.00271 beta-lactamase_625_E119H,beta-lactamase_625_119,TEM-1,beta-lactamase_625,P62593,1.00271,NO,119,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.412,-4.521,3.109,,0.358,H,A,1.04,0.51,1.034,,63.99,BAH,-1.623,0.213352,0.00386966,1.00271 beta-lactamase_625_V101T,beta-lactamase_625_101,TEM-1,beta-lactamase_625,P62593,1.00271,NO,101,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.295,-3.446,2.151,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.213352,0.00374492,1.00271 kka2_1:1_A79K,kka2_1:1_79,Kka2,kka2_1:1,P00552,1.00271,NO,79,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.368,-2.882,0.514,,0.563,.,B,0.46,-0.43,7.792,7.792,71.59,HHH,-1.752,0.520039,0.00664821,1.00271 beta-lactamase_156_Q267Y,beta-lactamase_156_267,TEM-1,beta-lactamase_156,P62593,1.00272,NO,267,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.111618,0.0102128,1.00272 beta-lactamase_156_S233G,beta-lactamase_156_233,TEM-1,beta-lactamase_156,P62593,1.00272,NO,233,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.886,-3.274,1.388,,0.016,E,B,0.27,-1.01,4.111,,77.62,BPO,-1.17267,0.111618,0.00311415,1.00272 beta-lactamase_156_S80W,beta-lactamase_156_80,TEM-1,beta-lactamase_156,P62593,1.00272,NO,80,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.029,-5.529,3.5,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.111618,0.00565569,1.00272 beta-lactamase_156_V214A,beta-lactamase_156_214,TEM-1,beta-lactamase_156,P62593,1.00272,NO,214,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.299,-2.434,1.135,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.111618,0.00628442,1.00272 beta-lactamase_625_A182H,beta-lactamase_625_182,TEM-1,beta-lactamase_625,P62593,1.00272,NO,182,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.777,-3.358,1.581,,0.136,H,A,0.46,-0.66,16.784,16.784,93.01,OHH,-1.27367,0.213352,0.00559099,1.00272 beta-lactamase_156_S80Y,beta-lactamase_156_80,TEM-1,beta-lactamase_156,P62593,1.00273,NO,80,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.029,-4.297,2.268,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.111618,0.00565569,1.00273 beta-lactamase_39_A211R,beta-lactamase_39_211,TEM-1,beta-lactamase_39,P62593,1.00273,NO,211,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.896,-3.077,1.181,,0.369,T,A,0.46,-0.69,1.419,,77.62,AHA,-1.94633,0.0495842,0.00648183,1.00273 beta-lactamase_L188F,beta-lactamase_188,TEM-1,beta-lactamase,P62593,1.00273,NO,188,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.166,-3.771,2.605,5.55434,,H,A,1.07,-0.3,1.574,,60.14,PHB,-1.47033,0.221079,0.00295687,1.00273 beta-lactamase_Q86L,beta-lactamase_86,TEM-1,beta-lactamase,P62593,1.00273,NO,86,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.4,-2.558,0.158,5.39897,0.696,S,A,0.12,2.38,2.105,,77.62,OPA,-1.61067,0.221079,0.00450027,1.00273 Pab1_P200I,Pab1_200,Pab1,Pab1,P04147,1.00273,NO,200,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.871,-3.665,1.794,,,,,,,3.877,,80.59,HOO,-1.7005,0.175299,0.00190795,1.00273 beta-lactamase_0_T158R,beta-lactamase_0_158,TEM-1,beta-lactamase_0,P62593,1.00274,NO,158,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.116,-3.803,2.687,,0.036,,B,0.22,-0.85,1.041,,69.58,HPB,-1.269,0.0500837,0.00341825,1.00274 beta-lactamase_156_R239C,beta-lactamase_156_239,TEM-1,beta-lactamase_156,P62593,1.00274,NO,239,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.111618,0.00213852,1.00274 beta-lactamase_2500_D36S,beta-lactamase_2500_36,TEM-1,beta-lactamase_2500,P62593,1.00274,NO,36,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.732,-2.107,-0.625,,0.555,H,A,0.75,1.17,2.26,,77.62,AAP,-1.91167,0.361275,0.00476483,1.00274 beta-lactamase_2500_S221T,beta-lactamase_2500_221,TEM-1,beta-lactamase_2500,P62593,1.00274,NO,221,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.754,-3.292,1.538,,0.624,H,A,0.27,-0.2,1.971,,74.48,BPH,-1.59967,0.361275,0.0046094,1.00274 beta-lactamase_39_L28P,beta-lactamase_39_28,TEM-1,beta-lactamase_39,P62593,1.00274,NO,28,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.579,-4.027,2.448,,0.277,H,A,0.55,-0.16,3.262,,93.01,PHH,-2.11333,0.0495842,0.00359321,1.00274 beta-lactamase_156_K144Q,beta-lactamase_156_144,TEM-1,beta-lactamase_156,P62593,1.00275,NO,144,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-2.388,-2.378,-0.01,,0.863,H,A,2.34,1.27,2.073,,77.62,OBA,-1.904,0.111618,0.00481141,1.00275 beta-lactamase_156_L197A,beta-lactamase_156_197,TEM-1,beta-lactamase_156,P62593,1.00275,NO,197,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.853,-2.357,1.504,,0.007,S,B,0.55,0.33,1.58,,60.14,HHP,-1.833,0.111618,0.00144602,1.00275 beta-lactamase_625_H151R,beta-lactamase_625_151,TEM-1,beta-lactamase_625,P62593,1.00275,NO,151,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-2.96,-1.217,-1.743,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.213352,0.00216946,1.00275 kka2_1:4_W236F,kka2_1:4_236,Kka2,kka2_1:4,P00552,1.00275,NO,236,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-1.363,-2.652,1.289,,0.303,H,A,0.47,-0.76,2.277,,48.48,AHH,-1.81267,0.168804,0.0088796,1.00275 beta-lactamase_156_H110P,beta-lactamase_156_110,TEM-1,beta-lactamase_156,P62593,1.00276,NO,110,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-1.706,-2.996,1.29,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.111618,0.00441499,1.00276 beta-lactamase_625_P60A,beta-lactamase_625_60,TEM-1,beta-lactamase_625,P62593,1.00276,NO,60,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-2.469,-1.436,-1.033,,0.256,T,A,0.52,-0.56,3.653,,77.62,BOA,-1.97633,0.213352,0.00521318,1.00276 beta-lactamase_156_E279A,beta-lactamase_156_279,TEM-1,beta-lactamase_156,P62593,1.00277,NO,279,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.111618,0.0192826,1.00277 beta-lactamase_156_R275F,beta-lactamase_156_275,TEM-1,beta-lactamase_156,P62593,1.00277,NO,275,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.111618,0.0141984,1.00277 beta-lactamase_625_E238I,beta-lactamase_625_238,TEM-1,beta-lactamase_625,P62593,1.00277,NO,238,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.213352,0.00743256,1.00277 beta-lactamase_625_G76S,beta-lactamase_625_76,TEM-1,beta-lactamase_625,P62593,1.00277,NO,76,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.189,-2.528,1.339,,,H,A,0.29,-0.67,3.059,,67.83,OOH,-1.22267,0.213352,0.00476637,1.00277 beta-lactamase_625_H24N,beta-lactamase_625_24,TEM-1,beta-lactamase_625,P62593,1.00277,NO,24,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-2.481,-3.496,1.015,,,,,,,2.708,,93.01,OBO,-2.0035,0.213352,0.00238894,1.00277 beta-lactamase_D250R,beta-lactamase_250,TEM-1,beta-lactamase,P62593,1.00277,NO,250,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.335,-2.84,0.505,5.72026,0.89,T,L,0.23,1.53,24.737,24.737,66.08,OAO,-1.85133,0.221079,0.00550899,1.00277 beta-lactamase_S96T,beta-lactamase_96,TEM-1,beta-lactamase,P62593,1.00277,NO,96,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.27,-2.436,0.166,5.29889,0.368,,b,0.25,0.39,32.348,32.348,73.78,HPP,-2.019,0.221079,0.00551835,1.00277 Pab1_I183C,Pab1_183,Pab1,Pab1,P04147,1.00277,NO,183,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.302,-4.508,3.206,,0.308,T,B,1,1.08,1.29,,75.56,HHA,-1.27167,0.175299,0.000574345,1.00277 beta-lactamase_0_H156A,beta-lactamase_0_156,TEM-1,beta-lactamase_0,P62593,1.00278,NO,156,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-3.156,-2.83,-0.326,,0.753,S,A,0.17,-0.6,23.367,23.367,77.62,ABH,-1.932,0.0500837,0.00468596,1.00278 beta-lactamase_156_I140W,beta-lactamase_156_140,TEM-1,beta-lactamase_156,P62593,1.00278,NO,140,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.733,-5.289,3.556,,0.128,H,A,0.48,0.41,1.16,,73.08,PHO,-1.48733,0.111618,0.00597777,1.00278 beta-lactamase_2500_T138A,beta-lactamase_2500_138,TEM-1,beta-lactamase_2500,P62593,1.00278,NO,138,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.506,-2.248,-0.258,,0.662,H,A,0.22,-0.03,30.445,30.445,73.78,HPP,-1.81233,0.361275,0.00487868,1.00278 beta-lactamase_39_I261Y,beta-lactamase_39_261,TEM-1,beta-lactamase_39,P62593,1.00278,NO,261,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.0495842,0.0123091,1.00278 beta-lactamase_625_K286I,beta-lactamase_625_286,TEM-1,beta-lactamase_625,P62593,1.00278,NO,286,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.213352,,1.00278 Pab1_E181D,Pab1_181,Pab1,Pab1,P04147,1.00278,NO,181,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.767,-1.933,0.166,,,,,,,1.395,,73.83,BAH,-1.575,0.175299,0.00107557,1.00278 beta-lactamase_156_R159S,beta-lactamase_156_159,TEM-1,beta-lactamase_156,P62593,1.00279,NO,159,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-0.94,-3.411,2.471,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.111618,0.00108472,1.00279 beta-lactamase_39_L89Q,beta-lactamase_39_89,TEM-1,beta-lactamase_39,P62593,1.00279,NO,89,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.096,-4.086,2.99,,0.168,T,A,0.55,0.63,3.233,,64.34,PHO,-1.75767,0.0495842,0.00207068,1.00279 beta-lactamase_39_R162F,beta-lactamase_39_162,TEM-1,beta-lactamase_39,P62593,1.00279,NO,162,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.016,-4.266,3.25,,0.124,S,B,1.2,-0.37,31.656,31.656,64.69,ABH,-1.25,0.0495842,0.000561334,1.00279 beta-lactamase_39_W163R,beta-lactamase_39_163,TEM-1,beta-lactamase_39,P62593,1.0028,NO,163,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-1.843,-2.51,0.667,,0.467,,B,0.47,-0.5,15.095,15.095,63.99,BHA,-1.269,0.0495842,0.00418955,1.0028 beta-lactamase_625_A222R,beta-lactamase_625_222,TEM-1,beta-lactamase_625,P62593,1.0028,NO,222,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.103,-4.005,1.902,,0.233,H,A,0.46,-0.25,1.448,,77.62,PHH,-1.63733,0.213352,0.00466094,1.0028 beta-lactamase_A148Y,beta-lactamase_148,TEM-1,beta-lactamase,P62593,1.0028,NO,148,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.757,-4.336,2.579,5.28111,0.379,H,A,0.52,-0.55,2.117,,72.73,PHH,-1.40167,0.221079,0.00547053,1.0028 beta-lactamase_K190G,beta-lactamase_190,TEM-1,beta-lactamase,P62593,1.0028,NO,190,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.994,-3.44,1.446,5.49163,0.371,H,A,1.82,0.16,29.753,29.753,77.62,BBH,-1.64167,0.221079,0.00574527,1.0028 beta-lactamase_P12C,beta-lactamase_12,TEM-1,beta-lactamase,P62593,1.0028,NO,12,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-2.016,-4.801,2.785,,,,,,,2.88,,72.73,HOH,-2.05167,0.221079,0.00241653,1.0028 beta-lactamase_156_M270Y,beta-lactamase_156_270,TEM-1,beta-lactamase_156,P62593,1.00281,NO,270,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.111618,0.00767762,1.00281 beta-lactamase_2500_H156F,beta-lactamase_2500_156,TEM-1,beta-lactamase_2500,P62593,1.00281,NO,156,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-3.156,-4.428,1.272,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.361275,0.00468596,1.00281 beta-lactamase_39_S51K,beta-lactamase_39_51,TEM-1,beta-lactamase_39,P62593,1.00281,NO,51,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.526,-3.459,1.933,,0.496,T,A,0.27,0.26,2.964,,72.73,PPO,-1.88467,0.0495842,0.00504821,1.00281 beta-lactamase_625_E108M,beta-lactamase_625_108,TEM-1,beta-lactamase_625,P62593,1.00281,NO,108,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.46,-4.775,3.315,,0.572,G,A,1.04,1.87,20.151,20.151,72.73,PAB,-1.437,0.213352,0.00413372,1.00281 beta-lactamase_156_F64Y,beta-lactamase_156_64,TEM-1,beta-lactamase_156,P62593,1.00282,NO,64,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-0.841,-3.037,2.196,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.111618,0.000947691,1.00282 beta-lactamase_156_T264M,beta-lactamase_156_264,TEM-1,beta-lactamase_156,P62593,1.00282,NO,264,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.111618,0.0119399,1.00282 beta-lactamase_625_T112R,beta-lactamase_625_112,TEM-1,beta-lactamase_625,P62593,1.00282,NO,112,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.186,-3.88,1.694,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.213352,0.00531334,1.00282 beta-lactamase_156_L219P,beta-lactamase_156_219,TEM-1,beta-lactamase_156,P62593,1.00283,NO,219,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.313,-4.214,2.901,,,I,A,0.55,-0.51,2.321,,74.48,HHB,-1.21533,0.111618,0.00664345,1.00283 beta-lactamase_39_Q86C,beta-lactamase_39_86,TEM-1,beta-lactamase_39,P62593,1.00283,NO,86,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.4,-5.132,2.732,,0.696,S,A,0.64,2.38,27.704,27.704,77.62,OPA,-1.61067,0.0495842,0.00450027,1.00283 beta-lactamase_39_V157D,beta-lactamase_39_157,TEM-1,beta-lactamase_39,P62593,1.00283,NO,157,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.751,-3.908,2.157,,0.308,S,a,0.44,-0.75,10.364,10.364,69.58,BHP,-2.00767,0.0495842,0.00506849,1.00283 beta-lactamase_625_Q86S,beta-lactamase_625_86,TEM-1,beta-lactamase_625,P62593,1.00283,NO,86,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.4,-2.711,0.311,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.213352,0.00450027,1.00283 beta-lactamase_L197L,beta-lactamase_197,TEM-1,beta-lactamase,P62593,1.00283,NO,197,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.853,-0.853,,5.19172,0.007,S,B,1.3,0.33,1.756,,60.14,HHP,-1.833,0.221079,0.00144602,1.00283 beta-lactamase_156_L111V,beta-lactamase_156_111,TEM-1,beta-lactamase_156,P62593,1.00284,NO,111,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.76,-1.731,-0.029,,0.328,T,A,0.55,0.93,2.26,,64.34,BHP,-1.884,0.111618,0.00480671,1.00284 beta-lactamase_2500_S96N,beta-lactamase_2500_96,TEM-1,beta-lactamase_2500,P62593,1.00284,NO,96,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.27,-3.037,0.767,,0.368,,b,0.27,0.39,32.348,32.348,73.78,HPP,-2.019,0.361275,0.00551835,1.00284 Pab1_D151F,Pab1_151,Pab1,Pab1,P04147,1.00285,NO,151,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.399,-4.281,1.882,,,,,,,,,,OAH,-1.51767,0.175299,0.00228155,1.00285 beta-lactamase_156_L135R,beta-lactamase_156_135,TEM-1,beta-lactamase_156,P62593,1.00286,NO,135,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.002,-4.002,3,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.111618,0.00244423,1.00286 beta-lactamase_156_L160G,beta-lactamase_156_160,TEM-1,beta-lactamase_156,P62593,1.00286,NO,160,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.977,-3.824,2.847,,0.022,,B,0.55,-0.6,1.095,,44.41,BHA,-0.936,0.111618,0.00193775,1.00286 beta-lactamase_156_T116P,beta-lactamase_156_116,TEM-1,beta-lactamase_156,P62593,1.00287,NO,116,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.28,-3.831,2.551,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.111618,0.00336175,1.00287 beta-lactamase_625_S256R,beta-lactamase_625_256,TEM-1,beta-lactamase_625,P62593,1.00287,NO,256,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.213352,0.00710634,1.00287 beta-lactamase_0_E145G,beta-lactamase_0_145,TEM-1,beta-lactamase_0,P62593,1.00288,NO,145,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.357,-1.279,-1.078,,0.545,H,A,1.04,0.79,1.199,,77.62,BAH,-2.069,0.0500837,0.00553285,1.00288 beta-lactamase_0_P60T,beta-lactamase_0_60,TEM-1,beta-lactamase_0,P62593,1.00288,NO,60,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-2.469,-3.483,1.014,,0.256,T,A,0.52,-0.56,3.653,,77.62,BOA,-1.97633,0.0500837,0.00521318,1.00288 beta-lactamase_156_Q37R,beta-lactamase_156_37,TEM-1,beta-lactamase_156,P62593,1.00288,NO,37,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.134,-2.096,-0.038,,0.613,H,A,0.64,1.98,12.052,12.052,73.08,APH,-2.06967,0.111618,0.00425833,1.00288 beta-lactamase_39_A278Q,beta-lactamase_39_278,TEM-1,beta-lactamase_39,P62593,1.00288,NO,278,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.0495842,0.0310297,1.00288 beta-lactamase_39_A282C,beta-lactamase_39_282,TEM-1,beta-lactamase_39,P62593,1.00288,NO,282,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.0495842,0.0449821,1.00288 beta-lactamase_39_I277Y,beta-lactamase_39_277,TEM-1,beta-lactamase_39,P62593,1.00288,NO,277,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.0495842,0.0169305,1.00288 beta-lactamase_39_S241F,beta-lactamase_39_241,TEM-1,beta-lactamase_39,P62593,1.00288,NO,241,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.0495842,0.00452736,1.00288 beta-lactamase_625_G265E,beta-lactamase_625_265,TEM-1,beta-lactamase_625,P62593,1.00288,NO,265,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.213352,0.00811926,1.00288 beta-lactamase_625_I140M,beta-lactamase_625_140,TEM-1,beta-lactamase_625,P62593,1.00288,NO,140,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.733,-4.137,2.404,,0.128,H,A,0.48,0.41,1.628,,73.08,PHO,-1.48733,0.213352,0.00597777,1.00288 beta-lactamase_625_K30A,beta-lactamase_625_30,TEM-1,beta-lactamase_625,P62593,1.00289,NO,30,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-2.307,-2.101,-0.206,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.213352,0.00448593,1.00289 beta-lactamase_156_R275C,beta-lactamase_156_275,TEM-1,beta-lactamase_156,P62593,1.0029,NO,275,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.111618,0.0141984,1.0029 beta-lactamase_39_G43C,beta-lactamase_39_43,TEM-1,beta-lactamase_39,P62593,1.0029,NO,43,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.62,-5.087,4.467,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.0495842,0.00120151,1.0029 beta-lactamase_625_G216S,beta-lactamase_625_216,TEM-1,beta-lactamase_625,P62593,1.0029,NO,216,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.477,-3.283,1.806,,0.437,I,A,0.29,-0.58,1.718,,74.48,HOO,-1.68067,0.213352,0.00639568,1.0029 beta-lactamase_625_L55N,beta-lactamase_625_55,TEM-1,beta-lactamase_625,P62593,1.0029,NO,55,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.86,-4.216,2.356,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.213352,0.00403741,1.0029 Pab1_S147T,Pab1_147,Pab1,Pab1,P04147,1.0029,NO,147,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.267,-1.993,0.726,,0.336,H,A,,0.56,,,,HPH,-1.43033,0.175299,0.000610856,1.0029 beta-lactamase_0_T27S,beta-lactamase_0_27,TEM-1,beta-lactamase_0,P62593,1.00291,NO,27,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.905,-2.606,0.701,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.0500837,0.00306559,1.00291 beta-lactamase_39_L218K,beta-lactamase_39_218,TEM-1,beta-lactamase_39,P62593,1.00291,NO,218,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.391,-2.186,0.795,,,I,b,0.55,-0.53,2.038,,74.48,OHH,-1.58867,0.0495842,0.00618274,1.00291 beta-lactamase_39_S283Q,beta-lactamase_39_283,TEM-1,beta-lactamase_39,P62593,1.00291,NO,283,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.0495842,0.0429138,1.00291 beta-lactamase_625_I206C,beta-lactamase_625_206,TEM-1,beta-lactamase_625,P62593,1.00291,NO,206,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-2.429,-4.969,2.54,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.213352,0.00528934,1.00291 beta-lactamase_625_L38Y,beta-lactamase_625_38,TEM-1,beta-lactamase_625,P62593,1.00291,NO,38,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.343,-2.956,1.613,,0.088,H,A,0.55,0.2,1.986,,64.34,PHO,-1.78033,0.213352,0.00373244,1.00291 beta-lactamase_2500_I171L,beta-lactamase_2500_171,TEM-1,beta-lactamase_2500,P62593,1.00292,NO,171,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-2.431,-1.98,-0.451,,0.361,,B,0.48,0.53,1.66,,77.62,HHO,-1.55533,0.361275,0.00623355,1.00292 beta-lactamase_39_L196G,beta-lactamase_39_196,TEM-1,beta-lactamase_39,P62593,1.00292,NO,196,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-2.478,-2.91,0.432,,0.518,S,A,0.55,1.35,12.152,12.152,77.62,AHH,-1.839,0.0495842,0.00512144,1.00292 beta-lactamase_39_T263S,beta-lactamase_39_263,TEM-1,beta-lactamase_39,P62593,1.00292,NO,263,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.0495842,0.0110582,1.00292 beta-lactamase_625_L196N,beta-lactamase_625_196,TEM-1,beta-lactamase_625,P62593,1.00292,NO,196,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-2.478,-3.953,1.475,,0.518,S,A,0.55,1.35,12.152,12.152,77.62,AHH,-1.839,0.213352,0.00512144,1.00292 beta-lactamase_156_G194S,beta-lactamase_156_194,TEM-1,beta-lactamase_156,P62593,1.00293,NO,194,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.396,-2.171,0.775,,0.276,S,b,0.29,0.36,1.346,,67.83,POA,-1.832,0.111618,0.00392163,1.00293 beta-lactamase_2500_Q86D,beta-lactamase_2500_86,TEM-1,beta-lactamase_2500,P62593,1.00293,NO,86,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.4,-2.27,-0.13,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.361275,0.00450027,1.00293 beta-lactamase_625_E210W,beta-lactamase_625_210,TEM-1,beta-lactamase_625,P62593,1.00293,NO,210,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.319,-5.437,3.118,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.213352,0.00663582,1.00293 beta-lactamase_2500_Q37I,beta-lactamase_2500_37,TEM-1,beta-lactamase_2500,P62593,1.00294,NO,37,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.134,-4.024,1.89,,0.613,H,A,0.64,1.98,1.318,,73.08,APH,-2.06967,0.361275,0.00425833,1.00294 beta-lactamase_P65P,beta-lactamase_65,TEM-1,beta-lactamase,P62593,1.00294,NO,65,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.894,-0.894,,5.59094,0.098,E,B,0.23,-0.62,0.623,,40.56,HOH,-1.03233,0.221079,0.00152776,1.00294 kka2_1:8_Q219G,kka2_1:8_219,Kka2,kka2_1:8,P00552,1.00294,NO,219,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-0.93,-3.41,2.48,,0.088,H,A,0.4,-0.85,0.897,,50,HPA,-1.05167,0.100394,0.00237913,1.00294 kka2_1:8_Q219G,kka2_1:8_219,Kka2,kka2_1:8,P00552,1.00294,NO,219,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-0.93,-3.41,2.48,,0.088,H,A,0.4,-0.85,0.897,,50,HPA,-1.05167,0.100394,0.00237913,1.00294 beta-lactamase_625_G253H,beta-lactamase_625_253,TEM-1,beta-lactamase_625,P62593,1.00295,NO,253,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.213352,0.00786358,1.00295 beta-lactamase_625_M66L,beta-lactamase_625_66,TEM-1,beta-lactamase_625,P62593,1.00295,NO,66,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.362,-1.674,0.312,,0.013,,A,0.55,-0.7,1.659,,73.08,OHH,-1.49567,0.213352,0.00412876,1.00295 beta-lactamase_39_L28V,beta-lactamase_39_28,TEM-1,beta-lactamase_39,P62593,1.00296,NO,28,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.579,-1.979,0.4,,0.277,H,A,0.55,-0.16,3.262,,93.01,PHH,-2.11333,0.0495842,0.00359321,1.00296 kka2_1:4_S40R,kka2_1:4_40,Kka2,kka2_1:4,P00552,1.00296,NO,40,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.645,-2.494,-0.151,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.168804,0.00693477,1.00296 kka2_1:8_G151W,kka2_1:8_151,Kka2,kka2_1:8,P00552,1.00296,NO,151,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.873,-5.3,4.427,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.100394,0.00339918,1.00296 kka2_1:8_G151W,kka2_1:8_151,Kka2,kka2_1:8,P00552,1.00296,NO,151,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.873,-5.3,4.427,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.100394,0.00339918,1.00296 Pab1_E175V,Pab1_175,Pab1,Pab1,P04147,1.00296,NO,175,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.055,-3.55,1.495,,,,,,,,,,AAA,-1.82667,0.175299,0.00203137,1.00296 PSD95pdz3_N381Q,PSD95pdz3_381,PSD95pdz3,PSD95pdz3,P31016,1.00296,NO,381,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-1.41,-3.356,1.946,5.66057,,,,,28.2162,,,,BPH,-1.37767,0.0758425,0.000265374,1.00296 beta-lactamase_39_A40D,beta-lactamase_39_40,TEM-1,beta-lactamase_39,P62593,1.00297,NO,40,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.402,-3.685,2.283,,0.155,S,B,0.46,0.21,0.783,,73.78,OHB,-1.40267,0.0495842,0.00490026,1.00297 beta-lactamase_625_A235M,beta-lactamase_625_235,TEM-1,beta-lactamase_625,P62593,1.00297,NO,235,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.266,-4.612,3.346,,0.32,E,B,0.46,-0.86,0.281,,50,OHO,-0.89,0.213352,0.00493474,1.00297 beta-lactamase_625_E166S,beta-lactamase_625_166,TEM-1,beta-lactamase_625,P62593,1.00297,NO,166,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.756,-2.582,0.826,,0.508,G,A,1.04,1.05,2.124,,73.08,OAH,-1.42233,0.213352,0.00512989,1.00297 beta-lactamase_625_G226F,beta-lactamase_625_226,TEM-1,beta-lactamase_625,P62593,1.00297,NO,226,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.461,-4.428,2.967,,0.701,T,l,0.29,-0.25,3.199,,74.48,HOH,-1.42933,0.213352,0.00665294,1.00297 beta-lactamase_625_S233G,beta-lactamase_625_233,TEM-1,beta-lactamase_625,P62593,1.00297,NO,233,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.886,-3.274,1.388,,0.016,E,B,0.27,-1.01,1.773,,77.62,BPO,-1.17267,0.213352,0.00311415,1.00297 beta-lactamase_Q97A,beta-lactamase_97,TEM-1,beta-lactamase,P62593,1.00297,NO,97,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.072,-2.26,0.188,6.30204,0.823,G,A,1.1,2.42,1.157,,77.62,PPP,-2.43833,0.221079,0.0045116,1.00297 Pab1_N162H,Pab1_162,Pab1,Pab1,P04147,1.00298,NO,162,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-2.313,-2.738,0.425,,0.681,T,A,,1.12,,,,APO,-1.532,0.175299,0.0030719,1.00298 WW_domain_T196F,WW_domain_196,Yap65,WW_domain,P46937,1.00298,NO,196,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.782,-4.042,2.26,5.5744,,,,,,5.836,,70.04,PPP,-1.732,0.153962,0.00421377,1.00298 beta-lactamase_156_H94R,beta-lactamase_156_94,TEM-1,beta-lactamase_156,P62593,1.00299,NO,94,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-2.5,-2.531,0.031,,0.776,,B,0.17,1.24,11.583,11.583,77.62,HBH,-1.872,0.111618,0.00389226,1.00299 beta-lactamase_156_I45M,beta-lactamase_156_45,TEM-1,beta-lactamase_156,P62593,1.00299,NO,45,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-2.421,-3.375,0.954,,,E,B,0.48,-0.3,2.256,,77.62,HHA,-2.30267,0.111618,0.00452842,1.00299 beta-lactamase_2500_T263V,beta-lactamase_2500_263,TEM-1,beta-lactamase_2500,P62593,1.00299,NO,263,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.361275,0.0110582,1.00299 beta-lactamase_39_G85R,beta-lactamase_39_85,TEM-1,beta-lactamase_39,P62593,1.00299,NO,85,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.011,-2.784,1.773,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.0495842,0.00252173,1.00299 beta-lactamase_625_Q204V,beta-lactamase_625_204,TEM-1,beta-lactamase_625,P62593,1.00299,NO,204,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-1.382,-3.595,2.213,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.213352,0.00364106,1.00299 beta-lactamase_625_T112Y,beta-lactamase_625_112,TEM-1,beta-lactamase_625,P62593,1.00299,NO,112,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.186,-4.422,2.236,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.213352,0.00531334,1.00299 beta-lactamase_156_G52L,beta-lactamase_156_52,TEM-1,beta-lactamase_156,P62593,1.003,NO,52,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.149,-3.755,2.606,,0.299,,l,0.29,-0.04,1.179,,64.69,POB,-1.66267,0.111618,0.00340138,1.003 beta-lactamase_39_T269F,beta-lactamase_39_269,TEM-1,beta-lactamase_39,P62593,1.003,NO,269,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.156,,,,0.646,H,A,0.53,0.4,3.889,,77.62,HPH,-1.96733,0.0495842,0.00950944,1.003 beta-lactamase_625_H151D,beta-lactamase_625_151,TEM-1,beta-lactamase_625,P62593,1.003,NO,151,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-2.96,-3.624,0.664,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.213352,0.00216946,1.003 beta-lactamase_625_Q37F,beta-lactamase_625_37,TEM-1,beta-lactamase_625,P62593,1.003,NO,37,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.134,-4.314,2.18,,0.613,H,A,0.64,1.98,1.318,,73.08,APH,-2.06967,0.213352,0.00425833,1.003 beta-lactamase_625_T116L,beta-lactamase_625_116,TEM-1,beta-lactamase_625,P62593,1.003,NO,116,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.28,-3.376,2.096,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.213352,0.00336175,1.003 beta-lactamase_625_T116M,beta-lactamase_625_116,TEM-1,beta-lactamase_625,P62593,1.003,NO,116,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.28,-4.634,3.354,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.213352,0.00336175,1.003 beta-lactamase_H156C,beta-lactamase_156,TEM-1,beta-lactamase,P62593,1.003,NO,156,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-3.156,-5.208,2.052,6.00284,0.753,S,A,0.72,-0.6,6.456,6.456,77.62,ABH,-1.932,0.221079,0.00468596,1.003 beta-lactamase_I45C,beta-lactamase_45,TEM-1,beta-lactamase,P62593,1.003,NO,45,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-2.421,-4.903,2.482,5.31505,,E,B,1,-0.3,2.256,,77.62,HHA,-2.30267,0.221079,0.00452842,1.003 beta-lactamase_156_P60F,beta-lactamase_156_60,TEM-1,beta-lactamase_156,P62593,1.00301,NO,60,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-2.469,-4.292,1.823,,0.256,T,A,0.52,-0.56,2.947,,77.62,BOA,-1.97633,0.111618,0.00521318,1.00301 beta-lactamase_156_S283P,beta-lactamase_156_283,TEM-1,beta-lactamase_156,P62593,1.00301,NO,283,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.111618,0.0429138,1.00301 kka2_1:2_L47V,kka2_1:2_47,Kka2,kka2_1:2,P00552,1.00301,NO,47,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.265,-2.308,1.043,,0.139,E,B,0.55,-0.86,2.369,,63.26,HHH,-1.77933,0.295029,0.00509386,1.00301 beta-lactamase_156_D36G,beta-lactamase_156_36,TEM-1,beta-lactamase_156,P62593,1.00302,NO,36,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.732,-2.829,0.097,,0.555,H,A,0.75,1.17,14.871,14.871,77.62,AAP,-1.91167,0.111618,0.00476483,1.00302 beta-lactamase_2500_H151S,beta-lactamase_2500_151,TEM-1,beta-lactamase_2500,P62593,1.00302,NO,151,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-2.96,-2.636,-0.324,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.361275,0.00216946,1.00302 beta-lactamase_39_L191T,beta-lactamase_39_191,TEM-1,beta-lactamase_39,P62593,1.00302,NO,191,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.087,-3.447,2.36,,,H,A,0.55,0.09,1.372,,63.29,BHH,-1.445,0.0495842,0.00263549,1.00302 beta-lactamase_156_A222P,beta-lactamase_156_222,TEM-1,beta-lactamase_156,P62593,1.00303,NO,222,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.103,-2.971,0.868,,0.233,H,A,0.46,-0.25,2.461,,77.62,PHH,-1.63733,0.111618,0.00466094,1.00303 beta-lactamase_39_Q88R,beta-lactamase_39_88,TEM-1,beta-lactamase_39,P62593,1.00303,NO,88,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.086,-2.458,0.372,,0.807,,B,0.64,2.03,11.108,11.108,77.62,APH,-1.53433,0.0495842,0.00504167,1.00303 Pab1_F149M,Pab1_149,Pab1,Pab1,P04147,1.00303,NO,149,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.149,-4.072,2.923,,0.183,T,A,1.33,1.09,,,,HHO,-1.27767,0.175299,0.000325688,1.00303 Pab1_P135A,Pab1_135,Pab1,Pab1,P04147,1.00303,NO,135,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.457,-1.942,0.485,,,,,,,6.41,,81.8,BOA,-1.53367,0.175299,0.00148028,1.00303 beta-lactamase_156_S283A,beta-lactamase_156_283,TEM-1,beta-lactamase_156,P62593,1.00304,NO,283,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.111618,0.0429138,1.00304 beta-lactamase_2500_E108G,beta-lactamase_2500_108,TEM-1,beta-lactamase_2500,P62593,1.00304,NO,108,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.46,-2.454,0.994,,0.572,G,A,1.04,1.87,1.147,,72.73,PAB,-1.437,0.361275,0.00413372,1.00304 beta-lactamase_39_L167S,beta-lactamase_39_167,TEM-1,beta-lactamase_39,P62593,1.00304,NO,167,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.138,-2.747,1.609,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.0495842,0.00303566,1.00304 beta-lactamase_T187T,beta-lactamase_187,TEM-1,beta-lactamase,P62593,1.00304,NO,187,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.401,-1.401,,5.11453,0.007,H,A,0.3,-1.19,1.751,,67.48,PPH,-1.69633,0.221079,0.00491782,1.00304 beta-lactamase_39_S51H,beta-lactamase_39_51,TEM-1,beta-lactamase_39,P62593,1.00305,NO,51,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.526,-4.622,3.096,,0.496,T,A,0.27,0.26,2.964,,72.73,PPO,-1.88467,0.0495842,0.00504821,1.00305 beta-lactamase_156_E61R,beta-lactamase_156_61,TEM-1,beta-lactamase_156,P62593,1.00306,NO,61,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.115,-3.845,1.73,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.111618,0.00440955,1.00306 beta-lactamase_625_G265L,beta-lactamase_625_265,TEM-1,beta-lactamase_625,P62593,1.00307,NO,265,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.213352,0.00811926,1.00307 beta-lactamase_156_A246C,beta-lactamase_156_246,TEM-1,beta-lactamase_156,P62593,1.00308,NO,246,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.121,-3.242,1.121,,0.01,E,B,0.46,-1.01,1.959,,73.78,HHH,-1.55633,0.111618,0.00569458,1.00308 beta-lactamase_156_A282Y,beta-lactamase_156_282,TEM-1,beta-lactamase_156,P62593,1.00308,NO,282,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.111618,0.0449821,1.00308 beta-lactamase_156_E195R,beta-lactamase_156_195,TEM-1,beta-lactamase_156,P62593,1.00308,NO,195,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.186,-3.074,0.888,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.111618,0.00496565,1.00308 beta-lactamase_39_G194W,beta-lactamase_39_194,TEM-1,beta-lactamase_39,P62593,1.00308,NO,194,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.396,-5.42,4.024,,0.276,S,b,0.29,0.36,4.852,,67.83,POA,-1.832,0.0495842,0.00392163,1.00308 beta-lactamase_625_A222T,beta-lactamase_625_222,TEM-1,beta-lactamase_625,P62593,1.00308,NO,222,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.103,-2.805,0.702,,0.233,H,A,0.46,-0.25,1.448,,77.62,PHH,-1.63733,0.213352,0.00466094,1.00308 beta-lactamase_625_P60K,beta-lactamase_625_60,TEM-1,beta-lactamase_625,P62593,1.00308,NO,60,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-2.469,-3.557,1.088,,0.256,T,A,0.52,-0.56,3.653,,77.62,BOA,-1.97633,0.213352,0.00521318,1.00308 beta-lactamase_156_A182I,beta-lactamase_156_182,TEM-1,beta-lactamase_156,P62593,1.00309,NO,182,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.777,-3.851,2.074,,0.136,H,A,0.46,-0.66,16.784,16.784,93.01,OHH,-1.27367,0.111618,0.00559099,1.00309 beta-lactamase_156_P181S,beta-lactamase_156_181,TEM-1,beta-lactamase_156,P62593,1.00309,NO,181,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.813,-3.349,2.536,,,H,A,0.52,-1.14,1.078,,61.54,HOH,-1.795,0.111618,0.000703122,1.00309 beta-lactamase_39_L38Q,beta-lactamase_39_38,TEM-1,beta-lactamase_39,P62593,1.00309,NO,38,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.343,-4.155,2.812,,0.088,H,A,0.55,0.2,17.089,17.089,64.34,PHO,-1.78033,0.0495842,0.00373244,1.00309 beta-lactamase_625_K32H,beta-lactamase_625_32,TEM-1,beta-lactamase_625,P62593,1.00309,NO,32,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.984,-4.632,2.648,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.213352,0.00401283,1.00309 beta-lactamase_625_P255L,beta-lactamase_625_255,TEM-1,beta-lactamase_625,P62593,1.00309,NO,255,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.213352,0.00499612,1.00309 beta-lactamase_156_I93H,beta-lactamase_156_93,TEM-1,beta-lactamase_156,P62593,1.0031,NO,93,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.401,-5.004,3.603,,0.128,E,B,0.48,0.44,1.524,,67.83,BHB,-1.873,0.111618,0.00527066,1.0031 beta-lactamase_625_D174S,beta-lactamase_625_174,TEM-1,beta-lactamase_625,P62593,1.0031,NO,174,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.738,-3.161,2.423,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.213352,0.00125633,1.0031 beta-lactamase_P60S,beta-lactamase_60,TEM-1,beta-lactamase,P62593,1.0031,NO,60,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-2.469,-2.362,-0.107,5.51353,0.256,T,A,0.73,-0.56,3.653,,77.62,BOA,-1.97633,0.221079,0.00521318,1.0031 beta-lactamase_156_P250L,beta-lactamase_156_250,TEM-1,beta-lactamase_156,P62593,1.00311,NO,250,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.111618,0.00550899,1.00311 beta-lactamase_156_P60N,beta-lactamase_156_60,TEM-1,beta-lactamase_156,P62593,1.00311,NO,60,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-2.469,-3.804,1.335,,0.256,T,A,0.52,-0.56,2.947,,77.62,BOA,-1.97633,0.111618,0.00521318,1.00311 beta-lactamase_625_K53Q,beta-lactamase_625_53,TEM-1,beta-lactamase_625,P62593,1.00311,NO,53,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-2.313,-2.642,0.329,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.213352,0.00383383,1.00311 beta-lactamase_156_M66S,beta-lactamase_156_66,TEM-1,beta-lactamase_156,P62593,1.00312,NO,66,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.362,-3.571,2.209,,0.013,,A,0.55,-0.7,1.94,,73.08,OHH,-1.49567,0.111618,0.00412876,1.00312 kka2_1:4_A41F,kka2_1:4_41,Kka2,kka2_1:4,P00552,1.00312,NO,41,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.879,-3.42,1.541,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.168804,0.00543332,1.00312 kka2_1:8_Q219A,kka2_1:8_219,Kka2,kka2_1:8,P00552,1.00312,NO,219,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-0.93,-3.129,2.199,,0.088,H,A,0.4,-0.85,0.897,,50,HPA,-1.05167,0.100394,0.00237913,1.00312 kka2_1:8_Q219A,kka2_1:8_219,Kka2,kka2_1:8,P00552,1.00312,NO,219,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-0.93,-3.129,2.199,,0.088,H,A,0.4,-0.85,0.897,,50,HPA,-1.05167,0.100394,0.00237913,1.00312 Pab1_N187R,Pab1_187,Pab1,Pab1,P04147,1.00312,NO,187,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-1.224,-3.446,2.222,,0.456,S,b,,1.87,,,,HPO,-1.272,0.175299,0.00083165,1.00312 beta-lactamase_156_K32N,beta-lactamase_156_32,TEM-1,beta-lactamase_156,P62593,1.00313,NO,32,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.984,-2.965,0.981,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.111618,0.00401283,1.00313 beta-lactamase_39_E145K,beta-lactamase_39_145,TEM-1,beta-lactamase_39,P62593,1.00313,NO,145,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.357,-3.472,1.115,,0.545,H,A,1.04,0.79,1.199,,77.62,BAH,-2.069,0.0495842,0.00553285,1.00313 beta-lactamase_625_S266G,beta-lactamase_625_266,TEM-1,beta-lactamase_625,P62593,1.00313,NO,266,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.213352,0.0140785,1.00313 beta-lactamase_E237R,beta-lactamase_237,TEM-1,beta-lactamase,P62593,1.00313,NO,237,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.058,-2.839,0.781,5.42877,0.583,S,B,1.62,1.2,2.144,,77.62,OAB,-1.61467,0.221079,0.0048626,1.00313 beta-lactamase_K284A,beta-lactamase_284,TEM-1,beta-lactamase,P62593,1.00313,NO,284,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.981,-3.125,1.144,6.30084,0.848,H,A,1.82,0.67,1.931,,77.62,HBB,-1.82133,0.221079,0.0686156,1.00313 beta-lactamase_L160I,beta-lactamase_160,TEM-1,beta-lactamase,P62593,1.00313,NO,160,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.977,-2.155,1.178,5.32068,0.022,,B,1.75,-0.6,0.895,,44.41,BHA,-0.936,0.221079,0.00193775,1.00313 beta-lactamase_R189H,beta-lactamase_189,TEM-1,beta-lactamase,P62593,1.00313,NO,189,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.844,-2.544,0.7,5.74877,0.278,H,A,0.68,1.01,1.512,,72.73,HBB,-1.668,0.221079,0.0050699,1.00313 beta-lactamase_T112G,beta-lactamase_112,TEM-1,beta-lactamase,P62593,1.00313,NO,112,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.186,-1.822,-0.364,6.47162,0.921,T,A,0.77,1.06,2.04,,73.78,HPA,-1.925,0.221079,0.00531334,1.00313 beta-lactamase_T186N,beta-lactamase_186,TEM-1,beta-lactamase,P62593,1.00313,NO,186,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.522,-3.756,1.234,5.07364,0.396,H,A,0.3,-0.28,2.144,,77.62,HPP,-1.77633,0.221079,0.00485034,1.00313 beta-lactamase_T186Y,beta-lactamase_186,TEM-1,beta-lactamase,P62593,1.00313,NO,186,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.522,-4.364,1.842,5.07364,0.396,H,A,0.3,-0.28,2.144,,77.62,HPP,-1.77633,0.221079,0.00485034,1.00313 beta-lactamase_0_I54Y,beta-lactamase_0_54,TEM-1,beta-lactamase_0,P62593,1.00314,NO,54,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-2.838,-4.264,1.426,,0.669,E,B,0.48,-0.14,0.541,,73.78,BHH,-2.337,0.0500837,0.00403589,1.00314 beta-lactamase_156_E238H,beta-lactamase_156_238,TEM-1,beta-lactamase_156,P62593,1.00314,NO,238,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.111618,0.00743256,1.00314 beta-lactamase_39_G141N,beta-lactamase_39_141,TEM-1,beta-lactamase_39,P62593,1.00314,NO,141,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.828,-3.472,2.644,,0.575,T,l,0.29,-0.28,0.722,,64.69,HOO,-1.08933,0.0495842,0.0012419,1.00314 beta-lactamase_39_G39T,beta-lactamase_39_39,TEM-1,beta-lactamase_39,P62593,1.00314,NO,39,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.864,-2.931,1.067,,0.701,T,L,0.29,0.47,1.454,,77.62,HOH,-1.53633,0.0495842,0.00487611,1.00314 beta-lactamase_39_L79I,beta-lactamase_39_79,TEM-1,beta-lactamase_39,P62593,1.00314,NO,79,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.842,-2.934,2.092,,0.007,H,A,0.55,-0.16,0.823,,50.35,HHP,-1.44333,0.0495842,0.000947397,1.00314 beta-lactamase_625_P25L,beta-lactamase_625_25,TEM-1,beta-lactamase_625,P62593,1.00314,NO,25,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.526,-3.586,2.06,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.213352,0.00347571,1.00314 beta-lactamase_2500_P60D,beta-lactamase_2500_60,TEM-1,beta-lactamase_2500,P62593,1.00315,NO,60,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-2.469,-3.676,1.207,,0.256,T,A,0.52,-0.56,1.581,,77.62,BOA,-1.97633,0.361275,0.00521318,1.00315 beta-lactamase_39_R202W,beta-lactamase_39_202,TEM-1,beta-lactamase_39,P62593,1.00315,NO,202,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.292,-5.342,4.05,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.0495842,0.00321899,1.00315 beta-lactamase_156_K32A,beta-lactamase_156_32,TEM-1,beta-lactamase_156,P62593,1.00316,NO,32,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.984,-2.363,0.379,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.111618,0.00401283,1.00316 beta-lactamase_156_Q88G,beta-lactamase_156_88,TEM-1,beta-lactamase_156,P62593,1.00316,NO,88,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.086,-3.448,1.362,,0.807,,B,0.64,2.03,0.911,,77.62,APH,-1.53433,0.111618,0.00504167,1.00316 beta-lactamase_39_G85A,beta-lactamase_39_85,TEM-1,beta-lactamase_39,P62593,1.00316,NO,85,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.011,-3.043,2.032,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.0495842,0.00252173,1.00316 beta-lactamase_39_P172H,beta-lactamase_39_172,TEM-1,beta-lactamase_39,P62593,1.00316,NO,172,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.998,-4.746,3.748,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.0495842,0.00312594,1.00316 beta-lactamase_39_R176V,beta-lactamase_39_176,TEM-1,beta-lactamase_39,P62593,1.00316,NO,176,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-0.863,-3.754,2.891,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.0495842,0.00105554,1.00316 beta-lactamase_39_R202T,beta-lactamase_39_202,TEM-1,beta-lactamase_39,P62593,1.00316,NO,202,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.292,-3.438,2.146,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.0495842,0.00321899,1.00316 beta-lactamase_625_L248C,beta-lactamase_625_248,TEM-1,beta-lactamase_625,P62593,1.00316,NO,248,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.213352,0.00428493,1.00316 beta-lactamase_625_S233T,beta-lactamase_625_233,TEM-1,beta-lactamase_625,P62593,1.00316,NO,233,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.886,-1.229,-0.657,,0.016,E,B,0.27,-1.01,1.773,,77.62,BPO,-1.17267,0.213352,0.00311415,1.00316 kka2_1:8_S40L,kka2_1:8_40,Kka2,kka2_1:8,P00552,1.00317,NO,40,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.645,-3.085,0.44,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.100394,0.00693477,1.00317 kka2_1:8_S40L,kka2_1:8_40,Kka2,kka2_1:8,P00552,1.00317,NO,40,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.645,-3.085,0.44,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.100394,0.00693477,1.00317 beta-lactamase_0_L218W,beta-lactamase_0_218,TEM-1,beta-lactamase_0,P62593,1.00318,NO,218,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.391,-5.26,3.869,,,I,b,0.55,-0.53,28.707,28.707,74.48,OHH,-1.58867,0.0500837,0.00618274,1.00318 beta-lactamase_156_Q86H,beta-lactamase_156_86,TEM-1,beta-lactamase_156,P62593,1.00318,NO,86,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.4,-4.718,2.318,,0.696,S,A,0.64,2.38,27.704,27.704,77.62,OPA,-1.61067,0.111618,0.00450027,1.00318 beta-lactamase_2500_N50H,beta-lactamase_2500_50,TEM-1,beta-lactamase_2500,P62593,1.00318,NO,50,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-2.979,-3.33,0.351,,0.912,T,A,0.61,1.24,1.581,,77.62,HPP,-2.134,0.361275,0.0047211,1.00318 beta-lactamase_39_G142Q,beta-lactamase_39_142,TEM-1,beta-lactamase_39,P62593,1.00318,NO,142,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.707,-4.087,3.38,,0.034,,p,0.29,-0.64,1.947,,64.69,OOO,-0.834,0.0495842,0.00060149,1.00318 beta-lactamase_39_Y44V,beta-lactamase_39_44,TEM-1,beta-lactamase_39,P62593,1.00318,NO,44,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-2.547,-1.805,-0.742,,,E,B,0.21,-0.45,2.683,,73.78,OHH,-1.86267,0.0495842,0.00426364,1.00318 kka2_1:4_K138H,kka2_1:4_138,Kka2,kka2_1:4,P00552,1.00318,NO,138,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-2.5,-3.509,1.009,,0.594,H,A,1.3,0.98,21.267,21.267,71.59,HBB,-2.48833,0.168804,0.00628542,1.00318 beta-lactamase_156_A84V,beta-lactamase_156_84,TEM-1,beta-lactamase_156,P62593,1.00319,NO,84,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.651,-2.943,1.292,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.111618,0.00503822,1.00319 beta-lactamase_156_P250N,beta-lactamase_156_250,TEM-1,beta-lactamase_156,P62593,1.00319,NO,250,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.111618,0.00550899,1.00319 beta-lactamase_156_Q88R,beta-lactamase_156_88,TEM-1,beta-lactamase_156,P62593,1.00319,NO,88,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.086,-2.458,0.372,,0.807,,B,0.64,2.03,0.911,,77.62,APH,-1.53433,0.111618,0.00504167,1.00319 beta-lactamase_156_W163S,beta-lactamase_156_163,TEM-1,beta-lactamase_156,P62593,1.00319,NO,163,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-1.843,-3.614,1.771,,0.467,,B,0.47,-0.5,15.095,15.095,63.99,BHA,-1.269,0.111618,0.00418955,1.00319 beta-lactamase_625_M180L,beta-lactamase_625_180,TEM-1,beta-lactamase_625,P62593,1.00319,NO,180,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-2.795,-3.19,0.395,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.213352,0.00552048,1.00319 beta-lactamase_625_S51A,beta-lactamase_625_51,TEM-1,beta-lactamase_625,P62593,1.00319,NO,51,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.526,-2.32,0.794,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.213352,0.00504821,1.00319 beta-lactamase_D269G,beta-lactamase_269,TEM-1,beta-lactamase,P62593,1.00319,NO,269,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.156,-3.353,1.197,5.47645,0.646,H,A,0.23,0.4,21.796,21.796,77.62,HAA,-1.96733,0.221079,0.00950944,1.00319 beta-lactamase_H94Q,beta-lactamase_94,TEM-1,beta-lactamase,P62593,1.00319,NO,94,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-2.5,-3.155,0.655,6.1507,0.776,,B,0.63,1.24,1.176,,77.62,HBH,-1.872,0.221079,0.00389226,1.00319 beta-lactamase_S240A,beta-lactamase_240,TEM-1,beta-lactamase,P62593,1.00319,NO,240,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.537,-1.935,0.398,4.75024,,,B,0.74,-0.74,0.357,,65.38,OPB,-1.263,0.221079,0.00591201,1.00319 gb1_T244H,gb1_244,gb1,gb1,P06654,1.00319,NO,244,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.637,-4.597,2.96,,,,,,,0.202,,11.83,PPA,-1.92567,0.177985,0.00222755,1.00319 beta-lactamase_0_T269F,beta-lactamase_0_269,TEM-1,beta-lactamase_0,P62593,1.0032,NO,269,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.0500837,0.00950944,1.0032 beta-lactamase_156_I245V,beta-lactamase_156_245,TEM-1,beta-lactamase_156,P62593,1.0032,NO,245,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.111618,0.00391032,1.0032 beta-lactamase_156_Y44H,beta-lactamase_156_44,TEM-1,beta-lactamase_156,P62593,1.0032,NO,44,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-2.547,-4.769,2.222,,,E,B,0.21,-0.45,2.184,,73.78,OHH,-1.86267,0.111618,0.00426364,1.0032 beta-lactamase_625_A40T,beta-lactamase_625_40,TEM-1,beta-lactamase_625,P62593,1.0032,NO,40,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.402,-2.653,1.251,,0.155,S,B,0.46,0.21,1.357,,73.78,OHB,-1.40267,0.213352,0.00490026,1.0032 beta-lactamase_625_D36Q,beta-lactamase_625_36,TEM-1,beta-lactamase_625,P62593,1.0032,NO,36,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.732,-2.234,-0.498,,0.555,H,A,0.75,1.17,2.26,,77.62,AAP,-1.91167,0.213352,0.00476483,1.0032 beta-lactamase_625_V157I,beta-lactamase_625_157,TEM-1,beta-lactamase_625,P62593,1.0032,NO,157,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.751,-2.621,0.87,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.213352,0.00506849,1.0032 beta-lactamase_Q97I,beta-lactamase_97,TEM-1,beta-lactamase,P62593,1.0032,NO,97,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.072,-4.072,2,6.30204,0.823,G,A,1.1,2.42,1.157,,77.62,PPP,-2.43833,0.221079,0.0045116,1.0032 beta-lactamase_S122I,beta-lactamase_122,TEM-1,beta-lactamase,P62593,1.0032,NO,122,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.406,-3.138,0.732,4.87767,0.352,H,A,0.73,-0.54,1.581,,77.62,OPH,-1.39767,0.221079,0.00497825,1.0032 beta-lactamase_156_S266C,beta-lactamase_156_266,TEM-1,beta-lactamase_156,P62593,1.00321,NO,266,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.111618,0.0140785,1.00321 beta-lactamase_2500_L191M,beta-lactamase_2500_191,TEM-1,beta-lactamase_2500,P62593,1.00321,NO,191,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.087,-4.016,2.929,,,H,A,0.55,0.09,1.703,,63.29,BHH,-1.445,0.361275,0.00263549,1.00321 beta-lactamase_39_S233C,beta-lactamase_39_233,TEM-1,beta-lactamase_39,P62593,1.00321,NO,233,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.886,-4.789,2.903,,0.016,E,B,0.27,-1.01,5.361,,77.62,BPO,-1.17267,0.0495842,0.00311415,1.00321 beta-lactamase_2500_D207S,beta-lactamase_2500_207,TEM-1,beta-lactamase_2500,P62593,1.00322,NO,207,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.064,-2.656,0.592,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.361275,0.00592942,1.00322 beta-lactamase_625_T263I,beta-lactamase_625_263,TEM-1,beta-lactamase_625,P62593,1.00322,NO,263,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.213352,0.0110582,1.00322 beta-lactamase_2500_E26A,beta-lactamase_2500_26,TEM-1,beta-lactamase_2500,P62593,1.00323,NO,26,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.454,-2.207,-0.247,,0.54,H,A,1.04,0.98,0.49,,93.01,OAP,-1.96167,0.361275,0.00297948,1.00323 beta-lactamase_2500_P60Q,beta-lactamase_2500_60,TEM-1,beta-lactamase_2500,P62593,1.00323,NO,60,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-2.469,-3.986,1.517,,0.256,T,A,0.52,-0.56,1.581,,77.62,BOA,-1.97633,0.361275,0.00521318,1.00323 kka2_1:2_A9C,kka2_1:2_9,Kka2,kka2_1:2,P00552,1.00323,NO,9,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.079,-4.697,2.618,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.295029,0.00273264,1.00323 beta-lactamase_156_F70M,beta-lactamase_156_70,TEM-1,beta-lactamase_156,P62593,1.00324,NO,70,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.169,-3.002,1.833,,,H,A,0.58,-1.34,1.918,,63.99,PHB,-0.980667,0.111618,0.00193499,1.00324 beta-lactamase_39_G194P,beta-lactamase_39_194,TEM-1,beta-lactamase_39,P62593,1.00324,NO,194,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.396,-3.912,2.516,,0.276,S,b,0.29,0.36,4.852,,67.83,POA,-1.832,0.0495842,0.00392163,1.00324 beta-lactamase_625_K32A,beta-lactamase_625_32,TEM-1,beta-lactamase_625,P62593,1.00324,NO,32,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.984,-2.363,0.379,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.213352,0.00401283,1.00324 beta-lactamase_39_L191A,beta-lactamase_39_191,TEM-1,beta-lactamase_39,P62593,1.00325,NO,191,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.087,-2.236,1.149,,,H,A,0.55,0.09,1.372,,63.29,BHH,-1.445,0.0495842,0.00263549,1.00325 beta-lactamase_625_E166R,beta-lactamase_625_166,TEM-1,beta-lactamase_625,P62593,1.00325,NO,166,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.756,-3.805,2.049,,0.508,G,A,1.04,1.05,2.124,,73.08,OAH,-1.42233,0.213352,0.00512989,1.00325 beta-lactamase_625_N173K,beta-lactamase_625_173,TEM-1,beta-lactamase_625,P62593,1.00325,NO,173,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-2.663,-2.711,0.048,,1.044,T,l,0.61,1.25,1.426,,77.62,OPA,-1.46633,0.213352,0.0033769,1.00325 beta-lactamase_A246I,beta-lactamase_246,TEM-1,beta-lactamase,P62593,1.00325,NO,246,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.121,-2.179,0.058,4.78979,0.01,E,B,0.52,-1.01,1.26,,73.78,HHH,-1.55633,0.221079,0.00569458,1.00325 kka2_1:8_R239D,kka2_1:8_239,Kka2,kka2_1:8,P00552,1.00325,NO,239,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.949,-2.803,-0.146,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.100394,0.00835326,1.00325 kka2_1:8_R239D,kka2_1:8_239,Kka2,kka2_1:8,P00552,1.00325,NO,239,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.949,-2.803,-0.146,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.100394,0.00835326,1.00325 beta-lactamase_156_Q37T,beta-lactamase_156_37,TEM-1,beta-lactamase_156,P62593,1.00326,NO,37,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.134,-2.508,0.374,,0.613,H,A,0.64,1.98,12.052,12.052,73.08,APH,-2.06967,0.111618,0.00425833,1.00326 beta-lactamase_39_L150I,beta-lactamase_39_150,TEM-1,beta-lactamase_39,P62593,1.00326,NO,150,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.326,-3.18,1.854,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.0495842,0.00463171,1.00326 beta-lactamase_39_N274C,beta-lactamase_39_274,TEM-1,beta-lactamase_39,P62593,1.00326,NO,274,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.0495842,0.0110418,1.00326 beta-lactamase_625_L47I,beta-lactamase_625_47,TEM-1,beta-lactamase_625,P62593,1.00326,NO,47,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.876,-2.384,0.508,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.213352,0.00439844,1.00326 beta-lactamase_39_G265P,beta-lactamase_39_265,TEM-1,beta-lactamase_39,P62593,1.00327,NO,265,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.0495842,0.00811926,1.00327 beta-lactamase_625_G39H,beta-lactamase_625_39,TEM-1,beta-lactamase_625,P62593,1.00327,NO,39,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.864,-3.359,1.495,,0.701,T,L,0.29,0.47,29.926,29.926,77.62,HOH,-1.53633,0.213352,0.00487611,1.00327 beta-lactamase_625_L199W,beta-lactamase_625_199,TEM-1,beta-lactamase_625,P62593,1.00327,NO,199,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-2.942,-5.582,2.64,,0.832,H,A,0.55,0.42,1.552,,77.62,PHH,-2.32933,0.213352,0.0048649,1.00327 beta-lactamase_625_M66C,beta-lactamase_625_66,TEM-1,beta-lactamase_625,P62593,1.00327,NO,66,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.362,-4.734,3.372,,0.013,,A,0.55,-0.7,1.659,,73.08,OHH,-1.49567,0.213352,0.00412876,1.00327 beta-lactamase_156_K286I,beta-lactamase_156_286,TEM-1,beta-lactamase_156,P62593,1.00328,NO,286,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.111618,,1.00328 beta-lactamase_2500_E238C,beta-lactamase_2500_238,TEM-1,beta-lactamase_2500,P62593,1.00328,NO,238,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.361275,0.00743256,1.00328 beta-lactamase_2500_K109L,beta-lactamase_2500_109,TEM-1,beta-lactamase_2500,P62593,1.00328,NO,109,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.734,-2.969,1.235,,0.787,G,A,2.34,2.21,0.998,,72.73,ABB,-1.63333,0.361275,0.00462493,1.00328 beta-lactamase_39_A34S,beta-lactamase_39_34,TEM-1,beta-lactamase_39,P62593,1.00328,NO,34,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.059,-2.213,0.154,,,H,A,0.46,-0.54,13.292,13.292,73.78,AHA,-1.74967,0.0495842,0.00407913,1.00328 PSD95pdz3_G335I,PSD95pdz3_335,PSD95pdz3,PSD95pdz3,P31016,1.00328,NO,335,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.008,-3.917,2.909,4.76223,,,,,22.4225,,,,AOH,-1.34733,0.0758425,0.000900493,1.00328 beta-lactamase_2500_G194D,beta-lactamase_2500_194,TEM-1,beta-lactamase_2500,P62593,1.00329,NO,194,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.396,-2.314,0.918,,0.276,S,b,0.29,0.36,3.593,,67.83,POA,-1.832,0.361275,0.00392163,1.00329 beta-lactamase_2500_S122H,beta-lactamase_2500_122,TEM-1,beta-lactamase_2500,P62593,1.00329,NO,122,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.406,-2.676,0.27,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.361275,0.00497825,1.00329 beta-lactamase_39_A268Y,beta-lactamase_39_268,TEM-1,beta-lactamase_39,P62593,1.00329,NO,268,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.0495842,0.0102525,1.00329 beta-lactamase_39_V260I,beta-lactamase_39_260,TEM-1,beta-lactamase_39,P62593,1.00329,NO,260,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.0495842,0.00471757,1.00329 beta-lactamase_E195D,beta-lactamase_195,TEM-1,beta-lactamase,P62593,1.00329,NO,195,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.186,-1.979,-0.207,7.28489,1.016,S,A,1.52,0.85,2.583,,77.62,OAH,-2.02,0.221079,0.00496565,1.00329 beta-lactamase_E270K,beta-lactamase_270,TEM-1,beta-lactamase,P62593,1.00329,NO,270,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.723,-2.402,0.679,5.33196,0.422,H,A,0.52,1.15,1.745,,64.34,AAB,-1.70933,0.221079,0.00767762,1.00329 beta-lactamase_T138G,beta-lactamase_138,TEM-1,beta-lactamase,P62593,1.00329,NO,138,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.506,-2.767,0.261,5.52585,0.662,H,A,0.3,-0.03,30.445,30.445,73.78,HPP,-1.81233,0.221079,0.00487868,1.00329 PSD95pdz3_Q358A,PSD95pdz3_358,PSD95pdz3,PSD95pdz3,P31016,1.00329,NO,358,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-1.699,-2.759,1.06,5.21282,,,,,14.8844,,,,APH,-1.531,0.0758425,0.000594893,1.00329 beta-lactamase_156_A123T,beta-lactamase_156_123,TEM-1,beta-lactamase_156,P62593,1.0033,NO,123,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.834,-3.222,2.388,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.111618,0.0010157,1.0033 beta-lactamase_39_L38S,beta-lactamase_39_38,TEM-1,beta-lactamase_39,P62593,1.0033,NO,38,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.343,-2.597,1.254,,0.088,H,A,0.55,0.2,17.089,17.089,64.34,PHO,-1.78033,0.0495842,0.00373244,1.0033 beta-lactamase_625_A200W,beta-lactamase_625_200,TEM-1,beta-lactamase_625,P62593,1.0033,NO,200,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.878,-5.525,3.647,,0.757,H,A,0.46,-0.19,12.672,12.672,77.62,HHP,-2.001,0.213352,0.0060056,1.0033 beta-lactamase_156_R91H,beta-lactamase_156_91,TEM-1,beta-lactamase_156,P62593,1.00331,NO,91,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.392,-4.422,3.03,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.111618,0.00380226,1.00331 beta-lactamase_39_T264Y,beta-lactamase_39_264,TEM-1,beta-lactamase_39,P62593,1.00331,NO,264,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.0495842,0.0119399,1.00331 beta-lactamase_156_R63W,beta-lactamase_156_63,TEM-1,beta-lactamase_156,P62593,1.00332,NO,63,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-0.943,-5.32,4.377,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.111618,0.00126938,1.00332 beta-lactamase_39_P25R,beta-lactamase_39_25,TEM-1,beta-lactamase_39,P62593,1.00332,NO,25,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.526,-3.8,2.274,,0.624,H,A,0.52,0.14,1.157,,73.08,BOA,-2.15367,0.0495842,0.00347571,1.00332 beta-lactamase_625_G194L,beta-lactamase_625_194,TEM-1,beta-lactamase_625,P62593,1.00332,NO,194,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.396,-3.731,2.335,,0.276,S,b,0.29,0.36,3.593,,67.83,POA,-1.832,0.213352,0.00392163,1.00332 beta-lactamase_625_K30L,beta-lactamase_625_30,TEM-1,beta-lactamase_625,P62593,1.00332,NO,30,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-2.307,-3.404,1.097,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.213352,0.00448593,1.00332 beta-lactamase_625_L196G,beta-lactamase_625_196,TEM-1,beta-lactamase_625,P62593,1.00332,NO,196,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-2.478,-2.91,0.432,,0.518,S,A,0.55,1.35,12.152,12.152,77.62,AHH,-1.839,0.213352,0.00512144,1.00332 beta-lactamase_625_R41L,beta-lactamase_625_41,TEM-1,beta-lactamase_625,P62593,1.00332,NO,41,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-0.942,-3.384,2.442,,0.321,E,B,1.2,-0.07,1.186,,65.03,HBH,-1.30267,0.213352,0.00123327,1.00332 kka2_1:8_A79W,kka2_1:8_79,Kka2,kka2_1:8,P00552,1.00332,NO,79,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.368,-5.595,3.227,,0.563,.,B,0.46,-0.43,,,71.59,HHH,-1.752,0.100394,0.00664821,1.00332 kka2_1:8_A79W,kka2_1:8_79,Kka2,kka2_1:8,P00552,1.00332,NO,79,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.368,-5.595,3.227,,0.563,.,B,0.46,-0.43,,,71.59,HHH,-1.752,0.100394,0.00664821,1.00332 beta-lactamase_39_L284F,beta-lactamase_39_284,TEM-1,beta-lactamase_39,P62593,1.00333,NO,284,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.0495842,0.0686156,1.00333 beta-lactamase_625_P60M,beta-lactamase_625_60,TEM-1,beta-lactamase_625,P62593,1.00333,NO,60,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-2.469,-4.701,2.232,,0.256,T,A,0.52,-0.56,3.653,,77.62,BOA,-1.97633,0.213352,0.00521318,1.00333 kka2_1:8_D23Y,kka2_1:8_23,Kka2,kka2_1:8,P00552,1.00333,NO,23,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.459,-4.392,1.933,,0.695,E,B,0.75,-0.65,,,65.53,HAH,-1.94033,0.100394,0.007195,1.00333 kka2_1:8_D23Y,kka2_1:8_23,Kka2,kka2_1:8,P00552,1.00333,NO,23,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.459,-4.392,1.933,,0.695,E,B,0.75,-0.65,,,65.53,HAH,-1.94033,0.100394,0.007195,1.00333 Pab1_A185T,Pab1_185,Pab1,Pab1,P04147,1.00333,NO,185,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.702,-3.16,1.458,,,,,,,1.756,,63.26,AHH,-1.66167,0.175299,0.00144499,1.00333 Pab1_E161G,Pab1_161,Pab1,Pab1,P04147,1.00333,NO,161,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.474,-3.117,1.643,,0.663,T,a,,1.34,,,,AAP,-1.59067,0.175299,0.00276141,1.00333 Pab1_E175Q,Pab1_175,Pab1,Pab1,P04147,1.00333,NO,175,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.055,-3.657,1.602,,,,,,,,,,AAA,-1.82667,0.175299,0.00203137,1.00333 beta-lactamase_39_R273W,beta-lactamase_39_273,TEM-1,beta-lactamase_39,P62593,1.00334,NO,273,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.314,-5.456,3.142,,0.564,H,A,1.2,1.57,2.163,,73.78,ABP,-1.841,0.0495842,0.0077952,1.00334 beta-lactamase_N173S,beta-lactamase_173,TEM-1,beta-lactamase,P62593,1.00334,NO,173,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-2.663,-3.203,0.54,7.02497,1.044,T,l,0.09,1.25,1.88,,77.62,OPA,-1.46633,0.221079,0.0033769,1.00334 gb1_K230R,gb1_230,gb1,gb1,P06654,1.00334,NO,230,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.701,-3.196,1.495,,,,,,,0.166,,11.83,HBH,-1.52867,0.177985,0.00331703,1.00334 Pab1_N192C,Pab1_192,Pab1,Pab1,P04147,1.00334,NO,192,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-1.079,-4.904,3.825,,0.619,T,l,,2.28,,,,HPO,-1.231,0.175299,0.000273498,1.00334 PSD95pdz3_D366F,PSD95pdz3_366,PSD95pdz3,PSD95pdz3,P31016,1.00334,NO,366,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.264,-3.974,2.71,5.55684,,,,,20.2375,,,,HAH,-1.401,0.0758425,0.000481272,1.00334 beta-lactamase_156_A182S,beta-lactamase_156_182,TEM-1,beta-lactamase_156,P62593,1.00335,NO,182,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.777,-2.825,1.048,,0.136,H,A,0.46,-0.66,16.784,16.784,93.01,OHH,-1.27367,0.111618,0.00559099,1.00335 beta-lactamase_156_N173K,beta-lactamase_156_173,TEM-1,beta-lactamase_156,P62593,1.00335,NO,173,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-2.663,-2.711,0.048,,1.044,T,l,0.61,1.25,3.718,,77.62,OPA,-1.46633,0.111618,0.0033769,1.00335 beta-lactamase_39_S266Q,beta-lactamase_39_266,TEM-1,beta-lactamase_39,P62593,1.00335,NO,266,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.0495842,0.0140785,1.00335 beta-lactamase_39_V29Q,beta-lactamase_39_29,TEM-1,beta-lactamase_39,P62593,1.00335,NO,29,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-2.856,-2.926,0.07,,0.733,H,A,0.44,-0.78,1.287,,93.01,HHB,-2.24733,0.0495842,0.00318969,1.00335 beta-lactamase_625_A225P,beta-lactamase_625_225,TEM-1,beta-lactamase_625,P62593,1.00335,NO,225,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.845,-3.112,1.267,,1,T,B,0.46,-0.38,9.874,9.874,74.48,OHO,-1.39967,0.213352,0.00465057,1.00335 beta-lactamase_156_L160Q,beta-lactamase_156_160,TEM-1,beta-lactamase_156,P62593,1.00337,NO,160,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.977,-4.199,3.222,,0.022,,B,0.55,-0.6,1.095,,44.41,BHA,-0.936,0.111618,0.00193775,1.00337 beta-lactamase_156_T186S,beta-lactamase_156_186,TEM-1,beta-lactamase_156,P62593,1.00337,NO,186,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.522,-2.471,-0.051,,0.396,H,A,0.22,-0.28,16.606,16.606,77.62,HPP,-1.77633,0.111618,0.00485034,1.00337 beta-lactamase_625_R159W,beta-lactamase_625_159,TEM-1,beta-lactamase_625,P62593,1.00337,NO,159,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-0.94,-5.32,4.38,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.213352,0.00108472,1.00337 beta-lactamase_156_I277M,beta-lactamase_156_277,TEM-1,beta-lactamase_156,P62593,1.00338,NO,277,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.111618,0.0169305,1.00338 beta-lactamase_39_A123H,beta-lactamase_39_123,TEM-1,beta-lactamase_39,P62593,1.00338,NO,123,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.834,-4.729,3.895,,0.039,H,A,0.46,-0.72,0.705,,41.26,PHH,-1.47367,0.0495842,0.0010157,1.00338 beta-lactamase_39_R257V,beta-lactamase_39_257,TEM-1,beta-lactamase_39,P62593,1.00338,NO,257,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.533,-4.11,2.577,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.0495842,0.00756629,1.00338 beta-lactamase_39_G253V,beta-lactamase_39_253,TEM-1,beta-lactamase_39,P62593,1.00339,NO,253,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.0495842,0.00786358,1.00339 beta-lactamase_39_R275T,beta-lactamase_39_275,TEM-1,beta-lactamase_39,P62593,1.00339,NO,275,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.0495842,0.0141984,1.00339 beta-lactamase_625_M153Q,beta-lactamase_625_153,TEM-1,beta-lactamase_625,P62593,1.00339,NO,153,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-3.193,-4.202,1.009,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.213352,0.00509109,1.00339 beta-lactamase_625_T186W,beta-lactamase_625_186,TEM-1,beta-lactamase_625,P62593,1.00339,NO,186,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.522,-5.446,2.924,,0.396,H,A,0.22,-0.28,0.515,,77.62,HPP,-1.77633,0.213352,0.00485034,1.00339 beta-lactamase_156_Q97V,beta-lactamase_156_97,TEM-1,beta-lactamase_156,P62593,1.0034,NO,97,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.072,-3.633,1.561,,0.823,G,A,0.64,2.42,4.457,,77.62,PPP,-2.43833,0.111618,0.0045116,1.0034 beta-lactamase_156_R92M,beta-lactamase_156_92,TEM-1,beta-lactamase_156,P62593,1.0034,NO,92,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.718,-3.339,1.621,,0.479,E,B,1.2,1.36,19.112,19.112,65.38,BBH,-1.50367,0.111618,0.00429626,1.0034 beta-lactamase_2500_F70M,beta-lactamase_2500_70,TEM-1,beta-lactamase_2500,P62593,1.0034,NO,70,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.169,-3.002,1.833,,,H,A,0.58,-1.34,1.918,,63.99,PHB,-0.980667,0.361275,0.00193499,1.0034 beta-lactamase_2500_E169A,beta-lactamase_2500_169,TEM-1,beta-lactamase_2500,P62593,1.00341,NO,169,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.23,-2.486,1.256,,0.337,,A,1.04,1,1.806,,73.08,PAH,-1.16533,0.361275,0.00400994,1.00341 PSD95pdz3_A343F,PSD95pdz3_343,PSD95pdz3,PSD95pdz3,P31016,1.00342,NO,343,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.307,-3.749,2.442,5.585,,,,,14.728,,,,HHO,-1.22067,0.0758425,0.000798084,1.00342 beta-lactamase_156_E175K,beta-lactamase_156_175,TEM-1,beta-lactamase_156,P62593,1.00343,NO,175,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.336,-2.673,0.337,,0.551,,A,1.04,1.05,2.334,,77.62,AAB,-1.31233,0.111618,0.00482205,1.00343 beta-lactamase_156_K53L,beta-lactamase_156_53,TEM-1,beta-lactamase_156,P62593,1.00343,NO,53,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-2.313,-2.678,0.365,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.111618,0.00383383,1.00343 beta-lactamase_39_L79Y,beta-lactamase_39_79,TEM-1,beta-lactamase_39,P62593,1.00343,NO,79,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.842,-3.963,3.121,,0.007,H,A,0.55,-0.16,0.823,,50.35,HHP,-1.44333,0.0495842,0.000947397,1.00343 hsp90_A587A,hsp90_587,hsp90,hsp90,P02829,1.00343,NO,587,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.456,-2.456,,4.91216,0.049,H,A,0.55,-0.02,,,,PHP,-2.757,0.368192,0.000222939,1.00343 beta-lactamase_2500_S96H,beta-lactamase_2500_96,TEM-1,beta-lactamase_2500,P62593,1.00344,NO,96,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.27,-3.418,1.148,,0.368,,b,0.27,0.39,32.348,32.348,73.78,HPP,-2.019,0.361275,0.00551835,1.00344 beta-lactamase_39_P172M,beta-lactamase_39_172,TEM-1,beta-lactamase_39,P62593,1.00344,NO,172,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.998,-4.616,3.618,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.0495842,0.00312594,1.00344 beta-lactamase_2500_A282N,beta-lactamase_2500_282,TEM-1,beta-lactamase_2500,P62593,1.00345,NO,282,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.361275,0.0449821,1.00345 beta-lactamase_2500_Q267R,beta-lactamase_2500_267,TEM-1,beta-lactamase_2500,P62593,1.00345,NO,267,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.361275,0.0102128,1.00345 beta-lactamase_39_G226H,beta-lactamase_39_226,TEM-1,beta-lactamase_39,P62593,1.00345,NO,226,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.461,-4.656,3.195,,0.701,T,l,0.29,-0.25,23.034,23.034,74.48,HOH,-1.42933,0.0495842,0.00665294,1.00345 beta-lactamase_39_L49R,beta-lactamase_39_49,TEM-1,beta-lactamase_39,P62593,1.00345,NO,49,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.897,-3.032,1.135,,0.131,T,A,0.55,0.04,13.838,13.838,64.69,AHP,-1.99233,0.0495842,0.00401477,1.00345 kka2_1:8_P179L,kka2_1:8_179,Kka2,kka2_1:8,P00552,1.00345,NO,179,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.974,-2.273,1.299,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.100394,0.00298346,1.00345 kka2_1:8_P179L,kka2_1:8_179,Kka2,kka2_1:8,P00552,1.00345,NO,179,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.974,-2.273,1.299,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.100394,0.00298346,1.00345 beta-lactamase_39_T187M,beta-lactamase_39_187,TEM-1,beta-lactamase_39,P62593,1.00346,NO,187,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.401,-4.516,3.115,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.0495842,0.00491782,1.00346 beta-lactamase_625_A211L,beta-lactamase_625_211,TEM-1,beta-lactamase_625,P62593,1.00346,NO,211,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.896,-3.595,1.699,,0.369,T,A,0.46,-0.69,2.061,,77.62,AHA,-1.94633,0.213352,0.00648183,1.00346 beta-lactamase_625_L55G,beta-lactamase_625_55,TEM-1,beta-lactamase_625,P62593,1.00346,NO,55,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.86,-3.665,1.805,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.213352,0.00403741,1.00346 beta-lactamase_39_A200G,beta-lactamase_39_200,TEM-1,beta-lactamase_39,P62593,1.00347,NO,200,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.878,-2.76,0.882,,0.757,H,A,0.46,-0.19,1.54,,77.62,HHP,-2.001,0.0495842,0.0060056,1.00347 beta-lactamase_625_P181V,beta-lactamase_625_181,TEM-1,beta-lactamase_625,P62593,1.00347,NO,181,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.813,-3.492,2.679,,,H,A,0.52,-1.14,1.797,,61.54,HOH,-1.795,0.213352,0.000703122,1.00347 beta-lactamase_625_P65A,beta-lactamase_625_65,TEM-1,beta-lactamase_625,P62593,1.00347,NO,65,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.894,-3.096,2.202,,0.098,E,B,0.52,-0.62,0.3,,40.56,HOH,-1.03233,0.213352,0.00152776,1.00347 beta-lactamase_2500_I171W,beta-lactamase_2500_171,TEM-1,beta-lactamase_2500,P62593,1.00348,NO,171,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-2.431,-5.376,2.945,,0.361,,B,0.48,0.53,1.66,,77.62,HHO,-1.55533,0.361275,0.00623355,1.00348 beta-lactamase_39_T107L,beta-lactamase_39_107,TEM-1,beta-lactamase_39,P62593,1.00348,NO,107,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.117,-3.237,2.12,,,G,A,0.22,-0.06,2.686,,67.83,HPA,-1.265,0.0495842,0.00239347,1.00348 beta-lactamase_39_W163D,beta-lactamase_39_163,TEM-1,beta-lactamase_39,P62593,1.00348,NO,163,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-1.843,-3.903,2.06,,0.467,,B,0.47,-0.5,15.095,15.095,63.99,BHA,-1.269,0.0495842,0.00418955,1.00348 beta-lactamase_625_A182G,beta-lactamase_625_182,TEM-1,beta-lactamase_625,P62593,1.00348,NO,182,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.777,-3.408,1.631,,0.136,H,A,0.46,-0.66,16.784,16.784,93.01,OHH,-1.27367,0.213352,0.00559099,1.00348 beta-lactamase_625_I244C,beta-lactamase_625_244,TEM-1,beta-lactamase_625,P62593,1.00348,NO,244,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.555,-4.712,3.157,,,E,B,0.48,-0.84,2.061,,77.62,OHH,-1.385,0.213352,0.00605379,1.00348 beta-lactamase_625_P217Q,beta-lactamase_625_217,TEM-1,beta-lactamase_625,P62593,1.00348,NO,217,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-2.062,-3.933,1.871,,0.496,I,A,0.52,-0.33,1.087,,74.48,OOH,-1.64333,0.213352,0.00463211,1.00348 beta-lactamase_625_S122G,beta-lactamase_625_122,TEM-1,beta-lactamase_625,P62593,1.00348,NO,122,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.406,-3.475,1.069,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.213352,0.00497825,1.00348 beta-lactamase_156_I140M,beta-lactamase_156_140,TEM-1,beta-lactamase_156,P62593,1.00349,NO,140,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.733,-4.137,2.404,,0.128,H,A,0.48,0.41,1.16,,73.08,PHO,-1.48733,0.111618,0.00597777,1.00349 beta-lactamase_156_L192V,beta-lactamase_156_192,TEM-1,beta-lactamase_156,P62593,1.00349,NO,192,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.254,-1.986,0.732,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.111618,0.00558728,1.00349 beta-lactamase_156_T116F,beta-lactamase_156_116,TEM-1,beta-lactamase_156,P62593,1.00349,NO,116,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.28,-4.243,2.963,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.111618,0.00336175,1.00349 beta-lactamase_39_I229Q,beta-lactamase_39_229,TEM-1,beta-lactamase_39,P62593,1.00349,NO,229,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.267,-4.304,3.037,,0.083,E,B,0.48,-0.76,1.114,,50,HHH,-1.58767,0.0495842,0.00477249,1.00349 beta-lactamase_39_T193F,beta-lactamase_39_193,TEM-1,beta-lactamase_39,P62593,1.00349,NO,193,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.914,-2.368,0.454,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.0495842,0.00482669,1.00349 beta-lactamase_625_S201T,beta-lactamase_625_201,TEM-1,beta-lactamase_625,P62593,1.00349,NO,201,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.183,-3.198,2.015,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.213352,0.00198815,1.00349 beta-lactamase_625_Y103M,beta-lactamase_625_103,TEM-1,beta-lactamase_625,P62593,1.00349,NO,103,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-1.33,-4.627,3.297,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.213352,0.00443048,1.00349 beta-lactamase_0_L73S,beta-lactamase_0_73,TEM-1,beta-lactamase_0,P62593,1.0035,NO,73,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.507,-3.664,2.157,,,H,A,0.55,-0.64,0.877,,67.83,HHH,-1.487,0.0500837,0.00488983,1.0035 beta-lactamase_39_R275G,beta-lactamase_39_275,TEM-1,beta-lactamase_39,P62593,1.0035,NO,275,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.0495842,0.0141984,1.0035 beta-lactamase_625_P25C,beta-lactamase_625_25,TEM-1,beta-lactamase_625,P62593,1.0035,NO,25,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.526,-5.046,3.52,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.213352,0.00347571,1.0035 beta-lactamase_L49L,beta-lactamase_49,TEM-1,beta-lactamase,P62593,1.0035,NO,49,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.897,-1.897,,5.86005,0.131,T,A,1.3,0.04,3.112,,64.69,AHP,-1.99233,0.221079,0.00401477,1.0035 gb1_N234A,gb1_234,gb1,gb1,P06654,1.0035,NO,234,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-2.055,-2.977,0.922,,,,,,,1.235,,45.54,HPO,-2.05067,0.177985,0.00242189,1.0035 gb1_T279Q,gb1_279,gb1,gb1,P06654,1.0035,NO,279,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.32,-3.849,2.529,,,,,,,0.529,,35.71,HPH,-1.50067,0.177985,0.00421454,1.0035 beta-lactamase_156_D36E,beta-lactamase_156_36,TEM-1,beta-lactamase_156,P62593,1.00351,NO,36,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.732,-2.66,-0.072,,0.555,H,A,0.75,1.17,14.871,14.871,77.62,AAP,-1.91167,0.111618,0.00476483,1.00351 beta-lactamase_39_A246V,beta-lactamase_39_246,TEM-1,beta-lactamase_39,P62593,1.00351,NO,246,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.121,-1.76,-0.361,,0.01,E,B,0.46,-1.01,1.331,,73.78,HHH,-1.55633,0.0495842,0.00569458,1.00351 beta-lactamase_39_H151E,beta-lactamase_39_151,TEM-1,beta-lactamase_39,P62593,1.00351,NO,151,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-2.96,-3.258,0.298,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.0495842,0.00216946,1.00351 PSD95pdz3_T385S,PSD95pdz3_385,PSD95pdz3,PSD95pdz3,P31016,1.00351,NO,385,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.533,-1.86,0.327,5.57157,,,,,23.6871,4.527,,87.71,PPH,-1.56567,0.0758425,0.000545119,1.00351 beta-lactamase_0_K232W,beta-lactamase_0_232,TEM-1,beta-lactamase_0,P62593,1.00352,NO,232,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.012,-5.365,4.353,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.0500837,0.00313441,1.00352 beta-lactamase_156_W163G,beta-lactamase_156_163,TEM-1,beta-lactamase_156,P62593,1.00352,NO,163,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-1.843,-2.648,0.805,,0.467,,B,0.47,-0.5,15.095,15.095,63.99,BHA,-1.269,0.111618,0.00418955,1.00352 beta-lactamase_2500_Q37K,beta-lactamase_2500_37,TEM-1,beta-lactamase_2500,P62593,1.00352,NO,37,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.134,-2.595,0.461,,0.613,H,A,0.64,1.98,1.318,,73.08,APH,-2.06967,0.361275,0.00425833,1.00352 beta-lactamase_39_E145A,beta-lactamase_39_145,TEM-1,beta-lactamase_39,P62593,1.00352,NO,145,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.357,-1.901,-0.456,,0.545,H,A,1.04,0.79,1.199,,77.62,BAH,-2.069,0.0495842,0.00553285,1.00352 beta-lactamase_156_R59S,beta-lactamase_156_59,TEM-1,beta-lactamase_156,P62593,1.00353,NO,59,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.345,-2.706,1.361,,0.329,S,L,1.2,-0.09,2.995,,73.08,HBO,-2.24267,0.111618,0.00318082,1.00353 beta-lactamase_39_D174N,beta-lactamase_39_174,TEM-1,beta-lactamase_39,P62593,1.00353,NO,174,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.738,-3.223,2.485,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.0495842,0.00125633,1.00353 beta-lactamase_39_Q88K,beta-lactamase_39_88,TEM-1,beta-lactamase_39,P62593,1.00353,NO,88,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.086,-2.839,0.753,,0.807,,B,0.64,2.03,11.108,11.108,77.62,APH,-1.53433,0.0495842,0.00504167,1.00353 beta-lactamase_156_E238K,beta-lactamase_156_238,TEM-1,beta-lactamase_156,P62593,1.00354,NO,238,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.111618,0.00743256,1.00354 beta-lactamase_156_N152K,beta-lactamase_156_152,TEM-1,beta-lactamase_156,P62593,1.00355,NO,152,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-2.757,-2.892,0.135,,0.863,H,A,0.61,0.92,4.038,,77.62,BPH,-2.97,0.111618,0.00471429,1.00355 kka2_1:4_A13E,kka2_1:4_13,Kka2,kka2_1:4,P00552,1.00355,NO,13,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.248,-2.832,0.584,,0.689,G,A,0.46,0.99,,,92.05,OHH,-1.646,0.168804,0.00784241,1.00355 Pab1_N132A,Pab1_132,Pab1,Pab1,P04147,1.00355,NO,132,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-1.079,-3.12,2.041,,0.412,S,l,,0.9,,,,BPH,-1.067,0.175299,0.000347671,1.00355 beta-lactamase_156_L137N,beta-lactamase_156_137,TEM-1,beta-lactamase_156,P62593,1.00356,NO,137,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.03,-4.152,3.122,,,H,A,0.55,-0.38,0.674,,42.31,HHP,-1.58933,0.111618,0.00278599,1.00356 beta-lactamase_625_D36H,beta-lactamase_625_36,TEM-1,beta-lactamase_625,P62593,1.00356,NO,36,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.732,-3.09,0.358,,0.555,H,A,0.75,1.17,2.26,,77.62,AAP,-1.91167,0.213352,0.00476483,1.00356 beta-lactamase_625_H151V,beta-lactamase_625_151,TEM-1,beta-lactamase_625,P62593,1.00356,NO,151,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-2.96,-3.785,0.825,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.213352,0.00216946,1.00356 beta-lactamase_156_D36T,beta-lactamase_156_36,TEM-1,beta-lactamase_156,P62593,1.00357,NO,36,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.732,-2.57,-0.162,,0.555,H,A,0.75,1.17,14.871,14.871,77.62,AAP,-1.91167,0.111618,0.00476483,1.00357 beta-lactamase_39_N274S,beta-lactamase_39_274,TEM-1,beta-lactamase_39,P62593,1.00357,NO,274,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.0495842,0.0110418,1.00357 beta-lactamase_39_S122E,beta-lactamase_39_122,TEM-1,beta-lactamase_39,P62593,1.00357,NO,122,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.406,-2.103,-0.303,,0.352,H,A,0.27,-0.54,2.004,,77.62,OPH,-1.39767,0.0495842,0.00497825,1.00357 beta-lactamase_39_V29P,beta-lactamase_39_29,TEM-1,beta-lactamase_39,P62593,1.00357,NO,29,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-2.856,-3.853,0.997,,0.733,H,A,0.44,-0.78,1.287,,93.01,HHB,-2.24733,0.0495842,0.00318969,1.00357 beta-lactamase_39_P181V,beta-lactamase_39_181,TEM-1,beta-lactamase_39,P62593,1.00358,NO,181,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.813,-3.492,2.679,,,H,A,0.52,-1.14,1.946,,61.54,HOH,-1.795,0.0495842,0.000703122,1.00358 beta-lactamase_E169E,beta-lactamase_169,TEM-1,beta-lactamase,P62593,1.00358,NO,169,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.23,-1.23,,5.78896,0.337,,A,0.52,1,1.806,,73.08,PAH,-1.16533,0.221079,0.00400994,1.00358 kka2_1:2_G10V,kka2_1:2_10,Kka2,kka2_1:2,P00552,1.00358,NO,10,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.921,-3.683,1.762,,,,,,,2.192,,71.59,HOP,-2.10733,0.295029,0.00289233,1.00358 beta-lactamase_2500_E102S,beta-lactamase_2500_102,TEM-1,beta-lactamase_2500,P62593,1.00359,NO,102,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.118,-2.129,0.011,,0.722,S,B,1.04,1.82,1.336,,73.08,HAH,-1.581,0.361275,0.00486633,1.00359 beta-lactamase_39_K32N,beta-lactamase_39_32,TEM-1,beta-lactamase_39,P62593,1.00359,NO,32,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.984,-2.965,0.981,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.0495842,0.00401283,1.00359 hsp90_G584G,hsp90_584,hsp90,hsp90,P02829,1.00359,NO,584,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-2.511,-2.511,,5.20094,0.414,S,b,0.84,0.33,,,,HOH,-3.32733,0.368192,0.000222939,1.00359 beta-lactamase_156_K30S,beta-lactamase_156_30,TEM-1,beta-lactamase_156,P62593,1.0036,NO,30,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-2.307,-3.277,0.97,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.111618,0.00448593,1.0036 beta-lactamase_156_L196W,beta-lactamase_156_196,TEM-1,beta-lactamase_156,P62593,1.0036,NO,196,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-2.478,-5.492,3.014,,0.518,S,A,0.55,1.35,7.897,,77.62,AHH,-1.839,0.111618,0.00512144,1.0036 beta-lactamase_156_T69H,beta-lactamase_156_69,TEM-1,beta-lactamase_156,P62593,1.0036,NO,69,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-0.973,-4.716,3.743,,,G,A,0.22,-1.24,4.194,,93.01,PPH,-1.01833,0.111618,0.00127498,1.0036 beta-lactamase_39_A185S,beta-lactamase_39_185,TEM-1,beta-lactamase_39,P62593,1.00361,NO,185,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.406,-3.291,1.885,,,H,A,0.46,-1.02,2.68,,65.03,HHP,-1.84033,0.0495842,0.00467449,1.00361 beta-lactamase_156_A200G,beta-lactamase_156_200,TEM-1,beta-lactamase_156,P62593,1.00362,NO,200,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.878,-2.76,0.882,,0.757,H,A,0.46,-0.19,16.368,16.368,77.62,HHP,-2.001,0.111618,0.0060056,1.00362 Pab1_N162K,Pab1_162,Pab1,Pab1,P04147,1.00362,NO,162,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-2.313,-3.493,1.18,,0.681,T,A,,1.12,,,,APO,-1.532,0.175299,0.0030719,1.00362 beta-lactamase_L111T,beta-lactamase_111,TEM-1,beta-lactamase,P62593,1.00363,NO,111,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.76,-2.765,1.005,5.8705,0.328,T,A,0.84,0.93,3.836,,64.34,BHP,-1.884,0.221079,0.00480671,1.00363 beta-lactamase_S281Q,beta-lactamase_281,TEM-1,beta-lactamase,P62593,1.00363,NO,281,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.247,-4.061,1.814,4.73591,0.128,H,A,0.25,-0.26,2.144,,77.62,HPH,-1.847,0.221079,0.0406482,1.00363 beta-lactamase_156_Q267L,beta-lactamase_156_267,TEM-1,beta-lactamase_156,P62593,1.00364,NO,267,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.111618,0.0102128,1.00364 beta-lactamase_39_G90C,beta-lactamase_39_90,TEM-1,beta-lactamase_39,P62593,1.00364,NO,90,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-2.091,-5.167,3.076,,0.598,T,A,0.29,0.32,30.794,30.794,77.62,HOB,-1.52633,0.0495842,0.00490273,1.00364 kka2_1:2_P249H,kka2_1:2_249,Kka2,kka2_1:2,P00552,1.00364,NO,249,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.867,-4.971,3.104,,0.406,.,B,0.52,-0.01,0.76,,92.05,HOA,-1.66867,0.295029,0.011045,1.00364 kka2_1:4_Q163T,kka2_1:4_163,Kka2,kka2_1:4,P00552,1.00364,NO,163,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.162,-2.589,0.427,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.168804,0.00719507,1.00364 beta-lactamase_625_M127T,beta-lactamase_625_127,TEM-1,beta-lactamase_625,P62593,1.00365,NO,127,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-2.251,-2.593,0.342,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.213352,0.00437927,1.00365 beta-lactamase_S221S,beta-lactamase_221,TEM-1,beta-lactamase,P62593,1.00365,NO,221,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.754,-1.754,,5.77407,0.624,H,A,0.74,-0.2,0.383,,74.48,BPH,-1.59967,0.221079,0.0046094,1.00365 beta-lactamase_156_N173P,beta-lactamase_156_173,TEM-1,beta-lactamase_156,P62593,1.00366,NO,173,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-2.663,-3.891,1.228,,1.044,T,l,0.61,1.25,3.718,,77.62,OPA,-1.46633,0.111618,0.0033769,1.00366 beta-lactamase_156_T269D,beta-lactamase_156_269,TEM-1,beta-lactamase_156,P62593,1.00366,NO,269,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.156,-3.518,1.362,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.111618,0.00950944,1.00366 beta-lactamase_39_L150S,beta-lactamase_39_150,TEM-1,beta-lactamase_39,P62593,1.00366,NO,150,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.326,-3.477,2.151,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.0495842,0.00463171,1.00366 beta-lactamase_39_V82A,beta-lactamase_39_82,TEM-1,beta-lactamase_39,P62593,1.00366,NO,82,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.325,-2.13,0.805,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.0495842,0.00397046,1.00366 beta-lactamase_625_R81W,beta-lactamase_625_81,TEM-1,beta-lactamase_625,P62593,1.00366,NO,81,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.466,-5.415,3.949,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.213352,0.00499763,1.00366 beta-lactamase_E145R,beta-lactamase_145,TEM-1,beta-lactamase,P62593,1.00366,NO,145,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.357,-2.676,0.319,5.38104,0.545,H,A,0.52,0.79,2.124,,77.62,BAH,-2.069,0.221079,0.00553285,1.00366 gb1_T270F,gb1_270,gb1,gb1,P06654,1.00366,NO,270,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-3.15,-2.393,-0.757,,,,,,,1.326,,45.54,HPH,-1.843,0.177985,0.00223707,1.00366 beta-lactamase_156_T264R,beta-lactamase_156_264,TEM-1,beta-lactamase_156,P62593,1.00367,NO,264,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.111618,0.0119399,1.00367 beta-lactamase_2500_A222R,beta-lactamase_2500_222,TEM-1,beta-lactamase_2500,P62593,1.00367,NO,222,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.103,-4.005,1.902,,0.233,H,A,0.46,-0.25,0.379,,77.62,PHH,-1.63733,0.361275,0.00466094,1.00367 beta-lactamase_2500_L199C,beta-lactamase_2500_199,TEM-1,beta-lactamase_2500,P62593,1.00367,NO,199,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-2.942,-5.078,2.136,,0.832,H,A,0.55,0.42,15.504,15.504,77.62,PHH,-2.32933,0.361275,0.0048649,1.00367 beta-lactamase_39_R59L,beta-lactamase_39_59,TEM-1,beta-lactamase_39,P62593,1.00367,NO,59,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.345,-3.484,2.139,,0.329,S,L,1.2,-0.09,1.806,,73.08,HBO,-2.24267,0.0495842,0.00318082,1.00367 PSD95pdz3_Y392L,PSD95pdz3_392,PSD95pdz3,PSD95pdz3,P31016,1.00367,NO,392,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-1.437,-2.815,1.378,5.20337,,,,,11.725,,,,PHB,-1.51733,0.0758425,0.000935211,1.00367 beta-lactamase_156_R63V,beta-lactamase_156_63,TEM-1,beta-lactamase_156,P62593,1.00368,NO,63,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-0.943,-3.626,2.683,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.111618,0.00126938,1.00368 beta-lactamase_156_R92N,beta-lactamase_156_92,TEM-1,beta-lactamase_156,P62593,1.00368,NO,92,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.718,-2.988,1.27,,0.479,E,B,1.2,1.36,19.112,19.112,65.38,BBH,-1.50367,0.111618,0.00429626,1.00368 beta-lactamase_2500_H110K,beta-lactamase_2500_110,TEM-1,beta-lactamase_2500,P62593,1.00368,NO,110,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-1.706,-2.755,1.049,,0.341,G,a,0.17,1.08,31.31,31.31,64.69,BBH,-1.73333,0.361275,0.00441499,1.00368 beta-lactamase_2500_T112L,beta-lactamase_2500_112,TEM-1,beta-lactamase_2500,P62593,1.00368,NO,112,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.186,-3.575,1.389,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.361275,0.00531334,1.00368 beta-lactamase_625_A247L,beta-lactamase_625_247,TEM-1,beta-lactamase_625,P62593,1.00368,NO,247,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.48,-2.56,1.08,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.213352,0.00611275,1.00368 beta-lactamase_P172P,beta-lactamase_172,TEM-1,beta-lactamase,P62593,1.00368,NO,172,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.998,-0.998,,5.98941,0.639,T,b,1.1,0.24,2.087,,74.48,HOP,-2.03067,0.221079,0.00312594,1.00368 Pab1_D160T,Pab1_160,Pab1,Pab1,P04147,1.00368,NO,160,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.985,-3.239,2.254,,0.396,B,B,,1.12,,,,PAA,-1.30133,0.175299,0.000311977,1.00368 beta-lactamase_156_T186F,beta-lactamase_156_186,TEM-1,beta-lactamase_156,P62593,1.00369,NO,186,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.522,-4.342,1.82,,0.396,H,A,0.22,-0.28,16.606,16.606,77.62,HPP,-1.77633,0.111618,0.00485034,1.00369 beta-lactamase_2500_Q267M,beta-lactamase_2500_267,TEM-1,beta-lactamase_2500,P62593,1.00369,NO,267,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.361275,0.0102128,1.00369 beta-lactamase_39_L38Y,beta-lactamase_39_38,TEM-1,beta-lactamase_39,P62593,1.00369,NO,38,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.343,-2.956,1.613,,0.088,H,A,0.55,0.2,17.089,17.089,64.34,PHO,-1.78033,0.0495842,0.00373244,1.00369 beta-lactamase_39_P105V,beta-lactamase_39_105,TEM-1,beta-lactamase_39,P62593,1.00369,NO,105,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.813,-3.554,2.741,,0.226,T,A,0.52,0.8,1.222,,63.29,POH,-1.01533,0.0495842,0.0011981,1.00369 beta-lactamase_625_R239L,beta-lactamase_625_239,TEM-1,beta-lactamase_625,P62593,1.0037,NO,239,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.213352,0.00213852,1.0037 beta-lactamase_156_E166S,beta-lactamase_156_166,TEM-1,beta-lactamase_156,P62593,1.00371,NO,166,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.756,-2.582,0.826,,0.508,G,A,1.04,1.05,2.393,,73.08,OAH,-1.42233,0.111618,0.00512989,1.00371 beta-lactamase_156_K53A,beta-lactamase_156_53,TEM-1,beta-lactamase_156,P62593,1.00371,NO,53,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-2.313,-2.735,0.422,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.111618,0.00383383,1.00371 beta-lactamase_156_P25K,beta-lactamase_156_25,TEM-1,beta-lactamase_156,P62593,1.00371,NO,25,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.526,-3.426,1.9,,0.624,H,A,0.52,0.14,1.079,,73.08,BOA,-2.15367,0.111618,0.00347571,1.00371 beta-lactamase_625_E108L,beta-lactamase_625_108,TEM-1,beta-lactamase_625,P62593,1.00371,NO,108,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.46,-3.653,2.193,,0.572,G,A,1.04,1.87,20.151,20.151,72.73,PAB,-1.437,0.213352,0.00413372,1.00371 beta-lactamase_2500_A200G,beta-lactamase_2500_200,TEM-1,beta-lactamase_2500,P62593,1.00372,NO,200,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.878,-2.76,0.882,,0.757,H,A,0.46,-0.19,0.436,,77.62,HHP,-2.001,0.361275,0.0060056,1.00372 beta-lactamase_2500_S80W,beta-lactamase_2500_80,TEM-1,beta-lactamase_2500,P62593,1.00372,NO,80,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.029,-5.529,3.5,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.361275,0.00565569,1.00372 beta-lactamase_39_A183G,beta-lactamase_39_183,TEM-1,beta-lactamase_39,P62593,1.00372,NO,183,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.231,-3.077,1.846,,0.155,H,A,0.46,-0.91,1.237,,77.62,HHH,-1.53367,0.0495842,0.00296631,1.00372 beta-lactamase_625_A183E,beta-lactamase_625_183,TEM-1,beta-lactamase_625,P62593,1.00372,NO,183,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.231,-3.42,2.189,,0.155,H,A,0.46,-0.91,23.859,23.859,77.62,HHH,-1.53367,0.213352,0.00296631,1.00372 beta-lactamase_625_D271E,beta-lactamase_625_271,TEM-1,beta-lactamase_625,P62593,1.00372,NO,271,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.213352,0.00752082,1.00372 beta-lactamase_625_G234A,beta-lactamase_625_234,TEM-1,beta-lactamase_625,P62593,1.00372,NO,234,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.62,-2.853,2.233,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.213352,0.000889577,1.00372 kka2_1:4_W15G,kka2_1:4_15,Kka2,kka2_1:4,P00552,1.00372,NO,15,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-1.392,-3.656,2.264,,0.01,G,A,0.47,0.15,0.943,,52.27,HHH,-2.10533,0.168804,0.00585505,1.00372 beta-lactamase_2500_G226D,beta-lactamase_2500_226,TEM-1,beta-lactamase_2500,P62593,1.00373,NO,226,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.461,-1.914,0.453,,0.701,T,l,0.29,-0.25,5.086,,74.48,HOH,-1.42933,0.361275,0.00665294,1.00373 beta-lactamase_625_D271S,beta-lactamase_625_271,TEM-1,beta-lactamase_625,P62593,1.00373,NO,271,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.213352,0.00752082,1.00373 beta-lactamase_625_V82A,beta-lactamase_625_82,TEM-1,beta-lactamase_625,P62593,1.00373,NO,82,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.325,-2.13,0.805,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.213352,0.00397046,1.00373 PSD95pdz3_N369H,PSD95pdz3_369,PSD95pdz3,PSD95pdz3,P31016,1.00373,NO,369,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-1.572,-3.939,2.367,5.91569,,,,,24.1262,0.44,,87.71,BPH,-1.487,0.0758425,0.000608412,1.00373 beta-lactamase_39_Q204I,beta-lactamase_39_204,TEM-1,beta-lactamase_39,P62593,1.00374,NO,204,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-1.382,-3.968,2.586,,0.204,H,A,0.64,0.09,0.489,,66.08,PPH,-1.49067,0.0495842,0.00364106,1.00374 beta-lactamase_A222E,beta-lactamase_222,TEM-1,beta-lactamase,P62593,1.00374,NO,222,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.103,-3.646,1.543,5.2262,0.233,H,A,0.47,-0.25,0.379,,77.62,PHH,-1.63733,0.221079,0.00466094,1.00374 beta-lactamase_156_A133G,beta-lactamase_156_133,TEM-1,beta-lactamase_156,P62593,1.00375,NO,133,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.186,-1.519,0.333,,,H,A,0.46,-0.86,0.805,,67.83,HHP,-0.988333,0.111618,0.00468022,1.00375 beta-lactamase_156_L167C,beta-lactamase_156_167,TEM-1,beta-lactamase_156,P62593,1.00375,NO,167,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.138,-4.763,3.625,,0.015,G,A,0.55,-0.63,0.4,,64.69,AHP,-1.30767,0.111618,0.00303566,1.00375 beta-lactamase_2500_A84S,beta-lactamase_2500_84,TEM-1,beta-lactamase_2500,P62593,1.00375,NO,84,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.651,-2.609,0.958,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.361275,0.00503822,1.00375 beta-lactamase_2500_L284M,beta-lactamase_2500_284,TEM-1,beta-lactamase_2500,P62593,1.00375,NO,284,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.361275,0.0686156,1.00375 beta-lactamase_625_E175W,beta-lactamase_625_175,TEM-1,beta-lactamase_625,P62593,1.00375,NO,175,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.336,-5.537,3.201,,0.551,,A,1.04,1.05,8.527,8.527,77.62,AAB,-1.31233,0.213352,0.00482205,1.00375 beta-lactamase_625_K53H,beta-lactamase_625_53,TEM-1,beta-lactamase_625,P62593,1.00375,NO,53,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-2.313,-4.67,2.357,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.213352,0.00383383,1.00375 Pab1_L191V,Pab1_191,Pab1,Pab1,P04147,1.00375,NO,191,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.2,-2.746,1.546,,0.204,E,B,,2.24,,,,HHP,-1.20133,0.175299,0.000583797,1.00375 beta-lactamase_2500_E61S,beta-lactamase_2500_61,TEM-1,beta-lactamase_2500,P62593,1.00376,NO,61,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.115,-2.688,0.573,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.361275,0.00440955,1.00376 beta-lactamase_2500_T112H,beta-lactamase_2500_112,TEM-1,beta-lactamase_2500,P62593,1.00376,NO,112,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.186,-4.734,2.548,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.361275,0.00531334,1.00376 beta-lactamase_39_S221K,beta-lactamase_39_221,TEM-1,beta-lactamase_39,P62593,1.00376,NO,221,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.754,-2.447,0.693,,0.624,H,A,0.27,-0.2,2.69,,74.48,BPH,-1.59967,0.0495842,0.0046094,1.00376 beta-lactamase_625_K286H,beta-lactamase_625_286,TEM-1,beta-lactamase_625,P62593,1.00376,NO,286,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.213352,,1.00376 beta-lactamase_625_L89W,beta-lactamase_625_89,TEM-1,beta-lactamase_625,P62593,1.00376,NO,89,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.096,-5.236,4.14,,0.168,T,A,0.55,0.63,1.599,,64.34,PHO,-1.75767,0.213352,0.00207068,1.00376 beta-lactamase_156_T126N,beta-lactamase_156_126,TEM-1,beta-lactamase_156,P62593,1.00377,NO,126,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.122,-3.467,2.345,,0.05,H,A,0.22,-0.05,1.14,,44.41,HPH,-1.60467,0.111618,0.00244552,1.00377 beta-lactamase_39_S266F,beta-lactamase_39_266,TEM-1,beta-lactamase_39,P62593,1.00377,NO,266,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.0495842,0.0140785,1.00377 PSD95pdz3_K380R,PSD95pdz3_380,PSD95pdz3,PSD95pdz3,P31016,1.00377,NO,380,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.416,-2.715,1.299,5.87979,,,,,19.6722,,,,HBP,-1.391,0.0758425,0.000281399,1.00377 beta-lactamase_156_T147Y,beta-lactamase_156_147,TEM-1,beta-lactamase_156,P62593,1.00378,NO,147,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.149,-4.243,3.094,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.111618,0.00226017,1.00378 beta-lactamase_625_M270Q,beta-lactamase_625_270,TEM-1,beta-lactamase_625,P62593,1.00378,NO,270,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.213352,0.00767762,1.00378 beta-lactamase_625_S283K,beta-lactamase_625_283,TEM-1,beta-lactamase_625,P62593,1.00378,NO,283,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.213352,0.0429138,1.00378 beta-lactamase_D177D,beta-lactamase_177,TEM-1,beta-lactamase,P62593,1.00378,NO,177,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.967,-0.967,,5.08038,0.006,T,L,1.59,-1.02,3.536,,64.69,BAP,-0.873667,0.221079,0.000864022,1.00378 beta-lactamase_39_R273T,beta-lactamase_39_273,TEM-1,beta-lactamase_39,P62593,1.00379,NO,273,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.314,-3.558,1.244,,0.564,H,A,1.2,1.57,2.163,,73.78,ABP,-1.841,0.0495842,0.0077952,1.00379 beta-lactamase_H94W,beta-lactamase_94,TEM-1,beta-lactamase,P62593,1.00379,NO,94,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-2.5,-5.512,3.012,6.1507,0.776,,B,0.63,1.24,1.176,,77.62,HBH,-1.872,0.221079,0.00389226,1.00379 beta-lactamase_I206F,beta-lactamase_206,TEM-1,beta-lactamase,P62593,1.00379,NO,206,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-2.429,-4.165,1.736,5.3727,0.173,H,A,1,-0.34,2.061,,77.62,HHA,-1.805,0.221079,0.00528934,1.00379 beta-lactamase_Q37S,beta-lactamase_37,TEM-1,beta-lactamase,P62593,1.00379,NO,37,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.134,-2.839,0.705,5.69153,0.613,H,A,0.12,1.98,1.318,,73.08,APH,-2.06967,0.221079,0.00425833,1.00379 beta-lactamase_2500_M180Q,beta-lactamase_2500_180,TEM-1,beta-lactamase_2500,P62593,1.0038,NO,180,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-2.795,-3.924,1.129,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.361275,0.00552048,1.0038 beta-lactamase_39_A246S,beta-lactamase_39_246,TEM-1,beta-lactamase_39,P62593,1.0038,NO,246,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.121,-3.607,1.486,,0.01,E,B,0.46,-1.01,1.331,,73.78,HHH,-1.55633,0.0495842,0.00569458,1.0038 beta-lactamase_625_I140L,beta-lactamase_625_140,TEM-1,beta-lactamase_625,P62593,1.0038,NO,140,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.733,-1.622,-0.111,,0.128,H,A,0.48,0.41,1.628,,73.08,PHO,-1.48733,0.213352,0.00597777,1.0038 kka2_1:2_R38C,kka2_1:2_38,Kka2,kka2_1:2,P00552,1.0038,NO,38,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.207,-4.996,3.789,,0.355,E,B,1.2,-1.13,6.872,6.872,52.27,HBH,-1.28567,0.295029,0.00372499,1.0038 beta-lactamase_2500_Q204I,beta-lactamase_2500_204,TEM-1,beta-lactamase_2500,P62593,1.00381,NO,204,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-1.382,-3.968,2.586,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.361275,0.00364106,1.00381 beta-lactamase_39_T178S,beta-lactamase_39_178,TEM-1,beta-lactamase_39,P62593,1.00381,NO,178,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-0.791,-2.936,2.145,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.0495842,0.000684366,1.00381 beta-lactamase_625_T116P,beta-lactamase_625_116,TEM-1,beta-lactamase_625,P62593,1.00381,NO,116,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.28,-3.831,2.551,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.213352,0.00336175,1.00381 beta-lactamase_156_T139C,beta-lactamase_156_139,TEM-1,beta-lactamase_156,P62593,1.00382,NO,139,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.901,-4.964,3.063,,0.216,H,A,0.22,0.39,16.34,16.34,77.62,PPH,-2.04667,0.111618,0.00441837,1.00382 beta-lactamase_39_H94W,beta-lactamase_39_94,TEM-1,beta-lactamase_39,P62593,1.00382,NO,94,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-2.5,-5.512,3.012,,0.776,,B,0.17,1.24,11.583,11.583,77.62,HBH,-1.872,0.0495842,0.00389226,1.00382 beta-lactamase_625_I140V,beta-lactamase_625_140,TEM-1,beta-lactamase_625,P62593,1.00382,NO,140,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.733,-1.662,-0.071,,0.128,H,A,0.48,0.41,1.628,,73.08,PHO,-1.48733,0.213352,0.00597777,1.00382 beta-lactamase_625_P217C,beta-lactamase_625_217,TEM-1,beta-lactamase_625,P62593,1.00382,NO,217,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-2.062,-5.064,3.002,,0.496,I,A,0.52,-0.33,1.087,,74.48,OOH,-1.64333,0.213352,0.00463211,1.00382 beta-lactamase_625_Q37T,beta-lactamase_625_37,TEM-1,beta-lactamase_625,P62593,1.00382,NO,37,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.134,-2.508,0.374,,0.613,H,A,0.64,1.98,1.318,,73.08,APH,-2.06967,0.213352,0.00425833,1.00382 gb1_Q228C,gb1_228,gb1,gb1,P06654,1.00382,NO,228,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,,,,,,,,,,,,,OPH,-1.282,0.177985,0.00391043,1.00382 beta-lactamase_156_R92A,beta-lactamase_156_92,TEM-1,beta-lactamase_156,P62593,1.00383,NO,92,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.718,-2.705,0.987,,0.479,E,B,1.2,1.36,19.112,19.112,65.38,BBH,-1.50367,0.111618,0.00429626,1.00383 beta-lactamase_625_P60Q,beta-lactamase_625_60,TEM-1,beta-lactamase_625,P62593,1.00383,NO,60,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-2.469,-3.986,1.517,,0.256,T,A,0.52,-0.56,3.653,,77.62,BOA,-1.97633,0.213352,0.00521318,1.00383 beta-lactamase_D250K,beta-lactamase_250,TEM-1,beta-lactamase,P62593,1.00383,NO,250,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.335,-2.899,0.564,5.72026,0.89,T,L,0.23,1.53,24.737,24.737,66.08,OAO,-1.85133,0.221079,0.00550899,1.00383 PSD95pdz3_R312Y,PSD95pdz3_312,PSD95pdz3,PSD95pdz3,P31016,1.00383,NO,312,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.582,-3.844,2.262,5.76826,,,,,12.2409,,,,OBB,-1.46667,0.0758425,0.00196255,1.00383 beta-lactamase_39_A34N,beta-lactamase_39_34,TEM-1,beta-lactamase_39,P62593,1.00384,NO,34,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.059,-3.965,1.906,,,H,A,0.46,-0.54,13.292,13.292,73.78,AHA,-1.74967,0.0495842,0.00407913,1.00384 beta-lactamase_625_A84G,beta-lactamase_625_84,TEM-1,beta-lactamase_625,P62593,1.00384,NO,84,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.651,-3.358,1.707,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.213352,0.00503822,1.00384 beta-lactamase_156_A230S,beta-lactamase_156_230,TEM-1,beta-lactamase_156,P62593,1.00385,NO,230,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.154,-2.48,1.326,,0.01,E,B,0.46,-1.17,2.179,,50,HHA,-1.079,0.111618,0.00516841,1.00385 beta-lactamase_39_H156Q,beta-lactamase_39_156,TEM-1,beta-lactamase_39,P62593,1.00385,NO,156,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-3.156,-2.776,-0.38,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.0495842,0.00468596,1.00385 beta-lactamase_625_E166M,beta-lactamase_625_166,TEM-1,beta-lactamase_625,P62593,1.00385,NO,166,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.756,-4.707,2.951,,0.508,G,A,1.04,1.05,2.124,,73.08,OAH,-1.42233,0.213352,0.00512989,1.00385 beta-lactamase_625_E175I,beta-lactamase_625_175,TEM-1,beta-lactamase_625,P62593,1.00385,NO,175,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.336,-3.797,1.461,,0.551,,A,1.04,1.05,8.527,8.527,77.62,AAB,-1.31233,0.213352,0.00482205,1.00385 beta-lactamase_625_M270G,beta-lactamase_625_270,TEM-1,beta-lactamase_625,P62593,1.00385,NO,270,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.213352,0.00767762,1.00385 beta-lactamase_0_G249K,beta-lactamase_0_249,TEM-1,beta-lactamase_0,P62593,1.00386,NO,249,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.0500837,0.00220169,1.00386 beta-lactamase_2500_L188M,beta-lactamase_2500_188,TEM-1,beta-lactamase_2500,P62593,1.00386,NO,188,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.166,-2.706,1.54,,,H,A,0.55,-0.3,17.865,17.865,60.14,PHB,-1.47033,0.361275,0.00295687,1.00386 beta-lactamase_625_A278F,beta-lactamase_625_278,TEM-1,beta-lactamase_625,P62593,1.00386,NO,278,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.213352,0.0310297,1.00386 beta-lactamase_156_L135E,beta-lactamase_156_135,TEM-1,beta-lactamase_156,P62593,1.00387,NO,135,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.002,-3.919,2.917,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.111618,0.00244423,1.00387 beta-lactamase_39_E145L,beta-lactamase_39_145,TEM-1,beta-lactamase_39,P62593,1.00387,NO,145,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.357,-3.644,1.287,,0.545,H,A,1.04,0.79,1.199,,77.62,BAH,-2.069,0.0495842,0.00553285,1.00387 beta-lactamase_39_L219V,beta-lactamase_39_219,TEM-1,beta-lactamase_39,P62593,1.00387,NO,219,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.313,-2.847,1.534,,,I,A,0.55,-0.51,19.842,19.842,74.48,HHB,-1.21533,0.0495842,0.00664345,1.00387 beta-lactamase_39_T138L,beta-lactamase_39_138,TEM-1,beta-lactamase_39,P62593,1.00388,NO,138,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.506,-3.638,1.132,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.0495842,0.00487868,1.00388 beta-lactamase_625_E238A,beta-lactamase_625_238,TEM-1,beta-lactamase_625,P62593,1.00388,NO,238,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.213352,0.00743256,1.00388 beta-lactamase_625_W288M,beta-lactamase_625_288,TEM-1,beta-lactamase_625,P62593,1.00388,NO,288,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,,,,,,,,,,,,,BHO,,0.213352,,1.00388 beta-lactamase_156_D271R,beta-lactamase_156_271,TEM-1,beta-lactamase_156,P62593,1.00389,NO,271,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.249,-3.747,2.498,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.111618,0.00752082,1.00389 beta-lactamase_156_G114S,beta-lactamase_156_114,TEM-1,beta-lactamase_156,P62593,1.00389,NO,114,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.094,-2.588,1.494,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.111618,0.00224919,1.00389 beta-lactamase_156_V214S,beta-lactamase_156_214,TEM-1,beta-lactamase_156,P62593,1.00389,NO,214,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.299,-3.408,2.109,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.111618,0.00628442,1.00389 beta-lactamase_2500_P172E,beta-lactamase_2500_172,TEM-1,beta-lactamase_2500,P62593,1.00389,NO,172,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.998,-3.52,2.522,,0.639,T,b,0.52,0.24,4.99,,74.48,HOP,-2.03067,0.361275,0.00312594,1.00389 beta-lactamase_156_Q37H,beta-lactamase_156_37,TEM-1,beta-lactamase_156,P62593,1.0039,NO,37,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.134,-3.314,1.18,,0.613,H,A,0.64,1.98,12.052,12.052,73.08,APH,-2.06967,0.111618,0.00425833,1.0039 beta-lactamase_39_G243S,beta-lactamase_39_243,TEM-1,beta-lactamase_39,P62593,1.0039,NO,243,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.0495842,0.00464034,1.0039 kka2_1:8_A150I,kka2_1:8_150,Kka2,kka2_1:8,P00552,1.0039,NO,150,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.949,-3.788,2.839,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.100394,0.0045009,1.0039 kka2_1:8_A150I,kka2_1:8_150,Kka2,kka2_1:8,P00552,1.0039,NO,150,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.949,-3.788,2.839,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.100394,0.0045009,1.0039 Pab1_P200H,Pab1_200,Pab1,Pab1,P04147,1.00391,NO,200,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.871,-4.631,2.76,,,,,,,3.877,,80.59,HOO,-1.7005,0.175299,0.00190795,1.00391 PSD95pdz3_G322K,PSD95pdz3_322,PSD95pdz3,PSD95pdz3,P31016,1.00391,NO,322,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.008,-3.364,2.356,5.24791,,,,,16.3275,,,,POH,-1.24867,0.0758425,0.00105821,1.00391 beta-lactamase_156_T116L,beta-lactamase_156_116,TEM-1,beta-lactamase_156,P62593,1.00392,NO,116,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.28,-3.376,2.096,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.111618,0.00336175,1.00392 beta-lactamase_156_T269H,beta-lactamase_156_269,TEM-1,beta-lactamase_156,P62593,1.00392,NO,269,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.111618,0.00950944,1.00392 beta-lactamase_625_E108T,beta-lactamase_625_108,TEM-1,beta-lactamase_625,P62593,1.00392,NO,108,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.46,-3.526,2.066,,0.572,G,A,1.04,1.87,20.151,20.151,72.73,PAB,-1.437,0.213352,0.00413372,1.00392 beta-lactamase_625_T263M,beta-lactamase_625_263,TEM-1,beta-lactamase_625,P62593,1.00392,NO,263,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.213352,0.0110582,1.00392 beta-lactamase_0_P172A,beta-lactamase_0_172,TEM-1,beta-lactamase_0,P62593,1.00393,NO,172,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.998,-2.44,1.442,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.0500837,0.00312594,1.00393 beta-lactamase_2500_E46Q,beta-lactamase_2500_46,TEM-1,beta-lactamase_2500,P62593,1.00393,NO,46,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.94,-4.007,2.067,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.361275,0.00427568,1.00393 beta-lactamase_39_I140G,beta-lactamase_39_140,TEM-1,beta-lactamase_39,P62593,1.00393,NO,140,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.733,-3.828,2.095,,0.128,H,A,0.48,0.41,1.16,,73.08,PHO,-1.48733,0.0495842,0.00597777,1.00393 beta-lactamase_G90A,beta-lactamase_90,TEM-1,beta-lactamase,P62593,1.00393,NO,90,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-2.091,-2.713,0.622,5.51991,0.598,T,A,0.23,0.32,1.791,,77.62,HOB,-1.52633,0.221079,0.00490273,1.00393 beta-lactamase_156_F149Q,beta-lactamase_156_149,TEM-1,beta-lactamase_156,P62593,1.00394,NO,149,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.299,-4.204,2.905,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.111618,0.00418462,1.00394 beta-lactamase_156_Q37Y,beta-lactamase_156_37,TEM-1,beta-lactamase_156,P62593,1.00394,NO,37,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.134,-4.193,2.059,,0.613,H,A,0.64,1.98,12.052,12.052,73.08,APH,-2.06967,0.111618,0.00425833,1.00394 beta-lactamase_2500_H156M,beta-lactamase_2500_156,TEM-1,beta-lactamase_2500,P62593,1.00394,NO,156,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-3.156,-3.543,0.387,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.361275,0.00468596,1.00394 beta-lactamase_2500_S283V,beta-lactamase_2500_283,TEM-1,beta-lactamase_2500,P62593,1.00394,NO,283,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.361275,0.0429138,1.00394 beta-lactamase_39_L28Q,beta-lactamase_39_28,TEM-1,beta-lactamase_39,P62593,1.00394,NO,28,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.579,-2.97,1.391,,0.277,H,A,0.55,-0.16,3.262,,93.01,PHH,-2.11333,0.0495842,0.00359321,1.00394 beta-lactamase_39_N274L,beta-lactamase_39_274,TEM-1,beta-lactamase_39,P62593,1.00394,NO,274,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.0495842,0.0110418,1.00394 beta-lactamase_625_N152A,beta-lactamase_625_152,TEM-1,beta-lactamase_625,P62593,1.00394,NO,152,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-2.757,-2.374,-0.383,,0.863,H,A,0.61,0.92,2.061,,77.62,BPH,-2.97,0.213352,0.00471429,1.00394 beta-lactamase_A266K,beta-lactamase_266,TEM-1,beta-lactamase,P62593,1.00394,NO,266,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.369,-3.571,2.202,5.02057,0.175,S,B,0.52,0.07,1.832,,64.34,PHP,-2.08567,0.221079,0.0140785,1.00394 beta-lactamase_2500_E238P,beta-lactamase_2500_238,TEM-1,beta-lactamase_2500,P62593,1.00395,NO,238,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.361275,0.00743256,1.00395 beta-lactamase_39_C121I,beta-lactamase_39_121,TEM-1,beta-lactamase_39,P62593,1.00395,NO,121,C,I,CI,Special,Hydrophobic,5.07,6.02,0.95,198,121,131,10,108.5,166.7,58.2,-0.953,-3.628,2.675,,,H,A,0.46,-0.81,7.644,,63.29,HOP,-1.46767,0.0495842,0.000744322,1.00395 beta-lactamase_625_Q86G,beta-lactamase_625_86,TEM-1,beta-lactamase_625,P62593,1.00395,NO,86,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.4,-2.887,0.487,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.213352,0.00450027,1.00395 beta-lactamase_625_S256I,beta-lactamase_625_256,TEM-1,beta-lactamase_625,P62593,1.00395,NO,256,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.621,-3.676,2.055,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.213352,0.00710634,1.00395 beta-lactamase_A200R,beta-lactamase_200,TEM-1,beta-lactamase,P62593,1.00395,NO,200,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.878,-2.634,0.756,5.19406,0.757,H,A,0.47,-0.19,0.436,,77.62,HHP,-2.001,0.221079,0.0060056,1.00395 beta-lactamase_K213R,beta-lactamase_213,TEM-1,beta-lactamase,P62593,1.00395,NO,213,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.81,-1.968,0.158,5.63167,0.67,,A,1.59,0.29,3.924,,67.83,ABH,-1.57767,0.221079,0.00610411,1.00395 PSD95pdz3_K380F,PSD95pdz3_380,PSD95pdz3,PSD95pdz3,P31016,1.00395,NO,380,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.416,-3.974,2.558,5.87979,,,,,19.6722,,,,HBP,-1.391,0.0758425,0.000281399,1.00395 beta-lactamase_2500_K53D,beta-lactamase_2500_53,TEM-1,beta-lactamase_2500,P62593,1.00396,NO,53,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-2.313,-3.725,1.412,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.361275,0.00383383,1.00396 beta-lactamase_2500_Q267I,beta-lactamase_2500_267,TEM-1,beta-lactamase_2500,P62593,1.00397,NO,267,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.361275,0.0102128,1.00397 beta-lactamase_39_L38H,beta-lactamase_39_38,TEM-1,beta-lactamase_39,P62593,1.00397,NO,38,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.343,-3.182,1.839,,0.088,H,A,0.55,0.2,17.089,17.089,64.34,PHO,-1.78033,0.0495842,0.00373244,1.00397 gb1_V247L,gb1_247,gb1,gb1,P06654,1.00397,NO,247,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.711,-2.624,0.913,,,,,,,0.805,,44.87,HHA,-1.485,0.177985,0.00435373,1.00397 beta-lactamase_156_A247Q,beta-lactamase_156_247,TEM-1,beta-lactamase_156,P62593,1.00398,NO,247,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.111618,0.00611275,1.00398 beta-lactamase_625_S266A,beta-lactamase_625_266,TEM-1,beta-lactamase_625,P62593,1.00398,NO,266,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.369,-2.686,1.317,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.213352,0.0140785,1.00398 beta-lactamase_A200A,beta-lactamase_200,TEM-1,beta-lactamase,P62593,1.00398,NO,200,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.878,-1.878,,5.19406,0.757,H,A,0.47,-0.19,0.436,,77.62,HHP,-2.001,0.221079,0.0060056,1.00398 beta-lactamase_A211C,beta-lactamase_211,TEM-1,beta-lactamase,P62593,1.00398,NO,211,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.896,-5.066,3.17,5.54662,0.369,T,A,0.52,-0.69,2.061,,77.62,AHA,-1.94633,0.221079,0.00648183,1.00398 beta-lactamase_A34A,beta-lactamase_34,TEM-1,beta-lactamase,P62593,1.00398,NO,34,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.059,-2.059,,4.9129,,H,A,0.75,-0.54,3.614,,73.78,AHA,-1.74967,0.221079,0.00407913,1.00398 beta-lactamase_Q203V,beta-lactamase_203,TEM-1,beta-lactamase,P62593,1.00398,NO,203,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.168,-3.605,1.437,5.65296,0.47,H,A,0.12,-0.38,1.66,,65.38,BPP,-1.614,0.221079,0.00631514,1.00398 beta-lactamase_156_F70L,beta-lactamase_156_70,TEM-1,beta-lactamase_156,P62593,1.00399,NO,70,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.169,-2.96,1.791,,,H,A,0.58,-1.34,1.918,,63.99,PHB,-0.980667,0.111618,0.00193499,1.00399 beta-lactamase_156_K32T,beta-lactamase_156_32,TEM-1,beta-lactamase_156,P62593,1.00399,NO,32,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.984,-2.479,0.495,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.111618,0.00401283,1.00399 beta-lactamase_156_R242V,beta-lactamase_156_242,TEM-1,beta-lactamase_156,P62593,1.00399,NO,242,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.111618,0.00452879,1.00399 beta-lactamase_39_L160Y,beta-lactamase_39_160,TEM-1,beta-lactamase_39,P62593,1.00399,NO,160,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.977,-3.98,3.003,,0.022,,B,0.55,-0.6,0.895,,44.41,BHA,-0.936,0.0495842,0.00193775,1.00399 beta-lactamase_39_G281N,beta-lactamase_39_281,TEM-1,beta-lactamase_39,P62593,1.00401,NO,281,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.0495842,0.0406482,1.00401 beta-lactamase_156_R273N,beta-lactamase_156_273,TEM-1,beta-lactamase_156,P62593,1.00402,NO,273,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.314,-3.744,1.43,,0.564,H,A,1.2,1.57,20.248,20.248,73.78,ABP,-1.841,0.111618,0.0077952,1.00402 beta-lactamase_2500_P255M,beta-lactamase_2500_255,TEM-1,beta-lactamase_2500,P62593,1.00402,NO,255,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.361275,0.00499612,1.00402 beta-lactamase_39_L218R,beta-lactamase_39_218,TEM-1,beta-lactamase_39,P62593,1.00402,NO,218,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.391,-2.276,0.885,,,I,b,0.55,-0.53,2.038,,74.48,OHH,-1.58867,0.0495842,0.00618274,1.00402 beta-lactamase_R189S,beta-lactamase_189,TEM-1,beta-lactamase,P62593,1.00402,NO,189,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.844,-2.849,1.005,5.74877,0.278,H,A,0.68,1.01,1.512,,72.73,HBB,-1.668,0.221079,0.0050699,1.00402 beta-lactamase_2500_L47M,beta-lactamase_2500_47,TEM-1,beta-lactamase_2500,P62593,1.00403,NO,47,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.876,-2.629,0.753,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.361275,0.00439844,1.00403 beta-lactamase_39_R118G,beta-lactamase_39_118,TEM-1,beta-lactamase_39,P62593,1.00403,NO,118,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.413,-1.757,-0.656,,0.457,H,A,1.2,1.39,3.961,,77.62,HBA,-1.785,0.0495842,0.00538794,1.00403 beta-lactamase_625_E108I,beta-lactamase_625_108,TEM-1,beta-lactamase_625,P62593,1.00403,NO,108,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.46,-4.133,2.673,,0.572,G,A,1.04,1.87,20.151,20.151,72.73,PAB,-1.437,0.213352,0.00413372,1.00403 beta-lactamase_625_E145I,beta-lactamase_625_145,TEM-1,beta-lactamase_625,P62593,1.00403,NO,145,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.357,-4.11,1.753,,0.545,H,A,1.04,0.79,2.64,,77.62,BAH,-2.069,0.213352,0.00553285,1.00403 beta-lactamase_625_G39Y,beta-lactamase_625_39,TEM-1,beta-lactamase_625,P62593,1.00403,NO,39,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.864,-4.383,2.519,,0.701,T,L,0.29,0.47,29.926,29.926,77.62,HOH,-1.53633,0.213352,0.00487611,1.00403 beta-lactamase_0_R41D,beta-lactamase_0_41,TEM-1,beta-lactamase_0,P62593,1.00404,NO,41,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-0.942,-3.657,2.715,,0.321,E,B,1.2,-0.07,2.68,,65.03,HBH,-1.30267,0.0500837,0.00123327,1.00404 beta-lactamase_156_D48I,beta-lactamase_156_48,TEM-1,beta-lactamase_156,P62593,1.00404,NO,48,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.101,-4.047,2.946,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.111618,0.0027273,1.00404 beta-lactamase_39_T198E,beta-lactamase_39_198,TEM-1,beta-lactamase_39,P62593,1.00404,NO,198,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.168,-3.379,1.211,,0.489,,B,0.22,-0.13,3.614,,73.78,HPH,-1.98767,0.0495842,0.004311,1.00404 beta-lactamase_625_A282S,beta-lactamase_625_282,TEM-1,beta-lactamase_625,P62593,1.00404,NO,282,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.213352,0.0449821,1.00404 beta-lactamase_0_I245G,beta-lactamase_0_245,TEM-1,beta-lactamase_0,P62593,1.00405,NO,245,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.0500837,0.00391032,1.00405 beta-lactamase_39_H151V,beta-lactamase_39_151,TEM-1,beta-lactamase_39,P62593,1.00405,NO,151,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-2.96,-3.785,0.825,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.0495842,0.00216946,1.00405 beta-lactamase_S254N,beta-lactamase_254,TEM-1,beta-lactamase,P62593,1.00405,NO,254,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.126,-3.697,1.571,5.49575,0.312,,a,0.25,-0.48,24.91,24.91,69.58,OPB,-2.215,0.221079,0.00369,1.00405 beta-lactamase_T267G,beta-lactamase_267,TEM-1,beta-lactamase,P62593,1.00405,NO,267,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.308,-3.323,1.015,5.28263,0.54,,B,0.69,-0.14,0.374,,73.78,HPH,-1.9,0.221079,0.0102128,1.00405 kka2_1:1_E3Q,kka2_1:1_3,Kka2,kka2_1:1,P00552,1.00405,NO,3,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.199,-3.602,1.403,,,,,,,3.435,,92.05,HAP,-2.11567,0.520039,0.00267607,1.00405 beta-lactamase_625_S201A,beta-lactamase_625_201,TEM-1,beta-lactamase_625,P62593,1.00406,NO,201,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.183,-2.127,0.944,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.213352,0.00198815,1.00406 kka2_1:2_A166E,kka2_1:2_166,Kka2,kka2_1:2,P00552,1.00406,NO,166,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.407,-2.752,0.345,,0.534,.,B,0.46,1.03,23.175,23.175,71.59,HHO,-2.421,0.295029,0.00799912,1.00406 PSD95pdz3_A390L,PSD95pdz3_390,PSD95pdz3,PSD95pdz3,P31016,1.00406,NO,390,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.307,-2.815,1.508,5.03823,,,,,12.46,,,,HHP,-1.54467,0.0758425,0.00104603,1.00406 PSD95pdz3_L353T,PSD95pdz3_353,PSD95pdz3,PSD95pdz3,P31016,1.00406,NO,353,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.347,-3.103,1.756,5.81136,,,,,17.3525,,,,AHB,-1.50533,0.0758425,0.000664742,1.00406 beta-lactamase_39_G253H,beta-lactamase_39_253,TEM-1,beta-lactamase_39,P62593,1.00407,NO,253,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.0495842,0.00786358,1.00407 beta-lactamase_625_D36S,beta-lactamase_625_36,TEM-1,beta-lactamase_625,P62593,1.00407,NO,36,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.732,-2.107,-0.625,,0.555,H,A,0.75,1.17,2.26,,77.62,AAP,-1.91167,0.213352,0.00476483,1.00407 beta-lactamase_39_G226D,beta-lactamase_39_226,TEM-1,beta-lactamase_39,P62593,1.00408,NO,226,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.461,-1.914,0.453,,0.701,T,l,0.29,-0.25,23.034,23.034,74.48,HOH,-1.42933,0.0495842,0.00665294,1.00408 beta-lactamase_156_L191S,beta-lactamase_156_191,TEM-1,beta-lactamase_156,P62593,1.00409,NO,191,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.087,-3.562,2.475,,,H,A,0.55,0.09,1.372,,63.29,BHH,-1.445,0.111618,0.00263549,1.00409 beta-lactamase_156_E195Q,beta-lactamase_156_195,TEM-1,beta-lactamase_156,P62593,1.0041,NO,195,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.186,-2.527,0.341,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.111618,0.00496565,1.0041 beta-lactamase_625_I93M,beta-lactamase_625_93,TEM-1,beta-lactamase_625,P62593,1.0041,NO,93,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.401,-4.189,2.788,,0.128,E,B,0.48,0.44,1.524,,67.83,BHB,-1.873,0.213352,0.00527066,1.0041 beta-lactamase_156_P217T,beta-lactamase_156_217,TEM-1,beta-lactamase_156,P62593,1.00411,NO,217,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-2.062,-2.679,0.617,,0.496,I,A,0.52,-0.33,2.303,,74.48,OOH,-1.64333,0.111618,0.00463211,1.00411 beta-lactamase_2500_Q37L,beta-lactamase_2500_37,TEM-1,beta-lactamase_2500,P62593,1.00411,NO,37,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.134,-2.893,0.759,,0.613,H,A,0.64,1.98,1.318,,73.08,APH,-2.06967,0.361275,0.00425833,1.00411 kka2_1:8_D250T,kka2_1:8_250,Kka2,kka2_1:8,P00552,1.00411,NO,250,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.015,-3.493,2.478,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.100394,0.0177103,1.00411 kka2_1:8_D250T,kka2_1:8_250,Kka2,kka2_1:8,P00552,1.00411,NO,250,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.015,-3.493,2.478,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.100394,0.0177103,1.00411 beta-lactamase_0_P250R,beta-lactamase_0_250,TEM-1,beta-lactamase_0,P62593,1.00412,NO,250,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.0500837,0.00550899,1.00412 beta-lactamase_2500_N173A,beta-lactamase_2500_173,TEM-1,beta-lactamase_2500,P62593,1.00412,NO,173,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-2.663,-2.432,-0.231,,1.044,T,l,0.61,1.25,1.88,,77.62,OPA,-1.46633,0.361275,0.0033769,1.00412 beta-lactamase_39_L150C,beta-lactamase_39_150,TEM-1,beta-lactamase_39,P62593,1.00412,NO,150,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.326,-4.732,3.406,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.0495842,0.00463171,1.00412 beta-lactamase_625_A225C,beta-lactamase_625_225,TEM-1,beta-lactamase_625,P62593,1.00412,NO,225,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.845,-5.105,3.26,,1,T,B,0.46,-0.38,9.874,9.874,74.48,OHO,-1.39967,0.213352,0.00465057,1.00412 beta-lactamase_N173N,beta-lactamase_173,TEM-1,beta-lactamase,P62593,1.00412,NO,173,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-2.663,-2.663,,7.02497,1.044,T,l,0.09,1.25,1.88,,77.62,OPA,-1.46633,0.221079,0.0033769,1.00412 beta-lactamase_625_E169M,beta-lactamase_625_169,TEM-1,beta-lactamase_625,P62593,1.00413,NO,169,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.23,-4.676,3.446,,0.337,,A,1.04,1,1.806,,73.08,PAH,-1.16533,0.213352,0.00400994,1.00413 beta-lactamase_E61R,beta-lactamase_61,TEM-1,beta-lactamase,P62593,1.00413,NO,61,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.115,-3.845,1.73,6.29701,0.775,T,a,0.52,1.29,1.975,,77.62,OAA,-1.92567,0.221079,0.00440955,1.00413 beta-lactamase_156_L73F,beta-lactamase_156_73,TEM-1,beta-lactamase_156,P62593,1.00414,NO,73,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.507,-2.19,0.683,,,H,A,0.55,-0.64,2.09,,67.83,HHH,-1.487,0.111618,0.00488983,1.00414 beta-lactamase_156_V106S,beta-lactamase_156_106,TEM-1,beta-lactamase_156,P62593,1.00414,NO,106,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.218,-3.705,2.487,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.111618,0.00304168,1.00414 beta-lactamase_625_A182Y,beta-lactamase_625_182,TEM-1,beta-lactamase_625,P62593,1.00414,NO,182,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.777,-4.299,2.522,,0.136,H,A,0.46,-0.66,16.784,16.784,93.01,OHH,-1.27367,0.213352,0.00559099,1.00414 beta-lactamase_156_T147S,beta-lactamase_156_147,TEM-1,beta-lactamase_156,P62593,1.00415,NO,147,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.149,-2.487,1.338,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.111618,0.00226017,1.00415 beta-lactamase_39_L55D,beta-lactamase_39_55,TEM-1,beta-lactamase_39,P62593,1.00415,NO,55,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.86,-4.094,2.234,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.0495842,0.00403741,1.00415 beta-lactamase_625_A34T,beta-lactamase_625_34,TEM-1,beta-lactamase_625,P62593,1.00415,NO,34,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.059,-2.5,0.441,,,H,A,0.46,-0.54,3.614,,73.78,AHA,-1.74967,0.213352,0.00407913,1.00415 beta-lactamase_625_N50W,beta-lactamase_625_50,TEM-1,beta-lactamase_625,P62593,1.00415,NO,50,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-2.979,-5.454,2.475,,0.912,T,A,0.61,1.24,3.446,,77.62,HPP,-2.134,0.213352,0.0047211,1.00415 beta-lactamase_156_L248A,beta-lactamase_156_248,TEM-1,beta-lactamase_156,P62593,1.00416,NO,248,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.111618,0.00428493,1.00416 beta-lactamase_625_K30H,beta-lactamase_625_30,TEM-1,beta-lactamase_625,P62593,1.00416,NO,30,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-2.307,-4.558,2.251,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.213352,0.00448593,1.00416 beta-lactamase_625_N152W,beta-lactamase_625_152,TEM-1,beta-lactamase_625,P62593,1.00416,NO,152,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-2.757,-5.472,2.715,,0.863,H,A,0.61,0.92,2.061,,77.62,BPH,-2.97,0.213352,0.00471429,1.00416 beta-lactamase_156_E61S,beta-lactamase_156_61,TEM-1,beta-lactamase_156,P62593,1.00417,NO,61,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.115,-2.688,0.573,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.111618,0.00440955,1.00417 beta-lactamase_39_N134F,beta-lactamase_39_134,TEM-1,beta-lactamase_39,P62593,1.00417,NO,134,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-0.879,-4.318,3.439,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.0495842,0.000644786,1.00417 Pab1_G167S,Pab1_167,Pab1,Pab1,P04147,1.00417,NO,167,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.223,-3.148,1.925,,0.195,S,g,,0.03,,,,BOH,-1.25133,0.175299,0.00146449,1.00417 beta-lactamase_625_A123S,beta-lactamase_625_123,TEM-1,beta-lactamase_625,P62593,1.00418,NO,123,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.834,-3.019,2.185,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.213352,0.0010157,1.00418 beta-lactamase_625_K286Y,beta-lactamase_625_286,TEM-1,beta-lactamase_625,P62593,1.00418,NO,286,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.213352,,1.00418 beta-lactamase_156_L55N,beta-lactamase_156_55,TEM-1,beta-lactamase_156,P62593,1.0042,NO,55,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.86,-4.216,2.356,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.111618,0.00403741,1.0042 beta-lactamase_A266M,beta-lactamase_266,TEM-1,beta-lactamase,P62593,1.0042,NO,266,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.369,-4.512,3.143,5.02057,0.175,S,B,0.52,0.07,1.832,,64.34,PHP,-2.08567,0.221079,0.0140785,1.0042 beta-lactamase_K284L,beta-lactamase_284,TEM-1,beta-lactamase,P62593,1.0042,NO,284,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.981,-3.504,1.523,6.30084,0.848,H,A,1.82,0.67,1.931,,77.62,HBB,-1.82133,0.221079,0.0686156,1.0042 beta-lactamase_S2T,beta-lactamase_2,TEM-1,beta-lactamase,P62593,1.0042,NO,2,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.942,-3.09,1.148,,,,,,,2.36,,65.38,HPH,-2.02767,0.221079,0.00227352,1.0042 beta-lactamase_39_Q97F,beta-lactamase_39_97,TEM-1,beta-lactamase_39,P62593,1.00421,NO,97,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.072,-4.44,2.368,,0.823,G,A,0.64,2.42,4.457,,77.62,PPP,-2.43833,0.0495842,0.0045116,1.00421 beta-lactamase_39_S241V,beta-lactamase_39_241,TEM-1,beta-lactamase_39,P62593,1.00421,NO,241,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.0495842,0.00452736,1.00421 beta-lactamase_625_R41D,beta-lactamase_625_41,TEM-1,beta-lactamase_625,P62593,1.00421,NO,41,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-0.942,-3.657,2.715,,0.321,E,B,1.2,-0.07,1.186,,65.03,HBH,-1.30267,0.213352,0.00123327,1.00421 beta-lactamase_156_D99I,beta-lactamase_156_99,TEM-1,beta-lactamase_156,P62593,1.00422,NO,99,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.191,-3.979,2.788,,0.402,G,A,0.75,0.36,3.529,,64.69,PAH,-1.794,0.111618,0.00305446,1.00422 beta-lactamase_156_E166R,beta-lactamase_156_166,TEM-1,beta-lactamase_156,P62593,1.00422,NO,166,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.756,-3.805,2.049,,0.508,G,A,1.04,1.05,2.393,,73.08,OAH,-1.42233,0.111618,0.00512989,1.00422 beta-lactamase_625_G154C,beta-lactamase_625_154,TEM-1,beta-lactamase_625,P62593,1.00422,NO,154,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.823,-5.058,4.235,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.213352,0.00180205,1.00422 beta-lactamase_625_V214K,beta-lactamase_625_214,TEM-1,beta-lactamase_625,P62593,1.00422,NO,214,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.299,-3.699,2.4,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.213352,0.00628442,1.00422 Pab1_H134L,Pab1_134,Pab1,Pab1,P04147,1.00422,NO,134,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-1.542,-3.57,2.028,,,,,,,,,,HBO,-1.346,0.175299,0.00116356,1.00422 beta-lactamase_156_K213M,beta-lactamase_156_213,TEM-1,beta-lactamase_156,P62593,1.00423,NO,213,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.81,-4.653,2.843,,0.67,,A,2.34,0.29,3.924,,67.83,ABH,-1.57767,0.111618,0.00610411,1.00423 beta-lactamase_39_I245S,beta-lactamase_39_245,TEM-1,beta-lactamase_39,P62593,1.00423,NO,245,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.0495842,0.00391032,1.00423 beta-lactamase_39_L137Y,beta-lactamase_39_137,TEM-1,beta-lactamase_39,P62593,1.00423,NO,137,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.03,-4.002,2.972,,,H,A,0.55,-0.38,0.674,,42.31,HHP,-1.58933,0.0495842,0.00278599,1.00423 beta-lactamase_625_E169H,beta-lactamase_625_169,TEM-1,beta-lactamase_625,P62593,1.00423,NO,169,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.23,-4.45,3.22,,0.337,,A,1.04,1,1.806,,73.08,PAH,-1.16533,0.213352,0.00400994,1.00423 beta-lactamase_39_E56K,beta-lactamase_39_56,TEM-1,beta-lactamase_39,P62593,1.00424,NO,56,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.043,-3.327,1.284,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.0495842,0.00238534,1.00424 beta-lactamase_A222V,beta-lactamase_222,TEM-1,beta-lactamase,P62593,1.00424,NO,222,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.103,-1.973,-0.13,5.2262,0.233,H,A,0.47,-0.25,0.379,,77.62,PHH,-1.63733,0.221079,0.00466094,1.00424 beta-lactamase_39_S96T,beta-lactamase_39_96,TEM-1,beta-lactamase_39,P62593,1.00425,NO,96,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.27,-2.436,0.166,,0.368,,b,0.27,0.39,2.516,,73.78,HPP,-2.019,0.0495842,0.00551835,1.00425 beta-lactamase_625_S96A,beta-lactamase_625_96,TEM-1,beta-lactamase_625,P62593,1.00425,NO,96,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.27,-2.75,0.48,,0.368,,b,0.27,0.39,5.244,,73.78,HPP,-2.019,0.213352,0.00551835,1.00425 beta-lactamase_625_T116K,beta-lactamase_625_116,TEM-1,beta-lactamase_625,P62593,1.00425,NO,116,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.28,-3.42,2.14,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.213352,0.00336175,1.00425 beta-lactamase_156_A222Y,beta-lactamase_156_222,TEM-1,beta-lactamase_156,P62593,1.00426,NO,222,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.103,-4.186,2.083,,0.233,H,A,0.46,-0.25,2.461,,77.62,PHH,-1.63733,0.111618,0.00466094,1.00426 beta-lactamase_156_T193D,beta-lactamase_156_193,TEM-1,beta-lactamase_156,P62593,1.00426,NO,193,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.914,-3.815,1.901,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.111618,0.00482669,1.00426 beta-lactamase_39_A222H,beta-lactamase_39_222,TEM-1,beta-lactamase_39,P62593,1.00426,NO,222,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.103,-2.705,0.602,,0.233,H,A,0.46,-0.25,1.448,,77.62,PHH,-1.63733,0.0495842,0.00466094,1.00426 beta-lactamase_625_D271T,beta-lactamase_625_271,TEM-1,beta-lactamase_625,P62593,1.00426,NO,271,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.213352,0.00752082,1.00426 beta-lactamase_625_R91T,beta-lactamase_625_91,TEM-1,beta-lactamase_625,P62593,1.00426,NO,91,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.392,-2.721,1.329,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.213352,0.00380226,1.00426 beta-lactamase_625_L199M,beta-lactamase_625_199,TEM-1,beta-lactamase_625,P62593,1.00427,NO,199,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-2.942,-4.728,1.786,,0.832,H,A,0.55,0.42,1.552,,77.62,PHH,-2.32933,0.213352,0.0048649,1.00427 beta-lactamase_156_S96T,beta-lactamase_156_96,TEM-1,beta-lactamase_156,P62593,1.00428,NO,96,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.27,-2.436,0.166,,0.368,,b,0.27,0.39,2.838,,73.78,HPP,-2.019,0.111618,0.00551835,1.00428 beta-lactamase_2500_H24K,beta-lactamase_2500_24,TEM-1,beta-lactamase_2500,P62593,1.00428,NO,24,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-2.481,-3.455,0.974,,,,,,,0.467,,93.01,OBO,-2.0035,0.361275,0.00238894,1.00428 beta-lactamase_625_A40V,beta-lactamase_625_40,TEM-1,beta-lactamase_625,P62593,1.00428,NO,40,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.402,-2.649,1.247,,0.155,S,B,0.46,0.21,1.357,,73.78,OHB,-1.40267,0.213352,0.00490026,1.00428 beta-lactamase_625_L55H,beta-lactamase_625_55,TEM-1,beta-lactamase_625,P62593,1.00428,NO,55,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.86,-4.855,2.995,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.213352,0.00403741,1.00428 beta-lactamase_625_V157M,beta-lactamase_625_157,TEM-1,beta-lactamase_625,P62593,1.00428,NO,157,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.751,-2.587,0.836,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.213352,0.00506849,1.00428 kka2_1:1_V46G,kka2_1:1_46,Kka2,kka2_1:1,P00552,1.00428,NO,46,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-2.62,-2.793,0.173,,0.192,.,B,0.44,-1.12,20.149,20.149,92.05,OHH,-1.88633,0.520039,0.00631301,1.00428 beta-lactamase_156_T198R,beta-lactamase_156_198,TEM-1,beta-lactamase_156,P62593,1.00429,NO,198,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.168,-3.752,1.584,,0.489,,B,0.22,-0.13,10.771,10.771,73.78,HPH,-1.98767,0.111618,0.004311,1.00429 beta-lactamase_625_E210L,beta-lactamase_625_210,TEM-1,beta-lactamase_625,P62593,1.00429,NO,210,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.319,-2.05,-0.269,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.213352,0.00663582,1.00429 beta-lactamase_625_L28R,beta-lactamase_625_28,TEM-1,beta-lactamase_625,P62593,1.00429,NO,28,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.579,-2.903,1.324,,0.277,H,A,0.55,-0.16,2.716,,93.01,PHH,-2.11333,0.213352,0.00359321,1.00429 beta-lactamase_156_E166G,beta-lactamase_156_166,TEM-1,beta-lactamase_156,P62593,1.0043,NO,166,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.756,-2.741,0.985,,0.508,G,A,1.04,1.05,2.393,,73.08,OAH,-1.42233,0.111618,0.00512989,1.0043 beta-lactamase_156_R159Q,beta-lactamase_156_159,TEM-1,beta-lactamase_156,P62593,1.0043,NO,159,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-0.94,-3.498,2.558,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.111618,0.00108472,1.0043 beta-lactamase_625_A123G,beta-lactamase_625_123,TEM-1,beta-lactamase_625,P62593,1.0043,NO,123,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.834,-2.991,2.157,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.213352,0.0010157,1.0043 beta-lactamase_R189A,beta-lactamase_189,TEM-1,beta-lactamase,P62593,1.0043,NO,189,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.844,-2.739,0.895,5.74877,0.278,H,A,0.68,1.01,1.512,,72.73,HBB,-1.668,0.221079,0.0050699,1.0043 beta-lactamase_156_L73V,beta-lactamase_156_73,TEM-1,beta-lactamase_156,P62593,1.00431,NO,73,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.507,-2.286,0.779,,,H,A,0.55,-0.64,2.09,,67.83,HHH,-1.487,0.111618,0.00488983,1.00431 beta-lactamase_39_K53I,beta-lactamase_39_53,TEM-1,beta-lactamase_39,P62593,1.00431,NO,53,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-2.313,-4.015,1.702,,0.589,,B,2.34,1.15,15.633,15.633,77.62,OBH,-2.1,0.0495842,0.00383383,1.00431 beta-lactamase_39_S104P,beta-lactamase_39_104,TEM-1,beta-lactamase_39,P62593,1.00431,NO,104,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.015,-3.751,2.736,,0.04,,b,0.27,0.57,4.02,,63.29,HPO,-1.05267,0.0495842,0.00218083,1.00431 beta-lactamase_156_F58Q,beta-lactamase_156_58,TEM-1,beta-lactamase_156,P62593,1.00432,NO,58,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-2.914,-2.803,-0.111,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.111618,0.00523369,1.00432 beta-lactamase_156_K30G,beta-lactamase_156_30,TEM-1,beta-lactamase_156,P62593,1.00432,NO,30,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-2.307,-3.406,1.099,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.111618,0.00448593,1.00432 beta-lactamase_625_D113K,beta-lactamase_625_113,TEM-1,beta-lactamase_625,P62593,1.00432,NO,113,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.829,-2.696,0.867,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.213352,0.00474112,1.00432 beta-lactamase_625_S96N,beta-lactamase_625_96,TEM-1,beta-lactamase_625,P62593,1.00432,NO,96,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.27,-3.037,0.767,,0.368,,b,0.27,0.39,5.244,,73.78,HPP,-2.019,0.213352,0.00551835,1.00432 beta-lactamase_0_D113L,beta-lactamase_0_113,TEM-1,beta-lactamase_0,P62593,1.00433,NO,113,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.829,-3.651,1.822,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.0500837,0.00474112,1.00433 beta-lactamase_156_L120A,beta-lactamase_156_120,TEM-1,beta-lactamase_156,P62593,1.00433,NO,120,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.044,-3.203,2.159,,,H,A,0.55,-1.13,7.813,,64.69,AHO,-1.13633,0.111618,0.00143563,1.00433 beta-lactamase_625_F70W,beta-lactamase_625_70,TEM-1,beta-lactamase_625,P62593,1.00433,NO,70,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.169,-4.623,3.454,,,H,A,0.58,-1.34,1.14,,63.99,PHB,-0.980667,0.213352,0.00193499,1.00433 beta-lactamase_625_R41V,beta-lactamase_625_41,TEM-1,beta-lactamase_625,P62593,1.00433,NO,41,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-0.942,-3.751,2.809,,0.321,E,B,1.2,-0.07,1.186,,65.03,HBH,-1.30267,0.213352,0.00123327,1.00433 beta-lactamase_N152K,beta-lactamase_152,TEM-1,beta-lactamase,P62593,1.00433,NO,152,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-2.757,-2.892,0.135,5.98571,0.863,H,A,0.09,0.92,2.061,,77.62,BPH,-2.97,0.221079,0.00471429,1.00433 beta-lactamase_39_S96A,beta-lactamase_39_96,TEM-1,beta-lactamase_39,P62593,1.00434,NO,96,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.27,-2.75,0.48,,0.368,,b,0.27,0.39,2.516,,73.78,HPP,-2.019,0.0495842,0.00551835,1.00434 beta-lactamase_625_A200M,beta-lactamase_625_200,TEM-1,beta-lactamase_625,P62593,1.00434,NO,200,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.878,-4.732,2.854,,0.757,H,A,0.46,-0.19,12.672,12.672,77.62,HHP,-2.001,0.213352,0.0060056,1.00434 beta-lactamase_625_E56K,beta-lactamase_625_56,TEM-1,beta-lactamase_625,P62593,1.00434,NO,56,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.043,-3.327,1.284,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.213352,0.00238534,1.00434 beta-lactamase_625_G39S,beta-lactamase_625_39,TEM-1,beta-lactamase_625,P62593,1.00434,NO,39,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.864,-2.342,0.478,,0.701,T,L,0.29,0.47,29.926,29.926,77.62,HOH,-1.53633,0.213352,0.00487611,1.00434 kka2_1:8_F203L,kka2_1:8_203,Kka2,kka2_1:8,P00552,1.00434,NO,203,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-0.911,-2.161,1.25,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.100394,0.00318738,1.00434 kka2_1:8_F203L,kka2_1:8_203,Kka2,kka2_1:8,P00552,1.00434,NO,203,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-0.911,-2.161,1.25,,0.26,E,B,0.58,-0.92,0.91,,63.64,BHP,-1.34167,0.100394,0.00318738,1.00434 beta-lactamase_156_A148L,beta-lactamase_156_148,TEM-1,beta-lactamase_156,P62593,1.00435,NO,148,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.757,-3.596,1.839,,0.379,H,A,0.46,-0.55,3.551,,72.73,PHH,-1.40167,0.111618,0.00547053,1.00435 beta-lactamase_156_H110W,beta-lactamase_156_110,TEM-1,beta-lactamase_156,P62593,1.00435,NO,110,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-1.706,-5.185,3.479,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.111618,0.00441499,1.00435 beta-lactamase_156_S221V,beta-lactamase_156_221,TEM-1,beta-lactamase_156,P62593,1.00435,NO,221,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.754,-3.416,1.662,,0.624,H,A,0.27,-0.2,17.729,17.729,74.48,BPH,-1.59967,0.111618,0.0046094,1.00435 beta-lactamase_39_R41H,beta-lactamase_39_41,TEM-1,beta-lactamase_39,P62593,1.00435,NO,41,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-0.942,-4.279,3.337,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.0495842,0.00123327,1.00435 beta-lactamase_625_E166G,beta-lactamase_625_166,TEM-1,beta-lactamase_625,P62593,1.00435,NO,166,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.756,-2.741,0.985,,0.508,G,A,1.04,1.05,2.124,,73.08,OAH,-1.42233,0.213352,0.00512989,1.00435 beta-lactamase_625_M180V,beta-lactamase_625_180,TEM-1,beta-lactamase_625,P62593,1.00435,NO,180,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-2.795,-3.273,0.478,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.213352,0.00552048,1.00435 beta-lactamase_625_R118E,beta-lactamase_625_118,TEM-1,beta-lactamase_625,P62593,1.00435,NO,118,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.413,-2.454,0.041,,0.457,H,A,1.2,1.39,2.144,,77.62,HBA,-1.785,0.213352,0.00538794,1.00435 beta-lactamase_156_P143T,beta-lactamase_156_143,TEM-1,beta-lactamase_156,P62593,1.00436,NO,143,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.967,-2.616,1.649,,0.075,H,A,0.52,-0.37,0.479,,66.78,OOB,-1.354,0.111618,0.00114551,1.00436 beta-lactamase_39_P65E,beta-lactamase_39_65,TEM-1,beta-lactamase_39,P62593,1.00436,NO,65,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.894,-3.524,2.63,,0.098,E,B,0.52,-0.62,0.623,,40.56,HOH,-1.03233,0.0495842,0.00152776,1.00436 beta-lactamase_I3I,beta-lactamase_3,TEM-1,beta-lactamase,P62593,1.00438,NO,3,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-2.143,-2.143,,,,,,,,3.946,,93.01,PHP,-2.21633,0.221079,0.00349304,1.00438 beta-lactamase_L146M,beta-lactamase_146,TEM-1,beta-lactamase,P62593,1.00438,NO,146,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.462,-4.183,2.721,5.62483,0.007,H,A,1.3,-0.56,1.953,,64.69,AHP,-1.656,0.221079,0.00474542,1.00438 beta-lactamase_L223T,beta-lactamase_223,TEM-1,beta-lactamase,P62593,1.00438,NO,223,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.055,-2.595,1.54,5.42318,0.27,,B,1.3,0.09,1.511,,74.48,HHO,-1.35033,0.221079,0.00372793,1.00438 beta-lactamase_N50Y,beta-lactamase_50,TEM-1,beta-lactamase,P62593,1.00438,NO,50,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-2.979,-4.3,1.321,5.51261,0.912,T,A,1.07,1.24,1.581,,77.62,HPP,-2.134,0.221079,0.0047211,1.00438 beta-lactamase_39_L197H,beta-lactamase_39_197,TEM-1,beta-lactamase_39,P62593,1.00439,NO,197,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.853,-4.903,4.05,,0.007,S,B,0.55,0.33,1.559,,60.14,HHP,-1.833,0.0495842,0.00144602,1.00439 beta-lactamase_39_P165A,beta-lactamase_39_165,TEM-1,beta-lactamase_39,P62593,1.00439,NO,165,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.373,-3.022,1.649,,0.203,T,A,0.52,-0.31,3.907,,73.78,AOA,-1.359,0.0495842,0.00549538,1.00439 beta-lactamase_V117V,beta-lactamase_117,TEM-1,beta-lactamase,P62593,1.00439,NO,117,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.53,-1.53,,5.33594,,H,A,1.19,-0.34,1.182,,65.03,PHB,-1.741,0.221079,0.00467906,1.00439 beta-lactamase_2500_E195D,beta-lactamase_2500_195,TEM-1,beta-lactamase_2500,P62593,1.0044,NO,195,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.186,-1.979,-0.207,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.361275,0.00496565,1.0044 beta-lactamase_2500_I171E,beta-lactamase_2500_171,TEM-1,beta-lactamase_2500,P62593,1.0044,NO,171,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-2.431,-3.643,1.212,,0.361,,B,0.48,0.53,1.66,,77.62,HHO,-1.55533,0.361275,0.00623355,1.0044 beta-lactamase_39_N274Q,beta-lactamase_39_274,TEM-1,beta-lactamase_39,P62593,1.00441,NO,274,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-2.082,-3.838,1.756,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.0495842,0.0110418,1.00441 PSD95pdz3_G364S,PSD95pdz3_364,PSD95pdz3,PSD95pdz3,P31016,1.00441,NO,364,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.008,-2.842,1.834,5.53299,,,,,21.28,,,,POH,-1.33667,0.0758425,0.00050942,1.00441 beta-lactamase_2500_Q86N,beta-lactamase_2500_86,TEM-1,beta-lactamase_2500,P62593,1.00442,NO,86,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.4,-3.754,1.354,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.361275,0.00450027,1.00442 beta-lactamase_39_R81D,beta-lactamase_39_81,TEM-1,beta-lactamase_39,P62593,1.00442,NO,81,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.466,-3.611,2.145,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.0495842,0.00499763,1.00442 E1_Ubiquitin_K48S,E1_Ubiquitin_48,Uba1,E1_Ubiquitin,P0CG63,1.00442,NO,48,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.219,-3.031,1.812,,0.132,E,B,,-0.28,,,,OBO,-1.109,0.18783,0.00100363,1.00442 E1_Ubiquitin_Q40M,E1_Ubiquitin_40,Uba1,E1_Ubiquitin,P0CG63,1.00442,NO,40,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-1.48,-4.321,2.841,,0.387,G,A,,0.03,,,,OPP,-1.365,0.18783,0.0037961,1.00442 E1_Ubiquitin_Q40S,E1_Ubiquitin_40,Uba1,E1_Ubiquitin,P0CG63,1.00442,NO,40,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-1.48,-3.114,1.634,,0.387,G,A,,0.03,,,,OPP,-1.365,0.18783,0.0037961,1.00442 E1_Ubiquitin_Q41H,E1_Ubiquitin_41,Uba1,E1_Ubiquitin,P0CG63,1.00442,NO,41,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-1.25,-4.047,2.797,,0.017,E,B,,-0.98,,,,PPB,-1.344,0.18783,0.00215097,1.00442 Pab1_E161H,Pab1_161,Pab1,Pab1,P04147,1.00442,NO,161,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.474,-4.26,2.786,,0.663,T,a,,1.34,,,,AAP,-1.59067,0.175299,0.00276141,1.00442 beta-lactamase_39_E119M,beta-lactamase_39_119,TEM-1,beta-lactamase_39,P62593,1.00443,NO,119,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.412,-4.79,3.378,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.0495842,0.00386966,1.00443 beta-lactamase_39_L196K,beta-lactamase_39_196,TEM-1,beta-lactamase_39,P62593,1.00443,NO,196,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-2.478,-3.633,1.155,,0.518,S,A,0.55,1.35,12.152,12.152,77.62,AHH,-1.839,0.0495842,0.00512144,1.00443 beta-lactamase_39_S104Y,beta-lactamase_39_104,TEM-1,beta-lactamase_39,P62593,1.00443,NO,104,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.015,-4.223,3.208,,0.04,,b,0.27,0.57,4.02,,63.29,HPO,-1.05267,0.0495842,0.00218083,1.00443 beta-lactamase_156_G52P,beta-lactamase_156_52,TEM-1,beta-lactamase_156,P62593,1.00444,NO,52,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.149,-2.849,1.7,,0.299,,l,0.29,-0.04,1.179,,64.69,POB,-1.66267,0.111618,0.00340138,1.00444 beta-lactamase_156_I54P,beta-lactamase_156_54,TEM-1,beta-lactamase_156,P62593,1.00444,NO,54,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-2.838,-4.045,1.207,,0.669,E,B,0.48,-0.14,0.541,,73.78,BHH,-2.337,0.111618,0.00403589,1.00444 beta-lactamase_39_E238W,beta-lactamase_39_238,TEM-1,beta-lactamase_39,P62593,1.00444,NO,238,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.0495842,0.00743256,1.00444 beta-lactamase_2500_R118G,beta-lactamase_2500_118,TEM-1,beta-lactamase_2500,P62593,1.00445,NO,118,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.413,-1.757,-0.656,,0.457,H,A,1.2,1.39,2.144,,77.62,HBA,-1.785,0.361275,0.00538794,1.00445 beta-lactamase_625_S80N,beta-lactamase_625_80,TEM-1,beta-lactamase_625,P62593,1.00445,NO,80,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.029,-2.999,0.97,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.213352,0.00565569,1.00445 beta-lactamase_625_V157C,beta-lactamase_625_157,TEM-1,beta-lactamase_625,P62593,1.00445,NO,157,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.751,-4.91,3.159,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.213352,0.00506849,1.00445 WW_domain_I193Y,WW_domain_193,Yap65,WW_domain,P46937,1.00445,NO,193,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.993,-3.966,1.973,6.15906,,,,,,1.833,,83.33,BHA,-1.756,0.153962,0.00587613,1.00445 beta-lactamase_156_S96Q,beta-lactamase_156_96,TEM-1,beta-lactamase_156,P62593,1.00446,NO,96,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.27,-2.919,0.649,,0.368,,b,0.27,0.39,2.838,,73.78,HPP,-2.019,0.111618,0.00551835,1.00446 beta-lactamase_2500_L135I,beta-lactamase_2500_135,TEM-1,beta-lactamase_2500,P62593,1.00446,NO,135,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.002,-2.037,1.035,,0.117,H,A,0.55,-0.58,0.795,,43.71,PHH,-1.03767,0.361275,0.00244423,1.00446 beta-lactamase_39_K30F,beta-lactamase_39_30,TEM-1,beta-lactamase_39,P62593,1.00446,NO,30,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-2.307,-4.338,2.031,,0.142,H,A,2.34,-0.65,6.717,,93.01,HBH,-2.32833,0.0495842,0.00448593,1.00446 beta-lactamase_156_I245L,beta-lactamase_156_245,TEM-1,beta-lactamase_156,P62593,1.00447,NO,245,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.111618,0.00391032,1.00447 beta-lactamase_2500_L199A,beta-lactamase_2500_199,TEM-1,beta-lactamase_2500,P62593,1.00447,NO,199,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-2.942,-2.055,-0.887,,0.832,H,A,0.55,0.42,15.504,15.504,77.62,PHH,-2.32933,0.361275,0.0048649,1.00447 beta-lactamase_625_M67T,beta-lactamase_625_67,TEM-1,beta-lactamase_625,P62593,1.00447,NO,67,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-2.231,-3.488,1.257,,0.006,G,P,0.55,-0.81,2.653,,65.03,HHP,-1.502,0.213352,0.00409753,1.00447 beta-lactamase_156_P165T,beta-lactamase_156_165,TEM-1,beta-lactamase_156,P62593,1.00448,NO,165,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.373,-1.281,-0.092,,0.203,T,A,0.52,-0.31,3.907,,73.78,AOA,-1.359,0.111618,0.00549538,1.00448 beta-lactamase_39_M270N,beta-lactamase_39_270,TEM-1,beta-lactamase_39,P62593,1.00448,NO,270,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.0495842,0.00767762,1.00448 beta-lactamase_L10A,beta-lactamase_10,TEM-1,beta-lactamase,P62593,1.00448,NO,10,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.623,-3.024,1.401,,,,,,,2.467,,65.38,HHH,-1.83833,0.221079,0.00296968,1.00448 beta-lactamase_T139I,beta-lactamase_139,TEM-1,beta-lactamase,P62593,1.00448,NO,139,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.901,-3.075,1.174,5.69095,0.216,H,A,0.3,0.39,2.256,,77.62,PPH,-2.04667,0.221079,0.00441837,1.00448 beta-lactamase_39_S51E,beta-lactamase_39_51,TEM-1,beta-lactamase_39,P62593,1.00449,NO,51,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.526,-3.428,1.902,,0.496,T,A,0.27,0.26,2.964,,72.73,PPO,-1.88467,0.0495842,0.00504821,1.00449 beta-lactamase_2500_G194T,beta-lactamase_2500_194,TEM-1,beta-lactamase_2500,P62593,1.0045,NO,194,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.396,-2.79,1.394,,0.276,S,b,0.29,0.36,3.593,,67.83,POA,-1.832,0.361275,0.00392163,1.0045 beta-lactamase_39_A246M,beta-lactamase_39_246,TEM-1,beta-lactamase_39,P62593,1.0045,NO,246,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.121,-2.882,0.761,,0.01,E,B,0.46,-1.01,1.331,,73.78,HHH,-1.55633,0.0495842,0.00569458,1.0045 beta-lactamase_39_I245N,beta-lactamase_39_245,TEM-1,beta-lactamase_39,P62593,1.0045,NO,245,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.0495842,0.00391032,1.0045 beta-lactamase_156_A200H,beta-lactamase_156_200,TEM-1,beta-lactamase_156,P62593,1.00451,NO,200,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.878,-4.732,2.854,,0.757,H,A,0.46,-0.19,16.368,16.368,77.62,HHP,-2.001,0.111618,0.0060056,1.00451 beta-lactamase_156_K144S,beta-lactamase_156_144,TEM-1,beta-lactamase_156,P62593,1.00451,NO,144,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-2.388,-2.51,0.122,,0.863,H,A,2.34,1.27,2.073,,77.62,OBA,-1.904,0.111618,0.00481141,1.00451 beta-lactamase_625_G142D,beta-lactamase_625_142,TEM-1,beta-lactamase_625,P62593,1.00451,NO,142,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.707,-3.466,2.759,,0.034,,p,0.29,-0.64,1.35,,64.69,OOO,-0.834,0.213352,0.00060149,1.00451 beta-lactamase_625_L192M,beta-lactamase_625_192,TEM-1,beta-lactamase_625,P62593,1.00451,NO,192,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.254,-4.084,2.83,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.213352,0.00558728,1.00451 beta-lactamase_625_P60E,beta-lactamase_625_60,TEM-1,beta-lactamase_625,P62593,1.00451,NO,60,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-2.469,-2.856,0.387,,0.256,T,A,0.52,-0.56,3.653,,77.62,BOA,-1.97633,0.213352,0.00521318,1.00451 beta-lactamase_39_L49G,beta-lactamase_39_49,TEM-1,beta-lactamase_39,P62593,1.00452,NO,49,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.897,-3.581,1.684,,0.131,T,A,0.55,0.04,13.838,13.838,64.69,AHP,-1.99233,0.0495842,0.00401477,1.00452 beta-lactamase_D83D,beta-lactamase_83,TEM-1,beta-lactamase,P62593,1.00452,NO,83,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.066,-1.066,,5.40616,0.354,H,A,1.33,0.22,0.861,,48.95,HAH,-1.34733,0.221079,0.00205968,1.00452 beta-lactamase_156_A77V,beta-lactamase_156_77,TEM-1,beta-lactamase_156,P62593,1.00453,NO,77,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.234,-2.654,1.42,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.111618,0.00282362,1.00453 beta-lactamase_2500_K109Q,beta-lactamase_2500_109,TEM-1,beta-lactamase_2500,P62593,1.00453,NO,109,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.734,-2.855,1.121,,0.787,G,A,2.34,2.21,0.998,,72.73,ABB,-1.63333,0.361275,0.00462493,1.00453 beta-lactamase_156_R159H,beta-lactamase_156_159,TEM-1,beta-lactamase_156,P62593,1.00454,NO,159,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-0.94,-2.789,1.849,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.111618,0.00108472,1.00454 beta-lactamase_625_D271C,beta-lactamase_625_271,TEM-1,beta-lactamase_625,P62593,1.00454,NO,271,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.213352,0.00752082,1.00454 beta-lactamase_625_H94M,beta-lactamase_625_94,TEM-1,beta-lactamase_625,P62593,1.00454,NO,94,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-2.5,-3.474,0.974,,0.776,,B,0.17,1.24,19.42,19.42,77.62,HBH,-1.872,0.213352,0.00389226,1.00454 beta-lactamase_156_F149C,beta-lactamase_156_149,TEM-1,beta-lactamase_156,P62593,1.00455,NO,149,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.299,-4.94,3.641,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.111618,0.00418462,1.00455 beta-lactamase_39_N50W,beta-lactamase_39_50,TEM-1,beta-lactamase_39,P62593,1.00455,NO,50,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-2.979,-5.454,2.475,,0.912,T,A,0.61,1.24,10.736,,77.62,HPP,-2.134,0.0495842,0.0047211,1.00455 kka2_1:8_E161H,kka2_1:8_161,Kka2,kka2_1:8,P00552,1.00455,NO,161,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.581,-4.674,3.093,,0.829,G,A,1.04,2.24,11.923,11.923,92.05,AAB,-1.861,0.100394,0.00760103,1.00455 kka2_1:8_E161H,kka2_1:8_161,Kka2,kka2_1:8,P00552,1.00455,NO,161,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.581,-4.674,3.093,,0.829,G,A,1.04,2.24,11.923,11.923,92.05,AAB,-1.861,0.100394,0.00760103,1.00455 beta-lactamase_156_E279C,beta-lactamase_156_279,TEM-1,beta-lactamase_156,P62593,1.00456,NO,279,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.111618,0.0192826,1.00456 beta-lactamase_156_K286A,beta-lactamase_156_286,TEM-1,beta-lactamase_156,P62593,1.00456,NO,286,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.111618,,1.00456 beta-lactamase_625_G253F,beta-lactamase_625_253,TEM-1,beta-lactamase_625,P62593,1.00456,NO,253,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.213352,0.00786358,1.00456 beta-lactamase_625_L150I,beta-lactamase_625_150,TEM-1,beta-lactamase_625,P62593,1.00456,NO,150,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.326,-3.18,1.854,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.213352,0.00463171,1.00456 beta-lactamase_156_E210K,beta-lactamase_156_210,TEM-1,beta-lactamase_156,P62593,1.00457,NO,210,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.319,-2.868,0.549,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.111618,0.00663582,1.00457 beta-lactamase_625_A148S,beta-lactamase_625_148,TEM-1,beta-lactamase_625,P62593,1.00457,NO,148,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.757,-2.791,1.034,,0.379,H,A,0.46,-0.55,1.359,,72.73,PHH,-1.40167,0.213352,0.00547053,1.00457 beta-lactamase_156_C121V,beta-lactamase_156_121,TEM-1,beta-lactamase_156,P62593,1.00458,NO,121,C,V,CV,Special,Hydrophobic,5.07,5.60847,0.538465,192,121,117,-4,108.5,140,31.5,-0.953,-3.371,2.418,,,H,A,0.46,-0.81,1.136,,63.29,HOP,-1.46767,0.111618,0.000744322,1.00458 beta-lactamase_39_M184H,beta-lactamase_39_184,TEM-1,beta-lactamase_39,P62593,1.00458,NO,184,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.593,-4.818,3.225,,,H,A,0.55,-0.87,2.893,,62.94,HHH,-1.41,0.0495842,0.00356019,1.00458 beta-lactamase_39_R63D,beta-lactamase_39_63,TEM-1,beta-lactamase_39,P62593,1.00458,NO,63,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-0.943,-3.762,2.819,,0.218,,B,1.2,-0.31,0.326,,44.06,ABH,-0.992333,0.0495842,0.00126938,1.00458 beta-lactamase_39_Q86D,beta-lactamase_39_86,TEM-1,beta-lactamase_39,P62593,1.00459,NO,86,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.4,-2.27,-0.13,,0.696,S,A,0.64,2.38,27.704,27.704,77.62,OPA,-1.61067,0.0495842,0.00450027,1.00459 beta-lactamase_156_T126A,beta-lactamase_156_126,TEM-1,beta-lactamase_156,P62593,1.0046,NO,126,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.122,-2.955,1.833,,0.05,H,A,0.22,-0.05,1.14,,44.41,HPH,-1.60467,0.111618,0.00244552,1.0046 beta-lactamase_39_A185V,beta-lactamase_39_185,TEM-1,beta-lactamase_39,P62593,1.0046,NO,185,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.406,-2.093,0.687,,,H,A,0.46,-1.02,2.68,,65.03,HHP,-1.84033,0.0495842,0.00467449,1.0046 beta-lactamase_625_P143Q,beta-lactamase_625_143,TEM-1,beta-lactamase_625,P62593,1.0046,NO,143,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.967,-4.024,3.057,,0.075,H,A,0.52,-0.37,1.445,,66.78,OOB,-1.354,0.213352,0.00114551,1.0046 gb1_T243K,gb1_243,gb1,gb1,P06654,1.0046,NO,243,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.415,-3.268,1.853,,,,,,,1.083,,37.28,PPP,-1.43233,0.177985,0.00308687,1.0046 kka2_1:8_R145E,kka2_1:8_145,Kka2,kka2_1:8,P00552,1.0046,NO,145,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.804,-2.289,0.485,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.100394,0.00846663,1.0046 kka2_1:8_R145E,kka2_1:8_145,Kka2,kka2_1:8,P00552,1.0046,NO,145,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.804,-2.289,0.485,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.100394,0.00846663,1.0046 beta-lactamase_2500_A182F,beta-lactamase_2500_182,TEM-1,beta-lactamase_2500,P62593,1.00461,NO,182,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.777,-4.357,2.58,,0.136,H,A,0.46,-0.66,2.032,,93.01,OHH,-1.27367,0.361275,0.00559099,1.00461 beta-lactamase_39_L196T,beta-lactamase_39_196,TEM-1,beta-lactamase_39,P62593,1.00462,NO,196,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-2.478,-2.588,0.11,,0.518,S,A,0.55,1.35,12.152,12.152,77.62,AHH,-1.839,0.0495842,0.00512144,1.00462 Pab1_E161Y,Pab1_161,Pab1,Pab1,P04147,1.00462,NO,161,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.474,-4.174,2.7,,0.663,T,a,,1.34,,,,AAP,-1.59067,0.175299,0.00276141,1.00462 beta-lactamase_0_I277C,beta-lactamase_0_277,TEM-1,beta-lactamase_0,P62593,1.00463,NO,277,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.0500837,0.0169305,1.00463 beta-lactamase_156_M127L,beta-lactamase_156_127,TEM-1,beta-lactamase_156,P62593,1.00463,NO,127,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-2.251,-2.123,-0.128,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.111618,0.00437927,1.00463 beta-lactamase_156_V214F,beta-lactamase_156_214,TEM-1,beta-lactamase_156,P62593,1.00463,NO,214,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.299,-3.997,2.698,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.111618,0.00628442,1.00463 beta-lactamase_39_A77Y,beta-lactamase_39_77,TEM-1,beta-lactamase_39,P62593,1.00463,NO,77,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.234,-4.173,2.939,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.0495842,0.00282362,1.00463 beta-lactamase_39_Q276G,beta-lactamase_39_276,TEM-1,beta-lactamase_39,P62593,1.00463,NO,276,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.0495842,0.0191712,1.00463 beta-lactamase_39_S96D,beta-lactamase_39_96,TEM-1,beta-lactamase_39,P62593,1.00463,NO,96,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.27,-3.641,1.371,,0.368,,b,0.27,0.39,2.516,,73.78,HPP,-2.019,0.0495842,0.00551835,1.00463 beta-lactamase_39_T269M,beta-lactamase_39_269,TEM-1,beta-lactamase_39,P62593,1.00463,NO,269,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.156,,,,0.646,H,A,0.53,0.4,3.889,,77.62,HPH,-1.96733,0.0495842,0.00950944,1.00463 beta-lactamase_625_A235G,beta-lactamase_625_235,TEM-1,beta-lactamase_625,P62593,1.00463,NO,235,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.266,-2.075,0.809,,0.32,E,B,0.46,-0.86,0.281,,50,OHO,-0.89,0.213352,0.00493474,1.00463 beta-lactamase_K144T,beta-lactamase_144,TEM-1,beta-lactamase,P62593,1.00463,NO,144,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-2.388,-2.935,0.547,6.02507,0.863,H,A,2.81,1.27,0.515,,77.62,OBA,-1.904,0.221079,0.00481141,1.00463 beta-lactamase_156_E279M,beta-lactamase_156_279,TEM-1,beta-lactamase_156,P62593,1.00464,NO,279,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.111618,0.0192826,1.00464 beta-lactamase_39_F70M,beta-lactamase_39_70,TEM-1,beta-lactamase_39,P62593,1.00464,NO,70,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.169,-3.002,1.833,,,H,A,0.58,-1.34,1.14,,63.99,PHB,-0.980667,0.0495842,0.00193499,1.00464 beta-lactamase_625_I140C,beta-lactamase_625_140,TEM-1,beta-lactamase_625,P62593,1.00464,NO,140,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.733,-4.792,3.059,,0.128,H,A,0.48,0.41,1.628,,73.08,PHO,-1.48733,0.213352,0.00597777,1.00464 beta-lactamase_156_D36W,beta-lactamase_156_36,TEM-1,beta-lactamase_156,P62593,1.00465,NO,36,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.732,-5.422,2.69,,0.555,H,A,0.75,1.17,14.871,14.871,77.62,AAP,-1.91167,0.111618,0.00476483,1.00465 beta-lactamase_156_F149E,beta-lactamase_156_149,TEM-1,beta-lactamase_156,P62593,1.00465,NO,149,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.299,-3.842,2.543,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.111618,0.00418462,1.00465 beta-lactamase_625_K286V,beta-lactamase_625_286,TEM-1,beta-lactamase_625,P62593,1.00465,NO,286,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.213352,,1.00465 PSD95pdz3_I377R,PSD95pdz3_377,PSD95pdz3,PSD95pdz3,P31016,1.00465,NO,377,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.873,-3.879,2.006,4.9532,,,,,19.185,2.364,,87.71,HHH,-1.49567,0.0758425,0.000795475,1.00465 beta-lactamase_0_I277W,beta-lactamase_0_277,TEM-1,beta-lactamase_0,P62593,1.00466,NO,277,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.0500837,0.0169305,1.00466 beta-lactamase_156_G253N,beta-lactamase_156_253,TEM-1,beta-lactamase_156,P62593,1.00466,NO,253,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.111618,0.00786358,1.00466 beta-lactamase_39_L196C,beta-lactamase_39_196,TEM-1,beta-lactamase_39,P62593,1.00466,NO,196,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-2.478,-4.975,2.497,,0.518,S,A,0.55,1.35,12.152,12.152,77.62,AHH,-1.839,0.0495842,0.00512144,1.00466 Pab1_P135F,Pab1_135,Pab1,Pab1,P04147,1.00466,NO,135,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.457,-4.256,2.799,,,,,,,6.41,,81.8,BOA,-1.53367,0.175299,0.00148028,1.00466 beta-lactamase_156_M66Y,beta-lactamase_156_66,TEM-1,beta-lactamase_156,P62593,1.00467,NO,66,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.362,-4.034,2.672,,0.013,,A,0.55,-0.7,1.94,,73.08,OHH,-1.49567,0.111618,0.00412876,1.00467 beta-lactamase_156_R92S,beta-lactamase_156_92,TEM-1,beta-lactamase_156,P62593,1.00468,NO,92,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.718,-3.47,1.752,,0.479,E,B,1.2,1.36,19.112,19.112,65.38,BBH,-1.50367,0.111618,0.00429626,1.00468 beta-lactamase_2500_Q88H,beta-lactamase_2500_88,TEM-1,beta-lactamase_2500,P62593,1.00468,NO,88,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.086,-4.599,2.513,,0.807,,B,0.64,2.03,1.84,,77.62,APH,-1.53433,0.361275,0.00504167,1.00468 beta-lactamase_39_G194Q,beta-lactamase_39_194,TEM-1,beta-lactamase_39,P62593,1.00468,NO,194,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.396,-3.925,2.529,,0.276,S,b,0.29,0.36,4.852,,67.83,POA,-1.832,0.0495842,0.00392163,1.00468 beta-lactamase_39_G281Q,beta-lactamase_39_281,TEM-1,beta-lactamase_39,P62593,1.00468,NO,281,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.0495842,0.0406482,1.00468 beta-lactamase_156_P224G,beta-lactamase_156_224,TEM-1,beta-lactamase_156,P62593,1.00469,NO,224,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.893,-3.351,2.458,,0.383,,B,0.52,-0.3,0.383,,74.48,HOH,-1.26433,0.111618,0.00189564,1.00469 beta-lactamase_156_Q37N,beta-lactamase_156_37,TEM-1,beta-lactamase_156,P62593,1.00469,NO,37,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.134,-3.706,1.572,,0.613,H,A,0.64,1.98,12.052,12.052,73.08,APH,-2.06967,0.111618,0.00425833,1.00469 beta-lactamase_625_R189C,beta-lactamase_625_189,TEM-1,beta-lactamase_625,P62593,1.00469,NO,189,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.844,-5.229,3.385,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.213352,0.0050699,1.00469 beta-lactamase_H94R,beta-lactamase_94,TEM-1,beta-lactamase,P62593,1.00469,NO,94,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-2.5,-2.531,0.031,6.1507,0.776,,B,0.63,1.24,1.176,,77.62,HBH,-1.872,0.221079,0.00389226,1.00469 beta-lactamase_0_K144E,beta-lactamase_0_144,TEM-1,beta-lactamase_0,P62593,1.0047,NO,144,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-2.388,-2.372,-0.016,,0.863,H,A,2.34,1.27,5.696,,77.62,OBA,-1.904,0.0500837,0.00481141,1.0047 beta-lactamase_156_S256R,beta-lactamase_156_256,TEM-1,beta-lactamase_156,P62593,1.0047,NO,256,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.111618,0.00710634,1.0047 beta-lactamase_2500_I140V,beta-lactamase_2500_140,TEM-1,beta-lactamase_2500,P62593,1.0047,NO,140,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.733,-1.662,-0.071,,0.128,H,A,0.48,0.41,1.628,,73.08,PHO,-1.48733,0.361275,0.00597777,1.0047 beta-lactamase_2500_S221A,beta-lactamase_2500_221,TEM-1,beta-lactamase_2500,P62593,1.0047,NO,221,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.754,-1.332,-0.422,,0.624,H,A,0.27,-0.2,1.971,,74.48,BPH,-1.59967,0.361275,0.0046094,1.0047 beta-lactamase_39_G194D,beta-lactamase_39_194,TEM-1,beta-lactamase_39,P62593,1.0047,NO,194,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.396,-2.314,0.918,,0.276,S,b,0.29,0.36,4.852,,67.83,POA,-1.832,0.0495842,0.00392163,1.0047 beta-lactamase_39_P143C,beta-lactamase_39_143,TEM-1,beta-lactamase_39,P62593,1.0047,NO,143,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.967,-5.012,4.045,,0.075,H,A,0.52,-0.37,0.976,,66.78,OOB,-1.354,0.0495842,0.00114551,1.0047 beta-lactamase_39_T198R,beta-lactamase_39_198,TEM-1,beta-lactamase_39,P62593,1.0047,NO,198,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.168,-3.752,1.584,,0.489,,B,0.22,-0.13,3.614,,73.78,HPH,-1.98767,0.0495842,0.004311,1.0047 Pab1_E161Q,Pab1_161,Pab1,Pab1,P04147,1.0047,NO,161,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.474,-3.427,1.953,,0.663,T,a,,1.34,,,,AAP,-1.59067,0.175299,0.00276141,1.0047 beta-lactamase_156_S241A,beta-lactamase_156_241,TEM-1,beta-lactamase_156,P62593,1.00471,NO,241,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.111618,0.00452736,1.00471 beta-lactamase_156_T193G,beta-lactamase_156_193,TEM-1,beta-lactamase_156,P62593,1.00471,NO,193,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.914,-3.548,1.634,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.111618,0.00482669,1.00471 beta-lactamase_2500_R118T,beta-lactamase_2500_118,TEM-1,beta-lactamase_2500,P62593,1.00471,NO,118,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.413,-2.845,0.432,,0.457,H,A,1.2,1.39,2.144,,77.62,HBA,-1.785,0.361275,0.00538794,1.00471 beta-lactamase_39_V214D,beta-lactamase_39_214,TEM-1,beta-lactamase_39,P62593,1.00471,NO,214,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.299,-3.873,2.574,,0.375,S,A,0.44,-0.44,18.838,18.838,74.48,BHH,-1.53733,0.0495842,0.00628442,1.00471 beta-lactamase_625_V101E,beta-lactamase_625_101,TEM-1,beta-lactamase_625,P62593,1.00471,NO,101,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.295,-2.851,1.556,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.213352,0.00374492,1.00471 beta-lactamase_625_A211F,beta-lactamase_625_211,TEM-1,beta-lactamase_625,P62593,1.00472,NO,211,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.896,-4.364,2.468,,0.369,T,A,0.46,-0.69,2.061,,77.62,AHA,-1.94633,0.213352,0.00648183,1.00472 beta-lactamase_625_P172L,beta-lactamase_625_172,TEM-1,beta-lactamase_625,P62593,1.00472,NO,172,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.998,-2.658,1.66,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.213352,0.00312594,1.00472 beta-lactamase_S221K,beta-lactamase_221,TEM-1,beta-lactamase,P62593,1.00472,NO,221,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.754,-2.447,0.693,5.77407,0.624,H,A,0.74,-0.2,0.383,,74.48,BPH,-1.59967,0.221079,0.0046094,1.00472 beta-lactamase_2500_Q276H,beta-lactamase_2500_276,TEM-1,beta-lactamase_2500,P62593,1.00473,NO,276,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.361275,0.0191712,1.00473 beta-lactamase_625_T178S,beta-lactamase_625_178,TEM-1,beta-lactamase_625,P62593,1.00473,NO,178,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-0.791,-2.936,2.145,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.213352,0.000684366,1.00473 beta-lactamase_625_V260T,beta-lactamase_625_260,TEM-1,beta-lactamase_625,P62593,1.00473,NO,260,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.213352,0.00471757,1.00473 beta-lactamase_39_A84F,beta-lactamase_39_84,TEM-1,beta-lactamase_39,P62593,1.00474,NO,84,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.651,-4.366,2.715,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.0495842,0.00503822,1.00474 beta-lactamase_156_E210C,beta-lactamase_156_210,TEM-1,beta-lactamase_156,P62593,1.00475,NO,210,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.319,-4.991,2.672,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.111618,0.00663582,1.00475 beta-lactamase_625_L74A,beta-lactamase_625_74,TEM-1,beta-lactamase_625,P62593,1.00475,NO,74,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.296,-1.569,0.273,,,H,A,0.55,-0.91,0.895,,50,HHO,-1.34933,0.213352,0.00493255,1.00475 beta-lactamase_625_R63Y,beta-lactamase_625_63,TEM-1,beta-lactamase_625,P62593,1.00475,NO,63,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-0.943,-4.16,3.217,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.213352,0.00126938,1.00475 beta-lactamase_39_L74S,beta-lactamase_39_74,TEM-1,beta-lactamase_39,P62593,1.00476,NO,74,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.296,-3.399,2.103,,,H,A,0.55,-0.91,1.581,,50,HHO,-1.34933,0.0495842,0.00493255,1.00476 beta-lactamase_625_M270K,beta-lactamase_625_270,TEM-1,beta-lactamase_625,P62593,1.00476,NO,270,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.213352,0.00767762,1.00476 beta-lactamase_A200C,beta-lactamase_200,TEM-1,beta-lactamase,P62593,1.00476,NO,200,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.878,-5.005,3.127,5.19406,0.757,H,A,0.47,-0.19,0.436,,77.62,HHP,-2.001,0.221079,0.0060056,1.00476 beta-lactamase_156_G154S,beta-lactamase_156_154,TEM-1,beta-lactamase_156,P62593,1.00477,NO,154,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.823,-3.197,2.374,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.111618,0.00180205,1.00477 beta-lactamase_39_P25G,beta-lactamase_39_25,TEM-1,beta-lactamase_39,P62593,1.00477,NO,25,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.526,-2.198,0.672,,0.624,H,A,0.52,0.14,1.157,,73.08,BOA,-2.15367,0.0495842,0.00347571,1.00477 beta-lactamase_39_V157L,beta-lactamase_39_157,TEM-1,beta-lactamase_39,P62593,1.00477,NO,157,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.751,-3.066,1.315,,0.308,S,a,0.44,-0.75,10.364,10.364,69.58,BHP,-2.00767,0.0495842,0.00506849,1.00477 beta-lactamase_T186S,beta-lactamase_186,TEM-1,beta-lactamase,P62593,1.00477,NO,186,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.522,-2.471,-0.051,5.07364,0.396,H,A,0.3,-0.28,2.144,,77.62,HPP,-1.77633,0.221079,0.00485034,1.00477 kka2_1:4_P167R,kka2_1:4_167,Kka2,kka2_1:4,P00552,1.00477,NO,167,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-2.403,-4.046,1.643,,0.18,H,A,0.52,0.75,3.6,,64.39,HOH,-2.26633,0.168804,0.00543203,1.00477 PSD95pdz3_I377A,PSD95pdz3_377,PSD95pdz3,PSD95pdz3,P31016,1.00477,NO,377,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.873,-2.015,0.142,4.9532,,,,,19.185,2.364,,87.71,HHH,-1.49567,0.0758425,0.000795475,1.00477 beta-lactamase_156_P25L,beta-lactamase_156_25,TEM-1,beta-lactamase_156,P62593,1.00478,NO,25,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.526,-3.586,2.06,,0.624,H,A,0.52,0.14,1.079,,73.08,BOA,-2.15367,0.111618,0.00347571,1.00478 beta-lactamase_625_E145G,beta-lactamase_625_145,TEM-1,beta-lactamase_625,P62593,1.00478,NO,145,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.357,-1.279,-1.078,,0.545,H,A,1.04,0.79,2.64,,77.62,BAH,-2.069,0.213352,0.00553285,1.00478 beta-lactamase_156_G85F,beta-lactamase_156_85,TEM-1,beta-lactamase_156,P62593,1.00479,NO,85,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.011,-4.377,3.366,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.111618,0.00252173,1.00479 beta-lactamase_625_G216C,beta-lactamase_625_216,TEM-1,beta-lactamase_625,P62593,1.00479,NO,216,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.477,-5.186,3.709,,0.437,I,A,0.29,-0.58,1.718,,74.48,HOO,-1.68067,0.213352,0.00639568,1.00479 beta-lactamase_625_S57K,beta-lactamase_625_57,TEM-1,beta-lactamase_625,P62593,1.00479,NO,57,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.918,-3.565,1.647,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.213352,0.00492804,1.00479 beta-lactamase_625_Y103H,beta-lactamase_625_103,TEM-1,beta-lactamase_625,P62593,1.00479,NO,103,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-1.33,-2.243,0.913,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.213352,0.00443048,1.00479 beta-lactamase_625_G90A,beta-lactamase_625_90,TEM-1,beta-lactamase_625,P62593,1.0048,NO,90,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-2.091,-2.713,0.622,,0.598,T,A,0.29,0.32,0.319,,77.62,HOB,-1.52633,0.213352,0.00490273,1.0048 beta-lactamase_156_E62M,beta-lactamase_156_62,TEM-1,beta-lactamase_156,P62593,1.00481,NO,62,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.193,-4.77,3.577,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.111618,0.00264802,1.00481 beta-lactamase_156_L79M,beta-lactamase_156_79,TEM-1,beta-lactamase_156,P62593,1.00481,NO,79,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.842,-2.761,1.919,,0.007,H,A,0.55,-0.16,1.831,,50.35,HHP,-1.44333,0.111618,0.000947397,1.00481 beta-lactamase_39_K286W,beta-lactamase_39_286,TEM-1,beta-lactamase_39,P62593,1.00481,NO,286,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.111,-3.724,2.613,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.0495842,,1.00481 beta-lactamase_625_T193F,beta-lactamase_625_193,TEM-1,beta-lactamase_625,P62593,1.00481,NO,193,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.914,-2.368,0.454,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.213352,0.00482669,1.00481 beta-lactamase_156_A247I,beta-lactamase_156_247,TEM-1,beta-lactamase_156,P62593,1.00482,NO,247,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.111618,0.00611275,1.00482 beta-lactamase_39_L38W,beta-lactamase_39_38,TEM-1,beta-lactamase_39,P62593,1.00482,NO,38,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.343,-5.229,3.886,,0.088,H,A,0.55,0.2,17.089,17.089,64.34,PHO,-1.78033,0.0495842,0.00373244,1.00482 beta-lactamase_625_R273G,beta-lactamase_625_273,TEM-1,beta-lactamase_625,P62593,1.00482,NO,273,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.314,-2.465,0.151,,0.564,H,A,1.2,1.57,1.455,,73.78,ABP,-1.841,0.213352,0.0077952,1.00482 Pab1_E161I,Pab1_161,Pab1,Pab1,P04147,1.00482,NO,161,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.474,-3.893,2.419,,0.663,T,a,,1.34,,,,AAP,-1.59067,0.175299,0.00276141,1.00482 Pab1_N187K,Pab1_187,Pab1,Pab1,P04147,1.00482,NO,187,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-1.224,-3.153,1.929,,0.456,S,b,,1.87,,,,HPO,-1.272,0.175299,0.00083165,1.00482 beta-lactamase_156_F70T,beta-lactamase_156_70,TEM-1,beta-lactamase_156,P62593,1.00483,NO,70,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.169,-3.571,2.402,,,H,A,0.58,-1.34,1.918,,63.99,PHB,-0.980667,0.111618,0.00193499,1.00483 beta-lactamase_156_G281L,beta-lactamase_156_281,TEM-1,beta-lactamase_156,P62593,1.00483,NO,281,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.111618,0.0406482,1.00483 beta-lactamase_156_T126K,beta-lactamase_156_126,TEM-1,beta-lactamase_156,P62593,1.00483,NO,126,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.122,-3.536,2.414,,0.05,H,A,0.22,-0.05,1.14,,44.41,HPH,-1.60467,0.111618,0.00244552,1.00483 beta-lactamase_625_H287Q,beta-lactamase_625_287,TEM-1,beta-lactamase_625,P62593,1.00483,NO,287,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,,,,,,,,,,,,,BBH,-1.111,0.213352,,1.00483 beta-lactamase_156_E61N,beta-lactamase_156_61,TEM-1,beta-lactamase_156,P62593,1.00484,NO,61,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.115,-2.373,0.258,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.111618,0.00440955,1.00484 beta-lactamase_2500_Q88R,beta-lactamase_2500_88,TEM-1,beta-lactamase_2500,P62593,1.00484,NO,88,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.086,-2.458,0.372,,0.807,,B,0.64,2.03,1.84,,77.62,APH,-1.53433,0.361275,0.00504167,1.00484 beta-lactamase_39_R242S,beta-lactamase_39_242,TEM-1,beta-lactamase_39,P62593,1.00484,NO,242,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.0495842,0.00452879,1.00484 beta-lactamase_625_N168D,beta-lactamase_625_168,TEM-1,beta-lactamase_625,P62593,1.00484,NO,168,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-1.029,-3.143,2.114,,0.113,G,A,0.61,-0.4,1.014,,44.41,HPA,-1.13233,0.213352,0.00288667,1.00484 beta-lactamase_625_N50G,beta-lactamase_625_50,TEM-1,beta-lactamase_625,P62593,1.00484,NO,50,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-2.979,-2.053,-0.926,,0.912,T,A,0.61,1.24,3.446,,77.62,HPP,-2.134,0.213352,0.0047211,1.00484 beta-lactamase_625_R239C,beta-lactamase_625_239,TEM-1,beta-lactamase_625,P62593,1.00484,NO,239,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.213352,0.00213852,1.00484 beta-lactamase_625_R59K,beta-lactamase_625_59,TEM-1,beta-lactamase_625,P62593,1.00484,NO,59,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.345,-2.351,1.006,,0.329,S,L,1.2,-0.09,2.995,,73.08,HBO,-2.24267,0.213352,0.00318082,1.00484 beta-lactamase_E166I,beta-lactamase_166,TEM-1,beta-lactamase,P62593,1.00484,NO,166,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.756,-3.874,2.118,5.60527,0.508,G,A,0.52,1.05,2.124,,73.08,OAH,-1.42233,0.221079,0.00512989,1.00484 beta-lactamase_F228Y,beta-lactamase_228,TEM-1,beta-lactamase,P62593,1.00484,NO,228,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-2.342,-4.005,1.663,5.33448,0.154,E,B,1.1,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.221079,0.0046669,1.00484 beta-lactamase_G90T,beta-lactamase_90,TEM-1,beta-lactamase,P62593,1.00484,NO,90,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-2.091,-2.913,0.822,5.51991,0.598,T,A,0.23,0.32,1.791,,77.62,HOB,-1.52633,0.221079,0.00490273,1.00484 beta-lactamase_L111I,beta-lactamase_111,TEM-1,beta-lactamase,P62593,1.00484,NO,111,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.76,-2.153,0.393,5.8705,0.328,T,A,0.84,0.93,3.836,,64.34,BHP,-1.884,0.221079,0.00480671,1.00484 beta-lactamase_156_D174Q,beta-lactamase_156_174,TEM-1,beta-lactamase_156,P62593,1.00485,NO,174,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.738,-3.674,2.936,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.111618,0.00125633,1.00485 beta-lactamase_625_I93V,beta-lactamase_625_93,TEM-1,beta-lactamase_625,P62593,1.00485,NO,93,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.401,-1.692,0.291,,0.128,E,B,0.48,0.44,1.524,,67.83,BHB,-1.873,0.213352,0.00527066,1.00485 beta-lactamase_2500_E102A,beta-lactamase_2500_102,TEM-1,beta-lactamase_2500,P62593,1.00486,NO,102,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.118,-2.327,0.209,,0.722,S,B,1.04,1.82,1.336,,73.08,HAH,-1.581,0.361275,0.00486633,1.00486 beta-lactamase_39_N50S,beta-lactamase_39_50,TEM-1,beta-lactamase_39,P62593,1.00486,NO,50,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-2.979,-3.331,0.352,,0.912,T,A,0.61,1.24,10.736,,77.62,HPP,-2.134,0.0495842,0.0047211,1.00486 beta-lactamase_156_T131G,beta-lactamase_156_131,TEM-1,beta-lactamase_156,P62593,1.00487,NO,131,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.328,-3.298,1.97,,,H,A,0.22,-0.69,2.031,,67.48,PPH,-1.00867,0.111618,0.00345886,1.00487 beta-lactamase_2500_Q86S,beta-lactamase_2500_86,TEM-1,beta-lactamase_2500,P62593,1.00487,NO,86,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.4,-2.711,0.311,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.361275,0.00450027,1.00487 beta-lactamase_39_R242F,beta-lactamase_39_242,TEM-1,beta-lactamase_39,P62593,1.00487,NO,242,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.0495842,0.00452879,1.00487 beta-lactamase_625_A278H,beta-lactamase_625_278,TEM-1,beta-lactamase_625,P62593,1.00487,NO,278,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.213352,0.0310297,1.00487 beta-lactamase_625_P105L,beta-lactamase_625_105,TEM-1,beta-lactamase_625,P62593,1.00487,NO,105,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.813,-3.581,2.768,,0.226,T,A,0.52,0.8,1.154,,63.29,POH,-1.01533,0.213352,0.0011981,1.00487 beta-lactamase_625_T27A,beta-lactamase_625_27,TEM-1,beta-lactamase_625,P62593,1.00487,NO,27,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.905,-2.5,0.595,,0.007,H,A,0.22,-0.37,3.72,,93.01,APH,-1.97933,0.213352,0.00306559,1.00487 beta-lactamase_T178T,beta-lactamase_178,TEM-1,beta-lactamase,P62593,1.00487,NO,178,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-0.791,-0.791,,5.06452,0.029,E,B,0.3,-1.07,,,,APP,-0.947667,0.221079,0.000684366,1.00487 beta-lactamase_0_L160S,beta-lactamase_0_160,TEM-1,beta-lactamase_0,P62593,1.00488,NO,160,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.977,-3.653,2.676,,0.022,,B,0.55,-0.6,0.68,,44.41,BHA,-0.936,0.0500837,0.00193775,1.00488 beta-lactamase_156_S221A,beta-lactamase_156_221,TEM-1,beta-lactamase_156,P62593,1.00488,NO,221,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.754,-1.332,-0.422,,0.624,H,A,0.27,-0.2,17.729,17.729,74.48,BPH,-1.59967,0.111618,0.0046094,1.00488 beta-lactamase_2500_Q267T,beta-lactamase_2500_267,TEM-1,beta-lactamase_2500,P62593,1.00488,NO,267,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.308,-3.09,0.782,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.361275,0.0102128,1.00488 beta-lactamase_39_R81L,beta-lactamase_39_81,TEM-1,beta-lactamase_39,P62593,1.00488,NO,81,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.466,-2.766,1.3,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.0495842,0.00499763,1.00488 beta-lactamase_625_G90I,beta-lactamase_625_90,TEM-1,beta-lactamase_625,P62593,1.00488,NO,90,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-2.091,-4.052,1.961,,0.598,T,A,0.29,0.32,0.319,,77.62,HOB,-1.52633,0.213352,0.00490273,1.00488 beta-lactamase_156_K30L,beta-lactamase_156_30,TEM-1,beta-lactamase_156,P62593,1.00489,NO,30,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-2.307,-3.404,1.097,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.111618,0.00448593,1.00489 beta-lactamase_39_M270H,beta-lactamase_39_270,TEM-1,beta-lactamase_39,P62593,1.00489,NO,270,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.0495842,0.00767762,1.00489 beta-lactamase_156_L135F,beta-lactamase_156_135,TEM-1,beta-lactamase_156,P62593,1.0049,NO,135,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.002,-3.671,2.669,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.111618,0.00244423,1.0049 beta-lactamase_156_L191V,beta-lactamase_156_191,TEM-1,beta-lactamase_156,P62593,1.0049,NO,191,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.087,-2.22,1.133,,,H,A,0.55,0.09,1.372,,63.29,BHH,-1.445,0.111618,0.00263549,1.0049 beta-lactamase_39_F70Q,beta-lactamase_39_70,TEM-1,beta-lactamase_39,P62593,1.0049,NO,70,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.169,-4.201,3.032,,,H,A,0.58,-1.34,1.14,,63.99,PHB,-0.980667,0.0495842,0.00193499,1.0049 beta-lactamase_156_E272Y,beta-lactamase_156_272,TEM-1,beta-lactamase_156,P62593,1.00491,NO,272,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.111618,0.00545371,1.00491 beta-lactamase_156_Q86S,beta-lactamase_156_86,TEM-1,beta-lactamase_156,P62593,1.00491,NO,86,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.4,-2.711,0.311,,0.696,S,A,0.64,2.38,27.704,27.704,77.62,OPA,-1.61067,0.111618,0.00450027,1.00491 beta-lactamase_625_G90E,beta-lactamase_625_90,TEM-1,beta-lactamase_625,P62593,1.00491,NO,90,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-2.091,-2.175,0.084,,0.598,T,A,0.29,0.32,0.319,,77.62,HOB,-1.52633,0.213352,0.00490273,1.00491 beta-lactamase_0_I277T,beta-lactamase_0_277,TEM-1,beta-lactamase_0,P62593,1.00492,NO,277,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.0500837,0.0169305,1.00492 beta-lactamase_156_H156Y,beta-lactamase_156_156,TEM-1,beta-lactamase_156,P62593,1.00492,NO,156,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-3.156,-4.359,1.203,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.111618,0.00468596,1.00492 beta-lactamase_2500_A183V,beta-lactamase_2500_183,TEM-1,beta-lactamase_2500,P62593,1.00492,NO,183,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.231,-3.28,2.049,,0.155,H,A,0.46,-0.91,12.189,,77.62,HHH,-1.53367,0.361275,0.00296631,1.00492 beta-lactamase_2500_F149Y,beta-lactamase_2500_149,TEM-1,beta-lactamase_2500,P62593,1.00492,NO,149,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.299,-1.705,0.406,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.361275,0.00418462,1.00492 hsp90_Q582V,hsp90_582,hsp90,hsp90,P02829,1.00492,NO,582,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-3.278,-2.682,0,4.91603,0.453,S,B,,0.67,,,,OPH,-3.249,0.368192,0.000222939,1.00492 beta-lactamase_0_V101C,beta-lactamase_0_101,TEM-1,beta-lactamase_0,P62593,1.00493,NO,101,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.295,-4.837,3.542,,0.342,,B,0.44,0,1.61,,73.08,HHA,-1.54367,0.0500837,0.00374492,1.00493 beta-lactamase_156_R202Q,beta-lactamase_156_202,TEM-1,beta-lactamase_156,P62593,1.00493,NO,202,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.292,-1.95,0.658,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.111618,0.00321899,1.00493 beta-lactamase_2500_H151T,beta-lactamase_2500_151,TEM-1,beta-lactamase_2500,P62593,1.00493,NO,151,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-2.96,-3.492,0.532,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.361275,0.00216946,1.00493 beta-lactamase_39_D212L,beta-lactamase_39_212,TEM-1,beta-lactamase_39,P62593,1.00493,NO,212,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.624,-3.598,1.974,,0.037,,b,0.75,-0.58,10.748,10.748,74.48,HAB,-1.77667,0.0495842,0.00644302,1.00493 beta-lactamase_39_D99E,beta-lactamase_39_99,TEM-1,beta-lactamase_39,P62593,1.00493,NO,99,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.191,-2.122,0.931,,0.402,G,A,0.75,0.36,0.374,,64.69,PAH,-1.794,0.0495842,0.00305446,1.00493 Pab1_D184Q,Pab1_184,Pab1,Pab1,P04147,1.00493,NO,184,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.5,-3.288,1.788,,,,,,,,,,HAH,-1.50133,0.175299,0.0011931,1.00493 beta-lactamase_39_F70S,beta-lactamase_39_70,TEM-1,beta-lactamase_39,P62593,1.00494,NO,70,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.169,-2.713,1.544,,,H,A,0.58,-1.34,1.14,,63.99,PHB,-0.980667,0.0495842,0.00193499,1.00494 beta-lactamase_39_L47Q,beta-lactamase_39_47,TEM-1,beta-lactamase_39,P62593,1.00494,NO,47,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.876,-3.17,1.294,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.0495842,0.00439844,1.00494 beta-lactamase_39_R257Q,beta-lactamase_39_257,TEM-1,beta-lactamase_39,P62593,1.00494,NO,257,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.0495842,0.00756629,1.00494 beta-lactamase_156_P65S,beta-lactamase_156_65,TEM-1,beta-lactamase_156,P62593,1.00495,NO,65,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.894,-3.44,2.546,,0.098,E,B,0.52,-0.62,0.623,,40.56,HOH,-1.03233,0.111618,0.00152776,1.00495 beta-lactamase_39_D99M,beta-lactamase_39_99,TEM-1,beta-lactamase_39,P62593,1.00495,NO,99,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.191,-3.198,2.007,,0.402,G,A,0.75,0.36,0.374,,64.69,PAH,-1.794,0.0495842,0.00305446,1.00495 beta-lactamase_39_R159S,beta-lactamase_39_159,TEM-1,beta-lactamase_39,P62593,1.00495,NO,159,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-0.94,-3.411,2.471,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.0495842,0.00108472,1.00495 PSD95pdz3_R313F,PSD95pdz3_313,PSD95pdz3,PSD95pdz3,P31016,1.00495,NO,313,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.582,-3.974,2.392,6.63563,,,,,18.3955,,,,BBH,-1.59733,0.0758425,0.000840067,1.00495 beta-lactamase_156_H287A,beta-lactamase_156_287,TEM-1,beta-lactamase_156,P62593,1.00496,NO,287,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,,,,,,,,,,,,,BBH,-1.111,0.111618,,1.00496 beta-lactamase_156_Q97G,beta-lactamase_156_97,TEM-1,beta-lactamase_156,P62593,1.00496,NO,97,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.072,-2.827,0.755,,0.823,G,A,0.64,2.42,4.457,,77.62,PPP,-2.43833,0.111618,0.0045116,1.00496 beta-lactamase_39_P105A,beta-lactamase_39_105,TEM-1,beta-lactamase_39,P62593,1.00496,NO,105,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.813,-3.041,2.228,,0.226,T,A,0.52,0.8,1.222,,63.29,POH,-1.01533,0.0495842,0.0011981,1.00496 beta-lactamase_39_S201E,beta-lactamase_39_201,TEM-1,beta-lactamase_39,P62593,1.00497,NO,201,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.183,-3.352,2.169,,0.064,H,A,0.27,-0.07,3.54,,64.69,HPB,-1.451,0.0495842,0.00198815,1.00497 beta-lactamase_0_L205I,beta-lactamase_0_205,TEM-1,beta-lactamase_0,P62593,1.00498,NO,205,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.922,-2.97,2.048,,,H,A,0.55,-0.46,1.065,,42.31,PHH,-1.57767,0.0500837,0.00255802,1.00498 beta-lactamase_39_T138V,beta-lactamase_39_138,TEM-1,beta-lactamase_39,P62593,1.00498,NO,138,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.506,-3.689,1.183,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.0495842,0.00487868,1.00498 beta-lactamase_156_P143Q,beta-lactamase_156_143,TEM-1,beta-lactamase_156,P62593,1.00499,NO,143,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.967,-4.024,3.057,,0.075,H,A,0.52,-0.37,0.479,,66.78,OOB,-1.354,0.111618,0.00114551,1.00499 beta-lactamase_2500_S283A,beta-lactamase_2500_283,TEM-1,beta-lactamase_2500,P62593,1.00499,NO,283,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.361275,0.0429138,1.00499 beta-lactamase_39_A235Y,beta-lactamase_39_235,TEM-1,beta-lactamase_39,P62593,1.00499,NO,235,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.266,-4.294,3.028,,0.32,E,B,0.46,-0.86,1.344,,50,OHO,-0.89,0.0495842,0.00493474,1.00499 beta-lactamase_Q37R,beta-lactamase_37,TEM-1,beta-lactamase,P62593,1.00499,NO,37,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.134,-2.096,-0.038,5.69153,0.613,H,A,0.12,1.98,1.318,,73.08,APH,-2.06967,0.221079,0.00425833,1.00499 PSD95pdz3_S371H,PSD95pdz3_371,PSD95pdz3,PSD95pdz3,P31016,1.00499,NO,371,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.86,-4.361,2.501,5.19744,,,,,17.1117,3.854,,87.71,HPB,-1.598,0.0758425,0.000847873,1.00499 beta-lactamase_156_D48C,beta-lactamase_156_48,TEM-1,beta-lactamase_156,P62593,1.005,NO,48,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.101,-5.125,4.024,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.111618,0.0027273,1.005 beta-lactamase_156_T131C,beta-lactamase_156_131,TEM-1,beta-lactamase_156,P62593,1.005,NO,131,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.328,-3.123,1.795,,,H,A,0.22,-0.69,2.031,,67.48,PPH,-1.00867,0.111618,0.00345886,1.005 beta-lactamase_2500_A84R,beta-lactamase_2500_84,TEM-1,beta-lactamase_2500,P62593,1.005,NO,84,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.651,-2.603,0.952,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.361275,0.00503822,1.005 beta-lactamase_625_I258L,beta-lactamase_625_258,TEM-1,beta-lactamase_625,P62593,1.005,NO,258,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.213352,0.007931,1.005 beta-lactamase_625_M115I,beta-lactamase_625_115,TEM-1,beta-lactamase_625,P62593,1.00501,NO,115,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.389,-3.258,1.869,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.213352,0.0034337,1.00501 beta-lactamase_625_T186P,beta-lactamase_625_186,TEM-1,beta-lactamase_625,P62593,1.00501,NO,186,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.522,-3.945,1.423,,0.396,H,A,0.22,-0.28,0.515,,77.62,HPP,-1.77633,0.213352,0.00485034,1.00501 beta-lactamase_R118C,beta-lactamase_118,TEM-1,beta-lactamase,P62593,1.00501,NO,118,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.413,-4.992,2.579,5.8227,0.457,H,A,0.68,1.39,2.144,,77.62,HBA,-1.785,0.221079,0.00538794,1.00501 beta-lactamase_156_R159W,beta-lactamase_156_159,TEM-1,beta-lactamase_156,P62593,1.00502,NO,159,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-0.94,-5.32,4.38,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.111618,0.00108472,1.00502 beta-lactamase_39_K286R,beta-lactamase_39_286,TEM-1,beta-lactamase_39,P62593,1.00502,NO,286,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.0495842,,1.00502 beta-lactamase_625_A268S,beta-lactamase_625_268,TEM-1,beta-lactamase_625,P62593,1.00502,NO,268,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.213352,0.0102525,1.00502 beta-lactamase_156_Q276N,beta-lactamase_156_276,TEM-1,beta-lactamase_156,P62593,1.00503,NO,276,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.111618,0.0191712,1.00503 beta-lactamase_156_T264A,beta-lactamase_156_264,TEM-1,beta-lactamase_156,P62593,1.00503,NO,264,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.111618,0.0119399,1.00503 beta-lactamase_156_V82Q,beta-lactamase_156_82,TEM-1,beta-lactamase_156,P62593,1.00503,NO,82,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.325,-4.196,2.871,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.111618,0.00397046,1.00503 beta-lactamase_39_E166I,beta-lactamase_39_166,TEM-1,beta-lactamase_39,P62593,1.00503,NO,166,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.756,-3.874,2.118,,0.508,G,A,1.04,1.05,17.227,17.227,73.08,OAH,-1.42233,0.0495842,0.00512989,1.00503 beta-lactamase_39_S96E,beta-lactamase_39_96,TEM-1,beta-lactamase_39,P62593,1.00503,NO,96,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.27,-2.567,0.297,,0.368,,b,0.27,0.39,2.516,,73.78,HPP,-2.019,0.0495842,0.00551835,1.00503 beta-lactamase_0_L137V,beta-lactamase_0_137,TEM-1,beta-lactamase_0,P62593,1.00504,NO,137,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.03,-2.816,1.786,,,H,A,0.55,-0.38,0.328,,42.31,HHP,-1.58933,0.0500837,0.00278599,1.00504 beta-lactamase_625_S283I,beta-lactamase_625_283,TEM-1,beta-lactamase_625,P62593,1.00504,NO,283,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.638,-3.539,1.901,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.213352,0.0429138,1.00504 beta-lactamase_625_T186H,beta-lactamase_625_186,TEM-1,beta-lactamase_625,P62593,1.00504,NO,186,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.522,-4.717,2.195,,0.396,H,A,0.22,-0.28,0.515,,77.62,HPP,-1.77633,0.213352,0.00485034,1.00504 beta-lactamase_156_L137V,beta-lactamase_156_137,TEM-1,beta-lactamase_156,P62593,1.00505,NO,137,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.03,-2.816,1.786,,,H,A,0.55,-0.38,0.674,,42.31,HHP,-1.58933,0.111618,0.00278599,1.00505 beta-lactamase_156_L160F,beta-lactamase_156_160,TEM-1,beta-lactamase_156,P62593,1.00505,NO,160,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.977,-3.681,2.704,,0.022,,B,0.55,-0.6,1.095,,44.41,BHA,-0.936,0.111618,0.00193775,1.00505 beta-lactamase_156_Q37E,beta-lactamase_156_37,TEM-1,beta-lactamase_156,P62593,1.00505,NO,37,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.134,-2.427,0.293,,0.613,H,A,0.64,1.98,12.052,12.052,73.08,APH,-2.06967,0.111618,0.00425833,1.00505 beta-lactamase_39_V260C,beta-lactamase_39_260,TEM-1,beta-lactamase_39,P62593,1.00505,NO,260,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.0495842,0.00471757,1.00505 beta-lactamase_625_I244L,beta-lactamase_625_244,TEM-1,beta-lactamase_625,P62593,1.00505,NO,244,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.555,-2.697,1.142,,,E,B,0.48,-0.84,2.061,,77.62,OHH,-1.385,0.213352,0.00605379,1.00505 beta-lactamase_625_L73M,beta-lactamase_625_73,TEM-1,beta-lactamase_625,P62593,1.00505,NO,73,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.507,-2.898,1.391,,,H,A,0.55,-0.64,2.933,,67.83,HHH,-1.487,0.213352,0.00488983,1.00505 beta-lactamase_M153A,beta-lactamase_153,TEM-1,beta-lactamase,P62593,1.00505,NO,153,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-3.193,-2.415,-0.778,5.46509,0.14,T,A,1.07,-0.11,2.061,,77.62,PHO,-2.25767,0.221079,0.00509109,1.00505 Pab1_D160D,Pab1_160,Pab1,Pab1,P04147,1.00505,NO,160,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.985,-0.985,,,0.396,B,B,,1.12,,,,PAA,-1.30133,0.175299,0.000311977,1.00505 beta-lactamase_0_N173C,beta-lactamase_0_173,TEM-1,beta-lactamase_0,P62593,1.00506,NO,173,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-2.663,-5.092,2.429,,1.044,T,l,0.61,1.25,1.133,,77.62,OPA,-1.46633,0.0500837,0.0033769,1.00506 beta-lactamase_2500_N173Y,beta-lactamase_2500_173,TEM-1,beta-lactamase_2500,P62593,1.00506,NO,173,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-2.663,-4.409,1.746,,1.044,T,l,0.61,1.25,1.88,,77.62,OPA,-1.46633,0.361275,0.0033769,1.00506 beta-lactamase_2500_Q276V,beta-lactamase_2500_276,TEM-1,beta-lactamase_2500,P62593,1.00506,NO,276,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.361275,0.0191712,1.00506 beta-lactamase_156_M180G,beta-lactamase_156_180,TEM-1,beta-lactamase_156,P62593,1.00507,NO,180,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-2.795,-3.389,0.594,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.111618,0.00552048,1.00507 beta-lactamase_39_A123S,beta-lactamase_39_123,TEM-1,beta-lactamase_39,P62593,1.00507,NO,123,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.834,-3.019,2.185,,0.039,H,A,0.46,-0.72,0.705,,41.26,PHH,-1.47367,0.0495842,0.0010157,1.00507 gb1_D262Y,gb1_262,gb1,gb1,P06654,1.00507,NO,262,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-3.132,-4.072,0.94,,,,,,,1.304,,45.54,PAP,-2.05233,0.177985,0.00413102,1.00507 beta-lactamase_156_K190G,beta-lactamase_156_190,TEM-1,beta-lactamase_156,P62593,1.00508,NO,190,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.994,-3.44,1.446,,0.371,H,A,2.34,0.16,1.513,,77.62,BBH,-1.64167,0.111618,0.00574527,1.00508 beta-lactamase_156_V117T,beta-lactamase_156_117,TEM-1,beta-lactamase_156,P62593,1.00508,NO,117,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.53,-3.486,1.956,,,H,A,0.44,-0.34,1.182,,65.03,PHB,-1.741,0.111618,0.00467906,1.00508 beta-lactamase_39_K144F,beta-lactamase_39_144,TEM-1,beta-lactamase_39,P62593,1.00509,NO,144,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-2.388,-4.427,2.039,,0.863,H,A,2.34,1.27,14.556,14.556,77.62,OBA,-1.904,0.0495842,0.00481141,1.00509 beta-lactamase_39_V259A,beta-lactamase_39_259,TEM-1,beta-lactamase_39,P62593,1.00509,NO,259,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.0495842,0.0070773,1.00509 beta-lactamase_625_P105V,beta-lactamase_625_105,TEM-1,beta-lactamase_625,P62593,1.00509,NO,105,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.813,-3.554,2.741,,0.226,T,A,0.52,0.8,1.154,,63.29,POH,-1.01533,0.213352,0.0011981,1.00509 kka2_1:8_E199G,kka2_1:8_199,Kka2,kka2_1:8,P00552,1.00509,NO,199,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.234,-3.518,1.284,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.100394,0.00854122,1.00509 kka2_1:8_E199G,kka2_1:8_199,Kka2,kka2_1:8,P00552,1.00509,NO,199,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.234,-3.518,1.284,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.100394,0.00854122,1.00509 PSD95pdz3_K380T,PSD95pdz3_380,PSD95pdz3,PSD95pdz3,P31016,1.00509,NO,380,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.416,-3.103,1.687,5.87979,,,,,19.6722,,,,HBP,-1.391,0.0758425,0.000281399,1.00509 beta-lactamase_156_A282D,beta-lactamase_156_282,TEM-1,beta-lactamase_156,P62593,1.0051,NO,282,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.111618,0.0449821,1.0051 beta-lactamase_39_L55T,beta-lactamase_39_55,TEM-1,beta-lactamase_39,P62593,1.0051,NO,55,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.86,-3.617,1.757,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.0495842,0.00403741,1.0051 beta-lactamase_39_S241H,beta-lactamase_39_241,TEM-1,beta-lactamase_39,P62593,1.00511,NO,241,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.0495842,0.00452736,1.00511 kka2_1:4_L19C,kka2_1:4_19,Kka2,kka2_1:4,P00552,1.00511,NO,19,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.254,-4.888,3.634,,0.08,T,A,1.59,-0.26,2.645,,65.53,BHH,-2.221,0.168804,0.00620703,1.00511 beta-lactamase_156_D271V,beta-lactamase_156_271,TEM-1,beta-lactamase_156,P62593,1.00512,NO,271,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.111618,0.00752082,1.00512 beta-lactamase_625_I140T,beta-lactamase_625_140,TEM-1,beta-lactamase_625,P62593,1.00512,NO,140,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.733,-2.748,1.015,,0.128,H,A,0.48,0.41,1.628,,73.08,PHO,-1.48733,0.213352,0.00597777,1.00512 PSD95pdz3_G351R,PSD95pdz3_351,PSD95pdz3,PSD95pdz3,P31016,1.00512,NO,351,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.008,-3.615,2.607,5.44798,,,,,20.7625,,,,POA,-1.37133,0.0758425,0.000691282,1.00512 beta-lactamase_0_A182P,beta-lactamase_0_182,TEM-1,beta-lactamase_0,P62593,1.00513,NO,182,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.777,-3.952,2.175,,0.136,H,A,0.46,-0.66,10.765,10.765,93.01,OHH,-1.27367,0.0500837,0.00559099,1.00513 beta-lactamase_156_E62G,beta-lactamase_156_62,TEM-1,beta-lactamase_156,P62593,1.00513,NO,62,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.193,-2.548,1.355,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.111618,0.00264802,1.00513 beta-lactamase_156_R273C,beta-lactamase_156_273,TEM-1,beta-lactamase_156,P62593,1.00513,NO,273,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.314,-5.09,2.776,,0.564,H,A,1.2,1.57,20.248,20.248,73.78,ABP,-1.841,0.111618,0.0077952,1.00513 beta-lactamase_2500_G90N,beta-lactamase_2500_90,TEM-1,beta-lactamase_2500,P62593,1.00513,NO,90,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-2.091,-2.941,0.85,,0.598,T,A,0.29,0.32,1.2,,77.62,HOB,-1.52633,0.361275,0.00490273,1.00513 beta-lactamase_39_D174M,beta-lactamase_39_174,TEM-1,beta-lactamase_39,P62593,1.00513,NO,174,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.738,-4.93,4.192,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.0495842,0.00125633,1.00513 beta-lactamase_A148C,beta-lactamase_148,TEM-1,beta-lactamase,P62593,1.00513,NO,148,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.757,-5.042,3.285,5.28111,0.379,H,A,0.52,-0.55,2.117,,72.73,PHH,-1.40167,0.221079,0.00547053,1.00513 beta-lactamase_A222I,beta-lactamase_222,TEM-1,beta-lactamase,P62593,1.00513,NO,222,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.103,-3.632,1.529,5.2262,0.233,H,A,0.47,-0.25,0.379,,77.62,PHH,-1.63733,0.221079,0.00466094,1.00513 beta-lactamase_156_Q37P,beta-lactamase_156_37,TEM-1,beta-lactamase_156,P62593,1.00514,NO,37,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.134,-3.965,1.831,,0.613,H,A,0.64,1.98,12.052,12.052,73.08,APH,-2.06967,0.111618,0.00425833,1.00514 beta-lactamase_39_G114M,beta-lactamase_39_114,TEM-1,beta-lactamase_39,P62593,1.00514,NO,114,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.094,-4.83,3.736,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.0495842,0.00224919,1.00514 beta-lactamase_625_H156W,beta-lactamase_625_156,TEM-1,beta-lactamase_625,P62593,1.00514,NO,156,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-3.156,-5.55,2.394,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.213352,0.00468596,1.00514 beta-lactamase_2500_L28I,beta-lactamase_2500_28,TEM-1,beta-lactamase_2500,P62593,1.00515,NO,28,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.579,-2.204,0.625,,0.277,H,A,0.55,-0.16,2.716,,93.01,PHH,-2.11333,0.361275,0.00359321,1.00515 beta-lactamase_625_A84F,beta-lactamase_625_84,TEM-1,beta-lactamase_625,P62593,1.00515,NO,84,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.651,-4.366,2.715,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.213352,0.00503822,1.00515 beta-lactamase_156_P60L,beta-lactamase_156_60,TEM-1,beta-lactamase_156,P62593,1.00516,NO,60,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-2.469,-2.818,0.349,,0.256,T,A,0.52,-0.56,2.947,,77.62,BOA,-1.97633,0.111618,0.00521318,1.00516 beta-lactamase_156_V106W,beta-lactamase_156_106,TEM-1,beta-lactamase_156,P62593,1.00516,NO,106,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.218,-5.22,4.002,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.111618,0.00304168,1.00516 beta-lactamase_E237D,beta-lactamase_237,TEM-1,beta-lactamase,P62593,1.00516,NO,237,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.058,-2.484,0.426,5.42877,0.583,S,B,1.62,1.2,2.144,,77.62,OAB,-1.61467,0.221079,0.0048626,1.00516 beta-lactamase_39_K109V,beta-lactamase_39_109,TEM-1,beta-lactamase_39,P62593,1.00517,NO,109,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.734,-3.727,1.993,,0.787,G,A,2.34,2.21,7.243,,72.73,ABB,-1.63333,0.0495842,0.00462493,1.00517 beta-lactamase_39_L136A,beta-lactamase_39_136,TEM-1,beta-lactamase_39,P62593,1.00517,NO,136,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.232,-3.144,1.912,,,H,A,0.55,-0.34,0.336,,48.95,HHH,-1.088,0.0495842,0.00442304,1.00517 beta-lactamase_T267S,beta-lactamase_267,TEM-1,beta-lactamase,P62593,1.00517,NO,267,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.308,-1.8,-0.508,5.28263,0.54,,B,0.69,-0.14,0.374,,73.78,HPH,-1.9,0.221079,0.0102128,1.00517 beta-lactamase_156_R92G,beta-lactamase_156_92,TEM-1,beta-lactamase_156,P62593,1.00518,NO,92,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.718,-3.552,1.834,,0.479,E,B,1.2,1.36,19.112,19.112,65.38,BBH,-1.50367,0.111618,0.00429626,1.00518 beta-lactamase_39_Q267N,beta-lactamase_39_267,TEM-1,beta-lactamase_39,P62593,1.00518,NO,267,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.0495842,0.0102128,1.00518 beta-lactamase_39_V157A,beta-lactamase_39_157,TEM-1,beta-lactamase_39,P62593,1.00518,NO,157,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.751,-2.656,0.905,,0.308,S,a,0.44,-0.75,10.364,10.364,69.58,BHP,-2.00767,0.0495842,0.00506849,1.00518 PSD95pdz3_Q374G,PSD95pdz3_374,PSD95pdz3,PSD95pdz3,P31016,1.00518,NO,374,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-1.699,-3.04,1.341,5.38825,,,,,17.3289,,,,APH,-1.47,0.0758425,0.000372298,1.00518 WW_domain_D194V,WW_domain_194,Yap65,WW_domain,P46937,1.00518,NO,194,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.536,-3.268,1.732,5.95614,,,,,,1.948,,74.4,HAP,-1.78933,0.153962,0.00483742,1.00518 beta-lactamase_156_E195C,beta-lactamase_156_195,TEM-1,beta-lactamase_156,P62593,1.00519,NO,195,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.186,-5.238,3.052,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.111618,0.00496565,1.00519 beta-lactamase_2500_K109A,beta-lactamase_2500_109,TEM-1,beta-lactamase_2500,P62593,1.0052,NO,109,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.734,-3.283,1.549,,0.787,G,A,2.34,2.21,0.998,,72.73,ABB,-1.63333,0.361275,0.00462493,1.0052 beta-lactamase_39_L49M,beta-lactamase_39_49,TEM-1,beta-lactamase_39,P62593,1.0052,NO,49,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.897,-4.411,2.514,,0.131,T,A,0.55,0.04,13.838,13.838,64.69,AHP,-1.99233,0.0495842,0.00401477,1.0052 beta-lactamase_625_I280V,beta-lactamase_625_280,TEM-1,beta-lactamase_625,P62593,1.0052,NO,280,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.213352,0.0530888,1.0052 beta-lactamase_2500_A282E,beta-lactamase_2500_282,TEM-1,beta-lactamase_2500,P62593,1.00521,NO,282,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.361275,0.0449821,1.00521 beta-lactamase_625_A77H,beta-lactamase_625_77,TEM-1,beta-lactamase_625,P62593,1.00521,NO,77,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.234,-3.165,1.931,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.213352,0.00282362,1.00521 beta-lactamase_39_L167C,beta-lactamase_39_167,TEM-1,beta-lactamase_39,P62593,1.00522,NO,167,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.138,-4.763,3.625,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.0495842,0.00303566,1.00522 beta-lactamase_625_G265S,beta-lactamase_625_265,TEM-1,beta-lactamase_625,P62593,1.00522,NO,265,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.213352,0.00811926,1.00522 gb1_K236Y,gb1_236,gb1,gb1,P06654,1.00522,NO,236,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-2.119,-3.996,1.877,,,,,,,1.083,,45.54,OBP,-1.758,0.177985,0.00255408,1.00522 beta-lactamase_39_L73C,beta-lactamase_39_73,TEM-1,beta-lactamase_39,P62593,1.00523,NO,73,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.507,-4.861,3.354,,,H,A,0.55,-0.64,2.09,,67.83,HHH,-1.487,0.0495842,0.00488983,1.00523 beta-lactamase_39_R257F,beta-lactamase_39_257,TEM-1,beta-lactamase_39,P62593,1.00523,NO,257,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.0495842,0.00756629,1.00523 beta-lactamase_39_T198A,beta-lactamase_39_198,TEM-1,beta-lactamase_39,P62593,1.00523,NO,198,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.168,-2.502,0.334,,0.489,,B,0.22,-0.13,3.614,,73.78,HPH,-1.98767,0.0495842,0.004311,1.00523 beta-lactamase_625_M67N,beta-lactamase_625_67,TEM-1,beta-lactamase_625,P62593,1.00523,NO,67,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-2.231,-2.235,0.004,,0.006,G,P,0.55,-0.81,2.653,,65.03,HHP,-1.502,0.213352,0.00409753,1.00523 beta-lactamase_E277T,beta-lactamase_277,TEM-1,beta-lactamase,P62593,1.00523,NO,277,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.869,-2.877,1.008,5.51786,0.545,H,A,0.52,-0.01,2.022,,77.62,HAH,-1.45367,0.221079,0.0169305,1.00523 beta-lactamase_P25H,beta-lactamase_25,TEM-1,beta-lactamase,P62593,1.00523,NO,25,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.526,-4.604,3.078,5.6134,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.221079,0.00347571,1.00523 kka2_1:4_A150S,kka2_1:4_150,Kka2,kka2_1:4,P00552,1.00523,NO,150,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.949,-3.097,2.148,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.168804,0.0045009,1.00523 beta-lactamase_2500_E238H,beta-lactamase_2500_238,TEM-1,beta-lactamase_2500,P62593,1.00524,NO,238,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.361275,0.00743256,1.00524 beta-lactamase_2500_S51N,beta-lactamase_2500_51,TEM-1,beta-lactamase_2500,P62593,1.00524,NO,51,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.526,-2.556,1.03,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.361275,0.00504821,1.00524 beta-lactamase_39_K32H,beta-lactamase_39_32,TEM-1,beta-lactamase_39,P62593,1.00524,NO,32,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.984,-4.632,2.648,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.0495842,0.00401283,1.00524 beta-lactamase_156_E238P,beta-lactamase_156_238,TEM-1,beta-lactamase_156,P62593,1.00525,NO,238,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.111618,0.00743256,1.00525 beta-lactamase_156_K144Y,beta-lactamase_156_144,TEM-1,beta-lactamase_156,P62593,1.00525,NO,144,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-2.388,-4.321,1.933,,0.863,H,A,2.34,1.27,2.073,,77.62,OBA,-1.904,0.111618,0.00481141,1.00525 beta-lactamase_156_Q203M,beta-lactamase_156_203,TEM-1,beta-lactamase_156,P62593,1.00525,NO,203,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.168,-4.659,2.491,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.111618,0.00631514,1.00525 beta-lactamase_156_S51E,beta-lactamase_156_51,TEM-1,beta-lactamase_156,P62593,1.00525,NO,51,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.526,-3.428,1.902,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.111618,0.00504821,1.00525 beta-lactamase_39_V31I,beta-lactamase_39_31,TEM-1,beta-lactamase_39,P62593,1.00525,NO,31,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.822,-1.838,0.016,,,H,A,0.44,-0.46,2.885,,73.78,BHB,-2.03767,0.0495842,0.00478065,1.00525 beta-lactamase_625_S51Y,beta-lactamase_625_51,TEM-1,beta-lactamase_625,P62593,1.00525,NO,51,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.526,-4.345,2.819,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.213352,0.00504821,1.00525 beta-lactamase_0_T131F,beta-lactamase_0_131,TEM-1,beta-lactamase_0,P62593,1.00526,NO,131,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.328,-4.204,2.876,,,H,A,0.22,-0.69,3.306,,67.48,PPH,-1.00867,0.0500837,0.00345886,1.00526 beta-lactamase_2500_E61D,beta-lactamase_2500_61,TEM-1,beta-lactamase_2500,P62593,1.00526,NO,61,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.115,-1.402,-0.713,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.361275,0.00440955,1.00526 beta-lactamase_625_R59N,beta-lactamase_625_59,TEM-1,beta-lactamase_625,P62593,1.00526,NO,59,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.345,-2.533,1.188,,0.329,S,L,1.2,-0.09,2.995,,73.08,HBO,-2.24267,0.213352,0.00318082,1.00526 beta-lactamase_0_D36E,beta-lactamase_0_36,TEM-1,beta-lactamase_0,P62593,1.00527,NO,36,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.732,-2.66,-0.072,,0.555,H,A,0.75,1.17,13.689,13.689,77.62,AAP,-1.91167,0.0500837,0.00476483,1.00527 beta-lactamase_156_V42M,beta-lactamase_156_42,TEM-1,beta-lactamase_156,P62593,1.00527,NO,42,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.564,-2.813,1.249,,0.017,E,B,0.44,-0.51,2.576,,63.99,BHO,-1.042,0.111618,0.00404515,1.00527 beta-lactamase_39_A222R,beta-lactamase_39_222,TEM-1,beta-lactamase_39,P62593,1.00527,NO,222,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.103,-4.005,1.902,,0.233,H,A,0.46,-0.25,1.448,,77.62,PHH,-1.63733,0.0495842,0.00466094,1.00527 beta-lactamase_39_L167M,beta-lactamase_39_167,TEM-1,beta-lactamase_39,P62593,1.00527,NO,167,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.138,-2.673,1.535,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.0495842,0.00303566,1.00527 Pab1_Y143N,Pab1_143,Pab1,Pab1,P04147,1.00527,NO,143,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-1.961,-3.426,1.465,,0.409,H,A,,0.3,,,,HHA,-1.39633,0.175299,0.00160364,1.00527 beta-lactamase_156_G281C,beta-lactamase_156_281,TEM-1,beta-lactamase_156,P62593,1.00528,NO,281,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.111618,0.0406482,1.00528 beta-lactamase_156_N50W,beta-lactamase_156_50,TEM-1,beta-lactamase_156,P62593,1.00528,NO,50,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-2.979,-5.454,2.475,,0.912,T,A,0.61,1.24,13.295,13.295,77.62,HPP,-2.134,0.111618,0.0047211,1.00528 beta-lactamase_625_N173I,beta-lactamase_625_173,TEM-1,beta-lactamase_625,P62593,1.0053,NO,173,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-2.663,-4.172,1.509,,1.044,T,l,0.61,1.25,1.426,,77.62,OPA,-1.46633,0.213352,0.0033769,1.0053 beta-lactamase_E166N,beta-lactamase_166,TEM-1,beta-lactamase,P62593,1.0053,NO,166,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.756,-3.709,1.953,5.60527,0.508,G,A,0.52,1.05,2.124,,73.08,OAH,-1.42233,0.221079,0.00512989,1.0053 beta-lactamase_H24D,beta-lactamase_24,TEM-1,beta-lactamase,P62593,1.0053,NO,24,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-2.481,-2.42,-0.061,5.82767,,,,,,2.708,,93.01,HBO,-1.85167,0.221079,0.00238894,1.0053 beta-lactamase_K252M,beta-lactamase_252,TEM-1,beta-lactamase,P62593,1.0053,NO,252,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.94,-4.761,2.821,5.56823,0.766,,B,1.82,1.16,21.796,21.796,67.83,OBO,-2.03333,0.221079,0.00575769,1.0053 beta-lactamase_Q265F,beta-lactamase_265,TEM-1,beta-lactamase,P62593,1.0053,NO,265,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.58,-4.448,1.868,6.62674,1.116,,A,0.03,1.17,12.514,12.514,69.58,PPH,-1.978,0.221079,0.00811926,1.0053 beta-lactamase_Q274A,beta-lactamase_274,TEM-1,beta-lactamase,P62593,1.0053,NO,274,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.082,-1.482,-0.6,5.6671,0.066,H,A,0.11,-0.27,2.354,,64.69,BPH,-1.931,0.221079,0.0110418,1.0053 Pab1_T159V,Pab1_159,Pab1,Pab1,P04147,1.0053,NO,159,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.445,-3.067,1.622,,,,,,,2.531,,79.03,HPA,-1.19467,0.175299,0.00133849,1.0053 beta-lactamase_39_A230L,beta-lactamase_39_230,TEM-1,beta-lactamase_39,P62593,1.00531,NO,230,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.154,-3.416,2.262,,0.01,E,B,0.46,-1.17,1.171,,50,HHA,-1.079,0.0495842,0.00516841,1.00531 beta-lactamase_39_M127F,beta-lactamase_39_127,TEM-1,beta-lactamase_39,P62593,1.00531,NO,127,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-2.251,-3.969,1.718,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.0495842,0.00437927,1.00531 beta-lactamase_625_T138V,beta-lactamase_625_138,TEM-1,beta-lactamase_625,P62593,1.00531,NO,138,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.506,-3.689,1.183,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.213352,0.00487868,1.00531 kka2_1:8_Q27E,kka2_1:8_27,Kka2,kka2_1:8,P00552,1.00531,NO,27,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-1.659,-2.681,1.022,,0.608,.,A,0.64,0.71,3.919,,65.53,PPP,-1.90733,0.100394,0.00595365,1.00531 kka2_1:8_Q27E,kka2_1:8_27,Kka2,kka2_1:8,P00552,1.00531,NO,27,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-1.659,-2.681,1.022,,0.608,.,A,0.64,0.71,3.919,,65.53,PPP,-1.90733,0.100394,0.00595365,1.00531 beta-lactamase_156_E169A,beta-lactamase_156_169,TEM-1,beta-lactamase_156,P62593,1.00533,NO,169,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.23,-2.486,1.256,,0.337,,A,1.04,1,3.516,,73.08,PAH,-1.16533,0.111618,0.00400994,1.00533 beta-lactamase_156_L150H,beta-lactamase_156_150,TEM-1,beta-lactamase_156,P62593,1.00533,NO,150,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.326,-4.935,3.609,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.111618,0.00463171,1.00533 beta-lactamase_39_F70L,beta-lactamase_39_70,TEM-1,beta-lactamase_39,P62593,1.00533,NO,70,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.169,-2.96,1.791,,,H,A,0.58,-1.34,1.14,,63.99,PHB,-0.980667,0.0495842,0.00193499,1.00533 beta-lactamase_39_I125V,beta-lactamase_39_125,TEM-1,beta-lactamase_39,P62593,1.00533,NO,125,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.441,-2.101,0.66,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.0495842,0.00383964,1.00533 beta-lactamase_156_A225P,beta-lactamase_156_225,TEM-1,beta-lactamase_156,P62593,1.00534,NO,225,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.845,-3.112,1.267,,1,T,B,0.46,-0.38,11.722,11.722,74.48,OHO,-1.39967,0.111618,0.00465057,1.00534 beta-lactamase_156_L219H,beta-lactamase_156_219,TEM-1,beta-lactamase_156,P62593,1.00534,NO,219,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.313,-4.957,3.644,,,I,A,0.55,-0.51,2.321,,74.48,HHB,-1.21533,0.111618,0.00664345,1.00534 beta-lactamase_2500_A200K,beta-lactamase_2500_200,TEM-1,beta-lactamase_2500,P62593,1.00535,NO,200,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.878,-2.669,0.791,,0.757,H,A,0.46,-0.19,0.436,,77.62,HHP,-2.001,0.361275,0.0060056,1.00535 beta-lactamase_39_L191Y,beta-lactamase_39_191,TEM-1,beta-lactamase_39,P62593,1.00535,NO,191,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.087,-3.913,2.826,,,H,A,0.55,0.09,1.372,,63.29,BHH,-1.445,0.0495842,0.00263549,1.00535 beta-lactamase_39_P105K,beta-lactamase_39_105,TEM-1,beta-lactamase_39,P62593,1.00536,NO,105,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.813,-3.454,2.641,,0.226,T,A,0.52,0.8,1.222,,63.29,POH,-1.01533,0.0495842,0.0011981,1.00536 beta-lactamase_39_I140K,beta-lactamase_39_140,TEM-1,beta-lactamase_39,P62593,1.00537,NO,140,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.733,-3.879,2.146,,0.128,H,A,0.48,0.41,1.16,,73.08,PHO,-1.48733,0.0495842,0.00597777,1.00537 beta-lactamase_39_K30H,beta-lactamase_39_30,TEM-1,beta-lactamase_39,P62593,1.00537,NO,30,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-2.307,-4.558,2.251,,0.142,H,A,2.34,-0.65,6.717,,93.01,HBH,-2.32833,0.0495842,0.00448593,1.00537 beta-lactamase_A266S,beta-lactamase_266,TEM-1,beta-lactamase,P62593,1.00537,NO,266,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.369,-2.686,1.317,5.02057,0.175,S,B,0.52,0.07,1.832,,64.34,PHP,-2.08567,0.221079,0.0140785,1.00537 beta-lactamase_0_R92D,beta-lactamase_0_92,TEM-1,beta-lactamase_0,P62593,1.00538,NO,92,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.718,-3.708,1.99,,0.479,E,B,1.2,1.36,2.331,,65.38,BBH,-1.50367,0.0500837,0.00429626,1.00538 beta-lactamase_625_H94L,beta-lactamase_625_94,TEM-1,beta-lactamase_625,P62593,1.00538,NO,94,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-2.5,-3.441,0.941,,0.776,,B,0.17,1.24,19.42,19.42,77.62,HBH,-1.872,0.213352,0.00389226,1.00538 beta-lactamase_625_L284I,beta-lactamase_625_284,TEM-1,beta-lactamase_625,P62593,1.00538,NO,284,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.213352,0.0686156,1.00538 beta-lactamase_156_K109E,beta-lactamase_156_109,TEM-1,beta-lactamase_156,P62593,1.00539,NO,109,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.734,-2.478,0.744,,0.787,G,A,2.34,2.21,6.031,,72.73,ABB,-1.63333,0.111618,0.00462493,1.00539 beta-lactamase_39_H156W,beta-lactamase_39_156,TEM-1,beta-lactamase_39,P62593,1.00539,NO,156,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-3.156,-5.55,2.394,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.0495842,0.00468596,1.00539 beta-lactamase_156_M180L,beta-lactamase_156_180,TEM-1,beta-lactamase_156,P62593,1.0054,NO,180,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-2.795,-3.19,0.395,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.111618,0.00552048,1.0054 beta-lactamase_2500_E61H,beta-lactamase_2500_61,TEM-1,beta-lactamase_2500,P62593,1.0054,NO,61,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.115,-4.518,2.403,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.361275,0.00440955,1.0054 beta-lactamase_39_L218M,beta-lactamase_39_218,TEM-1,beta-lactamase_39,P62593,1.0054,NO,218,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.391,-4.267,2.876,,,I,b,0.55,-0.53,2.038,,74.48,OHH,-1.58867,0.0495842,0.00618274,1.0054 beta-lactamase_156_A123I,beta-lactamase_156_123,TEM-1,beta-lactamase_156,P62593,1.00541,NO,123,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.834,-3.433,2.599,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.111618,0.0010157,1.00541 beta-lactamase_2500_T112S,beta-lactamase_2500_112,TEM-1,beta-lactamase_2500,P62593,1.00541,NO,112,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.186,-2.762,0.576,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.361275,0.00531334,1.00541 beta-lactamase_625_S256E,beta-lactamase_625_256,TEM-1,beta-lactamase_625,P62593,1.00541,NO,256,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.213352,0.00710634,1.00541 beta-lactamase_A280R,beta-lactamase_280,TEM-1,beta-lactamase,P62593,1.00541,NO,280,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.708,-2.082,0.374,4.74932,0.379,H,A,0.52,-0.72,1.785,,68.18,OHP,-1.66433,0.221079,0.0530888,1.00541 beta-lactamase_E102A,beta-lactamase_102,TEM-1,beta-lactamase,P62593,1.00541,NO,102,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.118,-2.327,0.209,6.36157,0.722,S,B,1.5,1.82,1.336,,73.08,HAH,-1.581,0.221079,0.00486633,1.00541 beta-lactamase_156_A200Q,beta-lactamase_156_200,TEM-1,beta-lactamase_156,P62593,1.00542,NO,200,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.878,-3.113,1.235,,0.757,H,A,0.46,-0.19,16.368,16.368,77.62,HHP,-2.001,0.111618,0.0060056,1.00542 beta-lactamase_156_E119S,beta-lactamase_156_119,TEM-1,beta-lactamase_156,P62593,1.00542,NO,119,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.412,-2.681,1.269,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.111618,0.00386966,1.00542 beta-lactamase_2500_D252A,beta-lactamase_2500_252,TEM-1,beta-lactamase_2500,P62593,1.00542,NO,252,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.94,,,,0.766,,B,1.59,1.16,,,67.83,OAO,-2.0965,0.361275,0.00575769,1.00542 beta-lactamase_L223C,beta-lactamase_223,TEM-1,beta-lactamase,P62593,1.00543,NO,223,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.055,-4.721,3.666,5.42318,0.27,,B,1.3,0.09,1.511,,74.48,HHO,-1.35033,0.221079,0.00372793,1.00543 beta-lactamase_625_R41I,beta-lactamase_625_41,TEM-1,beta-lactamase_625,P62593,1.00544,NO,41,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-0.942,-4.008,3.066,,0.321,E,B,1.2,-0.07,1.186,,65.03,HBH,-1.30267,0.213352,0.00123327,1.00544 beta-lactamase_625_A282H,beta-lactamase_625_282,TEM-1,beta-lactamase_625,P62593,1.00545,NO,282,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.213352,0.0449821,1.00545 beta-lactamase_625_Q37R,beta-lactamase_625_37,TEM-1,beta-lactamase_625,P62593,1.00545,NO,37,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.134,-2.096,-0.038,,0.613,H,A,0.64,1.98,1.318,,73.08,APH,-2.06967,0.213352,0.00425833,1.00545 beta-lactamase_156_G90C,beta-lactamase_156_90,TEM-1,beta-lactamase_156,P62593,1.00546,NO,90,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-2.091,-5.167,3.076,,0.598,T,A,0.29,0.32,0.319,,77.62,HOB,-1.52633,0.111618,0.00490273,1.00546 beta-lactamase_2500_Q267D,beta-lactamase_2500_267,TEM-1,beta-lactamase_2500,P62593,1.00546,NO,267,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.361275,0.0102128,1.00546 beta-lactamase_625_L167V,beta-lactamase_625_167,TEM-1,beta-lactamase_625,P62593,1.00546,NO,167,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.138,-2.277,1.139,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.213352,0.00303566,1.00546 beta-lactamase_F14I,beta-lactamase_14,TEM-1,beta-lactamase,P62593,1.00546,NO,14,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-2.736,-2.09,-0.646,,,,,,,1.537,,93.01,HHH,-2.26133,0.221079,0.00277095,1.00546 kka2_1:4_C77S,kka2_1:4_77,Kka2,kka2_1:4,P00552,1.00546,NO,77,C,S,CS,Special,Polar,5.07,5.68,0.61,112,121,105,-16,108.5,89,-19.5,-1.477,-2.746,1.269,,0.229,B,b,0.46,-0.57,2.499,,63.26,OOH,-1.55667,0.168804,0.00441216,1.00546 beta-lactamase_39_E46K,beta-lactamase_39_46,TEM-1,beta-lactamase_39,P62593,1.00547,NO,46,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.94,-3.66,1.72,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.0495842,0.00427568,1.00547 beta-lactamase_39_K109H,beta-lactamase_39_109,TEM-1,beta-lactamase_39,P62593,1.00547,NO,109,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.734,-3.369,1.635,,0.787,G,A,2.34,2.21,7.243,,72.73,ABB,-1.63333,0.0495842,0.00462493,1.00547 beta-lactamase_625_A278L,beta-lactamase_625_278,TEM-1,beta-lactamase_625,P62593,1.00547,NO,278,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.213352,0.0310297,1.00547 beta-lactamase_625_L28F,beta-lactamase_625_28,TEM-1,beta-lactamase_625,P62593,1.00547,NO,28,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.579,-3.916,2.337,,0.277,H,A,0.55,-0.16,2.716,,93.01,PHH,-2.11333,0.213352,0.00359321,1.00547 beta-lactamase_2500_K254V,beta-lactamase_2500_254,TEM-1,beta-lactamase_2500,P62593,1.00548,NO,254,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.361275,0.00369,1.00548 beta-lactamase_625_Q86R,beta-lactamase_625_86,TEM-1,beta-lactamase_625,P62593,1.00548,NO,86,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.4,-2.686,0.286,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.213352,0.00450027,1.00548 beta-lactamase_625_T147M,beta-lactamase_625_147,TEM-1,beta-lactamase_625,P62593,1.00548,NO,147,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.149,-4.573,3.424,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.213352,0.00226017,1.00548 beta-lactamase_39_S256P,beta-lactamase_39_256,TEM-1,beta-lactamase_39,P62593,1.00549,NO,256,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.0495842,0.00710634,1.00549 beta-lactamase_A84Q,beta-lactamase_84,TEM-1,beta-lactamase,P62593,1.00549,NO,84,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.651,-2.658,1.007,5.28927,0.65,T,A,0.52,0.96,1.863,,68.18,AHO,-1.24267,0.221079,0.00503822,1.00549 beta-lactamase_L47L,beta-lactamase_47,TEM-1,beta-lactamase,P62593,1.00549,NO,47,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.876,-1.876,,5.27297,0.007,E,B,1.07,0.2,1.244,,67.83,AHA,-1.639,0.221079,0.00439844,1.00549 beta-lactamase_T112V,beta-lactamase_112,TEM-1,beta-lactamase,P62593,1.00549,NO,112,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.186,-2.929,0.743,6.47162,0.921,T,A,0.77,1.06,2.04,,73.78,HPA,-1.925,0.221079,0.00531334,1.00549 beta-lactamase_39_P250Q,beta-lactamase_39_250,TEM-1,beta-lactamase_39,P62593,1.0055,NO,250,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.0495842,0.00550899,1.0055 beta-lactamase_625_S57F,beta-lactamase_625_57,TEM-1,beta-lactamase_625,P62593,1.0055,NO,57,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.918,-4.274,2.356,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.213352,0.00492804,1.0055 beta-lactamase_625_P60H,beta-lactamase_625_60,TEM-1,beta-lactamase_625,P62593,1.00551,NO,60,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-2.469,-3.266,0.797,,0.256,T,A,0.52,-0.56,3.653,,77.62,BOA,-1.97633,0.213352,0.00521318,1.00551 Pab1_F146M,Pab1_146,Pab1,Pab1,P04147,1.00552,NO,146,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.149,-4.072,2.923,,0.006,H,A,,0.75,,,,PHP,-1.161,0.175299,0.000329265,1.00552 beta-lactamase_156_T198A,beta-lactamase_156_198,TEM-1,beta-lactamase_156,P62593,1.00553,NO,198,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.168,-2.502,0.334,,0.489,,B,0.22,-0.13,10.771,10.771,73.78,HPH,-1.98767,0.111618,0.004311,1.00553 beta-lactamase_625_M66F,beta-lactamase_625_66,TEM-1,beta-lactamase_625,P62593,1.00553,NO,66,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.362,-3.731,2.369,,0.013,,A,0.55,-0.7,1.659,,73.08,OHH,-1.49567,0.213352,0.00412876,1.00553 beta-lactamase_625_R202K,beta-lactamase_625_202,TEM-1,beta-lactamase_625,P62593,1.00553,NO,202,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.292,-3.005,1.713,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.213352,0.00321899,1.00553 beta-lactamase_625_Y95F,beta-lactamase_625_95,TEM-1,beta-lactamase_625,P62593,1.00553,NO,95,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-1.715,-2.096,0.381,,0.122,,b,0.21,-0.37,3.355,,77.62,BHP,-2.16167,0.213352,0.00479449,1.00553 beta-lactamase_N173K,beta-lactamase_173,TEM-1,beta-lactamase,P62593,1.00553,NO,173,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-2.663,-2.711,0.048,7.02497,1.044,T,l,0.09,1.25,1.88,,77.62,OPA,-1.46633,0.221079,0.0033769,1.00553 beta-lactamase_156_L150Q,beta-lactamase_156_150,TEM-1,beta-lactamase_156,P62593,1.00554,NO,150,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.326,-4.106,2.78,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.111618,0.00463171,1.00554 beta-lactamase_2500_A268T,beta-lactamase_2500_268,TEM-1,beta-lactamase_2500,P62593,1.00555,NO,268,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.361275,0.0102525,1.00555 beta-lactamase_625_H151A,beta-lactamase_625_151,TEM-1,beta-lactamase_625,P62593,1.00555,NO,151,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-2.96,-3.11,0.15,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.213352,0.00216946,1.00555 beta-lactamase_156_V157G,beta-lactamase_156_157,TEM-1,beta-lactamase_156,P62593,1.00556,NO,157,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.751,-3.625,1.874,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.111618,0.00506849,1.00556 beta-lactamase_39_E145S,beta-lactamase_39_145,TEM-1,beta-lactamase_39,P62593,1.00556,NO,145,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.357,-2.669,0.312,,0.545,H,A,1.04,0.79,1.199,,77.62,BAH,-2.069,0.0495842,0.00553285,1.00556 beta-lactamase_625_L73G,beta-lactamase_625_73,TEM-1,beta-lactamase_625,P62593,1.00556,NO,73,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.507,-3.739,2.232,,,H,A,0.55,-0.64,2.933,,67.83,HHH,-1.487,0.213352,0.00488983,1.00556 Pab1_K164M,Pab1_164,Pab1,Pab1,P04147,1.00556,NO,164,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-2.298,-4.47,2.172,,,,,,,,,,OBP,-1.41767,0.175299,0.00255241,1.00556 beta-lactamase_156_L219Q,beta-lactamase_156_219,TEM-1,beta-lactamase_156,P62593,1.00557,NO,219,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.313,-4.292,2.979,,,I,A,0.55,-0.51,2.321,,74.48,HHB,-1.21533,0.111618,0.00664345,1.00557 beta-lactamase_156_S122T,beta-lactamase_156_122,TEM-1,beta-lactamase_156,P62593,1.00557,NO,122,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.406,-2.952,0.546,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.111618,0.00497825,1.00557 beta-lactamase_A225S,beta-lactamase_225,TEM-1,beta-lactamase,P62593,1.00557,NO,225,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.845,-2.863,1.018,6.5181,1,T,B,0.58,-0.38,4.077,,74.48,OHO,-1.39967,0.221079,0.00465057,1.00557 PSD95pdz3_A378W,PSD95pdz3_378,PSD95pdz3,PSD95pdz3,P31016,1.00557,NO,378,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.307,-5.004,3.697,4.86582,,,,,14.576,,,,HHH,-1.509,0.0758425,0.000313169,1.00557 beta-lactamase_156_V106K,beta-lactamase_156_106,TEM-1,beta-lactamase_156,P62593,1.00558,NO,106,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.218,-3.831,2.613,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.111618,0.00304168,1.00558 hsp90_Q582M,hsp90_582,hsp90,hsp90,P02829,1.00558,NO,582,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-3.278,-3.858,0,4.91603,0.453,S,B,,0.67,,,,OPH,-3.249,0.368192,0.000222939,1.00558 beta-lactamase_0_S51W,beta-lactamase_0_51,TEM-1,beta-lactamase_0,P62593,1.00559,NO,51,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.526,-5.435,3.909,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.0500837,0.00504821,1.00559 beta-lactamase_156_A182N,beta-lactamase_156_182,TEM-1,beta-lactamase_156,P62593,1.0056,NO,182,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.777,-3.015,1.238,,0.136,H,A,0.46,-0.66,16.784,16.784,93.01,OHH,-1.27367,0.111618,0.00559099,1.0056 beta-lactamase_39_I171K,beta-lactamase_39_171,TEM-1,beta-lactamase_39,P62593,1.0056,NO,171,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-2.431,-2.528,0.097,,0.361,,B,0.48,0.53,16.954,16.954,77.62,HHO,-1.55533,0.0495842,0.00623355,1.0056 beta-lactamase_625_N274S,beta-lactamase_625_274,TEM-1,beta-lactamase_625,P62593,1.0056,NO,274,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.213352,0.0110418,1.0056 beta-lactamase_L167I,beta-lactamase_167,TEM-1,beta-lactamase,P62593,1.0056,NO,167,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.138,-3.085,1.947,5.13111,0.015,G,A,0.08,-0.63,0.4,,64.69,AHP,-1.30767,0.221079,0.00303566,1.0056 beta-lactamase_T112N,beta-lactamase_112,TEM-1,beta-lactamase,P62593,1.0056,NO,112,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.186,-2.739,0.553,6.47162,0.921,T,A,0.77,1.06,2.04,,73.78,HPA,-1.925,0.221079,0.00531334,1.0056 beta-lactamase_39_L135A,beta-lactamase_39_135,TEM-1,beta-lactamase_39,P62593,1.00561,NO,135,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.002,-3.131,2.129,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.0495842,0.00244423,1.00561 beta-lactamase_625_E145R,beta-lactamase_625_145,TEM-1,beta-lactamase_625,P62593,1.00561,NO,145,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.357,-2.676,0.319,,0.545,H,A,1.04,0.79,2.64,,77.62,BAH,-2.069,0.213352,0.00553285,1.00561 beta-lactamase_156_T107A,beta-lactamase_156_107,TEM-1,beta-lactamase_156,P62593,1.00562,NO,107,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.117,-2.274,1.157,,,G,A,0.22,-0.06,0.341,,67.83,HPA,-1.265,0.111618,0.00239347,1.00562 beta-lactamase_625_G226C,beta-lactamase_625_226,TEM-1,beta-lactamase_625,P62593,1.00562,NO,226,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.461,-3.342,1.881,,0.701,T,l,0.29,-0.25,3.199,,74.48,HOH,-1.42933,0.213352,0.00665294,1.00562 Pab1_L133I,Pab1_133,Pab1,Pab1,P04147,1.00562,NO,133,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.039,-2.702,1.663,,0.015,,B,1.75,1.03,,,,PHB,-1.22,0.175299,0.000345939,1.00562 PSD95pdz3_K355L,PSD95pdz3_355,PSD95pdz3,PSD95pdz3,P31016,1.00563,NO,355,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.416,-3.04,1.624,5.56865,,,,,17.2556,,,,BBO,-1.33533,0.0758425,0.00063703,1.00563 beta-lactamase_39_L137F,beta-lactamase_39_137,TEM-1,beta-lactamase_39,P62593,1.00564,NO,137,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.03,-3.682,2.652,,,H,A,0.55,-0.38,0.674,,42.31,HHP,-1.58933,0.0495842,0.00278599,1.00564 beta-lactamase_625_G194R,beta-lactamase_625_194,TEM-1,beta-lactamase_625,P62593,1.00564,NO,194,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.396,-3.912,2.516,,0.276,S,b,0.29,0.36,3.593,,67.83,POA,-1.832,0.213352,0.00392163,1.00564 kka2_1:8_F37V,kka2_1:8_37,Kka2,kka2_1:8,P00552,1.00564,NO,37,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.427,-2.858,1.431,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.100394,0.00586193,1.00564 kka2_1:8_F37V,kka2_1:8_37,Kka2,kka2_1:8,P00552,1.00564,NO,37,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.427,-2.858,1.431,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.100394,0.00586193,1.00564 beta-lactamase_39_T178R,beta-lactamase_39_178,TEM-1,beta-lactamase_39,P62593,1.00565,NO,178,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-0.791,-3.708,2.917,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.0495842,0.000684366,1.00565 beta-lactamase_39_V29W,beta-lactamase_39_29,TEM-1,beta-lactamase_39,P62593,1.00565,NO,29,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-2.856,-5.465,2.609,,0.733,H,A,0.44,-0.78,1.287,,93.01,HHB,-2.24733,0.0495842,0.00318969,1.00565 beta-lactamase_G236G,beta-lactamase_236,TEM-1,beta-lactamase,P62593,1.00565,NO,236,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.784,-0.784,,4.7915,0.241,,b,0.23,-0.59,1.883,,64.69,HOA,-1.36933,0.221079,0.00162372,1.00565 beta-lactamase_156_R275L,beta-lactamase_156_275,TEM-1,beta-lactamase_156,P62593,1.00566,NO,275,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.111618,0.0141984,1.00566 beta-lactamase_D250A,beta-lactamase_250,TEM-1,beta-lactamase,P62593,1.00566,NO,250,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.335,-2.561,0.226,5.72026,0.89,T,L,0.23,1.53,24.737,24.737,66.08,OAO,-1.85133,0.221079,0.00550899,1.00566 beta-lactamase_Q97T,beta-lactamase_97,TEM-1,beta-lactamase,P62593,1.00566,NO,97,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.072,-2.713,0.641,6.30204,0.823,G,A,1.1,2.42,1.157,,77.62,PPP,-2.43833,0.221079,0.0045116,1.00566 beta-lactamase_156_L191T,beta-lactamase_156_191,TEM-1,beta-lactamase_156,P62593,1.00567,NO,191,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.087,-3.447,2.36,,,H,A,0.55,0.09,1.372,,63.29,BHH,-1.445,0.111618,0.00263549,1.00567 beta-lactamase_39_D155N,beta-lactamase_39_155,TEM-1,beta-lactamase_39,P62593,1.00568,NO,155,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.889,-2.502,1.613,,0.049,,B,0.75,-0.9,3.208,,64.69,OAB,-1.62267,0.0495842,0.00135315,1.00568 beta-lactamase_625_G194N,beta-lactamase_625_194,TEM-1,beta-lactamase_625,P62593,1.00568,NO,194,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.396,-2.573,1.177,,0.276,S,b,0.29,0.36,3.593,,67.83,POA,-1.832,0.213352,0.00392163,1.00568 beta-lactamase_625_K53I,beta-lactamase_625_53,TEM-1,beta-lactamase_625,P62593,1.00568,NO,53,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-2.313,-4.015,1.702,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.213352,0.00383383,1.00568 beta-lactamase_156_C75L,beta-lactamase_156_75,TEM-1,beta-lactamase_156,P62593,1.00569,NO,75,C,L,CL,Special,Hydrophobic,5.07,9.7088,4.6388,198,121,131,10,108.5,166.7,58.2,-1.245,-3.28,2.035,,,H,A,0.46,-0.87,0.876,,50,HOO,-1.24333,0.111618,0.0034616,1.00569 beta-lactamase_2500_P60E,beta-lactamase_2500_60,TEM-1,beta-lactamase_2500,P62593,1.00569,NO,60,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-2.469,-2.856,0.387,,0.256,T,A,0.52,-0.56,1.581,,77.62,BOA,-1.97633,0.361275,0.00521318,1.00569 beta-lactamase_625_A230I,beta-lactamase_625_230,TEM-1,beta-lactamase_625,P62593,1.00569,NO,230,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.154,-3.843,2.689,,0.01,E,B,0.46,-1.17,0.777,,50,HHA,-1.079,0.213352,0.00516841,1.00569 gb1_L233C,gb1_233,gb1,gb1,P06654,1.00569,NO,233,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-2.678,-4.649,1.971,,,,,,,0.822,,45.54,HHP,-2.30267,0.177985,0.00266958,1.00569 beta-lactamase_156_G194F,beta-lactamase_156_194,TEM-1,beta-lactamase_156,P62593,1.00571,NO,194,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.396,-4.382,2.986,,0.276,S,b,0.29,0.36,1.346,,67.83,POA,-1.832,0.111618,0.00392163,1.00571 beta-lactamase_39_Q276W,beta-lactamase_39_276,TEM-1,beta-lactamase_39,P62593,1.00571,NO,276,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.0495842,0.0191712,1.00571 beta-lactamase_625_E166A,beta-lactamase_625_166,TEM-1,beta-lactamase_625,P62593,1.00571,NO,166,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.756,-2.056,0.3,,0.508,G,A,1.04,1.05,2.124,,73.08,OAH,-1.42233,0.213352,0.00512989,1.00571 beta-lactamase_625_E56S,beta-lactamase_625_56,TEM-1,beta-lactamase_625,P62593,1.00571,NO,56,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.043,-2.169,0.126,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.213352,0.00238534,1.00571 beta-lactamase_156_V260T,beta-lactamase_156_260,TEM-1,beta-lactamase_156,P62593,1.00572,NO,260,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.111618,0.00471757,1.00572 beta-lactamase_39_L150T,beta-lactamase_39_150,TEM-1,beta-lactamase_39,P62593,1.00572,NO,150,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.326,-2.5,1.174,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.0495842,0.00463171,1.00572 beta-lactamase_39_T107A,beta-lactamase_39_107,TEM-1,beta-lactamase_39,P62593,1.00572,NO,107,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.117,-2.274,1.157,,,G,A,0.22,-0.06,2.686,,67.83,HPA,-1.265,0.0495842,0.00239347,1.00572 beta-lactamase_2500_K254T,beta-lactamase_2500_254,TEM-1,beta-lactamase_2500,P62593,1.00573,NO,254,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.361275,0.00369,1.00573 beta-lactamase_39_L196N,beta-lactamase_39_196,TEM-1,beta-lactamase_39,P62593,1.00573,NO,196,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-2.478,-3.953,1.475,,0.518,S,A,0.55,1.35,12.152,12.152,77.62,AHH,-1.839,0.0495842,0.00512144,1.00573 beta-lactamase_156_S122A,beta-lactamase_156_122,TEM-1,beta-lactamase_156,P62593,1.00574,NO,122,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.406,-2.18,-0.226,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.111618,0.00497825,1.00574 beta-lactamase_2500_A148R,beta-lactamase_2500_148,TEM-1,beta-lactamase_2500,P62593,1.00574,NO,148,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.757,-2.456,0.699,,0.379,H,A,0.46,-0.55,2.117,,72.73,PHH,-1.40167,0.361275,0.00547053,1.00574 beta-lactamase_2500_T112R,beta-lactamase_2500_112,TEM-1,beta-lactamase_2500,P62593,1.00574,NO,112,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.186,-3.88,1.694,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.361275,0.00531334,1.00574 beta-lactamase_156_R41C,beta-lactamase_156_41,TEM-1,beta-lactamase_156,P62593,1.00575,NO,41,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-0.942,-5.05,4.108,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.111618,0.00123327,1.00575 beta-lactamase_39_T138D,beta-lactamase_39_138,TEM-1,beta-lactamase_39,P62593,1.00575,NO,138,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.506,-2.325,-0.181,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.0495842,0.00487868,1.00575 beta-lactamase_625_N50V,beta-lactamase_625_50,TEM-1,beta-lactamase_625,P62593,1.00576,NO,50,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-2.979,-2.913,-0.066,,0.912,T,A,0.61,1.24,3.446,,77.62,HPP,-2.134,0.213352,0.0047211,1.00576 beta-lactamase_156_T193F,beta-lactamase_156_193,TEM-1,beta-lactamase_156,P62593,1.00577,NO,193,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.914,-2.368,0.454,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.111618,0.00482669,1.00577 beta-lactamase_39_V72P,beta-lactamase_39_72,TEM-1,beta-lactamase_39,P62593,1.00577,NO,72,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.658,-2.442,0.784,,,H,A,0.44,-1.03,1.92,,65.73,BHH,-1.32167,0.0495842,0.00501194,1.00577 beta-lactamase_625_A40G,beta-lactamase_625_40,TEM-1,beta-lactamase_625,P62593,1.00577,NO,40,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.402,-1.32,-0.082,,0.155,S,B,0.46,0.21,1.357,,73.78,OHB,-1.40267,0.213352,0.00490026,1.00577 Pab1_E175K,Pab1_175,Pab1,Pab1,P04147,1.00577,NO,175,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.055,-3.327,1.272,,,,,,,,,,AAA,-1.82667,0.175299,0.00203137,1.00577 beta-lactamase_0_A148C,beta-lactamase_0_148,TEM-1,beta-lactamase_0,P62593,1.00578,NO,148,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.757,-5.042,3.285,,0.379,H,A,0.46,-0.55,19.42,19.42,72.73,PHH,-1.40167,0.0500837,0.00547053,1.00578 beta-lactamase_156_K32I,beta-lactamase_156_32,TEM-1,beta-lactamase_156,P62593,1.00578,NO,32,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.984,-2.835,0.851,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.111618,0.00401283,1.00578 beta-lactamase_156_M270F,beta-lactamase_156_270,TEM-1,beta-lactamase_156,P62593,1.00578,NO,270,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.111618,0.00767762,1.00578 beta-lactamase_156_S57W,beta-lactamase_156_57,TEM-1,beta-lactamase_156,P62593,1.00578,NO,57,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.918,-5.449,3.531,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.111618,0.00492804,1.00578 beta-lactamase_39_R63S,beta-lactamase_39_63,TEM-1,beta-lactamase_39,P62593,1.00578,NO,63,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-0.943,-3.435,2.492,,0.218,,B,1.2,-0.31,0.326,,44.06,ABH,-0.992333,0.0495842,0.00126938,1.00578 beta-lactamase_156_E166L,beta-lactamase_156_166,TEM-1,beta-lactamase_156,P62593,1.00579,NO,166,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.756,-2.872,1.116,,0.508,G,A,1.04,1.05,2.393,,73.08,OAH,-1.42233,0.111618,0.00512989,1.00579 beta-lactamase_625_A84E,beta-lactamase_625_84,TEM-1,beta-lactamase_625,P62593,1.00579,NO,84,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.651,-2.632,0.981,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.213352,0.00503822,1.00579 beta-lactamase_625_D113Y,beta-lactamase_625_113,TEM-1,beta-lactamase_625,P62593,1.00579,NO,113,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.829,-4.441,2.612,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.213352,0.00474112,1.00579 beta-lactamase_625_S80F,beta-lactamase_625_80,TEM-1,beta-lactamase_625,P62593,1.00579,NO,80,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.029,-4.287,2.258,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.213352,0.00565569,1.00579 beta-lactamase_625_T139E,beta-lactamase_625_139,TEM-1,beta-lactamase_625,P62593,1.00579,NO,139,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.901,-2.44,0.539,,0.216,H,A,0.22,0.39,2.256,,77.62,PPH,-2.04667,0.213352,0.00441837,1.00579 PSD95pdz3_Q358I,PSD95pdz3_358,PSD95pdz3,PSD95pdz3,P31016,1.00579,NO,358,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-1.699,-3.692,1.993,5.21282,,,,,14.8844,,,,APH,-1.531,0.0758425,0.000594893,1.00579 beta-lactamase_156_V157I,beta-lactamase_156_157,TEM-1,beta-lactamase_156,P62593,1.0058,NO,157,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.751,-2.621,0.87,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.111618,0.00506849,1.0058 beta-lactamase_156_V259C,beta-lactamase_156_259,TEM-1,beta-lactamase_156,P62593,1.0058,NO,259,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.111618,0.0070773,1.0058 beta-lactamase_156_V29N,beta-lactamase_156_29,TEM-1,beta-lactamase_156,P62593,1.0058,NO,29,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-2.856,-2.832,-0.024,,0.733,H,A,0.44,-0.78,3.685,,93.01,HHB,-2.24733,0.111618,0.00318969,1.0058 beta-lactamase_625_E61T,beta-lactamase_625_61,TEM-1,beta-lactamase_625,P62593,1.0058,NO,61,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.115,-3.52,1.405,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.213352,0.00440955,1.0058 beta-lactamase_625_T186S,beta-lactamase_625_186,TEM-1,beta-lactamase_625,P62593,1.0058,NO,186,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.522,-2.471,-0.051,,0.396,H,A,0.22,-0.28,0.515,,77.62,HPP,-1.77633,0.213352,0.00485034,1.0058 beta-lactamase_156_R176E,beta-lactamase_156_176,TEM-1,beta-lactamase_156,P62593,1.00581,NO,176,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-0.863,-3.215,2.352,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.111618,0.00105554,1.00581 beta-lactamase_2500_I171A,beta-lactamase_2500_171,TEM-1,beta-lactamase_2500,P62593,1.00581,NO,171,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-2.431,-2.242,-0.189,,0.361,,B,0.48,0.53,1.66,,77.62,HHO,-1.55533,0.361275,0.00623355,1.00581 beta-lactamase_625_V117L,beta-lactamase_625_117,TEM-1,beta-lactamase_625,P62593,1.00581,NO,117,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.53,-1.606,0.076,,,H,A,0.44,-0.34,1.23,,65.03,PHB,-1.741,0.213352,0.00467906,1.00581 beta-lactamase_156_R118K,beta-lactamase_156_118,TEM-1,beta-lactamase_156,P62593,1.00582,NO,118,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.413,-3.492,1.079,,0.457,H,A,1.2,1.39,2.231,,77.62,HBA,-1.785,0.111618,0.00538794,1.00582 beta-lactamase_625_E210T,beta-lactamase_625_210,TEM-1,beta-lactamase_625,P62593,1.00582,NO,210,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.319,-2.842,0.523,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.213352,0.00663582,1.00582 kka2_1:8_V198T,kka2_1:8_198,Kka2,kka2_1:8,P00552,1.00582,NO,198,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.719,-2.237,0.518,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.100394,0.00835002,1.00582 kka2_1:8_V198T,kka2_1:8_198,Kka2,kka2_1:8,P00552,1.00582,NO,198,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.719,-2.237,0.518,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.100394,0.00835002,1.00582 beta-lactamase_156_E166K,beta-lactamase_156_166,TEM-1,beta-lactamase_156,P62593,1.00583,NO,166,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.756,-2.625,0.869,,0.508,G,A,1.04,1.05,2.393,,73.08,OAH,-1.42233,0.111618,0.00512989,1.00583 beta-lactamase_39_P105G,beta-lactamase_39_105,TEM-1,beta-lactamase_39,P62593,1.00583,NO,105,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.813,-3.321,2.508,,0.226,T,A,0.52,0.8,1.222,,63.29,POH,-1.01533,0.0495842,0.0011981,1.00583 beta-lactamase_39_K286S,beta-lactamase_39_286,TEM-1,beta-lactamase_39,P62593,1.00585,NO,286,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.0495842,,1.00585 beta-lactamase_625_K32Y,beta-lactamase_625_32,TEM-1,beta-lactamase_625,P62593,1.00585,NO,32,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.984,-4.317,2.333,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.213352,0.00401283,1.00585 beta-lactamase_625_H24F,beta-lactamase_625_24,TEM-1,beta-lactamase_625,P62593,1.00586,NO,24,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-2.481,-4.152,1.671,,,,,,,2.708,,93.01,OBO,-2.0035,0.213352,0.00238894,1.00586 Pab1_F146L,Pab1_146,Pab1,Pab1,P04147,1.00587,NO,146,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.149,-2.725,1.576,,0.006,H,A,,0.75,,,,PHP,-1.161,0.175299,0.000329265,1.00587 beta-lactamase_625_G194Y,beta-lactamase_625_194,TEM-1,beta-lactamase_625,P62593,1.00588,NO,194,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.396,-4.427,3.031,,0.276,S,b,0.29,0.36,3.593,,67.83,POA,-1.832,0.213352,0.00392163,1.00588 beta-lactamase_156_A132S,beta-lactamase_156_132,TEM-1,beta-lactamase_156,P62593,1.00589,NO,132,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.9,-2.411,1.511,,,H,A,0.46,-0.93,10.621,,64.69,PHH,-1.138,0.111618,0.000962524,1.00589 Pab1_N187S,Pab1_187,Pab1,Pab1,P04147,1.00589,NO,187,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-1.224,-2.856,1.632,,0.456,S,b,,1.87,,,,HPO,-1.272,0.175299,0.00083165,1.00589 beta-lactamase_156_R189A,beta-lactamase_156_189,TEM-1,beta-lactamase_156,P62593,1.0059,NO,189,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.844,-2.739,0.895,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.111618,0.0050699,1.0059 beta-lactamase_625_A77S,beta-lactamase_625_77,TEM-1,beta-lactamase_625,P62593,1.0059,NO,77,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.234,-2.62,1.386,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.213352,0.00282362,1.0059 beta-lactamase_625_K53M,beta-lactamase_625_53,TEM-1,beta-lactamase_625,P62593,1.0059,NO,53,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-2.313,-4.641,2.328,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.213352,0.00383383,1.0059 beta-lactamase_625_L38N,beta-lactamase_625_38,TEM-1,beta-lactamase_625,P62593,1.0059,NO,38,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.343,-4.007,2.664,,0.088,H,A,0.55,0.2,1.986,,64.34,PHO,-1.78033,0.213352,0.00373244,1.0059 beta-lactamase_2500_A148I,beta-lactamase_2500_148,TEM-1,beta-lactamase_2500,P62593,1.00591,NO,148,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.757,-4.049,2.292,,0.379,H,A,0.46,-0.55,2.117,,72.73,PHH,-1.40167,0.361275,0.00547053,1.00591 beta-lactamase_2500_S283E,beta-lactamase_2500_283,TEM-1,beta-lactamase_2500,P62593,1.00592,NO,283,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.361275,0.0429138,1.00592 beta-lactamase_2500_K254H,beta-lactamase_2500_254,TEM-1,beta-lactamase_2500,P62593,1.00593,NO,254,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.361275,0.00369,1.00593 beta-lactamase_39_S57W,beta-lactamase_39_57,TEM-1,beta-lactamase_39,P62593,1.00593,NO,57,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.918,-5.449,3.531,,0.352,E,B,0.27,-0.18,2.3,,72.73,APH,-2.29167,0.0495842,0.00492804,1.00593 beta-lactamase_39_S80I,beta-lactamase_39_80,TEM-1,beta-lactamase_39,P62593,1.00593,NO,80,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.029,-3.787,1.758,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.0495842,0.00565569,1.00593 beta-lactamase_625_K53V,beta-lactamase_625_53,TEM-1,beta-lactamase_625,P62593,1.00593,NO,53,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-2.313,-3.678,1.365,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.213352,0.00383383,1.00593 beta-lactamase_2500_A84Q,beta-lactamase_2500_84,TEM-1,beta-lactamase_2500,P62593,1.00594,NO,84,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.651,-2.658,1.007,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.361275,0.00503822,1.00594 beta-lactamase_2500_T263L,beta-lactamase_2500_263,TEM-1,beta-lactamase_2500,P62593,1.00594,NO,263,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.361275,0.0110582,1.00594 beta-lactamase_39_M66G,beta-lactamase_39_66,TEM-1,beta-lactamase_39,P62593,1.00594,NO,66,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.362,-3.751,2.389,,0.013,,A,0.55,-0.7,1.319,,73.08,OHH,-1.49567,0.0495842,0.00412876,1.00594 beta-lactamase_625_M67G,beta-lactamase_625_67,TEM-1,beta-lactamase_625,P62593,1.00594,NO,67,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-2.231,-2.754,0.523,,0.006,G,P,0.55,-0.81,2.653,,65.03,HHP,-1.502,0.213352,0.00409753,1.00594 Pab1_F129Y,Pab1_129,Pab1,Pab1,P04147,1.00594,NO,129,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.269,-2.031,0.762,,0.219,E,B,0.03,-0.07,1.307,,73.83,HHH,-1.27533,0.175299,0.000625182,1.00594 beta-lactamase_156_T116N,beta-lactamase_156_116,TEM-1,beta-lactamase_156,P62593,1.00595,NO,116,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.28,-2.515,1.235,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.111618,0.00336175,1.00595 beta-lactamase_39_G236S,beta-lactamase_39_236,TEM-1,beta-lactamase_39,P62593,1.00595,NO,236,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.784,-2.475,1.691,,0.241,,b,0.29,-0.59,1.883,,64.69,HOO,-1.025,0.0495842,0.00162372,1.00595 beta-lactamase_39_V82L,beta-lactamase_39_82,TEM-1,beta-lactamase_39,P62593,1.00595,NO,82,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.325,-2.426,1.101,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.0495842,0.00397046,1.00595 beta-lactamase_625_G281S,beta-lactamase_625_281,TEM-1,beta-lactamase_625,P62593,1.00595,NO,281,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-2.247,-3.28,1.033,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.213352,0.0406482,1.00595 beta-lactamase_A16H,beta-lactamase_16,TEM-1,beta-lactamase,P62593,1.00595,NO,16,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,,-3.054,1.119,,,,,,,,,,HHH,,0.221079,0.00245392,1.00595 beta-lactamase_A77C,beta-lactamase_77,TEM-1,beta-lactamase,P62593,1.00595,NO,77,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.234,-4.708,3.474,4.75777,0.039,H,A,0.52,-0.56,1.708,,64.34,OHH,-1.294,0.221079,0.00282362,1.00595 beta-lactamase_A77Q,beta-lactamase_77,TEM-1,beta-lactamase,P62593,1.00595,NO,77,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.234,-4.052,2.818,4.75777,0.039,H,A,0.52,-0.56,1.708,,64.34,OHH,-1.294,0.221079,0.00282362,1.00595 beta-lactamase_G39R,beta-lactamase_39,TEM-1,beta-lactamase,P62593,1.00595,NO,39,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.864,-3.077,1.213,5.35574,0.701,T,L,0.23,0.47,29.926,29.926,77.62,HOH,-1.53633,0.221079,0.00487611,1.00595 beta-lactamase_H5K,beta-lactamase_5,TEM-1,beta-lactamase,P62593,1.00595,NO,5,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-2.698,-2.47,-0.228,,,,,,,1.865,,72.73,PBH,-2.36967,0.221079,0.00292712,1.00595 beta-lactamase_I11C,beta-lactamase_11,TEM-1,beta-lactamase,P62593,1.00595,NO,11,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.745,-4.758,3.013,,,,,,,3.135,,66.08,HHO,-1.79467,0.221079,0.00261325,1.00595 beta-lactamase_L282M,beta-lactamase_282,TEM-1,beta-lactamase,P62593,1.00595,NO,282,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.586,-2.363,0.777,5.16743,0.007,H,A,1.07,0.34,31.31,31.31,63.99,PHH,-1.82367,0.221079,0.0449821,1.00595 beta-lactamase_Q97S,beta-lactamase_97,TEM-1,beta-lactamase,P62593,1.00595,NO,97,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.072,-3.388,1.316,6.30204,0.823,G,A,1.1,2.42,1.157,,77.62,PPP,-2.43833,0.221079,0.0045116,1.00595 beta-lactamase_R273G,beta-lactamase_273,TEM-1,beta-lactamase,P62593,1.00595,NO,273,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.314,-2.465,0.151,,0.564,H,A,1.2,1.57,,,73.78,ABP,-1.841,0.221079,0.0077952,1.00595 beta-lactamase_625_L196M,beta-lactamase_625_196,TEM-1,beta-lactamase_625,P62593,1.00596,NO,196,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-2.478,-3.442,0.964,,0.518,S,A,0.55,1.35,12.152,12.152,77.62,AHH,-1.839,0.213352,0.00512144,1.00596 PSD95pdz3_V365N,PSD95pdz3_365,PSD95pdz3,PSD95pdz3,P31016,1.00596,NO,365,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.592,-3.804,2.212,5.03791,,,,,18.9657,2.364,,81.35,OHA,-1.288,0.0758425,0.000649764,1.00596 beta-lactamase_156_D83H,beta-lactamase_156_83,TEM-1,beta-lactamase_156,P62593,1.00597,NO,83,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.066,-4.503,3.437,,0.354,H,A,0.75,0.22,1.281,,48.95,HAH,-1.34733,0.111618,0.00205968,1.00597 beta-lactamase_156_G216M,beta-lactamase_156_216,TEM-1,beta-lactamase_156,P62593,1.00597,NO,216,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.477,-4.925,3.448,,0.437,I,A,0.29,-0.58,12.464,12.464,74.48,HOO,-1.68067,0.111618,0.00639568,1.00597 beta-lactamase_39_Y95G,beta-lactamase_39_95,TEM-1,beta-lactamase_39,P62593,1.00597,NO,95,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-1.715,-3.781,2.066,,0.122,,b,0.21,-0.37,2.341,,77.62,BHP,-2.16167,0.0495842,0.00479449,1.00597 beta-lactamase_625_T69H,beta-lactamase_625_69,TEM-1,beta-lactamase_625,P62593,1.00597,NO,69,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-0.973,-4.716,3.743,,,G,A,0.22,-1.24,2.716,,93.01,PPH,-1.01833,0.213352,0.00127498,1.00597 beta-lactamase_2500_Q37N,beta-lactamase_2500_37,TEM-1,beta-lactamase_2500,P62593,1.00598,NO,37,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.134,-3.706,1.572,,0.613,H,A,0.64,1.98,1.318,,73.08,APH,-2.06967,0.361275,0.00425833,1.00598 beta-lactamase_625_E169C,beta-lactamase_625_169,TEM-1,beta-lactamase_625,P62593,1.00599,NO,169,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.23,-5.088,3.858,,0.337,,A,1.04,1,1.806,,73.08,PAH,-1.16533,0.213352,0.00400994,1.00599 Pab1_K166R,Pab1_166,Pab1,Pab1,P04147,1.00599,NO,166,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.262,-1.881,0.619,,0.299,,l,,0,,,,PBO,-1.21033,0.175299,0.0011038,1.00599 PSD95pdz3_D348Q,PSD95pdz3_348,PSD95pdz3,PSD95pdz3,P31016,1.00599,NO,348,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.264,-3.356,2.092,5.02473,,,,,16.8925,,,,HAH,-1.306,0.0758425,0.000731866,1.00599 beta-lactamase_2500_S283Q,beta-lactamase_2500_283,TEM-1,beta-lactamase_2500,P62593,1.006,NO,283,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.361275,0.0429138,1.006 beta-lactamase_625_E210R,beta-lactamase_625_210,TEM-1,beta-lactamase_625,P62593,1.006,NO,210,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.319,-3.045,0.726,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.213352,0.00663582,1.006 beta-lactamase_625_M127Q,beta-lactamase_625_127,TEM-1,beta-lactamase_625,P62593,1.006,NO,127,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-2.251,-2.96,0.709,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.213352,0.00437927,1.006 beta-lactamase_625_N168T,beta-lactamase_625_168,TEM-1,beta-lactamase_625,P62593,1.006,NO,168,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-1.029,-2.214,1.185,,0.113,G,A,0.61,-0.4,1.014,,44.41,HPA,-1.13233,0.213352,0.00288667,1.006 gb1_A260C,gb1_260,gb1,gb1,P06654,1.006,NO,260,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.486,-4.384,2.898,,,,,,,0.173,,9.6,HHP,-1.70967,0.177985,0.0055808,1.006 hsp90_S586S,hsp90_586,hsp90,hsp90,P02829,1.006,NO,586,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.764,-2.764,,4.65438,,,B,0.93,0.15,,,,HPH,-3.157,0.368192,0.000222939,1.006 Pab1_G177V,Pab1_177,Pab1,Pab1,P04147,1.006,NO,177,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-2.24,-3.446,1.206,,,,,,,,,,AOH,-1.94067,0.175299,0.00170727,1.006 beta-lactamase_156_L89S,beta-lactamase_156_89,TEM-1,beta-lactamase_156,P62593,1.00601,NO,89,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.096,-3.54,2.444,,0.168,T,A,0.55,0.63,2.633,,64.34,PHO,-1.75767,0.111618,0.00207068,1.00601 beta-lactamase_2500_E238K,beta-lactamase_2500_238,TEM-1,beta-lactamase_2500,P62593,1.00602,NO,238,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.361275,0.00743256,1.00602 beta-lactamase_39_E279A,beta-lactamase_39_279,TEM-1,beta-lactamase_39,P62593,1.00602,NO,279,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.0495842,0.0192826,1.00602 beta-lactamase_625_R162N,beta-lactamase_625_162,TEM-1,beta-lactamase_625,P62593,1.00602,NO,162,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.016,-3.588,2.572,,0.124,S,B,1.2,-0.37,1.445,,64.69,ABH,-1.25,0.213352,0.000561334,1.00602 beta-lactamase_625_T269C,beta-lactamase_625_269,TEM-1,beta-lactamase_625,P62593,1.00602,NO,269,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.213352,0.00950944,1.00602 beta-lactamase_156_E166T,beta-lactamase_156_166,TEM-1,beta-lactamase_156,P62593,1.00603,NO,166,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.756,-2.857,1.101,,0.508,G,A,1.04,1.05,2.393,,73.08,OAH,-1.42233,0.111618,0.00512989,1.00603 beta-lactamase_39_S96L,beta-lactamase_39_96,TEM-1,beta-lactamase_39,P62593,1.00603,NO,96,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.27,-3.527,1.257,,0.368,,b,0.27,0.39,2.516,,73.78,HPP,-2.019,0.0495842,0.00551835,1.00603 beta-lactamase_625_G52Q,beta-lactamase_625_52,TEM-1,beta-lactamase_625,P62593,1.00603,NO,52,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.149,-2.995,1.846,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.213352,0.00340138,1.00603 Pab1_P135R,Pab1_135,Pab1,Pab1,P04147,1.00603,NO,135,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.457,-3.682,2.225,,,,,,,6.41,,81.8,BOA,-1.53367,0.175299,0.00148028,1.00603 beta-lactamase_2500_A182R,beta-lactamase_2500_182,TEM-1,beta-lactamase_2500,P62593,1.00604,NO,182,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.777,-2.31,0.533,,0.136,H,A,0.46,-0.66,2.032,,93.01,OHH,-1.27367,0.361275,0.00559099,1.00604 beta-lactamase_625_A77D,beta-lactamase_625_77,TEM-1,beta-lactamase_625,P62593,1.00604,NO,77,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.234,-3.775,2.541,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.213352,0.00282362,1.00604 beta-lactamase_156_G52R,beta-lactamase_156_52,TEM-1,beta-lactamase_156,P62593,1.00605,NO,52,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.149,-3.956,2.807,,0.299,,l,0.29,-0.04,1.179,,64.69,POB,-1.66267,0.111618,0.00340138,1.00605 beta-lactamase_39_I277C,beta-lactamase_39_277,TEM-1,beta-lactamase_39,P62593,1.00605,NO,277,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.0495842,0.0169305,1.00605 beta-lactamase_625_K286S,beta-lactamase_625_286,TEM-1,beta-lactamase_625,P62593,1.00605,NO,286,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.213352,,1.00605 beta-lactamase_625_L284S,beta-lactamase_625_284,TEM-1,beta-lactamase_625,P62593,1.00605,NO,284,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.213352,0.0686156,1.00605 beta-lactamase_2500_L196Q,beta-lactamase_2500_196,TEM-1,beta-lactamase_2500,P62593,1.00606,NO,196,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-2.478,-3.242,0.764,,0.518,S,A,0.55,1.35,7.897,,77.62,AHH,-1.839,0.361275,0.00512144,1.00606 beta-lactamase_39_G114S,beta-lactamase_39_114,TEM-1,beta-lactamase_39,P62593,1.00606,NO,114,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.094,-2.588,1.494,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.0495842,0.00224919,1.00606 beta-lactamase_39_T178K,beta-lactamase_39_178,TEM-1,beta-lactamase_39,P62593,1.00606,NO,178,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-0.791,-3.457,2.666,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.0495842,0.000684366,1.00606 beta-lactamase_625_E195K,beta-lactamase_625_195,TEM-1,beta-lactamase_625,P62593,1.00606,NO,195,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.186,-2.529,0.343,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.213352,0.00496565,1.00606 beta-lactamase_A182A,beta-lactamase_182,TEM-1,beta-lactamase,P62593,1.00606,NO,182,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.777,-1.777,,4.98609,0.136,H,A,0.52,-0.66,2.032,,93.01,OHH,-1.27367,0.221079,0.00559099,1.00606 PSD95pdz3_A390G,PSD95pdz3_390,PSD95pdz3,PSD95pdz3,P31016,1.00606,NO,390,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.307,-2.59,1.283,5.03823,,,,,12.46,,,,HHP,-1.54467,0.0758425,0.00104603,1.00606 beta-lactamase_39_M127I,beta-lactamase_39_127,TEM-1,beta-lactamase_39,P62593,1.00607,NO,127,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-2.251,-2.439,0.188,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.0495842,0.00437927,1.00607 beta-lactamase_625_S57V,beta-lactamase_625_57,TEM-1,beta-lactamase_625,P62593,1.00607,NO,57,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.918,-2.889,0.971,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.213352,0.00492804,1.00607 beta-lactamase_39_V78H,beta-lactamase_39_78,TEM-1,beta-lactamase_39,P62593,1.00609,NO,78,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.459,-5.015,3.556,,,H,A,0.44,-0.47,1.132,,63.64,HHH,-1.17833,0.0495842,0.00492501,1.00609 beta-lactamase_625_L89Y,beta-lactamase_625_89,TEM-1,beta-lactamase_625,P62593,1.00609,NO,89,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.096,-4.101,3.005,,0.168,T,A,0.55,0.63,1.599,,64.34,PHO,-1.75767,0.213352,0.00207068,1.00609 beta-lactamase_156_D83K,beta-lactamase_156_83,TEM-1,beta-lactamase_156,P62593,1.0061,NO,83,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.066,-3.429,2.363,,0.354,H,A,0.75,0.22,1.281,,48.95,HAH,-1.34733,0.111618,0.00205968,1.0061 beta-lactamase_625_A278W,beta-lactamase_625_278,TEM-1,beta-lactamase_625,P62593,1.0061,NO,278,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.213352,0.0310297,1.0061 beta-lactamase_156_E35V,beta-lactamase_156_35,TEM-1,beta-lactamase_156,P62593,1.00611,NO,35,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-0.869,-3.578,2.709,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.111618,0.00174441,1.00611 beta-lactamase_2500_P25N,beta-lactamase_2500_25,TEM-1,beta-lactamase_2500,P62593,1.00611,NO,25,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.526,-3.702,2.176,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.361275,0.00347571,1.00611 beta-lactamase_39_S51I,beta-lactamase_39_51,TEM-1,beta-lactamase_39,P62593,1.00611,NO,51,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.526,-3.925,2.399,,0.496,T,A,0.27,0.26,2.964,,72.73,PPO,-1.88467,0.0495842,0.00504821,1.00611 beta-lactamase_625_Q37Y,beta-lactamase_625_37,TEM-1,beta-lactamase_625,P62593,1.00611,NO,37,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.134,-4.193,2.059,,0.613,H,A,0.64,1.98,1.318,,73.08,APH,-2.06967,0.213352,0.00425833,1.00611 beta-lactamase_R118T,beta-lactamase_118,TEM-1,beta-lactamase,P62593,1.00612,NO,118,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.413,-2.845,0.432,5.8227,0.457,H,A,0.68,1.39,2.144,,77.62,HBA,-1.785,0.221079,0.00538794,1.00612 Pab1_N187T,Pab1_187,Pab1,Pab1,P04147,1.00612,NO,187,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-1.224,-3.117,1.893,,0.456,S,b,,1.87,,,,HPO,-1.272,0.175299,0.00083165,1.00612 beta-lactamase_0_N152Y,beta-lactamase_0_152,TEM-1,beta-lactamase_0,P62593,1.00613,NO,152,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-2.757,-4.312,1.555,,0.863,H,A,0.61,0.92,2.151,,77.62,BPH,-2.97,0.0500837,0.00471429,1.00613 beta-lactamase_156_A170H,beta-lactamase_156_170,TEM-1,beta-lactamase_156,P62593,1.00613,NO,170,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.237,-4.694,3.457,,0.126,,L,0.46,-0.35,3.7,,64.69,AHH,-1.63267,0.111618,0.00431903,1.00613 beta-lactamase_39_M270Q,beta-lactamase_39_270,TEM-1,beta-lactamase_39,P62593,1.00613,NO,270,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.0495842,0.00767762,1.00613 beta-lactamase_625_S221G,beta-lactamase_625_221,TEM-1,beta-lactamase_625,P62593,1.00613,NO,221,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.754,-3.136,1.382,,0.624,H,A,0.27,-0.2,1.495,,74.48,BPH,-1.59967,0.213352,0.0046094,1.00613 beta-lactamase_A183A,beta-lactamase_183,TEM-1,beta-lactamase,P62593,1.00613,NO,183,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.231,-1.231,,4.84712,0.155,H,A,0.55,-0.91,12.189,,77.62,HHH,-1.53367,0.221079,0.00296631,1.00613 beta-lactamase_156_P224S,beta-lactamase_156_224,TEM-1,beta-lactamase_156,P62593,1.00614,NO,224,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.893,-2.58,1.687,,0.383,,B,0.52,-0.3,0.383,,74.48,HOH,-1.26433,0.111618,0.00189564,1.00614 beta-lactamase_156_S122I,beta-lactamase_156_122,TEM-1,beta-lactamase_156,P62593,1.00615,NO,122,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.406,-3.138,0.732,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.111618,0.00497825,1.00615 beta-lactamase_39_K32E,beta-lactamase_39_32,TEM-1,beta-lactamase_39,P62593,1.00615,NO,32,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.984,-2.418,0.434,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.0495842,0.00401283,1.00615 beta-lactamase_39_S266G,beta-lactamase_39_266,TEM-1,beta-lactamase_39,P62593,1.00615,NO,266,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.0495842,0.0140785,1.00615 beta-lactamase_625_D271I,beta-lactamase_625_271,TEM-1,beta-lactamase_625,P62593,1.00615,NO,271,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.213352,0.00752082,1.00615 beta-lactamase_625_R275C,beta-lactamase_625_275,TEM-1,beta-lactamase_625,P62593,1.00615,NO,275,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.213352,0.0141984,1.00615 beta-lactamase_2500_F58N,beta-lactamase_2500_58,TEM-1,beta-lactamase_2500,P62593,1.00617,NO,58,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-2.914,-3.795,0.881,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.361275,0.00523369,1.00617 beta-lactamase_156_T198E,beta-lactamase_156_198,TEM-1,beta-lactamase_156,P62593,1.00618,NO,198,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.168,-3.379,1.211,,0.489,,B,0.22,-0.13,10.771,10.771,73.78,HPH,-1.98767,0.111618,0.004311,1.00618 beta-lactamase_39_E195V,beta-lactamase_39_195,TEM-1,beta-lactamase_39,P62593,1.00618,NO,195,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.186,-3.798,1.612,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.0495842,0.00496565,1.00618 beta-lactamase_625_R92P,beta-lactamase_625_92,TEM-1,beta-lactamase_625,P62593,1.00618,NO,92,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.718,-3.033,1.315,,0.479,E,B,1.2,1.36,3.069,,65.38,BBH,-1.50367,0.213352,0.00429626,1.00618 beta-lactamase_L55I,beta-lactamase_55,TEM-1,beta-lactamase,P62593,1.00618,NO,55,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.86,-2.434,0.574,,0.372,E,A,1.07,-0.36,1.423,,63.99,HHA,-2.247,0.221079,0.00403741,1.00618 beta-lactamase_156_L38E,beta-lactamase_156_38,TEM-1,beta-lactamase_156,P62593,1.00619,NO,38,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.343,-3.797,2.454,,0.088,H,A,0.55,0.2,13.556,13.556,64.34,PHO,-1.78033,0.111618,0.00373244,1.00619 beta-lactamase_2500_E26H,beta-lactamase_2500_26,TEM-1,beta-lactamase_2500,P62593,1.00619,NO,26,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.454,-4.609,2.155,,0.54,H,A,1.04,0.98,0.49,,93.01,OAP,-1.96167,0.361275,0.00297948,1.00619 beta-lactamase_625_P255W,beta-lactamase_625_255,TEM-1,beta-lactamase_625,P62593,1.00619,NO,255,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.213352,0.00499612,1.00619 beta-lactamase_G39G,beta-lactamase_39,TEM-1,beta-lactamase,P62593,1.00619,NO,39,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.864,-1.864,,5.35574,0.701,T,L,0.23,0.47,29.926,29.926,77.62,HOH,-1.53633,0.221079,0.00487611,1.00619 E1_Ubiquitin_A46Q,E1_Ubiquitin_46,Uba1,E1_Ubiquitin,P0CG63,1.00619,NO,46,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.367,-3.873,2.506,,0.398,T,L,,-0.8,,,,HHO,-1.17167,0.18783,0.004233,1.00619 E1_Ubiquitin_L43F,E1_Ubiquitin_43,Uba1,E1_Ubiquitin,P0CG63,1.00619,NO,43,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.188,-3.58,2.392,,,E,B,,-1.17,,,,BHH,-1.30733,0.18783,0.00190185,1.00619 E1_Ubiquitin_L71W,E1_Ubiquitin_71,Uba1,E1_Ubiquitin,P0CG63,1.00619,NO,71,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.039,-4.915,3.876,,0.591,E,B,,-0.69,,,,BHB,-1.19433,0.18783,0.00148349,1.00619 E1_Ubiquitin_R42C,E1_Ubiquitin_42,Uba1,E1_Ubiquitin,P0CG63,1.00619,NO,42,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.302,-4.958,3.656,,0.244,E,B,,-0.54,,,,PBH,-1.24667,0.18783,0.00224033,1.00619 PSD95pdz3_F340Q,PSD95pdz3_340,PSD95pdz3,PSD95pdz3,P31016,1.00619,NO,340,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.524,-4.031,2.507,5.79283,,,,,11.8045,,,,PHH,-1.55767,0.0758425,0.000836987,1.00619 beta-lactamase_156_C75I,beta-lactamase_156_75,TEM-1,beta-lactamase_156,P62593,1.0062,NO,75,C,I,CI,Special,Hydrophobic,5.07,6.02,0.95,198,121,131,10,108.5,166.7,58.2,-1.245,-3.708,2.463,,,H,A,0.46,-0.87,0.876,,50,HOO,-1.24333,0.111618,0.0034616,1.0062 beta-lactamase_625_E108D,beta-lactamase_625_108,TEM-1,beta-lactamase_625,P62593,1.0062,NO,108,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.46,-2.67,1.21,,0.572,G,A,1.04,1.87,20.151,20.151,72.73,PAB,-1.437,0.213352,0.00413372,1.0062 Pab1_H134P,Pab1_134,Pab1,Pab1,P04147,1.0062,NO,134,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-1.542,-3.746,2.204,,,,,,,,,,HBO,-1.346,0.175299,0.00116356,1.0062 beta-lactamase_156_V72C,beta-lactamase_156_72,TEM-1,beta-lactamase_156,P62593,1.00621,NO,72,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.658,-4.8,3.142,,,H,A,0.44,-1.03,1.92,,65.73,BHH,-1.32167,0.111618,0.00501194,1.00621 beta-lactamase_625_M67V,beta-lactamase_625_67,TEM-1,beta-lactamase_625,P62593,1.00621,NO,67,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-2.231,-2.772,0.541,,0.006,G,P,0.55,-0.81,2.653,,65.03,HHP,-1.502,0.213352,0.00409753,1.00621 beta-lactamase_625_R41S,beta-lactamase_625_41,TEM-1,beta-lactamase_625,P62593,1.00621,NO,41,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-0.942,-2.526,1.584,,0.321,E,B,1.2,-0.07,1.186,,65.03,HBH,-1.30267,0.213352,0.00123327,1.00621 beta-lactamase_0_N98F,beta-lactamase_0_98,TEM-1,beta-lactamase_0,P62593,1.00622,NO,98,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-2.973,-3.271,0.298,,0.963,G,A,0.61,1.35,14.853,14.853,77.62,PPA,-2.07867,0.0500837,0.00505389,1.00622 beta-lactamase_156_A278K,beta-lactamase_156_278,TEM-1,beta-lactamase_156,P62593,1.00622,NO,278,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.111618,0.0310297,1.00622 beta-lactamase_156_E145N,beta-lactamase_156_145,TEM-1,beta-lactamase_156,P62593,1.00622,NO,145,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.357,-3.655,1.298,,0.545,H,A,1.04,0.79,3.661,,77.62,BAH,-2.069,0.111618,0.00553285,1.00622 beta-lactamase_T193I,beta-lactamase_193,TEM-1,beta-lactamase,P62593,1.00622,NO,193,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.914,-2.798,0.884,5.67952,0.439,H,a,0.3,0.33,1.863,,63.99,HPO,-1.52133,0.221079,0.00482669,1.00622 kka2_1:8_A25S,kka2_1:8_25,Kka2,kka2_1:8,P00552,1.00622,NO,25,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.496,-2.739,0.243,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.100394,0.00595636,1.00622 kka2_1:8_A25S,kka2_1:8_25,Kka2,kka2_1:8,P00552,1.00622,NO,25,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.496,-2.739,0.243,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.100394,0.00595636,1.00622 beta-lactamase_156_I171D,beta-lactamase_156_171,TEM-1,beta-lactamase_156,P62593,1.00623,NO,171,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-2.431,-3.888,1.457,,0.361,,B,0.48,0.53,3.869,,77.62,HHO,-1.55533,0.111618,0.00623355,1.00623 beta-lactamase_156_L160P,beta-lactamase_156_160,TEM-1,beta-lactamase_156,P62593,1.00623,NO,160,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.977,-4.121,3.144,,0.022,,B,0.55,-0.6,1.095,,44.41,BHA,-0.936,0.111618,0.00193775,1.00623 beta-lactamase_625_L167A,beta-lactamase_625_167,TEM-1,beta-lactamase_625,P62593,1.00623,NO,167,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.138,-3.097,1.959,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.213352,0.00303566,1.00623 beta-lactamase_2500_Q276A,beta-lactamase_2500_276,TEM-1,beta-lactamase_2500,P62593,1.00624,NO,276,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-1.144,-3.872,2.728,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.361275,0.0191712,1.00624 beta-lactamase_625_S80H,beta-lactamase_625_80,TEM-1,beta-lactamase_625,P62593,1.00624,NO,80,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.029,-3.359,1.33,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.213352,0.00565569,1.00624 beta-lactamase_K109E,beta-lactamase_109,TEM-1,beta-lactamase,P62593,1.00624,NO,109,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.734,-2.478,0.744,6.05842,0.787,G,A,1.82,2.21,21.623,21.623,72.73,ABB,-1.63333,0.221079,0.00462493,1.00624 beta-lactamase_156_L120C,beta-lactamase_156_120,TEM-1,beta-lactamase_156,P62593,1.00625,NO,120,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.044,-4.81,3.766,,,H,A,0.55,-1.13,7.813,,64.69,AHO,-1.13633,0.111618,0.00143563,1.00625 beta-lactamase_156_V260S,beta-lactamase_156_260,TEM-1,beta-lactamase_156,P62593,1.00625,NO,260,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.111618,0.00471757,1.00625 beta-lactamase_2500_R41H,beta-lactamase_2500_41,TEM-1,beta-lactamase_2500,P62593,1.00625,NO,41,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-0.942,-4.279,3.337,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.361275,0.00123327,1.00625 beta-lactamase_39_A123F,beta-lactamase_39_123,TEM-1,beta-lactamase_39,P62593,1.00625,NO,123,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.834,-4.065,3.231,,0.039,H,A,0.46,-0.72,0.705,,41.26,PHH,-1.47367,0.0495842,0.0010157,1.00625 beta-lactamase_39_L219G,beta-lactamase_39_219,TEM-1,beta-lactamase_39,P62593,1.00625,NO,219,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.313,-3.865,2.552,,,I,A,0.55,-0.51,19.842,19.842,74.48,HHB,-1.21533,0.0495842,0.00664345,1.00625 beta-lactamase_625_H151G,beta-lactamase_625_151,TEM-1,beta-lactamase_625,P62593,1.00625,NO,151,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-2.96,-2.515,-0.445,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.213352,0.00216946,1.00625 beta-lactamase_156_L28N,beta-lactamase_156_28,TEM-1,beta-lactamase_156,P62593,1.00626,NO,28,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.579,-4.056,2.477,,0.277,H,A,0.55,-0.16,3.262,,93.01,PHH,-2.11333,0.111618,0.00359321,1.00626 beta-lactamase_2500_A200R,beta-lactamase_2500_200,TEM-1,beta-lactamase_2500,P62593,1.00627,NO,200,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.878,-2.634,0.756,,0.757,H,A,0.46,-0.19,0.436,,77.62,HHP,-2.001,0.361275,0.0060056,1.00627 beta-lactamase_2500_E61Y,beta-lactamase_2500_61,TEM-1,beta-lactamase_2500,P62593,1.00627,NO,61,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.115,-4.403,2.288,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.361275,0.00440955,1.00627 beta-lactamase_39_T158S,beta-lactamase_39_158,TEM-1,beta-lactamase_39,P62593,1.00627,NO,158,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.116,-1.795,0.679,,0.036,,B,0.22,-0.85,2.755,,69.58,HPB,-1.269,0.0495842,0.00341825,1.00627 beta-lactamase_T107T,beta-lactamase_107,TEM-1,beta-lactamase,P62593,1.00628,NO,107,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.117,-1.117,,5.23432,,G,A,2.12,-0.06,3.676,,67.83,HPA,-1.265,0.221079,0.00239347,1.00628 beta-lactamase_156_R242T,beta-lactamase_156_242,TEM-1,beta-lactamase_156,P62593,1.00629,NO,242,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.111618,0.00452879,1.00629 beta-lactamase_2500_E108V,beta-lactamase_2500_108,TEM-1,beta-lactamase_2500,P62593,1.00629,NO,108,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.46,-3.706,2.246,,0.572,G,A,1.04,1.87,1.147,,72.73,PAB,-1.437,0.361275,0.00413372,1.00629 PSD95pdz3_K393N,PSD95pdz3_393,PSD95pdz3,PSD95pdz3,P31016,1.00629,NO,393,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.416,-3.13,1.714,5.42682,,,,,22.0122,,,,HBO,-1.4265,0.0758425,0.000879298,1.00629 beta-lactamase_156_F149S,beta-lactamase_156_149,TEM-1,beta-lactamase_156,P62593,1.0063,NO,149,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.299,-2.783,1.484,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.111618,0.00418462,1.0063 beta-lactamase_156_S201G,beta-lactamase_156_201,TEM-1,beta-lactamase_156,P62593,1.0063,NO,201,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.183,-2.39,1.207,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.111618,0.00198815,1.0063 beta-lactamase_625_T116Q,beta-lactamase_625_116,TEM-1,beta-lactamase_625,P62593,1.0063,NO,116,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.28,-3.898,2.618,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.213352,0.00336175,1.0063 beta-lactamase_M180A,beta-lactamase_180,TEM-1,beta-lactamase,P62593,1.0063,NO,180,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-2.795,-2.974,0.179,4.96809,0.242,,B,1.07,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.221079,0.00552048,1.0063 kka2_1:1_S114R,kka2_1:1_114,Kka2,kka2_1:1,P00552,1.0063,NO,114,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.527,-2.846,0.319,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.520039,0.00705262,1.0063 beta-lactamase_156_L100H,beta-lactamase_156_100,TEM-1,beta-lactamase_156,P62593,1.00631,NO,100,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.218,-4.855,3.637,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.111618,0.00413885,1.00631 beta-lactamase_625_V29H,beta-lactamase_625_29,TEM-1,beta-lactamase_625,P62593,1.00631,NO,29,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-2.856,-4.571,1.715,,0.733,H,A,0.44,-0.78,1.931,,93.01,HHB,-2.24733,0.213352,0.00318969,1.00631 gb1_A252S,gb1_252,gb1,gb1,P06654,1.00631,NO,252,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.175,-2.671,1.496,,,,,,,,,,PHA,-1.55967,0.177985,0.00125598,1.00631 beta-lactamase_156_F228M,beta-lactamase_156_228,TEM-1,beta-lactamase_156,P62593,1.00632,NO,228,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-2.342,-3.369,1.027,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.111618,0.0046669,1.00632 beta-lactamase_156_L196F,beta-lactamase_156_196,TEM-1,beta-lactamase_156,P62593,1.00632,NO,196,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-2.478,-4.226,1.748,,0.518,S,A,0.55,1.35,7.897,,77.62,AHH,-1.839,0.111618,0.00512144,1.00632 beta-lactamase_156_S256I,beta-lactamase_156_256,TEM-1,beta-lactamase_156,P62593,1.00632,NO,256,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.621,-3.676,2.055,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.111618,0.00710634,1.00632 beta-lactamase_39_A222T,beta-lactamase_39_222,TEM-1,beta-lactamase_39,P62593,1.00632,NO,222,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.103,-2.805,0.702,,0.233,H,A,0.46,-0.25,1.448,,77.62,PHH,-1.63733,0.0495842,0.00466094,1.00632 beta-lactamase_39_L196Q,beta-lactamase_39_196,TEM-1,beta-lactamase_39,P62593,1.00632,NO,196,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-2.478,-3.242,0.764,,0.518,S,A,0.55,1.35,12.152,12.152,77.62,AHH,-1.839,0.0495842,0.00512144,1.00632 beta-lactamase_39_T126E,beta-lactamase_39_126,TEM-1,beta-lactamase_39,P62593,1.00632,NO,126,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.122,-3.395,2.273,,0.05,H,A,0.22,-0.05,0.586,,44.41,HPH,-1.60467,0.0495842,0.00244552,1.00632 beta-lactamase_156_A77N,beta-lactamase_156_77,TEM-1,beta-lactamase_156,P62593,1.00633,NO,77,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.234,-3.844,2.61,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.111618,0.00282362,1.00633 beta-lactamase_39_N274I,beta-lactamase_39_274,TEM-1,beta-lactamase_39,P62593,1.00633,NO,274,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.0495842,0.0110418,1.00633 beta-lactamase_39_T107I,beta-lactamase_39_107,TEM-1,beta-lactamase_39,P62593,1.00633,NO,107,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.117,-3.664,2.547,,,G,A,0.22,-0.06,2.686,,67.83,HPA,-1.265,0.0495842,0.00239347,1.00633 beta-lactamase_P172A,beta-lactamase_172,TEM-1,beta-lactamase,P62593,1.00633,NO,172,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.998,-2.44,1.442,5.98941,0.639,T,b,1.1,0.24,2.087,,74.48,HOP,-2.03067,0.221079,0.00312594,1.00633 beta-lactamase_156_S122R,beta-lactamase_156_122,TEM-1,beta-lactamase_156,P62593,1.00634,NO,122,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.406,-3.131,0.725,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.111618,0.00497825,1.00634 beta-lactamase_39_G265K,beta-lactamase_39_265,TEM-1,beta-lactamase_39,P62593,1.00634,NO,265,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.0495842,0.00811926,1.00634 beta-lactamase_39_T147A,beta-lactamase_39_147,TEM-1,beta-lactamase_39,P62593,1.00634,NO,147,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.149,-2.982,1.833,,0.281,H,A,0.22,-0.68,13.843,13.843,64.34,HPH,-1.456,0.0495842,0.00226017,1.00634 beta-lactamase_625_L79M,beta-lactamase_625_79,TEM-1,beta-lactamase_625,P62593,1.00634,NO,79,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.842,-2.761,1.919,,0.007,H,A,0.55,-0.16,0.935,,50.35,HHP,-1.44333,0.213352,0.000947397,1.00634 PSD95pdz3_A378M,PSD95pdz3_378,PSD95pdz3,PSD95pdz3,P31016,1.00634,NO,378,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.307,-4.162,2.855,4.86582,,,,,14.576,,,,HHH,-1.509,0.0758425,0.000313169,1.00634 beta-lactamase_2500_N152R,beta-lactamase_2500_152,TEM-1,beta-lactamase_2500,P62593,1.00635,NO,152,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-2.757,-2.835,0.078,,0.863,H,A,0.61,0.92,2.061,,77.62,BPH,-2.97,0.361275,0.00471429,1.00635 beta-lactamase_39_V29L,beta-lactamase_39_29,TEM-1,beta-lactamase_39,P62593,1.00635,NO,29,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-2.856,-3.547,0.691,,0.733,H,A,0.44,-0.78,1.287,,93.01,HHB,-2.24733,0.0495842,0.00318969,1.00635 beta-lactamase_625_R91A,beta-lactamase_625_91,TEM-1,beta-lactamase_625,P62593,1.00635,NO,91,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.392,-2.55,1.158,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.213352,0.00380226,1.00635 beta-lactamase_156_W163M,beta-lactamase_156_163,TEM-1,beta-lactamase_156,P62593,1.00636,NO,163,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-1.843,-3.104,1.261,,0.467,,B,0.47,-0.5,15.095,15.095,63.99,BHA,-1.269,0.111618,0.00418955,1.00636 beta-lactamase_39_L199F,beta-lactamase_39_199,TEM-1,beta-lactamase_39,P62593,1.00636,NO,199,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-2.942,-4.403,1.461,,0.832,H,A,0.55,0.42,15.504,15.504,77.62,PHH,-2.32933,0.0495842,0.0048649,1.00636 beta-lactamase_39_T147G,beta-lactamase_39_147,TEM-1,beta-lactamase_39,P62593,1.00636,NO,147,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.149,-2.499,1.35,,0.281,H,A,0.22,-0.68,13.843,13.843,64.34,HPH,-1.456,0.0495842,0.00226017,1.00636 kka2_1:8_N58S,kka2_1:8_58,Kka2,kka2_1:8,P00552,1.00636,NO,58,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-2.641,-1.901,-0.74,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.100394,0.00793425,1.00636 kka2_1:8_N58S,kka2_1:8_58,Kka2,kka2_1:8,P00552,1.00636,NO,58,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-2.641,-1.901,-0.74,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.100394,0.00793425,1.00636 beta-lactamase_0_D271Q,beta-lactamase_0_271,TEM-1,beta-lactamase_0,P62593,1.00637,NO,271,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.0500837,0.00752082,1.00637 beta-lactamase_156_L196S,beta-lactamase_156_196,TEM-1,beta-lactamase_156,P62593,1.00637,NO,196,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-2.478,-2.752,0.274,,0.518,S,A,0.55,1.35,7.897,,77.62,AHH,-1.839,0.111618,0.00512144,1.00637 beta-lactamase_625_L73V,beta-lactamase_625_73,TEM-1,beta-lactamase_625,P62593,1.00637,NO,73,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.507,-2.286,0.779,,,H,A,0.55,-0.64,2.933,,67.83,HHH,-1.487,0.213352,0.00488983,1.00637 beta-lactamase_625_L89V,beta-lactamase_625_89,TEM-1,beta-lactamase_625,P62593,1.00637,NO,89,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.096,-3.043,1.947,,0.168,T,A,0.55,0.63,1.599,,64.34,PHO,-1.75767,0.213352,0.00207068,1.00637 beta-lactamase_H151Y,beta-lactamase_151,TEM-1,beta-lactamase,P62593,1.00637,NO,151,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-2.96,-4.115,1.155,5.47408,0.594,H,A,0.35,0.1,1.843,,77.62,HBP,-2.34767,0.221079,0.00216946,1.00637 beta-lactamase_H94K,beta-lactamase_94,TEM-1,beta-lactamase,P62593,1.00637,NO,94,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-2.5,-2.567,0.067,6.1507,0.776,,B,0.63,1.24,1.176,,77.62,HBH,-1.872,0.221079,0.00389226,1.00637 beta-lactamase_156_T107I,beta-lactamase_156_107,TEM-1,beta-lactamase_156,P62593,1.00638,NO,107,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.117,-3.664,2.547,,,G,A,0.22,-0.06,0.341,,67.83,HPA,-1.265,0.111618,0.00239347,1.00638 beta-lactamase_39_I277M,beta-lactamase_39_277,TEM-1,beta-lactamase_39,P62593,1.00638,NO,277,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.0495842,0.0169305,1.00638 beta-lactamase_39_M127L,beta-lactamase_39_127,TEM-1,beta-lactamase_39,P62593,1.00638,NO,127,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-2.251,-2.123,-0.128,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.0495842,0.00437927,1.00638 beta-lactamase_625_Q37W,beta-lactamase_625_37,TEM-1,beta-lactamase_625,P62593,1.00638,NO,37,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.134,-3.439,1.305,,0.613,H,A,0.64,1.98,1.318,,73.08,APH,-2.06967,0.213352,0.00425833,1.00638 beta-lactamase_E169G,beta-lactamase_169,TEM-1,beta-lactamase,P62593,1.00638,NO,169,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.23,-3.348,2.118,5.78896,0.337,,A,0.52,1,1.806,,73.08,PAH,-1.16533,0.221079,0.00400994,1.00638 kka2_1:8_V84S,kka2_1:8_84,Kka2,kka2_1:8,P00552,1.00638,NO,84,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-2.279,-2.917,0.638,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.100394,0.00724019,1.00638 kka2_1:8_V84S,kka2_1:8_84,Kka2,kka2_1:8,P00552,1.00638,NO,84,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-2.279,-2.917,0.638,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.100394,0.00724019,1.00638 beta-lactamase_2500_V29Q,beta-lactamase_2500_29,TEM-1,beta-lactamase_2500,P62593,1.00639,NO,29,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-2.856,-2.926,0.07,,0.733,H,A,0.44,-0.78,1.931,,93.01,HHB,-2.24733,0.361275,0.00318969,1.00639 beta-lactamase_39_K53C,beta-lactamase_39_53,TEM-1,beta-lactamase_39,P62593,1.00639,NO,53,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-2.313,-5.135,2.822,,0.589,,B,2.34,1.15,15.633,15.633,77.62,OBH,-2.1,0.0495842,0.00383383,1.00639 beta-lactamase_39_S104V,beta-lactamase_39_104,TEM-1,beta-lactamase_39,P62593,1.00639,NO,104,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.015,-3.487,2.472,,0.04,,b,0.27,0.57,4.02,,63.29,HPO,-1.05267,0.0495842,0.00218083,1.00639 beta-lactamase_625_A183G,beta-lactamase_625_183,TEM-1,beta-lactamase_625,P62593,1.00639,NO,183,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.231,-3.077,1.846,,0.155,H,A,0.46,-0.91,23.859,23.859,77.62,HHH,-1.53367,0.213352,0.00296631,1.00639 beta-lactamase_625_A222D,beta-lactamase_625_222,TEM-1,beta-lactamase_625,P62593,1.00639,NO,222,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.103,-3.723,1.62,,0.233,H,A,0.46,-0.25,1.448,,77.62,PHH,-1.63733,0.213352,0.00466094,1.00639 beta-lactamase_625_M270V,beta-lactamase_625_270,TEM-1,beta-lactamase_625,P62593,1.00639,NO,270,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.213352,0.00767762,1.00639 beta-lactamase_156_M66A,beta-lactamase_156_66,TEM-1,beta-lactamase_156,P62593,1.0064,NO,66,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.362,-3.154,1.792,,0.013,,A,0.55,-0.7,1.94,,73.08,OHH,-1.49567,0.111618,0.00412876,1.0064 beta-lactamase_625_D212P,beta-lactamase_625_212,TEM-1,beta-lactamase_625,P62593,1.0064,NO,212,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.624,-3.916,2.292,,0.037,,b,0.75,-0.58,1.516,,74.48,HAB,-1.77667,0.213352,0.00644302,1.0064 PSD95pdz3_R354F,PSD95pdz3_354,PSD95pdz3,PSD95pdz3,P31016,1.0064,NO,354,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.582,-3.974,2.392,6.21887,,,,,23.7791,,,,HBB,-1.44833,0.0758425,0.000650924,1.0064 beta-lactamase_0_P60F,beta-lactamase_0_60,TEM-1,beta-lactamase_0,P62593,1.00641,NO,60,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-2.469,-4.292,1.823,,0.256,T,A,0.52,-0.56,3.653,,77.62,BOA,-1.97633,0.0500837,0.00521318,1.00641 beta-lactamase_156_A182Y,beta-lactamase_156_182,TEM-1,beta-lactamase_156,P62593,1.00641,NO,182,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.777,-4.299,2.522,,0.136,H,A,0.46,-0.66,16.784,16.784,93.01,OHH,-1.27367,0.111618,0.00559099,1.00641 beta-lactamase_156_I277Y,beta-lactamase_156_277,TEM-1,beta-lactamase_156,P62593,1.00641,NO,277,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.111618,0.0169305,1.00641 beta-lactamase_156_I54T,beta-lactamase_156_54,TEM-1,beta-lactamase_156,P62593,1.00641,NO,54,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-2.838,-2.043,-0.795,,0.669,E,B,0.48,-0.14,0.541,,73.78,BHH,-2.337,0.111618,0.00403589,1.00641 beta-lactamase_39_M66L,beta-lactamase_39_66,TEM-1,beta-lactamase_39,P62593,1.00641,NO,66,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.362,-1.674,0.312,,0.013,,A,0.55,-0.7,1.319,,73.08,OHH,-1.49567,0.0495842,0.00412876,1.00641 beta-lactamase_M67C,beta-lactamase_67,TEM-1,beta-lactamase,P62593,1.00641,NO,67,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-2.231,-2.364,0.133,4.9618,0.006,G,P,1.07,-0.81,1.463,,65.03,HHP,-1.502,0.221079,0.00409753,1.00641 beta-lactamase_0_V72F,beta-lactamase_0_72,TEM-1,beta-lactamase_0,P62593,1.00642,NO,72,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.658,-3.023,1.365,,,H,A,0.44,-1.03,2.964,,65.73,BHH,-1.32167,0.0500837,0.00501194,1.00642 beta-lactamase_156_S104R,beta-lactamase_156_104,TEM-1,beta-lactamase_156,P62593,1.00642,NO,104,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.015,-3.804,2.789,,0.04,,b,0.27,0.57,4.02,,63.29,HPO,-1.05267,0.111618,0.00218083,1.00642 beta-lactamase_2500_A183Q,beta-lactamase_2500_183,TEM-1,beta-lactamase_2500,P62593,1.00642,NO,183,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.231,-3.932,2.701,,0.155,H,A,0.46,-0.91,12.189,,77.62,HHH,-1.53367,0.361275,0.00296631,1.00642 beta-lactamase_2500_E169M,beta-lactamase_2500_169,TEM-1,beta-lactamase_2500,P62593,1.00642,NO,169,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.23,-4.676,3.446,,0.337,,A,1.04,1,1.806,,73.08,PAH,-1.16533,0.361275,0.00400994,1.00642 beta-lactamase_625_A148R,beta-lactamase_625_148,TEM-1,beta-lactamase_625,P62593,1.00642,NO,148,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.757,-2.456,0.699,,0.379,H,A,0.46,-0.55,1.359,,72.73,PHH,-1.40167,0.213352,0.00547053,1.00642 beta-lactamase_625_L100F,beta-lactamase_625_100,TEM-1,beta-lactamase_625,P62593,1.00642,NO,100,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.218,-3.677,2.459,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.213352,0.00413885,1.00642 beta-lactamase_625_S122A,beta-lactamase_625_122,TEM-1,beta-lactamase_625,P62593,1.00642,NO,122,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.406,-2.18,-0.226,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.213352,0.00497825,1.00642 beta-lactamase_39_G52C,beta-lactamase_39_52,TEM-1,beta-lactamase_39,P62593,1.00643,NO,52,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.149,-5.084,3.935,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.0495842,0.00340138,1.00643 beta-lactamase_39_K30P,beta-lactamase_39_30,TEM-1,beta-lactamase_39,P62593,1.00643,NO,30,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-2.307,-3.871,1.564,,0.142,H,A,2.34,-0.65,6.717,,93.01,HBH,-2.32833,0.0495842,0.00448593,1.00643 beta-lactamase_39_P65A,beta-lactamase_39_65,TEM-1,beta-lactamase_39,P62593,1.00643,NO,65,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.894,-3.096,2.202,,0.098,E,B,0.52,-0.62,0.623,,40.56,HOH,-1.03233,0.0495842,0.00152776,1.00643 beta-lactamase_156_D113Y,beta-lactamase_156_113,TEM-1,beta-lactamase_156,P62593,1.00644,NO,113,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.829,-4.441,2.612,,0.665,T,A,0.75,0.91,2.973,,73.08,PAO,-1.703,0.111618,0.00474112,1.00644 beta-lactamase_156_E108L,beta-lactamase_156_108,TEM-1,beta-lactamase_156,P62593,1.00644,NO,108,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.46,-3.653,2.193,,0.572,G,A,1.04,1.87,8.602,8.602,72.73,PAB,-1.437,0.111618,0.00413372,1.00644 beta-lactamase_156_N173A,beta-lactamase_156_173,TEM-1,beta-lactamase_156,P62593,1.00644,NO,173,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-2.663,-2.432,-0.231,,1.044,T,l,0.61,1.25,3.718,,77.62,OPA,-1.46633,0.111618,0.0033769,1.00644 beta-lactamase_2500_A183S,beta-lactamase_2500_183,TEM-1,beta-lactamase_2500,P62593,1.00644,NO,183,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.231,-2.011,0.78,,0.155,H,A,0.46,-0.91,12.189,,77.62,HHH,-1.53367,0.361275,0.00296631,1.00644 beta-lactamase_39_N173S,beta-lactamase_39_173,TEM-1,beta-lactamase_39,P62593,1.00644,NO,173,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-2.663,-3.203,0.54,,1.044,T,l,0.61,1.25,1.426,,77.62,OPA,-1.46633,0.0495842,0.0033769,1.00644 beta-lactamase_39_P25Q,beta-lactamase_39_25,TEM-1,beta-lactamase_39,P62593,1.00644,NO,25,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.526,-2.522,0.996,,0.624,H,A,0.52,0.14,1.157,,73.08,BOA,-2.15367,0.0495842,0.00347571,1.00644 beta-lactamase_625_G141D,beta-lactamase_625_141,TEM-1,beta-lactamase_625,P62593,1.00644,NO,141,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.828,-2.284,1.456,,0.575,T,l,0.29,-0.28,0.198,,64.69,HOO,-1.08933,0.213352,0.0012419,1.00644 beta-lactamase_2500_E238L,beta-lactamase_2500_238,TEM-1,beta-lactamase_2500,P62593,1.00645,NO,238,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.361275,0.00743256,1.00645 beta-lactamase_2500_L47V,beta-lactamase_2500_47,TEM-1,beta-lactamase_2500,P62593,1.00645,NO,47,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.876,-2.564,0.688,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.361275,0.00439844,1.00645 beta-lactamase_2500_Q267G,beta-lactamase_2500_267,TEM-1,beta-lactamase_2500,P62593,1.00645,NO,267,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.361275,0.0102128,1.00645 beta-lactamase_625_A282K,beta-lactamase_625_282,TEM-1,beta-lactamase_625,P62593,1.00645,NO,282,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.213352,0.0449821,1.00645 beta-lactamase_625_Y95W,beta-lactamase_625_95,TEM-1,beta-lactamase_625,P62593,1.00645,NO,95,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-1.715,-3.22,1.505,,0.122,,b,0.21,-0.37,3.355,,77.62,BHP,-2.16167,0.213352,0.00479449,1.00645 beta-lactamase_0_L160T,beta-lactamase_0_160,TEM-1,beta-lactamase_0,P62593,1.00646,NO,160,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.977,-3.438,2.461,,0.022,,B,0.55,-0.6,0.68,,44.41,BHA,-0.936,0.0500837,0.00193775,1.00646 beta-lactamase_2500_Q97V,beta-lactamase_2500_97,TEM-1,beta-lactamase_2500,P62593,1.00646,NO,97,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.072,-3.633,1.561,,0.823,G,A,0.64,2.42,1.157,,77.62,PPP,-2.43833,0.361275,0.0045116,1.00646 beta-lactamase_625_E56D,beta-lactamase_625_56,TEM-1,beta-lactamase_625,P62593,1.00646,NO,56,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.043,-3.248,1.205,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.213352,0.00238534,1.00646 beta-lactamase_L196V,beta-lactamase_196,TEM-1,beta-lactamase,P62593,1.00646,NO,196,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-2.478,-2.258,-0.22,,0.518,S,A,0.55,1.35,,,77.62,AHH,-1.839,0.221079,0.00512144,1.00646 kka2_1:8_A64T,kka2_1:8_64,Kka2,kka2_1:8,P00552,1.00646,NO,64,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.496,-2.834,1.338,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.100394,0.00705578,1.00646 kka2_1:8_A64T,kka2_1:8_64,Kka2,kka2_1:8,P00552,1.00646,NO,64,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.496,-2.834,1.338,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.100394,0.00705578,1.00646 beta-lactamase_0_E61C,beta-lactamase_0_61,TEM-1,beta-lactamase_0,P62593,1.00647,NO,61,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.115,-5.186,3.071,,0.775,T,a,1.04,1.29,34.763,34.763,77.62,OAA,-1.92567,0.0500837,0.00440955,1.00647 beta-lactamase_0_V78K,beta-lactamase_0_78,TEM-1,beta-lactamase_0,P62593,1.00647,NO,78,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.459,-3.849,2.39,,,H,A,0.44,-0.47,16.615,16.615,63.64,HHH,-1.17833,0.0500837,0.00492501,1.00647 beta-lactamase_39_L135F,beta-lactamase_39_135,TEM-1,beta-lactamase_39,P62593,1.00647,NO,135,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.002,-3.671,2.669,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.0495842,0.00244423,1.00647 beta-lactamase_39_L205W,beta-lactamase_39_205,TEM-1,beta-lactamase_39,P62593,1.00647,NO,205,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.922,-4.959,4.037,,,H,A,0.55,-0.46,0.846,,42.31,PHH,-1.57767,0.0495842,0.00255802,1.00647 beta-lactamase_625_A211S,beta-lactamase_625_211,TEM-1,beta-lactamase_625,P62593,1.00647,NO,211,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.896,-2.788,0.892,,0.369,T,A,0.46,-0.69,2.061,,77.62,AHA,-1.94633,0.213352,0.00648183,1.00647 kka2_1:4_E86G,kka2_1:4_86,Kka2,kka2_1:4,P00552,1.00647,NO,86,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.86,-2.302,0.442,,0.369,.,B,1.04,1.92,4.451,,63.26,PAH,-1.98067,0.168804,0.00642858,1.00647 kka2_1:8_A65Y,kka2_1:8_65,Kka2,kka2_1:8,P00552,1.00647,NO,65,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.744,-4.354,2.61,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.100394,0.00709258,1.00647 kka2_1:8_A65Y,kka2_1:8_65,Kka2,kka2_1:8,P00552,1.00647,NO,65,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.744,-4.354,2.61,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.100394,0.00709258,1.00647 beta-lactamase_156_E61D,beta-lactamase_156_61,TEM-1,beta-lactamase_156,P62593,1.00648,NO,61,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.115,-1.402,-0.713,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.111618,0.00440955,1.00648 beta-lactamase_156_T126D,beta-lactamase_156_126,TEM-1,beta-lactamase_156,P62593,1.00648,NO,126,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.122,-2.344,1.222,,0.05,H,A,0.22,-0.05,1.14,,44.41,HPH,-1.60467,0.111618,0.00244552,1.00648 beta-lactamase_39_G85Q,beta-lactamase_39_85,TEM-1,beta-lactamase_39,P62593,1.00648,NO,85,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.011,-3.928,2.917,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.0495842,0.00252173,1.00648 beta-lactamase_625_A247F,beta-lactamase_625_247,TEM-1,beta-lactamase_625,P62593,1.00648,NO,247,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.213352,0.00611275,1.00648 beta-lactamase_625_K286R,beta-lactamase_625_286,TEM-1,beta-lactamase_625,P62593,1.00648,NO,286,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.213352,,1.00648 beta-lactamase_156_E108G,beta-lactamase_156_108,TEM-1,beta-lactamase_156,P62593,1.00649,NO,108,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.46,-2.454,0.994,,0.572,G,A,1.04,1.87,8.602,8.602,72.73,PAB,-1.437,0.111618,0.00413372,1.00649 beta-lactamase_39_P255S,beta-lactamase_39_255,TEM-1,beta-lactamase_39,P62593,1.00649,NO,255,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.0495842,0.00499612,1.00649 beta-lactamase_39_V214I,beta-lactamase_39_214,TEM-1,beta-lactamase_39,P62593,1.00649,NO,214,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.299,-3.053,1.754,,0.375,S,A,0.44,-0.44,18.838,18.838,74.48,BHH,-1.53733,0.0495842,0.00628442,1.00649 beta-lactamase_156_R189Q,beta-lactamase_156_189,TEM-1,beta-lactamase_156,P62593,1.0065,NO,189,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.844,-2.262,0.418,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.111618,0.0050699,1.0065 Pab1_L186V,Pab1_186,Pab1,Pab1,P04147,1.0065,NO,186,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.783,-1.525,-0.258,,,,,,,,,,HHP,-1.56967,0.175299,0.00154968,1.0065 beta-lactamase_156_A148K,beta-lactamase_156_148,TEM-1,beta-lactamase_156,P62593,1.00652,NO,148,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.757,-2.857,1.1,,0.379,H,A,0.46,-0.55,3.551,,72.73,PHH,-1.40167,0.111618,0.00547053,1.00652 beta-lactamase_156_L74V,beta-lactamase_156_74,TEM-1,beta-lactamase_156,P62593,1.00652,NO,74,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.296,-2.972,1.676,,,H,A,0.55,-0.91,0.746,,50,HHO,-1.34933,0.111618,0.00493255,1.00652 beta-lactamase_625_A278R,beta-lactamase_625_278,TEM-1,beta-lactamase_625,P62593,1.00652,NO,278,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.213352,0.0310297,1.00652 beta-lactamase_625_T126N,beta-lactamase_625_126,TEM-1,beta-lactamase_625,P62593,1.00652,NO,126,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.122,-3.467,2.345,,0.05,H,A,0.22,-0.05,0.817,,44.41,HPH,-1.60467,0.213352,0.00244552,1.00652 Pab1_T145A,Pab1_145,Pab1,Pab1,P04147,1.00652,NO,145,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.067,-2.67,1.603,,0.237,H,A,0.3,0.69,,,,APH,-1.135,0.175299,0.000331088,1.00652 PSD95pdz3_V386T,PSD95pdz3_386,PSD95pdz3,PSD95pdz3,P31016,1.00652,NO,386,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.465,-2.878,1.413,5.18836,,,,,17.5429,,,,PHP,-1.463,0.0758425,0.000184509,1.00652 beta-lactamase_156_A182V,beta-lactamase_156_182,TEM-1,beta-lactamase_156,P62593,1.00653,NO,182,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.777,-2.556,0.779,,0.136,H,A,0.46,-0.66,16.784,16.784,93.01,OHH,-1.27367,0.111618,0.00559099,1.00653 beta-lactamase_156_L38W,beta-lactamase_156_38,TEM-1,beta-lactamase_156,P62593,1.00653,NO,38,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.343,-5.229,3.886,,0.088,H,A,0.55,0.2,13.556,13.556,64.34,PHO,-1.78033,0.111618,0.00373244,1.00653 beta-lactamase_156_P105R,beta-lactamase_156_105,TEM-1,beta-lactamase_156,P62593,1.00653,NO,105,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.813,-3.93,3.117,,0.226,T,A,0.52,0.8,1.154,,63.29,POH,-1.01533,0.111618,0.0011981,1.00653 beta-lactamase_2500_R118Y,beta-lactamase_2500_118,TEM-1,beta-lactamase_2500,P62593,1.00653,NO,118,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.413,-4.398,1.985,,0.457,H,A,1.2,1.39,2.144,,77.62,HBA,-1.785,0.361275,0.00538794,1.00653 beta-lactamase_625_L49W,beta-lactamase_625_49,TEM-1,beta-lactamase_625,P62593,1.00653,NO,49,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.897,-5.315,3.418,,0.131,T,A,0.55,0.04,3.112,,64.69,AHP,-1.99233,0.213352,0.00401477,1.00653 beta-lactamase_A276H,beta-lactamase_276,TEM-1,beta-lactamase,P62593,1.00653,NO,276,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.144,-4.666,3.522,5.1387,0.117,H,A,0.52,-0.84,1.283,,44.06,HHA,-1.47,0.221079,0.0191712,1.00653 beta-lactamase_F13A,beta-lactamase_13,TEM-1,beta-lactamase,P62593,1.00653,NO,13,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-2.394,-3.082,0.688,,,,,,,4.079,,77.62,OHH,-2.382,0.221079,0.0029078,1.00653 beta-lactamase_I45F,beta-lactamase_45,TEM-1,beta-lactamase,P62593,1.00653,NO,45,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-2.421,-3.147,0.726,5.31505,,E,B,1,-0.3,2.256,,77.62,HHA,-2.30267,0.221079,0.00452842,1.00653 beta-lactamase_V8L,beta-lactamase_8,TEM-1,beta-lactamase,P62593,1.00653,NO,8,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-2.358,-1.553,-0.805,,,,,,,0.575,,77.62,BHH,-2.06267,0.221079,0.00226401,1.00653 beta-lactamase_39_D212R,beta-lactamase_39_212,TEM-1,beta-lactamase_39,P62593,1.00654,NO,212,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.624,-3.921,2.297,,0.037,,b,0.75,-0.58,10.748,10.748,74.48,HAB,-1.77667,0.0495842,0.00644302,1.00654 beta-lactamase_39_L47Y,beta-lactamase_39_47,TEM-1,beta-lactamase_39,P62593,1.00655,NO,47,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.876,-3.117,1.241,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.0495842,0.00439844,1.00655 beta-lactamase_39_L55R,beta-lactamase_39_55,TEM-1,beta-lactamase_39,P62593,1.00655,NO,55,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.86,-3.1,1.24,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.0495842,0.00403741,1.00655 beta-lactamase_625_A182F,beta-lactamase_625_182,TEM-1,beta-lactamase_625,P62593,1.00655,NO,182,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.777,-4.357,2.58,,0.136,H,A,0.46,-0.66,16.784,16.784,93.01,OHH,-1.27367,0.213352,0.00559099,1.00655 beta-lactamase_625_G194K,beta-lactamase_625_194,TEM-1,beta-lactamase_625,P62593,1.00655,NO,194,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.396,-3.557,2.161,,0.276,S,b,0.29,0.36,3.593,,67.83,POA,-1.832,0.213352,0.00392163,1.00655 PSD95pdz3_L349F,PSD95pdz3_349,PSD95pdz3,PSD95pdz3,P31016,1.00655,NO,349,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.347,-3.299,1.952,5.14696,,,,,24.6438,,,,AHP,-1.37667,0.0758425,0.00071841,1.00655 beta-lactamase_156_A34S,beta-lactamase_156_34,TEM-1,beta-lactamase_156,P62593,1.00656,NO,34,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.059,-2.213,0.154,,,H,A,0.46,-0.54,3.614,,73.78,AHA,-1.74967,0.111618,0.00407913,1.00656 beta-lactamase_156_N274D,beta-lactamase_156_274,TEM-1,beta-lactamase_156,P62593,1.00656,NO,274,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.111618,0.0110418,1.00656 beta-lactamase_39_K109D,beta-lactamase_39_109,TEM-1,beta-lactamase_39,P62593,1.00656,NO,109,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.734,-2.919,1.185,,0.787,G,A,2.34,2.21,7.243,,72.73,ABB,-1.63333,0.0495842,0.00462493,1.00656 beta-lactamase_E175L,beta-lactamase_175,TEM-1,beta-lactamase,P62593,1.00656,NO,175,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.336,-3.444,1.108,6.0311,0.551,,A,0.75,1.05,5.316,,77.62,AAB,-1.31233,0.221079,0.00482205,1.00656 beta-lactamase_156_R275Q,beta-lactamase_156_275,TEM-1,beta-lactamase_156,P62593,1.00657,NO,275,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.111618,0.0141984,1.00657 beta-lactamase_156_T186I,beta-lactamase_156_186,TEM-1,beta-lactamase_156,P62593,1.00657,NO,186,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.522,-3.94,1.418,,0.396,H,A,0.22,-0.28,16.606,16.606,77.62,HPP,-1.77633,0.111618,0.00485034,1.00657 beta-lactamase_39_E46V,beta-lactamase_39_46,TEM-1,beta-lactamase_39,P62593,1.00657,NO,46,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.94,-1.834,-0.106,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.0495842,0.00427568,1.00657 beta-lactamase_625_S96I,beta-lactamase_625_96,TEM-1,beta-lactamase_625,P62593,1.00657,NO,96,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.27,-3.225,0.955,,0.368,,b,0.27,0.39,5.244,,73.78,HPP,-2.019,0.213352,0.00551835,1.00657 beta-lactamase_156_L150S,beta-lactamase_156_150,TEM-1,beta-lactamase_156,P62593,1.00658,NO,150,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.326,-3.477,2.151,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.111618,0.00463171,1.00658 beta-lactamase_156_P217W,beta-lactamase_156_217,TEM-1,beta-lactamase_156,P62593,1.00658,NO,217,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-2.062,-5.565,3.503,,0.496,I,A,0.52,-0.33,2.303,,74.48,OOH,-1.64333,0.111618,0.00463211,1.00658 beta-lactamase_625_C75T,beta-lactamase_625_75,TEM-1,beta-lactamase_625,P62593,1.00658,NO,75,C,T,CT,Special,Polar,5.07,5.6,0.53,149,121,119,-2,108.5,116.1,7.6,-1.245,-3.423,2.178,,,H,A,0.46,-0.87,2.141,,50,HOO,-1.24333,0.213352,0.0034616,1.00658 beta-lactamase_625_D36G,beta-lactamase_625_36,TEM-1,beta-lactamase_625,P62593,1.00658,NO,36,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.732,-2.829,0.097,,0.555,H,A,0.75,1.17,2.26,,77.62,AAP,-1.91167,0.213352,0.00476483,1.00658 PSD95pdz3_G383S,PSD95pdz3_383,PSD95pdz3,PSD95pdz3,P31016,1.00658,NO,383,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.008,-2.842,1.834,5.17213,,,,,20.5325,,,,HOP,-1.338,0.0758425,0.000233044,1.00658 beta-lactamase_625_A282V,beta-lactamase_625_282,TEM-1,beta-lactamase_625,P62593,1.00659,NO,282,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.213352,0.0449821,1.00659 beta-lactamase_625_T126R,beta-lactamase_625_126,TEM-1,beta-lactamase_625,P62593,1.00659,NO,126,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.122,-3.84,2.718,,0.05,H,A,0.22,-0.05,0.817,,44.41,HPH,-1.60467,0.213352,0.00244552,1.00659 PSD95pdz3_D348H,PSD95pdz3_348,PSD95pdz3,PSD95pdz3,P31016,1.00659,NO,348,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.264,-4.137,2.873,5.02473,,,,,16.8925,,,,HAH,-1.306,0.0758425,0.000731866,1.00659 beta-lactamase_156_R118G,beta-lactamase_156_118,TEM-1,beta-lactamase_156,P62593,1.0066,NO,118,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.413,-1.757,-0.656,,0.457,H,A,1.2,1.39,2.231,,77.62,HBA,-1.785,0.111618,0.00538794,1.0066 beta-lactamase_39_D155C,beta-lactamase_39_155,TEM-1,beta-lactamase_39,P62593,1.0066,NO,155,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.889,-5.157,4.268,,0.049,,B,0.75,-0.9,3.208,,64.69,OAB,-1.62267,0.0495842,0.00135315,1.0066 kka2_1:8_L103V,kka2_1:8_103,Kka2,kka2_1:8,P00552,1.0066,NO,103,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-2.362,-2.108,-0.254,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.100394,0.00574792,1.0066 kka2_1:8_L103V,kka2_1:8_103,Kka2,kka2_1:8,P00552,1.0066,NO,103,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-2.362,-2.108,-0.254,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.100394,0.00574792,1.0066 beta-lactamase_156_P250K,beta-lactamase_156_250,TEM-1,beta-lactamase_156,P62593,1.00661,NO,250,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.111618,0.00550899,1.00661 beta-lactamase_625_I206M,beta-lactamase_625_206,TEM-1,beta-lactamase_625,P62593,1.00661,NO,206,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-2.429,-3.069,0.64,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.213352,0.00528934,1.00661 beta-lactamase_625_R118V,beta-lactamase_625_118,TEM-1,beta-lactamase_625,P62593,1.00661,NO,118,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.413,-3.595,1.182,,0.457,H,A,1.2,1.39,2.144,,77.62,HBA,-1.785,0.213352,0.00538794,1.00661 beta-lactamase_R162R,beta-lactamase_162,TEM-1,beta-lactamase,P62593,1.00661,NO,162,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.016,-1.016,,5.34456,0.124,S,B,0.68,-0.37,31.656,31.656,64.69,ABH,-1.25,0.221079,0.000561334,1.00661 beta-lactamase_39_I45Y,beta-lactamase_39_45,TEM-1,beta-lactamase_39,P62593,1.00662,NO,45,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-2.421,-2.914,0.493,,,E,B,0.48,-0.3,2.256,,77.62,HHA,-2.30267,0.0495842,0.00452842,1.00662 beta-lactamase_625_G253M,beta-lactamase_625_253,TEM-1,beta-lactamase_625,P62593,1.00662,NO,253,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.213352,0.00786358,1.00662 beta-lactamase_0_F149T,beta-lactamase_0_149,TEM-1,beta-lactamase_0,P62593,1.00663,NO,149,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.299,-3.669,2.37,,0.195,H,A,0.58,0.11,3.518,,63.99,HHH,-1.46067,0.0500837,0.00418462,1.00663 beta-lactamase_156_A77L,beta-lactamase_156_77,TEM-1,beta-lactamase_156,P62593,1.00663,NO,77,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.234,-2.423,1.189,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.111618,0.00282362,1.00663 beta-lactamase_2500_Q276W,beta-lactamase_2500_276,TEM-1,beta-lactamase_2500,P62593,1.00663,NO,276,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.361275,0.0191712,1.00663 beta-lactamase_39_T138R,beta-lactamase_39_138,TEM-1,beta-lactamase_39,P62593,1.00663,NO,138,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.506,-2.605,0.099,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.0495842,0.00487868,1.00663 beta-lactamase_625_A247M,beta-lactamase_625_247,TEM-1,beta-lactamase_625,P62593,1.00663,NO,247,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.213352,0.00611275,1.00663 beta-lactamase_156_P25I,beta-lactamase_156_25,TEM-1,beta-lactamase_156,P62593,1.00664,NO,25,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.526,-4.029,2.503,,0.624,H,A,0.52,0.14,1.079,,73.08,BOA,-2.15367,0.111618,0.00347571,1.00664 beta-lactamase_2500_R118C,beta-lactamase_2500_118,TEM-1,beta-lactamase_2500,P62593,1.00664,NO,118,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.413,-4.992,2.579,,0.457,H,A,1.2,1.39,2.144,,77.62,HBA,-1.785,0.361275,0.00538794,1.00664 beta-lactamase_39_G194C,beta-lactamase_39_194,TEM-1,beta-lactamase_39,P62593,1.00664,NO,194,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.396,-5.097,3.701,,0.276,S,b,0.29,0.36,4.852,,67.83,POA,-1.832,0.0495842,0.00392163,1.00664 beta-lactamase_0_H110N,beta-lactamase_0_110,TEM-1,beta-lactamase_0,P62593,1.00665,NO,110,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-1.706,-3.626,1.92,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.0500837,0.00441499,1.00665 beta-lactamase_625_E61D,beta-lactamase_625_61,TEM-1,beta-lactamase_625,P62593,1.00665,NO,61,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.115,-1.402,-0.713,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.213352,0.00440955,1.00665 beta-lactamase_625_F149W,beta-lactamase_625_149,TEM-1,beta-lactamase_625,P62593,1.00665,NO,149,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.299,-2.98,1.681,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.213352,0.00418462,1.00665 beta-lactamase_156_A247L,beta-lactamase_156_247,TEM-1,beta-lactamase_156,P62593,1.00666,NO,247,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.48,-2.56,1.08,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.111618,0.00611275,1.00666 beta-lactamase_156_S256G,beta-lactamase_156_256,TEM-1,beta-lactamase_156,P62593,1.00667,NO,256,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.111618,0.00710634,1.00667 beta-lactamase_156_G114T,beta-lactamase_156_114,TEM-1,beta-lactamase_156,P62593,1.00668,NO,114,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.094,-2.276,1.182,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.111618,0.00224919,1.00668 beta-lactamase_156_L167M,beta-lactamase_156_167,TEM-1,beta-lactamase_156,P62593,1.00668,NO,167,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.138,-2.673,1.535,,0.015,G,A,0.55,-0.63,0.4,,64.69,AHP,-1.30767,0.111618,0.00303566,1.00668 beta-lactamase_39_N168I,beta-lactamase_39_168,TEM-1,beta-lactamase_39,P62593,1.00668,NO,168,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-1.029,-3.943,2.914,,0.113,G,A,0.61,-0.4,0.822,,44.41,HPA,-1.13233,0.0495842,0.00288667,1.00668 beta-lactamase_39_T269S,beta-lactamase_39_269,TEM-1,beta-lactamase_39,P62593,1.00668,NO,269,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.156,,,,0.646,H,A,0.53,0.4,3.889,,77.62,HPH,-1.96733,0.0495842,0.00950944,1.00668 beta-lactamase_2500_A182V,beta-lactamase_2500_182,TEM-1,beta-lactamase_2500,P62593,1.00669,NO,182,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.777,-2.556,0.779,,0.136,H,A,0.46,-0.66,2.032,,93.01,OHH,-1.27367,0.361275,0.00559099,1.00669 beta-lactamase_625_R275V,beta-lactamase_625_275,TEM-1,beta-lactamase_625,P62593,1.00669,NO,275,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.213352,0.0141984,1.00669 Pab1_M189L,Pab1_189,Pab1,Pab1,P04147,1.00669,NO,189,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.406,-2.275,0.869,,0.631,E,b,,2.81,,,,OHH,-1.18,0.175299,0.000278756,1.00669 beta-lactamase_156_T193S,beta-lactamase_156_193,TEM-1,beta-lactamase_156,P62593,1.0067,NO,193,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.914,-2.571,0.657,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.111618,0.00482669,1.0067 beta-lactamase_2500_D113T,beta-lactamase_2500_113,TEM-1,beta-lactamase_2500,P62593,1.0067,NO,113,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.829,-2.544,0.715,,0.665,T,A,0.75,0.91,21.104,21.104,73.08,PAO,-1.703,0.361275,0.00474112,1.0067 beta-lactamase_39_A148R,beta-lactamase_39_148,TEM-1,beta-lactamase_39,P62593,1.0067,NO,148,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.757,-2.456,0.699,,0.379,H,A,0.46,-0.55,3.551,,72.73,PHH,-1.40167,0.0495842,0.00547053,1.0067 beta-lactamase_39_K53Y,beta-lactamase_39_53,TEM-1,beta-lactamase_39,P62593,1.0067,NO,53,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-2.313,-4.187,1.874,,0.589,,B,2.34,1.15,15.633,15.633,77.62,OBH,-2.1,0.0495842,0.00383383,1.0067 beta-lactamase_S233T,beta-lactamase_233,TEM-1,beta-lactamase,P62593,1.0067,NO,233,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.886,-1.229,-0.657,4.98121,0.016,E,B,0.48,-1.01,5.361,,77.62,BPO,-1.17267,0.221079,0.00311415,1.0067 PSD95pdz3_G351A,PSD95pdz3_351,PSD95pdz3,PSD95pdz3,P31016,1.0067,NO,351,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.008,-2.534,1.526,5.44798,,,,,20.7625,,,,POA,-1.37133,0.0758425,0.000691282,1.0067 beta-lactamase_0_A246L,beta-lactamase_0_246,TEM-1,beta-lactamase_0,P62593,1.00671,NO,246,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.121,-1.908,-0.213,,0.01,E,B,0.46,-1.01,1.201,,73.78,HHH,-1.55633,0.0500837,0.00569458,1.00671 beta-lactamase_625_H110V,beta-lactamase_625_110,TEM-1,beta-lactamase_625,P62593,1.00671,NO,110,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-1.706,-3.735,2.029,,0.341,G,a,0.17,1.08,31.31,31.31,64.69,BBH,-1.73333,0.213352,0.00441499,1.00671 beta-lactamase_0_G240A,beta-lactamase_0_240,TEM-1,beta-lactamase_0,P62593,1.00672,NO,240,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.0500837,0.00591201,1.00672 beta-lactamase_39_A40V,beta-lactamase_39_40,TEM-1,beta-lactamase_39,P62593,1.00672,NO,40,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.402,-2.649,1.247,,0.155,S,B,0.46,0.21,0.783,,73.78,OHB,-1.40267,0.0495842,0.00490026,1.00672 beta-lactamase_39_G281E,beta-lactamase_39_281,TEM-1,beta-lactamase_39,P62593,1.00672,NO,281,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.0495842,0.0406482,1.00672 kka2_1:2_A166Y,kka2_1:2_166,Kka2,kka2_1:2,P00552,1.00672,NO,166,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.407,-4.444,2.037,,0.534,.,B,0.46,1.03,23.175,23.175,71.59,HHO,-2.421,0.295029,0.00799912,1.00672 beta-lactamase_625_N50R,beta-lactamase_625_50,TEM-1,beta-lactamase_625,P62593,1.00673,NO,50,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-2.979,-3.883,0.904,,0.912,T,A,0.61,1.24,3.446,,77.62,HPP,-2.134,0.213352,0.0047211,1.00673 beta-lactamase_S254H,beta-lactamase_254,TEM-1,beta-lactamase,P62593,1.00673,NO,254,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.126,-4.653,2.527,5.49575,0.312,,a,0.25,-0.48,24.91,24.91,69.58,OPB,-2.215,0.221079,0.00369,1.00673 beta-lactamase_39_L196I,beta-lactamase_39_196,TEM-1,beta-lactamase_39,P62593,1.00674,NO,196,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-2.478,-2.648,0.17,,0.518,S,A,0.55,1.35,12.152,12.152,77.62,AHH,-1.839,0.0495842,0.00512144,1.00674 beta-lactamase_39_L248A,beta-lactamase_39_248,TEM-1,beta-lactamase_39,P62593,1.00674,NO,248,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.0495842,0.00428493,1.00674 beta-lactamase_39_T269H,beta-lactamase_39_269,TEM-1,beta-lactamase_39,P62593,1.00674,NO,269,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.156,,,,0.646,H,A,0.53,0.4,3.889,,77.62,HPH,-1.96733,0.0495842,0.00950944,1.00674 beta-lactamase_156_W208M,beta-lactamase_156_208,TEM-1,beta-lactamase_156,P62593,1.00675,NO,208,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-0.818,-4.48,3.662,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.111618,0.00126609,1.00675 beta-lactamase_39_E46F,beta-lactamase_39_46,TEM-1,beta-lactamase_39,P62593,1.00675,NO,46,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.94,-4.056,2.116,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.0495842,0.00427568,1.00675 beta-lactamase_625_Q37K,beta-lactamase_625_37,TEM-1,beta-lactamase_625,P62593,1.00675,NO,37,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.134,-2.595,0.461,,0.613,H,A,0.64,1.98,1.318,,73.08,APH,-2.06967,0.213352,0.00425833,1.00675 beta-lactamase_I93V,beta-lactamase_93,TEM-1,beta-lactamase,P62593,1.00675,NO,93,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.401,-1.692,0.291,5.74695,0.128,E,B,0.77,0.44,1.757,,67.83,BHB,-1.873,0.221079,0.00527066,1.00675 beta-lactamase_0_K286D,beta-lactamase_0_286,TEM-1,beta-lactamase_0,P62593,1.00676,NO,286,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.0500837,,1.00676 beta-lactamase_39_Q97V,beta-lactamase_39_97,TEM-1,beta-lactamase_39,P62593,1.00676,NO,97,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.072,-3.633,1.561,,0.823,G,A,0.64,2.42,4.457,,77.62,PPP,-2.43833,0.0495842,0.0045116,1.00676 beta-lactamase_625_N274E,beta-lactamase_625_274,TEM-1,beta-lactamase_625,P62593,1.00676,NO,274,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.213352,0.0110418,1.00676 beta-lactamase_T186D,beta-lactamase_186,TEM-1,beta-lactamase,P62593,1.00676,NO,186,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.522,-2.935,0.413,5.07364,0.396,H,A,0.3,-0.28,2.144,,77.62,HPP,-1.77633,0.221079,0.00485034,1.00676 kka2_1:8_H139K,kka2_1:8_139,Kka2,kka2_1:8,P00552,1.00676,NO,139,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-2.809,-2.699,-0.11,,0.471,H,A,0.17,0.68,28.583,28.583,63.64,BBB,-2.22,0.100394,0.00734779,1.00676 kka2_1:8_H139K,kka2_1:8_139,Kka2,kka2_1:8,P00552,1.00676,NO,139,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-2.809,-2.699,-0.11,,0.471,H,A,0.17,0.68,28.583,28.583,63.64,BBB,-2.22,0.100394,0.00734779,1.00676 beta-lactamase_2500_V117I,beta-lactamase_2500_117,TEM-1,beta-lactamase_2500,P62593,1.00677,NO,117,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.53,-1.923,0.393,,,H,A,0.44,-0.34,1.23,,65.03,PHB,-1.741,0.361275,0.00467906,1.00677 beta-lactamase_39_R242Y,beta-lactamase_39_242,TEM-1,beta-lactamase_39,P62593,1.00678,NO,242,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.0495842,0.00452879,1.00678 beta-lactamase_625_L150T,beta-lactamase_625_150,TEM-1,beta-lactamase_625,P62593,1.00678,NO,150,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.326,-2.5,1.174,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.213352,0.00463171,1.00678 beta-lactamase_625_P255R,beta-lactamase_625_255,TEM-1,beta-lactamase_625,P62593,1.00678,NO,255,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-2.266,-4.188,1.922,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.213352,0.00499612,1.00678 beta-lactamase_A84G,beta-lactamase_84,TEM-1,beta-lactamase,P62593,1.00678,NO,84,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.651,-3.358,1.707,5.28927,0.65,T,A,0.52,0.96,1.863,,68.18,AHO,-1.24267,0.221079,0.00503822,1.00678 beta-lactamase_2500_L196V,beta-lactamase_2500_196,TEM-1,beta-lactamase_2500,P62593,1.00679,NO,196,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-2.478,-2.258,-0.22,,0.518,S,A,0.55,1.35,7.897,,77.62,AHH,-1.839,0.361275,0.00512144,1.00679 beta-lactamase_39_Q86T,beta-lactamase_39_86,TEM-1,beta-lactamase_39,P62593,1.00679,NO,86,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.4,-2.587,0.187,,0.696,S,A,0.64,2.38,27.704,27.704,77.62,OPA,-1.61067,0.0495842,0.00450027,1.00679 beta-lactamase_625_M184V,beta-lactamase_625_184,TEM-1,beta-lactamase_625,P62593,1.00679,NO,184,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.593,-2.346,0.753,,,H,A,0.55,-0.87,2.765,,62.94,HHH,-1.41,0.213352,0.00356019,1.00679 beta-lactamase_2500_E238F,beta-lactamase_2500_238,TEM-1,beta-lactamase_2500,P62593,1.0068,NO,238,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.361275,0.00743256,1.0068 beta-lactamase_39_L219E,beta-lactamase_39_219,TEM-1,beta-lactamase_39,P62593,1.0068,NO,219,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.313,-3.999,2.686,,,I,A,0.55,-0.51,19.842,19.842,74.48,HHB,-1.21533,0.0495842,0.00664345,1.0068 beta-lactamase_39_L79F,beta-lactamase_39_79,TEM-1,beta-lactamase_39,P62593,1.00681,NO,79,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.842,-3.643,2.801,,0.007,H,A,0.55,-0.16,0.823,,50.35,HHP,-1.44333,0.0495842,0.000947397,1.00681 beta-lactamase_39_R59M,beta-lactamase_39_59,TEM-1,beta-lactamase_39,P62593,1.00681,NO,59,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.345,-4.605,3.26,,0.329,S,L,1.2,-0.09,1.806,,73.08,HBO,-2.24267,0.0495842,0.00318082,1.00681 beta-lactamase_625_N274A,beta-lactamase_625_274,TEM-1,beta-lactamase_625,P62593,1.00681,NO,274,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.213352,0.0110418,1.00681 beta-lactamase_156_H24N,beta-lactamase_156_24,TEM-1,beta-lactamase_156,P62593,1.00682,NO,24,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-2.481,-3.496,1.015,,,,,,,2.708,,93.01,OBO,-2.0035,0.111618,0.00238894,1.00682 beta-lactamase_156_L49H,beta-lactamase_156_49,TEM-1,beta-lactamase_156,P62593,1.00682,NO,49,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.897,-4.794,2.897,,0.131,T,A,0.55,0.04,3.112,,64.69,AHP,-1.99233,0.111618,0.00401477,1.00682 beta-lactamase_39_A215V,beta-lactamase_39_215,TEM-1,beta-lactamase_39,P62593,1.00682,NO,215,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.503,-3.464,1.961,,,,a,0.46,-0.93,0.494,,74.48,HHO,-1.42633,0.0495842,0.00544007,1.00682 beta-lactamase_2500_H151R,beta-lactamase_2500_151,TEM-1,beta-lactamase_2500,P62593,1.00683,NO,151,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-2.96,-1.217,-1.743,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.361275,0.00216946,1.00683 beta-lactamase_2500_Q88T,beta-lactamase_2500_88,TEM-1,beta-lactamase_2500,P62593,1.00683,NO,88,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.086,-2.693,0.607,,0.807,,B,0.64,2.03,1.84,,77.62,APH,-1.53433,0.361275,0.00504167,1.00683 beta-lactamase_39_S241L,beta-lactamase_39_241,TEM-1,beta-lactamase_39,P62593,1.00683,NO,241,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.0495842,0.00452736,1.00683 beta-lactamase_625_G39L,beta-lactamase_625_39,TEM-1,beta-lactamase_625,P62593,1.00683,NO,39,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.864,-3.751,1.887,,0.701,T,L,0.29,0.47,29.926,29.926,77.62,HOH,-1.53633,0.213352,0.00487611,1.00683 beta-lactamase_625_H24C,beta-lactamase_625_24,TEM-1,beta-lactamase_625,P62593,1.00683,NO,24,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-2.481,-4.897,2.416,,,,,,,2.708,,93.01,OBO,-2.0035,0.213352,0.00238894,1.00683 beta-lactamase_39_A133P,beta-lactamase_39_133,TEM-1,beta-lactamase_39,P62593,1.00684,NO,133,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.186,-3.811,2.625,,,H,A,0.46,-0.86,0.373,,67.83,HHP,-0.988333,0.0495842,0.00468022,1.00684 beta-lactamase_39_T193H,beta-lactamase_39_193,TEM-1,beta-lactamase_39,P62593,1.00684,NO,193,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.914,-4.78,2.866,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.0495842,0.00482669,1.00684 beta-lactamase_625_R275F,beta-lactamase_625_275,TEM-1,beta-lactamase_625,P62593,1.00684,NO,275,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.213352,0.0141984,1.00684 beta-lactamase_625_S221P,beta-lactamase_625_221,TEM-1,beta-lactamase_625,P62593,1.00684,NO,221,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.754,-3.814,2.06,,0.624,H,A,0.27,-0.2,1.495,,74.48,BPH,-1.59967,0.213352,0.0046094,1.00684 kka2_1:8_A229E,kka2_1:8_229,Kka2,kka2_1:8,P00552,1.00684,NO,229,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.739,-2.079,0.34,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.100394,0.00942138,1.00684 kka2_1:8_A229E,kka2_1:8_229,Kka2,kka2_1:8,P00552,1.00684,NO,229,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.739,-2.079,0.34,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.100394,0.00942138,1.00684 beta-lactamase_156_L146I,beta-lactamase_156_146,TEM-1,beta-lactamase_156,P62593,1.00685,NO,146,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.462,-2.631,1.169,,0.007,H,A,0.55,-0.56,1.578,,64.69,AHP,-1.656,0.111618,0.00474542,1.00685 beta-lactamase_156_A124V,beta-lactamase_156_124,TEM-1,beta-lactamase_156,P62593,1.00686,NO,124,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.181,-2.519,1.338,,,H,A,0.46,-0.9,2.027,,64.34,HHH,-1.152,0.111618,0.00481399,1.00686 beta-lactamase_156_A225H,beta-lactamase_156_225,TEM-1,beta-lactamase_156,P62593,1.00686,NO,225,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.845,-3.109,1.264,,1,T,B,0.46,-0.38,11.722,11.722,74.48,OHO,-1.39967,0.111618,0.00465057,1.00686 beta-lactamase_39_K53G,beta-lactamase_39_53,TEM-1,beta-lactamase_39,P62593,1.00686,NO,53,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-2.313,-2.824,0.511,,0.589,,B,2.34,1.15,15.633,15.633,77.62,OBH,-2.1,0.0495842,0.00383383,1.00686 beta-lactamase_39_R41L,beta-lactamase_39_41,TEM-1,beta-lactamase_39,P62593,1.00686,NO,41,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-0.942,-3.384,2.442,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.0495842,0.00123327,1.00686 beta-lactamase_0_P172D,beta-lactamase_0_172,TEM-1,beta-lactamase_0,P62593,1.00687,NO,172,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.998,-3.578,2.58,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.0500837,0.00312594,1.00687 beta-lactamase_156_G194L,beta-lactamase_156_194,TEM-1,beta-lactamase_156,P62593,1.00687,NO,194,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.396,-3.731,2.335,,0.276,S,b,0.29,0.36,1.346,,67.83,POA,-1.832,0.111618,0.00392163,1.00687 beta-lactamase_156_L188Y,beta-lactamase_156_188,TEM-1,beta-lactamase_156,P62593,1.00687,NO,188,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.166,-3.998,2.832,,,H,A,0.55,-0.3,1.574,,60.14,PHB,-1.47033,0.111618,0.00295687,1.00687 beta-lactamase_39_H24M,beta-lactamase_39_24,TEM-1,beta-lactamase_39,P62593,1.00687,NO,24,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-2.481,-3.144,0.663,,,,,,,2.708,,93.01,OBO,-2.0035,0.0495842,0.00238894,1.00687 beta-lactamase_39_I244Q,beta-lactamase_39_244,TEM-1,beta-lactamase_39,P62593,1.00687,NO,244,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.555,-4.255,2.7,,,E,B,0.48,-0.84,1.325,,77.62,OHH,-1.385,0.0495842,0.00605379,1.00687 beta-lactamase_39_N168R,beta-lactamase_39_168,TEM-1,beta-lactamase_39,P62593,1.00687,NO,168,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-1.029,-3.58,2.551,,0.113,G,A,0.61,-0.4,0.822,,44.41,HPA,-1.13233,0.0495842,0.00288667,1.00687 beta-lactamase_39_P217E,beta-lactamase_39_217,TEM-1,beta-lactamase_39,P62593,1.00687,NO,217,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-2.062,-2.651,0.589,,0.496,I,A,0.52,-0.33,21.172,21.172,74.48,OOH,-1.64333,0.0495842,0.00463211,1.00687 PSD95pdz3_P346Q,PSD95pdz3_346,PSD95pdz3,PSD95pdz3,P31016,1.00687,NO,346,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.236,-3.581,2.345,5.02406,,,,,14.6629,,,,OOH,-1.18367,0.0758425,0.000758563,1.00687 beta-lactamase_156_K190S,beta-lactamase_156_190,TEM-1,beta-lactamase_156,P62593,1.00688,NO,190,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.994,-2.653,0.659,,0.371,H,A,2.34,0.16,1.513,,77.62,BBH,-1.64167,0.111618,0.00574527,1.00688 kka2_1:1_G55L,kka2_1:1_55,Kka2,kka2_1:1,P00552,1.00688,NO,55,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.625,-2.999,1.374,,0.517,S,b,0.29,1.19,4.035,,63.64,POH,-2.05967,0.520039,0.00667877,1.00688 beta-lactamase_156_E56Y,beta-lactamase_156_56,TEM-1,beta-lactamase_156,P62593,1.00689,NO,56,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.043,-4.216,2.173,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.111618,0.00238534,1.00689 beta-lactamase_625_L89I,beta-lactamase_625_89,TEM-1,beta-lactamase_625,P62593,1.00689,NO,89,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.096,-3.166,2.07,,0.168,T,A,0.55,0.63,1.599,,64.34,PHO,-1.75767,0.213352,0.00207068,1.00689 beta-lactamase_E145H,beta-lactamase_145,TEM-1,beta-lactamase,P62593,1.00689,NO,145,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.357,-4.656,2.299,5.38104,0.545,H,A,0.52,0.79,2.124,,77.62,BAH,-2.069,0.221079,0.00553285,1.00689 beta-lactamase_G39N,beta-lactamase_39,TEM-1,beta-lactamase,P62593,1.00689,NO,39,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.864,-2.55,0.686,5.35574,0.701,T,L,0.23,0.47,29.926,29.926,77.62,HOH,-1.53633,0.221079,0.00487611,1.00689 beta-lactamase_Q204N,beta-lactamase_204,TEM-1,beta-lactamase,P62593,1.00689,NO,204,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-1.382,-3.623,2.241,5.46394,0.204,H,A,0.12,0.09,1.707,,66.08,PPH,-1.49067,0.221079,0.00364106,1.00689 beta-lactamase_S254M,beta-lactamase_254,TEM-1,beta-lactamase,P62593,1.00689,NO,254,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.126,-4.767,2.641,5.49575,0.312,,a,0.25,-0.48,24.91,24.91,69.58,OPB,-2.215,0.221079,0.00369,1.00689 beta-lactamase_V8I,beta-lactamase_8,TEM-1,beta-lactamase,P62593,1.00689,NO,8,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-2.358,-3.145,0.787,,,,,,,0.575,,77.62,BHH,-2.06267,0.221079,0.00226401,1.00689 kka2_1:8_A41E,kka2_1:8_41,Kka2,kka2_1:8,P00552,1.00689,NO,41,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.879,-3.093,1.214,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.100394,0.00543332,1.00689 kka2_1:8_A41E,kka2_1:8_41,Kka2,kka2_1:8,P00552,1.00689,NO,41,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.879,-3.093,1.214,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.100394,0.00543332,1.00689 Pab1_V198L,Pab1_198,Pab1,Pab1,P04147,1.00689,NO,198,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.113,-2.5,1.387,,0.008,E,B,0.61,0.91,,,,HHH,-1.32933,0.175299,0.000268557,1.00689 beta-lactamase_156_S122H,beta-lactamase_156_122,TEM-1,beta-lactamase_156,P62593,1.0069,NO,122,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.406,-2.676,0.27,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.111618,0.00497825,1.0069 beta-lactamase_625_E108F,beta-lactamase_625_108,TEM-1,beta-lactamase_625,P62593,1.0069,NO,108,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.46,-4.416,2.956,,0.572,G,A,1.04,1.87,20.151,20.151,72.73,PAB,-1.437,0.213352,0.00413372,1.0069 beta-lactamase_0_D174Q,beta-lactamase_0_174,TEM-1,beta-lactamase_0,P62593,1.00691,NO,174,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.738,-3.674,2.936,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.0500837,0.00125633,1.00691 beta-lactamase_156_S104A,beta-lactamase_156_104,TEM-1,beta-lactamase_156,P62593,1.00691,NO,104,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.015,-2.043,1.028,,0.04,,b,0.27,0.57,4.02,,63.29,HPO,-1.05267,0.111618,0.00218083,1.00691 beta-lactamase_156_V72L,beta-lactamase_156_72,TEM-1,beta-lactamase_156,P62593,1.00691,NO,72,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.658,-2.403,0.745,,,H,A,0.44,-1.03,1.92,,65.73,BHH,-1.32167,0.111618,0.00501194,1.00691 beta-lactamase_625_A200G,beta-lactamase_625_200,TEM-1,beta-lactamase_625,P62593,1.00691,NO,200,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.878,-2.76,0.882,,0.757,H,A,0.46,-0.19,12.672,12.672,77.62,HHP,-2.001,0.213352,0.0060056,1.00691 beta-lactamase_625_L167C,beta-lactamase_625_167,TEM-1,beta-lactamase_625,P62593,1.00691,NO,167,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.138,-4.763,3.625,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.213352,0.00303566,1.00691 beta-lactamase_0_P172E,beta-lactamase_0_172,TEM-1,beta-lactamase_0,P62593,1.00692,NO,172,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.998,-3.52,2.522,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.0500837,0.00312594,1.00692 beta-lactamase_625_N173S,beta-lactamase_625_173,TEM-1,beta-lactamase_625,P62593,1.00692,NO,173,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-2.663,-3.203,0.54,,1.044,T,l,0.61,1.25,1.426,,77.62,OPA,-1.46633,0.213352,0.0033769,1.00692 beta-lactamase_A225G,beta-lactamase_225,TEM-1,beta-lactamase,P62593,1.00692,NO,225,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.845,-2.827,0.982,6.5181,1,T,B,0.58,-0.38,4.077,,74.48,OHO,-1.39967,0.221079,0.00465057,1.00692 kka2_1:1_G234Q,kka2_1:1_234,Kka2,kka2_1:1,P00552,1.00692,NO,234,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-2.9,-2.619,-0.281,,0.494,H,A,0.29,-0.29,1.753,,71.59,OOA,-1.86767,0.520039,0.00984449,1.00692 kka2_1:8_E142H,kka2_1:8_142,Kka2,kka2_1:8,P00552,1.00692,NO,142,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.221,-3.221,1,,0.471,H,A,1.04,0.85,2.655,,65.53,HAB,-2.08033,0.100394,0.00748883,1.00692 kka2_1:8_E142H,kka2_1:8_142,Kka2,kka2_1:8,P00552,1.00692,NO,142,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.221,-3.221,1,,0.471,H,A,1.04,0.85,2.655,,65.53,HAB,-2.08033,0.100394,0.00748883,1.00692 beta-lactamase_39_K190S,beta-lactamase_39_190,TEM-1,beta-lactamase_39,P62593,1.00693,NO,190,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.994,-2.653,0.659,,0.371,H,A,2.34,0.16,1.513,,77.62,BBH,-1.64167,0.0495842,0.00574527,1.00693 beta-lactamase_2500_L223V,beta-lactamase_2500_223,TEM-1,beta-lactamase_2500,P62593,1.00694,NO,223,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.055,-2.195,1.14,,0.27,,B,0.55,0.09,1.334,,74.48,HHO,-1.35033,0.361275,0.00372793,1.00694 beta-lactamase_39_E238S,beta-lactamase_39_238,TEM-1,beta-lactamase_39,P62593,1.00694,NO,238,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.0495842,0.00743256,1.00694 beta-lactamase_39_F64L,beta-lactamase_39_64,TEM-1,beta-lactamase_39,P62593,1.00694,NO,64,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-0.841,-2.908,2.067,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.0495842,0.000947691,1.00694 beta-lactamase_39_L89S,beta-lactamase_39_89,TEM-1,beta-lactamase_39,P62593,1.00694,NO,89,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.096,-3.54,2.444,,0.168,T,A,0.55,0.63,3.233,,64.34,PHO,-1.75767,0.0495842,0.00207068,1.00694 beta-lactamase_625_T131C,beta-lactamase_625_131,TEM-1,beta-lactamase_625,P62593,1.00694,NO,131,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.328,-3.123,1.795,,,H,A,0.22,-0.69,2.031,,67.48,PPH,-1.00867,0.213352,0.00345886,1.00694 beta-lactamase_156_A200T,beta-lactamase_156_200,TEM-1,beta-lactamase_156,P62593,1.00695,NO,200,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.878,-2.493,0.615,,0.757,H,A,0.46,-0.19,16.368,16.368,77.62,HHP,-2.001,0.111618,0.0060056,1.00695 beta-lactamase_156_M209A,beta-lactamase_156_209,TEM-1,beta-lactamase_156,P62593,1.00695,NO,209,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.442,-3.177,1.735,,,H,A,0.55,-0.97,1.066,,64.69,HHA,-1.52633,0.111618,0.00625021,1.00695 beta-lactamase_39_A183E,beta-lactamase_39_183,TEM-1,beta-lactamase_39,P62593,1.00695,NO,183,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.231,-3.42,2.189,,0.155,H,A,0.46,-0.91,1.237,,77.62,HHH,-1.53367,0.0495842,0.00296631,1.00695 beta-lactamase_A225V,beta-lactamase_225,TEM-1,beta-lactamase,P62593,1.00695,NO,225,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.845,-3.655,1.81,6.5181,1,T,B,0.58,-0.38,4.077,,74.48,OHO,-1.39967,0.221079,0.00465057,1.00695 kka2_1:8_D52T,kka2_1:8_52,Kka2,kka2_1:8,P00552,1.00695,NO,52,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.271,-3.473,1.202,,0.22,E,B,0.75,0.8,5.447,,71.59,PAH,-2.38367,0.100394,0.00175694,1.00695 kka2_1:8_D52T,kka2_1:8_52,Kka2,kka2_1:8,P00552,1.00695,NO,52,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.271,-3.473,1.202,,0.22,E,B,0.75,0.8,5.447,,71.59,PAH,-2.38367,0.100394,0.00175694,1.00695 beta-lactamase_156_P181T,beta-lactamase_156_181,TEM-1,beta-lactamase_156,P62593,1.00696,NO,181,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.813,-3.419,2.606,,,H,A,0.52,-1.14,1.078,,61.54,HOH,-1.795,0.111618,0.000703122,1.00696 Pab1_G169A,Pab1_169,Pab1,Pab1,P04147,1.00696,NO,169,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.809,-2.67,1.861,,,E,b,0.35,0.03,,,,HOH,-1.11567,0.175299,0.000302434,1.00696 beta-lactamase_2500_R189M,beta-lactamase_2500_189,TEM-1,beta-lactamase_2500,P62593,1.00697,NO,189,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.844,-4.718,2.874,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.361275,0.0050699,1.00697 beta-lactamase_39_V259C,beta-lactamase_39_259,TEM-1,beta-lactamase_39,P62593,1.00698,NO,259,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.0495842,0.0070773,1.00698 beta-lactamase_625_G226N,beta-lactamase_625_226,TEM-1,beta-lactamase_625,P62593,1.00698,NO,226,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.461,-2.628,1.167,,0.701,T,l,0.29,-0.25,3.199,,74.48,HOH,-1.42933,0.213352,0.00665294,1.00698 beta-lactamase_625_I258M,beta-lactamase_625_258,TEM-1,beta-lactamase_625,P62593,1.00698,NO,258,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.213352,0.007931,1.00698 beta-lactamase_39_G249N,beta-lactamase_39_249,TEM-1,beta-lactamase_39,P62593,1.00699,NO,249,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.312,,,,0.256,S,B,0.23,0.04,30.841,30.841,72.73,HOO,-1.81367,0.0495842,0.00220169,1.00699 beta-lactamase_39_M270P,beta-lactamase_39_270,TEM-1,beta-lactamase_39,P62593,1.00699,NO,270,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.0495842,0.00767762,1.00699 beta-lactamase_39_N152I,beta-lactamase_39_152,TEM-1,beta-lactamase_39,P62593,1.00699,NO,152,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-2.757,-3.192,0.435,,0.863,H,A,0.61,0.92,4.038,,77.62,BPH,-2.97,0.0495842,0.00471429,1.00699 beta-lactamase_39_V157C,beta-lactamase_39_157,TEM-1,beta-lactamase_39,P62593,1.00699,NO,157,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.751,-4.91,3.159,,0.308,S,a,0.44,-0.75,10.364,10.364,69.58,BHP,-2.00767,0.0495842,0.00506849,1.00699 beta-lactamase_625_E238T,beta-lactamase_625_238,TEM-1,beta-lactamase_625,P62593,1.00699,NO,238,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.213352,0.00743256,1.00699 kka2_1:8_M120I,kka2_1:8_120,Kka2,kka2_1:8,P00552,1.00699,NO,120,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-3.877,-2.912,-0.965,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.100394,0.00265808,1.00699 kka2_1:8_M120I,kka2_1:8_120,Kka2,kka2_1:8,P00552,1.00699,NO,120,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-3.877,-2.912,-0.965,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.100394,0.00265808,1.00699 beta-lactamase_156_R41S,beta-lactamase_156_41,TEM-1,beta-lactamase_156,P62593,1.007,NO,41,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-0.942,-2.526,1.584,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.111618,0.00123327,1.007 beta-lactamase_2500_Q88S,beta-lactamase_2500_88,TEM-1,beta-lactamase_2500,P62593,1.00701,NO,88,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.086,-2.48,0.394,,0.807,,B,0.64,2.03,1.84,,77.62,APH,-1.53433,0.361275,0.00504167,1.00701 kka2_1:8_E182Y,kka2_1:8_182,Kka2,kka2_1:8,P00552,1.00701,NO,182,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.516,-3.156,1.64,,0.326,,B,1.52,0.75,2.568,,65.53,OAA,-1.806,0.100394,0.00641548,1.00701 kka2_1:8_E182Y,kka2_1:8_182,Kka2,kka2_1:8,P00552,1.00701,NO,182,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.516,-3.156,1.64,,0.326,,B,1.52,0.75,2.568,,65.53,OAA,-1.806,0.100394,0.00641548,1.00701 beta-lactamase_156_D36A,beta-lactamase_156_36,TEM-1,beta-lactamase_156,P62593,1.00702,NO,36,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.732,-2.434,-0.298,,0.555,H,A,0.75,1.17,14.871,14.871,77.62,AAP,-1.91167,0.111618,0.00476483,1.00702 beta-lactamase_2500_N173Q,beta-lactamase_2500_173,TEM-1,beta-lactamase_2500,P62593,1.00702,NO,173,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-2.663,-4.003,1.34,,1.044,T,l,0.61,1.25,1.88,,77.62,OPA,-1.46633,0.361275,0.0033769,1.00702 beta-lactamase_39_Q267C,beta-lactamase_39_267,TEM-1,beta-lactamase_39,P62593,1.00702,NO,267,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.0495842,0.0102128,1.00702 beta-lactamase_625_Q204F,beta-lactamase_625_204,TEM-1,beta-lactamase_625,P62593,1.00702,NO,204,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-1.382,-4.303,2.921,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.213352,0.00364106,1.00702 beta-lactamase_A15I,beta-lactamase_15,TEM-1,beta-lactamase,P62593,1.00702,NO,15,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.654,-3.464,1.81,,,,,,,31.998,31.998,93.01,HHH,-2.10833,0.221079,0.00248966,1.00702 beta-lactamase_S281I,beta-lactamase_281,TEM-1,beta-lactamase,P62593,1.00702,NO,281,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.247,-2.752,0.505,4.73591,0.128,H,A,0.25,-0.26,2.144,,77.62,HPH,-1.847,0.221079,0.0406482,1.00702 beta-lactamase_156_A183T,beta-lactamase_156_183,TEM-1,beta-lactamase_156,P62593,1.00703,NO,183,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.231,-3.281,2.05,,0.155,H,A,0.46,-0.91,23.859,23.859,77.62,HHH,-1.53367,0.111618,0.00296631,1.00703 beta-lactamase_39_M270T,beta-lactamase_39_270,TEM-1,beta-lactamase_39,P62593,1.00703,NO,270,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.0495842,0.00767762,1.00703 beta-lactamase_39_S122P,beta-lactamase_39_122,TEM-1,beta-lactamase_39,P62593,1.00703,NO,122,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.406,-4.011,1.605,,0.352,H,A,0.27,-0.54,2.004,,77.62,OPH,-1.39767,0.0495842,0.00497825,1.00703 beta-lactamase_625_V157Y,beta-lactamase_625_157,TEM-1,beta-lactamase_625,P62593,1.00703,NO,157,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.751,-2.838,1.087,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.213352,0.00506849,1.00703 beta-lactamase_2500_M180T,beta-lactamase_2500_180,TEM-1,beta-lactamase_2500,P62593,1.00704,NO,180,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-2.795,-1.278,-1.517,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.361275,0.00552048,1.00704 beta-lactamase_156_V214M,beta-lactamase_156_214,TEM-1,beta-lactamase_156,P62593,1.00705,NO,214,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.299,-4.251,2.952,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.111618,0.00628442,1.00705 beta-lactamase_625_E145C,beta-lactamase_625_145,TEM-1,beta-lactamase_625,P62593,1.00705,NO,145,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.357,-5.044,2.687,,0.545,H,A,1.04,0.79,2.64,,77.62,BAH,-2.069,0.213352,0.00553285,1.00705 beta-lactamase_625_L28C,beta-lactamase_625_28,TEM-1,beta-lactamase_625,P62593,1.00705,NO,28,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.579,-4.763,3.184,,0.277,H,A,0.55,-0.16,2.716,,93.01,PHH,-2.11333,0.213352,0.00359321,1.00705 beta-lactamase_0_F149E,beta-lactamase_0_149,TEM-1,beta-lactamase_0,P62593,1.00706,NO,149,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.299,-3.842,2.543,,0.195,H,A,0.58,0.11,3.518,,63.99,HHH,-1.46067,0.0500837,0.00418462,1.00706 beta-lactamase_39_P181T,beta-lactamase_39_181,TEM-1,beta-lactamase_39,P62593,1.00706,NO,181,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.813,-3.419,2.606,,,H,A,0.52,-1.14,1.946,,61.54,HOH,-1.795,0.0495842,0.000703122,1.00706 beta-lactamase_625_A182L,beta-lactamase_625_182,TEM-1,beta-lactamase_625,P62593,1.00706,NO,182,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.777,-3.486,1.709,,0.136,H,A,0.46,-0.66,16.784,16.784,93.01,OHH,-1.27367,0.213352,0.00559099,1.00706 beta-lactamase_625_G281T,beta-lactamase_625_281,TEM-1,beta-lactamase_625,P62593,1.00706,NO,281,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.213352,0.0406482,1.00706 beta-lactamase_156_D212K,beta-lactamase_156_212,TEM-1,beta-lactamase_156,P62593,1.00707,NO,212,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.624,-3.581,1.957,,0.037,,b,0.75,-0.58,20.222,20.222,74.48,HAB,-1.77667,0.111618,0.00644302,1.00707 beta-lactamase_39_E108N,beta-lactamase_39_108,TEM-1,beta-lactamase_39,P62593,1.00707,NO,108,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.46,-3.593,2.133,,0.572,G,A,1.04,1.87,20.151,20.151,72.73,PAB,-1.437,0.0495842,0.00413372,1.00707 beta-lactamase_156_P181C,beta-lactamase_156_181,TEM-1,beta-lactamase_156,P62593,1.00708,NO,181,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.813,-5.009,4.196,,,H,A,0.52,-1.14,1.078,,61.54,HOH,-1.795,0.111618,0.000703122,1.00708 beta-lactamase_156_P224H,beta-lactamase_156_224,TEM-1,beta-lactamase_156,P62593,1.00708,NO,224,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.893,-4.649,3.756,,0.383,,B,0.52,-0.3,0.383,,74.48,HOH,-1.26433,0.111618,0.00189564,1.00708 beta-lactamase_2500_A182L,beta-lactamase_2500_182,TEM-1,beta-lactamase_2500,P62593,1.00708,NO,182,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.777,-3.486,1.709,,0.136,H,A,0.46,-0.66,2.032,,93.01,OHH,-1.27367,0.361275,0.00559099,1.00708 beta-lactamase_625_V106W,beta-lactamase_625_106,TEM-1,beta-lactamase_625,P62593,1.00708,NO,106,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.218,-5.22,4.002,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.213352,0.00304168,1.00708 beta-lactamase_625_Y44M,beta-lactamase_625_44,TEM-1,beta-lactamase_625,P62593,1.00709,NO,44,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-2.547,-2.521,-0.026,,,E,B,0.21,-0.45,2.371,,73.78,OHH,-1.86267,0.213352,0.00426364,1.00709 beta-lactamase_39_R162G,beta-lactamase_39_162,TEM-1,beta-lactamase_39,P62593,1.0071,NO,162,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.016,-3.445,2.429,,0.124,S,B,1.2,-0.37,31.656,31.656,64.69,ABH,-1.25,0.0495842,0.000561334,1.0071 kka2_1:2_W91G,kka2_1:2_91,Kka2,kka2_1:2,P00552,1.00711,NO,91,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-1.178,-3.516,2.338,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.295029,0.00358653,1.00711 beta-lactamase_2500_A182W,beta-lactamase_2500_182,TEM-1,beta-lactamase_2500,P62593,1.00712,NO,182,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.777,-5.53,3.753,,0.136,H,A,0.46,-0.66,2.032,,93.01,OHH,-1.27367,0.361275,0.00559099,1.00712 beta-lactamase_39_G141T,beta-lactamase_39_141,TEM-1,beta-lactamase_39,P62593,1.00712,NO,141,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.828,-3.647,2.819,,0.575,T,l,0.29,-0.28,0.722,,64.69,HOO,-1.08933,0.0495842,0.0012419,1.00712 beta-lactamase_156_I54N,beta-lactamase_156_54,TEM-1,beta-lactamase_156,P62593,1.00713,NO,54,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-2.838,-2.849,0.011,,0.669,E,B,0.48,-0.14,0.541,,73.78,BHH,-2.337,0.111618,0.00403589,1.00713 beta-lactamase_2500_H287N,beta-lactamase_2500_287,TEM-1,beta-lactamase_2500,P62593,1.00713,NO,287,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,,,,,,,,,,,,,BBH,-1.111,0.361275,,1.00713 beta-lactamase_39_G265F,beta-lactamase_39_265,TEM-1,beta-lactamase_39,P62593,1.00713,NO,265,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.0495842,0.00811926,1.00713 beta-lactamase_39_Y44I,beta-lactamase_39_44,TEM-1,beta-lactamase_39,P62593,1.00713,NO,44,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-2.547,-2.364,-0.183,,,E,B,0.21,-0.45,2.683,,73.78,OHH,-1.86267,0.0495842,0.00426364,1.00713 beta-lactamase_H94F,beta-lactamase_94,TEM-1,beta-lactamase,P62593,1.00713,NO,94,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-2.5,-4.323,1.823,6.1507,0.776,,B,0.63,1.24,1.176,,77.62,HBH,-1.872,0.221079,0.00389226,1.00713 beta-lactamase_L196W,beta-lactamase_196,TEM-1,beta-lactamase,P62593,1.00713,NO,196,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-2.478,-5.492,3.014,,0.518,S,A,0.55,1.35,,,77.62,AHH,-1.839,0.221079,0.00512144,1.00713 beta-lactamase_S80H,beta-lactamase_80,TEM-1,beta-lactamase,P62593,1.00713,NO,80,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.029,-3.359,1.33,5.23748,0.192,H,A,0.25,0.46,2.256,,77.62,HPB,-1.44567,0.221079,0.00565569,1.00713 beta-lactamase_156_T186G,beta-lactamase_156_186,TEM-1,beta-lactamase_156,P62593,1.00714,NO,186,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.522,-2.403,-0.119,,0.396,H,A,0.22,-0.28,16.606,16.606,77.62,HPP,-1.77633,0.111618,0.00485034,1.00714 beta-lactamase_625_R273V,beta-lactamase_625_273,TEM-1,beta-lactamase_625,P62593,1.00714,NO,273,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.314,-3.626,1.312,,0.564,H,A,1.2,1.57,1.455,,73.78,ABP,-1.841,0.213352,0.0077952,1.00714 beta-lactamase_39_E195C,beta-lactamase_39_195,TEM-1,beta-lactamase_39,P62593,1.00715,NO,195,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.186,-5.238,3.052,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.0495842,0.00496565,1.00715 beta-lactamase_156_E87N,beta-lactamase_156_87,TEM-1,beta-lactamase_156,P62593,1.00716,NO,87,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.421,-3.684,2.263,,0.048,,B,1.04,0.92,1.754,,64.69,PAP,-1.969,0.111618,0.00337888,1.00716 beta-lactamase_2500_E87L,beta-lactamase_2500_87,TEM-1,beta-lactamase_2500,P62593,1.00716,NO,87,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.421,-2.529,1.108,,0.048,,B,1.04,0.92,17.923,17.923,64.69,PAP,-1.969,0.361275,0.00337888,1.00716 beta-lactamase_625_L196H,beta-lactamase_625_196,TEM-1,beta-lactamase_625,P62593,1.00717,NO,196,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-2.478,-3.478,1,,0.518,S,A,0.55,1.35,12.152,12.152,77.62,AHH,-1.839,0.213352,0.00512144,1.00717 beta-lactamase_M180V,beta-lactamase_180,TEM-1,beta-lactamase,P62593,1.00717,NO,180,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-2.795,-3.273,0.478,4.96809,0.242,,B,1.07,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.221079,0.00552048,1.00717 beta-lactamase_T186Q,beta-lactamase_186,TEM-1,beta-lactamase,P62593,1.00717,NO,186,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.522,-2.514,-0.008,5.07364,0.396,H,A,0.3,-0.28,2.144,,77.62,HPP,-1.77633,0.221079,0.00485034,1.00717 PSD95pdz3_Q374A,PSD95pdz3_374,PSD95pdz3,PSD95pdz3,P31016,1.00717,NO,374,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-1.699,-2.759,1.06,5.38825,,,,,17.3289,,,,APH,-1.47,0.0758425,0.000372298,1.00717 beta-lactamase_156_A222W,beta-lactamase_156_222,TEM-1,beta-lactamase_156,P62593,1.00718,NO,222,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.103,-5.409,3.306,,0.233,H,A,0.46,-0.25,2.461,,77.62,PHH,-1.63733,0.111618,0.00466094,1.00718 beta-lactamase_156_L55I,beta-lactamase_156_55,TEM-1,beta-lactamase_156,P62593,1.00718,NO,55,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.86,-2.434,0.574,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.111618,0.00403741,1.00718 beta-lactamase_2500_I140L,beta-lactamase_2500_140,TEM-1,beta-lactamase_2500,P62593,1.00718,NO,140,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.733,-1.622,-0.111,,0.128,H,A,0.48,0.41,1.628,,73.08,PHO,-1.48733,0.361275,0.00597777,1.00718 beta-lactamase_39_T112S,beta-lactamase_39_112,TEM-1,beta-lactamase_39,P62593,1.00718,NO,112,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.186,-2.762,0.576,,0.921,T,A,0.22,1.06,2.87,,73.78,HPA,-1.925,0.0495842,0.00531334,1.00718 beta-lactamase_156_E87H,beta-lactamase_156_87,TEM-1,beta-lactamase_156,P62593,1.00719,NO,87,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.421,-4.575,3.154,,0.048,,B,1.04,0.92,1.754,,64.69,PAP,-1.969,0.111618,0.00337888,1.00719 beta-lactamase_156_L188I,beta-lactamase_156_188,TEM-1,beta-lactamase_156,P62593,1.00719,NO,188,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.166,-2.584,1.418,,,H,A,0.55,-0.3,1.574,,60.14,PHB,-1.47033,0.111618,0.00295687,1.00719 beta-lactamase_39_S122T,beta-lactamase_39_122,TEM-1,beta-lactamase_39,P62593,1.00719,NO,122,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.406,-2.952,0.546,,0.352,H,A,0.27,-0.54,2.004,,77.62,OPH,-1.39767,0.0495842,0.00497825,1.00719 beta-lactamase_39_S256R,beta-lactamase_39_256,TEM-1,beta-lactamase_39,P62593,1.00719,NO,256,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.0495842,0.00710634,1.00719 beta-lactamase_39_L47K,beta-lactamase_39_47,TEM-1,beta-lactamase_39,P62593,1.0072,NO,47,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.876,-3.656,1.78,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.0495842,0.00439844,1.0072 Pab1_E161V,Pab1_161,Pab1,Pab1,P04147,1.0072,NO,161,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.474,-3.484,2.01,,0.663,T,a,,1.34,,,,AAP,-1.59067,0.175299,0.00276141,1.0072 beta-lactamase_2500_D252R,beta-lactamase_2500_252,TEM-1,beta-lactamase_2500,P62593,1.00722,NO,252,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.94,,,,0.766,,B,1.59,1.16,,,67.83,OAO,-2.0965,0.361275,0.00575769,1.00722 beta-lactamase_625_L74M,beta-lactamase_625_74,TEM-1,beta-lactamase_625,P62593,1.00722,NO,74,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.296,-2.987,1.691,,,H,A,0.55,-0.91,0.895,,50,HHO,-1.34933,0.213352,0.00493255,1.00722 beta-lactamase_39_Q86I,beta-lactamase_39_86,TEM-1,beta-lactamase_39,P62593,1.00723,NO,86,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.4,-3.877,1.477,,0.696,S,A,0.64,2.38,27.704,27.704,77.62,OPA,-1.61067,0.0495842,0.00450027,1.00723 beta-lactamase_625_T186A,beta-lactamase_625_186,TEM-1,beta-lactamase_625,P62593,1.00723,NO,186,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.522,-1.898,-0.624,,0.396,H,A,0.22,-0.28,0.515,,77.62,HPP,-1.77633,0.213352,0.00485034,1.00723 kka2_1:8_S104V,kka2_1:8_104,Kka2,kka2_1:8,P00552,1.00723,NO,104,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.436,-2.726,1.29,,0.536,T,A,0.27,-1.11,1.689,,63.64,HPP,-1.91433,0.100394,0.00555207,1.00723 kka2_1:8_S104V,kka2_1:8_104,Kka2,kka2_1:8,P00552,1.00723,NO,104,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.436,-2.726,1.29,,0.536,T,A,0.27,-1.11,1.689,,63.64,HPP,-1.91433,0.100394,0.00555207,1.00723 beta-lactamase_Q97H,beta-lactamase_97,TEM-1,beta-lactamase,P62593,1.00724,NO,97,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.072,-4.636,2.564,6.30204,0.823,G,A,1.1,2.42,1.157,,77.62,PPP,-2.43833,0.221079,0.0045116,1.00724 beta-lactamase_625_A246C,beta-lactamase_625_246,TEM-1,beta-lactamase_625,P62593,1.00725,NO,246,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.121,-3.242,1.121,,0.01,E,B,0.46,-1.01,1.201,,73.78,HHH,-1.55633,0.213352,0.00569458,1.00725 beta-lactamase_39_N168S,beta-lactamase_39_168,TEM-1,beta-lactamase_39,P62593,1.00726,NO,168,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-1.029,-2.37,1.341,,0.113,G,A,0.61,-0.4,0.822,,44.41,HPA,-1.13233,0.0495842,0.00288667,1.00726 beta-lactamase_625_R239F,beta-lactamase_625_239,TEM-1,beta-lactamase_625,P62593,1.00726,NO,239,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.213352,0.00213852,1.00726 beta-lactamase_156_T193A,beta-lactamase_156_193,TEM-1,beta-lactamase_156,P62593,1.00727,NO,193,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.914,-2.618,0.704,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.111618,0.00482669,1.00727 beta-lactamase_39_L223P,beta-lactamase_39_223,TEM-1,beta-lactamase_39,P62593,1.00728,NO,223,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.055,-4.101,3.046,,0.27,,B,0.55,0.09,1.511,,74.48,HHO,-1.35033,0.0495842,0.00372793,1.00728 beta-lactamase_625_E61L,beta-lactamase_625_61,TEM-1,beta-lactamase_625,P62593,1.00728,NO,61,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.115,-3.769,1.654,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.213352,0.00440955,1.00728 Pab1_G177A,Pab1_177,Pab1,Pab1,P04147,1.00728,NO,177,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-2.24,-2.247,0.007,,,,,,,,,,AOH,-1.94067,0.175299,0.00170727,1.00728 beta-lactamase_39_R162S,beta-lactamase_39_162,TEM-1,beta-lactamase_39,P62593,1.00729,NO,162,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.016,-3.456,2.44,,0.124,S,B,1.2,-0.37,31.656,31.656,64.69,ABH,-1.25,0.0495842,0.000561334,1.00729 beta-lactamase_39_T158F,beta-lactamase_39_158,TEM-1,beta-lactamase_39,P62593,1.00729,NO,158,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.116,-4.177,3.061,,0.036,,B,0.22,-0.85,2.755,,69.58,HPB,-1.269,0.0495842,0.00341825,1.00729 beta-lactamase_156_R162E,beta-lactamase_156_162,TEM-1,beta-lactamase_156,P62593,1.0073,NO,162,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.016,-3.337,2.321,,0.124,S,B,1.2,-0.37,7.444,,64.69,ABH,-1.25,0.111618,0.000561334,1.0073 beta-lactamase_2500_T139S,beta-lactamase_2500_139,TEM-1,beta-lactamase_2500,P62593,1.0073,NO,139,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.901,-2.265,0.364,,0.216,H,A,0.22,0.39,2.256,,77.62,PPH,-2.04667,0.361275,0.00441837,1.0073 beta-lactamase_39_E210R,beta-lactamase_39_210,TEM-1,beta-lactamase_39,P62593,1.0073,NO,210,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.319,-3.045,0.726,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.0495842,0.00663582,1.0073 beta-lactamase_39_P60G,beta-lactamase_39_60,TEM-1,beta-lactamase_39,P62593,1.0073,NO,60,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-2.469,-2.095,-0.374,,0.256,T,A,0.52,-0.56,21.37,21.37,77.62,BOA,-1.97633,0.0495842,0.00521318,1.0073 beta-lactamase_A148K,beta-lactamase_148,TEM-1,beta-lactamase,P62593,1.0073,NO,148,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.757,-2.857,1.1,5.28111,0.379,H,A,0.52,-0.55,2.117,,72.73,PHH,-1.40167,0.221079,0.00547053,1.0073 beta-lactamase_E195G,beta-lactamase_195,TEM-1,beta-lactamase,P62593,1.0073,NO,195,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.186,-2.611,0.425,7.28489,1.016,S,A,1.52,0.85,2.583,,77.62,OAH,-2.02,0.221079,0.00496565,1.0073 beta-lactamase_K109Q,beta-lactamase_109,TEM-1,beta-lactamase,P62593,1.0073,NO,109,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.734,-2.855,1.121,6.05842,0.787,G,A,1.82,2.21,21.623,21.623,72.73,ABB,-1.63333,0.221079,0.00462493,1.0073 beta-lactamase_K190S,beta-lactamase_190,TEM-1,beta-lactamase,P62593,1.0073,NO,190,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.994,-2.653,0.659,5.49163,0.371,H,A,1.82,0.16,29.753,29.753,77.62,BBH,-1.64167,0.221079,0.00574527,1.0073 beta-lactamase_M153L,beta-lactamase_153,TEM-1,beta-lactamase,P62593,1.0073,NO,153,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-3.193,-1.8,-1.393,5.46509,0.14,T,A,1.07,-0.11,2.061,,77.62,PHO,-2.25767,0.221079,0.00509109,1.0073 beta-lactamase_P60K,beta-lactamase_60,TEM-1,beta-lactamase,P62593,1.0073,NO,60,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-2.469,-3.557,1.088,5.51353,0.256,T,A,0.73,-0.56,3.653,,77.62,BOA,-1.97633,0.221079,0.00521318,1.0073 beta-lactamase_Q204T,beta-lactamase_204,TEM-1,beta-lactamase,P62593,1.0073,NO,204,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-1.382,-3.549,2.167,5.46394,0.204,H,A,0.12,0.09,1.707,,66.08,PPH,-1.49067,0.221079,0.00364106,1.0073 beta-lactamase_S122Y,beta-lactamase_122,TEM-1,beta-lactamase,P62593,1.0073,NO,122,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.406,-4.156,1.75,4.87767,0.352,H,A,0.73,-0.54,1.581,,77.62,OPH,-1.39767,0.221079,0.00497825,1.0073 beta-lactamase_156_K144T,beta-lactamase_156_144,TEM-1,beta-lactamase_156,P62593,1.00731,NO,144,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-2.388,-2.935,0.547,,0.863,H,A,2.34,1.27,2.073,,77.62,OBA,-1.904,0.111618,0.00481141,1.00731 beta-lactamase_2500_L47I,beta-lactamase_2500_47,TEM-1,beta-lactamase_2500,P62593,1.00731,NO,47,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.876,-2.384,0.508,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.361275,0.00439844,1.00731 beta-lactamase_39_E238A,beta-lactamase_39_238,TEM-1,beta-lactamase_39,P62593,1.00731,NO,238,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.0495842,0.00743256,1.00731 beta-lactamase_156_V214T,beta-lactamase_156_214,TEM-1,beta-lactamase_156,P62593,1.00732,NO,214,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.299,-1.73,0.431,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.111618,0.00628442,1.00732 beta-lactamase_39_T27R,beta-lactamase_39_27,TEM-1,beta-lactamase_39,P62593,1.00732,NO,27,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.905,-3.861,1.956,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.0495842,0.00306559,1.00732 beta-lactamase_39_V259S,beta-lactamase_39_259,TEM-1,beta-lactamase_39,P62593,1.00732,NO,259,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.0495842,0.0070773,1.00732 beta-lactamase_625_I245A,beta-lactamase_625_245,TEM-1,beta-lactamase_625,P62593,1.00732,NO,245,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.068,-3.611,2.543,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.213352,0.00391032,1.00732 beta-lactamase_156_F228W,beta-lactamase_156_228,TEM-1,beta-lactamase_156,P62593,1.00733,NO,228,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-2.342,-5.275,2.933,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.111618,0.0046669,1.00733 beta-lactamase_156_R273S,beta-lactamase_156_273,TEM-1,beta-lactamase_156,P62593,1.00733,NO,273,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.314,-3.326,1.012,,0.564,H,A,1.2,1.57,20.248,20.248,73.78,ABP,-1.841,0.111618,0.0077952,1.00733 beta-lactamase_2500_D252S,beta-lactamase_2500_252,TEM-1,beta-lactamase_2500,P62593,1.00733,NO,252,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.94,,,,0.766,,B,1.59,1.16,,,67.83,OAO,-2.0965,0.361275,0.00575769,1.00733 kka2_1:4_G88S,kka2_1:4_88,Kka2,kka2_1:4,P00552,1.00733,NO,88,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.689,-2.938,1.249,,0.54,S,l,0.29,1.51,7.899,,65.53,HOB,-1.718,0.168804,0.00685559,1.00733 PSD95pdz3_L360F,PSD95pdz3_360,PSD95pdz3,PSD95pdz3,P31016,1.00733,NO,360,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.431,-3.394,1.963,5.09284,,,,,14.2425,1.419,,86.88,HHP,-1.52667,0.0758425,0.000770471,1.00733 beta-lactamase_0_G249M,beta-lactamase_0_249,TEM-1,beta-lactamase_0,P62593,1.00734,NO,249,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.0500837,0.00220169,1.00734 beta-lactamase_156_D207I,beta-lactamase_156_207,TEM-1,beta-lactamase_156,P62593,1.00734,NO,207,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.064,-4.165,2.101,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.111618,0.00592942,1.00734 beta-lactamase_156_Q267D,beta-lactamase_156_267,TEM-1,beta-lactamase_156,P62593,1.00734,NO,267,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.111618,0.0102128,1.00734 beta-lactamase_156_Q97F,beta-lactamase_156_97,TEM-1,beta-lactamase_156,P62593,1.00734,NO,97,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.072,-4.44,2.368,,0.823,G,A,0.64,2.42,4.457,,77.62,PPP,-2.43833,0.111618,0.0045116,1.00734 beta-lactamase_625_M66I,beta-lactamase_625_66,TEM-1,beta-lactamase_625,P62593,1.00734,NO,66,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.362,-2.521,1.159,,0.013,,A,0.55,-0.7,1.659,,73.08,OHH,-1.49567,0.213352,0.00412876,1.00734 beta-lactamase_39_H151R,beta-lactamase_39_151,TEM-1,beta-lactamase_39,P62593,1.00735,NO,151,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-2.96,-1.217,-1.743,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.0495842,0.00216946,1.00735 beta-lactamase_625_Q97P,beta-lactamase_625_97,TEM-1,beta-lactamase_625,P62593,1.00735,NO,97,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.072,-2.583,0.511,,0.823,G,A,0.64,2.42,16.954,16.954,77.62,PPP,-2.43833,0.213352,0.0045116,1.00735 beta-lactamase_625_T116E,beta-lactamase_625_116,TEM-1,beta-lactamase_625,P62593,1.00735,NO,116,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.28,-3.469,2.189,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.213352,0.00336175,1.00735 beta-lactamase_156_W163Q,beta-lactamase_156_163,TEM-1,beta-lactamase_156,P62593,1.00736,NO,163,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-1.843,-2.929,1.086,,0.467,,B,0.47,-0.5,15.095,15.095,63.99,BHA,-1.269,0.111618,0.00418955,1.00736 beta-lactamase_39_K286H,beta-lactamase_39_286,TEM-1,beta-lactamase_39,P62593,1.00736,NO,286,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.0495842,,1.00736 beta-lactamase_39_V29G,beta-lactamase_39_29,TEM-1,beta-lactamase_39,P62593,1.00736,NO,29,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-2.856,-2.66,-0.196,,0.733,H,A,0.44,-0.78,1.287,,93.01,HHB,-2.24733,0.0495842,0.00318969,1.00736 beta-lactamase_39_W163Q,beta-lactamase_39_163,TEM-1,beta-lactamase_39,P62593,1.00736,NO,163,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-1.843,-2.929,1.086,,0.467,,B,0.47,-0.5,15.095,15.095,63.99,BHA,-1.269,0.0495842,0.00418955,1.00736 beta-lactamase_0_Q37C,beta-lactamase_0_37,TEM-1,beta-lactamase_0,P62593,1.00737,NO,37,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.134,-5.133,2.999,,0.613,H,A,0.64,1.98,4.001,,73.08,APH,-2.06967,0.0500837,0.00425833,1.00737 beta-lactamase_156_E145C,beta-lactamase_156_145,TEM-1,beta-lactamase_156,P62593,1.00737,NO,145,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.357,-5.044,2.687,,0.545,H,A,1.04,0.79,3.661,,77.62,BAH,-2.069,0.111618,0.00553285,1.00737 beta-lactamase_156_M66T,beta-lactamase_156_66,TEM-1,beta-lactamase_156,P62593,1.00737,NO,66,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.362,-3.498,2.136,,0.013,,A,0.55,-0.7,1.94,,73.08,OHH,-1.49567,0.111618,0.00412876,1.00737 beta-lactamase_156_T263Y,beta-lactamase_156_263,TEM-1,beta-lactamase_156,P62593,1.00737,NO,263,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.111618,0.0110582,1.00737 beta-lactamase_39_E35N,beta-lactamase_39_35,TEM-1,beta-lactamase_39,P62593,1.00737,NO,35,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-0.869,-3.445,2.576,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.0495842,0.00174441,1.00737 beta-lactamase_156_L192H,beta-lactamase_156_192,TEM-1,beta-lactamase_156,P62593,1.00738,NO,192,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.254,-4.926,3.672,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.111618,0.00558728,1.00738 beta-lactamase_2500_A148E,beta-lactamase_2500_148,TEM-1,beta-lactamase_2500,P62593,1.00738,NO,148,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.757,-2.317,0.56,,0.379,H,A,0.46,-0.55,2.117,,72.73,PHH,-1.40167,0.361275,0.00547053,1.00738 beta-lactamase_2500_T193H,beta-lactamase_2500_193,TEM-1,beta-lactamase_2500,P62593,1.00738,NO,193,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.914,-4.78,2.866,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.361275,0.00482669,1.00738 beta-lactamase_39_G194F,beta-lactamase_39_194,TEM-1,beta-lactamase_39,P62593,1.00739,NO,194,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.396,-4.382,2.986,,0.276,S,b,0.29,0.36,4.852,,67.83,POA,-1.832,0.0495842,0.00392163,1.00739 beta-lactamase_625_S221R,beta-lactamase_625_221,TEM-1,beta-lactamase_625,P62593,1.00739,NO,221,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.754,-2.83,1.076,,0.624,H,A,0.27,-0.2,1.495,,74.48,BPH,-1.59967,0.213352,0.0046094,1.00739 beta-lactamase_625_A225D,beta-lactamase_625_225,TEM-1,beta-lactamase_625,P62593,1.0074,NO,225,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.845,-2.561,0.716,,1,T,B,0.46,-0.38,9.874,9.874,74.48,OHO,-1.39967,0.213352,0.00465057,1.0074 beta-lactamase_T186H,beta-lactamase_186,TEM-1,beta-lactamase,P62593,1.0074,NO,186,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.522,-4.717,2.195,5.07364,0.396,H,A,0.3,-0.28,2.144,,77.62,HPP,-1.77633,0.221079,0.00485034,1.0074 kka2_1:4_I246T,kka2_1:4_246,Kka2,kka2_1:4,P00552,1.0074,NO,246,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-2.008,-3.038,1.03,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.168804,0.0139479,1.0074 beta-lactamase_39_R242V,beta-lactamase_39_242,TEM-1,beta-lactamase_39,P62593,1.00741,NO,242,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.0495842,0.00452879,1.00741 beta-lactamase_I171S,beta-lactamase_171,TEM-1,beta-lactamase,P62593,1.00741,NO,171,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-2.431,-2.869,0.438,5.22771,0.361,,B,1,0.53,1.66,,77.62,HHO,-1.55533,0.221079,0.00623355,1.00741 beta-lactamase_0_A211H,beta-lactamase_0_211,TEM-1,beta-lactamase_0,P62593,1.00742,NO,211,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.896,-3.336,1.44,,0.369,T,A,0.46,-0.69,8.527,8.527,77.62,AHA,-1.94633,0.0500837,0.00648183,1.00742 beta-lactamase_156_N152W,beta-lactamase_156_152,TEM-1,beta-lactamase_156,P62593,1.00742,NO,152,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-2.757,-5.472,2.715,,0.863,H,A,0.61,0.92,4.038,,77.62,BPH,-2.97,0.111618,0.00471429,1.00742 beta-lactamase_39_I93F,beta-lactamase_39_93,TEM-1,beta-lactamase_39,P62593,1.00742,NO,93,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.401,-3.88,2.479,,0.128,E,B,0.48,0.44,1.757,,67.83,BHB,-1.873,0.0495842,0.00527066,1.00742 beta-lactamase_625_L150C,beta-lactamase_625_150,TEM-1,beta-lactamase_625,P62593,1.00742,NO,150,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.326,-4.732,3.406,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.213352,0.00463171,1.00742 beta-lactamase_625_N50K,beta-lactamase_625_50,TEM-1,beta-lactamase_625,P62593,1.00742,NO,50,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-2.979,-3.578,0.599,,0.912,T,A,0.61,1.24,3.446,,77.62,HPP,-2.134,0.213352,0.0047211,1.00742 beta-lactamase_39_P217C,beta-lactamase_39_217,TEM-1,beta-lactamase_39,P62593,1.00743,NO,217,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-2.062,-5.064,3.002,,0.496,I,A,0.52,-0.33,21.172,21.172,74.48,OOH,-1.64333,0.0495842,0.00463211,1.00743 beta-lactamase_625_L137F,beta-lactamase_625_137,TEM-1,beta-lactamase_625,P62593,1.00743,NO,137,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.03,-3.682,2.652,,,H,A,0.55,-0.38,1.5,,42.31,HHP,-1.58933,0.213352,0.00278599,1.00743 PSD95pdz3_F340S,PSD95pdz3_340,PSD95pdz3,PSD95pdz3,P31016,1.00743,NO,340,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.524,-3.292,1.768,5.79283,,,,,11.8045,,,,PHH,-1.55767,0.0758425,0.000836987,1.00743 beta-lactamase_156_L196N,beta-lactamase_156_196,TEM-1,beta-lactamase_156,P62593,1.00744,NO,196,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-2.478,-3.953,1.475,,0.518,S,A,0.55,1.35,7.897,,77.62,AHH,-1.839,0.111618,0.00512144,1.00744 beta-lactamase_156_W163T,beta-lactamase_156_163,TEM-1,beta-lactamase_156,P62593,1.00744,NO,163,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-1.843,-2.765,0.922,,0.467,,B,0.47,-0.5,15.095,15.095,63.99,BHA,-1.269,0.111618,0.00418955,1.00744 beta-lactamase_39_A77S,beta-lactamase_39_77,TEM-1,beta-lactamase_39,P62593,1.00744,NO,77,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.234,-2.62,1.386,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.0495842,0.00282362,1.00744 beta-lactamase_625_G39E,beta-lactamase_625_39,TEM-1,beta-lactamase_625,P62593,1.00744,NO,39,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.864,-2.833,0.969,,0.701,T,L,0.29,0.47,29.926,29.926,77.62,HOH,-1.53633,0.213352,0.00487611,1.00744 beta-lactamase_625_H151Q,beta-lactamase_625_151,TEM-1,beta-lactamase_625,P62593,1.00744,NO,151,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-2.96,-2.497,-0.463,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.213352,0.00216946,1.00744 beta-lactamase_M180H,beta-lactamase_180,TEM-1,beta-lactamase,P62593,1.00744,NO,180,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-2.795,-4.627,1.832,4.96809,0.242,,B,1.07,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.221079,0.00552048,1.00744 beta-lactamase_0_E145V,beta-lactamase_0_145,TEM-1,beta-lactamase_0,P62593,1.00745,NO,145,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.357,-3.665,1.308,,0.545,H,A,1.04,0.79,1.199,,77.62,BAH,-2.069,0.0500837,0.00553285,1.00745 beta-lactamase_156_W208H,beta-lactamase_156_208,TEM-1,beta-lactamase_156,P62593,1.00745,NO,208,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-0.818,-4.68,3.862,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.111618,0.00126609,1.00745 beta-lactamase_625_A200T,beta-lactamase_625_200,TEM-1,beta-lactamase_625,P62593,1.00745,NO,200,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.878,-2.493,0.615,,0.757,H,A,0.46,-0.19,12.672,12.672,77.62,HHP,-2.001,0.213352,0.0060056,1.00745 beta-lactamase_625_G216K,beta-lactamase_625_216,TEM-1,beta-lactamase_625,P62593,1.00745,NO,216,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.477,-2.765,1.288,,0.437,I,A,0.29,-0.58,1.718,,74.48,HOO,-1.68067,0.213352,0.00639568,1.00745 beta-lactamase_2500_R92K,beta-lactamase_2500_92,TEM-1,beta-lactamase_2500,P62593,1.00746,NO,92,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.718,-2.258,0.54,,0.479,E,B,1.2,1.36,3.069,,65.38,BBH,-1.50367,0.361275,0.00429626,1.00746 beta-lactamase_625_F149I,beta-lactamase_625_149,TEM-1,beta-lactamase_625,P62593,1.00746,NO,149,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.299,-3.576,2.277,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.213352,0.00418462,1.00746 beta-lactamase_625_S122R,beta-lactamase_625_122,TEM-1,beta-lactamase_625,P62593,1.00747,NO,122,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.406,-3.131,0.725,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.213352,0.00497825,1.00747 kka2_1:8_G181C,kka2_1:8_181,Kka2,kka2_1:8,P00552,1.00747,NO,181,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-2.698,-5.203,2.505,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.100394,0.00728319,1.00747 kka2_1:8_G181C,kka2_1:8_181,Kka2,kka2_1:8,P00552,1.00747,NO,181,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-2.698,-5.203,2.505,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.100394,0.00728319,1.00747 Pab1_K140R,Pab1_140,Pab1,Pab1,P04147,1.00747,NO,140,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.083,-2.85,1.767,,0.345,H,A,,-0.73,,,,PBH,-1.20767,0.175299,0.000337366,1.00747 beta-lactamase_156_P60K,beta-lactamase_156_60,TEM-1,beta-lactamase_156,P62593,1.00748,NO,60,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-2.469,-3.557,1.088,,0.256,T,A,0.52,-0.56,2.947,,77.62,BOA,-1.97633,0.111618,0.00521318,1.00748 Pab1_D160C,Pab1_160,Pab1,Pab1,P04147,1.00748,NO,160,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.985,-4.904,3.919,,0.396,B,B,,1.12,,,,PAA,-1.30133,0.175299,0.000311977,1.00748 beta-lactamase_39_L89P,beta-lactamase_39_89,TEM-1,beta-lactamase_39,P62593,1.00749,NO,89,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.096,-2.221,1.125,,0.168,T,A,0.55,0.63,3.233,,64.34,PHO,-1.75767,0.0495842,0.00207068,1.00749 beta-lactamase_39_V259E,beta-lactamase_39_259,TEM-1,beta-lactamase_39,P62593,1.00749,NO,259,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.0495842,0.0070773,1.00749 kka2_1:8_P167N,kka2_1:8_167,Kka2,kka2_1:8,P00552,1.00749,NO,167,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-2.403,-3.993,1.59,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.100394,0.00543203,1.00749 kka2_1:8_P167N,kka2_1:8_167,Kka2,kka2_1:8,P00552,1.00749,NO,167,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-2.403,-3.993,1.59,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.100394,0.00543203,1.00749 beta-lactamase_156_D271I,beta-lactamase_156_271,TEM-1,beta-lactamase_156,P62593,1.0075,NO,271,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.111618,0.00752082,1.0075 beta-lactamase_156_Q88N,beta-lactamase_156_88,TEM-1,beta-lactamase_156,P62593,1.0075,NO,88,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.086,-2.735,0.649,,0.807,,B,0.64,2.03,0.911,,77.62,APH,-1.53433,0.111618,0.00504167,1.0075 beta-lactamase_39_S57F,beta-lactamase_39_57,TEM-1,beta-lactamase_39,P62593,1.0075,NO,57,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.918,-4.274,2.356,,0.352,E,B,0.27,-0.18,2.3,,72.73,APH,-2.29167,0.0495842,0.00492804,1.0075 kka2_1:8_A14W,kka2_1:8_14,Kka2,kka2_1:8,P00552,1.0075,NO,14,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.837,-5.518,3.681,,0.728,G,A,0.46,0.7,,,71.59,HHH,-1.82567,0.100394,0.00706614,1.0075 kka2_1:8_A14W,kka2_1:8_14,Kka2,kka2_1:8,P00552,1.0075,NO,14,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.837,-5.518,3.681,,0.728,G,A,0.46,0.7,,,71.59,HHH,-1.82567,0.100394,0.00706614,1.0075 beta-lactamase_2500_Q267S,beta-lactamase_2500_267,TEM-1,beta-lactamase_2500,P62593,1.00751,NO,267,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.361275,0.0102128,1.00751 beta-lactamase_39_R242T,beta-lactamase_39_242,TEM-1,beta-lactamase_39,P62593,1.00751,NO,242,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.0495842,0.00452879,1.00751 beta-lactamase_625_R92Y,beta-lactamase_625_92,TEM-1,beta-lactamase_625,P62593,1.00751,NO,92,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.718,-4.31,2.592,,0.479,E,B,1.2,1.36,3.069,,65.38,BBH,-1.50367,0.213352,0.00429626,1.00751 beta-lactamase_156_L223R,beta-lactamase_156_223,TEM-1,beta-lactamase_156,P62593,1.00752,NO,223,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.055,-4.022,2.967,,0.27,,B,0.55,0.09,1.511,,74.48,HHO,-1.35033,0.111618,0.00372793,1.00752 beta-lactamase_39_L167Q,beta-lactamase_39_167,TEM-1,beta-lactamase_39,P62593,1.00752,NO,167,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.138,-4.038,2.9,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.0495842,0.00303566,1.00752 beta-lactamase_39_N168V,beta-lactamase_39_168,TEM-1,beta-lactamase_39,P62593,1.00752,NO,168,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-1.029,-3.632,2.603,,0.113,G,A,0.61,-0.4,0.822,,44.41,HPA,-1.13233,0.0495842,0.00288667,1.00752 beta-lactamase_625_L223A,beta-lactamase_625_223,TEM-1,beta-lactamase_625,P62593,1.00752,NO,223,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.055,-3.102,2.047,,0.27,,B,0.55,0.09,1.633,,74.48,HHO,-1.35033,0.213352,0.00372793,1.00752 kka2_1:8_L243W,kka2_1:8_243,Kka2,kka2_1:8,P00552,1.00752,NO,243,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-2.651,-5.55,2.899,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.100394,0.00884927,1.00752 kka2_1:8_L243W,kka2_1:8_243,Kka2,kka2_1:8,P00552,1.00752,NO,243,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-2.651,-5.55,2.899,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.100394,0.00884927,1.00752 beta-lactamase_156_E145G,beta-lactamase_156_145,TEM-1,beta-lactamase_156,P62593,1.00753,NO,145,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.357,-1.279,-1.078,,0.545,H,A,1.04,0.79,3.661,,77.62,BAH,-2.069,0.111618,0.00553285,1.00753 beta-lactamase_39_C121G,beta-lactamase_39_121,TEM-1,beta-lactamase_39,P62593,1.00753,NO,121,C,G,CG,Special,Special,5.07,3.29388,-1.77612,159,121,75,-46,108.5,60.1,-48.4,-0.953,-3.581,2.628,,,H,A,0.46,-0.81,7.644,,63.29,HOP,-1.46767,0.0495842,0.000744322,1.00753 beta-lactamase_625_K53A,beta-lactamase_625_53,TEM-1,beta-lactamase_625,P62593,1.00753,NO,53,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-2.313,-2.735,0.422,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.213352,0.00383383,1.00753 beta-lactamase_156_E61A,beta-lactamase_156_61,TEM-1,beta-lactamase_156,P62593,1.00754,NO,61,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.115,-2.668,0.553,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.111618,0.00440955,1.00754 beta-lactamase_156_L49W,beta-lactamase_156_49,TEM-1,beta-lactamase_156,P62593,1.00754,NO,49,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.897,-5.315,3.418,,0.131,T,A,0.55,0.04,3.112,,64.69,AHP,-1.99233,0.111618,0.00401477,1.00754 beta-lactamase_39_T131G,beta-lactamase_39_131,TEM-1,beta-lactamase_39,P62593,1.00754,NO,131,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.328,-3.298,1.97,,,H,A,0.22,-0.69,3.306,,67.48,PPH,-1.00867,0.0495842,0.00345886,1.00754 beta-lactamase_625_P250C,beta-lactamase_625_250,TEM-1,beta-lactamase_625,P62593,1.00754,NO,250,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.213352,0.00550899,1.00754 beta-lactamase_Q203T,beta-lactamase_203,TEM-1,beta-lactamase,P62593,1.00754,NO,203,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.168,-2.523,0.355,5.65296,0.47,H,A,0.12,-0.38,1.66,,65.38,BPP,-1.614,0.221079,0.00631514,1.00754 beta-lactamase_156_W163Y,beta-lactamase_156_163,TEM-1,beta-lactamase_156,P62593,1.00755,NO,163,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-1.843,-3.906,2.063,,0.467,,B,0.47,-0.5,15.095,15.095,63.99,BHA,-1.269,0.111618,0.00418955,1.00755 beta-lactamase_625_E119A,beta-lactamase_625_119,TEM-1,beta-lactamase_625,P62593,1.00755,NO,119,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.412,-2.242,0.83,,0.358,H,A,1.04,0.51,1.034,,63.99,BAH,-1.623,0.213352,0.00386966,1.00755 kka2_1:8_N200C,kka2_1:8_200,Kka2,kka2_1:8,P00552,1.00755,NO,200,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-2.446,-5.276,2.83,,0.756,T,L,0.43,-0.08,2.528,,64.39,APO,-2.08,0.100394,0.00838549,1.00755 kka2_1:8_N200C,kka2_1:8_200,Kka2,kka2_1:8,P00552,1.00755,NO,200,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-2.446,-5.276,2.83,,0.756,T,L,0.43,-0.08,2.528,,64.39,APO,-2.08,0.100394,0.00838549,1.00755 beta-lactamase_156_A183W,beta-lactamase_156_183,TEM-1,beta-lactamase_156,P62593,1.00756,NO,183,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.231,-5.466,4.235,,0.155,H,A,0.46,-0.91,23.859,23.859,77.62,HHH,-1.53367,0.111618,0.00296631,1.00756 beta-lactamase_39_E238Q,beta-lactamase_39_238,TEM-1,beta-lactamase_39,P62593,1.00756,NO,238,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.0495842,0.00743256,1.00756 beta-lactamase_39_P60M,beta-lactamase_39_60,TEM-1,beta-lactamase_39,P62593,1.00756,NO,60,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-2.469,-4.701,2.232,,0.256,T,A,0.52,-0.56,21.37,21.37,77.62,BOA,-1.97633,0.0495842,0.00521318,1.00756 beta-lactamase_39_T69A,beta-lactamase_39_69,TEM-1,beta-lactamase_39,P62593,1.00756,NO,69,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-0.973,-2.115,1.142,,,G,A,0.22,-1.24,4.194,,93.01,PPH,-1.01833,0.0495842,0.00127498,1.00756 beta-lactamase_625_G52S,beta-lactamase_625_52,TEM-1,beta-lactamase_625,P62593,1.00757,NO,52,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.149,-2.647,1.498,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.213352,0.00340138,1.00757 beta-lactamase_0_C75K,beta-lactamase_0_75,TEM-1,beta-lactamase_0,P62593,1.00758,NO,75,C,K,CK,Special,PositiveCharge,5.07,9.74,4.67,202,121,146,25,108.5,168.6,60.1,-1.245,-3.786,2.541,,,H,A,0.46,-0.87,2.256,,50,HOO,-1.24333,0.0500837,0.0034616,1.00758 beta-lactamase_T138S,beta-lactamase_138,TEM-1,beta-lactamase,P62593,1.00758,NO,138,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.506,-2.455,-0.051,5.52585,0.662,H,A,0.3,-0.03,30.445,30.445,73.78,HPP,-1.81233,0.221079,0.00487868,1.00758 beta-lactamase_625_E102K,beta-lactamase_625_102,TEM-1,beta-lactamase_625,P62593,1.00759,NO,102,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.118,-2.64,0.522,,0.722,S,B,1.04,1.82,1.336,,73.08,HAH,-1.581,0.213352,0.00486633,1.00759 beta-lactamase_0_L219W,beta-lactamase_0_219,TEM-1,beta-lactamase_0,P62593,1.0076,NO,219,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.313,-5.183,3.87,,,I,A,0.55,-0.51,6.513,6.513,74.48,HHB,-1.21533,0.0500837,0.00664345,1.0076 beta-lactamase_2500_S122G,beta-lactamase_2500_122,TEM-1,beta-lactamase_2500,P62593,1.0076,NO,122,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.406,-3.475,1.069,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.361275,0.00497825,1.0076 beta-lactamase_625_A84T,beta-lactamase_625_84,TEM-1,beta-lactamase_625,P62593,1.0076,NO,84,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.651,-2.88,1.229,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.213352,0.00503822,1.0076 beta-lactamase_625_Q97H,beta-lactamase_625_97,TEM-1,beta-lactamase_625,P62593,1.0076,NO,97,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.072,-4.636,2.564,,0.823,G,A,0.64,2.42,16.954,16.954,77.62,PPP,-2.43833,0.213352,0.0045116,1.0076 beta-lactamase_2500_S57A,beta-lactamase_2500_57,TEM-1,beta-lactamase_2500,P62593,1.00761,NO,57,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.918,-1.894,-0.024,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.361275,0.00492804,1.00761 beta-lactamase_39_L167V,beta-lactamase_39_167,TEM-1,beta-lactamase_39,P62593,1.00761,NO,167,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.138,-2.277,1.139,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.0495842,0.00303566,1.00761 beta-lactamase_39_R162A,beta-lactamase_39_162,TEM-1,beta-lactamase_39,P62593,1.00761,NO,162,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.016,-3.127,2.111,,0.124,S,B,1.2,-0.37,31.656,31.656,64.69,ABH,-1.25,0.0495842,0.000561334,1.00761 beta-lactamase_156_M270E,beta-lactamase_156_270,TEM-1,beta-lactamase_156,P62593,1.00762,NO,270,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.723,-4.709,2.986,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.111618,0.00767762,1.00762 beta-lactamase_39_D155E,beta-lactamase_39_155,TEM-1,beta-lactamase_39,P62593,1.00762,NO,155,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.889,-2.299,1.41,,0.049,,B,0.75,-0.9,3.208,,64.69,OAB,-1.62267,0.0495842,0.00135315,1.00762 beta-lactamase_39_F70K,beta-lactamase_39_70,TEM-1,beta-lactamase_39,P62593,1.00762,NO,70,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.169,-3.812,2.643,,,H,A,0.58,-1.34,1.14,,63.99,PHB,-0.980667,0.0495842,0.00193499,1.00762 beta-lactamase_A40G,beta-lactamase_40,TEM-1,beta-lactamase,P62593,1.00762,NO,40,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.402,-1.32,-0.082,4.9697,0.155,S,B,1.2,0.21,1.714,,73.78,OHB,-1.40267,0.221079,0.00490026,1.00762 beta-lactamase_0_T131I,beta-lactamase_0_131,TEM-1,beta-lactamase_0,P62593,1.00763,NO,131,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.328,-3.758,2.43,,,H,A,0.22,-0.69,3.306,,67.48,PPH,-1.00867,0.0500837,0.00345886,1.00763 beta-lactamase_156_T264W,beta-lactamase_156_264,TEM-1,beta-lactamase_156,P62593,1.00763,NO,264,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.111618,0.0119399,1.00763 beta-lactamase_625_L74T,beta-lactamase_625_74,TEM-1,beta-lactamase_625,P62593,1.00763,NO,74,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.296,-3.432,2.136,,,H,A,0.55,-0.91,0.895,,50,HHO,-1.34933,0.213352,0.00493255,1.00763 beta-lactamase_156_R91Q,beta-lactamase_156_91,TEM-1,beta-lactamase_156,P62593,1.00764,NO,91,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.392,-2.363,0.971,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.111618,0.00380226,1.00764 beta-lactamase_39_L192F,beta-lactamase_39_192,TEM-1,beta-lactamase_39,P62593,1.00764,NO,192,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.254,-2.572,1.318,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.0495842,0.00558728,1.00764 beta-lactamase_625_A124T,beta-lactamase_625_124,TEM-1,beta-lactamase_625,P62593,1.00764,NO,124,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.181,-1.586,0.405,,,H,A,0.46,-0.9,2.027,,64.34,HHH,-1.152,0.213352,0.00481399,1.00764 beta-lactamase_156_F58L,beta-lactamase_156_58,TEM-1,beta-lactamase_156,P62593,1.00765,NO,58,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-2.914,-3.474,0.56,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.111618,0.00523369,1.00765 beta-lactamase_156_L199F,beta-lactamase_156_199,TEM-1,beta-lactamase_156,P62593,1.00765,NO,199,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-2.942,-4.403,1.461,,0.832,H,A,0.55,0.42,1.552,,77.62,PHH,-2.32933,0.111618,0.0048649,1.00765 beta-lactamase_156_W163R,beta-lactamase_156_163,TEM-1,beta-lactamase_156,P62593,1.00765,NO,163,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-1.843,-2.51,0.667,,0.467,,B,0.47,-0.5,15.095,15.095,63.99,BHA,-1.269,0.111618,0.00418955,1.00765 beta-lactamase_156_A183H,beta-lactamase_156_183,TEM-1,beta-lactamase_156,P62593,1.00766,NO,183,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.231,-4.624,3.393,,0.155,H,A,0.46,-0.91,23.859,23.859,77.62,HHH,-1.53367,0.111618,0.00296631,1.00766 beta-lactamase_156_H24D,beta-lactamase_156_24,TEM-1,beta-lactamase_156,P62593,1.00766,NO,24,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-2.481,-2.42,-0.061,,,,,,,2.708,,93.01,OBO,-2.0035,0.111618,0.00238894,1.00766 beta-lactamase_156_I140T,beta-lactamase_156_140,TEM-1,beta-lactamase_156,P62593,1.00766,NO,140,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.733,-2.748,1.015,,0.128,H,A,0.48,0.41,1.16,,73.08,PHO,-1.48733,0.111618,0.00597777,1.00766 beta-lactamase_2500_R239Q,beta-lactamase_2500_239,TEM-1,beta-lactamase_2500,P62593,1.00766,NO,239,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.361275,0.00213852,1.00766 beta-lactamase_39_R118P,beta-lactamase_39_118,TEM-1,beta-lactamase_39,P62593,1.00766,NO,118,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.413,-3.946,1.533,,0.457,H,A,1.2,1.39,3.961,,77.62,HBA,-1.785,0.0495842,0.00538794,1.00766 beta-lactamase_625_F149R,beta-lactamase_625_149,TEM-1,beta-lactamase_625,P62593,1.00766,NO,149,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.299,-4.139,2.84,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.213352,0.00418462,1.00766 beta-lactamase_625_F70T,beta-lactamase_625_70,TEM-1,beta-lactamase_625,P62593,1.00766,NO,70,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.169,-3.571,2.402,,,H,A,0.58,-1.34,1.14,,63.99,PHB,-0.980667,0.213352,0.00193499,1.00766 beta-lactamase_625_Q97L,beta-lactamase_625_97,TEM-1,beta-lactamase_625,P62593,1.00766,NO,97,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.072,-3.528,1.456,,0.823,G,A,0.64,2.42,16.954,16.954,77.62,PPP,-2.43833,0.213352,0.0045116,1.00766 beta-lactamase_F228F,beta-lactamase_228,TEM-1,beta-lactamase,P62593,1.00766,NO,228,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-2.342,-2.342,,5.33448,0.154,E,B,1.1,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.221079,0.0046669,1.00766 beta-lactamase_156_I171A,beta-lactamase_156_171,TEM-1,beta-lactamase_156,P62593,1.00767,NO,171,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-2.431,-2.242,-0.189,,0.361,,B,0.48,0.53,3.869,,77.62,HHO,-1.55533,0.111618,0.00623355,1.00767 beta-lactamase_156_R118T,beta-lactamase_156_118,TEM-1,beta-lactamase_156,P62593,1.00767,NO,118,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.413,-2.845,0.432,,0.457,H,A,1.2,1.39,2.231,,77.62,HBA,-1.785,0.111618,0.00538794,1.00767 beta-lactamase_39_N152K,beta-lactamase_39_152,TEM-1,beta-lactamase_39,P62593,1.00767,NO,152,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-2.757,-2.892,0.135,,0.863,H,A,0.61,0.92,4.038,,77.62,BPH,-2.97,0.0495842,0.00471429,1.00767 beta-lactamase_156_E108W,beta-lactamase_156_108,TEM-1,beta-lactamase_156,P62593,1.00768,NO,108,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.46,-5.465,4.005,,0.572,G,A,1.04,1.87,8.602,8.602,72.73,PAB,-1.437,0.111618,0.00413372,1.00768 beta-lactamase_156_K53R,beta-lactamase_156_53,TEM-1,beta-lactamase_156,P62593,1.00768,NO,53,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-2.313,-2.027,-0.286,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.111618,0.00383383,1.00768 beta-lactamase_156_P250Q,beta-lactamase_156_250,TEM-1,beta-lactamase_156,P62593,1.00768,NO,250,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.111618,0.00550899,1.00768 beta-lactamase_2500_L49I,beta-lactamase_2500_49,TEM-1,beta-lactamase_2500,P62593,1.00768,NO,49,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.897,-3.523,1.626,,0.131,T,A,0.55,0.04,6.681,,64.69,AHP,-1.99233,0.361275,0.00401477,1.00768 beta-lactamase_39_K32Y,beta-lactamase_39_32,TEM-1,beta-lactamase_39,P62593,1.00768,NO,32,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.984,-4.317,2.333,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.0495842,0.00401283,1.00768 beta-lactamase_625_A77I,beta-lactamase_625_77,TEM-1,beta-lactamase_625,P62593,1.00768,NO,77,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.234,-3.583,2.349,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.213352,0.00282362,1.00768 beta-lactamase_625_E210G,beta-lactamase_625_210,TEM-1,beta-lactamase_625,P62593,1.00768,NO,210,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.319,-3.66,1.341,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.213352,0.00663582,1.00768 beta-lactamase_156_G141S,beta-lactamase_156_141,TEM-1,beta-lactamase_156,P62593,1.00769,NO,141,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.828,-3.221,2.393,,0.575,T,l,0.29,-0.28,0.198,,64.69,HOO,-1.08933,0.111618,0.0012419,1.00769 beta-lactamase_156_L100R,beta-lactamase_156_100,TEM-1,beta-lactamase_156,P62593,1.00769,NO,100,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.218,-4.123,2.905,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.111618,0.00413885,1.00769 beta-lactamase_39_A84C,beta-lactamase_39_84,TEM-1,beta-lactamase_39,P62593,1.00769,NO,84,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.651,-5.003,3.352,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.0495842,0.00503822,1.00769 beta-lactamase_39_M67T,beta-lactamase_39_67,TEM-1,beta-lactamase_39,P62593,1.00769,NO,67,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-2.231,-3.488,1.257,,0.006,G,P,0.55,-0.81,1.463,,65.03,HHP,-1.502,0.0495842,0.00409753,1.00769 beta-lactamase_625_K109S,beta-lactamase_625_109,TEM-1,beta-lactamase_625,P62593,1.00769,NO,109,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.734,-2.861,1.127,,0.787,G,A,2.34,2.21,7.243,,72.73,ABB,-1.63333,0.213352,0.00462493,1.00769 beta-lactamase_M180Y,beta-lactamase_180,TEM-1,beta-lactamase,P62593,1.00769,NO,180,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-2.795,-2.93,0.135,4.96809,0.242,,B,1.07,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.221079,0.00552048,1.00769 beta-lactamase_N152G,beta-lactamase_152,TEM-1,beta-lactamase,P62593,1.00769,NO,152,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-2.757,-2.26,-0.497,5.98571,0.863,H,A,0.09,0.92,2.061,,77.62,BPH,-2.97,0.221079,0.00471429,1.00769 beta-lactamase_S122Q,beta-lactamase_122,TEM-1,beta-lactamase,P62593,1.00769,NO,122,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.406,-2.914,0.508,4.87767,0.352,H,A,0.73,-0.54,1.581,,77.62,OPH,-1.39767,0.221079,0.00497825,1.00769 beta-lactamase_625_Q204L,beta-lactamase_625_204,TEM-1,beta-lactamase_625,P62593,1.0077,NO,204,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-1.382,-2.716,1.334,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.213352,0.00364106,1.0077 beta-lactamase_39_L47G,beta-lactamase_39_47,TEM-1,beta-lactamase_39,P62593,1.00771,NO,47,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.876,-3.777,1.901,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.0495842,0.00439844,1.00771 beta-lactamase_2500_F58H,beta-lactamase_2500_58,TEM-1,beta-lactamase_2500,P62593,1.00772,NO,58,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-2.914,-2.092,-0.822,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.361275,0.00523369,1.00772 beta-lactamase_625_S256D,beta-lactamase_625_256,TEM-1,beta-lactamase_625,P62593,1.00772,NO,256,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.213352,0.00710634,1.00772 beta-lactamase_156_K144N,beta-lactamase_156_144,TEM-1,beta-lactamase_156,P62593,1.00773,NO,144,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-2.388,-3.043,0.655,,0.863,H,A,2.34,1.27,2.073,,77.62,OBA,-1.904,0.111618,0.00481141,1.00773 beta-lactamase_625_K109W,beta-lactamase_625_109,TEM-1,beta-lactamase_625,P62593,1.00773,NO,109,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.734,-5.518,3.784,,0.787,G,A,2.34,2.21,7.243,,72.73,ABB,-1.63333,0.213352,0.00462493,1.00773 Pab1_P135L,Pab1_135,Pab1,Pab1,P04147,1.00773,NO,135,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.457,-3.361,1.904,,,,,,,6.41,,81.8,BOA,-1.53367,0.175299,0.00148028,1.00773 beta-lactamase_39_T263V,beta-lactamase_39_263,TEM-1,beta-lactamase_39,P62593,1.00774,NO,263,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.0495842,0.0110582,1.00774 kka2_1:8_P179N,kka2_1:8_179,Kka2,kka2_1:8,P00552,1.00774,NO,179,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.974,-3.967,2.993,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.100394,0.00298346,1.00774 kka2_1:8_P179N,kka2_1:8_179,Kka2,kka2_1:8,P00552,1.00774,NO,179,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.974,-3.967,2.993,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.100394,0.00298346,1.00774 beta-lactamase_156_M66V,beta-lactamase_156_66,TEM-1,beta-lactamase_156,P62593,1.00775,NO,66,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.362,-2.395,1.033,,0.013,,A,0.55,-0.7,1.94,,73.08,OHH,-1.49567,0.111618,0.00412876,1.00775 beta-lactamase_39_A182V,beta-lactamase_39_182,TEM-1,beta-lactamase_39,P62593,1.00775,NO,182,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.777,-2.556,0.779,,0.136,H,A,0.46,-0.66,2.598,,93.01,OHH,-1.27367,0.0495842,0.00559099,1.00775 beta-lactamase_39_A183P,beta-lactamase_39_183,TEM-1,beta-lactamase_39,P62593,1.00775,NO,183,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.231,-3.812,2.581,,0.155,H,A,0.46,-0.91,1.237,,77.62,HHH,-1.53367,0.0495842,0.00296631,1.00775 beta-lactamase_I171Y,beta-lactamase_171,TEM-1,beta-lactamase,P62593,1.00775,NO,171,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-2.431,-4.204,1.773,5.22771,0.361,,B,1,0.53,1.66,,77.62,HHO,-1.55533,0.221079,0.00623355,1.00775 beta-lactamase_156_A211F,beta-lactamase_156_211,TEM-1,beta-lactamase_156,P62593,1.00776,NO,211,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.896,-4.364,2.468,,0.369,T,A,0.46,-0.69,8.527,8.527,77.62,AHA,-1.94633,0.111618,0.00648183,1.00776 beta-lactamase_39_N168D,beta-lactamase_39_168,TEM-1,beta-lactamase_39,P62593,1.00776,NO,168,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-1.029,-3.143,2.114,,0.113,G,A,0.61,-0.4,0.822,,44.41,HPA,-1.13233,0.0495842,0.00288667,1.00776 beta-lactamase_625_T116V,beta-lactamase_625_116,TEM-1,beta-lactamase_625,P62593,1.00777,NO,116,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.28,-3.415,2.135,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.213352,0.00336175,1.00777 beta-lactamase_E169A,beta-lactamase_169,TEM-1,beta-lactamase,P62593,1.00777,NO,169,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.23,-2.486,1.256,5.78896,0.337,,A,0.52,1,1.806,,73.08,PAH,-1.16533,0.221079,0.00400994,1.00777 beta-lactamase_156_E102Y,beta-lactamase_156_102,TEM-1,beta-lactamase_156,P62593,1.00778,NO,102,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.118,-4.321,2.203,,0.722,S,B,1.04,1.82,15.721,15.721,73.08,HAH,-1.581,0.111618,0.00486633,1.00778 beta-lactamase_39_G236I,beta-lactamase_39_236,TEM-1,beta-lactamase_39,P62593,1.00778,NO,236,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.784,-4.139,3.355,,0.241,,b,0.29,-0.59,1.883,,64.69,HOO,-1.025,0.0495842,0.00162372,1.00778 beta-lactamase_625_P250S,beta-lactamase_625_250,TEM-1,beta-lactamase_625,P62593,1.00778,NO,250,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.213352,0.00550899,1.00778 beta-lactamase_N168N,beta-lactamase_168,TEM-1,beta-lactamase,P62593,1.00778,NO,168,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-1.029,-1.029,,5.42128,0.113,G,A,0.09,-0.4,1.211,,44.41,HPA,-1.13233,0.221079,0.00288667,1.00778 beta-lactamase_39_L188Y,beta-lactamase_39_188,TEM-1,beta-lactamase_39,P62593,1.00779,NO,188,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.166,-3.998,2.832,,,H,A,0.55,-0.3,2.982,,60.14,PHB,-1.47033,0.0495842,0.00295687,1.00779 kka2_1:2_T146Y,kka2_1:2_146,Kka2,kka2_1:2,P00552,1.00779,NO,146,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.978,-4.381,1.403,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.295029,0.00606474,1.00779 PSD95pdz3_Q384T,PSD95pdz3_384,PSD95pdz3,PSD95pdz3,P31016,1.00779,NO,384,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-1.699,-3.103,1.404,5.49339,,,,,23.54,,,,OPP,-1.41333,0.0758425,0.000216736,1.00779 beta-lactamase_156_A215K,beta-lactamase_156_215,TEM-1,beta-lactamase_156,P62593,1.0078,NO,215,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.503,-3.575,2.072,,,,a,0.46,-0.93,3.583,,74.48,HHO,-1.42633,0.111618,0.00544007,1.0078 beta-lactamase_156_W163D,beta-lactamase_156_163,TEM-1,beta-lactamase_156,P62593,1.0078,NO,163,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-1.843,-3.903,2.06,,0.467,,B,0.47,-0.5,15.095,15.095,63.99,BHA,-1.269,0.111618,0.00418955,1.0078 beta-lactamase_39_R239L,beta-lactamase_39_239,TEM-1,beta-lactamase_39,P62593,1.00783,NO,239,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.0495842,0.00213852,1.00783 beta-lactamase_K284S,beta-lactamase_284,TEM-1,beta-lactamase,P62593,1.00783,NO,284,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.981,-2.582,0.601,6.30084,0.848,H,A,1.82,0.67,1.931,,77.62,HBB,-1.82133,0.221079,0.0686156,1.00783 Pab1_G193S,Pab1_193,Pab1,Pab1,P04147,1.00783,NO,193,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.414,-3.045,1.631,,,,,,,,,,POP,-1.55733,0.175299,0.0014922,1.00783 beta-lactamase_156_A215F,beta-lactamase_156_215,TEM-1,beta-lactamase_156,P62593,1.00784,NO,215,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.503,-4.278,2.775,,,,a,0.46,-0.93,3.583,,74.48,HHO,-1.42633,0.111618,0.00544007,1.00784 beta-lactamase_625_E195R,beta-lactamase_625_195,TEM-1,beta-lactamase_625,P62593,1.00784,NO,195,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.186,-3.074,0.888,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.213352,0.00496565,1.00784 beta-lactamase_625_P60C,beta-lactamase_625_60,TEM-1,beta-lactamase_625,P62593,1.00784,NO,60,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-2.469,-4.889,2.42,,0.256,T,A,0.52,-0.56,3.653,,77.62,BOA,-1.97633,0.213352,0.00521318,1.00784 beta-lactamase_156_D99L,beta-lactamase_156_99,TEM-1,beta-lactamase_156,P62593,1.00785,NO,99,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.191,-3.588,2.397,,0.402,G,A,0.75,0.36,3.529,,64.69,PAH,-1.794,0.111618,0.00305446,1.00785 beta-lactamase_156_V78C,beta-lactamase_156_78,TEM-1,beta-lactamase_156,P62593,1.00785,NO,78,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.459,-4.812,3.353,,,H,A,0.44,-0.47,1.132,,63.64,HHH,-1.17833,0.111618,0.00492501,1.00785 beta-lactamase_156_H94L,beta-lactamase_156_94,TEM-1,beta-lactamase_156,P62593,1.00786,NO,94,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-2.5,-3.441,0.941,,0.776,,B,0.17,1.24,11.583,11.583,77.62,HBH,-1.872,0.111618,0.00389226,1.00786 beta-lactamase_2500_T186S,beta-lactamase_2500_186,TEM-1,beta-lactamase_2500,P62593,1.00786,NO,186,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.522,-2.471,-0.051,,0.396,H,A,0.22,-0.28,2.144,,77.62,HPP,-1.77633,0.361275,0.00485034,1.00786 beta-lactamase_625_D113I,beta-lactamase_625_113,TEM-1,beta-lactamase_625,P62593,1.00786,NO,113,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.829,-4.028,2.199,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.213352,0.00474112,1.00786 beta-lactamase_L135L,beta-lactamase_135,TEM-1,beta-lactamase,P62593,1.00786,NO,135,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.002,-1.002,,5.28497,0.117,H,A,1.07,-0.58,0.697,,43.71,PHH,-1.03767,0.221079,0.00244423,1.00786 beta-lactamase_156_K109G,beta-lactamase_156_109,TEM-1,beta-lactamase_156,P62593,1.00787,NO,109,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.734,-2.852,1.118,,0.787,G,A,2.34,2.21,6.031,,72.73,ABB,-1.63333,0.111618,0.00462493,1.00787 beta-lactamase_156_A170F,beta-lactamase_156_170,TEM-1,beta-lactamase_156,P62593,1.00788,NO,170,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.237,-2.633,1.396,,0.126,,L,0.46,-0.35,3.7,,64.69,AHH,-1.63267,0.111618,0.00431903,1.00788 beta-lactamase_39_I93D,beta-lactamase_39_93,TEM-1,beta-lactamase_39,P62593,1.00788,NO,93,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.401,-4.003,2.602,,0.128,E,B,0.48,0.44,1.757,,67.83,BHB,-1.873,0.0495842,0.00527066,1.00788 beta-lactamase_156_R242M,beta-lactamase_156_242,TEM-1,beta-lactamase_156,P62593,1.00789,NO,242,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.111618,0.00452879,1.00789 beta-lactamase_156_E145F,beta-lactamase_156_145,TEM-1,beta-lactamase_156,P62593,1.0079,NO,145,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.357,-4.373,2.016,,0.545,H,A,1.04,0.79,3.661,,77.62,BAH,-2.069,0.111618,0.00553285,1.0079 beta-lactamase_156_L284N,beta-lactamase_156_284,TEM-1,beta-lactamase_156,P62593,1.0079,NO,284,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.111618,0.0686156,1.0079 beta-lactamase_39_A268Q,beta-lactamase_39_268,TEM-1,beta-lactamase_39,P62593,1.0079,NO,268,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.0495842,0.0102525,1.0079 beta-lactamase_39_T147L,beta-lactamase_39_147,TEM-1,beta-lactamase_39,P62593,1.0079,NO,147,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.149,-3.242,2.093,,0.281,H,A,0.22,-0.68,13.843,13.843,64.34,HPH,-1.456,0.0495842,0.00226017,1.0079 beta-lactamase_625_E238G,beta-lactamase_625_238,TEM-1,beta-lactamase_625,P62593,1.0079,NO,238,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.213352,0.00743256,1.0079 beta-lactamase_39_P65L,beta-lactamase_39_65,TEM-1,beta-lactamase_39,P62593,1.00791,NO,65,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.894,-2.247,1.353,,0.098,E,B,0.52,-0.62,0.623,,40.56,HOH,-1.03233,0.0495842,0.00152776,1.00791 beta-lactamase_39_T269E,beta-lactamase_39_269,TEM-1,beta-lactamase_39,P62593,1.00791,NO,269,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.156,,,,0.646,H,A,0.53,0.4,3.889,,77.62,HPH,-1.96733,0.0495842,0.00950944,1.00791 beta-lactamase_625_P172E,beta-lactamase_625_172,TEM-1,beta-lactamase_625,P62593,1.00791,NO,172,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.998,-3.52,2.522,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.213352,0.00312594,1.00791 beta-lactamase_2500_A182M,beta-lactamase_2500_182,TEM-1,beta-lactamase_2500,P62593,1.00792,NO,182,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.777,-4.709,2.932,,0.136,H,A,0.46,-0.66,2.032,,93.01,OHH,-1.27367,0.361275,0.00559099,1.00792 beta-lactamase_39_L136I,beta-lactamase_39_136,TEM-1,beta-lactamase_39,P62593,1.00792,NO,136,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.232,-1.874,0.642,,,H,A,0.55,-0.34,0.336,,48.95,HHH,-1.088,0.0495842,0.00442304,1.00792 beta-lactamase_625_R273A,beta-lactamase_625_273,TEM-1,beta-lactamase_625,P62593,1.00793,NO,273,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.314,-1.856,-0.458,,0.564,H,A,1.2,1.57,1.455,,73.78,ABP,-1.841,0.213352,0.0077952,1.00793 beta-lactamase_156_V117A,beta-lactamase_156_117,TEM-1,beta-lactamase_156,P62593,1.00794,NO,117,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.53,-3.142,1.612,,,H,A,0.44,-0.34,1.182,,65.03,PHB,-1.741,0.111618,0.00467906,1.00794 beta-lactamase_39_S122A,beta-lactamase_39_122,TEM-1,beta-lactamase_39,P62593,1.00794,NO,122,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.406,-2.18,-0.226,,0.352,H,A,0.27,-0.54,2.004,,77.62,OPH,-1.39767,0.0495842,0.00497825,1.00794 beta-lactamase_156_G39S,beta-lactamase_156_39,TEM-1,beta-lactamase_156,P62593,1.00795,NO,39,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.864,-2.342,0.478,,0.701,T,L,0.29,0.47,1.454,,77.62,HOH,-1.53633,0.111618,0.00487611,1.00795 beta-lactamase_39_W163M,beta-lactamase_39_163,TEM-1,beta-lactamase_39,P62593,1.00795,NO,163,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-1.843,-3.104,1.261,,0.467,,B,0.47,-0.5,15.095,15.095,63.99,BHA,-1.269,0.0495842,0.00418955,1.00795 Pab1_G163R,Pab1_163,Pab1,Pab1,P04147,1.00795,NO,163,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.809,-3.75,2.941,,0.356,B,g,,0.55,,,,POB,-1.80667,0.175299,0.00030953,1.00795 beta-lactamase_0_N168H,beta-lactamase_0_168,TEM-1,beta-lactamase_0,P62593,1.00796,NO,168,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-1.029,-4.17,3.141,,0.113,G,A,0.61,-0.4,0.881,,44.41,HPA,-1.13233,0.0500837,0.00288667,1.00796 beta-lactamase_156_K109H,beta-lactamase_156_109,TEM-1,beta-lactamase_156,P62593,1.00796,NO,109,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.734,-3.369,1.635,,0.787,G,A,2.34,2.21,6.031,,72.73,ABB,-1.63333,0.111618,0.00462493,1.00796 E1_Ubiquitin_Q40P,E1_Ubiquitin_40,Uba1,E1_Ubiquitin,P0CG63,1.00796,NO,40,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-1.48,-3.608,2.128,,0.387,G,A,,0.03,,,,OPP,-1.365,0.18783,0.0037961,1.00796 E1_Ubiquitin_R42R,E1_Ubiquitin_42,Uba1,E1_Ubiquitin,P0CG63,1.00796,NO,42,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.302,-1.302,,,0.244,E,B,,-0.54,,,,PBH,-1.24667,0.18783,0.00224033,1.00796 E1_Ubiquitin_T68C,E1_Ubiquitin_68,Uba1,E1_Ubiquitin,P0CG63,1.00796,NO,68,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,,,,,,,,,,,,,OPH,-1.039,0.18783,0.00314321,1.00796 PSD95pdz3_R312E,PSD95pdz3_312,PSD95pdz3,PSD95pdz3,P31016,1.00796,NO,312,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.582,-2.897,1.315,5.76826,,,,,12.2409,,,,OBB,-1.46667,0.0758425,0.00196255,1.00796 beta-lactamase_156_A247M,beta-lactamase_156_247,TEM-1,beta-lactamase_156,P62593,1.00797,NO,247,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.111618,0.00611275,1.00797 beta-lactamase_156_E238N,beta-lactamase_156_238,TEM-1,beta-lactamase_156,P62593,1.00797,NO,238,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.111618,0.00743256,1.00797 beta-lactamase_156_I258M,beta-lactamase_156_258,TEM-1,beta-lactamase_156,P62593,1.00797,NO,258,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.111618,0.007931,1.00797 beta-lactamase_156_P60R,beta-lactamase_156_60,TEM-1,beta-lactamase_156,P62593,1.00797,NO,60,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-2.469,-3.014,0.545,,0.256,T,A,0.52,-0.56,2.947,,77.62,BOA,-1.97633,0.111618,0.00521318,1.00797 beta-lactamase_39_L196F,beta-lactamase_39_196,TEM-1,beta-lactamase_39,P62593,1.00797,NO,196,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-2.478,-4.226,1.748,,0.518,S,A,0.55,1.35,12.152,12.152,77.62,AHH,-1.839,0.0495842,0.00512144,1.00797 beta-lactamase_625_F149C,beta-lactamase_625_149,TEM-1,beta-lactamase_625,P62593,1.00797,NO,149,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.299,-4.94,3.641,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.213352,0.00418462,1.00797 beta-lactamase_156_S122D,beta-lactamase_156_122,TEM-1,beta-lactamase_156,P62593,1.00798,NO,122,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.406,-2.549,0.143,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.111618,0.00497825,1.00798 beta-lactamase_156_T147R,beta-lactamase_156_147,TEM-1,beta-lactamase_156,P62593,1.00798,NO,147,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.149,-3.809,2.66,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.111618,0.00226017,1.00798 beta-lactamase_2500_L196F,beta-lactamase_2500_196,TEM-1,beta-lactamase_2500,P62593,1.00798,NO,196,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-2.478,-4.226,1.748,,0.518,S,A,0.55,1.35,7.897,,77.62,AHH,-1.839,0.361275,0.00512144,1.00798 beta-lactamase_39_V82I,beta-lactamase_39_82,TEM-1,beta-lactamase_39,P62593,1.00798,NO,82,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.325,-2.197,0.872,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.0495842,0.00397046,1.00798 beta-lactamase_K109A,beta-lactamase_109,TEM-1,beta-lactamase,P62593,1.00798,NO,109,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.734,-3.283,1.549,6.05842,0.787,G,A,1.82,2.21,21.623,21.623,72.73,ABB,-1.63333,0.221079,0.00462493,1.00798 beta-lactamase_156_I171Y,beta-lactamase_156_171,TEM-1,beta-lactamase_156,P62593,1.00799,NO,171,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-2.431,-4.204,1.773,,0.361,,B,0.48,0.53,3.869,,77.62,HHO,-1.55533,0.111618,0.00623355,1.00799 beta-lactamase_39_L79V,beta-lactamase_39_79,TEM-1,beta-lactamase_39,P62593,1.00799,NO,79,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.842,-2.879,2.037,,0.007,H,A,0.55,-0.16,0.823,,50.35,HHP,-1.44333,0.0495842,0.000947397,1.00799 beta-lactamase_A148T,beta-lactamase_148,TEM-1,beta-lactamase,P62593,1.00799,NO,148,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.757,-2.508,0.751,5.28111,0.379,H,A,0.52,-0.55,2.117,,72.73,PHH,-1.40167,0.221079,0.00547053,1.00799 beta-lactamase_0_L188Q,beta-lactamase_0_188,TEM-1,beta-lactamase_0,P62593,1.008,NO,188,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.166,-4.055,2.889,,,H,A,0.55,-0.3,2.739,,60.14,PHB,-1.47033,0.0500837,0.00295687,1.008 beta-lactamase_39_S221F,beta-lactamase_39_221,TEM-1,beta-lactamase_39,P62593,1.008,NO,221,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.754,-4.221,2.467,,0.624,H,A,0.27,-0.2,2.69,,74.48,BPH,-1.59967,0.0495842,0.0046094,1.008 beta-lactamase_625_R59H,beta-lactamase_625_59,TEM-1,beta-lactamase_625,P62593,1.008,NO,59,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.345,-4.424,3.079,,0.329,S,L,1.2,-0.09,2.995,,73.08,HBO,-2.24267,0.213352,0.00318082,1.008 beta-lactamase_39_A124L,beta-lactamase_39_124,TEM-1,beta-lactamase_39,P62593,1.00801,NO,124,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.181,-3.172,1.991,,,H,A,0.46,-0.9,1.367,,64.34,HHH,-1.152,0.0495842,0.00481399,1.00801 beta-lactamase_39_Q37F,beta-lactamase_39_37,TEM-1,beta-lactamase_39,P62593,1.00801,NO,37,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.134,-4.314,2.18,,0.613,H,A,0.64,1.98,22.282,22.282,73.08,APH,-2.06967,0.0495842,0.00425833,1.00801 beta-lactamase_39_R275S,beta-lactamase_39_275,TEM-1,beta-lactamase_39,P62593,1.00801,NO,275,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.0495842,0.0141984,1.00801 beta-lactamase_625_T112S,beta-lactamase_625_112,TEM-1,beta-lactamase_625,P62593,1.00801,NO,112,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.186,-2.762,0.576,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.213352,0.00531334,1.00801 Pab1_Q194K,Pab1_194,Pab1,Pab1,P04147,1.00801,NO,194,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.179,-3.199,1.02,,,,,,,,,,OPA,-1.59767,0.175299,0.0016145,1.00801 PSD95pdz3_K380V,PSD95pdz3_380,PSD95pdz3,PSD95pdz3,P31016,1.00801,NO,380,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.416,-3.21,1.794,5.87979,,,,,19.6722,,,,HBP,-1.391,0.0758425,0.000281399,1.00801 beta-lactamase_156_G243S,beta-lactamase_156_243,TEM-1,beta-lactamase_156,P62593,1.00802,NO,243,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.532,,,,,E,B,0.77,-1.24,2.866,,50,BOH,-1.46867,0.111618,0.00464034,1.00802 beta-lactamase_625_A133G,beta-lactamase_625_133,TEM-1,beta-lactamase_625,P62593,1.00802,NO,133,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.186,-1.519,0.333,,,H,A,0.46,-0.86,0.373,,67.83,HHP,-0.988333,0.213352,0.00468022,1.00802 beta-lactamase_A266C,beta-lactamase_266,TEM-1,beta-lactamase,P62593,1.00802,NO,266,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.369,-3.203,1.834,5.02057,0.175,S,B,0.52,0.07,1.832,,64.34,PHP,-2.08567,0.221079,0.0140785,1.00802 kka2_1:4_L53P,kka2_1:4_53,Kka2,kka2_1:4,P00552,1.00802,NO,53,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-2.681,-2.005,-0.676,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.168804,0.00671168,1.00802 beta-lactamase_0_I93S,beta-lactamase_0_93,TEM-1,beta-lactamase_0,P62593,1.00803,NO,93,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.401,-3.663,2.262,,0.128,E,B,0.48,0.44,1.266,,67.83,BHB,-1.873,0.0500837,0.00527066,1.00803 beta-lactamase_156_S283G,beta-lactamase_156_283,TEM-1,beta-lactamase_156,P62593,1.00803,NO,283,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.111618,0.0429138,1.00803 beta-lactamase_625_P105M,beta-lactamase_625_105,TEM-1,beta-lactamase_625,P62593,1.00803,NO,105,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.813,-4.702,3.889,,0.226,T,A,0.52,0.8,1.154,,63.29,POH,-1.01533,0.213352,0.0011981,1.00803 beta-lactamase_625_T186R,beta-lactamase_625_186,TEM-1,beta-lactamase_625,P62593,1.00803,NO,186,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.522,-2.819,0.297,,0.396,H,A,0.22,-0.28,0.515,,77.62,HPP,-1.77633,0.213352,0.00485034,1.00803 WW_domain_D194Y,WW_domain_194,Yap65,WW_domain,P46937,1.00803,NO,194,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.536,-4.151,2.615,5.95614,,,,,,1.948,,74.4,HAP,-1.78933,0.153962,0.00483742,1.00803 beta-lactamase_0_P250L,beta-lactamase_0_250,TEM-1,beta-lactamase_0,P62593,1.00804,NO,250,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.0500837,0.00550899,1.00804 beta-lactamase_2500_Q267E,beta-lactamase_2500_267,TEM-1,beta-lactamase_2500,P62593,1.00804,NO,267,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.361275,0.0102128,1.00804 beta-lactamase_625_I54R,beta-lactamase_625_54,TEM-1,beta-lactamase_625,P62593,1.00804,NO,54,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-2.838,-2.365,-0.473,,0.669,E,B,0.48,-0.14,3.946,,73.78,BHH,-2.337,0.213352,0.00403589,1.00804 beta-lactamase_625_V72I,beta-lactamase_625_72,TEM-1,beta-lactamase_625,P62593,1.00804,NO,72,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.658,-3.311,1.653,,,H,A,0.44,-1.03,0.981,,65.73,BHH,-1.32167,0.213352,0.00501194,1.00804 beta-lactamase_156_K144W,beta-lactamase_156_144,TEM-1,beta-lactamase_156,P62593,1.00805,NO,144,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-2.388,-5.522,3.134,,0.863,H,A,2.34,1.27,2.073,,77.62,OBA,-1.904,0.111618,0.00481141,1.00805 beta-lactamase_39_Q267P,beta-lactamase_39_267,TEM-1,beta-lactamase_39,P62593,1.00805,NO,267,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.0495842,0.0102128,1.00805 beta-lactamase_A133A,beta-lactamase_133,TEM-1,beta-lactamase,P62593,1.00805,NO,133,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.186,-1.186,,4.86423,,H,A,0.55,-0.86,2.649,,67.83,HHP,-0.988333,0.221079,0.00468022,1.00805 beta-lactamase_156_A183K,beta-lactamase_156_183,TEM-1,beta-lactamase_156,P62593,1.00806,NO,183,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.231,-3.508,2.277,,0.155,H,A,0.46,-0.91,23.859,23.859,77.62,HHH,-1.53367,0.111618,0.00296631,1.00806 Ubiquitin_D52M,Ubiquitin_52,Uba1,Ubiquitin,P0CG48,1.00806,NO,52,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.43,-4.753,3.323,4.75143,0.421,T,A,,0.79,,,,AAO,-1.50267,0.205827,0.000806517,1.00806 Ubiquitin_D52N,Ubiquitin_52,Uba1,Ubiquitin,P0CG48,1.00806,NO,52,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.43,-2.219,0.789,4.75143,0.421,T,A,,0.79,,,,AAO,-1.50267,0.205827,0.000806517,1.00806 Ubiquitin_D52S,Ubiquitin_52,Uba1,Ubiquitin,P0CG48,1.00806,NO,52,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.43,-2.591,1.161,4.75143,0.421,T,A,,0.79,,,,AAO,-1.50267,0.205827,0.000806517,1.00806 Ubiquitin_D52V,Ubiquitin_52,Uba1,Ubiquitin,P0CG48,1.00806,NO,52,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.43,-3.565,2.135,4.75143,0.421,T,A,,0.79,,,,AAO,-1.50267,0.205827,0.000806517,1.00806 Ubiquitin_E16K,Ubiquitin_16,Uba1,Ubiquitin,P0CG48,1.00806,NO,16,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.545,-2.135,0.59,5.07465,0.567,E,B,,0.59,,,,HAH,-1.31367,0.205827,0.000786769,1.00806 Ubiquitin_E18A,Ubiquitin_18,Uba1,Ubiquitin,P0CG48,1.00806,NO,18,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.696,-2.672,0.976,5.04795,0.545,,B,,0.03,,,,HAO,-1.78733,0.205827,0.000623342,1.00806 Ubiquitin_E18D,Ubiquitin_18,Uba1,Ubiquitin,P0CG48,1.00806,NO,18,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.696,-2.338,0.642,5.04795,0.545,,B,,0.03,,,,HAO,-1.78733,0.205827,0.000623342,1.00806 Ubiquitin_E18H,Ubiquitin_18,Uba1,Ubiquitin,P0CG48,1.00806,NO,18,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.696,-3.224,1.528,5.04795,0.545,,B,,0.03,,,,HAO,-1.78733,0.205827,0.000623342,1.00806 Ubiquitin_E18I,Ubiquitin_18,Uba1,Ubiquitin,P0CG48,1.00806,NO,18,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.696,-2.992,1.296,5.04795,0.545,,B,,0.03,,,,HAO,-1.78733,0.205827,0.000623342,1.00806 Ubiquitin_E18K,Ubiquitin_18,Uba1,Ubiquitin,P0CG48,1.00806,NO,18,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.696,-2.784,1.088,5.04795,0.545,,B,,0.03,,,,HAO,-1.78733,0.205827,0.000623342,1.00806 Ubiquitin_E18L,Ubiquitin_18,Uba1,Ubiquitin,P0CG48,1.00806,NO,18,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.696,-3.405,1.709,5.04795,0.545,,B,,0.03,,,,HAO,-1.78733,0.205827,0.000623342,1.00806 Ubiquitin_E18M,Ubiquitin_18,Uba1,Ubiquitin,P0CG48,1.00806,NO,18,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.696,-3.311,1.615,5.04795,0.545,,B,,0.03,,,,HAO,-1.78733,0.205827,0.000623342,1.00806 Ubiquitin_E18N,Ubiquitin_18,Uba1,Ubiquitin,P0CG48,1.00806,NO,18,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.696,-2.653,0.957,5.04795,0.545,,B,,0.03,,,,HAO,-1.78733,0.205827,0.000623342,1.00806 Ubiquitin_E18Q,Ubiquitin_18,Uba1,Ubiquitin,P0CG48,1.00806,NO,18,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.696,-2.959,1.263,5.04795,0.545,,B,,0.03,,,,HAO,-1.78733,0.205827,0.000623342,1.00806 Ubiquitin_E18S,Ubiquitin_18,Uba1,Ubiquitin,P0CG48,1.00806,NO,18,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.696,-2.767,1.071,5.04795,0.545,,B,,0.03,,,,HAO,-1.78733,0.205827,0.000623342,1.00806 Ubiquitin_E18T,Ubiquitin_18,Uba1,Ubiquitin,P0CG48,1.00806,NO,18,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.696,-3.521,1.825,5.04795,0.545,,B,,0.03,,,,HAO,-1.78733,0.205827,0.000623342,1.00806 Ubiquitin_E18V,Ubiquitin_18,Uba1,Ubiquitin,P0CG48,1.00806,NO,18,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.696,-2.614,0.918,5.04795,0.545,,B,,0.03,,,,HAO,-1.78733,0.205827,0.000623342,1.00806 Ubiquitin_E64A,Ubiquitin_64,Uba1,Ubiquitin,P0CG48,1.00806,NO,64,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.763,-2.711,0.948,5.084,0.54,T,l,,0.79,,,,BAP,-1.64433,0.205827,0.000817406,1.00806 Ubiquitin_G35G,Ubiquitin_35,Uba1,Ubiquitin,P0CG48,1.00806,NO,35,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.171,-1.171,0,4.96213,0.713,,L,,0.2,,,,AOH,-1.314,0.205827,0.000648878,1.00806 Ubiquitin_G53G,Ubiquitin_53,Uba1,Ubiquitin,P0CG48,1.00806,NO,53,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.544,-1.544,0,5.32628,0.805,T,A,,-0.23,,,,AOB,-1.67033,0.205827,0.000662865,1.00806 Ubiquitin_I13M,Ubiquitin_13,Uba1,Ubiquitin,P0CG48,1.00806,NO,13,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.554,-3.031,1.477,5.19411,0.038,E,B,,-0.2,,,,PHP,-1.48,0.205827,0.000716423,1.00806 Ubiquitin_I3I,Ubiquitin_3,Uba1,Ubiquitin,P0CG48,1.00806,NO,3,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.402,-1.402,,4.80819,,E,B,,-0.78,,,,PHH,-1.54533,0.205827,0.000836911,1.00806 Ubiquitin_I61I,Ubiquitin_61,Uba1,Ubiquitin,P0CG48,1.00806,NO,61,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.514,-1.514,0,5.19922,0.038,,B,1,-0.76,1.953,,24.53,PHP,-1.70833,0.205827,0.000738268,1.00806 Ubiquitin_K29A,Ubiquitin_29,Uba1,Ubiquitin,P0CG48,1.00806,NO,29,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.471,-3.257,1.786,4.74832,0.355,H,A,,-0.06,,,,HBH,-1.52367,0.205827,0.000900239,1.00806 Ubiquitin_K29N,Ubiquitin_29,Uba1,Ubiquitin,P0CG48,1.00806,NO,29,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.471,-2.8,1.329,4.74832,0.355,H,A,,-0.06,,,,HBH,-1.52367,0.205827,0.000900239,1.00806 Ubiquitin_K29Y,Ubiquitin_29,Uba1,Ubiquitin,P0CG48,1.00806,NO,29,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.471,-4.144,2.673,4.74832,0.355,H,A,,-0.06,,,,HBH,-1.52367,0.205827,0.000900239,1.00806 Ubiquitin_L15L,Ubiquitin_15,Uba1,Ubiquitin,P0CG48,1.00806,NO,15,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.082,-1.082,,5.14718,0.029,E,B,1.16,-0.53,0.936,,38.69,PHA,-1.40833,0.205827,0.000519738,1.00806 Ubiquitin_L15V,Ubiquitin_15,Uba1,Ubiquitin,P0CG48,1.00806,NO,15,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.082,-2.043,0.961,5.14718,0.029,E,B,1.16,-0.53,0.936,,38.69,PHA,-1.40833,0.205827,0.000519738,1.00806 Ubiquitin_L67I,Ubiquitin_67,Uba1,Ubiquitin,P0CG48,1.00806,NO,67,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.435,-2.478,1.043,4.92156,,E,B,1.19,-1.02,6.371,6.371,30.8,PHB,-1.628,0.205827,0.000482727,1.00806 Ubiquitin_L67L,Ubiquitin_67,Uba1,Ubiquitin,P0CG48,1.00806,NO,67,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.435,-1.435,0,4.92156,,E,B,1.19,-1.02,6.371,6.371,30.8,PHB,-1.628,0.205827,0.000482727,1.00806 Ubiquitin_L67M,Ubiquitin_67,Uba1,Ubiquitin,P0CG48,1.00806,NO,67,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.435,-3.105,1.67,4.92156,,E,B,1.19,-1.02,6.371,6.371,30.8,PHB,-1.628,0.205827,0.000482727,1.00806 Ubiquitin_L8L,Ubiquitin_8,Uba1,Ubiquitin,P0CG48,1.00806,NO,8,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.723,-1.723,,5.28016,0.664,T,A,0.08,-0.34,0.664,,29.05,PHP,-1.51567,0.205827,0.000726165,1.00806 Ubiquitin_N60H,Ubiquitin_60,Uba1,Ubiquitin,P0CG48,1.00806,NO,60,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-1.775,-4.551,2.776,5.00332,0.775,T,L,,0.33,,,,HPH,-1.532,0.205827,0.000814061,1.00806 Ubiquitin_P37G,Ubiquitin_37,Uba1,Ubiquitin,P0CG48,1.00806,NO,37,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.275,-3.35,2.075,5.06918,0.323,,B,,-0.09,,,,HOO,-1.49,0.205827,0.000600764,1.00806 Ubiquitin_P37N,Ubiquitin_37,Uba1,Ubiquitin,P0CG48,1.00806,NO,37,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.275,-3.794,2.519,5.06918,0.323,,B,,-0.09,,,,HOO,-1.49,0.205827,0.000600764,1.00806 Ubiquitin_P37T,Ubiquitin_37,Uba1,Ubiquitin,P0CG48,1.00806,NO,37,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.275,-2.613,1.338,5.06918,0.323,,B,,-0.09,,,,HOO,-1.49,0.205827,0.000600764,1.00806 Ubiquitin_P38A,Ubiquitin_38,Uba1,Ubiquitin,P0CG48,1.00806,NO,38,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.718,-2.658,0.94,5.0146,0.316,G,A,,-0.52,,,,OOA,-1.595,0.205827,0.000781418,1.00806 Ubiquitin_P38C,Ubiquitin_38,Uba1,Ubiquitin,P0CG48,1.00806,NO,38,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.718,-3.317,1.599,5.0146,0.316,G,A,,-0.52,,,,OOA,-1.595,0.205827,0.000781418,1.00806 Ubiquitin_P38G,Ubiquitin_38,Uba1,Ubiquitin,P0CG48,1.00806,NO,38,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.718,-3.523,1.805,5.0146,0.316,G,A,,-0.52,,,,OOA,-1.595,0.205827,0.000781418,1.00806 Ubiquitin_Q31G,Ubiquitin_31,Uba1,Ubiquitin,P0CG48,1.00806,NO,31,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-1.678,-2.629,0.951,4.5004,0.464,H,A,,0.68,,,,HPA,-1.44467,0.205827,0.000724141,1.00806 Ubiquitin_Q31L,Ubiquitin_31,Uba1,Ubiquitin,P0CG48,1.00806,NO,31,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-1.678,-3.577,1.899,4.5004,0.464,H,A,,0.68,,,,HPA,-1.44467,0.205827,0.000724141,1.00806 Ubiquitin_Q41A,Ubiquitin_41,Uba1,Ubiquitin,P0CG48,1.00806,NO,41,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-1.329,-3.132,1.803,4.9201,0.017,E,B,0.12,-0.98,0.812,,30.07,PPB,-1.55067,0.205827,0.000521668,1.00806 Ubiquitin_Q41Q,Ubiquitin_41,Uba1,Ubiquitin,P0CG48,1.00806,NO,41,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-1.329,-1.329,0,4.9201,0.017,E,B,0.12,-0.98,0.812,,30.07,PPB,-1.55067,0.205827,0.000521668,1.00806 Ubiquitin_Q49Q,Ubiquitin_49,Uba1,Ubiquitin,P0CG48,1.00806,NO,49,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-1.941,-1.941,0,5.05026,0.403,E,B,,-0.59,,,,BPH,-1.49467,0.205827,0.000613067,1.00806 Ubiquitin_Q62E,Ubiquitin_62,Uba1,Ubiquitin,P0CG48,1.00806,NO,62,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-1.836,-2.366,0.53,5.33616,0.762,,B,,0.79,,,,HPB,-1.66167,0.205827,0.00068944,1.00806 Ubiquitin_Q62L,Ubiquitin_62,Uba1,Ubiquitin,P0CG48,1.00806,NO,62,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-1.836,-3.459,1.623,5.33616,0.762,,B,,0.79,,,,HPB,-1.66167,0.205827,0.00068944,1.00806 Ubiquitin_Q62S,Ubiquitin_62,Uba1,Ubiquitin,P0CG48,1.00806,NO,62,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-1.836,-2.782,0.946,5.33616,0.762,,B,,0.79,,,,HPB,-1.66167,0.205827,0.00068944,1.00806 Ubiquitin_R54I,Ubiquitin_54,Uba1,Ubiquitin,P0CG48,1.00806,NO,54,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.037,-3.833,1.796,5.14935,0.41,S,B,,0.87,,,,OBP,-1.72667,0.205827,0.000581095,1.00806 Ubiquitin_R54R,Ubiquitin_54,Uba1,Ubiquitin,P0CG48,1.00806,NO,54,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.037,-2.037,0,5.14935,0.41,S,B,,0.87,,,,OBP,-1.72667,0.205827,0.000581095,1.00806 Ubiquitin_R54V,Ubiquitin_54,Uba1,Ubiquitin,P0CG48,1.00806,NO,54,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.037,-2.896,0.859,5.14935,0.41,S,B,,0.87,,,,OBP,-1.72667,0.205827,0.000581095,1.00806 Ubiquitin_S20G,Ubiquitin_20,Uba1,Ubiquitin,P0CG48,1.00806,NO,20,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.539,-2.476,0.937,5.15339,0.672,T,A,,-0.6,,,,OPA,-1.69467,0.205827,0.000670478,1.00806 Ubiquitin_S20H,Ubiquitin_20,Uba1,Ubiquitin,P0CG48,1.00806,NO,20,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.539,-4.534,2.995,5.15339,0.672,T,A,,-0.6,,,,OPA,-1.69467,0.205827,0.000670478,1.00806 Ubiquitin_S20K,Ubiquitin_20,Uba1,Ubiquitin,P0CG48,1.00806,NO,20,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.539,-3.364,1.825,5.15339,0.672,T,A,,-0.6,,,,OPA,-1.69467,0.205827,0.000670478,1.00806 Ubiquitin_S20L,Ubiquitin_20,Uba1,Ubiquitin,P0CG48,1.00806,NO,20,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.539,-3.506,1.967,5.15339,0.672,T,A,,-0.6,,,,OPA,-1.69467,0.205827,0.000670478,1.00806 Ubiquitin_S20M,Ubiquitin_20,Uba1,Ubiquitin,P0CG48,1.00806,NO,20,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.539,-4.679,3.14,5.15339,0.672,T,A,,-0.6,,,,OPA,-1.69467,0.205827,0.000670478,1.00806 Ubiquitin_S20R,Ubiquitin_20,Uba1,Ubiquitin,P0CG48,1.00806,NO,20,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.539,-2.85,1.311,5.15339,0.672,T,A,,-0.6,,,,OPA,-1.69467,0.205827,0.000670478,1.00806 Ubiquitin_S20T,Ubiquitin_20,Uba1,Ubiquitin,P0CG48,1.00806,NO,20,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.539,-2.383,0.844,5.15339,0.672,T,A,,-0.6,,,,OPA,-1.69467,0.205827,0.000670478,1.00806 Ubiquitin_S57E,Ubiquitin_57,Uba1,Ubiquitin,P0CG48,1.00806,NO,57,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.879,-2.835,0.956,4.65125,0.456,G,A,,-0.42,,,,HPA,-1.60833,0.205827,0.000948086,1.00806 Ubiquitin_S57H,Ubiquitin_57,Uba1,Ubiquitin,P0CG48,1.00806,NO,57,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.879,-4.76,2.881,4.65125,0.456,G,A,,-0.42,,,,HPA,-1.60833,0.205827,0.000948086,1.00806 Ubiquitin_S57L,Ubiquitin_57,Uba1,Ubiquitin,P0CG48,1.00806,NO,57,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.879,-2.543,0.664,4.65125,0.456,G,A,,-0.42,,,,HPA,-1.60833,0.205827,0.000948086,1.00806 Ubiquitin_S57R,Ubiquitin_57,Uba1,Ubiquitin,P0CG48,1.00806,NO,57,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.879,-3.878,1.999,4.65125,0.456,G,A,,-0.42,,,,HPA,-1.60833,0.205827,0.000948086,1.00806 Ubiquitin_S57T,Ubiquitin_57,Uba1,Ubiquitin,P0CG48,1.00806,NO,57,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.879,-3.438,1.559,4.65125,0.456,G,A,,-0.42,,,,HPA,-1.60833,0.205827,0.000948086,1.00806 Ubiquitin_S65Q,Ubiquitin_65,Uba1,Ubiquitin,P0CG48,1.00806,NO,65,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.535,-3.89,2.355,4.99442,0.168,,b,0.25,-0.68,16.756,16.756,33.87,APP,-1.626,0.205827,0.000546776,1.00806 Ubiquitin_S65S,Ubiquitin_65,Uba1,Ubiquitin,P0CG48,1.00806,NO,65,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.535,-1.535,0,4.99442,0.168,,b,0.25,-0.68,16.756,16.756,33.87,APP,-1.626,0.205827,0.000546776,1.00806 Ubiquitin_S65T,Ubiquitin_65,Uba1,Ubiquitin,P0CG48,1.00806,NO,65,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.535,-2.704,1.169,4.99442,0.168,,b,0.25,-0.68,16.756,16.756,33.87,APP,-1.626,0.205827,0.000546776,1.00806 Ubiquitin_T55S,Ubiquitin_55,Uba1,Ubiquitin,P0CG48,1.00806,NO,55,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.599,-2.551,0.952,4.58329,0.173,B,B,,-0.68,,,,BPH,-1.65333,0.205827,0.000525703,1.00806 Ubiquitin_T66T,Ubiquitin_66,Uba1,Ubiquitin,P0CG48,1.00806,NO,66,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.58,-1.58,0,5.02702,0.46,E,B,0.8,-0.81,28.36,28.36,39.71,PPH,-1.51667,0.205827,0.000598414,1.00806 Ubiquitin_V17A,Ubiquitin_17,Uba1,Ubiquitin,P0CG48,1.00806,NO,17,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.314,-2.397,1.083,5.26282,0.017,,B,2.78,-0.77,3.239,,71.82,AHA,-1.51833,0.205827,0.000659638,1.00806 Ubiquitin_V17C,Ubiquitin_17,Uba1,Ubiquitin,P0CG48,1.00806,NO,17,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.314,-3.01,1.696,5.26282,0.017,,B,2.78,-0.77,3.239,,71.82,AHA,-1.51833,0.205827,0.000659638,1.00806 Ubiquitin_V17Y,Ubiquitin_17,Uba1,Ubiquitin,P0CG48,1.00806,NO,17,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.314,-3.954,2.64,5.26282,0.017,,B,2.78,-0.77,3.239,,71.82,AHA,-1.51833,0.205827,0.000659638,1.00806 Ubiquitin_Y59F,Ubiquitin_59,Uba1,Ubiquitin,P0CG48,1.00806,NO,59,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-1.307,-2.636,1.329,5.05599,0.072,G,A,0.43,-0.74,2.566,,24.53,AHP,-1.568,0.205827,0.000775084,1.00806 Ubiquitin_Y59H,Ubiquitin_59,Uba1,Ubiquitin,P0CG48,1.00806,NO,59,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-1.307,-2.938,1.631,5.05599,0.072,G,A,0.43,-0.74,2.566,,24.53,AHP,-1.568,0.205827,0.000775084,1.00806 beta-lactamase_39_L28T,beta-lactamase_39_28,TEM-1,beta-lactamase_39,P62593,1.00807,NO,28,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.579,-3.444,1.865,,0.277,H,A,0.55,-0.16,3.262,,93.01,PHH,-2.11333,0.0495842,0.00359321,1.00807 beta-lactamase_156_V157R,beta-lactamase_156_157,TEM-1,beta-lactamase_156,P62593,1.00808,NO,157,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.751,-3.07,1.319,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.111618,0.00506849,1.00808 beta-lactamase_625_R159T,beta-lactamase_625_159,TEM-1,beta-lactamase_625,P62593,1.00808,NO,159,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-0.94,-3.47,2.53,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.213352,0.00108472,1.00808 beta-lactamase_39_E166P,beta-lactamase_39_166,TEM-1,beta-lactamase_39,P62593,1.00809,NO,166,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.756,-3.897,2.141,,0.508,G,A,1.04,1.05,17.227,17.227,73.08,OAH,-1.42233,0.0495842,0.00512989,1.00809 beta-lactamase_39_L196S,beta-lactamase_39_196,TEM-1,beta-lactamase_39,P62593,1.00809,NO,196,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-2.478,-2.752,0.274,,0.518,S,A,0.55,1.35,12.152,12.152,77.62,AHH,-1.839,0.0495842,0.00512144,1.00809 beta-lactamase_625_E56G,beta-lactamase_625_56,TEM-1,beta-lactamase_625,P62593,1.00809,NO,56,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.043,-2.304,0.261,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.213352,0.00238534,1.00809 beta-lactamase_625_I54M,beta-lactamase_625_54,TEM-1,beta-lactamase_625,P62593,1.00809,NO,54,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-2.838,-3.13,0.292,,0.669,E,B,0.48,-0.14,3.946,,73.78,BHH,-2.337,0.213352,0.00403589,1.00809 PSD95pdz3_L360A,PSD95pdz3_360,PSD95pdz3,PSD95pdz3,P31016,1.00809,NO,360,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.431,-2.855,1.424,5.09284,,,,,14.2425,1.419,,86.88,HHP,-1.52667,0.0758425,0.000770471,1.00809 beta-lactamase_156_T263V,beta-lactamase_156_263,TEM-1,beta-lactamase_156,P62593,1.0081,NO,263,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.111618,0.0110582,1.0081 beta-lactamase_2500_L196R,beta-lactamase_2500_196,TEM-1,beta-lactamase_2500,P62593,1.0081,NO,196,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-2.478,-2.59,0.112,,0.518,S,A,0.55,1.35,7.897,,77.62,AHH,-1.839,0.361275,0.00512144,1.0081 beta-lactamase_625_M180H,beta-lactamase_625_180,TEM-1,beta-lactamase_625,P62593,1.00811,NO,180,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-2.795,-4.627,1.832,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.213352,0.00552048,1.00811 beta-lactamase_156_L248C,beta-lactamase_156_248,TEM-1,beta-lactamase_156,P62593,1.00812,NO,248,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.111618,0.00428493,1.00812 beta-lactamase_2500_A84K,beta-lactamase_2500_84,TEM-1,beta-lactamase_2500,P62593,1.00812,NO,84,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.651,-2.484,0.833,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.361275,0.00503822,1.00812 beta-lactamase_625_N173W,beta-lactamase_625_173,TEM-1,beta-lactamase_625,P62593,1.00812,NO,173,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-2.663,-5.303,2.64,,1.044,T,l,0.61,1.25,1.426,,77.62,OPA,-1.46633,0.213352,0.0033769,1.00812 beta-lactamase_2500_Q88N,beta-lactamase_2500_88,TEM-1,beta-lactamase_2500,P62593,1.00813,NO,88,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.086,-2.735,0.649,,0.807,,B,0.64,2.03,1.84,,77.62,APH,-1.53433,0.361275,0.00504167,1.00813 beta-lactamase_39_T198Y,beta-lactamase_39_198,TEM-1,beta-lactamase_39,P62593,1.00813,NO,198,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.168,-4.211,2.043,,0.489,,B,0.22,-0.13,3.614,,73.78,HPH,-1.98767,0.0495842,0.004311,1.00813 beta-lactamase_625_M67A,beta-lactamase_625_67,TEM-1,beta-lactamase_625,P62593,1.00813,NO,67,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-2.231,-2.183,-0.048,,0.006,G,P,0.55,-0.81,2.653,,65.03,HHP,-1.502,0.213352,0.00409753,1.00813 beta-lactamase_0_L205K,beta-lactamase_0_205,TEM-1,beta-lactamase_0,P62593,1.00814,NO,205,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.922,-3.736,2.814,,,H,A,0.55,-0.46,1.065,,42.31,PHH,-1.57767,0.0500837,0.00255802,1.00814 beta-lactamase_2500_T263I,beta-lactamase_2500_263,TEM-1,beta-lactamase_2500,P62593,1.00814,NO,263,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.361275,0.0110582,1.00814 beta-lactamase_39_F70W,beta-lactamase_39_70,TEM-1,beta-lactamase_39,P62593,1.00814,NO,70,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.169,-4.623,3.454,,,H,A,0.58,-1.34,1.14,,63.99,PHB,-0.980667,0.0495842,0.00193499,1.00814 beta-lactamase_39_V82R,beta-lactamase_39_82,TEM-1,beta-lactamase_39,P62593,1.00814,NO,82,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.325,-4.101,2.776,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.0495842,0.00397046,1.00814 beta-lactamase_625_L73P,beta-lactamase_625_73,TEM-1,beta-lactamase_625,P62593,1.00814,NO,73,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.507,-2.751,1.244,,,H,A,0.55,-0.64,2.933,,67.83,HHH,-1.487,0.213352,0.00488983,1.00814 beta-lactamase_625_P172A,beta-lactamase_625_172,TEM-1,beta-lactamase_625,P62593,1.00814,NO,172,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.998,-2.44,1.442,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.213352,0.00312594,1.00814 beta-lactamase_H24S,beta-lactamase_24,TEM-1,beta-lactamase,P62593,1.00814,NO,24,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-2.481,-1.903,-0.578,5.82767,,,,,,2.708,,93.01,HBO,-1.85167,0.221079,0.00238894,1.00814 beta-lactamase_625_L196R,beta-lactamase_625_196,TEM-1,beta-lactamase_625,P62593,1.00815,NO,196,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-2.478,-2.59,0.112,,0.518,S,A,0.55,1.35,12.152,12.152,77.62,AHH,-1.839,0.213352,0.00512144,1.00815 beta-lactamase_156_A247N,beta-lactamase_156_247,TEM-1,beta-lactamase_156,P62593,1.00816,NO,247,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.111618,0.00611275,1.00816 beta-lactamase_39_G216T,beta-lactamase_39_216,TEM-1,beta-lactamase_39,P62593,1.00817,NO,216,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.477,-3.599,2.122,,0.437,I,A,0.29,-0.58,0.834,,74.48,HOO,-1.68067,0.0495842,0.00639568,1.00817 beta-lactamase_39_N134K,beta-lactamase_39_134,TEM-1,beta-lactamase_39,P62593,1.00817,NO,134,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-0.879,-2.445,1.566,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.0495842,0.000644786,1.00817 beta-lactamase_625_R118T,beta-lactamase_625_118,TEM-1,beta-lactamase_625,P62593,1.00817,NO,118,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.413,-2.845,0.432,,0.457,H,A,1.2,1.39,2.144,,77.62,HBA,-1.785,0.213352,0.00538794,1.00817 beta-lactamase_Q86A,beta-lactamase_86,TEM-1,beta-lactamase,P62593,1.00817,NO,86,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.4,-2.601,0.201,5.39897,0.696,S,A,0.12,2.38,2.105,,77.62,OPA,-1.61067,0.221079,0.00450027,1.00817 beta-lactamase_156_D99R,beta-lactamase_156_99,TEM-1,beta-lactamase_156,P62593,1.00818,NO,99,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.191,-3.828,2.637,,0.402,G,A,0.75,0.36,3.529,,64.69,PAH,-1.794,0.111618,0.00305446,1.00818 beta-lactamase_156_H94W,beta-lactamase_156_94,TEM-1,beta-lactamase_156,P62593,1.00818,NO,94,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-2.5,-5.512,3.012,,0.776,,B,0.17,1.24,11.583,11.583,77.62,HBH,-1.872,0.111618,0.00389226,1.00818 beta-lactamase_625_G141S,beta-lactamase_625_141,TEM-1,beta-lactamase_625,P62593,1.00818,NO,141,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.828,-3.221,2.393,,0.575,T,l,0.29,-0.28,0.198,,64.69,HOO,-1.08933,0.213352,0.0012419,1.00818 beta-lactamase_156_T147M,beta-lactamase_156_147,TEM-1,beta-lactamase_156,P62593,1.00819,NO,147,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.149,-4.573,3.424,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.111618,0.00226017,1.00819 beta-lactamase_156_R239H,beta-lactamase_156_239,TEM-1,beta-lactamase_156,P62593,1.0082,NO,239,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.111618,0.00213852,1.0082 beta-lactamase_39_R220A,beta-lactamase_39_220,TEM-1,beta-lactamase_39,P62593,1.0082,NO,220,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-0.942,-2.357,1.415,,0.295,I,A,1.2,-0.76,1.596,,74.48,HBP,-1.33633,0.0495842,0.00232421,1.0082 beta-lactamase_2500_Q37M,beta-lactamase_2500_37,TEM-1,beta-lactamase_2500,P62593,1.00821,NO,37,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.134,-4.645,2.511,,0.613,H,A,0.64,1.98,1.318,,73.08,APH,-2.06967,0.361275,0.00425833,1.00821 kka2_1:2_R239T,kka2_1:2_239,Kka2,kka2_1:2,P00552,1.00821,NO,239,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.949,-3.616,0.667,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.295029,0.00835326,1.00821 beta-lactamase_156_A200V,beta-lactamase_156_200,TEM-1,beta-lactamase_156,P62593,1.00822,NO,200,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.878,-2.943,1.065,,0.757,H,A,0.46,-0.19,16.368,16.368,77.62,HHP,-2.001,0.111618,0.0060056,1.00822 beta-lactamase_156_L120M,beta-lactamase_156_120,TEM-1,beta-lactamase_156,P62593,1.00822,NO,120,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.044,-4.046,3.002,,,H,A,0.55,-1.13,7.813,,64.69,AHO,-1.13633,0.111618,0.00143563,1.00822 beta-lactamase_39_N152W,beta-lactamase_39_152,TEM-1,beta-lactamase_39,P62593,1.00822,NO,152,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-2.757,-5.472,2.715,,0.863,H,A,0.61,0.92,4.038,,77.62,BPH,-2.97,0.0495842,0.00471429,1.00822 beta-lactamase_0_N274C,beta-lactamase_0_274,TEM-1,beta-lactamase_0,P62593,1.00823,NO,274,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.0500837,0.0110418,1.00823 beta-lactamase_625_M127K,beta-lactamase_625_127,TEM-1,beta-lactamase_625,P62593,1.00823,NO,127,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-2.251,-3,0.749,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.213352,0.00437927,1.00823 beta-lactamase_0_F70W,beta-lactamase_0_70,TEM-1,beta-lactamase_0,P62593,1.00824,NO,70,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.169,-4.623,3.454,,,H,A,0.58,-1.34,2.153,,63.99,PHB,-0.980667,0.0500837,0.00193499,1.00824 beta-lactamase_156_I171S,beta-lactamase_156_171,TEM-1,beta-lactamase_156,P62593,1.00824,NO,171,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-2.431,-2.869,0.438,,0.361,,B,0.48,0.53,3.869,,77.62,HHO,-1.55533,0.111618,0.00623355,1.00824 beta-lactamase_156_T27L,beta-lactamase_156_27,TEM-1,beta-lactamase_156,P62593,1.00824,NO,27,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.905,-2.65,0.745,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.111618,0.00306559,1.00824 beta-lactamase_39_A215S,beta-lactamase_39_215,TEM-1,beta-lactamase_39,P62593,1.00824,NO,215,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.503,-2.232,0.729,,,,a,0.46,-0.93,0.494,,74.48,HHO,-1.42633,0.0495842,0.00544007,1.00824 beta-lactamase_156_T186V,beta-lactamase_156_186,TEM-1,beta-lactamase_156,P62593,1.00825,NO,186,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.522,-3.557,1.035,,0.396,H,A,0.22,-0.28,16.606,16.606,77.62,HPP,-1.77633,0.111618,0.00485034,1.00825 Pab1_I196V,Pab1_196,Pab1,Pab1,P04147,1.00825,NO,196,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.795,-1.248,-0.547,,,,,,,2.013,,80.59,AHH,-1.44667,0.175299,0.0016933,1.00825 WW_domain_A175Y,WW_domain_175,Yap65,WW_domain,P46937,1.00825,NO,175,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.631,-4.2,2.569,6.69537,,,,,,6.257,,83.93,OHO,-1.30033,0.153962,0.00326874,1.00825 beta-lactamase_156_T69I,beta-lactamase_156_69,TEM-1,beta-lactamase_156,P62593,1.00826,NO,69,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-0.973,-3.64,2.667,,,G,A,0.22,-1.24,4.194,,93.01,PPH,-1.01833,0.111618,0.00127498,1.00826 beta-lactamase_39_E61Y,beta-lactamase_39_61,TEM-1,beta-lactamase_39,P62593,1.00826,NO,61,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.115,-4.403,2.288,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.0495842,0.00440955,1.00826 beta-lactamase_39_R275F,beta-lactamase_39_275,TEM-1,beta-lactamase_39,P62593,1.00826,NO,275,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.0495842,0.0141984,1.00826 beta-lactamase_39_T112L,beta-lactamase_39_112,TEM-1,beta-lactamase_39,P62593,1.00826,NO,112,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.186,-3.575,1.389,,0.921,T,A,0.22,1.06,2.87,,73.78,HPA,-1.925,0.0495842,0.00531334,1.00826 beta-lactamase_625_L167M,beta-lactamase_625_167,TEM-1,beta-lactamase_625,P62593,1.00826,NO,167,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.138,-2.673,1.535,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.213352,0.00303566,1.00826 beta-lactamase_39_I140V,beta-lactamase_39_140,TEM-1,beta-lactamase_39,P62593,1.00827,NO,140,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.733,-1.662,-0.071,,0.128,H,A,0.48,0.41,1.16,,73.08,PHO,-1.48733,0.0495842,0.00597777,1.00827 beta-lactamase_39_D99H,beta-lactamase_39_99,TEM-1,beta-lactamase_39,P62593,1.00828,NO,99,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.191,-3.065,1.874,,0.402,G,A,0.75,0.36,0.374,,64.69,PAH,-1.794,0.0495842,0.00305446,1.00828 beta-lactamase_0_A182Q,beta-lactamase_0_182,TEM-1,beta-lactamase_0,P62593,1.0083,NO,182,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.777,-3.097,1.32,,0.136,H,A,0.46,-0.66,10.765,10.765,93.01,OHH,-1.27367,0.0500837,0.00559099,1.0083 beta-lactamase_39_L135I,beta-lactamase_39_135,TEM-1,beta-lactamase_39,P62593,1.0083,NO,135,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.002,-2.037,1.035,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.0495842,0.00244423,1.0083 beta-lactamase_625_A230G,beta-lactamase_625_230,TEM-1,beta-lactamase_625,P62593,1.0083,NO,230,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.154,-1.479,0.325,,0.01,E,B,0.46,-1.17,0.777,,50,HHA,-1.079,0.213352,0.00516841,1.0083 PSD95pdz3_S371C,PSD95pdz3_371,PSD95pdz3,PSD95pdz3,P31016,1.0083,NO,371,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.86,-4.414,2.554,5.19744,,,,,17.1117,3.854,,87.71,HPB,-1.598,0.0758425,0.000847873,1.0083 beta-lactamase_156_S221P,beta-lactamase_156_221,TEM-1,beta-lactamase_156,P62593,1.00832,NO,221,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.754,-3.814,2.06,,0.624,H,A,0.27,-0.2,17.729,17.729,74.48,BPH,-1.59967,0.111618,0.0046094,1.00832 beta-lactamase_39_Q86N,beta-lactamase_39_86,TEM-1,beta-lactamase_39,P62593,1.00832,NO,86,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.4,-3.754,1.354,,0.696,S,A,0.64,2.38,27.704,27.704,77.62,OPA,-1.61067,0.0495842,0.00450027,1.00832 Pab1_E161K,Pab1_161,Pab1,Pab1,P04147,1.00832,NO,161,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.474,-3.156,1.682,,0.663,T,a,,1.34,,,,AAP,-1.59067,0.175299,0.00276141,1.00832 beta-lactamase_625_K190F,beta-lactamase_625_190,TEM-1,beta-lactamase_625,P62593,1.00833,NO,190,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.994,-4.396,2.402,,0.371,H,A,2.34,0.16,29.753,29.753,77.62,BBH,-1.64167,0.213352,0.00574527,1.00833 beta-lactamase_39_A84R,beta-lactamase_39_84,TEM-1,beta-lactamase_39,P62593,1.00834,NO,84,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.651,-2.603,0.952,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.0495842,0.00503822,1.00834 beta-lactamase_625_Q37S,beta-lactamase_625_37,TEM-1,beta-lactamase_625,P62593,1.00834,NO,37,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.134,-2.839,0.705,,0.613,H,A,0.64,1.98,1.318,,73.08,APH,-2.06967,0.213352,0.00425833,1.00834 beta-lactamase_39_V157K,beta-lactamase_39_157,TEM-1,beta-lactamase_39,P62593,1.00835,NO,157,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.751,-2.698,0.947,,0.308,S,a,0.44,-0.75,10.364,10.364,69.58,BHP,-2.00767,0.0495842,0.00506849,1.00835 beta-lactamase_625_H151L,beta-lactamase_625_151,TEM-1,beta-lactamase_625,P62593,1.00835,NO,151,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-2.96,-3.494,0.534,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.213352,0.00216946,1.00835 beta-lactamase_625_K32M,beta-lactamase_625_32,TEM-1,beta-lactamase_625,P62593,1.00835,NO,32,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.984,-4.613,2.629,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.213352,0.00401283,1.00835 beta-lactamase_2500_S96E,beta-lactamase_2500_96,TEM-1,beta-lactamase_2500,P62593,1.00836,NO,96,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.27,-2.567,0.297,,0.368,,b,0.27,0.39,32.348,32.348,73.78,HPP,-2.019,0.361275,0.00551835,1.00836 beta-lactamase_39_S57K,beta-lactamase_39_57,TEM-1,beta-lactamase_39,P62593,1.00836,NO,57,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.918,-3.565,1.647,,0.352,E,B,0.27,-0.18,2.3,,72.73,APH,-2.29167,0.0495842,0.00492804,1.00836 beta-lactamase_625_T27I,beta-lactamase_625_27,TEM-1,beta-lactamase_625,P62593,1.00836,NO,27,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.905,-3.752,1.847,,0.007,H,A,0.22,-0.37,3.72,,93.01,APH,-1.97933,0.213352,0.00306559,1.00836 beta-lactamase_39_L223A,beta-lactamase_39_223,TEM-1,beta-lactamase_39,P62593,1.00837,NO,223,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.055,-3.102,2.047,,0.27,,B,0.55,0.09,1.511,,74.48,HHO,-1.35033,0.0495842,0.00372793,1.00837 beta-lactamase_39_M67E,beta-lactamase_39_67,TEM-1,beta-lactamase_39,P62593,1.00838,NO,67,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-2.231,-3.761,1.53,,0.006,G,P,0.55,-0.81,1.463,,65.03,HHP,-1.502,0.0495842,0.00409753,1.00838 beta-lactamase_625_K286D,beta-lactamase_625_286,TEM-1,beta-lactamase_625,P62593,1.00838,NO,286,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.213352,,1.00838 beta-lactamase_625_L55V,beta-lactamase_625_55,TEM-1,beta-lactamase_625,P62593,1.00838,NO,55,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.86,-2.346,0.486,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.213352,0.00403741,1.00838 beta-lactamase_2500_S122N,beta-lactamase_2500_122,TEM-1,beta-lactamase_2500,P62593,1.00839,NO,122,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.406,-3.042,0.636,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.361275,0.00497825,1.00839 beta-lactamase_39_A40H,beta-lactamase_39_40,TEM-1,beta-lactamase_39,P62593,1.00839,NO,40,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.402,-4.792,3.39,,0.155,S,B,0.46,0.21,0.783,,73.78,OHB,-1.40267,0.0495842,0.00490026,1.00839 beta-lactamase_39_G226S,beta-lactamase_39_226,TEM-1,beta-lactamase_39,P62593,1.00839,NO,226,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.461,-2.74,1.279,,0.701,T,l,0.29,-0.25,23.034,23.034,74.48,HOH,-1.42933,0.0495842,0.00665294,1.00839 beta-lactamase_625_L73A,beta-lactamase_625_73,TEM-1,beta-lactamase_625,P62593,1.00839,NO,73,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.507,-2.475,0.968,,,H,A,0.55,-0.64,2.933,,67.83,HHH,-1.487,0.213352,0.00488983,1.00839 beta-lactamase_A211H,beta-lactamase_211,TEM-1,beta-lactamase,P62593,1.00839,NO,211,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.896,-3.336,1.44,5.54662,0.369,T,A,0.52,-0.69,2.061,,77.62,AHA,-1.94633,0.221079,0.00648183,1.00839 beta-lactamase_A211N,beta-lactamase_211,TEM-1,beta-lactamase,P62593,1.00839,NO,211,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.896,-2.729,0.833,5.54662,0.369,T,A,0.52,-0.69,2.061,,77.62,AHA,-1.94633,0.221079,0.00648183,1.00839 beta-lactamase_A222N,beta-lactamase_222,TEM-1,beta-lactamase,P62593,1.00839,NO,222,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.103,-3.751,1.648,5.2262,0.233,H,A,0.47,-0.25,0.379,,77.62,PHH,-1.63733,0.221079,0.00466094,1.00839 beta-lactamase_A280V,beta-lactamase_280,TEM-1,beta-lactamase,P62593,1.00839,NO,280,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.708,-3.597,1.889,4.74932,0.379,H,A,0.52,-0.72,1.785,,68.18,OHP,-1.66433,0.221079,0.0530888,1.00839 beta-lactamase_A9M,beta-lactamase_9,TEM-1,beta-lactamase,P62593,1.00839,NO,9,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.147,-3.129,0.982,,,,,,,5.128,,72.73,HHH,-2.04267,0.221079,0.00247263,1.00839 beta-lactamase_C18T,beta-lactamase_18,TEM-1,beta-lactamase,P62593,1.00839,NO,18,C,T,CT,Special,Polar,5.07,5.6,0.53,149,121,119,-2,108.5,116.1,7.6,-2.26,-2.638,0.378,,,,,,,3.995,,93.01,HOH,-2.093,0.221079,0.002536,1.00839 beta-lactamase_D33N,beta-lactamase_33,TEM-1,beta-lactamase,P62593,1.00839,NO,33,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.321,-2.983,0.662,5.05203,0.366,H,A,0.23,0.33,2.032,,77.62,BAH,-2.12133,0.221079,0.00435556,1.00839 beta-lactamase_E26I,beta-lactamase_26,TEM-1,beta-lactamase,P62593,1.00839,NO,26,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.454,-3.782,1.328,,0.54,H,A,1.04,0.98,,,93.01,OAP,-1.96167,0.221079,0.00297948,1.00839 beta-lactamase_F70M,beta-lactamase_70,TEM-1,beta-lactamase,P62593,1.00839,NO,70,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.169,-3.002,1.833,5.42055,,H,A,1.1,-1.34,1.14,,63.99,PHB,-0.980667,0.221079,0.00193499,1.00839 beta-lactamase_H5H,beta-lactamase_5,TEM-1,beta-lactamase,P62593,1.00839,NO,5,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-2.698,-2.698,,,,,,,,1.865,,72.73,PBH,-2.36967,0.221079,0.00292712,1.00839 beta-lactamase_H94Y,beta-lactamase_94,TEM-1,beta-lactamase,P62593,1.00839,NO,94,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-2.5,-4.209,1.709,6.1507,0.776,,B,0.63,1.24,1.176,,77.62,HBH,-1.872,0.221079,0.00389226,1.00839 beta-lactamase_K213M,beta-lactamase_213,TEM-1,beta-lactamase,P62593,1.00839,NO,213,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.81,-4.653,2.843,5.63167,0.67,,A,1.59,0.29,3.924,,67.83,ABH,-1.57767,0.221079,0.00610411,1.00839 beta-lactamase_K284R,beta-lactamase_284,TEM-1,beta-lactamase,P62593,1.00839,NO,284,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.981,-2.253,0.272,6.30084,0.848,H,A,1.82,0.67,1.931,,77.62,HBB,-1.82133,0.221079,0.0686156,1.00839 beta-lactamase_K32A,beta-lactamase_32,TEM-1,beta-lactamase,P62593,1.00839,NO,32,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.984,-2.363,0.379,5.55842,0.563,H,A,1.82,0.34,1.754,,73.08,HBA,-2.04233,0.221079,0.00401283,1.00839 beta-lactamase_K32R,beta-lactamase_32,TEM-1,beta-lactamase,P62593,1.00839,NO,32,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.984,-2.38,0.396,5.55842,0.563,H,A,1.82,0.34,1.754,,73.08,HBA,-2.04233,0.221079,0.00401283,1.00839 beta-lactamase_L196C,beta-lactamase_196,TEM-1,beta-lactamase,P62593,1.00839,NO,196,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-2.478,-4.975,2.497,,0.518,S,A,0.55,1.35,,,77.62,AHH,-1.839,0.221079,0.00512144,1.00839 beta-lactamase_L19G,beta-lactamase_19,TEM-1,beta-lactamase,P62593,1.00839,NO,19,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.682,-3.626,1.944,,,,,,,4.261,,93.01,OHO,-1.894,0.221079,0.00215974,1.00839 beta-lactamase_N152A,beta-lactamase_152,TEM-1,beta-lactamase,P62593,1.00839,NO,152,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-2.757,-2.374,-0.383,5.98571,0.863,H,A,0.09,0.92,2.061,,77.62,BPH,-2.97,0.221079,0.00471429,1.00839 beta-lactamase_Q37M,beta-lactamase_37,TEM-1,beta-lactamase,P62593,1.00839,NO,37,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.134,-4.645,2.511,5.69153,0.613,H,A,0.12,1.98,1.318,,73.08,APH,-2.06967,0.221079,0.00425833,1.00839 beta-lactamase_Q4H,beta-lactamase_4,TEM-1,beta-lactamase,P62593,1.00839,NO,4,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,,-4.368,1.804,,,,,,,,,,HPB,,0.221079,0.00316562,1.00839 beta-lactamase_R273E,beta-lactamase_273,TEM-1,beta-lactamase,P62593,1.00839,NO,273,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.314,-2.209,-0.105,,0.564,H,A,1.2,1.57,,,73.78,ABP,-1.841,0.221079,0.0077952,1.00839 beta-lactamase_R7T,beta-lactamase_7,TEM-1,beta-lactamase,P62593,1.00839,NO,7,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.683,-3.443,1.76,,,,,,,2.44,,67.13,HBH,-1.96267,0.221079,0.00211375,1.00839 beta-lactamase_S2L,beta-lactamase_2,TEM-1,beta-lactamase,P62593,1.00839,NO,2,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.942,-2.845,0.903,,,,,,,2.36,,65.38,HPH,-2.02767,0.221079,0.00227352,1.00839 beta-lactamase_T112H,beta-lactamase_112,TEM-1,beta-lactamase,P62593,1.00839,NO,112,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.186,-4.734,2.548,6.47162,0.921,T,A,0.77,1.06,2.04,,73.78,HPA,-1.925,0.221079,0.00531334,1.00839 beta-lactamase_T193E,beta-lactamase_193,TEM-1,beta-lactamase,P62593,1.00839,NO,193,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.914,-3.756,1.842,5.67952,0.439,H,a,0.3,0.33,1.863,,63.99,HPO,-1.52133,0.221079,0.00482669,1.00839 beta-lactamase_V157N,beta-lactamase_157,TEM-1,beta-lactamase,P62593,1.00839,NO,157,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.751,-3.925,2.174,5.51733,0.308,S,a,0.96,-0.75,1.847,,69.58,BHP,-2.00767,0.221079,0.00506849,1.00839 beta-lactamase_39_G141W,beta-lactamase_39_141,TEM-1,beta-lactamase_39,P62593,1.0084,NO,141,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.828,-5.233,4.405,,0.575,T,l,0.29,-0.28,0.722,,64.69,HOO,-1.08933,0.0495842,0.0012419,1.0084 beta-lactamase_39_G281F,beta-lactamase_39_281,TEM-1,beta-lactamase_39,P62593,1.0084,NO,281,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.0495842,0.0406482,1.0084 beta-lactamase_39_P65M,beta-lactamase_39_65,TEM-1,beta-lactamase_39,P62593,1.0084,NO,65,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.894,-4.494,3.6,,0.098,E,B,0.52,-0.62,0.623,,40.56,HOH,-1.03233,0.0495842,0.00152776,1.0084 beta-lactamase_625_A84M,beta-lactamase_625_84,TEM-1,beta-lactamase_625,P62593,1.0084,NO,84,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.651,-4.707,3.056,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.213352,0.00503822,1.0084 kka2_1:2_E231W,kka2_1:2_231,Kka2,kka2_1:2,P00552,1.0084,NO,231,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.002,-5.602,3.6,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.295029,0.00732383,1.0084 kka2_1:8_T51K,kka2_1:8_51,Kka2,kka2_1:8,P00552,1.0084,NO,51,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.199,-3.076,0.877,,0.05,E,B,0.82,-0.05,5.399,,63.64,BPA,-1.76767,0.100394,0.00628861,1.0084 kka2_1:8_T51K,kka2_1:8_51,Kka2,kka2_1:8,P00552,1.0084,NO,51,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.199,-3.076,0.877,,0.05,E,B,0.82,-0.05,5.399,,63.64,BPA,-1.76767,0.100394,0.00628861,1.0084 beta-lactamase_156_E145S,beta-lactamase_156_145,TEM-1,beta-lactamase_156,P62593,1.00841,NO,145,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.357,-2.669,0.312,,0.545,H,A,1.04,0.79,3.661,,77.62,BAH,-2.069,0.111618,0.00553285,1.00841 beta-lactamase_625_M66A,beta-lactamase_625_66,TEM-1,beta-lactamase_625,P62593,1.00841,NO,66,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.362,-3.154,1.792,,0.013,,A,0.55,-0.7,1.659,,73.08,OHH,-1.49567,0.213352,0.00412876,1.00841 beta-lactamase_156_R189C,beta-lactamase_156_189,TEM-1,beta-lactamase_156,P62593,1.00842,NO,189,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.844,-5.229,3.385,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.111618,0.0050699,1.00842 beta-lactamase_2500_T112E,beta-lactamase_2500_112,TEM-1,beta-lactamase_2500,P62593,1.00842,NO,112,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.186,-2.494,0.308,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.361275,0.00531334,1.00842 beta-lactamase_39_N134V,beta-lactamase_39_134,TEM-1,beta-lactamase_39,P62593,1.00842,NO,134,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-0.879,-3.751,2.872,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.0495842,0.000644786,1.00842 beta-lactamase_39_W163H,beta-lactamase_39_163,TEM-1,beta-lactamase_39,P62593,1.00842,NO,163,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-1.843,-3.378,1.535,,0.467,,B,0.47,-0.5,15.095,15.095,63.99,BHA,-1.269,0.0495842,0.00418955,1.00842 beta-lactamase_625_D36V,beta-lactamase_625_36,TEM-1,beta-lactamase_625,P62593,1.00842,NO,36,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.732,-3.726,0.994,,0.555,H,A,0.75,1.17,2.26,,77.62,AAP,-1.91167,0.213352,0.00476483,1.00842 beta-lactamase_156_E175A,beta-lactamase_156_175,TEM-1,beta-lactamase_156,P62593,1.00843,NO,175,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.336,-2.1,-0.236,,0.551,,A,1.04,1.05,2.334,,77.62,AAB,-1.31233,0.111618,0.00482205,1.00843 beta-lactamase_156_L135S,beta-lactamase_156_135,TEM-1,beta-lactamase_156,P62593,1.00843,NO,135,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.002,-3.64,2.638,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.111618,0.00244423,1.00843 beta-lactamase_156_P217K,beta-lactamase_156_217,TEM-1,beta-lactamase_156,P62593,1.00843,NO,217,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-2.062,-2.687,0.625,,0.496,I,A,0.52,-0.33,2.303,,74.48,OOH,-1.64333,0.111618,0.00463211,1.00843 beta-lactamase_156_Y95W,beta-lactamase_156_95,TEM-1,beta-lactamase_156,P62593,1.00843,NO,95,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-1.715,-3.22,1.505,,0.122,,b,0.21,-0.37,2.341,,77.62,BHP,-2.16167,0.111618,0.00479449,1.00843 PSD95pdz3_G364A,PSD95pdz3_364,PSD95pdz3,PSD95pdz3,P31016,1.00843,NO,364,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.008,-2.534,1.526,5.53299,,,,,21.28,,,,POH,-1.33667,0.0758425,0.00050942,1.00843 beta-lactamase_156_P217H,beta-lactamase_156_217,TEM-1,beta-lactamase_156,P62593,1.00844,NO,217,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-2.062,-3.354,1.292,,0.496,I,A,0.52,-0.33,2.303,,74.48,OOH,-1.64333,0.111618,0.00463211,1.00844 beta-lactamase_156_R202T,beta-lactamase_156_202,TEM-1,beta-lactamase_156,P62593,1.00844,NO,202,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.292,-3.438,2.146,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.111618,0.00321899,1.00844 beta-lactamase_39_F64Y,beta-lactamase_39_64,TEM-1,beta-lactamase_39,P62593,1.00844,NO,64,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-0.841,-3.037,2.196,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.0495842,0.000947691,1.00844 beta-lactamase_39_N50T,beta-lactamase_39_50,TEM-1,beta-lactamase_39,P62593,1.00844,NO,50,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-2.979,-2.678,-0.301,,0.912,T,A,0.61,1.24,10.736,,77.62,HPP,-2.134,0.0495842,0.0047211,1.00844 beta-lactamase_625_T158F,beta-lactamase_625_158,TEM-1,beta-lactamase_625,P62593,1.00844,NO,158,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.116,-4.177,3.061,,0.036,,B,0.22,-0.85,3.771,,69.58,HPB,-1.269,0.213352,0.00341825,1.00844 Pab1_I196M,Pab1_196,Pab1,Pab1,P04147,1.00844,NO,196,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.795,-3.923,2.128,,,,,,,2.013,,80.59,AHH,-1.44667,0.175299,0.0016933,1.00844 beta-lactamase_156_D177N,beta-lactamase_156_177,TEM-1,beta-lactamase_156,P62593,1.00845,NO,177,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.967,-2.571,1.604,,0.006,T,L,0.75,-1.02,2.072,,64.69,BAP,-0.873667,0.111618,0.000864022,1.00845 beta-lactamase_156_P25G,beta-lactamase_156_25,TEM-1,beta-lactamase_156,P62593,1.00845,NO,25,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.526,-2.198,0.672,,0.624,H,A,0.52,0.14,1.079,,73.08,BOA,-2.15367,0.111618,0.00347571,1.00845 beta-lactamase_39_P60W,beta-lactamase_39_60,TEM-1,beta-lactamase_39,P62593,1.00845,NO,60,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-2.469,-5.456,2.987,,0.256,T,A,0.52,-0.56,21.37,21.37,77.62,BOA,-1.97633,0.0495842,0.00521318,1.00845 kka2_1:8_G164N,kka2_1:8_164,Kka2,kka2_1:8,P00552,1.00845,NO,164,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.869,-2.458,1.589,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.100394,0.00442091,1.00845 kka2_1:8_G164N,kka2_1:8_164,Kka2,kka2_1:8,P00552,1.00845,NO,164,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.869,-2.458,1.589,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.100394,0.00442091,1.00845 kka2_1:8_T187A,kka2_1:8_187,Kka2,kka2_1:8,P00552,1.00845,NO,187,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.273,-1.915,0.642,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.100394,0.00693073,1.00845 kka2_1:8_T187A,kka2_1:8_187,Kka2,kka2_1:8,P00552,1.00845,NO,187,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.273,-1.915,0.642,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.100394,0.00693073,1.00845 beta-lactamase_39_A183L,beta-lactamase_39_183,TEM-1,beta-lactamase_39,P62593,1.00846,NO,183,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.231,-3.283,2.052,,0.155,H,A,0.46,-0.91,1.237,,77.62,HHH,-1.53367,0.0495842,0.00296631,1.00846 beta-lactamase_39_Q37L,beta-lactamase_39_37,TEM-1,beta-lactamase_39,P62593,1.00846,NO,37,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.134,-2.893,0.759,,0.613,H,A,0.64,1.98,22.282,22.282,73.08,APH,-2.06967,0.0495842,0.00425833,1.00846 beta-lactamase_625_E195Q,beta-lactamase_625_195,TEM-1,beta-lactamase_625,P62593,1.00846,NO,195,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.186,-2.527,0.341,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.213352,0.00496565,1.00846 beta-lactamase_625_T186K,beta-lactamase_625_186,TEM-1,beta-lactamase_625,P62593,1.00846,NO,186,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.522,-2.678,0.156,,0.396,H,A,0.22,-0.28,0.515,,77.62,HPP,-1.77633,0.213352,0.00485034,1.00846 beta-lactamase_A222T,beta-lactamase_222,TEM-1,beta-lactamase,P62593,1.00846,NO,222,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.103,-2.805,0.702,5.2262,0.233,H,A,0.47,-0.25,0.379,,77.62,PHH,-1.63733,0.221079,0.00466094,1.00846 gb1_Y229F,gb1_229,gb1,gb1,P06654,1.00846,NO,229,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-1.282,-2.678,1.396,,,,,,,,,,PHB,-1.4915,0.177985,0.00366605,1.00846 beta-lactamase_156_N173W,beta-lactamase_156_173,TEM-1,beta-lactamase_156,P62593,1.00847,NO,173,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-2.663,-5.303,2.64,,1.044,T,l,0.61,1.25,3.718,,77.62,OPA,-1.46633,0.111618,0.0033769,1.00847 beta-lactamase_156_S80G,beta-lactamase_156_80,TEM-1,beta-lactamase_156,P62593,1.00847,NO,80,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.029,-3.327,1.298,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.111618,0.00565569,1.00847 beta-lactamase_625_P250D,beta-lactamase_625_250,TEM-1,beta-lactamase_625,P62593,1.00847,NO,250,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-2.335,-1.83,-0.505,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.213352,0.00550899,1.00847 beta-lactamase_625_S266N,beta-lactamase_625_266,TEM-1,beta-lactamase_625,P62593,1.00847,NO,266,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.213352,0.0140785,1.00847 beta-lactamase_625_Y262M,beta-lactamase_625_262,TEM-1,beta-lactamase_625,P62593,1.00847,NO,262,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.213352,0.00853516,1.00847 kka2_1:8_L152N,kka2_1:8_152,Kka2,kka2_1:8,P00552,1.00847,NO,152,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.521,-4.061,2.54,,0.547,.,A,0.55,1.36,1.442,,63.64,OHH,-1.162,0.100394,0.00674868,1.00847 kka2_1:8_L152N,kka2_1:8_152,Kka2,kka2_1:8,P00552,1.00847,NO,152,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.521,-4.061,2.54,,0.547,.,A,0.55,1.36,1.442,,63.64,OHH,-1.162,0.100394,0.00674868,1.00847 beta-lactamase_0_R176Q,beta-lactamase_0_176,TEM-1,beta-lactamase_0,P62593,1.00848,NO,176,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-0.863,-3.449,2.586,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.0500837,0.00105554,1.00848 beta-lactamase_156_P165G,beta-lactamase_156_165,TEM-1,beta-lactamase_156,P62593,1.00848,NO,165,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.373,-3.429,2.056,,0.203,T,A,0.52,-0.31,3.907,,73.78,AOA,-1.359,0.111618,0.00549538,1.00848 beta-lactamase_156_R41V,beta-lactamase_156_41,TEM-1,beta-lactamase_156,P62593,1.00848,NO,41,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-0.942,-3.751,2.809,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.111618,0.00123327,1.00848 beta-lactamase_39_E279C,beta-lactamase_39_279,TEM-1,beta-lactamase_39,P62593,1.00848,NO,279,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.0495842,0.0192826,1.00848 beta-lactamase_39_R202Q,beta-lactamase_39_202,TEM-1,beta-lactamase_39,P62593,1.00848,NO,202,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.292,-1.95,0.658,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.0495842,0.00321899,1.00848 beta-lactamase_39_T116L,beta-lactamase_39_116,TEM-1,beta-lactamase_39,P62593,1.00848,NO,116,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.28,-3.376,2.096,,0.115,E,B,0.22,-0.12,1.133,,67.48,HPH,-1.39967,0.0495842,0.00336175,1.00848 beta-lactamase_2500_L73I,beta-lactamase_2500_73,TEM-1,beta-lactamase_2500,P62593,1.00849,NO,73,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.507,-2.52,1.013,,,H,A,0.55,-0.64,2.178,,67.83,HHH,-1.487,0.361275,0.00488983,1.00849 Pab1_H134V,Pab1_134,Pab1,Pab1,P04147,1.0085,NO,134,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-1.542,-3.685,2.143,,,,,,,,,,HBO,-1.346,0.175299,0.00116356,1.0085 beta-lactamase_156_Q204I,beta-lactamase_156_204,TEM-1,beta-lactamase_156,P62593,1.00851,NO,204,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-1.382,-3.968,2.586,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.111618,0.00364106,1.00851 beta-lactamase_625_T27V,beta-lactamase_625_27,TEM-1,beta-lactamase_625,P62593,1.00851,NO,27,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.905,-3.409,1.504,,0.007,H,A,0.22,-0.37,3.72,,93.01,APH,-1.97933,0.213352,0.00306559,1.00851 beta-lactamase_156_I54M,beta-lactamase_156_54,TEM-1,beta-lactamase_156,P62593,1.00852,NO,54,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-2.838,-3.13,0.292,,0.669,E,B,0.48,-0.14,0.541,,73.78,BHH,-2.337,0.111618,0.00403589,1.00852 beta-lactamase_156_S80R,beta-lactamase_156_80,TEM-1,beta-lactamase_156,P62593,1.00852,NO,80,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.029,-3.076,1.047,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.111618,0.00565569,1.00852 beta-lactamase_39_L191W,beta-lactamase_39_191,TEM-1,beta-lactamase_39,P62593,1.00852,NO,191,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.087,-5.14,4.053,,,H,A,0.55,0.09,1.372,,63.29,BHH,-1.445,0.0495842,0.00263549,1.00852 beta-lactamase_39_S96G,beta-lactamase_39_96,TEM-1,beta-lactamase_39,P62593,1.00852,NO,96,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.27,-2.481,0.211,,0.368,,b,0.27,0.39,2.516,,73.78,HPP,-2.019,0.0495842,0.00551835,1.00852 beta-lactamase_D36E,beta-lactamase_36,TEM-1,beta-lactamase,P62593,1.00852,NO,36,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.732,-2.66,-0.072,5.39764,0.555,H,A,0.11,1.17,13.689,13.689,77.62,AAP,-1.91167,0.221079,0.00476483,1.00852 beta-lactamase_156_K30A,beta-lactamase_156_30,TEM-1,beta-lactamase_156,P62593,1.00853,NO,30,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-2.307,-2.101,-0.206,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.111618,0.00448593,1.00853 beta-lactamase_2500_P60M,beta-lactamase_2500_60,TEM-1,beta-lactamase_2500,P62593,1.00853,NO,60,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-2.469,-4.701,2.232,,0.256,T,A,0.52,-0.56,1.581,,77.62,BOA,-1.97633,0.361275,0.00521318,1.00853 beta-lactamase_156_S201T,beta-lactamase_156_201,TEM-1,beta-lactamase_156,P62593,1.00854,NO,201,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.183,-3.198,2.015,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.111618,0.00198815,1.00854 beta-lactamase_39_M66A,beta-lactamase_39_66,TEM-1,beta-lactamase_39,P62593,1.00854,NO,66,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.362,-3.154,1.792,,0.013,,A,0.55,-0.7,1.319,,73.08,OHH,-1.49567,0.0495842,0.00412876,1.00854 beta-lactamase_39_R59T,beta-lactamase_39_59,TEM-1,beta-lactamase_39,P62593,1.00854,NO,59,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.345,-3.487,2.142,,0.329,S,L,1.2,-0.09,1.806,,73.08,HBO,-2.24267,0.0495842,0.00318082,1.00854 kka2_1:4_L174V,kka2_1:4_174,Kka2,kka2_1:4,P00552,1.00854,NO,174,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.952,-2.256,1.304,,,H,A,0.55,-0.31,1.339,,51.89,BHB,-2.08533,0.168804,0.00438501,1.00854 beta-lactamase_156_D36S,beta-lactamase_156_36,TEM-1,beta-lactamase_156,P62593,1.00855,NO,36,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.732,-2.107,-0.625,,0.555,H,A,0.75,1.17,14.871,14.871,77.62,AAP,-1.91167,0.111618,0.00476483,1.00855 beta-lactamase_39_E166C,beta-lactamase_39_166,TEM-1,beta-lactamase_39,P62593,1.00855,NO,166,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.756,-5.069,3.313,,0.508,G,A,1.04,1.05,17.227,17.227,73.08,OAH,-1.42233,0.0495842,0.00512989,1.00855 beta-lactamase_39_L205T,beta-lactamase_39_205,TEM-1,beta-lactamase_39,P62593,1.00855,NO,205,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.922,-3.476,2.554,,,H,A,0.55,-0.46,0.846,,42.31,PHH,-1.57767,0.0495842,0.00255802,1.00855 beta-lactamase_625_I54W,beta-lactamase_625_54,TEM-1,beta-lactamase_625,P62593,1.00855,NO,54,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-2.838,-5.452,2.614,,0.669,E,B,0.48,-0.14,3.946,,73.78,BHH,-2.337,0.213352,0.00403589,1.00855 beta-lactamase_H24H,beta-lactamase_24,TEM-1,beta-lactamase,P62593,1.00855,NO,24,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-2.481,-2.481,,5.82767,,,,,,2.708,,93.01,HBO,-1.85167,0.221079,0.00238894,1.00855 beta-lactamase_156_N98K,beta-lactamase_156_98,TEM-1,beta-lactamase_156,P62593,1.00856,NO,98,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-2.973,-2.653,-0.32,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.111618,0.00505389,1.00856 beta-lactamase_2500_A211R,beta-lactamase_2500_211,TEM-1,beta-lactamase_2500,P62593,1.00856,NO,211,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.896,-3.077,1.181,,0.369,T,A,0.46,-0.69,2.061,,77.62,AHA,-1.94633,0.361275,0.00648183,1.00856 beta-lactamase_2500_E238R,beta-lactamase_2500_238,TEM-1,beta-lactamase_2500,P62593,1.00856,NO,238,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.002,-3.465,1.463,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.361275,0.00743256,1.00856 beta-lactamase_625_M127S,beta-lactamase_625_127,TEM-1,beta-lactamase_625,P62593,1.00856,NO,127,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-2.251,-3.644,1.393,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.213352,0.00437927,1.00856 beta-lactamase_I171R,beta-lactamase_171,TEM-1,beta-lactamase,P62593,1.00856,NO,171,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-2.431,-2.473,0.042,5.22771,0.361,,B,1,0.53,1.66,,77.62,HHO,-1.55533,0.221079,0.00623355,1.00856 kka2_1:1_D5V,kka2_1:1_5,Kka2,kka2_1:1,P00552,1.00856,NO,5,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.306,-3.484,2.178,,,,,,,0.895,,71.59,PAO,-1.784,0.520039,0.00222864,1.00856 PSD95pdz3_G364D,PSD95pdz3_364,PSD95pdz3,PSD95pdz3,P31016,1.00856,NO,364,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.008,-3.15,2.142,5.53299,,,,,21.28,,,,POH,-1.33667,0.0758425,0.00050942,1.00856 beta-lactamase_156_L150C,beta-lactamase_156_150,TEM-1,beta-lactamase_156,P62593,1.00857,NO,150,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.326,-4.732,3.406,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.111618,0.00463171,1.00857 beta-lactamase_156_M66L,beta-lactamase_156_66,TEM-1,beta-lactamase_156,P62593,1.00857,NO,66,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.362,-1.674,0.312,,0.013,,A,0.55,-0.7,1.94,,73.08,OHH,-1.49567,0.111618,0.00412876,1.00857 beta-lactamase_156_T126C,beta-lactamase_156_126,TEM-1,beta-lactamase_156,P62593,1.00857,NO,126,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.122,-4.816,3.694,,0.05,H,A,0.22,-0.05,1.14,,44.41,HPH,-1.60467,0.111618,0.00244552,1.00857 beta-lactamase_2500_E238N,beta-lactamase_2500_238,TEM-1,beta-lactamase_2500,P62593,1.00857,NO,238,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.361275,0.00743256,1.00857 beta-lactamase_625_N152Q,beta-lactamase_625_152,TEM-1,beta-lactamase_625,P62593,1.00857,NO,152,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-2.757,-2.534,-0.223,,0.863,H,A,0.61,0.92,2.061,,77.62,BPH,-2.97,0.213352,0.00471429,1.00857 beta-lactamase_2500_R189H,beta-lactamase_2500_189,TEM-1,beta-lactamase_2500,P62593,1.00858,NO,189,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.844,-2.544,0.7,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.361275,0.0050699,1.00858 beta-lactamase_156_A222H,beta-lactamase_156_222,TEM-1,beta-lactamase_156,P62593,1.00859,NO,222,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.103,-2.705,0.602,,0.233,H,A,0.46,-0.25,2.461,,77.62,PHH,-1.63733,0.111618,0.00466094,1.00859 beta-lactamase_156_P165V,beta-lactamase_156_165,TEM-1,beta-lactamase_156,P62593,1.00859,NO,165,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.373,-3.333,1.96,,0.203,T,A,0.52,-0.31,3.907,,73.78,AOA,-1.359,0.111618,0.00549538,1.00859 beta-lactamase_Q97L,beta-lactamase_97,TEM-1,beta-lactamase,P62593,1.00859,NO,97,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.072,-3.528,1.456,6.30204,0.823,G,A,1.1,2.42,1.157,,77.62,PPP,-2.43833,0.221079,0.0045116,1.00859 kka2_1:8_V36A,kka2_1:8_36,Kka2,kka2_1:8,P00552,1.00859,NO,36,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-0.898,-2.963,2.065,,0.292,E,B,1.48,0.21,0.938,,52.27,HHH,-1.484,0.100394,0.00245633,1.00859 kka2_1:8_V36A,kka2_1:8_36,Kka2,kka2_1:8,P00552,1.00859,NO,36,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-0.898,-2.963,2.065,,0.292,E,B,1.48,0.21,0.938,,52.27,HHH,-1.484,0.100394,0.00245633,1.00859 beta-lactamase_0_E210L,beta-lactamase_0_210,TEM-1,beta-lactamase_0,P62593,1.0086,NO,210,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.319,-2.05,-0.269,,0.476,H,A,1.04,0.75,3.618,,77.62,HAH,-1.88567,0.0500837,0.00663582,1.0086 beta-lactamase_156_A182R,beta-lactamase_156_182,TEM-1,beta-lactamase_156,P62593,1.0086,NO,182,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.777,-2.31,0.533,,0.136,H,A,0.46,-0.66,16.784,16.784,93.01,OHH,-1.27367,0.111618,0.00559099,1.0086 beta-lactamase_625_L89A,beta-lactamase_625_89,TEM-1,beta-lactamase_625,P62593,1.0086,NO,89,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.096,-2.465,1.369,,0.168,T,A,0.55,0.63,1.599,,64.34,PHO,-1.75767,0.213352,0.00207068,1.0086 kka2_1:2_Q136C,kka2_1:2_136,Kka2,kka2_1:2,P00552,1.0086,NO,136,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-3.021,-3.362,0.341,,0.331,,b,0.4,0.96,2.726,,92.05,BPH,-2.16933,0.295029,0.00624149,1.0086 beta-lactamase_39_A77C,beta-lactamase_39_77,TEM-1,beta-lactamase_39,P62593,1.00861,NO,77,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.234,-4.708,3.474,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.0495842,0.00282362,1.00861 beta-lactamase_625_R92Q,beta-lactamase_625_92,TEM-1,beta-lactamase_625,P62593,1.00861,NO,92,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.718,-3.029,1.311,,0.479,E,B,1.2,1.36,3.069,,65.38,BBH,-1.50367,0.213352,0.00429626,1.00861 beta-lactamase_156_M67E,beta-lactamase_156_67,TEM-1,beta-lactamase_156,P62593,1.00862,NO,67,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-2.231,-3.761,1.53,,0.006,G,P,0.55,-0.81,1.463,,65.03,HHP,-1.502,0.111618,0.00409753,1.00862 beta-lactamase_39_K109S,beta-lactamase_39_109,TEM-1,beta-lactamase_39,P62593,1.00862,NO,109,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.734,-2.861,1.127,,0.787,G,A,2.34,2.21,7.243,,72.73,ABB,-1.63333,0.0495842,0.00462493,1.00862 beta-lactamase_39_T186P,beta-lactamase_39_186,TEM-1,beta-lactamase_39,P62593,1.00862,NO,186,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.522,-3.945,1.423,,0.396,H,A,0.22,-0.28,0.515,,77.62,HPP,-1.77633,0.0495842,0.00485034,1.00862 gb1_I232V,gb1_232,gb1,gb1,P06654,1.00862,NO,232,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-2.175,-1.804,-0.371,,,,,,,0.766,,44.87,HHH,-2.152,0.177985,0.00580459,1.00862 gb1_K236I,gb1_236,gb1,gb1,P06654,1.00862,NO,236,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-2.119,-3.78,1.661,,,,,,,1.083,,45.54,OBP,-1.758,0.177985,0.00255408,1.00862 beta-lactamase_156_S283R,beta-lactamase_156_283,TEM-1,beta-lactamase_156,P62593,1.00863,NO,283,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.111618,0.0429138,1.00863 beta-lactamase_39_E166N,beta-lactamase_39_166,TEM-1,beta-lactamase_39,P62593,1.00863,NO,166,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.756,-3.709,1.953,,0.508,G,A,1.04,1.05,17.227,17.227,73.08,OAH,-1.42233,0.0495842,0.00512989,1.00863 beta-lactamase_39_L137N,beta-lactamase_39_137,TEM-1,beta-lactamase_39,P62593,1.00863,NO,137,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.03,-4.152,3.122,,,H,A,0.55,-0.38,0.674,,42.31,HHP,-1.58933,0.0495842,0.00278599,1.00863 beta-lactamase_156_E87C,beta-lactamase_156_87,TEM-1,beta-lactamase_156,P62593,1.00864,NO,87,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.421,-5.162,3.741,,0.048,,B,1.04,0.92,1.754,,64.69,PAP,-1.969,0.111618,0.00337888,1.00864 kka2_1:8_Q100K,kka2_1:8_100,Kka2,kka2_1:8,P00552,1.00864,NO,100,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.77,-3.068,0.298,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.100394,0.0066405,1.00864 kka2_1:8_Q100K,kka2_1:8_100,Kka2,kka2_1:8,P00552,1.00864,NO,100,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.77,-3.068,0.298,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.100394,0.0066405,1.00864 beta-lactamase_0_R63T,beta-lactamase_0_63,TEM-1,beta-lactamase_0,P62593,1.00865,NO,63,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-0.943,-3.447,2.504,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.0500837,0.00126938,1.00865 beta-lactamase_156_A278H,beta-lactamase_156_278,TEM-1,beta-lactamase_156,P62593,1.00865,NO,278,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.111618,0.0310297,1.00865 beta-lactamase_156_I45L,beta-lactamase_156_45,TEM-1,beta-lactamase_156,P62593,1.00865,NO,45,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-2.421,-2.39,-0.031,,,E,B,0.48,-0.3,2.256,,77.62,HHA,-2.30267,0.111618,0.00452842,1.00865 beta-lactamase_39_P143F,beta-lactamase_39_143,TEM-1,beta-lactamase_39,P62593,1.00865,NO,143,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.967,-4.308,3.341,,0.075,H,A,0.52,-0.37,0.976,,66.78,OOB,-1.354,0.0495842,0.00114551,1.00865 beta-lactamase_625_L150S,beta-lactamase_625_150,TEM-1,beta-lactamase_625,P62593,1.00865,NO,150,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.326,-3.477,2.151,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.213352,0.00463171,1.00865 beta-lactamase_156_M66Q,beta-lactamase_156_66,TEM-1,beta-lactamase_156,P62593,1.00866,NO,66,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.362,-3.949,2.587,,0.013,,A,0.55,-0.7,1.94,,73.08,OHH,-1.49567,0.111618,0.00412876,1.00866 beta-lactamase_625_R242K,beta-lactamase_625_242,TEM-1,beta-lactamase_625,P62593,1.00866,NO,242,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.213352,0.00452879,1.00866 beta-lactamase_625_T147D,beta-lactamase_625_147,TEM-1,beta-lactamase_625,P62593,1.00866,NO,147,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.149,-3.491,2.342,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.213352,0.00226017,1.00866 beta-lactamase_G251K,beta-lactamase_251,TEM-1,beta-lactamase,P62593,1.00866,NO,251,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.907,-2.937,1.03,5.33865,0.506,T,l,0.73,0.17,10.663,,65.38,AOB,-2.06067,0.221079,0.00733416,1.00866 beta-lactamase_156_D36F,beta-lactamase_156_36,TEM-1,beta-lactamase_156,P62593,1.00867,NO,36,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.732,-4.318,1.586,,0.555,H,A,0.75,1.17,14.871,14.871,77.62,AAP,-1.91167,0.111618,0.00476483,1.00867 beta-lactamase_625_K32T,beta-lactamase_625_32,TEM-1,beta-lactamase_625,P62593,1.00867,NO,32,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.984,-2.479,0.495,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.213352,0.00401283,1.00867 hsp90_W585L,hsp90_585,hsp90,hsp90,P02829,1.00867,NO,585,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-4.251,-2.511,0,5.31455,0.508,,B,1.22,0.43,,,,OHP,-3.17533,0.368192,0.000222939,1.00867 beta-lactamase_0_K71H,beta-lactamase_0_71,TEM-1,beta-lactamase_0,P62593,1.00868,NO,71,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-0.8,-4.455,3.655,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.0500837,0.00103192,1.00868 beta-lactamase_625_T138P,beta-lactamase_625_138,TEM-1,beta-lactamase_625,P62593,1.00868,NO,138,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.506,-3.038,0.532,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.213352,0.00487868,1.00868 beta-lactamase_39_P165K,beta-lactamase_39_165,TEM-1,beta-lactamase_39,P62593,1.00869,NO,165,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.373,-3.528,2.155,,0.203,T,A,0.52,-0.31,3.907,,73.78,AOA,-1.359,0.0495842,0.00549538,1.00869 kka2_1:4_G164D,kka2_1:4_164,Kka2,kka2_1:4,P00552,1.00869,NO,164,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.869,-2.664,1.795,,0.862,T,l,0.75,1.45,1.539,,64.39,POH,-1.828,0.168804,0.00442091,1.00869 kka2_1:4_K138G,kka2_1:4_138,Kka2,kka2_1:4,P00552,1.0087,NO,138,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-2.5,-2.938,0.438,,0.594,H,A,1.3,0.98,21.267,21.267,71.59,HBB,-2.48833,0.168804,0.00628542,1.0087 Pab1_A141T,Pab1_141,Pab1,Pab1,P04147,1.00871,NO,141,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.461,-1.714,0.253,,0.34,H,A,0.52,-0.27,2.15,,79.03,BHH,-1.19433,0.175299,0.00165974,1.00871 beta-lactamase_156_K109P,beta-lactamase_156_109,TEM-1,beta-lactamase_156,P62593,1.00873,NO,109,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.734,-2.825,1.091,,0.787,G,A,2.34,2.21,6.031,,72.73,ABB,-1.63333,0.111618,0.00462493,1.00873 beta-lactamase_2500_A200N,beta-lactamase_2500_200,TEM-1,beta-lactamase_2500,P62593,1.00875,NO,200,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.878,-3.758,1.88,,0.757,H,A,0.46,-0.19,0.436,,77.62,HHP,-2.001,0.361275,0.0060056,1.00875 beta-lactamase_2500_Q88E,beta-lactamase_2500_88,TEM-1,beta-lactamase_2500,P62593,1.00875,NO,88,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.086,-2.76,0.674,,0.807,,B,0.64,2.03,1.84,,77.62,APH,-1.53433,0.361275,0.00504167,1.00875 beta-lactamase_625_Q267Y,beta-lactamase_625_267,TEM-1,beta-lactamase_625,P62593,1.00875,NO,267,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.213352,0.0102128,1.00875 beta-lactamase_625_R275A,beta-lactamase_625_275,TEM-1,beta-lactamase_625,P62593,1.00875,NO,275,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.213352,0.0141984,1.00875 beta-lactamase_39_Q267R,beta-lactamase_39_267,TEM-1,beta-lactamase_39,P62593,1.00876,NO,267,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.0495842,0.0102128,1.00876 beta-lactamase_625_R159M,beta-lactamase_625_159,TEM-1,beta-lactamase_625,P62593,1.00876,NO,159,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-0.94,-4.529,3.589,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.213352,0.00108472,1.00876 beta-lactamase_156_G39N,beta-lactamase_156_39,TEM-1,beta-lactamase_156,P62593,1.00877,NO,39,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.864,-2.55,0.686,,0.701,T,L,0.29,0.47,1.454,,77.62,HOH,-1.53633,0.111618,0.00487611,1.00877 beta-lactamase_156_S201N,beta-lactamase_156_201,TEM-1,beta-lactamase_156,P62593,1.00877,NO,201,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.183,-3.471,2.288,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.111618,0.00198815,1.00877 beta-lactamase_39_E119D,beta-lactamase_39_119,TEM-1,beta-lactamase_39,P62593,1.00877,NO,119,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.412,-2.093,0.681,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.0495842,0.00386966,1.00877 beta-lactamase_39_L199Q,beta-lactamase_39_199,TEM-1,beta-lactamase_39,P62593,1.00877,NO,199,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-2.942,-3.22,0.278,,0.832,H,A,0.55,0.42,15.504,15.504,77.62,PHH,-2.32933,0.0495842,0.0048649,1.00877 beta-lactamase_M153S,beta-lactamase_153,TEM-1,beta-lactamase,P62593,1.00877,NO,153,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-3.193,-2.433,-0.76,5.46509,0.14,T,A,1.07,-0.11,2.061,,77.62,PHO,-2.25767,0.221079,0.00509109,1.00877 beta-lactamase_156_P217D,beta-lactamase_156_217,TEM-1,beta-lactamase_156,P62593,1.00878,NO,217,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-2.062,-2.498,0.436,,0.496,I,A,0.52,-0.33,2.303,,74.48,OOH,-1.64333,0.111618,0.00463211,1.00878 beta-lactamase_2500_H151G,beta-lactamase_2500_151,TEM-1,beta-lactamase_2500,P62593,1.00878,NO,151,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-2.96,-2.515,-0.445,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.361275,0.00216946,1.00878 beta-lactamase_39_A148G,beta-lactamase_39_148,TEM-1,beta-lactamase_39,P62593,1.00878,NO,148,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.757,-2.542,0.785,,0.379,H,A,0.46,-0.55,3.551,,72.73,PHH,-1.40167,0.0495842,0.00547053,1.00878 beta-lactamase_39_L73M,beta-lactamase_39_73,TEM-1,beta-lactamase_39,P62593,1.00878,NO,73,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.507,-2.898,1.391,,,H,A,0.55,-0.64,2.09,,67.83,HHH,-1.487,0.0495842,0.00488983,1.00878 Pab1_P200S,Pab1_200,Pab1,Pab1,P04147,1.00878,NO,200,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.871,-3.348,1.477,,,,,,,3.877,,80.59,HOO,-1.7005,0.175299,0.00190795,1.00878 beta-lactamase_156_T186C,beta-lactamase_156_186,TEM-1,beta-lactamase_156,P62593,1.00879,NO,186,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.522,-5.021,2.499,,0.396,H,A,0.22,-0.28,16.606,16.606,77.62,HPP,-1.77633,0.111618,0.00485034,1.00879 beta-lactamase_2500_V29T,beta-lactamase_2500_29,TEM-1,beta-lactamase_2500,P62593,1.00879,NO,29,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-2.856,-2.552,-0.304,,0.733,H,A,0.44,-0.78,1.931,,93.01,HHB,-2.24733,0.361275,0.00318969,1.00879 beta-lactamase_39_Q86R,beta-lactamase_39_86,TEM-1,beta-lactamase_39,P62593,1.00879,NO,86,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.4,-2.686,0.286,,0.696,S,A,0.64,2.38,27.704,27.704,77.62,OPA,-1.61067,0.0495842,0.00450027,1.00879 beta-lactamase_625_L146A,beta-lactamase_625_146,TEM-1,beta-lactamase_625,P62593,1.00879,NO,146,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.462,-3.204,1.742,,0.007,H,A,0.55,-0.56,2.16,,64.69,AHP,-1.656,0.213352,0.00474542,1.00879 beta-lactamase_S68S,beta-lactamase_68,TEM-1,beta-lactamase,P62593,1.00879,NO,68,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-0.913,-0.913,,4.94745,0.064,G,A,0.77,-1.03,3.202,,64.69,HPP,-1.37233,0.221079,0.000800065,1.00879 Pab1_E161A,Pab1_161,Pab1,Pab1,P04147,1.00879,NO,161,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.474,-2.253,0.779,,0.663,T,a,,1.34,,,,AAP,-1.59067,0.175299,0.00276141,1.00879 beta-lactamase_625_S51V,beta-lactamase_625_51,TEM-1,beta-lactamase_625,P62593,1.0088,NO,51,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.526,-3.559,2.033,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.213352,0.00504821,1.0088 beta-lactamase_156_G141H,beta-lactamase_156_141,TEM-1,beta-lactamase_156,P62593,1.00881,NO,141,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.828,-4.652,3.824,,0.575,T,l,0.29,-0.28,0.198,,64.69,HOO,-1.08933,0.111618,0.0012419,1.00881 beta-lactamase_156_L196C,beta-lactamase_156_196,TEM-1,beta-lactamase_156,P62593,1.00881,NO,196,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-2.478,-4.975,2.497,,0.518,S,A,0.55,1.35,7.897,,77.62,AHH,-1.839,0.111618,0.00512144,1.00881 beta-lactamase_156_S57V,beta-lactamase_156_57,TEM-1,beta-lactamase_156,P62593,1.00882,NO,57,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.918,-2.889,0.971,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.111618,0.00492804,1.00882 PSD95pdz3_F337L,PSD95pdz3_337,PSD95pdz3,PSD95pdz3,P31016,1.00882,NO,337,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.524,-2.59,1.066,5.22838,,,,,13.4936,,,,HHH,-1.59467,0.0758425,0.000875287,1.00882 beta-lactamase_2500_L196C,beta-lactamase_2500_196,TEM-1,beta-lactamase_2500,P62593,1.00883,NO,196,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-2.478,-4.975,2.497,,0.518,S,A,0.55,1.35,7.897,,77.62,AHH,-1.839,0.361275,0.00512144,1.00883 beta-lactamase_625_L197F,beta-lactamase_625_197,TEM-1,beta-lactamase_625,P62593,1.00883,NO,197,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.853,-3.685,2.832,,0.007,S,B,0.55,0.33,1.756,,60.14,HHP,-1.833,0.213352,0.00144602,1.00883 kka2_1:4_S204G,kka2_1:4_204,Kka2,kka2_1:4,P00552,1.00883,NO,204,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.353,-2.544,1.191,,0.144,E,A,0.27,-1.2,2.442,,65.53,HPO,-0.953333,0.168804,0.00881794,1.00883 beta-lactamase_156_L188W,beta-lactamase_156_188,TEM-1,beta-lactamase_156,P62593,1.00884,NO,188,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.166,-3.108,1.942,,,H,A,0.55,-0.3,1.574,,60.14,PHB,-1.47033,0.111618,0.00295687,1.00884 beta-lactamase_156_L219F,beta-lactamase_156_219,TEM-1,beta-lactamase_156,P62593,1.00884,NO,219,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.313,-2.825,1.512,,,I,A,0.55,-0.51,2.321,,74.48,HHB,-1.21533,0.111618,0.00664345,1.00884 beta-lactamase_156_T27Q,beta-lactamase_156_27,TEM-1,beta-lactamase_156,P62593,1.00884,NO,27,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.905,-3.929,2.024,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.111618,0.00306559,1.00884 WW_domain_A175P,WW_domain_175,Yap65,WW_domain,P46937,1.00884,NO,175,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.631,-1.656,0.025,6.69537,,,,,,6.257,,83.93,OHO,-1.30033,0.153962,0.00326874,1.00884 beta-lactamase_156_R189W,beta-lactamase_156_189,TEM-1,beta-lactamase_156,P62593,1.00885,NO,189,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.844,-5.37,3.526,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.111618,0.0050699,1.00885 beta-lactamase_39_I245A,beta-lactamase_39_245,TEM-1,beta-lactamase_39,P62593,1.00885,NO,245,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.068,-3.611,2.543,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.0495842,0.00391032,1.00885 Pab1_P200N,Pab1_200,Pab1,Pab1,P04147,1.00885,NO,200,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.871,-3.838,1.967,,,,,,,3.877,,80.59,HOO,-1.7005,0.175299,0.00190795,1.00885 beta-lactamase_625_L135A,beta-lactamase_625_135,TEM-1,beta-lactamase_625,P62593,1.00886,NO,135,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.002,-3.131,2.129,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.213352,0.00244423,1.00886 beta-lactamase_625_L135I,beta-lactamase_625_135,TEM-1,beta-lactamase_625,P62593,1.00886,NO,135,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.002,-2.037,1.035,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.213352,0.00244423,1.00886 beta-lactamase_156_E210M,beta-lactamase_156_210,TEM-1,beta-lactamase_156,P62593,1.00887,NO,210,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.319,-4.371,2.052,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.111618,0.00663582,1.00887 beta-lactamase_156_K190C,beta-lactamase_156_190,TEM-1,beta-lactamase_156,P62593,1.00887,NO,190,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.994,-5.082,3.088,,0.371,H,A,2.34,0.16,1.513,,77.62,BBH,-1.64167,0.111618,0.00574527,1.00887 beta-lactamase_39_R242I,beta-lactamase_39_242,TEM-1,beta-lactamase_39,P62593,1.00887,NO,242,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.0495842,0.00452879,1.00887 kka2_1:8_Q136K,kka2_1:8_136,Kka2,kka2_1:8,P00552,1.00887,NO,136,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-3.021,-3.273,0.252,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.100394,0.00624149,1.00887 kka2_1:8_Q136K,kka2_1:8_136,Kka2,kka2_1:8,P00552,1.00887,NO,136,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-3.021,-3.273,0.252,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.100394,0.00624149,1.00887 beta-lactamase_39_I45C,beta-lactamase_39_45,TEM-1,beta-lactamase_39,P62593,1.00888,NO,45,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-2.421,-4.903,2.482,,,E,B,0.48,-0.3,2.256,,77.62,HHA,-2.30267,0.0495842,0.00452842,1.00888 beta-lactamase_625_A278V,beta-lactamase_625_278,TEM-1,beta-lactamase_625,P62593,1.00888,NO,278,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.213352,0.0310297,1.00888 beta-lactamase_A84T,beta-lactamase_84,TEM-1,beta-lactamase,P62593,1.00888,NO,84,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.651,-2.88,1.229,5.28927,0.65,T,A,0.52,0.96,1.863,,68.18,AHO,-1.24267,0.221079,0.00503822,1.00888 beta-lactamase_E119E,beta-lactamase_119,TEM-1,beta-lactamase,P62593,1.00888,NO,119,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.412,-1.412,,5.33349,0.358,H,A,1.52,0.51,1.983,,63.99,BAH,-1.623,0.221079,0.00386966,1.00888 beta-lactamase_H24G,beta-lactamase_24,TEM-1,beta-lactamase,P62593,1.00888,NO,24,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-2.481,-2.499,0.018,5.82767,,,,,,2.708,,93.01,HBO,-1.85167,0.221079,0.00238894,1.00888 beta-lactamase_156_D99S,beta-lactamase_156_99,TEM-1,beta-lactamase_156,P62593,1.00889,NO,99,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.191,-3.286,2.095,,0.402,G,A,0.75,0.36,3.529,,64.69,PAH,-1.794,0.111618,0.00305446,1.00889 beta-lactamase_39_E195G,beta-lactamase_39_195,TEM-1,beta-lactamase_39,P62593,1.00889,NO,195,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.186,-2.611,0.425,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.0495842,0.00496565,1.00889 beta-lactamase_625_Q86W,beta-lactamase_625_86,TEM-1,beta-lactamase_625,P62593,1.00889,NO,86,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.4,-5.489,3.089,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.213352,0.00450027,1.00889 beta-lactamase_625_T186Y,beta-lactamase_625_186,TEM-1,beta-lactamase_625,P62593,1.00889,NO,186,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.522,-4.364,1.842,,0.396,H,A,0.22,-0.28,0.515,,77.62,HPP,-1.77633,0.213352,0.00485034,1.00889 beta-lactamase_Q203Q,beta-lactamase_203,TEM-1,beta-lactamase,P62593,1.00889,NO,203,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.168,-2.168,,5.65296,0.47,H,A,0.12,-0.38,1.66,,65.38,BPP,-1.614,0.221079,0.00631514,1.00889 beta-lactamase_39_E145M,beta-lactamase_39_145,TEM-1,beta-lactamase_39,P62593,1.0089,NO,145,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.357,-4.807,2.45,,0.545,H,A,1.04,0.79,1.199,,77.62,BAH,-2.069,0.0495842,0.00553285,1.0089 beta-lactamase_156_L223G,beta-lactamase_156_223,TEM-1,beta-lactamase_156,P62593,1.00891,NO,223,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.055,-3.765,2.71,,0.27,,B,0.55,0.09,1.511,,74.48,HHO,-1.35033,0.111618,0.00372793,1.00891 beta-lactamase_156_V82A,beta-lactamase_156_82,TEM-1,beta-lactamase_156,P62593,1.00891,NO,82,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.325,-2.13,0.805,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.111618,0.00397046,1.00891 beta-lactamase_625_S241C,beta-lactamase_625_241,TEM-1,beta-lactamase_625,P62593,1.00891,NO,241,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.213352,0.00452736,1.00891 beta-lactamase_156_N173Y,beta-lactamase_156_173,TEM-1,beta-lactamase_156,P62593,1.00892,NO,173,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-2.663,-4.409,1.746,,1.044,T,l,0.61,1.25,3.718,,77.62,OPA,-1.46633,0.111618,0.0033769,1.00892 beta-lactamase_39_I140E,beta-lactamase_39_140,TEM-1,beta-lactamase_39,P62593,1.00892,NO,140,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.733,-3.925,2.192,,0.128,H,A,0.48,0.41,1.16,,73.08,PHO,-1.48733,0.0495842,0.00597777,1.00892 beta-lactamase_625_L284T,beta-lactamase_625_284,TEM-1,beta-lactamase_625,P62593,1.00892,NO,284,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.213352,0.0686156,1.00892 beta-lactamase_625_P255H,beta-lactamase_625_255,TEM-1,beta-lactamase_625,P62593,1.00892,NO,255,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.213352,0.00499612,1.00892 beta-lactamase_N98Y,beta-lactamase_98,TEM-1,beta-lactamase,P62593,1.00892,NO,98,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-2.973,-4.22,1.247,6.59973,0.963,G,A,1.07,1.35,1.332,,77.62,PPA,-2.07867,0.221079,0.00505389,1.00892 gb1_V255Y,gb1_255,gb1,gb1,P06654,1.00892,NO,255,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-3.127,-1.979,-1.148,,,,,,,1.323,,45.54,BHH,-2.03867,0.177985,0.00408354,1.00892 beta-lactamase_156_R189H,beta-lactamase_156_189,TEM-1,beta-lactamase_156,P62593,1.00893,NO,189,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.844,-2.544,0.7,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.111618,0.0050699,1.00893 beta-lactamase_156_R202W,beta-lactamase_156_202,TEM-1,beta-lactamase_156,P62593,1.00893,NO,202,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.292,-5.342,4.05,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.111618,0.00321899,1.00893 beta-lactamase_156_T186A,beta-lactamase_156_186,TEM-1,beta-lactamase_156,P62593,1.00893,NO,186,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.522,-1.898,-0.624,,0.396,H,A,0.22,-0.28,16.606,16.606,77.62,HPP,-1.77633,0.111618,0.00485034,1.00893 beta-lactamase_625_A183V,beta-lactamase_625_183,TEM-1,beta-lactamase_625,P62593,1.00893,NO,183,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.231,-3.28,2.049,,0.155,H,A,0.46,-0.91,23.859,23.859,77.62,HHH,-1.53367,0.213352,0.00296631,1.00893 kka2_1:8_T85E,kka2_1:8_85,Kka2,kka2_1:8,P00552,1.00893,NO,85,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.165,-2.512,0.347,,0.576,E,B,0.22,1.39,22.154,22.154,71.59,HPA,-2.10133,0.100394,0.00634493,1.00893 kka2_1:8_T85E,kka2_1:8_85,Kka2,kka2_1:8,P00552,1.00893,NO,85,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.165,-2.512,0.347,,0.576,E,B,0.22,1.39,22.154,22.154,71.59,HPA,-2.10133,0.100394,0.00634493,1.00893 beta-lactamase_156_A200R,beta-lactamase_156_200,TEM-1,beta-lactamase_156,P62593,1.00894,NO,200,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.878,-2.634,0.756,,0.757,H,A,0.46,-0.19,16.368,16.368,77.62,HHP,-2.001,0.111618,0.0060056,1.00894 beta-lactamase_39_W227M,beta-lactamase_39_227,TEM-1,beta-lactamase_39,P62593,1.00894,NO,227,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-0.982,-4.54,3.558,,0.272,,B,0.47,-0.29,1.37,,74.48,OHH,-1.595,0.0495842,0.00226019,1.00894 beta-lactamase_156_R63Y,beta-lactamase_156_63,TEM-1,beta-lactamase_156,P62593,1.00895,NO,63,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-0.943,-4.16,3.217,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.111618,0.00126938,1.00895 beta-lactamase_625_S122T,beta-lactamase_625_122,TEM-1,beta-lactamase_625,P62593,1.00895,NO,122,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.406,-2.952,0.546,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.213352,0.00497825,1.00895 kka2_1:2_W15G,kka2_1:2_15,Kka2,kka2_1:2,P00552,1.00895,NO,15,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-1.392,-3.656,2.264,,0.01,G,A,0.47,0.15,2.586,,52.27,HHH,-2.10533,0.295029,0.00585505,1.00895 beta-lactamase_156_L197K,beta-lactamase_156_197,TEM-1,beta-lactamase_156,P62593,1.00896,NO,197,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.853,-3.679,2.826,,0.007,S,B,0.55,0.33,1.58,,60.14,HHP,-1.833,0.111618,0.00144602,1.00896 beta-lactamase_2500_E108I,beta-lactamase_2500_108,TEM-1,beta-lactamase_2500,P62593,1.00896,NO,108,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.46,-4.133,2.673,,0.572,G,A,1.04,1.87,1.147,,72.73,PAB,-1.437,0.361275,0.00413372,1.00896 beta-lactamase_39_T158V,beta-lactamase_39_158,TEM-1,beta-lactamase_39,P62593,1.00896,NO,158,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.116,-3.299,2.183,,0.036,,B,0.22,-0.85,2.755,,69.58,HPB,-1.269,0.0495842,0.00341825,1.00896 beta-lactamase_625_R202G,beta-lactamase_625_202,TEM-1,beta-lactamase_625,P62593,1.00896,NO,202,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.292,-3.349,2.057,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.213352,0.00321899,1.00896 beta-lactamase_39_T138G,beta-lactamase_39_138,TEM-1,beta-lactamase_39,P62593,1.00897,NO,138,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.506,-2.767,0.261,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.0495842,0.00487868,1.00897 beta-lactamase_625_M127G,beta-lactamase_625_127,TEM-1,beta-lactamase_625,P62593,1.00897,NO,127,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-2.251,-3.785,1.534,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.213352,0.00437927,1.00897 beta-lactamase_156_L79C,beta-lactamase_156_79,TEM-1,beta-lactamase_156,P62593,1.00898,NO,79,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.842,-4.663,3.821,,0.007,H,A,0.55,-0.16,1.831,,50.35,HHP,-1.44333,0.111618,0.000947397,1.00898 beta-lactamase_39_L73N,beta-lactamase_39_73,TEM-1,beta-lactamase_39,P62593,1.00898,NO,73,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.507,-4.234,2.727,,,H,A,0.55,-0.64,2.09,,67.83,HHH,-1.487,0.0495842,0.00488983,1.00898 beta-lactamase_625_K32W,beta-lactamase_625_32,TEM-1,beta-lactamase_625,P62593,1.00898,NO,32,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.984,-5.48,3.496,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.213352,0.00401283,1.00898 PSD95pdz3_S350D,PSD95pdz3_350,PSD95pdz3,PSD95pdz3,P31016,1.00898,NO,350,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.519,-2.925,1.406,4.97629,,,,,25.01,,,,HPO,-1.29133,0.0758425,0.000704883,1.00898 beta-lactamase_156_N173V,beta-lactamase_156_173,TEM-1,beta-lactamase_156,P62593,1.00899,NO,173,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-2.663,-3.738,1.075,,1.044,T,l,0.61,1.25,3.718,,77.62,OPA,-1.46633,0.111618,0.0033769,1.00899 beta-lactamase_39_S201T,beta-lactamase_39_201,TEM-1,beta-lactamase_39,P62593,1.00899,NO,201,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.183,-3.198,2.015,,0.064,H,A,0.27,-0.07,3.54,,64.69,HPB,-1.451,0.0495842,0.00198815,1.00899 beta-lactamase_39_E61V,beta-lactamase_39_61,TEM-1,beta-lactamase_39,P62593,1.009,NO,61,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.115,-3.784,1.669,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.0495842,0.00440955,1.009 beta-lactamase_625_P217T,beta-lactamase_625_217,TEM-1,beta-lactamase_625,P62593,1.009,NO,217,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-2.062,-2.679,0.617,,0.496,I,A,0.52,-0.33,1.087,,74.48,OOH,-1.64333,0.213352,0.00463211,1.009 beta-lactamase_625_P217V,beta-lactamase_625_217,TEM-1,beta-lactamase_625,P62593,1.009,NO,217,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-2.062,-3.65,1.588,,0.496,I,A,0.52,-0.33,1.087,,74.48,OOH,-1.64333,0.213352,0.00463211,1.009 beta-lactamase_Q37E,beta-lactamase_37,TEM-1,beta-lactamase,P62593,1.009,NO,37,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.134,-2.427,0.293,5.69153,0.613,H,A,0.12,1.98,1.318,,73.08,APH,-2.06967,0.221079,0.00425833,1.009 beta-lactamase_156_E87W,beta-lactamase_156_87,TEM-1,beta-lactamase_156,P62593,1.00901,NO,87,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.421,-5.437,4.016,,0.048,,B,1.04,0.92,1.754,,64.69,PAP,-1.969,0.111618,0.00337888,1.00901 beta-lactamase_156_T138G,beta-lactamase_156_138,TEM-1,beta-lactamase_156,P62593,1.00901,NO,138,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.506,-2.767,0.261,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.111618,0.00487868,1.00901 beta-lactamase_39_L89W,beta-lactamase_39_89,TEM-1,beta-lactamase_39,P62593,1.00901,NO,89,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.096,-5.236,4.14,,0.168,T,A,0.55,0.63,3.233,,64.34,PHO,-1.75767,0.0495842,0.00207068,1.00901 beta-lactamase_39_P255L,beta-lactamase_39_255,TEM-1,beta-lactamase_39,P62593,1.00901,NO,255,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.0495842,0.00499612,1.00901 beta-lactamase_156_S80C,beta-lactamase_156_80,TEM-1,beta-lactamase_156,P62593,1.00902,NO,80,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.029,-4.922,2.893,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.111618,0.00565569,1.00902 beta-lactamase_2500_E61Q,beta-lactamase_2500_61,TEM-1,beta-lactamase_2500,P62593,1.00902,NO,61,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.115,-2.702,0.587,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.361275,0.00440955,1.00902 beta-lactamase_39_I140H,beta-lactamase_39_140,TEM-1,beta-lactamase_39,P62593,1.00902,NO,140,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.733,-4.991,3.258,,0.128,H,A,0.48,0.41,1.16,,73.08,PHO,-1.48733,0.0495842,0.00597777,1.00902 beta-lactamase_156_R59M,beta-lactamase_156_59,TEM-1,beta-lactamase_156,P62593,1.00903,NO,59,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.345,-4.605,3.26,,0.329,S,L,1.2,-0.09,2.995,,73.08,HBO,-2.24267,0.111618,0.00318082,1.00903 beta-lactamase_156_A170E,beta-lactamase_156_170,TEM-1,beta-lactamase_156,P62593,1.00904,NO,170,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.237,-3.626,2.389,,0.126,,L,0.46,-0.35,3.7,,64.69,AHH,-1.63267,0.111618,0.00431903,1.00904 beta-lactamase_156_R92T,beta-lactamase_156_92,TEM-1,beta-lactamase_156,P62593,1.00904,NO,92,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.718,-2.88,1.162,,0.479,E,B,1.2,1.36,19.112,19.112,65.38,BBH,-1.50367,0.111618,0.00429626,1.00904 beta-lactamase_2500_R118D,beta-lactamase_2500_118,TEM-1,beta-lactamase_2500,P62593,1.00904,NO,118,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.413,-2.866,0.453,,0.457,H,A,1.2,1.39,2.144,,77.62,HBA,-1.785,0.361275,0.00538794,1.00904 beta-lactamase_39_E238V,beta-lactamase_39_238,TEM-1,beta-lactamase_39,P62593,1.00904,NO,238,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.0495842,0.00743256,1.00904 beta-lactamase_39_K190C,beta-lactamase_39_190,TEM-1,beta-lactamase_39,P62593,1.00904,NO,190,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.994,-5.082,3.088,,0.371,H,A,2.34,0.16,1.513,,77.62,BBH,-1.64167,0.0495842,0.00574527,1.00904 beta-lactamase_39_E175H,beta-lactamase_39_175,TEM-1,beta-lactamase_39,P62593,1.00905,NO,175,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.336,-3.355,1.019,,0.551,,A,1.04,1.05,3.676,,77.62,AAB,-1.31233,0.0495842,0.00482205,1.00905 beta-lactamase_625_A77M,beta-lactamase_625_77,TEM-1,beta-lactamase_625,P62593,1.00905,NO,77,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.234,-4.524,3.29,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.213352,0.00282362,1.00905 beta-lactamase_N98I,beta-lactamase_98,TEM-1,beta-lactamase,P62593,1.00905,NO,98,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-2.973,-4.064,1.091,6.59973,0.963,G,A,1.07,1.35,1.332,,77.62,PPA,-2.07867,0.221079,0.00505389,1.00905 beta-lactamase_156_I140C,beta-lactamase_156_140,TEM-1,beta-lactamase_156,P62593,1.00906,NO,140,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.733,-4.792,3.059,,0.128,H,A,0.48,0.41,1.16,,73.08,PHO,-1.48733,0.111618,0.00597777,1.00906 beta-lactamase_625_T186Q,beta-lactamase_625_186,TEM-1,beta-lactamase_625,P62593,1.00906,NO,186,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.522,-2.514,-0.008,,0.396,H,A,0.22,-0.28,0.515,,77.62,HPP,-1.77633,0.213352,0.00485034,1.00906 beta-lactamase_156_P65I,beta-lactamase_156_65,TEM-1,beta-lactamase_156,P62593,1.00907,NO,65,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.894,-3.716,2.822,,0.098,E,B,0.52,-0.62,0.623,,40.56,HOH,-1.03233,0.111618,0.00152776,1.00907 beta-lactamase_39_L38G,beta-lactamase_39_38,TEM-1,beta-lactamase_39,P62593,1.00907,NO,38,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.343,-3.696,2.353,,0.088,H,A,0.55,0.2,17.089,17.089,64.34,PHO,-1.78033,0.0495842,0.00373244,1.00907 beta-lactamase_625_R239D,beta-lactamase_625_239,TEM-1,beta-lactamase_625,P62593,1.00907,NO,239,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.213352,0.00213852,1.00907 beta-lactamase_156_H156F,beta-lactamase_156_156,TEM-1,beta-lactamase_156,P62593,1.00908,NO,156,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-3.156,-4.428,1.272,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.111618,0.00468596,1.00908 beta-lactamase_2500_A282R,beta-lactamase_2500_282,TEM-1,beta-lactamase_2500,P62593,1.00908,NO,282,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.361275,0.0449821,1.00908 beta-lactamase_625_G76T,beta-lactamase_625_76,TEM-1,beta-lactamase_625,P62593,1.00908,NO,76,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.189,-2.655,1.466,,,H,A,0.29,-0.67,3.059,,67.83,OOH,-1.22267,0.213352,0.00476637,1.00908 beta-lactamase_625_R273L,beta-lactamase_625_273,TEM-1,beta-lactamase_625,P62593,1.00908,NO,273,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.314,-3.556,1.242,,0.564,H,A,1.2,1.57,1.455,,73.78,ABP,-1.841,0.213352,0.0077952,1.00908 beta-lactamase_2500_H151A,beta-lactamase_2500_151,TEM-1,beta-lactamase_2500,P62593,1.00909,NO,151,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-2.96,-3.11,0.15,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.361275,0.00216946,1.00909 beta-lactamase_39_A230Y,beta-lactamase_39_230,TEM-1,beta-lactamase_39,P62593,1.00909,NO,230,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.154,-4.312,3.158,,0.01,E,B,0.46,-1.17,1.171,,50,HHA,-1.079,0.0495842,0.00516841,1.00909 beta-lactamase_39_H156D,beta-lactamase_39_156,TEM-1,beta-lactamase_39,P62593,1.00909,NO,156,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-3.156,-2.458,-0.698,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.0495842,0.00468596,1.00909 Pab1_E174K,Pab1_174,Pab1,Pab1,P04147,1.00909,NO,174,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.422,-2.194,0.772,,0.578,S,A,,0.38,,,,HAA,-1.65133,0.175299,0.00077863,1.00909 beta-lactamase_156_L89M,beta-lactamase_156_89,TEM-1,beta-lactamase_156,P62593,1.0091,NO,89,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.096,-2.928,1.832,,0.168,T,A,0.55,0.63,2.633,,64.34,PHO,-1.75767,0.111618,0.00207068,1.0091 beta-lactamase_39_S256D,beta-lactamase_39_256,TEM-1,beta-lactamase_39,P62593,1.0091,NO,256,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.0495842,0.00710634,1.0091 kka2_1:4_D118T,kka2_1:4_118,Kka2,kka2_1:4,P00552,1.0091,NO,118,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.07,-2.449,0.379,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.168804,0.0067852,1.0091 beta-lactamase_39_I206V,beta-lactamase_39_206,TEM-1,beta-lactamase_39,P62593,1.00911,NO,206,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-2.429,-2.433,0.004,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.0495842,0.00528934,1.00911 beta-lactamase_E169W,beta-lactamase_169,TEM-1,beta-lactamase,P62593,1.00911,NO,169,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.23,-5.379,4.149,5.78896,0.337,,A,0.52,1,1.806,,73.08,PAH,-1.16533,0.221079,0.00400994,1.00911 beta-lactamase_156_A278Q,beta-lactamase_156_278,TEM-1,beta-lactamase_156,P62593,1.00912,NO,278,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.111618,0.0310297,1.00912 beta-lactamase_39_H94Q,beta-lactamase_39_94,TEM-1,beta-lactamase_39,P62593,1.00912,NO,94,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-2.5,-3.155,0.655,,0.776,,B,0.17,1.24,11.583,11.583,77.62,HBH,-1.872,0.0495842,0.00389226,1.00912 beta-lactamase_625_I45T,beta-lactamase_625_45,TEM-1,beta-lactamase_625,P62593,1.00912,NO,45,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-2.421,-2.537,0.116,,,E,B,0.48,-0.3,3.642,,77.62,HHA,-2.30267,0.213352,0.00452842,1.00912 Pab1_E195S,Pab1_195,Pab1,Pab1,P04147,1.00912,NO,195,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.2,-3.031,1.831,,,,,,,,,,PAH,-1.72467,0.175299,0.000620107,1.00912 beta-lactamase_156_T116D,beta-lactamase_156_116,TEM-1,beta-lactamase_156,P62593,1.00913,NO,116,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.28,-3.524,2.244,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.111618,0.00336175,1.00913 beta-lactamase_39_G216P,beta-lactamase_39_216,TEM-1,beta-lactamase_39,P62593,1.00913,NO,216,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.477,-3.898,2.421,,0.437,I,A,0.29,-0.58,0.834,,74.48,HOO,-1.68067,0.0495842,0.00639568,1.00913 beta-lactamase_625_E175A,beta-lactamase_625_175,TEM-1,beta-lactamase_625,P62593,1.00913,NO,175,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.336,-2.1,-0.236,,0.551,,A,1.04,1.05,8.527,8.527,77.62,AAB,-1.31233,0.213352,0.00482205,1.00913 beta-lactamase_625_N152V,beta-lactamase_625_152,TEM-1,beta-lactamase_625,P62593,1.00913,NO,152,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-2.757,-3.616,0.859,,0.863,H,A,0.61,0.92,2.061,,77.62,BPH,-2.97,0.213352,0.00471429,1.00913 PSD95pdz3_I377L,PSD95pdz3_377,PSD95pdz3,PSD95pdz3,P31016,1.00913,NO,377,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.873,-1.909,0.036,4.9532,,,,,19.185,2.364,,87.71,HHH,-1.49567,0.0758425,0.000795475,1.00913 beta-lactamase_156_Q37M,beta-lactamase_156_37,TEM-1,beta-lactamase_156,P62593,1.00914,NO,37,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.134,-4.645,2.511,,0.613,H,A,0.64,1.98,12.052,12.052,73.08,APH,-2.06967,0.111618,0.00425833,1.00914 beta-lactamase_39_L49Y,beta-lactamase_39_49,TEM-1,beta-lactamase_39,P62593,1.00914,NO,49,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.897,-4.158,2.261,,0.131,T,A,0.55,0.04,13.838,13.838,64.69,AHP,-1.99233,0.0495842,0.00401477,1.00914 beta-lactamase_625_E238L,beta-lactamase_625_238,TEM-1,beta-lactamase_625,P62593,1.00914,NO,238,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.213352,0.00743256,1.00914 beta-lactamase_625_R41H,beta-lactamase_625_41,TEM-1,beta-lactamase_625,P62593,1.00914,NO,41,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-0.942,-4.279,3.337,,0.321,E,B,1.2,-0.07,1.186,,65.03,HBH,-1.30267,0.213352,0.00123327,1.00914 beta-lactamase_156_K232R,beta-lactamase_156_232,TEM-1,beta-lactamase_156,P62593,1.00916,NO,232,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.012,-1.888,0.876,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.111618,0.00313441,1.00916 beta-lactamase_2500_A148K,beta-lactamase_2500_148,TEM-1,beta-lactamase_2500,P62593,1.00916,NO,148,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.757,-2.857,1.1,,0.379,H,A,0.46,-0.55,2.117,,72.73,PHH,-1.40167,0.361275,0.00547053,1.00916 beta-lactamase_39_P60K,beta-lactamase_39_60,TEM-1,beta-lactamase_39,P62593,1.00916,NO,60,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-2.469,-3.557,1.088,,0.256,T,A,0.52,-0.56,21.37,21.37,77.62,BOA,-1.97633,0.0495842,0.00521318,1.00916 beta-lactamase_2500_P60S,beta-lactamase_2500_60,TEM-1,beta-lactamase_2500,P62593,1.00917,NO,60,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-2.469,-2.362,-0.107,,0.256,T,A,0.52,-0.56,1.581,,77.62,BOA,-1.97633,0.361275,0.00521318,1.00917 beta-lactamase_S122S,beta-lactamase_122,TEM-1,beta-lactamase,P62593,1.00917,NO,122,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.406,-2.406,,4.87767,0.352,H,A,0.73,-0.54,1.581,,77.62,OPH,-1.39767,0.221079,0.00497825,1.00917 Pab1_N162F,Pab1_162,Pab1,Pab1,P04147,1.00917,NO,162,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-2.313,-2.638,0.325,,0.681,T,A,,1.12,,,,APO,-1.532,0.175299,0.0030719,1.00917 beta-lactamase_2500_K109N,beta-lactamase_2500_109,TEM-1,beta-lactamase_2500,P62593,1.00918,NO,109,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.734,-2.767,1.033,,0.787,G,A,2.34,2.21,0.998,,72.73,ABB,-1.63333,0.361275,0.00462493,1.00918 beta-lactamase_39_T263Y,beta-lactamase_39_263,TEM-1,beta-lactamase_39,P62593,1.00918,NO,263,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.0495842,0.0110582,1.00918 beta-lactamase_625_E87F,beta-lactamase_625_87,TEM-1,beta-lactamase_625,P62593,1.00918,NO,87,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.421,-4.277,2.856,,0.048,,B,1.04,0.92,17.923,17.923,64.69,PAP,-1.969,0.213352,0.00337888,1.00918 kka2_1:4_N200A,kka2_1:4_200,Kka2,kka2_1:4,P00552,1.00918,NO,200,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-2.446,-2.325,-0.121,,0.756,T,L,0.61,-0.08,1.746,,64.39,APO,-2.08,0.168804,0.00838549,1.00918 beta-lactamase_39_V78I,beta-lactamase_39_78,TEM-1,beta-lactamase_39,P62593,1.00919,NO,78,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.459,-1.96,0.501,,,H,A,0.44,-0.47,1.132,,63.64,HHH,-1.17833,0.0495842,0.00492501,1.00919 beta-lactamase_A148Q,beta-lactamase_148,TEM-1,beta-lactamase,P62593,1.00919,NO,148,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.757,-3.083,1.326,5.28111,0.379,H,A,0.52,-0.55,2.117,,72.73,PHH,-1.40167,0.221079,0.00547053,1.00919 Pab1_L142F,Pab1_142,Pab1,Pab1,P04147,1.00919,NO,142,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.039,-3.434,2.395,,0.007,H,A,0.84,-0.65,,,,HHH,-1.487,0.175299,0.000335477,1.00919 beta-lactamase_2500_Q37R,beta-lactamase_2500_37,TEM-1,beta-lactamase_2500,P62593,1.0092,NO,37,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.134,-2.096,-0.038,,0.613,H,A,0.64,1.98,1.318,,73.08,APH,-2.06967,0.361275,0.00425833,1.0092 beta-lactamase_2500_T193M,beta-lactamase_2500_193,TEM-1,beta-lactamase_2500,P62593,1.0092,NO,193,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.914,-4.362,2.448,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.361275,0.00482669,1.0092 beta-lactamase_39_A123D,beta-lactamase_39_123,TEM-1,beta-lactamase_39,P62593,1.00921,NO,123,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.834,-3.743,2.909,,0.039,H,A,0.46,-0.72,0.705,,41.26,PHH,-1.47367,0.0495842,0.0010157,1.00921 beta-lactamase_39_P224Y,beta-lactamase_39_224,TEM-1,beta-lactamase_39,P62593,1.00921,NO,224,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.893,-4.387,3.494,,0.383,,B,0.52,-0.3,3.169,,74.48,HOH,-1.26433,0.0495842,0.00189564,1.00921 beta-lactamase_156_G39W,beta-lactamase_156_39,TEM-1,beta-lactamase_156,P62593,1.00922,NO,39,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.864,-5.517,3.653,,0.701,T,L,0.29,0.47,1.454,,77.62,HOH,-1.53633,0.111618,0.00487611,1.00922 beta-lactamase_156_I171V,beta-lactamase_156_171,TEM-1,beta-lactamase_156,P62593,1.00922,NO,171,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-2.431,-3.274,0.843,,0.361,,B,0.48,0.53,3.869,,77.62,HHO,-1.55533,0.111618,0.00623355,1.00922 beta-lactamase_625_L135Q,beta-lactamase_625_135,TEM-1,beta-lactamase_625,P62593,1.00922,NO,135,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.002,-4.162,3.16,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.213352,0.00244423,1.00922 beta-lactamase_625_R275L,beta-lactamase_625_275,TEM-1,beta-lactamase_625,P62593,1.00922,NO,275,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.213352,0.0141984,1.00922 beta-lactamase_A170V,beta-lactamase_170,TEM-1,beta-lactamase,P62593,1.00922,NO,170,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.237,-2.64,1.403,5.19261,0.126,,L,2.34,-0.35,2.427,,64.69,AHH,-1.63267,0.221079,0.00431903,1.00922 beta-lactamase_Q265T,beta-lactamase_265,TEM-1,beta-lactamase,P62593,1.00922,NO,265,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.58,-2.453,-0.127,6.62674,1.116,,A,0.03,1.17,12.514,12.514,69.58,PPH,-1.978,0.221079,0.00811926,1.00922 gb1_D272F,gb1_272,gb1,gb1,P06654,1.00922,NO,272,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.457,-4.158,2.701,,,,,,,0.234,,11.83,HAA,-1.54533,0.177985,0.00218257,1.00922 beta-lactamase_625_F58H,beta-lactamase_625_58,TEM-1,beta-lactamase_625,P62593,1.00923,NO,58,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-2.914,-2.092,-0.822,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.213352,0.00523369,1.00923 PSD95pdz3_I316N,PSD95pdz3_316,PSD95pdz3,PSD95pdz3,P31016,1.00923,NO,316,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.63,-3.805,2.175,5.46166,,,,,19.005,,,,HHB,-1.62733,0.0758425,0.00112762,1.00923 PSD95pdz3_V365C,PSD95pdz3_365,PSD95pdz3,PSD95pdz3,P31016,1.00925,NO,365,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.592,-4.318,2.726,5.03791,,,,,18.9657,2.364,,81.35,OHA,-1.288,0.0758425,0.000649764,1.00925 beta-lactamase_39_P255N,beta-lactamase_39_255,TEM-1,beta-lactamase_39,P62593,1.00926,NO,255,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.0495842,0.00499612,1.00926 beta-lactamase_625_L55Q,beta-lactamase_625_55,TEM-1,beta-lactamase_625,P62593,1.00926,NO,55,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.86,-3.156,1.296,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.213352,0.00403741,1.00926 beta-lactamase_156_K53G,beta-lactamase_156_53,TEM-1,beta-lactamase_156,P62593,1.00927,NO,53,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-2.313,-2.824,0.511,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.111618,0.00383383,1.00927 beta-lactamase_156_L196G,beta-lactamase_156_196,TEM-1,beta-lactamase_156,P62593,1.00927,NO,196,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-2.478,-2.91,0.432,,0.518,S,A,0.55,1.35,7.897,,77.62,AHH,-1.839,0.111618,0.00512144,1.00927 beta-lactamase_39_M270L,beta-lactamase_39_270,TEM-1,beta-lactamase_39,P62593,1.00927,NO,270,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.0495842,0.00767762,1.00927 beta-lactamase_39_P143R,beta-lactamase_39_143,TEM-1,beta-lactamase_39,P62593,1.00927,NO,143,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.967,-3.999,3.032,,0.075,H,A,0.52,-0.37,0.976,,66.78,OOB,-1.354,0.0495842,0.00114551,1.00927 beta-lactamase_156_P25V,beta-lactamase_156_25,TEM-1,beta-lactamase_156,P62593,1.00928,NO,25,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.526,-3.565,2.039,,0.624,H,A,0.52,0.14,1.079,,73.08,BOA,-2.15367,0.111618,0.00347571,1.00928 beta-lactamase_156_T264F,beta-lactamase_156_264,TEM-1,beta-lactamase_156,P62593,1.00928,NO,264,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.111618,0.0119399,1.00928 beta-lactamase_156_V72P,beta-lactamase_156_72,TEM-1,beta-lactamase_156,P62593,1.00928,NO,72,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.658,-2.442,0.784,,,H,A,0.44,-1.03,1.92,,65.73,BHH,-1.32167,0.111618,0.00501194,1.00928 beta-lactamase_39_L47R,beta-lactamase_39_47,TEM-1,beta-lactamase_39,P62593,1.00928,NO,47,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.876,-2.668,0.792,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.0495842,0.00439844,1.00928 beta-lactamase_39_P65H,beta-lactamase_39_65,TEM-1,beta-lactamase_39,P62593,1.00928,NO,65,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.894,-4.735,3.841,,0.098,E,B,0.52,-0.62,0.623,,40.56,HOH,-1.03233,0.0495842,0.00152776,1.00928 beta-lactamase_I171C,beta-lactamase_171,TEM-1,beta-lactamase,P62593,1.00928,NO,171,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-2.431,-4.938,2.507,5.22771,0.361,,B,1,0.53,1.66,,77.62,HHO,-1.55533,0.221079,0.00623355,1.00928 beta-lactamase_N173A,beta-lactamase_173,TEM-1,beta-lactamase,P62593,1.00928,NO,173,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-2.663,-2.432,-0.231,7.02497,1.044,T,l,0.09,1.25,1.88,,77.62,OPA,-1.46633,0.221079,0.0033769,1.00928 beta-lactamase_156_T131A,beta-lactamase_156_131,TEM-1,beta-lactamase_156,P62593,1.00929,NO,131,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.328,-2.085,0.757,,,H,A,0.22,-0.69,2.031,,67.48,PPH,-1.00867,0.111618,0.00345886,1.00929 beta-lactamase_625_A182T,beta-lactamase_625_182,TEM-1,beta-lactamase_625,P62593,1.00929,NO,182,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.777,-2.685,0.908,,0.136,H,A,0.46,-0.66,16.784,16.784,93.01,OHH,-1.27367,0.213352,0.00559099,1.00929 beta-lactamase_156_E145D,beta-lactamase_156_145,TEM-1,beta-lactamase_156,P62593,1.0093,NO,145,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.357,-3.52,1.163,,0.545,H,A,1.04,0.79,3.661,,77.62,BAH,-2.069,0.111618,0.00553285,1.0093 beta-lactamase_156_I206V,beta-lactamase_156_206,TEM-1,beta-lactamase_156,P62593,1.0093,NO,206,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-2.429,-2.433,0.004,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.111618,0.00528934,1.0093 beta-lactamase_156_I285Y,beta-lactamase_156_285,TEM-1,beta-lactamase_156,P62593,1.0093,NO,285,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.111618,0.101555,1.0093 beta-lactamase_39_Q267A,beta-lactamase_39_267,TEM-1,beta-lactamase_39,P62593,1.0093,NO,267,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.0495842,0.0102128,1.0093 beta-lactamase_625_K53C,beta-lactamase_625_53,TEM-1,beta-lactamase_625,P62593,1.0093,NO,53,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-2.313,-5.135,2.822,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.213352,0.00383383,1.0093 beta-lactamase_E175I,beta-lactamase_175,TEM-1,beta-lactamase,P62593,1.0093,NO,175,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.336,-3.797,1.461,6.0311,0.551,,A,0.75,1.05,5.316,,77.62,AAB,-1.31233,0.221079,0.00482205,1.0093 PSD95pdz3_T387N,PSD95pdz3_387,PSD95pdz3,PSD95pdz3,P31016,1.0093,NO,387,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.391,-3.13,1.739,5.20757,,,,,18.8043,,,,HPH,-1.49533,0.0758425,0.000167911,1.0093 beta-lactamase_156_I261T,beta-lactamase_156_261,TEM-1,beta-lactamase_156,P62593,1.00931,NO,261,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-2.88,-1.929,-0.951,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.111618,0.0123091,1.00931 beta-lactamase_156_Q37L,beta-lactamase_156_37,TEM-1,beta-lactamase_156,P62593,1.00931,NO,37,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.134,-2.893,0.759,,0.613,H,A,0.64,1.98,12.052,12.052,73.08,APH,-2.06967,0.111618,0.00425833,1.00931 beta-lactamase_2500_E238Q,beta-lactamase_2500_238,TEM-1,beta-lactamase_2500,P62593,1.00931,NO,238,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.361275,0.00743256,1.00931 beta-lactamase_0_S104R,beta-lactamase_0_104,TEM-1,beta-lactamase_0,P62593,1.00932,NO,104,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.015,-3.804,2.789,,0.04,,b,0.27,0.57,1.148,,63.29,HPO,-1.05267,0.0500837,0.00218083,1.00932 beta-lactamase_156_N274T,beta-lactamase_156_274,TEM-1,beta-lactamase_156,P62593,1.00932,NO,274,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.111618,0.0110418,1.00932 beta-lactamase_39_G85C,beta-lactamase_39_85,TEM-1,beta-lactamase_39,P62593,1.00932,NO,85,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.011,-5.172,4.161,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.0495842,0.00252173,1.00932 beta-lactamase_L111L,beta-lactamase_111,TEM-1,beta-lactamase,P62593,1.00932,NO,111,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.76,-1.76,,5.8705,0.328,T,A,0.84,0.93,3.836,,64.34,BHP,-1.884,0.221079,0.00480671,1.00932 kka2_1:2_P76A,kka2_1:2_76,Kka2,kka2_1:2,P00552,1.00932,NO,76,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.449,-1.98,0.531,,0.331,.,B,0.52,-0.41,0.345,,63.64,HOO,-1.662,0.295029,0.00625685,1.00932 beta-lactamase_156_S256F,beta-lactamase_156_256,TEM-1,beta-lactamase_156,P62593,1.00933,NO,256,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.111618,0.00710634,1.00933 beta-lactamase_0_D36S,beta-lactamase_0_36,TEM-1,beta-lactamase_0,P62593,1.00934,NO,36,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.732,-2.107,-0.625,,0.555,H,A,0.75,1.17,13.689,13.689,77.62,AAP,-1.91167,0.0500837,0.00476483,1.00934 beta-lactamase_625_D231A,beta-lactamase_625_231,TEM-1,beta-lactamase_625,P62593,1.00934,NO,231,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.816,-3.3,2.484,,,E,B,0.75,-1.06,1.025,,65.38,HAB,-0.994,0.213352,0.00107395,1.00934 beta-lactamase_2500_Q267K,beta-lactamase_2500_267,TEM-1,beta-lactamase_2500,P62593,1.00935,NO,267,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.361275,0.0102128,1.00935 beta-lactamase_39_A211F,beta-lactamase_39_211,TEM-1,beta-lactamase_39,P62593,1.00935,NO,211,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.896,-4.364,2.468,,0.369,T,A,0.46,-0.69,1.419,,77.62,AHA,-1.94633,0.0495842,0.00648183,1.00935 beta-lactamase_39_G226R,beta-lactamase_39_226,TEM-1,beta-lactamase_39,P62593,1.00935,NO,226,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.461,-3.022,1.561,,0.701,T,l,0.29,-0.25,23.034,23.034,74.48,HOH,-1.42933,0.0495842,0.00665294,1.00935 beta-lactamase_156_P105Y,beta-lactamase_156_105,TEM-1,beta-lactamase_156,P62593,1.00937,NO,105,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.813,-4.385,3.572,,0.226,T,A,0.52,0.8,1.154,,63.29,POH,-1.01533,0.111618,0.0011981,1.00937 beta-lactamase_156_S122N,beta-lactamase_156_122,TEM-1,beta-lactamase_156,P62593,1.00937,NO,122,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.406,-3.042,0.636,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.111618,0.00497825,1.00937 beta-lactamase_2500_A77C,beta-lactamase_2500_77,TEM-1,beta-lactamase_2500,P62593,1.00937,NO,77,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.234,-4.708,3.474,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.361275,0.00282362,1.00937 beta-lactamase_39_P250E,beta-lactamase_39_250,TEM-1,beta-lactamase_39,P62593,1.00937,NO,250,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.0495842,0.00550899,1.00937 beta-lactamase_2500_S122Q,beta-lactamase_2500_122,TEM-1,beta-lactamase_2500,P62593,1.00938,NO,122,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.406,-2.914,0.508,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.361275,0.00497825,1.00938 beta-lactamase_39_R91T,beta-lactamase_39_91,TEM-1,beta-lactamase_39,P62593,1.00938,NO,91,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.392,-2.721,1.329,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.0495842,0.00380226,1.00938 beta-lactamase_156_D99H,beta-lactamase_156_99,TEM-1,beta-lactamase_156,P62593,1.00939,NO,99,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.191,-3.065,1.874,,0.402,G,A,0.75,0.36,3.529,,64.69,PAH,-1.794,0.111618,0.00305446,1.00939 beta-lactamase_0_K109G,beta-lactamase_0_109,TEM-1,beta-lactamase_0,P62593,1.0094,NO,109,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.734,-2.852,1.118,,0.787,G,A,2.34,2.21,15.473,15.473,72.73,ABB,-1.63333,0.0500837,0.00462493,1.0094 beta-lactamase_156_S241C,beta-lactamase_156_241,TEM-1,beta-lactamase_156,P62593,1.0094,NO,241,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.111618,0.00452736,1.0094 beta-lactamase_156_T112P,beta-lactamase_156_112,TEM-1,beta-lactamase_156,P62593,1.0094,NO,112,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.186,-3.939,1.753,,0.921,T,A,0.22,1.06,2.87,,73.78,HPA,-1.925,0.111618,0.00531334,1.0094 beta-lactamase_2500_I258L,beta-lactamase_2500_258,TEM-1,beta-lactamase_2500,P62593,1.00941,NO,258,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.361275,0.007931,1.00941 beta-lactamase_39_E238P,beta-lactamase_39_238,TEM-1,beta-lactamase_39,P62593,1.00941,NO,238,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.0495842,0.00743256,1.00941 beta-lactamase_625_A200V,beta-lactamase_625_200,TEM-1,beta-lactamase_625,P62593,1.00941,NO,200,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.878,-2.943,1.065,,0.757,H,A,0.46,-0.19,12.672,12.672,77.62,HHP,-2.001,0.213352,0.0060056,1.00941 kka2_1:8_R147H,kka2_1:8_147,Kka2,kka2_1:8,P00552,1.00941,NO,147,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.123,-2.32,1.197,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.100394,0.00549168,1.00941 kka2_1:8_R147H,kka2_1:8_147,Kka2,kka2_1:8,P00552,1.00941,NO,147,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.123,-2.32,1.197,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.100394,0.00549168,1.00941 Pab1_T159C,Pab1_159,Pab1,Pab1,P04147,1.00941,NO,159,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.445,-4.604,3.159,,,,,,,2.531,,79.03,HPA,-1.19467,0.175299,0.00133849,1.00941 PSD95pdz3_I389M,PSD95pdz3_389,PSD95pdz3,PSD95pdz3,P31016,1.00941,NO,389,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.628,-3.807,2.179,5.15116,,,,,14.8038,1.498,,87.71,HHH,-1.52167,0.0758425,0.00148097,1.00941 beta-lactamase_156_K30R,beta-lactamase_156_30,TEM-1,beta-lactamase_156,P62593,1.00942,NO,30,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-2.307,-2.265,-0.042,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.111618,0.00448593,1.00942 beta-lactamase_156_T193Q,beta-lactamase_156_193,TEM-1,beta-lactamase_156,P62593,1.00942,NO,193,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.914,-4.169,2.255,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.111618,0.00482669,1.00942 beta-lactamase_625_T178C,beta-lactamase_625_178,TEM-1,beta-lactamase_625,P62593,1.00942,NO,178,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-0.791,-4.637,3.846,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.213352,0.000684366,1.00942 beta-lactamase_39_P143L,beta-lactamase_39_143,TEM-1,beta-lactamase_39,P62593,1.00943,NO,143,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.967,-2.577,1.61,,0.075,H,A,0.52,-0.37,0.976,,66.78,OOB,-1.354,0.0495842,0.00114551,1.00943 Pab1_G167H,Pab1_167,Pab1,Pab1,P04147,1.00943,NO,167,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.223,-4.621,3.398,,0.195,S,g,,0.03,,,,BOH,-1.25133,0.175299,0.00146449,1.00943 beta-lactamase_39_T116V,beta-lactamase_39_116,TEM-1,beta-lactamase_39,P62593,1.00944,NO,116,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.28,-3.415,2.135,,0.115,E,B,0.22,-0.12,1.133,,67.48,HPH,-1.39967,0.0495842,0.00336175,1.00944 PSD95pdz3_I359C,PSD95pdz3_359,PSD95pdz3,PSD95pdz3,P31016,1.00944,NO,359,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.63,-4.319,2.689,5.35151,,,,,14.8012,,,,PHH,-1.58667,0.0758425,0.000580694,1.00944 beta-lactamase_156_D36C,beta-lactamase_156_36,TEM-1,beta-lactamase_156,P62593,1.00945,NO,36,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.732,-5.131,2.399,,0.555,H,A,0.75,1.17,14.871,14.871,77.62,AAP,-1.91167,0.111618,0.00476483,1.00945 beta-lactamase_156_Q88M,beta-lactamase_156_88,TEM-1,beta-lactamase_156,P62593,1.00945,NO,88,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.086,-3.418,1.332,,0.807,,B,0.64,2.03,0.911,,77.62,APH,-1.53433,0.111618,0.00504167,1.00945 beta-lactamase_D250S,beta-lactamase_250,TEM-1,beta-lactamase,P62593,1.00945,NO,250,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.335,-2.842,0.507,5.72026,0.89,T,L,0.23,1.53,24.737,24.737,66.08,OAO,-1.85133,0.221079,0.00550899,1.00945 beta-lactamase_I206V,beta-lactamase_206,TEM-1,beta-lactamase,P62593,1.00946,NO,206,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-2.429,-2.433,0.004,5.3727,0.173,H,A,1,-0.34,2.061,,77.62,HHA,-1.805,0.221079,0.00528934,1.00946 beta-lactamase_Q97K,beta-lactamase_97,TEM-1,beta-lactamase,P62593,1.00946,NO,97,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.072,-2.314,0.242,6.30204,0.823,G,A,1.1,2.42,1.157,,77.62,PPP,-2.43833,0.221079,0.0045116,1.00946 beta-lactamase_39_H24D,beta-lactamase_39_24,TEM-1,beta-lactamase_39,P62593,1.00947,NO,24,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-2.481,-2.42,-0.061,,,,,,,2.708,,93.01,OBO,-2.0035,0.0495842,0.00238894,1.00947 beta-lactamase_39_L137V,beta-lactamase_39_137,TEM-1,beta-lactamase_39,P62593,1.00947,NO,137,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.03,-2.816,1.786,,,H,A,0.55,-0.38,0.674,,42.31,HHP,-1.58933,0.0495842,0.00278599,1.00947 beta-lactamase_A280S,beta-lactamase_280,TEM-1,beta-lactamase,P62593,1.00948,NO,280,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.708,-3.308,1.6,4.74932,0.379,H,A,0.52,-0.72,1.785,,68.18,OHP,-1.66433,0.221079,0.0530888,1.00948 beta-lactamase_G76A,beta-lactamase_76,TEM-1,beta-lactamase,P62593,1.00948,NO,76,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.189,-1.531,0.342,4.73862,,H,A,2.05,-0.67,3.059,,67.83,OOH,-1.22267,0.221079,0.00476637,1.00948 beta-lactamase_39_A182K,beta-lactamase_39_182,TEM-1,beta-lactamase_39,P62593,1.00949,NO,182,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.777,-2.859,1.082,,0.136,H,A,0.46,-0.66,2.598,,93.01,OHH,-1.27367,0.0495842,0.00559099,1.00949 beta-lactamase_R238F,beta-lactamase_238,TEM-1,beta-lactamase,P62593,1.00949,NO,238,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.002,-2.992,0.99,5.87663,0.564,T,L,0.45,1.09,4.195,,72.73,ABO,-1.62633,0.221079,0.00743256,1.00949 PSD95pdz3_V365K,PSD95pdz3_365,PSD95pdz3,PSD95pdz3,P31016,1.00949,NO,365,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.592,-3.363,1.771,5.03791,,,,,18.9657,2.364,,81.35,OHA,-1.288,0.0758425,0.000649764,1.00949 beta-lactamase_156_G243N,beta-lactamase_156_243,TEM-1,beta-lactamase_156,P62593,1.0095,NO,243,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.532,,,,,E,B,0.77,-1.24,2.866,,50,BOH,-1.46867,0.111618,0.00464034,1.0095 beta-lactamase_156_M180I,beta-lactamase_156_180,TEM-1,beta-lactamase_156,P62593,1.0095,NO,180,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-2.795,-3.664,0.869,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.111618,0.00552048,1.0095 beta-lactamase_156_S104G,beta-lactamase_156_104,TEM-1,beta-lactamase_156,P62593,1.0095,NO,104,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.015,-3.017,2.002,,0.04,,b,0.27,0.57,4.02,,63.29,HPO,-1.05267,0.111618,0.00218083,1.0095 beta-lactamase_156_S241E,beta-lactamase_156_241,TEM-1,beta-lactamase_156,P62593,1.0095,NO,241,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.111618,0.00452736,1.0095 beta-lactamase_39_G265V,beta-lactamase_39_265,TEM-1,beta-lactamase_39,P62593,1.0095,NO,265,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.0495842,0.00811926,1.0095 beta-lactamase_39_V157E,beta-lactamase_39_157,TEM-1,beta-lactamase_39,P62593,1.0095,NO,157,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.751,-3.68,1.929,,0.308,S,a,0.44,-0.75,10.364,10.364,69.58,BHP,-2.00767,0.0495842,0.00506849,1.0095 beta-lactamase_39_G226C,beta-lactamase_39_226,TEM-1,beta-lactamase_39,P62593,1.00951,NO,226,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.461,-3.342,1.881,,0.701,T,l,0.29,-0.25,23.034,23.034,74.48,HOH,-1.42933,0.0495842,0.00665294,1.00951 beta-lactamase_39_G76W,beta-lactamase_39_76,TEM-1,beta-lactamase_39,P62593,1.00951,NO,76,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.189,-5.284,4.095,,,H,A,0.29,-0.67,2.145,,67.83,OOH,-1.22267,0.0495842,0.00476637,1.00951 kka2_1:2_E96A,kka2_1:2_96,Kka2,kka2_1:2,P00552,1.00951,NO,96,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.573,-1.097,-1.476,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.295029,0.00369441,1.00951 beta-lactamase_156_T107C,beta-lactamase_156_107,TEM-1,beta-lactamase_156,P62593,1.00952,NO,107,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.117,-4.664,3.547,,,G,A,0.22,-0.06,0.341,,67.83,HPA,-1.265,0.111618,0.00239347,1.00952 beta-lactamase_2500_L196H,beta-lactamase_2500_196,TEM-1,beta-lactamase_2500,P62593,1.00952,NO,196,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-2.478,-3.478,1,,0.518,S,A,0.55,1.35,7.897,,77.62,AHH,-1.839,0.361275,0.00512144,1.00952 beta-lactamase_39_Q267G,beta-lactamase_39_267,TEM-1,beta-lactamase_39,P62593,1.00952,NO,267,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.0495842,0.0102128,1.00952 beta-lactamase_39_V214L,beta-lactamase_39_214,TEM-1,beta-lactamase_39,P62593,1.00952,NO,214,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.299,-2.237,0.938,,0.375,S,A,0.44,-0.44,18.838,18.838,74.48,BHH,-1.53733,0.0495842,0.00628442,1.00952 beta-lactamase_625_A211T,beta-lactamase_625_211,TEM-1,beta-lactamase_625,P62593,1.00952,NO,211,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.896,-2.901,1.005,,0.369,T,A,0.46,-0.69,2.061,,77.62,AHA,-1.94633,0.213352,0.00648183,1.00952 beta-lactamase_156_A84C,beta-lactamase_156_84,TEM-1,beta-lactamase_156,P62593,1.00953,NO,84,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.651,-5.003,3.352,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.111618,0.00503822,1.00953 beta-lactamase_625_Q204H,beta-lactamase_625_204,TEM-1,beta-lactamase_625,P62593,1.00953,NO,204,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-1.382,-3.09,1.708,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.213352,0.00364106,1.00953 beta-lactamase_625_V259L,beta-lactamase_625_259,TEM-1,beta-lactamase_625,P62593,1.00953,NO,259,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.213352,0.0070773,1.00953 gb1_D248K,gb1_248,gb1,gb1,P06654,1.00953,NO,248,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.569,-3.149,1.58,,,,,,,0.344,,11.83,HAH,-1.673,0.177985,0.001865,1.00953 gb1_K236L,gb1_236,gb1,gb1,P06654,1.00953,NO,236,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-2.119,-3.258,1.139,,,,,,,1.083,,45.54,OBP,-1.758,0.177985,0.00255408,1.00953 beta-lactamase_156_E102I,beta-lactamase_156_102,TEM-1,beta-lactamase_156,P62593,1.00954,NO,102,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.118,-4.045,1.927,,0.722,S,B,1.04,1.82,15.721,15.721,73.08,HAH,-1.581,0.111618,0.00486633,1.00954 beta-lactamase_156_R220V,beta-lactamase_156_220,TEM-1,beta-lactamase_156,P62593,1.00954,NO,220,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-0.942,-3.675,2.733,,0.295,I,A,1.2,-0.76,2.164,,74.48,HBP,-1.33633,0.111618,0.00232421,1.00954 beta-lactamase_2500_S96T,beta-lactamase_2500_96,TEM-1,beta-lactamase_2500,P62593,1.00954,NO,96,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.27,-2.436,0.166,,0.368,,b,0.27,0.39,32.348,32.348,73.78,HPP,-2.019,0.361275,0.00551835,1.00954 beta-lactamase_I206A,beta-lactamase_206,TEM-1,beta-lactamase,P62593,1.00954,NO,206,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-2.429,-2.387,-0.042,5.3727,0.173,H,A,1,-0.34,2.061,,77.62,HHA,-1.805,0.221079,0.00528934,1.00954 beta-lactamase_V8H,beta-lactamase_8,TEM-1,beta-lactamase,P62593,1.00954,NO,8,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-2.358,-4.685,2.327,,,,,,,0.575,,77.62,BHH,-2.06267,0.221079,0.00226401,1.00954 kka2_1:8_G95Y,kka2_1:8_95,Kka2,kka2_1:8,P00552,1.00954,NO,95,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-2.403,-4.397,1.994,,0.126,E,B,0.75,-0.74,7.774,,71.59,HOA,-2.198,0.100394,0.00743616,1.00954 kka2_1:8_G95Y,kka2_1:8_95,Kka2,kka2_1:8,P00552,1.00954,NO,95,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-2.403,-4.397,1.994,,0.126,E,B,0.75,-0.74,7.774,,71.59,HOA,-2.198,0.100394,0.00743616,1.00954 beta-lactamase_625_E238N,beta-lactamase_625_238,TEM-1,beta-lactamase_625,P62593,1.00955,NO,238,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.213352,0.00743256,1.00955 beta-lactamase_156_D99F,beta-lactamase_156_99,TEM-1,beta-lactamase_156,P62593,1.00956,NO,99,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.191,-4.277,3.086,,0.402,G,A,0.75,0.36,3.529,,64.69,PAH,-1.794,0.111618,0.00305446,1.00956 beta-lactamase_625_R273S,beta-lactamase_625_273,TEM-1,beta-lactamase_625,P62593,1.00956,NO,273,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.314,-3.326,1.012,,0.564,H,A,1.2,1.57,1.455,,73.78,ABP,-1.841,0.213352,0.0077952,1.00956 beta-lactamase_0_T269L,beta-lactamase_0_269,TEM-1,beta-lactamase_0,P62593,1.00957,NO,269,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.0500837,0.00950944,1.00957 beta-lactamase_156_P105F,beta-lactamase_156_105,TEM-1,beta-lactamase_156,P62593,1.00957,NO,105,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.813,-4.48,3.667,,0.226,T,A,0.52,0.8,1.154,,63.29,POH,-1.01533,0.111618,0.0011981,1.00957 beta-lactamase_156_R63T,beta-lactamase_156_63,TEM-1,beta-lactamase_156,P62593,1.00958,NO,63,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-0.943,-3.447,2.504,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.111618,0.00126938,1.00958 beta-lactamase_625_L89M,beta-lactamase_625_89,TEM-1,beta-lactamase_625,P62593,1.00958,NO,89,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.096,-2.928,1.832,,0.168,T,A,0.55,0.63,1.599,,64.34,PHO,-1.75767,0.213352,0.00207068,1.00958 kka2_1:8_R121G,kka2_1:8_121,Kka2,kka2_1:8,P00552,1.00958,NO,121,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.552,-3.527,1.975,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.100394,0.00523326,1.00958 kka2_1:8_R121G,kka2_1:8_121,Kka2,kka2_1:8,P00552,1.00958,NO,121,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.552,-3.527,1.975,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.100394,0.00523326,1.00958 beta-lactamase_156_P217Q,beta-lactamase_156_217,TEM-1,beta-lactamase_156,P62593,1.00959,NO,217,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-2.062,-3.933,1.871,,0.496,I,A,0.52,-0.33,2.303,,74.48,OOH,-1.64333,0.111618,0.00463211,1.00959 beta-lactamase_39_N130T,beta-lactamase_39_130,TEM-1,beta-lactamase_39,P62593,1.00959,NO,130,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-0.798,-3.196,2.398,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.0495842,0.000683376,1.00959 beta-lactamase_625_A183T,beta-lactamase_625_183,TEM-1,beta-lactamase_625,P62593,1.00959,NO,183,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.231,-3.281,2.05,,0.155,H,A,0.46,-0.91,23.859,23.859,77.62,HHH,-1.53367,0.213352,0.00296631,1.00959 beta-lactamase_39_M66C,beta-lactamase_39_66,TEM-1,beta-lactamase_39,P62593,1.0096,NO,66,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.362,-4.734,3.372,,0.013,,A,0.55,-0.7,1.319,,73.08,OHH,-1.49567,0.0495842,0.00412876,1.0096 beta-lactamase_39_Y44W,beta-lactamase_39_44,TEM-1,beta-lactamase_39,P62593,1.0096,NO,44,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-2.547,-5.1,2.553,,,E,B,0.21,-0.45,2.683,,73.78,OHH,-1.86267,0.0495842,0.00426364,1.0096 beta-lactamase_156_N173S,beta-lactamase_156_173,TEM-1,beta-lactamase_156,P62593,1.00961,NO,173,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-2.663,-3.203,0.54,,1.044,T,l,0.61,1.25,3.718,,77.62,OPA,-1.46633,0.111618,0.0033769,1.00961 beta-lactamase_625_L191I,beta-lactamase_625_191,TEM-1,beta-lactamase_625,P62593,1.00961,NO,191,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.087,-3.028,1.941,,,H,A,0.55,0.09,1.908,,63.29,BHH,-1.445,0.213352,0.00263549,1.00961 beta-lactamase_156_I244F,beta-lactamase_156_244,TEM-1,beta-lactamase_156,P62593,1.00962,NO,244,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.555,-3.842,2.287,,,E,B,0.48,-0.84,1.325,,77.62,OHH,-1.385,0.111618,0.00605379,1.00962 beta-lactamase_156_K286Y,beta-lactamase_156_286,TEM-1,beta-lactamase_156,P62593,1.00963,NO,286,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.111618,,1.00963 beta-lactamase_156_P255D,beta-lactamase_156_255,TEM-1,beta-lactamase_156,P62593,1.00963,NO,255,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.111618,0.00499612,1.00963 beta-lactamase_E166M,beta-lactamase_166,TEM-1,beta-lactamase,P62593,1.00963,NO,166,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.756,-4.707,2.951,5.60527,0.508,G,A,0.52,1.05,2.124,,73.08,OAH,-1.42233,0.221079,0.00512989,1.00963 kka2_1:2_R143I,kka2_1:2_143,Kka2,kka2_1:2,P00552,1.00963,NO,143,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.525,-2.77,0.245,,0.325,H,A,0.16,1.22,14.853,14.853,65.53,ABH,-1.86833,0.295029,0.00662247,1.00963 beta-lactamase_39_K53M,beta-lactamase_39_53,TEM-1,beta-lactamase_39,P62593,1.00964,NO,53,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-2.313,-4.641,2.328,,0.589,,B,2.34,1.15,15.633,15.633,77.62,OBH,-2.1,0.0495842,0.00383383,1.00964 beta-lactamase_625_V29Q,beta-lactamase_625_29,TEM-1,beta-lactamase_625,P62593,1.00964,NO,29,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-2.856,-2.926,0.07,,0.733,H,A,0.44,-0.78,1.931,,93.01,HHB,-2.24733,0.213352,0.00318969,1.00964 beta-lactamase_N50T,beta-lactamase_50,TEM-1,beta-lactamase,P62593,1.00964,NO,50,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-2.979,-2.678,-0.301,5.51261,0.912,T,A,1.07,1.24,1.581,,77.62,HPP,-2.134,0.221079,0.0047211,1.00964 beta-lactamase_156_F58G,beta-lactamase_156_58,TEM-1,beta-lactamase_156,P62593,1.00965,NO,58,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-2.914,-3.566,0.652,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.111618,0.00523369,1.00965 beta-lactamase_625_F70S,beta-lactamase_625_70,TEM-1,beta-lactamase_625,P62593,1.00965,NO,70,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.169,-2.713,1.544,,,H,A,0.58,-1.34,1.14,,63.99,PHB,-0.980667,0.213352,0.00193499,1.00965 beta-lactamase_625_S122E,beta-lactamase_625_122,TEM-1,beta-lactamase_625,P62593,1.00965,NO,122,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.406,-2.103,-0.303,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.213352,0.00497825,1.00965 beta-lactamase_Q97P,beta-lactamase_97,TEM-1,beta-lactamase,P62593,1.00965,NO,97,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.072,-2.583,0.511,6.30204,0.823,G,A,1.1,2.42,1.157,,77.62,PPP,-2.43833,0.221079,0.0045116,1.00965 beta-lactamase_156_V29R,beta-lactamase_156_29,TEM-1,beta-lactamase_156,P62593,1.00966,NO,29,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-2.856,-3.682,0.826,,0.733,H,A,0.44,-0.78,3.685,,93.01,HHB,-2.24733,0.111618,0.00318969,1.00966 beta-lactamase_39_G194A,beta-lactamase_39_194,TEM-1,beta-lactamase_39,P62593,1.00966,NO,194,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.396,-2.558,1.162,,0.276,S,b,0.29,0.36,4.852,,67.83,POA,-1.832,0.0495842,0.00392163,1.00966 beta-lactamase_156_G226F,beta-lactamase_156_226,TEM-1,beta-lactamase_156,P62593,1.00967,NO,226,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.461,-4.428,2.967,,0.701,T,l,0.29,-0.25,3.199,,74.48,HOH,-1.42933,0.111618,0.00665294,1.00967 beta-lactamase_156_L100W,beta-lactamase_156_100,TEM-1,beta-lactamase_156,P62593,1.00967,NO,100,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.218,-5.168,3.95,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.111618,0.00413885,1.00967 beta-lactamase_39_L49N,beta-lactamase_39_49,TEM-1,beta-lactamase_39,P62593,1.00967,NO,49,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.897,-3.842,1.945,,0.131,T,A,0.55,0.04,13.838,13.838,64.69,AHP,-1.99233,0.0495842,0.00401477,1.00967 beta-lactamase_39_K190H,beta-lactamase_39_190,TEM-1,beta-lactamase_39,P62593,1.00968,NO,190,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.994,-3.068,1.074,,0.371,H,A,2.34,0.16,1.513,,77.62,BBH,-1.64167,0.0495842,0.00574527,1.00968 beta-lactamase_39_L47V,beta-lactamase_39_47,TEM-1,beta-lactamase_39,P62593,1.00968,NO,47,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.876,-2.564,0.688,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.0495842,0.00439844,1.00968 beta-lactamase_625_A148Q,beta-lactamase_625_148,TEM-1,beta-lactamase_625,P62593,1.00968,NO,148,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.757,-3.083,1.326,,0.379,H,A,0.46,-0.55,1.359,,72.73,PHH,-1.40167,0.213352,0.00547053,1.00968 beta-lactamase_D212D,beta-lactamase_212,TEM-1,beta-lactamase,P62593,1.00968,NO,212,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.624,-1.624,,4.9705,0.037,,b,1.3,-0.58,12.482,,74.48,HAB,-1.77667,0.221079,0.00644302,1.00968 gb1_A246V,gb1_246,gb1,gb1,P06654,1.00968,NO,246,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.175,-2.814,1.639,,,,,,,,,,AHH,-1.87033,0.177985,0.00190625,1.00968 beta-lactamase_156_S51V,beta-lactamase_156_51,TEM-1,beta-lactamase_156,P62593,1.00969,NO,51,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.526,-3.559,2.033,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.111618,0.00504821,1.00969 kka2_1:4_M148A,kka2_1:4_148,Kka2,kka2_1:4,P00552,1.0097,NO,148,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.847,-2.283,0.436,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.168804,0.00982664,1.0097 beta-lactamase_156_N173R,beta-lactamase_156_173,TEM-1,beta-lactamase_156,P62593,1.00971,NO,173,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-2.663,-3.837,1.174,,1.044,T,l,0.61,1.25,3.718,,77.62,OPA,-1.46633,0.111618,0.0033769,1.00971 beta-lactamase_625_N152R,beta-lactamase_625_152,TEM-1,beta-lactamase_625,P62593,1.00971,NO,152,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-2.757,-2.835,0.078,,0.863,H,A,0.61,0.92,2.061,,77.62,BPH,-2.97,0.213352,0.00471429,1.00971 beta-lactamase_156_R92H,beta-lactamase_156_92,TEM-1,beta-lactamase_156,P62593,1.00972,NO,92,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.718,-4.618,2.9,,0.479,E,B,1.2,1.36,19.112,19.112,65.38,BBH,-1.50367,0.111618,0.00429626,1.00972 beta-lactamase_625_A282C,beta-lactamase_625_282,TEM-1,beta-lactamase_625,P62593,1.00972,NO,282,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.213352,0.0449821,1.00972 PSD95pdz3_I341M,PSD95pdz3_341,PSD95pdz3,PSD95pdz3,P31016,1.00972,NO,341,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.63,-3.712,2.082,5.73946,,,,,10.3187,,,,HHH,-1.50033,0.0758425,0.000824087,1.00972 beta-lactamase_156_T27V,beta-lactamase_156_27,TEM-1,beta-lactamase_156,P62593,1.00973,NO,27,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.905,-3.409,1.504,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.111618,0.00306559,1.00973 E1_Ubiquitin_F45G,E1_Ubiquitin_45,Uba1,E1_Ubiquitin,P0CG63,1.00973,NO,45,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.149,-3.4,2.251,,0.26,E,B,,-0.99,,,,HHH,-1.316,0.18783,0.00193245,1.00973 E1_Ubiquitin_L43W,E1_Ubiquitin_43,Uba1,E1_Ubiquitin,P0CG63,1.00973,NO,43,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.188,-4.968,3.78,,,E,B,,-1.17,,,,BHH,-1.30733,0.18783,0.00190185,1.00973 E1_Ubiquitin_L73L,E1_Ubiquitin_73,Uba1,E1_Ubiquitin,P0CG63,1.00973,NO,73,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.039,-1.039,,,0.518,,B,1.3,1,,,,BHB,-1.175,0.18783,0.00111236,1.00973 E1_Ubiquitin_R42P,E1_Ubiquitin_42,Uba1,E1_Ubiquitin,P0CG63,1.00973,NO,42,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.302,-3.69,2.388,,0.244,E,B,,-0.54,,,,PBH,-1.24667,0.18783,0.00224033,1.00973 kka2_1:8_G55P,kka2_1:8_55,Kka2,kka2_1:8,P00552,1.00974,NO,55,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.625,-4.068,2.443,,0.517,S,b,0.29,1.19,8.881,,63.64,POH,-2.05967,0.100394,0.00667877,1.00974 kka2_1:8_G55P,kka2_1:8_55,Kka2,kka2_1:8,P00552,1.00974,NO,55,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.625,-4.068,2.443,,0.517,S,b,0.29,1.19,8.881,,63.64,POH,-2.05967,0.100394,0.00667877,1.00974 Pab1_V148L,Pab1_148,Pab1,Pab1,P04147,1.00974,NO,148,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.875,-2.985,1.11,,,,,,,,,,PHH,-1.43033,0.175299,0.00179641,1.00974 beta-lactamase_39_G265Q,beta-lactamase_39_265,TEM-1,beta-lactamase_39,P62593,1.00975,NO,265,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-2.58,-2.659,0.079,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.0495842,0.00811926,1.00975 beta-lactamase_39_T112Y,beta-lactamase_39_112,TEM-1,beta-lactamase_39,P62593,1.00976,NO,112,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.186,-4.422,2.236,,0.921,T,A,0.22,1.06,2.87,,73.78,HPA,-1.925,0.0495842,0.00531334,1.00976 beta-lactamase_39_E46R,beta-lactamase_39_46,TEM-1,beta-lactamase_39,P62593,1.00977,NO,46,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.94,-4.04,2.1,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.0495842,0.00427568,1.00977 beta-lactamase_39_L135G,beta-lactamase_39_135,TEM-1,beta-lactamase_39,P62593,1.00978,NO,135,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.002,-3.837,2.835,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.0495842,0.00244423,1.00978 beta-lactamase_156_Y44M,beta-lactamase_156_44,TEM-1,beta-lactamase_156,P62593,1.00979,NO,44,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-2.547,-2.521,-0.026,,,E,B,0.21,-0.45,2.184,,73.78,OHH,-1.86267,0.111618,0.00426364,1.00979 beta-lactamase_625_L150A,beta-lactamase_625_150,TEM-1,beta-lactamase_625,P62593,1.00979,NO,150,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.326,-2.051,0.725,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.213352,0.00463171,1.00979 beta-lactamase_625_P25I,beta-lactamase_625_25,TEM-1,beta-lactamase_625,P62593,1.00979,NO,25,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.526,-4.029,2.503,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.213352,0.00347571,1.00979 Pab1_D144E,Pab1_144,Pab1,Pab1,P04147,1.0098,NO,144,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.189,-1.748,0.559,,0.616,H,A,,0.6,,,,HAP,-1.40567,0.175299,0.00121131,1.0098 PSD95pdz3_I388L,PSD95pdz3_388,PSD95pdz3,PSD95pdz3,P31016,1.0098,NO,388,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.63,-2.14,0.51,5.17282,,,,,16.0025,,,,PHH,-1.54967,0.0758425,0.000151216,1.0098 beta-lactamase_39_Q88S,beta-lactamase_39_88,TEM-1,beta-lactamase_39,P62593,1.00981,NO,88,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.086,-2.48,0.394,,0.807,,B,0.64,2.03,11.108,11.108,77.62,APH,-1.53433,0.0495842,0.00504167,1.00981 beta-lactamase_625_A84H,beta-lactamase_625_84,TEM-1,beta-lactamase_625,P62593,1.00981,NO,84,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.651,-3.344,1.693,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.213352,0.00503822,1.00981 beta-lactamase_156_F149I,beta-lactamase_156_149,TEM-1,beta-lactamase_156,P62593,1.00982,NO,149,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.299,-3.576,2.277,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.111618,0.00418462,1.00982 beta-lactamase_625_E210C,beta-lactamase_625_210,TEM-1,beta-lactamase_625,P62593,1.00982,NO,210,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.319,-4.991,2.672,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.213352,0.00663582,1.00982 beta-lactamase_625_Y95M,beta-lactamase_625_95,TEM-1,beta-lactamase_625,P62593,1.00982,NO,95,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-1.715,-4.404,2.689,,0.122,,b,0.21,-0.37,3.355,,77.62,BHP,-2.16167,0.213352,0.00479449,1.00982 beta-lactamase_L111V,beta-lactamase_111,TEM-1,beta-lactamase,P62593,1.00982,NO,111,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.76,-1.731,-0.029,5.8705,0.328,T,A,0.84,0.93,3.836,,64.34,BHP,-1.884,0.221079,0.00480671,1.00982 beta-lactamase_L191M,beta-lactamase_191,TEM-1,beta-lactamase,P62593,1.00982,NO,191,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.087,-4.016,2.929,5.72226,,H,A,1.07,0.09,1.23,,63.29,BHH,-1.445,0.221079,0.00263549,1.00982 beta-lactamase_N173C,beta-lactamase_173,TEM-1,beta-lactamase,P62593,1.00982,NO,173,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-2.663,-5.092,2.429,7.02497,1.044,T,l,0.09,1.25,1.88,,77.62,OPA,-1.46633,0.221079,0.0033769,1.00982 beta-lactamase_R81K,beta-lactamase_81,TEM-1,beta-lactamase,P62593,1.00982,NO,81,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.466,-2.393,0.927,5.12166,0.218,H,A,0.68,1.66,1.236,,50,PBH,-1.60667,0.221079,0.00499763,1.00982 PSD95pdz3_Q384R,PSD95pdz3_384,PSD95pdz3,PSD95pdz3,P31016,1.00982,NO,384,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-1.699,-2.94,1.241,5.49339,,,,,23.54,,,,OPP,-1.41333,0.0758425,0.000216736,1.00982 beta-lactamase_625_I54E,beta-lactamase_625_54,TEM-1,beta-lactamase_625,P62593,1.00983,NO,54,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-2.838,-2.58,-0.258,,0.669,E,B,0.48,-0.14,3.946,,73.78,BHH,-2.337,0.213352,0.00403589,1.00983 beta-lactamase_625_P255S,beta-lactamase_625_255,TEM-1,beta-lactamase_625,P62593,1.00983,NO,255,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.213352,0.00499612,1.00983 kka2_1:2_V46I,kka2_1:2_46,Kka2,kka2_1:2,P00552,1.00983,NO,46,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-2.62,-3.923,1.303,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.295029,0.00631301,1.00983 beta-lactamase_156_N152M,beta-lactamase_156_152,TEM-1,beta-lactamase_156,P62593,1.00984,NO,152,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-2.757,-4.737,1.98,,0.863,H,A,0.61,0.92,4.038,,77.62,BPH,-2.97,0.111618,0.00471429,1.00984 beta-lactamase_2500_A148M,beta-lactamase_2500_148,TEM-1,beta-lactamase_2500,P62593,1.00984,NO,148,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.757,-4.798,3.041,,0.379,H,A,0.46,-0.55,2.117,,72.73,PHH,-1.40167,0.361275,0.00547053,1.00984 beta-lactamase_39_I54K,beta-lactamase_39_54,TEM-1,beta-lactamase_39,P62593,1.00984,NO,54,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-2.838,-2.926,0.088,,0.669,E,B,0.48,-0.14,1.349,,73.78,BHH,-2.337,0.0495842,0.00403589,1.00984 beta-lactamase_625_T139D,beta-lactamase_625_139,TEM-1,beta-lactamase_625,P62593,1.00984,NO,139,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.901,-3.596,1.695,,0.216,H,A,0.22,0.39,2.256,,77.62,PPH,-2.04667,0.213352,0.00441837,1.00984 beta-lactamase_156_E145K,beta-lactamase_156_145,TEM-1,beta-lactamase_156,P62593,1.00985,NO,145,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.357,-3.472,1.115,,0.545,H,A,1.04,0.79,3.661,,77.62,BAH,-2.069,0.111618,0.00553285,1.00985 beta-lactamase_625_Q88H,beta-lactamase_625_88,TEM-1,beta-lactamase_625,P62593,1.00985,NO,88,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.086,-4.599,2.513,,0.807,,B,0.64,2.03,1.84,,77.62,APH,-1.53433,0.213352,0.00504167,1.00985 beta-lactamase_L160V,beta-lactamase_160,TEM-1,beta-lactamase,P62593,1.00986,NO,160,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.977,-2.271,1.294,5.32068,0.022,,B,1.75,-0.6,0.895,,44.41,BHA,-0.936,0.221079,0.00193775,1.00986 beta-lactamase_Y44Y,beta-lactamase_44,TEM-1,beta-lactamase,P62593,1.00986,NO,44,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-2.547,-2.547,,5.6273,,E,B,2.55,-0.45,2.683,,73.78,OHH,-1.86267,0.221079,0.00426364,1.00986 beta-lactamase_156_D271Q,beta-lactamase_156_271,TEM-1,beta-lactamase_156,P62593,1.00987,NO,271,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.111618,0.00752082,1.00987 beta-lactamase_39_H151F,beta-lactamase_39_151,TEM-1,beta-lactamase_39,P62593,1.00987,NO,151,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-2.96,-4.308,1.348,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.0495842,0.00216946,1.00987 beta-lactamase_625_E87S,beta-lactamase_625_87,TEM-1,beta-lactamase_625,P62593,1.00987,NO,87,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.421,-3.382,1.961,,0.048,,B,1.04,0.92,17.923,17.923,64.69,PAP,-1.969,0.213352,0.00337888,1.00987 beta-lactamase_625_L38E,beta-lactamase_625_38,TEM-1,beta-lactamase_625,P62593,1.00987,NO,38,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.343,-3.797,2.454,,0.088,H,A,0.55,0.2,1.986,,64.34,PHO,-1.78033,0.213352,0.00373244,1.00987 beta-lactamase_156_E272K,beta-lactamase_156_272,TEM-1,beta-lactamase_156,P62593,1.00988,NO,272,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.111618,0.00545371,1.00988 beta-lactamase_39_T131P,beta-lactamase_39_131,TEM-1,beta-lactamase_39,P62593,1.00988,NO,131,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.328,-3.82,2.492,,,H,A,0.22,-0.69,3.306,,67.48,PPH,-1.00867,0.0495842,0.00345886,1.00988 beta-lactamase_625_E210S,beta-lactamase_625_210,TEM-1,beta-lactamase_625,P62593,1.00988,NO,210,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.319,-2.669,0.35,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.213352,0.00663582,1.00988 beta-lactamase_39_G76V,beta-lactamase_39_76,TEM-1,beta-lactamase_39,P62593,1.00989,NO,76,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.189,-3.485,2.296,,,H,A,0.29,-0.67,2.145,,67.83,OOH,-1.22267,0.0495842,0.00476637,1.00989 beta-lactamase_156_R41F,beta-lactamase_156_41,TEM-1,beta-lactamase_156,P62593,1.0099,NO,41,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-0.942,-4.29,3.348,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.111618,0.00123327,1.0099 beta-lactamase_39_P60V,beta-lactamase_39_60,TEM-1,beta-lactamase_39,P62593,1.0099,NO,60,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-2.469,-3.507,1.038,,0.256,T,A,0.52,-0.56,21.37,21.37,77.62,BOA,-1.97633,0.0495842,0.00521318,1.0099 beta-lactamase_625_A84S,beta-lactamase_625_84,TEM-1,beta-lactamase_625,P62593,1.0099,NO,84,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.651,-2.609,0.958,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.213352,0.00503822,1.0099 hsp90_Q582R,hsp90_582,hsp90,hsp90,P02829,1.0099,NO,582,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-3.278,-3.086,0,4.91603,0.453,S,B,,0.67,,,,OPH,-3.249,0.368192,0.000222939,1.0099 beta-lactamase_625_A124M,beta-lactamase_625_124,TEM-1,beta-lactamase_625,P62593,1.00991,NO,124,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.181,-4.519,3.338,,,H,A,0.46,-0.9,2.027,,64.34,HHH,-1.152,0.213352,0.00481399,1.00991 beta-lactamase_625_E210V,beta-lactamase_625_210,TEM-1,beta-lactamase_625,P62593,1.00991,NO,210,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.319,-1.881,-0.438,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.213352,0.00663582,1.00991 beta-lactamase_Q88A,beta-lactamase_88,TEM-1,beta-lactamase,P62593,1.00991,NO,88,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.086,-2.75,0.664,5.8056,0.807,,B,0.12,2.03,1.84,,77.62,APH,-1.53433,0.221079,0.00504167,1.00991 kka2_1:1_S11G,kka2_1:1_11,Kka2,kka2_1:1,P00552,1.00991,NO,11,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.322,-3.427,1.105,,0.408,,B,0.77,1.64,2.054,,92.05,OPO,-1.69867,0.520039,0.00381691,1.00991 beta-lactamase_156_E61C,beta-lactamase_156_61,TEM-1,beta-lactamase_156,P62593,1.00992,NO,61,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.115,-5.186,3.071,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.111618,0.00440955,1.00992 beta-lactamase_39_V214F,beta-lactamase_39_214,TEM-1,beta-lactamase_39,P62593,1.00992,NO,214,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.299,-3.997,2.698,,0.375,S,A,0.44,-0.44,18.838,18.838,74.48,BHH,-1.53733,0.0495842,0.00628442,1.00992 beta-lactamase_625_F64Y,beta-lactamase_625_64,TEM-1,beta-lactamase_625,P62593,1.00993,NO,64,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-0.841,-3.037,2.196,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.213352,0.000947691,1.00993 beta-lactamase_0_L192H,beta-lactamase_0_192,TEM-1,beta-lactamase_0,P62593,1.00994,NO,192,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.254,-4.926,3.672,,0.095,H,A,0.55,0.35,1.756,,60.14,HHP,-1.41833,0.0500837,0.00558728,1.00994 beta-lactamase_156_G216I,beta-lactamase_156_216,TEM-1,beta-lactamase_156,P62593,1.00995,NO,216,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.477,-4.183,2.706,,0.437,I,A,0.29,-0.58,12.464,12.464,74.48,HOO,-1.68067,0.111618,0.00639568,1.00995 beta-lactamase_156_V117L,beta-lactamase_156_117,TEM-1,beta-lactamase_156,P62593,1.00995,NO,117,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.53,-1.606,0.076,,,H,A,0.44,-0.34,1.182,,65.03,PHB,-1.741,0.111618,0.00467906,1.00995 beta-lactamase_156_Y103M,beta-lactamase_156_103,TEM-1,beta-lactamase_156,P62593,1.00995,NO,103,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-1.33,-4.627,3.297,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.111618,0.00443048,1.00995 beta-lactamase_39_L49C,beta-lactamase_39_49,TEM-1,beta-lactamase_39,P62593,1.00995,NO,49,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.897,-4.929,3.032,,0.131,T,A,0.55,0.04,13.838,13.838,64.69,AHP,-1.99233,0.0495842,0.00401477,1.00995 beta-lactamase_625_A282D,beta-lactamase_625_282,TEM-1,beta-lactamase_625,P62593,1.00995,NO,282,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.213352,0.0449821,1.00995 beta-lactamase_156_L150Y,beta-lactamase_156_150,TEM-1,beta-lactamase_156,P62593,1.00996,NO,150,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.326,-4.133,2.807,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.111618,0.00463171,1.00996 beta-lactamase_39_G114A,beta-lactamase_39_114,TEM-1,beta-lactamase_39,P62593,1.00996,NO,114,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.094,-2.444,1.35,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.0495842,0.00224919,1.00996 beta-lactamase_39_L89I,beta-lactamase_39_89,TEM-1,beta-lactamase_39,P62593,1.00996,NO,89,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.096,-3.166,2.07,,0.168,T,A,0.55,0.63,3.233,,64.34,PHO,-1.75767,0.0495842,0.00207068,1.00996 beta-lactamase_K252V,beta-lactamase_252,TEM-1,beta-lactamase,P62593,1.00997,NO,252,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.94,-3.835,1.895,5.56823,0.766,,B,1.82,1.16,21.796,21.796,67.83,OBO,-2.03333,0.221079,0.00575769,1.00997 beta-lactamase_156_K190Q,beta-lactamase_156_190,TEM-1,beta-lactamase_156,P62593,1.00998,NO,190,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.994,-2.883,0.889,,0.371,H,A,2.34,0.16,1.513,,77.62,BBH,-1.64167,0.111618,0.00574527,1.00998 beta-lactamase_625_K254N,beta-lactamase_625_254,TEM-1,beta-lactamase_625,P62593,1.00998,NO,254,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.213352,0.00369,1.00998 kka2_1:4_K138S,kka2_1:4_138,Kka2,kka2_1:4,P00552,1.00998,NO,138,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-2.5,-2.62,0.12,,0.594,H,A,1.3,0.98,21.267,21.267,71.59,HBB,-2.48833,0.168804,0.00628542,1.00998 beta-lactamase_156_H24M,beta-lactamase_156_24,TEM-1,beta-lactamase_156,P62593,1.00999,NO,24,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-2.481,-3.144,0.663,,,,,,,2.708,,93.01,OBO,-2.0035,0.111618,0.00238894,1.00999 beta-lactamase_625_E166H,beta-lactamase_625_166,TEM-1,beta-lactamase_625,P62593,1.00999,NO,166,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.756,-4.668,2.912,,0.508,G,A,1.04,1.05,2.124,,73.08,OAH,-1.42233,0.213352,0.00512989,1.00999 beta-lactamase_625_L284C,beta-lactamase_625_284,TEM-1,beta-lactamase_625,P62593,1.00999,NO,284,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.213352,0.0686156,1.00999 PSD95pdz3_A378S,PSD95pdz3_378,PSD95pdz3,PSD95pdz3,P31016,1.00999,NO,378,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.307,-2.617,1.31,4.86582,,,,,14.576,,,,HHH,-1.509,0.0758425,0.000313169,1.00999 PSD95pdz3_S350L,PSD95pdz3_350,PSD95pdz3,PSD95pdz3,P31016,1.00999,NO,350,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.519,-3.04,1.521,4.97629,,,,,25.01,,,,HPO,-1.29133,0.0758425,0.000704883,1.00999 kka2_1:8_L107H,kka2_1:8_107,Kka2,kka2_1:8,P00552,1.01,NO,107,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.238,-4.994,3.756,,0.197,.,B,0.55,-1.1,4.478,,71.59,BHH,-2.143,0.100394,0.00561937,1.01 kka2_1:8_L107H,kka2_1:8_107,Kka2,kka2_1:8,P00552,1.01,NO,107,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.238,-4.994,3.756,,0.197,.,B,0.55,-1.1,4.478,,71.59,BHH,-2.143,0.100394,0.00561937,1.01 beta-lactamase_156_E87Y,beta-lactamase_156_87,TEM-1,beta-lactamase_156,P62593,1.01001,NO,87,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.421,-4.262,2.841,,0.048,,B,1.04,0.92,1.754,,64.69,PAP,-1.969,0.111618,0.00337888,1.01001 beta-lactamase_625_L28A,beta-lactamase_625_28,TEM-1,beta-lactamase_625,P62593,1.01001,NO,28,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.579,-2.126,0.547,,0.277,H,A,0.55,-0.16,2.716,,93.01,PHH,-2.11333,0.213352,0.00359321,1.01001 beta-lactamase_625_A124G,beta-lactamase_625_124,TEM-1,beta-lactamase_625,P62593,1.01002,NO,124,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.181,-3.186,2.005,,,H,A,0.46,-0.9,2.027,,64.34,HHH,-1.152,0.213352,0.00481399,1.01002 beta-lactamase_A16C,beta-lactamase_16,TEM-1,beta-lactamase,P62593,1.01002,NO,16,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,,-4.853,2.918,,,,,,,,,,HHH,,0.221079,0.00245392,1.01002 beta-lactamase_A211E,beta-lactamase_211,TEM-1,beta-lactamase,P62593,1.01002,NO,211,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.896,-2.447,0.551,5.54662,0.369,T,A,0.52,-0.69,2.061,,77.62,AHA,-1.94633,0.221079,0.00648183,1.01002 beta-lactamase_E169S,beta-lactamase_169,TEM-1,beta-lactamase,P62593,1.01002,NO,169,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.23,-2.21,0.98,5.78896,0.337,,A,0.52,1,1.806,,73.08,PAH,-1.16533,0.221079,0.00400994,1.01002 beta-lactamase_T112P,beta-lactamase_112,TEM-1,beta-lactamase,P62593,1.01002,NO,112,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.186,-3.939,1.753,6.47162,0.921,T,A,0.77,1.06,2.04,,73.78,HPA,-1.925,0.221079,0.00531334,1.01002 beta-lactamase_V29D,beta-lactamase_29,TEM-1,beta-lactamase,P62593,1.01002,NO,29,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-2.856,-2.298,-0.558,5.58481,0.733,H,A,0.23,-0.78,1.287,,93.01,HHB,-2.24733,0.221079,0.00318969,1.01002 beta-lactamase_V29E,beta-lactamase_29,TEM-1,beta-lactamase,P62593,1.01002,NO,29,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-2.856,-1.855,-1.001,5.58481,0.733,H,A,0.23,-0.78,1.287,,93.01,HHB,-2.24733,0.221079,0.00318969,1.01002 beta-lactamase_2500_S221R,beta-lactamase_2500_221,TEM-1,beta-lactamase_2500,P62593,1.01003,NO,221,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.754,-2.83,1.076,,0.624,H,A,0.27,-0.2,1.971,,74.48,BPH,-1.59967,0.361275,0.0046094,1.01003 kka2_1:8_A237C,kka2_1:8_237,Kka2,kka2_1:8,P00552,1.01003,NO,237,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.12,-4.796,2.676,,0.068,H,A,0.46,-0.71,0.449,,92.05,HHA,-2.10433,0.100394,0.012257,1.01003 kka2_1:8_A237C,kka2_1:8_237,Kka2,kka2_1:8,P00552,1.01003,NO,237,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.12,-4.796,2.676,,0.068,H,A,0.46,-0.71,0.449,,92.05,HHA,-2.10433,0.100394,0.012257,1.01003 kka2_1:8_S104K,kka2_1:8_104,Kka2,kka2_1:8,P00552,1.01003,NO,104,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.436,-3.48,2.044,,0.536,T,A,0.27,-1.11,1.689,,63.64,HPP,-1.91433,0.100394,0.00555207,1.01003 kka2_1:8_S104K,kka2_1:8_104,Kka2,kka2_1:8,P00552,1.01003,NO,104,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.436,-3.48,2.044,,0.536,T,A,0.27,-1.11,1.689,,63.64,HPP,-1.91433,0.100394,0.00555207,1.01003 beta-lactamase_39_R273G,beta-lactamase_39_273,TEM-1,beta-lactamase_39,P62593,1.01004,NO,273,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.314,-2.465,0.151,,0.564,H,A,1.2,1.57,2.163,,73.78,ABP,-1.841,0.0495842,0.0077952,1.01004 beta-lactamase_39_R273L,beta-lactamase_39_273,TEM-1,beta-lactamase_39,P62593,1.01005,NO,273,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.314,-3.556,1.242,,0.564,H,A,1.2,1.57,2.163,,73.78,ABP,-1.841,0.0495842,0.0077952,1.01005 beta-lactamase_625_E166K,beta-lactamase_625_166,TEM-1,beta-lactamase_625,P62593,1.01005,NO,166,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.756,-2.625,0.869,,0.508,G,A,1.04,1.05,2.124,,73.08,OAH,-1.42233,0.213352,0.00512989,1.01005 beta-lactamase_156_K53F,beta-lactamase_156_53,TEM-1,beta-lactamase_156,P62593,1.01006,NO,53,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-2.313,-4.249,1.936,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.111618,0.00383383,1.01006 beta-lactamase_156_T139D,beta-lactamase_156_139,TEM-1,beta-lactamase_156,P62593,1.01006,NO,139,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.901,-3.596,1.695,,0.216,H,A,0.22,0.39,16.34,16.34,77.62,PPH,-2.04667,0.111618,0.00441837,1.01006 beta-lactamase_39_I45N,beta-lactamase_39_45,TEM-1,beta-lactamase_39,P62593,1.01006,NO,45,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-2.421,-3.135,0.714,,,E,B,0.48,-0.3,2.256,,77.62,HHA,-2.30267,0.0495842,0.00452842,1.01006 beta-lactamase_A148G,beta-lactamase_148,TEM-1,beta-lactamase,P62593,1.01006,NO,148,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.757,-2.542,0.785,5.28111,0.379,H,A,0.52,-0.55,2.117,,72.73,PHH,-1.40167,0.221079,0.00547053,1.01006 beta-lactamase_39_F228C,beta-lactamase_39_228,TEM-1,beta-lactamase_39,P62593,1.01007,NO,228,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-2.342,-5.075,2.733,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.0495842,0.0046669,1.01007 beta-lactamase_39_K190D,beta-lactamase_39_190,TEM-1,beta-lactamase_39,P62593,1.01007,NO,190,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.994,-3.691,1.697,,0.371,H,A,2.34,0.16,1.513,,77.62,BBH,-1.64167,0.0495842,0.00574527,1.01007 beta-lactamase_39_P60H,beta-lactamase_39_60,TEM-1,beta-lactamase_39,P62593,1.01007,NO,60,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-2.469,-3.266,0.797,,0.256,T,A,0.52,-0.56,21.37,21.37,77.62,BOA,-1.97633,0.0495842,0.00521318,1.01007 beta-lactamase_625_N152S,beta-lactamase_625_152,TEM-1,beta-lactamase_625,P62593,1.01007,NO,152,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-2.757,-1.988,-0.769,,0.863,H,A,0.61,0.92,2.061,,77.62,BPH,-2.97,0.213352,0.00471429,1.01007 beta-lactamase_625_N50C,beta-lactamase_625_50,TEM-1,beta-lactamase_625,P62593,1.01007,NO,50,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-2.979,-5.044,2.065,,0.912,T,A,0.61,1.24,3.446,,77.62,HPP,-2.134,0.213352,0.0047211,1.01007 beta-lactamase_156_R176I,beta-lactamase_156_176,TEM-1,beta-lactamase_156,P62593,1.01008,NO,176,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-0.863,-4.01,3.147,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.111618,0.00105554,1.01008 beta-lactamase_39_A222M,beta-lactamase_39_222,TEM-1,beta-lactamase_39,P62593,1.01008,NO,222,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.103,-4.656,2.553,,0.233,H,A,0.46,-0.25,1.448,,77.62,PHH,-1.63733,0.0495842,0.00466094,1.01008 beta-lactamase_39_G43A,beta-lactamase_39_43,TEM-1,beta-lactamase_39,P62593,1.01008,NO,43,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.62,-2.853,2.233,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.0495842,0.00120151,1.01008 beta-lactamase_39_R159A,beta-lactamase_39_159,TEM-1,beta-lactamase_39,P62593,1.01008,NO,159,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-0.94,-3.127,2.187,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.0495842,0.00108472,1.01008 beta-lactamase_625_E26D,beta-lactamase_625_26,TEM-1,beta-lactamase_625,P62593,1.01008,NO,26,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.454,-2.507,0.053,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.213352,0.00297948,1.01008 beta-lactamase_39_S104A,beta-lactamase_39_104,TEM-1,beta-lactamase_39,P62593,1.01009,NO,104,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.015,-2.043,1.028,,0.04,,b,0.27,0.57,4.02,,63.29,HPO,-1.05267,0.0495842,0.00218083,1.01009 beta-lactamase_625_G39W,beta-lactamase_625_39,TEM-1,beta-lactamase_625,P62593,1.01009,NO,39,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.864,-5.517,3.653,,0.701,T,L,0.29,0.47,29.926,29.926,77.62,HOH,-1.53633,0.213352,0.00487611,1.01009 beta-lactamase_625_H94Q,beta-lactamase_625_94,TEM-1,beta-lactamase_625,P62593,1.01009,NO,94,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-2.5,-3.155,0.655,,0.776,,B,0.17,1.24,19.42,19.42,77.62,HBH,-1.872,0.213352,0.00389226,1.01009 beta-lactamase_39_A230F,beta-lactamase_39_230,TEM-1,beta-lactamase_39,P62593,1.0101,NO,230,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.154,-4.217,3.063,,0.01,E,B,0.46,-1.17,1.171,,50,HHA,-1.079,0.0495842,0.00516841,1.0101 beta-lactamase_156_W208A,beta-lactamase_156_208,TEM-1,beta-lactamase_156,P62593,1.01011,NO,208,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-0.818,-3.528,2.71,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.111618,0.00126609,1.01011 beta-lactamase_2500_R189F,beta-lactamase_2500_189,TEM-1,beta-lactamase_2500,P62593,1.01011,NO,189,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.844,-4.275,2.431,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.361275,0.0050699,1.01011 beta-lactamase_39_K53N,beta-lactamase_39_53,TEM-1,beta-lactamase_39,P62593,1.01011,NO,53,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-2.313,-3.809,1.496,,0.589,,B,2.34,1.15,15.633,15.633,77.62,OBH,-2.1,0.0495842,0.00383383,1.01011 beta-lactamase_625_E119G,beta-lactamase_625_119,TEM-1,beta-lactamase_625,P62593,1.01011,NO,119,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.412,-2.405,0.993,,0.358,H,A,1.04,0.51,1.034,,63.99,BAH,-1.623,0.213352,0.00386966,1.01011 beta-lactamase_625_T112F,beta-lactamase_625_112,TEM-1,beta-lactamase_625,P62593,1.01011,NO,112,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.186,-4.382,2.196,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.213352,0.00531334,1.01011 beta-lactamase_Q86Q,beta-lactamase_86,TEM-1,beta-lactamase,P62593,1.01011,NO,86,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.4,-2.4,,5.39897,0.696,S,A,0.12,2.38,2.105,,77.62,OPA,-1.61067,0.221079,0.00450027,1.01011 beta-lactamase_156_M209C,beta-lactamase_156_209,TEM-1,beta-lactamase_156,P62593,1.01012,NO,209,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.442,-4.758,3.316,,,H,A,0.55,-0.97,1.066,,64.69,HHA,-1.52633,0.111618,0.00625021,1.01012 beta-lactamase_2500_T27V,beta-lactamase_2500_27,TEM-1,beta-lactamase_2500,P62593,1.01012,NO,27,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.905,-3.409,1.504,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.361275,0.00306559,1.01012 beta-lactamase_H285N,beta-lactamase_285,TEM-1,beta-lactamase,P62593,1.01012,NO,285,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-1.845,-2.277,0.432,5.64289,0.312,T,a,0.35,0.64,1.401,,72.73,BBH,-1.64567,0.221079,0.101555,1.01012 beta-lactamase_156_S283C,beta-lactamase_156_283,TEM-1,beta-lactamase_156,P62593,1.01013,NO,283,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.111618,0.0429138,1.01013 gb1_K276V,gb1_276,gb1,gb1,P06654,1.01013,NO,276,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.456,-3.459,2.003,,,,,,,0.236,,12.72,PBP,-1.65133,0.177985,0.00620493,1.01013 beta-lactamase_39_P172T,beta-lactamase_39_172,TEM-1,beta-lactamase_39,P62593,1.01014,NO,172,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.998,-3.409,2.411,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.0495842,0.00312594,1.01014 WW_domain_L190L,WW_domain_190,Yap65,WW_domain,P46937,1.01014,NO,190,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.404,-1.404,0,5.53598,,,,,,0.645,,56.55,HHP,-1.51833,0.153962,0.00249186,1.01014 beta-lactamase_156_E166D,beta-lactamase_156_166,TEM-1,beta-lactamase_156,P62593,1.01015,NO,166,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.756,-2.259,0.503,,0.508,G,A,1.04,1.05,2.393,,73.08,OAH,-1.42233,0.111618,0.00512989,1.01015 beta-lactamase_156_F149T,beta-lactamase_156_149,TEM-1,beta-lactamase_156,P62593,1.01015,NO,149,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.299,-3.669,2.37,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.111618,0.00418462,1.01015 beta-lactamase_156_T112L,beta-lactamase_156_112,TEM-1,beta-lactamase_156,P62593,1.01015,NO,112,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.186,-3.575,1.389,,0.921,T,A,0.22,1.06,2.87,,73.78,HPA,-1.925,0.111618,0.00531334,1.01015 beta-lactamase_0_G90I,beta-lactamase_0_90,TEM-1,beta-lactamase_0,P62593,1.01016,NO,90,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-2.091,-4.052,1.961,,0.598,T,A,0.29,0.32,2.04,,77.62,HOB,-1.52633,0.0500837,0.00490273,1.01016 beta-lactamase_39_E46Y,beta-lactamase_39_46,TEM-1,beta-lactamase_39,P62593,1.01016,NO,46,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.94,-4.198,2.258,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.0495842,0.00427568,1.01016 beta-lactamase_2500_T198S,beta-lactamase_2500_198,TEM-1,beta-lactamase_2500,P62593,1.01017,NO,198,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.168,-1.471,-0.697,,0.489,,B,0.22,-0.13,0.37,,73.78,HPH,-1.98767,0.361275,0.004311,1.01017 beta-lactamase_L10T,beta-lactamase_10,TEM-1,beta-lactamase,P62593,1.01017,NO,10,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.623,-2.524,0.901,,,,,,,2.467,,65.38,HHH,-1.83833,0.221079,0.00296968,1.01017 beta-lactamase_625_T139M,beta-lactamase_625_139,TEM-1,beta-lactamase_625,P62593,1.01018,NO,139,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.901,-4.659,2.758,,0.216,H,A,0.22,0.39,2.256,,77.62,PPH,-2.04667,0.213352,0.00441837,1.01018 beta-lactamase_156_E145R,beta-lactamase_156_145,TEM-1,beta-lactamase_156,P62593,1.0102,NO,145,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.357,-2.676,0.319,,0.545,H,A,1.04,0.79,3.661,,77.62,BAH,-2.069,0.111618,0.00553285,1.0102 Pab1_E161R,Pab1_161,Pab1,Pab1,P04147,1.0102,NO,161,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.474,-3.568,2.094,,0.663,T,a,,1.34,,,,AAP,-1.59067,0.175299,0.00276141,1.0102 beta-lactamase_Q203K,beta-lactamase_203,TEM-1,beta-lactamase,P62593,1.01021,NO,203,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.168,-2.642,0.474,5.65296,0.47,H,A,0.12,-0.38,1.66,,65.38,BPP,-1.614,0.221079,0.00631514,1.01021 PSD95pdz3_N326R,PSD95pdz3_326,PSD95pdz3,PSD95pdz3,P31016,1.01021,NO,326,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-1.41,-3.165,1.755,5.52537,,,,,19.0688,,,,HPH,-1.52133,0.0758425,0.00101078,1.01021 beta-lactamase_156_D271G,beta-lactamase_156_271,TEM-1,beta-lactamase_156,P62593,1.01022,NO,271,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.111618,0.00752082,1.01022 beta-lactamase_156_F58C,beta-lactamase_156_58,TEM-1,beta-lactamase_156,P62593,1.01022,NO,58,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-2.914,-5.093,2.179,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.111618,0.00523369,1.01022 beta-lactamase_39_P250A,beta-lactamase_39_250,TEM-1,beta-lactamase_39,P62593,1.01022,NO,250,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.0495842,0.00550899,1.01022 kka2_1:8_A176S,kka2_1:8_176,Kka2,kka2_1:8,P00552,1.01022,NO,176,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.621,-1.88,0.259,,0.806,H,A,0.46,-0.03,18.904,18.904,65.53,BHB,-2.26667,0.100394,0.0083587,1.01022 kka2_1:8_A176S,kka2_1:8_176,Kka2,kka2_1:8,P00552,1.01022,NO,176,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.621,-1.88,0.259,,0.806,H,A,0.46,-0.03,18.904,18.904,65.53,BHB,-2.26667,0.100394,0.0083587,1.01022 beta-lactamase_156_A170G,beta-lactamase_156_170,TEM-1,beta-lactamase_156,P62593,1.01023,NO,170,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.237,-1.884,0.647,,0.126,,L,0.46,-0.35,3.7,,64.69,AHH,-1.63267,0.111618,0.00431903,1.01023 beta-lactamase_39_A215K,beta-lactamase_39_215,TEM-1,beta-lactamase_39,P62593,1.01023,NO,215,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.503,-3.575,2.072,,,,a,0.46,-0.93,0.494,,74.48,HHO,-1.42633,0.0495842,0.00544007,1.01023 beta-lactamase_625_H151T,beta-lactamase_625_151,TEM-1,beta-lactamase_625,P62593,1.01023,NO,151,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-2.96,-3.492,0.532,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.213352,0.00216946,1.01023 beta-lactamase_39_R202D,beta-lactamase_39_202,TEM-1,beta-lactamase_39,P62593,1.01024,NO,202,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.292,-3.594,2.302,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.0495842,0.00321899,1.01024 beta-lactamase_39_K30R,beta-lactamase_39_30,TEM-1,beta-lactamase_39,P62593,1.01025,NO,30,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-2.307,-2.265,-0.042,,0.142,H,A,2.34,-0.65,6.717,,93.01,HBH,-2.32833,0.0495842,0.00448593,1.01025 beta-lactamase_39_L74M,beta-lactamase_39_74,TEM-1,beta-lactamase_39,P62593,1.01025,NO,74,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.296,-2.987,1.691,,,H,A,0.55,-0.91,1.581,,50,HHO,-1.34933,0.0495842,0.00493255,1.01025 beta-lactamase_39_S122D,beta-lactamase_39_122,TEM-1,beta-lactamase_39,P62593,1.01025,NO,122,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.406,-2.549,0.143,,0.352,H,A,0.27,-0.54,2.004,,77.62,OPH,-1.39767,0.0495842,0.00497825,1.01025 beta-lactamase_H94V,beta-lactamase_94,TEM-1,beta-lactamase,P62593,1.01025,NO,94,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-2.5,-2.751,0.251,6.1507,0.776,,B,0.63,1.24,1.176,,77.62,HBH,-1.872,0.221079,0.00389226,1.01025 beta-lactamase_156_I54V,beta-lactamase_156_54,TEM-1,beta-lactamase_156,P62593,1.01026,NO,54,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-2.838,-2.687,-0.151,,0.669,E,B,0.48,-0.14,0.541,,73.78,BHH,-2.337,0.111618,0.00403589,1.01026 beta-lactamase_39_A185M,beta-lactamase_39_185,TEM-1,beta-lactamase_39,P62593,1.01026,NO,185,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.406,-4.39,2.984,,,H,A,0.46,-1.02,2.68,,65.03,HHP,-1.84033,0.0495842,0.00467449,1.01026 beta-lactamase_2500_S80H,beta-lactamase_2500_80,TEM-1,beta-lactamase_2500,P62593,1.01027,NO,80,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.029,-3.359,1.33,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.361275,0.00565569,1.01027 beta-lactamase_625_Q86D,beta-lactamase_625_86,TEM-1,beta-lactamase_625,P62593,1.01028,NO,86,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.4,-2.27,-0.13,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.213352,0.00450027,1.01028 beta-lactamase_D207G,beta-lactamase_207,TEM-1,beta-lactamase,P62593,1.01028,NO,207,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.064,-2.283,0.219,5.40404,0.409,H,A,0.23,0.12,1.975,,77.62,HAH,-1.77033,0.221079,0.00592942,1.01028 gb1_T279V,gb1_279,gb1,gb1,P06654,1.01028,NO,279,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.32,-2.675,1.355,,,,,,,0.529,,35.71,HPH,-1.50067,0.177985,0.00421454,1.01028 beta-lactamase_625_L38Q,beta-lactamase_625_38,TEM-1,beta-lactamase_625,P62593,1.01029,NO,38,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.343,-4.155,2.812,,0.088,H,A,0.55,0.2,1.986,,64.34,PHO,-1.78033,0.213352,0.00373244,1.01029 beta-lactamase_156_L218M,beta-lactamase_156_218,TEM-1,beta-lactamase_156,P62593,1.0103,NO,218,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.391,-4.267,2.876,,,I,b,0.55,-0.53,17.202,17.202,74.48,OHH,-1.58867,0.111618,0.00618274,1.0103 beta-lactamase_156_R189N,beta-lactamase_156_189,TEM-1,beta-lactamase_156,P62593,1.0103,NO,189,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.844,-3.633,1.789,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.111618,0.0050699,1.0103 beta-lactamase_A225D,beta-lactamase_225,TEM-1,beta-lactamase,P62593,1.01031,NO,225,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.845,-2.561,0.716,6.5181,1,T,B,0.58,-0.38,4.077,,74.48,OHO,-1.39967,0.221079,0.00465057,1.01031 beta-lactamase_39_D155S,beta-lactamase_39_155,TEM-1,beta-lactamase_39,P62593,1.01032,NO,155,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.889,-3.185,2.296,,0.049,,B,0.75,-0.9,3.208,,64.69,OAB,-1.62267,0.0495842,0.00135315,1.01032 beta-lactamase_39_R275Q,beta-lactamase_39_275,TEM-1,beta-lactamase_39,P62593,1.01032,NO,275,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.0495842,0.0141984,1.01032 beta-lactamase_156_L188M,beta-lactamase_156_188,TEM-1,beta-lactamase_156,P62593,1.01033,NO,188,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.166,-2.706,1.54,,,H,A,0.55,-0.3,1.574,,60.14,PHB,-1.47033,0.111618,0.00295687,1.01033 beta-lactamase_156_A183R,beta-lactamase_156_183,TEM-1,beta-lactamase_156,P62593,1.01034,NO,183,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.231,-3.825,2.594,,0.155,H,A,0.46,-0.91,23.859,23.859,77.62,HHH,-1.53367,0.111618,0.00296631,1.01034 beta-lactamase_2500_R239N,beta-lactamase_2500_239,TEM-1,beta-lactamase_2500,P62593,1.01034,NO,239,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.361275,0.00213852,1.01034 beta-lactamase_39_K190A,beta-lactamase_39_190,TEM-1,beta-lactamase_39,P62593,1.01034,NO,190,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.994,-2.146,0.152,,0.371,H,A,2.34,0.16,1.513,,77.62,BBH,-1.64167,0.0495842,0.00574527,1.01034 beta-lactamase_625_A170P,beta-lactamase_625_170,TEM-1,beta-lactamase_625,P62593,1.01034,NO,170,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.237,-3.899,2.662,,0.126,,L,0.46,-0.35,3.626,,64.69,AHH,-1.63267,0.213352,0.00431903,1.01034 beta-lactamase_625_N152T,beta-lactamase_625_152,TEM-1,beta-lactamase_625,P62593,1.01034,NO,152,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-2.757,-2.377,-0.38,,0.863,H,A,0.61,0.92,2.061,,77.62,BPH,-2.97,0.213352,0.00471429,1.01034 beta-lactamase_E175H,beta-lactamase_175,TEM-1,beta-lactamase,P62593,1.01034,NO,175,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.336,-3.355,1.019,6.0311,0.551,,A,0.75,1.05,5.316,,77.62,AAB,-1.31233,0.221079,0.00482205,1.01034 beta-lactamase_39_I45M,beta-lactamase_39_45,TEM-1,beta-lactamase_39,P62593,1.01035,NO,45,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-2.421,-3.375,0.954,,,E,B,0.48,-0.3,2.256,,77.62,HHA,-2.30267,0.0495842,0.00452842,1.01035 beta-lactamase_625_A183C,beta-lactamase_625_183,TEM-1,beta-lactamase_625,P62593,1.01035,NO,183,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.231,-4.684,3.453,,0.155,H,A,0.46,-0.91,23.859,23.859,77.62,HHH,-1.53367,0.213352,0.00296631,1.01035 beta-lactamase_625_W163M,beta-lactamase_625_163,TEM-1,beta-lactamase_625,P62593,1.01035,NO,163,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-1.843,-3.104,1.261,,0.467,,B,0.47,-0.5,5.019,,63.99,BHA,-1.269,0.213352,0.00418955,1.01035 beta-lactamase_156_N274A,beta-lactamase_156_274,TEM-1,beta-lactamase_156,P62593,1.01036,NO,274,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.111618,0.0110418,1.01036 beta-lactamase_2500_L111V,beta-lactamase_2500_111,TEM-1,beta-lactamase_2500,P62593,1.01036,NO,111,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.76,-1.731,-0.029,,0.328,T,A,0.55,0.93,1.966,,64.34,BHP,-1.884,0.361275,0.00480671,1.01036 beta-lactamase_39_V117Y,beta-lactamase_39_117,TEM-1,beta-lactamase_39,P62593,1.01036,NO,117,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.53,-2.958,1.428,,,H,A,0.44,-0.34,1.182,,65.03,PHB,-1.741,0.0495842,0.00467906,1.01036 beta-lactamase_625_E145Q,beta-lactamase_625_145,TEM-1,beta-lactamase_625,P62593,1.01036,NO,145,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.357,-2.979,0.622,,0.545,H,A,1.04,0.79,2.64,,77.62,BAH,-2.069,0.213352,0.00553285,1.01036 beta-lactamase_156_S80N,beta-lactamase_156_80,TEM-1,beta-lactamase_156,P62593,1.01037,NO,80,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.029,-2.999,0.97,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.111618,0.00565569,1.01037 beta-lactamase_2500_A268E,beta-lactamase_2500_268,TEM-1,beta-lactamase_2500,P62593,1.01037,NO,268,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.361275,0.0102525,1.01037 beta-lactamase_39_V29F,beta-lactamase_39_29,TEM-1,beta-lactamase_39,P62593,1.01037,NO,29,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-2.856,-4.364,1.508,,0.733,H,A,0.44,-0.78,1.287,,93.01,HHB,-2.24733,0.0495842,0.00318969,1.01037 beta-lactamase_156_L49A,beta-lactamase_156_49,TEM-1,beta-lactamase_156,P62593,1.01038,NO,49,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.897,-3.125,1.228,,0.131,T,A,0.55,0.04,3.112,,64.69,AHP,-1.99233,0.111618,0.00401477,1.01038 beta-lactamase_2500_V29C,beta-lactamase_2500_29,TEM-1,beta-lactamase_2500,P62593,1.01038,NO,29,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-2.856,-5.117,2.261,,0.733,H,A,0.44,-0.78,1.931,,93.01,HHB,-2.24733,0.361275,0.00318969,1.01038 kka2_1:8_I246Y,kka2_1:8_246,Kka2,kka2_1:8,P00552,1.01038,NO,246,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-2.008,-4.266,2.258,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.100394,0.0139479,1.01038 kka2_1:8_I246Y,kka2_1:8_246,Kka2,kka2_1:8,P00552,1.01038,NO,246,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-2.008,-4.266,2.258,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.100394,0.0139479,1.01038 PSD95pdz3_I316G,PSD95pdz3_316,PSD95pdz3,PSD95pdz3,P31016,1.01038,NO,316,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.63,-3.49,1.86,5.46166,,,,,19.005,,,,HHB,-1.62733,0.0758425,0.00112762,1.01038 beta-lactamase_625_E195P,beta-lactamase_625_195,TEM-1,beta-lactamase_625,P62593,1.01039,NO,195,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.186,-2.83,0.644,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.213352,0.00496565,1.01039 beta-lactamase_625_R189F,beta-lactamase_625_189,TEM-1,beta-lactamase_625,P62593,1.01039,NO,189,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.844,-4.275,2.431,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.213352,0.0050699,1.01039 beta-lactamase_625_R202S,beta-lactamase_625_202,TEM-1,beta-lactamase_625,P62593,1.01039,NO,202,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.292,-2.609,1.317,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.213352,0.00321899,1.01039 beta-lactamase_T267D,beta-lactamase_267,TEM-1,beta-lactamase,P62593,1.01039,NO,267,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.308,-2.141,-0.167,5.28263,0.54,,B,0.69,-0.14,0.374,,73.78,HPH,-1.9,0.221079,0.0102128,1.01039 beta-lactamase_156_G194W,beta-lactamase_156_194,TEM-1,beta-lactamase_156,P62593,1.0104,NO,194,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.396,-5.42,4.024,,0.276,S,b,0.29,0.36,1.346,,67.83,POA,-1.832,0.111618,0.00392163,1.0104 beta-lactamase_39_H156F,beta-lactamase_39_156,TEM-1,beta-lactamase_39,P62593,1.0104,NO,156,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-3.156,-4.428,1.272,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.0495842,0.00468596,1.0104 beta-lactamase_156_E61I,beta-lactamase_156_61,TEM-1,beta-lactamase_156,P62593,1.01041,NO,61,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.115,-4.14,2.025,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.111618,0.00440955,1.01041 beta-lactamase_156_S51N,beta-lactamase_156_51,TEM-1,beta-lactamase_156,P62593,1.01041,NO,51,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.526,-2.556,1.03,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.111618,0.00504821,1.01041 beta-lactamase_625_H24M,beta-lactamase_625_24,TEM-1,beta-lactamase_625,P62593,1.01041,NO,24,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-2.481,-3.144,0.663,,,,,,,2.708,,93.01,OBO,-2.0035,0.213352,0.00238894,1.01041 beta-lactamase_0_G234P,beta-lactamase_0_234,TEM-1,beta-lactamase_0,P62593,1.01043,NO,234,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.62,-3.88,3.26,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.0500837,0.000889577,1.01043 Pab1_P135T,Pab1_135,Pab1,Pab1,P04147,1.01043,NO,135,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.457,-3.252,1.795,,,,,,,6.41,,81.8,BOA,-1.53367,0.175299,0.00148028,1.01043 beta-lactamase_156_R81F,beta-lactamase_156_81,TEM-1,beta-lactamase_156,P62593,1.01044,NO,81,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.466,-4.359,2.893,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.111618,0.00499763,1.01044 beta-lactamase_39_E46T,beta-lactamase_39_46,TEM-1,beta-lactamase_39,P62593,1.01044,NO,46,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.94,-3.517,1.577,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.0495842,0.00427568,1.01044 beta-lactamase_625_G234S,beta-lactamase_625_234,TEM-1,beta-lactamase_625,P62593,1.01044,NO,234,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.62,-3.161,2.541,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.213352,0.000889577,1.01044 beta-lactamase_39_P255Q,beta-lactamase_39_255,TEM-1,beta-lactamase_39,P62593,1.01045,NO,255,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.0495842,0.00499612,1.01045 beta-lactamase_A185G,beta-lactamase_185,TEM-1,beta-lactamase,P62593,1.01045,NO,185,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.406,-3.37,1.964,4.89877,,H,A,2.34,-1.02,2.999,,65.03,HHP,-1.84033,0.221079,0.00467449,1.01045 beta-lactamase_39_L150W,beta-lactamase_39_150,TEM-1,beta-lactamase_39,P62593,1.01047,NO,150,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.326,-5.247,3.921,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.0495842,0.00463171,1.01047 beta-lactamase_39_Q267T,beta-lactamase_39_267,TEM-1,beta-lactamase_39,P62593,1.01047,NO,267,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.308,-3.09,0.782,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.0495842,0.0102128,1.01047 beta-lactamase_39_T112D,beta-lactamase_39_112,TEM-1,beta-lactamase_39,P62593,1.01047,NO,112,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.186,-2.66,0.474,,0.921,T,A,0.22,1.06,2.87,,73.78,HPA,-1.925,0.0495842,0.00531334,1.01047 beta-lactamase_625_R275Q,beta-lactamase_625_275,TEM-1,beta-lactamase_625,P62593,1.01047,NO,275,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.213352,0.0141984,1.01047 kka2_1:4_R253N,kka2_1:4_253,Kka2,kka2_1:4,P00552,1.01047,NO,253,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.356,-3.661,2.305,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.168804,0.0144195,1.01047 beta-lactamase_156_Q88E,beta-lactamase_156_88,TEM-1,beta-lactamase_156,P62593,1.01048,NO,88,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.086,-2.76,0.674,,0.807,,B,0.64,2.03,0.911,,77.62,APH,-1.53433,0.111618,0.00504167,1.01048 beta-lactamase_39_R242M,beta-lactamase_39_242,TEM-1,beta-lactamase_39,P62593,1.01048,NO,242,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.0495842,0.00452879,1.01048 beta-lactamase_39_S96M,beta-lactamase_39_96,TEM-1,beta-lactamase_39,P62593,1.01048,NO,96,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.27,-3.49,1.22,,0.368,,b,0.27,0.39,2.516,,73.78,HPP,-2.019,0.0495842,0.00551835,1.01048 beta-lactamase_39_T126P,beta-lactamase_39_126,TEM-1,beta-lactamase_39,P62593,1.01048,NO,126,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.122,-3.758,2.636,,0.05,H,A,0.22,-0.05,0.586,,44.41,HPH,-1.60467,0.0495842,0.00244552,1.01048 beta-lactamase_2500_D36G,beta-lactamase_2500_36,TEM-1,beta-lactamase_2500,P62593,1.01049,NO,36,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.732,-2.829,0.097,,0.555,H,A,0.75,1.17,2.26,,77.62,AAP,-1.91167,0.361275,0.00476483,1.01049 beta-lactamase_39_G85L,beta-lactamase_39_85,TEM-1,beta-lactamase_39,P62593,1.01049,NO,85,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.011,-3.755,2.744,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.0495842,0.00252173,1.01049 beta-lactamase_156_S256D,beta-lactamase_156_256,TEM-1,beta-lactamase_156,P62593,1.0105,NO,256,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.111618,0.00710634,1.0105 beta-lactamase_156_V157C,beta-lactamase_156_157,TEM-1,beta-lactamase_156,P62593,1.0105,NO,157,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.751,-4.91,3.159,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.111618,0.00506849,1.0105 beta-lactamase_625_H156M,beta-lactamase_625_156,TEM-1,beta-lactamase_625,P62593,1.0105,NO,156,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-3.156,-3.543,0.387,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.213352,0.00468596,1.0105 PSD95pdz3_L353V,PSD95pdz3_353,PSD95pdz3,PSD95pdz3,P31016,1.0105,NO,353,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.347,-2.535,1.188,5.81136,,,,,17.3525,,,,AHB,-1.50533,0.0758425,0.000664742,1.0105 beta-lactamase_0_Q276M,beta-lactamase_0_276,TEM-1,beta-lactamase_0,P62593,1.01051,NO,276,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.0500837,0.0191712,1.01051 beta-lactamase_0_R92L,beta-lactamase_0_92,TEM-1,beta-lactamase_0,P62593,1.01051,NO,92,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.718,-2.788,1.07,,0.479,E,B,1.2,1.36,2.331,,65.38,BBH,-1.50367,0.0500837,0.00429626,1.01051 beta-lactamase_625_T112I,beta-lactamase_625_112,TEM-1,beta-lactamase_625,P62593,1.01051,NO,112,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.186,-3.949,1.763,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.213352,0.00531334,1.01051 beta-lactamase_E61Y,beta-lactamase_61,TEM-1,beta-lactamase,P62593,1.01051,NO,61,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.115,-4.403,2.288,6.29701,0.775,T,a,0.52,1.29,1.975,,77.62,OAA,-1.92567,0.221079,0.00440955,1.01051 beta-lactamase_I229I,beta-lactamase_229,TEM-1,beta-lactamase,P62593,1.01051,NO,229,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.267,-1.267,,5.0911,0.083,E,B,1,-0.76,1.114,,50,HHH,-1.58767,0.221079,0.00477249,1.01051 beta-lactamase_156_L150G,beta-lactamase_156_150,TEM-1,beta-lactamase_156,P62593,1.01052,NO,150,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.326,-3.622,2.296,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.111618,0.00463171,1.01052 beta-lactamase_39_E46Q,beta-lactamase_39_46,TEM-1,beta-lactamase_39,P62593,1.01052,NO,46,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.94,-4.007,2.067,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.0495842,0.00427568,1.01052 beta-lactamase_39_P65I,beta-lactamase_39_65,TEM-1,beta-lactamase_39,P62593,1.01052,NO,65,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.894,-3.716,2.822,,0.098,E,B,0.52,-0.62,0.623,,40.56,HOH,-1.03233,0.0495842,0.00152776,1.01052 beta-lactamase_625_P60T,beta-lactamase_625_60,TEM-1,beta-lactamase_625,P62593,1.01052,NO,60,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-2.469,-3.483,1.014,,0.256,T,A,0.52,-0.56,3.653,,77.62,BOA,-1.97633,0.213352,0.00521318,1.01052 beta-lactamase_625_S201L,beta-lactamase_625_201,TEM-1,beta-lactamase_625,P62593,1.01052,NO,201,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.183,-2.615,1.432,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.213352,0.00198815,1.01052 beta-lactamase_625_T186D,beta-lactamase_625_186,TEM-1,beta-lactamase_625,P62593,1.01052,NO,186,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.522,-2.935,0.413,,0.396,H,A,0.22,-0.28,0.515,,77.62,HPP,-1.77633,0.213352,0.00485034,1.01052 beta-lactamase_E175D,beta-lactamase_175,TEM-1,beta-lactamase,P62593,1.01052,NO,175,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.336,-2.916,0.58,6.0311,0.551,,A,0.75,1.05,5.316,,77.62,AAB,-1.31233,0.221079,0.00482205,1.01052 beta-lactamase_0_C75D,beta-lactamase_0_75,TEM-1,beta-lactamase_0,P62593,1.01053,NO,75,C,D,CD,Special,negativeCharge,5.07,5.0516,-0.0184,154,121,133,12,108.5,111.1,2.6,-1.245,-3.832,2.587,,,H,A,0.46,-0.87,2.256,,50,HOO,-1.24333,0.0500837,0.0034616,1.01053 beta-lactamase_0_P172W,beta-lactamase_0_172,TEM-1,beta-lactamase_0,P62593,1.01053,NO,172,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.998,-5.528,4.53,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.0500837,0.00312594,1.01053 beta-lactamase_39_L146F,beta-lactamase_39_146,TEM-1,beta-lactamase_39,P62593,1.01053,NO,146,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.462,-2.298,0.836,,0.007,H,A,0.55,-0.56,1.953,,64.69,AHP,-1.656,0.0495842,0.00474542,1.01053 beta-lactamase_625_L73S,beta-lactamase_625_73,TEM-1,beta-lactamase_625,P62593,1.01054,NO,73,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.507,-3.664,2.157,,,H,A,0.55,-0.64,2.933,,67.83,HHH,-1.487,0.213352,0.00488983,1.01054 beta-lactamase_156_K109Y,beta-lactamase_156_109,TEM-1,beta-lactamase_156,P62593,1.01055,NO,109,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.734,-4.334,2.6,,0.787,G,A,2.34,2.21,6.031,,72.73,ABB,-1.63333,0.111618,0.00462493,1.01055 beta-lactamase_39_A148H,beta-lactamase_39_148,TEM-1,beta-lactamase_39,P62593,1.01055,NO,148,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.757,-3.344,1.587,,0.379,H,A,0.46,-0.55,3.551,,72.73,PHH,-1.40167,0.0495842,0.00547053,1.01055 beta-lactamase_625_D36R,beta-lactamase_625_36,TEM-1,beta-lactamase_625,P62593,1.01055,NO,36,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.732,-2.847,0.115,,0.555,H,A,0.75,1.17,2.26,,77.62,AAP,-1.91167,0.213352,0.00476483,1.01055 beta-lactamase_K53K,beta-lactamase_53,TEM-1,beta-lactamase,P62593,1.01056,NO,53,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-2.313,-2.313,,5.93654,0.589,,B,1.82,1.15,19.72,19.72,77.62,OBH,-2.1,0.221079,0.00383383,1.01056 beta-lactamase_L150L,beta-lactamase_150,TEM-1,beta-lactamase,P62593,1.01056,NO,150,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.326,-1.326,,5.15566,,H,A,1.75,-0.2,1.615,,62.94,HHB,-1.86167,0.221079,0.00463171,1.01056 kka2_1:4_D5Y,kka2_1:4_5,Kka2,kka2_1:4,P00552,1.01056,NO,5,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.306,-4.118,2.812,,,,,,,,,71.59,PAO,-1.784,0.168804,0.00222864,1.01056 beta-lactamase_156_L38Y,beta-lactamase_156_38,TEM-1,beta-lactamase_156,P62593,1.01057,NO,38,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.343,-2.956,1.613,,0.088,H,A,0.55,0.2,13.556,13.556,64.34,PHO,-1.78033,0.111618,0.00373244,1.01057 beta-lactamase_156_L196R,beta-lactamase_156_196,TEM-1,beta-lactamase_156,P62593,1.01058,NO,196,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-2.478,-2.59,0.112,,0.518,S,A,0.55,1.35,7.897,,77.62,AHH,-1.839,0.111618,0.00512144,1.01058 beta-lactamase_156_R159T,beta-lactamase_156_159,TEM-1,beta-lactamase_156,P62593,1.01058,NO,159,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-0.94,-3.47,2.53,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.111618,0.00108472,1.01058 PSD95pdz3_L349T,PSD95pdz3_349,PSD95pdz3,PSD95pdz3,P31016,1.01058,NO,349,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.347,-3.103,1.756,5.14696,,,,,24.6438,,,,AHP,-1.37667,0.0758425,0.00071841,1.01058 beta-lactamase_39_K190T,beta-lactamase_39_190,TEM-1,beta-lactamase_39,P62593,1.01059,NO,190,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.994,-2.389,0.395,,0.371,H,A,2.34,0.16,1.513,,77.62,BBH,-1.64167,0.0495842,0.00574527,1.01059 beta-lactamase_39_R92G,beta-lactamase_39_92,TEM-1,beta-lactamase_39,P62593,1.01059,NO,92,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.718,-3.552,1.834,,0.479,E,B,1.2,1.36,0.389,,65.38,BBH,-1.50367,0.0495842,0.00429626,1.01059 gb1_T277G,gb1_277,gb1,gb1,P06654,1.01059,NO,277,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.771,-3.123,1.352,,,,,,,0.824,,35.71,BPH,-1.54833,0.177985,0.00348258,1.01059 kka2_1:4_L103M,kka2_1:4_103,Kka2,kka2_1:4,P00552,1.0106,NO,103,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-2.362,-4.518,2.156,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.168804,0.00574792,1.0106 beta-lactamase_39_R118T,beta-lactamase_39_118,TEM-1,beta-lactamase_39,P62593,1.01061,NO,118,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.413,-2.845,0.432,,0.457,H,A,1.2,1.39,3.961,,77.62,HBA,-1.785,0.0495842,0.00538794,1.01061 beta-lactamase_156_I244Y,beta-lactamase_156_244,TEM-1,beta-lactamase_156,P62593,1.01062,NO,244,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.555,-4.031,2.476,,,E,B,0.48,-0.84,1.325,,77.62,OHH,-1.385,0.111618,0.00605379,1.01062 beta-lactamase_39_V82K,beta-lactamase_39_82,TEM-1,beta-lactamase_39,P62593,1.01063,NO,82,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.325,-3.754,2.429,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.0495842,0.00397046,1.01063 beta-lactamase_625_I244M,beta-lactamase_625_244,TEM-1,beta-lactamase_625,P62593,1.01063,NO,244,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.555,-4.138,2.583,,,E,B,0.48,-0.84,2.061,,77.62,OHH,-1.385,0.213352,0.00605379,1.01063 beta-lactamase_625_K30T,beta-lactamase_625_30,TEM-1,beta-lactamase_625,P62593,1.01063,NO,30,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-2.307,-2.199,-0.108,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.213352,0.00448593,1.01063 beta-lactamase_A215A,beta-lactamase_215,TEM-1,beta-lactamase,P62593,1.01064,NO,215,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.503,-1.503,,4.82164,,,a,0.75,-0.93,3.583,,74.48,HHO,-1.42633,0.221079,0.00544007,1.01064 beta-lactamase_D113E,beta-lactamase_113,TEM-1,beta-lactamase,P62593,1.01064,NO,113,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.829,-2.32,0.491,6.04499,0.665,T,A,0.23,0.91,21.104,21.104,73.08,PAO,-1.703,0.221079,0.00474112,1.01064 beta-lactamase_D33I,beta-lactamase_33,TEM-1,beta-lactamase,P62593,1.01064,NO,33,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.321,-3.065,0.744,5.05203,0.366,H,A,0.23,0.33,2.032,,77.62,BAH,-2.12133,0.221079,0.00435556,1.01064 beta-lactamase_39_T198S,beta-lactamase_39_198,TEM-1,beta-lactamase_39,P62593,1.01065,NO,198,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.168,-1.471,-0.697,,0.489,,B,0.22,-0.13,3.614,,73.78,HPH,-1.98767,0.0495842,0.004311,1.01065 kka2_1:4_I29D,kka2_1:4_29,Kka2,kka2_1:4,P00552,1.01065,NO,29,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.692,-3.047,1.355,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.168804,0.00619521,1.01065 beta-lactamase_156_R162H,beta-lactamase_156_162,TEM-1,beta-lactamase_156,P62593,1.01066,NO,162,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.016,-4.37,3.354,,0.124,S,B,1.2,-0.37,7.444,,64.69,ABH,-1.25,0.111618,0.000561334,1.01066 beta-lactamase_39_E272I,beta-lactamase_39_272,TEM-1,beta-lactamase_39,P62593,1.01066,NO,272,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.127,,,,0.081,H,A,0.43,-0.97,12.983,12.983,63.64,AAB,-1.56333,0.0495842,0.00545371,1.01066 beta-lactamase_156_R162M,beta-lactamase_156_162,TEM-1,beta-lactamase_156,P62593,1.01068,NO,162,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.016,-4.454,3.438,,0.124,S,B,1.2,-0.37,7.444,,64.69,ABH,-1.25,0.111618,0.000561334,1.01068 beta-lactamase_156_S256T,beta-lactamase_156_256,TEM-1,beta-lactamase_156,P62593,1.01068,NO,256,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.111618,0.00710634,1.01068 beta-lactamase_2500_E61F,beta-lactamase_2500_61,TEM-1,beta-lactamase_2500,P62593,1.01068,NO,61,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.115,-4.422,2.307,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.361275,0.00440955,1.01068 beta-lactamase_39_H151Y,beta-lactamase_39_151,TEM-1,beta-lactamase_39,P62593,1.01068,NO,151,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-2.96,-4.115,1.155,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.0495842,0.00216946,1.01068 beta-lactamase_156_E279S,beta-lactamase_156_279,TEM-1,beta-lactamase_156,P62593,1.01069,NO,279,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.111618,0.0192826,1.01069 beta-lactamase_2500_Q267Y,beta-lactamase_2500_267,TEM-1,beta-lactamase_2500,P62593,1.01069,NO,267,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.361275,0.0102128,1.01069 beta-lactamase_625_N274G,beta-lactamase_625_274,TEM-1,beta-lactamase_625,P62593,1.01069,NO,274,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.213352,0.0110418,1.01069 beta-lactamase_2500_H24S,beta-lactamase_2500_24,TEM-1,beta-lactamase_2500,P62593,1.0107,NO,24,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-2.481,-1.903,-0.578,,,,,,,0.467,,93.01,OBO,-2.0035,0.361275,0.00238894,1.0107 beta-lactamase_39_M67H,beta-lactamase_39_67,TEM-1,beta-lactamase_39,P62593,1.0107,NO,67,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-2.231,-4.763,2.532,,0.006,G,P,0.55,-0.81,1.463,,65.03,HHP,-1.502,0.0495842,0.00409753,1.0107 kka2_1:4_R143Y,kka2_1:4_143,Kka2,kka2_1:4,P00552,1.0107,NO,143,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.525,-4.353,1.828,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.168804,0.00662247,1.0107 PSD95pdz3_A343M,PSD95pdz3_343,PSD95pdz3,PSD95pdz3,P31016,1.0107,NO,343,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.307,-4.162,2.855,5.585,,,,,14.728,,,,HHO,-1.22067,0.0758425,0.000798084,1.0107 beta-lactamase_0_A230F,beta-lactamase_0_230,TEM-1,beta-lactamase_0,P62593,1.01071,NO,230,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.154,-4.217,3.063,,0.01,E,B,0.46,-1.17,2.179,,50,HHA,-1.079,0.0500837,0.00516841,1.01071 beta-lactamase_156_W163I,beta-lactamase_156_163,TEM-1,beta-lactamase_156,P62593,1.01071,NO,163,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-1.843,-3.136,1.293,,0.467,,B,0.47,-0.5,15.095,15.095,63.99,BHA,-1.269,0.111618,0.00418955,1.01071 beta-lactamase_2500_V29K,beta-lactamase_2500_29,TEM-1,beta-lactamase_2500,P62593,1.01071,NO,29,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-2.856,-2.195,-0.661,,0.733,H,A,0.44,-0.78,1.931,,93.01,HHB,-2.24733,0.361275,0.00318969,1.01071 kka2_1:2_R121D,kka2_1:2_121,Kka2,kka2_1:2,P00552,1.01071,NO,121,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.552,-3.714,2.162,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.295029,0.00523326,1.01071 beta-lactamase_156_K32Y,beta-lactamase_156_32,TEM-1,beta-lactamase_156,P62593,1.01072,NO,32,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.984,-4.317,2.333,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.111618,0.00401283,1.01072 beta-lactamase_156_L150I,beta-lactamase_156_150,TEM-1,beta-lactamase_156,P62593,1.01072,NO,150,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.326,-3.18,1.854,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.111618,0.00463171,1.01072 beta-lactamase_625_P25W,beta-lactamase_625_25,TEM-1,beta-lactamase_625,P62593,1.01072,NO,25,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.526,-5.419,3.893,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.213352,0.00347571,1.01072 beta-lactamase_D269A,beta-lactamase_269,TEM-1,beta-lactamase,P62593,1.01072,NO,269,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.156,-1.756,-0.4,5.47645,0.646,H,A,0.23,0.4,21.796,21.796,77.62,HAA,-1.96733,0.221079,0.00950944,1.01072 beta-lactamase_156_E279R,beta-lactamase_156_279,TEM-1,beta-lactamase_156,P62593,1.01073,NO,279,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.111618,0.0192826,1.01073 beta-lactamase_156_F70Y,beta-lactamase_156_70,TEM-1,beta-lactamase_156,P62593,1.01073,NO,70,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.169,-2.563,1.394,,,H,A,0.58,-1.34,1.918,,63.99,PHB,-0.980667,0.111618,0.00193499,1.01073 beta-lactamase_156_A225D,beta-lactamase_156_225,TEM-1,beta-lactamase_156,P62593,1.01075,NO,225,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.845,-2.561,0.716,,1,T,B,0.46,-0.38,11.722,11.722,74.48,OHO,-1.39967,0.111618,0.00465057,1.01075 beta-lactamase_39_S104M,beta-lactamase_39_104,TEM-1,beta-lactamase_39,P62593,1.01075,NO,104,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.015,-4.54,3.525,,0.04,,b,0.27,0.57,4.02,,63.29,HPO,-1.05267,0.0495842,0.00218083,1.01075 beta-lactamase_625_P60D,beta-lactamase_625_60,TEM-1,beta-lactamase_625,P62593,1.01075,NO,60,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-2.469,-3.676,1.207,,0.256,T,A,0.52,-0.56,3.653,,77.62,BOA,-1.97633,0.213352,0.00521318,1.01075 beta-lactamase_156_Q37I,beta-lactamase_156_37,TEM-1,beta-lactamase_156,P62593,1.01076,NO,37,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.134,-4.024,1.89,,0.613,H,A,0.64,1.98,12.052,12.052,73.08,APH,-2.06967,0.111618,0.00425833,1.01076 beta-lactamase_39_M270G,beta-lactamase_39_270,TEM-1,beta-lactamase_39,P62593,1.01076,NO,270,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.0495842,0.00767762,1.01076 beta-lactamase_P60E,beta-lactamase_60,TEM-1,beta-lactamase,P62593,1.01076,NO,60,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-2.469,-2.856,0.387,5.51353,0.256,T,A,0.73,-0.56,3.653,,77.62,BOA,-1.97633,0.221079,0.00521318,1.01076 Pab1_G167N,Pab1_167,Pab1,Pab1,P04147,1.01076,NO,167,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.223,-3.52,2.297,,0.195,S,g,,0.03,,,,BOH,-1.25133,0.175299,0.00146449,1.01076 beta-lactamase_39_E279R,beta-lactamase_39_279,TEM-1,beta-lactamase_39,P62593,1.01077,NO,279,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.0495842,0.0192826,1.01077 beta-lactamase_625_E195G,beta-lactamase_625_195,TEM-1,beta-lactamase_625,P62593,1.01077,NO,195,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.186,-2.611,0.425,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.213352,0.00496565,1.01077 beta-lactamase_625_K109A,beta-lactamase_625_109,TEM-1,beta-lactamase_625,P62593,1.01077,NO,109,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.734,-3.283,1.549,,0.787,G,A,2.34,2.21,7.243,,72.73,ABB,-1.63333,0.213352,0.00462493,1.01077 kka2_1:4_D250P,kka2_1:4_250,Kka2,kka2_1:4,P00552,1.01077,NO,250,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.015,-3.798,2.783,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.168804,0.0177103,1.01077 PSD95pdz3_R312M,PSD95pdz3_312,PSD95pdz3,PSD95pdz3,P31016,1.01077,NO,312,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.582,-4.162,2.58,5.76826,,,,,12.2409,,,,OBB,-1.46667,0.0758425,0.00196255,1.01077 beta-lactamase_156_A282T,beta-lactamase_156_282,TEM-1,beta-lactamase_156,P62593,1.01078,NO,282,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.111618,0.0449821,1.01078 beta-lactamase_39_T147I,beta-lactamase_39_147,TEM-1,beta-lactamase_39,P62593,1.01078,NO,147,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.149,-2.792,1.643,,0.281,H,A,0.22,-0.68,13.843,13.843,64.34,HPH,-1.456,0.0495842,0.00226017,1.01078 beta-lactamase_625_D36W,beta-lactamase_625_36,TEM-1,beta-lactamase_625,P62593,1.01078,NO,36,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.732,-5.422,2.69,,0.555,H,A,0.75,1.17,2.26,,77.62,AAP,-1.91167,0.213352,0.00476483,1.01078 beta-lactamase_39_L196D,beta-lactamase_39_196,TEM-1,beta-lactamase_39,P62593,1.01079,NO,196,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-2.478,-3.862,1.384,,0.518,S,A,0.55,1.35,12.152,12.152,77.62,AHH,-1.839,0.0495842,0.00512144,1.01079 beta-lactamase_39_T198N,beta-lactamase_39_198,TEM-1,beta-lactamase_39,P62593,1.01079,NO,198,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.168,-3.569,1.401,,0.489,,B,0.22,-0.13,3.614,,73.78,HPH,-1.98767,0.0495842,0.004311,1.01079 beta-lactamase_39_V157T,beta-lactamase_39_157,TEM-1,beta-lactamase_39,P62593,1.01079,NO,157,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.751,-2.302,0.551,,0.308,S,a,0.44,-0.75,10.364,10.364,69.58,BHP,-2.00767,0.0495842,0.00506849,1.01079 beta-lactamase_625_N152H,beta-lactamase_625_152,TEM-1,beta-lactamase_625,P62593,1.01079,NO,152,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-2.757,-3.372,0.615,,0.863,H,A,0.61,0.92,2.061,,77.62,BPH,-2.97,0.213352,0.00471429,1.01079 kka2_1:8_E161G,kka2_1:8_161,Kka2,kka2_1:8,P00552,1.01079,NO,161,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.581,-3.389,1.808,,0.829,G,A,1.04,2.24,11.923,11.923,92.05,AAB,-1.861,0.100394,0.00760103,1.01079 kka2_1:8_E161G,kka2_1:8_161,Kka2,kka2_1:8,P00552,1.01079,NO,161,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.581,-3.389,1.808,,0.829,G,A,1.04,2.24,11.923,11.923,92.05,AAB,-1.861,0.100394,0.00760103,1.01079 beta-lactamase_2500_A40G,beta-lactamase_2500_40,TEM-1,beta-lactamase_2500,P62593,1.0108,NO,40,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.402,-1.32,-0.082,,0.155,S,B,0.46,0.21,0.953,,73.78,OHB,-1.40267,0.361275,0.00490026,1.0108 beta-lactamase_39_F228T,beta-lactamase_39_228,TEM-1,beta-lactamase_39,P62593,1.0108,NO,228,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-2.342,-2.522,0.18,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.0495842,0.0046669,1.0108 beta-lactamase_0_I285H,beta-lactamase_0_285,TEM-1,beta-lactamase_0,P62593,1.01081,NO,285,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.845,-3.788,1.943,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.0500837,0.101555,1.01081 beta-lactamase_39_L191V,beta-lactamase_39_191,TEM-1,beta-lactamase_39,P62593,1.01081,NO,191,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.087,-2.22,1.133,,,H,A,0.55,0.09,1.372,,63.29,BHH,-1.445,0.0495842,0.00263549,1.01081 beta-lactamase_625_M127W,beta-lactamase_625_127,TEM-1,beta-lactamase_625,P62593,1.01081,NO,127,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-2.251,-3.502,1.251,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.213352,0.00437927,1.01081 beta-lactamase_156_F149H,beta-lactamase_156_149,TEM-1,beta-lactamase_156,P62593,1.01082,NO,149,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.299,-4.304,3.005,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.111618,0.00418462,1.01082 beta-lactamase_39_P105R,beta-lactamase_39_105,TEM-1,beta-lactamase_39,P62593,1.01082,NO,105,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.813,-3.93,3.117,,0.226,T,A,0.52,0.8,1.222,,63.29,POH,-1.01533,0.0495842,0.0011981,1.01082 kka2_1:4_L60C,kka2_1:4_60,Kka2,kka2_1:4,P00552,1.01082,NO,60,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.997,-4.773,3.776,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.168804,0.00262176,1.01082 beta-lactamase_39_T112R,beta-lactamase_39_112,TEM-1,beta-lactamase_39,P62593,1.01083,NO,112,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.186,-3.88,1.694,,0.921,T,A,0.22,1.06,2.87,,73.78,HPA,-1.925,0.0495842,0.00531334,1.01083 WW_domain_E178Q,WW_domain_178,Yap65,WW_domain,P46937,1.01083,NO,178,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.158,-3.001,1.843,5.22323,,,,,,,,,HAH,-1.299,0.153962,0.0016738,1.01083 beta-lactamase_156_F149V,beta-lactamase_156_149,TEM-1,beta-lactamase_156,P62593,1.01084,NO,149,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.299,-3.45,2.151,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.111618,0.00418462,1.01084 beta-lactamase_625_N152I,beta-lactamase_625_152,TEM-1,beta-lactamase_625,P62593,1.01084,NO,152,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-2.757,-3.192,0.435,,0.863,H,A,0.61,0.92,2.061,,77.62,BPH,-2.97,0.213352,0.00471429,1.01084 beta-lactamase_T179T,beta-lactamase_179,TEM-1,beta-lactamase,P62593,1.01084,NO,179,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.085,-1.085,,5.07116,,E,B,0.8,-1.38,1.859,,73.08,PPH,-1.557,0.221079,0.00226045,1.01084 beta-lactamase_156_A182G,beta-lactamase_156_182,TEM-1,beta-lactamase_156,P62593,1.01085,NO,182,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.777,-3.408,1.631,,0.136,H,A,0.46,-0.66,16.784,16.784,93.01,OHH,-1.27367,0.111618,0.00559099,1.01085 beta-lactamase_156_K109S,beta-lactamase_156_109,TEM-1,beta-lactamase_156,P62593,1.01086,NO,109,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.734,-2.861,1.127,,0.787,G,A,2.34,2.21,6.031,,72.73,ABB,-1.63333,0.111618,0.00462493,1.01086 PSD95pdz3_L349V,PSD95pdz3_349,PSD95pdz3,PSD95pdz3,P31016,1.01086,NO,349,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.347,-2.535,1.188,5.14696,,,,,24.6438,,,,AHP,-1.37667,0.0758425,0.00071841,1.01086 beta-lactamase_156_S221D,beta-lactamase_156_221,TEM-1,beta-lactamase_156,P62593,1.01087,NO,221,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.754,-3.645,1.891,,0.624,H,A,0.27,-0.2,17.729,17.729,74.48,BPH,-1.59967,0.111618,0.0046094,1.01087 beta-lactamase_625_A183Y,beta-lactamase_625_183,TEM-1,beta-lactamase_625,P62593,1.01087,NO,183,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.231,-4.261,3.03,,0.155,H,A,0.46,-0.91,23.859,23.859,77.62,HHH,-1.53367,0.213352,0.00296631,1.01087 beta-lactamase_625_A268E,beta-lactamase_625_268,TEM-1,beta-lactamase_625,P62593,1.01087,NO,268,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.213352,0.0102525,1.01087 beta-lactamase_625_C75V,beta-lactamase_625_75,TEM-1,beta-lactamase_625,P62593,1.01087,NO,75,C,V,CV,Special,Hydrophobic,5.07,5.60847,0.538465,192,121,117,-4,108.5,140,31.5,-1.245,-3.383,2.138,,,H,A,0.46,-0.87,2.141,,50,HOO,-1.24333,0.213352,0.0034616,1.01087 beta-lactamase_625_Q86V,beta-lactamase_625_86,TEM-1,beta-lactamase_625,P62593,1.01087,NO,86,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.4,-2.988,0.588,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.213352,0.00450027,1.01087 PSD95pdz3_L360T,PSD95pdz3_360,PSD95pdz3,PSD95pdz3,P31016,1.01087,NO,360,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.431,-3.198,1.767,5.09284,,,,,14.2425,1.419,,86.88,HHP,-1.52667,0.0758425,0.000770471,1.01087 kka2_1:2_E231C,kka2_1:2_231,Kka2,kka2_1:2,P00552,1.01088,NO,231,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.002,-3.282,1.28,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.295029,0.00732383,1.01088 beta-lactamase_39_G240D,beta-lactamase_39_240,TEM-1,beta-lactamase_39,P62593,1.01089,NO,240,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.0495842,0.00591201,1.01089 beta-lactamase_S233S,beta-lactamase_233,TEM-1,beta-lactamase,P62593,1.01089,NO,233,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.886,-1.886,,4.98121,0.016,E,B,0.48,-1.01,5.361,,77.62,BPO,-1.17267,0.221079,0.00311415,1.01089 beta-lactamase_39_R92A,beta-lactamase_39_92,TEM-1,beta-lactamase_39,P62593,1.0109,NO,92,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.718,-2.705,0.987,,0.479,E,B,1.2,1.36,0.389,,65.38,BBH,-1.50367,0.0495842,0.00429626,1.0109 beta-lactamase_625_E272Q,beta-lactamase_625_272,TEM-1,beta-lactamase_625,P62593,1.0109,NO,272,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.213352,0.00545371,1.0109 beta-lactamase_156_L38D,beta-lactamase_156_38,TEM-1,beta-lactamase_156,P62593,1.01091,NO,38,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.343,-3.97,2.627,,0.088,H,A,0.55,0.2,13.556,13.556,64.34,PHO,-1.78033,0.111618,0.00373244,1.01091 beta-lactamase_39_A246I,beta-lactamase_39_246,TEM-1,beta-lactamase_39,P62593,1.01091,NO,246,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.121,-2.179,0.058,,0.01,E,B,0.46,-1.01,1.331,,73.78,HHH,-1.55633,0.0495842,0.00569458,1.01091 beta-lactamase_H94T,beta-lactamase_94,TEM-1,beta-lactamase,P62593,1.01091,NO,94,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-2.5,-2.6,0.1,6.1507,0.776,,B,0.63,1.24,1.176,,77.62,HBH,-1.872,0.221079,0.00389226,1.01091 beta-lactamase_39_I277T,beta-lactamase_39_277,TEM-1,beta-lactamase_39,P62593,1.01092,NO,277,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.0495842,0.0169305,1.01092 beta-lactamase_625_E238D,beta-lactamase_625_238,TEM-1,beta-lactamase_625,P62593,1.01092,NO,238,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.213352,0.00743256,1.01092 beta-lactamase_A200G,beta-lactamase_200,TEM-1,beta-lactamase,P62593,1.01092,NO,200,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.878,-2.76,0.882,5.19406,0.757,H,A,0.47,-0.19,0.436,,77.62,HHP,-2.001,0.221079,0.0060056,1.01092 Pab1_A178H,Pab1_178,Pab1,Pab1,P04147,1.01092,NO,178,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.579,-4.56,2.981,,0.019,H,A,0.64,0.64,2.7,,81.63,OHH,-1.61067,0.175299,0.00160192,1.01092 beta-lactamase_156_E238Q,beta-lactamase_156_238,TEM-1,beta-lactamase_156,P62593,1.01093,NO,238,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.111618,0.00743256,1.01093 beta-lactamase_156_T112Y,beta-lactamase_156_112,TEM-1,beta-lactamase_156,P62593,1.01093,NO,112,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.186,-4.422,2.236,,0.921,T,A,0.22,1.06,2.87,,73.78,HPA,-1.925,0.111618,0.00531334,1.01093 beta-lactamase_625_T131G,beta-lactamase_625_131,TEM-1,beta-lactamase_625,P62593,1.01093,NO,131,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.328,-3.298,1.97,,,H,A,0.22,-0.69,2.031,,67.48,PPH,-1.00867,0.213352,0.00345886,1.01093 beta-lactamase_156_E166A,beta-lactamase_156_166,TEM-1,beta-lactamase_156,P62593,1.01094,NO,166,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.756,-2.056,0.3,,0.508,G,A,1.04,1.05,2.393,,73.08,OAH,-1.42233,0.111618,0.00512989,1.01094 beta-lactamase_156_P172M,beta-lactamase_156_172,TEM-1,beta-lactamase_156,P62593,1.01094,NO,172,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.998,-4.616,3.618,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.111618,0.00312594,1.01094 beta-lactamase_2500_A282M,beta-lactamase_2500_282,TEM-1,beta-lactamase_2500,P62593,1.01095,NO,282,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.361275,0.0449821,1.01095 beta-lactamase_2500_S122E,beta-lactamase_2500_122,TEM-1,beta-lactamase_2500,P62593,1.01095,NO,122,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.406,-2.103,-0.303,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.361275,0.00497825,1.01095 beta-lactamase_156_R202V,beta-lactamase_156_202,TEM-1,beta-lactamase_156,P62593,1.01096,NO,202,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.292,-3.679,2.387,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.111618,0.00321899,1.01096 beta-lactamase_156_T112F,beta-lactamase_156_112,TEM-1,beta-lactamase_156,P62593,1.01096,NO,112,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.186,-4.382,2.196,,0.921,T,A,0.22,1.06,2.87,,73.78,HPA,-1.925,0.111618,0.00531334,1.01096 beta-lactamase_156_Y103T,beta-lactamase_156_103,TEM-1,beta-lactamase_156,P62593,1.01096,NO,103,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-1.33,-3.696,2.366,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.111618,0.00443048,1.01096 beta-lactamase_625_A124V,beta-lactamase_625_124,TEM-1,beta-lactamase_625,P62593,1.01096,NO,124,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.181,-2.519,1.338,,,H,A,0.46,-0.9,2.027,,64.34,HHH,-1.152,0.213352,0.00481399,1.01096 beta-lactamase_625_A84I,beta-lactamase_625_84,TEM-1,beta-lactamase_625,P62593,1.01096,NO,84,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.651,-3.932,2.281,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.213352,0.00503822,1.01096 PSD95pdz3_T385D,PSD95pdz3_385,PSD95pdz3,PSD95pdz3,P31016,1.01096,NO,385,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.533,-3.15,1.617,5.57157,,,,,23.6871,4.527,,87.71,PPH,-1.56567,0.0758425,0.000545119,1.01096 beta-lactamase_156_E210F,beta-lactamase_156_210,TEM-1,beta-lactamase_156,P62593,1.01097,NO,210,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.319,-4.128,1.809,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.111618,0.00663582,1.01097 beta-lactamase_39_G216I,beta-lactamase_39_216,TEM-1,beta-lactamase_39,P62593,1.01097,NO,216,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.477,-4.183,2.706,,0.437,I,A,0.29,-0.58,0.834,,74.48,HOO,-1.68067,0.0495842,0.00639568,1.01097 beta-lactamase_39_A133G,beta-lactamase_39_133,TEM-1,beta-lactamase_39,P62593,1.01098,NO,133,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.186,-1.519,0.333,,,H,A,0.46,-0.86,0.373,,67.83,HHP,-0.988333,0.0495842,0.00468022,1.01098 PSD95pdz3_V386P,PSD95pdz3_386,PSD95pdz3,PSD95pdz3,P31016,1.01099,NO,386,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.465,-3.561,2.096,5.18836,,,,,17.5429,,,,PHP,-1.463,0.0758425,0.000184509,1.01099 beta-lactamase_2500_R189W,beta-lactamase_2500_189,TEM-1,beta-lactamase_2500,P62593,1.011,NO,189,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.844,-5.37,3.526,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.361275,0.0050699,1.011 beta-lactamase_39_A170P,beta-lactamase_39_170,TEM-1,beta-lactamase_39,P62593,1.011,NO,170,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.237,-3.899,2.662,,0.126,,L,0.46,-0.35,3.7,,64.69,AHH,-1.63267,0.0495842,0.00431903,1.011 beta-lactamase_625_H110L,beta-lactamase_625_110,TEM-1,beta-lactamase_625,P62593,1.011,NO,110,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-1.706,-3.515,1.809,,0.341,G,a,0.17,1.08,31.31,31.31,64.69,BBH,-1.73333,0.213352,0.00441499,1.011 beta-lactamase_K190R,beta-lactamase_190,TEM-1,beta-lactamase,P62593,1.011,NO,190,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.994,-2.302,0.308,5.49163,0.371,H,A,1.82,0.16,29.753,29.753,77.62,BBH,-1.64167,0.221079,0.00574527,1.011 beta-lactamase_39_P143M,beta-lactamase_39_143,TEM-1,beta-lactamase_39,P62593,1.01101,NO,143,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.967,-4.554,3.587,,0.075,H,A,0.52,-0.37,0.976,,66.78,OOB,-1.354,0.0495842,0.00114551,1.01101 beta-lactamase_625_A148W,beta-lactamase_625_148,TEM-1,beta-lactamase_625,P62593,1.01101,NO,148,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.757,-5.497,3.74,,0.379,H,A,0.46,-0.55,1.359,,72.73,PHH,-1.40167,0.213352,0.00547053,1.01101 beta-lactamase_D161D,beta-lactamase_161,TEM-1,beta-lactamase,P62593,1.01101,NO,161,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.891,-0.891,,5.12208,0.341,,A,0.23,-0.52,1.602,,61.19,HAB,-0.961333,0.221079,0.000897697,1.01101 beta-lactamase_Y95F,beta-lactamase_95,TEM-1,beta-lactamase,P62593,1.01101,NO,95,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-1.715,-2.096,0.381,5.67068,0.122,,b,0.96,-0.37,2.341,,77.62,BHP,-2.16167,0.221079,0.00479449,1.01101 beta-lactamase_156_K190R,beta-lactamase_156_190,TEM-1,beta-lactamase_156,P62593,1.01102,NO,190,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.994,-2.302,0.308,,0.371,H,A,2.34,0.16,1.513,,77.62,BBH,-1.64167,0.111618,0.00574527,1.01102 beta-lactamase_156_I140L,beta-lactamase_156_140,TEM-1,beta-lactamase_156,P62593,1.01103,NO,140,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.733,-1.622,-0.111,,0.128,H,A,0.48,0.41,1.16,,73.08,PHO,-1.48733,0.111618,0.00597777,1.01103 beta-lactamase_156_M180D,beta-lactamase_156_180,TEM-1,beta-lactamase_156,P62593,1.01103,NO,180,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-2.795,-3.594,0.799,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.111618,0.00552048,1.01103 beta-lactamase_2500_A182G,beta-lactamase_2500_182,TEM-1,beta-lactamase_2500,P62593,1.01104,NO,182,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.777,-3.408,1.631,,0.136,H,A,0.46,-0.66,2.032,,93.01,OHH,-1.27367,0.361275,0.00559099,1.01104 beta-lactamase_625_A222F,beta-lactamase_625_222,TEM-1,beta-lactamase_625,P62593,1.01104,NO,222,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.103,-4.23,2.127,,0.233,H,A,0.46,-0.25,1.448,,77.62,PHH,-1.63733,0.213352,0.00466094,1.01104 beta-lactamase_0_G52K,beta-lactamase_0_52,TEM-1,beta-lactamase_0,P62593,1.01105,NO,52,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.149,-3.631,2.482,,0.299,,l,0.29,-0.04,1.164,,64.69,POB,-1.66267,0.0500837,0.00340138,1.01105 beta-lactamase_2500_A84N,beta-lactamase_2500_84,TEM-1,beta-lactamase_2500,P62593,1.01105,NO,84,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.651,-2.768,1.117,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.361275,0.00503822,1.01105 beta-lactamase_625_R275S,beta-lactamase_625_275,TEM-1,beta-lactamase_625,P62593,1.01105,NO,275,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.213352,0.0141984,1.01105 beta-lactamase_H151R,beta-lactamase_151,TEM-1,beta-lactamase,P62593,1.01105,NO,151,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-2.96,-1.217,-1.743,5.47408,0.594,H,A,0.35,0.1,1.843,,77.62,HBP,-2.34767,0.221079,0.00216946,1.01105 beta-lactamase_625_H110A,beta-lactamase_625_110,TEM-1,beta-lactamase_625,P62593,1.01106,NO,110,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-1.706,-3.353,1.647,,0.341,G,a,0.17,1.08,31.31,31.31,64.69,BBH,-1.73333,0.213352,0.00441499,1.01106 kka2_1:2_L123R,kka2_1:2_123,Kka2,kka2_1:2,P00552,1.01106,NO,123,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.888,-4.001,3.113,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.295029,0.00325188,1.01106 beta-lactamase_39_K32A,beta-lactamase_39_32,TEM-1,beta-lactamase_39,P62593,1.01107,NO,32,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.984,-2.363,0.379,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.0495842,0.00401283,1.01107 beta-lactamase_156_V42C,beta-lactamase_156_42,TEM-1,beta-lactamase_156,P62593,1.01109,NO,42,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.564,-4.789,3.225,,0.017,E,B,0.44,-0.51,2.576,,63.99,BHO,-1.042,0.111618,0.00404515,1.01109 beta-lactamase_2500_S96G,beta-lactamase_2500_96,TEM-1,beta-lactamase_2500,P62593,1.01109,NO,96,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.27,-2.481,0.211,,0.368,,b,0.27,0.39,32.348,32.348,73.78,HPP,-2.019,0.361275,0.00551835,1.01109 beta-lactamase_625_I54P,beta-lactamase_625_54,TEM-1,beta-lactamase_625,P62593,1.01109,NO,54,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-2.838,-4.045,1.207,,0.669,E,B,0.48,-0.14,3.946,,73.78,BHH,-2.337,0.213352,0.00403589,1.01109 beta-lactamase_625_V29K,beta-lactamase_625_29,TEM-1,beta-lactamase_625,P62593,1.01109,NO,29,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-2.856,-2.195,-0.661,,0.733,H,A,0.44,-0.78,1.931,,93.01,HHB,-2.24733,0.213352,0.00318969,1.01109 beta-lactamase_156_K190E,beta-lactamase_156_190,TEM-1,beta-lactamase_156,P62593,1.0111,NO,190,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.994,-3.44,1.446,,0.371,H,A,2.34,0.16,1.513,,77.62,BBH,-1.64167,0.111618,0.00574527,1.0111 beta-lactamase_156_L192I,beta-lactamase_156_192,TEM-1,beta-lactamase_156,P62593,1.0111,NO,192,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.254,-2.519,1.265,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.111618,0.00558728,1.0111 beta-lactamase_156_T116E,beta-lactamase_156_116,TEM-1,beta-lactamase_156,P62593,1.0111,NO,116,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.28,-3.469,2.189,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.111618,0.00336175,1.0111 beta-lactamase_0_N152K,beta-lactamase_0_152,TEM-1,beta-lactamase_0,P62593,1.01111,NO,152,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-2.757,-2.892,0.135,,0.863,H,A,0.61,0.92,2.151,,77.62,BPH,-2.97,0.0500837,0.00471429,1.01111 beta-lactamase_156_R118D,beta-lactamase_156_118,TEM-1,beta-lactamase_156,P62593,1.01111,NO,118,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.413,-2.866,0.453,,0.457,H,A,1.2,1.39,2.231,,77.62,HBA,-1.785,0.111618,0.00538794,1.01111 beta-lactamase_156_Y44I,beta-lactamase_156_44,TEM-1,beta-lactamase_156,P62593,1.01111,NO,44,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-2.547,-2.364,-0.183,,,E,B,0.21,-0.45,2.184,,73.78,OHH,-1.86267,0.111618,0.00426364,1.01111 beta-lactamase_39_P165F,beta-lactamase_39_165,TEM-1,beta-lactamase_39,P62593,1.01111,NO,165,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.373,-4.322,2.949,,0.203,T,A,0.52,-0.31,3.907,,73.78,AOA,-1.359,0.0495842,0.00549538,1.01111 beta-lactamase_625_P105T,beta-lactamase_625_105,TEM-1,beta-lactamase_625,P62593,1.01111,NO,105,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.813,-3.385,2.572,,0.226,T,A,0.52,0.8,1.154,,63.29,POH,-1.01533,0.213352,0.0011981,1.01111 beta-lactamase_156_I261L,beta-lactamase_156_261,TEM-1,beta-lactamase_156,P62593,1.01113,NO,261,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.111618,0.0123091,1.01113 beta-lactamase_156_T139Q,beta-lactamase_156_139,TEM-1,beta-lactamase_156,P62593,1.01113,NO,139,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.901,-2.8,0.899,,0.216,H,A,0.22,0.39,16.34,16.34,77.62,PPH,-2.04667,0.111618,0.00441837,1.01113 beta-lactamase_39_T147R,beta-lactamase_39_147,TEM-1,beta-lactamase_39,P62593,1.01113,NO,147,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.149,-3.809,2.66,,0.281,H,A,0.22,-0.68,13.843,13.843,64.34,HPH,-1.456,0.0495842,0.00226017,1.01113 beta-lactamase_625_E238R,beta-lactamase_625_238,TEM-1,beta-lactamase_625,P62593,1.01113,NO,238,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.002,-3.465,1.463,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.213352,0.00743256,1.01113 beta-lactamase_39_G154K,beta-lactamase_39_154,TEM-1,beta-lactamase_39,P62593,1.01114,NO,154,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.823,-3.683,2.86,,0.54,T,l,0.29,-0.56,1.151,,64.69,HOA,-1.635,0.0495842,0.00180205,1.01114 beta-lactamase_156_I280M,beta-lactamase_156_280,TEM-1,beta-lactamase_156,P62593,1.01115,NO,280,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.111618,0.0530888,1.01115 beta-lactamase_156_S51M,beta-lactamase_156_51,TEM-1,beta-lactamase_156,P62593,1.01115,NO,51,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.526,-4.705,3.179,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.111618,0.00504821,1.01115 beta-lactamase_39_T116C,beta-lactamase_39_116,TEM-1,beta-lactamase_39,P62593,1.01115,NO,116,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.28,-4.831,3.551,,0.115,E,B,0.22,-0.12,1.133,,67.48,HPH,-1.39967,0.0495842,0.00336175,1.01115 beta-lactamase_P217P,beta-lactamase_217,TEM-1,beta-lactamase,P62593,1.01116,NO,217,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-2.062,-2.062,,5.19872,0.496,I,A,0.99,-0.33,0.431,,74.48,OOH,-1.64333,0.221079,0.00463211,1.01116 kka2_1:8_A41F,kka2_1:8_41,Kka2,kka2_1:8,P00552,1.01116,NO,41,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.879,-3.42,1.541,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.100394,0.00543332,1.01116 kka2_1:8_A41F,kka2_1:8_41,Kka2,kka2_1:8,P00552,1.01116,NO,41,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.879,-3.42,1.541,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.100394,0.00543332,1.01116 beta-lactamase_39_R63G,beta-lactamase_39_63,TEM-1,beta-lactamase_39,P62593,1.01117,NO,63,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-0.943,-3.426,2.483,,0.218,,B,1.2,-0.31,0.326,,44.06,ABH,-0.992333,0.0495842,0.00126938,1.01117 beta-lactamase_625_K109R,beta-lactamase_625_109,TEM-1,beta-lactamase_625,P62593,1.01117,NO,109,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.734,-2.595,0.861,,0.787,G,A,2.34,2.21,7.243,,72.73,ABB,-1.63333,0.213352,0.00462493,1.01117 beta-lactamase_625_M67Q,beta-lactamase_625_67,TEM-1,beta-lactamase_625,P62593,1.01117,NO,67,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-2.231,-4.09,1.859,,0.006,G,P,0.55,-0.81,2.653,,65.03,HHP,-1.502,0.213352,0.00409753,1.01117 beta-lactamase_625_R275Y,beta-lactamase_625_275,TEM-1,beta-lactamase_625,P62593,1.01117,NO,275,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.213352,0.0141984,1.01117 beta-lactamase_39_T186L,beta-lactamase_39_186,TEM-1,beta-lactamase_39,P62593,1.01118,NO,186,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.522,-2.882,0.36,,0.396,H,A,0.22,-0.28,0.515,,77.62,HPP,-1.77633,0.0495842,0.00485034,1.01118 beta-lactamase_A148L,beta-lactamase_148,TEM-1,beta-lactamase,P62593,1.01118,NO,148,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.757,-3.596,1.839,5.28111,0.379,H,A,0.52,-0.55,2.117,,72.73,PHH,-1.40167,0.221079,0.00547053,1.01118 beta-lactamase_A280D,beta-lactamase_280,TEM-1,beta-lactamase,P62593,1.01118,NO,280,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.708,-2.796,1.088,4.74932,0.379,H,A,0.52,-0.72,1.785,,68.18,OHP,-1.66433,0.221079,0.0530888,1.01118 beta-lactamase_D113T,beta-lactamase_113,TEM-1,beta-lactamase,P62593,1.01118,NO,113,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.829,-2.544,0.715,6.04499,0.665,T,A,0.23,0.91,21.104,21.104,73.08,PAO,-1.703,0.221079,0.00474112,1.01118 beta-lactamase_G39A,beta-lactamase_39,TEM-1,beta-lactamase,P62593,1.01118,NO,39,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.864,-2.728,0.864,5.35574,0.701,T,L,0.23,0.47,29.926,29.926,77.62,HOH,-1.53633,0.221079,0.00487611,1.01118 beta-lactamase_H94M,beta-lactamase_94,TEM-1,beta-lactamase,P62593,1.01118,NO,94,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-2.5,-3.474,0.974,6.1507,0.776,,B,0.63,1.24,1.176,,77.62,HBH,-1.872,0.221079,0.00389226,1.01118 beta-lactamase_I54L,beta-lactamase_54,TEM-1,beta-lactamase,P62593,1.01118,NO,54,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-2.838,-2.471,-0.367,5.40541,0.669,E,B,0.77,-0.14,3.946,,73.78,BHH,-2.337,0.221079,0.00403589,1.01118 beta-lactamase_K109G,beta-lactamase_109,TEM-1,beta-lactamase,P62593,1.01118,NO,109,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.734,-2.852,1.118,6.05842,0.787,G,A,1.82,2.21,21.623,21.623,72.73,ABB,-1.63333,0.221079,0.00462493,1.01118 beta-lactamase_K284Y,beta-lactamase_284,TEM-1,beta-lactamase,P62593,1.01118,NO,284,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.981,-4.228,2.247,6.30084,0.848,H,A,1.82,0.67,1.931,,77.62,HBB,-1.82133,0.221079,0.0686156,1.01118 beta-lactamase_L199Q,beta-lactamase_199,TEM-1,beta-lactamase,P62593,1.01118,NO,199,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-2.942,-3.22,0.278,5.57712,0.832,H,A,0.82,0.42,15.302,15.302,77.62,PHH,-2.32933,0.221079,0.0048649,1.01118 beta-lactamase_N173R,beta-lactamase_173,TEM-1,beta-lactamase,P62593,1.01118,NO,173,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-2.663,-3.837,1.174,7.02497,1.044,T,l,0.09,1.25,1.88,,77.62,OPA,-1.46633,0.221079,0.0033769,1.01118 beta-lactamase_P20K,beta-lactamase_20,TEM-1,beta-lactamase,P62593,1.01118,NO,20,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.74,-3.434,1.694,,,,,,,0.368,,67.83,HOH,-1.765,0.221079,0.00235322,1.01118 beta-lactamase_Q204C,beta-lactamase_204,TEM-1,beta-lactamase,P62593,1.01118,NO,204,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-1.382,-5.114,3.732,5.46394,0.204,H,A,0.12,0.09,1.707,,66.08,PPH,-1.49067,0.221079,0.00364106,1.01118 beta-lactamase_Q37F,beta-lactamase_37,TEM-1,beta-lactamase,P62593,1.01118,NO,37,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.134,-4.314,2.18,5.69153,0.613,H,A,0.12,1.98,1.318,,73.08,APH,-2.06967,0.221079,0.00425833,1.01118 beta-lactamase_T193H,beta-lactamase_193,TEM-1,beta-lactamase,P62593,1.01118,NO,193,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.914,-4.78,2.866,5.67952,0.439,H,a,0.3,0.33,1.863,,63.99,HPO,-1.52133,0.221079,0.00482669,1.01118 beta-lactamase_V157Q,beta-lactamase_157,TEM-1,beta-lactamase,P62593,1.01118,NO,157,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.751,-4.045,2.294,5.51733,0.308,S,a,0.96,-0.75,1.847,,69.58,BHP,-2.00767,0.221079,0.00506849,1.01118 beta-lactamase_625_T186L,beta-lactamase_625_186,TEM-1,beta-lactamase_625,P62593,1.01119,NO,186,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.522,-2.882,0.36,,0.396,H,A,0.22,-0.28,0.515,,77.62,HPP,-1.77633,0.213352,0.00485034,1.01119 gb1_A250D,gb1_250,gb1,gb1,P06654,1.01119,NO,250,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.713,-3.123,1.41,,,,,,,3.465,,45.54,HHP,-1.74867,0.177985,0.00332003,1.01119 kka2_1:8_E169F,kka2_1:8_169,Kka2,kka2_1:8,P00552,1.01119,NO,169,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.996,-3.429,1.433,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.100394,0.00730086,1.01119 kka2_1:8_E169F,kka2_1:8_169,Kka2,kka2_1:8,P00552,1.01119,NO,169,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.996,-3.429,1.433,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.100394,0.00730086,1.01119 beta-lactamase_625_G216Q,beta-lactamase_625_216,TEM-1,beta-lactamase_625,P62593,1.0112,NO,216,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.477,-3.862,2.385,,0.437,I,A,0.29,-0.58,1.718,,74.48,HOO,-1.68067,0.213352,0.00639568,1.0112 beta-lactamase_156_A170W,beta-lactamase_156_170,TEM-1,beta-lactamase_156,P62593,1.01121,NO,170,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.237,-5.233,3.996,,0.126,,L,0.46,-0.35,3.7,,64.69,AHH,-1.63267,0.111618,0.00431903,1.01121 beta-lactamase_2500_Q86Y,beta-lactamase_2500_86,TEM-1,beta-lactamase_2500,P62593,1.01121,NO,86,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.4,-4.372,1.972,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.361275,0.00450027,1.01121 beta-lactamase_625_L73Y,beta-lactamase_625_73,TEM-1,beta-lactamase_625,P62593,1.01121,NO,73,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.507,-3.917,2.41,,,H,A,0.55,-0.64,2.933,,67.83,HHH,-1.487,0.213352,0.00488983,1.01121 kka2_1:4_H124T,kka2_1:4_124,Kka2,kka2_1:4,P00552,1.01121,NO,124,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-0.84,-3.675,2.835,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.168804,0.00211296,1.01121 beta-lactamase_156_E279H,beta-lactamase_156_279,TEM-1,beta-lactamase_156,P62593,1.01122,NO,279,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.111618,0.0192826,1.01122 beta-lactamase_39_P250I,beta-lactamase_39_250,TEM-1,beta-lactamase_39,P62593,1.01122,NO,250,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.0495842,0.00550899,1.01122 beta-lactamase_156_L248I,beta-lactamase_156_248,TEM-1,beta-lactamase_156,P62593,1.01123,NO,248,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.111618,0.00428493,1.01123 beta-lactamase_39_P217N,beta-lactamase_39_217,TEM-1,beta-lactamase_39,P62593,1.01123,NO,217,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-2.062,-2.997,0.935,,0.496,I,A,0.52,-0.33,21.172,21.172,74.48,OOH,-1.64333,0.0495842,0.00463211,1.01123 beta-lactamase_625_D36E,beta-lactamase_625_36,TEM-1,beta-lactamase_625,P62593,1.01123,NO,36,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.732,-2.66,-0.072,,0.555,H,A,0.75,1.17,2.26,,77.62,AAP,-1.91167,0.213352,0.00476483,1.01123 beta-lactamase_625_G226E,beta-lactamase_625_226,TEM-1,beta-lactamase_625,P62593,1.01123,NO,226,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.461,-2.776,1.315,,0.701,T,l,0.29,-0.25,3.199,,74.48,HOH,-1.42933,0.213352,0.00665294,1.01123 beta-lactamase_625_L150F,beta-lactamase_625_150,TEM-1,beta-lactamase_625,P62593,1.01123,NO,150,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.326,-3.884,2.558,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.213352,0.00463171,1.01123 beta-lactamase_2500_S80N,beta-lactamase_2500_80,TEM-1,beta-lactamase_2500,P62593,1.01124,NO,80,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.029,-2.999,0.97,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.361275,0.00565569,1.01124 beta-lactamase_625_K144H,beta-lactamase_625_144,TEM-1,beta-lactamase_625,P62593,1.01124,NO,144,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-2.388,-3.395,1.007,,0.863,H,A,2.34,1.27,2.313,,77.62,OBA,-1.904,0.213352,0.00481141,1.01124 PSD95pdz3_K355H,PSD95pdz3_355,PSD95pdz3,PSD95pdz3,P31016,1.01124,NO,355,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.416,-4.137,2.721,5.56865,,,,,17.2556,,,,BBO,-1.33533,0.0758425,0.00063703,1.01124 beta-lactamase_39_Q267L,beta-lactamase_39_267,TEM-1,beta-lactamase_39,P62593,1.01125,NO,267,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.0495842,0.0102128,1.01125 beta-lactamase_156_F228H,beta-lactamase_156_228,TEM-1,beta-lactamase_156,P62593,1.01126,NO,228,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-2.342,-3.331,0.989,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.111618,0.0046669,1.01126 beta-lactamase_2500_F58W,beta-lactamase_2500_58,TEM-1,beta-lactamase_2500,P62593,1.01126,NO,58,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-2.914,-2.275,-0.639,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.361275,0.00523369,1.01126 beta-lactamase_39_H151K,beta-lactamase_39_151,TEM-1,beta-lactamase_39,P62593,1.01126,NO,151,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-2.96,-3.032,0.072,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.0495842,0.00216946,1.01126 kka2_1:1_A9P,kka2_1:1_9,Kka2,kka2_1:1,P00552,1.01126,NO,9,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.079,-2.571,0.492,,,,,,,0.383,,71.59,BHO,-2.253,0.520039,0.00273264,1.01126 PSD95pdz3_A378C,PSD95pdz3_378,PSD95pdz3,PSD95pdz3,P31016,1.01126,NO,378,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.307,-4.094,2.787,4.86582,,,,,14.576,,,,HHH,-1.509,0.0758425,0.000313169,1.01126 beta-lactamase_156_L150A,beta-lactamase_156_150,TEM-1,beta-lactamase_156,P62593,1.01128,NO,150,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.326,-2.051,0.725,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.111618,0.00463171,1.01128 beta-lactamase_156_R220G,beta-lactamase_156_220,TEM-1,beta-lactamase_156,P62593,1.01128,NO,220,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-0.942,-3.321,2.379,,0.295,I,A,1.2,-0.76,2.164,,74.48,HBP,-1.33633,0.111618,0.00232421,1.01128 beta-lactamase_625_G39V,beta-lactamase_625_39,TEM-1,beta-lactamase_625,P62593,1.01128,NO,39,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.864,-3.813,1.949,,0.701,T,L,0.29,0.47,29.926,29.926,77.62,HOH,-1.53633,0.213352,0.00487611,1.01128 beta-lactamase_E166L,beta-lactamase_166,TEM-1,beta-lactamase,P62593,1.01128,NO,166,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.756,-2.872,1.116,5.60527,0.508,G,A,0.52,1.05,2.124,,73.08,OAH,-1.42233,0.221079,0.00512989,1.01128 beta-lactamase_E175A,beta-lactamase_175,TEM-1,beta-lactamase,P62593,1.01128,NO,175,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.336,-2.1,-0.236,6.0311,0.551,,A,0.75,1.05,5.316,,77.62,AAB,-1.31233,0.221079,0.00482205,1.01128 beta-lactamase_625_A84Y,beta-lactamase_625_84,TEM-1,beta-lactamase_625,P62593,1.01129,NO,84,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.651,-4.29,2.639,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.213352,0.00503822,1.01129 kka2_1:8_L123I,kka2_1:8_123,Kka2,kka2_1:8,P00552,1.01129,NO,123,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.888,-2.453,1.565,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.100394,0.00325188,1.01129 kka2_1:8_L123I,kka2_1:8_123,Kka2,kka2_1:8,P00552,1.01129,NO,123,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.888,-2.453,1.565,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.100394,0.00325188,1.01129 beta-lactamase_156_G194H,beta-lactamase_156_194,TEM-1,beta-lactamase_156,P62593,1.0113,NO,194,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.396,-4.628,3.232,,0.276,S,b,0.29,0.36,1.346,,67.83,POA,-1.832,0.111618,0.00392163,1.0113 beta-lactamase_39_E238G,beta-lactamase_39_238,TEM-1,beta-lactamase_39,P62593,1.01131,NO,238,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.0495842,0.00743256,1.01131 beta-lactamase_39_H151W,beta-lactamase_39_151,TEM-1,beta-lactamase_39,P62593,1.01131,NO,151,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-2.96,-5.334,2.374,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.0495842,0.00216946,1.01131 beta-lactamase_39_H24F,beta-lactamase_39_24,TEM-1,beta-lactamase_39,P62593,1.01131,NO,24,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-2.481,-4.152,1.671,,,,,,,2.708,,93.01,OBO,-2.0035,0.0495842,0.00238894,1.01131 beta-lactamase_625_L188M,beta-lactamase_625_188,TEM-1,beta-lactamase_625,P62593,1.01131,NO,188,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.166,-2.706,1.54,,,H,A,0.55,-0.3,2.982,,60.14,PHB,-1.47033,0.213352,0.00295687,1.01131 beta-lactamase_E175Q,beta-lactamase_175,TEM-1,beta-lactamase,P62593,1.01132,NO,175,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.336,-3.092,0.756,6.0311,0.551,,A,0.75,1.05,5.316,,77.62,AAB,-1.31233,0.221079,0.00482205,1.01132 beta-lactamase_T186G,beta-lactamase_186,TEM-1,beta-lactamase,P62593,1.01132,NO,186,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.522,-2.403,-0.119,5.07364,0.396,H,A,0.3,-0.28,2.144,,77.62,HPP,-1.77633,0.221079,0.00485034,1.01132 beta-lactamase_0_E62N,beta-lactamase_0_62,TEM-1,beta-lactamase_0,P62593,1.01133,NO,62,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.193,-3.541,2.348,,0.342,S,B,1.04,-0.3,5.784,,73.08,AAB,-1.417,0.0500837,0.00264802,1.01133 beta-lactamase_0_L223R,beta-lactamase_0_223,TEM-1,beta-lactamase_0,P62593,1.01133,NO,223,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.055,-4.022,2.967,,0.27,,B,0.55,0.09,1.633,,74.48,HHO,-1.35033,0.0500837,0.00372793,1.01133 beta-lactamase_156_D99A,beta-lactamase_156_99,TEM-1,beta-lactamase_156,P62593,1.01133,NO,99,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.191,-2.613,1.422,,0.402,G,A,0.75,0.36,3.529,,64.69,PAH,-1.794,0.111618,0.00305446,1.01133 beta-lactamase_156_V260G,beta-lactamase_156_260,TEM-1,beta-lactamase_156,P62593,1.01133,NO,260,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.111618,0.00471757,1.01133 beta-lactamase_39_I140C,beta-lactamase_39_140,TEM-1,beta-lactamase_39,P62593,1.01133,NO,140,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.733,-4.792,3.059,,0.128,H,A,0.48,0.41,1.16,,73.08,PHO,-1.48733,0.0495842,0.00597777,1.01133 beta-lactamase_39_T126V,beta-lactamase_39_126,TEM-1,beta-lactamase_39,P62593,1.01133,NO,126,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.122,-3.336,2.214,,0.05,H,A,0.22,-0.05,0.586,,44.41,HPH,-1.60467,0.0495842,0.00244552,1.01133 beta-lactamase_0_K286Q,beta-lactamase_0_286,TEM-1,beta-lactamase_0,P62593,1.01134,NO,286,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.0500837,,1.01134 beta-lactamase_39_L160T,beta-lactamase_39_160,TEM-1,beta-lactamase_39,P62593,1.01134,NO,160,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.977,-3.438,2.461,,0.022,,B,0.55,-0.6,0.895,,44.41,BHA,-0.936,0.0495842,0.00193775,1.01134 beta-lactamase_625_E210Y,beta-lactamase_625_210,TEM-1,beta-lactamase_625,P62593,1.01134,NO,210,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.319,-4.214,1.895,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.213352,0.00663582,1.01134 beta-lactamase_625_Q97Y,beta-lactamase_625_97,TEM-1,beta-lactamase_625,P62593,1.01134,NO,97,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.072,-4.35,2.278,,0.823,G,A,0.64,2.42,16.954,16.954,77.62,PPP,-2.43833,0.213352,0.0045116,1.01134 PSD95pdz3_N369T,PSD95pdz3_369,PSD95pdz3,PSD95pdz3,P31016,1.01134,NO,369,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-1.572,-2.877,1.305,5.91569,,,,,24.1262,0.44,,87.71,BPH,-1.487,0.0758425,0.000608412,1.01134 beta-lactamase_156_R92Q,beta-lactamase_156_92,TEM-1,beta-lactamase_156,P62593,1.01135,NO,92,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.718,-3.029,1.311,,0.479,E,B,1.2,1.36,19.112,19.112,65.38,BBH,-1.50367,0.111618,0.00429626,1.01135 beta-lactamase_625_E108R,beta-lactamase_625_108,TEM-1,beta-lactamase_625,P62593,1.01135,NO,108,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.46,-2.885,1.425,,0.572,G,A,1.04,1.87,20.151,20.151,72.73,PAB,-1.437,0.213352,0.00413372,1.01135 beta-lactamase_2500_T186F,beta-lactamase_2500_186,TEM-1,beta-lactamase_2500,P62593,1.01136,NO,186,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.522,-4.342,1.82,,0.396,H,A,0.22,-0.28,2.144,,77.62,HPP,-1.77633,0.361275,0.00485034,1.01136 beta-lactamase_39_A235T,beta-lactamase_39_235,TEM-1,beta-lactamase_39,P62593,1.01136,NO,235,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.266,-2.412,1.146,,0.32,E,B,0.46,-0.86,1.344,,50,OHO,-0.89,0.0495842,0.00493474,1.01136 beta-lactamase_39_T27L,beta-lactamase_39_27,TEM-1,beta-lactamase_39,P62593,1.01136,NO,27,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.905,-2.65,0.745,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.0495842,0.00306559,1.01136 beta-lactamase_625_L160T,beta-lactamase_625_160,TEM-1,beta-lactamase_625,P62593,1.01136,NO,160,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.977,-3.438,2.461,,0.022,,B,0.55,-0.6,0.237,,44.41,BHA,-0.936,0.213352,0.00193775,1.01136 beta-lactamase_625_V82Q,beta-lactamase_625_82,TEM-1,beta-lactamase_625,P62593,1.01136,NO,82,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.325,-4.196,2.871,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.213352,0.00397046,1.01136 Pab1_A141S,Pab1_141,Pab1,Pab1,P04147,1.01136,NO,141,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.461,-2.141,0.68,,0.34,H,A,0.52,-0.27,2.15,,79.03,BHH,-1.19433,0.175299,0.00165974,1.01136 beta-lactamase_156_A170N,beta-lactamase_156_170,TEM-1,beta-lactamase_156,P62593,1.01137,NO,170,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.237,-2.833,1.596,,0.126,,L,0.46,-0.35,3.7,,64.69,AHH,-1.63267,0.111618,0.00431903,1.01137 beta-lactamase_156_E108F,beta-lactamase_156_108,TEM-1,beta-lactamase_156,P62593,1.01137,NO,108,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.46,-4.416,2.956,,0.572,G,A,1.04,1.87,8.602,8.602,72.73,PAB,-1.437,0.111618,0.00413372,1.01137 beta-lactamase_39_H156Y,beta-lactamase_39_156,TEM-1,beta-lactamase_39,P62593,1.01137,NO,156,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-3.156,-4.359,1.203,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.0495842,0.00468596,1.01137 beta-lactamase_625_E210M,beta-lactamase_625_210,TEM-1,beta-lactamase_625,P62593,1.01138,NO,210,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.319,-4.371,2.052,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.213352,0.00663582,1.01138 beta-lactamase_L135I,beta-lactamase_135,TEM-1,beta-lactamase,P62593,1.01138,NO,135,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.002,-2.037,1.035,5.28497,0.117,H,A,1.07,-0.58,0.697,,43.71,PHH,-1.03767,0.221079,0.00244423,1.01138 beta-lactamase_S51S,beta-lactamase_51,TEM-1,beta-lactamase,P62593,1.01138,NO,51,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.526,-1.526,,5.06164,0.496,T,A,0.25,0.26,1.699,,72.73,PPO,-1.88467,0.221079,0.00504821,1.01138 beta-lactamase_39_L79C,beta-lactamase_39_79,TEM-1,beta-lactamase_39,P62593,1.01139,NO,79,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.842,-4.663,3.821,,0.007,H,A,0.55,-0.16,0.823,,50.35,HHP,-1.44333,0.0495842,0.000947397,1.01139 beta-lactamase_156_R59H,beta-lactamase_156_59,TEM-1,beta-lactamase_156,P62593,1.0114,NO,59,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.345,-4.424,3.079,,0.329,S,L,1.2,-0.09,2.995,,73.08,HBO,-2.24267,0.111618,0.00318082,1.0114 beta-lactamase_625_A34Y,beta-lactamase_625_34,TEM-1,beta-lactamase_625,P62593,1.0114,NO,34,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.059,-4.077,2.018,,,H,A,0.46,-0.54,3.614,,73.78,AHA,-1.74967,0.213352,0.00407913,1.0114 beta-lactamase_625_P255Y,beta-lactamase_625_255,TEM-1,beta-lactamase_625,P62593,1.0114,NO,255,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.213352,0.00499612,1.0114 beta-lactamase_K53I,beta-lactamase_53,TEM-1,beta-lactamase,P62593,1.0114,NO,53,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-2.313,-4.015,1.702,5.93654,0.589,,B,1.82,1.15,19.72,19.72,77.62,OBH,-2.1,0.221079,0.00383383,1.0114 kka2_1:4_H139G,kka2_1:4_139,Kka2,kka2_1:4,P00552,1.0114,NO,139,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-2.809,-2.92,0.111,,0.471,H,A,0.17,0.68,12.761,12.761,63.64,BBB,-2.22,0.168804,0.00734779,1.0114 beta-lactamase_0_A124L,beta-lactamase_0_124,TEM-1,beta-lactamase_0,P62593,1.01141,NO,124,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.181,-3.172,1.991,,,H,A,0.46,-0.9,1.876,,64.34,HHH,-1.152,0.0500837,0.00481399,1.01141 beta-lactamase_156_V78H,beta-lactamase_156_78,TEM-1,beta-lactamase_156,P62593,1.01141,NO,78,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.459,-5.015,3.556,,,H,A,0.44,-0.47,1.132,,63.64,HHH,-1.17833,0.111618,0.00492501,1.01141 beta-lactamase_625_A278N,beta-lactamase_625_278,TEM-1,beta-lactamase_625,P62593,1.01141,NO,278,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.213352,0.0310297,1.01141 beta-lactamase_625_N50D,beta-lactamase_625_50,TEM-1,beta-lactamase_625,P62593,1.01141,NO,50,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-2.979,-2.468,-0.511,,0.912,T,A,0.61,1.24,3.446,,77.62,HPP,-2.134,0.213352,0.0047211,1.01141 beta-lactamase_625_A34S,beta-lactamase_625_34,TEM-1,beta-lactamase_625,P62593,1.01142,NO,34,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.059,-2.213,0.154,,,H,A,0.46,-0.54,3.614,,73.78,AHA,-1.74967,0.213352,0.00407913,1.01142 beta-lactamase_L146L,beta-lactamase_146,TEM-1,beta-lactamase,P62593,1.01142,NO,146,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.462,-1.462,,5.62483,0.007,H,A,1.3,-0.56,1.953,,64.69,AHP,-1.656,0.221079,0.00474542,1.01142 beta-lactamase_156_A34H,beta-lactamase_156_34,TEM-1,beta-lactamase_156,P62593,1.01143,NO,34,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.059,-4.883,2.824,,,H,A,0.46,-0.54,3.614,,73.78,AHA,-1.74967,0.111618,0.00407913,1.01143 beta-lactamase_39_G90M,beta-lactamase_39_90,TEM-1,beta-lactamase_39,P62593,1.01143,NO,90,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-2.091,-4.839,2.748,,0.598,T,A,0.29,0.32,30.794,30.794,77.62,HOB,-1.52633,0.0495842,0.00490273,1.01143 beta-lactamase_625_A282R,beta-lactamase_625_282,TEM-1,beta-lactamase_625,P62593,1.01143,NO,282,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.213352,0.0449821,1.01143 beta-lactamase_156_W208Y,beta-lactamase_156_208,TEM-1,beta-lactamase_156,P62593,1.01144,NO,208,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-0.818,-3.262,2.444,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.111618,0.00126609,1.01144 beta-lactamase_39_E238K,beta-lactamase_39_238,TEM-1,beta-lactamase_39,P62593,1.01146,NO,238,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.0495842,0.00743256,1.01146 beta-lactamase_39_V29D,beta-lactamase_39_29,TEM-1,beta-lactamase_39,P62593,1.01146,NO,29,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-2.856,-2.298,-0.558,,0.733,H,A,0.44,-0.78,1.287,,93.01,HHB,-2.24733,0.0495842,0.00318969,1.01146 beta-lactamase_H156N,beta-lactamase_156,TEM-1,beta-lactamase,P62593,1.01146,NO,156,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-3.156,-2.52,-0.636,6.00284,0.753,S,A,0.72,-0.6,6.456,6.456,77.62,ABH,-1.932,0.221079,0.00468596,1.01146 Pab1_D184E,Pab1_184,Pab1,Pab1,P04147,1.01146,NO,184,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.5,-1.402,-0.098,,,,,,,,,,HAH,-1.50133,0.175299,0.0011931,1.01146 beta-lactamase_156_G52V,beta-lactamase_156_52,TEM-1,beta-lactamase_156,P62593,1.01147,NO,52,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.149,-3.738,2.589,,0.299,,l,0.29,-0.04,1.179,,64.69,POB,-1.66267,0.111618,0.00340138,1.01147 beta-lactamase_39_V29I,beta-lactamase_39_29,TEM-1,beta-lactamase_39,P62593,1.01147,NO,29,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-2.856,-3.928,1.072,,0.733,H,A,0.44,-0.78,1.287,,93.01,HHB,-2.24733,0.0495842,0.00318969,1.01147 beta-lactamase_0_I261F,beta-lactamase_0_261,TEM-1,beta-lactamase_0,P62593,1.01148,NO,261,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.0500837,0.0123091,1.01148 beta-lactamase_156_L160I,beta-lactamase_156_160,TEM-1,beta-lactamase_156,P62593,1.01148,NO,160,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.977,-2.155,1.178,,0.022,,B,0.55,-0.6,1.095,,44.41,BHA,-0.936,0.111618,0.00193775,1.01148 beta-lactamase_156_L219C,beta-lactamase_156_219,TEM-1,beta-lactamase_156,P62593,1.01148,NO,219,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.313,-3.103,1.79,,,I,A,0.55,-0.51,2.321,,74.48,HHB,-1.21533,0.111618,0.00664345,1.01148 beta-lactamase_39_R159H,beta-lactamase_39_159,TEM-1,beta-lactamase_39,P62593,1.01148,NO,159,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-0.94,-2.789,1.849,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.0495842,0.00108472,1.01148 beta-lactamase_625_L135V,beta-lactamase_625_135,TEM-1,beta-lactamase_625,P62593,1.01148,NO,135,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.002,-2.8,1.798,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.213352,0.00244423,1.01148 hsp90_E590Q,hsp90_590,hsp90,hsp90,P02829,1.01148,NO,590,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.818,-3.278,0,4.65049,0.021,H,A,,0.03,,,,HAO,-3.338,0.368192,0.000222939,1.01148 PSD95pdz3_G351E,PSD95pdz3_351,PSD95pdz3,PSD95pdz3,P31016,1.01148,NO,351,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.008,-3.347,2.339,5.44798,,,,,20.7625,,,,POA,-1.37133,0.0758425,0.000691282,1.01148 beta-lactamase_39_M67V,beta-lactamase_39_67,TEM-1,beta-lactamase_39,P62593,1.01149,NO,67,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-2.231,-2.772,0.541,,0.006,G,P,0.55,-0.81,1.463,,65.03,HHP,-1.502,0.0495842,0.00409753,1.01149 E1_Ubiquitin_A46S,E1_Ubiquitin_46,Uba1,E1_Ubiquitin,P0CG63,1.01149,NO,46,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.367,-2.242,0.875,,0.398,T,L,,-0.8,,,,HHO,-1.17167,0.18783,0.004233,1.01149 E1_Ubiquitin_F45H,E1_Ubiquitin_45,Uba1,E1_Ubiquitin,P0CG63,1.01149,NO,45,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.149,-4.272,3.123,,0.26,E,B,,-0.99,,,,HHH,-1.316,0.18783,0.00193245,1.01149 E1_Ubiquitin_G47A,E1_Ubiquitin_47,Uba1,E1_Ubiquitin,P0CG63,1.01149,NO,47,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.999,-2.773,1.774,,0.057,T,l,,-1.21,,,,HOB,-1.195,0.18783,0.00142261,1.01149 E1_Ubiquitin_I44M,E1_Ubiquitin_44,Uba1,E1_Ubiquitin,P0CG63,1.01149,NO,44,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.432,-4.044,2.612,,,E,B,0.27,-1.17,4.57,,78.74,HHH,-1.25633,0.18783,0.00209731,1.01149 E1_Ubiquitin_L43L,E1_Ubiquitin_43,Uba1,E1_Ubiquitin,P0CG63,1.01149,NO,43,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.188,-1.188,,,,E,B,,-1.17,,,,BHH,-1.30733,0.18783,0.00190185,1.01149 E1_Ubiquitin_Q40G,E1_Ubiquitin_40,Uba1,E1_Ubiquitin,P0CG63,1.01149,NO,40,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-1.48,-3.271,1.791,,0.387,G,A,,0.03,,,,OPP,-1.365,0.18783,0.0037961,1.01149 E1_Ubiquitin_R74G,E1_Ubiquitin_74,Uba1,E1_Ubiquitin,P0CG63,1.01149,NO,74,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.302,-3.229,1.927,,0.838,T,A,,3.15,,,,HBO,-1.11333,0.18783,0.00180798,1.01149 E1_Ubiquitin_R74W,E1_Ubiquitin_74,Uba1,E1_Ubiquitin,P0CG63,1.01149,NO,74,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.302,-5.193,3.891,,0.838,T,A,,3.15,,,,HBO,-1.11333,0.18783,0.00180798,1.01149 gb1_E241K,gb1_241,gb1,gb1,P06654,1.01149,NO,241,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.672,-3.018,1.346,,,,,,,0.344,,11.83,OAP,-1.27933,0.177985,0.00250604,1.01149 beta-lactamase_625_K53L,beta-lactamase_625_53,TEM-1,beta-lactamase_625,P62593,1.0115,NO,53,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-2.313,-2.678,0.365,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.213352,0.00383383,1.0115 beta-lactamase_625_T131S,beta-lactamase_625_131,TEM-1,beta-lactamase_625,P62593,1.0115,NO,131,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.328,-1.912,0.584,,,H,A,0.22,-0.69,2.031,,67.48,PPH,-1.00867,0.213352,0.00345886,1.0115 beta-lactamase_A222S,beta-lactamase_222,TEM-1,beta-lactamase,P62593,1.01152,NO,222,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.103,-2.253,0.15,5.2262,0.233,H,A,0.47,-0.25,0.379,,77.62,PHH,-1.63733,0.221079,0.00466094,1.01152 beta-lactamase_0_R91Q,beta-lactamase_0_91,TEM-1,beta-lactamase_0,P62593,1.01153,NO,91,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.392,-2.363,0.971,,0.444,,B,1.2,0.96,4.557,,50.35,OBB,-1.73367,0.0500837,0.00380226,1.01153 beta-lactamase_156_I258A,beta-lactamase_156_258,TEM-1,beta-lactamase_156,P62593,1.01153,NO,258,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.111618,0.007931,1.01153 beta-lactamase_156_L223T,beta-lactamase_156_223,TEM-1,beta-lactamase_156,P62593,1.01153,NO,223,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.055,-2.595,1.54,,0.27,,B,0.55,0.09,1.511,,74.48,HHO,-1.35033,0.111618,0.00372793,1.01153 kka2_1:8_L7M,kka2_1:8_7,Kka2,kka2_1:8,P00552,1.01153,NO,7,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.926,-2.658,0.732,,,,,,,,,71.59,OHB,-2.12333,0.100394,0.00269456,1.01153 kka2_1:8_L7M,kka2_1:8_7,Kka2,kka2_1:8,P00552,1.01153,NO,7,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.926,-2.658,0.732,,,,,,,,,71.59,OHB,-2.12333,0.100394,0.00269456,1.01153 beta-lactamase_156_A148W,beta-lactamase_156_148,TEM-1,beta-lactamase_156,P62593,1.01154,NO,148,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.757,-5.497,3.74,,0.379,H,A,0.46,-0.55,3.551,,72.73,PHH,-1.40167,0.111618,0.00547053,1.01154 beta-lactamase_39_T126R,beta-lactamase_39_126,TEM-1,beta-lactamase_39,P62593,1.01155,NO,126,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.122,-3.84,2.718,,0.05,H,A,0.22,-0.05,0.586,,44.41,HPH,-1.60467,0.0495842,0.00244552,1.01155 beta-lactamase_156_G154C,beta-lactamase_156_154,TEM-1,beta-lactamase_156,P62593,1.01156,NO,154,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.823,-5.058,4.235,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.111618,0.00180205,1.01156 beta-lactamase_156_L223S,beta-lactamase_156_223,TEM-1,beta-lactamase_156,P62593,1.01156,NO,223,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.055,-3.587,2.532,,0.27,,B,0.55,0.09,1.511,,74.48,HHO,-1.35033,0.111618,0.00372793,1.01156 beta-lactamase_A276S,beta-lactamase_276,TEM-1,beta-lactamase,P62593,1.01156,NO,276,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.144,-2.276,1.132,5.1387,0.117,H,A,0.52,-0.84,1.283,,44.06,HHA,-1.47,0.221079,0.0191712,1.01156 beta-lactamase_156_L28K,beta-lactamase_156_28,TEM-1,beta-lactamase_156,P62593,1.01157,NO,28,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.579,-3.608,2.029,,0.277,H,A,0.55,-0.16,3.262,,93.01,PHH,-2.11333,0.111618,0.00359321,1.01157 beta-lactamase_156_P143M,beta-lactamase_156_143,TEM-1,beta-lactamase_156,P62593,1.01157,NO,143,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.967,-4.554,3.587,,0.075,H,A,0.52,-0.37,0.479,,66.78,OOB,-1.354,0.111618,0.00114551,1.01157 beta-lactamase_39_E102C,beta-lactamase_39_102,TEM-1,beta-lactamase_39,P62593,1.01157,NO,102,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.118,-5.064,2.946,,0.722,S,B,1.04,1.82,3.87,,73.08,HAH,-1.581,0.0495842,0.00486633,1.01157 beta-lactamase_39_N130A,beta-lactamase_39_130,TEM-1,beta-lactamase_39,P62593,1.01157,NO,130,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-0.798,-3.303,2.505,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.0495842,0.000683376,1.01157 beta-lactamase_625_Q86N,beta-lactamase_625_86,TEM-1,beta-lactamase_625,P62593,1.01157,NO,86,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.4,-3.754,1.354,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.213352,0.00450027,1.01157 PSD95pdz3_G344S,PSD95pdz3_344,PSD95pdz3,PSD95pdz3,P31016,1.01157,NO,344,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.008,-2.842,1.834,4.83855,,,,,14.06,,,,HOO,-1.10767,0.0758425,0.00078498,1.01157 beta-lactamase_2500_S283K,beta-lactamase_2500_283,TEM-1,beta-lactamase_2500,P62593,1.01158,NO,283,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.361275,0.0429138,1.01158 beta-lactamase_625_C75I,beta-lactamase_625_75,TEM-1,beta-lactamase_625,P62593,1.01158,NO,75,C,I,CI,Special,Hydrophobic,5.07,6.02,0.95,198,121,131,10,108.5,166.7,58.2,-1.245,-3.708,2.463,,,H,A,0.46,-0.87,2.141,,50,HOO,-1.24333,0.213352,0.0034616,1.01158 Pab1_H134D,Pab1_134,Pab1,Pab1,P04147,1.01159,NO,134,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-1.542,-1.924,0.382,,,,,,,,,,HBO,-1.346,0.175299,0.00116356,1.01159 beta-lactamase_39_A183S,beta-lactamase_39_183,TEM-1,beta-lactamase_39,P62593,1.0116,NO,183,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.231,-2.011,0.78,,0.155,H,A,0.46,-0.91,1.237,,77.62,HHH,-1.53367,0.0495842,0.00296631,1.0116 beta-lactamase_A225E,beta-lactamase_225,TEM-1,beta-lactamase,P62593,1.0116,NO,225,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.845,-2.246,0.401,6.5181,1,T,B,0.58,-0.38,4.077,,74.48,OHO,-1.39967,0.221079,0.00465057,1.0116 beta-lactamase_39_L197E,beta-lactamase_39_197,TEM-1,beta-lactamase_39,P62593,1.01161,NO,197,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.853,-3.853,3,,0.007,S,B,0.55,0.33,1.559,,60.14,HHP,-1.833,0.0495842,0.00144602,1.01161 beta-lactamase_625_K53G,beta-lactamase_625_53,TEM-1,beta-lactamase_625,P62593,1.01161,NO,53,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-2.313,-2.824,0.511,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.213352,0.00383383,1.01161 beta-lactamase_625_L74V,beta-lactamase_625_74,TEM-1,beta-lactamase_625,P62593,1.01161,NO,74,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.296,-2.972,1.676,,,H,A,0.55,-0.91,0.895,,50,HHO,-1.34933,0.213352,0.00493255,1.01161 kka2_1:2_A87T,kka2_1:2_87,Kka2,kka2_1:2,P00552,1.01161,NO,87,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.917,-3.035,1.118,,1.039,S,L,0.46,1.57,22.675,22.675,65.53,AHO,-1.822,0.295029,0.00791281,1.01161 beta-lactamase_0_D271V,beta-lactamase_0_271,TEM-1,beta-lactamase_0,P62593,1.01164,NO,271,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.0500837,0.00752082,1.01164 beta-lactamase_156_E272I,beta-lactamase_156_272,TEM-1,beta-lactamase_156,P62593,1.01164,NO,272,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.111618,0.00545371,1.01164 gb1_A249P,gb1_249,gb1,gb1,P06654,1.01164,NO,249,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.739,-2.161,0.422,,,,,,,0.252,,44.87,AHH,-1.67367,0.177985,0.00333585,1.01164 gb1_I232T,gb1_232,gb1,gb1,P06654,1.01164,NO,232,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-2.175,-2.152,-0.023,,,,,,,0.766,,44.87,HHH,-2.152,0.177985,0.00580459,1.01164 beta-lactamase_39_I244F,beta-lactamase_39_244,TEM-1,beta-lactamase_39,P62593,1.01165,NO,244,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.555,-3.842,2.287,,,E,B,0.48,-0.84,1.325,,77.62,OHH,-1.385,0.0495842,0.00605379,1.01165 beta-lactamase_39_L49T,beta-lactamase_39_49,TEM-1,beta-lactamase_39,P62593,1.01165,NO,49,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.897,-1.853,-0.044,,0.131,T,A,0.55,0.04,13.838,13.838,64.69,AHP,-1.99233,0.0495842,0.00401477,1.01165 beta-lactamase_39_Y44F,beta-lactamase_39_44,TEM-1,beta-lactamase_39,P62593,1.01165,NO,44,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-2.547,-2.714,0.167,,,E,B,0.21,-0.45,2.683,,73.78,OHH,-1.86267,0.0495842,0.00426364,1.01165 beta-lactamase_R189K,beta-lactamase_189,TEM-1,beta-lactamase,P62593,1.01165,NO,189,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.844,-2.391,0.547,5.74877,0.278,H,A,0.68,1.01,1.512,,72.73,HBB,-1.668,0.221079,0.0050699,1.01165 beta-lactamase_39_A34F,beta-lactamase_39_34,TEM-1,beta-lactamase_39,P62593,1.01166,NO,34,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.059,-3.937,1.878,,,H,A,0.46,-0.54,13.292,13.292,73.78,AHA,-1.74967,0.0495842,0.00407913,1.01166 beta-lactamase_39_E166K,beta-lactamase_39_166,TEM-1,beta-lactamase_39,P62593,1.01167,NO,166,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.756,-2.625,0.869,,0.508,G,A,1.04,1.05,17.227,17.227,73.08,OAH,-1.42233,0.0495842,0.00512989,1.01167 beta-lactamase_39_L79A,beta-lactamase_39_79,TEM-1,beta-lactamase_39,P62593,1.01167,NO,79,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.842,-3.103,2.261,,0.007,H,A,0.55,-0.16,0.823,,50.35,HHP,-1.44333,0.0495842,0.000947397,1.01167 beta-lactamase_39_S122R,beta-lactamase_39_122,TEM-1,beta-lactamase_39,P62593,1.01167,NO,122,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.406,-3.131,0.725,,0.352,H,A,0.27,-0.54,2.004,,77.62,OPH,-1.39767,0.0495842,0.00497825,1.01167 kka2_1:2_D156H,kka2_1:2_156,Kka2,kka2_1:2,P00552,1.01167,NO,156,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.696,-4.723,3.027,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.295029,0.00926998,1.01167 beta-lactamase_2500_L223I,beta-lactamase_2500_223,TEM-1,beta-lactamase_2500,P62593,1.01168,NO,223,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.055,-2.996,1.941,,0.27,,B,0.55,0.09,1.334,,74.48,HHO,-1.35033,0.361275,0.00372793,1.01168 beta-lactamase_2500_T263M,beta-lactamase_2500_263,TEM-1,beta-lactamase_2500,P62593,1.01168,NO,263,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.361275,0.0110582,1.01168 beta-lactamase_625_P60L,beta-lactamase_625_60,TEM-1,beta-lactamase_625,P62593,1.01168,NO,60,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-2.469,-2.818,0.349,,0.256,T,A,0.52,-0.56,3.653,,77.62,BOA,-1.97633,0.213352,0.00521318,1.01168 beta-lactamase_625_R159V,beta-lactamase_625_159,TEM-1,beta-lactamase_625,P62593,1.01168,NO,159,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-0.94,-3.779,2.839,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.213352,0.00108472,1.01168 PSD95pdz3_A370L,PSD95pdz3_370,PSD95pdz3,PSD95pdz3,P31016,1.01168,NO,370,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.307,-2.815,1.508,5.22304,,,,,17.284,,,,PHP,-1.57967,0.0758425,0.000429106,1.01168 beta-lactamase_156_R220H,beta-lactamase_156_220,TEM-1,beta-lactamase_156,P62593,1.01169,NO,220,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-0.942,-4.298,3.356,,0.295,I,A,1.2,-0.76,2.164,,74.48,HBP,-1.33633,0.111618,0.00232421,1.01169 beta-lactamase_625_G243S,beta-lactamase_625_243,TEM-1,beta-lactamase_625,P62593,1.01169,NO,243,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.213352,0.00464034,1.01169 beta-lactamase_625_T138D,beta-lactamase_625_138,TEM-1,beta-lactamase_625,P62593,1.01169,NO,138,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.506,-2.325,-0.181,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.213352,0.00487868,1.01169 beta-lactamase_2500_L38M,beta-lactamase_2500_38,TEM-1,beta-lactamase_2500,P62593,1.0117,NO,38,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.343,-4.186,2.843,,0.088,H,A,0.55,0.2,2.71,,64.34,PHO,-1.78033,0.361275,0.00373244,1.0117 beta-lactamase_39_S51L,beta-lactamase_39_51,TEM-1,beta-lactamase_39,P62593,1.0117,NO,51,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.526,-3.495,1.969,,0.496,T,A,0.27,0.26,2.964,,72.73,PPO,-1.88467,0.0495842,0.00504821,1.0117 PSD95pdz3_A343W,PSD95pdz3_343,PSD95pdz3,PSD95pdz3,P31016,1.0117,NO,343,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.307,-5.004,3.697,5.585,,,,,14.728,,,,HHO,-1.22067,0.0758425,0.000798084,1.0117 beta-lactamase_156_A84D,beta-lactamase_156_84,TEM-1,beta-lactamase_156,P62593,1.01171,NO,84,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.651,-2.92,1.269,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.111618,0.00503822,1.01171 beta-lactamase_156_L55R,beta-lactamase_156_55,TEM-1,beta-lactamase_156,P62593,1.01171,NO,55,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.86,-3.1,1.24,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.111618,0.00403741,1.01171 beta-lactamase_I3P,beta-lactamase_3,TEM-1,beta-lactamase,P62593,1.01171,NO,3,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-2.143,-3.857,1.714,,,,,,,3.946,,93.01,PHP,-2.21633,0.221079,0.00349304,1.01171 beta-lactamase_156_R91D,beta-lactamase_156_91,TEM-1,beta-lactamase_156,P62593,1.01172,NO,91,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.392,-3.521,2.129,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.111618,0.00380226,1.01172 kka2_1:4_P249T,kka2_1:4_249,Kka2,kka2_1:4,P00552,1.01172,NO,249,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.867,-2.639,0.772,,0.406,.,B,0.52,-0.01,,,92.05,HOA,-1.66867,0.168804,0.011045,1.01172 beta-lactamase_156_D174H,beta-lactamase_156_174,TEM-1,beta-lactamase_156,P62593,1.01173,NO,174,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.738,-4.455,3.717,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.111618,0.00125633,1.01173 beta-lactamase_156_T116H,beta-lactamase_156_116,TEM-1,beta-lactamase_156,P62593,1.01173,NO,116,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.28,-4.615,3.335,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.111618,0.00336175,1.01173 beta-lactamase_39_Q204V,beta-lactamase_39_204,TEM-1,beta-lactamase_39,P62593,1.01173,NO,204,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-1.382,-3.595,2.213,,0.204,H,A,0.64,0.09,0.489,,66.08,PPH,-1.49067,0.0495842,0.00364106,1.01173 beta-lactamase_39_G52R,beta-lactamase_39_52,TEM-1,beta-lactamase_39,P62593,1.01174,NO,52,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.149,-3.956,2.807,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.0495842,0.00340138,1.01174 beta-lactamase_156_L49I,beta-lactamase_156_49,TEM-1,beta-lactamase_156,P62593,1.01175,NO,49,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.897,-3.523,1.626,,0.131,T,A,0.55,0.04,3.112,,64.69,AHP,-1.99233,0.111618,0.00401477,1.01175 beta-lactamase_156_D36R,beta-lactamase_156_36,TEM-1,beta-lactamase_156,P62593,1.01176,NO,36,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.732,-2.847,0.115,,0.555,H,A,0.75,1.17,14.871,14.871,77.62,AAP,-1.91167,0.111618,0.00476483,1.01176 beta-lactamase_39_G216K,beta-lactamase_39_216,TEM-1,beta-lactamase_39,P62593,1.01178,NO,216,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.477,-2.765,1.288,,0.437,I,A,0.29,-0.58,0.834,,74.48,HOO,-1.68067,0.0495842,0.00639568,1.01178 beta-lactamase_39_H151A,beta-lactamase_39_151,TEM-1,beta-lactamase_39,P62593,1.01178,NO,151,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-2.96,-3.11,0.15,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.0495842,0.00216946,1.01178 beta-lactamase_39_P224M,beta-lactamase_39_224,TEM-1,beta-lactamase_39,P62593,1.01179,NO,224,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.893,-4.704,3.811,,0.383,,B,0.52,-0.3,3.169,,74.48,HOH,-1.26433,0.0495842,0.00189564,1.01179 beta-lactamase_39_T178Q,beta-lactamase_39_178,TEM-1,beta-lactamase_39,P62593,1.01179,NO,178,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-0.791,-3.899,3.108,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.0495842,0.000684366,1.01179 beta-lactamase_625_V106K,beta-lactamase_625_106,TEM-1,beta-lactamase_625,P62593,1.01179,NO,106,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.218,-3.831,2.613,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.213352,0.00304168,1.01179 gb1_T275D,gb1_275,gb1,gb1,P06654,1.01179,NO,275,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.727,-2.239,0.512,,,,,,,0.511,,35.71,HPB,-1.637,0.177985,0.00606618,1.01179 beta-lactamase_39_S201P,beta-lactamase_39_201,TEM-1,beta-lactamase_39,P62593,1.0118,NO,201,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.183,-3.79,2.607,,0.064,H,A,0.27,-0.07,3.54,,64.69,HPB,-1.451,0.0495842,0.00198815,1.0118 beta-lactamase_39_S221A,beta-lactamase_39_221,TEM-1,beta-lactamase_39,P62593,1.0118,NO,221,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.754,-1.332,-0.422,,0.624,H,A,0.27,-0.2,2.69,,74.48,BPH,-1.59967,0.0495842,0.0046094,1.0118 beta-lactamase_625_E119S,beta-lactamase_625_119,TEM-1,beta-lactamase_625,P62593,1.0118,NO,119,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.412,-2.681,1.269,,0.358,H,A,1.04,0.51,1.034,,63.99,BAH,-1.623,0.213352,0.00386966,1.0118 beta-lactamase_625_I54L,beta-lactamase_625_54,TEM-1,beta-lactamase_625,P62593,1.0118,NO,54,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-2.838,-2.471,-0.367,,0.669,E,B,0.48,-0.14,3.946,,73.78,BHH,-2.337,0.213352,0.00403589,1.0118 beta-lactamase_156_E279G,beta-lactamase_156_279,TEM-1,beta-lactamase_156,P62593,1.01181,NO,279,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.038,-3.588,2.55,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.111618,0.0192826,1.01181 beta-lactamase_156_P105W,beta-lactamase_156_105,TEM-1,beta-lactamase_156,P62593,1.01181,NO,105,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.813,-5.545,4.732,,0.226,T,A,0.52,0.8,1.154,,63.29,POH,-1.01533,0.111618,0.0011981,1.01181 beta-lactamase_156_P255Q,beta-lactamase_156_255,TEM-1,beta-lactamase_156,P62593,1.01181,NO,255,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.111618,0.00499612,1.01181 beta-lactamase_156_R242C,beta-lactamase_156_242,TEM-1,beta-lactamase_156,P62593,1.01181,NO,242,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.111618,0.00452879,1.01181 beta-lactamase_625_E145K,beta-lactamase_625_145,TEM-1,beta-lactamase_625,P62593,1.01181,NO,145,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.357,-3.472,1.115,,0.545,H,A,1.04,0.79,2.64,,77.62,BAH,-2.069,0.213352,0.00553285,1.01181 beta-lactamase_0_A222T,beta-lactamase_0_222,TEM-1,beta-lactamase_0,P62593,1.01182,NO,222,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.103,-2.805,0.702,,0.233,H,A,0.46,-0.25,2.015,,77.62,PHH,-1.63733,0.0500837,0.00466094,1.01182 beta-lactamase_2500_A182Y,beta-lactamase_2500_182,TEM-1,beta-lactamase_2500,P62593,1.01182,NO,182,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.777,-4.299,2.522,,0.136,H,A,0.46,-0.66,2.032,,93.01,OHH,-1.27367,0.361275,0.00559099,1.01182 beta-lactamase_39_A124T,beta-lactamase_39_124,TEM-1,beta-lactamase_39,P62593,1.01182,NO,124,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.181,-1.586,0.405,,,H,A,0.46,-0.9,1.367,,64.34,HHH,-1.152,0.0495842,0.00481399,1.01182 beta-lactamase_39_T69I,beta-lactamase_39_69,TEM-1,beta-lactamase_39,P62593,1.01182,NO,69,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-0.973,-3.64,2.667,,,G,A,0.22,-1.24,4.194,,93.01,PPH,-1.01833,0.0495842,0.00127498,1.01182 beta-lactamase_2500_R239H,beta-lactamase_2500_239,TEM-1,beta-lactamase_2500,P62593,1.01183,NO,239,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.361275,0.00213852,1.01183 beta-lactamase_39_M127T,beta-lactamase_39_127,TEM-1,beta-lactamase_39,P62593,1.01183,NO,127,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-2.251,-2.593,0.342,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.0495842,0.00437927,1.01183 kka2_1:8_E142D,kka2_1:8_142,Kka2,kka2_1:8,P00552,1.01183,NO,142,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.221,-3.049,0.828,,0.471,H,A,1.04,0.85,2.655,,65.53,HAB,-2.08033,0.100394,0.00748883,1.01183 kka2_1:8_E142D,kka2_1:8_142,Kka2,kka2_1:8,P00552,1.01183,NO,142,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.221,-3.049,0.828,,0.471,H,A,1.04,0.85,2.655,,65.53,HAB,-2.08033,0.100394,0.00748883,1.01183 beta-lactamase_156_F70A,beta-lactamase_156_70,TEM-1,beta-lactamase_156,P62593,1.01184,NO,70,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.169,-3.227,2.058,,,H,A,0.58,-1.34,1.918,,63.99,PHB,-0.980667,0.111618,0.00193499,1.01184 beta-lactamase_2500_S80Y,beta-lactamase_2500_80,TEM-1,beta-lactamase_2500,P62593,1.01184,NO,80,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.029,-4.297,2.268,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.361275,0.00565569,1.01184 PSD95pdz3_T385M,PSD95pdz3_385,PSD95pdz3,PSD95pdz3,P31016,1.01184,NO,385,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.533,-4.257,2.724,5.57157,,,,,23.6871,4.527,,87.71,PPH,-1.56567,0.0758425,0.000545119,1.01184 beta-lactamase_156_K53M,beta-lactamase_156_53,TEM-1,beta-lactamase_156,P62593,1.01185,NO,53,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-2.313,-4.641,2.328,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.111618,0.00383383,1.01185 beta-lactamase_39_R159W,beta-lactamase_39_159,TEM-1,beta-lactamase_39,P62593,1.01185,NO,159,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-0.94,-5.32,4.38,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.0495842,0.00108472,1.01185 beta-lactamase_625_E108H,beta-lactamase_625_108,TEM-1,beta-lactamase_625,P62593,1.01185,NO,108,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.46,-4.53,3.07,,0.572,G,A,1.04,1.87,20.151,20.151,72.73,PAB,-1.437,0.213352,0.00413372,1.01185 kka2_1:4_V49T,kka2_1:4_49,Kka2,kka2_1:4,P00552,1.01186,NO,49,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.614,-3.462,1.848,,,E,B,0.44,-0.77,1.233,,64.39,HHB,-1.3,0.168804,0.00615685,1.01186 beta-lactamase_39_A148P,beta-lactamase_39_148,TEM-1,beta-lactamase_39,P62593,1.01187,NO,148,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.757,-3.925,2.168,,0.379,H,A,0.46,-0.55,3.551,,72.73,PHH,-1.40167,0.0495842,0.00547053,1.01187 beta-lactamase_39_R275K,beta-lactamase_39_275,TEM-1,beta-lactamase_39,P62593,1.01187,NO,275,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.0495842,0.0141984,1.01187 beta-lactamase_156_S201Y,beta-lactamase_156_201,TEM-1,beta-lactamase_156,P62593,1.01188,NO,201,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.183,-4.222,3.039,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.111618,0.00198815,1.01188 beta-lactamase_2500_V29G,beta-lactamase_2500_29,TEM-1,beta-lactamase_2500,P62593,1.01188,NO,29,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-2.856,-2.66,-0.196,,0.733,H,A,0.44,-0.78,1.931,,93.01,HHB,-2.24733,0.361275,0.00318969,1.01188 beta-lactamase_39_F64Q,beta-lactamase_39_64,TEM-1,beta-lactamase_39,P62593,1.01189,NO,64,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-0.841,-4.349,3.508,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.0495842,0.000947691,1.01189 beta-lactamase_625_T263V,beta-lactamase_625_263,TEM-1,beta-lactamase_625,P62593,1.01189,NO,263,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.213352,0.0110582,1.01189 beta-lactamase_156_A34Q,beta-lactamase_156_34,TEM-1,beta-lactamase_156,P62593,1.01191,NO,34,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.059,-4.16,2.101,,,H,A,0.46,-0.54,3.614,,73.78,AHA,-1.74967,0.111618,0.00407913,1.01191 beta-lactamase_625_E169A,beta-lactamase_625_169,TEM-1,beta-lactamase_625,P62593,1.01193,NO,169,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.23,-2.486,1.256,,0.337,,A,1.04,1,1.806,,73.08,PAH,-1.16533,0.213352,0.00400994,1.01193 beta-lactamase_625_R118K,beta-lactamase_625_118,TEM-1,beta-lactamase_625,P62593,1.01193,NO,118,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.413,-3.492,1.079,,0.457,H,A,1.2,1.39,2.144,,77.62,HBA,-1.785,0.213352,0.00538794,1.01193 beta-lactamase_39_E145Y,beta-lactamase_39_145,TEM-1,beta-lactamase_39,P62593,1.01194,NO,145,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.357,-4.381,2.024,,0.545,H,A,1.04,0.79,1.199,,77.62,BAH,-2.069,0.0495842,0.00553285,1.01194 beta-lactamase_39_I54F,beta-lactamase_39_54,TEM-1,beta-lactamase_39,P62593,1.01194,NO,54,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-2.838,-4.242,1.404,,0.669,E,B,0.48,-0.14,1.349,,73.78,BHH,-2.337,0.0495842,0.00403589,1.01194 beta-lactamase_39_K30S,beta-lactamase_39_30,TEM-1,beta-lactamase_39,P62593,1.01194,NO,30,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-2.307,-3.277,0.97,,0.142,H,A,2.34,-0.65,6.717,,93.01,HBH,-2.32833,0.0495842,0.00448593,1.01194 beta-lactamase_625_Q37M,beta-lactamase_625_37,TEM-1,beta-lactamase_625,P62593,1.01194,NO,37,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.134,-4.645,2.511,,0.613,H,A,0.64,1.98,1.318,,73.08,APH,-2.06967,0.213352,0.00425833,1.01194 gb1_V247H,gb1_247,gb1,gb1,P06654,1.01194,NO,247,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.711,-4.68,2.969,,,,,,,0.805,,44.87,HHA,-1.485,0.177985,0.00435373,1.01194 beta-lactamase_156_A132G,beta-lactamase_156_132,TEM-1,beta-lactamase_156,P62593,1.01195,NO,132,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.9,-3.009,2.109,,,H,A,0.46,-0.93,10.621,,64.69,PHH,-1.138,0.111618,0.000962524,1.01195 beta-lactamase_156_L223Q,beta-lactamase_156_223,TEM-1,beta-lactamase_156,P62593,1.01197,NO,223,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.055,-4.184,3.129,,0.27,,B,0.55,0.09,1.511,,74.48,HHO,-1.35033,0.111618,0.00372793,1.01197 beta-lactamase_156_M180E,beta-lactamase_156_180,TEM-1,beta-lactamase_156,P62593,1.01198,NO,180,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-2.795,-3.532,0.737,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.111618,0.00552048,1.01198 kka2_1:8_V83G,kka2_1:8_83,Kka2,kka2_1:8,P00552,1.01198,NO,83,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-2.567,-3.646,1.079,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.100394,0.00650486,1.01198 kka2_1:8_V83G,kka2_1:8_83,Kka2,kka2_1:8,P00552,1.01198,NO,83,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-2.567,-3.646,1.079,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.100394,0.00650486,1.01198 beta-lactamase_156_K213F,beta-lactamase_156_213,TEM-1,beta-lactamase_156,P62593,1.01199,NO,213,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.81,-4.437,2.627,,0.67,,A,2.34,0.29,3.924,,67.83,ABH,-1.57767,0.111618,0.00610411,1.01199 beta-lactamase_2500_T112A,beta-lactamase_2500_112,TEM-1,beta-lactamase_2500,P62593,1.01199,NO,112,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.186,-1.933,-0.253,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.361275,0.00531334,1.01199 beta-lactamase_39_P60D,beta-lactamase_39_60,TEM-1,beta-lactamase_39,P62593,1.01199,NO,60,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-2.469,-3.676,1.207,,0.256,T,A,0.52,-0.56,21.37,21.37,77.62,BOA,-1.97633,0.0495842,0.00521318,1.01199 beta-lactamase_39_T116N,beta-lactamase_39_116,TEM-1,beta-lactamase_39,P62593,1.01199,NO,116,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.28,-2.515,1.235,,0.115,E,B,0.22,-0.12,1.133,,67.48,HPH,-1.39967,0.0495842,0.00336175,1.01199 beta-lactamase_625_A34M,beta-lactamase_625_34,TEM-1,beta-lactamase_625,P62593,1.01199,NO,34,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.059,-4.351,2.292,,,H,A,0.46,-0.54,3.614,,73.78,AHA,-1.74967,0.213352,0.00407913,1.01199 beta-lactamase_156_A40Y,beta-lactamase_156_40,TEM-1,beta-lactamase_156,P62593,1.012,NO,40,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.402,-4.322,2.92,,0.155,S,B,0.46,0.21,1.357,,73.78,OHB,-1.40267,0.111618,0.00490026,1.012 beta-lactamase_156_A230L,beta-lactamase_156_230,TEM-1,beta-lactamase_156,P62593,1.01201,NO,230,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.154,-3.416,2.262,,0.01,E,B,0.46,-1.17,2.179,,50,HHA,-1.079,0.111618,0.00516841,1.01201 beta-lactamase_156_E169M,beta-lactamase_156_169,TEM-1,beta-lactamase_156,P62593,1.01201,NO,169,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.23,-4.676,3.446,,0.337,,A,1.04,1,3.516,,73.08,PAH,-1.16533,0.111618,0.00400994,1.01201 beta-lactamase_156_I206C,beta-lactamase_156_206,TEM-1,beta-lactamase_156,P62593,1.01201,NO,206,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-2.429,-4.969,2.54,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.111618,0.00528934,1.01201 beta-lactamase_2500_D252Q,beta-lactamase_2500_252,TEM-1,beta-lactamase_2500,P62593,1.01201,NO,252,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.94,,,,0.766,,B,1.59,1.16,,,67.83,OAO,-2.0965,0.361275,0.00575769,1.01201 beta-lactamase_39_T112P,beta-lactamase_39_112,TEM-1,beta-lactamase_39,P62593,1.01201,NO,112,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.186,-3.939,1.753,,0.921,T,A,0.22,1.06,2.87,,73.78,HPA,-1.925,0.0495842,0.00531334,1.01201 beta-lactamase_156_D99Y,beta-lactamase_156_99,TEM-1,beta-lactamase_156,P62593,1.01202,NO,99,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.191,-4.234,3.043,,0.402,G,A,0.75,0.36,3.529,,64.69,PAH,-1.794,0.111618,0.00305446,1.01202 beta-lactamase_2500_R118N,beta-lactamase_2500_118,TEM-1,beta-lactamase_2500,P62593,1.01202,NO,118,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.413,-3.711,1.298,,0.457,H,A,1.2,1.39,2.144,,77.62,HBA,-1.785,0.361275,0.00538794,1.01202 beta-lactamase_39_M127G,beta-lactamase_39_127,TEM-1,beta-lactamase_39,P62593,1.01203,NO,127,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-2.251,-3.785,1.534,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.0495842,0.00437927,1.01203 beta-lactamase_625_E238H,beta-lactamase_625_238,TEM-1,beta-lactamase_625,P62593,1.01203,NO,238,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.213352,0.00743256,1.01203 beta-lactamase_K144R,beta-lactamase_144,TEM-1,beta-lactamase,P62593,1.01203,NO,144,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-2.388,-3.055,0.667,6.02507,0.863,H,A,2.81,1.27,0.515,,77.62,OBA,-1.904,0.221079,0.00481141,1.01203 kka2_1:8_D127A,kka2_1:8_127,Kka2,kka2_1:8,P00552,1.01203,NO,127,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.364,-2.492,1.128,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.100394,0.00660501,1.01203 kka2_1:8_D127A,kka2_1:8_127,Kka2,kka2_1:8,P00552,1.01203,NO,127,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.364,-2.492,1.128,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.100394,0.00660501,1.01203 beta-lactamase_A225H,beta-lactamase_225,TEM-1,beta-lactamase,P62593,1.01205,NO,225,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.845,-3.109,1.264,6.5181,1,T,B,0.58,-0.38,4.077,,74.48,OHO,-1.39967,0.221079,0.00465057,1.01205 beta-lactamase_F22C,beta-lactamase_22,TEM-1,beta-lactamase,P62593,1.01205,NO,22,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-2.676,-4.977,2.301,,,,,,,1.616,,73.08,HHH,-2.03233,0.221079,0.00262842,1.01205 beta-lactamase_F58W,beta-lactamase_58,TEM-1,beta-lactamase,P62593,1.01205,NO,58,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-2.914,-2.275,-0.639,5.55634,0.266,E,B,1.33,-0.07,2.467,,77.62,PHB,-2.059,0.221079,0.00523369,1.01205 beta-lactamase_L73I,beta-lactamase_73,TEM-1,beta-lactamase,P62593,1.01205,NO,73,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.507,-2.52,1.013,5.84139,,H,A,1.75,-0.64,2.09,,67.83,HHH,-1.487,0.221079,0.00488983,1.01205 beta-lactamase_Q265E,beta-lactamase_265,TEM-1,beta-lactamase,P62593,1.01205,NO,265,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.58,-2.392,-0.188,6.62674,1.116,,A,0.03,1.17,12.514,12.514,69.58,PPH,-1.978,0.221079,0.00811926,1.01205 beta-lactamase_0_D155Y,beta-lactamase_0_155,TEM-1,beta-lactamase_0,P62593,1.01206,NO,155,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-0.889,-4.387,3.498,,0.049,,B,0.75,-0.9,16.833,16.833,64.69,OAB,-1.62267,0.0500837,0.00135315,1.01206 beta-lactamase_156_R59Y,beta-lactamase_156_59,TEM-1,beta-lactamase_156,P62593,1.01206,NO,59,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.345,-4.267,2.922,,0.329,S,L,1.2,-0.09,2.995,,73.08,HBO,-2.24267,0.111618,0.00318082,1.01206 beta-lactamase_156_E26D,beta-lactamase_156_26,TEM-1,beta-lactamase_156,P62593,1.01207,NO,26,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.454,-2.507,0.053,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.111618,0.00297948,1.01207 beta-lactamase_625_M67H,beta-lactamase_625_67,TEM-1,beta-lactamase_625,P62593,1.01207,NO,67,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-2.231,-4.763,2.532,,0.006,G,P,0.55,-0.81,2.653,,65.03,HHP,-1.502,0.213352,0.00409753,1.01207 beta-lactamase_625_G281C,beta-lactamase_625_281,TEM-1,beta-lactamase_625,P62593,1.01208,NO,281,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.213352,0.0406482,1.01208 beta-lactamase_156_K30Q,beta-lactamase_156_30,TEM-1,beta-lactamase_156,P62593,1.01209,NO,30,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-2.307,-2.158,-0.149,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.111618,0.00448593,1.01209 beta-lactamase_625_V259T,beta-lactamase_625_259,TEM-1,beta-lactamase_625,P62593,1.0121,NO,259,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.213352,0.0070773,1.0121 beta-lactamase_156_K190V,beta-lactamase_156_190,TEM-1,beta-lactamase_156,P62593,1.01211,NO,190,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.994,-2.992,0.998,,0.371,H,A,2.34,0.16,1.513,,77.62,BBH,-1.64167,0.111618,0.00574527,1.01211 beta-lactamase_625_L74I,beta-lactamase_625_74,TEM-1,beta-lactamase_625,P62593,1.01211,NO,74,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.296,-2.577,1.281,,,H,A,0.55,-0.91,0.895,,50,HHO,-1.34933,0.213352,0.00493255,1.01211 beta-lactamase_625_T126D,beta-lactamase_625_126,TEM-1,beta-lactamase_625,P62593,1.01211,NO,126,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.122,-2.344,1.222,,0.05,H,A,0.22,-0.05,0.817,,44.41,HPH,-1.60467,0.213352,0.00244552,1.01211 beta-lactamase_156_R275A,beta-lactamase_156_275,TEM-1,beta-lactamase_156,P62593,1.01212,NO,275,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.111618,0.0141984,1.01212 beta-lactamase_156_T112R,beta-lactamase_156_112,TEM-1,beta-lactamase_156,P62593,1.01212,NO,112,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.186,-3.88,1.694,,0.921,T,A,0.22,1.06,2.87,,73.78,HPA,-1.925,0.111618,0.00531334,1.01212 beta-lactamase_2500_T193R,beta-lactamase_2500_193,TEM-1,beta-lactamase_2500,P62593,1.01212,NO,193,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.914,-4.014,2.1,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.361275,0.00482669,1.01212 beta-lactamase_625_L28V,beta-lactamase_625_28,TEM-1,beta-lactamase_625,P62593,1.01212,NO,28,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.579,-1.979,0.4,,0.277,H,A,0.55,-0.16,2.716,,93.01,PHH,-2.11333,0.213352,0.00359321,1.01212 beta-lactamase_R176R,beta-lactamase_176,TEM-1,beta-lactamase,P62593,1.01212,NO,176,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-0.863,-0.863,,5.61264,0.385,T,B,0.68,-0.63,,,,ABA,-1.38867,0.221079,0.00105554,1.01212 beta-lactamase_156_H156M,beta-lactamase_156_156,TEM-1,beta-lactamase_156,P62593,1.01213,NO,156,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-3.156,-3.543,0.387,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.111618,0.00468596,1.01213 beta-lactamase_156_L284C,beta-lactamase_156_284,TEM-1,beta-lactamase_156,P62593,1.01213,NO,284,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.111618,0.0686156,1.01213 beta-lactamase_39_G243M,beta-lactamase_39_243,TEM-1,beta-lactamase_39,P62593,1.01214,NO,243,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.0495842,0.00464034,1.01214 kka2_1:2_I141M,kka2_1:2_141,Kka2,kka2_1:2,P00552,1.01214,NO,141,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.495,-2.864,1.369,,0.068,H,A,0.48,-0.01,0.819,,92.05,BHA,-1.689,0.295029,0.00744745,1.01214 beta-lactamase_156_G240H,beta-lactamase_156_240,TEM-1,beta-lactamase_156,P62593,1.01216,NO,240,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.111618,0.00591201,1.01216 beta-lactamase_156_S57A,beta-lactamase_156_57,TEM-1,beta-lactamase_156,P62593,1.01216,NO,57,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.918,-1.894,-0.024,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.111618,0.00492804,1.01216 beta-lactamase_39_P250R,beta-lactamase_39_250,TEM-1,beta-lactamase_39,P62593,1.01216,NO,250,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.0495842,0.00550899,1.01216 kka2_1:1_D5Q,kka2_1:1_5,Kka2,kka2_1:1,P00552,1.01216,NO,5,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.306,-3.312,2.006,,,,,,,0.895,,71.59,PAO,-1.784,0.520039,0.00222864,1.01216 beta-lactamase_156_E238R,beta-lactamase_156_238,TEM-1,beta-lactamase_156,P62593,1.01218,NO,238,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.002,-3.465,1.463,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.111618,0.00743256,1.01218 beta-lactamase_2500_K109M,beta-lactamase_2500_109,TEM-1,beta-lactamase_2500,P62593,1.01218,NO,109,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.734,-4.742,3.008,,0.787,G,A,2.34,2.21,0.998,,72.73,ABB,-1.63333,0.361275,0.00462493,1.01218 beta-lactamase_625_K109Y,beta-lactamase_625_109,TEM-1,beta-lactamase_625,P62593,1.01218,NO,109,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.734,-4.334,2.6,,0.787,G,A,2.34,2.21,7.243,,72.73,ABB,-1.63333,0.213352,0.00462493,1.01218 beta-lactamase_D99E,beta-lactamase_99,TEM-1,beta-lactamase,P62593,1.01218,NO,99,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.191,-2.122,0.931,5.66081,0.402,G,A,0.23,0.36,1.318,,64.69,PAH,-1.794,0.221079,0.00305446,1.01218 beta-lactamase_S80K,beta-lactamase_80,TEM-1,beta-lactamase,P62593,1.01218,NO,80,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.029,-2.901,0.872,5.23748,0.192,H,A,0.25,0.46,2.256,,77.62,HPB,-1.44567,0.221079,0.00565569,1.01218 beta-lactamase_156_E46A,beta-lactamase_156_46,TEM-1,beta-lactamase_156,P62593,1.01219,NO,46,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.94,-2.586,0.646,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.111618,0.00427568,1.01219 beta-lactamase_2500_G90E,beta-lactamase_2500_90,TEM-1,beta-lactamase_2500,P62593,1.01219,NO,90,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-2.091,-2.175,0.084,,0.598,T,A,0.29,0.32,1.2,,77.62,HOB,-1.52633,0.361275,0.00490273,1.01219 beta-lactamase_156_I258L,beta-lactamase_156_258,TEM-1,beta-lactamase_156,P62593,1.0122,NO,258,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.111618,0.007931,1.0122 beta-lactamase_K213Q,beta-lactamase_213,TEM-1,beta-lactamase,P62593,1.0122,NO,213,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.81,-2.028,0.218,5.63167,0.67,,A,1.59,0.29,3.924,,67.83,ABH,-1.57767,0.221079,0.00610411,1.0122 beta-lactamase_156_L191W,beta-lactamase_156_191,TEM-1,beta-lactamase_156,P62593,1.01221,NO,191,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.087,-5.14,4.053,,,H,A,0.55,0.09,1.372,,63.29,BHH,-1.445,0.111618,0.00263549,1.01221 beta-lactamase_0_R159D,beta-lactamase_0_159,TEM-1,beta-lactamase_0,P62593,1.01222,NO,159,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-0.94,-3.691,2.751,,0.316,,B,1.2,-0.55,1.426,,64.34,PBH,-1.011,0.0500837,0.00108472,1.01222 beta-lactamase_156_I285W,beta-lactamase_156_285,TEM-1,beta-lactamase_156,P62593,1.01222,NO,285,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.111618,0.101555,1.01222 beta-lactamase_39_N173R,beta-lactamase_39_173,TEM-1,beta-lactamase_39,P62593,1.01222,NO,173,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-2.663,-3.837,1.174,,1.044,T,l,0.61,1.25,1.426,,77.62,OPA,-1.46633,0.0495842,0.0033769,1.01222 beta-lactamase_156_P255Y,beta-lactamase_156_255,TEM-1,beta-lactamase_156,P62593,1.01223,NO,255,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.111618,0.00499612,1.01223 beta-lactamase_39_I258M,beta-lactamase_39_258,TEM-1,beta-lactamase_39,P62593,1.01223,NO,258,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.0495842,0.007931,1.01223 beta-lactamase_625_I285Q,beta-lactamase_625_285,TEM-1,beta-lactamase_625,P62593,1.01223,NO,285,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.213352,0.101555,1.01223 beta-lactamase_K109S,beta-lactamase_109,TEM-1,beta-lactamase,P62593,1.01223,NO,109,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.734,-2.861,1.127,6.05842,0.787,G,A,1.82,2.21,21.623,21.623,72.73,ABB,-1.63333,0.221079,0.00462493,1.01223 beta-lactamase_K53A,beta-lactamase_53,TEM-1,beta-lactamase,P62593,1.01223,NO,53,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-2.313,-2.735,0.422,5.93654,0.589,,B,1.82,1.15,19.72,19.72,77.62,OBH,-2.1,0.221079,0.00383383,1.01223 beta-lactamase_E145K,beta-lactamase_145,TEM-1,beta-lactamase,P62593,1.01224,NO,145,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.357,-3.472,1.115,5.38104,0.545,H,A,0.52,0.79,2.124,,77.62,BAH,-2.069,0.221079,0.00553285,1.01224 beta-lactamase_I171T,beta-lactamase_171,TEM-1,beta-lactamase,P62593,1.01224,NO,171,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-2.431,-2.05,-0.381,5.22771,0.361,,B,1,0.53,1.66,,77.62,HHO,-1.55533,0.221079,0.00623355,1.01224 kka2_1:8_E161W,kka2_1:8_161,Kka2,kka2_1:8,P00552,1.01224,NO,161,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.581,-5.534,3.953,,0.829,G,A,1.04,2.24,11.923,11.923,92.05,AAB,-1.861,0.100394,0.00760103,1.01224 kka2_1:8_E161W,kka2_1:8_161,Kka2,kka2_1:8,P00552,1.01224,NO,161,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.581,-5.534,3.953,,0.829,G,A,1.04,2.24,11.923,11.923,92.05,AAB,-1.861,0.100394,0.00760103,1.01224 beta-lactamase_0_T138Q,beta-lactamase_0_138,TEM-1,beta-lactamase_0,P62593,1.01225,NO,138,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.506,-3.82,1.314,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.0500837,0.00487868,1.01225 beta-lactamase_156_A84G,beta-lactamase_156_84,TEM-1,beta-lactamase_156,P62593,1.01225,NO,84,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.651,-3.358,1.707,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.111618,0.00503822,1.01225 beta-lactamase_156_R41T,beta-lactamase_156_41,TEM-1,beta-lactamase_156,P62593,1.01225,NO,41,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-0.942,-3.385,2.443,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.111618,0.00123327,1.01225 beta-lactamase_156_V106R,beta-lactamase_156_106,TEM-1,beta-lactamase_156,P62593,1.01225,NO,106,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.218,-4.201,2.983,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.111618,0.00304168,1.01225 beta-lactamase_2500_I245V,beta-lactamase_2500_245,TEM-1,beta-lactamase_2500,P62593,1.01225,NO,245,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.361275,0.00391032,1.01225 beta-lactamase_39_W288F,beta-lactamase_39_288,TEM-1,beta-lactamase_39,P62593,1.01225,NO,288,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,,,,,,,,,,,,,BHO,,0.0495842,,1.01225 beta-lactamase_625_A211I,beta-lactamase_625_211,TEM-1,beta-lactamase_625,P62593,1.01225,NO,211,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.896,-4.033,2.137,,0.369,T,A,0.46,-0.69,2.061,,77.62,AHA,-1.94633,0.213352,0.00648183,1.01225 beta-lactamase_39_M127W,beta-lactamase_39_127,TEM-1,beta-lactamase_39,P62593,1.01226,NO,127,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-2.251,-3.502,1.251,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.0495842,0.00437927,1.01226 beta-lactamase_156_E87F,beta-lactamase_156_87,TEM-1,beta-lactamase_156,P62593,1.01227,NO,87,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.421,-4.277,2.856,,0.048,,B,1.04,0.92,1.754,,64.69,PAP,-1.969,0.111618,0.00337888,1.01227 beta-lactamase_2500_E195H,beta-lactamase_2500_195,TEM-1,beta-lactamase_2500,P62593,1.01227,NO,195,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.186,-3.381,1.195,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.361275,0.00496565,1.01227 beta-lactamase_39_L188I,beta-lactamase_39_188,TEM-1,beta-lactamase_39,P62593,1.01227,NO,188,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.166,-2.584,1.418,,,H,A,0.55,-0.3,2.982,,60.14,PHB,-1.47033,0.0495842,0.00295687,1.01227 beta-lactamase_625_H151E,beta-lactamase_625_151,TEM-1,beta-lactamase_625,P62593,1.01227,NO,151,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-2.96,-3.258,0.298,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.213352,0.00216946,1.01227 beta-lactamase_625_P25F,beta-lactamase_625_25,TEM-1,beta-lactamase_625,P62593,1.01227,NO,25,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.526,-4.406,2.88,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.213352,0.00347571,1.01227 beta-lactamase_T186A,beta-lactamase_186,TEM-1,beta-lactamase,P62593,1.01227,NO,186,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.522,-1.898,-0.624,5.07364,0.396,H,A,0.3,-0.28,2.144,,77.62,HPP,-1.77633,0.221079,0.00485034,1.01227 PSD95pdz3_T385G,PSD95pdz3_385,PSD95pdz3,PSD95pdz3,P31016,1.01227,NO,385,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.533,-2.93,1.397,5.57157,,,,,23.6871,4.527,,87.71,PPH,-1.56567,0.0758425,0.000545119,1.01227 beta-lactamase_156_E119C,beta-lactamase_156_119,TEM-1,beta-lactamase_156,P62593,1.01229,NO,119,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.412,-5.165,3.753,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.111618,0.00386966,1.01229 beta-lactamase_156_L223N,beta-lactamase_156_223,TEM-1,beta-lactamase_156,P62593,1.01229,NO,223,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.055,-4.1,3.045,,0.27,,B,0.55,0.09,1.511,,74.48,HHO,-1.35033,0.111618,0.00372793,1.01229 beta-lactamase_625_A200F,beta-lactamase_625_200,TEM-1,beta-lactamase_625,P62593,1.01229,NO,200,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.878,-4.397,2.519,,0.757,H,A,0.46,-0.19,12.672,12.672,77.62,HHP,-2.001,0.213352,0.0060056,1.01229 beta-lactamase_2500_L199M,beta-lactamase_2500_199,TEM-1,beta-lactamase_2500,P62593,1.0123,NO,199,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-2.942,-4.728,1.786,,0.832,H,A,0.55,0.42,15.504,15.504,77.62,PHH,-2.32933,0.361275,0.0048649,1.0123 beta-lactamase_39_E145Q,beta-lactamase_39_145,TEM-1,beta-lactamase_39,P62593,1.0123,NO,145,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.357,-2.979,0.622,,0.545,H,A,1.04,0.79,1.199,,77.62,BAH,-2.069,0.0495842,0.00553285,1.0123 beta-lactamase_E108V,beta-lactamase_108,TEM-1,beta-lactamase,P62593,1.0123,NO,108,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.46,-3.706,2.246,5.52079,0.572,G,A,0.52,1.87,1.973,,72.73,PAB,-1.437,0.221079,0.00413372,1.0123 beta-lactamase_E26T,beta-lactamase_26,TEM-1,beta-lactamase,P62593,1.0123,NO,26,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.454,-2.753,0.299,,0.54,H,A,1.04,0.98,,,93.01,OAP,-1.96167,0.221079,0.00297948,1.0123 kka2_1:4_D134M,kka2_1:4_134,Kka2,kka2_1:4,P00552,1.01231,NO,134,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.969,-4.823,3.854,,0.421,B,B,0.75,0.31,0.733,,49.62,HAB,-1.057,0.168804,0.00270812,1.01231 Pab1_Q194L,Pab1_194,Pab1,Pab1,P04147,1.01231,NO,194,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.179,-2.195,0.016,,,,,,,,,,OPA,-1.59767,0.175299,0.0016145,1.01231 beta-lactamase_39_E46G,beta-lactamase_39_46,TEM-1,beta-lactamase_39,P62593,1.01232,NO,46,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.94,-2.778,0.838,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.0495842,0.00427568,1.01232 PSD95pdz3_Q358V,PSD95pdz3_358,PSD95pdz3,PSD95pdz3,P31016,1.01232,NO,358,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-1.699,-3.21,1.511,5.21282,,,,,14.8844,,,,APH,-1.531,0.0758425,0.000594893,1.01232 beta-lactamase_625_A148H,beta-lactamase_625_148,TEM-1,beta-lactamase_625,P62593,1.01235,NO,148,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.757,-3.344,1.587,,0.379,H,A,0.46,-0.55,1.359,,72.73,PHH,-1.40167,0.213352,0.00547053,1.01235 beta-lactamase_625_E166W,beta-lactamase_625_166,TEM-1,beta-lactamase_625,P62593,1.01235,NO,166,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.756,-5.495,3.739,,0.508,G,A,1.04,1.05,2.124,,73.08,OAH,-1.42233,0.213352,0.00512989,1.01235 beta-lactamase_0_G236L,beta-lactamase_0_236,TEM-1,beta-lactamase_0,P62593,1.01236,NO,236,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.784,-3.712,2.928,,0.241,,b,0.29,-0.59,3.506,,64.69,HOO,-1.025,0.0500837,0.00162372,1.01236 beta-lactamase_156_E166Y,beta-lactamase_156_166,TEM-1,beta-lactamase_156,P62593,1.01236,NO,166,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.756,-4.36,2.604,,0.508,G,A,1.04,1.05,2.393,,73.08,OAH,-1.42233,0.111618,0.00512989,1.01236 beta-lactamase_156_R41H,beta-lactamase_156_41,TEM-1,beta-lactamase_156,P62593,1.01236,NO,41,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-0.942,-4.279,3.337,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.111618,0.00123327,1.01236 beta-lactamase_625_L197K,beta-lactamase_625_197,TEM-1,beta-lactamase_625,P62593,1.01236,NO,197,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.853,-3.679,2.826,,0.007,S,B,0.55,0.33,1.756,,60.14,HHP,-1.833,0.213352,0.00144602,1.01236 beta-lactamase_625_E61H,beta-lactamase_625_61,TEM-1,beta-lactamase_625,P62593,1.01237,NO,61,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.115,-4.518,2.403,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.213352,0.00440955,1.01237 beta-lactamase_625_P60S,beta-lactamase_625_60,TEM-1,beta-lactamase_625,P62593,1.01237,NO,60,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-2.469,-2.362,-0.107,,0.256,T,A,0.52,-0.56,3.653,,77.62,BOA,-1.97633,0.213352,0.00521318,1.01237 beta-lactamase_625_Q88A,beta-lactamase_625_88,TEM-1,beta-lactamase_625,P62593,1.01237,NO,88,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.086,-2.75,0.664,,0.807,,B,0.64,2.03,1.84,,77.62,APH,-1.53433,0.213352,0.00504167,1.01237 beta-lactamase_625_L28E,beta-lactamase_625_28,TEM-1,beta-lactamase_625,P62593,1.01238,NO,28,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.579,-3.677,2.098,,0.277,H,A,0.55,-0.16,2.716,,93.01,PHH,-2.11333,0.213352,0.00359321,1.01238 beta-lactamase_I171G,beta-lactamase_171,TEM-1,beta-lactamase,P62593,1.01238,NO,171,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-2.431,-3.603,1.172,5.22771,0.361,,B,1,0.53,1.66,,77.62,HHO,-1.55533,0.221079,0.00623355,1.01238 gb1_K236T,gb1_236,gb1,gb1,P06654,1.01238,NO,236,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-2.119,-3.179,1.06,,,,,,,1.083,,45.54,OBP,-1.758,0.177985,0.00255408,1.01238 gb1_K276Q,gb1_276,gb1,gb1,P06654,1.01238,NO,276,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.456,-3.289,1.833,,,,,,,0.236,,12.72,PBP,-1.65133,0.177985,0.00620493,1.01238 beta-lactamase_39_A77E,beta-lactamase_39_77,TEM-1,beta-lactamase_39,P62593,1.01239,NO,77,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.234,-3.61,2.376,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.0495842,0.00282362,1.01239 beta-lactamase_39_E87L,beta-lactamase_39_87,TEM-1,beta-lactamase_39,P62593,1.01239,NO,87,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.421,-2.529,1.108,,0.048,,B,1.04,0.92,15.231,15.231,64.69,PAP,-1.969,0.0495842,0.00337888,1.01239 beta-lactamase_625_A183L,beta-lactamase_625_183,TEM-1,beta-lactamase_625,P62593,1.01239,NO,183,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.231,-3.283,2.052,,0.155,H,A,0.46,-0.91,23.859,23.859,77.62,HHH,-1.53367,0.213352,0.00296631,1.01239 beta-lactamase_39_E166S,beta-lactamase_39_166,TEM-1,beta-lactamase_39,P62593,1.0124,NO,166,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.756,-2.582,0.826,,0.508,G,A,1.04,1.05,17.227,17.227,73.08,OAH,-1.42233,0.0495842,0.00512989,1.0124 beta-lactamase_625_Q37L,beta-lactamase_625_37,TEM-1,beta-lactamase_625,P62593,1.0124,NO,37,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.134,-2.893,0.759,,0.613,H,A,0.64,1.98,1.318,,73.08,APH,-2.06967,0.213352,0.00425833,1.0124 kka2_1:4_C192I,kka2_1:4_192,Kka2,kka2_1:4,P00552,1.0124,NO,192,C,I,CI,Special,Hydrophobic,5.07,6.02,0.95,198,121,131,10,108.5,166.7,58.2,-1.067,-3.687,2.62,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.168804,0.00485428,1.0124 kka2_1:8_A166E,kka2_1:8_166,Kka2,kka2_1:8,P00552,1.0124,NO,166,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.407,-2.752,0.345,,0.534,,B,1.04,1.03,13.995,13.995,71.59,HHO,-2.421,0.100394,0.00799912,1.0124 kka2_1:8_A166E,kka2_1:8_166,Kka2,kka2_1:8,P00552,1.0124,NO,166,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.407,-2.752,0.345,,0.534,,B,1.04,1.03,13.995,13.995,71.59,HHO,-2.421,0.100394,0.00799912,1.0124 beta-lactamase_625_K30M,beta-lactamase_625_30,TEM-1,beta-lactamase_625,P62593,1.01242,NO,30,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-2.307,-4.578,2.271,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.213352,0.00448593,1.01242 Pab1_V148I,Pab1_148,Pab1,Pab1,P04147,1.01242,NO,148,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.875,-3.209,1.334,,,,,,,,,,PHH,-1.43033,0.175299,0.00179641,1.01242 beta-lactamase_156_G253K,beta-lactamase_156_253,TEM-1,beta-lactamase_156,P62593,1.01243,NO,253,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.111618,0.00786358,1.01243 beta-lactamase_156_L191I,beta-lactamase_156_191,TEM-1,beta-lactamase_156,P62593,1.01244,NO,191,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.087,-3.028,1.941,,,H,A,0.55,0.09,1.372,,63.29,BHH,-1.445,0.111618,0.00263549,1.01244 beta-lactamase_156_P105M,beta-lactamase_156_105,TEM-1,beta-lactamase_156,P62593,1.01244,NO,105,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.813,-4.702,3.889,,0.226,T,A,0.52,0.8,1.154,,63.29,POH,-1.01533,0.111618,0.0011981,1.01244 Pab1_Q194T,Pab1_194,Pab1,Pab1,P04147,1.01244,NO,194,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.179,-3.458,1.279,,,,,,,,,,OPA,-1.59767,0.175299,0.0016145,1.01244 beta-lactamase_625_L196F,beta-lactamase_625_196,TEM-1,beta-lactamase_625,P62593,1.01245,NO,196,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-2.478,-4.226,1.748,,0.518,S,A,0.55,1.35,12.152,12.152,77.62,AHH,-1.839,0.213352,0.00512144,1.01245 beta-lactamase_156_A200L,beta-lactamase_156_200,TEM-1,beta-lactamase_156,P62593,1.01246,NO,200,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.878,-3.527,1.649,,0.757,H,A,0.46,-0.19,16.368,16.368,77.62,HHP,-2.001,0.111618,0.0060056,1.01246 beta-lactamase_156_M67L,beta-lactamase_156_67,TEM-1,beta-lactamase_156,P62593,1.01246,NO,67,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-2.231,-2.657,0.426,,0.006,G,P,0.55,-0.81,1.463,,65.03,HHP,-1.502,0.111618,0.00409753,1.01246 beta-lactamase_39_L196P,beta-lactamase_39_196,TEM-1,beta-lactamase_39,P62593,1.01246,NO,196,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-2.478,-3.165,0.687,,0.518,S,A,0.55,1.35,12.152,12.152,77.62,AHH,-1.839,0.0495842,0.00512144,1.01246 beta-lactamase_156_T187N,beta-lactamase_156_187,TEM-1,beta-lactamase_156,P62593,1.01247,NO,187,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.401,-2.373,0.972,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.111618,0.00491782,1.01247 beta-lactamase_39_R220K,beta-lactamase_39_220,TEM-1,beta-lactamase_39,P62593,1.01247,NO,220,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-0.942,-2.865,1.923,,0.295,I,A,1.2,-0.76,1.596,,74.48,HBP,-1.33633,0.0495842,0.00232421,1.01247 beta-lactamase_D250E,beta-lactamase_250,TEM-1,beta-lactamase,P62593,1.01247,NO,250,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.335,-2.65,0.315,5.72026,0.89,T,L,0.23,1.53,24.737,24.737,66.08,OAO,-1.85133,0.221079,0.00550899,1.01247 beta-lactamase_P12M,beta-lactamase_12,TEM-1,beta-lactamase,P62593,1.01248,NO,12,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-2.016,-4.406,2.39,,,,,,,2.88,,72.73,HOH,-2.05167,0.221079,0.00241653,1.01248 beta-lactamase_39_N168T,beta-lactamase_39_168,TEM-1,beta-lactamase_39,P62593,1.0125,NO,168,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-1.029,-2.214,1.185,,0.113,G,A,0.61,-0.4,0.822,,44.41,HPA,-1.13233,0.0495842,0.00288667,1.0125 beta-lactamase_2500_S80Q,beta-lactamase_2500_80,TEM-1,beta-lactamase_2500,P62593,1.01251,NO,80,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.029,-3.941,1.912,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.361275,0.00565569,1.01251 beta-lactamase_39_T178C,beta-lactamase_39_178,TEM-1,beta-lactamase_39,P62593,1.01251,NO,178,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-0.791,-4.637,3.846,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.0495842,0.000684366,1.01251 kka2_1:8_P12M,kka2_1:8_12,Kka2,kka2_1:8,P00552,1.01251,NO,12,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.853,-4.703,3.85,,,.,B,0.52,1.25,2.41,,48.11,POH,-1.80767,0.100394,0.00500011,1.01251 kka2_1:8_P12M,kka2_1:8_12,Kka2,kka2_1:8,P00552,1.01251,NO,12,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.853,-4.703,3.85,,,.,B,0.52,1.25,2.41,,48.11,POH,-1.80767,0.100394,0.00500011,1.01251 beta-lactamase_39_E164Y,beta-lactamase_39_164,TEM-1,beta-lactamase_39,P62593,1.01252,NO,164,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-0.948,-4.233,3.285,,0.011,T,B,1.04,-0.4,0.664,,64.69,HAO,-1.388,0.0495842,0.00137286,1.01252 beta-lactamase_E270T,beta-lactamase_270,TEM-1,beta-lactamase,P62593,1.01252,NO,270,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.723,-2.295,0.572,5.33196,0.422,H,A,0.52,1.15,1.745,,64.34,AAB,-1.70933,0.221079,0.00767762,1.01252 beta-lactamase_156_F70V,beta-lactamase_156_70,TEM-1,beta-lactamase_156,P62593,1.01254,NO,70,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.169,-2.579,1.41,,,H,A,0.58,-1.34,1.918,,63.99,PHB,-0.980667,0.111618,0.00193499,1.01254 beta-lactamase_625_R118L,beta-lactamase_625_118,TEM-1,beta-lactamase_625,P62593,1.01254,NO,118,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.413,-2.872,0.459,,0.457,H,A,1.2,1.39,2.144,,77.62,HBA,-1.785,0.213352,0.00538794,1.01254 beta-lactamase_156_Q37K,beta-lactamase_156_37,TEM-1,beta-lactamase_156,P62593,1.01255,NO,37,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.134,-2.595,0.461,,0.613,H,A,0.64,1.98,12.052,12.052,73.08,APH,-2.06967,0.111618,0.00425833,1.01255 beta-lactamase_156_R202F,beta-lactamase_156_202,TEM-1,beta-lactamase_156,P62593,1.01255,NO,202,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.292,-4.334,3.042,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.111618,0.00321899,1.01255 beta-lactamase_39_A183T,beta-lactamase_39_183,TEM-1,beta-lactamase_39,P62593,1.01255,NO,183,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.231,-3.281,2.05,,0.155,H,A,0.46,-0.91,1.237,,77.62,HHH,-1.53367,0.0495842,0.00296631,1.01255 beta-lactamase_156_K53Y,beta-lactamase_156_53,TEM-1,beta-lactamase_156,P62593,1.01256,NO,53,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-2.313,-4.187,1.874,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.111618,0.00383383,1.01256 beta-lactamase_625_A124C,beta-lactamase_625_124,TEM-1,beta-lactamase_625,P62593,1.01256,NO,124,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.181,-4.594,3.413,,,H,A,0.46,-0.9,2.027,,64.34,HHH,-1.152,0.213352,0.00481399,1.01256 beta-lactamase_156_H94S,beta-lactamase_156_94,TEM-1,beta-lactamase_156,P62593,1.01257,NO,94,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-2.5,-3.499,0.999,,0.776,,B,0.17,1.24,11.583,11.583,77.62,HBH,-1.872,0.111618,0.00389226,1.01257 beta-lactamase_156_L192Y,beta-lactamase_156_192,TEM-1,beta-lactamase_156,P62593,1.01257,NO,192,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.254,-3.913,2.659,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.111618,0.00558728,1.01257 beta-lactamase_156_R41Y,beta-lactamase_156_41,TEM-1,beta-lactamase_156,P62593,1.01257,NO,41,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-0.942,-4.188,3.246,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.111618,0.00123327,1.01257 beta-lactamase_156_S241N,beta-lactamase_156_241,TEM-1,beta-lactamase_156,P62593,1.01257,NO,241,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.111618,0.00452736,1.01257 Pab1_N162E,Pab1_162,Pab1,Pab1,P04147,1.01257,NO,162,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-2.313,-2.696,0.383,,0.681,T,A,,1.12,,,,APO,-1.532,0.175299,0.0030719,1.01257 beta-lactamase_T112S,beta-lactamase_112,TEM-1,beta-lactamase,P62593,1.01258,NO,112,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.186,-2.762,0.576,6.47162,0.921,T,A,0.77,1.06,2.04,,73.78,HPA,-1.925,0.221079,0.00531334,1.01258 beta-lactamase_156_A182T,beta-lactamase_156_182,TEM-1,beta-lactamase_156,P62593,1.01259,NO,182,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.777,-2.685,0.908,,0.136,H,A,0.46,-0.66,16.784,16.784,93.01,OHH,-1.27367,0.111618,0.00559099,1.01259 beta-lactamase_39_P60T,beta-lactamase_39_60,TEM-1,beta-lactamase_39,P62593,1.01259,NO,60,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-2.469,-3.483,1.014,,0.256,T,A,0.52,-0.56,21.37,21.37,77.62,BOA,-1.97633,0.0495842,0.00521318,1.01259 beta-lactamase_625_A200L,beta-lactamase_625_200,TEM-1,beta-lactamase_625,P62593,1.01259,NO,200,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.878,-3.527,1.649,,0.757,H,A,0.46,-0.19,12.672,12.672,77.62,HHP,-2.001,0.213352,0.0060056,1.01259 beta-lactamase_156_L197F,beta-lactamase_156_197,TEM-1,beta-lactamase_156,P62593,1.0126,NO,197,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.853,-3.685,2.832,,0.007,S,B,0.55,0.33,1.58,,60.14,HHP,-1.833,0.111618,0.00144602,1.0126 beta-lactamase_39_P143I,beta-lactamase_39_143,TEM-1,beta-lactamase_39,P62593,1.0126,NO,143,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.967,-2.787,1.82,,0.075,H,A,0.52,-0.37,0.976,,66.78,OOB,-1.354,0.0495842,0.00114551,1.0126 beta-lactamase_625_T126C,beta-lactamase_625_126,TEM-1,beta-lactamase_625,P62593,1.0126,NO,126,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.122,-4.816,3.694,,0.05,H,A,0.22,-0.05,0.817,,44.41,HPH,-1.60467,0.213352,0.00244552,1.0126 beta-lactamase_156_R273E,beta-lactamase_156_273,TEM-1,beta-lactamase_156,P62593,1.01261,NO,273,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.314,-2.209,-0.105,,0.564,H,A,1.2,1.57,20.248,20.248,73.78,ABP,-1.841,0.111618,0.0077952,1.01261 beta-lactamase_39_R162H,beta-lactamase_39_162,TEM-1,beta-lactamase_39,P62593,1.01263,NO,162,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.016,-4.37,3.354,,0.124,S,B,1.2,-0.37,31.656,31.656,64.69,ABH,-1.25,0.0495842,0.000561334,1.01263 beta-lactamase_625_K53R,beta-lactamase_625_53,TEM-1,beta-lactamase_625,P62593,1.01263,NO,53,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-2.313,-2.027,-0.286,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.213352,0.00383383,1.01263 PSD95pdz3_V365A,PSD95pdz3_365,PSD95pdz3,PSD95pdz3,P31016,1.01263,NO,365,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.592,-1.726,0.134,5.03791,,,,,18.9657,2.364,,81.35,OHA,-1.288,0.0758425,0.000649764,1.01263 beta-lactamase_156_A185C,beta-lactamase_156_185,TEM-1,beta-lactamase_156,P62593,1.01264,NO,185,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.406,-4.699,3.293,,,H,A,0.46,-1.02,0.365,,65.03,HHP,-1.84033,0.111618,0.00467449,1.01264 beta-lactamase_A123A,beta-lactamase_123,TEM-1,beta-lactamase,P62593,1.01264,NO,123,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.834,-0.834,,4.70061,0.039,H,A,0.52,-0.72,0.705,,41.26,PHH,-1.47367,0.221079,0.0010157,1.01264 beta-lactamase_L38L,beta-lactamase_38,TEM-1,beta-lactamase,P62593,1.01264,NO,38,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.343,-1.343,,5.23728,0.088,H,A,1.75,0.2,1.986,,64.34,PHO,-1.78033,0.221079,0.00373244,1.01264 beta-lactamase_625_T138H,beta-lactamase_625_138,TEM-1,beta-lactamase_625,P62593,1.01267,NO,138,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.506,-4.649,2.143,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.213352,0.00487868,1.01267 beta-lactamase_156_M180H,beta-lactamase_156_180,TEM-1,beta-lactamase_156,P62593,1.01268,NO,180,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-2.795,-4.627,1.832,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.111618,0.00552048,1.01268 beta-lactamase_156_M67S,beta-lactamase_156_67,TEM-1,beta-lactamase_156,P62593,1.01268,NO,67,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-2.231,-2.445,0.214,,0.006,G,P,0.55,-0.81,1.463,,65.03,HHP,-1.502,0.111618,0.00409753,1.01268 kka2_1:4_L158R,kka2_1:4_158,Kka2,kka2_1:4,P00552,1.01268,NO,158,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.947,-4.189,2.242,,0.095,,B,1.59,0.77,7.588,,63.64,AHA,-1.25333,0.168804,0.00529068,1.01268 beta-lactamase_156_Q88W,beta-lactamase_156_88,TEM-1,beta-lactamase_156,P62593,1.01269,NO,88,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.086,-5.502,3.416,,0.807,,B,0.64,2.03,0.911,,77.62,APH,-1.53433,0.111618,0.00504167,1.01269 beta-lactamase_39_P143N,beta-lactamase_39_143,TEM-1,beta-lactamase_39,P62593,1.01269,NO,143,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.967,-3.954,2.987,,0.075,H,A,0.52,-0.37,0.976,,66.78,OOB,-1.354,0.0495842,0.00114551,1.01269 beta-lactamase_156_D99P,beta-lactamase_156_99,TEM-1,beta-lactamase_156,P62593,1.0127,NO,99,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.191,-3.8,2.609,,0.402,G,A,0.75,0.36,3.529,,64.69,PAH,-1.794,0.111618,0.00305446,1.0127 beta-lactamase_39_I285F,beta-lactamase_39_285,TEM-1,beta-lactamase_39,P62593,1.0127,NO,285,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.0495842,0.101555,1.0127 beta-lactamase_39_A170M,beta-lactamase_39_170,TEM-1,beta-lactamase_39,P62593,1.01271,NO,170,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.237,-4.595,3.358,,0.126,,L,0.46,-0.35,3.7,,64.69,AHH,-1.63267,0.0495842,0.00431903,1.01271 beta-lactamase_39_H151D,beta-lactamase_39_151,TEM-1,beta-lactamase_39,P62593,1.01273,NO,151,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-2.96,-3.624,0.664,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.0495842,0.00216946,1.01273 beta-lactamase_A200E,beta-lactamase_200,TEM-1,beta-lactamase,P62593,1.01273,NO,200,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.878,-2.662,0.784,5.19406,0.757,H,A,0.47,-0.19,0.436,,77.62,HHP,-2.001,0.221079,0.0060056,1.01273 beta-lactamase_A211R,beta-lactamase_211,TEM-1,beta-lactamase,P62593,1.01273,NO,211,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.896,-3.077,1.181,5.54662,0.369,T,A,0.52,-0.69,2.061,,77.62,AHA,-1.94633,0.221079,0.00648183,1.01273 beta-lactamase_A230C,beta-lactamase_230,TEM-1,beta-lactamase,P62593,1.01273,NO,230,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.154,-4.695,3.541,4.54336,0.01,E,B,0.75,-1.17,1.97,,50,HHA,-1.079,0.221079,0.00516841,1.01273 beta-lactamase_D33K,beta-lactamase_33,TEM-1,beta-lactamase,P62593,1.01273,NO,33,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.321,-3.459,1.138,5.05203,0.366,H,A,0.23,0.33,2.032,,77.62,BAH,-2.12133,0.221079,0.00435556,1.01273 beta-lactamase_E108E,beta-lactamase_108,TEM-1,beta-lactamase,P62593,1.01273,NO,108,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.46,-1.46,,5.52079,0.572,G,A,0.52,1.87,1.973,,72.73,PAB,-1.437,0.221079,0.00413372,1.01273 beta-lactamase_H151A,beta-lactamase_151,TEM-1,beta-lactamase,P62593,1.01273,NO,151,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-2.96,-3.11,0.15,5.47408,0.594,H,A,0.35,0.1,1.843,,77.62,HBP,-2.34767,0.221079,0.00216946,1.01273 beta-lactamase_I171K,beta-lactamase_171,TEM-1,beta-lactamase,P62593,1.01273,NO,171,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-2.431,-2.528,0.097,5.22771,0.361,,B,1,0.53,1.66,,77.62,HHO,-1.55533,0.221079,0.00623355,1.01273 beta-lactamase_N98H,beta-lactamase_98,TEM-1,beta-lactamase,P62593,1.01273,NO,98,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-2.973,-3.344,0.371,6.59973,0.963,G,A,1.07,1.35,1.332,,77.62,PPA,-2.07867,0.221079,0.00505389,1.01273 beta-lactamase_P217M,beta-lactamase_217,TEM-1,beta-lactamase,P62593,1.01273,NO,217,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-2.062,-4.835,2.773,5.19872,0.496,I,A,0.99,-0.33,0.431,,74.48,OOH,-1.64333,0.221079,0.00463211,1.01273 beta-lactamase_Q37L,beta-lactamase_37,TEM-1,beta-lactamase,P62593,1.01273,NO,37,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.134,-2.893,0.759,5.69153,0.613,H,A,0.12,1.98,1.318,,73.08,APH,-2.06967,0.221079,0.00425833,1.01273 beta-lactamase_R7Q,beta-lactamase_7,TEM-1,beta-lactamase,P62593,1.01273,NO,7,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.683,-3.696,2.013,,,,,,,2.44,,67.13,HBH,-1.96267,0.221079,0.00211375,1.01273 beta-lactamase_T262H,beta-lactamase_262,TEM-1,beta-lactamase,P62593,1.01273,NO,262,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.332,-4.65,3.318,5.06002,0.108,E,B,0.3,-0.55,1.423,,67.83,PPO,-2.081,0.221079,0.00853516,1.01273 beta-lactamase_V106E,beta-lactamase_106,TEM-1,beta-lactamase,P62593,1.01273,NO,106,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.218,-3.859,2.641,5.23115,0.258,T,A,0.96,0.24,1.188,,72.73,OHP,-1.04933,0.221079,0.00304168,1.01273 beta-lactamase_V29I,beta-lactamase_29,TEM-1,beta-lactamase,P62593,1.01273,NO,29,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-2.856,-3.928,1.072,5.58481,0.733,H,A,0.23,-0.78,1.287,,93.01,HHB,-2.24733,0.221079,0.00318969,1.01273 beta-lactamase_39_M67S,beta-lactamase_39_67,TEM-1,beta-lactamase_39,P62593,1.01274,NO,67,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-2.231,-2.445,0.214,,0.006,G,P,0.55,-0.81,1.463,,65.03,HHP,-1.502,0.0495842,0.00409753,1.01274 beta-lactamase_625_N50S,beta-lactamase_625_50,TEM-1,beta-lactamase_625,P62593,1.01274,NO,50,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-2.979,-3.331,0.352,,0.912,T,A,0.61,1.24,3.446,,77.62,HPP,-2.134,0.213352,0.0047211,1.01274 beta-lactamase_2500_R189K,beta-lactamase_2500_189,TEM-1,beta-lactamase_2500,P62593,1.01275,NO,189,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.844,-2.391,0.547,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.361275,0.0050699,1.01275 beta-lactamase_625_A182Q,beta-lactamase_625_182,TEM-1,beta-lactamase_625,P62593,1.01275,NO,182,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.777,-3.097,1.32,,0.136,H,A,0.46,-0.66,16.784,16.784,93.01,OHH,-1.27367,0.213352,0.00559099,1.01275 beta-lactamase_625_Q88F,beta-lactamase_625_88,TEM-1,beta-lactamase_625,P62593,1.01275,NO,88,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.086,-4.377,2.291,,0.807,,B,0.64,2.03,1.84,,77.62,APH,-1.53433,0.213352,0.00504167,1.01275 beta-lactamase_156_A268C,beta-lactamase_156_268,TEM-1,beta-lactamase_156,P62593,1.01276,NO,268,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.111618,0.0102525,1.01276 beta-lactamase_625_E210K,beta-lactamase_625_210,TEM-1,beta-lactamase_625,P62593,1.01276,NO,210,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.319,-2.868,0.549,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.213352,0.00663582,1.01276 PSD95pdz3_A347T,PSD95pdz3_347,PSD95pdz3,PSD95pdz3,P31016,1.01276,NO,347,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.307,-2.878,1.571,4.89689,,,,,15.176,,,,OHA,-1.269,0.0758425,0.00074525,1.01276 beta-lactamase_625_A200R,beta-lactamase_625_200,TEM-1,beta-lactamase_625,P62593,1.01277,NO,200,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.878,-2.634,0.756,,0.757,H,A,0.46,-0.19,12.672,12.672,77.62,HHP,-2.001,0.213352,0.0060056,1.01277 beta-lactamase_156_G142Q,beta-lactamase_156_142,TEM-1,beta-lactamase_156,P62593,1.01278,NO,142,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.707,-4.087,3.38,,0.034,,p,0.29,-0.64,0.325,,64.69,OOO,-0.834,0.111618,0.00060149,1.01278 beta-lactamase_156_E145W,beta-lactamase_156_145,TEM-1,beta-lactamase_156,P62593,1.01279,NO,145,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.357,-5.352,2.995,,0.545,H,A,1.04,0.79,3.661,,77.62,BAH,-2.069,0.111618,0.00553285,1.01279 beta-lactamase_625_I285T,beta-lactamase_625_285,TEM-1,beta-lactamase_625,P62593,1.01279,NO,285,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.213352,0.101555,1.01279 beta-lactamase_625_L150Y,beta-lactamase_625_150,TEM-1,beta-lactamase_625,P62593,1.01279,NO,150,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.326,-4.133,2.807,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.213352,0.00463171,1.01279 beta-lactamase_156_A211T,beta-lactamase_156_211,TEM-1,beta-lactamase_156,P62593,1.0128,NO,211,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.896,-2.901,1.005,,0.369,T,A,0.46,-0.69,8.527,8.527,77.62,AHA,-1.94633,0.111618,0.00648183,1.0128 beta-lactamase_156_A77M,beta-lactamase_156_77,TEM-1,beta-lactamase_156,P62593,1.0128,NO,77,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.234,-4.524,3.29,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.111618,0.00282362,1.0128 beta-lactamase_156_R118F,beta-lactamase_156_118,TEM-1,beta-lactamase_156,P62593,1.0128,NO,118,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.413,-4.338,1.925,,0.457,H,A,1.2,1.39,2.231,,77.62,HBA,-1.785,0.111618,0.00538794,1.0128 beta-lactamase_625_I45V,beta-lactamase_625_45,TEM-1,beta-lactamase_625,P62593,1.0128,NO,45,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-2.421,-2.178,-0.243,,,E,B,0.48,-0.3,3.642,,77.62,HHA,-2.30267,0.213352,0.00452842,1.0128 beta-lactamase_39_G141R,beta-lactamase_39_141,TEM-1,beta-lactamase_39,P62593,1.01281,NO,141,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.828,-3.94,3.112,,0.575,T,l,0.29,-0.28,0.722,,64.69,HOO,-1.08933,0.0495842,0.0012419,1.01281 kka2_1:1_I29Q,kka2_1:1_29,Kka2,kka2_1:1,P00552,1.01281,NO,29,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.692,-2.968,1.276,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.520039,0.00619521,1.01281 beta-lactamase_39_S201W,beta-lactamase_39_201,TEM-1,beta-lactamase_39,P62593,1.01282,NO,201,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.183,-5.344,4.161,,0.064,H,A,0.27,-0.07,3.54,,64.69,HPB,-1.451,0.0495842,0.00198815,1.01282 beta-lactamase_625_G243C,beta-lactamase_625_243,TEM-1,beta-lactamase_625,P62593,1.01282,NO,243,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.213352,0.00464034,1.01282 beta-lactamase_156_A182C,beta-lactamase_156_182,TEM-1,beta-lactamase_156,P62593,1.01283,NO,182,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.777,-5.025,3.248,,0.136,H,A,0.46,-0.66,16.784,16.784,93.01,OHH,-1.27367,0.111618,0.00559099,1.01283 beta-lactamase_156_M127N,beta-lactamase_156_127,TEM-1,beta-lactamase_156,P62593,1.01283,NO,127,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-2.251,-4.047,1.796,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.111618,0.00437927,1.01283 beta-lactamase_39_G194L,beta-lactamase_39_194,TEM-1,beta-lactamase_39,P62593,1.01283,NO,194,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.396,-3.731,2.335,,0.276,S,b,0.29,0.36,4.852,,67.83,POA,-1.832,0.0495842,0.00392163,1.01283 beta-lactamase_625_N50L,beta-lactamase_625_50,TEM-1,beta-lactamase_625,P62593,1.01283,NO,50,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-2.979,-2.892,-0.087,,0.912,T,A,0.61,1.24,3.446,,77.62,HPP,-2.134,0.213352,0.0047211,1.01283 beta-lactamase_156_V29L,beta-lactamase_156_29,TEM-1,beta-lactamase_156,P62593,1.01284,NO,29,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-2.856,-3.547,0.691,,0.733,H,A,0.44,-0.78,3.685,,93.01,HHB,-2.24733,0.111618,0.00318969,1.01284 beta-lactamase_2500_T186W,beta-lactamase_2500_186,TEM-1,beta-lactamase_2500,P62593,1.01284,NO,186,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.522,-5.446,2.924,,0.396,H,A,0.22,-0.28,2.144,,77.62,HPP,-1.77633,0.361275,0.00485034,1.01284 beta-lactamase_P217A,beta-lactamase_217,TEM-1,beta-lactamase,P62593,1.01284,NO,217,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-2.062,-1.891,-0.171,5.19872,0.496,I,A,0.99,-0.33,0.431,,74.48,OOH,-1.64333,0.221079,0.00463211,1.01284 beta-lactamase_156_P60D,beta-lactamase_156_60,TEM-1,beta-lactamase_156,P62593,1.01285,NO,60,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-2.469,-3.676,1.207,,0.256,T,A,0.52,-0.56,2.947,,77.62,BOA,-1.97633,0.111618,0.00521318,1.01285 beta-lactamase_39_D174T,beta-lactamase_39_174,TEM-1,beta-lactamase_39,P62593,1.01285,NO,174,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.738,-3.421,2.683,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.0495842,0.00125633,1.01285 beta-lactamase_39_L197Y,beta-lactamase_39_197,TEM-1,beta-lactamase_39,P62593,1.01285,NO,197,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.853,-3.986,3.133,,0.007,S,B,0.55,0.33,1.559,,60.14,HHP,-1.833,0.0495842,0.00144602,1.01285 beta-lactamase_K109R,beta-lactamase_109,TEM-1,beta-lactamase,P62593,1.01285,NO,109,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.734,-2.595,0.861,6.05842,0.787,G,A,1.82,2.21,21.623,21.623,72.73,ABB,-1.63333,0.221079,0.00462493,1.01285 PSD95pdz3_D348G,PSD95pdz3_348,PSD95pdz3,PSD95pdz3,P31016,1.01285,NO,348,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.264,-2.815,1.551,5.02473,,,,,16.8925,,,,HAH,-1.306,0.0758425,0.000731866,1.01285 PSD95pdz3_L349A,PSD95pdz3_349,PSD95pdz3,PSD95pdz3,P31016,1.01285,NO,349,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.347,-2.759,1.412,5.14696,,,,,24.6438,,,,AHP,-1.37667,0.0758425,0.00071841,1.01285 beta-lactamase_G90D,beta-lactamase_90,TEM-1,beta-lactamase,P62593,1.01286,NO,90,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-2.091,-2.02,-0.071,5.51991,0.598,T,A,0.23,0.32,1.791,,77.62,HOB,-1.52633,0.221079,0.00490273,1.01286 beta-lactamase_39_E87W,beta-lactamase_39_87,TEM-1,beta-lactamase_39,P62593,1.01287,NO,87,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.421,-5.437,4.016,,0.048,,B,1.04,0.92,15.231,15.231,64.69,PAP,-1.969,0.0495842,0.00337888,1.01287 beta-lactamase_625_I280M,beta-lactamase_625_280,TEM-1,beta-lactamase_625,P62593,1.01287,NO,280,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.213352,0.0530888,1.01287 beta-lactamase_M180K,beta-lactamase_180,TEM-1,beta-lactamase,P62593,1.01288,NO,180,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-2.795,-3.525,0.73,4.96809,0.242,,B,1.07,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.221079,0.00552048,1.01288 beta-lactamase_0_W163K,beta-lactamase_0_163,TEM-1,beta-lactamase_0,P62593,1.01289,NO,163,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-1.843,-2.971,1.128,,0.467,,B,0.47,-0.5,13.843,13.843,63.99,BHA,-1.269,0.0500837,0.00418955,1.01289 beta-lactamase_N173G,beta-lactamase_173,TEM-1,beta-lactamase,P62593,1.01289,NO,173,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-2.663,-1.002,-1.661,7.02497,1.044,T,l,0.09,1.25,1.88,,77.62,OPA,-1.46633,0.221079,0.0033769,1.01289 beta-lactamase_156_R41D,beta-lactamase_156_41,TEM-1,beta-lactamase_156,P62593,1.0129,NO,41,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-0.942,-3.657,2.715,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.111618,0.00123327,1.0129 beta-lactamase_39_I285Y,beta-lactamase_39_285,TEM-1,beta-lactamase_39,P62593,1.0129,NO,285,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.0495842,0.101555,1.0129 beta-lactamase_L47V,beta-lactamase_47,TEM-1,beta-lactamase,P62593,1.0129,NO,47,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.876,-2.564,0.688,5.27297,0.007,E,B,1.07,0.2,1.244,,67.83,AHA,-1.639,0.221079,0.00439844,1.0129 beta-lactamase_625_E210H,beta-lactamase_625_210,TEM-1,beta-lactamase_625,P62593,1.01291,NO,210,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.319,-4.778,2.459,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.213352,0.00663582,1.01291 beta-lactamase_156_E166W,beta-lactamase_156_166,TEM-1,beta-lactamase_156,P62593,1.01292,NO,166,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.756,-5.495,3.739,,0.508,G,A,1.04,1.05,2.393,,73.08,OAH,-1.42233,0.111618,0.00512989,1.01292 beta-lactamase_625_K53S,beta-lactamase_625_53,TEM-1,beta-lactamase_625,P62593,1.01292,NO,53,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-2.313,-2.879,0.566,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.213352,0.00383383,1.01292 PSD95pdz3_I338M,PSD95pdz3_338,PSD95pdz3,PSD95pdz3,P31016,1.01292,NO,338,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.63,-3.712,2.082,5.45113,,,,,13.0087,,,,HHP,-1.55767,0.0758425,0.000862587,1.01292 beta-lactamase_N173E,beta-lactamase_173,TEM-1,beta-lactamase,P62593,1.01293,NO,173,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-2.663,-3.453,0.79,7.02497,1.044,T,l,0.09,1.25,1.88,,77.62,OPA,-1.46633,0.221079,0.0033769,1.01293 PSD95pdz3_S371Y,PSD95pdz3_371,PSD95pdz3,PSD95pdz3,P31016,1.01293,NO,371,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.86,-3.939,2.079,5.19744,,,,,17.1117,3.854,,87.71,HPB,-1.598,0.0758425,0.000847873,1.01293 beta-lactamase_39_A278L,beta-lactamase_39_278,TEM-1,beta-lactamase_39,P62593,1.01294,NO,278,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.0495842,0.0310297,1.01294 beta-lactamase_T267P,beta-lactamase_267,TEM-1,beta-lactamase,P62593,1.01294,NO,267,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.308,-3.021,0.713,5.28263,0.54,,B,0.69,-0.14,0.374,,73.78,HPH,-1.9,0.221079,0.0102128,1.01294 beta-lactamase_625_A183K,beta-lactamase_625_183,TEM-1,beta-lactamase_625,P62593,1.01295,NO,183,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.231,-3.508,2.277,,0.155,H,A,0.46,-0.91,23.859,23.859,77.62,HHH,-1.53367,0.213352,0.00296631,1.01295 beta-lactamase_625_E61S,beta-lactamase_625_61,TEM-1,beta-lactamase_625,P62593,1.01295,NO,61,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.115,-2.688,0.573,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.213352,0.00440955,1.01295 Pab1_T145S,Pab1_145,Pab1,Pab1,P04147,1.01295,NO,145,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.067,-2.753,1.686,,0.237,H,A,0.3,0.69,,,,APH,-1.135,0.175299,0.000331088,1.01295 beta-lactamase_156_T193C,beta-lactamase_156_193,TEM-1,beta-lactamase_156,P62593,1.01296,NO,193,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.914,-4.857,2.943,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.111618,0.00482669,1.01296 beta-lactamase_39_A123W,beta-lactamase_39_123,TEM-1,beta-lactamase_39,P62593,1.01297,NO,123,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.834,-5.348,4.514,,0.039,H,A,0.46,-0.72,0.705,,41.26,PHH,-1.47367,0.0495842,0.0010157,1.01297 kka2_1:8_V84F,kka2_1:8_84,Kka2,kka2_1:8,P00552,1.01298,NO,84,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-2.279,-4.266,1.987,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.100394,0.00724019,1.01298 kka2_1:8_V84F,kka2_1:8_84,Kka2,kka2_1:8,P00552,1.01298,NO,84,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-2.279,-4.266,1.987,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.100394,0.00724019,1.01298 beta-lactamase_0_T263C,beta-lactamase_0_263,TEM-1,beta-lactamase_0,P62593,1.01299,NO,263,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.0500837,0.0110582,1.01299 beta-lactamase_625_L223S,beta-lactamase_625_223,TEM-1,beta-lactamase_625,P62593,1.01299,NO,223,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.055,-3.587,2.532,,0.27,,B,0.55,0.09,1.633,,74.48,HHO,-1.35033,0.213352,0.00372793,1.01299 beta-lactamase_A15V,beta-lactamase_15,TEM-1,beta-lactamase,P62593,1.01299,NO,15,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.654,-2.505,0.851,,,,,,,31.998,31.998,93.01,HHH,-2.10833,0.221079,0.00248966,1.01299 kka2_1:8_P179Y,kka2_1:8_179,Kka2,kka2_1:8,P00552,1.01299,NO,179,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.974,-4.379,3.405,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.100394,0.00298346,1.01299 kka2_1:8_P179Y,kka2_1:8_179,Kka2,kka2_1:8,P00552,1.01299,NO,179,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.974,-4.379,3.405,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.100394,0.00298346,1.01299 beta-lactamase_156_C121I,beta-lactamase_156_121,TEM-1,beta-lactamase_156,P62593,1.013,NO,121,C,I,CI,Special,Hydrophobic,5.07,6.02,0.95,198,121,131,10,108.5,166.7,58.2,-0.953,-3.628,2.675,,,H,A,0.46,-0.81,1.136,,63.29,HOP,-1.46767,0.111618,0.000744322,1.013 beta-lactamase_39_H151T,beta-lactamase_39_151,TEM-1,beta-lactamase_39,P62593,1.01301,NO,151,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-2.96,-3.492,0.532,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.0495842,0.00216946,1.01301 Pab1_D160S,Pab1_160,Pab1,Pab1,P04147,1.01301,NO,160,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.985,-2.978,1.993,,0.396,B,B,,1.12,,,,PAA,-1.30133,0.175299,0.000311977,1.01301 PSD95pdz3_L349H,PSD95pdz3_349,PSD95pdz3,PSD95pdz3,P31016,1.01301,NO,349,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.347,-4.587,3.24,5.14696,,,,,24.6438,,,,AHP,-1.37667,0.0758425,0.00071841,1.01301 beta-lactamase_39_K109Q,beta-lactamase_39_109,TEM-1,beta-lactamase_39,P62593,1.01302,NO,109,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.734,-2.855,1.121,,0.787,G,A,2.34,2.21,7.243,,72.73,ABB,-1.63333,0.0495842,0.00462493,1.01302 beta-lactamase_39_R63E,beta-lactamase_39_63,TEM-1,beta-lactamase_39,P62593,1.01302,NO,63,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-0.943,-3.298,2.355,,0.218,,B,1.2,-0.31,0.326,,44.06,ABH,-0.992333,0.0495842,0.00126938,1.01302 beta-lactamase_39_T187V,beta-lactamase_39_187,TEM-1,beta-lactamase_39,P62593,1.01302,NO,187,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.401,-3.287,1.886,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.0495842,0.00491782,1.01302 beta-lactamase_S96N,beta-lactamase_96,TEM-1,beta-lactamase,P62593,1.01302,NO,96,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.27,-3.037,0.767,5.29889,0.368,,b,0.25,0.39,32.348,32.348,73.78,HPP,-2.019,0.221079,0.00551835,1.01302 kka2_1:4_Q61G,kka2_1:4_61,Kka2,kka2_1:4,P00552,1.01302,NO,61,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.982,-2.486,-0.496,,0.591,H,A,0.64,0.41,3.484,,65.53,HPA,-1.85667,0.168804,0.00612092,1.01302 beta-lactamase_39_F58A,beta-lactamase_39_58,TEM-1,beta-lactamase_39,P62593,1.01303,NO,58,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-2.914,-3.389,0.475,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.0495842,0.00523369,1.01303 beta-lactamase_39_L28Y,beta-lactamase_39_28,TEM-1,beta-lactamase_39,P62593,1.01303,NO,28,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.579,-4.094,2.515,,0.277,H,A,0.55,-0.16,3.262,,93.01,PHH,-2.11333,0.0495842,0.00359321,1.01303 beta-lactamase_39_T126K,beta-lactamase_39_126,TEM-1,beta-lactamase_39,P62593,1.01303,NO,126,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.122,-3.536,2.414,,0.05,H,A,0.22,-0.05,0.586,,44.41,HPH,-1.60467,0.0495842,0.00244552,1.01303 kka2_1:8_I141Q,kka2_1:8_141,Kka2,kka2_1:8,P00552,1.01303,NO,141,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.495,-4.325,2.83,,0.068,H,A,1.52,-0.01,2.144,,92.05,BHA,-1.689,0.100394,0.00744745,1.01303 kka2_1:8_I141Q,kka2_1:8_141,Kka2,kka2_1:8,P00552,1.01303,NO,141,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.495,-4.325,2.83,,0.068,H,A,1.52,-0.01,2.144,,92.05,BHA,-1.689,0.100394,0.00744745,1.01303 beta-lactamase_156_T186H,beta-lactamase_156_186,TEM-1,beta-lactamase_156,P62593,1.01304,NO,186,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.522,-4.717,2.195,,0.396,H,A,0.22,-0.28,16.606,16.606,77.62,HPP,-1.77633,0.111618,0.00485034,1.01304 beta-lactamase_39_I125C,beta-lactamase_39_125,TEM-1,beta-lactamase_39,P62593,1.01304,NO,125,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.441,-4.783,3.342,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.0495842,0.00383964,1.01304 beta-lactamase_39_L167A,beta-lactamase_39_167,TEM-1,beta-lactamase_39,P62593,1.01304,NO,167,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.138,-3.097,1.959,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.0495842,0.00303566,1.01304 PSD95pdz3_S320F,PSD95pdz3_320,PSD95pdz3,PSD95pdz3,P31016,1.01304,NO,320,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.519,-3.749,2.23,5.81757,,,,,21.4517,,,,OPP,-1.306,0.0758425,0.00108158,1.01304 beta-lactamase_39_F64I,beta-lactamase_39_64,TEM-1,beta-lactamase_39,P62593,1.01305,NO,64,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-0.841,-3.335,2.494,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.0495842,0.000947691,1.01305 beta-lactamase_625_I54N,beta-lactamase_625_54,TEM-1,beta-lactamase_625,P62593,1.01305,NO,54,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-2.838,-2.849,0.011,,0.669,E,B,0.48,-0.14,3.946,,73.78,BHH,-2.337,0.213352,0.00403589,1.01305 beta-lactamase_625_Q97N,beta-lactamase_625_97,TEM-1,beta-lactamase_625,P62593,1.01305,NO,97,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.072,-3.773,1.701,,0.823,G,A,0.64,2.42,16.954,16.954,77.62,PPP,-2.43833,0.213352,0.0045116,1.01305 PSD95pdz3_T321F,PSD95pdz3_321,PSD95pdz3,PSD95pdz3,P31016,1.01305,NO,321,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.391,-3.749,2.358,5.19953,,,,,20.3371,,,,PPO,-1.306,0.0758425,0.00106992,1.01305 beta-lactamase_156_E61H,beta-lactamase_156_61,TEM-1,beta-lactamase_156,P62593,1.01306,NO,61,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.115,-4.518,2.403,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.111618,0.00440955,1.01306 kka2_1:4_A79Y,kka2_1:4_79,Kka2,kka2_1:4,P00552,1.01306,NO,79,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.368,-4.411,2.043,,0.563,.,B,0.46,-0.43,2.291,,71.59,HHH,-1.752,0.168804,0.00664821,1.01306 beta-lactamase_625_A268M,beta-lactamase_625_268,TEM-1,beta-lactamase_625,P62593,1.01307,NO,268,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.023,-2.456,0.433,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.213352,0.0102525,1.01307 beta-lactamase_625_L218M,beta-lactamase_625_218,TEM-1,beta-lactamase_625,P62593,1.01307,NO,218,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.391,-4.267,2.876,,,I,b,0.55,-0.53,17.202,17.202,74.48,OHH,-1.58867,0.213352,0.00618274,1.01307 beta-lactamase_625_P250K,beta-lactamase_625_250,TEM-1,beta-lactamase_625,P62593,1.01307,NO,250,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.213352,0.00550899,1.01307 beta-lactamase_A225T,beta-lactamase_225,TEM-1,beta-lactamase,P62593,1.01307,NO,225,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.845,-2.966,1.121,6.5181,1,T,B,0.58,-0.38,4.077,,74.48,OHO,-1.39967,0.221079,0.00465057,1.01307 beta-lactamase_39_L28N,beta-lactamase_39_28,TEM-1,beta-lactamase_39,P62593,1.01308,NO,28,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.579,-4.056,2.477,,0.277,H,A,0.55,-0.16,3.262,,93.01,PHH,-2.11333,0.0495842,0.00359321,1.01308 beta-lactamase_625_Q204S,beta-lactamase_625_204,TEM-1,beta-lactamase_625,P62593,1.01308,NO,204,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-1.382,-3.344,1.962,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.213352,0.00364106,1.01308 beta-lactamase_625_R239H,beta-lactamase_625_239,TEM-1,beta-lactamase_625,P62593,1.01308,NO,239,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.213352,0.00213852,1.01308 beta-lactamase_2500_D36N,beta-lactamase_2500_36,TEM-1,beta-lactamase_2500,P62593,1.01309,NO,36,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.732,-3.002,0.27,,0.555,H,A,0.75,1.17,2.26,,77.62,AAP,-1.91167,0.361275,0.00476483,1.01309 beta-lactamase_39_R59Q,beta-lactamase_39_59,TEM-1,beta-lactamase_39,P62593,1.01309,NO,59,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.345,-2.612,1.267,,0.329,S,L,1.2,-0.09,1.806,,73.08,HBO,-2.24267,0.0495842,0.00318082,1.01309 kka2_1:2_P12L,kka2_1:2_12,Kka2,kka2_1:2,P00552,1.01309,NO,12,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.853,-3.533,2.68,,,.,B,0.52,1.25,0.261,,48.11,POH,-1.80767,0.295029,0.00500011,1.01309 beta-lactamase_156_T138W,beta-lactamase_156_138,TEM-1,beta-lactamase_156,P62593,1.01312,NO,138,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.506,-5.551,3.045,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.111618,0.00487868,1.01312 kka2_1:2_L184Q,kka2_1:2_184,Kka2,kka2_1:2,P00552,1.01312,NO,184,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.496,-4.197,2.701,,0.489,E,B,0.55,-0.06,14.044,14.044,63.26,AHH,-1.24833,0.295029,0.00518742,1.01312 gb1_K239V,gb1_239,gb1,gb1,P06654,1.01313,NO,239,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-3.043,-3.446,0.403,,,,,,,1.326,,45.54,HBO,-2.31467,0.177985,0.00207004,1.01313 beta-lactamase_156_T138P,beta-lactamase_156_138,TEM-1,beta-lactamase_156,P62593,1.01314,NO,138,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.506,-3.038,0.532,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.111618,0.00487868,1.01314 beta-lactamase_2500_V29D,beta-lactamase_2500_29,TEM-1,beta-lactamase_2500,P62593,1.01314,NO,29,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-2.856,-2.298,-0.558,,0.733,H,A,0.44,-0.78,1.931,,93.01,HHB,-2.24733,0.361275,0.00318969,1.01314 beta-lactamase_625_S283Q,beta-lactamase_625_283,TEM-1,beta-lactamase_625,P62593,1.01314,NO,283,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.213352,0.0429138,1.01314 kka2_1:8_L94I,kka2_1:8_94,Kka2,kka2_1:8,P00552,1.01314,NO,94,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.618,-2.284,0.666,,0.058,E,B,1.59,-0.52,2.197,,56.06,HHO,-1.612,0.100394,0.00520888,1.01314 kka2_1:8_L94I,kka2_1:8_94,Kka2,kka2_1:8,P00552,1.01314,NO,94,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.618,-2.284,0.666,,0.058,E,B,1.59,-0.52,2.197,,56.06,HHO,-1.612,0.100394,0.00520888,1.01314 beta-lactamase_156_P217V,beta-lactamase_156_217,TEM-1,beta-lactamase_156,P62593,1.01315,NO,217,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-2.062,-3.65,1.588,,0.496,I,A,0.52,-0.33,2.303,,74.48,OOH,-1.64333,0.111618,0.00463211,1.01315 beta-lactamase_156_T147I,beta-lactamase_156_147,TEM-1,beta-lactamase_156,P62593,1.01315,NO,147,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.149,-2.792,1.643,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.111618,0.00226017,1.01315 beta-lactamase_625_R118A,beta-lactamase_625_118,TEM-1,beta-lactamase_625,P62593,1.01315,NO,118,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.413,-1.798,-0.615,,0.457,H,A,1.2,1.39,2.144,,77.62,HBA,-1.785,0.213352,0.00538794,1.01315 beta-lactamase_156_I285E,beta-lactamase_156_285,TEM-1,beta-lactamase_156,P62593,1.01316,NO,285,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.111618,0.101555,1.01316 beta-lactamase_156_L135M,beta-lactamase_156_135,TEM-1,beta-lactamase_156,P62593,1.01317,NO,135,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.002,-2.838,1.836,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.111618,0.00244423,1.01317 beta-lactamase_625_T112A,beta-lactamase_625_112,TEM-1,beta-lactamase_625,P62593,1.01317,NO,112,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.186,-1.933,-0.253,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.213352,0.00531334,1.01317 beta-lactamase_39_S241G,beta-lactamase_39_241,TEM-1,beta-lactamase_39,P62593,1.01318,NO,241,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.0495842,0.00452736,1.01318 beta-lactamase_625_G226D,beta-lactamase_625_226,TEM-1,beta-lactamase_625,P62593,1.01318,NO,226,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.461,-1.914,0.453,,0.701,T,l,0.29,-0.25,3.199,,74.48,HOH,-1.42933,0.213352,0.00665294,1.01318 beta-lactamase_G234G,beta-lactamase_234,TEM-1,beta-lactamase,P62593,1.01318,NO,234,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.62,-0.62,,4.24221,0.023,E,B,0.46,-0.86,,,,POH,-1.25733,0.221079,0.000889577,1.01318 beta-lactamase_S254T,beta-lactamase_254,TEM-1,beta-lactamase,P62593,1.01318,NO,254,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.126,-2.692,0.566,5.49575,0.312,,a,0.25,-0.48,24.91,24.91,69.58,OPB,-2.215,0.221079,0.00369,1.01318 beta-lactamase_156_A225S,beta-lactamase_156_225,TEM-1,beta-lactamase_156,P62593,1.01319,NO,225,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.845,-2.863,1.018,,1,T,B,0.46,-0.38,11.722,11.722,74.48,OHO,-1.39967,0.111618,0.00465057,1.01319 beta-lactamase_156_G194Y,beta-lactamase_156_194,TEM-1,beta-lactamase_156,P62593,1.01319,NO,194,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.396,-4.427,3.031,,0.276,S,b,0.29,0.36,1.346,,67.83,POA,-1.832,0.111618,0.00392163,1.01319 beta-lactamase_39_Q88W,beta-lactamase_39_88,TEM-1,beta-lactamase_39,P62593,1.01319,NO,88,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.086,-5.502,3.416,,0.807,,B,0.64,2.03,11.108,11.108,77.62,APH,-1.53433,0.0495842,0.00504167,1.01319 beta-lactamase_39_T178L,beta-lactamase_39_178,TEM-1,beta-lactamase_39,P62593,1.01319,NO,178,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-0.791,-3.133,2.342,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.0495842,0.000684366,1.01319 beta-lactamase_0_I245H,beta-lactamase_0_245,TEM-1,beta-lactamase_0,P62593,1.0132,NO,245,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.0500837,0.00391032,1.0132 beta-lactamase_156_A34V,beta-lactamase_156_34,TEM-1,beta-lactamase_156,P62593,1.0132,NO,34,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.059,-2.227,0.168,,,H,A,0.46,-0.54,3.614,,73.78,AHA,-1.74967,0.111618,0.00407913,1.0132 beta-lactamase_625_A215T,beta-lactamase_625_215,TEM-1,beta-lactamase_625,P62593,1.0132,NO,215,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.503,-2.291,0.788,,,,a,0.46,-0.93,3.583,,74.48,HHO,-1.42633,0.213352,0.00544007,1.0132 beta-lactamase_156_G234M,beta-lactamase_156_234,TEM-1,beta-lactamase_156,P62593,1.01321,NO,234,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.62,-4.93,4.31,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.111618,0.000889577,1.01321 beta-lactamase_156_R273P,beta-lactamase_156_273,TEM-1,beta-lactamase_156,P62593,1.01321,NO,273,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.314,-2.669,0.355,,0.564,H,A,1.2,1.57,20.248,20.248,73.78,ABP,-1.841,0.111618,0.0077952,1.01321 beta-lactamase_2500_H151E,beta-lactamase_2500_151,TEM-1,beta-lactamase_2500,P62593,1.01321,NO,151,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-2.96,-3.258,0.298,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.361275,0.00216946,1.01321 beta-lactamase_39_F64M,beta-lactamase_39_64,TEM-1,beta-lactamase_39,P62593,1.01321,NO,64,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-0.841,-4.255,3.414,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.0495842,0.000947691,1.01321 beta-lactamase_39_K190Q,beta-lactamase_39_190,TEM-1,beta-lactamase_39,P62593,1.01321,NO,190,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.994,-2.883,0.889,,0.371,H,A,2.34,0.16,1.513,,77.62,BBH,-1.64167,0.0495842,0.00574527,1.01321 beta-lactamase_625_P181A,beta-lactamase_625_181,TEM-1,beta-lactamase_625,P62593,1.01321,NO,181,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.813,-2.357,1.544,,,H,A,0.52,-1.14,1.797,,61.54,HOH,-1.795,0.213352,0.000703122,1.01321 beta-lactamase_0_R202S,beta-lactamase_0_202,TEM-1,beta-lactamase_0,P62593,1.01322,NO,202,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.292,-2.609,1.317,,0.188,H,A,1.2,0.62,7.016,,77.62,PBP,-1.54767,0.0500837,0.00321899,1.01322 beta-lactamase_39_R220L,beta-lactamase_39_220,TEM-1,beta-lactamase_39,P62593,1.01322,NO,220,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-0.942,-3.356,2.414,,0.295,I,A,1.2,-0.76,1.596,,74.48,HBP,-1.33633,0.0495842,0.00232421,1.01322 beta-lactamase_39_R242Q,beta-lactamase_39_242,TEM-1,beta-lactamase_39,P62593,1.01322,NO,242,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.0495842,0.00452879,1.01322 beta-lactamase_39_I140L,beta-lactamase_39_140,TEM-1,beta-lactamase_39,P62593,1.01323,NO,140,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.733,-1.622,-0.111,,0.128,H,A,0.48,0.41,1.16,,73.08,PHO,-1.48733,0.0495842,0.00597777,1.01323 beta-lactamase_156_V106F,beta-lactamase_156_106,TEM-1,beta-lactamase_156,P62593,1.01325,NO,106,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.218,-2.585,1.367,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.111618,0.00304168,1.01325 beta-lactamase_D207D,beta-lactamase_207,TEM-1,beta-lactamase,P62593,1.01326,NO,207,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.064,-2.064,,5.40404,0.409,H,A,0.23,0.12,1.975,,77.62,HAH,-1.77033,0.221079,0.00592942,1.01326 E1_Ubiquitin_A46N,E1_Ubiquitin_46,Uba1,E1_Ubiquitin,P0CG63,1.01326,NO,46,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.367,-3.649,2.282,,0.398,T,L,,-0.8,,,,HHO,-1.17167,0.18783,0.004233,1.01326 E1_Ubiquitin_F45Y,E1_Ubiquitin_45,Uba1,E1_Ubiquitin,P0CG63,1.01326,NO,45,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.149,-2.855,1.706,,0.26,E,B,,-0.99,,,,HHH,-1.316,0.18783,0.00193245,1.01326 E1_Ubiquitin_G47G,E1_Ubiquitin_47,Uba1,E1_Ubiquitin,P0CG63,1.01326,NO,47,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.999,-0.999,,,0.057,T,l,,-1.21,,,,HOB,-1.195,0.18783,0.00142261,1.01326 E1_Ubiquitin_L71R,E1_Ubiquitin_71,Uba1,E1_Ubiquitin,P0CG63,1.01326,NO,71,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.039,-3.75,2.711,,0.591,E,B,,-0.69,,,,BHB,-1.19433,0.18783,0.00148349,1.01326 E1_Ubiquitin_L71T,E1_Ubiquitin_71,Uba1,E1_Ubiquitin,P0CG63,1.01326,NO,71,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.039,-3.239,2.2,,0.591,E,B,,-0.69,,,,BHB,-1.19433,0.18783,0.00148349,1.01326 E1_Ubiquitin_L73N,E1_Ubiquitin_73,Uba1,E1_Ubiquitin,P0CG63,1.01326,NO,73,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.039,-3.94,2.901,,0.518,,B,1.3,1,,,,BHB,-1.175,0.18783,0.00111236,1.01326 E1_Ubiquitin_R74A,E1_Ubiquitin_74,Uba1,E1_Ubiquitin,P0CG63,1.01326,NO,74,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.302,-2.948,1.646,,0.838,T,A,,3.15,,,,HBO,-1.11333,0.18783,0.00180798,1.01326 E1_Ubiquitin_T68T,E1_Ubiquitin_68,Uba1,E1_Ubiquitin,P0CG63,1.01326,NO,68,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,,,,,,,,,,,,,OPH,-1.039,0.18783,0.00314321,1.01326 E1_Ubiquitin_T68Y,E1_Ubiquitin_68,Uba1,E1_Ubiquitin,P0CG63,1.01326,NO,68,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,,,,,,,,,,,,,OPH,-1.039,0.18783,0.00314321,1.01326 Pab1_E195K,Pab1_195,Pab1,Pab1,P04147,1.01326,NO,195,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.2,-2.877,1.677,,,,,,,,,,PAH,-1.72467,0.175299,0.000620107,1.01326 beta-lactamase_39_G141D,beta-lactamase_39_141,TEM-1,beta-lactamase_39,P62593,1.01327,NO,141,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.828,-2.284,1.456,,0.575,T,l,0.29,-0.28,0.722,,64.69,HOO,-1.08933,0.0495842,0.0012419,1.01327 beta-lactamase_39_S80R,beta-lactamase_39_80,TEM-1,beta-lactamase_39,P62593,1.01327,NO,80,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.029,-3.076,1.047,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.0495842,0.00565569,1.01327 kka2_1:1_A247S,kka2_1:1_247,Kka2,kka2_1:1,P00552,1.01327,NO,247,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.459,-2.453,-0.006,,1.01,S,A,0.46,0.65,7.731,7.731,92.05,HHH,-2.197,0.520039,0.0102428,1.01327 beta-lactamase_156_V117C,beta-lactamase_156_117,TEM-1,beta-lactamase_156,P62593,1.01328,NO,117,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.53,-4.787,3.257,,,H,A,0.44,-0.34,1.182,,65.03,PHB,-1.741,0.111618,0.00467906,1.01328 beta-lactamase_F149F,beta-lactamase_149,TEM-1,beta-lactamase,P62593,1.01328,NO,149,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.299,-1.299,,5.54789,0.195,H,A,1.1,0.11,1.863,,63.99,HHH,-1.46067,0.221079,0.00418462,1.01328 beta-lactamase_K252H,beta-lactamase_252,TEM-1,beta-lactamase,P62593,1.01328,NO,252,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.94,-2.939,0.999,5.56823,0.766,,B,1.82,1.16,21.796,21.796,67.83,OBO,-2.03333,0.221079,0.00575769,1.01328 beta-lactamase_Q4N,beta-lactamase_4,TEM-1,beta-lactamase,P62593,1.01328,NO,4,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,,-3.483,0.919,,,,,,,,,,HPB,,0.221079,0.00316562,1.01328 beta-lactamase_T112I,beta-lactamase_112,TEM-1,beta-lactamase,P62593,1.01328,NO,112,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.186,-3.949,1.763,6.47162,0.921,T,A,0.77,1.06,2.04,,73.78,HPA,-1.925,0.221079,0.00531334,1.01328 beta-lactamase_0_R63C,beta-lactamase_0_63,TEM-1,beta-lactamase_0,P62593,1.01329,NO,63,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-0.943,-5.05,4.107,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.0500837,0.00126938,1.01329 beta-lactamase_0_S80A,beta-lactamase_0_80,TEM-1,beta-lactamase_0,P62593,1.01329,NO,80,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.029,-1.631,-0.398,,0.192,H,A,0.27,0.46,12.403,12.403,77.62,HPB,-1.44567,0.0500837,0.00565569,1.01329 beta-lactamase_156_I45C,beta-lactamase_156_45,TEM-1,beta-lactamase_156,P62593,1.01329,NO,45,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-2.421,-4.903,2.482,,,E,B,0.48,-0.3,2.256,,77.62,HHA,-2.30267,0.111618,0.00452842,1.01329 beta-lactamase_39_K30M,beta-lactamase_39_30,TEM-1,beta-lactamase_39,P62593,1.01329,NO,30,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-2.307,-4.578,2.271,,0.142,H,A,2.34,-0.65,6.717,,93.01,HBH,-2.32833,0.0495842,0.00448593,1.01329 hsp90_Q582L,hsp90_582,hsp90,hsp90,P02829,1.01331,NO,582,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-3.278,-2.511,0,4.91603,0.453,S,B,,0.67,,,,OPH,-3.249,0.368192,0.000222939,1.01331 kka2_1:8_V185I,kka2_1:8_185,Kka2,kka2_1:8,P00552,1.01331,NO,185,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.045,-2.468,1.423,,0.058,E,B,1.48,-0.49,1.234,,46.97,HHH,-1.184,0.100394,0.00367031,1.01331 kka2_1:8_V185I,kka2_1:8_185,Kka2,kka2_1:8,P00552,1.01331,NO,185,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.045,-2.468,1.423,,0.058,E,B,1.48,-0.49,1.234,,46.97,HHH,-1.184,0.100394,0.00367031,1.01331 beta-lactamase_39_N274T,beta-lactamase_39_274,TEM-1,beta-lactamase_39,P62593,1.01332,NO,274,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.0495842,0.0110418,1.01332 PSD95pdz3_K355R,PSD95pdz3_355,PSD95pdz3,PSD95pdz3,P31016,1.01332,NO,355,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.416,-2.715,1.299,5.56865,,,,,17.2556,,,,BBO,-1.33533,0.0758425,0.00063703,1.01332 kka2_1:8_S54W,kka2_1:8_54,Kka2,kka2_1:8,P00552,1.01333,NO,54,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.471,-5.559,3.088,,0.408,S,b,0.77,1.01,13.679,13.679,71.59,HPO,-2.259,0.100394,0.00782867,1.01333 kka2_1:8_S54W,kka2_1:8_54,Kka2,kka2_1:8,P00552,1.01333,NO,54,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.471,-5.559,3.088,,0.408,S,b,0.77,1.01,13.679,13.679,71.59,HPO,-2.259,0.100394,0.00782867,1.01333 beta-lactamase_625_A222H,beta-lactamase_625_222,TEM-1,beta-lactamase_625,P62593,1.01334,NO,222,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.103,-2.705,0.602,,0.233,H,A,0.46,-0.25,1.448,,77.62,PHH,-1.63733,0.213352,0.00466094,1.01334 beta-lactamase_625_E145F,beta-lactamase_625_145,TEM-1,beta-lactamase_625,P62593,1.01334,NO,145,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.357,-4.373,2.016,,0.545,H,A,1.04,0.79,2.64,,77.62,BAH,-2.069,0.213352,0.00553285,1.01334 beta-lactamase_625_G236N,beta-lactamase_625_236,TEM-1,beta-lactamase_625,P62593,1.01334,NO,236,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.784,-3.509,2.725,,0.241,,b,0.29,-0.59,3.506,,64.69,HOO,-1.025,0.213352,0.00162372,1.01334 beta-lactamase_156_P181A,beta-lactamase_156_181,TEM-1,beta-lactamase_156,P62593,1.01335,NO,181,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.813,-2.357,1.544,,,H,A,0.52,-1.14,1.078,,61.54,HOH,-1.795,0.111618,0.000703122,1.01335 kka2_1:4_L184W,kka2_1:4_184,Kka2,kka2_1:4,P00552,1.01335,NO,184,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.496,-3.533,2.037,,0.489,E,B,1.59,-0.06,4.495,,63.26,AHH,-1.24833,0.168804,0.00518742,1.01335 beta-lactamase_156_V29G,beta-lactamase_156_29,TEM-1,beta-lactamase_156,P62593,1.01336,NO,29,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-2.856,-2.66,-0.196,,0.733,H,A,0.44,-0.78,3.685,,93.01,HHB,-2.24733,0.111618,0.00318969,1.01336 beta-lactamase_2500_H151M,beta-lactamase_2500_151,TEM-1,beta-lactamase_2500,P62593,1.01336,NO,151,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-2.96,-4.581,1.621,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.361275,0.00216946,1.01336 beta-lactamase_156_E35N,beta-lactamase_156_35,TEM-1,beta-lactamase_156,P62593,1.01337,NO,35,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-0.869,-3.445,2.576,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.111618,0.00174441,1.01337 beta-lactamase_156_S51F,beta-lactamase_156_51,TEM-1,beta-lactamase_156,P62593,1.01337,NO,51,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.526,-4.284,2.758,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.111618,0.00504821,1.01337 beta-lactamase_625_W208F,beta-lactamase_625_208,TEM-1,beta-lactamase_625,P62593,1.01337,NO,208,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-0.818,-3.392,2.574,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.213352,0.00126609,1.01337 kka2_1:4_R143G,kka2_1:4_143,Kka2,kka2_1:4,P00552,1.01337,NO,143,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.525,-3.627,1.102,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.168804,0.00662247,1.01337 WW_domain_A175R,WW_domain_175,Yap65,WW_domain,P46937,1.01337,NO,175,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.631,-3.746,2.115,6.69537,,,,,,6.257,,83.93,OHO,-1.30033,0.153962,0.00326874,1.01337 beta-lactamase_156_T138A,beta-lactamase_156_138,TEM-1,beta-lactamase_156,P62593,1.01338,NO,138,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.506,-2.248,-0.258,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.111618,0.00487868,1.01338 kka2_1:1_A79S,kka2_1:1_79,Kka2,kka2_1:1,P00552,1.01338,NO,79,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.368,-2.87,0.502,,0.563,.,B,0.46,-0.43,7.792,7.792,71.59,HHH,-1.752,0.520039,0.00664821,1.01338 beta-lactamase_156_R275S,beta-lactamase_156_275,TEM-1,beta-lactamase_156,P62593,1.0134,NO,275,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.111618,0.0141984,1.0134 beta-lactamase_156_T27H,beta-lactamase_156_27,TEM-1,beta-lactamase_156,P62593,1.0134,NO,27,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.905,-4.62,2.715,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.111618,0.00306559,1.0134 beta-lactamase_39_H151L,beta-lactamase_39_151,TEM-1,beta-lactamase_39,P62593,1.0134,NO,151,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-2.96,-3.494,0.534,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.0495842,0.00216946,1.0134 beta-lactamase_625_A84W,beta-lactamase_625_84,TEM-1,beta-lactamase_625,P62593,1.0134,NO,84,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.651,-5.52,3.869,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.213352,0.00503822,1.0134 beta-lactamase_T186R,beta-lactamase_186,TEM-1,beta-lactamase,P62593,1.0134,NO,186,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.522,-2.819,0.297,5.07364,0.396,H,A,0.3,-0.28,2.144,,77.62,HPP,-1.77633,0.221079,0.00485034,1.0134 beta-lactamase_39_M127R,beta-lactamase_39_127,TEM-1,beta-lactamase_39,P62593,1.01341,NO,127,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-2.251,-2.722,0.471,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.0495842,0.00437927,1.01341 beta-lactamase_156_L135V,beta-lactamase_156_135,TEM-1,beta-lactamase_156,P62593,1.01342,NO,135,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.002,-2.8,1.798,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.111618,0.00244423,1.01342 beta-lactamase_625_Q97E,beta-lactamase_625_97,TEM-1,beta-lactamase_625,P62593,1.01342,NO,97,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.072,-2.167,0.095,,0.823,G,A,0.64,2.42,16.954,16.954,77.62,PPP,-2.43833,0.213352,0.0045116,1.01342 gb1_I232K,gb1_232,gb1,gb1,P06654,1.01342,NO,232,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-2.175,-3.559,1.384,,,,,,,0.766,,44.87,HHH,-2.152,0.177985,0.00580459,1.01342 beta-lactamase_D207Y,beta-lactamase_207,TEM-1,beta-lactamase,P62593,1.01343,NO,207,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.064,-4.317,2.253,5.40404,0.409,H,A,0.23,0.12,1.975,,77.62,HAH,-1.77033,0.221079,0.00592942,1.01343 beta-lactamase_39_S256T,beta-lactamase_39_256,TEM-1,beta-lactamase_39,P62593,1.01344,NO,256,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.0495842,0.00710634,1.01344 beta-lactamase_A170A,beta-lactamase_170,TEM-1,beta-lactamase,P62593,1.01344,NO,170,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.237,-1.237,,5.19261,0.126,,L,2.34,-0.35,2.427,,64.69,AHH,-1.63267,0.221079,0.00431903,1.01344 beta-lactamase_156_S241Q,beta-lactamase_156_241,TEM-1,beta-lactamase_156,P62593,1.01345,NO,241,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.111618,0.00452736,1.01345 beta-lactamase_625_R202H,beta-lactamase_625_202,TEM-1,beta-lactamase_625,P62593,1.01345,NO,202,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.292,-4.365,3.073,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.213352,0.00321899,1.01345 beta-lactamase_156_M184Y,beta-lactamase_156_184,TEM-1,beta-lactamase_156,P62593,1.01346,NO,184,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.593,-4.027,2.434,,,H,A,0.55,-0.87,1.671,,62.94,HHH,-1.41,0.111618,0.00356019,1.01346 beta-lactamase_625_A84D,beta-lactamase_625_84,TEM-1,beta-lactamase_625,P62593,1.01346,NO,84,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.651,-2.92,1.269,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.213352,0.00503822,1.01346 beta-lactamase_625_T138S,beta-lactamase_625_138,TEM-1,beta-lactamase_625,P62593,1.01346,NO,138,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.506,-2.455,-0.051,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.213352,0.00487868,1.01346 beta-lactamase_156_I93F,beta-lactamase_156_93,TEM-1,beta-lactamase_156,P62593,1.01347,NO,93,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.401,-3.88,2.479,,0.128,E,B,0.48,0.44,1.524,,67.83,BHB,-1.873,0.111618,0.00527066,1.01347 beta-lactamase_2500_L248I,beta-lactamase_2500_248,TEM-1,beta-lactamase_2500,P62593,1.01347,NO,248,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.361275,0.00428493,1.01347 beta-lactamase_625_T263H,beta-lactamase_625_263,TEM-1,beta-lactamase_625,P62593,1.01347,NO,263,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.213352,0.0110582,1.01347 PSD95pdz3_A378R,PSD95pdz3_378,PSD95pdz3,PSD95pdz3,P31016,1.01347,NO,378,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.307,-3.39,2.083,4.86582,,,,,14.576,,,,HHH,-1.509,0.0758425,0.000313169,1.01347 beta-lactamase_0_S104P,beta-lactamase_0_104,TEM-1,beta-lactamase_0,P62593,1.01348,NO,104,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.015,-3.751,2.736,,0.04,,b,0.27,0.57,1.148,,63.29,HPO,-1.05267,0.0500837,0.00218083,1.01348 beta-lactamase_625_Q97T,beta-lactamase_625_97,TEM-1,beta-lactamase_625,P62593,1.01348,NO,97,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.072,-2.713,0.641,,0.823,G,A,0.64,2.42,16.954,16.954,77.62,PPP,-2.43833,0.213352,0.0045116,1.01348 beta-lactamase_625_G90F,beta-lactamase_625_90,TEM-1,beta-lactamase_625,P62593,1.01349,NO,90,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-2.091,-4.407,2.316,,0.598,T,A,0.29,0.32,0.319,,77.62,HOB,-1.52633,0.213352,0.00490273,1.01349 kka2_1:4_P167T,kka2_1:4_167,Kka2,kka2_1:4,P00552,1.01349,NO,167,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-2.403,-2.47,0.067,,0.18,H,A,0.52,0.75,3.6,,64.39,HOH,-2.26633,0.168804,0.00543203,1.01349 beta-lactamase_156_L160M,beta-lactamase_156_160,TEM-1,beta-lactamase_156,P62593,1.0135,NO,160,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.977,-3.902,2.925,,0.022,,B,0.55,-0.6,1.095,,44.41,BHA,-0.936,0.111618,0.00193775,1.0135 kka2_1:2_A108E,kka2_1:2_108,Kka2,kka2_1:2,P00552,1.0135,NO,108,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.061,-2.517,0.456,,0.243,.,B,0.46,-1.34,2.462,,71.59,HHO,-1.57033,0.295029,0.00751209,1.0135 beta-lactamase_39_P25I,beta-lactamase_39_25,TEM-1,beta-lactamase_39,P62593,1.01351,NO,25,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.526,-4.029,2.503,,0.624,H,A,0.52,0.14,1.157,,73.08,BOA,-2.15367,0.0495842,0.00347571,1.01351 beta-lactamase_N98K,beta-lactamase_98,TEM-1,beta-lactamase,P62593,1.01351,NO,98,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-2.973,-2.653,-0.32,6.59973,0.963,G,A,1.07,1.35,1.332,,77.62,PPA,-2.07867,0.221079,0.00505389,1.01351 Pab1_E195H,Pab1_195,Pab1,Pab1,P04147,1.01351,NO,195,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.2,-4.1,2.9,,,,,,,,,,PAH,-1.72467,0.175299,0.000620107,1.01351 beta-lactamase_39_A34Y,beta-lactamase_39_34,TEM-1,beta-lactamase_39,P62593,1.01354,NO,34,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.059,-4.077,2.018,,,H,A,0.46,-0.54,13.292,13.292,73.78,AHA,-1.74967,0.0495842,0.00407913,1.01354 beta-lactamase_39_L55H,beta-lactamase_39_55,TEM-1,beta-lactamase_39,P62593,1.01354,NO,55,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.86,-4.855,2.995,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.0495842,0.00403741,1.01354 beta-lactamase_625_T138A,beta-lactamase_625_138,TEM-1,beta-lactamase_625,P62593,1.01354,NO,138,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.506,-2.248,-0.258,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.213352,0.00487868,1.01354 hsp90_Q582K,hsp90_582,hsp90,hsp90,P02829,1.01354,NO,582,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-3.278,-2.835,0,4.91603,0.453,S,B,,0.67,,,,OPH,-3.249,0.368192,0.000222939,1.01354 PSD95pdz3_G319H,PSD95pdz3_319,PSD95pdz3,PSD95pdz3,P31016,1.01354,NO,319,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.008,-4.362,3.354,4.95387,,,,,18.8725,,,,BOP,-1.36967,0.0758425,0.00109317,1.01354 beta-lactamase_156_E195S,beta-lactamase_156_195,TEM-1,beta-lactamase_156,P62593,1.01355,NO,195,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.186,-2.512,0.326,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.111618,0.00496565,1.01355 beta-lactamase_156_I285K,beta-lactamase_156_285,TEM-1,beta-lactamase_156,P62593,1.01355,NO,285,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.111618,0.101555,1.01355 beta-lactamase_2500_P25H,beta-lactamase_2500_25,TEM-1,beta-lactamase_2500,P62593,1.01355,NO,25,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.526,-4.604,3.078,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.361275,0.00347571,1.01355 kka2_1:4_G88D,kka2_1:4_88,Kka2,kka2_1:4,P00552,1.01355,NO,88,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.689,-2.184,0.495,,0.54,S,l,0.29,1.51,7.899,,65.53,HOB,-1.718,0.168804,0.00685559,1.01355 beta-lactamase_156_K109N,beta-lactamase_156_109,TEM-1,beta-lactamase_156,P62593,1.01356,NO,109,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.734,-2.767,1.033,,0.787,G,A,2.34,2.21,6.031,,72.73,ABB,-1.63333,0.111618,0.00462493,1.01356 beta-lactamase_625_T186F,beta-lactamase_625_186,TEM-1,beta-lactamase_625,P62593,1.01356,NO,186,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.522,-4.342,1.82,,0.396,H,A,0.22,-0.28,0.515,,77.62,HPP,-1.77633,0.213352,0.00485034,1.01356 beta-lactamase_K190N,beta-lactamase_190,TEM-1,beta-lactamase,P62593,1.01358,NO,190,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.994,-2.601,0.607,5.49163,0.371,H,A,1.82,0.16,29.753,29.753,77.62,BBH,-1.64167,0.221079,0.00574527,1.01358 beta-lactamase_156_F70Q,beta-lactamase_156_70,TEM-1,beta-lactamase_156,P62593,1.01359,NO,70,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.169,-4.201,3.032,,,H,A,0.58,-1.34,1.918,,63.99,PHB,-0.980667,0.111618,0.00193499,1.01359 beta-lactamase_2500_P25V,beta-lactamase_2500_25,TEM-1,beta-lactamase_2500,P62593,1.01359,NO,25,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.526,-3.565,2.039,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.361275,0.00347571,1.01359 beta-lactamase_156_L197W,beta-lactamase_156_197,TEM-1,beta-lactamase_156,P62593,1.0136,NO,197,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.853,-5.146,4.293,,0.007,S,B,0.55,0.33,1.58,,60.14,HHP,-1.833,0.111618,0.00144602,1.0136 beta-lactamase_39_D174P,beta-lactamase_39_174,TEM-1,beta-lactamase_39,P62593,1.0136,NO,174,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.738,-3.655,2.917,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.0495842,0.00125633,1.0136 beta-lactamase_L188L,beta-lactamase_188,TEM-1,beta-lactamase,P62593,1.0136,NO,188,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.166,-1.166,,5.55434,,H,A,1.07,-0.3,1.574,,60.14,PHB,-1.47033,0.221079,0.00295687,1.0136 beta-lactamase_625_E166Y,beta-lactamase_625_166,TEM-1,beta-lactamase_625,P62593,1.01361,NO,166,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.756,-4.36,2.604,,0.508,G,A,1.04,1.05,2.124,,73.08,OAH,-1.42233,0.213352,0.00512989,1.01361 beta-lactamase_0_A182Y,beta-lactamase_0_182,TEM-1,beta-lactamase_0,P62593,1.01362,NO,182,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.777,-4.299,2.522,,0.136,H,A,0.46,-0.66,10.765,10.765,93.01,OHH,-1.27367,0.0500837,0.00559099,1.01362 beta-lactamase_39_T186S,beta-lactamase_39_186,TEM-1,beta-lactamase_39,P62593,1.01362,NO,186,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.522,-2.471,-0.051,,0.396,H,A,0.22,-0.28,0.515,,77.62,HPP,-1.77633,0.0495842,0.00485034,1.01362 beta-lactamase_625_E61A,beta-lactamase_625_61,TEM-1,beta-lactamase_625,P62593,1.01362,NO,61,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.115,-2.668,0.553,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.213352,0.00440955,1.01362 beta-lactamase_625_I54Q,beta-lactamase_625_54,TEM-1,beta-lactamase_625,P62593,1.01362,NO,54,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-2.838,-2.926,0.088,,0.669,E,B,0.48,-0.14,3.946,,73.78,BHH,-2.337,0.213352,0.00403589,1.01362 beta-lactamase_156_K190L,beta-lactamase_156_190,TEM-1,beta-lactamase_156,P62593,1.01363,NO,190,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.994,-3.527,1.533,,0.371,H,A,2.34,0.16,1.513,,77.62,BBH,-1.64167,0.111618,0.00574527,1.01363 beta-lactamase_156_L196I,beta-lactamase_156_196,TEM-1,beta-lactamase_156,P62593,1.01363,NO,196,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-2.478,-2.648,0.17,,0.518,S,A,0.55,1.35,7.897,,77.62,AHH,-1.839,0.111618,0.00512144,1.01363 beta-lactamase_2500_E61M,beta-lactamase_2500_61,TEM-1,beta-lactamase_2500,P62593,1.01364,NO,61,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.115,-4.881,2.766,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.361275,0.00440955,1.01364 beta-lactamase_39_F70N,beta-lactamase_39_70,TEM-1,beta-lactamase_39,P62593,1.01364,NO,70,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.169,-4.034,2.865,,,H,A,0.58,-1.34,1.14,,63.99,PHB,-0.980667,0.0495842,0.00193499,1.01364 beta-lactamase_39_V72T,beta-lactamase_39_72,TEM-1,beta-lactamase_39,P62593,1.01364,NO,72,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.658,-2.757,1.099,,,H,A,0.44,-1.03,1.92,,65.73,BHH,-1.32167,0.0495842,0.00501194,1.01364 beta-lactamase_39_P105L,beta-lactamase_39_105,TEM-1,beta-lactamase_39,P62593,1.01366,NO,105,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.813,-3.581,2.768,,0.226,T,A,0.52,0.8,1.222,,63.29,POH,-1.01533,0.0495842,0.0011981,1.01366 PSD95pdz3_Q391T,PSD95pdz3_391,PSD95pdz3,PSD95pdz3,P31016,1.01366,NO,391,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-1.699,-3.103,1.404,5.50275,,,,,12.6589,,,,HPH,-1.481,0.0758425,0.000990786,1.01366 beta-lactamase_156_R239D,beta-lactamase_156_239,TEM-1,beta-lactamase_156,P62593,1.01367,NO,239,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.111618,0.00213852,1.01367 beta-lactamase_156_V157Q,beta-lactamase_156_157,TEM-1,beta-lactamase_156,P62593,1.01367,NO,157,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.751,-4.045,2.294,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.111618,0.00506849,1.01367 beta-lactamase_39_Q88D,beta-lactamase_39_88,TEM-1,beta-lactamase_39,P62593,1.01367,NO,88,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.086,-2.035,-0.051,,0.807,,B,0.64,2.03,11.108,11.108,77.62,APH,-1.53433,0.0495842,0.00504167,1.01367 beta-lactamase_39_C121V,beta-lactamase_39_121,TEM-1,beta-lactamase_39,P62593,1.01368,NO,121,C,V,CV,Special,Hydrophobic,5.07,5.60847,0.538465,192,121,117,-4,108.5,140,31.5,-0.953,-3.371,2.418,,,H,A,0.46,-0.81,7.644,,63.29,HOP,-1.46767,0.0495842,0.000744322,1.01368 beta-lactamase_625_L205I,beta-lactamase_625_205,TEM-1,beta-lactamase_625,P62593,1.01368,NO,205,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.922,-2.97,2.048,,,H,A,0.55,-0.46,3.782,,42.31,PHH,-1.57767,0.213352,0.00255802,1.01368 beta-lactamase_E175E,beta-lactamase_175,TEM-1,beta-lactamase,P62593,1.01368,NO,175,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.336,-2.336,,6.0311,0.551,,A,0.75,1.05,5.316,,77.62,AAB,-1.31233,0.221079,0.00482205,1.01368 beta-lactamase_0_D99I,beta-lactamase_0_99,TEM-1,beta-lactamase_0,P62593,1.01369,NO,99,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.191,-3.979,2.788,,0.402,G,A,0.75,0.36,0.374,,64.69,PAH,-1.794,0.0500837,0.00305446,1.01369 beta-lactamase_156_V157H,beta-lactamase_156_157,TEM-1,beta-lactamase_156,P62593,1.01369,NO,157,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.751,-3.319,1.568,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.111618,0.00506849,1.01369 beta-lactamase_156_A170L,beta-lactamase_156_170,TEM-1,beta-lactamase_156,P62593,1.0137,NO,170,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.237,-3.289,2.052,,0.126,,L,0.46,-0.35,3.7,,64.69,AHH,-1.63267,0.111618,0.00431903,1.0137 beta-lactamase_39_L49P,beta-lactamase_39_49,TEM-1,beta-lactamase_39,P62593,1.0137,NO,49,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.897,-2.49,0.593,,0.131,T,A,0.55,0.04,13.838,13.838,64.69,AHP,-1.99233,0.0495842,0.00401477,1.0137 beta-lactamase_2500_R118H,beta-lactamase_2500_118,TEM-1,beta-lactamase_2500,P62593,1.01371,NO,118,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.413,-4.71,2.297,,0.457,H,A,1.2,1.39,2.144,,77.62,HBA,-1.785,0.361275,0.00538794,1.01371 beta-lactamase_39_T131H,beta-lactamase_39_131,TEM-1,beta-lactamase_39,P62593,1.01371,NO,131,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.328,-4.721,3.393,,,H,A,0.22,-0.69,3.306,,67.48,PPH,-1.00867,0.0495842,0.00345886,1.01371 beta-lactamase_625_P105K,beta-lactamase_625_105,TEM-1,beta-lactamase_625,P62593,1.01371,NO,105,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.813,-3.454,2.641,,0.226,T,A,0.52,0.8,1.154,,63.29,POH,-1.01533,0.213352,0.0011981,1.01371 kka2_1:2_R202T,kka2_1:2_202,Kka2,kka2_1:2,P00552,1.01371,NO,202,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.761,-3.676,1.915,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.295029,0.00696498,1.01371 beta-lactamase_39_A182H,beta-lactamase_39_182,TEM-1,beta-lactamase_39,P62593,1.01372,NO,182,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.777,-3.358,1.581,,0.136,H,A,0.46,-0.66,2.598,,93.01,OHH,-1.27367,0.0495842,0.00559099,1.01372 beta-lactamase_625_P60F,beta-lactamase_625_60,TEM-1,beta-lactamase_625,P62593,1.01372,NO,60,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-2.469,-4.292,1.823,,0.256,T,A,0.52,-0.56,3.653,,77.62,BOA,-1.97633,0.213352,0.00521318,1.01372 beta-lactamase_D207E,beta-lactamase_207,TEM-1,beta-lactamase,P62593,1.01372,NO,207,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.064,-2.615,0.551,5.40404,0.409,H,A,0.23,0.12,1.975,,77.62,HAH,-1.77033,0.221079,0.00592942,1.01372 beta-lactamase_D36C,beta-lactamase_36,TEM-1,beta-lactamase,P62593,1.01372,NO,36,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.732,-5.131,2.399,5.39764,0.555,H,A,0.11,1.17,13.689,13.689,77.62,AAP,-1.91167,0.221079,0.00476483,1.01372 beta-lactamase_I3K,beta-lactamase_3,TEM-1,beta-lactamase,P62593,1.01372,NO,3,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-2.143,-2.447,0.304,,,,,,,3.946,,93.01,PHP,-2.21633,0.221079,0.00349304,1.01372 beta-lactamase_Q4E,beta-lactamase_4,TEM-1,beta-lactamase,P62593,1.01372,NO,4,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,,-2.358,-0.206,,,,,,,,,,HPB,,0.221079,0.00316562,1.01372 beta-lactamase_T193M,beta-lactamase_193,TEM-1,beta-lactamase,P62593,1.01372,NO,193,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.914,-4.362,2.448,5.67952,0.439,H,a,0.3,0.33,1.863,,63.99,HPO,-1.52133,0.221079,0.00482669,1.01372 PSD95pdz3_K380M,PSD95pdz3_380,PSD95pdz3,PSD95pdz3,P31016,1.01372,NO,380,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.416,-4.162,2.746,5.87979,,,,,19.6722,,,,HBP,-1.391,0.0758425,0.000281399,1.01372 beta-lactamase_625_S51N,beta-lactamase_625_51,TEM-1,beta-lactamase_625,P62593,1.01375,NO,51,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.526,-2.556,1.03,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.213352,0.00504821,1.01375 beta-lactamase_0_C75H,beta-lactamase_0_75,TEM-1,beta-lactamase_0,P62593,1.01376,NO,75,C,H,CH,Special,PositiveCharge,5.07,7.59,2.52,174,121,155,34,108.5,153.2,44.7,-1.245,-4.871,3.626,,,H,A,0.46,-0.87,2.256,,50,HOO,-1.24333,0.0500837,0.0034616,1.01376 beta-lactamase_39_E279S,beta-lactamase_39_279,TEM-1,beta-lactamase_39,P62593,1.01376,NO,279,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.0495842,0.0192826,1.01376 beta-lactamase_39_T178H,beta-lactamase_39_178,TEM-1,beta-lactamase_39,P62593,1.01376,NO,178,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-0.791,-4.68,3.889,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.0495842,0.000684366,1.01376 beta-lactamase_E145A,beta-lactamase_145,TEM-1,beta-lactamase,P62593,1.01376,NO,145,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.357,-1.901,-0.456,5.38104,0.545,H,A,0.52,0.79,2.124,,77.62,BAH,-2.069,0.221079,0.00553285,1.01376 PSD95pdz3_S371A,PSD95pdz3_371,PSD95pdz3,PSD95pdz3,P31016,1.01376,NO,371,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.86,-2.533,0.673,5.19744,,,,,17.1117,3.854,,87.71,HPB,-1.598,0.0758425,0.000847873,1.01376 beta-lactamase_Q86I,beta-lactamase_86,TEM-1,beta-lactamase,P62593,1.01377,NO,86,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.4,-3.877,1.477,5.39897,0.696,S,A,0.12,2.38,2.105,,77.62,OPA,-1.61067,0.221079,0.00450027,1.01377 beta-lactamase_0_L191Y,beta-lactamase_0_191,TEM-1,beta-lactamase_0,P62593,1.01378,NO,191,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.087,-3.913,2.826,,,H,A,0.55,0.09,12.255,12.255,63.29,BHH,-1.445,0.0500837,0.00263549,1.01378 beta-lactamase_156_L74I,beta-lactamase_156_74,TEM-1,beta-lactamase_156,P62593,1.01379,NO,74,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.296,-2.577,1.281,,,H,A,0.55,-0.91,0.746,,50,HHO,-1.34933,0.111618,0.00493255,1.01379 beta-lactamase_2500_L248M,beta-lactamase_2500_248,TEM-1,beta-lactamase_2500,P62593,1.0138,NO,248,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.361275,0.00428493,1.0138 beta-lactamase_39_G226L,beta-lactamase_39_226,TEM-1,beta-lactamase_39,P62593,1.0138,NO,226,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.461,-3.765,2.304,,0.701,T,l,0.29,-0.25,23.034,23.034,74.48,HOH,-1.42933,0.0495842,0.00665294,1.0138 beta-lactamase_39_P224S,beta-lactamase_39_224,TEM-1,beta-lactamase_39,P62593,1.0138,NO,224,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.893,-2.58,1.687,,0.383,,B,0.52,-0.3,3.169,,74.48,HOH,-1.26433,0.0495842,0.00189564,1.0138 beta-lactamase_39_M66Q,beta-lactamase_39_66,TEM-1,beta-lactamase_39,P62593,1.01381,NO,66,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.362,-3.949,2.587,,0.013,,A,0.55,-0.7,1.319,,73.08,OHH,-1.49567,0.0495842,0.00412876,1.01381 beta-lactamase_625_E61I,beta-lactamase_625_61,TEM-1,beta-lactamase_625,P62593,1.01382,NO,61,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.115,-4.14,2.025,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.213352,0.00440955,1.01382 beta-lactamase_I3N,beta-lactamase_3,TEM-1,beta-lactamase,P62593,1.01382,NO,3,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-2.143,-3.866,1.723,,,,,,,3.946,,93.01,PHP,-2.21633,0.221079,0.00349304,1.01382 beta-lactamase_156_H110A,beta-lactamase_156_110,TEM-1,beta-lactamase_156,P62593,1.01383,NO,110,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-1.706,-3.353,1.647,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.111618,0.00441499,1.01383 beta-lactamase_39_V29H,beta-lactamase_39_29,TEM-1,beta-lactamase_39,P62593,1.01383,NO,29,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-2.856,-4.571,1.715,,0.733,H,A,0.44,-0.78,1.287,,93.01,HHB,-2.24733,0.0495842,0.00318969,1.01383 beta-lactamase_156_A200C,beta-lactamase_156_200,TEM-1,beta-lactamase_156,P62593,1.01384,NO,200,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.878,-5.005,3.127,,0.757,H,A,0.46,-0.19,16.368,16.368,77.62,HHP,-2.001,0.111618,0.0060056,1.01384 beta-lactamase_156_E108V,beta-lactamase_156_108,TEM-1,beta-lactamase_156,P62593,1.01384,NO,108,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.46,-3.706,2.246,,0.572,G,A,1.04,1.87,8.602,8.602,72.73,PAB,-1.437,0.111618,0.00413372,1.01384 beta-lactamase_156_E279L,beta-lactamase_156_279,TEM-1,beta-lactamase_156,P62593,1.01384,NO,279,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.111618,0.0192826,1.01384 beta-lactamase_2500_A182H,beta-lactamase_2500_182,TEM-1,beta-lactamase_2500,P62593,1.01385,NO,182,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.777,-3.358,1.581,,0.136,H,A,0.46,-0.66,2.032,,93.01,OHH,-1.27367,0.361275,0.00559099,1.01385 beta-lactamase_2500_V29A,beta-lactamase_2500_29,TEM-1,beta-lactamase_2500,P62593,1.01385,NO,29,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-2.856,-2.61,-0.246,,0.733,H,A,0.44,-0.78,1.931,,93.01,HHB,-2.24733,0.361275,0.00318969,1.01385 beta-lactamase_625_T112P,beta-lactamase_625_112,TEM-1,beta-lactamase_625,P62593,1.01385,NO,112,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.186,-3.939,1.753,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.213352,0.00531334,1.01385 beta-lactamase_156_L135Q,beta-lactamase_156_135,TEM-1,beta-lactamase_156,P62593,1.01386,NO,135,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.002,-4.162,3.16,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.111618,0.00244423,1.01386 beta-lactamase_D174D,beta-lactamase_174,TEM-1,beta-lactamase,P62593,1.01386,NO,174,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.738,-0.738,,5.44133,0.238,,B,1.22,-0.1,,,,PAA,-1.91233,0.221079,0.00125633,1.01386 beta-lactamase_0_A124S,beta-lactamase_0_124,TEM-1,beta-lactamase_0,P62593,1.01387,NO,124,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.181,-3.066,1.885,,,H,A,0.46,-0.9,1.876,,64.34,HHH,-1.152,0.0500837,0.00481399,1.01387 gb1_A246T,gb1_246,gb1,gb1,P06654,1.01387,NO,246,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.175,-2.932,1.757,,,,,,,,,,AHH,-1.87033,0.177985,0.00190625,1.01387 gb1_I232H,gb1_232,gb1,gb1,P06654,1.01387,NO,232,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-2.175,-4.687,2.512,,,,,,,0.766,,44.87,HHH,-2.152,0.177985,0.00580459,1.01387 PSD95pdz3_L360C,PSD95pdz3_360,PSD95pdz3,PSD95pdz3,P31016,1.01387,NO,360,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.431,-4.414,2.983,5.09284,,,,,14.2425,1.419,,86.88,HHP,-1.52667,0.0758425,0.000770471,1.01387 beta-lactamase_0_G281S,beta-lactamase_0_281,TEM-1,beta-lactamase_0,P62593,1.01388,NO,281,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-2.247,-3.28,1.033,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.0500837,0.0406482,1.01388 beta-lactamase_156_P217Y,beta-lactamase_156_217,TEM-1,beta-lactamase_156,P62593,1.01388,NO,217,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-2.062,-4.376,2.314,,0.496,I,A,0.52,-0.33,2.303,,74.48,OOH,-1.64333,0.111618,0.00463211,1.01388 beta-lactamase_E237Q,beta-lactamase_237,TEM-1,beta-lactamase,P62593,1.01388,NO,237,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.058,-3.881,1.823,5.42877,0.583,S,B,1.62,1.2,2.144,,77.62,OAB,-1.61467,0.221079,0.0048626,1.01388 kka2_1:8_P45A,kka2_1:8_45,Kka2,kka2_1:8,P00552,1.01388,NO,45,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.774,-2.227,0.453,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.100394,0.00590481,1.01388 kka2_1:8_P45A,kka2_1:8_45,Kka2,kka2_1:8,P00552,1.01388,NO,45,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.774,-2.227,0.453,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.100394,0.00590481,1.01388 PSD95pdz3_G319V,PSD95pdz3_319,PSD95pdz3,PSD95pdz3,P31016,1.0139,NO,319,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.008,-3.435,2.427,4.95387,,,,,18.8725,,,,BOP,-1.36967,0.0758425,0.00109317,1.0139 beta-lactamase_39_E279V,beta-lactamase_39_279,TEM-1,beta-lactamase_39,P62593,1.01392,NO,279,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.0495842,0.0192826,1.01392 beta-lactamase_39_L167T,beta-lactamase_39_167,TEM-1,beta-lactamase_39,P62593,1.01392,NO,167,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.138,-3.44,2.302,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.0495842,0.00303566,1.01392 beta-lactamase_156_I54F,beta-lactamase_156_54,TEM-1,beta-lactamase_156,P62593,1.01393,NO,54,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-2.838,-4.242,1.404,,0.669,E,B,0.48,-0.14,0.541,,73.78,BHH,-2.337,0.111618,0.00403589,1.01393 beta-lactamase_156_K109R,beta-lactamase_156_109,TEM-1,beta-lactamase_156,P62593,1.01394,NO,109,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.734,-2.595,0.861,,0.787,G,A,2.34,2.21,6.031,,72.73,ABB,-1.63333,0.111618,0.00462493,1.01394 beta-lactamase_39_R239Q,beta-lactamase_39_239,TEM-1,beta-lactamase_39,P62593,1.01394,NO,239,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.0495842,0.00213852,1.01394 beta-lactamase_625_L55I,beta-lactamase_625_55,TEM-1,beta-lactamase_625,P62593,1.01394,NO,55,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.86,-2.434,0.574,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.213352,0.00403741,1.01394 beta-lactamase_2500_K144I,beta-lactamase_2500_144,TEM-1,beta-lactamase_2500,P62593,1.01395,NO,144,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-2.388,-4.014,1.626,,0.863,H,A,2.34,1.27,0.515,,77.62,OBA,-1.904,0.361275,0.00481141,1.01395 kka2_1:4_A166E,kka2_1:4_166,Kka2,kka2_1:4,P00552,1.01395,NO,166,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.407,-2.752,0.345,,0.534,.,B,0.46,1.03,,,71.59,HHO,-2.421,0.168804,0.00799912,1.01395 beta-lactamase_156_L49V,beta-lactamase_156_49,TEM-1,beta-lactamase_156,P62593,1.01396,NO,49,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.897,-2.549,0.652,,0.131,T,A,0.55,0.04,3.112,,64.69,AHP,-1.99233,0.111618,0.00401477,1.01396 beta-lactamase_39_I277V,beta-lactamase_39_277,TEM-1,beta-lactamase_39,P62593,1.01397,NO,277,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.0495842,0.0169305,1.01397 beta-lactamase_F149W,beta-lactamase_149,TEM-1,beta-lactamase,P62593,1.01397,NO,149,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.299,-2.98,1.681,5.54789,0.195,H,A,1.1,0.11,1.863,,63.99,HHH,-1.46067,0.221079,0.00418462,1.01397 beta-lactamase_Q204L,beta-lactamase_204,TEM-1,beta-lactamase,P62593,1.01397,NO,204,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-1.382,-2.716,1.334,5.46394,0.204,H,A,0.12,0.09,1.707,,66.08,PPH,-1.49067,0.221079,0.00364106,1.01397 beta-lactamase_2500_A148L,beta-lactamase_2500_148,TEM-1,beta-lactamase_2500,P62593,1.01398,NO,148,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.757,-3.596,1.839,,0.379,H,A,0.46,-0.55,2.117,,72.73,PHH,-1.40167,0.361275,0.00547053,1.01398 PSD95pdz3_G319L,PSD95pdz3_319,PSD95pdz3,PSD95pdz3,P31016,1.01398,NO,319,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.008,-3.49,2.482,4.95387,,,,,18.8725,,,,BOP,-1.36967,0.0758425,0.00109317,1.01398 WW_domain_E178S,WW_domain_178,Yap65,WW_domain,P46937,1.01398,NO,178,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.158,-2.938,1.78,5.22323,,,,,,,,,HAH,-1.299,0.153962,0.0016738,1.01398 beta-lactamase_156_S283F,beta-lactamase_156_283,TEM-1,beta-lactamase_156,P62593,1.01399,NO,283,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.111618,0.0429138,1.01399 beta-lactamase_156_T27P,beta-lactamase_156_27,TEM-1,beta-lactamase_156,P62593,1.01399,NO,27,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.905,-1.921,0.016,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.111618,0.00306559,1.01399 beta-lactamase_39_T126G,beta-lactamase_39_126,TEM-1,beta-lactamase_39,P62593,1.01399,NO,126,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.122,-2.22,1.098,,0.05,H,A,0.22,-0.05,0.586,,44.41,HPH,-1.60467,0.0495842,0.00244552,1.01399 beta-lactamase_0_D155A,beta-lactamase_0_155,TEM-1,beta-lactamase_0,P62593,1.014,NO,155,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.889,-3.327,2.438,,0.049,,B,0.75,-0.9,16.833,16.833,64.69,OAB,-1.62267,0.0500837,0.00135315,1.014 beta-lactamase_0_V72L,beta-lactamase_0_72,TEM-1,beta-lactamase_0,P62593,1.014,NO,72,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.658,-2.403,0.745,,,H,A,0.44,-1.03,2.964,,65.73,BHH,-1.32167,0.0500837,0.00501194,1.014 beta-lactamase_39_A183M,beta-lactamase_39_183,TEM-1,beta-lactamase_39,P62593,1.014,NO,183,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.231,-4.59,3.359,,0.155,H,A,0.46,-0.91,1.237,,77.62,HHH,-1.53367,0.0495842,0.00296631,1.014 kka2_1:2_D157A,kka2_1:2_157,Kka2,kka2_1:2,P00552,1.014,NO,157,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.993,-3.298,2.305,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.295029,0.0042313,1.014 beta-lactamase_156_L55H,beta-lactamase_156_55,TEM-1,beta-lactamase_156,P62593,1.01401,NO,55,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.86,-4.855,2.995,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.111618,0.00403741,1.01401 beta-lactamase_39_H151C,beta-lactamase_39_151,TEM-1,beta-lactamase_39,P62593,1.01401,NO,151,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-2.96,-5.124,2.164,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.0495842,0.00216946,1.01401 beta-lactamase_39_P143E,beta-lactamase_39_143,TEM-1,beta-lactamase_39,P62593,1.01401,NO,143,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.967,-3.58,2.613,,0.075,H,A,0.52,-0.37,0.976,,66.78,OOB,-1.354,0.0495842,0.00114551,1.01401 beta-lactamase_39_R118V,beta-lactamase_39_118,TEM-1,beta-lactamase_39,P62593,1.01401,NO,118,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.413,-3.595,1.182,,0.457,H,A,1.2,1.39,3.961,,77.62,HBA,-1.785,0.0495842,0.00538794,1.01401 beta-lactamase_39_T126A,beta-lactamase_39_126,TEM-1,beta-lactamase_39,P62593,1.01401,NO,126,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.122,-2.955,1.833,,0.05,H,A,0.22,-0.05,0.586,,44.41,HPH,-1.60467,0.0495842,0.00244552,1.01401 beta-lactamase_39_I244V,beta-lactamase_39_244,TEM-1,beta-lactamase_39,P62593,1.01403,NO,244,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.555,-1.239,-0.316,,,E,B,0.48,-0.84,1.325,,77.62,OHH,-1.385,0.0495842,0.00605379,1.01403 beta-lactamase_39_R202V,beta-lactamase_39_202,TEM-1,beta-lactamase_39,P62593,1.01404,NO,202,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.292,-3.679,2.387,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.0495842,0.00321899,1.01404 beta-lactamase_625_P60N,beta-lactamase_625_60,TEM-1,beta-lactamase_625,P62593,1.01404,NO,60,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-2.469,-3.804,1.335,,0.256,T,A,0.52,-0.56,3.653,,77.62,BOA,-1.97633,0.213352,0.00521318,1.01404 beta-lactamase_39_A282Q,beta-lactamase_39_282,TEM-1,beta-lactamase_39,P62593,1.01405,NO,282,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.0495842,0.0449821,1.01405 PSD95pdz3_G322Q,PSD95pdz3_322,PSD95pdz3,PSD95pdz3,P31016,1.01405,NO,322,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.008,-3.806,2.798,5.24791,,,,,16.3275,,,,POH,-1.24867,0.0758425,0.00105821,1.01405 beta-lactamase_39_A230M,beta-lactamase_39_230,TEM-1,beta-lactamase_39,P62593,1.01406,NO,230,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.154,-4.69,3.536,,0.01,E,B,0.46,-1.17,1.171,,50,HHA,-1.079,0.0495842,0.00516841,1.01406 beta-lactamase_625_R159N,beta-lactamase_625_159,TEM-1,beta-lactamase_625,P62593,1.01406,NO,159,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-0.94,-3.445,2.505,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.213352,0.00108472,1.01406 beta-lactamase_0_N50V,beta-lactamase_0_50,TEM-1,beta-lactamase_0,P62593,1.01407,NO,50,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-2.979,-2.913,-0.066,,0.912,T,A,0.61,1.24,9.874,9.874,77.62,HPP,-2.134,0.0500837,0.0047211,1.01407 beta-lactamase_156_F149W,beta-lactamase_156_149,TEM-1,beta-lactamase_156,P62593,1.01407,NO,149,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.299,-2.98,1.681,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.111618,0.00418462,1.01407 beta-lactamase_2500_A211G,beta-lactamase_2500_211,TEM-1,beta-lactamase_2500,P62593,1.01407,NO,211,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.896,-2.355,0.459,,0.369,T,A,0.46,-0.69,2.061,,77.62,AHA,-1.94633,0.361275,0.00648183,1.01407 beta-lactamase_625_R275T,beta-lactamase_625_275,TEM-1,beta-lactamase_625,P62593,1.01407,NO,275,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.213352,0.0141984,1.01407 beta-lactamase_625_V29W,beta-lactamase_625_29,TEM-1,beta-lactamase_625,P62593,1.01407,NO,29,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-2.856,-5.465,2.609,,0.733,H,A,0.44,-0.78,1.931,,93.01,HHB,-2.24733,0.213352,0.00318969,1.01407 PSD95pdz3_S371K,PSD95pdz3_371,PSD95pdz3,PSD95pdz3,P31016,1.01407,NO,371,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.86,-3.138,1.278,5.19744,,,,,17.1117,3.854,,87.71,HPB,-1.598,0.0758425,0.000847873,1.01407 beta-lactamase_39_E46C,beta-lactamase_39_46,TEM-1,beta-lactamase_39,P62593,1.01408,NO,46,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.94,-3.249,1.309,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.0495842,0.00427568,1.01408 beta-lactamase_625_A282W,beta-lactamase_625_282,TEM-1,beta-lactamase_625,P62593,1.01408,NO,282,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.213352,0.0449821,1.01408 beta-lactamase_625_E108P,beta-lactamase_625_108,TEM-1,beta-lactamase_625,P62593,1.01408,NO,108,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.46,-3.855,2.395,,0.572,G,A,1.04,1.87,20.151,20.151,72.73,PAB,-1.437,0.213352,0.00413372,1.01408 kka2_1:8_Q155H,kka2_1:8_155,Kka2,kka2_1:8,P00552,1.01408,NO,155,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.606,-4.51,1.904,,0.525,T,A,0.64,1.49,,,63.64,APA,-1.726,0.100394,0.00641853,1.01408 kka2_1:8_Q155H,kka2_1:8_155,Kka2,kka2_1:8,P00552,1.01408,NO,155,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.606,-4.51,1.904,,0.525,T,A,0.64,1.49,,,63.64,APA,-1.726,0.100394,0.00641853,1.01408 beta-lactamase_156_F149Y,beta-lactamase_156_149,TEM-1,beta-lactamase_156,P62593,1.01409,NO,149,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.299,-1.705,0.406,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.111618,0.00418462,1.01409 beta-lactamase_156_Q86T,beta-lactamase_156_86,TEM-1,beta-lactamase_156,P62593,1.01409,NO,86,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.4,-2.587,0.187,,0.696,S,A,0.64,2.38,27.704,27.704,77.62,OPA,-1.61067,0.111618,0.00450027,1.01409 beta-lactamase_156_V29K,beta-lactamase_156_29,TEM-1,beta-lactamase_156,P62593,1.01409,NO,29,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-2.856,-2.195,-0.661,,0.733,H,A,0.44,-0.78,3.685,,93.01,HHB,-2.24733,0.111618,0.00318969,1.01409 beta-lactamase_39_A200E,beta-lactamase_39_200,TEM-1,beta-lactamase_39,P62593,1.01409,NO,200,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.878,-2.662,0.784,,0.757,H,A,0.46,-0.19,1.54,,77.62,HHP,-2.001,0.0495842,0.0060056,1.01409 beta-lactamase_F22W,beta-lactamase_22,TEM-1,beta-lactamase,P62593,1.01409,NO,22,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-2.676,-3.23,0.554,,,,,,,1.616,,73.08,HHH,-2.03233,0.221079,0.00262842,1.01409 kka2_1:8_D134P,kka2_1:8_134,Kka2,kka2_1:8,P00552,1.01409,NO,134,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.969,-3.811,2.842,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.100394,0.00270812,1.01409 kka2_1:8_D134P,kka2_1:8_134,Kka2,kka2_1:8,P00552,1.01409,NO,134,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.969,-3.811,2.842,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.100394,0.00270812,1.01409 beta-lactamase_39_E108L,beta-lactamase_39_108,TEM-1,beta-lactamase_39,P62593,1.0141,NO,108,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.46,-3.653,2.193,,0.572,G,A,1.04,1.87,20.151,20.151,72.73,PAB,-1.437,0.0495842,0.00413372,1.0141 beta-lactamase_39_G194Y,beta-lactamase_39_194,TEM-1,beta-lactamase_39,P62593,1.0141,NO,194,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.396,-4.427,3.031,,0.276,S,b,0.29,0.36,4.852,,67.83,POA,-1.832,0.0495842,0.00392163,1.0141 beta-lactamase_625_V259A,beta-lactamase_625_259,TEM-1,beta-lactamase_625,P62593,1.0141,NO,259,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.213352,0.0070773,1.0141 beta-lactamase_625_G141H,beta-lactamase_625_141,TEM-1,beta-lactamase_625,P62593,1.01411,NO,141,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.828,-4.652,3.824,,0.575,T,l,0.29,-0.28,0.198,,64.69,HOO,-1.08933,0.213352,0.0012419,1.01411 beta-lactamase_156_A84S,beta-lactamase_156_84,TEM-1,beta-lactamase_156,P62593,1.01412,NO,84,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.651,-2.609,0.958,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.111618,0.00503822,1.01412 beta-lactamase_625_E166D,beta-lactamase_625_166,TEM-1,beta-lactamase_625,P62593,1.01413,NO,166,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.756,-2.259,0.503,,0.508,G,A,1.04,1.05,2.124,,73.08,OAH,-1.42233,0.213352,0.00512989,1.01413 PSD95pdz3_I377G,PSD95pdz3_377,PSD95pdz3,PSD95pdz3,P31016,1.01413,NO,377,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.873,-3.374,1.501,4.9532,,,,,19.185,2.364,,87.71,HHH,-1.49567,0.0758425,0.000795475,1.01413 beta-lactamase_156_E238D,beta-lactamase_156_238,TEM-1,beta-lactamase_156,P62593,1.01414,NO,238,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.111618,0.00743256,1.01414 beta-lactamase_0_L188G,beta-lactamase_0_188,TEM-1,beta-lactamase_0,P62593,1.01415,NO,188,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.166,-3.699,2.533,,,H,A,0.55,-0.3,2.739,,60.14,PHB,-1.47033,0.0500837,0.00295687,1.01415 beta-lactamase_156_V214I,beta-lactamase_156_214,TEM-1,beta-lactamase_156,P62593,1.01415,NO,214,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.299,-3.053,1.754,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.111618,0.00628442,1.01415 beta-lactamase_39_L74G,beta-lactamase_39_74,TEM-1,beta-lactamase_39,P62593,1.01415,NO,74,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.296,-3.477,2.181,,,H,A,0.55,-0.91,1.581,,50,HHO,-1.34933,0.0495842,0.00493255,1.01415 beta-lactamase_39_T186I,beta-lactamase_39_186,TEM-1,beta-lactamase_39,P62593,1.01415,NO,186,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.522,-3.94,1.418,,0.396,H,A,0.22,-0.28,0.515,,77.62,HPP,-1.77633,0.0495842,0.00485034,1.01415 beta-lactamase_156_K109A,beta-lactamase_156_109,TEM-1,beta-lactamase_156,P62593,1.01416,NO,109,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.734,-3.283,1.549,,0.787,G,A,2.34,2.21,6.031,,72.73,ABB,-1.63333,0.111618,0.00462493,1.01416 beta-lactamase_625_P60W,beta-lactamase_625_60,TEM-1,beta-lactamase_625,P62593,1.01416,NO,60,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-2.469,-5.456,2.987,,0.256,T,A,0.52,-0.56,3.653,,77.62,BOA,-1.97633,0.213352,0.00521318,1.01416 beta-lactamase_R92I,beta-lactamase_92,TEM-1,beta-lactamase,P62593,1.01416,NO,92,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.718,-3.773,2.055,5.65832,0.479,E,B,0.91,1.36,3.069,,65.38,BBH,-1.50367,0.221079,0.00429626,1.01416 beta-lactamase_39_L55I,beta-lactamase_39_55,TEM-1,beta-lactamase_39,P62593,1.01417,NO,55,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.86,-2.434,0.574,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.0495842,0.00403741,1.01417 beta-lactamase_39_V82Q,beta-lactamase_39_82,TEM-1,beta-lactamase_39,P62593,1.01417,NO,82,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.325,-4.196,2.871,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.0495842,0.00397046,1.01417 beta-lactamase_L219I,beta-lactamase_219,TEM-1,beta-lactamase,P62593,1.01417,NO,219,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.313,-1.692,0.379,5.74153,,I,A,0.84,-0.51,2.321,,74.48,HHB,-1.21533,0.221079,0.00664345,1.01417 beta-lactamase_0_L49Y,beta-lactamase_0_49,TEM-1,beta-lactamase_0,P62593,1.01419,NO,49,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.897,-4.158,2.261,,0.131,T,A,0.55,0.04,13.838,13.838,64.69,AHP,-1.99233,0.0500837,0.00401477,1.01419 beta-lactamase_625_P217S,beta-lactamase_625_217,TEM-1,beta-lactamase_625,P62593,1.0142,NO,217,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-2.062,-2.615,0.553,,0.496,I,A,0.52,-0.33,1.087,,74.48,OOH,-1.64333,0.213352,0.00463211,1.0142 beta-lactamase_K190T,beta-lactamase_190,TEM-1,beta-lactamase,P62593,1.0142,NO,190,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.994,-2.389,0.395,5.49163,0.371,H,A,1.82,0.16,29.753,29.753,77.62,BBH,-1.64167,0.221079,0.00574527,1.0142 beta-lactamase_39_L137E,beta-lactamase_39_137,TEM-1,beta-lactamase_39,P62593,1.01421,NO,137,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.03,-3.919,2.889,,,H,A,0.55,-0.38,0.674,,42.31,HHP,-1.58933,0.0495842,0.00278599,1.01421 beta-lactamase_39_P143A,beta-lactamase_39_143,TEM-1,beta-lactamase_39,P62593,1.01421,NO,143,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.967,-3.126,2.159,,0.075,H,A,0.52,-0.37,0.976,,66.78,OOB,-1.354,0.0495842,0.00114551,1.01421 beta-lactamase_39_E175M,beta-lactamase_39_175,TEM-1,beta-lactamase_39,P62593,1.01422,NO,175,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.336,-3.397,1.061,,0.551,,A,1.04,1.05,3.676,,77.62,AAB,-1.31233,0.0495842,0.00482205,1.01422 beta-lactamase_39_V42M,beta-lactamase_39_42,TEM-1,beta-lactamase_39,P62593,1.01422,NO,42,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.564,-2.813,1.249,,0.017,E,B,0.44,-0.51,1.86,,63.99,BHO,-1.042,0.0495842,0.00404515,1.01422 beta-lactamase_625_K109C,beta-lactamase_625_109,TEM-1,beta-lactamase_625,P62593,1.01422,NO,109,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.734,-5.237,3.503,,0.787,G,A,2.34,2.21,7.243,,72.73,ABB,-1.63333,0.213352,0.00462493,1.01422 beta-lactamase_0_P181R,beta-lactamase_0_181,TEM-1,beta-lactamase_0,P62593,1.01423,NO,181,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.813,-3.93,3.117,,,H,A,0.52,-1.14,1.357,,61.54,HOH,-1.795,0.0500837,0.000703122,1.01423 beta-lactamase_156_M67G,beta-lactamase_156_67,TEM-1,beta-lactamase_156,P62593,1.01425,NO,67,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-2.231,-2.754,0.523,,0.006,G,P,0.55,-0.81,1.463,,65.03,HHP,-1.502,0.111618,0.00409753,1.01425 beta-lactamase_A246L,beta-lactamase_246,TEM-1,beta-lactamase,P62593,1.01425,NO,246,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.121,-1.908,-0.213,4.78979,0.01,E,B,0.52,-1.01,1.26,,73.78,HHH,-1.55633,0.221079,0.00569458,1.01425 beta-lactamase_39_P25V,beta-lactamase_39_25,TEM-1,beta-lactamase_39,P62593,1.01426,NO,25,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.526,-3.565,2.039,,0.624,H,A,0.52,0.14,1.157,,73.08,BOA,-2.15367,0.0495842,0.00347571,1.01426 beta-lactamase_625_A84L,beta-lactamase_625_84,TEM-1,beta-lactamase_625,P62593,1.01427,NO,84,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.651,-3.508,1.857,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.213352,0.00503822,1.01427 beta-lactamase_39_M66T,beta-lactamase_39_66,TEM-1,beta-lactamase_39,P62593,1.01428,NO,66,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.362,-3.498,2.136,,0.013,,A,0.55,-0.7,1.319,,73.08,OHH,-1.49567,0.0495842,0.00412876,1.01428 beta-lactamase_39_P25D,beta-lactamase_39_25,TEM-1,beta-lactamase_39,P62593,1.01428,NO,25,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.526,-2.562,1.036,,0.624,H,A,0.52,0.14,1.157,,73.08,BOA,-2.15367,0.0495842,0.00347571,1.01428 beta-lactamase_156_Q204N,beta-lactamase_156_204,TEM-1,beta-lactamase_156,P62593,1.01429,NO,204,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-1.382,-3.623,2.241,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.111618,0.00364106,1.01429 beta-lactamase_39_A282L,beta-lactamase_39_282,TEM-1,beta-lactamase_39,P62593,1.01429,NO,282,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.586,-3.183,1.597,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.0495842,0.0449821,1.01429 kka2_1:4_M197I,kka2_1:4_197,Kka2,kka2_1:4,P00552,1.01429,NO,197,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.707,-1.88,0.173,,0.121,E,B,0.55,-1.19,0.415,,65.53,HHH,-1.847,0.168804,0.00921295,1.01429 beta-lactamase_156_D271C,beta-lactamase_156_271,TEM-1,beta-lactamase_156,P62593,1.0143,NO,271,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.111618,0.00752082,1.0143 beta-lactamase_625_T116N,beta-lactamase_625_116,TEM-1,beta-lactamase_625,P62593,1.0143,NO,116,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.28,-2.515,1.235,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.213352,0.00336175,1.0143 beta-lactamase_I206M,beta-lactamase_206,TEM-1,beta-lactamase,P62593,1.0143,NO,206,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-2.429,-3.069,0.64,5.3727,0.173,H,A,1,-0.34,2.061,,77.62,HHA,-1.805,0.221079,0.00528934,1.0143 PSD95pdz3_L353M,PSD95pdz3_353,PSD95pdz3,PSD95pdz3,P31016,1.0143,NO,353,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.347,-3.487,2.14,5.81136,,,,,17.3525,,,,AHB,-1.50533,0.0758425,0.000664742,1.0143 beta-lactamase_0_Q88P,beta-lactamase_0_88,TEM-1,beta-lactamase_0,P62593,1.01431,NO,88,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.086,-3.948,1.862,,0.807,,B,0.64,2.03,0.4,,77.62,APH,-1.53433,0.0500837,0.00504167,1.01431 beta-lactamase_156_R202E,beta-lactamase_156_202,TEM-1,beta-lactamase_156,P62593,1.01431,NO,202,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.292,-3.173,1.881,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.111618,0.00321899,1.01431 beta-lactamase_39_R275Y,beta-lactamase_39_275,TEM-1,beta-lactamase_39,P62593,1.01431,NO,275,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.0495842,0.0141984,1.01431 beta-lactamase_625_Q88R,beta-lactamase_625_88,TEM-1,beta-lactamase_625,P62593,1.01431,NO,88,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.086,-2.458,0.372,,0.807,,B,0.64,2.03,1.84,,77.62,APH,-1.53433,0.213352,0.00504167,1.01431 beta-lactamase_0_A247V,beta-lactamase_0_247,TEM-1,beta-lactamase_0,P62593,1.01432,NO,247,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.0500837,0.00611275,1.01432 beta-lactamase_156_A182H,beta-lactamase_156_182,TEM-1,beta-lactamase_156,P62593,1.01432,NO,182,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.777,-3.358,1.581,,0.136,H,A,0.46,-0.66,16.784,16.784,93.01,OHH,-1.27367,0.111618,0.00559099,1.01432 beta-lactamase_156_E279T,beta-lactamase_156_279,TEM-1,beta-lactamase_156,P62593,1.01432,NO,279,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.111618,0.0192826,1.01432 beta-lactamase_625_V29L,beta-lactamase_625_29,TEM-1,beta-lactamase_625,P62593,1.01432,NO,29,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-2.856,-3.547,0.691,,0.733,H,A,0.44,-0.78,1.931,,93.01,HHB,-2.24733,0.213352,0.00318969,1.01432 beta-lactamase_156_S201A,beta-lactamase_156_201,TEM-1,beta-lactamase_156,P62593,1.01433,NO,201,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.183,-2.127,0.944,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.111618,0.00198815,1.01433 beta-lactamase_39_P60L,beta-lactamase_39_60,TEM-1,beta-lactamase_39,P62593,1.01433,NO,60,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-2.469,-2.818,0.349,,0.256,T,A,0.52,-0.56,21.37,21.37,77.62,BOA,-1.97633,0.0495842,0.00521318,1.01433 PSD95pdz3_L349Y,PSD95pdz3_349,PSD95pdz3,PSD95pdz3,P31016,1.01433,NO,349,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.347,-3.619,2.272,5.14696,,,,,24.6438,,,,AHP,-1.37667,0.0758425,0.00071841,1.01433 beta-lactamase_0_K109Y,beta-lactamase_0_109,TEM-1,beta-lactamase_0,P62593,1.01434,NO,109,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.734,-4.334,2.6,,0.787,G,A,2.34,2.21,15.473,15.473,72.73,ABB,-1.63333,0.0500837,0.00462493,1.01434 beta-lactamase_156_K53D,beta-lactamase_156_53,TEM-1,beta-lactamase_156,P62593,1.01434,NO,53,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-2.313,-3.725,1.412,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.111618,0.00383383,1.01434 beta-lactamase_156_R239L,beta-lactamase_156_239,TEM-1,beta-lactamase_156,P62593,1.01434,NO,239,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.111618,0.00213852,1.01434 beta-lactamase_2500_L199K,beta-lactamase_2500_199,TEM-1,beta-lactamase_2500,P62593,1.01435,NO,199,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-2.942,-2.994,0.052,,0.832,H,A,0.55,0.42,15.504,15.504,77.62,PHH,-2.32933,0.361275,0.0048649,1.01435 beta-lactamase_39_N274D,beta-lactamase_39_274,TEM-1,beta-lactamase_39,P62593,1.01435,NO,274,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.0495842,0.0110418,1.01435 kka2_1:8_L174V,kka2_1:8_174,Kka2,kka2_1:8,P00552,1.01435,NO,174,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.952,-2.256,1.304,,,H,A,1.59,-0.31,1.204,,51.89,BHB,-2.08533,0.100394,0.00438501,1.01435 kka2_1:8_L174V,kka2_1:8_174,Kka2,kka2_1:8,P00552,1.01435,NO,174,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.952,-2.256,1.304,,,H,A,1.59,-0.31,1.204,,51.89,BHB,-2.08533,0.100394,0.00438501,1.01435 beta-lactamase_156_L196H,beta-lactamase_156_196,TEM-1,beta-lactamase_156,P62593,1.01436,NO,196,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-2.478,-3.478,1,,0.518,S,A,0.55,1.35,7.897,,77.62,AHH,-1.839,0.111618,0.00512144,1.01436 beta-lactamase_156_I261A,beta-lactamase_156_261,TEM-1,beta-lactamase_156,P62593,1.01437,NO,261,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.111618,0.0123091,1.01437 beta-lactamase_156_H156N,beta-lactamase_156_156,TEM-1,beta-lactamase_156,P62593,1.01438,NO,156,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-3.156,-2.52,-0.636,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.111618,0.00468596,1.01438 beta-lactamase_156_L100M,beta-lactamase_156_100,TEM-1,beta-lactamase_156,P62593,1.01438,NO,100,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.218,-4.039,2.821,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.111618,0.00413885,1.01438 beta-lactamase_625_E46Y,beta-lactamase_625_46,TEM-1,beta-lactamase_625,P62593,1.01438,NO,46,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.94,-4.198,2.258,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.213352,0.00427568,1.01438 kka2_1:2_L81M,kka2_1:2_81,Kka2,kka2_1:2,P00552,1.01438,NO,81,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.427,-2.896,1.469,,0.46,E,A,1.59,-0.14,1.895,,63.64,HHA,-1.50567,0.295029,0.00805839,1.01438 beta-lactamase_0_T264V,beta-lactamase_0_264,TEM-1,beta-lactamase_0,P62593,1.0144,NO,264,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.0500837,0.0119399,1.0144 beta-lactamase_156_A170R,beta-lactamase_156_170,TEM-1,beta-lactamase_156,P62593,1.0144,NO,170,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.237,-3.908,2.671,,0.126,,L,0.46,-0.35,3.7,,64.69,AHH,-1.63267,0.111618,0.00431903,1.0144 beta-lactamase_39_G236M,beta-lactamase_39_236,TEM-1,beta-lactamase_39,P62593,1.0144,NO,236,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.784,-4.869,4.085,,0.241,,b,0.29,-0.59,1.883,,64.69,HOO,-1.025,0.0495842,0.00162372,1.0144 beta-lactamase_A222Q,beta-lactamase_222,TEM-1,beta-lactamase,P62593,1.0144,NO,222,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.103,-4.105,2.002,5.2262,0.233,H,A,0.47,-0.25,0.379,,77.62,PHH,-1.63733,0.221079,0.00466094,1.0144 beta-lactamase_N50E,beta-lactamase_50,TEM-1,beta-lactamase,P62593,1.0144,NO,50,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-2.979,-2.315,-0.664,5.51261,0.912,T,A,1.07,1.24,1.581,,77.62,HPP,-2.134,0.221079,0.0047211,1.0144 beta-lactamase_P217K,beta-lactamase_217,TEM-1,beta-lactamase,P62593,1.0144,NO,217,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-2.062,-2.687,0.625,5.19872,0.496,I,A,0.99,-0.33,0.431,,74.48,OOH,-1.64333,0.221079,0.00463211,1.0144 beta-lactamase_S281K,beta-lactamase_281,TEM-1,beta-lactamase,P62593,1.0144,NO,281,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.247,-3.618,1.371,4.73591,0.128,H,A,0.25,-0.26,2.144,,77.62,HPH,-1.847,0.221079,0.0406482,1.0144 beta-lactamase_V42F,beta-lactamase_42,TEM-1,beta-lactamase,P62593,1.0144,NO,42,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.564,-3.895,2.331,5.27904,0.017,E,B,1.64,-0.51,2.024,,63.99,BHO,-1.042,0.221079,0.00404515,1.0144 beta-lactamase_V8C,beta-lactamase_8,TEM-1,beta-lactamase,P62593,1.0144,NO,8,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-2.358,-4.764,2.406,,,,,,,0.575,,77.62,BHH,-2.06267,0.221079,0.00226401,1.0144 PSD95pdz3_N381F,PSD95pdz3_381,PSD95pdz3,PSD95pdz3,P31016,1.0144,NO,381,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-1.41,-3.974,2.564,5.66057,,,,,28.2162,,,,BPH,-1.37767,0.0758425,0.000265374,1.0144 beta-lactamase_39_E56Y,beta-lactamase_39_56,TEM-1,beta-lactamase_39,P62593,1.01441,NO,56,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.043,-4.216,2.173,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.0495842,0.00238534,1.01441 beta-lactamase_625_L28G,beta-lactamase_625_28,TEM-1,beta-lactamase_625,P62593,1.01441,NO,28,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.579,-3.602,2.023,,0.277,H,A,0.55,-0.16,2.716,,93.01,PHH,-2.11333,0.213352,0.00359321,1.01441 beta-lactamase_625_P25M,beta-lactamase_625_25,TEM-1,beta-lactamase_625,P62593,1.01442,NO,25,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.526,-4.708,3.182,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.213352,0.00347571,1.01442 beta-lactamase_625_Q88V,beta-lactamase_625_88,TEM-1,beta-lactamase_625,P62593,1.01442,NO,88,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.086,-3.621,1.535,,0.807,,B,0.64,2.03,1.84,,77.62,APH,-1.53433,0.213352,0.00504167,1.01442 beta-lactamase_625_T112H,beta-lactamase_625_112,TEM-1,beta-lactamase_625,P62593,1.01443,NO,112,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.186,-4.734,2.548,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.213352,0.00531334,1.01443 beta-lactamase_156_I171N,beta-lactamase_156_171,TEM-1,beta-lactamase_156,P62593,1.01445,NO,171,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-2.431,-3.904,1.473,,0.361,,B,0.48,0.53,3.869,,77.62,HHO,-1.55533,0.111618,0.00623355,1.01445 beta-lactamase_156_R242Q,beta-lactamase_156_242,TEM-1,beta-lactamase_156,P62593,1.01445,NO,242,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.111618,0.00452879,1.01445 beta-lactamase_39_N173Y,beta-lactamase_39_173,TEM-1,beta-lactamase_39,P62593,1.01446,NO,173,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-2.663,-4.409,1.746,,1.044,T,l,0.61,1.25,1.426,,77.62,OPA,-1.46633,0.0495842,0.0033769,1.01446 gb1_T243Q,gb1_243,gb1,gb1,P06654,1.01446,NO,243,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.415,-3.71,2.295,,,,,,,1.083,,37.28,PPP,-1.43233,0.177985,0.00308687,1.01446 kka2_1:8_S114L,kka2_1:8_114,Kka2,kka2_1:8,P00552,1.01446,NO,114,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.527,-3.038,0.511,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.100394,0.00705262,1.01446 kka2_1:8_S114L,kka2_1:8_114,Kka2,kka2_1:8,P00552,1.01446,NO,114,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.527,-3.038,0.511,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.100394,0.00705262,1.01446 PSD95pdz3_K355Q,PSD95pdz3_355,PSD95pdz3,PSD95pdz3,P31016,1.01447,NO,355,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.416,-3.131,1.715,5.56865,,,,,17.2556,,,,BBO,-1.33533,0.0758425,0.00063703,1.01447 PSD95pdz3_S371E,PSD95pdz3_371,PSD95pdz3,PSD95pdz3,P31016,1.01447,NO,371,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.86,-3.121,1.261,5.19744,,,,,17.1117,3.854,,87.71,HPB,-1.598,0.0758425,0.000847873,1.01447 beta-lactamase_156_R275T,beta-lactamase_156_275,TEM-1,beta-lactamase_156,P62593,1.01448,NO,275,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.111618,0.0141984,1.01448 beta-lactamase_156_R92W,beta-lactamase_156_92,TEM-1,beta-lactamase_156,P62593,1.01448,NO,92,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.718,-5.477,3.759,,0.479,E,B,1.2,1.36,19.112,19.112,65.38,BBH,-1.50367,0.111618,0.00429626,1.01448 beta-lactamase_2500_S96Q,beta-lactamase_2500_96,TEM-1,beta-lactamase_2500,P62593,1.01448,NO,96,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.27,-2.919,0.649,,0.368,,b,0.27,0.39,32.348,32.348,73.78,HPP,-2.019,0.361275,0.00551835,1.01448 beta-lactamase_2500_T186L,beta-lactamase_2500_186,TEM-1,beta-lactamase_2500,P62593,1.01448,NO,186,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.522,-2.882,0.36,,0.396,H,A,0.22,-0.28,2.144,,77.62,HPP,-1.77633,0.361275,0.00485034,1.01448 beta-lactamase_625_E26N,beta-lactamase_625_26,TEM-1,beta-lactamase_625,P62593,1.01448,NO,26,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.454,-3.711,1.257,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.213352,0.00297948,1.01448 beta-lactamase_E56E,beta-lactamase_56,TEM-1,beta-lactamase,P62593,1.01448,NO,56,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.043,-2.043,,5.65281,0.198,E,B,0.52,0.31,2.022,,72.73,HAP,-1.94033,0.221079,0.00238534,1.01448 beta-lactamase_0_G253N,beta-lactamase_0_253,TEM-1,beta-lactamase_0,P62593,1.01449,NO,253,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.0500837,0.00786358,1.01449 beta-lactamase_156_G216F,beta-lactamase_156_216,TEM-1,beta-lactamase_156,P62593,1.0145,NO,216,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.477,-4.417,2.94,,0.437,I,A,0.29,-0.58,12.464,12.464,74.48,HOO,-1.68067,0.111618,0.00639568,1.0145 beta-lactamase_M180C,beta-lactamase_180,TEM-1,beta-lactamase,P62593,1.0145,NO,180,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-2.795,-4.786,1.991,4.96809,0.242,,B,1.07,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.221079,0.00552048,1.0145 beta-lactamase_2500_T186A,beta-lactamase_2500_186,TEM-1,beta-lactamase_2500,P62593,1.01451,NO,186,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.522,-1.898,-0.624,,0.396,H,A,0.22,-0.28,2.144,,77.62,HPP,-1.77633,0.361275,0.00485034,1.01451 beta-lactamase_156_S80H,beta-lactamase_156_80,TEM-1,beta-lactamase_156,P62593,1.01452,NO,80,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.029,-3.359,1.33,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.111618,0.00565569,1.01452 beta-lactamase_2500_R118E,beta-lactamase_2500_118,TEM-1,beta-lactamase_2500,P62593,1.01452,NO,118,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.413,-2.454,0.041,,0.457,H,A,1.2,1.39,2.144,,77.62,HBA,-1.785,0.361275,0.00538794,1.01452 beta-lactamase_625_V29G,beta-lactamase_625_29,TEM-1,beta-lactamase_625,P62593,1.01452,NO,29,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-2.856,-2.66,-0.196,,0.733,H,A,0.44,-0.78,1.931,,93.01,HHB,-2.24733,0.213352,0.00318969,1.01452 kka2_1:4_P76S,kka2_1:4_76,Kka2,kka2_1:4,P00552,1.01452,NO,76,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.449,-2.672,1.223,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.168804,0.00625685,1.01452 beta-lactamase_0_A77P,beta-lactamase_0_77,TEM-1,beta-lactamase_0,P62593,1.01453,NO,77,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.234,-3.879,2.645,,0.039,H,A,0.46,-0.56,2.591,,64.34,OHH,-1.294,0.0500837,0.00282362,1.01453 beta-lactamase_156_T179C,beta-lactamase_156_179,TEM-1,beta-lactamase_156,P62593,1.01453,NO,179,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.085,-4.712,3.627,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.111618,0.00226045,1.01453 beta-lactamase_2500_T112F,beta-lactamase_2500_112,TEM-1,beta-lactamase_2500,P62593,1.01453,NO,112,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.186,-4.382,2.196,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.361275,0.00531334,1.01453 beta-lactamase_39_Q204F,beta-lactamase_39_204,TEM-1,beta-lactamase_39,P62593,1.01453,NO,204,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-1.382,-4.303,2.921,,0.204,H,A,0.64,0.09,0.489,,66.08,PPH,-1.49067,0.0495842,0.00364106,1.01453 beta-lactamase_0_E169G,beta-lactamase_0_169,TEM-1,beta-lactamase_0,P62593,1.01454,NO,169,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.23,-3.348,2.118,,0.337,,A,1.04,1,3.516,,73.08,PAH,-1.16533,0.0500837,0.00400994,1.01454 beta-lactamase_156_T131L,beta-lactamase_156_131,TEM-1,beta-lactamase_156,P62593,1.01454,NO,131,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.328,-3.319,1.991,,,H,A,0.22,-0.69,2.031,,67.48,PPH,-1.00867,0.111618,0.00345886,1.01454 beta-lactamase_625_S201Q,beta-lactamase_625_201,TEM-1,beta-lactamase_625,P62593,1.01454,NO,201,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.183,-2.836,1.653,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.213352,0.00198815,1.01454 beta-lactamase_A15L,beta-lactamase_15,TEM-1,beta-lactamase,P62593,1.01454,NO,15,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.654,-2.458,0.804,,,,,,,31.998,31.998,93.01,HHH,-2.10833,0.221079,0.00248966,1.01454 beta-lactamase_0_G243L,beta-lactamase_0_243,TEM-1,beta-lactamase_0,P62593,1.01455,NO,243,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.0500837,0.00464034,1.01455 Pab1_Q194E,Pab1_194,Pab1,Pab1,P04147,1.01455,NO,194,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.179,-3.241,1.062,,,,,,,,,,OPA,-1.59767,0.175299,0.0016145,1.01455 beta-lactamase_0_E169V,beta-lactamase_0_169,TEM-1,beta-lactamase_0,P62593,1.01457,NO,169,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.23,-3.538,2.308,,0.337,,A,1.04,1,3.516,,73.08,PAH,-1.16533,0.0500837,0.00400994,1.01457 beta-lactamase_156_M270N,beta-lactamase_156_270,TEM-1,beta-lactamase_156,P62593,1.01457,NO,270,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.111618,0.00767762,1.01457 beta-lactamase_39_E102Y,beta-lactamase_39_102,TEM-1,beta-lactamase_39,P62593,1.01457,NO,102,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.118,-4.321,2.203,,0.722,S,B,1.04,1.82,3.87,,73.08,HAH,-1.581,0.0495842,0.00486633,1.01457 beta-lactamase_156_D271A,beta-lactamase_156_271,TEM-1,beta-lactamase_156,P62593,1.01458,NO,271,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.111618,0.00752082,1.01458 beta-lactamase_156_A200F,beta-lactamase_156_200,TEM-1,beta-lactamase_156,P62593,1.01459,NO,200,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.878,-4.397,2.519,,0.757,H,A,0.46,-0.19,16.368,16.368,77.62,HHP,-2.001,0.111618,0.0060056,1.01459 beta-lactamase_39_M127S,beta-lactamase_39_127,TEM-1,beta-lactamase_39,P62593,1.01459,NO,127,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-2.251,-3.644,1.393,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.0495842,0.00437927,1.01459 beta-lactamase_625_P60R,beta-lactamase_625_60,TEM-1,beta-lactamase_625,P62593,1.01459,NO,60,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-2.469,-3.014,0.545,,0.256,T,A,0.52,-0.56,3.653,,77.62,BOA,-1.97633,0.213352,0.00521318,1.01459 beta-lactamase_N152T,beta-lactamase_152,TEM-1,beta-lactamase,P62593,1.01459,NO,152,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-2.757,-2.377,-0.38,5.98571,0.863,H,A,0.09,0.92,2.061,,77.62,BPH,-2.97,0.221079,0.00471429,1.01459 beta-lactamase_625_A183F,beta-lactamase_625_183,TEM-1,beta-lactamase_625,P62593,1.01461,NO,183,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.231,-4.164,2.933,,0.155,H,A,0.46,-0.91,23.859,23.859,77.62,HHH,-1.53367,0.213352,0.00296631,1.01461 beta-lactamase_39_E166Q,beta-lactamase_39_166,TEM-1,beta-lactamase_39,P62593,1.01462,NO,166,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.756,-3.022,1.266,,0.508,G,A,1.04,1.05,17.227,17.227,73.08,OAH,-1.42233,0.0495842,0.00512989,1.01462 beta-lactamase_39_G85E,beta-lactamase_39_85,TEM-1,beta-lactamase_39,P62593,1.01463,NO,85,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.011,-3.408,2.397,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.0495842,0.00252173,1.01463 beta-lactamase_156_D271F,beta-lactamase_156_271,TEM-1,beta-lactamase_156,P62593,1.01464,NO,271,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.111618,0.00752082,1.01464 beta-lactamase_156_V106I,beta-lactamase_156_106,TEM-1,beta-lactamase_156,P62593,1.01464,NO,106,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.218,-2.124,0.906,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.111618,0.00304168,1.01464 beta-lactamase_39_L89A,beta-lactamase_39_89,TEM-1,beta-lactamase_39,P62593,1.01464,NO,89,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.096,-2.465,1.369,,0.168,T,A,0.55,0.63,3.233,,64.34,PHO,-1.75767,0.0495842,0.00207068,1.01464 beta-lactamase_39_L100E,beta-lactamase_39_100,TEM-1,beta-lactamase_39,P62593,1.01465,NO,100,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.218,-3.935,2.717,,0.343,,B,0.55,0.13,8.311,,63.29,AHH,-1.23467,0.0495842,0.00413885,1.01465 beta-lactamase_156_I171G,beta-lactamase_156_171,TEM-1,beta-lactamase_156,P62593,1.01466,NO,171,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-2.431,-3.603,1.172,,0.361,,B,0.48,0.53,3.869,,77.62,HHO,-1.55533,0.111618,0.00623355,1.01466 beta-lactamase_2500_T112N,beta-lactamase_2500_112,TEM-1,beta-lactamase_2500,P62593,1.01466,NO,112,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.186,-2.739,0.553,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.361275,0.00531334,1.01466 beta-lactamase_625_N50I,beta-lactamase_625_50,TEM-1,beta-lactamase_625,P62593,1.01467,NO,50,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-2.979,-3.889,0.91,,0.912,T,A,0.61,1.24,3.446,,77.62,HPP,-2.134,0.213352,0.0047211,1.01467 beta-lactamase_625_Q86T,beta-lactamase_625_86,TEM-1,beta-lactamase_625,P62593,1.01467,NO,86,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.4,-2.587,0.187,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.213352,0.00450027,1.01467 beta-lactamase_K284D,beta-lactamase_284,TEM-1,beta-lactamase,P62593,1.01467,NO,284,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.981,-3.293,1.312,6.30084,0.848,H,A,1.82,0.67,1.931,,77.62,HBB,-1.82133,0.221079,0.0686156,1.01467 beta-lactamase_R176K,beta-lactamase_176,TEM-1,beta-lactamase,P62593,1.01467,NO,176,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-0.863,-2.782,1.919,5.61264,0.385,T,B,0.68,-0.63,,,,ABA,-1.38867,0.221079,0.00105554,1.01467 beta-lactamase_156_A182Q,beta-lactamase_156_182,TEM-1,beta-lactamase_156,P62593,1.01468,NO,182,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.777,-3.097,1.32,,0.136,H,A,0.46,-0.66,16.784,16.784,93.01,OHH,-1.27367,0.111618,0.00559099,1.01468 beta-lactamase_625_N274T,beta-lactamase_625_274,TEM-1,beta-lactamase_625,P62593,1.01468,NO,274,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.213352,0.0110418,1.01468 kka2_1:8_A65W,kka2_1:8_65,Kka2,kka2_1:8,P00552,1.01468,NO,65,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.744,-5.541,3.797,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.100394,0.00709258,1.01468 kka2_1:8_A65W,kka2_1:8_65,Kka2,kka2_1:8,P00552,1.01468,NO,65,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.744,-5.541,3.797,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.100394,0.00709258,1.01468 beta-lactamase_0_N50L,beta-lactamase_0_50,TEM-1,beta-lactamase_0,P62593,1.01469,NO,50,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-2.979,-2.892,-0.087,,0.912,T,A,0.61,1.24,9.874,9.874,77.62,HPP,-2.134,0.0500837,0.0047211,1.01469 beta-lactamase_39_S57G,beta-lactamase_39_57,TEM-1,beta-lactamase_39,P62593,1.01469,NO,57,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.918,-2.176,0.258,,0.352,E,B,0.27,-0.18,2.3,,72.73,APH,-2.29167,0.0495842,0.00492804,1.01469 beta-lactamase_625_L284A,beta-lactamase_625_284,TEM-1,beta-lactamase_625,P62593,1.01469,NO,284,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.213352,0.0686156,1.01469 beta-lactamase_39_G226F,beta-lactamase_39_226,TEM-1,beta-lactamase_39,P62593,1.0147,NO,226,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.461,-4.428,2.967,,0.701,T,l,0.29,-0.25,23.034,23.034,74.48,HOH,-1.42933,0.0495842,0.00665294,1.0147 kka2_1:2_D134H,kka2_1:2_134,Kka2,kka2_1:2,P00552,1.0147,NO,134,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.969,-4.532,3.563,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.295029,0.00270812,1.0147 beta-lactamase_156_L38C,beta-lactamase_156_38,TEM-1,beta-lactamase_156,P62593,1.01471,NO,38,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.343,-4.841,3.498,,0.088,H,A,0.55,0.2,13.556,13.556,64.34,PHO,-1.78033,0.111618,0.00373244,1.01471 beta-lactamase_2500_E26Q,beta-lactamase_2500_26,TEM-1,beta-lactamase_2500,P62593,1.01471,NO,26,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.454,-2.296,-0.158,,0.54,H,A,1.04,0.98,0.49,,93.01,OAP,-1.96167,0.361275,0.00297948,1.01471 beta-lactamase_39_K109L,beta-lactamase_39_109,TEM-1,beta-lactamase_39,P62593,1.01471,NO,109,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.734,-2.969,1.235,,0.787,G,A,2.34,2.21,7.243,,72.73,ABB,-1.63333,0.0495842,0.00462493,1.01471 beta-lactamase_625_I245C,beta-lactamase_625_245,TEM-1,beta-lactamase_625,P62593,1.01471,NO,245,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.213352,0.00391032,1.01471 beta-lactamase_L199L,beta-lactamase_199,TEM-1,beta-lactamase,P62593,1.01471,NO,199,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-2.942,-2.942,,5.57712,0.832,H,A,0.82,0.42,15.302,15.302,77.62,PHH,-2.32933,0.221079,0.0048649,1.01471 beta-lactamase_P12I,beta-lactamase_12,TEM-1,beta-lactamase,P62593,1.01471,NO,12,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-2.016,-2.714,0.698,,,,,,,2.88,,72.73,HOH,-2.05167,0.221079,0.00241653,1.01471 beta-lactamase_156_F58N,beta-lactamase_156_58,TEM-1,beta-lactamase_156,P62593,1.01472,NO,58,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-2.914,-3.795,0.881,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.111618,0.00523369,1.01472 beta-lactamase_156_L55Y,beta-lactamase_156_55,TEM-1,beta-lactamase_156,P62593,1.01472,NO,55,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.86,-3.812,1.952,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.111618,0.00403741,1.01472 beta-lactamase_156_M67V,beta-lactamase_156_67,TEM-1,beta-lactamase_156,P62593,1.01472,NO,67,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-2.231,-2.772,0.541,,0.006,G,P,0.55,-0.81,1.463,,65.03,HHP,-1.502,0.111618,0.00409753,1.01472 beta-lactamase_2500_A278K,beta-lactamase_2500_278,TEM-1,beta-lactamase_2500,P62593,1.01472,NO,278,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.361275,0.0310297,1.01472 beta-lactamase_0_A183S,beta-lactamase_0_183,TEM-1,beta-lactamase_0,P62593,1.01473,NO,183,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.231,-2.011,0.78,,0.155,H,A,0.46,-0.91,1.48,,77.62,HHH,-1.53367,0.0500837,0.00296631,1.01473 beta-lactamase_39_S241D,beta-lactamase_39_241,TEM-1,beta-lactamase_39,P62593,1.01473,NO,241,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.0495842,0.00452736,1.01473 beta-lactamase_625_E46Q,beta-lactamase_625_46,TEM-1,beta-lactamase_625,P62593,1.01473,NO,46,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.94,-4.007,2.067,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.213352,0.00427568,1.01473 PSD95pdz3_D357T,PSD95pdz3_357,PSD95pdz3,PSD95pdz3,P31016,1.01475,NO,357,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.264,-3.103,1.839,5.22306,,,,,10.975,,,,OAP,-1.32367,0.0758425,0.000609015,1.01475 beta-lactamase_156_H110R,beta-lactamase_156_110,TEM-1,beta-lactamase_156,P62593,1.01476,NO,110,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-1.706,-2.008,0.302,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.111618,0.00441499,1.01476 beta-lactamase_156_M67H,beta-lactamase_156_67,TEM-1,beta-lactamase_156,P62593,1.01476,NO,67,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-2.231,-4.763,2.532,,0.006,G,P,0.55,-0.81,1.463,,65.03,HHP,-1.502,0.111618,0.00409753,1.01476 beta-lactamase_2500_I171Y,beta-lactamase_2500_171,TEM-1,beta-lactamase_2500,P62593,1.01476,NO,171,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-2.431,-4.204,1.773,,0.361,,B,0.48,0.53,1.66,,77.62,HHO,-1.55533,0.361275,0.00623355,1.01476 beta-lactamase_156_S221T,beta-lactamase_156_221,TEM-1,beta-lactamase_156,P62593,1.01477,NO,221,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.754,-3.292,1.538,,0.624,H,A,0.27,-0.2,17.729,17.729,74.48,BPH,-1.59967,0.111618,0.0046094,1.01477 beta-lactamase_2500_S256E,beta-lactamase_2500_256,TEM-1,beta-lactamase_2500,P62593,1.01477,NO,256,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.361275,0.00710634,1.01477 beta-lactamase_0_D33T,beta-lactamase_0_33,TEM-1,beta-lactamase_0,P62593,1.01478,NO,33,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.321,-2.667,0.346,,0.366,H,A,0.75,0.33,12.514,12.514,77.62,BAH,-2.12133,0.0500837,0.00435556,1.01478 beta-lactamase_39_G265S,beta-lactamase_39_265,TEM-1,beta-lactamase_39,P62593,1.01478,NO,265,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-2.58,,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.0495842,0.00811926,1.01478 beta-lactamase_625_L191C,beta-lactamase_625_191,TEM-1,beta-lactamase_625,P62593,1.01478,NO,191,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.087,-4.696,3.609,,,H,A,0.55,0.09,1.908,,63.29,BHH,-1.445,0.213352,0.00263549,1.01478 beta-lactamase_2500_D36R,beta-lactamase_2500_36,TEM-1,beta-lactamase_2500,P62593,1.01479,NO,36,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.732,-2.847,0.115,,0.555,H,A,0.75,1.17,2.26,,77.62,AAP,-1.91167,0.361275,0.00476483,1.01479 beta-lactamase_625_E108S,beta-lactamase_625_108,TEM-1,beta-lactamase_625,P62593,1.01479,NO,108,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.46,-2.354,0.894,,0.572,G,A,1.04,1.87,20.151,20.151,72.73,PAB,-1.437,0.213352,0.00413372,1.01479 beta-lactamase_A266L,beta-lactamase_266,TEM-1,beta-lactamase,P62593,1.01479,NO,266,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.369,-2.659,1.29,5.02057,0.175,S,B,0.52,0.07,1.832,,64.34,PHP,-2.08567,0.221079,0.0140785,1.01479 beta-lactamase_Q204E,beta-lactamase_204,TEM-1,beta-lactamase,P62593,1.01479,NO,204,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-1.382,-3.106,1.724,5.46394,0.204,H,A,0.12,0.09,1.707,,66.08,PPH,-1.49067,0.221079,0.00364106,1.01479 beta-lactamase_Q86V,beta-lactamase_86,TEM-1,beta-lactamase,P62593,1.01479,NO,86,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.4,-2.988,0.588,5.39897,0.696,S,A,0.12,2.38,2.105,,77.62,OPA,-1.61067,0.221079,0.00450027,1.01479 beta-lactamase_39_D212H,beta-lactamase_39_212,TEM-1,beta-lactamase_39,P62593,1.0148,NO,212,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.624,-4.56,2.936,,0.037,,b,0.75,-0.58,10.748,10.748,74.48,HAB,-1.77667,0.0495842,0.00644302,1.0148 beta-lactamase_39_G154L,beta-lactamase_39_154,TEM-1,beta-lactamase_39,P62593,1.0148,NO,154,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.823,-3.779,2.956,,0.54,T,l,0.29,-0.56,1.151,,64.69,HOA,-1.635,0.0495842,0.00180205,1.0148 beta-lactamase_625_D231Q,beta-lactamase_625_231,TEM-1,beta-lactamase_625,P62593,1.0148,NO,231,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.816,-3.637,2.821,,,E,B,0.75,-1.06,1.025,,65.38,HAB,-0.994,0.213352,0.00107395,1.0148 beta-lactamase_625_E46T,beta-lactamase_625_46,TEM-1,beta-lactamase_625,P62593,1.01481,NO,46,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.94,-3.517,1.577,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.213352,0.00427568,1.01481 beta-lactamase_625_K53Y,beta-lactamase_625_53,TEM-1,beta-lactamase_625,P62593,1.01481,NO,53,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-2.313,-4.187,1.874,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.213352,0.00383383,1.01481 beta-lactamase_E61D,beta-lactamase_61,TEM-1,beta-lactamase,P62593,1.01481,NO,61,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.115,-1.402,-0.713,6.29701,0.775,T,a,0.52,1.29,1.975,,77.62,OAA,-1.92567,0.221079,0.00440955,1.01481 beta-lactamase_625_M127L,beta-lactamase_625_127,TEM-1,beta-lactamase_625,P62593,1.01482,NO,127,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-2.251,-2.123,-0.128,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.213352,0.00437927,1.01482 beta-lactamase_156_A84H,beta-lactamase_156_84,TEM-1,beta-lactamase_156,P62593,1.01483,NO,84,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.651,-3.344,1.693,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.111618,0.00503822,1.01483 beta-lactamase_156_L137F,beta-lactamase_156_137,TEM-1,beta-lactamase_156,P62593,1.01483,NO,137,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.03,-3.682,2.652,,,H,A,0.55,-0.38,0.674,,42.31,HHP,-1.58933,0.111618,0.00278599,1.01483 beta-lactamase_156_S80I,beta-lactamase_156_80,TEM-1,beta-lactamase_156,P62593,1.01483,NO,80,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.029,-3.787,1.758,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.111618,0.00565569,1.01483 beta-lactamase_39_L196Y,beta-lactamase_39_196,TEM-1,beta-lactamase_39,P62593,1.01483,NO,196,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-2.478,-4.286,1.808,,0.518,S,A,0.55,1.35,12.152,12.152,77.62,AHH,-1.839,0.0495842,0.00512144,1.01483 beta-lactamase_625_E238W,beta-lactamase_625_238,TEM-1,beta-lactamase_625,P62593,1.01484,NO,238,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.213352,0.00743256,1.01484 kka2_1:8_A14S,kka2_1:8_14,Kka2,kka2_1:8,P00552,1.01484,NO,14,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.837,-2.532,0.695,,0.728,G,A,0.46,0.7,,,71.59,HHH,-1.82567,0.100394,0.00706614,1.01484 kka2_1:8_A14S,kka2_1:8_14,Kka2,kka2_1:8,P00552,1.01484,NO,14,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.837,-2.532,0.695,,0.728,G,A,0.46,0.7,,,71.59,HHH,-1.82567,0.100394,0.00706614,1.01484 beta-lactamase_156_A215R,beta-lactamase_156_215,TEM-1,beta-lactamase_156,P62593,1.01485,NO,215,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.503,-3.862,2.359,,,,a,0.46,-0.93,3.583,,74.48,HHO,-1.42633,0.111618,0.00544007,1.01485 beta-lactamase_156_A230G,beta-lactamase_156_230,TEM-1,beta-lactamase_156,P62593,1.01485,NO,230,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.154,-1.479,0.325,,0.01,E,B,0.46,-1.17,2.179,,50,HHA,-1.079,0.111618,0.00516841,1.01485 beta-lactamase_156_K32W,beta-lactamase_156_32,TEM-1,beta-lactamase_156,P62593,1.01485,NO,32,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.984,-5.48,3.496,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.111618,0.00401283,1.01485 beta-lactamase_2500_S122D,beta-lactamase_2500_122,TEM-1,beta-lactamase_2500,P62593,1.01485,NO,122,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.406,-2.549,0.143,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.361275,0.00497825,1.01485 beta-lactamase_39_T138S,beta-lactamase_39_138,TEM-1,beta-lactamase_39,P62593,1.01485,NO,138,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.506,-2.455,-0.051,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.0495842,0.00487868,1.01485 beta-lactamase_625_K53D,beta-lactamase_625_53,TEM-1,beta-lactamase_625,P62593,1.01485,NO,53,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-2.313,-3.725,1.412,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.213352,0.00383383,1.01485 PSD95pdz3_F337W,PSD95pdz3_337,PSD95pdz3,PSD95pdz3,P31016,1.01485,NO,337,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.524,-4.104,2.58,5.22838,,,,,13.4936,,,,HHH,-1.59467,0.0758425,0.000875287,1.01485 beta-lactamase_156_A282W,beta-lactamase_156_282,TEM-1,beta-lactamase_156,P62593,1.01486,NO,282,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.111618,0.0449821,1.01486 beta-lactamase_39_A148Q,beta-lactamase_39_148,TEM-1,beta-lactamase_39,P62593,1.01486,NO,148,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.757,-3.083,1.326,,0.379,H,A,0.46,-0.55,3.551,,72.73,PHH,-1.40167,0.0495842,0.00547053,1.01486 beta-lactamase_156_E35A,beta-lactamase_156_35,TEM-1,beta-lactamase_156,P62593,1.01487,NO,35,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-0.869,-3.127,2.258,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.111618,0.00174441,1.01487 beta-lactamase_39_V72C,beta-lactamase_39_72,TEM-1,beta-lactamase_39,P62593,1.01487,NO,72,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.658,-4.8,3.142,,,H,A,0.44,-1.03,1.92,,65.73,BHH,-1.32167,0.0495842,0.00501194,1.01487 beta-lactamase_156_R273G,beta-lactamase_156_273,TEM-1,beta-lactamase_156,P62593,1.01488,NO,273,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.314,-2.465,0.151,,0.564,H,A,1.2,1.57,20.248,20.248,73.78,ABP,-1.841,0.111618,0.0077952,1.01488 beta-lactamase_2500_L28V,beta-lactamase_2500_28,TEM-1,beta-lactamase_2500,P62593,1.01488,NO,28,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.579,-1.979,0.4,,0.277,H,A,0.55,-0.16,2.716,,93.01,PHH,-2.11333,0.361275,0.00359321,1.01488 beta-lactamase_39_H151S,beta-lactamase_39_151,TEM-1,beta-lactamase_39,P62593,1.01489,NO,151,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-2.96,-2.636,-0.324,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.0495842,0.00216946,1.01489 beta-lactamase_625_V29R,beta-lactamase_625_29,TEM-1,beta-lactamase_625,P62593,1.01489,NO,29,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-2.856,-3.682,0.826,,0.733,H,A,0.44,-0.78,1.931,,93.01,HHB,-2.24733,0.213352,0.00318969,1.01489 beta-lactamase_156_D212V,beta-lactamase_156_212,TEM-1,beta-lactamase_156,P62593,1.0149,NO,212,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.624,-3.608,1.984,,0.037,,b,0.75,-0.58,20.222,20.222,74.48,HAB,-1.77667,0.111618,0.00644302,1.0149 beta-lactamase_156_E279V,beta-lactamase_156_279,TEM-1,beta-lactamase_156,P62593,1.0149,NO,279,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.111618,0.0192826,1.0149 beta-lactamase_156_V31I,beta-lactamase_156_31,TEM-1,beta-lactamase_156,P62593,1.0149,NO,31,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.822,-1.838,0.016,,,H,A,0.44,-0.46,4.126,,73.78,BHB,-2.03767,0.111618,0.00478065,1.0149 gb1_A274D,gb1_274,gb1,gb1,P06654,1.0149,NO,274,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.728,-1.983,0.255,,,,,,,4.162,4.162,11.83,AHP,-1.81767,0.177985,0.0068419,1.0149 gb1_N234Q,gb1_234,gb1,gb1,P06654,1.0149,NO,234,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-2.055,-3.349,1.294,,,,,,,1.235,,45.54,HPO,-2.05067,0.177985,0.00242189,1.0149 beta-lactamase_156_N50K,beta-lactamase_156_50,TEM-1,beta-lactamase_156,P62593,1.01491,NO,50,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-2.979,-3.578,0.599,,0.912,T,A,0.61,1.24,13.295,13.295,77.62,HPP,-2.134,0.111618,0.0047211,1.01491 beta-lactamase_39_E279T,beta-lactamase_39_279,TEM-1,beta-lactamase_39,P62593,1.01491,NO,279,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.0495842,0.0192826,1.01491 beta-lactamase_D36V,beta-lactamase_36,TEM-1,beta-lactamase,P62593,1.01491,NO,36,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.732,-3.726,0.994,5.39764,0.555,H,A,0.11,1.17,13.689,13.689,77.62,AAP,-1.91167,0.221079,0.00476483,1.01491 beta-lactamase_E195H,beta-lactamase_195,TEM-1,beta-lactamase,P62593,1.01491,NO,195,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.186,-3.381,1.195,7.28489,1.016,S,A,1.52,0.85,2.583,,77.62,OAH,-2.02,0.221079,0.00496565,1.01491 beta-lactamase_E210V,beta-lactamase_210,TEM-1,beta-lactamase,P62593,1.01491,NO,210,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.319,-1.881,-0.438,5.7398,0.476,H,A,0.52,0.75,1.555,,77.62,HAH,-1.88567,0.221079,0.00663582,1.01491 beta-lactamase_E26L,beta-lactamase_26,TEM-1,beta-lactamase,P62593,1.01491,NO,26,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.454,-2.726,0.272,,0.54,H,A,1.04,0.98,,,93.01,OAP,-1.96167,0.221079,0.00297948,1.01491 beta-lactamase_N50P,beta-lactamase_50,TEM-1,beta-lactamase,P62593,1.01491,NO,50,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-2.979,-3.95,0.971,5.51261,0.912,T,A,1.07,1.24,1.581,,77.62,HPP,-2.134,0.221079,0.0047211,1.01491 beta-lactamase_S254C,beta-lactamase_254,TEM-1,beta-lactamase,P62593,1.01491,NO,254,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.126,-5.051,2.925,5.49575,0.312,,a,0.25,-0.48,24.91,24.91,69.58,OPB,-2.215,0.221079,0.00369,1.01491 beta-lactamase_T27V,beta-lactamase_27,TEM-1,beta-lactamase,P62593,1.01491,NO,27,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.905,-3.409,1.504,5.39752,0.007,H,A,0.69,-0.37,0.745,,93.01,APH,-1.97933,0.221079,0.00306559,1.01491 beta-lactamase_R238C,beta-lactamase_238,TEM-1,beta-lactamase,P62593,1.01492,NO,238,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.002,-5.167,3.165,5.87663,0.564,T,L,0.45,1.09,4.195,,72.73,ABO,-1.62633,0.221079,0.00743256,1.01492 beta-lactamase_39_E61K,beta-lactamase_39_61,TEM-1,beta-lactamase_39,P62593,1.01494,NO,61,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.115,-3.46,1.345,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.0495842,0.00440955,1.01494 beta-lactamase_625_L100I,beta-lactamase_625_100,TEM-1,beta-lactamase_625,P62593,1.01494,NO,100,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.218,-1.863,0.645,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.213352,0.00413885,1.01494 beta-lactamase_156_I140V,beta-lactamase_156_140,TEM-1,beta-lactamase_156,P62593,1.01495,NO,140,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.733,-1.662,-0.071,,0.128,H,A,0.48,0.41,1.16,,73.08,PHO,-1.48733,0.111618,0.00597777,1.01495 beta-lactamase_156_L284Q,beta-lactamase_156_284,TEM-1,beta-lactamase_156,P62593,1.01495,NO,284,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.111618,0.0686156,1.01495 beta-lactamase_625_T193R,beta-lactamase_625_193,TEM-1,beta-lactamase_625,P62593,1.01495,NO,193,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.914,-4.014,2.1,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.213352,0.00482669,1.01495 beta-lactamase_156_W208L,beta-lactamase_156_208,TEM-1,beta-lactamase_156,P62593,1.01496,NO,208,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-0.818,-3.358,2.54,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.111618,0.00126609,1.01496 beta-lactamase_39_R63A,beta-lactamase_39_63,TEM-1,beta-lactamase_39,P62593,1.01496,NO,63,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-0.943,-3.103,2.16,,0.218,,B,1.2,-0.31,0.326,,44.06,ABH,-0.992333,0.0495842,0.00126938,1.01496 beta-lactamase_156_Q37D,beta-lactamase_156_37,TEM-1,beta-lactamase_156,P62593,1.01498,NO,37,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.134,-2.904,0.77,,0.613,H,A,0.64,1.98,12.052,12.052,73.08,APH,-2.06967,0.111618,0.00425833,1.01498 beta-lactamase_2500_A247L,beta-lactamase_2500_247,TEM-1,beta-lactamase_2500,P62593,1.01498,NO,247,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.48,-2.56,1.08,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.361275,0.00611275,1.01498 beta-lactamase_39_V259Y,beta-lactamase_39_259,TEM-1,beta-lactamase_39,P62593,1.01498,NO,259,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.0495842,0.0070773,1.01498 beta-lactamase_A182K,beta-lactamase_182,TEM-1,beta-lactamase,P62593,1.01498,NO,182,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.777,-2.859,1.082,4.98609,0.136,H,A,0.52,-0.66,2.032,,93.01,OHH,-1.27367,0.221079,0.00559099,1.01498 beta-lactamase_0_T263V,beta-lactamase_0_263,TEM-1,beta-lactamase_0,P62593,1.015,NO,263,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.0500837,0.0110582,1.015 beta-lactamase_2500_E119D,beta-lactamase_2500_119,TEM-1,beta-lactamase_2500,P62593,1.015,NO,119,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.412,-2.093,0.681,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.361275,0.00386966,1.015 beta-lactamase_625_D36C,beta-lactamase_625_36,TEM-1,beta-lactamase_625,P62593,1.015,NO,36,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.732,-5.131,2.399,,0.555,H,A,0.75,1.17,2.26,,77.62,AAP,-1.91167,0.213352,0.00476483,1.015 beta-lactamase_156_L55W,beta-lactamase_156_55,TEM-1,beta-lactamase_156,P62593,1.01501,NO,55,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.86,-2.099,0.239,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.111618,0.00403741,1.01501 beta-lactamase_156_S256C,beta-lactamase_156_256,TEM-1,beta-lactamase_156,P62593,1.01501,NO,256,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.111618,0.00710634,1.01501 kka2_1:8_G164F,kka2_1:8_164,Kka2,kka2_1:8,P00552,1.01501,NO,164,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.869,-4.375,3.506,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.100394,0.00442091,1.01501 kka2_1:8_G164F,kka2_1:8_164,Kka2,kka2_1:8,P00552,1.01501,NO,164,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.869,-4.375,3.506,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.100394,0.00442091,1.01501 beta-lactamase_625_S256K,beta-lactamase_625_256,TEM-1,beta-lactamase_625,P62593,1.01502,NO,256,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.213352,0.00710634,1.01502 beta-lactamase_S281T,beta-lactamase_281,TEM-1,beta-lactamase,P62593,1.01502,NO,281,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.247,-2.247,0,4.73591,0.128,H,A,0.25,-0.26,2.144,,77.62,HPH,-1.847,0.221079,0.0406482,1.01502 PSD95pdz3_G333Y,PSD95pdz3_333,PSD95pdz3,PSD95pdz3,P31016,1.01502,NO,333,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.008,-4.069,3.061,5.09445,,,,,48.755,,,,AOA,-1.22533,0.0758425,0.00092544,1.01502 beta-lactamase_39_I93C,beta-lactamase_39_93,TEM-1,beta-lactamase_39,P62593,1.01503,NO,93,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.401,-4.797,3.396,,0.128,E,B,0.48,0.44,1.757,,67.83,BHB,-1.873,0.0495842,0.00527066,1.01503 beta-lactamase_625_A84V,beta-lactamase_625_84,TEM-1,beta-lactamase_625,P62593,1.01503,NO,84,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.651,-2.943,1.292,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.213352,0.00503822,1.01503 E1_Ubiquitin_A46F,E1_Ubiquitin_46,Uba1,E1_Ubiquitin,P0CG63,1.01503,NO,46,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.367,-3.958,2.591,,0.398,T,L,,-0.8,,,,HHO,-1.17167,0.18783,0.004233,1.01503 E1_Ubiquitin_F45S,E1_Ubiquitin_45,Uba1,E1_Ubiquitin,P0CG63,1.01503,NO,45,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.149,-3.428,2.279,,0.26,E,B,,-0.99,,,,HHH,-1.316,0.18783,0.00193245,1.01503 E1_Ubiquitin_H70V,E1_Ubiquitin_70,Uba1,E1_Ubiquitin,P0CG63,1.01503,NO,70,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-1.36,-4.724,3.364,,0.05,E,B,0.61,-0.97,,,93.18,HBH,-1.146,0.18783,0.00206914,1.01503 E1_Ubiquitin_I44T,E1_Ubiquitin_44,Uba1,E1_Ubiquitin,P0CG63,1.01503,NO,44,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.432,-3.324,1.892,,,E,B,0.27,-1.17,4.57,,78.74,HHH,-1.25633,0.18783,0.00209731,1.01503 E1_Ubiquitin_L43M,E1_Ubiquitin_43,Uba1,E1_Ubiquitin,P0CG63,1.01503,NO,43,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.188,-3.803,2.615,,,E,B,,-1.17,,,,BHH,-1.30733,0.18783,0.00190185,1.01503 E1_Ubiquitin_Q41D,E1_Ubiquitin_41,Uba1,E1_Ubiquitin,P0CG63,1.01503,NO,41,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-1.25,-3.061,1.811,,0.017,E,B,,-0.98,,,,PPB,-1.344,0.18783,0.00215097,1.01503 E1_Ubiquitin_R74F,E1_Ubiquitin_74,Uba1,E1_Ubiquitin,P0CG63,1.01503,NO,74,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.302,-4.162,2.86,,0.838,T,A,,3.15,,,,HBO,-1.11333,0.18783,0.00180798,1.01503 E1_Ubiquitin_R74L,E1_Ubiquitin_74,Uba1,E1_Ubiquitin,P0CG63,1.01503,NO,74,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.302,-3.229,1.927,,0.838,T,A,,3.15,,,,HBO,-1.11333,0.18783,0.00180798,1.01503 E1_Ubiquitin_R74M,E1_Ubiquitin_74,Uba1,E1_Ubiquitin,P0CG63,1.01503,NO,74,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.302,-4.35,3.048,,0.838,T,A,,3.15,,,,HBO,-1.11333,0.18783,0.00180798,1.01503 E1_Ubiquitin_R74N,E1_Ubiquitin_74,Uba1,E1_Ubiquitin,P0CG63,1.01503,NO,74,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.302,-3.318,2.016,,0.838,T,A,,3.15,,,,HBO,-1.11333,0.18783,0.00180798,1.01503 beta-lactamase_156_F58I,beta-lactamase_156_58,TEM-1,beta-lactamase_156,P62593,1.01504,NO,58,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-2.914,-3.971,1.057,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.111618,0.00523369,1.01504 beta-lactamase_39_A84W,beta-lactamase_39_84,TEM-1,beta-lactamase_39,P62593,1.01504,NO,84,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.651,-5.52,3.869,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.0495842,0.00503822,1.01504 beta-lactamase_39_R59H,beta-lactamase_39_59,TEM-1,beta-lactamase_39,P62593,1.01504,NO,59,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.345,-4.424,3.079,,0.329,S,L,1.2,-0.09,1.806,,73.08,HBO,-2.24267,0.0495842,0.00318082,1.01504 beta-lactamase_625_A183R,beta-lactamase_625_183,TEM-1,beta-lactamase_625,P62593,1.01504,NO,183,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.231,-3.825,2.594,,0.155,H,A,0.46,-0.91,23.859,23.859,77.62,HHH,-1.53367,0.213352,0.00296631,1.01504 beta-lactamase_R92R,beta-lactamase_92,TEM-1,beta-lactamase,P62593,1.01504,NO,92,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.718,-1.718,,5.65832,0.479,E,B,0.91,1.36,3.069,,65.38,BBH,-1.50367,0.221079,0.00429626,1.01504 beta-lactamase_156_T27S,beta-lactamase_156_27,TEM-1,beta-lactamase_156,P62593,1.01505,NO,27,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.905,-2.606,0.701,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.111618,0.00306559,1.01505 beta-lactamase_39_L47F,beta-lactamase_39_47,TEM-1,beta-lactamase_39,P62593,1.01505,NO,47,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.876,-3.101,1.225,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.0495842,0.00439844,1.01505 beta-lactamase_39_K190V,beta-lactamase_39_190,TEM-1,beta-lactamase_39,P62593,1.01506,NO,190,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.994,-2.992,0.998,,0.371,H,A,2.34,0.16,1.513,,77.62,BBH,-1.64167,0.0495842,0.00574527,1.01506 beta-lactamase_156_E35I,beta-lactamase_156_35,TEM-1,beta-lactamase_156,P62593,1.01507,NO,35,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-0.869,-4.036,3.167,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.111618,0.00174441,1.01507 beta-lactamase_E175T,beta-lactamase_175,TEM-1,beta-lactamase,P62593,1.01507,NO,175,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.336,-3.551,1.215,6.0311,0.551,,A,0.75,1.05,5.316,,77.62,AAB,-1.31233,0.221079,0.00482205,1.01507 beta-lactamase_N98S,beta-lactamase_98,TEM-1,beta-lactamase,P62593,1.01507,NO,98,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-2.973,-2.34,-0.633,6.59973,0.963,G,A,1.07,1.35,1.332,,77.62,PPA,-2.07867,0.221079,0.00505389,1.01507 beta-lactamase_156_L150T,beta-lactamase_156_150,TEM-1,beta-lactamase_156,P62593,1.01508,NO,150,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.326,-2.5,1.174,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.111618,0.00463171,1.01508 beta-lactamase_156_P165H,beta-lactamase_156_165,TEM-1,beta-lactamase_156,P62593,1.01508,NO,165,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.373,-4.751,3.378,,0.203,T,A,0.52,-0.31,3.907,,73.78,AOA,-1.359,0.111618,0.00549538,1.01508 beta-lactamase_K284T,beta-lactamase_284,TEM-1,beta-lactamase,P62593,1.01508,NO,284,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.981,-2.647,0.666,6.30084,0.848,H,A,1.82,0.67,1.931,,77.62,HBB,-1.82133,0.221079,0.0686156,1.01508 beta-lactamase_0_E87D,beta-lactamase_0_87,TEM-1,beta-lactamase_0,P62593,1.01509,NO,87,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.421,-2.265,0.844,,0.048,,B,1.04,0.92,1.159,,64.69,PAP,-1.969,0.0500837,0.00337888,1.01509 beta-lactamase_2500_V29E,beta-lactamase_2500_29,TEM-1,beta-lactamase_2500,P62593,1.01509,NO,29,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-2.856,-1.855,-1.001,,0.733,H,A,0.44,-0.78,1.931,,93.01,HHB,-2.24733,0.361275,0.00318969,1.01509 beta-lactamase_39_K190P,beta-lactamase_39_190,TEM-1,beta-lactamase_39,P62593,1.01509,NO,190,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.994,-3.086,1.092,,0.371,H,A,2.34,0.16,1.513,,77.62,BBH,-1.64167,0.0495842,0.00574527,1.01509 beta-lactamase_625_A84R,beta-lactamase_625_84,TEM-1,beta-lactamase_625,P62593,1.01509,NO,84,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.651,-2.603,0.952,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.213352,0.00503822,1.01509 kka2_1:8_A56N,kka2_1:8_56,Kka2,kka2_1:8,P00552,1.01509,NO,56,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.083,-3.917,1.834,,0.796,T,A,0.46,1.39,10.511,,71.59,OHH,-1.86867,0.100394,0.00717715,1.01509 kka2_1:8_A56N,kka2_1:8_56,Kka2,kka2_1:8,P00552,1.01509,NO,56,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.083,-3.917,1.834,,0.796,T,A,0.46,1.39,10.511,,71.59,OHH,-1.86867,0.100394,0.00717715,1.01509 beta-lactamase_39_I244Y,beta-lactamase_39_244,TEM-1,beta-lactamase_39,P62593,1.0151,NO,244,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.555,-4.031,2.476,,,E,B,0.48,-0.84,1.325,,77.62,OHH,-1.385,0.0495842,0.00605379,1.0151 beta-lactamase_39_T69G,beta-lactamase_39_69,TEM-1,beta-lactamase_39,P62593,1.0151,NO,69,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-0.973,-3.289,2.316,,,G,A,0.22,-1.24,4.194,,93.01,PPH,-1.01833,0.0495842,0.00127498,1.0151 beta-lactamase_156_G141Y,beta-lactamase_156_141,TEM-1,beta-lactamase_156,P62593,1.01511,NO,141,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.828,-4.424,3.596,,0.575,T,l,0.29,-0.28,0.198,,64.69,HOO,-1.08933,0.111618,0.0012419,1.01511 beta-lactamase_H156D,beta-lactamase_156,TEM-1,beta-lactamase,P62593,1.01511,NO,156,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-3.156,-2.458,-0.698,6.00284,0.753,S,A,0.72,-0.6,6.456,6.456,77.62,ABH,-1.932,0.221079,0.00468596,1.01511 beta-lactamase_V29A,beta-lactamase_29,TEM-1,beta-lactamase,P62593,1.01511,NO,29,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-2.856,-2.61,-0.246,5.58481,0.733,H,A,0.23,-0.78,1.287,,93.01,HHB,-2.24733,0.221079,0.00318969,1.01511 beta-lactamase_0_R273T,beta-lactamase_0_273,TEM-1,beta-lactamase_0,P62593,1.01512,NO,273,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.314,-3.558,1.244,,0.564,H,A,1.2,1.57,20.248,20.248,73.78,ABP,-1.841,0.0500837,0.0077952,1.01512 beta-lactamase_Q203R,beta-lactamase_203,TEM-1,beta-lactamase,P62593,1.01512,NO,203,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.168,-2.451,0.283,5.65296,0.47,H,A,0.12,-0.38,1.66,,65.38,BPP,-1.614,0.221079,0.00631514,1.01512 beta-lactamase_2500_I93V,beta-lactamase_2500_93,TEM-1,beta-lactamase_2500,P62593,1.01513,NO,93,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.401,-1.692,0.291,,0.128,E,B,0.48,0.44,19.374,19.374,67.83,BHB,-1.873,0.361275,0.00527066,1.01513 beta-lactamase_2500_L111I,beta-lactamase_2500_111,TEM-1,beta-lactamase_2500,P62593,1.01516,NO,111,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.76,-2.153,0.393,,0.328,T,A,0.55,0.93,1.966,,64.34,BHP,-1.884,0.361275,0.00480671,1.01516 beta-lactamase_39_E166R,beta-lactamase_39_166,TEM-1,beta-lactamase_39,P62593,1.01516,NO,166,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.756,-3.805,2.049,,0.508,G,A,1.04,1.05,17.227,17.227,73.08,OAH,-1.42233,0.0495842,0.00512989,1.01516 beta-lactamase_39_K190I,beta-lactamase_39_190,TEM-1,beta-lactamase_39,P62593,1.01516,NO,190,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.994,-3.984,1.99,,0.371,H,A,2.34,0.16,1.513,,77.62,BBH,-1.64167,0.0495842,0.00574527,1.01516 beta-lactamase_625_L100T,beta-lactamase_625_100,TEM-1,beta-lactamase_625,P62593,1.01516,NO,100,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.218,-3.502,2.284,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.213352,0.00413885,1.01516 beta-lactamase_625_Q86H,beta-lactamase_625_86,TEM-1,beta-lactamase_625,P62593,1.01516,NO,86,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.4,-4.718,2.318,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.213352,0.00450027,1.01516 beta-lactamase_E166F,beta-lactamase_166,TEM-1,beta-lactamase,P62593,1.01517,NO,166,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.756,-4.345,2.589,5.60527,0.508,G,A,0.52,1.05,2.124,,73.08,OAH,-1.42233,0.221079,0.00512989,1.01517 beta-lactamase_N152S,beta-lactamase_152,TEM-1,beta-lactamase,P62593,1.01517,NO,152,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-2.757,-1.988,-0.769,5.98571,0.863,H,A,0.09,0.92,2.061,,77.62,BPH,-2.97,0.221079,0.00471429,1.01517 kka2_1:2_S54I,kka2_1:2_54,Kka2,kka2_1:2,P00552,1.01517,NO,54,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.471,-2.562,0.091,,0.408,S,b,0.27,1.01,0.393,,71.59,HPO,-2.259,0.295029,0.00782867,1.01517 kka2_1:4_S40L,kka2_1:4_40,Kka2,kka2_1:4,P00552,1.01517,NO,40,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.645,-3.085,0.44,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.168804,0.00693477,1.01517 beta-lactamase_156_A133C,beta-lactamase_156_133,TEM-1,beta-lactamase_156,P62593,1.01518,NO,133,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.186,-4.706,3.52,,,H,A,0.46,-0.86,0.805,,67.83,HHP,-0.988333,0.111618,0.00468022,1.01518 kka2_1:4_W236M,kka2_1:4_236,Kka2,kka2_1:4,P00552,1.01518,NO,236,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-1.363,-4.508,3.145,,0.303,H,A,0.47,-0.76,2.277,,48.48,AHH,-1.81267,0.168804,0.0088796,1.01518 beta-lactamase_156_A77E,beta-lactamase_156_77,TEM-1,beta-lactamase_156,P62593,1.0152,NO,77,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.234,-3.61,2.376,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.111618,0.00282362,1.0152 beta-lactamase_156_R92V,beta-lactamase_156_92,TEM-1,beta-lactamase_156,P62593,1.0152,NO,92,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.718,-2.509,0.791,,0.479,E,B,1.2,1.36,19.112,19.112,65.38,BBH,-1.50367,0.111618,0.00429626,1.0152 beta-lactamase_39_R91G,beta-lactamase_39_91,TEM-1,beta-lactamase_39,P62593,1.0152,NO,91,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.392,-3.437,2.045,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.0495842,0.00380226,1.0152 beta-lactamase_625_R239I,beta-lactamase_625_239,TEM-1,beta-lactamase_625,P62593,1.0152,NO,239,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.213352,0.00213852,1.0152 beta-lactamase_156_T186Y,beta-lactamase_156_186,TEM-1,beta-lactamase_156,P62593,1.01521,NO,186,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.522,-4.364,1.842,,0.396,H,A,0.22,-0.28,16.606,16.606,77.62,HPP,-1.77633,0.111618,0.00485034,1.01521 beta-lactamase_39_R159M,beta-lactamase_39_159,TEM-1,beta-lactamase_39,P62593,1.01521,NO,159,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-0.94,-4.529,3.589,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.0495842,0.00108472,1.01521 beta-lactamase_0_K213R,beta-lactamase_0_213,TEM-1,beta-lactamase_0,P62593,1.01522,NO,213,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.81,-1.968,0.158,,0.67,,A,2.34,0.29,3.015,,67.83,ABH,-1.57767,0.0500837,0.00610411,1.01522 beta-lactamase_39_L49A,beta-lactamase_39_49,TEM-1,beta-lactamase_39,P62593,1.01522,NO,49,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.897,-3.125,1.228,,0.131,T,A,0.55,0.04,13.838,13.838,64.69,AHP,-1.99233,0.0495842,0.00401477,1.01522 beta-lactamase_625_M127R,beta-lactamase_625_127,TEM-1,beta-lactamase_625,P62593,1.01522,NO,127,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-2.251,-2.722,0.471,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.213352,0.00437927,1.01522 beta-lactamase_156_F149G,beta-lactamase_156_149,TEM-1,beta-lactamase_156,P62593,1.01524,NO,149,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.299,-3.587,2.288,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.111618,0.00418462,1.01524 beta-lactamase_2500_V29N,beta-lactamase_2500_29,TEM-1,beta-lactamase_2500,P62593,1.01524,NO,29,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-2.856,-2.832,-0.024,,0.733,H,A,0.44,-0.78,1.931,,93.01,HHB,-2.24733,0.361275,0.00318969,1.01524 beta-lactamase_156_K109L,beta-lactamase_156_109,TEM-1,beta-lactamase_156,P62593,1.01526,NO,109,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.734,-2.969,1.235,,0.787,G,A,2.34,2.21,6.031,,72.73,ABB,-1.63333,0.111618,0.00462493,1.01526 beta-lactamase_156_L197E,beta-lactamase_156_197,TEM-1,beta-lactamase_156,P62593,1.01526,NO,197,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.853,-3.853,3,,0.007,S,B,0.55,0.33,1.58,,60.14,HHP,-1.833,0.111618,0.00144602,1.01526 beta-lactamase_0_L73P,beta-lactamase_0_73,TEM-1,beta-lactamase_0,P62593,1.01527,NO,73,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.507,-2.751,1.244,,,H,A,0.55,-0.64,0.877,,67.83,HHH,-1.487,0.0500837,0.00488983,1.01527 beta-lactamase_156_F70G,beta-lactamase_156_70,TEM-1,beta-lactamase_156,P62593,1.01527,NO,70,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.169,-3.574,2.405,,,H,A,0.58,-1.34,1.918,,63.99,PHB,-0.980667,0.111618,0.00193499,1.01527 beta-lactamase_156_I285A,beta-lactamase_156_285,TEM-1,beta-lactamase_156,P62593,1.01527,NO,285,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.111618,0.101555,1.01527 beta-lactamase_39_R162K,beta-lactamase_39_162,TEM-1,beta-lactamase_39,P62593,1.01527,NO,162,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.016,-2.948,1.932,,0.124,S,B,1.2,-0.37,31.656,31.656,64.69,ABH,-1.25,0.0495842,0.000561334,1.01527 beta-lactamase_625_F58Q,beta-lactamase_625_58,TEM-1,beta-lactamase_625,P62593,1.01527,NO,58,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-2.914,-2.803,-0.111,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.213352,0.00523369,1.01527 beta-lactamase_156_E272A,beta-lactamase_156_272,TEM-1,beta-lactamase_156,P62593,1.01528,NO,272,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.111618,0.00545371,1.01528 beta-lactamase_2500_E61K,beta-lactamase_2500_61,TEM-1,beta-lactamase_2500,P62593,1.01528,NO,61,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.115,-3.46,1.345,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.361275,0.00440955,1.01528 beta-lactamase_39_E166T,beta-lactamase_39_166,TEM-1,beta-lactamase_39,P62593,1.01528,NO,166,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.756,-2.857,1.101,,0.508,G,A,1.04,1.05,17.227,17.227,73.08,OAH,-1.42233,0.0495842,0.00512989,1.01528 beta-lactamase_2500_N50M,beta-lactamase_2500_50,TEM-1,beta-lactamase_2500,P62593,1.01529,NO,50,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-2.979,-4.727,1.748,,0.912,T,A,0.61,1.24,1.581,,77.62,HPP,-2.134,0.361275,0.0047211,1.01529 beta-lactamase_39_F70C,beta-lactamase_39_70,TEM-1,beta-lactamase_39,P62593,1.01529,NO,70,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.169,-4.871,3.702,,,H,A,0.58,-1.34,1.14,,63.99,PHB,-0.980667,0.0495842,0.00193499,1.01529 beta-lactamase_39_T126W,beta-lactamase_39_126,TEM-1,beta-lactamase_39,P62593,1.01529,NO,126,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.122,-5.243,4.121,,0.05,H,A,0.22,-0.05,0.586,,44.41,HPH,-1.60467,0.0495842,0.00244552,1.01529 beta-lactamase_625_I280L,beta-lactamase_625_280,TEM-1,beta-lactamase_625,P62593,1.01529,NO,280,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.213352,0.0530888,1.01529 beta-lactamase_A280I,beta-lactamase_280,TEM-1,beta-lactamase,P62593,1.01529,NO,280,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.708,-4.017,2.309,4.74932,0.379,H,A,0.52,-0.72,1.785,,68.18,OHP,-1.66433,0.221079,0.0530888,1.01529 beta-lactamase_D250H,beta-lactamase_250,TEM-1,beta-lactamase,P62593,1.01529,NO,250,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.335,-3.344,1.009,5.72026,0.89,T,L,0.23,1.53,24.737,24.737,66.08,OAO,-1.85133,0.221079,0.00550899,1.01529 beta-lactamase_L49F,beta-lactamase_49,TEM-1,beta-lactamase,P62593,1.01529,NO,49,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.897,-3.092,1.195,5.86005,0.131,T,A,1.3,0.04,3.112,,64.69,AHP,-1.99233,0.221079,0.00401477,1.01529 beta-lactamase_Q203H,beta-lactamase_203,TEM-1,beta-lactamase,P62593,1.01529,NO,203,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.168,-4.663,2.495,5.65296,0.47,H,A,0.12,-0.38,1.66,,65.38,BPP,-1.614,0.221079,0.00631514,1.01529 kka2_1:8_Q219C,kka2_1:8_219,Kka2,kka2_1:8,P00552,1.01529,NO,219,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-0.93,-5.139,4.209,,0.088,H,A,0.4,-0.85,0.897,,50,HPA,-1.05167,0.100394,0.00237913,1.01529 kka2_1:8_Q219C,kka2_1:8_219,Kka2,kka2_1:8,P00552,1.01529,NO,219,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-0.93,-5.139,4.209,,0.088,H,A,0.4,-0.85,0.897,,50,HPA,-1.05167,0.100394,0.00237913,1.01529 Pab1_E174N,Pab1_174,Pab1,Pab1,P04147,1.01529,NO,174,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.422,-3.356,1.934,,0.578,S,A,,0.38,,,,HAA,-1.65133,0.175299,0.00077863,1.01529 beta-lactamase_39_R273E,beta-lactamase_39_273,TEM-1,beta-lactamase_39,P62593,1.0153,NO,273,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.314,-2.209,-0.105,,0.564,H,A,1.2,1.57,2.163,,73.78,ABP,-1.841,0.0495842,0.0077952,1.0153 beta-lactamase_156_L28Y,beta-lactamase_156_28,TEM-1,beta-lactamase_156,P62593,1.01531,NO,28,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.579,-4.094,2.515,,0.277,H,A,0.55,-0.16,3.262,,93.01,PHH,-2.11333,0.111618,0.00359321,1.01531 beta-lactamase_39_G194E,beta-lactamase_39_194,TEM-1,beta-lactamase_39,P62593,1.01531,NO,194,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.396,-2.361,0.965,,0.276,S,b,0.29,0.36,4.852,,67.83,POA,-1.832,0.0495842,0.00392163,1.01531 beta-lactamase_39_G52Q,beta-lactamase_39_52,TEM-1,beta-lactamase_39,P62593,1.01531,NO,52,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.149,-2.995,1.846,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.0495842,0.00340138,1.01531 beta-lactamase_625_A84N,beta-lactamase_625_84,TEM-1,beta-lactamase_625,P62593,1.01531,NO,84,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.651,-2.768,1.117,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.213352,0.00503822,1.01531 beta-lactamase_156_G52D,beta-lactamase_156_52,TEM-1,beta-lactamase_156,P62593,1.01532,NO,52,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.149,-2.123,0.974,,0.299,,l,0.29,-0.04,1.179,,64.69,POB,-1.66267,0.111618,0.00340138,1.01532 beta-lactamase_625_A84Q,beta-lactamase_625_84,TEM-1,beta-lactamase_625,P62593,1.01532,NO,84,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.651,-2.658,1.007,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.213352,0.00503822,1.01532 beta-lactamase_625_R118N,beta-lactamase_625_118,TEM-1,beta-lactamase_625,P62593,1.01532,NO,118,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.413,-3.711,1.298,,0.457,H,A,1.2,1.39,2.144,,77.62,HBA,-1.785,0.213352,0.00538794,1.01532 beta-lactamase_39_N274K,beta-lactamase_39_274,TEM-1,beta-lactamase_39,P62593,1.01533,NO,274,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.0495842,0.0110418,1.01533 beta-lactamase_39_P224C,beta-lactamase_39_224,TEM-1,beta-lactamase_39,P62593,1.01533,NO,224,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.893,-5.08,4.187,,0.383,,B,0.52,-0.3,3.169,,74.48,HOH,-1.26433,0.0495842,0.00189564,1.01533 beta-lactamase_39_E238N,beta-lactamase_39_238,TEM-1,beta-lactamase_39,P62593,1.01534,NO,238,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.0495842,0.00743256,1.01534 beta-lactamase_K144G,beta-lactamase_144,TEM-1,beta-lactamase,P62593,1.01534,NO,144,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-2.388,-2.818,0.43,6.02507,0.863,H,A,2.81,1.27,0.515,,77.62,OBA,-1.904,0.221079,0.00481141,1.01534 beta-lactamase_625_A282F,beta-lactamase_625_282,TEM-1,beta-lactamase_625,P62593,1.01535,NO,282,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.213352,0.0449821,1.01535 beta-lactamase_625_K30Q,beta-lactamase_625_30,TEM-1,beta-lactamase_625,P62593,1.01536,NO,30,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-2.307,-2.158,-0.149,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.213352,0.00448593,1.01536 beta-lactamase_156_S201K,beta-lactamase_156_201,TEM-1,beta-lactamase_156,P62593,1.01538,NO,201,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.183,-3.387,2.204,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.111618,0.00198815,1.01538 beta-lactamase_39_K109P,beta-lactamase_39_109,TEM-1,beta-lactamase_39,P62593,1.01538,NO,109,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.734,-2.825,1.091,,0.787,G,A,2.34,2.21,7.243,,72.73,ABB,-1.63333,0.0495842,0.00462493,1.01538 beta-lactamase_625_E195D,beta-lactamase_625_195,TEM-1,beta-lactamase_625,P62593,1.01538,NO,195,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.186,-1.979,-0.207,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.213352,0.00496565,1.01538 PSD95pdz3_L342R,PSD95pdz3_342,PSD95pdz3,PSD95pdz3,P31016,1.01538,NO,342,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.347,-3.615,2.268,5.03015,,,,,12.0762,,,,HHH,-1.428,0.0758425,0.00081112,1.01538 beta-lactamase_156_Y95M,beta-lactamase_156_95,TEM-1,beta-lactamase_156,P62593,1.01539,NO,95,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-1.715,-4.404,2.689,,0.122,,b,0.21,-0.37,2.341,,77.62,BHP,-2.16167,0.111618,0.00479449,1.01539 beta-lactamase_39_S80G,beta-lactamase_39_80,TEM-1,beta-lactamase_39,P62593,1.01539,NO,80,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.029,-3.327,1.298,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.0495842,0.00565569,1.01539 beta-lactamase_625_L191V,beta-lactamase_625_191,TEM-1,beta-lactamase_625,P62593,1.01539,NO,191,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.087,-2.22,1.133,,,H,A,0.55,0.09,1.908,,63.29,BHH,-1.445,0.213352,0.00263549,1.01539 beta-lactamase_156_E210I,beta-lactamase_156_210,TEM-1,beta-lactamase_156,P62593,1.0154,NO,210,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.319,-2.456,0.137,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.111618,0.00663582,1.0154 PSD95pdz3_A390C,PSD95pdz3_390,PSD95pdz3,PSD95pdz3,P31016,1.01542,NO,390,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.307,-4.094,2.787,5.03823,,,,,12.46,,,,HHP,-1.54467,0.0758425,0.00104603,1.01542 beta-lactamase_625_S256F,beta-lactamase_625_256,TEM-1,beta-lactamase_625,P62593,1.01543,NO,256,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.213352,0.00710634,1.01543 beta-lactamase_156_D212M,beta-lactamase_156_212,TEM-1,beta-lactamase_156,P62593,1.01544,NO,212,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.624,-4.83,3.206,,0.037,,b,0.75,-0.58,20.222,20.222,74.48,HAB,-1.77667,0.111618,0.00644302,1.01544 beta-lactamase_2500_Q88W,beta-lactamase_2500_88,TEM-1,beta-lactamase_2500,P62593,1.01544,NO,88,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.086,-5.502,3.416,,0.807,,B,0.64,2.03,1.84,,77.62,APH,-1.53433,0.361275,0.00504167,1.01544 beta-lactamase_625_G39F,beta-lactamase_625_39,TEM-1,beta-lactamase_625,P62593,1.01545,NO,39,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.864,-4.451,2.587,,0.701,T,L,0.29,0.47,29.926,29.926,77.62,HOH,-1.53633,0.213352,0.00487611,1.01545 beta-lactamase_625_Q204I,beta-lactamase_625_204,TEM-1,beta-lactamase_625,P62593,1.01545,NO,204,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-1.382,-3.968,2.586,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.213352,0.00364106,1.01545 beta-lactamase_Q265L,beta-lactamase_265,TEM-1,beta-lactamase,P62593,1.01545,NO,265,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.58,-3.024,0.444,6.62674,1.116,,A,0.03,1.17,12.514,12.514,69.58,PPH,-1.978,0.221079,0.00811926,1.01545 beta-lactamase_156_R275D,beta-lactamase_156_275,TEM-1,beta-lactamase_156,P62593,1.01546,NO,275,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.111618,0.0141984,1.01546 beta-lactamase_625_P255C,beta-lactamase_625_255,TEM-1,beta-lactamase_625,P62593,1.01546,NO,255,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.213352,0.00499612,1.01546 beta-lactamase_156_W208F,beta-lactamase_156_208,TEM-1,beta-lactamase_156,P62593,1.01547,NO,208,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-0.818,-3.392,2.574,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.111618,0.00126609,1.01547 beta-lactamase_39_G114Y,beta-lactamase_39_114,TEM-1,beta-lactamase_39,P62593,1.01547,NO,114,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.094,-4.391,3.297,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.0495842,0.00224919,1.01547 beta-lactamase_625_T112G,beta-lactamase_625_112,TEM-1,beta-lactamase_625,P62593,1.01547,NO,112,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.186,-1.822,-0.364,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.213352,0.00531334,1.01547 beta-lactamase_0_R220F,beta-lactamase_0_220,TEM-1,beta-lactamase_0,P62593,1.01548,NO,220,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-0.942,-4.29,3.348,,0.295,I,A,1.2,-0.76,21.573,21.573,74.48,HBP,-1.33633,0.0500837,0.00232421,1.01548 beta-lactamase_625_P255F,beta-lactamase_625_255,TEM-1,beta-lactamase_625,P62593,1.01548,NO,255,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.213352,0.00499612,1.01548 gb1_I232Q,gb1_232,gb1,gb1,P06654,1.01548,NO,232,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-2.175,-4.001,1.826,,,,,,,0.766,,44.87,HHH,-2.152,0.177985,0.00580459,1.01548 gb1_I232R,gb1_232,gb1,gb1,P06654,1.01548,NO,232,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-2.175,-3.879,1.704,,,,,,,0.766,,44.87,HHH,-2.152,0.177985,0.00580459,1.01548 gb1_K276S,gb1_276,gb1,gb1,P06654,1.01548,NO,276,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.456,-3.091,1.635,,,,,,,0.236,,12.72,PBP,-1.65133,0.177985,0.00620493,1.01548 beta-lactamase_0_E210H,beta-lactamase_0_210,TEM-1,beta-lactamase_0,P62593,1.01549,NO,210,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.319,-4.778,2.459,,0.476,H,A,1.04,0.75,3.618,,77.62,HAH,-1.88567,0.0500837,0.00663582,1.01549 beta-lactamase_156_F228A,beta-lactamase_156_228,TEM-1,beta-lactamase_156,P62593,1.01549,NO,228,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-2.342,-2.562,0.22,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.111618,0.0046669,1.01549 beta-lactamase_625_G236A,beta-lactamase_625_236,TEM-1,beta-lactamase_625,P62593,1.01549,NO,236,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.784,-2.29,1.506,,0.241,,b,0.29,-0.59,3.506,,64.69,HOO,-1.025,0.213352,0.00162372,1.01549 beta-lactamase_E61M,beta-lactamase_61,TEM-1,beta-lactamase,P62593,1.0155,NO,61,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.115,-4.881,2.766,6.29701,0.775,T,a,0.52,1.29,1.975,,77.62,OAA,-1.92567,0.221079,0.00440955,1.0155 beta-lactamase_156_R162N,beta-lactamase_156_162,TEM-1,beta-lactamase_156,P62593,1.01551,NO,162,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.016,-3.588,2.572,,0.124,S,B,1.2,-0.37,7.444,,64.69,ABH,-1.25,0.111618,0.000561334,1.01551 beta-lactamase_39_R275C,beta-lactamase_39_275,TEM-1,beta-lactamase_39,P62593,1.01551,NO,275,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.0495842,0.0141984,1.01551 beta-lactamase_156_P224C,beta-lactamase_156_224,TEM-1,beta-lactamase_156,P62593,1.01552,NO,224,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.893,-5.08,4.187,,0.383,,B,0.52,-0.3,0.383,,74.48,HOH,-1.26433,0.111618,0.00189564,1.01552 beta-lactamase_V106L,beta-lactamase_106,TEM-1,beta-lactamase,P62593,1.01552,NO,106,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.218,-2.154,0.936,5.23115,0.258,T,A,0.96,0.24,1.188,,72.73,OHP,-1.04933,0.221079,0.00304168,1.01552 beta-lactamase_156_S201Q,beta-lactamase_156_201,TEM-1,beta-lactamase_156,P62593,1.01553,NO,201,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.183,-2.836,1.653,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.111618,0.00198815,1.01553 beta-lactamase_39_R91V,beta-lactamase_39_91,TEM-1,beta-lactamase_39,P62593,1.01553,NO,91,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.392,-3.661,2.269,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.0495842,0.00380226,1.01553 beta-lactamase_156_E61T,beta-lactamase_156_61,TEM-1,beta-lactamase_156,P62593,1.01555,NO,61,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.115,-3.52,1.405,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.111618,0.00440955,1.01555 beta-lactamase_39_L146N,beta-lactamase_39_146,TEM-1,beta-lactamase_39,P62593,1.01555,NO,146,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.462,-4.208,2.746,,0.007,H,A,0.55,-0.56,1.953,,64.69,AHP,-1.656,0.0495842,0.00474542,1.01555 beta-lactamase_625_S201C,beta-lactamase_625_201,TEM-1,beta-lactamase_625,P62593,1.01555,NO,201,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.183,-4.753,3.57,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.213352,0.00198815,1.01555 beta-lactamase_0_N98A,beta-lactamase_0_98,TEM-1,beta-lactamase_0,P62593,1.01556,NO,98,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-2.973,-2.132,-0.841,,0.963,G,A,0.61,1.35,14.853,14.853,77.62,PPA,-2.07867,0.0500837,0.00505389,1.01556 beta-lactamase_2500_D252N,beta-lactamase_2500_252,TEM-1,beta-lactamase_2500,P62593,1.01556,NO,252,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.94,,,,0.766,,B,1.59,1.16,,,67.83,OAO,-2.0965,0.361275,0.00575769,1.01556 beta-lactamase_156_S104V,beta-lactamase_156_104,TEM-1,beta-lactamase_156,P62593,1.01557,NO,104,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.015,-3.487,2.472,,0.04,,b,0.27,0.57,4.02,,63.29,HPO,-1.05267,0.111618,0.00218083,1.01557 beta-lactamase_39_S241T,beta-lactamase_39_241,TEM-1,beta-lactamase_39,P62593,1.01557,NO,241,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.0495842,0.00452736,1.01557 beta-lactamase_39_A200L,beta-lactamase_39_200,TEM-1,beta-lactamase_39,P62593,1.01558,NO,200,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.878,-3.527,1.649,,0.757,H,A,0.46,-0.19,1.54,,77.62,HHP,-2.001,0.0495842,0.0060056,1.01558 beta-lactamase_39_T138M,beta-lactamase_39_138,TEM-1,beta-lactamase_39,P62593,1.01558,NO,138,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.506,-4.821,2.315,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.0495842,0.00487868,1.01558 beta-lactamase_625_D36N,beta-lactamase_625_36,TEM-1,beta-lactamase_625,P62593,1.01558,NO,36,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.732,-3.002,0.27,,0.555,H,A,0.75,1.17,2.26,,77.62,AAP,-1.91167,0.213352,0.00476483,1.01558 beta-lactamase_156_A170Y,beta-lactamase_156_170,TEM-1,beta-lactamase_156,P62593,1.01559,NO,170,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.237,-4.057,2.82,,0.126,,L,0.46,-0.35,3.7,,64.69,AHH,-1.63267,0.111618,0.00431903,1.01559 beta-lactamase_39_M127Q,beta-lactamase_39_127,TEM-1,beta-lactamase_39,P62593,1.01559,NO,127,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-2.251,-2.96,0.709,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.0495842,0.00437927,1.01559 beta-lactamase_A211Q,beta-lactamase_211,TEM-1,beta-lactamase,P62593,1.01559,NO,211,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.896,-3.096,1.2,5.54662,0.369,T,A,0.52,-0.69,2.061,,77.62,AHA,-1.94633,0.221079,0.00648183,1.01559 beta-lactamase_A9Y,beta-lactamase_9,TEM-1,beta-lactamase,P62593,1.01559,NO,9,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.147,-2.967,0.82,,,,,,,5.128,,72.73,HHH,-2.04267,0.221079,0.00247263,1.01559 beta-lactamase_I171W,beta-lactamase_171,TEM-1,beta-lactamase,P62593,1.01559,NO,171,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-2.431,-5.376,2.945,5.22771,0.361,,B,1,0.53,1.66,,77.62,HHO,-1.55533,0.221079,0.00623355,1.01559 beta-lactamase_Q203M,beta-lactamase_203,TEM-1,beta-lactamase,P62593,1.01559,NO,203,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.168,-4.659,2.491,5.65296,0.47,H,A,0.12,-0.38,1.66,,65.38,BPP,-1.614,0.221079,0.00631514,1.01559 beta-lactamase_S51T,beta-lactamase_51,TEM-1,beta-lactamase,P62593,1.01559,NO,51,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.526,-1.846,0.32,5.06164,0.496,T,A,0.25,0.26,1.699,,72.73,PPO,-1.88467,0.221079,0.00504821,1.01559 beta-lactamase_625_E61Q,beta-lactamase_625_61,TEM-1,beta-lactamase_625,P62593,1.0156,NO,61,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.115,-2.702,0.587,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.213352,0.00440955,1.0156 beta-lactamase_156_F149L,beta-lactamase_156_149,TEM-1,beta-lactamase_156,P62593,1.01561,NO,149,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.299,-3.137,1.838,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.111618,0.00418462,1.01561 beta-lactamase_156_G39M,beta-lactamase_156_39,TEM-1,beta-lactamase_156,P62593,1.01561,NO,39,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.864,-4.879,3.015,,0.701,T,L,0.29,0.47,1.454,,77.62,HOH,-1.53633,0.111618,0.00487611,1.01561 beta-lactamase_39_R41S,beta-lactamase_39_41,TEM-1,beta-lactamase_39,P62593,1.01561,NO,41,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-0.942,-2.526,1.584,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.0495842,0.00123327,1.01561 beta-lactamase_625_A268C,beta-lactamase_625_268,TEM-1,beta-lactamase_625,P62593,1.01561,NO,268,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.213352,0.0102525,1.01561 kka2_1:8_C31V,kka2_1:8_31,Kka2,kka2_1:8,P00552,1.01561,NO,31,C,V,CV,Special,Hydrophobic,5.07,5.60847,0.538465,192,121,117,-4,108.5,140,31.5,-2.246,-2.747,0.501,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.100394,0.00681582,1.01561 kka2_1:8_C31V,kka2_1:8_31,Kka2,kka2_1:8,P00552,1.01561,NO,31,C,V,CV,Special,Hydrophobic,5.07,5.60847,0.538465,192,121,117,-4,108.5,140,31.5,-2.246,-2.747,0.501,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.100394,0.00681582,1.01561 beta-lactamase_625_S80E,beta-lactamase_625_80,TEM-1,beta-lactamase_625,P62593,1.01562,NO,80,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.029,-2.666,0.637,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.213352,0.00565569,1.01562 beta-lactamase_625_T138Y,beta-lactamase_625_138,TEM-1,beta-lactamase_625,P62593,1.01562,NO,138,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.506,-4.429,1.923,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.213352,0.00487868,1.01562 gb1_K236H,gb1_236,gb1,gb1,P06654,1.01563,NO,236,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-2.119,-4.16,2.041,,,,,,,1.083,,45.54,OBP,-1.758,0.177985,0.00255408,1.01563 gb1_V247C,gb1_247,gb1,gb1,P06654,1.01563,NO,247,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.711,-4.503,2.792,,,,,,,0.805,,44.87,HHA,-1.485,0.177985,0.00435373,1.01563 beta-lactamase_625_S122N,beta-lactamase_625_122,TEM-1,beta-lactamase_625,P62593,1.01565,NO,122,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.406,-3.042,0.636,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.213352,0.00497825,1.01565 beta-lactamase_625_T186M,beta-lactamase_625_186,TEM-1,beta-lactamase_625,P62593,1.01567,NO,186,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.522,-3.419,0.897,,0.396,H,A,0.22,-0.28,0.515,,77.62,HPP,-1.77633,0.213352,0.00485034,1.01567 beta-lactamase_39_L74V,beta-lactamase_39_74,TEM-1,beta-lactamase_39,P62593,1.01568,NO,74,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.296,-2.972,1.676,,,H,A,0.55,-0.91,1.581,,50,HHO,-1.34933,0.0495842,0.00493255,1.01568 PSD95pdz3_E352C,PSD95pdz3_352,PSD95pdz3,PSD95pdz3,P31016,1.01568,NO,352,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.587,-4.629,3.042,5.49659,,,,,24.2,2.525,,86.88,OAH,-1.314,0.0758425,0.000892231,1.01568 beta-lactamase_156_L284A,beta-lactamase_156_284,TEM-1,beta-lactamase_156,P62593,1.01569,NO,284,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.111618,0.0686156,1.01569 beta-lactamase_39_M270D,beta-lactamase_39_270,TEM-1,beta-lactamase_39,P62593,1.0157,NO,270,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.0495842,0.00767762,1.0157 beta-lactamase_39_T187G,beta-lactamase_39_187,TEM-1,beta-lactamase_39,P62593,1.0157,NO,187,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.401,-3.394,1.993,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.0495842,0.00491782,1.0157 beta-lactamase_625_F58I,beta-lactamase_625_58,TEM-1,beta-lactamase_625,P62593,1.01571,NO,58,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-2.914,-3.971,1.057,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.213352,0.00523369,1.01571 beta-lactamase_K252E,beta-lactamase_252,TEM-1,beta-lactamase,P62593,1.01571,NO,252,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.94,-2.765,0.825,5.56823,0.766,,B,1.82,1.16,21.796,21.796,67.83,OBO,-2.03333,0.221079,0.00575769,1.01571 beta-lactamase_2500_T139E,beta-lactamase_2500_139,TEM-1,beta-lactamase_2500,P62593,1.01572,NO,139,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.901,-2.44,0.539,,0.216,H,A,0.22,0.39,2.256,,77.62,PPH,-2.04667,0.361275,0.00441837,1.01572 beta-lactamase_625_G216M,beta-lactamase_625_216,TEM-1,beta-lactamase_625,P62593,1.01572,NO,216,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.477,-4.925,3.448,,0.437,I,A,0.29,-0.58,1.718,,74.48,HOO,-1.68067,0.213352,0.00639568,1.01572 beta-lactamase_625_S80W,beta-lactamase_625_80,TEM-1,beta-lactamase_625,P62593,1.01575,NO,80,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.029,-5.529,3.5,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.213352,0.00565569,1.01575 kka2_1:2_E235D,kka2_1:2_235,Kka2,kka2_1:2,P00552,1.01575,NO,235,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.955,-2.602,0.647,,0.631,H,A,1.04,0.12,26.048,26.048,65.53,OAH,-2.07267,0.295029,0.0102806,1.01575 beta-lactamase_39_V78A,beta-lactamase_39_78,TEM-1,beta-lactamase_39,P62593,1.01576,NO,78,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.459,-3.121,1.662,,,H,A,0.44,-0.47,1.132,,63.64,HHH,-1.17833,0.0495842,0.00492501,1.01576 beta-lactamase_625_G39Q,beta-lactamase_625_39,TEM-1,beta-lactamase_625,P62593,1.01577,NO,39,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.864,-2.885,1.021,,0.701,T,L,0.29,0.47,29.926,29.926,77.62,HOH,-1.53633,0.213352,0.00487611,1.01577 beta-lactamase_L219L,beta-lactamase_219,TEM-1,beta-lactamase,P62593,1.01577,NO,219,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.313,-1.313,,5.74153,,I,A,0.84,-0.51,2.321,,74.48,HHB,-1.21533,0.221079,0.00664345,1.01577 beta-lactamase_156_L160T,beta-lactamase_156_160,TEM-1,beta-lactamase_156,P62593,1.0158,NO,160,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.977,-3.438,2.461,,0.022,,B,0.55,-0.6,1.095,,44.41,BHA,-0.936,0.111618,0.00193775,1.0158 beta-lactamase_39_I258G,beta-lactamase_39_258,TEM-1,beta-lactamase_39,P62593,1.0158,NO,258,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.0495842,0.007931,1.0158 beta-lactamase_625_E195Y,beta-lactamase_625_195,TEM-1,beta-lactamase_625,P62593,1.0158,NO,195,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.186,-4.374,2.188,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.213352,0.00496565,1.0158 beta-lactamase_625_F58A,beta-lactamase_625_58,TEM-1,beta-lactamase_625,P62593,1.0158,NO,58,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-2.914,-3.389,0.475,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.213352,0.00523369,1.0158 PSD95pdz3_K393E,PSD95pdz3_393,PSD95pdz3,PSD95pdz3,P31016,1.0158,NO,393,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.416,-2.672,1.256,5.42682,,,,,22.0122,,,,HBO,-1.4265,0.0758425,0.000879298,1.0158 beta-lactamase_39_G234S,beta-lactamase_39_234,TEM-1,beta-lactamase_39,P62593,1.01581,NO,234,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.62,-3.161,2.541,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.0495842,0.000889577,1.01581 beta-lactamase_39_S80M,beta-lactamase_39_80,TEM-1,beta-lactamase_39,P62593,1.01582,NO,80,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.029,-4.671,2.642,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.0495842,0.00565569,1.01582 beta-lactamase_625_G226Q,beta-lactamase_625_226,TEM-1,beta-lactamase_625,P62593,1.01582,NO,226,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.461,-3.959,2.498,,0.701,T,l,0.29,-0.25,3.199,,74.48,HOH,-1.42933,0.213352,0.00665294,1.01582 beta-lactamase_39_V260N,beta-lactamase_39_260,TEM-1,beta-lactamase_39,P62593,1.01583,NO,260,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.0495842,0.00471757,1.01583 beta-lactamase_625_N152C,beta-lactamase_625_152,TEM-1,beta-lactamase_625,P62593,1.01583,NO,152,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-2.757,-5.071,2.314,,0.863,H,A,0.61,0.92,2.061,,77.62,BPH,-2.97,0.213352,0.00471429,1.01583 beta-lactamase_625_R118I,beta-lactamase_625_118,TEM-1,beta-lactamase_625,P62593,1.01583,NO,118,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.413,-3.968,1.555,,0.457,H,A,1.2,1.39,2.144,,77.62,HBA,-1.785,0.213352,0.00538794,1.01583 beta-lactamase_39_V214E,beta-lactamase_39_214,TEM-1,beta-lactamase_39,P62593,1.01584,NO,214,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.299,-3.704,2.405,,0.375,S,A,0.44,-0.44,18.838,18.838,74.48,BHH,-1.53733,0.0495842,0.00628442,1.01584 beta-lactamase_156_E145Y,beta-lactamase_156_145,TEM-1,beta-lactamase_156,P62593,1.01585,NO,145,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.357,-4.381,2.024,,0.545,H,A,1.04,0.79,3.661,,77.62,BAH,-2.069,0.111618,0.00553285,1.01585 beta-lactamase_156_D271T,beta-lactamase_156_271,TEM-1,beta-lactamase_156,P62593,1.01586,NO,271,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.111618,0.00752082,1.01586 beta-lactamase_156_V214K,beta-lactamase_156_214,TEM-1,beta-lactamase_156,P62593,1.01586,NO,214,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.299,-3.699,2.4,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.111618,0.00628442,1.01586 beta-lactamase_39_E279H,beta-lactamase_39_279,TEM-1,beta-lactamase_39,P62593,1.01586,NO,279,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.0495842,0.0192826,1.01586 PSD95pdz3_N369S,PSD95pdz3_369,PSD95pdz3,PSD95pdz3,P31016,1.01586,NO,369,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-1.572,-1.86,0.288,5.91569,,,,,24.1262,0.44,,87.71,BPH,-1.487,0.0758425,0.000608412,1.01586 beta-lactamase_625_Q88D,beta-lactamase_625_88,TEM-1,beta-lactamase_625,P62593,1.01587,NO,88,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.086,-2.035,-0.051,,0.807,,B,0.64,2.03,1.84,,77.62,APH,-1.53433,0.213352,0.00504167,1.01587 beta-lactamase_625_R91N,beta-lactamase_625_91,TEM-1,beta-lactamase_625,P62593,1.01587,NO,91,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.392,-3.596,2.204,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.213352,0.00380226,1.01587 beta-lactamase_39_R118L,beta-lactamase_39_118,TEM-1,beta-lactamase_39,P62593,1.01588,NO,118,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.413,-2.872,0.459,,0.457,H,A,1.2,1.39,3.961,,77.62,HBA,-1.785,0.0495842,0.00538794,1.01588 beta-lactamase_625_T187N,beta-lactamase_625_187,TEM-1,beta-lactamase_625,P62593,1.01591,NO,187,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.401,-2.373,0.972,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.213352,0.00491782,1.01591 beta-lactamase_156_E26K,beta-lactamase_156_26,TEM-1,beta-lactamase_156,P62593,1.01592,NO,26,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.454,-3.374,0.92,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.111618,0.00297948,1.01592 beta-lactamase_156_L223K,beta-lactamase_156_223,TEM-1,beta-lactamase_156,P62593,1.01592,NO,223,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.055,-3.742,2.687,,0.27,,B,0.55,0.09,1.511,,74.48,HHO,-1.35033,0.111618,0.00372793,1.01592 beta-lactamase_625_Q37E,beta-lactamase_625_37,TEM-1,beta-lactamase_625,P62593,1.01593,NO,37,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.134,-2.427,0.293,,0.613,H,A,0.64,1.98,1.318,,73.08,APH,-2.06967,0.213352,0.00425833,1.01593 beta-lactamase_156_R273A,beta-lactamase_156_273,TEM-1,beta-lactamase_156,P62593,1.01595,NO,273,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.314,-1.856,-0.458,,0.564,H,A,1.2,1.57,20.248,20.248,73.78,ABP,-1.841,0.111618,0.0077952,1.01595 beta-lactamase_39_D174G,beta-lactamase_39_174,TEM-1,beta-lactamase_39,P62593,1.01595,NO,174,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.738,-3.133,2.395,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.0495842,0.00125633,1.01595 beta-lactamase_39_G194I,beta-lactamase_39_194,TEM-1,beta-lactamase_39,P62593,1.01595,NO,194,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.396,-4.133,2.737,,0.276,S,b,0.29,0.36,4.852,,67.83,POA,-1.832,0.0495842,0.00392163,1.01595 beta-lactamase_39_G236N,beta-lactamase_39_236,TEM-1,beta-lactamase_39,P62593,1.01596,NO,236,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.784,-3.509,2.725,,0.241,,b,0.29,-0.59,1.883,,64.69,HOO,-1.025,0.0495842,0.00162372,1.01596 beta-lactamase_625_T138G,beta-lactamase_625_138,TEM-1,beta-lactamase_625,P62593,1.01596,NO,138,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.506,-2.767,0.261,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.213352,0.00487868,1.01596 beta-lactamase_625_T186G,beta-lactamase_625_186,TEM-1,beta-lactamase_625,P62593,1.01596,NO,186,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.522,-2.403,-0.119,,0.396,H,A,0.22,-0.28,0.515,,77.62,HPP,-1.77633,0.213352,0.00485034,1.01596 beta-lactamase_0_E102V,beta-lactamase_0_102,TEM-1,beta-lactamase_0,P62593,1.01598,NO,102,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.118,-3.638,1.52,,0.722,S,B,1.04,1.82,4.773,,73.08,HAH,-1.581,0.0500837,0.00486633,1.01598 beta-lactamase_156_R118E,beta-lactamase_156_118,TEM-1,beta-lactamase_156,P62593,1.01598,NO,118,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.413,-2.454,0.041,,0.457,H,A,1.2,1.39,2.231,,77.62,HBA,-1.785,0.111618,0.00538794,1.01598 beta-lactamase_2500_I54V,beta-lactamase_2500_54,TEM-1,beta-lactamase_2500,P62593,1.01598,NO,54,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-2.838,-2.687,-0.151,,0.669,E,B,0.48,-0.14,3.946,,73.78,BHH,-2.337,0.361275,0.00403589,1.01598 kka2_1:4_E199I,kka2_1:4_199,Kka2,kka2_1:4,P00552,1.01599,NO,199,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.234,-3.975,1.741,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.168804,0.00854122,1.01599 kka2_1:4_Q219L,kka2_1:4_219,Kka2,kka2_1:4,P00552,1.01599,NO,219,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-0.93,-3.41,2.48,,0.088,H,A,0.64,-0.85,1.537,,50,HPA,-1.05167,0.168804,0.00237913,1.01599 beta-lactamase_625_E61Y,beta-lactamase_625_61,TEM-1,beta-lactamase_625,P62593,1.016,NO,61,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.115,-4.403,2.288,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.213352,0.00440955,1.016 beta-lactamase_625_Q97R,beta-lactamase_625_97,TEM-1,beta-lactamase_625,P62593,1.01601,NO,97,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.072,-2.428,0.356,,0.823,G,A,0.64,2.42,16.954,16.954,77.62,PPP,-2.43833,0.213352,0.0045116,1.01601 beta-lactamase_39_Q267W,beta-lactamase_39_267,TEM-1,beta-lactamase_39,P62593,1.01602,NO,267,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.0495842,0.0102128,1.01602 beta-lactamase_625_E61V,beta-lactamase_625_61,TEM-1,beta-lactamase_625,P62593,1.01602,NO,61,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.115,-3.784,1.669,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.213352,0.00440955,1.01602 PSD95pdz3_N381C,PSD95pdz3_381,PSD95pdz3,PSD95pdz3,P31016,1.01602,NO,381,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-1.41,-4.769,3.359,5.66057,,,,,28.2162,,,,BPH,-1.37767,0.0758425,0.000265374,1.01602 beta-lactamase_2500_P25R,beta-lactamase_2500_25,TEM-1,beta-lactamase_2500,P62593,1.01603,NO,25,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.526,-3.8,2.274,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.361275,0.00347571,1.01603 beta-lactamase_39_L100R,beta-lactamase_39_100,TEM-1,beta-lactamase_39,P62593,1.01603,NO,100,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.218,-4.123,2.905,,0.343,,B,0.55,0.13,8.311,,63.29,AHH,-1.23467,0.0495842,0.00413885,1.01603 beta-lactamase_39_E145P,beta-lactamase_39_145,TEM-1,beta-lactamase_39,P62593,1.01604,NO,145,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.357,-3.914,1.557,,0.545,H,A,1.04,0.79,1.199,,77.62,BAH,-2.069,0.0495842,0.00553285,1.01604 beta-lactamase_39_R59K,beta-lactamase_39_59,TEM-1,beta-lactamase_39,P62593,1.01604,NO,59,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.345,-2.351,1.006,,0.329,S,L,1.2,-0.09,1.806,,73.08,HBO,-2.24267,0.0495842,0.00318082,1.01604 beta-lactamase_A84N,beta-lactamase_84,TEM-1,beta-lactamase,P62593,1.01604,NO,84,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.651,-2.768,1.117,5.28927,0.65,T,A,0.52,0.96,1.863,,68.18,AHO,-1.24267,0.221079,0.00503822,1.01604 beta-lactamase_D33V,beta-lactamase_33,TEM-1,beta-lactamase,P62593,1.01604,NO,33,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.321,-3.488,1.167,5.05203,0.366,H,A,0.23,0.33,2.032,,77.62,BAH,-2.12133,0.221079,0.00435556,1.01604 beta-lactamase_N98A,beta-lactamase_98,TEM-1,beta-lactamase,P62593,1.01604,NO,98,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-2.973,-2.132,-0.841,6.59973,0.963,G,A,1.07,1.35,1.332,,77.62,PPA,-2.07867,0.221079,0.00505389,1.01604 beta-lactamase_39_E195R,beta-lactamase_39_195,TEM-1,beta-lactamase_39,P62593,1.01605,NO,195,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.186,-3.074,0.888,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.0495842,0.00496565,1.01605 beta-lactamase_39_H151G,beta-lactamase_39_151,TEM-1,beta-lactamase_39,P62593,1.01605,NO,151,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-2.96,-2.515,-0.445,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.0495842,0.00216946,1.01605 PSD95pdz3_E331I,PSD95pdz3_331,PSD95pdz3,PSD95pdz3,P31016,1.01605,NO,331,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.404,-3.692,2.288,5.86289,,,,,51.8889,,,,OAA,-1.22533,0.0758425,0.000950134,1.01605 kka2_1:2_R18P,kka2_1:2_18,Kka2,kka2_1:2,P00552,1.01606,NO,18,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.055,-4.134,2.079,,0.474,T,A,1.2,0.54,8.405,8.405,71.59,ABH,-1.821,0.295029,0.00724065,1.01606 kka2_1:8_S104G,kka2_1:8_104,Kka2,kka2_1:8,P00552,1.01606,NO,104,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.436,-3.347,1.911,,0.536,T,A,0.27,-1.11,1.689,,63.64,HPP,-1.91433,0.100394,0.00555207,1.01606 kka2_1:8_S104G,kka2_1:8_104,Kka2,kka2_1:8,P00552,1.01606,NO,104,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.436,-3.347,1.911,,0.536,T,A,0.27,-1.11,1.689,,63.64,HPP,-1.91433,0.100394,0.00555207,1.01606 beta-lactamase_39_T112K,beta-lactamase_39_112,TEM-1,beta-lactamase_39,P62593,1.01607,NO,112,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.186,-2.704,0.518,,0.921,T,A,0.22,1.06,2.87,,73.78,HPA,-1.925,0.0495842,0.00531334,1.01607 gb1_T243F,gb1_243,gb1,gb1,P06654,1.01607,NO,243,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.415,-3.878,2.463,,,,,,,1.083,,37.28,PPP,-1.43233,0.177985,0.00308687,1.01607 beta-lactamase_156_L74M,beta-lactamase_156_74,TEM-1,beta-lactamase_156,P62593,1.01608,NO,74,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.296,-2.987,1.691,,,H,A,0.55,-0.91,0.746,,50,HHO,-1.34933,0.111618,0.00493255,1.01608 beta-lactamase_39_I280A,beta-lactamase_39_280,TEM-1,beta-lactamase_39,P62593,1.01608,NO,280,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.708,-4.017,2.309,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.0495842,0.0530888,1.01608 beta-lactamase_156_L38F,beta-lactamase_156_38,TEM-1,beta-lactamase_156,P62593,1.01609,NO,38,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.343,-3.81,2.467,,0.088,H,A,0.55,0.2,13.556,13.556,64.34,PHO,-1.78033,0.111618,0.00373244,1.01609 beta-lactamase_156_R63C,beta-lactamase_156_63,TEM-1,beta-lactamase_156,P62593,1.01609,NO,63,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-0.943,-5.05,4.107,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.111618,0.00126938,1.01609 beta-lactamase_156_A77S,beta-lactamase_156_77,TEM-1,beta-lactamase_156,P62593,1.01611,NO,77,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.234,-2.62,1.386,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.111618,0.00282362,1.01611 beta-lactamase_2500_T112Y,beta-lactamase_2500_112,TEM-1,beta-lactamase_2500,P62593,1.01611,NO,112,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.186,-4.422,2.236,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.361275,0.00531334,1.01611 beta-lactamase_2500_Y103W,beta-lactamase_2500_103,TEM-1,beta-lactamase_2500,P62593,1.01611,NO,103,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-1.33,-2.453,1.123,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.361275,0.00443048,1.01611 beta-lactamase_39_H156M,beta-lactamase_39_156,TEM-1,beta-lactamase_39,P62593,1.01612,NO,156,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-3.156,-3.543,0.387,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.0495842,0.00468596,1.01612 kka2_1:8_M1I,kka2_1:8_1,Kka2,kka2_1:8,P00552,1.01612,NO,1,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.787,-2.748,0.961,,,,,,,16.725,16.725,62.12,NAHH,-1.787,0.100394,0.00251939,1.01612 kka2_1:8_M1I,kka2_1:8_1,Kka2,kka2_1:8,P00552,1.01612,NO,1,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.787,-2.748,0.961,,,,,,,16.725,16.725,62.12,NAHH,-1.787,0.100394,0.00251939,1.01612 beta-lactamase_E61Q,beta-lactamase_61,TEM-1,beta-lactamase,P62593,1.01613,NO,61,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.115,-2.702,0.587,6.29701,0.775,T,a,0.52,1.29,1.975,,77.62,OAA,-1.92567,0.221079,0.00440955,1.01613 beta-lactamase_K144N,beta-lactamase_144,TEM-1,beta-lactamase,P62593,1.01613,NO,144,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-2.388,-3.043,0.655,6.02507,0.863,H,A,2.81,1.27,0.515,,77.62,OBA,-1.904,0.221079,0.00481141,1.01613 Ubiquitin_D21N,Ubiquitin_21,Uba1,Ubiquitin,P0CG48,1.01613,NO,21,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.193,-2.577,1.384,4.96432,0.165,,B,0.23,-0.53,1.013,,71.82,PAP,-1.35867,0.205827,0.000465257,1.01613 Ubiquitin_D39E,Ubiquitin_39,Uba1,Ubiquitin,P0CG48,1.01613,NO,39,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.792,-2.505,0.713,5.1607,0.433,G,A,,0.55,,,,OAP,-1.754,0.205827,0.00071409,1.01613 Ubiquitin_D52E,Ubiquitin_52,Uba1,Ubiquitin,P0CG48,1.01613,NO,52,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.43,-2.528,1.098,4.75143,0.421,T,A,,0.79,,,,AAO,-1.50267,0.205827,0.000806517,1.01613 Ubiquitin_D52H,Ubiquitin_52,Uba1,Ubiquitin,P0CG48,1.01613,NO,52,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.43,-4.483,3.053,4.75143,0.421,T,A,,0.79,,,,AAO,-1.50267,0.205827,0.000806517,1.01613 Ubiquitin_D52L,Ubiquitin_52,Uba1,Ubiquitin,P0CG48,1.01613,NO,52,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.43,-3.518,2.088,4.75143,0.421,T,A,,0.79,,,,AAO,-1.50267,0.205827,0.000806517,1.01613 Ubiquitin_D52P,Ubiquitin_52,Uba1,Ubiquitin,P0CG48,1.01613,NO,52,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.43,-3.879,2.449,4.75143,0.421,T,A,,0.79,,,,AAO,-1.50267,0.205827,0.000806517,1.01613 Ubiquitin_D52Q,Ubiquitin_52,Uba1,Ubiquitin,P0CG48,1.01613,NO,52,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.43,-3.836,2.406,4.75143,0.421,T,A,,0.79,,,,AAO,-1.50267,0.205827,0.000806517,1.01613 Ubiquitin_D58C,Ubiquitin_58,Uba1,Ubiquitin,P0CG48,1.01613,NO,58,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.622,-5.057,3.435,5.06391,0.457,G,A,,-0.54,,,,PAH,-1.60267,0.205827,0.000639847,1.01613 Ubiquitin_E51Q,Ubiquitin_51,Uba1,Ubiquitin,P0CG48,1.01613,NO,51,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.534,-2.812,1.278,5.36711,0.545,,B,,0.72,,,,HAA,-1.357,0.205827,0.000868134,1.01613 Ubiquitin_E64H,Ubiquitin_64,Uba1,Ubiquitin,P0CG48,1.01613,NO,64,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.763,-3.282,1.519,5.084,0.54,T,l,,0.79,,,,BAP,-1.64433,0.205827,0.000817406,1.01613 Ubiquitin_G53F,Ubiquitin_53,Uba1,Ubiquitin,P0CG48,1.01613,NO,53,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.544,-4.163,2.619,5.32628,0.805,T,A,,-0.23,,,,AOB,-1.67033,0.205827,0.000662865,1.01613 Ubiquitin_G53I,Ubiquitin_53,Uba1,Ubiquitin,P0CG48,1.01613,NO,53,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.544,-3.933,2.389,5.32628,0.805,T,A,,-0.23,,,,AOB,-1.67033,0.205827,0.000662865,1.01613 Ubiquitin_G53L,Ubiquitin_53,Uba1,Ubiquitin,P0CG48,1.01613,NO,53,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.544,-3.574,2.03,5.32628,0.805,T,A,,-0.23,,,,AOB,-1.67033,0.205827,0.000662865,1.01613 Ubiquitin_I30L,Ubiquitin_30,Uba1,Ubiquitin,P0CG48,1.01613,NO,30,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.205,-2.117,0.912,4.80264,,H,A,,-0.51,,,,BHP,-1.45133,0.205827,0.000720128,1.01613 Ubiquitin_I3V,Ubiquitin_3,Uba1,Ubiquitin,P0CG48,1.01613,NO,3,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.402,-2.045,0.643,4.80819,,E,B,,-0.78,,,,PHH,-1.54533,0.205827,0.000836911,1.01613 Ubiquitin_L50L,Ubiquitin_50,Uba1,Ubiquitin,P0CG48,1.01613,NO,50,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.107,-1.107,0,5.19399,0.029,,B,,-0.92,,,,PHA,-1.52733,0.205827,0.000734242,1.01613 Ubiquitin_L67V,Ubiquitin_67,Uba1,Ubiquitin,P0CG48,1.01613,NO,67,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.435,-2.386,0.951,4.92156,,E,B,1.19,-1.02,6.371,6.371,30.8,PHB,-1.628,0.205827,0.000482727,1.01613 Ubiquitin_P37A,Ubiquitin_37,Uba1,Ubiquitin,P0CG48,1.01613,NO,37,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.275,-2.235,0.96,5.06918,0.323,,B,,-0.09,,,,HOO,-1.49,0.205827,0.000600764,1.01613 Ubiquitin_P37Q,Ubiquitin_37,Uba1,Ubiquitin,P0CG48,1.01613,NO,37,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.275,-3.954,2.679,5.06918,0.323,,B,,-0.09,,,,HOO,-1.49,0.205827,0.000600764,1.01613 Ubiquitin_P37S,Ubiquitin_37,Uba1,Ubiquitin,P0CG48,1.01613,NO,37,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.275,-2.604,1.329,5.06918,0.323,,B,,-0.09,,,,HOO,-1.49,0.205827,0.000600764,1.01613 Ubiquitin_P38D,Ubiquitin_38,Uba1,Ubiquitin,P0CG48,1.01613,NO,38,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.718,-3.656,1.938,5.0146,0.316,G,A,,-0.52,,,,OOA,-1.595,0.205827,0.000781418,1.01613 Ubiquitin_P38I,Ubiquitin_38,Uba1,Ubiquitin,P0CG48,1.01613,NO,38,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.718,-2.745,1.027,5.0146,0.316,G,A,,-0.52,,,,OOA,-1.595,0.205827,0.000781418,1.01613 Ubiquitin_P38K,Ubiquitin_38,Uba1,Ubiquitin,P0CG48,1.01613,NO,38,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.718,-3.63,1.912,5.0146,0.316,G,A,,-0.52,,,,OOA,-1.595,0.205827,0.000781418,1.01613 Ubiquitin_P38M,Ubiquitin_38,Uba1,Ubiquitin,P0CG48,1.01613,NO,38,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.718,-4.59,2.872,5.0146,0.316,G,A,,-0.52,,,,OOA,-1.595,0.205827,0.000781418,1.01613 Ubiquitin_P38Q,Ubiquitin_38,Uba1,Ubiquitin,P0CG48,1.01613,NO,38,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.718,-3.086,1.368,5.0146,0.316,G,A,,-0.52,,,,OOA,-1.595,0.205827,0.000781418,1.01613 Ubiquitin_P38R,Ubiquitin_38,Uba1,Ubiquitin,P0CG48,1.01613,NO,38,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.718,-3.962,2.244,5.0146,0.316,G,A,,-0.52,,,,OOA,-1.595,0.205827,0.000781418,1.01613 Ubiquitin_P38S,Ubiquitin_38,Uba1,Ubiquitin,P0CG48,1.01613,NO,38,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.718,-2.816,1.098,5.0146,0.316,G,A,,-0.52,,,,OOA,-1.595,0.205827,0.000781418,1.01613 Ubiquitin_P38T,Ubiquitin_38,Uba1,Ubiquitin,P0CG48,1.01613,NO,38,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.718,-2.835,1.117,5.0146,0.316,G,A,,-0.52,,,,OOA,-1.595,0.205827,0.000781418,1.01613 Ubiquitin_P38V,Ubiquitin_38,Uba1,Ubiquitin,P0CG48,1.01613,NO,38,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.718,-3.413,1.695,5.0146,0.316,G,A,,-0.52,,,,OOA,-1.595,0.205827,0.000781418,1.01613 Ubiquitin_Q31E,Ubiquitin_31,Uba1,Ubiquitin,P0CG48,1.01613,NO,31,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-1.678,-2.36,0.682,4.5004,0.464,H,A,,0.68,,,,HPA,-1.44467,0.205827,0.000724141,1.01613 Ubiquitin_Q31H,Ubiquitin_31,Uba1,Ubiquitin,P0CG48,1.01613,NO,31,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-1.678,-3.064,1.386,4.5004,0.464,H,A,,0.68,,,,HPA,-1.44467,0.205827,0.000724141,1.01613 Ubiquitin_Q62H,Ubiquitin_62,Uba1,Ubiquitin,P0CG48,1.01613,NO,62,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-1.836,-4.573,2.737,5.33616,0.762,,B,,0.79,,,,HPB,-1.66167,0.205827,0.00068944,1.01613 Ubiquitin_Q62N,Ubiquitin_62,Uba1,Ubiquitin,P0CG48,1.01613,NO,62,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-1.836,-2.92,1.084,5.33616,0.762,,B,,0.79,,,,HPB,-1.66167,0.205827,0.00068944,1.01613 Ubiquitin_Q62T,Ubiquitin_62,Uba1,Ubiquitin,P0CG48,1.01613,NO,62,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-1.836,-2.852,1.016,5.33616,0.762,,B,,0.79,,,,HPB,-1.66167,0.205827,0.00068944,1.01613 Ubiquitin_R42R,Ubiquitin_42,Uba1,Ubiquitin,P0CG48,1.01613,NO,42,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.571,-1.571,0,5.07805,0.244,E,B,0.68,-0.54,1.976,,72.85,PBH,-1.38967,0.205827,0.000622265,1.01613 Ubiquitin_S20C,Ubiquitin_20,Uba1,Ubiquitin,P0CG48,1.01613,NO,20,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.539,-4.906,3.367,5.15339,0.672,T,A,,-0.6,,,,OPA,-1.69467,0.205827,0.000670478,1.01613 Ubiquitin_S57Q,Ubiquitin_57,Uba1,Ubiquitin,P0CG48,1.01613,NO,57,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.879,-2.805,0.926,4.65125,0.456,G,A,,-0.42,,,,HPA,-1.60833,0.205827,0.000948086,1.01613 Ubiquitin_S65A,Ubiquitin_65,Uba1,Ubiquitin,P0CG48,1.01613,NO,65,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.535,-2.324,0.789,4.99442,0.168,,b,0.25,-0.68,16.756,16.756,33.87,APP,-1.626,0.205827,0.000546776,1.01613 Ubiquitin_S65H,Ubiquitin_65,Uba1,Ubiquitin,P0CG48,1.01613,NO,65,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.535,-4.594,3.059,4.99442,0.168,,b,0.25,-0.68,16.756,16.756,33.87,APP,-1.626,0.205827,0.000546776,1.01613 Ubiquitin_T55A,Ubiquitin_55,Uba1,Ubiquitin,P0CG48,1.01613,NO,55,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.599,-2.628,1.029,4.58329,0.173,B,B,,-0.68,,,,BPH,-1.65333,0.205827,0.000525703,1.01613 Ubiquitin_T55H,Ubiquitin_55,Uba1,Ubiquitin,P0CG48,1.01613,NO,55,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.599,-4.684,3.085,4.58329,0.173,B,B,,-0.68,,,,BPH,-1.65333,0.205827,0.000525703,1.01613 Ubiquitin_T55R,Ubiquitin_55,Uba1,Ubiquitin,P0CG48,1.01613,NO,55,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.599,-3.88,2.281,4.58329,0.173,B,B,,-0.68,,,,BPH,-1.65333,0.205827,0.000525703,1.01613 Ubiquitin_T66S,Ubiquitin_66,Uba1,Ubiquitin,P0CG48,1.01613,NO,66,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.58,-2.541,0.961,5.02702,0.46,E,B,0.8,-0.81,28.36,28.36,39.71,PPH,-1.51667,0.205827,0.000598414,1.01613 PSD95pdz3_R312V,PSD95pdz3_312,PSD95pdz3,PSD95pdz3,P31016,1.01614,NO,312,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.582,-3.435,1.853,5.76826,,,,,12.2409,,,,OBB,-1.46667,0.0758425,0.00196255,1.01614 beta-lactamase_S254K,beta-lactamase_254,TEM-1,beta-lactamase,P62593,1.01615,NO,254,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.126,-3.446,1.32,5.49575,0.312,,a,0.25,-0.48,24.91,24.91,69.58,OPB,-2.215,0.221079,0.00369,1.01615 beta-lactamase_2500_E210Q,beta-lactamase_2500_210,TEM-1,beta-lactamase_2500,P62593,1.01616,NO,210,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.319,-2.627,0.308,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.361275,0.00663582,1.01616 beta-lactamase_39_T178Y,beta-lactamase_39_178,TEM-1,beta-lactamase_39,P62593,1.01616,NO,178,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-0.791,-4.162,3.371,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.0495842,0.000684366,1.01616 beta-lactamase_625_E119M,beta-lactamase_625_119,TEM-1,beta-lactamase_625,P62593,1.01616,NO,119,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.412,-4.79,3.378,,0.358,H,A,1.04,0.51,1.034,,63.99,BAH,-1.623,0.213352,0.00386966,1.01616 Pab1_V198A,Pab1_198,Pab1,Pab1,P04147,1.01616,NO,198,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.113,-2.67,1.557,,0.008,E,B,0.61,0.91,,,,HHH,-1.32933,0.175299,0.000268557,1.01616 beta-lactamase_156_F58V,beta-lactamase_156_58,TEM-1,beta-lactamase_156,P62593,1.01617,NO,58,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-2.914,-3.697,0.783,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.111618,0.00523369,1.01617 beta-lactamase_39_P25M,beta-lactamase_39_25,TEM-1,beta-lactamase_39,P62593,1.01617,NO,25,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.526,-4.708,3.182,,0.624,H,A,0.52,0.14,1.157,,73.08,BOA,-2.15367,0.0495842,0.00347571,1.01617 beta-lactamase_39_A182N,beta-lactamase_39_182,TEM-1,beta-lactamase_39,P62593,1.01618,NO,182,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.777,-3.015,1.238,,0.136,H,A,0.46,-0.66,2.598,,93.01,OHH,-1.27367,0.0495842,0.00559099,1.01618 PSD95pdz3_T385Q,PSD95pdz3_385,PSD95pdz3,PSD95pdz3,P31016,1.01618,NO,385,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.533,-3.58,2.047,5.57157,,,,,23.6871,4.527,,87.71,PPH,-1.56567,0.0758425,0.000545119,1.01618 beta-lactamase_156_A183S,beta-lactamase_156_183,TEM-1,beta-lactamase_156,P62593,1.01619,NO,183,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.231,-2.011,0.78,,0.155,H,A,0.46,-0.91,23.859,23.859,77.62,HHH,-1.53367,0.111618,0.00296631,1.01619 beta-lactamase_156_K109W,beta-lactamase_156_109,TEM-1,beta-lactamase_156,P62593,1.01619,NO,109,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.734,-5.518,3.784,,0.787,G,A,2.34,2.21,6.031,,72.73,ABB,-1.63333,0.111618,0.00462493,1.01619 beta-lactamase_2500_N152M,beta-lactamase_2500_152,TEM-1,beta-lactamase_2500,P62593,1.0162,NO,152,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-2.757,-4.737,1.98,,0.863,H,A,0.61,0.92,2.061,,77.62,BPH,-2.97,0.361275,0.00471429,1.0162 beta-lactamase_A182Y,beta-lactamase_182,TEM-1,beta-lactamase,P62593,1.01621,NO,182,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.777,-4.299,2.522,4.98609,0.136,H,A,0.52,-0.66,2.032,,93.01,OHH,-1.27367,0.221079,0.00559099,1.01621 beta-lactamase_2500_K32A,beta-lactamase_2500_32,TEM-1,beta-lactamase_2500,P62593,1.01622,NO,32,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.984,-2.363,0.379,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.361275,0.00401283,1.01622 beta-lactamase_39_L135E,beta-lactamase_39_135,TEM-1,beta-lactamase_39,P62593,1.01622,NO,135,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.002,-3.919,2.917,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.0495842,0.00244423,1.01622 beta-lactamase_39_R273P,beta-lactamase_39_273,TEM-1,beta-lactamase_39,P62593,1.01622,NO,273,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.314,-2.669,0.355,,0.564,H,A,1.2,1.57,2.163,,73.78,ABP,-1.841,0.0495842,0.0077952,1.01622 kka2_1:8_P109V,kka2_1:8_109,Kka2,kka2_1:8,P00552,1.01623,NO,109,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.412,-2.937,1.525,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.100394,0.0070929,1.01623 kka2_1:8_P109V,kka2_1:8_109,Kka2,kka2_1:8,P00552,1.01623,NO,109,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.412,-2.937,1.525,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.100394,0.0070929,1.01623 beta-lactamase_156_R242A,beta-lactamase_156_242,TEM-1,beta-lactamase_156,P62593,1.01624,NO,242,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.111618,0.00452879,1.01624 beta-lactamase_625_K190M,beta-lactamase_625_190,TEM-1,beta-lactamase_625,P62593,1.01624,NO,190,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.994,-4.714,2.72,,0.371,H,A,2.34,0.16,29.753,29.753,77.62,BBH,-1.64167,0.213352,0.00574527,1.01624 beta-lactamase_156_E108T,beta-lactamase_156_108,TEM-1,beta-lactamase_156,P62593,1.01625,NO,108,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.46,-3.526,2.066,,0.572,G,A,1.04,1.87,8.602,8.602,72.73,PAB,-1.437,0.111618,0.00413372,1.01625 beta-lactamase_2500_E108S,beta-lactamase_2500_108,TEM-1,beta-lactamase_2500,P62593,1.01625,NO,108,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.46,-2.354,0.894,,0.572,G,A,1.04,1.87,1.147,,72.73,PAB,-1.437,0.361275,0.00413372,1.01625 beta-lactamase_M184I,beta-lactamase_184,TEM-1,beta-lactamase,P62593,1.01625,NO,184,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.593,-2.332,0.739,5.39575,,H,A,1.3,-0.87,2.893,,62.94,HHH,-1.41,0.221079,0.00356019,1.01625 beta-lactamase_156_I93C,beta-lactamase_156_93,TEM-1,beta-lactamase_156,P62593,1.01626,NO,93,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.401,-4.797,3.396,,0.128,E,B,0.48,0.44,1.524,,67.83,BHB,-1.873,0.111618,0.00527066,1.01626 beta-lactamase_156_E195K,beta-lactamase_156_195,TEM-1,beta-lactamase_156,P62593,1.01627,NO,195,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.186,-2.529,0.343,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.111618,0.00496565,1.01627 beta-lactamase_156_I93Y,beta-lactamase_156_93,TEM-1,beta-lactamase_156,P62593,1.01627,NO,93,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.401,-4.112,2.711,,0.128,E,B,0.48,0.44,1.524,,67.83,BHB,-1.873,0.111618,0.00527066,1.01627 beta-lactamase_156_I285T,beta-lactamase_156_285,TEM-1,beta-lactamase_156,P62593,1.01628,NO,285,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.111618,0.101555,1.01628 beta-lactamase_M66V,beta-lactamase_66,TEM-1,beta-lactamase,P62593,1.01628,NO,66,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.362,-2.395,1.033,5.29561,0.013,,A,1.3,-0.7,1.319,,73.08,OHH,-1.49567,0.221079,0.00412876,1.01628 beta-lactamase_V8N,beta-lactamase_8,TEM-1,beta-lactamase,P62593,1.01628,NO,8,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-2.358,-3.835,1.477,,,,,,,0.575,,77.62,BHH,-2.06267,0.221079,0.00226401,1.01628 kka2_1:8_A255E,kka2_1:8_255,Kka2,kka2_1:8,P00552,1.01628,NO,255,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.715,-2.621,0.906,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.100394,0.0126809,1.01628 kka2_1:8_A255E,kka2_1:8_255,Kka2,kka2_1:8,P00552,1.01628,NO,255,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.715,-2.621,0.906,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.100394,0.0126809,1.01628 beta-lactamase_156_I261V,beta-lactamase_156_261,TEM-1,beta-lactamase_156,P62593,1.0163,NO,261,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.111618,0.0123091,1.0163 beta-lactamase_156_V259F,beta-lactamase_156_259,TEM-1,beta-lactamase_156,P62593,1.0163,NO,259,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.111618,0.0070773,1.0163 beta-lactamase_39_L192T,beta-lactamase_39_192,TEM-1,beta-lactamase_39,P62593,1.0163,NO,192,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.254,-3.48,2.226,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.0495842,0.00558728,1.0163 beta-lactamase_39_R63F,beta-lactamase_39_63,TEM-1,beta-lactamase_39,P62593,1.0163,NO,63,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-0.943,-4.214,3.271,,0.218,,B,1.2,-0.31,0.326,,44.06,ABH,-0.992333,0.0495842,0.00126938,1.0163 beta-lactamase_2500_E108A,beta-lactamase_2500_108,TEM-1,beta-lactamase_2500,P62593,1.01631,NO,108,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.46,-2.613,1.153,,0.572,G,A,1.04,1.87,1.147,,72.73,PAB,-1.437,0.361275,0.00413372,1.01631 beta-lactamase_39_R220H,beta-lactamase_39_220,TEM-1,beta-lactamase_39,P62593,1.01631,NO,220,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-0.942,-4.298,3.356,,0.295,I,A,1.2,-0.76,1.596,,74.48,HBP,-1.33633,0.0495842,0.00232421,1.01631 beta-lactamase_156_P60I,beta-lactamase_156_60,TEM-1,beta-lactamase_156,P62593,1.01632,NO,60,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-2.469,-3.895,1.426,,0.256,T,A,0.52,-0.56,2.947,,77.62,BOA,-1.97633,0.111618,0.00521318,1.01632 beta-lactamase_39_M127A,beta-lactamase_39_127,TEM-1,beta-lactamase_39,P62593,1.01632,NO,127,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-2.251,-3.303,1.052,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.0495842,0.00437927,1.01632 beta-lactamase_625_L136I,beta-lactamase_625_136,TEM-1,beta-lactamase_625,P62593,1.01632,NO,136,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.232,-1.874,0.642,,,H,A,0.55,-0.34,0.336,,48.95,HHH,-1.088,0.213352,0.00442304,1.01632 beta-lactamase_A148E,beta-lactamase_148,TEM-1,beta-lactamase,P62593,1.01632,NO,148,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.757,-2.317,0.56,5.28111,0.379,H,A,0.52,-0.55,2.117,,72.73,PHH,-1.40167,0.221079,0.00547053,1.01632 beta-lactamase_39_P217Y,beta-lactamase_39_217,TEM-1,beta-lactamase_39,P62593,1.01634,NO,217,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-2.062,-4.376,2.314,,0.496,I,A,0.52,-0.33,21.172,21.172,74.48,OOH,-1.64333,0.0495842,0.00463211,1.01634 beta-lactamase_39_E87I,beta-lactamase_39_87,TEM-1,beta-lactamase_39,P62593,1.01635,NO,87,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.421,-3.687,2.266,,0.048,,B,1.04,0.92,15.231,15.231,64.69,PAP,-1.969,0.0495842,0.00337888,1.01635 beta-lactamase_E237N,beta-lactamase_237,TEM-1,beta-lactamase,P62593,1.01635,NO,237,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.058,-2.569,0.511,5.42877,0.583,S,B,1.62,1.2,2.144,,77.62,OAB,-1.61467,0.221079,0.0048626,1.01635 gb1_K236V,gb1_236,gb1,gb1,P06654,1.01636,NO,236,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-2.119,-3.36,1.241,,,,,,,1.083,,45.54,OBP,-1.758,0.177985,0.00255408,1.01636 kka2_1:8_A137T,kka2_1:8_137,Kka2,kka2_1:8,P00552,1.01636,NO,137,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.156,-3.52,1.364,,0.029,H,A,1.04,0.34,2.886,,63.26,PHB,-2.559,0.100394,0.00515054,1.01636 kka2_1:8_A137T,kka2_1:8_137,Kka2,kka2_1:8,P00552,1.01636,NO,137,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.156,-3.52,1.364,,0.029,H,A,1.04,0.34,2.886,,63.26,PHB,-2.559,0.100394,0.00515054,1.01636 beta-lactamase_G194S,beta-lactamase_194,TEM-1,beta-lactamase,P62593,1.01637,NO,194,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.396,-2.171,0.775,5.46622,0.276,S,b,0.77,0.36,3.593,,67.83,POA,-1.832,0.221079,0.00392163,1.01637 beta-lactamase_39_A148E,beta-lactamase_39_148,TEM-1,beta-lactamase_39,P62593,1.01638,NO,148,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.757,-2.317,0.56,,0.379,H,A,0.46,-0.55,3.551,,72.73,PHH,-1.40167,0.0495842,0.00547053,1.01638 beta-lactamase_39_A235H,beta-lactamase_39_235,TEM-1,beta-lactamase_39,P62593,1.01638,NO,235,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.266,-4.769,3.503,,0.32,E,B,0.46,-0.86,1.344,,50,OHO,-0.89,0.0495842,0.00493474,1.01638 beta-lactamase_625_L137I,beta-lactamase_625_137,TEM-1,beta-lactamase_625,P62593,1.01638,NO,137,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.03,-2.064,1.034,,,H,A,0.55,-0.38,1.5,,42.31,HHP,-1.58933,0.213352,0.00278599,1.01638 beta-lactamase_625_Q97V,beta-lactamase_625_97,TEM-1,beta-lactamase_625,P62593,1.01638,NO,97,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.072,-3.633,1.561,,0.823,G,A,0.64,2.42,16.954,16.954,77.62,PPP,-2.43833,0.213352,0.0045116,1.01638 beta-lactamase_156_H94M,beta-lactamase_156_94,TEM-1,beta-lactamase_156,P62593,1.01639,NO,94,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-2.5,-3.474,0.974,,0.776,,B,0.17,1.24,11.583,11.583,77.62,HBH,-1.872,0.111618,0.00389226,1.01639 beta-lactamase_625_R273M,beta-lactamase_625_273,TEM-1,beta-lactamase_625,P62593,1.01639,NO,273,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.314,-4.698,2.384,,0.564,H,A,1.2,1.57,1.455,,73.78,ABP,-1.841,0.213352,0.0077952,1.01639 beta-lactamase_156_E166H,beta-lactamase_156_166,TEM-1,beta-lactamase_156,P62593,1.0164,NO,166,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.756,-4.668,2.912,,0.508,G,A,1.04,1.05,2.393,,73.08,OAH,-1.42233,0.111618,0.00512989,1.0164 beta-lactamase_156_M270Q,beta-lactamase_156_270,TEM-1,beta-lactamase_156,P62593,1.0164,NO,270,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.111618,0.00767762,1.0164 beta-lactamase_625_E238P,beta-lactamase_625_238,TEM-1,beta-lactamase_625,P62593,1.0164,NO,238,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.213352,0.00743256,1.0164 beta-lactamase_625_F70C,beta-lactamase_625_70,TEM-1,beta-lactamase_625,P62593,1.0164,NO,70,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.169,-4.871,3.702,,,H,A,0.58,-1.34,1.14,,63.99,PHB,-0.980667,0.213352,0.00193499,1.0164 beta-lactamase_156_S283D,beta-lactamase_156_283,TEM-1,beta-lactamase_156,P62593,1.01641,NO,283,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.111618,0.0429138,1.01641 beta-lactamase_39_Y262M,beta-lactamase_39_262,TEM-1,beta-lactamase_39,P62593,1.01641,NO,262,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-1.332,,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.0495842,0.00853516,1.01641 PSD95pdz3_G319Y,PSD95pdz3_319,PSD95pdz3,PSD95pdz3,P31016,1.01641,NO,319,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.008,-4.069,3.061,4.95387,,,,,18.8725,,,,BOP,-1.36967,0.0758425,0.00109317,1.01641 beta-lactamase_39_Q88E,beta-lactamase_39_88,TEM-1,beta-lactamase_39,P62593,1.01642,NO,88,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.086,-2.76,0.674,,0.807,,B,0.64,2.03,11.108,11.108,77.62,APH,-1.53433,0.0495842,0.00504167,1.01642 beta-lactamase_39_R118H,beta-lactamase_39_118,TEM-1,beta-lactamase_39,P62593,1.01642,NO,118,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.413,-4.71,2.297,,0.457,H,A,1.2,1.39,3.961,,77.62,HBA,-1.785,0.0495842,0.00538794,1.01642 beta-lactamase_625_M180N,beta-lactamase_625_180,TEM-1,beta-lactamase_625,P62593,1.01642,NO,180,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-2.795,-3.603,0.808,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.213352,0.00552048,1.01642 beta-lactamase_Q265A,beta-lactamase_265,TEM-1,beta-lactamase,P62593,1.01642,NO,265,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.58,-2.619,0.039,6.62674,1.116,,A,0.03,1.17,12.514,12.514,69.58,PPH,-1.978,0.221079,0.00811926,1.01642 beta-lactamase_39_N173H,beta-lactamase_39_173,TEM-1,beta-lactamase_39,P62593,1.01645,NO,173,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-2.663,-4.635,1.972,,1.044,T,l,0.61,1.25,1.426,,77.62,OPA,-1.46633,0.0495842,0.0033769,1.01645 beta-lactamase_625_W208Y,beta-lactamase_625_208,TEM-1,beta-lactamase_625,P62593,1.01645,NO,208,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-0.818,-3.262,2.444,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.213352,0.00126609,1.01645 beta-lactamase_156_G39Q,beta-lactamase_156_39,TEM-1,beta-lactamase_156,P62593,1.01646,NO,39,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.864,-2.885,1.021,,0.701,T,L,0.29,0.47,1.454,,77.62,HOH,-1.53633,0.111618,0.00487611,1.01646 beta-lactamase_156_R63N,beta-lactamase_156_63,TEM-1,beta-lactamase_156,P62593,1.01646,NO,63,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-0.943,-3.531,2.588,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.111618,0.00126938,1.01646 beta-lactamase_39_T138E,beta-lactamase_39_138,TEM-1,beta-lactamase_39,P62593,1.01646,NO,138,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.506,-2.168,-0.338,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.0495842,0.00487868,1.01646 beta-lactamase_2500_T186V,beta-lactamase_2500_186,TEM-1,beta-lactamase_2500,P62593,1.01647,NO,186,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.522,-3.557,1.035,,0.396,H,A,0.22,-0.28,2.144,,77.62,HPP,-1.77633,0.361275,0.00485034,1.01647 beta-lactamase_625_L160Q,beta-lactamase_625_160,TEM-1,beta-lactamase_625,P62593,1.01647,NO,160,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.977,-4.199,3.222,,0.022,,B,0.55,-0.6,0.237,,44.41,BHA,-0.936,0.213352,0.00193775,1.01647 beta-lactamase_G85G,beta-lactamase_85,TEM-1,beta-lactamase,P62593,1.01648,NO,85,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.011,-1.011,,5.58951,0.805,T,l,0.23,1.7,1.468,,63.64,HOP,-1.68733,0.221079,0.00252173,1.01648 gb1_K236W,gb1_236,gb1,gb1,P06654,1.0165,NO,236,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-2.119,-5.222,3.103,,,,,,,1.083,,45.54,OBP,-1.758,0.177985,0.00255408,1.0165 gb1_T244A,gb1_244,gb1,gb1,P06654,1.0165,NO,244,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.637,-2.664,1.027,,,,,,,0.202,,11.83,PPA,-1.92567,0.177985,0.00222755,1.0165 kka2_1:4_G21F,kka2_1:4_21,Kka2,kka2_1:4,P00552,1.0165,NO,21,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.368,-4.373,3.005,,0.586,T,l,0.75,-0.75,3.075,,71.59,HOH,-2.10167,0.168804,0.00709648,1.0165 kka2_1:8_L170M,kka2_1:8_170,Kka2,kka2_1:8,P00552,1.0165,NO,170,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.28,-3.089,1.809,,0.029,H,A,1.59,0.11,1.453,,62.5,AHH,-1.534,0.100394,0.00730791,1.0165 kka2_1:8_L170M,kka2_1:8_170,Kka2,kka2_1:8,P00552,1.0165,NO,170,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.28,-3.089,1.809,,0.029,H,A,1.59,0.11,1.453,,62.5,AHH,-1.534,0.100394,0.00730791,1.0165 beta-lactamase_156_V29T,beta-lactamase_156_29,TEM-1,beta-lactamase_156,P62593,1.01651,NO,29,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-2.856,-2.552,-0.304,,0.733,H,A,0.44,-0.78,3.685,,93.01,HHB,-2.24733,0.111618,0.00318969,1.01651 beta-lactamase_39_Q276A,beta-lactamase_39_276,TEM-1,beta-lactamase_39,P62593,1.01651,NO,276,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-1.144,-3.872,2.728,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.0495842,0.0191712,1.01651 beta-lactamase_39_R91C,beta-lactamase_39_91,TEM-1,beta-lactamase_39,P62593,1.01651,NO,91,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.392,-5.127,3.735,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.0495842,0.00380226,1.01651 beta-lactamase_156_M67N,beta-lactamase_156_67,TEM-1,beta-lactamase_156,P62593,1.01652,NO,67,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-2.231,-2.235,0.004,,0.006,G,P,0.55,-0.81,1.463,,65.03,HHP,-1.502,0.111618,0.00409753,1.01652 beta-lactamase_A182R,beta-lactamase_182,TEM-1,beta-lactamase,P62593,1.01652,NO,182,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.777,-2.31,0.533,4.98609,0.136,H,A,0.52,-0.66,2.032,,93.01,OHH,-1.27367,0.221079,0.00559099,1.01652 beta-lactamase_39_R239E,beta-lactamase_39_239,TEM-1,beta-lactamase_39,P62593,1.01653,NO,239,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.0495842,0.00213852,1.01653 beta-lactamase_625_L28Q,beta-lactamase_625_28,TEM-1,beta-lactamase_625,P62593,1.01653,NO,28,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.579,-2.97,1.391,,0.277,H,A,0.55,-0.16,2.716,,93.01,PHH,-2.11333,0.213352,0.00359321,1.01653 beta-lactamase_625_N152L,beta-lactamase_625_152,TEM-1,beta-lactamase_625,P62593,1.01653,NO,152,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-2.757,-3.55,0.793,,0.863,H,A,0.61,0.92,2.061,,77.62,BPH,-2.97,0.213352,0.00471429,1.01653 kka2_1:8_D180W,kka2_1:8_180,Kka2,kka2_1:8,P00552,1.01653,NO,180,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.416,-5.59,3.174,,1.03,S,a,0.75,1.5,14.668,14.668,71.59,OAO,-2.02933,0.100394,0.00756412,1.01653 kka2_1:8_D180W,kka2_1:8_180,Kka2,kka2_1:8,P00552,1.01653,NO,180,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.416,-5.59,3.174,,1.03,S,a,0.75,1.5,14.668,14.668,71.59,OAO,-2.02933,0.100394,0.00756412,1.01653 beta-lactamase_156_L284V,beta-lactamase_156_284,TEM-1,beta-lactamase_156,P62593,1.01654,NO,284,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.111618,0.0686156,1.01654 beta-lactamase_39_G154D,beta-lactamase_39_154,TEM-1,beta-lactamase_39,P62593,1.01655,NO,154,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.823,-2.317,1.494,,0.54,T,l,0.29,-0.56,1.151,,64.69,HOA,-1.635,0.0495842,0.00180205,1.01655 kka2_1:8_R147K,kka2_1:8_147,Kka2,kka2_1:8,P00552,1.01656,NO,147,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.123,-3.064,1.941,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.100394,0.00549168,1.01656 kka2_1:8_R147K,kka2_1:8_147,Kka2,kka2_1:8,P00552,1.01656,NO,147,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.123,-3.064,1.941,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.100394,0.00549168,1.01656 beta-lactamase_156_L191M,beta-lactamase_156_191,TEM-1,beta-lactamase_156,P62593,1.01659,NO,191,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.087,-4.016,2.929,,,H,A,0.55,0.09,1.372,,63.29,BHH,-1.445,0.111618,0.00263549,1.01659 beta-lactamase_S281E,beta-lactamase_281,TEM-1,beta-lactamase,P62593,1.01659,NO,281,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.247,-3.626,1.379,4.73591,0.128,H,A,0.25,-0.26,2.144,,77.62,HPH,-1.847,0.221079,0.0406482,1.01659 beta-lactamase_156_L135I,beta-lactamase_156_135,TEM-1,beta-lactamase_156,P62593,1.0166,NO,135,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.002,-2.037,1.035,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.111618,0.00244423,1.0166 beta-lactamase_0_L219G,beta-lactamase_0_219,TEM-1,beta-lactamase_0,P62593,1.01661,NO,219,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.313,-3.865,2.552,,,I,A,0.55,-0.51,6.513,6.513,74.48,HHB,-1.21533,0.0500837,0.00664345,1.01661 beta-lactamase_39_Q204C,beta-lactamase_39_204,TEM-1,beta-lactamase_39,P62593,1.01661,NO,204,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-1.382,-5.114,3.732,,0.204,H,A,0.64,0.09,0.489,,66.08,PPH,-1.49067,0.0495842,0.00364106,1.01661 beta-lactamase_39_S201D,beta-lactamase_39_201,TEM-1,beta-lactamase_39,P62593,1.01661,NO,201,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.183,-3.453,2.27,,0.064,H,A,0.27,-0.07,3.54,,64.69,HPB,-1.451,0.0495842,0.00198815,1.01661 beta-lactamase_0_G249D,beta-lactamase_0_249,TEM-1,beta-lactamase_0,P62593,1.01662,NO,249,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.0500837,0.00220169,1.01662 beta-lactamase_156_A200N,beta-lactamase_156_200,TEM-1,beta-lactamase_156,P62593,1.01662,NO,200,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.878,-3.758,1.88,,0.757,H,A,0.46,-0.19,16.368,16.368,77.62,HHP,-2.001,0.111618,0.0060056,1.01662 beta-lactamase_39_A148L,beta-lactamase_39_148,TEM-1,beta-lactamase_39,P62593,1.01662,NO,148,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.757,-3.596,1.839,,0.379,H,A,0.46,-0.55,3.551,,72.73,PHH,-1.40167,0.0495842,0.00547053,1.01662 beta-lactamase_625_H110Y,beta-lactamase_625_110,TEM-1,beta-lactamase_625,P62593,1.01663,NO,110,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-1.706,-2.513,0.807,,0.341,G,a,0.17,1.08,31.31,31.31,64.69,BBH,-1.73333,0.213352,0.00441499,1.01663 beta-lactamase_0_I245M,beta-lactamase_0_245,TEM-1,beta-lactamase_0,P62593,1.01664,NO,245,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.0500837,0.00391032,1.01664 beta-lactamase_156_I171R,beta-lactamase_156_171,TEM-1,beta-lactamase_156,P62593,1.01664,NO,171,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-2.431,-2.473,0.042,,0.361,,B,0.48,0.53,3.869,,77.62,HHO,-1.55533,0.111618,0.00623355,1.01664 beta-lactamase_156_M270R,beta-lactamase_156_270,TEM-1,beta-lactamase_156,P62593,1.01664,NO,270,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.111618,0.00767762,1.01664 beta-lactamase_39_P65C,beta-lactamase_39_65,TEM-1,beta-lactamase_39,P62593,1.01665,NO,65,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.894,-5.01,4.116,,0.098,E,B,0.52,-0.62,0.623,,40.56,HOH,-1.03233,0.0495842,0.00152776,1.01665 gb1_D262H,gb1_262,gb1,gb1,P06654,1.01665,NO,262,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-3.132,-4.349,1.217,,,,,,,1.304,,45.54,PAP,-2.05233,0.177985,0.00413102,1.01665 PSD95pdz3_Q358M,PSD95pdz3_358,PSD95pdz3,PSD95pdz3,P31016,1.01665,NO,358,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-1.699,-3.937,2.238,5.21282,,,,,14.8844,,,,APH,-1.531,0.0758425,0.000594893,1.01665 beta-lactamase_156_T112N,beta-lactamase_156_112,TEM-1,beta-lactamase_156,P62593,1.01666,NO,112,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.186,-2.739,0.553,,0.921,T,A,0.22,1.06,2.87,,73.78,HPA,-1.925,0.111618,0.00531334,1.01666 beta-lactamase_39_T186M,beta-lactamase_39_186,TEM-1,beta-lactamase_39,P62593,1.01666,NO,186,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.522,-3.419,0.897,,0.396,H,A,0.22,-0.28,0.515,,77.62,HPP,-1.77633,0.0495842,0.00485034,1.01666 beta-lactamase_39_A132C,beta-lactamase_39_132,TEM-1,beta-lactamase_39,P62593,1.01668,NO,132,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.9,-4.503,3.603,,,H,A,0.46,-0.93,8.408,,64.69,PHH,-1.138,0.0495842,0.000962524,1.01668 beta-lactamase_625_I54K,beta-lactamase_625_54,TEM-1,beta-lactamase_625,P62593,1.01668,NO,54,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-2.838,-2.926,0.088,,0.669,E,B,0.48,-0.14,3.946,,73.78,BHH,-2.337,0.213352,0.00403589,1.01668 beta-lactamase_39_A183H,beta-lactamase_39_183,TEM-1,beta-lactamase_39,P62593,1.01669,NO,183,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.231,-4.624,3.393,,0.155,H,A,0.46,-0.91,1.237,,77.62,HHH,-1.53367,0.0495842,0.00296631,1.01669 beta-lactamase_39_L74A,beta-lactamase_39_74,TEM-1,beta-lactamase_39,P62593,1.01669,NO,74,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.296,-1.569,0.273,,,H,A,0.55,-0.91,1.581,,50,HHO,-1.34933,0.0495842,0.00493255,1.01669 beta-lactamase_625_E195T,beta-lactamase_625_195,TEM-1,beta-lactamase_625,P62593,1.01669,NO,195,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.186,-2.956,0.77,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.213352,0.00496565,1.01669 kka2_1:2_Q155N,kka2_1:2_155,Kka2,kka2_1:2,P00552,1.01669,NO,155,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.606,-3.65,1.044,,0.525,T,A,0.64,1.49,1.592,,63.64,APA,-1.726,0.295029,0.00641853,1.01669 beta-lactamase_2500_V29W,beta-lactamase_2500_29,TEM-1,beta-lactamase_2500,P62593,1.0167,NO,29,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-2.856,-5.465,2.609,,0.733,H,A,0.44,-0.78,1.931,,93.01,HHB,-2.24733,0.361275,0.00318969,1.0167 beta-lactamase_39_N50K,beta-lactamase_39_50,TEM-1,beta-lactamase_39,P62593,1.0167,NO,50,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-2.979,-3.578,0.599,,0.912,T,A,0.61,1.24,10.736,,77.62,HPP,-2.134,0.0495842,0.0047211,1.0167 beta-lactamase_39_V157N,beta-lactamase_39_157,TEM-1,beta-lactamase_39,P62593,1.01671,NO,157,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.751,-3.925,2.174,,0.308,S,a,0.44,-0.75,10.364,10.364,69.58,BHP,-2.00767,0.0495842,0.00506849,1.01671 beta-lactamase_625_R273N,beta-lactamase_625_273,TEM-1,beta-lactamase_625,P62593,1.01671,NO,273,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.314,-3.744,1.43,,0.564,H,A,1.2,1.57,1.455,,73.78,ABP,-1.841,0.213352,0.0077952,1.01671 PSD95pdz3_A343C,PSD95pdz3_343,PSD95pdz3,PSD95pdz3,P31016,1.01671,NO,343,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.307,-4.094,2.787,5.585,,,,,14.728,,,,HHO,-1.22067,0.0758425,0.000798084,1.01671 beta-lactamase_0_A247N,beta-lactamase_0_247,TEM-1,beta-lactamase_0,P62593,1.01672,NO,247,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.0500837,0.00611275,1.01672 beta-lactamase_156_A222L,beta-lactamase_156_222,TEM-1,beta-lactamase_156,P62593,1.01672,NO,222,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.103,-3.403,1.3,,0.233,H,A,0.46,-0.25,2.461,,77.62,PHH,-1.63733,0.111618,0.00466094,1.01672 beta-lactamase_156_S201V,beta-lactamase_156_201,TEM-1,beta-lactamase_156,P62593,1.01672,NO,201,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.183,-3.482,2.299,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.111618,0.00198815,1.01672 beta-lactamase_39_L199M,beta-lactamase_39_199,TEM-1,beta-lactamase_39,P62593,1.01672,NO,199,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-2.942,-4.728,1.786,,0.832,H,A,0.55,0.42,15.504,15.504,77.62,PHH,-2.32933,0.0495842,0.0048649,1.01672 beta-lactamase_39_Y95M,beta-lactamase_39_95,TEM-1,beta-lactamase_39,P62593,1.01672,NO,95,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-1.715,-4.404,2.689,,0.122,,b,0.21,-0.37,2.341,,77.62,BHP,-2.16167,0.0495842,0.00479449,1.01672 beta-lactamase_625_I261M,beta-lactamase_625_261,TEM-1,beta-lactamase_625,P62593,1.01672,NO,261,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.213352,0.0123091,1.01672 PSD95pdz3_F340W,PSD95pdz3_340,PSD95pdz3,PSD95pdz3,P31016,1.01672,NO,340,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.524,-4.104,2.58,5.79283,,,,,11.8045,,,,PHH,-1.55767,0.0758425,0.000836987,1.01672 beta-lactamase_A148D,beta-lactamase_148,TEM-1,beta-lactamase,P62593,1.01673,NO,148,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.757,-2.341,0.584,5.28111,0.379,H,A,0.52,-0.55,2.117,,72.73,PHH,-1.40167,0.221079,0.00547053,1.01673 beta-lactamase_A23G,beta-lactamase_23,TEM-1,beta-lactamase,P62593,1.01673,NO,23,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.548,-2.159,0.611,,,,,,,0.801,,93.01,HHB,-2.235,0.221079,0.00245563,1.01673 kka2_1:8_E169K,kka2_1:8_169,Kka2,kka2_1:8,P00552,1.01674,NO,169,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.996,-2.672,0.676,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.100394,0.00730086,1.01674 kka2_1:8_E169K,kka2_1:8_169,Kka2,kka2_1:8,P00552,1.01674,NO,169,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.996,-2.672,0.676,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.100394,0.00730086,1.01674 beta-lactamase_156_R118P,beta-lactamase_156_118,TEM-1,beta-lactamase_156,P62593,1.01675,NO,118,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.413,-3.946,1.533,,0.457,H,A,1.2,1.39,2.231,,77.62,HBA,-1.785,0.111618,0.00538794,1.01675 beta-lactamase_625_R202T,beta-lactamase_625_202,TEM-1,beta-lactamase_625,P62593,1.01675,NO,202,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.292,-3.438,2.146,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.213352,0.00321899,1.01675 beta-lactamase_156_D212Q,beta-lactamase_156_212,TEM-1,beta-lactamase_156,P62593,1.01676,NO,212,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.624,-3.949,2.325,,0.037,,b,0.75,-0.58,20.222,20.222,74.48,HAB,-1.77667,0.111618,0.00644302,1.01676 beta-lactamase_39_V259F,beta-lactamase_39_259,TEM-1,beta-lactamase_39,P62593,1.01677,NO,259,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.0495842,0.0070773,1.01677 beta-lactamase_S2N,beta-lactamase_2,TEM-1,beta-lactamase,P62593,1.01677,NO,2,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.942,-3.578,1.636,,,,,,,2.36,,65.38,HPH,-2.02767,0.221079,0.00227352,1.01677 beta-lactamase_156_A268M,beta-lactamase_156_268,TEM-1,beta-lactamase_156,P62593,1.01678,NO,268,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.023,-2.456,0.433,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.111618,0.0102525,1.01678 beta-lactamase_39_K32V,beta-lactamase_39_32,TEM-1,beta-lactamase_39,P62593,1.01678,NO,32,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.984,-3.477,1.493,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.0495842,0.00401283,1.01678 beta-lactamase_625_I54A,beta-lactamase_625_54,TEM-1,beta-lactamase_625,P62593,1.01678,NO,54,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-2.838,-2.597,-0.241,,0.669,E,B,0.48,-0.14,3.946,,73.78,BHH,-2.337,0.213352,0.00403589,1.01678 Pab1_D136H,Pab1_136,Pab1,Pab1,P04147,1.01678,NO,136,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.602,-4.556,2.954,,,,,,,,,,OAH,-1.42367,0.175299,0.00227029,1.01678 beta-lactamase_39_E279L,beta-lactamase_39_279,TEM-1,beta-lactamase_39,P62593,1.01679,NO,279,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.0495842,0.0192826,1.01679 gb1_N234C,gb1_234,gb1,gb1,P06654,1.01679,NO,234,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-2.055,-4.927,2.872,,,,,,,1.235,,45.54,HPO,-2.05067,0.177985,0.00242189,1.01679 gb1_V247N,gb1_247,gb1,gb1,P06654,1.01679,NO,247,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.711,-3.68,1.969,,,,,,,0.805,,44.87,HHA,-1.485,0.177985,0.00435373,1.01679 kka2_1:1_E199H,kka2_1:1_199,Kka2,kka2_1:1,P00552,1.01679,NO,199,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.234,-3.025,0.791,,0.508,E,B,1.04,-0.43,3.012,,65.53,HAP,-2.133,0.520039,0.00854122,1.01679 PSD95pdz3_Q384K,PSD95pdz3_384,PSD95pdz3,PSD95pdz3,P31016,1.01679,NO,384,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-1.699,-2.689,0.99,5.49339,,,,,23.54,,,,OPP,-1.41333,0.0758425,0.000216736,1.01679 beta-lactamase_625_T131L,beta-lactamase_625_131,TEM-1,beta-lactamase_625,P62593,1.0168,NO,131,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.328,-3.319,1.991,,,H,A,0.22,-0.69,2.031,,67.48,PPH,-1.00867,0.213352,0.00345886,1.0168 E1_Ubiquitin_G47T,E1_Ubiquitin_47,Uba1,E1_Ubiquitin,P0CG63,1.0168,NO,47,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.999,-3.457,2.458,,0.057,T,l,,-1.21,,,,HOB,-1.195,0.18783,0.00142261,1.0168 E1_Ubiquitin_G75G,E1_Ubiquitin_75,Uba1,E1_Ubiquitin,P0CG63,1.0168,NO,75,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.999,-0.999,,,0.552,T,A,0.75,0.9,4.369,,83.73,BOO,-1.1,0.18783,0.00153276,1.0168 E1_Ubiquitin_Q40D,E1_Ubiquitin_40,Uba1,E1_Ubiquitin,P0CG63,1.0168,NO,40,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-1.48,-3.087,1.607,,0.387,G,A,,0.03,,,,OPP,-1.365,0.18783,0.0037961,1.0168 E1_Ubiquitin_Q41I,E1_Ubiquitin_41,Uba1,E1_Ubiquitin,P0CG63,1.0168,NO,41,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-1.25,-3.827,2.577,,0.017,E,B,,-0.98,,,,PPB,-1.344,0.18783,0.00215097,1.0168 E1_Ubiquitin_Q41Q,E1_Ubiquitin_41,Uba1,E1_Ubiquitin,P0CG63,1.0168,NO,41,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-1.25,-1.25,,,0.017,E,B,,-0.98,,,,PPB,-1.344,0.18783,0.00215097,1.0168 kka2_1:1_I141Q,kka2_1:1_141,Kka2,kka2_1:1,P00552,1.0168,NO,141,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.495,-4.325,2.83,,0.068,H,A,0.48,-0.01,7.546,7.546,92.05,BHA,-1.689,0.520039,0.00744745,1.0168 kka2_1:4_D134S,kka2_1:4_134,Kka2,kka2_1:4,P00552,1.0168,NO,134,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.969,-2.62,1.651,,0.421,B,B,0.75,0.31,0.733,,49.62,HAB,-1.057,0.168804,0.00270812,1.0168 beta-lactamase_156_M180S,beta-lactamase_156_180,TEM-1,beta-lactamase_156,P62593,1.01681,NO,180,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-2.795,-2.032,-0.763,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.111618,0.00552048,1.01681 beta-lactamase_625_A84K,beta-lactamase_625_84,TEM-1,beta-lactamase_625,P62593,1.01681,NO,84,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.651,-2.484,0.833,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.213352,0.00503822,1.01681 beta-lactamase_39_P65K,beta-lactamase_39_65,TEM-1,beta-lactamase_39,P62593,1.01682,NO,65,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.894,-3.511,2.617,,0.098,E,B,0.52,-0.62,0.623,,40.56,HOH,-1.03233,0.0495842,0.00152776,1.01682 beta-lactamase_A9P,beta-lactamase_9,TEM-1,beta-lactamase,P62593,1.01684,NO,9,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.147,-2.864,0.717,,,,,,,5.128,,72.73,HHH,-2.04267,0.221079,0.00247263,1.01684 beta-lactamase_0_A183L,beta-lactamase_0_183,TEM-1,beta-lactamase_0,P62593,1.01685,NO,183,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.231,-3.283,2.052,,0.155,H,A,0.46,-0.91,1.48,,77.62,HHH,-1.53367,0.0500837,0.00296631,1.01685 beta-lactamase_39_L38D,beta-lactamase_39_38,TEM-1,beta-lactamase_39,P62593,1.01685,NO,38,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.343,-3.97,2.627,,0.088,H,A,0.55,0.2,17.089,17.089,64.34,PHO,-1.78033,0.0495842,0.00373244,1.01685 beta-lactamase_156_A84W,beta-lactamase_156_84,TEM-1,beta-lactamase_156,P62593,1.01686,NO,84,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.651,-5.52,3.869,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.111618,0.00503822,1.01686 beta-lactamase_39_F70T,beta-lactamase_39_70,TEM-1,beta-lactamase_39,P62593,1.01686,NO,70,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.169,-3.571,2.402,,,H,A,0.58,-1.34,1.14,,63.99,PHB,-0.980667,0.0495842,0.00193499,1.01686 PSD95pdz3_V386A,PSD95pdz3_386,PSD95pdz3,PSD95pdz3,P31016,1.01686,NO,386,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.465,-2.534,1.069,5.18836,,,,,17.5429,,,,PHP,-1.463,0.0758425,0.000184509,1.01686 beta-lactamase_0_P25D,beta-lactamase_0_25,TEM-1,beta-lactamase_0,P62593,1.01687,NO,25,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.526,-2.562,1.036,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.0500837,0.00347571,1.01687 beta-lactamase_625_E108G,beta-lactamase_625_108,TEM-1,beta-lactamase_625,P62593,1.01688,NO,108,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.46,-2.454,0.994,,0.572,G,A,1.04,1.87,20.151,20.151,72.73,PAB,-1.437,0.213352,0.00413372,1.01688 beta-lactamase_156_I54Y,beta-lactamase_156_54,TEM-1,beta-lactamase_156,P62593,1.01689,NO,54,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-2.838,-4.264,1.426,,0.669,E,B,0.48,-0.14,0.541,,73.78,BHH,-2.337,0.111618,0.00403589,1.01689 PSD95pdz3_G333L,PSD95pdz3_333,PSD95pdz3,PSD95pdz3,P31016,1.0169,NO,333,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.008,-3.49,2.482,5.09445,,,,,48.755,,,,AOA,-1.22533,0.0758425,0.00092544,1.0169 beta-lactamase_2500_R202Q,beta-lactamase_2500_202,TEM-1,beta-lactamase_2500,P62593,1.01691,NO,202,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.292,-1.95,0.658,,0.188,H,A,1.2,0.62,3.734,,77.62,PBP,-1.54767,0.361275,0.00321899,1.01691 beta-lactamase_D36I,beta-lactamase_36,TEM-1,beta-lactamase,P62593,1.01691,NO,36,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.732,-4.112,1.38,5.39764,0.555,H,A,0.11,1.17,13.689,13.689,77.62,AAP,-1.91167,0.221079,0.00476483,1.01691 kka2_1:8_T72I,kka2_1:8_72,Kka2,kka2_1:8,P00552,1.01691,NO,72,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.38,-4.117,1.737,,0.784,H,A,0.22,0.29,3.603,,65.53,HPP,-2.238,0.100394,0.00750756,1.01691 kka2_1:8_T72I,kka2_1:8_72,Kka2,kka2_1:8,P00552,1.01691,NO,72,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.38,-4.117,1.737,,0.784,H,A,0.22,0.29,3.603,,65.53,HPP,-2.238,0.100394,0.00750756,1.01691 PSD95pdz3_Y392W,PSD95pdz3_392,PSD95pdz3,PSD95pdz3,P31016,1.01691,NO,392,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-1.437,-3.879,2.442,5.20337,,,,,11.725,,,,PHB,-1.51733,0.0758425,0.000935211,1.01691 beta-lactamase_39_G194H,beta-lactamase_39_194,TEM-1,beta-lactamase_39,P62593,1.01692,NO,194,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.396,-4.628,3.232,,0.276,S,b,0.29,0.36,4.852,,67.83,POA,-1.832,0.0495842,0.00392163,1.01692 beta-lactamase_625_A183Q,beta-lactamase_625_183,TEM-1,beta-lactamase_625,P62593,1.01692,NO,183,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.231,-3.932,2.701,,0.155,H,A,0.46,-0.91,23.859,23.859,77.62,HHH,-1.53367,0.213352,0.00296631,1.01692 beta-lactamase_39_F70V,beta-lactamase_39_70,TEM-1,beta-lactamase_39,P62593,1.01693,NO,70,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.169,-2.579,1.41,,,H,A,0.58,-1.34,1.14,,63.99,PHB,-0.980667,0.0495842,0.00193499,1.01693 beta-lactamase_39_T126D,beta-lactamase_39_126,TEM-1,beta-lactamase_39,P62593,1.01693,NO,126,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.122,-2.344,1.222,,0.05,H,A,0.22,-0.05,0.586,,44.41,HPH,-1.60467,0.0495842,0.00244552,1.01693 beta-lactamase_625_E87T,beta-lactamase_625_87,TEM-1,beta-lactamase_625,P62593,1.01693,NO,87,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.421,-2.787,1.366,,0.048,,B,1.04,0.92,17.923,17.923,64.69,PAP,-1.969,0.213352,0.00337888,1.01693 beta-lactamase_39_A246C,beta-lactamase_39_246,TEM-1,beta-lactamase_39,P62593,1.01694,NO,246,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.121,-3.242,1.121,,0.01,E,B,0.46,-1.01,1.331,,73.78,HHH,-1.55633,0.0495842,0.00569458,1.01694 beta-lactamase_39_G85K,beta-lactamase_39_85,TEM-1,beta-lactamase_39,P62593,1.01695,NO,85,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.011,-2.219,1.208,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.0495842,0.00252173,1.01695 beta-lactamase_D113D,beta-lactamase_113,TEM-1,beta-lactamase,P62593,1.01695,NO,113,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.829,-1.829,,6.04499,0.665,T,A,0.23,0.91,21.104,21.104,73.08,PAO,-1.703,0.221079,0.00474112,1.01695 kka2_1:2_R44H,kka2_1:2_44,Kka2,kka2_1:2,P00552,1.01695,NO,44,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.062,-3.488,1.426,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.295029,0.00745043,1.01695 beta-lactamase_625_K109L,beta-lactamase_625_109,TEM-1,beta-lactamase_625,P62593,1.01698,NO,109,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.734,-2.969,1.235,,0.787,G,A,2.34,2.21,7.243,,72.73,ABB,-1.63333,0.213352,0.00462493,1.01698 beta-lactamase_156_I280L,beta-lactamase_156_280,TEM-1,beta-lactamase_156,P62593,1.01699,NO,280,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.111618,0.0530888,1.01699 kka2_1:2_M197L,kka2_1:2_197,Kka2,kka2_1:2,P00552,1.017,NO,197,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.707,-1.777,0.07,,0.121,E,B,0.55,-1.19,2.097,,65.53,HHH,-1.847,0.295029,0.00921295,1.017 Pab1_L190A,Pab1_190,Pab1,Pab1,P04147,1.017,NO,190,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.325,-2.913,1.588,,0.489,E,B,,2.59,,,,HHH,-1.31033,0.175299,0.00132347,1.017 beta-lactamase_625_K53N,beta-lactamase_625_53,TEM-1,beta-lactamase_625,P62593,1.01701,NO,53,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-2.313,-3.809,1.496,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.213352,0.00383383,1.01701 beta-lactamase_156_A230I,beta-lactamase_156_230,TEM-1,beta-lactamase_156,P62593,1.01702,NO,230,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.154,-3.843,2.689,,0.01,E,B,0.46,-1.17,2.179,,50,HHA,-1.079,0.111618,0.00516841,1.01702 PSD95pdz3_N363S,PSD95pdz3_363,PSD95pdz3,PSD95pdz3,P31016,1.01702,NO,363,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-1.41,-2.617,1.207,5.23349,,,,,20.7037,,,,HPO,-1.29433,0.0758425,0.000524014,1.01702 beta-lactamase_0_S241R,beta-lactamase_0_241,TEM-1,beta-lactamase_0,P62593,1.01703,NO,241,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.433,-3.314,1.881,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.0500837,0.00452736,1.01703 beta-lactamase_625_T186I,beta-lactamase_625_186,TEM-1,beta-lactamase_625,P62593,1.01703,NO,186,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.522,-3.94,1.418,,0.396,H,A,0.22,-0.28,0.515,,77.62,HPP,-1.77633,0.213352,0.00485034,1.01703 beta-lactamase_H156Y,beta-lactamase_156,TEM-1,beta-lactamase,P62593,1.01703,NO,156,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-3.156,-4.359,1.203,6.00284,0.753,S,A,0.72,-0.6,6.456,6.456,77.62,ABH,-1.932,0.221079,0.00468596,1.01703 beta-lactamase_156_K286H,beta-lactamase_156_286,TEM-1,beta-lactamase_156,P62593,1.01705,NO,286,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.111618,,1.01705 beta-lactamase_156_T112I,beta-lactamase_156_112,TEM-1,beta-lactamase_156,P62593,1.01705,NO,112,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.186,-3.949,1.763,,0.921,T,A,0.22,1.06,2.87,,73.78,HPA,-1.925,0.111618,0.00531334,1.01705 beta-lactamase_39_G154C,beta-lactamase_39_154,TEM-1,beta-lactamase_39,P62593,1.01706,NO,154,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.823,-5.058,4.235,,0.54,T,l,0.29,-0.56,1.151,,64.69,HOA,-1.635,0.0495842,0.00180205,1.01706 beta-lactamase_39_G90N,beta-lactamase_39_90,TEM-1,beta-lactamase_39,P62593,1.01706,NO,90,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-2.091,-2.941,0.85,,0.598,T,A,0.29,0.32,30.794,30.794,77.62,HOB,-1.52633,0.0495842,0.00490273,1.01706 beta-lactamase_E166D,beta-lactamase_166,TEM-1,beta-lactamase,P62593,1.01706,NO,166,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.756,-2.259,0.503,5.60527,0.508,G,A,0.52,1.05,2.124,,73.08,OAH,-1.42233,0.221079,0.00512989,1.01706 beta-lactamase_T186V,beta-lactamase_186,TEM-1,beta-lactamase,P62593,1.01706,NO,186,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.522,-3.557,1.035,5.07364,0.396,H,A,0.3,-0.28,2.144,,77.62,HPP,-1.77633,0.221079,0.00485034,1.01706 beta-lactamase_625_M127N,beta-lactamase_625_127,TEM-1,beta-lactamase_625,P62593,1.01707,NO,127,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-2.251,-4.047,1.796,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.213352,0.00437927,1.01707 beta-lactamase_2500_T186G,beta-lactamase_2500_186,TEM-1,beta-lactamase_2500,P62593,1.01708,NO,186,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.522,-2.403,-0.119,,0.396,H,A,0.22,-0.28,2.144,,77.62,HPP,-1.77633,0.361275,0.00485034,1.01708 beta-lactamase_625_R189K,beta-lactamase_625_189,TEM-1,beta-lactamase_625,P62593,1.01709,NO,189,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.844,-2.391,0.547,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.213352,0.0050699,1.01709 beta-lactamase_2500_L188I,beta-lactamase_2500_188,TEM-1,beta-lactamase_2500,P62593,1.0171,NO,188,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.166,-2.584,1.418,,,H,A,0.55,-0.3,17.865,17.865,60.14,PHB,-1.47033,0.361275,0.00295687,1.0171 beta-lactamase_2500_R118A,beta-lactamase_2500_118,TEM-1,beta-lactamase_2500,P62593,1.0171,NO,118,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.413,-1.798,-0.615,,0.457,H,A,1.2,1.39,2.144,,77.62,HBA,-1.785,0.361275,0.00538794,1.0171 beta-lactamase_625_L223I,beta-lactamase_625_223,TEM-1,beta-lactamase_625,P62593,1.01711,NO,223,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.055,-2.996,1.941,,0.27,,B,0.55,0.09,1.633,,74.48,HHO,-1.35033,0.213352,0.00372793,1.01711 beta-lactamase_39_T126I,beta-lactamase_39_126,TEM-1,beta-lactamase_39,P62593,1.01712,NO,126,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.122,-3.78,2.658,,0.05,H,A,0.22,-0.05,0.586,,44.41,HPH,-1.60467,0.0495842,0.00244552,1.01712 beta-lactamase_R238M,beta-lactamase_238,TEM-1,beta-lactamase,P62593,1.01712,NO,238,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.002,-4.704,2.702,5.87663,0.564,T,L,0.45,1.09,4.195,,72.73,ABO,-1.62633,0.221079,0.00743256,1.01712 beta-lactamase_S96S,beta-lactamase_96,TEM-1,beta-lactamase,P62593,1.01712,NO,96,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.27,-2.27,,5.29889,0.368,,b,0.25,0.39,32.348,32.348,73.78,HPP,-2.019,0.221079,0.00551835,1.01712 PSD95pdz3_A382G,PSD95pdz3_382,PSD95pdz3,PSD95pdz3,P31016,1.01713,NO,382,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.307,-2.59,1.283,5.30282,,,,,22.472,,,,PHO,-1.24167,0.0758425,0.000249256,1.01713 beta-lactamase_2500_Q267N,beta-lactamase_2500_267,TEM-1,beta-lactamase_2500,P62593,1.01714,NO,267,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.361275,0.0102128,1.01714 kka2_1:2_C77G,kka2_1:2_77,Kka2,kka2_1:2,P00552,1.01714,NO,77,C,G,CG,Special,Special,5.07,3.29388,-1.77612,159,121,75,-46,108.5,60.1,-48.4,-1.477,-2.097,0.62,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.295029,0.00441216,1.01714 beta-lactamase_39_G141E,beta-lactamase_39_141,TEM-1,beta-lactamase_39,P62593,1.01715,NO,141,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.828,-2.606,1.778,,0.575,T,l,0.29,-0.28,0.722,,64.69,HOO,-1.08933,0.0495842,0.0012419,1.01715 beta-lactamase_0_Q267V,beta-lactamase_0_267,TEM-1,beta-lactamase_0,P62593,1.01716,NO,267,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.0500837,0.0102128,1.01716 beta-lactamase_39_E145D,beta-lactamase_39_145,TEM-1,beta-lactamase_39,P62593,1.01716,NO,145,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.357,-3.52,1.163,,0.545,H,A,1.04,0.79,1.199,,77.62,BAH,-2.069,0.0495842,0.00553285,1.01716 PSD95pdz3_Q391S,PSD95pdz3_391,PSD95pdz3,PSD95pdz3,P31016,1.01717,NO,391,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-1.699,-2.842,1.143,5.50275,,,,,12.6589,,,,HPH,-1.481,0.0758425,0.000990786,1.01717 beta-lactamase_156_T69P,beta-lactamase_156_69,TEM-1,beta-lactamase_156,P62593,1.01718,NO,69,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-0.973,-3.715,2.742,,,G,A,0.22,-1.24,4.194,,93.01,PPH,-1.01833,0.111618,0.00127498,1.01718 beta-lactamase_39_R92V,beta-lactamase_39_92,TEM-1,beta-lactamase_39,P62593,1.01718,NO,92,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.718,-2.509,0.791,,0.479,E,B,1.2,1.36,0.389,,65.38,BBH,-1.50367,0.0495842,0.00429626,1.01718 kka2_1:1_R121D,kka2_1:1_121,Kka2,kka2_1:1,P00552,1.01718,NO,121,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.552,-3.714,2.162,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.520039,0.00523326,1.01718 beta-lactamase_156_A84T,beta-lactamase_156_84,TEM-1,beta-lactamase_156,P62593,1.01719,NO,84,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.651,-2.88,1.229,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.111618,0.00503822,1.01719 beta-lactamase_39_R91K,beta-lactamase_39_91,TEM-1,beta-lactamase_39,P62593,1.01719,NO,91,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.392,-2.505,1.113,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.0495842,0.00380226,1.01719 beta-lactamase_39_A235K,beta-lactamase_39_235,TEM-1,beta-lactamase_39,P62593,1.0172,NO,235,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.266,-3.575,2.309,,0.32,E,B,0.46,-0.86,1.344,,50,OHO,-0.89,0.0495842,0.00493474,1.0172 beta-lactamase_39_D174R,beta-lactamase_39_174,TEM-1,beta-lactamase_39,P62593,1.0172,NO,174,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.738,-3.933,3.195,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.0495842,0.00125633,1.0172 beta-lactamase_39_E279N,beta-lactamase_39_279,TEM-1,beta-lactamase_39,P62593,1.0172,NO,279,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.0495842,0.0192826,1.0172 beta-lactamase_625_E46V,beta-lactamase_625_46,TEM-1,beta-lactamase_625,P62593,1.0172,NO,46,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.94,-1.834,-0.106,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.213352,0.00427568,1.0172 beta-lactamase_156_D271L,beta-lactamase_156_271,TEM-1,beta-lactamase_156,P62593,1.01721,NO,271,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.111618,0.00752082,1.01721 beta-lactamase_39_L197A,beta-lactamase_39_197,TEM-1,beta-lactamase_39,P62593,1.01721,NO,197,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.853,-2.357,1.504,,0.007,S,B,0.55,0.33,1.559,,60.14,HHP,-1.833,0.0495842,0.00144602,1.01721 beta-lactamase_39_R92F,beta-lactamase_39_92,TEM-1,beta-lactamase_39,P62593,1.01721,NO,92,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.718,-4.33,2.612,,0.479,E,B,1.2,1.36,0.389,,65.38,BBH,-1.50367,0.0495842,0.00429626,1.01721 kka2_1:1_L184Q,kka2_1:1_184,Kka2,kka2_1:1,P00552,1.01721,NO,184,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.496,-4.197,2.701,,0.489,E,B,0.55,-0.06,19.127,19.127,63.26,AHH,-1.24833,0.520039,0.00518742,1.01721 kka2_1:4_E235P,kka2_1:4_235,Kka2,kka2_1:4,P00552,1.01721,NO,235,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.955,-2.919,0.964,,0.631,H,A,1.04,0.12,23.175,23.175,65.53,OAH,-2.07267,0.168804,0.0102806,1.01721 kka2_1:8_L243Y,kka2_1:8_243,Kka2,kka2_1:8,P00552,1.01721,NO,243,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-2.651,-4.342,1.691,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.100394,0.00884927,1.01721 kka2_1:8_L243Y,kka2_1:8_243,Kka2,kka2_1:8,P00552,1.01721,NO,243,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-2.651,-4.342,1.691,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.100394,0.00884927,1.01721 beta-lactamase_156_G114F,beta-lactamase_156_114,TEM-1,beta-lactamase_156,P62593,1.01722,NO,114,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.094,-4.331,3.237,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.111618,0.00224919,1.01722 beta-lactamase_156_V29Q,beta-lactamase_156_29,TEM-1,beta-lactamase_156,P62593,1.01722,NO,29,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-2.856,-2.926,0.07,,0.733,H,A,0.44,-0.78,3.685,,93.01,HHB,-2.24733,0.111618,0.00318969,1.01722 beta-lactamase_2500_E166H,beta-lactamase_2500_166,TEM-1,beta-lactamase_2500,P62593,1.01722,NO,166,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.756,-4.668,2.912,,0.508,G,A,1.04,1.05,2.124,,73.08,OAH,-1.42233,0.361275,0.00512989,1.01722 beta-lactamase_V106I,beta-lactamase_106,TEM-1,beta-lactamase,P62593,1.01722,NO,106,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.218,-2.124,0.906,5.23115,0.258,T,A,0.96,0.24,1.188,,72.73,OHP,-1.04933,0.221079,0.00304168,1.01722 gb1_T243Y,gb1_243,gb1,gb1,P06654,1.01723,NO,243,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.415,-3.973,2.558,,,,,,,1.083,,37.28,PPP,-1.43233,0.177985,0.00308687,1.01723 beta-lactamase_156_H110G,beta-lactamase_156_110,TEM-1,beta-lactamase_156,P62593,1.01724,NO,110,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-1.706,-3.573,1.867,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.111618,0.00441499,1.01724 beta-lactamase_39_A247N,beta-lactamase_39_247,TEM-1,beta-lactamase_39,P62593,1.01724,NO,247,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.0495842,0.00611275,1.01724 beta-lactamase_39_I245L,beta-lactamase_39_245,TEM-1,beta-lactamase_39,P62593,1.01724,NO,245,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.0495842,0.00391032,1.01724 beta-lactamase_I45V,beta-lactamase_45,TEM-1,beta-lactamase,P62593,1.01724,NO,45,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-2.421,-2.178,-0.243,5.31505,,E,B,1,-0.3,2.256,,77.62,HHA,-2.30267,0.221079,0.00452842,1.01724 beta-lactamase_156_E35S,beta-lactamase_156_35,TEM-1,beta-lactamase_156,P62593,1.01725,NO,35,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-0.869,-3.186,2.317,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.111618,0.00174441,1.01725 beta-lactamase_K144A,beta-lactamase_144,TEM-1,beta-lactamase,P62593,1.01726,NO,144,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-2.388,-2.013,-0.375,6.02507,0.863,H,A,2.81,1.27,0.515,,77.62,OBA,-1.904,0.221079,0.00481141,1.01726 beta-lactamase_39_P172N,beta-lactamase_39_172,TEM-1,beta-lactamase_39,P62593,1.01727,NO,172,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.998,-3.875,2.877,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.0495842,0.00312594,1.01727 beta-lactamase_39_T112C,beta-lactamase_39_112,TEM-1,beta-lactamase_39,P62593,1.01729,NO,112,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.186,-5.027,2.841,,0.921,T,A,0.22,1.06,2.87,,73.78,HPA,-1.925,0.0495842,0.00531334,1.01729 beta-lactamase_39_S233P,beta-lactamase_39_233,TEM-1,beta-lactamase_39,P62593,1.0173,NO,233,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.886,-2.778,0.892,,0.016,E,B,0.27,-1.01,5.361,,77.62,BPO,-1.17267,0.0495842,0.00311415,1.0173 beta-lactamase_625_K32F,beta-lactamase_625_32,TEM-1,beta-lactamase_625,P62593,1.0173,NO,32,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.984,-4.328,2.344,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.213352,0.00401283,1.0173 Pab1_Q194A,Pab1_194,Pab1,Pab1,P04147,1.0173,NO,194,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.179,-3.166,0.987,,,,,,,,,,OPA,-1.59767,0.175299,0.0016145,1.0173 beta-lactamase_156_S283Q,beta-lactamase_156_283,TEM-1,beta-lactamase_156,P62593,1.01731,NO,283,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.111618,0.0429138,1.01731 beta-lactamase_39_A182G,beta-lactamase_39_182,TEM-1,beta-lactamase_39,P62593,1.01731,NO,182,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.777,-3.408,1.631,,0.136,H,A,0.46,-0.66,2.598,,93.01,OHH,-1.27367,0.0495842,0.00559099,1.01731 beta-lactamase_39_W163I,beta-lactamase_39_163,TEM-1,beta-lactamase_39,P62593,1.01731,NO,163,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-1.843,-3.136,1.293,,0.467,,B,0.47,-0.5,15.095,15.095,63.99,BHA,-1.269,0.0495842,0.00418955,1.01731 beta-lactamase_156_P255M,beta-lactamase_156_255,TEM-1,beta-lactamase_156,P62593,1.01732,NO,255,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.111618,0.00499612,1.01732 beta-lactamase_39_T138C,beta-lactamase_39_138,TEM-1,beta-lactamase_39,P62593,1.01732,NO,138,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.506,-5.125,2.619,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.0495842,0.00487868,1.01732 kka2_1:2_V16F,kka2_1:2_16,Kka2,kka2_1:2,P00552,1.01732,NO,16,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-3.087,-4.39,1.303,,0.742,T,A,0.44,0.34,1.746,,71.59,HHA,-2.211,0.295029,0.00694011,1.01732 kka2_1:4_M1V,kka2_1:4_1,Kka2,kka2_1:4,P00552,1.01732,NO,1,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.787,-1.867,0.08,,,,,,,1.347,,62.12,NAHH,-1.787,0.168804,0.00251939,1.01732 beta-lactamase_156_I206M,beta-lactamase_156_206,TEM-1,beta-lactamase_156,P62593,1.01733,NO,206,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-2.429,-3.069,0.64,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.111618,0.00528934,1.01733 beta-lactamase_39_A84I,beta-lactamase_39_84,TEM-1,beta-lactamase_39,P62593,1.01733,NO,84,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.651,-3.932,2.281,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.0495842,0.00503822,1.01733 beta-lactamase_39_N130D,beta-lactamase_39_130,TEM-1,beta-lactamase_39,P62593,1.01733,NO,130,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-0.798,-3.019,2.221,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.0495842,0.000683376,1.01733 beta-lactamase_625_R92K,beta-lactamase_625_92,TEM-1,beta-lactamase_625,P62593,1.01733,NO,92,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.718,-2.258,0.54,,0.479,E,B,1.2,1.36,3.069,,65.38,BBH,-1.50367,0.213352,0.00429626,1.01733 beta-lactamase_R189Q,beta-lactamase_189,TEM-1,beta-lactamase,P62593,1.01733,NO,189,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.844,-2.262,0.418,5.74877,0.278,H,A,0.68,1.01,1.512,,72.73,HBB,-1.668,0.221079,0.0050699,1.01733 beta-lactamase_156_K144F,beta-lactamase_156_144,TEM-1,beta-lactamase_156,P62593,1.01734,NO,144,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-2.388,-4.427,2.039,,0.863,H,A,2.34,1.27,2.073,,77.62,OBA,-1.904,0.111618,0.00481141,1.01734 beta-lactamase_39_E145G,beta-lactamase_39_145,TEM-1,beta-lactamase_39,P62593,1.01734,NO,145,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.357,-1.279,-1.078,,0.545,H,A,1.04,0.79,1.199,,77.62,BAH,-2.069,0.0495842,0.00553285,1.01734 beta-lactamase_625_I245M,beta-lactamase_625_245,TEM-1,beta-lactamase_625,P62593,1.01734,NO,245,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.213352,0.00391032,1.01734 beta-lactamase_39_G240T,beta-lactamase_39_240,TEM-1,beta-lactamase_39,P62593,1.01735,NO,240,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.0495842,0.00591201,1.01735 beta-lactamase_39_S256E,beta-lactamase_39_256,TEM-1,beta-lactamase_39,P62593,1.01735,NO,256,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.0495842,0.00710634,1.01735 beta-lactamase_625_L223T,beta-lactamase_625_223,TEM-1,beta-lactamase_625,P62593,1.01735,NO,223,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.055,-2.595,1.54,,0.27,,B,0.55,0.09,1.633,,74.48,HHO,-1.35033,0.213352,0.00372793,1.01735 beta-lactamase_2500_V259I,beta-lactamase_2500_259,TEM-1,beta-lactamase_2500,P62593,1.01736,NO,259,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.522,-1.739,0.217,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.361275,0.0070773,1.01736 kka2_1:8_D180Q,kka2_1:8_180,Kka2,kka2_1:8,P00552,1.01736,NO,180,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.416,-3.007,0.591,,1.03,S,a,0.75,1.5,14.668,14.668,71.59,OAO,-2.02933,0.100394,0.00756412,1.01736 kka2_1:8_D180Q,kka2_1:8_180,Kka2,kka2_1:8,P00552,1.01736,NO,180,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.416,-3.007,0.591,,1.03,S,a,0.75,1.5,14.668,14.668,71.59,OAO,-2.02933,0.100394,0.00756412,1.01736 Pab1_E175E,Pab1_175,Pab1,Pab1,P04147,1.01736,NO,175,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.055,-2.055,,,,,,,,,,,AAA,-1.82667,0.175299,0.00203137,1.01736 beta-lactamase_N173D,beta-lactamase_173,TEM-1,beta-lactamase,P62593,1.01737,NO,173,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-2.663,-2.368,-0.295,7.02497,1.044,T,l,0.09,1.25,1.88,,77.62,OPA,-1.46633,0.221079,0.0033769,1.01737 gb1_Y229W,gb1_229,gb1,gb1,P06654,1.01737,NO,229,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-1.282,-3.933,2.651,,,,,,,,,,PHB,-1.4915,0.177985,0.00366605,1.01737 beta-lactamase_0_A200R,beta-lactamase_0_200,TEM-1,beta-lactamase_0,P62593,1.01739,NO,200,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.878,-2.634,0.756,,0.757,H,A,0.46,-0.19,16.368,16.368,77.62,HHP,-2.001,0.0500837,0.0060056,1.01739 beta-lactamase_0_G236Y,beta-lactamase_0_236,TEM-1,beta-lactamase_0,P62593,1.01739,NO,236,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.784,-4.387,3.603,,0.241,,b,0.29,-0.59,3.506,,64.69,HOO,-1.025,0.0500837,0.00162372,1.01739 beta-lactamase_39_M270K,beta-lactamase_39_270,TEM-1,beta-lactamase_39,P62593,1.01739,NO,270,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.0495842,0.00767762,1.01739 beta-lactamase_39_M270W,beta-lactamase_39_270,TEM-1,beta-lactamase_39,P62593,1.01739,NO,270,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.0495842,0.00767762,1.01739 beta-lactamase_K53N,beta-lactamase_53,TEM-1,beta-lactamase,P62593,1.01739,NO,53,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-2.313,-3.809,1.496,5.93654,0.589,,B,1.82,1.15,19.72,19.72,77.62,OBH,-2.1,0.221079,0.00383383,1.01739 kka2_1:2_R44M,kka2_1:2_44,Kka2,kka2_1:2,P00552,1.0174,NO,44,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.062,-4.711,2.649,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.295029,0.00745043,1.0174 beta-lactamase_G141G,beta-lactamase_141,TEM-1,beta-lactamase,P62593,1.01741,NO,141,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.828,-0.828,,5.03155,0.575,T,l,0.76,-0.28,0.198,,64.69,HOO,-1.08933,0.221079,0.0012419,1.01741 kka2_1:2_G151E,kka2_1:2_151,Kka2,kka2_1:2,P00552,1.01741,NO,151,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.873,-3.557,2.684,,0.678,T,l,0.29,1.36,1.357,,49.62,HOH,-1.11433,0.295029,0.00339918,1.01741 beta-lactamase_A200Q,beta-lactamase_200,TEM-1,beta-lactamase,P62593,1.01743,NO,200,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.878,-3.113,1.235,5.19406,0.757,H,A,0.47,-0.19,0.436,,77.62,HHP,-2.001,0.221079,0.0060056,1.01743 beta-lactamase_39_R275L,beta-lactamase_39_275,TEM-1,beta-lactamase_39,P62593,1.01744,NO,275,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.0495842,0.0141984,1.01744 beta-lactamase_625_F70V,beta-lactamase_625_70,TEM-1,beta-lactamase_625,P62593,1.01744,NO,70,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.169,-2.579,1.41,,,H,A,0.58,-1.34,1.14,,63.99,PHB,-0.980667,0.213352,0.00193499,1.01744 PSD95pdz3_I377V,PSD95pdz3_377,PSD95pdz3,PSD95pdz3,P31016,1.01744,NO,377,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.873,-1.947,0.074,4.9532,,,,,19.185,2.364,,87.71,HHH,-1.49567,0.0758425,0.000795475,1.01744 beta-lactamase_625_S221T,beta-lactamase_625_221,TEM-1,beta-lactamase_625,P62593,1.01745,NO,221,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.754,-3.292,1.538,,0.624,H,A,0.27,-0.2,1.495,,74.48,BPH,-1.59967,0.213352,0.0046094,1.01745 beta-lactamase_625_V117M,beta-lactamase_625_117,TEM-1,beta-lactamase_625,P62593,1.01745,NO,117,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.53,-3.063,1.533,,,H,A,0.44,-0.34,1.23,,65.03,PHB,-1.741,0.213352,0.00467906,1.01745 beta-lactamase_156_G154N,beta-lactamase_156_154,TEM-1,beta-lactamase_156,P62593,1.01746,NO,154,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.823,-3.507,2.684,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.111618,0.00180205,1.01746 beta-lactamase_39_G85M,beta-lactamase_39_85,TEM-1,beta-lactamase_39,P62593,1.01746,NO,85,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.011,-4.877,3.866,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.0495842,0.00252173,1.01746 kka2_1:2_L243K,kka2_1:2_243,Kka2,kka2_1:2,P00552,1.01746,NO,243,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-2.651,-3.021,0.37,,0.277,H,A,1.59,-0.67,13.165,13.165,92.05,HHH,-2.03767,0.295029,0.00884927,1.01746 beta-lactamase_V8T,beta-lactamase_8,TEM-1,beta-lactamase,P62593,1.01747,NO,8,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-2.358,-3.423,1.065,,,,,,,0.575,,77.62,BHH,-2.06267,0.221079,0.00226401,1.01747 PSD95pdz3_G383Q,PSD95pdz3_383,PSD95pdz3,PSD95pdz3,P31016,1.01747,NO,383,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.008,-3.806,2.798,5.17213,,,,,20.5325,,,,HOP,-1.338,0.0758425,0.000233044,1.01747 kka2_1:2_R18T,kka2_1:2_18,Kka2,kka2_1:2,P00552,1.01748,NO,18,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.055,-2.928,0.873,,0.474,T,A,1.2,0.54,8.405,8.405,71.59,ABH,-1.821,0.295029,0.00724065,1.01748 beta-lactamase_156_A211P,beta-lactamase_156_211,TEM-1,beta-lactamase_156,P62593,1.0175,NO,211,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.896,-3.94,2.044,,0.369,T,A,0.46,-0.69,8.527,8.527,77.62,AHA,-1.94633,0.111618,0.00648183,1.0175 beta-lactamase_156_E108R,beta-lactamase_156_108,TEM-1,beta-lactamase_156,P62593,1.0175,NO,108,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.46,-2.885,1.425,,0.572,G,A,1.04,1.87,8.602,8.602,72.73,PAB,-1.437,0.111618,0.00413372,1.0175 beta-lactamase_156_I258V,beta-lactamase_156_258,TEM-1,beta-lactamase_156,P62593,1.0175,NO,258,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.975,-2.547,0.572,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.111618,0.007931,1.0175 beta-lactamase_156_S201C,beta-lactamase_156_201,TEM-1,beta-lactamase_156,P62593,1.01752,NO,201,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.183,-4.753,3.57,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.111618,0.00198815,1.01752 beta-lactamase_625_E195A,beta-lactamase_625_195,TEM-1,beta-lactamase_625,P62593,1.01752,NO,195,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.186,-2.778,0.592,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.213352,0.00496565,1.01752 beta-lactamase_0_T147F,beta-lactamase_0_147,TEM-1,beta-lactamase_0,P62593,1.01753,NO,147,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.149,-4.147,2.998,,0.281,H,A,0.22,-0.68,3.487,,64.34,HPH,-1.456,0.0500837,0.00226017,1.01753 beta-lactamase_156_T112V,beta-lactamase_156_112,TEM-1,beta-lactamase_156,P62593,1.01753,NO,112,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.186,-2.929,0.743,,0.921,T,A,0.22,1.06,2.87,,73.78,HPA,-1.925,0.111618,0.00531334,1.01753 beta-lactamase_156_I285Q,beta-lactamase_156_285,TEM-1,beta-lactamase_156,P62593,1.01757,NO,285,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.111618,0.101555,1.01757 beta-lactamase_156_K109I,beta-lactamase_156_109,TEM-1,beta-lactamase_156,P62593,1.01758,NO,109,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.734,-4.102,2.368,,0.787,G,A,2.34,2.21,6.031,,72.73,ABB,-1.63333,0.111618,0.00462493,1.01758 beta-lactamase_39_L205E,beta-lactamase_39_205,TEM-1,beta-lactamase_39,P62593,1.01758,NO,205,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.922,-3.908,2.986,,,H,A,0.55,-0.46,0.846,,42.31,PHH,-1.57767,0.0495842,0.00255802,1.01758 beta-lactamase_39_T263A,beta-lactamase_39_263,TEM-1,beta-lactamase_39,P62593,1.01758,NO,263,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.0495842,0.0110582,1.01758 beta-lactamase_625_L188I,beta-lactamase_625_188,TEM-1,beta-lactamase_625,P62593,1.01758,NO,188,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.166,-2.584,1.418,,,H,A,0.55,-0.3,2.982,,60.14,PHB,-1.47033,0.213352,0.00295687,1.01758 beta-lactamase_156_M67D,beta-lactamase_156_67,TEM-1,beta-lactamase_156,P62593,1.01759,NO,67,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-2.231,-3.779,1.548,,0.006,G,P,0.55,-0.81,1.463,,65.03,HHP,-1.502,0.111618,0.00409753,1.01759 beta-lactamase_625_H110W,beta-lactamase_625_110,TEM-1,beta-lactamase_625,P62593,1.01759,NO,110,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-1.706,-5.185,3.479,,0.341,G,a,0.17,1.08,31.31,31.31,64.69,BBH,-1.73333,0.213352,0.00441499,1.01759 beta-lactamase_E175M,beta-lactamase_175,TEM-1,beta-lactamase,P62593,1.01759,NO,175,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.336,-3.397,1.061,6.0311,0.551,,A,0.75,1.05,5.316,,77.62,AAB,-1.31233,0.221079,0.00482205,1.01759 beta-lactamase_39_G90A,beta-lactamase_39_90,TEM-1,beta-lactamase_39,P62593,1.0176,NO,90,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-2.091,-2.713,0.622,,0.598,T,A,0.29,0.32,30.794,30.794,77.62,HOB,-1.52633,0.0495842,0.00490273,1.0176 beta-lactamase_R238H,beta-lactamase_238,TEM-1,beta-lactamase,P62593,1.01761,NO,238,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.002,-1.973,-0.029,5.87663,0.564,T,L,0.45,1.09,4.195,,72.73,ABO,-1.62633,0.221079,0.00743256,1.01761 beta-lactamase_0_I277M,beta-lactamase_0_277,TEM-1,beta-lactamase_0,P62593,1.01762,NO,277,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.0500837,0.0169305,1.01762 beta-lactamase_625_R91M,beta-lactamase_625_91,TEM-1,beta-lactamase_625,P62593,1.01762,NO,91,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.392,-4.593,3.201,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.213352,0.00380226,1.01762 beta-lactamase_39_E238Y,beta-lactamase_39_238,TEM-1,beta-lactamase_39,P62593,1.01763,NO,238,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.0495842,0.00743256,1.01763 beta-lactamase_39_G43S,beta-lactamase_39_43,TEM-1,beta-lactamase_39,P62593,1.01763,NO,43,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.62,-3.161,2.541,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.0495842,0.00120151,1.01763 beta-lactamase_156_V29P,beta-lactamase_156_29,TEM-1,beta-lactamase_156,P62593,1.01764,NO,29,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-2.856,-3.853,0.997,,0.733,H,A,0.44,-0.78,3.685,,93.01,HHB,-2.24733,0.111618,0.00318969,1.01764 kka2_1:8_W24S,kka2_1:8_24,Kka2,kka2_1:8,P00552,1.01764,NO,24,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-1.779,-2.861,1.082,,0.477,E,B,1.51,-0.21,2.503,,56.06,AHH,-2.24467,0.100394,0.00631564,1.01764 kka2_1:8_W24S,kka2_1:8_24,Kka2,kka2_1:8,P00552,1.01764,NO,24,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-1.779,-2.861,1.082,,0.477,E,B,1.51,-0.21,2.503,,56.06,AHH,-2.24467,0.100394,0.00631564,1.01764 beta-lactamase_0_S201R,beta-lactamase_0_201,TEM-1,beta-lactamase_0,P62593,1.01765,NO,201,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.183,-3.779,2.596,,0.064,H,A,0.27,-0.07,3.54,,64.69,HPB,-1.451,0.0500837,0.00198815,1.01765 beta-lactamase_156_T186R,beta-lactamase_156_186,TEM-1,beta-lactamase_156,P62593,1.01765,NO,186,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.522,-2.819,0.297,,0.396,H,A,0.22,-0.28,16.606,16.606,77.62,HPP,-1.77633,0.111618,0.00485034,1.01765 beta-lactamase_39_D174C,beta-lactamase_39_174,TEM-1,beta-lactamase_39,P62593,1.01765,NO,174,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.738,-5.087,4.349,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.0495842,0.00125633,1.01765 PSD95pdz3_D332C,PSD95pdz3_332,PSD95pdz3,PSD95pdz3,P31016,1.01765,NO,332,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.264,-4.769,3.505,6.09878,,,,,48.762,,,,AAO,-1.22533,0.0758425,0.000937818,1.01765 gb1_T243C,gb1_243,gb1,gb1,P06654,1.01766,NO,243,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.415,-4.367,2.952,,,,,,,1.083,,37.28,PPP,-1.43233,0.177985,0.00308687,1.01766 kka2_1:2_R177M,kka2_1:2_177,Kka2,kka2_1:2,P00552,1.01766,NO,177,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.282,-3.296,1.014,,0.521,T,A,1.2,0.16,1.842,,63.64,HBH,-2.36967,0.295029,0.00768224,1.01766 beta-lactamase_156_D212H,beta-lactamase_156_212,TEM-1,beta-lactamase_156,P62593,1.01768,NO,212,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.624,-4.56,2.936,,0.037,,b,0.75,-0.58,20.222,20.222,74.48,HAB,-1.77667,0.111618,0.00644302,1.01768 beta-lactamase_156_R118I,beta-lactamase_156_118,TEM-1,beta-lactamase_156,P62593,1.01768,NO,118,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.413,-3.968,1.555,,0.457,H,A,1.2,1.39,2.231,,77.62,HBA,-1.785,0.111618,0.00538794,1.01768 beta-lactamase_39_V259T,beta-lactamase_39_259,TEM-1,beta-lactamase_39,P62593,1.01768,NO,259,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.522,,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.0495842,0.0070773,1.01768 beta-lactamase_156_H110T,beta-lactamase_156_110,TEM-1,beta-lactamase_156,P62593,1.01769,NO,110,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-1.706,-3.697,1.991,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.111618,0.00441499,1.01769 beta-lactamase_156_K32Q,beta-lactamase_156_32,TEM-1,beta-lactamase_156,P62593,1.01769,NO,32,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.984,-2.601,0.617,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.111618,0.00401283,1.01769 beta-lactamase_0_A148K,beta-lactamase_0_148,TEM-1,beta-lactamase_0,P62593,1.0177,NO,148,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.757,-2.857,1.1,,0.379,H,A,0.46,-0.55,19.42,19.42,72.73,PHH,-1.40167,0.0500837,0.00547053,1.0177 beta-lactamase_625_I140F,beta-lactamase_625_140,TEM-1,beta-lactamase_625,P62593,1.0177,NO,140,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.733,-2.91,1.177,,0.128,H,A,0.48,0.41,1.628,,73.08,PHO,-1.48733,0.213352,0.00597777,1.0177 beta-lactamase_625_Q97D,beta-lactamase_625_97,TEM-1,beta-lactamase_625,P62593,1.0177,NO,97,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.072,-3.567,1.495,,0.823,G,A,0.64,2.42,16.954,16.954,77.62,PPP,-2.43833,0.213352,0.0045116,1.0177 beta-lactamase_39_A235L,beta-lactamase_39_235,TEM-1,beta-lactamase_39,P62593,1.01771,NO,235,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.266,-3.325,2.059,,0.32,E,B,0.46,-0.86,1.344,,50,OHO,-0.89,0.0495842,0.00493474,1.01771 beta-lactamase_39_A132S,beta-lactamase_39_132,TEM-1,beta-lactamase_39,P62593,1.01772,NO,132,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.9,-2.411,1.511,,,H,A,0.46,-0.93,8.408,,64.69,PHH,-1.138,0.0495842,0.000962524,1.01772 beta-lactamase_625_A34Q,beta-lactamase_625_34,TEM-1,beta-lactamase_625,P62593,1.01772,NO,34,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.059,-4.16,2.101,,,H,A,0.46,-0.54,3.614,,73.78,AHA,-1.74967,0.213352,0.00407913,1.01772 beta-lactamase_625_S221N,beta-lactamase_625_221,TEM-1,beta-lactamase_625,P62593,1.01772,NO,221,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.754,-3.696,1.942,,0.624,H,A,0.27,-0.2,1.495,,74.48,BPH,-1.59967,0.213352,0.0046094,1.01772 beta-lactamase_R118R,beta-lactamase_118,TEM-1,beta-lactamase,P62593,1.01772,NO,118,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.413,-2.413,,5.8227,0.457,H,A,0.68,1.39,2.144,,77.62,HBA,-1.785,0.221079,0.00538794,1.01772 beta-lactamase_39_G194S,beta-lactamase_39_194,TEM-1,beta-lactamase_39,P62593,1.01773,NO,194,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.396,-2.171,0.775,,0.276,S,b,0.29,0.36,4.852,,67.83,POA,-1.832,0.0495842,0.00392163,1.01773 beta-lactamase_39_G240M,beta-lactamase_39_240,TEM-1,beta-lactamase_39,P62593,1.01776,NO,240,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.0495842,0.00591201,1.01776 PSD95pdz3_G345A,PSD95pdz3_345,PSD95pdz3,PSD95pdz3,P31016,1.01776,NO,345,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.008,-2.534,1.526,4.32868,,,,,13.165,,,,OOO,-1.084,0.0758425,0.000771806,1.01776 PSD95pdz3_L349C,PSD95pdz3_349,PSD95pdz3,PSD95pdz3,P31016,1.01776,NO,349,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.347,-4.319,2.972,5.14696,,,,,24.6438,,,,AHP,-1.37667,0.0758425,0.00071841,1.01776 beta-lactamase_156_R220S,beta-lactamase_156_220,TEM-1,beta-lactamase_156,P62593,1.01778,NO,220,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-0.942,-3.349,2.407,,0.295,I,A,1.2,-0.76,2.164,,74.48,HBP,-1.33633,0.111618,0.00232421,1.01778 kka2_1:8_T51A,kka2_1:8_51,Kka2,kka2_1:8,P00552,1.01778,NO,51,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.199,-2.346,0.147,,0.05,E,B,0.82,-0.05,5.399,,63.64,BPA,-1.76767,0.100394,0.00628861,1.01778 kka2_1:8_T51A,kka2_1:8_51,Kka2,kka2_1:8,P00552,1.01778,NO,51,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.199,-2.346,0.147,,0.05,E,B,0.82,-0.05,5.399,,63.64,BPA,-1.76767,0.100394,0.00628861,1.01778 beta-lactamase_625_R41Y,beta-lactamase_625_41,TEM-1,beta-lactamase_625,P62593,1.01779,NO,41,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-0.942,-4.188,3.246,,0.321,E,B,1.2,-0.07,1.186,,65.03,HBH,-1.30267,0.213352,0.00123327,1.01779 beta-lactamase_A200S,beta-lactamase_200,TEM-1,beta-lactamase,P62593,1.01779,NO,200,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.878,-2.183,0.305,5.19406,0.757,H,A,0.47,-0.19,0.436,,77.62,HHP,-2.001,0.221079,0.0060056,1.01779 beta-lactamase_156_A235C,beta-lactamase_156_235,TEM-1,beta-lactamase_156,P62593,1.0178,NO,235,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.266,-4.693,3.427,,0.32,E,B,0.46,-0.86,1.344,,50,OHO,-0.89,0.111618,0.00493474,1.0178 beta-lactamase_156_E46I,beta-lactamase_156_46,TEM-1,beta-lactamase_156,P62593,1.0178,NO,46,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.94,-2.064,0.124,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.111618,0.00427568,1.0178 hsp90_Q582I,hsp90_582,hsp90,hsp90,P02829,1.0178,NO,582,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-3.278,-2.939,0,4.91603,0.453,S,B,,0.67,,,,OPH,-3.249,0.368192,0.000222939,1.0178 beta-lactamase_39_N173W,beta-lactamase_39_173,TEM-1,beta-lactamase_39,P62593,1.01781,NO,173,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-2.663,-5.303,2.64,,1.044,T,l,0.61,1.25,1.426,,77.62,OPA,-1.46633,0.0495842,0.0033769,1.01781 beta-lactamase_156_A77D,beta-lactamase_156_77,TEM-1,beta-lactamase_156,P62593,1.01782,NO,77,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.234,-3.775,2.541,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.111618,0.00282362,1.01782 beta-lactamase_156_M270A,beta-lactamase_156_270,TEM-1,beta-lactamase_156,P62593,1.01782,NO,270,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.111618,0.00767762,1.01782 WW_domain_S184A,WW_domain_184,Yap65,WW_domain,P46937,1.01782,NO,184,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.363,-2.527,1.164,5.06696,,,,,,,,,PPO,-1.39133,0.153962,0.00231095,1.01782 beta-lactamase_625_T186C,beta-lactamase_625_186,TEM-1,beta-lactamase_625,P62593,1.01783,NO,186,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.522,-5.021,2.499,,0.396,H,A,0.22,-0.28,0.515,,77.62,HPP,-1.77633,0.213352,0.00485034,1.01783 beta-lactamase_625_A183W,beta-lactamase_625_183,TEM-1,beta-lactamase_625,P62593,1.01784,NO,183,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.231,-5.466,4.235,,0.155,H,A,0.46,-0.91,23.859,23.859,77.62,HHH,-1.53367,0.213352,0.00296631,1.01784 beta-lactamase_156_R118V,beta-lactamase_156_118,TEM-1,beta-lactamase_156,P62593,1.01785,NO,118,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.413,-3.595,1.182,,0.457,H,A,1.2,1.39,2.231,,77.62,HBA,-1.785,0.111618,0.00538794,1.01785 beta-lactamase_625_Q88G,beta-lactamase_625_88,TEM-1,beta-lactamase_625,P62593,1.01785,NO,88,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.086,-3.448,1.362,,0.807,,B,0.64,2.03,1.84,,77.62,APH,-1.53433,0.213352,0.00504167,1.01785 beta-lactamase_156_R91K,beta-lactamase_156_91,TEM-1,beta-lactamase_156,P62593,1.01786,NO,91,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.392,-2.505,1.113,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.111618,0.00380226,1.01786 beta-lactamase_0_S283R,beta-lactamase_0_283,TEM-1,beta-lactamase_0,P62593,1.01787,NO,283,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.0500837,0.0429138,1.01787 beta-lactamase_156_F228V,beta-lactamase_156_228,TEM-1,beta-lactamase_156,P62593,1.01788,NO,228,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-2.342,-2.889,0.547,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.111618,0.0046669,1.01788 beta-lactamase_625_E238Q,beta-lactamase_625_238,TEM-1,beta-lactamase_625,P62593,1.01788,NO,238,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.213352,0.00743256,1.01788 beta-lactamase_0_A222M,beta-lactamase_0_222,TEM-1,beta-lactamase_0,P62593,1.01789,NO,222,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.103,-4.656,2.553,,0.233,H,A,0.46,-0.25,2.015,,77.62,PHH,-1.63733,0.0500837,0.00466094,1.01789 beta-lactamase_156_A215P,beta-lactamase_156_215,TEM-1,beta-lactamase_156,P62593,1.0179,NO,215,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.503,-3.85,2.347,,,,a,0.46,-0.93,3.583,,74.48,HHO,-1.42633,0.111618,0.00544007,1.0179 beta-lactamase_156_R220F,beta-lactamase_156_220,TEM-1,beta-lactamase_156,P62593,1.0179,NO,220,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-0.942,-4.29,3.348,,0.295,I,A,1.2,-0.76,2.164,,74.48,HBP,-1.33633,0.111618,0.00232421,1.0179 beta-lactamase_39_T69P,beta-lactamase_39_69,TEM-1,beta-lactamase_39,P62593,1.01791,NO,69,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-0.973,-3.715,2.742,,,G,A,0.22,-1.24,4.194,,93.01,PPH,-1.01833,0.0495842,0.00127498,1.01791 beta-lactamase_625_L28Y,beta-lactamase_625_28,TEM-1,beta-lactamase_625,P62593,1.01791,NO,28,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.579,-4.094,2.515,,0.277,H,A,0.55,-0.16,2.716,,93.01,PHH,-2.11333,0.213352,0.00359321,1.01791 beta-lactamase_39_P181A,beta-lactamase_39_181,TEM-1,beta-lactamase_39,P62593,1.01792,NO,181,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.813,-2.357,1.544,,,H,A,0.52,-1.14,1.946,,61.54,HOH,-1.795,0.0495842,0.000703122,1.01792 beta-lactamase_625_N152D,beta-lactamase_625_152,TEM-1,beta-lactamase_625,P62593,1.01792,NO,152,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-2.757,-3.573,0.816,,0.863,H,A,0.61,0.92,2.061,,77.62,BPH,-2.97,0.213352,0.00471429,1.01792 beta-lactamase_156_V259I,beta-lactamase_156_259,TEM-1,beta-lactamase_156,P62593,1.01794,NO,259,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.522,-1.739,0.217,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.111618,0.0070773,1.01794 beta-lactamase_39_Q204D,beta-lactamase_39_204,TEM-1,beta-lactamase_39,P62593,1.01795,NO,204,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-1.382,-3.553,2.171,,0.204,H,A,0.64,0.09,0.489,,66.08,PPH,-1.49067,0.0495842,0.00364106,1.01795 beta-lactamase_0_P165T,beta-lactamase_0_165,TEM-1,beta-lactamase_0,P62593,1.01796,NO,165,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.373,-1.281,-0.092,,0.203,T,A,0.52,-0.31,3.242,,73.78,AOA,-1.359,0.0500837,0.00549538,1.01796 beta-lactamase_0_Y44W,beta-lactamase_0_44,TEM-1,beta-lactamase_0,P62593,1.01796,NO,44,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-2.547,-5.1,2.553,,,E,B,0.21,-0.45,1.751,,73.78,OHH,-1.86267,0.0500837,0.00426364,1.01796 Pab1_N132R,Pab1_132,Pab1,Pab1,P04147,1.01796,NO,132,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-1.079,-3.3,2.221,,0.412,S,l,,0.9,,,,BPH,-1.067,0.175299,0.000347671,1.01796 beta-lactamase_156_E210Y,beta-lactamase_156_210,TEM-1,beta-lactamase_156,P62593,1.01799,NO,210,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.319,-4.214,1.895,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.111618,0.00663582,1.01799 beta-lactamase_39_S51M,beta-lactamase_39_51,TEM-1,beta-lactamase_39,P62593,1.01799,NO,51,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.526,-4.705,3.179,,0.496,T,A,0.27,0.26,2.964,,72.73,PPO,-1.88467,0.0495842,0.00504821,1.01799 beta-lactamase_625_I245L,beta-lactamase_625_245,TEM-1,beta-lactamase_625,P62593,1.01799,NO,245,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.213352,0.00391032,1.01799 beta-lactamase_2500_D36M,beta-lactamase_2500_36,TEM-1,beta-lactamase_2500,P62593,1.018,NO,36,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.732,-4.763,2.031,,0.555,H,A,0.75,1.17,2.26,,77.62,AAP,-1.91167,0.361275,0.00476483,1.018 beta-lactamase_39_E279G,beta-lactamase_39_279,TEM-1,beta-lactamase_39,P62593,1.01801,NO,279,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.038,-3.588,2.55,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.0495842,0.0192826,1.01801 beta-lactamase_39_T186F,beta-lactamase_39_186,TEM-1,beta-lactamase_39,P62593,1.01803,NO,186,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.522,-4.342,1.82,,0.396,H,A,0.22,-0.28,0.515,,77.62,HPP,-1.77633,0.0495842,0.00485034,1.01803 beta-lactamase_39_H151M,beta-lactamase_39_151,TEM-1,beta-lactamase_39,P62593,1.01804,NO,151,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-2.96,-4.581,1.621,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.0495842,0.00216946,1.01804 kka2_1:4_E161G,kka2_1:4_161,Kka2,kka2_1:4,P00552,1.01804,NO,161,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.581,-3.389,1.808,,0.829,G,A,1.52,2.24,1.612,,92.05,AAB,-1.861,0.168804,0.00760103,1.01804 beta-lactamase_39_F58T,beta-lactamase_39_58,TEM-1,beta-lactamase_39,P62593,1.01806,NO,58,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-2.914,-2.91,-0.004,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.0495842,0.00523369,1.01806 PSD95pdz3_A370I,PSD95pdz3_370,PSD95pdz3,PSD95pdz3,P31016,1.01806,NO,370,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.307,-3.242,1.935,5.22304,,,,,17.284,,,,PHP,-1.57967,0.0758425,0.000429106,1.01806 beta-lactamase_39_P165M,beta-lactamase_39_165,TEM-1,beta-lactamase_39,P62593,1.01807,NO,165,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.373,-4.649,3.276,,0.203,T,A,0.52,-0.31,3.907,,73.78,AOA,-1.359,0.0495842,0.00549538,1.01807 beta-lactamase_39_A282G,beta-lactamase_39_282,TEM-1,beta-lactamase_39,P62593,1.01809,NO,282,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.0495842,0.0449821,1.01809 beta-lactamase_0_I258E,beta-lactamase_0_258,TEM-1,beta-lactamase_0,P62593,1.0181,NO,258,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.0500837,0.007931,1.0181 beta-lactamase_39_T27S,beta-lactamase_39_27,TEM-1,beta-lactamase_39,P62593,1.0181,NO,27,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.905,-2.606,0.701,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.0495842,0.00306559,1.0181 PSD95pdz3_R312T,PSD95pdz3_312,PSD95pdz3,PSD95pdz3,P31016,1.0181,NO,312,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.582,-3.103,1.521,5.76826,,,,,12.2409,,,,OBB,-1.46667,0.0758425,0.00196255,1.0181 beta-lactamase_2500_T112K,beta-lactamase_2500_112,TEM-1,beta-lactamase_2500,P62593,1.01811,NO,112,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.186,-2.704,0.518,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.361275,0.00531334,1.01811 beta-lactamase_39_M67G,beta-lactamase_39_67,TEM-1,beta-lactamase_39,P62593,1.01811,NO,67,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-2.231,-2.754,0.523,,0.006,G,P,0.55,-0.81,1.463,,65.03,HHP,-1.502,0.0495842,0.00409753,1.01811 beta-lactamase_625_D36K,beta-lactamase_625_36,TEM-1,beta-lactamase_625,P62593,1.01811,NO,36,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.732,-2.543,-0.189,,0.555,H,A,0.75,1.17,2.26,,77.62,AAP,-1.91167,0.213352,0.00476483,1.01811 beta-lactamase_0_K32T,beta-lactamase_0_32,TEM-1,beta-lactamase_0,P62593,1.01812,NO,32,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.984,-2.479,0.495,,0.563,H,A,2.34,0.34,0.418,,73.08,HBA,-2.04233,0.0500837,0.00401283,1.01812 beta-lactamase_156_D83E,beta-lactamase_156_83,TEM-1,beta-lactamase_156,P62593,1.01812,NO,83,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.066,-2.025,0.959,,0.354,H,A,0.75,0.22,1.281,,48.95,HAH,-1.34733,0.111618,0.00205968,1.01812 beta-lactamase_156_F228L,beta-lactamase_156_228,TEM-1,beta-lactamase_156,P62593,1.01812,NO,228,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-2.342,-3.312,0.97,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.111618,0.0046669,1.01812 beta-lactamase_625_R273Q,beta-lactamase_625_273,TEM-1,beta-lactamase_625,P62593,1.01812,NO,273,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.314,-2.364,0.05,,0.564,H,A,1.2,1.57,1.455,,73.78,ABP,-1.841,0.213352,0.0077952,1.01812 kka2_1:2_E111H,kka2_1:2_111,Kka2,kka2_1:2,P00552,1.01812,NO,111,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.28,-3.298,1.018,,0.155,H,A,1.52,-1.14,2.792,,65.53,HAB,-2.27833,0.295029,0.00746789,1.01812 Pab1_L186I,Pab1_186,Pab1,Pab1,P04147,1.01812,NO,186,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.783,-1.755,-0.028,,,,,,,,,,HHP,-1.56967,0.175299,0.00154968,1.01812 beta-lactamase_39_L28H,beta-lactamase_39_28,TEM-1,beta-lactamase_39,P62593,1.01813,NO,28,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.579,-4.838,3.259,,0.277,H,A,0.55,-0.16,3.262,,93.01,PHH,-2.11333,0.0495842,0.00359321,1.01813 beta-lactamase_39_L205I,beta-lactamase_39_205,TEM-1,beta-lactamase_39,P62593,1.01814,NO,205,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.922,-2.97,2.048,,,H,A,0.55,-0.46,0.846,,42.31,PHH,-1.57767,0.0495842,0.00255802,1.01814 beta-lactamase_625_E119D,beta-lactamase_625_119,TEM-1,beta-lactamase_625,P62593,1.01814,NO,119,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.412,-2.093,0.681,,0.358,H,A,1.04,0.51,1.034,,63.99,BAH,-1.623,0.213352,0.00386966,1.01814 PSD95pdz3_N369K,PSD95pdz3_369,PSD95pdz3,PSD95pdz3,P31016,1.01815,NO,369,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-1.572,-3.009,1.437,5.91569,,,,,24.1262,0.44,,87.71,BPH,-1.487,0.0758425,0.000608412,1.01815 beta-lactamase_2500_I258V,beta-lactamase_2500_258,TEM-1,beta-lactamase_2500,P62593,1.01816,NO,258,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.975,-2.547,0.572,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.361275,0.007931,1.01816 beta-lactamase_625_E46N,beta-lactamase_625_46,TEM-1,beta-lactamase_625,P62593,1.01816,NO,46,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.94,-4.011,2.071,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.213352,0.00427568,1.01816 beta-lactamase_A16L,beta-lactamase_16,TEM-1,beta-lactamase,P62593,1.01816,NO,16,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,,-2.616,0.681,,,,,,,,,,HHH,,0.221079,0.00245392,1.01816 beta-lactamase_A225K,beta-lactamase_225,TEM-1,beta-lactamase,P62593,1.01816,NO,225,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.845,-2.558,0.713,6.5181,1,T,B,0.58,-0.38,4.077,,74.48,OHO,-1.39967,0.221079,0.00465057,1.01816 beta-lactamase_D33C,beta-lactamase_33,TEM-1,beta-lactamase,P62593,1.01816,NO,33,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.321,-5.054,2.733,5.05203,0.366,H,A,0.23,0.33,2.032,,77.62,BAH,-2.12133,0.221079,0.00435556,1.01816 beta-lactamase_D36F,beta-lactamase_36,TEM-1,beta-lactamase,P62593,1.01816,NO,36,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.732,-4.318,1.586,5.39764,0.555,H,A,0.11,1.17,13.689,13.689,77.62,AAP,-1.91167,0.221079,0.00476483,1.01816 beta-lactamase_E102P,beta-lactamase_102,TEM-1,beta-lactamase,P62593,1.01816,NO,102,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.118,-3.88,1.762,6.36157,0.722,S,B,1.5,1.82,1.336,,73.08,HAH,-1.581,0.221079,0.00486633,1.01816 beta-lactamase_E119Q,beta-lactamase_119,TEM-1,beta-lactamase,P62593,1.01816,NO,119,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.412,-2.449,1.037,5.33349,0.358,H,A,1.52,0.51,1.983,,63.99,BAH,-1.623,0.221079,0.00386966,1.01816 beta-lactamase_E195N,beta-lactamase_195,TEM-1,beta-lactamase,P62593,1.01816,NO,195,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.186,-2.977,0.791,7.28489,1.016,S,A,1.52,0.85,2.583,,77.62,OAH,-2.02,0.221079,0.00496565,1.01816 beta-lactamase_E46S,beta-lactamase_46,TEM-1,beta-lactamase,P62593,1.01816,NO,46,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.94,-3.545,1.605,5.36461,0.021,E,B,1.51,0.14,0.373,,59.44,HAH,-2.079,0.221079,0.00427568,1.01816 beta-lactamase_G114G,beta-lactamase_114,TEM-1,beta-lactamase,P62593,1.01816,NO,114,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.094,-1.094,,4.92659,0.011,,p,0.77,0.35,2.148,,41.61,AOH,-1.43733,0.221079,0.00224919,1.01816 beta-lactamase_G226G,beta-lactamase_226,TEM-1,beta-lactamase,P62593,1.01816,NO,226,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.461,-1.461,,5.70682,0.701,T,l,0.77,-0.25,3.199,,74.48,HOH,-1.42933,0.221079,0.00665294,1.01816 beta-lactamase_G251H,beta-lactamase_251,TEM-1,beta-lactamase,P62593,1.01816,NO,251,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.907,-3.385,1.478,5.33865,0.506,T,l,0.73,0.17,10.663,,65.38,AOB,-2.06067,0.221079,0.00733416,1.01816 beta-lactamase_H156G,beta-lactamase_156,TEM-1,beta-lactamase,P62593,1.01816,NO,156,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-3.156,-2.688,-0.468,6.00284,0.753,S,A,0.72,-0.6,6.456,6.456,77.62,ABH,-1.932,0.221079,0.00468596,1.01816 beta-lactamase_K109K,beta-lactamase_109,TEM-1,beta-lactamase,P62593,1.01816,NO,109,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.734,-1.734,,6.05842,0.787,G,A,1.82,2.21,21.623,21.623,72.73,ABB,-1.63333,0.221079,0.00462493,1.01816 beta-lactamase_K109M,beta-lactamase_109,TEM-1,beta-lactamase,P62593,1.01816,NO,109,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.734,-4.742,3.008,6.05842,0.787,G,A,1.82,2.21,21.623,21.623,72.73,ABB,-1.63333,0.221079,0.00462493,1.01816 beta-lactamase_K144D,beta-lactamase_144,TEM-1,beta-lactamase,P62593,1.01816,NO,144,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-2.388,-3.584,1.196,6.02507,0.863,H,A,2.81,1.27,0.515,,77.62,OBA,-1.904,0.221079,0.00481141,1.01816 beta-lactamase_L199N,beta-lactamase_199,TEM-1,beta-lactamase,P62593,1.01816,NO,199,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-2.942,-3.124,0.182,5.57712,0.832,H,A,0.82,0.42,15.302,15.302,77.62,PHH,-2.32933,0.221079,0.0048649,1.01816 beta-lactamase_L47I,beta-lactamase_47,TEM-1,beta-lactamase,P62593,1.01816,NO,47,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.876,-2.384,0.508,5.27297,0.007,E,B,1.07,0.2,1.244,,67.83,AHA,-1.639,0.221079,0.00439844,1.01816 beta-lactamase_N98R,beta-lactamase_98,TEM-1,beta-lactamase,P62593,1.01816,NO,98,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-2.973,-2.618,-0.355,6.59973,0.963,G,A,1.07,1.35,1.332,,77.62,PPA,-2.07867,0.221079,0.00505389,1.01816 beta-lactamase_P165P,beta-lactamase_165,TEM-1,beta-lactamase,P62593,1.01816,NO,165,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.373,-1.373,,5.33889,0.203,T,A,0.99,-0.31,0.414,,73.78,AOA,-1.359,0.221079,0.00549538,1.01816 beta-lactamase_Q204M,beta-lactamase_204,TEM-1,beta-lactamase,P62593,1.01816,NO,204,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-1.382,-4.445,3.063,5.46394,0.204,H,A,0.12,0.09,1.707,,66.08,PPH,-1.49067,0.221079,0.00364106,1.01816 beta-lactamase_Q265G,beta-lactamase_265,TEM-1,beta-lactamase,P62593,1.01816,NO,265,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.58,-2.659,0.079,6.62674,1.116,,A,0.03,1.17,12.514,12.514,69.58,PPH,-1.978,0.221079,0.00811926,1.01816 beta-lactamase_Q265H,beta-lactamase_265,TEM-1,beta-lactamase,P62593,1.01816,NO,265,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.58,-3.43,0.85,6.62674,1.116,,A,0.03,1.17,12.514,12.514,69.58,PPH,-1.978,0.221079,0.00811926,1.01816 beta-lactamase_Q37D,beta-lactamase_37,TEM-1,beta-lactamase,P62593,1.01816,NO,37,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.134,-2.904,0.77,5.69153,0.613,H,A,0.12,1.98,1.318,,73.08,APH,-2.06967,0.221079,0.00425833,1.01816 beta-lactamase_R202T,beta-lactamase_202,TEM-1,beta-lactamase,P62593,1.01816,NO,202,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.292,-3.438,2.146,5.16273,0.188,H,A,0.68,0.62,1.918,,77.62,PBP,-1.54767,0.221079,0.00321899,1.01816 beta-lactamase_S281Y,beta-lactamase_281,TEM-1,beta-lactamase,P62593,1.01816,NO,281,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.247,-4.219,1.972,4.73591,0.128,H,A,0.25,-0.26,2.144,,77.62,HPH,-1.847,0.221079,0.0406482,1.01816 beta-lactamase_S2I,beta-lactamase_2,TEM-1,beta-lactamase,P62593,1.01816,NO,2,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.942,-2.233,0.291,,,,,,,2.36,,65.38,HPH,-2.02767,0.221079,0.00227352,1.01816 beta-lactamase_T138H,beta-lactamase_138,TEM-1,beta-lactamase,P62593,1.01816,NO,138,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.506,-4.649,2.143,5.52585,0.662,H,A,0.3,-0.03,30.445,30.445,73.78,HPP,-1.81233,0.221079,0.00487868,1.01816 beta-lactamase_V101T,beta-lactamase_101,TEM-1,beta-lactamase,P62593,1.01816,NO,101,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.295,-3.446,2.151,5.49045,0.342,,B,0.96,0,1.675,,73.08,HHA,-1.54367,0.221079,0.00374492,1.01816 beta-lactamase_V106V,beta-lactamase_106,TEM-1,beta-lactamase,P62593,1.01816,NO,106,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.218,-1.218,,5.23115,0.258,T,A,0.96,0.24,1.188,,72.73,OHP,-1.04933,0.221079,0.00304168,1.01816 beta-lactamase_V29Q,beta-lactamase_29,TEM-1,beta-lactamase,P62593,1.01816,NO,29,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-2.856,-2.926,0.07,5.58481,0.733,H,A,0.23,-0.78,1.287,,93.01,HHB,-2.24733,0.221079,0.00318969,1.01816 beta-lactamase_0_F64S,beta-lactamase_0_64,TEM-1,beta-lactamase_0,P62593,1.01817,NO,64,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-0.841,-3.611,2.77,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.0500837,0.000947691,1.01817 beta-lactamase_39_F58E,beta-lactamase_39_58,TEM-1,beta-lactamase_39,P62593,1.01817,NO,58,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-2.914,-3.579,0.665,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.0495842,0.00523369,1.01817 beta-lactamase_625_E46K,beta-lactamase_625_46,TEM-1,beta-lactamase_625,P62593,1.01818,NO,46,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.94,-3.66,1.72,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.213352,0.00427568,1.01818 beta-lactamase_625_E46M,beta-lactamase_625_46,TEM-1,beta-lactamase_625,P62593,1.01818,NO,46,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.94,-4.375,2.435,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.213352,0.00427568,1.01818 WW_domain_I193H,WW_domain_193,Yap65,WW_domain,P46937,1.0182,NO,193,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.993,-2.928,0.935,6.15906,,,,,,1.833,,83.33,BHA,-1.756,0.153962,0.00587613,1.0182 beta-lactamase_0_L219R,beta-lactamase_0_219,TEM-1,beta-lactamase_0,P62593,1.01821,NO,219,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.313,-4.126,2.813,,,I,A,0.55,-0.51,6.513,6.513,74.48,HHB,-1.21533,0.0500837,0.00664345,1.01821 beta-lactamase_156_P165D,beta-lactamase_156_165,TEM-1,beta-lactamase_156,P62593,1.01821,NO,165,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.373,-3.54,2.167,,0.203,T,A,0.52,-0.31,3.907,,73.78,AOA,-1.359,0.111618,0.00549538,1.01821 beta-lactamase_156_G142D,beta-lactamase_156_142,TEM-1,beta-lactamase_156,P62593,1.01824,NO,142,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.707,-3.466,2.759,,0.034,,p,0.29,-0.64,0.325,,64.69,OOO,-0.834,0.111618,0.00060149,1.01824 beta-lactamase_39_I244H,beta-lactamase_39_244,TEM-1,beta-lactamase_39,P62593,1.01824,NO,244,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.555,-4.957,3.402,,,E,B,0.48,-0.84,1.325,,77.62,OHH,-1.385,0.0495842,0.00605379,1.01824 beta-lactamase_625_L196C,beta-lactamase_625_196,TEM-1,beta-lactamase_625,P62593,1.01824,NO,196,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-2.478,-4.975,2.497,,0.518,S,A,0.55,1.35,12.152,12.152,77.62,AHH,-1.839,0.213352,0.00512144,1.01824 beta-lactamase_625_S221A,beta-lactamase_625_221,TEM-1,beta-lactamase_625,P62593,1.01824,NO,221,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.754,-1.332,-0.422,,0.624,H,A,0.27,-0.2,1.495,,74.48,BPH,-1.59967,0.213352,0.0046094,1.01824 beta-lactamase_625_T186E,beta-lactamase_625_186,TEM-1,beta-lactamase_625,P62593,1.01824,NO,186,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.522,-2.494,-0.028,,0.396,H,A,0.22,-0.28,0.515,,77.62,HPP,-1.77633,0.213352,0.00485034,1.01824 gb1_D273E,gb1_273,gb1,gb1,P06654,1.01824,NO,273,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.998,-2.245,0.247,,,,,,,3.514,3.514,37.28,AAH,-1.72767,0.177985,0.00318903,1.01824 gb1_V247G,gb1_247,gb1,gb1,P06654,1.01824,NO,247,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.711,-3.405,1.694,,,,,,,0.805,,44.87,HHA,-1.485,0.177985,0.00435373,1.01824 beta-lactamase_39_I258A,beta-lactamase_39_258,TEM-1,beta-lactamase_39,P62593,1.01825,NO,258,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.0495842,0.007931,1.01825 beta-lactamase_156_A211N,beta-lactamase_156_211,TEM-1,beta-lactamase_156,P62593,1.01827,NO,211,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.896,-2.729,0.833,,0.369,T,A,0.46,-0.69,8.527,8.527,77.62,AHA,-1.94633,0.111618,0.00648183,1.01827 beta-lactamase_39_G114N,beta-lactamase_39_114,TEM-1,beta-lactamase_39,P62593,1.01827,NO,114,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.094,-2.731,1.637,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.0495842,0.00224919,1.01827 beta-lactamase_625_A148L,beta-lactamase_625_148,TEM-1,beta-lactamase_625,P62593,1.01827,NO,148,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.757,-3.596,1.839,,0.379,H,A,0.46,-0.55,1.359,,72.73,PHH,-1.40167,0.213352,0.00547053,1.01827 beta-lactamase_625_T112V,beta-lactamase_625_112,TEM-1,beta-lactamase_625,P62593,1.01827,NO,112,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.186,-2.929,0.743,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.213352,0.00531334,1.01827 beta-lactamase_39_T198L,beta-lactamase_39_198,TEM-1,beta-lactamase_39,P62593,1.01828,NO,198,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.168,-3.433,1.265,,0.489,,B,0.22,-0.13,3.614,,73.78,HPH,-1.98767,0.0495842,0.004311,1.01828 beta-lactamase_625_N274D,beta-lactamase_625_274,TEM-1,beta-lactamase_625,P62593,1.01828,NO,274,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.213352,0.0110418,1.01828 beta-lactamase_625_K109N,beta-lactamase_625_109,TEM-1,beta-lactamase_625,P62593,1.01829,NO,109,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.734,-2.767,1.033,,0.787,G,A,2.34,2.21,7.243,,72.73,ABB,-1.63333,0.213352,0.00462493,1.01829 beta-lactamase_39_L49F,beta-lactamase_39_49,TEM-1,beta-lactamase_39,P62593,1.0183,NO,49,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.897,-3.092,1.195,,0.131,T,A,0.55,0.04,13.838,13.838,64.69,AHP,-1.99233,0.0495842,0.00401477,1.0183 beta-lactamase_625_L284M,beta-lactamase_625_284,TEM-1,beta-lactamase_625,P62593,1.0183,NO,284,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.213352,0.0686156,1.0183 beta-lactamase_156_E35M,beta-lactamase_156_35,TEM-1,beta-lactamase_156,P62593,1.01831,NO,35,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-0.869,-4.754,3.885,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.111618,0.00174441,1.01831 beta-lactamase_156_Q97K,beta-lactamase_156_97,TEM-1,beta-lactamase_156,P62593,1.01831,NO,97,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.072,-2.314,0.242,,0.823,G,A,0.64,2.42,4.457,,77.62,PPP,-2.43833,0.111618,0.0045116,1.01831 beta-lactamase_625_E87Y,beta-lactamase_625_87,TEM-1,beta-lactamase_625,P62593,1.01831,NO,87,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.421,-4.262,2.841,,0.048,,B,1.04,0.92,17.923,17.923,64.69,PAP,-1.969,0.213352,0.00337888,1.01831 beta-lactamase_39_R257M,beta-lactamase_39_257,TEM-1,beta-lactamase_39,P62593,1.01832,NO,257,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.0495842,0.00756629,1.01832 kka2_1:8_L243R,kka2_1:8_243,Kka2,kka2_1:8,P00552,1.01832,NO,243,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-2.651,-2.013,-0.638,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.100394,0.00884927,1.01832 kka2_1:8_L243R,kka2_1:8_243,Kka2,kka2_1:8,P00552,1.01832,NO,243,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-2.651,-2.013,-0.638,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.100394,0.00884927,1.01832 beta-lactamase_39_A132G,beta-lactamase_39_132,TEM-1,beta-lactamase_39,P62593,1.01833,NO,132,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.9,-3.009,2.109,,,H,A,0.46,-0.93,8.408,,64.69,PHH,-1.138,0.0495842,0.000962524,1.01833 PSD95pdz3_G383K,PSD95pdz3_383,PSD95pdz3,PSD95pdz3,P31016,1.01833,NO,383,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.008,-3.364,2.356,5.17213,,,,,20.5325,,,,HOP,-1.338,0.0758425,0.000233044,1.01833 beta-lactamase_156_M67A,beta-lactamase_156_67,TEM-1,beta-lactamase_156,P62593,1.01834,NO,67,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-2.231,-2.183,-0.048,,0.006,G,P,0.55,-0.81,1.463,,65.03,HHP,-1.502,0.111618,0.00409753,1.01834 beta-lactamase_39_T131S,beta-lactamase_39_131,TEM-1,beta-lactamase_39,P62593,1.01834,NO,131,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.328,-1.912,0.584,,,H,A,0.22,-0.69,3.306,,67.48,PPH,-1.00867,0.0495842,0.00345886,1.01834 beta-lactamase_156_A170V,beta-lactamase_156_170,TEM-1,beta-lactamase_156,P62593,1.01836,NO,170,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.237,-2.64,1.403,,0.126,,L,0.46,-0.35,3.7,,64.69,AHH,-1.63267,0.111618,0.00431903,1.01836 beta-lactamase_39_S256N,beta-lactamase_39_256,TEM-1,beta-lactamase_39,P62593,1.01836,NO,256,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.0495842,0.00710634,1.01836 beta-lactamase_39_A124S,beta-lactamase_39_124,TEM-1,beta-lactamase_39,P62593,1.01837,NO,124,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.181,-3.066,1.885,,,H,A,0.46,-0.9,1.367,,64.34,HHH,-1.152,0.0495842,0.00481399,1.01837 PSD95pdz3_G333W,PSD95pdz3_333,PSD95pdz3,PSD95pdz3,P31016,1.01837,NO,333,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.008,-4.779,3.771,5.09445,,,,,48.755,,,,AOA,-1.22533,0.0758425,0.00092544,1.01837 gb1_K239N,gb1_239,gb1,gb1,P06654,1.01838,NO,239,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-3.043,-1.65,-1.393,,,,,,,1.326,,45.54,HBO,-2.31467,0.177985,0.00207004,1.01838 beta-lactamase_0_I206E,beta-lactamase_0_206,TEM-1,beta-lactamase_0,P62593,1.01839,NO,206,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-2.429,-2.747,0.318,,0.173,H,A,0.48,-0.34,3.411,,77.62,HHA,-1.805,0.0500837,0.00528934,1.01839 beta-lactamase_0_Q203Y,beta-lactamase_0_203,TEM-1,beta-lactamase_0,P62593,1.0184,NO,203,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.168,-4.35,2.182,,0.47,H,A,0.64,-0.38,14.541,14.541,65.38,BPP,-1.614,0.0500837,0.00631514,1.0184 beta-lactamase_2500_T186E,beta-lactamase_2500_186,TEM-1,beta-lactamase_2500,P62593,1.0184,NO,186,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.522,-2.494,-0.028,,0.396,H,A,0.22,-0.28,2.144,,77.62,HPP,-1.77633,0.361275,0.00485034,1.0184 beta-lactamase_39_E195A,beta-lactamase_39_195,TEM-1,beta-lactamase_39,P62593,1.0184,NO,195,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.186,-2.778,0.592,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.0495842,0.00496565,1.0184 beta-lactamase_39_I280V,beta-lactamase_39_280,TEM-1,beta-lactamase_39,P62593,1.0184,NO,280,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.0495842,0.0530888,1.0184 beta-lactamase_0_A200S,beta-lactamase_0_200,TEM-1,beta-lactamase_0,P62593,1.01841,NO,200,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.878,-2.183,0.305,,0.757,H,A,0.46,-0.19,16.368,16.368,77.62,HHP,-2.001,0.0500837,0.0060056,1.01841 beta-lactamase_156_A215G,beta-lactamase_156_215,TEM-1,beta-lactamase_156,P62593,1.01842,NO,215,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.503,-1.579,0.076,,,,a,0.46,-0.93,3.583,,74.48,HHO,-1.42633,0.111618,0.00544007,1.01842 beta-lactamase_156_M270W,beta-lactamase_156_270,TEM-1,beta-lactamase_156,P62593,1.01842,NO,270,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.111618,0.00767762,1.01842 beta-lactamase_E175V,beta-lactamase_175,TEM-1,beta-lactamase,P62593,1.01842,NO,175,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.336,-2.38,0.044,6.0311,0.551,,A,0.75,1.05,5.316,,77.62,AAB,-1.31233,0.221079,0.00482205,1.01842 beta-lactamase_156_K53N,beta-lactamase_156_53,TEM-1,beta-lactamase_156,P62593,1.01844,NO,53,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-2.313,-3.809,1.496,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.111618,0.00383383,1.01844 beta-lactamase_39_R118Q,beta-lactamase_39_118,TEM-1,beta-lactamase_39,P62593,1.01845,NO,118,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.413,-3.932,1.519,,0.457,H,A,1.2,1.39,3.961,,77.62,HBA,-1.785,0.0495842,0.00538794,1.01845 beta-lactamase_625_S256M,beta-lactamase_625_256,TEM-1,beta-lactamase_625,P62593,1.01845,NO,256,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.213352,0.00710634,1.01845 beta-lactamase_E175P,beta-lactamase_175,TEM-1,beta-lactamase,P62593,1.01845,NO,175,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.336,-1.972,-0.364,6.0311,0.551,,A,0.75,1.05,5.316,,77.62,AAB,-1.31233,0.221079,0.00482205,1.01845 beta-lactamase_156_G154M,beta-lactamase_156_154,TEM-1,beta-lactamase_156,P62593,1.01846,NO,154,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.823,-4.936,4.113,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.111618,0.00180205,1.01846 beta-lactamase_156_P181I,beta-lactamase_156_181,TEM-1,beta-lactamase_156,P62593,1.01846,NO,181,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.813,-3.974,3.161,,,H,A,0.52,-1.14,1.078,,61.54,HOH,-1.795,0.111618,0.000703122,1.01846 beta-lactamase_39_R202N,beta-lactamase_39_202,TEM-1,beta-lactamase_39,P62593,1.01846,NO,202,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.292,-3.543,2.251,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.0495842,0.00321899,1.01846 beta-lactamase_39_V157S,beta-lactamase_39_157,TEM-1,beta-lactamase_39,P62593,1.01846,NO,157,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.751,-2.878,1.127,,0.308,S,a,0.44,-0.75,10.364,10.364,69.58,BHP,-2.00767,0.0495842,0.00506849,1.01846 beta-lactamase_625_L219I,beta-lactamase_625_219,TEM-1,beta-lactamase_625,P62593,1.01846,NO,219,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.313,-1.692,0.379,,,I,A,0.55,-0.51,5.627,,74.48,HHB,-1.21533,0.213352,0.00664345,1.01846 kka2_1:8_V153L,kka2_1:8_153,Kka2,kka2_1:8,P00552,1.01846,NO,153,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.092,-2.743,1.651,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.100394,0.00501119,1.01846 kka2_1:8_V153L,kka2_1:8_153,Kka2,kka2_1:8,P00552,1.01846,NO,153,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.092,-2.743,1.651,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.100394,0.00501119,1.01846 beta-lactamase_156_D271W,beta-lactamase_156_271,TEM-1,beta-lactamase_156,P62593,1.01847,NO,271,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.111618,0.00752082,1.01847 beta-lactamase_39_P60Q,beta-lactamase_39_60,TEM-1,beta-lactamase_39,P62593,1.01848,NO,60,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-2.469,-3.986,1.517,,0.256,T,A,0.52,-0.56,21.37,21.37,77.62,BOA,-1.97633,0.0495842,0.00521318,1.01848 beta-lactamase_39_R273A,beta-lactamase_39_273,TEM-1,beta-lactamase_39,P62593,1.01848,NO,273,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.314,-1.856,-0.458,,0.564,H,A,1.2,1.57,2.163,,73.78,ABP,-1.841,0.0495842,0.0077952,1.01848 beta-lactamase_E237A,beta-lactamase_237,TEM-1,beta-lactamase,P62593,1.01848,NO,237,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.058,-2.128,0.07,5.42877,0.583,S,B,1.62,1.2,2.144,,77.62,OAB,-1.61467,0.221079,0.0048626,1.01848 beta-lactamase_156_A200K,beta-lactamase_156_200,TEM-1,beta-lactamase_156,P62593,1.0185,NO,200,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.878,-2.669,0.791,,0.757,H,A,0.46,-0.19,16.368,16.368,77.62,HHP,-2.001,0.111618,0.0060056,1.0185 beta-lactamase_K190E,beta-lactamase_190,TEM-1,beta-lactamase,P62593,1.0185,NO,190,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.994,-3.44,1.446,5.49163,0.371,H,A,1.82,0.16,29.753,29.753,77.62,BBH,-1.64167,0.221079,0.00574527,1.0185 kka2_1:8_P98F,kka2_1:8_98,Kka2,kka2_1:8,P00552,1.0185,NO,98,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.526,-4.51,2.984,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.100394,0.00622754,1.0185 kka2_1:8_P98F,kka2_1:8_98,Kka2,kka2_1:8,P00552,1.0185,NO,98,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.526,-4.51,2.984,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.100394,0.00622754,1.0185 beta-lactamase_0_Q204V,beta-lactamase_0_204,TEM-1,beta-lactamase_0,P62593,1.01851,NO,204,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-1.382,-3.595,2.213,,0.204,H,A,0.64,0.09,2.646,,66.08,PPH,-1.49067,0.0500837,0.00364106,1.01851 beta-lactamase_39_A84K,beta-lactamase_39_84,TEM-1,beta-lactamase_39,P62593,1.01851,NO,84,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.651,-2.484,0.833,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.0495842,0.00503822,1.01851 beta-lactamase_0_R59Y,beta-lactamase_0_59,TEM-1,beta-lactamase_0,P62593,1.01852,NO,59,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.345,-4.267,2.922,,0.329,S,L,1.2,-0.09,2.919,,73.08,HBO,-2.24267,0.0500837,0.00318082,1.01852 beta-lactamase_625_N152K,beta-lactamase_625_152,TEM-1,beta-lactamase_625,P62593,1.01852,NO,152,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-2.757,-2.892,0.135,,0.863,H,A,0.61,0.92,2.061,,77.62,BPH,-2.97,0.213352,0.00471429,1.01852 beta-lactamase_39_L111I,beta-lactamase_39_111,TEM-1,beta-lactamase_39,P62593,1.01853,NO,111,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.76,-2.153,0.393,,0.328,T,A,0.55,0.93,4.334,,64.34,BHP,-1.884,0.0495842,0.00480671,1.01853 beta-lactamase_625_A183M,beta-lactamase_625_183,TEM-1,beta-lactamase_625,P62593,1.01854,NO,183,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.231,-4.59,3.359,,0.155,H,A,0.46,-0.91,23.859,23.859,77.62,HHH,-1.53367,0.213352,0.00296631,1.01854 beta-lactamase_39_R242A,beta-lactamase_39_242,TEM-1,beta-lactamase_39,P62593,1.01855,NO,242,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.0495842,0.00452879,1.01855 beta-lactamase_E166S,beta-lactamase_166,TEM-1,beta-lactamase,P62593,1.01855,NO,166,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.756,-2.582,0.826,5.60527,0.508,G,A,0.52,1.05,2.124,,73.08,OAH,-1.42233,0.221079,0.00512989,1.01855 beta-lactamase_156_R63I,beta-lactamase_156_63,TEM-1,beta-lactamase_156,P62593,1.01856,NO,63,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-0.943,-3.824,2.881,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.111618,0.00126938,1.01856 E1_Ubiquitin_F45L,E1_Ubiquitin_45,Uba1,E1_Ubiquitin,P0CG63,1.01857,NO,45,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.149,-2.725,1.576,,0.26,E,B,,-0.99,,,,HHH,-1.316,0.18783,0.00193245,1.01857 E1_Ubiquitin_K48T,E1_Ubiquitin_48,Uba1,E1_Ubiquitin,P0CG63,1.01857,NO,48,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.219,-3.292,2.073,,0.132,E,B,,-0.28,,,,OBO,-1.109,0.18783,0.00100363,1.01857 E1_Ubiquitin_L71I,E1_Ubiquitin_71,Uba1,E1_Ubiquitin,P0CG63,1.01857,NO,71,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.039,-2.702,1.663,,0.591,E,B,,-0.69,,,,BHB,-1.19433,0.18783,0.00148349,1.01857 E1_Ubiquitin_L71V,E1_Ubiquitin_71,Uba1,E1_Ubiquitin,P0CG63,1.01857,NO,71,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.039,-2.671,1.632,,0.591,E,B,,-0.69,,,,BHB,-1.19433,0.18783,0.00148349,1.01857 E1_Ubiquitin_R74S,E1_Ubiquitin_74,Uba1,E1_Ubiquitin,P0CG63,1.01857,NO,74,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.302,-3.196,1.894,,0.838,T,A,,3.15,,,,HBO,-1.11333,0.18783,0.00180798,1.01857 beta-lactamase_2500_L199I,beta-lactamase_2500_199,TEM-1,beta-lactamase_2500,P62593,1.01858,NO,199,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-2.942,-3.16,0.218,,0.832,H,A,0.55,0.42,15.504,15.504,77.62,PHH,-2.32933,0.361275,0.0048649,1.01858 beta-lactamase_625_T112L,beta-lactamase_625_112,TEM-1,beta-lactamase_625,P62593,1.01859,NO,112,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.186,-3.575,1.389,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.213352,0.00531334,1.01859 beta-lactamase_156_E26A,beta-lactamase_156_26,TEM-1,beta-lactamase_156,P62593,1.0186,NO,26,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.454,-2.207,-0.247,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.111618,0.00297948,1.0186 beta-lactamase_39_R92L,beta-lactamase_39_92,TEM-1,beta-lactamase_39,P62593,1.0186,NO,92,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.718,-2.788,1.07,,0.479,E,B,1.2,1.36,0.389,,65.38,BBH,-1.50367,0.0495842,0.00429626,1.0186 beta-lactamase_0_R41T,beta-lactamase_0_41,TEM-1,beta-lactamase_0,P62593,1.01861,NO,41,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-0.942,-3.385,2.443,,0.321,E,B,1.2,-0.07,2.68,,65.03,HBH,-1.30267,0.0500837,0.00123327,1.01861 beta-lactamase_2500_A268M,beta-lactamase_2500_268,TEM-1,beta-lactamase_2500,P62593,1.01862,NO,268,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.023,-2.456,0.433,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.361275,0.0102525,1.01862 beta-lactamase_625_S80Q,beta-lactamase_625_80,TEM-1,beta-lactamase_625,P62593,1.01863,NO,80,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.029,-3.941,1.912,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.213352,0.00565569,1.01863 beta-lactamase_T186I,beta-lactamase_186,TEM-1,beta-lactamase,P62593,1.01865,NO,186,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.522,-3.94,1.418,5.07364,0.396,H,A,0.3,-0.28,2.144,,77.62,HPP,-1.77633,0.221079,0.00485034,1.01865 PSD95pdz3_D348W,PSD95pdz3_348,PSD95pdz3,PSD95pdz3,P31016,1.01866,NO,348,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.264,-5.229,3.965,5.02473,,,,,16.8925,,,,HAH,-1.306,0.0758425,0.000731866,1.01866 beta-lactamase_625_I54Y,beta-lactamase_625_54,TEM-1,beta-lactamase_625,P62593,1.01867,NO,54,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-2.838,-4.264,1.426,,0.669,E,B,0.48,-0.14,3.946,,73.78,BHH,-2.337,0.213352,0.00403589,1.01867 gb1_A246S,gb1_246,gb1,gb1,P06654,1.01867,NO,246,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.175,-2.671,1.496,,,,,,,,,,AHH,-1.87033,0.177985,0.00190625,1.01867 beta-lactamase_0_N50S,beta-lactamase_0_50,TEM-1,beta-lactamase_0,P62593,1.01868,NO,50,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-2.979,-3.331,0.352,,0.912,T,A,0.61,1.24,9.874,9.874,77.62,HPP,-2.134,0.0500837,0.0047211,1.01868 beta-lactamase_39_R275I,beta-lactamase_39_275,TEM-1,beta-lactamase_39,P62593,1.01868,NO,275,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.397,-4.133,2.736,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.0495842,0.0141984,1.01868 kka2_1:8_A56F,kka2_1:8_56,Kka2,kka2_1:8,P00552,1.01868,NO,56,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.083,-4.441,2.358,,0.796,T,A,0.46,1.39,10.511,,71.59,OHH,-1.86867,0.100394,0.00717715,1.01868 kka2_1:8_A56F,kka2_1:8_56,Kka2,kka2_1:8,P00552,1.01868,NO,56,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.083,-4.441,2.358,,0.796,T,A,0.46,1.39,10.511,,71.59,OHH,-1.86867,0.100394,0.00717715,1.01868 beta-lactamase_156_L73S,beta-lactamase_156_73,TEM-1,beta-lactamase_156,P62593,1.01869,NO,73,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.507,-3.664,2.157,,,H,A,0.55,-0.64,2.09,,67.83,HHH,-1.487,0.111618,0.00488983,1.01869 kka2_1:8_F206V,kka2_1:8_206,Kka2,kka2_1:8,P00552,1.01869,NO,206,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.349,-2.691,1.342,,0.006,E,B,1.62,-1.21,1.052,,63.64,OHH,-1.04,0.100394,0.00936868,1.01869 kka2_1:8_F206V,kka2_1:8_206,Kka2,kka2_1:8,P00552,1.01869,NO,206,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.349,-2.691,1.342,,0.006,E,B,1.62,-1.21,1.052,,63.64,OHH,-1.04,0.100394,0.00936868,1.01869 beta-lactamase_39_I206M,beta-lactamase_39_206,TEM-1,beta-lactamase_39,P62593,1.01871,NO,206,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-2.429,-3.069,0.64,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.0495842,0.00528934,1.01871 beta-lactamase_39_V157Q,beta-lactamase_39_157,TEM-1,beta-lactamase_39,P62593,1.01871,NO,157,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.751,-4.045,2.294,,0.308,S,a,0.44,-0.75,10.364,10.364,69.58,BHP,-2.00767,0.0495842,0.00506849,1.01871 kka2_1:1_A168H,kka2_1:1_168,Kka2,kka2_1:1,P00552,1.01871,NO,168,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.989,-3.256,1.267,,0.67,H,A,0.46,0.15,25.546,25.546,64.39,OHA,-2.12933,0.520039,0.00806773,1.01871 beta-lactamase_156_E62Y,beta-lactamase_156_62,TEM-1,beta-lactamase_156,P62593,1.01872,NO,62,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.193,-4.285,3.092,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.111618,0.00264802,1.01872 beta-lactamase_625_E272R,beta-lactamase_625_272,TEM-1,beta-lactamase_625,P62593,1.01872,NO,272,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.213352,0.00545371,1.01872 kka2_1:2_W15R,kka2_1:2_15,Kka2,kka2_1:2,P00552,1.01873,NO,15,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-1.392,-4.195,2.803,,0.01,G,A,0.47,0.15,2.586,,52.27,HHH,-2.10533,0.295029,0.00585505,1.01873 beta-lactamase_0_A247T,beta-lactamase_0_247,TEM-1,beta-lactamase_0,P62593,1.01874,NO,247,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.0500837,0.00611275,1.01874 beta-lactamase_156_A84I,beta-lactamase_156_84,TEM-1,beta-lactamase_156,P62593,1.01874,NO,84,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.651,-3.932,2.281,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.111618,0.00503822,1.01874 beta-lactamase_156_R41M,beta-lactamase_156_41,TEM-1,beta-lactamase_156,P62593,1.01874,NO,41,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-0.942,-4.506,3.564,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.111618,0.00123327,1.01874 beta-lactamase_156_V260I,beta-lactamase_156_260,TEM-1,beta-lactamase_156,P62593,1.01875,NO,260,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.111618,0.00471757,1.01875 PSD95pdz3_G344H,PSD95pdz3_344,PSD95pdz3,PSD95pdz3,P31016,1.01875,NO,344,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.008,-4.362,3.354,4.83855,,,,,14.06,,,,HOO,-1.10767,0.0758425,0.00078498,1.01875 beta-lactamase_156_F149N,beta-lactamase_156_149,TEM-1,beta-lactamase_156,P62593,1.01876,NO,149,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.299,-4.055,2.756,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.111618,0.00418462,1.01876 beta-lactamase_2500_L199F,beta-lactamase_2500_199,TEM-1,beta-lactamase_2500,P62593,1.01876,NO,199,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-2.942,-4.403,1.461,,0.832,H,A,0.55,0.42,15.504,15.504,77.62,PHH,-2.32933,0.361275,0.0048649,1.01876 beta-lactamase_625_R63N,beta-lactamase_625_63,TEM-1,beta-lactamase_625,P62593,1.01876,NO,63,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-0.943,-3.531,2.588,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.213352,0.00126938,1.01876 beta-lactamase_156_A211V,beta-lactamase_156_211,TEM-1,beta-lactamase_156,P62593,1.01877,NO,211,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.896,-3.651,1.755,,0.369,T,A,0.46,-0.69,8.527,8.527,77.62,AHA,-1.94633,0.111618,0.00648183,1.01877 beta-lactamase_39_R220N,beta-lactamase_39_220,TEM-1,beta-lactamase_39,P62593,1.01877,NO,220,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-0.942,-3.516,2.574,,0.295,I,A,1.2,-0.76,1.596,,74.48,HBP,-1.33633,0.0495842,0.00232421,1.01877 PSD95pdz3_E352Y,PSD95pdz3_352,PSD95pdz3,PSD95pdz3,P31016,1.01878,NO,352,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.587,-3.939,2.352,5.49659,,,,,24.2,2.525,,86.88,OAH,-1.314,0.0758425,0.000892231,1.01878 beta-lactamase_625_R275K,beta-lactamase_625_275,TEM-1,beta-lactamase_625,P62593,1.01879,NO,275,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.213352,0.0141984,1.01879 kka2_1:8_V97C,kka2_1:8_97,Kka2,kka2_1:8,P00552,1.01879,NO,97,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.453,-4.797,3.344,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.100394,0.00737869,1.01879 kka2_1:8_V97C,kka2_1:8_97,Kka2,kka2_1:8,P00552,1.01879,NO,97,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.453,-4.797,3.344,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.100394,0.00737869,1.01879 beta-lactamase_2500_T186K,beta-lactamase_2500_186,TEM-1,beta-lactamase_2500,P62593,1.0188,NO,186,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.522,-2.678,0.156,,0.396,H,A,0.22,-0.28,2.144,,77.62,HPP,-1.77633,0.361275,0.00485034,1.0188 gb1_T251L,gb1_251,gb1,gb1,P06654,1.01881,NO,251,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.794,-2.993,1.199,,,,,,,3.514,3.514,37.28,HPH,-1.56067,0.177985,0.00232932,1.01881 kka2_1:2_D33K,kka2_1:2_33,Kka2,kka2_1:2,P00552,1.01881,NO,33,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.186,-3.557,1.371,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.295029,0.00633568,1.01881 WW_domain_P172I,WW_domain_172,Yap65,WW_domain,P46937,1.01881,NO,172,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.035,-3.787,2.752,,,,,,,,,,HOH,-1.233,0.153962,0.000991485,1.01881 beta-lactamase_156_K190A,beta-lactamase_156_190,TEM-1,beta-lactamase_156,P62593,1.01882,NO,190,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.994,-2.146,0.152,,0.371,H,A,2.34,0.16,1.513,,77.62,BBH,-1.64167,0.111618,0.00574527,1.01882 beta-lactamase_39_A34E,beta-lactamase_39_34,TEM-1,beta-lactamase_39,P62593,1.01883,NO,34,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.059,-3.743,1.684,,,H,A,0.46,-0.54,13.292,13.292,73.78,AHA,-1.74967,0.0495842,0.00407913,1.01883 beta-lactamase_39_G194N,beta-lactamase_39_194,TEM-1,beta-lactamase_39,P62593,1.01883,NO,194,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.396,-2.573,1.177,,0.276,S,b,0.29,0.36,4.852,,67.83,POA,-1.832,0.0495842,0.00392163,1.01883 beta-lactamase_Q88H,beta-lactamase_88,TEM-1,beta-lactamase,P62593,1.01883,NO,88,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.086,-4.599,2.513,5.8056,0.807,,B,0.12,2.03,1.84,,77.62,APH,-1.53433,0.221079,0.00504167,1.01883 beta-lactamase_156_M270H,beta-lactamase_156_270,TEM-1,beta-lactamase_156,P62593,1.01884,NO,270,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.111618,0.00767762,1.01884 beta-lactamase_39_E238T,beta-lactamase_39_238,TEM-1,beta-lactamase_39,P62593,1.01884,NO,238,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.0495842,0.00743256,1.01884 kka2_1:1_G234N,kka2_1:1_234,Kka2,kka2_1:1,P00552,1.01886,NO,234,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-2.9,-3.105,0.205,,0.494,H,A,0.29,-0.29,1.753,,71.59,OOA,-1.86767,0.520039,0.00984449,1.01886 kka2_1:8_D156T,kka2_1:8_156,Kka2,kka2_1:8,P00552,1.01886,NO,156,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.696,-1.988,0.292,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.100394,0.00926998,1.01886 kka2_1:8_D156T,kka2_1:8_156,Kka2,kka2_1:8,P00552,1.01886,NO,156,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.696,-1.988,0.292,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.100394,0.00926998,1.01886 beta-lactamase_156_V157W,beta-lactamase_156_157,TEM-1,beta-lactamase_156,P62593,1.01887,NO,157,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.751,-5.264,3.513,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.111618,0.00506849,1.01887 beta-lactamase_39_T138A,beta-lactamase_39_138,TEM-1,beta-lactamase_39,P62593,1.01887,NO,138,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.506,-2.248,-0.258,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.0495842,0.00487868,1.01887 beta-lactamase_625_K109T,beta-lactamase_625_109,TEM-1,beta-lactamase_625,P62593,1.01887,NO,109,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.734,-2.559,0.825,,0.787,G,A,2.34,2.21,7.243,,72.73,ABB,-1.63333,0.213352,0.00462493,1.01887 beta-lactamase_D250N,beta-lactamase_250,TEM-1,beta-lactamase,P62593,1.01887,NO,250,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.335,-2.569,0.234,5.72026,0.89,T,L,0.23,1.53,24.737,24.737,66.08,OAO,-1.85133,0.221079,0.00550899,1.01887 beta-lactamase_156_E108C,beta-lactamase_156_108,TEM-1,beta-lactamase_156,P62593,1.01889,NO,108,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.46,-5.208,3.748,,0.572,G,A,1.04,1.87,8.602,8.602,72.73,PAB,-1.437,0.111618,0.00413372,1.01889 beta-lactamase_0_S57T,beta-lactamase_0_57,TEM-1,beta-lactamase_0,P62593,1.01891,NO,57,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.918,-2.297,0.379,,0.352,E,B,0.27,-0.18,1.454,,72.73,APH,-2.29167,0.0500837,0.00492804,1.01891 beta-lactamase_156_V29H,beta-lactamase_156_29,TEM-1,beta-lactamase_156,P62593,1.01891,NO,29,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-2.856,-4.571,1.715,,0.733,H,A,0.44,-0.78,3.685,,93.01,HHB,-2.24733,0.111618,0.00318969,1.01891 beta-lactamase_39_E61M,beta-lactamase_39_61,TEM-1,beta-lactamase_39,P62593,1.01891,NO,61,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.115,-4.881,2.766,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.0495842,0.00440955,1.01891 beta-lactamase_156_A84M,beta-lactamase_156_84,TEM-1,beta-lactamase_156,P62593,1.01892,NO,84,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.651,-4.707,3.056,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.111618,0.00503822,1.01892 beta-lactamase_K53T,beta-lactamase_53,TEM-1,beta-lactamase,P62593,1.01892,NO,53,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-2.313,-2.702,0.389,5.93654,0.589,,B,1.82,1.15,19.72,19.72,77.62,OBH,-2.1,0.221079,0.00383383,1.01892 beta-lactamase_0_P217R,beta-lactamase_0_217,TEM-1,beta-lactamase_0,P62593,1.01893,NO,217,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-2.062,-3.069,1.007,,0.496,I,A,0.52,-0.33,1.087,,74.48,OOH,-1.64333,0.0500837,0.00463211,1.01893 beta-lactamase_39_R189F,beta-lactamase_39_189,TEM-1,beta-lactamase_39,P62593,1.01894,NO,189,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.844,-4.275,2.431,,0.278,H,A,1.2,1.01,12.11,12.11,72.73,HBB,-1.668,0.0495842,0.0050699,1.01894 beta-lactamase_156_E145M,beta-lactamase_156_145,TEM-1,beta-lactamase_156,P62593,1.01896,NO,145,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.357,-4.807,2.45,,0.545,H,A,1.04,0.79,3.661,,77.62,BAH,-2.069,0.111618,0.00553285,1.01896 beta-lactamase_156_L284G,beta-lactamase_156_284,TEM-1,beta-lactamase_156,P62593,1.01896,NO,284,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.111618,0.0686156,1.01896 beta-lactamase_625_Q88S,beta-lactamase_625_88,TEM-1,beta-lactamase_625,P62593,1.01896,NO,88,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.086,-2.48,0.394,,0.807,,B,0.64,2.03,1.84,,77.62,APH,-1.53433,0.213352,0.00504167,1.01896 kka2_1:4_E161H,kka2_1:4_161,Kka2,kka2_1:4,P00552,1.01897,NO,161,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.581,-4.674,3.093,,0.829,G,A,1.52,2.24,1.612,,92.05,AAB,-1.861,0.168804,0.00760103,1.01897 PSD95pdz3_I377T,PSD95pdz3_377,PSD95pdz3,PSD95pdz3,P31016,1.01897,NO,377,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.873,-3.203,1.33,4.9532,,,,,19.185,2.364,,87.71,HHH,-1.49567,0.0758425,0.000795475,1.01897 beta-lactamase_2500_T186I,beta-lactamase_2500_186,TEM-1,beta-lactamase_2500,P62593,1.01898,NO,186,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.522,-3.94,1.418,,0.396,H,A,0.22,-0.28,2.144,,77.62,HPP,-1.77633,0.361275,0.00485034,1.01898 beta-lactamase_39_S96I,beta-lactamase_39_96,TEM-1,beta-lactamase_39,P62593,1.01899,NO,96,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.27,-3.225,0.955,,0.368,,b,0.27,0.39,2.516,,73.78,HPP,-2.019,0.0495842,0.00551835,1.01899 beta-lactamase_39_T186H,beta-lactamase_39_186,TEM-1,beta-lactamase_39,P62593,1.01899,NO,186,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.522,-4.717,2.195,,0.396,H,A,0.22,-0.28,0.515,,77.62,HPP,-1.77633,0.0495842,0.00485034,1.01899 beta-lactamase_625_I54F,beta-lactamase_625_54,TEM-1,beta-lactamase_625,P62593,1.01899,NO,54,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-2.838,-4.242,1.404,,0.669,E,B,0.48,-0.14,3.946,,73.78,BHH,-2.337,0.213352,0.00403589,1.01899 beta-lactamase_156_Q86Y,beta-lactamase_156_86,TEM-1,beta-lactamase_156,P62593,1.019,NO,86,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.4,-4.372,1.972,,0.696,S,A,0.64,2.38,27.704,27.704,77.62,OPA,-1.61067,0.111618,0.00450027,1.019 beta-lactamase_39_D174L,beta-lactamase_39_174,TEM-1,beta-lactamase_39,P62593,1.019,NO,174,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.738,-3.808,3.07,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.0495842,0.00125633,1.019 beta-lactamase_625_E238C,beta-lactamase_625_238,TEM-1,beta-lactamase_625,P62593,1.019,NO,238,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.213352,0.00743256,1.019 beta-lactamase_156_E119M,beta-lactamase_156_119,TEM-1,beta-lactamase_156,P62593,1.01901,NO,119,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.412,-4.79,3.378,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.111618,0.00386966,1.01901 beta-lactamase_A9T,beta-lactamase_9,TEM-1,beta-lactamase,P62593,1.01901,NO,9,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.147,-2.689,0.542,,,,,,,5.128,,72.73,HHH,-2.04267,0.221079,0.00247263,1.01901 beta-lactamase_156_K190Y,beta-lactamase_156_190,TEM-1,beta-lactamase_156,P62593,1.01902,NO,190,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.994,-4.283,2.289,,0.371,H,A,2.34,0.16,1.513,,77.62,BBH,-1.64167,0.111618,0.00574527,1.01902 beta-lactamase_2500_K190M,beta-lactamase_2500_190,TEM-1,beta-lactamase_2500,P62593,1.01902,NO,190,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.994,-4.714,2.72,,0.371,H,A,2.34,0.16,29.753,29.753,77.62,BBH,-1.64167,0.361275,0.00574527,1.01902 beta-lactamase_39_K190R,beta-lactamase_39_190,TEM-1,beta-lactamase_39,P62593,1.01902,NO,190,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.994,-2.302,0.308,,0.371,H,A,2.34,0.16,1.513,,77.62,BBH,-1.64167,0.0495842,0.00574527,1.01902 beta-lactamase_39_R162M,beta-lactamase_39_162,TEM-1,beta-lactamase_39,P62593,1.01902,NO,162,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.016,-4.454,3.438,,0.124,S,B,1.2,-0.37,31.656,31.656,64.69,ABH,-1.25,0.0495842,0.000561334,1.01902 beta-lactamase_L218L,beta-lactamase_218,TEM-1,beta-lactamase,P62593,1.01902,NO,218,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.391,-1.391,,4.88972,,I,b,2.89,-0.53,12.788,12.788,74.48,OHH,-1.58867,0.221079,0.00618274,1.01902 kka2_1:2_R202A,kka2_1:2_202,Kka2,kka2_1:2,P00552,1.01903,NO,202,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.761,-2.662,0.901,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.295029,0.00696498,1.01903 beta-lactamase_0_W163R,beta-lactamase_0_163,TEM-1,beta-lactamase_0,P62593,1.01904,NO,163,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-1.843,-2.51,0.667,,0.467,,B,0.47,-0.5,13.843,13.843,63.99,BHA,-1.269,0.0500837,0.00418955,1.01904 beta-lactamase_0_G281E,beta-lactamase_0_281,TEM-1,beta-lactamase_0,P62593,1.01905,NO,281,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.0500837,0.0406482,1.01905 beta-lactamase_156_D99C,beta-lactamase_156_99,TEM-1,beta-lactamase_156,P62593,1.01906,NO,99,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.191,-5.117,3.926,,0.402,G,A,0.75,0.36,3.529,,64.69,PAH,-1.794,0.111618,0.00305446,1.01906 beta-lactamase_39_L28D,beta-lactamase_39_28,TEM-1,beta-lactamase_39,P62593,1.01906,NO,28,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.579,-3.96,2.381,,0.277,H,A,0.55,-0.16,3.262,,93.01,PHH,-2.11333,0.0495842,0.00359321,1.01906 beta-lactamase_625_Q97G,beta-lactamase_625_97,TEM-1,beta-lactamase_625,P62593,1.01906,NO,97,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.072,-2.827,0.755,,0.823,G,A,0.64,2.42,16.954,16.954,77.62,PPP,-2.43833,0.213352,0.0045116,1.01906 beta-lactamase_39_A84N,beta-lactamase_39_84,TEM-1,beta-lactamase_39,P62593,1.01907,NO,84,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.651,-2.768,1.117,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.0495842,0.00503822,1.01907 beta-lactamase_T138T,beta-lactamase_138,TEM-1,beta-lactamase,P62593,1.01907,NO,138,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.506,-2.506,,5.52585,0.662,H,A,0.3,-0.03,30.445,30.445,73.78,HPP,-1.81233,0.221079,0.00487868,1.01907 beta-lactamase_625_A211G,beta-lactamase_625_211,TEM-1,beta-lactamase_625,P62593,1.01908,NO,211,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.896,-2.355,0.459,,0.369,T,A,0.46,-0.69,2.061,,77.62,AHA,-1.94633,0.213352,0.00648183,1.01908 PSD95pdz3_R313D,PSD95pdz3_313,PSD95pdz3,PSD95pdz3,P31016,1.01908,NO,313,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.582,-3.375,1.793,6.63563,,,,,18.3955,,,,BBH,-1.59733,0.0758425,0.000840067,1.01908 WW_domain_D170H,WW_domain_170,Yap65,WW_domain,P46937,1.01908,NO,170,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.213,-4.226,3.013,,,,,,,0.399,,15.87,OAH,-1.38,0.153962,0.00123319,1.01908 beta-lactamase_156_R92P,beta-lactamase_156_92,TEM-1,beta-lactamase_156,P62593,1.01911,NO,92,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.718,-3.033,1.315,,0.479,E,B,1.2,1.36,19.112,19.112,65.38,BBH,-1.50367,0.111618,0.00429626,1.01911 beta-lactamase_625_A183S,beta-lactamase_625_183,TEM-1,beta-lactamase_625,P62593,1.01911,NO,183,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.231,-2.011,0.78,,0.155,H,A,0.46,-0.91,23.859,23.859,77.62,HHH,-1.53367,0.213352,0.00296631,1.01911 beta-lactamase_625_H110G,beta-lactamase_625_110,TEM-1,beta-lactamase_625,P62593,1.01911,NO,110,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-1.706,-3.573,1.867,,0.341,G,a,0.17,1.08,31.31,31.31,64.69,BBH,-1.73333,0.213352,0.00441499,1.01911 beta-lactamase_156_Q86N,beta-lactamase_156_86,TEM-1,beta-lactamase_156,P62593,1.01912,NO,86,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.4,-3.754,1.354,,0.696,S,A,0.64,2.38,27.704,27.704,77.62,OPA,-1.61067,0.111618,0.00450027,1.01912 beta-lactamase_625_E46L,beta-lactamase_625_46,TEM-1,beta-lactamase_625,P62593,1.01914,NO,46,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.94,-2.216,0.276,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.213352,0.00427568,1.01914 beta-lactamase_A148N,beta-lactamase_148,TEM-1,beta-lactamase,P62593,1.01914,NO,148,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.757,-3.701,1.944,5.28111,0.379,H,A,0.52,-0.55,2.117,,72.73,PHH,-1.40167,0.221079,0.00547053,1.01914 beta-lactamase_156_T138D,beta-lactamase_156_138,TEM-1,beta-lactamase_156,P62593,1.01915,NO,138,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.506,-2.325,-0.181,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.111618,0.00487868,1.01915 PSD95pdz3_G335W,PSD95pdz3_335,PSD95pdz3,PSD95pdz3,P31016,1.01915,NO,335,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.008,-4.779,3.771,4.76223,,,,,22.4225,,,,AOH,-1.34733,0.0758425,0.000900493,1.01915 beta-lactamase_156_E279Q,beta-lactamase_156_279,TEM-1,beta-lactamase_156,P62593,1.01917,NO,279,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.111618,0.0192826,1.01917 beta-lactamase_39_R91S,beta-lactamase_39_91,TEM-1,beta-lactamase_39,P62593,1.01917,NO,91,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.392,-3.342,1.95,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.0495842,0.00380226,1.01917 beta-lactamase_625_L192F,beta-lactamase_625_192,TEM-1,beta-lactamase_625,P62593,1.01918,NO,192,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.254,-2.572,1.318,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.213352,0.00558728,1.01918 kka2_1:2_D180V,kka2_1:2_180,Kka2,kka2_1:2,P00552,1.01918,NO,180,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.416,-3.003,0.587,,1.03,S,a,0.75,1.5,1.27,,71.59,OAO,-2.02933,0.295029,0.00756412,1.01918 Pab1_A199G,Pab1_199,Pab1,Pab1,P04147,1.01918,NO,199,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.53,-1.218,-0.312,,,,,,,1.479,,80.42,HHO,-1.50467,0.175299,0.00145024,1.01918 beta-lactamase_39_N274R,beta-lactamase_39_274,TEM-1,beta-lactamase_39,P62593,1.01919,NO,274,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.0495842,0.0110418,1.01919 PSD95pdz3_N369F,PSD95pdz3_369,PSD95pdz3,PSD95pdz3,P31016,1.0192,NO,369,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-1.572,-3.973,2.401,5.91569,,,,,24.1262,0.44,,87.71,BPH,-1.487,0.0758425,0.000608412,1.0192 beta-lactamase_156_I140A,beta-lactamase_156_140,TEM-1,beta-lactamase_156,P62593,1.01922,NO,140,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.733,-3.145,1.412,,0.128,H,A,0.48,0.41,1.16,,73.08,PHO,-1.48733,0.111618,0.00597777,1.01922 beta-lactamase_39_A40W,beta-lactamase_39_40,TEM-1,beta-lactamase_39,P62593,1.01922,NO,40,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.402,-5.298,3.896,,0.155,S,B,0.46,0.21,0.783,,73.78,OHB,-1.40267,0.0495842,0.00490026,1.01922 beta-lactamase_39_R91L,beta-lactamase_39_91,TEM-1,beta-lactamase_39,P62593,1.01922,NO,91,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.392,-3.471,2.079,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.0495842,0.00380226,1.01922 kka2_1:8_A224V,kka2_1:8_224,Kka2,kka2_1:8,P00552,1.01922,NO,224,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.977,-2.571,1.594,,,H,A,0.46,-1.26,0.357,,63.64,HHP,-1.41033,0.100394,0.00352047,1.01922 kka2_1:8_A224V,kka2_1:8_224,Kka2,kka2_1:8,P00552,1.01922,NO,224,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.977,-2.571,1.594,,,H,A,0.46,-1.26,0.357,,63.64,HHP,-1.41033,0.100394,0.00352047,1.01922 beta-lactamase_625_A282M,beta-lactamase_625_282,TEM-1,beta-lactamase_625,P62593,1.01923,NO,282,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.213352,0.0449821,1.01923 beta-lactamase_156_A84F,beta-lactamase_156_84,TEM-1,beta-lactamase_156,P62593,1.01924,NO,84,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.651,-4.366,2.715,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.111618,0.00503822,1.01924 beta-lactamase_39_G85W,beta-lactamase_39_85,TEM-1,beta-lactamase_39,P62593,1.01924,NO,85,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.011,-5.288,4.277,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.0495842,0.00252173,1.01924 beta-lactamase_39_A183R,beta-lactamase_39_183,TEM-1,beta-lactamase_39,P62593,1.01925,NO,183,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.231,-3.825,2.594,,0.155,H,A,0.46,-0.91,1.237,,77.62,HHH,-1.53367,0.0495842,0.00296631,1.01925 beta-lactamase_39_E145I,beta-lactamase_39_145,TEM-1,beta-lactamase_39,P62593,1.01925,NO,145,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.357,-4.11,1.753,,0.545,H,A,1.04,0.79,1.199,,77.62,BAH,-2.069,0.0495842,0.00553285,1.01925 beta-lactamase_39_T69C,beta-lactamase_39_69,TEM-1,beta-lactamase_39,P62593,1.01925,NO,69,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-0.973,-4.661,3.688,,,G,A,0.22,-1.24,4.194,,93.01,PPH,-1.01833,0.0495842,0.00127498,1.01925 beta-lactamase_T126T,beta-lactamase_126,TEM-1,beta-lactamase,P62593,1.01925,NO,126,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.122,-1.122,,4.82694,0.05,H,A,0.3,-0.05,1.14,,44.41,HPH,-1.60467,0.221079,0.00244552,1.01925 beta-lactamase_156_I93W,beta-lactamase_156_93,TEM-1,beta-lactamase_156,P62593,1.01926,NO,93,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.401,-5.418,4.017,,0.128,E,B,0.48,0.44,1.524,,67.83,BHB,-1.873,0.111618,0.00527066,1.01926 beta-lactamase_39_N168H,beta-lactamase_39_168,TEM-1,beta-lactamase_39,P62593,1.01926,NO,168,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-1.029,-4.17,3.141,,0.113,G,A,0.61,-0.4,0.822,,44.41,HPA,-1.13233,0.0495842,0.00288667,1.01926 beta-lactamase_S57A,beta-lactamase_57,TEM-1,beta-lactamase,P62593,1.01927,NO,57,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.918,-1.894,-0.024,5.64201,0.352,E,B,0.25,-0.18,1.971,,72.73,APH,-2.29167,0.221079,0.00492804,1.01927 beta-lactamase_156_L28H,beta-lactamase_156_28,TEM-1,beta-lactamase_156,P62593,1.01928,NO,28,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.579,-4.838,3.259,,0.277,H,A,0.55,-0.16,3.262,,93.01,PHH,-2.11333,0.111618,0.00359321,1.01928 beta-lactamase_156_S283M,beta-lactamase_156_283,TEM-1,beta-lactamase_156,P62593,1.01928,NO,283,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.111618,0.0429138,1.01928 beta-lactamase_2500_V29R,beta-lactamase_2500_29,TEM-1,beta-lactamase_2500,P62593,1.01929,NO,29,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-2.856,-3.682,0.826,,0.733,H,A,0.44,-0.78,1.931,,93.01,HHB,-2.24733,0.361275,0.00318969,1.01929 beta-lactamase_625_Q88L,beta-lactamase_625_88,TEM-1,beta-lactamase_625,P62593,1.01929,NO,88,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.086,-3.504,1.418,,0.807,,B,0.64,2.03,1.84,,77.62,APH,-1.53433,0.213352,0.00504167,1.01929 beta-lactamase_39_L219W,beta-lactamase_39_219,TEM-1,beta-lactamase_39,P62593,1.0193,NO,219,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.313,-5.183,3.87,,,I,A,0.55,-0.51,19.842,19.842,74.48,HHB,-1.21533,0.0495842,0.00664345,1.0193 PSD95pdz3_G383A,PSD95pdz3_383,PSD95pdz3,PSD95pdz3,P31016,1.0193,NO,383,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.008,-2.534,1.526,5.17213,,,,,20.5325,,,,HOP,-1.338,0.0758425,0.000233044,1.0193 beta-lactamase_156_E145Q,beta-lactamase_156_145,TEM-1,beta-lactamase_156,P62593,1.01931,NO,145,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.357,-2.979,0.622,,0.545,H,A,1.04,0.79,3.661,,77.62,BAH,-2.069,0.111618,0.00553285,1.01931 beta-lactamase_39_A278F,beta-lactamase_39_278,TEM-1,beta-lactamase_39,P62593,1.01931,NO,278,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.0495842,0.0310297,1.01931 beta-lactamase_39_G141Q,beta-lactamase_39_141,TEM-1,beta-lactamase_39,P62593,1.01933,NO,141,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.828,-3.982,3.154,,0.575,T,l,0.29,-0.28,0.722,,64.69,HOO,-1.08933,0.0495842,0.0012419,1.01933 beta-lactamase_V21A,beta-lactamase_21,TEM-1,beta-lactamase,P62593,1.01933,NO,21,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.873,-1.474,-0.399,,,,,,,0.688,,93.01,OHH,-2.09633,0.221079,0.0028612,1.01933 beta-lactamase_156_S80Q,beta-lactamase_156_80,TEM-1,beta-lactamase_156,P62593,1.01934,NO,80,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.029,-3.941,1.912,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.111618,0.00565569,1.01934 beta-lactamase_Q97M,beta-lactamase_97,TEM-1,beta-lactamase,P62593,1.01935,NO,97,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.072,-3.413,1.341,6.30204,0.823,G,A,1.1,2.42,1.157,,77.62,PPP,-2.43833,0.221079,0.0045116,1.01935 kka2_1:8_T28D,kka2_1:8_28,Kka2,kka2_1:8,P00552,1.01935,NO,28,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.883,-2.685,0.802,,0.353,S,B,0.22,2.02,18.114,18.114,63.64,PPH,-1.74467,0.100394,0.00743084,1.01935 kka2_1:8_T28D,kka2_1:8_28,Kka2,kka2_1:8,P00552,1.01935,NO,28,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.883,-2.685,0.802,,0.353,S,B,0.22,2.02,18.114,18.114,63.64,PPH,-1.74467,0.100394,0.00743084,1.01935 beta-lactamase_156_S221Q,beta-lactamase_156_221,TEM-1,beta-lactamase_156,P62593,1.01936,NO,221,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.754,-3.871,2.117,,0.624,H,A,0.27,-0.2,17.729,17.729,74.48,BPH,-1.59967,0.111618,0.0046094,1.01936 beta-lactamase_39_V82W,beta-lactamase_39_82,TEM-1,beta-lactamase_39,P62593,1.01936,NO,82,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.325,-5.421,4.096,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.0495842,0.00397046,1.01936 beta-lactamase_39_S104H,beta-lactamase_39_104,TEM-1,beta-lactamase_39,P62593,1.01937,NO,104,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.015,-4.582,3.567,,0.04,,b,0.27,0.57,4.02,,63.29,HPO,-1.05267,0.0495842,0.00218083,1.01937 kka2_1:2_R173N,kka2_1:2_173,Kka2,kka2_1:2,P00552,1.01939,NO,173,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.407,-3.101,0.694,,0.308,H,A,0.16,-0.13,15.389,15.389,65.53,HBH,-1.70533,0.295029,0.00784999,1.01939 PSD95pdz3_E352G,PSD95pdz3_352,PSD95pdz3,PSD95pdz3,P31016,1.01939,NO,352,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.587,-2.93,1.343,5.49659,,,,,24.2,2.525,,86.88,OAH,-1.314,0.0758425,0.000892231,1.01939 beta-lactamase_156_T187W,beta-lactamase_156_187,TEM-1,beta-lactamase_156,P62593,1.0194,NO,187,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.401,-5.371,3.97,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.111618,0.00491782,1.0194 WW_domain_S184W,WW_domain_184,Yap65,WW_domain,P46937,1.0194,NO,184,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.363,-5.093,3.73,5.06696,,,,,,,,,PPO,-1.39133,0.153962,0.00231095,1.0194 beta-lactamase_0_L137I,beta-lactamase_0_137,TEM-1,beta-lactamase_0,P62593,1.01941,NO,137,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.03,-2.064,1.034,,,H,A,0.55,-0.38,0.328,,42.31,HHP,-1.58933,0.0500837,0.00278599,1.01941 beta-lactamase_156_D36V,beta-lactamase_156_36,TEM-1,beta-lactamase_156,P62593,1.01941,NO,36,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.732,-3.726,0.994,,0.555,H,A,0.75,1.17,14.871,14.871,77.62,AAP,-1.91167,0.111618,0.00476483,1.01941 beta-lactamase_39_A282I,beta-lactamase_39_282,TEM-1,beta-lactamase_39,P62593,1.01941,NO,282,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.0495842,0.0449821,1.01941 Pab1_A158C,Pab1_158,Pab1,Pab1,P04147,1.01941,NO,158,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.154,-4.333,3.179,,,,,,,1.197,,56.33,HHP,-1.40733,0.175299,0.000649733,1.01941 beta-lactamase_39_S221L,beta-lactamase_39_221,TEM-1,beta-lactamase_39,P62593,1.01942,NO,221,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.754,-3.35,1.596,,0.624,H,A,0.27,-0.2,2.69,,74.48,BPH,-1.59967,0.0495842,0.0046094,1.01942 beta-lactamase_L196E,beta-lactamase_196,TEM-1,beta-lactamase,P62593,1.01942,NO,196,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-2.478,-3.033,0.555,,0.518,S,A,0.55,1.35,,,77.62,AHH,-1.839,0.221079,0.00512144,1.01942 beta-lactamase_156_L74C,beta-lactamase_156_74,TEM-1,beta-lactamase_156,P62593,1.01943,NO,74,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.296,-4.647,3.351,,,H,A,0.55,-0.91,0.746,,50,HHO,-1.34933,0.111618,0.00493255,1.01943 beta-lactamase_39_R41D,beta-lactamase_39_41,TEM-1,beta-lactamase_39,P62593,1.01943,NO,41,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-0.942,-3.657,2.715,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.0495842,0.00123327,1.01943 beta-lactamase_39_T131L,beta-lactamase_39_131,TEM-1,beta-lactamase_39,P62593,1.01943,NO,131,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.328,-3.319,1.991,,,H,A,0.22,-0.69,3.306,,67.48,PPH,-1.00867,0.0495842,0.00345886,1.01943 beta-lactamase_156_M270V,beta-lactamase_156_270,TEM-1,beta-lactamase_156,P62593,1.01945,NO,270,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.111618,0.00767762,1.01945 beta-lactamase_625_Q88N,beta-lactamase_625_88,TEM-1,beta-lactamase_625,P62593,1.01949,NO,88,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.086,-2.735,0.649,,0.807,,B,0.64,2.03,1.84,,77.62,APH,-1.53433,0.213352,0.00504167,1.01949 beta-lactamase_39_E26A,beta-lactamase_39_26,TEM-1,beta-lactamase_39,P62593,1.0195,NO,26,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.454,-2.207,-0.247,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.0495842,0.00297948,1.0195 beta-lactamase_39_L167P,beta-lactamase_39_167,TEM-1,beta-lactamase_39,P62593,1.0195,NO,167,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.138,-4.076,2.938,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.0495842,0.00303566,1.0195 beta-lactamase_39_D174S,beta-lactamase_39_174,TEM-1,beta-lactamase_39,P62593,1.01951,NO,174,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.738,-3.161,2.423,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.0495842,0.00125633,1.01951 beta-lactamase_39_P224R,beta-lactamase_39_224,TEM-1,beta-lactamase_39,P62593,1.01951,NO,224,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.893,-2.763,1.87,,0.383,,B,0.52,-0.3,3.169,,74.48,HOH,-1.26433,0.0495842,0.00189564,1.01951 beta-lactamase_39_T187H,beta-lactamase_39_187,TEM-1,beta-lactamase_39,P62593,1.01951,NO,187,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.401,-4.688,3.287,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.0495842,0.00491782,1.01951 beta-lactamase_2500_Q86T,beta-lactamase_2500_86,TEM-1,beta-lactamase_2500,P62593,1.01953,NO,86,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.4,-2.587,0.187,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.361275,0.00450027,1.01953 kka2_1:8_P98M,kka2_1:8_98,Kka2,kka2_1:8,P00552,1.01953,NO,98,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.526,-4.804,3.278,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.100394,0.00622754,1.01953 kka2_1:8_P98M,kka2_1:8_98,Kka2,kka2_1:8,P00552,1.01953,NO,98,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.526,-4.804,3.278,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.100394,0.00622754,1.01953 beta-lactamase_39_G240F,beta-lactamase_39_240,TEM-1,beta-lactamase_39,P62593,1.01954,NO,240,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.0495842,0.00591201,1.01954 kka2_1:8_R145C,kka2_1:8_145,Kka2,kka2_1:8,P00552,1.01955,NO,145,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.804,-5.218,3.414,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.100394,0.00846663,1.01955 kka2_1:8_R145C,kka2_1:8_145,Kka2,kka2_1:8,P00552,1.01955,NO,145,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.804,-5.218,3.414,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.100394,0.00846663,1.01955 beta-lactamase_156_E195H,beta-lactamase_156_195,TEM-1,beta-lactamase_156,P62593,1.01956,NO,195,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.186,-3.381,1.195,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.111618,0.00496565,1.01956 beta-lactamase_D36T,beta-lactamase_36,TEM-1,beta-lactamase,P62593,1.01956,NO,36,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.732,-2.57,-0.162,5.39764,0.555,H,A,0.11,1.17,13.689,13.689,77.62,AAP,-1.91167,0.221079,0.00476483,1.01956 beta-lactamase_N173Q,beta-lactamase_173,TEM-1,beta-lactamase,P62593,1.01956,NO,173,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-2.663,-4.003,1.34,7.02497,1.044,T,l,0.09,1.25,1.88,,77.62,OPA,-1.46633,0.221079,0.0033769,1.01956 beta-lactamase_39_R92Q,beta-lactamase_39_92,TEM-1,beta-lactamase_39,P62593,1.01957,NO,92,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.718,-3.029,1.311,,0.479,E,B,1.2,1.36,0.389,,65.38,BBH,-1.50367,0.0495842,0.00429626,1.01957 beta-lactamase_39_V29S,beta-lactamase_39_29,TEM-1,beta-lactamase_39,P62593,1.01957,NO,29,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-2.856,-2.693,-0.163,,0.733,H,A,0.44,-0.78,1.287,,93.01,HHB,-2.24733,0.0495842,0.00318969,1.01957 WW_domain_L173M,WW_domain_173,Yap65,WW_domain,P46937,1.01957,NO,173,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.117,-3.582,2.465,,,,,,,,,,OHO,-1.06233,0.153962,0.000851849,1.01957 beta-lactamase_625_H151I,beta-lactamase_625_151,TEM-1,beta-lactamase_625,P62593,1.01958,NO,151,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-2.96,-4.091,1.131,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.213352,0.00216946,1.01958 PSD95pdz3_G351Q,PSD95pdz3_351,PSD95pdz3,PSD95pdz3,P31016,1.01958,NO,351,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.008,-3.806,2.798,5.44798,,,,,20.7625,,,,POA,-1.37133,0.0758425,0.000691282,1.01958 beta-lactamase_0_Q37V,beta-lactamase_0_37,TEM-1,beta-lactamase_0,P62593,1.01959,NO,37,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.134,-3.664,1.53,,0.613,H,A,0.64,1.98,4.001,,73.08,APH,-2.06967,0.0500837,0.00425833,1.01959 beta-lactamase_39_I140F,beta-lactamase_39_140,TEM-1,beta-lactamase_39,P62593,1.01959,NO,140,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.733,-2.91,1.177,,0.128,H,A,0.48,0.41,1.16,,73.08,PHO,-1.48733,0.0495842,0.00597777,1.01959 beta-lactamase_156_E108H,beta-lactamase_156_108,TEM-1,beta-lactamase_156,P62593,1.0196,NO,108,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.46,-4.53,3.07,,0.572,G,A,1.04,1.87,8.602,8.602,72.73,PAB,-1.437,0.111618,0.00413372,1.0196 beta-lactamase_2500_T186C,beta-lactamase_2500_186,TEM-1,beta-lactamase_2500,P62593,1.0196,NO,186,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.522,-5.021,2.499,,0.396,H,A,0.22,-0.28,2.144,,77.62,HPP,-1.77633,0.361275,0.00485034,1.0196 beta-lactamase_625_E35A,beta-lactamase_625_35,TEM-1,beta-lactamase_625,P62593,1.0196,NO,35,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-0.869,-3.127,2.258,,0.15,H,A,1.04,0.21,0.664,,46.85,HAA,-1.88667,0.213352,0.00174441,1.0196 beta-lactamase_156_I171E,beta-lactamase_156_171,TEM-1,beta-lactamase_156,P62593,1.01961,NO,171,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-2.431,-3.643,1.212,,0.361,,B,0.48,0.53,3.869,,77.62,HHO,-1.55533,0.111618,0.00623355,1.01961 beta-lactamase_39_T138W,beta-lactamase_39_138,TEM-1,beta-lactamase_39,P62593,1.01961,NO,138,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.506,-5.551,3.045,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.0495842,0.00487868,1.01961 beta-lactamase_625_I258V,beta-lactamase_625_258,TEM-1,beta-lactamase_625,P62593,1.01961,NO,258,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.975,-2.547,0.572,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.213352,0.007931,1.01961 beta-lactamase_625_Q88M,beta-lactamase_625_88,TEM-1,beta-lactamase_625,P62593,1.01961,NO,88,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.086,-3.418,1.332,,0.807,,B,0.64,2.03,1.84,,77.62,APH,-1.53433,0.213352,0.00504167,1.01961 kka2_1:4_E235N,kka2_1:4_235,Kka2,kka2_1:4,P00552,1.01961,NO,235,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.955,-3.12,1.165,,0.631,H,A,1.04,0.12,23.175,23.175,65.53,OAH,-2.07267,0.168804,0.0102806,1.01961 kka2_1:8_L232C,kka2_1:8_232,Kka2,kka2_1:8,P00552,1.01961,NO,232,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.514,-3.424,1.91,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.100394,0.00800103,1.01961 kka2_1:8_L232C,kka2_1:8_232,Kka2,kka2_1:8,P00552,1.01961,NO,232,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.514,-3.424,1.91,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.100394,0.00800103,1.01961 beta-lactamase_0_G142M,beta-lactamase_0_142,TEM-1,beta-lactamase_0,P62593,1.01962,NO,142,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.707,-4.893,4.186,,0.034,,p,0.29,-0.64,1.947,,64.69,OOO,-0.834,0.0500837,0.00060149,1.01962 beta-lactamase_39_S51V,beta-lactamase_39_51,TEM-1,beta-lactamase_39,P62593,1.01962,NO,51,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.526,-3.559,2.033,,0.496,T,A,0.27,0.26,2.964,,72.73,PPO,-1.88467,0.0495842,0.00504821,1.01962 beta-lactamase_0_E175M,beta-lactamase_0_175,TEM-1,beta-lactamase_0,P62593,1.01963,NO,175,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.336,-3.397,1.061,,0.551,,A,1.04,1.05,2.334,,77.62,AAB,-1.31233,0.0500837,0.00482205,1.01963 beta-lactamase_0_F228M,beta-lactamase_0_228,TEM-1,beta-lactamase_0,P62593,1.01964,NO,228,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-2.342,-3.369,1.027,,0.154,E,B,0.58,-0.42,15.504,15.504,63.29,HHH,-1.53033,0.0500837,0.0046669,1.01964 beta-lactamase_39_L47E,beta-lactamase_39_47,TEM-1,beta-lactamase_39,P62593,1.01964,NO,47,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.876,-2.999,1.123,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.0495842,0.00439844,1.01964 beta-lactamase_39_M66S,beta-lactamase_39_66,TEM-1,beta-lactamase_39,P62593,1.01964,NO,66,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.362,-3.571,2.209,,0.013,,A,0.55,-0.7,1.319,,73.08,OHH,-1.49567,0.0495842,0.00412876,1.01964 beta-lactamase_625_P60I,beta-lactamase_625_60,TEM-1,beta-lactamase_625,P62593,1.01964,NO,60,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-2.469,-3.895,1.426,,0.256,T,A,0.52,-0.56,3.653,,77.62,BOA,-1.97633,0.213352,0.00521318,1.01964 beta-lactamase_39_L38K,beta-lactamase_39_38,TEM-1,beta-lactamase_39,P62593,1.01965,NO,38,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.343,-3.749,2.406,,0.088,H,A,0.55,0.2,17.089,17.089,64.34,PHO,-1.78033,0.0495842,0.00373244,1.01965 beta-lactamase_E237G,beta-lactamase_237,TEM-1,beta-lactamase,P62593,1.01965,NO,237,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.058,-1.939,-0.119,5.42877,0.583,S,B,1.62,1.2,2.144,,77.62,OAB,-1.61467,0.221079,0.0048626,1.01965 kka2_1:2_E111I,kka2_1:2_111,Kka2,kka2_1:2,P00552,1.01965,NO,111,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.28,-4.031,1.751,,0.155,H,A,1.52,-1.14,2.792,,65.53,HAB,-2.27833,0.295029,0.00746789,1.01965 kka2_1:8_A41C,kka2_1:8_41,Kka2,kka2_1:8,P00552,1.01965,NO,41,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.879,-3.65,1.771,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.100394,0.00543332,1.01965 kka2_1:8_A41C,kka2_1:8_41,Kka2,kka2_1:8,P00552,1.01965,NO,41,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.879,-3.65,1.771,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.100394,0.00543332,1.01965 Pab1_H134N,Pab1_134,Pab1,Pab1,P04147,1.01965,NO,134,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-1.542,-2.221,0.679,,,,,,,,,,HBO,-1.346,0.175299,0.00116356,1.01965 beta-lactamase_39_I285W,beta-lactamase_39_285,TEM-1,beta-lactamase_39,P62593,1.01967,NO,285,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.0495842,0.101555,1.01967 Pab1_G167L,Pab1_167,Pab1,Pab1,P04147,1.01967,NO,167,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.223,-3.433,2.21,,0.195,S,g,,0.03,,,,BOH,-1.25133,0.175299,0.00146449,1.01967 beta-lactamase_156_P165K,beta-lactamase_156_165,TEM-1,beta-lactamase_156,P62593,1.01968,NO,165,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.373,-3.528,2.155,,0.203,T,A,0.52,-0.31,3.907,,73.78,AOA,-1.359,0.111618,0.00549538,1.01968 beta-lactamase_625_S241E,beta-lactamase_625_241,TEM-1,beta-lactamase_625,P62593,1.01969,NO,241,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.213352,0.00452736,1.01969 beta-lactamase_0_D207N,beta-lactamase_0_207,TEM-1,beta-lactamase_0,P62593,1.0197,NO,207,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.064,-2.966,0.902,,0.409,H,A,0.75,0.12,5.277,,77.62,HAH,-1.77033,0.0500837,0.00592942,1.0197 beta-lactamase_156_T131F,beta-lactamase_156_131,TEM-1,beta-lactamase_156,P62593,1.0197,NO,131,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.328,-4.204,2.876,,,H,A,0.22,-0.69,2.031,,67.48,PPH,-1.00867,0.111618,0.00345886,1.0197 beta-lactamase_156_E26Q,beta-lactamase_156_26,TEM-1,beta-lactamase_156,P62593,1.01971,NO,26,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.454,-2.296,-0.158,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.111618,0.00297948,1.01971 beta-lactamase_156_K144H,beta-lactamase_156_144,TEM-1,beta-lactamase_156,P62593,1.01971,NO,144,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-2.388,-3.395,1.007,,0.863,H,A,2.34,1.27,2.073,,77.62,OBA,-1.904,0.111618,0.00481141,1.01971 PSD95pdz3_G344W,PSD95pdz3_344,PSD95pdz3,PSD95pdz3,P31016,1.01972,NO,344,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.008,-4.779,3.771,4.83855,,,,,14.06,,,,HOO,-1.10767,0.0758425,0.00078498,1.01972 beta-lactamase_156_E195T,beta-lactamase_156_195,TEM-1,beta-lactamase_156,P62593,1.01973,NO,195,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.186,-2.956,0.77,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.111618,0.00496565,1.01973 beta-lactamase_D36W,beta-lactamase_36,TEM-1,beta-lactamase,P62593,1.01974,NO,36,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.732,-5.422,2.69,5.39764,0.555,H,A,0.11,1.17,13.689,13.689,77.62,AAP,-1.91167,0.221079,0.00476483,1.01974 beta-lactamase_E270D,beta-lactamase_270,TEM-1,beta-lactamase,P62593,1.01974,NO,270,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.723,-2.384,0.661,5.33196,0.422,H,A,0.52,1.15,1.745,,64.34,AAB,-1.70933,0.221079,0.00767762,1.01974 beta-lactamase_L247M,beta-lactamase_247,TEM-1,beta-lactamase,P62593,1.01974,NO,247,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.48,-3.063,1.583,5.28771,0.007,E,B,2.89,-0.72,2.951,,63.99,HHO,-1.79833,0.221079,0.00611275,1.01974 beta-lactamase_156_A230C,beta-lactamase_156_230,TEM-1,beta-lactamase_156,P62593,1.01975,NO,230,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.154,-4.695,3.541,,0.01,E,B,0.46,-1.17,2.179,,50,HHA,-1.079,0.111618,0.00516841,1.01975 beta-lactamase_39_R63K,beta-lactamase_39_63,TEM-1,beta-lactamase_39,P62593,1.01977,NO,63,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-0.943,-2.877,1.934,,0.218,,B,1.2,-0.31,0.326,,44.06,ABH,-0.992333,0.0495842,0.00126938,1.01977 beta-lactamase_156_R118S,beta-lactamase_156_118,TEM-1,beta-lactamase_156,P62593,1.01978,NO,118,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.413,-2.394,-0.019,,0.457,H,A,1.2,1.39,2.231,,77.62,HBA,-1.785,0.111618,0.00538794,1.01978 beta-lactamase_39_T186Q,beta-lactamase_39_186,TEM-1,beta-lactamase_39,P62593,1.01978,NO,186,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.522,-2.514,-0.008,,0.396,H,A,0.22,-0.28,0.515,,77.62,HPP,-1.77633,0.0495842,0.00485034,1.01978 beta-lactamase_2500_E238D,beta-lactamase_2500_238,TEM-1,beta-lactamase_2500,P62593,1.01979,NO,238,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.361275,0.00743256,1.01979 beta-lactamase_39_T126L,beta-lactamase_39_126,TEM-1,beta-lactamase_39,P62593,1.01979,NO,126,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.122,-3.373,2.251,,0.05,H,A,0.22,-0.05,0.586,,44.41,HPH,-1.60467,0.0495842,0.00244552,1.01979 beta-lactamase_39_Q267I,beta-lactamase_39_267,TEM-1,beta-lactamase_39,P62593,1.01982,NO,267,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.0495842,0.0102128,1.01982 beta-lactamase_39_D174H,beta-lactamase_39_174,TEM-1,beta-lactamase_39,P62593,1.01983,NO,174,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.738,-4.455,3.717,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.0495842,0.00125633,1.01983 kka2_1:4_V46K,kka2_1:4_46,Kka2,kka2_1:4,P00552,1.01983,NO,46,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-2.62,-3.127,0.507,,0.192,.,B,0.44,-1.12,9.564,,92.05,OHH,-1.88633,0.168804,0.00631301,1.01983 beta-lactamase_39_A235F,beta-lactamase_39_235,TEM-1,beta-lactamase_39,P62593,1.01984,NO,235,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.266,-4.199,2.933,,0.32,E,B,0.46,-0.86,1.344,,50,OHO,-0.89,0.0495842,0.00493474,1.01984 kka2_1:2_Q26F,kka2_1:2_26,Kka2,kka2_1:2,P00552,1.01984,NO,26,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.18,-4.426,2.246,,0.448,E,B,0.4,0.44,5.022,,92.05,HPP,-2.11167,0.295029,0.00708962,1.01984 beta-lactamase_156_R220T,beta-lactamase_156_220,TEM-1,beta-lactamase_156,P62593,1.01985,NO,220,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-0.942,-3.419,2.477,,0.295,I,A,1.2,-0.76,2.164,,74.48,HBP,-1.33633,0.111618,0.00232421,1.01985 beta-lactamase_156_M270T,beta-lactamase_156_270,TEM-1,beta-lactamase_156,P62593,1.01986,NO,270,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.111618,0.00767762,1.01986 beta-lactamase_156_D36M,beta-lactamase_156_36,TEM-1,beta-lactamase_156,P62593,1.01987,NO,36,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.732,-4.763,2.031,,0.555,H,A,0.75,1.17,14.871,14.871,77.62,AAP,-1.91167,0.111618,0.00476483,1.01987 beta-lactamase_156_E166M,beta-lactamase_156_166,TEM-1,beta-lactamase_156,P62593,1.01987,NO,166,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.756,-4.707,2.951,,0.508,G,A,1.04,1.05,2.393,,73.08,OAH,-1.42233,0.111618,0.00512989,1.01987 beta-lactamase_156_S80D,beta-lactamase_156_80,TEM-1,beta-lactamase_156,P62593,1.01988,NO,80,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.029,-2.7,0.671,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.111618,0.00565569,1.01988 beta-lactamase_625_F149M,beta-lactamase_625_149,TEM-1,beta-lactamase_625,P62593,1.01988,NO,149,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.299,-4.454,3.155,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.213352,0.00418462,1.01988 beta-lactamase_2500_E166Y,beta-lactamase_2500_166,TEM-1,beta-lactamase_2500,P62593,1.01989,NO,166,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.756,-4.36,2.604,,0.508,G,A,1.04,1.05,2.124,,73.08,OAH,-1.42233,0.361275,0.00512989,1.01989 beta-lactamase_39_L248M,beta-lactamase_39_248,TEM-1,beta-lactamase_39,P62593,1.01989,NO,248,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.0495842,0.00428493,1.01989 beta-lactamase_156_R92K,beta-lactamase_156_92,TEM-1,beta-lactamase_156,P62593,1.0199,NO,92,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.718,-2.258,0.54,,0.479,E,B,1.2,1.36,19.112,19.112,65.38,BBH,-1.50367,0.111618,0.00429626,1.0199 beta-lactamase_39_I280C,beta-lactamase_39_280,TEM-1,beta-lactamase_39,P62593,1.0199,NO,280,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.0495842,0.0530888,1.0199 beta-lactamase_2500_E272Q,beta-lactamase_2500_272,TEM-1,beta-lactamase_2500,P62593,1.01991,NO,272,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.361275,0.00545371,1.01991 beta-lactamase_625_E195H,beta-lactamase_625_195,TEM-1,beta-lactamase_625,P62593,1.01991,NO,195,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.186,-3.381,1.195,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.213352,0.00496565,1.01991 beta-lactamase_C121C,beta-lactamase_121,TEM-1,beta-lactamase,P62593,1.01991,NO,121,C,C,CC,Special,Special,5.07,5.07,0,0,121,121,0,108.5,108.5,0,-0.953,-0.953,,5.12205,,H,A,2.8,-0.81,7.644,,63.29,HOP,-1.46767,0.221079,0.000744322,1.01991 beta-lactamase_Q37A,beta-lactamase_37,TEM-1,beta-lactamase,P62593,1.01991,NO,37,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.134,-2.542,0.408,5.69153,0.613,H,A,0.12,1.98,1.318,,73.08,APH,-2.06967,0.221079,0.00425833,1.01991 beta-lactamase_39_G85I,beta-lactamase_39_85,TEM-1,beta-lactamase_39,P62593,1.01992,NO,85,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.011,-4.226,3.215,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.0495842,0.00252173,1.01992 beta-lactamase_39_L223W,beta-lactamase_39_223,TEM-1,beta-lactamase_39,P62593,1.01992,NO,223,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.055,-5.101,4.046,,0.27,,B,0.55,0.09,1.511,,74.48,HHO,-1.35033,0.0495842,0.00372793,1.01992 beta-lactamase_625_L49A,beta-lactamase_625_49,TEM-1,beta-lactamase_625,P62593,1.01992,NO,49,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.897,-3.125,1.228,,0.131,T,A,0.55,0.04,3.112,,64.69,AHP,-1.99233,0.213352,0.00401477,1.01992 beta-lactamase_S254A,beta-lactamase_254,TEM-1,beta-lactamase,P62593,1.01993,NO,254,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.126,-2.519,0.393,5.49575,0.312,,a,0.25,-0.48,24.91,24.91,69.58,OPB,-2.215,0.221079,0.00369,1.01993 beta-lactamase_0_G216H,beta-lactamase_0_216,TEM-1,beta-lactamase_0,P62593,1.01994,NO,216,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.477,-4.598,3.121,,0.437,I,A,0.29,-0.58,0.834,,74.48,HOO,-1.68067,0.0500837,0.00639568,1.01994 beta-lactamase_39_E108W,beta-lactamase_39_108,TEM-1,beta-lactamase_39,P62593,1.01994,NO,108,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.46,-5.465,4.005,,0.572,G,A,1.04,1.87,20.151,20.151,72.73,PAB,-1.437,0.0495842,0.00413372,1.01994 beta-lactamase_39_V157I,beta-lactamase_39_157,TEM-1,beta-lactamase_39,P62593,1.01994,NO,157,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.751,-2.621,0.87,,0.308,S,a,0.44,-0.75,10.364,10.364,69.58,BHP,-2.00767,0.0495842,0.00506849,1.01994 beta-lactamase_A148S,beta-lactamase_148,TEM-1,beta-lactamase,P62593,1.01995,NO,148,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.757,-2.791,1.034,5.28111,0.379,H,A,0.52,-0.55,2.117,,72.73,PHH,-1.40167,0.221079,0.00547053,1.01995 gb1_Q228N,gb1_228,gb1,gb1,P06654,1.01995,NO,228,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,,,,,,,,,,,,,OPH,-1.282,0.177985,0.00391043,1.01995 beta-lactamase_625_H110R,beta-lactamase_625_110,TEM-1,beta-lactamase_625,P62593,1.01996,NO,110,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-1.706,-2.008,0.302,,0.341,G,a,0.17,1.08,31.31,31.31,64.69,BBH,-1.73333,0.213352,0.00441499,1.01996 beta-lactamase_156_T139E,beta-lactamase_156_139,TEM-1,beta-lactamase_156,P62593,1.01997,NO,139,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.901,-2.44,0.539,,0.216,H,A,0.22,0.39,16.34,16.34,77.62,PPH,-2.04667,0.111618,0.00441837,1.01997 beta-lactamase_E210I,beta-lactamase_210,TEM-1,beta-lactamase,P62593,1.01997,NO,210,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.319,-2.456,0.137,5.7398,0.476,H,A,0.52,0.75,1.555,,77.62,HAH,-1.88567,0.221079,0.00663582,1.01997 beta-lactamase_I206L,beta-lactamase_206,TEM-1,beta-lactamase,P62593,1.01997,NO,206,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-2.429,-2.261,-0.168,5.3727,0.173,H,A,1,-0.34,2.061,,77.62,HHA,-1.805,0.221079,0.00528934,1.01997 PSD95pdz3_G319C,PSD95pdz3_319,PSD95pdz3,PSD95pdz3,P31016,1.01997,NO,319,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.008,-4.769,3.761,4.95387,,,,,18.8725,,,,BOP,-1.36967,0.0758425,0.00109317,1.01997 beta-lactamase_39_L28A,beta-lactamase_39_28,TEM-1,beta-lactamase_39,P62593,1.01999,NO,28,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.579,-2.126,0.547,,0.277,H,A,0.55,-0.16,3.262,,93.01,PHH,-2.11333,0.0495842,0.00359321,1.01999 beta-lactamase_625_V29T,beta-lactamase_625_29,TEM-1,beta-lactamase_625,P62593,1.01999,NO,29,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-2.856,-2.552,-0.304,,0.733,H,A,0.44,-0.78,1.931,,93.01,HHB,-2.24733,0.213352,0.00318969,1.01999 beta-lactamase_39_A148I,beta-lactamase_39_148,TEM-1,beta-lactamase_39,P62593,1.02,NO,148,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.757,-4.049,2.292,,0.379,H,A,0.46,-0.55,3.551,,72.73,PHH,-1.40167,0.0495842,0.00547053,1.02 beta-lactamase_39_G141H,beta-lactamase_39_141,TEM-1,beta-lactamase_39,P62593,1.02,NO,141,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.828,-4.652,3.824,,0.575,T,l,0.29,-0.28,0.722,,64.69,HOO,-1.08933,0.0495842,0.0012419,1.02 beta-lactamase_39_R63V,beta-lactamase_39_63,TEM-1,beta-lactamase_39,P62593,1.02,NO,63,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-0.943,-3.626,2.683,,0.218,,B,1.2,-0.31,0.326,,44.06,ABH,-0.992333,0.0495842,0.00126938,1.02 beta-lactamase_39_A183I,beta-lactamase_39_183,TEM-1,beta-lactamase_39,P62593,1.02001,NO,183,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.231,-2.835,1.604,,0.155,H,A,0.46,-0.91,1.237,,77.62,HHH,-1.53367,0.0495842,0.00296631,1.02001 beta-lactamase_R118G,beta-lactamase_118,TEM-1,beta-lactamase,P62593,1.02001,NO,118,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.413,-1.757,-0.656,5.8227,0.457,H,A,0.68,1.39,2.144,,77.62,HBA,-1.785,0.221079,0.00538794,1.02001 kka2_1:8_L232Y,kka2_1:8_232,Kka2,kka2_1:8,P00552,1.02001,NO,232,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.514,-3.053,1.539,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.100394,0.00800103,1.02001 kka2_1:8_L232Y,kka2_1:8_232,Kka2,kka2_1:8,P00552,1.02001,NO,232,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.514,-3.053,1.539,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.100394,0.00800103,1.02001 beta-lactamase_A225N,beta-lactamase_225,TEM-1,beta-lactamase,P62593,1.02002,NO,225,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.845,-3.051,1.206,6.5181,1,T,B,0.58,-0.38,4.077,,74.48,OHO,-1.39967,0.221079,0.00465057,1.02002 beta-lactamase_39_F58R,beta-lactamase_39_58,TEM-1,beta-lactamase_39,P62593,1.02003,NO,58,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-2.914,-2.758,-0.156,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.0495842,0.00523369,1.02003 beta-lactamase_F58F,beta-lactamase_58,TEM-1,beta-lactamase,P62593,1.02003,NO,58,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-2.914,-2.914,,5.55634,0.266,E,B,1.33,-0.07,2.467,,77.62,PHB,-2.059,0.221079,0.00523369,1.02003 beta-lactamase_R92V,beta-lactamase_92,TEM-1,beta-lactamase,P62593,1.02003,NO,92,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.718,-2.509,0.791,5.65832,0.479,E,B,0.91,1.36,3.069,,65.38,BBH,-1.50367,0.221079,0.00429626,1.02003 kka2_1:8_W24T,kka2_1:8_24,Kka2,kka2_1:8,P00552,1.02003,NO,24,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-1.779,-3.697,1.918,,0.477,E,B,1.51,-0.21,2.503,,56.06,AHH,-2.24467,0.100394,0.00631564,1.02003 kka2_1:8_W24T,kka2_1:8_24,Kka2,kka2_1:8,P00552,1.02003,NO,24,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-1.779,-3.697,1.918,,0.477,E,B,1.51,-0.21,2.503,,56.06,AHH,-2.24467,0.100394,0.00631564,1.02003 beta-lactamase_156_A215T,beta-lactamase_156_215,TEM-1,beta-lactamase_156,P62593,1.02005,NO,215,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.503,-2.291,0.788,,,,a,0.46,-0.93,3.583,,74.48,HHO,-1.42633,0.111618,0.00544007,1.02005 beta-lactamase_625_K109M,beta-lactamase_625_109,TEM-1,beta-lactamase_625,P62593,1.02005,NO,109,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.734,-4.742,3.008,,0.787,G,A,2.34,2.21,7.243,,72.73,ABB,-1.63333,0.213352,0.00462493,1.02005 PSD95pdz3_A378G,PSD95pdz3_378,PSD95pdz3,PSD95pdz3,P31016,1.02005,NO,378,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.307,-2.59,1.283,4.86582,,,,,14.576,,,,HHH,-1.509,0.0758425,0.000313169,1.02005 beta-lactamase_156_K30T,beta-lactamase_156_30,TEM-1,beta-lactamase_156,P62593,1.02006,NO,30,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-2.307,-2.199,-0.108,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.111618,0.00448593,1.02006 beta-lactamase_39_W227F,beta-lactamase_39_227,TEM-1,beta-lactamase_39,P62593,1.02006,NO,227,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-0.982,-2.609,1.627,,0.272,,B,0.47,-0.29,1.37,,74.48,OHH,-1.595,0.0495842,0.00226019,1.02006 beta-lactamase_625_E108W,beta-lactamase_625_108,TEM-1,beta-lactamase_625,P62593,1.02006,NO,108,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.46,-5.465,4.005,,0.572,G,A,1.04,1.87,20.151,20.151,72.73,PAB,-1.437,0.213352,0.00413372,1.02006 beta-lactamase_E166Y,beta-lactamase_166,TEM-1,beta-lactamase,P62593,1.02007,NO,166,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.756,-4.36,2.604,5.60527,0.508,G,A,0.52,1.05,2.124,,73.08,OAH,-1.42233,0.221079,0.00512989,1.02007 kka2_1:8_P45C,kka2_1:8_45,Kka2,kka2_1:8,P00552,1.02007,NO,45,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.774,-5.158,3.384,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.100394,0.00590481,1.02007 kka2_1:8_P45C,kka2_1:8_45,Kka2,kka2_1:8,P00552,1.02007,NO,45,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.774,-5.158,3.384,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.100394,0.00590481,1.02007 beta-lactamase_39_L219K,beta-lactamase_39_219,TEM-1,beta-lactamase_39,P62593,1.02011,NO,219,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.313,-3.875,2.562,,,I,A,0.55,-0.51,19.842,19.842,74.48,HHB,-1.21533,0.0495842,0.00664345,1.02011 beta-lactamase_39_K190L,beta-lactamase_39_190,TEM-1,beta-lactamase_39,P62593,1.02012,NO,190,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.994,-3.527,1.533,,0.371,H,A,2.34,0.16,1.513,,77.62,BBH,-1.64167,0.0495842,0.00574527,1.02012 beta-lactamase_39_R118A,beta-lactamase_39_118,TEM-1,beta-lactamase_39,P62593,1.02012,NO,118,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.413,-1.798,-0.615,,0.457,H,A,1.2,1.39,3.961,,77.62,HBA,-1.785,0.0495842,0.00538794,1.02012 beta-lactamase_N152Y,beta-lactamase_152,TEM-1,beta-lactamase,P62593,1.02012,NO,152,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-2.757,-4.312,1.555,5.98571,0.863,H,A,0.09,0.92,2.061,,77.62,BPH,-2.97,0.221079,0.00471429,1.02012 beta-lactamase_156_M127K,beta-lactamase_156_127,TEM-1,beta-lactamase_156,P62593,1.02014,NO,127,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-2.251,-3,0.749,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.111618,0.00437927,1.02014 beta-lactamase_625_Q97A,beta-lactamase_625_97,TEM-1,beta-lactamase_625,P62593,1.02014,NO,97,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.072,-2.26,0.188,,0.823,G,A,0.64,2.42,16.954,16.954,77.62,PPP,-2.43833,0.213352,0.0045116,1.02014 beta-lactamase_625_R202E,beta-lactamase_625_202,TEM-1,beta-lactamase_625,P62593,1.02014,NO,202,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.292,-3.173,1.881,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.213352,0.00321899,1.02014 WW_domain_D170C,WW_domain_170,Yap65,WW_domain,P46937,1.02014,NO,170,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.213,-4.987,3.774,,,,,,,0.399,,15.87,OAH,-1.38,0.153962,0.00123319,1.02014 beta-lactamase_0_Y44C,beta-lactamase_0_44,TEM-1,beta-lactamase_0,P62593,1.02016,NO,44,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-2.547,-4.829,2.282,,,E,B,0.21,-0.45,1.751,,73.78,OHH,-1.86267,0.0500837,0.00426364,1.02016 beta-lactamase_156_F228S,beta-lactamase_156_228,TEM-1,beta-lactamase_156,P62593,1.02016,NO,228,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-2.342,-3.492,1.15,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.111618,0.0046669,1.02016 beta-lactamase_2500_R118W,beta-lactamase_2500_118,TEM-1,beta-lactamase_2500,P62593,1.02017,NO,118,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.413,-5.439,3.026,,0.457,H,A,1.2,1.39,2.144,,77.62,HBA,-1.785,0.361275,0.00538794,1.02017 beta-lactamase_39_Q88Y,beta-lactamase_39_88,TEM-1,beta-lactamase_39,P62593,1.02019,NO,88,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.086,-4.349,2.263,,0.807,,B,0.64,2.03,11.108,11.108,77.62,APH,-1.53433,0.0495842,0.00504167,1.02019 beta-lactamase_625_T193H,beta-lactamase_625_193,TEM-1,beta-lactamase_625,P62593,1.02019,NO,193,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.914,-4.78,2.866,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.213352,0.00482669,1.02019 beta-lactamase_2500_H151Q,beta-lactamase_2500_151,TEM-1,beta-lactamase_2500,P62593,1.0202,NO,151,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-2.96,-2.497,-0.463,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.361275,0.00216946,1.0202 beta-lactamase_39_S80D,beta-lactamase_39_80,TEM-1,beta-lactamase_39,P62593,1.0202,NO,80,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.029,-2.7,0.671,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.0495842,0.00565569,1.0202 PSD95pdz3_F340Y,PSD95pdz3_340,PSD95pdz3,PSD95pdz3,P31016,1.02021,NO,340,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.524,-2.719,1.195,5.79283,,,,,11.8045,,,,PHH,-1.55767,0.0758425,0.000836987,1.02021 beta-lactamase_625_E238F,beta-lactamase_625_238,TEM-1,beta-lactamase_625,P62593,1.02022,NO,238,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.213352,0.00743256,1.02022 Pab1_I157C,Pab1_157,Pab1,Pab1,P04147,1.02022,NO,157,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.623,-4.526,2.903,,,,,,,1.439,,79.72,BHH,-1.28667,0.175299,0.0018103,1.02022 beta-lactamase_E166W,beta-lactamase_166,TEM-1,beta-lactamase,P62593,1.02023,NO,166,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.756,-5.495,3.739,5.60527,0.508,G,A,0.52,1.05,2.124,,73.08,OAH,-1.42233,0.221079,0.00512989,1.02023 gb1_T270H,gb1_270,gb1,gb1,P06654,1.02023,NO,270,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-3.15,-2.505,-0.645,,,,,,,1.326,,45.54,HPH,-1.843,0.177985,0.00223707,1.02023 beta-lactamase_39_A235M,beta-lactamase_39_235,TEM-1,beta-lactamase_39,P62593,1.02024,NO,235,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.266,-4.612,3.346,,0.32,E,B,0.46,-0.86,1.344,,50,OHO,-0.89,0.0495842,0.00493474,1.02024 beta-lactamase_39_T69S,beta-lactamase_39_69,TEM-1,beta-lactamase_39,P62593,1.02024,NO,69,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-0.973,-2.405,1.432,,,G,A,0.22,-1.24,4.194,,93.01,PPH,-1.01833,0.0495842,0.00127498,1.02024 beta-lactamase_39_L135Q,beta-lactamase_39_135,TEM-1,beta-lactamase_39,P62593,1.02025,NO,135,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.002,-4.162,3.16,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.0495842,0.00244423,1.02025 beta-lactamase_625_P255M,beta-lactamase_625_255,TEM-1,beta-lactamase_625,P62593,1.02025,NO,255,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.213352,0.00499612,1.02025 kka2_1:1_Q4V,kka2_1:1_4,Kka2,kka2_1:1,P00552,1.02025,NO,4,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.361,-3.536,1.175,,,,,,,5.615,,71.59,APA,-1.95533,0.520039,0.00239179,1.02025 kka2_1:8_L103T,kka2_1:8_103,Kka2,kka2_1:8,P00552,1.02026,NO,103,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-2.362,-2.414,0.052,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.100394,0.00574792,1.02026 kka2_1:8_L103T,kka2_1:8_103,Kka2,kka2_1:8,P00552,1.02026,NO,103,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-2.362,-2.414,0.052,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.100394,0.00574792,1.02026 beta-lactamase_156_L192M,beta-lactamase_156_192,TEM-1,beta-lactamase_156,P62593,1.02027,NO,192,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.254,-4.084,2.83,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.111618,0.00558728,1.02027 beta-lactamase_156_R239Q,beta-lactamase_156_239,TEM-1,beta-lactamase_156,P62593,1.02027,NO,239,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.111618,0.00213852,1.02027 beta-lactamase_625_E210N,beta-lactamase_625_210,TEM-1,beta-lactamase_625,P62593,1.02027,NO,210,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.319,-3.904,1.585,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.213352,0.00663582,1.02027 beta-lactamase_156_R273L,beta-lactamase_156_273,TEM-1,beta-lactamase_156,P62593,1.02028,NO,273,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.314,-3.556,1.242,,0.564,H,A,1.2,1.57,20.248,20.248,73.78,ABP,-1.841,0.111618,0.0077952,1.02028 beta-lactamase_156_I285G,beta-lactamase_156_285,TEM-1,beta-lactamase_156,P62593,1.02029,NO,285,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.111618,0.101555,1.02029 beta-lactamase_H24V,beta-lactamase_24,TEM-1,beta-lactamase,P62593,1.02029,NO,24,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-2.481,-3.524,1.043,5.82767,,,,,,2.708,,93.01,HBO,-1.85167,0.221079,0.00238894,1.02029 beta-lactamase_P20D,beta-lactamase_20,TEM-1,beta-lactamase,P62593,1.02029,NO,20,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.74,-3.664,1.924,,,,,,,0.368,,67.83,HOH,-1.765,0.221079,0.00235322,1.02029 beta-lactamase_2500_K32R,beta-lactamase_2500_32,TEM-1,beta-lactamase_2500,P62593,1.0203,NO,32,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.984,-2.38,0.396,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.361275,0.00401283,1.0203 beta-lactamase_39_M67A,beta-lactamase_39_67,TEM-1,beta-lactamase_39,P62593,1.0203,NO,67,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-2.231,-2.183,-0.048,,0.006,G,P,0.55,-0.81,1.463,,65.03,HHP,-1.502,0.0495842,0.00409753,1.0203 beta-lactamase_0_H156R,beta-lactamase_0_156,TEM-1,beta-lactamase_0,P62593,1.02031,NO,156,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-3.156,-2.742,-0.414,,0.753,S,A,0.17,-0.6,23.367,23.367,77.62,ABH,-1.932,0.0500837,0.00468596,1.02031 beta-lactamase_625_I285V,beta-lactamase_625_285,TEM-1,beta-lactamase_625,P62593,1.02032,NO,285,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.213352,0.101555,1.02032 beta-lactamase_156_M67T,beta-lactamase_156_67,TEM-1,beta-lactamase_156,P62593,1.02033,NO,67,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-2.231,-3.488,1.257,,0.006,G,P,0.55,-0.81,1.463,,65.03,HHP,-1.502,0.111618,0.00409753,1.02033 beta-lactamase_39_T147E,beta-lactamase_39_147,TEM-1,beta-lactamase_39,P62593,1.02034,NO,147,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.149,-3.519,2.37,,0.281,H,A,0.22,-0.68,13.843,13.843,64.34,HPH,-1.456,0.0495842,0.00226017,1.02034 E1_Ubiquitin_K48C,E1_Ubiquitin_48,Uba1,E1_Ubiquitin,P0CG63,1.02034,NO,48,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.219,-5.008,3.789,,0.132,E,B,,-0.28,,,,OBO,-1.109,0.18783,0.00100363,1.02034 E1_Ubiquitin_L71G,E1_Ubiquitin_71,Uba1,E1_Ubiquitin,P0CG63,1.02034,NO,71,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.039,-3.625,2.586,,0.591,E,B,,-0.69,,,,BHB,-1.19433,0.18783,0.00148349,1.02034 E1_Ubiquitin_L71M,E1_Ubiquitin_71,Uba1,E1_Ubiquitin,P0CG63,1.02034,NO,71,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.039,-3.622,2.583,,0.591,E,B,,-0.69,,,,BHB,-1.19433,0.18783,0.00148349,1.02034 E1_Ubiquitin_L71Y,E1_Ubiquitin_71,Uba1,E1_Ubiquitin,P0CG63,1.02034,NO,71,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.039,-3.755,2.716,,0.591,E,B,,-0.69,,,,BHB,-1.19433,0.18783,0.00148349,1.02034 beta-lactamase_2500_T112G,beta-lactamase_2500_112,TEM-1,beta-lactamase_2500,P62593,1.02035,NO,112,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.186,-1.822,-0.364,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.361275,0.00531334,1.02035 kka2_1:2_R239A,kka2_1:2_239,Kka2,kka2_1:2,P00552,1.02036,NO,239,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.949,-2.185,-0.764,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.295029,0.00835326,1.02036 PSD95pdz3_E331D,PSD95pdz3_331,PSD95pdz3,PSD95pdz3,P31016,1.02037,NO,331,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.404,-2.475,1.071,5.86289,,,,,51.8889,,,,OAA,-1.22533,0.0758425,0.000950134,1.02037 PSD95pdz3_T385N,PSD95pdz3_385,PSD95pdz3,PSD95pdz3,P31016,1.02037,NO,385,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.533,-3.129,1.596,5.57157,,,,,23.6871,4.527,,87.71,PPH,-1.56567,0.0758425,0.000545119,1.02037 kka2_1:8_T125V,kka2_1:8_125,Kka2,kka2_1:8,P00552,1.0204,NO,125,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.622,-2.85,0.228,,0.791,T,A,0.22,0.33,2.675,,92.05,BPH,-1.56933,0.100394,0.00821755,1.0204 kka2_1:8_T125V,kka2_1:8_125,Kka2,kka2_1:8,P00552,1.0204,NO,125,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.622,-2.85,0.228,,0.791,T,A,0.22,0.33,2.675,,92.05,BPH,-1.56933,0.100394,0.00821755,1.0204 kka2_1:8_H8L,kka2_1:8_8,Kka2,kka2_1:8,P00552,1.02041,NO,8,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-2.759,-3.165,0.406,,,,,,,,,71.59,HBH,-2.25467,0.100394,0.00256422,1.02041 kka2_1:8_H8L,kka2_1:8_8,Kka2,kka2_1:8,P00552,1.02041,NO,8,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-2.759,-3.165,0.406,,,,,,,,,71.59,HBH,-2.25467,0.100394,0.00256422,1.02041 beta-lactamase_39_L38T,beta-lactamase_39_38,TEM-1,beta-lactamase_39,P62593,1.02042,NO,38,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.343,-3.495,2.152,,0.088,H,A,0.55,0.2,17.089,17.089,64.34,PHO,-1.78033,0.0495842,0.00373244,1.02042 beta-lactamase_625_E210D,beta-lactamase_625_210,TEM-1,beta-lactamase_625,P62593,1.02042,NO,210,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.319,-3.702,1.383,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.213352,0.00663582,1.02042 beta-lactamase_156_I45F,beta-lactamase_156_45,TEM-1,beta-lactamase_156,P62593,1.02044,NO,45,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-2.421,-3.147,0.726,,,E,B,0.48,-0.3,2.256,,77.62,HHA,-2.30267,0.111618,0.00452842,1.02044 beta-lactamase_39_V78E,beta-lactamase_39_78,TEM-1,beta-lactamase_39,P62593,1.02044,NO,78,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.459,-3.911,2.452,,,H,A,0.44,-0.47,1.132,,63.64,HHH,-1.17833,0.0495842,0.00492501,1.02044 beta-lactamase_156_I280V,beta-lactamase_156_280,TEM-1,beta-lactamase_156,P62593,1.02045,NO,280,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.111618,0.0530888,1.02045 beta-lactamase_156_A211R,beta-lactamase_156_211,TEM-1,beta-lactamase_156,P62593,1.02046,NO,211,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.896,-3.077,1.181,,0.369,T,A,0.46,-0.69,8.527,8.527,77.62,AHA,-1.94633,0.111618,0.00648183,1.02046 beta-lactamase_39_V78C,beta-lactamase_39_78,TEM-1,beta-lactamase_39,P62593,1.02046,NO,78,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.459,-4.812,3.353,,,H,A,0.44,-0.47,1.132,,63.64,HHH,-1.17833,0.0495842,0.00492501,1.02046 beta-lactamase_156_M67F,beta-lactamase_156_67,TEM-1,beta-lactamase_156,P62593,1.02047,NO,67,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-2.231,-4.128,1.897,,0.006,G,P,0.55,-0.81,1.463,,65.03,HHP,-1.502,0.111618,0.00409753,1.02047 beta-lactamase_39_E166M,beta-lactamase_39_166,TEM-1,beta-lactamase_39,P62593,1.02048,NO,166,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.756,-4.707,2.951,,0.508,G,A,1.04,1.05,17.227,17.227,73.08,OAH,-1.42233,0.0495842,0.00512989,1.02048 beta-lactamase_625_V29A,beta-lactamase_625_29,TEM-1,beta-lactamase_625,P62593,1.02048,NO,29,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-2.856,-2.61,-0.246,,0.733,H,A,0.44,-0.78,1.931,,93.01,HHB,-2.24733,0.213352,0.00318969,1.02048 beta-lactamase_0_H110F,beta-lactamase_0_110,TEM-1,beta-lactamase_0,P62593,1.02049,NO,110,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-1.706,-4.019,2.313,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.0500837,0.00441499,1.02049 beta-lactamase_T139A,beta-lactamase_139,TEM-1,beta-lactamase,P62593,1.02049,NO,139,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.901,-2.031,0.13,5.69095,0.216,H,A,0.3,0.39,2.256,,77.62,PPH,-2.04667,0.221079,0.00441837,1.02049 beta-lactamase_39_T112V,beta-lactamase_39_112,TEM-1,beta-lactamase_39,P62593,1.0205,NO,112,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.186,-2.929,0.743,,0.921,T,A,0.22,1.06,2.87,,73.78,HPA,-1.925,0.0495842,0.00531334,1.0205 beta-lactamase_0_S283F,beta-lactamase_0_283,TEM-1,beta-lactamase_0,P62593,1.02052,NO,283,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.0500837,0.0429138,1.02052 PSD95pdz3_V365Q,PSD95pdz3_365,PSD95pdz3,PSD95pdz3,P31016,1.02052,NO,365,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.592,-3.805,2.213,5.03791,,,,,18.9657,2.364,,81.35,OHA,-1.288,0.0758425,0.000649764,1.02052 beta-lactamase_E61H,beta-lactamase_61,TEM-1,beta-lactamase,P62593,1.02053,NO,61,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.115,-4.518,2.403,6.29701,0.775,T,a,0.52,1.29,1.975,,77.62,OAA,-1.92567,0.221079,0.00440955,1.02053 beta-lactamase_I171L,beta-lactamase_171,TEM-1,beta-lactamase,P62593,1.02053,NO,171,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-2.431,-1.98,-0.451,5.22771,0.361,,B,1,0.53,1.66,,77.62,HHO,-1.55533,0.221079,0.00623355,1.02053 beta-lactamase_M67A,beta-lactamase_67,TEM-1,beta-lactamase,P62593,1.02053,NO,67,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-2.231,-2.183,-0.048,4.9618,0.006,G,P,1.07,-0.81,1.463,,65.03,HHP,-1.502,0.221079,0.00409753,1.02053 beta-lactamase_156_L89W,beta-lactamase_156_89,TEM-1,beta-lactamase_156,P62593,1.02055,NO,89,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.096,-5.236,4.14,,0.168,T,A,0.55,0.63,2.633,,64.34,PHO,-1.75767,0.111618,0.00207068,1.02055 Pab1_T159Y,Pab1_159,Pab1,Pab1,P04147,1.02055,NO,159,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.445,-4.071,2.626,,,,,,,2.531,,79.03,HPA,-1.19467,0.175299,0.00133849,1.02055 PSD95pdz3_Q358S,PSD95pdz3_358,PSD95pdz3,PSD95pdz3,P31016,1.02055,NO,358,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-1.699,-2.842,1.143,5.21282,,,,,14.8844,,,,APH,-1.531,0.0758425,0.000594893,1.02055 PSD95pdz3_G351N,PSD95pdz3_351,PSD95pdz3,PSD95pdz3,P31016,1.02056,NO,351,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.008,-3.13,2.122,5.44798,,,,,20.7625,,,,POA,-1.37133,0.0758425,0.000691282,1.02056 beta-lactamase_39_A282S,beta-lactamase_39_282,TEM-1,beta-lactamase_39,P62593,1.02058,NO,282,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.0495842,0.0449821,1.02058 beta-lactamase_39_Q276N,beta-lactamase_39_276,TEM-1,beta-lactamase_39,P62593,1.02058,NO,276,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.0495842,0.0191712,1.02058 beta-lactamase_156_E61Q,beta-lactamase_156_61,TEM-1,beta-lactamase_156,P62593,1.02059,NO,61,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.115,-2.702,0.587,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.111618,0.00440955,1.02059 Pab1_I196L,Pab1_196,Pab1,Pab1,P04147,1.02059,NO,196,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.795,-2.497,0.702,,,,,,,2.013,,80.59,AHH,-1.44667,0.175299,0.0016933,1.02059 WW_domain_D194D,WW_domain_194,Yap65,WW_domain,P46937,1.02059,NO,194,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.536,-1.536,0,5.95614,,,,,,1.948,,74.4,HAP,-1.78933,0.153962,0.00483742,1.02059 beta-lactamase_2500_L28K,beta-lactamase_2500_28,TEM-1,beta-lactamase_2500,P62593,1.0206,NO,28,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.579,-3.608,2.029,,0.277,H,A,0.55,-0.16,2.716,,93.01,PHH,-2.11333,0.361275,0.00359321,1.0206 beta-lactamase_625_M270I,beta-lactamase_625_270,TEM-1,beta-lactamase_625,P62593,1.0206,NO,270,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.213352,0.00767762,1.0206 Pab1_Q194H,Pab1_194,Pab1,Pab1,P04147,1.02061,NO,194,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.179,-2.493,0.314,,,,,,,,,,OPA,-1.59767,0.175299,0.0016145,1.02061 beta-lactamase_T186L,beta-lactamase_186,TEM-1,beta-lactamase,P62593,1.02062,NO,186,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.522,-2.882,0.36,5.07364,0.396,H,A,0.3,-0.28,2.144,,77.62,HPP,-1.77633,0.221079,0.00485034,1.02062 beta-lactamase_156_E238C,beta-lactamase_156_238,TEM-1,beta-lactamase_156,P62593,1.02063,NO,238,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.111618,0.00743256,1.02063 beta-lactamase_39_P143Y,beta-lactamase_39_143,TEM-1,beta-lactamase_39,P62593,1.02063,NO,143,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.967,-4.337,3.37,,0.075,H,A,0.52,-0.37,0.976,,66.78,OOB,-1.354,0.0495842,0.00114551,1.02063 beta-lactamase_39_L188M,beta-lactamase_39_188,TEM-1,beta-lactamase_39,P62593,1.02064,NO,188,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.166,-2.706,1.54,,,H,A,0.55,-0.3,2.982,,60.14,PHB,-1.47033,0.0495842,0.00295687,1.02064 beta-lactamase_39_I54H,beta-lactamase_39_54,TEM-1,beta-lactamase_39,P62593,1.02065,NO,54,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-2.838,-3.42,0.582,,0.669,E,B,0.48,-0.14,1.349,,73.78,BHH,-2.337,0.0495842,0.00403589,1.02065 Pab1_S165N,Pab1_165,Pab1,Pab1,P04147,1.02066,NO,165,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.146,-3.04,1.894,,0.12,,a,,0.11,,,,BPB,-1.56867,0.175299,0.000307838,1.02066 beta-lactamase_156_V29D,beta-lactamase_156_29,TEM-1,beta-lactamase_156,P62593,1.02067,NO,29,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-2.856,-2.298,-0.558,,0.733,H,A,0.44,-0.78,3.685,,93.01,HHB,-2.24733,0.111618,0.00318969,1.02067 beta-lactamase_39_I244M,beta-lactamase_39_244,TEM-1,beta-lactamase_39,P62593,1.02067,NO,244,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.555,-4.138,2.583,,,E,B,0.48,-0.84,1.325,,77.62,OHH,-1.385,0.0495842,0.00605379,1.02067 beta-lactamase_M180T,beta-lactamase_180,TEM-1,beta-lactamase,P62593,1.02067,NO,180,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-2.795,-1.278,-1.517,4.96809,0.242,,B,1.07,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.221079,0.00552048,1.02067 beta-lactamase_0_S283G,beta-lactamase_0_283,TEM-1,beta-lactamase_0,P62593,1.02068,NO,283,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.0500837,0.0429138,1.02068 beta-lactamase_156_E102K,beta-lactamase_156_102,TEM-1,beta-lactamase_156,P62593,1.02068,NO,102,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.118,-2.64,0.522,,0.722,S,B,1.04,1.82,15.721,15.721,73.08,HAH,-1.581,0.111618,0.00486633,1.02068 beta-lactamase_0_T187G,beta-lactamase_0_187,TEM-1,beta-lactamase_0,P62593,1.02071,NO,187,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.401,-3.394,1.993,,0.007,H,A,0.22,-1.19,3.259,,67.48,PPH,-1.69633,0.0500837,0.00491782,1.02071 beta-lactamase_156_P224M,beta-lactamase_156_224,TEM-1,beta-lactamase_156,P62593,1.02071,NO,224,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.893,-4.704,3.811,,0.383,,B,0.52,-0.3,0.383,,74.48,HOH,-1.26433,0.111618,0.00189564,1.02071 beta-lactamase_2500_T186R,beta-lactamase_2500_186,TEM-1,beta-lactamase_2500,P62593,1.02071,NO,186,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.522,-2.819,0.297,,0.396,H,A,0.22,-0.28,2.144,,77.62,HPP,-1.77633,0.361275,0.00485034,1.02071 beta-lactamase_39_I258V,beta-lactamase_39_258,TEM-1,beta-lactamase_39,P62593,1.02071,NO,258,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.975,-2.547,0.572,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.0495842,0.007931,1.02071 beta-lactamase_39_K190E,beta-lactamase_39_190,TEM-1,beta-lactamase_39,P62593,1.02071,NO,190,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.994,-3.44,1.446,,0.371,H,A,2.34,0.16,1.513,,77.62,BBH,-1.64167,0.0495842,0.00574527,1.02071 beta-lactamase_156_F58W,beta-lactamase_156_58,TEM-1,beta-lactamase_156,P62593,1.02072,NO,58,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-2.914,-2.275,-0.639,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.111618,0.00523369,1.02072 beta-lactamase_A280K,beta-lactamase_280,TEM-1,beta-lactamase,P62593,1.02073,NO,280,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.708,-2.289,0.581,4.74932,0.379,H,A,0.52,-0.72,1.785,,68.18,OHP,-1.66433,0.221079,0.0530888,1.02073 beta-lactamase_I171V,beta-lactamase_171,TEM-1,beta-lactamase,P62593,1.02073,NO,171,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-2.431,-3.274,0.843,5.22771,0.361,,B,1,0.53,1.66,,77.62,HHO,-1.55533,0.221079,0.00623355,1.02073 beta-lactamase_S281V,beta-lactamase_281,TEM-1,beta-lactamase,P62593,1.02073,NO,281,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.247,-2.57,0.323,4.73591,0.128,H,A,0.25,-0.26,2.144,,77.62,HPH,-1.847,0.221079,0.0406482,1.02073 beta-lactamase_156_V78I,beta-lactamase_156_78,TEM-1,beta-lactamase_156,P62593,1.02074,NO,78,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.459,-1.96,0.501,,,H,A,0.44,-0.47,1.132,,63.64,HHH,-1.17833,0.111618,0.00492501,1.02074 beta-lactamase_39_N274A,beta-lactamase_39_274,TEM-1,beta-lactamase_39,P62593,1.02074,NO,274,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.0495842,0.0110418,1.02074 beta-lactamase_625_N50H,beta-lactamase_625_50,TEM-1,beta-lactamase_625,P62593,1.02075,NO,50,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-2.979,-3.33,0.351,,0.912,T,A,0.61,1.24,3.446,,77.62,HPP,-2.134,0.213352,0.0047211,1.02075 beta-lactamase_625_Q97S,beta-lactamase_625_97,TEM-1,beta-lactamase_625,P62593,1.02075,NO,97,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.072,-3.388,1.316,,0.823,G,A,0.64,2.42,16.954,16.954,77.62,PPP,-2.43833,0.213352,0.0045116,1.02075 beta-lactamase_156_V106Y,beta-lactamase_156_106,TEM-1,beta-lactamase_156,P62593,1.02077,NO,106,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.218,-3.895,2.677,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.111618,0.00304168,1.02077 kka2_1:4_L103V,kka2_1:4_103,Kka2,kka2_1:4,P00552,1.02078,NO,103,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-2.362,-2.108,-0.254,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.168804,0.00574792,1.02078 beta-lactamase_156_G281F,beta-lactamase_156_281,TEM-1,beta-lactamase_156,P62593,1.02079,NO,281,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.111618,0.0406482,1.02079 beta-lactamase_39_N173A,beta-lactamase_39_173,TEM-1,beta-lactamase_39,P62593,1.02079,NO,173,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-2.663,-2.432,-0.231,,1.044,T,l,0.61,1.25,1.426,,77.62,OPA,-1.46633,0.0495842,0.0033769,1.02079 beta-lactamase_156_E87L,beta-lactamase_156_87,TEM-1,beta-lactamase_156,P62593,1.0208,NO,87,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.421,-2.529,1.108,,0.048,,B,1.04,0.92,1.754,,64.69,PAP,-1.969,0.111618,0.00337888,1.0208 beta-lactamase_625_I277V,beta-lactamase_625_277,TEM-1,beta-lactamase_625,P62593,1.0208,NO,277,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.213352,0.0169305,1.0208 Pab1_D136L,Pab1_136,Pab1,Pab1,P04147,1.0208,NO,136,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.602,-3.195,1.593,,,,,,,,,,OAH,-1.42367,0.175299,0.00227029,1.0208 PSD95pdz3_G344D,PSD95pdz3_344,PSD95pdz3,PSD95pdz3,P31016,1.02082,NO,344,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.008,-3.15,2.142,4.83855,,,,,14.06,,,,HOO,-1.10767,0.0758425,0.00078498,1.02082 beta-lactamase_D33D,beta-lactamase_33,TEM-1,beta-lactamase,P62593,1.02083,NO,33,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.321,-2.321,,5.05203,0.366,H,A,0.23,0.33,2.032,,77.62,BAH,-2.12133,0.221079,0.00435556,1.02083 beta-lactamase_156_I171Q,beta-lactamase_156_171,TEM-1,beta-lactamase_156,P62593,1.02084,NO,171,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-2.431,-3.168,0.737,,0.361,,B,0.48,0.53,3.869,,77.62,HHO,-1.55533,0.111618,0.00623355,1.02084 beta-lactamase_0_Y95F,beta-lactamase_0_95,TEM-1,beta-lactamase_0,P62593,1.02085,NO,95,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-1.715,-2.096,0.381,,0.122,,b,0.21,-0.37,2.914,,77.62,BHP,-2.16167,0.0500837,0.00479449,1.02085 beta-lactamase_156_F228R,beta-lactamase_156_228,TEM-1,beta-lactamase_156,P62593,1.02085,NO,228,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-2.342,-2.044,-0.298,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.111618,0.0046669,1.02085 beta-lactamase_625_H110E,beta-lactamase_625_110,TEM-1,beta-lactamase_625,P62593,1.02085,NO,110,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-1.706,-2.766,1.06,,0.341,G,a,0.17,1.08,31.31,31.31,64.69,BBH,-1.73333,0.213352,0.00441499,1.02085 beta-lactamase_625_H151N,beta-lactamase_625_151,TEM-1,beta-lactamase_625,P62593,1.02085,NO,151,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-2.96,-3.49,0.53,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.213352,0.00216946,1.02085 kka2_1:4_A78C,kka2_1:4_78,Kka2,kka2_1:4,P00552,1.02086,NO,78,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.744,-4.918,3.174,,0.078,.,B,0.46,-0.53,0.594,,56.06,OHH,-1.863,0.168804,0.00457299,1.02086 beta-lactamase_2500_E210R,beta-lactamase_2500_210,TEM-1,beta-lactamase_2500,P62593,1.02087,NO,210,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.319,-3.045,0.726,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.361275,0.00663582,1.02087 beta-lactamase_39_P250T,beta-lactamase_39_250,TEM-1,beta-lactamase_39,P62593,1.02087,NO,250,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.0495842,0.00550899,1.02087 beta-lactamase_625_A200C,beta-lactamase_625_200,TEM-1,beta-lactamase_625,P62593,1.02087,NO,200,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.878,-5.005,3.127,,0.757,H,A,0.46,-0.19,12.672,12.672,77.62,HHP,-2.001,0.213352,0.0060056,1.02087 beta-lactamase_G251N,beta-lactamase_251,TEM-1,beta-lactamase,P62593,1.02088,NO,251,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.907,-2.439,0.532,5.33865,0.506,T,l,0.73,0.17,10.663,,65.38,AOB,-2.06067,0.221079,0.00733416,1.02088 beta-lactamase_N173L,beta-lactamase_173,TEM-1,beta-lactamase,P62593,1.02088,NO,173,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-2.663,-3.749,1.086,7.02497,1.044,T,l,0.09,1.25,1.88,,77.62,OPA,-1.46633,0.221079,0.0033769,1.02088 PSD95pdz3_T387M,PSD95pdz3_387,PSD95pdz3,PSD95pdz3,P31016,1.02088,NO,387,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.391,-4.162,2.771,5.20757,,,,,18.8043,,,,HPH,-1.49533,0.0758425,0.000167911,1.02088 beta-lactamase_625_E87L,beta-lactamase_625_87,TEM-1,beta-lactamase_625,P62593,1.02089,NO,87,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.421,-2.529,1.108,,0.048,,B,1.04,0.92,17.923,17.923,64.69,PAP,-1.969,0.213352,0.00337888,1.02089 beta-lactamase_156_L192T,beta-lactamase_156_192,TEM-1,beta-lactamase_156,P62593,1.02091,NO,192,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.254,-3.48,2.226,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.111618,0.00558728,1.02091 PSD95pdz3_Q358Y,PSD95pdz3_358,PSD95pdz3,PSD95pdz3,P31016,1.02091,NO,358,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-1.699,-3.619,1.92,5.21282,,,,,14.8844,,,,APH,-1.531,0.0758425,0.000594893,1.02091 beta-lactamase_625_V260I,beta-lactamase_625_260,TEM-1,beta-lactamase_625,P62593,1.02092,NO,260,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.213352,0.00471757,1.02092 kka2_1:2_A248S,kka2_1:2_248,Kka2,kka2_1:2,P00552,1.02093,NO,248,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.124,-2.844,0.72,,0.825,S,b,0.46,0.46,,,92.05,HHO,-2.15,0.295029,0.0125484,1.02093 gb1_T244K,gb1_244,gb1,gb1,P06654,1.02094,NO,244,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.637,-3.374,1.737,,,,,,,0.202,,11.83,PPA,-1.92567,0.177985,0.00222755,1.02094 beta-lactamase_156_D36K,beta-lactamase_156_36,TEM-1,beta-lactamase_156,P62593,1.02095,NO,36,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.732,-2.543,-0.189,,0.555,H,A,0.75,1.17,14.871,14.871,77.62,AAP,-1.91167,0.111618,0.00476483,1.02095 beta-lactamase_156_S57F,beta-lactamase_156_57,TEM-1,beta-lactamase_156,P62593,1.02095,NO,57,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.918,-4.274,2.356,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.111618,0.00492804,1.02095 beta-lactamase_156_T112G,beta-lactamase_156_112,TEM-1,beta-lactamase_156,P62593,1.02096,NO,112,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.186,-1.822,-0.364,,0.921,T,A,0.22,1.06,2.87,,73.78,HPA,-1.925,0.111618,0.00531334,1.02096 beta-lactamase_39_K30T,beta-lactamase_39_30,TEM-1,beta-lactamase_39,P62593,1.02096,NO,30,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-2.307,-2.199,-0.108,,0.142,H,A,2.34,-0.65,6.717,,93.01,HBH,-2.32833,0.0495842,0.00448593,1.02096 beta-lactamase_625_A34F,beta-lactamase_625_34,TEM-1,beta-lactamase_625,P62593,1.02097,NO,34,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.059,-3.937,1.878,,,H,A,0.46,-0.54,3.614,,73.78,AHA,-1.74967,0.213352,0.00407913,1.02097 beta-lactamase_625_E46S,beta-lactamase_625_46,TEM-1,beta-lactamase_625,P62593,1.02097,NO,46,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.94,-3.545,1.605,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.213352,0.00427568,1.02097 beta-lactamase_625_E26W,beta-lactamase_625_26,TEM-1,beta-lactamase_625,P62593,1.02098,NO,26,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.454,-5.402,2.948,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.213352,0.00297948,1.02098 beta-lactamase_2500_T186Q,beta-lactamase_2500_186,TEM-1,beta-lactamase_2500,P62593,1.02099,NO,186,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.522,-2.514,-0.008,,0.396,H,A,0.22,-0.28,2.144,,77.62,HPP,-1.77633,0.361275,0.00485034,1.02099 beta-lactamase_39_T269N,beta-lactamase_39_269,TEM-1,beta-lactamase_39,P62593,1.02099,NO,269,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.156,,,,0.646,H,A,0.53,0.4,3.889,,77.62,HPH,-1.96733,0.0495842,0.00950944,1.02099 kka2_1:8_A14D,kka2_1:8_14,Kka2,kka2_1:8,P00552,1.02099,NO,14,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.837,-2.812,0.975,,0.728,G,A,0.46,0.7,,,71.59,HHH,-1.82567,0.100394,0.00706614,1.02099 kka2_1:8_A14D,kka2_1:8_14,Kka2,kka2_1:8,P00552,1.02099,NO,14,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.837,-2.812,0.975,,0.728,G,A,0.46,0.7,,,71.59,HHH,-1.82567,0.100394,0.00706614,1.02099 PSD95pdz3_D332T,PSD95pdz3_332,PSD95pdz3,PSD95pdz3,P31016,1.02099,NO,332,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.264,-3.103,1.839,6.09878,,,,,48.762,,,,AAO,-1.22533,0.0758425,0.000937818,1.02099 beta-lactamase_39_R81I,beta-lactamase_39_81,TEM-1,beta-lactamase_39,P62593,1.021,NO,81,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.466,-4.004,2.538,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.0495842,0.00499763,1.021 beta-lactamase_0_G216I,beta-lactamase_0_216,TEM-1,beta-lactamase_0,P62593,1.02103,NO,216,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.477,-4.183,2.706,,0.437,I,A,0.29,-0.58,0.834,,74.48,HOO,-1.68067,0.0500837,0.00639568,1.02103 beta-lactamase_156_E210D,beta-lactamase_156_210,TEM-1,beta-lactamase_156,P62593,1.02104,NO,210,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.319,-3.702,1.383,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.111618,0.00663582,1.02104 beta-lactamase_39_E272T,beta-lactamase_39_272,TEM-1,beta-lactamase_39,P62593,1.02104,NO,272,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.127,,,,0.081,H,A,0.43,-0.97,12.983,12.983,63.64,AAB,-1.56333,0.0495842,0.00545371,1.02104 beta-lactamase_A280Q,beta-lactamase_280,TEM-1,beta-lactamase,P62593,1.02104,NO,280,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.708,-2.669,0.961,4.74932,0.379,H,A,0.52,-0.72,1.785,,68.18,OHP,-1.66433,0.221079,0.0530888,1.02104 beta-lactamase_D33Y,beta-lactamase_33,TEM-1,beta-lactamase,P62593,1.02104,NO,33,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.321,-4.331,2.01,5.05203,0.366,H,A,0.23,0.33,2.032,,77.62,BAH,-2.12133,0.221079,0.00435556,1.02104 beta-lactamase_H24T,beta-lactamase_24,TEM-1,beta-lactamase,P62593,1.02104,NO,24,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-2.481,-2.645,0.164,5.82767,,,,,,2.708,,93.01,HBO,-1.85167,0.221079,0.00238894,1.02104 beta-lactamase_K32K,beta-lactamase_32,TEM-1,beta-lactamase,P62593,1.02104,NO,32,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.984,-1.984,,5.55842,0.563,H,A,1.82,0.34,1.754,,73.08,HBA,-2.04233,0.221079,0.00401283,1.02104 beta-lactamase_N98E,beta-lactamase_98,TEM-1,beta-lactamase,P62593,1.02104,NO,98,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-2.973,-2.445,-0.528,6.59973,0.963,G,A,1.07,1.35,1.332,,77.62,PPA,-2.07867,0.221079,0.00505389,1.02104 beta-lactamase_R118S,beta-lactamase_118,TEM-1,beta-lactamase,P62593,1.02104,NO,118,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.413,-2.394,-0.019,5.8227,0.457,H,A,0.68,1.39,2.144,,77.62,HBA,-1.785,0.221079,0.00538794,1.02104 beta-lactamase_T112D,beta-lactamase_112,TEM-1,beta-lactamase,P62593,1.02104,NO,112,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.186,-2.66,0.474,6.47162,0.921,T,A,0.77,1.06,2.04,,73.78,HPA,-1.925,0.221079,0.00531334,1.02104 beta-lactamase_625_A222K,beta-lactamase_625_222,TEM-1,beta-lactamase_625,P62593,1.02105,NO,222,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.103,-3.694,1.591,,0.233,H,A,0.46,-0.25,1.448,,77.62,PHH,-1.63733,0.213352,0.00466094,1.02105 PSD95pdz3_T387Y,PSD95pdz3_387,PSD95pdz3,PSD95pdz3,P31016,1.02105,NO,387,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.391,-3.844,2.453,5.20757,,,,,18.8043,,,,HPH,-1.49533,0.0758425,0.000167911,1.02105 beta-lactamase_625_A182K,beta-lactamase_625_182,TEM-1,beta-lactamase_625,P62593,1.02108,NO,182,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.777,-2.859,1.082,,0.136,H,A,0.46,-0.66,16.784,16.784,93.01,OHH,-1.27367,0.213352,0.00559099,1.02108 beta-lactamase_2500_D36W,beta-lactamase_2500_36,TEM-1,beta-lactamase_2500,P62593,1.02109,NO,36,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.732,-5.422,2.69,,0.555,H,A,0.75,1.17,2.26,,77.62,AAP,-1.91167,0.361275,0.00476483,1.02109 beta-lactamase_39_L89H,beta-lactamase_39_89,TEM-1,beta-lactamase_39,P62593,1.02111,NO,89,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.096,-4.892,3.796,,0.168,T,A,0.55,0.63,3.233,,64.34,PHO,-1.75767,0.0495842,0.00207068,1.02111 beta-lactamase_39_H110L,beta-lactamase_39_110,TEM-1,beta-lactamase_39,P62593,1.02112,NO,110,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-1.706,-3.515,1.809,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.0495842,0.00441499,1.02112 beta-lactamase_156_S51D,beta-lactamase_156_51,TEM-1,beta-lactamase_156,P62593,1.02114,NO,51,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.526,-2.756,1.23,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.111618,0.00504821,1.02114 kka2_1:4_E142M,kka2_1:4_142,Kka2,kka2_1:4,P00552,1.02116,NO,142,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.221,-4.819,2.598,,0.471,H,A,1.52,0.85,3.693,,65.53,HAB,-2.08033,0.168804,0.00748883,1.02116 beta-lactamase_156_R118N,beta-lactamase_156_118,TEM-1,beta-lactamase_156,P62593,1.02118,NO,118,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.413,-3.711,1.298,,0.457,H,A,1.2,1.39,2.231,,77.62,HBA,-1.785,0.111618,0.00538794,1.02118 WW_domain_S183N,WW_domain_183,Yap65,WW_domain,P46937,1.02118,NO,183,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.95,-2.489,0.539,5.35576,,,,,,1.594,,83.93,PPP,-1.48733,0.153962,0.00445513,1.02118 beta-lactamase_2500_A182K,beta-lactamase_2500_182,TEM-1,beta-lactamase_2500,P62593,1.0212,NO,182,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.777,-2.859,1.082,,0.136,H,A,0.46,-0.66,2.032,,93.01,OHH,-1.27367,0.361275,0.00559099,1.0212 beta-lactamase_0_H24Q,beta-lactamase_0_24,TEM-1,beta-lactamase_0,P62593,1.02121,NO,24,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-2.481,-2.604,0.123,,,,,,,2.708,,93.01,OBO,-2.0035,0.0500837,0.00238894,1.02121 beta-lactamase_156_G114M,beta-lactamase_156_114,TEM-1,beta-lactamase_156,P62593,1.02121,NO,114,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.094,-4.83,3.736,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.111618,0.00224919,1.02121 Pab1_K164F,Pab1_164,Pab1,Pab1,P04147,1.02121,NO,164,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-2.298,-4.154,1.856,,,,,,,,,,OBP,-1.41767,0.175299,0.00255241,1.02121 PSD95pdz3_V365E,PSD95pdz3_365,PSD95pdz3,PSD95pdz3,P31016,1.02121,NO,365,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.592,-3.346,1.754,5.03791,,,,,18.9657,2.364,,81.35,OHA,-1.288,0.0758425,0.000649764,1.02121 beta-lactamase_0_R91T,beta-lactamase_0_91,TEM-1,beta-lactamase_0,P62593,1.02122,NO,91,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.392,-2.721,1.329,,0.444,,B,1.2,0.96,4.557,,50.35,OBB,-1.73367,0.0500837,0.00380226,1.02122 gb1_D262E,gb1_262,gb1,gb1,P06654,1.02123,NO,262,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-3.132,-1.897,-1.235,,,,,,,1.304,,45.54,PAP,-2.05233,0.177985,0.00413102,1.02123 gb1_I232E,gb1_232,gb1,gb1,P06654,1.02123,NO,232,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-2.175,-3.542,1.367,,,,,,,0.766,,44.87,HHH,-2.152,0.177985,0.00580459,1.02123 kka2_1:2_T125C,kka2_1:2_125,Kka2,kka2_1:2,P00552,1.02124,NO,125,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.622,-5.084,2.462,,0.791,T,A,0.22,0.33,2.029,,92.05,BPH,-1.56933,0.295029,0.00821755,1.02124 beta-lactamase_156_A211I,beta-lactamase_156_211,TEM-1,beta-lactamase_156,P62593,1.02125,NO,211,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.896,-4.033,2.137,,0.369,T,A,0.46,-0.69,8.527,8.527,77.62,AHA,-1.94633,0.111618,0.00648183,1.02125 beta-lactamase_2500_T269N,beta-lactamase_2500_269,TEM-1,beta-lactamase_2500,P62593,1.02126,NO,269,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.361275,0.00950944,1.02126 beta-lactamase_39_A235S,beta-lactamase_39_235,TEM-1,beta-lactamase_39,P62593,1.02126,NO,235,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.266,-2.058,0.792,,0.32,E,B,0.46,-0.86,1.344,,50,OHO,-0.89,0.0495842,0.00493474,1.02126 kka2_1:8_P132W,kka2_1:8_132,Kka2,kka2_1:8,P00552,1.02128,NO,132,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.775,-5.574,4.799,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.100394,0.0018489,1.02128 kka2_1:8_P132W,kka2_1:8_132,Kka2,kka2_1:8,P00552,1.02128,NO,132,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.775,-5.574,4.799,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.100394,0.0018489,1.02128 beta-lactamase_156_A182L,beta-lactamase_156_182,TEM-1,beta-lactamase_156,P62593,1.02129,NO,182,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.777,-3.486,1.709,,0.136,H,A,0.46,-0.66,16.784,16.784,93.01,OHH,-1.27367,0.111618,0.00559099,1.02129 beta-lactamase_39_R273M,beta-lactamase_39_273,TEM-1,beta-lactamase_39,P62593,1.0213,NO,273,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.314,-4.698,2.384,,0.564,H,A,1.2,1.57,2.163,,73.78,ABP,-1.841,0.0495842,0.0077952,1.0213 beta-lactamase_156_V106A,beta-lactamase_156_106,TEM-1,beta-lactamase_156,P62593,1.02131,NO,106,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.218,-3.084,1.866,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.111618,0.00304168,1.02131 beta-lactamase_39_T147M,beta-lactamase_39_147,TEM-1,beta-lactamase_39,P62593,1.02131,NO,147,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.149,-4.573,3.424,,0.281,H,A,0.22,-0.68,13.843,13.843,64.34,HPH,-1.456,0.0495842,0.00226017,1.02131 beta-lactamase_K144S,beta-lactamase_144,TEM-1,beta-lactamase,P62593,1.02132,NO,144,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-2.388,-2.51,0.122,6.02507,0.863,H,A,2.81,1.27,0.515,,77.62,OBA,-1.904,0.221079,0.00481141,1.02132 Pab1_N162M,Pab1_162,Pab1,Pab1,P04147,1.02133,NO,162,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-2.313,-3.124,0.811,,0.681,T,A,,1.12,,,,APO,-1.532,0.175299,0.0030719,1.02133 gb1_D272W,gb1_272,gb1,gb1,P06654,1.02137,NO,272,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.457,-5.352,3.895,,,,,,,0.234,,11.83,HAA,-1.54533,0.177985,0.00218257,1.02137 beta-lactamase_39_A235Q,beta-lactamase_39_235,TEM-1,beta-lactamase_39,P62593,1.02138,NO,235,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.266,-4.018,2.752,,0.32,E,B,0.46,-0.86,1.344,,50,OHO,-0.89,0.0495842,0.00493474,1.02138 beta-lactamase_156_E108D,beta-lactamase_156_108,TEM-1,beta-lactamase_156,P62593,1.02139,NO,108,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.46,-2.67,1.21,,0.572,G,A,1.04,1.87,8.602,8.602,72.73,PAB,-1.437,0.111618,0.00413372,1.02139 beta-lactamase_156_T131Y,beta-lactamase_156_131,TEM-1,beta-lactamase_156,P62593,1.02139,NO,131,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.328,-4.285,2.957,,,H,A,0.22,-0.69,2.031,,67.48,PPH,-1.00867,0.111618,0.00345886,1.02139 beta-lactamase_156_I244W,beta-lactamase_156_244,TEM-1,beta-lactamase_156,P62593,1.0214,NO,244,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.555,-5.375,3.82,,,E,B,0.48,-0.84,1.325,,77.62,OHH,-1.385,0.111618,0.00605379,1.0214 beta-lactamase_156_R41N,beta-lactamase_156_41,TEM-1,beta-lactamase_156,P62593,1.0214,NO,41,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-0.942,-3.445,2.503,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.111618,0.00123327,1.0214 beta-lactamase_39_L49V,beta-lactamase_39_49,TEM-1,beta-lactamase_39,P62593,1.0214,NO,49,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.897,-2.549,0.652,,0.131,T,A,0.55,0.04,13.838,13.838,64.69,AHP,-1.99233,0.0495842,0.00401477,1.0214 beta-lactamase_39_P105T,beta-lactamase_39_105,TEM-1,beta-lactamase_39,P62593,1.0214,NO,105,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.813,-3.385,2.572,,0.226,T,A,0.52,0.8,1.222,,63.29,POH,-1.01533,0.0495842,0.0011981,1.0214 beta-lactamase_39_T27Q,beta-lactamase_39_27,TEM-1,beta-lactamase_39,P62593,1.0214,NO,27,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.905,-3.929,2.024,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.0495842,0.00306559,1.0214 beta-lactamase_625_R275E,beta-lactamase_625_275,TEM-1,beta-lactamase_625,P62593,1.0214,NO,275,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.213352,0.0141984,1.0214 beta-lactamase_156_M270S,beta-lactamase_156_270,TEM-1,beta-lactamase_156,P62593,1.02141,NO,270,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.111618,0.00767762,1.02141 beta-lactamase_156_T27R,beta-lactamase_156_27,TEM-1,beta-lactamase_156,P62593,1.02142,NO,27,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.905,-3.861,1.956,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.111618,0.00306559,1.02142 beta-lactamase_A222K,beta-lactamase_222,TEM-1,beta-lactamase,P62593,1.02142,NO,222,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.103,-3.694,1.591,5.2262,0.233,H,A,0.47,-0.25,0.379,,77.62,PHH,-1.63733,0.221079,0.00466094,1.02142 beta-lactamase_K144E,beta-lactamase_144,TEM-1,beta-lactamase,P62593,1.02142,NO,144,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-2.388,-2.372,-0.016,6.02507,0.863,H,A,2.81,1.27,0.515,,77.62,OBA,-1.904,0.221079,0.00481141,1.02142 beta-lactamase_N50G,beta-lactamase_50,TEM-1,beta-lactamase,P62593,1.02142,NO,50,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-2.979,-2.053,-0.926,5.51261,0.912,T,A,1.07,1.24,1.581,,77.62,HPP,-2.134,0.221079,0.0047211,1.02142 beta-lactamase_0_A77V,beta-lactamase_0_77,TEM-1,beta-lactamase_0,P62593,1.02143,NO,77,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.234,-2.654,1.42,,0.039,H,A,0.46,-0.56,2.591,,64.34,OHH,-1.294,0.0500837,0.00282362,1.02143 beta-lactamase_156_S256N,beta-lactamase_156_256,TEM-1,beta-lactamase_156,P62593,1.02144,NO,256,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.111618,0.00710634,1.02144 beta-lactamase_2500_I171F,beta-lactamase_2500_171,TEM-1,beta-lactamase_2500,P62593,1.02144,NO,171,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-2.431,-3.175,0.744,,0.361,,B,0.48,0.53,1.66,,77.62,HHO,-1.55533,0.361275,0.00623355,1.02144 beta-lactamase_39_P60C,beta-lactamase_39_60,TEM-1,beta-lactamase_39,P62593,1.02144,NO,60,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-2.469,-4.889,2.42,,0.256,T,A,0.52,-0.56,21.37,21.37,77.62,BOA,-1.97633,0.0495842,0.00521318,1.02144 beta-lactamase_625_L28K,beta-lactamase_625_28,TEM-1,beta-lactamase_625,P62593,1.02148,NO,28,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.579,-3.608,2.029,,0.277,H,A,0.55,-0.16,2.716,,93.01,PHH,-2.11333,0.213352,0.00359321,1.02148 PSD95pdz3_N381G,PSD95pdz3_381,PSD95pdz3,PSD95pdz3,P31016,1.02148,NO,381,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-1.41,-2.59,1.18,5.66057,,,,,28.2162,,,,BPH,-1.37767,0.0758425,0.000265374,1.02148 beta-lactamase_39_E166L,beta-lactamase_39_166,TEM-1,beta-lactamase_39,P62593,1.0215,NO,166,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.756,-2.872,1.116,,0.508,G,A,1.04,1.05,17.227,17.227,73.08,OAH,-1.42233,0.0495842,0.00512989,1.0215 kka2_1:2_A229T,kka2_1:2_229,Kka2,kka2_1:2,P00552,1.0215,NO,229,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.739,-2.302,0.563,,0.32,H,A,0.46,-0.7,6.549,,63.64,HHA,-1.851,0.295029,0.00942138,1.0215 beta-lactamase_0_H287F,beta-lactamase_0_287,TEM-1,beta-lactamase_0,P62593,1.02151,NO,287,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,,,,,,,,,,,,,BBH,-1.111,0.0500837,,1.02151 beta-lactamase_39_M66V,beta-lactamase_39_66,TEM-1,beta-lactamase_39,P62593,1.02151,NO,66,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.362,-2.395,1.033,,0.013,,A,0.55,-0.7,1.319,,73.08,OHH,-1.49567,0.0495842,0.00412876,1.02151 beta-lactamase_39_R41C,beta-lactamase_39_41,TEM-1,beta-lactamase_39,P62593,1.02151,NO,41,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-0.942,-5.05,4.108,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.0495842,0.00123327,1.02151 beta-lactamase_39_T69L,beta-lactamase_39_69,TEM-1,beta-lactamase_39,P62593,1.02152,NO,69,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-0.973,-3.213,2.24,,,G,A,0.22,-1.24,4.194,,93.01,PPH,-1.01833,0.0495842,0.00127498,1.02152 beta-lactamase_156_R275I,beta-lactamase_156_275,TEM-1,beta-lactamase_156,P62593,1.02153,NO,275,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.397,-4.133,2.736,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.111618,0.0141984,1.02153 beta-lactamase_156_V29A,beta-lactamase_156_29,TEM-1,beta-lactamase_156,P62593,1.02153,NO,29,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-2.856,-2.61,-0.246,,0.733,H,A,0.44,-0.78,3.685,,93.01,HHB,-2.24733,0.111618,0.00318969,1.02153 beta-lactamase_39_R63L,beta-lactamase_39_63,TEM-1,beta-lactamase_39,P62593,1.02153,NO,63,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-0.943,-2.476,1.533,,0.218,,B,1.2,-0.31,0.326,,44.06,ABH,-0.992333,0.0495842,0.00126938,1.02153 beta-lactamase_A148R,beta-lactamase_148,TEM-1,beta-lactamase,P62593,1.02153,NO,148,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.757,-2.456,0.699,5.28111,0.379,H,A,0.52,-0.55,2.117,,72.73,PHH,-1.40167,0.221079,0.00547053,1.02153 beta-lactamase_156_D155E,beta-lactamase_156_155,TEM-1,beta-lactamase_156,P62593,1.02154,NO,155,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.889,-2.299,1.41,,0.049,,B,0.75,-0.9,0.315,,64.69,OAB,-1.62267,0.111618,0.00135315,1.02154 PSD95pdz3_K393S,PSD95pdz3_393,PSD95pdz3,PSD95pdz3,P31016,1.02154,NO,393,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.416,-2.842,1.426,5.42682,,,,,22.0122,,,,HBO,-1.4265,0.0758425,0.000879298,1.02154 beta-lactamase_625_L100M,beta-lactamase_625_100,TEM-1,beta-lactamase_625,P62593,1.02155,NO,100,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.218,-4.039,2.821,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.213352,0.00413885,1.02155 beta-lactamase_625_E108C,beta-lactamase_625_108,TEM-1,beta-lactamase_625,P62593,1.02156,NO,108,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.46,-5.208,3.748,,0.572,G,A,1.04,1.87,20.151,20.151,72.73,PAB,-1.437,0.213352,0.00413372,1.02156 beta-lactamase_0_N98R,beta-lactamase_0_98,TEM-1,beta-lactamase_0,P62593,1.02157,NO,98,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-2.973,-2.618,-0.355,,0.963,G,A,0.61,1.35,14.853,14.853,77.62,PPA,-2.07867,0.0500837,0.00505389,1.02157 beta-lactamase_39_H287N,beta-lactamase_39_287,TEM-1,beta-lactamase_39,P62593,1.02157,NO,287,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,,,,,,,,,,,,,BBH,-1.111,0.0495842,,1.02157 beta-lactamase_A15W,beta-lactamase_15,TEM-1,beta-lactamase,P62593,1.02157,NO,15,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.654,-5.306,3.652,,,,,,,31.998,31.998,93.01,HHH,-2.10833,0.221079,0.00248966,1.02157 beta-lactamase_39_E46H,beta-lactamase_39_46,TEM-1,beta-lactamase_39,P62593,1.02158,NO,46,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.94,-4.828,2.888,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.0495842,0.00427568,1.02158 kka2_1:8_Y218H,kka2_1:8_218,Kka2,kka2_1:8,P00552,1.02158,NO,218,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-1.438,-1.83,0.392,,0.122,H,A,1.25,-0.69,2.923,,56.06,BHP,-1.17533,0.100394,0.0126098,1.02158 kka2_1:8_Y218H,kka2_1:8_218,Kka2,kka2_1:8,P00552,1.02158,NO,218,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-1.438,-1.83,0.392,,0.122,H,A,1.25,-0.69,2.923,,56.06,BHP,-1.17533,0.100394,0.0126098,1.02158 beta-lactamase_0_A77Q,beta-lactamase_0_77,TEM-1,beta-lactamase_0,P62593,1.02159,NO,77,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.234,-4.052,2.818,,0.039,H,A,0.46,-0.56,2.591,,64.34,OHH,-1.294,0.0500837,0.00282362,1.02159 beta-lactamase_39_E108M,beta-lactamase_39_108,TEM-1,beta-lactamase_39,P62593,1.02159,NO,108,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.46,-4.775,3.315,,0.572,G,A,1.04,1.87,20.151,20.151,72.73,PAB,-1.437,0.0495842,0.00413372,1.02159 beta-lactamase_2500_G90Q,beta-lactamase_2500_90,TEM-1,beta-lactamase_2500,P62593,1.0216,NO,90,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-2.091,-2.862,0.771,,0.598,T,A,0.29,0.32,1.2,,77.62,HOB,-1.52633,0.361275,0.00490273,1.0216 beta-lactamase_39_G85F,beta-lactamase_39_85,TEM-1,beta-lactamase_39,P62593,1.0216,NO,85,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.011,-4.377,3.366,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.0495842,0.00252173,1.0216 beta-lactamase_39_S221G,beta-lactamase_39_221,TEM-1,beta-lactamase_39,P62593,1.0216,NO,221,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.754,-3.136,1.382,,0.624,H,A,0.27,-0.2,2.69,,74.48,BPH,-1.59967,0.0495842,0.0046094,1.0216 kka2_1:4_V83D,kka2_1:4_83,Kka2,kka2_1:4,P00552,1.02161,NO,83,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-2.567,-3.765,1.198,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.168804,0.00650486,1.02161 beta-lactamase_39_G253F,beta-lactamase_39_253,TEM-1,beta-lactamase_39,P62593,1.02163,NO,253,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.0495842,0.00786358,1.02163 kka2_1:8_A35S,kka2_1:8_35,Kka2,kka2_1:8,P00552,1.02163,NO,35,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.127,-2.197,0.07,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.100394,0.00630016,1.02163 kka2_1:8_A35S,kka2_1:8_35,Kka2,kka2_1:8,P00552,1.02163,NO,35,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.127,-2.197,0.07,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.100394,0.00630016,1.02163 beta-lactamase_39_T131V,beta-lactamase_39_131,TEM-1,beta-lactamase_39,P62593,1.02165,NO,131,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.328,-3.345,2.017,,,H,A,0.22,-0.69,3.306,,67.48,PPH,-1.00867,0.0495842,0.00345886,1.02165 beta-lactamase_R189Y,beta-lactamase_189,TEM-1,beta-lactamase,P62593,1.02165,NO,189,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.844,-3.134,1.29,5.74877,0.278,H,A,0.68,1.01,1.512,,72.73,HBB,-1.668,0.221079,0.0050699,1.02165 kka2_1:4_P194A,kka2_1:4_194,Kka2,kka2_1:4,P00552,1.02165,NO,194,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.846,-3.118,2.272,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.168804,0.00314194,1.02165 beta-lactamase_625_I285W,beta-lactamase_625_285,TEM-1,beta-lactamase_625,P62593,1.02166,NO,285,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.213352,0.101555,1.02166 beta-lactamase_625_L28N,beta-lactamase_625_28,TEM-1,beta-lactamase_625,P62593,1.02166,NO,28,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.579,-4.056,2.477,,0.277,H,A,0.55,-0.16,2.716,,93.01,PHH,-2.11333,0.213352,0.00359321,1.02166 beta-lactamase_156_A211W,beta-lactamase_156_211,TEM-1,beta-lactamase_156,P62593,1.02167,NO,211,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.896,-5.506,3.61,,0.369,T,A,0.46,-0.69,8.527,8.527,77.62,AHA,-1.94633,0.111618,0.00648183,1.02167 beta-lactamase_39_A282H,beta-lactamase_39_282,TEM-1,beta-lactamase_39,P62593,1.02167,NO,282,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.0495842,0.0449821,1.02167 beta-lactamase_625_E108V,beta-lactamase_625_108,TEM-1,beta-lactamase_625,P62593,1.02167,NO,108,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.46,-3.706,2.246,,0.572,G,A,1.04,1.87,20.151,20.151,72.73,PAB,-1.437,0.213352,0.00413372,1.02167 beta-lactamase_0_T126F,beta-lactamase_0_126,TEM-1,beta-lactamase_0,P62593,1.02168,NO,126,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.122,-4.199,3.077,,0.05,H,A,0.22,-0.05,0.705,,44.41,HPH,-1.60467,0.0500837,0.00244552,1.02168 beta-lactamase_156_A84L,beta-lactamase_156_84,TEM-1,beta-lactamase_156,P62593,1.02168,NO,84,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.651,-3.508,1.857,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.111618,0.00503822,1.02168 beta-lactamase_156_M270L,beta-lactamase_156_270,TEM-1,beta-lactamase_156,P62593,1.0217,NO,270,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.111618,0.00767762,1.0217 beta-lactamase_39_T178F,beta-lactamase_39_178,TEM-1,beta-lactamase_39,P62593,1.0217,NO,178,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-0.791,-4.067,3.276,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.0495842,0.000684366,1.0217 beta-lactamase_156_M270P,beta-lactamase_156_270,TEM-1,beta-lactamase_156,P62593,1.02171,NO,270,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.111618,0.00767762,1.02171 beta-lactamase_625_Q88T,beta-lactamase_625_88,TEM-1,beta-lactamase_625,P62593,1.02171,NO,88,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.086,-2.693,0.607,,0.807,,B,0.64,2.03,1.84,,77.62,APH,-1.53433,0.213352,0.00504167,1.02171 beta-lactamase_156_L73Q,beta-lactamase_156_73,TEM-1,beta-lactamase_156,P62593,1.02172,NO,73,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.507,-4.261,2.754,,,H,A,0.55,-0.64,2.09,,67.83,HHH,-1.487,0.111618,0.00488983,1.02172 beta-lactamase_625_P172H,beta-lactamase_625_172,TEM-1,beta-lactamase_625,P62593,1.02173,NO,172,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.998,-4.746,3.748,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.213352,0.00312594,1.02173 beta-lactamase_39_L160M,beta-lactamase_39_160,TEM-1,beta-lactamase_39,P62593,1.02174,NO,160,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.977,-3.902,2.925,,0.022,,B,0.55,-0.6,0.895,,44.41,BHA,-0.936,0.0495842,0.00193775,1.02174 beta-lactamase_156_L191C,beta-lactamase_156_191,TEM-1,beta-lactamase_156,P62593,1.02175,NO,191,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.087,-4.696,3.609,,,H,A,0.55,0.09,1.372,,63.29,BHH,-1.445,0.111618,0.00263549,1.02175 beta-lactamase_39_A235R,beta-lactamase_39_235,TEM-1,beta-lactamase_39,P62593,1.02179,NO,235,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.266,-3.887,2.621,,0.32,E,B,0.46,-0.86,1.344,,50,OHO,-0.89,0.0495842,0.00493474,1.02179 gb1_I232G,gb1_232,gb1,gb1,P06654,1.02179,NO,232,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-2.175,-2.025,-0.15,,,,,,,0.766,,44.87,HHH,-2.152,0.177985,0.00580459,1.02179 beta-lactamase_39_V78L,beta-lactamase_39_78,TEM-1,beta-lactamase_39,P62593,1.0218,NO,78,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.459,-1.714,0.255,,,H,A,0.44,-0.47,1.132,,63.64,HHH,-1.17833,0.0495842,0.00492501,1.0218 beta-lactamase_39_T193D,beta-lactamase_39_193,TEM-1,beta-lactamase_39,P62593,1.02181,NO,193,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.914,-3.815,1.901,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.0495842,0.00482669,1.02181 beta-lactamase_39_T131R,beta-lactamase_39_131,TEM-1,beta-lactamase_39,P62593,1.02182,NO,131,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.328,-2.888,1.56,,,H,A,0.22,-0.69,3.306,,67.48,PPH,-1.00867,0.0495842,0.00345886,1.02182 beta-lactamase_156_A225M,beta-lactamase_156_225,TEM-1,beta-lactamase_156,P62593,1.02184,NO,225,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.845,-4.778,2.933,,1,T,B,0.46,-0.38,11.722,11.722,74.48,OHO,-1.39967,0.111618,0.00465057,1.02184 beta-lactamase_625_I45A,beta-lactamase_625_45,TEM-1,beta-lactamase_625,P62593,1.02184,NO,45,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-2.421,-2.001,-0.42,,,E,B,0.48,-0.3,3.642,,77.62,HHA,-2.30267,0.213352,0.00452842,1.02184 PSD95pdz3_G356F,PSD95pdz3_356,PSD95pdz3,PSD95pdz3,P31016,1.02185,NO,356,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.008,-3.974,2.966,4.8656,,,,,11.9575,,,,BOA,-1.22933,0.0758425,0.000623061,1.02185 PSD95pdz3_G383V,PSD95pdz3_383,PSD95pdz3,PSD95pdz3,P31016,1.02185,NO,383,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.008,-3.435,2.427,5.17213,,,,,20.5325,,,,HOP,-1.338,0.0758425,0.000233044,1.02185 beta-lactamase_0_M270K,beta-lactamase_0_270,TEM-1,beta-lactamase_0,P62593,1.02186,NO,270,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.0500837,0.00767762,1.02186 PSD95pdz3_Q384A,PSD95pdz3_384,PSD95pdz3,PSD95pdz3,P31016,1.02186,NO,384,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-1.699,-2.759,1.06,5.49339,,,,,23.54,,,,OPP,-1.41333,0.0758425,0.000216736,1.02186 beta-lactamase_2500_E108M,beta-lactamase_2500_108,TEM-1,beta-lactamase_2500,P62593,1.02188,NO,108,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.46,-4.775,3.315,,0.572,G,A,1.04,1.87,1.147,,72.73,PAB,-1.437,0.361275,0.00413372,1.02188 beta-lactamase_39_A282M,beta-lactamase_39_282,TEM-1,beta-lactamase_39,P62593,1.02191,NO,282,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.0495842,0.0449821,1.02191 beta-lactamase_625_S221M,beta-lactamase_625_221,TEM-1,beta-lactamase_625,P62593,1.02191,NO,221,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.754,-4.595,2.841,,0.624,H,A,0.27,-0.2,1.495,,74.48,BPH,-1.59967,0.213352,0.0046094,1.02191 Pab1_A185I,Pab1_185,Pab1,Pab1,P04147,1.02191,NO,185,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.702,-3.775,2.073,,,,,,,1.756,,63.26,AHH,-1.66167,0.175299,0.00144499,1.02191 beta-lactamase_E61G,beta-lactamase_61,TEM-1,beta-lactamase,P62593,1.02192,NO,61,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.115,-2.393,0.278,6.29701,0.775,T,a,0.52,1.29,1.975,,77.62,OAA,-1.92567,0.221079,0.00440955,1.02192 beta-lactamase_H5M,beta-lactamase_5,TEM-1,beta-lactamase,P62593,1.02192,NO,5,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-2.698,-3.116,0.418,,,,,,,1.865,,72.73,PBH,-2.36967,0.221079,0.00292712,1.02192 beta-lactamase_I206Y,beta-lactamase_206,TEM-1,beta-lactamase,P62593,1.02192,NO,206,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-2.429,-4.278,1.849,5.3727,0.173,H,A,1,-0.34,2.061,,77.62,HHA,-1.805,0.221079,0.00528934,1.02192 beta-lactamase_I93I,beta-lactamase_93,TEM-1,beta-lactamase,P62593,1.02192,NO,93,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.401,-1.401,,5.74695,0.128,E,B,0.77,0.44,1.757,,67.83,BHB,-1.873,0.221079,0.00527066,1.02192 beta-lactamase_L192M,beta-lactamase_192,TEM-1,beta-lactamase,P62593,1.02192,NO,192,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.254,-4.084,2.83,5.68899,0.095,H,A,1.3,0.35,1.756,,60.14,HHP,-1.41833,0.221079,0.00558728,1.02192 beta-lactamase_M153C,beta-lactamase_153,TEM-1,beta-lactamase,P62593,1.02192,NO,153,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-3.193,-4.79,1.597,5.46509,0.14,T,A,1.07,-0.11,2.061,,77.62,PHO,-2.25767,0.221079,0.00509109,1.02192 beta-lactamase_M153W,beta-lactamase_153,TEM-1,beta-lactamase,P62593,1.02192,NO,153,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-3.193,-5.376,2.183,5.46509,0.14,T,A,1.07,-0.11,2.061,,77.62,PHO,-2.25767,0.221079,0.00509109,1.02192 beta-lactamase_156_A211S,beta-lactamase_156_211,TEM-1,beta-lactamase_156,P62593,1.02193,NO,211,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.896,-2.788,0.892,,0.369,T,A,0.46,-0.69,8.527,8.527,77.62,AHA,-1.94633,0.111618,0.00648183,1.02193 beta-lactamase_39_T193R,beta-lactamase_39_193,TEM-1,beta-lactamase_39,P62593,1.02193,NO,193,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.914,-4.014,2.1,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.0495842,0.00482669,1.02193 beta-lactamase_156_I171W,beta-lactamase_156_171,TEM-1,beta-lactamase_156,P62593,1.02194,NO,171,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-2.431,-5.376,2.945,,0.361,,B,0.48,0.53,3.869,,77.62,HHO,-1.55533,0.111618,0.00623355,1.02194 Pab1_P135V,Pab1_135,Pab1,Pab1,P04147,1.02195,NO,135,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.457,-3.372,1.915,,,,,,,6.41,,81.8,BOA,-1.53367,0.175299,0.00148028,1.02195 beta-lactamase_625_I45M,beta-lactamase_625_45,TEM-1,beta-lactamase_625,P62593,1.02197,NO,45,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-2.421,-3.375,0.954,,,E,B,0.48,-0.3,3.642,,77.62,HHA,-2.30267,0.213352,0.00452842,1.02197 kka2_1:2_R143L,kka2_1:2_143,Kka2,kka2_1:2,P00552,1.02198,NO,143,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.525,-2.21,-0.315,,0.325,H,A,0.16,1.22,14.853,14.853,65.53,ABH,-1.86833,0.295029,0.00662247,1.02198 beta-lactamase_156_Q37C,beta-lactamase_156_37,TEM-1,beta-lactamase_156,P62593,1.02199,NO,37,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.134,-5.133,2.999,,0.613,H,A,0.64,1.98,12.052,12.052,73.08,APH,-2.06967,0.111618,0.00425833,1.02199 beta-lactamase_39_R220F,beta-lactamase_39_220,TEM-1,beta-lactamase_39,P62593,1.02199,NO,220,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-0.942,-4.29,3.348,,0.295,I,A,1.2,-0.76,1.596,,74.48,HBP,-1.33633,0.0495842,0.00232421,1.02199 beta-lactamase_156_D231Q,beta-lactamase_156_231,TEM-1,beta-lactamase_156,P62593,1.022,NO,231,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.816,-3.637,2.821,,,E,B,0.75,-1.06,2.66,,65.38,HAB,-0.994,0.111618,0.00107395,1.022 beta-lactamase_625_R91Q,beta-lactamase_625_91,TEM-1,beta-lactamase_625,P62593,1.022,NO,91,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.392,-2.363,0.971,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.213352,0.00380226,1.022 beta-lactamase_156_V106G,beta-lactamase_156_106,TEM-1,beta-lactamase_156,P62593,1.02201,NO,106,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.218,-3.752,2.534,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.111618,0.00304168,1.02201 beta-lactamase_156_T187F,beta-lactamase_156_187,TEM-1,beta-lactamase_156,P62593,1.02202,NO,187,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.401,-4.141,2.74,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.111618,0.00491782,1.02202 kka2_1:4_A56S,kka2_1:4_56,Kka2,kka2_1:4,P00552,1.02202,NO,56,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.083,-2.605,0.522,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.168804,0.00717715,1.02202 beta-lactamase_625_F58T,beta-lactamase_625_58,TEM-1,beta-lactamase_625,P62593,1.02203,NO,58,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-2.914,-2.91,-0.004,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.213352,0.00523369,1.02203 beta-lactamase_156_A211G,beta-lactamase_156_211,TEM-1,beta-lactamase_156,P62593,1.02204,NO,211,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.896,-2.355,0.459,,0.369,T,A,0.46,-0.69,8.527,8.527,77.62,AHA,-1.94633,0.111618,0.00648183,1.02204 beta-lactamase_156_G39Y,beta-lactamase_156_39,TEM-1,beta-lactamase_156,P62593,1.02205,NO,39,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.864,-4.383,2.519,,0.701,T,L,0.29,0.47,1.454,,77.62,HOH,-1.53633,0.111618,0.00487611,1.02205 beta-lactamase_39_G141M,beta-lactamase_39_141,TEM-1,beta-lactamase_39,P62593,1.02206,NO,141,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.828,-4.966,4.138,,0.575,T,l,0.29,-0.28,0.722,,64.69,HOO,-1.08933,0.0495842,0.0012419,1.02206 gb1_K236N,gb1_236,gb1,gb1,P06654,1.02207,NO,236,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-2.119,-1.902,-0.217,,,,,,,1.083,,45.54,OBP,-1.758,0.177985,0.00255408,1.02207 beta-lactamase_A225P,beta-lactamase_225,TEM-1,beta-lactamase,P62593,1.02208,NO,225,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.845,-3.112,1.267,6.5181,1,T,B,0.58,-0.38,4.077,,74.48,OHO,-1.39967,0.221079,0.00465057,1.02208 beta-lactamase_156_R118A,beta-lactamase_156_118,TEM-1,beta-lactamase_156,P62593,1.02209,NO,118,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.413,-1.798,-0.615,,0.457,H,A,1.2,1.39,2.231,,77.62,HBA,-1.785,0.111618,0.00538794,1.02209 beta-lactamase_39_P60E,beta-lactamase_39_60,TEM-1,beta-lactamase_39,P62593,1.02209,NO,60,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-2.469,-2.856,0.387,,0.256,T,A,0.52,-0.56,21.37,21.37,77.62,BOA,-1.97633,0.0495842,0.00521318,1.02209 beta-lactamase_39_L223Y,beta-lactamase_39_223,TEM-1,beta-lactamase_39,P62593,1.0221,NO,223,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.055,-3.889,2.834,,0.27,,B,0.55,0.09,1.511,,74.48,HHO,-1.35033,0.0495842,0.00372793,1.0221 E1_Ubiquitin_Q41V,E1_Ubiquitin_41,Uba1,E1_Ubiquitin,P0CG63,1.0221,NO,41,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-1.25,-3.346,2.096,,0.017,E,B,,-0.98,,,,PPB,-1.344,0.18783,0.00215097,1.0221 beta-lactamase_39_A278N,beta-lactamase_39_278,TEM-1,beta-lactamase_39,P62593,1.02211,NO,278,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.0495842,0.0310297,1.02211 beta-lactamase_39_P25N,beta-lactamase_39_25,TEM-1,beta-lactamase_39,P62593,1.02212,NO,25,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.526,-3.702,2.176,,0.624,H,A,0.52,0.14,1.157,,73.08,BOA,-2.15367,0.0495842,0.00347571,1.02212 beta-lactamase_I206I,beta-lactamase_206,TEM-1,beta-lactamase,P62593,1.02212,NO,206,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-2.429,-2.429,,5.3727,0.173,H,A,1,-0.34,2.061,,77.62,HHA,-1.805,0.221079,0.00528934,1.02212 kka2_1:4_E96P,kka2_1:4_96,Kka2,kka2_1:4,P00552,1.02213,NO,96,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.573,-3.855,1.282,,0.476,,B,1.52,-0.65,1.254,,71.59,OAH,-2.143,0.168804,0.00369441,1.02213 beta-lactamase_39_L218W,beta-lactamase_39_218,TEM-1,beta-lactamase_39,P62593,1.02214,NO,218,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.391,-5.26,3.869,,,I,b,0.55,-0.53,2.038,,74.48,OHH,-1.58867,0.0495842,0.00618274,1.02214 beta-lactamase_39_T187A,beta-lactamase_39_187,TEM-1,beta-lactamase_39,P62593,1.02215,NO,187,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.401,-3.072,1.671,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.0495842,0.00491782,1.02215 beta-lactamase_39_V157P,beta-lactamase_39_157,TEM-1,beta-lactamase_39,P62593,1.02215,NO,157,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.751,-4.03,2.279,,0.308,S,a,0.44,-0.75,10.364,10.364,69.58,BHP,-2.00767,0.0495842,0.00506849,1.02215 beta-lactamase_156_E195A,beta-lactamase_156_195,TEM-1,beta-lactamase_156,P62593,1.02216,NO,195,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.186,-2.778,0.592,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.111618,0.00496565,1.02216 beta-lactamase_156_S201L,beta-lactamase_156_201,TEM-1,beta-lactamase_156,P62593,1.02217,NO,201,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.183,-2.615,1.432,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.111618,0.00198815,1.02217 beta-lactamase_156_V106L,beta-lactamase_156_106,TEM-1,beta-lactamase_156,P62593,1.02217,NO,106,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.218,-2.154,0.936,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.111618,0.00304168,1.02217 kka2_1:8_D101Q,kka2_1:8_101,Kka2,kka2_1:8,P00552,1.02218,NO,101,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.028,-3.859,2.831,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.100394,0.00423361,1.02218 kka2_1:8_D101Q,kka2_1:8_101,Kka2,kka2_1:8,P00552,1.02218,NO,101,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.028,-3.859,2.831,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.100394,0.00423361,1.02218 beta-lactamase_156_P217E,beta-lactamase_156_217,TEM-1,beta-lactamase_156,P62593,1.0222,NO,217,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-2.062,-2.651,0.589,,0.496,I,A,0.52,-0.33,2.303,,74.48,OOH,-1.64333,0.111618,0.00463211,1.0222 beta-lactamase_625_I140A,beta-lactamase_625_140,TEM-1,beta-lactamase_625,P62593,1.0222,NO,140,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.733,-3.145,1.412,,0.128,H,A,0.48,0.41,1.628,,73.08,PHO,-1.48733,0.213352,0.00597777,1.0222 beta-lactamase_625_K109Q,beta-lactamase_625_109,TEM-1,beta-lactamase_625,P62593,1.0222,NO,109,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.734,-2.855,1.121,,0.787,G,A,2.34,2.21,7.243,,72.73,ABB,-1.63333,0.213352,0.00462493,1.0222 kka2_1:4_D250Q,kka2_1:4_250,Kka2,kka2_1:4,P00552,1.0222,NO,250,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.015,-2.867,1.852,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.168804,0.0177103,1.0222 gb1_T275V,gb1_275,gb1,gb1,P06654,1.02221,NO,275,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.727,-3.16,1.433,,,,,,,0.511,,35.71,HPB,-1.637,0.177985,0.00606618,1.02221 beta-lactamase_625_T186N,beta-lactamase_625_186,TEM-1,beta-lactamase_625,P62593,1.02222,NO,186,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.522,-3.756,1.234,,0.396,H,A,0.22,-0.28,0.515,,77.62,HPP,-1.77633,0.213352,0.00485034,1.02222 beta-lactamase_A9S,beta-lactamase_9,TEM-1,beta-lactamase,P62593,1.02223,NO,9,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.147,-2.694,0.547,,,,,,,5.128,,72.73,HHH,-2.04267,0.221079,0.00247263,1.02223 beta-lactamase_L196A,beta-lactamase_196,TEM-1,beta-lactamase,P62593,1.02223,NO,196,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-2.478,-1.974,-0.504,,0.518,S,A,0.55,1.35,,,77.62,AHH,-1.839,0.221079,0.00512144,1.02223 beta-lactamase_T198T,beta-lactamase_198,TEM-1,beta-lactamase,P62593,1.02223,NO,198,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.168,-2.168,,4.9209,0.489,,B,0.69,-0.13,0.37,,73.78,HPH,-1.98767,0.221079,0.004311,1.02223 beta-lactamase_156_T27C,beta-lactamase_156_27,TEM-1,beta-lactamase_156,P62593,1.02224,NO,27,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.905,-4.927,3.022,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.111618,0.00306559,1.02224 beta-lactamase_2500_A282K,beta-lactamase_2500_282,TEM-1,beta-lactamase_2500,P62593,1.02224,NO,282,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.361275,0.0449821,1.02224 beta-lactamase_39_E87T,beta-lactamase_39_87,TEM-1,beta-lactamase_39,P62593,1.02224,NO,87,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.421,-2.787,1.366,,0.048,,B,1.04,0.92,15.231,15.231,64.69,PAP,-1.969,0.0495842,0.00337888,1.02224 beta-lactamase_39_T27A,beta-lactamase_39_27,TEM-1,beta-lactamase_39,P62593,1.02224,NO,27,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.905,-2.5,0.595,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.0495842,0.00306559,1.02224 beta-lactamase_625_N50M,beta-lactamase_625_50,TEM-1,beta-lactamase_625,P62593,1.02224,NO,50,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-2.979,-4.727,1.748,,0.912,T,A,0.61,1.24,3.446,,77.62,HPP,-2.134,0.213352,0.0047211,1.02224 kka2_1:2_M1T,kka2_1:2_1,Kka2,kka2_1:2,P00552,1.02224,NO,1,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.787,-3.152,1.365,,,,,,,1.347,,62.12,NAHH,-1.787,0.295029,0.00251939,1.02224 beta-lactamase_0_A170L,beta-lactamase_0_170,TEM-1,beta-lactamase_0,P62593,1.02225,NO,170,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.237,-3.289,2.052,,0.126,,L,0.46,-0.35,2.427,,64.69,AHH,-1.63267,0.0500837,0.00431903,1.02225 beta-lactamase_S80Y,beta-lactamase_80,TEM-1,beta-lactamase,P62593,1.02225,NO,80,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.029,-4.297,2.268,5.23748,0.192,H,A,0.25,0.46,2.256,,77.62,HPB,-1.44567,0.221079,0.00565569,1.02225 beta-lactamase_39_R41Y,beta-lactamase_39_41,TEM-1,beta-lactamase_39,P62593,1.02226,NO,41,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-0.942,-4.188,3.246,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.0495842,0.00123327,1.02226 beta-lactamase_2500_S51D,beta-lactamase_2500_51,TEM-1,beta-lactamase_2500,P62593,1.02227,NO,51,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.526,-2.756,1.23,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.361275,0.00504821,1.02227 beta-lactamase_G194G,beta-lactamase_194,TEM-1,beta-lactamase,P62593,1.02228,NO,194,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.396,-1.396,,5.46622,0.276,S,b,0.77,0.36,3.593,,67.83,POA,-1.832,0.221079,0.00392163,1.02228 beta-lactamase_156_F228C,beta-lactamase_156_228,TEM-1,beta-lactamase_156,P62593,1.02229,NO,228,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-2.342,-5.075,2.733,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.111618,0.0046669,1.02229 beta-lactamase_156_P217C,beta-lactamase_156_217,TEM-1,beta-lactamase_156,P62593,1.02229,NO,217,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-2.062,-5.064,3.002,,0.496,I,A,0.52,-0.33,2.303,,74.48,OOH,-1.64333,0.111618,0.00463211,1.02229 beta-lactamase_39_A282K,beta-lactamase_39_282,TEM-1,beta-lactamase_39,P62593,1.02229,NO,282,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.0495842,0.0449821,1.02229 PSD95pdz3_D366W,PSD95pdz3_366,PSD95pdz3,PSD95pdz3,P31016,1.02229,NO,366,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.264,-5.229,3.965,5.55684,,,,,20.2375,,,,HAH,-1.401,0.0758425,0.000481272,1.02229 beta-lactamase_39_L196H,beta-lactamase_39_196,TEM-1,beta-lactamase_39,P62593,1.0223,NO,196,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-2.478,-3.478,1,,0.518,S,A,0.55,1.35,12.152,12.152,77.62,AHH,-1.839,0.0495842,0.00512144,1.0223 beta-lactamase_625_I45S,beta-lactamase_625_45,TEM-1,beta-lactamase_625,P62593,1.0223,NO,45,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-2.421,-2.717,0.296,,,E,B,0.48,-0.3,3.642,,77.62,HHA,-2.30267,0.213352,0.00452842,1.0223 beta-lactamase_0_G90N,beta-lactamase_0_90,TEM-1,beta-lactamase_0,P62593,1.02231,NO,90,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-2.091,-2.941,0.85,,0.598,T,A,0.29,0.32,2.04,,77.62,HOB,-1.52633,0.0500837,0.00490273,1.02231 beta-lactamase_156_K109T,beta-lactamase_156_109,TEM-1,beta-lactamase_156,P62593,1.02231,NO,109,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.734,-2.559,0.825,,0.787,G,A,2.34,2.21,6.031,,72.73,ABB,-1.63333,0.111618,0.00462493,1.02231 beta-lactamase_39_A215F,beta-lactamase_39_215,TEM-1,beta-lactamase_39,P62593,1.02231,NO,215,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.503,-4.278,2.775,,,,a,0.46,-0.93,0.494,,74.48,HHO,-1.42633,0.0495842,0.00544007,1.02231 beta-lactamase_0_Q204K,beta-lactamase_0_204,TEM-1,beta-lactamase_0,P62593,1.02232,NO,204,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-1.382,-2.218,0.836,,0.204,H,A,0.64,0.09,2.646,,66.08,PPH,-1.49067,0.0500837,0.00364106,1.02232 beta-lactamase_156_S256K,beta-lactamase_156_256,TEM-1,beta-lactamase_156,P62593,1.02232,NO,256,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.111618,0.00710634,1.02232 beta-lactamase_39_T112M,beta-lactamase_39_112,TEM-1,beta-lactamase_39,P62593,1.02233,NO,112,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.186,-4.812,2.626,,0.921,T,A,0.22,1.06,2.87,,73.78,HPA,-1.925,0.0495842,0.00531334,1.02233 beta-lactamase_156_E35D,beta-lactamase_156_35,TEM-1,beta-lactamase_156,P62593,1.02234,NO,35,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-0.869,-2.219,1.35,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.111618,0.00174441,1.02234 beta-lactamase_39_L49H,beta-lactamase_39_49,TEM-1,beta-lactamase_39,P62593,1.02234,NO,49,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.897,-4.794,2.897,,0.131,T,A,0.55,0.04,13.838,13.838,64.69,AHP,-1.99233,0.0495842,0.00401477,1.02234 kka2_1:8_C209L,kka2_1:8_209,Kka2,kka2_1:8,P00552,1.02234,NO,209,C,L,CL,Special,Hydrophobic,5.07,9.7088,4.6388,198,121,131,10,108.5,166.7,58.2,-0.906,-2.447,1.541,,,,a,1.5,-0.89,0.391,,19.32,AOO,-0.903,0.100394,0.00260862,1.02234 kka2_1:8_C209L,kka2_1:8_209,Kka2,kka2_1:8,P00552,1.02234,NO,209,C,L,CL,Special,Hydrophobic,5.07,9.7088,4.6388,198,121,131,10,108.5,166.7,58.2,-0.906,-2.447,1.541,,,,a,1.5,-0.89,0.391,,19.32,AOO,-0.903,0.100394,0.00260862,1.02234 beta-lactamase_F22F,beta-lactamase_22,TEM-1,beta-lactamase,P62593,1.02235,NO,22,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-2.676,-2.676,,,,,,,,1.616,,73.08,HHH,-2.03233,0.221079,0.00262842,1.02235 gb1_Q258H,gb1_258,gb1,gb1,P06654,1.02235,NO,258,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.095,-4.177,2.082,,,,,,,0.86,,37.28,BPH,-1.88333,0.177985,0.00437595,1.02235 beta-lactamase_0_R239C,beta-lactamase_0_239,TEM-1,beta-lactamase_0,P62593,1.02237,NO,239,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.0500837,0.00213852,1.02237 kka2_1:8_R18Q,kka2_1:8_18,Kka2,kka2_1:8,P00552,1.02237,NO,18,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.055,-2.59,0.535,,0.474,T,A,1.2,0.54,19.629,19.629,71.59,ABH,-1.821,0.100394,0.00724065,1.02237 kka2_1:8_R18Q,kka2_1:8_18,Kka2,kka2_1:8,P00552,1.02237,NO,18,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.055,-2.59,0.535,,0.474,T,A,1.2,0.54,19.629,19.629,71.59,ABH,-1.821,0.100394,0.00724065,1.02237 beta-lactamase_S254Q,beta-lactamase_254,TEM-1,beta-lactamase,P62593,1.02238,NO,254,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.126,-3.813,1.687,5.49575,0.312,,a,0.25,-0.48,24.91,24.91,69.58,OPB,-2.215,0.221079,0.00369,1.02238 beta-lactamase_39_T27P,beta-lactamase_39_27,TEM-1,beta-lactamase_39,P62593,1.02239,NO,27,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.905,-1.921,0.016,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.0495842,0.00306559,1.02239 beta-lactamase_625_P217K,beta-lactamase_625_217,TEM-1,beta-lactamase_625,P62593,1.02239,NO,217,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-2.062,-2.687,0.625,,0.496,I,A,0.52,-0.33,1.087,,74.48,OOH,-1.64333,0.213352,0.00463211,1.02239 beta-lactamase_39_N168L,beta-lactamase_39_168,TEM-1,beta-lactamase_39,P62593,1.0224,NO,168,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-1.029,-3.516,2.487,,0.113,G,A,0.61,-0.4,0.822,,44.41,HPA,-1.13233,0.0495842,0.00288667,1.0224 beta-lactamase_39_V157R,beta-lactamase_39_157,TEM-1,beta-lactamase_39,P62593,1.0224,NO,157,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.751,-3.07,1.319,,0.308,S,a,0.44,-0.75,10.364,10.364,69.58,BHP,-2.00767,0.0495842,0.00506849,1.0224 beta-lactamase_156_I93T,beta-lactamase_156_93,TEM-1,beta-lactamase_156,P62593,1.02241,NO,93,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.401,-2.729,1.328,,0.128,E,B,0.48,0.44,1.524,,67.83,BHB,-1.873,0.111618,0.00527066,1.02241 beta-lactamase_625_T186V,beta-lactamase_625_186,TEM-1,beta-lactamase_625,P62593,1.02241,NO,186,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.522,-3.557,1.035,,0.396,H,A,0.22,-0.28,0.515,,77.62,HPP,-1.77633,0.213352,0.00485034,1.02241 kka2_1:8_A137I,kka2_1:8_137,Kka2,kka2_1:8,P00552,1.02241,NO,137,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.156,-2.375,0.219,,0.029,H,A,1.04,0.34,2.886,,63.26,PHB,-2.559,0.100394,0.00515054,1.02241 kka2_1:8_A137I,kka2_1:8_137,Kka2,kka2_1:8,P00552,1.02241,NO,137,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.156,-2.375,0.219,,0.029,H,A,1.04,0.34,2.886,,63.26,PHB,-2.559,0.100394,0.00515054,1.02241 beta-lactamase_156_A84R,beta-lactamase_156_84,TEM-1,beta-lactamase_156,P62593,1.02244,NO,84,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.651,-2.603,0.952,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.111618,0.00503822,1.02244 beta-lactamase_156_R92D,beta-lactamase_156_92,TEM-1,beta-lactamase_156,P62593,1.02244,NO,92,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.718,-3.708,1.99,,0.479,E,B,1.2,1.36,19.112,19.112,65.38,BBH,-1.50367,0.111618,0.00429626,1.02244 beta-lactamase_39_P25H,beta-lactamase_39_25,TEM-1,beta-lactamase_39,P62593,1.02245,NO,25,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.526,-4.604,3.078,,0.624,H,A,0.52,0.14,1.157,,73.08,BOA,-2.15367,0.0495842,0.00347571,1.02245 beta-lactamase_H24K,beta-lactamase_24,TEM-1,beta-lactamase,P62593,1.02245,NO,24,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-2.481,-3.455,0.974,5.82767,,,,,,2.708,,93.01,HBO,-1.85167,0.221079,0.00238894,1.02245 beta-lactamase_39_M67L,beta-lactamase_39_67,TEM-1,beta-lactamase_39,P62593,1.02247,NO,67,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-2.231,-2.657,0.426,,0.006,G,P,0.55,-0.81,1.463,,65.03,HHP,-1.502,0.0495842,0.00409753,1.02247 PSD95pdz3_T385W,PSD95pdz3_385,PSD95pdz3,PSD95pdz3,P31016,1.02247,NO,385,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.533,-4.958,3.425,5.57157,,,,,23.6871,4.527,,87.71,PPH,-1.56567,0.0758425,0.000545119,1.02247 PSD95pdz3_G319T,PSD95pdz3_319,PSD95pdz3,PSD95pdz3,P31016,1.02248,NO,319,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.008,-3.328,2.32,4.95387,,,,,18.8725,,,,BOP,-1.36967,0.0758425,0.00109317,1.02248 WW_domain_D194T,WW_domain_194,Yap65,WW_domain,P46937,1.02248,NO,194,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.536,-3.326,1.79,5.95614,,,,,,1.948,,74.4,HAP,-1.78933,0.153962,0.00483742,1.02248 beta-lactamase_39_V72L,beta-lactamase_39_72,TEM-1,beta-lactamase_39,P62593,1.0225,NO,72,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.658,-2.403,0.745,,,H,A,0.44,-1.03,1.92,,65.73,BHH,-1.32167,0.0495842,0.00501194,1.0225 PSD95pdz3_S371F,PSD95pdz3_371,PSD95pdz3,PSD95pdz3,P31016,1.0225,NO,371,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.86,-3.844,1.984,5.19744,,,,,17.1117,3.854,,87.71,HPB,-1.598,0.0758425,0.000847873,1.0225 PSD95pdz3_I389W,PSD95pdz3_389,PSD95pdz3,PSD95pdz3,P31016,1.02252,NO,389,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.628,-5.099,3.471,5.15116,,,,,14.8038,1.498,,87.71,HHH,-1.52167,0.0758425,0.00148097,1.02252 beta-lactamase_L137L,beta-lactamase_137,TEM-1,beta-lactamase,P62593,1.02253,NO,137,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.03,-1.03,,5.20117,,H,A,1.07,-0.38,0.674,,42.31,HHP,-1.58933,0.221079,0.00278599,1.02253 PSD95pdz3_L360Q,PSD95pdz3_360,PSD95pdz3,PSD95pdz3,P31016,1.02253,NO,360,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.431,-3.696,2.265,5.09284,,,,,14.2425,1.419,,86.88,HHP,-1.52667,0.0758425,0.000770471,1.02253 beta-lactamase_39_R59W,beta-lactamase_39_59,TEM-1,beta-lactamase_39,P62593,1.02254,NO,59,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.345,-5.421,4.076,,0.329,S,L,1.2,-0.09,1.806,,73.08,HBO,-2.24267,0.0495842,0.00318082,1.02254 beta-lactamase_625_A225I,beta-lactamase_625_225,TEM-1,beta-lactamase_625,P62593,1.02255,NO,225,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.845,-4.041,2.196,,1,T,B,0.46,-0.38,9.874,9.874,74.48,OHO,-1.39967,0.213352,0.00465057,1.02255 beta-lactamase_39_A235V,beta-lactamase_39_235,TEM-1,beta-lactamase_39,P62593,1.02257,NO,235,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.266,-2.665,1.399,,0.32,E,B,0.46,-0.86,1.344,,50,OHO,-0.89,0.0495842,0.00493474,1.02257 beta-lactamase_39_E238R,beta-lactamase_39_238,TEM-1,beta-lactamase_39,P62593,1.02257,NO,238,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.002,-3.465,1.463,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.0495842,0.00743256,1.02257 PSD95pdz3_S361T,PSD95pdz3_361,PSD95pdz3,PSD95pdz3,P31016,1.02257,NO,361,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.519,-2.653,1.134,4.8722,,,,,16.4533,,,,HPH,-1.47167,0.0758425,0.00055296,1.02257 beta-lactamase_156_L160H,beta-lactamase_156_160,TEM-1,beta-lactamase_156,P62593,1.02258,NO,160,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.977,-4.948,3.971,,0.022,,B,0.55,-0.6,1.095,,44.41,BHA,-0.936,0.111618,0.00193775,1.02258 beta-lactamase_625_I285A,beta-lactamase_625_285,TEM-1,beta-lactamase_625,P62593,1.02259,NO,285,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.213352,0.101555,1.02259 kka2_1:1_H8R,kka2_1:1_8,Kka2,kka2_1:1,P00552,1.0226,NO,8,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-2.759,-3.714,0.955,,,,,,,16.971,16.971,71.59,HBH,-2.25467,0.520039,0.00256422,1.0226 beta-lactamase_F17V,beta-lactamase_17,TEM-1,beta-lactamase,P62593,1.02261,NO,17,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-2.337,-2.52,0.183,,,,,,,2.192,,67.83,HHO,-2.17733,0.221079,0.00216499,1.02261 beta-lactamase_G39K,beta-lactamase_39,TEM-1,beta-lactamase,P62593,1.02261,NO,39,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.864,-2.703,0.839,5.35574,0.701,T,L,0.23,0.47,29.926,29.926,77.62,HOH,-1.53633,0.221079,0.00487611,1.02261 beta-lactamase_G90K,beta-lactamase_90,TEM-1,beta-lactamase,P62593,1.02261,NO,90,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-2.091,-3.514,1.423,5.51991,0.598,T,A,0.23,0.32,1.791,,77.62,HOB,-1.52633,0.221079,0.00490273,1.02261 beta-lactamase_H156A,beta-lactamase_156,TEM-1,beta-lactamase,P62593,1.02261,NO,156,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-3.156,-2.83,-0.326,6.00284,0.753,S,A,0.72,-0.6,6.456,6.456,77.62,ABH,-1.932,0.221079,0.00468596,1.02261 beta-lactamase_I171M,beta-lactamase_171,TEM-1,beta-lactamase,P62593,1.02261,NO,171,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-2.431,-4.454,2.023,5.22771,0.361,,B,1,0.53,1.66,,77.62,HHO,-1.55533,0.221079,0.00623355,1.02261 beta-lactamase_K32M,beta-lactamase_32,TEM-1,beta-lactamase,P62593,1.02261,NO,32,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.984,-4.613,2.629,5.55842,0.563,H,A,1.82,0.34,1.754,,73.08,HBA,-2.04233,0.221079,0.00401283,1.02261 beta-lactamase_L19H,beta-lactamase_19,TEM-1,beta-lactamase,P62593,1.02261,NO,19,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.682,-4.734,3.052,,,,,,,4.261,,93.01,OHO,-1.894,0.221079,0.00215974,1.02261 beta-lactamase_39_E108T,beta-lactamase_39_108,TEM-1,beta-lactamase_39,P62593,1.02262,NO,108,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.46,-3.526,2.066,,0.572,G,A,1.04,1.87,20.151,20.151,72.73,PAB,-1.437,0.0495842,0.00413372,1.02262 beta-lactamase_39_T126Y,beta-lactamase_39_126,TEM-1,beta-lactamase_39,P62593,1.02262,NO,126,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.122,-4.294,3.172,,0.05,H,A,0.22,-0.05,0.586,,44.41,HPH,-1.60467,0.0495842,0.00244552,1.02262 beta-lactamase_39_R118Y,beta-lactamase_39_118,TEM-1,beta-lactamase_39,P62593,1.02263,NO,118,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.413,-4.398,1.985,,0.457,H,A,1.2,1.39,3.961,,77.62,HBA,-1.785,0.0495842,0.00538794,1.02263 gb1_T244V,gb1_244,gb1,gb1,P06654,1.02263,NO,244,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.637,-1.661,0.024,,,,,,,0.202,,11.83,PPA,-1.92567,0.177985,0.00222755,1.02263 gb1_Y229H,gb1_229,gb1,gb1,P06654,1.02263,NO,229,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-1.282,-3.516,2.234,,,,,,,,,,PHB,-1.4915,0.177985,0.00366605,1.02263 beta-lactamase_39_R92T,beta-lactamase_39_92,TEM-1,beta-lactamase_39,P62593,1.02264,NO,92,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.718,-2.88,1.162,,0.479,E,B,1.2,1.36,0.389,,65.38,BBH,-1.50367,0.0495842,0.00429626,1.02264 kka2_1:8_A64G,kka2_1:8_64,Kka2,kka2_1:8,P00552,1.02267,NO,64,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.496,-2.776,1.28,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.100394,0.00705578,1.02267 kka2_1:8_A64G,kka2_1:8_64,Kka2,kka2_1:8,P00552,1.02267,NO,64,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.496,-2.776,1.28,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.100394,0.00705578,1.02267 kka2_1:8_R143S,kka2_1:8_143,Kka2,kka2_1:8,P00552,1.02267,NO,143,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.525,-3.022,0.497,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.100394,0.00662247,1.02267 kka2_1:8_R143S,kka2_1:8_143,Kka2,kka2_1:8,P00552,1.02267,NO,143,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.525,-3.022,0.497,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.100394,0.00662247,1.02267 beta-lactamase_39_R275E,beta-lactamase_39_275,TEM-1,beta-lactamase_39,P62593,1.02268,NO,275,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.0495842,0.0141984,1.02268 beta-lactamase_156_S283K,beta-lactamase_156_283,TEM-1,beta-lactamase_156,P62593,1.0227,NO,283,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.111618,0.0429138,1.0227 beta-lactamase_39_G154S,beta-lactamase_39_154,TEM-1,beta-lactamase_39,P62593,1.02271,NO,154,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.823,-3.197,2.374,,0.54,T,l,0.29,-0.56,1.151,,64.69,HOA,-1.635,0.0495842,0.00180205,1.02271 beta-lactamase_625_V29I,beta-lactamase_625_29,TEM-1,beta-lactamase_625,P62593,1.02271,NO,29,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-2.856,-3.928,1.072,,0.733,H,A,0.44,-0.78,1.931,,93.01,HHB,-2.24733,0.213352,0.00318969,1.02271 beta-lactamase_156_I93V,beta-lactamase_156_93,TEM-1,beta-lactamase_156,P62593,1.02273,NO,93,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.401,-1.692,0.291,,0.128,E,B,0.48,0.44,1.524,,67.83,BHB,-1.873,0.111618,0.00527066,1.02273 beta-lactamase_T193R,beta-lactamase_193,TEM-1,beta-lactamase,P62593,1.02274,NO,193,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.914,-4.014,2.1,5.67952,0.439,H,a,0.3,0.33,1.863,,63.99,HPO,-1.52133,0.221079,0.00482669,1.02274 beta-lactamase_39_F70E,beta-lactamase_39_70,TEM-1,beta-lactamase_39,P62593,1.02275,NO,70,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.169,-3.82,2.651,,,H,A,0.58,-1.34,1.14,,63.99,PHB,-0.980667,0.0495842,0.00193499,1.02275 beta-lactamase_39_T187S,beta-lactamase_39_187,TEM-1,beta-lactamase_39,P62593,1.02275,NO,187,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.401,-2.134,0.733,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.0495842,0.00491782,1.02275 beta-lactamase_156_L219W,beta-lactamase_156_219,TEM-1,beta-lactamase_156,P62593,1.02276,NO,219,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.313,-5.183,3.87,,,I,A,0.55,-0.51,2.321,,74.48,HHB,-1.21533,0.111618,0.00664345,1.02276 beta-lactamase_39_I244S,beta-lactamase_39_244,TEM-1,beta-lactamase_39,P62593,1.02276,NO,244,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.555,-3.602,2.047,,,E,B,0.48,-0.84,1.325,,77.62,OHH,-1.385,0.0495842,0.00605379,1.02276 beta-lactamase_39_R273H,beta-lactamase_39_273,TEM-1,beta-lactamase_39,P62593,1.02276,NO,273,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.314,-4.599,2.285,,0.564,H,A,1.2,1.57,2.163,,73.78,ABP,-1.841,0.0495842,0.0077952,1.02276 PSD95pdz3_G356S,PSD95pdz3_356,PSD95pdz3,PSD95pdz3,P31016,1.02276,NO,356,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.008,-2.842,1.834,4.8656,,,,,11.9575,,,,BOA,-1.22933,0.0758425,0.000623061,1.02276 beta-lactamase_39_I206Y,beta-lactamase_39_206,TEM-1,beta-lactamase_39,P62593,1.02277,NO,206,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-2.429,-4.278,1.849,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.0495842,0.00528934,1.02277 gb1_V247I,gb1_247,gb1,gb1,P06654,1.02277,NO,247,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.711,-2.08,0.369,,,,,,,0.805,,44.87,HHA,-1.485,0.177985,0.00435373,1.02277 beta-lactamase_156_A211L,beta-lactamase_156_211,TEM-1,beta-lactamase_156,P62593,1.02278,NO,211,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.896,-3.595,1.699,,0.369,T,A,0.46,-0.69,8.527,8.527,77.62,AHA,-1.94633,0.111618,0.00648183,1.02278 PSD95pdz3_L360E,PSD95pdz3_360,PSD95pdz3,PSD95pdz3,P31016,1.02278,NO,360,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.431,-3.571,2.14,5.09284,,,,,14.2425,1.419,,86.88,HHP,-1.52667,0.0758425,0.000770471,1.02278 beta-lactamase_0_G216D,beta-lactamase_0_216,TEM-1,beta-lactamase_0,P62593,1.02279,NO,216,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.477,-1.722,0.245,,0.437,I,A,0.29,-0.58,0.834,,74.48,HOO,-1.68067,0.0500837,0.00639568,1.02279 beta-lactamase_156_T186M,beta-lactamase_156_186,TEM-1,beta-lactamase_156,P62593,1.02279,NO,186,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.522,-3.419,0.897,,0.396,H,A,0.22,-0.28,16.606,16.606,77.62,HPP,-1.77633,0.111618,0.00485034,1.02279 beta-lactamase_0_A77I,beta-lactamase_0_77,TEM-1,beta-lactamase_0,P62593,1.0228,NO,77,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.234,-3.583,2.349,,0.039,H,A,0.46,-0.56,2.591,,64.34,OHH,-1.294,0.0500837,0.00282362,1.0228 beta-lactamase_156_I93L,beta-lactamase_156_93,TEM-1,beta-lactamase_156,P62593,1.02281,NO,93,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.401,-2.05,0.649,,0.128,E,B,0.48,0.44,1.524,,67.83,BHB,-1.873,0.111618,0.00527066,1.02281 beta-lactamase_156_L219D,beta-lactamase_156_219,TEM-1,beta-lactamase_156,P62593,1.02281,NO,219,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.313,-4.126,2.813,,,I,A,0.55,-0.51,2.321,,74.48,HHB,-1.21533,0.111618,0.00664345,1.02281 beta-lactamase_625_I258C,beta-lactamase_625_258,TEM-1,beta-lactamase_625,P62593,1.02282,NO,258,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.213352,0.007931,1.02282 beta-lactamase_T193G,beta-lactamase_193,TEM-1,beta-lactamase,P62593,1.02282,NO,193,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.914,-3.548,1.634,5.67952,0.439,H,a,0.3,0.33,1.863,,63.99,HPO,-1.52133,0.221079,0.00482669,1.02282 beta-lactamase_156_V117I,beta-lactamase_156_117,TEM-1,beta-lactamase_156,P62593,1.02284,NO,117,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.53,-1.923,0.393,,,H,A,0.44,-0.34,1.182,,65.03,PHB,-1.741,0.111618,0.00467906,1.02284 beta-lactamase_2500_K190G,beta-lactamase_2500_190,TEM-1,beta-lactamase_2500,P62593,1.02284,NO,190,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.994,-3.44,1.446,,0.371,H,A,2.34,0.16,29.753,29.753,77.62,BBH,-1.64167,0.361275,0.00574527,1.02284 beta-lactamase_2500_Q88D,beta-lactamase_2500_88,TEM-1,beta-lactamase_2500,P62593,1.02285,NO,88,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.086,-2.035,-0.051,,0.807,,B,0.64,2.03,1.84,,77.62,APH,-1.53433,0.361275,0.00504167,1.02285 beta-lactamase_625_R118S,beta-lactamase_625_118,TEM-1,beta-lactamase_625,P62593,1.02285,NO,118,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.413,-2.394,-0.019,,0.457,H,A,1.2,1.39,2.144,,77.62,HBA,-1.785,0.213352,0.00538794,1.02285 beta-lactamase_0_A278M,beta-lactamase_0_278,TEM-1,beta-lactamase_0,P62593,1.02286,NO,278,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.348,,,,0.015,H,A,0.48,-0.85,4.624,,63.29,HHA,-1.41833,0.0500837,0.0310297,1.02286 beta-lactamase_156_D212P,beta-lactamase_156_212,TEM-1,beta-lactamase_156,P62593,1.02287,NO,212,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.624,-3.916,2.292,,0.037,,b,0.75,-0.58,20.222,20.222,74.48,HAB,-1.77667,0.111618,0.00644302,1.02287 beta-lactamase_156_T138S,beta-lactamase_156_138,TEM-1,beta-lactamase_156,P62593,1.02287,NO,138,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.506,-2.455,-0.051,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.111618,0.00487868,1.02287 beta-lactamase_39_R41N,beta-lactamase_39_41,TEM-1,beta-lactamase_39,P62593,1.02288,NO,41,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-0.942,-3.445,2.503,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.0495842,0.00123327,1.02288 beta-lactamase_39_A235G,beta-lactamase_39_235,TEM-1,beta-lactamase_39,P62593,1.0229,NO,235,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.266,-2.075,0.809,,0.32,E,B,0.46,-0.86,1.344,,50,OHO,-0.89,0.0495842,0.00493474,1.0229 beta-lactamase_625_E102Y,beta-lactamase_625_102,TEM-1,beta-lactamase_625,P62593,1.0229,NO,102,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.118,-4.321,2.203,,0.722,S,B,1.04,1.82,1.336,,73.08,HAH,-1.581,0.213352,0.00486633,1.0229 kka2_1:8_W24M,kka2_1:8_24,Kka2,kka2_1:8,P00552,1.0229,NO,24,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-1.779,-3.383,1.604,,0.477,E,B,1.51,-0.21,2.503,,56.06,AHH,-2.24467,0.100394,0.00631564,1.0229 kka2_1:8_W24M,kka2_1:8_24,Kka2,kka2_1:8,P00552,1.0229,NO,24,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-1.779,-3.383,1.604,,0.477,E,B,1.51,-0.21,2.503,,56.06,AHH,-2.24467,0.100394,0.00631564,1.0229 PSD95pdz3_Q391R,PSD95pdz3_391,PSD95pdz3,PSD95pdz3,P31016,1.0229,NO,391,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-1.699,-2.94,1.241,5.50275,,,,,12.6589,,,,HPH,-1.481,0.0758425,0.000990786,1.0229 gb1_A252G,gb1_252,gb1,gb1,P06654,1.02291,NO,252,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.175,-2.644,1.469,,,,,,,,,,PHA,-1.55967,0.177985,0.00125598,1.02291 beta-lactamase_156_E61M,beta-lactamase_156_61,TEM-1,beta-lactamase_156,P62593,1.02292,NO,61,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.115,-4.881,2.766,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.111618,0.00440955,1.02292 beta-lactamase_39_P25E,beta-lactamase_39_25,TEM-1,beta-lactamase_39,P62593,1.02294,NO,25,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.526,-2.543,1.017,,0.624,H,A,0.52,0.14,1.157,,73.08,BOA,-2.15367,0.0495842,0.00347571,1.02294 PSD95pdz3_L349K,PSD95pdz3_349,PSD95pdz3,PSD95pdz3,P31016,1.02294,NO,349,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.347,-3.364,2.017,5.14696,,,,,24.6438,,,,AHP,-1.37667,0.0758425,0.00071841,1.02294 beta-lactamase_156_R189K,beta-lactamase_156_189,TEM-1,beta-lactamase_156,P62593,1.02295,NO,189,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.844,-2.391,0.547,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.111618,0.0050699,1.02295 kka2_1:2_A35V,kka2_1:2_35,Kka2,kka2_1:2,P00552,1.02296,NO,35,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.127,-3.696,1.569,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.295029,0.00630016,1.02296 beta-lactamase_625_E108N,beta-lactamase_625_108,TEM-1,beta-lactamase_625,P62593,1.02297,NO,108,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.46,-3.593,2.133,,0.572,G,A,1.04,1.87,20.151,20.151,72.73,PAB,-1.437,0.213352,0.00413372,1.02297 beta-lactamase_0_M209W,beta-lactamase_0_209,TEM-1,beta-lactamase_0,P62593,1.02298,NO,209,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.442,-4.979,3.537,,,H,A,0.55,-0.97,3.876,,64.69,HHA,-1.52633,0.0500837,0.00625021,1.02298 beta-lactamase_39_E195S,beta-lactamase_39_195,TEM-1,beta-lactamase_39,P62593,1.02299,NO,195,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.186,-2.512,0.326,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.0495842,0.00496565,1.02299 PSD95pdz3_K393Q,PSD95pdz3_393,PSD95pdz3,PSD95pdz3,P31016,1.023,NO,393,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.416,-3.131,1.715,5.42682,,,,,22.0122,,,,HBO,-1.4265,0.0758425,0.000879298,1.023 beta-lactamase_156_E26R,beta-lactamase_156_26,TEM-1,beta-lactamase_156,P62593,1.02302,NO,26,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.454,-2.433,-0.021,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.111618,0.00297948,1.02302 PSD95pdz3_I377S,PSD95pdz3_377,PSD95pdz3,PSD95pdz3,P31016,1.02303,NO,377,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.873,-3.305,1.432,4.9532,,,,,19.185,2.364,,87.71,HHH,-1.49567,0.0758425,0.000795475,1.02303 beta-lactamase_0_T178Q,beta-lactamase_0_178,TEM-1,beta-lactamase_0,P62593,1.02304,NO,178,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-0.791,-3.899,3.108,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.0500837,0.000684366,1.02304 beta-lactamase_2500_T186Y,beta-lactamase_2500_186,TEM-1,beta-lactamase_2500,P62593,1.02304,NO,186,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.522,-4.364,1.842,,0.396,H,A,0.22,-0.28,2.144,,77.62,HPP,-1.77633,0.361275,0.00485034,1.02304 kka2_1:2_L53M,kka2_1:2_53,Kka2,kka2_1:2,P00552,1.02304,NO,53,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-2.681,-3.617,0.936,,0.569,E,B,0.55,0.8,19.536,19.536,71.59,AHP,-2.47433,0.295029,0.00671168,1.02304 beta-lactamase_39_T186R,beta-lactamase_39_186,TEM-1,beta-lactamase_39,P62593,1.02305,NO,186,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.522,-2.819,0.297,,0.396,H,A,0.22,-0.28,0.515,,77.62,HPP,-1.77633,0.0495842,0.00485034,1.02305 beta-lactamase_H151H,beta-lactamase_151,TEM-1,beta-lactamase,P62593,1.02305,NO,151,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-2.96,-2.96,,5.47408,0.594,H,A,0.35,0.1,1.843,,77.62,HBP,-2.34767,0.221079,0.00216946,1.02305 gb1_A274E,gb1_274,gb1,gb1,P06654,1.02305,NO,274,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.728,-1.764,0.036,,,,,,,4.162,4.162,11.83,AHP,-1.81767,0.177985,0.0068419,1.02305 beta-lactamase_0_K232L,beta-lactamase_0_232,TEM-1,beta-lactamase_0,P62593,1.02307,NO,232,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.012,-3.401,2.389,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.0500837,0.00313441,1.02307 beta-lactamase_156_T27A,beta-lactamase_156_27,TEM-1,beta-lactamase_156,P62593,1.02308,NO,27,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.905,-2.5,0.595,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.111618,0.00306559,1.02308 kka2_1:8_E231I,kka2_1:8_231,Kka2,kka2_1:8,P00552,1.02312,NO,231,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.002,-3.963,1.961,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.100394,0.00732383,1.02312 kka2_1:8_E231I,kka2_1:8_231,Kka2,kka2_1:8,P00552,1.02312,NO,231,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.002,-3.963,1.961,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.100394,0.00732383,1.02312 kka2_1:8_I254K,kka2_1:8_254,Kka2,kka2_1:8,P00552,1.02312,NO,254,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.933,-3.795,1.862,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.100394,0.0132375,1.02312 kka2_1:8_I254K,kka2_1:8_254,Kka2,kka2_1:8,P00552,1.02312,NO,254,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.933,-3.795,1.862,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.100394,0.0132375,1.02312 beta-lactamase_625_I285L,beta-lactamase_625_285,TEM-1,beta-lactamase_625,P62593,1.02315,NO,285,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.213352,0.101555,1.02315 PSD95pdz3_V362S,PSD95pdz3_362,PSD95pdz3,PSD95pdz3,P31016,1.02315,NO,362,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.465,-3.292,1.827,4.99436,,,,,19.6443,,,,PHP,-1.46467,0.0758425,0.000538527,1.02315 beta-lactamase_0_Y44R,beta-lactamase_0_44,TEM-1,beta-lactamase_0,P62593,1.02316,NO,44,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-2.547,-4.123,1.576,,,E,B,0.21,-0.45,1.751,,73.78,OHH,-1.86267,0.0500837,0.00426364,1.02316 beta-lactamase_39_R118I,beta-lactamase_39_118,TEM-1,beta-lactamase_39,P62593,1.02316,NO,118,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.413,-3.968,1.555,,0.457,H,A,1.2,1.39,3.961,,77.62,HBA,-1.785,0.0495842,0.00538794,1.02316 beta-lactamase_625_F58R,beta-lactamase_625_58,TEM-1,beta-lactamase_625,P62593,1.02316,NO,58,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-2.914,-2.758,-0.156,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.213352,0.00523369,1.02316 beta-lactamase_156_I261F,beta-lactamase_156_261,TEM-1,beta-lactamase_156,P62593,1.02318,NO,261,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.111618,0.0123091,1.02318 PSD95pdz3_F340H,PSD95pdz3_340,PSD95pdz3,PSD95pdz3,P31016,1.02319,NO,340,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.524,-4.137,2.613,5.79283,,,,,11.8045,,,,PHH,-1.55767,0.0758425,0.000836987,1.02319 PSD95pdz3_I314R,PSD95pdz3_314,PSD95pdz3,PSD95pdz3,P31016,1.02319,NO,314,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.628,-3.935,2.307,5.39919,,,,,15.7775,0.397,,81.35,BHH,-1.61167,0.0758425,0.0012606,1.02319 beta-lactamase_625_R202V,beta-lactamase_625_202,TEM-1,beta-lactamase_625,P62593,1.0232,NO,202,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.292,-3.679,2.387,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.213352,0.00321899,1.0232 beta-lactamase_156_L284F,beta-lactamase_156_284,TEM-1,beta-lactamase_156,P62593,1.02321,NO,284,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.111618,0.0686156,1.02321 beta-lactamase_D36L,beta-lactamase_36,TEM-1,beta-lactamase,P62593,1.02322,NO,36,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.732,-3.628,0.896,5.39764,0.555,H,A,0.11,1.17,13.689,13.689,77.62,AAP,-1.91167,0.221079,0.00476483,1.02322 beta-lactamase_R238N,beta-lactamase_238,TEM-1,beta-lactamase,P62593,1.02322,NO,238,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.002,-2.276,0.274,5.87663,0.564,T,L,0.45,1.09,4.195,,72.73,ABO,-1.62633,0.221079,0.00743256,1.02322 beta-lactamase_0_K213M,beta-lactamase_0_213,TEM-1,beta-lactamase_0,P62593,1.02323,NO,213,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.81,-4.653,2.843,,0.67,,A,2.34,0.29,3.015,,67.83,ABH,-1.57767,0.0500837,0.00610411,1.02323 beta-lactamase_156_E87M,beta-lactamase_156_87,TEM-1,beta-lactamase_156,P62593,1.02323,NO,87,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.421,-4.574,3.153,,0.048,,B,1.04,0.92,1.754,,64.69,PAP,-1.969,0.111618,0.00337888,1.02323 beta-lactamase_156_A170K,beta-lactamase_156_170,TEM-1,beta-lactamase_156,P62593,1.02324,NO,170,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.237,-3.643,2.406,,0.126,,L,0.46,-0.35,3.7,,64.69,AHH,-1.63267,0.111618,0.00431903,1.02324 beta-lactamase_39_R220V,beta-lactamase_39_220,TEM-1,beta-lactamase_39,P62593,1.02324,NO,220,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-0.942,-3.675,2.733,,0.295,I,A,1.2,-0.76,1.596,,74.48,HBP,-1.33633,0.0495842,0.00232421,1.02324 beta-lactamase_156_R118W,beta-lactamase_156_118,TEM-1,beta-lactamase_156,P62593,1.02325,NO,118,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.413,-5.439,3.026,,0.457,H,A,1.2,1.39,2.231,,77.62,HBA,-1.785,0.111618,0.00538794,1.02325 beta-lactamase_625_T112N,beta-lactamase_625_112,TEM-1,beta-lactamase_625,P62593,1.02326,NO,112,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.186,-2.739,0.553,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.213352,0.00531334,1.02326 PSD95pdz3_G335T,PSD95pdz3_335,PSD95pdz3,PSD95pdz3,P31016,1.02326,NO,335,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.008,-3.328,2.32,4.76223,,,,,22.4225,,,,AOH,-1.34733,0.0758425,0.000900493,1.02326 beta-lactamase_156_T112K,beta-lactamase_156_112,TEM-1,beta-lactamase_156,P62593,1.02327,NO,112,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.186,-2.704,0.518,,0.921,T,A,0.22,1.06,2.87,,73.78,HPA,-1.925,0.111618,0.00531334,1.02327 kka2_1:4_G88E,kka2_1:4_88,Kka2,kka2_1:4,P00552,1.02327,NO,88,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.689,-2.331,0.642,,0.54,S,l,0.29,1.51,7.899,,65.53,HOB,-1.718,0.168804,0.00685559,1.02327 beta-lactamase_156_A225Y,beta-lactamase_156_225,TEM-1,beta-lactamase_156,P62593,1.02328,NO,225,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.845,-4.327,2.482,,1,T,B,0.46,-0.38,11.722,11.722,74.48,OHO,-1.39967,0.111618,0.00465057,1.02328 beta-lactamase_2500_L284I,beta-lactamase_2500_284,TEM-1,beta-lactamase_2500,P62593,1.02328,NO,284,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.361275,0.0686156,1.02328 beta-lactamase_S281A,beta-lactamase_281,TEM-1,beta-lactamase,P62593,1.02328,NO,281,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.247,-1.374,-0.873,4.73591,0.128,H,A,0.25,-0.26,2.144,,77.62,HPH,-1.847,0.221079,0.0406482,1.02328 beta-lactamase_2500_E272A,beta-lactamase_2500_272,TEM-1,beta-lactamase_2500,P62593,1.02331,NO,272,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.361275,0.00545371,1.02331 beta-lactamase_2500_T186H,beta-lactamase_2500_186,TEM-1,beta-lactamase_2500,P62593,1.02331,NO,186,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.522,-4.717,2.195,,0.396,H,A,0.22,-0.28,2.144,,77.62,HPP,-1.77633,0.361275,0.00485034,1.02331 beta-lactamase_39_E195K,beta-lactamase_39_195,TEM-1,beta-lactamase_39,P62593,1.02332,NO,195,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.186,-2.529,0.343,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.0495842,0.00496565,1.02332 gb1_T243S,gb1_243,gb1,gb1,P06654,1.02333,NO,243,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.415,-2.747,1.332,,,,,,,1.083,,37.28,PPP,-1.43233,0.177985,0.00308687,1.02333 beta-lactamase_156_H287Q,beta-lactamase_156_287,TEM-1,beta-lactamase_156,P62593,1.02335,NO,287,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,,,,,,,,,,,,,BBH,-1.111,0.111618,,1.02335 beta-lactamase_625_E108A,beta-lactamase_625_108,TEM-1,beta-lactamase_625,P62593,1.02335,NO,108,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.46,-2.613,1.153,,0.572,G,A,1.04,1.87,20.151,20.151,72.73,PAB,-1.437,0.213352,0.00413372,1.02335 beta-lactamase_156_M270K,beta-lactamase_156_270,TEM-1,beta-lactamase_156,P62593,1.02336,NO,270,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.111618,0.00767762,1.02336 beta-lactamase_625_H110S,beta-lactamase_625_110,TEM-1,beta-lactamase_625,P62593,1.02336,NO,110,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-1.706,-3.537,1.831,,0.341,G,a,0.17,1.08,31.31,31.31,64.69,BBH,-1.73333,0.213352,0.00441499,1.02336 kka2_1:8_L158N,kka2_1:8_158,Kka2,kka2_1:8,P00552,1.02336,NO,158,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.947,-4.203,2.256,,0.095,.,B,0.55,0.77,1.607,,63.64,AHA,-1.25333,0.100394,0.00529068,1.02336 kka2_1:8_L158N,kka2_1:8_158,Kka2,kka2_1:8,P00552,1.02336,NO,158,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.947,-4.203,2.256,,0.095,.,B,0.55,0.77,1.607,,63.64,AHA,-1.25333,0.100394,0.00529068,1.02336 beta-lactamase_0_L199I,beta-lactamase_0_199,TEM-1,beta-lactamase_0,P62593,1.02338,NO,199,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-2.942,-3.16,0.218,,0.832,H,A,0.55,0.42,10.85,10.85,77.62,PHH,-2.32933,0.0500837,0.0048649,1.02338 beta-lactamase_39_A235E,beta-lactamase_39_235,TEM-1,beta-lactamase_39,P62593,1.02338,NO,235,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.266,-3.558,2.292,,0.32,E,B,0.46,-0.86,1.344,,50,OHO,-0.89,0.0495842,0.00493474,1.02338 beta-lactamase_625_T138E,beta-lactamase_625_138,TEM-1,beta-lactamase_625,P62593,1.02338,NO,138,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.506,-2.168,-0.338,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.213352,0.00487868,1.02338 beta-lactamase_625_A278Q,beta-lactamase_625_278,TEM-1,beta-lactamase_625,P62593,1.02339,NO,278,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.213352,0.0310297,1.02339 beta-lactamase_156_I285F,beta-lactamase_156_285,TEM-1,beta-lactamase_156,P62593,1.0234,NO,285,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.111618,0.101555,1.0234 beta-lactamase_39_E272W,beta-lactamase_39_272,TEM-1,beta-lactamase_39,P62593,1.0234,NO,272,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.127,,,,0.081,H,A,0.43,-0.97,12.983,12.983,63.64,AAB,-1.56333,0.0495842,0.00545371,1.0234 beta-lactamase_625_I285M,beta-lactamase_625_285,TEM-1,beta-lactamase_625,P62593,1.02341,NO,285,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.213352,0.101555,1.02341 beta-lactamase_625_E272Y,beta-lactamase_625_272,TEM-1,beta-lactamase_625,P62593,1.02342,NO,272,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.213352,0.00545371,1.02342 beta-lactamase_625_R159Q,beta-lactamase_625_159,TEM-1,beta-lactamase_625,P62593,1.02343,NO,159,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-0.94,-3.498,2.558,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.213352,0.00108472,1.02343 beta-lactamase_R118E,beta-lactamase_118,TEM-1,beta-lactamase,P62593,1.02343,NO,118,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.413,-2.454,0.041,5.8227,0.457,H,A,0.68,1.39,2.144,,77.62,HBA,-1.785,0.221079,0.00538794,1.02343 kka2_1:4_V97I,kka2_1:4_97,Kka2,kka2_1:4,P00552,1.02343,NO,97,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.453,-2.403,0.95,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.168804,0.00737869,1.02343 WW_domain_S183T,WW_domain_183,Yap65,WW_domain,P46937,1.02343,NO,183,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.95,-2.388,0.438,5.35576,,,,,,1.594,,83.93,PPP,-1.48733,0.153962,0.00445513,1.02343 beta-lactamase_156_I140F,beta-lactamase_156_140,TEM-1,beta-lactamase_156,P62593,1.02345,NO,140,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.733,-2.91,1.177,,0.128,H,A,0.48,0.41,1.16,,73.08,PHO,-1.48733,0.111618,0.00597777,1.02345 beta-lactamase_39_R159D,beta-lactamase_39_159,TEM-1,beta-lactamase_39,P62593,1.02345,NO,159,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-0.94,-3.691,2.751,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.0495842,0.00108472,1.02345 beta-lactamase_G90E,beta-lactamase_90,TEM-1,beta-lactamase,P62593,1.02345,NO,90,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-2.091,-2.175,0.084,5.51991,0.598,T,A,0.23,0.32,1.791,,77.62,HOB,-1.52633,0.221079,0.00490273,1.02345 beta-lactamase_L196S,beta-lactamase_196,TEM-1,beta-lactamase,P62593,1.02345,NO,196,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-2.478,-2.752,0.274,,0.518,S,A,0.55,1.35,,,77.62,AHH,-1.839,0.221079,0.00512144,1.02345 beta-lactamase_625_L223V,beta-lactamase_625_223,TEM-1,beta-lactamase_625,P62593,1.02346,NO,223,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.055,-2.195,1.14,,0.27,,B,0.55,0.09,1.633,,74.48,HHO,-1.35033,0.213352,0.00372793,1.02346 beta-lactamase_156_E87I,beta-lactamase_156_87,TEM-1,beta-lactamase_156,P62593,1.02347,NO,87,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.421,-3.687,2.266,,0.048,,B,1.04,0.92,1.754,,64.69,PAP,-1.969,0.111618,0.00337888,1.02347 beta-lactamase_625_E26Q,beta-lactamase_625_26,TEM-1,beta-lactamase_625,P62593,1.02347,NO,26,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.454,-2.296,-0.158,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.213352,0.00297948,1.02347 beta-lactamase_625_E26R,beta-lactamase_625_26,TEM-1,beta-lactamase_625,P62593,1.02347,NO,26,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.454,-2.433,-0.021,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.213352,0.00297948,1.02347 beta-lactamase_0_M270Q,beta-lactamase_0_270,TEM-1,beta-lactamase_0,P62593,1.02348,NO,270,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.0500837,0.00767762,1.02348 beta-lactamase_156_Q203F,beta-lactamase_156_203,TEM-1,beta-lactamase_156,P62593,1.02352,NO,203,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.168,-4.379,2.211,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.111618,0.00631514,1.02352 beta-lactamase_156_I261Y,beta-lactamase_156_261,TEM-1,beta-lactamase_156,P62593,1.02353,NO,261,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.111618,0.0123091,1.02353 beta-lactamase_0_L205E,beta-lactamase_0_205,TEM-1,beta-lactamase_0,P62593,1.02354,NO,205,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.922,-3.908,2.986,,,H,A,0.55,-0.46,1.065,,42.31,PHH,-1.57767,0.0500837,0.00255802,1.02354 beta-lactamase_156_T131H,beta-lactamase_156_131,TEM-1,beta-lactamase_156,P62593,1.02354,NO,131,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.328,-4.721,3.393,,,H,A,0.22,-0.69,2.031,,67.48,PPH,-1.00867,0.111618,0.00345886,1.02354 beta-lactamase_2500_H151N,beta-lactamase_2500_151,TEM-1,beta-lactamase_2500,P62593,1.02354,NO,151,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-2.96,-3.49,0.53,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.361275,0.00216946,1.02354 beta-lactamase_2500_T186N,beta-lactamase_2500_186,TEM-1,beta-lactamase_2500,P62593,1.02354,NO,186,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.522,-3.756,1.234,,0.396,H,A,0.22,-0.28,2.144,,77.62,HPP,-1.77633,0.361275,0.00485034,1.02354 beta-lactamase_625_A183N,beta-lactamase_625_183,TEM-1,beta-lactamase_625,P62593,1.02354,NO,183,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.231,-2.504,1.273,,0.155,H,A,0.46,-0.91,23.859,23.859,77.62,HHH,-1.53367,0.213352,0.00296631,1.02354 beta-lactamase_625_G39M,beta-lactamase_625_39,TEM-1,beta-lactamase_625,P62593,1.02355,NO,39,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.864,-4.879,3.015,,0.701,T,L,0.29,0.47,29.926,29.926,77.62,HOH,-1.53633,0.213352,0.00487611,1.02355 beta-lactamase_156_E108Y,beta-lactamase_156_108,TEM-1,beta-lactamase_156,P62593,1.02357,NO,108,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.46,-4.347,2.887,,0.572,G,A,1.04,1.87,8.602,8.602,72.73,PAB,-1.437,0.111618,0.00413372,1.02357 beta-lactamase_625_I54T,beta-lactamase_625_54,TEM-1,beta-lactamase_625,P62593,1.02357,NO,54,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-2.838,-2.043,-0.795,,0.669,E,B,0.48,-0.14,3.946,,73.78,BHH,-2.337,0.213352,0.00403589,1.02357 beta-lactamase_156_I45Y,beta-lactamase_156_45,TEM-1,beta-lactamase_156,P62593,1.02359,NO,45,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-2.421,-2.914,0.493,,,E,B,0.48,-0.3,2.256,,77.62,HHA,-2.30267,0.111618,0.00452842,1.02359 beta-lactamase_39_E108V,beta-lactamase_39_108,TEM-1,beta-lactamase_39,P62593,1.02359,NO,108,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.46,-3.706,2.246,,0.572,G,A,1.04,1.87,20.151,20.151,72.73,PAB,-1.437,0.0495842,0.00413372,1.02359 beta-lactamase_39_P250Y,beta-lactamase_39_250,TEM-1,beta-lactamase_39,P62593,1.02359,NO,250,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.0495842,0.00550899,1.02359 beta-lactamase_D33R,beta-lactamase_33,TEM-1,beta-lactamase,P62593,1.02359,NO,33,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.321,-2.617,0.296,5.05203,0.366,H,A,0.23,0.33,2.032,,77.62,BAH,-2.12133,0.221079,0.00435556,1.02359 beta-lactamase_L199E,beta-lactamase_199,TEM-1,beta-lactamase,P62593,1.02359,NO,199,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-2.942,-2.604,-0.338,5.57712,0.832,H,A,0.82,0.42,15.302,15.302,77.62,PHH,-2.32933,0.221079,0.0048649,1.02359 beta-lactamase_L55M,beta-lactamase_55,TEM-1,beta-lactamase,P62593,1.02359,NO,55,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.86,-4.329,2.469,,0.372,E,A,1.07,-0.36,1.423,,63.99,HHA,-2.247,0.221079,0.00403741,1.02359 beta-lactamase_Q203E,beta-lactamase_203,TEM-1,beta-lactamase,P62593,1.02359,NO,203,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.168,-2.449,0.281,5.65296,0.47,H,A,0.12,-0.38,1.66,,65.38,BPP,-1.614,0.221079,0.00631514,1.02359 gb1_T251A,gb1_251,gb1,gb1,P06654,1.0236,NO,251,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.794,-2.797,1.003,,,,,,,3.514,3.514,37.28,HPH,-1.56067,0.177985,0.00232932,1.0236 kka2_1:4_R253H,kka2_1:4_253,Kka2,kka2_1:4,P00552,1.02361,NO,253,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.356,-4.521,3.165,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.168804,0.0144195,1.02361 beta-lactamase_0_N173A,beta-lactamase_0_173,TEM-1,beta-lactamase_0,P62593,1.02362,NO,173,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-2.663,-2.432,-0.231,,1.044,T,l,0.61,1.25,1.133,,77.62,OPA,-1.46633,0.0500837,0.0033769,1.02362 PSD95pdz3_Q374L,PSD95pdz3_374,PSD95pdz3,PSD95pdz3,P31016,1.02363,NO,374,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-1.699,-3.04,1.341,5.38825,,,,,17.3289,,,,APH,-1.47,0.0758425,0.000372298,1.02363 beta-lactamase_2500_T186M,beta-lactamase_2500_186,TEM-1,beta-lactamase_2500,P62593,1.02364,NO,186,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.522,-3.419,0.897,,0.396,H,A,0.22,-0.28,2.144,,77.62,HPP,-1.77633,0.361275,0.00485034,1.02364 kka2_1:2_A168S,kka2_1:2_168,Kka2,kka2_1:2,P00552,1.02364,NO,168,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.989,-2.65,0.661,,0.67,H,A,0.46,0.15,25.546,25.546,64.39,OHA,-2.12933,0.295029,0.00806773,1.02364 beta-lactamase_156_P65N,beta-lactamase_156_65,TEM-1,beta-lactamase_156,P62593,1.02366,NO,65,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.894,-3.952,3.058,,0.098,E,B,0.52,-0.62,0.623,,40.56,HOH,-1.03233,0.111618,0.00152776,1.02366 beta-lactamase_625_E195M,beta-lactamase_625_195,TEM-1,beta-lactamase_625,P62593,1.02366,NO,195,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.186,-4.856,2.67,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.213352,0.00496565,1.02366 beta-lactamase_625_D36M,beta-lactamase_625_36,TEM-1,beta-lactamase_625,P62593,1.02367,NO,36,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.732,-4.763,2.031,,0.555,H,A,0.75,1.17,2.26,,77.62,AAP,-1.91167,0.213352,0.00476483,1.02367 beta-lactamase_156_I244C,beta-lactamase_156_244,TEM-1,beta-lactamase_156,P62593,1.02368,NO,244,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.555,-4.712,3.157,,,E,B,0.48,-0.84,1.325,,77.62,OHH,-1.385,0.111618,0.00605379,1.02368 beta-lactamase_625_P255T,beta-lactamase_625_255,TEM-1,beta-lactamase_625,P62593,1.02368,NO,255,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.213352,0.00499612,1.02368 kka2_1:8_E111F,kka2_1:8_111,Kka2,kka2_1:8,P00552,1.02368,NO,111,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.28,-4.475,2.195,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.100394,0.00746789,1.02368 kka2_1:8_E111F,kka2_1:8_111,Kka2,kka2_1:8,P00552,1.02368,NO,111,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.28,-4.475,2.195,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.100394,0.00746789,1.02368 beta-lactamase_625_V29N,beta-lactamase_625_29,TEM-1,beta-lactamase_625,P62593,1.02372,NO,29,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-2.856,-2.832,-0.024,,0.733,H,A,0.44,-0.78,1.931,,93.01,HHB,-2.24733,0.213352,0.00318969,1.02372 beta-lactamase_156_A215E,beta-lactamase_156_215,TEM-1,beta-lactamase_156,P62593,1.02374,NO,215,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.503,-3.531,2.028,,,,a,0.46,-0.93,3.583,,74.48,HHO,-1.42633,0.111618,0.00544007,1.02374 beta-lactamase_39_T112A,beta-lactamase_39_112,TEM-1,beta-lactamase_39,P62593,1.02374,NO,112,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.186,-1.933,-0.253,,0.921,T,A,0.22,1.06,2.87,,73.78,HPA,-1.925,0.0495842,0.00531334,1.02374 beta-lactamase_625_E26T,beta-lactamase_625_26,TEM-1,beta-lactamase_625,P62593,1.02375,NO,26,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.454,-2.753,0.299,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.213352,0.00297948,1.02375 beta-lactamase_A16V,beta-lactamase_16,TEM-1,beta-lactamase,P62593,1.02375,NO,16,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,,-2.642,0.707,,,,,,,,,,HHH,,0.221079,0.00245392,1.02375 beta-lactamase_625_K144I,beta-lactamase_625_144,TEM-1,beta-lactamase_625,P62593,1.02376,NO,144,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-2.388,-4.014,1.626,,0.863,H,A,2.34,1.27,2.313,,77.62,OBA,-1.904,0.213352,0.00481141,1.02376 beta-lactamase_T131G,beta-lactamase_131,TEM-1,beta-lactamase,P62593,1.02377,NO,131,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.328,-3.298,1.97,5.0548,,H,A,0.53,-0.69,3.306,,67.48,PPH,-1.00867,0.221079,0.00345886,1.02377 beta-lactamase_0_T116R,beta-lactamase_0_116,TEM-1,beta-lactamase_0,P62593,1.02379,NO,116,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.28,-2.627,1.347,,0.115,E,B,0.22,-0.12,1.356,,67.48,HPH,-1.39967,0.0500837,0.00336175,1.02379 beta-lactamase_39_H151I,beta-lactamase_39_151,TEM-1,beta-lactamase_39,P62593,1.02379,NO,151,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-2.96,-4.091,1.131,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.0495842,0.00216946,1.02379 beta-lactamase_625_E87V,beta-lactamase_625_87,TEM-1,beta-lactamase_625,P62593,1.02381,NO,87,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.421,-2.385,0.964,,0.048,,B,1.04,0.92,17.923,17.923,64.69,PAP,-1.969,0.213352,0.00337888,1.02381 kka2_1:8_F256A,kka2_1:8_256,Kka2,kka2_1:8,P00552,1.02381,NO,256,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.49,-3.439,1.949,,,H,A,1.62,-0.78,1.713,,53.03,HHH,-1.423,0.100394,0.0132841,1.02381 kka2_1:8_F256A,kka2_1:8_256,Kka2,kka2_1:8,P00552,1.02381,NO,256,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.49,-3.439,1.949,,,H,A,1.62,-0.78,1.713,,53.03,HHH,-1.423,0.100394,0.0132841,1.02381 beta-lactamase_39_F58S,beta-lactamase_39_58,TEM-1,beta-lactamase_39,P62593,1.02382,NO,58,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-2.914,-2.895,-0.019,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.0495842,0.00523369,1.02382 Pab1_G167C,Pab1_167,Pab1,Pab1,P04147,1.02383,NO,167,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.223,-2.243,1.02,,0.195,S,g,,0.03,,,,BOH,-1.25133,0.175299,0.00146449,1.02383 beta-lactamase_156_E61V,beta-lactamase_156_61,TEM-1,beta-lactamase_156,P62593,1.02384,NO,61,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.115,-3.784,1.669,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.111618,0.00440955,1.02384 beta-lactamase_N98L,beta-lactamase_98,TEM-1,beta-lactamase,P62593,1.02384,NO,98,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-2.973,-3.59,0.617,6.59973,0.963,G,A,1.07,1.35,1.332,,77.62,PPA,-2.07867,0.221079,0.00505389,1.02384 beta-lactamase_0_I93K,beta-lactamase_0_93,TEM-1,beta-lactamase_0,P62593,1.02385,NO,93,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.401,-3.873,2.472,,0.128,E,B,0.48,0.44,1.266,,67.83,BHB,-1.873,0.0500837,0.00527066,1.02385 beta-lactamase_39_E210Q,beta-lactamase_39_210,TEM-1,beta-lactamase_39,P62593,1.02385,NO,210,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.319,-2.627,0.308,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.0495842,0.00663582,1.02385 beta-lactamase_39_F70G,beta-lactamase_39_70,TEM-1,beta-lactamase_39,P62593,1.02385,NO,70,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.169,-3.574,2.405,,,H,A,0.58,-1.34,1.14,,63.99,PHB,-0.980667,0.0495842,0.00193499,1.02385 beta-lactamase_0_L135N,beta-lactamase_0_135,TEM-1,beta-lactamase_0,P62593,1.02386,NO,135,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.002,-4.152,3.15,,0.117,H,A,0.55,-0.58,0.705,,43.71,PHH,-1.03767,0.0500837,0.00244423,1.02386 beta-lactamase_39_S241A,beta-lactamase_39_241,TEM-1,beta-lactamase_39,P62593,1.02387,NO,241,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.0495842,0.00452736,1.02387 E1_Ubiquitin_F45T,E1_Ubiquitin_45,Uba1,E1_Ubiquitin,P0CG63,1.02387,NO,45,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.149,-3.464,2.315,,0.26,E,B,,-0.99,,,,HHH,-1.316,0.18783,0.00193245,1.02387 gb1_T251Y,gb1_251,gb1,gb1,P06654,1.02388,NO,251,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.794,-3.967,2.173,,,,,,,3.514,3.514,37.28,HPH,-1.56067,0.177985,0.00232932,1.02388 beta-lactamase_156_M209L,beta-lactamase_156_209,TEM-1,beta-lactamase_156,P62593,1.02389,NO,209,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.442,-1.689,0.247,,,H,A,0.55,-0.97,1.066,,64.69,HHA,-1.52633,0.111618,0.00625021,1.02389 beta-lactamase_39_D174K,beta-lactamase_39_174,TEM-1,beta-lactamase_39,P62593,1.02389,NO,174,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.738,-3.457,2.719,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.0495842,0.00125633,1.02389 beta-lactamase_39_S233G,beta-lactamase_39_233,TEM-1,beta-lactamase_39,P62593,1.02389,NO,233,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.886,-3.274,1.388,,0.016,E,B,0.27,-1.01,5.361,,77.62,BPO,-1.17267,0.0495842,0.00311415,1.02389 beta-lactamase_39_T158I,beta-lactamase_39_158,TEM-1,beta-lactamase_39,P62593,1.02389,NO,158,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.116,-3.731,2.615,,0.036,,B,0.22,-0.85,2.755,,69.58,HPB,-1.269,0.0495842,0.00341825,1.02389 PSD95pdz3_F340A,PSD95pdz3_340,PSD95pdz3,PSD95pdz3,P31016,1.02389,NO,340,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.524,-2.984,1.46,5.79283,,,,,11.8045,,,,PHH,-1.55767,0.0758425,0.000836987,1.02389 beta-lactamase_625_S201M,beta-lactamase_625_201,TEM-1,beta-lactamase_625,P62593,1.0239,NO,201,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.183,-4.493,3.31,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.213352,0.00198815,1.0239 beta-lactamase_156_Q88Y,beta-lactamase_156_88,TEM-1,beta-lactamase_156,P62593,1.02392,NO,88,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.086,-4.349,2.263,,0.807,,B,0.64,2.03,0.911,,77.62,APH,-1.53433,0.111618,0.00504167,1.02392 beta-lactamase_39_A235D,beta-lactamase_39_235,TEM-1,beta-lactamase_39,P62593,1.02392,NO,235,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.266,-3.668,2.402,,0.32,E,B,0.46,-0.86,1.344,,50,OHO,-0.89,0.0495842,0.00493474,1.02392 beta-lactamase_39_S201R,beta-lactamase_39_201,TEM-1,beta-lactamase_39,P62593,1.02392,NO,201,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.183,-3.779,2.596,,0.064,H,A,0.27,-0.07,3.54,,64.69,HPB,-1.451,0.0495842,0.00198815,1.02392 kka2_1:2_L81R,kka2_1:2_81,Kka2,kka2_1:2,P00552,1.02395,NO,81,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.427,-4.145,2.718,,0.46,E,A,1.59,-0.14,1.895,,63.64,HHA,-1.50567,0.295029,0.00805839,1.02395 beta-lactamase_0_G216L,beta-lactamase_0_216,TEM-1,beta-lactamase_0,P62593,1.02396,NO,216,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.477,-3.78,2.303,,0.437,I,A,0.29,-0.58,0.834,,74.48,HOO,-1.68067,0.0500837,0.00639568,1.02396 beta-lactamase_156_F228I,beta-lactamase_156_228,TEM-1,beta-lactamase_156,P62593,1.02396,NO,228,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-2.342,-3.049,0.707,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.111618,0.0046669,1.02396 WW_domain_P172T,WW_domain_172,Yap65,WW_domain,P46937,1.02397,NO,172,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.035,-3.198,2.163,,,,,,,,,,HOH,-1.233,0.153962,0.000991485,1.02397 beta-lactamase_V21C,beta-lactamase_21,TEM-1,beta-lactamase,P62593,1.02399,NO,21,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.873,-4.65,2.777,,,,,,,0.688,,93.01,OHH,-2.09633,0.221079,0.0028612,1.02399 beta-lactamase_625_E26S,beta-lactamase_625_26,TEM-1,beta-lactamase_625,P62593,1.024,NO,26,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.454,-3.34,0.886,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.213352,0.00297948,1.024 beta-lactamase_625_S256C,beta-lactamase_625_256,TEM-1,beta-lactamase_625,P62593,1.024,NO,256,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.213352,0.00710634,1.024 beta-lactamase_156_V29W,beta-lactamase_156_29,TEM-1,beta-lactamase_156,P62593,1.02401,NO,29,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-2.856,-5.465,2.609,,0.733,H,A,0.44,-0.78,3.685,,93.01,HHB,-2.24733,0.111618,0.00318969,1.02401 beta-lactamase_39_P60S,beta-lactamase_39_60,TEM-1,beta-lactamase_39,P62593,1.02401,NO,60,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-2.469,-2.362,-0.107,,0.256,T,A,0.52,-0.56,21.37,21.37,77.62,BOA,-1.97633,0.0495842,0.00521318,1.02401 beta-lactamase_156_R239F,beta-lactamase_156_239,TEM-1,beta-lactamase_156,P62593,1.02402,NO,239,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.111618,0.00213852,1.02402 gb1_K276A,gb1_276,gb1,gb1,P06654,1.02402,NO,276,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.456,-2.918,1.462,,,,,,,0.236,,12.72,PBP,-1.65133,0.177985,0.00620493,1.02402 gb1_T275N,gb1_275,gb1,gb1,P06654,1.02402,NO,275,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.727,-3.351,1.624,,,,,,,0.511,,35.71,HPB,-1.637,0.177985,0.00606618,1.02402 beta-lactamase_0_A182H,beta-lactamase_0_182,TEM-1,beta-lactamase_0,P62593,1.02403,NO,182,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.777,-3.358,1.581,,0.136,H,A,0.46,-0.66,10.765,10.765,93.01,OHH,-1.27367,0.0500837,0.00559099,1.02403 beta-lactamase_H285F,beta-lactamase_285,TEM-1,beta-lactamase,P62593,1.02403,NO,285,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-1.845,-3.847,2.002,5.64289,0.312,T,a,0.35,0.64,1.401,,72.73,BBH,-1.64567,0.221079,0.101555,1.02403 beta-lactamase_39_A215P,beta-lactamase_39_215,TEM-1,beta-lactamase_39,P62593,1.02404,NO,215,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.503,-3.85,2.347,,,,a,0.46,-0.93,0.494,,74.48,HHO,-1.42633,0.0495842,0.00544007,1.02404 beta-lactamase_39_T131E,beta-lactamase_39_131,TEM-1,beta-lactamase_39,P62593,1.02405,NO,131,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.328,-3.523,2.195,,,H,A,0.22,-0.69,3.306,,67.48,PPH,-1.00867,0.0495842,0.00345886,1.02405 beta-lactamase_2500_E26G,beta-lactamase_2500_26,TEM-1,beta-lactamase_2500,P62593,1.02406,NO,26,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.454,-2.639,0.185,,0.54,H,A,1.04,0.98,0.49,,93.01,OAP,-1.96167,0.361275,0.00297948,1.02406 kka2_1:2_Q155K,kka2_1:2_155,Kka2,kka2_1:2,P00552,1.02406,NO,155,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.606,-3.316,0.71,,0.525,T,A,0.64,1.49,1.592,,63.64,APA,-1.726,0.295029,0.00641853,1.02406 beta-lactamase_0_L38M,beta-lactamase_0_38,TEM-1,beta-lactamase_0,P62593,1.02407,NO,38,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.343,-4.186,2.843,,0.088,H,A,0.55,0.2,13.556,13.556,64.34,PHO,-1.78033,0.0500837,0.00373244,1.02407 beta-lactamase_156_A215H,beta-lactamase_156_215,TEM-1,beta-lactamase_156,P62593,1.02407,NO,215,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.503,-4.741,3.238,,,,a,0.46,-0.93,3.583,,74.48,HHO,-1.42633,0.111618,0.00544007,1.02407 beta-lactamase_156_R91E,beta-lactamase_156_91,TEM-1,beta-lactamase_156,P62593,1.02407,NO,91,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.392,-2.211,0.819,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.111618,0.00380226,1.02407 kka2_1:8_D159E,kka2_1:8_159,Kka2,kka2_1:8,P00552,1.02407,NO,159,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.82,-2.917,2.097,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.100394,0.0030485,1.02407 kka2_1:8_D159E,kka2_1:8_159,Kka2,kka2_1:8,P00552,1.02407,NO,159,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.82,-2.917,2.097,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.100394,0.0030485,1.02407 beta-lactamase_625_T112M,beta-lactamase_625_112,TEM-1,beta-lactamase_625,P62593,1.02408,NO,112,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.186,-4.812,2.626,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.213352,0.00531334,1.02408 kka2_1:4_L158H,kka2_1:4_158,Kka2,kka2_1:4,P00552,1.02408,NO,158,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.947,-4.683,2.736,,0.095,,B,1.59,0.77,7.588,,63.64,AHA,-1.25333,0.168804,0.00529068,1.02408 beta-lactamase_156_K30M,beta-lactamase_156_30,TEM-1,beta-lactamase_156,P62593,1.0241,NO,30,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-2.307,-4.578,2.271,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.111618,0.00448593,1.0241 beta-lactamase_E237S,beta-lactamase_237,TEM-1,beta-lactamase,P62593,1.02412,NO,237,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.058,-2.636,0.578,5.42877,0.583,S,B,1.62,1.2,2.144,,77.62,OAB,-1.61467,0.221079,0.0048626,1.02412 beta-lactamase_M180E,beta-lactamase_180,TEM-1,beta-lactamase,P62593,1.02412,NO,180,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-2.795,-3.532,0.737,4.96809,0.242,,B,1.07,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.221079,0.00552048,1.02412 beta-lactamase_39_I244T,beta-lactamase_39_244,TEM-1,beta-lactamase_39,P62593,1.02415,NO,244,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.555,-2.572,1.017,,,E,B,0.48,-0.84,1.325,,77.62,OHH,-1.385,0.0495842,0.00605379,1.02415 beta-lactamase_625_P255V,beta-lactamase_625_255,TEM-1,beta-lactamase_625,P62593,1.02415,NO,255,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.213352,0.00499612,1.02415 beta-lactamase_156_F58K,beta-lactamase_156_58,TEM-1,beta-lactamase_156,P62593,1.02416,NO,58,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-2.914,-3.623,0.709,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.111618,0.00523369,1.02416 gb1_D272G,gb1_272,gb1,gb1,P06654,1.02416,NO,272,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.457,-2.986,1.529,,,,,,,0.234,,11.83,HAA,-1.54533,0.177985,0.00218257,1.02416 beta-lactamase_625_E26P,beta-lactamase_625_26,TEM-1,beta-lactamase_625,P62593,1.02417,NO,26,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.454,-2.862,0.408,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.213352,0.00297948,1.02417 beta-lactamase_39_R118S,beta-lactamase_39_118,TEM-1,beta-lactamase_39,P62593,1.02418,NO,118,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.413,-2.394,-0.019,,0.457,H,A,1.2,1.39,3.961,,77.62,HBA,-1.785,0.0495842,0.00538794,1.02418 kka2_1:8_E17M,kka2_1:8_17,Kka2,kka2_1:8,P00552,1.02419,NO,17,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.154,-4.855,2.701,,0.957,T,A,1.04,0.22,31.483,31.483,63.64,HAB,-2.432,0.100394,0.00688738,1.02419 kka2_1:8_E17M,kka2_1:8_17,Kka2,kka2_1:8,P00552,1.02419,NO,17,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.154,-4.855,2.701,,0.957,T,A,1.04,0.22,31.483,31.483,63.64,HAB,-2.432,0.100394,0.00688738,1.02419 kka2_1:8_P98R,kka2_1:8_98,Kka2,kka2_1:8,P00552,1.02419,NO,98,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.526,-2.723,1.197,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.100394,0.00622754,1.02419 kka2_1:8_P98R,kka2_1:8_98,Kka2,kka2_1:8,P00552,1.02419,NO,98,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.526,-2.723,1.197,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.100394,0.00622754,1.02419 Ubiquitin_D52A,Ubiquitin_52,Uba1,Ubiquitin,P0CG48,1.02419,NO,52,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.43,-3.241,1.811,4.75143,0.421,T,A,,0.79,,,,AAO,-1.50267,0.205827,0.000806517,1.02419 Ubiquitin_D52G,Ubiquitin_52,Uba1,Ubiquitin,P0CG48,1.02419,NO,52,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.43,-2.481,1.051,4.75143,0.421,T,A,,0.79,,,,AAO,-1.50267,0.205827,0.000806517,1.02419 Ubiquitin_D52T,Ubiquitin_52,Uba1,Ubiquitin,P0CG48,1.02419,NO,52,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.43,-3.462,2.032,4.75143,0.421,T,A,,0.79,,,,AAO,-1.50267,0.205827,0.000806517,1.02419 Ubiquitin_E64M,Ubiquitin_64,Uba1,Ubiquitin,P0CG48,1.02419,NO,64,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.763,-4.783,3.02,5.084,0.54,T,l,,0.79,,,,BAP,-1.64433,0.205827,0.000817406,1.02419 Ubiquitin_E64N,Ubiquitin_64,Uba1,Ubiquitin,P0CG48,1.02419,NO,64,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.763,-2.708,0.945,5.084,0.54,T,l,,0.79,,,,BAP,-1.64433,0.205827,0.000817406,1.02419 Ubiquitin_G53C,Ubiquitin_53,Uba1,Ubiquitin,P0CG48,1.02419,NO,53,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.544,-2.933,1.389,5.32628,0.805,T,A,,-0.23,,,,AOB,-1.67033,0.205827,0.000662865,1.02419 Ubiquitin_G53H,Ubiquitin_53,Uba1,Ubiquitin,P0CG48,1.02419,NO,53,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.544,-2.886,1.342,5.32628,0.805,T,A,,-0.23,,,,AOB,-1.67033,0.205827,0.000662865,1.02419 Ubiquitin_G53M,Ubiquitin_53,Uba1,Ubiquitin,P0CG48,1.02419,NO,53,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.544,-4.784,3.24,5.32628,0.805,T,A,,-0.23,,,,AOB,-1.67033,0.205827,0.000662865,1.02419 Ubiquitin_G53P,Ubiquitin_53,Uba1,Ubiquitin,P0CG48,1.02419,NO,53,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.544,-3.996,2.452,5.32628,0.805,T,A,,-0.23,,,,AOB,-1.67033,0.205827,0.000662865,1.02419 Ubiquitin_G53S,Ubiquitin_53,Uba1,Ubiquitin,P0CG48,1.02419,NO,53,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.544,-2.361,0.817,5.32628,0.805,T,A,,-0.23,,,,AOB,-1.67033,0.205827,0.000662865,1.02419 Ubiquitin_G53T,Ubiquitin_53,Uba1,Ubiquitin,P0CG48,1.02419,NO,53,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.544,-3.561,2.017,5.32628,0.805,T,A,,-0.23,,,,AOB,-1.67033,0.205827,0.000662865,1.02419 Ubiquitin_G53V,Ubiquitin_53,Uba1,Ubiquitin,P0CG48,1.02419,NO,53,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.544,-2.894,1.35,5.32628,0.805,T,A,,-0.23,,,,AOB,-1.67033,0.205827,0.000662865,1.02419 Ubiquitin_P38E,Ubiquitin_38,Uba1,Ubiquitin,P0CG48,1.02419,NO,38,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.718,-2.87,1.152,5.0146,0.316,G,A,,-0.52,,,,OOA,-1.595,0.205827,0.000781418,1.02419 Ubiquitin_P38H,Ubiquitin_38,Uba1,Ubiquitin,P0CG48,1.02419,NO,38,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.718,-3.266,1.548,5.0146,0.316,G,A,,-0.52,,,,OOA,-1.595,0.205827,0.000781418,1.02419 Ubiquitin_Q31N,Ubiquitin_31,Uba1,Ubiquitin,P0CG48,1.02419,NO,31,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-1.678,-2.762,1.084,4.5004,0.464,H,A,,0.68,,,,HPA,-1.44467,0.205827,0.000724141,1.02419 Ubiquitin_Q62V,Ubiquitin_62,Uba1,Ubiquitin,P0CG48,1.02419,NO,62,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-1.836,-3.544,1.708,5.33616,0.762,,B,,0.79,,,,HPB,-1.66167,0.205827,0.00068944,1.02419 Ubiquitin_S65G,Ubiquitin_65,Uba1,Ubiquitin,P0CG48,1.02419,NO,65,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.535,-2.592,1.057,4.99442,0.168,,b,0.25,-0.68,16.756,16.756,33.87,APP,-1.626,0.205827,0.000546776,1.02419 Ubiquitin_S65N,Ubiquitin_65,Uba1,Ubiquitin,P0CG48,1.02419,NO,65,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.535,-3.603,2.068,4.99442,0.168,,b,0.25,-0.68,16.756,16.756,33.87,APP,-1.626,0.205827,0.000546776,1.02419 beta-lactamase_625_E46D,beta-lactamase_625_46,TEM-1,beta-lactamase_625,P62593,1.0242,NO,46,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.94,-3.652,1.712,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.213352,0.00427568,1.0242 beta-lactamase_625_A211R,beta-lactamase_625_211,TEM-1,beta-lactamase_625,P62593,1.02421,NO,211,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.896,-3.077,1.181,,0.369,T,A,0.46,-0.69,2.061,,77.62,AHA,-1.94633,0.213352,0.00648183,1.02421 beta-lactamase_625_T193K,beta-lactamase_625_193,TEM-1,beta-lactamase_625,P62593,1.02421,NO,193,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.914,-3.726,1.812,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.213352,0.00482669,1.02421 beta-lactamase_156_I171L,beta-lactamase_156_171,TEM-1,beta-lactamase_156,P62593,1.02422,NO,171,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-2.431,-1.98,-0.451,,0.361,,B,0.48,0.53,3.869,,77.62,HHO,-1.55533,0.111618,0.00623355,1.02422 kka2_1:8_L158Q,kka2_1:8_158,Kka2,kka2_1:8,P00552,1.02422,NO,158,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.947,-4.338,2.391,,0.095,.,B,0.55,0.77,1.607,,63.64,AHA,-1.25333,0.100394,0.00529068,1.02422 kka2_1:8_L158Q,kka2_1:8_158,Kka2,kka2_1:8,P00552,1.02422,NO,158,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.947,-4.338,2.391,,0.095,.,B,0.55,0.77,1.607,,63.64,AHA,-1.25333,0.100394,0.00529068,1.02422 beta-lactamase_0_L205H,beta-lactamase_0_205,TEM-1,beta-lactamase_0,P62593,1.02424,NO,205,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.922,-4.828,3.906,,,H,A,0.55,-0.46,1.065,,42.31,PHH,-1.57767,0.0500837,0.00255802,1.02424 beta-lactamase_2500_T138K,beta-lactamase_2500_138,TEM-1,beta-lactamase_2500,P62593,1.02424,NO,138,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.506,-2.186,-0.32,,0.662,H,A,0.22,-0.03,30.445,30.445,73.78,HPP,-1.81233,0.361275,0.00487868,1.02424 beta-lactamase_156_A211H,beta-lactamase_156_211,TEM-1,beta-lactamase_156,P62593,1.02426,NO,211,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.896,-3.336,1.44,,0.369,T,A,0.46,-0.69,8.527,8.527,77.62,AHA,-1.94633,0.111618,0.00648183,1.02426 beta-lactamase_A182F,beta-lactamase_182,TEM-1,beta-lactamase,P62593,1.02427,NO,182,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.777,-4.357,2.58,4.98609,0.136,H,A,0.52,-0.66,2.032,,93.01,OHH,-1.27367,0.221079,0.00559099,1.02427 beta-lactamase_F22H,beta-lactamase_22,TEM-1,beta-lactamase,P62593,1.02427,NO,22,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-2.676,-2.866,0.19,,,,,,,1.616,,73.08,HHH,-2.03233,0.221079,0.00262842,1.02427 beta-lactamase_H151K,beta-lactamase_151,TEM-1,beta-lactamase,P62593,1.02427,NO,151,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-2.96,-3.032,0.072,5.47408,0.594,H,A,0.35,0.1,1.843,,77.62,HBP,-2.34767,0.221079,0.00216946,1.02427 beta-lactamase_39_E195D,beta-lactamase_39_195,TEM-1,beta-lactamase_39,P62593,1.0243,NO,195,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.186,-1.979,-0.207,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.0495842,0.00496565,1.0243 beta-lactamase_625_T138R,beta-lactamase_625_138,TEM-1,beta-lactamase_625,P62593,1.02431,NO,138,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.506,-2.605,0.099,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.213352,0.00487868,1.02431 beta-lactamase_39_E108P,beta-lactamase_39_108,TEM-1,beta-lactamase_39,P62593,1.02432,NO,108,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.46,-3.855,2.395,,0.572,G,A,1.04,1.87,20.151,20.151,72.73,PAB,-1.437,0.0495842,0.00413372,1.02432 beta-lactamase_156_K109Q,beta-lactamase_156_109,TEM-1,beta-lactamase_156,P62593,1.02433,NO,109,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.734,-2.855,1.121,,0.787,G,A,2.34,2.21,6.031,,72.73,ABB,-1.63333,0.111618,0.00462493,1.02433 beta-lactamase_156_V106H,beta-lactamase_156_106,TEM-1,beta-lactamase_156,P62593,1.02434,NO,106,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.218,-4.937,3.719,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.111618,0.00304168,1.02434 kka2_1:8_D134G,kka2_1:8_134,Kka2,kka2_1:8,P00552,1.02434,NO,134,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.969,-3.259,2.29,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.100394,0.00270812,1.02434 kka2_1:8_D134G,kka2_1:8_134,Kka2,kka2_1:8,P00552,1.02434,NO,134,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.969,-3.259,2.29,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.100394,0.00270812,1.02434 beta-lactamase_39_D174I,beta-lactamase_39_174,TEM-1,beta-lactamase_39,P62593,1.02435,NO,174,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.738,-4.01,3.272,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.0495842,0.00125633,1.02435 beta-lactamase_0_R202C,beta-lactamase_0_202,TEM-1,beta-lactamase_0,P62593,1.02436,NO,202,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.292,-5.047,3.755,,0.188,H,A,1.2,0.62,7.016,,77.62,PBP,-1.54767,0.0500837,0.00321899,1.02436 beta-lactamase_39_P60R,beta-lactamase_39_60,TEM-1,beta-lactamase_39,P62593,1.02437,NO,60,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-2.469,-3.014,0.545,,0.256,T,A,0.52,-0.56,21.37,21.37,77.62,BOA,-1.97633,0.0495842,0.00521318,1.02437 beta-lactamase_625_I285Y,beta-lactamase_625_285,TEM-1,beta-lactamase_625,P62593,1.02437,NO,285,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.213352,0.101555,1.02437 WW_domain_M179K,WW_domain_179,Yap65,WW_domain,P46937,1.02437,NO,179,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.541,-3.234,1.693,6.54704,,,,,,,,,AHH,-1.31367,0.153962,0.00400164,1.02437 beta-lactamase_39_K32T,beta-lactamase_39_32,TEM-1,beta-lactamase_39,P62593,1.02439,NO,32,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.984,-2.479,0.495,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.0495842,0.00401283,1.02439 beta-lactamase_156_A84N,beta-lactamase_156_84,TEM-1,beta-lactamase_156,P62593,1.0244,NO,84,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.651,-2.768,1.117,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.111618,0.00503822,1.0244 beta-lactamase_2500_E210N,beta-lactamase_2500_210,TEM-1,beta-lactamase_2500,P62593,1.02442,NO,210,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.319,-3.904,1.585,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.361275,0.00663582,1.02442 beta-lactamase_T112L,beta-lactamase_112,TEM-1,beta-lactamase,P62593,1.02443,NO,112,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.186,-3.575,1.389,6.47162,0.921,T,A,0.77,1.06,2.04,,73.78,HPA,-1.925,0.221079,0.00531334,1.02443 beta-lactamase_39_A282V,beta-lactamase_39_282,TEM-1,beta-lactamase_39,P62593,1.02444,NO,282,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.0495842,0.0449821,1.02444 gb1_D248M,gb1_248,gb1,gb1,P06654,1.02444,NO,248,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.569,-4.491,2.922,,,,,,,0.344,,11.83,HAH,-1.673,0.177985,0.001865,1.02444 beta-lactamase_2500_F228Y,beta-lactamase_2500_228,TEM-1,beta-lactamase_2500,P62593,1.02445,NO,228,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-2.342,-4.005,1.663,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.361275,0.0046669,1.02445 beta-lactamase_39_K109N,beta-lactamase_39_109,TEM-1,beta-lactamase_39,P62593,1.02445,NO,109,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.734,-2.767,1.033,,0.787,G,A,2.34,2.21,7.243,,72.73,ABB,-1.63333,0.0495842,0.00462493,1.02445 beta-lactamase_156_A215Y,beta-lactamase_156_215,TEM-1,beta-lactamase_156,P62593,1.02446,NO,215,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.503,-4.339,2.836,,,,a,0.46,-0.93,3.583,,74.48,HHO,-1.42633,0.111618,0.00544007,1.02446 beta-lactamase_39_L223V,beta-lactamase_39_223,TEM-1,beta-lactamase_39,P62593,1.02446,NO,223,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.055,-2.195,1.14,,0.27,,B,0.55,0.09,1.511,,74.48,HHO,-1.35033,0.0495842,0.00372793,1.02446 beta-lactamase_E145G,beta-lactamase_145,TEM-1,beta-lactamase,P62593,1.02446,NO,145,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.357,-1.279,-1.078,5.38104,0.545,H,A,0.52,0.79,2.124,,77.62,BAH,-2.069,0.221079,0.00553285,1.02446 beta-lactamase_0_A246D,beta-lactamase_0_246,TEM-1,beta-lactamase_0,P62593,1.02447,NO,246,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.121,-4.086,1.965,,0.01,E,B,0.46,-1.01,1.201,,73.78,HHH,-1.55633,0.0500837,0.00569458,1.02447 beta-lactamase_156_E87S,beta-lactamase_156_87,TEM-1,beta-lactamase_156,P62593,1.02448,NO,87,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.421,-3.382,1.961,,0.048,,B,1.04,0.92,1.754,,64.69,PAP,-1.969,0.111618,0.00337888,1.02448 beta-lactamase_156_L55V,beta-lactamase_156_55,TEM-1,beta-lactamase_156,P62593,1.02448,NO,55,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.86,-2.346,0.486,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.111618,0.00403741,1.02448 beta-lactamase_39_E108R,beta-lactamase_39_108,TEM-1,beta-lactamase_39,P62593,1.02449,NO,108,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.46,-2.885,1.425,,0.572,G,A,1.04,1.87,20.151,20.151,72.73,PAB,-1.437,0.0495842,0.00413372,1.02449 beta-lactamase_39_A124Q,beta-lactamase_39_124,TEM-1,beta-lactamase_39,P62593,1.02451,NO,124,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.181,-4.004,2.823,,,H,A,0.46,-0.9,1.367,,64.34,HHH,-1.152,0.0495842,0.00481399,1.02451 beta-lactamase_39_A34Q,beta-lactamase_39_34,TEM-1,beta-lactamase_39,P62593,1.02451,NO,34,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.059,-4.16,2.101,,,H,A,0.46,-0.54,13.292,13.292,73.78,AHA,-1.74967,0.0495842,0.00407913,1.02451 WW_domain_S184F,WW_domain_184,Yap65,WW_domain,P46937,1.02451,NO,184,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.363,-3.907,2.544,5.06696,,,,,,,,,PPO,-1.39133,0.153962,0.00231095,1.02451 beta-lactamase_156_I93M,beta-lactamase_156_93,TEM-1,beta-lactamase_156,P62593,1.02453,NO,93,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.401,-4.189,2.788,,0.128,E,B,0.48,0.44,1.524,,67.83,BHB,-1.873,0.111618,0.00527066,1.02453 beta-lactamase_E145N,beta-lactamase_145,TEM-1,beta-lactamase,P62593,1.02454,NO,145,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.357,-3.655,1.298,5.38104,0.545,H,A,0.52,0.79,2.124,,77.62,BAH,-2.069,0.221079,0.00553285,1.02454 beta-lactamase_N152R,beta-lactamase_152,TEM-1,beta-lactamase,P62593,1.02454,NO,152,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-2.757,-2.835,0.078,5.98571,0.863,H,A,0.09,0.92,2.061,,77.62,BPH,-2.97,0.221079,0.00471429,1.02454 beta-lactamase_Q37V,beta-lactamase_37,TEM-1,beta-lactamase,P62593,1.02454,NO,37,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.134,-3.664,1.53,5.69153,0.613,H,A,0.12,1.98,1.318,,73.08,APH,-2.06967,0.221079,0.00425833,1.02454 kka2_1:2_Q100K,kka2_1:2_100,Kka2,kka2_1:2,P00552,1.02455,NO,100,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.77,-3.068,0.298,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.295029,0.0066405,1.02455 beta-lactamase_0_D36F,beta-lactamase_0_36,TEM-1,beta-lactamase_0,P62593,1.02456,NO,36,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.732,-4.318,1.586,,0.555,H,A,0.75,1.17,13.689,13.689,77.62,AAP,-1.91167,0.0500837,0.00476483,1.02456 beta-lactamase_156_V106Q,beta-lactamase_156_106,TEM-1,beta-lactamase_156,P62593,1.02456,NO,106,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.218,-4.248,3.03,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.111618,0.00304168,1.02456 kka2_1:8_L57T,kka2_1:8_57,Kka2,kka2_1:8,P00552,1.02456,NO,57,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.898,-3.729,1.831,,0.343,T,A,0.55,0.98,13.359,13.359,52.65,HHP,-2.20733,0.100394,0.00723769,1.02456 kka2_1:8_L57T,kka2_1:8_57,Kka2,kka2_1:8,P00552,1.02456,NO,57,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.898,-3.729,1.831,,0.343,T,A,0.55,0.98,13.359,13.359,52.65,HHP,-2.20733,0.100394,0.00723769,1.02456 beta-lactamase_156_V29Y,beta-lactamase_156_29,TEM-1,beta-lactamase_156,P62593,1.02457,NO,29,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-2.856,-4.329,1.473,,0.733,H,A,0.44,-0.78,3.685,,93.01,HHB,-2.24733,0.111618,0.00318969,1.02457 beta-lactamase_625_W208M,beta-lactamase_625_208,TEM-1,beta-lactamase_625,P62593,1.02457,NO,208,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-0.818,-4.48,3.662,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.213352,0.00126609,1.02457 beta-lactamase_0_A246Y,beta-lactamase_0_246,TEM-1,beta-lactamase_0,P62593,1.02458,NO,246,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.121,-4.018,1.897,,0.01,E,B,0.46,-1.01,1.201,,73.78,HHH,-1.55633,0.0500837,0.00569458,1.02458 beta-lactamase_625_E87C,beta-lactamase_625_87,TEM-1,beta-lactamase_625,P62593,1.02462,NO,87,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.421,-5.162,3.741,,0.048,,B,1.04,0.92,17.923,17.923,64.69,PAP,-1.969,0.213352,0.00337888,1.02462 beta-lactamase_I283Y,beta-lactamase_283,TEM-1,beta-lactamase,P62593,1.02462,NO,283,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.638,-3.948,2.31,5.4178,0.165,H,A,1.23,0.04,1.576,,69.23,HHB,-1.735,0.221079,0.0429138,1.02462 kka2_1:1_E149I,kka2_1:1_149,Kka2,kka2_1:1,P00552,1.02463,NO,149,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.994,-3.262,1.268,,0.674,H,A,1.04,1.63,3.671,,71.59,HAH,-1.59667,0.520039,0.00803343,1.02463 beta-lactamase_156_E87G,beta-lactamase_156_87,TEM-1,beta-lactamase_156,P62593,1.02464,NO,87,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.421,-3.541,2.12,,0.048,,B,1.04,0.92,1.754,,64.69,PAP,-1.969,0.111618,0.00337888,1.02464 beta-lactamase_156_I285L,beta-lactamase_156_285,TEM-1,beta-lactamase_156,P62593,1.02465,NO,285,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.111618,0.101555,1.02465 beta-lactamase_39_F228M,beta-lactamase_39_228,TEM-1,beta-lactamase_39,P62593,1.02466,NO,228,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-2.342,-3.369,1.027,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.0495842,0.0046669,1.02466 beta-lactamase_39_E166W,beta-lactamase_39_166,TEM-1,beta-lactamase_39,P62593,1.02468,NO,166,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.756,-5.495,3.739,,0.508,G,A,1.04,1.05,17.227,17.227,73.08,OAH,-1.42233,0.0495842,0.00512989,1.02468 beta-lactamase_625_V29E,beta-lactamase_625_29,TEM-1,beta-lactamase_625,P62593,1.02468,NO,29,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-2.856,-1.855,-1.001,,0.733,H,A,0.44,-0.78,1.931,,93.01,HHB,-2.24733,0.213352,0.00318969,1.02468 beta-lactamase_0_L38E,beta-lactamase_0_38,TEM-1,beta-lactamase_0,P62593,1.02469,NO,38,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.343,-3.797,2.454,,0.088,H,A,0.55,0.2,13.556,13.556,64.34,PHO,-1.78033,0.0500837,0.00373244,1.02469 beta-lactamase_39_S221C,beta-lactamase_39_221,TEM-1,beta-lactamase_39,P62593,1.0247,NO,221,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.754,-3.097,1.343,,0.624,H,A,0.27,-0.2,2.69,,74.48,BPH,-1.59967,0.0495842,0.0046094,1.0247 kka2_1:1_A9V,kka2_1:1_9,Kka2,kka2_1:1,P00552,1.0247,NO,9,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.079,-2.362,0.283,,,,,,,0.383,,71.59,BHO,-2.253,0.520039,0.00273264,1.0247 beta-lactamase_156_F228G,beta-lactamase_156_228,TEM-1,beta-lactamase_156,P62593,1.02472,NO,228,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-2.342,-3.572,1.23,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.111618,0.0046669,1.02472 kka2_1:8_L184K,kka2_1:8_184,Kka2,kka2_1:8,P00552,1.02472,NO,184,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.496,-2.828,1.332,,0.489,E,B,0.55,-0.06,4.495,,63.26,AHH,-1.24833,0.100394,0.00518742,1.02472 kka2_1:8_L184K,kka2_1:8_184,Kka2,kka2_1:8,P00552,1.02472,NO,184,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.496,-2.828,1.332,,0.489,E,B,0.55,-0.06,4.495,,63.26,AHH,-1.24833,0.100394,0.00518742,1.02472 beta-lactamase_625_I54V,beta-lactamase_625_54,TEM-1,beta-lactamase_625,P62593,1.02473,NO,54,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-2.838,-2.687,-0.151,,0.669,E,B,0.48,-0.14,3.946,,73.78,BHH,-2.337,0.213352,0.00403589,1.02473 beta-lactamase_39_T112N,beta-lactamase_39_112,TEM-1,beta-lactamase_39,P62593,1.02474,NO,112,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.186,-2.739,0.553,,0.921,T,A,0.22,1.06,2.87,,73.78,HPA,-1.925,0.0495842,0.00531334,1.02474 beta-lactamase_39_Q97D,beta-lactamase_39_97,TEM-1,beta-lactamase_39,P62593,1.02475,NO,97,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.072,-3.567,1.495,,0.823,G,A,0.64,2.42,4.457,,77.62,PPP,-2.43833,0.0495842,0.0045116,1.02475 kka2_1:1_V16Q,kka2_1:1_16,Kka2,kka2_1:1,P00552,1.02475,NO,16,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-3.087,-2.664,-0.423,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.520039,0.00694011,1.02475 beta-lactamase_156_T138E,beta-lactamase_156_138,TEM-1,beta-lactamase_156,P62593,1.02476,NO,138,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.506,-2.168,-0.338,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.111618,0.00487868,1.02476 beta-lactamase_625_Q88E,beta-lactamase_625_88,TEM-1,beta-lactamase_625,P62593,1.02476,NO,88,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.086,-2.76,0.674,,0.807,,B,0.64,2.03,1.84,,77.62,APH,-1.53433,0.213352,0.00504167,1.02476 Pab1_G177F,Pab1_177,Pab1,Pab1,P04147,1.02476,NO,177,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-2.24,-4.193,1.953,,,,,,,,,,AOH,-1.94067,0.175299,0.00170727,1.02476 Pab1_S147L,Pab1_147,Pab1,Pab1,P04147,1.02478,NO,147,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.267,-3.169,1.902,,0.336,H,A,,0.56,,,,HPH,-1.43033,0.175299,0.000610856,1.02478 beta-lactamase_39_F149D,beta-lactamase_39_149,TEM-1,beta-lactamase_39,P62593,1.0248,NO,149,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.299,-3.957,2.658,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.0495842,0.00418462,1.0248 beta-lactamase_39_N130G,beta-lactamase_39_130,TEM-1,beta-lactamase_39,P62593,1.0248,NO,130,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-0.798,-2.908,2.11,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.0495842,0.000683376,1.0248 WW_domain_S183G,WW_domain_183,Yap65,WW_domain,P46937,1.0248,NO,183,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.95,-3.086,1.136,5.35576,,,,,,1.594,,83.93,PPP,-1.48733,0.153962,0.00445513,1.0248 beta-lactamase_625_E26Y,beta-lactamase_625_26,TEM-1,beta-lactamase_625,P62593,1.02481,NO,26,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.454,-4.272,1.818,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.213352,0.00297948,1.02481 beta-lactamase_0_R239T,beta-lactamase_0_239,TEM-1,beta-lactamase_0,P62593,1.02482,NO,239,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.0500837,0.00213852,1.02482 beta-lactamase_156_A84Q,beta-lactamase_156_84,TEM-1,beta-lactamase_156,P62593,1.02483,NO,84,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.651,-2.658,1.007,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.111618,0.00503822,1.02483 kka2_1:4_V84L,kka2_1:4_84,Kka2,kka2_1:4,P00552,1.02483,NO,84,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-2.279,-2.527,0.248,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.168804,0.00724019,1.02483 beta-lactamase_0_F149D,beta-lactamase_0_149,TEM-1,beta-lactamase_0,P62593,1.02485,NO,149,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.299,-3.957,2.658,,0.195,H,A,0.58,0.11,3.518,,63.99,HHH,-1.46067,0.0500837,0.00418462,1.02485 beta-lactamase_39_S51N,beta-lactamase_39_51,TEM-1,beta-lactamase_39,P62593,1.02485,NO,51,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.526,-2.556,1.03,,0.496,T,A,0.27,0.26,2.964,,72.73,PPO,-1.88467,0.0495842,0.00504821,1.02485 beta-lactamase_Q86S,beta-lactamase_86,TEM-1,beta-lactamase,P62593,1.02485,NO,86,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.4,-2.711,0.311,5.39897,0.696,S,A,0.12,2.38,2.105,,77.62,OPA,-1.61067,0.221079,0.00450027,1.02485 gb1_T270S,gb1_270,gb1,gb1,P06654,1.02485,NO,270,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-3.15,-1.737,-1.413,,,,,,,1.326,,45.54,HPH,-1.843,0.177985,0.00223707,1.02485 gb1_T275G,gb1_275,gb1,gb1,P06654,1.02485,NO,275,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.727,-3.16,1.433,,,,,,,0.511,,35.71,HPB,-1.637,0.177985,0.00606618,1.02485 kka2_1:4_A150D,kka2_1:4_150,Kka2,kka2_1:4,P00552,1.02485,NO,150,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.949,-3.619,2.67,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.168804,0.0045009,1.02485 beta-lactamase_39_P255V,beta-lactamase_39_255,TEM-1,beta-lactamase_39,P62593,1.02486,NO,255,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.0495842,0.00499612,1.02486 beta-lactamase_D36A,beta-lactamase_36,TEM-1,beta-lactamase,P62593,1.02487,NO,36,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.732,-2.434,-0.298,5.39764,0.555,H,A,0.11,1.17,13.689,13.689,77.62,AAP,-1.91167,0.221079,0.00476483,1.02487 beta-lactamase_T112R,beta-lactamase_112,TEM-1,beta-lactamase,P62593,1.02487,NO,112,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.186,-3.88,1.694,6.47162,0.921,T,A,0.77,1.06,2.04,,73.78,HPA,-1.925,0.221079,0.00531334,1.02487 beta-lactamase_T193N,beta-lactamase_193,TEM-1,beta-lactamase,P62593,1.02487,NO,193,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.914,-2.715,0.801,5.67952,0.439,H,a,0.3,0.33,1.863,,63.99,HPO,-1.52133,0.221079,0.00482669,1.02487 beta-lactamase_156_V29S,beta-lactamase_156_29,TEM-1,beta-lactamase_156,P62593,1.0249,NO,29,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-2.856,-2.693,-0.163,,0.733,H,A,0.44,-0.78,3.685,,93.01,HHB,-2.24733,0.111618,0.00318969,1.0249 beta-lactamase_625_I285F,beta-lactamase_625_285,TEM-1,beta-lactamase_625,P62593,1.0249,NO,285,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.213352,0.101555,1.0249 beta-lactamase_156_H110F,beta-lactamase_156_110,TEM-1,beta-lactamase_156,P62593,1.02491,NO,110,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-1.706,-4.019,2.313,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.111618,0.00441499,1.02491 beta-lactamase_156_M180Q,beta-lactamase_156_180,TEM-1,beta-lactamase_156,P62593,1.02491,NO,180,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-2.795,-3.924,1.129,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.111618,0.00552048,1.02491 kka2_1:8_G74Y,kka2_1:8_74,Kka2,kka2_1:8,P00552,1.02492,NO,74,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.18,-4.468,3.288,,0.621,T,l,0.29,0.2,2.014,,64.39,POH,-1.91667,0.100394,0.00587035,1.02492 kka2_1:8_G74Y,kka2_1:8_74,Kka2,kka2_1:8,P00552,1.02492,NO,74,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.18,-4.468,3.288,,0.621,T,l,0.29,0.2,2.014,,64.39,POH,-1.91667,0.100394,0.00587035,1.02492 beta-lactamase_39_I244W,beta-lactamase_39_244,TEM-1,beta-lactamase_39,P62593,1.02493,NO,244,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.555,-5.375,3.82,,,E,B,0.48,-0.84,1.325,,77.62,OHH,-1.385,0.0495842,0.00605379,1.02493 beta-lactamase_39_E87V,beta-lactamase_39_87,TEM-1,beta-lactamase_39,P62593,1.02494,NO,87,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.421,-2.385,0.964,,0.048,,B,1.04,0.92,15.231,15.231,64.69,PAP,-1.969,0.0495842,0.00337888,1.02494 PSD95pdz3_S350M,PSD95pdz3_350,PSD95pdz3,PSD95pdz3,P31016,1.02494,NO,350,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.519,-4.162,2.643,4.97629,,,,,25.01,,,,HPO,-1.29133,0.0758425,0.000704883,1.02494 beta-lactamase_0_M153Y,beta-lactamase_0_153,TEM-1,beta-lactamase_0,P62593,1.02496,NO,153,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-3.193,-4.187,0.994,,0.14,T,A,0.55,-0.11,3.826,,77.62,PHO,-2.25767,0.0500837,0.00509109,1.02496 beta-lactamase_2500_A211L,beta-lactamase_2500_211,TEM-1,beta-lactamase_2500,P62593,1.02496,NO,211,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.896,-3.595,1.699,,0.369,T,A,0.46,-0.69,2.061,,77.62,AHA,-1.94633,0.361275,0.00648183,1.02496 beta-lactamase_39_C75V,beta-lactamase_39_75,TEM-1,beta-lactamase_39,P62593,1.02496,NO,75,C,V,CV,Special,Hydrophobic,5.07,5.60847,0.538465,192,121,117,-4,108.5,140,31.5,-1.245,-3.383,2.138,,,H,A,0.46,-0.87,2.369,,50,HOO,-1.24333,0.0495842,0.0034616,1.02496 beta-lactamase_625_I277M,beta-lactamase_625_277,TEM-1,beta-lactamase_625,P62593,1.02497,NO,277,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.213352,0.0169305,1.02497 beta-lactamase_39_E87M,beta-lactamase_39_87,TEM-1,beta-lactamase_39,P62593,1.02499,NO,87,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.421,-4.574,3.153,,0.048,,B,1.04,0.92,15.231,15.231,64.69,PAP,-1.969,0.0495842,0.00337888,1.02499 beta-lactamase_39_A230W,beta-lactamase_39_230,TEM-1,beta-lactamase_39,P62593,1.02501,NO,230,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.154,-5.319,4.165,,0.01,E,B,0.46,-1.17,1.171,,50,HHA,-1.079,0.0495842,0.00516841,1.02501 beta-lactamase_39_G249H,beta-lactamase_39_249,TEM-1,beta-lactamase_39,P62593,1.02501,NO,249,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.312,,,,0.256,S,B,0.23,0.04,30.841,30.841,72.73,HOO,-1.81367,0.0495842,0.00220169,1.02501 PSD95pdz3_R313N,PSD95pdz3_313,PSD95pdz3,PSD95pdz3,P31016,1.02501,NO,313,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.582,-3.13,1.548,6.63563,,,,,18.3955,,,,BBH,-1.59733,0.0758425,0.000840067,1.02501 beta-lactamase_A222R,beta-lactamase_222,TEM-1,beta-lactamase,P62593,1.02502,NO,222,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.103,-4.005,1.902,5.2262,0.233,H,A,0.47,-0.25,0.379,,77.62,PHH,-1.63733,0.221079,0.00466094,1.02502 PSD95pdz3_V362T,PSD95pdz3_362,PSD95pdz3,PSD95pdz3,P31016,1.02503,NO,362,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.465,-2.878,1.413,4.99436,,,,,19.6443,,,,PHP,-1.46467,0.0758425,0.000538527,1.02503 beta-lactamase_156_P105T,beta-lactamase_156_105,TEM-1,beta-lactamase_156,P62593,1.02504,NO,105,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.813,-3.385,2.572,,0.226,T,A,0.52,0.8,1.154,,63.29,POH,-1.01533,0.111618,0.0011981,1.02504 beta-lactamase_625_M180S,beta-lactamase_625_180,TEM-1,beta-lactamase_625,P62593,1.02504,NO,180,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-2.795,-2.032,-0.763,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.213352,0.00552048,1.02504 kka2_1:2_V186I,kka2_1:2_186,Kka2,kka2_1:2,P00552,1.02504,NO,186,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.011,-2.092,1.081,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.295029,0.00409703,1.02504 beta-lactamase_625_N152M,beta-lactamase_625_152,TEM-1,beta-lactamase_625,P62593,1.02505,NO,152,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-2.757,-4.737,1.98,,0.863,H,A,0.61,0.92,2.061,,77.62,BPH,-2.97,0.213352,0.00471429,1.02505 beta-lactamase_156_E26F,beta-lactamase_156_26,TEM-1,beta-lactamase_156,P62593,1.0251,NO,26,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.454,-4.297,1.843,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.111618,0.00297948,1.0251 kka2_1:8_A13S,kka2_1:8_13,Kka2,kka2_1:8,P00552,1.0251,NO,13,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.248,-2.545,0.297,,0.689,G,A,1.04,0.99,14.966,14.966,92.05,OHH,-1.646,0.100394,0.00784241,1.0251 kka2_1:8_A13S,kka2_1:8_13,Kka2,kka2_1:8,P00552,1.0251,NO,13,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.248,-2.545,0.297,,0.689,G,A,1.04,0.99,14.966,14.966,92.05,OHH,-1.646,0.100394,0.00784241,1.0251 PSD95pdz3_A390S,PSD95pdz3_390,PSD95pdz3,PSD95pdz3,P31016,1.02511,NO,390,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.307,-2.617,1.31,5.03823,,,,,12.46,,,,HHP,-1.54467,0.0758425,0.00104603,1.02511 beta-lactamase_625_M209L,beta-lactamase_625_209,TEM-1,beta-lactamase_625,P62593,1.02512,NO,209,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.442,-1.689,0.247,,,H,A,0.55,-0.97,1.167,,64.69,HHA,-1.52633,0.213352,0.00625021,1.02512 beta-lactamase_2500_T112I,beta-lactamase_2500_112,TEM-1,beta-lactamase_2500,P62593,1.02513,NO,112,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.186,-3.949,1.763,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.361275,0.00531334,1.02513 beta-lactamase_625_R202Q,beta-lactamase_625_202,TEM-1,beta-lactamase_625,P62593,1.02514,NO,202,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.292,-1.95,0.658,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.213352,0.00321899,1.02514 beta-lactamase_Q37N,beta-lactamase_37,TEM-1,beta-lactamase,P62593,1.02514,NO,37,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.134,-3.706,1.572,5.69153,0.613,H,A,0.12,1.98,1.318,,73.08,APH,-2.06967,0.221079,0.00425833,1.02514 beta-lactamase_T138E,beta-lactamase_138,TEM-1,beta-lactamase,P62593,1.02514,NO,138,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.506,-2.168,-0.338,5.52585,0.662,H,A,0.3,-0.03,30.445,30.445,73.78,HPP,-1.81233,0.221079,0.00487868,1.02514 Pab1_Q194R,Pab1_194,Pab1,Pab1,P04147,1.02518,NO,194,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.179,-2.12,-0.059,,,,,,,,,,OPA,-1.59767,0.175299,0.0016145,1.02518 beta-lactamase_625_E87M,beta-lactamase_625_87,TEM-1,beta-lactamase_625,P62593,1.02519,NO,87,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.421,-4.574,3.153,,0.048,,B,1.04,0.92,17.923,17.923,64.69,PAP,-1.969,0.213352,0.00337888,1.02519 beta-lactamase_625_R118W,beta-lactamase_625_118,TEM-1,beta-lactamase_625,P62593,1.02521,NO,118,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.413,-5.439,3.026,,0.457,H,A,1.2,1.39,2.144,,77.62,HBA,-1.785,0.213352,0.00538794,1.02521 beta-lactamase_625_E210I,beta-lactamase_625_210,TEM-1,beta-lactamase_625,P62593,1.02522,NO,210,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.319,-2.456,0.137,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.213352,0.00663582,1.02522 beta-lactamase_625_T131V,beta-lactamase_625_131,TEM-1,beta-lactamase_625,P62593,1.02523,NO,131,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.328,-3.345,2.017,,,H,A,0.22,-0.69,2.031,,67.48,PPH,-1.00867,0.213352,0.00345886,1.02523 beta-lactamase_156_P65K,beta-lactamase_156_65,TEM-1,beta-lactamase_156,P62593,1.02526,NO,65,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.894,-3.511,2.617,,0.098,E,B,0.52,-0.62,0.623,,40.56,HOH,-1.03233,0.111618,0.00152776,1.02526 kka2_1:4_N58S,kka2_1:4_58,Kka2,kka2_1:4,P00552,1.02526,NO,58,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-2.641,-1.901,-0.74,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.168804,0.00793425,1.02526 kka2_1:8_A87E,kka2_1:8_87,Kka2,kka2_1:8,P00552,1.02526,NO,87,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.917,-2.476,0.559,,1.039,S,L,0.46,1.57,16.115,16.115,65.53,AHO,-1.822,0.100394,0.00791281,1.02526 kka2_1:8_A87E,kka2_1:8_87,Kka2,kka2_1:8,P00552,1.02526,NO,87,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.917,-2.476,0.559,,1.039,S,L,0.46,1.57,16.115,16.115,65.53,AHO,-1.822,0.100394,0.00791281,1.02526 kka2_1:8_G95L,kka2_1:8_95,Kka2,kka2_1:8,P00552,1.02526,NO,95,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-2.403,-3.574,1.171,,0.126,E,B,0.75,-0.74,7.774,,71.59,HOA,-2.198,0.100394,0.00743616,1.02526 kka2_1:8_G95L,kka2_1:8_95,Kka2,kka2_1:8,P00552,1.02526,NO,95,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-2.403,-3.574,1.171,,0.126,E,B,0.75,-0.74,7.774,,71.59,HOA,-2.198,0.100394,0.00743616,1.02526 PSD95pdz3_A378E,PSD95pdz3_378,PSD95pdz3,PSD95pdz3,P31016,1.02528,NO,378,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.307,-3.122,1.815,4.86582,,,,,14.576,,,,HHH,-1.509,0.0758425,0.000313169,1.02528 beta-lactamase_156_L219E,beta-lactamase_156_219,TEM-1,beta-lactamase_156,P62593,1.0253,NO,219,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.313,-3.999,2.686,,,I,A,0.55,-0.51,2.321,,74.48,HHB,-1.21533,0.111618,0.00664345,1.0253 beta-lactamase_39_T186A,beta-lactamase_39_186,TEM-1,beta-lactamase_39,P62593,1.02531,NO,186,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.522,-1.898,-0.624,,0.396,H,A,0.22,-0.28,0.515,,77.62,HPP,-1.77633,0.0495842,0.00485034,1.02531 beta-lactamase_Q97V,beta-lactamase_97,TEM-1,beta-lactamase,P62593,1.02531,NO,97,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.072,-3.633,1.561,6.30204,0.823,G,A,1.1,2.42,1.157,,77.62,PPP,-2.43833,0.221079,0.0045116,1.02531 kka2_1:2_A79M,kka2_1:2_79,Kka2,kka2_1:2,P00552,1.02531,NO,79,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.368,-3.668,1.3,,0.563,.,B,0.46,-0.43,0.475,,71.59,HHH,-1.752,0.295029,0.00664821,1.02531 beta-lactamase_2500_G253K,beta-lactamase_2500_253,TEM-1,beta-lactamase_2500,P62593,1.02532,NO,253,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.361275,0.00786358,1.02532 beta-lactamase_39_S122H,beta-lactamase_39_122,TEM-1,beta-lactamase_39,P62593,1.02532,NO,122,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.406,-2.676,0.27,,0.352,H,A,0.27,-0.54,2.004,,77.62,OPH,-1.39767,0.0495842,0.00497825,1.02532 kka2_1:1_L57R,kka2_1:1_57,Kka2,kka2_1:1,P00552,1.02532,NO,57,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.898,-4.138,2.24,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.520039,0.00723769,1.02532 beta-lactamase_39_P255F,beta-lactamase_39_255,TEM-1,beta-lactamase_39,P62593,1.02534,NO,255,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.0495842,0.00499612,1.02534 kka2_1:4_A110G,kka2_1:4_110,Kka2,kka2_1:4,P00552,1.02534,NO,110,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.064,-2.863,0.799,,0.175,H,A,0.46,-1.19,23.237,23.237,71.59,OHA,-1.91867,0.168804,0.00759851,1.02534 beta-lactamase_2500_A211Q,beta-lactamase_2500_211,TEM-1,beta-lactamase_2500,P62593,1.02535,NO,211,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.896,-3.096,1.2,,0.369,T,A,0.46,-0.69,2.061,,77.62,AHA,-1.94633,0.361275,0.00648183,1.02535 kka2_1:8_Q163T,kka2_1:8_163,Kka2,kka2_1:8,P00552,1.02536,NO,163,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.162,-2.589,0.427,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.100394,0.00719507,1.02536 kka2_1:8_Q163T,kka2_1:8_163,Kka2,kka2_1:8,P00552,1.02536,NO,163,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.162,-2.589,0.427,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.100394,0.00719507,1.02536 kka2_1:8_T28S,kka2_1:8_28,Kka2,kka2_1:8,P00552,1.02536,NO,28,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.883,-2.337,0.454,,0.353,S,B,0.22,2.02,18.114,18.114,63.64,PPH,-1.74467,0.100394,0.00743084,1.02536 kka2_1:8_T28S,kka2_1:8_28,Kka2,kka2_1:8,P00552,1.02536,NO,28,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.883,-2.337,0.454,,0.353,S,B,0.22,2.02,18.114,18.114,63.64,PPH,-1.74467,0.100394,0.00743084,1.02536 beta-lactamase_39_T186K,beta-lactamase_39_186,TEM-1,beta-lactamase_39,P62593,1.02538,NO,186,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.522,-2.678,0.156,,0.396,H,A,0.22,-0.28,0.515,,77.62,HPP,-1.77633,0.0495842,0.00485034,1.02538 beta-lactamase_39_T187Q,beta-lactamase_39_187,TEM-1,beta-lactamase_39,P62593,1.02538,NO,187,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.401,-4.004,2.603,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.0495842,0.00491782,1.02538 beta-lactamase_0_H24N,beta-lactamase_0_24,TEM-1,beta-lactamase_0,P62593,1.0254,NO,24,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-2.481,-3.496,1.015,,,,,,,2.708,,93.01,OBO,-2.0035,0.0500837,0.00238894,1.0254 PSD95pdz3_G319P,PSD95pdz3_319,PSD95pdz3,PSD95pdz3,P31016,1.0254,NO,319,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.008,-3.561,2.553,4.95387,,,,,18.8725,,,,BOP,-1.36967,0.0758425,0.00109317,1.0254 beta-lactamase_625_L28H,beta-lactamase_625_28,TEM-1,beta-lactamase_625,P62593,1.02541,NO,28,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.579,-4.838,3.259,,0.277,H,A,0.55,-0.16,2.716,,93.01,PHH,-2.11333,0.213352,0.00359321,1.02541 beta-lactamase_39_L89M,beta-lactamase_39_89,TEM-1,beta-lactamase_39,P62593,1.02542,NO,89,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.096,-2.928,1.832,,0.168,T,A,0.55,0.63,3.233,,64.34,PHO,-1.75767,0.0495842,0.00207068,1.02542 beta-lactamase_625_V29D,beta-lactamase_625_29,TEM-1,beta-lactamase_625,P62593,1.02543,NO,29,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-2.856,-2.298,-0.558,,0.733,H,A,0.44,-0.78,1.931,,93.01,HHB,-2.24733,0.213352,0.00318969,1.02543 kka2_1:2_E199M,kka2_1:2_199,Kka2,kka2_1:2,P00552,1.02544,NO,199,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.234,-4.802,2.568,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.295029,0.00854122,1.02544 Pab1_A178I,Pab1_178,Pab1,Pab1,P04147,1.02544,NO,178,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.579,-2.507,0.928,,0.019,H,A,0.64,0.64,2.7,,81.63,OHH,-1.61067,0.175299,0.00160192,1.02544 beta-lactamase_0_S266G,beta-lactamase_0_266,TEM-1,beta-lactamase_0,P62593,1.02545,NO,266,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.0500837,0.0140785,1.02545 beta-lactamase_0_L38W,beta-lactamase_0_38,TEM-1,beta-lactamase_0,P62593,1.02546,NO,38,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.343,-5.229,3.886,,0.088,H,A,0.55,0.2,13.556,13.556,64.34,PHO,-1.78033,0.0500837,0.00373244,1.02546 PSD95pdz3_Y392E,PSD95pdz3_392,PSD95pdz3,PSD95pdz3,P31016,1.02546,NO,392,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-1.437,-3.347,1.91,5.20337,,,,,11.725,,,,PHB,-1.51733,0.0758425,0.000935211,1.02546 beta-lactamase_156_R92I,beta-lactamase_156_92,TEM-1,beta-lactamase_156,P62593,1.02547,NO,92,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.718,-3.773,2.055,,0.479,E,B,1.2,1.36,19.112,19.112,65.38,BBH,-1.50367,0.111618,0.00429626,1.02547 PSD95pdz3_Q391C,PSD95pdz3_391,PSD95pdz3,PSD95pdz3,P31016,1.02548,NO,391,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-1.699,-4.769,3.07,5.50275,,,,,12.6589,,,,HPH,-1.481,0.0758425,0.000990786,1.02548 beta-lactamase_0_I245W,beta-lactamase_0_245,TEM-1,beta-lactamase_0,P62593,1.02551,NO,245,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.0500837,0.00391032,1.02551 beta-lactamase_0_D177L,beta-lactamase_0_177,TEM-1,beta-lactamase_0,P62593,1.02552,NO,177,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.967,-3.772,2.805,,0.006,T,L,0.75,-1.02,3.536,,64.69,BAP,-0.873667,0.0500837,0.000864022,1.02552 beta-lactamase_156_T112W,beta-lactamase_156_112,TEM-1,beta-lactamase_156,P62593,1.02552,NO,112,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.186,-5.474,3.288,,0.921,T,A,0.22,1.06,2.87,,73.78,HPA,-1.925,0.111618,0.00531334,1.02552 beta-lactamase_39_L47W,beta-lactamase_39_47,TEM-1,beta-lactamase_39,P62593,1.02552,NO,47,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.876,-5.24,3.364,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.0495842,0.00439844,1.02552 kka2_1:2_I246V,kka2_1:2_246,Kka2,kka2_1:2,P00552,1.02552,NO,246,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-2.008,-2.046,0.038,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.295029,0.0139479,1.02552 beta-lactamase_0_N173E,beta-lactamase_0_173,TEM-1,beta-lactamase_0,P62593,1.02553,NO,173,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-2.663,-3.453,0.79,,1.044,T,l,0.61,1.25,1.133,,77.62,OPA,-1.46633,0.0500837,0.0033769,1.02553 beta-lactamase_156_T131M,beta-lactamase_156_131,TEM-1,beta-lactamase_156,P62593,1.02554,NO,131,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.328,-4.602,3.274,,,H,A,0.22,-0.69,2.031,,67.48,PPH,-1.00867,0.111618,0.00345886,1.02554 gb1_T270M,gb1_270,gb1,gb1,P06654,1.02554,NO,270,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-3.15,-4.379,1.229,,,,,,,1.326,,45.54,HPH,-1.843,0.177985,0.00223707,1.02554 gb1_T275E,gb1_275,gb1,gb1,P06654,1.02554,NO,275,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.727,-3.204,1.477,,,,,,,0.511,,35.71,HPB,-1.637,0.177985,0.00606618,1.02554 gb1_T279S,gb1_279,gb1,gb1,P06654,1.02554,NO,279,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.32,-2.927,1.607,,,,,,,0.529,,35.71,HPH,-1.50067,0.177985,0.00421454,1.02554 beta-lactamase_39_H24C,beta-lactamase_39_24,TEM-1,beta-lactamase_39,P62593,1.02555,NO,24,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-2.481,-4.897,2.416,,,,,,,2.708,,93.01,OBO,-2.0035,0.0495842,0.00238894,1.02555 beta-lactamase_39_R59S,beta-lactamase_39_59,TEM-1,beta-lactamase_39,P62593,1.02555,NO,59,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.345,-2.706,1.361,,0.329,S,L,1.2,-0.09,1.806,,73.08,HBO,-2.24267,0.0495842,0.00318082,1.02555 beta-lactamase_625_E46H,beta-lactamase_625_46,TEM-1,beta-lactamase_625,P62593,1.02555,NO,46,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.94,-4.828,2.888,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.213352,0.00427568,1.02555 beta-lactamase_39_P143W,beta-lactamase_39_143,TEM-1,beta-lactamase_39,P62593,1.02556,NO,143,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.967,-5.497,4.53,,0.075,H,A,0.52,-0.37,0.976,,66.78,OOB,-1.354,0.0495842,0.00114551,1.02556 beta-lactamase_0_Q88L,beta-lactamase_0_88,TEM-1,beta-lactamase_0,P62593,1.02557,NO,88,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.086,-3.504,1.418,,0.807,,B,0.64,2.03,0.4,,77.62,APH,-1.53433,0.0500837,0.00504167,1.02557 beta-lactamase_A246M,beta-lactamase_246,TEM-1,beta-lactamase,P62593,1.02557,NO,246,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.121,-2.882,0.761,4.78979,0.01,E,B,0.52,-1.01,1.26,,73.78,HHH,-1.55633,0.221079,0.00569458,1.02557 beta-lactamase_K30T,beta-lactamase_30,TEM-1,beta-lactamase,P62593,1.02557,NO,30,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-2.307,-2.199,-0.108,5.30605,0.142,H,A,1.82,-0.65,2.434,,93.01,HBH,-2.32833,0.221079,0.00448593,1.02557 beta-lactamase_Q37K,beta-lactamase_37,TEM-1,beta-lactamase,P62593,1.02557,NO,37,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.134,-2.595,0.461,5.69153,0.613,H,A,0.12,1.98,1.318,,73.08,APH,-2.06967,0.221079,0.00425833,1.02557 beta-lactamase_625_K254D,beta-lactamase_625_254,TEM-1,beta-lactamase_625,P62593,1.02559,NO,254,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.213352,0.00369,1.02559 beta-lactamase_P224P,beta-lactamase_224,TEM-1,beta-lactamase,P62593,1.02561,NO,224,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.893,-0.893,,5.179,0.383,,B,0.99,-0.3,0.383,,74.48,HOH,-1.26433,0.221079,0.00189564,1.02561 beta-lactamase_D269E,beta-lactamase_269,TEM-1,beta-lactamase,P62593,1.02562,NO,269,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.156,-2.148,-0.008,5.47645,0.646,H,A,0.23,0.4,21.796,21.796,77.62,HAA,-1.96733,0.221079,0.00950944,1.02562 beta-lactamase_N98T,beta-lactamase_98,TEM-1,beta-lactamase,P62593,1.02562,NO,98,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-2.973,-2.907,-0.066,6.59973,0.963,G,A,1.07,1.35,1.332,,77.62,PPA,-2.07867,0.221079,0.00505389,1.02562 beta-lactamase_156_L100E,beta-lactamase_156_100,TEM-1,beta-lactamase_156,P62593,1.02563,NO,100,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.218,-3.935,2.717,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.111618,0.00413885,1.02563 beta-lactamase_156_P25Q,beta-lactamase_156_25,TEM-1,beta-lactamase_156,P62593,1.02564,NO,25,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.526,-2.522,0.996,,0.624,H,A,0.52,0.14,1.079,,73.08,BOA,-2.15367,0.111618,0.00347571,1.02564 E1_Ubiquitin_R72R,E1_Ubiquitin_72,Uba1,E1_Ubiquitin,P0CG63,1.02564,NO,72,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.184,-1.184,,,0.077,,B,0.16,-0.1,,,,HBH,-1.08733,0.18783,0.00129853,1.02564 PSD95pdz3_Q391D,PSD95pdz3_391,PSD95pdz3,PSD95pdz3,P31016,1.02564,NO,391,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-1.699,-2.925,1.226,5.50275,,,,,12.6589,,,,HPH,-1.481,0.0758425,0.000990786,1.02564 beta-lactamase_0_E87G,beta-lactamase_0_87,TEM-1,beta-lactamase_0,P62593,1.02567,NO,87,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.421,-3.541,2.12,,0.048,,B,1.04,0.92,1.159,,64.69,PAP,-1.969,0.0500837,0.00337888,1.02567 beta-lactamase_156_E279Y,beta-lactamase_156_279,TEM-1,beta-lactamase_156,P62593,1.02567,NO,279,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.111618,0.0192826,1.02567 kka2_1:2_T85N,kka2_1:2_85,Kka2,kka2_1:2,P00552,1.02567,NO,85,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.165,-3.801,1.636,,0.576,E,B,0.22,1.39,1.853,,71.59,HPA,-2.10133,0.295029,0.00634493,1.02567 beta-lactamase_156_D271E,beta-lactamase_156_271,TEM-1,beta-lactamase_156,P62593,1.02568,NO,271,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.111618,0.00752082,1.02568 beta-lactamase_625_R159F,beta-lactamase_625_159,TEM-1,beta-lactamase_625,P62593,1.02568,NO,159,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-0.94,-4.255,3.315,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.213352,0.00108472,1.02568 beta-lactamase_A222C,beta-lactamase_222,TEM-1,beta-lactamase,P62593,1.02568,NO,222,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.103,-4.939,2.836,5.2262,0.233,H,A,0.47,-0.25,0.379,,77.62,PHH,-1.63733,0.221079,0.00466094,1.02568 beta-lactamase_39_R176D,beta-lactamase_39_176,TEM-1,beta-lactamase_39,P62593,1.0257,NO,176,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-0.863,-3.694,2.831,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.0495842,0.00105554,1.0257 beta-lactamase_39_K109M,beta-lactamase_39_109,TEM-1,beta-lactamase_39,P62593,1.02572,NO,109,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.734,-4.742,3.008,,0.787,G,A,2.34,2.21,7.243,,72.73,ABB,-1.63333,0.0495842,0.00462493,1.02572 PSD95pdz3_R354V,PSD95pdz3_354,PSD95pdz3,PSD95pdz3,P31016,1.02574,NO,354,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.582,-3.435,1.853,6.21887,,,,,23.7791,,,,HBB,-1.44833,0.0758425,0.000650924,1.02574 beta-lactamase_0_D33Q,beta-lactamase_0_33,TEM-1,beta-lactamase_0,P62593,1.02575,NO,33,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.321,-2.638,0.317,,0.366,H,A,0.75,0.33,12.514,12.514,77.62,BAH,-2.12133,0.0500837,0.00435556,1.02575 beta-lactamase_0_S80G,beta-lactamase_0_80,TEM-1,beta-lactamase_0,P62593,1.02576,NO,80,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.029,-3.327,1.298,,0.192,H,A,0.27,0.46,12.403,12.403,77.62,HPB,-1.44567,0.0500837,0.00565569,1.02576 beta-lactamase_39_S80Y,beta-lactamase_39_80,TEM-1,beta-lactamase_39,P62593,1.02576,NO,80,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.029,-4.297,2.268,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.0495842,0.00565569,1.02576 beta-lactamase_156_V260M,beta-lactamase_156_260,TEM-1,beta-lactamase_156,P62593,1.02577,NO,260,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.111618,0.00471757,1.02577 beta-lactamase_39_V214S,beta-lactamase_39_214,TEM-1,beta-lactamase_39,P62593,1.02577,NO,214,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.299,-3.408,2.109,,0.375,S,A,0.44,-0.44,18.838,18.838,74.48,BHH,-1.53733,0.0495842,0.00628442,1.02577 beta-lactamase_2500_A268N,beta-lactamase_2500_268,TEM-1,beta-lactamase_2500,P62593,1.02578,NO,268,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.361275,0.0102525,1.02578 beta-lactamase_2500_E26K,beta-lactamase_2500_26,TEM-1,beta-lactamase_2500,P62593,1.02578,NO,26,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.454,-3.374,0.92,,0.54,H,A,1.04,0.98,0.49,,93.01,OAP,-1.96167,0.361275,0.00297948,1.02578 PSD95pdz3_K355M,PSD95pdz3_355,PSD95pdz3,PSD95pdz3,P31016,1.02579,NO,355,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.416,-4.162,2.746,5.56865,,,,,17.2556,,,,BBO,-1.33533,0.0758425,0.00063703,1.02579 beta-lactamase_625_P224N,beta-lactamase_625_224,TEM-1,beta-lactamase_625,P62593,1.0258,NO,224,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.893,-3.802,2.909,,0.383,,B,0.52,-0.3,1.35,,74.48,HOH,-1.26433,0.213352,0.00189564,1.0258 beta-lactamase_39_M127N,beta-lactamase_39_127,TEM-1,beta-lactamase_39,P62593,1.02581,NO,127,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-2.251,-4.047,1.796,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.0495842,0.00437927,1.02581 beta-lactamase_39_P224E,beta-lactamase_39_224,TEM-1,beta-lactamase_39,P62593,1.02581,NO,224,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.893,-3.439,2.546,,0.383,,B,0.52,-0.3,3.169,,74.48,HOH,-1.26433,0.0495842,0.00189564,1.02581 gb1_E245M,gb1_245,gb1,gb1,P06654,1.02581,NO,245,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.725,-4.215,1.49,,,,,,,0.712,,45.54,PAH,-1.84567,0.177985,0.00158611,1.02581 gb1_K239C,gb1_239,gb1,gb1,P06654,1.02581,NO,239,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-3.043,-4.648,1.605,,,,,,,1.326,,45.54,HBO,-2.31467,0.177985,0.00207004,1.02581 gb1_T277C,gb1_277,gb1,gb1,P06654,1.02581,NO,277,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.771,-4.601,2.83,,,,,,,0.824,,35.71,BPH,-1.54833,0.177985,0.00348258,1.02581 beta-lactamase_156_D231M,beta-lactamase_156_231,TEM-1,beta-lactamase_156,P62593,1.02582,NO,231,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.816,-4.927,4.111,,,E,B,0.75,-1.06,2.66,,65.38,HAB,-0.994,0.111618,0.00107395,1.02582 kka2_1:4_R18V,kka2_1:4_18,Kka2,kka2_1:4,P00552,1.02582,NO,18,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.055,-3.089,1.034,,0.474,T,A,1.2,0.54,8.405,8.405,71.59,ABH,-1.821,0.168804,0.00724065,1.02582 beta-lactamase_39_G216S,beta-lactamase_39_216,TEM-1,beta-lactamase_39,P62593,1.02583,NO,216,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.477,-3.283,1.806,,0.437,I,A,0.29,-0.58,0.834,,74.48,HOO,-1.68067,0.0495842,0.00639568,1.02583 beta-lactamase_625_A148N,beta-lactamase_625_148,TEM-1,beta-lactamase_625,P62593,1.02584,NO,148,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.757,-3.701,1.944,,0.379,H,A,0.46,-0.55,1.359,,72.73,PHH,-1.40167,0.213352,0.00547053,1.02584 beta-lactamase_156_P65V,beta-lactamase_156_65,TEM-1,beta-lactamase_156,P62593,1.02585,NO,65,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.894,-3.39,2.496,,0.098,E,B,0.52,-0.62,0.623,,40.56,HOH,-1.03233,0.111618,0.00152776,1.02585 beta-lactamase_39_R220T,beta-lactamase_39_220,TEM-1,beta-lactamase_39,P62593,1.02585,NO,220,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-0.942,-3.419,2.477,,0.295,I,A,1.2,-0.76,1.596,,74.48,HBP,-1.33633,0.0495842,0.00232421,1.02585 kka2_1:2_M116R,kka2_1:2_116,Kka2,kka2_1:2,P00552,1.02585,NO,116,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-2.482,-4.144,1.662,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.295029,0.00745147,1.02585 Pab1_N192V,Pab1_192,Pab1,Pab1,P04147,1.02585,NO,192,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-1.079,-3.571,2.492,,0.619,T,l,,2.28,,,,HPO,-1.231,0.175299,0.000273498,1.02585 beta-lactamase_156_P25H,beta-lactamase_156_25,TEM-1,beta-lactamase_156,P62593,1.02586,NO,25,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.526,-4.604,3.078,,0.624,H,A,0.52,0.14,1.079,,73.08,BOA,-2.15367,0.111618,0.00347571,1.02586 PSD95pdz3_R354A,PSD95pdz3_354,PSD95pdz3,PSD95pdz3,P31016,1.02586,NO,354,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.582,-2.759,1.177,6.21887,,,,,23.7791,,,,HBB,-1.44833,0.0758425,0.000650924,1.02586 beta-lactamase_0_K213E,beta-lactamase_0_213,TEM-1,beta-lactamase_0,P62593,1.02587,NO,213,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.81,-2.688,0.878,,0.67,,A,2.34,0.29,3.015,,67.83,ABH,-1.57767,0.0500837,0.00610411,1.02587 beta-lactamase_625_Q204N,beta-lactamase_625_204,TEM-1,beta-lactamase_625,P62593,1.02587,NO,204,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-1.382,-3.623,2.241,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.213352,0.00364106,1.02587 beta-lactamase_156_V29F,beta-lactamase_156_29,TEM-1,beta-lactamase_156,P62593,1.02588,NO,29,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-2.856,-4.364,1.508,,0.733,H,A,0.44,-0.78,3.685,,93.01,HHB,-2.24733,0.111618,0.00318969,1.02588 beta-lactamase_39_I277F,beta-lactamase_39_277,TEM-1,beta-lactamase_39,P62593,1.02588,NO,277,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.0495842,0.0169305,1.02588 beta-lactamase_N152E,beta-lactamase_152,TEM-1,beta-lactamase,P62593,1.02588,NO,152,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-2.757,-2.679,-0.078,5.98571,0.863,H,A,0.09,0.92,2.061,,77.62,BPH,-2.97,0.221079,0.00471429,1.02588 beta-lactamase_S201H,beta-lactamase_201,TEM-1,beta-lactamase,P62593,1.02588,NO,201,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.183,-4.595,3.412,4.85496,0.064,H,A,0.77,-0.07,4.045,,64.69,HPB,-1.451,0.221079,0.00198815,1.02588 beta-lactamase_39_K109R,beta-lactamase_39_109,TEM-1,beta-lactamase_39,P62593,1.02589,NO,109,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.734,-2.595,0.861,,0.787,G,A,2.34,2.21,7.243,,72.73,ABB,-1.63333,0.0495842,0.00462493,1.02589 PSD95pdz3_K393Y,PSD95pdz3_393,PSD95pdz3,PSD95pdz3,P31016,1.02589,NO,393,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.416,,,5.42682,,,,,22.0122,,,,HBO,-1.4265,0.0758425,0.000879298,1.02589 beta-lactamase_625_F58M,beta-lactamase_625_58,TEM-1,beta-lactamase_625,P62593,1.02593,NO,58,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-2.914,-4.667,1.753,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.213352,0.00523369,1.02593 beta-lactamase_625_T112K,beta-lactamase_625_112,TEM-1,beta-lactamase_625,P62593,1.02593,NO,112,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.186,-2.704,0.518,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.213352,0.00531334,1.02593 beta-lactamase_F14F,beta-lactamase_14,TEM-1,beta-lactamase,P62593,1.02593,NO,14,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-2.736,-2.736,,,,,,,,1.537,,93.01,HHH,-2.26133,0.221079,0.00277095,1.02593 beta-lactamase_0_I45C,beta-lactamase_0_45,TEM-1,beta-lactamase_0,P62593,1.02598,NO,45,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-2.421,-4.903,2.482,,,E,B,0.48,-0.3,1.375,,77.62,HHA,-2.30267,0.0500837,0.00452842,1.02598 beta-lactamase_39_P255T,beta-lactamase_39_255,TEM-1,beta-lactamase_39,P62593,1.02599,NO,255,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.0495842,0.00499612,1.02599 PSD95pdz3_G383H,PSD95pdz3_383,PSD95pdz3,PSD95pdz3,P31016,1.02599,NO,383,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.008,-4.362,3.354,5.17213,,,,,20.5325,,,,HOP,-1.338,0.0758425,0.000233044,1.02599 beta-lactamase_156_H110K,beta-lactamase_156_110,TEM-1,beta-lactamase_156,P62593,1.026,NO,110,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-1.706,-2.755,1.049,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.111618,0.00441499,1.026 beta-lactamase_2500_Q88Y,beta-lactamase_2500_88,TEM-1,beta-lactamase_2500,P62593,1.026,NO,88,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.086,-4.349,2.263,,0.807,,B,0.64,2.03,1.84,,77.62,APH,-1.53433,0.361275,0.00504167,1.026 beta-lactamase_M180S,beta-lactamase_180,TEM-1,beta-lactamase,P62593,1.026,NO,180,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-2.795,-2.032,-0.763,4.96809,0.242,,B,1.07,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.221079,0.00552048,1.026 PSD95pdz3_K355S,PSD95pdz3_355,PSD95pdz3,PSD95pdz3,P31016,1.026,NO,355,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.416,-2.842,1.426,5.56865,,,,,17.2556,,,,BBO,-1.33533,0.0758425,0.00063703,1.026 beta-lactamase_625_I285R,beta-lactamase_625_285,TEM-1,beta-lactamase_625,P62593,1.02603,NO,285,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.213352,0.101555,1.02603 beta-lactamase_625_W208L,beta-lactamase_625_208,TEM-1,beta-lactamase_625,P62593,1.02604,NO,208,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-0.818,-3.358,2.54,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.213352,0.00126609,1.02604 kka2_1:8_L126Q,kka2_1:8_126,Kka2,kka2_1:8,P00552,1.02605,NO,126,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.246,-3.15,1.904,,0.285,S,B,1.59,0.12,4.443,,51.89,PHA,-1.744,0.100394,0.0066485,1.02605 kka2_1:8_L126Q,kka2_1:8_126,Kka2,kka2_1:8,P00552,1.02605,NO,126,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.246,-3.15,1.904,,0.285,S,B,1.59,0.12,4.443,,51.89,PHA,-1.744,0.100394,0.0066485,1.02605 beta-lactamase_625_A211H,beta-lactamase_625_211,TEM-1,beta-lactamase_625,P62593,1.02608,NO,211,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.896,-3.336,1.44,,0.369,T,A,0.46,-0.69,2.061,,77.62,AHA,-1.94633,0.213352,0.00648183,1.02608 gb1_Q228V,gb1_228,gb1,gb1,P06654,1.02609,NO,228,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,,,,,,,,,,,,,OPH,-1.282,0.177985,0.00391043,1.02609 gb1_T275A,gb1_275,gb1,gb1,P06654,1.02609,NO,275,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.727,-2.815,1.088,,,,,,,0.511,,35.71,HPB,-1.637,0.177985,0.00606618,1.02609 beta-lactamase_0_Q204L,beta-lactamase_0_204,TEM-1,beta-lactamase_0,P62593,1.0261,NO,204,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-1.382,-2.716,1.334,,0.204,H,A,0.64,0.09,2.646,,66.08,PPH,-1.49067,0.0500837,0.00364106,1.0261 beta-lactamase_39_K109A,beta-lactamase_39_109,TEM-1,beta-lactamase_39,P62593,1.0261,NO,109,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.734,-3.283,1.549,,0.787,G,A,2.34,2.21,7.243,,72.73,ABB,-1.63333,0.0495842,0.00462493,1.0261 beta-lactamase_0_K30E,beta-lactamase_0_30,TEM-1,beta-lactamase_0,P62593,1.02611,NO,30,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-2.307,-2.686,0.379,,0.142,H,A,2.34,-0.65,1.491,,93.01,HBH,-2.32833,0.0500837,0.00448593,1.02611 beta-lactamase_39_A124I,beta-lactamase_39_124,TEM-1,beta-lactamase_39,P62593,1.02611,NO,124,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.181,-3.529,2.348,,,H,A,0.46,-0.9,1.367,,64.34,HHH,-1.152,0.0495842,0.00481399,1.02611 kka2_1:8_A64R,kka2_1:8_64,Kka2,kka2_1:8,P00552,1.02611,NO,64,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.496,-4.086,2.59,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.100394,0.00705578,1.02611 kka2_1:8_A64R,kka2_1:8_64,Kka2,kka2_1:8,P00552,1.02611,NO,64,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.496,-4.086,2.59,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.100394,0.00705578,1.02611 kka2_1:8_Q61H,kka2_1:8_61,Kka2,kka2_1:8,P00552,1.02611,NO,61,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.982,-4.796,1.814,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.100394,0.00612092,1.02611 kka2_1:8_Q61H,kka2_1:8_61,Kka2,kka2_1:8,P00552,1.02611,NO,61,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.982,-4.796,1.814,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.100394,0.00612092,1.02611 beta-lactamase_39_A211K,beta-lactamase_39_211,TEM-1,beta-lactamase_39,P62593,1.02612,NO,211,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.896,-3.538,1.642,,0.369,T,A,0.46,-0.69,1.419,,77.62,AHA,-1.94633,0.0495842,0.00648183,1.02612 PSD95pdz3_V315M,PSD95pdz3_315,PSD95pdz3,PSD95pdz3,P31016,1.02614,NO,315,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.625,-3.8,2.175,5.52024,,,,,18.4557,4.054,,81.35,HHH,-1.62767,0.0758425,0.00153536,1.02614 beta-lactamase_156_L197R,beta-lactamase_156_197,TEM-1,beta-lactamase_156,P62593,1.02617,NO,197,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.853,-3.93,3.077,,0.007,S,B,0.55,0.33,1.58,,60.14,HHP,-1.833,0.111618,0.00144602,1.02617 PSD95pdz3_G335F,PSD95pdz3_335,PSD95pdz3,PSD95pdz3,P31016,1.02618,NO,335,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.008,-3.974,2.966,4.76223,,,,,22.4225,,,,AOH,-1.34733,0.0758425,0.000900493,1.02618 PSD95pdz3_D348S,PSD95pdz3_348,PSD95pdz3,PSD95pdz3,P31016,1.02619,NO,348,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.264,-2.842,1.578,5.02473,,,,,16.8925,,,,HAH,-1.306,0.0758425,0.000731866,1.02619 beta-lactamase_39_L55W,beta-lactamase_39_55,TEM-1,beta-lactamase_39,P62593,1.02621,NO,55,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.86,-2.099,0.239,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.0495842,0.00403741,1.02621 beta-lactamase_39_M67D,beta-lactamase_39_67,TEM-1,beta-lactamase_39,P62593,1.02622,NO,67,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-2.231,-3.779,1.548,,0.006,G,P,0.55,-0.81,1.463,,65.03,HHP,-1.502,0.0495842,0.00409753,1.02622 beta-lactamase_39_R242K,beta-lactamase_39_242,TEM-1,beta-lactamase_39,P62593,1.02622,NO,242,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.0495842,0.00452879,1.02622 beta-lactamase_625_T112W,beta-lactamase_625_112,TEM-1,beta-lactamase_625,P62593,1.02622,NO,112,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.186,-5.474,3.288,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.213352,0.00531334,1.02622 kka2_1:2_A137Q,kka2_1:2_137,Kka2,kka2_1:2,P00552,1.02623,NO,137,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.156,-4.203,2.047,,0.029,H,A,0.46,0.34,1.323,,63.26,PHB,-2.559,0.295029,0.00515054,1.02623 beta-lactamase_V29G,beta-lactamase_29,TEM-1,beta-lactamase,P62593,1.02624,NO,29,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-2.856,-2.66,-0.196,5.58481,0.733,H,A,0.23,-0.78,1.287,,93.01,HHB,-2.24733,0.221079,0.00318969,1.02624 PSD95pdz3_L360H,PSD95pdz3_360,PSD95pdz3,PSD95pdz3,P31016,1.02624,NO,360,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.431,-4.586,3.155,5.09284,,,,,14.2425,1.419,,86.88,HHP,-1.52667,0.0758425,0.000770471,1.02624 beta-lactamase_625_E26C,beta-lactamase_625_26,TEM-1,beta-lactamase_625,P62593,1.02625,NO,26,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.454,-5.02,2.566,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.213352,0.00297948,1.02625 kka2_1:8_H8A,kka2_1:8_8,Kka2,kka2_1:8,P00552,1.02626,NO,8,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-2.759,-1.998,-0.761,,,,,,,,,71.59,HBH,-2.25467,0.100394,0.00256422,1.02626 kka2_1:8_H8A,kka2_1:8_8,Kka2,kka2_1:8,P00552,1.02626,NO,8,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-2.759,-1.998,-0.761,,,,,,,,,71.59,HBH,-2.25467,0.100394,0.00256422,1.02626 PSD95pdz3_A370E,PSD95pdz3_370,PSD95pdz3,PSD95pdz3,P31016,1.02626,NO,370,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.307,-3.122,1.815,5.22304,,,,,17.284,,,,PHP,-1.57967,0.0758425,0.000429106,1.02626 beta-lactamase_0_R273G,beta-lactamase_0_273,TEM-1,beta-lactamase_0,P62593,1.02627,NO,273,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.314,-2.465,0.151,,0.564,H,A,1.2,1.57,20.248,20.248,73.78,ABP,-1.841,0.0500837,0.0077952,1.02627 beta-lactamase_625_D113E,beta-lactamase_625_113,TEM-1,beta-lactamase_625,P62593,1.02628,NO,113,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.829,-2.32,0.491,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.213352,0.00474112,1.02628 beta-lactamase_625_P25H,beta-lactamase_625_25,TEM-1,beta-lactamase_625,P62593,1.02628,NO,25,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.526,-4.604,3.078,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.213352,0.00347571,1.02628 beta-lactamase_625_P25K,beta-lactamase_625_25,TEM-1,beta-lactamase_625,P62593,1.02628,NO,25,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.526,-3.426,1.9,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.213352,0.00347571,1.02628 beta-lactamase_156_D212E,beta-lactamase_156_212,TEM-1,beta-lactamase_156,P62593,1.02629,NO,212,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.624,-3.306,1.682,,0.037,,b,0.75,-0.58,20.222,20.222,74.48,HAB,-1.77667,0.111618,0.00644302,1.02629 kka2_1:4_L259M,kka2_1:4_259,Kka2,kka2_1:4,P00552,1.02629,NO,259,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.088,-2.71,1.622,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.168804,0.0206964,1.02629 beta-lactamase_0_T264K,beta-lactamase_0_264,TEM-1,beta-lactamase_0,P62593,1.0263,NO,264,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.0500837,0.0119399,1.0263 beta-lactamase_156_I277C,beta-lactamase_156_277,TEM-1,beta-lactamase_156,P62593,1.0263,NO,277,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.111618,0.0169305,1.0263 beta-lactamase_39_L55N,beta-lactamase_39_55,TEM-1,beta-lactamase_39,P62593,1.0263,NO,55,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.86,-4.216,2.356,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.0495842,0.00403741,1.0263 beta-lactamase_H151W,beta-lactamase_151,TEM-1,beta-lactamase,P62593,1.02631,NO,151,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-2.96,-5.334,2.374,5.47408,0.594,H,A,0.35,0.1,1.843,,77.62,HBP,-2.34767,0.221079,0.00216946,1.02631 beta-lactamase_R118N,beta-lactamase_118,TEM-1,beta-lactamase,P62593,1.02631,NO,118,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.413,-3.711,1.298,5.8227,0.457,H,A,0.68,1.39,2.144,,77.62,HBA,-1.785,0.221079,0.00538794,1.02631 beta-lactamase_T112E,beta-lactamase_112,TEM-1,beta-lactamase,P62593,1.02631,NO,112,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.186,-2.494,0.308,6.47162,0.921,T,A,0.77,1.06,2.04,,73.78,HPA,-1.925,0.221079,0.00531334,1.02631 beta-lactamase_2500_V260I,beta-lactamase_2500_260,TEM-1,beta-lactamase_2500,P62593,1.02632,NO,260,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.361275,0.00471757,1.02632 beta-lactamase_156_F228Q,beta-lactamase_156_228,TEM-1,beta-lactamase_156,P62593,1.02633,NO,228,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-2.342,-2.674,0.332,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.111618,0.0046669,1.02633 beta-lactamase_0_E279V,beta-lactamase_0_279,TEM-1,beta-lactamase_0,P62593,1.02637,NO,279,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.0500837,0.0192826,1.02637 beta-lactamase_0_V157W,beta-lactamase_0_157,TEM-1,beta-lactamase_0,P62593,1.02637,NO,157,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.751,-5.264,3.513,,0.308,S,a,0.44,-0.75,3.106,,69.58,BHP,-2.00767,0.0500837,0.00506849,1.02637 beta-lactamase_39_P143V,beta-lactamase_39_143,TEM-1,beta-lactamase_39,P62593,1.0264,NO,143,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.967,-3.311,2.344,,0.075,H,A,0.52,-0.37,0.976,,66.78,OOB,-1.354,0.0495842,0.00114551,1.0264 PSD95pdz3_N381S,PSD95pdz3_381,PSD95pdz3,PSD95pdz3,P31016,1.0264,NO,381,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-1.41,-2.617,1.207,5.66057,,,,,28.2162,,,,BPH,-1.37767,0.0758425,0.000265374,1.0264 beta-lactamase_39_T126N,beta-lactamase_39_126,TEM-1,beta-lactamase_39,P62593,1.02641,NO,126,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.122,-3.467,2.345,,0.05,H,A,0.22,-0.05,0.586,,44.41,HPH,-1.60467,0.0495842,0.00244552,1.02641 kka2_1:8_E169N,kka2_1:8_169,Kka2,kka2_1:8,P00552,1.02641,NO,169,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.996,-3.126,1.13,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.100394,0.00730086,1.02641 kka2_1:8_E169N,kka2_1:8_169,Kka2,kka2_1:8,P00552,1.02641,NO,169,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.996,-3.126,1.13,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.100394,0.00730086,1.02641 Pab1_P200R,Pab1_200,Pab1,Pab1,P04147,1.02641,NO,200,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.871,-3.639,1.768,,,,,,,3.877,,80.59,HOO,-1.7005,0.175299,0.00190795,1.02641 kka2_1:2_E160C,kka2_1:2_160,Kka2,kka2_1:2,P00552,1.02642,NO,160,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.683,-5.219,3.536,,0.989,G,A,1.04,2.28,3.948,,71.59,AAA,-1.36133,0.295029,0.00935762,1.02642 beta-lactamase_39_G216Y,beta-lactamase_39_216,TEM-1,beta-lactamase_39,P62593,1.02646,NO,216,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.477,-4.44,2.963,,0.437,I,A,0.29,-0.58,0.834,,74.48,HOO,-1.68067,0.0495842,0.00639568,1.02646 beta-lactamase_39_S221M,beta-lactamase_39_221,TEM-1,beta-lactamase_39,P62593,1.02646,NO,221,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.754,-4.595,2.841,,0.624,H,A,0.27,-0.2,2.69,,74.48,BPH,-1.59967,0.0495842,0.0046094,1.02646 beta-lactamase_39_I245V,beta-lactamase_39_245,TEM-1,beta-lactamase_39,P62593,1.02648,NO,245,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.0495842,0.00391032,1.02648 kka2_1:4_T85N,kka2_1:4_85,Kka2,kka2_1:4,P00552,1.02648,NO,85,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.165,-3.801,1.636,,0.576,E,B,0.22,1.39,1.853,,71.59,HPA,-2.10133,0.168804,0.00634493,1.02648 beta-lactamase_625_A215S,beta-lactamase_625_215,TEM-1,beta-lactamase_625,P62593,1.02649,NO,215,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.503,-2.232,0.729,,,,a,0.46,-0.93,3.583,,74.48,HHO,-1.42633,0.213352,0.00544007,1.02649 beta-lactamase_625_V29Y,beta-lactamase_625_29,TEM-1,beta-lactamase_625,P62593,1.02649,NO,29,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-2.856,-4.329,1.473,,0.733,H,A,0.44,-0.78,1.931,,93.01,HHB,-2.24733,0.213352,0.00318969,1.02649 beta-lactamase_156_S122V,beta-lactamase_156_122,TEM-1,beta-lactamase_156,P62593,1.0265,NO,122,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.406,-2.967,0.561,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.111618,0.00497825,1.0265 beta-lactamase_39_P143D,beta-lactamase_39_143,TEM-1,beta-lactamase_39,P62593,1.0265,NO,143,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.967,-3.622,2.655,,0.075,H,A,0.52,-0.37,0.976,,66.78,OOB,-1.354,0.0495842,0.00114551,1.0265 beta-lactamase_39_E238D,beta-lactamase_39_238,TEM-1,beta-lactamase_39,P62593,1.02651,NO,238,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.0495842,0.00743256,1.02651 beta-lactamase_R41H,beta-lactamase_41,TEM-1,beta-lactamase,P62593,1.02651,NO,41,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-0.942,-4.279,3.337,5.69185,0.321,E,B,0.91,-0.07,4.357,,65.03,HBH,-1.30267,0.221079,0.00123327,1.02651 beta-lactamase_A200D,beta-lactamase_200,TEM-1,beta-lactamase,P62593,1.02652,NO,200,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.878,-2.929,1.051,5.19406,0.757,H,A,0.47,-0.19,0.436,,77.62,HHP,-2.001,0.221079,0.0060056,1.02652 beta-lactamase_T138A,beta-lactamase_138,TEM-1,beta-lactamase,P62593,1.02652,NO,138,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.506,-2.248,-0.258,5.52585,0.662,H,A,0.3,-0.03,30.445,30.445,73.78,HPP,-1.81233,0.221079,0.00487868,1.02652 beta-lactamase_39_A200C,beta-lactamase_39_200,TEM-1,beta-lactamase_39,P62593,1.02653,NO,200,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.878,-5.005,3.127,,0.757,H,A,0.46,-0.19,1.54,,77.62,HHP,-2.001,0.0495842,0.0060056,1.02653 beta-lactamase_39_E46L,beta-lactamase_39_46,TEM-1,beta-lactamase_39,P62593,1.02653,NO,46,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.94,-2.216,0.276,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.0495842,0.00427568,1.02653 beta-lactamase_625_K190H,beta-lactamase_625_190,TEM-1,beta-lactamase_625,P62593,1.02653,NO,190,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.994,-3.068,1.074,,0.371,H,A,2.34,0.16,29.753,29.753,77.62,BBH,-1.64167,0.213352,0.00574527,1.02653 beta-lactamase_2500_I277F,beta-lactamase_2500_277,TEM-1,beta-lactamase_2500,P62593,1.02654,NO,277,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.361275,0.0169305,1.02654 beta-lactamase_39_K109G,beta-lactamase_39_109,TEM-1,beta-lactamase_39,P62593,1.02655,NO,109,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.734,-2.852,1.118,,0.787,G,A,2.34,2.21,7.243,,72.73,ABB,-1.63333,0.0495842,0.00462493,1.02655 beta-lactamase_0_T116W,beta-lactamase_0_116,TEM-1,beta-lactamase_0,P62593,1.02656,NO,116,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.28,-5.356,4.076,,0.115,E,B,0.22,-0.12,1.356,,67.48,HPH,-1.39967,0.0500837,0.00336175,1.02656 beta-lactamase_0_N168R,beta-lactamase_0_168,TEM-1,beta-lactamase_0,P62593,1.02659,NO,168,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-1.029,-3.58,2.551,,0.113,G,A,0.61,-0.4,0.881,,44.41,HPA,-1.13233,0.0500837,0.00288667,1.02659 beta-lactamase_39_A148K,beta-lactamase_39_148,TEM-1,beta-lactamase_39,P62593,1.02659,NO,148,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.757,-2.857,1.1,,0.379,H,A,0.46,-0.55,3.551,,72.73,PHH,-1.40167,0.0495842,0.00547053,1.02659 beta-lactamase_39_A235I,beta-lactamase_39_235,TEM-1,beta-lactamase_39,P62593,1.0266,NO,235,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.266,-3.683,2.417,,0.32,E,B,0.46,-0.86,1.344,,50,OHO,-0.89,0.0495842,0.00493474,1.0266 beta-lactamase_156_A211C,beta-lactamase_156_211,TEM-1,beta-lactamase_156,P62593,1.02662,NO,211,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.896,-5.066,3.17,,0.369,T,A,0.46,-0.69,8.527,8.527,77.62,AHA,-1.94633,0.111618,0.00648183,1.02662 beta-lactamase_39_T112F,beta-lactamase_39_112,TEM-1,beta-lactamase_39,P62593,1.02662,NO,112,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.186,-4.382,2.196,,0.921,T,A,0.22,1.06,2.87,,73.78,HPA,-1.925,0.0495842,0.00531334,1.02662 beta-lactamase_625_E195S,beta-lactamase_625_195,TEM-1,beta-lactamase_625,P62593,1.02665,NO,195,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.186,-2.512,0.326,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.213352,0.00496565,1.02665 beta-lactamase_625_L191M,beta-lactamase_625_191,TEM-1,beta-lactamase_625,P62593,1.02665,NO,191,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.087,-4.016,2.929,,,H,A,0.55,0.09,1.908,,63.29,BHH,-1.445,0.213352,0.00263549,1.02665 PSD95pdz3_L342H,PSD95pdz3_342,PSD95pdz3,PSD95pdz3,P31016,1.02665,NO,342,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.347,-4.587,3.24,5.03015,,,,,12.0762,,,,HHH,-1.428,0.0758425,0.00081112,1.02665 beta-lactamase_625_I45L,beta-lactamase_625_45,TEM-1,beta-lactamase_625,P62593,1.02666,NO,45,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-2.421,-2.39,-0.031,,,E,B,0.48,-0.3,3.642,,77.62,HHA,-2.30267,0.213352,0.00452842,1.02666 beta-lactamase_0_E108N,beta-lactamase_0_108,TEM-1,beta-lactamase_0,P62593,1.02667,NO,108,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.46,-3.593,2.133,,0.572,G,A,1.04,1.87,8.602,8.602,72.73,PAB,-1.437,0.0500837,0.00413372,1.02667 beta-lactamase_39_S201I,beta-lactamase_39_201,TEM-1,beta-lactamase_39,P62593,1.02667,NO,201,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.183,-3.765,2.582,,0.064,H,A,0.27,-0.07,3.54,,64.69,HPB,-1.451,0.0495842,0.00198815,1.02667 kka2_1:8_L81M,kka2_1:8_81,Kka2,kka2_1:8,P00552,1.02667,NO,81,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.427,-2.896,1.469,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.100394,0.00805839,1.02667 kka2_1:8_L81M,kka2_1:8_81,Kka2,kka2_1:8,P00552,1.02667,NO,81,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.427,-2.896,1.469,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.100394,0.00805839,1.02667 beta-lactamase_625_I54H,beta-lactamase_625_54,TEM-1,beta-lactamase_625,P62593,1.02668,NO,54,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-2.838,-3.42,0.582,,0.669,E,B,0.48,-0.14,3.946,,73.78,BHH,-2.337,0.213352,0.00403589,1.02668 beta-lactamase_39_I125T,beta-lactamase_39_125,TEM-1,beta-lactamase_39,P62593,1.02669,NO,125,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.441,-2.752,1.311,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.0495842,0.00383964,1.02669 beta-lactamase_625_K109F,beta-lactamase_625_109,TEM-1,beta-lactamase_625,P62593,1.02669,NO,109,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.734,-4.437,2.703,,0.787,G,A,2.34,2.21,7.243,,72.73,ABB,-1.63333,0.213352,0.00462493,1.02669 kka2_1:4_A25G,kka2_1:4_25,Kka2,kka2_1:4,P00552,1.02669,NO,25,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.496,-3.533,1.037,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.168804,0.00595636,1.02669 kka2_1:8_V49T,kka2_1:8_49,Kka2,kka2_1:8,P00552,1.0267,NO,49,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.614,-3.462,1.848,,,E,B,1.48,-0.77,1.31,,64.39,HHB,-1.3,0.100394,0.00615685,1.0267 kka2_1:8_V49T,kka2_1:8_49,Kka2,kka2_1:8,P00552,1.0267,NO,49,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.614,-3.462,1.848,,,E,B,1.48,-0.77,1.31,,64.39,HHB,-1.3,0.100394,0.00615685,1.0267 beta-lactamase_39_G253I,beta-lactamase_39_253,TEM-1,beta-lactamase_39,P62593,1.02672,NO,253,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.0495842,0.00786358,1.02672 beta-lactamase_A15M,beta-lactamase_15,TEM-1,beta-lactamase,P62593,1.02673,NO,15,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.654,-4.395,2.741,,,,,,,31.998,31.998,93.01,HHH,-2.10833,0.221079,0.00248966,1.02673 kka2_1:8_R66C,kka2_1:8_66,Kka2,kka2_1:8,P00552,1.02673,NO,66,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-0.922,-5.15,4.228,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.100394,0.00161025,1.02673 kka2_1:8_R66C,kka2_1:8_66,Kka2,kka2_1:8,P00552,1.02673,NO,66,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-0.922,-5.15,4.228,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.100394,0.00161025,1.02673 PSD95pdz3_D366C,PSD95pdz3_366,PSD95pdz3,PSD95pdz3,P31016,1.02673,NO,366,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.264,-4.769,3.505,5.55684,,,,,20.2375,,,,HAH,-1.401,0.0758425,0.000481272,1.02673 beta-lactamase_156_A170I,beta-lactamase_156_170,TEM-1,beta-lactamase_156,P62593,1.02674,NO,170,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.237,-3.643,2.406,,0.126,,L,0.46,-0.35,3.7,,64.69,AHH,-1.63267,0.111618,0.00431903,1.02674 beta-lactamase_156_I280F,beta-lactamase_156_280,TEM-1,beta-lactamase_156,P62593,1.02674,NO,280,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.111618,0.0530888,1.02674 beta-lactamase_156_A222D,beta-lactamase_156_222,TEM-1,beta-lactamase_156,P62593,1.02676,NO,222,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.103,-3.723,1.62,,0.233,H,A,0.46,-0.25,2.461,,77.62,PHH,-1.63733,0.111618,0.00466094,1.02676 beta-lactamase_39_E238C,beta-lactamase_39_238,TEM-1,beta-lactamase_39,P62593,1.02676,NO,238,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.0495842,0.00743256,1.02676 beta-lactamase_625_E272G,beta-lactamase_625_272,TEM-1,beta-lactamase_625,P62593,1.02677,NO,272,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.213352,0.00545371,1.02677 beta-lactamase_0_T139M,beta-lactamase_0_139,TEM-1,beta-lactamase_0,P62593,1.02678,NO,139,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.901,-4.659,2.758,,0.216,H,A,0.22,0.39,0.421,,77.62,PPH,-2.04667,0.0500837,0.00441837,1.02678 beta-lactamase_39_I93W,beta-lactamase_39_93,TEM-1,beta-lactamase_39,P62593,1.02679,NO,93,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.401,-5.418,4.017,,0.128,E,B,0.48,0.44,1.757,,67.83,BHB,-1.873,0.0495842,0.00527066,1.02679 beta-lactamase_D207S,beta-lactamase_207,TEM-1,beta-lactamase,P62593,1.02679,NO,207,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.064,-2.656,0.592,5.40404,0.409,H,A,0.23,0.12,1.975,,77.62,HAH,-1.77033,0.221079,0.00592942,1.02679 beta-lactamase_L192I,beta-lactamase_192,TEM-1,beta-lactamase,P62593,1.02679,NO,192,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.254,-2.519,1.265,5.68899,0.095,H,A,1.3,0.35,1.756,,60.14,HHP,-1.41833,0.221079,0.00558728,1.02679 beta-lactamase_T112W,beta-lactamase_112,TEM-1,beta-lactamase,P62593,1.02679,NO,112,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.186,-5.474,3.288,6.47162,0.921,T,A,0.77,1.06,2.04,,73.78,HPA,-1.925,0.221079,0.00531334,1.02679 PSD95pdz3_I336V,PSD95pdz3_336,PSD95pdz3,PSD95pdz3,P31016,1.0268,NO,336,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.63,-2.085,0.455,5.11321,,,,,13.6363,,,,OHH,-1.38733,0.0758425,0.000887923,1.0268 beta-lactamase_39_G76I,beta-lactamase_39_76,TEM-1,beta-lactamase_39,P62593,1.02681,NO,76,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.189,-3.948,2.759,,,H,A,0.29,-0.67,2.145,,67.83,OOH,-1.22267,0.0495842,0.00476637,1.02681 beta-lactamase_39_S51C,beta-lactamase_39_51,TEM-1,beta-lactamase_39,P62593,1.02682,NO,51,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.526,-4.878,3.352,,0.496,T,A,0.27,0.26,2.964,,72.73,PPO,-1.88467,0.0495842,0.00504821,1.02682 beta-lactamase_2500_K190C,beta-lactamase_2500_190,TEM-1,beta-lactamase_2500,P62593,1.02684,NO,190,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.994,-5.082,3.088,,0.371,H,A,2.34,0.16,29.753,29.753,77.62,BBH,-1.64167,0.361275,0.00574527,1.02684 kka2_1:4_A108R,kka2_1:4_108,Kka2,kka2_1:4,P00552,1.02684,NO,108,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.061,-4.036,1.975,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.168804,0.00751209,1.02684 beta-lactamase_0_E145R,beta-lactamase_0_145,TEM-1,beta-lactamase_0,P62593,1.02686,NO,145,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.357,-2.676,0.319,,0.545,H,A,1.04,0.79,1.199,,77.62,BAH,-2.069,0.0500837,0.00553285,1.02686 beta-lactamase_2500_R118S,beta-lactamase_2500_118,TEM-1,beta-lactamase_2500,P62593,1.02686,NO,118,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.413,-2.394,-0.019,,0.457,H,A,1.2,1.39,2.144,,77.62,HBA,-1.785,0.361275,0.00538794,1.02686 beta-lactamase_H285T,beta-lactamase_285,TEM-1,beta-lactamase,P62593,1.02686,NO,285,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-1.845,-3.505,1.66,5.64289,0.312,T,a,0.35,0.64,1.401,,72.73,BBH,-1.64567,0.221079,0.101555,1.02686 beta-lactamase_156_R162Q,beta-lactamase_156_162,TEM-1,beta-lactamase_156,P62593,1.02688,NO,162,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.016,-3.59,2.574,,0.124,S,B,1.2,-0.37,7.444,,64.69,ABH,-1.25,0.111618,0.000561334,1.02688 kka2_1:1_V83A,kka2_1:1_83,Kka2,kka2_1:1,P00552,1.02689,NO,83,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-2.567,-2.453,-0.114,,0.358,E,B,0.44,0.53,5.931,,71.59,AHH,-2.264,0.520039,0.00650486,1.02689 beta-lactamase_156_T138H,beta-lactamase_156_138,TEM-1,beta-lactamase_156,P62593,1.0269,NO,138,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.506,-4.649,2.143,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.111618,0.00487868,1.0269 beta-lactamase_39_A215D,beta-lactamase_39_215,TEM-1,beta-lactamase_39,P62593,1.02691,NO,215,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.503,-3.621,2.118,,,,a,0.46,-0.93,0.494,,74.48,HHO,-1.42633,0.0495842,0.00544007,1.02691 gb1_K276H,gb1_276,gb1,gb1,P06654,1.02691,NO,276,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.456,-4.192,2.736,,,,,,,0.236,,12.72,PBP,-1.65133,0.177985,0.00620493,1.02691 beta-lactamase_0_M270T,beta-lactamase_0_270,TEM-1,beta-lactamase_0,P62593,1.02692,NO,270,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.0500837,0.00767762,1.02692 beta-lactamase_156_L55K,beta-lactamase_156_55,TEM-1,beta-lactamase_156,P62593,1.02692,NO,55,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.86,-3.791,1.931,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.111618,0.00403741,1.02692 kka2_1:8_L158M,kka2_1:8_158,Kka2,kka2_1:8,P00552,1.02692,NO,158,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.947,-4.254,2.307,,0.095,.,B,0.55,0.77,1.607,,63.64,AHA,-1.25333,0.100394,0.00529068,1.02692 kka2_1:8_L158M,kka2_1:8_158,Kka2,kka2_1:8,P00552,1.02692,NO,158,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.947,-4.254,2.307,,0.095,.,B,0.55,0.77,1.607,,63.64,AHA,-1.25333,0.100394,0.00529068,1.02692 beta-lactamase_0_R239W,beta-lactamase_0_239,TEM-1,beta-lactamase_0,P62593,1.02694,NO,239,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.0500837,0.00213852,1.02694 beta-lactamase_39_L196R,beta-lactamase_39_196,TEM-1,beta-lactamase_39,P62593,1.02694,NO,196,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-2.478,-2.59,0.112,,0.518,S,A,0.55,1.35,12.152,12.152,77.62,AHH,-1.839,0.0495842,0.00512144,1.02694 kka2_1:1_D238Q,kka2_1:1_238,Kka2,kka2_1:1,P00552,1.02694,NO,238,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.83,-2.348,-0.482,,0.604,H,A,0.75,-0.33,11.329,11.329,92.05,HAB,-2.633,0.520039,0.0113863,1.02694 kka2_1:2_G74Q,kka2_1:2_74,Kka2,kka2_1:2,P00552,1.02694,NO,74,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.18,-3.052,1.872,,0.621,T,l,0.75,0.2,1.446,,64.39,POH,-1.91667,0.295029,0.00587035,1.02694 beta-lactamase_39_M66F,beta-lactamase_39_66,TEM-1,beta-lactamase_39,P62593,1.02698,NO,66,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.362,-3.731,2.369,,0.013,,A,0.55,-0.7,1.319,,73.08,OHH,-1.49567,0.0495842,0.00412876,1.02698 beta-lactamase_0_V101L,beta-lactamase_0_101,TEM-1,beta-lactamase_0,P62593,1.02699,NO,101,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.295,-2.095,0.8,,0.342,,B,0.44,0,1.61,,73.08,HHA,-1.54367,0.0500837,0.00374492,1.02699 beta-lactamase_156_A222I,beta-lactamase_156_222,TEM-1,beta-lactamase_156,P62593,1.02701,NO,222,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.103,-3.632,1.529,,0.233,H,A,0.46,-0.25,2.461,,77.62,PHH,-1.63733,0.111618,0.00466094,1.02701 beta-lactamase_156_I261C,beta-lactamase_156_261,TEM-1,beta-lactamase_156,P62593,1.02701,NO,261,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.111618,0.0123091,1.02701 beta-lactamase_A182V,beta-lactamase_182,TEM-1,beta-lactamase,P62593,1.02701,NO,182,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.777,-2.556,0.779,4.98609,0.136,H,A,0.52,-0.66,2.032,,93.01,OHH,-1.27367,0.221079,0.00559099,1.02701 beta-lactamase_156_L284S,beta-lactamase_156_284,TEM-1,beta-lactamase_156,P62593,1.02702,NO,284,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.111618,0.0686156,1.02702 beta-lactamase_156_T131N,beta-lactamase_156_131,TEM-1,beta-lactamase_156,P62593,1.02703,NO,131,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.328,-3.603,2.275,,,H,A,0.22,-0.69,2.031,,67.48,PPH,-1.00867,0.111618,0.00345886,1.02703 beta-lactamase_625_F70A,beta-lactamase_625_70,TEM-1,beta-lactamase_625,P62593,1.02703,NO,70,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.169,-3.227,2.058,,,H,A,0.58,-1.34,1.14,,63.99,PHB,-0.980667,0.213352,0.00193499,1.02703 beta-lactamase_625_T138W,beta-lactamase_625_138,TEM-1,beta-lactamase_625,P62593,1.02704,NO,138,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.506,-5.551,3.045,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.213352,0.00487868,1.02704 gb1_T244C,gb1_244,gb1,gb1,P06654,1.02704,NO,244,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.637,-4.448,2.811,,,,,,,0.202,,11.83,PPA,-1.92567,0.177985,0.00222755,1.02704 beta-lactamase_0_D36K,beta-lactamase_0_36,TEM-1,beta-lactamase_0,P62593,1.02705,NO,36,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.732,-2.543,-0.189,,0.555,H,A,0.75,1.17,13.689,13.689,77.62,AAP,-1.91167,0.0500837,0.00476483,1.02705 beta-lactamase_2500_L150M,beta-lactamase_2500_150,TEM-1,beta-lactamase_2500,P62593,1.02705,NO,150,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.326,-2.392,1.066,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.361275,0.00463171,1.02705 beta-lactamase_W163F,beta-lactamase_163,TEM-1,beta-lactamase,P62593,1.02705,NO,163,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-1.843,-3.138,1.295,6.2765,0.467,,B,1.22,-0.5,3.642,,63.99,BHA,-1.269,0.221079,0.00418955,1.02705 beta-lactamase_156_V106C,beta-lactamase_156_106,TEM-1,beta-lactamase_156,P62593,1.02706,NO,106,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.218,-4.774,3.556,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.111618,0.00304168,1.02706 kka2_1:2_S40R,kka2_1:2_40,Kka2,kka2_1:2,P00552,1.02706,NO,40,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.645,-2.494,-0.151,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.295029,0.00693477,1.02706 kka2_1:8_E160G,kka2_1:8_160,Kka2,kka2_1:8,P00552,1.02706,NO,160,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.683,-3.367,1.684,,0.989,G,A,1.04,2.28,2.164,,71.59,AAA,-1.36133,0.100394,0.00935762,1.02706 kka2_1:8_E160G,kka2_1:8_160,Kka2,kka2_1:8,P00552,1.02706,NO,160,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.683,-3.367,1.684,,0.989,G,A,1.04,2.28,2.164,,71.59,AAA,-1.36133,0.100394,0.00935762,1.02706 beta-lactamase_156_I285R,beta-lactamase_156_285,TEM-1,beta-lactamase_156,P62593,1.02707,NO,285,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.111618,0.101555,1.02707 beta-lactamase_39_R118N,beta-lactamase_39_118,TEM-1,beta-lactamase_39,P62593,1.02707,NO,118,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.413,-3.711,1.298,,0.457,H,A,1.2,1.39,3.961,,77.62,HBA,-1.785,0.0495842,0.00538794,1.02707 beta-lactamase_0_I244H,beta-lactamase_0_244,TEM-1,beta-lactamase_0,P62593,1.02708,NO,244,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.555,-4.957,3.402,,,E,B,0.48,-0.84,1.241,,77.62,OHH,-1.385,0.0500837,0.00605379,1.02708 beta-lactamase_625_E26A,beta-lactamase_625_26,TEM-1,beta-lactamase_625,P62593,1.0271,NO,26,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.454,-2.207,-0.247,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.213352,0.00297948,1.0271 beta-lactamase_625_Q88K,beta-lactamase_625_88,TEM-1,beta-lactamase_625,P62593,1.02711,NO,88,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.086,-2.839,0.753,,0.807,,B,0.64,2.03,1.84,,77.62,APH,-1.53433,0.213352,0.00504167,1.02711 beta-lactamase_39_S201Y,beta-lactamase_39_201,TEM-1,beta-lactamase_39,P62593,1.02712,NO,201,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.183,-4.222,3.039,,0.064,H,A,0.27,-0.07,3.54,,64.69,HPB,-1.451,0.0495842,0.00198815,1.02712 beta-lactamase_625_G141M,beta-lactamase_625_141,TEM-1,beta-lactamase_625,P62593,1.02712,NO,141,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.828,-4.966,4.138,,0.575,T,l,0.29,-0.28,0.198,,64.69,HOO,-1.08933,0.213352,0.0012419,1.02712 beta-lactamase_0_V29R,beta-lactamase_0_29,TEM-1,beta-lactamase_0,P62593,1.02713,NO,29,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-2.856,-3.682,0.826,,0.733,H,A,0.44,-0.78,21.916,21.916,93.01,HHB,-2.24733,0.0500837,0.00318969,1.02713 beta-lactamase_2500_D33Q,beta-lactamase_2500_33,TEM-1,beta-lactamase_2500,P62593,1.02713,NO,33,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.321,-2.638,0.317,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.361275,0.00435556,1.02713 beta-lactamase_39_L197D,beta-lactamase_39_197,TEM-1,beta-lactamase_39,P62593,1.02713,NO,197,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.853,-4.107,3.254,,0.007,S,B,0.55,0.33,1.559,,60.14,HHP,-1.833,0.0495842,0.00144602,1.02713 beta-lactamase_625_E46I,beta-lactamase_625_46,TEM-1,beta-lactamase_625,P62593,1.02714,NO,46,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.94,-2.064,0.124,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.213352,0.00427568,1.02714 PSD95pdz3_R354M,PSD95pdz3_354,PSD95pdz3,PSD95pdz3,P31016,1.02714,NO,354,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.582,-4.162,2.58,6.21887,,,,,23.7791,,,,HBB,-1.44833,0.0758425,0.000650924,1.02714 beta-lactamase_Q274L,beta-lactamase_274,TEM-1,beta-lactamase,P62593,1.02716,NO,274,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.082,-2.366,0.284,5.6671,0.066,H,A,0.11,-0.27,2.354,,64.69,BPH,-1.931,0.221079,0.0110418,1.02716 PSD95pdz3_R312S,PSD95pdz3_312,PSD95pdz3,PSD95pdz3,P31016,1.02716,NO,312,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.582,-3.067,1.485,5.76826,,,,,12.2409,,,,OBB,-1.46667,0.0758425,0.00196255,1.02716 beta-lactamase_0_I277G,beta-lactamase_0_277,TEM-1,beta-lactamase_0,P62593,1.02718,NO,277,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.0500837,0.0169305,1.02718 beta-lactamase_156_A124I,beta-lactamase_156_124,TEM-1,beta-lactamase_156,P62593,1.02718,NO,124,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.181,-3.529,2.348,,,H,A,0.46,-0.9,2.027,,64.34,HHH,-1.152,0.111618,0.00481399,1.02718 kka2_1:8_W91G,kka2_1:8_91,Kka2,kka2_1:8,P00552,1.02718,NO,91,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-1.178,-3.516,2.338,,0.077,E,B,1.51,0.27,2.51,,48.48,AHH,-1.51,0.100394,0.00358653,1.02718 kka2_1:8_W91G,kka2_1:8_91,Kka2,kka2_1:8,P00552,1.02718,NO,91,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-1.178,-3.516,2.338,,0.077,E,B,1.51,0.27,2.51,,48.48,AHH,-1.51,0.100394,0.00358653,1.02718 beta-lactamase_39_S201V,beta-lactamase_39_201,TEM-1,beta-lactamase_39,P62593,1.0272,NO,201,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.183,-3.482,2.299,,0.064,H,A,0.27,-0.07,3.54,,64.69,HPB,-1.451,0.0495842,0.00198815,1.0272 beta-lactamase_0_D36H,beta-lactamase_0_36,TEM-1,beta-lactamase_0,P62593,1.02721,NO,36,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.732,-3.09,0.358,,0.555,H,A,0.75,1.17,13.689,13.689,77.62,AAP,-1.91167,0.0500837,0.00476483,1.02721 beta-lactamase_39_E87Y,beta-lactamase_39_87,TEM-1,beta-lactamase_39,P62593,1.02721,NO,87,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.421,-4.262,2.841,,0.048,,B,1.04,0.92,15.231,15.231,64.69,PAP,-1.969,0.0495842,0.00337888,1.02721 beta-lactamase_625_A183H,beta-lactamase_625_183,TEM-1,beta-lactamase_625,P62593,1.02721,NO,183,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.231,-4.624,3.393,,0.155,H,A,0.46,-0.91,23.859,23.859,77.62,HHH,-1.53367,0.213352,0.00296631,1.02721 beta-lactamase_39_S221V,beta-lactamase_39_221,TEM-1,beta-lactamase_39,P62593,1.02722,NO,221,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.754,-3.416,1.662,,0.624,H,A,0.27,-0.2,2.69,,74.48,BPH,-1.59967,0.0495842,0.0046094,1.02722 kka2_1:8_G99R,kka2_1:8_99,Kka2,kka2_1:8,P00552,1.02723,NO,99,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.596,-3.961,3.365,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.100394,0.00186055,1.02723 kka2_1:8_G99R,kka2_1:8_99,Kka2,kka2_1:8,P00552,1.02723,NO,99,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.596,-3.961,3.365,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.100394,0.00186055,1.02723 beta-lactamase_39_E166G,beta-lactamase_39_166,TEM-1,beta-lactamase_39,P62593,1.02724,NO,166,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.756,-2.741,0.985,,0.508,G,A,1.04,1.05,17.227,17.227,73.08,OAH,-1.42233,0.0495842,0.00512989,1.02724 beta-lactamase_0_F228E,beta-lactamase_0_228,TEM-1,beta-lactamase_0,P62593,1.02726,NO,228,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-2.342,-3.551,1.209,,0.154,E,B,0.58,-0.42,15.504,15.504,63.29,HHH,-1.53033,0.0500837,0.0046669,1.02726 beta-lactamase_156_G114D,beta-lactamase_156_114,TEM-1,beta-lactamase_156,P62593,1.02729,NO,114,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.094,-3.551,2.457,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.111618,0.00224919,1.02729 beta-lactamase_156_A34M,beta-lactamase_156_34,TEM-1,beta-lactamase_156,P62593,1.0273,NO,34,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.059,-4.351,2.292,,,H,A,0.46,-0.54,3.614,,73.78,AHA,-1.74967,0.111618,0.00407913,1.0273 beta-lactamase_Q97R,beta-lactamase_97,TEM-1,beta-lactamase,P62593,1.02731,NO,97,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.072,-2.428,0.356,6.30204,0.823,G,A,1.1,2.42,1.157,,77.62,PPP,-2.43833,0.221079,0.0045116,1.02731 gb1_E268D,gb1_268,gb1,gb1,P06654,1.02731,NO,268,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.918,-2.143,0.225,,,,,,,0.637,,37.28,OAH,-1.59733,0.177985,0.00423953,1.02731 gb1_V280A,gb1_280,gb1,gb1,P06654,1.02731,NO,280,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.764,-1.686,-0.078,,,,,,,0.874,,35.71,PHP,-1.63733,0.177985,0.00321577,1.02731 beta-lactamase_0_L135E,beta-lactamase_0_135,TEM-1,beta-lactamase_0,P62593,1.02732,NO,135,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.002,-3.919,2.917,,0.117,H,A,0.55,-0.58,0.705,,43.71,PHH,-1.03767,0.0500837,0.00244423,1.02732 PSD95pdz3_K355E,PSD95pdz3_355,PSD95pdz3,PSD95pdz3,P31016,1.02733,NO,355,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.416,-2.672,1.256,5.56865,,,,,17.2556,,,,BBO,-1.33533,0.0758425,0.00063703,1.02733 beta-lactamase_156_G194R,beta-lactamase_156_194,TEM-1,beta-lactamase_156,P62593,1.02734,NO,194,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.396,-3.912,2.516,,0.276,S,b,0.29,0.36,1.346,,67.83,POA,-1.832,0.111618,0.00392163,1.02734 beta-lactamase_156_D212C,beta-lactamase_156_212,TEM-1,beta-lactamase_156,P62593,1.02735,NO,212,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.624,-5.061,3.437,,0.037,,b,0.75,-0.58,20.222,20.222,74.48,HAB,-1.77667,0.111618,0.00644302,1.02735 beta-lactamase_39_R220S,beta-lactamase_39_220,TEM-1,beta-lactamase_39,P62593,1.02736,NO,220,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-0.942,-3.349,2.407,,0.295,I,A,1.2,-0.76,1.596,,74.48,HBP,-1.33633,0.0495842,0.00232421,1.02736 beta-lactamase_156_R118Y,beta-lactamase_156_118,TEM-1,beta-lactamase_156,P62593,1.02739,NO,118,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.413,-4.398,1.985,,0.457,H,A,1.2,1.39,2.231,,77.62,HBA,-1.785,0.111618,0.00538794,1.02739 beta-lactamase_39_I277L,beta-lactamase_39_277,TEM-1,beta-lactamase_39,P62593,1.0274,NO,277,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.0495842,0.0169305,1.0274 E1_Ubiquitin_A46D,E1_Ubiquitin_46,Uba1,E1_Ubiquitin,P0CG63,1.02741,NO,46,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.367,-3.57,2.203,,0.398,T,L,,-0.8,,,,HHO,-1.17167,0.18783,0.004233,1.02741 E1_Ubiquitin_F45Q,E1_Ubiquitin_45,Uba1,E1_Ubiquitin,P0CG63,1.02741,NO,45,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.149,-4.166,3.017,,0.26,E,B,,-0.99,,,,HHH,-1.316,0.18783,0.00193245,1.02741 E1_Ubiquitin_K48L,E1_Ubiquitin_48,Uba1,E1_Ubiquitin,P0CG63,1.02741,NO,48,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.219,-3.279,2.06,,0.132,E,B,,-0.28,,,,OBO,-1.109,0.18783,0.00100363,1.02741 PSD95pdz3_Q358F,PSD95pdz3_358,PSD95pdz3,PSD95pdz3,P31016,1.02741,NO,358,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-1.699,-3.974,2.275,5.21282,,,,,14.8844,,,,APH,-1.531,0.0758425,0.000594893,1.02741 beta-lactamase_625_L38D,beta-lactamase_625_38,TEM-1,beta-lactamase_625,P62593,1.02742,NO,38,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.343,-3.97,2.627,,0.088,H,A,0.55,0.2,1.986,,64.34,PHO,-1.78033,0.213352,0.00373244,1.02742 beta-lactamase_625_F58S,beta-lactamase_625_58,TEM-1,beta-lactamase_625,P62593,1.02744,NO,58,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-2.914,-2.895,-0.019,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.213352,0.00523369,1.02744 beta-lactamase_625_Q86Y,beta-lactamase_625_86,TEM-1,beta-lactamase_625,P62593,1.02745,NO,86,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.4,-4.372,1.972,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.213352,0.00450027,1.02745 beta-lactamase_625_P255D,beta-lactamase_625_255,TEM-1,beta-lactamase_625,P62593,1.02746,NO,255,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.213352,0.00499612,1.02746 beta-lactamase_0_V78P,beta-lactamase_0_78,TEM-1,beta-lactamase_0,P62593,1.02747,NO,78,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.459,-4.126,2.667,,,H,A,0.44,-0.47,16.615,16.615,63.64,HHH,-1.17833,0.0500837,0.00492501,1.02747 kka2_1:8_P109A,kka2_1:8_109,Kka2,kka2_1:8,P00552,1.02747,NO,109,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.412,-1.957,0.545,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.100394,0.0070929,1.02747 kka2_1:8_P109A,kka2_1:8_109,Kka2,kka2_1:8,P00552,1.02747,NO,109,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.412,-1.957,0.545,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.100394,0.0070929,1.02747 beta-lactamase_39_I280M,beta-lactamase_39_280,TEM-1,beta-lactamase_39,P62593,1.02749,NO,280,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.0495842,0.0530888,1.02749 PSD95pdz3_G364Q,PSD95pdz3_364,PSD95pdz3,PSD95pdz3,P31016,1.02749,NO,364,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.008,-3.806,2.798,5.53299,,,,,21.28,,,,POH,-1.33667,0.0758425,0.00050942,1.02749 beta-lactamase_156_D271H,beta-lactamase_156_271,TEM-1,beta-lactamase_156,P62593,1.02751,NO,271,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.111618,0.00752082,1.02751 beta-lactamase_39_E272D,beta-lactamase_39_272,TEM-1,beta-lactamase_39,P62593,1.02751,NO,272,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.127,,,,0.081,H,A,0.43,-0.97,12.983,12.983,63.64,AAB,-1.56333,0.0495842,0.00545371,1.02751 beta-lactamase_156_T112M,beta-lactamase_156_112,TEM-1,beta-lactamase_156,P62593,1.02752,NO,112,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.186,-4.812,2.626,,0.921,T,A,0.22,1.06,2.87,,73.78,HPA,-1.925,0.111618,0.00531334,1.02752 kka2_1:2_E199L,kka2_1:2_199,Kka2,kka2_1:2,P00552,1.02752,NO,199,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.234,-3.058,0.824,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.295029,0.00854122,1.02752 beta-lactamase_39_P105M,beta-lactamase_39_105,TEM-1,beta-lactamase_39,P62593,1.02753,NO,105,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.813,-4.702,3.889,,0.226,T,A,0.52,0.8,1.222,,63.29,POH,-1.01533,0.0495842,0.0011981,1.02753 beta-lactamase_625_A225N,beta-lactamase_625_225,TEM-1,beta-lactamase_625,P62593,1.02753,NO,225,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.845,-3.051,1.206,,1,T,B,0.46,-0.38,9.874,9.874,74.48,OHO,-1.39967,0.213352,0.00465057,1.02753 beta-lactamase_39_H151Q,beta-lactamase_39_151,TEM-1,beta-lactamase_39,P62593,1.02755,NO,151,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-2.96,-2.497,-0.463,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.0495842,0.00216946,1.02755 PSD95pdz3_L342A,PSD95pdz3_342,PSD95pdz3,PSD95pdz3,P31016,1.02755,NO,342,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.347,-2.759,1.412,5.03015,,,,,12.0762,,,,HHH,-1.428,0.0758425,0.00081112,1.02755 PSD95pdz3_T385C,PSD95pdz3_385,PSD95pdz3,PSD95pdz3,P31016,1.02755,NO,385,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.533,-4.414,2.881,5.57157,,,,,23.6871,4.527,,87.71,PPH,-1.56567,0.0758425,0.000545119,1.02755 beta-lactamase_156_D99Q,beta-lactamase_156_99,TEM-1,beta-lactamase_156,P62593,1.02757,NO,99,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.191,-2.836,1.645,,0.402,G,A,0.75,0.36,3.529,,64.69,PAH,-1.794,0.111618,0.00305446,1.02757 beta-lactamase_625_E26V,beta-lactamase_625_26,TEM-1,beta-lactamase_625,P62593,1.02759,NO,26,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.454,-2.776,0.322,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.213352,0.00297948,1.02759 beta-lactamase_156_I244V,beta-lactamase_156_244,TEM-1,beta-lactamase_156,P62593,1.0276,NO,244,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.555,-1.239,-0.316,,,E,B,0.48,-0.84,1.325,,77.62,OHH,-1.385,0.111618,0.00605379,1.0276 beta-lactamase_156_R189F,beta-lactamase_156_189,TEM-1,beta-lactamase_156,P62593,1.0276,NO,189,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.844,-4.275,2.431,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.111618,0.0050699,1.0276 beta-lactamase_39_I171D,beta-lactamase_39_171,TEM-1,beta-lactamase_39,P62593,1.0276,NO,171,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-2.431,-3.888,1.457,,0.361,,B,0.48,0.53,16.954,16.954,77.62,HHO,-1.55533,0.0495842,0.00623355,1.0276 beta-lactamase_S122N,beta-lactamase_122,TEM-1,beta-lactamase,P62593,1.02762,NO,122,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.406,-3.042,0.636,4.87767,0.352,H,A,0.73,-0.54,1.581,,77.62,OPH,-1.39767,0.221079,0.00497825,1.02762 PSD95pdz3_K355G,PSD95pdz3_355,PSD95pdz3,PSD95pdz3,P31016,1.02762,NO,355,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.416,-3.04,1.624,5.56865,,,,,17.2556,,,,BBO,-1.33533,0.0758425,0.00063703,1.02762 PSD95pdz3_N363G,PSD95pdz3_363,PSD95pdz3,PSD95pdz3,P31016,1.02762,NO,363,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-1.41,-2.59,1.18,5.23349,,,,,20.7037,,,,HPO,-1.29433,0.0758425,0.000524014,1.02762 Pab1_G167R,Pab1_167,Pab1,Pab1,P04147,1.02765,NO,167,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.223,-3.677,2.454,,0.195,S,g,,0.03,,,,BOH,-1.25133,0.175299,0.00146449,1.02765 PSD95pdz3_N363H,PSD95pdz3_363,PSD95pdz3,PSD95pdz3,P31016,1.02765,NO,363,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-1.41,-3.687,2.277,5.23349,,,,,20.7037,,,,HPO,-1.29433,0.0758425,0.000524014,1.02765 beta-lactamase_39_S80F,beta-lactamase_39_80,TEM-1,beta-lactamase_39,P62593,1.02768,NO,80,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.029,-4.287,2.258,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.0495842,0.00565569,1.02768 beta-lactamase_156_T193H,beta-lactamase_156_193,TEM-1,beta-lactamase_156,P62593,1.02771,NO,193,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.914,-4.78,2.866,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.111618,0.00482669,1.02771 kka2_1:8_E111Y,kka2_1:8_111,Kka2,kka2_1:8,P00552,1.02771,NO,111,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.28,-4.387,2.107,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.100394,0.00746789,1.02771 kka2_1:8_E111Y,kka2_1:8_111,Kka2,kka2_1:8,P00552,1.02771,NO,111,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.28,-4.387,2.107,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.100394,0.00746789,1.02771 beta-lactamase_39_I285A,beta-lactamase_39_285,TEM-1,beta-lactamase_39,P62593,1.02772,NO,285,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.0495842,0.101555,1.02772 beta-lactamase_0_E119Y,beta-lactamase_0_119,TEM-1,beta-lactamase_0,P62593,1.02773,NO,119,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.412,-4.336,2.924,,0.358,H,A,1.04,0.51,3.396,,63.99,BAH,-1.623,0.0500837,0.00386966,1.02773 beta-lactamase_39_Y95W,beta-lactamase_39_95,TEM-1,beta-lactamase_39,P62593,1.02775,NO,95,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-1.715,-3.22,1.505,,0.122,,b,0.21,-0.37,2.341,,77.62,BHP,-2.16167,0.0495842,0.00479449,1.02775 beta-lactamase_156_M270G,beta-lactamase_156_270,TEM-1,beta-lactamase_156,P62593,1.02776,NO,270,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.111618,0.00767762,1.02776 beta-lactamase_39_M67N,beta-lactamase_39_67,TEM-1,beta-lactamase_39,P62593,1.02777,NO,67,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-2.231,-2.235,0.004,,0.006,G,P,0.55,-0.81,1.463,,65.03,HHP,-1.502,0.0495842,0.00409753,1.02777 kka2_1:4_N200K,kka2_1:4_200,Kka2,kka2_1:4,P00552,1.02777,NO,200,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-2.446,-2.694,0.248,,0.756,T,L,0.61,-0.08,1.746,,64.39,APO,-2.08,0.168804,0.00838549,1.02777 kka2_1:4_H139S,kka2_1:4_139,Kka2,kka2_1:4,P00552,1.02778,NO,139,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-2.809,-2.678,-0.131,,0.471,H,A,0.17,0.68,12.761,12.761,63.64,BBB,-2.22,0.168804,0.00734779,1.02778 beta-lactamase_39_S80N,beta-lactamase_39_80,TEM-1,beta-lactamase_39,P62593,1.02779,NO,80,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.029,-2.999,0.97,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.0495842,0.00565569,1.02779 beta-lactamase_0_A246G,beta-lactamase_0_246,TEM-1,beta-lactamase_0,P62593,1.02781,NO,246,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.121,-3.675,1.554,,0.01,E,B,0.46,-1.01,1.201,,73.78,HHH,-1.55633,0.0500837,0.00569458,1.02781 beta-lactamase_0_T131V,beta-lactamase_0_131,TEM-1,beta-lactamase_0,P62593,1.02781,NO,131,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.328,-3.345,2.017,,,H,A,0.22,-0.69,3.306,,67.48,PPH,-1.00867,0.0500837,0.00345886,1.02781 beta-lactamase_625_Q97F,beta-lactamase_625_97,TEM-1,beta-lactamase_625,P62593,1.02782,NO,97,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.072,-4.44,2.368,,0.823,G,A,0.64,2.42,16.954,16.954,77.62,PPP,-2.43833,0.213352,0.0045116,1.02782 beta-lactamase_39_E238F,beta-lactamase_39_238,TEM-1,beta-lactamase_39,P62593,1.02783,NO,238,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.0495842,0.00743256,1.02783 beta-lactamase_156_R273D,beta-lactamase_156_273,TEM-1,beta-lactamase_156,P62593,1.02784,NO,273,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.314,-3.543,1.229,,0.564,H,A,1.2,1.57,20.248,20.248,73.78,ABP,-1.841,0.111618,0.0077952,1.02784 beta-lactamase_625_Q204C,beta-lactamase_625_204,TEM-1,beta-lactamase_625,P62593,1.02784,NO,204,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-1.382,-5.114,3.732,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.213352,0.00364106,1.02784 beta-lactamase_156_G154D,beta-lactamase_156_154,TEM-1,beta-lactamase_156,P62593,1.02785,NO,154,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.823,-2.317,1.494,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.111618,0.00180205,1.02785 beta-lactamase_39_P25W,beta-lactamase_39_25,TEM-1,beta-lactamase_39,P62593,1.02786,NO,25,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.526,-5.419,3.893,,0.624,H,A,0.52,0.14,1.157,,73.08,BOA,-2.15367,0.0495842,0.00347571,1.02786 beta-lactamase_625_A211E,beta-lactamase_625_211,TEM-1,beta-lactamase_625,P62593,1.02786,NO,211,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.896,-2.447,0.551,,0.369,T,A,0.46,-0.69,2.061,,77.62,AHA,-1.94633,0.213352,0.00648183,1.02786 gb1_E245D,gb1_245,gb1,gb1,P06654,1.02786,NO,245,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.725,-3.204,0.479,,,,,,,0.712,,45.54,PAH,-1.84567,0.177985,0.00158611,1.02786 gb1_V255H,gb1_255,gb1,gb1,P06654,1.02786,NO,255,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-3.127,-4.09,0.963,,,,,,,1.323,,45.54,BHH,-2.03867,0.177985,0.00408354,1.02786 beta-lactamase_39_R92S,beta-lactamase_39_92,TEM-1,beta-lactamase_39,P62593,1.02788,NO,92,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.718,-3.47,1.752,,0.479,E,B,1.2,1.36,0.389,,65.38,BBH,-1.50367,0.0495842,0.00429626,1.02788 beta-lactamase_39_S221R,beta-lactamase_39_221,TEM-1,beta-lactamase_39,P62593,1.02788,NO,221,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.754,-2.83,1.076,,0.624,H,A,0.27,-0.2,2.69,,74.48,BPH,-1.59967,0.0495842,0.0046094,1.02788 beta-lactamase_L19L,beta-lactamase_19,TEM-1,beta-lactamase,P62593,1.02788,NO,19,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.682,-1.682,,,,,,,,4.261,,93.01,OHO,-1.894,0.221079,0.00215974,1.02788 beta-lactamase_156_I244M,beta-lactamase_156_244,TEM-1,beta-lactamase_156,P62593,1.02789,NO,244,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.555,-4.138,2.583,,,E,B,0.48,-0.84,1.325,,77.62,OHH,-1.385,0.111618,0.00605379,1.02789 beta-lactamase_39_C75G,beta-lactamase_39_75,TEM-1,beta-lactamase_39,P62593,1.02789,NO,75,C,G,CG,Special,Special,5.07,3.29388,-1.77612,159,121,75,-46,108.5,60.1,-48.4,-1.245,-2.515,1.27,,,H,A,0.46,-0.87,2.369,,50,HOO,-1.24333,0.0495842,0.0034616,1.02789 beta-lactamase_2500_K190V,beta-lactamase_2500_190,TEM-1,beta-lactamase_2500,P62593,1.02791,NO,190,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.994,-2.992,0.998,,0.371,H,A,2.34,0.16,29.753,29.753,77.62,BBH,-1.64167,0.361275,0.00574527,1.02791 beta-lactamase_39_L73Q,beta-lactamase_39_73,TEM-1,beta-lactamase_39,P62593,1.02791,NO,73,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.507,-4.261,2.754,,,H,A,0.55,-0.64,2.09,,67.83,HHH,-1.487,0.0495842,0.00488983,1.02791 beta-lactamase_39_D212G,beta-lactamase_39_212,TEM-1,beta-lactamase_39,P62593,1.02792,NO,212,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.624,-2.198,0.574,,0.037,,b,0.75,-0.58,10.748,10.748,74.48,HAB,-1.77667,0.0495842,0.00644302,1.02792 beta-lactamase_39_P143G,beta-lactamase_39_143,TEM-1,beta-lactamase_39,P62593,1.02793,NO,143,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.967,-3.499,2.532,,0.075,H,A,0.52,-0.37,0.976,,66.78,OOB,-1.354,0.0495842,0.00114551,1.02793 beta-lactamase_39_R41M,beta-lactamase_39_41,TEM-1,beta-lactamase_39,P62593,1.02793,NO,41,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-0.942,-4.506,3.564,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.0495842,0.00123327,1.02793 beta-lactamase_H156K,beta-lactamase_156,TEM-1,beta-lactamase,P62593,1.02794,NO,156,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-3.156,-2.967,-0.189,6.00284,0.753,S,A,0.72,-0.6,6.456,6.456,77.62,ABH,-1.932,0.221079,0.00468596,1.02794 beta-lactamase_M180Q,beta-lactamase_180,TEM-1,beta-lactamase,P62593,1.02794,NO,180,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-2.795,-3.924,1.129,4.96809,0.242,,B,1.07,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.221079,0.00552048,1.02794 beta-lactamase_N50M,beta-lactamase_50,TEM-1,beta-lactamase,P62593,1.02794,NO,50,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-2.979,-4.727,1.748,5.51261,0.912,T,A,1.07,1.24,1.581,,77.62,HPP,-2.134,0.221079,0.0047211,1.02794 beta-lactamase_39_T187L,beta-lactamase_39_187,TEM-1,beta-lactamase_39,P62593,1.02795,NO,187,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.401,-2.278,0.877,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.0495842,0.00491782,1.02795 beta-lactamase_156_T138R,beta-lactamase_156_138,TEM-1,beta-lactamase_156,P62593,1.02796,NO,138,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.506,-2.605,0.099,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.111618,0.00487868,1.02796 beta-lactamase_39_R239H,beta-lactamase_39_239,TEM-1,beta-lactamase_39,P62593,1.02797,NO,239,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.0495842,0.00213852,1.02797 PSD95pdz3_N369R,PSD95pdz3_369,PSD95pdz3,PSD95pdz3,P31016,1.02797,NO,369,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-1.572,-3.344,1.772,5.91569,,,,,24.1262,0.44,,87.71,BPH,-1.487,0.0758425,0.000608412,1.02797 beta-lactamase_0_A235T,beta-lactamase_0_235,TEM-1,beta-lactamase_0,P62593,1.02803,NO,235,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.266,-2.412,1.146,,0.32,E,B,0.46,-0.86,2.261,,50,OHO,-0.89,0.0500837,0.00493474,1.02803 beta-lactamase_156_A182K,beta-lactamase_156_182,TEM-1,beta-lactamase_156,P62593,1.02803,NO,182,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.777,-2.859,1.082,,0.136,H,A,0.46,-0.66,16.784,16.784,93.01,OHH,-1.27367,0.111618,0.00559099,1.02803 kka2_1:8_N200K,kka2_1:8_200,Kka2,kka2_1:8,P00552,1.02803,NO,200,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-2.446,-2.694,0.248,,0.756,T,L,0.43,-0.08,2.528,,64.39,APO,-2.08,0.100394,0.00838549,1.02803 kka2_1:8_N200K,kka2_1:8_200,Kka2,kka2_1:8,P00552,1.02803,NO,200,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-2.446,-2.694,0.248,,0.756,T,L,0.43,-0.08,2.528,,64.39,APO,-2.08,0.100394,0.00838549,1.02803 beta-lactamase_2500_Q88K,beta-lactamase_2500_88,TEM-1,beta-lactamase_2500,P62593,1.02804,NO,88,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.086,-2.839,0.753,,0.807,,B,0.64,2.03,1.84,,77.62,APH,-1.53433,0.361275,0.00504167,1.02804 beta-lactamase_156_L73C,beta-lactamase_156_73,TEM-1,beta-lactamase_156,P62593,1.02805,NO,73,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.507,-4.861,3.354,,,H,A,0.55,-0.64,2.09,,67.83,HHH,-1.487,0.111618,0.00488983,1.02805 beta-lactamase_39_E46N,beta-lactamase_39_46,TEM-1,beta-lactamase_39,P62593,1.02806,NO,46,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.94,-4.011,2.071,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.0495842,0.00427568,1.02806 beta-lactamase_625_V259I,beta-lactamase_625_259,TEM-1,beta-lactamase_625,P62593,1.02807,NO,259,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.522,-1.739,0.217,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.213352,0.0070773,1.02807 beta-lactamase_0_V157A,beta-lactamase_0_157,TEM-1,beta-lactamase_0,P62593,1.02808,NO,157,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.751,-2.656,0.905,,0.308,S,a,0.44,-0.75,3.106,,69.58,BHP,-2.00767,0.0500837,0.00506849,1.02808 beta-lactamase_625_A211Y,beta-lactamase_625_211,TEM-1,beta-lactamase_625,P62593,1.0281,NO,211,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.896,-4.344,2.448,,0.369,T,A,0.46,-0.69,2.061,,77.62,AHA,-1.94633,0.213352,0.00648183,1.0281 PSD95pdz3_E352D,PSD95pdz3_352,PSD95pdz3,PSD95pdz3,P31016,1.0281,NO,352,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.587,-2.842,1.255,5.49659,,,,,24.2,2.525,,86.88,OAH,-1.314,0.0758425,0.000892231,1.0281 PSD95pdz3_E352T,PSD95pdz3_352,PSD95pdz3,PSD95pdz3,P31016,1.0281,NO,352,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.587,-3.102,1.515,5.49659,,,,,24.2,2.525,,86.88,OAH,-1.314,0.0758425,0.000892231,1.0281 beta-lactamase_625_I245V,beta-lactamase_625_245,TEM-1,beta-lactamase_625,P62593,1.02811,NO,245,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.213352,0.00391032,1.02811 kka2_1:2_L7M,kka2_1:2_7,Kka2,kka2_1:2,P00552,1.02812,NO,7,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.926,-2.658,0.732,,,,,,,3.012,,71.59,OHB,-2.12333,0.295029,0.00269456,1.02812 beta-lactamase_39_F70A,beta-lactamase_39_70,TEM-1,beta-lactamase_39,P62593,1.02813,NO,70,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.169,-3.227,2.058,,,H,A,0.58,-1.34,1.14,,63.99,PHB,-0.980667,0.0495842,0.00193499,1.02813 beta-lactamase_0_D33C,beta-lactamase_0_33,TEM-1,beta-lactamase_0,P62593,1.02814,NO,33,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.321,-5.054,2.733,,0.366,H,A,0.75,0.33,12.514,12.514,77.62,BAH,-2.12133,0.0500837,0.00435556,1.02814 beta-lactamase_39_R91H,beta-lactamase_39_91,TEM-1,beta-lactamase_39,P62593,1.02815,NO,91,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.392,-4.422,3.03,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.0495842,0.00380226,1.02815 Pab1_D144T,Pab1_144,Pab1,Pab1,P04147,1.02816,NO,144,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.189,-3.314,2.125,,0.616,H,A,,0.6,,,,HAP,-1.40567,0.175299,0.00121131,1.02816 beta-lactamase_0_I54T,beta-lactamase_0_54,TEM-1,beta-lactamase_0,P62593,1.02817,NO,54,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-2.838,-2.043,-0.795,,0.669,E,B,0.48,-0.14,0.541,,73.78,BHH,-2.337,0.0500837,0.00403589,1.02817 beta-lactamase_156_S201M,beta-lactamase_156_201,TEM-1,beta-lactamase_156,P62593,1.02817,NO,201,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.183,-4.493,3.31,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.111618,0.00198815,1.02817 beta-lactamase_39_A84E,beta-lactamase_39_84,TEM-1,beta-lactamase_39,P62593,1.02818,NO,84,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.651,-2.632,0.981,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.0495842,0.00503822,1.02818 beta-lactamase_39_E46A,beta-lactamase_39_46,TEM-1,beta-lactamase_39,P62593,1.02819,NO,46,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.94,-2.586,0.646,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.0495842,0.00427568,1.02819 Pab1_G177I,Pab1_177,Pab1,Pab1,P04147,1.02821,NO,177,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-2.24,-3.864,1.624,,,,,,,,,,AOH,-1.94067,0.175299,0.00170727,1.02821 beta-lactamase_0_D155R,beta-lactamase_0_155,TEM-1,beta-lactamase_0,P62593,1.02822,NO,155,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.889,-3.873,2.984,,0.049,,B,0.75,-0.9,16.833,16.833,64.69,OAB,-1.62267,0.0500837,0.00135315,1.02822 beta-lactamase_L19I,beta-lactamase_19,TEM-1,beta-lactamase,P62593,1.02822,NO,19,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.682,-3.188,1.506,,,,,,,4.261,,93.01,OHO,-1.894,0.221079,0.00215974,1.02822 beta-lactamase_156_E26P,beta-lactamase_156_26,TEM-1,beta-lactamase_156,P62593,1.02823,NO,26,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.454,-2.862,0.408,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.111618,0.00297948,1.02823 beta-lactamase_39_A200V,beta-lactamase_39_200,TEM-1,beta-lactamase_39,P62593,1.02824,NO,200,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.878,-2.943,1.065,,0.757,H,A,0.46,-0.19,1.54,,77.62,HHP,-2.001,0.0495842,0.0060056,1.02824 beta-lactamase_156_E87Q,beta-lactamase_156_87,TEM-1,beta-lactamase_156,P62593,1.02825,NO,87,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.421,-2.648,1.227,,0.048,,B,1.04,0.92,1.754,,64.69,PAP,-1.969,0.111618,0.00337888,1.02825 beta-lactamase_156_I171H,beta-lactamase_156_171,TEM-1,beta-lactamase_156,P62593,1.02826,NO,171,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-2.431,-4.817,2.386,,0.361,,B,0.48,0.53,3.869,,77.62,HHO,-1.55533,0.111618,0.00623355,1.02826 gb1_T275M,gb1_275,gb1,gb1,P06654,1.02826,NO,275,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.727,-4.304,2.577,,,,,,,0.511,,35.71,HPB,-1.637,0.177985,0.00606618,1.02826 PSD95pdz3_A382T,PSD95pdz3_382,PSD95pdz3,PSD95pdz3,P31016,1.02826,NO,382,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.307,-2.878,1.571,5.30282,,,,,22.472,,,,PHO,-1.24167,0.0758425,0.000249256,1.02826 beta-lactamase_156_E108I,beta-lactamase_156_108,TEM-1,beta-lactamase_156,P62593,1.02827,NO,108,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.46,-4.133,2.673,,0.572,G,A,1.04,1.87,8.602,8.602,72.73,PAB,-1.437,0.111618,0.00413372,1.02827 beta-lactamase_156_E108N,beta-lactamase_156_108,TEM-1,beta-lactamase_156,P62593,1.02827,NO,108,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.46,-3.593,2.133,,0.572,G,A,1.04,1.87,8.602,8.602,72.73,PAB,-1.437,0.111618,0.00413372,1.02827 beta-lactamase_39_E108G,beta-lactamase_39_108,TEM-1,beta-lactamase_39,P62593,1.02827,NO,108,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.46,-2.454,0.994,,0.572,G,A,1.04,1.87,20.151,20.151,72.73,PAB,-1.437,0.0495842,0.00413372,1.02827 beta-lactamase_39_L47N,beta-lactamase_39_47,TEM-1,beta-lactamase_39,P62593,1.02827,NO,47,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.876,-3.972,2.096,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.0495842,0.00439844,1.02827 kka2_1:2_G10A,kka2_1:2_10,Kka2,kka2_1:2,P00552,1.02828,NO,10,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.921,-3.11,1.189,,,,,,,2.192,,71.59,HOP,-2.10733,0.295029,0.00289233,1.02828 beta-lactamase_39_R220W,beta-lactamase_39_220,TEM-1,beta-lactamase_39,P62593,1.02831,NO,220,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-0.942,-5.348,4.406,,0.295,I,A,1.2,-0.76,1.596,,74.48,HBP,-1.33633,0.0495842,0.00232421,1.02831 kka2_1:4_I246Y,kka2_1:4_246,Kka2,kka2_1:4,P00552,1.02832,NO,246,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-2.008,-4.266,2.258,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.168804,0.0139479,1.02832 beta-lactamase_H24A,beta-lactamase_24,TEM-1,beta-lactamase,P62593,1.02834,NO,24,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-2.481,-2.265,-0.216,5.82767,,,,,,2.708,,93.01,HBO,-1.85167,0.221079,0.00238894,1.02834 beta-lactamase_39_L100K,beta-lactamase_39_100,TEM-1,beta-lactamase_39,P62593,1.02836,NO,100,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.218,-3.837,2.619,,0.343,,B,0.55,0.13,8.311,,63.29,AHH,-1.23467,0.0495842,0.00413885,1.02836 beta-lactamase_156_V106D,beta-lactamase_156_106,TEM-1,beta-lactamase_156,P62593,1.02837,NO,106,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.218,-4.056,2.838,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.111618,0.00304168,1.02837 beta-lactamase_625_V29S,beta-lactamase_625_29,TEM-1,beta-lactamase_625,P62593,1.02837,NO,29,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-2.856,-2.693,-0.163,,0.733,H,A,0.44,-0.78,1.931,,93.01,HHB,-2.24733,0.213352,0.00318969,1.02837 beta-lactamase_0_H24I,beta-lactamase_0_24,TEM-1,beta-lactamase_0,P62593,1.02839,NO,24,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-2.481,-3.874,1.393,,,,,,,2.708,,93.01,OBO,-2.0035,0.0500837,0.00238894,1.02839 beta-lactamase_39_L89T,beta-lactamase_39_89,TEM-1,beta-lactamase_39,P62593,1.02839,NO,89,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.096,-3.474,2.378,,0.168,T,A,0.55,0.63,3.233,,64.34,PHO,-1.75767,0.0495842,0.00207068,1.02839 beta-lactamase_156_A282K,beta-lactamase_156_282,TEM-1,beta-lactamase_156,P62593,1.02842,NO,282,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.111618,0.0449821,1.02842 beta-lactamase_156_T138C,beta-lactamase_156_138,TEM-1,beta-lactamase_156,P62593,1.02842,NO,138,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.506,-5.125,2.619,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.111618,0.00487868,1.02842 beta-lactamase_2500_V29M,beta-lactamase_2500_29,TEM-1,beta-lactamase_2500,P62593,1.02842,NO,29,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-2.856,-4.721,1.865,,0.733,H,A,0.44,-0.78,1.931,,93.01,HHB,-2.24733,0.361275,0.00318969,1.02842 kka2_1:2_M178A,kka2_1:2_178,Kka2,kka2_1:2,P00552,1.02842,NO,178,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-3.206,-2.643,-0.563,,0.554,.,b,0.55,0.68,3.152,,71.59,BHO,-2.154,0.295029,0.00717253,1.02842 beta-lactamase_156_P25N,beta-lactamase_156_25,TEM-1,beta-lactamase_156,P62593,1.02843,NO,25,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.526,-3.702,2.176,,0.624,H,A,0.52,0.14,1.079,,73.08,BOA,-2.15367,0.111618,0.00347571,1.02843 beta-lactamase_625_V106F,beta-lactamase_625_106,TEM-1,beta-lactamase_625,P62593,1.02844,NO,106,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.218,-2.585,1.367,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.213352,0.00304168,1.02844 beta-lactamase_625_E61M,beta-lactamase_625_61,TEM-1,beta-lactamase_625,P62593,1.02845,NO,61,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.115,-4.881,2.766,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.213352,0.00440955,1.02845 beta-lactamase_T193S,beta-lactamase_193,TEM-1,beta-lactamase,P62593,1.02845,NO,193,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.914,-2.571,0.657,5.67952,0.439,H,a,0.3,0.33,1.863,,63.99,HPO,-1.52133,0.221079,0.00482669,1.02845 Pab1_L190T,Pab1_190,Pab1,Pab1,P04147,1.02845,NO,190,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.325,-3.256,1.931,,0.489,E,B,,2.59,,,,HHH,-1.31033,0.175299,0.00132347,1.02845 PSD95pdz3_R313L,PSD95pdz3_313,PSD95pdz3,PSD95pdz3,P31016,1.02845,NO,313,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.582,-3.04,1.458,6.63563,,,,,18.3955,,,,BBH,-1.59733,0.0758425,0.000840067,1.02845 beta-lactamase_156_A84K,beta-lactamase_156_84,TEM-1,beta-lactamase_156,P62593,1.02847,NO,84,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.651,-2.484,0.833,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.111618,0.00503822,1.02847 beta-lactamase_0_H151Q,beta-lactamase_0_151,TEM-1,beta-lactamase_0,P62593,1.02848,NO,151,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-2.96,-2.497,-0.463,,0.594,H,A,0.17,0.1,9.375,,77.62,HBP,-2.34767,0.0500837,0.00216946,1.02848 beta-lactamase_39_I245T,beta-lactamase_39_245,TEM-1,beta-lactamase_39,P62593,1.02848,NO,245,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.0495842,0.00391032,1.02848 beta-lactamase_39_R92D,beta-lactamase_39_92,TEM-1,beta-lactamase_39,P62593,1.0285,NO,92,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.718,-3.708,1.99,,0.479,E,B,1.2,1.36,0.389,,65.38,BBH,-1.50367,0.0495842,0.00429626,1.0285 PSD95pdz3_G322N,PSD95pdz3_322,PSD95pdz3,PSD95pdz3,P31016,1.0285,NO,322,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.008,-3.13,2.122,5.24791,,,,,16.3275,,,,POH,-1.24867,0.0758425,0.00105821,1.0285 beta-lactamase_39_T27N,beta-lactamase_39_27,TEM-1,beta-lactamase_39,P62593,1.02852,NO,27,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.905,-2.525,0.62,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.0495842,0.00306559,1.02852 PSD95pdz3_G322C,PSD95pdz3_322,PSD95pdz3,PSD95pdz3,P31016,1.02852,NO,322,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.008,-4.769,3.761,5.24791,,,,,16.3275,,,,POH,-1.24867,0.0758425,0.00105821,1.02852 beta-lactamase_39_E108F,beta-lactamase_39_108,TEM-1,beta-lactamase_39,P62593,1.02853,NO,108,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.46,-4.416,2.956,,0.572,G,A,1.04,1.87,20.151,20.151,72.73,PAB,-1.437,0.0495842,0.00413372,1.02853 beta-lactamase_39_T27I,beta-lactamase_39_27,TEM-1,beta-lactamase_39,P62593,1.02853,NO,27,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.905,-3.752,1.847,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.0495842,0.00306559,1.02853 kka2_1:4_K112I,kka2_1:4_112,Kka2,kka2_1:4,P00552,1.02853,NO,112,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-2.491,-2.233,-0.258,,0.076,H,A,2.34,-1.37,0.39,,56.06,ABH,-2.00133,0.168804,0.00645389,1.02853 beta-lactamase_156_N50M,beta-lactamase_156_50,TEM-1,beta-lactamase_156,P62593,1.02855,NO,50,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-2.979,-4.727,1.748,,0.912,T,A,0.61,1.24,13.295,13.295,77.62,HPP,-2.134,0.111618,0.0047211,1.02855 beta-lactamase_156_T27N,beta-lactamase_156_27,TEM-1,beta-lactamase_156,P62593,1.02856,NO,27,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.905,-2.525,0.62,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.111618,0.00306559,1.02856 beta-lactamase_39_S241Q,beta-lactamase_39_241,TEM-1,beta-lactamase_39,P62593,1.02856,NO,241,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.0495842,0.00452736,1.02856 beta-lactamase_156_F149R,beta-lactamase_156_149,TEM-1,beta-lactamase_156,P62593,1.02858,NO,149,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.299,-4.139,2.84,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.111618,0.00418462,1.02858 beta-lactamase_625_A200N,beta-lactamase_625_200,TEM-1,beta-lactamase_625,P62593,1.0286,NO,200,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.878,-3.758,1.88,,0.757,H,A,0.46,-0.19,12.672,12.672,77.62,HHP,-2.001,0.213352,0.0060056,1.0286 PSD95pdz3_A370C,PSD95pdz3_370,PSD95pdz3,PSD95pdz3,P31016,1.02861,NO,370,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.307,-4.094,2.787,5.22304,,,,,17.284,,,,PHP,-1.57967,0.0758425,0.000429106,1.02861 beta-lactamase_0_E166R,beta-lactamase_0_166,TEM-1,beta-lactamase_0,P62593,1.02862,NO,166,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.756,-3.805,2.049,,0.508,G,A,1.04,1.05,17.227,17.227,73.08,OAH,-1.42233,0.0500837,0.00512989,1.02862 kka2_1:8_R239Y,kka2_1:8_239,Kka2,kka2_1:8,P00552,1.02862,NO,239,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.949,-4.327,1.378,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.100394,0.00835326,1.02862 kka2_1:8_R239Y,kka2_1:8_239,Kka2,kka2_1:8,P00552,1.02862,NO,239,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.949,-4.327,1.378,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.100394,0.00835326,1.02862 beta-lactamase_156_S80E,beta-lactamase_156_80,TEM-1,beta-lactamase_156,P62593,1.02863,NO,80,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.029,-2.666,0.637,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.111618,0.00565569,1.02863 beta-lactamase_39_E166H,beta-lactamase_39_166,TEM-1,beta-lactamase_39,P62593,1.02864,NO,166,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.756,-4.668,2.912,,0.508,G,A,1.04,1.05,17.227,17.227,73.08,OAH,-1.42233,0.0495842,0.00512989,1.02864 beta-lactamase_39_G141P,beta-lactamase_39_141,TEM-1,beta-lactamase_39,P62593,1.02865,NO,141,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.828,-3.881,3.053,,0.575,T,l,0.29,-0.28,0.722,,64.69,HOO,-1.08933,0.0495842,0.0012419,1.02865 beta-lactamase_39_S256F,beta-lactamase_39_256,TEM-1,beta-lactamase_39,P62593,1.02865,NO,256,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.0495842,0.00710634,1.02865 beta-lactamase_156_A215C,beta-lactamase_156_215,TEM-1,beta-lactamase_156,P62593,1.02866,NO,215,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.503,-4.816,3.313,,,,a,0.46,-0.93,3.583,,74.48,HHO,-1.42633,0.111618,0.00544007,1.02866 kka2_1:8_P12Y,kka2_1:8_12,Kka2,kka2_1:8,P00552,1.02866,NO,12,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.853,-4.385,3.532,,,.,B,0.52,1.25,2.41,,48.11,POH,-1.80767,0.100394,0.00500011,1.02866 kka2_1:8_P12Y,kka2_1:8_12,Kka2,kka2_1:8,P00552,1.02866,NO,12,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.853,-4.385,3.532,,,.,B,0.52,1.25,2.41,,48.11,POH,-1.80767,0.100394,0.00500011,1.02866 beta-lactamase_156_R118L,beta-lactamase_156_118,TEM-1,beta-lactamase_156,P62593,1.02867,NO,118,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.413,-2.872,0.459,,0.457,H,A,1.2,1.39,2.231,,77.62,HBA,-1.785,0.111618,0.00538794,1.02867 gb1_V255M,gb1_255,gb1,gb1,P06654,1.02867,NO,255,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-3.127,-4.414,1.287,,,,,,,1.323,,45.54,BHH,-2.03867,0.177985,0.00408354,1.02867 beta-lactamase_625_E210Q,beta-lactamase_625_210,TEM-1,beta-lactamase_625,P62593,1.02869,NO,210,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.319,-2.627,0.308,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.213352,0.00663582,1.02869 kka2_1:8_A14P,kka2_1:8_14,Kka2,kka2_1:8,P00552,1.02871,NO,14,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.837,-3.126,1.289,,0.728,G,A,0.46,0.7,,,71.59,HHH,-1.82567,0.100394,0.00706614,1.02871 kka2_1:8_A14P,kka2_1:8_14,Kka2,kka2_1:8,P00552,1.02871,NO,14,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.837,-3.126,1.289,,0.728,G,A,0.46,0.7,,,71.59,HHH,-1.82567,0.100394,0.00706614,1.02871 beta-lactamase_0_A246W,beta-lactamase_0_246,TEM-1,beta-lactamase_0,P62593,1.02872,NO,246,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.121,-5.267,3.146,,0.01,E,B,0.46,-1.01,1.201,,73.78,HHH,-1.55633,0.0500837,0.00569458,1.02872 beta-lactamase_0_T269Q,beta-lactamase_0_269,TEM-1,beta-lactamase_0,P62593,1.02872,NO,269,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.0500837,0.00950944,1.02872 beta-lactamase_156_I277F,beta-lactamase_156_277,TEM-1,beta-lactamase_156,P62593,1.02872,NO,277,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.111618,0.0169305,1.02872 beta-lactamase_156_V157Y,beta-lactamase_156_157,TEM-1,beta-lactamase_156,P62593,1.02872,NO,157,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.751,-2.838,1.087,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.111618,0.00506849,1.02872 beta-lactamase_39_R242C,beta-lactamase_39_242,TEM-1,beta-lactamase_39,P62593,1.02872,NO,242,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.0495842,0.00452879,1.02872 kka2_1:8_R89H,kka2_1:8_89,Kka2,kka2_1:8,P00552,1.02875,NO,89,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.548,-2.435,0.887,,0.209,E,B,1.2,1.41,25.3,25.3,64.39,OBA,-1.89867,0.100394,0.00524373,1.02875 kka2_1:8_R89H,kka2_1:8_89,Kka2,kka2_1:8,P00552,1.02875,NO,89,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.548,-2.435,0.887,,0.209,E,B,1.2,1.41,25.3,25.3,64.39,OBA,-1.89867,0.100394,0.00524373,1.02875 beta-lactamase_N173W,beta-lactamase_173,TEM-1,beta-lactamase,P62593,1.02879,NO,173,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-2.663,-5.303,2.64,7.02497,1.044,T,l,0.09,1.25,1.88,,77.62,OPA,-1.46633,0.221079,0.0033769,1.02879 beta-lactamase_0_H94A,beta-lactamase_0_94,TEM-1,beta-lactamase_0,P62593,1.0288,NO,94,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-2.5,-2.468,-0.032,,0.776,,B,0.17,1.24,1.176,,77.62,HBH,-1.872,0.0500837,0.00389226,1.0288 beta-lactamase_156_E87V,beta-lactamase_156_87,TEM-1,beta-lactamase_156,P62593,1.0288,NO,87,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.421,-2.385,0.964,,0.048,,B,1.04,0.92,1.754,,64.69,PAP,-1.969,0.111618,0.00337888,1.0288 gb1_T251P,gb1_251,gb1,gb1,P06654,1.0288,NO,251,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.794,-3.572,1.778,,,,,,,3.514,3.514,37.28,HPH,-1.56067,0.177985,0.00232932,1.0288 kka2_1:2_V49C,kka2_1:2_49,Kka2,kka2_1:2,P00552,1.0288,NO,49,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.614,-4.784,3.17,,,E,B,0.44,-0.77,1.233,,64.39,HHB,-1.3,0.295029,0.00615685,1.0288 kka2_1:4_M148Q,kka2_1:4_148,Kka2,kka2_1:4,P00552,1.02881,NO,148,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.847,-4.147,2.3,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.168804,0.00982664,1.02881 beta-lactamase_39_E87H,beta-lactamase_39_87,TEM-1,beta-lactamase_39,P62593,1.02883,NO,87,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.421,-4.575,3.154,,0.048,,B,1.04,0.92,15.231,15.231,64.69,PAP,-1.969,0.0495842,0.00337888,1.02883 PSD95pdz3_L323W,PSD95pdz3_323,PSD95pdz3,PSD95pdz3,P31016,1.02883,NO,323,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.347,-4.779,3.432,5.12397,,,,,13.8825,,,,OHO,-1.121,0.0758425,0.00104644,1.02883 beta-lactamase_156_T27K,beta-lactamase_156_27,TEM-1,beta-lactamase_156,P62593,1.02885,NO,27,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.905,-3.516,1.611,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.111618,0.00306559,1.02885 beta-lactamase_0_V101A,beta-lactamase_0_101,TEM-1,beta-lactamase_0,P62593,1.02886,NO,101,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.295,-3.114,1.819,,0.342,,B,0.44,0,1.61,,73.08,HHA,-1.54367,0.0500837,0.00374492,1.02886 beta-lactamase_0_M180A,beta-lactamase_0_180,TEM-1,beta-lactamase_0,P62593,1.02889,NO,180,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-2.795,-2.974,0.179,,0.242,,B,0.55,-0.94,2.892,,77.62,PHO,-1.56433,0.0500837,0.00552048,1.02889 beta-lactamase_R118Y,beta-lactamase_118,TEM-1,beta-lactamase,P62593,1.02889,NO,118,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.413,-4.398,1.985,5.8227,0.457,H,A,0.68,1.39,2.144,,77.62,HBA,-1.785,0.221079,0.00538794,1.02889 beta-lactamase_39_C75S,beta-lactamase_39_75,TEM-1,beta-lactamase_39,P62593,1.02891,NO,75,C,S,CS,Special,Polar,5.07,5.68,0.61,112,121,105,-16,108.5,89,-19.5,-1.245,-2.597,1.352,,,H,A,0.46,-0.87,2.369,,50,HOO,-1.24333,0.0495842,0.0034616,1.02891 beta-lactamase_39_I45F,beta-lactamase_39_45,TEM-1,beta-lactamase_39,P62593,1.02891,NO,45,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-2.421,-3.147,0.726,,,E,B,0.48,-0.3,2.256,,77.62,HHA,-2.30267,0.0495842,0.00452842,1.02891 PSD95pdz3_L353P,PSD95pdz3_353,PSD95pdz3,PSD95pdz3,P31016,1.02892,NO,353,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.347,-3.786,2.439,5.81136,,,,,17.3525,,,,AHB,-1.50533,0.0758425,0.000664742,1.02892 beta-lactamase_39_E87F,beta-lactamase_39_87,TEM-1,beta-lactamase_39,P62593,1.02894,NO,87,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.421,-4.277,2.856,,0.048,,B,1.04,0.92,15.231,15.231,64.69,PAP,-1.969,0.0495842,0.00337888,1.02894 kka2_1:1_Q61K,kka2_1:1_61,Kka2,kka2_1:1,P00552,1.02894,NO,61,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.982,-3.601,0.619,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.520039,0.00612092,1.02894 beta-lactamase_39_A124V,beta-lactamase_39_124,TEM-1,beta-lactamase_39,P62593,1.02896,NO,124,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.181,-2.519,1.338,,,H,A,0.46,-0.9,1.367,,64.34,HHH,-1.152,0.0495842,0.00481399,1.02896 beta-lactamase_39_N168M,beta-lactamase_39_168,TEM-1,beta-lactamase_39,P62593,1.02896,NO,168,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-1.029,-4.683,3.654,,0.113,G,A,0.61,-0.4,0.822,,44.41,HPA,-1.13233,0.0495842,0.00288667,1.02896 beta-lactamase_625_S283Y,beta-lactamase_625_283,TEM-1,beta-lactamase_625,P62593,1.02896,NO,283,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.213352,0.0429138,1.02896 kka2_1:4_C209L,kka2_1:4_209,Kka2,kka2_1:4,P00552,1.02896,NO,209,C,L,CL,Special,Hydrophobic,5.07,9.7088,4.6388,198,121,131,10,108.5,166.7,58.2,-0.906,-2.447,1.541,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.168804,0.00260862,1.02896 beta-lactamase_39_E26F,beta-lactamase_39_26,TEM-1,beta-lactamase_39,P62593,1.02899,NO,26,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.454,-4.297,1.843,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.0495842,0.00297948,1.02899 beta-lactamase_39_I93S,beta-lactamase_39_93,TEM-1,beta-lactamase_39,P62593,1.02899,NO,93,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.401,-3.663,2.262,,0.128,E,B,0.48,0.44,1.757,,67.83,BHB,-1.873,0.0495842,0.00527066,1.02899 beta-lactamase_39_T126S,beta-lactamase_39_126,TEM-1,beta-lactamase_39,P62593,1.02899,NO,126,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.122,-2.464,1.342,,0.05,H,A,0.22,-0.05,0.586,,44.41,HPH,-1.60467,0.0495842,0.00244552,1.02899 beta-lactamase_39_T131F,beta-lactamase_39_131,TEM-1,beta-lactamase_39,P62593,1.02899,NO,131,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.328,-4.204,2.876,,,H,A,0.22,-0.69,3.306,,67.48,PPH,-1.00867,0.0495842,0.00345886,1.02899 beta-lactamase_39_T186N,beta-lactamase_39_186,TEM-1,beta-lactamase_39,P62593,1.02901,NO,186,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.522,-3.756,1.234,,0.396,H,A,0.22,-0.28,0.515,,77.62,HPP,-1.77633,0.0495842,0.00485034,1.02901 PSD95pdz3_H317T,PSD95pdz3_317,PSD95pdz3,PSD95pdz3,P31016,1.02901,NO,317,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-1.627,-3.328,1.701,6.19713,,,,,25.885,,,,HBB,-1.613,0.0758425,0.00111619,1.02901 beta-lactamase_Q265K,beta-lactamase_265,TEM-1,beta-lactamase,P62593,1.02902,NO,265,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.58,-2.94,0.36,6.62674,1.116,,A,0.03,1.17,12.514,12.514,69.58,PPH,-1.978,0.221079,0.00811926,1.02902 beta-lactamase_T186F,beta-lactamase_186,TEM-1,beta-lactamase,P62593,1.02902,NO,186,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.522,-4.342,1.82,5.07364,0.396,H,A,0.3,-0.28,2.144,,77.62,HPP,-1.77633,0.221079,0.00485034,1.02902 PSD95pdz3_G351K,PSD95pdz3_351,PSD95pdz3,PSD95pdz3,P31016,1.02902,NO,351,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.008,-3.364,2.356,5.44798,,,,,20.7625,,,,POA,-1.37133,0.0758425,0.000691282,1.02902 beta-lactamase_39_L79N,beta-lactamase_39_79,TEM-1,beta-lactamase_39,P62593,1.02903,NO,79,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.842,-4.12,3.278,,0.007,H,A,0.55,-0.16,0.823,,50.35,HHP,-1.44333,0.0495842,0.000947397,1.02903 beta-lactamase_625_A211V,beta-lactamase_625_211,TEM-1,beta-lactamase_625,P62593,1.02903,NO,211,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.896,-3.651,1.755,,0.369,T,A,0.46,-0.69,2.061,,77.62,AHA,-1.94633,0.213352,0.00648183,1.02903 beta-lactamase_156_A170M,beta-lactamase_156_170,TEM-1,beta-lactamase_156,P62593,1.02905,NO,170,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.237,-4.595,3.358,,0.126,,L,0.46,-0.35,3.7,,64.69,AHH,-1.63267,0.111618,0.00431903,1.02905 beta-lactamase_2500_T193K,beta-lactamase_2500_193,TEM-1,beta-lactamase_2500,P62593,1.02907,NO,193,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.914,-3.726,1.812,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.361275,0.00482669,1.02907 beta-lactamase_39_R63C,beta-lactamase_39_63,TEM-1,beta-lactamase_39,P62593,1.02908,NO,63,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-0.943,-5.05,4.107,,0.218,,B,1.2,-0.31,0.326,,44.06,ABH,-0.992333,0.0495842,0.00126938,1.02908 beta-lactamase_T138K,beta-lactamase_138,TEM-1,beta-lactamase,P62593,1.02913,NO,138,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.506,-2.186,-0.32,5.52585,0.662,H,A,0.3,-0.03,30.445,30.445,73.78,HPP,-1.81233,0.221079,0.00487868,1.02913 beta-lactamase_0_A225P,beta-lactamase_0_225,TEM-1,beta-lactamase_0,P62593,1.02915,NO,225,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.845,-3.112,1.267,,1,T,B,0.46,-0.38,11.722,11.722,74.48,OHO,-1.39967,0.0500837,0.00465057,1.02915 beta-lactamase_0_L223V,beta-lactamase_0_223,TEM-1,beta-lactamase_0,P62593,1.02916,NO,223,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.055,-2.195,1.14,,0.27,,B,0.55,0.09,1.633,,74.48,HHO,-1.35033,0.0500837,0.00372793,1.02916 beta-lactamase_156_E108P,beta-lactamase_156_108,TEM-1,beta-lactamase_156,P62593,1.02916,NO,108,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.46,-3.855,2.395,,0.572,G,A,1.04,1.87,8.602,8.602,72.73,PAB,-1.437,0.111618,0.00413372,1.02916 beta-lactamase_39_A278K,beta-lactamase_39_278,TEM-1,beta-lactamase_39,P62593,1.02916,NO,278,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.0495842,0.0310297,1.02916 beta-lactamase_39_E279I,beta-lactamase_39_279,TEM-1,beta-lactamase_39,P62593,1.02916,NO,279,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.0495842,0.0192826,1.02916 E1_Ubiquitin_A46M,E1_Ubiquitin_46,Uba1,E1_Ubiquitin,P0CG63,1.02918,NO,46,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.367,-4.335,2.968,,0.398,T,L,,-0.8,,,,HHO,-1.17167,0.18783,0.004233,1.02918 E1_Ubiquitin_K48A,E1_Ubiquitin_48,Uba1,E1_Ubiquitin,P0CG63,1.02918,NO,48,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.219,-2.948,1.729,,0.132,E,B,,-0.28,,,,OBO,-1.109,0.18783,0.00100363,1.02918 E1_Ubiquitin_K48N,E1_Ubiquitin_48,Uba1,E1_Ubiquitin,P0CG63,1.02918,NO,48,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.219,-3.318,2.099,,0.132,E,B,,-0.28,,,,OBO,-1.109,0.18783,0.00100363,1.02918 E1_Ubiquitin_Q41N,E1_Ubiquitin_41,Uba1,E1_Ubiquitin,P0CG63,1.02918,NO,41,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-1.25,-3.265,2.015,,0.017,E,B,,-0.98,,,,PPB,-1.344,0.18783,0.00215097,1.02918 beta-lactamase_A182I,beta-lactamase_182,TEM-1,beta-lactamase,P62593,1.0292,NO,182,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.777,-3.851,2.074,4.98609,0.136,H,A,0.52,-0.66,2.032,,93.01,OHH,-1.27367,0.221079,0.00559099,1.0292 beta-lactamase_R41K,beta-lactamase_41,TEM-1,beta-lactamase,P62593,1.0292,NO,41,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-0.942,-2.85,1.908,5.69185,0.321,E,B,0.91,-0.07,4.357,,65.03,HBH,-1.30267,0.221079,0.00123327,1.0292 beta-lactamase_156_R41I,beta-lactamase_156_41,TEM-1,beta-lactamase_156,P62593,1.02921,NO,41,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-0.942,-4.008,3.066,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.111618,0.00123327,1.02921 PSD95pdz3_T385L,PSD95pdz3_385,PSD95pdz3,PSD95pdz3,P31016,1.02921,NO,385,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.533,-2.994,1.461,5.57157,,,,,23.6871,4.527,,87.71,PPH,-1.56567,0.0758425,0.000545119,1.02921 beta-lactamase_39_A200N,beta-lactamase_39_200,TEM-1,beta-lactamase_39,P62593,1.02924,NO,200,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.878,-3.758,1.88,,0.757,H,A,0.46,-0.19,1.54,,77.62,HHP,-2.001,0.0495842,0.0060056,1.02924 beta-lactamase_K284E,beta-lactamase_284,TEM-1,beta-lactamase,P62593,1.02924,NO,284,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.981,-1.835,-0.146,6.30084,0.848,H,A,1.82,0.67,1.931,,77.62,HBB,-1.82133,0.221079,0.0686156,1.02924 beta-lactamase_0_K30D,beta-lactamase_0_30,TEM-1,beta-lactamase_0,P62593,1.02932,NO,30,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-2.307,-3.567,1.26,,0.142,H,A,2.34,-0.65,1.491,,93.01,HBH,-2.32833,0.0500837,0.00448593,1.02932 beta-lactamase_39_K109W,beta-lactamase_39_109,TEM-1,beta-lactamase_39,P62593,1.02935,NO,109,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.734,-5.518,3.784,,0.787,G,A,2.34,2.21,7.243,,72.73,ABB,-1.63333,0.0495842,0.00462493,1.02935 beta-lactamase_625_R176C,beta-lactamase_625_176,TEM-1,beta-lactamase_625,P62593,1.02935,NO,176,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-0.863,-5.087,4.224,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.213352,0.00105554,1.02935 beta-lactamase_2500_K190L,beta-lactamase_2500_190,TEM-1,beta-lactamase_2500,P62593,1.02937,NO,190,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.994,-3.527,1.533,,0.371,H,A,2.34,0.16,29.753,29.753,77.62,BBH,-1.64167,0.361275,0.00574527,1.02937 PSD95pdz3_N326I,PSD95pdz3_326,PSD95pdz3,PSD95pdz3,P31016,1.02937,NO,326,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-1.41,-3.692,2.282,5.52537,,,,,19.0688,,,,HPH,-1.52133,0.0758425,0.00101078,1.02937 beta-lactamase_39_A222Q,beta-lactamase_39_222,TEM-1,beta-lactamase_39,P62593,1.02938,NO,222,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.103,-4.105,2.002,,0.233,H,A,0.46,-0.25,1.448,,77.62,PHH,-1.63733,0.0495842,0.00466094,1.02938 beta-lactamase_39_F58Q,beta-lactamase_39_58,TEM-1,beta-lactamase_39,P62593,1.02938,NO,58,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-2.914,-2.803,-0.111,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.0495842,0.00523369,1.02938 kka2_1:2_K138M,kka2_1:2_138,Kka2,kka2_1:2,P00552,1.02938,NO,138,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-2.5,-4.844,2.344,,0.594,H,A,2.34,0.98,21.038,21.038,71.59,HBB,-2.48833,0.295029,0.00628542,1.02938 beta-lactamase_39_K213F,beta-lactamase_39_213,TEM-1,beta-lactamase_39,P62593,1.02943,NO,213,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.81,-4.437,2.627,,0.67,,A,2.34,0.29,2.648,,67.83,ABH,-1.57767,0.0495842,0.00610411,1.02943 beta-lactamase_E102Q,beta-lactamase_102,TEM-1,beta-lactamase,P62593,1.02944,NO,102,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.118,-3.043,0.925,6.36157,0.722,S,B,1.5,1.82,1.336,,73.08,HAH,-1.581,0.221079,0.00486633,1.02944 beta-lactamase_39_V29T,beta-lactamase_39_29,TEM-1,beta-lactamase_39,P62593,1.02946,NO,29,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-2.856,-2.552,-0.304,,0.733,H,A,0.44,-0.78,1.287,,93.01,HHB,-2.24733,0.0495842,0.00318969,1.02946 PSD95pdz3_L349E,PSD95pdz3_349,PSD95pdz3,PSD95pdz3,P31016,1.02946,NO,349,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.347,-3.572,2.225,5.14696,,,,,24.6438,,,,AHP,-1.37667,0.0758425,0.00071841,1.02946 beta-lactamase_156_T112E,beta-lactamase_156_112,TEM-1,beta-lactamase_156,P62593,1.02948,NO,112,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.186,-2.494,0.308,,0.921,T,A,0.22,1.06,2.87,,73.78,HPA,-1.925,0.111618,0.00531334,1.02948 PSD95pdz3_N326K,PSD95pdz3_326,PSD95pdz3,PSD95pdz3,P31016,1.02949,NO,326,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-1.41,-2.914,1.504,5.52537,,,,,19.0688,,,,HPH,-1.52133,0.0758425,0.00101078,1.02949 PSD95pdz3_A343V,PSD95pdz3_343,PSD95pdz3,PSD95pdz3,P31016,1.0295,NO,343,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.307,-2.76,1.453,5.585,,,,,14.728,,,,HHO,-1.22067,0.0758425,0.000798084,1.0295 beta-lactamase_39_E166A,beta-lactamase_39_166,TEM-1,beta-lactamase_39,P62593,1.02952,NO,166,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.756,-2.056,0.3,,0.508,G,A,1.04,1.05,17.227,17.227,73.08,OAH,-1.42233,0.0495842,0.00512989,1.02952 beta-lactamase_39_K109Y,beta-lactamase_39_109,TEM-1,beta-lactamase_39,P62593,1.02952,NO,109,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.734,-4.334,2.6,,0.787,G,A,2.34,2.21,7.243,,72.73,ABB,-1.63333,0.0495842,0.00462493,1.02952 beta-lactamase_D207A,beta-lactamase_207,TEM-1,beta-lactamase,P62593,1.02953,NO,207,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.064,-2.585,0.521,5.40404,0.409,H,A,0.23,0.12,1.975,,77.62,HAH,-1.77033,0.221079,0.00592942,1.02953 beta-lactamase_P60G,beta-lactamase_60,TEM-1,beta-lactamase,P62593,1.02956,NO,60,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-2.469,-2.095,-0.374,5.51353,0.256,T,A,0.73,-0.56,3.653,,77.62,BOA,-1.97633,0.221079,0.00521318,1.02956 kka2_1:2_A108C,kka2_1:2_108,Kka2,kka2_1:2,P00552,1.02956,NO,108,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.061,-5.089,3.028,,0.243,.,B,0.46,-1.34,2.462,,71.59,HHO,-1.57033,0.295029,0.00751209,1.02956 beta-lactamase_0_G114T,beta-lactamase_0_114,TEM-1,beta-lactamase_0,P62593,1.02957,NO,114,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.094,-2.276,1.182,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.0500837,0.00224919,1.02957 beta-lactamase_156_P25W,beta-lactamase_156_25,TEM-1,beta-lactamase_156,P62593,1.02959,NO,25,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.526,-5.419,3.893,,0.624,H,A,0.52,0.14,1.079,,73.08,BOA,-2.15367,0.111618,0.00347571,1.02959 beta-lactamase_39_T263M,beta-lactamase_39_263,TEM-1,beta-lactamase_39,P62593,1.02959,NO,263,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.0495842,0.0110582,1.02959 beta-lactamase_156_I244L,beta-lactamase_156_244,TEM-1,beta-lactamase_156,P62593,1.0296,NO,244,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.555,-2.697,1.142,,,E,B,0.48,-0.84,1.325,,77.62,OHH,-1.385,0.111618,0.00605379,1.0296 beta-lactamase_156_L284I,beta-lactamase_156_284,TEM-1,beta-lactamase_156,P62593,1.0296,NO,284,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.111618,0.0686156,1.0296 PSD95pdz3_R354H,PSD95pdz3_354,PSD95pdz3,PSD95pdz3,P31016,1.0296,NO,354,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.582,-3.912,2.33,6.21887,,,,,23.7791,,,,HBB,-1.44833,0.0758425,0.000650924,1.0296 beta-lactamase_0_I285G,beta-lactamase_0_285,TEM-1,beta-lactamase_0,P62593,1.02961,NO,285,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.0500837,0.101555,1.02961 beta-lactamase_39_E166D,beta-lactamase_39_166,TEM-1,beta-lactamase_39,P62593,1.02961,NO,166,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.756,-2.259,0.503,,0.508,G,A,1.04,1.05,17.227,17.227,73.08,OAH,-1.42233,0.0495842,0.00512989,1.02961 gb1_T244R,gb1_244,gb1,gb1,P06654,1.02961,NO,244,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.637,-3.719,2.082,,,,,,,0.202,,11.83,PPA,-1.92567,0.177985,0.00222755,1.02961 beta-lactamase_156_E166I,beta-lactamase_156_166,TEM-1,beta-lactamase_156,P62593,1.02963,NO,166,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.756,-3.874,2.118,,0.508,G,A,1.04,1.05,2.393,,73.08,OAH,-1.42233,0.111618,0.00512989,1.02963 beta-lactamase_39_L38E,beta-lactamase_39_38,TEM-1,beta-lactamase_39,P62593,1.02965,NO,38,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.343,-3.797,2.454,,0.088,H,A,0.55,0.2,17.089,17.089,64.34,PHO,-1.78033,0.0495842,0.00373244,1.02965 PSD95pdz3_S320Y,PSD95pdz3_320,PSD95pdz3,PSD95pdz3,P31016,1.02965,NO,320,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.519,-3.844,2.325,5.81757,,,,,21.4517,,,,OPP,-1.306,0.0758425,0.00108158,1.02965 beta-lactamase_G194T,beta-lactamase_194,TEM-1,beta-lactamase,P62593,1.02966,NO,194,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.396,-2.79,1.394,5.46622,0.276,S,b,0.77,0.36,3.593,,67.83,POA,-1.832,0.221079,0.00392163,1.02966 beta-lactamase_I54V,beta-lactamase_54,TEM-1,beta-lactamase,P62593,1.02966,NO,54,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-2.838,-2.687,-0.151,5.40541,0.669,E,B,0.77,-0.14,3.946,,73.78,BHH,-2.337,0.221079,0.00403589,1.02966 kka2_1:8_T85I,kka2_1:8_85,Kka2,kka2_1:8,P00552,1.02968,NO,85,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.165,-2.979,0.814,,0.576,E,B,0.22,1.39,22.154,22.154,71.59,HPA,-2.10133,0.100394,0.00634493,1.02968 kka2_1:8_T85I,kka2_1:8_85,Kka2,kka2_1:8,P00552,1.02968,NO,85,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.165,-2.979,0.814,,0.576,E,B,0.22,1.39,22.154,22.154,71.59,HPA,-2.10133,0.100394,0.00634493,1.02968 beta-lactamase_156_A211E,beta-lactamase_156_211,TEM-1,beta-lactamase_156,P62593,1.02969,NO,211,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.896,-2.447,0.551,,0.369,T,A,0.46,-0.69,8.527,8.527,77.62,AHA,-1.94633,0.111618,0.00648183,1.02969 beta-lactamase_L205L,beta-lactamase_205,TEM-1,beta-lactamase,P62593,1.02969,NO,205,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.922,-0.922,,5.67023,,H,A,1.3,-0.46,0.678,,42.31,PHH,-1.57767,0.221079,0.00255802,1.02969 kka2_1:8_P128W,kka2_1:8_128,Kka2,kka2_1:8,P00552,1.02971,NO,128,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.922,-3.525,1.603,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.100394,0.00774689,1.02971 kka2_1:8_P128W,kka2_1:8_128,Kka2,kka2_1:8,P00552,1.02971,NO,128,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.922,-3.525,1.603,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.100394,0.00774689,1.02971 beta-lactamase_39_T126C,beta-lactamase_39_126,TEM-1,beta-lactamase_39,P62593,1.02974,NO,126,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.122,-4.816,3.694,,0.05,H,A,0.22,-0.05,0.586,,44.41,HPH,-1.60467,0.0495842,0.00244552,1.02974 beta-lactamase_39_S51D,beta-lactamase_39_51,TEM-1,beta-lactamase_39,P62593,1.02976,NO,51,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.526,-2.756,1.23,,0.496,T,A,0.27,0.26,2.964,,72.73,PPO,-1.88467,0.0495842,0.00504821,1.02976 beta-lactamase_625_T112E,beta-lactamase_625_112,TEM-1,beta-lactamase_625,P62593,1.02976,NO,112,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.186,-2.494,0.308,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.213352,0.00531334,1.02976 beta-lactamase_156_T138L,beta-lactamase_156_138,TEM-1,beta-lactamase_156,P62593,1.02979,NO,138,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.506,-3.638,1.132,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.111618,0.00487868,1.02979 beta-lactamase_0_A148N,beta-lactamase_0_148,TEM-1,beta-lactamase_0,P62593,1.0298,NO,148,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.757,-3.701,1.944,,0.379,H,A,0.46,-0.55,19.42,19.42,72.73,PHH,-1.40167,0.0500837,0.00547053,1.0298 beta-lactamase_39_E46W,beta-lactamase_39_46,TEM-1,beta-lactamase_39,P62593,1.0298,NO,46,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.94,-5.418,3.478,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.0495842,0.00427568,1.0298 beta-lactamase_F58Y,beta-lactamase_58,TEM-1,beta-lactamase,P62593,1.0298,NO,58,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-2.914,-1.89,-1.024,5.55634,0.266,E,B,1.33,-0.07,2.467,,77.62,PHB,-2.059,0.221079,0.00523369,1.0298 beta-lactamase_39_L150G,beta-lactamase_39_150,TEM-1,beta-lactamase_39,P62593,1.02981,NO,150,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.326,-3.622,2.296,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.0495842,0.00463171,1.02981 beta-lactamase_156_I285M,beta-lactamase_156_285,TEM-1,beta-lactamase_156,P62593,1.02982,NO,285,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.111618,0.101555,1.02982 PSD95pdz3_G335Y,PSD95pdz3_335,PSD95pdz3,PSD95pdz3,P31016,1.02982,NO,335,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.008,-4.069,3.061,4.76223,,,,,22.4225,,,,AOH,-1.34733,0.0758425,0.000900493,1.02982 beta-lactamase_0_E102I,beta-lactamase_0_102,TEM-1,beta-lactamase_0,P62593,1.02986,NO,102,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.118,-4.045,1.927,,0.722,S,B,1.04,1.82,4.773,,73.08,HAH,-1.581,0.0500837,0.00486633,1.02986 beta-lactamase_39_C75A,beta-lactamase_39_75,TEM-1,beta-lactamase_39,P62593,1.02986,NO,75,C,A,CA,Special,Hydrophobic,5.07,6,0.93,195,121,89,-32,108.5,88.6,-19.9,-1.245,-1.87,0.625,,,H,A,0.46,-0.87,2.369,,50,HOO,-1.24333,0.0495842,0.0034616,1.02986 beta-lactamase_2500_S80E,beta-lactamase_2500_80,TEM-1,beta-lactamase_2500,P62593,1.02987,NO,80,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.029,-2.666,0.637,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.361275,0.00565569,1.02987 gb1_A274C,gb1_274,gb1,gb1,P06654,1.02987,NO,274,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.728,-4.701,2.973,,,,,,,4.162,4.162,11.83,AHP,-1.81767,0.177985,0.0068419,1.02987 gb1_D272I,gb1_272,gb1,gb1,P06654,1.02987,NO,272,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.457,-3.876,2.419,,,,,,,0.234,,11.83,HAA,-1.54533,0.177985,0.00218257,1.02987 beta-lactamase_2500_K190D,beta-lactamase_2500_190,TEM-1,beta-lactamase_2500,P62593,1.02988,NO,190,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.994,-3.691,1.697,,0.371,H,A,2.34,0.16,29.753,29.753,77.62,BBH,-1.64167,0.361275,0.00574527,1.02988 beta-lactamase_39_V82E,beta-lactamase_39_82,TEM-1,beta-lactamase_39,P62593,1.02988,NO,82,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.325,-3.751,2.426,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.0495842,0.00397046,1.02988 kka2_1:4_A41E,kka2_1:4_41,Kka2,kka2_1:4,P00552,1.02988,NO,41,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.879,-3.093,1.214,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.168804,0.00543332,1.02988 beta-lactamase_156_D33Q,beta-lactamase_156_33,TEM-1,beta-lactamase_156,P62593,1.02993,NO,33,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.321,-2.638,0.317,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.111618,0.00435556,1.02993 beta-lactamase_0_Y44D,beta-lactamase_0_44,TEM-1,beta-lactamase_0,P62593,1.02994,NO,44,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-2.547,-4.061,1.514,,,E,B,0.21,-0.45,1.751,,73.78,OHH,-1.86267,0.0500837,0.00426364,1.02994 beta-lactamase_39_D174Q,beta-lactamase_39_174,TEM-1,beta-lactamase_39,P62593,1.02994,NO,174,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.738,-3.674,2.936,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.0495842,0.00125633,1.02994 beta-lactamase_39_I93M,beta-lactamase_39_93,TEM-1,beta-lactamase_39,P62593,1.02994,NO,93,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.401,-4.189,2.788,,0.128,E,B,0.48,0.44,1.757,,67.83,BHB,-1.873,0.0495842,0.00527066,1.02994 beta-lactamase_0_A84Y,beta-lactamase_0_84,TEM-1,beta-lactamase_0,P62593,1.02995,NO,84,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.651,-4.29,2.639,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.0500837,0.00503822,1.02995 beta-lactamase_2500_K190S,beta-lactamase_2500_190,TEM-1,beta-lactamase_2500,P62593,1.03,NO,190,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.994,-2.653,0.659,,0.371,H,A,2.34,0.16,29.753,29.753,77.62,BBH,-1.64167,0.361275,0.00574527,1.03 beta-lactamase_156_M270D,beta-lactamase_156_270,TEM-1,beta-lactamase_156,P62593,1.03001,NO,270,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.111618,0.00767762,1.03001 beta-lactamase_39_G236E,beta-lactamase_39_236,TEM-1,beta-lactamase_39,P62593,1.03003,NO,236,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.784,-3.634,2.85,,0.241,,b,0.29,-0.59,1.883,,64.69,HOO,-1.025,0.0495842,0.00162372,1.03003 beta-lactamase_156_I277V,beta-lactamase_156_277,TEM-1,beta-lactamase_156,P62593,1.03004,NO,277,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.111618,0.0169305,1.03004 beta-lactamase_625_R118C,beta-lactamase_625_118,TEM-1,beta-lactamase_625,P62593,1.03004,NO,118,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.413,-4.992,2.579,,0.457,H,A,1.2,1.39,2.144,,77.62,HBA,-1.785,0.213352,0.00538794,1.03004 kka2_1:2_Q61P,kka2_1:2_61,Kka2,kka2_1:2,P00552,1.03005,NO,61,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.982,-1.818,-1.164,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.295029,0.00612092,1.03005 PSD95pdz3_I377E,PSD95pdz3_377,PSD95pdz3,PSD95pdz3,P31016,1.03005,NO,377,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.873,-3.611,1.738,4.9532,,,,,19.185,2.364,,87.71,HHH,-1.49567,0.0758425,0.000795475,1.03005 beta-lactamase_625_F70G,beta-lactamase_625_70,TEM-1,beta-lactamase_625,P62593,1.03006,NO,70,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.169,-3.574,2.405,,,H,A,0.58,-1.34,1.14,,63.99,PHB,-0.980667,0.213352,0.00193499,1.03006 kka2_1:8_G164K,kka2_1:8_164,Kka2,kka2_1:8,P00552,1.03006,NO,164,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.869,-3.652,2.783,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.100394,0.00442091,1.03006 kka2_1:8_G164K,kka2_1:8_164,Kka2,kka2_1:8,P00552,1.03006,NO,164,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.869,-3.652,2.783,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.100394,0.00442091,1.03006 beta-lactamase_39_S221Y,beta-lactamase_39_221,TEM-1,beta-lactamase_39,P62593,1.0301,NO,221,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.754,-4.278,2.524,,0.624,H,A,0.27,-0.2,2.69,,74.48,BPH,-1.59967,0.0495842,0.0046094,1.0301 beta-lactamase_156_R92C,beta-lactamase_156_92,TEM-1,beta-lactamase_156,P62593,1.03011,NO,92,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.718,-5.119,3.401,,0.479,E,B,1.2,1.36,19.112,19.112,65.38,BBH,-1.50367,0.111618,0.00429626,1.03011 beta-lactamase_156_T131S,beta-lactamase_156_131,TEM-1,beta-lactamase_156,P62593,1.03012,NO,131,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.328,-1.912,0.584,,,H,A,0.22,-0.69,2.031,,67.48,PPH,-1.00867,0.111618,0.00345886,1.03012 beta-lactamase_39_T27V,beta-lactamase_39_27,TEM-1,beta-lactamase_39,P62593,1.03012,NO,27,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.905,-3.409,1.504,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.0495842,0.00306559,1.03012 beta-lactamase_156_E87T,beta-lactamase_156_87,TEM-1,beta-lactamase_156,P62593,1.03013,NO,87,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.421,-2.787,1.366,,0.048,,B,1.04,0.92,1.754,,64.69,PAP,-1.969,0.111618,0.00337888,1.03013 beta-lactamase_39_R220P,beta-lactamase_39_220,TEM-1,beta-lactamase_39,P62593,1.03014,NO,220,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-0.942,-3.877,2.935,,0.295,I,A,1.2,-0.76,1.596,,74.48,HBP,-1.33633,0.0495842,0.00232421,1.03014 beta-lactamase_625_A278K,beta-lactamase_625_278,TEM-1,beta-lactamase_625,P62593,1.03014,NO,278,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.348,,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.213352,0.0310297,1.03014 beta-lactamase_0_G43F,beta-lactamase_0_43,TEM-1,beta-lactamase_0,P62593,1.03015,NO,43,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.62,-4.292,3.672,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.0500837,0.00120151,1.03015 beta-lactamase_39_H110W,beta-lactamase_39_110,TEM-1,beta-lactamase_39,P62593,1.03015,NO,110,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-1.706,-5.185,3.479,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.0495842,0.00441499,1.03015 beta-lactamase_L199P,beta-lactamase_199,TEM-1,beta-lactamase,P62593,1.03015,NO,199,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-2.942,-2.099,-0.843,5.57712,0.832,H,A,0.82,0.42,15.302,15.302,77.62,PHH,-2.32933,0.221079,0.0048649,1.03015 beta-lactamase_39_R202E,beta-lactamase_39_202,TEM-1,beta-lactamase_39,P62593,1.03016,NO,202,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.292,-3.173,1.881,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.0495842,0.00321899,1.03016 PSD95pdz3_Q391E,PSD95pdz3_391,PSD95pdz3,PSD95pdz3,P31016,1.03016,NO,391,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-1.699,-2.447,0.748,5.50275,,,,,12.6589,,,,HPH,-1.481,0.0758425,0.000990786,1.03016 beta-lactamase_I171A,beta-lactamase_171,TEM-1,beta-lactamase,P62593,1.0302,NO,171,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-2.431,-2.242,-0.189,5.22771,0.361,,B,1,0.53,1.66,,77.62,HHO,-1.55533,0.221079,0.00623355,1.0302 kka2_1:4_W24A,kka2_1:4_24,Kka2,kka2_1:4,P00552,1.0302,NO,24,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-1.779,-3.385,1.606,,0.477,E,B,1.51,-0.21,2.666,,56.06,AHH,-2.24467,0.168804,0.00631564,1.0302 beta-lactamase_625_V106S,beta-lactamase_625_106,TEM-1,beta-lactamase_625,P62593,1.03021,NO,106,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.218,-3.705,2.487,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.213352,0.00304168,1.03021 beta-lactamase_I54P,beta-lactamase_54,TEM-1,beta-lactamase,P62593,1.03022,NO,54,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-2.838,-4.045,1.207,5.40541,0.669,E,B,0.77,-0.14,3.946,,73.78,BHH,-2.337,0.221079,0.00403589,1.03022 beta-lactamase_156_I93K,beta-lactamase_156_93,TEM-1,beta-lactamase_156,P62593,1.03023,NO,93,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.401,-3.873,2.472,,0.128,E,B,0.48,0.44,1.524,,67.83,BHB,-1.873,0.111618,0.00527066,1.03023 beta-lactamase_39_L38C,beta-lactamase_39_38,TEM-1,beta-lactamase_39,P62593,1.03023,NO,38,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.343,-4.841,3.498,,0.088,H,A,0.55,0.2,17.089,17.089,64.34,PHO,-1.78033,0.0495842,0.00373244,1.03023 kka2_1:8_P98D,kka2_1:8_98,Kka2,kka2_1:8,P00552,1.03023,NO,98,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.526,-2.576,1.05,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.100394,0.00622754,1.03023 kka2_1:8_P98D,kka2_1:8_98,Kka2,kka2_1:8,P00552,1.03023,NO,98,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.526,-2.576,1.05,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.100394,0.00622754,1.03023 beta-lactamase_39_G141A,beta-lactamase_39_141,TEM-1,beta-lactamase_39,P62593,1.03024,NO,141,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.828,-2.988,2.16,,0.575,T,l,0.29,-0.28,0.722,,64.69,HOO,-1.08933,0.0495842,0.0012419,1.03024 beta-lactamase_625_K190Y,beta-lactamase_625_190,TEM-1,beta-lactamase_625,P62593,1.03025,NO,190,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.994,-4.283,2.289,,0.371,H,A,2.34,0.16,29.753,29.753,77.62,BBH,-1.64167,0.213352,0.00574527,1.03025 beta-lactamase_39_L55F,beta-lactamase_39_55,TEM-1,beta-lactamase_39,P62593,1.03027,NO,55,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.86,-2.527,0.667,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.0495842,0.00403741,1.03027 gb1_T275F,gb1_275,gb1,gb1,P06654,1.03027,NO,275,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.727,-3.93,2.203,,,,,,,0.511,,35.71,HPB,-1.637,0.177985,0.00606618,1.03027 beta-lactamase_156_P224K,beta-lactamase_156_224,TEM-1,beta-lactamase_156,P62593,1.03029,NO,224,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.893,-3.389,2.496,,0.383,,B,0.52,-0.3,0.383,,74.48,HOH,-1.26433,0.111618,0.00189564,1.03029 beta-lactamase_39_R91D,beta-lactamase_39_91,TEM-1,beta-lactamase_39,P62593,1.03029,NO,91,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.392,-3.521,2.129,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.0495842,0.00380226,1.03029 PSD95pdz3_D332L,PSD95pdz3_332,PSD95pdz3,PSD95pdz3,P31016,1.0303,NO,332,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.264,-3.49,2.226,6.09878,,,,,48.762,,,,AAO,-1.22533,0.0758425,0.000937818,1.0303 kka2_1:4_D33L,kka2_1:4_33,Kka2,kka2_1:4,P00552,1.03032,NO,33,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.186,-3.734,1.548,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.168804,0.00633568,1.03032 beta-lactamase_0_L100A,beta-lactamase_0_100,TEM-1,beta-lactamase_0,P62593,1.03033,NO,100,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.218,-3.158,1.94,,0.343,,B,0.55,0.13,1.373,,63.29,AHH,-1.23467,0.0500837,0.00413885,1.03033 beta-lactamase_39_E87P,beta-lactamase_39_87,TEM-1,beta-lactamase_39,P62593,1.03033,NO,87,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.421,-3.872,2.451,,0.048,,B,1.04,0.92,15.231,15.231,64.69,PAP,-1.969,0.0495842,0.00337888,1.03033 beta-lactamase_39_V29M,beta-lactamase_39_29,TEM-1,beta-lactamase_39,P62593,1.03034,NO,29,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-2.856,-4.721,1.865,,0.733,H,A,0.44,-0.78,1.287,,93.01,HHB,-2.24733,0.0495842,0.00318969,1.03034 beta-lactamase_39_T27H,beta-lactamase_39_27,TEM-1,beta-lactamase_39,P62593,1.03035,NO,27,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.905,-4.62,2.715,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.0495842,0.00306559,1.03035 beta-lactamase_625_S122D,beta-lactamase_625_122,TEM-1,beta-lactamase_625,P62593,1.03035,NO,122,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.406,-2.549,0.143,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.213352,0.00497825,1.03035 beta-lactamase_A15F,beta-lactamase_15,TEM-1,beta-lactamase,P62593,1.03038,NO,15,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.654,-4.064,2.41,,,,,,,31.998,31.998,93.01,HHH,-2.10833,0.221079,0.00248966,1.03038 beta-lactamase_S122L,beta-lactamase_122,TEM-1,beta-lactamase,P62593,1.03038,NO,122,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.406,-2.918,0.512,4.87767,0.352,H,A,0.73,-0.54,1.581,,77.62,OPH,-1.39767,0.221079,0.00497825,1.03038 PSD95pdz3_G335D,PSD95pdz3_335,PSD95pdz3,PSD95pdz3,P31016,1.03038,NO,335,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.008,-3.15,2.142,4.76223,,,,,22.4225,,,,AOH,-1.34733,0.0758425,0.000900493,1.03038 beta-lactamase_0_L160F,beta-lactamase_0_160,TEM-1,beta-lactamase_0,P62593,1.03039,NO,160,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.977,-3.681,2.704,,0.022,,B,0.55,-0.6,0.68,,44.41,BHA,-0.936,0.0500837,0.00193775,1.03039 beta-lactamase_39_G142M,beta-lactamase_39_142,TEM-1,beta-lactamase_39,P62593,1.0304,NO,142,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.707,-4.893,4.186,,0.034,,p,0.29,-0.64,1.947,,64.69,OOO,-0.834,0.0495842,0.00060149,1.0304 PSD95pdz3_G344A,PSD95pdz3_344,PSD95pdz3,PSD95pdz3,P31016,1.0304,NO,344,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.008,-2.534,1.526,4.83855,,,,,14.06,,,,HOO,-1.10767,0.0758425,0.00078498,1.0304 beta-lactamase_0_R92T,beta-lactamase_0_92,TEM-1,beta-lactamase_0,P62593,1.03041,NO,92,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.718,-2.88,1.162,,0.479,E,B,1.2,1.36,2.331,,65.38,BBH,-1.50367,0.0500837,0.00429626,1.03041 Pab1_Q194S,Pab1_194,Pab1,Pab1,P04147,1.03044,NO,194,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.179,-3.334,1.155,,,,,,,,,,OPA,-1.59767,0.175299,0.0016145,1.03044 beta-lactamase_A15S,beta-lactamase_15,TEM-1,beta-lactamase,P62593,1.03045,NO,15,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.654,-2.078,0.424,,,,,,,31.998,31.998,93.01,HHH,-2.10833,0.221079,0.00248966,1.03045 beta-lactamase_0_V29S,beta-lactamase_0_29,TEM-1,beta-lactamase_0,P62593,1.03047,NO,29,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-2.856,-2.693,-0.163,,0.733,H,A,0.44,-0.78,21.916,21.916,93.01,HHB,-2.24733,0.0500837,0.00318969,1.03047 beta-lactamase_156_T27I,beta-lactamase_156_27,TEM-1,beta-lactamase_156,P62593,1.03047,NO,27,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.905,-3.752,1.847,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.111618,0.00306559,1.03047 Pab1_P135Q,Pab1_135,Pab1,Pab1,P04147,1.03047,NO,135,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.457,-2.566,1.109,,,,,,,6.41,,81.8,BOA,-1.53367,0.175299,0.00148028,1.03047 kka2_1:8_A247V,kka2_1:8_247,Kka2,kka2_1:8,P00552,1.03048,NO,247,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.459,-2.971,0.512,,1.01,S,A,0.46,0.65,18.904,18.904,92.05,HHH,-2.197,0.100394,0.0102428,1.03048 kka2_1:8_A247V,kka2_1:8_247,Kka2,kka2_1:8,P00552,1.03048,NO,247,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.459,-2.971,0.512,,1.01,S,A,0.46,0.65,18.904,18.904,92.05,HHH,-2.197,0.100394,0.0102428,1.03048 beta-lactamase_0_E108L,beta-lactamase_0_108,TEM-1,beta-lactamase_0,P62593,1.03052,NO,108,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.46,-3.653,2.193,,0.572,G,A,1.04,1.87,8.602,8.602,72.73,PAB,-1.437,0.0500837,0.00413372,1.03052 beta-lactamase_156_A170S,beta-lactamase_156_170,TEM-1,beta-lactamase_156,P62593,1.03052,NO,170,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.237,-3.188,1.951,,0.126,,L,0.46,-0.35,3.7,,64.69,AHH,-1.63267,0.111618,0.00431903,1.03052 PSD95pdz3_S371V,PSD95pdz3_371,PSD95pdz3,PSD95pdz3,P31016,1.03053,NO,371,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.86,-3.012,1.152,5.19744,,,,,17.1117,3.854,,87.71,HPB,-1.598,0.0758425,0.000847873,1.03053 beta-lactamase_156_R118H,beta-lactamase_156_118,TEM-1,beta-lactamase_156,P62593,1.03054,NO,118,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.413,-4.71,2.297,,0.457,H,A,1.2,1.39,2.231,,77.62,HBA,-1.785,0.111618,0.00538794,1.03054 beta-lactamase_625_E61K,beta-lactamase_625_61,TEM-1,beta-lactamase_625,P62593,1.03054,NO,61,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.115,-3.46,1.345,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.213352,0.00440955,1.03054 beta-lactamase_39_E279Q,beta-lactamase_39_279,TEM-1,beta-lactamase_39,P62593,1.03057,NO,279,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.0495842,0.0192826,1.03057 beta-lactamase_39_R159F,beta-lactamase_39_159,TEM-1,beta-lactamase_39,P62593,1.03058,NO,159,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-0.94,-4.255,3.315,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.0495842,0.00108472,1.03058 PSD95pdz3_Q384P,PSD95pdz3_384,PSD95pdz3,PSD95pdz3,P31016,1.03058,NO,384,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-1.699,-3.336,1.637,5.49339,,,,,23.54,,,,OPP,-1.41333,0.0758425,0.000216736,1.03058 beta-lactamase_156_P25F,beta-lactamase_156_25,TEM-1,beta-lactamase_156,P62593,1.03059,NO,25,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.526,-4.406,2.88,,0.624,H,A,0.52,0.14,1.079,,73.08,BOA,-2.15367,0.111618,0.00347571,1.03059 beta-lactamase_156_M270C,beta-lactamase_156_270,TEM-1,beta-lactamase_156,P62593,1.03062,NO,270,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.111618,0.00767762,1.03062 beta-lactamase_0_G240D,beta-lactamase_0_240,TEM-1,beta-lactamase_0,P62593,1.03065,NO,240,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.0500837,0.00591201,1.03065 beta-lactamase_625_M180Q,beta-lactamase_625_180,TEM-1,beta-lactamase_625,P62593,1.03065,NO,180,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-2.795,-3.924,1.129,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.213352,0.00552048,1.03065 beta-lactamase_625_S283N,beta-lactamase_625_283,TEM-1,beta-lactamase_625,P62593,1.03066,NO,283,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.213352,0.0429138,1.03066 beta-lactamase_T138N,beta-lactamase_138,TEM-1,beta-lactamase,P62593,1.03066,NO,138,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.506,-2.961,0.455,5.52585,0.662,H,A,0.3,-0.03,30.445,30.445,73.78,HPP,-1.81233,0.221079,0.00487868,1.03066 beta-lactamase_39_E238H,beta-lactamase_39_238,TEM-1,beta-lactamase_39,P62593,1.03067,NO,238,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.0495842,0.00743256,1.03067 beta-lactamase_39_E279K,beta-lactamase_39_279,TEM-1,beta-lactamase_39,P62593,1.03067,NO,279,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.0495842,0.0192826,1.03067 beta-lactamase_625_K190D,beta-lactamase_625_190,TEM-1,beta-lactamase_625,P62593,1.03069,NO,190,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.994,-3.691,1.697,,0.371,H,A,2.34,0.16,29.753,29.753,77.62,BBH,-1.64167,0.213352,0.00574527,1.03069 beta-lactamase_156_A215S,beta-lactamase_156_215,TEM-1,beta-lactamase_156,P62593,1.0307,NO,215,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.503,-2.232,0.729,,,,a,0.46,-0.93,3.583,,74.48,HHO,-1.42633,0.111618,0.00544007,1.0307 beta-lactamase_0_D33F,beta-lactamase_0_33,TEM-1,beta-lactamase_0,P62593,1.03073,NO,33,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.321,-4.288,1.967,,0.366,H,A,0.75,0.33,12.514,12.514,77.62,BAH,-2.12133,0.0500837,0.00435556,1.03073 beta-lactamase_156_E26L,beta-lactamase_156_26,TEM-1,beta-lactamase_156,P62593,1.03073,NO,26,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.454,-2.726,0.272,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.111618,0.00297948,1.03073 beta-lactamase_39_I244E,beta-lactamase_39_244,TEM-1,beta-lactamase_39,P62593,1.03073,NO,244,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.555,-3.795,2.24,,,E,B,0.48,-0.84,1.325,,77.62,OHH,-1.385,0.0495842,0.00605379,1.03073 beta-lactamase_A225Q,beta-lactamase_225,TEM-1,beta-lactamase,P62593,1.03073,NO,225,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.845,-2.909,1.064,6.5181,1,T,B,0.58,-0.38,4.077,,74.48,OHO,-1.39967,0.221079,0.00465057,1.03073 beta-lactamase_A280E,beta-lactamase_280,TEM-1,beta-lactamase,P62593,1.03073,NO,280,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.708,-2.682,0.974,4.74932,0.379,H,A,0.52,-0.72,1.785,,68.18,OHP,-1.66433,0.221079,0.0530888,1.03073 beta-lactamase_39_C75M,beta-lactamase_39_75,TEM-1,beta-lactamase_39,P62593,1.03077,NO,75,C,M,CM,Special,Hydrophobic,5.07,5.74,0.67,196,121,149,28,108.5,162.9,54.4,-1.245,-4.597,3.352,,,H,A,0.46,-0.87,2.369,,50,HOO,-1.24333,0.0495842,0.0034616,1.03077 beta-lactamase_R202Q,beta-lactamase_202,TEM-1,beta-lactamase,P62593,1.03077,NO,202,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.292,-1.95,0.658,5.16273,0.188,H,A,0.68,0.62,1.918,,77.62,PBP,-1.54767,0.221079,0.00321899,1.03077 kka2_1:2_D154V,kka2_1:2_154,Kka2,kka2_1:2,P00552,1.0308,NO,154,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.876,-3.815,2.939,,0.457,,b,0.29,1.48,3.631,,52.65,HAP,-1.52467,0.295029,0.00292633,1.0308 Pab1_L191I,Pab1_191,Pab1,Pab1,P04147,1.0308,NO,191,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.2,-2.846,1.646,,0.204,E,B,,2.24,,,,HHP,-1.20133,0.175299,0.000583797,1.0308 beta-lactamase_0_M67I,beta-lactamase_0_67,TEM-1,beta-lactamase_0,P62593,1.03082,NO,67,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-2.231,-2.93,0.699,,0.006,G,P,0.55,-0.81,24.165,24.165,65.03,HHP,-1.502,0.0500837,0.00409753,1.03082 beta-lactamase_39_A235N,beta-lactamase_39_235,TEM-1,beta-lactamase_39,P62593,1.03084,NO,235,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.266,-3.746,2.48,,0.32,E,B,0.46,-0.86,1.344,,50,OHO,-0.89,0.0495842,0.00493474,1.03084 beta-lactamase_39_D33Q,beta-lactamase_39_33,TEM-1,beta-lactamase_39,P62593,1.03084,NO,33,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.321,-2.638,0.317,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.0495842,0.00435556,1.03084 beta-lactamase_0_G76E,beta-lactamase_0_76,TEM-1,beta-lactamase_0,P62593,1.03085,NO,76,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.189,-3.614,2.425,,,H,A,0.29,-0.67,1.188,,67.83,OOH,-1.22267,0.0500837,0.00476637,1.03085 beta-lactamase_0_A84C,beta-lactamase_0_84,TEM-1,beta-lactamase_0,P62593,1.03086,NO,84,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.651,-5.003,3.352,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.0500837,0.00503822,1.03086 beta-lactamase_156_E108K,beta-lactamase_156_108,TEM-1,beta-lactamase_156,P62593,1.03087,NO,108,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.46,-2.182,0.722,,0.572,G,A,1.04,1.87,8.602,8.602,72.73,PAB,-1.437,0.111618,0.00413372,1.03087 beta-lactamase_625_E26F,beta-lactamase_625_26,TEM-1,beta-lactamase_625,P62593,1.03087,NO,26,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.454,-4.297,1.843,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.213352,0.00297948,1.03087 beta-lactamase_0_G194A,beta-lactamase_0_194,TEM-1,beta-lactamase_0,P62593,1.03088,NO,194,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.396,-2.558,1.162,,0.276,S,b,0.29,0.36,3.017,,67.83,POA,-1.832,0.0500837,0.00392163,1.03088 kka2_1:4_H106V,kka2_1:4_106,Kka2,kka2_1:4,P00552,1.03088,NO,106,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-3.13,-3.002,-0.128,,1.065,.,a,0.17,-0.95,16.74,16.74,71.59,PBH,-2.10433,0.168804,0.00730778,1.03088 beta-lactamase_39_I285L,beta-lactamase_39_285,TEM-1,beta-lactamase_39,P62593,1.03089,NO,285,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.0495842,0.101555,1.03089 beta-lactamase_625_S221D,beta-lactamase_625_221,TEM-1,beta-lactamase_625,P62593,1.03089,NO,221,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.754,-3.645,1.891,,0.624,H,A,0.27,-0.2,1.495,,74.48,BPH,-1.59967,0.213352,0.0046094,1.03089 beta-lactamase_0_P105G,beta-lactamase_0_105,TEM-1,beta-lactamase_0,P62593,1.03091,NO,105,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.813,-3.321,2.508,,0.226,T,A,0.52,0.8,3.48,,63.29,POH,-1.01533,0.0500837,0.0011981,1.03091 kka2_1:8_L53M,kka2_1:8_53,Kka2,kka2_1:8,P00552,1.03091,NO,53,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-2.681,-3.617,0.936,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.100394,0.00671168,1.03091 kka2_1:8_L53M,kka2_1:8_53,Kka2,kka2_1:8,P00552,1.03091,NO,53,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-2.681,-3.617,0.936,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.100394,0.00671168,1.03091 beta-lactamase_2500_E210W,beta-lactamase_2500_210,TEM-1,beta-lactamase_2500,P62593,1.03094,NO,210,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.319,-5.437,3.118,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.361275,0.00663582,1.03094 gb1_D272M,gb1_272,gb1,gb1,P06654,1.03094,NO,272,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.457,-4.677,3.22,,,,,,,0.234,,11.83,HAA,-1.54533,0.177985,0.00218257,1.03094 E1_Ubiquitin_F45R,E1_Ubiquitin_45,Uba1,E1_Ubiquitin,P0CG63,1.03095,NO,45,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.149,-3.975,2.826,,0.26,E,B,,-0.99,,,,HHH,-1.316,0.18783,0.00193245,1.03095 E1_Ubiquitin_L71A,E1_Ubiquitin_71,Uba1,E1_Ubiquitin,P0CG63,1.03095,NO,71,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.039,-2.895,1.856,,0.591,E,B,,-0.69,,,,BHB,-1.19433,0.18783,0.00148349,1.03095 E1_Ubiquitin_Q40I,E1_Ubiquitin_40,Uba1,E1_Ubiquitin,P0CG63,1.03095,NO,40,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-1.48,-3.923,2.443,,0.387,G,A,,0.03,,,,OPP,-1.365,0.18783,0.0037961,1.03095 beta-lactamase_625_E46A,beta-lactamase_625_46,TEM-1,beta-lactamase_625,P62593,1.03097,NO,46,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.94,-2.586,0.646,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.213352,0.00427568,1.03097 WW_domain_V171F,WW_domain_171,Yap65,WW_domain,P46937,1.03098,NO,171,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.547,-3.716,2.169,,,,,,,3.459,,70.24,AHO,-1.265,0.153962,0.00184125,1.03098 kka2_1:2_Q252C,kka2_1:2_252,Kka2,kka2_1:2,P00552,1.03099,NO,252,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.63,-5.184,2.554,,0.906,H,A,0.64,0.35,5.613,,92.05,PPB,-2.20733,0.295029,0.0121001,1.03099 beta-lactamase_0_E195T,beta-lactamase_0_195,TEM-1,beta-lactamase_0,P62593,1.031,NO,195,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.186,-2.956,0.77,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.0500837,0.00496565,1.031 beta-lactamase_2500_H110Y,beta-lactamase_2500_110,TEM-1,beta-lactamase_2500,P62593,1.031,NO,110,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-1.706,-2.513,0.807,,0.341,G,a,0.17,1.08,31.31,31.31,64.69,BBH,-1.73333,0.361275,0.00441499,1.031 beta-lactamase_0_E26S,beta-lactamase_0_26,TEM-1,beta-lactamase_0,P62593,1.03102,NO,26,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.454,-3.34,0.886,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.0500837,0.00297948,1.03102 PSD95pdz3_H317P,PSD95pdz3_317,PSD95pdz3,PSD95pdz3,P31016,1.03102,NO,317,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-1.627,-3.561,1.934,6.19713,,,,,25.885,,,,HBB,-1.613,0.0758425,0.00111619,1.03102 beta-lactamase_39_T69M,beta-lactamase_39_69,TEM-1,beta-lactamase_39,P62593,1.03103,NO,69,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-0.973,-4.54,3.567,,,G,A,0.22,-1.24,4.194,,93.01,PPH,-1.01833,0.0495842,0.00127498,1.03103 beta-lactamase_39_C75T,beta-lactamase_39_75,TEM-1,beta-lactamase_39,P62593,1.03105,NO,75,C,T,CT,Special,Polar,5.07,5.6,0.53,149,121,119,-2,108.5,116.1,7.6,-1.245,-3.423,2.178,,,H,A,0.46,-0.87,2.369,,50,HOO,-1.24333,0.0495842,0.0034616,1.03105 beta-lactamase_39_T107V,beta-lactamase_39_107,TEM-1,beta-lactamase_39,P62593,1.03105,NO,107,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.117,-3.226,2.109,,,G,A,0.22,-0.06,2.686,,67.83,HPA,-1.265,0.0495842,0.00239347,1.03105 beta-lactamase_39_R91A,beta-lactamase_39_91,TEM-1,beta-lactamase_39,P62593,1.03106,NO,91,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.392,-2.55,1.158,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.0495842,0.00380226,1.03106 beta-lactamase_39_Y44M,beta-lactamase_39_44,TEM-1,beta-lactamase_39,P62593,1.03106,NO,44,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-2.547,-2.521,-0.026,,,E,B,0.21,-0.45,2.683,,73.78,OHH,-1.86267,0.0495842,0.00426364,1.03106 beta-lactamase_625_R273D,beta-lactamase_625_273,TEM-1,beta-lactamase_625,P62593,1.03107,NO,273,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.314,-3.543,1.229,,0.564,H,A,1.2,1.57,1.455,,73.78,ABP,-1.841,0.213352,0.0077952,1.03107 beta-lactamase_625_A211D,beta-lactamase_625_211,TEM-1,beta-lactamase_625,P62593,1.03108,NO,211,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.896,-1.934,0.038,,0.369,T,A,0.46,-0.69,2.061,,77.62,AHA,-1.94633,0.213352,0.00648183,1.03108 PSD95pdz3_S361N,PSD95pdz3_361,PSD95pdz3,PSD95pdz3,P31016,1.03108,NO,361,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.519,-2.905,1.386,4.8722,,,,,16.4533,,,,HPH,-1.47167,0.0758425,0.00055296,1.03108 beta-lactamase_0_D252S,beta-lactamase_0_252,TEM-1,beta-lactamase_0,P62593,1.03113,NO,252,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.94,,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.0500837,0.00575769,1.03113 beta-lactamase_156_T193R,beta-lactamase_156_193,TEM-1,beta-lactamase_156,P62593,1.03113,NO,193,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.914,-4.014,2.1,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.111618,0.00482669,1.03113 beta-lactamase_156_I93E,beta-lactamase_156_93,TEM-1,beta-lactamase_156,P62593,1.03114,NO,93,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.401,-3.886,2.485,,0.128,E,B,0.48,0.44,1.524,,67.83,BHB,-1.873,0.111618,0.00527066,1.03114 PSD95pdz3_A376V,PSD95pdz3_376,PSD95pdz3,PSD95pdz3,P31016,1.03115,NO,376,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.307,-2.76,1.453,4.72134,,,,,17.108,,,,HHH,-1.49567,0.0758425,0.000341232,1.03115 beta-lactamase_39_I285P,beta-lactamase_39_285,TEM-1,beta-lactamase_39,P62593,1.03118,NO,285,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.0495842,0.101555,1.03118 beta-lactamase_S122D,beta-lactamase_122,TEM-1,beta-lactamase,P62593,1.03119,NO,122,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.406,-2.549,0.143,4.87767,0.352,H,A,0.73,-0.54,1.581,,77.62,OPH,-1.39767,0.221079,0.00497825,1.03119 PSD95pdz3_E352H,PSD95pdz3_352,PSD95pdz3,PSD95pdz3,P31016,1.03119,NO,352,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.587,-4.164,2.577,5.49659,,,,,24.2,2.525,,86.88,OAH,-1.314,0.0758425,0.000892231,1.03119 beta-lactamase_156_I244T,beta-lactamase_156_244,TEM-1,beta-lactamase_156,P62593,1.0312,NO,244,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.555,-2.572,1.017,,,E,B,0.48,-0.84,1.325,,77.62,OHH,-1.385,0.111618,0.00605379,1.0312 beta-lactamase_0_V157I,beta-lactamase_0_157,TEM-1,beta-lactamase_0,P62593,1.03121,NO,157,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.751,-2.621,0.87,,0.308,S,a,0.44,-0.75,3.106,,69.58,BHP,-2.00767,0.0500837,0.00506849,1.03121 beta-lactamase_156_L219I,beta-lactamase_156_219,TEM-1,beta-lactamase_156,P62593,1.03121,NO,219,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.313,-1.692,0.379,,,I,A,0.55,-0.51,2.321,,74.48,HHB,-1.21533,0.111618,0.00664345,1.03121 PSD95pdz3_G356Y,PSD95pdz3_356,PSD95pdz3,PSD95pdz3,P31016,1.03121,NO,356,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.008,-4.069,3.061,4.8656,,,,,11.9575,,,,BOA,-1.22933,0.0758425,0.000623061,1.03121 beta-lactamase_156_V106M,beta-lactamase_156_106,TEM-1,beta-lactamase_156,P62593,1.03122,NO,106,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.218,-3.026,1.808,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.111618,0.00304168,1.03122 PSD95pdz3_N326A,PSD95pdz3_326,PSD95pdz3,PSD95pdz3,P31016,1.03122,NO,326,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-1.41,-2.984,1.574,5.52537,,,,,19.0688,,,,HPH,-1.52133,0.0758425,0.00101078,1.03122 beta-lactamase_39_E61C,beta-lactamase_39_61,TEM-1,beta-lactamase_39,P62593,1.03123,NO,61,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.115,-5.186,3.071,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.0495842,0.00440955,1.03123 beta-lactamase_625_E272H,beta-lactamase_625_272,TEM-1,beta-lactamase_625,P62593,1.03123,NO,272,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.213352,0.00545371,1.03123 beta-lactamase_156_R273M,beta-lactamase_156_273,TEM-1,beta-lactamase_156,P62593,1.03124,NO,273,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.314,-4.698,2.384,,0.564,H,A,1.2,1.57,20.248,20.248,73.78,ABP,-1.841,0.111618,0.0077952,1.03124 beta-lactamase_39_T112G,beta-lactamase_39_112,TEM-1,beta-lactamase_39,P62593,1.03126,NO,112,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.186,-1.822,-0.364,,0.921,T,A,0.22,1.06,2.87,,73.78,HPA,-1.925,0.0495842,0.00531334,1.03126 beta-lactamase_39_S233M,beta-lactamase_39_233,TEM-1,beta-lactamase_39,P62593,1.03127,NO,233,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.886,-4.626,2.74,,0.016,E,B,0.27,-1.01,5.361,,77.62,BPO,-1.17267,0.0495842,0.00311415,1.03127 beta-lactamase_625_S51D,beta-lactamase_625_51,TEM-1,beta-lactamase_625,P62593,1.03127,NO,51,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.526,-2.756,1.23,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.213352,0.00504821,1.03127 kka2_1:2_P12V,kka2_1:2_12,Kka2,kka2_1:2,P00552,1.03129,NO,12,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.853,-3.479,2.626,,,.,B,0.52,1.25,0.261,,48.11,POH,-1.80767,0.295029,0.00500011,1.03129 beta-lactamase_39_R41I,beta-lactamase_39_41,TEM-1,beta-lactamase_39,P62593,1.03131,NO,41,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-0.942,-4.008,3.066,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.0495842,0.00123327,1.03131 beta-lactamase_0_N50Y,beta-lactamase_0_50,TEM-1,beta-lactamase_0,P62593,1.03132,NO,50,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-2.979,-4.3,1.321,,0.912,T,A,0.61,1.24,9.874,9.874,77.62,HPP,-2.134,0.0500837,0.0047211,1.03132 beta-lactamase_625_I285H,beta-lactamase_625_285,TEM-1,beta-lactamase_625,P62593,1.03132,NO,285,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.845,-3.788,1.943,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.213352,0.101555,1.03132 beta-lactamase_K144K,beta-lactamase_144,TEM-1,beta-lactamase,P62593,1.03132,NO,144,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-2.388,-2.388,,6.02507,0.863,H,A,2.81,1.27,0.515,,77.62,OBA,-1.904,0.221079,0.00481141,1.03132 beta-lactamase_39_R162Q,beta-lactamase_39_162,TEM-1,beta-lactamase_39,P62593,1.03133,NO,162,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.016,-3.59,2.574,,0.124,S,B,1.2,-0.37,31.656,31.656,64.69,ABH,-1.25,0.0495842,0.000561334,1.03133 beta-lactamase_625_E26K,beta-lactamase_625_26,TEM-1,beta-lactamase_625,P62593,1.03133,NO,26,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.454,-3.374,0.92,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.213352,0.00297948,1.03133 kka2_1:8_D23L,kka2_1:8_23,Kka2,kka2_1:8,P00552,1.03133,NO,23,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.459,-2.907,0.448,,0.695,E,B,0.75,-0.65,,,65.53,HAH,-1.94033,0.100394,0.007195,1.03133 kka2_1:8_D23L,kka2_1:8_23,Kka2,kka2_1:8,P00552,1.03133,NO,23,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.459,-2.907,0.448,,0.695,E,B,0.75,-0.65,,,65.53,HAH,-1.94033,0.100394,0.007195,1.03133 beta-lactamase_T131T,beta-lactamase_131,TEM-1,beta-lactamase,P62593,1.03135,NO,131,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.328,-1.328,,5.0548,,H,A,0.53,-0.69,3.306,,67.48,PPH,-1.00867,0.221079,0.00345886,1.03135 kka2_1:2_D134F,kka2_1:2_134,Kka2,kka2_1:2,P00552,1.03135,NO,134,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.969,-4.314,3.345,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.295029,0.00270812,1.03135 beta-lactamase_0_A34Q,beta-lactamase_0_34,TEM-1,beta-lactamase_0,P62593,1.03137,NO,34,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.059,-4.16,2.101,,,H,A,0.46,-0.54,3.998,,73.78,AHA,-1.74967,0.0500837,0.00407913,1.03137 beta-lactamase_39_E26Y,beta-lactamase_39_26,TEM-1,beta-lactamase_39,P62593,1.03138,NO,26,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.454,-4.272,1.818,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.0495842,0.00297948,1.03138 beta-lactamase_I171I,beta-lactamase_171,TEM-1,beta-lactamase,P62593,1.0314,NO,171,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-2.431,-2.431,,5.22771,0.361,,B,1,0.53,1.66,,77.62,HHO,-1.55533,0.221079,0.00623355,1.0314 PSD95pdz3_H317E,PSD95pdz3_317,PSD95pdz3,PSD95pdz3,P31016,1.03141,NO,317,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-1.627,-2.897,1.27,6.19713,,,,,25.885,,,,HBB,-1.613,0.0758425,0.00111619,1.03141 beta-lactamase_156_I93Q,beta-lactamase_156_93,TEM-1,beta-lactamase_156,P62593,1.03147,NO,93,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.401,-4.315,2.914,,0.128,E,B,0.48,0.44,1.524,,67.83,BHB,-1.873,0.111618,0.00527066,1.03147 beta-lactamase_0_T112R,beta-lactamase_0_112,TEM-1,beta-lactamase_0,P62593,1.03148,NO,112,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.186,-3.88,1.694,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.0500837,0.00531334,1.03148 beta-lactamase_2500_A211H,beta-lactamase_2500_211,TEM-1,beta-lactamase_2500,P62593,1.03149,NO,211,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.896,-3.336,1.44,,0.369,T,A,0.46,-0.69,2.061,,77.62,AHA,-1.94633,0.361275,0.00648183,1.03149 beta-lactamase_F22E,beta-lactamase_22,TEM-1,beta-lactamase,P62593,1.03149,NO,22,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-2.676,-3.602,0.926,,,,,,,1.616,,73.08,HHH,-2.03233,0.221079,0.00262842,1.03149 beta-lactamase_T112Y,beta-lactamase_112,TEM-1,beta-lactamase,P62593,1.03149,NO,112,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.186,-4.422,2.236,6.47162,0.921,T,A,0.77,1.06,2.04,,73.78,HPA,-1.925,0.221079,0.00531334,1.03149 kka2_1:8_G88A,kka2_1:8_88,Kka2,kka2_1:8,P00552,1.03149,NO,88,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.689,-2.52,0.831,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.100394,0.00685559,1.03149 kka2_1:8_G88A,kka2_1:8_88,Kka2,kka2_1:8,P00552,1.03149,NO,88,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.689,-2.52,0.831,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.100394,0.00685559,1.03149 PSD95pdz3_R354T,PSD95pdz3_354,PSD95pdz3,PSD95pdz3,P31016,1.0315,NO,354,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.582,-3.103,1.521,6.21887,,,,,23.7791,,,,HBB,-1.44833,0.0758425,0.000650924,1.0315 beta-lactamase_2500_F149W,beta-lactamase_2500_149,TEM-1,beta-lactamase_2500,P62593,1.03153,NO,149,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.299,-2.98,1.681,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.361275,0.00418462,1.03153 beta-lactamase_625_L49I,beta-lactamase_625_49,TEM-1,beta-lactamase_625,P62593,1.03153,NO,49,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.897,-3.523,1.626,,0.131,T,A,0.55,0.04,3.112,,64.69,AHP,-1.99233,0.213352,0.00401477,1.03153 beta-lactamase_0_A247I,beta-lactamase_0_247,TEM-1,beta-lactamase_0,P62593,1.03155,NO,247,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.0500837,0.00611275,1.03155 kka2_1:4_A64C,kka2_1:4_64,Kka2,kka2_1:4,P00552,1.03156,NO,64,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.496,-4.794,3.298,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.168804,0.00705578,1.03156 PSD95pdz3_G344K,PSD95pdz3_344,PSD95pdz3,PSD95pdz3,P31016,1.03156,NO,344,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.008,-3.364,2.356,4.83855,,,,,14.06,,,,HOO,-1.10767,0.0758425,0.00078498,1.03156 beta-lactamase_39_F228K,beta-lactamase_39_228,TEM-1,beta-lactamase_39,P62593,1.03158,NO,228,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-2.342,-2.864,0.522,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.0495842,0.0046669,1.03158 kka2_1:8_A87L,kka2_1:8_87,Kka2,kka2_1:8,P00552,1.03158,NO,87,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.917,-3.08,1.163,,1.039,S,L,0.46,1.57,16.115,16.115,65.53,AHO,-1.822,0.100394,0.00791281,1.03158 kka2_1:8_A87L,kka2_1:8_87,Kka2,kka2_1:8,P00552,1.03158,NO,87,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.917,-3.08,1.163,,1.039,S,L,0.46,1.57,16.115,16.115,65.53,AHO,-1.822,0.100394,0.00791281,1.03158 beta-lactamase_625_A200K,beta-lactamase_625_200,TEM-1,beta-lactamase_625,P62593,1.0316,NO,200,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.878,-2.669,0.791,,0.757,H,A,0.46,-0.19,12.672,12.672,77.62,HHP,-2.001,0.213352,0.0060056,1.0316 gb1_T270R,gb1_270,gb1,gb1,P06654,1.0316,NO,270,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-3.15,-3.639,0.489,,,,,,,1.326,,45.54,HPH,-1.843,0.177985,0.00223707,1.0316 beta-lactamase_156_V72M,beta-lactamase_156_72,TEM-1,beta-lactamase_156,P62593,1.03164,NO,72,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.658,-4.404,2.746,,,H,A,0.44,-1.03,1.92,,65.73,BHH,-1.32167,0.111618,0.00501194,1.03164 beta-lactamase_2500_S221Q,beta-lactamase_2500_221,TEM-1,beta-lactamase_2500,P62593,1.03164,NO,221,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.754,-3.871,2.117,,0.624,H,A,0.27,-0.2,1.971,,74.48,BPH,-1.59967,0.361275,0.0046094,1.03164 kka2_1:8_T72P,kka2_1:8_72,Kka2,kka2_1:8,P00552,1.03164,NO,72,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.38,-4.008,1.628,,0.784,H,A,0.22,0.29,3.603,,65.53,HPP,-2.238,0.100394,0.00750756,1.03164 kka2_1:8_T72P,kka2_1:8_72,Kka2,kka2_1:8,P00552,1.03164,NO,72,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.38,-4.008,1.628,,0.784,H,A,0.22,0.29,3.603,,65.53,HPP,-2.238,0.100394,0.00750756,1.03164 beta-lactamase_39_L74I,beta-lactamase_39_74,TEM-1,beta-lactamase_39,P62593,1.03166,NO,74,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.296,-2.577,1.281,,,H,A,0.55,-0.91,1.581,,50,HHO,-1.34933,0.0495842,0.00493255,1.03166 beta-lactamase_39_P224G,beta-lactamase_39_224,TEM-1,beta-lactamase_39,P62593,1.03167,NO,224,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.893,-3.351,2.458,,0.383,,B,0.52,-0.3,3.169,,74.48,HOH,-1.26433,0.0495842,0.00189564,1.03167 beta-lactamase_625_S201H,beta-lactamase_625_201,TEM-1,beta-lactamase_625,P62593,1.03167,NO,201,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.183,-4.595,3.412,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.213352,0.00198815,1.03167 beta-lactamase_L196T,beta-lactamase_196,TEM-1,beta-lactamase,P62593,1.03168,NO,196,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-2.478,-2.588,0.11,,0.518,S,A,0.55,1.35,,,77.62,AHH,-1.839,0.221079,0.00512144,1.03168 beta-lactamase_39_F149K,beta-lactamase_39_149,TEM-1,beta-lactamase_39,P62593,1.03169,NO,149,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.299,-3.859,2.56,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.0495842,0.00418462,1.03169 beta-lactamase_39_V29C,beta-lactamase_39_29,TEM-1,beta-lactamase_39,P62593,1.03172,NO,29,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-2.856,-5.117,2.261,,0.733,H,A,0.44,-0.78,1.287,,93.01,HHB,-2.24733,0.0495842,0.00318969,1.03172 beta-lactamase_39_I93Q,beta-lactamase_39_93,TEM-1,beta-lactamase_39,P62593,1.03174,NO,93,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.401,-4.315,2.914,,0.128,E,B,0.48,0.44,1.757,,67.83,BHB,-1.873,0.0495842,0.00527066,1.03174 beta-lactamase_L196R,beta-lactamase_196,TEM-1,beta-lactamase,P62593,1.03174,NO,196,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-2.478,-2.59,0.112,,0.518,S,A,0.55,1.35,,,77.62,AHH,-1.839,0.221079,0.00512144,1.03174 kka2_1:4_M178A,kka2_1:4_178,Kka2,kka2_1:4,P00552,1.03175,NO,178,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-3.206,-2.643,-0.563,,0.554,.,b,0.55,0.68,9.913,9.913,71.59,BHO,-2.154,0.168804,0.00717253,1.03175 kka2_1:4_Q100I,kka2_1:4_100,Kka2,kka2_1:4,P00552,1.03175,NO,100,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.77,-3.068,0.298,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.168804,0.0066405,1.03175 kka2_1:4_P98M,kka2_1:4_98,Kka2,kka2_1:4,P00552,1.03176,NO,98,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.526,-4.804,3.278,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.168804,0.00622754,1.03176 beta-lactamase_39_G154N,beta-lactamase_39_154,TEM-1,beta-lactamase_39,P62593,1.0318,NO,154,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.823,-3.507,2.684,,0.54,T,l,0.29,-0.56,1.151,,64.69,HOA,-1.635,0.0495842,0.00180205,1.0318 beta-lactamase_39_T131Y,beta-lactamase_39_131,TEM-1,beta-lactamase_39,P62593,1.03181,NO,131,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.328,-4.285,2.957,,,H,A,0.22,-0.69,3.306,,67.48,PPH,-1.00867,0.0495842,0.00345886,1.03181 beta-lactamase_0_Q203A,beta-lactamase_0_203,TEM-1,beta-lactamase_0,P62593,1.03182,NO,203,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.168,-2.117,-0.051,,0.47,H,A,0.64,-0.38,14.541,14.541,65.38,BPP,-1.614,0.0500837,0.00631514,1.03182 beta-lactamase_0_S266E,beta-lactamase_0_266,TEM-1,beta-lactamase_0,P62593,1.03182,NO,266,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.0500837,0.0140785,1.03182 PSD95pdz3_I389V,PSD95pdz3_389,PSD95pdz3,PSD95pdz3,P31016,1.03183,NO,389,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.628,-1.67,0.042,5.15116,,,,,14.8038,1.498,,87.71,HHH,-1.52167,0.0758425,0.00148097,1.03183 beta-lactamase_39_V259I,beta-lactamase_39_259,TEM-1,beta-lactamase_39,P62593,1.03185,NO,259,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.522,-1.739,0.217,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.0495842,0.0070773,1.03185 kka2_1:4_A108S,kka2_1:4_108,Kka2,kka2_1:4,P00552,1.03186,NO,108,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.061,-2.146,0.085,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.168804,0.00751209,1.03186 beta-lactamase_156_E26C,beta-lactamase_156_26,TEM-1,beta-lactamase_156,P62593,1.03188,NO,26,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.454,-5.02,2.566,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.111618,0.00297948,1.03188 beta-lactamase_39_G216F,beta-lactamase_39_216,TEM-1,beta-lactamase_39,P62593,1.03188,NO,216,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.477,-4.417,2.94,,0.437,I,A,0.29,-0.58,0.834,,74.48,HOO,-1.68067,0.0495842,0.00639568,1.03188 kka2_1:8_G99K,kka2_1:8_99,Kka2,kka2_1:8,P00552,1.03188,NO,99,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.596,-3.71,3.114,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.100394,0.00186055,1.03188 kka2_1:8_G99K,kka2_1:8_99,Kka2,kka2_1:8,P00552,1.03188,NO,99,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.596,-3.71,3.114,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.100394,0.00186055,1.03188 beta-lactamase_625_F58Y,beta-lactamase_625_58,TEM-1,beta-lactamase_625,P62593,1.03189,NO,58,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-2.914,-1.89,-1.024,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.213352,0.00523369,1.03189 beta-lactamase_625_K190S,beta-lactamase_625_190,TEM-1,beta-lactamase_625,P62593,1.03192,NO,190,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.994,-2.653,0.659,,0.371,H,A,2.34,0.16,29.753,29.753,77.62,BBH,-1.64167,0.213352,0.00574527,1.03192 beta-lactamase_0_H156G,beta-lactamase_0_156,TEM-1,beta-lactamase_0,P62593,1.03194,NO,156,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-3.156,-2.688,-0.468,,0.753,S,A,0.17,-0.6,23.367,23.367,77.62,ABH,-1.932,0.0500837,0.00468596,1.03194 kka2_1:2_H124P,kka2_1:2_124,Kka2,kka2_1:2,P00552,1.03194,NO,124,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-0.84,-3.908,3.068,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.295029,0.00211296,1.03194 beta-lactamase_39_P143T,beta-lactamase_39_143,TEM-1,beta-lactamase_39,P62593,1.03196,NO,143,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.967,-2.616,1.649,,0.075,H,A,0.52,-0.37,0.976,,66.78,OOB,-1.354,0.0495842,0.00114551,1.03196 kka2_1:8_Q26G,kka2_1:8_26,Kka2,kka2_1:8,P00552,1.03197,NO,26,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.18,-2.702,0.522,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.100394,0.00708962,1.03197 kka2_1:8_Q26G,kka2_1:8_26,Kka2,kka2_1:8,P00552,1.03197,NO,26,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.18,-2.702,0.522,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.100394,0.00708962,1.03197 PSD95pdz3_A343T,PSD95pdz3_343,PSD95pdz3,PSD95pdz3,P31016,1.03197,NO,343,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.307,-2.878,1.571,5.585,,,,,14.728,,,,HHO,-1.22067,0.0758425,0.000798084,1.03197 beta-lactamase_39_R92N,beta-lactamase_39_92,TEM-1,beta-lactamase_39,P62593,1.03198,NO,92,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.718,-2.988,1.27,,0.479,E,B,1.2,1.36,0.389,,65.38,BBH,-1.50367,0.0495842,0.00429626,1.03198 beta-lactamase_39_S221T,beta-lactamase_39_221,TEM-1,beta-lactamase_39,P62593,1.03199,NO,221,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.754,-3.292,1.538,,0.624,H,A,0.27,-0.2,2.69,,74.48,BPH,-1.59967,0.0495842,0.0046094,1.03199 beta-lactamase_2500_K190I,beta-lactamase_2500_190,TEM-1,beta-lactamase_2500,P62593,1.032,NO,190,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.994,-3.984,1.99,,0.371,H,A,2.34,0.16,29.753,29.753,77.62,BBH,-1.64167,0.361275,0.00574527,1.032 gb1_T275Q,gb1_275,gb1,gb1,P06654,1.032,NO,275,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.727,-3.752,2.025,,,,,,,0.511,,35.71,HPB,-1.637,0.177985,0.00606618,1.032 gb1_V280C,gb1_280,gb1,gb1,P06654,1.032,NO,280,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.764,-4.412,2.648,,,,,,,0.874,,35.71,PHP,-1.63733,0.177985,0.00321577,1.032 beta-lactamase_39_Q203F,beta-lactamase_39_203,TEM-1,beta-lactamase_39,P62593,1.03203,NO,203,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.168,-4.379,2.211,,0.47,H,A,0.64,-0.38,1.453,,65.38,BPP,-1.614,0.0495842,0.00631514,1.03203 beta-lactamase_0_F64V,beta-lactamase_0_64,TEM-1,beta-lactamase_0,P62593,1.03205,NO,64,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-0.841,-3.304,2.463,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.0500837,0.000947691,1.03205 beta-lactamase_0_W163P,beta-lactamase_0_163,TEM-1,beta-lactamase_0,P62593,1.03207,NO,163,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-1.843,-4.201,2.358,,0.467,,B,0.47,-0.5,13.843,13.843,63.99,BHA,-1.269,0.0500837,0.00418955,1.03207 beta-lactamase_625_E87I,beta-lactamase_625_87,TEM-1,beta-lactamase_625,P62593,1.03208,NO,87,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.421,-3.687,2.266,,0.048,,B,1.04,0.92,17.923,17.923,64.69,PAP,-1.969,0.213352,0.00337888,1.03208 beta-lactamase_L196I,beta-lactamase_196,TEM-1,beta-lactamase,P62593,1.03212,NO,196,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-2.478,-2.648,0.17,,0.518,S,A,0.55,1.35,,,77.62,AHH,-1.839,0.221079,0.00512144,1.03212 beta-lactamase_Q37Y,beta-lactamase_37,TEM-1,beta-lactamase,P62593,1.03212,NO,37,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.134,-4.193,2.059,5.69153,0.613,H,A,0.12,1.98,1.318,,73.08,APH,-2.06967,0.221079,0.00425833,1.03212 beta-lactamase_0_A77T,beta-lactamase_0_77,TEM-1,beta-lactamase_0,P62593,1.03213,NO,77,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.234,-2.687,1.453,,0.039,H,A,0.46,-0.56,2.591,,64.34,OHH,-1.294,0.0500837,0.00282362,1.03213 beta-lactamase_39_T186G,beta-lactamase_39_186,TEM-1,beta-lactamase_39,P62593,1.03213,NO,186,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.522,-2.403,-0.119,,0.396,H,A,0.22,-0.28,0.515,,77.62,HPP,-1.77633,0.0495842,0.00485034,1.03213 gb1_I232W,gb1_232,gb1,gb1,P06654,1.03213,NO,232,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-2.175,-5.104,2.929,,,,,,,0.766,,44.87,HHH,-2.152,0.177985,0.00580459,1.03213 kka2_1:8_D118F,kka2_1:8_118,Kka2,kka2_1:8,P00552,1.03215,NO,118,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.07,-4.414,2.344,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.100394,0.0067852,1.03215 kka2_1:8_D118F,kka2_1:8_118,Kka2,kka2_1:8,P00552,1.03215,NO,118,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.07,-4.414,2.344,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.100394,0.0067852,1.03215 PSD95pdz3_I341L,PSD95pdz3_341,PSD95pdz3,PSD95pdz3,P31016,1.03215,NO,341,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.63,-2.14,0.51,5.73946,,,,,10.3187,,,,HHH,-1.50033,0.0758425,0.000824087,1.03215 beta-lactamase_0_D212V,beta-lactamase_0_212,TEM-1,beta-lactamase_0,P62593,1.03216,NO,212,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.624,-3.608,1.984,,0.037,,b,0.75,-0.58,3.34,,74.48,HAB,-1.77667,0.0500837,0.00644302,1.03216 beta-lactamase_39_A200K,beta-lactamase_39_200,TEM-1,beta-lactamase_39,P62593,1.03216,NO,200,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.878,-2.669,0.791,,0.757,H,A,0.46,-0.19,1.54,,77.62,HHP,-2.001,0.0495842,0.0060056,1.03216 PSD95pdz3_F340G,PSD95pdz3_340,PSD95pdz3,PSD95pdz3,P31016,1.03216,NO,340,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.524,-3.265,1.741,5.79283,,,,,11.8045,,,,PHH,-1.55767,0.0758425,0.000836987,1.03216 beta-lactamase_2500_I45L,beta-lactamase_2500_45,TEM-1,beta-lactamase_2500,P62593,1.03217,NO,45,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-2.421,-2.39,-0.031,,,E,B,0.48,-0.3,3.793,,77.62,HHA,-2.30267,0.361275,0.00452842,1.03217 beta-lactamase_39_A124G,beta-lactamase_39_124,TEM-1,beta-lactamase_39,P62593,1.03217,NO,124,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.181,-3.186,2.005,,,H,A,0.46,-0.9,1.367,,64.34,HHH,-1.152,0.0495842,0.00481399,1.03217 Pab1_A199C,Pab1_199,Pab1,Pab1,P04147,1.03217,NO,199,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.53,-4.619,3.089,,,,,,,1.479,,80.42,HHO,-1.50467,0.175299,0.00145024,1.03217 Pab1_P200F,Pab1_200,Pab1,Pab1,P04147,1.03217,NO,200,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.871,-4.024,2.153,,,,,,,3.877,,80.59,HOO,-1.7005,0.175299,0.00190795,1.03217 beta-lactamase_39_M270I,beta-lactamase_39_270,TEM-1,beta-lactamase_39,P62593,1.03222,NO,270,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.0495842,0.00767762,1.03222 beta-lactamase_R118A,beta-lactamase_118,TEM-1,beta-lactamase,P62593,1.03222,NO,118,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.413,-1.798,-0.615,5.8227,0.457,H,A,0.68,1.39,2.144,,77.62,HBA,-1.785,0.221079,0.00538794,1.03222 beta-lactamase_156_E87D,beta-lactamase_156_87,TEM-1,beta-lactamase_156,P62593,1.03226,NO,87,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.421,-2.265,0.844,,0.048,,B,1.04,0.92,1.754,,64.69,PAP,-1.969,0.111618,0.00337888,1.03226 beta-lactamase_625_K190C,beta-lactamase_625_190,TEM-1,beta-lactamase_625,P62593,1.03226,NO,190,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.994,-5.082,3.088,,0.371,H,A,2.34,0.16,29.753,29.753,77.62,BBH,-1.64167,0.213352,0.00574527,1.03226 Ubiquitin_G53A,Ubiquitin_53,Uba1,Ubiquitin,P0CG48,1.03226,NO,53,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.544,-2.574,1.03,5.32628,0.805,T,A,,-0.23,,,,AOB,-1.67033,0.205827,0.000662865,1.03226 Ubiquitin_G53D,Ubiquitin_53,Uba1,Ubiquitin,P0CG48,1.03226,NO,53,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.544,-2.831,1.287,5.32628,0.805,T,A,,-0.23,,,,AOB,-1.67033,0.205827,0.000662865,1.03226 Ubiquitin_G53R,Ubiquitin_53,Uba1,Ubiquitin,P0CG48,1.03226,NO,53,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.544,-3.917,2.373,5.32628,0.805,T,A,,-0.23,,,,AOB,-1.67033,0.205827,0.000662865,1.03226 Ubiquitin_P37K,Ubiquitin_37,Uba1,Ubiquitin,P0CG48,1.03226,NO,37,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.275,-3.534,2.259,5.06918,0.323,,B,,-0.09,,,,HOO,-1.49,0.205827,0.000600764,1.03226 Ubiquitin_P38L,Ubiquitin_38,Uba1,Ubiquitin,P0CG48,1.03226,NO,38,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.718,-2.547,0.829,5.0146,0.316,G,A,,-0.52,,,,OOA,-1.595,0.205827,0.000781418,1.03226 Ubiquitin_Q31D,Ubiquitin_31,Uba1,Ubiquitin,P0CG48,1.03226,NO,31,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-1.678,-2.671,0.993,4.5004,0.464,H,A,,0.68,,,,HPA,-1.44467,0.205827,0.000724141,1.03226 Ubiquitin_Q62I,Ubiquitin_62,Uba1,Ubiquitin,P0CG48,1.03226,NO,62,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-1.836,-2.833,0.997,5.33616,0.762,,B,,0.79,,,,HPB,-1.66167,0.205827,0.00068944,1.03226 beta-lactamase_156_K109F,beta-lactamase_156_109,TEM-1,beta-lactamase_156,P62593,1.03227,NO,109,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.734,-4.437,2.703,,0.787,G,A,2.34,2.21,6.031,,72.73,ABB,-1.63333,0.111618,0.00462493,1.03227 beta-lactamase_39_S201G,beta-lactamase_39_201,TEM-1,beta-lactamase_39,P62593,1.03227,NO,201,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.183,-2.39,1.207,,0.064,H,A,0.27,-0.07,3.54,,64.69,HPB,-1.451,0.0495842,0.00198815,1.03227 PSD95pdz3_S350Q,PSD95pdz3_350,PSD95pdz3,PSD95pdz3,P31016,1.03227,NO,350,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.519,-3.356,1.837,4.97629,,,,,25.01,,,,HPO,-1.29133,0.0758425,0.000704883,1.03227 beta-lactamase_39_I93R,beta-lactamase_39_93,TEM-1,beta-lactamase_39,P62593,1.03228,NO,93,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.401,-4.203,2.802,,0.128,E,B,0.48,0.44,1.757,,67.83,BHB,-1.873,0.0495842,0.00527066,1.03228 beta-lactamase_39_T147V,beta-lactamase_39_147,TEM-1,beta-lactamase_39,P62593,1.03229,NO,147,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.149,-3.22,2.071,,0.281,H,A,0.22,-0.68,13.843,13.843,64.34,HPH,-1.456,0.0495842,0.00226017,1.03229 beta-lactamase_39_G243N,beta-lactamase_39_243,TEM-1,beta-lactamase_39,P62593,1.03232,NO,243,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.0495842,0.00464034,1.03232 beta-lactamase_625_K190W,beta-lactamase_625_190,TEM-1,beta-lactamase_625,P62593,1.03232,NO,190,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.994,-5.522,3.528,,0.371,H,A,2.34,0.16,29.753,29.753,77.62,BBH,-1.64167,0.213352,0.00574527,1.03232 kka2_1:2_R122L,kka2_1:2_122,Kka2,kka2_1:2,P00552,1.03236,NO,122,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.175,-3.603,1.428,,0.487,H,A,1.2,0.26,16.436,16.436,71.59,BBH,-1.53833,0.295029,0.00736512,1.03236 beta-lactamase_39_R159Q,beta-lactamase_39_159,TEM-1,beta-lactamase_39,P62593,1.03238,NO,159,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-0.94,-3.498,2.558,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.0495842,0.00108472,1.03238 kka2_1:1_H8V,kka2_1:1_8,Kka2,kka2_1:1,P00552,1.03239,NO,8,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-2.759,-3.205,0.446,,,,,,,16.971,16.971,71.59,HBH,-2.25467,0.520039,0.00256422,1.03239 beta-lactamase_0_H156I,beta-lactamase_0_156,TEM-1,beta-lactamase_0,P62593,1.03241,NO,156,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-3.156,-4.08,0.924,,0.753,S,A,0.17,-0.6,23.367,23.367,77.62,ABH,-1.932,0.0500837,0.00468596,1.03241 Pab1_D144S,Pab1_144,Pab1,Pab1,P04147,1.03241,NO,144,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.189,-3.053,1.864,,0.616,H,A,,0.6,,,,HAP,-1.40567,0.175299,0.00121131,1.03241 kka2_1:4_A247V,kka2_1:4_247,Kka2,kka2_1:4,P00552,1.03243,NO,247,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.459,-2.971,0.512,,1.01,S,A,0.46,0.65,,,92.05,HHH,-2.197,0.168804,0.0102428,1.03243 PSD95pdz3_T385P,PSD95pdz3_385,PSD95pdz3,PSD95pdz3,P31016,1.03244,NO,385,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.533,-3.432,1.899,5.57157,,,,,23.6871,4.527,,87.71,PPH,-1.56567,0.0758425,0.000545119,1.03244 beta-lactamase_625_R118Q,beta-lactamase_625_118,TEM-1,beta-lactamase_625,P62593,1.03245,NO,118,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.413,-3.932,1.519,,0.457,H,A,1.2,1.39,2.144,,77.62,HBA,-1.785,0.213352,0.00538794,1.03245 beta-lactamase_0_A222D,beta-lactamase_0_222,TEM-1,beta-lactamase_0,P62593,1.03247,NO,222,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.103,-3.723,1.62,,0.233,H,A,0.46,-0.25,2.015,,77.62,PHH,-1.63733,0.0500837,0.00466094,1.03247 WW_domain_F189Y,WW_domain_189,Yap65,WW_domain,P46937,1.03251,NO,189,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.632,-2.266,0.634,5.47284,,,,,,6.165,,56.94,HHH,-1.454,0.153962,0.00308453,1.03251 beta-lactamase_39_D174E,beta-lactamase_39_174,TEM-1,beta-lactamase_39,P62593,1.03253,NO,174,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.738,-2.765,2.027,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.0495842,0.00125633,1.03253 beta-lactamase_625_L73C,beta-lactamase_625_73,TEM-1,beta-lactamase_625,P62593,1.03253,NO,73,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.507,-4.861,3.354,,,H,A,0.55,-0.64,2.933,,67.83,HHH,-1.487,0.213352,0.00488983,1.03253 PSD95pdz3_A343S,PSD95pdz3_343,PSD95pdz3,PSD95pdz3,P31016,1.03253,NO,343,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.307,-2.617,1.31,5.585,,,,,14.728,,,,HHO,-1.22067,0.0758425,0.000798084,1.03253 beta-lactamase_Q97E,beta-lactamase_97,TEM-1,beta-lactamase,P62593,1.03254,NO,97,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.072,-2.167,0.095,6.30204,0.823,G,A,1.1,2.42,1.157,,77.62,PPP,-2.43833,0.221079,0.0045116,1.03254 beta-lactamase_T138Q,beta-lactamase_138,TEM-1,beta-lactamase,P62593,1.03254,NO,138,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.506,-3.82,1.314,5.52585,0.662,H,A,0.3,-0.03,30.445,30.445,73.78,HPP,-1.81233,0.221079,0.00487868,1.03254 beta-lactamase_39_E26K,beta-lactamase_39_26,TEM-1,beta-lactamase_39,P62593,1.03256,NO,26,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.454,-3.374,0.92,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.0495842,0.00297948,1.03256 kka2_1:8_L102I,kka2_1:8_102,Kka2,kka2_1:8,P00552,1.03257,NO,102,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.804,-2.957,2.153,,,T,A,1.59,-1.17,0.97,,42.42,AHH,-1.398,0.100394,0.00201332,1.03257 kka2_1:8_L102I,kka2_1:8_102,Kka2,kka2_1:8,P00552,1.03257,NO,102,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.804,-2.957,2.153,,,T,A,1.59,-1.17,0.97,,42.42,AHH,-1.398,0.100394,0.00201332,1.03257 beta-lactamase_156_I285H,beta-lactamase_156_285,TEM-1,beta-lactamase_156,P62593,1.03261,NO,285,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.845,-3.788,1.943,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.111618,0.101555,1.03261 beta-lactamase_39_P65V,beta-lactamase_39_65,TEM-1,beta-lactamase_39,P62593,1.03261,NO,65,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.894,-3.39,2.496,,0.098,E,B,0.52,-0.62,0.623,,40.56,HOH,-1.03233,0.0495842,0.00152776,1.03261 beta-lactamase_0_E195S,beta-lactamase_0_195,TEM-1,beta-lactamase_0,P62593,1.03263,NO,195,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.186,-2.512,0.326,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.0500837,0.00496565,1.03263 beta-lactamase_39_H110P,beta-lactamase_39_110,TEM-1,beta-lactamase_39,P62593,1.03263,NO,110,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-1.706,-2.996,1.29,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.0495842,0.00441499,1.03263 kka2_1:8_E182F,kka2_1:8_182,Kka2,kka2_1:8,P00552,1.03266,NO,182,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.516,-4.259,2.743,,0.326,,B,1.52,0.75,2.568,,65.53,OAA,-1.806,0.100394,0.00641548,1.03266 kka2_1:8_E182F,kka2_1:8_182,Kka2,kka2_1:8,P00552,1.03266,NO,182,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.516,-4.259,2.743,,0.326,,B,1.52,0.75,2.568,,65.53,OAA,-1.806,0.100394,0.00641548,1.03266 beta-lactamase_625_F70I,beta-lactamase_625_70,TEM-1,beta-lactamase_625,P62593,1.03267,NO,70,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.169,-3.353,2.184,,,H,A,0.58,-1.34,1.14,,63.99,PHB,-0.980667,0.213352,0.00193499,1.03267 beta-lactamase_0_D231Q,beta-lactamase_0_231,TEM-1,beta-lactamase_0,P62593,1.03269,NO,231,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.816,-3.637,2.821,,,E,B,0.75,-1.06,4.975,,65.38,HAB,-0.994,0.0500837,0.00107395,1.03269 PSD95pdz3_D366P,PSD95pdz3_366,PSD95pdz3,PSD95pdz3,P31016,1.03269,NO,366,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.264,-3.336,2.072,5.55684,,,,,20.2375,,,,HAH,-1.401,0.0758425,0.000481272,1.03269 E1_Ubiquitin_G47D,E1_Ubiquitin_47,Uba1,E1_Ubiquitin,P0CG63,1.03271,NO,47,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.999,-3.279,2.28,,0.057,T,l,,-1.21,,,,HOB,-1.195,0.18783,0.00142261,1.03271 E1_Ubiquitin_G47R,E1_Ubiquitin_47,Uba1,E1_Ubiquitin,P0CG63,1.03271,NO,47,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.999,-3.592,2.593,,0.057,T,l,,-1.21,,,,HOB,-1.195,0.18783,0.00142261,1.03271 E1_Ubiquitin_Q41A,E1_Ubiquitin_41,Uba1,E1_Ubiquitin,P0CG63,1.03271,NO,41,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-1.25,-2.895,1.645,,0.017,E,B,,-0.98,,,,PPB,-1.344,0.18783,0.00215097,1.03271 beta-lactamase_2500_R118Q,beta-lactamase_2500_118,TEM-1,beta-lactamase_2500,P62593,1.03274,NO,118,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.413,-3.932,1.519,,0.457,H,A,1.2,1.39,2.144,,77.62,HBA,-1.785,0.361275,0.00538794,1.03274 beta-lactamase_625_F58W,beta-lactamase_625_58,TEM-1,beta-lactamase_625,P62593,1.03276,NO,58,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-2.914,-2.275,-0.639,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.213352,0.00523369,1.03276 kka2_1:4_K138N,kka2_1:4_138,Kka2,kka2_1:4,P00552,1.03276,NO,138,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-2.5,-3.757,1.257,,0.594,H,A,1.3,0.98,21.267,21.267,71.59,HBB,-2.48833,0.168804,0.00628542,1.03276 beta-lactamase_2500_K190Y,beta-lactamase_2500_190,TEM-1,beta-lactamase_2500,P62593,1.03277,NO,190,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.994,-4.283,2.289,,0.371,H,A,2.34,0.16,29.753,29.753,77.62,BBH,-1.64167,0.361275,0.00574527,1.03277 beta-lactamase_625_T138C,beta-lactamase_625_138,TEM-1,beta-lactamase_625,P62593,1.03277,NO,138,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.506,-5.125,2.619,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.213352,0.00487868,1.03277 beta-lactamase_0_E102A,beta-lactamase_0_102,TEM-1,beta-lactamase_0,P62593,1.03279,NO,102,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.118,-2.327,0.209,,0.722,S,B,1.04,1.82,4.773,,73.08,HAH,-1.581,0.0500837,0.00486633,1.03279 gb1_Q228H,gb1_228,gb1,gb1,P06654,1.03279,NO,228,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,,,,,,,,,,,,,OPH,-1.282,0.177985,0.00391043,1.03279 PSD95pdz3_P346C,PSD95pdz3_346,PSD95pdz3,PSD95pdz3,P31016,1.0328,NO,346,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.236,-4.769,3.533,5.02406,,,,,14.6629,,,,OOH,-1.18367,0.0758425,0.000758563,1.0328 beta-lactamase_39_A84Q,beta-lactamase_39_84,TEM-1,beta-lactamase_39,P62593,1.03282,NO,84,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.651,-2.658,1.007,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.0495842,0.00503822,1.03282 beta-lactamase_39_F58L,beta-lactamase_39_58,TEM-1,beta-lactamase_39,P62593,1.03282,NO,58,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-2.914,-3.474,0.56,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.0495842,0.00523369,1.03282 beta-lactamase_V8F,beta-lactamase_8,TEM-1,beta-lactamase,P62593,1.03282,NO,8,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-2.358,-3.819,1.461,,,,,,,0.575,,77.62,BHH,-2.06267,0.221079,0.00226401,1.03282 PSD95pdz3_V365W,PSD95pdz3_365,PSD95pdz3,PSD95pdz3,P31016,1.03283,NO,365,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.592,-5.099,3.507,5.03791,,,,,18.9657,2.364,,81.35,OHA,-1.288,0.0758425,0.000649764,1.03283 beta-lactamase_0_T198E,beta-lactamase_0_198,TEM-1,beta-lactamase_0,P62593,1.03285,NO,198,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.168,-3.379,1.211,,0.489,,B,0.22,-0.13,9.874,,73.78,HPH,-1.98767,0.0500837,0.004311,1.03285 beta-lactamase_156_L192F,beta-lactamase_156_192,TEM-1,beta-lactamase_156,P62593,1.03285,NO,192,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.254,-2.572,1.318,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.111618,0.00558728,1.03285 PSD95pdz3_G364N,PSD95pdz3_364,PSD95pdz3,PSD95pdz3,P31016,1.03287,NO,364,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.008,-3.13,2.122,5.53299,,,,,21.28,,,,POH,-1.33667,0.0758425,0.00050942,1.03287 beta-lactamase_0_L49A,beta-lactamase_0_49,TEM-1,beta-lactamase_0,P62593,1.03288,NO,49,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.897,-3.125,1.228,,0.131,T,A,0.55,0.04,13.838,13.838,64.69,AHP,-1.99233,0.0500837,0.00401477,1.03288 beta-lactamase_39_F228H,beta-lactamase_39_228,TEM-1,beta-lactamase_39,P62593,1.03288,NO,228,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-2.342,-3.331,0.989,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.0495842,0.0046669,1.03288 WW_domain_D170Y,WW_domain_170,Yap65,WW_domain,P46937,1.03289,NO,170,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.213,-4.158,2.945,,,,,,,0.399,,15.87,OAH,-1.38,0.153962,0.00123319,1.03289 beta-lactamase_2500_E272D,beta-lactamase_2500_272,TEM-1,beta-lactamase_2500,P62593,1.0329,NO,272,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.361275,0.00545371,1.0329 PSD95pdz3_S320Q,PSD95pdz3_320,PSD95pdz3,PSD95pdz3,P31016,1.03291,NO,320,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.519,-3.356,1.837,5.81757,,,,,21.4517,,,,OPP,-1.306,0.0758425,0.00108158,1.03291 kka2_1:8_T225S,kka2_1:8_225,Kka2,kka2_1:8,P00552,1.03292,NO,225,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.393,-2.531,0.138,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.100394,0.0113598,1.03292 kka2_1:8_T225S,kka2_1:8_225,Kka2,kka2_1:8,P00552,1.03292,NO,225,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.393,-2.531,0.138,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.100394,0.0113598,1.03292 PSD95pdz3_S361Q,PSD95pdz3_361,PSD95pdz3,PSD95pdz3,P31016,1.03292,NO,361,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.519,-3.356,1.837,4.8722,,,,,16.4533,,,,HPH,-1.47167,0.0758425,0.00055296,1.03292 beta-lactamase_39_G240H,beta-lactamase_39_240,TEM-1,beta-lactamase_39,P62593,1.03293,NO,240,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.0495842,0.00591201,1.03293 kka2_1:2_L212M,kka2_1:2_212,Kka2,kka2_1:2,P00552,1.03296,NO,212,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.904,-3.974,3.07,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.295029,0.0031426,1.03296 beta-lactamase_39_S241E,beta-lactamase_39_241,TEM-1,beta-lactamase_39,P62593,1.03297,NO,241,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.0495842,0.00452736,1.03297 PSD95pdz3_V386S,PSD95pdz3_386,PSD95pdz3,PSD95pdz3,P31016,1.03298,NO,386,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.465,-3.292,1.827,5.18836,,,,,17.5429,,,,PHP,-1.463,0.0758425,0.000184509,1.03298 beta-lactamase_625_G253K,beta-lactamase_625_253,TEM-1,beta-lactamase_625,P62593,1.033,NO,253,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.213352,0.00786358,1.033 kka2_1:4_T73N,kka2_1:4_73,Kka2,kka2_1:4,P00552,1.033,NO,73,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.51,-3.876,1.366,,0.309,H,A,0.22,0.35,1.53,,56.06,PPO,-2.02333,0.168804,0.00628605,1.033 beta-lactamase_156_A170C,beta-lactamase_156_170,TEM-1,beta-lactamase_156,P62593,1.03301,NO,170,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.237,-4.736,3.499,,0.126,,L,0.46,-0.35,3.7,,64.69,AHH,-1.63267,0.111618,0.00431903,1.03301 beta-lactamase_156_A222F,beta-lactamase_156_222,TEM-1,beta-lactamase_156,P62593,1.03301,NO,222,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.103,-4.23,2.127,,0.233,H,A,0.46,-0.25,2.461,,77.62,PHH,-1.63733,0.111618,0.00466094,1.03301 beta-lactamase_39_F228Y,beta-lactamase_39_228,TEM-1,beta-lactamase_39,P62593,1.03302,NO,228,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-2.342,-4.005,1.663,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.0495842,0.0046669,1.03302 beta-lactamase_156_D271N,beta-lactamase_156_271,TEM-1,beta-lactamase_156,P62593,1.03303,NO,271,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.111618,0.00752082,1.03303 beta-lactamase_39_H110Q,beta-lactamase_39_110,TEM-1,beta-lactamase_39,P62593,1.03303,NO,110,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-1.706,-2.734,1.028,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.0495842,0.00441499,1.03303 kka2_1:8_P76S,kka2_1:8_76,Kka2,kka2_1:8,P00552,1.03303,NO,76,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.449,-2.672,1.223,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.100394,0.00625685,1.03303 kka2_1:8_P76S,kka2_1:8_76,Kka2,kka2_1:8,P00552,1.03303,NO,76,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.449,-2.672,1.223,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.100394,0.00625685,1.03303 kka2_1:2_R202C,kka2_1:2_202,Kka2,kka2_1:2,P00552,1.03306,NO,202,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.761,-3.597,1.836,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.295029,0.00696498,1.03306 PSD95pdz3_Q374F,PSD95pdz3_374,PSD95pdz3,PSD95pdz3,P31016,1.03306,NO,374,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-1.699,-3.974,2.275,5.38825,,,,,17.3289,,,,APH,-1.47,0.0758425,0.000372298,1.03306 beta-lactamase_39_E108A,beta-lactamase_39_108,TEM-1,beta-lactamase_39,P62593,1.03307,NO,108,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.46,-2.613,1.153,,0.572,G,A,1.04,1.87,20.151,20.151,72.73,PAB,-1.437,0.0495842,0.00413372,1.03307 beta-lactamase_T138R,beta-lactamase_138,TEM-1,beta-lactamase,P62593,1.03307,NO,138,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.506,-2.605,0.099,5.52585,0.662,H,A,0.3,-0.03,30.445,30.445,73.78,HPP,-1.81233,0.221079,0.00487868,1.03307 kka2_1:2_N58K,kka2_1:2_58,Kka2,kka2_1:2,P00552,1.03307,NO,58,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-2.641,-3.669,1.028,,0.131,S,A,0.43,0.72,5.729,,71.59,HPA,-1.83033,0.295029,0.00793425,1.03307 PSD95pdz3_A382S,PSD95pdz3_382,PSD95pdz3,PSD95pdz3,P31016,1.03308,NO,382,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.307,-2.617,1.31,5.30282,,,,,22.472,,,,PHO,-1.24167,0.0758425,0.000249256,1.03308 beta-lactamase_625_F58L,beta-lactamase_625_58,TEM-1,beta-lactamase_625,P62593,1.03309,NO,58,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-2.914,-3.474,0.56,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.213352,0.00523369,1.03309 beta-lactamase_625_L150M,beta-lactamase_625_150,TEM-1,beta-lactamase_625,P62593,1.03309,NO,150,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.326,-2.392,1.066,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.213352,0.00463171,1.03309 kka2_1:8_A229I,kka2_1:8_229,Kka2,kka2_1:8,P00552,1.03309,NO,229,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.739,-3.861,2.122,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.100394,0.00942138,1.03309 kka2_1:8_A229I,kka2_1:8_229,Kka2,kka2_1:8,P00552,1.03309,NO,229,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.739,-3.861,2.122,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.100394,0.00942138,1.03309 beta-lactamase_625_E26L,beta-lactamase_625_26,TEM-1,beta-lactamase_625,P62593,1.03311,NO,26,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.454,-2.726,0.272,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.213352,0.00297948,1.03311 PSD95pdz3_S361K,PSD95pdz3_361,PSD95pdz3,PSD95pdz3,P31016,1.03311,NO,361,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.519,-2.914,1.395,4.8722,,,,,16.4533,,,,HPH,-1.47167,0.0758425,0.00055296,1.03311 beta-lactamase_A200N,beta-lactamase_200,TEM-1,beta-lactamase,P62593,1.03312,NO,200,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.878,-3.758,1.88,5.19406,0.757,H,A,0.47,-0.19,0.436,,77.62,HHP,-2.001,0.221079,0.0060056,1.03312 kka2_1:8_G6V,kka2_1:8_6,Kka2,kka2_1:8,P00552,1.03312,NO,6,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.685,-3.428,1.743,,,,,,,,,71.59,AOH,-1.639,0.100394,0.00204693,1.03312 kka2_1:8_G6V,kka2_1:8_6,Kka2,kka2_1:8,P00552,1.03312,NO,6,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.685,-3.428,1.743,,,,,,,,,71.59,AOH,-1.639,0.100394,0.00204693,1.03312 PSD95pdz3_S339A,PSD95pdz3_339,PSD95pdz3,PSD95pdz3,P31016,1.03312,NO,339,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.519,-2.309,0.79,5.34493,,,,,12.2167,,,,HPH,-1.55767,0.0758425,0.00084982,1.03312 beta-lactamase_39_A282R,beta-lactamase_39_282,TEM-1,beta-lactamase_39,P62593,1.03313,NO,282,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.0495842,0.0449821,1.03313 beta-lactamase_39_E195H,beta-lactamase_39_195,TEM-1,beta-lactamase_39,P62593,1.03313,NO,195,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.186,-3.381,1.195,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.0495842,0.00496565,1.03313 beta-lactamase_625_I245T,beta-lactamase_625_245,TEM-1,beta-lactamase_625,P62593,1.03314,NO,245,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.213352,0.00391032,1.03314 kka2_1:2_D134P,kka2_1:2_134,Kka2,kka2_1:2,P00552,1.03315,NO,134,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.969,-3.811,2.842,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.295029,0.00270812,1.03315 beta-lactamase_156_E279I,beta-lactamase_156_279,TEM-1,beta-lactamase_156,P62593,1.03316,NO,279,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.111618,0.0192826,1.03316 beta-lactamase_0_K71N,beta-lactamase_0_71,TEM-1,beta-lactamase_0,P62593,1.03318,NO,71,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-0.8,-3.448,2.648,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.0500837,0.00103192,1.03318 beta-lactamase_625_E46F,beta-lactamase_625_46,TEM-1,beta-lactamase_625,P62593,1.03318,NO,46,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.94,-4.056,2.116,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.213352,0.00427568,1.03318 gb1_T243A,gb1_243,gb1,gb1,P06654,1.03318,NO,243,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.415,-1.795,0.38,,,,,,,1.083,,37.28,PPP,-1.43233,0.177985,0.00308687,1.03318 beta-lactamase_0_R220H,beta-lactamase_0_220,TEM-1,beta-lactamase_0,P62593,1.03319,NO,220,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-0.942,-4.298,3.356,,0.295,I,A,1.2,-0.76,21.573,21.573,74.48,HBP,-1.33633,0.0500837,0.00232421,1.03319 beta-lactamase_N50D,beta-lactamase_50,TEM-1,beta-lactamase,P62593,1.0332,NO,50,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-2.979,-2.468,-0.511,5.51261,0.912,T,A,1.07,1.24,1.581,,77.62,HPP,-2.134,0.221079,0.0047211,1.0332 beta-lactamase_E237P,beta-lactamase_237,TEM-1,beta-lactamase,P62593,1.03324,NO,237,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.058,-3.985,1.927,5.42877,0.583,S,B,1.62,1.2,2.144,,77.62,OAB,-1.61467,0.221079,0.0048626,1.03324 Pab1_D151Q,Pab1_151,Pab1,Pab1,P04147,1.03325,NO,151,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.399,-3.555,1.156,,,,,,,,,,OAH,-1.51767,0.175299,0.00228155,1.03325 beta-lactamase_39_S233T,beta-lactamase_39_233,TEM-1,beta-lactamase_39,P62593,1.03327,NO,233,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.886,-1.229,-0.657,,0.016,E,B,0.27,-1.01,5.361,,77.62,BPO,-1.17267,0.0495842,0.00311415,1.03327 beta-lactamase_0_D155M,beta-lactamase_0_155,TEM-1,beta-lactamase_0,P62593,1.0333,NO,155,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.889,-4.929,4.04,,0.049,,B,0.75,-0.9,16.833,16.833,64.69,OAB,-1.62267,0.0500837,0.00135315,1.0333 beta-lactamase_156_F228N,beta-lactamase_156_228,TEM-1,beta-lactamase_156,P62593,1.0333,NO,228,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-2.342,-3.038,0.696,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.111618,0.0046669,1.0333 beta-lactamase_156_T131V,beta-lactamase_156_131,TEM-1,beta-lactamase_156,P62593,1.0333,NO,131,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.328,-3.345,2.017,,,H,A,0.22,-0.69,2.031,,67.48,PPH,-1.00867,0.111618,0.00345886,1.0333 beta-lactamase_39_R63Q,beta-lactamase_39_63,TEM-1,beta-lactamase_39,P62593,1.0333,NO,63,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-0.943,-3.532,2.589,,0.218,,B,1.2,-0.31,0.326,,44.06,ABH,-0.992333,0.0495842,0.00126938,1.0333 PSD95pdz3_G319R,PSD95pdz3_319,PSD95pdz3,PSD95pdz3,P31016,1.0333,NO,319,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.008,-3.615,2.607,4.95387,,,,,18.8725,,,,BOP,-1.36967,0.0758425,0.00109317,1.0333 beta-lactamase_0_R242P,beta-lactamase_0_242,TEM-1,beta-lactamase_0,P62593,1.03331,NO,242,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.0500837,0.00452879,1.03331 beta-lactamase_39_R63T,beta-lactamase_39_63,TEM-1,beta-lactamase_39,P62593,1.03331,NO,63,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-0.943,-3.447,2.504,,0.218,,B,1.2,-0.31,0.326,,44.06,ABH,-0.992333,0.0495842,0.00126938,1.03331 gb1_D272A,gb1_272,gb1,gb1,P06654,1.03331,NO,272,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.457,-3.107,1.65,,,,,,,0.234,,11.83,HAA,-1.54533,0.177985,0.00218257,1.03331 PSD95pdz3_D332N,PSD95pdz3_332,PSD95pdz3,PSD95pdz3,P31016,1.03331,NO,332,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.264,-2.905,1.641,6.09878,,,,,48.762,,,,AAO,-1.22533,0.0758425,0.000937818,1.03331 beta-lactamase_39_L248Y,beta-lactamase_39_248,TEM-1,beta-lactamase_39,P62593,1.03332,NO,248,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.0495842,0.00428493,1.03332 beta-lactamase_T139E,beta-lactamase_139,TEM-1,beta-lactamase,P62593,1.03333,NO,139,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.901,-2.44,0.539,5.69095,0.216,H,A,0.3,0.39,2.256,,77.62,PPH,-2.04667,0.221079,0.00441837,1.03333 beta-lactamase_39_E46M,beta-lactamase_39_46,TEM-1,beta-lactamase_39,P62593,1.0334,NO,46,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.94,-4.375,2.435,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.0495842,0.00427568,1.0334 PSD95pdz3_T387V,PSD95pdz3_387,PSD95pdz3,PSD95pdz3,P31016,1.0334,NO,387,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.391,-2.76,1.369,5.20757,,,,,18.8043,,,,HPH,-1.49533,0.0758425,0.000167911,1.0334 beta-lactamase_156_H110E,beta-lactamase_156_110,TEM-1,beta-lactamase_156,P62593,1.03342,NO,110,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-1.706,-2.766,1.06,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.111618,0.00441499,1.03342 kka2_1:2_L81V,kka2_1:2_81,Kka2,kka2_1:2,P00552,1.03342,NO,81,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.427,-1.839,0.412,,0.46,E,A,1.59,-0.14,1.895,,63.64,HHA,-1.50567,0.295029,0.00805839,1.03342 beta-lactamase_A200H,beta-lactamase_200,TEM-1,beta-lactamase,P62593,1.03343,NO,200,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.878,-4.732,2.854,5.19406,0.757,H,A,0.47,-0.19,0.436,,77.62,HHP,-2.001,0.221079,0.0060056,1.03343 kka2_1:4_E86F,kka2_1:4_86,Kka2,kka2_1:4,P00552,1.03343,NO,86,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.86,-4.247,2.387,,0.369,.,B,1.04,1.92,4.451,,63.26,PAH,-1.98067,0.168804,0.00642858,1.03343 kka2_1:4_A71C,kka2_1:4_71,Kka2,kka2_1:4,P00552,1.03344,NO,71,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.824,-5.109,3.285,,0.553,H,A,0.46,0.08,5.76,,64.39,HHP,-1.74033,0.168804,0.00727707,1.03344 beta-lactamase_39_E87G,beta-lactamase_39_87,TEM-1,beta-lactamase_39,P62593,1.03345,NO,87,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.421,-3.541,2.12,,0.048,,B,1.04,0.92,15.231,15.231,64.69,PAP,-1.969,0.0495842,0.00337888,1.03345 kka2_1:8_S40R,kka2_1:8_40,Kka2,kka2_1:8,P00552,1.03346,NO,40,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.645,-2.494,-0.151,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.100394,0.00693477,1.03346 kka2_1:8_S40R,kka2_1:8_40,Kka2,kka2_1:8,P00552,1.03346,NO,40,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.645,-2.494,-0.151,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.100394,0.00693477,1.03346 beta-lactamase_156_I171T,beta-lactamase_156_171,TEM-1,beta-lactamase_156,P62593,1.03349,NO,171,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-2.431,-2.05,-0.381,,0.361,,B,0.48,0.53,3.869,,77.62,HHO,-1.55533,0.111618,0.00623355,1.03349 beta-lactamase_625_K190T,beta-lactamase_625_190,TEM-1,beta-lactamase_625,P62593,1.03349,NO,190,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.994,-2.389,0.395,,0.371,H,A,2.34,0.16,29.753,29.753,77.62,BBH,-1.64167,0.213352,0.00574527,1.03349 PSD95pdz3_A378H,PSD95pdz3_378,PSD95pdz3,PSD95pdz3,P31016,1.0335,NO,378,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.307,-4.362,3.055,4.86582,,,,,14.576,,,,HHH,-1.509,0.0758425,0.000313169,1.0335 beta-lactamase_625_R275D,beta-lactamase_625_275,TEM-1,beta-lactamase_625,P62593,1.03352,NO,275,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.213352,0.0141984,1.03352 beta-lactamase_0_A183T,beta-lactamase_0_183,TEM-1,beta-lactamase_0,P62593,1.03353,NO,183,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.231,-3.281,2.05,,0.155,H,A,0.46,-0.91,1.48,,77.62,HHH,-1.53367,0.0500837,0.00296631,1.03353 beta-lactamase_0_P217S,beta-lactamase_0_217,TEM-1,beta-lactamase_0,P62593,1.03353,NO,217,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-2.062,-2.615,0.553,,0.496,I,A,0.52,-0.33,1.087,,74.48,OOH,-1.64333,0.0500837,0.00463211,1.03353 beta-lactamase_156_E26Y,beta-lactamase_156_26,TEM-1,beta-lactamase_156,P62593,1.03355,NO,26,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.454,-4.272,1.818,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.111618,0.00297948,1.03355 kka2_1:2_Q136I,kka2_1:2_136,Kka2,kka2_1:2,P00552,1.03355,NO,136,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-3.021,-4.106,1.085,,0.331,,b,0.4,0.96,2.726,,92.05,BPH,-2.16933,0.295029,0.00624149,1.03355 kka2_1:8_S114I,kka2_1:8_114,Kka2,kka2_1:8,P00552,1.03355,NO,114,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.527,-3.933,1.406,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.100394,0.00705262,1.03355 kka2_1:8_S114I,kka2_1:8_114,Kka2,kka2_1:8,P00552,1.03355,NO,114,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.527,-3.933,1.406,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.100394,0.00705262,1.03355 beta-lactamase_625_V106I,beta-lactamase_625_106,TEM-1,beta-lactamase_625,P62593,1.03356,NO,106,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.218,-2.124,0.906,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.213352,0.00304168,1.03356 gb1_T251K,gb1_251,gb1,gb1,P06654,1.03357,NO,251,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.794,-3.172,1.378,,,,,,,3.514,3.514,37.28,HPH,-1.56067,0.177985,0.00232932,1.03357 gb1_T277D,gb1_277,gb1,gb1,P06654,1.03357,NO,277,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.771,-2.297,0.526,,,,,,,0.824,,35.71,BPH,-1.54833,0.177985,0.00348258,1.03357 kka2_1:2_L174C,kka2_1:2_174,Kka2,kka2_1:2,P00552,1.03357,NO,174,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.952,-4.719,3.767,,,H,A,1.59,-0.31,8.521,,51.89,BHB,-2.08533,0.295029,0.00438501,1.03357 kka2_1:8_A87V,kka2_1:8_87,Kka2,kka2_1:8,P00552,1.03358,NO,87,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.917,-3.732,1.815,,1.039,S,L,0.46,1.57,16.115,16.115,65.53,AHO,-1.822,0.100394,0.00791281,1.03358 kka2_1:8_A87V,kka2_1:8_87,Kka2,kka2_1:8,P00552,1.03358,NO,87,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.917,-3.732,1.815,,1.039,S,L,0.46,1.57,16.115,16.115,65.53,AHO,-1.822,0.100394,0.00791281,1.03358 kka2_1:8_G88D,kka2_1:8_88,Kka2,kka2_1:8,P00552,1.03362,NO,88,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.689,-2.184,0.495,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.100394,0.00685559,1.03362 kka2_1:8_G88D,kka2_1:8_88,Kka2,kka2_1:8,P00552,1.03362,NO,88,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.689,-2.184,0.495,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.100394,0.00685559,1.03362 kka2_1:8_M1L,kka2_1:8_1,Kka2,kka2_1:8,P00552,1.03362,NO,1,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.787,-2.339,0.552,,,,,,,16.725,16.725,62.12,NAHH,-1.787,0.100394,0.00251939,1.03362 kka2_1:8_M1L,kka2_1:8_1,Kka2,kka2_1:8,P00552,1.03362,NO,1,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.787,-2.339,0.552,,,,,,,16.725,16.725,62.12,NAHH,-1.787,0.100394,0.00251939,1.03362 PSD95pdz3_K355A,PSD95pdz3_355,PSD95pdz3,PSD95pdz3,P31016,1.03365,NO,355,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.416,-2.759,1.343,5.56865,,,,,17.2556,,,,BBO,-1.33533,0.0758425,0.00063703,1.03365 PSD95pdz3_K355I,PSD95pdz3_355,PSD95pdz3,PSD95pdz3,P31016,1.03366,NO,355,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.416,-3.692,2.276,5.56865,,,,,17.2556,,,,BBO,-1.33533,0.0758425,0.00063703,1.03366 PSD95pdz3_A343H,PSD95pdz3_343,PSD95pdz3,PSD95pdz3,P31016,1.03367,NO,343,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.307,-4.362,3.055,5.585,,,,,14.728,,,,HHO,-1.22067,0.0758425,0.000798084,1.03367 kka2_1:1_D5T,kka2_1:1_5,Kka2,kka2_1:1,P00552,1.03368,NO,5,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.306,-3.232,1.926,,,,,,,0.895,,71.59,PAO,-1.784,0.520039,0.00222864,1.03368 WW_domain_D194F,WW_domain_194,Yap65,WW_domain,P46937,1.03369,NO,194,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.536,-4.089,2.553,5.95614,,,,,,1.948,,74.4,HAP,-1.78933,0.153962,0.00483742,1.03369 beta-lactamase_156_A34F,beta-lactamase_156_34,TEM-1,beta-lactamase_156,P62593,1.0337,NO,34,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.059,-3.937,1.878,,,H,A,0.46,-0.54,3.614,,73.78,AHA,-1.74967,0.111618,0.00407913,1.0337 gb1_T270K,gb1_270,gb1,gb1,P06654,1.0337,NO,270,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-3.15,-3.338,0.188,,,,,,,1.326,,45.54,HPH,-1.843,0.177985,0.00223707,1.0337 beta-lactamase_2500_K190H,beta-lactamase_2500_190,TEM-1,beta-lactamase_2500,P62593,1.03371,NO,190,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.994,-3.068,1.074,,0.371,H,A,2.34,0.16,29.753,29.753,77.62,BBH,-1.64167,0.361275,0.00574527,1.03371 beta-lactamase_39_D212K,beta-lactamase_39_212,TEM-1,beta-lactamase_39,P62593,1.03371,NO,212,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.624,-3.581,1.957,,0.037,,b,0.75,-0.58,10.748,10.748,74.48,HAB,-1.77667,0.0495842,0.00644302,1.03371 kka2_1:2_G181V,kka2_1:2_181,Kka2,kka2_1:2,P00552,1.03371,NO,181,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-2.698,-2.527,-0.171,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.295029,0.00728319,1.03371 Pab1_G126W,Pab1_126,Pab1,Pab1,P04147,1.03371,NO,126,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.985,-5.018,4.033,,0.011,T,A,0.46,-0.07,2.349,,80.42,OOP,-1.032,0.175299,0.00109814,1.03371 beta-lactamase_156_E26H,beta-lactamase_156_26,TEM-1,beta-lactamase_156,P62593,1.03375,NO,26,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.454,-4.609,2.155,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.111618,0.00297948,1.03375 beta-lactamase_39_E26N,beta-lactamase_39_26,TEM-1,beta-lactamase_39,P62593,1.03375,NO,26,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.454,-3.711,1.257,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.0495842,0.00297948,1.03375 beta-lactamase_39_P60F,beta-lactamase_39_60,TEM-1,beta-lactamase_39,P62593,1.03375,NO,60,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-2.469,-4.292,1.823,,0.256,T,A,0.52,-0.56,21.37,21.37,77.62,BOA,-1.97633,0.0495842,0.00521318,1.03375 beta-lactamase_Q265S,beta-lactamase_265,TEM-1,beta-lactamase,P62593,1.03376,NO,265,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.58,-2.704,0.124,6.62674,1.116,,A,0.03,1.17,12.514,12.514,69.58,PPH,-1.978,0.221079,0.00811926,1.03376 beta-lactamase_39_T186C,beta-lactamase_39_186,TEM-1,beta-lactamase_39,P62593,1.0338,NO,186,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.522,-5.021,2.499,,0.396,H,A,0.22,-0.28,0.515,,77.62,HPP,-1.77633,0.0495842,0.00485034,1.0338 beta-lactamase_625_E61F,beta-lactamase_625_61,TEM-1,beta-lactamase_625,P62593,1.0338,NO,61,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.115,-4.422,2.307,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.213352,0.00440955,1.0338 kka2_1:4_V214L,kka2_1:4_214,Kka2,kka2_1:4,P00552,1.03383,NO,214,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.261,-2.012,0.751,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.168804,0.00692782,1.03383 kka2_1:8_L94Q,kka2_1:8_94,Kka2,kka2_1:8,P00552,1.03383,NO,94,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.618,-4.05,2.432,,0.058,E,B,1.59,-0.52,2.197,,56.06,HHO,-1.612,0.100394,0.00520888,1.03383 kka2_1:8_L94Q,kka2_1:8_94,Kka2,kka2_1:8,P00552,1.03383,NO,94,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.618,-4.05,2.432,,0.058,E,B,1.59,-0.52,2.197,,56.06,HHO,-1.612,0.100394,0.00520888,1.03383 kka2_1:8_Q61F,kka2_1:8_61,Kka2,kka2_1:8,P00552,1.03384,NO,61,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.982,-4.457,1.475,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.100394,0.00612092,1.03384 kka2_1:8_Q61F,kka2_1:8_61,Kka2,kka2_1:8,P00552,1.03384,NO,61,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.982,-4.457,1.475,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.100394,0.00612092,1.03384 beta-lactamase_0_N173G,beta-lactamase_0_173,TEM-1,beta-lactamase_0,P62593,1.03385,NO,173,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-2.663,-1.002,-1.661,,1.044,T,l,0.61,1.25,1.133,,77.62,OPA,-1.46633,0.0500837,0.0033769,1.03385 beta-lactamase_625_Q88W,beta-lactamase_625_88,TEM-1,beta-lactamase_625,P62593,1.03385,NO,88,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.086,-5.502,3.416,,0.807,,B,0.64,2.03,1.84,,77.62,APH,-1.53433,0.213352,0.00504167,1.03385 beta-lactamase_39_L223T,beta-lactamase_39_223,TEM-1,beta-lactamase_39,P62593,1.03386,NO,223,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.055,-2.595,1.54,,0.27,,B,0.55,0.09,1.511,,74.48,HHO,-1.35033,0.0495842,0.00372793,1.03386 beta-lactamase_39_V157H,beta-lactamase_39_157,TEM-1,beta-lactamase_39,P62593,1.03387,NO,157,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.751,-3.319,1.568,,0.308,S,a,0.44,-0.75,10.364,10.364,69.58,BHP,-2.00767,0.0495842,0.00506849,1.03387 beta-lactamase_39_T107C,beta-lactamase_39_107,TEM-1,beta-lactamase_39,P62593,1.03388,NO,107,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.117,-4.664,3.547,,,G,A,0.22,-0.06,2.686,,67.83,HPA,-1.265,0.0495842,0.00239347,1.03388 Pab1_V198I,Pab1_198,Pab1,Pab1,P04147,1.03389,NO,198,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.113,-2.477,1.364,,0.008,E,B,0.61,0.91,,,,HHH,-1.32933,0.175299,0.000268557,1.03389 beta-lactamase_39_F149A,beta-lactamase_39_149,TEM-1,beta-lactamase_39,P62593,1.03391,NO,149,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.299,-3.341,2.042,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.0495842,0.00418462,1.03391 beta-lactamase_39_L219D,beta-lactamase_39_219,TEM-1,beta-lactamase_39,P62593,1.03396,NO,219,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.313,-4.126,2.813,,,I,A,0.55,-0.51,19.842,19.842,74.48,HHB,-1.21533,0.0495842,0.00664345,1.03396 beta-lactamase_39_A225D,beta-lactamase_39_225,TEM-1,beta-lactamase_39,P62593,1.03402,NO,225,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.845,-2.561,0.716,,1,T,B,0.46,-0.38,9.874,9.874,74.48,OHO,-1.39967,0.0495842,0.00465057,1.03402 beta-lactamase_39_P217T,beta-lactamase_39_217,TEM-1,beta-lactamase_39,P62593,1.03403,NO,217,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-2.062,-2.679,0.617,,0.496,I,A,0.52,-0.33,21.172,21.172,74.48,OOH,-1.64333,0.0495842,0.00463211,1.03403 Pab1_Q194N,Pab1_194,Pab1,Pab1,P04147,1.03404,NO,194,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.179,-2.566,0.387,,,,,,,,,,OPA,-1.59767,0.175299,0.0016145,1.03404 beta-lactamase_156_I285V,beta-lactamase_156_285,TEM-1,beta-lactamase_156,P62593,1.03405,NO,285,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.111618,0.101555,1.03405 beta-lactamase_39_G216N,beta-lactamase_39_216,TEM-1,beta-lactamase_39,P62593,1.03405,NO,216,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.477,-2.771,1.294,,0.437,I,A,0.29,-0.58,0.834,,74.48,HOO,-1.68067,0.0495842,0.00639568,1.03405 kka2_1:4_P128L,kka2_1:4_128,Kka2,kka2_1:4,P00552,1.03407,NO,128,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.922,-2.383,0.461,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.168804,0.00774689,1.03407 beta-lactamase_156_E26S,beta-lactamase_156_26,TEM-1,beta-lactamase_156,P62593,1.03409,NO,26,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.454,-3.34,0.886,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.111618,0.00297948,1.03409 gb1_E241C,gb1_241,gb1,gb1,P06654,1.03409,NO,241,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.672,-4.575,2.903,,,,,,,0.344,,11.83,OAP,-1.27933,0.177985,0.00250604,1.03409 gb1_E241F,gb1_241,gb1,gb1,P06654,1.03409,NO,241,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.672,-3.984,2.312,,,,,,,0.344,,11.83,OAP,-1.27933,0.177985,0.00250604,1.03409 gb1_T275C,gb1_275,gb1,gb1,P06654,1.03409,NO,275,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.727,-4.633,2.906,,,,,,,0.511,,35.71,HPB,-1.637,0.177985,0.00606618,1.03409 beta-lactamase_156_A170Q,beta-lactamase_156_170,TEM-1,beta-lactamase_156,P62593,1.0341,NO,170,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.237,-4.086,2.849,,0.126,,L,0.46,-0.35,3.7,,64.69,AHH,-1.63267,0.111618,0.00431903,1.0341 PSD95pdz3_G364L,PSD95pdz3_364,PSD95pdz3,PSD95pdz3,P31016,1.03413,NO,364,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.008,-3.49,2.482,5.53299,,,,,21.28,,,,POH,-1.33667,0.0758425,0.00050942,1.03413 Pab1_N187M,Pab1_187,Pab1,Pab1,P04147,1.03415,NO,187,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-1.224,-4.626,3.402,,0.456,S,b,,1.87,,,,HPO,-1.272,0.175299,0.00083165,1.03415 beta-lactamase_39_R220I,beta-lactamase_39_220,TEM-1,beta-lactamase_39,P62593,1.03417,NO,220,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-0.942,-3.974,3.032,,0.295,I,A,1.2,-0.76,1.596,,74.48,HBP,-1.33633,0.0495842,0.00232421,1.03417 beta-lactamase_625_E87D,beta-lactamase_625_87,TEM-1,beta-lactamase_625,P62593,1.03419,NO,87,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.421,-2.265,0.844,,0.048,,B,1.04,0.92,17.923,17.923,64.69,PAP,-1.969,0.213352,0.00337888,1.03419 PSD95pdz3_L360M,PSD95pdz3_360,PSD95pdz3,PSD95pdz3,P31016,1.03419,NO,360,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.431,-2.279,0.848,5.09284,,,,,14.2425,1.419,,86.88,HHP,-1.52667,0.0758425,0.000770471,1.03419 kka2_1:8_R38T,kka2_1:8_38,Kka2,kka2_1:8,P00552,1.03421,NO,38,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.207,-3.514,2.307,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.100394,0.00372499,1.03421 kka2_1:8_R38T,kka2_1:8_38,Kka2,kka2_1:8,P00552,1.03421,NO,38,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.207,-3.514,2.307,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.100394,0.00372499,1.03421 beta-lactamase_156_S221M,beta-lactamase_156_221,TEM-1,beta-lactamase_156,P62593,1.03427,NO,221,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.754,-4.595,2.841,,0.624,H,A,0.27,-0.2,17.729,17.729,74.48,BPH,-1.59967,0.111618,0.0046094,1.03427 kka2_1:4_E235A,kka2_1:4_235,Kka2,kka2_1:4,P00552,1.03428,NO,235,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.955,-1.909,-0.046,,0.631,H,A,1.04,0.12,23.175,23.175,65.53,OAH,-2.07267,0.168804,0.0102806,1.03428 Pab1_E161N,Pab1_161,Pab1,Pab1,P04147,1.03428,NO,161,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.474,-2.372,0.898,,0.663,T,a,,1.34,,,,AAP,-1.59067,0.175299,0.00276141,1.03428 kka2_1:8_G201D,kka2_1:8_201,Kka2,kka2_1:8,P00552,1.03429,NO,201,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.56,-2.294,0.734,,0.149,T,l,0.75,-0.57,2.152,,52.65,POB,-1.92233,0.100394,0.00820117,1.03429 kka2_1:8_G201D,kka2_1:8_201,Kka2,kka2_1:8,P00552,1.03429,NO,201,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.56,-2.294,0.734,,0.149,T,l,0.75,-0.57,2.152,,52.65,POB,-1.92233,0.100394,0.00820117,1.03429 beta-lactamase_156_S283I,beta-lactamase_156_283,TEM-1,beta-lactamase_156,P62593,1.0343,NO,283,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.638,-3.539,1.901,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.111618,0.0429138,1.0343 beta-lactamase_625_I45C,beta-lactamase_625_45,TEM-1,beta-lactamase_625,P62593,1.03431,NO,45,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-2.421,-4.903,2.482,,,E,B,0.48,-0.3,3.642,,77.62,HHA,-2.30267,0.213352,0.00452842,1.03431 kka2_1:4_G43C,kka2_1:4_43,Kka2,kka2_1:4,P00552,1.03432,NO,43,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.587,-3.529,1.942,,0.862,T,l,0.75,-0.67,2.247,,63.26,POB,-2.18533,0.168804,0.0071925,1.03432 beta-lactamase_0_A132I,beta-lactamase_0_132,TEM-1,beta-lactamase_0,P62593,1.03433,NO,132,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.9,-3.489,2.589,,,H,A,0.46,-0.93,2.249,,64.69,PHH,-1.138,0.0500837,0.000962524,1.03433 beta-lactamase_0_K286G,beta-lactamase_0_286,TEM-1,beta-lactamase_0,P62593,1.03433,NO,286,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.0500837,,1.03433 gb1_A274G,gb1_274,gb1,gb1,P06654,1.03435,NO,274,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.728,-2.98,1.252,,,,,,,4.162,4.162,11.83,AHP,-1.81767,0.177985,0.0068419,1.03435 beta-lactamase_0_T198C,beta-lactamase_0_198,TEM-1,beta-lactamase_0,P62593,1.03436,NO,198,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.168,-4.902,2.734,,0.489,,B,0.22,-0.13,9.874,,73.78,HPH,-1.98767,0.0500837,0.004311,1.03436 beta-lactamase_2500_K190N,beta-lactamase_2500_190,TEM-1,beta-lactamase_2500,P62593,1.0344,NO,190,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.994,-2.601,0.607,,0.371,H,A,2.34,0.16,29.753,29.753,77.62,BBH,-1.64167,0.361275,0.00574527,1.0344 kka2_1:2_G55D,kka2_1:2_55,Kka2,kka2_1:2,P00552,1.0344,NO,55,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.625,-2.304,0.679,,0.517,S,b,0.75,1.19,15.753,15.753,63.64,POH,-2.05967,0.295029,0.00667877,1.0344 beta-lactamase_625_R239Y,beta-lactamase_625_239,TEM-1,beta-lactamase_625,P62593,1.03444,NO,239,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.213352,0.00213852,1.03444 beta-lactamase_625_T138M,beta-lactamase_625_138,TEM-1,beta-lactamase_625,P62593,1.03445,NO,138,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.506,-4.821,2.315,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.213352,0.00487868,1.03445 beta-lactamase_A23A,beta-lactamase_23,TEM-1,beta-lactamase,P62593,1.03445,NO,23,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.548,-1.548,,,,,,,,0.801,,93.01,HHB,-2.235,0.221079,0.00245563,1.03445 beta-lactamase_I171H,beta-lactamase_171,TEM-1,beta-lactamase,P62593,1.03445,NO,171,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-2.431,-4.817,2.386,5.22771,0.361,,B,1,0.53,1.66,,77.62,HHO,-1.55533,0.221079,0.00623355,1.03445 beta-lactamase_I171Q,beta-lactamase_171,TEM-1,beta-lactamase,P62593,1.03445,NO,171,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-2.431,-3.168,0.737,5.22771,0.361,,B,1,0.53,1.66,,77.62,HHO,-1.55533,0.221079,0.00623355,1.03445 beta-lactamase_L192L,beta-lactamase_192,TEM-1,beta-lactamase,P62593,1.03445,NO,192,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.254,-1.254,,5.68899,0.095,H,A,1.3,0.35,1.756,,60.14,HHP,-1.41833,0.221079,0.00558728,1.03445 beta-lactamase_L196H,beta-lactamase_196,TEM-1,beta-lactamase,P62593,1.03445,NO,196,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-2.478,-3.478,1,,0.518,S,A,0.55,1.35,,,77.62,AHH,-1.839,0.221079,0.00512144,1.03445 beta-lactamase_Q274W,beta-lactamase_274,TEM-1,beta-lactamase,P62593,1.03445,NO,274,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.082,-5.326,3.244,5.6671,0.066,H,A,0.11,-0.27,2.354,,64.69,BPH,-1.931,0.221079,0.0110418,1.03445 beta-lactamase_S2H,beta-lactamase_2,TEM-1,beta-lactamase,P62593,1.03445,NO,2,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.942,-4.574,2.632,,,,,,,2.36,,65.38,HPH,-2.02767,0.221079,0.00227352,1.03445 beta-lactamase_T193A,beta-lactamase_193,TEM-1,beta-lactamase,P62593,1.03445,NO,193,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.914,-2.618,0.704,5.67952,0.439,H,a,0.3,0.33,1.863,,63.99,HPO,-1.52133,0.221079,0.00482669,1.03445 beta-lactamase_V157D,beta-lactamase_157,TEM-1,beta-lactamase,P62593,1.03445,NO,157,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.751,-3.908,2.157,5.51733,0.308,S,a,0.96,-0.75,1.847,,69.58,BHP,-2.00767,0.221079,0.00506849,1.03445 gb1_D272L,gb1_272,gb1,gb1,P06654,1.03448,NO,272,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.457,-3.555,2.098,,,,,,,0.234,,11.83,HAA,-1.54533,0.177985,0.00218257,1.03448 beta-lactamase_156_D212A,beta-lactamase_156_212,TEM-1,beta-lactamase_156,P62593,1.03452,NO,212,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.624,-2.64,1.016,,0.037,,b,0.75,-0.58,20.222,20.222,74.48,HAB,-1.77667,0.111618,0.00644302,1.03452 beta-lactamase_625_A148I,beta-lactamase_625_148,TEM-1,beta-lactamase_625,P62593,1.03452,NO,148,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.757,-4.049,2.292,,0.379,H,A,0.46,-0.55,1.359,,72.73,PHH,-1.40167,0.213352,0.00547053,1.03452 PSD95pdz3_A390T,PSD95pdz3_390,PSD95pdz3,PSD95pdz3,P31016,1.03453,NO,390,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.307,-2.878,1.571,5.03823,,,,,12.46,,,,HHP,-1.54467,0.0758425,0.00104603,1.03453 beta-lactamase_39_P255M,beta-lactamase_39_255,TEM-1,beta-lactamase_39,P62593,1.03458,NO,255,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.0495842,0.00499612,1.03458 beta-lactamase_156_G194K,beta-lactamase_156_194,TEM-1,beta-lactamase_156,P62593,1.03459,NO,194,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.396,-3.557,2.161,,0.276,S,b,0.29,0.36,1.346,,67.83,POA,-1.832,0.111618,0.00392163,1.03459 beta-lactamase_0_A222I,beta-lactamase_0_222,TEM-1,beta-lactamase_0,P62593,1.03461,NO,222,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.103,-3.632,1.529,,0.233,H,A,0.46,-0.25,2.015,,77.62,PHH,-1.63733,0.0500837,0.00466094,1.03461 beta-lactamase_0_N130A,beta-lactamase_0_130,TEM-1,beta-lactamase_0,P62593,1.03461,NO,130,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-0.798,-3.303,2.505,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.0500837,0.000683376,1.03461 beta-lactamase_156_D212T,beta-lactamase_156_212,TEM-1,beta-lactamase_156,P62593,1.03462,NO,212,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.624,-2.54,0.916,,0.037,,b,0.75,-0.58,20.222,20.222,74.48,HAB,-1.77667,0.111618,0.00644302,1.03462 kka2_1:2_G55T,kka2_1:2_55,Kka2,kka2_1:2,P00552,1.03464,NO,55,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.625,-3.642,2.017,,0.517,S,b,0.75,1.19,15.753,15.753,63.64,POH,-2.05967,0.295029,0.00667877,1.03464 WW_domain_A175T,WW_domain_175,Yap65,WW_domain,P46937,1.03464,NO,175,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.631,-3.234,1.603,6.69537,,,,,,6.257,,83.93,OHO,-1.30033,0.153962,0.00326874,1.03464 beta-lactamase_L19V,beta-lactamase_19,TEM-1,beta-lactamase,P62593,1.03469,NO,19,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.682,-2.234,0.552,,,,,,,4.261,,93.01,OHO,-1.894,0.221079,0.00215974,1.03469 kka2_1:4_V198A,kka2_1:4_198,Kka2,kka2_1:4,P00552,1.03469,NO,198,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.719,-1.379,-0.34,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.168804,0.00835002,1.03469 beta-lactamase_39_L160H,beta-lactamase_39_160,TEM-1,beta-lactamase_39,P62593,1.0347,NO,160,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.977,-4.948,3.971,,0.022,,B,0.55,-0.6,0.895,,44.41,BHA,-0.936,0.0495842,0.00193775,1.0347 beta-lactamase_0_A230M,beta-lactamase_0_230,TEM-1,beta-lactamase_0,P62593,1.03471,NO,230,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.154,-4.69,3.536,,0.01,E,B,0.46,-1.17,2.179,,50,HHA,-1.079,0.0500837,0.00516841,1.03471 beta-lactamase_156_T186N,beta-lactamase_156_186,TEM-1,beta-lactamase_156,P62593,1.03471,NO,186,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.522,-3.756,1.234,,0.396,H,A,0.22,-0.28,16.606,16.606,77.62,HPP,-1.77633,0.111618,0.00485034,1.03471 beta-lactamase_39_E108I,beta-lactamase_39_108,TEM-1,beta-lactamase_39,P62593,1.03476,NO,108,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.46,-4.133,2.673,,0.572,G,A,1.04,1.87,20.151,20.151,72.73,PAB,-1.437,0.0495842,0.00413372,1.03476 beta-lactamase_0_F70Y,beta-lactamase_0_70,TEM-1,beta-lactamase_0,P62593,1.03478,NO,70,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.169,-2.563,1.394,,,H,A,0.58,-1.34,2.153,,63.99,PHB,-0.980667,0.0500837,0.00193499,1.03478 PSD95pdz3_E352A,PSD95pdz3_352,PSD95pdz3,PSD95pdz3,P31016,1.03479,NO,352,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.587,-1.776,0.189,5.49659,,,,,24.2,2.525,,86.88,OAH,-1.314,0.0758425,0.000892231,1.03479 beta-lactamase_39_E26S,beta-lactamase_39_26,TEM-1,beta-lactamase_39,P62593,1.03481,NO,26,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.454,-3.34,0.886,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.0495842,0.00297948,1.03481 kka2_1:4_P12L,kka2_1:4_12,Kka2,kka2_1:4,P00552,1.03481,NO,12,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.853,-3.533,2.68,,,,B,0.52,1.25,0.843,,48.11,POH,-1.80767,0.168804,0.00500011,1.03481 beta-lactamase_39_F228D,beta-lactamase_39_228,TEM-1,beta-lactamase_39,P62593,1.03482,NO,228,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-2.342,-3.807,1.465,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.0495842,0.0046669,1.03482 beta-lactamase_625_Q88Y,beta-lactamase_625_88,TEM-1,beta-lactamase_625,P62593,1.03484,NO,88,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.086,-4.349,2.263,,0.807,,B,0.64,2.03,1.84,,77.62,APH,-1.53433,0.213352,0.00504167,1.03484 beta-lactamase_625_F58C,beta-lactamase_625_58,TEM-1,beta-lactamase_625,P62593,1.03485,NO,58,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-2.914,-5.093,2.179,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.213352,0.00523369,1.03485 beta-lactamase_D36R,beta-lactamase_36,TEM-1,beta-lactamase,P62593,1.03485,NO,36,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.732,-2.847,0.115,5.39764,0.555,H,A,0.11,1.17,13.689,13.689,77.62,AAP,-1.91167,0.221079,0.00476483,1.03485 beta-lactamase_0_L38F,beta-lactamase_0_38,TEM-1,beta-lactamase_0,P62593,1.03486,NO,38,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.343,-3.81,2.467,,0.088,H,A,0.55,0.2,13.556,13.556,64.34,PHO,-1.78033,0.0500837,0.00373244,1.03486 kka2_1:4_E3V,kka2_1:4_3,Kka2,kka2_1:4,P00552,1.03486,NO,3,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.199,-3.503,1.304,,,,,,,7.22,,92.05,HAP,-2.11567,0.168804,0.00267607,1.03486 beta-lactamase_0_L100P,beta-lactamase_0_100,TEM-1,beta-lactamase_0,P62593,1.0349,NO,100,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.218,-4.169,2.951,,0.343,,B,0.55,0.13,1.373,,63.29,AHH,-1.23467,0.0500837,0.00413885,1.0349 beta-lactamase_39_L199I,beta-lactamase_39_199,TEM-1,beta-lactamase_39,P62593,1.0349,NO,199,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-2.942,-3.16,0.218,,0.832,H,A,0.55,0.42,15.504,15.504,77.62,PHH,-2.32933,0.0495842,0.0048649,1.0349 PSD95pdz3_L349D,PSD95pdz3_349,PSD95pdz3,PSD95pdz3,P31016,1.0349,NO,349,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.347,-3.825,2.478,5.14696,,,,,24.6438,,,,AHP,-1.37667,0.0758425,0.00071841,1.0349 beta-lactamase_0_N168Q,beta-lactamase_0_168,TEM-1,beta-lactamase_0,P62593,1.03494,NO,168,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-1.029,-3.749,2.72,,0.113,G,A,0.61,-0.4,0.881,,44.41,HPA,-1.13233,0.0500837,0.00288667,1.03494 beta-lactamase_39_L55K,beta-lactamase_39_55,TEM-1,beta-lactamase_39,P62593,1.03495,NO,55,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.86,-3.791,1.931,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.0495842,0.00403741,1.03495 beta-lactamase_156_S256M,beta-lactamase_156_256,TEM-1,beta-lactamase_156,P62593,1.03496,NO,256,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.111618,0.00710634,1.03496 beta-lactamase_A16S,beta-lactamase_16,TEM-1,beta-lactamase,P62593,1.03496,NO,16,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,,-3.234,1.299,,,,,,,,,,HHH,,0.221079,0.00245392,1.03496 beta-lactamase_A15G,beta-lactamase_15,TEM-1,beta-lactamase,P62593,1.03497,NO,15,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.654,-3.206,1.552,,,,,,,31.998,31.998,93.01,HHH,-2.10833,0.221079,0.00248966,1.03497 beta-lactamase_156_I171P,beta-lactamase_156_171,TEM-1,beta-lactamase_156,P62593,1.03498,NO,171,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-2.431,-4.052,1.621,,0.361,,B,0.48,0.53,3.869,,77.62,HHO,-1.55533,0.111618,0.00623355,1.03498 beta-lactamase_39_Q88N,beta-lactamase_39_88,TEM-1,beta-lactamase_39,P62593,1.035,NO,88,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.086,-2.735,0.649,,0.807,,B,0.64,2.03,11.108,11.108,77.62,APH,-1.53433,0.0495842,0.00504167,1.035 gb1_D272Q,gb1_272,gb1,gb1,P06654,1.035,NO,272,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.457,-3.407,1.95,,,,,,,0.234,,11.83,HAA,-1.54533,0.177985,0.00218257,1.035 kka2_1:4_V49L,kka2_1:4_49,Kka2,kka2_1:4,P00552,1.03503,NO,49,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.614,-1.314,-0.3,,,E,B,0.44,-0.77,1.233,,64.39,HHB,-1.3,0.168804,0.00615685,1.03503 kka2_1:4_D183R,kka2_1:4_183,Kka2,kka2_1:4,P00552,1.03505,NO,183,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.204,-2.951,1.747,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.168804,0.00426304,1.03505 PSD95pdz3_G356W,PSD95pdz3_356,PSD95pdz3,PSD95pdz3,P31016,1.03505,NO,356,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.008,-4.779,3.771,4.8656,,,,,11.9575,,,,BOA,-1.22933,0.0758425,0.000623061,1.03505 kka2_1:8_H106I,kka2_1:8_106,Kka2,kka2_1:8,P00552,1.03506,NO,106,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-3.13,-4.034,0.904,,1.065,,a,0.87,-0.95,15.956,15.956,71.59,PBH,-2.10433,0.100394,0.00730778,1.03506 kka2_1:8_H106I,kka2_1:8_106,Kka2,kka2_1:8,P00552,1.03506,NO,106,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-3.13,-4.034,0.904,,1.065,,a,0.87,-0.95,15.956,15.956,71.59,PBH,-2.10433,0.100394,0.00730778,1.03506 beta-lactamase_156_E108M,beta-lactamase_156_108,TEM-1,beta-lactamase_156,P62593,1.03507,NO,108,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.46,-4.775,3.315,,0.572,G,A,1.04,1.87,8.602,8.602,72.73,PAB,-1.437,0.111618,0.00413372,1.03507 beta-lactamase_39_F70I,beta-lactamase_39_70,TEM-1,beta-lactamase_39,P62593,1.03507,NO,70,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.169,-3.353,2.184,,,H,A,0.58,-1.34,1.14,,63.99,PHB,-0.980667,0.0495842,0.00193499,1.03507 beta-lactamase_156_I285C,beta-lactamase_156_285,TEM-1,beta-lactamase_156,P62593,1.03511,NO,285,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.111618,0.101555,1.03511 beta-lactamase_0_S201M,beta-lactamase_0_201,TEM-1,beta-lactamase_0,P62593,1.03512,NO,201,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.183,-4.493,3.31,,0.064,H,A,0.27,-0.07,3.54,,64.69,HPB,-1.451,0.0500837,0.00198815,1.03512 beta-lactamase_P20Q,beta-lactamase_20,TEM-1,beta-lactamase,P62593,1.03512,NO,20,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.74,-3.914,2.174,,,,,,,0.368,,67.83,HOH,-1.765,0.221079,0.00235322,1.03512 gb1_D248R,gb1_248,gb1,gb1,P06654,1.03513,NO,248,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.569,-3.625,2.056,,,,,,,0.344,,11.83,HAH,-1.673,0.177985,0.001865,1.03513 kka2_1:8_D227V,kka2_1:8_227,Kka2,kka2_1:8,P00552,1.03513,NO,227,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.758,-3.661,1.903,,0.128,H,A,0.75,-0.63,0.281,,56.06,BAH,-1.43067,0.100394,0.00745029,1.03513 kka2_1:8_D227V,kka2_1:8_227,Kka2,kka2_1:8,P00552,1.03513,NO,227,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.758,-3.661,1.903,,0.128,H,A,0.75,-0.63,0.281,,56.06,BAH,-1.43067,0.100394,0.00745029,1.03513 beta-lactamase_39_A200F,beta-lactamase_39_200,TEM-1,beta-lactamase_39,P62593,1.03514,NO,200,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.878,-4.397,2.519,,0.757,H,A,0.46,-0.19,1.54,,77.62,HHP,-2.001,0.0495842,0.0060056,1.03514 beta-lactamase_0_E164T,beta-lactamase_0_164,TEM-1,beta-lactamase_0,P62593,1.03517,NO,164,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-0.948,-3.491,2.543,,0.011,T,B,1.04,-0.4,1.011,,64.69,HAO,-1.388,0.0500837,0.00137286,1.03517 beta-lactamase_625_P255N,beta-lactamase_625_255,TEM-1,beta-lactamase_625,P62593,1.03518,NO,255,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.213352,0.00499612,1.03518 beta-lactamase_39_L218Y,beta-lactamase_39_218,TEM-1,beta-lactamase_39,P62593,1.0352,NO,218,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.391,-4.087,2.696,,,I,b,0.55,-0.53,2.038,,74.48,OHH,-1.58867,0.0495842,0.00618274,1.0352 beta-lactamase_39_I285G,beta-lactamase_39_285,TEM-1,beta-lactamase_39,P62593,1.03521,NO,285,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.0495842,0.101555,1.03521 beta-lactamase_0_D99G,beta-lactamase_0_99,TEM-1,beta-lactamase_0,P62593,1.03522,NO,99,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.191,-3.32,2.129,,0.402,G,A,0.75,0.36,0.374,,64.69,PAH,-1.794,0.0500837,0.00305446,1.03522 beta-lactamase_39_F149H,beta-lactamase_39_149,TEM-1,beta-lactamase_39,P62593,1.03522,NO,149,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.299,-4.304,3.005,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.0495842,0.00418462,1.03522 beta-lactamase_39_L150F,beta-lactamase_39_150,TEM-1,beta-lactamase_39,P62593,1.03522,NO,150,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.326,-3.884,2.558,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.0495842,0.00463171,1.03522 kka2_1:4_A78T,kka2_1:4_78,Kka2,kka2_1:4,P00552,1.03522,NO,78,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.744,-3.425,1.681,,0.078,.,B,0.46,-0.53,0.594,,56.06,OHH,-1.863,0.168804,0.00457299,1.03522 PSD95pdz3_R313S,PSD95pdz3_313,PSD95pdz3,PSD95pdz3,P31016,1.03524,NO,313,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.582,-3.067,1.485,6.63563,,,,,18.3955,,,,BBH,-1.59733,0.0758425,0.000840067,1.03524 beta-lactamase_V8K,beta-lactamase_8,TEM-1,beta-lactamase,P62593,1.03527,NO,8,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-2.358,-3.414,1.056,,,,,,,0.575,,77.62,BHH,-2.06267,0.221079,0.00226401,1.03527 beta-lactamase_39_R92C,beta-lactamase_39_92,TEM-1,beta-lactamase_39,P62593,1.03528,NO,92,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.718,-5.119,3.401,,0.479,E,B,1.2,1.36,0.389,,65.38,BBH,-1.50367,0.0495842,0.00429626,1.03528 beta-lactamase_39_A282T,beta-lactamase_39_282,TEM-1,beta-lactamase_39,P62593,1.0353,NO,282,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.0495842,0.0449821,1.0353 beta-lactamase_D36G,beta-lactamase_36,TEM-1,beta-lactamase,P62593,1.0353,NO,36,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.732,-2.829,0.097,5.39764,0.555,H,A,0.11,1.17,13.689,13.689,77.62,AAP,-1.91167,0.221079,0.00476483,1.0353 kka2_1:2_A9T,kka2_1:2_9,Kka2,kka2_1:2,P00552,1.03532,NO,9,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.079,-3.282,1.203,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.295029,0.00273264,1.03532 PSD95pdz3_G351C,PSD95pdz3_351,PSD95pdz3,PSD95pdz3,P31016,1.03532,NO,351,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.008,-4.769,3.761,5.44798,,,,,20.7625,,,,POA,-1.37133,0.0758425,0.000691282,1.03532 beta-lactamase_T138V,beta-lactamase_138,TEM-1,beta-lactamase,P62593,1.03533,NO,138,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.506,-3.689,1.183,5.52585,0.662,H,A,0.3,-0.03,30.445,30.445,73.78,HPP,-1.81233,0.221079,0.00487868,1.03533 Pab1_E195T,Pab1_195,Pab1,Pab1,P04147,1.03536,NO,195,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.2,-3.292,2.092,,,,,,,,,,PAH,-1.72467,0.175299,0.000620107,1.03536 beta-lactamase_0_R273I,beta-lactamase_0_273,TEM-1,beta-lactamase_0,P62593,1.0354,NO,273,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.314,-4.08,1.766,,0.564,H,A,1.2,1.57,20.248,20.248,73.78,ABP,-1.841,0.0500837,0.0077952,1.0354 beta-lactamase_39_C75I,beta-lactamase_39_75,TEM-1,beta-lactamase_39,P62593,1.0354,NO,75,C,I,CI,Special,Hydrophobic,5.07,6.02,0.95,198,121,131,10,108.5,166.7,58.2,-1.245,-3.708,2.463,,,H,A,0.46,-0.87,2.369,,50,HOO,-1.24333,0.0495842,0.0034616,1.0354 beta-lactamase_I171E,beta-lactamase_171,TEM-1,beta-lactamase,P62593,1.03545,NO,171,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-2.431,-3.643,1.212,5.22771,0.361,,B,1,0.53,1.66,,77.62,HHO,-1.55533,0.221079,0.00623355,1.03545 PSD95pdz3_I389F,PSD95pdz3_389,PSD95pdz3,PSD95pdz3,P31016,1.03546,NO,389,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.628,-3.478,1.85,5.15116,,,,,14.8038,1.498,,87.71,HHH,-1.52167,0.0758425,0.00148097,1.03546 beta-lactamase_0_L74Y,beta-lactamase_0_74,TEM-1,beta-lactamase_0,P62593,1.03549,NO,74,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.296,-4.105,2.809,,,H,A,0.55,-0.91,1.46,,50,HHO,-1.34933,0.0500837,0.00493255,1.03549 beta-lactamase_0_T112P,beta-lactamase_0_112,TEM-1,beta-lactamase_0,P62593,1.03549,NO,112,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.186,-3.939,1.753,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.0500837,0.00531334,1.03549 kka2_1:2_A14G,kka2_1:2_14,Kka2,kka2_1:2,P00552,1.03549,NO,14,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.837,-2.323,0.486,,0.728,G,A,0.46,0.7,0.36,,71.59,HHH,-1.82567,0.295029,0.00706614,1.03549 kka2_1:8_L103M,kka2_1:8_103,Kka2,kka2_1:8,P00552,1.0355,NO,103,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-2.362,-4.518,2.156,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.100394,0.00574792,1.0355 kka2_1:8_L103M,kka2_1:8_103,Kka2,kka2_1:8,P00552,1.0355,NO,103,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-2.362,-4.518,2.156,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.100394,0.00574792,1.0355 beta-lactamase_39_T126H,beta-lactamase_39_126,TEM-1,beta-lactamase_39,P62593,1.03551,NO,126,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.122,-4.699,3.577,,0.05,H,A,0.22,-0.05,0.586,,44.41,HPH,-1.60467,0.0495842,0.00244552,1.03551 kka2_1:2_T28K,kka2_1:2_28,Kka2,kka2_1:2,P00552,1.03552,NO,28,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.883,-3.68,1.797,,0.353,S,B,0.22,2.02,2.655,,63.64,PPH,-1.74467,0.295029,0.00743084,1.03552 beta-lactamase_39_C75L,beta-lactamase_39_75,TEM-1,beta-lactamase_39,P62593,1.03554,NO,75,C,L,CL,Special,Hydrophobic,5.07,9.7088,4.6388,198,121,131,10,108.5,166.7,58.2,-1.245,-3.28,2.035,,,H,A,0.46,-0.87,2.369,,50,HOO,-1.24333,0.0495842,0.0034616,1.03554 beta-lactamase_625_E87Q,beta-lactamase_625_87,TEM-1,beta-lactamase_625,P62593,1.03554,NO,87,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.421,-2.648,1.227,,0.048,,B,1.04,0.92,17.923,17.923,64.69,PAP,-1.969,0.213352,0.00337888,1.03554 hsp90_M589Q,hsp90_589,hsp90,hsp90,P02829,1.03554,NO,589,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-3.858,-3.278,0,4.72723,0.032,H,A,0.84,0.31,,,,PHA,-3.24233,0.368192,0.000222939,1.03554 beta-lactamase_39_Q267D,beta-lactamase_39_267,TEM-1,beta-lactamase_39,P62593,1.03555,NO,267,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.0495842,0.0102128,1.03555 Pab1_D184R,Pab1_184,Pab1,Pab1,P04147,1.03555,NO,184,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.5,-3.547,2.047,,,,,,,,,,HAH,-1.50133,0.175299,0.0011931,1.03555 kka2_1:4_R18P,kka2_1:4_18,Kka2,kka2_1:4,P00552,1.03556,NO,18,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.055,-4.134,2.079,,0.474,T,A,1.2,0.54,8.405,8.405,71.59,ABH,-1.821,0.168804,0.00724065,1.03556 Pab1_D184L,Pab1_184,Pab1,Pab1,P04147,1.03556,NO,184,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.5,-3.565,2.065,,,,,,,,,,HAH,-1.50133,0.175299,0.0011931,1.03556 beta-lactamase_625_M209C,beta-lactamase_625_209,TEM-1,beta-lactamase_625,P62593,1.03557,NO,209,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.442,-4.758,3.316,,,H,A,0.55,-0.97,1.167,,64.69,HHA,-1.52633,0.213352,0.00625021,1.03557 PSD95pdz3_Q384L,PSD95pdz3_384,PSD95pdz3,PSD95pdz3,P31016,1.03557,NO,384,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-1.699,-3.04,1.341,5.49339,,,,,23.54,,,,OPP,-1.41333,0.0758425,0.000216736,1.03557 PSD95pdz3_T387W,PSD95pdz3_387,PSD95pdz3,PSD95pdz3,P31016,1.03559,NO,387,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.391,-4.779,3.388,5.20757,,,,,18.8043,,,,HPH,-1.49533,0.0758425,0.000167911,1.03559 PSD95pdz3_G351T,PSD95pdz3_351,PSD95pdz3,PSD95pdz3,P31016,1.03561,NO,351,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.008,-3.328,2.32,5.44798,,,,,20.7625,,,,POA,-1.37133,0.0758425,0.000691282,1.03561 beta-lactamase_2500_Q86F,beta-lactamase_2500_86,TEM-1,beta-lactamase_2500,P62593,1.03562,NO,86,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.4,-4.354,1.954,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.361275,0.00450027,1.03562 gb1_V265I,gb1_265,gb1,gb1,P06654,1.03565,NO,265,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.843,-3.116,1.273,,,,,,,0.402,,11.83,OHA,-1.64567,0.177985,0.00360613,1.03565 beta-lactamase_39_Q86Y,beta-lactamase_39_86,TEM-1,beta-lactamase_39,P62593,1.03566,NO,86,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.4,-4.372,1.972,,0.696,S,A,0.64,2.38,27.704,27.704,77.62,OPA,-1.61067,0.0495842,0.00450027,1.03566 beta-lactamase_39_T27C,beta-lactamase_39_27,TEM-1,beta-lactamase_39,P62593,1.03566,NO,27,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.905,-4.927,3.022,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.0495842,0.00306559,1.03566 beta-lactamase_39_E87D,beta-lactamase_39_87,TEM-1,beta-lactamase_39,P62593,1.03568,NO,87,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.421,-2.265,0.844,,0.048,,B,1.04,0.92,15.231,15.231,64.69,PAP,-1.969,0.0495842,0.00337888,1.03568 kka2_1:8_E235L,kka2_1:8_235,Kka2,kka2_1:8,P00552,1.03569,NO,235,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.955,-3.621,1.666,,0.631,H,A,1.52,0.12,,,65.53,OAH,-2.07267,0.100394,0.0102806,1.03569 kka2_1:8_E235L,kka2_1:8_235,Kka2,kka2_1:8,P00552,1.03569,NO,235,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.955,-3.621,1.666,,0.631,H,A,1.52,0.12,,,65.53,OAH,-2.07267,0.100394,0.0102806,1.03569 PSD95pdz3_T321W,PSD95pdz3_321,PSD95pdz3,PSD95pdz3,P31016,1.03569,NO,321,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.391,-4.779,3.388,5.19953,,,,,20.3371,,,,PPO,-1.306,0.0758425,0.00106992,1.03569 kka2_1:4_G164F,kka2_1:4_164,Kka2,kka2_1:4,P00552,1.0357,NO,164,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.869,-4.375,3.506,,0.862,T,l,0.75,1.45,1.539,,64.39,POH,-1.828,0.168804,0.00442091,1.0357 beta-lactamase_0_V78L,beta-lactamase_0_78,TEM-1,beta-lactamase_0,P62593,1.03572,NO,78,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.459,-1.714,0.255,,,H,A,0.44,-0.47,16.615,16.615,63.64,HHH,-1.17833,0.0500837,0.00492501,1.03572 beta-lactamase_39_E26R,beta-lactamase_39_26,TEM-1,beta-lactamase_39,P62593,1.03572,NO,26,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.454,-2.433,-0.021,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.0495842,0.00297948,1.03572 beta-lactamase_156_D212S,beta-lactamase_156_212,TEM-1,beta-lactamase_156,P62593,1.03573,NO,212,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.624,-2.471,0.847,,0.037,,b,0.75,-0.58,20.222,20.222,74.48,HAB,-1.77667,0.111618,0.00644302,1.03573 kka2_1:8_Q155K,kka2_1:8_155,Kka2,kka2_1:8,P00552,1.03573,NO,155,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.606,-3.316,0.71,,0.525,T,A,0.64,1.49,,,63.64,APA,-1.726,0.100394,0.00641853,1.03573 kka2_1:8_Q155K,kka2_1:8_155,Kka2,kka2_1:8,P00552,1.03573,NO,155,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.606,-3.316,0.71,,0.525,T,A,0.64,1.49,,,63.64,APA,-1.726,0.100394,0.00641853,1.03573 beta-lactamase_A15A,beta-lactamase_15,TEM-1,beta-lactamase,P62593,1.03575,NO,15,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.654,-1.654,,,,,,,,31.998,31.998,93.01,HHH,-2.10833,0.221079,0.00248966,1.03575 PSD95pdz3_D366Q,PSD95pdz3_366,PSD95pdz3,PSD95pdz3,P31016,1.03579,NO,366,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.264,-3.356,2.092,5.55684,,,,,20.2375,,,,HAH,-1.401,0.0758425,0.000481272,1.03579 PSD95pdz3_V365H,PSD95pdz3_365,PSD95pdz3,PSD95pdz3,P31016,1.03579,NO,365,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.592,-4.586,2.994,5.03791,,,,,18.9657,2.364,,81.35,OHA,-1.288,0.0758425,0.000649764,1.03579 beta-lactamase_0_Q86I,beta-lactamase_0_86,TEM-1,beta-lactamase_0,P62593,1.03583,NO,86,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.4,-3.877,1.477,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.0500837,0.00450027,1.03583 beta-lactamase_625_T138L,beta-lactamase_625_138,TEM-1,beta-lactamase_625,P62593,1.03583,NO,138,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.506,-3.638,1.132,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.213352,0.00487868,1.03583 kka2_1:8_T72V,kka2_1:8_72,Kka2,kka2_1:8,P00552,1.03584,NO,72,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.38,-3.703,1.323,,0.784,H,A,0.22,0.29,3.603,,65.53,HPP,-2.238,0.100394,0.00750756,1.03584 kka2_1:8_T72V,kka2_1:8_72,Kka2,kka2_1:8,P00552,1.03584,NO,72,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.38,-3.703,1.323,,0.784,H,A,0.22,0.29,3.603,,65.53,HPP,-2.238,0.100394,0.00750756,1.03584 PSD95pdz3_Q358L,PSD95pdz3_358,PSD95pdz3,PSD95pdz3,P31016,1.03584,NO,358,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-1.699,-3.04,1.341,5.21282,,,,,14.8844,,,,APH,-1.531,0.0758425,0.000594893,1.03584 kka2_1:8_Q42Y,kka2_1:8_42,Kka2,kka2_1:8,P00552,1.03585,NO,42,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.907,-4.454,1.547,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.100394,0.00679212,1.03585 kka2_1:8_Q42Y,kka2_1:8_42,Kka2,kka2_1:8,P00552,1.03585,NO,42,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.907,-4.454,1.547,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.100394,0.00679212,1.03585 PSD95pdz3_D357H,PSD95pdz3_357,PSD95pdz3,PSD95pdz3,P31016,1.03585,NO,357,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.264,-4.137,2.873,5.22306,,,,,10.975,,,,OAP,-1.32367,0.0758425,0.000609015,1.03585 beta-lactamase_39_D99Q,beta-lactamase_39_99,TEM-1,beta-lactamase_39,P62593,1.03587,NO,99,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.191,-2.836,1.645,,0.402,G,A,0.75,0.36,0.374,,64.69,PAH,-1.794,0.0495842,0.00305446,1.03587 beta-lactamase_625_E272W,beta-lactamase_625_272,TEM-1,beta-lactamase_625,P62593,1.03588,NO,272,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.213352,0.00545371,1.03588 PSD95pdz3_L360V,PSD95pdz3_360,PSD95pdz3,PSD95pdz3,P31016,1.03588,NO,360,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.431,-2.631,1.2,5.09284,,,,,14.2425,1.419,,86.88,HHP,-1.52667,0.0758425,0.000770471,1.03588 beta-lactamase_39_M67F,beta-lactamase_39_67,TEM-1,beta-lactamase_39,P62593,1.0359,NO,67,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-2.231,-4.128,1.897,,0.006,G,P,0.55,-0.81,1.463,,65.03,HHP,-1.502,0.0495842,0.00409753,1.0359 beta-lactamase_39_V78Q,beta-lactamase_39_78,TEM-1,beta-lactamase_39,P62593,1.03591,NO,78,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.459,-4.26,2.801,,,H,A,0.44,-0.47,1.132,,63.64,HHH,-1.17833,0.0495842,0.00492501,1.03591 gb1_D248N,gb1_248,gb1,gb1,P06654,1.03591,NO,248,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.569,-3.034,1.465,,,,,,,0.344,,11.83,HAH,-1.673,0.177985,0.001865,1.03591 beta-lactamase_0_L205W,beta-lactamase_0_205,TEM-1,beta-lactamase_0,P62593,1.03593,NO,205,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.922,-4.959,4.037,,,H,A,0.55,-0.46,1.065,,42.31,PHH,-1.57767,0.0500837,0.00255802,1.03593 beta-lactamase_39_S241Y,beta-lactamase_39_241,TEM-1,beta-lactamase_39,P62593,1.03593,NO,241,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.0495842,0.00452736,1.03593 beta-lactamase_K32Q,beta-lactamase_32,TEM-1,beta-lactamase,P62593,1.03593,NO,32,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.984,-2.601,0.617,5.55842,0.563,H,A,1.82,0.34,1.754,,73.08,HBA,-2.04233,0.221079,0.00401283,1.03593 beta-lactamase_0_P255E,beta-lactamase_0_255,TEM-1,beta-lactamase_0,P62593,1.03594,NO,255,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.0500837,0.00499612,1.03594 kka2_1:8_Q27R,kka2_1:8_27,Kka2,kka2_1:8,P00552,1.03594,NO,27,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-1.659,-3.828,2.169,,0.608,.,A,0.64,0.71,3.919,,65.53,PPP,-1.90733,0.100394,0.00595365,1.03594 kka2_1:8_Q27R,kka2_1:8_27,Kka2,kka2_1:8,P00552,1.03594,NO,27,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-1.659,-3.828,2.169,,0.608,.,A,0.64,0.71,3.919,,65.53,PPP,-1.90733,0.100394,0.00595365,1.03594 beta-lactamase_0_P250Y,beta-lactamase_0_250,TEM-1,beta-lactamase_0,P62593,1.03595,NO,250,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.0500837,0.00550899,1.03595 PSD95pdz3_A378L,PSD95pdz3_378,PSD95pdz3,PSD95pdz3,P31016,1.03596,NO,378,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.307,-2.815,1.508,4.86582,,,,,14.576,,,,HHH,-1.509,0.0758425,0.000313169,1.03596 beta-lactamase_39_F58M,beta-lactamase_39_58,TEM-1,beta-lactamase_39,P62593,1.03597,NO,58,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-2.914,-4.667,1.753,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.0495842,0.00523369,1.03597 beta-lactamase_156_R118C,beta-lactamase_156_118,TEM-1,beta-lactamase_156,P62593,1.03599,NO,118,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.413,-4.992,2.579,,0.457,H,A,1.2,1.39,2.231,,77.62,HBA,-1.785,0.111618,0.00538794,1.03599 kka2_1:4_L57Q,kka2_1:4_57,Kka2,kka2_1:4,P00552,1.03602,NO,57,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.898,-3.254,1.356,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.168804,0.00723769,1.03602 beta-lactamase_39_R91E,beta-lactamase_39_91,TEM-1,beta-lactamase_39,P62593,1.03605,NO,91,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.392,-2.211,0.819,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.0495842,0.00380226,1.03605 beta-lactamase_0_K30I,beta-lactamase_0_30,TEM-1,beta-lactamase_0,P62593,1.03606,NO,30,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-2.307,-3.856,1.549,,0.142,H,A,2.34,-0.65,1.491,,93.01,HBH,-2.32833,0.0500837,0.00448593,1.03606 beta-lactamase_156_E26I,beta-lactamase_156_26,TEM-1,beta-lactamase_156,P62593,1.03606,NO,26,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.454,-3.782,1.328,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.111618,0.00297948,1.03606 beta-lactamase_39_L191C,beta-lactamase_39_191,TEM-1,beta-lactamase_39,P62593,1.03606,NO,191,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.087,-4.696,3.609,,,H,A,0.55,0.09,1.372,,63.29,BHH,-1.445,0.0495842,0.00263549,1.03606 PSD95pdz3_Q391L,PSD95pdz3_391,PSD95pdz3,PSD95pdz3,P31016,1.03607,NO,391,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-1.699,-3.04,1.341,5.50275,,,,,12.6589,,,,HPH,-1.481,0.0758425,0.000990786,1.03607 beta-lactamase_156_A222K,beta-lactamase_156_222,TEM-1,beta-lactamase_156,P62593,1.03608,NO,222,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.103,-3.694,1.591,,0.233,H,A,0.46,-0.25,2.461,,77.62,PHH,-1.63733,0.111618,0.00466094,1.03608 kka2_1:8_P132R,kka2_1:8_132,Kka2,kka2_1:8,P00552,1.03609,NO,132,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.775,-3.959,3.184,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.100394,0.0018489,1.03609 kka2_1:8_P132R,kka2_1:8_132,Kka2,kka2_1:8,P00552,1.03609,NO,132,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.775,-3.959,3.184,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.100394,0.0018489,1.03609 beta-lactamase_2500_I45V,beta-lactamase_2500_45,TEM-1,beta-lactamase_2500,P62593,1.03611,NO,45,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-2.421,-2.178,-0.243,,,E,B,0.48,-0.3,3.793,,77.62,HHA,-2.30267,0.361275,0.00452842,1.03611 beta-lactamase_39_F70Y,beta-lactamase_39_70,TEM-1,beta-lactamase_39,P62593,1.03612,NO,70,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.169,-2.563,1.394,,,H,A,0.58,-1.34,1.14,,63.99,PHB,-0.980667,0.0495842,0.00193499,1.03612 beta-lactamase_0_L196V,beta-lactamase_0_196,TEM-1,beta-lactamase_0,P62593,1.03614,NO,196,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-2.478,-2.258,-0.22,,0.518,S,A,0.55,1.35,6.513,6.513,77.62,AHH,-1.839,0.0500837,0.00512144,1.03614 beta-lactamase_39_T187I,beta-lactamase_39_187,TEM-1,beta-lactamase_39,P62593,1.03614,NO,187,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.401,-2.871,1.47,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.0495842,0.00491782,1.03614 PSD95pdz3_G344Y,PSD95pdz3_344,PSD95pdz3,PSD95pdz3,P31016,1.03614,NO,344,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.008,-4.069,3.061,4.83855,,,,,14.06,,,,HOO,-1.10767,0.0758425,0.00078498,1.03614 gb1_D248S,gb1_248,gb1,gb1,P06654,1.03616,NO,248,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.569,-1.702,0.133,,,,,,,0.344,,11.83,HAH,-1.673,0.177985,0.001865,1.03616 beta-lactamase_2500_K32Q,beta-lactamase_2500_32,TEM-1,beta-lactamase_2500,P62593,1.03617,NO,32,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.984,-2.601,0.617,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.361275,0.00401283,1.03617 beta-lactamase_L49M,beta-lactamase_49,TEM-1,beta-lactamase,P62593,1.03617,NO,49,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.897,-4.411,2.514,5.86005,0.131,T,A,1.3,0.04,3.112,,64.69,AHP,-1.99233,0.221079,0.00401477,1.03617 beta-lactamase_156_M180N,beta-lactamase_156_180,TEM-1,beta-lactamase_156,P62593,1.03618,NO,180,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-2.795,-3.603,0.808,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.111618,0.00552048,1.03618 PSD95pdz3_Q358W,PSD95pdz3_358,PSD95pdz3,PSD95pdz3,P31016,1.03619,NO,358,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-1.699,-4.779,3.08,5.21282,,,,,14.8844,,,,APH,-1.531,0.0758425,0.000594893,1.03619 beta-lactamase_156_S201H,beta-lactamase_156_201,TEM-1,beta-lactamase_156,P62593,1.03625,NO,201,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.183,-4.595,3.412,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.111618,0.00198815,1.03625 E1_Ubiquitin_F45E,E1_Ubiquitin_45,Uba1,E1_Ubiquitin,P0CG63,1.03625,NO,45,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.149,-3.707,2.558,,0.26,E,B,,-0.99,,,,HHH,-1.316,0.18783,0.00193245,1.03625 E1_Ubiquitin_F45M,E1_Ubiquitin_45,Uba1,E1_Ubiquitin,P0CG63,1.03625,NO,45,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.149,-4.072,2.923,,0.26,E,B,,-0.99,,,,HHH,-1.316,0.18783,0.00193245,1.03625 E1_Ubiquitin_Q41C,E1_Ubiquitin_41,Uba1,E1_Ubiquitin,P0CG63,1.03625,NO,41,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-1.25,-4.904,3.654,,0.017,E,B,,-0.98,,,,PPB,-1.344,0.18783,0.00215097,1.03625 kka2_1:8_A65C,kka2_1:8_65,Kka2,kka2_1:8,P00552,1.03626,NO,65,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.744,-5.062,3.318,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.100394,0.00709258,1.03626 kka2_1:8_A65C,kka2_1:8_65,Kka2,kka2_1:8,P00552,1.03626,NO,65,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.744,-5.062,3.318,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.100394,0.00709258,1.03626 beta-lactamase_P60A,beta-lactamase_60,TEM-1,beta-lactamase,P62593,1.03627,NO,60,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-2.469,-1.436,-1.033,5.51353,0.256,T,A,0.73,-0.56,3.653,,77.62,BOA,-1.97633,0.221079,0.00521318,1.03627 beta-lactamase_0_T269G,beta-lactamase_0_269,TEM-1,beta-lactamase_0,P62593,1.03628,NO,269,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.0500837,0.00950944,1.03628 beta-lactamase_156_T193K,beta-lactamase_156_193,TEM-1,beta-lactamase_156,P62593,1.0363,NO,193,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.914,-3.726,1.812,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.111618,0.00482669,1.0363 beta-lactamase_0_L150H,beta-lactamase_0_150,TEM-1,beta-lactamase_0,P62593,1.03632,NO,150,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.326,-4.935,3.609,,,H,A,0.55,-0.2,2.128,,62.94,HHB,-1.86167,0.0500837,0.00463171,1.03632 beta-lactamase_39_R91N,beta-lactamase_39_91,TEM-1,beta-lactamase_39,P62593,1.03634,NO,91,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.392,-3.596,2.204,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.0495842,0.00380226,1.03634 kka2_1:4_H139D,kka2_1:4_139,Kka2,kka2_1:4,P00552,1.03634,NO,139,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-2.809,-3.251,0.442,,0.471,H,A,0.17,0.68,12.761,12.761,63.64,BBB,-2.22,0.168804,0.00734779,1.03634 beta-lactamase_156_I277L,beta-lactamase_156_277,TEM-1,beta-lactamase_156,P62593,1.03635,NO,277,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.111618,0.0169305,1.03635 kka2_1:4_A35D,kka2_1:4_35,Kka2,kka2_1:4,P00552,1.03635,NO,35,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.127,-2.127,0,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.168804,0.00630016,1.03635 beta-lactamase_39_I277W,beta-lactamase_39_277,TEM-1,beta-lactamase_39,P62593,1.03636,NO,277,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.0495842,0.0169305,1.03636 beta-lactamase_156_I244A,beta-lactamase_156_244,TEM-1,beta-lactamase_156,P62593,1.03637,NO,244,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.555,-3.008,1.453,,,E,B,0.48,-0.84,1.325,,77.62,OHH,-1.385,0.111618,0.00605379,1.03637 beta-lactamase_0_H156T,beta-lactamase_0_156,TEM-1,beta-lactamase_0,P62593,1.03639,NO,156,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-3.156,-2.632,-0.524,,0.753,S,A,0.17,-0.6,23.367,23.367,77.62,ABH,-1.932,0.0500837,0.00468596,1.03639 beta-lactamase_156_L223I,beta-lactamase_156_223,TEM-1,beta-lactamase_156,P62593,1.03639,NO,223,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.055,-2.996,1.941,,0.27,,B,0.55,0.09,1.511,,74.48,HHO,-1.35033,0.111618,0.00372793,1.03639 beta-lactamase_39_K32M,beta-lactamase_39_32,TEM-1,beta-lactamase_39,P62593,1.03641,NO,32,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.984,-4.613,2.629,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.0495842,0.00401283,1.03641 beta-lactamase_625_V29C,beta-lactamase_625_29,TEM-1,beta-lactamase_625,P62593,1.03641,NO,29,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-2.856,-5.117,2.261,,0.733,H,A,0.44,-0.78,1.931,,93.01,HHB,-2.24733,0.213352,0.00318969,1.03641 gb1_A274N,gb1_274,gb1,gb1,P06654,1.03642,NO,274,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.728,-3.389,1.661,,,,,,,4.162,4.162,11.83,AHP,-1.81767,0.177985,0.0068419,1.03642 PSD95pdz3_A378I,PSD95pdz3_378,PSD95pdz3,PSD95pdz3,P31016,1.03643,NO,378,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.307,-3.242,1.935,4.86582,,,,,14.576,,,,HHH,-1.509,0.0758425,0.000313169,1.03643 beta-lactamase_156_T186D,beta-lactamase_156_186,TEM-1,beta-lactamase_156,P62593,1.03644,NO,186,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.522,-2.935,0.413,,0.396,H,A,0.22,-0.28,16.606,16.606,77.62,HPP,-1.77633,0.111618,0.00485034,1.03644 kka2_1:8_E96F,kka2_1:8_96,Kka2,kka2_1:8,P00552,1.03644,NO,96,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.573,-4.257,1.684,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.100394,0.00369441,1.03644 kka2_1:8_E96F,kka2_1:8_96,Kka2,kka2_1:8,P00552,1.03644,NO,96,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.573,-4.257,1.684,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.100394,0.00369441,1.03644 beta-lactamase_156_I261M,beta-lactamase_156_261,TEM-1,beta-lactamase_156,P62593,1.03648,NO,261,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.111618,0.0123091,1.03648 beta-lactamase_625_I285S,beta-lactamase_625_285,TEM-1,beta-lactamase_625,P62593,1.03652,NO,285,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.213352,0.101555,1.03652 gb1_D272H,gb1_272,gb1,gb1,P06654,1.03655,NO,272,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.457,-4.134,2.677,,,,,,,0.234,,11.83,HAA,-1.54533,0.177985,0.00218257,1.03655 kka2_1:4_P179C,kka2_1:4_179,Kka2,kka2_1:4,P00552,1.03655,NO,179,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.974,-5.011,4.037,,0.113,,B,0.52,0.69,10.913,10.913,56.06,HOA,-2.19867,0.168804,0.00298346,1.03655 kka2_1:8_G21F,kka2_1:8_21,Kka2,kka2_1:8,P00552,1.03657,NO,21,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.368,-4.373,3.005,,0.586,T,l,0.29,-0.75,4.889,,71.59,HOH,-2.10167,0.100394,0.00709648,1.03657 kka2_1:8_G21F,kka2_1:8_21,Kka2,kka2_1:8,P00552,1.03657,NO,21,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.368,-4.373,3.005,,0.586,T,l,0.29,-0.75,4.889,,71.59,HOH,-2.10167,0.100394,0.00709648,1.03657 beta-lactamase_0_A235S,beta-lactamase_0_235,TEM-1,beta-lactamase_0,P62593,1.03658,NO,235,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.266,-2.058,0.792,,0.32,E,B,0.46,-0.86,2.261,,50,OHO,-0.89,0.0500837,0.00493474,1.03658 beta-lactamase_156_M270I,beta-lactamase_156_270,TEM-1,beta-lactamase_156,P62593,1.0366,NO,270,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.111618,0.00767762,1.0366 kka2_1:8_Y244I,kka2_1:8_244,Kka2,kka2_1:8,P00552,1.03662,NO,244,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-0.775,-3.589,2.814,,0.066,H,A,1.25,-0.64,,,,HHO,-1.41267,0.100394,0.00453187,1.03662 kka2_1:8_Y244I,kka2_1:8_244,Kka2,kka2_1:8,P00552,1.03662,NO,244,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-0.775,-3.589,2.814,,0.066,H,A,1.25,-0.64,,,,HHO,-1.41267,0.100394,0.00453187,1.03662 beta-lactamase_0_A246K,beta-lactamase_0_246,TEM-1,beta-lactamase_0,P62593,1.03663,NO,246,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.121,-3.849,1.728,,0.01,E,B,0.46,-1.01,1.201,,73.78,HHH,-1.55633,0.0500837,0.00569458,1.03663 beta-lactamase_625_V106H,beta-lactamase_625_106,TEM-1,beta-lactamase_625,P62593,1.03666,NO,106,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.218,-4.937,3.719,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.213352,0.00304168,1.03666 kka2_1:8_A110E,kka2_1:8_110,Kka2,kka2_1:8,P00552,1.03666,NO,110,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.064,-2.266,0.202,,0.175,H,A,1.04,-1.19,11.413,11.413,71.59,OHA,-1.91867,0.100394,0.00759851,1.03666 kka2_1:8_A110E,kka2_1:8_110,Kka2,kka2_1:8,P00552,1.03666,NO,110,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.064,-2.266,0.202,,0.175,H,A,1.04,-1.19,11.413,11.413,71.59,OHA,-1.91867,0.100394,0.00759851,1.03666 beta-lactamase_625_A211K,beta-lactamase_625_211,TEM-1,beta-lactamase_625,P62593,1.03667,NO,211,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.896,-3.538,1.642,,0.369,T,A,0.46,-0.69,2.061,,77.62,AHA,-1.94633,0.213352,0.00648183,1.03667 beta-lactamase_39_T131Q,beta-lactamase_39_131,TEM-1,beta-lactamase_39,P62593,1.03668,NO,131,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.328,-3.951,2.623,,,H,A,0.22,-0.69,3.306,,67.48,PPH,-1.00867,0.0495842,0.00345886,1.03668 kka2_1:8_V80H,kka2_1:8_80,Kka2,kka2_1:8,P00552,1.03668,NO,80,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.144,-4.98,3.836,,0.358,E,B,1.48,-0.24,2.562,,63.64,HHH,-1.64633,0.100394,0.00488211,1.03668 kka2_1:8_V80H,kka2_1:8_80,Kka2,kka2_1:8,P00552,1.03668,NO,80,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.144,-4.98,3.836,,0.358,E,B,1.48,-0.24,2.562,,63.64,HHH,-1.64633,0.100394,0.00488211,1.03668 beta-lactamase_39_G234M,beta-lactamase_39_234,TEM-1,beta-lactamase_39,P62593,1.03669,NO,234,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.62,-4.93,4.31,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.0495842,0.000889577,1.03669 beta-lactamase_156_A170P,beta-lactamase_156_170,TEM-1,beta-lactamase_156,P62593,1.03673,NO,170,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.237,-3.899,2.662,,0.126,,L,0.46,-0.35,3.7,,64.69,AHH,-1.63267,0.111618,0.00431903,1.03673 beta-lactamase_156_T138Y,beta-lactamase_156_138,TEM-1,beta-lactamase_156,P62593,1.03674,NO,138,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.506,-4.429,1.923,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.111618,0.00487868,1.03674 beta-lactamase_625_E272S,beta-lactamase_625_272,TEM-1,beta-lactamase_625,P62593,1.03674,NO,272,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.213352,0.00545371,1.03674 beta-lactamase_625_Q86F,beta-lactamase_625_86,TEM-1,beta-lactamase_625,P62593,1.03674,NO,86,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.4,-4.354,1.954,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.213352,0.00450027,1.03674 beta-lactamase_D33A,beta-lactamase_33,TEM-1,beta-lactamase,P62593,1.03675,NO,33,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.321,-2.241,-0.08,5.05203,0.366,H,A,0.23,0.33,2.032,,77.62,BAH,-2.12133,0.221079,0.00435556,1.03675 beta-lactamase_156_E26M,beta-lactamase_156_26,TEM-1,beta-lactamase_156,P62593,1.03676,NO,26,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.454,-4.568,2.114,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.111618,0.00297948,1.03676 beta-lactamase_39_A123I,beta-lactamase_39_123,TEM-1,beta-lactamase_39,P62593,1.0368,NO,123,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.834,-3.433,2.599,,0.039,H,A,0.46,-0.72,0.705,,41.26,PHH,-1.47367,0.0495842,0.0010157,1.0368 gb1_L233V,gb1_233,gb1,gb1,P06654,1.0368,NO,233,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-2.678,-1.751,-0.927,,,,,,,0.822,,45.54,HHP,-2.30267,0.177985,0.00266958,1.0368 beta-lactamase_156_E26N,beta-lactamase_156_26,TEM-1,beta-lactamase_156,P62593,1.03681,NO,26,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.454,-3.711,1.257,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.111618,0.00297948,1.03681 kka2_1:8_P179T,kka2_1:8_179,Kka2,kka2_1:8,P00552,1.03681,NO,179,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.974,-3.471,2.497,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.100394,0.00298346,1.03681 kka2_1:8_P179T,kka2_1:8_179,Kka2,kka2_1:8,P00552,1.03681,NO,179,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.974,-3.471,2.497,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.100394,0.00298346,1.03681 PSD95pdz3_Q358E,PSD95pdz3_358,PSD95pdz3,PSD95pdz3,P31016,1.03681,NO,358,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-1.699,-2.447,0.748,5.21282,,,,,14.8844,,,,APH,-1.531,0.0758425,0.000594893,1.03681 beta-lactamase_156_E26T,beta-lactamase_156_26,TEM-1,beta-lactamase_156,P62593,1.03682,NO,26,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.454,-2.753,0.299,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.111618,0.00297948,1.03682 beta-lactamase_39_T116E,beta-lactamase_39_116,TEM-1,beta-lactamase_39,P62593,1.03682,NO,116,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.28,-3.469,2.189,,0.115,E,B,0.22,-0.12,1.133,,67.48,HPH,-1.39967,0.0495842,0.00336175,1.03682 beta-lactamase_625_E272C,beta-lactamase_625_272,TEM-1,beta-lactamase_625,P62593,1.03682,NO,272,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.213352,0.00545371,1.03682 kka2_1:4_P98E,kka2_1:4_98,Kka2,kka2_1:4,P00552,1.03683,NO,98,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.526,-2.413,0.887,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.168804,0.00622754,1.03683 beta-lactamase_39_I258C,beta-lactamase_39_258,TEM-1,beta-lactamase_39,P62593,1.03686,NO,258,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.0495842,0.007931,1.03686 beta-lactamase_0_I140P,beta-lactamase_0_140,TEM-1,beta-lactamase_0,P62593,1.03689,NO,140,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.733,-4.152,2.419,,0.128,H,A,0.48,0.41,4.714,,73.08,PHO,-1.48733,0.0500837,0.00597777,1.03689 beta-lactamase_39_R91F,beta-lactamase_39_91,TEM-1,beta-lactamase_39,P62593,1.03689,NO,91,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.392,-4.376,2.984,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.0495842,0.00380226,1.03689 kka2_1:8_P76T,kka2_1:8_76,Kka2,kka2_1:8,P00552,1.0369,NO,76,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.449,-2.904,1.455,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.100394,0.00625685,1.0369 kka2_1:8_P76T,kka2_1:8_76,Kka2,kka2_1:8,P00552,1.0369,NO,76,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.449,-2.904,1.455,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.100394,0.00625685,1.0369 kka2_1:8_Y22H,kka2_1:8_22,Kka2,kka2_1:8,P00552,1.0369,NO,22,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-1.583,-2.746,1.163,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.100394,0.00598977,1.0369 kka2_1:8_Y22H,kka2_1:8_22,Kka2,kka2_1:8,P00552,1.0369,NO,22,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-1.583,-2.746,1.163,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.100394,0.00598977,1.0369 beta-lactamase_0_E61P,beta-lactamase_0_61,TEM-1,beta-lactamase_0,P62593,1.03691,NO,61,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.115,-3.861,1.746,,0.775,T,a,1.04,1.29,34.763,34.763,77.62,OAA,-1.92567,0.0500837,0.00440955,1.03691 beta-lactamase_0_M66L,beta-lactamase_0_66,TEM-1,beta-lactamase_0,P62593,1.03691,NO,66,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.362,-1.674,0.312,,0.013,,A,0.55,-0.7,1.204,,73.08,OHH,-1.49567,0.0500837,0.00412876,1.03691 beta-lactamase_0_N134F,beta-lactamase_0_134,TEM-1,beta-lactamase_0,P62593,1.03692,NO,134,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-0.879,-4.318,3.439,,0.138,H,A,0.61,-0.6,3.776,,53.15,HPH,-1.02233,0.0500837,0.000644786,1.03692 beta-lactamase_39_K109T,beta-lactamase_39_109,TEM-1,beta-lactamase_39,P62593,1.03692,NO,109,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.734,-2.559,0.825,,0.787,G,A,2.34,2.21,7.243,,72.73,ABB,-1.63333,0.0495842,0.00462493,1.03692 PSD95pdz3_T387A,PSD95pdz3_387,PSD95pdz3,PSD95pdz3,P31016,1.03692,NO,387,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.391,-2.534,1.143,5.20757,,,,,18.8043,,,,HPH,-1.49533,0.0758425,0.000167911,1.03692 beta-lactamase_156_R273F,beta-lactamase_156_273,TEM-1,beta-lactamase_156,P62593,1.03694,NO,273,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.314,-4.428,2.114,,0.564,H,A,1.2,1.57,20.248,20.248,73.78,ABP,-1.841,0.111618,0.0077952,1.03694 beta-lactamase_39_W208D,beta-lactamase_39_208,TEM-1,beta-lactamase_39,P62593,1.03695,NO,208,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-0.818,-4.144,3.326,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.0495842,0.00126609,1.03695 PSD95pdz3_R354C,PSD95pdz3_354,PSD95pdz3,PSD95pdz3,P31016,1.03695,NO,354,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.582,-4.769,3.187,6.21887,,,,,23.7791,,,,HBB,-1.44833,0.0758425,0.000650924,1.03695 beta-lactamase_0_S51D,beta-lactamase_0_51,TEM-1,beta-lactamase_0,P62593,1.03696,NO,51,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.526,-2.756,1.23,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.0500837,0.00504821,1.03696 beta-lactamase_E102D,beta-lactamase_102,TEM-1,beta-lactamase,P62593,1.03696,NO,102,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.118,-2.118,0,6.36157,0.722,S,B,1.5,1.82,1.336,,73.08,HAH,-1.581,0.221079,0.00486633,1.03696 beta-lactamase_T193V,beta-lactamase_193,TEM-1,beta-lactamase,P62593,1.03696,NO,193,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.914,-2.673,0.759,5.67952,0.439,H,a,0.3,0.33,1.863,,63.99,HPO,-1.52133,0.221079,0.00482669,1.03696 beta-lactamase_T193Y,beta-lactamase_193,TEM-1,beta-lactamase,P62593,1.03696,NO,193,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.914,-3.989,2.075,5.67952,0.439,H,a,0.3,0.33,1.863,,63.99,HPO,-1.52133,0.221079,0.00482669,1.03696 PSD95pdz3_S371R,PSD95pdz3_371,PSD95pdz3,PSD95pdz3,P31016,1.03699,NO,371,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.86,-3.485,1.625,5.19744,,,,,17.1117,3.854,,87.71,HPB,-1.598,0.0758425,0.000847873,1.03699 PSD95pdz3_T385K,PSD95pdz3_385,PSD95pdz3,PSD95pdz3,P31016,1.03701,NO,385,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.533,-3.138,1.605,5.57157,,,,,23.6871,4.527,,87.71,PPH,-1.56567,0.0758425,0.000545119,1.03701 kka2_1:8_V16L,kka2_1:8_16,Kka2,kka2_1:8,P00552,1.03706,NO,16,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-3.087,-2.643,-0.444,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.100394,0.00694011,1.03706 kka2_1:8_V16L,kka2_1:8_16,Kka2,kka2_1:8,P00552,1.03706,NO,16,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-3.087,-2.643,-0.444,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.100394,0.00694011,1.03706 PSD95pdz3_E352S,PSD95pdz3_352,PSD95pdz3,PSD95pdz3,P31016,1.03706,NO,352,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.587,-2.841,1.254,5.49659,,,,,24.2,2.525,,86.88,OAH,-1.314,0.0758425,0.000892231,1.03706 beta-lactamase_625_T138I,beta-lactamase_625_138,TEM-1,beta-lactamase_625,P62593,1.03707,NO,138,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.506,-4.099,1.593,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.213352,0.00487868,1.03707 beta-lactamase_0_E26L,beta-lactamase_0_26,TEM-1,beta-lactamase_0,P62593,1.03708,NO,26,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.454,-2.726,0.272,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.0500837,0.00297948,1.03708 beta-lactamase_0_I261V,beta-lactamase_0_261,TEM-1,beta-lactamase_0,P62593,1.03708,NO,261,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.0500837,0.0123091,1.03708 beta-lactamase_156_A215V,beta-lactamase_156_215,TEM-1,beta-lactamase_156,P62593,1.03708,NO,215,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.503,-3.464,1.961,,,,a,0.46,-0.93,3.583,,74.48,HHO,-1.42633,0.111618,0.00544007,1.03708 kka2_1:4_C31F,kka2_1:4_31,Kka2,kka2_1:4,P00552,1.03711,NO,31,C,F,CF,Special,Hydrophobic,5.07,3.32051,-1.74949,205,121,165,44,108.5,189.9,81.4,-2.246,-4.376,2.13,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.168804,0.00681582,1.03711 kka2_1:8_E231S,kka2_1:8_231,Kka2,kka2_1:8,P00552,1.03713,NO,231,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.002,-3.227,1.225,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.100394,0.00732383,1.03713 kka2_1:8_E231S,kka2_1:8_231,Kka2,kka2_1:8,P00552,1.03713,NO,231,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.002,-3.227,1.225,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.100394,0.00732383,1.03713 beta-lactamase_39_T186Y,beta-lactamase_39_186,TEM-1,beta-lactamase_39,P62593,1.03715,NO,186,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.522,-4.364,1.842,,0.396,H,A,0.22,-0.28,0.515,,77.62,HPP,-1.77633,0.0495842,0.00485034,1.03715 kka2_1:4_D183Q,kka2_1:4_183,Kka2,kka2_1:4,P00552,1.03715,NO,183,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.204,-2.915,1.711,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.168804,0.00426304,1.03715 beta-lactamase_156_E108S,beta-lactamase_156_108,TEM-1,beta-lactamase_156,P62593,1.03717,NO,108,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.46,-2.354,0.894,,0.572,G,A,1.04,1.87,8.602,8.602,72.73,PAB,-1.437,0.111618,0.00413372,1.03717 beta-lactamase_39_T131M,beta-lactamase_39_131,TEM-1,beta-lactamase_39,P62593,1.03719,NO,131,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.328,-4.602,3.274,,,H,A,0.22,-0.69,3.306,,67.48,PPH,-1.00867,0.0495842,0.00345886,1.03719 kka2_1:4_T85C,kka2_1:4_85,Kka2,kka2_1:4,P00552,1.03719,NO,85,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.165,-5.123,2.958,,0.576,E,B,0.22,1.39,1.853,,71.59,HPA,-2.10133,0.168804,0.00634493,1.03719 beta-lactamase_0_D207C,beta-lactamase_0_207,TEM-1,beta-lactamase_0,P62593,1.03723,NO,207,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.064,-5.19,3.126,,0.409,H,A,0.75,0.12,5.277,,77.62,HAH,-1.77033,0.0500837,0.00592942,1.03723 beta-lactamase_0_Q86A,beta-lactamase_0_86,TEM-1,beta-lactamase_0,P62593,1.03723,NO,86,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.4,-2.601,0.201,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.0500837,0.00450027,1.03723 PSD95pdz3_A382C,PSD95pdz3_382,PSD95pdz3,PSD95pdz3,P31016,1.03723,NO,382,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.307,-4.094,2.787,5.30282,,,,,22.472,,,,PHO,-1.24167,0.0758425,0.000249256,1.03723 beta-lactamase_39_H110R,beta-lactamase_39_110,TEM-1,beta-lactamase_39,P62593,1.03726,NO,110,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-1.706,-2.008,0.302,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.0495842,0.00441499,1.03726 beta-lactamase_0_I244E,beta-lactamase_0_244,TEM-1,beta-lactamase_0,P62593,1.03727,NO,244,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.555,-3.795,2.24,,,E,B,0.48,-0.84,1.241,,77.62,OHH,-1.385,0.0500837,0.00605379,1.03727 beta-lactamase_0_R81L,beta-lactamase_0_81,TEM-1,beta-lactamase_0,P62593,1.03731,NO,81,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.466,-2.766,1.3,,0.218,H,A,1.2,1.66,0.332,,50,PBH,-1.60667,0.0500837,0.00499763,1.03731 PSD95pdz3_K355P,PSD95pdz3_355,PSD95pdz3,PSD95pdz3,P31016,1.03731,NO,355,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.416,-3.336,1.92,5.56865,,,,,17.2556,,,,BBO,-1.33533,0.0758425,0.00063703,1.03731 kka2_1:8_V46K,kka2_1:8_46,Kka2,kka2_1:8,P00552,1.03734,NO,46,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-2.62,-3.127,0.507,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.100394,0.00631301,1.03734 kka2_1:8_V46K,kka2_1:8_46,Kka2,kka2_1:8,P00552,1.03734,NO,46,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-2.62,-3.127,0.507,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.100394,0.00631301,1.03734 beta-lactamase_39_L223Q,beta-lactamase_39_223,TEM-1,beta-lactamase_39,P62593,1.03736,NO,223,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.055,-4.184,3.129,,0.27,,B,0.55,0.09,1.511,,74.48,HHO,-1.35033,0.0495842,0.00372793,1.03736 beta-lactamase_625_E26I,beta-lactamase_625_26,TEM-1,beta-lactamase_625,P62593,1.03736,NO,26,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.454,-3.782,1.328,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.213352,0.00297948,1.03736 beta-lactamase_39_E87S,beta-lactamase_39_87,TEM-1,beta-lactamase_39,P62593,1.0374,NO,87,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.421,-3.382,1.961,,0.048,,B,1.04,0.92,15.231,15.231,64.69,PAP,-1.969,0.0495842,0.00337888,1.0374 beta-lactamase_39_E26T,beta-lactamase_39_26,TEM-1,beta-lactamase_39,P62593,1.03741,NO,26,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.454,-2.753,0.299,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.0495842,0.00297948,1.03741 beta-lactamase_39_F228L,beta-lactamase_39_228,TEM-1,beta-lactamase_39,P62593,1.03743,NO,228,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-2.342,-3.312,0.97,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.0495842,0.0046669,1.03743 beta-lactamase_39_G226W,beta-lactamase_39_226,TEM-1,beta-lactamase_39,P62593,1.03743,NO,226,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.461,-5.464,4.003,,0.701,T,l,0.29,-0.25,23.034,23.034,74.48,HOH,-1.42933,0.0495842,0.00665294,1.03743 beta-lactamase_39_K190Y,beta-lactamase_39_190,TEM-1,beta-lactamase_39,P62593,1.03743,NO,190,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.994,-4.283,2.289,,0.371,H,A,2.34,0.16,1.513,,77.62,BBH,-1.64167,0.0495842,0.00574527,1.03743 gb1_T275L,gb1_275,gb1,gb1,P06654,1.03744,NO,275,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.727,-2.224,0.497,,,,,,,0.511,,35.71,HPB,-1.637,0.177985,0.00606618,1.03744 gb1_V255T,gb1_255,gb1,gb1,P06654,1.03744,NO,255,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-3.127,-2.168,-0.959,,,,,,,1.323,,45.54,BHH,-2.03867,0.177985,0.00408354,1.03744 beta-lactamase_0_L73V,beta-lactamase_0_73,TEM-1,beta-lactamase_0,P62593,1.03745,NO,73,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.507,-2.286,0.779,,,H,A,0.55,-0.64,0.877,,67.83,HHH,-1.487,0.0500837,0.00488983,1.03745 kka2_1:2_H106N,kka2_1:2_106,Kka2,kka2_1:2,P00552,1.03746,NO,106,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-3.13,-3.028,-0.102,,1.065,.,a,0.17,-0.95,2.53,,71.59,PBH,-2.10433,0.295029,0.00730778,1.03746 PSD95pdz3_F337H,PSD95pdz3_337,PSD95pdz3,PSD95pdz3,P31016,1.03747,NO,337,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.524,-4.137,2.613,5.22838,,,,,13.4936,,,,HHH,-1.59467,0.0758425,0.000875287,1.03747 beta-lactamase_0_G226E,beta-lactamase_0_226,TEM-1,beta-lactamase_0,P62593,1.03748,NO,226,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.461,-2.776,1.315,,0.701,T,l,0.29,-0.25,23.034,23.034,74.48,HOH,-1.42933,0.0500837,0.00665294,1.03748 beta-lactamase_156_T138Q,beta-lactamase_156_138,TEM-1,beta-lactamase_156,P62593,1.03748,NO,138,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.506,-3.82,1.314,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.111618,0.00487868,1.03748 kka2_1:8_E231L,kka2_1:8_231,Kka2,kka2_1:8,P00552,1.03748,NO,231,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.002,-3.642,1.64,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.100394,0.00732383,1.03748 kka2_1:8_E231L,kka2_1:8_231,Kka2,kka2_1:8,P00552,1.03748,NO,231,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.002,-3.642,1.64,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.100394,0.00732383,1.03748 kka2_1:2_A79C,kka2_1:2_79,Kka2,kka2_1:2,P00552,1.03751,NO,79,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.368,-5.212,2.844,,0.563,.,B,0.46,-0.43,0.475,,71.59,HHH,-1.752,0.295029,0.00664821,1.03751 beta-lactamase_625_V29F,beta-lactamase_625_29,TEM-1,beta-lactamase_625,P62593,1.03756,NO,29,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-2.856,-4.364,1.508,,0.733,H,A,0.44,-0.78,1.931,,93.01,HHB,-2.24733,0.213352,0.00318969,1.03756 kka2_1:8_C31W,kka2_1:8_31,Kka2,kka2_1:8,P00552,1.03756,NO,31,C,W,CW,Special,Hydrophobic,5.07,5.89,0.82,215,121,204,83,108.5,227.8,119.3,-2.246,-5.453,3.207,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.100394,0.00681582,1.03756 kka2_1:8_C31W,kka2_1:8_31,Kka2,kka2_1:8,P00552,1.03756,NO,31,C,W,CW,Special,Hydrophobic,5.07,5.89,0.82,215,121,204,83,108.5,227.8,119.3,-2.246,-5.453,3.207,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.100394,0.00681582,1.03756 kka2_1:8_E231Q,kka2_1:8_231,Kka2,kka2_1:8,P00552,1.0376,NO,231,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.002,-3.771,1.769,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.100394,0.00732383,1.0376 kka2_1:8_E231Q,kka2_1:8_231,Kka2,kka2_1:8,P00552,1.0376,NO,231,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.002,-3.771,1.769,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.100394,0.00732383,1.0376 beta-lactamase_2500_T186D,beta-lactamase_2500_186,TEM-1,beta-lactamase_2500,P62593,1.03764,NO,186,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.522,-2.935,0.413,,0.396,H,A,0.22,-0.28,2.144,,77.62,HPP,-1.77633,0.361275,0.00485034,1.03764 kka2_1:2_H139D,kka2_1:2_139,Kka2,kka2_1:2,P00552,1.03765,NO,139,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-2.809,-3.251,0.442,,0.471,H,A,0.87,0.68,13.912,13.912,63.64,BBB,-2.22,0.295029,0.00734779,1.03765 PSD95pdz3_V362A,PSD95pdz3_362,PSD95pdz3,PSD95pdz3,P31016,1.03766,NO,362,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.465,-2.534,1.069,4.99436,,,,,19.6443,,,,PHP,-1.46467,0.0758425,0.000538527,1.03766 beta-lactamase_156_F149M,beta-lactamase_156_149,TEM-1,beta-lactamase_156,P62593,1.03767,NO,149,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.299,-4.454,3.155,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.111618,0.00418462,1.03767 beta-lactamase_39_E87N,beta-lactamase_39_87,TEM-1,beta-lactamase_39,P62593,1.03769,NO,87,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.421,-3.684,2.263,,0.048,,B,1.04,0.92,15.231,15.231,64.69,PAP,-1.969,0.0495842,0.00337888,1.03769 beta-lactamase_39_T187N,beta-lactamase_39_187,TEM-1,beta-lactamase_39,P62593,1.03769,NO,187,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.401,-2.373,0.972,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.0495842,0.00491782,1.03769 gb1_I232F,gb1_232,gb1,gb1,P06654,1.0377,NO,232,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-2.175,-3.802,1.627,,,,,,,0.766,,44.87,HHH,-2.152,0.177985,0.00580459,1.0377 beta-lactamase_0_E62H,beta-lactamase_0_62,TEM-1,beta-lactamase_0,P62593,1.03771,NO,62,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.193,-4.429,3.236,,0.342,S,B,1.04,-0.3,5.784,,73.08,AAB,-1.417,0.0500837,0.00264802,1.03771 beta-lactamase_R118H,beta-lactamase_118,TEM-1,beta-lactamase,P62593,1.03771,NO,118,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.413,-4.71,2.297,5.8227,0.457,H,A,0.68,1.39,2.144,,77.62,HBA,-1.785,0.221079,0.00538794,1.03771 kka2_1:4_S251G,kka2_1:4_251,Kka2,kka2_1:4,P00552,1.03771,NO,251,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.636,-2.736,0.1,,0.712,H,A,0.77,-0.25,,,71.59,APP,-2.09367,0.168804,0.0138916,1.03771 beta-lactamase_625_H110T,beta-lactamase_625_110,TEM-1,beta-lactamase_625,P62593,1.03773,NO,110,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-1.706,-3.697,1.991,,0.341,G,a,0.17,1.08,31.31,31.31,64.69,BBH,-1.73333,0.213352,0.00441499,1.03773 beta-lactamase_39_N130Q,beta-lactamase_39_130,TEM-1,beta-lactamase_39,P62593,1.03777,NO,130,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-0.798,-3.674,2.876,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.0495842,0.000683376,1.03777 PSD95pdz3_I388C,PSD95pdz3_388,PSD95pdz3,PSD95pdz3,P31016,1.03781,NO,388,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.63,-4.319,2.689,5.17282,,,,,16.0025,,,,PHH,-1.54967,0.0758425,0.000151216,1.03781 PSD95pdz3_T385H,PSD95pdz3_385,PSD95pdz3,PSD95pdz3,P31016,1.03782,NO,385,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.533,-4.361,2.828,5.57157,,,,,23.6871,4.527,,87.71,PPH,-1.56567,0.0758425,0.000545119,1.03782 beta-lactamase_39_F149Y,beta-lactamase_39_149,TEM-1,beta-lactamase_39,P62593,1.03784,NO,149,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.299,-1.705,0.406,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.0495842,0.00418462,1.03784 beta-lactamase_39_P143Q,beta-lactamase_39_143,TEM-1,beta-lactamase_39,P62593,1.03784,NO,143,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.967,-4.024,3.057,,0.075,H,A,0.52,-0.37,0.976,,66.78,OOB,-1.354,0.0495842,0.00114551,1.03784 PSD95pdz3_D366V,PSD95pdz3_366,PSD95pdz3,PSD95pdz3,P31016,1.03785,NO,366,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.264,-3.435,2.171,5.55684,,,,,20.2375,,,,HAH,-1.401,0.0758425,0.000481272,1.03785 beta-lactamase_0_S221Q,beta-lactamase_0_221,TEM-1,beta-lactamase_0,P62593,1.03786,NO,221,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.754,-3.871,2.117,,0.624,H,A,0.27,-0.2,2.914,,74.48,BPH,-1.59967,0.0500837,0.0046094,1.03786 beta-lactamase_39_R63M,beta-lactamase_39_63,TEM-1,beta-lactamase_39,P62593,1.03789,NO,63,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-0.943,-4.402,3.459,,0.218,,B,1.2,-0.31,0.326,,44.06,ABH,-0.992333,0.0495842,0.00126938,1.03789 kka2_1:4_R18Q,kka2_1:4_18,Kka2,kka2_1:4,P00552,1.03789,NO,18,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.055,-2.59,0.535,,0.474,T,A,1.2,0.54,8.405,8.405,71.59,ABH,-1.821,0.168804,0.00724065,1.03789 beta-lactamase_39_E108H,beta-lactamase_39_108,TEM-1,beta-lactamase_39,P62593,1.0379,NO,108,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.46,-4.53,3.07,,0.572,G,A,1.04,1.87,20.151,20.151,72.73,PAB,-1.437,0.0495842,0.00413372,1.0379 beta-lactamase_T261M,beta-lactamase_261,TEM-1,beta-lactamase,P62593,1.03792,NO,261,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.88,-2.387,-0.493,5.65483,0.014,E,B,0.53,-0.39,2.449,,77.62,HPP,-1.771,0.221079,0.0123091,1.03792 beta-lactamase_39_G141F,beta-lactamase_39_141,TEM-1,beta-lactamase_39,P62593,1.03795,NO,141,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.828,-4.352,3.524,,0.575,T,l,0.29,-0.28,0.722,,64.69,HOO,-1.08933,0.0495842,0.0012419,1.03795 beta-lactamase_39_R81F,beta-lactamase_39_81,TEM-1,beta-lactamase_39,P62593,1.03795,NO,81,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.466,-4.359,2.893,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.0495842,0.00499763,1.03795 beta-lactamase_39_I285T,beta-lactamase_39_285,TEM-1,beta-lactamase_39,P62593,1.03798,NO,285,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.0495842,0.101555,1.03798 beta-lactamase_39_T198C,beta-lactamase_39_198,TEM-1,beta-lactamase_39,P62593,1.03798,NO,198,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.168,-4.902,2.734,,0.489,,B,0.22,-0.13,3.614,,73.78,HPH,-1.98767,0.0495842,0.004311,1.03798 beta-lactamase_39_V106K,beta-lactamase_39_106,TEM-1,beta-lactamase_39,P62593,1.03799,NO,106,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.218,-3.831,2.613,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.0495842,0.00304168,1.03799 beta-lactamase_39_I93L,beta-lactamase_39_93,TEM-1,beta-lactamase_39,P62593,1.038,NO,93,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.401,-2.05,0.649,,0.128,E,B,0.48,0.44,1.757,,67.83,BHB,-1.873,0.0495842,0.00527066,1.038 kka2_1:8_W236F,kka2_1:8_236,Kka2,kka2_1:8,P00552,1.038,NO,236,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-1.363,-2.652,1.289,,0.303,H,A,1.51,-0.76,1.87,,48.48,AHH,-1.81267,0.100394,0.0088796,1.038 kka2_1:8_W236F,kka2_1:8_236,Kka2,kka2_1:8,P00552,1.038,NO,236,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-1.363,-2.652,1.289,,0.303,H,A,1.51,-0.76,1.87,,48.48,AHH,-1.81267,0.100394,0.0088796,1.038 beta-lactamase_0_I206G,beta-lactamase_0_206,TEM-1,beta-lactamase_0,P62593,1.03801,NO,206,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-2.429,-2.667,0.238,,0.173,H,A,0.48,-0.34,3.411,,77.62,HHA,-1.805,0.0500837,0.00528934,1.03801 E1_Ubiquitin_L73W,E1_Ubiquitin_73,Uba1,E1_Ubiquitin,P0CG63,1.03802,NO,73,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.039,-4.915,3.876,,0.518,,B,1.3,1,,,,BHB,-1.175,0.18783,0.00111236,1.03802 PSD95pdz3_K355N,PSD95pdz3_355,PSD95pdz3,PSD95pdz3,P31016,1.03802,NO,355,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.416,-3.13,1.714,5.56865,,,,,17.2556,,,,BBO,-1.33533,0.0758425,0.00063703,1.03802 PSD95pdz3_A378T,PSD95pdz3_378,PSD95pdz3,PSD95pdz3,P31016,1.03806,NO,378,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.307,-2.878,1.571,4.86582,,,,,14.576,,,,HHH,-1.509,0.0758425,0.000313169,1.03806 beta-lactamase_R118W,beta-lactamase_118,TEM-1,beta-lactamase,P62593,1.03807,NO,118,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.413,-5.439,3.026,5.8227,0.457,H,A,0.68,1.39,2.144,,77.62,HBA,-1.785,0.221079,0.00538794,1.03807 beta-lactamase_39_F228G,beta-lactamase_39_228,TEM-1,beta-lactamase_39,P62593,1.03809,NO,228,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-2.342,-3.572,1.23,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.0495842,0.0046669,1.03809 PSD95pdz3_F325C,PSD95pdz3_325,PSD95pdz3,PSD95pdz3,P31016,1.03812,NO,325,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.524,-4.544,3.02,5.50654,,,,,12.7236,,,,OHP,-1.314,0.0758425,0.00102273,1.03812 beta-lactamase_39_I93E,beta-lactamase_39_93,TEM-1,beta-lactamase_39,P62593,1.03817,NO,93,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.401,-3.886,2.485,,0.128,E,B,0.48,0.44,1.757,,67.83,BHB,-1.873,0.0495842,0.00527066,1.03817 beta-lactamase_0_S283A,beta-lactamase_0_283,TEM-1,beta-lactamase_0,P62593,1.03818,NO,283,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.0500837,0.0429138,1.03818 beta-lactamase_625_R275I,beta-lactamase_625_275,TEM-1,beta-lactamase_625,P62593,1.03818,NO,275,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.397,-4.133,2.736,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.213352,0.0141984,1.03818 kka2_1:4_L241M,kka2_1:4_241,Kka2,kka2_1:4,P00552,1.03819,NO,241,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.158,-4.084,2.926,,0.08,H,A,0.55,-0.82,1.598,,63.26,HHH,-1.58533,0.168804,0.0117299,1.03819 PSD95pdz3_S350C,PSD95pdz3_350,PSD95pdz3,PSD95pdz3,P31016,1.0382,NO,350,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.519,-4.319,2.8,4.97629,,,,,25.01,,,,HPO,-1.29133,0.0758425,0.000704883,1.0382 gb1_N234W,gb1_234,gb1,gb1,P06654,1.03821,NO,234,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-2.055,-5.222,3.167,,,,,,,1.235,,45.54,HPO,-2.05067,0.177985,0.00242189,1.03821 kka2_1:2_E235Q,kka2_1:2_235,Kka2,kka2_1:2,P00552,1.03821,NO,235,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.955,-2.458,0.503,,0.631,H,A,1.04,0.12,26.048,26.048,65.53,OAH,-2.07267,0.295029,0.0102806,1.03821 beta-lactamase_0_L205M,beta-lactamase_0_205,TEM-1,beta-lactamase_0,P62593,1.03822,NO,205,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.922,-3.889,2.967,,,H,A,0.55,-0.46,1.065,,42.31,PHH,-1.57767,0.0500837,0.00255802,1.03822 beta-lactamase_0_S57H,beta-lactamase_0_57,TEM-1,beta-lactamase_0,P62593,1.03823,NO,57,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.918,-3.329,1.411,,0.352,E,B,0.27,-0.18,1.454,,72.73,APH,-2.29167,0.0500837,0.00492804,1.03823 beta-lactamase_39_I285V,beta-lactamase_39_285,TEM-1,beta-lactamase_39,P62593,1.03825,NO,285,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.0495842,0.101555,1.03825 PSD95pdz3_A343L,PSD95pdz3_343,PSD95pdz3,PSD95pdz3,P31016,1.03825,NO,343,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.307,-2.815,1.508,5.585,,,,,14.728,,,,HHO,-1.22067,0.0758425,0.000798084,1.03825 beta-lactamase_Y260F,beta-lactamase_260,TEM-1,beta-lactamase,P62593,1.03828,NO,260,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-1.101,-1.921,0.82,5.50878,,E,B,0.73,-1.04,0.865,,60.49,HHP,-1.83433,0.221079,0.00471757,1.03828 kka2_1:4_A64R,kka2_1:4_64,Kka2,kka2_1:4,P00552,1.03829,NO,64,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.496,-4.086,2.59,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.168804,0.00705578,1.03829 beta-lactamase_39_I244L,beta-lactamase_39_244,TEM-1,beta-lactamase_39,P62593,1.03832,NO,244,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.555,-2.697,1.142,,,E,B,0.48,-0.84,1.325,,77.62,OHH,-1.385,0.0495842,0.00605379,1.03832 gb1_A274P,gb1_274,gb1,gb1,P06654,1.03833,NO,274,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.728,-3.52,1.792,,,,,,,4.162,4.162,11.83,AHP,-1.81767,0.177985,0.0068419,1.03833 PSD95pdz3_K355T,PSD95pdz3_355,PSD95pdz3,PSD95pdz3,P31016,1.03834,NO,355,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.416,-3.103,1.687,5.56865,,,,,17.2556,,,,BBO,-1.33533,0.0758425,0.00063703,1.03834 PSD95pdz3_Q358T,PSD95pdz3_358,PSD95pdz3,PSD95pdz3,P31016,1.03837,NO,358,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-1.699,-3.103,1.404,5.21282,,,,,14.8844,,,,APH,-1.531,0.0758425,0.000594893,1.03837 kka2_1:2_R122T,kka2_1:2_122,Kka2,kka2_1:2,P00552,1.03838,NO,122,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.175,-2.452,0.277,,0.487,H,A,1.2,0.26,16.436,16.436,71.59,BBH,-1.53833,0.295029,0.00736512,1.03838 kka2_1:8_F256V,kka2_1:8_256,Kka2,kka2_1:8,P00552,1.03838,NO,256,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.49,-3.528,2.038,,,H,A,1.62,-0.78,1.713,,53.03,HHH,-1.423,0.100394,0.0132841,1.03838 kka2_1:8_F256V,kka2_1:8_256,Kka2,kka2_1:8,P00552,1.03838,NO,256,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.49,-3.528,2.038,,,H,A,1.62,-0.78,1.713,,53.03,HHH,-1.423,0.100394,0.0132841,1.03838 beta-lactamase_0_N50G,beta-lactamase_0_50,TEM-1,beta-lactamase_0,P62593,1.0384,NO,50,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-2.979,-2.053,-0.926,,0.912,T,A,0.61,1.24,9.874,9.874,77.62,HPP,-2.134,0.0500837,0.0047211,1.0384 beta-lactamase_L19F,beta-lactamase_19,TEM-1,beta-lactamase,P62593,1.03842,NO,19,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.682,-2.455,0.773,,,,,,,4.261,,93.01,OHO,-1.894,0.221079,0.00215974,1.03842 beta-lactamase_L19Y,beta-lactamase_19,TEM-1,beta-lactamase,P62593,1.03842,NO,19,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.682,-3.844,2.162,,,,,,,4.261,,93.01,OHO,-1.894,0.221079,0.00215974,1.03842 kka2_1:8_L158H,kka2_1:8_158,Kka2,kka2_1:8,P00552,1.03842,NO,158,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.947,-4.683,2.736,,0.095,.,B,0.55,0.77,1.607,,63.64,AHA,-1.25333,0.100394,0.00529068,1.03842 kka2_1:8_L158H,kka2_1:8_158,Kka2,kka2_1:8,P00552,1.03842,NO,158,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.947,-4.683,2.736,,0.095,.,B,0.55,0.77,1.607,,63.64,AHA,-1.25333,0.100394,0.00529068,1.03842 PSD95pdz3_L360W,PSD95pdz3_360,PSD95pdz3,PSD95pdz3,P31016,1.03845,NO,360,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.431,-4.778,3.347,5.09284,,,,,14.2425,1.419,,86.88,HHP,-1.52667,0.0758425,0.000770471,1.03845 beta-lactamase_625_I45Y,beta-lactamase_625_45,TEM-1,beta-lactamase_625,P62593,1.03846,NO,45,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-2.421,-2.914,0.493,,,E,B,0.48,-0.3,3.642,,77.62,HHA,-2.30267,0.213352,0.00452842,1.03846 gb1_Q228I,gb1_228,gb1,gb1,P06654,1.03846,NO,228,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,,,,,,,,,,,,,OPH,-1.282,0.177985,0.00391043,1.03846 beta-lactamase_39_E166Y,beta-lactamase_39_166,TEM-1,beta-lactamase_39,P62593,1.03849,NO,166,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.756,-4.36,2.604,,0.508,G,A,1.04,1.05,17.227,17.227,73.08,OAH,-1.42233,0.0495842,0.00512989,1.03849 beta-lactamase_39_E145F,beta-lactamase_39_145,TEM-1,beta-lactamase_39,P62593,1.0385,NO,145,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.357,-4.373,2.016,,0.545,H,A,1.04,0.79,1.199,,77.62,BAH,-2.069,0.0495842,0.00553285,1.0385 beta-lactamase_39_I93V,beta-lactamase_39_93,TEM-1,beta-lactamase_39,P62593,1.0385,NO,93,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.401,-1.692,0.291,,0.128,E,B,0.48,0.44,1.757,,67.83,BHB,-1.873,0.0495842,0.00527066,1.0385 beta-lactamase_K30C,beta-lactamase_30,TEM-1,beta-lactamase,P62593,1.03852,NO,30,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-2.307,-5.006,2.699,5.30605,0.142,H,A,1.82,-0.65,2.434,,93.01,HBH,-2.32833,0.221079,0.00448593,1.03852 kka2_1:8_C31K,kka2_1:8_31,Kka2,kka2_1:8,P00552,1.03852,NO,31,C,K,CK,Special,PositiveCharge,5.07,9.74,4.67,202,121,146,25,108.5,168.6,60.1,-2.246,-3.377,1.131,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.100394,0.00681582,1.03852 kka2_1:8_C31K,kka2_1:8_31,Kka2,kka2_1:8,P00552,1.03852,NO,31,C,K,CK,Special,PositiveCharge,5.07,9.74,4.67,202,121,146,25,108.5,168.6,60.1,-2.246,-3.377,1.131,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.100394,0.00681582,1.03852 beta-lactamase_156_F70I,beta-lactamase_156_70,TEM-1,beta-lactamase_156,P62593,1.03853,NO,70,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.169,-3.353,2.184,,,H,A,0.58,-1.34,1.918,,63.99,PHB,-0.980667,0.111618,0.00193499,1.03853 PSD95pdz3_D366N,PSD95pdz3_366,PSD95pdz3,PSD95pdz3,P31016,1.03853,NO,366,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.264,-2.905,1.641,5.55684,,,,,20.2375,,,,HAH,-1.401,0.0758425,0.000481272,1.03853 beta-lactamase_39_R91W,beta-lactamase_39_91,TEM-1,beta-lactamase_39,P62593,1.03855,NO,91,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.392,-5.388,3.996,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.0495842,0.00380226,1.03855 beta-lactamase_39_I244D,beta-lactamase_39_244,TEM-1,beta-lactamase_39,P62593,1.03856,NO,244,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.555,-3.943,2.388,,,E,B,0.48,-0.84,1.325,,77.62,OHH,-1.385,0.0495842,0.00605379,1.03856 kka2_1:8_G10D,kka2_1:8_10,Kka2,kka2_1:8,P00552,1.03857,NO,10,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.921,-2.473,0.552,,,,,,,1.862,,71.59,HOP,-2.10733,0.100394,0.00289233,1.03857 kka2_1:8_G10D,kka2_1:8_10,Kka2,kka2_1:8,P00552,1.03857,NO,10,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.921,-2.473,0.552,,,,,,,1.862,,71.59,HOP,-2.10733,0.100394,0.00289233,1.03857 beta-lactamase_0_Q267K,beta-lactamase_0_267,TEM-1,beta-lactamase_0,P62593,1.03858,NO,267,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.0500837,0.0102128,1.03858 beta-lactamase_39_L197M,beta-lactamase_39_197,TEM-1,beta-lactamase_39,P62593,1.03861,NO,197,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.853,-3.888,3.035,,0.007,S,B,0.55,0.33,1.559,,60.14,HHP,-1.833,0.0495842,0.00144602,1.03861 beta-lactamase_156_I93A,beta-lactamase_156_93,TEM-1,beta-lactamase_156,P62593,1.03866,NO,93,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.401,-3.13,1.729,,0.128,E,B,0.48,0.44,1.524,,67.83,BHB,-1.873,0.111618,0.00527066,1.03866 beta-lactamase_39_A170Q,beta-lactamase_39_170,TEM-1,beta-lactamase_39,P62593,1.03868,NO,170,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.237,-4.086,2.849,,0.126,,L,0.46,-0.35,3.7,,64.69,AHH,-1.63267,0.0495842,0.00431903,1.03868 beta-lactamase_39_R220G,beta-lactamase_39_220,TEM-1,beta-lactamase_39,P62593,1.03868,NO,220,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-0.942,-3.321,2.379,,0.295,I,A,1.2,-0.76,1.596,,74.48,HBP,-1.33633,0.0495842,0.00232421,1.03868 beta-lactamase_156_Q86F,beta-lactamase_156_86,TEM-1,beta-lactamase_156,P62593,1.0387,NO,86,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.4,-4.354,1.954,,0.696,S,A,0.64,2.38,27.704,27.704,77.62,OPA,-1.61067,0.111618,0.00450027,1.0387 kka2_1:8_L53H,kka2_1:8_53,Kka2,kka2_1:8,P00552,1.0387,NO,53,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-2.681,-4.842,2.161,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.100394,0.00671168,1.0387 kka2_1:8_L53H,kka2_1:8_53,Kka2,kka2_1:8,P00552,1.0387,NO,53,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-2.681,-4.842,2.161,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.100394,0.00671168,1.0387 beta-lactamase_39_E108S,beta-lactamase_39_108,TEM-1,beta-lactamase_39,P62593,1.03871,NO,108,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.46,-2.354,0.894,,0.572,G,A,1.04,1.87,20.151,20.151,72.73,PAB,-1.437,0.0495842,0.00413372,1.03871 gb1_A274S,gb1_274,gb1,gb1,P06654,1.03871,NO,274,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.728,-2.936,1.208,,,,,,,4.162,4.162,11.83,AHP,-1.81767,0.177985,0.0068419,1.03871 beta-lactamase_0_P65K,beta-lactamase_0_65,TEM-1,beta-lactamase_0,P62593,1.03872,NO,65,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.894,-3.511,2.617,,0.098,E,B,0.52,-0.62,0.663,,40.56,HOH,-1.03233,0.0500837,0.00152776,1.03872 PSD95pdz3_S371L,PSD95pdz3_371,PSD95pdz3,PSD95pdz3,P31016,1.03873,NO,371,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.86,-2.994,1.134,5.19744,,,,,17.1117,3.854,,87.71,HPB,-1.598,0.0758425,0.000847873,1.03873 PSD95pdz3_V365S,PSD95pdz3_365,PSD95pdz3,PSD95pdz3,P31016,1.03873,NO,365,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.592,-3.061,1.469,5.03791,,,,,18.9657,2.364,,81.35,OHA,-1.288,0.0758425,0.000649764,1.03873 beta-lactamase_625_H110K,beta-lactamase_625_110,TEM-1,beta-lactamase_625,P62593,1.03874,NO,110,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-1.706,-2.755,1.049,,0.341,G,a,0.17,1.08,31.31,31.31,64.69,BBH,-1.73333,0.213352,0.00441499,1.03874 kka2_1:8_A229F,kka2_1:8_229,Kka2,kka2_1:8,P00552,1.03879,NO,229,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.739,-4.384,2.645,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.100394,0.00942138,1.03879 kka2_1:8_A229F,kka2_1:8_229,Kka2,kka2_1:8,P00552,1.03879,NO,229,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.739,-4.384,2.645,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.100394,0.00942138,1.03879 beta-lactamase_156_S283Y,beta-lactamase_156_283,TEM-1,beta-lactamase_156,P62593,1.0388,NO,283,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.111618,0.0429138,1.0388 beta-lactamase_39_H110E,beta-lactamase_39_110,TEM-1,beta-lactamase_39,P62593,1.0388,NO,110,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-1.706,-2.766,1.06,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.0495842,0.00441499,1.0388 beta-lactamase_L199V,beta-lactamase_199,TEM-1,beta-lactamase,P62593,1.03884,NO,199,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-2.942,-2.773,-0.169,5.57712,0.832,H,A,0.82,0.42,15.302,15.302,77.62,PHH,-2.32933,0.221079,0.0048649,1.03884 gb1_T275H,gb1_275,gb1,gb1,P06654,1.03884,NO,275,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.727,-4.533,2.806,,,,,,,0.511,,35.71,HPB,-1.637,0.177985,0.00606618,1.03884 kka2_1:4_A255R,kka2_1:4_255,Kka2,kka2_1:4,P00552,1.03884,NO,255,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.715,-2.777,1.062,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.168804,0.0126809,1.03884 PSD95pdz3_L360N,PSD95pdz3_360,PSD95pdz3,PSD95pdz3,P31016,1.03884,NO,360,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.431,-3.804,2.373,5.09284,,,,,14.2425,1.419,,86.88,HHP,-1.52667,0.0758425,0.000770471,1.03884 kka2_1:8_A71E,kka2_1:8_71,Kka2,kka2_1:8,P00552,1.03886,NO,71,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.824,-2.798,0.974,,0.553,H,A,0.46,0.08,18.64,18.64,64.39,HHP,-1.74033,0.100394,0.00727707,1.03886 kka2_1:8_A71E,kka2_1:8_71,Kka2,kka2_1:8,P00552,1.03886,NO,71,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.824,-2.798,0.974,,0.553,H,A,0.46,0.08,18.64,18.64,64.39,HHP,-1.74033,0.100394,0.00727707,1.03886 beta-lactamase_39_K32F,beta-lactamase_39_32,TEM-1,beta-lactamase_39,P62593,1.03887,NO,32,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.984,-4.328,2.344,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.0495842,0.00401283,1.03887 beta-lactamase_0_V157R,beta-lactamase_0_157,TEM-1,beta-lactamase_0,P62593,1.03889,NO,157,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.751,-3.07,1.319,,0.308,S,a,0.44,-0.75,3.106,,69.58,BHP,-2.00767,0.0500837,0.00506849,1.03889 beta-lactamase_39_T107F,beta-lactamase_39_107,TEM-1,beta-lactamase_39,P62593,1.03891,NO,107,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.117,-4.119,3.002,,,G,A,0.22,-0.06,2.686,,67.83,HPA,-1.265,0.0495842,0.00239347,1.03891 kka2_1:8_P167R,kka2_1:8_167,Kka2,kka2_1:8,P00552,1.03892,NO,167,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-2.403,-4.046,1.643,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.100394,0.00543203,1.03892 kka2_1:8_P167R,kka2_1:8_167,Kka2,kka2_1:8,P00552,1.03892,NO,167,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-2.403,-4.046,1.643,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.100394,0.00543203,1.03892 beta-lactamase_39_F58G,beta-lactamase_39_58,TEM-1,beta-lactamase_39,P62593,1.03893,NO,58,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-2.914,-3.566,0.652,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.0495842,0.00523369,1.03893 kka2_1:1_L7P,kka2_1:1_7,Kka2,kka2_1:1,P00552,1.03894,NO,7,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.926,-3.817,1.891,,,,,,,18.934,18.934,71.59,OHB,-2.12333,0.520039,0.00269456,1.03894 kka2_1:4_L92M,kka2_1:4_92,Kka2,kka2_1:4,P00552,1.03896,NO,92,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.893,-2.898,2.005,,0.007,E,B,0.55,-0.19,1.447,,63.26,HHH,-0.962,0.168804,0.00307177,1.03896 gb1_T270W,gb1_270,gb1,gb1,P06654,1.03897,NO,270,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-3.15,-4.937,1.787,,,,,,,1.326,,45.54,HPH,-1.843,0.177985,0.00223707,1.03897 gb1_V255S,gb1_255,gb1,gb1,P06654,1.03897,NO,255,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-3.127,-3.058,-0.069,,,,,,,1.323,,45.54,BHH,-2.03867,0.177985,0.00408354,1.03897 beta-lactamase_625_E272L,beta-lactamase_625_272,TEM-1,beta-lactamase_625,P62593,1.03899,NO,272,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.213352,0.00545371,1.03899 kka2_1:8_C31L,kka2_1:8_31,Kka2,kka2_1:8,P00552,1.03899,NO,31,C,L,CL,Special,Hydrophobic,5.07,9.7088,4.6388,198,121,131,10,108.5,166.7,58.2,-2.246,-3.487,1.241,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.100394,0.00681582,1.03899 kka2_1:8_C31L,kka2_1:8_31,Kka2,kka2_1:8,P00552,1.03899,NO,31,C,L,CL,Special,Hydrophobic,5.07,9.7088,4.6388,198,121,131,10,108.5,166.7,58.2,-2.246,-3.487,1.241,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.100394,0.00681582,1.03899 beta-lactamase_39_T187F,beta-lactamase_39_187,TEM-1,beta-lactamase_39,P62593,1.039,NO,187,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.401,-4.141,2.74,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.0495842,0.00491782,1.039 beta-lactamase_2500_K190A,beta-lactamase_2500_190,TEM-1,beta-lactamase_2500,P62593,1.03901,NO,190,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.994,-2.146,0.152,,0.371,H,A,2.34,0.16,29.753,29.753,77.62,BBH,-1.64167,0.361275,0.00574527,1.03901 kka2_1:4_I246A,kka2_1:4_246,Kka2,kka2_1:4,P00552,1.03901,NO,246,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-2.008,-2.246,0.238,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.168804,0.0139479,1.03901 kka2_1:4_W91G,kka2_1:4_91,Kka2,kka2_1:4,P00552,1.03901,NO,91,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-1.178,-3.516,2.338,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.168804,0.00358653,1.03901 beta-lactamase_39_E108C,beta-lactamase_39_108,TEM-1,beta-lactamase_39,P62593,1.03902,NO,108,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.46,-5.208,3.748,,0.572,G,A,1.04,1.87,20.151,20.151,72.73,PAB,-1.437,0.0495842,0.00413372,1.03902 PSD95pdz3_K355C,PSD95pdz3_355,PSD95pdz3,PSD95pdz3,P31016,1.03902,NO,355,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.416,-4.769,3.353,5.56865,,,,,17.2556,,,,BBO,-1.33533,0.0758425,0.00063703,1.03902 PSD95pdz3_P346N,PSD95pdz3_346,PSD95pdz3,PSD95pdz3,P31016,1.03902,NO,346,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.236,-3.58,2.344,5.02406,,,,,14.6629,,,,OOH,-1.18367,0.0758425,0.000758563,1.03902 beta-lactamase_2500_S283N,beta-lactamase_2500_283,TEM-1,beta-lactamase_2500,P62593,1.03906,NO,283,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.361275,0.0429138,1.03906 PSD95pdz3_N381A,PSD95pdz3_381,PSD95pdz3,PSD95pdz3,P31016,1.03906,NO,381,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-1.41,-2.984,1.574,5.66057,,,,,28.2162,,,,BPH,-1.37767,0.0758425,0.000265374,1.03906 gb1_Q228S,gb1_228,gb1,gb1,P06654,1.03909,NO,228,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,,,,,,,,,,,,,OPH,-1.282,0.177985,0.00391043,1.03909 beta-lactamase_625_T138Q,beta-lactamase_625_138,TEM-1,beta-lactamase_625,P62593,1.0391,NO,138,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.506,-3.82,1.314,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.213352,0.00487868,1.0391 beta-lactamase_39_L197K,beta-lactamase_39_197,TEM-1,beta-lactamase_39,P62593,1.03911,NO,197,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.853,-3.679,2.826,,0.007,S,B,0.55,0.33,1.559,,60.14,HHP,-1.833,0.0495842,0.00144602,1.03911 beta-lactamase_D129D,beta-lactamase_129,TEM-1,beta-lactamase,P62593,1.03911,NO,129,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.816,-0.816,,4.84204,,,B,1.33,-0.69,0.548,,34.97,PAP,-0.818,0.221079,0.00109178,1.03911 beta-lactamase_D250Q,beta-lactamase_250,TEM-1,beta-lactamase,P62593,1.03911,NO,250,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.335,-3.938,1.603,5.72026,0.89,T,L,0.23,1.53,24.737,24.737,66.08,OAO,-1.85133,0.221079,0.00550899,1.03911 beta-lactamase_L19S,beta-lactamase_19,TEM-1,beta-lactamase,P62593,1.03911,NO,19,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.682,-3.483,1.801,,,,,,,4.261,,93.01,OHO,-1.894,0.221079,0.00215974,1.03911 beta-lactamase_39_R59E,beta-lactamase_39_59,TEM-1,beta-lactamase_39,P62593,1.03912,NO,59,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.345,-3.322,1.977,,0.329,S,L,1.2,-0.09,1.806,,73.08,HBO,-2.24267,0.0495842,0.00318082,1.03912 kka2_1:4_R145S,kka2_1:4_145,Kka2,kka2_1:4,P00552,1.03912,NO,145,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.804,-2.769,0.965,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.168804,0.00846663,1.03912 beta-lactamase_625_G216F,beta-lactamase_625_216,TEM-1,beta-lactamase_625,P62593,1.03919,NO,216,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.477,-4.417,2.94,,0.437,I,A,0.29,-0.58,1.718,,74.48,HOO,-1.68067,0.213352,0.00639568,1.03919 gb1_V255L,gb1_255,gb1,gb1,P06654,1.03922,NO,255,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-3.127,-3.106,-0.021,,,,,,,1.323,,45.54,BHH,-2.03867,0.177985,0.00408354,1.03922 beta-lactamase_0_V260A,beta-lactamase_0_260,TEM-1,beta-lactamase_0,P62593,1.03923,NO,260,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.0500837,0.00471757,1.03923 beta-lactamase_625_P25Q,beta-lactamase_625_25,TEM-1,beta-lactamase_625,P62593,1.03924,NO,25,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.526,-2.522,0.996,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.213352,0.00347571,1.03924 beta-lactamase_625_V106Q,beta-lactamase_625_106,TEM-1,beta-lactamase_625,P62593,1.03928,NO,106,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.218,-4.248,3.03,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.213352,0.00304168,1.03928 beta-lactamase_39_A183K,beta-lactamase_39_183,TEM-1,beta-lactamase_39,P62593,1.03929,NO,183,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.231,-3.508,2.277,,0.155,H,A,0.46,-0.91,1.237,,77.62,HHH,-1.53367,0.0495842,0.00296631,1.03929 kka2_1:4_R145E,kka2_1:4_145,Kka2,kka2_1:4,P00552,1.03929,NO,145,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.804,-2.289,0.485,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.168804,0.00846663,1.03929 PSD95pdz3_E334N,PSD95pdz3_334,PSD95pdz3,PSD95pdz3,P31016,1.03929,NO,334,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.404,-3.13,1.726,5.60175,,,,,53.09,,,,OAO,-1.14,0.0758425,0.000912998,1.03929 beta-lactamase_39_L49I,beta-lactamase_39_49,TEM-1,beta-lactamase_39,P62593,1.03932,NO,49,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.897,-3.523,1.626,,0.131,T,A,0.55,0.04,13.838,13.838,64.69,AHP,-1.99233,0.0495842,0.00401477,1.03932 kka2_1:8_P98H,kka2_1:8_98,Kka2,kka2_1:8,P00552,1.03934,NO,98,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.526,-4.763,3.237,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.100394,0.00622754,1.03934 kka2_1:8_P98H,kka2_1:8_98,Kka2,kka2_1:8,P00552,1.03934,NO,98,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.526,-4.763,3.237,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.100394,0.00622754,1.03934 beta-lactamase_156_R239Y,beta-lactamase_156_239,TEM-1,beta-lactamase_156,P62593,1.03939,NO,239,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.111618,0.00213852,1.03939 PSD95pdz3_D332H,PSD95pdz3_332,PSD95pdz3,PSD95pdz3,P31016,1.0394,NO,332,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.264,-4.137,2.873,6.09878,,,,,48.762,,,,AAO,-1.22533,0.0758425,0.000937818,1.0394 beta-lactamase_G39E,beta-lactamase_39,TEM-1,beta-lactamase,P62593,1.03941,NO,39,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.864,-2.833,0.969,5.35574,0.701,T,L,0.23,0.47,29.926,29.926,77.62,HOH,-1.53633,0.221079,0.00487611,1.03941 kka2_1:8_E86R,kka2_1:8_86,Kka2,kka2_1:8,P00552,1.03943,NO,86,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.86,-3.888,2.028,,0.369,,B,1.52,1.92,,,63.26,PAH,-1.98067,0.100394,0.00642858,1.03943 kka2_1:8_E86R,kka2_1:8_86,Kka2,kka2_1:8,P00552,1.03943,NO,86,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.86,-3.888,2.028,,0.369,,B,1.52,1.92,,,63.26,PAH,-1.98067,0.100394,0.00642858,1.03943 beta-lactamase_0_R63L,beta-lactamase_0_63,TEM-1,beta-lactamase_0,P62593,1.03946,NO,63,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-0.943,-2.476,1.533,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.0500837,0.00126938,1.03946 beta-lactamase_39_E195T,beta-lactamase_39_195,TEM-1,beta-lactamase_39,P62593,1.03946,NO,195,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.186,-2.956,0.77,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.0495842,0.00496565,1.03946 kka2_1:8_D238Y,kka2_1:8_238,Kka2,kka2_1:8,P00552,1.03947,NO,238,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.83,-4.447,1.617,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.100394,0.0113863,1.03947 kka2_1:8_D238Y,kka2_1:8_238,Kka2,kka2_1:8,P00552,1.03947,NO,238,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.83,-4.447,1.617,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.100394,0.0113863,1.03947 beta-lactamase_39_E195Y,beta-lactamase_39_195,TEM-1,beta-lactamase_39,P62593,1.03949,NO,195,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.186,-4.374,2.188,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.0495842,0.00496565,1.03949 beta-lactamase_39_S241C,beta-lactamase_39_241,TEM-1,beta-lactamase_39,P62593,1.03952,NO,241,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.0495842,0.00452736,1.03952 PSD95pdz3_G319K,PSD95pdz3_319,PSD95pdz3,PSD95pdz3,P31016,1.03952,NO,319,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.008,-3.364,2.356,4.95387,,,,,18.8725,,,,BOP,-1.36967,0.0758425,0.00109317,1.03952 beta-lactamase_156_D212G,beta-lactamase_156_212,TEM-1,beta-lactamase_156,P62593,1.03953,NO,212,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.624,-2.198,0.574,,0.037,,b,0.75,-0.58,20.222,20.222,74.48,HAB,-1.77667,0.111618,0.00644302,1.03953 beta-lactamase_A15C,beta-lactamase_15,TEM-1,beta-lactamase,P62593,1.03954,NO,15,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.654,-4.652,2.998,,,,,,,31.998,31.998,93.01,HHH,-2.10833,0.221079,0.00248966,1.03954 kka2_1:8_V153W,kka2_1:8_153,Kka2,kka2_1:8,P00552,1.03954,NO,153,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.092,-5.429,4.337,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.100394,0.00501119,1.03954 kka2_1:8_V153W,kka2_1:8_153,Kka2,kka2_1:8,P00552,1.03954,NO,153,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.092,-5.429,4.337,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.100394,0.00501119,1.03954 beta-lactamase_0_L223C,beta-lactamase_0_223,TEM-1,beta-lactamase_0,P62593,1.03955,NO,223,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.055,-4.721,3.666,,0.27,,B,0.55,0.09,1.633,,74.48,HHO,-1.35033,0.0500837,0.00372793,1.03955 beta-lactamase_39_R59Y,beta-lactamase_39_59,TEM-1,beta-lactamase_39,P62593,1.03955,NO,59,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.345,-4.267,2.922,,0.329,S,L,1.2,-0.09,1.806,,73.08,HBO,-2.24267,0.0495842,0.00318082,1.03955 beta-lactamase_625_V106L,beta-lactamase_625_106,TEM-1,beta-lactamase_625,P62593,1.03956,NO,106,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.218,-2.154,0.936,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.213352,0.00304168,1.03956 kka2_1:2_F206W,kka2_1:2_206,Kka2,kka2_1:2,P00552,1.03956,NO,206,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.349,-4.609,3.26,,0.006,E,B,0.58,-1.21,0.978,,63.64,OHH,-1.04,0.295029,0.00936868,1.03956 beta-lactamase_39_H110G,beta-lactamase_39_110,TEM-1,beta-lactamase_39,P62593,1.03957,NO,110,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-1.706,-3.573,1.867,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.0495842,0.00441499,1.03957 beta-lactamase_0_P255M,beta-lactamase_0_255,TEM-1,beta-lactamase_0,P62593,1.03959,NO,255,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.0500837,0.00499612,1.03959 beta-lactamase_39_Q267Y,beta-lactamase_39_267,TEM-1,beta-lactamase_39,P62593,1.03959,NO,267,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.0495842,0.0102128,1.03959 beta-lactamase_E210E,beta-lactamase_210,TEM-1,beta-lactamase,P62593,1.03962,NO,210,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.319,-2.319,,5.7398,0.476,H,A,0.52,0.75,1.555,,77.62,HAH,-1.88567,0.221079,0.00663582,1.03962 beta-lactamase_39_F228V,beta-lactamase_39_228,TEM-1,beta-lactamase_39,P62593,1.03963,NO,228,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-2.342,-2.889,0.547,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.0495842,0.0046669,1.03963 beta-lactamase_39_T27G,beta-lactamase_39_27,TEM-1,beta-lactamase_39,P62593,1.03963,NO,27,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.905,-3.36,1.455,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.0495842,0.00306559,1.03963 beta-lactamase_156_E26V,beta-lactamase_156_26,TEM-1,beta-lactamase_156,P62593,1.03965,NO,26,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.454,-2.776,0.322,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.111618,0.00297948,1.03965 beta-lactamase_N152D,beta-lactamase_152,TEM-1,beta-lactamase,P62593,1.03966,NO,152,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-2.757,-3.573,0.816,5.98571,0.863,H,A,0.09,0.92,2.061,,77.62,BPH,-2.97,0.221079,0.00471429,1.03966 kka2_1:2_L53E,kka2_1:2_53,Kka2,kka2_1:2,P00552,1.03966,NO,53,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-2.681,-2.451,-0.23,,0.569,E,B,0.55,0.8,19.536,19.536,71.59,AHP,-2.47433,0.295029,0.00671168,1.03966 beta-lactamase_39_E46I,beta-lactamase_39_46,TEM-1,beta-lactamase_39,P62593,1.03967,NO,46,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.94,-2.064,0.124,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.0495842,0.00427568,1.03967 WW_domain_G176G,WW_domain_176,Yap65,WW_domain,P46937,1.03967,NO,176,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.235,-1.235,0,6.33142,,,,,,2.71,,78.57,HOH,-1.35467,0.153962,0.00288552,1.03967 beta-lactamase_39_F58N,beta-lactamase_39_58,TEM-1,beta-lactamase_39,P62593,1.03968,NO,58,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-2.914,-3.795,0.881,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.0495842,0.00523369,1.03968 PSD95pdz3_S320H,PSD95pdz3_320,PSD95pdz3,PSD95pdz3,P31016,1.03969,NO,320,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.519,-4.137,2.618,5.81757,,,,,21.4517,,,,OPP,-1.306,0.0758425,0.00108158,1.03969 beta-lactamase_0_S96K,beta-lactamase_0_96,TEM-1,beta-lactamase_0,P62593,1.0397,NO,96,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.27,-2.895,0.625,,0.368,,b,0.27,0.39,2.516,,73.78,HPP,-2.019,0.0500837,0.00551835,1.0397 beta-lactamase_156_L223V,beta-lactamase_156_223,TEM-1,beta-lactamase_156,P62593,1.0397,NO,223,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.055,-2.195,1.14,,0.27,,B,0.55,0.09,1.511,,74.48,HHO,-1.35033,0.111618,0.00372793,1.0397 beta-lactamase_156_G253M,beta-lactamase_156_253,TEM-1,beta-lactamase_156,P62593,1.03971,NO,253,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.111618,0.00786358,1.03971 kka2_1:2_T146N,kka2_1:2_146,Kka2,kka2_1:2,P00552,1.03971,NO,146,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.978,-3.146,0.168,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.295029,0.00606474,1.03971 gb1_T275Y,gb1_275,gb1,gb1,P06654,1.03972,NO,275,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.727,-4.081,2.354,,,,,,,0.511,,35.71,HPB,-1.637,0.177985,0.00606618,1.03972 kka2_1:8_A110P,kka2_1:8_110,Kka2,kka2_1:8,P00552,1.03975,NO,110,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.064,-3.089,1.025,,0.175,H,A,1.04,-1.19,11.413,11.413,71.59,OHA,-1.91867,0.100394,0.00759851,1.03975 kka2_1:8_A110P,kka2_1:8_110,Kka2,kka2_1:8,P00552,1.03975,NO,110,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.064,-3.089,1.025,,0.175,H,A,1.04,-1.19,11.413,11.413,71.59,OHA,-1.91867,0.100394,0.00759851,1.03975 beta-lactamase_156_V29C,beta-lactamase_156_29,TEM-1,beta-lactamase_156,P62593,1.03979,NO,29,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-2.856,-5.117,2.261,,0.733,H,A,0.44,-0.78,3.685,,93.01,HHB,-2.24733,0.111618,0.00318969,1.03979 beta-lactamase_T112K,beta-lactamase_112,TEM-1,beta-lactamase,P62593,1.03979,NO,112,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.186,-2.704,0.518,6.47162,0.921,T,A,0.77,1.06,2.04,,73.78,HPA,-1.925,0.221079,0.00531334,1.03979 E1_Ubiquitin_K48Y,E1_Ubiquitin_48,Uba1,E1_Ubiquitin,P0CG63,1.03979,NO,48,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.219,-4.033,2.814,,0.132,E,B,,-0.28,,,,OBO,-1.109,0.18783,0.00100363,1.03979 E1_Ubiquitin_L71D,E1_Ubiquitin_71,Uba1,E1_Ubiquitin,P0CG63,1.03979,NO,71,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.039,-3.961,2.922,,0.591,E,B,,-0.69,,,,BHB,-1.19433,0.18783,0.00148349,1.03979 E1_Ubiquitin_Q41F,E1_Ubiquitin_41,Uba1,E1_Ubiquitin,P0CG63,1.03979,NO,41,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-1.25,-4.109,2.859,,0.017,E,B,,-0.98,,,,PPB,-1.344,0.18783,0.00215097,1.03979 E1_Ubiquitin_Q41T,E1_Ubiquitin_41,Uba1,E1_Ubiquitin,P0CG63,1.03979,NO,41,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-1.25,-3.239,1.989,,0.017,E,B,,-0.98,,,,PPB,-1.344,0.18783,0.00215097,1.03979 E1_Ubiquitin_R42N,E1_Ubiquitin_42,Uba1,E1_Ubiquitin,P0CG63,1.03979,NO,42,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.302,-3.318,2.016,,0.244,E,B,,-0.54,,,,PBH,-1.24667,0.18783,0.00224033,1.03979 beta-lactamase_39_R92P,beta-lactamase_39_92,TEM-1,beta-lactamase_39,P62593,1.03981,NO,92,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.718,-3.033,1.315,,0.479,E,B,1.2,1.36,0.389,,65.38,BBH,-1.50367,0.0495842,0.00429626,1.03981 beta-lactamase_0_A215F,beta-lactamase_0_215,TEM-1,beta-lactamase_0,P62593,1.03982,NO,215,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.503,-4.278,2.775,,,,a,0.46,-0.93,0.494,,74.48,HHO,-1.42633,0.0500837,0.00544007,1.03982 beta-lactamase_0_E238H,beta-lactamase_0_238,TEM-1,beta-lactamase_0,P62593,1.03983,NO,238,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.0500837,0.00743256,1.03983 gb1_D272V,gb1_272,gb1,gb1,P06654,1.03985,NO,272,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.457,-3.558,2.101,,,,,,,0.234,,11.83,HAA,-1.54533,0.177985,0.00218257,1.03985 kka2_1:4_R239W,kka2_1:4_239,Kka2,kka2_1:4,P00552,1.03985,NO,239,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.949,-5.592,2.643,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.168804,0.00835326,1.03985 beta-lactamase_156_T138N,beta-lactamase_156_138,TEM-1,beta-lactamase_156,P62593,1.03986,NO,138,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.506,-2.961,0.455,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.111618,0.00487868,1.03986 beta-lactamase_2500_K190R,beta-lactamase_2500_190,TEM-1,beta-lactamase_2500,P62593,1.03987,NO,190,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.994,-2.302,0.308,,0.371,H,A,2.34,0.16,29.753,29.753,77.62,BBH,-1.64167,0.361275,0.00574527,1.03987 beta-lactamase_39_F58I,beta-lactamase_39_58,TEM-1,beta-lactamase_39,P62593,1.03987,NO,58,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-2.914,-3.971,1.057,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.0495842,0.00523369,1.03987 beta-lactamase_N152H,beta-lactamase_152,TEM-1,beta-lactamase,P62593,1.03988,NO,152,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-2.757,-3.372,0.615,5.98571,0.863,H,A,0.09,0.92,2.061,,77.62,BPH,-2.97,0.221079,0.00471429,1.03988 PSD95pdz3_N363M,PSD95pdz3_363,PSD95pdz3,PSD95pdz3,P31016,1.03991,NO,363,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-1.41,-4.387,2.977,5.23349,,,,,20.7037,,,,HPO,-1.29433,0.0758425,0.000524014,1.03991 beta-lactamase_0_N98I,beta-lactamase_0_98,TEM-1,beta-lactamase_0,P62593,1.03992,NO,98,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-2.973,-4.064,1.091,,0.963,G,A,0.61,1.35,14.853,14.853,77.62,PPA,-2.07867,0.0500837,0.00505389,1.03992 beta-lactamase_39_R118E,beta-lactamase_39_118,TEM-1,beta-lactamase_39,P62593,1.03992,NO,118,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.413,-2.454,0.041,,0.457,H,A,1.2,1.39,3.961,,77.62,HBA,-1.785,0.0495842,0.00538794,1.03992 beta-lactamase_39_R220E,beta-lactamase_39_220,TEM-1,beta-lactamase_39,P62593,1.03993,NO,220,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-0.942,-3.264,2.322,,0.295,I,A,1.2,-0.76,1.596,,74.48,HBP,-1.33633,0.0495842,0.00232421,1.03993 kka2_1:4_T85M,kka2_1:4_85,Kka2,kka2_1:4,P00552,1.03994,NO,85,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.165,-4.675,2.51,,0.576,E,B,0.22,1.39,1.853,,71.59,HPA,-2.10133,0.168804,0.00634493,1.03994 beta-lactamase_625_K190L,beta-lactamase_625_190,TEM-1,beta-lactamase_625,P62593,1.04001,NO,190,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.994,-3.527,1.533,,0.371,H,A,2.34,0.16,29.753,29.753,77.62,BBH,-1.64167,0.213352,0.00574527,1.04001 beta-lactamase_0_H24E,beta-lactamase_0_24,TEM-1,beta-lactamase_0,P62593,1.04004,NO,24,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-2.481,-3.284,0.803,,,,,,,2.708,,93.01,OBO,-2.0035,0.0500837,0.00238894,1.04004 beta-lactamase_39_V157W,beta-lactamase_39_157,TEM-1,beta-lactamase_39,P62593,1.04005,NO,157,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.751,-5.264,3.513,,0.308,S,a,0.44,-0.75,10.364,10.364,69.58,BHP,-2.00767,0.0495842,0.00506849,1.04005 PSD95pdz3_N381K,PSD95pdz3_381,PSD95pdz3,PSD95pdz3,P31016,1.04005,NO,381,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-1.41,-2.914,1.504,5.66057,,,,,28.2162,,,,BPH,-1.37767,0.0758425,0.000265374,1.04005 beta-lactamase_625_K190V,beta-lactamase_625_190,TEM-1,beta-lactamase_625,P62593,1.04008,NO,190,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.994,-2.992,0.998,,0.371,H,A,2.34,0.16,29.753,29.753,77.62,BBH,-1.64167,0.213352,0.00574527,1.04008 gb1_Q258K,gb1_258,gb1,gb1,P06654,1.0401,NO,258,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.095,-3.146,1.051,,,,,,,0.86,,37.28,BPH,-1.88333,0.177985,0.00437595,1.0401 beta-lactamase_2500_P25K,beta-lactamase_2500_25,TEM-1,beta-lactamase_2500,P62593,1.04013,NO,25,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.526,-3.426,1.9,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.361275,0.00347571,1.04013 kka2_1:2_Q252K,kka2_1:2_252,Kka2,kka2_1:2,P00552,1.04014,NO,252,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.63,-2.767,0.137,,0.906,H,A,0.64,0.35,5.613,,92.05,PPB,-2.20733,0.295029,0.0121001,1.04014 beta-lactamase_0_E61H,beta-lactamase_0_61,TEM-1,beta-lactamase_0,P62593,1.04015,NO,61,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.115,-4.518,2.403,,0.775,T,a,1.04,1.29,34.763,34.763,77.62,OAA,-1.92567,0.0500837,0.00440955,1.04015 beta-lactamase_39_P105D,beta-lactamase_39_105,TEM-1,beta-lactamase_39,P62593,1.04015,NO,105,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.813,-3.466,2.653,,0.226,T,A,0.52,0.8,1.222,,63.29,POH,-1.01533,0.0495842,0.0011981,1.04015 kka2_1:4_A71I,kka2_1:4_71,Kka2,kka2_1:4,P00552,1.04017,NO,71,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.824,-4.1,2.276,,0.553,H,A,0.46,0.08,5.76,,64.39,HHP,-1.74033,0.168804,0.00727707,1.04017 beta-lactamase_2500_A222K,beta-lactamase_2500_222,TEM-1,beta-lactamase_2500,P62593,1.04018,NO,222,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.103,-3.694,1.591,,0.233,H,A,0.46,-0.25,0.379,,77.62,PHH,-1.63733,0.361275,0.00466094,1.04018 beta-lactamase_39_A222K,beta-lactamase_39_222,TEM-1,beta-lactamase_39,P62593,1.04021,NO,222,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.103,-3.694,1.591,,0.233,H,A,0.46,-0.25,1.448,,77.62,PHH,-1.63733,0.0495842,0.00466094,1.04021 beta-lactamase_39_P60N,beta-lactamase_39_60,TEM-1,beta-lactamase_39,P62593,1.04024,NO,60,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-2.469,-3.804,1.335,,0.256,T,A,0.52,-0.56,21.37,21.37,77.62,BOA,-1.97633,0.0495842,0.00521318,1.04024 beta-lactamase_0_E56R,beta-lactamase_0_56,TEM-1,beta-lactamase_0,P62593,1.04026,NO,56,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.043,-3.679,1.636,,0.198,E,B,1.04,0.31,1.491,,72.73,HAP,-1.94033,0.0500837,0.00238534,1.04026 beta-lactamase_0_T112A,beta-lactamase_0_112,TEM-1,beta-lactamase_0,P62593,1.04029,NO,112,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.186,-1.933,-0.253,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.0500837,0.00531334,1.04029 beta-lactamase_0_H24G,beta-lactamase_0_24,TEM-1,beta-lactamase_0,P62593,1.0403,NO,24,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-2.481,-2.499,0.018,,,,,,,2.708,,93.01,OBO,-2.0035,0.0500837,0.00238894,1.0403 Ubiquitin_E51D,Ubiquitin_51,Uba1,Ubiquitin,P0CG48,1.04032,NO,51,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.534,-2.175,0.641,5.36711,0.545,,B,,0.72,,,,HAA,-1.357,0.205827,0.000868134,1.04032 Ubiquitin_E64Q,Ubiquitin_64,Uba1,Ubiquitin,P0CG48,1.04032,NO,64,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.763,-2.788,1.025,5.084,0.54,T,l,,0.79,,,,BAP,-1.64433,0.205827,0.000817406,1.04032 Ubiquitin_G53E,Ubiquitin_53,Uba1,Ubiquitin,P0CG48,1.04032,NO,53,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.544,-3.571,2.027,5.32628,0.805,T,A,,-0.23,,,,AOB,-1.67033,0.205827,0.000662865,1.04032 Ubiquitin_G53K,Ubiquitin_53,Uba1,Ubiquitin,P0CG48,1.04032,NO,53,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.544,-2.876,1.332,5.32628,0.805,T,A,,-0.23,,,,AOB,-1.67033,0.205827,0.000662865,1.04032 Ubiquitin_G53N,Ubiquitin_53,Uba1,Ubiquitin,P0CG48,1.04032,NO,53,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.544,-2.86,1.316,5.32628,0.805,T,A,,-0.23,,,,AOB,-1.67033,0.205827,0.000662865,1.04032 Ubiquitin_G53Q,Ubiquitin_53,Uba1,Ubiquitin,P0CG48,1.04032,NO,53,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.544,-4.049,2.505,5.32628,0.805,T,A,,-0.23,,,,AOB,-1.67033,0.205827,0.000662865,1.04032 kka2_1:8_D134H,kka2_1:8_134,Kka2,kka2_1:8,P00552,1.04034,NO,134,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.969,-4.532,3.563,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.100394,0.00270812,1.04034 kka2_1:8_D134H,kka2_1:8_134,Kka2,kka2_1:8,P00552,1.04034,NO,134,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.969,-4.532,3.563,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.100394,0.00270812,1.04034 PSD95pdz3_I389G,PSD95pdz3_389,PSD95pdz3,PSD95pdz3,P31016,1.04035,NO,389,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.628,-3.489,1.861,5.15116,,,,,14.8038,1.498,,87.71,HHH,-1.52167,0.0758425,0.00148097,1.04035 PSD95pdz3_Q384Y,PSD95pdz3_384,PSD95pdz3,PSD95pdz3,P31016,1.04035,NO,384,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-1.699,-3.619,1.92,5.49339,,,,,23.54,,,,OPP,-1.41333,0.0758425,0.000216736,1.04035 beta-lactamase_0_D113S,beta-lactamase_0_113,TEM-1,beta-lactamase_0,P62593,1.04036,NO,113,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.829,-2.84,1.011,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.0500837,0.00474112,1.04036 beta-lactamase_A182L,beta-lactamase_182,TEM-1,beta-lactamase,P62593,1.04037,NO,182,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.777,-3.486,1.709,4.98609,0.136,H,A,0.52,-0.66,2.032,,93.01,OHH,-1.27367,0.221079,0.00559099,1.04037 beta-lactamase_L199C,beta-lactamase_199,TEM-1,beta-lactamase,P62593,1.04037,NO,199,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-2.942,-5.078,2.136,5.57712,0.832,H,A,0.82,0.42,15.302,15.302,77.62,PHH,-2.32933,0.221079,0.0048649,1.04037 beta-lactamase_0_F64T,beta-lactamase_0_64,TEM-1,beta-lactamase_0,P62593,1.04039,NO,64,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-0.841,-3.646,2.805,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.0500837,0.000947691,1.04039 kka2_1:4_P179H,kka2_1:4_179,Kka2,kka2_1:4,P00552,1.0404,NO,179,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.974,-4.803,3.829,,0.113,,B,0.52,0.69,10.913,10.913,56.06,HOA,-2.19867,0.168804,0.00298346,1.0404 kka2_1:2_E182Q,kka2_1:2_182,Kka2,kka2_1:2,P00552,1.04041,NO,182,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.516,-2.606,1.09,,0.326,,B,1.52,0.75,14.547,14.547,65.53,OAA,-1.806,0.295029,0.00641548,1.04041 kka2_1:8_E142G,kka2_1:8_142,Kka2,kka2_1:8,P00552,1.04046,NO,142,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.221,-2.713,0.492,,0.471,H,A,1.04,0.85,2.655,,65.53,HAB,-2.08033,0.100394,0.00748883,1.04046 kka2_1:8_E142G,kka2_1:8_142,Kka2,kka2_1:8,P00552,1.04046,NO,142,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.221,-2.713,0.492,,0.471,H,A,1.04,0.85,2.655,,65.53,HAB,-2.08033,0.100394,0.00748883,1.04046 beta-lactamase_39_S80H,beta-lactamase_39_80,TEM-1,beta-lactamase_39,P62593,1.04047,NO,80,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.029,-3.359,1.33,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.0495842,0.00565569,1.04047 WW_domain_L190I,WW_domain_190,Yap65,WW_domain,P46937,1.04048,NO,190,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.404,-2.984,1.58,5.53598,,,,,,0.645,,56.55,HHP,-1.51833,0.153962,0.00249186,1.04048 kka2_1:8_V153P,kka2_1:8_153,Kka2,kka2_1:8,P00552,1.04049,NO,153,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.092,-4.027,2.935,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.100394,0.00501119,1.04049 kka2_1:8_V153P,kka2_1:8_153,Kka2,kka2_1:8,P00552,1.04049,NO,153,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.092,-4.027,2.935,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.100394,0.00501119,1.04049 beta-lactamase_39_F149V,beta-lactamase_39_149,TEM-1,beta-lactamase_39,P62593,1.0405,NO,149,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.299,-3.45,2.151,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.0495842,0.00418462,1.0405 PSD95pdz3_S371Q,PSD95pdz3_371,PSD95pdz3,PSD95pdz3,P31016,1.04054,NO,371,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.86,-3.58,1.72,5.19744,,,,,17.1117,3.854,,87.71,HPB,-1.598,0.0758425,0.000847873,1.04054 beta-lactamase_156_T138I,beta-lactamase_156_138,TEM-1,beta-lactamase_156,P62593,1.04056,NO,138,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.506,-4.099,1.593,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.111618,0.00487868,1.04056 kka2_1:2_D250Q,kka2_1:2_250,Kka2,kka2_1:2,P00552,1.04056,NO,250,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.015,-2.867,1.852,,0.274,.,b,0.75,-0.46,3.796,,51.89,OAP,-1.83933,0.295029,0.0177103,1.04056 beta-lactamase_625_R41E,beta-lactamase_625_41,TEM-1,beta-lactamase_625,P62593,1.04057,NO,41,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-0.942,-3.241,2.299,,0.321,E,B,1.2,-0.07,1.186,,65.03,HBH,-1.30267,0.213352,0.00123327,1.04057 kka2_1:2_A137Y,kka2_1:2_137,Kka2,kka2_1:2,P00552,1.04057,NO,137,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.156,-4.084,1.928,,0.029,H,A,0.46,0.34,1.323,,63.26,PHB,-2.559,0.295029,0.00515054,1.04057 WW_domain_D194I,WW_domain_194,Yap65,WW_domain,P46937,1.04057,NO,194,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.536,-2.53,0.994,5.95614,,,,,,1.948,,74.4,HAP,-1.78933,0.153962,0.00483742,1.04057 beta-lactamase_156_I285S,beta-lactamase_156_285,TEM-1,beta-lactamase_156,P62593,1.04062,NO,285,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.111618,0.101555,1.04062 beta-lactamase_156_E195M,beta-lactamase_156_195,TEM-1,beta-lactamase_156,P62593,1.04068,NO,195,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.186,-4.856,2.67,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.111618,0.00496565,1.04068 beta-lactamase_39_F58W,beta-lactamase_39_58,TEM-1,beta-lactamase_39,P62593,1.0407,NO,58,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-2.914,-2.275,-0.639,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.0495842,0.00523369,1.0407 beta-lactamase_39_K109C,beta-lactamase_39_109,TEM-1,beta-lactamase_39,P62593,1.04071,NO,109,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.734,-5.237,3.503,,0.787,G,A,2.34,2.21,7.243,,72.73,ABB,-1.63333,0.0495842,0.00462493,1.04071 beta-lactamase_0_A222G,beta-lactamase_0_222,TEM-1,beta-lactamase_0,P62593,1.04074,NO,222,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.103,-1.732,-0.371,,0.233,H,A,0.46,-0.25,2.015,,77.62,PHH,-1.63733,0.0500837,0.00466094,1.04074 beta-lactamase_39_E195I,beta-lactamase_39_195,TEM-1,beta-lactamase_39,P62593,1.04076,NO,195,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.186,-4.191,2.005,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.0495842,0.00496565,1.04076 Pab1_E161T,Pab1_161,Pab1,Pab1,P04147,1.04076,NO,161,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.474,-3.313,1.839,,0.663,T,a,,1.34,,,,AAP,-1.59067,0.175299,0.00276141,1.04076 beta-lactamase_156_D212R,beta-lactamase_156_212,TEM-1,beta-lactamase_156,P62593,1.04081,NO,212,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.624,-3.921,2.297,,0.037,,b,0.75,-0.58,20.222,20.222,74.48,HAB,-1.77667,0.111618,0.00644302,1.04081 beta-lactamase_0_R202G,beta-lactamase_0_202,TEM-1,beta-lactamase_0,P62593,1.04082,NO,202,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.292,-3.349,2.057,,0.188,H,A,1.2,0.62,7.016,,77.62,PBP,-1.54767,0.0500837,0.00321899,1.04082 kka2_1:8_D180C,kka2_1:8_180,Kka2,kka2_1:8,P00552,1.04082,NO,180,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.416,-5.213,2.797,,1.03,S,a,0.75,1.5,14.668,14.668,71.59,OAO,-2.02933,0.100394,0.00756412,1.04082 kka2_1:8_D180C,kka2_1:8_180,Kka2,kka2_1:8,P00552,1.04082,NO,180,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.416,-5.213,2.797,,1.03,S,a,0.75,1.5,14.668,14.668,71.59,OAO,-2.02933,0.100394,0.00756412,1.04082 beta-lactamase_625_I277L,beta-lactamase_625_277,TEM-1,beta-lactamase_625,P62593,1.04085,NO,277,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.213352,0.0169305,1.04085 beta-lactamase_39_G226Y,beta-lactamase_39_226,TEM-1,beta-lactamase_39,P62593,1.04087,NO,226,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.461,-4.462,3.001,,0.701,T,l,0.29,-0.25,23.034,23.034,74.48,HOH,-1.42933,0.0495842,0.00665294,1.04087 kka2_1:8_L93A,kka2_1:8_93,Kka2,kka2_1:8,P00552,1.04088,NO,93,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.815,-3.129,2.314,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.100394,0.00131498,1.04088 kka2_1:8_L93A,kka2_1:8_93,Kka2,kka2_1:8,P00552,1.04088,NO,93,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.815,-3.129,2.314,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.100394,0.00131498,1.04088 beta-lactamase_0_K232Y,beta-lactamase_0_232,TEM-1,beta-lactamase_0,P62593,1.04089,NO,232,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.012,-4.205,3.193,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.0500837,0.00313441,1.04089 beta-lactamase_39_S201F,beta-lactamase_39_201,TEM-1,beta-lactamase_39,P62593,1.04089,NO,201,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.183,-4.138,2.955,,0.064,H,A,0.27,-0.07,3.54,,64.69,HPB,-1.451,0.0495842,0.00198815,1.04089 kka2_1:8_K138H,kka2_1:8_138,Kka2,kka2_1:8,P00552,1.0409,NO,138,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-2.5,-3.509,1.009,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.100394,0.00628542,1.0409 kka2_1:8_K138H,kka2_1:8_138,Kka2,kka2_1:8,P00552,1.0409,NO,138,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-2.5,-3.509,1.009,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.100394,0.00628542,1.0409 beta-lactamase_625_V106G,beta-lactamase_625_106,TEM-1,beta-lactamase_625,P62593,1.04092,NO,106,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.218,-3.752,2.534,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.213352,0.00304168,1.04092 beta-lactamase_39_E87R,beta-lactamase_39_87,TEM-1,beta-lactamase_39,P62593,1.04094,NO,87,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.421,-3.739,2.318,,0.048,,B,1.04,0.92,15.231,15.231,64.69,PAP,-1.969,0.0495842,0.00337888,1.04094 beta-lactamase_F70F,beta-lactamase_70,TEM-1,beta-lactamase,P62593,1.04097,NO,70,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.169,-1.169,,5.42055,,H,A,1.1,-1.34,1.14,,63.99,PHB,-0.980667,0.221079,0.00193499,1.04097 beta-lactamase_S122E,beta-lactamase_122,TEM-1,beta-lactamase,P62593,1.04097,NO,122,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.406,-2.103,-0.303,4.87767,0.352,H,A,0.73,-0.54,1.581,,77.62,OPH,-1.39767,0.221079,0.00497825,1.04097 gb1_Q228G,gb1_228,gb1,gb1,P06654,1.04097,NO,228,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,,,,,,,,,,,,,OPH,-1.282,0.177985,0.00391043,1.04097 beta-lactamase_39_K254D,beta-lactamase_39_254,TEM-1,beta-lactamase_39,P62593,1.04099,NO,254,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.0495842,0.00369,1.04099 beta-lactamase_39_I140A,beta-lactamase_39_140,TEM-1,beta-lactamase_39,P62593,1.04102,NO,140,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.733,-3.145,1.412,,0.128,H,A,0.48,0.41,1.16,,73.08,PHO,-1.48733,0.0495842,0.00597777,1.04102 beta-lactamase_39_Y95Q,beta-lactamase_39_95,TEM-1,beta-lactamase_39,P62593,1.04102,NO,95,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-1.715,-4.267,2.552,,0.122,,b,0.21,-0.37,2.341,,77.62,BHP,-2.16167,0.0495842,0.00479449,1.04102 beta-lactamase_156_E108A,beta-lactamase_156_108,TEM-1,beta-lactamase_156,P62593,1.04103,NO,108,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.46,-2.613,1.153,,0.572,G,A,1.04,1.87,8.602,8.602,72.73,PAB,-1.437,0.111618,0.00413372,1.04103 beta-lactamase_39_R63Y,beta-lactamase_39_63,TEM-1,beta-lactamase_39,P62593,1.04104,NO,63,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-0.943,-4.16,3.217,,0.218,,B,1.2,-0.31,0.326,,44.06,ABH,-0.992333,0.0495842,0.00126938,1.04104 kka2_1:2_S54G,kka2_1:2_54,Kka2,kka2_1:2,P00552,1.04104,NO,54,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.471,-2.892,0.421,,0.408,S,b,0.27,1.01,0.393,,71.59,HPO,-2.259,0.295029,0.00782867,1.04104 Pab1_G193H,Pab1_193,Pab1,Pab1,P04147,1.04108,NO,193,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.414,-4.344,2.93,,,,,,,,,,POP,-1.55733,0.175299,0.0014922,1.04108 beta-lactamase_39_L55Q,beta-lactamase_39_55,TEM-1,beta-lactamase_39,P62593,1.04109,NO,55,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.86,-3.156,1.296,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.0495842,0.00403741,1.04109 beta-lactamase_625_V106R,beta-lactamase_625_106,TEM-1,beta-lactamase_625,P62593,1.04114,NO,106,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.218,-4.201,2.983,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.213352,0.00304168,1.04114 beta-lactamase_D33Q,beta-lactamase_33,TEM-1,beta-lactamase,P62593,1.04116,NO,33,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.321,-2.638,0.317,5.05203,0.366,H,A,0.23,0.33,2.032,,77.62,BAH,-2.12133,0.221079,0.00435556,1.04116 kka2_1:8_A25E,kka2_1:8_25,Kka2,kka2_1:8,P00552,1.04117,NO,25,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.496,-1.817,-0.679,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.100394,0.00595636,1.04117 kka2_1:8_A25E,kka2_1:8_25,Kka2,kka2_1:8,P00552,1.04117,NO,25,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.496,-1.817,-0.679,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.100394,0.00595636,1.04117 beta-lactamase_39_E87Q,beta-lactamase_39_87,TEM-1,beta-lactamase_39,P62593,1.04118,NO,87,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.421,-2.648,1.227,,0.048,,B,1.04,0.92,15.231,15.231,64.69,PAP,-1.969,0.0495842,0.00337888,1.04118 beta-lactamase_0_N274T,beta-lactamase_0_274,TEM-1,beta-lactamase_0,P62593,1.0412,NO,274,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.0500837,0.0110418,1.0412 beta-lactamase_625_F58V,beta-lactamase_625_58,TEM-1,beta-lactamase_625,P62593,1.04127,NO,58,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-2.914,-3.697,0.783,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.213352,0.00523369,1.04127 PSD95pdz3_D357C,PSD95pdz3_357,PSD95pdz3,PSD95pdz3,P31016,1.04127,NO,357,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.264,-4.769,3.505,5.22306,,,,,10.975,,,,OAP,-1.32367,0.0758425,0.000609015,1.04127 beta-lactamase_39_I244A,beta-lactamase_39_244,TEM-1,beta-lactamase_39,P62593,1.04129,NO,244,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.555,-3.008,1.453,,,E,B,0.48,-0.84,1.325,,77.62,OHH,-1.385,0.0495842,0.00605379,1.04129 beta-lactamase_T186M,beta-lactamase_186,TEM-1,beta-lactamase,P62593,1.04131,NO,186,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.522,-3.419,0.897,5.07364,0.396,H,A,0.3,-0.28,2.144,,77.62,HPP,-1.77633,0.221079,0.00485034,1.04131 beta-lactamase_2500_I45F,beta-lactamase_2500_45,TEM-1,beta-lactamase_2500,P62593,1.04133,NO,45,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-2.421,-3.147,0.726,,,E,B,0.48,-0.3,3.793,,77.62,HHA,-2.30267,0.361275,0.00452842,1.04133 PSD95pdz3_G333D,PSD95pdz3_333,PSD95pdz3,PSD95pdz3,P31016,1.04137,NO,333,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.008,-3.15,2.142,5.09445,,,,,48.755,,,,AOA,-1.22533,0.0758425,0.00092544,1.04137 beta-lactamase_0_G194S,beta-lactamase_0_194,TEM-1,beta-lactamase_0,P62593,1.04138,NO,194,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.396,-2.171,0.775,,0.276,S,b,0.29,0.36,3.017,,67.83,POA,-1.832,0.0500837,0.00392163,1.04138 beta-lactamase_0_M209A,beta-lactamase_0_209,TEM-1,beta-lactamase_0,P62593,1.04139,NO,209,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.442,-3.177,1.735,,,H,A,0.55,-0.97,3.876,,64.69,HHA,-1.52633,0.0500837,0.00625021,1.04139 beta-lactamase_0_P172G,beta-lactamase_0_172,TEM-1,beta-lactamase_0,P62593,1.04139,NO,172,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.998,-3.35,2.352,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.0500837,0.00312594,1.04139 beta-lactamase_39_N130S,beta-lactamase_39_130,TEM-1,beta-lactamase_39,P62593,1.04139,NO,130,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-0.798,-2.936,2.138,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.0495842,0.000683376,1.04139 kka2_1:8_R173S,kka2_1:8_173,Kka2,kka2_1:8,P00552,1.04139,NO,173,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.407,-3.482,1.075,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.100394,0.00784999,1.04139 kka2_1:8_R173S,kka2_1:8_173,Kka2,kka2_1:8,P00552,1.04139,NO,173,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.407,-3.482,1.075,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.100394,0.00784999,1.04139 beta-lactamase_0_T158N,beta-lactamase_0_158,TEM-1,beta-lactamase_0,P62593,1.04141,NO,158,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.116,-3.488,2.372,,0.036,,B,0.22,-0.85,1.041,,69.58,HPB,-1.269,0.0500837,0.00341825,1.04141 kka2_1:4_K175R,kka2_1:4_175,Kka2,kka2_1:4,P00552,1.04141,NO,175,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-2.897,-2.852,-0.045,,0.579,H,A,1.3,0.51,15.629,15.629,71.59,HBH,-1.82333,0.168804,0.00693093,1.04141 beta-lactamase_0_A247Y,beta-lactamase_0_247,TEM-1,beta-lactamase_0,P62593,1.04142,NO,247,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.0500837,0.00611275,1.04142 beta-lactamase_625_E26H,beta-lactamase_625_26,TEM-1,beta-lactamase_625,P62593,1.04143,NO,26,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.454,-4.609,2.155,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.213352,0.00297948,1.04143 beta-lactamase_39_E26M,beta-lactamase_39_26,TEM-1,beta-lactamase_39,P62593,1.04144,NO,26,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.454,-4.568,2.114,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.0495842,0.00297948,1.04144 beta-lactamase_39_P165H,beta-lactamase_39_165,TEM-1,beta-lactamase_39,P62593,1.04144,NO,165,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.373,-4.751,3.378,,0.203,T,A,0.52,-0.31,3.907,,73.78,AOA,-1.359,0.0495842,0.00549538,1.04144 kka2_1:4_L7M,kka2_1:4_7,Kka2,kka2_1:4,P00552,1.04144,NO,7,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.926,-2.658,0.732,,,,,,,3.012,,71.59,OHB,-2.12333,0.168804,0.00269456,1.04144 gb1_D272C,gb1_272,gb1,gb1,P06654,1.04147,NO,272,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.457,-5.004,3.547,,,,,,,0.234,,11.83,HAA,-1.54533,0.177985,0.00218257,1.04147 gb1_N234K,gb1_234,gb1,gb1,P06654,1.04147,NO,234,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-2.055,-1.684,-0.371,,,,,,,1.235,,45.54,HPO,-2.05067,0.177985,0.00242189,1.04147 beta-lactamase_39_F149S,beta-lactamase_39_149,TEM-1,beta-lactamase_39,P62593,1.0415,NO,149,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.299,-2.783,1.484,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.0495842,0.00418462,1.0415 beta-lactamase_625_K190A,beta-lactamase_625_190,TEM-1,beta-lactamase_625,P62593,1.04151,NO,190,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.994,-2.146,0.152,,0.371,H,A,2.34,0.16,29.753,29.753,77.62,BBH,-1.64167,0.213352,0.00574527,1.04151 beta-lactamase_L196Y,beta-lactamase_196,TEM-1,beta-lactamase,P62593,1.04153,NO,196,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-2.478,-4.286,1.808,,0.518,S,A,0.55,1.35,,,77.62,AHH,-1.839,0.221079,0.00512144,1.04153 PSD95pdz3_S371P,PSD95pdz3_371,PSD95pdz3,PSD95pdz3,P31016,1.04154,NO,371,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.86,-3.432,1.572,5.19744,,,,,17.1117,3.854,,87.71,HPB,-1.598,0.0758425,0.000847873,1.04154 E1_Ubiquitin_Q41L,E1_Ubiquitin_41,Uba1,E1_Ubiquitin,P0CG63,1.04156,NO,41,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-1.25,-3.175,1.925,,0.017,E,B,,-0.98,,,,PPB,-1.344,0.18783,0.00215097,1.04156 E1_Ubiquitin_Q41S,E1_Ubiquitin_41,Uba1,E1_Ubiquitin,P0CG63,1.04156,NO,41,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-1.25,-2.978,1.728,,0.017,E,B,,-0.98,,,,PPB,-1.344,0.18783,0.00215097,1.04156 E1_Ubiquitin_R74V,E1_Ubiquitin_74,Uba1,E1_Ubiquitin,P0CG63,1.04156,NO,74,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.302,-3.564,2.262,,0.838,T,A,,3.15,,,,HBO,-1.11333,0.18783,0.00180798,1.04156 beta-lactamase_0_D129S,beta-lactamase_0_129,TEM-1,beta-lactamase_0,P62593,1.04157,NO,129,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.816,-3.186,2.37,,,,B,0.75,-0.69,2.66,,34.97,PAP,-0.818,0.0500837,0.00109178,1.04157 beta-lactamase_39_F58V,beta-lactamase_39_58,TEM-1,beta-lactamase_39,P62593,1.04161,NO,58,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-2.914,-3.697,0.783,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.0495842,0.00523369,1.04161 kka2_1:2_S68G,kka2_1:2_68,Kka2,kka2_1:2,P00552,1.04163,NO,68,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.623,-2.541,-0.082,,0.48,H,A,0.27,-0.1,2.655,,71.59,HPH,-1.40767,0.295029,0.00608265,1.04163 PSD95pdz3_S350V,PSD95pdz3_350,PSD95pdz3,PSD95pdz3,P31016,1.04164,NO,350,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.519,-3.21,1.691,4.97629,,,,,25.01,,,,HPO,-1.29133,0.0758425,0.000704883,1.04164 beta-lactamase_39_S80W,beta-lactamase_39_80,TEM-1,beta-lactamase_39,P62593,1.04165,NO,80,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.029,-5.529,3.5,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.0495842,0.00565569,1.04165 beta-lactamase_39_T112E,beta-lactamase_39_112,TEM-1,beta-lactamase_39,P62593,1.04165,NO,112,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.186,-2.494,0.308,,0.921,T,A,0.22,1.06,2.87,,73.78,HPA,-1.925,0.0495842,0.00531334,1.04165 beta-lactamase_0_T264A,beta-lactamase_0_264,TEM-1,beta-lactamase_0,P62593,1.04167,NO,264,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.0500837,0.0119399,1.04167 kka2_1:4_T28C,kka2_1:4_28,Kka2,kka2_1:4,P00552,1.04169,NO,28,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.883,-5.036,3.153,,0.353,S,B,0.82,2.02,4.415,,63.64,PPH,-1.74467,0.168804,0.00743084,1.04169 beta-lactamase_39_R273F,beta-lactamase_39_273,TEM-1,beta-lactamase_39,P62593,1.0417,NO,273,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.314,-4.428,2.114,,0.564,H,A,1.2,1.57,2.163,,73.78,ABP,-1.841,0.0495842,0.0077952,1.0417 gb1_A274T,gb1_274,gb1,gb1,P06654,1.04172,NO,274,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.728,-3.197,1.469,,,,,,,4.162,4.162,11.83,AHP,-1.81767,0.177985,0.0068419,1.04172 gb1_V255I,gb1_255,gb1,gb1,P06654,1.04172,NO,255,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-3.127,-3.533,0.406,,,,,,,1.323,,45.54,BHH,-2.03867,0.177985,0.00408354,1.04172 beta-lactamase_625_K190G,beta-lactamase_625_190,TEM-1,beta-lactamase_625,P62593,1.04174,NO,190,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.994,-3.44,1.446,,0.371,H,A,2.34,0.16,29.753,29.753,77.62,BBH,-1.64167,0.213352,0.00574527,1.04174 beta-lactamase_625_V106T,beta-lactamase_625_106,TEM-1,beta-lactamase_625,P62593,1.04184,NO,106,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.218,-3.428,2.21,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.213352,0.00304168,1.04184 beta-lactamase_156_H110S,beta-lactamase_156_110,TEM-1,beta-lactamase_156,P62593,1.04186,NO,110,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-1.706,-3.537,1.831,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.111618,0.00441499,1.04186 beta-lactamase_0_R242G,beta-lactamase_0_242,TEM-1,beta-lactamase_0,P62593,1.04187,NO,242,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.319,-3.802,2.483,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.0500837,0.00452879,1.04187 beta-lactamase_625_E272V,beta-lactamase_625_272,TEM-1,beta-lactamase_625,P62593,1.04187,NO,272,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.213352,0.00545371,1.04187 beta-lactamase_R202K,beta-lactamase_202,TEM-1,beta-lactamase,P62593,1.0419,NO,202,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.292,-3.005,1.713,5.16273,0.188,H,A,0.68,0.62,1.918,,77.62,PBP,-1.54767,0.221079,0.00321899,1.0419 PSD95pdz3_Y392H,PSD95pdz3_392,PSD95pdz3,PSD95pdz3,P31016,1.04194,NO,392,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-1.437,-3.462,2.025,5.20337,,,,,11.725,,,,PHB,-1.51733,0.0758425,0.000935211,1.04194 beta-lactamase_S201S,beta-lactamase_201,TEM-1,beta-lactamase,P62593,1.04197,NO,201,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.183,-1.183,,4.85496,0.064,H,A,0.77,-0.07,4.045,,64.69,HPB,-1.451,0.221079,0.00198815,1.04197 kka2_1:8_I246V,kka2_1:8_246,Kka2,kka2_1:8,P00552,1.04197,NO,246,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-2.008,-2.046,0.038,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.100394,0.0139479,1.04197 kka2_1:8_I246V,kka2_1:8_246,Kka2,kka2_1:8,P00552,1.04197,NO,246,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-2.008,-2.046,0.038,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.100394,0.0139479,1.04197 beta-lactamase_39_I285R,beta-lactamase_39_285,TEM-1,beta-lactamase_39,P62593,1.04201,NO,285,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.0495842,0.101555,1.04201 beta-lactamase_39_A211D,beta-lactamase_39_211,TEM-1,beta-lactamase_39,P62593,1.04203,NO,211,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.896,-1.934,0.038,,0.369,T,A,0.46,-0.69,1.419,,77.62,AHA,-1.94633,0.0495842,0.00648183,1.04203 PSD95pdz3_D332F,PSD95pdz3_332,PSD95pdz3,PSD95pdz3,P31016,1.04203,NO,332,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.264,-3.974,2.71,6.09878,,,,,48.762,,,,AAO,-1.22533,0.0758425,0.000937818,1.04203 kka2_1:8_A229L,kka2_1:8_229,Kka2,kka2_1:8,P00552,1.04204,NO,229,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.739,-3.501,1.762,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.100394,0.00942138,1.04204 kka2_1:8_A229L,kka2_1:8_229,Kka2,kka2_1:8,P00552,1.04204,NO,229,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.739,-3.501,1.762,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.100394,0.00942138,1.04204 kka2_1:2_E160V,kka2_1:2_160,Kka2,kka2_1:2,P00552,1.04205,NO,160,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.683,-3.733,2.05,,0.989,G,A,1.04,2.28,3.948,,71.59,AAA,-1.36133,0.295029,0.00935762,1.04205 beta-lactamase_2500_K190T,beta-lactamase_2500_190,TEM-1,beta-lactamase_2500,P62593,1.04207,NO,190,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.994,-2.389,0.395,,0.371,H,A,2.34,0.16,29.753,29.753,77.62,BBH,-1.64167,0.361275,0.00574527,1.04207 kka2_1:8_L93F,kka2_1:8_93,Kka2,kka2_1:8,P00552,1.04207,NO,93,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.815,-3.719,2.904,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.100394,0.00131498,1.04207 kka2_1:8_L93F,kka2_1:8_93,Kka2,kka2_1:8,P00552,1.04207,NO,93,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.815,-3.719,2.904,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.100394,0.00131498,1.04207 beta-lactamase_39_V106N,beta-lactamase_39_106,TEM-1,beta-lactamase_39,P62593,1.04208,NO,106,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.218,-4.217,2.999,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.0495842,0.00304168,1.04208 beta-lactamase_39_T186V,beta-lactamase_39_186,TEM-1,beta-lactamase_39,P62593,1.04209,NO,186,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.522,-3.557,1.035,,0.396,H,A,0.22,-0.28,0.515,,77.62,HPP,-1.77633,0.0495842,0.00485034,1.04209 gb1_T275S,gb1_275,gb1,gb1,P06654,1.04209,NO,275,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.727,-1.962,0.235,,,,,,,0.511,,35.71,HPB,-1.637,0.177985,0.00606618,1.04209 gb1_T275W,gb1_275,gb1,gb1,P06654,1.04209,NO,275,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.727,-5.154,3.427,,,,,,,0.511,,35.71,HPB,-1.637,0.177985,0.00606618,1.04209 PSD95pdz3_V365G,PSD95pdz3_365,PSD95pdz3,PSD95pdz3,P31016,1.04211,NO,365,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.592,-3.034,1.442,5.03791,,,,,18.9657,2.364,,81.35,OHA,-1.288,0.0758425,0.000649764,1.04211 PSD95pdz3_I377H,PSD95pdz3_377,PSD95pdz3,PSD95pdz3,P31016,1.04212,NO,377,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.873,-4.739,2.866,4.9532,,,,,19.185,2.364,,87.71,HHH,-1.49567,0.0758425,0.000795475,1.04212 beta-lactamase_0_Q37S,beta-lactamase_0_37,TEM-1,beta-lactamase_0,P62593,1.04215,NO,37,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.134,-2.839,0.705,,0.613,H,A,0.64,1.98,4.001,,73.08,APH,-2.06967,0.0500837,0.00425833,1.04215 kka2_1:4_L152M,kka2_1:4_152,Kka2,kka2_1:4,P00552,1.04218,NO,152,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.521,-3.313,1.792,,0.547,,A,1.59,1.36,2.318,,63.64,OHH,-1.162,0.168804,0.00674868,1.04218 beta-lactamase_39_S201A,beta-lactamase_39_201,TEM-1,beta-lactamase_39,P62593,1.04219,NO,201,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.183,-2.127,0.944,,0.064,H,A,0.27,-0.07,3.54,,64.69,HPB,-1.451,0.0495842,0.00198815,1.04219 beta-lactamase_39_G141K,beta-lactamase_39_141,TEM-1,beta-lactamase_39,P62593,1.04221,NO,141,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.828,-3.62,2.792,,0.575,T,l,0.29,-0.28,0.722,,64.69,HOO,-1.08933,0.0495842,0.0012419,1.04221 kka2_1:2_E231N,kka2_1:2_231,Kka2,kka2_1:2,P00552,1.04222,NO,231,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.002,-1.271,-0.731,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.295029,0.00732383,1.04222 beta-lactamase_0_G142E,beta-lactamase_0_142,TEM-1,beta-lactamase_0,P62593,1.04223,NO,142,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.707,-3.628,2.921,,0.034,,p,0.29,-0.64,1.947,,64.69,OOO,-0.834,0.0500837,0.00060149,1.04223 beta-lactamase_39_A235C,beta-lactamase_39_235,TEM-1,beta-lactamase_39,P62593,1.04223,NO,235,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.266,-4.693,3.427,,0.32,E,B,0.46,-0.86,1.344,,50,OHO,-0.89,0.0495842,0.00493474,1.04223 beta-lactamase_156_R176C,beta-lactamase_156_176,TEM-1,beta-lactamase_156,P62593,1.04224,NO,176,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-0.863,-5.087,4.224,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.111618,0.00105554,1.04224 PSD95pdz3_G344Q,PSD95pdz3_344,PSD95pdz3,PSD95pdz3,P31016,1.04227,NO,344,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.008,-3.806,2.798,4.83855,,,,,14.06,,,,HOO,-1.10767,0.0758425,0.00078498,1.04227 beta-lactamase_0_T138G,beta-lactamase_0_138,TEM-1,beta-lactamase_0,P62593,1.04235,NO,138,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.506,-2.767,0.261,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.0500837,0.00487868,1.04235 beta-lactamase_2500_P25E,beta-lactamase_2500_25,TEM-1,beta-lactamase_2500,P62593,1.0424,NO,25,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.526,-2.543,1.017,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.361275,0.00347571,1.0424 kka2_1:8_W15G,kka2_1:8_15,Kka2,kka2_1:8,P00552,1.0424,NO,15,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-1.392,-3.656,2.264,,0.01,G,A,1.51,0.15,0.827,,52.27,HHH,-2.10533,0.100394,0.00585505,1.0424 kka2_1:8_W15G,kka2_1:8_15,Kka2,kka2_1:8,P00552,1.0424,NO,15,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,-1.392,-3.656,2.264,,0.01,G,A,1.51,0.15,0.827,,52.27,HHH,-2.10533,0.100394,0.00585505,1.0424 kka2_1:4_D82E,kka2_1:4_82,Kka2,kka2_1:4,P00552,1.04245,NO,82,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.946,-2.436,0.49,,0.341,E,b,0.75,0.52,11.923,11.923,63.64,HAH,-1.98,0.168804,0.00637516,1.04245 kka2_1:2_L152R,kka2_1:2_152,Kka2,kka2_1:2,P00552,1.04247,NO,152,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.521,-2.523,1.002,,0.547,.,A,0.55,1.36,4.526,,63.64,OHH,-1.162,0.295029,0.00674868,1.04247 beta-lactamase_0_A247F,beta-lactamase_0_247,TEM-1,beta-lactamase_0,P62593,1.04249,NO,247,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.0500837,0.00611275,1.04249 PSD95pdz3_Q374E,PSD95pdz3_374,PSD95pdz3,PSD95pdz3,P31016,1.04249,NO,374,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-1.699,-2.447,0.748,5.38825,,,,,17.3289,,,,APH,-1.47,0.0758425,0.000372298,1.04249 beta-lactamase_39_G141C,beta-lactamase_39_141,TEM-1,beta-lactamase_39,P62593,1.04252,NO,141,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.828,-5.167,4.339,,0.575,T,l,0.29,-0.28,0.722,,64.69,HOO,-1.08933,0.0495842,0.0012419,1.04252 beta-lactamase_39_I285E,beta-lactamase_39_285,TEM-1,beta-lactamase_39,P62593,1.04253,NO,285,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.0495842,0.101555,1.04253 kka2_1:4_E142D,kka2_1:4_142,Kka2,kka2_1:4,P00552,1.04253,NO,142,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.221,-3.049,0.828,,0.471,H,A,1.52,0.85,3.693,,65.53,HAB,-2.08033,0.168804,0.00748883,1.04253 kka2_1:4_I254T,kka2_1:4_254,Kka2,kka2_1:4,P00552,1.04253,NO,254,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.933,-3.596,1.663,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.168804,0.0132375,1.04253 beta-lactamase_0_Q86D,beta-lactamase_0_86,TEM-1,beta-lactamase_0,P62593,1.04254,NO,86,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.4,-2.27,-0.13,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.0500837,0.00450027,1.04254 kka2_1:2_G234C,kka2_1:2_234,Kka2,kka2_1:2,P00552,1.04254,NO,234,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-2.9,-5.225,2.325,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.295029,0.00984449,1.04254 beta-lactamase_39_R118W,beta-lactamase_39_118,TEM-1,beta-lactamase_39,P62593,1.04257,NO,118,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.413,-5.439,3.026,,0.457,H,A,1.2,1.39,3.961,,77.62,HBA,-1.785,0.0495842,0.00538794,1.04257 beta-lactamase_0_T139E,beta-lactamase_0_139,TEM-1,beta-lactamase_0,P62593,1.04258,NO,139,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.901,-2.44,0.539,,0.216,H,A,0.22,0.39,0.421,,77.62,PPH,-2.04667,0.0500837,0.00441837,1.04258 beta-lactamase_39_A148W,beta-lactamase_39_148,TEM-1,beta-lactamase_39,P62593,1.04258,NO,148,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.757,-5.497,3.74,,0.379,H,A,0.46,-0.55,3.551,,72.73,PHH,-1.40167,0.0495842,0.00547053,1.04258 gb1_A274M,gb1_274,gb1,gb1,P06654,1.04259,NO,274,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.728,-4.527,2.799,,,,,,,4.162,4.162,11.83,AHP,-1.81767,0.177985,0.0068419,1.04259 beta-lactamase_39_R91Q,beta-lactamase_39_91,TEM-1,beta-lactamase_39,P62593,1.0426,NO,91,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.392,-2.363,0.971,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.0495842,0.00380226,1.0426 beta-lactamase_L19N,beta-lactamase_19,TEM-1,beta-lactamase,P62593,1.0426,NO,19,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.682,-3.963,2.281,,,,,,,4.261,,93.01,OHO,-1.894,0.221079,0.00215974,1.0426 beta-lactamase_N173M,beta-lactamase_173,TEM-1,beta-lactamase,P62593,1.0426,NO,173,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-2.663,-4.901,2.238,7.02497,1.044,T,l,0.09,1.25,1.88,,77.62,OPA,-1.46633,0.221079,0.0033769,1.0426 beta-lactamase_N98F,beta-lactamase_98,TEM-1,beta-lactamase,P62593,1.0426,NO,98,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-2.973,-3.271,0.298,6.59973,0.963,G,A,1.07,1.35,1.332,,77.62,PPA,-2.07867,0.221079,0.00505389,1.0426 beta-lactamase_R273K,beta-lactamase_273,TEM-1,beta-lactamase,P62593,1.0426,NO,273,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.314,-2.204,-0.11,,0.564,H,A,1.2,1.57,,,73.78,ABP,-1.841,0.221079,0.0077952,1.0426 beta-lactamase_0_S57D,beta-lactamase_0_57,TEM-1,beta-lactamase_0,P62593,1.04262,NO,57,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.918,-3.634,1.716,,0.352,E,B,0.27,-0.18,1.454,,72.73,APH,-2.29167,0.0500837,0.00492804,1.04262 beta-lactamase_156_E87A,beta-lactamase_156_87,TEM-1,beta-lactamase_156,P62593,1.04262,NO,87,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.421,-3.209,1.788,,0.048,,B,1.04,0.92,1.754,,64.69,PAP,-1.969,0.111618,0.00337888,1.04262 beta-lactamase_0_T179V,beta-lactamase_0_179,TEM-1,beta-lactamase_0,P62593,1.04265,NO,179,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.085,-3.247,2.162,,,E,B,0.22,-1.38,0.367,,73.08,PPH,-1.557,0.0500837,0.00226045,1.04265 beta-lactamase_0_N98W,beta-lactamase_0_98,TEM-1,beta-lactamase_0,P62593,1.04269,NO,98,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-2.973,-5.455,2.482,,0.963,G,A,0.61,1.35,14.853,14.853,77.62,PPA,-2.07867,0.0500837,0.00505389,1.04269 gb1_A250L,gb1_250,gb1,gb1,P06654,1.04271,NO,250,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.713,-3.205,1.492,,,,,,,3.465,,45.54,HHP,-1.74867,0.177985,0.00332003,1.04271 beta-lactamase_0_E210W,beta-lactamase_0_210,TEM-1,beta-lactamase_0,P62593,1.04273,NO,210,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.319,-5.437,3.118,,0.476,H,A,1.04,0.75,3.618,,77.62,HAH,-1.88567,0.0500837,0.00663582,1.04273 PSD95pdz3_K355F,PSD95pdz3_355,PSD95pdz3,PSD95pdz3,P31016,1.04273,NO,355,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.416,-3.974,2.558,5.56865,,,,,17.2556,,,,BBO,-1.33533,0.0758425,0.00063703,1.04273 kka2_1:8_D154H,kka2_1:8_154,Kka2,kka2_1:8,P00552,1.04275,NO,154,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.876,-4.446,3.57,,0.457,,b,0.29,1.48,0.844,,52.65,HAP,-1.52467,0.100394,0.00292633,1.04275 kka2_1:8_D154H,kka2_1:8_154,Kka2,kka2_1:8,P00552,1.04275,NO,154,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.876,-4.446,3.57,,0.457,,b,0.29,1.48,0.844,,52.65,HAP,-1.52467,0.100394,0.00292633,1.04275 kka2_1:8_P76Y,kka2_1:8_76,Kka2,kka2_1:8,P00552,1.04275,NO,76,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.449,-4.443,2.994,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.100394,0.00625685,1.04275 kka2_1:8_P76Y,kka2_1:8_76,Kka2,kka2_1:8,P00552,1.04275,NO,76,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.449,-4.443,2.994,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.100394,0.00625685,1.04275 kka2_1:8_V214L,kka2_1:8_214,Kka2,kka2_1:8,P00552,1.04275,NO,214,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.261,-2.012,0.751,,0.117,E,B,1.48,-0.31,1.859,,64.39,OHH,-0.941667,0.100394,0.00692782,1.04275 kka2_1:8_V214L,kka2_1:8_214,Kka2,kka2_1:8,P00552,1.04275,NO,214,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.261,-2.012,0.751,,0.117,E,B,1.48,-0.31,1.859,,64.39,OHH,-0.941667,0.100394,0.00692782,1.04275 beta-lactamase_39_A211G,beta-lactamase_39_211,TEM-1,beta-lactamase_39,P62593,1.04276,NO,211,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.896,-2.355,0.459,,0.369,T,A,0.46,-0.69,1.419,,77.62,AHA,-1.94633,0.0495842,0.00648183,1.04276 beta-lactamase_39_L197R,beta-lactamase_39_197,TEM-1,beta-lactamase_39,P62593,1.04277,NO,197,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-0.853,-3.93,3.077,,0.007,S,B,0.55,0.33,1.559,,60.14,HHP,-1.833,0.0495842,0.00144602,1.04277 beta-lactamase_0_A225F,beta-lactamase_0_225,TEM-1,beta-lactamase_0,P62593,1.04278,NO,225,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.845,-4.402,2.557,,1,T,B,0.46,-0.38,11.722,11.722,74.48,OHO,-1.39967,0.0500837,0.00465057,1.04278 beta-lactamase_39_A211L,beta-lactamase_39_211,TEM-1,beta-lactamase_39,P62593,1.04284,NO,211,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.896,-3.595,1.699,,0.369,T,A,0.46,-0.69,1.419,,77.62,AHA,-1.94633,0.0495842,0.00648183,1.04284 beta-lactamase_0_L167N,beta-lactamase_0_167,TEM-1,beta-lactamase_0,P62593,1.04286,NO,167,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.138,-4.008,2.87,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.0500837,0.00303566,1.04286 beta-lactamase_0_E166T,beta-lactamase_0_166,TEM-1,beta-lactamase_0,P62593,1.04288,NO,166,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.756,-2.857,1.101,,0.508,G,A,1.04,1.05,17.227,17.227,73.08,OAH,-1.42233,0.0500837,0.00512989,1.04288 PSD95pdz3_D366A,PSD95pdz3_366,PSD95pdz3,PSD95pdz3,P31016,1.04288,NO,366,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.264,-2.984,1.72,5.55684,,,,,20.2375,,,,HAH,-1.401,0.0758425,0.000481272,1.04288 PSD95pdz3_I316V,PSD95pdz3_316,PSD95pdz3,PSD95pdz3,P31016,1.0429,NO,316,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.63,-2.085,0.455,5.46166,,,,,19.005,,,,HHB,-1.62733,0.0758425,0.00112762,1.0429 PSD95pdz3_G335Q,PSD95pdz3_335,PSD95pdz3,PSD95pdz3,P31016,1.04292,NO,335,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.008,-3.806,2.798,4.76223,,,,,22.4225,,,,AOH,-1.34733,0.0758425,0.000900493,1.04292 beta-lactamase_0_E102N,beta-lactamase_0_102,TEM-1,beta-lactamase_0,P62593,1.04295,NO,102,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.118,-3.596,1.478,,0.722,S,B,1.04,1.82,4.773,,73.08,HAH,-1.581,0.0500837,0.00486633,1.04295 gb1_N234H,gb1_234,gb1,gb1,P06654,1.04296,NO,234,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-2.055,-4.084,2.029,,,,,,,1.235,,45.54,HPO,-2.05067,0.177985,0.00242189,1.04296 PSD95pdz3_I314E,PSD95pdz3_314,PSD95pdz3,PSD95pdz3,P31016,1.04296,NO,314,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.628,-3.571,1.943,5.39919,,,,,15.7775,0.397,,81.35,BHH,-1.61167,0.0758425,0.0012606,1.04296 PSD95pdz3_E334G,PSD95pdz3_334,PSD95pdz3,PSD95pdz3,P31016,1.04297,NO,334,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.404,-3.04,1.636,5.60175,,,,,53.09,,,,OAO,-1.14,0.0758425,0.000912998,1.04297 beta-lactamase_2500_E210F,beta-lactamase_2500_210,TEM-1,beta-lactamase_2500,P62593,1.04298,NO,210,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.319,-4.128,1.809,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.361275,0.00663582,1.04298 beta-lactamase_39_E46D,beta-lactamase_39_46,TEM-1,beta-lactamase_39,P62593,1.04298,NO,46,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.94,-3.652,1.712,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.0495842,0.00427568,1.04298 kka2_1:8_D156Q,kka2_1:8_156,Kka2,kka2_1:8,P00552,1.04299,NO,156,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.696,-3.891,2.195,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.100394,0.00926998,1.04299 kka2_1:8_D156Q,kka2_1:8_156,Kka2,kka2_1:8,P00552,1.04299,NO,156,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.696,-3.891,2.195,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.100394,0.00926998,1.04299 beta-lactamase_625_E26M,beta-lactamase_625_26,TEM-1,beta-lactamase_625,P62593,1.043,NO,26,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.454,-4.568,2.114,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.213352,0.00297948,1.043 kka2_1:4_A79L,kka2_1:4_79,Kka2,kka2_1:4,P00552,1.04301,NO,79,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.368,-3.577,1.209,,0.563,.,B,0.46,-0.43,2.291,,71.59,HHH,-1.752,0.168804,0.00664821,1.04301 beta-lactamase_0_E61R,beta-lactamase_0_61,TEM-1,beta-lactamase_0,P62593,1.04303,NO,61,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.115,-3.845,1.73,,0.775,T,a,1.04,1.29,34.763,34.763,77.62,OAA,-1.92567,0.0500837,0.00440955,1.04303 beta-lactamase_0_G216S,beta-lactamase_0_216,TEM-1,beta-lactamase_0,P62593,1.04304,NO,216,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.477,-3.283,1.806,,0.437,I,A,0.29,-0.58,0.834,,74.48,HOO,-1.68067,0.0500837,0.00639568,1.04304 gb1_D262K,gb1_262,gb1,gb1,P06654,1.04308,NO,262,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-3.132,-2.166,-0.966,,,,,,,1.304,,45.54,PAP,-2.05233,0.177985,0.00413102,1.04308 beta-lactamase_0_A132W,beta-lactamase_0_132,TEM-1,beta-lactamase_0,P62593,1.04309,NO,132,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.9,-5.372,4.472,,,H,A,0.46,-0.93,2.249,,64.69,PHH,-1.138,0.0500837,0.000962524,1.04309 beta-lactamase_0_P255A,beta-lactamase_0_255,TEM-1,beta-lactamase_0,P62593,1.04309,NO,255,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.0500837,0.00499612,1.04309 kka2_1:8_I196M,kka2_1:8_196,Kka2,kka2_1:8,P00552,1.04309,NO,196,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-2.115,-3.213,1.098,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.100394,0.0107273,1.04309 kka2_1:8_I196M,kka2_1:8_196,Kka2,kka2_1:8,P00552,1.04309,NO,196,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-2.115,-3.213,1.098,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.100394,0.0107273,1.04309 PSD95pdz3_L349N,PSD95pdz3_349,PSD95pdz3,PSD95pdz3,P31016,1.04309,NO,349,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.347,-3.805,2.458,5.14696,,,,,24.6438,,,,AHP,-1.37667,0.0758425,0.00071841,1.04309 PSD95pdz3_R368K,PSD95pdz3_368,PSD95pdz3,PSD95pdz3,P31016,1.04309,NO,368,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.582,-2.464,0.882,6.13355,,,,,18.1818,,,,HBP,-1.50033,0.0758425,0.000451517,1.04309 beta-lactamase_39_I93T,beta-lactamase_39_93,TEM-1,beta-lactamase_39,P62593,1.0431,NO,93,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.401,-2.729,1.328,,0.128,E,B,0.48,0.44,1.757,,67.83,BHB,-1.873,0.0495842,0.00527066,1.0431 beta-lactamase_625_E272K,beta-lactamase_625_272,TEM-1,beta-lactamase_625,P62593,1.04314,NO,272,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.213352,0.00545371,1.04314 beta-lactamase_0_A124K,beta-lactamase_0_124,TEM-1,beta-lactamase_0,P62593,1.04318,NO,124,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.181,-3.561,2.38,,,H,A,0.46,-0.9,1.876,,64.34,HHH,-1.152,0.0500837,0.00481399,1.04318 kka2_1:8_E96M,kka2_1:8_96,Kka2,kka2_1:8,P00552,1.04319,NO,96,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.573,-4.64,2.067,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.100394,0.00369441,1.04319 kka2_1:8_E96M,kka2_1:8_96,Kka2,kka2_1:8,P00552,1.04319,NO,96,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.573,-4.64,2.067,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.100394,0.00369441,1.04319 beta-lactamase_39_R220D,beta-lactamase_39_220,TEM-1,beta-lactamase_39,P62593,1.04321,NO,220,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-0.942,-3.72,2.778,,0.295,I,A,1.2,-0.76,1.596,,74.48,HBP,-1.33633,0.0495842,0.00232421,1.04321 kka2_1:8_A87S,kka2_1:8_87,Kka2,kka2_1:8,P00552,1.04322,NO,87,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.917,-2.911,0.994,,1.039,S,L,0.46,1.57,16.115,16.115,65.53,AHO,-1.822,0.100394,0.00791281,1.04322 kka2_1:8_A87S,kka2_1:8_87,Kka2,kka2_1:8,P00552,1.04322,NO,87,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.917,-2.911,0.994,,1.039,S,L,0.46,1.57,16.115,16.115,65.53,AHO,-1.822,0.100394,0.00791281,1.04322 kka2_1:1_G43T,kka2_1:1_43,Kka2,kka2_1:1,P00552,1.04324,NO,43,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.587,-2.998,1.411,,0.862,T,l,0.75,-0.67,2.247,,63.26,POB,-2.18533,0.520039,0.0071925,1.04324 beta-lactamase_625_F58N,beta-lactamase_625_58,TEM-1,beta-lactamase_625,P62593,1.04325,NO,58,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-2.914,-3.795,0.881,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.213352,0.00523369,1.04325 kka2_1:2_K138V,kka2_1:2_138,Kka2,kka2_1:2,P00552,1.04328,NO,138,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-2.5,-3.083,0.583,,0.594,H,A,2.34,0.98,21.038,21.038,71.59,HBB,-2.48833,0.295029,0.00628542,1.04328 beta-lactamase_39_H110A,beta-lactamase_39_110,TEM-1,beta-lactamase_39,P62593,1.0433,NO,110,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-1.706,-3.353,1.647,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.0495842,0.00441499,1.0433 E1_Ubiquitin_L71K,E1_Ubiquitin_71,Uba1,E1_Ubiquitin,P0CG63,1.04332,NO,71,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.039,-3.499,2.46,,0.591,E,B,,-0.69,,,,BHB,-1.19433,0.18783,0.00148349,1.04332 E1_Ubiquitin_L73M,E1_Ubiquitin_73,Uba1,E1_Ubiquitin,P0CG63,1.04332,NO,73,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.039,-3.622,2.583,,0.518,,B,1.3,1,,,,BHB,-1.175,0.18783,0.00111236,1.04332 E1_Ubiquitin_Q41G,E1_Ubiquitin_41,Uba1,E1_Ubiquitin,P0CG63,1.04332,NO,41,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-1.25,-3.175,1.925,,0.017,E,B,,-0.98,,,,PPB,-1.344,0.18783,0.00215097,1.04332 gb1_T275R,gb1_275,gb1,gb1,P06654,1.04333,NO,275,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.727,-3.712,1.985,,,,,,,0.511,,35.71,HPB,-1.637,0.177985,0.00606618,1.04333 beta-lactamase_625_V106D,beta-lactamase_625_106,TEM-1,beta-lactamase_625,P62593,1.04335,NO,106,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.218,-4.056,2.838,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.213352,0.00304168,1.04335 kka2_1:2_D154N,kka2_1:2_154,Kka2,kka2_1:2,P00552,1.04335,NO,154,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.876,-2.341,1.465,,0.457,,b,0.29,1.48,3.631,,52.65,HAP,-1.52467,0.295029,0.00292633,1.04335 PSD95pdz3_A343D,PSD95pdz3_343,PSD95pdz3,PSD95pdz3,P31016,1.04336,NO,343,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.307,-3.375,2.068,5.585,,,,,14.728,,,,HHO,-1.22067,0.0758425,0.000798084,1.04336 beta-lactamase_L19T,beta-lactamase_19,TEM-1,beta-lactamase,P62593,1.04338,NO,19,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.682,-2.578,0.896,,,,,,,4.261,,93.01,OHO,-1.894,0.221079,0.00215974,1.04338 PSD95pdz3_L360Y,PSD95pdz3_360,PSD95pdz3,PSD95pdz3,P31016,1.0434,NO,360,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.431,-3.714,2.283,5.09284,,,,,14.2425,1.419,,86.88,HHP,-1.52667,0.0758425,0.000770471,1.0434 PSD95pdz3_Y392F,PSD95pdz3_392,PSD95pdz3,PSD95pdz3,P31016,1.04341,NO,392,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-1.437,-2.624,1.187,5.20337,,,,,11.725,,,,PHB,-1.51733,0.0758425,0.000935211,1.04341 gb1_A274W,gb1_274,gb1,gb1,P06654,1.04345,NO,274,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.728,-5.24,3.512,,,,,,,4.162,4.162,11.83,AHP,-1.81767,0.177985,0.0068419,1.04345 beta-lactamase_39_E26W,beta-lactamase_39_26,TEM-1,beta-lactamase_39,P62593,1.0435,NO,26,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.454,-5.402,2.948,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.0495842,0.00297948,1.0435 beta-lactamase_39_V106W,beta-lactamase_39_106,TEM-1,beta-lactamase_39,P62593,1.04351,NO,106,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.218,-5.22,4.002,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.0495842,0.00304168,1.04351 beta-lactamase_39_P217D,beta-lactamase_39_217,TEM-1,beta-lactamase_39,P62593,1.04354,NO,217,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-2.062,-2.498,0.436,,0.496,I,A,0.52,-0.33,21.172,21.172,74.48,OOH,-1.64333,0.0495842,0.00463211,1.04354 kka2_1:8_V80K,kka2_1:8_80,Kka2,kka2_1:8,P00552,1.04355,NO,80,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.144,-3.802,2.658,,0.358,E,B,1.48,-0.24,2.562,,63.64,HHH,-1.64633,0.100394,0.00488211,1.04355 kka2_1:8_V80K,kka2_1:8_80,Kka2,kka2_1:8,P00552,1.04355,NO,80,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.144,-3.802,2.658,,0.358,E,B,1.48,-0.24,2.562,,63.64,HHH,-1.64633,0.100394,0.00488211,1.04355 beta-lactamase_A16G,beta-lactamase_16,TEM-1,beta-lactamase,P62593,1.04357,NO,16,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,,-1.9,-0.035,,,,,,,,,,HHH,,0.221079,0.00245392,1.04357 beta-lactamase_N152Q,beta-lactamase_152,TEM-1,beta-lactamase,P62593,1.04357,NO,152,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-2.757,-2.534,-0.223,5.98571,0.863,H,A,0.09,0.92,2.061,,77.62,BPH,-2.97,0.221079,0.00471429,1.04357 gb1_A274Y,gb1_274,gb1,gb1,P06654,1.04357,NO,274,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.728,-4.08,2.352,,,,,,,4.162,4.162,11.83,AHP,-1.81767,0.177985,0.0068419,1.04357 kka2_1:8_A255T,kka2_1:8_255,Kka2,kka2_1:8,P00552,1.04357,NO,255,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.715,-3.017,1.302,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.100394,0.0126809,1.04357 kka2_1:8_A255T,kka2_1:8_255,Kka2,kka2_1:8,P00552,1.04357,NO,255,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.715,-3.017,1.302,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.100394,0.0126809,1.04357 beta-lactamase_39_V106E,beta-lactamase_39_106,TEM-1,beta-lactamase_39,P62593,1.04359,NO,106,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.218,-3.859,2.641,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.0495842,0.00304168,1.04359 beta-lactamase_39_E108D,beta-lactamase_39_108,TEM-1,beta-lactamase_39,P62593,1.0436,NO,108,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.46,-2.67,1.21,,0.572,G,A,1.04,1.87,20.151,20.151,72.73,PAB,-1.437,0.0495842,0.00413372,1.0436 kka2_1:8_A41W,kka2_1:8_41,Kka2,kka2_1:8,P00552,1.0436,NO,41,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.879,-3.701,1.822,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.100394,0.00543332,1.0436 kka2_1:8_A41W,kka2_1:8_41,Kka2,kka2_1:8,P00552,1.0436,NO,41,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.879,-3.701,1.822,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.100394,0.00543332,1.0436 Pab1_T159M,Pab1_159,Pab1,Pab1,P04147,1.04366,NO,159,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.445,-4.311,2.866,,,,,,,2.531,,79.03,HPA,-1.19467,0.175299,0.00133849,1.04366 beta-lactamase_39_S80Q,beta-lactamase_39_80,TEM-1,beta-lactamase_39,P62593,1.04368,NO,80,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.029,-3.941,1.912,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.0495842,0.00565569,1.04368 gb1_E268H,gb1_268,gb1,gb1,P06654,1.0437,NO,268,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.918,-4.282,2.364,,,,,,,0.637,,37.28,OAH,-1.59733,0.177985,0.00423953,1.0437 beta-lactamase_39_T138N,beta-lactamase_39_138,TEM-1,beta-lactamase_39,P62593,1.04376,NO,138,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.506,-2.961,0.455,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.0495842,0.00487868,1.04376 PSD95pdz3_T387S,PSD95pdz3_387,PSD95pdz3,PSD95pdz3,P31016,1.04377,NO,387,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.391,-2.617,1.226,5.20757,,,,,18.8043,,,,HPH,-1.49533,0.0758425,0.000167911,1.04377 beta-lactamase_0_R273S,beta-lactamase_0_273,TEM-1,beta-lactamase_0,P62593,1.04378,NO,273,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.314,-3.326,1.012,,0.564,H,A,1.2,1.57,20.248,20.248,73.78,ABP,-1.841,0.0500837,0.0077952,1.04378 beta-lactamase_625_I45F,beta-lactamase_625_45,TEM-1,beta-lactamase_625,P62593,1.0438,NO,45,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-2.421,-3.147,0.726,,,E,B,0.48,-0.3,3.642,,77.62,HHA,-2.30267,0.213352,0.00452842,1.0438 beta-lactamase_0_G243F,beta-lactamase_0_243,TEM-1,beta-lactamase_0,P62593,1.04381,NO,243,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.0500837,0.00464034,1.04381 beta-lactamase_0_T269V,beta-lactamase_0_269,TEM-1,beta-lactamase_0,P62593,1.04381,NO,269,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.0500837,0.00950944,1.04381 kka2_1:8_T125C,kka2_1:8_125,Kka2,kka2_1:8,P00552,1.04381,NO,125,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.622,-5.084,2.462,,0.791,T,A,0.22,0.33,2.675,,92.05,BPH,-1.56933,0.100394,0.00821755,1.04381 kka2_1:8_T125C,kka2_1:8_125,Kka2,kka2_1:8,P00552,1.04381,NO,125,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.622,-5.084,2.462,,0.791,T,A,0.22,0.33,2.675,,92.05,BPH,-1.56933,0.100394,0.00821755,1.04381 beta-lactamase_625_K190R,beta-lactamase_625_190,TEM-1,beta-lactamase_625,P62593,1.04382,NO,190,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.994,-2.302,0.308,,0.371,H,A,2.34,0.16,29.753,29.753,77.62,BBH,-1.64167,0.213352,0.00574527,1.04382 gb1_A274Q,gb1_274,gb1,gb1,P06654,1.04382,NO,274,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.728,-3.411,1.683,,,,,,,4.162,4.162,11.83,AHP,-1.81767,0.177985,0.0068419,1.04382 beta-lactamase_39_A282W,beta-lactamase_39_282,TEM-1,beta-lactamase_39,P62593,1.04392,NO,282,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.0495842,0.0449821,1.04392 PSD95pdz3_N326S,PSD95pdz3_326,PSD95pdz3,PSD95pdz3,P31016,1.04392,NO,326,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-1.41,-2.617,1.207,5.52537,,,,,19.0688,,,,HPH,-1.52133,0.0758425,0.00101078,1.04392 beta-lactamase_0_E61W,beta-lactamase_0_61,TEM-1,beta-lactamase_0,P62593,1.04399,NO,61,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.115,-5.544,3.429,,0.775,T,a,1.04,1.29,34.763,34.763,77.62,OAA,-1.92567,0.0500837,0.00440955,1.04399 beta-lactamase_39_L188N,beta-lactamase_39_188,TEM-1,beta-lactamase_39,P62593,1.04401,NO,188,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.166,-4.122,2.956,,,H,A,0.55,-0.3,2.982,,60.14,PHB,-1.47033,0.0495842,0.00295687,1.04401 PSD95pdz3_A370K,PSD95pdz3_370,PSD95pdz3,PSD95pdz3,P31016,1.04402,NO,370,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.307,-3.139,1.832,5.22304,,,,,17.284,,,,PHP,-1.57967,0.0758425,0.000429106,1.04402 beta-lactamase_156_A183N,beta-lactamase_156_183,TEM-1,beta-lactamase_156,P62593,1.04403,NO,183,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.231,-2.504,1.273,,0.155,H,A,0.46,-0.91,23.859,23.859,77.62,HHH,-1.53367,0.111618,0.00296631,1.04403 beta-lactamase_D33H,beta-lactamase_33,TEM-1,beta-lactamase,P62593,1.04403,NO,33,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.321,-4.654,2.333,5.05203,0.366,H,A,0.23,0.33,2.032,,77.62,BAH,-2.12133,0.221079,0.00435556,1.04403 beta-lactamase_39_A282D,beta-lactamase_39_282,TEM-1,beta-lactamase_39,P62593,1.04405,NO,282,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.0495842,0.0449821,1.04405 kka2_1:8_R44L,kka2_1:8_44,Kka2,kka2_1:8,P00552,1.04407,NO,44,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.062,-2.371,0.309,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.100394,0.00745043,1.04407 kka2_1:8_R44L,kka2_1:8_44,Kka2,kka2_1:8,P00552,1.04407,NO,44,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.062,-2.371,0.309,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.100394,0.00745043,1.04407 beta-lactamase_625_V106Y,beta-lactamase_625_106,TEM-1,beta-lactamase_625,P62593,1.04408,NO,106,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.218,-3.895,2.677,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.213352,0.00304168,1.04408 beta-lactamase_625_R202I,beta-lactamase_625_202,TEM-1,beta-lactamase_625,P62593,1.04409,NO,202,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.292,-4.027,2.735,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.213352,0.00321899,1.04409 PSD95pdz3_D366G,PSD95pdz3_366,PSD95pdz3,PSD95pdz3,P31016,1.0441,NO,366,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.264,-2.815,1.551,5.55684,,,,,20.2375,,,,HAH,-1.401,0.0758425,0.000481272,1.0441 beta-lactamase_625_F58K,beta-lactamase_625_58,TEM-1,beta-lactamase_625,P62593,1.04417,NO,58,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-2.914,-3.623,0.709,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.213352,0.00523369,1.04417 beta-lactamase_0_L135Y,beta-lactamase_0_135,TEM-1,beta-lactamase_0,P62593,1.04418,NO,135,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.002,-3.991,2.989,,0.117,H,A,0.55,-0.58,0.705,,43.71,PHH,-1.03767,0.0500837,0.00244423,1.04418 beta-lactamase_625_V106A,beta-lactamase_625_106,TEM-1,beta-lactamase_625,P62593,1.04418,NO,106,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.218,-3.084,1.866,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.213352,0.00304168,1.04418 beta-lactamase_K213A,beta-lactamase_213,TEM-1,beta-lactamase,P62593,1.04418,NO,213,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.81,-3.194,1.384,5.63167,0.67,,A,1.59,0.29,3.924,,67.83,ABH,-1.57767,0.221079,0.00610411,1.04418 beta-lactamase_0_E62S,beta-lactamase_0_62,TEM-1,beta-lactamase_0,P62593,1.04419,NO,62,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.193,-3.245,2.052,,0.342,S,B,1.04,-0.3,5.784,,73.08,AAB,-1.417,0.0500837,0.00264802,1.04419 beta-lactamase_2500_A211D,beta-lactamase_2500_211,TEM-1,beta-lactamase_2500,P62593,1.0442,NO,211,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.896,-1.934,0.038,,0.369,T,A,0.46,-0.69,2.061,,77.62,AHA,-1.94633,0.361275,0.00648183,1.0442 beta-lactamase_0_A182T,beta-lactamase_0_182,TEM-1,beta-lactamase_0,P62593,1.04424,NO,182,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.777,-2.685,0.908,,0.136,H,A,0.46,-0.66,10.765,10.765,93.01,OHH,-1.27367,0.0500837,0.00559099,1.04424 beta-lactamase_625_K190I,beta-lactamase_625_190,TEM-1,beta-lactamase_625,P62593,1.04425,NO,190,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.994,-3.984,1.99,,0.371,H,A,2.34,0.16,29.753,29.753,77.62,BBH,-1.64167,0.213352,0.00574527,1.04425 kka2_1:8_D134V,kka2_1:8_134,Kka2,kka2_1:8,P00552,1.04426,NO,134,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.969,-3.724,2.755,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.100394,0.00270812,1.04426 kka2_1:8_D134V,kka2_1:8_134,Kka2,kka2_1:8,P00552,1.04426,NO,134,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.969,-3.724,2.755,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.100394,0.00270812,1.04426 beta-lactamase_39_R239I,beta-lactamase_39_239,TEM-1,beta-lactamase_39,P62593,1.0443,NO,239,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.0495842,0.00213852,1.0443 kka2_1:4_P12R,kka2_1:4_12,Kka2,kka2_1:4,P00552,1.04432,NO,12,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.853,-3.931,3.078,,,,B,0.52,1.25,0.843,,48.11,POH,-1.80767,0.168804,0.00500011,1.04432 beta-lactamase_39_F149T,beta-lactamase_39_149,TEM-1,beta-lactamase_39,P62593,1.04434,NO,149,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.299,-3.669,2.37,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.0495842,0.00418462,1.04434 kka2_1:4_Q27R,kka2_1:4_27,Kka2,kka2_1:4,P00552,1.04435,NO,27,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-1.659,-3.828,2.169,,0.608,,A,0.4,0.71,1.498,,65.53,PPP,-1.90733,0.168804,0.00595365,1.04435 gb1_V255C,gb1_255,gb1,gb1,P06654,1.04443,NO,255,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-3.127,-4.654,1.527,,,,,,,1.323,,45.54,BHH,-2.03867,0.177985,0.00408354,1.04443 kka2_1:8_P132A,kka2_1:8_132,Kka2,kka2_1:8,P00552,1.04443,NO,132,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.775,-3.073,2.298,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.100394,0.0018489,1.04443 kka2_1:8_P132A,kka2_1:8_132,Kka2,kka2_1:8,P00552,1.04443,NO,132,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.775,-3.073,2.298,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.100394,0.0018489,1.04443 beta-lactamase_156_T138M,beta-lactamase_156_138,TEM-1,beta-lactamase_156,P62593,1.04448,NO,138,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.506,-4.821,2.315,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.111618,0.00487868,1.04448 beta-lactamase_156_R118Q,beta-lactamase_156_118,TEM-1,beta-lactamase_156,P62593,1.04463,NO,118,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.413,-3.932,1.519,,0.457,H,A,1.2,1.39,2.231,,77.62,HBA,-1.785,0.111618,0.00538794,1.04463 beta-lactamase_2500_E210C,beta-lactamase_2500_210,TEM-1,beta-lactamase_2500,P62593,1.04463,NO,210,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.319,-4.991,2.672,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.361275,0.00663582,1.04463 kka2_1:8_E235G,kka2_1:8_235,Kka2,kka2_1:8,P00552,1.04463,NO,235,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.955,-2.889,0.934,,0.631,H,A,1.52,0.12,,,65.53,OAH,-2.07267,0.100394,0.0102806,1.04463 kka2_1:8_E235G,kka2_1:8_235,Kka2,kka2_1:8,P00552,1.04463,NO,235,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.955,-2.889,0.934,,0.631,H,A,1.52,0.12,,,65.53,OAH,-2.07267,0.100394,0.0102806,1.04463 kka2_1:8_Q136M,kka2_1:8_136,Kka2,kka2_1:8,P00552,1.04463,NO,136,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-3.021,-4.715,1.694,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.100394,0.00624149,1.04463 kka2_1:8_Q136M,kka2_1:8_136,Kka2,kka2_1:8,P00552,1.04463,NO,136,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-3.021,-4.715,1.694,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.100394,0.00624149,1.04463 beta-lactamase_0_T269Y,beta-lactamase_0_269,TEM-1,beta-lactamase_0,P62593,1.04472,NO,269,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.0500837,0.00950944,1.04472 PSD95pdz3_L342I,PSD95pdz3_342,PSD95pdz3,PSD95pdz3,P31016,1.04473,NO,342,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.347,-2.567,1.22,5.03015,,,,,12.0762,,,,HHH,-1.428,0.0758425,0.00081112,1.04473 beta-lactamase_T186E,beta-lactamase_186,TEM-1,beta-lactamase,P62593,1.04474,NO,186,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.522,-2.494,-0.028,5.07364,0.396,H,A,0.3,-0.28,2.144,,77.62,HPP,-1.77633,0.221079,0.00485034,1.04474 beta-lactamase_39_F228R,beta-lactamase_39_228,TEM-1,beta-lactamase_39,P62593,1.04482,NO,228,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-2.342,-2.044,-0.298,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.0495842,0.0046669,1.04482 PSD95pdz3_Q358N,PSD95pdz3_358,PSD95pdz3,PSD95pdz3,P31016,1.04484,NO,358,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-1.699,-3.13,1.431,5.21282,,,,,14.8844,,,,APH,-1.531,0.0758425,0.000594893,1.04484 beta-lactamase_0_D155Q,beta-lactamase_0_155,TEM-1,beta-lactamase_0,P62593,1.04489,NO,155,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.889,-3.667,2.778,,0.049,,B,0.75,-0.9,16.833,16.833,64.69,OAB,-1.62267,0.0500837,0.00135315,1.04489 kka2_1:8_P12I,kka2_1:8_12,Kka2,kka2_1:8,P00552,1.0449,NO,12,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.853,-3.96,3.107,,,.,B,0.52,1.25,2.41,,48.11,POH,-1.80767,0.100394,0.00500011,1.0449 kka2_1:8_P12I,kka2_1:8_12,Kka2,kka2_1:8,P00552,1.0449,NO,12,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.853,-3.96,3.107,,,.,B,0.52,1.25,2.41,,48.11,POH,-1.80767,0.100394,0.00500011,1.0449 beta-lactamase_0_L100F,beta-lactamase_0_100,TEM-1,beta-lactamase_0,P62593,1.04494,NO,100,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.218,-3.677,2.459,,0.343,,B,0.55,0.13,1.373,,63.29,AHH,-1.23467,0.0500837,0.00413885,1.04494 kka2_1:4_E231K,kka2_1:4_231,Kka2,kka2_1:4,P00552,1.04498,NO,231,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.002,-3.423,1.421,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.168804,0.00732383,1.04498 kka2_1:8_I246R,kka2_1:8_246,Kka2,kka2_1:8,P00552,1.045,NO,246,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-2.008,-3.32,1.312,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.100394,0.0139479,1.045 kka2_1:8_I246R,kka2_1:8_246,Kka2,kka2_1:8,P00552,1.045,NO,246,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-2.008,-3.32,1.312,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.100394,0.0139479,1.045 gb1_A274L,gb1_274,gb1,gb1,P06654,1.04504,NO,274,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.728,-3.298,1.57,,,,,,,4.162,4.162,11.83,AHP,-1.81767,0.177985,0.0068419,1.04504 E1_Ubiquitin_T68A,E1_Ubiquitin_68,Uba1,E1_Ubiquitin,P0CG63,1.04509,NO,68,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,,,,,,,,,,,,,OPH,-1.039,0.18783,0.00314321,1.04509 kka2_1:8_A150D,kka2_1:8_150,Kka2,kka2_1:8,P00552,1.04519,NO,150,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.949,-3.619,2.67,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.100394,0.0045009,1.04519 kka2_1:8_A150D,kka2_1:8_150,Kka2,kka2_1:8,P00552,1.04519,NO,150,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.949,-3.619,2.67,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.100394,0.0045009,1.04519 beta-lactamase_0_R273N,beta-lactamase_0_273,TEM-1,beta-lactamase_0,P62593,1.0452,NO,273,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.314,-3.744,1.43,,0.564,H,A,1.2,1.57,20.248,20.248,73.78,ABP,-1.841,0.0500837,0.0077952,1.0452 beta-lactamase_39_L55V,beta-lactamase_39_55,TEM-1,beta-lactamase_39,P62593,1.04523,NO,55,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.86,-2.346,0.486,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.0495842,0.00403741,1.04523 beta-lactamase_39_H110V,beta-lactamase_39_110,TEM-1,beta-lactamase_39,P62593,1.04525,NO,110,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-1.706,-3.735,2.029,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.0495842,0.00441499,1.04525 kka2_1:2_A150W,kka2_1:2_150,Kka2,kka2_1:2,P00552,1.04527,NO,150,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.949,-5.375,4.426,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.295029,0.0045009,1.04527 beta-lactamase_0_A132G,beta-lactamase_0_132,TEM-1,beta-lactamase_0,P62593,1.04528,NO,132,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.9,-3.009,2.109,,,H,A,0.46,-0.93,2.249,,64.69,PHH,-1.138,0.0500837,0.000962524,1.04528 beta-lactamase_0_L100T,beta-lactamase_0_100,TEM-1,beta-lactamase_0,P62593,1.04528,NO,100,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.218,-3.502,2.284,,0.343,,B,0.55,0.13,1.373,,63.29,AHH,-1.23467,0.0500837,0.00413885,1.04528 gb1_Q228T,gb1_228,gb1,gb1,P06654,1.04528,NO,228,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,,-3.777,2.001,,,,,,,,,,OPH,-1.282,0.177985,0.00391043,1.04528 beta-lactamase_0_T179H,beta-lactamase_0_179,TEM-1,beta-lactamase_0,P62593,1.04529,NO,179,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.085,-2.971,1.886,,,E,B,0.22,-1.38,0.367,,73.08,PPH,-1.557,0.0500837,0.00226045,1.04529 beta-lactamase_156_L150M,beta-lactamase_156_150,TEM-1,beta-lactamase_156,P62593,1.0453,NO,150,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.326,-2.392,1.066,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.111618,0.00463171,1.0453 PSD95pdz3_S350A,PSD95pdz3_350,PSD95pdz3,PSD95pdz3,P31016,1.0453,NO,350,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.519,-2.309,0.79,4.97629,,,,,25.01,,,,HPO,-1.29133,0.0758425,0.000704883,1.0453 beta-lactamase_D36K,beta-lactamase_36,TEM-1,beta-lactamase,P62593,1.04531,NO,36,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.732,-2.543,-0.189,5.39764,0.555,H,A,0.11,1.17,13.689,13.689,77.62,AAP,-1.91167,0.221079,0.00476483,1.04531 beta-lactamase_L199G,beta-lactamase_199,TEM-1,beta-lactamase,P62593,1.04531,NO,199,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-2.942,-2.663,-0.279,5.57712,0.832,H,A,0.82,0.42,15.302,15.302,77.62,PHH,-2.32933,0.221079,0.0048649,1.04531 beta-lactamase_T193K,beta-lactamase_193,TEM-1,beta-lactamase,P62593,1.04531,NO,193,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.914,-3.726,1.812,5.67952,0.439,H,a,0.3,0.33,1.863,,63.99,HPO,-1.52133,0.221079,0.00482669,1.04531 PSD95pdz3_T387C,PSD95pdz3_387,PSD95pdz3,PSD95pdz3,P31016,1.04531,NO,387,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.391,-4.319,2.928,5.20757,,,,,18.8043,,,,HPH,-1.49533,0.0758425,0.000167911,1.04531 kka2_1:8_P76L,kka2_1:8_76,Kka2,kka2_1:8,P00552,1.04532,NO,76,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.449,-2.705,1.256,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.100394,0.00625685,1.04532 kka2_1:8_P76L,kka2_1:8_76,Kka2,kka2_1:8,P00552,1.04532,NO,76,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.449,-2.705,1.256,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.100394,0.00625685,1.04532 PSD95pdz3_Q358H,PSD95pdz3_358,PSD95pdz3,PSD95pdz3,P31016,1.04532,NO,358,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-1.699,-3.912,2.213,5.21282,,,,,14.8844,,,,APH,-1.531,0.0758425,0.000594893,1.04532 PSD95pdz3_G356A,PSD95pdz3_356,PSD95pdz3,PSD95pdz3,P31016,1.04533,NO,356,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.008,-2.534,1.526,4.8656,,,,,11.9575,,,,BOA,-1.22933,0.0758425,0.000623061,1.04533 kka2_1:4_A108M,kka2_1:4_108,Kka2,kka2_1:4,P00552,1.04539,NO,108,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.061,-4.804,2.743,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.168804,0.00751209,1.04539 WW_domain_P172A,WW_domain_172,Yap65,WW_domain,P46937,1.0454,NO,172,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.035,-2.855,1.82,,,,,,,,,,HOH,-1.233,0.153962,0.000991485,1.0454 Pab1_N192E,Pab1_192,Pab1,Pab1,P04147,1.04544,NO,192,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-1.079,-3.032,1.953,,0.619,T,l,,2.28,,,,HPO,-1.231,0.175299,0.000273498,1.04544 beta-lactamase_39_G226E,beta-lactamase_39_226,TEM-1,beta-lactamase_39,P62593,1.04545,NO,226,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.461,-2.776,1.315,,0.701,T,l,0.29,-0.25,23.034,23.034,74.48,HOH,-1.42933,0.0495842,0.00665294,1.04545 kka2_1:8_T130N,kka2_1:8_130,Kka2,kka2_1:8,P00552,1.04545,NO,130,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.392,-2.756,0.364,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.100394,0.00804204,1.04545 kka2_1:8_T130N,kka2_1:8_130,Kka2,kka2_1:8,P00552,1.04545,NO,130,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.392,-2.756,0.364,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.100394,0.00804204,1.04545 kka2_1:8_W15L,kka2_1:8_15,Kka2,kka2_1:8,P00552,1.04546,NO,15,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-1.392,-1.643,0.251,,0.01,G,A,1.51,0.15,0.827,,52.27,HHH,-2.10533,0.100394,0.00585505,1.04546 kka2_1:8_W15L,kka2_1:8_15,Kka2,kka2_1:8,P00552,1.04546,NO,15,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-1.392,-1.643,0.251,,0.01,G,A,1.51,0.15,0.827,,52.27,HHH,-2.10533,0.100394,0.00585505,1.04546 beta-lactamase_2500_E210H,beta-lactamase_2500_210,TEM-1,beta-lactamase_2500,P62593,1.04547,NO,210,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.319,-4.778,2.459,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.361275,0.00663582,1.04547 PSD95pdz3_N326W,PSD95pdz3_326,PSD95pdz3,PSD95pdz3,P31016,1.04547,NO,326,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-1.41,-5.229,3.819,5.52537,,,,,19.0688,,,,HPH,-1.52133,0.0758425,0.00101078,1.04547 beta-lactamase_0_A84T,beta-lactamase_0_84,TEM-1,beta-lactamase_0,P62593,1.04549,NO,84,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.651,-2.88,1.229,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.0500837,0.00503822,1.04549 beta-lactamase_0_H94P,beta-lactamase_0_94,TEM-1,beta-lactamase_0,P62593,1.04551,NO,94,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-2.5,-2.499,-0.001,,0.776,,B,0.17,1.24,1.176,,77.62,HBH,-1.872,0.0500837,0.00389226,1.04551 beta-lactamase_39_T131N,beta-lactamase_39_131,TEM-1,beta-lactamase_39,P62593,1.04553,NO,131,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.328,-3.603,2.275,,,H,A,0.22,-0.69,3.306,,67.48,PPH,-1.00867,0.0495842,0.00345886,1.04553 kka2_1:4_G164S,kka2_1:4_164,Kka2,kka2_1:4,P00552,1.04553,NO,164,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.869,-2.388,1.519,,0.862,T,l,0.75,1.45,1.539,,64.39,POH,-1.828,0.168804,0.00442091,1.04553 beta-lactamase_0_S51N,beta-lactamase_0_51,TEM-1,beta-lactamase_0,P62593,1.04555,NO,51,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.526,-2.556,1.03,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.0500837,0.00504821,1.04555 PSD95pdz3_V315E,PSD95pdz3_315,PSD95pdz3,PSD95pdz3,P31016,1.04556,NO,315,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.625,-3.627,2.002,5.52024,,,,,18.4557,4.054,,81.35,HHH,-1.62767,0.0758425,0.00153536,1.04556 beta-lactamase_0_Q37L,beta-lactamase_0_37,TEM-1,beta-lactamase_0,P62593,1.04557,NO,37,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.134,-2.893,0.759,,0.613,H,A,0.64,1.98,4.001,,73.08,APH,-2.06967,0.0500837,0.00425833,1.04557 PSD95pdz3_Q358R,PSD95pdz3_358,PSD95pdz3,PSD95pdz3,P31016,1.04559,NO,358,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-1.699,-2.94,1.241,5.21282,,,,,14.8844,,,,APH,-1.531,0.0758425,0.000594893,1.04559 kka2_1:8_P194A,kka2_1:8_194,Kka2,kka2_1:8,P00552,1.0456,NO,194,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.846,-3.118,2.272,,0.308,G,A,0.52,-1.19,4.861,,53.03,HOP,-0.888333,0.100394,0.00314194,1.0456 kka2_1:8_P194A,kka2_1:8_194,Kka2,kka2_1:8,P00552,1.0456,NO,194,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.846,-3.118,2.272,,0.308,G,A,0.52,-1.19,4.861,,53.03,HOP,-0.888333,0.100394,0.00314194,1.0456 beta-lactamase_0_T179E,beta-lactamase_0_179,TEM-1,beta-lactamase_0,P62593,1.04564,NO,179,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.085,-3.446,2.361,,,E,B,0.22,-1.38,0.367,,73.08,PPH,-1.557,0.0500837,0.00226045,1.04564 beta-lactamase_39_T112I,beta-lactamase_39_112,TEM-1,beta-lactamase_39,P62593,1.04565,NO,112,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.186,-3.949,1.763,,0.921,T,A,0.22,1.06,2.87,,73.78,HPA,-1.925,0.0495842,0.00531334,1.04565 beta-lactamase_39_L38N,beta-lactamase_39_38,TEM-1,beta-lactamase_39,P62593,1.04571,NO,38,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.343,-4.007,2.664,,0.088,H,A,0.55,0.2,17.089,17.089,64.34,PHO,-1.78033,0.0495842,0.00373244,1.04571 PSD95pdz3_S320W,PSD95pdz3_320,PSD95pdz3,PSD95pdz3,P31016,1.04572,NO,320,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.519,-5.004,3.485,5.81757,,,,,21.4517,,,,OPP,-1.306,0.0758425,0.00108158,1.04572 kka2_1:8_A168E,kka2_1:8_168,Kka2,kka2_1:8,P00552,1.04573,NO,168,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.989,-2.167,0.178,,0.67,H,A,0.46,0.15,11.329,11.329,64.39,OHA,-2.12933,0.100394,0.00806773,1.04573 kka2_1:8_A168E,kka2_1:8_168,Kka2,kka2_1:8,P00552,1.04573,NO,168,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.989,-2.167,0.178,,0.67,H,A,0.46,0.15,11.329,11.329,64.39,OHA,-2.12933,0.100394,0.00806773,1.04573 beta-lactamase_0_D129V,beta-lactamase_0_129,TEM-1,beta-lactamase_0,P62593,1.04574,NO,129,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.816,-3.751,2.935,,,,B,0.75,-0.69,2.66,,34.97,PAP,-0.818,0.0500837,0.00109178,1.04574 beta-lactamase_156_E272D,beta-lactamase_156_272,TEM-1,beta-lactamase_156,P62593,1.04574,NO,272,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.111618,0.00545371,1.04574 beta-lactamase_39_E61Q,beta-lactamase_39_61,TEM-1,beta-lactamase_39,P62593,1.04574,NO,61,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.115,-2.702,0.587,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.0495842,0.00440955,1.04574 kka2_1:8_Q252A,kka2_1:8_252,Kka2,kka2_1:8,P00552,1.04574,NO,252,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.63,-2.051,-0.579,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.100394,0.0121001,1.04574 kka2_1:8_Q252A,kka2_1:8_252,Kka2,kka2_1:8,P00552,1.04574,NO,252,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.63,-2.051,-0.579,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.100394,0.0121001,1.04574 beta-lactamase_0_G39L,beta-lactamase_0_39,TEM-1,beta-lactamase_0,P62593,1.04575,NO,39,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.864,-3.751,1.887,,0.701,T,L,0.29,0.47,4.111,,77.62,HOH,-1.53633,0.0500837,0.00487611,1.04575 beta-lactamase_39_G194R,beta-lactamase_39_194,TEM-1,beta-lactamase_39,P62593,1.04577,NO,194,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.396,-3.912,2.516,,0.276,S,b,0.29,0.36,4.852,,67.83,POA,-1.832,0.0495842,0.00392163,1.04577 beta-lactamase_39_E145C,beta-lactamase_39_145,TEM-1,beta-lactamase_39,P62593,1.04578,NO,145,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.357,-5.044,2.687,,0.545,H,A,1.04,0.79,1.199,,77.62,BAH,-2.069,0.0495842,0.00553285,1.04578 kka2_1:8_I29K,kka2_1:8_29,Kka2,kka2_1:8,P00552,1.0458,NO,29,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.692,-3.779,2.087,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.100394,0.00619521,1.0458 kka2_1:8_I29K,kka2_1:8_29,Kka2,kka2_1:8,P00552,1.0458,NO,29,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.692,-3.779,2.087,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.100394,0.00619521,1.0458 PSD95pdz3_V365T,PSD95pdz3_365,PSD95pdz3,PSD95pdz3,P31016,1.0458,NO,365,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.592,-2.973,1.381,5.03791,,,,,18.9657,2.364,,81.35,OHA,-1.288,0.0758425,0.000649764,1.0458 beta-lactamase_0_R162A,beta-lactamase_0_162,TEM-1,beta-lactamase_0,P62593,1.04586,NO,162,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.016,-3.127,2.111,,0.124,S,B,1.2,-0.37,1.026,,64.69,ABH,-1.25,0.0500837,0.000561334,1.04586 beta-lactamase_2500_K190E,beta-lactamase_2500_190,TEM-1,beta-lactamase_2500,P62593,1.04587,NO,190,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.994,-3.44,1.446,,0.371,H,A,2.34,0.16,29.753,29.753,77.62,BBH,-1.64167,0.361275,0.00574527,1.04587 beta-lactamase_H94I,beta-lactamase_94,TEM-1,beta-lactamase,P62593,1.04587,NO,94,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-2.5,-2.913,0.413,6.1507,0.776,,B,0.63,1.24,1.176,,77.62,HBH,-1.872,0.221079,0.00389226,1.04587 kka2_1:8_G99T,kka2_1:8_99,Kka2,kka2_1:8,P00552,1.04588,NO,99,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.596,-3.675,3.079,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.100394,0.00186055,1.04588 kka2_1:8_G99T,kka2_1:8_99,Kka2,kka2_1:8,P00552,1.04588,NO,99,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.596,-3.675,3.079,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.100394,0.00186055,1.04588 gb1_K230L,gb1_230,gb1,gb1,P06654,1.04589,NO,230,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.701,-3.05,1.349,,,,,,,0.166,,11.83,HBH,-1.52867,0.177985,0.00331703,1.04589 WW_domain_R187R,WW_domain_187,Yap65,WW_domain,P46937,1.04589,NO,187,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.402,-1.402,0,5.05189,,,,,,3.431,,78.57,PBH,-1.362,0.153962,0.00171149,1.04589 kka2_1:2_L103Q,kka2_1:2_103,Kka2,kka2_1:2,P00552,1.04595,NO,103,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-2.362,-4.06,1.698,,0.394,T,A,0.55,-0.99,3.499,,63.64,HHP,-1.534,0.295029,0.00574792,1.04595 beta-lactamase_156_K254D,beta-lactamase_156_254,TEM-1,beta-lactamase_156,P62593,1.04596,NO,254,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.111618,0.00369,1.04596 kka2_1:2_D134Q,kka2_1:2_134,Kka2,kka2_1:2,P00552,1.04599,NO,134,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.969,-3.77,2.801,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.295029,0.00270812,1.04599 gb1_Q228K,gb1_228,gb1,gb1,P06654,1.04601,NO,228,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,,,,,,,,,,,,,OPH,-1.282,0.177985,0.00391043,1.04601 beta-lactamase_0_P224F,beta-lactamase_0_224,TEM-1,beta-lactamase_0,P62593,1.04606,NO,224,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.893,-4.486,3.593,,0.383,,B,0.52,-0.3,3.587,,74.48,HOH,-1.26433,0.0500837,0.00189564,1.04606 beta-lactamase_39_S283K,beta-lactamase_39_283,TEM-1,beta-lactamase_39,P62593,1.04608,NO,283,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.0495842,0.0429138,1.04608 beta-lactamase_39_R273D,beta-lactamase_39_273,TEM-1,beta-lactamase_39,P62593,1.04609,NO,273,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.314,-3.543,1.229,,0.564,H,A,1.2,1.57,2.163,,73.78,ABP,-1.841,0.0495842,0.0077952,1.04609 kka2_1:8_D156E,kka2_1:8_156,Kka2,kka2_1:8,P00552,1.04609,NO,156,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.696,-2.041,0.345,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.100394,0.00926998,1.04609 kka2_1:8_D156E,kka2_1:8_156,Kka2,kka2_1:8,P00552,1.04609,NO,156,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.696,-2.041,0.345,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.100394,0.00926998,1.04609 PSD95pdz3_R354L,PSD95pdz3_354,PSD95pdz3,PSD95pdz3,P31016,1.04609,NO,354,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.582,-3.04,1.458,6.21887,,,,,23.7791,,,,HBB,-1.44833,0.0758425,0.000650924,1.04609 beta-lactamase_0_H156P,beta-lactamase_0_156,TEM-1,beta-lactamase_0,P62593,1.0461,NO,156,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-3.156,-2.552,-0.604,,0.753,S,A,0.17,-0.6,23.367,23.367,77.62,ABH,-1.932,0.0500837,0.00468596,1.0461 beta-lactamase_39_E26H,beta-lactamase_39_26,TEM-1,beta-lactamase_39,P62593,1.04613,NO,26,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.454,-4.609,2.155,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.0495842,0.00297948,1.04613 beta-lactamase_39_R118C,beta-lactamase_39_118,TEM-1,beta-lactamase_39,P62593,1.04613,NO,118,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.413,-4.992,2.579,,0.457,H,A,1.2,1.39,3.961,,77.62,HBA,-1.785,0.0495842,0.00538794,1.04613 beta-lactamase_39_E26L,beta-lactamase_39_26,TEM-1,beta-lactamase_39,P62593,1.04617,NO,26,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.454,-2.726,0.272,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.0495842,0.00297948,1.04617 kka2_1:2_Q42G,kka2_1:2_42,Kka2,kka2_1:2,P00552,1.04617,NO,42,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.907,-2.492,-0.415,,1.044,T,B,0.64,-0.8,2.792,,71.59,HPO,-2.12433,0.295029,0.00679212,1.04617 beta-lactamase_0_V29Y,beta-lactamase_0_29,TEM-1,beta-lactamase_0,P62593,1.04621,NO,29,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-2.856,-4.329,1.473,,0.733,H,A,0.44,-0.78,21.916,21.916,93.01,HHB,-2.24733,0.0500837,0.00318969,1.04621 PSD95pdz3_L360I,PSD95pdz3_360,PSD95pdz3,PSD95pdz3,P31016,1.04624,NO,360,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.431,-2.746,1.315,5.09284,,,,,14.2425,1.419,,86.88,HHP,-1.52667,0.0758425,0.000770471,1.04624 gb1_K276R,gb1_276,gb1,gb1,P06654,1.04625,NO,276,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.456,-1.77,0.314,,,,,,,0.236,,12.72,PBP,-1.65133,0.177985,0.00620493,1.04625 beta-lactamase_E237M,beta-lactamase_237,TEM-1,beta-lactamase,P62593,1.04626,NO,237,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.058,-4.836,2.778,5.42877,0.583,S,B,1.62,1.2,2.144,,77.62,OAB,-1.61467,0.221079,0.0048626,1.04626 beta-lactamase_0_C75S,beta-lactamase_0_75,TEM-1,beta-lactamase_0,P62593,1.04628,NO,75,C,S,CS,Special,Polar,5.07,5.68,0.61,112,121,105,-16,108.5,89,-19.5,-1.245,-2.597,1.352,,,H,A,0.46,-0.87,2.256,,50,HOO,-1.24333,0.0500837,0.0034616,1.04628 beta-lactamase_39_A211Q,beta-lactamase_39_211,TEM-1,beta-lactamase_39,P62593,1.04629,NO,211,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.896,-3.096,1.2,,0.369,T,A,0.46,-0.69,1.419,,77.62,AHA,-1.94633,0.0495842,0.00648183,1.04629 kka2_1:8_L19W,kka2_1:8_19,Kka2,kka2_1:8,P00552,1.04629,NO,19,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.254,-5.02,3.766,,0.08,T,A,1.59,-0.26,2.044,,65.53,BHH,-2.221,0.100394,0.00620703,1.04629 kka2_1:8_L19W,kka2_1:8_19,Kka2,kka2_1:8,P00552,1.04629,NO,19,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.254,-5.02,3.766,,0.08,T,A,1.59,-0.26,2.044,,65.53,BHH,-2.221,0.100394,0.00620703,1.04629 beta-lactamase_0_I244R,beta-lactamase_0_244,TEM-1,beta-lactamase_0,P62593,1.0463,NO,244,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.555,-4.183,2.628,,,E,B,0.48,-0.84,1.241,,77.62,OHH,-1.385,0.0500837,0.00605379,1.0463 kka2_1:8_A71Y,kka2_1:8_71,Kka2,kka2_1:8,P00552,1.04632,NO,71,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.824,-4.36,2.536,,0.553,H,A,0.46,0.08,18.64,18.64,64.39,HHP,-1.74033,0.100394,0.00727707,1.04632 kka2_1:8_A71Y,kka2_1:8_71,Kka2,kka2_1:8,P00552,1.04632,NO,71,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.824,-4.36,2.536,,0.553,H,A,0.46,0.08,18.64,18.64,64.39,HHP,-1.74033,0.100394,0.00727707,1.04632 beta-lactamase_0_Q86W,beta-lactamase_0_86,TEM-1,beta-lactamase_0,P62593,1.04633,NO,86,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.4,-5.489,3.089,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.0500837,0.00450027,1.04633 beta-lactamase_0_H156S,beta-lactamase_0_156,TEM-1,beta-lactamase_0,P62593,1.04637,NO,156,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-3.156,-2.584,-0.572,,0.753,S,A,0.17,-0.6,23.367,23.367,77.62,ABH,-1.932,0.0500837,0.00468596,1.04637 beta-lactamase_0_I277Q,beta-lactamase_0_277,TEM-1,beta-lactamase_0,P62593,1.04638,NO,277,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.0500837,0.0169305,1.04638 kka2_1:2_D154R,kka2_1:2_154,Kka2,kka2_1:2,P00552,1.04639,NO,154,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.876,-3.899,3.023,,0.457,,b,0.29,1.48,3.631,,52.65,HAP,-1.52467,0.295029,0.00292633,1.04639 beta-lactamase_0_L135G,beta-lactamase_0_135,TEM-1,beta-lactamase_0,P62593,1.04641,NO,135,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.002,-3.837,2.835,,0.117,H,A,0.55,-0.58,0.705,,43.71,PHH,-1.03767,0.0500837,0.00244423,1.04641 beta-lactamase_0_K53F,beta-lactamase_0_53,TEM-1,beta-lactamase_0,P62593,1.04642,NO,53,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-2.313,-4.249,1.936,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.0500837,0.00383383,1.04642 beta-lactamase_39_E26C,beta-lactamase_39_26,TEM-1,beta-lactamase_39,P62593,1.04642,NO,26,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.454,-5.02,2.566,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.0495842,0.00297948,1.04642 beta-lactamase_39_F149I,beta-lactamase_39_149,TEM-1,beta-lactamase_39,P62593,1.04642,NO,149,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-1.299,-3.576,2.277,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.0495842,0.00418462,1.04642 PSD95pdz3_N369I,PSD95pdz3_369,PSD95pdz3,PSD95pdz3,P31016,1.04651,NO,369,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-1.572,-3.691,2.119,5.91569,,,,,24.1262,0.44,,87.71,BPH,-1.487,0.0758425,0.000608412,1.04651 kka2_1:4_Q26G,kka2_1:4_26,Kka2,kka2_1:4,P00552,1.04655,NO,26,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.18,-2.702,0.522,,0.448,E,B,0.4,0.44,5.022,,92.05,HPP,-2.11167,0.168804,0.00708962,1.04655 beta-lactamase_0_E166L,beta-lactamase_0_166,TEM-1,beta-lactamase_0,P62593,1.04656,NO,166,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.756,-2.872,1.116,,0.508,G,A,1.04,1.05,17.227,17.227,73.08,OAH,-1.42233,0.0500837,0.00512989,1.04656 beta-lactamase_0_L219P,beta-lactamase_0_219,TEM-1,beta-lactamase_0,P62593,1.04657,NO,219,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.313,-4.214,2.901,,,I,A,0.55,-0.51,6.513,6.513,74.48,HHB,-1.21533,0.0500837,0.00664345,1.04657 gb1_D272K,gb1_272,gb1,gb1,P06654,1.04661,NO,272,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.457,-3.136,1.679,,,,,,,0.234,,11.83,HAA,-1.54533,0.177985,0.00218257,1.04661 kka2_1:4_D156T,kka2_1:4_156,Kka2,kka2_1:4,P00552,1.04662,NO,156,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.696,-1.988,0.292,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.168804,0.00926998,1.04662 PSD95pdz3_R354K,PSD95pdz3_354,PSD95pdz3,PSD95pdz3,P31016,1.04662,NO,354,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.582,-2.464,0.882,6.21887,,,,,23.7791,,,,HBB,-1.44833,0.0758425,0.000650924,1.04662 beta-lactamase_0_K213A,beta-lactamase_0_213,TEM-1,beta-lactamase_0,P62593,1.04663,NO,213,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.81,-3.194,1.384,,0.67,,A,2.34,0.29,3.015,,67.83,ABH,-1.57767,0.0500837,0.00610411,1.04663 beta-lactamase_A15T,beta-lactamase_15,TEM-1,beta-lactamase,P62593,1.04667,NO,15,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.654,-2.063,0.409,,,,,,,31.998,31.998,93.01,HHH,-2.10833,0.221079,0.00248966,1.04667 beta-lactamase_39_R162N,beta-lactamase_39_162,TEM-1,beta-lactamase_39,P62593,1.04671,NO,162,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.016,-3.588,2.572,,0.124,S,B,1.2,-0.37,31.656,31.656,64.69,ABH,-1.25,0.0495842,0.000561334,1.04671 PSD95pdz3_R313P,PSD95pdz3_313,PSD95pdz3,PSD95pdz3,P31016,1.04671,NO,313,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.582,-3.561,1.979,6.63563,,,,,18.3955,,,,BBH,-1.59733,0.0758425,0.000840067,1.04671 kka2_1:8_D156P,kka2_1:8_156,Kka2,kka2_1:8,P00552,1.04672,NO,156,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.696,-3.904,2.208,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.100394,0.00926998,1.04672 kka2_1:8_D156P,kka2_1:8_156,Kka2,kka2_1:8,P00552,1.04672,NO,156,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.696,-3.904,2.208,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.100394,0.00926998,1.04672 beta-lactamase_0_T131C,beta-lactamase_0_131,TEM-1,beta-lactamase_0,P62593,1.04673,NO,131,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.328,-3.123,1.795,,,H,A,0.22,-0.69,3.306,,67.48,PPH,-1.00867,0.0500837,0.00345886,1.04673 PSD95pdz3_G319A,PSD95pdz3_319,PSD95pdz3,PSD95pdz3,P31016,1.04674,NO,319,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.008,-2.534,1.526,4.95387,,,,,18.8725,,,,BOP,-1.36967,0.0758425,0.00109317,1.04674 beta-lactamase_39_T186E,beta-lactamase_39_186,TEM-1,beta-lactamase_39,P62593,1.04675,NO,186,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.522,-2.494,-0.028,,0.396,H,A,0.22,-0.28,0.515,,77.62,HPP,-1.77633,0.0495842,0.00485034,1.04675 beta-lactamase_0_S221A,beta-lactamase_0_221,TEM-1,beta-lactamase_0,P62593,1.04676,NO,221,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.754,-1.332,-0.422,,0.624,H,A,0.27,-0.2,2.914,,74.48,BPH,-1.59967,0.0500837,0.0046094,1.04676 beta-lactamase_39_E26Q,beta-lactamase_39_26,TEM-1,beta-lactamase_39,P62593,1.04679,NO,26,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.454,-2.296,-0.158,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.0495842,0.00297948,1.04679 gb1_A274K,gb1_274,gb1,gb1,P06654,1.04685,NO,274,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.728,-3.129,1.401,,,,,,,4.162,4.162,11.83,AHP,-1.81767,0.177985,0.0068419,1.04685 E1_Ubiquitin_L43Y,E1_Ubiquitin_43,Uba1,E1_Ubiquitin,P0CG63,1.04686,NO,43,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.188,-3.858,2.67,,,E,B,,-1.17,,,,BHH,-1.30733,0.18783,0.00190185,1.04686 beta-lactamase_39_P250N,beta-lactamase_39_250,TEM-1,beta-lactamase_39,P62593,1.04687,NO,250,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.0495842,0.00550899,1.04687 kka2_1:8_R145S,kka2_1:8_145,Kka2,kka2_1:8,P00552,1.04687,NO,145,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.804,-2.769,0.965,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.100394,0.00846663,1.04687 kka2_1:8_R145S,kka2_1:8_145,Kka2,kka2_1:8,P00552,1.04687,NO,145,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.804,-2.769,0.965,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.100394,0.00846663,1.04687 kka2_1:8_Q27W,kka2_1:8_27,Kka2,kka2_1:8,P00552,1.0469,NO,27,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-1.659,-5.449,3.79,,0.608,.,A,0.64,0.71,3.919,,65.53,PPP,-1.90733,0.100394,0.00595365,1.0469 kka2_1:8_Q27W,kka2_1:8_27,Kka2,kka2_1:8,P00552,1.0469,NO,27,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-1.659,-5.449,3.79,,0.608,.,A,0.64,0.71,3.919,,65.53,PPP,-1.90733,0.100394,0.00595365,1.0469 beta-lactamase_39_G243C,beta-lactamase_39_243,TEM-1,beta-lactamase_39,P62593,1.04692,NO,243,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.0495842,0.00464034,1.04692 WW_domain_D170N,WW_domain_170,Yap65,WW_domain,P46937,1.04693,NO,170,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.213,-3.122,1.909,,,,,,,0.399,,15.87,OAH,-1.38,0.153962,0.00123319,1.04693 gb1_E245C,gb1_245,gb1,gb1,P06654,1.04697,NO,245,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.725,-4.823,2.098,,,,,,,0.712,,45.54,PAH,-1.84567,0.177985,0.00158611,1.04697 gb1_T275K,gb1_275,gb1,gb1,P06654,1.04697,NO,275,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.727,-3.353,1.626,,,,,,,0.511,,35.71,HPB,-1.637,0.177985,0.00606618,1.04697 beta-lactamase_0_D113F,beta-lactamase_0_113,TEM-1,beta-lactamase_0,P62593,1.04698,NO,113,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.829,-4.448,2.619,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.0500837,0.00474112,1.04698 beta-lactamase_0_A182V,beta-lactamase_0_182,TEM-1,beta-lactamase_0,P62593,1.04699,NO,182,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.777,-2.556,0.779,,0.136,H,A,0.46,-0.66,10.765,10.765,93.01,OHH,-1.27367,0.0500837,0.00559099,1.04699 beta-lactamase_39_N50M,beta-lactamase_39_50,TEM-1,beta-lactamase_39,P62593,1.04699,NO,50,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-2.979,-4.727,1.748,,0.912,T,A,0.61,1.24,10.736,,77.62,HPP,-2.134,0.0495842,0.0047211,1.04699 beta-lactamase_39_A182Q,beta-lactamase_39_182,TEM-1,beta-lactamase_39,P62593,1.04701,NO,182,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.777,-3.097,1.32,,0.136,H,A,0.46,-0.66,2.598,,93.01,OHH,-1.27367,0.0495842,0.00559099,1.04701 kka2_1:4_S68I,kka2_1:4_68,Kka2,kka2_1:4,P00552,1.04701,NO,68,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.623,-4.041,1.418,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.168804,0.00608265,1.04701 WW_domain_S183I,WW_domain_183,Yap65,WW_domain,P46937,1.04702,NO,183,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.95,-3.8,1.85,5.35576,,,,,,1.594,,83.93,PPP,-1.48733,0.153962,0.00445513,1.04702 beta-lactamase_625_D212T,beta-lactamase_625_212,TEM-1,beta-lactamase_625,P62593,1.04709,NO,212,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.624,-2.54,0.916,,0.037,,b,0.75,-0.58,1.516,,74.48,HAB,-1.77667,0.213352,0.00644302,1.04709 gb1_A274R,gb1_274,gb1,gb1,P06654,1.04709,NO,274,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.728,-3.53,1.802,,,,,,,4.162,4.162,11.83,AHP,-1.81767,0.177985,0.0068419,1.04709 beta-lactamase_0_L73I,beta-lactamase_0_73,TEM-1,beta-lactamase_0,P62593,1.0471,NO,73,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.507,-2.52,1.013,,,H,A,0.55,-0.64,0.877,,67.83,HHH,-1.487,0.0500837,0.00488983,1.0471 beta-lactamase_0_E164P,beta-lactamase_0_164,TEM-1,beta-lactamase_0,P62593,1.04713,NO,164,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-0.948,-3.725,2.777,,0.011,T,B,1.04,-0.4,1.011,,64.69,HAO,-1.388,0.0500837,0.00137286,1.04713 kka2_1:8_V97Q,kka2_1:8_97,Kka2,kka2_1:8,P00552,1.04714,NO,97,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.453,-4.252,2.799,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.100394,0.00737869,1.04714 kka2_1:8_V97Q,kka2_1:8_97,Kka2,kka2_1:8,P00552,1.04714,NO,97,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.453,-4.252,2.799,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.100394,0.00737869,1.04714 kka2_1:2_H139C,kka2_1:2_139,Kka2,kka2_1:2,P00552,1.04715,NO,139,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-2.809,-5.201,2.392,,0.471,H,A,0.87,0.68,13.912,13.912,63.64,BBB,-2.22,0.295029,0.00734779,1.04715 kka2_1:8_T146N,kka2_1:8_146,Kka2,kka2_1:8,P00552,1.04716,NO,146,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.978,-3.146,0.168,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.100394,0.00606474,1.04716 kka2_1:8_T146N,kka2_1:8_146,Kka2,kka2_1:8,P00552,1.04716,NO,146,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.978,-3.146,0.168,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.100394,0.00606474,1.04716 kka2_1:2_I29Q,kka2_1:2_29,Kka2,kka2_1:2,P00552,1.0472,NO,29,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.692,-2.968,1.276,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.295029,0.00619521,1.0472 gb1_A274V,gb1_274,gb1,gb1,P06654,1.04721,NO,274,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.728,-3.243,1.515,,,,,,,4.162,4.162,11.83,AHP,-1.81767,0.177985,0.0068419,1.04721 gb1_V255A,gb1_255,gb1,gb1,P06654,1.04721,NO,255,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-3.127,-2.041,-1.086,,,,,,,1.323,,45.54,BHH,-2.03867,0.177985,0.00408354,1.04721 kka2_1:8_A41S,kka2_1:8_41,Kka2,kka2_1:8,P00552,1.04723,NO,41,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.879,-2.842,0.963,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.100394,0.00543332,1.04723 kka2_1:8_A41S,kka2_1:8_41,Kka2,kka2_1:8,P00552,1.04723,NO,41,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.879,-2.842,0.963,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.100394,0.00543332,1.04723 beta-lactamase_39_P217K,beta-lactamase_39_217,TEM-1,beta-lactamase_39,P62593,1.04728,NO,217,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-2.062,-2.687,0.625,,0.496,I,A,0.52,-0.33,21.172,21.172,74.48,OOH,-1.64333,0.0495842,0.00463211,1.04728 kka2_1:8_K138I,kka2_1:8_138,Kka2,kka2_1:8,P00552,1.04728,NO,138,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-2.5,-3.288,0.788,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.100394,0.00628542,1.04728 kka2_1:8_K138I,kka2_1:8_138,Kka2,kka2_1:8,P00552,1.04728,NO,138,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-2.5,-3.288,0.788,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.100394,0.00628542,1.04728 beta-lactamase_0_M66K,beta-lactamase_0_66,TEM-1,beta-lactamase_0,P62593,1.04731,NO,66,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.362,-3.657,2.295,,0.013,,A,0.55,-0.7,1.204,,73.08,OHH,-1.49567,0.0500837,0.00412876,1.04731 gb1_T243H,gb1_243,gb1,gb1,P06654,1.04733,NO,243,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.415,-4.491,3.076,,,,,,,1.083,,37.28,PPP,-1.43233,0.177985,0.00308687,1.04733 PSD95pdz3_G319Q,PSD95pdz3_319,PSD95pdz3,PSD95pdz3,P31016,1.04733,NO,319,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.008,-3.806,2.798,4.95387,,,,,18.8725,,,,BOP,-1.36967,0.0758425,0.00109317,1.04733 beta-lactamase_0_Q37A,beta-lactamase_0_37,TEM-1,beta-lactamase_0,P62593,1.04739,NO,37,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.134,-2.542,0.408,,0.613,H,A,0.64,1.98,4.001,,73.08,APH,-2.06967,0.0500837,0.00425833,1.04739 beta-lactamase_39_V106I,beta-lactamase_39_106,TEM-1,beta-lactamase_39,P62593,1.04739,NO,106,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.218,-2.124,0.906,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.0495842,0.00304168,1.04739 beta-lactamase_0_A84W,beta-lactamase_0_84,TEM-1,beta-lactamase_0,P62593,1.04741,NO,84,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.651,-5.52,3.869,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.0500837,0.00503822,1.04741 kka2_1:4_D250R,kka2_1:4_250,Kka2,kka2_1:4,P00552,1.04743,NO,250,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.015,-3.871,2.856,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.168804,0.0177103,1.04743 kka2_1:2_Q61R,kka2_1:2_61,Kka2,kka2_1:2,P00552,1.04745,NO,61,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.982,-2.952,-0.03,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.295029,0.00612092,1.04745 kka2_1:8_P76C,kka2_1:8_76,Kka2,kka2_1:8,P00552,1.04747,NO,76,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.449,-5.046,3.597,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.100394,0.00625685,1.04747 kka2_1:8_P76C,kka2_1:8_76,Kka2,kka2_1:8,P00552,1.04747,NO,76,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.449,-5.046,3.597,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.100394,0.00625685,1.04747 beta-lactamase_A225M,beta-lactamase_225,TEM-1,beta-lactamase,P62593,1.04748,NO,225,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.845,-4.778,2.933,6.5181,1,T,B,0.58,-0.38,4.077,,74.48,OHO,-1.39967,0.221079,0.00465057,1.04748 beta-lactamase_A280M,beta-lactamase_280,TEM-1,beta-lactamase,P62593,1.04748,NO,280,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.708,-4.662,2.954,4.74932,0.379,H,A,0.52,-0.72,1.785,,68.18,OHP,-1.66433,0.221079,0.0530888,1.04748 beta-lactamase_D33T,beta-lactamase_33,TEM-1,beta-lactamase,P62593,1.04748,NO,33,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.321,-2.667,0.346,5.05203,0.366,H,A,0.23,0.33,2.032,,77.62,BAH,-2.12133,0.221079,0.00435556,1.04748 beta-lactamase_H156I,beta-lactamase_156,TEM-1,beta-lactamase,P62593,1.04748,NO,156,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-3.156,-4.08,0.924,6.00284,0.753,S,A,0.72,-0.6,6.456,6.456,77.62,ABH,-1.932,0.221079,0.00468596,1.04748 beta-lactamase_H24N,beta-lactamase_24,TEM-1,beta-lactamase,P62593,1.04748,NO,24,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-2.481,-3.496,1.015,5.82767,,,,,,2.708,,93.01,HBO,-1.85167,0.221079,0.00238894,1.04748 beta-lactamase_L196Q,beta-lactamase_196,TEM-1,beta-lactamase,P62593,1.04748,NO,196,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-2.478,-3.242,0.764,,0.518,S,A,0.55,1.35,,,77.62,AHH,-1.839,0.221079,0.00512144,1.04748 kka2_1:2_P12C,kka2_1:2_12,Kka2,kka2_1:2,P00552,1.04748,NO,12,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.853,-4.98,4.127,,,.,B,0.52,1.25,0.261,,48.11,POH,-1.80767,0.295029,0.00500011,1.04748 kka2_1:8_T72W,kka2_1:8_72,Kka2,kka2_1:8,P00552,1.04751,NO,72,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.38,-5.516,3.136,,0.784,H,A,0.22,0.29,3.603,,65.53,HPP,-2.238,0.100394,0.00750756,1.04751 kka2_1:8_T72W,kka2_1:8_72,Kka2,kka2_1:8,P00552,1.04751,NO,72,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.38,-5.516,3.136,,0.784,H,A,0.22,0.29,3.603,,65.53,HPP,-2.238,0.100394,0.00750756,1.04751 beta-lactamase_0_L196A,beta-lactamase_0_196,TEM-1,beta-lactamase_0,P62593,1.04752,NO,196,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-2.478,-1.974,-0.504,,0.518,S,A,0.55,1.35,6.513,6.513,77.62,AHH,-1.839,0.0500837,0.00512144,1.04752 PSD95pdz3_R354S,PSD95pdz3_354,PSD95pdz3,PSD95pdz3,P31016,1.04753,NO,354,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.582,-3.067,1.485,6.21887,,,,,23.7791,,,,HBB,-1.44833,0.0758425,0.000650924,1.04753 kka2_1:4_S114G,kka2_1:4_114,Kka2,kka2_1:4,P00552,1.04755,NO,114,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.527,-2.602,0.075,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.168804,0.00705262,1.04755 beta-lactamase_0_R239A,beta-lactamase_0_239,TEM-1,beta-lactamase_0,P62593,1.04756,NO,239,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.0500837,0.00213852,1.04756 gb1_D262I,gb1_262,gb1,gb1,P06654,1.04757,NO,262,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-3.132,-3.72,0.588,,,,,,,1.304,,45.54,PAP,-2.05233,0.177985,0.00413102,1.04757 gb1_V255Q,gb1_255,gb1,gb1,P06654,1.04757,NO,255,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-3.127,-3.594,0.467,,,,,,,1.323,,45.54,BHH,-2.03867,0.177985,0.00408354,1.04757 kka2_1:8_S251G,kka2_1:8_251,Kka2,kka2_1:8,P00552,1.04757,NO,251,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.636,-2.736,0.1,,0.712,H,A,0.27,-0.25,,,71.59,APP,-2.09367,0.100394,0.0138916,1.04757 kka2_1:8_S251G,kka2_1:8_251,Kka2,kka2_1:8,P00552,1.04757,NO,251,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.636,-2.736,0.1,,0.712,H,A,0.27,-0.25,,,71.59,APP,-2.09367,0.100394,0.0138916,1.04757 PSD95pdz3_G335M,PSD95pdz3_335,PSD95pdz3,PSD95pdz3,P31016,1.04757,NO,335,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.008,-4.612,3.604,4.76223,,,,,22.4225,,,,AOH,-1.34733,0.0758425,0.000900493,1.04757 kka2_1:4_A137H,kka2_1:4_137,Kka2,kka2_1:4,P00552,1.04759,NO,137,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.156,-4.943,2.787,,0.029,H,A,0.46,0.34,2.227,,63.26,PHB,-2.559,0.168804,0.00515054,1.04759 beta-lactamase_0_E87K,beta-lactamase_0_87,TEM-1,beta-lactamase_0,P62593,1.0476,NO,87,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.421,-2.715,1.294,,0.048,,B,1.04,0.92,1.159,,64.69,PAP,-1.969,0.0500837,0.00337888,1.0476 beta-lactamase_0_G253C,beta-lactamase_0_253,TEM-1,beta-lactamase_0,P62593,1.0476,NO,253,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.0500837,0.00786358,1.0476 beta-lactamase_0_I244S,beta-lactamase_0_244,TEM-1,beta-lactamase_0,P62593,1.04762,NO,244,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.555,-3.602,2.047,,,E,B,0.48,-0.84,1.241,,77.62,OHH,-1.385,0.0500837,0.00605379,1.04762 beta-lactamase_0_G142L,beta-lactamase_0_142,TEM-1,beta-lactamase_0,P62593,1.04766,NO,142,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.707,-3.771,3.064,,0.034,,p,0.29,-0.64,1.947,,64.69,OOO,-0.834,0.0500837,0.00060149,1.04766 beta-lactamase_0_N152L,beta-lactamase_0_152,TEM-1,beta-lactamase_0,P62593,1.04767,NO,152,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-2.757,-3.55,0.793,,0.863,H,A,0.61,0.92,2.151,,77.62,BPH,-2.97,0.0500837,0.00471429,1.04767 kka2_1:4_P194D,kka2_1:4_194,Kka2,kka2_1:4,P00552,1.04767,NO,194,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.846,-2.601,1.755,,0.308,G,A,0.52,-1.19,0.213,,53.03,HOP,-0.888333,0.168804,0.00314194,1.04767 beta-lactamase_156_A211D,beta-lactamase_156_211,TEM-1,beta-lactamase_156,P62593,1.04775,NO,211,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.896,-1.934,0.038,,0.369,T,A,0.46,-0.69,8.527,8.527,77.62,AHA,-1.94633,0.111618,0.00648183,1.04775 beta-lactamase_0_T27A,beta-lactamase_0_27,TEM-1,beta-lactamase_0,P62593,1.04776,NO,27,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.905,-2.5,0.595,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.0500837,0.00306559,1.04776 beta-lactamase_0_G43M,beta-lactamase_0_43,TEM-1,beta-lactamase_0,P62593,1.04779,NO,43,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.62,-4.93,4.31,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.0500837,0.00120151,1.04779 kka2_1:4_A64Y,kka2_1:4_64,Kka2,kka2_1:4,P00552,1.04781,NO,64,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.496,-4.253,2.757,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.168804,0.00705578,1.04781 beta-lactamase_0_P25W,beta-lactamase_0_25,TEM-1,beta-lactamase_0,P62593,1.04783,NO,25,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.526,-5.419,3.893,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.0500837,0.00347571,1.04783 beta-lactamase_39_G154W,beta-lactamase_39_154,TEM-1,beta-lactamase_39,P62593,1.04787,NO,154,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.823,-5.233,4.41,,0.54,T,l,0.29,-0.56,1.151,,64.69,HOA,-1.635,0.0495842,0.00180205,1.04787 beta-lactamase_156_E61K,beta-lactamase_156_61,TEM-1,beta-lactamase_156,P62593,1.04792,NO,61,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.115,-3.46,1.345,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.111618,0.00440955,1.04792 PSD95pdz3_T321K,PSD95pdz3_321,PSD95pdz3,PSD95pdz3,P31016,1.04792,NO,321,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.391,-3.139,1.748,5.19953,,,,,20.3371,,,,PPO,-1.306,0.0758425,0.00106992,1.04792 beta-lactamase_0_Q204M,beta-lactamase_0_204,TEM-1,beta-lactamase_0,P62593,1.04793,NO,204,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-1.382,-4.445,3.063,,0.204,H,A,0.64,0.09,2.646,,66.08,PPH,-1.49067,0.0500837,0.00364106,1.04793 beta-lactamase_0_I258S,beta-lactamase_0_258,TEM-1,beta-lactamase_0,P62593,1.04795,NO,258,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.0500837,0.007931,1.04795 PSD95pdz3_I389H,PSD95pdz3_389,PSD95pdz3,PSD95pdz3,P31016,1.04802,NO,389,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.628,-4.682,3.054,5.15116,,,,,14.8038,1.498,,87.71,HHH,-1.52167,0.0758425,0.00148097,1.04802 beta-lactamase_0_E102R,beta-lactamase_0_102,TEM-1,beta-lactamase_0,P62593,1.04803,NO,102,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.118,-3.801,1.683,,0.722,S,B,1.04,1.82,4.773,,73.08,HAH,-1.581,0.0500837,0.00486633,1.04803 gb1_D262Q,gb1_262,gb1,gb1,P06654,1.04805,NO,262,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-3.132,-3.434,0.302,,,,,,,1.304,,45.54,PAP,-2.05233,0.177985,0.00413102,1.04805 beta-lactamase_P60D,beta-lactamase_60,TEM-1,beta-lactamase,P62593,1.04807,NO,60,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-2.469,-3.676,1.207,5.51353,0.256,T,A,0.73,-0.56,3.653,,77.62,BOA,-1.97633,0.221079,0.00521318,1.04807 beta-lactamase_V8Y,beta-lactamase_8,TEM-1,beta-lactamase,P62593,1.04811,NO,8,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-2.358,-4.031,1.673,,,,,,,0.575,,77.62,BHH,-2.06267,0.221079,0.00226401,1.04811 beta-lactamase_0_A77M,beta-lactamase_0_77,TEM-1,beta-lactamase_0,P62593,1.04813,NO,77,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.234,-4.524,3.29,,0.039,H,A,0.46,-0.56,2.591,,64.34,OHH,-1.294,0.0500837,0.00282362,1.04813 kka2_1:2_D156A,kka2_1:2_156,Kka2,kka2_1:2,P00552,1.04814,NO,156,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.696,-2.256,0.56,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.295029,0.00926998,1.04814 kka2_1:8_E182Q,kka2_1:8_182,Kka2,kka2_1:8,P00552,1.04814,NO,182,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.516,-2.606,1.09,,0.326,,B,1.52,0.75,2.568,,65.53,OAA,-1.806,0.100394,0.00641548,1.04814 kka2_1:8_E182Q,kka2_1:8_182,Kka2,kka2_1:8,P00552,1.04814,NO,182,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.516,-2.606,1.09,,0.326,,B,1.52,0.75,2.568,,65.53,OAA,-1.806,0.100394,0.00641548,1.04814 kka2_1:8_A108F,kka2_1:8_108,Kka2,kka2_1:8,P00552,1.04815,NO,108,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.061,-4.427,2.366,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.100394,0.00751209,1.04815 kka2_1:8_A108F,kka2_1:8_108,Kka2,kka2_1:8,P00552,1.04815,NO,108,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.061,-4.427,2.366,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.100394,0.00751209,1.04815 beta-lactamase_0_P217G,beta-lactamase_0_217,TEM-1,beta-lactamase_0,P62593,1.04816,NO,217,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-2.062,-2.748,0.686,,0.496,I,A,0.52,-0.33,1.087,,74.48,OOH,-1.64333,0.0500837,0.00463211,1.04816 kka2_1:8_W15R,kka2_1:8_15,Kka2,kka2_1:8,P00552,1.04818,NO,15,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-1.392,-4.195,2.803,,0.01,G,A,1.51,0.15,0.827,,52.27,HHH,-2.10533,0.100394,0.00585505,1.04818 kka2_1:8_W15R,kka2_1:8_15,Kka2,kka2_1:8,P00552,1.04818,NO,15,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-1.392,-4.195,2.803,,0.01,G,A,1.51,0.15,0.827,,52.27,HHH,-2.10533,0.100394,0.00585505,1.04818 beta-lactamase_0_E272F,beta-lactamase_0_272,TEM-1,beta-lactamase_0,P62593,1.04819,NO,272,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.0500837,0.00545371,1.04819 beta-lactamase_0_E175C,beta-lactamase_0_175,TEM-1,beta-lactamase_0,P62593,1.04824,NO,175,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.336,-5.076,2.74,,0.551,,A,1.04,1.05,2.334,,77.62,AAB,-1.31233,0.0500837,0.00482205,1.04824 beta-lactamase_39_Q86F,beta-lactamase_39_86,TEM-1,beta-lactamase_39,P62593,1.04826,NO,86,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.4,-4.354,1.954,,0.696,S,A,0.64,2.38,27.704,27.704,77.62,OPA,-1.61067,0.0495842,0.00450027,1.04826 PSD95pdz3_G322T,PSD95pdz3_322,PSD95pdz3,PSD95pdz3,P31016,1.04826,NO,322,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.008,-3.328,2.32,5.24791,,,,,16.3275,,,,POH,-1.24867,0.0758425,0.00105821,1.04826 beta-lactamase_0_F64A,beta-lactamase_0_64,TEM-1,beta-lactamase_0,P62593,1.04827,NO,64,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-0.841,-3.303,2.462,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.0500837,0.000947691,1.04827 beta-lactamase_39_P25C,beta-lactamase_39_25,TEM-1,beta-lactamase_39,P62593,1.04827,NO,25,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.526,-5.046,3.52,,0.624,H,A,0.52,0.14,1.157,,73.08,BOA,-2.15367,0.0495842,0.00347571,1.04827 PSD95pdz3_G364R,PSD95pdz3_364,PSD95pdz3,PSD95pdz3,P31016,1.04828,NO,364,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.008,-3.615,2.607,5.53299,,,,,21.28,,,,POH,-1.33667,0.0758425,0.00050942,1.04828 beta-lactamase_39_S221P,beta-lactamase_39_221,TEM-1,beta-lactamase_39,P62593,1.04829,NO,221,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.754,-3.814,2.06,,0.624,H,A,0.27,-0.2,2.69,,74.48,BPH,-1.59967,0.0495842,0.0046094,1.04829 PSD95pdz3_N363C,PSD95pdz3_363,PSD95pdz3,PSD95pdz3,P31016,1.04829,NO,363,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-1.41,-4.769,3.359,5.23349,,,,,20.7037,,,,HPO,-1.29433,0.0758425,0.000524014,1.04829 kka2_1:8_M178H,kka2_1:8_178,Kka2,kka2_1:8,P00552,1.0483,NO,178,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-3.206,-4.758,1.552,,0.554,,b,1.59,0.68,13.268,13.268,71.59,BHO,-2.154,0.100394,0.00717253,1.0483 kka2_1:8_M178H,kka2_1:8_178,Kka2,kka2_1:8,P00552,1.0483,NO,178,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-3.206,-4.758,1.552,,0.554,,b,1.59,0.68,13.268,13.268,71.59,BHO,-2.154,0.100394,0.00717253,1.0483 beta-lactamase_0_R159M,beta-lactamase_0_159,TEM-1,beta-lactamase_0,P62593,1.04831,NO,159,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-0.94,-4.529,3.589,,0.316,,B,1.2,-0.55,1.426,,64.34,PBH,-1.011,0.0500837,0.00108472,1.04831 beta-lactamase_39_A215H,beta-lactamase_39_215,TEM-1,beta-lactamase_39,P62593,1.04831,NO,215,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.503,-4.741,3.238,,,,a,0.46,-0.93,0.494,,74.48,HHO,-1.42633,0.0495842,0.00544007,1.04831 kka2_1:8_E86Y,kka2_1:8_86,Kka2,kka2_1:8,P00552,1.04831,NO,86,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.86,-2.948,1.088,,0.369,,B,1.52,1.92,,,63.26,PAH,-1.98067,0.100394,0.00642858,1.04831 kka2_1:8_E86Y,kka2_1:8_86,Kka2,kka2_1:8,P00552,1.04831,NO,86,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.86,-2.948,1.088,,0.369,,B,1.52,1.92,,,63.26,PAH,-1.98067,0.100394,0.00642858,1.04831 PSD95pdz3_S350G,PSD95pdz3_350,PSD95pdz3,PSD95pdz3,P31016,1.04831,NO,350,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.519,-2.59,1.071,4.97629,,,,,25.01,,,,HPO,-1.29133,0.0758425,0.000704883,1.04831 kka2_1:1_G234T,kka2_1:1_234,Kka2,kka2_1:1,P00552,1.04832,NO,234,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-2.9,-3.606,0.706,,0.494,H,A,0.29,-0.29,1.753,,71.59,OOA,-1.86767,0.520039,0.00984449,1.04832 PSD95pdz3_S350E,PSD95pdz3_350,PSD95pdz3,PSD95pdz3,P31016,1.04836,NO,350,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.519,-2.897,1.378,4.97629,,,,,25.01,,,,HPO,-1.29133,0.0758425,0.000704883,1.04836 PSD95pdz3_G364E,PSD95pdz3_364,PSD95pdz3,PSD95pdz3,P31016,1.04844,NO,364,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.008,-3.347,2.339,5.53299,,,,,21.28,,,,POH,-1.33667,0.0758425,0.00050942,1.04844 beta-lactamase_625_I277F,beta-lactamase_625_277,TEM-1,beta-lactamase_625,P62593,1.04846,NO,277,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.213352,0.0169305,1.04846 WW_domain_V171Y,WW_domain_171,Yap65,WW_domain,P46937,1.04847,NO,171,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.547,-3.903,2.356,,,,,,,3.459,,70.24,AHO,-1.265,0.153962,0.00184125,1.04847 beta-lactamase_0_F228P,beta-lactamase_0_228,TEM-1,beta-lactamase_0,P62593,1.04862,NO,228,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-2.342,-3.088,0.746,,0.154,E,B,0.58,-0.42,15.504,15.504,63.29,HHH,-1.53033,0.0500837,0.0046669,1.04862 E1_Ubiquitin_F45N,E1_Ubiquitin_45,Uba1,E1_Ubiquitin,P0CG63,1.04863,NO,45,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.149,-3.94,2.791,,0.26,E,B,,-0.99,,,,HHH,-1.316,0.18783,0.00193245,1.04863 WW_domain_D194L,WW_domain_194,Yap65,WW_domain,P46937,1.04863,NO,194,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.536,-3.295,1.759,5.95614,,,,,,1.948,,74.4,HAP,-1.78933,0.153962,0.00483742,1.04863 beta-lactamase_F13M,beta-lactamase_13,TEM-1,beta-lactamase,P62593,1.0487,NO,13,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-2.394,-4.13,1.736,,,,,,,4.079,,77.62,OHH,-2.382,0.221079,0.0029078,1.0487 beta-lactamase_Q97Y,beta-lactamase_97,TEM-1,beta-lactamase,P62593,1.0487,NO,97,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.072,-4.35,2.278,6.30204,0.823,G,A,1.1,2.42,1.157,,77.62,PPP,-2.43833,0.221079,0.0045116,1.0487 beta-lactamase_0_E56G,beta-lactamase_0_56,TEM-1,beta-lactamase_0,P62593,1.04871,NO,56,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.043,-2.304,0.261,,0.198,E,B,1.04,0.31,1.491,,72.73,HAP,-1.94033,0.0500837,0.00238534,1.04871 kka2_1:4_E17C,kka2_1:4_17,Kka2,kka2_1:4,P00552,1.04874,NO,17,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.154,-5.239,3.085,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.168804,0.00688738,1.04874 PSD95pdz3_R313H,PSD95pdz3_313,PSD95pdz3,PSD95pdz3,P31016,1.04874,NO,313,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.582,-3.912,2.33,6.63563,,,,,18.3955,,,,BBH,-1.59733,0.0758425,0.000840067,1.04874 WW_domain_V171I,WW_domain_171,Yap65,WW_domain,P46937,1.04875,NO,171,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.547,-2.825,1.278,,,,,,,3.459,,70.24,AHO,-1.265,0.153962,0.00184125,1.04875 beta-lactamase_39_V214W,beta-lactamase_39_214,TEM-1,beta-lactamase_39,P62593,1.04878,NO,214,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.299,-5.33,4.031,,0.375,S,A,0.44,-0.44,18.838,18.838,74.48,BHH,-1.53733,0.0495842,0.00628442,1.04878 kka2_1:8_D183R,kka2_1:8_183,Kka2,kka2_1:8,P00552,1.04879,NO,183,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.204,-2.951,1.747,,0.518,.,b,0.75,0.25,0.347,,52.27,AAH,-1.40533,0.100394,0.00426304,1.04879 kka2_1:8_D183R,kka2_1:8_183,Kka2,kka2_1:8,P00552,1.04879,NO,183,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.204,-2.951,1.747,,0.518,.,b,0.75,0.25,0.347,,52.27,AAH,-1.40533,0.100394,0.00426304,1.04879 WW_domain_S183W,WW_domain_183,Yap65,WW_domain,P46937,1.04879,NO,183,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.95,-5.328,3.378,5.35576,,,,,,1.594,,83.93,PPP,-1.48733,0.153962,0.00445513,1.04879 kka2_1:1_I2H,kka2_1:1_2,Kka2,kka2_1:1,P00552,1.0488,NO,2,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.787,-4.676,2.889,,,,,,,2.329,,71.59,HHA,-1.92433,0.520039,0.00246644,1.0488 kka2_1:2_A150L,kka2_1:2_150,Kka2,kka2_1:2,P00552,1.04884,NO,150,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.949,-3.346,2.397,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.295029,0.0045009,1.04884 kka2_1:4_G55F,kka2_1:4_55,Kka2,kka2_1:4,P00552,1.04886,NO,55,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.625,-3.32,1.695,,0.517,S,b,0.75,1.19,15.753,15.753,63.64,POH,-2.05967,0.168804,0.00667877,1.04886 beta-lactamase_39_P217I,beta-lactamase_39_217,TEM-1,beta-lactamase_39,P62593,1.04891,NO,217,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-2.062,-4.071,2.009,,0.496,I,A,0.52,-0.33,21.172,21.172,74.48,OOH,-1.64333,0.0495842,0.00463211,1.04891 beta-lactamase_39_G194K,beta-lactamase_39_194,TEM-1,beta-lactamase_39,P62593,1.04892,NO,194,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.396,-3.557,2.161,,0.276,S,b,0.29,0.36,4.852,,67.83,POA,-1.832,0.0495842,0.00392163,1.04892 beta-lactamase_0_L218M,beta-lactamase_0_218,TEM-1,beta-lactamase_0,P62593,1.04895,NO,218,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.391,-4.267,2.876,,,I,b,0.55,-0.53,28.707,28.707,74.48,OHH,-1.58867,0.0500837,0.00618274,1.04895 Pab1_G163L,Pab1_163,Pab1,Pab1,P04147,1.04896,NO,163,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.809,-3.625,2.816,,0.356,B,g,,0.55,,,,POB,-1.80667,0.175299,0.00030953,1.04896 beta-lactamase_39_I93P,beta-lactamase_39_93,TEM-1,beta-lactamase_39,P62593,1.04907,NO,93,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.401,-2.926,1.525,,0.128,E,B,0.48,0.44,1.757,,67.83,BHB,-1.873,0.0495842,0.00527066,1.04907 kka2_1:8_D118V,kka2_1:8_118,Kka2,kka2_1:8,P00552,1.0491,NO,118,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.07,-3.108,1.038,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.100394,0.0067852,1.0491 kka2_1:8_D118V,kka2_1:8_118,Kka2,kka2_1:8,P00552,1.0491,NO,118,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.07,-3.108,1.038,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.100394,0.0067852,1.0491 kka2_1:4_K138T,kka2_1:4_138,Kka2,kka2_1:4,P00552,1.04916,NO,138,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-2.5,-2.841,0.341,,0.594,H,A,1.3,0.98,21.267,21.267,71.59,HBB,-2.48833,0.168804,0.00628542,1.04916 kka2_1:2_A150Q,kka2_1:2_150,Kka2,kka2_1:2,P00552,1.04918,NO,150,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.949,-2.897,1.948,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.295029,0.0045009,1.04918 PSD95pdz3_R313Y,PSD95pdz3_313,PSD95pdz3,PSD95pdz3,P31016,1.04918,NO,313,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.582,-3.844,2.262,6.63563,,,,,18.3955,,,,BBH,-1.59733,0.0758425,0.000840067,1.04918 beta-lactamase_39_I285H,beta-lactamase_39_285,TEM-1,beta-lactamase_39,P62593,1.04924,NO,285,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.845,-3.788,1.943,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.0495842,0.101555,1.04924 gb1_V247F,gb1_247,gb1,gb1,P06654,1.04924,NO,247,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.711,-3.72,2.009,,,,,,,0.805,,44.87,HHA,-1.485,0.177985,0.00435373,1.04924 kka2_1:8_P45V,kka2_1:8_45,Kka2,kka2_1:8,P00552,1.04926,NO,45,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.774,-3.689,1.915,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.100394,0.00590481,1.04926 kka2_1:8_P45V,kka2_1:8_45,Kka2,kka2_1:8,P00552,1.04926,NO,45,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.774,-3.689,1.915,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.100394,0.00590481,1.04926 beta-lactamase_0_Q86E,beta-lactamase_0_86,TEM-1,beta-lactamase_0,P62593,1.04927,NO,86,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.4,-2.379,-0.021,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.0500837,0.00450027,1.04927 kka2_1:8_Q27P,kka2_1:8_27,Kka2,kka2_1:8,P00552,1.04927,NO,27,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-1.659,-3,1.341,,0.608,.,A,0.64,0.71,3.919,,65.53,PPP,-1.90733,0.100394,0.00595365,1.04927 kka2_1:8_Q27P,kka2_1:8_27,Kka2,kka2_1:8,P00552,1.04927,NO,27,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-1.659,-3,1.341,,0.608,.,A,0.64,0.71,3.919,,65.53,PPP,-1.90733,0.100394,0.00595365,1.04927 beta-lactamase_0_S266A,beta-lactamase_0_266,TEM-1,beta-lactamase_0,P62593,1.04934,NO,266,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.369,-2.686,1.317,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.0500837,0.0140785,1.04934 beta-lactamase_39_F149L,beta-lactamase_39_149,TEM-1,beta-lactamase_39,P62593,1.04936,NO,149,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.299,-3.137,1.838,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.0495842,0.00418462,1.04936 beta-lactamase_39_S201Q,beta-lactamase_39_201,TEM-1,beta-lactamase_39,P62593,1.04937,NO,201,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.183,-2.836,1.653,,0.064,H,A,0.27,-0.07,3.54,,64.69,HPB,-1.451,0.0495842,0.00198815,1.04937 beta-lactamase_39_I244C,beta-lactamase_39_244,TEM-1,beta-lactamase_39,P62593,1.04943,NO,244,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.555,-4.712,3.157,,,E,B,0.48,-0.84,1.325,,77.62,OHH,-1.385,0.0495842,0.00605379,1.04943 kka2_1:4_D118K,kka2_1:4_118,Kka2,kka2_1:4,P00552,1.04944,NO,118,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.07,-2.906,0.836,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.168804,0.0067852,1.04944 beta-lactamase_0_P105T,beta-lactamase_0_105,TEM-1,beta-lactamase_0,P62593,1.04945,NO,105,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-0.813,-3.385,2.572,,0.226,T,A,0.52,0.8,3.48,,63.29,POH,-1.01533,0.0500837,0.0011981,1.04945 kka2_1:2_S105C,kka2_1:2_105,Kka2,kka2_1:2,P00552,1.04949,NO,105,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.945,-3.198,1.253,,0.056,S,B,0.27,-1.04,3.442,,65.53,PPB,-2.17033,0.295029,0.00847233,1.04949 beta-lactamase_156_L223M,beta-lactamase_156_223,TEM-1,beta-lactamase_156,P62593,1.04957,NO,223,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.055,-3.986,2.931,,0.27,,B,0.55,0.09,1.511,,74.48,HHO,-1.35033,0.111618,0.00372793,1.04957 PSD95pdz3_G344F,PSD95pdz3_344,PSD95pdz3,PSD95pdz3,P31016,1.04957,NO,344,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.008,-3.974,2.966,4.83855,,,,,14.06,,,,HOO,-1.10767,0.0758425,0.00078498,1.04957 beta-lactamase_156_S283N,beta-lactamase_156_283,TEM-1,beta-lactamase_156,P62593,1.04963,NO,283,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.111618,0.0429138,1.04963 beta-lactamase_0_I206S,beta-lactamase_0_206,TEM-1,beta-lactamase_0,P62593,1.04965,NO,206,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-2.429,-3.468,1.039,,0.173,H,A,0.48,-0.34,3.411,,77.62,HHA,-1.805,0.0500837,0.00528934,1.04965 kka2_1:8_L94M,kka2_1:8_94,Kka2,kka2_1:8,P00552,1.04967,NO,94,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.618,-1.512,-0.106,,0.058,E,B,1.59,-0.52,2.197,,56.06,HHO,-1.612,0.100394,0.00520888,1.04967 kka2_1:8_L94M,kka2_1:8_94,Kka2,kka2_1:8,P00552,1.04967,NO,94,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.618,-1.512,-0.106,,0.058,E,B,1.59,-0.52,2.197,,56.06,HHO,-1.612,0.100394,0.00520888,1.04967 beta-lactamase_0_R202A,beta-lactamase_0_202,TEM-1,beta-lactamase_0,P62593,1.04968,NO,202,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.292,-2.462,1.17,,0.188,H,A,1.2,0.62,7.016,,77.62,PBP,-1.54767,0.0500837,0.00321899,1.04968 beta-lactamase_39_E26I,beta-lactamase_39_26,TEM-1,beta-lactamase_39,P62593,1.04968,NO,26,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.454,-3.782,1.328,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.0495842,0.00297948,1.04968 gb1_A274H,gb1_274,gb1,gb1,P06654,1.04971,NO,274,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.728,-4.302,2.574,,,,,,,4.162,4.162,11.83,AHP,-1.81767,0.177985,0.0068419,1.04971 gb1_V247Y,gb1_247,gb1,gb1,P06654,1.04971,NO,247,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.711,-3.882,2.171,,,,,,,0.805,,44.87,HHA,-1.485,0.177985,0.00435373,1.04971 kka2_1:2_G55Q,kka2_1:2_55,Kka2,kka2_1:2,P00552,1.04975,NO,55,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.625,-4.083,2.458,,0.517,S,b,0.75,1.19,15.753,15.753,63.64,POH,-2.05967,0.295029,0.00667877,1.04975 beta-lactamase_39_G141L,beta-lactamase_39_141,TEM-1,beta-lactamase_39,P62593,1.04977,NO,141,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.828,-3.844,3.016,,0.575,T,l,0.29,-0.28,0.722,,64.69,HOO,-1.08933,0.0495842,0.0012419,1.04977 kka2_1:8_R202N,kka2_1:8_202,Kka2,kka2_1:8,P00552,1.04979,NO,202,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.761,-3.087,1.326,,0.607,E,B,1.2,0.48,1.409,,52.27,OBH,-1.41067,0.100394,0.00696498,1.04979 kka2_1:8_R202N,kka2_1:8_202,Kka2,kka2_1:8,P00552,1.04979,NO,202,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.761,-3.087,1.326,,0.607,E,B,1.2,0.48,1.409,,52.27,OBH,-1.41067,0.100394,0.00696498,1.04979 PSD95pdz3_G364F,PSD95pdz3_364,PSD95pdz3,PSD95pdz3,P31016,1.04979,NO,364,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.008,-3.974,2.966,5.53299,,,,,21.28,,,,POH,-1.33667,0.0758425,0.00050942,1.04979 beta-lactamase_0_I93Q,beta-lactamase_0_93,TEM-1,beta-lactamase_0,P62593,1.04983,NO,93,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.401,-4.315,2.914,,0.128,E,B,0.48,0.44,1.266,,67.83,BHB,-1.873,0.0500837,0.00527066,1.04983 beta-lactamase_0_R41A,beta-lactamase_0_41,TEM-1,beta-lactamase_0,P62593,1.04985,NO,41,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-0.942,-3.041,2.099,,0.321,E,B,1.2,-0.07,2.68,,65.03,HBH,-1.30267,0.0500837,0.00123327,1.04985 kka2_1:8_G234C,kka2_1:8_234,Kka2,kka2_1:8,P00552,1.04985,NO,234,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-2.9,-5.225,2.325,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.100394,0.00984449,1.04985 kka2_1:8_G234C,kka2_1:8_234,Kka2,kka2_1:8,P00552,1.04985,NO,234,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-2.9,-5.225,2.325,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.100394,0.00984449,1.04985 kka2_1:4_P249R,kka2_1:4_249,Kka2,kka2_1:4,P00552,1.04986,NO,249,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.867,-3.291,1.424,,0.406,.,B,0.52,-0.01,,,92.05,HOA,-1.66867,0.168804,0.011045,1.04986 PSD95pdz3_R354G,PSD95pdz3_354,PSD95pdz3,PSD95pdz3,P31016,1.04986,NO,354,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.582,-3.04,1.458,6.21887,,,,,23.7791,,,,HBB,-1.44833,0.0758425,0.000650924,1.04986 beta-lactamase_0_S256M,beta-lactamase_0_256,TEM-1,beta-lactamase_0,P62593,1.04987,NO,256,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.0500837,0.00710634,1.04987 kka2_1:1_A137M,kka2_1:1_137,Kka2,kka2_1:1,P00552,1.04993,NO,137,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.156,-4.232,2.076,,0.029,H,A,0.46,0.34,1.323,,63.26,PHB,-2.559,0.520039,0.00515054,1.04993 PSD95pdz3_T387H,PSD95pdz3_387,PSD95pdz3,PSD95pdz3,P31016,1.04997,NO,387,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.391,-4.362,2.971,5.20757,,,,,18.8043,,,,HPH,-1.49533,0.0758425,0.000167911,1.04997 beta-lactamase_39_N274M,beta-lactamase_39_274,TEM-1,beta-lactamase_39,P62593,1.05,NO,274,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.0495842,0.0110418,1.05 beta-lactamase_39_V157Y,beta-lactamase_39_157,TEM-1,beta-lactamase_39,P62593,1.05,NO,157,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.751,-2.838,1.087,,0.308,S,a,0.44,-0.75,10.364,10.364,69.58,BHP,-2.00767,0.0495842,0.00506849,1.05 kka2_1:4_L243T,kka2_1:4_243,Kka2,kka2_1:4,P00552,1.05001,NO,243,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-2.651,-2.872,0.221,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.168804,0.00884927,1.05001 beta-lactamase_156_V29M,beta-lactamase_156_29,TEM-1,beta-lactamase_156,P62593,1.05002,NO,29,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-2.856,-4.721,1.865,,0.733,H,A,0.44,-0.78,3.685,,93.01,HHB,-2.24733,0.111618,0.00318969,1.05002 beta-lactamase_625_T138N,beta-lactamase_625_138,TEM-1,beta-lactamase_625,P62593,1.05004,NO,138,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.506,-2.961,0.455,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.213352,0.00487868,1.05004 kka2_1:4_A65C,kka2_1:4_65,Kka2,kka2_1:4,P00552,1.05004,NO,65,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.744,-5.062,3.318,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.168804,0.00709258,1.05004 kka2_1:2_L152K,kka2_1:2_152,Kka2,kka2_1:2,P00552,1.05005,NO,152,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.521,-3.615,2.094,,0.547,.,A,0.55,1.36,4.526,,63.64,OHH,-1.162,0.295029,0.00674868,1.05005 beta-lactamase_0_Y44V,beta-lactamase_0_44,TEM-1,beta-lactamase_0,P62593,1.05007,NO,44,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-2.547,-1.805,-0.742,,,E,B,0.21,-0.45,1.751,,73.78,OHH,-1.86267,0.0500837,0.00426364,1.05007 gb1_D272R,gb1_272,gb1,gb1,P06654,1.05007,NO,272,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.457,-3.548,2.091,,,,,,,0.234,,11.83,HAA,-1.54533,0.177985,0.00218257,1.05007 kka2_1:1_D5N,kka2_1:1_5,Kka2,kka2_1:1,P00552,1.05008,NO,5,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.306,-3.103,1.797,,,,,,,0.895,,71.59,PAO,-1.784,0.520039,0.00222864,1.05008 kka2_1:2_D5F,kka2_1:2_5,Kka2,kka2_1:2,P00552,1.05014,NO,5,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.306,-4.103,2.797,,,,,,,,,71.59,PAO,-1.784,0.295029,0.00222864,1.05014 PSD95pdz3_G351S,PSD95pdz3_351,PSD95pdz3,PSD95pdz3,P31016,1.05014,NO,351,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.008,-2.842,1.834,5.44798,,,,,20.7625,,,,POA,-1.37133,0.0758425,0.000691282,1.05014 beta-lactamase_625_K190E,beta-lactamase_625_190,TEM-1,beta-lactamase_625,P62593,1.05015,NO,190,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.994,-3.44,1.446,,0.371,H,A,2.34,0.16,29.753,29.753,77.62,BBH,-1.64167,0.213352,0.00574527,1.05015 beta-lactamase_39_L248I,beta-lactamase_39_248,TEM-1,beta-lactamase_39,P62593,1.05026,NO,248,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.0495842,0.00428493,1.05026 kka2_1:4_C31G,kka2_1:4_31,Kka2,kka2_1:4,P00552,1.05026,NO,31,C,G,CG,Special,Special,5.07,3.29388,-1.77612,159,121,75,-46,108.5,60.1,-48.4,-2.246,-3.573,1.327,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.168804,0.00681582,1.05026 kka2_1:4_L93M,kka2_1:4_93,Kka2,kka2_1:4,P00552,1.05027,NO,93,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.815,-3.907,3.092,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.168804,0.00131498,1.05027 kka2_1:4_A108E,kka2_1:4_108,Kka2,kka2_1:4,P00552,1.05028,NO,108,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.061,-2.517,0.456,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.168804,0.00751209,1.05028 beta-lactamase_39_I285K,beta-lactamase_39_285,TEM-1,beta-lactamase_39,P62593,1.0503,NO,285,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.0495842,0.101555,1.0503 kka2_1:2_E231T,kka2_1:2_231,Kka2,kka2_1:2,P00552,1.05033,NO,231,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.002,-3.44,1.438,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.295029,0.00732383,1.05033 kka2_1:2_G151S,kka2_1:2_151,Kka2,kka2_1:2,P00552,1.05037,NO,151,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.873,-2.614,1.741,,0.678,T,l,0.29,1.36,1.357,,49.62,HOH,-1.11433,0.295029,0.00339918,1.05037 beta-lactamase_0_C121P,beta-lactamase_0_121,TEM-1,beta-lactamase_0,P62593,1.05038,NO,121,C,P,CP,Special,Special,5.07,6.3,1.23,169,121,115,-6,108.5,112.7,4.2,-0.953,-4.102,3.149,,,H,A,0.46,-0.81,3.302,,63.29,HOP,-1.46767,0.0500837,0.000744322,1.05038 E1_Ubiquitin_T68F,E1_Ubiquitin_68,Uba1,E1_Ubiquitin,P0CG63,1.0504,NO,68,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,,,,,,,,,,,,,OPH,-1.039,0.18783,0.00314321,1.0504 kka2_1:4_G181V,kka2_1:4_181,Kka2,kka2_1:4,P00552,1.05044,NO,181,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-2.698,-2.527,-0.171,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.168804,0.00728319,1.05044 kka2_1:8_T85M,kka2_1:8_85,Kka2,kka2_1:8,P00552,1.05049,NO,85,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.165,-4.675,2.51,,0.576,E,B,0.22,1.39,22.154,22.154,71.59,HPA,-2.10133,0.100394,0.00634493,1.05049 kka2_1:8_T85M,kka2_1:8_85,Kka2,kka2_1:8,P00552,1.05049,NO,85,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.165,-4.675,2.51,,0.576,E,B,0.22,1.39,22.154,22.154,71.59,HPA,-2.10133,0.100394,0.00634493,1.05049 beta-lactamase_0_D99M,beta-lactamase_0_99,TEM-1,beta-lactamase_0,P62593,1.05051,NO,99,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.191,-3.198,2.007,,0.402,G,A,0.75,0.36,0.374,,64.69,PAH,-1.794,0.0500837,0.00305446,1.05051 kka2_1:8_E17C,kka2_1:8_17,Kka2,kka2_1:8,P00552,1.05053,NO,17,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.154,-5.239,3.085,,0.957,T,A,1.04,0.22,31.483,31.483,63.64,HAB,-2.432,0.100394,0.00688738,1.05053 kka2_1:8_E17C,kka2_1:8_17,Kka2,kka2_1:8,P00552,1.05053,NO,17,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.154,-5.239,3.085,,0.957,T,A,1.04,0.22,31.483,31.483,63.64,HAB,-2.432,0.100394,0.00688738,1.05053 kka2_1:8_L57M,kka2_1:8_57,Kka2,kka2_1:8,P00552,1.05053,NO,57,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.898,-4.404,2.506,,0.343,T,A,0.55,0.98,13.359,13.359,52.65,HHP,-2.20733,0.100394,0.00723769,1.05053 kka2_1:8_L57M,kka2_1:8_57,Kka2,kka2_1:8,P00552,1.05053,NO,57,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.898,-4.404,2.506,,0.343,T,A,0.55,0.98,13.359,13.359,52.65,HHP,-2.20733,0.100394,0.00723769,1.05053 kka2_1:1_D5R,kka2_1:1_5,Kka2,kka2_1:1,P00552,1.05055,NO,5,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.306,-3.57,2.264,,,,,,,0.895,,71.59,PAO,-1.784,0.520039,0.00222864,1.05055 beta-lactamase_39_I285M,beta-lactamase_39_285,TEM-1,beta-lactamase_39,P62593,1.05056,NO,285,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.0495842,0.101555,1.05056 kka2_1:8_Y244T,kka2_1:8_244,Kka2,kka2_1:8,P00552,1.05057,NO,244,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-0.775,-3.675,2.9,,0.066,H,A,1.25,-0.64,,,,HHO,-1.41267,0.100394,0.00453187,1.05057 kka2_1:8_Y244T,kka2_1:8_244,Kka2,kka2_1:8,P00552,1.05057,NO,244,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-0.775,-3.675,2.9,,0.066,H,A,1.25,-0.64,,,,HHO,-1.41267,0.100394,0.00453187,1.05057 beta-lactamase_0_T147W,beta-lactamase_0_147,TEM-1,beta-lactamase_0,P62593,1.05058,NO,147,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.149,-5.268,4.119,,0.281,H,A,0.22,-0.68,3.487,,64.34,HPH,-1.456,0.0500837,0.00226017,1.05058 kka2_1:4_P167K,kka2_1:4_167,Kka2,kka2_1:4,P00552,1.05061,NO,167,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-2.403,-3.717,1.314,,0.18,H,A,0.52,0.75,3.6,,64.39,HOH,-2.26633,0.168804,0.00543203,1.05061 kka2_1:8_A168W,kka2_1:8_168,Kka2,kka2_1:8,P00552,1.05065,NO,168,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.989,-5.548,3.559,,0.67,H,A,0.46,0.15,11.329,11.329,64.39,OHA,-2.12933,0.100394,0.00806773,1.05065 kka2_1:8_A168W,kka2_1:8_168,Kka2,kka2_1:8,P00552,1.05065,NO,168,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.989,-5.548,3.559,,0.67,H,A,0.46,0.15,11.329,11.329,64.39,OHA,-2.12933,0.100394,0.00806773,1.05065 beta-lactamase_39_T138I,beta-lactamase_39_138,TEM-1,beta-lactamase_39,P62593,1.05066,NO,138,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.506,-4.099,1.593,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.0495842,0.00487868,1.05066 kka2_1:8_G99S,kka2_1:8_99,Kka2,kka2_1:8,P00552,1.0507,NO,99,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.596,-3.189,2.593,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.100394,0.00186055,1.0507 kka2_1:8_G99S,kka2_1:8_99,Kka2,kka2_1:8,P00552,1.0507,NO,99,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.596,-3.189,2.593,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.100394,0.00186055,1.0507 PSD95pdz3_Q384W,PSD95pdz3_384,PSD95pdz3,PSD95pdz3,P31016,1.0507,NO,384,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-1.699,-4.779,3.08,5.49339,,,,,23.54,,,,OPP,-1.41333,0.0758425,0.000216736,1.0507 beta-lactamase_V29W,beta-lactamase_29,TEM-1,beta-lactamase,P62593,1.05074,NO,29,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-2.856,-5.465,2.609,5.58481,0.733,H,A,0.23,-0.78,1.287,,93.01,HHB,-2.24733,0.221079,0.00318969,1.05074 gb1_A274I,gb1_274,gb1,gb1,P06654,1.05077,NO,274,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.728,-3.683,1.955,,,,,,,4.162,4.162,11.83,AHP,-1.81767,0.177985,0.0068419,1.05077 beta-lactamase_0_V260N,beta-lactamase_0_260,TEM-1,beta-lactamase_0,P62593,1.05078,NO,260,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.0500837,0.00471757,1.05078 beta-lactamase_39_L219M,beta-lactamase_39_219,TEM-1,beta-lactamase_39,P62593,1.0508,NO,219,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.313,-3.006,1.693,,,I,A,0.55,-0.51,19.842,19.842,74.48,HHB,-1.21533,0.0495842,0.00664345,1.0508 PSD95pdz3_S350N,PSD95pdz3_350,PSD95pdz3,PSD95pdz3,P31016,1.0508,NO,350,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.519,-2.905,1.386,4.97629,,,,,25.01,,,,HPO,-1.29133,0.0758425,0.000704883,1.0508 PSD95pdz3_G319W,PSD95pdz3_319,PSD95pdz3,PSD95pdz3,P31016,1.05081,NO,319,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.008,-4.779,3.771,4.95387,,,,,18.8725,,,,BOP,-1.36967,0.0758425,0.00109317,1.05081 beta-lactamase_0_Q86T,beta-lactamase_0_86,TEM-1,beta-lactamase_0,P62593,1.05082,NO,86,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.4,-2.587,0.187,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.0500837,0.00450027,1.05082 PSD95pdz3_L342F,PSD95pdz3_342,PSD95pdz3,PSD95pdz3,P31016,1.05087,NO,342,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.347,-3.299,1.952,5.03015,,,,,12.0762,,,,HHH,-1.428,0.0758425,0.00081112,1.05087 kka2_1:8_T51M,kka2_1:8_51,Kka2,kka2_1:8,P00552,1.05088,NO,51,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.199,-4.634,2.435,,0.05,E,B,0.82,-0.05,5.399,,63.64,BPA,-1.76767,0.100394,0.00628861,1.05088 kka2_1:8_T51M,kka2_1:8_51,Kka2,kka2_1:8,P00552,1.05088,NO,51,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.199,-4.634,2.435,,0.05,E,B,0.82,-0.05,5.399,,63.64,BPA,-1.76767,0.100394,0.00628861,1.05088 gb1_E241Q,gb1_241,gb1,gb1,P06654,1.05089,NO,241,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.672,-3.317,1.645,,,,,,,0.344,,11.83,OAP,-1.27933,0.177985,0.00250604,1.05089 gb1_Q258R,gb1_258,gb1,gb1,P06654,1.05089,NO,258,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.095,-3.43,1.335,,,,,,,0.86,,37.28,BPH,-1.88333,0.177985,0.00437595,1.05089 beta-lactamase_0_E145Q,beta-lactamase_0_145,TEM-1,beta-lactamase_0,P62593,1.05091,NO,145,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.357,-2.979,0.622,,0.545,H,A,1.04,0.79,1.199,,77.62,BAH,-2.069,0.0500837,0.00553285,1.05091 kka2_1:4_A229E,kka2_1:4_229,Kka2,kka2_1:4,P00552,1.05091,NO,229,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.739,-2.079,0.34,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.168804,0.00942138,1.05091 beta-lactamase_0_T131E,beta-lactamase_0_131,TEM-1,beta-lactamase_0,P62593,1.05092,NO,131,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.328,-3.523,2.195,,,H,A,0.22,-0.69,3.306,,67.48,PPH,-1.00867,0.0500837,0.00345886,1.05092 beta-lactamase_0_T264H,beta-lactamase_0_264,TEM-1,beta-lactamase_0,P62593,1.05095,NO,264,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.0500837,0.0119399,1.05095 kka2_1:8_G151A,kka2_1:8_151,Kka2,kka2_1:8,P00552,1.05095,NO,151,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.873,-3.018,2.145,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.100394,0.00339918,1.05095 kka2_1:8_G151A,kka2_1:8_151,Kka2,kka2_1:8,P00552,1.05095,NO,151,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.873,-3.018,2.145,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.100394,0.00339918,1.05095 beta-lactamase_0_G281T,beta-lactamase_0_281,TEM-1,beta-lactamase_0,P62593,1.05098,NO,281,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.0500837,0.0406482,1.05098 kka2_1:2_A56G,kka2_1:2_56,Kka2,kka2_1:2,P00552,1.05098,NO,56,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.083,-2.527,0.444,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.295029,0.00717715,1.05098 beta-lactamase_625_T138K,beta-lactamase_625_138,TEM-1,beta-lactamase_625,P62593,1.05099,NO,138,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.506,-2.186,-0.32,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.213352,0.00487868,1.05099 beta-lactamase_39_S221I,beta-lactamase_39_221,TEM-1,beta-lactamase_39,P62593,1.051,NO,221,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.754,-3.812,2.058,,0.624,H,A,0.27,-0.2,2.69,,74.48,BPH,-1.59967,0.0495842,0.0046094,1.051 kka2_1:8_D156A,kka2_1:8_156,Kka2,kka2_1:8,P00552,1.05101,NO,156,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.696,-2.256,0.56,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.100394,0.00926998,1.05101 kka2_1:8_D156A,kka2_1:8_156,Kka2,kka2_1:8,P00552,1.05101,NO,156,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.696,-2.256,0.56,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.100394,0.00926998,1.05101 kka2_1:8_L152E,kka2_1:8_152,Kka2,kka2_1:8,P00552,1.05103,NO,152,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.521,-3.005,1.484,,0.547,.,A,0.55,1.36,1.442,,63.64,OHH,-1.162,0.100394,0.00674868,1.05103 kka2_1:8_L152E,kka2_1:8_152,Kka2,kka2_1:8,P00552,1.05103,NO,152,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.521,-3.005,1.484,,0.547,.,A,0.55,1.36,1.442,,63.64,OHH,-1.162,0.100394,0.00674868,1.05103 beta-lactamase_0_G194E,beta-lactamase_0_194,TEM-1,beta-lactamase_0,P62593,1.05105,NO,194,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.396,-2.361,0.965,,0.276,S,b,0.29,0.36,3.017,,67.83,POA,-1.832,0.0500837,0.00392163,1.05105 beta-lactamase_39_W208E,beta-lactamase_39_208,TEM-1,beta-lactamase_39,P62593,1.05105,NO,208,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-0.818,-3.89,3.072,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.0495842,0.00126609,1.05105 PSD95pdz3_E334K,PSD95pdz3_334,PSD95pdz3,PSD95pdz3,P31016,1.05109,NO,334,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.404,-2.689,1.285,5.60175,,,,,53.09,,,,OAO,-1.14,0.0758425,0.000912998,1.05109 gb1_D272N,gb1_272,gb1,gb1,P06654,1.05113,NO,272,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.457,-2.082,0.625,,,,,,,0.234,,11.83,HAA,-1.54533,0.177985,0.00218257,1.05113 gb1_Q228L,gb1_228,gb1,gb1,P06654,1.05113,NO,228,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,,,,,,,,,,,,,OPH,-1.282,0.177985,0.00391043,1.05113 PSD95pdz3_G333T,PSD95pdz3_333,PSD95pdz3,PSD95pdz3,P31016,1.05115,NO,333,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.008,-3.328,2.32,5.09445,,,,,48.755,,,,AOA,-1.22533,0.0758425,0.00092544,1.05115 beta-lactamase_0_D155W,beta-lactamase_0_155,TEM-1,beta-lactamase_0,P62593,1.05116,NO,155,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.889,-5.571,4.682,,0.049,,B,0.75,-0.9,16.833,16.833,64.69,OAB,-1.62267,0.0500837,0.00135315,1.05116 kka2_1:2_A176K,kka2_1:2_176,Kka2,kka2_1:2,P00552,1.05121,NO,176,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.621,-2.698,1.077,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.295029,0.0083587,1.05121 beta-lactamase_0_I93Y,beta-lactamase_0_93,TEM-1,beta-lactamase_0,P62593,1.05122,NO,93,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.401,-4.112,2.711,,0.128,E,B,0.48,0.44,1.266,,67.83,BHB,-1.873,0.0500837,0.00527066,1.05122 beta-lactamase_39_F149M,beta-lactamase_39_149,TEM-1,beta-lactamase_39,P62593,1.05123,NO,149,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.299,-4.454,3.155,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.0495842,0.00418462,1.05123 beta-lactamase_0_L218T,beta-lactamase_0_218,TEM-1,beta-lactamase_0,P62593,1.05126,NO,218,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.391,-2.536,1.145,,,I,b,0.55,-0.53,28.707,28.707,74.48,OHH,-1.58867,0.0500837,0.00618274,1.05126 beta-lactamase_39_P65Y,beta-lactamase_39_65,TEM-1,beta-lactamase_39,P62593,1.05126,NO,65,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.894,-4.31,3.416,,0.098,E,B,0.52,-0.62,0.623,,40.56,HOH,-1.03233,0.0495842,0.00152776,1.05126 beta-lactamase_0_S221G,beta-lactamase_0_221,TEM-1,beta-lactamase_0,P62593,1.05129,NO,221,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.754,-3.136,1.382,,0.624,H,A,0.27,-0.2,2.914,,74.48,BPH,-1.59967,0.0500837,0.0046094,1.05129 PSD95pdz3_I389Y,PSD95pdz3_389,PSD95pdz3,PSD95pdz3,P31016,1.05129,NO,389,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.628,-3.714,2.086,5.15116,,,,,14.8038,1.498,,87.71,HHH,-1.52167,0.0758425,0.00148097,1.05129 kka2_1:1_L7R,kka2_1:1_7,Kka2,kka2_1:1,P00552,1.05133,NO,7,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.926,-3.722,1.796,,,,,,,18.934,18.934,71.59,OHB,-2.12333,0.520039,0.00269456,1.05133 beta-lactamase_0_I140S,beta-lactamase_0_140,TEM-1,beta-lactamase_0,P62593,1.05136,NO,140,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.733,-3.688,1.955,,0.128,H,A,0.48,0.41,4.714,,73.08,PHO,-1.48733,0.0500837,0.00597777,1.05136 beta-lactamase_39_T112W,beta-lactamase_39_112,TEM-1,beta-lactamase_39,P62593,1.05136,NO,112,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.186,-5.474,3.288,,0.921,T,A,0.22,1.06,2.87,,73.78,HPA,-1.925,0.0495842,0.00531334,1.05136 beta-lactamase_0_Y44L,beta-lactamase_0_44,TEM-1,beta-lactamase_0,P62593,1.05139,NO,44,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-2.547,-2.196,-0.351,,,E,B,0.21,-0.45,1.751,,73.78,OHH,-1.86267,0.0500837,0.00426364,1.05139 kka2_1:2_Q27R,kka2_1:2_27,Kka2,kka2_1:2,P00552,1.05143,NO,27,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-1.659,-3.828,2.169,,0.608,.,A,0.64,0.71,0.521,,65.53,PPP,-1.90733,0.295029,0.00595365,1.05143 kka2_1:8_D52H,kka2_1:8_52,Kka2,kka2_1:8,P00552,1.05143,NO,52,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.271,-4.302,2.031,,0.22,E,B,0.75,0.8,5.447,,71.59,PAH,-2.38367,0.100394,0.00175694,1.05143 kka2_1:8_D52H,kka2_1:8_52,Kka2,kka2_1:8,P00552,1.05143,NO,52,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.271,-4.302,2.031,,0.22,E,B,0.75,0.8,5.447,,71.59,PAH,-2.38367,0.100394,0.00175694,1.05143 kka2_1:8_E161F,kka2_1:8_161,Kka2,kka2_1:8,P00552,1.05144,NO,161,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.581,-4.379,2.798,,0.829,G,A,1.04,2.24,11.923,11.923,92.05,AAB,-1.861,0.100394,0.00760103,1.05144 kka2_1:8_E161F,kka2_1:8_161,Kka2,kka2_1:8,P00552,1.05144,NO,161,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.581,-4.379,2.798,,0.829,G,A,1.04,2.24,11.923,11.923,92.05,AAB,-1.861,0.100394,0.00760103,1.05144 kka2_1:8_G201S,kka2_1:8_201,Kka2,kka2_1:8,P00552,1.05144,NO,201,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.56,-2.438,0.878,,0.149,T,l,0.75,-0.57,2.152,,52.65,POB,-1.92233,0.100394,0.00820117,1.05144 kka2_1:8_G201S,kka2_1:8_201,Kka2,kka2_1:8,P00552,1.05144,NO,201,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.56,-2.438,0.878,,0.149,T,l,0.75,-0.57,2.152,,52.65,POB,-1.92233,0.100394,0.00820117,1.05144 beta-lactamase_0_S241A,beta-lactamase_0_241,TEM-1,beta-lactamase_0,P62593,1.05151,NO,241,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.0500837,0.00452736,1.05151 kka2_1:1_D33R,kka2_1:1_33,Kka2,kka2_1:1,P00552,1.05152,NO,33,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.186,-2.468,0.282,,0.561,S,A,0.75,3.35,2.568,,71.59,PAH,-1.306,0.520039,0.00633568,1.05152 beta-lactamase_625_I285C,beta-lactamase_625_285,TEM-1,beta-lactamase_625,P62593,1.05153,NO,285,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.213352,0.101555,1.05153 kka2_1:8_L174C,kka2_1:8_174,Kka2,kka2_1:8,P00552,1.05153,NO,174,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.952,-4.719,3.767,,,H,A,1.59,-0.31,1.204,,51.89,BHB,-2.08533,0.100394,0.00438501,1.05153 kka2_1:8_L174C,kka2_1:8_174,Kka2,kka2_1:8,P00552,1.05153,NO,174,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.952,-4.719,3.767,,,H,A,1.59,-0.31,1.204,,51.89,BHB,-2.08533,0.100394,0.00438501,1.05153 kka2_1:8_W69Y,kka2_1:8_69,Kka2,kka2_1:8,P00552,1.05153,NO,69,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-0.859,-2.519,1.66,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.100394,0.0012874,1.05153 kka2_1:8_W69Y,kka2_1:8_69,Kka2,kka2_1:8,P00552,1.05153,NO,69,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-0.859,-2.519,1.66,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.100394,0.0012874,1.05153 PSD95pdz3_T387L,PSD95pdz3_387,PSD95pdz3,PSD95pdz3,P31016,1.05153,NO,387,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.391,-2.815,1.424,5.20757,,,,,18.8043,,,,HPH,-1.49533,0.0758425,0.000167911,1.05153 beta-lactamase_39_F228S,beta-lactamase_39_228,TEM-1,beta-lactamase_39,P62593,1.05156,NO,228,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-2.342,-3.492,1.15,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.0495842,0.0046669,1.05156 beta-lactamase_156_H110D,beta-lactamase_156_110,TEM-1,beta-lactamase_156,P62593,1.05157,NO,110,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-1.706,-3.678,1.972,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.111618,0.00441499,1.05157 beta-lactamase_39_K32Q,beta-lactamase_39_32,TEM-1,beta-lactamase_39,P62593,1.05159,NO,32,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.984,-2.601,0.617,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.0495842,0.00401283,1.05159 beta-lactamase_L19C,beta-lactamase_19,TEM-1,beta-lactamase,P62593,1.0516,NO,19,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.682,-4.8,3.118,,,,,,,4.261,,93.01,OHO,-1.894,0.221079,0.00215974,1.0516 kka2_1:8_L184Q,kka2_1:8_184,Kka2,kka2_1:8,P00552,1.05162,NO,184,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.496,-4.197,2.701,,0.489,E,B,0.55,-0.06,4.495,,63.26,AHH,-1.24833,0.100394,0.00518742,1.05162 kka2_1:8_L184Q,kka2_1:8_184,Kka2,kka2_1:8,P00552,1.05162,NO,184,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.496,-4.197,2.701,,0.489,E,B,0.55,-0.06,4.495,,63.26,AHH,-1.24833,0.100394,0.00518742,1.05162 gb1_A274F,gb1_274,gb1,gb1,P06654,1.05171,NO,274,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.728,-4.067,2.339,,,,,,,4.162,4.162,11.83,AHP,-1.81767,0.177985,0.0068419,1.05171 beta-lactamase_39_T187R,beta-lactamase_39_187,TEM-1,beta-lactamase_39,P62593,1.05174,NO,187,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.401,-3.885,2.484,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.0495842,0.00491782,1.05174 beta-lactamase_0_R242V,beta-lactamase_0_242,TEM-1,beta-lactamase_0,P62593,1.05177,NO,242,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.0500837,0.00452879,1.05177 beta-lactamase_39_R202I,beta-lactamase_39_202,TEM-1,beta-lactamase_39,P62593,1.05179,NO,202,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.292,-4.027,2.735,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.0495842,0.00321899,1.05179 PSD95pdz3_P346S,PSD95pdz3_346,PSD95pdz3,PSD95pdz3,P31016,1.05179,NO,346,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.236,-3.067,1.831,5.02406,,,,,14.6629,,,,OOH,-1.18367,0.0758425,0.000758563,1.05179 beta-lactamase_39_T186D,beta-lactamase_39_186,TEM-1,beta-lactamase_39,P62593,1.05181,NO,186,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.522,-2.935,0.413,,0.396,H,A,0.22,-0.28,0.515,,77.62,HPP,-1.77633,0.0495842,0.00485034,1.05181 beta-lactamase_39_E26P,beta-lactamase_39_26,TEM-1,beta-lactamase_39,P62593,1.05184,NO,26,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.454,-2.862,0.408,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.0495842,0.00297948,1.05184 PSD95pdz3_R313W,PSD95pdz3_313,PSD95pdz3,PSD95pdz3,P31016,1.05186,NO,313,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.582,-5.004,3.422,6.63563,,,,,18.3955,,,,BBH,-1.59733,0.0758425,0.000840067,1.05186 PSD95pdz3_D366H,PSD95pdz3_366,PSD95pdz3,PSD95pdz3,P31016,1.05188,NO,366,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.264,-4.137,2.873,5.55684,,,,,20.2375,,,,HAH,-1.401,0.0758425,0.000481272,1.05188 kka2_1:2_V214L,kka2_1:2_214,Kka2,kka2_1:2,P00552,1.05189,NO,214,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.261,-2.012,0.751,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.295029,0.00692782,1.05189 beta-lactamase_0_M270L,beta-lactamase_0_270,TEM-1,beta-lactamase_0,P62593,1.05194,NO,270,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.0500837,0.00767762,1.05194 PSD95pdz3_R312K,PSD95pdz3_312,PSD95pdz3,PSD95pdz3,P31016,1.05194,NO,312,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.582,-2.464,0.882,5.76826,,,,,12.2409,,,,OBB,-1.46667,0.0758425,0.00196255,1.05194 beta-lactamase_0_D271W,beta-lactamase_0_271,TEM-1,beta-lactamase_0,P62593,1.05195,NO,271,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.0500837,0.00752082,1.05195 PSD95pdz3_A343G,PSD95pdz3_343,PSD95pdz3,PSD95pdz3,P31016,1.05196,NO,343,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.307,-2.59,1.283,5.585,,,,,14.728,,,,HHO,-1.22067,0.0758425,0.000798084,1.05196 kka2_1:8_D180E,kka2_1:8_180,Kka2,kka2_1:8,P00552,1.052,NO,180,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.416,-2.535,0.119,,1.03,S,a,0.75,1.5,14.668,14.668,71.59,OAO,-2.02933,0.100394,0.00756412,1.052 kka2_1:8_D180E,kka2_1:8_180,Kka2,kka2_1:8,P00552,1.052,NO,180,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.416,-2.535,0.119,,1.03,S,a,0.75,1.5,14.668,14.668,71.59,OAO,-2.02933,0.100394,0.00756412,1.052 beta-lactamase_0_P255G,beta-lactamase_0_255,TEM-1,beta-lactamase_0,P62593,1.05201,NO,255,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.0500837,0.00499612,1.05201 beta-lactamase_0_A230Y,beta-lactamase_0_230,TEM-1,beta-lactamase_0,P62593,1.05204,NO,230,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.154,-4.312,3.158,,0.01,E,B,0.46,-1.17,2.179,,50,HHA,-1.079,0.0500837,0.00516841,1.05204 kka2_1:8_H135Q,kka2_1:8_135,Kka2,kka2_1:8,P00552,1.05205,NO,135,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-1.331,-2.136,0.805,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.100394,0.00532566,1.05205 kka2_1:8_H135Q,kka2_1:8_135,Kka2,kka2_1:8,P00552,1.05205,NO,135,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-1.331,-2.136,0.805,,0.071,,a,0.87,0.65,3.574,,53.03,ABP,-1.77367,0.100394,0.00532566,1.05205 kka2_1:1_K138R,kka2_1:1_138,Kka2,kka2_1:1,P00552,1.05207,NO,138,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-2.5,-3.18,0.68,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.520039,0.00628542,1.05207 PSD95pdz3_D332Y,PSD95pdz3_332,PSD95pdz3,PSD95pdz3,P31016,1.0521,NO,332,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.264,-4.069,2.805,6.09878,,,,,48.762,,,,AAO,-1.22533,0.0758425,0.000937818,1.0521 kka2_1:4_A229H,kka2_1:4_229,Kka2,kka2_1:4,P00552,1.05212,NO,229,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.739,-3.451,1.712,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.168804,0.00942138,1.05212 kka2_1:4_V242Q,kka2_1:4_242,Kka2,kka2_1:4,P00552,1.05212,NO,242,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-2.687,-2.985,0.298,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.168804,0.0102575,1.05212 beta-lactamase_0_W163D,beta-lactamase_0_163,TEM-1,beta-lactamase_0,P62593,1.05213,NO,163,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-1.843,-3.903,2.06,,0.467,,B,0.47,-0.5,13.843,13.843,63.99,BHA,-1.269,0.0500837,0.00418955,1.05213 beta-lactamase_0_R242E,beta-lactamase_0_242,TEM-1,beta-lactamase_0,P62593,1.05214,NO,242,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.0500837,0.00452879,1.05214 PSD95pdz3_F337M,PSD95pdz3_337,PSD95pdz3,PSD95pdz3,P31016,1.05216,NO,337,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.524,-3.937,2.413,5.22838,,,,,13.4936,,,,HHH,-1.59467,0.0758425,0.000875287,1.05216 E1_Ubiquitin_Q40E,E1_Ubiquitin_40,Uba1,E1_Ubiquitin,P0CG63,1.05217,NO,40,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-1.48,-2.048,0.568,,0.387,G,A,,0.03,,,,OPP,-1.365,0.18783,0.0037961,1.05217 E1_Ubiquitin_T68R,E1_Ubiquitin_68,Uba1,E1_Ubiquitin,P0CG63,1.05217,NO,68,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,,,,,,,,,,,,,OPH,-1.039,0.18783,0.00314321,1.05217 kka2_1:8_G55L,kka2_1:8_55,Kka2,kka2_1:8,P00552,1.05217,NO,55,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.625,-2.999,1.374,,0.517,S,b,0.29,1.19,8.881,,63.64,POH,-2.05967,0.100394,0.00667877,1.05217 kka2_1:8_G55L,kka2_1:8_55,Kka2,kka2_1:8,P00552,1.05217,NO,55,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.625,-2.999,1.374,,0.517,S,b,0.29,1.19,8.881,,63.64,POH,-2.05967,0.100394,0.00667877,1.05217 beta-lactamase_156_L284M,beta-lactamase_156_284,TEM-1,beta-lactamase_156,P62593,1.05219,NO,284,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.981,,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.111618,0.0686156,1.05219 beta-lactamase_0_A132V,beta-lactamase_0_132,TEM-1,beta-lactamase_0,P62593,1.05223,NO,132,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.9,-2.46,1.56,,,H,A,0.46,-0.93,2.249,,64.69,PHH,-1.138,0.0500837,0.000962524,1.05223 kka2_1:4_L184Q,kka2_1:4_184,Kka2,kka2_1:4,P00552,1.05226,NO,184,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.496,-4.197,2.701,,0.489,E,B,1.59,-0.06,4.495,,63.26,AHH,-1.24833,0.168804,0.00518742,1.05226 kka2_1:8_M1T,kka2_1:8_1,Kka2,kka2_1:8,P00552,1.05231,NO,1,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.787,-3.152,1.365,,,,,,,16.725,16.725,62.12,NAHH,-1.787,0.100394,0.00251939,1.05231 kka2_1:8_M1T,kka2_1:8_1,Kka2,kka2_1:8,P00552,1.05231,NO,1,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.787,-3.152,1.365,,,,,,,16.725,16.725,62.12,NAHH,-1.787,0.100394,0.00251939,1.05231 beta-lactamase_2500_K190Q,beta-lactamase_2500_190,TEM-1,beta-lactamase_2500,P62593,1.05239,NO,190,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.994,-2.883,0.889,,0.371,H,A,2.34,0.16,29.753,29.753,77.62,BBH,-1.64167,0.361275,0.00574527,1.05239 kka2_1:4_P45M,kka2_1:4_45,Kka2,kka2_1:4,P00552,1.0524,NO,45,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.774,-4.81,3.036,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.168804,0.00590481,1.0524 kka2_1:8_R253G,kka2_1:8_253,Kka2,kka2_1:8,P00552,1.05242,NO,253,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.356,-3.453,2.097,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.100394,0.0144195,1.05242 kka2_1:8_R253G,kka2_1:8_253,Kka2,kka2_1:8,P00552,1.05242,NO,253,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.356,-3.453,2.097,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.100394,0.0144195,1.05242 PSD95pdz3_R354N,PSD95pdz3_354,PSD95pdz3,PSD95pdz3,P31016,1.05243,NO,354,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.582,-3.13,1.548,6.21887,,,,,23.7791,,,,HBB,-1.44833,0.0758425,0.000650924,1.05243 beta-lactamase_0_H24A,beta-lactamase_0_24,TEM-1,beta-lactamase_0,P62593,1.05245,NO,24,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-2.481,-2.265,-0.216,,,,,,,2.708,,93.01,OBO,-2.0035,0.0500837,0.00238894,1.05245 kka2_1:4_A137N,kka2_1:4_137,Kka2,kka2_1:4,P00552,1.05247,NO,137,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.156,-4.15,1.994,,0.029,H,A,0.46,0.34,2.227,,63.26,PHB,-2.559,0.168804,0.00515054,1.05247 kka2_1:8_D157S,kka2_1:8_157,Kka2,kka2_1:8,P00552,1.05252,NO,157,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.993,-2.619,1.626,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.100394,0.0042313,1.05252 kka2_1:8_D157S,kka2_1:8_157,Kka2,kka2_1:8,P00552,1.05252,NO,157,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.993,-2.619,1.626,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.100394,0.0042313,1.05252 beta-lactamase_0_T158C,beta-lactamase_0_158,TEM-1,beta-lactamase_0,P62593,1.05253,NO,158,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.116,-4.748,3.632,,0.036,,B,0.22,-0.85,1.041,,69.58,HPB,-1.269,0.0500837,0.00341825,1.05253 kka2_1:2_A87S,kka2_1:2_87,Kka2,kka2_1:2,P00552,1.05254,NO,87,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.917,-2.911,0.994,,1.039,S,L,0.46,1.57,22.675,22.675,65.53,AHO,-1.822,0.295029,0.00791281,1.05254 kka2_1:4_H8T,kka2_1:4_8,Kka2,kka2_1:4,P00552,1.0526,NO,8,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-2.759,-3.343,0.584,,,,,,,,,71.59,HBH,-2.25467,0.168804,0.00256422,1.0526 kka2_1:4_K175P,kka2_1:4_175,Kka2,kka2_1:4,P00552,1.0526,NO,175,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-2.897,-4.168,1.271,,0.579,H,A,1.3,0.51,15.629,15.629,71.59,HBH,-1.82333,0.168804,0.00693093,1.0526 kka2_1:8_L165Y,kka2_1:8_165,Kka2,kka2_1:8,P00552,1.05262,NO,165,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-2.453,-4.292,1.839,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.100394,0.00801161,1.05262 kka2_1:8_L165Y,kka2_1:8_165,Kka2,kka2_1:8,P00552,1.05262,NO,165,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-2.453,-4.292,1.839,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.100394,0.00801161,1.05262 kka2_1:8_L232W,kka2_1:8_232,Kka2,kka2_1:8,P00552,1.05262,NO,232,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.514,-3.426,1.912,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.100394,0.00800103,1.05262 kka2_1:8_L232W,kka2_1:8_232,Kka2,kka2_1:8,P00552,1.05262,NO,232,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.514,-3.426,1.912,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.100394,0.00800103,1.05262 kka2_1:4_R145N,kka2_1:4_145,Kka2,kka2_1:4,P00552,1.05264,NO,145,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.804,-3.787,1.983,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.168804,0.00846663,1.05264 beta-lactamase_39_T27K,beta-lactamase_39_27,TEM-1,beta-lactamase_39,P62593,1.05266,NO,27,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.905,-3.516,1.611,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.0495842,0.00306559,1.05266 PSD95pdz3_G319M,PSD95pdz3_319,PSD95pdz3,PSD95pdz3,P31016,1.05269,NO,319,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.008,-4.612,3.604,4.95387,,,,,18.8725,,,,BOP,-1.36967,0.0758425,0.00109317,1.05269 beta-lactamase_39_A211T,beta-lactamase_39_211,TEM-1,beta-lactamase_39,P62593,1.0527,NO,211,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.896,-2.901,1.005,,0.369,T,A,0.46,-0.69,1.419,,77.62,AHA,-1.94633,0.0495842,0.00648183,1.0527 kka2_1:8_L243F,kka2_1:8_243,Kka2,kka2_1:8,P00552,1.0527,NO,243,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-2.651,-4.372,1.721,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.100394,0.00884927,1.0527 kka2_1:8_L243F,kka2_1:8_243,Kka2,kka2_1:8,P00552,1.0527,NO,243,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-2.651,-4.372,1.721,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.100394,0.00884927,1.0527 beta-lactamase_0_L55V,beta-lactamase_0_55,TEM-1,beta-lactamase_0,P62593,1.05272,NO,55,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.86,-2.346,0.486,,0.372,E,A,0.55,-0.36,1.967,,63.99,HHA,-2.247,0.0500837,0.00403741,1.05272 kka2_1:2_L57R,kka2_1:2_57,Kka2,kka2_1:2,P00552,1.05273,NO,57,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.898,-4.138,2.24,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.295029,0.00723769,1.05273 kka2_1:8_R202I,kka2_1:8_202,Kka2,kka2_1:8,P00552,1.05273,NO,202,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.761,-3.279,1.518,,0.607,E,B,1.2,0.48,1.409,,52.27,OBH,-1.41067,0.100394,0.00696498,1.05273 kka2_1:8_R202I,kka2_1:8_202,Kka2,kka2_1:8,P00552,1.05273,NO,202,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.761,-3.279,1.518,,0.607,E,B,1.2,0.48,1.409,,52.27,OBH,-1.41067,0.100394,0.00696498,1.05273 kka2_1:8_V46F,kka2_1:8_46,Kka2,kka2_1:8,P00552,1.05275,NO,46,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-2.62,-3.464,0.844,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.100394,0.00631301,1.05275 kka2_1:8_V46F,kka2_1:8_46,Kka2,kka2_1:8,P00552,1.05275,NO,46,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-2.62,-3.464,0.844,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.100394,0.00631301,1.05275 beta-lactamase_39_F149C,beta-lactamase_39_149,TEM-1,beta-lactamase_39,P62593,1.05281,NO,149,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.299,-4.94,3.641,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.0495842,0.00418462,1.05281 PSD95pdz3_D366T,PSD95pdz3_366,PSD95pdz3,PSD95pdz3,P31016,1.05281,NO,366,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.264,-3.103,1.839,5.55684,,,,,20.2375,,,,HAH,-1.401,0.0758425,0.000481272,1.05281 kka2_1:8_K112Q,kka2_1:8_112,Kka2,kka2_1:8,P00552,1.05282,NO,112,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-2.491,-2.826,0.335,,0.076,H,A,1.3,-1.37,10.58,10.58,56.06,ABH,-2.00133,0.100394,0.00645389,1.05282 kka2_1:8_K112Q,kka2_1:8_112,Kka2,kka2_1:8,P00552,1.05282,NO,112,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-2.491,-2.826,0.335,,0.076,H,A,1.3,-1.37,10.58,10.58,56.06,ABH,-2.00133,0.100394,0.00645389,1.05282 kka2_1:4_G181C,kka2_1:4_181,Kka2,kka2_1:4,P00552,1.05283,NO,181,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-2.698,-5.203,2.505,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.168804,0.00728319,1.05283 PSD95pdz3_G322P,PSD95pdz3_322,PSD95pdz3,PSD95pdz3,P31016,1.05285,NO,322,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.008,-3.561,2.553,5.24791,,,,,16.3275,,,,POH,-1.24867,0.0758425,0.00105821,1.05285 beta-lactamase_0_T158S,beta-lactamase_0_158,TEM-1,beta-lactamase_0,P62593,1.05287,NO,158,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.116,-1.795,0.679,,0.036,,B,0.22,-0.85,1.041,,69.58,HPB,-1.269,0.0500837,0.00341825,1.05287 kka2_1:4_L57W,kka2_1:4_57,Kka2,kka2_1:4,P00552,1.05289,NO,57,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.898,-3.389,1.491,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.168804,0.00723769,1.05289 kka2_1:8_E96P,kka2_1:8_96,Kka2,kka2_1:8,P00552,1.0529,NO,96,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.573,-3.855,1.282,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.100394,0.00369441,1.0529 kka2_1:8_E96P,kka2_1:8_96,Kka2,kka2_1:8,P00552,1.0529,NO,96,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.573,-3.855,1.282,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.100394,0.00369441,1.0529 beta-lactamase_0_L100K,beta-lactamase_0_100,TEM-1,beta-lactamase_0,P62593,1.05291,NO,100,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.218,-3.837,2.619,,0.343,,B,0.55,0.13,1.373,,63.29,AHH,-1.23467,0.0500837,0.00413885,1.05291 kka2_1:8_E111R,kka2_1:8_111,Kka2,kka2_1:8,P00552,1.05291,NO,111,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.28,-2.316,0.036,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.100394,0.00746789,1.05291 kka2_1:8_E111R,kka2_1:8_111,Kka2,kka2_1:8,P00552,1.05291,NO,111,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.28,-2.316,0.036,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.100394,0.00746789,1.05291 kka2_1:8_G164L,kka2_1:8_164,Kka2,kka2_1:8,P00552,1.05294,NO,164,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.869,-3.829,2.96,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.100394,0.00442091,1.05294 kka2_1:8_G164L,kka2_1:8_164,Kka2,kka2_1:8,P00552,1.05294,NO,164,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.869,-3.829,2.96,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.100394,0.00442091,1.05294 beta-lactamase_156_E26W,beta-lactamase_156_26,TEM-1,beta-lactamase_156,P62593,1.05297,NO,26,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.454,-5.402,2.948,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.111618,0.00297948,1.05297 kka2_1:8_G74K,kka2_1:8_74,Kka2,kka2_1:8,P00552,1.053,NO,74,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.18,-3.609,2.429,,0.621,T,l,0.29,0.2,2.014,,64.39,POH,-1.91667,0.100394,0.00587035,1.053 kka2_1:8_G74K,kka2_1:8_74,Kka2,kka2_1:8,P00552,1.053,NO,74,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.18,-3.609,2.429,,0.621,T,l,0.29,0.2,2.014,,64.39,POH,-1.91667,0.100394,0.00587035,1.053 kka2_1:2_L243C,kka2_1:2_243,Kka2,kka2_1:2,P00552,1.05301,NO,243,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-2.651,-2.68,0.029,,0.277,H,A,1.59,-0.67,13.165,13.165,92.05,HHH,-2.03767,0.295029,0.00884927,1.05301 kka2_1:2_D250C,kka2_1:2_250,Kka2,kka2_1:2,P00552,1.05304,NO,250,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.015,-5.204,4.189,,0.274,.,b,0.75,-0.46,3.796,,51.89,OAP,-1.83933,0.295029,0.0177103,1.05304 beta-lactamase_L199I,beta-lactamase_199,TEM-1,beta-lactamase,P62593,1.05307,NO,199,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-2.942,-3.16,0.218,5.57712,0.832,H,A,0.82,0.42,15.302,15.302,77.62,PHH,-2.32933,0.221079,0.0048649,1.05307 beta-lactamase_Q97F,beta-lactamase_97,TEM-1,beta-lactamase,P62593,1.05307,NO,97,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.072,-4.44,2.368,6.30204,0.823,G,A,1.1,2.42,1.157,,77.62,PPP,-2.43833,0.221079,0.0045116,1.05307 kka2_1:2_S114G,kka2_1:2_114,Kka2,kka2_1:2,P00552,1.05309,NO,114,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.527,-2.602,0.075,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.295029,0.00705262,1.05309 PSD95pdz3_A343E,PSD95pdz3_343,PSD95pdz3,PSD95pdz3,P31016,1.05309,NO,343,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.307,-3.122,1.815,5.585,,,,,14.728,,,,HHO,-1.22067,0.0758425,0.000798084,1.05309 beta-lactamase_39_I171S,beta-lactamase_39_171,TEM-1,beta-lactamase_39,P62593,1.05314,NO,171,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-2.431,-2.869,0.438,,0.361,,B,0.48,0.53,16.954,16.954,77.62,HHO,-1.55533,0.0495842,0.00623355,1.05314 beta-lactamase_39_K109F,beta-lactamase_39_109,TEM-1,beta-lactamase_39,P62593,1.05318,NO,109,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.734,-4.437,2.703,,0.787,G,A,2.34,2.21,7.243,,72.73,ABB,-1.63333,0.0495842,0.00462493,1.05318 kka2_1:4_E231S,kka2_1:4_231,Kka2,kka2_1:4,P00552,1.05318,NO,231,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.002,-3.227,1.225,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.168804,0.00732383,1.05318 beta-lactamase_39_F228I,beta-lactamase_39_228,TEM-1,beta-lactamase_39,P62593,1.05319,NO,228,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-2.342,-3.049,0.707,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.0495842,0.0046669,1.05319 beta-lactamase_0_S233P,beta-lactamase_0_233,TEM-1,beta-lactamase_0,P62593,1.05324,NO,233,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.886,-2.778,0.892,,0.016,E,B,0.27,-1.01,3.579,,77.62,BPO,-1.17267,0.0500837,0.00311415,1.05324 kka2_1:8_P249R,kka2_1:8_249,Kka2,kka2_1:8,P00552,1.05328,NO,249,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.867,-3.291,1.424,,0.406,.,B,0.52,-0.01,1.699,,92.05,HOA,-1.66867,0.100394,0.011045,1.05328 kka2_1:8_P249R,kka2_1:8_249,Kka2,kka2_1:8,P00552,1.05328,NO,249,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.867,-3.291,1.424,,0.406,.,B,0.52,-0.01,1.699,,92.05,HOA,-1.66867,0.100394,0.011045,1.05328 beta-lactamase_0_N98H,beta-lactamase_0_98,TEM-1,beta-lactamase_0,P62593,1.05329,NO,98,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-2.973,-3.344,0.371,,0.963,G,A,0.61,1.35,14.853,14.853,77.62,PPA,-2.07867,0.0500837,0.00505389,1.05329 gb1_D272S,gb1_272,gb1,gb1,P06654,1.05334,NO,272,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.457,-2.965,1.508,,,,,,,0.234,,11.83,HAA,-1.54533,0.177985,0.00218257,1.05334 gb1_Q228Y,gb1_228,gb1,gb1,P06654,1.05334,NO,228,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,,,,,,,,,,,,,OPH,-1.282,0.177985,0.00391043,1.05334 kka2_1:4_D154H,kka2_1:4_154,Kka2,kka2_1:4,P00552,1.05334,NO,154,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.876,-4.446,3.57,,0.457,,b,0.29,1.48,15.641,15.641,52.65,HAP,-1.52467,0.168804,0.00292633,1.05334 beta-lactamase_39_V106Y,beta-lactamase_39_106,TEM-1,beta-lactamase_39,P62593,1.05342,NO,106,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.218,-3.895,2.677,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.0495842,0.00304168,1.05342 gb1_D248T,gb1_248,gb1,gb1,P06654,1.05345,NO,248,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.569,-2.982,1.413,,,,,,,0.344,,11.83,HAH,-1.673,0.177985,0.001865,1.05345 kka2_1:4_I29H,kka2_1:4_29,Kka2,kka2_1:4,P00552,1.05349,NO,29,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.692,-4.894,3.202,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.168804,0.00619521,1.05349 beta-lactamase_0_Q37I,beta-lactamase_0_37,TEM-1,beta-lactamase_0,P62593,1.05351,NO,37,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.134,-4.024,1.89,,0.613,H,A,0.64,1.98,4.001,,73.08,APH,-2.06967,0.0500837,0.00425833,1.05351 kka2_1:8_E161Y,kka2_1:8_161,Kka2,kka2_1:8,P00552,1.05351,NO,161,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.581,-4.394,2.813,,0.829,G,A,1.04,2.24,11.923,11.923,92.05,AAB,-1.861,0.100394,0.00760103,1.05351 kka2_1:8_E161Y,kka2_1:8_161,Kka2,kka2_1:8,P00552,1.05351,NO,161,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.581,-4.394,2.813,,0.829,G,A,1.04,2.24,11.923,11.923,92.05,AAB,-1.861,0.100394,0.00760103,1.05351 beta-lactamase_I171N,beta-lactamase_171,TEM-1,beta-lactamase,P62593,1.05355,NO,171,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-2.431,-3.904,1.473,5.22771,0.361,,B,1,0.53,1.66,,77.62,HHO,-1.55533,0.221079,0.00623355,1.05355 kka2_1:4_R239L,kka2_1:4_239,Kka2,kka2_1:4,P00552,1.05355,NO,239,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.949,-2.571,-0.378,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.168804,0.00835326,1.05355 kka2_1:8_A150N,kka2_1:8_150,Kka2,kka2_1:8,P00552,1.05357,NO,150,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.949,-3.852,2.903,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.100394,0.0045009,1.05357 kka2_1:8_A150N,kka2_1:8_150,Kka2,kka2_1:8,P00552,1.05357,NO,150,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.949,-3.852,2.903,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.100394,0.0045009,1.05357 PSD95pdz3_S320N,PSD95pdz3_320,PSD95pdz3,PSD95pdz3,P31016,1.05357,NO,320,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.519,-2.905,1.386,5.81757,,,,,21.4517,,,,OPP,-1.306,0.0758425,0.00108158,1.05357 beta-lactamase_39_V214T,beta-lactamase_39_214,TEM-1,beta-lactamase_39,P62593,1.05359,NO,214,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.299,-1.73,0.431,,0.375,S,A,0.44,-0.44,18.838,18.838,74.48,BHH,-1.53733,0.0495842,0.00628442,1.05359 kka2_1:8_F37A,kka2_1:8_37,Kka2,kka2_1:8,P00552,1.05363,NO,37,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.427,-2.571,1.144,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.100394,0.00586193,1.05363 kka2_1:8_F37A,kka2_1:8_37,Kka2,kka2_1:8,P00552,1.05363,NO,37,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.427,-2.571,1.144,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.100394,0.00586193,1.05363 gb1_T277N,gb1_277,gb1,gb1,P06654,1.05368,NO,277,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.771,-3.453,1.682,,,,,,,0.824,,35.71,BPH,-1.54833,0.177985,0.00348258,1.05368 beta-lactamase_0_E279R,beta-lactamase_0_279,TEM-1,beta-lactamase_0,P62593,1.05369,NO,279,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.0500837,0.0192826,1.05369 kka2_1:1_L60M,kka2_1:1_60,Kka2,kka2_1:1,P00552,1.05371,NO,60,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.997,-2.995,1.998,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.520039,0.00262176,1.05371 kka2_1:4_V84G,kka2_1:4_84,Kka2,kka2_1:4,P00552,1.05371,NO,84,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-2.279,-3.558,1.279,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.168804,0.00724019,1.05371 beta-lactamase_39_E210V,beta-lactamase_39_210,TEM-1,beta-lactamase_39,P62593,1.05373,NO,210,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.319,-1.881,-0.438,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.0495842,0.00663582,1.05373 kka2_1:1_F20E,kka2_1:1_20,Kka2,kka2_1:1,P00552,1.05375,NO,20,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-3.354,-2.8,-0.554,,0.935,T,B,0.58,-0.41,1.657,,92.05,HHO,-1.992,0.520039,0.00701744,1.05375 beta-lactamase_39_E87K,beta-lactamase_39_87,TEM-1,beta-lactamase_39,P62593,1.05377,NO,87,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.421,-2.715,1.294,,0.048,,B,1.04,0.92,15.231,15.231,64.69,PAP,-1.969,0.0495842,0.00337888,1.05377 gb1_E241I,gb1_241,gb1,gb1,P06654,1.0538,NO,241,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.672,-3.571,1.899,,,,,,,0.344,,11.83,OAP,-1.27933,0.177985,0.00250604,1.0538 beta-lactamase_0_M270N,beta-lactamase_0_270,TEM-1,beta-lactamase_0,P62593,1.05386,NO,270,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.0500837,0.00767762,1.05386 beta-lactamase_0_G85I,beta-lactamase_0_85,TEM-1,beta-lactamase_0,P62593,1.05387,NO,85,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.011,-4.226,3.215,,0.805,T,l,0.29,1.7,2.25,,63.64,HOP,-1.68733,0.0500837,0.00252173,1.05387 beta-lactamase_0_N152C,beta-lactamase_0_152,TEM-1,beta-lactamase_0,P62593,1.05393,NO,152,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-2.757,-5.071,2.314,,0.863,H,A,0.61,0.92,2.151,,77.62,BPH,-2.97,0.0500837,0.00471429,1.05393 E1_Ubiquitin_F45K,E1_Ubiquitin_45,Uba1,E1_Ubiquitin,P0CG63,1.05393,NO,45,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.149,-3.724,2.575,,0.26,E,B,,-0.99,,,,HHH,-1.316,0.18783,0.00193245,1.05393 E1_Ubiquitin_L73Q,E1_Ubiquitin_73,Uba1,E1_Ubiquitin,P0CG63,1.05393,NO,73,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.039,-3.941,2.902,,0.518,,B,1.3,1,,,,BHB,-1.175,0.18783,0.00111236,1.05393 E1_Ubiquitin_Q40K,E1_Ubiquitin_40,Uba1,E1_Ubiquitin,P0CG63,1.05393,NO,40,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-1.48,-2.993,1.513,,0.387,G,A,,0.03,,,,OPP,-1.365,0.18783,0.0037961,1.05393 beta-lactamase_625_D212S,beta-lactamase_625_212,TEM-1,beta-lactamase_625,P62593,1.05395,NO,212,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.624,-2.471,0.847,,0.037,,b,0.75,-0.58,1.516,,74.48,HAB,-1.77667,0.213352,0.00644302,1.05395 beta-lactamase_39_F149N,beta-lactamase_39_149,TEM-1,beta-lactamase_39,P62593,1.05397,NO,149,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.299,-4.055,2.756,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.0495842,0.00418462,1.05397 kka2_1:2_D156N,kka2_1:2_156,Kka2,kka2_1:2,P00552,1.05404,NO,156,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.696,-3.632,1.936,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.295029,0.00926998,1.05404 kka2_1:4_P76M,kka2_1:4_76,Kka2,kka2_1:4,P00552,1.05404,NO,76,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.449,-4.717,3.268,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.168804,0.00625685,1.05404 beta-lactamase_156_R92Y,beta-lactamase_156_92,TEM-1,beta-lactamase_156,P62593,1.05407,NO,92,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.718,-4.31,2.592,,0.479,E,B,1.2,1.36,19.112,19.112,65.38,BBH,-1.50367,0.111618,0.00429626,1.05407 kka2_1:4_E235T,kka2_1:4_235,Kka2,kka2_1:4,P00552,1.05407,NO,235,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.955,-3.009,1.054,,0.631,H,A,1.04,0.12,23.175,23.175,65.53,OAH,-2.07267,0.168804,0.0102806,1.05407 beta-lactamase_0_W227N,beta-lactamase_0_227,TEM-1,beta-lactamase_0,P62593,1.05408,NO,227,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-0.982,-4.236,3.254,,0.272,,B,0.47,-0.29,3.782,,74.48,OHH,-1.595,0.0500837,0.00226019,1.05408 kka2_1:4_E235W,kka2_1:4_235,Kka2,kka2_1:4,P00552,1.05411,NO,235,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.955,-5.585,3.63,,0.631,H,A,1.04,0.12,23.175,23.175,65.53,OAH,-2.07267,0.168804,0.0102806,1.05411 beta-lactamase_0_K32M,beta-lactamase_0_32,TEM-1,beta-lactamase_0,P62593,1.05412,NO,32,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.984,-4.613,2.629,,0.563,H,A,2.34,0.34,0.418,,73.08,HBA,-2.04233,0.0500837,0.00401283,1.05412 beta-lactamase_39_G253M,beta-lactamase_39_253,TEM-1,beta-lactamase_39,P62593,1.05413,NO,253,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.0495842,0.00786358,1.05413 gb1_E245T,gb1_245,gb1,gb1,P06654,1.05414,NO,245,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.725,-3.157,0.432,,,,,,,0.712,,45.54,PAH,-1.84567,0.177985,0.00158611,1.05414 gb1_T270G,gb1_270,gb1,gb1,P06654,1.05414,NO,270,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-3.15,-3.004,-0.146,,,,,,,1.326,,45.54,HPH,-1.843,0.177985,0.00223707,1.05414 beta-lactamase_625_Q203F,beta-lactamase_625_203,TEM-1,beta-lactamase_625,P62593,1.05417,NO,203,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.168,-4.379,2.211,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.213352,0.00631514,1.05417 kka2_1:4_A9E,kka2_1:4_9,Kka2,kka2_1:4,P00552,1.05417,NO,9,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.079,-3.534,1.455,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.168804,0.00273264,1.05417 kka2_1:8_S204K,kka2_1:8_204,Kka2,kka2_1:8,P00552,1.05418,NO,204,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.353,-3.511,2.158,,0.144,E,A,0.27,-1.2,0.368,,65.53,HPO,-0.953333,0.100394,0.00881794,1.05418 kka2_1:8_S204K,kka2_1:8_204,Kka2,kka2_1:8,P00552,1.05418,NO,204,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.353,-3.511,2.158,,0.144,E,A,0.27,-1.2,0.368,,65.53,HPO,-0.953333,0.100394,0.00881794,1.05418 beta-lactamase_0_D212K,beta-lactamase_0_212,TEM-1,beta-lactamase_0,P62593,1.05427,NO,212,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.624,-3.581,1.957,,0.037,,b,0.75,-0.58,3.34,,74.48,HAB,-1.77667,0.0500837,0.00644302,1.05427 beta-lactamase_625_E272T,beta-lactamase_625_272,TEM-1,beta-lactamase_625,P62593,1.05433,NO,272,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.213352,0.00545371,1.05433 beta-lactamase_0_M153C,beta-lactamase_0_153,TEM-1,beta-lactamase_0,P62593,1.05435,NO,153,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-3.193,-4.79,1.597,,0.14,T,A,0.55,-0.11,3.826,,77.62,PHO,-2.25767,0.0500837,0.00509109,1.05435 gb1_E245S,gb1_245,gb1,gb1,P06654,1.05437,NO,245,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.725,-2.896,0.171,,,,,,,0.712,,45.54,PAH,-1.84567,0.177985,0.00158611,1.05437 beta-lactamase_0_N173T,beta-lactamase_0_173,TEM-1,beta-lactamase_0,P62593,1.0544,NO,173,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-2.663,-3.589,0.926,,1.044,T,l,0.61,1.25,1.133,,77.62,OPA,-1.46633,0.0500837,0.0033769,1.0544 PSD95pdz3_S350T,PSD95pdz3_350,PSD95pdz3,PSD95pdz3,P31016,1.05446,NO,350,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.519,-2.653,1.134,4.97629,,,,,25.01,,,,HPO,-1.29133,0.0758425,0.000704883,1.05446 beta-lactamase_0_D155S,beta-lactamase_0_155,TEM-1,beta-lactamase_0,P62593,1.05448,NO,155,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.889,-3.185,2.296,,0.049,,B,0.75,-0.9,16.833,16.833,64.69,OAB,-1.62267,0.0500837,0.00135315,1.05448 beta-lactamase_0_K232P,beta-lactamase_0_232,TEM-1,beta-lactamase_0,P62593,1.05449,NO,232,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.012,-3.752,2.74,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.0500837,0.00313441,1.05449 kka2_1:8_Q100R,kka2_1:8_100,Kka2,kka2_1:8,P00552,1.05449,NO,100,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.77,-2.202,-0.568,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.100394,0.0066405,1.05449 kka2_1:8_Q100R,kka2_1:8_100,Kka2,kka2_1:8,P00552,1.05449,NO,100,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.77,-2.202,-0.568,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.100394,0.0066405,1.05449 PSD95pdz3_S371M,PSD95pdz3_371,PSD95pdz3,PSD95pdz3,P31016,1.05449,NO,371,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.86,-4.257,2.397,5.19744,,,,,17.1117,3.854,,87.71,HPB,-1.598,0.0758425,0.000847873,1.05449 kka2_1:8_K138D,kka2_1:8_138,Kka2,kka2_1:8,P00552,1.0545,NO,138,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-2.5,-2.178,-0.322,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.100394,0.00628542,1.0545 kka2_1:8_K138D,kka2_1:8_138,Kka2,kka2_1:8,P00552,1.0545,NO,138,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-2.5,-2.178,-0.322,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.100394,0.00628542,1.0545 PSD95pdz3_R354I,PSD95pdz3_354,PSD95pdz3,PSD95pdz3,P31016,1.05457,NO,354,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.582,-3.692,2.11,6.21887,,,,,23.7791,,,,HBB,-1.44833,0.0758425,0.000650924,1.05457 PSD95pdz3_K355V,PSD95pdz3_355,PSD95pdz3,PSD95pdz3,P31016,1.05459,NO,355,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.416,-3.21,1.794,5.56865,,,,,17.2556,,,,BBO,-1.33533,0.0758425,0.00063703,1.05459 gb1_D273M,gb1_273,gb1,gb1,P06654,1.0546,NO,273,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.998,-4.599,2.601,,,,,,,3.514,3.514,37.28,AAH,-1.72767,0.177985,0.00318903,1.0546 kka2_1:1_Q163L,kka2_1:1_163,Kka2,kka2_1:1,P00552,1.0546,NO,163,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.162,-1.74,-0.422,,0.58,T,B,0.64,1.85,2.779,,64.02,BPO,-1.78333,0.520039,0.00719507,1.0546 kka2_1:8_R253T,kka2_1:8_253,Kka2,kka2_1:8,P00552,1.05462,NO,253,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.356,-3.535,2.179,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.100394,0.0144195,1.05462 kka2_1:8_R253T,kka2_1:8_253,Kka2,kka2_1:8,P00552,1.05462,NO,253,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.356,-3.535,2.179,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.100394,0.0144195,1.05462 kka2_1:4_H139P,kka2_1:4_139,Kka2,kka2_1:4,P00552,1.05469,NO,139,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-2.809,-4.177,1.368,,0.471,H,A,0.17,0.68,12.761,12.761,63.64,BBB,-2.22,0.168804,0.00734779,1.05469 gb1_T251C,gb1_251,gb1,gb1,P06654,1.05472,NO,251,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.794,-4.706,2.912,,,,,,,3.514,3.514,37.28,HPH,-1.56067,0.177985,0.00232932,1.05472 kka2_1:8_A35C,kka2_1:8_35,Kka2,kka2_1:8,P00552,1.0548,NO,35,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.127,-3.602,1.475,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.100394,0.00630016,1.0548 kka2_1:8_A35C,kka2_1:8_35,Kka2,kka2_1:8,P00552,1.0548,NO,35,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.127,-3.602,1.475,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.100394,0.00630016,1.0548 beta-lactamase_L196K,beta-lactamase_196,TEM-1,beta-lactamase,P62593,1.05481,NO,196,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-2.478,-3.633,1.155,,0.518,S,A,0.55,1.35,,,77.62,AHH,-1.839,0.221079,0.00512144,1.05481 beta-lactamase_L19K,beta-lactamase_19,TEM-1,beta-lactamase,P62593,1.05481,NO,19,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.682,-3.606,1.924,,,,,,,4.261,,93.01,OHO,-1.894,0.221079,0.00215974,1.05481 beta-lactamase_Q274T,beta-lactamase_274,TEM-1,beta-lactamase,P62593,1.05481,NO,274,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.082,-3.431,1.349,5.6671,0.066,H,A,0.11,-0.27,2.354,,64.69,BPH,-1.931,0.221079,0.0110418,1.05481 beta-lactamase_0_G234W,beta-lactamase_0_234,TEM-1,beta-lactamase_0,P62593,1.05485,NO,234,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.62,-5.097,4.477,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.0500837,0.000889577,1.05485 kka2_1:4_A65Q,kka2_1:4_65,Kka2,kka2_1:4,P00552,1.05485,NO,65,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.744,-2.822,1.078,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.168804,0.00709258,1.05485 WW_domain_S184G,WW_domain_184,Yap65,WW_domain,P46937,1.05485,NO,184,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.363,-2.858,1.495,5.06696,,,,,,,,,PPO,-1.39133,0.153962,0.00231095,1.05485 PSD95pdz3_G322A,PSD95pdz3_322,PSD95pdz3,PSD95pdz3,P31016,1.05486,NO,322,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.008,-2.534,1.526,5.24791,,,,,16.3275,,,,POH,-1.24867,0.0758425,0.00105821,1.05486 beta-lactamase_0_E145S,beta-lactamase_0_145,TEM-1,beta-lactamase_0,P62593,1.05487,NO,145,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.357,-2.669,0.312,,0.545,H,A,1.04,0.79,1.199,,77.62,BAH,-2.069,0.0500837,0.00553285,1.05487 beta-lactamase_0_G281H,beta-lactamase_0_281,TEM-1,beta-lactamase_0,P62593,1.05489,NO,281,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.0500837,0.0406482,1.05489 Pab1_G188R,Pab1_188,Pab1,Pab1,P04147,1.0549,NO,188,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.809,-3.75,2.941,,0.379,E,g,,2.18,,,,POH,-1.14633,0.175299,0.000280911,1.0549 kka2_1:4_C192S,kka2_1:4_192,Kka2,kka2_1:4,P00552,1.05491,NO,192,C,S,CS,Special,Polar,5.07,5.68,0.61,112,121,105,-16,108.5,89,-19.5,-1.067,-2.445,1.378,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.168804,0.00485428,1.05491 kka2_1:4_S105L,kka2_1:4_105,Kka2,kka2_1:4,P00552,1.05491,NO,105,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.945,-2.961,1.016,,0.056,S,B,0.77,-1.04,3.442,,65.53,PPB,-2.17033,0.168804,0.00847233,1.05491 PSD95pdz3_S361V,PSD95pdz3_361,PSD95pdz3,PSD95pdz3,P31016,1.05492,NO,361,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.519,-3.21,1.691,4.8722,,,,,16.4533,,,,HPH,-1.47167,0.0758425,0.00055296,1.05492 kka2_1:8_L193M,kka2_1:8_193,Kka2,kka2_1:8,P00552,1.05494,NO,193,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.983,-2.486,1.503,,,G,A,1.59,-1.03,2.234,,65.53,OHO,-0.965333,0.100394,0.00480179,1.05494 kka2_1:8_L193M,kka2_1:8_193,Kka2,kka2_1:8,P00552,1.05494,NO,193,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.983,-2.486,1.503,,,G,A,1.59,-1.03,2.234,,65.53,OHO,-0.965333,0.100394,0.00480179,1.05494 beta-lactamase_0_M180W,beta-lactamase_0_180,TEM-1,beta-lactamase_0,P62593,1.05495,NO,180,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-2.795,-5.124,2.329,,0.242,,B,0.55,-0.94,2.892,,77.62,PHO,-1.56433,0.0500837,0.00552048,1.05495 beta-lactamase_0_Q267C,beta-lactamase_0_267,TEM-1,beta-lactamase_0,P62593,1.05498,NO,267,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.0500837,0.0102128,1.05498 beta-lactamase_625_V106M,beta-lactamase_625_106,TEM-1,beta-lactamase_625,P62593,1.05499,NO,106,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.218,-3.026,1.808,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.213352,0.00304168,1.05499 beta-lactamase_0_E56K,beta-lactamase_0_56,TEM-1,beta-lactamase_0,P62593,1.05503,NO,56,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.043,-3.327,1.284,,0.198,E,B,1.04,0.31,1.491,,72.73,HAP,-1.94033,0.0500837,0.00238534,1.05503 beta-lactamase_39_T193K,beta-lactamase_39_193,TEM-1,beta-lactamase_39,P62593,1.05507,NO,193,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.914,-3.726,1.812,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.0495842,0.00482669,1.05507 beta-lactamase_39_R92K,beta-lactamase_39_92,TEM-1,beta-lactamase_39,P62593,1.05508,NO,92,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.718,-2.258,0.54,,0.479,E,B,1.2,1.36,0.389,,65.38,BBH,-1.50367,0.0495842,0.00429626,1.05508 kka2_1:8_C31S,kka2_1:8_31,Kka2,kka2_1:8,P00552,1.0551,NO,31,C,S,CS,Special,Polar,5.07,5.68,0.61,112,121,105,-16,108.5,89,-19.5,-2.246,-3.485,1.239,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.100394,0.00681582,1.0551 kka2_1:8_C31S,kka2_1:8_31,Kka2,kka2_1:8,P00552,1.0551,NO,31,C,S,CS,Special,Polar,5.07,5.68,0.61,112,121,105,-16,108.5,89,-19.5,-2.246,-3.485,1.239,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.100394,0.00681582,1.0551 beta-lactamase_39_P60I,beta-lactamase_39_60,TEM-1,beta-lactamase_39,P62593,1.05512,NO,60,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-2.469,-3.895,1.426,,0.256,T,A,0.52,-0.56,21.37,21.37,77.62,BOA,-1.97633,0.0495842,0.00521318,1.05512 kka2_1:8_Y22W,kka2_1:8_22,Kka2,kka2_1:8,P00552,1.05516,NO,22,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-1.583,-4.944,3.361,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.100394,0.00598977,1.05516 kka2_1:8_Y22W,kka2_1:8_22,Kka2,kka2_1:8,P00552,1.05516,NO,22,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-1.583,-4.944,3.361,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.100394,0.00598977,1.05516 kka2_1:4_E230K,kka2_1:4_230,Kka2,kka2_1:4,P00552,1.05517,NO,230,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.672,-3.648,0.976,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.168804,0.00920051,1.05517 beta-lactamase_39_F149G,beta-lactamase_39_149,TEM-1,beta-lactamase_39,P62593,1.05518,NO,149,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.299,-3.587,2.288,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.0495842,0.00418462,1.05518 beta-lactamase_V29N,beta-lactamase_29,TEM-1,beta-lactamase,P62593,1.05518,NO,29,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-2.856,-2.832,-0.024,5.58481,0.733,H,A,0.23,-0.78,1.287,,93.01,HHB,-2.24733,0.221079,0.00318969,1.05518 PSD95pdz3_V365M,PSD95pdz3_365,PSD95pdz3,PSD95pdz3,P31016,1.05521,NO,365,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.592,-3.963,2.371,5.03791,,,,,18.9657,2.364,,81.35,OHA,-1.288,0.0758425,0.000649764,1.05521 beta-lactamase_0_Q37K,beta-lactamase_0_37,TEM-1,beta-lactamase_0,P62593,1.05523,NO,37,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.134,-2.595,0.461,,0.613,H,A,0.64,1.98,4.001,,73.08,APH,-2.06967,0.0500837,0.00425833,1.05523 kka2_1:8_G151F,kka2_1:8_151,Kka2,kka2_1:8,P00552,1.05523,NO,151,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.873,-4.384,3.511,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.100394,0.00339918,1.05523 kka2_1:8_G151F,kka2_1:8_151,Kka2,kka2_1:8,P00552,1.05523,NO,151,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.873,-4.384,3.511,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.100394,0.00339918,1.05523 beta-lactamase_39_E279Y,beta-lactamase_39_279,TEM-1,beta-lactamase_39,P62593,1.05527,NO,279,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.0495842,0.0192826,1.05527 beta-lactamase_0_A148P,beta-lactamase_0_148,TEM-1,beta-lactamase_0,P62593,1.05528,NO,148,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.757,-3.925,2.168,,0.379,H,A,0.46,-0.55,19.42,19.42,72.73,PHH,-1.40167,0.0500837,0.00547053,1.05528 gb1_D273C,gb1_273,gb1,gb1,P06654,1.05529,NO,273,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.998,-4.863,2.865,,,,,,,3.514,3.514,37.28,AAH,-1.72767,0.177985,0.00318903,1.05529 gb1_E245G,gb1_245,gb1,gb1,P06654,1.05529,NO,245,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.725,-3.094,0.369,,,,,,,0.712,,45.54,PAH,-1.84567,0.177985,0.00158611,1.05529 kka2_1:8_L70C,kka2_1:8_70,Kka2,kka2_1:8,P00552,1.05535,NO,70,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.017,-4.768,3.751,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.100394,0.00411884,1.05535 kka2_1:8_L70C,kka2_1:8_70,Kka2,kka2_1:8,P00552,1.05535,NO,70,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.017,-4.768,3.751,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.100394,0.00411884,1.05535 kka2_1:8_A79S,kka2_1:8_79,Kka2,kka2_1:8,P00552,1.05538,NO,79,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.368,-2.87,0.502,,0.563,.,B,0.46,-0.43,,,71.59,HHH,-1.752,0.100394,0.00664821,1.05538 kka2_1:8_A79S,kka2_1:8_79,Kka2,kka2_1:8,P00552,1.05538,NO,79,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.368,-2.87,0.502,,0.563,.,B,0.46,-0.43,,,71.59,HHH,-1.752,0.100394,0.00664821,1.05538 gb1_I232Y,gb1_232,gb1,gb1,P06654,1.0554,NO,232,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-2.175,-3.96,1.785,,,,,,,0.766,,44.87,HHH,-2.152,0.177985,0.00580459,1.0554 gb1_K239R,gb1_239,gb1,gb1,P06654,1.0554,NO,239,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-3.043,-3.4,0.357,,,,,,,1.326,,45.54,HBO,-2.31467,0.177985,0.00207004,1.0554 beta-lactamase_39_R176C,beta-lactamase_39_176,TEM-1,beta-lactamase_39,P62593,1.05542,NO,176,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-0.863,-5.087,4.224,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.0495842,0.00105554,1.05542 PSD95pdz3_E352L,PSD95pdz3_352,PSD95pdz3,PSD95pdz3,P31016,1.05542,NO,352,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.587,-3.155,1.568,5.49659,,,,,24.2,2.525,,86.88,OAH,-1.314,0.0758425,0.000892231,1.05542 beta-lactamase_39_L223K,beta-lactamase_39_223,TEM-1,beta-lactamase_39,P62593,1.05547,NO,223,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.055,-3.742,2.687,,0.27,,B,0.55,0.09,1.511,,74.48,HHO,-1.35033,0.0495842,0.00372793,1.05547 beta-lactamase_0_I261H,beta-lactamase_0_261,TEM-1,beta-lactamase_0,P62593,1.05549,NO,261,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.0500837,0.0123091,1.05549 beta-lactamase_39_A282F,beta-lactamase_39_282,TEM-1,beta-lactamase_39,P62593,1.05551,NO,282,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.0495842,0.0449821,1.05551 kka2_1:2_R143N,kka2_1:2_143,Kka2,kka2_1:2,P00552,1.05553,NO,143,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.525,-3.927,1.402,,0.325,H,A,0.16,1.22,14.853,14.853,65.53,ABH,-1.86833,0.295029,0.00662247,1.05553 beta-lactamase_0_L55I,beta-lactamase_0_55,TEM-1,beta-lactamase_0,P62593,1.05557,NO,55,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.86,-2.434,0.574,,0.372,E,A,0.55,-0.36,1.967,,63.99,HHA,-2.247,0.0500837,0.00403741,1.05557 kka2_1:2_A168E,kka2_1:2_168,Kka2,kka2_1:2,P00552,1.05564,NO,168,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.989,-2.167,0.178,,0.67,H,A,0.46,0.15,25.546,25.546,64.39,OHA,-2.12933,0.295029,0.00806773,1.05564 PSD95pdz3_H317A,PSD95pdz3_317,PSD95pdz3,PSD95pdz3,P31016,1.05567,NO,317,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-1.627,-2.984,1.357,6.19713,,,,,25.885,,,,HBB,-1.613,0.0758425,0.00111619,1.05567 kka2_1:2_Q26K,kka2_1:2_26,Kka2,kka2_1:2,P00552,1.05572,NO,26,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.18,-2.687,0.507,,0.448,E,B,0.4,0.44,5.022,,92.05,HPP,-2.11167,0.295029,0.00708962,1.05572 PSD95pdz3_A378N,PSD95pdz3_378,PSD95pdz3,PSD95pdz3,P31016,1.05572,NO,378,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.307,-3.58,2.273,4.86582,,,,,14.576,,,,HHH,-1.509,0.0758425,0.000313169,1.05572 PSD95pdz3_L349I,PSD95pdz3_349,PSD95pdz3,PSD95pdz3,P31016,1.05575,NO,349,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.347,-2.567,1.22,5.14696,,,,,24.6438,,,,AHP,-1.37667,0.0758425,0.00071841,1.05575 beta-lactamase_625_V106E,beta-lactamase_625_106,TEM-1,beta-lactamase_625,P62593,1.05577,NO,106,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.218,-3.859,2.641,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.213352,0.00304168,1.05577 kka2_1:2_M178I,kka2_1:2_178,Kka2,kka2_1:2,P00552,1.05577,NO,178,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-3.206,-2.948,-0.258,,0.554,.,b,0.55,0.68,3.152,,71.59,BHO,-2.154,0.295029,0.00717253,1.05577 beta-lactamase_0_E108T,beta-lactamase_0_108,TEM-1,beta-lactamase_0,P62593,1.05578,NO,108,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.46,-3.526,2.066,,0.572,G,A,1.04,1.87,8.602,8.602,72.73,PAB,-1.437,0.0500837,0.00413372,1.05578 PSD95pdz3_R313Q,PSD95pdz3_313,PSD95pdz3,PSD95pdz3,P31016,1.05578,NO,313,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.582,-3.131,1.549,6.63563,,,,,18.3955,,,,BBH,-1.59733,0.0758425,0.000840067,1.05578 beta-lactamase_0_L73C,beta-lactamase_0_73,TEM-1,beta-lactamase_0,P62593,1.05585,NO,73,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.507,-4.861,3.354,,,H,A,0.55,-0.64,0.877,,67.83,HHH,-1.487,0.0500837,0.00488983,1.05585 kka2_1:8_R202G,kka2_1:8_202,Kka2,kka2_1:8,P00552,1.05585,NO,202,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.761,-2.403,0.642,,0.607,E,B,1.2,0.48,1.409,,52.27,OBH,-1.41067,0.100394,0.00696498,1.05585 kka2_1:8_R202G,kka2_1:8_202,Kka2,kka2_1:8,P00552,1.05585,NO,202,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.761,-2.403,0.642,,0.607,E,B,1.2,0.48,1.409,,52.27,OBH,-1.41067,0.100394,0.00696498,1.05585 beta-lactamase_39_E87C,beta-lactamase_39_87,TEM-1,beta-lactamase_39,P62593,1.05587,NO,87,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.421,-5.162,3.741,,0.048,,B,1.04,0.92,15.231,15.231,64.69,PAP,-1.969,0.0495842,0.00337888,1.05587 beta-lactamase_0_E279G,beta-lactamase_0_279,TEM-1,beta-lactamase_0,P62593,1.05589,NO,279,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.038,-3.588,2.55,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.0500837,0.0192826,1.05589 beta-lactamase_0_G281P,beta-lactamase_0_281,TEM-1,beta-lactamase_0,P62593,1.05592,NO,281,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.0500837,0.0406482,1.05592 beta-lactamase_0_L79T,beta-lactamase_0_79,TEM-1,beta-lactamase_0,P62593,1.05596,NO,79,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.842,-3.447,2.605,,0.007,H,A,0.55,-0.16,5.053,,50.35,HHP,-1.44333,0.0500837,0.000947397,1.05596 beta-lactamase_0_I54F,beta-lactamase_0_54,TEM-1,beta-lactamase_0,P62593,1.05599,NO,54,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-2.838,-4.242,1.404,,0.669,E,B,0.48,-0.14,0.541,,73.78,BHH,-2.337,0.0500837,0.00403589,1.05599 beta-lactamase_625_V106N,beta-lactamase_625_106,TEM-1,beta-lactamase_625,P62593,1.05601,NO,106,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.218,-4.217,2.999,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.213352,0.00304168,1.05601 beta-lactamase_39_I171C,beta-lactamase_39_171,TEM-1,beta-lactamase_39,P62593,1.05602,NO,171,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-2.431,-4.938,2.507,,0.361,,B,0.48,0.53,16.954,16.954,77.62,HHO,-1.55533,0.0495842,0.00623355,1.05602 kka2_1:4_A71W,kka2_1:4_71,Kka2,kka2_1:4,P00552,1.05602,NO,71,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.824,-5.529,3.705,,0.553,H,A,0.46,0.08,5.76,,64.39,HHP,-1.74033,0.168804,0.00727707,1.05602 kka2_1:8_A110T,kka2_1:8_110,Kka2,kka2_1:8,P00552,1.05602,NO,110,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.064,-3.141,1.077,,0.175,H,A,1.04,-1.19,11.413,11.413,71.59,OHA,-1.91867,0.100394,0.00759851,1.05602 kka2_1:8_A110T,kka2_1:8_110,Kka2,kka2_1:8,P00552,1.05602,NO,110,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.064,-3.141,1.077,,0.175,H,A,1.04,-1.19,11.413,11.413,71.59,OHA,-1.91867,0.100394,0.00759851,1.05602 beta-lactamase_0_P60E,beta-lactamase_0_60,TEM-1,beta-lactamase_0,P62593,1.05604,NO,60,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-2.469,-2.856,0.387,,0.256,T,A,0.52,-0.56,3.653,,77.62,BOA,-1.97633,0.0500837,0.00521318,1.05604 beta-lactamase_0_T264Q,beta-lactamase_0_264,TEM-1,beta-lactamase_0,P62593,1.05605,NO,264,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.0500837,0.0119399,1.05605 beta-lactamase_39_F149E,beta-lactamase_39_149,TEM-1,beta-lactamase_39,P62593,1.05607,NO,149,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.299,-3.842,2.543,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.0495842,0.00418462,1.05607 gb1_T251H,gb1_251,gb1,gb1,P06654,1.05608,NO,251,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.794,-4.395,2.601,,,,,,,3.514,3.514,37.28,HPH,-1.56067,0.177985,0.00232932,1.05608 beta-lactamase_0_L219H,beta-lactamase_0_219,TEM-1,beta-lactamase_0,P62593,1.05609,NO,219,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.313,-4.957,3.644,,,I,A,0.55,-0.51,6.513,6.513,74.48,HHB,-1.21533,0.0500837,0.00664345,1.05609 beta-lactamase_39_L223I,beta-lactamase_39_223,TEM-1,beta-lactamase_39,P62593,1.05611,NO,223,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.055,-2.996,1.941,,0.27,,B,0.55,0.09,1.511,,74.48,HHO,-1.35033,0.0495842,0.00372793,1.05611 kka2_1:8_E96R,kka2_1:8_96,Kka2,kka2_1:8,P00552,1.05624,NO,96,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.573,-2.69,0.117,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.100394,0.00369441,1.05624 kka2_1:8_E96R,kka2_1:8_96,Kka2,kka2_1:8,P00552,1.05624,NO,96,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.573,-2.69,0.117,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.100394,0.00369441,1.05624 kka2_1:8_H139Y,kka2_1:8_139,Kka2,kka2_1:8,P00552,1.05624,NO,139,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-2.809,-3.482,0.673,,0.471,H,A,0.17,0.68,28.583,28.583,63.64,BBB,-2.22,0.100394,0.00734779,1.05624 kka2_1:8_H139Y,kka2_1:8_139,Kka2,kka2_1:8,P00552,1.05624,NO,139,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-2.809,-3.482,0.673,,0.471,H,A,0.17,0.68,28.583,28.583,63.64,BBB,-2.22,0.100394,0.00734779,1.05624 beta-lactamase_0_A278G,beta-lactamase_0_278,TEM-1,beta-lactamase_0,P62593,1.05626,NO,278,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.348,,,,0.015,H,A,0.48,-0.85,4.624,,63.29,HHA,-1.41833,0.0500837,0.0310297,1.05626 gb1_D248Y,gb1_248,gb1,gb1,P06654,1.05631,NO,248,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.569,-4.08,2.511,,,,,,,0.344,,11.83,HAH,-1.673,0.177985,0.001865,1.05631 gb1_I232L,gb1_232,gb1,gb1,P06654,1.05631,NO,232,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-2.175,-2.763,0.588,,,,,,,0.766,,44.87,HHH,-2.152,0.177985,0.00580459,1.05631 beta-lactamase_39_V106F,beta-lactamase_39_106,TEM-1,beta-lactamase_39,P62593,1.05635,NO,106,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.218,-2.585,1.367,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.0495842,0.00304168,1.05635 kka2_1:8_A78T,kka2_1:8_78,Kka2,kka2_1:8,P00552,1.05636,NO,78,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.744,-3.425,1.681,,0.078,,B,1.04,-0.53,1.251,,56.06,OHH,-1.863,0.100394,0.00457299,1.05636 kka2_1:8_A78T,kka2_1:8_78,Kka2,kka2_1:8,P00552,1.05636,NO,78,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.744,-3.425,1.681,,0.078,,B,1.04,-0.53,1.251,,56.06,OHH,-1.863,0.100394,0.00457299,1.05636 beta-lactamase_0_E46H,beta-lactamase_0_46,TEM-1,beta-lactamase_0,P62593,1.0564,NO,46,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.94,-4.828,2.888,,0.021,E,B,1.04,0.14,30.306,30.306,59.44,HAH,-2.079,0.0500837,0.00427568,1.0564 gb1_D248F,gb1_248,gb1,gb1,P06654,1.05642,NO,248,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.569,-3.984,2.415,,,,,,,0.344,,11.83,HAH,-1.673,0.177985,0.001865,1.05642 gb1_D266R,gb1_266,gb1,gb1,P06654,1.05642,NO,266,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.261,-3.773,2.512,,,,,,,0.638,,45.54,HAO,-1.59333,0.177985,0.00394694,1.05642 gb1_N234R,gb1_234,gb1,gb1,P06654,1.05642,NO,234,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-2.055,-2.068,0.013,,,,,,,1.235,,45.54,HPO,-2.05067,0.177985,0.00242189,1.05642 PSD95pdz3_V315I,PSD95pdz3_315,PSD95pdz3,PSD95pdz3,P31016,1.05648,NO,315,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.625,-1.941,0.316,5.52024,,,,,18.4557,4.054,,81.35,HHH,-1.62767,0.0758425,0.00153536,1.05648 kka2_1:2_D156F,kka2_1:2_156,Kka2,kka2_1:2,P00552,1.05652,NO,156,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.696,-4.395,2.699,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.295029,0.00926998,1.05652 gb1_D248H,gb1_248,gb1,gb1,P06654,1.05654,NO,248,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.569,-4.266,2.697,,,,,,,0.344,,11.83,HAH,-1.673,0.177985,0.001865,1.05654 beta-lactamase_156_R159F,beta-lactamase_156_159,TEM-1,beta-lactamase_156,P62593,1.05664,NO,159,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-0.94,-4.255,3.315,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.111618,0.00108472,1.05664 PSD95pdz3_Q358C,PSD95pdz3_358,PSD95pdz3,PSD95pdz3,P31016,1.05664,NO,358,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-1.699,-4.769,3.07,5.21282,,,,,14.8844,,,,APH,-1.531,0.0758425,0.000594893,1.05664 beta-lactamase_0_A84D,beta-lactamase_0_84,TEM-1,beta-lactamase_0,P62593,1.05666,NO,84,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.651,-2.92,1.269,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.0500837,0.00503822,1.05666 PSD95pdz3_N326C,PSD95pdz3_326,PSD95pdz3,PSD95pdz3,P31016,1.05668,NO,326,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-1.41,-4.769,3.359,5.52537,,,,,19.0688,,,,HPH,-1.52133,0.0758425,0.00101078,1.05668 beta-lactamase_0_G240H,beta-lactamase_0_240,TEM-1,beta-lactamase_0,P62593,1.05669,NO,240,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.0500837,0.00591201,1.05669 beta-lactamase_0_I277R,beta-lactamase_0_277,TEM-1,beta-lactamase_0,P62593,1.05674,NO,277,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.0500837,0.0169305,1.05674 beta-lactamase_39_W208F,beta-lactamase_39_208,TEM-1,beta-lactamase_39,P62593,1.05679,NO,208,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-0.818,-3.392,2.574,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.0495842,0.00126609,1.05679 kka2_1:2_A229E,kka2_1:2_229,Kka2,kka2_1:2,P00552,1.05685,NO,229,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.739,-2.079,0.34,,0.32,H,A,0.46,-0.7,6.549,,63.64,HHA,-1.851,0.295029,0.00942138,1.05685 beta-lactamase_0_G236C,beta-lactamase_0_236,TEM-1,beta-lactamase_0,P62593,1.05686,NO,236,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.784,-4.991,4.207,,0.241,,b,0.29,-0.59,3.506,,64.69,HOO,-1.025,0.0500837,0.00162372,1.05686 gb1_Q228P,gb1_228,gb1,gb1,P06654,1.05688,NO,228,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,,,,,,,,,,,,,OPH,-1.282,0.177985,0.00391043,1.05688 kka2_1:8_C77H,kka2_1:8_77,Kka2,kka2_1:8,P00552,1.05689,NO,77,C,H,CH,Special,PositiveCharge,5.07,7.59,2.52,174,121,155,34,108.5,153.2,44.7,-1.477,-4.937,3.46,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.100394,0.00441216,1.05689 kka2_1:8_C77H,kka2_1:8_77,Kka2,kka2_1:8,P00552,1.05689,NO,77,C,H,CH,Special,PositiveCharge,5.07,7.59,2.52,174,121,155,34,108.5,153.2,44.7,-1.477,-4.937,3.46,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.100394,0.00441216,1.05689 kka2_1:8_E86G,kka2_1:8_86,Kka2,kka2_1:8,P00552,1.05691,NO,86,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.86,-2.302,0.442,,0.369,,B,1.52,1.92,,,63.26,PAH,-1.98067,0.100394,0.00642858,1.05691 kka2_1:8_E86G,kka2_1:8_86,Kka2,kka2_1:8,P00552,1.05691,NO,86,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.86,-2.302,0.442,,0.369,,B,1.52,1.92,,,63.26,PAH,-1.98067,0.100394,0.00642858,1.05691 beta-lactamase_0_R92G,beta-lactamase_0_92,TEM-1,beta-lactamase_0,P62593,1.05695,NO,92,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.718,-3.552,1.834,,0.479,E,B,1.2,1.36,2.331,,65.38,BBH,-1.50367,0.0500837,0.00429626,1.05695 beta-lactamase_0_D271N,beta-lactamase_0_271,TEM-1,beta-lactamase_0,P62593,1.05697,NO,271,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.0500837,0.00752082,1.05697 kka2_1:8_Q136T,kka2_1:8_136,Kka2,kka2_1:8,P00552,1.05697,NO,136,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-3.021,-2.627,-0.394,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.100394,0.00624149,1.05697 kka2_1:8_Q136T,kka2_1:8_136,Kka2,kka2_1:8,P00552,1.05697,NO,136,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-3.021,-2.627,-0.394,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.100394,0.00624149,1.05697 WW_domain_E178D,WW_domain_178,Yap65,WW_domain,P46937,1.05699,NO,178,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.158,-2.571,1.413,5.22323,,,,,,,,,HAH,-1.299,0.153962,0.0016738,1.05699 kka2_1:4_L152H,kka2_1:4_152,Kka2,kka2_1:4,P00552,1.05704,NO,152,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.521,-4.868,3.347,,0.547,,A,1.59,1.36,2.318,,63.64,OHH,-1.162,0.168804,0.00674868,1.05704 beta-lactamase_0_I261A,beta-lactamase_0_261,TEM-1,beta-lactamase_0,P62593,1.0571,NO,261,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.0500837,0.0123091,1.0571 kka2_1:8_P179R,kka2_1:8_179,Kka2,kka2_1:8,P00552,1.0571,NO,179,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.974,-4.006,3.032,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.100394,0.00298346,1.0571 kka2_1:8_P179R,kka2_1:8_179,Kka2,kka2_1:8,P00552,1.0571,NO,179,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.974,-4.006,3.032,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.100394,0.00298346,1.0571 kka2_1:8_A166G,kka2_1:8_166,Kka2,kka2_1:8,P00552,1.05711,NO,166,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.407,-2.83,0.423,,0.534,,B,1.04,1.03,13.995,13.995,71.59,HHO,-2.421,0.100394,0.00799912,1.05711 kka2_1:8_A166G,kka2_1:8_166,Kka2,kka2_1:8,P00552,1.05711,NO,166,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.407,-2.83,0.423,,0.534,,B,1.04,1.03,13.995,13.995,71.59,HHO,-2.421,0.100394,0.00799912,1.05711 kka2_1:4_S68F,kka2_1:4_68,Kka2,kka2_1:4,P00552,1.05713,NO,68,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.623,-4.425,1.802,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.168804,0.00608265,1.05713 kka2_1:2_A150R,kka2_1:2_150,Kka2,kka2_1:2,P00552,1.05716,NO,150,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.949,-3.769,2.82,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.295029,0.0045009,1.05716 kka2_1:2_A168W,kka2_1:2_168,Kka2,kka2_1:2,P00552,1.05716,NO,168,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.989,-5.548,3.559,,0.67,H,A,0.46,0.15,25.546,25.546,64.39,OHA,-2.12933,0.295029,0.00806773,1.05716 kka2_1:2_A65C,kka2_1:2_65,Kka2,kka2_1:2,P00552,1.05718,NO,65,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.744,-5.062,3.318,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.295029,0.00709258,1.05718 PSD95pdz3_Q391H,PSD95pdz3_391,PSD95pdz3,PSD95pdz3,P31016,1.05718,NO,391,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-1.699,-3.912,2.213,5.50275,,,,,12.6589,,,,HPH,-1.481,0.0758425,0.000990786,1.05718 beta-lactamase_39_S201L,beta-lactamase_39_201,TEM-1,beta-lactamase_39,P62593,1.0572,NO,201,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.183,-2.615,1.432,,0.064,H,A,0.27,-0.07,3.54,,64.69,HPB,-1.451,0.0495842,0.00198815,1.0572 gb1_D262M,gb1_262,gb1,gb1,P06654,1.05722,NO,262,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-3.132,-4.451,1.319,,,,,,,1.304,,45.54,PAP,-2.05233,0.177985,0.00413102,1.05722 kka2_1:8_K175R,kka2_1:8_175,Kka2,kka2_1:8,P00552,1.05725,NO,175,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-2.897,-2.852,-0.045,,0.579,H,A,2.34,0.51,15.316,15.316,71.59,HBH,-1.82333,0.100394,0.00693093,1.05725 kka2_1:8_K175R,kka2_1:8_175,Kka2,kka2_1:8,P00552,1.05725,NO,175,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-2.897,-2.852,-0.045,,0.579,H,A,2.34,0.51,15.316,15.316,71.59,HBH,-1.82333,0.100394,0.00693093,1.05725 kka2_1:8_V97A,kka2_1:8_97,Kka2,kka2_1:8,P00552,1.05725,NO,97,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.453,-2.616,1.163,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.100394,0.00737869,1.05725 kka2_1:8_V97A,kka2_1:8_97,Kka2,kka2_1:8,P00552,1.05725,NO,97,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.453,-2.616,1.163,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.100394,0.00737869,1.05725 kka2_1:2_Q61L,kka2_1:2_61,Kka2,kka2_1:2,P00552,1.05729,NO,61,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.982,-2.984,0.002,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.295029,0.00612092,1.05729 kka2_1:2_Q61W,kka2_1:2_61,Kka2,kka2_1:2,P00552,1.05735,NO,61,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.982,-5.59,2.608,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.295029,0.00612092,1.05735 beta-lactamase_39_I93K,beta-lactamase_39_93,TEM-1,beta-lactamase_39,P62593,1.0574,NO,93,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.401,-3.873,2.472,,0.128,E,B,0.48,0.44,1.757,,67.83,BHB,-1.873,0.0495842,0.00527066,1.0574 kka2_1:4_P12A,kka2_1:4_12,Kka2,kka2_1:4,P00552,1.05742,NO,12,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.853,-2.153,1.3,,,,B,0.52,1.25,0.843,,48.11,POH,-1.80767,0.168804,0.00500011,1.05742 kka2_1:4_A71T,kka2_1:4_71,Kka2,kka2_1:4,P00552,1.05745,NO,71,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.824,-2.666,0.842,,0.553,H,A,0.46,0.08,5.76,,64.39,HHP,-1.74033,0.168804,0.00727707,1.05745 beta-lactamase_2500_E210M,beta-lactamase_2500_210,TEM-1,beta-lactamase_2500,P62593,1.05747,NO,210,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.319,-4.371,2.052,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.361275,0.00663582,1.05747 beta-lactamase_0_S283I,beta-lactamase_0_283,TEM-1,beta-lactamase_0,P62593,1.05755,NO,283,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.638,-3.539,1.901,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.0500837,0.0429138,1.05755 gb1_E241R,gb1_241,gb1,gb1,P06654,1.05755,NO,241,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.672,-3.4,1.728,,,,,,,0.344,,11.83,OAP,-1.27933,0.177985,0.00250604,1.05755 kka2_1:8_L57D,kka2_1:8_57,Kka2,kka2_1:8,P00552,1.05756,NO,57,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.898,-4.048,2.15,,0.343,T,A,0.55,0.98,13.359,13.359,52.65,HHP,-2.20733,0.100394,0.00723769,1.05756 kka2_1:8_L57D,kka2_1:8_57,Kka2,kka2_1:8,P00552,1.05756,NO,57,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.898,-4.048,2.15,,0.343,T,A,0.55,0.98,13.359,13.359,52.65,HHP,-2.20733,0.100394,0.00723769,1.05756 beta-lactamase_0_P172M,beta-lactamase_0_172,TEM-1,beta-lactamase_0,P62593,1.0576,NO,172,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.998,-4.616,3.618,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.0500837,0.00312594,1.0576 kka2_1:2_Q26L,kka2_1:2_26,Kka2,kka2_1:2,P00552,1.05761,NO,26,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.18,-2.769,0.589,,0.448,E,B,0.4,0.44,5.022,,92.05,HPP,-2.11167,0.295029,0.00708962,1.05761 beta-lactamase_0_A40Y,beta-lactamase_0_40,TEM-1,beta-lactamase_0,P62593,1.05762,NO,40,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.402,-4.322,2.92,,0.155,S,B,0.46,0.21,0.783,,73.78,OHB,-1.40267,0.0500837,0.00490026,1.05762 kka2_1:4_E169Q,kka2_1:4_169,Kka2,kka2_1:4,P00552,1.05764,NO,169,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.996,-2.511,0.515,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.168804,0.00730086,1.05764 kka2_1:4_R239T,kka2_1:4_239,Kka2,kka2_1:4,P00552,1.05765,NO,239,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.949,-3.616,0.667,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.168804,0.00835326,1.05765 PSD95pdz3_V328M,PSD95pdz3_328,PSD95pdz3,PSD95pdz3,P31016,1.05765,NO,328,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.465,-3.712,2.247,5.28275,,,,,16.8775,,,,HHO,-1.36767,0.0758425,0.000986706,1.05765 beta-lactamase_0_E102H,beta-lactamase_0_102,TEM-1,beta-lactamase_0,P62593,1.05769,NO,102,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.118,-3.309,1.191,,0.722,S,B,1.04,1.82,4.773,,73.08,HAH,-1.581,0.0500837,0.00486633,1.05769 kka2_1:2_A172G,kka2_1:2_172,Kka2,kka2_1:2,P00552,1.05771,NO,172,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.757,-2.418,0.661,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.295029,0.0079265,1.05771 kka2_1:8_V49C,kka2_1:8_49,Kka2,kka2_1:8,P00552,1.05772,NO,49,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.614,-4.784,3.17,,,E,B,1.48,-0.77,1.31,,64.39,HHB,-1.3,0.100394,0.00615685,1.05772 kka2_1:8_V49C,kka2_1:8_49,Kka2,kka2_1:8,P00552,1.05772,NO,49,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.614,-4.784,3.17,,,E,B,1.48,-0.77,1.31,,64.39,HHB,-1.3,0.100394,0.00615685,1.05772 kka2_1:4_R44W,kka2_1:4_44,Kka2,kka2_1:4,P00552,1.05776,NO,44,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.062,-5.515,3.453,,0.487,S,B,1.2,-0.35,5.71,,71.59,OBO,-1.80767,0.168804,0.00745043,1.05776 gb1_T275I,gb1_275,gb1,gb1,P06654,1.05778,NO,275,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.727,-3.435,1.708,,,,,,,0.511,,35.71,HPB,-1.637,0.177985,0.00606618,1.05778 WW_domain_D194G,WW_domain_194,Yap65,WW_domain,P46937,1.05778,NO,194,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.536,-3.173,1.637,5.95614,,,,,,1.948,,74.4,HAP,-1.78933,0.153962,0.00483742,1.05778 beta-lactamase_0_I245E,beta-lactamase_0_245,TEM-1,beta-lactamase_0,P62593,1.05779,NO,245,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.0500837,0.00391032,1.05779 kka2_1:4_L60V,kka2_1:4_60,Kka2,kka2_1:4,P00552,1.0578,NO,60,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.997,-2.277,1.28,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.168804,0.00262176,1.0578 kka2_1:8_A110G,kka2_1:8_110,Kka2,kka2_1:8,P00552,1.0578,NO,110,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.064,-2.863,0.799,,0.175,H,A,1.04,-1.19,11.413,11.413,71.59,OHA,-1.91867,0.100394,0.00759851,1.0578 kka2_1:8_A110G,kka2_1:8_110,Kka2,kka2_1:8,P00552,1.0578,NO,110,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.064,-2.863,0.799,,0.175,H,A,1.04,-1.19,11.413,11.413,71.59,OHA,-1.91867,0.100394,0.00759851,1.0578 kka2_1:4_L165Y,kka2_1:4_165,Kka2,kka2_1:4,P00552,1.05782,NO,165,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-2.453,-4.292,1.839,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.168804,0.00801161,1.05782 kka2_1:8_A191P,kka2_1:8_191,Kka2,kka2_1:8,P00552,1.05783,NO,191,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.831,-2.353,1.522,,,,b,1.04,-0.94,1.306,,50,AHO,-0.868667,0.100394,0.00338807,1.05783 kka2_1:8_A191P,kka2_1:8_191,Kka2,kka2_1:8,P00552,1.05783,NO,191,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.831,-2.353,1.522,,,,b,1.04,-0.94,1.306,,50,AHO,-0.868667,0.100394,0.00338807,1.05783 kka2_1:2_T72M,kka2_1:2_72,Kka2,kka2_1:2,P00552,1.05784,NO,72,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.38,-3.59,1.21,,0.784,H,A,0.82,0.29,6.463,,65.53,HPP,-2.238,0.295029,0.00750756,1.05784 PSD95pdz3_G333F,PSD95pdz3_333,PSD95pdz3,PSD95pdz3,P31016,1.05792,NO,333,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.008,-3.974,2.966,5.09445,,,,,48.755,,,,AOA,-1.22533,0.0758425,0.00092544,1.05792 beta-lactamase_0_S128A,beta-lactamase_0_128,TEM-1,beta-lactamase_0,P62593,1.05793,NO,128,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-0.84,-2.628,1.788,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.0500837,0.00071483,1.05793 kka2_1:4_Q100K,kka2_1:4_100,Kka2,kka2_1:4,P00552,1.05797,NO,100,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.77,-3.068,0.298,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.168804,0.0066405,1.05797 beta-lactamase_39_I171N,beta-lactamase_39_171,TEM-1,beta-lactamase_39,P62593,1.058,NO,171,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-2.431,-3.904,1.473,,0.361,,B,0.48,0.53,16.954,16.954,77.62,HHO,-1.55533,0.0495842,0.00623355,1.058 kka2_1:8_P12W,kka2_1:8_12,Kka2,kka2_1:8,P00552,1.05806,NO,12,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.853,-5.545,4.692,,,.,B,0.52,1.25,2.41,,48.11,POH,-1.80767,0.100394,0.00500011,1.05806 kka2_1:8_P12W,kka2_1:8_12,Kka2,kka2_1:8,P00552,1.05806,NO,12,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.853,-5.545,4.692,,,.,B,0.52,1.25,2.41,,48.11,POH,-1.80767,0.100394,0.00500011,1.05806 PSD95pdz3_A343P,PSD95pdz3_343,PSD95pdz3,PSD95pdz3,P31016,1.05809,NO,343,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.307,-3.336,2.029,5.585,,,,,14.728,,,,HHO,-1.22067,0.0758425,0.000798084,1.05809 PSD95pdz3_R354D,PSD95pdz3_354,PSD95pdz3,PSD95pdz3,P31016,1.05811,NO,354,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.582,-3.375,1.793,6.21887,,,,,23.7791,,,,HBB,-1.44833,0.0758425,0.000650924,1.05811 WW_domain_D170S,WW_domain_170,Yap65,WW_domain,P46937,1.05813,NO,170,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.213,-3.001,1.788,,,,,,,0.399,,15.87,OAH,-1.38,0.153962,0.00123319,1.05813 beta-lactamase_39_P224W,beta-lactamase_39_224,TEM-1,beta-lactamase_39,P62593,1.05814,NO,224,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.893,-5.546,4.653,,0.383,,B,0.52,-0.3,3.169,,74.48,HOH,-1.26433,0.0495842,0.00189564,1.05814 kka2_1:1_A35T,kka2_1:1_35,Kka2,kka2_1:1,P00552,1.05815,NO,35,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.127,-2.654,0.527,,0.107,E,B,0.46,1.05,8.405,8.405,71.59,HHH,-1.31767,0.520039,0.00630016,1.05815 beta-lactamase_0_E279H,beta-lactamase_0_279,TEM-1,beta-lactamase_0,P62593,1.05817,NO,279,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.0500837,0.0192826,1.05817 PSD95pdz3_S320K,PSD95pdz3_320,PSD95pdz3,PSD95pdz3,P31016,1.05821,NO,320,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.519,-2.914,1.395,5.81757,,,,,21.4517,,,,OPP,-1.306,0.0758425,0.00108158,1.05821 PSD95pdz3_G383W,PSD95pdz3_383,PSD95pdz3,PSD95pdz3,P31016,1.05829,NO,383,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.008,-4.779,3.771,5.17213,,,,,20.5325,,,,HOP,-1.338,0.0758425,0.000233044,1.05829 PSD95pdz3_P346A,PSD95pdz3_346,PSD95pdz3,PSD95pdz3,P31016,1.05829,NO,346,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.236,-2.759,1.523,5.02406,,,,,14.6629,,,,OOH,-1.18367,0.0758425,0.000758563,1.05829 gb1_D273I,gb1_273,gb1,gb1,P06654,1.05834,NO,273,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.998,-3.853,1.855,,,,,,,3.514,3.514,37.28,AAH,-1.72767,0.177985,0.00318903,1.05834 beta-lactamase_39_F228A,beta-lactamase_39_228,TEM-1,beta-lactamase_39,P62593,1.05836,NO,228,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-2.342,-2.562,0.22,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.0495842,0.0046669,1.05836 beta-lactamase_0_R91M,beta-lactamase_0_91,TEM-1,beta-lactamase_0,P62593,1.05838,NO,91,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.392,-4.593,3.201,,0.444,,B,1.2,0.96,4.557,,50.35,OBB,-1.73367,0.0500837,0.00380226,1.05838 kka2_1:8_M116V,kka2_1:8_116,Kka2,kka2_1:8,P00552,1.0584,NO,116,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-2.482,-2.282,-0.2,,,H,A,1.59,-0.88,4.659,,71.59,HHH,-1.63867,0.100394,0.00745147,1.0584 kka2_1:8_M116V,kka2_1:8_116,Kka2,kka2_1:8,P00552,1.0584,NO,116,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-2.482,-2.282,-0.2,,,H,A,1.59,-0.88,4.659,,71.59,HHH,-1.63867,0.100394,0.00745147,1.0584 beta-lactamase_625_K190Q,beta-lactamase_625_190,TEM-1,beta-lactamase_625,P62593,1.05841,NO,190,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.994,-2.883,0.889,,0.371,H,A,2.34,0.16,29.753,29.753,77.62,BBH,-1.64167,0.213352,0.00574527,1.05841 gb1_T243R,gb1_243,gb1,gb1,P06654,1.05845,NO,243,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.415,-3.519,2.104,,,,,,,1.083,,37.28,PPP,-1.43233,0.177985,0.00308687,1.05845 gb1_T270Q,gb1_270,gb1,gb1,P06654,1.05845,NO,270,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-3.15,-3.732,0.582,,,,,,,1.326,,45.54,HPH,-1.843,0.177985,0.00223707,1.05845 kka2_1:8_M197L,kka2_1:8_197,Kka2,kka2_1:8,P00552,1.05845,NO,197,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.707,-1.777,0.07,,0.121,E,B,1.59,-1.19,4.408,,65.53,HHH,-1.847,0.100394,0.00921295,1.05845 kka2_1:8_M197L,kka2_1:8_197,Kka2,kka2_1:8,P00552,1.05845,NO,197,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.707,-1.777,0.07,,0.121,E,B,1.59,-1.19,4.408,,65.53,HHH,-1.847,0.100394,0.00921295,1.05845 beta-lactamase_A211D,beta-lactamase_211,TEM-1,beta-lactamase,P62593,1.05853,NO,211,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.896,-1.934,0.038,5.54662,0.369,T,A,0.52,-0.69,2.061,,77.62,AHA,-1.94633,0.221079,0.00648183,1.05853 gb1_D248I,gb1_248,gb1,gb1,P06654,1.05856,NO,248,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.569,-3.702,2.133,,,,,,,0.344,,11.83,HAH,-1.673,0.177985,0.001865,1.05856 beta-lactamase_0_E238V,beta-lactamase_0_238,TEM-1,beta-lactamase_0,P62593,1.05858,NO,238,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.0500837,0.00743256,1.05858 kka2_1:8_A25W,kka2_1:8_25,Kka2,kka2_1:8,P00552,1.05858,NO,25,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.496,-5.529,3.033,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.100394,0.00595636,1.05858 kka2_1:8_A25W,kka2_1:8_25,Kka2,kka2_1:8,P00552,1.05858,NO,25,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.496,-5.529,3.033,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.100394,0.00595636,1.05858 beta-lactamase_39_L197F,beta-lactamase_39_197,TEM-1,beta-lactamase_39,P62593,1.05859,NO,197,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.853,-3.685,2.832,,0.007,S,B,0.55,0.33,1.559,,60.14,HHP,-1.833,0.0495842,0.00144602,1.05859 beta-lactamase_39_I285S,beta-lactamase_39_285,TEM-1,beta-lactamase_39,P62593,1.05862,NO,285,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.0495842,0.101555,1.05862 PSD95pdz3_V365R,PSD95pdz3_365,PSD95pdz3,PSD95pdz3,P31016,1.05862,NO,365,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.592,-3.73,2.138,5.03791,,,,,18.9657,2.364,,81.35,OHA,-1.288,0.0758425,0.000649764,1.05862 kka2_1:4_L170M,kka2_1:4_170,Kka2,kka2_1:4,P00552,1.05865,NO,170,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.28,-3.089,1.809,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.168804,0.00730791,1.05865 beta-lactamase_0_T116S,beta-lactamase_0_116,TEM-1,beta-lactamase_0,P62593,1.05867,NO,116,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.28,-1.932,0.652,,0.115,E,B,0.22,-0.12,1.356,,67.48,HPH,-1.39967,0.0500837,0.00336175,1.05867 PSD95pdz3_L342M,PSD95pdz3_342,PSD95pdz3,PSD95pdz3,P31016,1.05869,NO,342,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.347,-3.487,2.14,5.03015,,,,,12.0762,,,,HHH,-1.428,0.0758425,0.00081112,1.05869 kka2_1:8_P167T,kka2_1:8_167,Kka2,kka2_1:8,P00552,1.05873,NO,167,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-2.403,-2.47,0.067,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.100394,0.00543203,1.05873 kka2_1:8_P167T,kka2_1:8_167,Kka2,kka2_1:8,P00552,1.05873,NO,167,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-2.403,-2.47,0.067,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.100394,0.00543203,1.05873 beta-lactamase_0_A278W,beta-lactamase_0_278,TEM-1,beta-lactamase_0,P62593,1.05874,NO,278,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.348,,,,0.015,H,A,0.48,-0.85,4.624,,63.29,HHA,-1.41833,0.0500837,0.0310297,1.05874 kka2_1:4_G151F,kka2_1:4_151,Kka2,kka2_1:4,P00552,1.05874,NO,151,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.873,-4.384,3.511,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.168804,0.00339918,1.05874 beta-lactamase_0_F58T,beta-lactamase_0_58,TEM-1,beta-lactamase_0,P62593,1.05882,NO,58,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-2.914,-2.91,-0.004,,0.266,E,B,0.58,-0.07,24.637,24.637,77.62,PHB,-2.059,0.0500837,0.00523369,1.05882 beta-lactamase_0_C75L,beta-lactamase_0_75,TEM-1,beta-lactamase_0,P62593,1.05883,NO,75,C,L,CL,Special,Hydrophobic,5.07,9.7088,4.6388,198,121,131,10,108.5,166.7,58.2,-1.245,-3.28,2.035,,,H,A,0.46,-0.87,2.256,,50,HOO,-1.24333,0.0500837,0.0034616,1.05883 kka2_1:8_G164S,kka2_1:8_164,Kka2,kka2_1:8,P00552,1.05884,NO,164,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.869,-2.388,1.519,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.100394,0.00442091,1.05884 kka2_1:8_G164S,kka2_1:8_164,Kka2,kka2_1:8,P00552,1.05884,NO,164,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.869,-2.388,1.519,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.100394,0.00442091,1.05884 beta-lactamase_39_S51F,beta-lactamase_39_51,TEM-1,beta-lactamase_39,P62593,1.05886,NO,51,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.526,-4.284,2.758,,0.496,T,A,0.27,0.26,2.964,,72.73,PPO,-1.88467,0.0495842,0.00504821,1.05886 beta-lactamase_S122M,beta-lactamase_122,TEM-1,beta-lactamase,P62593,1.05888,NO,122,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.406,-4.704,2.298,4.87767,0.352,H,A,0.73,-0.54,1.581,,77.62,OPH,-1.39767,0.221079,0.00497825,1.05888 kka2_1:2_A150H,kka2_1:2_150,Kka2,kka2_1:2,P00552,1.05889,NO,150,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.949,-4.695,3.746,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.295029,0.0045009,1.05889 gb1_D248C,gb1_248,gb1,gb1,P06654,1.0589,NO,248,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.569,-4.648,3.079,,,,,,,0.344,,11.83,HAH,-1.673,0.177985,0.001865,1.0589 beta-lactamase_0_T264D,beta-lactamase_0_264,TEM-1,beta-lactamase_0,P62593,1.05891,NO,264,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.0500837,0.0119399,1.05891 kka2_1:2_R18F,kka2_1:2_18,Kka2,kka2_1:2,P00552,1.05893,NO,18,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.055,-3.418,1.363,,0.474,T,A,1.2,0.54,8.405,8.405,71.59,ABH,-1.821,0.295029,0.00724065,1.05893 beta-lactamase_0_I258P,beta-lactamase_0_258,TEM-1,beta-lactamase_0,P62593,1.05899,NO,258,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.0500837,0.007931,1.05899 beta-lactamase_39_A211V,beta-lactamase_39_211,TEM-1,beta-lactamase_39,P62593,1.05899,NO,211,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.896,-3.651,1.755,,0.369,T,A,0.46,-0.69,1.419,,77.62,AHA,-1.94633,0.0495842,0.00648183,1.05899 kka2_1:8_D52N,kka2_1:8_52,Kka2,kka2_1:8,P00552,1.05904,NO,52,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.271,-3.474,1.203,,0.22,E,B,0.75,0.8,5.447,,71.59,PAH,-2.38367,0.100394,0.00175694,1.05904 kka2_1:8_D52N,kka2_1:8_52,Kka2,kka2_1:8,P00552,1.05904,NO,52,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.271,-3.474,1.203,,0.22,E,B,0.75,0.8,5.447,,71.59,PAH,-2.38367,0.100394,0.00175694,1.05904 beta-lactamase_39_V106T,beta-lactamase_39_106,TEM-1,beta-lactamase_39,P62593,1.05906,NO,106,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.218,-3.428,2.21,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.0495842,0.00304168,1.05906 PSD95pdz3_R354E,PSD95pdz3_354,PSD95pdz3,PSD95pdz3,P31016,1.05909,NO,354,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.582,-2.897,1.315,6.21887,,,,,23.7791,,,,HBB,-1.44833,0.0758425,0.000650924,1.05909 kka2_1:8_E86K,kka2_1:8_86,Kka2,kka2_1:8,P00552,1.05912,NO,86,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.86,-3.566,1.706,,0.369,,B,1.52,1.92,,,63.26,PAH,-1.98067,0.100394,0.00642858,1.05912 kka2_1:8_E86K,kka2_1:8_86,Kka2,kka2_1:8,P00552,1.05912,NO,86,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.86,-3.566,1.706,,0.369,,B,1.52,1.92,,,63.26,PAH,-1.98067,0.100394,0.00642858,1.05912 WW_domain_M179S,WW_domain_179,Yap65,WW_domain,P46937,1.05912,NO,179,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.541,-3.163,1.622,6.54704,,,,,,,,,AHH,-1.31367,0.153962,0.00400164,1.05912 beta-lactamase_0_V82Q,beta-lactamase_0_82,TEM-1,beta-lactamase_0,P62593,1.05916,NO,82,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.325,-4.196,2.871,,0.267,H,A,0.44,0.08,1.893,,93.01,BHA,-1.28567,0.0500837,0.00397046,1.05916 PSD95pdz3_G335L,PSD95pdz3_335,PSD95pdz3,PSD95pdz3,P31016,1.05918,NO,335,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.008,-3.49,2.482,4.76223,,,,,22.4225,,,,AOH,-1.34733,0.0758425,0.000900493,1.05918 beta-lactamase_0_H24R,beta-lactamase_0_24,TEM-1,beta-lactamase_0,P62593,1.05919,NO,24,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-2.481,-3.749,1.268,,,,,,,2.708,,93.01,OBO,-2.0035,0.0500837,0.00238894,1.05919 gb1_Q228M,gb1_228,gb1,gb1,P06654,1.05923,NO,228,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,,,,,,,,,,,,,OPH,-1.282,0.177985,0.00391043,1.05923 beta-lactamase_0_L197P,beta-lactamase_0_197,TEM-1,beta-lactamase_0,P62593,1.05924,NO,197,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.853,-4.068,3.215,,0.007,S,B,0.55,0.33,1.087,,60.14,HHP,-1.833,0.0500837,0.00144602,1.05924 beta-lactamase_0_Q203T,beta-lactamase_0_203,TEM-1,beta-lactamase_0,P62593,1.05924,NO,203,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.168,-2.523,0.355,,0.47,H,A,0.64,-0.38,14.541,14.541,65.38,BPP,-1.614,0.0500837,0.00631514,1.05924 kka2_1:2_P98R,kka2_1:2_98,Kka2,kka2_1:2,P00552,1.05926,NO,98,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.526,-2.723,1.197,,0.391,S,B,0.52,-0.65,2.82,,63.26,HOO,-1.19167,0.295029,0.00622754,1.05926 kka2_1:2_A65L,kka2_1:2_65,Kka2,kka2_1:2,P00552,1.05932,NO,65,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.744,-2.62,0.876,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.295029,0.00709258,1.05932 beta-lactamase_0_F228L,beta-lactamase_0_228,TEM-1,beta-lactamase_0,P62593,1.05936,NO,228,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-2.342,-3.312,0.97,,0.154,E,B,0.58,-0.42,15.504,15.504,63.29,HHH,-1.53033,0.0500837,0.0046669,1.05936 PSD95pdz3_S320L,PSD95pdz3_320,PSD95pdz3,PSD95pdz3,P31016,1.05936,NO,320,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.519,-3.04,1.521,5.81757,,,,,21.4517,,,,OPP,-1.306,0.0758425,0.00108158,1.05936 beta-lactamase_0_Y44I,beta-lactamase_0_44,TEM-1,beta-lactamase_0,P62593,1.05937,NO,44,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-2.547,-2.364,-0.183,,,E,B,0.21,-0.45,1.751,,73.78,OHH,-1.86267,0.0500837,0.00426364,1.05937 kka2_1:8_Q136E,kka2_1:8_136,Kka2,kka2_1:8,P00552,1.05938,NO,136,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-3.021,-3.472,0.451,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.100394,0.00624149,1.05938 kka2_1:8_Q136E,kka2_1:8_136,Kka2,kka2_1:8,P00552,1.05938,NO,136,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-3.021,-3.472,0.451,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.100394,0.00624149,1.05938 kka2_1:8_E230G,kka2_1:8_230,Kka2,kka2_1:8,P00552,1.05939,NO,230,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.672,-3.574,0.902,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.100394,0.00920051,1.05939 kka2_1:8_E230G,kka2_1:8_230,Kka2,kka2_1:8,P00552,1.05939,NO,230,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.672,-3.574,0.902,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.100394,0.00920051,1.05939 kka2_1:4_L81V,kka2_1:4_81,Kka2,kka2_1:4,P00552,1.05941,NO,81,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.427,-1.839,0.412,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.168804,0.00805839,1.05941 PSD95pdz3_I338A,PSD95pdz3_338,PSD95pdz3,PSD95pdz3,P31016,1.05943,NO,338,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.63,-2.759,1.129,5.45113,,,,,13.0087,,,,HHP,-1.55767,0.0758425,0.000862587,1.05943 kka2_1:8_D33C,kka2_1:8_33,Kka2,kka2_1:8,P00552,1.05945,NO,33,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.186,-5.16,2.974,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.100394,0.00633568,1.05945 kka2_1:8_D33C,kka2_1:8_33,Kka2,kka2_1:8,P00552,1.05945,NO,33,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.186,-5.16,2.974,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.100394,0.00633568,1.05945 gb1_V255N,gb1_255,gb1,gb1,P06654,1.05946,NO,255,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-3.127,-3.561,0.434,,,,,,,1.323,,45.54,BHH,-2.03867,0.177985,0.00408354,1.05946 beta-lactamase_39_R91Y,beta-lactamase_39_91,TEM-1,beta-lactamase_39,P62593,1.05948,NO,91,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.392,-4.246,2.854,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.0495842,0.00380226,1.05948 beta-lactamase_39_D212E,beta-lactamase_39_212,TEM-1,beta-lactamase_39,P62593,1.05949,NO,212,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.624,-3.306,1.682,,0.037,,b,0.75,-0.58,10.748,10.748,74.48,HAB,-1.77667,0.0495842,0.00644302,1.05949 beta-lactamase_T112Q,beta-lactamase_112,TEM-1,beta-lactamase,P62593,1.05951,NO,112,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.186,-3.981,1.795,6.47162,0.921,T,A,0.77,1.06,2.04,,73.78,HPA,-1.925,0.221079,0.00531334,1.05951 kka2_1:8_I254Y,kka2_1:8_254,Kka2,kka2_1:8,P00552,1.05952,NO,254,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.933,-3.144,1.211,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.100394,0.0132375,1.05952 kka2_1:8_I254Y,kka2_1:8_254,Kka2,kka2_1:8,P00552,1.05952,NO,254,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.933,-3.144,1.211,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.100394,0.0132375,1.05952 kka2_1:2_E149D,kka2_1:2_149,Kka2,kka2_1:2,P00552,1.05953,NO,149,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.994,-2.359,0.365,,0.674,H,A,1.04,1.63,15.361,15.361,71.59,HAH,-1.59667,0.295029,0.00803343,1.05953 kka2_1:2_E160W,kka2_1:2_160,Kka2,kka2_1:2,P00552,1.05954,NO,160,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.683,-5.621,3.938,,0.989,G,A,1.04,2.28,3.948,,71.59,AAA,-1.36133,0.295029,0.00935762,1.05954 PSD95pdz3_Q384I,PSD95pdz3_384,PSD95pdz3,PSD95pdz3,P31016,1.05955,NO,384,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-1.699,-3.692,1.993,5.49339,,,,,23.54,,,,OPP,-1.41333,0.0758425,0.000216736,1.05955 beta-lactamase_39_V78N,beta-lactamase_39_78,TEM-1,beta-lactamase_39,P62593,1.05956,NO,78,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.459,-4.189,2.73,,,H,A,0.44,-0.47,1.132,,63.64,HHH,-1.17833,0.0495842,0.00492501,1.05956 beta-lactamase_39_I285C,beta-lactamase_39_285,TEM-1,beta-lactamase_39,P62593,1.05957,NO,285,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.0495842,0.101555,1.05957 kka2_1:4_D250H,kka2_1:4_250,Kka2,kka2_1:4,P00552,1.0596,NO,250,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.015,-4.493,3.478,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.168804,0.0177103,1.0596 kka2_1:8_V46R,kka2_1:8_46,Kka2,kka2_1:8,P00552,1.0596,NO,46,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-2.62,-2.74,0.12,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.100394,0.00631301,1.0596 kka2_1:8_V46R,kka2_1:8_46,Kka2,kka2_1:8,P00552,1.0596,NO,46,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-2.62,-2.74,0.12,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.100394,0.00631301,1.0596 beta-lactamase_K190D,beta-lactamase_190,TEM-1,beta-lactamase,P62593,1.05965,NO,190,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.994,-3.691,1.697,5.49163,0.371,H,A,1.82,0.16,29.753,29.753,77.62,BBH,-1.64167,0.221079,0.00574527,1.05965 beta-lactamase_39_I171M,beta-lactamase_39_171,TEM-1,beta-lactamase_39,P62593,1.05967,NO,171,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-2.431,-4.454,2.023,,0.361,,B,0.48,0.53,16.954,16.954,77.62,HHO,-1.55533,0.0495842,0.00623355,1.05967 gb1_V247W,gb1_247,gb1,gb1,P06654,1.05968,NO,247,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.711,-5.098,3.387,,,,,,,0.805,,44.87,HHA,-1.485,0.177985,0.00435373,1.05968 beta-lactamase_0_P181C,beta-lactamase_0_181,TEM-1,beta-lactamase_0,P62593,1.0597,NO,181,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.813,-5.009,4.196,,,H,A,0.52,-1.14,1.357,,61.54,HOH,-1.795,0.0500837,0.000703122,1.0597 kka2_1:2_Q26P,kka2_1:2_26,Kka2,kka2_1:2,P00552,1.05971,NO,26,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.18,-2.701,0.521,,0.448,E,B,0.4,0.44,5.022,,92.05,HPP,-2.11167,0.295029,0.00708962,1.05971 beta-lactamase_39_L205Q,beta-lactamase_39_205,TEM-1,beta-lactamase_39,P62593,1.05976,NO,205,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.922,-4.179,3.257,,,H,A,0.55,-0.46,0.846,,42.31,PHH,-1.57767,0.0495842,0.00255802,1.05976 kka2_1:8_E235N,kka2_1:8_235,Kka2,kka2_1:8,P00552,1.0598,NO,235,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.955,-3.12,1.165,,0.631,H,A,1.52,0.12,,,65.53,OAH,-2.07267,0.100394,0.0102806,1.0598 kka2_1:8_E235N,kka2_1:8_235,Kka2,kka2_1:8,P00552,1.0598,NO,235,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.955,-3.12,1.165,,0.631,H,A,1.52,0.12,,,65.53,OAH,-2.07267,0.100394,0.0102806,1.0598 kka2_1:8_Q136N,kka2_1:8_136,Kka2,kka2_1:8,P00552,1.05985,NO,136,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-3.021,-3.645,0.624,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.100394,0.00624149,1.05985 kka2_1:8_Q136N,kka2_1:8_136,Kka2,kka2_1:8,P00552,1.05985,NO,136,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-3.021,-3.645,0.624,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.100394,0.00624149,1.05985 beta-lactamase_625_E87A,beta-lactamase_625_87,TEM-1,beta-lactamase_625,P62593,1.05987,NO,87,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.421,-3.209,1.788,,0.048,,B,1.04,0.92,17.923,17.923,64.69,PAP,-1.969,0.213352,0.00337888,1.05987 kka2_1:4_M116A,kka2_1:4_116,Kka2,kka2_1:4,P00552,1.05987,NO,116,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-2.482,-2.16,-0.322,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.168804,0.00745147,1.05987 gb1_E241W,gb1_241,gb1,gb1,P06654,1.0599,NO,241,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.672,-5.133,3.461,,,,,,,0.344,,11.83,OAP,-1.27933,0.177985,0.00250604,1.0599 kka2_1:4_E96A,kka2_1:4_96,Kka2,kka2_1:4,P00552,1.0599,NO,96,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.573,-1.097,-1.476,,0.476,,B,1.52,-0.65,1.254,,71.59,OAH,-2.143,0.168804,0.00369441,1.0599 beta-lactamase_39_S201C,beta-lactamase_39_201,TEM-1,beta-lactamase_39,P62593,1.05993,NO,201,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.183,-4.753,3.57,,0.064,H,A,0.27,-0.07,3.54,,64.69,HPB,-1.451,0.0495842,0.00198815,1.05993 kka2_1:4_E142G,kka2_1:4_142,Kka2,kka2_1:4,P00552,1.06005,NO,142,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.221,-2.713,0.492,,0.471,H,A,1.52,0.85,3.693,,65.53,HAB,-2.08033,0.168804,0.00748883,1.06005 beta-lactamase_0_Q86Y,beta-lactamase_0_86,TEM-1,beta-lactamase_0,P62593,1.06008,NO,86,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.4,-4.372,1.972,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.0500837,0.00450027,1.06008 gb1_D262L,gb1_262,gb1,gb1,P06654,1.06012,NO,262,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-3.132,-3.252,0.12,,,,,,,1.304,,45.54,PAP,-2.05233,0.177985,0.00413102,1.06012 kka2_1:4_Q136D,kka2_1:4_136,Kka2,kka2_1:4,P00552,1.06017,NO,136,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-3.021,-3.719,0.698,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.168804,0.00624149,1.06017 PSD95pdz3_S361W,PSD95pdz3_361,PSD95pdz3,PSD95pdz3,P31016,1.06019,NO,361,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.519,-5.004,3.485,4.8722,,,,,16.4533,,,,HPH,-1.47167,0.0758425,0.00055296,1.06019 PSD95pdz3_I314D,PSD95pdz3_314,PSD95pdz3,PSD95pdz3,P31016,1.06022,NO,314,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.628,-3.696,2.068,5.39919,,,,,15.7775,0.397,,81.35,BHH,-1.61167,0.0758425,0.0012606,1.06022 gb1_T243W,gb1_243,gb1,gb1,P06654,1.06023,NO,243,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.415,-4.978,3.563,,,,,,,1.083,,37.28,PPP,-1.43233,0.177985,0.00308687,1.06023 kka2_1:8_G43S,kka2_1:8_43,Kka2,kka2_1:8,P00552,1.06023,NO,43,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.587,-2.69,1.103,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.100394,0.0071925,1.06023 kka2_1:8_G43S,kka2_1:8_43,Kka2,kka2_1:8,P00552,1.06023,NO,43,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.587,-2.69,1.103,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.100394,0.0071925,1.06023 PSD95pdz3_V315D,PSD95pdz3_315,PSD95pdz3,PSD95pdz3,P31016,1.06023,NO,315,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.625,-3.818,2.193,5.52024,,,,,18.4557,4.054,,81.35,HHH,-1.62767,0.0758425,0.00153536,1.06023 beta-lactamase_0_T27V,beta-lactamase_0_27,TEM-1,beta-lactamase_0,P62593,1.06027,NO,27,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.905,-3.409,1.504,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.0500837,0.00306559,1.06027 kka2_1:8_Q163K,kka2_1:8_163,Kka2,kka2_1:8,P00552,1.06027,NO,163,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.162,-2.924,0.762,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.100394,0.00719507,1.06027 kka2_1:8_Q163K,kka2_1:8_163,Kka2,kka2_1:8,P00552,1.06027,NO,163,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.162,-2.924,0.762,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.100394,0.00719507,1.06027 beta-lactamase_0_V101E,beta-lactamase_0_101,TEM-1,beta-lactamase_0,P62593,1.06037,NO,101,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.295,-2.851,1.556,,0.342,,B,0.44,0,1.61,,73.08,HHA,-1.54367,0.0500837,0.00374492,1.06037 kka2_1:8_D90H,kka2_1:8_90,Kka2,kka2_1:8,P00552,1.06038,NO,90,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.459,-2.113,-0.346,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.100394,0.00583842,1.06038 kka2_1:8_D90H,kka2_1:8_90,Kka2,kka2_1:8,P00552,1.06038,NO,90,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.459,-2.113,-0.346,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.100394,0.00583842,1.06038 beta-lactamase_39_V106S,beta-lactamase_39_106,TEM-1,beta-lactamase_39,P62593,1.06045,NO,106,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.218,-3.705,2.487,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.0495842,0.00304168,1.06045 gb1_Q228W,gb1_228,gb1,gb1,P06654,1.06045,NO,228,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,,,,,,,,,,,,,OPH,-1.282,0.177985,0.00391043,1.06045 kka2_1:2_I2Q,kka2_1:2_2,Kka2,kka2_1:2,P00552,1.06047,NO,2,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.787,-3.979,2.192,,,,,,,5.773,,71.59,HHA,-1.92433,0.295029,0.00246644,1.06047 beta-lactamase_39_I93Y,beta-lactamase_39_93,TEM-1,beta-lactamase_39,P62593,1.06054,NO,93,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.401,-4.112,2.711,,0.128,E,B,0.48,0.44,1.757,,67.83,BHB,-1.873,0.0495842,0.00527066,1.06054 kka2_1:2_D156T,kka2_1:2_156,Kka2,kka2_1:2,P00552,1.06057,NO,156,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.696,-1.988,0.292,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.295029,0.00926998,1.06057 beta-lactamase_625_D212Q,beta-lactamase_625_212,TEM-1,beta-lactamase_625,P62593,1.06061,NO,212,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.624,-3.949,2.325,,0.037,,b,0.75,-0.58,1.516,,74.48,HAB,-1.77667,0.213352,0.00644302,1.06061 kka2_1:2_A176G,kka2_1:2_176,Kka2,kka2_1:2,P00552,1.06061,NO,176,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.621,-3.323,1.702,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.295029,0.0083587,1.06061 PSD95pdz3_T321E,PSD95pdz3_321,PSD95pdz3,PSD95pdz3,P31016,1.06061,NO,321,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.391,-3.122,1.731,5.19953,,,,,20.3371,,,,PPO,-1.306,0.0758425,0.00106992,1.06061 beta-lactamase_0_R189V,beta-lactamase_0_189,TEM-1,beta-lactamase_0,P62593,1.06066,NO,189,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.844,-3.783,1.939,,0.278,H,A,1.2,1.01,12.11,12.11,72.73,HBB,-1.668,0.0500837,0.0050699,1.06066 beta-lactamase_0_A225C,beta-lactamase_0_225,TEM-1,beta-lactamase_0,P62593,1.06073,NO,225,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.845,-5.105,3.26,,1,T,B,0.46,-0.38,11.722,11.722,74.48,OHO,-1.39967,0.0500837,0.00465057,1.06073 beta-lactamase_0_G234I,beta-lactamase_0_234,TEM-1,beta-lactamase_0,P62593,1.06076,NO,234,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.62,-4.235,3.615,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.0500837,0.000889577,1.06076 gb1_D262T,gb1_262,gb1,gb1,P06654,1.06078,NO,262,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-3.132,-3.157,0.025,,,,,,,1.304,,45.54,PAP,-2.05233,0.177985,0.00413102,1.06078 gb1_V265L,gb1_265,gb1,gb1,P06654,1.06078,NO,265,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.843,-2.97,1.127,,,,,,,0.402,,11.83,OHA,-1.64567,0.177985,0.00360613,1.06078 kka2_1:8_G151S,kka2_1:8_151,Kka2,kka2_1:8,P00552,1.06078,NO,151,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.873,-2.614,1.741,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.100394,0.00339918,1.06078 kka2_1:8_G151S,kka2_1:8_151,Kka2,kka2_1:8,P00552,1.06078,NO,151,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.873,-2.614,1.741,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.100394,0.00339918,1.06078 beta-lactamase_39_F149W,beta-lactamase_39_149,TEM-1,beta-lactamase_39,P62593,1.06081,NO,149,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.299,-2.98,1.681,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.0495842,0.00418462,1.06081 beta-lactamase_39_I93A,beta-lactamase_39_93,TEM-1,beta-lactamase_39,P62593,1.06081,NO,93,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.401,-3.13,1.729,,0.128,E,B,0.48,0.44,1.757,,67.83,BHB,-1.873,0.0495842,0.00527066,1.06081 kka2_1:8_A79T,kka2_1:8_79,Kka2,kka2_1:8,P00552,1.06083,NO,79,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.368,-2.485,0.117,,0.563,.,B,0.46,-0.43,,,71.59,HHH,-1.752,0.100394,0.00664821,1.06083 kka2_1:8_A79T,kka2_1:8_79,Kka2,kka2_1:8,P00552,1.06083,NO,79,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.368,-2.485,0.117,,0.563,.,B,0.46,-0.43,,,71.59,HHH,-1.752,0.100394,0.00664821,1.06083 PSD95pdz3_S350H,PSD95pdz3_350,PSD95pdz3,PSD95pdz3,P31016,1.06087,NO,350,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.519,-4.137,2.618,4.97629,,,,,25.01,,,,HPO,-1.29133,0.0758425,0.000704883,1.06087 beta-lactamase_T262Y,beta-lactamase_262,TEM-1,beta-lactamase,P62593,1.06092,NO,262,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.332,-4.271,2.939,5.06002,0.108,E,B,0.3,-0.55,1.423,,67.83,PPO,-2.081,0.221079,0.00853516,1.06092 beta-lactamase_0_T126K,beta-lactamase_0_126,TEM-1,beta-lactamase_0,P62593,1.06096,NO,126,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.122,-3.536,2.414,,0.05,H,A,0.22,-0.05,0.705,,44.41,HPH,-1.60467,0.0500837,0.00244552,1.06096 kka2_1:4_G234C,kka2_1:4_234,Kka2,kka2_1:4,P00552,1.06098,NO,234,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-2.9,-5.225,2.325,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.168804,0.00984449,1.06098 beta-lactamase_0_D33L,beta-lactamase_0_33,TEM-1,beta-lactamase_0,P62593,1.06099,NO,33,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.321,-2.326,0.005,,0.366,H,A,0.75,0.33,12.514,12.514,77.62,BAH,-2.12133,0.0500837,0.00435556,1.06099 gb1_E245A,gb1_245,gb1,gb1,P06654,1.061,NO,245,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.725,-2.813,0.088,,,,,,,0.712,,45.54,PAH,-1.84567,0.177985,0.00158611,1.061 beta-lactamase_0_I93W,beta-lactamase_0_93,TEM-1,beta-lactamase_0,P62593,1.06101,NO,93,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.401,-5.418,4.017,,0.128,E,B,0.48,0.44,1.266,,67.83,BHB,-1.873,0.0500837,0.00527066,1.06101 E1_Ubiquitin_L73V,E1_Ubiquitin_73,Uba1,E1_Ubiquitin,P0CG63,1.06101,NO,73,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.039,-2.671,1.632,,0.518,,B,1.3,1,,,,BHB,-1.175,0.18783,0.00111236,1.06101 beta-lactamase_39_N130C,beta-lactamase_39_130,TEM-1,beta-lactamase_39,P62593,1.06105,NO,130,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-0.798,-5.087,4.289,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.0495842,0.000683376,1.06105 kka2_1:4_V83G,kka2_1:4_83,Kka2,kka2_1:4,P00552,1.06107,NO,83,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-2.567,-3.646,1.079,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.168804,0.00650486,1.06107 beta-lactamase_0_R118W,beta-lactamase_0_118,TEM-1,beta-lactamase_0,P62593,1.06108,NO,118,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.413,-5.439,3.026,,0.457,H,A,1.2,1.39,3.961,,77.62,HBA,-1.785,0.0500837,0.00538794,1.06108 beta-lactamase_0_E46I,beta-lactamase_0_46,TEM-1,beta-lactamase_0,P62593,1.06109,NO,46,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.94,-2.064,0.124,,0.021,E,B,1.04,0.14,30.306,30.306,59.44,HAH,-2.079,0.0500837,0.00427568,1.06109 kka2_1:8_M148L,kka2_1:8_148,Kka2,kka2_1:8,P00552,1.0611,NO,148,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.847,-2.054,0.207,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.100394,0.00982664,1.0611 kka2_1:8_M148L,kka2_1:8_148,Kka2,kka2_1:8,P00552,1.0611,NO,148,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.847,-2.054,0.207,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.100394,0.00982664,1.0611 kka2_1:8_T73Y,kka2_1:8_73,Kka2,kka2_1:8,P00552,1.0611,NO,73,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.51,-3.328,0.818,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.100394,0.00628605,1.0611 kka2_1:8_T73Y,kka2_1:8_73,Kka2,kka2_1:8,P00552,1.0611,NO,73,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.51,-3.328,0.818,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.100394,0.00628605,1.0611 gb1_A250I,gb1_250,gb1,gb1,P06654,1.06111,NO,250,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.713,-3.683,1.97,,,,,,,3.465,,45.54,HHP,-1.74867,0.177985,0.00332003,1.06111 gb1_T270A,gb1_270,gb1,gb1,P06654,1.06111,NO,270,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-3.15,-2.028,-1.122,,,,,,,1.326,,45.54,HPH,-1.843,0.177985,0.00223707,1.06111 kka2_1:4_T51A,kka2_1:4_51,Kka2,kka2_1:4,P00552,1.06117,NO,51,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.199,-2.346,0.147,,0.05,E,B,0.82,-0.05,13.165,13.165,63.64,BPA,-1.76767,0.168804,0.00628861,1.06117 kka2_1:2_L165R,kka2_1:2_165,Kka2,kka2_1:2,P00552,1.06125,NO,165,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-2.453,-2.067,-0.386,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.295029,0.00801161,1.06125 kka2_1:2_G95S,kka2_1:2_95,Kka2,kka2_1:2,P00552,1.06126,NO,95,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-2.403,-1.66,-0.743,,0.126,E,B,0.29,-0.74,0.359,,71.59,HOA,-2.198,0.295029,0.00743616,1.06126 kka2_1:8_C77S,kka2_1:8_77,Kka2,kka2_1:8,P00552,1.06132,NO,77,C,S,CS,Special,Polar,5.07,5.68,0.61,112,121,105,-16,108.5,89,-19.5,-1.477,-2.746,1.269,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.100394,0.00441216,1.06132 kka2_1:8_C77S,kka2_1:8_77,Kka2,kka2_1:8,P00552,1.06132,NO,77,C,S,CS,Special,Polar,5.07,5.68,0.61,112,121,105,-16,108.5,89,-19.5,-1.477,-2.746,1.269,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.100394,0.00441216,1.06132 kka2_1:4_G164R,kka2_1:4_164,Kka2,kka2_1:4,P00552,1.06133,NO,164,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.869,-3.953,3.084,,0.862,T,l,0.75,1.45,1.539,,64.39,POH,-1.828,0.168804,0.00442091,1.06133 kka2_1:8_D90Q,kka2_1:8_90,Kka2,kka2_1:8,P00552,1.06134,NO,90,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.459,-2.781,0.322,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.100394,0.00583842,1.06134 kka2_1:8_D90Q,kka2_1:8_90,Kka2,kka2_1:8,P00552,1.06134,NO,90,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.459,-2.781,0.322,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.100394,0.00583842,1.06134 kka2_1:2_E17G,kka2_1:2_17,Kka2,kka2_1:2,P00552,1.06135,NO,17,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.154,-2.597,0.443,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.295029,0.00688738,1.06135 kka2_1:8_R173L,kka2_1:8_173,Kka2,kka2_1:8,P00552,1.06138,NO,173,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.407,-2.806,0.399,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.100394,0.00784999,1.06138 kka2_1:8_R173L,kka2_1:8_173,Kka2,kka2_1:8,P00552,1.06138,NO,173,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.407,-2.806,0.399,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.100394,0.00784999,1.06138 beta-lactamase_0_R242D,beta-lactamase_0_242,TEM-1,beta-lactamase_0,P62593,1.06139,NO,242,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.0500837,0.00452879,1.06139 PSD95pdz3_R354Q,PSD95pdz3_354,PSD95pdz3,PSD95pdz3,P31016,1.06144,NO,354,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.582,-3.131,1.549,6.21887,,,,,23.7791,,,,HBB,-1.44833,0.0758425,0.000650924,1.06144 beta-lactamase_39_I171V,beta-lactamase_39_171,TEM-1,beta-lactamase_39,P62593,1.06149,NO,171,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-2.431,-3.274,0.843,,0.361,,B,0.48,0.53,16.954,16.954,77.62,HHO,-1.55533,0.0495842,0.00623355,1.06149 beta-lactamase_39_W208Q,beta-lactamase_39_208,TEM-1,beta-lactamase_39,P62593,1.0615,NO,208,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-0.818,-4.124,3.306,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.0495842,0.00126609,1.0615 beta-lactamase_39_H110T,beta-lactamase_39_110,TEM-1,beta-lactamase_39,P62593,1.06154,NO,110,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-1.706,-3.697,1.991,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.0495842,0.00441499,1.06154 kka2_1:8_Q61R,kka2_1:8_61,Kka2,kka2_1:8,P00552,1.06155,NO,61,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.982,-2.952,-0.03,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.100394,0.00612092,1.06155 kka2_1:8_Q61R,kka2_1:8_61,Kka2,kka2_1:8,P00552,1.06155,NO,61,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.982,-2.952,-0.03,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.100394,0.00612092,1.06155 kka2_1:8_I246T,kka2_1:8_246,Kka2,kka2_1:8,P00552,1.06169,NO,246,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-2.008,-3.038,1.03,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.100394,0.0139479,1.06169 kka2_1:8_I246T,kka2_1:8_246,Kka2,kka2_1:8,P00552,1.06169,NO,246,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-2.008,-3.038,1.03,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.100394,0.0139479,1.06169 PSD95pdz3_P311A,PSD95pdz3_311,PSD95pdz3,PSD95pdz3,P31016,1.06171,NO,311,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.236,-2.759,1.523,5.76649,,,,,14.78,,,,OOB,-1.409,0.0758425,0.0030796,1.06171 kka2_1:8_E111I,kka2_1:8_111,Kka2,kka2_1:8,P00552,1.06176,NO,111,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.28,-4.031,1.751,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.100394,0.00746789,1.06176 kka2_1:8_E111I,kka2_1:8_111,Kka2,kka2_1:8,P00552,1.06176,NO,111,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.28,-4.031,1.751,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.100394,0.00746789,1.06176 PSD95pdz3_G319E,PSD95pdz3_319,PSD95pdz3,PSD95pdz3,P31016,1.06182,NO,319,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.008,-3.347,2.339,4.95387,,,,,18.8725,,,,BOP,-1.36967,0.0758425,0.00109317,1.06182 beta-lactamase_Y103W,beta-lactamase_103,TEM-1,beta-lactamase,P62593,1.06189,NO,103,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-1.33,-2.453,1.123,5.71734,0.613,S,l,2.55,1.21,5.721,,63.29,AHP,-1.48767,0.221079,0.00443048,1.06189 PSD95pdz3_I314L,PSD95pdz3_314,PSD95pdz3,PSD95pdz3,P31016,1.06194,NO,314,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.628,-2.319,0.691,5.39919,,,,,15.7775,0.397,,81.35,BHH,-1.61167,0.0758425,0.0012606,1.06194 beta-lactamase_0_D129P,beta-lactamase_0_129,TEM-1,beta-lactamase_0,P62593,1.06196,NO,129,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.816,-3.68,2.864,,,,B,0.75,-0.69,2.66,,34.97,PAP,-0.818,0.0500837,0.00109178,1.06196 gb1_E241T,gb1_241,gb1,gb1,P06654,1.06199,NO,241,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.672,-3.114,1.442,,,,,,,0.344,,11.83,OAP,-1.27933,0.177985,0.00250604,1.06199 kka2_1:4_S105T,kka2_1:4_105,Kka2,kka2_1:4,P00552,1.06199,NO,105,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.945,-2.444,0.499,,0.056,S,B,0.77,-1.04,3.442,,65.53,PPB,-2.17033,0.168804,0.00847233,1.06199 beta-lactamase_625_K190N,beta-lactamase_625_190,TEM-1,beta-lactamase_625,P62593,1.06201,NO,190,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.994,-2.601,0.607,,0.371,H,A,2.34,0.16,29.753,29.753,77.62,BBH,-1.64167,0.213352,0.00574527,1.06201 beta-lactamase_39_G141S,beta-lactamase_39_141,TEM-1,beta-lactamase_39,P62593,1.06203,NO,141,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.828,-3.221,2.393,,0.575,T,l,0.29,-0.28,0.722,,64.69,HOO,-1.08933,0.0495842,0.0012419,1.06203 beta-lactamase_39_P255I,beta-lactamase_39_255,TEM-1,beta-lactamase_39,P62593,1.06203,NO,255,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.0495842,0.00499612,1.06203 kka2_1:4_T146W,kka2_1:4_146,Kka2,kka2_1:4,P00552,1.06209,NO,146,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.978,-5.546,2.568,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.168804,0.00606474,1.06209 beta-lactamase_0_R162G,beta-lactamase_0_162,TEM-1,beta-lactamase_0,P62593,1.0621,NO,162,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.016,-3.445,2.429,,0.124,S,B,1.2,-0.37,1.026,,64.69,ABH,-1.25,0.0500837,0.000561334,1.0621 PSD95pdz3_G333I,PSD95pdz3_333,PSD95pdz3,PSD95pdz3,P31016,1.06211,NO,333,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.008,-3.917,2.909,5.09445,,,,,48.755,,,,AOA,-1.22533,0.0758425,0.00092544,1.06211 beta-lactamase_39_H151N,beta-lactamase_39_151,TEM-1,beta-lactamase_39,P62593,1.06222,NO,151,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-2.96,-3.49,0.53,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.0495842,0.00216946,1.06222 beta-lactamase_0_M270R,beta-lactamase_0_270,TEM-1,beta-lactamase_0,P62593,1.06226,NO,270,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.0500837,0.00767762,1.06226 beta-lactamase_0_Q203W,beta-lactamase_0_203,TEM-1,beta-lactamase_0,P62593,1.06226,NO,203,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.168,-5.466,3.298,,0.47,H,A,0.64,-0.38,14.541,14.541,65.38,BPP,-1.614,0.0500837,0.00631514,1.06226 PSD95pdz3_R313E,PSD95pdz3_313,PSD95pdz3,PSD95pdz3,P31016,1.06227,NO,313,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.582,-2.897,1.315,6.63563,,,,,18.3955,,,,BBH,-1.59733,0.0758425,0.000840067,1.06227 beta-lactamase_V8S,beta-lactamase_8,TEM-1,beta-lactamase,P62593,1.0623,NO,8,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-2.358,-3.467,1.109,,,,,,,0.575,,77.62,BHH,-2.06267,0.221079,0.00226401,1.0623 PSD95pdz3_V328I,PSD95pdz3_328,PSD95pdz3,PSD95pdz3,P31016,1.06231,NO,328,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.465,-2.342,0.877,5.28275,,,,,16.8775,,,,HHO,-1.36767,0.0758425,0.000986706,1.06231 kka2_1:4_A137I,kka2_1:4_137,Kka2,kka2_1:4,P00552,1.06234,NO,137,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.156,-2.375,0.219,,0.029,H,A,0.46,0.34,2.227,,63.26,PHB,-2.559,0.168804,0.00515054,1.06234 beta-lactamase_0_A282R,beta-lactamase_0_282,TEM-1,beta-lactamase_0,P62593,1.06239,NO,282,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.0500837,0.0449821,1.06239 beta-lactamase_0_E108Y,beta-lactamase_0_108,TEM-1,beta-lactamase_0,P62593,1.06239,NO,108,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.46,-4.347,2.887,,0.572,G,A,1.04,1.87,8.602,8.602,72.73,PAB,-1.437,0.0500837,0.00413372,1.06239 beta-lactamase_625_D212G,beta-lactamase_625_212,TEM-1,beta-lactamase_625,P62593,1.06245,NO,212,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.624,-2.198,0.574,,0.037,,b,0.75,-0.58,1.516,,74.48,HAB,-1.77667,0.213352,0.00644302,1.06245 beta-lactamase_156_A215M,beta-lactamase_156_215,TEM-1,beta-lactamase_156,P62593,1.0625,NO,215,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.503,-4.708,3.205,,,,a,0.46,-0.93,3.583,,74.48,HHO,-1.42633,0.111618,0.00544007,1.0625 kka2_1:8_R18V,kka2_1:8_18,Kka2,kka2_1:8,P00552,1.06252,NO,18,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.055,-3.089,1.034,,0.474,T,A,1.2,0.54,19.629,19.629,71.59,ABH,-1.821,0.100394,0.00724065,1.06252 kka2_1:8_R18V,kka2_1:8_18,Kka2,kka2_1:8,P00552,1.06252,NO,18,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.055,-3.089,1.034,,0.474,T,A,1.2,0.54,19.629,19.629,71.59,ABH,-1.821,0.100394,0.00724065,1.06252 kka2_1:8_T51Y,kka2_1:8_51,Kka2,kka2_1:8,P00552,1.06252,NO,51,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.199,-4.283,2.084,,0.05,E,B,0.82,-0.05,5.399,,63.64,BPA,-1.76767,0.100394,0.00628861,1.06252 kka2_1:8_T51Y,kka2_1:8_51,Kka2,kka2_1:8,P00552,1.06252,NO,51,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.199,-4.283,2.084,,0.05,E,B,0.82,-0.05,5.399,,63.64,BPA,-1.76767,0.100394,0.00628861,1.06252 beta-lactamase_0_D99P,beta-lactamase_0_99,TEM-1,beta-lactamase_0,P62593,1.06253,NO,99,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.191,-3.8,2.609,,0.402,G,A,0.75,0.36,0.374,,64.69,PAH,-1.794,0.0500837,0.00305446,1.06253 beta-lactamase_39_I171Y,beta-lactamase_39_171,TEM-1,beta-lactamase_39,P62593,1.06254,NO,171,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-2.431,-4.204,1.773,,0.361,,B,0.48,0.53,16.954,16.954,77.62,HHO,-1.55533,0.0495842,0.00623355,1.06254 kka2_1:2_T146C,kka2_1:2_146,Kka2,kka2_1:2,P00552,1.06254,NO,146,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.978,-5.009,2.031,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.295029,0.00606474,1.06254 gb1_T251S,gb1_251,gb1,gb1,P06654,1.06265,NO,251,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.794,-3.022,1.228,,,,,,,3.514,3.514,37.28,HPH,-1.56067,0.177985,0.00232932,1.06265 kka2_1:8_G55W,kka2_1:8_55,Kka2,kka2_1:8,P00552,1.06265,NO,55,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.625,-5.446,3.821,,0.517,S,b,0.29,1.19,8.881,,63.64,POH,-2.05967,0.100394,0.00667877,1.06265 kka2_1:8_G55W,kka2_1:8_55,Kka2,kka2_1:8,P00552,1.06265,NO,55,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.625,-5.446,3.821,,0.517,S,b,0.29,1.19,8.881,,63.64,POH,-2.05967,0.100394,0.00667877,1.06265 kka2_1:8_V80Y,kka2_1:8_80,Kka2,kka2_1:8,P00552,1.06267,NO,80,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.144,-4.109,2.965,,0.358,E,B,1.48,-0.24,2.562,,63.64,HHH,-1.64633,0.100394,0.00488211,1.06267 kka2_1:8_V80Y,kka2_1:8_80,Kka2,kka2_1:8,P00552,1.06267,NO,80,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.144,-4.109,2.965,,0.358,E,B,1.48,-0.24,2.562,,63.64,HHH,-1.64633,0.100394,0.00488211,1.06267 beta-lactamase_0_L196T,beta-lactamase_0_196,TEM-1,beta-lactamase_0,P62593,1.06268,NO,196,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-2.478,-2.588,0.11,,0.518,S,A,0.55,1.35,6.513,6.513,77.62,AHH,-1.839,0.0500837,0.00512144,1.06268 kka2_1:8_V198E,kka2_1:8_198,Kka2,kka2_1:8,P00552,1.06268,NO,198,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.719,-2.905,1.186,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.100394,0.00835002,1.06268 kka2_1:8_V198E,kka2_1:8_198,Kka2,kka2_1:8,P00552,1.06268,NO,198,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.719,-2.905,1.186,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.100394,0.00835002,1.06268 kka2_1:8_Q252K,kka2_1:8_252,Kka2,kka2_1:8,P00552,1.06269,NO,252,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.63,-2.767,0.137,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.100394,0.0121001,1.06269 kka2_1:8_Q252K,kka2_1:8_252,Kka2,kka2_1:8,P00552,1.06269,NO,252,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.63,-2.767,0.137,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.100394,0.0121001,1.06269 beta-lactamase_0_T112S,beta-lactamase_0_112,TEM-1,beta-lactamase_0,P62593,1.06279,NO,112,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.186,-2.762,0.576,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.0500837,0.00531334,1.06279 kka2_1:2_E142K,kka2_1:2_142,Kka2,kka2_1:2,P00552,1.06288,NO,142,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.221,-3.543,1.322,,0.471,H,A,1.52,0.85,3.693,,65.53,HAB,-2.08033,0.295029,0.00748883,1.06288 kka2_1:2_V84I,kka2_1:2_84,Kka2,kka2_1:2,P00552,1.06292,NO,84,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-2.279,-2.844,0.565,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.295029,0.00724019,1.06292 beta-lactamase_0_G90Q,beta-lactamase_0_90,TEM-1,beta-lactamase_0,P62593,1.06297,NO,90,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-2.091,-2.862,0.771,,0.598,T,A,0.29,0.32,2.04,,77.62,HOB,-1.52633,0.0500837,0.00490273,1.06297 kka2_1:8_N200R,kka2_1:8_200,Kka2,kka2_1:8,P00552,1.06303,NO,200,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-2.446,-3.001,0.555,,0.756,T,L,0.43,-0.08,2.528,,64.39,APO,-2.08,0.100394,0.00838549,1.06303 kka2_1:8_N200R,kka2_1:8_200,Kka2,kka2_1:8,P00552,1.06303,NO,200,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-2.446,-3.001,0.555,,0.756,T,L,0.43,-0.08,2.528,,64.39,APO,-2.08,0.100394,0.00838549,1.06303 kka2_1:8_F206Y,kka2_1:8_206,Kka2,kka2_1:8,P00552,1.06305,NO,206,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.349,-1.759,0.41,,0.006,E,B,1.62,-1.21,1.052,,63.64,OHH,-1.04,0.100394,0.00936868,1.06305 kka2_1:8_F206Y,kka2_1:8_206,Kka2,kka2_1:8,P00552,1.06305,NO,206,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.349,-1.759,0.41,,0.006,E,B,1.62,-1.21,1.052,,63.64,OHH,-1.04,0.100394,0.00936868,1.06305 kka2_1:2_Q155D,kka2_1:2_155,Kka2,kka2_1:2,P00552,1.0631,NO,155,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.606,-2.377,-0.229,,0.525,T,A,0.64,1.49,1.592,,63.64,APA,-1.726,0.295029,0.00641853,1.0631 beta-lactamase_0_L73Q,beta-lactamase_0_73,TEM-1,beta-lactamase_0,P62593,1.06313,NO,73,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.507,-4.261,2.754,,,H,A,0.55,-0.64,0.877,,67.83,HHH,-1.487,0.0500837,0.00488983,1.06313 PSD95pdz3_T385V,PSD95pdz3_385,PSD95pdz3,PSD95pdz3,P31016,1.06313,NO,385,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.533,-3.012,1.479,5.57157,,,,,23.6871,4.527,,87.71,PPH,-1.56567,0.0758425,0.000545119,1.06313 PSD95pdz3_E334Q,PSD95pdz3_334,PSD95pdz3,PSD95pdz3,P31016,1.06315,NO,334,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.404,-2.906,1.502,5.60175,,,,,53.09,,,,OAO,-1.14,0.0758425,0.000912998,1.06315 kka2_1:8_L126V,kka2_1:8_126,Kka2,kka2_1:8,P00552,1.06317,NO,126,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.246,-1.955,0.709,,0.285,S,B,1.59,0.12,4.443,,51.89,PHA,-1.744,0.100394,0.0066485,1.06317 kka2_1:8_L126V,kka2_1:8_126,Kka2,kka2_1:8,P00552,1.06317,NO,126,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.246,-1.955,0.709,,0.285,S,B,1.59,0.12,4.443,,51.89,PHA,-1.744,0.100394,0.0066485,1.06317 PSD95pdz3_T321R,PSD95pdz3_321,PSD95pdz3,PSD95pdz3,P31016,1.06318,NO,321,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.391,-3.39,1.999,5.19953,,,,,20.3371,,,,PPO,-1.306,0.0758425,0.00106992,1.06318 kka2_1:4_L126V,kka2_1:4_126,Kka2,kka2_1:4,P00552,1.06322,NO,126,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.246,-1.955,0.709,,0.285,S,B,0.55,0.12,0.302,,51.89,PHA,-1.744,0.168804,0.0066485,1.06322 beta-lactamase_0_L191C,beta-lactamase_0_191,TEM-1,beta-lactamase_0,P62593,1.06334,NO,191,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.087,-4.696,3.609,,,H,A,0.55,0.09,12.255,12.255,63.29,BHH,-1.445,0.0500837,0.00263549,1.06334 beta-lactamase_39_F58K,beta-lactamase_39_58,TEM-1,beta-lactamase_39,P62593,1.06334,NO,58,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-2.914,-3.623,0.709,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.0495842,0.00523369,1.06334 kka2_1:1_V242A,kka2_1:1_242,Kka2,kka2_1:1,P00552,1.06336,NO,242,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-2.687,-2.142,-0.545,,0.75,H,A,0.44,-0.37,4.987,,71.59,HHH,-2.16533,0.520039,0.0102575,1.06336 PSD95pdz3_L353F,PSD95pdz3_353,PSD95pdz3,PSD95pdz3,P31016,1.06336,NO,353,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.347,-3.299,1.952,5.81136,,,,,17.3525,,,,AHB,-1.50533,0.0758425,0.000664742,1.06336 beta-lactamase_39_F58D,beta-lactamase_39_58,TEM-1,beta-lactamase_39,P62593,1.06339,NO,58,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-2.914,-3.846,0.932,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.0495842,0.00523369,1.06339 WW_domain_T196R,WW_domain_196,Yap65,WW_domain,P46937,1.06341,NO,196,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.782,-2.57,0.788,5.5744,,,,,,5.836,,70.04,PPP,-1.732,0.153962,0.00421377,1.06341 PSD95pdz3_S320D,PSD95pdz3_320,PSD95pdz3,PSD95pdz3,P31016,1.06343,NO,320,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.519,-2.925,1.406,5.81757,,,,,21.4517,,,,OPP,-1.306,0.0758425,0.00108158,1.06343 beta-lactamase_0_L192F,beta-lactamase_0_192,TEM-1,beta-lactamase_0,P62593,1.06351,NO,192,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.254,-2.572,1.318,,0.095,H,A,0.55,0.35,1.756,,60.14,HHP,-1.41833,0.0500837,0.00558728,1.06351 gb1_D248G,gb1_248,gb1,gb1,P06654,1.06352,NO,248,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.569,-2.825,1.256,,,,,,,0.344,,11.83,HAH,-1.673,0.177985,0.001865,1.06352 gb1_E245Q,gb1_245,gb1,gb1,P06654,1.06352,NO,245,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.725,-3.185,0.46,,,,,,,0.712,,45.54,PAH,-1.84567,0.177985,0.00158611,1.06352 kka2_1:8_A9E,kka2_1:8_9,Kka2,kka2_1:8,P00552,1.06352,NO,9,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.079,-3.534,1.455,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.100394,0.00273264,1.06352 kka2_1:8_A9E,kka2_1:8_9,Kka2,kka2_1:8,P00552,1.06352,NO,9,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.079,-3.534,1.455,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.100394,0.00273264,1.06352 beta-lactamase_0_S266D,beta-lactamase_0_266,TEM-1,beta-lactamase_0,P62593,1.06354,NO,266,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.0500837,0.0140785,1.06354 kka2_1:2_T85S,kka2_1:2_85,Kka2,kka2_1:2,P00552,1.06355,NO,85,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.165,-2.241,0.076,,0.576,E,B,0.22,1.39,1.853,,71.59,HPA,-2.10133,0.295029,0.00634493,1.06355 kka2_1:8_D183Q,kka2_1:8_183,Kka2,kka2_1:8,P00552,1.06356,NO,183,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.204,-2.915,1.711,,0.518,.,b,0.75,0.25,0.347,,52.27,AAH,-1.40533,0.100394,0.00426304,1.06356 kka2_1:8_D183Q,kka2_1:8_183,Kka2,kka2_1:8,P00552,1.06356,NO,183,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.204,-2.915,1.711,,0.518,.,b,0.75,0.25,0.347,,52.27,AAH,-1.40533,0.100394,0.00426304,1.06356 kka2_1:8_E161V,kka2_1:8_161,Kka2,kka2_1:8,P00552,1.06359,NO,161,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.581,-2.903,1.322,,0.829,G,A,1.04,2.24,11.923,11.923,92.05,AAB,-1.861,0.100394,0.00760103,1.06359 kka2_1:8_E161V,kka2_1:8_161,Kka2,kka2_1:8,P00552,1.06359,NO,161,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.581,-2.903,1.322,,0.829,G,A,1.04,2.24,11.923,11.923,92.05,AAB,-1.861,0.100394,0.00760103,1.06359 kka2_1:8_Q252L,kka2_1:8_252,Kka2,kka2_1:8,P00552,1.06362,NO,252,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.63,-3.66,1.03,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.100394,0.0121001,1.06362 kka2_1:8_Q252L,kka2_1:8_252,Kka2,kka2_1:8,P00552,1.06362,NO,252,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.63,-3.66,1.03,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.100394,0.0121001,1.06362 kka2_1:8_S68G,kka2_1:8_68,Kka2,kka2_1:8,P00552,1.06362,NO,68,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.623,-2.541,-0.082,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.100394,0.00608265,1.06362 kka2_1:8_S68G,kka2_1:8_68,Kka2,kka2_1:8,P00552,1.06362,NO,68,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.623,-2.541,-0.082,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.100394,0.00608265,1.06362 gb1_E241V,gb1_241,gb1,gb1,P06654,1.06363,NO,241,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.672,-3.09,1.418,,,,,,,0.344,,11.83,OAP,-1.27933,0.177985,0.00250604,1.06363 kka2_1:8_Y22S,kka2_1:8_22,Kka2,kka2_1:8,P00552,1.06363,NO,22,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-1.583,-2.891,1.308,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.100394,0.00598977,1.06363 kka2_1:8_Y22S,kka2_1:8_22,Kka2,kka2_1:8,P00552,1.06363,NO,22,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-1.583,-2.891,1.308,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.100394,0.00598977,1.06363 beta-lactamase_39_I93H,beta-lactamase_39_93,TEM-1,beta-lactamase_39,P62593,1.06365,NO,93,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.401,-5.004,3.603,,0.128,E,B,0.48,0.44,1.757,,67.83,BHB,-1.873,0.0495842,0.00527066,1.06365 beta-lactamase_0_A222V,beta-lactamase_0_222,TEM-1,beta-lactamase_0,P62593,1.06369,NO,222,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.103,-1.973,-0.13,,0.233,H,A,0.46,-0.25,2.015,,77.62,PHH,-1.63733,0.0500837,0.00466094,1.06369 beta-lactamase_0_I140G,beta-lactamase_0_140,TEM-1,beta-lactamase_0,P62593,1.06369,NO,140,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.733,-3.828,2.095,,0.128,H,A,0.48,0.41,4.714,,73.08,PHO,-1.48733,0.0500837,0.00597777,1.06369 kka2_1:4_Q4R,kka2_1:4_4,Kka2,kka2_1:4,P00552,1.06371,NO,4,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.361,-3.443,1.082,,,,,,,2.026,,71.59,APA,-1.95533,0.168804,0.00239179,1.06371 beta-lactamase_0_G234S,beta-lactamase_0_234,TEM-1,beta-lactamase_0,P62593,1.06372,NO,234,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.62,-3.161,2.541,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.0500837,0.000889577,1.06372 beta-lactamase_0_S201V,beta-lactamase_0_201,TEM-1,beta-lactamase_0,P62593,1.06373,NO,201,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.183,-3.482,2.299,,0.064,H,A,0.27,-0.07,3.54,,64.69,HPB,-1.451,0.0500837,0.00198815,1.06373 gb1_D248L,gb1_248,gb1,gb1,P06654,1.06373,NO,248,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.569,-3.369,1.8,,,,,,,0.344,,11.83,HAH,-1.673,0.177985,0.001865,1.06373 beta-lactamase_156_A211Y,beta-lactamase_156_211,TEM-1,beta-lactamase_156,P62593,1.06377,NO,211,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.896,-4.344,2.448,,0.369,T,A,0.46,-0.69,8.527,8.527,77.62,AHA,-1.94633,0.111618,0.00648183,1.06377 beta-lactamase_0_T193F,beta-lactamase_0_193,TEM-1,beta-lactamase_0,P62593,1.06384,NO,193,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.914,-2.368,0.454,,0.439,H,a,0.22,0.33,11.546,11.546,63.99,HPO,-1.52133,0.0500837,0.00482669,1.06384 kka2_1:4_M1I,kka2_1:4_1,Kka2,kka2_1:4,P00552,1.06399,NO,1,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.787,-2.748,0.961,,,,,,,1.347,,62.12,NAHH,-1.787,0.168804,0.00251939,1.06399 kka2_1:8_E59Q,kka2_1:8_59,Kka2,kka2_1:8,P00552,1.06401,NO,59,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-0.952,-2.672,1.72,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.100394,0.00280355,1.06401 kka2_1:8_E59Q,kka2_1:8_59,Kka2,kka2_1:8,P00552,1.06401,NO,59,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-0.952,-2.672,1.72,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.100394,0.00280355,1.06401 beta-lactamase_39_G154M,beta-lactamase_39_154,TEM-1,beta-lactamase_39,P62593,1.06403,NO,154,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.823,-4.936,4.113,,0.54,T,l,0.29,-0.56,1.151,,64.69,HOA,-1.635,0.0495842,0.00180205,1.06403 kka2_1:4_E111K,kka2_1:4_111,Kka2,kka2_1:4,P00552,1.06405,NO,111,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.28,-2.698,0.418,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.168804,0.00746789,1.06405 kka2_1:8_T146K,kka2_1:8_146,Kka2,kka2_1:8,P00552,1.06405,NO,146,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.978,-2.607,-0.371,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.100394,0.00606474,1.06405 kka2_1:8_T146K,kka2_1:8_146,Kka2,kka2_1:8,P00552,1.06405,NO,146,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.978,-2.607,-0.371,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.100394,0.00606474,1.06405 gb1_E245H,gb1_245,gb1,gb1,P06654,1.06406,NO,245,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.725,-4.191,1.466,,,,,,,0.712,,45.54,PAH,-1.84567,0.177985,0.00158611,1.06406 PSD95pdz3_V315K,PSD95pdz3_315,PSD95pdz3,PSD95pdz3,P31016,1.06411,NO,315,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.625,-3.581,1.956,5.52024,,,,,18.4557,4.054,,81.35,HHH,-1.62767,0.0758425,0.00153536,1.06411 kka2_1:8_L57Q,kka2_1:8_57,Kka2,kka2_1:8,P00552,1.06413,NO,57,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.898,-3.254,1.356,,0.343,T,A,0.55,0.98,13.359,13.359,52.65,HHP,-2.20733,0.100394,0.00723769,1.06413 kka2_1:8_L57Q,kka2_1:8_57,Kka2,kka2_1:8,P00552,1.06413,NO,57,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.898,-3.254,1.356,,0.343,T,A,0.55,0.98,13.359,13.359,52.65,HHP,-2.20733,0.100394,0.00723769,1.06413 kka2_1:8_L53D,kka2_1:8_53,Kka2,kka2_1:8,P00552,1.06415,NO,53,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-2.681,-2.935,0.254,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.100394,0.00671168,1.06415 kka2_1:8_L53D,kka2_1:8_53,Kka2,kka2_1:8,P00552,1.06415,NO,53,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-2.681,-2.935,0.254,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.100394,0.00671168,1.06415 kka2_1:2_D33H,kka2_1:2_33,Kka2,kka2_1:2,P00552,1.06416,NO,33,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.186,-4.719,2.533,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.295029,0.00633568,1.06416 kka2_1:8_T125L,kka2_1:8_125,Kka2,kka2_1:8,P00552,1.06416,NO,125,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.622,-3.575,0.953,,0.791,T,A,0.22,0.33,2.675,,92.05,BPH,-1.56933,0.100394,0.00821755,1.06416 kka2_1:8_T125L,kka2_1:8_125,Kka2,kka2_1:8,P00552,1.06416,NO,125,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.622,-3.575,0.953,,0.791,T,A,0.22,0.33,2.675,,92.05,BPH,-1.56933,0.100394,0.00821755,1.06416 beta-lactamase_0_R92C,beta-lactamase_0_92,TEM-1,beta-lactamase_0,P62593,1.06418,NO,92,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.718,-5.119,3.401,,0.479,E,B,1.2,1.36,2.331,,65.38,BBH,-1.50367,0.0500837,0.00429626,1.06418 PSD95pdz3_E334P,PSD95pdz3_334,PSD95pdz3,PSD95pdz3,P31016,1.06421,NO,334,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.404,-3.336,1.932,5.60175,,,,,53.09,,,,OAO,-1.14,0.0758425,0.000912998,1.06421 beta-lactamase_0_V106M,beta-lactamase_0_106,TEM-1,beta-lactamase_0,P62593,1.06427,NO,106,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.218,-3.026,1.808,,0.258,T,A,0.44,0.24,0.952,,72.73,OHP,-1.04933,0.0500837,0.00304168,1.06427 PSD95pdz3_H317N,PSD95pdz3_317,PSD95pdz3,PSD95pdz3,P31016,1.06429,NO,317,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-1.627,-2.905,1.278,6.19713,,,,,25.885,,,,HBB,-1.613,0.0758425,0.00111619,1.06429 PSD95pdz3_A378K,PSD95pdz3_378,PSD95pdz3,PSD95pdz3,P31016,1.0643,NO,378,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.307,-3.139,1.832,4.86582,,,,,14.576,,,,HHH,-1.509,0.0758425,0.000313169,1.0643 PSD95pdz3_L353A,PSD95pdz3_353,PSD95pdz3,PSD95pdz3,P31016,1.06437,NO,353,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.347,-2.759,1.412,5.81136,,,,,17.3525,,,,AHB,-1.50533,0.0758425,0.000664742,1.06437 beta-lactamase_0_N274M,beta-lactamase_0_274,TEM-1,beta-lactamase_0,P62593,1.06439,NO,274,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.0500837,0.0110418,1.06439 E1_Ubiquitin_T68G,E1_Ubiquitin_68,Uba1,E1_Ubiquitin,P0CG63,1.06454,NO,68,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,,,,,,,,,,,,,OPH,-1.039,0.18783,0.00314321,1.06454 beta-lactamase_0_D113I,beta-lactamase_0_113,TEM-1,beta-lactamase_0,P62593,1.06457,NO,113,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.829,-4.028,2.199,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.0500837,0.00474112,1.06457 beta-lactamase_L19A,beta-lactamase_19,TEM-1,beta-lactamase,P62593,1.06459,NO,19,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.682,-3.102,1.42,,,,,,,4.261,,93.01,OHO,-1.894,0.221079,0.00215974,1.06459 kka2_1:2_A255Q,kka2_1:2_255,Kka2,kka2_1:2,P00552,1.06463,NO,255,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.715,-4.01,2.295,,0.466,H,A,0.46,-0.52,5.144,,65.53,HHH,-1.71267,0.295029,0.0126809,1.06463 kka2_1:8_R173G,kka2_1:8_173,Kka2,kka2_1:8,P00552,1.06463,NO,173,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.407,-3.552,1.145,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.100394,0.00784999,1.06463 kka2_1:8_R173G,kka2_1:8_173,Kka2,kka2_1:8,P00552,1.06463,NO,173,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.407,-3.552,1.145,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.100394,0.00784999,1.06463 PSD95pdz3_G322S,PSD95pdz3_322,PSD95pdz3,PSD95pdz3,P31016,1.06463,NO,322,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.008,-2.842,1.834,5.24791,,,,,16.3275,,,,POH,-1.24867,0.0758425,0.00105821,1.06463 kka2_1:4_D156Q,kka2_1:4_156,Kka2,kka2_1:4,P00552,1.06464,NO,156,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.696,-3.891,2.195,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.168804,0.00926998,1.06464 PSD95pdz3_G319S,PSD95pdz3_319,PSD95pdz3,PSD95pdz3,P31016,1.06465,NO,319,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.008,-2.842,1.834,4.95387,,,,,18.8725,,,,BOP,-1.36967,0.0758425,0.00109317,1.06465 beta-lactamase_39_L223M,beta-lactamase_39_223,TEM-1,beta-lactamase_39,P62593,1.06467,NO,223,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.055,-3.986,2.931,,0.27,,B,0.55,0.09,1.511,,74.48,HHO,-1.35033,0.0495842,0.00372793,1.06467 beta-lactamase_0_T269E,beta-lactamase_0_269,TEM-1,beta-lactamase_0,P62593,1.06476,NO,269,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.0500837,0.00950944,1.06476 kka2_1:8_R18P,kka2_1:8_18,Kka2,kka2_1:8,P00552,1.06479,NO,18,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.055,-4.134,2.079,,0.474,T,A,1.2,0.54,19.629,19.629,71.59,ABH,-1.821,0.100394,0.00724065,1.06479 kka2_1:8_R18P,kka2_1:8_18,Kka2,kka2_1:8,P00552,1.06479,NO,18,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.055,-4.134,2.079,,0.474,T,A,1.2,0.54,19.629,19.629,71.59,ABH,-1.821,0.100394,0.00724065,1.06479 beta-lactamase_0_L188D,beta-lactamase_0_188,TEM-1,beta-lactamase_0,P62593,1.06481,NO,188,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.166,-3.967,2.801,,,H,A,0.55,-0.3,2.739,,60.14,PHB,-1.47033,0.0500837,0.00295687,1.06481 kka2_1:4_E96K,kka2_1:4_96,Kka2,kka2_1:4,P00552,1.06484,NO,96,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.573,-3.494,0.921,,0.476,,B,1.52,-0.65,1.254,,71.59,OAH,-2.143,0.168804,0.00369441,1.06484 kka2_1:8_Q27D,kka2_1:8_27,Kka2,kka2_1:8,P00552,1.06485,NO,27,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-1.659,-1.745,0.086,,0.608,.,A,0.64,0.71,3.919,,65.53,PPP,-1.90733,0.100394,0.00595365,1.06485 kka2_1:8_Q27D,kka2_1:8_27,Kka2,kka2_1:8,P00552,1.06485,NO,27,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-1.659,-1.745,0.086,,0.608,.,A,0.64,0.71,3.919,,65.53,PPP,-1.90733,0.100394,0.00595365,1.06485 kka2_1:8_Q42P,kka2_1:8_42,Kka2,kka2_1:8,P00552,1.06485,NO,42,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.907,-2.271,-0.636,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.100394,0.00679212,1.06485 kka2_1:8_Q42P,kka2_1:8_42,Kka2,kka2_1:8,P00552,1.06485,NO,42,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.907,-2.271,-0.636,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.100394,0.00679212,1.06485 kka2_1:8_Y257F,kka2_1:8_257,Kka2,kka2_1:8,P00552,1.0649,NO,257,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-1.064,-1.664,0.6,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.100394,0.0148191,1.0649 kka2_1:8_Y257F,kka2_1:8_257,Kka2,kka2_1:8,P00552,1.0649,NO,257,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-1.064,-1.664,0.6,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.100394,0.0148191,1.0649 gb1_Q258G,gb1_258,gb1,gb1,P06654,1.06492,NO,258,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.095,-2.979,0.884,,,,,,,0.86,,37.28,BPH,-1.88333,0.177985,0.00437595,1.06492 beta-lactamase_39_E26V,beta-lactamase_39_26,TEM-1,beta-lactamase_39,P62593,1.06501,NO,26,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.454,-2.776,0.322,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.0495842,0.00297948,1.06501 WW_domain_Q200N,WW_domain_200,Yap65,WW_domain,P46937,1.06502,NO,200,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-1.599,-3.336,1.737,5.37476,,,,,,1.9,,70.04,HPA,-1.484,0.153962,0.00300397,1.06502 beta-lactamase_625_E26G,beta-lactamase_625_26,TEM-1,beta-lactamase_625,P62593,1.06503,NO,26,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.454,-2.639,0.185,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.213352,0.00297948,1.06503 kka2_1:2_A168V,kka2_1:2_168,Kka2,kka2_1:2,P00552,1.06503,NO,168,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.989,-3.131,1.142,,0.67,H,A,0.46,0.15,25.546,25.546,64.39,OHA,-2.12933,0.295029,0.00806773,1.06503 kka2_1:4_L94C,kka2_1:4_94,Kka2,kka2_1:4,P00552,1.06503,NO,94,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.618,-4.788,3.17,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.168804,0.00520888,1.06503 kka2_1:8_A166P,kka2_1:8_166,Kka2,kka2_1:8,P00552,1.06506,NO,166,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.407,-2.34,-0.067,,0.534,,B,1.04,1.03,13.995,13.995,71.59,HHO,-2.421,0.100394,0.00799912,1.06506 kka2_1:8_A166P,kka2_1:8_166,Kka2,kka2_1:8,P00552,1.06506,NO,166,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.407,-2.34,-0.067,,0.534,,B,1.04,1.03,13.995,13.995,71.59,HHO,-2.421,0.100394,0.00799912,1.06506 beta-lactamase_0_I285Q,beta-lactamase_0_285,TEM-1,beta-lactamase_0,P62593,1.06508,NO,285,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.0500837,0.101555,1.06508 beta-lactamase_0_R275A,beta-lactamase_0_275,TEM-1,beta-lactamase_0,P62593,1.06508,NO,275,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.0500837,0.0141984,1.06508 beta-lactamase_L19Q,beta-lactamase_19,TEM-1,beta-lactamase,P62593,1.06511,NO,19,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.682,-2.842,1.16,,,,,,,4.261,,93.01,OHO,-1.894,0.221079,0.00215974,1.06511 kka2_1:4_E59Q,kka2_1:4_59,Kka2,kka2_1:4,P00552,1.06511,NO,59,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-0.952,-2.672,1.72,,0.187,.,L,1.04,0.62,3.408,,50.38,PAH,-1.53,0.168804,0.00280355,1.06511 kka2_1:8_D118L,kka2_1:8_118,Kka2,kka2_1:8,P00552,1.06516,NO,118,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.07,-3.589,1.519,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.100394,0.0067852,1.06516 kka2_1:8_D118L,kka2_1:8_118,Kka2,kka2_1:8,P00552,1.06516,NO,118,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.07,-3.589,1.519,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.100394,0.0067852,1.06516 kka2_1:8_V80Q,kka2_1:8_80,Kka2,kka2_1:8,P00552,1.06522,NO,80,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.144,-4.244,3.1,,0.358,E,B,1.48,-0.24,2.562,,63.64,HHH,-1.64633,0.100394,0.00488211,1.06522 kka2_1:8_V80Q,kka2_1:8_80,Kka2,kka2_1:8,P00552,1.06522,NO,80,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.144,-4.244,3.1,,0.358,E,B,1.48,-0.24,2.562,,63.64,HHH,-1.64633,0.100394,0.00488211,1.06522 beta-lactamase_39_P25K,beta-lactamase_39_25,TEM-1,beta-lactamase_39,P62593,1.06527,NO,25,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.526,-3.426,1.9,,0.624,H,A,0.52,0.14,1.157,,73.08,BOA,-2.15367,0.0495842,0.00347571,1.06527 kka2_1:2_L7N,kka2_1:2_7,Kka2,kka2_1:2,P00552,1.06528,NO,7,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.926,-3.49,1.564,,,,,,,3.012,,71.59,OHB,-2.12333,0.295029,0.00269456,1.06528 beta-lactamase_39_T187W,beta-lactamase_39_187,TEM-1,beta-lactamase_39,P62593,1.06529,NO,187,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.401,-5.371,3.97,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.0495842,0.00491782,1.06529 kka2_1:8_E231G,kka2_1:8_231,Kka2,kka2_1:8,P00552,1.0653,NO,231,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.002,-3.247,1.245,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.100394,0.00732383,1.0653 kka2_1:8_E231G,kka2_1:8_231,Kka2,kka2_1:8,P00552,1.0653,NO,231,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.002,-3.247,1.245,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.100394,0.00732383,1.0653 kka2_1:8_S68N,kka2_1:8_68,Kka2,kka2_1:8,P00552,1.0653,NO,68,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.623,-3.062,0.439,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.100394,0.00608265,1.0653 kka2_1:8_S68N,kka2_1:8_68,Kka2,kka2_1:8,P00552,1.0653,NO,68,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.623,-3.062,0.439,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.100394,0.00608265,1.0653 beta-lactamase_0_E102T,beta-lactamase_0_102,TEM-1,beta-lactamase_0,P62593,1.06533,NO,102,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.118,-2.156,0.038,,0.722,S,B,1.04,1.82,4.773,,73.08,HAH,-1.581,0.0500837,0.00486633,1.06533 kka2_1:8_A64N,kka2_1:8_64,Kka2,kka2_1:8,P00552,1.06536,NO,64,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.496,-4.101,2.605,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.100394,0.00705578,1.06536 kka2_1:8_A64N,kka2_1:8_64,Kka2,kka2_1:8,P00552,1.06536,NO,64,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.496,-4.101,2.605,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.100394,0.00705578,1.06536 PSD95pdz3_A382Q,PSD95pdz3_382,PSD95pdz3,PSD95pdz3,P31016,1.06537,NO,382,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.307,-3.581,2.274,5.30282,,,,,22.472,,,,PHO,-1.24167,0.0758425,0.000249256,1.06537 PSD95pdz3_I389A,PSD95pdz3_389,PSD95pdz3,PSD95pdz3,P31016,1.06539,NO,389,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.628,-2.758,1.13,5.15116,,,,,14.8038,1.498,,87.71,HHH,-1.52167,0.0758425,0.00148097,1.06539 beta-lactamase_0_G216R,beta-lactamase_0_216,TEM-1,beta-lactamase_0,P62593,1.06542,NO,216,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.477,-2.93,1.453,,0.437,I,A,0.29,-0.58,0.834,,74.48,HOO,-1.68067,0.0500837,0.00639568,1.06542 kka2_1:8_P167Q,kka2_1:8_167,Kka2,kka2_1:8,P00552,1.06542,NO,167,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-2.403,-4.147,1.744,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.100394,0.00543203,1.06542 kka2_1:8_P167Q,kka2_1:8_167,Kka2,kka2_1:8,P00552,1.06542,NO,167,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-2.403,-4.147,1.744,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.100394,0.00543203,1.06542 PSD95pdz3_G333V,PSD95pdz3_333,PSD95pdz3,PSD95pdz3,P31016,1.06545,NO,333,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.008,-3.435,2.427,5.09445,,,,,48.755,,,,AOA,-1.22533,0.0758425,0.00092544,1.06545 kka2_1:8_Q42G,kka2_1:8_42,Kka2,kka2_1:8,P00552,1.06548,NO,42,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.907,-2.492,-0.415,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.100394,0.00679212,1.06548 kka2_1:8_Q42G,kka2_1:8_42,Kka2,kka2_1:8,P00552,1.06548,NO,42,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.907,-2.492,-0.415,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.100394,0.00679212,1.06548 PSD95pdz3_Y392Q,PSD95pdz3_392,PSD95pdz3,PSD95pdz3,P31016,1.06551,NO,392,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-1.437,-3.581,2.144,5.20337,,,,,11.725,,,,PHB,-1.51733,0.0758425,0.000935211,1.06551 beta-lactamase_39_H110K,beta-lactamase_39_110,TEM-1,beta-lactamase_39,P62593,1.06553,NO,110,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-1.706,-2.755,1.049,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.0495842,0.00441499,1.06553 Pab1_P200G,Pab1_200,Pab1,Pab1,P04147,1.06565,NO,200,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.871,-3.388,1.517,,,,,,,3.877,,80.59,HOO,-1.7005,0.175299,0.00190795,1.06565 kka2_1:8_E230W,kka2_1:8_230,Kka2,kka2_1:8,P00552,1.06568,NO,230,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.672,-5.201,2.529,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.100394,0.00920051,1.06568 kka2_1:8_E230W,kka2_1:8_230,Kka2,kka2_1:8,P00552,1.06568,NO,230,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.672,-5.201,2.529,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.100394,0.00920051,1.06568 PSD95pdz3_I389T,PSD95pdz3_389,PSD95pdz3,PSD95pdz3,P31016,1.06568,NO,389,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.628,-3.102,1.474,5.15116,,,,,14.8038,1.498,,87.71,HHH,-1.52167,0.0758425,0.00148097,1.06568 beta-lactamase_0_L137F,beta-lactamase_0_137,TEM-1,beta-lactamase_0,P62593,1.0657,NO,137,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.03,-3.682,2.652,,,H,A,0.55,-0.38,0.328,,42.31,HHP,-1.58933,0.0500837,0.00278599,1.0657 PSD95pdz3_T321L,PSD95pdz3_321,PSD95pdz3,PSD95pdz3,P31016,1.0657,NO,321,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.391,-2.815,1.424,5.19953,,,,,20.3371,,,,PPO,-1.306,0.0758425,0.00106992,1.0657 kka2_1:2_S40M,kka2_1:2_40,Kka2,kka2_1:2,P00552,1.06573,NO,40,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.645,-4.831,2.186,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.295029,0.00693477,1.06573 beta-lactamase_0_D33H,beta-lactamase_0_33,TEM-1,beta-lactamase_0,P62593,1.06574,NO,33,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.321,-4.654,2.333,,0.366,H,A,0.75,0.33,12.514,12.514,77.62,BAH,-2.12133,0.0500837,0.00435556,1.06574 beta-lactamase_0_Y44Q,beta-lactamase_0_44,TEM-1,beta-lactamase_0,P62593,1.0658,NO,44,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-2.547,-4.196,1.649,,,E,B,0.21,-0.45,1.751,,73.78,OHH,-1.86267,0.0500837,0.00426364,1.0658 beta-lactamase_39_D212C,beta-lactamase_39_212,TEM-1,beta-lactamase_39,P62593,1.0658,NO,212,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.624,-5.061,3.437,,0.037,,b,0.75,-0.58,10.748,10.748,74.48,HAB,-1.77667,0.0495842,0.00644302,1.0658 kka2_1:8_H139D,kka2_1:8_139,Kka2,kka2_1:8,P00552,1.06581,NO,139,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-2.809,-3.251,0.442,,0.471,H,A,0.17,0.68,28.583,28.583,63.64,BBB,-2.22,0.100394,0.00734779,1.06581 kka2_1:8_H139D,kka2_1:8_139,Kka2,kka2_1:8,P00552,1.06581,NO,139,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-2.809,-3.251,0.442,,0.471,H,A,0.17,0.68,28.583,28.583,63.64,BBB,-2.22,0.100394,0.00734779,1.06581 kka2_1:4_A25C,kka2_1:4_25,Kka2,kka2_1:4,P00552,1.06583,NO,25,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.496,-5.199,2.703,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.168804,0.00595636,1.06583 beta-lactamase_0_A222S,beta-lactamase_0_222,TEM-1,beta-lactamase_0,P62593,1.06585,NO,222,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.103,-2.253,0.15,,0.233,H,A,0.46,-0.25,2.015,,77.62,PHH,-1.63733,0.0500837,0.00466094,1.06585 beta-lactamase_0_P172Q,beta-lactamase_0_172,TEM-1,beta-lactamase_0,P62593,1.06585,NO,172,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-0.998,-3.965,2.967,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.0500837,0.00312594,1.06585 kka2_1:2_W15F,kka2_1:2_15,Kka2,kka2_1:2,P00552,1.06586,NO,15,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-1.392,-2.518,1.126,,0.01,G,A,0.47,0.15,2.586,,52.27,HHH,-2.10533,0.295029,0.00585505,1.06586 kka2_1:8_F37L,kka2_1:8_37,Kka2,kka2_1:8,P00552,1.06586,NO,37,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.427,-2.514,1.087,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.100394,0.00586193,1.06586 kka2_1:8_F37L,kka2_1:8_37,Kka2,kka2_1:8,P00552,1.06586,NO,37,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.427,-2.514,1.087,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.100394,0.00586193,1.06586 kka2_1:8_V185C,kka2_1:8_185,Kka2,kka2_1:8,P00552,1.06588,NO,185,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.045,-3.114,2.069,,0.058,E,B,1.48,-0.49,1.234,,46.97,HHH,-1.184,0.100394,0.00367031,1.06588 kka2_1:8_V185C,kka2_1:8_185,Kka2,kka2_1:8,P00552,1.06588,NO,185,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.045,-3.114,2.069,,0.058,E,B,1.48,-0.49,1.234,,46.97,HHH,-1.184,0.100394,0.00367031,1.06588 beta-lactamase_39_F58C,beta-lactamase_39_58,TEM-1,beta-lactamase_39,P62593,1.06589,NO,58,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-2.914,-5.093,2.179,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.0495842,0.00523369,1.06589 gb1_D262C,gb1_262,gb1,gb1,P06654,1.06589,NO,262,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-3.132,-4.702,1.57,,,,,,,1.304,,45.54,PAP,-2.05233,0.177985,0.00413102,1.06589 PSD95pdz3_G319F,PSD95pdz3_319,PSD95pdz3,PSD95pdz3,P31016,1.06595,NO,319,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.008,-3.974,2.966,4.95387,,,,,18.8725,,,,BOP,-1.36967,0.0758425,0.00109317,1.06595 kka2_1:8_E3G,kka2_1:8_3,Kka2,kka2_1:8,P00552,1.06596,NO,3,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.199,-2.062,-0.137,,,,,,,7.22,,92.05,HAP,-2.11567,0.100394,0.00267607,1.06596 kka2_1:8_E3G,kka2_1:8_3,Kka2,kka2_1:8,P00552,1.06596,NO,3,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.199,-2.062,-0.137,,,,,,,7.22,,92.05,HAP,-2.11567,0.100394,0.00267607,1.06596 WW_domain_Q186R,WW_domain_186,Yap65,WW_domain,P46937,1.06597,NO,186,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-1.358,-3.035,1.677,4.88854,,,,,,,,,OPB,-1.207,0.153962,0.00161546,1.06597 gb1_E245N,gb1_245,gb1,gb1,P06654,1.06599,NO,245,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.725,-3.183,0.458,,,,,,,0.712,,45.54,PAH,-1.84567,0.177985,0.00158611,1.06599 kka2_1:1_L53R,kka2_1:1_53,Kka2,kka2_1:1,P00552,1.06603,NO,53,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-2.681,-2.891,0.21,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.520039,0.00671168,1.06603 kka2_1:8_L241M,kka2_1:8_241,Kka2,kka2_1:8,P00552,1.06606,NO,241,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.158,-4.084,2.926,,0.08,H,A,1.59,-0.82,1.136,,63.26,HHH,-1.58533,0.100394,0.0117299,1.06606 kka2_1:8_L241M,kka2_1:8_241,Kka2,kka2_1:8,P00552,1.06606,NO,241,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.158,-4.084,2.926,,0.08,H,A,1.59,-0.82,1.136,,63.26,HHH,-1.58533,0.100394,0.0117299,1.06606 PSD95pdz3_Q391Y,PSD95pdz3_391,PSD95pdz3,PSD95pdz3,P31016,1.06617,NO,391,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-1.699,-3.619,1.92,5.50275,,,,,12.6589,,,,HPH,-1.481,0.0758425,0.000990786,1.06617 beta-lactamase_39_I171R,beta-lactamase_39_171,TEM-1,beta-lactamase_39,P62593,1.0662,NO,171,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-2.431,-2.473,0.042,,0.361,,B,0.48,0.53,16.954,16.954,77.62,HHO,-1.55533,0.0495842,0.00623355,1.0662 beta-lactamase_625_V29M,beta-lactamase_625_29,TEM-1,beta-lactamase_625,P62593,1.06621,NO,29,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-2.856,-4.721,1.865,,0.733,H,A,0.44,-0.78,1.931,,93.01,HHB,-2.24733,0.213352,0.00318969,1.06621 beta-lactamase_0_G216P,beta-lactamase_0_216,TEM-1,beta-lactamase_0,P62593,1.06624,NO,216,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.477,-3.898,2.421,,0.437,I,A,0.29,-0.58,0.834,,74.48,HOO,-1.68067,0.0500837,0.00639568,1.06624 beta-lactamase_0_A246T,beta-lactamase_0_246,TEM-1,beta-lactamase_0,P62593,1.06625,NO,246,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.121,-3.507,1.386,,0.01,E,B,0.46,-1.01,1.201,,73.78,HHH,-1.55633,0.0500837,0.00569458,1.06625 beta-lactamase_39_A211M,beta-lactamase_39_211,TEM-1,beta-lactamase_39,P62593,1.06625,NO,211,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.896,-3.437,1.541,,0.369,T,A,0.46,-0.69,1.419,,77.62,AHA,-1.94633,0.0495842,0.00648183,1.06625 PSD95pdz3_I389N,PSD95pdz3_389,PSD95pdz3,PSD95pdz3,P31016,1.06625,NO,389,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.628,-3.9,2.272,5.15116,,,,,14.8038,1.498,,87.71,HHH,-1.52167,0.0758425,0.00148097,1.06625 E1_Ubiquitin_Q41W,E1_Ubiquitin_41,Uba1,E1_Ubiquitin,P0CG63,1.06631,NO,41,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-1.25,-4.915,3.665,,0.017,E,B,,-0.98,,,,PPB,-1.344,0.18783,0.00215097,1.06631 E1_Ubiquitin_R74H,E1_Ubiquitin_74,Uba1,E1_Ubiquitin,P0CG63,1.06631,NO,74,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.302,-4.151,2.849,,0.838,T,A,,3.15,,,,HBO,-1.11333,0.18783,0.00180798,1.06631 beta-lactamase_625_V106C,beta-lactamase_625_106,TEM-1,beta-lactamase_625,P62593,1.06632,NO,106,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.218,-4.774,3.556,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.213352,0.00304168,1.06632 kka2_1:8_V83E,kka2_1:8_83,Kka2,kka2_1:8,P00552,1.06633,NO,83,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-2.567,-2.291,-0.276,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.100394,0.00650486,1.06633 kka2_1:8_V83E,kka2_1:8_83,Kka2,kka2_1:8,P00552,1.06633,NO,83,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-2.567,-2.291,-0.276,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.100394,0.00650486,1.06633 beta-lactamase_0_T27C,beta-lactamase_0_27,TEM-1,beta-lactamase_0,P62593,1.06635,NO,27,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.905,-4.927,3.022,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.0500837,0.00306559,1.06635 kka2_1:4_Q252F,kka2_1:4_252,Kka2,kka2_1:4,P00552,1.06635,NO,252,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.63,-4.468,1.838,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.168804,0.0121001,1.06635 beta-lactamase_0_S221C,beta-lactamase_0_221,TEM-1,beta-lactamase_0,P62593,1.06637,NO,221,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.754,-3.097,1.343,,0.624,H,A,0.27,-0.2,2.914,,74.48,BPH,-1.59967,0.0500837,0.0046094,1.06637 beta-lactamase_0_R275G,beta-lactamase_0_275,TEM-1,beta-lactamase_0,P62593,1.06638,NO,275,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.0500837,0.0141984,1.06638 gb1_T251I,gb1_251,gb1,gb1,P06654,1.06642,NO,251,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.794,-3.22,1.426,,,,,,,3.514,3.514,37.28,HPH,-1.56067,0.177985,0.00232932,1.06642 kka2_1:8_A117V,kka2_1:8_117,Kka2,kka2_1:8,P00552,1.06642,NO,117,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.828,-2.25,1.422,,,H,A,1.04,-0.78,0.755,,45.83,HHA,-1.79333,0.100394,0.00282984,1.06642 kka2_1:8_A117V,kka2_1:8_117,Kka2,kka2_1:8,P00552,1.06642,NO,117,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.828,-2.25,1.422,,,H,A,1.04,-0.78,0.755,,45.83,HHA,-1.79333,0.100394,0.00282984,1.06642 PSD95pdz3_G344L,PSD95pdz3_344,PSD95pdz3,PSD95pdz3,P31016,1.06642,NO,344,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.008,-3.49,2.482,4.83855,,,,,14.06,,,,HOO,-1.10767,0.0758425,0.00078498,1.06642 beta-lactamase_0_A170T,beta-lactamase_0_170,TEM-1,beta-lactamase_0,P62593,1.06643,NO,170,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.237,-3.423,2.186,,0.126,,L,0.46,-0.35,2.427,,64.69,AHH,-1.63267,0.0500837,0.00431903,1.06643 beta-lactamase_0_V106D,beta-lactamase_0_106,TEM-1,beta-lactamase_0,P62593,1.06649,NO,106,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.218,-4.056,2.838,,0.258,T,A,0.44,0.24,0.952,,72.73,OHP,-1.04933,0.0500837,0.00304168,1.06649 PSD95pdz3_S320P,PSD95pdz3_320,PSD95pdz3,PSD95pdz3,P31016,1.06653,NO,320,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.519,-3.336,1.817,5.81757,,,,,21.4517,,,,OPP,-1.306,0.0758425,0.00108158,1.06653 PSD95pdz3_T387K,PSD95pdz3_387,PSD95pdz3,PSD95pdz3,P31016,1.06657,NO,387,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.391,-3.139,1.748,5.20757,,,,,18.8043,,,,HPH,-1.49533,0.0758425,0.000167911,1.06657 PSD95pdz3_D357M,PSD95pdz3_357,PSD95pdz3,PSD95pdz3,P31016,1.06659,NO,357,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.264,-4.612,3.348,5.22306,,,,,10.975,,,,OAP,-1.32367,0.0758425,0.000609015,1.06659 beta-lactamase_39_W208I,beta-lactamase_39_208,TEM-1,beta-lactamase_39,P62593,1.06662,NO,208,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-0.818,-4.01,3.192,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.0495842,0.00126609,1.06662 kka2_1:8_A34G,kka2_1:8_34,Kka2,kka2_1:8,P00552,1.06662,NO,34,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.928,-2.969,2.041,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.100394,0.00343484,1.06662 kka2_1:8_A34G,kka2_1:8_34,Kka2,kka2_1:8,P00552,1.06662,NO,34,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.928,-2.969,2.041,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.100394,0.00343484,1.06662 kka2_1:8_V214I,kka2_1:8_214,Kka2,kka2_1:8,P00552,1.06662,NO,214,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.261,-1.849,0.588,,0.117,E,B,1.48,-0.31,1.859,,64.39,OHH,-0.941667,0.100394,0.00692782,1.06662 kka2_1:8_V214I,kka2_1:8_214,Kka2,kka2_1:8,P00552,1.06662,NO,214,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.261,-1.849,0.588,,0.117,E,B,1.48,-0.31,1.859,,64.39,OHH,-0.941667,0.100394,0.00692782,1.06662 kka2_1:8_Q100Y,kka2_1:8_100,Kka2,kka2_1:8,P00552,1.06665,NO,100,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.77,-4.334,1.564,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.100394,0.0066405,1.06665 kka2_1:8_Q100Y,kka2_1:8_100,Kka2,kka2_1:8,P00552,1.06665,NO,100,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.77,-4.334,1.564,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.100394,0.0066405,1.06665 kka2_1:8_V83M,kka2_1:8_83,Kka2,kka2_1:8,P00552,1.06667,NO,83,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-2.567,-3.575,1.008,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.100394,0.00650486,1.06667 kka2_1:8_V83M,kka2_1:8_83,Kka2,kka2_1:8,P00552,1.06667,NO,83,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-2.567,-3.575,1.008,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.100394,0.00650486,1.06667 beta-lactamase_39_R92H,beta-lactamase_39_92,TEM-1,beta-lactamase_39,P62593,1.06673,NO,92,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.718,-4.618,2.9,,0.479,E,B,1.2,1.36,0.389,,65.38,BBH,-1.50367,0.0495842,0.00429626,1.06673 PSD95pdz3_L323M,PSD95pdz3_323,PSD95pdz3,PSD95pdz3,P31016,1.06673,NO,323,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.347,-3.487,2.14,5.12397,,,,,13.8825,,,,OHO,-1.121,0.0758425,0.00104644,1.06673 kka2_1:8_S251R,kka2_1:8_251,Kka2,kka2_1:8,P00552,1.06675,NO,251,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.636,-2.795,0.159,,0.712,H,A,0.27,-0.25,,,71.59,APP,-2.09367,0.100394,0.0138916,1.06675 kka2_1:8_S251R,kka2_1:8_251,Kka2,kka2_1:8,P00552,1.06675,NO,251,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.636,-2.795,0.159,,0.712,H,A,0.27,-0.25,,,71.59,APP,-2.09367,0.100394,0.0138916,1.06675 PSD95pdz3_P311S,PSD95pdz3_311,PSD95pdz3,PSD95pdz3,P31016,1.06679,NO,311,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.236,-3.067,1.831,5.76649,,,,,14.78,,,,OOB,-1.409,0.0758425,0.0030796,1.06679 gb1_D273T,gb1_273,gb1,gb1,P06654,1.06684,NO,273,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.998,-3.264,1.266,,,,,,,3.514,3.514,37.28,AAH,-1.72767,0.177985,0.00318903,1.06684 kka2_1:4_Q100R,kka2_1:4_100,Kka2,kka2_1:4,P00552,1.06686,NO,100,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.77,-2.202,-0.568,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.168804,0.0066405,1.06686 beta-lactamase_0_K286S,beta-lactamase_0_286,TEM-1,beta-lactamase_0,P62593,1.06692,NO,286,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.0500837,,1.06692 kka2_1:8_D134E,kka2_1:8_134,Kka2,kka2_1:8,P00552,1.06692,NO,134,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.969,-2.461,1.492,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.100394,0.00270812,1.06692 kka2_1:8_D134E,kka2_1:8_134,Kka2,kka2_1:8,P00552,1.06692,NO,134,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.969,-2.461,1.492,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.100394,0.00270812,1.06692 kka2_1:8_Q136D,kka2_1:8_136,Kka2,kka2_1:8,P00552,1.06693,NO,136,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-3.021,-3.719,0.698,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.100394,0.00624149,1.06693 kka2_1:8_Q136D,kka2_1:8_136,Kka2,kka2_1:8,P00552,1.06693,NO,136,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-3.021,-3.719,0.698,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.100394,0.00624149,1.06693 kka2_1:4_P179M,kka2_1:4_179,Kka2,kka2_1:4,P00552,1.06698,NO,179,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.974,-4.581,3.607,,0.113,,B,0.52,0.69,10.913,10.913,56.06,HOA,-2.19867,0.168804,0.00298346,1.06698 PSD95pdz3_S320A,PSD95pdz3_320,PSD95pdz3,PSD95pdz3,P31016,1.06702,NO,320,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.519,-2.309,0.79,5.81757,,,,,21.4517,,,,OPP,-1.306,0.0758425,0.00108158,1.06702 beta-lactamase_A148M,beta-lactamase_148,TEM-1,beta-lactamase,P62593,1.06703,NO,148,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.757,-4.798,3.041,5.28111,0.379,H,A,0.52,-0.55,2.117,,72.73,PHH,-1.40167,0.221079,0.00547053,1.06703 beta-lactamase_A16M,beta-lactamase_16,TEM-1,beta-lactamase,P62593,1.06703,NO,16,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,,-4.573,2.638,,,,,,,,,,HHH,,0.221079,0.00245392,1.06703 beta-lactamase_A182M,beta-lactamase_182,TEM-1,beta-lactamase,P62593,1.06703,NO,182,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.777,-4.709,2.932,4.98609,0.136,H,A,0.52,-0.66,2.032,,93.01,OHH,-1.27367,0.221079,0.00559099,1.06703 beta-lactamase_K109Y,beta-lactamase_109,TEM-1,beta-lactamase,P62593,1.06703,NO,109,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.734,-4.334,2.6,6.05842,0.787,G,A,1.82,2.21,21.623,21.623,72.73,ABB,-1.63333,0.221079,0.00462493,1.06703 beta-lactamase_L196N,beta-lactamase_196,TEM-1,beta-lactamase,P62593,1.06703,NO,196,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-2.478,-3.953,1.475,,0.518,S,A,0.55,1.35,,,77.62,AHH,-1.839,0.221079,0.00512144,1.06703 beta-lactamase_N98Q,beta-lactamase_98,TEM-1,beta-lactamase,P62593,1.06703,NO,98,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-2.973,-2.336,-0.637,6.59973,0.963,G,A,1.07,1.35,1.332,,77.62,PPA,-2.07867,0.221079,0.00505389,1.06703 beta-lactamase_S281F,beta-lactamase_281,TEM-1,beta-lactamase,P62593,1.06703,NO,281,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.247,-4.062,1.815,4.73591,0.128,H,A,0.25,-0.26,2.144,,77.62,HPH,-1.847,0.221079,0.0406482,1.06703 beta-lactamase_S51D,beta-lactamase_51,TEM-1,beta-lactamase,P62593,1.06703,NO,51,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.526,-2.756,1.23,5.06164,0.496,T,A,0.25,0.26,1.699,,72.73,PPO,-1.88467,0.221079,0.00504821,1.06703 beta-lactamase_T186C,beta-lactamase_186,TEM-1,beta-lactamase,P62593,1.06703,NO,186,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.522,-5.021,2.499,5.07364,0.396,H,A,0.3,-0.28,2.144,,77.62,HPP,-1.77633,0.221079,0.00485034,1.06703 beta-lactamase_T186W,beta-lactamase_186,TEM-1,beta-lactamase,P62593,1.06703,NO,186,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.522,-5.446,2.924,5.07364,0.396,H,A,0.3,-0.28,2.144,,77.62,HPP,-1.77633,0.221079,0.00485034,1.06703 beta-lactamase_V157K,beta-lactamase_157,TEM-1,beta-lactamase,P62593,1.06703,NO,157,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.751,-2.698,0.947,5.51733,0.308,S,a,0.96,-0.75,1.847,,69.58,BHP,-2.00767,0.221079,0.00506849,1.06703 beta-lactamase_0_R242H,beta-lactamase_0_242,TEM-1,beta-lactamase_0,P62593,1.06704,NO,242,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.0500837,0.00452879,1.06704 kka2_1:8_K138F,kka2_1:8_138,Kka2,kka2_1:8,P00552,1.06705,NO,138,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-2.5,-4.458,1.958,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.100394,0.00628542,1.06705 kka2_1:8_K138F,kka2_1:8_138,Kka2,kka2_1:8,P00552,1.06705,NO,138,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-2.5,-4.458,1.958,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.100394,0.00628542,1.06705 kka2_1:8_D33N,kka2_1:8_33,Kka2,kka2_1:8,P00552,1.06706,NO,33,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.186,-2.693,0.507,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.100394,0.00633568,1.06706 kka2_1:8_D33N,kka2_1:8_33,Kka2,kka2_1:8,P00552,1.06706,NO,33,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.186,-2.693,0.507,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.100394,0.00633568,1.06706 kka2_1:8_S104L,kka2_1:8_104,Kka2,kka2_1:8,P00552,1.06706,NO,104,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.436,-3.504,2.068,,0.536,T,A,0.27,-1.11,1.689,,63.64,HPP,-1.91433,0.100394,0.00555207,1.06706 kka2_1:8_S104L,kka2_1:8_104,Kka2,kka2_1:8,P00552,1.06706,NO,104,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.436,-3.504,2.068,,0.536,T,A,0.27,-1.11,1.689,,63.64,HPP,-1.91433,0.100394,0.00555207,1.06706 beta-lactamase_39_G253K,beta-lactamase_39_253,TEM-1,beta-lactamase_39,P62593,1.06712,NO,253,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.0495842,0.00786358,1.06712 gb1_Q228A,gb1_228,gb1,gb1,P06654,1.06716,NO,228,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,,,,,,,,,,,,,OPH,-1.282,0.177985,0.00391043,1.06716 kka2_1:8_Q4Y,kka2_1:8_4,Kka2,kka2_1:8,P00552,1.06721,NO,4,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.361,-4.04,1.679,,,,,,,2.026,,71.59,APA,-1.95533,0.100394,0.00239179,1.06721 kka2_1:8_Q4Y,kka2_1:8_4,Kka2,kka2_1:8,P00552,1.06721,NO,4,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.361,-4.04,1.679,,,,,,,2.026,,71.59,APA,-1.95533,0.100394,0.00239179,1.06721 beta-lactamase_39_V106L,beta-lactamase_39_106,TEM-1,beta-lactamase_39,P62593,1.06725,NO,106,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.218,-2.154,0.936,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.0495842,0.00304168,1.06725 kka2_1:2_E169Q,kka2_1:2_169,Kka2,kka2_1:2,P00552,1.06729,NO,169,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.996,-2.511,0.515,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.295029,0.00730086,1.06729 kka2_1:4_D134G,kka2_1:4_134,Kka2,kka2_1:4,P00552,1.06729,NO,134,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.969,-3.259,2.29,,0.421,B,B,0.75,0.31,0.733,,49.62,HAB,-1.057,0.168804,0.00270812,1.06729 kka2_1:4_P76R,kka2_1:4_76,Kka2,kka2_1:4,P00552,1.0673,NO,76,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.449,-4.026,2.577,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.168804,0.00625685,1.0673 kka2_1:8_G95A,kka2_1:8_95,Kka2,kka2_1:8,P00552,1.0673,NO,95,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-2.403,-3.101,0.698,,0.126,E,B,0.75,-0.74,7.774,,71.59,HOA,-2.198,0.100394,0.00743616,1.0673 kka2_1:8_G95A,kka2_1:8_95,Kka2,kka2_1:8,P00552,1.0673,NO,95,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-2.403,-3.101,0.698,,0.126,E,B,0.75,-0.74,7.774,,71.59,HOA,-2.198,0.100394,0.00743616,1.0673 kka2_1:8_H139P,kka2_1:8_139,Kka2,kka2_1:8,P00552,1.06736,NO,139,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-2.809,-4.177,1.368,,0.471,H,A,0.17,0.68,28.583,28.583,63.64,BBB,-2.22,0.100394,0.00734779,1.06736 kka2_1:8_H139P,kka2_1:8_139,Kka2,kka2_1:8,P00552,1.06736,NO,139,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-2.809,-4.177,1.368,,0.471,H,A,0.17,0.68,28.583,28.583,63.64,BBB,-2.22,0.100394,0.00734779,1.06736 kka2_1:8_G43M,kka2_1:8_43,Kka2,kka2_1:8,P00552,1.06742,NO,43,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.587,-4.94,3.353,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.100394,0.0071925,1.06742 kka2_1:8_G43M,kka2_1:8_43,Kka2,kka2_1:8,P00552,1.06742,NO,43,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.587,-4.94,3.353,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.100394,0.0071925,1.06742 beta-lactamase_39_W208C,beta-lactamase_39_208,TEM-1,beta-lactamase_39,P62593,1.06748,NO,208,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,-0.818,-4.862,4.044,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.0495842,0.00126609,1.06748 gb1_D273L,gb1_273,gb1,gb1,P06654,1.06748,NO,273,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.998,-3.433,1.435,,,,,,,3.514,3.514,37.28,AAH,-1.72767,0.177985,0.00318903,1.06748 beta-lactamase_156_M127D,beta-lactamase_156_127,TEM-1,beta-lactamase_156,P62593,1.06749,NO,127,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-2.251,-3.966,1.715,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.111618,0.00437927,1.06749 beta-lactamase_0_A222P,beta-lactamase_0_222,TEM-1,beta-lactamase_0,P62593,1.0675,NO,222,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.103,-2.971,0.868,,0.233,H,A,0.46,-0.25,2.015,,77.62,PHH,-1.63733,0.0500837,0.00466094,1.0675 kka2_1:4_G10V,kka2_1:4_10,Kka2,kka2_1:4,P00552,1.06758,NO,10,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.921,-3.683,1.762,,,,,,,1.862,,71.59,HOP,-2.10733,0.168804,0.00289233,1.06758 kka2_1:8_H106V,kka2_1:8_106,Kka2,kka2_1:8,P00552,1.06765,NO,106,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-3.13,-3.002,-0.128,,1.065,,a,0.87,-0.95,15.956,15.956,71.59,PBH,-2.10433,0.100394,0.00730778,1.06765 kka2_1:8_H106V,kka2_1:8_106,Kka2,kka2_1:8,P00552,1.06765,NO,106,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-3.13,-3.002,-0.128,,1.065,,a,0.87,-0.95,15.956,15.956,71.59,PBH,-2.10433,0.100394,0.00730778,1.06765 PSD95pdz3_R313T,PSD95pdz3_313,PSD95pdz3,PSD95pdz3,P31016,1.06768,NO,313,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.582,-3.103,1.521,6.63563,,,,,18.3955,,,,BBH,-1.59733,0.0758425,0.000840067,1.06768 beta-lactamase_0_R118V,beta-lactamase_0_118,TEM-1,beta-lactamase_0,P62593,1.06769,NO,118,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.413,-3.595,1.182,,0.457,H,A,1.2,1.39,3.961,,77.62,HBA,-1.785,0.0500837,0.00538794,1.06769 gb1_D273V,gb1_273,gb1,gb1,P06654,1.06769,NO,273,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.998,-3.45,1.452,,,,,,,3.514,3.514,37.28,AAH,-1.72767,0.177985,0.00318903,1.06769 gb1_E245P,gb1_245,gb1,gb1,P06654,1.06769,NO,245,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.725,-3.39,0.665,,,,,,,0.712,,45.54,PAH,-1.84567,0.177985,0.00158611,1.06769 beta-lactamase_0_A215S,beta-lactamase_0_215,TEM-1,beta-lactamase_0,P62593,1.06779,NO,215,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.503,-2.232,0.729,,,,a,0.46,-0.93,0.494,,74.48,HHO,-1.42633,0.0500837,0.00544007,1.06779 kka2_1:8_D52S,kka2_1:8_52,Kka2,kka2_1:8,P00552,1.06786,NO,52,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.271,-3.212,0.941,,0.22,E,B,0.75,0.8,5.447,,71.59,PAH,-2.38367,0.100394,0.00175694,1.06786 kka2_1:8_D52S,kka2_1:8_52,Kka2,kka2_1:8,P00552,1.06786,NO,52,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.271,-3.212,0.941,,0.22,E,B,0.75,0.8,5.447,,71.59,PAH,-2.38367,0.100394,0.00175694,1.06786 kka2_1:2_V80R,kka2_1:2_80,Kka2,kka2_1:2,P00552,1.06787,NO,80,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.144,-4.199,3.055,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.295029,0.00488211,1.06787 kka2_1:1_S251H,kka2_1:1_251,Kka2,kka2_1:1,P00552,1.06788,NO,251,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.636,-3.222,0.586,,0.712,H,A,0.27,-0.25,1.356,,71.59,APP,-2.09367,0.520039,0.0138916,1.06788 kka2_1:4_Q252L,kka2_1:4_252,Kka2,kka2_1:4,P00552,1.06796,NO,252,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.63,-3.66,1.03,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.168804,0.0121001,1.06796 PSD95pdz3_G356M,PSD95pdz3_356,PSD95pdz3,PSD95pdz3,P31016,1.06796,NO,356,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.008,-4.612,3.604,4.8656,,,,,11.9575,,,,BOA,-1.22933,0.0758425,0.000623061,1.06796 kka2_1:2_A248G,kka2_1:2_248,Kka2,kka2_1:2,P00552,1.06798,NO,248,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.124,-2.636,0.512,,0.825,S,b,0.46,0.46,,,92.05,HHO,-2.15,0.295029,0.0125484,1.06798 PSD95pdz3_T321P,PSD95pdz3_321,PSD95pdz3,PSD95pdz3,P31016,1.06799,NO,321,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.391,-3.336,1.945,5.19953,,,,,20.3371,,,,PPO,-1.306,0.0758425,0.00106992,1.06799 kka2_1:8_R202D,kka2_1:8_202,Kka2,kka2_1:8,P00552,1.06805,NO,202,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.761,-2.83,1.069,,0.607,E,B,1.2,0.48,1.409,,52.27,OBH,-1.41067,0.100394,0.00696498,1.06805 kka2_1:8_R202D,kka2_1:8_202,Kka2,kka2_1:8,P00552,1.06805,NO,202,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.761,-2.83,1.069,,0.607,E,B,1.2,0.48,1.409,,52.27,OBH,-1.41067,0.100394,0.00696498,1.06805 beta-lactamase_0_T178F,beta-lactamase_0_178,TEM-1,beta-lactamase_0,P62593,1.06807,NO,178,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-0.791,-4.067,3.276,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.0500837,0.000684366,1.06807 kka2_1:4_G43M,kka2_1:4_43,Kka2,kka2_1:4,P00552,1.06814,NO,43,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.587,-4.94,3.353,,0.862,T,l,0.75,-0.67,2.247,,63.26,POB,-2.18533,0.168804,0.0071925,1.06814 beta-lactamase_0_G194I,beta-lactamase_0_194,TEM-1,beta-lactamase_0,P62593,1.06815,NO,194,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.396,-4.133,2.737,,0.276,S,b,0.29,0.36,3.017,,67.83,POA,-1.832,0.0500837,0.00392163,1.06815 kka2_1:2_T73S,kka2_1:2_73,Kka2,kka2_1:2,P00552,1.06816,NO,73,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.51,-2.503,-0.007,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.295029,0.00628605,1.06816 kka2_1:8_A166V,kka2_1:8_166,Kka2,kka2_1:8,P00552,1.06819,NO,166,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.407,-3.015,0.608,,0.534,,B,1.04,1.03,13.995,13.995,71.59,HHO,-2.421,0.100394,0.00799912,1.06819 kka2_1:8_A166V,kka2_1:8_166,Kka2,kka2_1:8,P00552,1.06819,NO,166,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.407,-3.015,0.608,,0.534,,B,1.04,1.03,13.995,13.995,71.59,HHO,-2.421,0.100394,0.00799912,1.06819 gb1_E245Y,gb1_245,gb1,gb1,P06654,1.06822,NO,245,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.725,-3.898,1.173,,,,,,,0.712,,45.54,PAH,-1.84567,0.177985,0.00158611,1.06822 kka2_1:8_A129G,kka2_1:8_129,Kka2,kka2_1:8,P00552,1.06824,NO,129,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.656,-2.673,1.017,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.100394,0.00726862,1.06824 kka2_1:8_A129G,kka2_1:8_129,Kka2,kka2_1:8,P00552,1.06824,NO,129,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.656,-2.673,1.017,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.100394,0.00726862,1.06824 PSD95pdz3_H317S,PSD95pdz3_317,PSD95pdz3,PSD95pdz3,P31016,1.06827,NO,317,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-1.627,-3.067,1.44,6.19713,,,,,25.885,,,,HBB,-1.613,0.0758425,0.00111619,1.06827 kka2_1:8_R122T,kka2_1:8_122,Kka2,kka2_1:8,P00552,1.06829,NO,122,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.175,-2.452,0.277,,0.487,H,A,1.2,0.26,22.675,22.675,71.59,BBH,-1.53833,0.100394,0.00736512,1.06829 kka2_1:8_R122T,kka2_1:8_122,Kka2,kka2_1:8,P00552,1.06829,NO,122,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.175,-2.452,0.277,,0.487,H,A,1.2,0.26,22.675,22.675,71.59,BBH,-1.53833,0.100394,0.00736512,1.06829 PSD95pdz3_I316S,PSD95pdz3_316,PSD95pdz3,PSD95pdz3,P31016,1.06832,NO,316,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.63,-3.292,1.662,5.46166,,,,,19.005,,,,HHB,-1.62733,0.0758425,0.00112762,1.06832 PSD95pdz3_R313A,PSD95pdz3_313,PSD95pdz3,PSD95pdz3,P31016,1.06832,NO,313,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.582,-2.759,1.177,6.63563,,,,,18.3955,,,,BBH,-1.59733,0.0758425,0.000840067,1.06832 kka2_1:8_S32T,kka2_1:8_32,Kka2,kka2_1:8,P00552,1.06833,NO,32,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-0.804,-3,2.196,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.100394,0.00149998,1.06833 kka2_1:8_S32T,kka2_1:8_32,Kka2,kka2_1:8,P00552,1.06833,NO,32,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-0.804,-3,2.196,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.100394,0.00149998,1.06833 PSD95pdz3_N363Q,PSD95pdz3_363,PSD95pdz3,PSD95pdz3,P31016,1.06837,NO,363,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-1.41,-3.356,1.946,5.23349,,,,,20.7037,,,,HPO,-1.29433,0.0758425,0.000524014,1.06837 beta-lactamase_0_T112I,beta-lactamase_0_112,TEM-1,beta-lactamase_0,P62593,1.06847,NO,112,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.186,-3.949,1.763,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.0500837,0.00531334,1.06847 kka2_1:2_G21H,kka2_1:2_21,Kka2,kka2_1:2,P00552,1.06847,NO,21,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.368,-2.564,1.196,,0.586,T,l,0.29,-0.75,2.026,,71.59,HOH,-2.10167,0.295029,0.00709648,1.06847 kka2_1:8_G164D,kka2_1:8_164,Kka2,kka2_1:8,P00552,1.06851,NO,164,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.869,-2.664,1.795,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.100394,0.00442091,1.06851 kka2_1:8_G164D,kka2_1:8_164,Kka2,kka2_1:8,P00552,1.06851,NO,164,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.869,-2.664,1.795,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.100394,0.00442091,1.06851 gb1_E241S,gb1_241,gb1,gb1,P06654,1.06854,NO,241,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.672,-2.853,1.181,,,,,,,0.344,,11.83,OAP,-1.27933,0.177985,0.00250604,1.06854 gb1_E268C,gb1_268,gb1,gb1,P06654,1.06854,NO,268,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.918,-4.968,3.05,,,,,,,0.637,,37.28,OAH,-1.59733,0.177985,0.00423953,1.06854 beta-lactamase_0_T269N,beta-lactamase_0_269,TEM-1,beta-lactamase_0,P62593,1.06868,NO,269,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.0500837,0.00950944,1.06868 kka2_1:2_A65E,kka2_1:2_65,Kka2,kka2_1:2,P00552,1.0687,NO,65,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.744,-2.135,0.391,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.295029,0.00709258,1.0687 gb1_T277E,gb1_277,gb1,gb1,P06654,1.06875,NO,277,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.771,-3.229,1.458,,,,,,,0.824,,35.71,BPH,-1.54833,0.177985,0.00348258,1.06875 kka2_1:8_L243M,kka2_1:8_243,Kka2,kka2_1:8,P00552,1.0688,NO,243,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-2.651,-4.688,2.037,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.100394,0.00884927,1.0688 kka2_1:8_L243M,kka2_1:8_243,Kka2,kka2_1:8,P00552,1.0688,NO,243,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-2.651,-4.688,2.037,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.100394,0.00884927,1.0688 PSD95pdz3_T385I,PSD95pdz3_385,PSD95pdz3,PSD95pdz3,P31016,1.06882,NO,385,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.533,-3.421,1.888,5.57157,,,,,23.6871,4.527,,87.71,PPH,-1.56567,0.0758425,0.000545119,1.06882 beta-lactamase_0_M67L,beta-lactamase_0_67,TEM-1,beta-lactamase_0,P62593,1.06884,NO,67,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-2.231,-2.657,0.426,,0.006,G,P,0.55,-0.81,24.165,24.165,65.03,HHP,-1.502,0.0500837,0.00409753,1.06884 kka2_1:4_A229Y,kka2_1:4_229,Kka2,kka2_1:4,P00552,1.06886,NO,229,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.739,-4.342,2.603,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.168804,0.00942138,1.06886 beta-lactamase_39_I171A,beta-lactamase_39_171,TEM-1,beta-lactamase_39,P62593,1.06888,NO,171,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-2.431,-2.242,-0.189,,0.361,,B,0.48,0.53,16.954,16.954,77.62,HHO,-1.55533,0.0495842,0.00623355,1.06888 kka2_1:8_M116A,kka2_1:8_116,Kka2,kka2_1:8,P00552,1.06891,NO,116,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-2.482,-2.16,-0.322,,,H,A,1.59,-0.88,4.659,,71.59,HHH,-1.63867,0.100394,0.00745147,1.06891 kka2_1:8_M116A,kka2_1:8_116,Kka2,kka2_1:8,P00552,1.06891,NO,116,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-2.482,-2.16,-0.322,,,H,A,1.59,-0.88,4.659,,71.59,HHH,-1.63867,0.100394,0.00745147,1.06891 beta-lactamase_0_N173R,beta-lactamase_0_173,TEM-1,beta-lactamase_0,P62593,1.06892,NO,173,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-2.663,-3.837,1.174,,1.044,T,l,0.61,1.25,1.133,,77.62,OPA,-1.46633,0.0500837,0.0033769,1.06892 beta-lactamase_2500_E210K,beta-lactamase_2500_210,TEM-1,beta-lactamase_2500,P62593,1.06893,NO,210,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.319,-2.868,0.549,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.361275,0.00663582,1.06893 gb1_E268A,gb1_268,gb1,gb1,P06654,1.06896,NO,268,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.918,-3.033,1.115,,,,,,,0.637,,37.28,OAH,-1.59733,0.177985,0.00423953,1.06896 kka2_1:8_L165D,kka2_1:8_165,Kka2,kka2_1:8,P00552,1.069,NO,165,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-2.453,-3.848,1.395,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.100394,0.00801161,1.069 kka2_1:8_L165D,kka2_1:8_165,Kka2,kka2_1:8,P00552,1.069,NO,165,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-2.453,-3.848,1.395,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.100394,0.00801161,1.069 kka2_1:2_G74D,kka2_1:2_74,Kka2,kka2_1:2,P00552,1.06902,NO,74,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.18,-1.88,0.7,,0.621,T,l,0.75,0.2,1.446,,64.39,POH,-1.91667,0.295029,0.00587035,1.06902 PSD95pdz3_I389S,PSD95pdz3_389,PSD95pdz3,PSD95pdz3,P31016,1.06902,NO,389,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.628,-3.388,1.76,5.15116,,,,,14.8038,1.498,,87.71,HHH,-1.52167,0.0758425,0.00148097,1.06902 kka2_1:8_P167D,kka2_1:8_167,Kka2,kka2_1:8,P00552,1.06904,NO,167,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-2.403,-3.015,0.612,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.100394,0.00543203,1.06904 kka2_1:8_P167D,kka2_1:8_167,Kka2,kka2_1:8,P00552,1.06904,NO,167,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-2.403,-3.015,0.612,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.100394,0.00543203,1.06904 beta-lactamase_0_I285W,beta-lactamase_0_285,TEM-1,beta-lactamase_0,P62593,1.06907,NO,285,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.0500837,0.101555,1.06907 kka2_1:4_A65E,kka2_1:4_65,Kka2,kka2_1:4,P00552,1.06911,NO,65,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.744,-2.135,0.391,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.168804,0.00709258,1.06911 kka2_1:4_Q61R,kka2_1:4_61,Kka2,kka2_1:4,P00552,1.06913,NO,61,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.982,-2.952,-0.03,,0.591,H,A,0.64,0.41,3.484,,65.53,HPA,-1.85667,0.168804,0.00612092,1.06913 PSD95pdz3_F325M,PSD95pdz3_325,PSD95pdz3,PSD95pdz3,P31016,1.06915,NO,325,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.524,-3.937,2.413,5.50654,,,,,12.7236,,,,OHP,-1.314,0.0758425,0.00102273,1.06915 beta-lactamase_39_I171H,beta-lactamase_39_171,TEM-1,beta-lactamase_39,P62593,1.06916,NO,171,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-2.431,-4.817,2.386,,0.361,,B,0.48,0.53,16.954,16.954,77.62,HHO,-1.55533,0.0495842,0.00623355,1.06916 PSD95pdz3_V365L,PSD95pdz3_365,PSD95pdz3,PSD95pdz3,P31016,1.06918,NO,365,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.592,-2.617,1.025,5.03791,,,,,18.9657,2.364,,81.35,OHA,-1.288,0.0758425,0.000649764,1.06918 beta-lactamase_0_L55H,beta-lactamase_0_55,TEM-1,beta-lactamase_0,P62593,1.06919,NO,55,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.86,-4.855,2.995,,0.372,E,A,0.55,-0.36,1.967,,63.99,HHA,-2.247,0.0500837,0.00403741,1.06919 kka2_1:8_T72L,kka2_1:8_72,Kka2,kka2_1:8,P00552,1.06919,NO,72,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.38,-3.619,1.239,,0.784,H,A,0.22,0.29,3.603,,65.53,HPP,-2.238,0.100394,0.00750756,1.06919 kka2_1:8_T72L,kka2_1:8_72,Kka2,kka2_1:8,P00552,1.06919,NO,72,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.38,-3.619,1.239,,0.784,H,A,0.22,0.29,3.603,,65.53,HPP,-2.238,0.100394,0.00750756,1.06919 beta-lactamase_0_V101T,beta-lactamase_0_101,TEM-1,beta-lactamase_0,P62593,1.06923,NO,101,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.295,-3.446,2.151,,0.342,,B,0.44,0,1.61,,73.08,HHA,-1.54367,0.0500837,0.00374492,1.06923 kka2_1:8_L259A,kka2_1:8_259,Kka2,kka2_1:8,P00552,1.06923,NO,259,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.088,-2.512,1.424,,0.036,H,A,1.59,-0.15,1.83,,48.48,BHH,-1.15167,0.100394,0.0206964,1.06923 kka2_1:8_L259A,kka2_1:8_259,Kka2,kka2_1:8,P00552,1.06923,NO,259,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.088,-2.512,1.424,,0.036,H,A,1.59,-0.15,1.83,,48.48,BHH,-1.15167,0.100394,0.0206964,1.06923 PSD95pdz3_Q391M,PSD95pdz3_391,PSD95pdz3,PSD95pdz3,P31016,1.06923,NO,391,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-1.699,-3.937,2.238,5.50275,,,,,12.6589,,,,HPH,-1.481,0.0758425,0.000990786,1.06923 kka2_1:8_S11I,kka2_1:8_11,Kka2,kka2_1:8,P00552,1.06924,NO,11,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.322,-2.514,0.192,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.100394,0.00381691,1.06924 kka2_1:8_S11I,kka2_1:8_11,Kka2,kka2_1:8,P00552,1.06924,NO,11,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.322,-2.514,0.192,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.100394,0.00381691,1.06924 kka2_1:8_D127E,kka2_1:8_127,Kka2,kka2_1:8,P00552,1.06927,NO,127,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.364,-2.659,1.295,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.100394,0.00660501,1.06927 kka2_1:8_D127E,kka2_1:8_127,Kka2,kka2_1:8,P00552,1.06927,NO,127,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.364,-2.659,1.295,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.100394,0.00660501,1.06927 kka2_1:4_I141Q,kka2_1:4_141,Kka2,kka2_1:4,P00552,1.06929,NO,141,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.495,-4.325,2.83,,0.068,H,A,0.48,-0.01,2.144,,92.05,BHA,-1.689,0.168804,0.00744745,1.06929 kka2_1:8_E235K,kka2_1:8_235,Kka2,kka2_1:8,P00552,1.06929,NO,235,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.955,-2.949,0.994,,0.631,H,A,1.52,0.12,,,65.53,OAH,-2.07267,0.100394,0.0102806,1.06929 kka2_1:8_E235K,kka2_1:8_235,Kka2,kka2_1:8,P00552,1.06929,NO,235,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.955,-2.949,0.994,,0.631,H,A,1.52,0.12,,,65.53,OAH,-2.07267,0.100394,0.0102806,1.06929 beta-lactamase_0_D113P,beta-lactamase_0_113,TEM-1,beta-lactamase_0,P62593,1.0693,NO,113,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.829,-3.062,1.233,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.0500837,0.00474112,1.0693 kka2_1:8_D183H,kka2_1:8_183,Kka2,kka2_1:8,P00552,1.06932,NO,183,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.204,-4.489,3.285,,0.518,.,b,0.75,0.25,0.347,,52.27,AAH,-1.40533,0.100394,0.00426304,1.06932 kka2_1:8_D183H,kka2_1:8_183,Kka2,kka2_1:8,P00552,1.06932,NO,183,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.204,-4.489,3.285,,0.518,.,b,0.75,0.25,0.347,,52.27,AAH,-1.40533,0.100394,0.00426304,1.06932 beta-lactamase_156_E26G,beta-lactamase_156_26,TEM-1,beta-lactamase_156,P62593,1.06946,NO,26,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.454,-2.639,0.185,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.111618,0.00297948,1.06946 PSD95pdz3_N326T,PSD95pdz3_326,PSD95pdz3,PSD95pdz3,P31016,1.06955,NO,326,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-1.41,-2.878,1.468,5.52537,,,,,19.0688,,,,HPH,-1.52133,0.0758425,0.00101078,1.06955 beta-lactamase_39_W208H,beta-lactamase_39_208,TEM-1,beta-lactamase_39,P62593,1.0696,NO,208,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-0.818,-4.68,3.862,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.0495842,0.00126609,1.0696 beta-lactamase_0_E164W,beta-lactamase_0_164,TEM-1,beta-lactamase_0,P62593,1.06961,NO,164,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-0.948,-5.346,4.398,,0.011,T,B,1.04,-0.4,1.011,,64.69,HAO,-1.388,0.0500837,0.00137286,1.06961 kka2_1:2_Q26H,kka2_1:2_26,Kka2,kka2_1:2,P00552,1.06965,NO,26,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.18,-3.435,1.255,,0.448,E,B,0.4,0.44,5.022,,92.05,HPP,-2.11167,0.295029,0.00708962,1.06965 kka2_1:8_E161R,kka2_1:8_161,Kka2,kka2_1:8,P00552,1.06966,NO,161,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.581,-3.888,2.307,,0.829,G,A,1.04,2.24,11.923,11.923,92.05,AAB,-1.861,0.100394,0.00760103,1.06966 kka2_1:8_E161R,kka2_1:8_161,Kka2,kka2_1:8,P00552,1.06966,NO,161,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.581,-3.888,2.307,,0.829,G,A,1.04,2.24,11.923,11.923,92.05,AAB,-1.861,0.100394,0.00760103,1.06966 beta-lactamase_39_V214G,beta-lactamase_39_214,TEM-1,beta-lactamase_39,P62593,1.06968,NO,214,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.299,-3.571,2.272,,0.375,S,A,0.44,-0.44,18.838,18.838,74.48,BHH,-1.53733,0.0495842,0.00628442,1.06968 kka2_1:8_E3W,kka2_1:8_3,Kka2,kka2_1:8,P00552,1.06969,NO,3,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.199,-4.936,2.737,,,,,,,7.22,,92.05,HAP,-2.11567,0.100394,0.00267607,1.06969 kka2_1:8_E3W,kka2_1:8_3,Kka2,kka2_1:8,P00552,1.06969,NO,3,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.199,-4.936,2.737,,,,,,,7.22,,92.05,HAP,-2.11567,0.100394,0.00267607,1.06969 beta-lactamase_0_N173S,beta-lactamase_0_173,TEM-1,beta-lactamase_0,P62593,1.06973,NO,173,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-2.663,-3.203,0.54,,1.044,T,l,0.61,1.25,1.133,,77.62,OPA,-1.46633,0.0500837,0.0033769,1.06973 beta-lactamase_156_T138K,beta-lactamase_156_138,TEM-1,beta-lactamase_156,P62593,1.06975,NO,138,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.506,-2.186,-0.32,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.111618,0.00487868,1.06975 beta-lactamase_0_L49V,beta-lactamase_0_49,TEM-1,beta-lactamase_0,P62593,1.06977,NO,49,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.897,-2.549,0.652,,0.131,T,A,0.55,0.04,13.838,13.838,64.69,AHP,-1.99233,0.0500837,0.00401477,1.06977 kka2_1:8_F20V,kka2_1:8_20,Kka2,kka2_1:8,P00552,1.06979,NO,20,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-3.354,-2.808,-0.546,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.100394,0.00701744,1.06979 kka2_1:8_F20V,kka2_1:8_20,Kka2,kka2_1:8,P00552,1.06979,NO,20,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-3.354,-2.808,-0.546,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.100394,0.00701744,1.06979 beta-lactamase_0_L205A,beta-lactamase_0_205,TEM-1,beta-lactamase_0,P62593,1.06981,NO,205,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.922,-3.132,2.21,,,H,A,0.55,-0.46,1.065,,42.31,PHH,-1.57767,0.0500837,0.00255802,1.06981 kka2_1:8_Q61K,kka2_1:8_61,Kka2,kka2_1:8,P00552,1.06984,NO,61,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.982,-3.601,0.619,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.100394,0.00612092,1.06984 kka2_1:8_Q61K,kka2_1:8_61,Kka2,kka2_1:8,P00552,1.06984,NO,61,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.982,-3.601,0.619,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.100394,0.00612092,1.06984 E1_Ubiquitin_T68N,E1_Ubiquitin_68,Uba1,E1_Ubiquitin,P0CG63,1.06985,NO,68,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,,,,,,,,,,,,,OPH,-1.039,0.18783,0.00314321,1.06985 beta-lactamase_39_V214M,beta-lactamase_39_214,TEM-1,beta-lactamase_39,P62593,1.06987,NO,214,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.299,-4.251,2.952,,0.375,S,A,0.44,-0.44,18.838,18.838,74.48,BHH,-1.53733,0.0495842,0.00628442,1.06987 kka2_1:8_G164R,kka2_1:8_164,Kka2,kka2_1:8,P00552,1.06989,NO,164,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.869,-3.953,3.084,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.100394,0.00442091,1.06989 kka2_1:8_G164R,kka2_1:8_164,Kka2,kka2_1:8,P00552,1.06989,NO,164,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-0.869,-3.953,3.084,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.100394,0.00442091,1.06989 kka2_1:4_Q252K,kka2_1:4_252,Kka2,kka2_1:4,P00552,1.06991,NO,252,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.63,-2.767,0.137,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.168804,0.0121001,1.06991 kka2_1:8_A110H,kka2_1:8_110,Kka2,kka2_1:8,P00552,1.06993,NO,110,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.064,-3.65,1.586,,0.175,H,A,1.04,-1.19,11.413,11.413,71.59,OHA,-1.91867,0.100394,0.00759851,1.06993 kka2_1:8_A110H,kka2_1:8_110,Kka2,kka2_1:8,P00552,1.06993,NO,110,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.064,-3.65,1.586,,0.175,H,A,1.04,-1.19,11.413,11.413,71.59,OHA,-1.91867,0.100394,0.00759851,1.06993 beta-lactamase_0_G243P,beta-lactamase_0_243,TEM-1,beta-lactamase_0,P62593,1.06996,NO,243,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.0500837,0.00464034,1.06996 PSD95pdz3_E334R,PSD95pdz3_334,PSD95pdz3,PSD95pdz3,P31016,1.06998,NO,334,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.404,-3.165,1.761,5.60175,,,,,53.09,,,,OAO,-1.14,0.0758425,0.000912998,1.06998 kka2_1:4_C31R,kka2_1:4_31,Kka2,kka2_1:4,P00552,1.06999,NO,31,C,R,CR,Special,PositiveCharge,5.07,6.34148,1.27148,180,121,174,53,108.5,173.4,64.9,-2.246,-1.901,-0.345,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.168804,0.00681582,1.06999 beta-lactamase_39_S201M,beta-lactamase_39_201,TEM-1,beta-lactamase_39,P62593,1.07,NO,201,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.183,-4.493,3.31,,0.064,H,A,0.27,-0.07,3.54,,64.69,HPB,-1.451,0.0495842,0.00198815,1.07 gb1_D248V,gb1_248,gb1,gb1,P06654,1.07,NO,248,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.569,-3.446,1.877,,,,,,,0.344,,11.83,HAH,-1.673,0.177985,0.001865,1.07 gb1_E245L,gb1_245,gb1,gb1,P06654,1.07,NO,245,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.725,-3.094,0.369,,,,,,,0.712,,45.54,PAH,-1.84567,0.177985,0.00158611,1.07 gb1_E268N,gb1_268,gb1,gb1,P06654,1.07,NO,268,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.918,-2.294,0.376,,,,,,,0.637,,37.28,OAH,-1.59733,0.177985,0.00423953,1.07 PSD95pdz3_G335N,PSD95pdz3_335,PSD95pdz3,PSD95pdz3,P31016,1.07003,NO,335,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.008,-3.13,2.122,4.76223,,,,,22.4225,,,,AOH,-1.34733,0.0758425,0.000900493,1.07003 kka2_1:4_T72Y,kka2_1:4_72,Kka2,kka2_1:4,P00552,1.07004,NO,72,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.38,-4.457,2.077,,0.784,H,A,0.82,0.29,6.463,,65.53,HPP,-2.238,0.168804,0.00750756,1.07004 kka2_1:4_D154C,kka2_1:4_154,Kka2,kka2_1:4,P00552,1.07009,NO,154,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.876,-5.188,4.312,,0.457,,b,0.29,1.48,15.641,15.641,52.65,HAP,-1.52467,0.168804,0.00292633,1.07009 gb1_D266I,gb1_266,gb1,gb1,P06654,1.0701,NO,266,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.261,-3.7,2.439,,,,,,,0.638,,45.54,HAO,-1.59333,0.177985,0.00394694,1.0701 kka2_1:4_V242L,kka2_1:4_242,Kka2,kka2_1:4,P00552,1.07014,NO,242,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-2.687,-3.55,0.863,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.168804,0.0102575,1.07014 kka2_1:8_L165K,kka2_1:8_165,Kka2,kka2_1:8,P00552,1.07016,NO,165,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-2.453,-2.336,-0.117,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.100394,0.00801161,1.07016 kka2_1:8_L165K,kka2_1:8_165,Kka2,kka2_1:8,P00552,1.07016,NO,165,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-2.453,-2.336,-0.117,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.100394,0.00801161,1.07016 kka2_1:8_A65F,kka2_1:8_65,Kka2,kka2_1:8,P00552,1.0702,NO,65,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.744,-4.347,2.603,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.100394,0.00709258,1.0702 kka2_1:8_A65F,kka2_1:8_65,Kka2,kka2_1:8,P00552,1.0702,NO,65,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.744,-4.347,2.603,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.100394,0.00709258,1.0702 kka2_1:4_Q136A,kka2_1:4_136,Kka2,kka2_1:4,P00552,1.07021,NO,136,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-3.021,-3.149,0.128,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.168804,0.00624149,1.07021 beta-lactamase_0_G243A,beta-lactamase_0_243,TEM-1,beta-lactamase_0,P62593,1.07022,NO,243,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.0500837,0.00464034,1.07022 beta-lactamase_39_E210G,beta-lactamase_39_210,TEM-1,beta-lactamase_39,P62593,1.07023,NO,210,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.319,-3.66,1.341,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.0495842,0.00663582,1.07023 kka2_1:4_F37L,kka2_1:4_37,Kka2,kka2_1:4,P00552,1.07027,NO,37,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.427,-2.514,1.087,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.168804,0.00586193,1.07027 kka2_1:2_D134K,kka2_1:2_134,Kka2,kka2_1:2,P00552,1.0703,NO,134,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.969,-3.503,2.534,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.295029,0.00270812,1.0703 kka2_1:8_G181H,kka2_1:8_181,Kka2,kka2_1:8,P00552,1.0703,NO,181,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-2.698,-2.933,0.235,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.100394,0.00728319,1.0703 kka2_1:8_G181H,kka2_1:8_181,Kka2,kka2_1:8,P00552,1.0703,NO,181,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-2.698,-2.933,0.235,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.100394,0.00728319,1.0703 gb1_Q228R,gb1_228,gb1,gb1,P06654,1.07031,NO,228,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,,,,,,,,,,,,,OPH,-1.282,0.177985,0.00391043,1.07031 beta-lactamase_39_W208T,beta-lactamase_39_208,TEM-1,beta-lactamase_39,P62593,1.07036,NO,208,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-0.818,-3.646,2.828,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.0495842,0.00126609,1.07036 kka2_1:8_V97I,kka2_1:8_97,Kka2,kka2_1:8,P00552,1.07037,NO,97,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.453,-2.403,0.95,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.100394,0.00737869,1.07037 kka2_1:8_V97I,kka2_1:8_97,Kka2,kka2_1:8,P00552,1.07037,NO,97,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.453,-2.403,0.95,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.100394,0.00737869,1.07037 kka2_1:8_L241V,kka2_1:8_241,Kka2,kka2_1:8,P00552,1.07041,NO,241,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.158,-3.12,1.962,,0.08,H,A,1.59,-0.82,1.136,,63.26,HHH,-1.58533,0.100394,0.0117299,1.07041 kka2_1:8_L241V,kka2_1:8_241,Kka2,kka2_1:8,P00552,1.07041,NO,241,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.158,-3.12,1.962,,0.08,H,A,1.59,-0.82,1.136,,63.26,HHH,-1.58533,0.100394,0.0117299,1.07041 gb1_V247R,gb1_247,gb1,gb1,P06654,1.07042,NO,247,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.711,-3.83,2.119,,,,,,,0.805,,44.87,HHA,-1.485,0.177985,0.00435373,1.07042 beta-lactamase_0_E195H,beta-lactamase_0_195,TEM-1,beta-lactamase_0,P62593,1.07045,NO,195,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.186,-3.381,1.195,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.0500837,0.00496565,1.07045 kka2_1:8_Q26N,kka2_1:8_26,Kka2,kka2_1:8,P00552,1.07045,NO,26,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.18,-3.808,1.628,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.100394,0.00708962,1.07045 kka2_1:8_Q26N,kka2_1:8_26,Kka2,kka2_1:8,P00552,1.07045,NO,26,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.18,-3.808,1.628,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.100394,0.00708962,1.07045 PSD95pdz3_G333N,PSD95pdz3_333,PSD95pdz3,PSD95pdz3,P31016,1.07048,NO,333,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.008,-3.13,2.122,5.09445,,,,,48.755,,,,AOA,-1.22533,0.0758425,0.00092544,1.07048 beta-lactamase_39_E87A,beta-lactamase_39_87,TEM-1,beta-lactamase_39,P62593,1.07051,NO,87,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.421,-3.209,1.788,,0.048,,B,1.04,0.92,15.231,15.231,64.69,PAP,-1.969,0.0495842,0.00337888,1.07051 kka2_1:2_E230D,kka2_1:2_230,Kka2,kka2_1:2,P00552,1.07058,NO,230,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.672,-2.56,-0.112,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.295029,0.00920051,1.07058 kka2_1:8_L53P,kka2_1:8_53,Kka2,kka2_1:8,P00552,1.07059,NO,53,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-2.681,-2.005,-0.676,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.100394,0.00671168,1.07059 kka2_1:8_L53P,kka2_1:8_53,Kka2,kka2_1:8,P00552,1.07059,NO,53,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-2.681,-2.005,-0.676,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.100394,0.00671168,1.07059 kka2_1:8_P45E,kka2_1:8_45,Kka2,kka2_1:8,P00552,1.07059,NO,45,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.774,-2.616,0.842,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.100394,0.00590481,1.07059 kka2_1:8_P45E,kka2_1:8_45,Kka2,kka2_1:8,P00552,1.07059,NO,45,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.774,-2.616,0.842,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.100394,0.00590481,1.07059 kka2_1:4_A110V,kka2_1:4_110,Kka2,kka2_1:4,P00552,1.07064,NO,110,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.064,-2.939,0.875,,0.175,H,A,0.46,-1.19,23.237,23.237,71.59,OHA,-1.91867,0.168804,0.00759851,1.07064 beta-lactamase_0_A124I,beta-lactamase_0_124,TEM-1,beta-lactamase_0,P62593,1.07066,NO,124,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.181,-3.529,2.348,,,H,A,0.46,-0.9,1.876,,64.34,HHH,-1.152,0.0500837,0.00481399,1.07066 beta-lactamase_0_V78D,beta-lactamase_0_78,TEM-1,beta-lactamase_0,P62593,1.07071,NO,78,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.459,-4.082,2.623,,,H,A,0.44,-0.47,16.615,16.615,63.64,HHH,-1.17833,0.0500837,0.00492501,1.07071 beta-lactamase_0_N152S,beta-lactamase_0_152,TEM-1,beta-lactamase_0,P62593,1.07081,NO,152,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-2.757,-1.988,-0.769,,0.863,H,A,0.61,0.92,2.151,,77.62,BPH,-2.97,0.0500837,0.00471429,1.07081 PSD95pdz3_A343Y,PSD95pdz3_343,PSD95pdz3,PSD95pdz3,P31016,1.07087,NO,343,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.307,-3.844,2.537,5.585,,,,,14.728,,,,HHO,-1.22067,0.0758425,0.000798084,1.07087 kka2_1:4_A168S,kka2_1:4_168,Kka2,kka2_1:4,P00552,1.07088,NO,168,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.989,-2.65,0.661,,0.67,H,A,0.46,0.15,,,64.39,OHA,-2.12933,0.168804,0.00806773,1.07088 beta-lactamase_0_I280L,beta-lactamase_0_280,TEM-1,beta-lactamase_0,P62593,1.07089,NO,280,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.0500837,0.0530888,1.07089 PSD95pdz3_S320R,PSD95pdz3_320,PSD95pdz3,PSD95pdz3,P31016,1.0709,NO,320,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.519,-3.39,1.871,5.81757,,,,,21.4517,,,,OPP,-1.306,0.0758425,0.00108158,1.0709 beta-lactamase_156_H110Y,beta-lactamase_156_110,TEM-1,beta-lactamase_156,P62593,1.07097,NO,110,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-1.706,-2.513,0.807,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.111618,0.00441499,1.07097 PSD95pdz3_G333E,PSD95pdz3_333,PSD95pdz3,PSD95pdz3,P31016,1.07097,NO,333,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.008,-3.347,2.339,5.09445,,,,,48.755,,,,AOA,-1.22533,0.0758425,0.00092544,1.07097 PSD95pdz3_I389Q,PSD95pdz3_389,PSD95pdz3,PSD95pdz3,P31016,1.07097,NO,389,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.628,-4.03,2.402,5.15116,,,,,14.8038,1.498,,87.71,HHH,-1.52167,0.0758425,0.00148097,1.07097 kka2_1:4_R202N,kka2_1:4_202,Kka2,kka2_1:4,P00552,1.07103,NO,202,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.761,-3.087,1.326,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.168804,0.00696498,1.07103 beta-lactamase_39_M209I,beta-lactamase_39_209,TEM-1,beta-lactamase_39,P62593,1.07108,NO,209,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.442,-3.121,1.679,,,H,A,0.55,-0.97,1.167,,64.69,HHA,-1.52633,0.0495842,0.00625021,1.07108 beta-lactamase_0_L199E,beta-lactamase_0_199,TEM-1,beta-lactamase_0,P62593,1.07111,NO,199,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-2.942,-2.604,-0.338,,0.832,H,A,0.55,0.42,10.85,10.85,77.62,PHH,-2.32933,0.0500837,0.0048649,1.07111 kka2_1:2_A110W,kka2_1:2_110,Kka2,kka2_1:2,P00552,1.07111,NO,110,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.064,-5.542,3.478,,0.175,H,A,0.46,-1.19,23.237,23.237,71.59,OHA,-1.91867,0.295029,0.00759851,1.07111 kka2_1:8_A137H,kka2_1:8_137,Kka2,kka2_1:8,P00552,1.07112,NO,137,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.156,-4.943,2.787,,0.029,H,A,1.04,0.34,2.886,,63.26,PHB,-2.559,0.100394,0.00515054,1.07112 kka2_1:8_A137H,kka2_1:8_137,Kka2,kka2_1:8,P00552,1.07112,NO,137,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.156,-4.943,2.787,,0.029,H,A,1.04,0.34,2.886,,63.26,PHB,-2.559,0.100394,0.00515054,1.07112 kka2_1:8_A255F,kka2_1:8_255,Kka2,kka2_1:8,P00552,1.07112,NO,255,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.715,-3.34,1.625,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.100394,0.0126809,1.07112 kka2_1:8_A255F,kka2_1:8_255,Kka2,kka2_1:8,P00552,1.07112,NO,255,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.715,-3.34,1.625,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.100394,0.0126809,1.07112 gb1_D266N,gb1_266,gb1,gb1,P06654,1.07114,NO,266,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.261,-3.214,1.953,,,,,,,0.638,,45.54,HAO,-1.59333,0.177985,0.00394694,1.07114 beta-lactamase_0_T193Y,beta-lactamase_0_193,TEM-1,beta-lactamase_0,P62593,1.07115,NO,193,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.914,-3.989,2.075,,0.439,H,a,0.22,0.33,11.546,11.546,63.99,HPO,-1.52133,0.0500837,0.00482669,1.07115 kka2_1:2_T146F,kka2_1:2_146,Kka2,kka2_1:2,P00552,1.07115,NO,146,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.978,-4.333,1.355,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.295029,0.00606474,1.07115 kka2_1:8_P12R,kka2_1:8_12,Kka2,kka2_1:8,P00552,1.07116,NO,12,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.853,-3.931,3.078,,,.,B,0.52,1.25,2.41,,48.11,POH,-1.80767,0.100394,0.00500011,1.07116 kka2_1:8_P12R,kka2_1:8_12,Kka2,kka2_1:8,P00552,1.07116,NO,12,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.853,-3.931,3.078,,,.,B,0.52,1.25,2.41,,48.11,POH,-1.80767,0.100394,0.00500011,1.07116 kka2_1:2_I141Q,kka2_1:2_141,Kka2,kka2_1:2,P00552,1.07118,NO,141,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.495,-4.325,2.83,,0.068,H,A,0.48,-0.01,0.819,,92.05,BHA,-1.689,0.295029,0.00744745,1.07118 beta-lactamase_39_V106R,beta-lactamase_39_106,TEM-1,beta-lactamase_39,P62593,1.0712,NO,106,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.218,-4.201,2.983,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.0495842,0.00304168,1.0712 beta-lactamase_39_T138K,beta-lactamase_39_138,TEM-1,beta-lactamase_39,P62593,1.07121,NO,138,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.506,-2.186,-0.32,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.0495842,0.00487868,1.07121 beta-lactamase_39_A211H,beta-lactamase_39_211,TEM-1,beta-lactamase_39,P62593,1.07125,NO,211,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.896,-3.336,1.44,,0.369,T,A,0.46,-0.69,1.419,,77.62,AHA,-1.94633,0.0495842,0.00648183,1.07125 kka2_1:4_L152V,kka2_1:4_152,Kka2,kka2_1:4,P00552,1.07126,NO,152,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.521,-2.421,0.9,,0.547,,A,1.59,1.36,2.318,,63.64,OHH,-1.162,0.168804,0.00674868,1.07126 kka2_1:8_P128L,kka2_1:8_128,Kka2,kka2_1:8,P00552,1.07129,NO,128,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.922,-2.383,0.461,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.100394,0.00774689,1.07129 kka2_1:8_P128L,kka2_1:8_128,Kka2,kka2_1:8,P00552,1.07129,NO,128,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.922,-2.383,0.461,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.100394,0.00774689,1.07129 beta-lactamase_625_E272A,beta-lactamase_625_272,TEM-1,beta-lactamase_625,P62593,1.07135,NO,272,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.213352,0.00545371,1.07135 gb1_E245K,gb1_245,gb1,gb1,P06654,1.07135,NO,245,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.725,-1.265,-1.46,,,,,,,0.712,,45.54,PAH,-1.84567,0.177985,0.00158611,1.07135 beta-lactamase_0_G39Y,beta-lactamase_0_39,TEM-1,beta-lactamase_0,P62593,1.07137,NO,39,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.864,-4.383,2.519,,0.701,T,L,0.29,0.47,4.111,,77.62,HOH,-1.53633,0.0500837,0.00487611,1.07137 kka2_1:8_E231T,kka2_1:8_231,Kka2,kka2_1:8,P00552,1.07143,NO,231,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.002,-3.44,1.438,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.100394,0.00732383,1.07143 kka2_1:8_E231T,kka2_1:8_231,Kka2,kka2_1:8,P00552,1.07143,NO,231,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.002,-3.44,1.438,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.100394,0.00732383,1.07143 beta-lactamase_0_E166S,beta-lactamase_0_166,TEM-1,beta-lactamase_0,P62593,1.07145,NO,166,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.756,-2.582,0.826,,0.508,G,A,1.04,1.05,17.227,17.227,73.08,OAH,-1.42233,0.0500837,0.00512989,1.07145 beta-lactamase_625_E272D,beta-lactamase_625_272,TEM-1,beta-lactamase_625,P62593,1.07146,NO,272,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.213352,0.00545371,1.07146 beta-lactamase_0_L49F,beta-lactamase_0_49,TEM-1,beta-lactamase_0,P62593,1.07147,NO,49,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.897,-3.092,1.195,,0.131,T,A,0.55,0.04,13.838,13.838,64.69,AHP,-1.99233,0.0500837,0.00401477,1.07147 PSD95pdz3_T387R,PSD95pdz3_387,PSD95pdz3,PSD95pdz3,P31016,1.07154,NO,387,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.391,-3.39,1.999,5.20757,,,,,18.8043,,,,HPH,-1.49533,0.0758425,0.000167911,1.07154 kka2_1:4_R239Y,kka2_1:4_239,Kka2,kka2_1:4,P00552,1.07157,NO,239,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.949,-4.327,1.378,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.168804,0.00835326,1.07157 beta-lactamase_39_W208Y,beta-lactamase_39_208,TEM-1,beta-lactamase_39,P62593,1.07166,NO,208,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-0.818,-3.262,2.444,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.0495842,0.00126609,1.07166 gb1_E245W,gb1_245,gb1,gb1,P06654,1.07166,NO,245,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.725,-5.058,2.333,,,,,,,0.712,,45.54,PAH,-1.84567,0.177985,0.00158611,1.07166 gb1_K276G,gb1_276,gb1,gb1,P06654,1.07166,NO,276,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.456,-3.198,1.742,,,,,,,0.236,,12.72,PBP,-1.65133,0.177985,0.00620493,1.07166 PSD95pdz3_I338L,PSD95pdz3_338,PSD95pdz3,PSD95pdz3,P31016,1.07166,NO,338,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.63,-2.14,0.51,5.45113,,,,,13.0087,,,,HHP,-1.55767,0.0758425,0.000862587,1.07166 WW_domain_V171A,WW_domain_171,Yap65,WW_domain,P46937,1.07166,NO,171,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.547,-2.085,0.538,,,,,,,3.459,,70.24,AHO,-1.265,0.153962,0.00184125,1.07166 kka2_1:2_A137K,kka2_1:2_137,Kka2,kka2_1:2,P00552,1.07167,NO,137,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.156,-3.751,1.595,,0.029,H,A,0.46,0.34,1.323,,63.26,PHB,-2.559,0.295029,0.00515054,1.07167 beta-lactamase_39_F149R,beta-lactamase_39_149,TEM-1,beta-lactamase_39,P62593,1.07168,NO,149,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.299,-4.139,2.84,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.0495842,0.00418462,1.07168 beta-lactamase_0_H24T,beta-lactamase_0_24,TEM-1,beta-lactamase_0,P62593,1.07174,NO,24,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-2.481,-2.645,0.164,,,,,,,2.708,,93.01,OBO,-2.0035,0.0500837,0.00238894,1.07174 gb1_D248E,gb1_248,gb1,gb1,P06654,1.07176,NO,248,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.569,-2.776,1.207,,,,,,,0.344,,11.83,HAH,-1.673,0.177985,0.001865,1.07176 gb1_E245F,gb1_245,gb1,gb1,P06654,1.07176,NO,245,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.725,-4.028,1.303,,,,,,,0.712,,45.54,PAH,-1.84567,0.177985,0.00158611,1.07176 kka2_1:8_G55Q,kka2_1:8_55,Kka2,kka2_1:8,P00552,1.07176,NO,55,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.625,-4.083,2.458,,0.517,S,b,0.29,1.19,8.881,,63.64,POH,-2.05967,0.100394,0.00667877,1.07176 kka2_1:8_G55Q,kka2_1:8_55,Kka2,kka2_1:8,P00552,1.07176,NO,55,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.625,-4.083,2.458,,0.517,S,b,0.29,1.19,8.881,,63.64,POH,-2.05967,0.100394,0.00667877,1.07176 PSD95pdz3_L360K,PSD95pdz3_360,PSD95pdz3,PSD95pdz3,P31016,1.07181,NO,360,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.431,-3.363,1.932,5.09284,,,,,14.2425,1.419,,86.88,HHP,-1.52667,0.0758425,0.000770471,1.07181 beta-lactamase_0_E279A,beta-lactamase_0_279,TEM-1,beta-lactamase_0,P62593,1.07182,NO,279,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.0500837,0.0192826,1.07182 kka2_1:4_P132M,kka2_1:4_132,Kka2,kka2_1:4,P00552,1.07182,NO,132,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.775,-4.731,3.956,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.168804,0.0018489,1.07182 beta-lactamase_0_L192M,beta-lactamase_0_192,TEM-1,beta-lactamase_0,P62593,1.07183,NO,192,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.254,-4.084,2.83,,0.095,H,A,0.55,0.35,1.756,,60.14,HHP,-1.41833,0.0500837,0.00558728,1.07183 beta-lactamase_625_E272I,beta-lactamase_625_272,TEM-1,beta-lactamase_625,P62593,1.07186,NO,272,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.213352,0.00545371,1.07186 kka2_1:4_I254F,kka2_1:4_254,Kka2,kka2_1:4,P00552,1.07186,NO,254,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.933,-3.851,1.918,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.168804,0.0132375,1.07186 kka2_1:8_Q42M,kka2_1:8_42,Kka2,kka2_1:8,P00552,1.07189,NO,42,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.907,-4.883,1.976,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.100394,0.00679212,1.07189 kka2_1:8_Q42M,kka2_1:8_42,Kka2,kka2_1:8,P00552,1.07189,NO,42,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.907,-4.883,1.976,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.100394,0.00679212,1.07189 beta-lactamase_0_S80Q,beta-lactamase_0_80,TEM-1,beta-lactamase_0,P62593,1.07192,NO,80,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.029,-3.941,1.912,,0.192,H,A,0.27,0.46,12.403,12.403,77.62,HPB,-1.44567,0.0500837,0.00565569,1.07192 beta-lactamase_156_D212N,beta-lactamase_156_212,TEM-1,beta-lactamase_156,P62593,1.07196,NO,212,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.624,-1.899,0.275,,0.037,,b,0.75,-0.58,20.222,20.222,74.48,HAB,-1.77667,0.111618,0.00644302,1.07196 beta-lactamase_0_I140W,beta-lactamase_0_140,TEM-1,beta-lactamase_0,P62593,1.07197,NO,140,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.733,-5.289,3.556,,0.128,H,A,0.48,0.41,4.714,,73.08,PHO,-1.48733,0.0500837,0.00597777,1.07197 gb1_D272T,gb1_272,gb1,gb1,P06654,1.07197,NO,272,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.457,-3.226,1.769,,,,,,,0.234,,11.83,HAA,-1.54533,0.177985,0.00218257,1.07197 PSD95pdz3_G319N,PSD95pdz3_319,PSD95pdz3,PSD95pdz3,P31016,1.07205,NO,319,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.008,-3.13,2.122,4.95387,,,,,18.8725,,,,BOP,-1.36967,0.0758425,0.00109317,1.07205 beta-lactamase_39_R41K,beta-lactamase_39_41,TEM-1,beta-lactamase_39,P62593,1.07211,NO,41,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-0.942,-2.85,1.908,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.0495842,0.00123327,1.07211 kka2_1:2_L47I,kka2_1:2_47,Kka2,kka2_1:2,P00552,1.07211,NO,47,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.265,-3.255,1.99,,0.139,E,B,0.55,-0.86,2.369,,63.26,HHH,-1.77933,0.295029,0.00509386,1.07211 kka2_1:8_T28C,kka2_1:8_28,Kka2,kka2_1:8,P00552,1.07213,NO,28,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.883,-5.036,3.153,,0.353,S,B,0.22,2.02,18.114,18.114,63.64,PPH,-1.74467,0.100394,0.00743084,1.07213 kka2_1:8_T28C,kka2_1:8_28,Kka2,kka2_1:8,P00552,1.07213,NO,28,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.883,-5.036,3.153,,0.353,S,B,0.22,2.02,18.114,18.114,63.64,PPH,-1.74467,0.100394,0.00743084,1.07213 beta-lactamase_39_M209S,beta-lactamase_39_209,TEM-1,beta-lactamase_39,P62593,1.07217,NO,209,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.442,-3.579,2.137,,,H,A,0.55,-0.97,1.167,,64.69,HHA,-1.52633,0.0495842,0.00625021,1.07217 kka2_1:8_A222G,kka2_1:8_222,Kka2,kka2_1:8,P00552,1.07219,NO,222,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.725,-2.936,2.211,,,H,A,1.04,-1.21,,,,HHH,-1.10833,0.100394,0.00207657,1.07219 kka2_1:8_A222G,kka2_1:8_222,Kka2,kka2_1:8,P00552,1.07219,NO,222,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.725,-2.936,2.211,,,H,A,1.04,-1.21,,,,HHH,-1.10833,0.100394,0.00207657,1.07219 beta-lactamase_0_H156C,beta-lactamase_0_156,TEM-1,beta-lactamase_0,P62593,1.0722,NO,156,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-3.156,-5.208,2.052,,0.753,S,A,0.17,-0.6,23.367,23.367,77.62,ABH,-1.932,0.0500837,0.00468596,1.0722 beta-lactamase_0_L167T,beta-lactamase_0_167,TEM-1,beta-lactamase_0,P62593,1.07226,NO,167,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.138,-3.44,2.302,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.0500837,0.00303566,1.07226 beta-lactamase_0_S104W,beta-lactamase_0_104,TEM-1,beta-lactamase_0,P62593,1.07227,NO,104,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.015,-5.359,4.344,,0.04,,b,0.27,0.57,1.148,,63.29,HPO,-1.05267,0.0500837,0.00218083,1.07227 gb1_E268G,gb1_268,gb1,gb1,P06654,1.07228,NO,268,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.918,-3.18,1.262,,,,,,,0.637,,37.28,OAH,-1.59733,0.177985,0.00423953,1.07228 gb1_E268Y,gb1_268,gb1,gb1,P06654,1.07228,NO,268,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.918,-4.081,2.163,,,,,,,0.637,,37.28,OAH,-1.59733,0.177985,0.00423953,1.07228 beta-lactamase_0_G281V,beta-lactamase_0_281,TEM-1,beta-lactamase_0,P62593,1.07229,NO,281,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.0500837,0.0406482,1.07229 beta-lactamase_39_V214R,beta-lactamase_39_214,TEM-1,beta-lactamase_39,P62593,1.07231,NO,214,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.299,-4.047,2.748,,0.375,S,A,0.44,-0.44,18.838,18.838,74.48,BHH,-1.53733,0.0495842,0.00628442,1.07231 PSD95pdz3_R313V,PSD95pdz3_313,PSD95pdz3,PSD95pdz3,P31016,1.07232,NO,313,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.582,-3.435,1.853,6.63563,,,,,18.3955,,,,BBH,-1.59733,0.0758425,0.000840067,1.07232 kka2_1:8_M148S,kka2_1:8_148,Kka2,kka2_1:8,P00552,1.07236,NO,148,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.847,-3.618,1.771,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.100394,0.00982664,1.07236 kka2_1:8_M148S,kka2_1:8_148,Kka2,kka2_1:8,P00552,1.07236,NO,148,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.847,-3.618,1.771,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.100394,0.00982664,1.07236 kka2_1:4_I254G,kka2_1:4_254,Kka2,kka2_1:4,P00552,1.07239,NO,254,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.933,-3.809,1.876,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.168804,0.0132375,1.07239 PSD95pdz3_S320I,PSD95pdz3_320,PSD95pdz3,PSD95pdz3,P31016,1.0724,NO,320,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.519,-3.467,1.948,5.81757,,,,,21.4517,,,,OPP,-1.306,0.0758425,0.00108158,1.0724 beta-lactamase_0_T269P,beta-lactamase_0_269,TEM-1,beta-lactamase_0,P62593,1.07241,NO,269,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.0500837,0.00950944,1.07241 kka2_1:2_A87D,kka2_1:2_87,Kka2,kka2_1:2,P00552,1.07241,NO,87,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.917,-2.332,0.415,,1.039,S,L,0.46,1.57,22.675,22.675,65.53,AHO,-1.822,0.295029,0.00791281,1.07241 beta-lactamase_0_H24F,beta-lactamase_0_24,TEM-1,beta-lactamase_0,P62593,1.07244,NO,24,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-2.481,-4.152,1.671,,,,,,,2.708,,93.01,OBO,-2.0035,0.0500837,0.00238894,1.07244 beta-lactamase_A15Y,beta-lactamase_15,TEM-1,beta-lactamase,P62593,1.07246,NO,15,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.654,-4.17,2.516,,,,,,,31.998,31.998,93.01,HHH,-2.10833,0.221079,0.00248966,1.07246 kka2_1:4_R253A,kka2_1:4_253,Kka2,kka2_1:4,P00552,1.07246,NO,253,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.356,-2.382,1.026,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.168804,0.0144195,1.07246 kka2_1:8_P12D,kka2_1:8_12,Kka2,kka2_1:8,P00552,1.07246,NO,12,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.853,-3.54,2.687,,,.,B,0.52,1.25,2.41,,48.11,POH,-1.80767,0.100394,0.00500011,1.07246 kka2_1:8_P12D,kka2_1:8_12,Kka2,kka2_1:8,P00552,1.07246,NO,12,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.853,-3.54,2.687,,,.,B,0.52,1.25,2.41,,48.11,POH,-1.80767,0.100394,0.00500011,1.07246 beta-lactamase_0_E102Q,beta-lactamase_0_102,TEM-1,beta-lactamase_0,P62593,1.07249,NO,102,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.118,-3.043,0.925,,0.722,S,B,1.04,1.82,4.773,,73.08,HAH,-1.581,0.0500837,0.00486633,1.07249 kka2_1:2_H8I,kka2_1:2_8,Kka2,kka2_1:2,P00552,1.07256,NO,8,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-2.759,-2.602,-0.157,,,,,,,,,71.59,HBH,-2.25467,0.295029,0.00256422,1.07256 beta-lactamase_0_Q267D,beta-lactamase_0_267,TEM-1,beta-lactamase_0,P62593,1.07259,NO,267,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.0500837,0.0102128,1.07259 kka2_1:4_L165S,kka2_1:4_165,Kka2,kka2_1:4,P00552,1.07259,NO,165,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-2.453,-3.581,1.128,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.168804,0.00801161,1.07259 kka2_1:4_A110I,kka2_1:4_110,Kka2,kka2_1:4,P00552,1.07263,NO,110,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.064,-3.899,1.835,,0.175,H,A,0.46,-1.19,23.237,23.237,71.59,OHA,-1.91867,0.168804,0.00759851,1.07263 kka2_1:4_P249F,kka2_1:4_249,Kka2,kka2_1:4,P00552,1.07265,NO,249,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.867,-3.04,1.173,,0.406,.,B,0.52,-0.01,,,92.05,HOA,-1.66867,0.168804,0.011045,1.07265 beta-lactamase_0_G114S,beta-lactamase_0_114,TEM-1,beta-lactamase_0,P62593,1.07267,NO,114,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.094,-2.588,1.494,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.0500837,0.00224919,1.07267 beta-lactamase_625_M127D,beta-lactamase_625_127,TEM-1,beta-lactamase_625,P62593,1.07269,NO,127,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-2.251,-3.966,1.715,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.213352,0.00437927,1.07269 Pab1_P200Q,Pab1_200,Pab1,Pab1,P04147,1.07269,NO,200,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.871,-2.717,0.846,,,,,,,3.877,,80.59,HOO,-1.7005,0.175299,0.00190795,1.07269 kka2_1:8_S104Q,kka2_1:8_104,Kka2,kka2_1:8,P00552,1.07271,NO,104,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.436,-3.082,1.646,,0.536,T,A,0.27,-1.11,1.689,,63.64,HPP,-1.91433,0.100394,0.00555207,1.07271 kka2_1:8_S104Q,kka2_1:8_104,Kka2,kka2_1:8,P00552,1.07271,NO,104,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.436,-3.082,1.646,,0.536,T,A,0.27,-1.11,1.689,,63.64,HPP,-1.91433,0.100394,0.00555207,1.07271 beta-lactamase_0_D33M,beta-lactamase_0_33,TEM-1,beta-lactamase_0,P62593,1.07279,NO,33,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.321,-4.607,2.286,,0.366,H,A,0.75,0.33,12.514,12.514,77.62,BAH,-2.12133,0.0500837,0.00435556,1.07279 kka2_1:8_L7Y,kka2_1:8_7,Kka2,kka2_1:8,P00552,1.07282,NO,7,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.926,-3.823,1.897,,,,,,,,,71.59,OHB,-2.12333,0.100394,0.00269456,1.07282 kka2_1:8_L7Y,kka2_1:8_7,Kka2,kka2_1:8,P00552,1.07282,NO,7,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.926,-3.823,1.897,,,,,,,,,71.59,OHB,-2.12333,0.100394,0.00269456,1.07282 kka2_1:4_D180W,kka2_1:4_180,Kka2,kka2_1:4,P00552,1.07283,NO,180,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.416,-5.59,3.174,,1.03,S,a,0.29,1.5,14.668,14.668,71.59,OAO,-2.02933,0.168804,0.00756412,1.07283 kka2_1:8_D227Q,kka2_1:8_227,Kka2,kka2_1:8,P00552,1.07284,NO,227,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.758,-3.747,1.989,,0.128,H,A,0.75,-0.63,0.281,,56.06,BAH,-1.43067,0.100394,0.00745029,1.07284 kka2_1:8_D227Q,kka2_1:8_227,Kka2,kka2_1:8,P00552,1.07284,NO,227,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.758,-3.747,1.989,,0.128,H,A,0.75,-0.63,0.281,,56.06,BAH,-1.43067,0.100394,0.00745029,1.07284 PSD95pdz3_G344C,PSD95pdz3_344,PSD95pdz3,PSD95pdz3,P31016,1.07287,NO,344,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.008,-4.769,3.761,4.83855,,,,,14.06,,,,HOO,-1.10767,0.0758425,0.00078498,1.07287 PSD95pdz3_P311E,PSD95pdz3_311,PSD95pdz3,PSD95pdz3,P31016,1.07287,NO,311,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.236,-3.122,1.886,5.76649,,,,,14.78,,,,OOB,-1.409,0.0758425,0.0030796,1.07287 kka2_1:8_D33L,kka2_1:8_33,Kka2,kka2_1:8,P00552,1.07294,NO,33,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.186,-3.734,1.548,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.100394,0.00633568,1.07294 kka2_1:8_D33L,kka2_1:8_33,Kka2,kka2_1:8,P00552,1.07294,NO,33,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.186,-3.734,1.548,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.100394,0.00633568,1.07294 kka2_1:2_Q4A,kka2_1:2_4,Kka2,kka2_1:2,P00552,1.07299,NO,4,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.361,-2.857,0.496,,,,,,,2.026,,71.59,APA,-1.95533,0.295029,0.00239179,1.07299 beta-lactamase_39_R59F,beta-lactamase_39_59,TEM-1,beta-lactamase_39,P62593,1.07304,NO,59,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.345,-4.379,3.034,,0.329,S,L,1.2,-0.09,1.806,,73.08,HBO,-2.24267,0.0495842,0.00318082,1.07304 kka2_1:8_R44V,kka2_1:8_44,Kka2,kka2_1:8,P00552,1.07306,NO,44,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.062,-3.733,1.671,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.100394,0.00745043,1.07306 kka2_1:8_R44V,kka2_1:8_44,Kka2,kka2_1:8,P00552,1.07306,NO,44,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.062,-3.733,1.671,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.100394,0.00745043,1.07306 kka2_1:4_L212M,kka2_1:4_212,Kka2,kka2_1:4,P00552,1.07307,NO,212,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.904,-3.974,3.07,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.168804,0.0031426,1.07307 gb1_D248Q,gb1_248,gb1,gb1,P06654,1.07309,NO,248,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.569,-3.485,1.916,,,,,,,0.344,,11.83,HAH,-1.673,0.177985,0.001865,1.07309 kka2_1:4_D157A,kka2_1:4_157,Kka2,kka2_1:4,P00552,1.07309,NO,157,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.993,-3.298,2.305,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.168804,0.0042313,1.07309 kka2_1:8_G99E,kka2_1:8_99,Kka2,kka2_1:8,P00552,1.07311,NO,99,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.596,-3.693,3.097,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.100394,0.00186055,1.07311 kka2_1:8_G99E,kka2_1:8_99,Kka2,kka2_1:8,P00552,1.07311,NO,99,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.596,-3.693,3.097,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.100394,0.00186055,1.07311 PSD95pdz3_H317Q,PSD95pdz3_317,PSD95pdz3,PSD95pdz3,P31016,1.07314,NO,317,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-1.627,-3.356,1.729,6.19713,,,,,25.885,,,,HBB,-1.613,0.0758425,0.00111619,1.07314 beta-lactamase_0_M67N,beta-lactamase_0_67,TEM-1,beta-lactamase_0,P62593,1.07316,NO,67,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-2.231,-2.235,0.004,,0.006,G,P,0.55,-0.81,24.165,24.165,65.03,HHP,-1.502,0.0500837,0.00409753,1.07316 kka2_1:4_N200Q,kka2_1:4_200,Kka2,kka2_1:4,P00552,1.07316,NO,200,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-2.446,-2.857,0.411,,0.756,T,L,0.61,-0.08,1.746,,64.39,APO,-2.08,0.168804,0.00838549,1.07316 gb1_K236R,gb1_236,gb1,gb1,P06654,1.0732,NO,236,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-2.119,-3.242,1.123,,,,,,,1.083,,45.54,OBP,-1.758,0.177985,0.00255408,1.0732 beta-lactamase_39_H110S,beta-lactamase_39_110,TEM-1,beta-lactamase_39,P62593,1.07322,NO,110,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-1.706,-3.537,1.831,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.0495842,0.00441499,1.07322 kka2_1:2_R143S,kka2_1:2_143,Kka2,kka2_1:2,P00552,1.07328,NO,143,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.525,-3.022,0.497,,0.325,H,A,0.16,1.22,14.853,14.853,65.53,ABH,-1.86833,0.295029,0.00662247,1.07328 gb1_E245V,gb1_245,gb1,gb1,P06654,1.0733,NO,245,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.725,-3.264,0.539,,,,,,,0.712,,45.54,PAH,-1.84567,0.177985,0.00158611,1.0733 kka2_1:8_I29V,kka2_1:8_29,Kka2,kka2_1:8,P00552,1.07335,NO,29,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.692,-2.359,0.667,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.100394,0.00619521,1.07335 kka2_1:8_I29V,kka2_1:8_29,Kka2,kka2_1:8,P00552,1.07335,NO,29,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.692,-2.359,0.667,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.100394,0.00619521,1.07335 beta-lactamase_0_E166K,beta-lactamase_0_166,TEM-1,beta-lactamase_0,P62593,1.07337,NO,166,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.756,-2.625,0.869,,0.508,G,A,1.04,1.05,17.227,17.227,73.08,OAH,-1.42233,0.0500837,0.00512989,1.07337 kka2_1:8_G10V,kka2_1:8_10,Kka2,kka2_1:8,P00552,1.07338,NO,10,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.921,-3.683,1.762,,,,,,,1.862,,71.59,HOP,-2.10733,0.100394,0.00289233,1.07338 kka2_1:8_G10V,kka2_1:8_10,Kka2,kka2_1:8,P00552,1.07338,NO,10,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.921,-3.683,1.762,,,,,,,1.862,,71.59,HOP,-2.10733,0.100394,0.00289233,1.07338 gb1_Y259F,gb1_259,gb1,gb1,P06654,1.0734,NO,259,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-1.78,-1.813,0.033,,,,,,,0.131,,11.83,PHH,-1.787,0.177985,0.00464313,1.0734 beta-lactamase_0_N152V,beta-lactamase_0_152,TEM-1,beta-lactamase_0,P62593,1.07341,NO,152,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-2.757,-3.616,0.859,,0.863,H,A,0.61,0.92,2.151,,77.62,BPH,-2.97,0.0500837,0.00471429,1.07341 PSD95pdz3_I316F,PSD95pdz3_316,PSD95pdz3,PSD95pdz3,P31016,1.07346,NO,316,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.63,-3.299,1.669,5.46166,,,,,19.005,,,,HHB,-1.62733,0.0758425,0.00112762,1.07346 kka2_1:1_F20Q,kka2_1:1_20,Kka2,kka2_1:1,P00552,1.07349,NO,20,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-3.354,-3.237,-0.117,,0.935,T,B,0.58,-0.41,1.657,,92.05,HHO,-1.992,0.520039,0.00701744,1.07349 gb1_D273G,gb1_273,gb1,gb1,P06654,1.0735,NO,273,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.998,-3.111,1.113,,,,,,,3.514,3.514,37.28,AAH,-1.72767,0.177985,0.00318903,1.0735 kka2_1:4_V75N,kka2_1:4_75,Kka2,kka2_1:4,P00552,1.07352,NO,75,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-2.06,-4.176,2.116,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.168804,0.00693733,1.07352 beta-lactamase_0_I261Y,beta-lactamase_0_261,TEM-1,beta-lactamase_0,P62593,1.07355,NO,261,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.0500837,0.0123091,1.07355 beta-lactamase_0_R239Y,beta-lactamase_0_239,TEM-1,beta-lactamase_0,P62593,1.07357,NO,239,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.0500837,0.00213852,1.07357 kka2_1:8_S105Q,kka2_1:8_105,Kka2,kka2_1:8,P00552,1.07357,NO,105,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.945,-3.245,1.3,,0.056,S,B,0.27,-1.04,2.115,,65.53,PPB,-2.17033,0.100394,0.00847233,1.07357 kka2_1:8_S105Q,kka2_1:8_105,Kka2,kka2_1:8,P00552,1.07357,NO,105,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.945,-3.245,1.3,,0.056,S,B,0.27,-1.04,2.115,,65.53,PPB,-2.17033,0.100394,0.00847233,1.07357 beta-lactamase_0_A170W,beta-lactamase_0_170,TEM-1,beta-lactamase_0,P62593,1.07359,NO,170,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.237,-5.233,3.996,,0.126,,L,0.46,-0.35,2.427,,64.69,AHH,-1.63267,0.0500837,0.00431903,1.07359 kka2_1:4_P128A,kka2_1:4_128,Kka2,kka2_1:4,P00552,1.0736,NO,128,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.922,-2.593,0.671,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.168804,0.00774689,1.0736 kka2_1:4_L81M,kka2_1:4_81,Kka2,kka2_1:4,P00552,1.07363,NO,81,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.427,-2.896,1.469,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.168804,0.00805839,1.07363 WW_domain_S184R,WW_domain_184,Yap65,WW_domain,P46937,1.07363,NO,184,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.363,-3.548,2.185,5.06696,,,,,,,,,PPO,-1.39133,0.153962,0.00231095,1.07363 kka2_1:4_R145Q,kka2_1:4_145,Kka2,kka2_1:4,P00552,1.07365,NO,145,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.804,-2.583,0.779,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.168804,0.00846663,1.07365 beta-lactamase_0_A84V,beta-lactamase_0_84,TEM-1,beta-lactamase_0,P62593,1.07367,NO,84,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.651,-2.943,1.292,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.0500837,0.00503822,1.07367 beta-lactamase_0_Q37T,beta-lactamase_0_37,TEM-1,beta-lactamase_0,P62593,1.07372,NO,37,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.134,-2.508,0.374,,0.613,H,A,0.64,1.98,4.001,,73.08,APH,-2.06967,0.0500837,0.00425833,1.07372 PSD95pdz3_E334A,PSD95pdz3_334,PSD95pdz3,PSD95pdz3,P31016,1.07373,NO,334,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.404,-2.759,1.355,5.60175,,,,,53.09,,,,OAO,-1.14,0.0758425,0.000912998,1.07373 beta-lactamase_0_A278D,beta-lactamase_0_278,TEM-1,beta-lactamase_0,P62593,1.07374,NO,278,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.348,,,,0.015,H,A,0.48,-0.85,4.624,,63.29,HHA,-1.41833,0.0500837,0.0310297,1.07374 kka2_1:2_Q26W,kka2_1:2_26,Kka2,kka2_1:2,P00552,1.07374,NO,26,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.18,-5.501,3.321,,0.448,E,B,0.4,0.44,5.022,,92.05,HPP,-2.11167,0.295029,0.00708962,1.07374 beta-lactamase_0_T116L,beta-lactamase_0_116,TEM-1,beta-lactamase_0,P62593,1.07378,NO,116,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.28,-3.376,2.096,,0.115,E,B,0.22,-0.12,1.356,,67.48,HPH,-1.39967,0.0500837,0.00336175,1.07378 PSD95pdz3_P311V,PSD95pdz3_311,PSD95pdz3,PSD95pdz3,P31016,1.07379,NO,311,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.236,-3.21,1.974,5.76649,,,,,14.78,,,,OOB,-1.409,0.0758425,0.0030796,1.07379 gb1_N234Y,gb1_234,gb1,gb1,P06654,1.07381,NO,234,N,Y,NY,Polar,Hydrophobic,5.47157,5.66,0.188425,143,132,181,49,114.1,193.6,79.5,-2.055,-4.003,1.948,,,,,,,1.235,,45.54,HPO,-2.05067,0.177985,0.00242189,1.07381 kka2_1:4_Q61K,kka2_1:4_61,Kka2,kka2_1:4,P00552,1.07383,NO,61,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.982,-3.601,0.619,,0.591,H,A,0.64,0.41,3.484,,65.53,HPA,-1.85667,0.168804,0.00612092,1.07383 kka2_1:2_D250E,kka2_1:2_250,Kka2,kka2_1:2,P00552,1.07384,NO,250,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.015,-2.129,1.114,,0.274,.,b,0.75,-0.46,3.796,,51.89,OAP,-1.83933,0.295029,0.0177103,1.07384 kka2_1:4_A14S,kka2_1:4_14,Kka2,kka2_1:4,P00552,1.07384,NO,14,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.837,-2.532,0.695,,0.728,G,A,0.46,0.7,0.36,,71.59,HHH,-1.82567,0.168804,0.00706614,1.07384 beta-lactamase_39_H110D,beta-lactamase_39_110,TEM-1,beta-lactamase_39,P62593,1.074,NO,110,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-1.706,-3.678,1.972,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.0495842,0.00441499,1.074 gb1_T277F,gb1_277,gb1,gb1,P06654,1.07401,NO,277,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.771,-4.004,2.233,,,,,,,0.824,,35.71,BPH,-1.54833,0.177985,0.00348258,1.07401 beta-lactamase_0_T131W,beta-lactamase_0_131,TEM-1,beta-lactamase_0,P62593,1.07405,NO,131,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.328,-5.315,3.987,,,H,A,0.22,-0.69,3.306,,67.48,PPH,-1.00867,0.0500837,0.00345886,1.07405 kka2_1:4_A56V,kka2_1:4_56,Kka2,kka2_1:4,P00552,1.07405,NO,56,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.083,-2.653,0.57,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.168804,0.00717715,1.07405 kka2_1:8_D156C,kka2_1:8_156,Kka2,kka2_1:8,P00552,1.0741,NO,156,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.696,-3.452,1.756,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.100394,0.00926998,1.0741 kka2_1:8_D156C,kka2_1:8_156,Kka2,kka2_1:8,P00552,1.0741,NO,156,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.696,-3.452,1.756,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.100394,0.00926998,1.0741 gb1_E245I,gb1_245,gb1,gb1,P06654,1.07411,NO,245,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.725,-3.746,1.021,,,,,,,0.712,,45.54,PAH,-1.84567,0.177985,0.00158611,1.07411 kka2_1:2_E161D,kka2_1:2_161,Kka2,kka2_1:2,P00552,1.07414,NO,161,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.581,-2.26,0.679,,0.829,G,A,1.52,2.24,1.612,,92.05,AAB,-1.861,0.295029,0.00760103,1.07414 kka2_1:8_Q163H,kka2_1:8_163,Kka2,kka2_1:8,P00552,1.0742,NO,163,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.162,-4.775,2.613,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.100394,0.00719507,1.0742 kka2_1:8_Q163H,kka2_1:8_163,Kka2,kka2_1:8,P00552,1.0742,NO,163,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.162,-4.775,2.613,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.100394,0.00719507,1.0742 gb1_D266C,gb1_266,gb1,gb1,P06654,1.07421,NO,266,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.261,-4.858,3.597,,,,,,,0.638,,45.54,HAO,-1.59333,0.177985,0.00394694,1.07421 beta-lactamase_0_L223M,beta-lactamase_0_223,TEM-1,beta-lactamase_0,P62593,1.07422,NO,223,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.055,-3.986,2.931,,0.27,,B,0.55,0.09,1.633,,74.48,HHO,-1.35033,0.0500837,0.00372793,1.07422 beta-lactamase_0_N98D,beta-lactamase_0_98,TEM-1,beta-lactamase_0,P62593,1.07422,NO,98,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-2.973,-2.35,-0.623,,0.963,G,A,0.61,1.35,14.853,14.853,77.62,PPA,-2.07867,0.0500837,0.00505389,1.07422 beta-lactamase_39_I171G,beta-lactamase_39_171,TEM-1,beta-lactamase_39,P62593,1.07422,NO,171,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-2.431,-3.603,1.172,,0.361,,B,0.48,0.53,16.954,16.954,77.62,HHO,-1.55533,0.0495842,0.00623355,1.07422 beta-lactamase_39_S80E,beta-lactamase_39_80,TEM-1,beta-lactamase_39,P62593,1.07429,NO,80,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.029,-2.666,0.637,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.0495842,0.00565569,1.07429 beta-lactamase_0_T269R,beta-lactamase_0_269,TEM-1,beta-lactamase_0,P62593,1.07431,NO,269,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.0500837,0.00950944,1.07431 kka2_1:8_D52F,kka2_1:8_52,Kka2,kka2_1:8,P00552,1.07433,NO,52,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.271,-4.344,2.073,,0.22,E,B,0.75,0.8,5.447,,71.59,PAH,-2.38367,0.100394,0.00175694,1.07433 kka2_1:8_D52F,kka2_1:8_52,Kka2,kka2_1:8,P00552,1.07433,NO,52,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.271,-4.344,2.073,,0.22,E,B,0.75,0.8,5.447,,71.59,PAH,-2.38367,0.100394,0.00175694,1.07433 PSD95pdz3_T321V,PSD95pdz3_321,PSD95pdz3,PSD95pdz3,P31016,1.07434,NO,321,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.391,-2.76,1.369,5.19953,,,,,20.3371,,,,PPO,-1.306,0.0758425,0.00106992,1.07434 kka2_1:4_P76T,kka2_1:4_76,Kka2,kka2_1:4,P00552,1.07435,NO,76,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.449,-2.904,1.455,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.168804,0.00625685,1.07435 kka2_1:8_R145A,kka2_1:8_145,Kka2,kka2_1:8,P00552,1.07436,NO,145,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.804,-2.368,0.564,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.100394,0.00846663,1.07436 kka2_1:8_R145A,kka2_1:8_145,Kka2,kka2_1:8,P00552,1.07436,NO,145,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.804,-2.368,0.564,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.100394,0.00846663,1.07436 kka2_1:2_A87F,kka2_1:2_87,Kka2,kka2_1:2,P00552,1.07439,NO,87,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.917,-4.449,2.532,,1.039,S,L,0.46,1.57,22.675,22.675,65.53,AHO,-1.822,0.295029,0.00791281,1.07439 beta-lactamase_0_H110Q,beta-lactamase_0_110,TEM-1,beta-lactamase_0,P62593,1.0744,NO,110,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-1.706,-2.734,1.028,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.0500837,0.00441499,1.0744 kka2_1:8_V36T,kka2_1:8_36,Kka2,kka2_1:8,P00552,1.07443,NO,36,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-0.898,-3.307,2.409,,0.292,E,B,1.48,0.21,0.938,,52.27,HHH,-1.484,0.100394,0.00245633,1.07443 kka2_1:8_V36T,kka2_1:8_36,Kka2,kka2_1:8,P00552,1.07443,NO,36,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-0.898,-3.307,2.409,,0.292,E,B,1.48,0.21,0.938,,52.27,HHH,-1.484,0.100394,0.00245633,1.07443 kka2_1:2_Q4R,kka2_1:2_4,Kka2,kka2_1:2,P00552,1.07448,NO,4,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.361,-3.443,1.082,,,,,,,2.026,,71.59,APA,-1.95533,0.295029,0.00239179,1.07448 kka2_1:4_E230Q,kka2_1:4_230,Kka2,kka2_1:4,P00552,1.0746,NO,230,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.672,-4.02,1.348,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.168804,0.00920051,1.0746 kka2_1:8_A87D,kka2_1:8_87,Kka2,kka2_1:8,P00552,1.07461,NO,87,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.917,-2.332,0.415,,1.039,S,L,0.46,1.57,16.115,16.115,65.53,AHO,-1.822,0.100394,0.00791281,1.07461 kka2_1:8_A87D,kka2_1:8_87,Kka2,kka2_1:8,P00552,1.07461,NO,87,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.917,-2.332,0.415,,1.039,S,L,0.46,1.57,16.115,16.115,65.53,AHO,-1.822,0.100394,0.00791281,1.07461 kka2_1:4_E231L,kka2_1:4_231,Kka2,kka2_1:4,P00552,1.07463,NO,231,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.002,-3.642,1.64,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.168804,0.00732383,1.07463 kka2_1:4_L165M,kka2_1:4_165,Kka2,kka2_1:4,P00552,1.07463,NO,165,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-2.453,-2.818,0.365,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.168804,0.00801161,1.07463 beta-lactamase_0_T112E,beta-lactamase_0_112,TEM-1,beta-lactamase_0,P62593,1.07465,NO,112,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.186,-2.494,0.308,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.0500837,0.00531334,1.07465 kka2_1:8_E160W,kka2_1:8_160,Kka2,kka2_1:8,P00552,1.07465,NO,160,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.683,-5.621,3.938,,0.989,G,A,1.04,2.28,2.164,,71.59,AAA,-1.36133,0.100394,0.00935762,1.07465 kka2_1:8_E160W,kka2_1:8_160,Kka2,kka2_1:8,P00552,1.07465,NO,160,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.683,-5.621,3.938,,0.989,G,A,1.04,2.28,2.164,,71.59,AAA,-1.36133,0.100394,0.00935762,1.07465 kka2_1:8_D52A,kka2_1:8_52,Kka2,kka2_1:8,P00552,1.07467,NO,52,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.271,-3.15,0.879,,0.22,E,B,0.75,0.8,5.447,,71.59,PAH,-2.38367,0.100394,0.00175694,1.07467 kka2_1:8_D52A,kka2_1:8_52,Kka2,kka2_1:8,P00552,1.07467,NO,52,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.271,-3.15,0.879,,0.22,E,B,0.75,0.8,5.447,,71.59,PAH,-2.38367,0.100394,0.00175694,1.07467 beta-lactamase_0_P255S,beta-lactamase_0_255,TEM-1,beta-lactamase_0,P62593,1.0747,NO,255,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.0500837,0.00499612,1.0747 beta-lactamase_39_F149Q,beta-lactamase_39_149,TEM-1,beta-lactamase_39,P62593,1.07473,NO,149,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.299,-4.204,2.905,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.0495842,0.00418462,1.07473 kka2_1:8_E111M,kka2_1:8_111,Kka2,kka2_1:8,P00552,1.07477,NO,111,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.28,-4.788,2.508,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.100394,0.00746789,1.07477 kka2_1:8_E111M,kka2_1:8_111,Kka2,kka2_1:8,P00552,1.07477,NO,111,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.28,-4.788,2.508,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.100394,0.00746789,1.07477 kka2_1:2_D180G,kka2_1:2_180,Kka2,kka2_1:2,P00552,1.07478,NO,180,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.416,-2.606,0.19,,1.03,S,a,0.75,1.5,1.27,,71.59,OAO,-2.02933,0.295029,0.00756412,1.07478 kka2_1:8_E169Y,kka2_1:8_169,Kka2,kka2_1:8,P00552,1.07478,NO,169,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.996,-4.385,2.389,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.100394,0.00730086,1.07478 kka2_1:8_E169Y,kka2_1:8_169,Kka2,kka2_1:8,P00552,1.07478,NO,169,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.996,-4.385,2.389,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.100394,0.00730086,1.07478 beta-lactamase_0_L100Y,beta-lactamase_0_100,TEM-1,beta-lactamase_0,P62593,1.07491,NO,100,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.218,-2.879,1.661,,0.343,,B,0.55,0.13,1.373,,63.29,AHH,-1.23467,0.0500837,0.00413885,1.07491 beta-lactamase_0_T147S,beta-lactamase_0_147,TEM-1,beta-lactamase_0,P62593,1.07491,NO,147,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.149,-2.487,1.338,,0.281,H,A,0.22,-0.68,3.487,,64.34,HPH,-1.456,0.0500837,0.00226017,1.07491 gb1_K239S,gb1_239,gb1,gb1,P06654,1.07492,NO,239,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-3.043,-1.667,-1.376,,,,,,,1.326,,45.54,HBO,-2.31467,0.177985,0.00207004,1.07492 beta-lactamase_39_M209F,beta-lactamase_39_209,TEM-1,beta-lactamase_39,P62593,1.07494,NO,209,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.442,-2.51,1.068,,,H,A,0.55,-0.97,1.167,,64.69,HHA,-1.52633,0.0495842,0.00625021,1.07494 PSD95pdz3_D357Q,PSD95pdz3_357,PSD95pdz3,PSD95pdz3,P31016,1.07495,NO,357,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.264,-3.356,2.092,5.22306,,,,,10.975,,,,OAP,-1.32367,0.0758425,0.000609015,1.07495 gb1_N234F,gb1_234,gb1,gb1,P06654,1.07502,NO,234,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-2.055,-4.132,2.077,,,,,,,1.235,,45.54,HPO,-2.05067,0.177985,0.00242189,1.07502 PSD95pdz3_S361H,PSD95pdz3_361,PSD95pdz3,PSD95pdz3,P31016,1.07502,NO,361,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.519,-4.137,2.618,4.8722,,,,,16.4533,,,,HPH,-1.47167,0.0758425,0.00055296,1.07502 kka2_1:8_A87C,kka2_1:8_87,Kka2,kka2_1:8,P00552,1.07503,NO,87,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.917,-5.153,3.236,,1.039,S,L,0.46,1.57,16.115,16.115,65.53,AHO,-1.822,0.100394,0.00791281,1.07503 kka2_1:8_A87C,kka2_1:8_87,Kka2,kka2_1:8,P00552,1.07503,NO,87,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.917,-5.153,3.236,,1.039,S,L,0.46,1.57,16.115,16.115,65.53,AHO,-1.822,0.100394,0.00791281,1.07503 kka2_1:2_G55L,kka2_1:2_55,Kka2,kka2_1:2,P00552,1.07507,NO,55,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.625,-2.999,1.374,,0.517,S,b,0.75,1.19,15.753,15.753,63.64,POH,-2.05967,0.295029,0.00667877,1.07507 beta-lactamase_0_T186I,beta-lactamase_0_186,TEM-1,beta-lactamase_0,P62593,1.0751,NO,186,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.522,-3.94,1.418,,0.396,H,A,0.22,-0.28,16.606,16.606,77.62,HPP,-1.77633,0.0500837,0.00485034,1.0751 beta-lactamase_39_S221Q,beta-lactamase_39_221,TEM-1,beta-lactamase_39,P62593,1.07511,NO,221,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.754,-3.871,2.117,,0.624,H,A,0.27,-0.2,2.69,,74.48,BPH,-1.59967,0.0495842,0.0046094,1.07511 kka2_1:8_C192V,kka2_1:8_192,Kka2,kka2_1:8,P00552,1.07511,NO,192,C,V,CV,Special,Hydrophobic,5.07,5.60847,0.538465,192,121,117,-4,108.5,140,31.5,-1.067,-3.41,2.343,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.100394,0.00485428,1.07511 kka2_1:8_C192V,kka2_1:8_192,Kka2,kka2_1:8,P00552,1.07511,NO,192,C,V,CV,Special,Hydrophobic,5.07,5.60847,0.538465,192,121,117,-4,108.5,140,31.5,-1.067,-3.41,2.343,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.100394,0.00485428,1.07511 beta-lactamase_0_N130S,beta-lactamase_0_130,TEM-1,beta-lactamase_0,P62593,1.07513,NO,130,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-0.798,-2.936,2.138,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.0500837,0.000683376,1.07513 beta-lactamase_0_D36M,beta-lactamase_0_36,TEM-1,beta-lactamase_0,P62593,1.07515,NO,36,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.732,-4.763,2.031,,0.555,H,A,0.75,1.17,13.689,13.689,77.62,AAP,-1.91167,0.0500837,0.00476483,1.07515 E1_Ubiquitin_Q41Y,E1_Ubiquitin_41,Uba1,E1_Ubiquitin,P0CG63,1.07515,NO,41,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-1.25,-3.755,2.505,,0.017,E,B,,-0.98,,,,PPB,-1.344,0.18783,0.00215097,1.07515 kka2_1:8_K138G,kka2_1:8_138,Kka2,kka2_1:8,P00552,1.07517,NO,138,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-2.5,-2.938,0.438,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.100394,0.00628542,1.07517 kka2_1:8_K138G,kka2_1:8_138,Kka2,kka2_1:8,P00552,1.07517,NO,138,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-2.5,-2.938,0.438,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.100394,0.00628542,1.07517 PSD95pdz3_R313K,PSD95pdz3_313,PSD95pdz3,PSD95pdz3,P31016,1.07517,NO,313,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.582,-2.464,0.882,6.63563,,,,,18.3955,,,,BBH,-1.59733,0.0758425,0.000840067,1.07517 beta-lactamase_0_T131M,beta-lactamase_0_131,TEM-1,beta-lactamase_0,P62593,1.07523,NO,131,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.328,-4.602,3.274,,,H,A,0.22,-0.69,3.306,,67.48,PPH,-1.00867,0.0500837,0.00345886,1.07523 gb1_E268F,gb1_268,gb1,gb1,P06654,1.07523,NO,268,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.918,-4.122,2.204,,,,,,,0.637,,37.28,OAH,-1.59733,0.177985,0.00423953,1.07523 PSD95pdz3_V365I,PSD95pdz3_365,PSD95pdz3,PSD95pdz3,P31016,1.07523,NO,365,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.592,-2.708,1.116,5.03791,,,,,18.9657,2.364,,81.35,OHA,-1.288,0.0758425,0.000649764,1.07523 beta-lactamase_39_T187Y,beta-lactamase_39_187,TEM-1,beta-lactamase_39,P62593,1.07524,NO,187,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.401,-4.271,2.87,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.0495842,0.00491782,1.07524 beta-lactamase_39_W208V,beta-lactamase_39_208,TEM-1,beta-lactamase_39,P62593,1.07526,NO,208,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-0.818,-3.754,2.936,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.0495842,0.00126609,1.07526 kka2_1:8_K138T,kka2_1:8_138,Kka2,kka2_1:8,P00552,1.07528,NO,138,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-2.5,-2.841,0.341,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.100394,0.00628542,1.07528 kka2_1:8_K138T,kka2_1:8_138,Kka2,kka2_1:8,P00552,1.07528,NO,138,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-2.5,-2.841,0.341,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.100394,0.00628542,1.07528 beta-lactamase_0_L38I,beta-lactamase_0_38,TEM-1,beta-lactamase_0,P62593,1.07531,NO,38,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.343,-2.44,1.097,,0.088,H,A,0.55,0.2,13.556,13.556,64.34,PHO,-1.78033,0.0500837,0.00373244,1.07531 kka2_1:8_E182H,kka2_1:8_182,Kka2,kka2_1:8,P00552,1.07534,NO,182,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.516,-2.568,1.052,,0.326,,B,1.52,0.75,2.568,,65.53,OAA,-1.806,0.100394,0.00641548,1.07534 kka2_1:8_E182H,kka2_1:8_182,Kka2,kka2_1:8,P00552,1.07534,NO,182,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.516,-2.568,1.052,,0.326,,B,1.52,0.75,2.568,,65.53,OAA,-1.806,0.100394,0.00641548,1.07534 beta-lactamase_0_A211R,beta-lactamase_0_211,TEM-1,beta-lactamase_0,P62593,1.07545,NO,211,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.896,-3.077,1.181,,0.369,T,A,0.46,-0.69,8.527,8.527,77.62,AHA,-1.94633,0.0500837,0.00648183,1.07545 kka2_1:8_E199I,kka2_1:8_199,Kka2,kka2_1:8,P00552,1.07545,NO,199,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.234,-3.975,1.741,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.100394,0.00854122,1.07545 kka2_1:8_E199I,kka2_1:8_199,Kka2,kka2_1:8,P00552,1.07545,NO,199,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.234,-3.975,1.741,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.100394,0.00854122,1.07545 PSD95pdz3_I316T,PSD95pdz3_316,PSD95pdz3,PSD95pdz3,P31016,1.07553,NO,316,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.63,-3.103,1.473,5.46166,,,,,19.005,,,,HHB,-1.62733,0.0758425,0.00112762,1.07553 kka2_1:8_A229W,kka2_1:8_229,Kka2,kka2_1:8,P00552,1.07555,NO,229,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.739,-5.507,3.768,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.100394,0.00942138,1.07555 kka2_1:8_A229W,kka2_1:8_229,Kka2,kka2_1:8,P00552,1.07555,NO,229,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.739,-5.507,3.768,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.100394,0.00942138,1.07555 beta-lactamase_0_Q86M,beta-lactamase_0_86,TEM-1,beta-lactamase_0,P62593,1.07556,NO,86,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.4,-3.46,1.06,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.0500837,0.00450027,1.07556 beta-lactamase_0_L188V,beta-lactamase_0_188,TEM-1,beta-lactamase_0,P62593,1.07562,NO,188,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.166,-3.017,1.851,,,H,A,0.55,-0.3,2.739,,60.14,PHB,-1.47033,0.0500837,0.00295687,1.07562 beta-lactamase_0_D231A,beta-lactamase_0_231,TEM-1,beta-lactamase_0,P62593,1.07563,NO,231,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.816,-3.3,2.484,,,E,B,0.75,-1.06,4.975,,65.38,HAB,-0.994,0.0500837,0.00107395,1.07563 beta-lactamase_0_V29T,beta-lactamase_0_29,TEM-1,beta-lactamase_0,P62593,1.07563,NO,29,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-2.856,-2.552,-0.304,,0.733,H,A,0.44,-0.78,21.916,21.916,93.01,HHB,-2.24733,0.0500837,0.00318969,1.07563 kka2_1:4_M197V,kka2_1:4_197,Kka2,kka2_1:4,P00552,1.07563,NO,197,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.707,-2.226,0.519,,0.121,E,B,0.55,-1.19,0.415,,65.53,HHH,-1.847,0.168804,0.00921295,1.07563 kka2_1:8_L60A,kka2_1:8_60,Kka2,kka2_1:8,P00552,1.07569,NO,60,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.997,-3.185,2.188,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.100394,0.00262176,1.07569 kka2_1:8_L60A,kka2_1:8_60,Kka2,kka2_1:8,P00552,1.07569,NO,60,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.997,-3.185,2.188,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.100394,0.00262176,1.07569 WW_domain_D194E,WW_domain_194,Yap65,WW_domain,P46937,1.0757,NO,194,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.536,-1.941,0.405,5.95614,,,,,,1.948,,74.4,HAP,-1.78933,0.153962,0.00483742,1.0757 beta-lactamase_0_F58R,beta-lactamase_0_58,TEM-1,beta-lactamase_0,P62593,1.07573,NO,58,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-2.914,-2.758,-0.156,,0.266,E,B,0.58,-0.07,24.637,24.637,77.62,PHB,-2.059,0.0500837,0.00523369,1.07573 kka2_1:4_D250A,kka2_1:4_250,Kka2,kka2_1:4,P00552,1.07587,NO,250,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.015,-3.315,2.3,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.168804,0.0177103,1.07587 kka2_1:2_A166V,kka2_1:2_166,Kka2,kka2_1:2,P00552,1.0759,NO,166,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.407,-3.015,0.608,,0.534,.,B,0.46,1.03,23.175,23.175,71.59,HHO,-2.421,0.295029,0.00799912,1.0759 PSD95pdz3_E352N,PSD95pdz3_352,PSD95pdz3,PSD95pdz3,P31016,1.07591,NO,352,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.587,-3.381,1.794,5.49659,,,,,24.2,2.525,,86.88,OAH,-1.314,0.0758425,0.000892231,1.07591 beta-lactamase_0_M180G,beta-lactamase_0_180,TEM-1,beta-lactamase_0,P62593,1.07594,NO,180,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-2.795,-3.389,0.594,,0.242,,B,0.55,-0.94,2.892,,77.62,PHO,-1.56433,0.0500837,0.00552048,1.07594 PSD95pdz3_I377Y,PSD95pdz3_377,PSD95pdz3,PSD95pdz3,P31016,1.07596,NO,377,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.873,-3.872,1.999,4.9532,,,,,19.185,2.364,,87.71,HHH,-1.49567,0.0758425,0.000795475,1.07596 beta-lactamase_156_A211M,beta-lactamase_156_211,TEM-1,beta-lactamase_156,P62593,1.07597,NO,211,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.896,-3.437,1.541,,0.369,T,A,0.46,-0.69,8.527,8.527,77.62,AHA,-1.94633,0.111618,0.00648183,1.07597 WW_domain_F189F,WW_domain_189,Yap65,WW_domain,P46937,1.07602,NO,189,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.632,-1.632,0,5.47284,,,,,,6.165,,56.94,HHH,-1.454,0.153962,0.00308453,1.07602 kka2_1:8_M148K,kka2_1:8_148,Kka2,kka2_1:8,P00552,1.07606,NO,148,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.847,-3.762,1.915,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.100394,0.00982664,1.07606 kka2_1:8_M148K,kka2_1:8_148,Kka2,kka2_1:8,P00552,1.07606,NO,148,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.847,-3.762,1.915,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.100394,0.00982664,1.07606 beta-lactamase_0_E145I,beta-lactamase_0_145,TEM-1,beta-lactamase_0,P62593,1.07607,NO,145,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.357,-4.11,1.753,,0.545,H,A,1.04,0.79,1.199,,77.62,BAH,-2.069,0.0500837,0.00553285,1.07607 WW_domain_E178A,WW_domain_178,Yap65,WW_domain,P46937,1.07609,NO,178,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.158,-2.855,1.697,5.22323,,,,,,,,,HAH,-1.299,0.153962,0.0016738,1.07609 kka2_1:8_R122Q,kka2_1:8_122,Kka2,kka2_1:8,P00552,1.07611,NO,122,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.175,-2.893,0.718,,0.487,H,A,1.2,0.26,22.675,22.675,71.59,BBH,-1.53833,0.100394,0.00736512,1.07611 kka2_1:8_R122Q,kka2_1:8_122,Kka2,kka2_1:8,P00552,1.07611,NO,122,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.175,-2.893,0.718,,0.487,H,A,1.2,0.26,22.675,22.675,71.59,BBH,-1.53833,0.100394,0.00736512,1.07611 PSD95pdz3_G333M,PSD95pdz3_333,PSD95pdz3,PSD95pdz3,P31016,1.07615,NO,333,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.008,-4.612,3.604,5.09445,,,,,48.755,,,,AOA,-1.22533,0.0758425,0.00092544,1.07615 beta-lactamase_0_R92V,beta-lactamase_0_92,TEM-1,beta-lactamase_0,P62593,1.07628,NO,92,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.718,-2.509,0.791,,0.479,E,B,1.2,1.36,2.331,,65.38,BBH,-1.50367,0.0500837,0.00429626,1.07628 beta-lactamase_0_S233H,beta-lactamase_0_233,TEM-1,beta-lactamase_0,P62593,1.07631,NO,233,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.886,-4.67,2.784,,0.016,E,B,0.27,-1.01,3.579,,77.62,BPO,-1.17267,0.0500837,0.00311415,1.07631 beta-lactamase_0_L188I,beta-lactamase_0_188,TEM-1,beta-lactamase_0,P62593,1.07639,NO,188,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.166,-2.584,1.418,,,H,A,0.55,-0.3,2.739,,60.14,PHB,-1.47033,0.0500837,0.00295687,1.07639 beta-lactamase_0_M153L,beta-lactamase_0_153,TEM-1,beta-lactamase_0,P62593,1.07639,NO,153,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-3.193,-1.8,-1.393,,0.14,T,A,0.55,-0.11,3.826,,77.62,PHO,-2.25767,0.0500837,0.00509109,1.07639 beta-lactamase_0_D271P,beta-lactamase_0_271,TEM-1,beta-lactamase_0,P62593,1.0764,NO,271,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.0500837,0.00752082,1.0764 kka2_1:8_A229Y,kka2_1:8_229,Kka2,kka2_1:8,P00552,1.07644,NO,229,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.739,-4.342,2.603,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.100394,0.00942138,1.07644 kka2_1:8_A229Y,kka2_1:8_229,Kka2,kka2_1:8,P00552,1.07644,NO,229,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.739,-4.342,2.603,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.100394,0.00942138,1.07644 beta-lactamase_39_W208S,beta-lactamase_39_208,TEM-1,beta-lactamase_39,P62593,1.07647,NO,208,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-0.818,-3.836,3.018,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.0495842,0.00126609,1.07647 kka2_1:2_S114N,kka2_1:2_114,Kka2,kka2_1:2,P00552,1.0765,NO,114,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.527,-3.164,0.637,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.295029,0.00705262,1.0765 PSD95pdz3_R318K,PSD95pdz3_318,PSD95pdz3,PSD95pdz3,P31016,1.07654,NO,318,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.582,-2.464,0.882,4.94876,,,,,17.5609,,,,BBO,-1.40567,0.0758425,0.00110471,1.07654 kka2_1:4_G10D,kka2_1:4_10,Kka2,kka2_1:4,P00552,1.07657,NO,10,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.921,-2.473,0.552,,,,,,,1.862,,71.59,HOP,-2.10733,0.168804,0.00289233,1.07657 kka2_1:2_R18I,kka2_1:2_18,Kka2,kka2_1:2,P00552,1.07658,NO,18,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.055,-3.256,1.201,,0.474,T,A,1.2,0.54,8.405,8.405,71.59,ABH,-1.821,0.295029,0.00724065,1.07658 beta-lactamase_0_E238A,beta-lactamase_0_238,TEM-1,beta-lactamase_0,P62593,1.07659,NO,238,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.0500837,0.00743256,1.07659 kka2_1:1_V242Q,kka2_1:1_242,Kka2,kka2_1:1,P00552,1.07662,NO,242,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-2.687,-2.985,0.298,,0.75,H,A,0.44,-0.37,4.987,,71.59,HHH,-2.16533,0.520039,0.0102575,1.07662 beta-lactamase_0_D113M,beta-lactamase_0_113,TEM-1,beta-lactamase_0,P62593,1.07664,NO,113,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.829,-4.826,2.997,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.0500837,0.00474112,1.07664 kka2_1:4_L81W,kka2_1:4_81,Kka2,kka2_1:4,P00552,1.0767,NO,81,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.427,-5.367,3.94,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.168804,0.00805839,1.0767 beta-lactamase_625_A211M,beta-lactamase_625_211,TEM-1,beta-lactamase_625,P62593,1.07672,NO,211,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.896,-3.437,1.541,,0.369,T,A,0.46,-0.69,2.061,,77.62,AHA,-1.94633,0.213352,0.00648183,1.07672 beta-lactamase_0_P255V,beta-lactamase_0_255,TEM-1,beta-lactamase_0,P62593,1.07673,NO,255,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.0500837,0.00499612,1.07673 PSD95pdz3_T321Y,PSD95pdz3_321,PSD95pdz3,PSD95pdz3,P31016,1.07674,NO,321,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.391,-3.844,2.453,5.19953,,,,,20.3371,,,,PPO,-1.306,0.0758425,0.00106992,1.07674 kka2_1:4_D250K,kka2_1:4_250,Kka2,kka2_1:4,P00552,1.07675,NO,250,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.015,-3.438,2.423,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.168804,0.0177103,1.07675 kka2_1:8_A9V,kka2_1:8_9,Kka2,kka2_1:8,P00552,1.07675,NO,9,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.079,-2.362,0.283,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.100394,0.00273264,1.07675 kka2_1:8_A9V,kka2_1:8_9,Kka2,kka2_1:8,P00552,1.07675,NO,9,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.079,-2.362,0.283,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.100394,0.00273264,1.07675 beta-lactamase_0_A215D,beta-lactamase_0_215,TEM-1,beta-lactamase_0,P62593,1.07676,NO,215,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.503,-3.621,2.118,,,,a,0.46,-0.93,0.494,,74.48,HHO,-1.42633,0.0500837,0.00544007,1.07676 beta-lactamase_0_H287N,beta-lactamase_0_287,TEM-1,beta-lactamase_0,P62593,1.0768,NO,287,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,,,,,,,,,,,,,BBH,-1.111,0.0500837,,1.0768 kka2_1:2_T28Q,kka2_1:2_28,Kka2,kka2_1:2,P00552,1.07682,NO,28,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.883,-4.073,2.19,,0.353,S,B,0.22,2.02,2.655,,63.64,PPH,-1.74467,0.295029,0.00743084,1.07682 PSD95pdz3_L353C,PSD95pdz3_353,PSD95pdz3,PSD95pdz3,P31016,1.07684,NO,353,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.347,-4.319,2.972,5.81136,,,,,17.3525,,,,AHB,-1.50533,0.0758425,0.000664742,1.07684 kka2_1:8_D154A,kka2_1:8_154,Kka2,kka2_1:8,P00552,1.07688,NO,154,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.876,-3.364,2.488,,0.457,,b,0.29,1.48,0.844,,52.65,HAP,-1.52467,0.100394,0.00292633,1.07688 kka2_1:8_D154A,kka2_1:8_154,Kka2,kka2_1:8,P00552,1.07688,NO,154,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.876,-3.364,2.488,,0.457,,b,0.29,1.48,0.844,,52.65,HAP,-1.52467,0.100394,0.00292633,1.07688 beta-lactamase_0_I244N,beta-lactamase_0_244,TEM-1,beta-lactamase_0,P62593,1.07691,NO,244,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.555,-4.114,2.559,,,E,B,0.48,-0.84,1.241,,77.62,OHH,-1.385,0.0500837,0.00605379,1.07691 kka2_1:1_D238Y,kka2_1:1_238,Kka2,kka2_1:1,P00552,1.07693,NO,238,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.83,-4.447,1.617,,0.604,H,A,0.75,-0.33,11.329,11.329,92.05,HAB,-2.633,0.520039,0.0113863,1.07693 kka2_1:8_D52L,kka2_1:8_52,Kka2,kka2_1:8,P00552,1.077,NO,52,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.271,-3.655,1.384,,0.22,E,B,0.75,0.8,5.447,,71.59,PAH,-2.38367,0.100394,0.00175694,1.077 kka2_1:8_D52L,kka2_1:8_52,Kka2,kka2_1:8,P00552,1.077,NO,52,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.271,-3.655,1.384,,0.22,E,B,0.75,0.8,5.447,,71.59,PAH,-2.38367,0.100394,0.00175694,1.077 kka2_1:8_T73N,kka2_1:8_73,Kka2,kka2_1:8,P00552,1.07701,NO,73,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.51,-3.876,1.366,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.100394,0.00628605,1.07701 kka2_1:8_T73N,kka2_1:8_73,Kka2,kka2_1:8,P00552,1.07701,NO,73,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.51,-3.876,1.366,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.100394,0.00628605,1.07701 kka2_1:4_G43W,kka2_1:4_43,Kka2,kka2_1:4,P00552,1.07707,NO,43,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.587,-5.439,3.852,,0.862,T,l,0.75,-0.67,2.247,,63.26,POB,-2.18533,0.168804,0.0071925,1.07707 beta-lactamase_0_L188C,beta-lactamase_0_188,TEM-1,beta-lactamase_0,P62593,1.07708,NO,188,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.166,-4.777,3.611,,,H,A,0.55,-0.3,2.739,,60.14,PHB,-1.47033,0.0500837,0.00295687,1.07708 beta-lactamase_0_L223D,beta-lactamase_0_223,TEM-1,beta-lactamase_0,P62593,1.07709,NO,223,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.055,-4.067,3.012,,0.27,,B,0.55,0.09,1.633,,74.48,HHO,-1.35033,0.0500837,0.00372793,1.07709 kka2_1:8_T125I,kka2_1:8_125,Kka2,kka2_1:8,P00552,1.07709,NO,125,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.622,-3.99,1.368,,0.791,T,A,0.22,0.33,2.675,,92.05,BPH,-1.56933,0.100394,0.00821755,1.07709 kka2_1:8_T125I,kka2_1:8_125,Kka2,kka2_1:8,P00552,1.07709,NO,125,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.622,-3.99,1.368,,0.791,T,A,0.22,0.33,2.675,,92.05,BPH,-1.56933,0.100394,0.00821755,1.07709 beta-lactamase_39_A183N,beta-lactamase_39_183,TEM-1,beta-lactamase_39,P62593,1.0771,NO,183,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.231,-2.504,1.273,,0.155,H,A,0.46,-0.91,1.237,,77.62,HHH,-1.53367,0.0495842,0.00296631,1.0771 PSD95pdz3_V315P,PSD95pdz3_315,PSD95pdz3,PSD95pdz3,P31016,1.07715,NO,315,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.625,-3.842,2.217,5.52024,,,,,18.4557,4.054,,81.35,HHH,-1.62767,0.0758425,0.00153536,1.07715 beta-lactamase_39_S201H,beta-lactamase_39_201,TEM-1,beta-lactamase_39,P62593,1.07716,NO,201,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.183,-4.595,3.412,,0.064,H,A,0.27,-0.07,3.54,,64.69,HPB,-1.451,0.0495842,0.00198815,1.07716 beta-lactamase_0_N168T,beta-lactamase_0_168,TEM-1,beta-lactamase_0,P62593,1.07718,NO,168,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-1.029,-2.214,1.185,,0.113,G,A,0.61,-0.4,0.881,,44.41,HPA,-1.13233,0.0500837,0.00288667,1.07718 beta-lactamase_39_P224N,beta-lactamase_39_224,TEM-1,beta-lactamase_39,P62593,1.07719,NO,224,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.893,-3.802,2.909,,0.383,,B,0.52,-0.3,3.169,,74.48,HOH,-1.26433,0.0495842,0.00189564,1.07719 PSD95pdz3_G364H,PSD95pdz3_364,PSD95pdz3,PSD95pdz3,P31016,1.07722,NO,364,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.008,-4.362,3.354,5.53299,,,,,21.28,,,,POH,-1.33667,0.0758425,0.00050942,1.07722 gb1_E245R,gb1_245,gb1,gb1,P06654,1.07733,NO,245,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.725,-2.768,0.043,,,,,,,0.712,,45.54,PAH,-1.84567,0.177985,0.00158611,1.07733 gb1_Q228F,gb1_228,gb1,gb1,P06654,1.07733,NO,228,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,,,,,,,,,,,,,OPH,-1.282,0.177985,0.00391043,1.07733 PSD95pdz3_E352M,PSD95pdz3_352,PSD95pdz3,PSD95pdz3,P31016,1.07735,NO,352,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.587,-4.386,2.799,5.49659,,,,,24.2,2.525,,86.88,OAH,-1.314,0.0758425,0.000892231,1.07735 beta-lactamase_0_T131L,beta-lactamase_0_131,TEM-1,beta-lactamase_0,P62593,1.07739,NO,131,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.328,-3.319,1.991,,,H,A,0.22,-0.69,3.306,,67.48,PPH,-1.00867,0.0500837,0.00345886,1.07739 WW_domain_V171M,WW_domain_171,Yap65,WW_domain,P46937,1.07739,NO,171,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.547,-2.601,1.054,,,,,,,3.459,,70.24,AHO,-1.265,0.153962,0.00184125,1.07739 PSD95pdz3_G333H,PSD95pdz3_333,PSD95pdz3,PSD95pdz3,P31016,1.0774,NO,333,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.008,-4.362,3.354,5.09445,,,,,48.755,,,,AOA,-1.22533,0.0758425,0.00092544,1.0774 beta-lactamase_0_I261M,beta-lactamase_0_261,TEM-1,beta-lactamase_0,P62593,1.07744,NO,261,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.0500837,0.0123091,1.07744 beta-lactamase_39_W208A,beta-lactamase_39_208,TEM-1,beta-lactamase_39,P62593,1.07746,NO,208,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-0.818,-3.528,2.71,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.0495842,0.00126609,1.07746 PSD95pdz3_I389C,PSD95pdz3_389,PSD95pdz3,PSD95pdz3,P31016,1.07747,NO,389,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.628,-4.414,2.786,5.15116,,,,,14.8038,1.498,,87.71,HHH,-1.52167,0.0758425,0.00148097,1.07747 beta-lactamase_0_I140Y,beta-lactamase_0_140,TEM-1,beta-lactamase_0,P62593,1.07749,NO,140,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.733,-3.996,2.263,,0.128,H,A,0.48,0.41,4.714,,73.08,PHO,-1.48733,0.0500837,0.00597777,1.07749 Pab1_N187A,Pab1_187,Pab1,Pab1,P04147,1.07752,NO,187,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-1.224,-3.173,1.949,,0.456,S,b,,1.87,,,,HPO,-1.272,0.175299,0.00083165,1.07752 beta-lactamase_0_L205Q,beta-lactamase_0_205,TEM-1,beta-lactamase_0,P62593,1.07753,NO,205,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.922,-4.179,3.257,,,H,A,0.55,-0.46,1.065,,42.31,PHH,-1.57767,0.0500837,0.00255802,1.07753 beta-lactamase_0_A278Y,beta-lactamase_0_278,TEM-1,beta-lactamase_0,P62593,1.07754,NO,278,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.348,,,,0.015,H,A,0.48,-0.85,4.624,,63.29,HHA,-1.41833,0.0500837,0.0310297,1.07754 WW_domain_R187T,WW_domain_187,Yap65,WW_domain,P46937,1.07756,NO,187,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.402,-3.261,1.859,5.05189,,,,,,3.431,,78.57,PBH,-1.362,0.153962,0.00171149,1.07756 beta-lactamase_0_T147A,beta-lactamase_0_147,TEM-1,beta-lactamase_0,P62593,1.07759,NO,147,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.149,-2.982,1.833,,0.281,H,A,0.22,-0.68,3.487,,64.34,HPH,-1.456,0.0500837,0.00226017,1.07759 beta-lactamase_0_E61L,beta-lactamase_0_61,TEM-1,beta-lactamase_0,P62593,1.07768,NO,61,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.115,-3.769,1.654,,0.775,T,a,1.04,1.29,34.763,34.763,77.62,OAA,-1.92567,0.0500837,0.00440955,1.07768 kka2_1:8_S104N,kka2_1:8_104,Kka2,kka2_1:8,P00552,1.07768,NO,104,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.436,-2.903,1.467,,0.536,T,A,0.27,-1.11,1.689,,63.64,HPP,-1.91433,0.100394,0.00555207,1.07768 kka2_1:8_S104N,kka2_1:8_104,Kka2,kka2_1:8,P00552,1.07768,NO,104,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.436,-2.903,1.467,,0.536,T,A,0.27,-1.11,1.689,,63.64,HPP,-1.91433,0.100394,0.00555207,1.07768 kka2_1:2_D156Q,kka2_1:2_156,Kka2,kka2_1:2,P00552,1.07774,NO,156,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.696,-3.891,2.195,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.295029,0.00926998,1.07774 beta-lactamase_0_E119I,beta-lactamase_0_119,TEM-1,beta-lactamase_0,P62593,1.07775,NO,119,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.412,-4.096,2.684,,0.358,H,A,1.04,0.51,3.396,,63.99,BAH,-1.623,0.0500837,0.00386966,1.07775 kka2_1:4_L103F,kka2_1:4_103,Kka2,kka2_1:4,P00552,1.07776,NO,103,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-2.362,-4.185,1.823,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.168804,0.00574792,1.07776 kka2_1:8_A129S,kka2_1:8_129,Kka2,kka2_1:8,P00552,1.07777,NO,129,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.656,-2.58,0.924,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.100394,0.00726862,1.07777 kka2_1:8_A129S,kka2_1:8_129,Kka2,kka2_1:8,P00552,1.07777,NO,129,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.656,-2.58,0.924,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.100394,0.00726862,1.07777 beta-lactamase_39_R92Y,beta-lactamase_39_92,TEM-1,beta-lactamase_39,P62593,1.07778,NO,92,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.718,-4.31,2.592,,0.479,E,B,1.2,1.36,0.389,,65.38,BBH,-1.50367,0.0495842,0.00429626,1.07778 kka2_1:8_V186I,kka2_1:8_186,Kka2,kka2_1:8,P00552,1.07779,NO,186,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.011,-2.092,1.081,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.100394,0.00409703,1.07779 kka2_1:8_V186I,kka2_1:8_186,Kka2,kka2_1:8,P00552,1.07779,NO,186,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.011,-2.092,1.081,,,E,B,0.44,-0.61,7.446,7.446,45.83,HHP,-1.10967,0.100394,0.00409703,1.07779 PSD95pdz3_T387F,PSD95pdz3_387,PSD95pdz3,PSD95pdz3,P31016,1.07779,NO,387,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.391,-3.749,2.358,5.20757,,,,,18.8043,,,,HPH,-1.49533,0.0758425,0.000167911,1.07779 kka2_1:4_A129S,kka2_1:4_129,Kka2,kka2_1:4,P00552,1.07782,NO,129,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.656,-2.58,0.924,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.168804,0.00726862,1.07782 kka2_1:8_P12A,kka2_1:8_12,Kka2,kka2_1:8,P00552,1.07784,NO,12,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.853,-2.153,1.3,,,.,B,0.52,1.25,2.41,,48.11,POH,-1.80767,0.100394,0.00500011,1.07784 kka2_1:8_P12A,kka2_1:8_12,Kka2,kka2_1:8,P00552,1.07784,NO,12,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-0.853,-2.153,1.3,,,.,B,0.52,1.25,2.41,,48.11,POH,-1.80767,0.100394,0.00500011,1.07784 kka2_1:2_R202E,kka2_1:2_202,Kka2,kka2_1:2,P00552,1.07788,NO,202,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.761,-2.596,0.835,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.295029,0.00696498,1.07788 kka2_1:4_V153L,kka2_1:4_153,Kka2,kka2_1:4,P00552,1.07793,NO,153,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.092,-2.743,1.651,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.168804,0.00501119,1.07793 kka2_1:8_E3V,kka2_1:8_3,Kka2,kka2_1:8,P00552,1.07793,NO,3,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.199,-3.503,1.304,,,,,,,7.22,,92.05,HAP,-2.11567,0.100394,0.00267607,1.07793 kka2_1:8_E3V,kka2_1:8_3,Kka2,kka2_1:8,P00552,1.07793,NO,3,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.199,-3.503,1.304,,,,,,,7.22,,92.05,HAP,-2.11567,0.100394,0.00267607,1.07793 beta-lactamase_0_Q37M,beta-lactamase_0_37,TEM-1,beta-lactamase_0,P62593,1.07797,NO,37,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.134,-4.645,2.511,,0.613,H,A,0.64,1.98,4.001,,73.08,APH,-2.06967,0.0500837,0.00425833,1.07797 WW_domain_P172S,WW_domain_172,Yap65,WW_domain,P46937,1.07797,NO,172,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.035,-3.163,2.128,,,,,,,,,,HOH,-1.233,0.153962,0.000991485,1.07797 kka2_1:2_H8A,kka2_1:2_8,Kka2,kka2_1:2,P00552,1.07798,NO,8,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-2.759,-1.998,-0.761,,,,,,,,,71.59,HBH,-2.25467,0.295029,0.00256422,1.07798 beta-lactamase_0_E210N,beta-lactamase_0_210,TEM-1,beta-lactamase_0,P62593,1.07801,NO,210,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.319,-3.904,1.585,,0.476,H,A,1.04,0.75,3.618,,77.62,HAH,-1.88567,0.0500837,0.00663582,1.07801 beta-lactamase_39_V106D,beta-lactamase_39_106,TEM-1,beta-lactamase_39,P62593,1.07804,NO,106,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.218,-4.056,2.838,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.0495842,0.00304168,1.07804 PSD95pdz3_G333S,PSD95pdz3_333,PSD95pdz3,PSD95pdz3,P31016,1.07805,NO,333,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.008,-2.842,1.834,5.09445,,,,,48.755,,,,AOA,-1.22533,0.0758425,0.00092544,1.07805 kka2_1:4_T51C,kka2_1:4_51,Kka2,kka2_1:4,P00552,1.07806,NO,51,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.199,-3.244,1.045,,0.05,E,B,0.82,-0.05,13.165,13.165,63.64,BPA,-1.76767,0.168804,0.00628861,1.07806 beta-lactamase_39_M209L,beta-lactamase_39_209,TEM-1,beta-lactamase_39,P62593,1.07814,NO,209,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.442,-1.689,0.247,,,H,A,0.55,-0.97,1.167,,64.69,HHA,-1.52633,0.0495842,0.00625021,1.07814 PSD95pdz3_G364M,PSD95pdz3_364,PSD95pdz3,PSD95pdz3,P31016,1.07814,NO,364,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.008,-4.612,3.604,5.53299,,,,,21.28,,,,POH,-1.33667,0.0758425,0.00050942,1.07814 beta-lactamase_0_I277P,beta-lactamase_0_277,TEM-1,beta-lactamase_0,P62593,1.07817,NO,277,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.0500837,0.0169305,1.07817 kka2_1:1_D5E,kka2_1:1_5,Kka2,kka2_1:1,P00552,1.07823,NO,5,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.306,-1.813,0.507,,,,,,,0.895,,71.59,PAO,-1.784,0.520039,0.00222864,1.07823 kka2_1:8_P76G,kka2_1:8_76,Kka2,kka2_1:8,P00552,1.07824,NO,76,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.449,-3.458,2.009,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.100394,0.00625685,1.07824 kka2_1:8_P76G,kka2_1:8_76,Kka2,kka2_1:8,P00552,1.07824,NO,76,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.449,-3.458,2.009,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.100394,0.00625685,1.07824 beta-lactamase_39_I171W,beta-lactamase_39_171,TEM-1,beta-lactamase_39,P62593,1.07825,NO,171,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-2.431,-5.376,2.945,,0.361,,B,0.48,0.53,16.954,16.954,77.62,HHO,-1.55533,0.0495842,0.00623355,1.07825 PSD95pdz3_E334H,PSD95pdz3_334,PSD95pdz3,PSD95pdz3,P31016,1.07826,NO,334,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.404,-3.912,2.508,5.60175,,,,,53.09,,,,OAO,-1.14,0.0758425,0.000912998,1.07826 kka2_1:8_A176W,kka2_1:8_176,Kka2,kka2_1:8,P00552,1.07828,NO,176,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.621,-5.554,3.933,,0.806,H,A,0.46,-0.03,18.904,18.904,65.53,BHB,-2.26667,0.100394,0.0083587,1.07828 kka2_1:8_A176W,kka2_1:8_176,Kka2,kka2_1:8,P00552,1.07828,NO,176,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.621,-5.554,3.933,,0.806,H,A,0.46,-0.03,18.904,18.904,65.53,BHB,-2.26667,0.100394,0.0083587,1.07828 kka2_1:8_K175A,kka2_1:8_175,Kka2,kka2_1:8,P00552,1.07828,NO,175,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-2.897,-2.718,-0.179,,0.579,H,A,2.34,0.51,15.316,15.316,71.59,HBH,-1.82333,0.100394,0.00693093,1.07828 kka2_1:8_K175A,kka2_1:8_175,Kka2,kka2_1:8,P00552,1.07828,NO,175,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-2.897,-2.718,-0.179,,0.579,H,A,2.34,0.51,15.316,15.316,71.59,HBH,-1.82333,0.100394,0.00693093,1.07828 kka2_1:8_L92M,kka2_1:8_92,Kka2,kka2_1:8,P00552,1.07831,NO,92,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.893,-2.898,2.005,,0.007,E,B,1.59,-0.19,1.719,,63.26,HHH,-0.962,0.100394,0.00307177,1.07831 kka2_1:8_L92M,kka2_1:8_92,Kka2,kka2_1:8,P00552,1.07831,NO,92,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.893,-2.898,2.005,,0.007,E,B,1.59,-0.19,1.719,,63.26,HHH,-0.962,0.100394,0.00307177,1.07831 beta-lactamase_0_R92W,beta-lactamase_0_92,TEM-1,beta-lactamase_0,P62593,1.07834,NO,92,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.718,-5.477,3.759,,0.479,E,B,1.2,1.36,2.331,,65.38,BBH,-1.50367,0.0500837,0.00429626,1.07834 beta-lactamase_0_V157K,beta-lactamase_0_157,TEM-1,beta-lactamase_0,P62593,1.07836,NO,157,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.751,-2.698,0.947,,0.308,S,a,0.44,-0.75,3.106,,69.58,BHP,-2.00767,0.0500837,0.00506849,1.07836 kka2_1:8_A9F,kka2_1:8_9,Kka2,kka2_1:8,P00552,1.07836,NO,9,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.079,-3.934,1.855,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.100394,0.00273264,1.07836 kka2_1:8_A9F,kka2_1:8_9,Kka2,kka2_1:8,P00552,1.07836,NO,9,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.079,-3.934,1.855,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.100394,0.00273264,1.07836 kka2_1:8_E230D,kka2_1:8_230,Kka2,kka2_1:8,P00552,1.07836,NO,230,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.672,-2.56,-0.112,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.100394,0.00920051,1.07836 kka2_1:8_E230D,kka2_1:8_230,Kka2,kka2_1:8,P00552,1.07836,NO,230,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.672,-2.56,-0.112,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.100394,0.00920051,1.07836 kka2_1:8_M178S,kka2_1:8_178,Kka2,kka2_1:8,P00552,1.07841,NO,178,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-3.206,-2.817,-0.389,,0.554,,b,1.59,0.68,13.268,13.268,71.59,BHO,-2.154,0.100394,0.00717253,1.07841 kka2_1:8_M178S,kka2_1:8_178,Kka2,kka2_1:8,P00552,1.07841,NO,178,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-3.206,-2.817,-0.389,,0.554,,b,1.59,0.68,13.268,13.268,71.59,BHO,-2.154,0.100394,0.00717253,1.07841 gb1_T277Y,gb1_277,gb1,gb1,P06654,1.07842,NO,277,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.771,-4.1,2.329,,,,,,,0.824,,35.71,BPH,-1.54833,0.177985,0.00348258,1.07842 kka2_1:2_A229K,kka2_1:2_229,Kka2,kka2_1:2,P00552,1.0785,NO,229,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.739,-3.497,1.758,,0.32,H,A,0.46,-0.7,6.549,,63.64,HHA,-1.851,0.295029,0.00942138,1.0785 PSD95pdz3_H317V,PSD95pdz3_317,PSD95pdz3,PSD95pdz3,P31016,1.07856,NO,317,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-1.627,-3.435,1.808,6.19713,,,,,25.885,,,,HBB,-1.613,0.0758425,0.00111619,1.07856 kka2_1:8_G43P,kka2_1:8_43,Kka2,kka2_1:8,P00552,1.07859,NO,43,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.587,-4.038,2.451,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.100394,0.0071925,1.07859 kka2_1:8_G43P,kka2_1:8_43,Kka2,kka2_1:8,P00552,1.07859,NO,43,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.587,-4.038,2.451,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.100394,0.0071925,1.07859 beta-lactamase_0_G253M,beta-lactamase_0_253,TEM-1,beta-lactamase_0,P62593,1.07861,NO,253,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.0500837,0.00786358,1.07861 kka2_1:4_T73F,kka2_1:4_73,Kka2,kka2_1:4,P00552,1.07862,NO,73,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.51,-4.242,1.732,,0.309,H,A,0.22,0.35,1.53,,56.06,PPO,-2.02333,0.168804,0.00628605,1.07862 kka2_1:2_E160I,kka2_1:2_160,Kka2,kka2_1:2,P00552,1.07868,NO,160,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.683,-4.13,2.447,,0.989,G,A,1.04,2.28,3.948,,71.59,AAA,-1.36133,0.295029,0.00935762,1.07868 kka2_1:8_L81R,kka2_1:8_81,Kka2,kka2_1:8,P00552,1.07875,NO,81,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.427,-4.145,2.718,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.100394,0.00805839,1.07875 kka2_1:8_L81R,kka2_1:8_81,Kka2,kka2_1:8,P00552,1.07875,NO,81,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.427,-4.145,2.718,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.100394,0.00805839,1.07875 kka2_1:2_E230T,kka2_1:2_230,Kka2,kka2_1:2,P00552,1.07882,NO,230,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.672,-3.072,0.4,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.295029,0.00920051,1.07882 PSD95pdz3_T321S,PSD95pdz3_321,PSD95pdz3,PSD95pdz3,P31016,1.07882,NO,321,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.391,-2.617,1.226,5.19953,,,,,20.3371,,,,PPO,-1.306,0.0758425,0.00106992,1.07882 gb1_A250V,gb1_250,gb1,gb1,P06654,1.07891,NO,250,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.713,-3.243,1.53,,,,,,,3.465,,45.54,HHP,-1.74867,0.177985,0.00332003,1.07891 gb1_Q258N,gb1_258,gb1,gb1,P06654,1.07891,NO,258,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.095,-1.945,-0.15,,,,,,,0.86,,37.28,BPH,-1.88333,0.177985,0.00437595,1.07891 kka2_1:2_P45G,kka2_1:2_45,Kka2,kka2_1:2,P00552,1.07892,NO,45,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.774,-2.532,0.758,,0.669,,B,0.52,-0.76,4.882,,71.59,BOH,-2.152,0.295029,0.00590481,1.07892 kka2_1:4_T73L,kka2_1:4_73,Kka2,kka2_1:4,P00552,1.07898,NO,73,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.51,-2.574,0.064,,0.309,H,A,0.22,0.35,1.53,,56.06,PPO,-2.02333,0.168804,0.00628605,1.07898 beta-lactamase_0_Q37P,beta-lactamase_0_37,TEM-1,beta-lactamase_0,P62593,1.07905,NO,37,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.134,-3.965,1.831,,0.613,H,A,0.64,1.98,4.001,,73.08,APH,-2.06967,0.0500837,0.00425833,1.07905 kka2_1:8_P45M,kka2_1:8_45,Kka2,kka2_1:8,P00552,1.0791,NO,45,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.774,-4.81,3.036,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.100394,0.00590481,1.0791 kka2_1:8_P45M,kka2_1:8_45,Kka2,kka2_1:8,P00552,1.0791,NO,45,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.774,-4.81,3.036,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.100394,0.00590481,1.0791 kka2_1:8_G245N,kka2_1:8_245,Kka2,kka2_1:8,P00552,1.07912,NO,245,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.812,-2.694,1.882,,0.655,T,g,0.75,0.03,1.148,,65.53,HOH,-1.19833,0.100394,0.00683899,1.07912 kka2_1:8_G245N,kka2_1:8_245,Kka2,kka2_1:8,P00552,1.07912,NO,245,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.812,-2.694,1.882,,0.655,T,g,0.75,0.03,1.148,,65.53,HOH,-1.19833,0.100394,0.00683899,1.07912 kka2_1:4_A41S,kka2_1:4_41,Kka2,kka2_1:4,P00552,1.07913,NO,41,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.879,-2.842,0.963,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.168804,0.00543332,1.07913 kka2_1:8_A9Y,kka2_1:8_9,Kka2,kka2_1:8,P00552,1.07917,NO,9,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.079,-4.09,2.011,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.100394,0.00273264,1.07917 kka2_1:8_A9Y,kka2_1:8_9,Kka2,kka2_1:8,P00552,1.07917,NO,9,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.079,-4.09,2.011,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.100394,0.00273264,1.07917 beta-lactamase_0_E238L,beta-lactamase_0_238,TEM-1,beta-lactamase_0,P62593,1.07923,NO,238,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.0500837,0.00743256,1.07923 kka2_1:4_A229K,kka2_1:4_229,Kka2,kka2_1:4,P00552,1.07926,NO,229,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.739,-3.497,1.758,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.168804,0.00942138,1.07926 kka2_1:8_A25C,kka2_1:8_25,Kka2,kka2_1:8,P00552,1.07938,NO,25,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.496,-5.199,2.703,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.100394,0.00595636,1.07938 kka2_1:8_A25C,kka2_1:8_25,Kka2,kka2_1:8,P00552,1.07938,NO,25,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.496,-5.199,2.703,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.100394,0.00595636,1.07938 kka2_1:8_A119C,kka2_1:8_119,Kka2,kka2_1:8,P00552,1.0794,NO,119,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.073,-4.641,3.568,,0.019,H,A,0.46,-0.57,1.511,,71.59,AHH,-2.34,0.100394,0.00441074,1.0794 kka2_1:8_A119C,kka2_1:8_119,Kka2,kka2_1:8,P00552,1.0794,NO,119,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.073,-4.641,3.568,,0.019,H,A,0.46,-0.57,1.511,,71.59,AHH,-2.34,0.100394,0.00441074,1.0794 kka2_1:8_L7D,kka2_1:8_7,Kka2,kka2_1:8,P00552,1.0794,NO,7,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.926,-2.297,0.371,,,,,,,,,71.59,OHB,-2.12333,0.100394,0.00269456,1.0794 kka2_1:8_L7D,kka2_1:8_7,Kka2,kka2_1:8,P00552,1.0794,NO,7,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.926,-2.297,0.371,,,,,,,,,71.59,OHB,-2.12333,0.100394,0.00269456,1.0794 beta-lactamase_0_L120V,beta-lactamase_0_120,TEM-1,beta-lactamase_0,P62593,1.07945,NO,120,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.044,-3.031,1.987,,,H,A,0.55,-1.13,1.2,,64.69,AHO,-1.13633,0.0500837,0.00143563,1.07945 PSD95pdz3_I389L,PSD95pdz3_389,PSD95pdz3,PSD95pdz3,P31016,1.07945,NO,389,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.628,-2.319,0.691,5.15116,,,,,14.8038,1.498,,87.71,HHH,-1.52167,0.0758425,0.00148097,1.07945 beta-lactamase_0_S241G,beta-lactamase_0_241,TEM-1,beta-lactamase_0,P62593,1.0795,NO,241,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.0500837,0.00452736,1.0795 PSD95pdz3_S320G,PSD95pdz3_320,PSD95pdz3,PSD95pdz3,P31016,1.0795,NO,320,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.519,-2.59,1.071,5.81757,,,,,21.4517,,,,OPP,-1.306,0.0758425,0.00108158,1.0795 WW_domain_I193N,WW_domain_193,Yap65,WW_domain,P46937,1.07954,NO,193,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.993,-2.415,0.422,6.15906,,,,,,1.833,,83.33,BHA,-1.756,0.153962,0.00587613,1.07954 kka2_1:4_A56T,kka2_1:4_56,Kka2,kka2_1:4,P00552,1.07957,NO,56,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.083,-2.626,0.543,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.168804,0.00717715,1.07957 kka2_1:4_A35V,kka2_1:4_35,Kka2,kka2_1:4,P00552,1.07959,NO,35,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.127,-3.696,1.569,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.168804,0.00630016,1.07959 gb1_A246K,gb1_246,gb1,gb1,P06654,1.0796,NO,246,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.175,-3.192,2.017,,,,,,,,,,AHH,-1.87033,0.177985,0.00190625,1.0796 gb1_D248W,gb1_248,gb1,gb1,P06654,1.0796,NO,248,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.569,-5.24,3.671,,,,,,,0.344,,11.83,HAH,-1.673,0.177985,0.001865,1.0796 beta-lactamase_0_E195K,beta-lactamase_0_195,TEM-1,beta-lactamase_0,P62593,1.07962,NO,195,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.186,-2.529,0.343,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.0500837,0.00496565,1.07962 beta-lactamase_0_I245C,beta-lactamase_0_245,TEM-1,beta-lactamase_0,P62593,1.07962,NO,245,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.0500837,0.00391032,1.07962 beta-lactamase_0_L223N,beta-lactamase_0_223,TEM-1,beta-lactamase_0,P62593,1.07972,NO,223,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.055,-4.1,3.045,,0.27,,B,0.55,0.09,1.633,,74.48,HHO,-1.35033,0.0500837,0.00372793,1.07972 kka2_1:4_T146D,kka2_1:4_146,Kka2,kka2_1:4,P00552,1.07973,NO,146,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.978,-3.05,0.072,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.168804,0.00606474,1.07973 kka2_1:8_G74I,kka2_1:8_74,Kka2,kka2_1:8,P00552,1.07978,NO,74,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.18,-4.265,3.085,,0.621,T,l,0.29,0.2,2.014,,64.39,POH,-1.91667,0.100394,0.00587035,1.07978 kka2_1:8_G74I,kka2_1:8_74,Kka2,kka2_1:8,P00552,1.07978,NO,74,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.18,-4.265,3.085,,0.621,T,l,0.29,0.2,2.014,,64.39,POH,-1.91667,0.100394,0.00587035,1.07978 kka2_1:4_E142L,kka2_1:4_142,Kka2,kka2_1:4,P00552,1.07979,NO,142,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.221,-3.056,0.835,,0.471,H,A,1.52,0.85,3.693,,65.53,HAB,-2.08033,0.168804,0.00748883,1.07979 gb1_E268K,gb1_268,gb1,gb1,P06654,1.0798,NO,268,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.918,-2.23,0.312,,,,,,,0.637,,37.28,OAH,-1.59733,0.177985,0.00423953,1.0798 kka2_1:4_S54W,kka2_1:4_54,Kka2,kka2_1:4,P00552,1.0798,NO,54,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.471,-5.559,3.088,,0.408,S,b,0.27,1.01,17.332,17.332,71.59,HPO,-2.259,0.168804,0.00782867,1.0798 kka2_1:4_E111M,kka2_1:4_111,Kka2,kka2_1:4,P00552,1.07981,NO,111,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.28,-4.788,2.508,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.168804,0.00746789,1.07981 kka2_1:4_A129G,kka2_1:4_129,Kka2,kka2_1:4,P00552,1.07982,NO,129,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.656,-2.673,1.017,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.168804,0.00726862,1.07982 beta-lactamase_0_H24C,beta-lactamase_0_24,TEM-1,beta-lactamase_0,P62593,1.07984,NO,24,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-2.481,-4.897,2.416,,,,,,,2.708,,93.01,OBO,-2.0035,0.0500837,0.00238894,1.07984 kka2_1:4_G201R,kka2_1:4_201,Kka2,kka2_1:4,P00552,1.07984,NO,201,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.56,-2.756,1.196,,0.149,T,l,0.29,-0.57,0.284,,52.65,POB,-1.92233,0.168804,0.00820117,1.07984 beta-lactamase_0_T264F,beta-lactamase_0_264,TEM-1,beta-lactamase_0,P62593,1.07987,NO,264,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.0500837,0.0119399,1.07987 kka2_1:4_R145W,kka2_1:4_145,Kka2,kka2_1:4,P00552,1.07989,NO,145,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.804,-3.243,1.439,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.168804,0.00846663,1.07989 kka2_1:8_A79F,kka2_1:8_79,Kka2,kka2_1:8,P00552,1.07989,NO,79,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.368,-4.451,2.083,,0.563,.,B,0.46,-0.43,,,71.59,HHH,-1.752,0.100394,0.00664821,1.07989 kka2_1:8_A79F,kka2_1:8_79,Kka2,kka2_1:8,P00552,1.07989,NO,79,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.368,-4.451,2.083,,0.563,.,B,0.46,-0.43,,,71.59,HHH,-1.752,0.100394,0.00664821,1.07989 beta-lactamase_0_A84H,beta-lactamase_0_84,TEM-1,beta-lactamase_0,P62593,1.07994,NO,84,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.651,-3.344,1.693,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.0500837,0.00503822,1.07994 kka2_1:2_A137C,kka2_1:2_137,Kka2,kka2_1:2,P00552,1.07998,NO,137,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.156,-4.817,2.661,,0.029,H,A,0.46,0.34,1.323,,63.26,PHB,-2.559,0.295029,0.00515054,1.07998 kka2_1:4_P76D,kka2_1:4_76,Kka2,kka2_1:4,P00552,1.08001,NO,76,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.449,-2.541,1.092,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.168804,0.00625685,1.08001 kka2_1:8_V242L,kka2_1:8_242,Kka2,kka2_1:8,P00552,1.08002,NO,242,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-2.687,-3.55,0.863,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.100394,0.0102575,1.08002 kka2_1:8_V242L,kka2_1:8_242,Kka2,kka2_1:8,P00552,1.08002,NO,242,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-2.687,-3.55,0.863,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.100394,0.0102575,1.08002 kka2_1:8_V49L,kka2_1:8_49,Kka2,kka2_1:8,P00552,1.08004,NO,49,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.614,-1.314,-0.3,,,E,B,1.48,-0.77,1.31,,64.39,HHB,-1.3,0.100394,0.00615685,1.08004 kka2_1:8_V49L,kka2_1:8_49,Kka2,kka2_1:8,P00552,1.08004,NO,49,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.614,-1.314,-0.3,,,E,B,1.48,-0.77,1.31,,64.39,HHB,-1.3,0.100394,0.00615685,1.08004 beta-lactamase_0_E238T,beta-lactamase_0_238,TEM-1,beta-lactamase_0,P62593,1.08007,NO,238,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.0500837,0.00743256,1.08007 kka2_1:4_S40G,kka2_1:4_40,Kka2,kka2_1:4,P00552,1.08007,NO,40,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.645,-3.566,0.921,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.168804,0.00693477,1.08007 beta-lactamase_0_V106P,beta-lactamase_0_106,TEM-1,beta-lactamase_0,P62593,1.08017,NO,106,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.218,-4.094,2.876,,0.258,T,A,0.44,0.24,0.952,,72.73,OHP,-1.04933,0.0500837,0.00304168,1.08017 kka2_1:8_A14M,kka2_1:8_14,Kka2,kka2_1:8,P00552,1.0802,NO,14,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.837,-4.736,2.899,,0.728,G,A,0.46,0.7,,,71.59,HHH,-1.82567,0.100394,0.00706614,1.0802 kka2_1:8_A14M,kka2_1:8_14,Kka2,kka2_1:8,P00552,1.0802,NO,14,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.837,-4.736,2.899,,0.728,G,A,0.46,0.7,,,71.59,HHH,-1.82567,0.100394,0.00706614,1.0802 kka2_1:8_A229C,kka2_1:8_229,Kka2,kka2_1:8,P00552,1.0802,NO,229,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.739,-5.054,3.315,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.100394,0.00942138,1.0802 kka2_1:8_A229C,kka2_1:8_229,Kka2,kka2_1:8,P00552,1.0802,NO,229,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.739,-5.054,3.315,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.100394,0.00942138,1.0802 beta-lactamase_0_L100V,beta-lactamase_0_100,TEM-1,beta-lactamase_0,P62593,1.08021,NO,100,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.218,-2.049,0.831,,0.343,,B,0.55,0.13,1.373,,63.29,AHH,-1.23467,0.0500837,0.00413885,1.08021 beta-lactamase_39_F228Q,beta-lactamase_39_228,TEM-1,beta-lactamase_39,P62593,1.08024,NO,228,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-2.342,-2.674,0.332,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.0495842,0.0046669,1.08024 beta-lactamase_0_A34N,beta-lactamase_0_34,TEM-1,beta-lactamase_0,P62593,1.08027,NO,34,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.059,-3.965,1.906,,,H,A,0.46,-0.54,3.998,,73.78,AHA,-1.74967,0.0500837,0.00407913,1.08027 kka2_1:8_E142N,kka2_1:8_142,Kka2,kka2_1:8,P00552,1.08031,NO,142,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.221,-3.851,1.63,,0.471,H,A,1.04,0.85,2.655,,65.53,HAB,-2.08033,0.100394,0.00748883,1.08031 kka2_1:8_E142N,kka2_1:8_142,Kka2,kka2_1:8,P00552,1.08031,NO,142,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.221,-3.851,1.63,,0.471,H,A,1.04,0.85,2.655,,65.53,HAB,-2.08033,0.100394,0.00748883,1.08031 beta-lactamase_0_E145A,beta-lactamase_0_145,TEM-1,beta-lactamase_0,P62593,1.08034,NO,145,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.357,-1.901,-0.456,,0.545,H,A,1.04,0.79,1.199,,77.62,BAH,-2.069,0.0500837,0.00553285,1.08034 kka2_1:8_A110F,kka2_1:8_110,Kka2,kka2_1:8,P00552,1.08034,NO,110,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.064,-3.489,1.425,,0.175,H,A,1.04,-1.19,11.413,11.413,71.59,OHA,-1.91867,0.100394,0.00759851,1.08034 kka2_1:8_A110F,kka2_1:8_110,Kka2,kka2_1:8,P00552,1.08034,NO,110,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.064,-3.489,1.425,,0.175,H,A,1.04,-1.19,11.413,11.413,71.59,OHA,-1.91867,0.100394,0.00759851,1.08034 kka2_1:8_A137V,kka2_1:8_137,Kka2,kka2_1:8,P00552,1.08034,NO,137,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.156,-2.289,0.133,,0.029,H,A,1.04,0.34,2.886,,63.26,PHB,-2.559,0.100394,0.00515054,1.08034 kka2_1:8_A137V,kka2_1:8_137,Kka2,kka2_1:8,P00552,1.08034,NO,137,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.156,-2.289,0.133,,0.029,H,A,1.04,0.34,2.886,,63.26,PHB,-2.559,0.100394,0.00515054,1.08034 kka2_1:4_I115V,kka2_1:4_115,Kka2,kka2_1:4,P00552,1.08035,NO,115,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.606,-2.022,0.416,,0.105,H,A,1.52,-1.18,9.996,9.996,65.53,PHH,-2.205,0.168804,0.00836567,1.08035 kka2_1:8_G88E,kka2_1:8_88,Kka2,kka2_1:8,P00552,1.08037,NO,88,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.689,-2.331,0.642,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.100394,0.00685559,1.08037 kka2_1:8_G88E,kka2_1:8_88,Kka2,kka2_1:8,P00552,1.08037,NO,88,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.689,-2.331,0.642,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.100394,0.00685559,1.08037 beta-lactamase_0_Q88D,beta-lactamase_0_88,TEM-1,beta-lactamase_0,P62593,1.08038,NO,88,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.086,-2.035,-0.051,,0.807,,B,0.64,2.03,0.4,,77.62,APH,-1.53433,0.0500837,0.00504167,1.08038 kka2_1:4_E17G,kka2_1:4_17,Kka2,kka2_1:4,P00552,1.0804,NO,17,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.154,-2.597,0.443,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.168804,0.00688738,1.0804 kka2_1:8_L165Q,kka2_1:8_165,Kka2,kka2_1:8,P00552,1.0804,NO,165,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-2.453,-2.33,-0.123,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.100394,0.00801161,1.0804 kka2_1:8_L165Q,kka2_1:8_165,Kka2,kka2_1:8,P00552,1.0804,NO,165,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-2.453,-2.33,-0.123,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.100394,0.00801161,1.0804 kka2_1:8_G21T,kka2_1:8_21,Kka2,kka2_1:8,P00552,1.08042,NO,21,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.368,-3.639,2.271,,0.586,T,l,0.29,-0.75,4.889,,71.59,HOH,-2.10167,0.100394,0.00709648,1.08042 kka2_1:8_G21T,kka2_1:8_21,Kka2,kka2_1:8,P00552,1.08042,NO,21,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.368,-3.639,2.271,,0.586,T,l,0.29,-0.75,4.889,,71.59,HOH,-2.10167,0.100394,0.00709648,1.08042 beta-lactamase_0_I206H,beta-lactamase_0_206,TEM-1,beta-lactamase_0,P62593,1.08045,NO,206,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-2.429,-4.842,2.413,,0.173,H,A,0.48,-0.34,3.411,,77.62,HHA,-1.805,0.0500837,0.00528934,1.08045 PSD95pdz3_G335E,PSD95pdz3_335,PSD95pdz3,PSD95pdz3,P31016,1.08045,NO,335,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.008,-3.347,2.339,4.76223,,,,,22.4225,,,,AOH,-1.34733,0.0758425,0.000900493,1.08045 kka2_1:4_R18W,kka2_1:4_18,Kka2,kka2_1:4,P00552,1.08046,NO,18,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.055,-5.448,3.393,,0.474,T,A,1.2,0.54,8.405,8.405,71.59,ABH,-1.821,0.168804,0.00724065,1.08046 kka2_1:8_D238G,kka2_1:8_238,Kka2,kka2_1:8,P00552,1.08046,NO,238,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.83,-2.923,0.093,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.100394,0.0113863,1.08046 kka2_1:8_D238G,kka2_1:8_238,Kka2,kka2_1:8,P00552,1.08046,NO,238,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.83,-2.923,0.093,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.100394,0.0113863,1.08046 gb1_T251Q,gb1_251,gb1,gb1,P06654,1.08048,NO,251,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.794,-3.494,1.7,,,,,,,3.514,3.514,37.28,HPH,-1.56067,0.177985,0.00232932,1.08048 kka2_1:1_A172E,kka2_1:1_172,Kka2,kka2_1:1,P00552,1.08049,NO,172,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.757,-2.527,0.77,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.520039,0.0079265,1.08049 beta-lactamase_0_R189A,beta-lactamase_0_189,TEM-1,beta-lactamase_0,P62593,1.08058,NO,189,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.844,-2.739,0.895,,0.278,H,A,1.2,1.01,12.11,12.11,72.73,HBB,-1.668,0.0500837,0.0050699,1.08058 kka2_1:8_E161D,kka2_1:8_161,Kka2,kka2_1:8,P00552,1.08059,NO,161,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.581,-2.26,0.679,,0.829,G,A,1.04,2.24,11.923,11.923,92.05,AAB,-1.861,0.100394,0.00760103,1.08059 kka2_1:8_E161D,kka2_1:8_161,Kka2,kka2_1:8,P00552,1.08059,NO,161,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.581,-2.26,0.679,,0.829,G,A,1.04,2.24,11.923,11.923,92.05,AAB,-1.861,0.100394,0.00760103,1.08059 beta-lactamase_0_M270G,beta-lactamase_0_270,TEM-1,beta-lactamase_0,P62593,1.08061,NO,270,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.0500837,0.00767762,1.08061 kka2_1:4_A191Y,kka2_1:4_191,Kka2,kka2_1:4,P00552,1.08062,NO,191,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.831,-4.254,3.423,,,.,b,0.46,-0.94,2.046,,50,AHO,-0.868667,0.168804,0.00338807,1.08062 kka2_1:4_L259C,kka2_1:4_259,Kka2,kka2_1:4,P00552,1.08067,NO,259,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.088,-4.727,3.639,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.168804,0.0206964,1.08067 beta-lactamase_0_G234D,beta-lactamase_0_234,TEM-1,beta-lactamase_0,P62593,1.08069,NO,234,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.62,-3.469,2.849,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.0500837,0.000889577,1.08069 kka2_1:8_I29H,kka2_1:8_29,Kka2,kka2_1:8,P00552,1.0807,NO,29,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.692,-4.894,3.202,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.100394,0.00619521,1.0807 kka2_1:8_I29H,kka2_1:8_29,Kka2,kka2_1:8,P00552,1.0807,NO,29,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.692,-4.894,3.202,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.100394,0.00619521,1.0807 beta-lactamase_0_I280H,beta-lactamase_0_280,TEM-1,beta-lactamase_0,P62593,1.08081,NO,280,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.0500837,0.0530888,1.08081 PSD95pdz3_E352Q,PSD95pdz3_352,PSD95pdz3,PSD95pdz3,P31016,1.08081,NO,352,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.587,-3.22,1.633,5.49659,,,,,24.2,2.525,,86.88,OAH,-1.314,0.0758425,0.000892231,1.08081 kka2_1:8_I141Y,kka2_1:8_141,Kka2,kka2_1:8,P00552,1.08083,NO,141,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.495,-4.112,2.617,,0.068,H,A,1.52,-0.01,2.144,,92.05,BHA,-1.689,0.100394,0.00744745,1.08083 kka2_1:8_I141Y,kka2_1:8_141,Kka2,kka2_1:8,P00552,1.08083,NO,141,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.495,-4.112,2.617,,0.068,H,A,1.52,-0.01,2.144,,92.05,BHA,-1.689,0.100394,0.00744745,1.08083 kka2_1:2_I115V,kka2_1:2_115,Kka2,kka2_1:2,P00552,1.08086,NO,115,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.606,-2.022,0.416,,0.105,H,A,0.48,-1.18,0.878,,65.53,PHH,-2.205,0.295029,0.00836567,1.08086 kka2_1:8_A41L,kka2_1:8_41,Kka2,kka2_1:8,P00552,1.08087,NO,41,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.879,-3.033,1.154,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.100394,0.00543332,1.08087 kka2_1:8_A41L,kka2_1:8_41,Kka2,kka2_1:8,P00552,1.08087,NO,41,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.879,-3.033,1.154,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.100394,0.00543332,1.08087 beta-lactamase_0_L120A,beta-lactamase_0_120,TEM-1,beta-lactamase_0,P62593,1.08088,NO,120,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.044,-3.203,2.159,,,H,A,0.55,-1.13,1.2,,64.69,AHO,-1.13633,0.0500837,0.00143563,1.08088 kka2_1:8_Q61C,kka2_1:8_61,Kka2,kka2_1:8,P00552,1.0809,NO,61,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.982,-5.1,2.118,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.100394,0.00612092,1.0809 kka2_1:8_Q61C,kka2_1:8_61,Kka2,kka2_1:8,P00552,1.0809,NO,61,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.982,-5.1,2.118,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.100394,0.00612092,1.0809 kka2_1:2_P249S,kka2_1:2_249,Kka2,kka2_1:2,P00552,1.08091,NO,249,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.867,-3.595,1.728,,0.406,.,B,0.52,-0.01,0.76,,92.05,HOA,-1.66867,0.295029,0.011045,1.08091 kka2_1:8_T125K,kka2_1:8_125,Kka2,kka2_1:8,P00552,1.08091,NO,125,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.622,-2.941,0.319,,0.791,T,A,0.22,0.33,2.675,,92.05,BPH,-1.56933,0.100394,0.00821755,1.08091 kka2_1:8_T125K,kka2_1:8_125,Kka2,kka2_1:8,P00552,1.08091,NO,125,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.622,-2.941,0.319,,0.791,T,A,0.22,0.33,2.675,,92.05,BPH,-1.56933,0.100394,0.00821755,1.08091 kka2_1:4_L165C,kka2_1:4_165,Kka2,kka2_1:4,P00552,1.08096,NO,165,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-2.453,-5.171,2.718,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.168804,0.00801161,1.08096 kka2_1:8_A71C,kka2_1:8_71,Kka2,kka2_1:8,P00552,1.08096,NO,71,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.824,-5.109,3.285,,0.553,H,A,0.46,0.08,18.64,18.64,64.39,HHP,-1.74033,0.100394,0.00727707,1.08096 kka2_1:8_A71C,kka2_1:8_71,Kka2,kka2_1:8,P00552,1.08096,NO,71,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.824,-5.109,3.285,,0.553,H,A,0.46,0.08,18.64,18.64,64.39,HHP,-1.74033,0.100394,0.00727707,1.08096 kka2_1:4_D154K,kka2_1:4_154,Kka2,kka2_1:4,P00552,1.081,NO,154,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.876,-3.46,2.584,,0.457,,b,0.29,1.48,15.641,15.641,52.65,HAP,-1.52467,0.168804,0.00292633,1.081 PSD95pdz3_L360R,PSD95pdz3_360,PSD95pdz3,PSD95pdz3,P31016,1.08103,NO,360,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.431,-3.614,2.183,5.09284,,,,,14.2425,1.419,,86.88,HHP,-1.52667,0.0758425,0.000770471,1.08103 PSD95pdz3_T321I,PSD95pdz3_321,PSD95pdz3,PSD95pdz3,P31016,1.08104,NO,321,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.391,-3.242,1.851,5.19953,,,,,20.3371,,,,PPO,-1.306,0.0758425,0.00106992,1.08104 kka2_1:1_A25Q,kka2_1:1_25,Kka2,kka2_1:1,P00552,1.08105,NO,25,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.496,-2.581,0.085,,0.427,E,B,0.46,-0.47,6.872,6.872,65.53,HHP,-2.15167,0.520039,0.00595636,1.08105 beta-lactamase_0_S266M,beta-lactamase_0_266,TEM-1,beta-lactamase_0,P62593,1.08107,NO,266,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.369,,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.0500837,0.0140785,1.08107 kka2_1:4_L193M,kka2_1:4_193,Kka2,kka2_1:4,P00552,1.08108,NO,193,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.983,-2.486,1.503,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.168804,0.00480179,1.08108 kka2_1:8_V113I,kka2_1:8_113,Kka2,kka2_1:8,P00552,1.08119,NO,113,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.233,-1.634,0.401,,0.008,H,A,1.48,-1.17,1.254,,52.27,BHP,-2.08367,0.100394,0.00650191,1.08119 kka2_1:8_V113I,kka2_1:8_113,Kka2,kka2_1:8,P00552,1.08119,NO,113,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.233,-1.634,0.401,,0.008,H,A,1.48,-1.17,1.254,,52.27,BHP,-2.08367,0.100394,0.00650191,1.08119 gb1_D248A,gb1_248,gb1,gb1,P06654,1.08126,NO,248,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.569,-2.72,1.151,,,,,,,0.344,,11.83,HAH,-1.673,0.177985,0.001865,1.08126 PSD95pdz3_I314S,PSD95pdz3_314,PSD95pdz3,PSD95pdz3,P31016,1.08126,NO,314,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.628,-3.388,1.76,5.39919,,,,,15.7775,0.397,,81.35,BHH,-1.61167,0.0758425,0.0012606,1.08126 PSD95pdz3_G356C,PSD95pdz3_356,PSD95pdz3,PSD95pdz3,P31016,1.08127,NO,356,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.008,-4.769,3.761,4.8656,,,,,11.9575,,,,BOA,-1.22933,0.0758425,0.000623061,1.08127 beta-lactamase_0_H94I,beta-lactamase_0_94,TEM-1,beta-lactamase_0,P62593,1.08128,NO,94,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-2.5,-2.913,0.413,,0.776,,B,0.17,1.24,1.176,,77.62,HBH,-1.872,0.0500837,0.00389226,1.08128 kka2_1:4_G55L,kka2_1:4_55,Kka2,kka2_1:4,P00552,1.08128,NO,55,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.625,-2.999,1.374,,0.517,S,b,0.75,1.19,15.753,15.753,63.64,POH,-2.05967,0.168804,0.00667877,1.08128 kka2_1:8_S11G,kka2_1:8_11,Kka2,kka2_1:8,P00552,1.08129,NO,11,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.322,-3.427,1.105,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.100394,0.00381691,1.08129 kka2_1:8_S11G,kka2_1:8_11,Kka2,kka2_1:8,P00552,1.08129,NO,11,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.322,-3.427,1.105,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.100394,0.00381691,1.08129 WW_domain_P172K,WW_domain_172,Yap65,WW_domain,P46937,1.08129,NO,172,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.035,-3.234,2.199,,,,,,,,,,HOH,-1.233,0.153962,0.000991485,1.08129 beta-lactamase_0_G281L,beta-lactamase_0_281,TEM-1,beta-lactamase_0,P62593,1.08131,NO,281,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.0500837,0.0406482,1.08131 PSD95pdz3_T387G,PSD95pdz3_387,PSD95pdz3,PSD95pdz3,P31016,1.08134,NO,387,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.391,-3.04,1.649,5.20757,,,,,18.8043,,,,HPH,-1.49533,0.0758425,0.000167911,1.08134 kka2_1:8_S54N,kka2_1:8_54,Kka2,kka2_1:8,P00552,1.08135,NO,54,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.471,-3.168,0.697,,0.408,S,b,0.77,1.01,13.679,13.679,71.59,HPO,-2.259,0.100394,0.00782867,1.08135 kka2_1:8_S54N,kka2_1:8_54,Kka2,kka2_1:8,P00552,1.08135,NO,54,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.471,-3.168,0.697,,0.408,S,b,0.77,1.01,13.679,13.679,71.59,HPO,-2.259,0.100394,0.00782867,1.08135 beta-lactamase_0_Q86K,beta-lactamase_0_86,TEM-1,beta-lactamase_0,P62593,1.08138,NO,86,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.4,-2.554,0.154,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.0500837,0.00450027,1.08138 kka2_1:4_E142R,kka2_1:4_142,Kka2,kka2_1:4,P00552,1.08143,NO,142,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.221,-2.483,0.262,,0.471,H,A,1.52,0.85,3.693,,65.53,HAB,-2.08033,0.168804,0.00748883,1.08143 kka2_1:8_A64Y,kka2_1:8_64,Kka2,kka2_1:8,P00552,1.08149,NO,64,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.496,-4.253,2.757,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.100394,0.00705578,1.08149 kka2_1:8_A64Y,kka2_1:8_64,Kka2,kka2_1:8,P00552,1.08149,NO,64,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.496,-4.253,2.757,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.100394,0.00705578,1.08149 kka2_1:8_Q26F,kka2_1:8_26,Kka2,kka2_1:8,P00552,1.08151,NO,26,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.18,-4.426,2.246,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.100394,0.00708962,1.08151 kka2_1:8_Q26F,kka2_1:8_26,Kka2,kka2_1:8,P00552,1.08151,NO,26,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.18,-4.426,2.246,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.100394,0.00708962,1.08151 gb1_D262A,gb1_262,gb1,gb1,P06654,1.08155,NO,262,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-3.132,-1.791,-1.341,,,,,,,1.304,,45.54,PAP,-2.05233,0.177985,0.00413102,1.08155 beta-lactamase_39_I93N,beta-lactamase_39_93,TEM-1,beta-lactamase_39,P62593,1.08159,NO,93,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.401,-4.175,2.774,,0.128,E,B,0.48,0.44,1.757,,67.83,BHB,-1.873,0.0495842,0.00527066,1.08159 gb1_D273N,gb1_273,gb1,gb1,P06654,1.08165,NO,273,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.998,-3.424,1.426,,,,,,,3.514,3.514,37.28,AAH,-1.72767,0.177985,0.00318903,1.08165 gb1_E268S,gb1_268,gb1,gb1,P06654,1.08165,NO,268,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.918,-3.109,1.191,,,,,,,0.637,,37.28,OAH,-1.59733,0.177985,0.00423953,1.08165 PSD95pdz3_S361I,PSD95pdz3_361,PSD95pdz3,PSD95pdz3,P31016,1.08165,NO,361,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.519,-3.467,1.948,4.8722,,,,,16.4533,,,,HPH,-1.47167,0.0758425,0.00055296,1.08165 WW_domain_Q186A,WW_domain_186,Yap65,WW_domain,P46937,1.08166,NO,186,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-1.358,-2.855,1.497,4.88854,,,,,,,,,OPB,-1.207,0.153962,0.00161546,1.08166 kka2_1:8_H139S,kka2_1:8_139,Kka2,kka2_1:8,P00552,1.08167,NO,139,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-2.809,-2.678,-0.131,,0.471,H,A,0.17,0.68,28.583,28.583,63.64,BBB,-2.22,0.100394,0.00734779,1.08167 kka2_1:8_H139S,kka2_1:8_139,Kka2,kka2_1:8,P00552,1.08167,NO,139,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-2.809,-2.678,-0.131,,0.471,H,A,0.17,0.68,28.583,28.583,63.64,BBB,-2.22,0.100394,0.00734779,1.08167 kka2_1:8_E231Y,kka2_1:8_231,Kka2,kka2_1:8,P00552,1.08168,NO,231,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.002,-4.332,2.33,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.100394,0.00732383,1.08168 kka2_1:8_E231Y,kka2_1:8_231,Kka2,kka2_1:8,P00552,1.08168,NO,231,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.002,-4.332,2.33,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.100394,0.00732383,1.08168 PSD95pdz3_I316C,PSD95pdz3_316,PSD95pdz3,PSD95pdz3,P31016,1.08171,NO,316,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.63,-4.319,2.689,5.46166,,,,,19.005,,,,HHB,-1.62733,0.0758425,0.00112762,1.08171 gb1_D262V,gb1_262,gb1,gb1,P06654,1.08175,NO,262,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-3.132,-3.28,0.148,,,,,,,1.304,,45.54,PAP,-2.05233,0.177985,0.00413102,1.08175 beta-lactamase_0_S57G,beta-lactamase_0_57,TEM-1,beta-lactamase_0,P62593,1.08177,NO,57,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.918,-2.176,0.258,,0.352,E,B,0.27,-0.18,1.454,,72.73,APH,-2.29167,0.0500837,0.00492804,1.08177 beta-lactamase_0_V260G,beta-lactamase_0_260,TEM-1,beta-lactamase_0,P62593,1.08181,NO,260,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.0500837,0.00471757,1.08181 gb1_E241Y,gb1_241,gb1,gb1,P06654,1.08184,NO,241,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.672,-3.973,2.301,,,,,,,0.344,,11.83,OAP,-1.27933,0.177985,0.00250604,1.08184 kka2_1:8_Q4R,kka2_1:8_4,Kka2,kka2_1:8,P00552,1.08187,NO,4,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.361,-3.443,1.082,,,,,,,2.026,,71.59,APA,-1.95533,0.100394,0.00239179,1.08187 kka2_1:8_Q4R,kka2_1:8_4,Kka2,kka2_1:8,P00552,1.08187,NO,4,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.361,-3.443,1.082,,,,,,,2.026,,71.59,APA,-1.95533,0.100394,0.00239179,1.08187 kka2_1:4_A110F,kka2_1:4_110,Kka2,kka2_1:4,P00552,1.08191,NO,110,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.064,-3.489,1.425,,0.175,H,A,0.46,-1.19,23.237,23.237,71.59,OHA,-1.91867,0.168804,0.00759851,1.08191 beta-lactamase_0_T27M,beta-lactamase_0_27,TEM-1,beta-lactamase_0,P62593,1.08193,NO,27,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.905,-4.581,2.676,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.0500837,0.00306559,1.08193 kka2_1:8_T130H,kka2_1:8_130,Kka2,kka2_1:8,P00552,1.08202,NO,130,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.392,-3.566,1.174,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.100394,0.00804204,1.08202 kka2_1:8_T130H,kka2_1:8_130,Kka2,kka2_1:8,P00552,1.08202,NO,130,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.392,-3.566,1.174,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.100394,0.00804204,1.08202 PSD95pdz3_N363E,PSD95pdz3_363,PSD95pdz3,PSD95pdz3,P31016,1.08202,NO,363,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-1.41,-2.897,1.487,5.23349,,,,,20.7037,,,,HPO,-1.29433,0.0758425,0.000524014,1.08202 beta-lactamase_0_R257F,beta-lactamase_0_257,TEM-1,beta-lactamase_0,P62593,1.08207,NO,257,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.0500837,0.00756629,1.08207 PSD95pdz3_V362C,PSD95pdz3_362,PSD95pdz3,PSD95pdz3,P31016,1.08208,NO,362,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.465,-4.319,2.854,4.99436,,,,,19.6443,,,,PHP,-1.46467,0.0758425,0.000538527,1.08208 PSD95pdz3_G335S,PSD95pdz3_335,PSD95pdz3,PSD95pdz3,P31016,1.08213,NO,335,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.008,-2.842,1.834,4.76223,,,,,22.4225,,,,AOH,-1.34733,0.0758425,0.000900493,1.08213 kka2_1:8_V83L,kka2_1:8_83,Kka2,kka2_1:8,P00552,1.0822,NO,83,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-2.567,-2.63,0.063,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.100394,0.00650486,1.0822 kka2_1:8_V83L,kka2_1:8_83,Kka2,kka2_1:8,P00552,1.0822,NO,83,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-2.567,-2.63,0.063,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.100394,0.00650486,1.0822 E1_Ubiquitin_T68S,E1_Ubiquitin_68,Uba1,E1_Ubiquitin,P0CG63,1.08223,NO,68,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,,,,,,,,,,,,,OPH,-1.039,0.18783,0.00314321,1.08223 beta-lactamase_0_Q88N,beta-lactamase_0_88,TEM-1,beta-lactamase_0,P62593,1.08226,NO,88,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.086,-2.735,0.649,,0.807,,B,0.64,2.03,0.4,,77.62,APH,-1.53433,0.0500837,0.00504167,1.08226 kka2_1:1_Q42R,kka2_1:1_42,Kka2,kka2_1:1,P00552,1.08228,NO,42,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.907,-3.056,0.149,,1.044,T,B,0.4,-0.8,2.792,,71.59,HPO,-2.12433,0.520039,0.00679212,1.08228 beta-lactamase_0_V157M,beta-lactamase_0_157,TEM-1,beta-lactamase_0,P62593,1.0823,NO,157,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.751,-2.587,0.836,,0.308,S,a,0.44,-0.75,3.106,,69.58,BHP,-2.00767,0.0500837,0.00506849,1.0823 kka2_1:8_I29S,kka2_1:8_29,Kka2,kka2_1:8,P00552,1.08232,NO,29,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.692,-3.624,1.932,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.100394,0.00619521,1.08232 kka2_1:8_I29S,kka2_1:8_29,Kka2,kka2_1:8,P00552,1.08232,NO,29,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.692,-3.624,1.932,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.100394,0.00619521,1.08232 kka2_1:8_D156S,kka2_1:8_156,Kka2,kka2_1:8,P00552,1.08247,NO,156,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.696,-2.049,0.353,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.100394,0.00926998,1.08247 kka2_1:8_D156S,kka2_1:8_156,Kka2,kka2_1:8,P00552,1.08247,NO,156,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.696,-2.049,0.353,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.100394,0.00926998,1.08247 kka2_1:8_R122L,kka2_1:8_122,Kka2,kka2_1:8,P00552,1.0825,NO,122,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.175,-3.603,1.428,,0.487,H,A,1.2,0.26,22.675,22.675,71.59,BBH,-1.53833,0.100394,0.00736512,1.0825 kka2_1:8_R122L,kka2_1:8_122,Kka2,kka2_1:8,P00552,1.0825,NO,122,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.175,-3.603,1.428,,0.487,H,A,1.2,0.26,22.675,22.675,71.59,BBH,-1.53833,0.100394,0.00736512,1.0825 beta-lactamase_39_V106Q,beta-lactamase_39_106,TEM-1,beta-lactamase_39,P62593,1.08253,NO,106,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.218,-4.248,3.03,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.0495842,0.00304168,1.08253 beta-lactamase_0_L218D,beta-lactamase_0_218,TEM-1,beta-lactamase_0,P62593,1.08254,NO,218,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.391,-3.905,2.514,,,I,b,0.55,-0.53,28.707,28.707,74.48,OHH,-1.58867,0.0500837,0.00618274,1.08254 kka2_1:8_A14G,kka2_1:8_14,Kka2,kka2_1:8,P00552,1.08259,NO,14,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.837,-2.323,0.486,,0.728,G,A,0.46,0.7,,,71.59,HHH,-1.82567,0.100394,0.00706614,1.08259 kka2_1:8_A14G,kka2_1:8_14,Kka2,kka2_1:8,P00552,1.08259,NO,14,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.837,-2.323,0.486,,0.728,G,A,0.46,0.7,,,71.59,HHH,-1.82567,0.100394,0.00706614,1.08259 kka2_1:8_R18C,kka2_1:8_18,Kka2,kka2_1:8,P00552,1.08259,NO,18,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.055,-5.174,3.119,,0.474,T,A,1.2,0.54,19.629,19.629,71.59,ABH,-1.821,0.100394,0.00724065,1.08259 kka2_1:8_R18C,kka2_1:8_18,Kka2,kka2_1:8,P00552,1.08259,NO,18,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.055,-5.174,3.119,,0.474,T,A,1.2,0.54,19.629,19.629,71.59,ABH,-1.821,0.100394,0.00724065,1.08259 kka2_1:8_A87F,kka2_1:8_87,Kka2,kka2_1:8,P00552,1.08263,NO,87,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.917,-4.449,2.532,,1.039,S,L,0.46,1.57,16.115,16.115,65.53,AHO,-1.822,0.100394,0.00791281,1.08263 kka2_1:8_A87F,kka2_1:8_87,Kka2,kka2_1:8,P00552,1.08263,NO,87,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.917,-4.449,2.532,,1.039,S,L,0.46,1.57,16.115,16.115,65.53,AHO,-1.822,0.100394,0.00791281,1.08263 kka2_1:8_A237I,kka2_1:8_237,Kka2,kka2_1:8,P00552,1.08266,NO,237,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.12,-2.296,0.176,,0.068,H,A,0.46,-0.71,0.449,,92.05,HHA,-2.10433,0.100394,0.012257,1.08266 kka2_1:8_A237I,kka2_1:8_237,Kka2,kka2_1:8,P00552,1.08266,NO,237,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.12,-2.296,0.176,,0.068,H,A,0.46,-0.71,0.449,,92.05,HHA,-2.10433,0.100394,0.012257,1.08266 beta-lactamase_0_A215C,beta-lactamase_0_215,TEM-1,beta-lactamase_0,P62593,1.08286,NO,215,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.503,-4.816,3.313,,,,a,0.46,-0.93,0.494,,74.48,HHO,-1.42633,0.0500837,0.00544007,1.08286 PSD95pdz3_S320V,PSD95pdz3_320,PSD95pdz3,PSD95pdz3,P31016,1.08287,NO,320,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.519,-3.21,1.691,5.81757,,,,,21.4517,,,,OPP,-1.306,0.0758425,0.00108158,1.08287 kka2_1:8_G55N,kka2_1:8_55,Kka2,kka2_1:8,P00552,1.08289,NO,55,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.625,-3.05,1.425,,0.517,S,b,0.29,1.19,8.881,,63.64,POH,-2.05967,0.100394,0.00667877,1.08289 kka2_1:8_G55N,kka2_1:8_55,Kka2,kka2_1:8,P00552,1.08289,NO,55,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.625,-3.05,1.425,,0.517,S,b,0.29,1.19,8.881,,63.64,POH,-2.05967,0.100394,0.00667877,1.08289 gb1_D262S,gb1_262,gb1,gb1,P06654,1.0829,NO,262,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-3.132,-2.152,-0.98,,,,,,,1.304,,45.54,PAP,-2.05233,0.177985,0.00413102,1.0829 kka2_1:8_E142T,kka2_1:8_142,Kka2,kka2_1:8,P00552,1.08296,NO,142,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.221,-2.837,0.616,,0.471,H,A,1.04,0.85,2.655,,65.53,HAB,-2.08033,0.100394,0.00748883,1.08296 kka2_1:8_E142T,kka2_1:8_142,Kka2,kka2_1:8,P00552,1.08296,NO,142,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.221,-2.837,0.616,,0.471,H,A,1.04,0.85,2.655,,65.53,HAB,-2.08033,0.100394,0.00748883,1.08296 PSD95pdz3_V315T,PSD95pdz3_315,PSD95pdz3,PSD95pdz3,P31016,1.08299,NO,315,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.625,-3.159,1.534,5.52024,,,,,18.4557,4.054,,81.35,HHH,-1.62767,0.0758425,0.00153536,1.08299 kka2_1:8_A56S,kka2_1:8_56,Kka2,kka2_1:8,P00552,1.08301,NO,56,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.083,-2.605,0.522,,0.796,T,A,0.46,1.39,10.511,,71.59,OHH,-1.86867,0.100394,0.00717715,1.08301 kka2_1:8_A56S,kka2_1:8_56,Kka2,kka2_1:8,P00552,1.08301,NO,56,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.083,-2.605,0.522,,0.796,T,A,0.46,1.39,10.511,,71.59,OHH,-1.86867,0.100394,0.00717715,1.08301 PSD95pdz3_N326V,PSD95pdz3_326,PSD95pdz3,PSD95pdz3,P31016,1.08305,NO,326,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-1.41,-3.435,2.025,5.52537,,,,,19.0688,,,,HPH,-1.52133,0.0758425,0.00101078,1.08305 beta-lactamase_39_W208M,beta-lactamase_39_208,TEM-1,beta-lactamase_39,P62593,1.08309,NO,208,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-0.818,-4.48,3.662,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.0495842,0.00126609,1.08309 kka2_1:8_D82E,kka2_1:8_82,Kka2,kka2_1:8,P00552,1.08309,NO,82,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.946,-2.436,0.49,,0.341,E,b,0.29,0.52,7.463,,63.64,HAH,-1.98,0.100394,0.00637516,1.08309 kka2_1:8_D82E,kka2_1:8_82,Kka2,kka2_1:8,P00552,1.08309,NO,82,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.946,-2.436,0.49,,0.341,E,b,0.29,0.52,7.463,,63.64,HAH,-1.98,0.100394,0.00637516,1.08309 gb1_T277Q,gb1_277,gb1,gb1,P06654,1.0831,NO,277,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.771,-3.796,2.025,,,,,,,0.824,,35.71,BPH,-1.54833,0.177985,0.00348258,1.0831 kka2_1:2_E230Y,kka2_1:2_230,Kka2,kka2_1:2,P00552,1.08313,NO,230,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.672,-2.09,-0.582,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.295029,0.00920051,1.08313 beta-lactamase_0_D113W,beta-lactamase_0_113,TEM-1,beta-lactamase_0,P62593,1.08315,NO,113,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.829,-5.545,3.716,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.0500837,0.00474112,1.08315 beta-lactamase_0_V82A,beta-lactamase_0_82,TEM-1,beta-lactamase_0,P62593,1.08316,NO,82,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.325,-2.13,0.805,,0.267,H,A,0.44,0.08,1.893,,93.01,BHA,-1.28567,0.0500837,0.00397046,1.08316 beta-lactamase_0_G236F,beta-lactamase_0_236,TEM-1,beta-lactamase_0,P62593,1.08319,NO,236,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.784,-4.291,3.507,,0.241,,b,0.29,-0.59,3.506,,64.69,HOO,-1.025,0.0500837,0.00162372,1.08319 gb1_T277H,gb1_277,gb1,gb1,P06654,1.08319,NO,277,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.771,-4.576,2.805,,,,,,,0.824,,35.71,BPH,-1.54833,0.177985,0.00348258,1.08319 PSD95pdz3_R313C,PSD95pdz3_313,PSD95pdz3,PSD95pdz3,P31016,1.0832,NO,313,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.582,-4.769,3.187,6.63563,,,,,18.3955,,,,BBH,-1.59733,0.0758425,0.000840067,1.0832 kka2_1:2_A176L,kka2_1:2_176,Kka2,kka2_1:2,P00552,1.08322,NO,176,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.621,-3.555,1.934,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.295029,0.0083587,1.08322 kka2_1:8_A247C,kka2_1:8_247,Kka2,kka2_1:8,P00552,1.08324,NO,247,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.459,-5.101,2.642,,1.01,S,A,0.46,0.65,18.904,18.904,92.05,HHH,-2.197,0.100394,0.0102428,1.08324 kka2_1:8_A247C,kka2_1:8_247,Kka2,kka2_1:8,P00552,1.08324,NO,247,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.459,-5.101,2.642,,1.01,S,A,0.46,0.65,18.904,18.904,92.05,HHH,-2.197,0.100394,0.0102428,1.08324 kka2_1:8_A108G,kka2_1:8_108,Kka2,kka2_1:8,P00552,1.08325,NO,108,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.061,-2.917,0.856,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.100394,0.00751209,1.08325 kka2_1:8_A108G,kka2_1:8_108,Kka2,kka2_1:8,P00552,1.08325,NO,108,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.061,-2.917,0.856,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.100394,0.00751209,1.08325 kka2_1:8_D227C,kka2_1:8_227,Kka2,kka2_1:8,P00552,1.08326,NO,227,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.758,-4.819,3.061,,0.128,H,A,0.75,-0.63,0.281,,56.06,BAH,-1.43067,0.100394,0.00745029,1.08326 kka2_1:8_D227C,kka2_1:8_227,Kka2,kka2_1:8,P00552,1.08326,NO,227,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.758,-4.819,3.061,,0.128,H,A,0.75,-0.63,0.281,,56.06,BAH,-1.43067,0.100394,0.00745029,1.08326 kka2_1:8_G43W,kka2_1:8_43,Kka2,kka2_1:8,P00552,1.08326,NO,43,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.587,-5.439,3.852,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.100394,0.0071925,1.08326 kka2_1:8_G43W,kka2_1:8_43,Kka2,kka2_1:8,P00552,1.08326,NO,43,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.587,-5.439,3.852,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.100394,0.0071925,1.08326 beta-lactamase_39_W208L,beta-lactamase_39_208,TEM-1,beta-lactamase_39,P62593,1.08333,NO,208,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,-0.818,-3.358,2.54,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.0495842,0.00126609,1.08333 beta-lactamase_0_G226R,beta-lactamase_0_226,TEM-1,beta-lactamase_0,P62593,1.08334,NO,226,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.461,-3.022,1.561,,0.701,T,l,0.29,-0.25,23.034,23.034,74.48,HOH,-1.42933,0.0500837,0.00665294,1.08334 kka2_1:8_M148Q,kka2_1:8_148,Kka2,kka2_1:8,P00552,1.0834,NO,148,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.847,-4.147,2.3,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.100394,0.00982664,1.0834 kka2_1:8_M148Q,kka2_1:8_148,Kka2,kka2_1:8,P00552,1.0834,NO,148,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.847,-4.147,2.3,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.100394,0.00982664,1.0834 beta-lactamase_0_N173I,beta-lactamase_0_173,TEM-1,beta-lactamase_0,P62593,1.08341,NO,173,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-2.663,-4.172,1.509,,1.044,T,l,0.61,1.25,1.133,,77.62,OPA,-1.46633,0.0500837,0.0033769,1.08341 PSD95pdz3_G333K,PSD95pdz3_333,PSD95pdz3,PSD95pdz3,P31016,1.08344,NO,333,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.008,-3.364,2.356,5.09445,,,,,48.755,,,,AOA,-1.22533,0.0758425,0.00092544,1.08344 kka2_1:2_D33S,kka2_1:2_33,Kka2,kka2_1:2,P00552,1.08346,NO,33,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.186,-2.451,0.265,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.295029,0.00633568,1.08346 PSD95pdz3_V315H,PSD95pdz3_315,PSD95pdz3,PSD95pdz3,P31016,1.08349,NO,315,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.625,-4.745,3.12,5.52024,,,,,18.4557,4.054,,81.35,HHH,-1.62767,0.0758425,0.00153536,1.08349 beta-lactamase_0_T27I,beta-lactamase_0_27,TEM-1,beta-lactamase_0,P62593,1.08351,NO,27,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.905,-3.752,1.847,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.0500837,0.00306559,1.08351 kka2_1:8_D227N,kka2_1:8_227,Kka2,kka2_1:8,P00552,1.08351,NO,227,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.758,-3.296,1.538,,0.128,H,A,0.75,-0.63,0.281,,56.06,BAH,-1.43067,0.100394,0.00745029,1.08351 kka2_1:8_D227N,kka2_1:8_227,Kka2,kka2_1:8,P00552,1.08351,NO,227,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.758,-3.296,1.538,,0.128,H,A,0.75,-0.63,0.281,,56.06,BAH,-1.43067,0.100394,0.00745029,1.08351 kka2_1:4_Y257F,kka2_1:4_257,Kka2,kka2_1:4,P00552,1.08352,NO,257,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-1.064,-1.664,0.6,,0.022,H,A,0.21,-0.88,1.053,,52.65,HHB,-1.39333,0.168804,0.0148191,1.08352 beta-lactamase_0_L167A,beta-lactamase_0_167,TEM-1,beta-lactamase_0,P62593,1.08354,NO,167,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.138,-3.097,1.959,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.0500837,0.00303566,1.08354 kka2_1:4_T28I,kka2_1:4_28,Kka2,kka2_1:4,P00552,1.08356,NO,28,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.883,-3.847,1.964,,0.353,S,B,0.82,2.02,4.415,,63.64,PPH,-1.74467,0.168804,0.00743084,1.08356 kka2_1:4_L93I,kka2_1:4_93,Kka2,kka2_1:4,P00552,1.08357,NO,93,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.815,-3.008,2.193,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.168804,0.00131498,1.08357 gb1_D266V,gb1_266,gb1,gb1,P06654,1.08358,NO,266,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.261,-3.443,2.182,,,,,,,0.638,,45.54,HAO,-1.59333,0.177985,0.00394694,1.08358 kka2_1:2_Q61H,kka2_1:2_61,Kka2,kka2_1:2,P00552,1.0836,NO,61,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.982,-4.796,1.814,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.295029,0.00612092,1.0836 kka2_1:8_Q4K,kka2_1:8_4,Kka2,kka2_1:8,P00552,1.08362,NO,4,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.361,-3.145,0.784,,,,,,,2.026,,71.59,APA,-1.95533,0.100394,0.00239179,1.08362 kka2_1:8_Q4K,kka2_1:8_4,Kka2,kka2_1:8,P00552,1.08362,NO,4,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.361,-3.145,0.784,,,,,,,2.026,,71.59,APA,-1.95533,0.100394,0.00239179,1.08362 kka2_1:8_A56M,kka2_1:8_56,Kka2,kka2_1:8,P00552,1.08363,NO,56,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.083,-4.776,2.693,,0.796,T,A,0.46,1.39,10.511,,71.59,OHH,-1.86867,0.100394,0.00717715,1.08363 kka2_1:8_A56M,kka2_1:8_56,Kka2,kka2_1:8,P00552,1.08363,NO,56,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.083,-4.776,2.693,,0.796,T,A,0.46,1.39,10.511,,71.59,OHH,-1.86867,0.100394,0.00717715,1.08363 kka2_1:8_A56T,kka2_1:8_56,Kka2,kka2_1:8,P00552,1.08368,NO,56,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.083,-2.626,0.543,,0.796,T,A,0.46,1.39,10.511,,71.59,OHH,-1.86867,0.100394,0.00717715,1.08368 kka2_1:8_A56T,kka2_1:8_56,Kka2,kka2_1:8,P00552,1.08368,NO,56,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.083,-2.626,0.543,,0.796,T,A,0.46,1.39,10.511,,71.59,OHH,-1.86867,0.100394,0.00717715,1.08368 kka2_1:8_G181L,kka2_1:8_181,Kka2,kka2_1:8,P00552,1.0837,NO,181,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-2.698,-3.595,0.897,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.100394,0.00728319,1.0837 kka2_1:8_G181L,kka2_1:8_181,Kka2,kka2_1:8,P00552,1.0837,NO,181,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-2.698,-3.595,0.897,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.100394,0.00728319,1.0837 WW_domain_Q186W,WW_domain_186,Yap65,WW_domain,P46937,1.08371,NO,186,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-1.358,-4.874,3.516,4.88854,,,,,,,,,OPB,-1.207,0.153962,0.00161546,1.08371 beta-lactamase_0_R92N,beta-lactamase_0_92,TEM-1,beta-lactamase_0,P62593,1.08374,NO,92,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.718,-2.988,1.27,,0.479,E,B,1.2,1.36,2.331,,65.38,BBH,-1.50367,0.0500837,0.00429626,1.08374 kka2_1:4_F37M,kka2_1:4_37,Kka2,kka2_1:4,P00552,1.08379,NO,37,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.427,-4.497,3.07,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.168804,0.00586193,1.08379 kka2_1:8_L212M,kka2_1:8_212,Kka2,kka2_1:8,P00552,1.08385,NO,212,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.904,-3.974,3.07,,,,B,1.59,-0.78,1.708,,42.42,BHO,-0.799667,0.100394,0.0031426,1.08385 kka2_1:8_L212M,kka2_1:8_212,Kka2,kka2_1:8,P00552,1.08385,NO,212,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.904,-3.974,3.07,,,,B,1.59,-0.78,1.708,,42.42,BHO,-0.799667,0.100394,0.0031426,1.08385 gb1_K239T,gb1_239,gb1,gb1,P06654,1.08386,NO,239,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-3.043,-2.889,-0.154,,,,,,,1.326,,45.54,HBO,-2.31467,0.177985,0.00207004,1.08386 beta-lactamase_0_M67T,beta-lactamase_0_67,TEM-1,beta-lactamase_0,P62593,1.08394,NO,67,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-2.231,-3.488,1.257,,0.006,G,P,0.55,-0.81,24.165,24.165,65.03,HHP,-1.502,0.0500837,0.00409753,1.08394 PSD95pdz3_E334D,PSD95pdz3_334,PSD95pdz3,PSD95pdz3,P31016,1.08398,NO,334,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.404,-2.475,1.071,5.60175,,,,,53.09,,,,OAO,-1.14,0.0758425,0.000912998,1.08398 beta-lactamase_0_M67S,beta-lactamase_0_67,TEM-1,beta-lactamase_0,P62593,1.084,NO,67,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-2.231,-2.445,0.214,,0.006,G,P,0.55,-0.81,24.165,24.165,65.03,HHP,-1.502,0.0500837,0.00409753,1.084 E1_Ubiquitin_A46K,E1_Ubiquitin_46,Uba1,E1_Ubiquitin,P0CG63,1.084,NO,46,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.367,-3.431,2.064,,0.398,T,L,,-0.8,,,,HHO,-1.17167,0.18783,0.004233,1.084 beta-lactamase_0_I258M,beta-lactamase_0_258,TEM-1,beta-lactamase_0,P62593,1.08404,NO,258,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.0500837,0.007931,1.08404 kka2_1:8_L57N,kka2_1:8_57,Kka2,kka2_1:8,P00552,1.08404,NO,57,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.898,-4.124,2.226,,0.343,T,A,0.55,0.98,13.359,13.359,52.65,HHP,-2.20733,0.100394,0.00723769,1.08404 kka2_1:8_L57N,kka2_1:8_57,Kka2,kka2_1:8,P00552,1.08404,NO,57,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.898,-4.124,2.226,,0.343,T,A,0.55,0.98,13.359,13.359,52.65,HHP,-2.20733,0.100394,0.00723769,1.08404 gb1_T277K,gb1_277,gb1,gb1,P06654,1.08405,NO,277,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.771,-3.394,1.623,,,,,,,0.824,,35.71,BPH,-1.54833,0.177985,0.00348258,1.08405 gb1_T277R,gb1_277,gb1,gb1,P06654,1.08405,NO,277,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.771,-3.752,1.981,,,,,,,0.824,,35.71,BPH,-1.54833,0.177985,0.00348258,1.08405 kka2_1:8_E17G,kka2_1:8_17,Kka2,kka2_1:8,P00552,1.08407,NO,17,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.154,-2.597,0.443,,0.957,T,A,1.04,0.22,31.483,31.483,63.64,HAB,-2.432,0.100394,0.00688738,1.08407 kka2_1:8_E17G,kka2_1:8_17,Kka2,kka2_1:8,P00552,1.08407,NO,17,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.154,-2.597,0.443,,0.957,T,A,1.04,0.22,31.483,31.483,63.64,HAB,-2.432,0.100394,0.00688738,1.08407 kka2_1:8_A129D,kka2_1:8_129,Kka2,kka2_1:8,P00552,1.08412,NO,129,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.656,-2.499,0.843,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.100394,0.00726862,1.08412 kka2_1:8_A129D,kka2_1:8_129,Kka2,kka2_1:8,P00552,1.08412,NO,129,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.656,-2.499,0.843,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.100394,0.00726862,1.08412 kka2_1:4_A172V,kka2_1:4_172,Kka2,kka2_1:4,P00552,1.08418,NO,172,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.757,-2.683,0.926,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.168804,0.0079265,1.08418 gb1_E241H,gb1_241,gb1,gb1,P06654,1.08424,NO,241,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.672,-4.241,2.569,,,,,,,0.344,,11.83,OAP,-1.27933,0.177985,0.00250604,1.08424 kka2_1:4_R202T,kka2_1:4_202,Kka2,kka2_1:4,P00552,1.08427,NO,202,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.761,-3.676,1.915,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.168804,0.00696498,1.08427 beta-lactamase_39_I171Q,beta-lactamase_39_171,TEM-1,beta-lactamase_39,P62593,1.08428,NO,171,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-2.431,-3.168,0.737,,0.361,,B,0.48,0.53,16.954,16.954,77.62,HHO,-1.55533,0.0495842,0.00623355,1.08428 kka2_1:2_A14E,kka2_1:2_14,Kka2,kka2_1:2,P00552,1.08429,NO,14,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.837,-3.519,1.682,,0.728,G,A,0.46,0.7,0.36,,71.59,HHH,-1.82567,0.295029,0.00706614,1.08429 PSD95pdz3_V315W,PSD95pdz3_315,PSD95pdz3,PSD95pdz3,P31016,1.08436,NO,315,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.625,-5.093,3.468,5.52024,,,,,18.4557,4.054,,81.35,HHH,-1.62767,0.0758425,0.00153536,1.08436 kka2_1:4_Y218L,kka2_1:4_218,Kka2,kka2_1:4,P00552,1.08438,NO,218,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-1.438,-3.412,1.974,,0.122,H,A,0.21,-0.69,1.022,,56.06,BHP,-1.17533,0.168804,0.0126098,1.08438 kka2_1:8_Q219I,kka2_1:8_219,Kka2,kka2_1:8,P00552,1.08439,NO,219,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-0.93,-4.062,3.132,,0.088,H,A,0.4,-0.85,0.897,,50,HPA,-1.05167,0.100394,0.00237913,1.08439 kka2_1:8_Q219I,kka2_1:8_219,Kka2,kka2_1:8,P00552,1.08439,NO,219,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-0.93,-4.062,3.132,,0.088,H,A,0.4,-0.85,0.897,,50,HPA,-1.05167,0.100394,0.00237913,1.08439 kka2_1:8_A41T,kka2_1:8_41,Kka2,kka2_1:8,P00552,1.08452,NO,41,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.879,-3.68,1.801,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.100394,0.00543332,1.08452 kka2_1:8_A41T,kka2_1:8_41,Kka2,kka2_1:8,P00552,1.08452,NO,41,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.879,-3.68,1.801,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.100394,0.00543332,1.08452 kka2_1:4_T51Q,kka2_1:4_51,Kka2,kka2_1:4,P00552,1.08463,NO,51,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.199,-3.313,1.114,,0.05,E,B,0.82,-0.05,13.165,13.165,63.64,BPA,-1.76767,0.168804,0.00628861,1.08463 kka2_1:8_Q163G,kka2_1:8_163,Kka2,kka2_1:8,P00552,1.08463,NO,163,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.162,-3.698,1.536,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.100394,0.00719507,1.08463 kka2_1:8_Q163G,kka2_1:8_163,Kka2,kka2_1:8,P00552,1.08463,NO,163,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.162,-3.698,1.536,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.100394,0.00719507,1.08463 beta-lactamase_0_M209V,beta-lactamase_0_209,TEM-1,beta-lactamase_0,P62593,1.08464,NO,209,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.442,-2.446,1.004,,,H,A,0.55,-0.97,3.876,,64.69,HHA,-1.52633,0.0500837,0.00625021,1.08464 kka2_1:8_P45S,kka2_1:8_45,Kka2,kka2_1:8,P00552,1.0847,NO,45,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.774,-2.464,0.69,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.100394,0.00590481,1.0847 kka2_1:8_P45S,kka2_1:8_45,Kka2,kka2_1:8,P00552,1.0847,NO,45,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.774,-2.464,0.69,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.100394,0.00590481,1.0847 PSD95pdz3_T321A,PSD95pdz3_321,PSD95pdz3,PSD95pdz3,P31016,1.08476,NO,321,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.391,-2.534,1.143,5.19953,,,,,20.3371,,,,PPO,-1.306,0.0758425,0.00106992,1.08476 kka2_1:8_P128I,kka2_1:8_128,Kka2,kka2_1:8,P00552,1.08489,NO,128,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.922,-1.808,-0.114,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.100394,0.00774689,1.08489 kka2_1:8_P128I,kka2_1:8_128,Kka2,kka2_1:8,P00552,1.08489,NO,128,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.922,-1.808,-0.114,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.100394,0.00774689,1.08489 kka2_1:2_A255K,kka2_1:2_255,Kka2,kka2_1:2,P00552,1.08491,NO,255,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.715,-2.818,1.103,,0.466,H,A,0.46,-0.52,5.144,,65.53,HHH,-1.71267,0.295029,0.0126809,1.08491 beta-lactamase_0_R41H,beta-lactamase_0_41,TEM-1,beta-lactamase_0,P62593,1.08494,NO,41,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-0.942,-4.279,3.337,,0.321,E,B,1.2,-0.07,2.68,,65.03,HBH,-1.30267,0.0500837,0.00123327,1.08494 kka2_1:2_A247I,kka2_1:2_247,Kka2,kka2_1:2,P00552,1.08495,NO,247,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.459,-3.148,0.689,,1.01,S,A,0.46,0.65,0.828,,92.05,HHH,-2.197,0.295029,0.0102428,1.08495 kka2_1:8_A255R,kka2_1:8_255,Kka2,kka2_1:8,P00552,1.08504,NO,255,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.715,-2.777,1.062,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.100394,0.0126809,1.08504 kka2_1:8_A255R,kka2_1:8_255,Kka2,kka2_1:8,P00552,1.08504,NO,255,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.715,-2.777,1.062,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.100394,0.0126809,1.08504 beta-lactamase_0_R91N,beta-lactamase_0_91,TEM-1,beta-lactamase_0,P62593,1.08505,NO,91,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.392,-3.596,2.204,,0.444,,B,1.2,0.96,4.557,,50.35,OBB,-1.73367,0.0500837,0.00380226,1.08505 kka2_1:8_P128A,kka2_1:8_128,Kka2,kka2_1:8,P00552,1.08506,NO,128,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.922,-2.593,0.671,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.100394,0.00774689,1.08506 kka2_1:8_P128A,kka2_1:8_128,Kka2,kka2_1:8,P00552,1.08506,NO,128,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.922,-2.593,0.671,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.100394,0.00774689,1.08506 kka2_1:8_R173Y,kka2_1:8_173,Kka2,kka2_1:8,P00552,1.08509,NO,173,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.407,-3.028,0.621,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.100394,0.00784999,1.08509 kka2_1:8_R173Y,kka2_1:8_173,Kka2,kka2_1:8,P00552,1.08509,NO,173,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.407,-3.028,0.621,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.100394,0.00784999,1.08509 kka2_1:1_P167L,kka2_1:1_167,Kka2,kka2_1:1,P00552,1.08514,NO,167,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-2.403,-2.565,0.162,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.520039,0.00543203,1.08514 beta-lactamase_0_L284C,beta-lactamase_0_284,TEM-1,beta-lactamase_0,P62593,1.08518,NO,284,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.981,,,,0.848,H,A,2.89,0.67,4.544,,77.62,PHH,-1.82133,0.0500837,0.0686156,1.08518 kka2_1:8_L93M,kka2_1:8_93,Kka2,kka2_1:8,P00552,1.08522,NO,93,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.815,-3.907,3.092,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.100394,0.00131498,1.08522 kka2_1:8_L93M,kka2_1:8_93,Kka2,kka2_1:8,P00552,1.08522,NO,93,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.815,-3.907,3.092,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.100394,0.00131498,1.08522 kka2_1:8_E169L,kka2_1:8_169,Kka2,kka2_1:8,P00552,1.08525,NO,169,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.996,-3.06,1.064,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.100394,0.00730086,1.08525 kka2_1:8_E169L,kka2_1:8_169,Kka2,kka2_1:8,P00552,1.08525,NO,169,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.996,-3.06,1.064,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.100394,0.00730086,1.08525 gb1_L233I,gb1_233,gb1,gb1,P06654,1.08529,NO,233,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-2.678,-2.116,-0.562,,,,,,,0.822,,45.54,HHP,-2.30267,0.177985,0.00266958,1.08529 kka2_1:4_V83L,kka2_1:4_83,Kka2,kka2_1:4,P00552,1.08538,NO,83,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-2.567,-2.63,0.063,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.168804,0.00650486,1.08538 beta-lactamase_0_G39M,beta-lactamase_0_39,TEM-1,beta-lactamase_0,P62593,1.08544,NO,39,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.864,-4.879,3.015,,0.701,T,L,0.29,0.47,4.111,,77.62,HOH,-1.53633,0.0500837,0.00487611,1.08544 kka2_1:4_E169V,kka2_1:4_169,Kka2,kka2_1:4,P00552,1.08553,NO,169,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.996,-3.701,1.705,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.168804,0.00730086,1.08553 gb1_D262R,gb1_262,gb1,gb1,P06654,1.08557,NO,262,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-3.132,-3.379,0.247,,,,,,,1.304,,45.54,PAP,-2.05233,0.177985,0.00413102,1.08557 beta-lactamase_0_R189T,beta-lactamase_0_189,TEM-1,beta-lactamase_0,P62593,1.08559,NO,189,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.844,-3.622,1.778,,0.278,H,A,1.2,1.01,12.11,12.11,72.73,HBB,-1.668,0.0500837,0.0050699,1.08559 kka2_1:8_S114G,kka2_1:8_114,Kka2,kka2_1:8,P00552,1.08568,NO,114,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.527,-2.602,0.075,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.100394,0.00705262,1.08568 kka2_1:8_S114G,kka2_1:8_114,Kka2,kka2_1:8,P00552,1.08568,NO,114,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.527,-2.602,0.075,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.100394,0.00705262,1.08568 kka2_1:8_N200D,kka2_1:8_200,Kka2,kka2_1:8,P00552,1.0857,NO,200,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-2.446,-2.235,-0.211,,0.756,T,L,0.43,-0.08,2.528,,64.39,APO,-2.08,0.100394,0.00838549,1.0857 kka2_1:8_N200D,kka2_1:8_200,Kka2,kka2_1:8,P00552,1.0857,NO,200,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-2.446,-2.235,-0.211,,0.756,T,L,0.43,-0.08,2.528,,64.39,APO,-2.08,0.100394,0.00838549,1.0857 kka2_1:8_G201A,kka2_1:8_201,Kka2,kka2_1:8,P00552,1.08571,NO,201,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.56,-3.247,1.687,,0.149,T,l,0.75,-0.57,2.152,,52.65,POB,-1.92233,0.100394,0.00820117,1.08571 kka2_1:8_G201A,kka2_1:8_201,Kka2,kka2_1:8,P00552,1.08571,NO,201,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.56,-3.247,1.687,,0.149,T,l,0.75,-0.57,2.152,,52.65,POB,-1.92233,0.100394,0.00820117,1.08571 kka2_1:8_A247I,kka2_1:8_247,Kka2,kka2_1:8,P00552,1.08577,NO,247,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.459,-3.148,0.689,,1.01,S,A,0.46,0.65,18.904,18.904,92.05,HHH,-2.197,0.100394,0.0102428,1.08577 kka2_1:8_A247I,kka2_1:8_247,Kka2,kka2_1:8,P00552,1.08577,NO,247,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.459,-3.148,0.689,,1.01,S,A,0.46,0.65,18.904,18.904,92.05,HHH,-2.197,0.100394,0.0102428,1.08577 beta-lactamase_0_N130C,beta-lactamase_0_130,TEM-1,beta-lactamase_0,P62593,1.0858,NO,130,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-0.798,-5.087,4.289,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.0500837,0.000683376,1.0858 beta-lactamase_0_G234M,beta-lactamase_0_234,TEM-1,beta-lactamase_0,P62593,1.08582,NO,234,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.62,-4.93,4.31,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.0500837,0.000889577,1.08582 beta-lactamase_0_E61D,beta-lactamase_0_61,TEM-1,beta-lactamase_0,P62593,1.08585,NO,61,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.115,-1.402,-0.713,,0.775,T,a,1.04,1.29,34.763,34.763,77.62,OAA,-1.92567,0.0500837,0.00440955,1.08585 gb1_D273Q,gb1_273,gb1,gb1,P06654,1.08586,NO,273,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.998,-3.574,1.576,,,,,,,3.514,3.514,37.28,AAH,-1.72767,0.177985,0.00318903,1.08586 beta-lactamase_39_M209W,beta-lactamase_39_209,TEM-1,beta-lactamase_39,P62593,1.08592,NO,209,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.442,-4.979,3.537,,,H,A,0.55,-0.97,1.167,,64.69,HHA,-1.52633,0.0495842,0.00625021,1.08592 PSD95pdz3_V315L,PSD95pdz3_315,PSD95pdz3,PSD95pdz3,P31016,1.08601,NO,315,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.625,-1.782,0.157,5.52024,,,,,18.4557,4.054,,81.35,HHH,-1.62767,0.0758425,0.00153536,1.08601 kka2_1:4_T146F,kka2_1:4_146,Kka2,kka2_1:4,P00552,1.08605,NO,146,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.978,-4.333,1.355,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.168804,0.00606474,1.08605 beta-lactamase_39_I171E,beta-lactamase_39_171,TEM-1,beta-lactamase_39,P62593,1.08606,NO,171,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-2.431,-3.643,1.212,,0.361,,B,0.48,0.53,16.954,16.954,77.62,HHO,-1.55533,0.0495842,0.00623355,1.08606 kka2_1:8_A64H,kka2_1:8_64,Kka2,kka2_1:8,P00552,1.08606,NO,64,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.496,-4.947,3.451,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.100394,0.00705578,1.08606 kka2_1:8_A64H,kka2_1:8_64,Kka2,kka2_1:8,P00552,1.08606,NO,64,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.496,-4.947,3.451,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.100394,0.00705578,1.08606 beta-lactamase_39_V106M,beta-lactamase_39_106,TEM-1,beta-lactamase_39,P62593,1.08609,NO,106,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.218,-3.026,1.808,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.0495842,0.00304168,1.08609 kka2_1:8_T125A,kka2_1:8_125,Kka2,kka2_1:8,P00552,1.08611,NO,125,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.622,-1.886,-0.736,,0.791,T,A,0.22,0.33,2.675,,92.05,BPH,-1.56933,0.100394,0.00821755,1.08611 kka2_1:8_T125A,kka2_1:8_125,Kka2,kka2_1:8,P00552,1.08611,NO,125,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.622,-1.886,-0.736,,0.791,T,A,0.22,0.33,2.675,,92.05,BPH,-1.56933,0.100394,0.00821755,1.08611 beta-lactamase_0_I258R,beta-lactamase_0_258,TEM-1,beta-lactamase_0,P62593,1.08617,NO,258,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.0500837,0.007931,1.08617 kka2_1:4_P12S,kka2_1:4_12,Kka2,kka2_1:4,P00552,1.08617,NO,12,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.853,-3.336,2.483,,,,B,0.52,1.25,0.843,,48.11,POH,-1.80767,0.168804,0.00500011,1.08617 beta-lactamase_0_A148S,beta-lactamase_0_148,TEM-1,beta-lactamase_0,P62593,1.08618,NO,148,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.757,-2.791,1.034,,0.379,H,A,0.46,-0.55,19.42,19.42,72.73,PHH,-1.40167,0.0500837,0.00547053,1.08618 kka2_1:8_L259C,kka2_1:8_259,Kka2,kka2_1:8,P00552,1.08618,NO,259,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.088,-4.727,3.639,,0.036,H,A,1.59,-0.15,1.83,,48.48,BHH,-1.15167,0.100394,0.0206964,1.08618 kka2_1:8_L259C,kka2_1:8_259,Kka2,kka2_1:8,P00552,1.08618,NO,259,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.088,-4.727,3.639,,0.036,H,A,1.59,-0.15,1.83,,48.48,BHH,-1.15167,0.100394,0.0206964,1.08618 kka2_1:4_A41R,kka2_1:4_41,Kka2,kka2_1:4,P00552,1.08621,NO,41,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.879,-2.71,0.831,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.168804,0.00543332,1.08621 beta-lactamase_0_K109F,beta-lactamase_0_109,TEM-1,beta-lactamase_0,P62593,1.08628,NO,109,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.734,-4.437,2.703,,0.787,G,A,2.34,2.21,15.473,15.473,72.73,ABB,-1.63333,0.0500837,0.00462493,1.08628 beta-lactamase_39_M209G,beta-lactamase_39_209,TEM-1,beta-lactamase_39,P62593,1.08637,NO,209,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.442,-3.732,2.29,,,H,A,0.55,-0.97,1.167,,64.69,HHA,-1.52633,0.0495842,0.00625021,1.08637 beta-lactamase_0_H94T,beta-lactamase_0_94,TEM-1,beta-lactamase_0,P62593,1.08639,NO,94,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-2.5,-2.6,0.1,,0.776,,B,0.17,1.24,1.176,,77.62,HBH,-1.872,0.0500837,0.00389226,1.08639 kka2_1:4_A150V,kka2_1:4_150,Kka2,kka2_1:4,P00552,1.08642,NO,150,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.949,-3.306,2.357,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.168804,0.0045009,1.08642 beta-lactamase_0_A247S,beta-lactamase_0_247,TEM-1,beta-lactamase_0,P62593,1.08649,NO,247,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.0500837,0.00611275,1.08649 kka2_1:8_R38H,kka2_1:8_38,Kka2,kka2_1:8,P00552,1.08649,NO,38,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.207,-4.545,3.338,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.100394,0.00372499,1.08649 kka2_1:8_R38H,kka2_1:8_38,Kka2,kka2_1:8,P00552,1.08649,NO,38,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.207,-4.545,3.338,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.100394,0.00372499,1.08649 kka2_1:4_I29R,kka2_1:4_29,Kka2,kka2_1:4,P00552,1.0865,NO,29,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.692,-4.083,2.391,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.168804,0.00619521,1.0865 beta-lactamase_0_S201P,beta-lactamase_0_201,TEM-1,beta-lactamase_0,P62593,1.08655,NO,201,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.183,-3.79,2.607,,0.064,H,A,0.27,-0.07,3.54,,64.69,HPB,-1.451,0.0500837,0.00198815,1.08655 beta-lactamase_39_F228N,beta-lactamase_39_228,TEM-1,beta-lactamase_39,P62593,1.08655,NO,228,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-2.342,-3.038,0.696,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.0495842,0.0046669,1.08655 PSD95pdz3_R312Q,PSD95pdz3_312,PSD95pdz3,PSD95pdz3,P31016,1.08663,NO,312,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.582,-3.131,1.549,5.76826,,,,,12.2409,,,,OBB,-1.46667,0.0758425,0.00196255,1.08663 kka2_1:8_I254H,kka2_1:8_254,Kka2,kka2_1:8,P00552,1.08669,NO,254,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.933,-4.91,2.977,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.100394,0.0132375,1.08669 kka2_1:8_I254H,kka2_1:8_254,Kka2,kka2_1:8,P00552,1.08669,NO,254,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.933,-4.91,2.977,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.100394,0.0132375,1.08669 kka2_1:8_P128M,kka2_1:8_128,Kka2,kka2_1:8,P00552,1.08676,NO,128,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.922,-4.47,2.548,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.100394,0.00774689,1.08676 kka2_1:8_P128M,kka2_1:8_128,Kka2,kka2_1:8,P00552,1.08676,NO,128,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.922,-4.47,2.548,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.100394,0.00774689,1.08676 kka2_1:8_Q136R,kka2_1:8_136,Kka2,kka2_1:8,P00552,1.08683,NO,136,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-3.021,-1.428,-1.593,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.100394,0.00624149,1.08683 kka2_1:8_Q136R,kka2_1:8_136,Kka2,kka2_1:8,P00552,1.08683,NO,136,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-3.021,-1.428,-1.593,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.100394,0.00624149,1.08683 gb1_D273A,gb1_273,gb1,gb1,P06654,1.08689,NO,273,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.998,-2.194,0.196,,,,,,,3.514,3.514,37.28,AAH,-1.72767,0.177985,0.00318903,1.08689 WW_domain_Q200R,WW_domain_200,Yap65,WW_domain,P46937,1.08689,NO,200,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-1.599,-2.167,0.568,5.37476,,,,,,1.9,,70.04,HPA,-1.484,0.153962,0.00300397,1.08689 kka2_1:4_E142P,kka2_1:4_142,Kka2,kka2_1:4,P00552,1.0869,NO,142,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.221,-2.43,0.209,,0.471,H,A,1.52,0.85,3.693,,65.53,HAB,-2.08033,0.168804,0.00748883,1.0869 beta-lactamase_0_K109L,beta-lactamase_0_109,TEM-1,beta-lactamase_0,P62593,1.08692,NO,109,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.734,-2.969,1.235,,0.787,G,A,2.34,2.21,15.473,15.473,72.73,ABB,-1.63333,0.0500837,0.00462493,1.08692 kka2_1:8_E111S,kka2_1:8_111,Kka2,kka2_1:8,P00552,1.08694,NO,111,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.28,-2.706,0.426,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.100394,0.00746789,1.08694 kka2_1:8_E111S,kka2_1:8_111,Kka2,kka2_1:8,P00552,1.08694,NO,111,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.28,-2.706,0.426,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.100394,0.00746789,1.08694 kka2_1:8_F133Y,kka2_1:8_133,Kka2,kka2_1:8,P00552,1.08694,NO,133,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-0.871,-2.422,1.551,,0.178,,B,1.62,0.43,1.816,,42.42,OHA,-0.871667,0.100394,0.00182168,1.08694 kka2_1:8_F133Y,kka2_1:8_133,Kka2,kka2_1:8,P00552,1.08694,NO,133,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-0.871,-2.422,1.551,,0.178,,B,1.62,0.43,1.816,,42.42,OHA,-0.871667,0.100394,0.00182168,1.08694 kka2_1:8_T28K,kka2_1:8_28,Kka2,kka2_1:8,P00552,1.08699,NO,28,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.883,-3.68,1.797,,0.353,S,B,0.22,2.02,18.114,18.114,63.64,PPH,-1.74467,0.100394,0.00743084,1.08699 kka2_1:8_T28K,kka2_1:8_28,Kka2,kka2_1:8,P00552,1.08699,NO,28,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.883,-3.68,1.797,,0.353,S,B,0.22,2.02,18.114,18.114,63.64,PPH,-1.74467,0.100394,0.00743084,1.08699 beta-lactamase_0_A182G,beta-lactamase_0_182,TEM-1,beta-lactamase_0,P62593,1.08701,NO,182,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.777,-3.408,1.631,,0.136,H,A,0.46,-0.66,10.765,10.765,93.01,OHH,-1.27367,0.0500837,0.00559099,1.08701 kka2_1:4_D227S,kka2_1:4_227,Kka2,kka2_1:4,P00552,1.08701,NO,227,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.758,-1.053,-0.705,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.168804,0.00745029,1.08701 kka2_1:8_R145H,kka2_1:8_145,Kka2,kka2_1:8,P00552,1.08703,NO,145,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.804,-3.445,1.641,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.100394,0.00846663,1.08703 kka2_1:8_R145H,kka2_1:8_145,Kka2,kka2_1:8,P00552,1.08703,NO,145,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.804,-3.445,1.641,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.100394,0.00846663,1.08703 kka2_1:4_D52A,kka2_1:4_52,Kka2,kka2_1:4,P00552,1.0871,NO,52,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.271,-3.15,0.879,,0.22,E,B,0.75,0.8,0.349,,71.59,PAH,-2.38367,0.168804,0.00175694,1.0871 kka2_1:2_A129S,kka2_1:2_129,Kka2,kka2_1:2,P00552,1.08711,NO,129,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.656,-2.58,0.924,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.295029,0.00726862,1.08711 kka2_1:2_L19V,kka2_1:2_19,Kka2,kka2_1:2,P00552,1.08711,NO,19,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.254,-2.596,1.342,,0.08,T,A,0.55,-0.26,17.165,17.165,65.53,BHH,-2.221,0.295029,0.00620703,1.08711 kka2_1:8_E96T,kka2_1:8_96,Kka2,kka2_1:8,P00552,1.08714,NO,96,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.573,-2.511,-0.062,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.100394,0.00369441,1.08714 kka2_1:8_E96T,kka2_1:8_96,Kka2,kka2_1:8,P00552,1.08714,NO,96,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.573,-2.511,-0.062,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.100394,0.00369441,1.08714 kka2_1:8_D227E,kka2_1:8_227,Kka2,kka2_1:8,P00552,1.08722,NO,227,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.758,-3.138,1.38,,0.128,H,A,0.75,-0.63,0.281,,56.06,BAH,-1.43067,0.100394,0.00745029,1.08722 kka2_1:8_D227E,kka2_1:8_227,Kka2,kka2_1:8,P00552,1.08722,NO,227,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.758,-3.138,1.38,,0.128,H,A,0.75,-0.63,0.281,,56.06,BAH,-1.43067,0.100394,0.00745029,1.08722 kka2_1:4_G55R,kka2_1:4_55,Kka2,kka2_1:4,P00552,1.08725,NO,55,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.625,-4.045,2.42,,0.517,S,b,0.75,1.19,15.753,15.753,63.64,POH,-2.05967,0.168804,0.00667877,1.08725 PSD95pdz3_G333C,PSD95pdz3_333,PSD95pdz3,PSD95pdz3,P31016,1.08731,NO,333,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.008,-4.769,3.761,5.09445,,,,,48.755,,,,AOA,-1.22533,0.0758425,0.00092544,1.08731 kka2_1:4_S40W,kka2_1:4_40,Kka2,kka2_1:4,P00552,1.08734,NO,40,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.645,-5.57,2.925,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.168804,0.00693477,1.08734 PSD95pdz3_Q391F,PSD95pdz3_391,PSD95pdz3,PSD95pdz3,P31016,1.08735,NO,391,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-1.699,-3.974,2.275,5.50275,,,,,12.6589,,,,HPH,-1.481,0.0758425,0.000990786,1.08735 gb1_T277W,gb1_277,gb1,gb1,P06654,1.08736,NO,277,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.771,-5.219,3.448,,,,,,,0.824,,35.71,BPH,-1.54833,0.177985,0.00348258,1.08736 kka2_1:8_P98G,kka2_1:8_98,Kka2,kka2_1:8,P00552,1.08736,NO,98,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.526,-3.498,1.972,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.100394,0.00622754,1.08736 kka2_1:8_P98G,kka2_1:8_98,Kka2,kka2_1:8,P00552,1.08736,NO,98,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.526,-3.498,1.972,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.100394,0.00622754,1.08736 beta-lactamase_0_L191T,beta-lactamase_0_191,TEM-1,beta-lactamase_0,P62593,1.08737,NO,191,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.087,-3.447,2.36,,,H,A,0.55,0.09,12.255,12.255,63.29,BHH,-1.445,0.0500837,0.00263549,1.08737 kka2_1:8_L174T,kka2_1:8_174,Kka2,kka2_1:8,P00552,1.08741,NO,174,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.952,-3.474,2.522,,,H,A,1.59,-0.31,1.204,,51.89,BHB,-2.08533,0.100394,0.00438501,1.08741 kka2_1:8_L174T,kka2_1:8_174,Kka2,kka2_1:8,P00552,1.08741,NO,174,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.952,-3.474,2.522,,,H,A,1.59,-0.31,1.204,,51.89,BHB,-2.08533,0.100394,0.00438501,1.08741 beta-lactamase_0_Q86R,beta-lactamase_0_86,TEM-1,beta-lactamase_0,P62593,1.08744,NO,86,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.4,-2.686,0.286,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.0500837,0.00450027,1.08744 kka2_1:2_N58T,kka2_1:2_58,Kka2,kka2_1:2,P00552,1.08746,NO,58,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-2.641,-2.933,0.292,,0.131,S,A,0.43,0.72,5.729,,71.59,HPA,-1.83033,0.295029,0.00793425,1.08746 beta-lactamase_0_T193D,beta-lactamase_0_193,TEM-1,beta-lactamase_0,P62593,1.08748,NO,193,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.914,-3.815,1.901,,0.439,H,a,0.22,0.33,11.546,11.546,63.99,HPO,-1.52133,0.0500837,0.00482669,1.08748 kka2_1:4_T28F,kka2_1:4_28,Kka2,kka2_1:4,P00552,1.08751,NO,28,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.883,-4.355,2.472,,0.353,S,B,0.82,2.02,4.415,,63.64,PPH,-1.74467,0.168804,0.00743084,1.08751 beta-lactamase_0_R239P,beta-lactamase_0_239,TEM-1,beta-lactamase_0,P62593,1.08756,NO,239,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.0500837,0.00213852,1.08756 kka2_1:2_Q42R,kka2_1:2_42,Kka2,kka2_1:2,P00552,1.08757,NO,42,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.907,-3.056,0.149,,1.044,T,B,0.64,-0.8,2.792,,71.59,HPO,-2.12433,0.295029,0.00679212,1.08757 kka2_1:8_E161Q,kka2_1:8_161,Kka2,kka2_1:8,P00552,1.08757,NO,161,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.581,-3.792,2.211,,0.829,G,A,1.04,2.24,11.923,11.923,92.05,AAB,-1.861,0.100394,0.00760103,1.08757 kka2_1:8_E161Q,kka2_1:8_161,Kka2,kka2_1:8,P00552,1.08757,NO,161,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.581,-3.792,2.211,,0.829,G,A,1.04,2.24,11.923,11.923,92.05,AAB,-1.861,0.100394,0.00760103,1.08757 kka2_1:8_D134N,kka2_1:8_134,Kka2,kka2_1:8,P00552,1.08762,NO,134,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.969,-2.658,1.689,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.100394,0.00270812,1.08762 kka2_1:8_D134N,kka2_1:8_134,Kka2,kka2_1:8,P00552,1.08762,NO,134,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.969,-2.658,1.689,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.100394,0.00270812,1.08762 kka2_1:2_E142L,kka2_1:2_142,Kka2,kka2_1:2,P00552,1.08763,NO,142,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.221,-3.056,0.835,,0.471,H,A,1.52,0.85,3.693,,65.53,HAB,-2.08033,0.295029,0.00748883,1.08763 PSD95pdz3_Y392N,PSD95pdz3_392,PSD95pdz3,PSD95pdz3,P31016,1.08764,NO,392,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-1.437,-3.58,2.143,5.20337,,,,,11.725,,,,PHB,-1.51733,0.0758425,0.000935211,1.08764 beta-lactamase_625_D212N,beta-lactamase_625_212,TEM-1,beta-lactamase_625,P62593,1.08767,NO,212,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.624,-1.899,0.275,,0.037,,b,0.75,-0.58,1.516,,74.48,HAB,-1.77667,0.213352,0.00644302,1.08767 kka2_1:8_R122H,kka2_1:8_122,Kka2,kka2_1:8,P00552,1.08772,NO,122,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.175,-3.287,1.112,,0.487,H,A,1.2,0.26,22.675,22.675,71.59,BBH,-1.53833,0.100394,0.00736512,1.08772 kka2_1:8_R122H,kka2_1:8_122,Kka2,kka2_1:8,P00552,1.08772,NO,122,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.175,-3.287,1.112,,0.487,H,A,1.2,0.26,22.675,22.675,71.59,BBH,-1.53833,0.100394,0.00736512,1.08772 WW_domain_R187P,WW_domain_187,Yap65,WW_domain,P46937,1.08778,NO,187,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.402,-3.65,2.248,5.05189,,,,,,3.431,,78.57,PBH,-1.362,0.153962,0.00171149,1.08778 beta-lactamase_0_E164R,beta-lactamase_0_164,TEM-1,beta-lactamase_0,P62593,1.08786,NO,164,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-0.948,-3.511,2.563,,0.011,T,B,1.04,-0.4,1.011,,64.69,HAO,-1.388,0.0500837,0.00137286,1.08786 kka2_1:8_N200M,kka2_1:8_200,Kka2,kka2_1:8,P00552,1.08787,NO,200,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-2.446,-4.957,2.511,,0.756,T,L,0.43,-0.08,2.528,,64.39,APO,-2.08,0.100394,0.00838549,1.08787 kka2_1:8_N200M,kka2_1:8_200,Kka2,kka2_1:8,P00552,1.08787,NO,200,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-2.446,-4.957,2.511,,0.756,T,L,0.43,-0.08,2.528,,64.39,APO,-2.08,0.100394,0.00838549,1.08787 WW_domain_M179Q,WW_domain_179,Yap65,WW_domain,P46937,1.08787,NO,179,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.541,-3.451,1.91,6.54704,,,,,,,,,AHH,-1.31367,0.153962,0.00400164,1.08787 kka2_1:2_F171W,kka2_1:2_171,Kka2,kka2_1:2,P00552,1.08788,NO,171,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.326,-4.742,3.416,,0.154,H,A,0.58,-0.1,2.645,,63.64,HHH,-1.45433,0.295029,0.00821426,1.08788 PSD95pdz3_S361L,PSD95pdz3_361,PSD95pdz3,PSD95pdz3,P31016,1.08792,NO,361,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.519,-3.04,1.521,4.8722,,,,,16.4533,,,,HPH,-1.47167,0.0758425,0.00055296,1.08792 beta-lactamase_39_I171P,beta-lactamase_39_171,TEM-1,beta-lactamase_39,P62593,1.08796,NO,171,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-2.431,-4.052,1.621,,0.361,,B,0.48,0.53,16.954,16.954,77.62,HHO,-1.55533,0.0495842,0.00623355,1.08796 kka2_1:8_G95D,kka2_1:8_95,Kka2,kka2_1:8,P00552,1.08798,NO,95,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-2.403,-2.891,0.488,,0.126,E,B,0.75,-0.74,7.774,,71.59,HOA,-2.198,0.100394,0.00743616,1.08798 kka2_1:8_G95D,kka2_1:8_95,Kka2,kka2_1:8,P00552,1.08798,NO,95,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-2.403,-2.891,0.488,,0.126,E,B,0.75,-0.74,7.774,,71.59,HOA,-2.198,0.100394,0.00743616,1.08798 kka2_1:2_A41D,kka2_1:2_41,Kka2,kka2_1:2,P00552,1.08801,NO,41,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.879,-3.164,1.285,,0.184,.,B,0.46,-0.96,24.451,24.451,64.39,PHP,-2.477,0.295029,0.00543332,1.08801 beta-lactamase_0_K232V,beta-lactamase_0_232,TEM-1,beta-lactamase_0,P62593,1.08805,NO,232,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.012,-3.626,2.614,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.0500837,0.00313441,1.08805 PSD95pdz3_N326M,PSD95pdz3_326,PSD95pdz3,PSD95pdz3,P31016,1.08808,NO,326,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-1.41,-4.387,2.977,5.52537,,,,,19.0688,,,,HPH,-1.52133,0.0758425,0.00101078,1.08808 PSD95pdz3_G335K,PSD95pdz3_335,PSD95pdz3,PSD95pdz3,P31016,1.08813,NO,335,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.008,-3.364,2.356,4.76223,,,,,22.4225,,,,AOH,-1.34733,0.0758425,0.000900493,1.08813 beta-lactamase_0_L196P,beta-lactamase_0_196,TEM-1,beta-lactamase_0,P62593,1.08815,NO,196,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-2.478,-3.165,0.687,,0.518,S,A,0.55,1.35,6.513,6.513,77.62,AHH,-1.839,0.0500837,0.00512144,1.08815 beta-lactamase_0_I285R,beta-lactamase_0_285,TEM-1,beta-lactamase_0,P62593,1.08816,NO,285,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.0500837,0.101555,1.08816 beta-lactamase_0_N50M,beta-lactamase_0_50,TEM-1,beta-lactamase_0,P62593,1.08828,NO,50,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-2.979,-4.727,1.748,,0.912,T,A,0.61,1.24,9.874,9.874,77.62,HPP,-2.134,0.0500837,0.0047211,1.08828 kka2_1:4_K175A,kka2_1:4_175,Kka2,kka2_1:4,P00552,1.08828,NO,175,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-2.897,-2.718,-0.179,,0.579,H,A,1.3,0.51,15.629,15.629,71.59,HBH,-1.82333,0.168804,0.00693093,1.08828 beta-lactamase_0_L219A,beta-lactamase_0_219,TEM-1,beta-lactamase_0,P62593,1.08832,NO,219,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.313,-3.187,1.874,,,I,A,0.55,-0.51,6.513,6.513,74.48,HHB,-1.21533,0.0500837,0.00664345,1.08832 kka2_1:4_P76H,kka2_1:4_76,Kka2,kka2_1:4,P00552,1.08834,NO,76,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.449,-4.835,3.386,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.168804,0.00625685,1.08834 kka2_1:4_T51M,kka2_1:4_51,Kka2,kka2_1:4,P00552,1.08842,NO,51,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.199,-4.634,2.435,,0.05,E,B,0.82,-0.05,13.165,13.165,63.64,BPA,-1.76767,0.168804,0.00628861,1.08842 kka2_1:8_P167G,kka2_1:8_167,Kka2,kka2_1:8,P00552,1.08844,NO,167,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-2.403,-3.388,0.985,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.100394,0.00543203,1.08844 kka2_1:8_P167G,kka2_1:8_167,Kka2,kka2_1:8,P00552,1.08844,NO,167,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-2.403,-3.388,0.985,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.100394,0.00543203,1.08844 beta-lactamase_0_Q86V,beta-lactamase_0_86,TEM-1,beta-lactamase_0,P62593,1.08845,NO,86,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.4,-2.988,0.588,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.0500837,0.00450027,1.08845 beta-lactamase_0_K213L,beta-lactamase_0_213,TEM-1,beta-lactamase_0,P62593,1.08855,NO,213,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.81,-3.558,1.748,,0.67,,A,2.34,0.29,3.015,,67.83,ABH,-1.57767,0.0500837,0.00610411,1.08855 kka2_1:8_L7P,kka2_1:8_7,Kka2,kka2_1:8,P00552,1.08855,NO,7,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.926,-3.817,1.891,,,,,,,,,71.59,OHB,-2.12333,0.100394,0.00269456,1.08855 kka2_1:8_L7P,kka2_1:8_7,Kka2,kka2_1:8,P00552,1.08855,NO,7,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.926,-3.817,1.891,,,,,,,,,71.59,OHB,-2.12333,0.100394,0.00269456,1.08855 PSD95pdz3_E334L,PSD95pdz3_334,PSD95pdz3,PSD95pdz3,P31016,1.08855,NO,334,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.404,-3.265,1.861,5.60175,,,,,53.09,,,,OAO,-1.14,0.0758425,0.000912998,1.08855 beta-lactamase_0_T269S,beta-lactamase_0_269,TEM-1,beta-lactamase_0,P62593,1.08856,NO,269,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.0500837,0.00950944,1.08856 kka2_1:2_A129Q,kka2_1:2_129,Kka2,kka2_1:2,P00552,1.08856,NO,129,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.656,-3.989,2.333,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.295029,0.00726862,1.08856 gb1_E268M,gb1_268,gb1,gb1,P06654,1.08857,NO,268,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.918,-4.464,2.546,,,,,,,0.637,,37.28,OAH,-1.59733,0.177985,0.00423953,1.08857 kka2_1:4_N58K,kka2_1:4_58,Kka2,kka2_1:4,P00552,1.08862,NO,58,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-2.641,-3.669,1.028,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.168804,0.00793425,1.08862 kka2_1:8_A56C,kka2_1:8_56,Kka2,kka2_1:8,P00552,1.08862,NO,56,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.083,-5.094,3.011,,0.796,T,A,0.46,1.39,10.511,,71.59,OHH,-1.86867,0.100394,0.00717715,1.08862 kka2_1:8_A56C,kka2_1:8_56,Kka2,kka2_1:8,P00552,1.08862,NO,56,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.083,-5.094,3.011,,0.796,T,A,0.46,1.39,10.511,,71.59,OHH,-1.86867,0.100394,0.00717715,1.08862 kka2_1:2_A166P,kka2_1:2_166,Kka2,kka2_1:2,P00552,1.08864,NO,166,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.407,-2.34,-0.067,,0.534,.,B,0.46,1.03,23.175,23.175,71.59,HHO,-2.421,0.295029,0.00799912,1.08864 beta-lactamase_0_R189M,beta-lactamase_0_189,TEM-1,beta-lactamase_0,P62593,1.08867,NO,189,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.844,-4.718,2.874,,0.278,H,A,1.2,1.01,12.11,12.11,72.73,HBB,-1.668,0.0500837,0.0050699,1.08867 beta-lactamase_0_T193H,beta-lactamase_0_193,TEM-1,beta-lactamase_0,P62593,1.0887,NO,193,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.914,-4.78,2.866,,0.439,H,a,0.22,0.33,11.546,11.546,63.99,HPO,-1.52133,0.0500837,0.00482669,1.0887 beta-lactamase_2500_A211M,beta-lactamase_2500_211,TEM-1,beta-lactamase_2500,P62593,1.0887,NO,211,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.896,-3.437,1.541,,0.369,T,A,0.46,-0.69,2.061,,77.62,AHA,-1.94633,0.361275,0.00648183,1.0887 kka2_1:8_H8G,kka2_1:8_8,Kka2,kka2_1:8,P00552,1.08871,NO,8,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-2.759,-2.248,-0.511,,,,,,,,,71.59,HBH,-2.25467,0.100394,0.00256422,1.08871 kka2_1:8_H8G,kka2_1:8_8,Kka2,kka2_1:8,P00552,1.08871,NO,8,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-2.759,-2.248,-0.511,,,,,,,,,71.59,HBH,-2.25467,0.100394,0.00256422,1.08871 kka2_1:4_A168E,kka2_1:4_168,Kka2,kka2_1:4,P00552,1.08878,NO,168,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.989,-2.167,0.178,,0.67,H,A,0.46,0.15,,,64.39,OHA,-2.12933,0.168804,0.00806773,1.08878 kka2_1:8_C209G,kka2_1:8_209,Kka2,kka2_1:8,P00552,1.08883,NO,209,C,G,CG,Special,Special,5.07,3.29388,-1.77612,159,121,75,-46,108.5,60.1,-48.4,-0.906,-3.655,2.749,,,,a,1.5,-0.89,0.391,,19.32,AOO,-0.903,0.100394,0.00260862,1.08883 kka2_1:8_C209G,kka2_1:8_209,Kka2,kka2_1:8,P00552,1.08883,NO,209,C,G,CG,Special,Special,5.07,3.29388,-1.77612,159,121,75,-46,108.5,60.1,-48.4,-0.906,-3.655,2.749,,,,a,1.5,-0.89,0.391,,19.32,AOO,-0.903,0.100394,0.00260862,1.08883 kka2_1:8_G43K,kka2_1:8_43,Kka2,kka2_1:8,P00552,1.08884,NO,43,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.587,-3.606,2.019,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.100394,0.0071925,1.08884 kka2_1:8_G43K,kka2_1:8_43,Kka2,kka2_1:8,P00552,1.08884,NO,43,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.587,-3.606,2.019,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.100394,0.0071925,1.08884 kka2_1:8_Q4P,kka2_1:8_4,Kka2,kka2_1:8,P00552,1.08885,NO,4,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.361,-3.662,1.301,,,,,,,2.026,,71.59,APA,-1.95533,0.100394,0.00239179,1.08885 kka2_1:8_Q4P,kka2_1:8_4,Kka2,kka2_1:8,P00552,1.08885,NO,4,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.361,-3.662,1.301,,,,,,,2.026,,71.59,APA,-1.95533,0.100394,0.00239179,1.08885 kka2_1:4_Y218C,kka2_1:4_218,Kka2,kka2_1:4,P00552,1.08887,NO,218,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-1.438,-2.974,1.536,,0.122,H,A,0.21,-0.69,1.022,,56.06,BHP,-1.17533,0.168804,0.0126098,1.08887 kka2_1:8_E199F,kka2_1:8_199,Kka2,kka2_1:8,P00552,1.08897,NO,199,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.234,-4.372,2.138,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.100394,0.00854122,1.08897 kka2_1:8_E199F,kka2_1:8_199,Kka2,kka2_1:8,P00552,1.08897,NO,199,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.234,-4.372,2.138,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.100394,0.00854122,1.08897 kka2_1:8_A255S,kka2_1:8_255,Kka2,kka2_1:8,P00552,1.089,NO,255,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.715,-2.589,0.874,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.100394,0.0126809,1.089 kka2_1:8_A255S,kka2_1:8_255,Kka2,kka2_1:8,P00552,1.089,NO,255,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.715,-2.589,0.874,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.100394,0.0126809,1.089 kka2_1:2_V214I,kka2_1:2_214,Kka2,kka2_1:2,P00552,1.08903,NO,214,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.261,-1.849,0.588,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.295029,0.00692782,1.08903 beta-lactamase_0_I244V,beta-lactamase_0_244,TEM-1,beta-lactamase_0,P62593,1.08905,NO,244,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.555,-1.239,-0.316,,,E,B,0.48,-0.84,1.241,,77.62,OHH,-1.385,0.0500837,0.00605379,1.08905 kka2_1:8_Q61W,kka2_1:8_61,Kka2,kka2_1:8,P00552,1.08907,NO,61,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.982,-5.59,2.608,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.100394,0.00612092,1.08907 kka2_1:8_Q61W,kka2_1:8_61,Kka2,kka2_1:8,P00552,1.08907,NO,61,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.982,-5.59,2.608,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.100394,0.00612092,1.08907 PSD95pdz3_T321G,PSD95pdz3_321,PSD95pdz3,PSD95pdz3,P31016,1.08908,NO,321,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.391,-3.04,1.649,5.19953,,,,,20.3371,,,,PPO,-1.306,0.0758425,0.00106992,1.08908 kka2_1:4_S104N,kka2_1:4_104,Kka2,kka2_1:4,P00552,1.08911,NO,104,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.436,-2.903,1.467,,0.536,T,A,0.27,-1.11,0.357,,63.64,HPP,-1.91433,0.168804,0.00555207,1.08911 gb1_D273Y,gb1_273,gb1,gb1,P06654,1.08913,NO,273,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.998,-4.205,2.207,,,,,,,3.514,3.514,37.28,AAH,-1.72767,0.177985,0.00318903,1.08913 beta-lactamase_0_L146D,beta-lactamase_0_146,TEM-1,beta-lactamase_0,P62593,1.08917,NO,146,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.462,-4.108,2.646,,0.007,H,A,0.55,-0.56,2.051,,64.69,AHP,-1.656,0.0500837,0.00474542,1.08917 kka2_1:4_V80F,kka2_1:4_80,Kka2,kka2_1:4,P00552,1.08922,NO,80,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.144,-3.963,2.819,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.168804,0.00488211,1.08922 beta-lactamase_0_H24M,beta-lactamase_0_24,TEM-1,beta-lactamase_0,P62593,1.08923,NO,24,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-2.481,-3.144,0.663,,,,,,,2.708,,93.01,OBO,-2.0035,0.0500837,0.00238894,1.08923 PSD95pdz3_T321M,PSD95pdz3_321,PSD95pdz3,PSD95pdz3,P31016,1.08933,NO,321,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.391,-4.162,2.771,5.19953,,,,,20.3371,,,,PPO,-1.306,0.0758425,0.00106992,1.08933 kka2_1:8_V242H,kka2_1:8_242,Kka2,kka2_1:8,P00552,1.08947,NO,242,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-2.687,-3.504,0.817,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.100394,0.0102575,1.08947 kka2_1:8_V242H,kka2_1:8_242,Kka2,kka2_1:8,P00552,1.08947,NO,242,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-2.687,-3.504,0.817,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.100394,0.0102575,1.08947 kka2_1:8_M197V,kka2_1:8_197,Kka2,kka2_1:8,P00552,1.08951,NO,197,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.707,-2.226,0.519,,0.121,E,B,1.59,-1.19,4.408,,65.53,HHH,-1.847,0.100394,0.00921295,1.08951 kka2_1:8_M197V,kka2_1:8_197,Kka2,kka2_1:8,P00552,1.08951,NO,197,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.707,-2.226,0.519,,0.121,E,B,1.59,-1.19,4.408,,65.53,HHH,-1.847,0.100394,0.00921295,1.08951 kka2_1:8_S114K,kka2_1:8_114,Kka2,kka2_1:8,P00552,1.08951,NO,114,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.527,-3.596,1.069,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.100394,0.00705262,1.08951 kka2_1:8_S114K,kka2_1:8_114,Kka2,kka2_1:8,P00552,1.08951,NO,114,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.527,-3.596,1.069,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.100394,0.00705262,1.08951 PSD95pdz3_T321C,PSD95pdz3_321,PSD95pdz3,PSD95pdz3,P31016,1.08951,NO,321,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.391,-4.319,2.928,5.19953,,,,,20.3371,,,,PPO,-1.306,0.0758425,0.00106992,1.08951 PSD95pdz3_S361F,PSD95pdz3_361,PSD95pdz3,PSD95pdz3,P31016,1.08952,NO,361,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.519,-3.749,2.23,4.8722,,,,,16.4533,,,,HPH,-1.47167,0.0758425,0.00055296,1.08952 kka2_1:4_A255E,kka2_1:4_255,Kka2,kka2_1:4,P00552,1.08953,NO,255,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.715,-2.621,0.906,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.168804,0.0126809,1.08953 PSD95pdz3_T321H,PSD95pdz3_321,PSD95pdz3,PSD95pdz3,P31016,1.08953,NO,321,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.391,-4.362,2.971,5.19953,,,,,20.3371,,,,PPO,-1.306,0.0758425,0.00106992,1.08953 beta-lactamase_0_V260I,beta-lactamase_0_260,TEM-1,beta-lactamase_0,P62593,1.08957,NO,260,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.0500837,0.00471757,1.08957 kka2_1:8_E86H,kka2_1:8_86,Kka2,kka2_1:8,P00552,1.08964,NO,86,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.86,-2.283,0.423,,0.369,,B,1.52,1.92,,,63.26,PAH,-1.98067,0.100394,0.00642858,1.08964 kka2_1:8_E86H,kka2_1:8_86,Kka2,kka2_1:8,P00552,1.08964,NO,86,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.86,-2.283,0.423,,0.369,,B,1.52,1.92,,,63.26,PAH,-1.98067,0.100394,0.00642858,1.08964 beta-lactamase_0_G216Y,beta-lactamase_0_216,TEM-1,beta-lactamase_0,P62593,1.08967,NO,216,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.477,-4.44,2.963,,0.437,I,A,0.29,-0.58,0.834,,74.48,HOO,-1.68067,0.0500837,0.00639568,1.08967 kka2_1:8_A79L,kka2_1:8_79,Kka2,kka2_1:8,P00552,1.08969,NO,79,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.368,-3.577,1.209,,0.563,.,B,0.46,-0.43,,,71.59,HHH,-1.752,0.100394,0.00664821,1.08969 kka2_1:8_A79L,kka2_1:8_79,Kka2,kka2_1:8,P00552,1.08969,NO,79,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.368,-3.577,1.209,,0.563,.,B,0.46,-0.43,,,71.59,HHH,-1.752,0.100394,0.00664821,1.08969 PSD95pdz3_S361R,PSD95pdz3_361,PSD95pdz3,PSD95pdz3,P31016,1.0897,NO,361,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.519,-3.39,1.871,4.8722,,,,,16.4533,,,,HPH,-1.47167,0.0758425,0.00055296,1.0897 beta-lactamase_39_P224K,beta-lactamase_39_224,TEM-1,beta-lactamase_39,P62593,1.08971,NO,224,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.893,-3.389,2.496,,0.383,,B,0.52,-0.3,3.169,,74.48,HOH,-1.26433,0.0495842,0.00189564,1.08971 kka2_1:2_V242L,kka2_1:2_242,Kka2,kka2_1:2,P00552,1.08971,NO,242,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-2.687,-3.55,0.863,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.295029,0.0102575,1.08971 beta-lactamase_0_L120R,beta-lactamase_0_120,TEM-1,beta-lactamase_0,P62593,1.08973,NO,120,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.044,-2.871,1.827,,,H,A,0.55,-1.13,1.2,,64.69,AHO,-1.13633,0.0500837,0.00143563,1.08973 kka2_1:2_I246C,kka2_1:2_246,Kka2,kka2_1:2,P00552,1.08974,NO,246,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-2.008,-4.975,2.967,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.295029,0.0139479,1.08974 beta-lactamase_0_E108P,beta-lactamase_0_108,TEM-1,beta-lactamase_0,P62593,1.08977,NO,108,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.46,-3.855,2.395,,0.572,G,A,1.04,1.87,8.602,8.602,72.73,PAB,-1.437,0.0500837,0.00413372,1.08977 kka2_1:8_L81Q,kka2_1:8_81,Kka2,kka2_1:8,P00552,1.0898,NO,81,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.427,-3.189,1.762,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.100394,0.00805839,1.0898 kka2_1:8_L81Q,kka2_1:8_81,Kka2,kka2_1:8,P00552,1.0898,NO,81,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.427,-3.189,1.762,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.100394,0.00805839,1.0898 PSD95pdz3_V315A,PSD95pdz3_315,PSD95pdz3,PSD95pdz3,P31016,1.08988,NO,315,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.625,-2.815,1.19,5.52024,,,,,18.4557,4.054,,81.35,HHH,-1.62767,0.0758425,0.00153536,1.08988 kka2_1:8_R239T,kka2_1:8_239,Kka2,kka2_1:8,P00552,1.08993,NO,239,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.949,-3.616,0.667,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.100394,0.00835326,1.08993 kka2_1:8_R239T,kka2_1:8_239,Kka2,kka2_1:8,P00552,1.08993,NO,239,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.949,-3.616,0.667,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.100394,0.00835326,1.08993 beta-lactamase_0_A215V,beta-lactamase_0_215,TEM-1,beta-lactamase_0,P62593,1.08997,NO,215,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.503,-3.464,1.961,,,,a,0.46,-0.93,0.494,,74.48,HHO,-1.42633,0.0500837,0.00544007,1.08997 kka2_1:8_S54G,kka2_1:8_54,Kka2,kka2_1:8,P00552,1.09,NO,54,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.471,-2.892,0.421,,0.408,S,b,0.77,1.01,13.679,13.679,71.59,HPO,-2.259,0.100394,0.00782867,1.09 kka2_1:8_S54G,kka2_1:8_54,Kka2,kka2_1:8,P00552,1.09,NO,54,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.471,-2.892,0.421,,0.408,S,b,0.77,1.01,13.679,13.679,71.59,HPO,-2.259,0.100394,0.00782867,1.09 beta-lactamase_0_R189S,beta-lactamase_0_189,TEM-1,beta-lactamase_0,P62593,1.09003,NO,189,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.844,-2.849,1.005,,0.278,H,A,1.2,1.01,12.11,12.11,72.73,HBB,-1.668,0.0500837,0.0050699,1.09003 kka2_1:4_S204M,kka2_1:4_204,Kka2,kka2_1:4,P00552,1.09003,NO,204,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.353,-4.656,3.303,,0.144,E,A,0.27,-1.2,2.442,,65.53,HPO,-0.953333,0.168804,0.00881794,1.09003 beta-lactamase_0_R189P,beta-lactamase_0_189,TEM-1,beta-lactamase_0,P62593,1.09004,NO,189,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.844,-3.964,2.12,,0.278,H,A,1.2,1.01,12.11,12.11,72.73,HBB,-1.668,0.0500837,0.0050699,1.09004 beta-lactamase_0_G90E,beta-lactamase_0_90,TEM-1,beta-lactamase_0,P62593,1.09007,NO,90,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-2.091,-2.175,0.084,,0.598,T,A,0.29,0.32,2.04,,77.62,HOB,-1.52633,0.0500837,0.00490273,1.09007 beta-lactamase_0_F58P,beta-lactamase_0_58,TEM-1,beta-lactamase_0,P62593,1.0901,NO,58,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-2.914,-4.147,1.233,,0.266,E,B,0.58,-0.07,24.637,24.637,77.62,PHB,-2.059,0.0500837,0.00523369,1.0901 PSD95pdz3_S320C,PSD95pdz3_320,PSD95pdz3,PSD95pdz3,P31016,1.09016,NO,320,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.519,-4.319,2.8,5.81757,,,,,21.4517,,,,OPP,-1.306,0.0758425,0.00108158,1.09016 beta-lactamase_0_E210S,beta-lactamase_0_210,TEM-1,beta-lactamase_0,P62593,1.09021,NO,210,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.319,-2.669,0.35,,0.476,H,A,1.04,0.75,3.618,,77.62,HAH,-1.88567,0.0500837,0.00663582,1.09021 beta-lactamase_0_A77R,beta-lactamase_0_77,TEM-1,beta-lactamase_0,P62593,1.09024,NO,77,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.234,-3.891,2.657,,0.039,H,A,0.46,-0.56,2.591,,64.34,OHH,-1.294,0.0500837,0.00282362,1.09024 kka2_1:8_E160V,kka2_1:8_160,Kka2,kka2_1:8,P00552,1.09027,NO,160,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.683,-3.733,2.05,,0.989,G,A,1.04,2.28,2.164,,71.59,AAA,-1.36133,0.100394,0.00935762,1.09027 kka2_1:8_E160V,kka2_1:8_160,Kka2,kka2_1:8,P00552,1.09027,NO,160,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.683,-3.733,2.05,,0.989,G,A,1.04,2.28,2.164,,71.59,AAA,-1.36133,0.100394,0.00935762,1.09027 beta-lactamase_0_N50H,beta-lactamase_0_50,TEM-1,beta-lactamase_0,P62593,1.09032,NO,50,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-2.979,-3.33,0.351,,0.912,T,A,0.61,1.24,9.874,9.874,77.62,HPP,-2.134,0.0500837,0.0047211,1.09032 kka2_1:8_M178D,kka2_1:8_178,Kka2,kka2_1:8,P00552,1.09034,NO,178,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-3.206,-3.894,0.688,,0.554,,b,1.59,0.68,13.268,13.268,71.59,BHO,-2.154,0.100394,0.00717253,1.09034 kka2_1:8_M178D,kka2_1:8_178,Kka2,kka2_1:8,P00552,1.09034,NO,178,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-3.206,-3.894,0.688,,0.554,,b,1.59,0.68,13.268,13.268,71.59,BHO,-2.154,0.100394,0.00717253,1.09034 kka2_1:4_G74R,kka2_1:4_74,Kka2,kka2_1:4,P00552,1.09047,NO,74,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.18,-3.943,2.763,,0.621,T,l,0.75,0.2,1.032,,64.39,POH,-1.91667,0.168804,0.00587035,1.09047 kka2_1:4_I254N,kka2_1:4_254,Kka2,kka2_1:4,P00552,1.09048,NO,254,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.933,-4.208,2.275,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.168804,0.0132375,1.09048 beta-lactamase_0_A278E,beta-lactamase_0_278,TEM-1,beta-lactamase_0,P62593,1.09053,NO,278,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.348,,,,0.015,H,A,0.48,-0.85,4.624,,63.29,HHA,-1.41833,0.0500837,0.0310297,1.09053 kka2_1:8_I141M,kka2_1:8_141,Kka2,kka2_1:8,P00552,1.09054,NO,141,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.495,-2.864,1.369,,0.068,H,A,1.52,-0.01,2.144,,92.05,BHA,-1.689,0.100394,0.00744745,1.09054 kka2_1:8_I141M,kka2_1:8_141,Kka2,kka2_1:8,P00552,1.09054,NO,141,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.495,-2.864,1.369,,0.068,H,A,1.52,-0.01,2.144,,92.05,BHA,-1.689,0.100394,0.00744745,1.09054 kka2_1:2_A14S,kka2_1:2_14,Kka2,kka2_1:2,P00552,1.09056,NO,14,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.837,-2.532,0.695,,0.728,G,A,0.46,0.7,0.36,,71.59,HHH,-1.82567,0.295029,0.00706614,1.09056 kka2_1:4_A9C,kka2_1:4_9,Kka2,kka2_1:4,P00552,1.09058,NO,9,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.079,-4.697,2.618,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.168804,0.00273264,1.09058 PSD95pdz3_E352K,PSD95pdz3_352,PSD95pdz3,PSD95pdz3,P31016,1.09058,NO,352,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.587,-2.94,1.353,5.49659,,,,,24.2,2.525,,86.88,OAH,-1.314,0.0758425,0.000892231,1.09058 kka2_1:2_D227E,kka2_1:2_227,Kka2,kka2_1:2,P00552,1.0906,NO,227,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.758,-3.138,1.38,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.295029,0.00745029,1.0906 kka2_1:4_D134H,kka2_1:4_134,Kka2,kka2_1:4,P00552,1.09062,NO,134,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.969,-4.532,3.563,,0.421,B,B,0.75,0.31,0.733,,49.62,HAB,-1.057,0.168804,0.00270812,1.09062 PSD95pdz3_S320T,PSD95pdz3_320,PSD95pdz3,PSD95pdz3,P31016,1.09067,NO,320,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.519,-2.653,1.134,5.81757,,,,,21.4517,,,,OPP,-1.306,0.0758425,0.00108158,1.09067 kka2_1:2_D134N,kka2_1:2_134,Kka2,kka2_1:2,P00552,1.09075,NO,134,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.969,-2.658,1.689,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.295029,0.00270812,1.09075 beta-lactamase_0_I206R,beta-lactamase_0_206,TEM-1,beta-lactamase_0,P62593,1.09083,NO,206,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-2.429,-3.125,0.696,,0.173,H,A,0.48,-0.34,3.411,,77.62,HHA,-1.805,0.0500837,0.00528934,1.09083 beta-lactamase_0_Q267M,beta-lactamase_0_267,TEM-1,beta-lactamase_0,P62593,1.09083,NO,267,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.0500837,0.0102128,1.09083 kka2_1:8_K175N,kka2_1:8_175,Kka2,kka2_1:8,P00552,1.09085,NO,175,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-2.897,-4.012,1.115,,0.579,H,A,2.34,0.51,15.316,15.316,71.59,HBH,-1.82333,0.100394,0.00693093,1.09085 kka2_1:8_K175N,kka2_1:8_175,Kka2,kka2_1:8,P00552,1.09085,NO,175,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-2.897,-4.012,1.115,,0.579,H,A,2.34,0.51,15.316,15.316,71.59,HBH,-1.82333,0.100394,0.00693093,1.09085 kka2_1:1_I2N,kka2_1:1_2,Kka2,kka2_1:1,P00552,1.09089,NO,2,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.787,-3.72,1.933,,,,,,,2.329,,71.59,HHA,-1.92433,0.520039,0.00246644,1.09089 kka2_1:8_K175S,kka2_1:8_175,Kka2,kka2_1:8,P00552,1.09089,NO,175,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-2.897,-3.083,0.186,,0.579,H,A,2.34,0.51,15.316,15.316,71.59,HBH,-1.82333,0.100394,0.00693093,1.09089 kka2_1:8_K175S,kka2_1:8_175,Kka2,kka2_1:8,P00552,1.09089,NO,175,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-2.897,-3.083,0.186,,0.579,H,A,2.34,0.51,15.316,15.316,71.59,HBH,-1.82333,0.100394,0.00693093,1.09089 beta-lactamase_0_A182R,beta-lactamase_0_182,TEM-1,beta-lactamase_0,P62593,1.0909,NO,182,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.777,-2.31,0.533,,0.136,H,A,0.46,-0.66,10.765,10.765,93.01,OHH,-1.27367,0.0500837,0.00559099,1.0909 kka2_1:8_R121L,kka2_1:8_121,Kka2,kka2_1:8,P00552,1.09091,NO,121,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.552,-2.477,0.925,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.100394,0.00523326,1.09091 kka2_1:8_R121L,kka2_1:8_121,Kka2,kka2_1:8,P00552,1.09091,NO,121,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.552,-2.477,0.925,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.100394,0.00523326,1.09091 beta-lactamase_0_Q267R,beta-lactamase_0_267,TEM-1,beta-lactamase_0,P62593,1.09092,NO,267,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.0500837,0.0102128,1.09092 PSD95pdz3_I314H,PSD95pdz3_314,PSD95pdz3,PSD95pdz3,P31016,1.09096,NO,314,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.628,-4.682,3.054,5.39919,,,,,15.7775,0.397,,81.35,BHH,-1.61167,0.0758425,0.0012606,1.09096 gb1_D273F,gb1_273,gb1,gb1,P06654,1.09097,NO,273,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.998,-4.208,2.21,,,,,,,3.514,3.514,37.28,AAH,-1.72767,0.177985,0.00318903,1.09097 beta-lactamase_0_D36W,beta-lactamase_0_36,TEM-1,beta-lactamase_0,P62593,1.09099,NO,36,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.732,-5.422,2.69,,0.555,H,A,0.75,1.17,13.689,13.689,77.62,AAP,-1.91167,0.0500837,0.00476483,1.09099 kka2_1:8_T73L,kka2_1:8_73,Kka2,kka2_1:8,P00552,1.091,NO,73,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.51,-2.574,0.064,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.100394,0.00628605,1.091 kka2_1:8_T73L,kka2_1:8_73,Kka2,kka2_1:8,P00552,1.091,NO,73,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.51,-2.574,0.064,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.100394,0.00628605,1.091 kka2_1:4_L53H,kka2_1:4_53,Kka2,kka2_1:4,P00552,1.09102,NO,53,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-2.681,-4.842,2.161,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.168804,0.00671168,1.09102 kka2_1:8_A137N,kka2_1:8_137,Kka2,kka2_1:8,P00552,1.09102,NO,137,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.156,-4.15,1.994,,0.029,H,A,1.04,0.34,2.886,,63.26,PHB,-2.559,0.100394,0.00515054,1.09102 kka2_1:8_A137N,kka2_1:8_137,Kka2,kka2_1:8,P00552,1.09102,NO,137,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.156,-4.15,1.994,,0.029,H,A,1.04,0.34,2.886,,63.26,PHB,-2.559,0.100394,0.00515054,1.09102 kka2_1:8_M178L,kka2_1:8_178,Kka2,kka2_1:8,P00552,1.09102,NO,178,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-3.206,-2.71,-0.496,,0.554,,b,1.59,0.68,13.268,13.268,71.59,BHO,-2.154,0.100394,0.00717253,1.09102 kka2_1:8_M178L,kka2_1:8_178,Kka2,kka2_1:8,P00552,1.09102,NO,178,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-3.206,-2.71,-0.496,,0.554,,b,1.59,0.68,13.268,13.268,71.59,BHO,-2.154,0.100394,0.00717253,1.09102 beta-lactamase_0_A182C,beta-lactamase_0_182,TEM-1,beta-lactamase_0,P62593,1.09106,NO,182,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.777,-5.025,3.248,,0.136,H,A,0.46,-0.66,10.765,10.765,93.01,OHH,-1.27367,0.0500837,0.00559099,1.09106 beta-lactamase_0_V101S,beta-lactamase_0_101,TEM-1,beta-lactamase_0,P62593,1.09107,NO,101,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.295,-3.65,2.355,,0.342,,B,0.44,0,1.61,,73.08,HHA,-1.54367,0.0500837,0.00374492,1.09107 kka2_1:8_D180N,kka2_1:8_180,Kka2,kka2_1:8,P00552,1.09109,NO,180,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.416,-3.09,0.674,,1.03,S,a,0.75,1.5,14.668,14.668,71.59,OAO,-2.02933,0.100394,0.00756412,1.09109 kka2_1:8_D180N,kka2_1:8_180,Kka2,kka2_1:8,P00552,1.09109,NO,180,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.416,-3.09,0.674,,1.03,S,a,0.75,1.5,14.668,14.668,71.59,OAO,-2.02933,0.100394,0.00756412,1.09109 kka2_1:8_K138L,kka2_1:8_138,Kka2,kka2_1:8,P00552,1.09112,NO,138,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-2.5,-3.647,1.147,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.100394,0.00628542,1.09112 kka2_1:8_K138L,kka2_1:8_138,Kka2,kka2_1:8,P00552,1.09112,NO,138,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-2.5,-3.647,1.147,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.100394,0.00628542,1.09112 kka2_1:2_E230Q,kka2_1:2_230,Kka2,kka2_1:2,P00552,1.09113,NO,230,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.672,-4.02,1.348,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.295029,0.00920051,1.09113 kka2_1:8_P179M,kka2_1:8_179,Kka2,kka2_1:8,P00552,1.09114,NO,179,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.974,-4.581,3.607,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.100394,0.00298346,1.09114 kka2_1:8_P179M,kka2_1:8_179,Kka2,kka2_1:8,P00552,1.09114,NO,179,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.974,-4.581,3.607,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.100394,0.00298346,1.09114 gb1_T277I,gb1_277,gb1,gb1,P06654,1.09115,NO,277,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.771,-3.367,1.596,,,,,,,0.824,,35.71,BPH,-1.54833,0.177985,0.00348258,1.09115 PSD95pdz3_E334M,PSD95pdz3_334,PSD95pdz3,PSD95pdz3,P31016,1.09119,NO,334,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.404,-4.387,2.983,5.60175,,,,,53.09,,,,OAO,-1.14,0.0758425,0.000912998,1.09119 kka2_1:8_R18M,kka2_1:8_18,Kka2,kka2_1:8,P00552,1.09132,NO,18,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.055,-3.102,1.047,,0.474,T,A,1.2,0.54,19.629,19.629,71.59,ABH,-1.821,0.100394,0.00724065,1.09132 kka2_1:8_R18M,kka2_1:8_18,Kka2,kka2_1:8,P00552,1.09132,NO,18,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.055,-3.102,1.047,,0.474,T,A,1.2,0.54,19.629,19.629,71.59,ABH,-1.821,0.100394,0.00724065,1.09132 beta-lactamase_0_A230G,beta-lactamase_0_230,TEM-1,beta-lactamase_0,P62593,1.09143,NO,230,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.154,-1.479,0.325,,0.01,E,B,0.46,-1.17,2.179,,50,HHA,-1.079,0.0500837,0.00516841,1.09143 kka2_1:4_I254S,kka2_1:4_254,Kka2,kka2_1:4,P00552,1.09144,NO,254,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.933,-3.691,1.758,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.168804,0.0132375,1.09144 beta-lactamase_0_R118E,beta-lactamase_0_118,TEM-1,beta-lactamase_0,P62593,1.09149,NO,118,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.413,-2.454,0.041,,0.457,H,A,1.2,1.39,3.961,,77.62,HBA,-1.785,0.0500837,0.00538794,1.09149 beta-lactamase_0_N173W,beta-lactamase_0_173,TEM-1,beta-lactamase_0,P62593,1.09151,NO,173,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-2.663,-5.303,2.64,,1.044,T,l,0.61,1.25,1.133,,77.62,OPA,-1.46633,0.0500837,0.0033769,1.09151 kka2_1:4_D238G,kka2_1:4_238,Kka2,kka2_1:4,P00552,1.09153,NO,238,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.83,-2.923,0.093,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.168804,0.0113863,1.09153 beta-lactamase_0_W163T,beta-lactamase_0_163,TEM-1,beta-lactamase_0,P62593,1.09154,NO,163,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-1.843,-2.765,0.922,,0.467,,B,0.47,-0.5,13.843,13.843,63.99,BHA,-1.269,0.0500837,0.00418955,1.09154 PSD95pdz3_Q391N,PSD95pdz3_391,PSD95pdz3,PSD95pdz3,P31016,1.09157,NO,391,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-1.699,-3.13,1.431,5.50275,,,,,12.6589,,,,HPH,-1.481,0.0758425,0.000990786,1.09157 kka2_1:4_A79Q,kka2_1:4_79,Kka2,kka2_1:4,P00552,1.09158,NO,79,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.368,-2.757,0.389,,0.563,.,B,0.46,-0.43,2.291,,71.59,HHH,-1.752,0.168804,0.00664821,1.09158 kka2_1:8_Q42T,kka2_1:8_42,Kka2,kka2_1:8,P00552,1.0916,NO,42,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.907,-2.915,0.008,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.100394,0.00679212,1.0916 kka2_1:8_Q42T,kka2_1:8_42,Kka2,kka2_1:8,P00552,1.0916,NO,42,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.907,-2.915,0.008,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.100394,0.00679212,1.0916 kka2_1:2_D250N,kka2_1:2_250,Kka2,kka2_1:2,P00552,1.09163,NO,250,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.015,-2.686,1.671,,0.274,.,b,0.75,-0.46,3.796,,51.89,OAP,-1.83933,0.295029,0.0177103,1.09163 PSD95pdz3_I338C,PSD95pdz3_338,PSD95pdz3,PSD95pdz3,P31016,1.09163,NO,338,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.63,-4.319,2.689,5.45113,,,,,13.0087,,,,HHP,-1.55767,0.0758425,0.000862587,1.09163 beta-lactamase_0_R273L,beta-lactamase_0_273,TEM-1,beta-lactamase_0,P62593,1.09164,NO,273,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.314,-3.556,1.242,,0.564,H,A,1.2,1.57,20.248,20.248,73.78,ABP,-1.841,0.0500837,0.0077952,1.09164 WW_domain_D170F,WW_domain_170,Yap65,WW_domain,P46937,1.09171,NO,170,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.213,-4.132,2.919,,,,,,,0.399,,15.87,OAH,-1.38,0.153962,0.00123319,1.09171 kka2_1:8_E169A,kka2_1:8_169,Kka2,kka2_1:8,P00552,1.09173,NO,169,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.996,-2.303,0.307,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.100394,0.00730086,1.09173 kka2_1:8_E169A,kka2_1:8_169,Kka2,kka2_1:8,P00552,1.09173,NO,169,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.996,-2.303,0.307,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.100394,0.00730086,1.09173 PSD95pdz3_V365Y,PSD95pdz3_365,PSD95pdz3,PSD95pdz3,P31016,1.09175,NO,365,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.592,-3.798,2.206,5.03791,,,,,18.9657,2.364,,81.35,OHA,-1.288,0.0758425,0.000649764,1.09175 kka2_1:1_G6R,kka2_1:1_6,Kka2,kka2_1:1,P00552,1.09177,NO,6,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.685,-3.575,1.89,,,,,,,1.292,,71.59,AOH,-1.639,0.520039,0.00204693,1.09177 kka2_1:4_E149I,kka2_1:4_149,Kka2,kka2_1:4,P00552,1.09178,NO,149,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.994,-3.262,1.268,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.168804,0.00803343,1.09178 PSD95pdz3_D366S,PSD95pdz3_366,PSD95pdz3,PSD95pdz3,P31016,1.09179,NO,366,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.264,-2.842,1.578,5.55684,,,,,20.2375,,,,HAH,-1.401,0.0758425,0.000481272,1.09179 PSD95pdz3_S320M,PSD95pdz3_320,PSD95pdz3,PSD95pdz3,P31016,1.09179,NO,320,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.519,-4.162,2.643,5.81757,,,,,21.4517,,,,OPP,-1.306,0.0758425,0.00108158,1.09179 kka2_1:2_P249L,kka2_1:2_249,Kka2,kka2_1:2,P00552,1.0918,NO,249,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.867,-2.363,0.496,,0.406,.,B,0.52,-0.01,0.76,,92.05,HOA,-1.66867,0.295029,0.011045,1.0918 kka2_1:8_A79Q,kka2_1:8_79,Kka2,kka2_1:8,P00552,1.09183,NO,79,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.368,-2.757,0.389,,0.563,.,B,0.46,-0.43,,,71.59,HHH,-1.752,0.100394,0.00664821,1.09183 kka2_1:8_A79Q,kka2_1:8_79,Kka2,kka2_1:8,P00552,1.09183,NO,79,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.368,-2.757,0.389,,0.563,.,B,0.46,-0.43,,,71.59,HHH,-1.752,0.100394,0.00664821,1.09183 kka2_1:8_V198A,kka2_1:8_198,Kka2,kka2_1:8,P00552,1.09184,NO,198,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.719,-1.379,-0.34,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.100394,0.00835002,1.09184 kka2_1:8_V198A,kka2_1:8_198,Kka2,kka2_1:8,P00552,1.09184,NO,198,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.719,-1.379,-0.34,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.100394,0.00835002,1.09184 beta-lactamase_0_H94Q,beta-lactamase_0_94,TEM-1,beta-lactamase_0,P62593,1.09188,NO,94,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-2.5,-3.155,0.655,,0.776,,B,0.17,1.24,1.176,,77.62,HBH,-1.872,0.0500837,0.00389226,1.09188 kka2_1:8_S68R,kka2_1:8_68,Kka2,kka2_1:8,P00552,1.09188,NO,68,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.623,-1.749,-0.874,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.100394,0.00608265,1.09188 kka2_1:8_S68R,kka2_1:8_68,Kka2,kka2_1:8,P00552,1.09188,NO,68,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.623,-1.749,-0.874,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.100394,0.00608265,1.09188 kka2_1:4_D90E,kka2_1:4_90,Kka2,kka2_1:4,P00552,1.09198,NO,90,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.459,-2.578,0.119,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.168804,0.00583842,1.09198 kka2_1:8_G21L,kka2_1:8_21,Kka2,kka2_1:8,P00552,1.09201,NO,21,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.368,-3.794,2.426,,0.586,T,l,0.29,-0.75,4.889,,71.59,HOH,-2.10167,0.100394,0.00709648,1.09201 kka2_1:8_G21L,kka2_1:8_21,Kka2,kka2_1:8,P00552,1.09201,NO,21,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.368,-3.794,2.426,,0.586,T,l,0.29,-0.75,4.889,,71.59,HOH,-2.10167,0.100394,0.00709648,1.09201 beta-lactamase_0_A235W,beta-lactamase_0_235,TEM-1,beta-lactamase_0,P62593,1.09206,NO,235,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.266,-5.379,4.113,,0.32,E,B,0.46,-0.86,2.261,,50,OHO,-0.89,0.0500837,0.00493474,1.09206 kka2_1:1_D5F,kka2_1:1_5,Kka2,kka2_1:1,P00552,1.09209,NO,5,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.306,-4.103,2.797,,,,,,,0.895,,71.59,PAO,-1.784,0.520039,0.00222864,1.09209 kka2_1:4_T73W,kka2_1:4_73,Kka2,kka2_1:4,P00552,1.09213,NO,73,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.51,-5.397,2.887,,0.309,H,A,0.22,0.35,1.53,,56.06,PPO,-2.02333,0.168804,0.00628605,1.09213 beta-lactamase_0_Y44P,beta-lactamase_0_44,TEM-1,beta-lactamase_0,P62593,1.09215,NO,44,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-2.547,-4.12,1.573,,,E,B,0.21,-0.45,1.751,,73.78,OHH,-1.86267,0.0500837,0.00426364,1.09215 kka2_1:8_S114R,kka2_1:8_114,Kka2,kka2_1:8,P00552,1.09222,NO,114,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.527,-2.846,0.319,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.100394,0.00705262,1.09222 kka2_1:8_S114R,kka2_1:8_114,Kka2,kka2_1:8,P00552,1.09222,NO,114,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.527,-2.846,0.319,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.100394,0.00705262,1.09222 kka2_1:8_V83Y,kka2_1:8_83,Kka2,kka2_1:8,P00552,1.09222,NO,83,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-2.567,-3.301,0.734,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.100394,0.00650486,1.09222 kka2_1:8_V83Y,kka2_1:8_83,Kka2,kka2_1:8,P00552,1.09222,NO,83,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-2.567,-3.301,0.734,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.100394,0.00650486,1.09222 beta-lactamase_0_R118D,beta-lactamase_0_118,TEM-1,beta-lactamase_0,P62593,1.09231,NO,118,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.413,-2.866,0.453,,0.457,H,A,1.2,1.39,3.961,,77.62,HBA,-1.785,0.0500837,0.00538794,1.09231 beta-lactamase_0_R92A,beta-lactamase_0_92,TEM-1,beta-lactamase_0,P62593,1.09239,NO,92,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.718,-2.705,0.987,,0.479,E,B,1.2,1.36,2.331,,65.38,BBH,-1.50367,0.0500837,0.00429626,1.09239 kka2_1:8_T73W,kka2_1:8_73,Kka2,kka2_1:8,P00552,1.09245,NO,73,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.51,-5.397,2.887,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.100394,0.00628605,1.09245 kka2_1:8_T73W,kka2_1:8_73,Kka2,kka2_1:8,P00552,1.09245,NO,73,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.51,-5.397,2.887,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.100394,0.00628605,1.09245 kka2_1:4_E199F,kka2_1:4_199,Kka2,kka2_1:4,P00552,1.09247,NO,199,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.234,-4.372,2.138,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.168804,0.00854122,1.09247 kka2_1:8_E235W,kka2_1:8_235,Kka2,kka2_1:8,P00552,1.09258,NO,235,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.955,-5.585,3.63,,0.631,H,A,1.52,0.12,,,65.53,OAH,-2.07267,0.100394,0.0102806,1.09258 kka2_1:8_E235W,kka2_1:8_235,Kka2,kka2_1:8,P00552,1.09258,NO,235,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.955,-5.585,3.63,,0.631,H,A,1.52,0.12,,,65.53,OAH,-2.07267,0.100394,0.0102806,1.09258 beta-lactamase_39_V106H,beta-lactamase_39_106,TEM-1,beta-lactamase_39,P62593,1.09263,NO,106,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.218,-4.937,3.719,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.0495842,0.00304168,1.09263 kka2_1:8_T125M,kka2_1:8_125,Kka2,kka2_1:8,P00552,1.09266,NO,125,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.622,-4.759,2.137,,0.791,T,A,0.22,0.33,2.675,,92.05,BPH,-1.56933,0.100394,0.00821755,1.09266 kka2_1:8_T125M,kka2_1:8_125,Kka2,kka2_1:8,P00552,1.09266,NO,125,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.622,-4.759,2.137,,0.791,T,A,0.22,0.33,2.675,,92.05,BPH,-1.56933,0.100394,0.00821755,1.09266 kka2_1:8_E111N,kka2_1:8_111,Kka2,kka2_1:8,P00552,1.09268,NO,111,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.28,-3.19,0.91,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.100394,0.00746789,1.09268 kka2_1:8_E111N,kka2_1:8_111,Kka2,kka2_1:8,P00552,1.09268,NO,111,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.28,-3.19,0.91,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.100394,0.00746789,1.09268 gb1_T279G,gb1_279,gb1,gb1,P06654,1.09269,NO,279,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.32,-3.308,1.988,,,,,,,0.529,,35.71,HPH,-1.50067,0.177985,0.00421454,1.09269 beta-lactamase_0_L73M,beta-lactamase_0_73,TEM-1,beta-lactamase_0,P62593,1.09271,NO,73,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.507,-2.898,1.391,,,H,A,0.55,-0.64,0.877,,67.83,HHH,-1.487,0.0500837,0.00488983,1.09271 kka2_1:2_V46N,kka2_1:2_46,Kka2,kka2_1:2,P00552,1.09276,NO,46,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-2.62,-3.225,0.605,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.295029,0.00631301,1.09276 kka2_1:8_V75A,kka2_1:8_75,Kka2,kka2_1:8,P00552,1.09279,NO,75,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-2.06,-3.254,1.194,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.100394,0.00693733,1.09279 kka2_1:8_V75A,kka2_1:8_75,Kka2,kka2_1:8,P00552,1.09279,NO,75,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-2.06,-3.254,1.194,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.100394,0.00693733,1.09279 WW_domain_P172R,WW_domain_172,Yap65,WW_domain,P46937,1.09283,NO,172,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.035,-3.71,2.675,,,,,,,,,,HOH,-1.233,0.153962,0.000991485,1.09283 kka2_1:2_K175N,kka2_1:2_175,Kka2,kka2_1:2,P00552,1.09286,NO,175,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-2.897,-4.012,1.115,,0.579,H,A,1.3,0.51,15.629,15.629,71.59,HBH,-1.82333,0.295029,0.00693093,1.09286 kka2_1:8_V97M,kka2_1:8_97,Kka2,kka2_1:8,P00552,1.09289,NO,97,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.453,-2.867,1.414,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.100394,0.00737869,1.09289 kka2_1:8_V97M,kka2_1:8_97,Kka2,kka2_1:8,P00552,1.09289,NO,97,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.453,-2.867,1.414,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.100394,0.00737869,1.09289 kka2_1:2_L243M,kka2_1:2_243,Kka2,kka2_1:2,P00552,1.09293,NO,243,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-2.651,-4.688,2.037,,0.277,H,A,1.59,-0.67,13.165,13.165,92.05,HHH,-2.03767,0.295029,0.00884927,1.09293 WW_domain_V171E,WW_domain_171,Yap65,WW_domain,P46937,1.09296,NO,171,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.547,-3.584,2.037,,,,,,,3.459,,70.24,AHO,-1.265,0.153962,0.00184125,1.09296 kka2_1:8_Q155E,kka2_1:8_155,Kka2,kka2_1:8,P00552,1.09299,NO,155,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.606,-1.223,-1.383,,0.525,T,A,0.64,1.49,,,63.64,APA,-1.726,0.100394,0.00641853,1.09299 kka2_1:8_Q155E,kka2_1:8_155,Kka2,kka2_1:8,P00552,1.09299,NO,155,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.606,-1.223,-1.383,,0.525,T,A,0.64,1.49,,,63.64,APA,-1.726,0.100394,0.00641853,1.09299 PSD95pdz3_Q384F,PSD95pdz3_384,PSD95pdz3,PSD95pdz3,P31016,1.09299,NO,384,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-1.699,-3.974,2.275,5.49339,,,,,23.54,,,,OPP,-1.41333,0.0758425,0.000216736,1.09299 kka2_1:8_A56R,kka2_1:8_56,Kka2,kka2_1:8,P00552,1.09302,NO,56,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.083,-3.254,1.171,,0.796,T,A,0.46,1.39,10.511,,71.59,OHH,-1.86867,0.100394,0.00717715,1.09302 kka2_1:8_A56R,kka2_1:8_56,Kka2,kka2_1:8,P00552,1.09302,NO,56,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.083,-3.254,1.171,,0.796,T,A,0.46,1.39,10.511,,71.59,OHH,-1.86867,0.100394,0.00717715,1.09302 beta-lactamase_0_L150Y,beta-lactamase_0_150,TEM-1,beta-lactamase_0,P62593,1.09303,NO,150,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.326,-4.133,2.807,,,H,A,0.55,-0.2,2.128,,62.94,HHB,-1.86167,0.0500837,0.00463171,1.09303 kka2_1:2_Q136N,kka2_1:2_136,Kka2,kka2_1:2,P00552,1.09304,NO,136,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-3.021,-3.645,0.624,,0.331,,b,0.4,0.96,2.726,,92.05,BPH,-2.16933,0.295029,0.00624149,1.09304 kka2_1:2_R44S,kka2_1:2_44,Kka2,kka2_1:2,P00552,1.09304,NO,44,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.062,-2.625,0.563,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.295029,0.00745043,1.09304 WW_domain_Q200H,WW_domain_200,Yap65,WW_domain,P46937,1.09314,NO,200,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-1.599,-4.164,2.565,5.37476,,,,,,1.9,,70.04,HPA,-1.484,0.153962,0.00300397,1.09314 PSD95pdz3_I314G,PSD95pdz3_314,PSD95pdz3,PSD95pdz3,P31016,1.09318,NO,314,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.628,-3.489,1.861,5.39919,,,,,15.7775,0.397,,81.35,BHH,-1.61167,0.0758425,0.0012606,1.09318 kka2_1:8_P179C,kka2_1:8_179,Kka2,kka2_1:8,P00552,1.09323,NO,179,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.974,-5.011,4.037,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.100394,0.00298346,1.09323 kka2_1:8_P179C,kka2_1:8_179,Kka2,kka2_1:8,P00552,1.09323,NO,179,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.974,-5.011,4.037,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.100394,0.00298346,1.09323 beta-lactamase_0_V72T,beta-lactamase_0_72,TEM-1,beta-lactamase_0,P62593,1.09337,NO,72,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.658,-2.757,1.099,,,H,A,0.44,-1.03,2.964,,65.73,BHH,-1.32167,0.0500837,0.00501194,1.09337 kka2_1:8_G55H,kka2_1:8_55,Kka2,kka2_1:8,P00552,1.09349,NO,55,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.625,-2.922,1.297,,0.517,S,b,0.29,1.19,8.881,,63.64,POH,-2.05967,0.100394,0.00667877,1.09349 kka2_1:8_G55H,kka2_1:8_55,Kka2,kka2_1:8,P00552,1.09349,NO,55,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.625,-2.922,1.297,,0.517,S,b,0.29,1.19,8.881,,63.64,POH,-2.05967,0.100394,0.00667877,1.09349 beta-lactamase_0_T112G,beta-lactamase_0_112,TEM-1,beta-lactamase_0,P62593,1.09358,NO,112,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.186,-1.822,-0.364,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.0500837,0.00531334,1.09358 kka2_1:8_N200S,kka2_1:8_200,Kka2,kka2_1:8,P00552,1.09358,NO,200,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-2.446,-2.785,0.339,,0.756,T,L,0.43,-0.08,2.528,,64.39,APO,-2.08,0.100394,0.00838549,1.09358 kka2_1:8_N200S,kka2_1:8_200,Kka2,kka2_1:8,P00552,1.09358,NO,200,N,S,NS,Polar,Polar,5.47157,5.68,0.208425,46,132,105,-27,114.1,89,-25.1,-2.446,-2.785,0.339,,0.756,T,L,0.43,-0.08,2.528,,64.39,APO,-2.08,0.100394,0.00838549,1.09358 kka2_1:2_R145H,kka2_1:2_145,Kka2,kka2_1:2,P00552,1.09361,NO,145,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.804,-3.445,1.641,,0.346,H,A,1.2,1.23,7.961,,63.64,HBP,-1.88033,0.295029,0.00846663,1.09361 gb1_D273S,gb1_273,gb1,gb1,P06654,1.09369,NO,273,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.998,-2.296,0.298,,,,,,,3.514,3.514,37.28,AAH,-1.72767,0.177985,0.00318903,1.09369 beta-lactamase_0_Y103W,beta-lactamase_0_103,TEM-1,beta-lactamase_0,P62593,1.09372,NO,103,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-1.33,-2.453,1.123,,0.613,S,l,0.21,1.21,1.646,,63.29,AHP,-1.48767,0.0500837,0.00443048,1.09372 beta-lactamase_0_Q86G,beta-lactamase_0_86,TEM-1,beta-lactamase_0,P62593,1.09373,NO,86,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.4,-2.887,0.487,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.0500837,0.00450027,1.09373 kka2_1:2_Q163N,kka2_1:2_163,Kka2,kka2_1:2,P00552,1.09378,NO,163,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.162,-3.939,1.777,,0.58,T,B,0.64,1.85,3.888,,64.02,BPO,-1.78333,0.295029,0.00719507,1.09378 beta-lactamase_39_I171L,beta-lactamase_39_171,TEM-1,beta-lactamase_39,P62593,1.09379,NO,171,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-2.431,-1.98,-0.451,,0.361,,B,0.48,0.53,16.954,16.954,77.62,HHO,-1.55533,0.0495842,0.00623355,1.09379 PSD95pdz3_E334S,PSD95pdz3_334,PSD95pdz3,PSD95pdz3,P31016,1.09382,NO,334,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.404,-2.842,1.438,5.60175,,,,,53.09,,,,OAO,-1.14,0.0758425,0.000912998,1.09382 kka2_1:4_I2E,kka2_1:4_2,Kka2,kka2_1:4,P00552,1.09385,NO,2,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.787,-3.519,1.732,,,,,,,,,71.59,HHA,-1.92433,0.168804,0.00246644,1.09385 gb1_T251F,gb1_251,gb1,gb1,P06654,1.09386,NO,251,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.794,-3.945,2.151,,,,,,,3.514,3.514,37.28,HPH,-1.56067,0.177985,0.00232932,1.09386 kka2_1:8_D33Q,kka2_1:8_33,Kka2,kka2_1:8,P00552,1.09386,NO,33,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.186,-3.005,0.819,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.100394,0.00633568,1.09386 kka2_1:8_D33Q,kka2_1:8_33,Kka2,kka2_1:8,P00552,1.09386,NO,33,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.186,-3.005,0.819,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.100394,0.00633568,1.09386 PSD95pdz3_F337Y,PSD95pdz3_337,PSD95pdz3,PSD95pdz3,P31016,1.09386,NO,337,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.524,-2.719,1.195,5.22838,,,,,13.4936,,,,HHH,-1.59467,0.0758425,0.000875287,1.09386 kka2_1:8_D250H,kka2_1:8_250,Kka2,kka2_1:8,P00552,1.09392,NO,250,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.015,-4.493,3.478,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.100394,0.0177103,1.09392 kka2_1:8_D250H,kka2_1:8_250,Kka2,kka2_1:8,P00552,1.09392,NO,250,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.015,-4.493,3.478,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.100394,0.0177103,1.09392 beta-lactamase_0_H24V,beta-lactamase_0_24,TEM-1,beta-lactamase_0,P62593,1.09393,NO,24,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-2.481,-3.524,1.043,,,,,,,2.708,,93.01,OBO,-2.0035,0.0500837,0.00238894,1.09393 beta-lactamase_0_A246C,beta-lactamase_0_246,TEM-1,beta-lactamase_0,P62593,1.09395,NO,246,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.121,-3.242,1.121,,0.01,E,B,0.46,-1.01,1.201,,73.78,HHH,-1.55633,0.0500837,0.00569458,1.09395 beta-lactamase_0_V78C,beta-lactamase_0_78,TEM-1,beta-lactamase_0,P62593,1.09403,NO,78,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.459,-4.812,3.353,,,H,A,0.44,-0.47,16.615,16.615,63.64,HHH,-1.17833,0.0500837,0.00492501,1.09403 PSD95pdz3_I388F,PSD95pdz3_388,PSD95pdz3,PSD95pdz3,P31016,1.09403,NO,388,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.63,-3.299,1.669,5.17282,,,,,16.0025,,,,PHH,-1.54967,0.0758425,0.000151216,1.09403 beta-lactamase_0_E279I,beta-lactamase_0_279,TEM-1,beta-lactamase_0,P62593,1.09405,NO,279,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.0500837,0.0192826,1.09405 Pab1_A141C,Pab1_141,Pab1,Pab1,P04147,1.09407,NO,141,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.461,-4.457,2.996,,0.34,H,A,0.52,-0.27,2.15,,79.03,BHH,-1.19433,0.175299,0.00165974,1.09407 kka2_1:2_Q27S,kka2_1:2_27,Kka2,kka2_1:2,P00552,1.09408,NO,27,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-1.659,-3.464,1.805,,0.608,.,A,0.64,0.71,0.521,,65.53,PPP,-1.90733,0.295029,0.00595365,1.09408 kka2_1:4_R44Q,kka2_1:4_44,Kka2,kka2_1:4,P00552,1.09409,NO,44,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.062,-2.483,0.421,,0.487,S,B,1.2,-0.35,5.71,,71.59,OBO,-1.80767,0.168804,0.00745043,1.09409 kka2_1:4_T72L,kka2_1:4_72,Kka2,kka2_1:4,P00552,1.09411,NO,72,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.38,-3.619,1.239,,0.784,H,A,0.82,0.29,6.463,,65.53,HPP,-2.238,0.168804,0.00750756,1.09411 kka2_1:2_A25C,kka2_1:2_25,Kka2,kka2_1:2,P00552,1.09413,NO,25,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.496,-5.199,2.703,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.295029,0.00595636,1.09413 kka2_1:2_T51Q,kka2_1:2_51,Kka2,kka2_1:2,P00552,1.09413,NO,51,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.199,-3.313,1.114,,0.05,E,B,0.22,-0.05,13.165,13.165,63.64,BPA,-1.76767,0.295029,0.00628861,1.09413 kka2_1:8_L19C,kka2_1:8_19,Kka2,kka2_1:8,P00552,1.09413,NO,19,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.254,-4.888,3.634,,0.08,T,A,1.59,-0.26,2.044,,65.53,BHH,-2.221,0.100394,0.00620703,1.09413 kka2_1:8_L19C,kka2_1:8_19,Kka2,kka2_1:8,P00552,1.09413,NO,19,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.254,-4.888,3.634,,0.08,T,A,1.59,-0.26,2.044,,65.53,BHH,-2.221,0.100394,0.00620703,1.09413 kka2_1:4_Q163K,kka2_1:4_163,Kka2,kka2_1:4,P00552,1.09415,NO,163,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.162,-2.924,0.762,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.168804,0.00719507,1.09415 kka2_1:1_M120L,kka2_1:1_120,Kka2,kka2_1:1,P00552,1.09418,NO,120,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-3.877,-0.807,-3.07,,,H,A,0.55,-0.42,2.259,,92.05,HHB,-2.16733,0.520039,0.00265808,1.09418 PSD95pdz3_H317D,PSD95pdz3_317,PSD95pdz3,PSD95pdz3,P31016,1.09419,NO,317,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-1.627,-3.15,1.523,6.19713,,,,,25.885,,,,HBB,-1.613,0.0758425,0.00111619,1.09419 beta-lactamase_0_R41E,beta-lactamase_0_41,TEM-1,beta-lactamase_0,P62593,1.09424,NO,41,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-0.942,-3.241,2.299,,0.321,E,B,1.2,-0.07,2.68,,65.03,HBH,-1.30267,0.0500837,0.00123327,1.09424 beta-lactamase_0_A84F,beta-lactamase_0_84,TEM-1,beta-lactamase_0,P62593,1.09425,NO,84,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.651,-4.366,2.715,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.0500837,0.00503822,1.09425 kka2_1:8_L107Y,kka2_1:8_107,Kka2,kka2_1:8,P00552,1.09432,NO,107,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.238,-4.146,2.908,,0.197,.,B,0.55,-1.1,4.478,,71.59,BHH,-2.143,0.100394,0.00561937,1.09432 kka2_1:8_L107Y,kka2_1:8_107,Kka2,kka2_1:8,P00552,1.09432,NO,107,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.238,-4.146,2.908,,0.197,.,B,0.55,-1.1,4.478,,71.59,BHH,-2.143,0.100394,0.00561937,1.09432 beta-lactamase_0_K190F,beta-lactamase_0_190,TEM-1,beta-lactamase_0,P62593,1.09435,NO,190,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.994,-4.396,2.402,,0.371,H,A,2.34,0.16,16.606,16.606,77.62,BBH,-1.64167,0.0500837,0.00574527,1.09435 kka2_1:1_S251K,kka2_1:1_251,Kka2,kka2_1:1,P00552,1.09436,NO,251,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.636,-3.007,0.371,,0.712,H,A,0.27,-0.25,1.356,,71.59,APP,-2.09367,0.520039,0.0138916,1.09436 kka2_1:8_R143Y,kka2_1:8_143,Kka2,kka2_1:8,P00552,1.09438,NO,143,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.525,-4.353,1.828,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.100394,0.00662247,1.09438 kka2_1:8_R143Y,kka2_1:8_143,Kka2,kka2_1:8,P00552,1.09438,NO,143,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.525,-4.353,1.828,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.100394,0.00662247,1.09438 beta-lactamase_0_T116M,beta-lactamase_0_116,TEM-1,beta-lactamase_0,P62593,1.09439,NO,116,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.28,-4.634,3.354,,0.115,E,B,0.22,-0.12,1.356,,67.48,HPH,-1.39967,0.0500837,0.00336175,1.09439 gb1_T277V,gb1_277,gb1,gb1,P06654,1.0944,NO,277,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.771,-2.285,0.514,,,,,,,0.824,,35.71,BPH,-1.54833,0.177985,0.00348258,1.0944 kka2_1:4_G181I,kka2_1:4_181,Kka2,kka2_1:4,P00552,1.09442,NO,181,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-2.698,-3.104,0.406,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.168804,0.00728319,1.09442 kka2_1:2_I141T,kka2_1:2_141,Kka2,kka2_1:2,P00552,1.09443,NO,141,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.495,-3.551,2.056,,0.068,H,A,0.48,-0.01,0.819,,92.05,BHA,-1.689,0.295029,0.00744745,1.09443 kka2_1:2_A110Q,kka2_1:2_110,Kka2,kka2_1:2,P00552,1.09453,NO,110,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.064,-2.476,0.412,,0.175,H,A,0.46,-1.19,23.237,23.237,71.59,OHA,-1.91867,0.295029,0.00759851,1.09453 PSD95pdz3_G364W,PSD95pdz3_364,PSD95pdz3,PSD95pdz3,P31016,1.09453,NO,364,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.008,-4.779,3.771,5.53299,,,,,21.28,,,,POH,-1.33667,0.0758425,0.00050942,1.09453 kka2_1:8_A150Q,kka2_1:8_150,Kka2,kka2_1:8,P00552,1.09455,NO,150,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.949,-2.897,1.948,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.100394,0.0045009,1.09455 kka2_1:8_A150Q,kka2_1:8_150,Kka2,kka2_1:8,P00552,1.09455,NO,150,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.949,-2.897,1.948,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.100394,0.0045009,1.09455 beta-lactamase_0_A247P,beta-lactamase_0_247,TEM-1,beta-lactamase_0,P62593,1.09458,NO,247,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.0500837,0.00611275,1.09458 kka2_1:2_S68T,kka2_1:2_68,Kka2,kka2_1:2,P00552,1.09466,NO,68,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.623,-3.655,1.032,,0.48,H,A,0.27,-0.1,2.655,,71.59,HPH,-1.40767,0.295029,0.00608265,1.09466 PSD95pdz3_V365F,PSD95pdz3_365,PSD95pdz3,PSD95pdz3,P31016,1.09471,NO,365,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.592,-3.703,2.111,5.03791,,,,,18.9657,2.364,,81.35,OHA,-1.288,0.0758425,0.000649764,1.09471 kka2_1:4_T130N,kka2_1:4_130,Kka2,kka2_1:4,P00552,1.09472,NO,130,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.392,-2.756,0.364,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.168804,0.00804204,1.09472 kka2_1:8_E96A,kka2_1:8_96,Kka2,kka2_1:8,P00552,1.09473,NO,96,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.573,-1.097,-1.476,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.100394,0.00369441,1.09473 kka2_1:8_E96A,kka2_1:8_96,Kka2,kka2_1:8,P00552,1.09473,NO,96,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.573,-1.097,-1.476,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.100394,0.00369441,1.09473 kka2_1:8_G55R,kka2_1:8_55,Kka2,kka2_1:8,P00552,1.09479,NO,55,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.625,-4.045,2.42,,0.517,S,b,0.29,1.19,8.881,,63.64,POH,-2.05967,0.100394,0.00667877,1.09479 kka2_1:8_G55R,kka2_1:8_55,Kka2,kka2_1:8,P00552,1.09479,NO,55,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.625,-4.045,2.42,,0.517,S,b,0.29,1.19,8.881,,63.64,POH,-2.05967,0.100394,0.00667877,1.09479 kka2_1:8_A79I,kka2_1:8_79,Kka2,kka2_1:8,P00552,1.0948,NO,79,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.368,-3.11,0.742,,0.563,.,B,0.46,-0.43,,,71.59,HHH,-1.752,0.100394,0.00664821,1.0948 kka2_1:8_A79I,kka2_1:8_79,Kka2,kka2_1:8,P00552,1.0948,NO,79,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.368,-3.11,0.742,,0.563,.,B,0.46,-0.43,,,71.59,HHH,-1.752,0.100394,0.00664821,1.0948 kka2_1:8_M148A,kka2_1:8_148,Kka2,kka2_1:8,P00552,1.09482,NO,148,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.847,-2.283,0.436,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.100394,0.00982664,1.09482 kka2_1:8_M148A,kka2_1:8_148,Kka2,kka2_1:8,P00552,1.09482,NO,148,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.847,-2.283,0.436,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.100394,0.00982664,1.09482 kka2_1:4_L103R,kka2_1:4_103,Kka2,kka2_1:4,P00552,1.09488,NO,103,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-2.362,-3.979,1.617,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.168804,0.00574792,1.09488 kka2_1:8_E96N,kka2_1:8_96,Kka2,kka2_1:8,P00552,1.09489,NO,96,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.573,-3.878,1.305,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.100394,0.00369441,1.09489 kka2_1:8_E96N,kka2_1:8_96,Kka2,kka2_1:8,P00552,1.09489,NO,96,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.573,-3.878,1.305,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.100394,0.00369441,1.09489 beta-lactamase_0_T116H,beta-lactamase_0_116,TEM-1,beta-lactamase_0,P62593,1.0949,NO,116,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.28,-4.615,3.335,,0.115,E,B,0.22,-0.12,1.356,,67.48,HPH,-1.39967,0.0500837,0.00336175,1.0949 kka2_1:8_D62G,kka2_1:8_62,Kka2,kka2_1:8,P00552,1.09492,NO,62,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.591,-1.697,0.106,,0.262,H,A,0.29,0.08,5.58,,64.39,PAA,-1.77833,0.100394,0.00744243,1.09492 kka2_1:8_D62G,kka2_1:8_62,Kka2,kka2_1:8,P00552,1.09492,NO,62,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.591,-1.697,0.106,,0.262,H,A,0.29,0.08,5.58,,64.39,PAA,-1.77833,0.100394,0.00744243,1.09492 kka2_1:2_A9R,kka2_1:2_9,Kka2,kka2_1:2,P00552,1.09494,NO,9,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.079,-3.835,1.756,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.295029,0.00273264,1.09494 beta-lactamase_L19W,beta-lactamase_19,TEM-1,beta-lactamase,P62593,1.09495,NO,19,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.682,-5.056,3.374,,,,,,,4.261,,93.01,OHO,-1.894,0.221079,0.00215974,1.09495 kka2_1:8_I254N,kka2_1:8_254,Kka2,kka2_1:8,P00552,1.09495,NO,254,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.933,-4.208,2.275,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.100394,0.0132375,1.09495 kka2_1:8_I254N,kka2_1:8_254,Kka2,kka2_1:8,P00552,1.09495,NO,254,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.933,-4.208,2.275,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.100394,0.0132375,1.09495 kka2_1:4_L107I,kka2_1:4_107,Kka2,kka2_1:4,P00552,1.09504,NO,107,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.238,-2.172,0.934,,0.197,.,B,0.55,-1.1,0.398,,71.59,BHH,-2.143,0.168804,0.00561937,1.09504 beta-lactamase_0_A247E,beta-lactamase_0_247,TEM-1,beta-lactamase_0,P62593,1.0951,NO,247,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.0500837,0.00611275,1.0951 kka2_1:8_P12E,kka2_1:8_12,Kka2,kka2_1:8,P00552,1.09516,NO,12,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.853,-3.478,2.625,,,.,B,0.52,1.25,2.41,,48.11,POH,-1.80767,0.100394,0.00500011,1.09516 kka2_1:8_P12E,kka2_1:8_12,Kka2,kka2_1:8,P00552,1.09516,NO,12,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.853,-3.478,2.625,,,.,B,0.52,1.25,2.41,,48.11,POH,-1.80767,0.100394,0.00500011,1.09516 kka2_1:4_D156H,kka2_1:4_156,Kka2,kka2_1:4,P00552,1.09529,NO,156,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.696,-4.723,3.027,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.168804,0.00926998,1.09529 kka2_1:4_G43P,kka2_1:4_43,Kka2,kka2_1:4,P00552,1.09531,NO,43,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.587,-4.038,2.451,,0.862,T,l,0.75,-0.67,2.247,,63.26,POB,-2.18533,0.168804,0.0071925,1.09531 kka2_1:8_L60C,kka2_1:8_60,Kka2,kka2_1:8,P00552,1.09534,NO,60,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.997,-4.773,3.776,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.100394,0.00262176,1.09534 kka2_1:8_L60C,kka2_1:8_60,Kka2,kka2_1:8,P00552,1.09534,NO,60,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.997,-4.773,3.776,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.100394,0.00262176,1.09534 gb1_Y271W,gb1_271,gb1,gb1,P06654,1.09538,NO,271,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-1.181,-3.974,2.793,,,,,,,,,,PHA,-1.92933,0.177985,0.00236544,1.09538 beta-lactamase_0_A170Q,beta-lactamase_0_170,TEM-1,beta-lactamase_0,P62593,1.09546,NO,170,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.237,-4.086,2.849,,0.126,,L,0.46,-0.35,2.427,,64.69,AHH,-1.63267,0.0500837,0.00431903,1.09546 beta-lactamase_0_L38H,beta-lactamase_0_38,TEM-1,beta-lactamase_0,P62593,1.09551,NO,38,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.343,-3.182,1.839,,0.088,H,A,0.55,0.2,13.556,13.556,64.34,PHO,-1.78033,0.0500837,0.00373244,1.09551 kka2_1:4_A79V,kka2_1:4_79,Kka2,kka2_1:4,P00552,1.09552,NO,79,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.368,-2.938,0.57,,0.563,.,B,0.46,-0.43,2.291,,71.59,HHH,-1.752,0.168804,0.00664821,1.09552 kka2_1:2_T130N,kka2_1:2_130,Kka2,kka2_1:2,P00552,1.09557,NO,130,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.392,-2.756,0.364,,0.561,G,A,0.22,0.77,0.5,,92.05,HPO,-1.62633,0.295029,0.00804204,1.09557 beta-lactamase_0_M270S,beta-lactamase_0_270,TEM-1,beta-lactamase_0,P62593,1.0956,NO,270,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.0500837,0.00767762,1.0956 kka2_1:8_G74M,kka2_1:8_74,Kka2,kka2_1:8,P00552,1.09571,NO,74,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.18,-4.972,3.792,,0.621,T,l,0.29,0.2,2.014,,64.39,POH,-1.91667,0.100394,0.00587035,1.09571 kka2_1:8_G74M,kka2_1:8_74,Kka2,kka2_1:8,P00552,1.09571,NO,74,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.18,-4.972,3.792,,0.621,T,l,0.29,0.2,2.014,,64.39,POH,-1.91667,0.100394,0.00587035,1.09571 kka2_1:2_V84H,kka2_1:2_84,Kka2,kka2_1:2,P00552,1.09572,NO,84,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-2.279,-3.484,1.205,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.295029,0.00724019,1.09572 beta-lactamase_0_W163Y,beta-lactamase_0_163,TEM-1,beta-lactamase_0,P62593,1.09573,NO,163,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-1.843,-3.906,2.063,,0.467,,B,0.47,-0.5,13.843,13.843,63.99,BHA,-1.269,0.0500837,0.00418955,1.09573 kka2_1:8_G55S,kka2_1:8_55,Kka2,kka2_1:8,P00552,1.09573,NO,55,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.625,-2.154,0.529,,0.517,S,b,0.29,1.19,8.881,,63.64,POH,-2.05967,0.100394,0.00667877,1.09573 kka2_1:8_G55S,kka2_1:8_55,Kka2,kka2_1:8,P00552,1.09573,NO,55,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.625,-2.154,0.529,,0.517,S,b,0.29,1.19,8.881,,63.64,POH,-2.05967,0.100394,0.00667877,1.09573 kka2_1:8_M178E,kka2_1:8_178,Kka2,kka2_1:8,P00552,1.09576,NO,178,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-3.206,-3.572,0.366,,0.554,,b,1.59,0.68,13.268,13.268,71.59,BHO,-2.154,0.100394,0.00717253,1.09576 kka2_1:8_M178E,kka2_1:8_178,Kka2,kka2_1:8,P00552,1.09576,NO,178,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-3.206,-3.572,0.366,,0.554,,b,1.59,0.68,13.268,13.268,71.59,BHO,-2.154,0.100394,0.00717253,1.09576 kka2_1:2_A56S,kka2_1:2_56,Kka2,kka2_1:2,P00552,1.09582,NO,56,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.083,-2.605,0.522,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.295029,0.00717715,1.09582 kka2_1:2_V49I,kka2_1:2_49,Kka2,kka2_1:2,P00552,1.09583,NO,49,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.614,-2.255,0.641,,,E,B,0.44,-0.77,1.233,,64.39,HHB,-1.3,0.295029,0.00615685,1.09583 kka2_1:4_T73S,kka2_1:4_73,Kka2,kka2_1:4,P00552,1.09583,NO,73,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.51,-2.503,-0.007,,0.309,H,A,0.22,0.35,1.53,,56.06,PPO,-2.02333,0.168804,0.00628605,1.09583 beta-lactamase_0_E61Y,beta-lactamase_0_61,TEM-1,beta-lactamase_0,P62593,1.09589,NO,61,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.115,-4.403,2.288,,0.775,T,a,1.04,1.29,34.763,34.763,77.62,OAA,-1.92567,0.0500837,0.00440955,1.09589 kka2_1:1_Q252D,kka2_1:1_252,Kka2,kka2_1:1,P00552,1.0959,NO,252,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.63,-2.481,-0.149,,0.906,H,A,0.64,0.35,1.369,,92.05,PPB,-2.20733,0.520039,0.0121001,1.0959 kka2_1:4_A64H,kka2_1:4_64,Kka2,kka2_1:4,P00552,1.0959,NO,64,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.496,-4.947,3.451,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.168804,0.00705578,1.0959 PSD95pdz3_V315N,PSD95pdz3_315,PSD95pdz3,PSD95pdz3,P31016,1.09596,NO,315,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.625,-3.963,2.338,5.52024,,,,,18.4557,4.054,,81.35,HHH,-1.62767,0.0758425,0.00153536,1.09596 beta-lactamase_0_A148L,beta-lactamase_0_148,TEM-1,beta-lactamase_0,P62593,1.09599,NO,148,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.757,-3.596,1.839,,0.379,H,A,0.46,-0.55,19.42,19.42,72.73,PHH,-1.40167,0.0500837,0.00547053,1.09599 PSD95pdz3_I314C,PSD95pdz3_314,PSD95pdz3,PSD95pdz3,P31016,1.09599,NO,314,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.628,-4.414,2.786,5.39919,,,,,15.7775,0.397,,81.35,BHH,-1.61167,0.0758425,0.0012606,1.09599 beta-lactamase_0_L49T,beta-lactamase_0_49,TEM-1,beta-lactamase_0,P62593,1.09603,NO,49,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.897,-1.853,-0.044,,0.131,T,A,0.55,0.04,13.838,13.838,64.69,AHP,-1.99233,0.0500837,0.00401477,1.09603 kka2_1:8_E17A,kka2_1:8_17,Kka2,kka2_1:8,P00552,1.0962,NO,17,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.154,-2.316,0.162,,0.957,T,A,1.04,0.22,31.483,31.483,63.64,HAB,-2.432,0.100394,0.00688738,1.0962 kka2_1:8_E17A,kka2_1:8_17,Kka2,kka2_1:8,P00552,1.0962,NO,17,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.154,-2.316,0.162,,0.957,T,A,1.04,0.22,31.483,31.483,63.64,HAB,-2.432,0.100394,0.00688738,1.0962 beta-lactamase_0_H156M,beta-lactamase_0_156,TEM-1,beta-lactamase_0,P62593,1.09622,NO,156,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-3.156,-3.543,0.387,,0.753,S,A,0.17,-0.6,23.367,23.367,77.62,ABH,-1.932,0.0500837,0.00468596,1.09622 kka2_1:8_R18S,kka2_1:8_18,Kka2,kka2_1:8,P00552,1.09624,NO,18,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.055,-2.892,0.837,,0.474,T,A,1.2,0.54,19.629,19.629,71.59,ABH,-1.821,0.100394,0.00724065,1.09624 kka2_1:8_R18S,kka2_1:8_18,Kka2,kka2_1:8,P00552,1.09624,NO,18,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.055,-2.892,0.837,,0.474,T,A,1.2,0.54,19.629,19.629,71.59,ABH,-1.821,0.100394,0.00724065,1.09624 PSD95pdz3_I314V,PSD95pdz3_314,PSD95pdz3,PSD95pdz3,P31016,1.09627,NO,314,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.628,-1.67,0.042,5.39919,,,,,15.7775,0.397,,81.35,BHH,-1.61167,0.0758425,0.0012606,1.09627 kka2_1:4_A247I,kka2_1:4_247,Kka2,kka2_1:4,P00552,1.09637,NO,247,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.459,-3.148,0.689,,1.01,S,A,0.46,0.65,,,92.05,HHH,-2.197,0.168804,0.0102428,1.09637 beta-lactamase_0_L160A,beta-lactamase_0_160,TEM-1,beta-lactamase_0,P62593,1.09638,NO,160,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.977,-3.094,2.117,,0.022,,B,0.55,-0.6,0.68,,44.41,BHA,-0.936,0.0500837,0.00193775,1.09638 beta-lactamase_0_V29N,beta-lactamase_0_29,TEM-1,beta-lactamase_0,P62593,1.09649,NO,29,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-2.856,-2.832,-0.024,,0.733,H,A,0.44,-0.78,21.916,21.916,93.01,HHB,-2.24733,0.0500837,0.00318969,1.09649 kka2_1:4_G55M,kka2_1:4_55,Kka2,kka2_1:4,P00552,1.09651,NO,55,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.625,-3.536,1.911,,0.517,S,b,0.75,1.19,15.753,15.753,63.64,POH,-2.05967,0.168804,0.00667877,1.09651 kka2_1:8_T51S,kka2_1:8_51,Kka2,kka2_1:8,P00552,1.09653,NO,51,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.199,-2.009,-0.19,,0.05,E,B,0.82,-0.05,5.399,,63.64,BPA,-1.76767,0.100394,0.00628861,1.09653 kka2_1:8_T51S,kka2_1:8_51,Kka2,kka2_1:8,P00552,1.09653,NO,51,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.199,-2.009,-0.19,,0.05,E,B,0.82,-0.05,5.399,,63.64,BPA,-1.76767,0.100394,0.00628861,1.09653 beta-lactamase_0_R189G,beta-lactamase_0_189,TEM-1,beta-lactamase_0,P62593,1.09655,NO,189,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.844,-3.504,1.66,,0.278,H,A,1.2,1.01,12.11,12.11,72.73,HBB,-1.668,0.0500837,0.0050699,1.09655 beta-lactamase_0_P250A,beta-lactamase_0_250,TEM-1,beta-lactamase_0,P62593,1.09658,NO,250,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-2.335,,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.0500837,0.00550899,1.09658 kka2_1:8_T85C,kka2_1:8_85,Kka2,kka2_1:8,P00552,1.09658,NO,85,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.165,-5.123,2.958,,0.576,E,B,0.22,1.39,22.154,22.154,71.59,HPA,-2.10133,0.100394,0.00634493,1.09658 kka2_1:8_T85C,kka2_1:8_85,Kka2,kka2_1:8,P00552,1.09658,NO,85,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.165,-5.123,2.958,,0.576,E,B,0.22,1.39,22.154,22.154,71.59,HPA,-2.10133,0.100394,0.00634493,1.09658 kka2_1:1_S68R,kka2_1:1_68,Kka2,kka2_1:1,P00552,1.09666,NO,68,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.623,-1.749,-0.874,,0.48,H,A,0.27,-0.1,2.655,,71.59,HPH,-1.40767,0.520039,0.00608265,1.09666 kka2_1:8_Q42L,kka2_1:8_42,Kka2,kka2_1:8,P00552,1.09671,NO,42,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.907,-2.953,0.046,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.100394,0.00679212,1.09671 kka2_1:8_Q42L,kka2_1:8_42,Kka2,kka2_1:8,P00552,1.09671,NO,42,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.907,-2.953,0.046,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.100394,0.00679212,1.09671 kka2_1:8_D118R,kka2_1:8_118,Kka2,kka2_1:8,P00552,1.0968,NO,118,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.07,-3.951,1.881,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.100394,0.0067852,1.0968 kka2_1:8_D118R,kka2_1:8_118,Kka2,kka2_1:8,P00552,1.0968,NO,118,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.07,-3.951,1.881,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.100394,0.0067852,1.0968 beta-lactamase_0_M66I,beta-lactamase_0_66,TEM-1,beta-lactamase_0,P62593,1.09681,NO,66,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.362,-2.521,1.159,,0.013,,A,0.55,-0.7,1.204,,73.08,OHH,-1.49567,0.0500837,0.00412876,1.09681 kka2_1:4_L152T,kka2_1:4_152,Kka2,kka2_1:4,P00552,1.09686,NO,152,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.521,-2.936,1.415,,0.547,,A,1.59,1.36,2.318,,63.64,OHH,-1.162,0.168804,0.00674868,1.09686 gb1_E268V,gb1_268,gb1,gb1,P06654,1.09689,NO,268,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.918,-2.343,0.425,,,,,,,0.637,,37.28,OAH,-1.59733,0.177985,0.00423953,1.09689 WW_domain_S183H,WW_domain_183,Yap65,WW_domain,P46937,1.09689,NO,183,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.95,-2.779,0.829,5.35576,,,,,,1.594,,83.93,PPP,-1.48733,0.153962,0.00445513,1.09689 beta-lactamase_0_T147G,beta-lactamase_0_147,TEM-1,beta-lactamase_0,P62593,1.09694,NO,147,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.149,-2.499,1.35,,0.281,H,A,0.22,-0.68,3.487,,64.34,HPH,-1.456,0.0500837,0.00226017,1.09694 PSD95pdz3_D366R,PSD95pdz3_366,PSD95pdz3,PSD95pdz3,P31016,1.09708,NO,366,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.264,-3.615,2.351,5.55684,,,,,20.2375,,,,HAH,-1.401,0.0758425,0.000481272,1.09708 PSD95pdz3_Q391I,PSD95pdz3_391,PSD95pdz3,PSD95pdz3,P31016,1.09713,NO,391,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-1.699,-3.692,1.993,5.50275,,,,,12.6589,,,,HPH,-1.481,0.0758425,0.000990786,1.09713 kka2_1:2_Q252H,kka2_1:2_252,Kka2,kka2_1:2,P00552,1.09714,NO,252,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.63,-3.494,0.864,,0.906,H,A,0.64,0.35,5.613,,92.05,PPB,-2.20733,0.295029,0.0121001,1.09714 kka2_1:8_P167A,kka2_1:8_167,Kka2,kka2_1:8,P00552,1.09714,NO,167,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-2.403,-1.382,-1.021,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.100394,0.00543203,1.09714 kka2_1:8_P167A,kka2_1:8_167,Kka2,kka2_1:8,P00552,1.09714,NO,167,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-2.403,-1.382,-1.021,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.100394,0.00543203,1.09714 beta-lactamase_0_F58Q,beta-lactamase_0_58,TEM-1,beta-lactamase_0,P62593,1.09716,NO,58,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-2.914,-2.803,-0.111,,0.266,E,B,0.58,-0.07,24.637,24.637,77.62,PHB,-2.059,0.0500837,0.00523369,1.09716 beta-lactamase_0_K30F,beta-lactamase_0_30,TEM-1,beta-lactamase_0,P62593,1.09719,NO,30,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-2.307,-4.338,2.031,,0.142,H,A,2.34,-0.65,1.491,,93.01,HBH,-2.32833,0.0500837,0.00448593,1.09719 beta-lactamase_0_Q203S,beta-lactamase_0_203,TEM-1,beta-lactamase_0,P62593,1.09728,NO,203,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.168,-2.824,0.656,,0.47,H,A,0.64,-0.38,14.541,14.541,65.38,BPP,-1.614,0.0500837,0.00631514,1.09728 beta-lactamase_39_V106G,beta-lactamase_39_106,TEM-1,beta-lactamase_39,P62593,1.09728,NO,106,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.218,-3.752,2.534,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.0495842,0.00304168,1.09728 kka2_1:1_E3D,kka2_1:1_3,Kka2,kka2_1:1,P00552,1.09731,NO,3,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.199,-1.902,-0.297,,,,,,,3.435,,92.05,HAP,-2.11567,0.520039,0.00267607,1.09731 kka2_1:4_A150Q,kka2_1:4_150,Kka2,kka2_1:4,P00552,1.09735,NO,150,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.949,-2.897,1.948,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.168804,0.0045009,1.09735 beta-lactamase_0_A282Q,beta-lactamase_0_282,TEM-1,beta-lactamase_0,P62593,1.09736,NO,282,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.586,,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.0500837,0.0449821,1.09736 kka2_1:2_I196V,kka2_1:2_196,Kka2,kka2_1:2,P00552,1.09736,NO,196,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-2.115,-2.455,0.34,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.295029,0.0107273,1.09736 kka2_1:8_R143E,kka2_1:8_143,Kka2,kka2_1:8,P00552,1.09737,NO,143,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.525,-2.41,-0.115,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.100394,0.00662247,1.09737 kka2_1:8_R143E,kka2_1:8_143,Kka2,kka2_1:8,P00552,1.09737,NO,143,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.525,-2.41,-0.115,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.100394,0.00662247,1.09737 beta-lactamase_0_N168A,beta-lactamase_0_168,TEM-1,beta-lactamase_0,P62593,1.09742,NO,168,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-1.029,-3.17,2.141,,0.113,G,A,0.61,-0.4,0.881,,44.41,HPA,-1.13233,0.0500837,0.00288667,1.09742 kka2_1:8_L152K,kka2_1:8_152,Kka2,kka2_1:8,P00552,1.09744,NO,152,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.521,-3.615,2.094,,0.547,.,A,0.55,1.36,1.442,,63.64,OHH,-1.162,0.100394,0.00674868,1.09744 kka2_1:8_L152K,kka2_1:8_152,Kka2,kka2_1:8,P00552,1.09744,NO,152,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.521,-3.615,2.094,,0.547,.,A,0.55,1.36,1.442,,63.64,OHH,-1.162,0.100394,0.00674868,1.09744 gb1_E268T,gb1_268,gb1,gb1,P06654,1.0975,NO,268,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.918,-3.262,1.344,,,,,,,0.637,,37.28,OAH,-1.59733,0.177985,0.00423953,1.0975 gb1_T277M,gb1_277,gb1,gb1,P06654,1.0975,NO,277,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.771,-4.392,2.621,,,,,,,0.824,,35.71,BPH,-1.54833,0.177985,0.00348258,1.0975 beta-lactamase_0_R92P,beta-lactamase_0_92,TEM-1,beta-lactamase_0,P62593,1.09751,NO,92,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.718,-3.033,1.315,,0.479,E,B,1.2,1.36,2.331,,65.38,BBH,-1.50367,0.0500837,0.00429626,1.09751 kka2_1:1_T28A,kka2_1:1_28,Kka2,kka2_1:1,P00552,1.09751,NO,28,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.883,-2.105,0.222,,0.353,S,B,0.22,2.02,1.12,,63.64,PPH,-1.74467,0.520039,0.00743084,1.09751 beta-lactamase_0_C75V,beta-lactamase_0_75,TEM-1,beta-lactamase_0,P62593,1.09759,NO,75,C,V,CV,Special,Hydrophobic,5.07,5.60847,0.538465,192,121,117,-4,108.5,140,31.5,-1.245,-3.383,2.138,,,H,A,0.46,-0.87,2.256,,50,HOO,-1.24333,0.0500837,0.0034616,1.09759 kka2_1:8_S54M,kka2_1:8_54,Kka2,kka2_1:8,P00552,1.09759,NO,54,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.471,-4.618,2.147,,0.408,S,b,0.77,1.01,13.679,13.679,71.59,HPO,-2.259,0.100394,0.00782867,1.09759 kka2_1:8_S54M,kka2_1:8_54,Kka2,kka2_1:8,P00552,1.09759,NO,54,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.471,-4.618,2.147,,0.408,S,b,0.77,1.01,13.679,13.679,71.59,HPO,-2.259,0.100394,0.00782867,1.09759 kka2_1:4_L39V,kka2_1:4_39,Kka2,kka2_1:4,P00552,1.09764,NO,39,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.223,-2.08,0.857,,,E,B,0.55,-1.21,1.998,,71.59,BHP,-1.69167,0.168804,0.00493618,1.09764 kka2_1:4_E161V,kka2_1:4_161,Kka2,kka2_1:4,P00552,1.09765,NO,161,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.581,-2.903,1.322,,0.829,G,A,1.52,2.24,1.612,,92.05,AAB,-1.861,0.168804,0.00760103,1.09765 kka2_1:8_R239I,kka2_1:8_239,Kka2,kka2_1:8,P00552,1.09776,NO,239,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.949,-3.142,0.193,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.100394,0.00835326,1.09776 kka2_1:8_R239I,kka2_1:8_239,Kka2,kka2_1:8,P00552,1.09776,NO,239,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.949,-3.142,0.193,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.100394,0.00835326,1.09776 kka2_1:4_G151K,kka2_1:4_151,Kka2,kka2_1:4,P00552,1.09783,NO,151,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.873,-3.594,2.721,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.168804,0.00339918,1.09783 PSD95pdz3_D332W,PSD95pdz3_332,PSD95pdz3,PSD95pdz3,P31016,1.09794,NO,332,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.264,-5.229,3.965,6.09878,,,,,48.762,,,,AAO,-1.22533,0.0758425,0.000937818,1.09794 kka2_1:4_E17P,kka2_1:4_17,Kka2,kka2_1:4,P00552,1.09797,NO,17,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.154,-2.799,0.645,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.168804,0.00688738,1.09797 kka2_1:2_G10S,kka2_1:2_10,Kka2,kka2_1:2,P00552,1.09798,NO,10,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.921,-3.23,1.309,,,,,,,2.192,,71.59,HOP,-2.10733,0.295029,0.00289233,1.09798 PSD95pdz3_I314M,PSD95pdz3_314,PSD95pdz3,PSD95pdz3,P31016,1.09799,NO,314,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.628,-3.807,2.179,5.39919,,,,,15.7775,0.397,,81.35,BHH,-1.61167,0.0758425,0.0012606,1.09799 beta-lactamase_0_F149S,beta-lactamase_0_149,TEM-1,beta-lactamase_0,P62593,1.09805,NO,149,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.299,-2.783,1.484,,0.195,H,A,0.58,0.11,3.518,,63.99,HHH,-1.46067,0.0500837,0.00418462,1.09805 kka2_1:8_R147C,kka2_1:8_147,Kka2,kka2_1:8,P00552,1.09806,NO,147,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.123,-5.216,4.093,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.100394,0.00549168,1.09806 kka2_1:8_R147C,kka2_1:8_147,Kka2,kka2_1:8,P00552,1.09806,NO,147,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.123,-5.216,4.093,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.100394,0.00549168,1.09806 kka2_1:4_T125L,kka2_1:4_125,Kka2,kka2_1:4,P00552,1.09808,NO,125,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.622,-3.575,0.953,,0.791,T,A,0.82,0.33,1.612,,92.05,BPH,-1.56933,0.168804,0.00821755,1.09808 kka2_1:2_A13W,kka2_1:2_13,Kka2,kka2_1:2,P00552,1.09813,NO,13,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.248,-3.869,1.621,,0.689,G,A,0.46,0.99,,,92.05,OHH,-1.646,0.295029,0.00784241,1.09813 beta-lactamase_0_E119A,beta-lactamase_0_119,TEM-1,beta-lactamase_0,P62593,1.09818,NO,119,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.412,-2.242,0.83,,0.358,H,A,1.04,0.51,3.396,,63.99,BAH,-1.623,0.0500837,0.00386966,1.09818 kka2_1:8_A168D,kka2_1:8_168,Kka2,kka2_1:8,P00552,1.09818,NO,168,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.989,-2.545,0.556,,0.67,H,A,0.46,0.15,11.329,11.329,64.39,OHA,-2.12933,0.100394,0.00806773,1.09818 kka2_1:8_A168D,kka2_1:8_168,Kka2,kka2_1:8,P00552,1.09818,NO,168,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.989,-2.545,0.556,,0.67,H,A,0.46,0.15,11.329,11.329,64.39,OHA,-2.12933,0.100394,0.00806773,1.09818 PSD95pdz3_H317G,PSD95pdz3_317,PSD95pdz3,PSD95pdz3,P31016,1.09822,NO,317,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-1.627,-3.04,1.413,6.19713,,,,,25.885,,,,HBB,-1.613,0.0758425,0.00111619,1.09822 kka2_1:2_F171L,kka2_1:2_171,Kka2,kka2_1:2,P00552,1.09825,NO,171,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.326,-1.818,0.492,,0.154,H,A,0.58,-0.1,2.645,,63.64,HHH,-1.45433,0.295029,0.00821426,1.09825 kka2_1:8_L47M,kka2_1:8_47,Kka2,kka2_1:8,P00552,1.09825,NO,47,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.265,-4.186,2.921,,0.139,E,B,1.59,-0.86,5.086,,63.26,HHH,-1.77933,0.100394,0.00509386,1.09825 kka2_1:8_L47M,kka2_1:8_47,Kka2,kka2_1:8,P00552,1.09825,NO,47,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.265,-4.186,2.921,,0.139,E,B,1.59,-0.86,5.086,,63.26,HHH,-1.77933,0.100394,0.00509386,1.09825 kka2_1:4_M116V,kka2_1:4_116,Kka2,kka2_1:4,P00552,1.09826,NO,116,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-2.482,-2.282,-0.2,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.168804,0.00745147,1.09826 beta-lactamase_0_R189W,beta-lactamase_0_189,TEM-1,beta-lactamase_0,P62593,1.0983,NO,189,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.844,-5.37,3.526,,0.278,H,A,1.2,1.01,12.11,12.11,72.73,HBB,-1.668,0.0500837,0.0050699,1.0983 PSD95pdz3_V315G,PSD95pdz3_315,PSD95pdz3,PSD95pdz3,P31016,1.09832,NO,315,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.625,-3.546,1.921,5.52024,,,,,18.4557,4.054,,81.35,HHH,-1.62767,0.0758425,0.00153536,1.09832 beta-lactamase_0_R275V,beta-lactamase_0_275,TEM-1,beta-lactamase_0,P62593,1.09841,NO,275,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.0500837,0.0141984,1.09841 beta-lactamase_39_M209T,beta-lactamase_39_209,TEM-1,beta-lactamase_39,P62593,1.09843,NO,209,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.442,-3.52,2.078,,,H,A,0.55,-0.97,1.167,,64.69,HHA,-1.52633,0.0495842,0.00625021,1.09843 beta-lactamase_0_I93R,beta-lactamase_0_93,TEM-1,beta-lactamase_0,P62593,1.09845,NO,93,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.401,-4.203,2.802,,0.128,E,B,0.48,0.44,1.266,,67.83,BHB,-1.873,0.0500837,0.00527066,1.09845 kka2_1:2_L193M,kka2_1:2_193,Kka2,kka2_1:2,P00552,1.09848,NO,193,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.983,-2.486,1.503,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.295029,0.00480179,1.09848 beta-lactamase_0_T138S,beta-lactamase_0_138,TEM-1,beta-lactamase_0,P62593,1.09853,NO,138,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.506,-2.455,-0.051,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.0500837,0.00487868,1.09853 beta-lactamase_39_H110Y,beta-lactamase_39_110,TEM-1,beta-lactamase_39,P62593,1.09854,NO,110,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-1.706,-2.513,0.807,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.0495842,0.00441499,1.09854 kka2_1:8_L152Q,kka2_1:8_152,Kka2,kka2_1:8,P00552,1.09854,NO,152,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.521,-2.735,1.214,,0.547,.,A,0.55,1.36,1.442,,63.64,OHH,-1.162,0.100394,0.00674868,1.09854 kka2_1:8_L152Q,kka2_1:8_152,Kka2,kka2_1:8,P00552,1.09854,NO,152,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.521,-2.735,1.214,,0.547,.,A,0.55,1.36,1.442,,63.64,OHH,-1.162,0.100394,0.00674868,1.09854 beta-lactamase_0_M270A,beta-lactamase_0_270,TEM-1,beta-lactamase_0,P62593,1.09855,NO,270,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.0500837,0.00767762,1.09855 beta-lactamase_0_L55C,beta-lactamase_0_55,TEM-1,beta-lactamase_0,P62593,1.09857,NO,55,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.86,-4.909,3.049,,0.372,E,A,0.55,-0.36,1.967,,63.99,HHA,-2.247,0.0500837,0.00403741,1.09857 kka2_1:8_M178A,kka2_1:8_178,Kka2,kka2_1:8,P00552,1.09862,NO,178,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-3.206,-2.643,-0.563,,0.554,,b,1.59,0.68,13.268,13.268,71.59,BHO,-2.154,0.100394,0.00717253,1.09862 kka2_1:8_M178A,kka2_1:8_178,Kka2,kka2_1:8,P00552,1.09862,NO,178,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-3.206,-2.643,-0.563,,0.554,,b,1.59,0.68,13.268,13.268,71.59,BHO,-2.154,0.100394,0.00717253,1.09862 PSD95pdz3_R313G,PSD95pdz3_313,PSD95pdz3,PSD95pdz3,P31016,1.09862,NO,313,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.582,-3.04,1.458,6.63563,,,,,18.3955,,,,BBH,-1.59733,0.0758425,0.000840067,1.09862 kka2_1:8_L53R,kka2_1:8_53,Kka2,kka2_1:8,P00552,1.09863,NO,53,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-2.681,-2.891,0.21,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.100394,0.00671168,1.09863 kka2_1:8_L53R,kka2_1:8_53,Kka2,kka2_1:8,P00552,1.09863,NO,53,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-2.681,-2.891,0.21,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.100394,0.00671168,1.09863 kka2_1:4_E230R,kka2_1:4_230,Kka2,kka2_1:4,P00552,1.09866,NO,230,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.672,-2.504,-0.168,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.168804,0.00920051,1.09866 kka2_1:4_P98R,kka2_1:4_98,Kka2,kka2_1:4,P00552,1.09867,NO,98,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.526,-2.723,1.197,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.168804,0.00622754,1.09867 kka2_1:8_G21R,kka2_1:8_21,Kka2,kka2_1:8,P00552,1.09868,NO,21,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.368,-3.948,2.58,,0.586,T,l,0.29,-0.75,4.889,,71.59,HOH,-2.10167,0.100394,0.00709648,1.09868 kka2_1:8_G21R,kka2_1:8_21,Kka2,kka2_1:8,P00552,1.09868,NO,21,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.368,-3.948,2.58,,0.586,T,l,0.29,-0.75,4.889,,71.59,HOH,-2.10167,0.100394,0.00709648,1.09868 kka2_1:8_V242Q,kka2_1:8_242,Kka2,kka2_1:8,P00552,1.09868,NO,242,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-2.687,-2.985,0.298,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.100394,0.0102575,1.09868 kka2_1:8_V242Q,kka2_1:8_242,Kka2,kka2_1:8,P00552,1.09868,NO,242,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-2.687,-2.985,0.298,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.100394,0.0102575,1.09868 kka2_1:4_R143S,kka2_1:4_143,Kka2,kka2_1:4,P00552,1.0987,NO,143,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.525,-3.022,0.497,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.168804,0.00662247,1.0987 beta-lactamase_0_D33A,beta-lactamase_0_33,TEM-1,beta-lactamase_0,P62593,1.09871,NO,33,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.321,-2.241,-0.08,,0.366,H,A,0.75,0.33,12.514,12.514,77.62,BAH,-2.12133,0.0500837,0.00435556,1.09871 gb1_D262G,gb1_262,gb1,gb1,P06654,1.09873,NO,262,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-3.132,-3.017,-0.115,,,,,,,1.304,,45.54,PAP,-2.05233,0.177985,0.00413102,1.09873 kka2_1:8_I2S,kka2_1:8_2,Kka2,kka2_1:8,P00552,1.0988,NO,2,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.787,-3.207,1.42,,,,,,,,,71.59,HHA,-1.92433,0.100394,0.00246644,1.0988 kka2_1:8_I2S,kka2_1:8_2,Kka2,kka2_1:8,P00552,1.0988,NO,2,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.787,-3.207,1.42,,,,,,,,,71.59,HHA,-1.92433,0.100394,0.00246644,1.0988 kka2_1:8_R239W,kka2_1:8_239,Kka2,kka2_1:8,P00552,1.09885,NO,239,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.949,-5.592,2.643,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.100394,0.00835326,1.09885 kka2_1:8_R239W,kka2_1:8_239,Kka2,kka2_1:8,P00552,1.09885,NO,239,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.949,-5.592,2.643,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.100394,0.00835326,1.09885 kka2_1:4_A247E,kka2_1:4_247,Kka2,kka2_1:4,P00552,1.09886,NO,247,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.459,-2.615,0.156,,1.01,S,A,0.46,0.65,,,92.05,HHH,-2.197,0.168804,0.0102428,1.09886 beta-lactamase_0_A182I,beta-lactamase_0_182,TEM-1,beta-lactamase_0,P62593,1.09887,NO,182,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.777,-3.851,2.074,,0.136,H,A,0.46,-0.66,10.765,10.765,93.01,OHH,-1.27367,0.0500837,0.00559099,1.09887 kka2_1:8_I246H,kka2_1:8_246,Kka2,kka2_1:8,P00552,1.09892,NO,246,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-2.008,-5.017,3.009,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.100394,0.0139479,1.09892 kka2_1:8_I246H,kka2_1:8_246,Kka2,kka2_1:8,P00552,1.09892,NO,246,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-2.008,-5.017,3.009,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.100394,0.0139479,1.09892 PSD95pdz3_H317F,PSD95pdz3_317,PSD95pdz3,PSD95pdz3,P31016,1.09898,NO,317,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-1.627,-3.524,1.897,6.19713,,,,,25.885,,,,HBB,-1.613,0.0758425,0.00111619,1.09898 kka2_1:4_L103W,kka2_1:4_103,Kka2,kka2_1:4,P00552,1.09899,NO,103,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-2.362,-5.448,3.086,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.168804,0.00574792,1.09899 PSD95pdz3_E334C,PSD95pdz3_334,PSD95pdz3,PSD95pdz3,P31016,1.099,NO,334,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.404,-4.994,3.59,5.60175,,,,,53.09,,,,OAO,-1.14,0.0758425,0.000912998,1.099 kka2_1:8_D127N,kka2_1:8_127,Kka2,kka2_1:8,P00552,1.09906,NO,127,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.364,-3.671,2.307,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.100394,0.00660501,1.09906 kka2_1:8_D127N,kka2_1:8_127,Kka2,kka2_1:8,P00552,1.09906,NO,127,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.364,-3.671,2.307,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.100394,0.00660501,1.09906 beta-lactamase_0_L197W,beta-lactamase_0_197,TEM-1,beta-lactamase_0,P62593,1.09908,NO,197,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.853,-5.146,4.293,,0.007,S,B,0.55,0.33,1.087,,60.14,HHP,-1.833,0.0500837,0.00144602,1.09908 PSD95pdz3_H317Y,PSD95pdz3_317,PSD95pdz3,PSD95pdz3,P31016,1.09918,NO,317,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-1.627,-2.944,1.317,6.19713,,,,,25.885,,,,HBB,-1.613,0.0758425,0.00111619,1.09918 kka2_1:8_A110K,kka2_1:8_110,Kka2,kka2_1:8,P00552,1.09919,NO,110,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.064,-3.119,1.055,,0.175,H,A,1.04,-1.19,11.413,11.413,71.59,OHA,-1.91867,0.100394,0.00759851,1.09919 kka2_1:8_A110K,kka2_1:8_110,Kka2,kka2_1:8,P00552,1.09919,NO,110,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.064,-3.119,1.055,,0.175,H,A,1.04,-1.19,11.413,11.413,71.59,OHA,-1.91867,0.100394,0.00759851,1.09919 kka2_1:8_F171Y,kka2_1:8_171,Kka2,kka2_1:8,P00552,1.09924,NO,171,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.326,-2.217,0.891,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.100394,0.00821426,1.09924 kka2_1:8_F171Y,kka2_1:8_171,Kka2,kka2_1:8,P00552,1.09924,NO,171,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.326,-2.217,0.891,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.100394,0.00821426,1.09924 beta-lactamase_0_T131H,beta-lactamase_0_131,TEM-1,beta-lactamase_0,P62593,1.09927,NO,131,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.328,-4.721,3.393,,,H,A,0.22,-0.69,3.306,,67.48,PPH,-1.00867,0.0500837,0.00345886,1.09927 beta-lactamase_0_V101Q,beta-lactamase_0_101,TEM-1,beta-lactamase_0,P62593,1.09929,NO,101,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.295,-4.106,2.811,,0.342,,B,0.44,0,1.61,,73.08,HHA,-1.54367,0.0500837,0.00374492,1.09929 kka2_1:2_D156G,kka2_1:2_156,Kka2,kka2_1:2,P00552,1.09936,NO,156,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.696,-3.383,1.687,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.295029,0.00926998,1.09936 beta-lactamase_0_I280W,beta-lactamase_0_280,TEM-1,beta-lactamase_0,P62593,1.09938,NO,280,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.0500837,0.0530888,1.09938 kka2_1:2_A168C,kka2_1:2_168,Kka2,kka2_1:2,P00552,1.09944,NO,168,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.989,-5.174,3.185,,0.67,H,A,0.46,0.15,25.546,25.546,64.39,OHA,-2.12933,0.295029,0.00806773,1.09944 kka2_1:8_Q26L,kka2_1:8_26,Kka2,kka2_1:8,P00552,1.09948,NO,26,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.18,-2.769,0.589,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.100394,0.00708962,1.09948 kka2_1:8_Q26L,kka2_1:8_26,Kka2,kka2_1:8,P00552,1.09948,NO,26,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.18,-2.769,0.589,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.100394,0.00708962,1.09948 kka2_1:4_Q155K,kka2_1:4_155,Kka2,kka2_1:4,P00552,1.09972,NO,155,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.606,-3.316,0.71,,0.525,T,A,0.64,1.49,1.592,,63.64,APA,-1.726,0.168804,0.00641853,1.09972 PSD95pdz3_E334T,PSD95pdz3_334,PSD95pdz3,PSD95pdz3,P31016,1.09975,NO,334,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.404,-3.103,1.699,5.60175,,,,,53.09,,,,OAO,-1.14,0.0758425,0.000912998,1.09975 beta-lactamase_0_D129R,beta-lactamase_0_129,TEM-1,beta-lactamase_0,P62593,1.09979,NO,129,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.816,-3.896,3.08,,,,B,0.75,-0.69,2.66,,34.97,PAP,-0.818,0.0500837,0.00109178,1.09979 beta-lactamase_39_L150M,beta-lactamase_39_150,TEM-1,beta-lactamase_39,P62593,1.09983,NO,150,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.326,-2.392,1.066,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.0495842,0.00463171,1.09983 kka2_1:8_R18G,kka2_1:8_18,Kka2,kka2_1:8,P00552,1.09993,NO,18,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.055,-3.057,1.002,,0.474,T,A,1.2,0.54,19.629,19.629,71.59,ABH,-1.821,0.100394,0.00724065,1.09993 kka2_1:8_R18G,kka2_1:8_18,Kka2,kka2_1:8,P00552,1.09993,NO,18,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.055,-3.057,1.002,,0.474,T,A,1.2,0.54,19.629,19.629,71.59,ABH,-1.821,0.100394,0.00724065,1.09993 kka2_1:4_Y22F,kka2_1:4_22,Kka2,kka2_1:4,P00552,1.10001,NO,22,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-1.583,-3.718,2.135,,0.122,.,B,0.21,-0.8,1.838,,65.53,OHA,-1.80333,0.168804,0.00598977,1.10001 beta-lactamase_0_K109A,beta-lactamase_0_109,TEM-1,beta-lactamase_0,P62593,1.10003,NO,109,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.734,-3.283,1.549,,0.787,G,A,2.34,2.21,15.473,15.473,72.73,ABB,-1.63333,0.0500837,0.00462493,1.10003 kka2_1:8_L39V,kka2_1:8_39,Kka2,kka2_1:8,P00552,1.10009,NO,39,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.223,-2.08,0.857,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.100394,0.00493618,1.10009 kka2_1:8_L39V,kka2_1:8_39,Kka2,kka2_1:8,P00552,1.10009,NO,39,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.223,-2.08,0.857,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.100394,0.00493618,1.10009 gb1_D262N,gb1_262,gb1,gb1,P06654,1.10012,NO,262,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-3.132,-3.417,0.285,,,,,,,1.304,,45.54,PAP,-2.05233,0.177985,0.00413102,1.10012 kka2_1:8_E86F,kka2_1:8_86,Kka2,kka2_1:8,P00552,1.10014,NO,86,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.86,-4.247,2.387,,0.369,,B,1.52,1.92,,,63.26,PAH,-1.98067,0.100394,0.00642858,1.10014 kka2_1:8_E86F,kka2_1:8_86,Kka2,kka2_1:8,P00552,1.10014,NO,86,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.86,-4.247,2.387,,0.369,,B,1.52,1.92,,,63.26,PAH,-1.98067,0.100394,0.00642858,1.10014 beta-lactamase_0_D212E,beta-lactamase_0_212,TEM-1,beta-lactamase_0,P62593,1.10018,NO,212,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.624,-3.306,1.682,,0.037,,b,0.75,-0.58,3.34,,74.48,HAB,-1.77667,0.0500837,0.00644302,1.10018 kka2_1:4_Q100D,kka2_1:4_100,Kka2,kka2_1:4,P00552,1.10022,NO,100,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.77,-3.173,0.403,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.168804,0.0066405,1.10022 kka2_1:8_A172V,kka2_1:8_172,Kka2,kka2_1:8,P00552,1.10022,NO,172,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.757,-2.683,0.926,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.100394,0.0079265,1.10022 kka2_1:8_A172V,kka2_1:8_172,Kka2,kka2_1:8,P00552,1.10022,NO,172,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.757,-2.683,0.926,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.100394,0.0079265,1.10022 beta-lactamase_0_S221Y,beta-lactamase_0_221,TEM-1,beta-lactamase_0,P62593,1.10023,NO,221,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.754,-4.278,2.524,,0.624,H,A,0.27,-0.2,2.914,,74.48,BPH,-1.59967,0.0500837,0.0046094,1.10023 beta-lactamase_39_I171T,beta-lactamase_39_171,TEM-1,beta-lactamase_39,P62593,1.10034,NO,171,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-2.431,-2.05,-0.381,,0.361,,B,0.48,0.53,16.954,16.954,77.62,HHO,-1.55533,0.0495842,0.00623355,1.10034 gb1_K239W,gb1_239,gb1,gb1,P06654,1.10038,NO,239,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-3.043,-5.24,2.197,,,,,,,1.326,,45.54,HBO,-2.31467,0.177985,0.00207004,1.10038 kka2_1:8_N200H,kka2_1:8_200,Kka2,kka2_1:8,P00552,1.10042,NO,200,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-2.446,-3.247,0.801,,0.756,T,L,0.43,-0.08,2.528,,64.39,APO,-2.08,0.100394,0.00838549,1.10042 kka2_1:8_N200H,kka2_1:8_200,Kka2,kka2_1:8,P00552,1.10042,NO,200,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-2.446,-3.247,0.801,,0.756,T,L,0.43,-0.08,2.528,,64.39,APO,-2.08,0.100394,0.00838549,1.10042 beta-lactamase_0_I280K,beta-lactamase_0_280,TEM-1,beta-lactamase_0,P62593,1.10046,NO,280,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.0500837,0.0530888,1.10046 beta-lactamase_0_R41L,beta-lactamase_0_41,TEM-1,beta-lactamase_0,P62593,1.10046,NO,41,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-0.942,-3.384,2.442,,0.321,E,B,1.2,-0.07,2.68,,65.03,HBH,-1.30267,0.0500837,0.00123327,1.10046 gb1_D266S,gb1_266,gb1,gb1,P06654,1.10046,NO,266,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.261,-3.11,1.849,,,,,,,0.638,,45.54,HAO,-1.59333,0.177985,0.00394694,1.10046 kka2_1:8_R177P,kka2_1:8_177,Kka2,kka2_1:8,P00552,1.10049,NO,177,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.282,-4.106,1.824,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.100394,0.00768224,1.10049 kka2_1:8_R177P,kka2_1:8_177,Kka2,kka2_1:8,P00552,1.10049,NO,177,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.282,-4.106,1.824,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.100394,0.00768224,1.10049 kka2_1:8_Q61E,kka2_1:8_61,Kka2,kka2_1:8,P00552,1.10052,NO,61,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.982,-2.773,-0.209,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.100394,0.00612092,1.10052 kka2_1:8_Q61E,kka2_1:8_61,Kka2,kka2_1:8,P00552,1.10052,NO,61,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.982,-2.773,-0.209,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.100394,0.00612092,1.10052 kka2_1:8_V16F,kka2_1:8_16,Kka2,kka2_1:8,P00552,1.10053,NO,16,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-3.087,-4.39,1.303,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.100394,0.00694011,1.10053 kka2_1:8_V16F,kka2_1:8_16,Kka2,kka2_1:8,P00552,1.10053,NO,16,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-3.087,-4.39,1.303,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.100394,0.00694011,1.10053 kka2_1:8_D183E,kka2_1:8_183,Kka2,kka2_1:8,P00552,1.10062,NO,183,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.204,-2.074,0.87,,0.518,.,b,0.75,0.25,0.347,,52.27,AAH,-1.40533,0.100394,0.00426304,1.10062 kka2_1:8_D183E,kka2_1:8_183,Kka2,kka2_1:8,P00552,1.10062,NO,183,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.204,-2.074,0.87,,0.518,.,b,0.75,0.25,0.347,,52.27,AAH,-1.40533,0.100394,0.00426304,1.10062 kka2_1:8_M116C,kka2_1:8_116,Kka2,kka2_1:8,P00552,1.10063,NO,116,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-2.482,-3.43,0.948,,,H,A,1.59,-0.88,4.659,,71.59,HHH,-1.63867,0.100394,0.00745147,1.10063 kka2_1:8_M116C,kka2_1:8_116,Kka2,kka2_1:8,P00552,1.10063,NO,116,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-2.482,-3.43,0.948,,,H,A,1.59,-0.88,4.659,,71.59,HHH,-1.63867,0.100394,0.00745147,1.10063 beta-lactamase_0_G234A,beta-lactamase_0_234,TEM-1,beta-lactamase_0,P62593,1.10071,NO,234,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.62,-2.853,2.233,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.0500837,0.000889577,1.10071 PSD95pdz3_I316A,PSD95pdz3_316,PSD95pdz3,PSD95pdz3,P31016,1.10075,NO,316,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.63,-2.759,1.129,5.46166,,,,,19.005,,,,HHB,-1.62733,0.0758425,0.00112762,1.10075 beta-lactamase_0_G154D,beta-lactamase_0_154,TEM-1,beta-lactamase_0,P62593,1.10084,NO,154,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.823,-2.317,1.494,,0.54,T,l,0.29,-0.56,3.629,,64.69,HOA,-1.635,0.0500837,0.00180205,1.10084 kka2_1:8_I254S,kka2_1:8_254,Kka2,kka2_1:8,P00552,1.10086,NO,254,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.933,-3.691,1.758,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.100394,0.0132375,1.10086 kka2_1:8_I254S,kka2_1:8_254,Kka2,kka2_1:8,P00552,1.10086,NO,254,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.933,-3.691,1.758,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.100394,0.0132375,1.10086 beta-lactamase_0_F58V,beta-lactamase_0_58,TEM-1,beta-lactamase_0,P62593,1.1009,NO,58,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-2.914,-3.697,0.783,,0.266,E,B,0.58,-0.07,24.637,24.637,77.62,PHB,-2.059,0.0500837,0.00523369,1.1009 beta-lactamase_0_A133M,beta-lactamase_0_133,TEM-1,beta-lactamase_0,P62593,1.10095,NO,133,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.186,-4.694,3.508,,,H,A,0.46,-0.86,2.148,,67.83,HHP,-0.988333,0.0500837,0.00468022,1.10095 kka2_1:4_D180S,kka2_1:4_180,Kka2,kka2_1:4,P00552,1.10095,NO,180,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.416,-2.79,0.374,,1.03,S,a,0.29,1.5,14.668,14.668,71.59,OAO,-2.02933,0.168804,0.00756412,1.10095 kka2_1:8_A247S,kka2_1:8_247,Kka2,kka2_1:8,P00552,1.10095,NO,247,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.459,-2.453,-0.006,,1.01,S,A,0.46,0.65,18.904,18.904,92.05,HHH,-2.197,0.100394,0.0102428,1.10095 kka2_1:8_A247S,kka2_1:8_247,Kka2,kka2_1:8,P00552,1.10095,NO,247,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.459,-2.453,-0.006,,1.01,S,A,0.46,0.65,18.904,18.904,92.05,HHH,-2.197,0.100394,0.0102428,1.10095 kka2_1:8_H139N,kka2_1:8_139,Kka2,kka2_1:8,P00552,1.10098,NO,139,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-2.809,-2.773,-0.036,,0.471,H,A,0.17,0.68,28.583,28.583,63.64,BBB,-2.22,0.100394,0.00734779,1.10098 kka2_1:8_H139N,kka2_1:8_139,Kka2,kka2_1:8,P00552,1.10098,NO,139,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-2.809,-2.773,-0.036,,0.471,H,A,0.17,0.68,28.583,28.583,63.64,BBB,-2.22,0.100394,0.00734779,1.10098 beta-lactamase_0_L219V,beta-lactamase_0_219,TEM-1,beta-lactamase_0,P62593,1.101,NO,219,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.313,-2.847,1.534,,,I,A,0.55,-0.51,6.513,6.513,74.48,HHB,-1.21533,0.0500837,0.00664345,1.101 beta-lactamase_0_I93D,beta-lactamase_0_93,TEM-1,beta-lactamase_0,P62593,1.10102,NO,93,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.401,-4.003,2.602,,0.128,E,B,0.48,0.44,1.266,,67.83,BHB,-1.873,0.0500837,0.00527066,1.10102 kka2_1:4_Q26W,kka2_1:4_26,Kka2,kka2_1:4,P00552,1.10104,NO,26,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.18,-5.501,3.321,,0.448,E,B,0.4,0.44,5.022,,92.05,HPP,-2.11167,0.168804,0.00708962,1.10104 beta-lactamase_0_V72I,beta-lactamase_0_72,TEM-1,beta-lactamase_0,P62593,1.10109,NO,72,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.658,-3.311,1.653,,,H,A,0.44,-1.03,2.964,,65.73,BHH,-1.32167,0.0500837,0.00501194,1.10109 WW_domain_T198Q,WW_domain_198,Yap65,WW_domain,P46937,1.10109,NO,198,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.451,-3.872,2.421,5.14348,,,,,,3.158,,70.04,PPH,-1.513,0.153962,0.00224534,1.10109 beta-lactamase_0_W163Q,beta-lactamase_0_163,TEM-1,beta-lactamase_0,P62593,1.10113,NO,163,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-1.843,-2.929,1.086,,0.467,,B,0.47,-0.5,13.843,13.843,63.99,BHA,-1.269,0.0500837,0.00418955,1.10113 PSD95pdz3_G333R,PSD95pdz3_333,PSD95pdz3,PSD95pdz3,P31016,1.10113,NO,333,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.008,-3.615,2.607,5.09445,,,,,48.755,,,,AOA,-1.22533,0.0758425,0.00092544,1.10113 kka2_1:8_E230N,kka2_1:8_230,Kka2,kka2_1:8,P00552,1.10117,NO,230,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.672,-3.821,1.149,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.100394,0.00920051,1.10117 kka2_1:8_E230N,kka2_1:8_230,Kka2,kka2_1:8,P00552,1.10117,NO,230,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.672,-3.821,1.149,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.100394,0.00920051,1.10117 PSD95pdz3_T321D,PSD95pdz3_321,PSD95pdz3,PSD95pdz3,P31016,1.10122,NO,321,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.391,-3.15,1.759,5.19953,,,,,20.3371,,,,PPO,-1.306,0.0758425,0.00106992,1.10122 gb1_T243G,gb1_243,gb1,gb1,P06654,1.10132,NO,243,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.415,-2.996,1.581,,,,,,,1.083,,37.28,PPP,-1.43233,0.177985,0.00308687,1.10132 beta-lactamase_0_A148E,beta-lactamase_0_148,TEM-1,beta-lactamase_0,P62593,1.10133,NO,148,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.757,-2.317,0.56,,0.379,H,A,0.46,-0.55,19.42,19.42,72.73,PHH,-1.40167,0.0500837,0.00547053,1.10133 kka2_1:8_P128F,kka2_1:8_128,Kka2,kka2_1:8,P00552,1.10134,NO,128,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.922,-4.049,2.127,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.100394,0.00774689,1.10134 kka2_1:8_P128F,kka2_1:8_128,Kka2,kka2_1:8,P00552,1.10134,NO,128,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.922,-4.049,2.127,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.100394,0.00774689,1.10134 kka2_1:8_S68I,kka2_1:8_68,Kka2,kka2_1:8,P00552,1.10134,NO,68,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.623,-4.041,1.418,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.100394,0.00608265,1.10134 kka2_1:8_S68I,kka2_1:8_68,Kka2,kka2_1:8,P00552,1.10134,NO,68,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.623,-4.041,1.418,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.100394,0.00608265,1.10134 kka2_1:8_A150H,kka2_1:8_150,Kka2,kka2_1:8,P00552,1.1014,NO,150,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.949,-4.695,3.746,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.100394,0.0045009,1.1014 kka2_1:8_A150H,kka2_1:8_150,Kka2,kka2_1:8,P00552,1.1014,NO,150,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.949,-4.695,3.746,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.100394,0.0045009,1.1014 kka2_1:8_K175E,kka2_1:8_175,Kka2,kka2_1:8,P00552,1.1014,NO,175,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-2.897,-2.454,-0.443,,0.579,H,A,2.34,0.51,15.316,15.316,71.59,HBH,-1.82333,0.100394,0.00693093,1.1014 kka2_1:8_K175E,kka2_1:8_175,Kka2,kka2_1:8,P00552,1.1014,NO,175,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-2.897,-2.454,-0.443,,0.579,H,A,2.34,0.51,15.316,15.316,71.59,HBH,-1.82333,0.100394,0.00693093,1.1014 kka2_1:4_I196F,kka2_1:4_196,Kka2,kka2_1:4,P00552,1.10145,NO,196,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-2.115,-1.503,-0.612,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.168804,0.0107273,1.10145 PSD95pdz3_T385R,PSD95pdz3_385,PSD95pdz3,PSD95pdz3,P31016,1.10145,NO,385,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.533,-3.485,1.952,5.57157,,,,,23.6871,4.527,,87.71,PPH,-1.56567,0.0758425,0.000545119,1.10145 beta-lactamase_0_V106Y,beta-lactamase_0_106,TEM-1,beta-lactamase_0,P62593,1.10148,NO,106,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.218,-3.895,2.677,,0.258,T,A,0.44,0.24,0.952,,72.73,OHP,-1.04933,0.0500837,0.00304168,1.10148 kka2_1:8_E160C,kka2_1:8_160,Kka2,kka2_1:8,P00552,1.10151,NO,160,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.683,-5.219,3.536,,0.989,G,A,1.04,2.28,2.164,,71.59,AAA,-1.36133,0.100394,0.00935762,1.10151 kka2_1:8_E160C,kka2_1:8_160,Kka2,kka2_1:8,P00552,1.10151,NO,160,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.683,-5.219,3.536,,0.989,G,A,1.04,2.28,2.164,,71.59,AAA,-1.36133,0.100394,0.00935762,1.10151 kka2_1:8_P167V,kka2_1:8_167,Kka2,kka2_1:8,P00552,1.10152,NO,167,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-2.403,-2.424,0.021,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.100394,0.00543203,1.10152 kka2_1:8_P167V,kka2_1:8_167,Kka2,kka2_1:8,P00552,1.10152,NO,167,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-2.403,-2.424,0.021,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.100394,0.00543203,1.10152 kka2_1:8_V46P,kka2_1:8_46,Kka2,kka2_1:8,P00552,1.10154,NO,46,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-2.62,-2.348,-0.272,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.100394,0.00631301,1.10154 kka2_1:8_V46P,kka2_1:8_46,Kka2,kka2_1:8,P00552,1.10154,NO,46,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-2.62,-2.348,-0.272,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.100394,0.00631301,1.10154 beta-lactamase_0_E166A,beta-lactamase_0_166,TEM-1,beta-lactamase_0,P62593,1.10162,NO,166,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.756,-2.056,0.3,,0.508,G,A,1.04,1.05,17.227,17.227,73.08,OAH,-1.42233,0.0500837,0.00512989,1.10162 kka2_1:8_A71I,kka2_1:8_71,Kka2,kka2_1:8,P00552,1.10167,NO,71,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.824,-4.1,2.276,,0.553,H,A,0.46,0.08,18.64,18.64,64.39,HHP,-1.74033,0.100394,0.00727707,1.10167 kka2_1:8_A71I,kka2_1:8_71,Kka2,kka2_1:8,P00552,1.10167,NO,71,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.824,-4.1,2.276,,0.553,H,A,0.46,0.08,18.64,18.64,64.39,HHP,-1.74033,0.100394,0.00727707,1.10167 kka2_1:1_F20S,kka2_1:1_20,Kka2,kka2_1:1,P00552,1.10172,NO,20,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-3.354,-2.147,-1.207,,0.935,T,B,0.58,-0.41,1.657,,92.05,HHO,-1.992,0.520039,0.00701744,1.10172 kka2_1:8_V198S,kka2_1:8_198,Kka2,kka2_1:8,P00552,1.10175,NO,198,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.719,-2.746,1.027,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.100394,0.00835002,1.10175 kka2_1:8_V198S,kka2_1:8_198,Kka2,kka2_1:8,P00552,1.10175,NO,198,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.719,-2.746,1.027,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.100394,0.00835002,1.10175 kka2_1:8_A56L,kka2_1:8_56,Kka2,kka2_1:8,P00552,1.10181,NO,56,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.083,-2.797,0.714,,0.796,T,A,0.46,1.39,10.511,,71.59,OHH,-1.86867,0.100394,0.00717715,1.10181 kka2_1:8_A56L,kka2_1:8_56,Kka2,kka2_1:8,P00552,1.10181,NO,56,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.083,-2.797,0.714,,0.796,T,A,0.46,1.39,10.511,,71.59,OHH,-1.86867,0.100394,0.00717715,1.10181 kka2_1:8_A79Y,kka2_1:8_79,Kka2,kka2_1:8,P00552,1.10181,NO,79,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.368,-4.411,2.043,,0.563,.,B,0.46,-0.43,,,71.59,HHH,-1.752,0.100394,0.00664821,1.10181 kka2_1:8_A79Y,kka2_1:8_79,Kka2,kka2_1:8,P00552,1.10181,NO,79,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.368,-4.411,2.043,,0.563,.,B,0.46,-0.43,,,71.59,HHH,-1.752,0.100394,0.00664821,1.10181 kka2_1:8_S54T,kka2_1:8_54,Kka2,kka2_1:8,P00552,1.10186,NO,54,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.471,-2.979,0.508,,0.408,S,b,0.77,1.01,13.679,13.679,71.59,HPO,-2.259,0.100394,0.00782867,1.10186 kka2_1:8_S54T,kka2_1:8_54,Kka2,kka2_1:8,P00552,1.10186,NO,54,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.471,-2.979,0.508,,0.408,S,b,0.77,1.01,13.679,13.679,71.59,HPO,-2.259,0.100394,0.00782867,1.10186 kka2_1:8_Q100E,kka2_1:8_100,Kka2,kka2_1:8,P00552,1.10193,NO,100,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.77,-2.743,-0.027,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.100394,0.0066405,1.10193 kka2_1:8_Q100E,kka2_1:8_100,Kka2,kka2_1:8,P00552,1.10193,NO,100,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.77,-2.743,-0.027,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.100394,0.0066405,1.10193 kka2_1:4_E111I,kka2_1:4_111,Kka2,kka2_1:4,P00552,1.10195,NO,111,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.28,-4.031,1.751,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.168804,0.00746789,1.10195 kka2_1:8_V75W,kka2_1:8_75,Kka2,kka2_1:8,P00552,1.10197,NO,75,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-2.06,-5.286,3.226,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.100394,0.00693733,1.10197 kka2_1:8_V75W,kka2_1:8_75,Kka2,kka2_1:8,P00552,1.10197,NO,75,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-2.06,-5.286,3.226,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.100394,0.00693733,1.10197 kka2_1:4_A129W,kka2_1:4_129,Kka2,kka2_1:4,P00552,1.10209,NO,129,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.656,-5.587,3.931,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.168804,0.00726862,1.10209 PSD95pdz3_G335V,PSD95pdz3_335,PSD95pdz3,PSD95pdz3,P31016,1.10219,NO,335,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.008,-3.435,2.427,4.76223,,,,,22.4225,,,,AOH,-1.34733,0.0758425,0.000900493,1.10219 kka2_1:2_R173H,kka2_1:2_173,Kka2,kka2_1:2,P00552,1.10226,NO,173,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.407,-4.589,2.182,,0.308,H,A,0.16,-0.13,15.389,15.389,65.53,HBH,-1.70533,0.295029,0.00784999,1.10226 kka2_1:4_A79S,kka2_1:4_79,Kka2,kka2_1:4,P00552,1.10228,NO,79,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.368,-2.87,0.502,,0.563,.,B,0.46,-0.43,2.291,,71.59,HHH,-1.752,0.168804,0.00664821,1.10228 beta-lactamase_0_L79Q,beta-lactamase_0_79,TEM-1,beta-lactamase_0,P62593,1.10232,NO,79,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.842,-4.087,3.245,,0.007,H,A,0.55,-0.16,5.053,,50.35,HHP,-1.44333,0.0500837,0.000947397,1.10232 PSD95pdz3_I314T,PSD95pdz3_314,PSD95pdz3,PSD95pdz3,P31016,1.10236,NO,314,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.628,-3.102,1.474,5.39919,,,,,15.7775,0.397,,81.35,BHH,-1.61167,0.0758425,0.0012606,1.10236 beta-lactamase_0_A84S,beta-lactamase_0_84,TEM-1,beta-lactamase_0,P62593,1.10242,NO,84,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.651,-2.609,0.958,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.0500837,0.00503822,1.10242 beta-lactamase_0_R59F,beta-lactamase_0_59,TEM-1,beta-lactamase_0,P62593,1.10243,NO,59,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.345,-4.379,3.034,,0.329,S,L,1.2,-0.09,2.919,,73.08,HBO,-2.24267,0.0500837,0.00318082,1.10243 beta-lactamase_39_M209A,beta-lactamase_39_209,TEM-1,beta-lactamase_39,P62593,1.1025,NO,209,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.442,-3.177,1.735,,,H,A,0.55,-0.97,1.167,,64.69,HHA,-1.52633,0.0495842,0.00625021,1.1025 beta-lactamase_0_K286R,beta-lactamase_0_286,TEM-1,beta-lactamase_0,P62593,1.10251,NO,286,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.0500837,,1.10251 beta-lactamase_0_G85F,beta-lactamase_0_85,TEM-1,beta-lactamase_0,P62593,1.10252,NO,85,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.011,-4.377,3.366,,0.805,T,l,0.29,1.7,2.25,,63.64,HOP,-1.68733,0.0500837,0.00252173,1.10252 beta-lactamase_0_P255T,beta-lactamase_0_255,TEM-1,beta-lactamase_0,P62593,1.10261,NO,255,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.0500837,0.00499612,1.10261 kka2_1:8_D180I,kka2_1:8_180,Kka2,kka2_1:8,P00552,1.10265,NO,180,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.416,-3.372,0.956,,1.03,S,a,0.75,1.5,14.668,14.668,71.59,OAO,-2.02933,0.100394,0.00756412,1.10265 kka2_1:8_D180I,kka2_1:8_180,Kka2,kka2_1:8,P00552,1.10265,NO,180,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.416,-3.372,0.956,,1.03,S,a,0.75,1.5,14.668,14.668,71.59,OAO,-2.02933,0.100394,0.00756412,1.10265 kka2_1:8_D5Q,kka2_1:8_5,Kka2,kka2_1:8,P00552,1.10267,NO,5,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.306,-3.312,2.006,,,,,,,1.147,,71.59,PAO,-1.784,0.100394,0.00222864,1.10267 kka2_1:8_D5Q,kka2_1:8_5,Kka2,kka2_1:8,P00552,1.10267,NO,5,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.306,-3.312,2.006,,,,,,,1.147,,71.59,PAO,-1.784,0.100394,0.00222864,1.10267 beta-lactamase_0_E272P,beta-lactamase_0_272,TEM-1,beta-lactamase_0,P62593,1.10268,NO,272,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.0500837,0.00545371,1.10268 beta-lactamase_0_I206Q,beta-lactamase_0_206,TEM-1,beta-lactamase_0,P62593,1.10269,NO,206,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-2.429,-2.554,0.125,,0.173,H,A,0.48,-0.34,3.411,,77.62,HHA,-1.805,0.0500837,0.00528934,1.10269 beta-lactamase_0_I245T,beta-lactamase_0_245,TEM-1,beta-lactamase_0,P62593,1.10269,NO,245,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.0500837,0.00391032,1.10269 kka2_1:4_Q27I,kka2_1:4_27,Kka2,kka2_1:4,P00552,1.10271,NO,27,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-1.659,-3.006,1.347,,0.608,,A,0.4,0.71,1.498,,65.53,PPP,-1.90733,0.168804,0.00595365,1.10271 kka2_1:2_Q136V,kka2_1:2_136,Kka2,kka2_1:2,P00552,1.10272,NO,136,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-3.021,-3.774,0.753,,0.331,,b,0.4,0.96,2.726,,92.05,BPH,-2.16933,0.295029,0.00624149,1.10272 PSD95pdz3_S320E,PSD95pdz3_320,PSD95pdz3,PSD95pdz3,P31016,1.10283,NO,320,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.519,-2.897,1.378,5.81757,,,,,21.4517,,,,OPP,-1.306,0.0758425,0.00108158,1.10283 beta-lactamase_0_R257K,beta-lactamase_0_257,TEM-1,beta-lactamase_0,P62593,1.10285,NO,257,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.533,,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.0500837,0.00756629,1.10285 kka2_1:2_A87Q,kka2_1:2_87,Kka2,kka2_1:2,P00552,1.10287,NO,87,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.917,-3.008,1.091,,1.039,S,L,0.46,1.57,22.675,22.675,65.53,AHO,-1.822,0.295029,0.00791281,1.10287 gb1_E268I,gb1_268,gb1,gb1,P06654,1.10294,NO,268,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.918,-3.52,1.602,,,,,,,0.637,,37.28,OAH,-1.59733,0.177985,0.00423953,1.10294 kka2_1:8_D250R,kka2_1:8_250,Kka2,kka2_1:8,P00552,1.10302,NO,250,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.015,-3.871,2.856,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.100394,0.0177103,1.10302 kka2_1:8_D250R,kka2_1:8_250,Kka2,kka2_1:8,P00552,1.10302,NO,250,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.015,-3.871,2.856,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.100394,0.0177103,1.10302 kka2_1:4_G151M,kka2_1:4_151,Kka2,kka2_1:4,P00552,1.1031,NO,151,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.873,-4.939,4.066,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.168804,0.00339918,1.1031 beta-lactamase_2500_E210I,beta-lactamase_2500_210,TEM-1,beta-lactamase_2500,P62593,1.10316,NO,210,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.319,-2.456,0.137,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.361275,0.00663582,1.10316 kka2_1:2_A9E,kka2_1:2_9,Kka2,kka2_1:2,P00552,1.10321,NO,9,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.079,-3.534,1.455,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.295029,0.00273264,1.10321 kka2_1:2_S54M,kka2_1:2_54,Kka2,kka2_1:2,P00552,1.10322,NO,54,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.471,-4.618,2.147,,0.408,S,b,0.27,1.01,0.393,,71.59,HPO,-2.259,0.295029,0.00782867,1.10322 kka2_1:4_F171L,kka2_1:4_171,Kka2,kka2_1:4,P00552,1.10324,NO,171,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.326,-1.818,0.492,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.168804,0.00821426,1.10324 beta-lactamase_39_V106C,beta-lactamase_39_106,TEM-1,beta-lactamase_39,P62593,1.10333,NO,106,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.218,-4.774,3.556,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.0495842,0.00304168,1.10333 kka2_1:4_A176K,kka2_1:4_176,Kka2,kka2_1:4,P00552,1.10333,NO,176,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.621,-2.698,1.077,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.168804,0.0083587,1.10333 kka2_1:8_S104T,kka2_1:8_104,Kka2,kka2_1:8,P00552,1.10336,NO,104,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.436,-2.284,0.848,,0.536,T,A,0.27,-1.11,1.689,,63.64,HPP,-1.91433,0.100394,0.00555207,1.10336 kka2_1:8_S104T,kka2_1:8_104,Kka2,kka2_1:8,P00552,1.10336,NO,104,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.436,-2.284,0.848,,0.536,T,A,0.27,-1.11,1.689,,63.64,HPP,-1.91433,0.100394,0.00555207,1.10336 beta-lactamase_0_T193C,beta-lactamase_0_193,TEM-1,beta-lactamase_0,P62593,1.1034,NO,193,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.914,-4.857,2.943,,0.439,H,a,0.22,0.33,11.546,11.546,63.99,HPO,-1.52133,0.0500837,0.00482669,1.1034 PSD95pdz3_P311C,PSD95pdz3_311,PSD95pdz3,PSD95pdz3,P31016,1.10341,NO,311,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.236,-4.769,3.533,5.76649,,,,,14.78,,,,OOB,-1.409,0.0758425,0.0030796,1.10341 PSD95pdz3_L342K,PSD95pdz3_342,PSD95pdz3,PSD95pdz3,P31016,1.10348,NO,342,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.347,-3.364,2.017,5.03015,,,,,12.0762,,,,HHH,-1.428,0.0758425,0.00081112,1.10348 kka2_1:8_D154T,kka2_1:8_154,Kka2,kka2_1:8,P00552,1.10357,NO,154,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.876,-3.472,2.596,,0.457,,b,0.29,1.48,0.844,,52.65,HAP,-1.52467,0.100394,0.00292633,1.10357 kka2_1:8_D154T,kka2_1:8_154,Kka2,kka2_1:8,P00552,1.10357,NO,154,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.876,-3.472,2.596,,0.457,,b,0.29,1.48,0.844,,52.65,HAP,-1.52467,0.100394,0.00292633,1.10357 beta-lactamase_0_K232H,beta-lactamase_0_232,TEM-1,beta-lactamase_0,P62593,1.10362,NO,232,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.012,-4.433,3.421,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.0500837,0.00313441,1.10362 beta-lactamase_39_W208N,beta-lactamase_39_208,TEM-1,beta-lactamase_39,P62593,1.10362,NO,208,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-0.818,-4.348,3.53,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.0495842,0.00126609,1.10362 beta-lactamase_0_E210Q,beta-lactamase_0_210,TEM-1,beta-lactamase_0,P62593,1.10363,NO,210,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.319,-2.627,0.308,,0.476,H,A,1.04,0.75,3.618,,77.62,HAH,-1.88567,0.0500837,0.00663582,1.10363 kka2_1:8_D154I,kka2_1:8_154,Kka2,kka2_1:8,P00552,1.10363,NO,154,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.876,-4.094,3.218,,0.457,,b,0.29,1.48,0.844,,52.65,HAP,-1.52467,0.100394,0.00292633,1.10363 kka2_1:8_D154I,kka2_1:8_154,Kka2,kka2_1:8,P00552,1.10363,NO,154,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.876,-4.094,3.218,,0.457,,b,0.29,1.48,0.844,,52.65,HAP,-1.52467,0.100394,0.00292633,1.10363 beta-lactamase_0_P25H,beta-lactamase_0_25,TEM-1,beta-lactamase_0,P62593,1.10366,NO,25,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.526,-4.604,3.078,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.0500837,0.00347571,1.10366 kka2_1:2_E161N,kka2_1:2_161,Kka2,kka2_1:2,P00552,1.10368,NO,161,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.581,-3.715,2.134,,0.829,G,A,1.52,2.24,1.612,,92.05,AAB,-1.861,0.295029,0.00760103,1.10368 WW_domain_D170E,WW_domain_170,Yap65,WW_domain,P46937,1.10368,NO,170,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.213,-1.867,0.654,,,,,,,0.399,,15.87,OAH,-1.38,0.153962,0.00123319,1.10368 kka2_1:8_I246A,kka2_1:8_246,Kka2,kka2_1:8,P00552,1.10369,NO,246,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-2.008,-2.246,0.238,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.100394,0.0139479,1.10369 kka2_1:8_I246A,kka2_1:8_246,Kka2,kka2_1:8,P00552,1.10369,NO,246,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-2.008,-2.246,0.238,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.100394,0.0139479,1.10369 gb1_E268R,gb1_268,gb1,gb1,P06654,1.1037,NO,268,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.918,-3.464,1.546,,,,,,,0.637,,37.28,OAH,-1.59733,0.177985,0.00423953,1.1037 beta-lactamase_0_D155T,beta-lactamase_0_155,TEM-1,beta-lactamase_0,P62593,1.10374,NO,155,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.889,-3.445,2.556,,0.049,,B,0.75,-0.9,16.833,16.833,64.69,OAB,-1.62267,0.0500837,0.00135315,1.10374 beta-lactamase_0_R239F,beta-lactamase_0_239,TEM-1,beta-lactamase_0,P62593,1.10384,NO,239,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.0500837,0.00213852,1.10384 gb1_D273P,gb1_273,gb1,gb1,P06654,1.10387,NO,273,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.998,-2.363,0.365,,,,,,,3.514,3.514,37.28,AAH,-1.72767,0.177985,0.00318903,1.10387 kka2_1:4_G21D,kka2_1:4_21,Kka2,kka2_1:4,P00552,1.10396,NO,21,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.368,-1.988,0.62,,0.586,T,l,0.75,-0.75,3.075,,71.59,HOH,-2.10167,0.168804,0.00709648,1.10396 PSD95pdz3_V315C,PSD95pdz3_315,PSD95pdz3,PSD95pdz3,P31016,1.10398,NO,315,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.625,-4.477,2.852,5.52024,,,,,18.4557,4.054,,81.35,HHH,-1.62767,0.0758425,0.00153536,1.10398 kka2_1:8_L47T,kka2_1:8_47,Kka2,kka2_1:8,P00552,1.10401,NO,47,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.265,-3.56,2.295,,0.139,E,B,1.59,-0.86,5.086,,63.26,HHH,-1.77933,0.100394,0.00509386,1.10401 kka2_1:8_L47T,kka2_1:8_47,Kka2,kka2_1:8,P00552,1.10401,NO,47,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.265,-3.56,2.295,,0.139,E,B,1.59,-0.86,5.086,,63.26,HHH,-1.77933,0.100394,0.00509386,1.10401 kka2_1:8_L260M,kka2_1:8_260,Kka2,kka2_1:8,P00552,1.10403,NO,260,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.741,-3.833,3.092,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.100394,0.0233782,1.10403 kka2_1:8_L260M,kka2_1:8_260,Kka2,kka2_1:8,P00552,1.10403,NO,260,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.741,-3.833,3.092,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.100394,0.0233782,1.10403 beta-lactamase_0_K190D,beta-lactamase_0_190,TEM-1,beta-lactamase_0,P62593,1.10416,NO,190,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.994,-3.691,1.697,,0.371,H,A,2.34,0.16,16.606,16.606,77.62,BBH,-1.64167,0.0500837,0.00574527,1.10416 kka2_1:8_D154C,kka2_1:8_154,Kka2,kka2_1:8,P00552,1.1042,NO,154,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.876,-5.188,4.312,,0.457,,b,0.29,1.48,0.844,,52.65,HAP,-1.52467,0.100394,0.00292633,1.1042 kka2_1:8_D154C,kka2_1:8_154,Kka2,kka2_1:8,P00552,1.1042,NO,154,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.876,-5.188,4.312,,0.457,,b,0.29,1.48,0.844,,52.65,HAP,-1.52467,0.100394,0.00292633,1.1042 PSD95pdz3_E352R,PSD95pdz3_352,PSD95pdz3,PSD95pdz3,P31016,1.10424,NO,352,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.587,-3.344,1.757,5.49659,,,,,24.2,2.525,,86.88,OAH,-1.314,0.0758425,0.000892231,1.10424 beta-lactamase_39_V214K,beta-lactamase_39_214,TEM-1,beta-lactamase_39,P62593,1.10425,NO,214,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.299,-3.699,2.4,,0.375,S,A,0.44,-0.44,18.838,18.838,74.48,BHH,-1.53733,0.0495842,0.00628442,1.10425 kka2_1:8_D180G,kka2_1:8_180,Kka2,kka2_1:8,P00552,1.10426,NO,180,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.416,-2.606,0.19,,1.03,S,a,0.75,1.5,14.668,14.668,71.59,OAO,-2.02933,0.100394,0.00756412,1.10426 kka2_1:8_D180G,kka2_1:8_180,Kka2,kka2_1:8,P00552,1.10426,NO,180,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.416,-2.606,0.19,,1.03,S,a,0.75,1.5,14.668,14.668,71.59,OAO,-2.02933,0.100394,0.00756412,1.10426 kka2_1:8_I115V,kka2_1:8_115,Kka2,kka2_1:8,P00552,1.1043,NO,115,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.606,-2.022,0.416,,0.105,H,A,1.52,-1.18,4.064,,65.53,PHH,-2.205,0.100394,0.00836567,1.1043 kka2_1:8_I115V,kka2_1:8_115,Kka2,kka2_1:8,P00552,1.1043,NO,115,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.606,-2.022,0.416,,0.105,H,A,1.52,-1.18,4.064,,65.53,PHH,-2.205,0.100394,0.00836567,1.1043 kka2_1:4_D156E,kka2_1:4_156,Kka2,kka2_1:4,P00552,1.10443,NO,156,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.696,-2.041,0.345,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.168804,0.00926998,1.10443 beta-lactamase_0_G281W,beta-lactamase_0_281,TEM-1,beta-lactamase_0,P62593,1.10447,NO,281,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.0500837,0.0406482,1.10447 beta-lactamase_0_A225H,beta-lactamase_0_225,TEM-1,beta-lactamase_0,P62593,1.10453,NO,225,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.845,-3.109,1.264,,1,T,B,0.46,-0.38,11.722,11.722,74.48,OHO,-1.39967,0.0500837,0.00465057,1.10453 beta-lactamase_0_M67V,beta-lactamase_0_67,TEM-1,beta-lactamase_0,P62593,1.10453,NO,67,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-2.231,-2.772,0.541,,0.006,G,P,0.55,-0.81,24.165,24.165,65.03,HHP,-1.502,0.0500837,0.00409753,1.10453 beta-lactamase_0_L55F,beta-lactamase_0_55,TEM-1,beta-lactamase_0,P62593,1.10455,NO,55,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.86,-2.527,0.667,,0.372,E,A,0.55,-0.36,1.967,,63.99,HHA,-2.247,0.0500837,0.00403741,1.10455 beta-lactamase_0_A84M,beta-lactamase_0_84,TEM-1,beta-lactamase_0,P62593,1.10466,NO,84,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.651,-4.707,3.056,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.0500837,0.00503822,1.10466 kka2_1:2_V80M,kka2_1:2_80,Kka2,kka2_1:2,P00552,1.10471,NO,80,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.144,-4.231,3.087,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.295029,0.00488211,1.10471 kka2_1:8_E142P,kka2_1:8_142,Kka2,kka2_1:8,P00552,1.10475,NO,142,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.221,-2.43,0.209,,0.471,H,A,1.04,0.85,2.655,,65.53,HAB,-2.08033,0.100394,0.00748883,1.10475 kka2_1:8_E142P,kka2_1:8_142,Kka2,kka2_1:8,P00552,1.10475,NO,142,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.221,-2.43,0.209,,0.471,H,A,1.04,0.85,2.655,,65.53,HAB,-2.08033,0.100394,0.00748883,1.10475 kka2_1:8_R145W,kka2_1:8_145,Kka2,kka2_1:8,P00552,1.10491,NO,145,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.804,-3.243,1.439,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.100394,0.00846663,1.10491 kka2_1:8_R145W,kka2_1:8_145,Kka2,kka2_1:8,P00552,1.10491,NO,145,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.804,-3.243,1.439,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.100394,0.00846663,1.10491 kka2_1:4_C77A,kka2_1:4_77,Kka2,kka2_1:4,P00552,1.10494,NO,77,C,A,CA,Special,Hydrophobic,5.07,6,0.93,195,121,89,-32,108.5,88.6,-19.9,-1.477,-1.773,0.296,,0.229,B,b,0.46,-0.57,2.499,,63.26,OOH,-1.55667,0.168804,0.00441216,1.10494 beta-lactamase_0_L223T,beta-lactamase_0_223,TEM-1,beta-lactamase_0,P62593,1.10496,NO,223,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.055,-2.595,1.54,,0.27,,B,0.55,0.09,1.633,,74.48,HHO,-1.35033,0.0500837,0.00372793,1.10496 kka2_1:8_E199W,kka2_1:8_199,Kka2,kka2_1:8,P00552,1.10496,NO,199,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.234,-3.699,1.465,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.100394,0.00854122,1.10496 kka2_1:8_E199W,kka2_1:8_199,Kka2,kka2_1:8,P00552,1.10496,NO,199,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.234,-3.699,1.465,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.100394,0.00854122,1.10496 kka2_1:2_V198Q,kka2_1:2_198,Kka2,kka2_1:2,P00552,1.105,NO,198,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.719,-4.058,2.339,,0.05,E,B,1.48,-0.95,1.074,,56.06,HHA,-1.88667,0.295029,0.00835002,1.105 kka2_1:8_I29D,kka2_1:8_29,Kka2,kka2_1:8,P00552,1.10501,NO,29,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.692,-3.047,1.355,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.100394,0.00619521,1.10501 kka2_1:8_I29D,kka2_1:8_29,Kka2,kka2_1:8,P00552,1.10501,NO,29,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.692,-3.047,1.355,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.100394,0.00619521,1.10501 kka2_1:4_R177P,kka2_1:4_177,Kka2,kka2_1:4,P00552,1.10503,NO,177,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.282,-4.106,1.824,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.168804,0.00768224,1.10503 kka2_1:8_E230K,kka2_1:8_230,Kka2,kka2_1:8,P00552,1.10503,NO,230,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.672,-3.648,0.976,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.100394,0.00920051,1.10503 kka2_1:8_E230K,kka2_1:8_230,Kka2,kka2_1:8,P00552,1.10503,NO,230,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.672,-3.648,0.976,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.100394,0.00920051,1.10503 kka2_1:2_T73V,kka2_1:2_73,Kka2,kka2_1:2,P00552,1.1051,NO,73,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.51,-2.513,0.003,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.295029,0.00628605,1.1051 kka2_1:8_A65T,kka2_1:8_65,Kka2,kka2_1:8,P00552,1.10511,NO,65,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.744,-2.824,1.08,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.100394,0.00709258,1.10511 kka2_1:8_A65T,kka2_1:8_65,Kka2,kka2_1:8,P00552,1.10511,NO,65,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.744,-2.824,1.08,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.100394,0.00709258,1.10511 kka2_1:2_A166S,kka2_1:2_166,Kka2,kka2_1:2,P00552,1.10519,NO,166,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.407,-1.802,-0.605,,0.534,.,B,0.46,1.03,23.175,23.175,71.59,HHO,-2.421,0.295029,0.00799912,1.10519 beta-lactamase_0_I206F,beta-lactamase_0_206,TEM-1,beta-lactamase_0,P62593,1.10521,NO,206,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-2.429,-4.165,1.736,,0.173,H,A,0.48,-0.34,3.411,,77.62,HHA,-1.805,0.0500837,0.00528934,1.10521 kka2_1:8_D154S,kka2_1:8_154,Kka2,kka2_1:8,P00552,1.10522,NO,154,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.876,-3.211,2.335,,0.457,,b,0.29,1.48,0.844,,52.65,HAP,-1.52467,0.100394,0.00292633,1.10522 kka2_1:8_D154S,kka2_1:8_154,Kka2,kka2_1:8,P00552,1.10522,NO,154,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.876,-3.211,2.335,,0.457,,b,0.29,1.48,0.844,,52.65,HAP,-1.52467,0.100394,0.00292633,1.10522 beta-lactamase_0_E108G,beta-lactamase_0_108,TEM-1,beta-lactamase_0,P62593,1.10524,NO,108,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.46,-2.454,0.994,,0.572,G,A,1.04,1.87,8.602,8.602,72.73,PAB,-1.437,0.0500837,0.00413372,1.10524 kka2_1:2_A13E,kka2_1:2_13,Kka2,kka2_1:2,P00552,1.10524,NO,13,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.248,-2.832,0.584,,0.689,G,A,0.46,0.99,,,92.05,OHH,-1.646,0.295029,0.00784241,1.10524 beta-lactamase_0_E61N,beta-lactamase_0_61,TEM-1,beta-lactamase_0,P62593,1.10525,NO,61,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.115,-2.373,0.258,,0.775,T,a,1.04,1.29,34.763,34.763,77.62,OAA,-1.92567,0.0500837,0.00440955,1.10525 beta-lactamase_0_G114I,beta-lactamase_0_114,TEM-1,beta-lactamase_0,P62593,1.10528,NO,114,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.094,-4.083,2.989,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.0500837,0.00224919,1.10528 kka2_1:4_D183H,kka2_1:4_183,Kka2,kka2_1:4,P00552,1.10528,NO,183,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.204,-4.489,3.285,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.168804,0.00426304,1.10528 beta-lactamase_2500_E210Y,beta-lactamase_2500_210,TEM-1,beta-lactamase_2500,P62593,1.1053,NO,210,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.319,-4.214,1.895,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.361275,0.00663582,1.1053 kka2_1:8_E111Q,kka2_1:8_111,Kka2,kka2_1:8,P00552,1.10538,NO,111,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.28,-2.347,0.067,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.100394,0.00746789,1.10538 kka2_1:8_E111Q,kka2_1:8_111,Kka2,kka2_1:8,P00552,1.10538,NO,111,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.28,-2.347,0.067,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.100394,0.00746789,1.10538 kka2_1:8_T72H,kka2_1:8_72,Kka2,kka2_1:8,P00552,1.1054,NO,72,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.38,-4.753,2.373,,0.784,H,A,0.22,0.29,3.603,,65.53,HPP,-2.238,0.100394,0.00750756,1.1054 kka2_1:8_T72H,kka2_1:8_72,Kka2,kka2_1:8,P00552,1.1054,NO,72,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.38,-4.753,2.373,,0.784,H,A,0.22,0.29,3.603,,65.53,HPP,-2.238,0.100394,0.00750756,1.1054 kka2_1:8_E111T,kka2_1:8_111,Kka2,kka2_1:8,P00552,1.10547,NO,111,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.28,-2.755,0.475,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.100394,0.00746789,1.10547 kka2_1:8_E111T,kka2_1:8_111,Kka2,kka2_1:8,P00552,1.10547,NO,111,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.28,-2.755,0.475,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.100394,0.00746789,1.10547 kka2_1:8_V16Q,kka2_1:8_16,Kka2,kka2_1:8,P00552,1.10548,NO,16,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-3.087,-2.664,-0.423,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.100394,0.00694011,1.10548 kka2_1:8_V16Q,kka2_1:8_16,Kka2,kka2_1:8,P00552,1.10548,NO,16,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-3.087,-2.664,-0.423,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.100394,0.00694011,1.10548 kka2_1:2_P76K,kka2_1:2_76,Kka2,kka2_1:2,P00552,1.10551,NO,76,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.449,-3.635,2.186,,0.331,.,B,0.52,-0.41,0.345,,63.64,HOO,-1.662,0.295029,0.00625685,1.10551 kka2_1:2_F264Y,kka2_1:2_264,Kka2,kka2_1:2,P00552,1.10552,NO,264,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.02,-2.016,0.996,,0.296,.,?,0.58,0.02,2.303,,71.59,HHNA,-0.9655,0.295029,,1.10552 kka2_1:8_T146W,kka2_1:8_146,Kka2,kka2_1:8,P00552,1.10554,NO,146,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.978,-5.546,2.568,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.100394,0.00606474,1.10554 kka2_1:8_T146W,kka2_1:8_146,Kka2,kka2_1:8,P00552,1.10554,NO,146,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.978,-5.546,2.568,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.100394,0.00606474,1.10554 PSD95pdz3_I314Y,PSD95pdz3_314,PSD95pdz3,PSD95pdz3,P31016,1.10562,NO,314,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.628,-3.714,2.086,5.39919,,,,,15.7775,0.397,,81.35,BHH,-1.61167,0.0758425,0.0012606,1.10562 beta-lactamase_39_V106A,beta-lactamase_39_106,TEM-1,beta-lactamase_39,P62593,1.10565,NO,106,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.218,-3.084,1.866,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.0495842,0.00304168,1.10565 beta-lactamase_0_D33W,beta-lactamase_0_33,TEM-1,beta-lactamase_0,P62593,1.10569,NO,33,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.321,-5.495,3.174,,0.366,H,A,0.75,0.33,12.514,12.514,77.62,BAH,-2.12133,0.0500837,0.00435556,1.10569 PSD95pdz3_R312H,PSD95pdz3_312,PSD95pdz3,PSD95pdz3,P31016,1.1057,NO,312,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.582,-3.912,2.33,5.76826,,,,,12.2409,,,,OBB,-1.46667,0.0758425,0.00196255,1.1057 kka2_1:4_D134N,kka2_1:4_134,Kka2,kka2_1:4,P00552,1.10571,NO,134,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.969,-2.658,1.689,,0.421,B,B,0.75,0.31,0.733,,49.62,HAB,-1.057,0.168804,0.00270812,1.10571 kka2_1:4_I246V,kka2_1:4_246,Kka2,kka2_1:4,P00552,1.10572,NO,246,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-2.008,-2.046,0.038,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.168804,0.0139479,1.10572 beta-lactamase_0_F58S,beta-lactamase_0_58,TEM-1,beta-lactamase_0,P62593,1.10576,NO,58,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-2.914,-2.895,-0.019,,0.266,E,B,0.58,-0.07,24.637,24.637,77.62,PHB,-2.059,0.0500837,0.00523369,1.10576 WW_domain_D194H,WW_domain_194,Yap65,WW_domain,P46937,1.10578,NO,194,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.536,-4.308,2.772,5.95614,,,,,,1.948,,74.4,HAP,-1.78933,0.153962,0.00483742,1.10578 kka2_1:2_Q4I,kka2_1:2_4,Kka2,kka2_1:2,P00552,1.10583,NO,4,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.361,-3.887,1.526,,,,,,,2.026,,71.59,APA,-1.95533,0.295029,0.00239179,1.10583 PSD95pdz3_V315Q,PSD95pdz3_315,PSD95pdz3,PSD95pdz3,P31016,1.10583,NO,315,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.625,-4.024,2.399,5.52024,,,,,18.4557,4.054,,81.35,HHH,-1.62767,0.0758425,0.00153536,1.10583 kka2_1:8_D180S,kka2_1:8_180,Kka2,kka2_1:8,P00552,1.10585,NO,180,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.416,-2.79,0.374,,1.03,S,a,0.75,1.5,14.668,14.668,71.59,OAO,-2.02933,0.100394,0.00756412,1.10585 kka2_1:8_D180S,kka2_1:8_180,Kka2,kka2_1:8,P00552,1.10585,NO,180,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.416,-2.79,0.374,,1.03,S,a,0.75,1.5,14.668,14.668,71.59,OAO,-2.02933,0.100394,0.00756412,1.10585 kka2_1:4_R18C,kka2_1:4_18,Kka2,kka2_1:4,P00552,1.10586,NO,18,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.055,-5.174,3.119,,0.474,T,A,1.2,0.54,8.405,8.405,71.59,ABH,-1.821,0.168804,0.00724065,1.10586 kka2_1:8_A41Y,kka2_1:8_41,Kka2,kka2_1:8,P00552,1.10586,NO,41,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.879,-4.263,2.384,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.100394,0.00543332,1.10586 kka2_1:8_A41Y,kka2_1:8_41,Kka2,kka2_1:8,P00552,1.10586,NO,41,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.879,-4.263,2.384,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.100394,0.00543332,1.10586 beta-lactamase_0_G141Q,beta-lactamase_0_141,TEM-1,beta-lactamase_0,P62593,1.10591,NO,141,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.828,-3.982,3.154,,0.575,T,l,0.29,-0.28,0.722,,64.69,HOO,-1.08933,0.0500837,0.0012419,1.10591 kka2_1:4_A248S,kka2_1:4_248,Kka2,kka2_1:4,P00552,1.10591,NO,248,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.124,-2.844,0.72,,0.825,S,b,0.46,0.46,,,92.05,HHO,-2.15,0.168804,0.0125484,1.10591 kka2_1:4_A247C,kka2_1:4_247,Kka2,kka2_1:4,P00552,1.10595,NO,247,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.459,-5.101,2.642,,1.01,S,A,0.46,0.65,,,92.05,HHH,-2.197,0.168804,0.0102428,1.10595 kka2_1:4_T85S,kka2_1:4_85,Kka2,kka2_1:4,P00552,1.10595,NO,85,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.165,-2.241,0.076,,0.576,E,B,0.22,1.39,1.853,,71.59,HPA,-2.10133,0.168804,0.00634493,1.10595 beta-lactamase_0_L188M,beta-lactamase_0_188,TEM-1,beta-lactamase_0,P62593,1.10597,NO,188,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.166,-2.706,1.54,,,H,A,0.55,-0.3,2.739,,60.14,PHB,-1.47033,0.0500837,0.00295687,1.10597 kka2_1:4_L259I,kka2_1:4_259,Kka2,kka2_1:4,P00552,1.10608,NO,259,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.088,-3.1,2.012,,0.036,H,A,0.55,-0.15,2.183,,48.48,BHH,-1.15167,0.168804,0.0206964,1.10608 kka2_1:8_R143C,kka2_1:8_143,Kka2,kka2_1:8,P00552,1.10612,NO,143,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.525,-5.079,2.554,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.100394,0.00662247,1.10612 kka2_1:8_R143C,kka2_1:8_143,Kka2,kka2_1:8,P00552,1.10612,NO,143,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.525,-5.079,2.554,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.100394,0.00662247,1.10612 kka2_1:4_Q136K,kka2_1:4_136,Kka2,kka2_1:4,P00552,1.10618,NO,136,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-3.021,-3.273,0.252,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.168804,0.00624149,1.10618 kka2_1:4_A176S,kka2_1:4_176,Kka2,kka2_1:4,P00552,1.10622,NO,176,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.621,-1.88,0.259,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.168804,0.0083587,1.10622 beta-lactamase_0_I244Y,beta-lactamase_0_244,TEM-1,beta-lactamase_0,P62593,1.10625,NO,244,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.555,-4.031,2.476,,,E,B,0.48,-0.84,1.241,,77.62,OHH,-1.385,0.0500837,0.00605379,1.10625 kka2_1:8_E149I,kka2_1:8_149,Kka2,kka2_1:8,P00552,1.10629,NO,149,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.994,-3.262,1.268,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.100394,0.00803343,1.10629 kka2_1:8_E149I,kka2_1:8_149,Kka2,kka2_1:8,P00552,1.10629,NO,149,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.994,-3.262,1.268,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.100394,0.00803343,1.10629 PSD95pdz3_I316M,PSD95pdz3_316,PSD95pdz3,PSD95pdz3,P31016,1.1063,NO,316,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.63,-3.712,2.082,5.46166,,,,,19.005,,,,HHB,-1.62733,0.0758425,0.00112762,1.1063 PSD95pdz3_R312N,PSD95pdz3_312,PSD95pdz3,PSD95pdz3,P31016,1.10636,NO,312,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.582,-3.13,1.548,5.76826,,,,,12.2409,,,,OBB,-1.46667,0.0758425,0.00196255,1.10636 beta-lactamase_39_V157G,beta-lactamase_39_157,TEM-1,beta-lactamase_39,P62593,1.10643,NO,157,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.751,-3.625,1.874,,0.308,S,a,0.44,-0.75,10.364,10.364,69.58,BHP,-2.00767,0.0495842,0.00506849,1.10643 kka2_1:2_M178V,kka2_1:2_178,Kka2,kka2_1:2,P00552,1.10651,NO,178,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-3.206,-2.808,-0.398,,0.554,.,b,0.55,0.68,3.152,,71.59,BHO,-2.154,0.295029,0.00717253,1.10651 kka2_1:2_V75C,kka2_1:2_75,Kka2,kka2_1:2,P00552,1.10663,NO,75,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-2.06,-4.904,2.844,,0.042,.,B,0.44,-0.2,2.815,,71.59,OHO,-1.563,0.295029,0.00693733,1.10663 kka2_1:4_L165D,kka2_1:4_165,Kka2,kka2_1:4,P00552,1.10664,NO,165,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-2.453,-3.848,1.395,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.168804,0.00801161,1.10664 kka2_1:4_D90H,kka2_1:4_90,Kka2,kka2_1:4,P00552,1.10665,NO,90,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.459,-2.113,-0.346,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.168804,0.00583842,1.10665 beta-lactamase_0_R242T,beta-lactamase_0_242,TEM-1,beta-lactamase_0,P62593,1.10667,NO,242,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.0500837,0.00452879,1.10667 kka2_1:8_R44K,kka2_1:8_44,Kka2,kka2_1:8,P00552,1.10667,NO,44,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.062,-2.763,0.701,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.100394,0.00745043,1.10667 kka2_1:8_R44K,kka2_1:8_44,Kka2,kka2_1:8,P00552,1.10667,NO,44,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.062,-2.763,0.701,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.100394,0.00745043,1.10667 kka2_1:8_Q136L,kka2_1:8_136,Kka2,kka2_1:8,P00552,1.10681,NO,136,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-3.021,-3.571,0.55,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.100394,0.00624149,1.10681 kka2_1:8_Q136L,kka2_1:8_136,Kka2,kka2_1:8,P00552,1.10681,NO,136,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-3.021,-3.571,0.55,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.100394,0.00624149,1.10681 kka2_1:8_E169Q,kka2_1:8_169,Kka2,kka2_1:8,P00552,1.10684,NO,169,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.996,-2.511,0.515,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.100394,0.00730086,1.10684 kka2_1:8_E169Q,kka2_1:8_169,Kka2,kka2_1:8,P00552,1.10684,NO,169,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.996,-2.511,0.515,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.100394,0.00730086,1.10684 kka2_1:2_T130A,kka2_1:2_130,Kka2,kka2_1:2,P00552,1.10688,NO,130,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.392,-1.951,-0.441,,0.561,G,A,0.22,0.77,0.5,,92.05,HPO,-1.62633,0.295029,0.00804204,1.10688 kka2_1:2_D52I,kka2_1:2_52,Kka2,kka2_1:2,P00552,1.10689,NO,52,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.271,-4.062,1.791,,0.22,E,B,0.75,0.8,1.123,,71.59,PAH,-2.38367,0.295029,0.00175694,1.10689 beta-lactamase_0_K109R,beta-lactamase_0_109,TEM-1,beta-lactamase_0,P62593,1.10691,NO,109,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.734,-2.595,0.861,,0.787,G,A,2.34,2.21,15.473,15.473,72.73,ABB,-1.63333,0.0500837,0.00462493,1.10691 kka2_1:1_S11A,kka2_1:1_11,Kka2,kka2_1:1,P00552,1.107,NO,11,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.322,-2.34,0.018,,0.408,,B,0.77,1.64,2.054,,92.05,OPO,-1.69867,0.520039,0.00381691,1.107 kka2_1:8_S105M,kka2_1:8_105,Kka2,kka2_1:8,P00552,1.10701,NO,105,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.945,-4.741,2.796,,0.056,S,B,0.27,-1.04,2.115,,65.53,PPB,-2.17033,0.100394,0.00847233,1.10701 kka2_1:8_S105M,kka2_1:8_105,Kka2,kka2_1:8,P00552,1.10701,NO,105,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.945,-4.741,2.796,,0.056,S,B,0.27,-1.04,2.115,,65.53,PPB,-2.17033,0.100394,0.00847233,1.10701 kka2_1:8_V46A,kka2_1:8_46,Kka2,kka2_1:8,P00552,1.10705,NO,46,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-2.62,-2.194,-0.426,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.100394,0.00631301,1.10705 kka2_1:8_V46A,kka2_1:8_46,Kka2,kka2_1:8,P00552,1.10705,NO,46,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-2.62,-2.194,-0.426,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.100394,0.00631301,1.10705 kka2_1:8_T187C,kka2_1:8_187,Kka2,kka2_1:8,P00552,1.10706,NO,187,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.273,-2.642,1.369,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.100394,0.00693073,1.10706 kka2_1:8_T187C,kka2_1:8_187,Kka2,kka2_1:8,P00552,1.10706,NO,187,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.273,-2.642,1.369,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.100394,0.00693073,1.10706 kka2_1:8_W24R,kka2_1:8_24,Kka2,kka2_1:8,P00552,1.10717,NO,24,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-1.779,-4.308,2.529,,0.477,E,B,1.51,-0.21,2.503,,56.06,AHH,-2.24467,0.100394,0.00631564,1.10717 kka2_1:8_W24R,kka2_1:8_24,Kka2,kka2_1:8,P00552,1.10717,NO,24,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,-1.779,-4.308,2.529,,0.477,E,B,1.51,-0.21,2.503,,56.06,AHH,-2.24467,0.100394,0.00631564,1.10717 kka2_1:2_T72D,kka2_1:2_72,Kka2,kka2_1:2,P00552,1.10732,NO,72,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.38,-3.042,0.662,,0.784,H,A,0.82,0.29,6.463,,65.53,HPP,-2.238,0.295029,0.00750756,1.10732 kka2_1:8_D118K,kka2_1:8_118,Kka2,kka2_1:8,P00552,1.10734,NO,118,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.07,-2.906,0.836,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.100394,0.0067852,1.10734 kka2_1:8_D118K,kka2_1:8_118,Kka2,kka2_1:8,P00552,1.10734,NO,118,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.07,-2.906,0.836,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.100394,0.0067852,1.10734 kka2_1:4_L47W,kka2_1:4_47,Kka2,kka2_1:4,P00552,1.10735,NO,47,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.265,-5.21,3.945,,0.139,E,B,0.55,-0.86,2.369,,63.26,HHH,-1.77933,0.168804,0.00509386,1.10735 kka2_1:8_A35M,kka2_1:8_35,Kka2,kka2_1:8,P00552,1.10735,NO,35,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.127,-3.59,1.463,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.100394,0.00630016,1.10735 kka2_1:8_A35M,kka2_1:8_35,Kka2,kka2_1:8,P00552,1.10735,NO,35,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.127,-3.59,1.463,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.100394,0.00630016,1.10735 gb1_A250C,gb1_250,gb1,gb1,P06654,1.10738,NO,250,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.713,-4.701,2.988,,,,,,,3.465,,45.54,HHP,-1.74867,0.177985,0.00332003,1.10738 kka2_1:8_Q61L,kka2_1:8_61,Kka2,kka2_1:8,P00552,1.10749,NO,61,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.982,-2.984,0.002,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.100394,0.00612092,1.10749 kka2_1:8_Q61L,kka2_1:8_61,Kka2,kka2_1:8,P00552,1.10749,NO,61,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.982,-2.984,0.002,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.100394,0.00612092,1.10749 kka2_1:8_L81K,kka2_1:8_81,Kka2,kka2_1:8,P00552,1.10759,NO,81,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.427,-3.851,2.424,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.100394,0.00805839,1.10759 kka2_1:8_L81K,kka2_1:8_81,Kka2,kka2_1:8,P00552,1.10759,NO,81,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.427,-3.851,2.424,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.100394,0.00805839,1.10759 PSD95pdz3_I338T,PSD95pdz3_338,PSD95pdz3,PSD95pdz3,P31016,1.10759,NO,338,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.63,-3.103,1.473,5.45113,,,,,13.0087,,,,HHP,-1.55767,0.0758425,0.000862587,1.10759 kka2_1:4_D154M,kka2_1:4_154,Kka2,kka2_1:4,P00552,1.10762,NO,154,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.876,-4.959,4.083,,0.457,,b,0.29,1.48,15.641,15.641,52.65,HAP,-1.52467,0.168804,0.00292633,1.10762 kka2_1:2_D118Q,kka2_1:2_118,Kka2,kka2_1:2,P00552,1.10769,NO,118,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.07,-2.739,0.669,,0.61,H,A,0.75,-0.05,2.237,,64.39,HAH,-1.32367,0.295029,0.0067852,1.10769 beta-lactamase_39_L100W,beta-lactamase_39_100,TEM-1,beta-lactamase_39,P62593,1.10772,NO,100,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.218,-5.168,3.95,,0.343,,B,0.55,0.13,8.311,,63.29,AHH,-1.23467,0.0495842,0.00413885,1.10772 kka2_1:8_D90E,kka2_1:8_90,Kka2,kka2_1:8,P00552,1.10775,NO,90,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.459,-2.578,0.119,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.100394,0.00583842,1.10775 kka2_1:8_D90E,kka2_1:8_90,Kka2,kka2_1:8,P00552,1.10775,NO,90,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.459,-2.578,0.119,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.100394,0.00583842,1.10775 kka2_1:8_F171L,kka2_1:8_171,Kka2,kka2_1:8,P00552,1.10775,NO,171,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.326,-1.818,0.492,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.100394,0.00821426,1.10775 kka2_1:8_F171L,kka2_1:8_171,Kka2,kka2_1:8,P00552,1.10775,NO,171,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.326,-1.818,0.492,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.100394,0.00821426,1.10775 kka2_1:2_G21D,kka2_1:2_21,Kka2,kka2_1:2,P00552,1.10782,NO,21,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.368,-1.988,0.62,,0.586,T,l,0.29,-0.75,2.026,,71.59,HOH,-2.10167,0.295029,0.00709648,1.10782 kka2_1:8_Q219V,kka2_1:8_219,Kka2,kka2_1:8,P00552,1.10782,NO,219,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-0.93,-3.601,2.671,,0.088,H,A,0.4,-0.85,0.897,,50,HPA,-1.05167,0.100394,0.00237913,1.10782 kka2_1:8_Q219V,kka2_1:8_219,Kka2,kka2_1:8,P00552,1.10782,NO,219,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-0.93,-3.601,2.671,,0.088,H,A,0.4,-0.85,0.897,,50,HPA,-1.05167,0.100394,0.00237913,1.10782 beta-lactamase_0_D155V,beta-lactamase_0_155,TEM-1,beta-lactamase_0,P62593,1.10783,NO,155,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.889,-3.778,2.889,,0.049,,B,0.75,-0.9,16.833,16.833,64.69,OAB,-1.62267,0.0500837,0.00135315,1.10783 kka2_1:4_A166V,kka2_1:4_166,Kka2,kka2_1:4,P00552,1.10784,NO,166,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.407,-3.015,0.608,,0.534,.,B,0.46,1.03,,,71.59,HHO,-2.421,0.168804,0.00799912,1.10784 beta-lactamase_0_K213C,beta-lactamase_0_213,TEM-1,beta-lactamase_0,P62593,1.10797,NO,213,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.81,-5.208,3.398,,0.67,,A,2.34,0.29,3.015,,67.83,ABH,-1.57767,0.0500837,0.00610411,1.10797 kka2_1:4_Q136M,kka2_1:4_136,Kka2,kka2_1:4,P00552,1.10797,NO,136,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-3.021,-4.715,1.694,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.168804,0.00624149,1.10797 kka2_1:4_Q42C,kka2_1:4_42,Kka2,kka2_1:4,P00552,1.10803,NO,42,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.907,-5.227,2.32,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.168804,0.00679212,1.10803 beta-lactamase_0_R41Y,beta-lactamase_0_41,TEM-1,beta-lactamase_0,P62593,1.10808,NO,41,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-0.942,-4.188,3.246,,0.321,E,B,1.2,-0.07,2.68,,65.03,HBH,-1.30267,0.0500837,0.00123327,1.10808 PSD95pdz3_V315Y,PSD95pdz3_315,PSD95pdz3,PSD95pdz3,P31016,1.10808,NO,315,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.625,-3.778,2.153,5.52024,,,,,18.4557,4.054,,81.35,HHH,-1.62767,0.0758425,0.00153536,1.10808 kka2_1:8_H8Y,kka2_1:8_8,Kka2,kka2_1:8,P00552,1.1081,NO,8,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-2.759,-3.943,1.184,,,,,,,,,71.59,HBH,-2.25467,0.100394,0.00256422,1.1081 kka2_1:8_H8Y,kka2_1:8_8,Kka2,kka2_1:8,P00552,1.1081,NO,8,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-2.759,-3.943,1.184,,,,,,,,,71.59,HBH,-2.25467,0.100394,0.00256422,1.1081 beta-lactamase_0_T263D,beta-lactamase_0_263,TEM-1,beta-lactamase_0,P62593,1.10811,NO,263,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.0500837,0.0110582,1.10811 kka2_1:4_E142N,kka2_1:4_142,Kka2,kka2_1:4,P00552,1.10811,NO,142,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.221,-3.851,1.63,,0.471,H,A,1.52,0.85,3.693,,65.53,HAB,-2.08033,0.168804,0.00748883,1.10811 kka2_1:2_L60M,kka2_1:2_60,Kka2,kka2_1:2,P00552,1.10816,NO,60,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.997,-2.995,1.998,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.295029,0.00262176,1.10816 PSD95pdz3_S361Y,PSD95pdz3_361,PSD95pdz3,PSD95pdz3,P31016,1.10816,NO,361,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.519,-3.844,2.325,4.8722,,,,,16.4533,,,,HPH,-1.47167,0.0758425,0.00055296,1.10816 beta-lactamase_0_N152I,beta-lactamase_0_152,TEM-1,beta-lactamase_0,P62593,1.10823,NO,152,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-2.757,-3.192,0.435,,0.863,H,A,0.61,0.92,2.151,,77.62,BPH,-2.97,0.0500837,0.00471429,1.10823 kka2_1:4_E111S,kka2_1:4_111,Kka2,kka2_1:4,P00552,1.10831,NO,111,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.28,-2.706,0.426,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.168804,0.00746789,1.10831 kka2_1:8_L53Y,kka2_1:8_53,Kka2,kka2_1:8,P00552,1.10831,NO,53,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-2.681,-4.449,1.768,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.100394,0.00671168,1.10831 kka2_1:8_L53Y,kka2_1:8_53,Kka2,kka2_1:8,P00552,1.10831,NO,53,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-2.681,-4.449,1.768,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.100394,0.00671168,1.10831 beta-lactamase_0_A77N,beta-lactamase_0_77,TEM-1,beta-lactamase_0,P62593,1.1084,NO,77,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.234,-3.844,2.61,,0.039,H,A,0.46,-0.56,2.591,,64.34,OHH,-1.294,0.0500837,0.00282362,1.1084 WW_domain_D194W,WW_domain_194,Yap65,WW_domain,P46937,1.10848,NO,194,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.536,-5.393,3.857,5.95614,,,,,,1.948,,74.4,HAP,-1.78933,0.153962,0.00483742,1.10848 kka2_1:8_V84K,kka2_1:8_84,Kka2,kka2_1:8,P00552,1.10854,NO,84,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-2.279,-3.653,1.374,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.100394,0.00724019,1.10854 kka2_1:8_V84K,kka2_1:8_84,Kka2,kka2_1:8,P00552,1.10854,NO,84,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-2.279,-3.653,1.374,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.100394,0.00724019,1.10854 PSD95pdz3_V315S,PSD95pdz3_315,PSD95pdz3,PSD95pdz3,P31016,1.10856,NO,315,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.625,-3.451,1.826,5.52024,,,,,18.4557,4.054,,81.35,HHH,-1.62767,0.0758425,0.00153536,1.10856 kka2_1:2_L165K,kka2_1:2_165,Kka2,kka2_1:2,P00552,1.10864,NO,165,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-2.453,-2.336,-0.117,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.295029,0.00801161,1.10864 kka2_1:8_A229K,kka2_1:8_229,Kka2,kka2_1:8,P00552,1.10866,NO,229,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.739,-3.497,1.758,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.100394,0.00942138,1.10866 kka2_1:8_A229K,kka2_1:8_229,Kka2,kka2_1:8,P00552,1.10866,NO,229,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.739,-3.497,1.758,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.100394,0.00942138,1.10866 kka2_1:8_T51C,kka2_1:8_51,Kka2,kka2_1:8,P00552,1.10866,NO,51,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.199,-3.244,1.045,,0.05,E,B,0.82,-0.05,5.399,,63.64,BPA,-1.76767,0.100394,0.00628861,1.10866 kka2_1:8_T51C,kka2_1:8_51,Kka2,kka2_1:8,P00552,1.10866,NO,51,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.199,-3.244,1.045,,0.05,E,B,0.82,-0.05,5.399,,63.64,BPA,-1.76767,0.100394,0.00628861,1.10866 kka2_1:8_R18E,kka2_1:8_18,Kka2,kka2_1:8,P00552,1.10878,NO,18,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.055,-2.876,0.821,,0.474,T,A,1.2,0.54,19.629,19.629,71.59,ABH,-1.821,0.100394,0.00724065,1.10878 kka2_1:8_R18E,kka2_1:8_18,Kka2,kka2_1:8,P00552,1.10878,NO,18,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.055,-2.876,0.821,,0.474,T,A,1.2,0.54,19.629,19.629,71.59,ABH,-1.821,0.100394,0.00724065,1.10878 kka2_1:4_D238Y,kka2_1:4_238,Kka2,kka2_1:4,P00552,1.10885,NO,238,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.83,-4.447,1.617,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.168804,0.0113863,1.10885 kka2_1:4_A71M,kka2_1:4_71,Kka2,kka2_1:4,P00552,1.10887,NO,71,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.824,-3.582,1.758,,0.553,H,A,0.46,0.08,5.76,,64.39,HHP,-1.74033,0.168804,0.00727707,1.10887 beta-lactamase_0_G240F,beta-lactamase_0_240,TEM-1,beta-lactamase_0,P62593,1.1089,NO,240,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.0500837,0.00591201,1.1089 kka2_1:8_H106A,kka2_1:8_106,Kka2,kka2_1:8,P00552,1.1089,NO,106,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-3.13,-2.399,-0.731,,1.065,,a,0.87,-0.95,15.956,15.956,71.59,PBH,-2.10433,0.100394,0.00730778,1.1089 kka2_1:8_H106A,kka2_1:8_106,Kka2,kka2_1:8,P00552,1.1089,NO,106,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-3.13,-2.399,-0.731,,1.065,,a,0.87,-0.95,15.956,15.956,71.59,PBH,-2.10433,0.100394,0.00730778,1.1089 beta-lactamase_0_L188S,beta-lactamase_0_188,TEM-1,beta-lactamase_0,P62593,1.10898,NO,188,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.166,-3.587,2.421,,,H,A,0.55,-0.3,2.739,,60.14,PHB,-1.47033,0.0500837,0.00295687,1.10898 beta-lactamase_0_P60G,beta-lactamase_0_60,TEM-1,beta-lactamase_0,P62593,1.109,NO,60,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-2.469,-2.095,-0.374,,0.256,T,A,0.52,-0.56,3.653,,77.62,BOA,-1.97633,0.0500837,0.00521318,1.109 beta-lactamase_0_I285P,beta-lactamase_0_285,TEM-1,beta-lactamase_0,P62593,1.10907,NO,285,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.0500837,0.101555,1.10907 beta-lactamase_0_S221M,beta-lactamase_0_221,TEM-1,beta-lactamase_0,P62593,1.10907,NO,221,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.754,-4.595,2.841,,0.624,H,A,0.27,-0.2,2.914,,74.48,BPH,-1.59967,0.0500837,0.0046094,1.10907 beta-lactamase_0_P105Y,beta-lactamase_0_105,TEM-1,beta-lactamase_0,P62593,1.10914,NO,105,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.813,-4.385,3.572,,0.226,T,A,0.52,0.8,3.48,,63.29,POH,-1.01533,0.0500837,0.0011981,1.10914 beta-lactamase_0_G90W,beta-lactamase_0_90,TEM-1,beta-lactamase_0,P62593,1.10926,NO,90,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-2.091,-5.515,3.424,,0.598,T,A,0.29,0.32,2.04,,77.62,HOB,-1.52633,0.0500837,0.00490273,1.10926 beta-lactamase_0_R92H,beta-lactamase_0_92,TEM-1,beta-lactamase_0,P62593,1.10927,NO,92,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.718,-4.618,2.9,,0.479,E,B,1.2,1.36,2.331,,65.38,BBH,-1.50367,0.0500837,0.00429626,1.10927 kka2_1:4_A35S,kka2_1:4_35,Kka2,kka2_1:4,P00552,1.10928,NO,35,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.127,-2.197,0.07,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.168804,0.00630016,1.10928 beta-lactamase_0_F149L,beta-lactamase_0_149,TEM-1,beta-lactamase_0,P62593,1.10941,NO,149,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.299,-3.137,1.838,,0.195,H,A,0.58,0.11,3.518,,63.99,HHH,-1.46067,0.0500837,0.00418462,1.10941 kka2_1:4_H139Q,kka2_1:4_139,Kka2,kka2_1:4,P00552,1.10943,NO,139,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-2.809,-2.861,0.052,,0.471,H,A,0.17,0.68,12.761,12.761,63.64,BBB,-2.22,0.168804,0.00734779,1.10943 beta-lactamase_0_D271T,beta-lactamase_0_271,TEM-1,beta-lactamase_0,P62593,1.10944,NO,271,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.0500837,0.00752082,1.10944 kka2_1:8_T72E,kka2_1:8_72,Kka2,kka2_1:8,P00552,1.10944,NO,72,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.38,-2.356,-0.024,,0.784,H,A,0.22,0.29,3.603,,65.53,HPP,-2.238,0.100394,0.00750756,1.10944 kka2_1:8_T72E,kka2_1:8_72,Kka2,kka2_1:8,P00552,1.10944,NO,72,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.38,-2.356,-0.024,,0.784,H,A,0.22,0.29,3.603,,65.53,HPP,-2.238,0.100394,0.00750756,1.10944 kka2_1:8_D118I,kka2_1:8_118,Kka2,kka2_1:8,P00552,1.10952,NO,118,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.07,-3.314,1.244,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.100394,0.0067852,1.10952 kka2_1:8_D118I,kka2_1:8_118,Kka2,kka2_1:8,P00552,1.10952,NO,118,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.07,-3.314,1.244,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.100394,0.0067852,1.10952 kka2_1:2_E17R,kka2_1:2_17,Kka2,kka2_1:2,P00552,1.10957,NO,17,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.154,-2.815,0.661,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.295029,0.00688738,1.10957 kka2_1:4_E142K,kka2_1:4_142,Kka2,kka2_1:4,P00552,1.10959,NO,142,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.221,-3.543,1.322,,0.471,H,A,1.52,0.85,3.693,,65.53,HAB,-2.08033,0.168804,0.00748883,1.10959 PSD95pdz3_I314A,PSD95pdz3_314,PSD95pdz3,PSD95pdz3,P31016,1.1096,NO,314,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.628,-2.758,1.13,5.39919,,,,,15.7775,0.397,,81.35,BHH,-1.61167,0.0758425,0.0012606,1.1096 kka2_1:8_L103F,kka2_1:8_103,Kka2,kka2_1:8,P00552,1.10961,NO,103,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-2.362,-4.185,1.823,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.100394,0.00574792,1.10961 kka2_1:8_L103F,kka2_1:8_103,Kka2,kka2_1:8,P00552,1.10961,NO,103,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-2.362,-4.185,1.823,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.100394,0.00574792,1.10961 kka2_1:8_A168V,kka2_1:8_168,Kka2,kka2_1:8,P00552,1.10969,NO,168,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.989,-3.131,1.142,,0.67,H,A,0.46,0.15,11.329,11.329,64.39,OHA,-2.12933,0.100394,0.00806773,1.10969 kka2_1:8_A168V,kka2_1:8_168,Kka2,kka2_1:8,P00552,1.10969,NO,168,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.989,-3.131,1.142,,0.67,H,A,0.46,0.15,11.329,11.329,64.39,OHA,-2.12933,0.100394,0.00806773,1.10969 beta-lactamase_0_G234T,beta-lactamase_0_234,TEM-1,beta-lactamase_0,P62593,1.10971,NO,234,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.62,-3.646,3.026,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.0500837,0.000889577,1.10971 kka2_1:8_H8V,kka2_1:8_8,Kka2,kka2_1:8,P00552,1.10972,NO,8,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-2.759,-3.205,0.446,,,,,,,,,71.59,HBH,-2.25467,0.100394,0.00256422,1.10972 kka2_1:8_H8V,kka2_1:8_8,Kka2,kka2_1:8,P00552,1.10972,NO,8,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-2.759,-3.205,0.446,,,,,,,,,71.59,HBH,-2.25467,0.100394,0.00256422,1.10972 beta-lactamase_0_S201Y,beta-lactamase_0_201,TEM-1,beta-lactamase_0,P62593,1.10973,NO,201,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.183,-4.222,3.039,,0.064,H,A,0.27,-0.07,3.54,,64.69,HPB,-1.451,0.0500837,0.00198815,1.10973 kka2_1:8_A110R,kka2_1:8_110,Kka2,kka2_1:8,P00552,1.10973,NO,110,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.064,-3.093,1.029,,0.175,H,A,1.04,-1.19,11.413,11.413,71.59,OHA,-1.91867,0.100394,0.00759851,1.10973 kka2_1:8_A110R,kka2_1:8_110,Kka2,kka2_1:8,P00552,1.10973,NO,110,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.064,-3.093,1.029,,0.175,H,A,1.04,-1.19,11.413,11.413,71.59,OHA,-1.91867,0.100394,0.00759851,1.10973 beta-lactamase_39_A211I,beta-lactamase_39_211,TEM-1,beta-lactamase_39,P62593,1.10979,NO,211,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.896,-4.033,2.137,,0.369,T,A,0.46,-0.69,1.419,,77.62,AHA,-1.94633,0.0495842,0.00648183,1.10979 kka2_1:8_A172E,kka2_1:8_172,Kka2,kka2_1:8,P00552,1.10979,NO,172,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.757,-2.527,0.77,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.100394,0.0079265,1.10979 kka2_1:8_A172E,kka2_1:8_172,Kka2,kka2_1:8,P00552,1.10979,NO,172,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.757,-2.527,0.77,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.100394,0.0079265,1.10979 PSD95pdz3_I316Q,PSD95pdz3_316,PSD95pdz3,PSD95pdz3,P31016,1.1098,NO,316,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.63,-4.031,2.401,5.46166,,,,,19.005,,,,HHB,-1.62733,0.0758425,0.00112762,1.1098 kka2_1:8_L102V,kka2_1:8_102,Kka2,kka2_1:8,P00552,1.10984,NO,102,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.804,-2.905,2.101,,,T,A,1.59,-1.17,0.97,,42.42,AHH,-1.398,0.100394,0.00201332,1.10984 kka2_1:8_L102V,kka2_1:8_102,Kka2,kka2_1:8,P00552,1.10984,NO,102,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.804,-2.905,2.101,,,T,A,1.59,-1.17,0.97,,42.42,AHH,-1.398,0.100394,0.00201332,1.10984 kka2_1:4_L7F,kka2_1:4_7,Kka2,kka2_1:4,P00552,1.10993,NO,7,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.926,-3.787,1.861,,,,,,,3.012,,71.59,OHB,-2.12333,0.168804,0.00269456,1.10993 kka2_1:8_G21D,kka2_1:8_21,Kka2,kka2_1:8,P00552,1.11,NO,21,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.368,-1.988,0.62,,0.586,T,l,0.29,-0.75,4.889,,71.59,HOH,-2.10167,0.100394,0.00709648,1.11 kka2_1:8_G21D,kka2_1:8_21,Kka2,kka2_1:8,P00552,1.11,NO,21,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.368,-1.988,0.62,,0.586,T,l,0.29,-0.75,4.889,,71.59,HOH,-2.10167,0.100394,0.00709648,1.11 beta-lactamase_0_D212I,beta-lactamase_0_212,TEM-1,beta-lactamase_0,P62593,1.11003,NO,212,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.624,-3.045,1.421,,0.037,,b,0.75,-0.58,3.34,,74.48,HAB,-1.77667,0.0500837,0.00644302,1.11003 beta-lactamase_0_F58E,beta-lactamase_0_58,TEM-1,beta-lactamase_0,P62593,1.11003,NO,58,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-2.914,-3.579,0.665,,0.266,E,B,0.58,-0.07,24.637,24.637,77.62,PHB,-2.059,0.0500837,0.00523369,1.11003 beta-lactamase_0_H110C,beta-lactamase_0_110,TEM-1,beta-lactamase_0,P62593,1.11009,NO,110,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-1.706,-5.217,3.511,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.0500837,0.00441499,1.11009 kka2_1:8_L243I,kka2_1:8_243,Kka2,kka2_1:8,P00552,1.11009,NO,243,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-2.651,-3.227,0.576,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.100394,0.00884927,1.11009 kka2_1:8_L243I,kka2_1:8_243,Kka2,kka2_1:8,P00552,1.11009,NO,243,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-2.651,-3.227,0.576,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.100394,0.00884927,1.11009 beta-lactamase_0_V72P,beta-lactamase_0_72,TEM-1,beta-lactamase_0,P62593,1.11011,NO,72,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.658,-2.442,0.784,,,H,A,0.44,-1.03,2.964,,65.73,BHH,-1.32167,0.0500837,0.00501194,1.11011 kka2_1:8_S40G,kka2_1:8_40,Kka2,kka2_1:8,P00552,1.11014,NO,40,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.645,-3.566,0.921,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.100394,0.00693477,1.11014 kka2_1:8_S40G,kka2_1:8_40,Kka2,kka2_1:8,P00552,1.11014,NO,40,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.645,-3.566,0.921,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.100394,0.00693477,1.11014 beta-lactamase_0_T138C,beta-lactamase_0_138,TEM-1,beta-lactamase_0,P62593,1.11015,NO,138,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.506,-5.125,2.619,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.0500837,0.00487868,1.11015 kka2_1:4_A166G,kka2_1:4_166,Kka2,kka2_1:4,P00552,1.11024,NO,166,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.407,-2.83,0.423,,0.534,.,B,0.46,1.03,,,71.59,HHO,-2.421,0.168804,0.00799912,1.11024 kka2_1:4_G95E,kka2_1:4_95,Kka2,kka2_1:4,P00552,1.11034,NO,95,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-2.403,-2.685,0.282,,0.126,E,B,0.29,-0.74,0.359,,71.59,HOA,-2.198,0.168804,0.00743616,1.11034 kka2_1:4_E160R,kka2_1:4_160,Kka2,kka2_1:4,P00552,1.11035,NO,160,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.683,-3.847,2.164,,0.989,G,A,1.04,2.28,2.531,,71.59,AAA,-1.36133,0.168804,0.00935762,1.11035 kka2_1:2_Q4V,kka2_1:2_4,Kka2,kka2_1:2,P00552,1.11046,NO,4,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.361,-3.536,1.175,,,,,,,2.026,,71.59,APA,-1.95533,0.295029,0.00239179,1.11046 beta-lactamase_0_K190T,beta-lactamase_0_190,TEM-1,beta-lactamase_0,P62593,1.11057,NO,190,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.994,-2.389,0.395,,0.371,H,A,2.34,0.16,16.606,16.606,77.62,BBH,-1.64167,0.0500837,0.00574527,1.11057 kka2_1:4_C209T,kka2_1:4_209,Kka2,kka2_1:4,P00552,1.11062,NO,209,C,T,CT,Special,Polar,5.07,5.6,0.53,149,121,119,-2,108.5,116.1,7.6,-0.906,-3.473,2.567,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.168804,0.00260862,1.11062 kka2_1:8_N200E,kka2_1:8_200,Kka2,kka2_1:8,P00552,1.11062,NO,200,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-2.446,-2.236,-0.21,,0.756,T,L,0.43,-0.08,2.528,,64.39,APO,-2.08,0.100394,0.00838549,1.11062 kka2_1:8_N200E,kka2_1:8_200,Kka2,kka2_1:8,P00552,1.11062,NO,200,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-2.446,-2.236,-0.21,,0.756,T,L,0.43,-0.08,2.528,,64.39,APO,-2.08,0.100394,0.00838549,1.11062 beta-lactamase_0_A77L,beta-lactamase_0_77,TEM-1,beta-lactamase_0,P62593,1.11067,NO,77,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.234,-2.423,1.189,,0.039,H,A,0.46,-0.56,2.591,,64.34,OHH,-1.294,0.0500837,0.00282362,1.11067 beta-lactamase_0_I285A,beta-lactamase_0_285,TEM-1,beta-lactamase_0,P62593,1.11067,NO,285,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.0500837,0.101555,1.11067 kka2_1:4_E3G,kka2_1:4_3,Kka2,kka2_1:4,P00552,1.11069,NO,3,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.199,-2.062,-0.137,,,,,,,7.22,,92.05,HAP,-2.11567,0.168804,0.00267607,1.11069 kka2_1:8_E230Q,kka2_1:8_230,Kka2,kka2_1:8,P00552,1.11072,NO,230,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.672,-4.02,1.348,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.100394,0.00920051,1.11072 kka2_1:8_E230Q,kka2_1:8_230,Kka2,kka2_1:8,P00552,1.11072,NO,230,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.672,-4.02,1.348,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.100394,0.00920051,1.11072 beta-lactamase_0_N152W,beta-lactamase_0_152,TEM-1,beta-lactamase_0,P62593,1.11075,NO,152,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-2.757,-5.472,2.715,,0.863,H,A,0.61,0.92,2.151,,77.62,BPH,-2.97,0.0500837,0.00471429,1.11075 kka2_1:8_E199A,kka2_1:8_199,Kka2,kka2_1:8,P00552,1.11081,NO,199,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.234,-2.101,-0.133,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.100394,0.00854122,1.11081 kka2_1:8_E199A,kka2_1:8_199,Kka2,kka2_1:8,P00552,1.11081,NO,199,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.234,-2.101,-0.133,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.100394,0.00854122,1.11081 beta-lactamase_0_G281C,beta-lactamase_0_281,TEM-1,beta-lactamase_0,P62593,1.11084,NO,281,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.0500837,0.0406482,1.11084 kka2_1:8_G95T,kka2_1:8_95,Kka2,kka2_1:8,P00552,1.11084,NO,95,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-2.403,-1.849,-0.554,,0.126,E,B,0.75,-0.74,7.774,,71.59,HOA,-2.198,0.100394,0.00743616,1.11084 kka2_1:8_G95T,kka2_1:8_95,Kka2,kka2_1:8,P00552,1.11084,NO,95,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-2.403,-1.849,-0.554,,0.126,E,B,0.75,-0.74,7.774,,71.59,HOA,-2.198,0.100394,0.00743616,1.11084 WW_domain_S183A,WW_domain_183,Yap65,WW_domain,P46937,1.11086,NO,183,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.95,-2.029,0.079,5.35576,,,,,,1.594,,83.93,PPP,-1.48733,0.153962,0.00445513,1.11086 kka2_1:2_D5M,kka2_1:2_5,Kka2,kka2_1:2,P00552,1.11091,NO,5,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.306,-4.66,3.354,,,,,,,,,71.59,PAO,-1.784,0.295029,0.00222864,1.11091 beta-lactamase_0_E102M,beta-lactamase_0_102,TEM-1,beta-lactamase_0,P62593,1.11092,NO,102,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.118,-4.799,2.681,,0.722,S,B,1.04,1.82,4.773,,73.08,HAH,-1.581,0.0500837,0.00486633,1.11092 beta-lactamase_0_T264S,beta-lactamase_0_264,TEM-1,beta-lactamase_0,P62593,1.11095,NO,264,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.985,-1.764,-0.221,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.0500837,0.0119399,1.11095 beta-lactamase_0_S57K,beta-lactamase_0_57,TEM-1,beta-lactamase_0,P62593,1.11096,NO,57,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.918,-3.565,1.647,,0.352,E,B,0.27,-0.18,1.454,,72.73,APH,-2.29167,0.0500837,0.00492804,1.11096 kka2_1:4_S68G,kka2_1:4_68,Kka2,kka2_1:4,P00552,1.111,NO,68,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.623,-2.541,-0.082,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.168804,0.00608265,1.111 kka2_1:4_S54G,kka2_1:4_54,Kka2,kka2_1:4,P00552,1.11101,NO,54,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.471,-2.892,0.421,,0.408,S,b,0.27,1.01,17.332,17.332,71.59,HPO,-2.259,0.168804,0.00782867,1.11101 kka2_1:1_D180F,kka2_1:1_180,Kka2,kka2_1:1,P00552,1.11104,NO,180,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.416,-4.402,1.986,,1.03,S,a,0.75,1.5,1.534,,71.59,OAO,-2.02933,0.520039,0.00756412,1.11104 kka2_1:4_I2S,kka2_1:4_2,Kka2,kka2_1:4,P00552,1.11107,NO,2,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.787,-3.207,1.42,,,,,,,,,71.59,HHA,-1.92433,0.168804,0.00246644,1.11107 kka2_1:4_T187S,kka2_1:4_187,Kka2,kka2_1:4,P00552,1.11109,NO,187,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.273,-2.293,1.02,,0.007,E,B,0.22,-0.85,2.73,,52.27,HPB,-1.06567,0.168804,0.00693073,1.11109 kka2_1:2_E96Q,kka2_1:2_96,Kka2,kka2_1:2,P00552,1.11115,NO,96,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.573,-3.937,1.364,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.295029,0.00369441,1.11115 beta-lactamase_0_V29A,beta-lactamase_0_29,TEM-1,beta-lactamase_0,P62593,1.11116,NO,29,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-2.856,-2.61,-0.246,,0.733,H,A,0.44,-0.78,21.916,21.916,93.01,HHB,-2.24733,0.0500837,0.00318969,1.11116 kka2_1:8_A78G,kka2_1:8_78,Kka2,kka2_1:8,P00552,1.11121,NO,78,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.744,-3.281,1.537,,0.078,,B,1.04,-0.53,1.251,,56.06,OHH,-1.863,0.100394,0.00457299,1.11121 kka2_1:8_A78G,kka2_1:8_78,Kka2,kka2_1:8,P00552,1.11121,NO,78,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.744,-3.281,1.537,,0.078,,B,1.04,-0.53,1.251,,56.06,OHH,-1.863,0.100394,0.00457299,1.11121 beta-lactamase_0_I45Y,beta-lactamase_0_45,TEM-1,beta-lactamase_0,P62593,1.11123,NO,45,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-2.421,-2.914,0.493,,,E,B,0.48,-0.3,1.375,,77.62,HHA,-2.30267,0.0500837,0.00452842,1.11123 beta-lactamase_0_R118P,beta-lactamase_0_118,TEM-1,beta-lactamase_0,P62593,1.11123,NO,118,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.413,-3.946,1.533,,0.457,H,A,1.2,1.39,3.961,,77.62,HBA,-1.785,0.0500837,0.00538794,1.11123 kka2_1:8_P98C,kka2_1:8_98,Kka2,kka2_1:8,P00552,1.11123,NO,98,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.526,-5.171,3.645,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.100394,0.00622754,1.11123 kka2_1:8_P98C,kka2_1:8_98,Kka2,kka2_1:8,P00552,1.11123,NO,98,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.526,-5.171,3.645,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.100394,0.00622754,1.11123 kka2_1:8_H139C,kka2_1:8_139,Kka2,kka2_1:8,P00552,1.11124,NO,139,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-2.809,-5.201,2.392,,0.471,H,A,0.17,0.68,28.583,28.583,63.64,BBB,-2.22,0.100394,0.00734779,1.11124 kka2_1:8_H139C,kka2_1:8_139,Kka2,kka2_1:8,P00552,1.11124,NO,139,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-2.809,-5.201,2.392,,0.471,H,A,0.17,0.68,28.583,28.583,63.64,BBB,-2.22,0.100394,0.00734779,1.11124 PSD95pdz3_G335H,PSD95pdz3_335,PSD95pdz3,PSD95pdz3,P31016,1.11126,NO,335,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.008,-4.362,3.354,4.76223,,,,,22.4225,,,,AOH,-1.34733,0.0758425,0.000900493,1.11126 kka2_1:8_E199K,kka2_1:8_199,Kka2,kka2_1:8,P00552,1.11127,NO,199,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.234,-3.055,0.821,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.100394,0.00854122,1.11127 kka2_1:8_E199K,kka2_1:8_199,Kka2,kka2_1:8,P00552,1.11127,NO,199,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.234,-3.055,0.821,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.100394,0.00854122,1.11127 kka2_1:8_G95M,kka2_1:8_95,Kka2,kka2_1:8,P00552,1.11127,NO,95,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-2.403,-4.756,2.353,,0.126,E,B,0.75,-0.74,7.774,,71.59,HOA,-2.198,0.100394,0.00743616,1.11127 kka2_1:8_G95M,kka2_1:8_95,Kka2,kka2_1:8,P00552,1.11127,NO,95,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-2.403,-4.756,2.353,,0.126,E,B,0.75,-0.74,7.774,,71.59,HOA,-2.198,0.100394,0.00743616,1.11127 beta-lactamase_0_M153F,beta-lactamase_0_153,TEM-1,beta-lactamase_0,P62593,1.11134,NO,153,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-3.193,-3.944,0.751,,0.14,T,A,0.55,-0.11,3.826,,77.62,PHO,-2.25767,0.0500837,0.00509109,1.11134 kka2_1:8_A166Y,kka2_1:8_166,Kka2,kka2_1:8,P00552,1.11134,NO,166,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.407,-4.444,2.037,,0.534,,B,1.04,1.03,13.995,13.995,71.59,HHO,-2.421,0.100394,0.00799912,1.11134 kka2_1:8_A166Y,kka2_1:8_166,Kka2,kka2_1:8,P00552,1.11134,NO,166,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.407,-4.444,2.037,,0.534,,B,1.04,1.03,13.995,13.995,71.59,HHO,-2.421,0.100394,0.00799912,1.11134 kka2_1:8_A137K,kka2_1:8_137,Kka2,kka2_1:8,P00552,1.11135,NO,137,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.156,-3.751,1.595,,0.029,H,A,1.04,0.34,2.886,,63.26,PHB,-2.559,0.100394,0.00515054,1.11135 kka2_1:8_A137K,kka2_1:8_137,Kka2,kka2_1:8,P00552,1.11135,NO,137,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.156,-3.751,1.595,,0.029,H,A,1.04,0.34,2.886,,63.26,PHB,-2.559,0.100394,0.00515054,1.11135 kka2_1:8_L158V,kka2_1:8_158,Kka2,kka2_1:8,P00552,1.11136,NO,158,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.947,-2.604,0.657,,0.095,.,B,0.55,0.77,1.607,,63.64,AHA,-1.25333,0.100394,0.00529068,1.11136 kka2_1:8_L158V,kka2_1:8_158,Kka2,kka2_1:8,P00552,1.11136,NO,158,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.947,-2.604,0.657,,0.095,.,B,0.55,0.77,1.607,,63.64,AHA,-1.25333,0.100394,0.00529068,1.11136 kka2_1:8_R173D,kka2_1:8_173,Kka2,kka2_1:8,P00552,1.11141,NO,173,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.407,-2.431,0.024,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.100394,0.00784999,1.11141 kka2_1:8_R173D,kka2_1:8_173,Kka2,kka2_1:8,P00552,1.11141,NO,173,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.407,-2.431,0.024,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.100394,0.00784999,1.11141 PSD95pdz3_G335A,PSD95pdz3_335,PSD95pdz3,PSD95pdz3,P31016,1.11143,NO,335,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.008,-2.534,1.526,4.76223,,,,,22.4225,,,,AOH,-1.34733,0.0758425,0.000900493,1.11143 kka2_1:8_D23S,kka2_1:8_23,Kka2,kka2_1:8,P00552,1.11144,NO,23,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.459,-2.448,-0.011,,0.695,E,B,0.75,-0.65,,,65.53,HAH,-1.94033,0.100394,0.007195,1.11144 kka2_1:8_D23S,kka2_1:8_23,Kka2,kka2_1:8,P00552,1.11144,NO,23,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.459,-2.448,-0.011,,0.695,E,B,0.75,-0.65,,,65.53,HAH,-1.94033,0.100394,0.007195,1.11144 kka2_1:8_P45K,kka2_1:8_45,Kka2,kka2_1:8,P00552,1.11148,NO,45,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.774,-2.635,0.861,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.100394,0.00590481,1.11148 kka2_1:8_P45K,kka2_1:8_45,Kka2,kka2_1:8,P00552,1.11148,NO,45,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.774,-2.635,0.861,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.100394,0.00590481,1.11148 beta-lactamase_0_A247L,beta-lactamase_0_247,TEM-1,beta-lactamase_0,P62593,1.11151,NO,247,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.48,-2.56,1.08,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.0500837,0.00611275,1.11151 kka2_1:8_T72Y,kka2_1:8_72,Kka2,kka2_1:8,P00552,1.11152,NO,72,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.38,-4.457,2.077,,0.784,H,A,0.22,0.29,3.603,,65.53,HPP,-2.238,0.100394,0.00750756,1.11152 kka2_1:8_T72Y,kka2_1:8_72,Kka2,kka2_1:8,P00552,1.11152,NO,72,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.38,-4.457,2.077,,0.784,H,A,0.22,0.29,3.603,,65.53,HPP,-2.238,0.100394,0.00750756,1.11152 kka2_1:4_G151S,kka2_1:4_151,Kka2,kka2_1:4,P00552,1.11156,NO,151,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.873,-2.614,1.741,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.168804,0.00339918,1.11156 beta-lactamase_0_I277S,beta-lactamase_0_277,TEM-1,beta-lactamase_0,P62593,1.1116,NO,277,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.0500837,0.0169305,1.1116 kka2_1:4_P128I,kka2_1:4_128,Kka2,kka2_1:4,P00552,1.11164,NO,128,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.922,-1.808,-0.114,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.168804,0.00774689,1.11164 kka2_1:8_Q155F,kka2_1:8_155,Kka2,kka2_1:8,P00552,1.11171,NO,155,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.606,-4.366,1.76,,0.525,T,A,0.64,1.49,,,63.64,APA,-1.726,0.100394,0.00641853,1.11171 kka2_1:8_Q155F,kka2_1:8_155,Kka2,kka2_1:8,P00552,1.11171,NO,155,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.606,-4.366,1.76,,0.525,T,A,0.64,1.49,,,63.64,APA,-1.726,0.100394,0.00641853,1.11171 kka2_1:4_G164T,kka2_1:4_164,Kka2,kka2_1:4,P00552,1.11172,NO,164,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.869,-3.578,2.709,,0.862,T,l,0.75,1.45,1.539,,64.39,POH,-1.828,0.168804,0.00442091,1.11172 kka2_1:4_E169L,kka2_1:4_169,Kka2,kka2_1:4,P00552,1.11181,NO,169,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.996,-3.06,1.064,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.168804,0.00730086,1.11181 beta-lactamase_0_I45L,beta-lactamase_0_45,TEM-1,beta-lactamase_0,P62593,1.11182,NO,45,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-2.421,-2.39,-0.031,,,E,B,0.48,-0.3,1.375,,77.62,HHA,-2.30267,0.0500837,0.00452842,1.11182 PSD95pdz3_G335R,PSD95pdz3_335,PSD95pdz3,PSD95pdz3,P31016,1.11186,NO,335,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.008,-3.615,2.607,4.76223,,,,,22.4225,,,,AOH,-1.34733,0.0758425,0.000900493,1.11186 beta-lactamase_0_D177E,beta-lactamase_0_177,TEM-1,beta-lactamase_0,P62593,1.11187,NO,177,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.967,-2.98,2.013,,0.006,T,L,0.75,-1.02,3.536,,64.69,BAP,-0.873667,0.0500837,0.000864022,1.11187 kka2_1:4_R18G,kka2_1:4_18,Kka2,kka2_1:4,P00552,1.11187,NO,18,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.055,-3.057,1.002,,0.474,T,A,1.2,0.54,8.405,8.405,71.59,ABH,-1.821,0.168804,0.00724065,1.11187 kka2_1:2_Q42L,kka2_1:2_42,Kka2,kka2_1:2,P00552,1.11188,NO,42,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.907,-2.953,0.046,,1.044,T,B,0.64,-0.8,2.792,,71.59,HPO,-2.12433,0.295029,0.00679212,1.11188 kka2_1:8_G21Q,kka2_1:8_21,Kka2,kka2_1:8,P00552,1.11194,NO,21,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.368,-2.867,1.499,,0.586,T,l,0.29,-0.75,4.889,,71.59,HOH,-2.10167,0.100394,0.00709648,1.11194 kka2_1:8_G21Q,kka2_1:8_21,Kka2,kka2_1:8,P00552,1.11194,NO,21,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.368,-2.867,1.499,,0.586,T,l,0.29,-0.75,4.889,,71.59,HOH,-2.10167,0.100394,0.00709648,1.11194 beta-lactamase_0_Q276Y,beta-lactamase_0_276,TEM-1,beta-lactamase_0,P62593,1.11195,NO,276,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-1.144,,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.0500837,0.0191712,1.11195 WW_domain_S183R,WW_domain_183,Yap65,WW_domain,P46937,1.11197,NO,183,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-1.95,-3.688,1.738,5.35576,,,,,,1.594,,83.93,PPP,-1.48733,0.153962,0.00445513,1.11197 kka2_1:4_L165N,kka2_1:4_165,Kka2,kka2_1:4,P00552,1.11198,NO,165,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-2.453,-3.932,1.479,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.168804,0.00801161,1.11198 PSD95pdz3_Q391W,PSD95pdz3_391,PSD95pdz3,PSD95pdz3,P31016,1.11198,NO,391,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-1.699,-4.779,3.08,5.50275,,,,,12.6589,,,,HPH,-1.481,0.0758425,0.000990786,1.11198 PSD95pdz3_I314N,PSD95pdz3_314,PSD95pdz3,PSD95pdz3,P31016,1.11201,NO,314,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.628,-3.9,2.272,5.39919,,,,,15.7775,0.397,,81.35,BHH,-1.61167,0.0758425,0.0012606,1.11201 kka2_1:1_A13R,kka2_1:1_13,Kka2,kka2_1:1,P00552,1.11205,NO,13,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.248,-2.994,0.746,,0.689,G,A,0.46,0.99,25.015,25.015,92.05,OHH,-1.646,0.520039,0.00784241,1.11205 kka2_1:8_C192I,kka2_1:8_192,Kka2,kka2_1:8,P00552,1.11205,NO,192,C,I,CI,Special,Hydrophobic,5.07,6.02,0.95,198,121,131,10,108.5,166.7,58.2,-1.067,-3.687,2.62,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.100394,0.00485428,1.11205 kka2_1:8_C192I,kka2_1:8_192,Kka2,kka2_1:8,P00552,1.11205,NO,192,C,I,CI,Special,Hydrophobic,5.07,6.02,0.95,198,121,131,10,108.5,166.7,58.2,-1.067,-3.687,2.62,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.100394,0.00485428,1.11205 kka2_1:8_G151E,kka2_1:8_151,Kka2,kka2_1:8,P00552,1.11207,NO,151,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.873,-3.557,2.684,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.100394,0.00339918,1.11207 kka2_1:8_G151E,kka2_1:8_151,Kka2,kka2_1:8,P00552,1.11207,NO,151,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.873,-3.557,2.684,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.100394,0.00339918,1.11207 kka2_1:8_Q136A,kka2_1:8_136,Kka2,kka2_1:8,P00552,1.11211,NO,136,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-3.021,-3.149,0.128,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.100394,0.00624149,1.11211 kka2_1:8_Q136A,kka2_1:8_136,Kka2,kka2_1:8,P00552,1.11211,NO,136,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-3.021,-3.149,0.128,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.100394,0.00624149,1.11211 kka2_1:2_E142Q,kka2_1:2_142,Kka2,kka2_1:2,P00552,1.1122,NO,142,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.221,-3.009,0.788,,0.471,H,A,1.52,0.85,3.693,,65.53,HAB,-2.08033,0.295029,0.00748883,1.1122 beta-lactamase_0_R159E,beta-lactamase_0_159,TEM-1,beta-lactamase_0,P62593,1.1123,NO,159,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-0.94,-3.241,2.301,,0.316,,B,1.2,-0.55,1.426,,64.34,PBH,-1.011,0.0500837,0.00108472,1.1123 kka2_1:8_L53K,kka2_1:8_53,Kka2,kka2_1:8,P00552,1.11237,NO,53,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-2.681,-3.091,0.41,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.100394,0.00671168,1.11237 kka2_1:8_L53K,kka2_1:8_53,Kka2,kka2_1:8,P00552,1.11237,NO,53,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-2.681,-3.091,0.41,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.100394,0.00671168,1.11237 kka2_1:8_D154G,kka2_1:8_154,Kka2,kka2_1:8,P00552,1.1124,NO,154,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.876,-3.201,2.325,,0.457,,b,0.29,1.48,0.844,,52.65,HAP,-1.52467,0.100394,0.00292633,1.1124 kka2_1:8_D154G,kka2_1:8_154,Kka2,kka2_1:8,P00552,1.1124,NO,154,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.876,-3.201,2.325,,0.457,,b,0.29,1.48,0.844,,52.65,HAP,-1.52467,0.100394,0.00292633,1.1124 kka2_1:8_K175H,kka2_1:8_175,Kka2,kka2_1:8,P00552,1.11242,NO,175,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-2.897,-3.28,0.383,,0.579,H,A,2.34,0.51,15.316,15.316,71.59,HBH,-1.82333,0.100394,0.00693093,1.11242 kka2_1:8_K175H,kka2_1:8_175,Kka2,kka2_1:8,P00552,1.11242,NO,175,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-2.897,-3.28,0.383,,0.579,H,A,2.34,0.51,15.316,15.316,71.59,HBH,-1.82333,0.100394,0.00693093,1.11242 kka2_1:4_A255S,kka2_1:4_255,Kka2,kka2_1:4,P00552,1.11246,NO,255,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.715,-2.589,0.874,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.168804,0.0126809,1.11246 WW_domain_I193K,WW_domain_193,Yap65,WW_domain,P46937,1.11258,NO,193,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.993,-3.547,1.554,6.15906,,,,,,1.833,,83.33,BHA,-1.756,0.153962,0.00587613,1.11258 kka2_1:8_Q155P,kka2_1:8_155,Kka2,kka2_1:8,P00552,1.11268,NO,155,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.606,-3.826,1.22,,0.525,T,A,0.64,1.49,,,63.64,APA,-1.726,0.100394,0.00641853,1.11268 kka2_1:8_Q155P,kka2_1:8_155,Kka2,kka2_1:8,P00552,1.11268,NO,155,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.606,-3.826,1.22,,0.525,T,A,0.64,1.49,,,63.64,APA,-1.726,0.100394,0.00641853,1.11268 kka2_1:1_A247D,kka2_1:1_247,Kka2,kka2_1:1,P00552,1.11269,NO,247,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.459,-3.029,0.57,,1.01,S,A,0.46,0.65,7.731,7.731,92.05,HHH,-2.197,0.520039,0.0102428,1.11269 kka2_1:2_P76N,kka2_1:2_76,Kka2,kka2_1:2,P00552,1.11282,NO,76,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.449,-3.923,2.474,,0.331,.,B,0.52,-0.41,0.345,,63.64,HOO,-1.662,0.295029,0.00625685,1.11282 kka2_1:8_G164T,kka2_1:8_164,Kka2,kka2_1:8,P00552,1.11283,NO,164,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.869,-3.578,2.709,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.100394,0.00442091,1.11283 kka2_1:8_G164T,kka2_1:8_164,Kka2,kka2_1:8,P00552,1.11283,NO,164,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.869,-3.578,2.709,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.100394,0.00442091,1.11283 kka2_1:4_V83E,kka2_1:4_83,Kka2,kka2_1:4,P00552,1.11287,NO,83,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-2.567,-2.291,-0.276,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.168804,0.00650486,1.11287 kka2_1:4_L174C,kka2_1:4_174,Kka2,kka2_1:4,P00552,1.11289,NO,174,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.952,-4.719,3.767,,,H,A,0.55,-0.31,1.339,,51.89,BHB,-2.08533,0.168804,0.00438501,1.11289 beta-lactamase_0_R220G,beta-lactamase_0_220,TEM-1,beta-lactamase_0,P62593,1.11291,NO,220,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-0.942,-3.321,2.379,,0.295,I,A,1.2,-0.76,21.573,21.573,74.48,HBP,-1.33633,0.0500837,0.00232421,1.11291 beta-lactamase_0_T269A,beta-lactamase_0_269,TEM-1,beta-lactamase_0,P62593,1.11295,NO,269,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.0500837,0.00950944,1.11295 kka2_1:8_A13W,kka2_1:8_13,Kka2,kka2_1:8,P00552,1.11298,NO,13,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.248,-3.869,1.621,,0.689,G,A,1.04,0.99,14.966,14.966,92.05,OHH,-1.646,0.100394,0.00784241,1.11298 kka2_1:8_A13W,kka2_1:8_13,Kka2,kka2_1:8,P00552,1.11298,NO,13,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.248,-3.869,1.621,,0.689,G,A,1.04,0.99,14.966,14.966,92.05,OHH,-1.646,0.100394,0.00784241,1.11298 kka2_1:8_E199D,kka2_1:8_199,Kka2,kka2_1:8,P00552,1.11311,NO,199,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.234,-2.172,-0.062,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.100394,0.00854122,1.11311 kka2_1:8_E199D,kka2_1:8_199,Kka2,kka2_1:8,P00552,1.11311,NO,199,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.234,-2.172,-0.062,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.100394,0.00854122,1.11311 beta-lactamase_0_A225N,beta-lactamase_0_225,TEM-1,beta-lactamase_0,P62593,1.11329,NO,225,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.845,-3.051,1.206,,1,T,B,0.46,-0.38,11.722,11.722,74.48,OHO,-1.39967,0.0500837,0.00465057,1.11329 WW_domain_R187N,WW_domain_187,Yap65,WW_domain,P46937,1.11329,NO,187,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.402,-3.288,1.886,5.05189,,,,,,3.431,,78.57,PBH,-1.362,0.153962,0.00171149,1.11329 beta-lactamase_0_E145M,beta-lactamase_0_145,TEM-1,beta-lactamase_0,P62593,1.11332,NO,145,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.357,-4.807,2.45,,0.545,H,A,1.04,0.79,1.199,,77.62,BAH,-2.069,0.0500837,0.00553285,1.11332 kka2_1:8_D127H,kka2_1:8_127,Kka2,kka2_1:8,P00552,1.11333,NO,127,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.364,-4.683,3.319,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.100394,0.00660501,1.11333 kka2_1:8_D127H,kka2_1:8_127,Kka2,kka2_1:8,P00552,1.11333,NO,127,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.364,-4.683,3.319,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.100394,0.00660501,1.11333 kka2_1:8_Q219L,kka2_1:8_219,Kka2,kka2_1:8,P00552,1.11333,NO,219,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-0.93,-3.41,2.48,,0.088,H,A,0.4,-0.85,0.897,,50,HPA,-1.05167,0.100394,0.00237913,1.11333 kka2_1:8_Q219L,kka2_1:8_219,Kka2,kka2_1:8,P00552,1.11333,NO,219,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-0.93,-3.41,2.48,,0.088,H,A,0.4,-0.85,0.897,,50,HPA,-1.05167,0.100394,0.00237913,1.11333 beta-lactamase_0_L120G,beta-lactamase_0_120,TEM-1,beta-lactamase_0,P62593,1.11335,NO,120,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.044,-3.788,2.744,,,H,A,0.55,-1.13,1.2,,64.69,AHO,-1.13633,0.0500837,0.00143563,1.11335 kka2_1:8_E169D,kka2_1:8_169,Kka2,kka2_1:8,P00552,1.1134,NO,169,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.996,-1.998,0.002,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.100394,0.00730086,1.1134 kka2_1:8_E169D,kka2_1:8_169,Kka2,kka2_1:8,P00552,1.1134,NO,169,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.996,-1.998,0.002,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.100394,0.00730086,1.1134 beta-lactamase_0_T178K,beta-lactamase_0_178,TEM-1,beta-lactamase_0,P62593,1.11347,NO,178,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-0.791,-3.457,2.666,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.0500837,0.000684366,1.11347 kka2_1:8_D33F,kka2_1:8_33,Kka2,kka2_1:8,P00552,1.11347,NO,33,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.186,-4.506,2.32,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.100394,0.00633568,1.11347 kka2_1:8_D33F,kka2_1:8_33,Kka2,kka2_1:8,P00552,1.11347,NO,33,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.186,-4.506,2.32,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.100394,0.00633568,1.11347 kka2_1:8_E142C,kka2_1:8_142,Kka2,kka2_1:8,P00552,1.1135,NO,142,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.221,-5.114,2.893,,0.471,H,A,1.04,0.85,2.655,,65.53,HAB,-2.08033,0.100394,0.00748883,1.1135 kka2_1:8_E142C,kka2_1:8_142,Kka2,kka2_1:8,P00552,1.1135,NO,142,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.221,-5.114,2.893,,0.471,H,A,1.04,0.85,2.655,,65.53,HAB,-2.08033,0.100394,0.00748883,1.1135 beta-lactamase_0_Q88A,beta-lactamase_0_88,TEM-1,beta-lactamase_0,P62593,1.1136,NO,88,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.086,-2.75,0.664,,0.807,,B,0.64,2.03,0.4,,77.62,APH,-1.53433,0.0500837,0.00504167,1.1136 kka2_1:4_D156W,kka2_1:4_156,Kka2,kka2_1:4,P00552,1.11364,NO,156,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.696,-5.547,3.851,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.168804,0.00926998,1.11364 beta-lactamase_0_Q37Y,beta-lactamase_0_37,TEM-1,beta-lactamase_0,P62593,1.11366,NO,37,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.134,-4.193,2.059,,0.613,H,A,0.64,1.98,4.001,,73.08,APH,-2.06967,0.0500837,0.00425833,1.11366 kka2_1:8_A110Y,kka2_1:8_110,Kka2,kka2_1:8,P00552,1.11366,NO,110,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.064,-4.356,2.292,,0.175,H,A,1.04,-1.19,11.413,11.413,71.59,OHA,-1.91867,0.100394,0.00759851,1.11366 kka2_1:8_A110Y,kka2_1:8_110,Kka2,kka2_1:8,P00552,1.11366,NO,110,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.064,-4.356,2.292,,0.175,H,A,1.04,-1.19,11.413,11.413,71.59,OHA,-1.91867,0.100394,0.00759851,1.11366 beta-lactamase_0_V31D,beta-lactamase_0_31,TEM-1,beta-lactamase_0,P62593,1.11369,NO,31,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.822,-4.049,2.227,,,H,A,0.44,-0.46,4.126,,73.78,BHB,-2.03767,0.0500837,0.00478065,1.11369 beta-lactamase_0_P105W,beta-lactamase_0_105,TEM-1,beta-lactamase_0,P62593,1.1138,NO,105,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.813,-5.545,4.732,,0.226,T,A,0.52,0.8,3.48,,63.29,POH,-1.01533,0.0500837,0.0011981,1.1138 beta-lactamase_0_H94G,beta-lactamase_0_94,TEM-1,beta-lactamase_0,P62593,1.11382,NO,94,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-2.5,-3.593,1.093,,0.776,,B,0.17,1.24,1.176,,77.62,HBH,-1.872,0.0500837,0.00389226,1.11382 PSD95pdz3_E334I,PSD95pdz3_334,PSD95pdz3,PSD95pdz3,P31016,1.11384,NO,334,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.404,-3.692,2.288,5.60175,,,,,53.09,,,,OAO,-1.14,0.0758425,0.000912998,1.11384 beta-lactamase_0_I280D,beta-lactamase_0_280,TEM-1,beta-lactamase_0,P62593,1.11391,NO,280,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.0500837,0.0530888,1.11391 kka2_1:8_E160T,kka2_1:8_160,Kka2,kka2_1:8,P00552,1.11391,NO,160,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.683,-3.562,1.879,,0.989,G,A,1.04,2.28,2.164,,71.59,AAA,-1.36133,0.100394,0.00935762,1.11391 kka2_1:8_E160T,kka2_1:8_160,Kka2,kka2_1:8,P00552,1.11391,NO,160,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.683,-3.562,1.879,,0.989,G,A,1.04,2.28,2.164,,71.59,AAA,-1.36133,0.100394,0.00935762,1.11391 kka2_1:4_K175D,kka2_1:4_175,Kka2,kka2_1:4,P00552,1.11397,NO,175,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-2.897,-3.874,0.977,,0.579,H,A,1.3,0.51,15.629,15.629,71.59,HBH,-1.82333,0.168804,0.00693093,1.11397 beta-lactamase_0_V214E,beta-lactamase_0_214,TEM-1,beta-lactamase_0,P62593,1.11404,NO,214,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.299,-3.704,2.405,,0.375,S,A,0.44,-0.44,3.712,,74.48,BHH,-1.53733,0.0500837,0.00628442,1.11404 kka2_1:4_A9D,kka2_1:4_9,Kka2,kka2_1:4,P00552,1.11423,NO,9,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.079,-3.62,1.541,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.168804,0.00273264,1.11423 beta-lactamase_0_L38C,beta-lactamase_0_38,TEM-1,beta-lactamase_0,P62593,1.11429,NO,38,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.343,-4.841,3.498,,0.088,H,A,0.55,0.2,13.556,13.556,64.34,PHO,-1.78033,0.0500837,0.00373244,1.11429 kka2_1:2_A9F,kka2_1:2_9,Kka2,kka2_1:2,P00552,1.11431,NO,9,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.079,-3.934,1.855,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.295029,0.00273264,1.11431 beta-lactamase_0_T179R,beta-lactamase_0_179,TEM-1,beta-lactamase_0,P62593,1.11434,NO,179,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.085,-3.749,2.664,,,E,B,0.22,-1.38,0.367,,73.08,PPH,-1.557,0.0500837,0.00226045,1.11434 kka2_1:4_D157N,kka2_1:4_157,Kka2,kka2_1:4,P00552,1.11434,NO,157,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.993,-2.434,1.441,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.168804,0.0042313,1.11434 kka2_1:4_I207V,kka2_1:4_207,Kka2,kka2_1:4,P00552,1.11439,NO,207,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.175,-1.613,0.438,,0.293,.,B,0.48,-1.12,1.215,,56.06,HHA,-1.07733,0.168804,0.00611824,1.11439 kka2_1:8_L165C,kka2_1:8_165,Kka2,kka2_1:8,P00552,1.11441,NO,165,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-2.453,-5.171,2.718,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.100394,0.00801161,1.11441 kka2_1:8_L165C,kka2_1:8_165,Kka2,kka2_1:8,P00552,1.11441,NO,165,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-2.453,-5.171,2.718,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.100394,0.00801161,1.11441 beta-lactamase_0_E61V,beta-lactamase_0_61,TEM-1,beta-lactamase_0,P62593,1.11445,NO,61,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.115,-3.784,1.669,,0.775,T,a,1.04,1.29,34.763,34.763,77.62,OAA,-1.92567,0.0500837,0.00440955,1.11445 kka2_1:8_G88S,kka2_1:8_88,Kka2,kka2_1:8,P00552,1.11448,NO,88,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.689,-2.938,1.249,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.100394,0.00685559,1.11448 kka2_1:8_G88S,kka2_1:8_88,Kka2,kka2_1:8,P00552,1.11448,NO,88,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.689,-2.938,1.249,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.100394,0.00685559,1.11448 kka2_1:4_E86Q,kka2_1:4_86,Kka2,kka2_1:4,P00552,1.11449,NO,86,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.86,-2.883,1.023,,0.369,.,B,1.04,1.92,4.451,,63.26,PAH,-1.98067,0.168804,0.00642858,1.11449 kka2_1:8_G201R,kka2_1:8_201,Kka2,kka2_1:8,P00552,1.11455,NO,201,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.56,-2.756,1.196,,0.149,T,l,0.75,-0.57,2.152,,52.65,POB,-1.92233,0.100394,0.00820117,1.11455 kka2_1:8_G201R,kka2_1:8_201,Kka2,kka2_1:8,P00552,1.11455,NO,201,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.56,-2.756,1.196,,0.149,T,l,0.75,-0.57,2.152,,52.65,POB,-1.92233,0.100394,0.00820117,1.11455 kka2_1:8_P76D,kka2_1:8_76,Kka2,kka2_1:8,P00552,1.11457,NO,76,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.449,-2.541,1.092,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.100394,0.00625685,1.11457 kka2_1:8_P76D,kka2_1:8_76,Kka2,kka2_1:8,P00552,1.11457,NO,76,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.449,-2.541,1.092,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.100394,0.00625685,1.11457 kka2_1:2_M116L,kka2_1:2_116,Kka2,kka2_1:2,P00552,1.11458,NO,116,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-2.482,-1.52,-0.962,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.295029,0.00745147,1.11458 beta-lactamase_0_D33S,beta-lactamase_0_33,TEM-1,beta-lactamase_0,P62593,1.11465,NO,33,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.321,-2.627,0.306,,0.366,H,A,0.75,0.33,12.514,12.514,77.62,BAH,-2.12133,0.0500837,0.00435556,1.11465 beta-lactamase_0_M115C,beta-lactamase_0_115,TEM-1,beta-lactamase_0,P62593,1.11485,NO,115,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.389,-4.767,3.378,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.0500837,0.0034337,1.11485 kka2_1:4_A13S,kka2_1:4_13,Kka2,kka2_1:4,P00552,1.11486,NO,13,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.248,-2.545,0.297,,0.689,G,A,0.46,0.99,,,92.05,OHH,-1.646,0.168804,0.00784241,1.11486 kka2_1:8_S204T,kka2_1:8_204,Kka2,kka2_1:8,P00552,1.11488,NO,204,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.353,-1.747,0.394,,0.144,E,A,0.27,-1.2,0.368,,65.53,HPO,-0.953333,0.100394,0.00881794,1.11488 kka2_1:8_S204T,kka2_1:8_204,Kka2,kka2_1:8,P00552,1.11488,NO,204,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.353,-1.747,0.394,,0.144,E,A,0.27,-1.2,0.368,,65.53,HPO,-0.953333,0.100394,0.00881794,1.11488 kka2_1:8_D134F,kka2_1:8_134,Kka2,kka2_1:8,P00552,1.11489,NO,134,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.969,-4.314,3.345,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.100394,0.00270812,1.11489 kka2_1:8_D134F,kka2_1:8_134,Kka2,kka2_1:8,P00552,1.11489,NO,134,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.969,-4.314,3.345,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.100394,0.00270812,1.11489 beta-lactamase_0_S241V,beta-lactamase_0_241,TEM-1,beta-lactamase_0,P62593,1.11494,NO,241,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.0500837,0.00452736,1.11494 beta-lactamase_0_R220I,beta-lactamase_0_220,TEM-1,beta-lactamase_0,P62593,1.11504,NO,220,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-0.942,-3.974,3.032,,0.295,I,A,1.2,-0.76,21.573,21.573,74.48,HBP,-1.33633,0.0500837,0.00232421,1.11504 kka2_1:8_Q163A,kka2_1:8_163,Kka2,kka2_1:8,P00552,1.11504,NO,163,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.162,-2.603,0.441,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.100394,0.00719507,1.11504 kka2_1:8_Q163A,kka2_1:8_163,Kka2,kka2_1:8,P00552,1.11504,NO,163,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.162,-2.603,0.441,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.100394,0.00719507,1.11504 kka2_1:8_E235A,kka2_1:8_235,Kka2,kka2_1:8,P00552,1.11505,NO,235,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.955,-1.909,-0.046,,0.631,H,A,1.52,0.12,,,65.53,OAH,-2.07267,0.100394,0.0102806,1.11505 kka2_1:8_E235A,kka2_1:8_235,Kka2,kka2_1:8,P00552,1.11505,NO,235,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.955,-1.909,-0.046,,0.631,H,A,1.52,0.12,,,65.53,OAH,-2.07267,0.100394,0.0102806,1.11505 kka2_1:8_E169V,kka2_1:8_169,Kka2,kka2_1:8,P00552,1.11507,NO,169,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.996,-3.701,1.705,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.100394,0.00730086,1.11507 kka2_1:8_E169V,kka2_1:8_169,Kka2,kka2_1:8,P00552,1.11507,NO,169,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.996,-3.701,1.705,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.100394,0.00730086,1.11507 beta-lactamase_0_A148T,beta-lactamase_0_148,TEM-1,beta-lactamase_0,P62593,1.11513,NO,148,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.757,-2.508,0.751,,0.379,H,A,0.46,-0.55,19.42,19.42,72.73,PHH,-1.40167,0.0500837,0.00547053,1.11513 kka2_1:8_P98E,kka2_1:8_98,Kka2,kka2_1:8,P00552,1.11515,NO,98,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.526,-2.413,0.887,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.100394,0.00622754,1.11515 kka2_1:8_P98E,kka2_1:8_98,Kka2,kka2_1:8,P00552,1.11515,NO,98,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.526,-2.413,0.887,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.100394,0.00622754,1.11515 kka2_1:2_S114W,kka2_1:2_114,Kka2,kka2_1:2,P00552,1.11528,NO,114,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.527,-5.559,3.032,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.295029,0.00705262,1.11528 beta-lactamase_0_P181D,beta-lactamase_0_181,TEM-1,beta-lactamase_0,P62593,1.11531,NO,181,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.813,-3.518,2.705,,,H,A,0.52,-1.14,1.357,,61.54,HOH,-1.795,0.0500837,0.000703122,1.11531 kka2_1:8_D156W,kka2_1:8_156,Kka2,kka2_1:8,P00552,1.11531,NO,156,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.696,-5.547,3.851,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.100394,0.00926998,1.11531 kka2_1:8_D156W,kka2_1:8_156,Kka2,kka2_1:8,P00552,1.11531,NO,156,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.696,-5.547,3.851,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.100394,0.00926998,1.11531 kka2_1:8_S204N,kka2_1:8_204,Kka2,kka2_1:8,P00552,1.11534,NO,204,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.353,-3.559,2.206,,0.144,E,A,0.27,-1.2,0.368,,65.53,HPO,-0.953333,0.100394,0.00881794,1.11534 kka2_1:8_S204N,kka2_1:8_204,Kka2,kka2_1:8,P00552,1.11534,NO,204,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.353,-3.559,2.206,,0.144,E,A,0.27,-1.2,0.368,,65.53,HPO,-0.953333,0.100394,0.00881794,1.11534 kka2_1:8_R44C,kka2_1:8_44,Kka2,kka2_1:8,P00552,1.11537,NO,44,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.062,-5.189,3.127,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.100394,0.00745043,1.11537 kka2_1:8_R44C,kka2_1:8_44,Kka2,kka2_1:8,P00552,1.11537,NO,44,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.062,-5.189,3.127,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.100394,0.00745043,1.11537 beta-lactamase_0_A132F,beta-lactamase_0_132,TEM-1,beta-lactamase_0,P62593,1.11539,NO,132,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.9,-4.091,3.191,,,H,A,0.46,-0.93,2.249,,64.69,PHH,-1.138,0.0500837,0.000962524,1.11539 kka2_1:8_I29Q,kka2_1:8_29,Kka2,kka2_1:8,P00552,1.11545,NO,29,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.692,-2.968,1.276,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.100394,0.00619521,1.11545 kka2_1:8_I29Q,kka2_1:8_29,Kka2,kka2_1:8,P00552,1.11545,NO,29,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.692,-2.968,1.276,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.100394,0.00619521,1.11545 beta-lactamase_0_Q267S,beta-lactamase_0_267,TEM-1,beta-lactamase_0,P62593,1.1155,NO,267,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.0500837,0.0102128,1.1155 kka2_1:2_A41S,kka2_1:2_41,Kka2,kka2_1:2,P00552,1.11555,NO,41,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.879,-2.842,0.963,,0.184,.,B,0.46,-0.96,24.451,24.451,64.39,PHP,-2.477,0.295029,0.00543332,1.11555 gb1_T251M,gb1_251,gb1,gb1,P06654,1.11559,NO,251,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.794,-4.281,2.487,,,,,,,3.514,3.514,37.28,HPH,-1.56067,0.177985,0.00232932,1.11559 WW_domain_D170I,WW_domain_170,Yap65,WW_domain,P46937,1.11567,NO,170,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.213,-3.85,2.637,,,,,,,0.399,,15.87,OAH,-1.38,0.153962,0.00123319,1.11567 kka2_1:8_D118E,kka2_1:8_118,Kka2,kka2_1:8,P00552,1.1157,NO,118,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.07,-2.401,0.331,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.100394,0.0067852,1.1157 kka2_1:8_D118E,kka2_1:8_118,Kka2,kka2_1:8,P00552,1.1157,NO,118,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.07,-2.401,0.331,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.100394,0.0067852,1.1157 beta-lactamase_0_A222L,beta-lactamase_0_222,TEM-1,beta-lactamase_0,P62593,1.11572,NO,222,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.103,-3.403,1.3,,0.233,H,A,0.46,-0.25,2.015,,77.62,PHH,-1.63733,0.0500837,0.00466094,1.11572 beta-lactamase_0_L136K,beta-lactamase_0_136,TEM-1,beta-lactamase_0,P62593,1.11574,NO,136,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.232,-3.824,2.592,,,H,A,0.55,-0.34,0.648,,48.95,HHH,-1.088,0.0500837,0.00442304,1.11574 kka2_1:4_P98C,kka2_1:4_98,Kka2,kka2_1:4,P00552,1.11575,NO,98,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.526,-5.171,3.645,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.168804,0.00622754,1.11575 kka2_1:2_D5K,kka2_1:2_5,Kka2,kka2_1:2,P00552,1.11578,NO,5,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.306,-3.094,1.788,,,,,,,,,71.59,PAO,-1.784,0.295029,0.00222864,1.11578 kka2_1:8_E142R,kka2_1:8_142,Kka2,kka2_1:8,P00552,1.1158,NO,142,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.221,-2.483,0.262,,0.471,H,A,1.04,0.85,2.655,,65.53,HAB,-2.08033,0.100394,0.00748883,1.1158 kka2_1:8_E142R,kka2_1:8_142,Kka2,kka2_1:8,P00552,1.1158,NO,142,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.221,-2.483,0.262,,0.471,H,A,1.04,0.85,2.655,,65.53,HAB,-2.08033,0.100394,0.00748883,1.1158 kka2_1:8_Q100L,kka2_1:8_100,Kka2,kka2_1:8,P00552,1.11581,NO,100,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.77,-2.853,0.083,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.100394,0.0066405,1.11581 kka2_1:8_Q100L,kka2_1:8_100,Kka2,kka2_1:8,P00552,1.11581,NO,100,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.77,-2.853,0.083,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.100394,0.0066405,1.11581 kka2_1:8_A64K,kka2_1:8_64,Kka2,kka2_1:8,P00552,1.11588,NO,64,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.496,-3.777,2.281,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.100394,0.00705578,1.11588 kka2_1:8_A64K,kka2_1:8_64,Kka2,kka2_1:8,P00552,1.11588,NO,64,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.496,-3.777,2.281,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.100394,0.00705578,1.11588 kka2_1:2_V83M,kka2_1:2_83,Kka2,kka2_1:2,P00552,1.11603,NO,83,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-2.567,-3.575,1.008,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.295029,0.00650486,1.11603 kka2_1:4_I29Q,kka2_1:4_29,Kka2,kka2_1:4,P00552,1.1161,NO,29,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.692,-2.968,1.276,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.168804,0.00619521,1.1161 beta-lactamase_0_Q88E,beta-lactamase_0_88,TEM-1,beta-lactamase_0,P62593,1.11613,NO,88,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.086,-2.76,0.674,,0.807,,B,0.64,2.03,0.4,,77.62,APH,-1.53433,0.0500837,0.00504167,1.11613 kka2_1:2_G55N,kka2_1:2_55,Kka2,kka2_1:2,P00552,1.11617,NO,55,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.625,-3.05,1.425,,0.517,S,b,0.75,1.19,15.753,15.753,63.64,POH,-2.05967,0.295029,0.00667877,1.11617 PSD95pdz3_I338S,PSD95pdz3_338,PSD95pdz3,PSD95pdz3,P31016,1.11618,NO,338,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.63,-3.292,1.662,5.45113,,,,,13.0087,,,,HHP,-1.55767,0.0758425,0.000862587,1.11618 kka2_1:4_A56F,kka2_1:4_56,Kka2,kka2_1:4,P00552,1.11623,NO,56,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.083,-4.441,2.358,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.168804,0.00717715,1.11623 kka2_1:8_A79E,kka2_1:8_79,Kka2,kka2_1:8,P00552,1.11628,NO,79,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.368,-2.303,-0.065,,0.563,.,B,0.46,-0.43,,,71.59,HHH,-1.752,0.100394,0.00664821,1.11628 kka2_1:8_A79E,kka2_1:8_79,Kka2,kka2_1:8,P00552,1.11628,NO,79,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.368,-2.303,-0.065,,0.563,.,B,0.46,-0.43,,,71.59,HHH,-1.752,0.100394,0.00664821,1.11628 kka2_1:8_R143G,kka2_1:8_143,Kka2,kka2_1:8,P00552,1.11628,NO,143,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.525,-3.627,1.102,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.100394,0.00662247,1.11628 kka2_1:8_R143G,kka2_1:8_143,Kka2,kka2_1:8,P00552,1.11628,NO,143,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.525,-3.627,1.102,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.100394,0.00662247,1.11628 beta-lactamase_0_K30C,beta-lactamase_0_30,TEM-1,beta-lactamase_0,P62593,1.11636,NO,30,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-2.307,-5.006,2.699,,0.142,H,A,2.34,-0.65,1.491,,93.01,HBH,-2.32833,0.0500837,0.00448593,1.11636 kka2_1:2_A166F,kka2_1:2_166,Kka2,kka2_1:2,P00552,1.11636,NO,166,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.407,-4.424,2.017,,0.534,.,B,0.46,1.03,23.175,23.175,71.59,HHO,-2.421,0.295029,0.00799912,1.11636 kka2_1:2_D180S,kka2_1:2_180,Kka2,kka2_1:2,P00552,1.11639,NO,180,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.416,-2.79,0.374,,1.03,S,a,0.75,1.5,1.27,,71.59,OAO,-2.02933,0.295029,0.00756412,1.11639 kka2_1:8_R253H,kka2_1:8_253,Kka2,kka2_1:8,P00552,1.11649,NO,253,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.356,-4.521,3.165,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.100394,0.0144195,1.11649 kka2_1:8_R253H,kka2_1:8_253,Kka2,kka2_1:8,P00552,1.11649,NO,253,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.356,-4.521,3.165,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.100394,0.0144195,1.11649 WW_domain_S184Y,WW_domain_184,Yap65,WW_domain,P46937,1.1165,NO,184,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.363,-4.003,2.64,5.06696,,,,,,,,,PPO,-1.39133,0.153962,0.00231095,1.1165 kka2_1:8_D227T,kka2_1:8_227,Kka2,kka2_1:8,P00552,1.11656,NO,227,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.758,-3.153,1.395,,0.128,H,A,0.75,-0.63,0.281,,56.06,BAH,-1.43067,0.100394,0.00745029,1.11656 kka2_1:8_D227T,kka2_1:8_227,Kka2,kka2_1:8,P00552,1.11656,NO,227,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.758,-3.153,1.395,,0.128,H,A,0.75,-0.63,0.281,,56.06,BAH,-1.43067,0.100394,0.00745029,1.11656 kka2_1:2_G181E,kka2_1:2_181,Kka2,kka2_1:2,P00552,1.11658,NO,181,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-2.698,-2.628,-0.07,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.295029,0.00728319,1.11658 kka2_1:2_S11I,kka2_1:2_11,Kka2,kka2_1:2,P00552,1.11659,NO,11,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.322,-2.514,0.192,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.295029,0.00381691,1.11659 kka2_1:8_Q26P,kka2_1:8_26,Kka2,kka2_1:8,P00552,1.1166,NO,26,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.18,-2.701,0.521,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.100394,0.00708962,1.1166 kka2_1:8_Q26P,kka2_1:8_26,Kka2,kka2_1:8,P00552,1.1166,NO,26,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.18,-2.701,0.521,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.100394,0.00708962,1.1166 kka2_1:4_A65M,kka2_1:4_65,Kka2,kka2_1:4,P00552,1.11661,NO,65,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.744,-3.547,1.803,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.168804,0.00709258,1.11661 kka2_1:1_S251R,kka2_1:1_251,Kka2,kka2_1:1,P00552,1.11668,NO,251,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.636,-2.795,0.159,,0.712,H,A,0.27,-0.25,1.356,,71.59,APP,-2.09367,0.520039,0.0138916,1.11668 kka2_1:4_E231N,kka2_1:4_231,Kka2,kka2_1:4,P00552,1.11668,NO,231,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.002,-1.271,-0.731,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.168804,0.00732383,1.11668 WW_domain_A175L,WW_domain_175,Yap65,WW_domain,P46937,1.11679,NO,175,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.631,-3.321,1.69,6.69537,,,,,,6.257,,83.93,OHO,-1.30033,0.153962,0.00326874,1.11679 beta-lactamase_0_F228S,beta-lactamase_0_228,TEM-1,beta-lactamase_0,P62593,1.11682,NO,228,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-2.342,-3.492,1.15,,0.154,E,B,0.58,-0.42,15.504,15.504,63.29,HHH,-1.53033,0.0500837,0.0046669,1.11682 kka2_1:4_K175N,kka2_1:4_175,Kka2,kka2_1:4,P00552,1.11692,NO,175,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-2.897,-4.012,1.115,,0.579,H,A,1.3,0.51,15.629,15.629,71.59,HBH,-1.82333,0.168804,0.00693093,1.11692 kka2_1:8_G43F,kka2_1:8_43,Kka2,kka2_1:8,P00552,1.11694,NO,43,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.587,-4.379,2.792,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.100394,0.0071925,1.11694 kka2_1:8_G43F,kka2_1:8_43,Kka2,kka2_1:8,P00552,1.11694,NO,43,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.587,-4.379,2.792,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.100394,0.0071925,1.11694 beta-lactamase_0_E169M,beta-lactamase_0_169,TEM-1,beta-lactamase_0,P62593,1.11696,NO,169,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.23,-4.676,3.446,,0.337,,A,1.04,1,3.516,,73.08,PAH,-1.16533,0.0500837,0.00400994,1.11696 beta-lactamase_0_R92S,beta-lactamase_0_92,TEM-1,beta-lactamase_0,P62593,1.11698,NO,92,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.718,-3.47,1.752,,0.479,E,B,1.2,1.36,2.331,,65.38,BBH,-1.50367,0.0500837,0.00429626,1.11698 kka2_1:4_Q163D,kka2_1:4_163,Kka2,kka2_1:4,P00552,1.11698,NO,163,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.162,-3.807,1.645,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.168804,0.00719507,1.11698 kka2_1:4_D183N,kka2_1:4_183,Kka2,kka2_1:4,P00552,1.11703,NO,183,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.204,-2.35,1.146,,0.518,.,b,0.75,0.25,2.511,,52.27,AAH,-1.40533,0.168804,0.00426304,1.11703 kka2_1:4_E142T,kka2_1:4_142,Kka2,kka2_1:4,P00552,1.11706,NO,142,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.221,-2.837,0.616,,0.471,H,A,1.52,0.85,3.693,,65.53,HAB,-2.08033,0.168804,0.00748883,1.11706 beta-lactamase_0_A148G,beta-lactamase_0_148,TEM-1,beta-lactamase_0,P62593,1.11717,NO,148,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.757,-2.542,0.785,,0.379,H,A,0.46,-0.55,19.42,19.42,72.73,PHH,-1.40167,0.0500837,0.00547053,1.11717 kka2_1:8_G234V,kka2_1:8_234,Kka2,kka2_1:8,P00552,1.11719,NO,234,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-2.9,-2.894,-0.006,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.100394,0.00984449,1.11719 kka2_1:8_G234V,kka2_1:8_234,Kka2,kka2_1:8,P00552,1.11719,NO,234,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-2.9,-2.894,-0.006,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.100394,0.00984449,1.11719 kka2_1:1_Q27T,kka2_1:1_27,Kka2,kka2_1:1,P00552,1.11722,NO,27,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-1.659,-3.598,1.939,,0.608,.,A,0.64,0.71,0.521,,65.53,PPP,-1.90733,0.520039,0.00595365,1.11722 gb1_D266A,gb1_266,gb1,gb1,P06654,1.11723,NO,266,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.261,-3.143,1.882,,,,,,,0.638,,45.54,HAO,-1.59333,0.177985,0.00394694,1.11723 kka2_1:4_D154A,kka2_1:4_154,Kka2,kka2_1:4,P00552,1.11726,NO,154,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.876,-3.364,2.488,,0.457,,b,0.29,1.48,15.641,15.641,52.65,HAP,-1.52467,0.168804,0.00292633,1.11726 beta-lactamase_0_E62G,beta-lactamase_0_62,TEM-1,beta-lactamase_0,P62593,1.11727,NO,62,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.193,-2.548,1.355,,0.342,S,B,1.04,-0.3,5.784,,73.08,AAB,-1.417,0.0500837,0.00264802,1.11727 beta-lactamase_0_M270F,beta-lactamase_0_270,TEM-1,beta-lactamase_0,P62593,1.11729,NO,270,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.0500837,0.00767762,1.11729 kka2_1:8_L243T,kka2_1:8_243,Kka2,kka2_1:8,P00552,1.1173,NO,243,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-2.651,-2.872,0.221,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.100394,0.00884927,1.1173 kka2_1:8_L243T,kka2_1:8_243,Kka2,kka2_1:8,P00552,1.1173,NO,243,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-2.651,-2.872,0.221,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.100394,0.00884927,1.1173 beta-lactamase_0_S233G,beta-lactamase_0_233,TEM-1,beta-lactamase_0,P62593,1.11744,NO,233,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.886,-3.274,1.388,,0.016,E,B,0.27,-1.01,3.579,,77.62,BPO,-1.17267,0.0500837,0.00311415,1.11744 beta-lactamase_0_R159Q,beta-lactamase_0_159,TEM-1,beta-lactamase_0,P62593,1.11752,NO,159,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-0.94,-3.498,2.558,,0.316,,B,1.2,-0.55,1.426,,64.34,PBH,-1.011,0.0500837,0.00108472,1.11752 kka2_1:2_G55S,kka2_1:2_55,Kka2,kka2_1:2,P00552,1.11752,NO,55,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.625,-2.154,0.529,,0.517,S,b,0.75,1.19,15.753,15.753,63.64,POH,-2.05967,0.295029,0.00667877,1.11752 kka2_1:8_D250Q,kka2_1:8_250,Kka2,kka2_1:8,P00552,1.11758,NO,250,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.015,-2.867,1.852,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.100394,0.0177103,1.11758 kka2_1:8_D250Q,kka2_1:8_250,Kka2,kka2_1:8,P00552,1.11758,NO,250,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.015,-2.867,1.852,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.100394,0.0177103,1.11758 kka2_1:2_L243H,kka2_1:2_243,Kka2,kka2_1:2,P00552,1.11765,NO,243,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-2.651,-3.263,0.612,,0.277,H,A,1.59,-0.67,13.165,13.165,92.05,HHH,-2.03767,0.295029,0.00884927,1.11765 kka2_1:4_K138Y,kka2_1:4_138,Kka2,kka2_1:4,P00552,1.11767,NO,138,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-2.5,-4.407,1.907,,0.594,H,A,1.3,0.98,21.267,21.267,71.59,HBB,-2.48833,0.168804,0.00628542,1.11767 beta-lactamase_0_M67D,beta-lactamase_0_67,TEM-1,beta-lactamase_0,P62593,1.11768,NO,67,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-2.231,-3.779,1.548,,0.006,G,P,0.55,-0.81,24.165,24.165,65.03,HHP,-1.502,0.0500837,0.00409753,1.11768 beta-lactamase_0_Q267P,beta-lactamase_0_267,TEM-1,beta-lactamase_0,P62593,1.11774,NO,267,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.0500837,0.0102128,1.11774 kka2_1:8_A176F,kka2_1:8_176,Kka2,kka2_1:8,P00552,1.11777,NO,176,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.621,-4.399,2.778,,0.806,H,A,0.46,-0.03,18.904,18.904,65.53,BHB,-2.26667,0.100394,0.0083587,1.11777 kka2_1:8_A176F,kka2_1:8_176,Kka2,kka2_1:8,P00552,1.11777,NO,176,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.621,-4.399,2.778,,0.806,H,A,0.46,-0.03,18.904,18.904,65.53,BHB,-2.26667,0.100394,0.0083587,1.11777 kka2_1:2_H8T,kka2_1:2_8,Kka2,kka2_1:2,P00552,1.11778,NO,8,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-2.759,-3.343,0.584,,,,,,,,,71.59,HBH,-2.25467,0.295029,0.00256422,1.11778 kka2_1:8_E149W,kka2_1:8_149,Kka2,kka2_1:8,P00552,1.11786,NO,149,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.994,-5.569,3.575,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.100394,0.00803343,1.11786 kka2_1:8_E149W,kka2_1:8_149,Kka2,kka2_1:8,P00552,1.11786,NO,149,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.994,-5.569,3.575,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.100394,0.00803343,1.11786 gb1_T277L,gb1_277,gb1,gb1,P06654,1.11792,NO,277,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.771,-3.1,1.329,,,,,,,0.824,,35.71,BPH,-1.54833,0.177985,0.00348258,1.11792 kka2_1:2_S11R,kka2_1:2_11,Kka2,kka2_1:2,P00552,1.11792,NO,11,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.322,-3.926,1.604,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.295029,0.00381691,1.11792 beta-lactamase_0_T198S,beta-lactamase_0_198,TEM-1,beta-lactamase_0,P62593,1.11795,NO,198,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.168,-1.471,-0.697,,0.489,,B,0.22,-0.13,9.874,,73.78,HPH,-1.98767,0.0500837,0.004311,1.11795 kka2_1:8_E111K,kka2_1:8_111,Kka2,kka2_1:8,P00552,1.118,NO,111,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.28,-2.698,0.418,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.100394,0.00746789,1.118 kka2_1:8_E111K,kka2_1:8_111,Kka2,kka2_1:8,P00552,1.118,NO,111,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.28,-2.698,0.418,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.100394,0.00746789,1.118 kka2_1:8_G181W,kka2_1:8_181,Kka2,kka2_1:8,P00552,1.11801,NO,181,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-2.698,-5.561,2.863,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.100394,0.00728319,1.11801 kka2_1:8_G181W,kka2_1:8_181,Kka2,kka2_1:8,P00552,1.11801,NO,181,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-2.698,-5.561,2.863,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.100394,0.00728319,1.11801 kka2_1:8_A166L,kka2_1:8_166,Kka2,kka2_1:8,P00552,1.11804,NO,166,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.407,-3.58,1.173,,0.534,,B,1.04,1.03,13.995,13.995,71.59,HHO,-2.421,0.100394,0.00799912,1.11804 kka2_1:8_A166L,kka2_1:8_166,Kka2,kka2_1:8,P00552,1.11804,NO,166,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.407,-3.58,1.173,,0.534,,B,1.04,1.03,13.995,13.995,71.59,HHO,-2.421,0.100394,0.00799912,1.11804 beta-lactamase_0_A34V,beta-lactamase_0_34,TEM-1,beta-lactamase_0,P62593,1.11805,NO,34,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.059,-2.227,0.168,,,H,A,0.46,-0.54,3.998,,73.78,AHA,-1.74967,0.0500837,0.00407913,1.11805 beta-lactamase_0_S233Q,beta-lactamase_0_233,TEM-1,beta-lactamase_0,P62593,1.11812,NO,233,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.886,-3.939,2.053,,0.016,E,B,0.27,-1.01,3.579,,77.62,BPO,-1.17267,0.0500837,0.00311415,1.11812 kka2_1:4_G74K,kka2_1:4_74,Kka2,kka2_1:4,P00552,1.11824,NO,74,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.18,-3.609,2.429,,0.621,T,l,0.75,0.2,1.032,,64.39,POH,-1.91667,0.168804,0.00587035,1.11824 kka2_1:8_A129L,kka2_1:8_129,Kka2,kka2_1:8,P00552,1.11826,NO,129,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.656,-3.565,1.909,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.100394,0.00726862,1.11826 kka2_1:8_A129L,kka2_1:8_129,Kka2,kka2_1:8,P00552,1.11826,NO,129,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.656,-3.565,1.909,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.100394,0.00726862,1.11826 kka2_1:8_A237V,kka2_1:8_237,Kka2,kka2_1:8,P00552,1.11826,NO,237,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.12,-1.303,-0.817,,0.068,H,A,0.46,-0.71,0.449,,92.05,HHA,-2.10433,0.100394,0.012257,1.11826 kka2_1:8_A237V,kka2_1:8_237,Kka2,kka2_1:8,P00552,1.11826,NO,237,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.12,-1.303,-0.817,,0.068,H,A,0.46,-0.71,0.449,,92.05,HHA,-2.10433,0.100394,0.012257,1.11826 kka2_1:4_A176V,kka2_1:4_176,Kka2,kka2_1:4,P00552,1.11829,NO,176,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.621,-3.617,1.996,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.168804,0.0083587,1.11829 gb1_A250S,gb1_250,gb1,gb1,P06654,1.11831,NO,250,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.713,-2.983,1.27,,,,,,,3.465,,45.54,HHP,-1.74867,0.177985,0.00332003,1.11831 gb1_E268W,gb1_268,gb1,gb1,P06654,1.11831,NO,268,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.918,-5.326,3.408,,,,,,,0.637,,37.28,OAH,-1.59733,0.177985,0.00423953,1.11831 kka2_1:8_R253Y,kka2_1:8_253,Kka2,kka2_1:8,P00552,1.11833,NO,253,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.356,-4.302,2.946,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.100394,0.0144195,1.11833 kka2_1:8_R253Y,kka2_1:8_253,Kka2,kka2_1:8,P00552,1.11833,NO,253,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.356,-4.302,2.946,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.100394,0.0144195,1.11833 beta-lactamase_0_Q203I,beta-lactamase_0_203,TEM-1,beta-lactamase_0,P62593,1.1184,NO,203,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.168,-3.973,1.805,,0.47,H,A,0.64,-0.38,14.541,14.541,65.38,BPP,-1.614,0.0500837,0.00631514,1.1184 beta-lactamase_0_E164L,beta-lactamase_0_164,TEM-1,beta-lactamase_0,P62593,1.11846,NO,164,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-0.948,-3.627,2.679,,0.011,T,B,1.04,-0.4,1.011,,64.69,HAO,-1.388,0.0500837,0.00137286,1.11846 kka2_1:8_L81I,kka2_1:8_81,Kka2,kka2_1:8,P00552,1.11847,NO,81,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.427,-1.722,0.295,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.100394,0.00805839,1.11847 kka2_1:8_L81I,kka2_1:8_81,Kka2,kka2_1:8,P00552,1.11847,NO,81,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.427,-1.722,0.295,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.100394,0.00805839,1.11847 kka2_1:8_A87G,kka2_1:8_87,Kka2,kka2_1:8,P00552,1.11851,NO,87,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.917,-2.002,0.085,,1.039,S,L,0.46,1.57,16.115,16.115,65.53,AHO,-1.822,0.100394,0.00791281,1.11851 kka2_1:8_A87G,kka2_1:8_87,Kka2,kka2_1:8,P00552,1.11851,NO,87,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.917,-2.002,0.085,,1.039,S,L,0.46,1.57,16.115,16.115,65.53,AHO,-1.822,0.100394,0.00791281,1.11851 beta-lactamase_0_N130H,beta-lactamase_0_130,TEM-1,beta-lactamase_0,P62593,1.11854,NO,130,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-0.798,-4.005,3.207,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.0500837,0.000683376,1.11854 beta-lactamase_0_I280P,beta-lactamase_0_280,TEM-1,beta-lactamase_0,P62593,1.11858,NO,280,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.0500837,0.0530888,1.11858 kka2_1:2_Q4C,kka2_1:2_4,Kka2,kka2_1:2,P00552,1.11861,NO,4,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.361,-4.857,2.496,,,,,,,2.026,,71.59,APA,-1.95533,0.295029,0.00239179,1.11861 beta-lactamase_39_I171F,beta-lactamase_39_171,TEM-1,beta-lactamase_39,P62593,1.11863,NO,171,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-2.431,-3.175,0.744,,0.361,,B,0.48,0.53,16.954,16.954,77.62,HHO,-1.55533,0.0495842,0.00623355,1.11863 kka2_1:4_S114H,kka2_1:4_114,Kka2,kka2_1:4,P00552,1.11872,NO,114,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.527,-3.031,0.504,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.168804,0.00705262,1.11872 kka2_1:8_A9N,kka2_1:8_9,Kka2,kka2_1:8,P00552,1.11874,NO,9,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.079,-2.623,0.544,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.100394,0.00273264,1.11874 kka2_1:8_A9N,kka2_1:8_9,Kka2,kka2_1:8,P00552,1.11874,NO,9,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.079,-2.623,0.544,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.100394,0.00273264,1.11874 kka2_1:2_L57H,kka2_1:2_57,Kka2,kka2_1:2,P00552,1.11875,NO,57,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.898,-2.613,0.715,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.295029,0.00723769,1.11875 kka2_1:8_A176V,kka2_1:8_176,Kka2,kka2_1:8,P00552,1.11878,NO,176,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.621,-3.617,1.996,,0.806,H,A,0.46,-0.03,18.904,18.904,65.53,BHB,-2.26667,0.100394,0.0083587,1.11878 kka2_1:8_A176V,kka2_1:8_176,Kka2,kka2_1:8,P00552,1.11878,NO,176,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.621,-3.617,1.996,,0.806,H,A,0.46,-0.03,18.904,18.904,65.53,BHB,-2.26667,0.100394,0.0083587,1.11878 beta-lactamase_0_H110P,beta-lactamase_0_110,TEM-1,beta-lactamase_0,P62593,1.11881,NO,110,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-1.706,-2.996,1.29,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.0500837,0.00441499,1.11881 kka2_1:4_R122L,kka2_1:4_122,Kka2,kka2_1:4,P00552,1.11881,NO,122,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.175,-3.603,1.428,,0.487,H,A,0.16,0.26,16.436,16.436,71.59,BBH,-1.53833,0.168804,0.00736512,1.11881 kka2_1:1_A137V,kka2_1:1_137,Kka2,kka2_1:1,P00552,1.11888,NO,137,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.156,-2.289,0.133,,0.029,H,A,0.46,0.34,1.323,,63.26,PHB,-2.559,0.520039,0.00515054,1.11888 kka2_1:4_A255T,kka2_1:4_255,Kka2,kka2_1:4,P00552,1.11889,NO,255,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.715,-3.017,1.302,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.168804,0.0126809,1.11889 kka2_1:8_D82G,kka2_1:8_82,Kka2,kka2_1:8,P00552,1.11897,NO,82,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.946,-2.495,0.549,,0.341,E,b,0.29,0.52,7.463,,63.64,HAH,-1.98,0.100394,0.00637516,1.11897 kka2_1:8_D82G,kka2_1:8_82,Kka2,kka2_1:8,P00552,1.11897,NO,82,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.946,-2.495,0.549,,0.341,E,b,0.29,0.52,7.463,,63.64,HAH,-1.98,0.100394,0.00637516,1.11897 kka2_1:4_G181K,kka2_1:4_181,Kka2,kka2_1:4,P00552,1.11898,NO,181,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-2.698,-3.658,0.96,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.168804,0.00728319,1.11898 kka2_1:8_G151L,kka2_1:8_151,Kka2,kka2_1:8,P00552,1.11909,NO,151,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.873,-3.818,2.945,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.100394,0.00339918,1.11909 kka2_1:8_G151L,kka2_1:8_151,Kka2,kka2_1:8,P00552,1.11909,NO,151,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.873,-3.818,2.945,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.100394,0.00339918,1.11909 beta-lactamase_0_S201Q,beta-lactamase_0_201,TEM-1,beta-lactamase_0,P62593,1.11917,NO,201,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.183,-2.836,1.653,,0.064,H,A,0.27,-0.07,3.54,,64.69,HPB,-1.451,0.0500837,0.00198815,1.11917 beta-lactamase_0_Q203P,beta-lactamase_0_203,TEM-1,beta-lactamase_0,P62593,1.11919,NO,203,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.168,-3.941,1.773,,0.47,H,A,0.64,-0.38,14.541,14.541,65.38,BPP,-1.614,0.0500837,0.00631514,1.11919 kka2_1:8_F256W,kka2_1:8_256,Kka2,kka2_1:8,P00552,1.11923,NO,256,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.49,-2.846,1.356,,,H,A,1.62,-0.78,1.713,,53.03,HHH,-1.423,0.100394,0.0132841,1.11923 kka2_1:8_F256W,kka2_1:8_256,Kka2,kka2_1:8,P00552,1.11923,NO,256,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.49,-2.846,1.356,,,H,A,1.62,-0.78,1.713,,53.03,HHH,-1.423,0.100394,0.0132841,1.11923 PSD95pdz3_H317I,PSD95pdz3_317,PSD95pdz3,PSD95pdz3,P31016,1.1194,NO,317,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-1.627,-3.692,2.065,6.19713,,,,,25.885,,,,HBB,-1.613,0.0758425,0.00111619,1.1194 kka2_1:8_L81V,kka2_1:8_81,Kka2,kka2_1:8,P00552,1.11946,NO,81,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.427,-1.839,0.412,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.100394,0.00805839,1.11946 kka2_1:8_L81V,kka2_1:8_81,Kka2,kka2_1:8,P00552,1.11946,NO,81,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.427,-1.839,0.412,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.100394,0.00805839,1.11946 kka2_1:8_D127Q,kka2_1:8_127,Kka2,kka2_1:8,P00552,1.11947,NO,127,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.364,-3.882,2.518,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.100394,0.00660501,1.11947 kka2_1:8_D127Q,kka2_1:8_127,Kka2,kka2_1:8,P00552,1.11947,NO,127,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.364,-3.882,2.518,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.100394,0.00660501,1.11947 kka2_1:2_G10F,kka2_1:2_10,Kka2,kka2_1:2,P00552,1.11948,NO,10,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.921,-4.367,2.446,,,,,,,2.192,,71.59,HOP,-2.10733,0.295029,0.00289233,1.11948 beta-lactamase_0_K30G,beta-lactamase_0_30,TEM-1,beta-lactamase_0,P62593,1.1195,NO,30,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-2.307,-3.406,1.099,,0.142,H,A,2.34,-0.65,1.491,,93.01,HBH,-2.32833,0.0500837,0.00448593,1.1195 kka2_1:4_E182Q,kka2_1:4_182,Kka2,kka2_1:4,P00552,1.11953,NO,182,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.516,-2.606,1.09,,0.326,.,B,1.04,0.75,4.755,,65.53,OAA,-1.806,0.168804,0.00641548,1.11953 kka2_1:8_L165I,kka2_1:8_165,Kka2,kka2_1:8,P00552,1.11953,NO,165,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-2.453,-3.855,1.402,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.100394,0.00801161,1.11953 kka2_1:8_L165I,kka2_1:8_165,Kka2,kka2_1:8,P00552,1.11953,NO,165,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-2.453,-3.855,1.402,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.100394,0.00801161,1.11953 kka2_1:4_D134L,kka2_1:4_134,Kka2,kka2_1:4,P00552,1.11958,NO,134,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.969,-2.811,1.842,,0.421,B,B,0.75,0.31,0.733,,49.62,HAB,-1.057,0.168804,0.00270812,1.11958 kka2_1:2_E111A,kka2_1:2_111,Kka2,kka2_1:2,P00552,1.11959,NO,111,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.28,-2.356,0.076,,0.155,H,A,1.52,-1.14,2.792,,65.53,HAB,-2.27833,0.295029,0.00746789,1.11959 kka2_1:2_E160Q,kka2_1:2_160,Kka2,kka2_1:2,P00552,1.11965,NO,160,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.683,-3.734,2.051,,0.989,G,A,1.04,2.28,3.948,,71.59,AAA,-1.36133,0.295029,0.00935762,1.11965 kka2_1:8_P98N,kka2_1:8_98,Kka2,kka2_1:8,P00552,1.11965,NO,98,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.526,-3.852,2.326,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.100394,0.00622754,1.11965 kka2_1:8_P98N,kka2_1:8_98,Kka2,kka2_1:8,P00552,1.11965,NO,98,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.526,-3.852,2.326,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.100394,0.00622754,1.11965 beta-lactamase_0_Q86S,beta-lactamase_0_86,TEM-1,beta-lactamase_0,P62593,1.11966,NO,86,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.4,-2.711,0.311,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.0500837,0.00450027,1.11966 kka2_1:8_D183N,kka2_1:8_183,Kka2,kka2_1:8,P00552,1.11967,NO,183,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.204,-2.35,1.146,,0.518,.,b,0.75,0.25,0.347,,52.27,AAH,-1.40533,0.100394,0.00426304,1.11967 kka2_1:8_D183N,kka2_1:8_183,Kka2,kka2_1:8,P00552,1.11967,NO,183,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.204,-2.35,1.146,,0.518,.,b,0.75,0.25,0.347,,52.27,AAH,-1.40533,0.100394,0.00426304,1.11967 kka2_1:2_Q4S,kka2_1:2_4,Kka2,kka2_1:2,P00552,1.11969,NO,4,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.361,-2.105,-0.256,,,,,,,2.026,,71.59,APA,-1.95533,0.295029,0.00239179,1.11969 beta-lactamase_0_L196G,beta-lactamase_0_196,TEM-1,beta-lactamase_0,P62593,1.11979,NO,196,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-2.478,-2.91,0.432,,0.518,S,A,0.55,1.35,6.513,6.513,77.62,AHH,-1.839,0.0500837,0.00512144,1.11979 kka2_1:2_Q155G,kka2_1:2_155,Kka2,kka2_1:2,P00552,1.11979,NO,155,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.606,-2.641,0.035,,0.525,T,A,0.64,1.49,1.592,,63.64,APA,-1.726,0.295029,0.00641853,1.11979 kka2_1:2_E199K,kka2_1:2_199,Kka2,kka2_1:2,P00552,1.11982,NO,199,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.234,-3.055,0.821,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.295029,0.00854122,1.11982 kka2_1:8_L103H,kka2_1:8_103,Kka2,kka2_1:8,P00552,1.11988,NO,103,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-2.362,-4.862,2.5,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.100394,0.00574792,1.11988 kka2_1:8_L103H,kka2_1:8_103,Kka2,kka2_1:8,P00552,1.11988,NO,103,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-2.362,-4.862,2.5,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.100394,0.00574792,1.11988 kka2_1:8_R38Q,kka2_1:8_38,Kka2,kka2_1:8,P00552,1.11988,NO,38,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.207,-3.749,2.542,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.100394,0.00372499,1.11988 kka2_1:8_R38Q,kka2_1:8_38,Kka2,kka2_1:8,P00552,1.11988,NO,38,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.207,-3.749,2.542,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.100394,0.00372499,1.11988 kka2_1:4_M1T,kka2_1:4_1,Kka2,kka2_1:4,P00552,1.11991,NO,1,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-1.787,-3.152,1.365,,,,,,,1.347,,62.12,NAHH,-1.787,0.168804,0.00251939,1.11991 beta-lactamase_0_R275H,beta-lactamase_0_275,TEM-1,beta-lactamase_0,P62593,1.11993,NO,275,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.0500837,0.0141984,1.11993 kka2_1:8_G21K,kka2_1:8_21,Kka2,kka2_1:8,P00552,1.11993,NO,21,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.368,-3.662,2.294,,0.586,T,l,0.29,-0.75,4.889,,71.59,HOH,-2.10167,0.100394,0.00709648,1.11993 kka2_1:8_G21K,kka2_1:8_21,Kka2,kka2_1:8,P00552,1.11993,NO,21,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.368,-3.662,2.294,,0.586,T,l,0.29,-0.75,4.889,,71.59,HOH,-2.10167,0.100394,0.00709648,1.11993 kka2_1:8_T187S,kka2_1:8_187,Kka2,kka2_1:8,P00552,1.11993,NO,187,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.273,-2.293,1.02,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.100394,0.00693073,1.11993 kka2_1:8_T187S,kka2_1:8_187,Kka2,kka2_1:8,P00552,1.11993,NO,187,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.273,-2.293,1.02,,0.007,E,B,0.22,-0.85,1.519,,52.27,HPB,-1.06567,0.100394,0.00693073,1.11993 kka2_1:2_Q219M,kka2_1:2_219,Kka2,kka2_1:2,P00552,1.12002,NO,219,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-0.93,-4.327,3.397,,0.088,H,A,0.4,-0.85,1.917,,50,HPA,-1.05167,0.295029,0.00237913,1.12002 kka2_1:8_S204G,kka2_1:8_204,Kka2,kka2_1:8,P00552,1.12007,NO,204,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.353,-2.544,1.191,,0.144,E,A,0.27,-1.2,0.368,,65.53,HPO,-0.953333,0.100394,0.00881794,1.12007 kka2_1:8_S204G,kka2_1:8_204,Kka2,kka2_1:8,P00552,1.12007,NO,204,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.353,-2.544,1.191,,0.144,E,A,0.27,-1.2,0.368,,65.53,HPO,-0.953333,0.100394,0.00881794,1.12007 kka2_1:4_R202Q,kka2_1:4_202,Kka2,kka2_1:4,P00552,1.12011,NO,202,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.761,-2.622,0.861,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.168804,0.00696498,1.12011 beta-lactamase_0_E164Y,beta-lactamase_0_164,TEM-1,beta-lactamase_0,P62593,1.12024,NO,164,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-0.948,-4.233,3.285,,0.011,T,B,1.04,-0.4,1.011,,64.69,HAO,-1.388,0.0500837,0.00137286,1.12024 kka2_1:4_T146N,kka2_1:4_146,Kka2,kka2_1:4,P00552,1.12025,NO,146,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.978,-3.146,0.168,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.168804,0.00606474,1.12025 kka2_1:4_H139N,kka2_1:4_139,Kka2,kka2_1:4,P00552,1.12031,NO,139,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-2.809,-2.773,-0.036,,0.471,H,A,0.17,0.68,12.761,12.761,63.64,BBB,-2.22,0.168804,0.00734779,1.12031 kka2_1:8_L57I,kka2_1:8_57,Kka2,kka2_1:8,P00552,1.12041,NO,57,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.898,-2.89,0.992,,0.343,T,A,0.55,0.98,13.359,13.359,52.65,HHP,-2.20733,0.100394,0.00723769,1.12041 kka2_1:8_L57I,kka2_1:8_57,Kka2,kka2_1:8,P00552,1.12041,NO,57,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.898,-2.89,0.992,,0.343,T,A,0.55,0.98,13.359,13.359,52.65,HHP,-2.20733,0.100394,0.00723769,1.12041 kka2_1:4_G21K,kka2_1:4_21,Kka2,kka2_1:4,P00552,1.12043,NO,21,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.368,-3.662,2.294,,0.586,T,l,0.75,-0.75,3.075,,71.59,HOH,-2.10167,0.168804,0.00709648,1.12043 kka2_1:8_G10H,kka2_1:8_10,Kka2,kka2_1:8,P00552,1.12045,NO,10,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.921,-4.434,2.513,,,,,,,1.862,,71.59,HOP,-2.10733,0.100394,0.00289233,1.12045 kka2_1:8_G10H,kka2_1:8_10,Kka2,kka2_1:8,P00552,1.12045,NO,10,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.921,-4.434,2.513,,,,,,,1.862,,71.59,HOP,-2.10733,0.100394,0.00289233,1.12045 kka2_1:8_A35V,kka2_1:8_35,Kka2,kka2_1:8,P00552,1.12051,NO,35,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.127,-3.696,1.569,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.100394,0.00630016,1.12051 kka2_1:8_A35V,kka2_1:8_35,Kka2,kka2_1:8,P00552,1.12051,NO,35,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.127,-3.696,1.569,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.100394,0.00630016,1.12051 kka2_1:8_G181F,kka2_1:8_181,Kka2,kka2_1:8,P00552,1.12052,NO,181,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-2.698,-4.379,1.681,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.100394,0.00728319,1.12052 kka2_1:8_G181F,kka2_1:8_181,Kka2,kka2_1:8,P00552,1.12052,NO,181,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-2.698,-4.379,1.681,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.100394,0.00728319,1.12052 kka2_1:2_D134A,kka2_1:2_134,Kka2,kka2_1:2,P00552,1.12053,NO,134,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.969,-3.306,2.337,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.295029,0.00270812,1.12053 kka2_1:4_D180Q,kka2_1:4_180,Kka2,kka2_1:4,P00552,1.1206,NO,180,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.416,-3.007,0.591,,1.03,S,a,0.29,1.5,14.668,14.668,71.59,OAO,-2.02933,0.168804,0.00756412,1.1206 kka2_1:8_V83D,kka2_1:8_83,Kka2,kka2_1:8,P00552,1.12064,NO,83,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-2.567,-3.765,1.198,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.100394,0.00650486,1.12064 kka2_1:8_V83D,kka2_1:8_83,Kka2,kka2_1:8,P00552,1.12064,NO,83,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-2.567,-3.765,1.198,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.100394,0.00650486,1.12064 kka2_1:8_E17R,kka2_1:8_17,Kka2,kka2_1:8,P00552,1.12066,NO,17,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.154,-2.815,0.661,,0.957,T,A,1.04,0.22,31.483,31.483,63.64,HAB,-2.432,0.100394,0.00688738,1.12066 kka2_1:8_E17R,kka2_1:8_17,Kka2,kka2_1:8,P00552,1.12066,NO,17,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.154,-2.815,0.661,,0.957,T,A,1.04,0.22,31.483,31.483,63.64,HAB,-2.432,0.100394,0.00688738,1.12066 kka2_1:4_P249W,kka2_1:4_249,Kka2,kka2_1:4,P00552,1.12068,NO,249,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.867,-5.488,3.621,,0.406,.,B,0.52,-0.01,,,92.05,HOA,-1.66867,0.168804,0.011045,1.12068 beta-lactamase_0_K144V,beta-lactamase_0_144,TEM-1,beta-lactamase_0,P62593,1.12083,NO,144,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-2.388,-3.003,0.615,,0.863,H,A,2.34,1.27,5.696,,77.62,OBA,-1.904,0.0500837,0.00481141,1.12083 kka2_1:8_T125S,kka2_1:8_125,Kka2,kka2_1:8,P00552,1.12089,NO,125,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.622,-2.445,-0.177,,0.791,T,A,0.22,0.33,2.675,,92.05,BPH,-1.56933,0.100394,0.00821755,1.12089 kka2_1:8_T125S,kka2_1:8_125,Kka2,kka2_1:8,P00552,1.12089,NO,125,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.622,-2.445,-0.177,,0.791,T,A,0.22,0.33,2.675,,92.05,BPH,-1.56933,0.100394,0.00821755,1.12089 kka2_1:2_Q252R,kka2_1:2_252,Kka2,kka2_1:2,P00552,1.12098,NO,252,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.63,-2.449,-0.181,,0.906,H,A,0.64,0.35,5.613,,92.05,PPB,-2.20733,0.295029,0.0121001,1.12098 kka2_1:4_L243M,kka2_1:4_243,Kka2,kka2_1:4,P00552,1.12103,NO,243,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-2.651,-4.688,2.037,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.168804,0.00884927,1.12103 PSD95pdz3_G333Q,PSD95pdz3_333,PSD95pdz3,PSD95pdz3,P31016,1.12104,NO,333,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.008,-3.806,2.798,5.09445,,,,,48.755,,,,AOA,-1.22533,0.0758425,0.00092544,1.12104 kka2_1:8_A108C,kka2_1:8_108,Kka2,kka2_1:8,P00552,1.12106,NO,108,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.061,-5.089,3.028,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.100394,0.00751209,1.12106 kka2_1:8_A108C,kka2_1:8_108,Kka2,kka2_1:8,P00552,1.12106,NO,108,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.061,-5.089,3.028,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.100394,0.00751209,1.12106 kka2_1:8_D250P,kka2_1:8_250,Kka2,kka2_1:8,P00552,1.1211,NO,250,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.015,-3.798,2.783,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.100394,0.0177103,1.1211 kka2_1:8_D250P,kka2_1:8_250,Kka2,kka2_1:8,P00552,1.1211,NO,250,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.015,-3.798,2.783,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.100394,0.0177103,1.1211 kka2_1:8_A79V,kka2_1:8_79,Kka2,kka2_1:8,P00552,1.12113,NO,79,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.368,-2.938,0.57,,0.563,.,B,0.46,-0.43,,,71.59,HHH,-1.752,0.100394,0.00664821,1.12113 kka2_1:8_A79V,kka2_1:8_79,Kka2,kka2_1:8,P00552,1.12113,NO,79,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.368,-2.938,0.57,,0.563,.,B,0.46,-0.43,,,71.59,HHH,-1.752,0.100394,0.00664821,1.12113 kka2_1:8_A65M,kka2_1:8_65,Kka2,kka2_1:8,P00552,1.12115,NO,65,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.744,-3.547,1.803,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.100394,0.00709258,1.12115 kka2_1:8_A65M,kka2_1:8_65,Kka2,kka2_1:8,P00552,1.12115,NO,65,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.744,-3.547,1.803,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.100394,0.00709258,1.12115 kka2_1:4_Q136N,kka2_1:4_136,Kka2,kka2_1:4,P00552,1.12118,NO,136,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-3.021,-3.645,0.624,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.168804,0.00624149,1.12118 beta-lactamase_0_G226F,beta-lactamase_0_226,TEM-1,beta-lactamase_0,P62593,1.12123,NO,226,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.461,-4.428,2.967,,0.701,T,l,0.29,-0.25,23.034,23.034,74.48,HOH,-1.42933,0.0500837,0.00665294,1.12123 kka2_1:2_A255N,kka2_1:2_255,Kka2,kka2_1:2,P00552,1.1213,NO,255,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.715,-3.829,2.114,,0.466,H,A,0.46,-0.52,5.144,,65.53,HHH,-1.71267,0.295029,0.0126809,1.1213 kka2_1:8_P45D,kka2_1:8_45,Kka2,kka2_1:8,P00552,1.1213,NO,45,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.774,-3.026,1.252,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.100394,0.00590481,1.1213 kka2_1:8_P45D,kka2_1:8_45,Kka2,kka2_1:8,P00552,1.1213,NO,45,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.774,-3.026,1.252,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.100394,0.00590481,1.1213 kka2_1:2_A255H,kka2_1:2_255,Kka2,kka2_1:2,P00552,1.12132,NO,255,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.715,-3.488,1.773,,0.466,H,A,0.46,-0.52,5.144,,65.53,HHH,-1.71267,0.295029,0.0126809,1.12132 kka2_1:2_G21K,kka2_1:2_21,Kka2,kka2_1:2,P00552,1.12134,NO,21,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.368,-3.662,2.294,,0.586,T,l,0.29,-0.75,2.026,,71.59,HOH,-2.10167,0.295029,0.00709648,1.12134 kka2_1:2_T73A,kka2_1:2_73,Kka2,kka2_1:2,P00552,1.12137,NO,73,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.51,-2.502,-0.008,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.295029,0.00628605,1.12137 kka2_1:2_L94M,kka2_1:2_94,Kka2,kka2_1:2,P00552,1.12141,NO,94,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.618,-1.512,-0.106,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.295029,0.00520888,1.12141 kka2_1:8_H139R,kka2_1:8_139,Kka2,kka2_1:8,P00552,1.12141,NO,139,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-2.809,-2.657,-0.152,,0.471,H,A,0.17,0.68,28.583,28.583,63.64,BBB,-2.22,0.100394,0.00734779,1.12141 kka2_1:8_H139R,kka2_1:8_139,Kka2,kka2_1:8,P00552,1.12141,NO,139,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-2.809,-2.657,-0.152,,0.471,H,A,0.17,0.68,28.583,28.583,63.64,BBB,-2.22,0.100394,0.00734779,1.12141 kka2_1:8_T85L,kka2_1:8_85,Kka2,kka2_1:8,P00552,1.1216,NO,85,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.165,-2.782,0.617,,0.576,E,B,0.22,1.39,22.154,22.154,71.59,HPA,-2.10133,0.100394,0.00634493,1.1216 kka2_1:8_T85L,kka2_1:8_85,Kka2,kka2_1:8,P00552,1.1216,NO,85,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.165,-2.782,0.617,,0.576,E,B,0.22,1.39,22.154,22.154,71.59,HPA,-2.10133,0.100394,0.00634493,1.1216 kka2_1:1_G234S,kka2_1:1_234,Kka2,kka2_1:1,P00552,1.12164,NO,234,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-2.9,-2.468,-0.432,,0.494,H,A,0.29,-0.29,1.753,,71.59,OOA,-1.86767,0.520039,0.00984449,1.12164 beta-lactamase_0_R242A,beta-lactamase_0_242,TEM-1,beta-lactamase_0,P62593,1.12165,NO,242,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.0500837,0.00452879,1.12165 kka2_1:4_P167H,kka2_1:4_167,Kka2,kka2_1:4,P00552,1.12175,NO,167,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-2.403,-4.915,2.512,,0.18,H,A,0.52,0.75,3.6,,64.39,HOH,-2.26633,0.168804,0.00543203,1.12175 beta-lactamase_0_T112V,beta-lactamase_0_112,TEM-1,beta-lactamase_0,P62593,1.12176,NO,112,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.186,-2.929,0.743,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.0500837,0.00531334,1.12176 PSD95pdz3_E334Y,PSD95pdz3_334,PSD95pdz3,PSD95pdz3,P31016,1.12179,NO,334,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.404,-3.844,2.44,5.60175,,,,,53.09,,,,OAO,-1.14,0.0758425,0.000912998,1.12179 kka2_1:8_A255W,kka2_1:8_255,Kka2,kka2_1:8,P00552,1.12181,NO,255,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.715,-5.451,3.736,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.100394,0.0126809,1.12181 kka2_1:8_A255W,kka2_1:8_255,Kka2,kka2_1:8,P00552,1.12181,NO,255,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.715,-5.451,3.736,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.100394,0.0126809,1.12181 kka2_1:4_T125A,kka2_1:4_125,Kka2,kka2_1:4,P00552,1.12187,NO,125,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.622,-1.886,-0.736,,0.791,T,A,0.82,0.33,1.612,,92.05,BPH,-1.56933,0.168804,0.00821755,1.12187 beta-lactamase_0_L191K,beta-lactamase_0_191,TEM-1,beta-lactamase_0,P62593,1.12189,NO,191,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.087,-3.741,2.654,,,H,A,0.55,0.09,12.255,12.255,63.29,BHH,-1.445,0.0500837,0.00263549,1.12189 kka2_1:4_T51H,kka2_1:4_51,Kka2,kka2_1:4,P00552,1.12194,NO,51,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.199,-2.994,0.795,,0.05,E,B,0.82,-0.05,13.165,13.165,63.64,BPA,-1.76767,0.168804,0.00628861,1.12194 beta-lactamase_0_E238Y,beta-lactamase_0_238,TEM-1,beta-lactamase_0,P62593,1.12198,NO,238,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.0500837,0.00743256,1.12198 kka2_1:8_D180K,kka2_1:8_180,Kka2,kka2_1:8,P00552,1.12198,NO,180,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.416,-2.839,0.423,,1.03,S,a,0.75,1.5,14.668,14.668,71.59,OAO,-2.02933,0.100394,0.00756412,1.12198 kka2_1:8_D180K,kka2_1:8_180,Kka2,kka2_1:8,P00552,1.12198,NO,180,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.416,-2.839,0.423,,1.03,S,a,0.75,1.5,14.668,14.668,71.59,OAO,-2.02933,0.100394,0.00756412,1.12198 kka2_1:2_M1L,kka2_1:2_1,Kka2,kka2_1:2,P00552,1.12201,NO,1,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.787,-2.339,0.552,,,,,,,1.347,,62.12,NAHH,-1.787,0.295029,0.00251939,1.12201 beta-lactamase_0_I244T,beta-lactamase_0_244,TEM-1,beta-lactamase_0,P62593,1.12203,NO,244,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.555,-2.572,1.017,,,E,B,0.48,-0.84,1.241,,77.62,OHH,-1.385,0.0500837,0.00605379,1.12203 kka2_1:8_Q136V,kka2_1:8_136,Kka2,kka2_1:8,P00552,1.12204,NO,136,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-3.021,-3.774,0.753,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.100394,0.00624149,1.12204 kka2_1:8_Q136V,kka2_1:8_136,Kka2,kka2_1:8,P00552,1.12204,NO,136,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-3.021,-3.774,0.753,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.100394,0.00624149,1.12204 kka2_1:2_A56T,kka2_1:2_56,Kka2,kka2_1:2,P00552,1.12206,NO,56,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.083,-2.626,0.543,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.295029,0.00717715,1.12206 kka2_1:8_Q26K,kka2_1:8_26,Kka2,kka2_1:8,P00552,1.12212,NO,26,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.18,-2.687,0.507,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.100394,0.00708962,1.12212 kka2_1:8_Q26K,kka2_1:8_26,Kka2,kka2_1:8,P00552,1.12212,NO,26,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.18,-2.687,0.507,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.100394,0.00708962,1.12212 kka2_1:8_G95E,kka2_1:8_95,Kka2,kka2_1:8,P00552,1.12223,NO,95,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-2.403,-2.685,0.282,,0.126,E,B,0.75,-0.74,7.774,,71.59,HOA,-2.198,0.100394,0.00743616,1.12223 kka2_1:8_G95E,kka2_1:8_95,Kka2,kka2_1:8,P00552,1.12223,NO,95,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-2.403,-2.685,0.282,,0.126,E,B,0.75,-0.74,7.774,,71.59,HOA,-2.198,0.100394,0.00743616,1.12223 kka2_1:8_R89C,kka2_1:8_89,Kka2,kka2_1:8,P00552,1.12225,NO,89,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.548,-5.235,3.687,,0.209,E,B,1.2,1.41,25.3,25.3,64.39,OBA,-1.89867,0.100394,0.00524373,1.12225 kka2_1:8_R89C,kka2_1:8_89,Kka2,kka2_1:8,P00552,1.12225,NO,89,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.548,-5.235,3.687,,0.209,E,B,1.2,1.41,25.3,25.3,64.39,OBA,-1.89867,0.100394,0.00524373,1.12225 gb1_E268L,gb1_268,gb1,gb1,P06654,1.12227,NO,268,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.918,-3.269,1.351,,,,,,,0.637,,37.28,OAH,-1.59733,0.177985,0.00423953,1.12227 kka2_1:2_E169T,kka2_1:2_169,Kka2,kka2_1:2,P00552,1.12229,NO,169,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.996,-2.692,0.696,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.295029,0.00730086,1.12229 PSD95pdz3_I338V,PSD95pdz3_338,PSD95pdz3,PSD95pdz3,P31016,1.1223,NO,338,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.63,-2.085,0.455,5.45113,,,,,13.0087,,,,HHP,-1.55767,0.0758425,0.000862587,1.1223 kka2_1:8_I221V,kka2_1:8_221,Kka2,kka2_1:8,P00552,1.12233,NO,221,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.739,-2.261,0.522,,,H,A,1.52,-1.15,1.599,,71.59,AHH,-1.08367,0.100394,0.00945908,1.12233 kka2_1:8_I221V,kka2_1:8_221,Kka2,kka2_1:8,P00552,1.12233,NO,221,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.739,-2.261,0.522,,,H,A,1.52,-1.15,1.599,,71.59,AHH,-1.08367,0.100394,0.00945908,1.12233 gb1_D273W,gb1_273,gb1,gb1,P06654,1.12235,NO,273,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.998,-5.365,3.367,,,,,,,3.514,3.514,37.28,AAH,-1.72767,0.177985,0.00318903,1.12235 PSD95pdz3_G364Y,PSD95pdz3_364,PSD95pdz3,PSD95pdz3,P31016,1.12238,NO,364,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.008,-4.069,3.061,5.53299,,,,,21.28,,,,POH,-1.33667,0.0758425,0.00050942,1.12238 kka2_1:8_D238H,kka2_1:8_238,Kka2,kka2_1:8,P00552,1.12241,NO,238,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.83,-4.728,1.898,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.100394,0.0113863,1.12241 kka2_1:8_D238H,kka2_1:8_238,Kka2,kka2_1:8,P00552,1.12241,NO,238,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.83,-4.728,1.898,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.100394,0.0113863,1.12241 gb1_D273K,gb1_273,gb1,gb1,P06654,1.12242,NO,273,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.998,-2.326,0.328,,,,,,,3.514,3.514,37.28,AAH,-1.72767,0.177985,0.00318903,1.12242 beta-lactamase_0_F228A,beta-lactamase_0_228,TEM-1,beta-lactamase_0,P62593,1.12245,NO,228,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-2.342,-2.562,0.22,,0.154,E,B,0.58,-0.42,15.504,15.504,63.29,HHH,-1.53033,0.0500837,0.0046669,1.12245 kka2_1:4_S54K,kka2_1:4_54,Kka2,kka2_1:4,P00552,1.1225,NO,54,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.471,-3.67,1.199,,0.408,S,b,0.27,1.01,17.332,17.332,71.59,HPO,-2.259,0.168804,0.00782867,1.1225 kka2_1:8_Q4C,kka2_1:8_4,Kka2,kka2_1:8,P00552,1.12254,NO,4,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.361,-4.857,2.496,,,,,,,2.026,,71.59,APA,-1.95533,0.100394,0.00239179,1.12254 kka2_1:8_Q4C,kka2_1:8_4,Kka2,kka2_1:8,P00552,1.12254,NO,4,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.361,-4.857,2.496,,,,,,,2.026,,71.59,APA,-1.95533,0.100394,0.00239179,1.12254 kka2_1:8_T73F,kka2_1:8_73,Kka2,kka2_1:8,P00552,1.12254,NO,73,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.51,-4.242,1.732,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.100394,0.00628605,1.12254 kka2_1:8_T73F,kka2_1:8_73,Kka2,kka2_1:8,P00552,1.12254,NO,73,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.51,-4.242,1.732,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.100394,0.00628605,1.12254 PSD95pdz3_T321N,PSD95pdz3_321,PSD95pdz3,PSD95pdz3,P31016,1.12258,NO,321,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.391,-3.13,1.739,5.19953,,,,,20.3371,,,,PPO,-1.306,0.0758425,0.00106992,1.12258 beta-lactamase_0_A230I,beta-lactamase_0_230,TEM-1,beta-lactamase_0,P62593,1.1226,NO,230,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.154,-3.843,2.689,,0.01,E,B,0.46,-1.17,2.179,,50,HHA,-1.079,0.0500837,0.00516841,1.1226 kka2_1:2_T225W,kka2_1:2_225,Kka2,kka2_1:2,P00552,1.12264,NO,225,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.393,-5.412,3.019,,0.036,H,A,0.22,-1.22,4.554,,63.64,HPB,-1.58733,0.295029,0.0113598,1.12264 kka2_1:8_G55D,kka2_1:8_55,Kka2,kka2_1:8,P00552,1.12272,NO,55,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.625,-2.304,0.679,,0.517,S,b,0.29,1.19,8.881,,63.64,POH,-2.05967,0.100394,0.00667877,1.12272 kka2_1:8_G55D,kka2_1:8_55,Kka2,kka2_1:8,P00552,1.12272,NO,55,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.625,-2.304,0.679,,0.517,S,b,0.29,1.19,8.881,,63.64,POH,-2.05967,0.100394,0.00667877,1.12272 kka2_1:8_Q27A,kka2_1:8_27,Kka2,kka2_1:8,P00552,1.1228,NO,27,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-1.659,-3.31,1.651,,0.608,.,A,0.64,0.71,3.919,,65.53,PPP,-1.90733,0.100394,0.00595365,1.1228 kka2_1:8_Q27A,kka2_1:8_27,Kka2,kka2_1:8,P00552,1.1228,NO,27,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-1.659,-3.31,1.651,,0.608,.,A,0.64,0.71,3.919,,65.53,PPP,-1.90733,0.100394,0.00595365,1.1228 beta-lactamase_0_T147M,beta-lactamase_0_147,TEM-1,beta-lactamase_0,P62593,1.12285,NO,147,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.149,-4.573,3.424,,0.281,H,A,0.22,-0.68,3.487,,64.34,HPH,-1.456,0.0500837,0.00226017,1.12285 kka2_1:4_A87L,kka2_1:4_87,Kka2,kka2_1:4,P00552,1.12292,NO,87,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.917,-3.08,1.163,,1.039,S,L,0.46,1.57,22.675,22.675,65.53,AHO,-1.822,0.168804,0.00791281,1.12292 kka2_1:8_G88T,kka2_1:8_88,Kka2,kka2_1:8,P00552,1.12298,NO,88,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.689,-3.065,1.376,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.100394,0.00685559,1.12298 kka2_1:8_G88T,kka2_1:8_88,Kka2,kka2_1:8,P00552,1.12298,NO,88,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.689,-3.065,1.376,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.100394,0.00685559,1.12298 kka2_1:8_H8N,kka2_1:8_8,Kka2,kka2_1:8,P00552,1.12299,NO,8,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-2.759,-3.586,0.827,,,,,,,,,71.59,HBH,-2.25467,0.100394,0.00256422,1.12299 kka2_1:8_H8N,kka2_1:8_8,Kka2,kka2_1:8,P00552,1.12299,NO,8,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-2.759,-3.586,0.827,,,,,,,,,71.59,HBH,-2.25467,0.100394,0.00256422,1.12299 kka2_1:4_D156C,kka2_1:4_156,Kka2,kka2_1:4,P00552,1.12305,NO,156,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.696,-3.452,1.756,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.168804,0.00926998,1.12305 gb1_A250M,gb1_250,gb1,gb1,P06654,1.1231,NO,250,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.713,-4.424,2.711,,,,,,,3.465,,45.54,HHP,-1.74867,0.177985,0.00332003,1.1231 beta-lactamase_0_L136I,beta-lactamase_0_136,TEM-1,beta-lactamase_0,P62593,1.12311,NO,136,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.232,-1.874,0.642,,,H,A,0.55,-0.34,0.648,,48.95,HHH,-1.088,0.0500837,0.00442304,1.12311 kka2_1:8_P167H,kka2_1:8_167,Kka2,kka2_1:8,P00552,1.12312,NO,167,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-2.403,-4.915,2.512,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.100394,0.00543203,1.12312 kka2_1:8_P167H,kka2_1:8_167,Kka2,kka2_1:8,P00552,1.12312,NO,167,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-2.403,-4.915,2.512,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.100394,0.00543203,1.12312 kka2_1:2_K175Q,kka2_1:2_175,Kka2,kka2_1:2,P00552,1.12313,NO,175,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-2.897,-2.736,-0.161,,0.579,H,A,1.3,0.51,15.629,15.629,71.59,HBH,-1.82333,0.295029,0.00693093,1.12313 kka2_1:8_G234P,kka2_1:8_234,Kka2,kka2_1:8,P00552,1.12314,NO,234,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-2.9,-2.731,-0.169,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.100394,0.00984449,1.12314 kka2_1:8_G234P,kka2_1:8_234,Kka2,kka2_1:8,P00552,1.12314,NO,234,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-2.9,-2.731,-0.169,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.100394,0.00984449,1.12314 beta-lactamase_0_Y95G,beta-lactamase_0_95,TEM-1,beta-lactamase_0,P62593,1.12317,NO,95,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-1.715,-3.781,2.066,,0.122,,b,0.21,-0.37,2.914,,77.62,BHP,-2.16167,0.0500837,0.00479449,1.12317 beta-lactamase_0_I280Q,beta-lactamase_0_280,TEM-1,beta-lactamase_0,P62593,1.12325,NO,280,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.0500837,0.0530888,1.12325 gb1_E268Q,gb1_268,gb1,gb1,P06654,1.12325,NO,268,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.918,-3.476,1.558,,,,,,,0.637,,37.28,OAH,-1.59733,0.177985,0.00423953,1.12325 beta-lactamase_0_G281A,beta-lactamase_0_281,TEM-1,beta-lactamase_0,P62593,1.12338,NO,281,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.0500837,0.0406482,1.12338 beta-lactamase_0_A77S,beta-lactamase_0_77,TEM-1,beta-lactamase_0,P62593,1.12346,NO,77,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.234,-2.62,1.386,,0.039,H,A,0.46,-0.56,2.591,,64.34,OHH,-1.294,0.0500837,0.00282362,1.12346 kka2_1:8_D154R,kka2_1:8_154,Kka2,kka2_1:8,P00552,1.12348,NO,154,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.876,-3.899,3.023,,0.457,,b,0.29,1.48,0.844,,52.65,HAP,-1.52467,0.100394,0.00292633,1.12348 kka2_1:8_D154R,kka2_1:8_154,Kka2,kka2_1:8,P00552,1.12348,NO,154,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.876,-3.899,3.023,,0.457,,b,0.29,1.48,0.844,,52.65,HAP,-1.52467,0.100394,0.00292633,1.12348 beta-lactamase_0_N274D,beta-lactamase_0_274,TEM-1,beta-lactamase_0,P62593,1.12354,NO,274,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-2.082,,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.0500837,0.0110418,1.12354 beta-lactamase_0_D212N,beta-lactamase_0_212,TEM-1,beta-lactamase_0,P62593,1.12358,NO,212,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.624,-1.899,0.275,,0.037,,b,0.75,-0.58,3.34,,74.48,HAB,-1.77667,0.0500837,0.00644302,1.12358 kka2_1:2_S114T,kka2_1:2_114,Kka2,kka2_1:2,P00552,1.12359,NO,114,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.527,-2.564,0.037,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.295029,0.00705262,1.12359 kka2_1:8_W236M,kka2_1:8_236,Kka2,kka2_1:8,P00552,1.12361,NO,236,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-1.363,-4.508,3.145,,0.303,H,A,1.51,-0.76,1.87,,48.48,AHH,-1.81267,0.100394,0.0088796,1.12361 kka2_1:8_W236M,kka2_1:8_236,Kka2,kka2_1:8,P00552,1.12361,NO,236,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-1.363,-4.508,3.145,,0.303,H,A,1.51,-0.76,1.87,,48.48,AHH,-1.81267,0.100394,0.0088796,1.12361 kka2_1:8_W24Y,kka2_1:8_24,Kka2,kka2_1:8,P00552,1.12361,NO,24,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-1.779,-3.045,1.266,,0.477,E,B,1.51,-0.21,2.503,,56.06,AHH,-2.24467,0.100394,0.00631564,1.12361 kka2_1:8_W24Y,kka2_1:8_24,Kka2,kka2_1:8,P00552,1.12361,NO,24,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-1.779,-3.045,1.266,,0.477,E,B,1.51,-0.21,2.503,,56.06,AHH,-2.24467,0.100394,0.00631564,1.12361 kka2_1:8_D180H,kka2_1:8_180,Kka2,kka2_1:8,P00552,1.12363,NO,180,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.416,-3.405,0.989,,1.03,S,a,0.75,1.5,14.668,14.668,71.59,OAO,-2.02933,0.100394,0.00756412,1.12363 kka2_1:8_D180H,kka2_1:8_180,Kka2,kka2_1:8,P00552,1.12363,NO,180,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.416,-3.405,0.989,,1.03,S,a,0.75,1.5,14.668,14.668,71.59,OAO,-2.02933,0.100394,0.00756412,1.12363 kka2_1:8_H106P,kka2_1:8_106,Kka2,kka2_1:8,P00552,1.12368,NO,106,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-3.13,-2.907,-0.223,,1.065,,a,0.87,-0.95,15.956,15.956,71.59,PBH,-2.10433,0.100394,0.00730778,1.12368 kka2_1:8_H106P,kka2_1:8_106,Kka2,kka2_1:8,P00552,1.12368,NO,106,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-3.13,-2.907,-0.223,,1.065,,a,0.87,-0.95,15.956,15.956,71.59,PBH,-2.10433,0.100394,0.00730778,1.12368 beta-lactamase_0_T112M,beta-lactamase_0_112,TEM-1,beta-lactamase_0,P62593,1.12371,NO,112,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.186,-4.812,2.626,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.0500837,0.00531334,1.12371 beta-lactamase_0_L100R,beta-lactamase_0_100,TEM-1,beta-lactamase_0,P62593,1.12373,NO,100,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.218,-4.123,2.905,,0.343,,B,0.55,0.13,1.373,,63.29,AHH,-1.23467,0.0500837,0.00413885,1.12373 kka2_1:2_A65Q,kka2_1:2_65,Kka2,kka2_1:2,P00552,1.12376,NO,65,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.744,-2.822,1.078,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.295029,0.00709258,1.12376 kka2_1:4_I196L,kka2_1:4_196,Kka2,kka2_1:4,P00552,1.12376,NO,196,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-2.115,-1.762,-0.353,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.168804,0.0107273,1.12376 kka2_1:8_D134L,kka2_1:8_134,Kka2,kka2_1:8,P00552,1.1238,NO,134,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.969,-2.811,1.842,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.100394,0.00270812,1.1238 kka2_1:8_D134L,kka2_1:8_134,Kka2,kka2_1:8,P00552,1.1238,NO,134,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.969,-2.811,1.842,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.100394,0.00270812,1.1238 kka2_1:8_L103K,kka2_1:8_103,Kka2,kka2_1:8,P00552,1.1238,NO,103,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-2.362,-3.65,1.288,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.100394,0.00574792,1.1238 kka2_1:8_L103K,kka2_1:8_103,Kka2,kka2_1:8,P00552,1.1238,NO,103,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-2.362,-3.65,1.288,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.100394,0.00574792,1.1238 kka2_1:8_Q26Y,kka2_1:8_26,Kka2,kka2_1:8,P00552,1.12383,NO,26,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.18,-4.333,2.153,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.100394,0.00708962,1.12383 kka2_1:8_Q26Y,kka2_1:8_26,Kka2,kka2_1:8,P00552,1.12383,NO,26,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.18,-4.333,2.153,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.100394,0.00708962,1.12383 kka2_1:8_A229H,kka2_1:8_229,Kka2,kka2_1:8,P00552,1.12385,NO,229,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.739,-3.451,1.712,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.100394,0.00942138,1.12385 kka2_1:8_A229H,kka2_1:8_229,Kka2,kka2_1:8,P00552,1.12385,NO,229,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.739,-3.451,1.712,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.100394,0.00942138,1.12385 kka2_1:8_A87Q,kka2_1:8_87,Kka2,kka2_1:8,P00552,1.12385,NO,87,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.917,-3.008,1.091,,1.039,S,L,0.46,1.57,16.115,16.115,65.53,AHO,-1.822,0.100394,0.00791281,1.12385 kka2_1:8_A87Q,kka2_1:8_87,Kka2,kka2_1:8,P00552,1.12385,NO,87,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.917,-3.008,1.091,,1.039,S,L,0.46,1.57,16.115,16.115,65.53,AHO,-1.822,0.100394,0.00791281,1.12385 beta-lactamase_0_S104H,beta-lactamase_0_104,TEM-1,beta-lactamase_0,P62593,1.12387,NO,104,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.015,-4.582,3.567,,0.04,,b,0.27,0.57,1.148,,63.29,HPO,-1.05267,0.0500837,0.00218083,1.12387 kka2_1:8_A137L,kka2_1:8_137,Kka2,kka2_1:8,P00552,1.12387,NO,137,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.156,-1.375,-0.781,,0.029,H,A,1.04,0.34,2.886,,63.26,PHB,-2.559,0.100394,0.00515054,1.12387 kka2_1:8_A137L,kka2_1:8_137,Kka2,kka2_1:8,P00552,1.12387,NO,137,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.156,-1.375,-0.781,,0.029,H,A,1.04,0.34,2.886,,63.26,PHB,-2.559,0.100394,0.00515054,1.12387 kka2_1:2_A191Y,kka2_1:2_191,Kka2,kka2_1:2,P00552,1.12391,NO,191,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.831,-4.254,3.423,,,.,b,0.46,-0.94,2.046,,50,AHO,-0.868667,0.295029,0.00338807,1.12391 kka2_1:8_A56V,kka2_1:8_56,Kka2,kka2_1:8,P00552,1.12394,NO,56,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.083,-2.653,0.57,,0.796,T,A,0.46,1.39,10.511,,71.59,OHH,-1.86867,0.100394,0.00717715,1.12394 kka2_1:8_A56V,kka2_1:8_56,Kka2,kka2_1:8,P00552,1.12394,NO,56,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.083,-2.653,0.57,,0.796,T,A,0.46,1.39,10.511,,71.59,OHH,-1.86867,0.100394,0.00717715,1.12394 kka2_1:8_H8T,kka2_1:8_8,Kka2,kka2_1:8,P00552,1.124,NO,8,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-2.759,-3.343,0.584,,,,,,,,,71.59,HBH,-2.25467,0.100394,0.00256422,1.124 kka2_1:8_H8T,kka2_1:8_8,Kka2,kka2_1:8,P00552,1.124,NO,8,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-2.759,-3.343,0.584,,,,,,,,,71.59,HBH,-2.25467,0.100394,0.00256422,1.124 kka2_1:4_Q27D,kka2_1:4_27,Kka2,kka2_1:4,P00552,1.12403,NO,27,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-1.659,-1.745,0.086,,0.608,,A,0.4,0.71,1.498,,65.53,PPP,-1.90733,0.168804,0.00595365,1.12403 kka2_1:4_Q163H,kka2_1:4_163,Kka2,kka2_1:4,P00552,1.12408,NO,163,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.162,-4.775,2.613,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.168804,0.00719507,1.12408 kka2_1:8_S54K,kka2_1:8_54,Kka2,kka2_1:8,P00552,1.12409,NO,54,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.471,-3.67,1.199,,0.408,S,b,0.77,1.01,13.679,13.679,71.59,HPO,-2.259,0.100394,0.00782867,1.12409 kka2_1:8_S54K,kka2_1:8_54,Kka2,kka2_1:8,P00552,1.12409,NO,54,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.471,-3.67,1.199,,0.408,S,b,0.77,1.01,13.679,13.679,71.59,HPO,-2.259,0.100394,0.00782867,1.12409 kka2_1:8_H8I,kka2_1:8_8,Kka2,kka2_1:8,P00552,1.12421,NO,8,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-2.759,-2.602,-0.157,,,,,,,,,71.59,HBH,-2.25467,0.100394,0.00256422,1.12421 kka2_1:8_H8I,kka2_1:8_8,Kka2,kka2_1:8,P00552,1.12421,NO,8,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-2.759,-2.602,-0.157,,,,,,,,,71.59,HBH,-2.25467,0.100394,0.00256422,1.12421 kka2_1:4_A168D,kka2_1:4_168,Kka2,kka2_1:4,P00552,1.12435,NO,168,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.989,-2.545,0.556,,0.67,H,A,0.46,0.15,,,64.39,OHA,-2.12933,0.168804,0.00806773,1.12435 beta-lactamase_0_Q267N,beta-lactamase_0_267,TEM-1,beta-lactamase_0,P62593,1.12439,NO,267,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.0500837,0.0102128,1.12439 kka2_1:2_T73R,kka2_1:2_73,Kka2,kka2_1:2,P00552,1.12443,NO,73,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.51,-2.766,0.256,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.295029,0.00628605,1.12443 beta-lactamase_39_E26G,beta-lactamase_39_26,TEM-1,beta-lactamase_39,P62593,1.12445,NO,26,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.454,-2.639,0.185,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.0495842,0.00297948,1.12445 beta-lactamase_0_P224M,beta-lactamase_0_224,TEM-1,beta-lactamase_0,P62593,1.12452,NO,224,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.893,-4.704,3.811,,0.383,,B,0.52,-0.3,3.587,,74.48,HOH,-1.26433,0.0500837,0.00189564,1.12452 kka2_1:8_Y22F,kka2_1:8_22,Kka2,kka2_1:8,P00552,1.12453,NO,22,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-1.583,-3.718,2.135,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.100394,0.00598977,1.12453 kka2_1:8_Y22F,kka2_1:8_22,Kka2,kka2_1:8,P00552,1.12453,NO,22,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-1.583,-3.718,2.135,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.100394,0.00598977,1.12453 kka2_1:2_A108S,kka2_1:2_108,Kka2,kka2_1:2,P00552,1.12454,NO,108,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.061,-2.146,0.085,,0.243,.,B,0.46,-1.34,2.462,,71.59,HHO,-1.57033,0.295029,0.00751209,1.12454 beta-lactamase_0_L135V,beta-lactamase_0_135,TEM-1,beta-lactamase_0,P62593,1.12455,NO,135,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.002,-2.8,1.798,,0.117,H,A,0.55,-0.58,0.705,,43.71,PHH,-1.03767,0.0500837,0.00244423,1.12455 kka2_1:4_V80S,kka2_1:4_80,Kka2,kka2_1:4,P00552,1.12456,NO,80,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.144,-3.612,2.468,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.168804,0.00488211,1.12456 kka2_1:2_C31R,kka2_1:2_31,Kka2,kka2_1:2,P00552,1.12457,NO,31,C,R,CR,Special,PositiveCharge,5.07,6.34148,1.27148,180,121,174,53,108.5,173.4,64.9,-2.246,-1.901,-0.345,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.295029,0.00681582,1.12457 beta-lactamase_0_S104C,beta-lactamase_0_104,TEM-1,beta-lactamase_0,P62593,1.12461,NO,104,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.015,-2.945,1.93,,0.04,,b,0.27,0.57,1.148,,63.29,HPO,-1.05267,0.0500837,0.00218083,1.12461 kka2_1:4_D52L,kka2_1:4_52,Kka2,kka2_1:4,P00552,1.12462,NO,52,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.271,-3.655,1.384,,0.22,E,B,0.75,0.8,0.349,,71.59,PAH,-2.38367,0.168804,0.00175694,1.12462 kka2_1:2_V83F,kka2_1:2_83,Kka2,kka2_1:2,P00552,1.12472,NO,83,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-2.567,-2.568,0.001,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.295029,0.00650486,1.12472 kka2_1:8_L47I,kka2_1:8_47,Kka2,kka2_1:8,P00552,1.12472,NO,47,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.265,-3.255,1.99,,0.139,E,B,1.59,-0.86,5.086,,63.26,HHH,-1.77933,0.100394,0.00509386,1.12472 kka2_1:8_L47I,kka2_1:8_47,Kka2,kka2_1:8,P00552,1.12472,NO,47,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.265,-3.255,1.99,,0.139,E,B,1.59,-0.86,5.086,,63.26,HHH,-1.77933,0.100394,0.00509386,1.12472 gb1_T251W,gb1_251,gb1,gb1,P06654,1.12474,NO,251,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.794,-5.098,3.304,,,,,,,3.514,3.514,37.28,HPH,-1.56067,0.177985,0.00232932,1.12474 kka2_1:4_G164E,kka2_1:4_164,Kka2,kka2_1:4,P00552,1.12478,NO,164,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.869,-3.557,2.688,,0.862,T,l,0.75,1.45,1.539,,64.39,POH,-1.828,0.168804,0.00442091,1.12478 PSD95pdz3_T321Q,PSD95pdz3_321,PSD95pdz3,PSD95pdz3,P31016,1.12496,NO,321,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.391,-3.581,2.19,5.19953,,,,,20.3371,,,,PPO,-1.306,0.0758425,0.00106992,1.12496 beta-lactamase_0_L188T,beta-lactamase_0_188,TEM-1,beta-lactamase_0,P62593,1.12497,NO,188,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.166,-3.522,2.356,,,H,A,0.55,-0.3,2.739,,60.14,PHB,-1.47033,0.0500837,0.00295687,1.12497 kka2_1:2_A108N,kka2_1:2_108,Kka2,kka2_1:2,P00552,1.12497,NO,108,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.061,-3.827,1.766,,0.243,.,B,0.46,-1.34,2.462,,71.59,HHO,-1.57033,0.295029,0.00751209,1.12497 beta-lactamase_0_Q267L,beta-lactamase_0_267,TEM-1,beta-lactamase_0,P62593,1.12503,NO,267,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.0500837,0.0102128,1.12503 beta-lactamase_0_V106Q,beta-lactamase_0_106,TEM-1,beta-lactamase_0,P62593,1.12505,NO,106,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.218,-4.248,3.03,,0.258,T,A,0.44,0.24,0.952,,72.73,OHP,-1.04933,0.0500837,0.00304168,1.12505 beta-lactamase_0_I245S,beta-lactamase_0_245,TEM-1,beta-lactamase_0,P62593,1.12506,NO,245,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.0500837,0.00391032,1.12506 kka2_1:8_D250V,kka2_1:8_250,Kka2,kka2_1:8,P00552,1.12507,NO,250,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.015,-3.813,2.798,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.100394,0.0177103,1.12507 kka2_1:8_D250V,kka2_1:8_250,Kka2,kka2_1:8,P00552,1.12507,NO,250,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.015,-3.813,2.798,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.100394,0.0177103,1.12507 beta-lactamase_0_S201G,beta-lactamase_0_201,TEM-1,beta-lactamase_0,P62593,1.12508,NO,201,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-1.183,-2.39,1.207,,0.064,H,A,0.27,-0.07,3.54,,64.69,HPB,-1.451,0.0500837,0.00198815,1.12508 beta-lactamase_0_F149Q,beta-lactamase_0_149,TEM-1,beta-lactamase_0,P62593,1.12515,NO,149,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.299,-4.204,2.905,,0.195,H,A,0.58,0.11,3.518,,63.99,HHH,-1.46067,0.0500837,0.00418462,1.12515 beta-lactamase_0_R275S,beta-lactamase_0_275,TEM-1,beta-lactamase_0,P62593,1.12516,NO,275,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.0500837,0.0141984,1.12516 PSD95pdz3_D366Y,PSD95pdz3_366,PSD95pdz3,PSD95pdz3,P31016,1.1252,NO,366,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.264,-4.069,2.805,5.55684,,,,,20.2375,,,,HAH,-1.401,0.0758425,0.000481272,1.1252 kka2_1:4_S114N,kka2_1:4_114,Kka2,kka2_1:4,P00552,1.12523,NO,114,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.527,-3.164,0.637,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.168804,0.00705262,1.12523 kka2_1:8_P109K,kka2_1:8_109,Kka2,kka2_1:8,P00552,1.12524,NO,109,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.412,-3.629,2.217,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.100394,0.0070929,1.12524 kka2_1:8_P109K,kka2_1:8_109,Kka2,kka2_1:8,P00552,1.12524,NO,109,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.412,-3.629,2.217,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.100394,0.0070929,1.12524 kka2_1:8_G74A,kka2_1:8_74,Kka2,kka2_1:8,P00552,1.12527,NO,74,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.18,-3.17,1.99,,0.621,T,l,0.29,0.2,2.014,,64.39,POH,-1.91667,0.100394,0.00587035,1.12527 kka2_1:8_G74A,kka2_1:8_74,Kka2,kka2_1:8,P00552,1.12527,NO,74,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.18,-3.17,1.99,,0.621,T,l,0.29,0.2,2.014,,64.39,POH,-1.91667,0.100394,0.00587035,1.12527 beta-lactamase_0_T138L,beta-lactamase_0_138,TEM-1,beta-lactamase_0,P62593,1.12533,NO,138,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.506,-3.638,1.132,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.0500837,0.00487868,1.12533 beta-lactamase_0_G39R,beta-lactamase_0_39,TEM-1,beta-lactamase_0,P62593,1.12534,NO,39,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.864,-3.077,1.213,,0.701,T,L,0.29,0.47,4.111,,77.62,HOH,-1.53633,0.0500837,0.00487611,1.12534 beta-lactamase_0_K30R,beta-lactamase_0_30,TEM-1,beta-lactamase_0,P62593,1.12534,NO,30,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-2.307,-2.265,-0.042,,0.142,H,A,2.34,-0.65,1.491,,93.01,HBH,-2.32833,0.0500837,0.00448593,1.12534 beta-lactamase_0_K53N,beta-lactamase_0_53,TEM-1,beta-lactamase_0,P62593,1.12534,NO,53,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-2.313,-3.809,1.496,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.0500837,0.00383383,1.12534 kka2_1:8_R145Q,kka2_1:8_145,Kka2,kka2_1:8,P00552,1.12535,NO,145,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.804,-2.583,0.779,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.100394,0.00846663,1.12535 kka2_1:8_R145Q,kka2_1:8_145,Kka2,kka2_1:8,P00552,1.12535,NO,145,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.804,-2.583,0.779,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.100394,0.00846663,1.12535 gb1_D273H,gb1_273,gb1,gb1,P06654,1.1254,NO,273,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.998,-4.44,2.442,,,,,,,3.514,3.514,37.28,AAH,-1.72767,0.177985,0.00318903,1.1254 kka2_1:2_G10N,kka2_1:2_10,Kka2,kka2_1:2,P00552,1.12542,NO,10,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.921,-2.575,0.654,,,,,,,2.192,,71.59,HOP,-2.10733,0.295029,0.00289233,1.12542 kka2_1:8_R173H,kka2_1:8_173,Kka2,kka2_1:8,P00552,1.12546,NO,173,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.407,-4.589,2.182,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.100394,0.00784999,1.12546 kka2_1:8_R173H,kka2_1:8_173,Kka2,kka2_1:8,P00552,1.12546,NO,173,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.407,-4.589,2.182,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.100394,0.00784999,1.12546 kka2_1:4_A64M,kka2_1:4_64,Kka2,kka2_1:4,P00552,1.1255,NO,64,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.496,-4.439,2.943,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.168804,0.00705578,1.1255 kka2_1:4_K138L,kka2_1:4_138,Kka2,kka2_1:4,P00552,1.12551,NO,138,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-2.5,-3.647,1.147,,0.594,H,A,1.3,0.98,21.267,21.267,71.59,HBB,-2.48833,0.168804,0.00628542,1.12551 kka2_1:8_I254T,kka2_1:8_254,Kka2,kka2_1:8,P00552,1.12553,NO,254,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.933,-3.596,1.663,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.100394,0.0132375,1.12553 kka2_1:8_I254T,kka2_1:8_254,Kka2,kka2_1:8,P00552,1.12553,NO,254,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.933,-3.596,1.663,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.100394,0.0132375,1.12553 kka2_1:4_E160G,kka2_1:4_160,Kka2,kka2_1:4,P00552,1.12559,NO,160,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.683,-3.367,1.684,,0.989,G,A,1.04,2.28,2.531,,71.59,AAA,-1.36133,0.168804,0.00935762,1.12559 kka2_1:2_P249R,kka2_1:2_249,Kka2,kka2_1:2,P00552,1.1256,NO,249,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.867,-3.291,1.424,,0.406,.,B,0.52,-0.01,0.76,,92.05,HOA,-1.66867,0.295029,0.011045,1.1256 kka2_1:8_A172T,kka2_1:8_172,Kka2,kka2_1:8,P00552,1.1256,NO,172,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.757,-2.834,1.077,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.100394,0.0079265,1.1256 kka2_1:8_A172T,kka2_1:8_172,Kka2,kka2_1:8,P00552,1.1256,NO,172,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.757,-2.834,1.077,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.100394,0.0079265,1.1256 PSD95pdz3_I389R,PSD95pdz3_389,PSD95pdz3,PSD95pdz3,P31016,1.12562,NO,389,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.628,-3.935,2.307,5.15116,,,,,14.8038,1.498,,87.71,HHH,-1.52167,0.0758425,0.00148097,1.12562 beta-lactamase_0_S283Y,beta-lactamase_0_283,TEM-1,beta-lactamase_0,P62593,1.12563,NO,283,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.0500837,0.0429138,1.12563 kka2_1:4_E169N,kka2_1:4_169,Kka2,kka2_1:4,P00552,1.12563,NO,169,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.996,-3.126,1.13,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.168804,0.00730086,1.12563 beta-lactamase_0_P165V,beta-lactamase_0_165,TEM-1,beta-lactamase_0,P62593,1.12564,NO,165,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.373,-3.333,1.96,,0.203,T,A,0.52,-0.31,3.242,,73.78,AOA,-1.359,0.0500837,0.00549538,1.12564 kka2_1:4_Q42M,kka2_1:4_42,Kka2,kka2_1:4,P00552,1.12579,NO,42,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.907,-4.883,1.976,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.168804,0.00679212,1.12579 beta-lactamase_0_F228R,beta-lactamase_0_228,TEM-1,beta-lactamase_0,P62593,1.1258,NO,228,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-2.342,-2.044,-0.298,,0.154,E,B,0.58,-0.42,15.504,15.504,63.29,HHH,-1.53033,0.0500837,0.0046669,1.1258 kka2_1:2_G181K,kka2_1:2_181,Kka2,kka2_1:2,P00552,1.12588,NO,181,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-2.698,-3.658,0.96,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.295029,0.00728319,1.12588 kka2_1:8_S105T,kka2_1:8_105,Kka2,kka2_1:8,P00552,1.12591,NO,105,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.945,-2.444,0.499,,0.056,S,B,0.27,-1.04,2.115,,65.53,PPB,-2.17033,0.100394,0.00847233,1.12591 kka2_1:8_S105T,kka2_1:8_105,Kka2,kka2_1:8,P00552,1.12591,NO,105,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.945,-2.444,0.499,,0.056,S,B,0.27,-1.04,2.115,,65.53,PPB,-2.17033,0.100394,0.00847233,1.12591 kka2_1:8_A9T,kka2_1:8_9,Kka2,kka2_1:8,P00552,1.12594,NO,9,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.079,-3.282,1.203,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.100394,0.00273264,1.12594 kka2_1:8_A9T,kka2_1:8_9,Kka2,kka2_1:8,P00552,1.12594,NO,9,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.079,-3.282,1.203,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.100394,0.00273264,1.12594 kka2_1:8_V46E,kka2_1:8_46,Kka2,kka2_1:8,P00552,1.12599,NO,46,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-2.62,-3.655,1.035,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.100394,0.00631301,1.12599 kka2_1:8_V46E,kka2_1:8_46,Kka2,kka2_1:8,P00552,1.12599,NO,46,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-2.62,-3.655,1.035,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.100394,0.00631301,1.12599 beta-lactamase_0_A77G,beta-lactamase_0_77,TEM-1,beta-lactamase_0,P62593,1.12605,NO,77,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.234,-2.31,1.076,,0.039,H,A,0.46,-0.56,2.591,,64.34,OHH,-1.294,0.0500837,0.00282362,1.12605 kka2_1:8_D156G,kka2_1:8_156,Kka2,kka2_1:8,P00552,1.12607,NO,156,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.696,-3.383,1.687,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.100394,0.00926998,1.12607 kka2_1:8_D156G,kka2_1:8_156,Kka2,kka2_1:8,P00552,1.12607,NO,156,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.696,-3.383,1.687,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.100394,0.00926998,1.12607 kka2_1:1_Q42K,kka2_1:1_42,Kka2,kka2_1:1,P00552,1.12612,NO,42,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.907,-2.899,-0.008,,1.044,T,B,0.4,-0.8,2.792,,71.59,HPO,-2.12433,0.520039,0.00679212,1.12612 beta-lactamase_0_G226C,beta-lactamase_0_226,TEM-1,beta-lactamase_0,P62593,1.12614,NO,226,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.461,-3.342,1.881,,0.701,T,l,0.29,-0.25,23.034,23.034,74.48,HOH,-1.42933,0.0500837,0.00665294,1.12614 kka2_1:8_I246N,kka2_1:8_246,Kka2,kka2_1:8,P00552,1.12614,NO,246,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-2.008,-4.146,2.138,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.100394,0.0139479,1.12614 kka2_1:8_I246N,kka2_1:8_246,Kka2,kka2_1:8,P00552,1.12614,NO,246,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-2.008,-4.146,2.138,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.100394,0.0139479,1.12614 kka2_1:8_D238S,kka2_1:8_238,Kka2,kka2_1:8,P00552,1.12616,NO,238,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.83,-2.933,0.103,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.100394,0.0113863,1.12616 kka2_1:8_D238S,kka2_1:8_238,Kka2,kka2_1:8,P00552,1.12616,NO,238,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.83,-2.933,0.103,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.100394,0.0113863,1.12616 kka2_1:8_V84H,kka2_1:8_84,Kka2,kka2_1:8,P00552,1.1262,NO,84,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-2.279,-3.484,1.205,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.100394,0.00724019,1.1262 kka2_1:8_V84H,kka2_1:8_84,Kka2,kka2_1:8,P00552,1.1262,NO,84,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-2.279,-3.484,1.205,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.100394,0.00724019,1.1262 kka2_1:8_A229M,kka2_1:8_229,Kka2,kka2_1:8,P00552,1.12628,NO,229,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.739,-4.743,3.004,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.100394,0.00942138,1.12628 kka2_1:8_A229M,kka2_1:8_229,Kka2,kka2_1:8,P00552,1.12628,NO,229,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.739,-4.743,3.004,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.100394,0.00942138,1.12628 beta-lactamase_0_S104A,beta-lactamase_0_104,TEM-1,beta-lactamase_0,P62593,1.12632,NO,104,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.015,-2.043,1.028,,0.04,,b,0.27,0.57,1.148,,63.29,HPO,-1.05267,0.0500837,0.00218083,1.12632 kka2_1:4_R253L,kka2_1:4_253,Kka2,kka2_1:4,P00552,1.12632,NO,253,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.356,-3.455,2.099,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.168804,0.0144195,1.12632 kka2_1:4_V198H,kka2_1:4_198,Kka2,kka2_1:4,P00552,1.12635,NO,198,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.719,-4.876,3.157,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.168804,0.00835002,1.12635 beta-lactamase_0_R275N,beta-lactamase_0_275,TEM-1,beta-lactamase_0,P62593,1.12637,NO,275,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.0500837,0.0141984,1.12637 kka2_1:4_Q61C,kka2_1:4_61,Kka2,kka2_1:4,P00552,1.1264,NO,61,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.982,-5.1,2.118,,0.591,H,A,0.64,0.41,3.484,,65.53,HPA,-1.85667,0.168804,0.00612092,1.1264 kka2_1:1_M1I,kka2_1:1_1,Kka2,kka2_1:1,P00552,1.12644,NO,1,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.787,-2.748,0.961,,,,,,,3.101,,62.12,NAHH,-1.787,0.520039,0.00251939,1.12644 kka2_1:2_Q42M,kka2_1:2_42,Kka2,kka2_1:2,P00552,1.12649,NO,42,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.907,-4.883,1.976,,1.044,T,B,0.64,-0.8,2.792,,71.59,HPO,-2.12433,0.295029,0.00679212,1.12649 kka2_1:2_V153F,kka2_1:2_153,Kka2,kka2_1:2,P00552,1.12654,NO,153,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.092,-3.89,2.798,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.295029,0.00501119,1.12654 kka2_1:4_T225L,kka2_1:4_225,Kka2,kka2_1:4,P00552,1.12656,NO,225,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.393,-2.612,0.219,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.168804,0.0113598,1.12656 kka2_1:8_E231R,kka2_1:8_231,Kka2,kka2_1:8,P00552,1.12657,NO,231,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.002,-3.767,1.765,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.100394,0.00732383,1.12657 kka2_1:8_E231R,kka2_1:8_231,Kka2,kka2_1:8,P00552,1.12657,NO,231,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.002,-3.767,1.765,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.100394,0.00732383,1.12657 beta-lactamase_0_K190Y,beta-lactamase_0_190,TEM-1,beta-lactamase_0,P62593,1.1266,NO,190,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-1.994,-4.283,2.289,,0.371,H,A,2.34,0.16,16.606,16.606,77.62,BBH,-1.64167,0.0500837,0.00574527,1.1266 beta-lactamase_0_L49I,beta-lactamase_0_49,TEM-1,beta-lactamase_0,P62593,1.12664,NO,49,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.897,-3.523,1.626,,0.131,T,A,0.55,0.04,13.838,13.838,64.69,AHP,-1.99233,0.0500837,0.00401477,1.12664 beta-lactamase_0_Q86L,beta-lactamase_0_86,TEM-1,beta-lactamase_0,P62593,1.12664,NO,86,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.4,-2.558,0.158,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.0500837,0.00450027,1.12664 kka2_1:4_E230D,kka2_1:4_230,Kka2,kka2_1:4,P00552,1.12664,NO,230,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.672,-2.56,-0.112,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.168804,0.00920051,1.12664 kka2_1:2_L81I,kka2_1:2_81,Kka2,kka2_1:2,P00552,1.12665,NO,81,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.427,-1.722,0.295,,0.46,E,A,1.59,-0.14,1.895,,63.64,HHA,-1.50567,0.295029,0.00805839,1.12665 beta-lactamase_0_I244W,beta-lactamase_0_244,TEM-1,beta-lactamase_0,P62593,1.12668,NO,244,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.555,-5.375,3.82,,,E,B,0.48,-0.84,1.241,,77.62,OHH,-1.385,0.0500837,0.00605379,1.12668 beta-lactamase_0_I258F,beta-lactamase_0_258,TEM-1,beta-lactamase_0,P62593,1.12672,NO,258,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.0500837,0.007931,1.12672 kka2_1:4_D154T,kka2_1:4_154,Kka2,kka2_1:4,P00552,1.12678,NO,154,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-0.876,-3.472,2.596,,0.457,,b,0.29,1.48,15.641,15.641,52.65,HAP,-1.52467,0.168804,0.00292633,1.12678 kka2_1:2_E160N,kka2_1:2_160,Kka2,kka2_1:2,P00552,1.12685,NO,160,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.683,-2.876,1.193,,0.989,G,A,1.04,2.28,3.948,,71.59,AAA,-1.36133,0.295029,0.00935762,1.12685 kka2_1:4_T125N,kka2_1:4_125,Kka2,kka2_1:4,P00552,1.12691,NO,125,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.622,-3.781,1.159,,0.791,T,A,0.82,0.33,1.612,,92.05,BPH,-1.56933,0.168804,0.00821755,1.12691 kka2_1:4_D227C,kka2_1:4_227,Kka2,kka2_1:4,P00552,1.12698,NO,227,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.758,-4.819,3.061,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.168804,0.00745029,1.12698 kka2_1:2_A110M,kka2_1:2_110,Kka2,kka2_1:2,P00552,1.12703,NO,110,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.064,-3.65,1.586,,0.175,H,A,0.46,-1.19,23.237,23.237,71.59,OHA,-1.91867,0.295029,0.00759851,1.12703 kka2_1:8_L158A,kka2_1:8_158,Kka2,kka2_1:8,P00552,1.12705,NO,158,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.947,-3.292,1.345,,0.095,.,B,0.55,0.77,1.607,,63.64,AHA,-1.25333,0.100394,0.00529068,1.12705 kka2_1:8_L158A,kka2_1:8_158,Kka2,kka2_1:8,P00552,1.12705,NO,158,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.947,-3.292,1.345,,0.095,.,B,0.55,0.77,1.607,,63.64,AHA,-1.25333,0.100394,0.00529068,1.12705 kka2_1:4_G74M,kka2_1:4_74,Kka2,kka2_1:4,P00552,1.12714,NO,74,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.18,-4.972,3.792,,0.621,T,l,0.75,0.2,1.032,,64.39,POH,-1.91667,0.168804,0.00587035,1.12714 PSD95pdz3_P311M,PSD95pdz3_311,PSD95pdz3,PSD95pdz3,P31016,1.12715,NO,311,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.236,-4.387,3.151,5.76649,,,,,14.78,,,,OOB,-1.409,0.0758425,0.0030796,1.12715 beta-lactamase_0_R41C,beta-lactamase_0_41,TEM-1,beta-lactamase_0,P62593,1.1272,NO,41,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-0.942,-5.05,4.108,,0.321,E,B,1.2,-0.07,2.68,,65.03,HBH,-1.30267,0.0500837,0.00123327,1.1272 kka2_1:2_G21S,kka2_1:2_21,Kka2,kka2_1:2,P00552,1.12723,NO,21,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.368,-2.431,1.063,,0.586,T,l,0.29,-0.75,2.026,,71.59,HOH,-2.10167,0.295029,0.00709648,1.12723 kka2_1:1_M1L,kka2_1:1_1,Kka2,kka2_1:1,P00552,1.12736,NO,1,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.787,-2.339,0.552,,,,,,,3.101,,62.12,NAHH,-1.787,0.520039,0.00251939,1.12736 kka2_1:8_Q100V,kka2_1:8_100,Kka2,kka2_1:8,P00552,1.12736,NO,100,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.77,-2.771,0.001,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.100394,0.0066405,1.12736 kka2_1:8_Q100V,kka2_1:8_100,Kka2,kka2_1:8,P00552,1.12736,NO,100,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.77,-2.771,0.001,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.100394,0.0066405,1.12736 kka2_1:8_Q219T,kka2_1:8_219,Kka2,kka2_1:8,P00552,1.12746,NO,219,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-0.93,-3.473,2.543,,0.088,H,A,0.4,-0.85,0.897,,50,HPA,-1.05167,0.100394,0.00237913,1.12746 kka2_1:8_Q219T,kka2_1:8_219,Kka2,kka2_1:8,P00552,1.12746,NO,219,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-0.93,-3.473,2.543,,0.088,H,A,0.4,-0.85,0.897,,50,HPA,-1.05167,0.100394,0.00237913,1.12746 kka2_1:4_V84I,kka2_1:4_84,Kka2,kka2_1:4,P00552,1.12748,NO,84,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-2.279,-2.844,0.565,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.168804,0.00724019,1.12748 kka2_1:2_Q26E,kka2_1:2_26,Kka2,kka2_1:2,P00552,1.12756,NO,26,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.18,-2.898,0.718,,0.448,E,B,0.4,0.44,5.022,,92.05,HPP,-2.11167,0.295029,0.00708962,1.12756 kka2_1:4_Q100E,kka2_1:4_100,Kka2,kka2_1:4,P00552,1.1276,NO,100,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.77,-2.743,-0.027,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.168804,0.0066405,1.1276 kka2_1:8_L7W,kka2_1:8_7,Kka2,kka2_1:8,P00552,1.12762,NO,7,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.926,-5.046,3.12,,,,,,,,,71.59,OHB,-2.12333,0.100394,0.00269456,1.12762 kka2_1:8_L7W,kka2_1:8_7,Kka2,kka2_1:8,P00552,1.12762,NO,7,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.926,-5.046,3.12,,,,,,,,,71.59,OHB,-2.12333,0.100394,0.00269456,1.12762 kka2_1:4_E111D,kka2_1:4_111,Kka2,kka2_1:4,P00552,1.12764,NO,111,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.28,-2.742,0.462,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.168804,0.00746789,1.12764 kka2_1:8_Q4D,kka2_1:8_4,Kka2,kka2_1:8,P00552,1.12765,NO,4,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.361,-3.094,0.733,,,,,,,2.026,,71.59,APA,-1.95533,0.100394,0.00239179,1.12765 kka2_1:8_Q4D,kka2_1:8_4,Kka2,kka2_1:8,P00552,1.12765,NO,4,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.361,-3.094,0.733,,,,,,,2.026,,71.59,APA,-1.95533,0.100394,0.00239179,1.12765 beta-lactamase_39_M209C,beta-lactamase_39_209,TEM-1,beta-lactamase_39,P62593,1.12769,NO,209,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.442,-4.758,3.316,,,H,A,0.55,-0.97,1.167,,64.69,HHA,-1.52633,0.0495842,0.00625021,1.12769 beta-lactamase_0_E62R,beta-lactamase_0_62,TEM-1,beta-lactamase_0,P62593,1.12773,NO,62,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.193,-3.663,2.47,,0.342,S,B,1.04,-0.3,5.784,,73.08,AAB,-1.417,0.0500837,0.00264802,1.12773 kka2_1:4_L47A,kka2_1:4_47,Kka2,kka2_1:4,P00552,1.12774,NO,47,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.265,-2.449,1.184,,0.139,E,B,0.55,-0.86,2.369,,63.26,HHH,-1.77933,0.168804,0.00509386,1.12774 kka2_1:1_A79Q,kka2_1:1_79,Kka2,kka2_1:1,P00552,1.12779,NO,79,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.368,-2.757,0.389,,0.563,.,B,0.46,-0.43,7.792,7.792,71.59,HHH,-1.752,0.520039,0.00664821,1.12779 beta-lactamase_0_S57A,beta-lactamase_0_57,TEM-1,beta-lactamase_0,P62593,1.1278,NO,57,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.918,-1.894,-0.024,,0.352,E,B,0.27,-0.18,1.454,,72.73,APH,-2.29167,0.0500837,0.00492804,1.1278 PSD95pdz3_E334V,PSD95pdz3_334,PSD95pdz3,PSD95pdz3,P31016,1.12782,NO,334,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.404,-3.21,1.806,5.60175,,,,,53.09,,,,OAO,-1.14,0.0758425,0.000912998,1.12782 kka2_1:2_V16I,kka2_1:2_16,Kka2,kka2_1:2,P00552,1.12791,NO,16,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-3.087,-3.948,0.861,,0.742,T,A,0.44,0.34,1.746,,71.59,HHA,-2.211,0.295029,0.00694011,1.12791 beta-lactamase_0_G240K,beta-lactamase_0_240,TEM-1,beta-lactamase_0,P62593,1.12799,NO,240,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.0500837,0.00591201,1.12799 kka2_1:2_A71R,kka2_1:2_71,Kka2,kka2_1:2,P00552,1.12806,NO,71,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.824,-2.453,0.629,,0.553,H,A,0.46,0.08,9.788,,64.39,HHP,-1.74033,0.295029,0.00727707,1.12806 kka2_1:8_G74S,kka2_1:8_74,Kka2,kka2_1:8,P00552,1.12806,NO,74,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.18,-2.717,1.537,,0.621,T,l,0.29,0.2,2.014,,64.39,POH,-1.91667,0.100394,0.00587035,1.12806 kka2_1:8_G74S,kka2_1:8_74,Kka2,kka2_1:8,P00552,1.12806,NO,74,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.18,-2.717,1.537,,0.621,T,l,0.29,0.2,2.014,,64.39,POH,-1.91667,0.100394,0.00587035,1.12806 kka2_1:8_I254E,kka2_1:8_254,Kka2,kka2_1:8,P00552,1.12806,NO,254,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.933,-3.931,1.998,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.100394,0.0132375,1.12806 kka2_1:8_I254E,kka2_1:8_254,Kka2,kka2_1:8,P00552,1.12806,NO,254,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.933,-3.931,1.998,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.100394,0.0132375,1.12806 kka2_1:4_E230G,kka2_1:4_230,Kka2,kka2_1:4,P00552,1.1281,NO,230,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.672,-3.574,0.902,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.168804,0.00920051,1.1281 kka2_1:4_R122H,kka2_1:4_122,Kka2,kka2_1:4,P00552,1.12811,NO,122,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.175,-3.287,1.112,,0.487,H,A,0.16,0.26,16.436,16.436,71.59,BBH,-1.53833,0.168804,0.00736512,1.12811 kka2_1:8_P12S,kka2_1:8_12,Kka2,kka2_1:8,P00552,1.12825,NO,12,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.853,-3.336,2.483,,,.,B,0.52,1.25,2.41,,48.11,POH,-1.80767,0.100394,0.00500011,1.12825 kka2_1:8_P12S,kka2_1:8_12,Kka2,kka2_1:8,P00552,1.12825,NO,12,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-0.853,-3.336,2.483,,,.,B,0.52,1.25,2.41,,48.11,POH,-1.80767,0.100394,0.00500011,1.12825 kka2_1:8_Q155A,kka2_1:8_155,Kka2,kka2_1:8,P00552,1.12827,NO,155,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.606,-2.225,-0.381,,0.525,T,A,0.64,1.49,,,63.64,APA,-1.726,0.100394,0.00641853,1.12827 kka2_1:8_Q155A,kka2_1:8_155,Kka2,kka2_1:8,P00552,1.12827,NO,155,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.606,-2.225,-0.381,,0.525,T,A,0.64,1.49,,,63.64,APA,-1.726,0.100394,0.00641853,1.12827 beta-lactamase_0_Q203G,beta-lactamase_0_203,TEM-1,beta-lactamase_0,P62593,1.12831,NO,203,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.168,-2.805,0.637,,0.47,H,A,0.64,-0.38,14.541,14.541,65.38,BPP,-1.614,0.0500837,0.00631514,1.12831 kka2_1:2_A176S,kka2_1:2_176,Kka2,kka2_1:2,P00552,1.12831,NO,176,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.621,-1.88,0.259,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.295029,0.0083587,1.12831 kka2_1:2_A65V,kka2_1:2_65,Kka2,kka2_1:2,P00552,1.12832,NO,65,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.744,-2.657,0.913,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.295029,0.00709258,1.12832 kka2_1:8_D52C,kka2_1:8_52,Kka2,kka2_1:8,P00552,1.12844,NO,52,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.271,-5.339,3.068,,0.22,E,B,0.75,0.8,5.447,,71.59,PAH,-2.38367,0.100394,0.00175694,1.12844 kka2_1:8_D52C,kka2_1:8_52,Kka2,kka2_1:8,P00552,1.12844,NO,52,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.271,-5.339,3.068,,0.22,E,B,0.75,0.8,5.447,,71.59,PAH,-2.38367,0.100394,0.00175694,1.12844 beta-lactamase_0_R118L,beta-lactamase_0_118,TEM-1,beta-lactamase_0,P62593,1.12846,NO,118,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.413,-2.872,0.459,,0.457,H,A,1.2,1.39,3.961,,77.62,HBA,-1.785,0.0500837,0.00538794,1.12846 kka2_1:4_H139Y,kka2_1:4_139,Kka2,kka2_1:4,P00552,1.1285,NO,139,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-2.809,-3.482,0.673,,0.471,H,A,0.17,0.68,12.761,12.761,63.64,BBB,-2.22,0.168804,0.00734779,1.1285 kka2_1:4_L7P,kka2_1:4_7,Kka2,kka2_1:4,P00552,1.12852,NO,7,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.926,-3.817,1.891,,,,,,,3.012,,71.59,OHB,-2.12333,0.168804,0.00269456,1.12852 kka2_1:8_Y218C,kka2_1:8_218,Kka2,kka2_1:8,P00552,1.12852,NO,218,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-1.438,-2.974,1.536,,0.122,H,A,1.25,-0.69,2.923,,56.06,BHP,-1.17533,0.100394,0.0126098,1.12852 kka2_1:8_Y218C,kka2_1:8_218,Kka2,kka2_1:8,P00552,1.12852,NO,218,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-1.438,-2.974,1.536,,0.122,H,A,1.25,-0.69,2.923,,56.06,BHP,-1.17533,0.100394,0.0126098,1.12852 beta-lactamase_0_A77D,beta-lactamase_0_77,TEM-1,beta-lactamase_0,P62593,1.12859,NO,77,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.234,-3.775,2.541,,0.039,H,A,0.46,-0.56,2.591,,64.34,OHH,-1.294,0.0500837,0.00282362,1.12859 kka2_1:8_D5E,kka2_1:8_5,Kka2,kka2_1:8,P00552,1.1286,NO,5,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.306,-1.813,0.507,,,,,,,1.147,,71.59,PAO,-1.784,0.100394,0.00222864,1.1286 kka2_1:8_D5E,kka2_1:8_5,Kka2,kka2_1:8,P00552,1.1286,NO,5,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.306,-1.813,0.507,,,,,,,1.147,,71.59,PAO,-1.784,0.100394,0.00222864,1.1286 beta-lactamase_0_E46M,beta-lactamase_0_46,TEM-1,beta-lactamase_0,P62593,1.12864,NO,46,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.94,-4.375,2.435,,0.021,E,B,1.04,0.14,30.306,30.306,59.44,HAH,-2.079,0.0500837,0.00427568,1.12864 kka2_1:4_A229M,kka2_1:4_229,Kka2,kka2_1:4,P00552,1.12865,NO,229,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.739,-4.743,3.004,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.168804,0.00942138,1.12865 beta-lactamase_0_S122Y,beta-lactamase_0_122,TEM-1,beta-lactamase_0,P62593,1.12869,NO,122,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.406,-4.156,1.75,,0.352,H,A,0.27,-0.54,30.794,30.794,77.62,OPH,-1.39767,0.0500837,0.00497825,1.12869 beta-lactamase_39_D212W,beta-lactamase_39_212,TEM-1,beta-lactamase_39,P62593,1.12875,NO,212,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.624,-5.54,3.916,,0.037,,b,0.75,-0.58,10.748,10.748,74.48,HAB,-1.77667,0.0495842,0.00644302,1.12875 kka2_1:4_A25E,kka2_1:4_25,Kka2,kka2_1:4,P00552,1.12876,NO,25,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.496,-1.817,-0.679,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.168804,0.00595636,1.12876 kka2_1:4_E235L,kka2_1:4_235,Kka2,kka2_1:4,P00552,1.12876,NO,235,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.955,-3.621,1.666,,0.631,H,A,1.04,0.12,23.175,23.175,65.53,OAH,-2.07267,0.168804,0.0102806,1.12876 kka2_1:4_Q61H,kka2_1:4_61,Kka2,kka2_1:4,P00552,1.12888,NO,61,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.982,-4.796,1.814,,0.591,H,A,0.64,0.41,3.484,,65.53,HPA,-1.85667,0.168804,0.00612092,1.12888 kka2_1:8_K138V,kka2_1:8_138,Kka2,kka2_1:8,P00552,1.12893,NO,138,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-2.5,-3.083,0.583,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.100394,0.00628542,1.12893 kka2_1:8_K138V,kka2_1:8_138,Kka2,kka2_1:8,P00552,1.12893,NO,138,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-2.5,-3.083,0.583,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.100394,0.00628542,1.12893 kka2_1:8_T225A,kka2_1:8_225,Kka2,kka2_1:8,P00552,1.12897,NO,225,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.393,-1.787,-0.606,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.100394,0.0113598,1.12897 kka2_1:8_T225A,kka2_1:8_225,Kka2,kka2_1:8,P00552,1.12897,NO,225,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.393,-1.787,-0.606,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.100394,0.0113598,1.12897 beta-lactamase_0_W163S,beta-lactamase_0_163,TEM-1,beta-lactamase_0,P62593,1.12898,NO,163,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-1.843,-3.614,1.771,,0.467,,B,0.47,-0.5,13.843,13.843,63.99,BHA,-1.269,0.0500837,0.00418955,1.12898 kka2_1:8_L53E,kka2_1:8_53,Kka2,kka2_1:8,P00552,1.12899,NO,53,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-2.681,-2.451,-0.23,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.100394,0.00671168,1.12899 kka2_1:8_L53E,kka2_1:8_53,Kka2,kka2_1:8,P00552,1.12899,NO,53,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-2.681,-2.451,-0.23,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.100394,0.00671168,1.12899 kka2_1:2_Q61K,kka2_1:2_61,Kka2,kka2_1:2,P00552,1.12906,NO,61,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.982,-3.601,0.619,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.295029,0.00612092,1.12906 beta-lactamase_0_I140R,beta-lactamase_0_140,TEM-1,beta-lactamase_0,P62593,1.1291,NO,140,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.733,-4.193,2.46,,0.128,H,A,0.48,0.41,4.714,,73.08,PHO,-1.48733,0.0500837,0.00597777,1.1291 kka2_1:4_G10H,kka2_1:4_10,Kka2,kka2_1:4,P00552,1.12913,NO,10,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.921,-4.434,2.513,,,,,,,1.862,,71.59,HOP,-2.10733,0.168804,0.00289233,1.12913 kka2_1:8_T130C,kka2_1:8_130,Kka2,kka2_1:8,P00552,1.12913,NO,130,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.392,-3.62,1.228,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.100394,0.00804204,1.12913 kka2_1:8_T130C,kka2_1:8_130,Kka2,kka2_1:8,P00552,1.12913,NO,130,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.392,-3.62,1.228,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.100394,0.00804204,1.12913 kka2_1:8_D23H,kka2_1:8_23,Kka2,kka2_1:8,P00552,1.12914,NO,23,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.459,-3.07,0.611,,0.695,E,B,0.75,-0.65,,,65.53,HAH,-1.94033,0.100394,0.007195,1.12914 kka2_1:8_D23H,kka2_1:8_23,Kka2,kka2_1:8,P00552,1.12914,NO,23,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.459,-3.07,0.611,,0.695,E,B,0.75,-0.65,,,65.53,HAH,-1.94033,0.100394,0.007195,1.12914 kka2_1:2_A25N,kka2_1:2_25,Kka2,kka2_1:2,P00552,1.12916,NO,25,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.496,-3.071,0.575,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.295029,0.00595636,1.12916 kka2_1:2_A9I,kka2_1:2_9,Kka2,kka2_1:2,P00552,1.12918,NO,9,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.079,-2.507,0.428,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.295029,0.00273264,1.12918 kka2_1:8_E235R,kka2_1:8_235,Kka2,kka2_1:8,P00552,1.12919,NO,235,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.955,-2.75,0.795,,0.631,H,A,1.52,0.12,,,65.53,OAH,-2.07267,0.100394,0.0102806,1.12919 kka2_1:8_E235R,kka2_1:8_235,Kka2,kka2_1:8,P00552,1.12919,NO,235,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.955,-2.75,0.795,,0.631,H,A,1.52,0.12,,,65.53,OAH,-2.07267,0.100394,0.0102806,1.12919 kka2_1:2_A110Y,kka2_1:2_110,Kka2,kka2_1:2,P00552,1.1293,NO,110,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.064,-4.356,2.292,,0.175,H,A,0.46,-1.19,23.237,23.237,71.59,OHA,-1.91867,0.295029,0.00759851,1.1293 WW_domain_V171L,WW_domain_171,Yap65,WW_domain,P46937,1.12933,NO,171,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.547,-2,0.453,,,,,,,3.459,,70.24,AHO,-1.265,0.153962,0.00184125,1.12933 kka2_1:4_L94M,kka2_1:4_94,Kka2,kka2_1:4,P00552,1.12938,NO,94,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.618,-1.512,-0.106,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.168804,0.00520888,1.12938 kka2_1:8_Q27L,kka2_1:8_27,Kka2,kka2_1:8,P00552,1.1294,NO,27,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-1.659,-2.589,0.93,,0.608,.,A,0.64,0.71,3.919,,65.53,PPP,-1.90733,0.100394,0.00595365,1.1294 kka2_1:8_Q27L,kka2_1:8_27,Kka2,kka2_1:8,P00552,1.1294,NO,27,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-1.659,-2.589,0.93,,0.608,.,A,0.64,0.71,3.919,,65.53,PPP,-1.90733,0.100394,0.00595365,1.1294 kka2_1:4_T72A,kka2_1:4_72,Kka2,kka2_1:4,P00552,1.12942,NO,72,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.38,-2.118,-0.262,,0.784,H,A,0.82,0.29,6.463,,65.53,HPP,-2.238,0.168804,0.00750756,1.12942 beta-lactamase_0_I45F,beta-lactamase_0_45,TEM-1,beta-lactamase_0,P62593,1.12949,NO,45,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-2.421,-3.147,0.726,,,E,B,0.48,-0.3,1.375,,77.62,HHA,-2.30267,0.0500837,0.00452842,1.12949 kka2_1:4_I196V,kka2_1:4_196,Kka2,kka2_1:4,P00552,1.12951,NO,196,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-2.115,-2.455,0.34,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.168804,0.0107273,1.12951 kka2_1:4_E199V,kka2_1:4_199,Kka2,kka2_1:4,P00552,1.12965,NO,199,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.234,-2.91,0.676,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.168804,0.00854122,1.12965 kka2_1:4_A9F,kka2_1:4_9,Kka2,kka2_1:4,P00552,1.12969,NO,9,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.079,-3.934,1.855,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.168804,0.00273264,1.12969 WW_domain_D170G,WW_domain_170,Yap65,WW_domain,P46937,1.12974,NO,170,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.213,-3.033,1.82,,,,,,,0.399,,15.87,OAH,-1.38,0.153962,0.00123319,1.12974 beta-lactamase_0_G240M,beta-lactamase_0_240,TEM-1,beta-lactamase_0,P62593,1.12995,NO,240,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.0500837,0.00591201,1.12995 kka2_1:2_D180C,kka2_1:2_180,Kka2,kka2_1:2,P00552,1.12996,NO,180,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.416,-5.213,2.797,,1.03,S,a,0.75,1.5,1.27,,71.59,OAO,-2.02933,0.295029,0.00756412,1.12996 beta-lactamase_0_D155E,beta-lactamase_0_155,TEM-1,beta-lactamase_0,P62593,1.12997,NO,155,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-0.889,-2.299,1.41,,0.049,,B,0.75,-0.9,16.833,16.833,64.69,OAB,-1.62267,0.0500837,0.00135315,1.12997 beta-lactamase_0_D113T,beta-lactamase_0_113,TEM-1,beta-lactamase_0,P62593,1.13017,NO,113,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.829,-2.544,0.715,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.0500837,0.00474112,1.13017 kka2_1:2_E149Y,kka2_1:2_149,Kka2,kka2_1:2,P00552,1.13018,NO,149,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.994,-4.359,2.365,,0.674,H,A,1.04,1.63,15.361,15.361,71.59,HAH,-1.59667,0.295029,0.00803343,1.13018 kka2_1:8_E96V,kka2_1:8_96,Kka2,kka2_1:8,P00552,1.13018,NO,96,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.573,-2.716,0.143,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.100394,0.00369441,1.13018 kka2_1:8_E96V,kka2_1:8_96,Kka2,kka2_1:8,P00552,1.13018,NO,96,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.573,-2.716,0.143,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.100394,0.00369441,1.13018 beta-lactamase_0_T147R,beta-lactamase_0_147,TEM-1,beta-lactamase_0,P62593,1.13025,NO,147,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.149,-3.809,2.66,,0.281,H,A,0.22,-0.68,3.487,,64.34,HPH,-1.456,0.0500837,0.00226017,1.13025 kka2_1:4_S114T,kka2_1:4_114,Kka2,kka2_1:4,P00552,1.13036,NO,114,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.527,-2.564,0.037,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.168804,0.00705262,1.13036 kka2_1:8_S114H,kka2_1:8_114,Kka2,kka2_1:8,P00552,1.13037,NO,114,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.527,-3.031,0.504,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.100394,0.00705262,1.13037 kka2_1:8_S114H,kka2_1:8_114,Kka2,kka2_1:8,P00552,1.13037,NO,114,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.527,-3.031,0.504,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.100394,0.00705262,1.13037 kka2_1:8_A71T,kka2_1:8_71,Kka2,kka2_1:8,P00552,1.13043,NO,71,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.824,-2.666,0.842,,0.553,H,A,0.46,0.08,18.64,18.64,64.39,HHP,-1.74033,0.100394,0.00727707,1.13043 kka2_1:8_A71T,kka2_1:8_71,Kka2,kka2_1:8,P00552,1.13043,NO,71,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.824,-2.666,0.842,,0.553,H,A,0.46,0.08,18.64,18.64,64.39,HHP,-1.74033,0.100394,0.00727707,1.13043 beta-lactamase_0_D155H,beta-lactamase_0_155,TEM-1,beta-lactamase_0,P62593,1.13047,NO,155,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.889,-4.424,3.535,,0.049,,B,0.75,-0.9,16.833,16.833,64.69,OAB,-1.62267,0.0500837,0.00135315,1.13047 beta-lactamase_0_V106G,beta-lactamase_0_106,TEM-1,beta-lactamase_0,P62593,1.13054,NO,106,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.218,-3.752,2.534,,0.258,T,A,0.44,0.24,0.952,,72.73,OHP,-1.04933,0.0500837,0.00304168,1.13054 kka2_1:8_E142Q,kka2_1:8_142,Kka2,kka2_1:8,P00552,1.13059,NO,142,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.221,-3.009,0.788,,0.471,H,A,1.04,0.85,2.655,,65.53,HAB,-2.08033,0.100394,0.00748883,1.13059 kka2_1:8_E142Q,kka2_1:8_142,Kka2,kka2_1:8,P00552,1.13059,NO,142,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.221,-3.009,0.788,,0.471,H,A,1.04,0.85,2.655,,65.53,HAB,-2.08033,0.100394,0.00748883,1.13059 beta-lactamase_0_A132L,beta-lactamase_0_132,TEM-1,beta-lactamase_0,P62593,1.1306,NO,132,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.9,-3.146,2.246,,,H,A,0.46,-0.93,2.249,,64.69,PHH,-1.138,0.0500837,0.000962524,1.1306 kka2_1:2_R202Q,kka2_1:2_202,Kka2,kka2_1:2,P00552,1.13067,NO,202,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.761,-2.622,0.861,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.295029,0.00696498,1.13067 kka2_1:8_T28Y,kka2_1:8_28,Kka2,kka2_1:8,P00552,1.1307,NO,28,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.883,-4.4,2.517,,0.353,S,B,0.22,2.02,18.114,18.114,63.64,PPH,-1.74467,0.100394,0.00743084,1.1307 kka2_1:8_T28Y,kka2_1:8_28,Kka2,kka2_1:8,P00552,1.1307,NO,28,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.883,-4.4,2.517,,0.353,S,B,0.22,2.02,18.114,18.114,63.64,PPH,-1.74467,0.100394,0.00743084,1.1307 beta-lactamase_0_G154N,beta-lactamase_0_154,TEM-1,beta-lactamase_0,P62593,1.13074,NO,154,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.823,-3.507,2.684,,0.54,T,l,0.29,-0.56,3.629,,64.69,HOA,-1.635,0.0500837,0.00180205,1.13074 beta-lactamase_39_E195M,beta-lactamase_39_195,TEM-1,beta-lactamase_39,P62593,1.13076,NO,195,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.186,-4.856,2.67,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.0495842,0.00496565,1.13076 kka2_1:2_T73C,kka2_1:2_73,Kka2,kka2_1:2,P00552,1.13085,NO,73,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.51,-3.584,1.074,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.295029,0.00628605,1.13085 kka2_1:8_D250I,kka2_1:8_250,Kka2,kka2_1:8,P00552,1.13088,NO,250,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.015,-4.121,3.106,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.100394,0.0177103,1.13088 kka2_1:8_D250I,kka2_1:8_250,Kka2,kka2_1:8,P00552,1.13088,NO,250,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.015,-4.121,3.106,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.100394,0.0177103,1.13088 kka2_1:4_I29L,kka2_1:4_29,Kka2,kka2_1:4,P00552,1.13089,NO,29,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.692,-1.88,0.188,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.168804,0.00619521,1.13089 kka2_1:8_K138M,kka2_1:8_138,Kka2,kka2_1:8,P00552,1.13093,NO,138,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-2.5,-4.844,2.344,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.100394,0.00628542,1.13093 kka2_1:8_K138M,kka2_1:8_138,Kka2,kka2_1:8,P00552,1.13093,NO,138,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-2.5,-4.844,2.344,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.100394,0.00628542,1.13093 kka2_1:8_Q26H,kka2_1:8_26,Kka2,kka2_1:8,P00552,1.13106,NO,26,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.18,-3.435,1.255,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.100394,0.00708962,1.13106 kka2_1:8_Q26H,kka2_1:8_26,Kka2,kka2_1:8,P00552,1.13106,NO,26,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.18,-3.435,1.255,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.100394,0.00708962,1.13106 beta-lactamase_0_E238G,beta-lactamase_0_238,TEM-1,beta-lactamase_0,P62593,1.13107,NO,238,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.0500837,0.00743256,1.13107 kka2_1:4_G95H,kka2_1:4_95,Kka2,kka2_1:4,P00552,1.13109,NO,95,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-2.403,-4.673,2.27,,0.126,E,B,0.29,-0.74,0.359,,71.59,HOA,-2.198,0.168804,0.00743616,1.13109 kka2_1:8_P249A,kka2_1:8_249,Kka2,kka2_1:8,P00552,1.1311,NO,249,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.867,-2.101,0.234,,0.406,.,B,0.52,-0.01,1.699,,92.05,HOA,-1.66867,0.100394,0.011045,1.1311 kka2_1:8_P249A,kka2_1:8_249,Kka2,kka2_1:8,P00552,1.1311,NO,249,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.867,-2.101,0.234,,0.406,.,B,0.52,-0.01,1.699,,92.05,HOA,-1.66867,0.100394,0.011045,1.1311 kka2_1:8_G74R,kka2_1:8_74,Kka2,kka2_1:8,P00552,1.13112,NO,74,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.18,-3.943,2.763,,0.621,T,l,0.29,0.2,2.014,,64.39,POH,-1.91667,0.100394,0.00587035,1.13112 kka2_1:8_G74R,kka2_1:8_74,Kka2,kka2_1:8,P00552,1.13112,NO,74,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.18,-3.943,2.763,,0.621,T,l,0.29,0.2,2.014,,64.39,POH,-1.91667,0.100394,0.00587035,1.13112 kka2_1:8_R147V,kka2_1:8_147,Kka2,kka2_1:8,P00552,1.13115,NO,147,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.123,-3.865,2.742,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.100394,0.00549168,1.13115 kka2_1:8_R147V,kka2_1:8_147,Kka2,kka2_1:8,P00552,1.13115,NO,147,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.123,-3.865,2.742,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.100394,0.00549168,1.13115 kka2_1:2_T130M,kka2_1:2_130,Kka2,kka2_1:2,P00552,1.13117,NO,130,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.392,-3.607,1.215,,0.561,G,A,0.22,0.77,0.5,,92.05,HPO,-1.62633,0.295029,0.00804204,1.13117 kka2_1:8_V84A,kka2_1:8_84,Kka2,kka2_1:8,P00552,1.13119,NO,84,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-2.279,-1.994,-0.285,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.100394,0.00724019,1.13119 kka2_1:8_V84A,kka2_1:8_84,Kka2,kka2_1:8,P00552,1.13119,NO,84,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-2.279,-1.994,-0.285,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.100394,0.00724019,1.13119 beta-lactamase_0_L49H,beta-lactamase_0_49,TEM-1,beta-lactamase_0,P62593,1.13125,NO,49,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.897,-4.794,2.897,,0.131,T,A,0.55,0.04,13.838,13.838,64.69,AHP,-1.99233,0.0500837,0.00401477,1.13125 kka2_1:8_R44G,kka2_1:8_44,Kka2,kka2_1:8,P00552,1.13125,NO,44,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.062,-2.106,0.044,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.100394,0.00745043,1.13125 kka2_1:8_R44G,kka2_1:8_44,Kka2,kka2_1:8,P00552,1.13125,NO,44,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.062,-2.106,0.044,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.100394,0.00745043,1.13125 kka2_1:8_R143T,kka2_1:8_143,Kka2,kka2_1:8,P00552,1.13128,NO,143,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.525,-2.557,0.032,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.100394,0.00662247,1.13128 kka2_1:8_R143T,kka2_1:8_143,Kka2,kka2_1:8,P00552,1.13128,NO,143,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.525,-2.557,0.032,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.100394,0.00662247,1.13128 kka2_1:8_K175P,kka2_1:8_175,Kka2,kka2_1:8,P00552,1.13145,NO,175,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-2.897,-4.168,1.271,,0.579,H,A,2.34,0.51,15.316,15.316,71.59,HBH,-1.82333,0.100394,0.00693093,1.13145 kka2_1:8_K175P,kka2_1:8_175,Kka2,kka2_1:8,P00552,1.13145,NO,175,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-2.897,-4.168,1.271,,0.579,H,A,2.34,0.51,15.316,15.316,71.59,HBH,-1.82333,0.100394,0.00693093,1.13145 kka2_1:8_P12H,kka2_1:8_12,Kka2,kka2_1:8,P00552,1.1315,NO,12,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.853,-4.718,3.865,,,.,B,0.52,1.25,2.41,,48.11,POH,-1.80767,0.100394,0.00500011,1.1315 kka2_1:8_P12H,kka2_1:8_12,Kka2,kka2_1:8,P00552,1.1315,NO,12,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.853,-4.718,3.865,,,.,B,0.52,1.25,2.41,,48.11,POH,-1.80767,0.100394,0.00500011,1.1315 PSD95pdz3_G344R,PSD95pdz3_344,PSD95pdz3,PSD95pdz3,P31016,1.13151,NO,344,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.008,-3.615,2.607,4.83855,,,,,14.06,,,,HOO,-1.10767,0.0758425,0.00078498,1.13151 kka2_1:8_R143A,kka2_1:8_143,Kka2,kka2_1:8,P00552,1.13159,NO,143,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.525,-2.1,-0.425,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.100394,0.00662247,1.13159 kka2_1:8_R143A,kka2_1:8_143,Kka2,kka2_1:8,P00552,1.13159,NO,143,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.525,-2.1,-0.425,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.100394,0.00662247,1.13159 beta-lactamase_0_T138W,beta-lactamase_0_138,TEM-1,beta-lactamase_0,P62593,1.13161,NO,138,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.506,-5.551,3.045,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.0500837,0.00487868,1.13161 kka2_1:8_I115L,kka2_1:8_115,Kka2,kka2_1:8,P00552,1.13161,NO,115,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.606,-1.667,0.061,,0.105,H,A,1.52,-1.18,4.064,,65.53,PHH,-2.205,0.100394,0.00836567,1.13161 kka2_1:8_I115L,kka2_1:8_115,Kka2,kka2_1:8,P00552,1.13161,NO,115,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.606,-1.667,0.061,,0.105,H,A,1.52,-1.18,4.064,,65.53,PHH,-2.205,0.100394,0.00836567,1.13161 kka2_1:8_E3Q,kka2_1:8_3,Kka2,kka2_1:8,P00552,1.13172,NO,3,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.199,-3.602,1.403,,,,,,,7.22,,92.05,HAP,-2.11567,0.100394,0.00267607,1.13172 kka2_1:8_E3Q,kka2_1:8_3,Kka2,kka2_1:8,P00552,1.13172,NO,3,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.199,-3.602,1.403,,,,,,,7.22,,92.05,HAP,-2.11567,0.100394,0.00267607,1.13172 kka2_1:4_Q252G,kka2_1:4_252,Kka2,kka2_1:4,P00552,1.13178,NO,252,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.63,-2.545,-0.085,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.168804,0.0121001,1.13178 beta-lactamase_0_I244D,beta-lactamase_0_244,TEM-1,beta-lactamase_0,P62593,1.1318,NO,244,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.555,-3.943,2.388,,,E,B,0.48,-0.84,1.241,,77.62,OHH,-1.385,0.0500837,0.00605379,1.1318 kka2_1:2_H139Q,kka2_1:2_139,Kka2,kka2_1:2,P00552,1.13181,NO,139,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-2.809,-2.861,0.052,,0.471,H,A,0.87,0.68,13.912,13.912,63.64,BBB,-2.22,0.295029,0.00734779,1.13181 kka2_1:8_Q155Y,kka2_1:8_155,Kka2,kka2_1:8,P00552,1.13182,NO,155,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.606,-4.298,1.692,,0.525,T,A,0.64,1.49,,,63.64,APA,-1.726,0.100394,0.00641853,1.13182 kka2_1:8_Q155Y,kka2_1:8_155,Kka2,kka2_1:8,P00552,1.13182,NO,155,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.606,-4.298,1.692,,0.525,T,A,0.64,1.49,,,63.64,APA,-1.726,0.100394,0.00641853,1.13182 kka2_1:8_A9R,kka2_1:8_9,Kka2,kka2_1:8,P00552,1.1319,NO,9,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.079,-3.835,1.756,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.100394,0.00273264,1.1319 kka2_1:8_A9R,kka2_1:8_9,Kka2,kka2_1:8,P00552,1.1319,NO,9,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.079,-3.835,1.756,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.100394,0.00273264,1.1319 gb1_V255K,gb1_255,gb1,gb1,P06654,1.13191,NO,255,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-3.127,-3.288,0.161,,,,,,,1.323,,45.54,BHH,-2.03867,0.177985,0.00408354,1.13191 kka2_1:4_A64K,kka2_1:4_64,Kka2,kka2_1:4,P00552,1.13195,NO,64,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.496,-3.777,2.281,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.168804,0.00705578,1.13195 kka2_1:8_L60V,kka2_1:8_60,Kka2,kka2_1:8,P00552,1.13197,NO,60,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.997,-2.277,1.28,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.100394,0.00262176,1.13197 kka2_1:8_L60V,kka2_1:8_60,Kka2,kka2_1:8,P00552,1.13197,NO,60,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-0.997,-2.277,1.28,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.100394,0.00262176,1.13197 beta-lactamase_0_A84I,beta-lactamase_0_84,TEM-1,beta-lactamase_0,P62593,1.13203,NO,84,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.651,-3.932,2.281,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.0500837,0.00503822,1.13203 kka2_1:2_Q163K,kka2_1:2_163,Kka2,kka2_1:2,P00552,1.13207,NO,163,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.162,-2.924,0.762,,0.58,T,B,0.64,1.85,3.888,,64.02,BPO,-1.78333,0.295029,0.00719507,1.13207 kka2_1:8_Q61S,kka2_1:8_61,Kka2,kka2_1:8,P00552,1.13217,NO,61,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.982,-2.728,-0.254,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.100394,0.00612092,1.13217 kka2_1:8_Q61S,kka2_1:8_61,Kka2,kka2_1:8,P00552,1.13217,NO,61,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.982,-2.728,-0.254,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.100394,0.00612092,1.13217 beta-lactamase_0_A77C,beta-lactamase_0_77,TEM-1,beta-lactamase_0,P62593,1.13224,NO,77,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.234,-4.708,3.474,,0.039,H,A,0.46,-0.56,2.591,,64.34,OHH,-1.294,0.0500837,0.00282362,1.13224 kka2_1:2_S114H,kka2_1:2_114,Kka2,kka2_1:2,P00552,1.13226,NO,114,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.527,-3.031,0.504,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.295029,0.00705262,1.13226 beta-lactamase_0_S241C,beta-lactamase_0_241,TEM-1,beta-lactamase_0,P62593,1.1323,NO,241,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.0500837,0.00452736,1.1323 kka2_1:8_A9C,kka2_1:8_9,Kka2,kka2_1:8,P00552,1.13231,NO,9,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.079,-4.697,2.618,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.100394,0.00273264,1.13231 kka2_1:8_A9C,kka2_1:8_9,Kka2,kka2_1:8,P00552,1.13231,NO,9,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.079,-4.697,2.618,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.100394,0.00273264,1.13231 PSD95pdz3_E334W,PSD95pdz3_334,PSD95pdz3,PSD95pdz3,P31016,1.13231,NO,334,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.404,-5.004,3.6,5.60175,,,,,53.09,,,,OAO,-1.14,0.0758425,0.000912998,1.13231 kka2_1:4_Q219A,kka2_1:4_219,Kka2,kka2_1:4,P00552,1.13241,NO,219,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-0.93,-3.129,2.199,,0.088,H,A,0.64,-0.85,1.537,,50,HPA,-1.05167,0.168804,0.00237913,1.13241 kka2_1:8_A255C,kka2_1:8_255,Kka2,kka2_1:8,P00552,1.13242,NO,255,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.715,-5.069,3.354,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.100394,0.0126809,1.13242 kka2_1:8_A255C,kka2_1:8_255,Kka2,kka2_1:8,P00552,1.13242,NO,255,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.715,-5.069,3.354,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.100394,0.0126809,1.13242 kka2_1:8_Q4E,kka2_1:8_4,Kka2,kka2_1:8,P00552,1.13242,NO,4,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.361,-3.058,0.697,,,,,,,2.026,,71.59,APA,-1.95533,0.100394,0.00239179,1.13242 kka2_1:8_Q4E,kka2_1:8_4,Kka2,kka2_1:8,P00552,1.13242,NO,4,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.361,-3.058,0.697,,,,,,,2.026,,71.59,APA,-1.95533,0.100394,0.00239179,1.13242 beta-lactamase_0_R275Y,beta-lactamase_0_275,TEM-1,beta-lactamase_0,P62593,1.13246,NO,275,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.0500837,0.0141984,1.13246 kka2_1:8_G6A,kka2_1:8_6,Kka2,kka2_1:8,P00552,1.13248,NO,6,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.685,-2.835,1.15,,,,,,,,,71.59,AOH,-1.639,0.100394,0.00204693,1.13248 kka2_1:8_G6A,kka2_1:8_6,Kka2,kka2_1:8,P00552,1.13248,NO,6,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.685,-2.835,1.15,,,,,,,,,71.59,AOH,-1.639,0.100394,0.00204693,1.13248 kka2_1:8_I29N,kka2_1:8_29,Kka2,kka2_1:8,P00552,1.13248,NO,29,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.692,-3.146,1.454,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.100394,0.00619521,1.13248 kka2_1:8_I29N,kka2_1:8_29,Kka2,kka2_1:8,P00552,1.13248,NO,29,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.692,-3.146,1.454,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.100394,0.00619521,1.13248 beta-lactamase_0_D36C,beta-lactamase_0_36,TEM-1,beta-lactamase_0,P62593,1.13255,NO,36,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.732,-5.131,2.399,,0.555,H,A,0.75,1.17,13.689,13.689,77.62,AAP,-1.91167,0.0500837,0.00476483,1.13255 beta-lactamase_0_A34F,beta-lactamase_0_34,TEM-1,beta-lactamase_0,P62593,1.13257,NO,34,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.059,-3.937,1.878,,,H,A,0.46,-0.54,3.998,,73.78,AHA,-1.74967,0.0500837,0.00407913,1.13257 kka2_1:8_A56D,kka2_1:8_56,Kka2,kka2_1:8,P00552,1.13259,NO,56,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.083,-2.651,0.568,,0.796,T,A,0.46,1.39,10.511,,71.59,OHH,-1.86867,0.100394,0.00717715,1.13259 kka2_1:8_A56D,kka2_1:8_56,Kka2,kka2_1:8,P00552,1.13259,NO,56,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.083,-2.651,0.568,,0.796,T,A,0.46,1.39,10.511,,71.59,OHH,-1.86867,0.100394,0.00717715,1.13259 kka2_1:8_V80F,kka2_1:8_80,Kka2,kka2_1:8,P00552,1.13259,NO,80,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.144,-3.963,2.819,,0.358,E,B,1.48,-0.24,2.562,,63.64,HHH,-1.64633,0.100394,0.00488211,1.13259 kka2_1:8_V80F,kka2_1:8_80,Kka2,kka2_1:8,P00552,1.13259,NO,80,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.144,-3.963,2.819,,0.358,E,B,1.48,-0.24,2.562,,63.64,HHH,-1.64633,0.100394,0.00488211,1.13259 kka2_1:2_E111D,kka2_1:2_111,Kka2,kka2_1:2,P00552,1.13262,NO,111,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.28,-2.742,0.462,,0.155,H,A,1.52,-1.14,2.792,,65.53,HAB,-2.27833,0.295029,0.00746789,1.13262 kka2_1:4_H139R,kka2_1:4_139,Kka2,kka2_1:4,P00552,1.13266,NO,139,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-2.809,-2.657,-0.152,,0.471,H,A,0.17,0.68,12.761,12.761,63.64,BBB,-2.22,0.168804,0.00734779,1.13266 kka2_1:4_A56M,kka2_1:4_56,Kka2,kka2_1:4,P00552,1.13268,NO,56,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.083,-4.776,2.693,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.168804,0.00717715,1.13268 kka2_1:4_D154F,kka2_1:4_154,Kka2,kka2_1:4,P00552,1.13281,NO,154,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.876,-4.375,3.499,,0.457,,b,0.29,1.48,15.641,15.641,52.65,HAP,-1.52467,0.168804,0.00292633,1.13281 kka2_1:4_A137K,kka2_1:4_137,Kka2,kka2_1:4,P00552,1.13282,NO,137,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.156,-3.751,1.595,,0.029,H,A,0.46,0.34,2.227,,63.26,PHB,-2.559,0.168804,0.00515054,1.13282 kka2_1:4_D33R,kka2_1:4_33,Kka2,kka2_1:4,P00552,1.13288,NO,33,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.186,-2.468,0.282,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.168804,0.00633568,1.13288 beta-lactamase_0_H94F,beta-lactamase_0_94,TEM-1,beta-lactamase_0,P62593,1.13291,NO,94,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-2.5,-4.323,1.823,,0.776,,B,0.17,1.24,1.176,,77.62,HBH,-1.872,0.0500837,0.00389226,1.13291 PSD95pdz3_G335C,PSD95pdz3_335,PSD95pdz3,PSD95pdz3,P31016,1.13291,NO,335,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.008,-4.769,3.761,4.76223,,,,,22.4225,,,,AOH,-1.34733,0.0758425,0.000900493,1.13291 kka2_1:8_D227A,kka2_1:8_227,Kka2,kka2_1:8,P00552,1.13293,NO,227,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.758,-2.851,1.093,,0.128,H,A,0.75,-0.63,0.281,,56.06,BAH,-1.43067,0.100394,0.00745029,1.13293 kka2_1:8_D227A,kka2_1:8_227,Kka2,kka2_1:8,P00552,1.13293,NO,227,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.758,-2.851,1.093,,0.128,H,A,0.75,-0.63,0.281,,56.06,BAH,-1.43067,0.100394,0.00745029,1.13293 kka2_1:1_V242T,kka2_1:1_242,Kka2,kka2_1:1,P00552,1.13307,NO,242,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-2.687,-2.522,-0.165,,0.75,H,A,0.44,-0.37,4.987,,71.59,HHH,-2.16533,0.520039,0.0102575,1.13307 beta-lactamase_0_E272C,beta-lactamase_0_272,TEM-1,beta-lactamase_0,P62593,1.1331,NO,272,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.0500837,0.00545371,1.1331 kka2_1:2_I29L,kka2_1:2_29,Kka2,kka2_1:2,P00552,1.1331,NO,29,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.692,-1.88,0.188,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.295029,0.00619521,1.1331 kka2_1:4_L152R,kka2_1:4_152,Kka2,kka2_1:4,P00552,1.13314,NO,152,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.521,-2.523,1.002,,0.547,,A,1.59,1.36,2.318,,63.64,OHH,-1.162,0.168804,0.00674868,1.13314 kka2_1:4_L7N,kka2_1:4_7,Kka2,kka2_1:4,P00552,1.13314,NO,7,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.926,-3.49,1.564,,,,,,,3.012,,71.59,OHB,-2.12333,0.168804,0.00269456,1.13314 kka2_1:4_E160W,kka2_1:4_160,Kka2,kka2_1:4,P00552,1.13319,NO,160,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.683,-5.621,3.938,,0.989,G,A,1.04,2.28,2.531,,71.59,AAA,-1.36133,0.168804,0.00935762,1.13319 kka2_1:4_L165K,kka2_1:4_165,Kka2,kka2_1:4,P00552,1.1332,NO,165,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-2.453,-2.336,-0.117,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.168804,0.00801161,1.1332 kka2_1:4_E161A,kka2_1:4_161,Kka2,kka2_1:4,P00552,1.13327,NO,161,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.581,-1.927,0.346,,0.829,G,A,1.52,2.24,1.612,,92.05,AAB,-1.861,0.168804,0.00760103,1.13327 kka2_1:8_E17Q,kka2_1:8_17,Kka2,kka2_1:8,P00552,1.13328,NO,17,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.154,-2.533,0.379,,0.957,T,A,1.04,0.22,31.483,31.483,63.64,HAB,-2.432,0.100394,0.00688738,1.13328 kka2_1:8_E17Q,kka2_1:8_17,Kka2,kka2_1:8,P00552,1.13328,NO,17,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.154,-2.533,0.379,,0.957,T,A,1.04,0.22,31.483,31.483,63.64,HAB,-2.432,0.100394,0.00688738,1.13328 beta-lactamase_0_T269H,beta-lactamase_0_269,TEM-1,beta-lactamase_0,P62593,1.13337,NO,269,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.0500837,0.00950944,1.13337 kka2_1:4_R44G,kka2_1:4_44,Kka2,kka2_1:4,P00552,1.13354,NO,44,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.062,-2.106,0.044,,0.487,S,B,1.2,-0.35,5.71,,71.59,OBO,-1.80767,0.168804,0.00745043,1.13354 kka2_1:8_A166M,kka2_1:8_166,Kka2,kka2_1:8,P00552,1.13354,NO,166,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.407,-4.784,2.377,,0.534,,B,1.04,1.03,13.995,13.995,71.59,HHO,-2.421,0.100394,0.00799912,1.13354 kka2_1:8_A166M,kka2_1:8_166,Kka2,kka2_1:8,P00552,1.13354,NO,166,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.407,-4.784,2.377,,0.534,,B,1.04,1.03,13.995,13.995,71.59,HHO,-2.421,0.100394,0.00799912,1.13354 kka2_1:4_V46M,kka2_1:4_46,Kka2,kka2_1:4,P00552,1.13355,NO,46,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-2.62,-3.643,1.023,,0.192,.,B,0.44,-1.12,9.564,,92.05,OHH,-1.88633,0.168804,0.00631301,1.13355 beta-lactamase_0_R159H,beta-lactamase_0_159,TEM-1,beta-lactamase_0,P62593,1.13373,NO,159,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-0.94,-2.789,1.849,,0.316,,B,1.2,-0.55,1.426,,64.34,PBH,-1.011,0.0500837,0.00108472,1.13373 kka2_1:4_D250V,kka2_1:4_250,Kka2,kka2_1:4,P00552,1.13378,NO,250,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.015,-3.813,2.798,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.168804,0.0177103,1.13378 kka2_1:4_I141M,kka2_1:4_141,Kka2,kka2_1:4,P00552,1.13382,NO,141,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.495,-2.864,1.369,,0.068,H,A,0.48,-0.01,2.144,,92.05,BHA,-1.689,0.168804,0.00744745,1.13382 kka2_1:8_A150W,kka2_1:8_150,Kka2,kka2_1:8,P00552,1.13384,NO,150,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.949,-5.375,4.426,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.100394,0.0045009,1.13384 kka2_1:8_A150W,kka2_1:8_150,Kka2,kka2_1:8,P00552,1.13384,NO,150,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.949,-5.375,4.426,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.100394,0.0045009,1.13384 kka2_1:8_S114C,kka2_1:8_114,Kka2,kka2_1:8,P00552,1.13388,NO,114,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.527,-5.142,2.615,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.100394,0.00705262,1.13388 kka2_1:8_S114C,kka2_1:8_114,Kka2,kka2_1:8,P00552,1.13388,NO,114,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.527,-5.142,2.615,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.100394,0.00705262,1.13388 kka2_1:8_P179F,kka2_1:8_179,Kka2,kka2_1:8,P00552,1.13393,NO,179,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.974,-4.355,3.381,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.100394,0.00298346,1.13393 kka2_1:8_P179F,kka2_1:8_179,Kka2,kka2_1:8,P00552,1.13393,NO,179,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.974,-4.355,3.381,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.100394,0.00298346,1.13393 beta-lactamase_0_G236Q,beta-lactamase_0_236,TEM-1,beta-lactamase_0,P62593,1.13394,NO,236,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.784,-4.093,3.309,,0.241,,b,0.29,-0.59,3.506,,64.69,HOO,-1.025,0.0500837,0.00162372,1.13394 kka2_1:8_S11Y,kka2_1:8_11,Kka2,kka2_1:8,P00552,1.13397,NO,11,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.322,-4.097,1.775,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.100394,0.00381691,1.13397 kka2_1:8_S11Y,kka2_1:8_11,Kka2,kka2_1:8,P00552,1.13397,NO,11,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.322,-4.097,1.775,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.100394,0.00381691,1.13397 kka2_1:8_A56H,kka2_1:8_56,Kka2,kka2_1:8,P00552,1.13401,NO,56,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.083,-4.875,2.792,,0.796,T,A,0.46,1.39,10.511,,71.59,OHH,-1.86867,0.100394,0.00717715,1.13401 kka2_1:8_A56H,kka2_1:8_56,Kka2,kka2_1:8,P00552,1.13401,NO,56,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.083,-4.875,2.792,,0.796,T,A,0.46,1.39,10.511,,71.59,OHH,-1.86867,0.100394,0.00717715,1.13401 kka2_1:8_L152R,kka2_1:8_152,Kka2,kka2_1:8,P00552,1.13402,NO,152,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.521,-2.523,1.002,,0.547,.,A,0.55,1.36,1.442,,63.64,OHH,-1.162,0.100394,0.00674868,1.13402 kka2_1:8_L152R,kka2_1:8_152,Kka2,kka2_1:8,P00552,1.13402,NO,152,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.521,-2.523,1.002,,0.547,.,A,0.55,1.36,1.442,,63.64,OHH,-1.162,0.100394,0.00674868,1.13402 kka2_1:8_H8W,kka2_1:8_8,Kka2,kka2_1:8,P00552,1.13403,NO,8,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-2.759,-5.188,2.429,,,,,,,,,71.59,HBH,-2.25467,0.100394,0.00256422,1.13403 kka2_1:8_H8W,kka2_1:8_8,Kka2,kka2_1:8,P00552,1.13403,NO,8,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-2.759,-5.188,2.429,,,,,,,,,71.59,HBH,-2.25467,0.100394,0.00256422,1.13403 kka2_1:4_A137Y,kka2_1:4_137,Kka2,kka2_1:4,P00552,1.13406,NO,137,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.156,-4.084,1.928,,0.029,H,A,0.46,0.34,2.227,,63.26,PHB,-2.559,0.168804,0.00515054,1.13406 kka2_1:2_Y218W,kka2_1:2_218,Kka2,kka2_1:2,P00552,1.13408,NO,218,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-1.438,-3.229,1.791,,0.122,H,A,0.21,-0.69,1.022,,56.06,BHP,-1.17533,0.295029,0.0126098,1.13408 kka2_1:8_I196V,kka2_1:8_196,Kka2,kka2_1:8,P00552,1.13415,NO,196,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-2.115,-2.455,0.34,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.100394,0.0107273,1.13415 kka2_1:8_I196V,kka2_1:8_196,Kka2,kka2_1:8,P00552,1.13415,NO,196,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-2.115,-2.455,0.34,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.100394,0.0107273,1.13415 kka2_1:8_T146Y,kka2_1:8_146,Kka2,kka2_1:8,P00552,1.13416,NO,146,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.978,-4.381,1.403,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.100394,0.00606474,1.13416 kka2_1:8_T146Y,kka2_1:8_146,Kka2,kka2_1:8,P00552,1.13416,NO,146,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.978,-4.381,1.403,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.100394,0.00606474,1.13416 kka2_1:4_D134P,kka2_1:4_134,Kka2,kka2_1:4,P00552,1.13417,NO,134,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.969,-3.811,2.842,,0.421,B,B,0.75,0.31,0.733,,49.62,HAB,-1.057,0.168804,0.00270812,1.13417 kka2_1:2_D33E,kka2_1:2_33,Kka2,kka2_1:2,P00552,1.13423,NO,33,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.186,-2.762,0.576,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.295029,0.00633568,1.13423 kka2_1:4_A87V,kka2_1:4_87,Kka2,kka2_1:4,P00552,1.13423,NO,87,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.917,-3.732,1.815,,1.039,S,L,0.46,1.57,22.675,22.675,65.53,AHO,-1.822,0.168804,0.00791281,1.13423 beta-lactamase_0_E102C,beta-lactamase_0_102,TEM-1,beta-lactamase_0,P62593,1.13426,NO,102,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.118,-5.064,2.946,,0.722,S,B,1.04,1.82,4.773,,73.08,HAH,-1.581,0.0500837,0.00486633,1.13426 kka2_1:8_L165R,kka2_1:8_165,Kka2,kka2_1:8,P00552,1.13426,NO,165,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-2.453,-2.067,-0.386,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.100394,0.00801161,1.13426 kka2_1:8_L165R,kka2_1:8_165,Kka2,kka2_1:8,P00552,1.13426,NO,165,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-2.453,-2.067,-0.386,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.100394,0.00801161,1.13426 beta-lactamase_0_D129Q,beta-lactamase_0_129,TEM-1,beta-lactamase_0,P62593,1.1343,NO,129,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.816,-3.637,2.821,,,,B,0.75,-0.69,2.66,,34.97,PAP,-0.818,0.0500837,0.00109178,1.1343 kka2_1:8_S105A,kka2_1:8_105,Kka2,kka2_1:8,P00552,1.13445,NO,105,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.945,-1.746,-0.199,,0.056,S,B,0.27,-1.04,2.115,,65.53,PPB,-2.17033,0.100394,0.00847233,1.13445 kka2_1:8_S105A,kka2_1:8_105,Kka2,kka2_1:8,P00552,1.13445,NO,105,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.945,-1.746,-0.199,,0.056,S,B,0.27,-1.04,2.115,,65.53,PPB,-2.17033,0.100394,0.00847233,1.13445 beta-lactamase_0_I258K,beta-lactamase_0_258,TEM-1,beta-lactamase_0,P62593,1.13447,NO,258,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.0500837,0.007931,1.13447 kka2_1:1_D52C,kka2_1:1_52,Kka2,kka2_1:1,P00552,1.13448,NO,52,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.271,-5.339,3.068,,0.22,E,B,0.75,0.8,2.64,,71.59,PAH,-2.38367,0.520039,0.00175694,1.13448 beta-lactamase_0_E102P,beta-lactamase_0_102,TEM-1,beta-lactamase_0,P62593,1.13451,NO,102,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.118,-3.88,1.762,,0.722,S,B,1.04,1.82,4.773,,73.08,HAH,-1.581,0.0500837,0.00486633,1.13451 kka2_1:4_A87C,kka2_1:4_87,Kka2,kka2_1:4,P00552,1.13452,NO,87,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.917,-5.153,3.236,,1.039,S,L,0.46,1.57,22.675,22.675,65.53,AHO,-1.822,0.168804,0.00791281,1.13452 kka2_1:8_F171M,kka2_1:8_171,Kka2,kka2_1:8,P00552,1.13452,NO,171,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.326,-4.328,3.002,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.100394,0.00821426,1.13452 kka2_1:8_F171M,kka2_1:8_171,Kka2,kka2_1:8,P00552,1.13452,NO,171,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.326,-4.328,3.002,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.100394,0.00821426,1.13452 WW_domain_D170Q,WW_domain_170,Yap65,WW_domain,P46937,1.13452,NO,170,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.213,-3.364,2.151,,,,,,,0.399,,15.87,OAH,-1.38,0.153962,0.00123319,1.13452 beta-lactamase_0_M153V,beta-lactamase_0_153,TEM-1,beta-lactamase_0,P62593,1.13453,NO,153,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-3.193,-2.524,-0.669,,0.14,T,A,0.55,-0.11,3.826,,77.62,PHO,-2.25767,0.0500837,0.00509109,1.13453 kka2_1:8_S114T,kka2_1:8_114,Kka2,kka2_1:8,P00552,1.13454,NO,114,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.527,-2.564,0.037,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.100394,0.00705262,1.13454 kka2_1:8_S114T,kka2_1:8_114,Kka2,kka2_1:8,P00552,1.13454,NO,114,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.527,-2.564,0.037,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.100394,0.00705262,1.13454 kka2_1:8_A248G,kka2_1:8_248,Kka2,kka2_1:8,P00552,1.13474,NO,248,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.124,-2.636,0.512,,0.825,S,b,1.04,0.46,11.329,11.329,92.05,HHO,-2.15,0.100394,0.0125484,1.13474 kka2_1:8_A248G,kka2_1:8_248,Kka2,kka2_1:8,P00552,1.13474,NO,248,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.124,-2.636,0.512,,0.825,S,b,1.04,0.46,11.329,11.329,92.05,HHO,-2.15,0.100394,0.0125484,1.13474 beta-lactamase_0_Q267T,beta-lactamase_0_267,TEM-1,beta-lactamase_0,P62593,1.1348,NO,267,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.308,-3.09,0.782,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.0500837,0.0102128,1.1348 kka2_1:4_N200H,kka2_1:4_200,Kka2,kka2_1:4,P00552,1.13484,NO,200,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-2.446,-3.247,0.801,,0.756,T,L,0.61,-0.08,1.746,,64.39,APO,-2.08,0.168804,0.00838549,1.13484 kka2_1:2_G10L,kka2_1:2_10,Kka2,kka2_1:2,P00552,1.1349,NO,10,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.921,-3.61,1.689,,,,,,,2.192,,71.59,HOP,-2.10733,0.295029,0.00289233,1.1349 kka2_1:4_G74A,kka2_1:4_74,Kka2,kka2_1:4,P00552,1.13492,NO,74,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.18,-3.17,1.99,,0.621,T,l,0.75,0.2,1.032,,64.39,POH,-1.91667,0.168804,0.00587035,1.13492 kka2_1:8_R253L,kka2_1:8_253,Kka2,kka2_1:8,P00552,1.13494,NO,253,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.356,-3.455,2.099,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.100394,0.0144195,1.13494 kka2_1:8_R253L,kka2_1:8_253,Kka2,kka2_1:8,P00552,1.13494,NO,253,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.356,-3.455,2.099,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.100394,0.0144195,1.13494 kka2_1:1_I2L,kka2_1:1_2,Kka2,kka2_1:1,P00552,1.13497,NO,2,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.787,-2.519,0.732,,,,,,,2.329,,71.59,HHA,-1.92433,0.520039,0.00246644,1.13497 kka2_1:8_F20L,kka2_1:8_20,Kka2,kka2_1:8,P00552,1.135,NO,20,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-3.354,-3.523,0.169,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.100394,0.00701744,1.135 kka2_1:8_F20L,kka2_1:8_20,Kka2,kka2_1:8,P00552,1.135,NO,20,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-3.354,-3.523,0.169,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.100394,0.00701744,1.135 kka2_1:4_A129D,kka2_1:4_129,Kka2,kka2_1:4,P00552,1.13501,NO,129,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.656,-2.499,0.843,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.168804,0.00726862,1.13501 beta-lactamase_0_F58L,beta-lactamase_0_58,TEM-1,beta-lactamase_0,P62593,1.13503,NO,58,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-2.914,-3.474,0.56,,0.266,E,B,0.58,-0.07,24.637,24.637,77.62,PHB,-2.059,0.0500837,0.00523369,1.13503 beta-lactamase_0_T147C,beta-lactamase_0_147,TEM-1,beta-lactamase_0,P62593,1.13507,NO,147,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.149,-4.804,3.655,,0.281,H,A,0.22,-0.68,3.487,,64.34,HPH,-1.456,0.0500837,0.00226017,1.13507 kka2_1:8_S105C,kka2_1:8_105,Kka2,kka2_1:8,P00552,1.13507,NO,105,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.945,-3.198,1.253,,0.056,S,B,0.27,-1.04,2.115,,65.53,PPB,-2.17033,0.100394,0.00847233,1.13507 kka2_1:8_S105C,kka2_1:8_105,Kka2,kka2_1:8,P00552,1.13507,NO,105,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.945,-3.198,1.253,,0.056,S,B,0.27,-1.04,2.115,,65.53,PPB,-2.17033,0.100394,0.00847233,1.13507 kka2_1:8_L57R,kka2_1:8_57,Kka2,kka2_1:8,P00552,1.13508,NO,57,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.898,-4.138,2.24,,0.343,T,A,0.55,0.98,13.359,13.359,52.65,HHP,-2.20733,0.100394,0.00723769,1.13508 kka2_1:8_L57R,kka2_1:8_57,Kka2,kka2_1:8,P00552,1.13508,NO,57,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.898,-4.138,2.24,,0.343,T,A,0.55,0.98,13.359,13.359,52.65,HHP,-2.20733,0.100394,0.00723769,1.13508 kka2_1:8_Q26E,kka2_1:8_26,Kka2,kka2_1:8,P00552,1.13508,NO,26,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.18,-2.898,0.718,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.100394,0.00708962,1.13508 kka2_1:8_Q26E,kka2_1:8_26,Kka2,kka2_1:8,P00552,1.13508,NO,26,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.18,-2.898,0.718,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.100394,0.00708962,1.13508 kka2_1:8_D33R,kka2_1:8_33,Kka2,kka2_1:8,P00552,1.13509,NO,33,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.186,-2.468,0.282,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.100394,0.00633568,1.13509 kka2_1:8_D33R,kka2_1:8_33,Kka2,kka2_1:8,P00552,1.13509,NO,33,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.186,-2.468,0.282,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.100394,0.00633568,1.13509 kka2_1:8_Q155R,kka2_1:8_155,Kka2,kka2_1:8,P00552,1.13512,NO,155,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.606,-3.728,1.122,,0.525,T,A,0.64,1.49,,,63.64,APA,-1.726,0.100394,0.00641853,1.13512 kka2_1:8_Q155R,kka2_1:8_155,Kka2,kka2_1:8,P00552,1.13512,NO,155,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.606,-3.728,1.122,,0.525,T,A,0.64,1.49,,,63.64,APA,-1.726,0.100394,0.00641853,1.13512 kka2_1:8_G181Q,kka2_1:8_181,Kka2,kka2_1:8,P00552,1.13515,NO,181,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-2.698,-2.961,0.263,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.100394,0.00728319,1.13515 kka2_1:8_G181Q,kka2_1:8_181,Kka2,kka2_1:8,P00552,1.13515,NO,181,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-2.698,-2.961,0.263,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.100394,0.00728319,1.13515 kka2_1:2_P45D,kka2_1:2_45,Kka2,kka2_1:2,P00552,1.13532,NO,45,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.774,-3.026,1.252,,0.669,,B,0.52,-0.76,4.882,,71.59,BOH,-2.152,0.295029,0.00590481,1.13532 beta-lactamase_0_N50K,beta-lactamase_0_50,TEM-1,beta-lactamase_0,P62593,1.13539,NO,50,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-2.979,-3.578,0.599,,0.912,T,A,0.61,1.24,9.874,9.874,77.62,HPP,-2.134,0.0500837,0.0047211,1.13539 beta-lactamase_0_A278K,beta-lactamase_0_278,TEM-1,beta-lactamase_0,P62593,1.13544,NO,278,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.348,,,,0.015,H,A,0.48,-0.85,4.624,,63.29,HHA,-1.41833,0.0500837,0.0310297,1.13544 kka2_1:8_I207V,kka2_1:8_207,Kka2,kka2_1:8,P00552,1.13544,NO,207,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.175,-1.613,0.438,,0.293,,B,1.52,-1.12,1.306,,56.06,HHA,-1.07733,0.100394,0.00611824,1.13544 kka2_1:8_I207V,kka2_1:8_207,Kka2,kka2_1:8,P00552,1.13544,NO,207,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.175,-1.613,0.438,,0.293,,B,1.52,-1.12,1.306,,56.06,HHA,-1.07733,0.100394,0.00611824,1.13544 kka2_1:8_D238V,kka2_1:8_238,Kka2,kka2_1:8,P00552,1.13546,NO,238,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.83,-3.676,0.846,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.100394,0.0113863,1.13546 kka2_1:8_D238V,kka2_1:8_238,Kka2,kka2_1:8,P00552,1.13546,NO,238,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.83,-3.676,0.846,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.100394,0.0113863,1.13546 WW_domain_D194S,WW_domain_194,Yap65,WW_domain,P46937,1.13546,NO,194,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.536,-3.125,1.589,5.95614,,,,,,1.948,,74.4,HAP,-1.78933,0.153962,0.00483742,1.13546 beta-lactamase_0_L74M,beta-lactamase_0_74,TEM-1,beta-lactamase_0,P62593,1.13549,NO,74,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.296,-2.987,1.691,,,H,A,0.55,-0.91,1.46,,50,HHO,-1.34933,0.0500837,0.00493255,1.13549 kka2_1:4_E160K,kka2_1:4_160,Kka2,kka2_1:4,P00552,1.13552,NO,160,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.683,-2.805,1.122,,0.989,G,A,1.04,2.28,2.531,,71.59,AAA,-1.36133,0.168804,0.00935762,1.13552 kka2_1:2_P249V,kka2_1:2_249,Kka2,kka2_1:2,P00552,1.13559,NO,249,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.867,-2.403,0.536,,0.406,.,B,0.52,-0.01,0.76,,92.05,HOA,-1.66867,0.295029,0.011045,1.13559 kka2_1:8_G234F,kka2_1:8_234,Kka2,kka2_1:8,P00552,1.1356,NO,234,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-2.9,-4.504,1.604,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.100394,0.00984449,1.1356 kka2_1:8_G234F,kka2_1:8_234,Kka2,kka2_1:8,P00552,1.1356,NO,234,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-2.9,-4.504,1.604,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.100394,0.00984449,1.1356 beta-lactamase_0_M270H,beta-lactamase_0_270,TEM-1,beta-lactamase_0,P62593,1.13566,NO,270,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.0500837,0.00767762,1.13566 beta-lactamase_0_S80Y,beta-lactamase_0_80,TEM-1,beta-lactamase_0,P62593,1.13566,NO,80,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.029,-4.297,2.268,,0.192,H,A,0.27,0.46,12.403,12.403,77.62,HPB,-1.44567,0.0500837,0.00565569,1.13566 kka2_1:8_A56E,kka2_1:8_56,Kka2,kka2_1:8,P00552,1.13569,NO,56,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.083,-2.646,0.563,,0.796,T,A,0.46,1.39,10.511,,71.59,OHH,-1.86867,0.100394,0.00717715,1.13569 kka2_1:8_A56E,kka2_1:8_56,Kka2,kka2_1:8,P00552,1.13569,NO,56,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.083,-2.646,0.563,,0.796,T,A,0.46,1.39,10.511,,71.59,OHH,-1.86867,0.100394,0.00717715,1.13569 beta-lactamase_0_H110A,beta-lactamase_0_110,TEM-1,beta-lactamase_0,P62593,1.13588,NO,110,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-1.706,-3.353,1.647,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.0500837,0.00441499,1.13588 kka2_1:2_E160A,kka2_1:2_160,Kka2,kka2_1:2,P00552,1.13589,NO,160,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.683,-2.356,0.673,,0.989,G,A,1.04,2.28,3.948,,71.59,AAA,-1.36133,0.295029,0.00935762,1.13589 kka2_1:4_G95A,kka2_1:4_95,Kka2,kka2_1:4,P00552,1.1359,NO,95,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-2.403,-3.101,0.698,,0.126,E,B,0.29,-0.74,0.359,,71.59,HOA,-2.198,0.168804,0.00743616,1.1359 beta-lactamase_0_A84L,beta-lactamase_0_84,TEM-1,beta-lactamase_0,P62593,1.13595,NO,84,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.651,-3.508,1.857,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.0500837,0.00503822,1.13595 kka2_1:8_G10F,kka2_1:8_10,Kka2,kka2_1:8,P00552,1.13607,NO,10,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.921,-4.367,2.446,,,,,,,1.862,,71.59,HOP,-2.10733,0.100394,0.00289233,1.13607 kka2_1:8_G10F,kka2_1:8_10,Kka2,kka2_1:8,P00552,1.13607,NO,10,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.921,-4.367,2.446,,,,,,,1.862,,71.59,HOP,-2.10733,0.100394,0.00289233,1.13607 kka2_1:8_G95R,kka2_1:8_95,Kka2,kka2_1:8,P00552,1.13625,NO,95,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-2.403,-3.111,0.708,,0.126,E,B,0.75,-0.74,7.774,,71.59,HOA,-2.198,0.100394,0.00743616,1.13625 kka2_1:8_G95R,kka2_1:8_95,Kka2,kka2_1:8,P00552,1.13625,NO,95,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-2.403,-3.111,0.708,,0.126,E,B,0.75,-0.74,7.774,,71.59,HOA,-2.198,0.100394,0.00743616,1.13625 beta-lactamase_0_E145F,beta-lactamase_0_145,TEM-1,beta-lactamase_0,P62593,1.13636,NO,145,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.357,-4.373,2.016,,0.545,H,A,1.04,0.79,1.199,,77.62,BAH,-2.069,0.0500837,0.00553285,1.13636 kka2_1:2_K138Q,kka2_1:2_138,Kka2,kka2_1:2,P00552,1.13637,NO,138,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-2.5,-2.969,0.469,,0.594,H,A,2.34,0.98,21.038,21.038,71.59,HBB,-2.48833,0.295029,0.00628542,1.13637 kka2_1:8_I246S,kka2_1:8_246,Kka2,kka2_1:8,P00552,1.13645,NO,246,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-2.008,-3.645,1.637,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.100394,0.0139479,1.13645 kka2_1:8_I246S,kka2_1:8_246,Kka2,kka2_1:8,P00552,1.13645,NO,246,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-2.008,-3.645,1.637,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.100394,0.0139479,1.13645 beta-lactamase_0_M67H,beta-lactamase_0_67,TEM-1,beta-lactamase_0,P62593,1.13648,NO,67,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-2.231,-4.763,2.532,,0.006,G,P,0.55,-0.81,24.165,24.165,65.03,HHP,-1.502,0.0500837,0.00409753,1.13648 kka2_1:8_E231F,kka2_1:8_231,Kka2,kka2_1:8,P00552,1.13656,NO,231,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.002,-4.394,2.392,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.100394,0.00732383,1.13656 kka2_1:8_E231F,kka2_1:8_231,Kka2,kka2_1:8,P00552,1.13656,NO,231,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.002,-4.394,2.392,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.100394,0.00732383,1.13656 PSD95pdz3_P311T,PSD95pdz3_311,PSD95pdz3,PSD95pdz3,P31016,1.13659,NO,311,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.236,-3.103,1.867,5.76649,,,,,14.78,,,,OOB,-1.409,0.0758425,0.0030796,1.13659 kka2_1:1_D5A,kka2_1:1_5,Kka2,kka2_1:1,P00552,1.13663,NO,5,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.306,-3.033,1.727,,,,,,,0.895,,71.59,PAO,-1.784,0.520039,0.00222864,1.13663 kka2_1:8_E161A,kka2_1:8_161,Kka2,kka2_1:8,P00552,1.13664,NO,161,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.581,-1.927,0.346,,0.829,G,A,1.04,2.24,11.923,11.923,92.05,AAB,-1.861,0.100394,0.00760103,1.13664 kka2_1:8_E161A,kka2_1:8_161,Kka2,kka2_1:8,P00552,1.13664,NO,161,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.581,-1.927,0.346,,0.829,G,A,1.04,2.24,11.923,11.923,92.05,AAB,-1.861,0.100394,0.00760103,1.13664 kka2_1:8_Q27S,kka2_1:8_27,Kka2,kka2_1:8,P00552,1.13669,NO,27,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-1.659,-3.464,1.805,,0.608,.,A,0.64,0.71,3.919,,65.53,PPP,-1.90733,0.100394,0.00595365,1.13669 kka2_1:8_Q27S,kka2_1:8_27,Kka2,kka2_1:8,P00552,1.13669,NO,27,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-1.659,-3.464,1.805,,0.608,.,A,0.64,0.71,3.919,,65.53,PPP,-1.90733,0.100394,0.00595365,1.13669 kka2_1:2_K175M,kka2_1:2_175,Kka2,kka2_1:2,P00552,1.13676,NO,175,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-2.897,-3.26,0.363,,0.579,H,A,1.3,0.51,15.629,15.629,71.59,HBH,-1.82333,0.295029,0.00693093,1.13676 kka2_1:8_C31R,kka2_1:8_31,Kka2,kka2_1:8,P00552,1.13683,NO,31,C,R,CR,Special,PositiveCharge,5.07,6.34148,1.27148,180,121,174,53,108.5,173.4,64.9,-2.246,-1.901,-0.345,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.100394,0.00681582,1.13683 kka2_1:8_C31R,kka2_1:8_31,Kka2,kka2_1:8,P00552,1.13683,NO,31,C,R,CR,Special,PositiveCharge,5.07,6.34148,1.27148,180,121,174,53,108.5,173.4,64.9,-2.246,-1.901,-0.345,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.100394,0.00681582,1.13683 kka2_1:2_E199D,kka2_1:2_199,Kka2,kka2_1:2,P00552,1.13687,NO,199,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.234,-2.172,-0.062,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.295029,0.00854122,1.13687 kka2_1:8_A229R,kka2_1:8_229,Kka2,kka2_1:8,P00552,1.13694,NO,229,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.739,-2.242,0.503,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.100394,0.00942138,1.13694 kka2_1:8_A229R,kka2_1:8_229,Kka2,kka2_1:8,P00552,1.13694,NO,229,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.739,-2.242,0.503,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.100394,0.00942138,1.13694 kka2_1:8_G10W,kka2_1:8_10,Kka2,kka2_1:8,P00552,1.13701,NO,10,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.921,-5.359,3.438,,,,,,,1.862,,71.59,HOP,-2.10733,0.100394,0.00289233,1.13701 kka2_1:8_G10W,kka2_1:8_10,Kka2,kka2_1:8,P00552,1.13701,NO,10,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.921,-5.359,3.438,,,,,,,1.862,,71.59,HOP,-2.10733,0.100394,0.00289233,1.13701 beta-lactamase_0_K109T,beta-lactamase_0_109,TEM-1,beta-lactamase_0,P62593,1.13705,NO,109,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.734,-2.559,0.825,,0.787,G,A,2.34,2.21,15.473,15.473,72.73,ABB,-1.63333,0.0500837,0.00462493,1.13705 kka2_1:4_E231V,kka2_1:4_231,Kka2,kka2_1:4,P00552,1.13706,NO,231,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.002,-2.912,0.91,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.168804,0.00732383,1.13706 kka2_1:8_A78C,kka2_1:8_78,Kka2,kka2_1:8,P00552,1.13706,NO,78,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.744,-4.918,3.174,,0.078,,B,1.04,-0.53,1.251,,56.06,OHH,-1.863,0.100394,0.00457299,1.13706 kka2_1:8_A78C,kka2_1:8_78,Kka2,kka2_1:8,P00552,1.13706,NO,78,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.744,-4.918,3.174,,0.078,,B,1.04,-0.53,1.251,,56.06,OHH,-1.863,0.100394,0.00457299,1.13706 kka2_1:2_I2D,kka2_1:2_2,Kka2,kka2_1:2,P00552,1.13708,NO,2,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.787,-3.608,1.821,,,,,,,5.773,,71.59,HHA,-1.92433,0.295029,0.00246644,1.13708 kka2_1:8_A255D,kka2_1:8_255,Kka2,kka2_1:8,P00552,1.13708,NO,255,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.715,-2.352,0.637,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.100394,0.0126809,1.13708 kka2_1:8_A255D,kka2_1:8_255,Kka2,kka2_1:8,P00552,1.13708,NO,255,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.715,-2.352,0.637,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.100394,0.0126809,1.13708 kka2_1:4_V46F,kka2_1:4_46,Kka2,kka2_1:4,P00552,1.13712,NO,46,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-2.62,-3.464,0.844,,0.192,.,B,0.44,-1.12,9.564,,92.05,OHH,-1.88633,0.168804,0.00631301,1.13712 kka2_1:4_Y244L,kka2_1:4_244,Kka2,kka2_1:4,P00552,1.13715,NO,244,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-0.775,-3.161,2.386,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.168804,0.00453187,1.13715 kka2_1:8_H139Q,kka2_1:8_139,Kka2,kka2_1:8,P00552,1.13718,NO,139,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-2.809,-2.861,0.052,,0.471,H,A,0.17,0.68,28.583,28.583,63.64,BBB,-2.22,0.100394,0.00734779,1.13718 kka2_1:8_H139Q,kka2_1:8_139,Kka2,kka2_1:8,P00552,1.13718,NO,139,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-2.809,-2.861,0.052,,0.471,H,A,0.17,0.68,28.583,28.583,63.64,BBB,-2.22,0.100394,0.00734779,1.13718 kka2_1:4_V75S,kka2_1:4_75,Kka2,kka2_1:4,P00552,1.13725,NO,75,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-2.06,-3.699,1.639,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.168804,0.00693733,1.13725 kka2_1:8_S11W,kka2_1:8_11,Kka2,kka2_1:8,P00552,1.13727,NO,11,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.322,-5.275,2.953,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.100394,0.00381691,1.13727 kka2_1:8_S11W,kka2_1:8_11,Kka2,kka2_1:8,P00552,1.13727,NO,11,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.322,-5.275,2.953,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.100394,0.00381691,1.13727 beta-lactamase_0_A34D,beta-lactamase_0_34,TEM-1,beta-lactamase_0,P62593,1.13734,NO,34,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.059,-3.876,1.817,,,H,A,0.46,-0.54,3.998,,73.78,AHA,-1.74967,0.0500837,0.00407913,1.13734 beta-lactamase_0_E166W,beta-lactamase_0_166,TEM-1,beta-lactamase_0,P62593,1.13737,NO,166,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.756,-5.495,3.739,,0.508,G,A,1.04,1.05,17.227,17.227,73.08,OAH,-1.42233,0.0500837,0.00512989,1.13737 kka2_1:8_A191Y,kka2_1:8_191,Kka2,kka2_1:8,P00552,1.13737,NO,191,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.831,-4.254,3.423,,,,b,1.04,-0.94,1.306,,50,AHO,-0.868667,0.100394,0.00338807,1.13737 kka2_1:8_A191Y,kka2_1:8_191,Kka2,kka2_1:8,P00552,1.13737,NO,191,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.831,-4.254,3.423,,,,b,1.04,-0.94,1.306,,50,AHO,-0.868667,0.100394,0.00338807,1.13737 kka2_1:8_L103I,kka2_1:8_103,Kka2,kka2_1:8,P00552,1.13738,NO,103,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-2.362,-3.505,1.143,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.100394,0.00574792,1.13738 kka2_1:8_L103I,kka2_1:8_103,Kka2,kka2_1:8,P00552,1.13738,NO,103,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-2.362,-3.505,1.143,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.100394,0.00574792,1.13738 kka2_1:8_I196F,kka2_1:8_196,Kka2,kka2_1:8,P00552,1.1374,NO,196,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-2.115,-1.503,-0.612,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.100394,0.0107273,1.1374 kka2_1:8_I196F,kka2_1:8_196,Kka2,kka2_1:8,P00552,1.1374,NO,196,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-2.115,-1.503,-0.612,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.100394,0.0107273,1.1374 beta-lactamase_0_E87P,beta-lactamase_0_87,TEM-1,beta-lactamase_0,P62593,1.13745,NO,87,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.421,-3.872,2.451,,0.048,,B,1.04,0.92,1.159,,64.69,PAP,-1.969,0.0500837,0.00337888,1.13745 kka2_1:2_E142M,kka2_1:2_142,Kka2,kka2_1:2,P00552,1.13748,NO,142,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.221,-4.819,2.598,,0.471,H,A,1.52,0.85,3.693,,65.53,HAB,-2.08033,0.295029,0.00748883,1.13748 beta-lactamase_0_E102W,beta-lactamase_0_102,TEM-1,beta-lactamase_0,P62593,1.13754,NO,102,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.118,-5.479,3.361,,0.722,S,B,1.04,1.82,4.773,,73.08,HAH,-1.581,0.0500837,0.00486633,1.13754 kka2_1:4_D33Q,kka2_1:4_33,Kka2,kka2_1:4,P00552,1.13758,NO,33,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.186,-3.005,0.819,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.168804,0.00633568,1.13758 kka2_1:8_A247Y,kka2_1:8_247,Kka2,kka2_1:8,P00552,1.13761,NO,247,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.459,-4.278,1.819,,1.01,S,A,0.46,0.65,18.904,18.904,92.05,HHH,-2.197,0.100394,0.0102428,1.13761 kka2_1:8_A247Y,kka2_1:8_247,Kka2,kka2_1:8,P00552,1.13761,NO,247,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.459,-4.278,1.819,,1.01,S,A,0.46,0.65,18.904,18.904,92.05,HHH,-2.197,0.100394,0.0102428,1.13761 kka2_1:8_E161M,kka2_1:8_161,Kka2,kka2_1:8,P00552,1.13762,NO,161,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.581,-4.788,3.207,,0.829,G,A,1.04,2.24,11.923,11.923,92.05,AAB,-1.861,0.100394,0.00760103,1.13762 kka2_1:8_E161M,kka2_1:8_161,Kka2,kka2_1:8,P00552,1.13762,NO,161,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.581,-4.788,3.207,,0.829,G,A,1.04,2.24,11.923,11.923,92.05,AAB,-1.861,0.100394,0.00760103,1.13762 beta-lactamase_0_E145Y,beta-lactamase_0_145,TEM-1,beta-lactamase_0,P62593,1.13763,NO,145,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.357,-4.381,2.024,,0.545,H,A,1.04,0.79,1.199,,77.62,BAH,-2.069,0.0500837,0.00553285,1.13763 kka2_1:1_G234H,kka2_1:1_234,Kka2,kka2_1:1,P00552,1.13764,NO,234,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-2.9,-4.698,1.798,,0.494,H,A,0.29,-0.29,1.753,,71.59,OOA,-1.86767,0.520039,0.00984449,1.13764 kka2_1:8_G55M,kka2_1:8_55,Kka2,kka2_1:8,P00552,1.13764,NO,55,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.625,-3.536,1.911,,0.517,S,b,0.29,1.19,8.881,,63.64,POH,-2.05967,0.100394,0.00667877,1.13764 kka2_1:8_G55M,kka2_1:8_55,Kka2,kka2_1:8,P00552,1.13764,NO,55,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.625,-3.536,1.911,,0.517,S,b,0.29,1.19,8.881,,63.64,POH,-2.05967,0.100394,0.00667877,1.13764 kka2_1:8_E160F,kka2_1:8_160,Kka2,kka2_1:8,P00552,1.13769,NO,160,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.683,-4.47,2.787,,0.989,G,A,1.04,2.28,2.164,,71.59,AAA,-1.36133,0.100394,0.00935762,1.13769 kka2_1:8_E160F,kka2_1:8_160,Kka2,kka2_1:8,P00552,1.13769,NO,160,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.683,-4.47,2.787,,0.989,G,A,1.04,2.28,2.164,,71.59,AAA,-1.36133,0.100394,0.00935762,1.13769 kka2_1:2_R173T,kka2_1:2_173,Kka2,kka2_1:2,P00552,1.13773,NO,173,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.407,-3.026,0.619,,0.308,H,A,0.16,-0.13,15.389,15.389,65.53,HBH,-1.70533,0.295029,0.00784999,1.13773 kka2_1:8_G74E,kka2_1:8_74,Kka2,kka2_1:8,P00552,1.13779,NO,74,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.18,-2.749,1.569,,0.621,T,l,0.29,0.2,2.014,,64.39,POH,-1.91667,0.100394,0.00587035,1.13779 kka2_1:8_G74E,kka2_1:8_74,Kka2,kka2_1:8,P00552,1.13779,NO,74,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.18,-2.749,1.569,,0.621,T,l,0.29,0.2,2.014,,64.39,POH,-1.91667,0.100394,0.00587035,1.13779 WW_domain_D170A,WW_domain_170,Yap65,WW_domain,P46937,1.13783,NO,170,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.213,-3.073,1.86,,,,,,,0.399,,15.87,OAH,-1.38,0.153962,0.00123319,1.13783 kka2_1:8_V49M,kka2_1:8_49,Kka2,kka2_1:8,P00552,1.13785,NO,49,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.614,-4.13,2.516,,,E,B,1.48,-0.77,1.31,,64.39,HHB,-1.3,0.100394,0.00615685,1.13785 kka2_1:8_V49M,kka2_1:8_49,Kka2,kka2_1:8,P00552,1.13785,NO,49,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.614,-4.13,2.516,,,E,B,1.48,-0.77,1.31,,64.39,HHB,-1.3,0.100394,0.00615685,1.13785 kka2_1:8_Q252E,kka2_1:8_252,Kka2,kka2_1:8,P00552,1.13801,NO,252,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.63,-1.971,-0.659,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.100394,0.0121001,1.13801 kka2_1:8_Q252E,kka2_1:8_252,Kka2,kka2_1:8,P00552,1.13801,NO,252,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.63,-1.971,-0.659,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.100394,0.0121001,1.13801 kka2_1:4_Q100N,kka2_1:4_100,Kka2,kka2_1:4,P00552,1.13806,NO,100,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.77,-3.216,0.446,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.168804,0.0066405,1.13806 kka2_1:8_R44T,kka2_1:8_44,Kka2,kka2_1:8,P00552,1.13807,NO,44,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.062,-3.662,1.6,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.100394,0.00745043,1.13807 kka2_1:8_R44T,kka2_1:8_44,Kka2,kka2_1:8,P00552,1.13807,NO,44,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.062,-3.662,1.6,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.100394,0.00745043,1.13807 kka2_1:2_A41T,kka2_1:2_41,Kka2,kka2_1:2,P00552,1.13817,NO,41,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.879,-3.68,1.801,,0.184,.,B,0.46,-0.96,24.451,24.451,64.39,PHP,-2.477,0.295029,0.00543332,1.13817 kka2_1:8_V16S,kka2_1:8_16,Kka2,kka2_1:8,P00552,1.1382,NO,16,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-3.087,-2.803,-0.284,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.100394,0.00694011,1.1382 kka2_1:8_V16S,kka2_1:8_16,Kka2,kka2_1:8,P00552,1.1382,NO,16,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-3.087,-2.803,-0.284,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.100394,0.00694011,1.1382 kka2_1:2_A166M,kka2_1:2_166,Kka2,kka2_1:2,P00552,1.13822,NO,166,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.407,-4.784,2.377,,0.534,.,B,0.46,1.03,23.175,23.175,71.59,HHO,-2.421,0.295029,0.00799912,1.13822 kka2_1:4_R173V,kka2_1:4_173,Kka2,kka2_1:4,P00552,1.13823,NO,173,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.407,-3.707,1.3,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.168804,0.00784999,1.13823 beta-lactamase_0_M180K,beta-lactamase_0_180,TEM-1,beta-lactamase_0,P62593,1.13825,NO,180,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-2.795,-3.525,0.73,,0.242,,B,0.55,-0.94,2.892,,77.62,PHO,-1.56433,0.0500837,0.00552048,1.13825 beta-lactamase_0_I93M,beta-lactamase_0_93,TEM-1,beta-lactamase_0,P62593,1.13826,NO,93,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.401,-4.189,2.788,,0.128,E,B,0.48,0.44,1.266,,67.83,BHB,-1.873,0.0500837,0.00527066,1.13826 gb1_T251R,gb1_251,gb1,gb1,P06654,1.13837,NO,251,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.794,-3.57,1.776,,,,,,,3.514,3.514,37.28,HPH,-1.56067,0.177985,0.00232932,1.13837 kka2_1:8_D33E,kka2_1:8_33,Kka2,kka2_1:8,P00552,1.13837,NO,33,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.186,-2.762,0.576,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.100394,0.00633568,1.13837 kka2_1:8_D33E,kka2_1:8_33,Kka2,kka2_1:8,P00552,1.13837,NO,33,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.186,-2.762,0.576,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.100394,0.00633568,1.13837 beta-lactamase_0_M209N,beta-lactamase_0_209,TEM-1,beta-lactamase_0,P62593,1.13842,NO,209,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.442,-4.092,2.65,,,H,A,0.55,-0.97,3.876,,64.69,HHA,-1.52633,0.0500837,0.00625021,1.13842 kka2_1:8_A25Q,kka2_1:8_25,Kka2,kka2_1:8,P00552,1.13848,NO,25,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.496,-2.581,0.085,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.100394,0.00595636,1.13848 kka2_1:8_A25Q,kka2_1:8_25,Kka2,kka2_1:8,P00552,1.13848,NO,25,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.496,-2.581,0.085,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.100394,0.00595636,1.13848 kka2_1:8_P179I,kka2_1:8_179,Kka2,kka2_1:8,P00552,1.13852,NO,179,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.974,-3.795,2.821,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.100394,0.00298346,1.13852 kka2_1:8_P179I,kka2_1:8_179,Kka2,kka2_1:8,P00552,1.13852,NO,179,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.974,-3.795,2.821,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.100394,0.00298346,1.13852 beta-lactamase_0_R189L,beta-lactamase_0_189,TEM-1,beta-lactamase_0,P62593,1.13853,NO,189,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.844,-3.611,1.767,,0.278,H,A,1.2,1.01,12.11,12.11,72.73,HBB,-1.668,0.0500837,0.0050699,1.13853 beta-lactamase_0_I140Q,beta-lactamase_0_140,TEM-1,beta-lactamase_0,P62593,1.13857,NO,140,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.733,-4.321,2.588,,0.128,H,A,0.48,0.41,4.714,,73.08,PHO,-1.48733,0.0500837,0.00597777,1.13857 kka2_1:8_E111A,kka2_1:8_111,Kka2,kka2_1:8,P00552,1.13857,NO,111,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.28,-2.356,0.076,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.100394,0.00746789,1.13857 kka2_1:8_E111A,kka2_1:8_111,Kka2,kka2_1:8,P00552,1.13857,NO,111,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.28,-2.356,0.076,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.100394,0.00746789,1.13857 kka2_1:4_L94T,kka2_1:4_94,Kka2,kka2_1:4,P00552,1.13862,NO,94,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.618,-2.787,1.169,,0.058,E,B,0.55,-0.52,0.858,,56.06,HHO,-1.612,0.168804,0.00520888,1.13862 kka2_1:2_V16D,kka2_1:2_16,Kka2,kka2_1:2,P00552,1.13863,NO,16,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-3.087,-2.706,-0.381,,0.742,T,A,0.44,0.34,1.746,,71.59,HHA,-2.211,0.295029,0.00694011,1.13863 beta-lactamase_0_I140D,beta-lactamase_0_140,TEM-1,beta-lactamase_0,P62593,1.13874,NO,140,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.733,-4.079,2.346,,0.128,H,A,0.48,0.41,4.714,,73.08,PHO,-1.48733,0.0500837,0.00597777,1.13874 kka2_1:2_V242G,kka2_1:2_242,Kka2,kka2_1:2,P00552,1.13874,NO,242,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-2.687,-3.538,0.851,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.295029,0.0102575,1.13874 kka2_1:4_A137Q,kka2_1:4_137,Kka2,kka2_1:4,P00552,1.13875,NO,137,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.156,-4.203,2.047,,0.029,H,A,0.46,0.34,2.227,,63.26,PHB,-2.559,0.168804,0.00515054,1.13875 beta-lactamase_0_E238I,beta-lactamase_0_238,TEM-1,beta-lactamase_0,P62593,1.13879,NO,238,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.0500837,0.00743256,1.13879 beta-lactamase_0_K286M,beta-lactamase_0_286,TEM-1,beta-lactamase_0,P62593,1.13879,NO,286,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.111,,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.0500837,,1.13879 kka2_1:8_A71M,kka2_1:8_71,Kka2,kka2_1:8,P00552,1.1388,NO,71,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.824,-3.582,1.758,,0.553,H,A,0.46,0.08,18.64,18.64,64.39,HHP,-1.74033,0.100394,0.00727707,1.1388 kka2_1:8_A71M,kka2_1:8_71,Kka2,kka2_1:8,P00552,1.1388,NO,71,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.824,-3.582,1.758,,0.553,H,A,0.46,0.08,18.64,18.64,64.39,HHP,-1.74033,0.100394,0.00727707,1.1388 kka2_1:8_G181S,kka2_1:8_181,Kka2,kka2_1:8,P00552,1.13884,NO,181,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-2.698,-2.485,-0.213,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.100394,0.00728319,1.13884 kka2_1:8_G181S,kka2_1:8_181,Kka2,kka2_1:8,P00552,1.13884,NO,181,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-2.698,-2.485,-0.213,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.100394,0.00728319,1.13884 kka2_1:8_A191C,kka2_1:8_191,Kka2,kka2_1:8,P00552,1.13885,NO,191,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.831,-4.548,3.717,,,,b,1.04,-0.94,1.306,,50,AHO,-0.868667,0.100394,0.00338807,1.13885 kka2_1:8_A191C,kka2_1:8_191,Kka2,kka2_1:8,P00552,1.13885,NO,191,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.831,-4.548,3.717,,,,b,1.04,-0.94,1.306,,50,AHO,-0.868667,0.100394,0.00338807,1.13885 kka2_1:2_E142R,kka2_1:2_142,Kka2,kka2_1:2,P00552,1.13895,NO,142,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.221,-2.483,0.262,,0.471,H,A,1.52,0.85,3.693,,65.53,HAB,-2.08033,0.295029,0.00748883,1.13895 gb1_A246R,gb1_246,gb1,gb1,P06654,1.13898,NO,246,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.175,-3.443,2.268,,,,,,,,,,AHH,-1.87033,0.177985,0.00190625,1.13898 kka2_1:8_P179H,kka2_1:8_179,Kka2,kka2_1:8,P00552,1.13898,NO,179,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.974,-4.803,3.829,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.100394,0.00298346,1.13898 kka2_1:8_P179H,kka2_1:8_179,Kka2,kka2_1:8,P00552,1.13898,NO,179,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.974,-4.803,3.829,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.100394,0.00298346,1.13898 kka2_1:8_A108D,kka2_1:8_108,Kka2,kka2_1:8,P00552,1.13908,NO,108,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.061,-2.378,0.317,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.100394,0.00751209,1.13908 kka2_1:8_A108D,kka2_1:8_108,Kka2,kka2_1:8,P00552,1.13908,NO,108,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.061,-2.378,0.317,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.100394,0.00751209,1.13908 kka2_1:8_D157N,kka2_1:8_157,Kka2,kka2_1:8,P00552,1.13912,NO,157,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.993,-2.434,1.441,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.100394,0.0042313,1.13912 kka2_1:8_D157N,kka2_1:8_157,Kka2,kka2_1:8,P00552,1.13912,NO,157,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.993,-2.434,1.441,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.100394,0.0042313,1.13912 kka2_1:8_R147N,kka2_1:8_147,Kka2,kka2_1:8,P00552,1.13914,NO,147,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.123,-2.501,1.378,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.100394,0.00549168,1.13914 kka2_1:8_R147N,kka2_1:8_147,Kka2,kka2_1:8,P00552,1.13914,NO,147,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.123,-2.501,1.378,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.100394,0.00549168,1.13914 kka2_1:4_V113I,kka2_1:4_113,Kka2,kka2_1:4,P00552,1.13919,NO,113,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.233,-1.634,0.401,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.168804,0.00650191,1.13919 kka2_1:8_R253A,kka2_1:8_253,Kka2,kka2_1:8,P00552,1.13932,NO,253,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.356,-2.382,1.026,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.100394,0.0144195,1.13932 kka2_1:8_R253A,kka2_1:8_253,Kka2,kka2_1:8,P00552,1.13932,NO,253,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.356,-2.382,1.026,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.100394,0.0144195,1.13932 beta-lactamase_0_I140T,beta-lactamase_0_140,TEM-1,beta-lactamase_0,P62593,1.13936,NO,140,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.733,-2.748,1.015,,0.128,H,A,0.48,0.41,4.714,,73.08,PHO,-1.48733,0.0500837,0.00597777,1.13936 kka2_1:8_A150V,kka2_1:8_150,Kka2,kka2_1:8,P00552,1.13943,NO,150,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.949,-3.306,2.357,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.100394,0.0045009,1.13943 kka2_1:8_A150V,kka2_1:8_150,Kka2,kka2_1:8,P00552,1.13943,NO,150,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-0.949,-3.306,2.357,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.100394,0.0045009,1.13943 kka2_1:8_G10K,kka2_1:8_10,Kka2,kka2_1:8,P00552,1.13944,NO,10,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.921,-2.49,0.569,,,,,,,1.862,,71.59,HOP,-2.10733,0.100394,0.00289233,1.13944 kka2_1:8_G10K,kka2_1:8_10,Kka2,kka2_1:8,P00552,1.13944,NO,10,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.921,-2.49,0.569,,,,,,,1.862,,71.59,HOP,-2.10733,0.100394,0.00289233,1.13944 kka2_1:1_V46D,kka2_1:1_46,Kka2,kka2_1:1,P00552,1.13946,NO,46,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-2.62,-2.475,-0.145,,0.192,.,B,0.44,-1.12,20.149,20.149,92.05,OHH,-1.88633,0.520039,0.00631301,1.13946 kka2_1:8_W15M,kka2_1:8_15,Kka2,kka2_1:8,P00552,1.13947,NO,15,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-1.392,-4.272,2.88,,0.01,G,A,1.51,0.15,0.827,,52.27,HHH,-2.10533,0.100394,0.00585505,1.13947 kka2_1:8_W15M,kka2_1:8_15,Kka2,kka2_1:8,P00552,1.13947,NO,15,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-1.392,-4.272,2.88,,0.01,G,A,1.51,0.15,0.827,,52.27,HHH,-2.10533,0.100394,0.00585505,1.13947 kka2_1:8_D250L,kka2_1:8_250,Kka2,kka2_1:8,P00552,1.13948,NO,250,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.015,-3.81,2.795,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.100394,0.0177103,1.13948 kka2_1:8_D250L,kka2_1:8_250,Kka2,kka2_1:8,P00552,1.13948,NO,250,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.015,-3.81,2.795,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.100394,0.0177103,1.13948 kka2_1:8_L103R,kka2_1:8_103,Kka2,kka2_1:8,P00552,1.13957,NO,103,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-2.362,-3.979,1.617,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.100394,0.00574792,1.13957 kka2_1:8_L103R,kka2_1:8_103,Kka2,kka2_1:8,P00552,1.13957,NO,103,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-2.362,-3.979,1.617,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.100394,0.00574792,1.13957 kka2_1:8_H8D,kka2_1:8_8,Kka2,kka2_1:8,P00552,1.13959,NO,8,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-2.759,-3.533,0.774,,,,,,,,,71.59,HBH,-2.25467,0.100394,0.00256422,1.13959 kka2_1:8_H8D,kka2_1:8_8,Kka2,kka2_1:8,P00552,1.13959,NO,8,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-2.759,-3.533,0.774,,,,,,,,,71.59,HBH,-2.25467,0.100394,0.00256422,1.13959 kka2_1:8_A108M,kka2_1:8_108,Kka2,kka2_1:8,P00552,1.13964,NO,108,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.061,-4.804,2.743,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.100394,0.00751209,1.13964 kka2_1:8_A108M,kka2_1:8_108,Kka2,kka2_1:8,P00552,1.13964,NO,108,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.061,-4.804,2.743,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.100394,0.00751209,1.13964 beta-lactamase_0_D99H,beta-lactamase_0_99,TEM-1,beta-lactamase_0,P62593,1.13973,NO,99,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.191,-3.065,1.874,,0.402,G,A,0.75,0.36,0.374,,64.69,PAH,-1.794,0.0500837,0.00305446,1.13973 kka2_1:8_Q4W,kka2_1:8_4,Kka2,kka2_1:8,P00552,1.13979,NO,4,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.361,-5.167,2.806,,,,,,,2.026,,71.59,APA,-1.95533,0.100394,0.00239179,1.13979 kka2_1:8_Q4W,kka2_1:8_4,Kka2,kka2_1:8,P00552,1.13979,NO,4,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.361,-5.167,2.806,,,,,,,2.026,,71.59,APA,-1.95533,0.100394,0.00239179,1.13979 kka2_1:4_Q252V,kka2_1:4_252,Kka2,kka2_1:4,P00552,1.13982,NO,252,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.63,-3.102,0.472,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.168804,0.0121001,1.13982 kka2_1:8_L53Q,kka2_1:8_53,Kka2,kka2_1:8,P00552,1.13983,NO,53,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-2.681,-2.601,-0.08,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.100394,0.00671168,1.13983 kka2_1:8_L53Q,kka2_1:8_53,Kka2,kka2_1:8,P00552,1.13983,NO,53,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-2.681,-2.601,-0.08,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.100394,0.00671168,1.13983 kka2_1:8_Q163E,kka2_1:8_163,Kka2,kka2_1:8,P00552,1.13996,NO,163,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.162,-2.572,0.41,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.100394,0.00719507,1.13996 kka2_1:8_Q163E,kka2_1:8_163,Kka2,kka2_1:8,P00552,1.13996,NO,163,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.162,-2.572,0.41,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.100394,0.00719507,1.13996 kka2_1:8_A172S,kka2_1:8_172,Kka2,kka2_1:8,P00552,1.14001,NO,172,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.757,-2.625,0.868,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.100394,0.0079265,1.14001 kka2_1:8_A172S,kka2_1:8_172,Kka2,kka2_1:8,P00552,1.14001,NO,172,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.757,-2.625,0.868,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.100394,0.0079265,1.14001 beta-lactamase_0_G243I,beta-lactamase_0_243,TEM-1,beta-lactamase_0,P62593,1.14009,NO,243,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.532,-3.58,2.048,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.0500837,0.00464034,1.14009 beta-lactamase_0_L100W,beta-lactamase_0_100,TEM-1,beta-lactamase_0,P62593,1.14009,NO,100,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.218,-5.168,3.95,,0.343,,B,0.55,0.13,1.373,,63.29,AHH,-1.23467,0.0500837,0.00413885,1.14009 beta-lactamase_0_T263E,beta-lactamase_0_263,TEM-1,beta-lactamase_0,P62593,1.14017,NO,263,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.031,,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.0500837,0.0110582,1.14017 beta-lactamase_0_H24K,beta-lactamase_0_24,TEM-1,beta-lactamase_0,P62593,1.14027,NO,24,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-2.481,-3.455,0.974,,,,,,,2.708,,93.01,OBO,-2.0035,0.0500837,0.00238894,1.14027 beta-lactamase_0_L196Q,beta-lactamase_0_196,TEM-1,beta-lactamase_0,P62593,1.14034,NO,196,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-2.478,-3.242,0.764,,0.518,S,A,0.55,1.35,6.513,6.513,77.62,AHH,-1.839,0.0500837,0.00512144,1.14034 beta-lactamase_0_F149H,beta-lactamase_0_149,TEM-1,beta-lactamase_0,P62593,1.14037,NO,149,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.299,-4.304,3.005,,0.195,H,A,0.58,0.11,3.518,,63.99,HHH,-1.46067,0.0500837,0.00418462,1.14037 kka2_1:8_V80L,kka2_1:8_80,Kka2,kka2_1:8,P00552,1.14047,NO,80,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.144,-2.831,1.687,,0.358,E,B,1.48,-0.24,2.562,,63.64,HHH,-1.64633,0.100394,0.00488211,1.14047 kka2_1:8_V80L,kka2_1:8_80,Kka2,kka2_1:8,P00552,1.14047,NO,80,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.144,-2.831,1.687,,0.358,E,B,1.48,-0.24,2.562,,63.64,HHH,-1.64633,0.100394,0.00488211,1.14047 PSD95pdz3_P311L,PSD95pdz3_311,PSD95pdz3,PSD95pdz3,P31016,1.14055,NO,311,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.236,-3.265,2.029,5.76649,,,,,14.78,,,,OOB,-1.409,0.0758425,0.0030796,1.14055 WW_domain_P172G,WW_domain_172,Yap65,WW_domain,P46937,1.14056,NO,172,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.035,-3.135,2.1,,,,,,,,,,HOH,-1.233,0.153962,0.000991485,1.14056 PSD95pdz3_I316L,PSD95pdz3_316,PSD95pdz3,PSD95pdz3,P31016,1.1406,NO,316,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.63,-2.14,0.51,5.46166,,,,,19.005,,,,HHB,-1.62733,0.0758425,0.00112762,1.1406 kka2_1:2_Q163R,kka2_1:2_163,Kka2,kka2_1:2,P00552,1.14073,NO,163,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.162,-2.527,0.365,,0.58,T,B,0.64,1.85,3.888,,64.02,BPO,-1.78333,0.295029,0.00719507,1.14073 beta-lactamase_0_Q267G,beta-lactamase_0_267,TEM-1,beta-lactamase_0,P62593,1.14085,NO,267,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.0500837,0.0102128,1.14085 kka2_1:8_T130S,kka2_1:8_130,Kka2,kka2_1:8,P00552,1.1409,NO,130,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.392,-2.025,-0.367,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.100394,0.00804204,1.1409 kka2_1:8_T130S,kka2_1:8_130,Kka2,kka2_1:8,P00552,1.1409,NO,130,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.392,-2.025,-0.367,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.100394,0.00804204,1.1409 kka2_1:8_A110I,kka2_1:8_110,Kka2,kka2_1:8,P00552,1.14105,NO,110,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.064,-3.899,1.835,,0.175,H,A,1.04,-1.19,11.413,11.413,71.59,OHA,-1.91867,0.100394,0.00759851,1.14105 kka2_1:8_A110I,kka2_1:8_110,Kka2,kka2_1:8,P00552,1.14105,NO,110,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.064,-3.899,1.835,,0.175,H,A,1.04,-1.19,11.413,11.413,71.59,OHA,-1.91867,0.100394,0.00759851,1.14105 kka2_1:8_H8Q,kka2_1:8_8,Kka2,kka2_1:8,P00552,1.14106,NO,8,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-2.759,-2.66,-0.099,,,,,,,,,71.59,HBH,-2.25467,0.100394,0.00256422,1.14106 kka2_1:8_H8Q,kka2_1:8_8,Kka2,kka2_1:8,P00552,1.14106,NO,8,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-2.759,-2.66,-0.099,,,,,,,,,71.59,HBH,-2.25467,0.100394,0.00256422,1.14106 beta-lactamase_0_G141F,beta-lactamase_0_141,TEM-1,beta-lactamase_0,P62593,1.14107,NO,141,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.828,-4.352,3.524,,0.575,T,l,0.29,-0.28,0.722,,64.69,HOO,-1.08933,0.0500837,0.0012419,1.14107 beta-lactamase_0_I244L,beta-lactamase_0_244,TEM-1,beta-lactamase_0,P62593,1.14107,NO,244,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.555,-2.697,1.142,,,E,B,0.48,-0.84,1.241,,77.62,OHH,-1.385,0.0500837,0.00605379,1.14107 kka2_1:4_R143I,kka2_1:4_143,Kka2,kka2_1:4,P00552,1.14111,NO,143,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.525,-2.77,0.245,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.168804,0.00662247,1.14111 kka2_1:2_A110D,kka2_1:2_110,Kka2,kka2_1:2,P00552,1.14116,NO,110,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.064,-2.796,0.732,,0.175,H,A,0.46,-1.19,23.237,23.237,71.59,OHA,-1.91867,0.295029,0.00759851,1.14116 kka2_1:4_G55H,kka2_1:4_55,Kka2,kka2_1:4,P00552,1.1412,NO,55,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.625,-2.922,1.297,,0.517,S,b,0.75,1.19,15.753,15.753,63.64,POH,-2.05967,0.168804,0.00667877,1.1412 beta-lactamase_0_I93P,beta-lactamase_0_93,TEM-1,beta-lactamase_0,P62593,1.14123,NO,93,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.401,-2.926,1.525,,0.128,E,B,0.48,0.44,1.266,,67.83,BHB,-1.873,0.0500837,0.00527066,1.14123 kka2_1:8_V198H,kka2_1:8_198,Kka2,kka2_1:8,P00552,1.14124,NO,198,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.719,-4.876,3.157,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.100394,0.00835002,1.14124 kka2_1:8_V198H,kka2_1:8_198,Kka2,kka2_1:8,P00552,1.14124,NO,198,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.719,-4.876,3.157,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.100394,0.00835002,1.14124 kka2_1:8_A229Q,kka2_1:8_229,Kka2,kka2_1:8,P00552,1.14126,NO,229,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.739,-3.175,1.436,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.100394,0.00942138,1.14126 kka2_1:8_A229Q,kka2_1:8_229,Kka2,kka2_1:8,P00552,1.14126,NO,229,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.739,-3.175,1.436,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.100394,0.00942138,1.14126 kka2_1:8_A71W,kka2_1:8_71,Kka2,kka2_1:8,P00552,1.14129,NO,71,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.824,-5.529,3.705,,0.553,H,A,0.46,0.08,18.64,18.64,64.39,HHP,-1.74033,0.100394,0.00727707,1.14129 kka2_1:8_A71W,kka2_1:8_71,Kka2,kka2_1:8,P00552,1.14129,NO,71,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.824,-5.529,3.705,,0.553,H,A,0.46,0.08,18.64,18.64,64.39,HHP,-1.74033,0.100394,0.00727707,1.14129 beta-lactamase_0_I206M,beta-lactamase_0_206,TEM-1,beta-lactamase_0,P62593,1.14135,NO,206,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-2.429,-3.069,0.64,,0.173,H,A,0.48,-0.34,3.411,,77.62,HHA,-1.805,0.0500837,0.00528934,1.14135 beta-lactamase_0_Y44H,beta-lactamase_0_44,TEM-1,beta-lactamase_0,P62593,1.14138,NO,44,Y,H,YH,Hydrophobic,PositiveCharge,5.66,7.59,1.93,83,181,155,-26,193.6,153.2,-40.4,-2.547,-4.769,2.222,,,E,B,0.21,-0.45,1.751,,73.78,OHH,-1.86267,0.0500837,0.00426364,1.14138 kka2_1:2_E231F,kka2_1:2_231,Kka2,kka2_1:2,P00552,1.14139,NO,231,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.002,-4.394,2.392,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.295029,0.00732383,1.14139 kka2_1:8_D157C,kka2_1:8_157,Kka2,kka2_1:8,P00552,1.1414,NO,157,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.993,-5.181,4.188,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.100394,0.0042313,1.1414 kka2_1:8_D157C,kka2_1:8_157,Kka2,kka2_1:8,P00552,1.1414,NO,157,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.993,-5.181,4.188,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.100394,0.0042313,1.1414 kka2_1:8_I196L,kka2_1:8_196,Kka2,kka2_1:8,P00552,1.1414,NO,196,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-2.115,-1.762,-0.353,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.100394,0.0107273,1.1414 kka2_1:8_I196L,kka2_1:8_196,Kka2,kka2_1:8,P00552,1.1414,NO,196,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-2.115,-1.762,-0.353,,,E,B,0.48,-1.41,1.69,,63.64,PHH,-1.55267,0.100394,0.0107273,1.1414 beta-lactamase_0_A132K,beta-lactamase_0_132,TEM-1,beta-lactamase_0,P62593,1.14142,NO,132,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.9,-3.501,2.601,,,H,A,0.46,-0.93,2.249,,64.69,PHH,-1.138,0.0500837,0.000962524,1.14142 kka2_1:8_Q100D,kka2_1:8_100,Kka2,kka2_1:8,P00552,1.14143,NO,100,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.77,-3.173,0.403,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.100394,0.0066405,1.14143 kka2_1:8_Q100D,kka2_1:8_100,Kka2,kka2_1:8,P00552,1.14143,NO,100,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.77,-3.173,0.403,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.100394,0.0066405,1.14143 kka2_1:8_A110V,kka2_1:8_110,Kka2,kka2_1:8,P00552,1.14151,NO,110,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.064,-2.939,0.875,,0.175,H,A,1.04,-1.19,11.413,11.413,71.59,OHA,-1.91867,0.100394,0.00759851,1.14151 kka2_1:8_A110V,kka2_1:8_110,Kka2,kka2_1:8,P00552,1.14151,NO,110,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.064,-2.939,0.875,,0.175,H,A,1.04,-1.19,11.413,11.413,71.59,OHA,-1.91867,0.100394,0.00759851,1.14151 kka2_1:4_T225A,kka2_1:4_225,Kka2,kka2_1:4,P00552,1.14154,NO,225,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.393,-1.787,-0.606,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.168804,0.0113598,1.14154 kka2_1:4_D154G,kka2_1:4_154,Kka2,kka2_1:4,P00552,1.1416,NO,154,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.876,-3.201,2.325,,0.457,,b,0.29,1.48,15.641,15.641,52.65,HAP,-1.52467,0.168804,0.00292633,1.1416 kka2_1:8_V80T,kka2_1:8_80,Kka2,kka2_1:8,P00552,1.1416,NO,80,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.144,-3.381,2.237,,0.358,E,B,1.48,-0.24,2.562,,63.64,HHH,-1.64633,0.100394,0.00488211,1.1416 kka2_1:8_V80T,kka2_1:8_80,Kka2,kka2_1:8,P00552,1.1416,NO,80,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.144,-3.381,2.237,,0.358,E,B,1.48,-0.24,2.562,,63.64,HHH,-1.64633,0.100394,0.00488211,1.1416 beta-lactamase_0_F149A,beta-lactamase_0_149,TEM-1,beta-lactamase_0,P62593,1.14167,NO,149,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.299,-3.341,2.042,,0.195,H,A,0.58,0.11,3.518,,63.99,HHH,-1.46067,0.0500837,0.00418462,1.14167 kka2_1:8_G181A,kka2_1:8_181,Kka2,kka2_1:8,P00552,1.14172,NO,181,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-2.698,-2.631,-0.067,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.100394,0.00728319,1.14172 kka2_1:8_G181A,kka2_1:8_181,Kka2,kka2_1:8,P00552,1.14172,NO,181,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-2.698,-2.631,-0.067,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.100394,0.00728319,1.14172 kka2_1:8_G181E,kka2_1:8_181,Kka2,kka2_1:8,P00552,1.14172,NO,181,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-2.698,-2.628,-0.07,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.100394,0.00728319,1.14172 kka2_1:8_G181E,kka2_1:8_181,Kka2,kka2_1:8,P00552,1.14172,NO,181,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-2.698,-2.628,-0.07,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.100394,0.00728319,1.14172 beta-lactamase_0_E102G,beta-lactamase_0_102,TEM-1,beta-lactamase_0,P62593,1.14174,NO,102,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.118,-2.728,0.61,,0.722,S,B,1.04,1.82,4.773,,73.08,HAH,-1.581,0.0500837,0.00486633,1.14174 kka2_1:1_T125A,kka2_1:1_125,Kka2,kka2_1:1,P00552,1.14176,NO,125,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.622,-1.886,-0.736,,0.791,T,A,0.22,0.33,1.972,,92.05,BPH,-1.56933,0.520039,0.00821755,1.14176 kka2_1:4_A56P,kka2_1:4_56,Kka2,kka2_1:4,P00552,1.1418,NO,56,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.083,-1.768,-0.315,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.168804,0.00717715,1.1418 kka2_1:2_I141C,kka2_1:2_141,Kka2,kka2_1:2,P00552,1.14182,NO,141,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.495,-4.812,3.317,,0.068,H,A,0.48,-0.01,0.819,,92.05,BHA,-1.689,0.295029,0.00744745,1.14182 kka2_1:2_L92M,kka2_1:2_92,Kka2,kka2_1:2,P00552,1.14183,NO,92,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.893,-2.898,2.005,,0.007,E,B,1.59,-0.19,1.447,,63.26,HHH,-0.962,0.295029,0.00307177,1.14183 kka2_1:8_D156H,kka2_1:8_156,Kka2,kka2_1:8,P00552,1.14183,NO,156,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.696,-4.723,3.027,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.100394,0.00926998,1.14183 kka2_1:8_D156H,kka2_1:8_156,Kka2,kka2_1:8,P00552,1.14183,NO,156,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.696,-4.723,3.027,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.100394,0.00926998,1.14183 kka2_1:8_P249M,kka2_1:8_249,Kka2,kka2_1:8,P00552,1.14186,NO,249,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.867,-3.186,1.319,,0.406,.,B,0.52,-0.01,1.699,,92.05,HOA,-1.66867,0.100394,0.011045,1.14186 kka2_1:8_P249M,kka2_1:8_249,Kka2,kka2_1:8,P00552,1.14186,NO,249,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.867,-3.186,1.319,,0.406,.,B,0.52,-0.01,1.699,,92.05,HOA,-1.66867,0.100394,0.011045,1.14186 kka2_1:8_E235T,kka2_1:8_235,Kka2,kka2_1:8,P00552,1.14202,NO,235,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.955,-3.009,1.054,,0.631,H,A,1.52,0.12,,,65.53,OAH,-2.07267,0.100394,0.0102806,1.14202 kka2_1:8_E235T,kka2_1:8_235,Kka2,kka2_1:8,P00552,1.14202,NO,235,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.955,-3.009,1.054,,0.631,H,A,1.52,0.12,,,65.53,OAH,-2.07267,0.100394,0.0102806,1.14202 kka2_1:4_A248D,kka2_1:4_248,Kka2,kka2_1:4,P00552,1.14215,NO,248,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.124,-2.58,0.456,,0.825,S,b,0.46,0.46,,,92.05,HHO,-2.15,0.168804,0.0125484,1.14215 beta-lactamase_F58N,beta-lactamase_58,TEM-1,beta-lactamase,P62593,1.14221,NO,58,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-2.914,-3.795,0.881,5.55634,0.266,E,B,1.33,-0.07,2.467,,77.62,PHB,-2.059,0.221079,0.00523369,1.14221 beta-lactamase_0_A132Y,beta-lactamase_0_132,TEM-1,beta-lactamase_0,P62593,1.14233,NO,132,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.9,-4.186,3.286,,,H,A,0.46,-0.93,2.249,,64.69,PHH,-1.138,0.0500837,0.000962524,1.14233 PSD95pdz3_P311K,PSD95pdz3_311,PSD95pdz3,PSD95pdz3,P31016,1.14239,NO,311,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.236,-3.139,1.903,5.76649,,,,,14.78,,,,OOB,-1.409,0.0758425,0.0030796,1.14239 kka2_1:4_V16L,kka2_1:4_16,Kka2,kka2_1:4,P00552,1.14244,NO,16,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-3.087,-2.643,-0.444,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.168804,0.00694011,1.14244 kka2_1:4_L152F,kka2_1:4_152,Kka2,kka2_1:4,P00552,1.14253,NO,152,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.521,-4.081,2.56,,0.547,,A,1.59,1.36,2.318,,63.64,OHH,-1.162,0.168804,0.00674868,1.14253 beta-lactamase_0_F228T,beta-lactamase_0_228,TEM-1,beta-lactamase_0,P62593,1.14256,NO,228,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-2.342,-2.522,0.18,,0.154,E,B,0.58,-0.42,15.504,15.504,63.29,HHH,-1.53033,0.0500837,0.0046669,1.14256 kka2_1:8_E111V,kka2_1:8_111,Kka2,kka2_1:8,P00552,1.14256,NO,111,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.28,-2.806,0.526,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.100394,0.00746789,1.14256 kka2_1:8_E111V,kka2_1:8_111,Kka2,kka2_1:8,P00552,1.14256,NO,111,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.28,-2.806,0.526,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.100394,0.00746789,1.14256 kka2_1:8_H8E,kka2_1:8_8,Kka2,kka2_1:8,P00552,1.14256,NO,8,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-2.759,-3.378,0.619,,,,,,,,,71.59,HBH,-2.25467,0.100394,0.00256422,1.14256 kka2_1:8_H8E,kka2_1:8_8,Kka2,kka2_1:8,P00552,1.14256,NO,8,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-2.759,-3.378,0.619,,,,,,,,,71.59,HBH,-2.25467,0.100394,0.00256422,1.14256 beta-lactamase_0_P105K,beta-lactamase_0_105,TEM-1,beta-lactamase_0,P62593,1.1426,NO,105,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-0.813,-3.454,2.641,,0.226,T,A,0.52,0.8,3.48,,63.29,POH,-1.01533,0.0500837,0.0011981,1.1426 beta-lactamase_0_V106A,beta-lactamase_0_106,TEM-1,beta-lactamase_0,P62593,1.14264,NO,106,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.218,-3.084,1.866,,0.258,T,A,0.44,0.24,0.952,,72.73,OHP,-1.04933,0.0500837,0.00304168,1.14264 beta-lactamase_0_H94R,beta-lactamase_0_94,TEM-1,beta-lactamase_0,P62593,1.14275,NO,94,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-2.5,-2.531,0.031,,0.776,,B,0.17,1.24,1.176,,77.62,HBH,-1.872,0.0500837,0.00389226,1.14275 kka2_1:2_A247C,kka2_1:2_247,Kka2,kka2_1:2,P00552,1.14275,NO,247,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.459,-5.101,2.642,,1.01,S,A,0.46,0.65,0.828,,92.05,HHH,-2.197,0.295029,0.0102428,1.14275 beta-lactamase_0_S221K,beta-lactamase_0_221,TEM-1,beta-lactamase_0,P62593,1.14281,NO,221,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.754,-2.447,0.693,,0.624,H,A,0.27,-0.2,2.914,,74.48,BPH,-1.59967,0.0500837,0.0046094,1.14281 PSD95pdz3_P311I,PSD95pdz3_311,PSD95pdz3,PSD95pdz3,P31016,1.14285,NO,311,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.236,-3.692,2.456,5.76649,,,,,14.78,,,,OOB,-1.409,0.0758425,0.0030796,1.14285 kka2_1:8_A255K,kka2_1:8_255,Kka2,kka2_1:8,P00552,1.14297,NO,255,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.715,-2.818,1.103,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.100394,0.0126809,1.14297 kka2_1:8_A255K,kka2_1:8_255,Kka2,kka2_1:8,P00552,1.14297,NO,255,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.715,-2.818,1.103,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.100394,0.0126809,1.14297 kka2_1:1_G6C,kka2_1:1_6,Kka2,kka2_1:1,P00552,1.14302,NO,6,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.685,-2.485,0.8,,,,,,,1.292,,71.59,AOH,-1.639,0.520039,0.00204693,1.14302 kka2_1:2_A71G,kka2_1:2_71,Kka2,kka2_1:2,P00552,1.14302,NO,71,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.824,-2.399,0.575,,0.553,H,A,0.46,0.08,9.788,,64.39,HHP,-1.74033,0.295029,0.00727707,1.14302 gb1_A250T,gb1_250,gb1,gb1,P06654,1.14307,NO,250,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.713,-3.197,1.484,,,,,,,3.465,,45.54,HHP,-1.74867,0.177985,0.00332003,1.14307 kka2_1:2_I246E,kka2_1:2_246,Kka2,kka2_1:2,P00552,1.14327,NO,246,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-2.008,-3.889,1.881,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.295029,0.0139479,1.14327 beta-lactamase_0_S283N,beta-lactamase_0_283,TEM-1,beta-lactamase_0,P62593,1.14333,NO,283,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.0500837,0.0429138,1.14333 PSD95pdz3_P311D,PSD95pdz3_311,PSD95pdz3,PSD95pdz3,P31016,1.14333,NO,311,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.236,-3.15,1.914,5.76649,,,,,14.78,,,,OOB,-1.409,0.0758425,0.0030796,1.14333 kka2_1:8_P167W,kka2_1:8_167,Kka2,kka2_1:8,P00552,1.14335,NO,167,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-2.403,-5.529,3.126,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.100394,0.00543203,1.14335 kka2_1:8_P167W,kka2_1:8_167,Kka2,kka2_1:8,P00552,1.14335,NO,167,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-2.403,-5.529,3.126,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.100394,0.00543203,1.14335 kka2_1:8_Q252V,kka2_1:8_252,Kka2,kka2_1:8,P00552,1.14335,NO,252,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.63,-3.102,0.472,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.100394,0.0121001,1.14335 kka2_1:8_Q252V,kka2_1:8_252,Kka2,kka2_1:8,P00552,1.14335,NO,252,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.63,-3.102,0.472,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.100394,0.0121001,1.14335 kka2_1:8_Y218L,kka2_1:8_218,Kka2,kka2_1:8,P00552,1.14336,NO,218,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-1.438,-3.412,1.974,,0.122,H,A,1.25,-0.69,2.923,,56.06,BHP,-1.17533,0.100394,0.0126098,1.14336 kka2_1:8_Y218L,kka2_1:8_218,Kka2,kka2_1:8,P00552,1.14336,NO,218,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-1.438,-3.412,1.974,,0.122,H,A,1.25,-0.69,2.923,,56.06,BHP,-1.17533,0.100394,0.0126098,1.14336 kka2_1:4_A166Y,kka2_1:4_166,Kka2,kka2_1:4,P00552,1.14338,NO,166,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.407,-4.444,2.037,,0.534,.,B,0.46,1.03,,,71.59,HHO,-2.421,0.168804,0.00799912,1.14338 beta-lactamase_0_A211E,beta-lactamase_0_211,TEM-1,beta-lactamase_0,P62593,1.14341,NO,211,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.896,-2.447,0.551,,0.369,T,A,0.46,-0.69,8.527,8.527,77.62,AHA,-1.94633,0.0500837,0.00648183,1.14341 kka2_1:4_A172S,kka2_1:4_172,Kka2,kka2_1:4,P00552,1.14349,NO,172,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.757,-2.625,0.868,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.168804,0.0079265,1.14349 beta-lactamase_0_T138R,beta-lactamase_0_138,TEM-1,beta-lactamase_0,P62593,1.1435,NO,138,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.506,-2.605,0.099,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.0500837,0.00487868,1.1435 kka2_1:4_S204T,kka2_1:4_204,Kka2,kka2_1:4,P00552,1.14365,NO,204,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.353,-1.747,0.394,,0.144,E,A,0.27,-1.2,2.442,,65.53,HPO,-0.953333,0.168804,0.00881794,1.14365 kka2_1:8_V242S,kka2_1:8_242,Kka2,kka2_1:8,P00552,1.14365,NO,242,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-2.687,-3.455,0.768,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.100394,0.0102575,1.14365 kka2_1:8_V242S,kka2_1:8_242,Kka2,kka2_1:8,P00552,1.14365,NO,242,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-2.687,-3.455,0.768,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.100394,0.0102575,1.14365 kka2_1:4_I246N,kka2_1:4_246,Kka2,kka2_1:4,P00552,1.14366,NO,246,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-2.008,-4.146,2.138,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.168804,0.0139479,1.14366 kka2_1:8_P98K,kka2_1:8_98,Kka2,kka2_1:8,P00552,1.14369,NO,98,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.526,-2.937,1.411,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.100394,0.00622754,1.14369 kka2_1:8_P98K,kka2_1:8_98,Kka2,kka2_1:8,P00552,1.14369,NO,98,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.526,-2.937,1.411,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.100394,0.00622754,1.14369 gb1_A250N,gb1_250,gb1,gb1,P06654,1.14373,NO,250,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.713,-3.46,1.747,,,,,,,3.465,,45.54,HHP,-1.74867,0.177985,0.00332003,1.14373 beta-lactamase_0_P181W,beta-lactamase_0_181,TEM-1,beta-lactamase_0,P62593,1.14376,NO,181,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.813,-5.545,4.732,,,H,A,0.52,-1.14,1.357,,61.54,HOH,-1.795,0.0500837,0.000703122,1.14376 kka2_1:4_Q155F,kka2_1:4_155,Kka2,kka2_1:4,P00552,1.14378,NO,155,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.606,-4.366,1.76,,0.525,T,A,0.64,1.49,1.592,,63.64,APA,-1.726,0.168804,0.00641853,1.14378 kka2_1:4_R44E,kka2_1:4_44,Kka2,kka2_1:4,P00552,1.14381,NO,44,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.062,-2.778,0.716,,0.487,S,B,1.2,-0.35,5.71,,71.59,OBO,-1.80767,0.168804,0.00745043,1.14381 kka2_1:2_L260M,kka2_1:2_260,Kka2,kka2_1:2,P00552,1.14384,NO,260,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.741,-3.833,3.092,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.295029,0.0233782,1.14384 beta-lactamase_0_I206Y,beta-lactamase_0_206,TEM-1,beta-lactamase_0,P62593,1.14386,NO,206,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-2.429,-4.278,1.849,,0.173,H,A,0.48,-0.34,3.411,,77.62,HHA,-1.805,0.0500837,0.00528934,1.14386 kka2_1:8_R44Q,kka2_1:8_44,Kka2,kka2_1:8,P00552,1.14395,NO,44,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.062,-2.483,0.421,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.100394,0.00745043,1.14395 kka2_1:8_R44Q,kka2_1:8_44,Kka2,kka2_1:8,P00552,1.14395,NO,44,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.062,-2.483,0.421,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.100394,0.00745043,1.14395 kka2_1:8_A176K,kka2_1:8_176,Kka2,kka2_1:8,P00552,1.14398,NO,176,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.621,-2.698,1.077,,0.806,H,A,0.46,-0.03,18.904,18.904,65.53,BHB,-2.26667,0.100394,0.0083587,1.14398 kka2_1:8_A176K,kka2_1:8_176,Kka2,kka2_1:8,P00552,1.14398,NO,176,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.621,-2.698,1.077,,0.806,H,A,0.46,-0.03,18.904,18.904,65.53,BHB,-2.26667,0.100394,0.0083587,1.14398 kka2_1:8_Q42S,kka2_1:8_42,Kka2,kka2_1:8,P00552,1.14399,NO,42,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.907,-2.69,-0.217,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.100394,0.00679212,1.14399 kka2_1:8_Q42S,kka2_1:8_42,Kka2,kka2_1:8,P00552,1.14399,NO,42,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.907,-2.69,-0.217,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.100394,0.00679212,1.14399 beta-lactamase_0_I261D,beta-lactamase_0_261,TEM-1,beta-lactamase_0,P62593,1.14402,NO,261,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.0500837,0.0123091,1.14402 kka2_1:4_P249S,kka2_1:4_249,Kka2,kka2_1:4,P00552,1.14403,NO,249,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.867,-3.595,1.728,,0.406,.,B,0.52,-0.01,,,92.05,HOA,-1.66867,0.168804,0.011045,1.14403 kka2_1:8_T73S,kka2_1:8_73,Kka2,kka2_1:8,P00552,1.14403,NO,73,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.51,-2.503,-0.007,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.100394,0.00628605,1.14403 kka2_1:8_T73S,kka2_1:8_73,Kka2,kka2_1:8,P00552,1.14403,NO,73,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.51,-2.503,-0.007,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.100394,0.00628605,1.14403 beta-lactamase_0_H94E,beta-lactamase_0_94,TEM-1,beta-lactamase_0,P62593,1.14407,NO,94,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-2.5,-2.415,-0.085,,0.776,,B,0.17,1.24,1.176,,77.62,HBH,-1.872,0.0500837,0.00389226,1.14407 beta-lactamase_0_G236P,beta-lactamase_0_236,TEM-1,beta-lactamase_0,P62593,1.14409,NO,236,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.784,-3.879,3.095,,0.241,,b,0.29,-0.59,3.506,,64.69,HOO,-1.025,0.0500837,0.00162372,1.14409 kka2_1:8_Q136I,kka2_1:8_136,Kka2,kka2_1:8,P00552,1.14409,NO,136,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-3.021,-4.106,1.085,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.100394,0.00624149,1.14409 kka2_1:8_Q136I,kka2_1:8_136,Kka2,kka2_1:8,P00552,1.14409,NO,136,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-3.021,-4.106,1.085,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.100394,0.00624149,1.14409 kka2_1:8_L241I,kka2_1:8_241,Kka2,kka2_1:8,P00552,1.1441,NO,241,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.158,-3.164,2.006,,0.08,H,A,1.59,-0.82,1.136,,63.26,HHH,-1.58533,0.100394,0.0117299,1.1441 kka2_1:8_L241I,kka2_1:8_241,Kka2,kka2_1:8,P00552,1.1441,NO,241,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.158,-3.164,2.006,,0.08,H,A,1.59,-0.82,1.136,,63.26,HHH,-1.58533,0.100394,0.0117299,1.1441 beta-lactamase_0_R239L,beta-lactamase_0_239,TEM-1,beta-lactamase_0,P62593,1.14414,NO,239,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.0500837,0.00213852,1.14414 kka2_1:8_A248T,kka2_1:8_248,Kka2,kka2_1:8,P00552,1.14419,NO,248,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.124,-3.092,0.968,,0.825,S,b,1.04,0.46,11.329,11.329,92.05,HHO,-2.15,0.100394,0.0125484,1.14419 kka2_1:8_A248T,kka2_1:8_248,Kka2,kka2_1:8,P00552,1.14419,NO,248,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.124,-3.092,0.968,,0.825,S,b,1.04,0.46,11.329,11.329,92.05,HHO,-2.15,0.100394,0.0125484,1.14419 kka2_1:8_T28I,kka2_1:8_28,Kka2,kka2_1:8,P00552,1.14425,NO,28,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.883,-3.847,1.964,,0.353,S,B,0.22,2.02,18.114,18.114,63.64,PPH,-1.74467,0.100394,0.00743084,1.14425 kka2_1:8_T28I,kka2_1:8_28,Kka2,kka2_1:8,P00552,1.14425,NO,28,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.883,-3.847,1.964,,0.353,S,B,0.22,2.02,18.114,18.114,63.64,PPH,-1.74467,0.100394,0.00743084,1.14425 kka2_1:8_R143D,kka2_1:8_143,Kka2,kka2_1:8,P00552,1.14426,NO,143,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.525,-2.588,0.063,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.100394,0.00662247,1.14426 kka2_1:8_R143D,kka2_1:8_143,Kka2,kka2_1:8,P00552,1.14426,NO,143,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.525,-2.588,0.063,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.100394,0.00662247,1.14426 kka2_1:2_G10R,kka2_1:2_10,Kka2,kka2_1:2,P00552,1.14428,NO,10,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.921,-2.648,0.727,,,,,,,2.192,,71.59,HOP,-2.10733,0.295029,0.00289233,1.14428 kka2_1:2_A71N,kka2_1:2_71,Kka2,kka2_1:2,P00552,1.14434,NO,71,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.824,-2.731,0.907,,0.553,H,A,0.46,0.08,9.788,,64.39,HHP,-1.74033,0.295029,0.00727707,1.14434 kka2_1:4_R122T,kka2_1:4_122,Kka2,kka2_1:4,P00552,1.14437,NO,122,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.175,-2.452,0.277,,0.487,H,A,0.16,0.26,16.436,16.436,71.59,BBH,-1.53833,0.168804,0.00736512,1.14437 kka2_1:4_R18T,kka2_1:4_18,Kka2,kka2_1:4,P00552,1.14438,NO,18,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.055,-2.928,0.873,,0.474,T,A,1.2,0.54,8.405,8.405,71.59,ABH,-1.821,0.168804,0.00724065,1.14438 kka2_1:2_Q155M,kka2_1:2_155,Kka2,kka2_1:2,P00552,1.14442,NO,155,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.606,-4.733,2.127,,0.525,T,A,0.64,1.49,1.592,,63.64,APA,-1.726,0.295029,0.00641853,1.14442 kka2_1:8_E231V,kka2_1:8_231,Kka2,kka2_1:8,P00552,1.1445,NO,231,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.002,-2.912,0.91,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.100394,0.00732383,1.1445 kka2_1:8_E231V,kka2_1:8_231,Kka2,kka2_1:8,P00552,1.1445,NO,231,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.002,-2.912,0.91,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.100394,0.00732383,1.1445 kka2_1:8_P98A,kka2_1:8_98,Kka2,kka2_1:8,P00552,1.14462,NO,98,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.526,-2.324,0.798,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.100394,0.00622754,1.14462 kka2_1:8_P98A,kka2_1:8_98,Kka2,kka2_1:8,P00552,1.14462,NO,98,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.526,-2.324,0.798,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.100394,0.00622754,1.14462 kka2_1:2_A172Y,kka2_1:2_172,Kka2,kka2_1:2,P00552,1.14471,NO,172,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.757,-4.449,2.692,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.295029,0.0079265,1.14471 kka2_1:2_D180H,kka2_1:2_180,Kka2,kka2_1:2,P00552,1.14483,NO,180,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.416,-3.405,0.989,,1.03,S,a,0.75,1.5,1.27,,71.59,OAO,-2.02933,0.295029,0.00756412,1.14483 beta-lactamase_0_D99E,beta-lactamase_0_99,TEM-1,beta-lactamase_0,P62593,1.14487,NO,99,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.191,-2.122,0.931,,0.402,G,A,0.75,0.36,0.374,,64.69,PAH,-1.794,0.0500837,0.00305446,1.14487 kka2_1:8_Q136C,kka2_1:8_136,Kka2,kka2_1:8,P00552,1.14488,NO,136,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-3.021,-3.362,0.341,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.100394,0.00624149,1.14488 kka2_1:8_Q136C,kka2_1:8_136,Kka2,kka2_1:8,P00552,1.14488,NO,136,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-3.021,-3.362,0.341,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.100394,0.00624149,1.14488 kka2_1:4_E230M,kka2_1:4_230,Kka2,kka2_1:4,P00552,1.1449,NO,230,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.672,-4.815,2.143,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.168804,0.00920051,1.1449 kka2_1:4_Q252P,kka2_1:4_252,Kka2,kka2_1:4,P00552,1.14493,NO,252,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.63,-3.996,1.366,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.168804,0.0121001,1.14493 beta-lactamase_0_E279D,beta-lactamase_0_279,TEM-1,beta-lactamase_0,P62593,1.14494,NO,279,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.0500837,0.0192826,1.14494 kka2_1:8_R202H,kka2_1:8_202,Kka2,kka2_1:8,P00552,1.14495,NO,202,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.761,-2.934,1.173,,0.607,E,B,1.2,0.48,1.409,,52.27,OBH,-1.41067,0.100394,0.00696498,1.14495 kka2_1:8_R202H,kka2_1:8_202,Kka2,kka2_1:8,P00552,1.14495,NO,202,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.761,-2.934,1.173,,0.607,E,B,1.2,0.48,1.409,,52.27,OBH,-1.41067,0.100394,0.00696498,1.14495 kka2_1:2_E17Q,kka2_1:2_17,Kka2,kka2_1:2,P00552,1.14497,NO,17,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.154,-2.533,0.379,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.295029,0.00688738,1.14497 gb1_A250G,gb1_250,gb1,gb1,P06654,1.14498,NO,250,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.713,-3.031,1.318,,,,,,,3.465,,45.54,HHP,-1.74867,0.177985,0.00332003,1.14498 kka2_1:4_E235R,kka2_1:4_235,Kka2,kka2_1:4,P00552,1.145,NO,235,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.955,-2.75,0.795,,0.631,H,A,1.04,0.12,23.175,23.175,65.53,OAH,-2.07267,0.168804,0.0102806,1.145 kka2_1:8_E160K,kka2_1:8_160,Kka2,kka2_1:8,P00552,1.14503,NO,160,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.683,-2.805,1.122,,0.989,G,A,1.04,2.28,2.164,,71.59,AAA,-1.36133,0.100394,0.00935762,1.14503 kka2_1:8_E160K,kka2_1:8_160,Kka2,kka2_1:8,P00552,1.14503,NO,160,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.683,-2.805,1.122,,0.989,G,A,1.04,2.28,2.164,,71.59,AAA,-1.36133,0.100394,0.00935762,1.14503 PSD95pdz3_I314F,PSD95pdz3_314,PSD95pdz3,PSD95pdz3,P31016,1.1451,NO,314,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.628,-3.478,1.85,5.39919,,,,,15.7775,0.397,,81.35,BHH,-1.61167,0.0758425,0.0012606,1.1451 beta-lactamase_0_M67A,beta-lactamase_0_67,TEM-1,beta-lactamase_0,P62593,1.14515,NO,67,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-2.231,-2.183,-0.048,,0.006,G,P,0.55,-0.81,24.165,24.165,65.03,HHP,-1.502,0.0500837,0.00409753,1.14515 kka2_1:8_A79C,kka2_1:8_79,Kka2,kka2_1:8,P00552,1.14515,NO,79,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.368,-5.212,2.844,,0.563,.,B,0.46,-0.43,,,71.59,HHH,-1.752,0.100394,0.00664821,1.14515 kka2_1:8_A79C,kka2_1:8_79,Kka2,kka2_1:8,P00552,1.14515,NO,79,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.368,-5.212,2.844,,0.563,.,B,0.46,-0.43,,,71.59,HHH,-1.752,0.100394,0.00664821,1.14515 kka2_1:8_A9Q,kka2_1:8_9,Kka2,kka2_1:8,P00552,1.1452,NO,9,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.079,-3.919,1.84,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.100394,0.00273264,1.1452 kka2_1:8_A9Q,kka2_1:8_9,Kka2,kka2_1:8,P00552,1.1452,NO,9,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.079,-3.919,1.84,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.100394,0.00273264,1.1452 kka2_1:2_A237V,kka2_1:2_237,Kka2,kka2_1:2,P00552,1.14533,NO,237,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.12,-1.303,-0.817,,0.068,H,A,0.46,-0.71,2.369,,92.05,HHA,-2.10433,0.295029,0.012257,1.14533 kka2_1:2_A13S,kka2_1:2_13,Kka2,kka2_1:2,P00552,1.14537,NO,13,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.248,-2.545,0.297,,0.689,G,A,0.46,0.99,,,92.05,OHH,-1.646,0.295029,0.00784241,1.14537 kka2_1:4_A248G,kka2_1:4_248,Kka2,kka2_1:4,P00552,1.14537,NO,248,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.124,-2.636,0.512,,0.825,S,b,0.46,0.46,,,92.05,HHO,-2.15,0.168804,0.0125484,1.14537 beta-lactamase_0_S233T,beta-lactamase_0_233,TEM-1,beta-lactamase_0,P62593,1.14556,NO,233,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.886,-1.229,-0.657,,0.016,E,B,0.27,-1.01,3.579,,77.62,BPO,-1.17267,0.0500837,0.00311415,1.14556 kka2_1:2_A41M,kka2_1:2_41,Kka2,kka2_1:2,P00552,1.14562,NO,41,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.879,-3.613,1.734,,0.184,.,B,0.46,-0.96,24.451,24.451,64.39,PHP,-2.477,0.295029,0.00543332,1.14562 beta-lactamase_0_H94L,beta-lactamase_0_94,TEM-1,beta-lactamase_0,P62593,1.14566,NO,94,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-2.5,-3.441,0.941,,0.776,,B,0.17,1.24,1.176,,77.62,HBH,-1.872,0.0500837,0.00389226,1.14566 kka2_1:2_L165M,kka2_1:2_165,Kka2,kka2_1:2,P00552,1.14567,NO,165,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-2.453,-2.818,0.365,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.295029,0.00801161,1.14567 kka2_1:2_E199N,kka2_1:2_199,Kka2,kka2_1:2,P00552,1.14569,NO,199,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.234,-3.807,1.573,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.295029,0.00854122,1.14569 kka2_1:2_K175E,kka2_1:2_175,Kka2,kka2_1:2,P00552,1.14569,NO,175,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-2.897,-2.454,-0.443,,0.579,H,A,1.3,0.51,15.629,15.629,71.59,HBH,-1.82333,0.295029,0.00693093,1.14569 beta-lactamase_0_S241I,beta-lactamase_0_241,TEM-1,beta-lactamase_0,P62593,1.14573,NO,241,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.0500837,0.00452736,1.14573 kka2_1:8_A35D,kka2_1:8_35,Kka2,kka2_1:8,P00552,1.14583,NO,35,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.127,-2.127,0,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.100394,0.00630016,1.14583 kka2_1:8_A35D,kka2_1:8_35,Kka2,kka2_1:8,P00552,1.14583,NO,35,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.127,-2.127,0,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.100394,0.00630016,1.14583 kka2_1:2_A168P,kka2_1:2_168,Kka2,kka2_1:2,P00552,1.14602,NO,168,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.989,-3.241,1.252,,0.67,H,A,0.46,0.15,25.546,25.546,64.39,OHA,-2.12933,0.295029,0.00806773,1.14602 kka2_1:8_D52E,kka2_1:8_52,Kka2,kka2_1:8,P00552,1.14604,NO,52,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.271,-0.829,-1.442,,0.22,E,B,0.75,0.8,5.447,,71.59,PAH,-2.38367,0.100394,0.00175694,1.14604 kka2_1:8_D52E,kka2_1:8_52,Kka2,kka2_1:8,P00552,1.14604,NO,52,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.271,-0.829,-1.442,,0.22,E,B,0.75,0.8,5.447,,71.59,PAH,-2.38367,0.100394,0.00175694,1.14604 kka2_1:4_P179L,kka2_1:4_179,Kka2,kka2_1:4,P00552,1.14609,NO,179,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.974,-2.273,1.299,,0.113,,B,0.52,0.69,10.913,10.913,56.06,HOA,-2.19867,0.168804,0.00298346,1.14609 beta-lactamase_0_H94D,beta-lactamase_0_94,TEM-1,beta-lactamase_0,P62593,1.14611,NO,94,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-2.5,-3,0.5,,0.776,,B,0.17,1.24,1.176,,77.62,HBH,-1.872,0.0500837,0.00389226,1.14611 kka2_1:8_R253M,kka2_1:8_253,Kka2,kka2_1:8,P00552,1.14621,NO,253,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.356,-4.619,3.263,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.100394,0.0144195,1.14621 kka2_1:8_R253M,kka2_1:8_253,Kka2,kka2_1:8,P00552,1.14621,NO,253,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.356,-4.619,3.263,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.100394,0.0144195,1.14621 kka2_1:8_I246L,kka2_1:8_246,Kka2,kka2_1:8,P00552,1.14622,NO,246,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-2.008,-2.197,0.189,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.100394,0.0139479,1.14622 kka2_1:8_I246L,kka2_1:8_246,Kka2,kka2_1:8,P00552,1.14622,NO,246,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-2.008,-2.197,0.189,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.100394,0.0139479,1.14622 kka2_1:2_G10K,kka2_1:2_10,Kka2,kka2_1:2,P00552,1.14624,NO,10,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.921,-2.49,0.569,,,,,,,2.192,,71.59,HOP,-2.10733,0.295029,0.00289233,1.14624 kka2_1:4_E149N,kka2_1:4_149,Kka2,kka2_1:4,P00552,1.14625,NO,149,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.994,-2.918,0.924,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.168804,0.00803343,1.14625 kka2_1:4_A215G,kka2_1:4_215,Kka2,kka2_1:4,P00552,1.14628,NO,215,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.968,-3.05,2.082,,0.039,E,B,0.46,-0.59,0.754,,50.38,HHA,-1.00467,0.168804,0.00529129,1.14628 beta-lactamase_0_T112K,beta-lactamase_0_112,TEM-1,beta-lactamase_0,P62593,1.1463,NO,112,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.186,-2.704,0.518,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.0500837,0.00531334,1.1463 kka2_1:4_A108C,kka2_1:4_108,Kka2,kka2_1:4,P00552,1.14632,NO,108,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.061,-5.089,3.028,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.168804,0.00751209,1.14632 kka2_1:8_L152T,kka2_1:8_152,Kka2,kka2_1:8,P00552,1.14633,NO,152,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.521,-2.936,1.415,,0.547,.,A,0.55,1.36,1.442,,63.64,OHH,-1.162,0.100394,0.00674868,1.14633 kka2_1:8_L152T,kka2_1:8_152,Kka2,kka2_1:8,P00552,1.14633,NO,152,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.521,-2.936,1.415,,0.547,.,A,0.55,1.36,1.442,,63.64,OHH,-1.162,0.100394,0.00674868,1.14633 kka2_1:8_A172I,kka2_1:8_172,Kka2,kka2_1:8,P00552,1.14636,NO,172,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.757,-3.215,1.458,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.100394,0.0079265,1.14636 kka2_1:8_A172I,kka2_1:8_172,Kka2,kka2_1:8,P00552,1.14636,NO,172,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.757,-3.215,1.458,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.100394,0.0079265,1.14636 PSD95pdz3_V315R,PSD95pdz3_315,PSD95pdz3,PSD95pdz3,P31016,1.14638,NO,315,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.625,-3.928,2.303,5.52024,,,,,18.4557,4.054,,81.35,HHH,-1.62767,0.0758425,0.00153536,1.14638 kka2_1:2_G181Q,kka2_1:2_181,Kka2,kka2_1:2,P00552,1.14641,NO,181,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-2.698,-2.961,0.263,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.295029,0.00728319,1.14641 beta-lactamase_0_S233E,beta-lactamase_0_233,TEM-1,beta-lactamase_0,P62593,1.14644,NO,233,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.886,-3.479,1.593,,0.016,E,B,0.27,-1.01,3.579,,77.62,BPO,-1.17267,0.0500837,0.00311415,1.14644 kka2_1:4_S40V,kka2_1:4_40,Kka2,kka2_1:4,P00552,1.14651,NO,40,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.645,-3.735,1.09,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.168804,0.00693477,1.14651 PSD95pdz3_H317R,PSD95pdz3_317,PSD95pdz3,PSD95pdz3,P31016,1.14653,NO,317,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-1.627,-3.165,1.538,6.19713,,,,,25.885,,,,HBB,-1.613,0.0758425,0.00111619,1.14653 kka2_1:2_E149W,kka2_1:2_149,Kka2,kka2_1:2,P00552,1.14665,NO,149,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.994,-5.569,3.575,,0.674,H,A,1.04,1.63,15.361,15.361,71.59,HAH,-1.59667,0.295029,0.00803343,1.14665 kka2_1:8_P45Q,kka2_1:8_45,Kka2,kka2_1:8,P00552,1.14669,NO,45,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.774,-2.806,1.032,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.100394,0.00590481,1.14669 kka2_1:8_P45Q,kka2_1:8_45,Kka2,kka2_1:8,P00552,1.14669,NO,45,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.774,-2.806,1.032,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.100394,0.00590481,1.14669 kka2_1:2_A248D,kka2_1:2_248,Kka2,kka2_1:2,P00552,1.14682,NO,248,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.124,-2.58,0.456,,0.825,S,b,0.46,0.46,,,92.05,HHO,-2.15,0.295029,0.0125484,1.14682 kka2_1:2_L7I,kka2_1:2_7,Kka2,kka2_1:2,P00552,1.14686,NO,7,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.926,-3.353,1.427,,,,,,,3.012,,71.59,OHB,-2.12333,0.295029,0.00269456,1.14686 beta-lactamase_0_L49D,beta-lactamase_0_49,TEM-1,beta-lactamase_0,P62593,1.1469,NO,49,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.897,-3.778,1.881,,0.131,T,A,0.55,0.04,13.838,13.838,64.69,AHP,-1.99233,0.0500837,0.00401477,1.1469 kka2_1:4_E161I,kka2_1:4_161,Kka2,kka2_1:4,P00552,1.1469,NO,161,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.581,-3.91,2.329,,0.829,G,A,1.52,2.24,1.612,,92.05,AAB,-1.861,0.168804,0.00760103,1.1469 kka2_1:2_A129M,kka2_1:2_129,Kka2,kka2_1:2,P00552,1.14695,NO,129,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.656,-4.824,3.168,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.295029,0.00726862,1.14695 kka2_1:8_P167M,kka2_1:8_167,Kka2,kka2_1:8,P00552,1.14697,NO,167,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-2.403,-4.574,2.171,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.100394,0.00543203,1.14697 kka2_1:8_P167M,kka2_1:8_167,Kka2,kka2_1:8,P00552,1.14697,NO,167,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-2.403,-4.574,2.171,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.100394,0.00543203,1.14697 WW_domain_R187I,WW_domain_187,Yap65,WW_domain,P46937,1.14697,NO,187,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.402,-3.85,2.448,5.05189,,,,,,3.431,,78.57,PBH,-1.362,0.153962,0.00171149,1.14697 beta-lactamase_0_T112F,beta-lactamase_0_112,TEM-1,beta-lactamase_0,P62593,1.14701,NO,112,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.186,-4.382,2.196,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.0500837,0.00531334,1.14701 kka2_1:4_A168F,kka2_1:4_168,Kka2,kka2_1:4,P00552,1.14702,NO,168,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.989,-3.458,1.469,,0.67,H,A,0.46,0.15,,,64.39,OHA,-2.12933,0.168804,0.00806773,1.14702 kka2_1:4_H8I,kka2_1:4_8,Kka2,kka2_1:4,P00552,1.14712,NO,8,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-2.759,-2.602,-0.157,,,,,,,,,71.59,HBH,-2.25467,0.168804,0.00256422,1.14712 kka2_1:4_Q136T,kka2_1:4_136,Kka2,kka2_1:4,P00552,1.14712,NO,136,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-3.021,-2.627,-0.394,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.168804,0.00624149,1.14712 kka2_1:4_G6C,kka2_1:4_6,Kka2,kka2_1:4,P00552,1.14717,NO,6,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.685,-2.485,0.8,,,,,,,,,71.59,AOH,-1.639,0.168804,0.00204693,1.14717 kka2_1:4_A176F,kka2_1:4_176,Kka2,kka2_1:4,P00552,1.1472,NO,176,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.621,-4.399,2.778,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.168804,0.0083587,1.1472 kka2_1:8_P179V,kka2_1:8_179,Kka2,kka2_1:8,P00552,1.14732,NO,179,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.974,-3.463,2.489,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.100394,0.00298346,1.14732 kka2_1:8_P179V,kka2_1:8_179,Kka2,kka2_1:8,P00552,1.14732,NO,179,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.974,-3.463,2.489,,0.113,.,B,0.52,0.69,2.431,,56.06,HOA,-2.19867,0.100394,0.00298346,1.14732 beta-lactamase_0_Y44F,beta-lactamase_0_44,TEM-1,beta-lactamase_0,P62593,1.14734,NO,44,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-2.547,-2.714,0.167,,,E,B,0.21,-0.45,1.751,,73.78,OHH,-1.86267,0.0500837,0.00426364,1.14734 kka2_1:4_P249V,kka2_1:4_249,Kka2,kka2_1:4,P00552,1.14738,NO,249,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.867,-2.403,0.536,,0.406,.,B,0.52,-0.01,,,92.05,HOA,-1.66867,0.168804,0.011045,1.14738 beta-lactamase_0_Q204I,beta-lactamase_0_204,TEM-1,beta-lactamase_0,P62593,1.14756,NO,204,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-1.382,-3.968,2.586,,0.204,H,A,0.64,0.09,2.646,,66.08,PPH,-1.49067,0.0500837,0.00364106,1.14756 PSD95pdz3_H317L,PSD95pdz3_317,PSD95pdz3,PSD95pdz3,P31016,1.14758,NO,317,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-1.627,-3.265,1.638,6.19713,,,,,25.885,,,,HBB,-1.613,0.0758425,0.00111619,1.14758 beta-lactamase_0_I206L,beta-lactamase_0_206,TEM-1,beta-lactamase_0,P62593,1.1476,NO,206,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-2.429,-2.261,-0.168,,0.173,H,A,0.48,-0.34,3.411,,77.62,HHA,-1.805,0.0500837,0.00528934,1.1476 kka2_1:4_K138I,kka2_1:4_138,Kka2,kka2_1:4,P00552,1.14761,NO,138,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-2.5,-3.288,0.788,,0.594,H,A,1.3,0.98,21.267,21.267,71.59,HBB,-2.48833,0.168804,0.00628542,1.14761 kka2_1:2_A35S,kka2_1:2_35,Kka2,kka2_1:2,P00552,1.14778,NO,35,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.127,-2.197,0.07,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.295029,0.00630016,1.14778 beta-lactamase_0_Y44M,beta-lactamase_0_44,TEM-1,beta-lactamase_0,P62593,1.14779,NO,44,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-2.547,-2.521,-0.026,,,E,B,0.21,-0.45,1.751,,73.78,OHH,-1.86267,0.0500837,0.00426364,1.14779 kka2_1:8_F37H,kka2_1:8_37,Kka2,kka2_1:8,P00552,1.14779,NO,37,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.427,-2.73,1.303,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.100394,0.00586193,1.14779 kka2_1:8_F37H,kka2_1:8_37,Kka2,kka2_1:8,P00552,1.14779,NO,37,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.427,-2.73,1.303,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.100394,0.00586193,1.14779 kka2_1:2_R122Q,kka2_1:2_122,Kka2,kka2_1:2,P00552,1.14781,NO,122,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.175,-2.893,0.718,,0.487,H,A,1.2,0.26,16.436,16.436,71.59,BBH,-1.53833,0.295029,0.00736512,1.14781 kka2_1:2_V153L,kka2_1:2_153,Kka2,kka2_1:2,P00552,1.14783,NO,153,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.092,-2.743,1.651,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.295029,0.00501119,1.14783 beta-lactamase_0_N98K,beta-lactamase_0_98,TEM-1,beta-lactamase_0,P62593,1.14785,NO,98,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-2.973,-2.653,-0.32,,0.963,G,A,0.61,1.35,14.853,14.853,77.62,PPA,-2.07867,0.0500837,0.00505389,1.14785 beta-lactamase_0_T264Y,beta-lactamase_0_264,TEM-1,beta-lactamase_0,P62593,1.14788,NO,264,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.985,,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.0500837,0.0119399,1.14788 kka2_1:2_R173K,kka2_1:2_173,Kka2,kka2_1:2,P00552,1.14788,NO,173,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.407,-2.916,0.509,,0.308,H,A,0.16,-0.13,15.389,15.389,65.53,HBH,-1.70533,0.295029,0.00784999,1.14788 kka2_1:8_Q42H,kka2_1:8_42,Kka2,kka2_1:8,P00552,1.14789,NO,42,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.907,-3.3,0.393,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.100394,0.00679212,1.14789 kka2_1:8_Q42H,kka2_1:8_42,Kka2,kka2_1:8,P00552,1.14789,NO,42,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.907,-3.3,0.393,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.100394,0.00679212,1.14789 beta-lactamase_0_R242W,beta-lactamase_0_242,TEM-1,beta-lactamase_0,P62593,1.14792,NO,242,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.0500837,0.00452879,1.14792 kka2_1:8_F37M,kka2_1:8_37,Kka2,kka2_1:8,P00552,1.14793,NO,37,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.427,-4.497,3.07,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.100394,0.00586193,1.14793 kka2_1:8_F37M,kka2_1:8_37,Kka2,kka2_1:8,P00552,1.14793,NO,37,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.427,-4.497,3.07,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.100394,0.00586193,1.14793 kka2_1:8_Q136S,kka2_1:8_136,Kka2,kka2_1:8,P00552,1.14799,NO,136,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-3.021,-2.294,-0.727,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.100394,0.00624149,1.14799 kka2_1:8_Q136S,kka2_1:8_136,Kka2,kka2_1:8,P00552,1.14799,NO,136,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-3.021,-2.294,-0.727,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.100394,0.00624149,1.14799 kka2_1:2_Q155P,kka2_1:2_155,Kka2,kka2_1:2,P00552,1.14807,NO,155,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.606,-3.826,1.22,,0.525,T,A,0.64,1.49,1.592,,63.64,APA,-1.726,0.295029,0.00641853,1.14807 beta-lactamase_0_R242M,beta-lactamase_0_242,TEM-1,beta-lactamase_0,P62593,1.14808,NO,242,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.0500837,0.00452879,1.14808 kka2_1:8_D23T,kka2_1:8_23,Kka2,kka2_1:8,P00552,1.14808,NO,23,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.459,-3.106,0.647,,0.695,E,B,0.75,-0.65,,,65.53,HAH,-1.94033,0.100394,0.007195,1.14808 kka2_1:8_D23T,kka2_1:8_23,Kka2,kka2_1:8,P00552,1.14808,NO,23,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.459,-3.106,0.647,,0.695,E,B,0.75,-0.65,,,65.53,HAH,-1.94033,0.100394,0.007195,1.14808 kka2_1:8_D101S,kka2_1:8_101,Kka2,kka2_1:8,P00552,1.14809,NO,101,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.028,-3.266,2.238,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.100394,0.00423361,1.14809 kka2_1:8_D101S,kka2_1:8_101,Kka2,kka2_1:8,P00552,1.14809,NO,101,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.028,-3.266,2.238,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.100394,0.00423361,1.14809 kka2_1:2_Q100V,kka2_1:2_100,Kka2,kka2_1:2,P00552,1.14814,NO,100,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.77,-2.771,0.001,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.295029,0.0066405,1.14814 kka2_1:4_T28A,kka2_1:4_28,Kka2,kka2_1:4,P00552,1.14819,NO,28,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.883,-2.105,0.222,,0.353,S,B,0.82,2.02,4.415,,63.64,PPH,-1.74467,0.168804,0.00743084,1.14819 kka2_1:2_E86H,kka2_1:2_86,Kka2,kka2_1:2,P00552,1.14833,NO,86,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.86,-2.283,0.423,,0.369,.,B,1.04,1.92,3.573,,63.26,PAH,-1.98067,0.295029,0.00642858,1.14833 beta-lactamase_0_D212C,beta-lactamase_0_212,TEM-1,beta-lactamase_0,P62593,1.14839,NO,212,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.624,-5.061,3.437,,0.037,,b,0.75,-0.58,3.34,,74.48,HAB,-1.77667,0.0500837,0.00644302,1.14839 kka2_1:8_D134A,kka2_1:8_134,Kka2,kka2_1:8,P00552,1.14843,NO,134,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.969,-3.306,2.337,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.100394,0.00270812,1.14843 kka2_1:8_D134A,kka2_1:8_134,Kka2,kka2_1:8,P00552,1.14843,NO,134,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.969,-3.306,2.337,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.100394,0.00270812,1.14843 kka2_1:8_V16I,kka2_1:8_16,Kka2,kka2_1:8,P00552,1.14847,NO,16,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-3.087,-3.948,0.861,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.100394,0.00694011,1.14847 kka2_1:8_V16I,kka2_1:8_16,Kka2,kka2_1:8,P00552,1.14847,NO,16,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-3.087,-3.948,0.861,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.100394,0.00694011,1.14847 kka2_1:8_F171W,kka2_1:8_171,Kka2,kka2_1:8,P00552,1.14848,NO,171,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.326,-4.742,3.416,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.100394,0.00821426,1.14848 kka2_1:8_F171W,kka2_1:8_171,Kka2,kka2_1:8,P00552,1.14848,NO,171,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.326,-4.742,3.416,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.100394,0.00821426,1.14848 kka2_1:4_C31L,kka2_1:4_31,Kka2,kka2_1:4,P00552,1.14853,NO,31,C,L,CL,Special,Hydrophobic,5.07,9.7088,4.6388,198,121,131,10,108.5,166.7,58.2,-2.246,-3.487,1.241,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.168804,0.00681582,1.14853 kka2_1:8_V16P,kka2_1:8_16,Kka2,kka2_1:8,P00552,1.14853,NO,16,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-3.087,-4.081,0.994,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.100394,0.00694011,1.14853 kka2_1:8_V16P,kka2_1:8_16,Kka2,kka2_1:8,P00552,1.14853,NO,16,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-3.087,-4.081,0.994,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.100394,0.00694011,1.14853 kka2_1:8_L243A,kka2_1:8_243,Kka2,kka2_1:8,P00552,1.14855,NO,243,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-2.651,-2.102,-0.549,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.100394,0.00884927,1.14855 kka2_1:8_L243A,kka2_1:8_243,Kka2,kka2_1:8,P00552,1.14855,NO,243,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-2.651,-2.102,-0.549,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.100394,0.00884927,1.14855 kka2_1:4_V80L,kka2_1:4_80,Kka2,kka2_1:4,P00552,1.14858,NO,80,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.144,-2.831,1.687,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.168804,0.00488211,1.14858 kka2_1:8_E142M,kka2_1:8_142,Kka2,kka2_1:8,P00552,1.14864,NO,142,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.221,-4.819,2.598,,0.471,H,A,1.04,0.85,2.655,,65.53,HAB,-2.08033,0.100394,0.00748883,1.14864 kka2_1:8_E142M,kka2_1:8_142,Kka2,kka2_1:8,P00552,1.14864,NO,142,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.221,-4.819,2.598,,0.471,H,A,1.04,0.85,2.655,,65.53,HAB,-2.08033,0.100394,0.00748883,1.14864 beta-lactamase_0_E62C,beta-lactamase_0_62,TEM-1,beta-lactamase_0,P62593,1.14866,NO,62,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.193,-5.228,4.035,,0.342,S,B,1.04,-0.3,5.784,,73.08,AAB,-1.417,0.0500837,0.00264802,1.14866 kka2_1:4_G95T,kka2_1:4_95,Kka2,kka2_1:4,P00552,1.14874,NO,95,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-2.403,-1.849,-0.554,,0.126,E,B,0.29,-0.74,0.359,,71.59,HOA,-2.198,0.168804,0.00743616,1.14874 beta-lactamase_0_H24D,beta-lactamase_0_24,TEM-1,beta-lactamase_0,P62593,1.14876,NO,24,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-2.481,-2.42,-0.061,,,,,,,2.708,,93.01,OBO,-2.0035,0.0500837,0.00238894,1.14876 beta-lactamase_0_F58G,beta-lactamase_0_58,TEM-1,beta-lactamase_0,P62593,1.14882,NO,58,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-2.914,-3.566,0.652,,0.266,E,B,0.58,-0.07,24.637,24.637,77.62,PHB,-2.059,0.0500837,0.00523369,1.14882 kka2_1:1_C31L,kka2_1:1_31,Kka2,kka2_1:1,P00552,1.14884,NO,31,C,L,CL,Special,Hydrophobic,5.07,9.7088,4.6388,198,121,131,10,108.5,166.7,58.2,-2.246,-3.487,1.241,,1.152,S,b,0.46,4.16,8.272,,63.26,OOP,-1.21533,0.520039,0.00681582,1.14884 kka2_1:8_E230A,kka2_1:8_230,Kka2,kka2_1:8,P00552,1.14894,NO,230,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.672,-2.43,-0.242,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.100394,0.00920051,1.14894 kka2_1:8_E230A,kka2_1:8_230,Kka2,kka2_1:8,P00552,1.14894,NO,230,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.672,-2.43,-0.242,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.100394,0.00920051,1.14894 kka2_1:8_R143K,kka2_1:8_143,Kka2,kka2_1:8,P00552,1.14899,NO,143,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.525,-3.061,0.536,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.100394,0.00662247,1.14899 kka2_1:8_R143K,kka2_1:8_143,Kka2,kka2_1:8,P00552,1.14899,NO,143,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.525,-3.061,0.536,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.100394,0.00662247,1.14899 kka2_1:8_M120L,kka2_1:8_120,Kka2,kka2_1:8,P00552,1.14901,NO,120,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-3.877,-0.807,-3.07,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.100394,0.00265808,1.14901 kka2_1:8_M120L,kka2_1:8_120,Kka2,kka2_1:8,P00552,1.14901,NO,120,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-3.877,-0.807,-3.07,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.100394,0.00265808,1.14901 beta-lactamase_0_M270V,beta-lactamase_0_270,TEM-1,beta-lactamase_0,P62593,1.14902,NO,270,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.0500837,0.00767762,1.14902 kka2_1:4_A9I,kka2_1:4_9,Kka2,kka2_1:4,P00552,1.14905,NO,9,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.079,-2.507,0.428,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.168804,0.00273264,1.14905 beta-lactamase_0_E210T,beta-lactamase_0_210,TEM-1,beta-lactamase_0,P62593,1.14906,NO,210,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.319,-2.842,0.523,,0.476,H,A,1.04,0.75,3.618,,77.62,HAH,-1.88567,0.0500837,0.00663582,1.14906 kka2_1:8_P249W,kka2_1:8_249,Kka2,kka2_1:8,P00552,1.14907,NO,249,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.867,-5.488,3.621,,0.406,.,B,0.52,-0.01,1.699,,92.05,HOA,-1.66867,0.100394,0.011045,1.14907 kka2_1:8_P249W,kka2_1:8_249,Kka2,kka2_1:8,P00552,1.14907,NO,249,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.867,-5.488,3.621,,0.406,.,B,0.52,-0.01,1.699,,92.05,HOA,-1.66867,0.100394,0.011045,1.14907 kka2_1:2_G164H,kka2_1:2_164,Kka2,kka2_1:2,P00552,1.14915,NO,164,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.869,-4.642,3.773,,0.862,T,l,0.75,1.45,1.539,,64.39,POH,-1.828,0.295029,0.00442091,1.14915 kka2_1:8_R177S,kka2_1:8_177,Kka2,kka2_1:8,P00552,1.14927,NO,177,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.282,-2.536,0.254,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.100394,0.00768224,1.14927 kka2_1:8_R177S,kka2_1:8_177,Kka2,kka2_1:8,P00552,1.14927,NO,177,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.282,-2.536,0.254,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.100394,0.00768224,1.14927 kka2_1:4_G6V,kka2_1:4_6,Kka2,kka2_1:4,P00552,1.14928,NO,6,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.685,-3.428,1.743,,,,,,,,,71.59,AOH,-1.639,0.168804,0.00204693,1.14928 kka2_1:8_S40E,kka2_1:8_40,Kka2,kka2_1:8,P00552,1.14929,NO,40,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.645,-2.141,-0.504,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.100394,0.00693477,1.14929 kka2_1:8_S40E,kka2_1:8_40,Kka2,kka2_1:8,P00552,1.14929,NO,40,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.645,-2.141,-0.504,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.100394,0.00693477,1.14929 kka2_1:2_G6F,kka2_1:2_6,Kka2,kka2_1:2,P00552,1.14939,NO,6,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.685,-4.169,2.484,,,,,,,,,71.59,AOH,-1.639,0.295029,0.00204693,1.14939 kka2_1:4_S114R,kka2_1:4_114,Kka2,kka2_1:4,P00552,1.14942,NO,114,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.527,-2.846,0.319,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.168804,0.00705262,1.14942 kka2_1:4_S68T,kka2_1:4_68,Kka2,kka2_1:4,P00552,1.14942,NO,68,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.623,-3.655,1.032,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.168804,0.00608265,1.14942 beta-lactamase_0_Q267A,beta-lactamase_0_267,TEM-1,beta-lactamase_0,P62593,1.14943,NO,267,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.0500837,0.0102128,1.14943 kka2_1:8_R173F,kka2_1:8_173,Kka2,kka2_1:8,P00552,1.14943,NO,173,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.407,-4.245,1.838,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.100394,0.00784999,1.14943 kka2_1:8_R173F,kka2_1:8_173,Kka2,kka2_1:8,P00552,1.14943,NO,173,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.407,-4.245,1.838,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.100394,0.00784999,1.14943 kka2_1:8_V46Q,kka2_1:8_46,Kka2,kka2_1:8,P00552,1.14945,NO,46,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-2.62,-4.138,1.518,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.100394,0.00631301,1.14945 kka2_1:8_V46Q,kka2_1:8_46,Kka2,kka2_1:8,P00552,1.14945,NO,46,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-2.62,-4.138,1.518,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.100394,0.00631301,1.14945 kka2_1:2_W91F,kka2_1:2_91,Kka2,kka2_1:2,P00552,1.14946,NO,91,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-1.178,-2.297,1.119,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.295029,0.00358653,1.14946 beta-lactamase_0_R275E,beta-lactamase_0_275,TEM-1,beta-lactamase_0,P62593,1.14949,NO,275,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.0500837,0.0141984,1.14949 kka2_1:2_Q4D,kka2_1:2_4,Kka2,kka2_1:2,P00552,1.14951,NO,4,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.361,-3.094,0.733,,,,,,,2.026,,71.59,APA,-1.95533,0.295029,0.00239179,1.14951 kka2_1:8_D118T,kka2_1:8_118,Kka2,kka2_1:8,P00552,1.14956,NO,118,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.07,-2.449,0.379,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.100394,0.0067852,1.14956 kka2_1:8_D118T,kka2_1:8_118,Kka2,kka2_1:8,P00552,1.14956,NO,118,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.07,-2.449,0.379,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.100394,0.0067852,1.14956 kka2_1:8_D180R,kka2_1:8_180,Kka2,kka2_1:8,P00552,1.14963,NO,180,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.416,-2.973,0.557,,1.03,S,a,0.75,1.5,14.668,14.668,71.59,OAO,-2.02933,0.100394,0.00756412,1.14963 kka2_1:8_D180R,kka2_1:8_180,Kka2,kka2_1:8,P00552,1.14963,NO,180,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.416,-2.973,0.557,,1.03,S,a,0.75,1.5,14.668,14.668,71.59,OAO,-2.02933,0.100394,0.00756412,1.14963 kka2_1:8_A137Q,kka2_1:8_137,Kka2,kka2_1:8,P00552,1.14967,NO,137,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.156,-4.203,2.047,,0.029,H,A,1.04,0.34,2.886,,63.26,PHB,-2.559,0.100394,0.00515054,1.14967 kka2_1:8_A137Q,kka2_1:8_137,Kka2,kka2_1:8,P00552,1.14967,NO,137,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.156,-4.203,2.047,,0.029,H,A,1.04,0.34,2.886,,63.26,PHB,-2.559,0.100394,0.00515054,1.14967 PSD95pdz3_I389K,PSD95pdz3_389,PSD95pdz3,PSD95pdz3,P31016,1.14968,NO,389,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.628,-3.588,1.96,5.15116,,,,,14.8038,1.498,,87.71,HHH,-1.52167,0.0758425,0.00148097,1.14968 kka2_1:8_L103W,kka2_1:8_103,Kka2,kka2_1:8,P00552,1.14973,NO,103,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-2.362,-5.448,3.086,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.100394,0.00574792,1.14973 kka2_1:8_L103W,kka2_1:8_103,Kka2,kka2_1:8,P00552,1.14973,NO,103,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-2.362,-5.448,3.086,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.100394,0.00574792,1.14973 kka2_1:8_E17D,kka2_1:8_17,Kka2,kka2_1:8,P00552,1.14979,NO,17,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.154,-2.384,0.23,,0.957,T,A,1.04,0.22,31.483,31.483,63.64,HAB,-2.432,0.100394,0.00688738,1.14979 kka2_1:8_E17D,kka2_1:8_17,Kka2,kka2_1:8,P00552,1.14979,NO,17,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.154,-2.384,0.23,,0.957,T,A,1.04,0.22,31.483,31.483,63.64,HAB,-2.432,0.100394,0.00688738,1.14979 kka2_1:2_Q252P,kka2_1:2_252,Kka2,kka2_1:2,P00552,1.14984,NO,252,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.63,-3.996,1.366,,0.906,H,A,0.64,0.35,5.613,,92.05,PPB,-2.20733,0.295029,0.0121001,1.14984 beta-lactamase_0_I206T,beta-lactamase_0_206,TEM-1,beta-lactamase_0,P62593,1.14986,NO,206,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-2.429,-2.077,-0.352,,0.173,H,A,0.48,-0.34,3.411,,77.62,HHA,-1.805,0.0500837,0.00528934,1.14986 beta-lactamase_0_G90F,beta-lactamase_0_90,TEM-1,beta-lactamase_0,P62593,1.14991,NO,90,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-2.091,-4.407,2.316,,0.598,T,A,0.29,0.32,2.04,,77.62,HOB,-1.52633,0.0500837,0.00490273,1.14991 kka2_1:1_A56D,kka2_1:1_56,Kka2,kka2_1:1,P00552,1.14994,NO,56,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.083,-2.651,0.568,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.520039,0.00717715,1.14994 beta-lactamase_0_F228W,beta-lactamase_0_228,TEM-1,beta-lactamase_0,P62593,1.14996,NO,228,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-2.342,-5.275,2.933,,0.154,E,B,0.58,-0.42,15.504,15.504,63.29,HHH,-1.53033,0.0500837,0.0046669,1.14996 kka2_1:4_E230L,kka2_1:4_230,Kka2,kka2_1:4,P00552,1.14996,NO,230,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.672,-3.572,0.9,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.168804,0.00920051,1.14996 kka2_1:2_A172T,kka2_1:2_172,Kka2,kka2_1:2,P00552,1.14998,NO,172,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.757,-2.834,1.077,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.295029,0.0079265,1.14998 kka2_1:8_I2L,kka2_1:8_2,Kka2,kka2_1:8,P00552,1.15001,NO,2,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.787,-2.519,0.732,,,,,,,,,71.59,HHA,-1.92433,0.100394,0.00246644,1.15001 kka2_1:8_I2L,kka2_1:8_2,Kka2,kka2_1:8,P00552,1.15001,NO,2,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.787,-2.519,0.732,,,,,,,,,71.59,HHA,-1.92433,0.100394,0.00246644,1.15001 kka2_1:8_A129T,kka2_1:8_129,Kka2,kka2_1:8,P00552,1.15018,NO,129,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.656,-2.639,0.983,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.100394,0.00726862,1.15018 kka2_1:8_A129T,kka2_1:8_129,Kka2,kka2_1:8,P00552,1.15018,NO,129,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.656,-2.639,0.983,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.100394,0.00726862,1.15018 kka2_1:8_F206W,kka2_1:8_206,Kka2,kka2_1:8,P00552,1.15018,NO,206,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.349,-4.609,3.26,,0.006,E,B,1.62,-1.21,1.052,,63.64,OHH,-1.04,0.100394,0.00936868,1.15018 kka2_1:8_F206W,kka2_1:8_206,Kka2,kka2_1:8,P00552,1.15018,NO,206,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.349,-4.609,3.26,,0.006,E,B,1.62,-1.21,1.052,,63.64,OHH,-1.04,0.100394,0.00936868,1.15018 beta-lactamase_0_E61T,beta-lactamase_0_61,TEM-1,beta-lactamase_0,P62593,1.15019,NO,61,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.115,-3.52,1.405,,0.775,T,a,1.04,1.29,34.763,34.763,77.62,OAA,-1.92567,0.0500837,0.00440955,1.15019 kka2_1:2_A14M,kka2_1:2_14,Kka2,kka2_1:2,P00552,1.15023,NO,14,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.837,-4.736,2.899,,0.728,G,A,0.46,0.7,0.36,,71.59,HHH,-1.82567,0.295029,0.00706614,1.15023 kka2_1:4_G181Q,kka2_1:4_181,Kka2,kka2_1:4,P00552,1.15034,NO,181,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-2.698,-2.961,0.263,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.168804,0.00728319,1.15034 kka2_1:8_A168R,kka2_1:8_168,Kka2,kka2_1:8,P00552,1.15044,NO,168,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.989,-3.003,1.014,,0.67,H,A,0.46,0.15,11.329,11.329,64.39,OHA,-2.12933,0.100394,0.00806773,1.15044 kka2_1:8_A168R,kka2_1:8_168,Kka2,kka2_1:8,P00552,1.15044,NO,168,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.989,-3.003,1.014,,0.67,H,A,0.46,0.15,11.329,11.329,64.39,OHA,-2.12933,0.100394,0.00806773,1.15044 kka2_1:8_E142K,kka2_1:8_142,Kka2,kka2_1:8,P00552,1.15047,NO,142,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.221,-3.543,1.322,,0.471,H,A,1.04,0.85,2.655,,65.53,HAB,-2.08033,0.100394,0.00748883,1.15047 kka2_1:8_E142K,kka2_1:8_142,Kka2,kka2_1:8,P00552,1.15047,NO,142,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.221,-3.543,1.322,,0.471,H,A,1.04,0.85,2.655,,65.53,HAB,-2.08033,0.100394,0.00748883,1.15047 kka2_1:8_G21S,kka2_1:8_21,Kka2,kka2_1:8,P00552,1.15047,NO,21,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.368,-2.431,1.063,,0.586,T,l,0.29,-0.75,4.889,,71.59,HOH,-2.10167,0.100394,0.00709648,1.15047 kka2_1:8_G21S,kka2_1:8_21,Kka2,kka2_1:8,P00552,1.15047,NO,21,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.368,-2.431,1.063,,0.586,T,l,0.29,-0.75,4.889,,71.59,HOH,-2.10167,0.100394,0.00709648,1.15047 kka2_1:8_L57A,kka2_1:8_57,Kka2,kka2_1:8,P00552,1.15047,NO,57,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.898,-3.394,1.496,,0.343,T,A,0.55,0.98,13.359,13.359,52.65,HHP,-2.20733,0.100394,0.00723769,1.15047 kka2_1:8_L57A,kka2_1:8_57,Kka2,kka2_1:8,P00552,1.15047,NO,57,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.898,-3.394,1.496,,0.343,T,A,0.55,0.98,13.359,13.359,52.65,HHP,-2.20733,0.100394,0.00723769,1.15047 kka2_1:2_E231H,kka2_1:2_231,Kka2,kka2_1:2,P00552,1.15058,NO,231,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.002,-4.353,2.351,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.295029,0.00732383,1.15058 kka2_1:8_A9D,kka2_1:8_9,Kka2,kka2_1:8,P00552,1.15061,NO,9,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.079,-3.62,1.541,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.100394,0.00273264,1.15061 kka2_1:8_A9D,kka2_1:8_9,Kka2,kka2_1:8,P00552,1.15061,NO,9,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.079,-3.62,1.541,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.100394,0.00273264,1.15061 kka2_1:4_E169K,kka2_1:4_169,Kka2,kka2_1:4,P00552,1.15064,NO,169,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.996,-2.672,0.676,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.168804,0.00730086,1.15064 beta-lactamase_0_R162H,beta-lactamase_0_162,TEM-1,beta-lactamase_0,P62593,1.15065,NO,162,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.016,-4.37,3.354,,0.124,S,B,1.2,-0.37,1.026,,64.69,ABH,-1.25,0.0500837,0.000561334,1.15065 beta-lactamase_0_E164C,beta-lactamase_0_164,TEM-1,beta-lactamase_0,P62593,1.1507,NO,164,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-0.948,-5.311,4.363,,0.011,T,B,1.04,-0.4,1.011,,64.69,HAO,-1.388,0.0500837,0.00137286,1.1507 beta-lactamase_0_F58M,beta-lactamase_0_58,TEM-1,beta-lactamase_0,P62593,1.15083,NO,58,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-2.914,-4.667,1.753,,0.266,E,B,0.58,-0.07,24.637,24.637,77.62,PHB,-2.059,0.0500837,0.00523369,1.15083 beta-lactamase_0_I244M,beta-lactamase_0_244,TEM-1,beta-lactamase_0,P62593,1.1509,NO,244,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.555,-4.138,2.583,,,E,B,0.48,-0.84,1.241,,77.62,OHH,-1.385,0.0500837,0.00605379,1.1509 kka2_1:2_Q26Y,kka2_1:2_26,Kka2,kka2_1:2,P00552,1.15098,NO,26,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.18,-4.333,2.153,,0.448,E,B,0.4,0.44,5.022,,92.05,HPP,-2.11167,0.295029,0.00708962,1.15098 kka2_1:8_A172F,kka2_1:8_172,Kka2,kka2_1:8,P00552,1.151,NO,172,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.757,-4.4,2.643,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.100394,0.0079265,1.151 kka2_1:8_A172F,kka2_1:8_172,Kka2,kka2_1:8,P00552,1.151,NO,172,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.757,-4.4,2.643,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.100394,0.0079265,1.151 kka2_1:2_S11G,kka2_1:2_11,Kka2,kka2_1:2,P00552,1.15101,NO,11,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.322,-3.427,1.105,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.295029,0.00381691,1.15101 kka2_1:8_K175C,kka2_1:8_175,Kka2,kka2_1:8,P00552,1.15104,NO,175,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-2.897,-2.882,-0.015,,0.579,H,A,2.34,0.51,15.316,15.316,71.59,HBH,-1.82333,0.100394,0.00693093,1.15104 kka2_1:8_K175C,kka2_1:8_175,Kka2,kka2_1:8,P00552,1.15104,NO,175,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-2.897,-2.882,-0.015,,0.579,H,A,2.34,0.51,15.316,15.316,71.59,HBH,-1.82333,0.100394,0.00693093,1.15104 kka2_1:4_P45C,kka2_1:4_45,Kka2,kka2_1:4,P00552,1.15119,NO,45,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.774,-5.158,3.384,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.168804,0.00590481,1.15119 beta-lactamase_0_S57E,beta-lactamase_0_57,TEM-1,beta-lactamase_0,P62593,1.15124,NO,57,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.918,-2.903,0.985,,0.352,E,B,0.27,-0.18,1.454,,72.73,APH,-2.29167,0.0500837,0.00492804,1.15124 beta-lactamase_0_T138E,beta-lactamase_0_138,TEM-1,beta-lactamase_0,P62593,1.15126,NO,138,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.506,-2.168,-0.338,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.0500837,0.00487868,1.15126 kka2_1:8_L7K,kka2_1:8_7,Kka2,kka2_1:8,P00552,1.15126,NO,7,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.926,-3.481,1.555,,,,,,,,,71.59,OHB,-2.12333,0.100394,0.00269456,1.15126 kka2_1:8_L7K,kka2_1:8_7,Kka2,kka2_1:8,P00552,1.15126,NO,7,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.926,-3.481,1.555,,,,,,,,,71.59,OHB,-2.12333,0.100394,0.00269456,1.15126 kka2_1:8_L19V,kka2_1:8_19,Kka2,kka2_1:8,P00552,1.15137,NO,19,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.254,-2.596,1.342,,0.08,T,A,1.59,-0.26,2.044,,65.53,BHH,-2.221,0.100394,0.00620703,1.15137 kka2_1:8_L19V,kka2_1:8_19,Kka2,kka2_1:8,P00552,1.15137,NO,19,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.254,-2.596,1.342,,0.08,T,A,1.59,-0.26,2.044,,65.53,BHH,-2.221,0.100394,0.00620703,1.15137 kka2_1:8_L165N,kka2_1:8_165,Kka2,kka2_1:8,P00552,1.15147,NO,165,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-2.453,-3.932,1.479,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.100394,0.00801161,1.15147 kka2_1:8_L165N,kka2_1:8_165,Kka2,kka2_1:8,P00552,1.15147,NO,165,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-2.453,-3.932,1.479,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.100394,0.00801161,1.15147 kka2_1:8_L243N,kka2_1:8_243,Kka2,kka2_1:8,P00552,1.15147,NO,243,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-2.651,-3.218,0.567,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.100394,0.00884927,1.15147 kka2_1:8_L243N,kka2_1:8_243,Kka2,kka2_1:8,P00552,1.15147,NO,243,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-2.651,-3.218,0.567,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.100394,0.00884927,1.15147 kka2_1:2_E96G,kka2_1:2_96,Kka2,kka2_1:2,P00552,1.1515,NO,96,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.573,-2.57,-0.003,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.295029,0.00369441,1.1515 beta-lactamase_0_A170P,beta-lactamase_0_170,TEM-1,beta-lactamase_0,P62593,1.15155,NO,170,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.237,-3.899,2.662,,0.126,,L,0.46,-0.35,2.427,,64.69,AHH,-1.63267,0.0500837,0.00431903,1.15155 kka2_1:4_Q155P,kka2_1:4_155,Kka2,kka2_1:4,P00552,1.15157,NO,155,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.606,-3.826,1.22,,0.525,T,A,0.64,1.49,1.592,,63.64,APA,-1.726,0.168804,0.00641853,1.15157 kka2_1:8_I29M,kka2_1:8_29,Kka2,kka2_1:8,P00552,1.15157,NO,29,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.692,-3.049,1.357,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.100394,0.00619521,1.15157 kka2_1:8_I29M,kka2_1:8_29,Kka2,kka2_1:8,P00552,1.15157,NO,29,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.692,-3.049,1.357,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.100394,0.00619521,1.15157 beta-lactamase_0_W163H,beta-lactamase_0_163,TEM-1,beta-lactamase_0,P62593,1.15158,NO,163,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-1.843,-3.378,1.535,,0.467,,B,0.47,-0.5,13.843,13.843,63.99,BHA,-1.269,0.0500837,0.00418955,1.15158 beta-lactamase_0_D99R,beta-lactamase_0_99,TEM-1,beta-lactamase_0,P62593,1.15165,NO,99,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.191,-3.828,2.637,,0.402,G,A,0.75,0.36,0.374,,64.69,PAH,-1.794,0.0500837,0.00305446,1.15165 kka2_1:2_A41R,kka2_1:2_41,Kka2,kka2_1:2,P00552,1.15165,NO,41,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.879,-2.71,0.831,,0.184,.,B,0.46,-0.96,24.451,24.451,64.39,PHP,-2.477,0.295029,0.00543332,1.15165 kka2_1:8_A168Y,kka2_1:8_168,Kka2,kka2_1:8,P00552,1.15168,NO,168,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.989,-4.327,2.338,,0.67,H,A,0.46,0.15,11.329,11.329,64.39,OHA,-2.12933,0.100394,0.00806773,1.15168 kka2_1:8_A168Y,kka2_1:8_168,Kka2,kka2_1:8,P00552,1.15168,NO,168,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.989,-4.327,2.338,,0.67,H,A,0.46,0.15,11.329,11.329,64.39,OHA,-2.12933,0.100394,0.00806773,1.15168 kka2_1:4_D250S,kka2_1:4_250,Kka2,kka2_1:4,P00552,1.15169,NO,250,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.015,-2.641,1.626,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.168804,0.0177103,1.15169 beta-lactamase_0_L219S,beta-lactamase_0_219,TEM-1,beta-lactamase_0,P62593,1.152,NO,219,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.313,-3.686,2.373,,,I,A,0.55,-0.51,6.513,6.513,74.48,HHB,-1.21533,0.0500837,0.00664345,1.152 kka2_1:4_A65T,kka2_1:4_65,Kka2,kka2_1:4,P00552,1.15206,NO,65,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.744,-2.824,1.08,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.168804,0.00709258,1.15206 PSD95pdz3_V315F,PSD95pdz3_315,PSD95pdz3,PSD95pdz3,P31016,1.15206,NO,315,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.625,-3.547,1.922,5.52024,,,,,18.4557,4.054,,81.35,HHH,-1.62767,0.0758425,0.00153536,1.15206 beta-lactamase_0_E272S,beta-lactamase_0_272,TEM-1,beta-lactamase_0,P62593,1.15213,NO,272,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.0500837,0.00545371,1.15213 kka2_1:8_A56P,kka2_1:8_56,Kka2,kka2_1:8,P00552,1.15216,NO,56,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.083,-1.768,-0.315,,0.796,T,A,0.46,1.39,10.511,,71.59,OHH,-1.86867,0.100394,0.00717715,1.15216 kka2_1:8_A56P,kka2_1:8_56,Kka2,kka2_1:8,P00552,1.15216,NO,56,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.083,-1.768,-0.315,,0.796,T,A,0.46,1.39,10.511,,71.59,OHH,-1.86867,0.100394,0.00717715,1.15216 kka2_1:8_P249V,kka2_1:8_249,Kka2,kka2_1:8,P00552,1.15219,NO,249,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.867,-2.403,0.536,,0.406,.,B,0.52,-0.01,1.699,,92.05,HOA,-1.66867,0.100394,0.011045,1.15219 kka2_1:8_P249V,kka2_1:8_249,Kka2,kka2_1:8,P00552,1.15219,NO,249,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.867,-2.403,0.536,,0.406,.,B,0.52,-0.01,1.699,,92.05,HOA,-1.66867,0.100394,0.011045,1.15219 kka2_1:8_L103Q,kka2_1:8_103,Kka2,kka2_1:8,P00552,1.15223,NO,103,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-2.362,-4.06,1.698,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.100394,0.00574792,1.15223 kka2_1:8_L103Q,kka2_1:8_103,Kka2,kka2_1:8,P00552,1.15223,NO,103,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-2.362,-4.06,1.698,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.100394,0.00574792,1.15223 kka2_1:8_A166R,kka2_1:8_166,Kka2,kka2_1:8,P00552,1.15225,NO,166,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.407,-3.179,0.772,,0.534,,B,1.04,1.03,13.995,13.995,71.59,HHO,-2.421,0.100394,0.00799912,1.15225 kka2_1:8_A166R,kka2_1:8_166,Kka2,kka2_1:8,P00552,1.15225,NO,166,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.407,-3.179,0.772,,0.534,,B,1.04,1.03,13.995,13.995,71.59,HHO,-2.421,0.100394,0.00799912,1.15225 kka2_1:4_E86H,kka2_1:4_86,Kka2,kka2_1:4,P00552,1.1523,NO,86,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.86,-2.283,0.423,,0.369,.,B,1.04,1.92,4.451,,63.26,PAH,-1.98067,0.168804,0.00642858,1.1523 kka2_1:4_E231H,kka2_1:4_231,Kka2,kka2_1:4,P00552,1.15233,NO,231,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.002,-4.353,2.351,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.168804,0.00732383,1.15233 kka2_1:8_L60I,kka2_1:8_60,Kka2,kka2_1:8,P00552,1.15236,NO,60,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.997,-2.513,1.516,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.100394,0.00262176,1.15236 kka2_1:8_L60I,kka2_1:8_60,Kka2,kka2_1:8,P00552,1.15236,NO,60,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.997,-2.513,1.516,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.100394,0.00262176,1.15236 kka2_1:8_E235C,kka2_1:8_235,Kka2,kka2_1:8,P00552,1.15239,NO,235,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.955,-5.156,3.201,,0.631,H,A,1.52,0.12,,,65.53,OAH,-2.07267,0.100394,0.0102806,1.15239 kka2_1:8_E235C,kka2_1:8_235,Kka2,kka2_1:8,P00552,1.15239,NO,235,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.955,-5.156,3.201,,0.631,H,A,1.52,0.12,,,65.53,OAH,-2.07267,0.100394,0.0102806,1.15239 kka2_1:8_G43E,kka2_1:8_43,Kka2,kka2_1:8,P00552,1.15243,NO,43,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.587,-2.715,1.128,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.100394,0.0071925,1.15243 kka2_1:8_G43E,kka2_1:8_43,Kka2,kka2_1:8,P00552,1.15243,NO,43,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.587,-2.715,1.128,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.100394,0.0071925,1.15243 kka2_1:4_G6K,kka2_1:4_6,Kka2,kka2_1:4,P00552,1.15251,NO,6,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.685,-2.23,0.545,,,,,,,,,71.59,AOH,-1.639,0.168804,0.00204693,1.15251 beta-lactamase_0_D271M,beta-lactamase_0_271,TEM-1,beta-lactamase_0,P62593,1.15259,NO,271,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.0500837,0.00752082,1.15259 kka2_1:4_D180V,kka2_1:4_180,Kka2,kka2_1:4,P00552,1.1526,NO,180,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.416,-3.003,0.587,,1.03,S,a,0.29,1.5,14.668,14.668,71.59,OAO,-2.02933,0.168804,0.00756412,1.1526 beta-lactamase_0_E210C,beta-lactamase_0_210,TEM-1,beta-lactamase_0,P62593,1.15269,NO,210,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.319,-4.991,2.672,,0.476,H,A,1.04,0.75,3.618,,77.62,HAH,-1.88567,0.0500837,0.00663582,1.15269 kka2_1:8_G151K,kka2_1:8_151,Kka2,kka2_1:8,P00552,1.15272,NO,151,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.873,-3.594,2.721,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.100394,0.00339918,1.15272 kka2_1:8_G151K,kka2_1:8_151,Kka2,kka2_1:8,P00552,1.15272,NO,151,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.873,-3.594,2.721,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.100394,0.00339918,1.15272 WW_domain_D194N,WW_domain_194,Yap65,WW_domain,P46937,1.15276,NO,194,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.536,-2.316,0.78,5.95614,,,,,,1.948,,74.4,HAP,-1.78933,0.153962,0.00483742,1.15276 kka2_1:4_A65L,kka2_1:4_65,Kka2,kka2_1:4,P00552,1.15277,NO,65,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.744,-2.62,0.876,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.168804,0.00709258,1.15277 beta-lactamase_0_I244G,beta-lactamase_0_244,TEM-1,beta-lactamase_0,P62593,1.1528,NO,244,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.555,-3.714,2.159,,,E,B,0.48,-0.84,1.241,,77.62,OHH,-1.385,0.0500837,0.00605379,1.1528 kka2_1:8_E161P,kka2_1:8_161,Kka2,kka2_1:8,P00552,1.1528,NO,161,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.581,-2.997,1.416,,0.829,G,A,1.04,2.24,11.923,11.923,92.05,AAB,-1.861,0.100394,0.00760103,1.1528 kka2_1:8_E161P,kka2_1:8_161,Kka2,kka2_1:8,P00552,1.1528,NO,161,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.581,-2.997,1.416,,0.829,G,A,1.04,2.24,11.923,11.923,92.05,AAB,-1.861,0.100394,0.00760103,1.1528 kka2_1:4_I254V,kka2_1:4_254,Kka2,kka2_1:4,P00552,1.15283,NO,254,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.933,-2.29,0.357,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.168804,0.0132375,1.15283 beta-lactamase_0_E145C,beta-lactamase_0_145,TEM-1,beta-lactamase_0,P62593,1.15286,NO,145,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.357,-5.044,2.687,,0.545,H,A,1.04,0.79,1.199,,77.62,BAH,-2.069,0.0500837,0.00553285,1.15286 kka2_1:8_S204M,kka2_1:8_204,Kka2,kka2_1:8,P00552,1.15288,NO,204,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.353,-4.656,3.303,,0.144,E,A,0.27,-1.2,0.368,,65.53,HPO,-0.953333,0.100394,0.00881794,1.15288 kka2_1:8_S204M,kka2_1:8_204,Kka2,kka2_1:8,P00552,1.15288,NO,204,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.353,-4.656,3.303,,0.144,E,A,0.27,-1.2,0.368,,65.53,HPO,-0.953333,0.100394,0.00881794,1.15288 kka2_1:4_L7W,kka2_1:4_7,Kka2,kka2_1:4,P00552,1.1529,NO,7,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.926,-5.046,3.12,,,,,,,3.012,,71.59,OHB,-2.12333,0.168804,0.00269456,1.1529 beta-lactamase_0_N130K,beta-lactamase_0_130,TEM-1,beta-lactamase_0,P62593,1.15292,NO,130,N,K,NK,Polar,PositiveCharge,5.47157,9.74,4.26843,94,132,146,14,114.1,168.6,54.5,-0.798,-3.232,2.434,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.0500837,0.000683376,1.15292 PSD95pdz3_P311R,PSD95pdz3_311,PSD95pdz3,PSD95pdz3,P31016,1.15294,NO,311,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.236,-3.615,2.379,5.76649,,,,,14.78,,,,OOB,-1.409,0.0758425,0.0030796,1.15294 kka2_1:8_Q100N,kka2_1:8_100,Kka2,kka2_1:8,P00552,1.15296,NO,100,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.77,-3.216,0.446,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.100394,0.0066405,1.15296 kka2_1:8_Q100N,kka2_1:8_100,Kka2,kka2_1:8,P00552,1.15296,NO,100,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.77,-3.216,0.446,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.100394,0.0066405,1.15296 kka2_1:8_E235Q,kka2_1:8_235,Kka2,kka2_1:8,P00552,1.15299,NO,235,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.955,-2.458,0.503,,0.631,H,A,1.52,0.12,,,65.53,OAH,-2.07267,0.100394,0.0102806,1.15299 kka2_1:8_E235Q,kka2_1:8_235,Kka2,kka2_1:8,P00552,1.15299,NO,235,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.955,-2.458,0.503,,0.631,H,A,1.52,0.12,,,65.53,OAH,-2.07267,0.100394,0.0102806,1.15299 beta-lactamase_0_I258T,beta-lactamase_0_258,TEM-1,beta-lactamase_0,P62593,1.15304,NO,258,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.0500837,0.007931,1.15304 kka2_1:2_A9Y,kka2_1:2_9,Kka2,kka2_1:2,P00552,1.15313,NO,9,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.079,-4.09,2.011,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.295029,0.00273264,1.15313 beta-lactamase_0_I245F,beta-lactamase_0_245,TEM-1,beta-lactamase_0,P62593,1.15314,NO,245,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.0500837,0.00391032,1.15314 kka2_1:8_D134I,kka2_1:8_134,Kka2,kka2_1:8,P00552,1.15328,NO,134,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.969,-3.956,2.987,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.100394,0.00270812,1.15328 kka2_1:8_D134I,kka2_1:8_134,Kka2,kka2_1:8,P00552,1.15328,NO,134,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.969,-3.956,2.987,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.100394,0.00270812,1.15328 kka2_1:4_V84M,kka2_1:4_84,Kka2,kka2_1:4,P00552,1.15334,NO,84,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-2.279,-4.623,2.344,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.168804,0.00724019,1.15334 kka2_1:4_F171W,kka2_1:4_171,Kka2,kka2_1:4,P00552,1.15335,NO,171,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.326,-4.742,3.416,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.168804,0.00821426,1.15335 kka2_1:8_V84G,kka2_1:8_84,Kka2,kka2_1:8,P00552,1.15344,NO,84,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-2.279,-3.558,1.279,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.100394,0.00724019,1.15344 kka2_1:8_V84G,kka2_1:8_84,Kka2,kka2_1:8,P00552,1.15344,NO,84,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-2.279,-3.558,1.279,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.100394,0.00724019,1.15344 kka2_1:8_Q163W,kka2_1:8_163,Kka2,kka2_1:8,P00552,1.1535,NO,163,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.162,-5.401,3.239,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.100394,0.00719507,1.1535 kka2_1:8_Q163W,kka2_1:8_163,Kka2,kka2_1:8,P00552,1.1535,NO,163,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.162,-5.401,3.239,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.100394,0.00719507,1.1535 kka2_1:8_R202Q,kka2_1:8_202,Kka2,kka2_1:8,P00552,1.15371,NO,202,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.761,-2.622,0.861,,0.607,E,B,1.2,0.48,1.409,,52.27,OBH,-1.41067,0.100394,0.00696498,1.15371 kka2_1:8_R202Q,kka2_1:8_202,Kka2,kka2_1:8,P00552,1.15371,NO,202,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.761,-2.622,0.861,,0.607,E,B,1.2,0.48,1.409,,52.27,OBH,-1.41067,0.100394,0.00696498,1.15371 kka2_1:8_A14Y,kka2_1:8_14,Kka2,kka2_1:8,P00552,1.15378,NO,14,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.837,-4.418,2.581,,0.728,G,A,0.46,0.7,,,71.59,HHH,-1.82567,0.100394,0.00706614,1.15378 kka2_1:8_A14Y,kka2_1:8_14,Kka2,kka2_1:8,P00552,1.15378,NO,14,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.837,-4.418,2.581,,0.728,G,A,0.46,0.7,,,71.59,HHH,-1.82567,0.100394,0.00706614,1.15378 kka2_1:2_F20V,kka2_1:2_20,Kka2,kka2_1:2,P00552,1.15381,NO,20,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-3.354,-2.808,-0.546,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.295029,0.00701744,1.15381 kka2_1:8_S114Q,kka2_1:8_114,Kka2,kka2_1:8,P00552,1.15381,NO,114,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.527,-3.268,0.741,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.100394,0.00705262,1.15381 kka2_1:8_S114Q,kka2_1:8_114,Kka2,kka2_1:8,P00552,1.15381,NO,114,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.527,-3.268,0.741,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.100394,0.00705262,1.15381 kka2_1:4_A56I,kka2_1:4_56,Kka2,kka2_1:4,P00552,1.15382,NO,56,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.083,-3.881,1.798,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.168804,0.00717715,1.15382 kka2_1:8_A255Q,kka2_1:8_255,Kka2,kka2_1:8,P00552,1.15391,NO,255,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.715,-4.01,2.295,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.100394,0.0126809,1.15391 kka2_1:8_A255Q,kka2_1:8_255,Kka2,kka2_1:8,P00552,1.15391,NO,255,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.715,-4.01,2.295,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.100394,0.0126809,1.15391 kka2_1:8_Q42N,kka2_1:8_42,Kka2,kka2_1:8,P00552,1.15391,NO,42,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.907,-2.98,0.073,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.100394,0.00679212,1.15391 kka2_1:8_Q42N,kka2_1:8_42,Kka2,kka2_1:8,P00552,1.15391,NO,42,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.907,-2.98,0.073,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.100394,0.00679212,1.15391 beta-lactamase_0_L167M,beta-lactamase_0_167,TEM-1,beta-lactamase_0,P62593,1.15394,NO,167,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.138,-2.673,1.535,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.0500837,0.00303566,1.15394 beta-lactamase_0_A278N,beta-lactamase_0_278,TEM-1,beta-lactamase_0,P62593,1.15404,NO,278,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.348,,,,0.015,H,A,0.48,-0.85,4.624,,63.29,HHA,-1.41833,0.0500837,0.0310297,1.15404 kka2_1:4_Q136R,kka2_1:4_136,Kka2,kka2_1:4,P00552,1.15405,NO,136,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-3.021,-1.428,-1.593,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.168804,0.00624149,1.15405 kka2_1:8_L7R,kka2_1:8_7,Kka2,kka2_1:8,P00552,1.15411,NO,7,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.926,-3.722,1.796,,,,,,,,,71.59,OHB,-2.12333,0.100394,0.00269456,1.15411 kka2_1:8_L7R,kka2_1:8_7,Kka2,kka2_1:8,P00552,1.15411,NO,7,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.926,-3.722,1.796,,,,,,,,,71.59,OHB,-2.12333,0.100394,0.00269456,1.15411 kka2_1:4_P45G,kka2_1:4_45,Kka2,kka2_1:4,P00552,1.15415,NO,45,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.774,-2.532,0.758,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.168804,0.00590481,1.15415 kka2_1:2_T85E,kka2_1:2_85,Kka2,kka2_1:2,P00552,1.15418,NO,85,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.165,-2.512,0.347,,0.576,E,B,0.22,1.39,1.853,,71.59,HPA,-2.10133,0.295029,0.00634493,1.15418 kka2_1:8_C31G,kka2_1:8_31,Kka2,kka2_1:8,P00552,1.15418,NO,31,C,G,CG,Special,Special,5.07,3.29388,-1.77612,159,121,75,-46,108.5,60.1,-48.4,-2.246,-3.573,1.327,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.100394,0.00681582,1.15418 kka2_1:8_C31G,kka2_1:8_31,Kka2,kka2_1:8,P00552,1.15418,NO,31,C,G,CG,Special,Special,5.07,3.29388,-1.77612,159,121,75,-46,108.5,60.1,-48.4,-2.246,-3.573,1.327,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.100394,0.00681582,1.15418 kka2_1:2_A79Q,kka2_1:2_79,Kka2,kka2_1:2,P00552,1.15423,NO,79,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.368,-2.757,0.389,,0.563,.,B,0.46,-0.43,0.475,,71.59,HHH,-1.752,0.295029,0.00664821,1.15423 beta-lactamase_0_S80R,beta-lactamase_0_80,TEM-1,beta-lactamase_0,P62593,1.15442,NO,80,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.029,-3.076,1.047,,0.192,H,A,0.27,0.46,12.403,12.403,77.62,HPB,-1.44567,0.0500837,0.00565569,1.15442 beta-lactamase_0_M67G,beta-lactamase_0_67,TEM-1,beta-lactamase_0,P62593,1.15448,NO,67,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-2.231,-2.754,0.523,,0.006,G,P,0.55,-0.81,24.165,24.165,65.03,HHP,-1.502,0.0500837,0.00409753,1.15448 kka2_1:8_Q27I,kka2_1:8_27,Kka2,kka2_1:8,P00552,1.1545,NO,27,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-1.659,-3.006,1.347,,0.608,.,A,0.64,0.71,3.919,,65.53,PPP,-1.90733,0.100394,0.00595365,1.1545 kka2_1:8_Q27I,kka2_1:8_27,Kka2,kka2_1:8,P00552,1.1545,NO,27,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-1.659,-3.006,1.347,,0.608,.,A,0.64,0.71,3.919,,65.53,PPP,-1.90733,0.100394,0.00595365,1.1545 beta-lactamase_0_G236H,beta-lactamase_0_236,TEM-1,beta-lactamase_0,P62593,1.15453,NO,236,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.784,-4.704,3.92,,0.241,,b,0.29,-0.59,3.506,,64.69,HOO,-1.025,0.0500837,0.00162372,1.15453 kka2_1:4_D5A,kka2_1:4_5,Kka2,kka2_1:4,P00552,1.15455,NO,5,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.306,-3.033,1.727,,,,,,,,,71.59,PAO,-1.784,0.168804,0.00222864,1.15455 kka2_1:8_A176I,kka2_1:8_176,Kka2,kka2_1:8,P00552,1.15456,NO,176,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.621,-4.019,2.398,,0.806,H,A,0.46,-0.03,18.904,18.904,65.53,BHB,-2.26667,0.100394,0.0083587,1.15456 kka2_1:8_A176I,kka2_1:8_176,Kka2,kka2_1:8,P00552,1.15456,NO,176,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.621,-4.019,2.398,,0.806,H,A,0.46,-0.03,18.904,18.904,65.53,BHB,-2.26667,0.100394,0.0083587,1.15456 kka2_1:8_T72K,kka2_1:8_72,Kka2,kka2_1:8,P00552,1.15459,NO,72,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.38,-2.635,0.255,,0.784,H,A,0.22,0.29,3.603,,65.53,HPP,-2.238,0.100394,0.00750756,1.15459 kka2_1:8_T72K,kka2_1:8_72,Kka2,kka2_1:8,P00552,1.15459,NO,72,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.38,-2.635,0.255,,0.784,H,A,0.22,0.29,3.603,,65.53,HPP,-2.238,0.100394,0.00750756,1.15459 kka2_1:8_R202C,kka2_1:8_202,Kka2,kka2_1:8,P00552,1.15461,NO,202,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.761,-3.597,1.836,,0.607,E,B,1.2,0.48,1.409,,52.27,OBH,-1.41067,0.100394,0.00696498,1.15461 kka2_1:8_R202C,kka2_1:8_202,Kka2,kka2_1:8,P00552,1.15461,NO,202,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.761,-3.597,1.836,,0.607,E,B,1.2,0.48,1.409,,52.27,OBH,-1.41067,0.100394,0.00696498,1.15461 beta-lactamase_0_R176D,beta-lactamase_0_176,TEM-1,beta-lactamase_0,P62593,1.15465,NO,176,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-0.863,-3.694,2.831,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.0500837,0.00105554,1.15465 kka2_1:8_K138R,kka2_1:8_138,Kka2,kka2_1:8,P00552,1.15474,NO,138,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-2.5,-3.18,0.68,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.100394,0.00628542,1.15474 kka2_1:8_K138R,kka2_1:8_138,Kka2,kka2_1:8,P00552,1.15474,NO,138,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-2.5,-3.18,0.68,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.100394,0.00628542,1.15474 kka2_1:4_C31N,kka2_1:4_31,Kka2,kka2_1:4,P00552,1.15493,NO,31,C,N,CN,Special,Polar,5.07,5.47157,0.401575,139,121,132,11,108.5,114.1,5.6,-2.246,-3.833,1.587,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.168804,0.00681582,1.15493 kka2_1:8_E231C,kka2_1:8_231,Kka2,kka2_1:8,P00552,1.15494,NO,231,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.002,-3.282,1.28,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.100394,0.00732383,1.15494 kka2_1:8_E231C,kka2_1:8_231,Kka2,kka2_1:8,P00552,1.15494,NO,231,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.002,-3.282,1.28,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.100394,0.00732383,1.15494 kka2_1:8_T72M,kka2_1:8_72,Kka2,kka2_1:8,P00552,1.15494,NO,72,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.38,-3.59,1.21,,0.784,H,A,0.22,0.29,3.603,,65.53,HPP,-2.238,0.100394,0.00750756,1.15494 kka2_1:8_T72M,kka2_1:8_72,Kka2,kka2_1:8,P00552,1.15494,NO,72,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.38,-3.59,1.21,,0.784,H,A,0.22,0.29,3.603,,65.53,HPP,-2.238,0.100394,0.00750756,1.15494 beta-lactamase_0_R239D,beta-lactamase_0_239,TEM-1,beta-lactamase_0,P62593,1.15496,NO,239,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.0500837,0.00213852,1.15496 kka2_1:8_P249F,kka2_1:8_249,Kka2,kka2_1:8,P00552,1.15496,NO,249,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.867,-3.04,1.173,,0.406,.,B,0.52,-0.01,1.699,,92.05,HOA,-1.66867,0.100394,0.011045,1.15496 kka2_1:8_P249F,kka2_1:8_249,Kka2,kka2_1:8,P00552,1.15496,NO,249,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.867,-3.04,1.173,,0.406,.,B,0.52,-0.01,1.699,,92.05,HOA,-1.66867,0.100394,0.011045,1.15496 kka2_1:4_P45Q,kka2_1:4_45,Kka2,kka2_1:4,P00552,1.15497,NO,45,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.774,-2.806,1.032,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.168804,0.00590481,1.15497 kka2_1:4_K175M,kka2_1:4_175,Kka2,kka2_1:4,P00552,1.15498,NO,175,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-2.897,-3.26,0.363,,0.579,H,A,1.3,0.51,15.629,15.629,71.59,HBH,-1.82333,0.168804,0.00693093,1.15498 kka2_1:8_E169H,kka2_1:8_169,Kka2,kka2_1:8,P00552,1.15502,NO,169,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.996,-4.724,2.728,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.100394,0.00730086,1.15502 kka2_1:8_E169H,kka2_1:8_169,Kka2,kka2_1:8,P00552,1.15502,NO,169,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.996,-4.724,2.728,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.100394,0.00730086,1.15502 kka2_1:4_V49M,kka2_1:4_49,Kka2,kka2_1:4,P00552,1.15505,NO,49,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.614,-4.13,2.516,,,E,B,0.44,-0.77,1.233,,64.39,HHB,-1.3,0.168804,0.00615685,1.15505 kka2_1:8_L103C,kka2_1:8_103,Kka2,kka2_1:8,P00552,1.15509,NO,103,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-2.362,-4.794,2.432,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.100394,0.00574792,1.15509 kka2_1:8_L103C,kka2_1:8_103,Kka2,kka2_1:8,P00552,1.15509,NO,103,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-2.362,-4.794,2.432,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.100394,0.00574792,1.15509 kka2_1:2_A176T,kka2_1:2_176,Kka2,kka2_1:2,P00552,1.15513,NO,176,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.621,-2.528,0.907,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.295029,0.0083587,1.15513 kka2_1:8_P167I,kka2_1:8_167,Kka2,kka2_1:8,P00552,1.15516,NO,167,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-2.403,-2.742,0.339,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.100394,0.00543203,1.15516 kka2_1:8_P167I,kka2_1:8_167,Kka2,kka2_1:8,P00552,1.15516,NO,167,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-2.403,-2.742,0.339,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.100394,0.00543203,1.15516 kka2_1:8_I141V,kka2_1:8_141,Kka2,kka2_1:8,P00552,1.15519,NO,141,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.495,-1.912,0.417,,0.068,H,A,1.52,-0.01,2.144,,92.05,BHA,-1.689,0.100394,0.00744745,1.15519 kka2_1:8_I141V,kka2_1:8_141,Kka2,kka2_1:8,P00552,1.15519,NO,141,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.495,-1.912,0.417,,0.068,H,A,1.52,-0.01,2.144,,92.05,BHA,-1.689,0.100394,0.00744745,1.15519 kka2_1:8_Q155L,kka2_1:8_155,Kka2,kka2_1:8,P00552,1.15525,NO,155,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.606,-3.573,0.967,,0.525,T,A,0.64,1.49,,,63.64,APA,-1.726,0.100394,0.00641853,1.15525 kka2_1:8_Q155L,kka2_1:8_155,Kka2,kka2_1:8,P00552,1.15525,NO,155,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.606,-3.573,0.967,,0.525,T,A,0.64,1.49,,,63.64,APA,-1.726,0.100394,0.00641853,1.15525 kka2_1:2_P249A,kka2_1:2_249,Kka2,kka2_1:2,P00552,1.15539,NO,249,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.867,-2.101,0.234,,0.406,.,B,0.52,-0.01,0.76,,92.05,HOA,-1.66867,0.295029,0.011045,1.15539 kka2_1:8_I141C,kka2_1:8_141,Kka2,kka2_1:8,P00552,1.15547,NO,141,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.495,-4.812,3.317,,0.068,H,A,1.52,-0.01,2.144,,92.05,BHA,-1.689,0.100394,0.00744745,1.15547 kka2_1:8_I141C,kka2_1:8_141,Kka2,kka2_1:8,P00552,1.15547,NO,141,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.495,-4.812,3.317,,0.068,H,A,1.52,-0.01,2.144,,92.05,BHA,-1.689,0.100394,0.00744745,1.15547 kka2_1:8_H8R,kka2_1:8_8,Kka2,kka2_1:8,P00552,1.15556,NO,8,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-2.759,-3.714,0.955,,,,,,,,,71.59,HBH,-2.25467,0.100394,0.00256422,1.15556 kka2_1:8_H8R,kka2_1:8_8,Kka2,kka2_1:8,P00552,1.15556,NO,8,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-2.759,-3.714,0.955,,,,,,,,,71.59,HBH,-2.25467,0.100394,0.00256422,1.15556 beta-lactamase_0_E108A,beta-lactamase_0_108,TEM-1,beta-lactamase_0,P62593,1.15557,NO,108,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.46,-2.613,1.153,,0.572,G,A,1.04,1.87,8.602,8.602,72.73,PAB,-1.437,0.0500837,0.00413372,1.15557 kka2_1:8_G234E,kka2_1:8_234,Kka2,kka2_1:8,P00552,1.15564,NO,234,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-2.9,-1.763,-1.137,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.100394,0.00984449,1.15564 kka2_1:8_G234E,kka2_1:8_234,Kka2,kka2_1:8,P00552,1.15564,NO,234,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-2.9,-1.763,-1.137,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.100394,0.00984449,1.15564 kka2_1:8_R18W,kka2_1:8_18,Kka2,kka2_1:8,P00552,1.15564,NO,18,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.055,-5.448,3.393,,0.474,T,A,1.2,0.54,19.629,19.629,71.59,ABH,-1.821,0.100394,0.00724065,1.15564 kka2_1:8_R18W,kka2_1:8_18,Kka2,kka2_1:8,P00552,1.15564,NO,18,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.055,-5.448,3.393,,0.474,T,A,1.2,0.54,19.629,19.629,71.59,ABH,-1.821,0.100394,0.00724065,1.15564 beta-lactamase_0_N152M,beta-lactamase_0_152,TEM-1,beta-lactamase_0,P62593,1.15573,NO,152,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-2.757,-4.737,1.98,,0.863,H,A,0.61,0.92,2.151,,77.62,BPH,-2.97,0.0500837,0.00471429,1.15573 kka2_1:2_M178L,kka2_1:2_178,Kka2,kka2_1:2,P00552,1.15574,NO,178,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-3.206,-2.71,-0.496,,0.554,.,b,0.55,0.68,3.152,,71.59,BHO,-2.154,0.295029,0.00717253,1.15574 kka2_1:8_D250A,kka2_1:8_250,Kka2,kka2_1:8,P00552,1.15577,NO,250,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.015,-3.315,2.3,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.100394,0.0177103,1.15577 kka2_1:8_D250A,kka2_1:8_250,Kka2,kka2_1:8,P00552,1.15577,NO,250,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.015,-3.315,2.3,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.100394,0.0177103,1.15577 beta-lactamase_0_S51V,beta-lactamase_0_51,TEM-1,beta-lactamase_0,P62593,1.15578,NO,51,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.526,-3.559,2.033,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.0500837,0.00504821,1.15578 kka2_1:8_V75F,kka2_1:8_75,Kka2,kka2_1:8,P00552,1.15579,NO,75,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-2.06,-2.827,0.767,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.100394,0.00693733,1.15579 kka2_1:8_V75F,kka2_1:8_75,Kka2,kka2_1:8,P00552,1.15579,NO,75,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-2.06,-2.827,0.767,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.100394,0.00693733,1.15579 beta-lactamase_0_P217H,beta-lactamase_0_217,TEM-1,beta-lactamase_0,P62593,1.1558,NO,217,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-2.062,-3.354,1.292,,0.496,I,A,0.52,-0.33,1.087,,74.48,OOH,-1.64333,0.0500837,0.00463211,1.1558 beta-lactamase_0_E238S,beta-lactamase_0_238,TEM-1,beta-lactamase_0,P62593,1.15582,NO,238,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.0500837,0.00743256,1.15582 kka2_1:4_E231T,kka2_1:4_231,Kka2,kka2_1:4,P00552,1.15582,NO,231,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.002,-3.44,1.438,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.168804,0.00732383,1.15582 kka2_1:2_Q61C,kka2_1:2_61,Kka2,kka2_1:2,P00552,1.1559,NO,61,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.982,-5.1,2.118,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.295029,0.00612092,1.1559 kka2_1:8_T146D,kka2_1:8_146,Kka2,kka2_1:8,P00552,1.15594,NO,146,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.978,-3.05,0.072,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.100394,0.00606474,1.15594 kka2_1:8_T146D,kka2_1:8_146,Kka2,kka2_1:8,P00552,1.15594,NO,146,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.978,-3.05,0.072,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.100394,0.00606474,1.15594 kka2_1:4_R202C,kka2_1:4_202,Kka2,kka2_1:4,P00552,1.15596,NO,202,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.761,-3.597,1.836,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.168804,0.00696498,1.15596 gb1_D266F,gb1_266,gb1,gb1,P06654,1.15597,NO,266,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.261,-3.535,2.274,,,,,,,0.638,,45.54,HAO,-1.59333,0.177985,0.00394694,1.15597 kka2_1:8_E235P,kka2_1:8_235,Kka2,kka2_1:8,P00552,1.15606,NO,235,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.955,-2.919,0.964,,0.631,H,A,1.52,0.12,,,65.53,OAH,-2.07267,0.100394,0.0102806,1.15606 kka2_1:8_E235P,kka2_1:8_235,Kka2,kka2_1:8,P00552,1.15606,NO,235,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.955,-2.919,0.964,,0.631,H,A,1.52,0.12,,,65.53,OAH,-2.07267,0.100394,0.0102806,1.15606 kka2_1:8_D23E,kka2_1:8_23,Kka2,kka2_1:8,P00552,1.15614,NO,23,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.459,-2.431,-0.028,,0.695,E,B,0.75,-0.65,,,65.53,HAH,-1.94033,0.100394,0.007195,1.15614 kka2_1:8_D23E,kka2_1:8_23,Kka2,kka2_1:8,P00552,1.15614,NO,23,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.459,-2.431,-0.028,,0.695,E,B,0.75,-0.65,,,65.53,HAH,-1.94033,0.100394,0.007195,1.15614 kka2_1:4_A150F,kka2_1:4_150,Kka2,kka2_1:4,P00552,1.1562,NO,150,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.949,-4.228,3.279,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.168804,0.0045009,1.1562 kka2_1:8_D238N,kka2_1:8_238,Kka2,kka2_1:8,P00552,1.1562,NO,238,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.83,-3.158,0.328,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.100394,0.0113863,1.1562 kka2_1:8_D238N,kka2_1:8_238,Kka2,kka2_1:8,P00552,1.1562,NO,238,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.83,-3.158,0.328,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.100394,0.0113863,1.1562 kka2_1:2_Q163H,kka2_1:2_163,Kka2,kka2_1:2,P00552,1.15631,NO,163,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.162,-4.775,2.613,,0.58,T,B,0.64,1.85,3.888,,64.02,BPO,-1.78333,0.295029,0.00719507,1.15631 kka2_1:2_Q163W,kka2_1:2_163,Kka2,kka2_1:2,P00552,1.15638,NO,163,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.162,-5.401,3.239,,0.58,T,B,0.64,1.85,3.888,,64.02,BPO,-1.78333,0.295029,0.00719507,1.15638 kka2_1:2_A35G,kka2_1:2_35,Kka2,kka2_1:2,P00552,1.1564,NO,35,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.127,-2.532,0.405,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.295029,0.00630016,1.1564 kka2_1:8_E199Y,kka2_1:8_199,Kka2,kka2_1:8,P00552,1.1564,NO,199,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.234,-4.316,2.082,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.100394,0.00854122,1.1564 kka2_1:8_E199Y,kka2_1:8_199,Kka2,kka2_1:8,P00552,1.1564,NO,199,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.234,-4.316,2.082,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.100394,0.00854122,1.1564 beta-lactamase_0_V260M,beta-lactamase_0_260,TEM-1,beta-lactamase_0,P62593,1.15641,NO,260,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.101,,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.0500837,0.00471757,1.15641 kka2_1:2_V16M,kka2_1:2_16,Kka2,kka2_1:2,P00552,1.15652,NO,16,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-3.087,-3.551,0.464,,0.742,T,A,0.44,0.34,1.746,,71.59,HHA,-2.211,0.295029,0.00694011,1.15652 beta-lactamase_0_L100G,beta-lactamase_0_100,TEM-1,beta-lactamase_0,P62593,1.15658,NO,100,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.218,-3.854,2.636,,0.343,,B,0.55,0.13,1.373,,63.29,AHH,-1.23467,0.0500837,0.00413885,1.15658 beta-lactamase_0_F149Y,beta-lactamase_0_149,TEM-1,beta-lactamase_0,P62593,1.15671,NO,149,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.299,-1.705,0.406,,0.195,H,A,0.58,0.11,3.518,,63.99,HHH,-1.46067,0.0500837,0.00418462,1.15671 kka2_1:8_A108R,kka2_1:8_108,Kka2,kka2_1:8,P00552,1.15672,NO,108,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.061,-4.036,1.975,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.100394,0.00751209,1.15672 kka2_1:8_A108R,kka2_1:8_108,Kka2,kka2_1:8,P00552,1.15672,NO,108,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.061,-4.036,1.975,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.100394,0.00751209,1.15672 kka2_1:2_G234K,kka2_1:2_234,Kka2,kka2_1:2,P00552,1.15675,NO,234,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-2.9,-2.482,-0.418,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.295029,0.00984449,1.15675 kka2_1:8_E230Y,kka2_1:8_230,Kka2,kka2_1:8,P00552,1.15683,NO,230,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.672,-2.09,-0.582,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.100394,0.00920051,1.15683 kka2_1:8_E230Y,kka2_1:8_230,Kka2,kka2_1:8,P00552,1.15683,NO,230,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.672,-2.09,-0.582,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.100394,0.00920051,1.15683 kka2_1:4_V75H,kka2_1:4_75,Kka2,kka2_1:4,P00552,1.15684,NO,75,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-2.06,-4.952,2.892,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.168804,0.00693733,1.15684 kka2_1:8_R173I,kka2_1:8_173,Kka2,kka2_1:8,P00552,1.1569,NO,173,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.407,-4.054,1.647,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.100394,0.00784999,1.1569 kka2_1:8_R173I,kka2_1:8_173,Kka2,kka2_1:8,P00552,1.1569,NO,173,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.407,-4.054,1.647,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.100394,0.00784999,1.1569 beta-lactamase_0_V31I,beta-lactamase_0_31,TEM-1,beta-lactamase_0,P62593,1.15705,NO,31,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.822,-1.838,0.016,,,H,A,0.44,-0.46,4.126,,73.78,BHB,-2.03767,0.0500837,0.00478065,1.15705 kka2_1:8_F37Y,kka2_1:8_37,Kka2,kka2_1:8,P00552,1.15708,NO,37,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.427,-2.628,1.201,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.100394,0.00586193,1.15708 kka2_1:8_F37Y,kka2_1:8_37,Kka2,kka2_1:8,P00552,1.15708,NO,37,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.427,-2.628,1.201,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.100394,0.00586193,1.15708 WW_domain_S183Q,WW_domain_183,Yap65,WW_domain,P46937,1.15708,NO,183,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.95,-3.786,1.836,5.35576,,,,,,1.594,,83.93,PPP,-1.48733,0.153962,0.00445513,1.15708 kka2_1:2_S54K,kka2_1:2_54,Kka2,kka2_1:2,P00552,1.1571,NO,54,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.471,-3.67,1.199,,0.408,S,b,0.27,1.01,0.393,,71.59,HPO,-2.259,0.295029,0.00782867,1.1571 kka2_1:8_V80R,kka2_1:8_80,Kka2,kka2_1:8,P00552,1.1571,NO,80,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.144,-4.199,3.055,,0.358,E,B,1.48,-0.24,2.562,,63.64,HHH,-1.64633,0.100394,0.00488211,1.1571 kka2_1:8_V80R,kka2_1:8_80,Kka2,kka2_1:8,P00552,1.1571,NO,80,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.144,-4.199,3.055,,0.358,E,B,1.48,-0.24,2.562,,63.64,HHH,-1.64633,0.100394,0.00488211,1.1571 kka2_1:2_S40N,kka2_1:2_40,Kka2,kka2_1:2,P00552,1.15733,NO,40,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.645,-3.752,1.107,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.295029,0.00693477,1.15733 kka2_1:4_G74P,kka2_1:4_74,Kka2,kka2_1:4,P00552,1.15733,NO,74,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.18,-3.953,2.773,,0.621,T,l,0.75,0.2,1.032,,64.39,POH,-1.91667,0.168804,0.00587035,1.15733 kka2_1:4_G181S,kka2_1:4_181,Kka2,kka2_1:4,P00552,1.15734,NO,181,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-2.698,-2.485,-0.213,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.168804,0.00728319,1.15734 kka2_1:8_Y218F,kka2_1:8_218,Kka2,kka2_1:8,P00552,1.15734,NO,218,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-1.438,-2.611,1.173,,0.122,H,A,1.25,-0.69,2.923,,56.06,BHP,-1.17533,0.100394,0.0126098,1.15734 kka2_1:8_Y218F,kka2_1:8_218,Kka2,kka2_1:8,P00552,1.15734,NO,218,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-1.438,-2.611,1.173,,0.122,H,A,1.25,-0.69,2.923,,56.06,BHP,-1.17533,0.100394,0.0126098,1.15734 kka2_1:8_I2R,kka2_1:8_2,Kka2,kka2_1:8,P00552,1.15735,NO,2,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.787,-3.848,2.061,,,,,,,,,71.59,HHA,-1.92433,0.100394,0.00246644,1.15735 kka2_1:8_I2R,kka2_1:8_2,Kka2,kka2_1:8,P00552,1.15735,NO,2,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.787,-3.848,2.061,,,,,,,,,71.59,HHA,-1.92433,0.100394,0.00246644,1.15735 gb1_D266H,gb1_266,gb1,gb1,P06654,1.15736,NO,266,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.261,-4.052,2.791,,,,,,,0.638,,45.54,HAO,-1.59333,0.177985,0.00394694,1.15736 kka2_1:4_A168W,kka2_1:4_168,Kka2,kka2_1:4,P00552,1.15736,NO,168,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.989,-5.548,3.559,,0.67,H,A,0.46,0.15,,,64.39,OHA,-2.12933,0.168804,0.00806773,1.15736 kka2_1:8_I254V,kka2_1:8_254,Kka2,kka2_1:8,P00552,1.15753,NO,254,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.933,-2.29,0.357,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.100394,0.0132375,1.15753 kka2_1:8_I254V,kka2_1:8_254,Kka2,kka2_1:8,P00552,1.15753,NO,254,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.933,-2.29,0.357,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.100394,0.0132375,1.15753 kka2_1:4_A168V,kka2_1:4_168,Kka2,kka2_1:4,P00552,1.15758,NO,168,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.989,-3.131,1.142,,0.67,H,A,0.46,0.15,,,64.39,OHA,-2.12933,0.168804,0.00806773,1.15758 kka2_1:2_Q136T,kka2_1:2_136,Kka2,kka2_1:2,P00552,1.15768,NO,136,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-3.021,-2.627,-0.394,,0.331,,b,0.4,0.96,2.726,,92.05,BPH,-2.16933,0.295029,0.00624149,1.15768 kka2_1:8_D134K,kka2_1:8_134,Kka2,kka2_1:8,P00552,1.15771,NO,134,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.969,-3.503,2.534,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.100394,0.00270812,1.15771 kka2_1:8_D134K,kka2_1:8_134,Kka2,kka2_1:8,P00552,1.15771,NO,134,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.969,-3.503,2.534,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.100394,0.00270812,1.15771 kka2_1:4_G164W,kka2_1:4_164,Kka2,kka2_1:4,P00552,1.15775,NO,164,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.869,-5.307,4.438,,0.862,T,l,0.75,1.45,1.539,,64.39,POH,-1.828,0.168804,0.00442091,1.15775 kka2_1:8_A168C,kka2_1:8_168,Kka2,kka2_1:8,P00552,1.15783,NO,168,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.989,-5.174,3.185,,0.67,H,A,0.46,0.15,11.329,11.329,64.39,OHA,-2.12933,0.100394,0.00806773,1.15783 kka2_1:8_A168C,kka2_1:8_168,Kka2,kka2_1:8,P00552,1.15783,NO,168,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.989,-5.174,3.185,,0.67,H,A,0.46,0.15,11.329,11.329,64.39,OHA,-2.12933,0.100394,0.00806773,1.15783 kka2_1:4_L81R,kka2_1:4_81,Kka2,kka2_1:4,P00552,1.15794,NO,81,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.427,-4.145,2.718,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.168804,0.00805839,1.15794 beta-lactamase_0_L196I,beta-lactamase_0_196,TEM-1,beta-lactamase_0,P62593,1.15808,NO,196,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-2.478,-2.648,0.17,,0.518,S,A,0.55,1.35,6.513,6.513,77.62,AHH,-1.839,0.0500837,0.00512144,1.15808 beta-lactamase_0_Q203V,beta-lactamase_0_203,TEM-1,beta-lactamase_0,P62593,1.1583,NO,203,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.168,-3.605,1.437,,0.47,H,A,0.64,-0.38,14.541,14.541,65.38,BPP,-1.614,0.0500837,0.00631514,1.1583 kka2_1:4_P45A,kka2_1:4_45,Kka2,kka2_1:4,P00552,1.15835,NO,45,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.774,-2.227,0.453,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.168804,0.00590481,1.15835 kka2_1:8_Q252R,kka2_1:8_252,Kka2,kka2_1:8,P00552,1.15839,NO,252,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.63,-2.449,-0.181,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.100394,0.0121001,1.15839 kka2_1:8_Q252R,kka2_1:8_252,Kka2,kka2_1:8,P00552,1.15839,NO,252,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.63,-2.449,-0.181,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.100394,0.0121001,1.15839 kka2_1:8_P12L,kka2_1:8_12,Kka2,kka2_1:8,P00552,1.1584,NO,12,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.853,-3.533,2.68,,,.,B,0.52,1.25,2.41,,48.11,POH,-1.80767,0.100394,0.00500011,1.1584 kka2_1:8_P12L,kka2_1:8_12,Kka2,kka2_1:8,P00552,1.1584,NO,12,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-0.853,-3.533,2.68,,,.,B,0.52,1.25,2.41,,48.11,POH,-1.80767,0.100394,0.00500011,1.1584 beta-lactamase_0_I280G,beta-lactamase_0_280,TEM-1,beta-lactamase_0,P62593,1.15841,NO,280,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.0500837,0.0530888,1.15841 beta-lactamase_0_G281F,beta-lactamase_0_281,TEM-1,beta-lactamase_0,P62593,1.15842,NO,281,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-2.247,,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.0500837,0.0406482,1.15842 beta-lactamase_0_G90Y,beta-lactamase_0_90,TEM-1,beta-lactamase_0,P62593,1.15843,NO,90,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-2.091,-4.355,2.264,,0.598,T,A,0.29,0.32,2.04,,77.62,HOB,-1.52633,0.0500837,0.00490273,1.15843 beta-lactamase_0_I285M,beta-lactamase_0_285,TEM-1,beta-lactamase_0,P62593,1.15864,NO,285,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.0500837,0.101555,1.15864 kka2_1:8_I2P,kka2_1:8_2,Kka2,kka2_1:8,P00552,1.15868,NO,2,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.787,-3.734,1.947,,,,,,,,,71.59,HHA,-1.92433,0.100394,0.00246644,1.15868 kka2_1:8_I2P,kka2_1:8_2,Kka2,kka2_1:8,P00552,1.15868,NO,2,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.787,-3.734,1.947,,,,,,,,,71.59,HHA,-1.92433,0.100394,0.00246644,1.15868 kka2_1:2_A35C,kka2_1:2_35,Kka2,kka2_1:2,P00552,1.15871,NO,35,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.127,-3.602,1.475,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.295029,0.00630016,1.15871 kka2_1:2_D23K,kka2_1:2_23,Kka2,kka2_1:2,P00552,1.15877,NO,23,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.459,-3.049,0.59,,0.695,E,B,0.75,-0.65,18.207,18.207,65.53,HAH,-1.94033,0.295029,0.007195,1.15877 kka2_1:8_Q4F,kka2_1:8_4,Kka2,kka2_1:8,P00552,1.15881,NO,4,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.361,-4.126,1.765,,,,,,,2.026,,71.59,APA,-1.95533,0.100394,0.00239179,1.15881 kka2_1:8_Q4F,kka2_1:8_4,Kka2,kka2_1:8,P00552,1.15881,NO,4,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.361,-4.126,1.765,,,,,,,2.026,,71.59,APA,-1.95533,0.100394,0.00239179,1.15881 beta-lactamase_0_T138D,beta-lactamase_0_138,TEM-1,beta-lactamase_0,P62593,1.15891,NO,138,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.506,-2.325,-0.181,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.0500837,0.00487868,1.15891 kka2_1:8_A168L,kka2_1:8_168,Kka2,kka2_1:8,P00552,1.15893,NO,168,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.989,-3.651,1.662,,0.67,H,A,0.46,0.15,11.329,11.329,64.39,OHA,-2.12933,0.100394,0.00806773,1.15893 kka2_1:8_A168L,kka2_1:8_168,Kka2,kka2_1:8,P00552,1.15893,NO,168,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.989,-3.651,1.662,,0.67,H,A,0.46,0.15,11.329,11.329,64.39,OHA,-2.12933,0.100394,0.00806773,1.15893 kka2_1:4_Q42Y,kka2_1:4_42,Kka2,kka2_1:4,P00552,1.159,NO,42,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.907,-4.454,1.547,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.168804,0.00679212,1.159 kka2_1:4_G164L,kka2_1:4_164,Kka2,kka2_1:4,P00552,1.15909,NO,164,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.869,-3.829,2.96,,0.862,T,l,0.75,1.45,1.539,,64.39,POH,-1.828,0.168804,0.00442091,1.15909 kka2_1:8_L152H,kka2_1:8_152,Kka2,kka2_1:8,P00552,1.15914,NO,152,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.521,-4.868,3.347,,0.547,.,A,0.55,1.36,1.442,,63.64,OHH,-1.162,0.100394,0.00674868,1.15914 kka2_1:8_L152H,kka2_1:8_152,Kka2,kka2_1:8,P00552,1.15914,NO,152,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.521,-4.868,3.347,,0.547,.,A,0.55,1.36,1.442,,63.64,OHH,-1.162,0.100394,0.00674868,1.15914 beta-lactamase_0_S201L,beta-lactamase_0_201,TEM-1,beta-lactamase_0,P62593,1.15926,NO,201,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.183,-2.615,1.432,,0.064,H,A,0.27,-0.07,3.54,,64.69,HPB,-1.451,0.0500837,0.00198815,1.15926 kka2_1:4_T28K,kka2_1:4_28,Kka2,kka2_1:4,P00552,1.15927,NO,28,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.883,-3.68,1.797,,0.353,S,B,0.82,2.02,4.415,,63.64,PPH,-1.74467,0.168804,0.00743084,1.15927 kka2_1:4_A255C,kka2_1:4_255,Kka2,kka2_1:4,P00552,1.15933,NO,255,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.715,-5.069,3.354,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.168804,0.0126809,1.15933 beta-lactamase_0_R41N,beta-lactamase_0_41,TEM-1,beta-lactamase_0,P62593,1.15937,NO,41,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-0.942,-3.445,2.503,,0.321,E,B,1.2,-0.07,2.68,,65.03,HBH,-1.30267,0.0500837,0.00123327,1.15937 gb1_V255R,gb1_255,gb1,gb1,P06654,1.15941,NO,255,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-3.127,-3.608,0.481,,,,,,,1.323,,45.54,BHH,-2.03867,0.177985,0.00408354,1.15941 kka2_1:4_F133Y,kka2_1:4_133,Kka2,kka2_1:4,P00552,1.15948,NO,133,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-0.871,-2.422,1.551,,0.178,.,B,0.58,0.43,0.786,,42.42,OHA,-0.871667,0.168804,0.00182168,1.15948 WW_domain_D170L,WW_domain_170,Yap65,WW_domain,P46937,1.15949,NO,170,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.213,-3.579,2.366,,,,,,,0.399,,15.87,OAH,-1.38,0.153962,0.00123319,1.15949 kka2_1:4_E235K,kka2_1:4_235,Kka2,kka2_1:4,P00552,1.15957,NO,235,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.955,-2.949,0.994,,0.631,H,A,1.04,0.12,23.175,23.175,65.53,OAH,-2.07267,0.168804,0.0102806,1.15957 kka2_1:8_W91F,kka2_1:8_91,Kka2,kka2_1:8,P00552,1.15962,NO,91,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-1.178,-2.297,1.119,,0.077,E,B,1.51,0.27,2.51,,48.48,AHH,-1.51,0.100394,0.00358653,1.15962 kka2_1:8_W91F,kka2_1:8_91,Kka2,kka2_1:8,P00552,1.15962,NO,91,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-1.178,-2.297,1.119,,0.077,E,B,1.51,0.27,2.51,,48.48,AHH,-1.51,0.100394,0.00358653,1.15962 beta-lactamase_0_P105R,beta-lactamase_0_105,TEM-1,beta-lactamase_0,P62593,1.15972,NO,105,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-0.813,-3.93,3.117,,0.226,T,A,0.52,0.8,3.48,,63.29,POH,-1.01533,0.0500837,0.0011981,1.15972 kka2_1:8_D101N,kka2_1:8_101,Kka2,kka2_1:8,P00552,1.15973,NO,101,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.028,-2.135,1.107,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.100394,0.00423361,1.15973 kka2_1:8_D101N,kka2_1:8_101,Kka2,kka2_1:8,P00552,1.15973,NO,101,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.028,-2.135,1.107,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.100394,0.00423361,1.15973 kka2_1:4_L57R,kka2_1:4_57,Kka2,kka2_1:4,P00552,1.15975,NO,57,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.898,-4.138,2.24,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.168804,0.00723769,1.15975 kka2_1:8_H8C,kka2_1:8_8,Kka2,kka2_1:8,P00552,1.15996,NO,8,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-2.759,-2.768,0.009,,,,,,,,,71.59,HBH,-2.25467,0.100394,0.00256422,1.15996 kka2_1:8_H8C,kka2_1:8_8,Kka2,kka2_1:8,P00552,1.15996,NO,8,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-2.759,-2.768,0.009,,,,,,,,,71.59,HBH,-2.25467,0.100394,0.00256422,1.15996 kka2_1:8_T28A,kka2_1:8_28,Kka2,kka2_1:8,P00552,1.15996,NO,28,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.883,-2.105,0.222,,0.353,S,B,0.22,2.02,18.114,18.114,63.64,PPH,-1.74467,0.100394,0.00743084,1.15996 kka2_1:8_T28A,kka2_1:8_28,Kka2,kka2_1:8,P00552,1.15996,NO,28,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.883,-2.105,0.222,,0.353,S,B,0.22,2.02,18.114,18.114,63.64,PPH,-1.74467,0.100394,0.00743084,1.15996 PSD95pdz3_H317C,PSD95pdz3_317,PSD95pdz3,PSD95pdz3,P31016,1.15997,NO,317,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-1.627,-4.769,3.142,6.19713,,,,,25.885,,,,HBB,-1.613,0.0758425,0.00111619,1.15997 kka2_1:2_R44Q,kka2_1:2_44,Kka2,kka2_1:2,P00552,1.16001,NO,44,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.062,-2.483,0.421,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.295029,0.00745043,1.16001 kka2_1:2_Q61A,kka2_1:2_61,Kka2,kka2_1:2,P00552,1.16003,NO,61,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.982,-1.987,-0.995,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.295029,0.00612092,1.16003 beta-lactamase_0_I93H,beta-lactamase_0_93,TEM-1,beta-lactamase_0,P62593,1.16008,NO,93,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.401,-5.004,3.603,,0.128,E,B,0.48,0.44,1.266,,67.83,BHB,-1.873,0.0500837,0.00527066,1.16008 kka2_1:2_S251P,kka2_1:2_251,Kka2,kka2_1:2,P00552,1.16011,NO,251,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.636,-2.034,-0.602,,0.712,H,A,0.27,-0.25,32.832,32.832,71.59,APP,-2.09367,0.295029,0.0138916,1.16011 beta-lactamase_0_E238R,beta-lactamase_0_238,TEM-1,beta-lactamase_0,P62593,1.16012,NO,238,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.002,-3.465,1.463,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.0500837,0.00743256,1.16012 kka2_1:4_I246S,kka2_1:4_246,Kka2,kka2_1:4,P00552,1.16034,NO,246,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-2.008,-3.645,1.637,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.168804,0.0139479,1.16034 kka2_1:4_S11G,kka2_1:4_11,Kka2,kka2_1:4,P00552,1.16034,NO,11,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.322,-3.427,1.105,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.168804,0.00381691,1.16034 kka2_1:8_Q155W,kka2_1:8_155,Kka2,kka2_1:8,P00552,1.16038,NO,155,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.606,-5.444,2.838,,0.525,T,A,0.64,1.49,,,63.64,APA,-1.726,0.100394,0.00641853,1.16038 kka2_1:8_Q155W,kka2_1:8_155,Kka2,kka2_1:8,P00552,1.16038,NO,155,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.606,-5.444,2.838,,0.525,T,A,0.64,1.49,,,63.64,APA,-1.726,0.100394,0.00641853,1.16038 kka2_1:8_S114W,kka2_1:8_114,Kka2,kka2_1:8,P00552,1.16042,NO,114,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.527,-5.559,3.032,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.100394,0.00705262,1.16042 kka2_1:8_S114W,kka2_1:8_114,Kka2,kka2_1:8,P00552,1.16042,NO,114,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.527,-5.559,3.032,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.100394,0.00705262,1.16042 kka2_1:4_A71G,kka2_1:4_71,Kka2,kka2_1:4,P00552,1.16054,NO,71,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.824,-2.399,0.575,,0.553,H,A,0.46,0.08,5.76,,64.39,HHP,-1.74033,0.168804,0.00727707,1.16054 kka2_1:2_Q27N,kka2_1:2_27,Kka2,kka2_1:2,P00552,1.1606,NO,27,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-1.659,-3.726,2.067,,0.608,.,A,0.64,0.71,0.521,,65.53,PPP,-1.90733,0.295029,0.00595365,1.1606 kka2_1:4_V46R,kka2_1:4_46,Kka2,kka2_1:4,P00552,1.16061,NO,46,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-2.62,-2.74,0.12,,0.192,.,B,0.44,-1.12,9.564,,92.05,OHH,-1.88633,0.168804,0.00631301,1.16061 beta-lactamase_0_E164I,beta-lactamase_0_164,TEM-1,beta-lactamase_0,P62593,1.16067,NO,164,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-0.948,-4.08,3.132,,0.011,T,B,1.04,-0.4,1.011,,64.69,HAO,-1.388,0.0500837,0.00137286,1.16067 beta-lactamase_0_T269I,beta-lactamase_0_269,TEM-1,beta-lactamase_0,P62593,1.16067,NO,269,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.0500837,0.00950944,1.16067 kka2_1:8_G43T,kka2_1:8_43,Kka2,kka2_1:8,P00552,1.16078,NO,43,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.587,-2.998,1.411,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.100394,0.0071925,1.16078 kka2_1:8_G43T,kka2_1:8_43,Kka2,kka2_1:8,P00552,1.16078,NO,43,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.587,-2.998,1.411,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.100394,0.0071925,1.16078 kka2_1:4_A237V,kka2_1:4_237,Kka2,kka2_1:4,P00552,1.16093,NO,237,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.12,-1.303,-0.817,,0.068,H,A,0.46,-0.71,2.444,,92.05,HHA,-2.10433,0.168804,0.012257,1.16093 beta-lactamase_0_Q267H,beta-lactamase_0_267,TEM-1,beta-lactamase_0,P62593,1.16094,NO,267,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.0500837,0.0102128,1.16094 kka2_1:2_K175T,kka2_1:2_175,Kka2,kka2_1:2,P00552,1.16096,NO,175,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-2.897,-2.9,0.003,,0.579,H,A,1.3,0.51,15.629,15.629,71.59,HBH,-1.82333,0.295029,0.00693093,1.16096 kka2_1:8_G95Q,kka2_1:8_95,Kka2,kka2_1:8,P00552,1.16096,NO,95,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-2.403,-2.902,0.499,,0.126,E,B,0.75,-0.74,7.774,,71.59,HOA,-2.198,0.100394,0.00743616,1.16096 kka2_1:8_G95Q,kka2_1:8_95,Kka2,kka2_1:8,P00552,1.16096,NO,95,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-2.403,-2.902,0.499,,0.126,E,B,0.75,-0.74,7.774,,71.59,HOA,-2.198,0.100394,0.00743616,1.16096 kka2_1:1_Q4E,kka2_1:1_4,Kka2,kka2_1:1,P00552,1.16097,NO,4,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.361,-3.058,0.697,,,,,,,5.615,,71.59,APA,-1.95533,0.520039,0.00239179,1.16097 kka2_1:8_D154V,kka2_1:8_154,Kka2,kka2_1:8,P00552,1.16111,NO,154,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.876,-3.815,2.939,,0.457,,b,0.29,1.48,0.844,,52.65,HAP,-1.52467,0.100394,0.00292633,1.16111 kka2_1:8_D154V,kka2_1:8_154,Kka2,kka2_1:8,P00552,1.16111,NO,154,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.876,-3.815,2.939,,0.457,,b,0.29,1.48,0.844,,52.65,HAP,-1.52467,0.100394,0.00292633,1.16111 beta-lactamase_0_D99T,beta-lactamase_0_99,TEM-1,beta-lactamase_0,P62593,1.16114,NO,99,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.191,-3.531,2.34,,0.402,G,A,0.75,0.36,0.374,,64.69,PAH,-1.794,0.0500837,0.00305446,1.16114 beta-lactamase_0_Q88S,beta-lactamase_0_88,TEM-1,beta-lactamase_0,P62593,1.16123,NO,88,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.086,-2.48,0.394,,0.807,,B,0.64,2.03,0.4,,77.62,APH,-1.53433,0.0500837,0.00504167,1.16123 kka2_1:8_E149T,kka2_1:8_149,Kka2,kka2_1:8,P00552,1.16123,NO,149,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.994,-3.656,1.662,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.100394,0.00803343,1.16123 kka2_1:8_E149T,kka2_1:8_149,Kka2,kka2_1:8,P00552,1.16123,NO,149,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.994,-3.656,1.662,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.100394,0.00803343,1.16123 kka2_1:8_A176G,kka2_1:8_176,Kka2,kka2_1:8,P00552,1.16124,NO,176,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.621,-3.323,1.702,,0.806,H,A,0.46,-0.03,18.904,18.904,65.53,BHB,-2.26667,0.100394,0.0083587,1.16124 kka2_1:8_A176G,kka2_1:8_176,Kka2,kka2_1:8,P00552,1.16124,NO,176,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.621,-3.323,1.702,,0.806,H,A,0.46,-0.03,18.904,18.904,65.53,BHB,-2.26667,0.100394,0.0083587,1.16124 kka2_1:8_I254L,kka2_1:8_254,Kka2,kka2_1:8,P00552,1.16129,NO,254,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.933,-1.561,-0.372,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.100394,0.0132375,1.16129 kka2_1:8_I254L,kka2_1:8_254,Kka2,kka2_1:8,P00552,1.16129,NO,254,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.933,-1.561,-0.372,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.100394,0.0132375,1.16129 kka2_1:8_A14K,kka2_1:8_14,Kka2,kka2_1:8,P00552,1.16138,NO,14,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.837,-2.596,0.759,,0.728,G,A,0.46,0.7,,,71.59,HHH,-1.82567,0.100394,0.00706614,1.16138 kka2_1:8_A14K,kka2_1:8_14,Kka2,kka2_1:8,P00552,1.16138,NO,14,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.837,-2.596,0.759,,0.728,G,A,0.46,0.7,,,71.59,HHH,-1.82567,0.100394,0.00706614,1.16138 kka2_1:2_F256Y,kka2_1:2_256,Kka2,kka2_1:2,P00552,1.16139,NO,256,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.49,-1.474,-0.016,,,H,A,0.58,-0.78,1.653,,53.03,HHH,-1.423,0.295029,0.0132841,1.16139 kka2_1:4_V16S,kka2_1:4_16,Kka2,kka2_1:4,P00552,1.16144,NO,16,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-3.087,-2.803,-0.284,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.168804,0.00694011,1.16144 kka2_1:4_D157G,kka2_1:4_157,Kka2,kka2_1:4,P00552,1.16147,NO,157,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.993,-2.513,1.52,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.168804,0.0042313,1.16147 kka2_1:4_D180G,kka2_1:4_180,Kka2,kka2_1:4,P00552,1.16147,NO,180,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.416,-2.606,0.19,,1.03,S,a,0.29,1.5,14.668,14.668,71.59,OAO,-2.02933,0.168804,0.00756412,1.16147 beta-lactamase_0_N152H,beta-lactamase_0_152,TEM-1,beta-lactamase_0,P62593,1.1615,NO,152,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-2.757,-3.372,0.615,,0.863,H,A,0.61,0.92,2.151,,77.62,BPH,-2.97,0.0500837,0.00471429,1.1615 kka2_1:8_V198C,kka2_1:8_198,Kka2,kka2_1:8,P00552,1.16152,NO,198,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.719,-4.752,3.033,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.100394,0.00835002,1.16152 kka2_1:8_V198C,kka2_1:8_198,Kka2,kka2_1:8,P00552,1.16152,NO,198,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.719,-4.752,3.033,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.100394,0.00835002,1.16152 kka2_1:8_E160D,kka2_1:8_160,Kka2,kka2_1:8,P00552,1.16156,NO,160,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.683,-1.462,-0.221,,0.989,G,A,1.04,2.28,2.164,,71.59,AAA,-1.36133,0.100394,0.00935762,1.16156 kka2_1:8_E160D,kka2_1:8_160,Kka2,kka2_1:8,P00552,1.16156,NO,160,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.683,-1.462,-0.221,,0.989,G,A,1.04,2.28,2.164,,71.59,AAA,-1.36133,0.100394,0.00935762,1.16156 kka2_1:4_T125C,kka2_1:4_125,Kka2,kka2_1:4,P00552,1.16165,NO,125,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.622,-5.084,2.462,,0.791,T,A,0.82,0.33,1.612,,92.05,BPH,-1.56933,0.168804,0.00821755,1.16165 kka2_1:8_M178V,kka2_1:8_178,Kka2,kka2_1:8,P00552,1.16173,NO,178,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-3.206,-2.808,-0.398,,0.554,,b,1.59,0.68,13.268,13.268,71.59,BHO,-2.154,0.100394,0.00717253,1.16173 kka2_1:8_M178V,kka2_1:8_178,Kka2,kka2_1:8,P00552,1.16173,NO,178,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-3.206,-2.808,-0.398,,0.554,,b,1.59,0.68,13.268,13.268,71.59,BHO,-2.154,0.100394,0.00717253,1.16173 kka2_1:2_R143Q,kka2_1:2_143,Kka2,kka2_1:2,P00552,1.16182,NO,143,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.525,-3.295,0.77,,0.325,H,A,0.16,1.22,14.853,14.853,65.53,ABH,-1.86833,0.295029,0.00662247,1.16182 kka2_1:8_T146R,kka2_1:8_146,Kka2,kka2_1:8,P00552,1.16186,NO,146,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.978,-2.581,-0.397,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.100394,0.00606474,1.16186 kka2_1:8_T146R,kka2_1:8_146,Kka2,kka2_1:8,P00552,1.16186,NO,146,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.978,-2.581,-0.397,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.100394,0.00606474,1.16186 kka2_1:8_L7I,kka2_1:8_7,Kka2,kka2_1:8,P00552,1.16187,NO,7,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.926,-3.353,1.427,,,,,,,,,71.59,OHB,-2.12333,0.100394,0.00269456,1.16187 kka2_1:8_L7I,kka2_1:8_7,Kka2,kka2_1:8,P00552,1.16187,NO,7,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.926,-3.353,1.427,,,,,,,,,71.59,OHB,-2.12333,0.100394,0.00269456,1.16187 kka2_1:8_A71G,kka2_1:8_71,Kka2,kka2_1:8,P00552,1.1619,NO,71,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.824,-2.399,0.575,,0.553,H,A,0.46,0.08,18.64,18.64,64.39,HHP,-1.74033,0.100394,0.00727707,1.1619 kka2_1:8_A71G,kka2_1:8_71,Kka2,kka2_1:8,P00552,1.1619,NO,71,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.824,-2.399,0.575,,0.553,H,A,0.46,0.08,18.64,18.64,64.39,HHP,-1.74033,0.100394,0.00727707,1.1619 beta-lactamase_0_R242K,beta-lactamase_0_242,TEM-1,beta-lactamase_0,P62593,1.16195,NO,242,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.0500837,0.00452879,1.16195 beta-lactamase_0_L248I,beta-lactamase_0_248,TEM-1,beta-lactamase_0,P62593,1.16209,NO,248,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.794,,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.0500837,0.00428493,1.16209 kka2_1:2_L165S,kka2_1:2_165,Kka2,kka2_1:2,P00552,1.16211,NO,165,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-2.453,-3.581,1.128,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.295029,0.00801161,1.16211 kka2_1:4_A110E,kka2_1:4_110,Kka2,kka2_1:4,P00552,1.16211,NO,110,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.064,-2.266,0.202,,0.175,H,A,0.46,-1.19,23.237,23.237,71.59,OHA,-1.91867,0.168804,0.00759851,1.16211 kka2_1:2_I221L,kka2_1:2_221,Kka2,kka2_1:2,P00552,1.16218,NO,221,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.739,-1.153,-0.586,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.295029,0.00945908,1.16218 beta-lactamase_0_Q88K,beta-lactamase_0_88,TEM-1,beta-lactamase_0,P62593,1.16219,NO,88,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.086,-2.839,0.753,,0.807,,B,0.64,2.03,0.4,,77.62,APH,-1.53433,0.0500837,0.00504167,1.16219 kka2_1:2_D180Q,kka2_1:2_180,Kka2,kka2_1:2,P00552,1.16221,NO,180,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.416,-3.007,0.591,,1.03,S,a,0.75,1.5,1.27,,71.59,OAO,-2.02933,0.295029,0.00756412,1.16221 kka2_1:4_C31K,kka2_1:4_31,Kka2,kka2_1:4,P00552,1.16223,NO,31,C,K,CK,Special,PositiveCharge,5.07,9.74,4.67,202,121,146,25,108.5,168.6,60.1,-2.246,-3.377,1.131,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.168804,0.00681582,1.16223 kka2_1:2_A172S,kka2_1:2_172,Kka2,kka2_1:2,P00552,1.16229,NO,172,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.757,-2.625,0.868,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.295029,0.0079265,1.16229 kka2_1:8_I29L,kka2_1:8_29,Kka2,kka2_1:8,P00552,1.16241,NO,29,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.692,-1.88,0.188,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.100394,0.00619521,1.16241 kka2_1:8_I29L,kka2_1:8_29,Kka2,kka2_1:8,P00552,1.16241,NO,29,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.692,-1.88,0.188,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.100394,0.00619521,1.16241 kka2_1:2_E3F,kka2_1:2_3,Kka2,kka2_1:2,P00552,1.16246,NO,3,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.199,-3.772,1.573,,,,,,,7.22,,92.05,HAP,-2.11567,0.295029,0.00267607,1.16246 kka2_1:8_K138Q,kka2_1:8_138,Kka2,kka2_1:8,P00552,1.16255,NO,138,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-2.5,-2.969,0.469,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.100394,0.00628542,1.16255 kka2_1:8_K138Q,kka2_1:8_138,Kka2,kka2_1:8,P00552,1.16255,NO,138,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-2.5,-2.969,0.469,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.100394,0.00628542,1.16255 beta-lactamase_0_T179A,beta-lactamase_0_179,TEM-1,beta-lactamase_0,P62593,1.16256,NO,179,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.085,-2.334,1.249,,,E,B,0.22,-1.38,0.367,,73.08,PPH,-1.557,0.0500837,0.00226045,1.16256 beta-lactamase_0_D212L,beta-lactamase_0_212,TEM-1,beta-lactamase_0,P62593,1.16263,NO,212,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.624,-3.598,1.974,,0.037,,b,0.75,-0.58,3.34,,74.48,HAB,-1.77667,0.0500837,0.00644302,1.16263 kka2_1:4_V80R,kka2_1:4_80,Kka2,kka2_1:4,P00552,1.16267,NO,80,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.144,-4.199,3.055,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.168804,0.00488211,1.16267 kka2_1:8_V83A,kka2_1:8_83,Kka2,kka2_1:8,P00552,1.16281,NO,83,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-2.567,-2.453,-0.114,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.100394,0.00650486,1.16281 kka2_1:8_V83A,kka2_1:8_83,Kka2,kka2_1:8,P00552,1.16281,NO,83,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-2.567,-2.453,-0.114,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.100394,0.00650486,1.16281 beta-lactamase_0_G194K,beta-lactamase_0_194,TEM-1,beta-lactamase_0,P62593,1.16287,NO,194,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.396,-3.557,2.161,,0.276,S,b,0.29,0.36,3.017,,67.83,POA,-1.832,0.0500837,0.00392163,1.16287 kka2_1:8_A150K,kka2_1:8_150,Kka2,kka2_1:8,P00552,1.16289,NO,150,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.949,-3.494,2.545,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.100394,0.0045009,1.16289 kka2_1:8_A150K,kka2_1:8_150,Kka2,kka2_1:8,P00552,1.16289,NO,150,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.949,-3.494,2.545,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.100394,0.0045009,1.16289 PSD95pdz3_H317W,PSD95pdz3_317,PSD95pdz3,PSD95pdz3,P31016,1.16294,NO,317,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-1.627,-4.779,3.152,6.19713,,,,,25.885,,,,HBB,-1.613,0.0758425,0.00111619,1.16294 beta-lactamase_0_S283M,beta-lactamase_0_283,TEM-1,beta-lactamase_0,P62593,1.16296,NO,283,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.0500837,0.0429138,1.16296 beta-lactamase_0_E62I,beta-lactamase_0_62,TEM-1,beta-lactamase_0,P62593,1.16301,NO,62,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.193,-4.086,2.893,,0.342,S,B,1.04,-0.3,5.784,,73.08,AAB,-1.417,0.0500837,0.00264802,1.16301 kka2_1:8_A87H,kka2_1:8_87,Kka2,kka2_1:8,P00552,1.16305,NO,87,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.917,-3.188,1.271,,1.039,S,L,0.46,1.57,16.115,16.115,65.53,AHO,-1.822,0.100394,0.00791281,1.16305 kka2_1:8_A87H,kka2_1:8_87,Kka2,kka2_1:8,P00552,1.16305,NO,87,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.917,-3.188,1.271,,1.039,S,L,0.46,1.57,16.115,16.115,65.53,AHO,-1.822,0.100394,0.00791281,1.16305 kka2_1:8_V84M,kka2_1:8_84,Kka2,kka2_1:8,P00552,1.16307,NO,84,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-2.279,-4.623,2.344,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.100394,0.00724019,1.16307 kka2_1:8_V84M,kka2_1:8_84,Kka2,kka2_1:8,P00552,1.16307,NO,84,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-2.279,-4.623,2.344,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.100394,0.00724019,1.16307 kka2_1:8_R253N,kka2_1:8_253,Kka2,kka2_1:8,P00552,1.16315,NO,253,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.356,-3.661,2.305,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.100394,0.0144195,1.16315 kka2_1:8_R253N,kka2_1:8_253,Kka2,kka2_1:8,P00552,1.16315,NO,253,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.356,-3.661,2.305,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.100394,0.0144195,1.16315 kka2_1:4_R202A,kka2_1:4_202,Kka2,kka2_1:4,P00552,1.16327,NO,202,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.761,-2.662,0.901,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.168804,0.00696498,1.16327 kka2_1:8_P76M,kka2_1:8_76,Kka2,kka2_1:8,P00552,1.1633,NO,76,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.449,-4.717,3.268,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.100394,0.00625685,1.1633 kka2_1:8_P76M,kka2_1:8_76,Kka2,kka2_1:8,P00552,1.1633,NO,76,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.449,-4.717,3.268,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.100394,0.00625685,1.1633 kka2_1:4_L260M,kka2_1:4_260,Kka2,kka2_1:4,P00552,1.16333,NO,260,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.741,-3.833,3.092,,0.022,H,A,0.55,-0.52,,,,HHA,-0.845667,0.168804,0.0233782,1.16333 kka2_1:2_G181F,kka2_1:2_181,Kka2,kka2_1:2,P00552,1.16335,NO,181,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-2.698,-4.379,1.681,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.295029,0.00728319,1.16335 kka2_1:8_D62E,kka2_1:8_62,Kka2,kka2_1:8,P00552,1.16341,NO,62,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.591,-2.795,1.204,,0.262,H,A,0.29,0.08,5.58,,64.39,PAA,-1.77833,0.100394,0.00744243,1.16341 kka2_1:8_D62E,kka2_1:8_62,Kka2,kka2_1:8,P00552,1.16341,NO,62,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.591,-2.795,1.204,,0.262,H,A,0.29,0.08,5.58,,64.39,PAA,-1.77833,0.100394,0.00744243,1.16341 beta-lactamase_0_H110G,beta-lactamase_0_110,TEM-1,beta-lactamase_0,P62593,1.16357,NO,110,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-1.706,-3.573,1.867,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.0500837,0.00441499,1.16357 beta-lactamase_0_K30S,beta-lactamase_0_30,TEM-1,beta-lactamase_0,P62593,1.16358,NO,30,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-2.307,-3.277,0.97,,0.142,H,A,2.34,-0.65,1.491,,93.01,HBH,-2.32833,0.0500837,0.00448593,1.16358 kka2_1:4_H106Y,kka2_1:4_106,Kka2,kka2_1:4,P00552,1.16373,NO,106,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-3.13,-4.391,1.261,,1.065,.,a,0.17,-0.95,16.74,16.74,71.59,PBH,-2.10433,0.168804,0.00730778,1.16373 kka2_1:8_G55T,kka2_1:8_55,Kka2,kka2_1:8,P00552,1.16375,NO,55,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.625,-3.642,2.017,,0.517,S,b,0.29,1.19,8.881,,63.64,POH,-2.05967,0.100394,0.00667877,1.16375 kka2_1:8_G55T,kka2_1:8_55,Kka2,kka2_1:8,P00552,1.16375,NO,55,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.625,-3.642,2.017,,0.517,S,b,0.29,1.19,8.881,,63.64,POH,-2.05967,0.100394,0.00667877,1.16375 kka2_1:8_E111D,kka2_1:8_111,Kka2,kka2_1:8,P00552,1.16376,NO,111,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.28,-2.742,0.462,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.100394,0.00746789,1.16376 kka2_1:8_E111D,kka2_1:8_111,Kka2,kka2_1:8,P00552,1.16376,NO,111,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.28,-2.742,0.462,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.100394,0.00746789,1.16376 kka2_1:8_Q252H,kka2_1:8_252,Kka2,kka2_1:8,P00552,1.16381,NO,252,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.63,-3.494,0.864,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.100394,0.0121001,1.16381 kka2_1:8_Q252H,kka2_1:8_252,Kka2,kka2_1:8,P00552,1.16381,NO,252,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.63,-3.494,0.864,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.100394,0.0121001,1.16381 kka2_1:4_G95N,kka2_1:4_95,Kka2,kka2_1:4,P00552,1.16384,NO,95,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-2.403,-2.561,0.158,,0.126,E,B,0.29,-0.74,0.359,,71.59,HOA,-2.198,0.168804,0.00743616,1.16384 kka2_1:8_G164Q,kka2_1:8_164,Kka2,kka2_1:8,P00552,1.16384,NO,164,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.869,-4.074,3.205,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.100394,0.00442091,1.16384 kka2_1:8_G164Q,kka2_1:8_164,Kka2,kka2_1:8,P00552,1.16384,NO,164,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.869,-4.074,3.205,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.100394,0.00442091,1.16384 kka2_1:4_D180H,kka2_1:4_180,Kka2,kka2_1:4,P00552,1.16387,NO,180,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.416,-3.405,0.989,,1.03,S,a,0.29,1.5,14.668,14.668,71.59,OAO,-2.02933,0.168804,0.00756412,1.16387 kka2_1:8_A13R,kka2_1:8_13,Kka2,kka2_1:8,P00552,1.16387,NO,13,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.248,-2.994,0.746,,0.689,G,A,1.04,0.99,14.966,14.966,92.05,OHH,-1.646,0.100394,0.00784241,1.16387 kka2_1:8_A13R,kka2_1:8_13,Kka2,kka2_1:8,P00552,1.16387,NO,13,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.248,-2.994,0.746,,0.689,G,A,1.04,0.99,14.966,14.966,92.05,OHH,-1.646,0.100394,0.00784241,1.16387 kka2_1:8_T28Q,kka2_1:8_28,Kka2,kka2_1:8,P00552,1.1639,NO,28,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.883,-4.073,2.19,,0.353,S,B,0.22,2.02,18.114,18.114,63.64,PPH,-1.74467,0.100394,0.00743084,1.1639 kka2_1:8_T28Q,kka2_1:8_28,Kka2,kka2_1:8,P00552,1.1639,NO,28,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.883,-4.073,2.19,,0.353,S,B,0.22,2.02,18.114,18.114,63.64,PPH,-1.74467,0.100394,0.00743084,1.1639 kka2_1:2_I2E,kka2_1:2_2,Kka2,kka2_1:2,P00552,1.16397,NO,2,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.787,-3.519,1.732,,,,,,,5.773,,71.59,HHA,-1.92433,0.295029,0.00246644,1.16397 kka2_1:4_R147N,kka2_1:4_147,Kka2,kka2_1:4,P00552,1.16405,NO,147,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.123,-2.501,1.378,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.168804,0.00549168,1.16405 kka2_1:8_V83Q,kka2_1:8_83,Kka2,kka2_1:8,P00552,1.16408,NO,83,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-2.567,-3.072,0.505,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.100394,0.00650486,1.16408 kka2_1:8_V83Q,kka2_1:8_83,Kka2,kka2_1:8,P00552,1.16408,NO,83,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-2.567,-3.072,0.505,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.100394,0.00650486,1.16408 kka2_1:4_P167V,kka2_1:4_167,Kka2,kka2_1:4,P00552,1.1641,NO,167,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-2.403,-2.424,0.021,,0.18,H,A,0.52,0.75,3.6,,64.39,HOH,-2.26633,0.168804,0.00543203,1.1641 beta-lactamase_0_E102Y,beta-lactamase_0_102,TEM-1,beta-lactamase_0,P62593,1.16411,NO,102,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.118,-4.321,2.203,,0.722,S,B,1.04,1.82,4.773,,73.08,HAH,-1.581,0.0500837,0.00486633,1.16411 kka2_1:4_D118H,kka2_1:4_118,Kka2,kka2_1:4,P00552,1.16423,NO,118,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.07,-3.064,0.994,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.168804,0.0067852,1.16423 kka2_1:8_S68F,kka2_1:8_68,Kka2,kka2_1:8,P00552,1.16425,NO,68,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.623,-4.425,1.802,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.100394,0.00608265,1.16425 kka2_1:8_S68F,kka2_1:8_68,Kka2,kka2_1:8,P00552,1.16425,NO,68,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.623,-4.425,1.802,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.100394,0.00608265,1.16425 beta-lactamase_0_C75A,beta-lactamase_0_75,TEM-1,beta-lactamase_0,P62593,1.16437,NO,75,C,A,CA,Special,Hydrophobic,5.07,6,0.93,195,121,89,-32,108.5,88.6,-19.9,-1.245,-1.87,0.625,,,H,A,0.46,-0.87,2.256,,50,HOO,-1.24333,0.0500837,0.0034616,1.16437 beta-lactamase_0_T179L,beta-lactamase_0_179,TEM-1,beta-lactamase_0,P62593,1.1644,NO,179,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.085,-3.263,2.178,,,E,B,0.22,-1.38,0.367,,73.08,PPH,-1.557,0.0500837,0.00226045,1.1644 kka2_1:8_G74T,kka2_1:8_74,Kka2,kka2_1:8,P00552,1.1644,NO,74,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.18,-3.624,2.444,,0.621,T,l,0.29,0.2,2.014,,64.39,POH,-1.91667,0.100394,0.00587035,1.1644 kka2_1:8_G74T,kka2_1:8_74,Kka2,kka2_1:8,P00552,1.1644,NO,74,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.18,-3.624,2.444,,0.621,T,l,0.29,0.2,2.014,,64.39,POH,-1.91667,0.100394,0.00587035,1.1644 beta-lactamase_0_L191M,beta-lactamase_0_191,TEM-1,beta-lactamase_0,P62593,1.16447,NO,191,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.087,-4.016,2.929,,,H,A,0.55,0.09,12.255,12.255,63.29,BHH,-1.445,0.0500837,0.00263549,1.16447 kka2_1:4_Q155S,kka2_1:4_155,Kka2,kka2_1:4,P00552,1.16448,NO,155,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.606,-3.295,0.689,,0.525,T,A,0.64,1.49,1.592,,63.64,APA,-1.726,0.168804,0.00641853,1.16448 kka2_1:4_E86Y,kka2_1:4_86,Kka2,kka2_1:4,P00552,1.1645,NO,86,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.86,-2.948,1.088,,0.369,.,B,1.04,1.92,4.451,,63.26,PAH,-1.98067,0.168804,0.00642858,1.1645 kka2_1:2_Q252W,kka2_1:2_252,Kka2,kka2_1:2,P00552,1.16456,NO,252,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.63,-5.559,2.929,,0.906,H,A,0.64,0.35,5.613,,92.05,PPB,-2.20733,0.295029,0.0121001,1.16456 kka2_1:4_K175G,kka2_1:4_175,Kka2,kka2_1:4,P00552,1.16457,NO,175,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-2.897,-3.762,0.865,,0.579,H,A,1.3,0.51,15.629,15.629,71.59,HBH,-1.82333,0.168804,0.00693093,1.16457 kka2_1:4_L152I,kka2_1:4_152,Kka2,kka2_1:4,P00552,1.16457,NO,152,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.521,-2.522,1.001,,0.547,,A,1.59,1.36,2.318,,63.64,OHH,-1.162,0.168804,0.00674868,1.16457 beta-lactamase_0_L196S,beta-lactamase_0_196,TEM-1,beta-lactamase_0,P62593,1.1646,NO,196,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-2.478,-2.752,0.274,,0.518,S,A,0.55,1.35,6.513,6.513,77.62,AHH,-1.839,0.0500837,0.00512144,1.1646 beta-lactamase_0_I245L,beta-lactamase_0_245,TEM-1,beta-lactamase_0,P62593,1.16471,NO,245,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.0500837,0.00391032,1.16471 beta-lactamase_0_T131S,beta-lactamase_0_131,TEM-1,beta-lactamase_0,P62593,1.16477,NO,131,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.328,-1.912,0.584,,,H,A,0.22,-0.69,3.306,,67.48,PPH,-1.00867,0.0500837,0.00345886,1.16477 kka2_1:8_F20E,kka2_1:8_20,Kka2,kka2_1:8,P00552,1.16479,NO,20,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-3.354,-2.8,-0.554,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.100394,0.00701744,1.16479 kka2_1:8_F20E,kka2_1:8_20,Kka2,kka2_1:8,P00552,1.16479,NO,20,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-3.354,-2.8,-0.554,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.100394,0.00701744,1.16479 kka2_1:2_Q26A,kka2_1:2_26,Kka2,kka2_1:2,P00552,1.16482,NO,26,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.18,-2.361,0.181,,0.448,E,B,0.4,0.44,5.022,,92.05,HPP,-2.11167,0.295029,0.00708962,1.16482 kka2_1:8_V84I,kka2_1:8_84,Kka2,kka2_1:8,P00552,1.16485,NO,84,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-2.279,-2.844,0.565,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.100394,0.00724019,1.16485 kka2_1:8_V84I,kka2_1:8_84,Kka2,kka2_1:8,P00552,1.16485,NO,84,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-2.279,-2.844,0.565,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.100394,0.00724019,1.16485 PSD95pdz3_P311N,PSD95pdz3_311,PSD95pdz3,PSD95pdz3,P31016,1.16491,NO,311,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.236,-3.58,2.344,5.76649,,,,,14.78,,,,OOB,-1.409,0.0758425,0.0030796,1.16491 kka2_1:8_E3H,kka2_1:8_3,Kka2,kka2_1:8,P00552,1.16493,NO,3,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.199,-4.214,2.015,,,,,,,7.22,,92.05,HAP,-2.11567,0.100394,0.00267607,1.16493 kka2_1:8_E3H,kka2_1:8_3,Kka2,kka2_1:8,P00552,1.16493,NO,3,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.199,-4.214,2.015,,,,,,,7.22,,92.05,HAP,-2.11567,0.100394,0.00267607,1.16493 kka2_1:2_G95Q,kka2_1:2_95,Kka2,kka2_1:2,P00552,1.16496,NO,95,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-2.403,-2.902,0.499,,0.126,E,B,0.29,-0.74,0.359,,71.59,HOA,-2.198,0.295029,0.00743616,1.16496 kka2_1:8_S68T,kka2_1:8_68,Kka2,kka2_1:8,P00552,1.16519,NO,68,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.623,-3.655,1.032,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.100394,0.00608265,1.16519 kka2_1:8_S68T,kka2_1:8_68,Kka2,kka2_1:8,P00552,1.16519,NO,68,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.623,-3.655,1.032,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.100394,0.00608265,1.16519 gb1_D273R,gb1_273,gb1,gb1,P06654,1.16539,NO,273,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.998,-3.566,1.568,,,,,,,3.514,3.514,37.28,AAH,-1.72767,0.177985,0.00318903,1.16539 kka2_1:8_G95H,kka2_1:8_95,Kka2,kka2_1:8,P00552,1.1654,NO,95,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-2.403,-4.673,2.27,,0.126,E,B,0.75,-0.74,7.774,,71.59,HOA,-2.198,0.100394,0.00743616,1.1654 kka2_1:8_G95H,kka2_1:8_95,Kka2,kka2_1:8,P00552,1.1654,NO,95,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-2.403,-4.673,2.27,,0.126,E,B,0.75,-0.74,7.774,,71.59,HOA,-2.198,0.100394,0.00743616,1.1654 beta-lactamase_0_P217Y,beta-lactamase_0_217,TEM-1,beta-lactamase_0,P62593,1.16544,NO,217,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-2.062,-4.376,2.314,,0.496,I,A,0.52,-0.33,1.087,,74.48,OOH,-1.64333,0.0500837,0.00463211,1.16544 beta-lactamase_0_Q88G,beta-lactamase_0_88,TEM-1,beta-lactamase_0,P62593,1.16549,NO,88,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.086,-3.448,1.362,,0.807,,B,0.64,2.03,0.4,,77.62,APH,-1.53433,0.0500837,0.00504167,1.16549 kka2_1:4_D127R,kka2_1:4_127,Kka2,kka2_1:4,P00552,1.1655,NO,127,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.364,-3.039,1.675,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.168804,0.00660501,1.1655 kka2_1:8_A65L,kka2_1:8_65,Kka2,kka2_1:8,P00552,1.1655,NO,65,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.744,-2.62,0.876,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.100394,0.00709258,1.1655 kka2_1:8_A65L,kka2_1:8_65,Kka2,kka2_1:8,P00552,1.1655,NO,65,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.744,-2.62,0.876,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.100394,0.00709258,1.1655 kka2_1:8_L93I,kka2_1:8_93,Kka2,kka2_1:8,P00552,1.16553,NO,93,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.815,-3.008,2.193,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.100394,0.00131498,1.16553 kka2_1:8_L93I,kka2_1:8_93,Kka2,kka2_1:8,P00552,1.16553,NO,93,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.815,-3.008,2.193,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.100394,0.00131498,1.16553 kka2_1:8_L53V,kka2_1:8_53,Kka2,kka2_1:8,P00552,1.16554,NO,53,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-2.681,-2.592,-0.089,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.100394,0.00671168,1.16554 kka2_1:8_L53V,kka2_1:8_53,Kka2,kka2_1:8,P00552,1.16554,NO,53,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-2.681,-2.592,-0.089,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.100394,0.00671168,1.16554 beta-lactamase_0_G243E,beta-lactamase_0_243,TEM-1,beta-lactamase_0,P62593,1.16556,NO,243,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.0500837,0.00464034,1.16556 kka2_1:4_P98V,kka2_1:4_98,Kka2,kka2_1:4,P00552,1.16559,NO,98,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.526,-3.691,2.165,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.168804,0.00622754,1.16559 kka2_1:8_G181N,kka2_1:8_181,Kka2,kka2_1:8,P00552,1.16563,NO,181,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-2.698,-3.022,0.324,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.100394,0.00728319,1.16563 kka2_1:8_G181N,kka2_1:8_181,Kka2,kka2_1:8,P00552,1.16563,NO,181,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-2.698,-3.022,0.324,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.100394,0.00728319,1.16563 kka2_1:2_E149T,kka2_1:2_149,Kka2,kka2_1:2,P00552,1.16564,NO,149,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.994,-3.656,1.662,,0.674,H,A,1.04,1.63,15.361,15.361,71.59,HAH,-1.59667,0.295029,0.00803343,1.16564 kka2_1:4_E160C,kka2_1:4_160,Kka2,kka2_1:4,P00552,1.16564,NO,160,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.683,-5.219,3.536,,0.989,G,A,1.04,2.28,2.531,,71.59,AAA,-1.36133,0.168804,0.00935762,1.16564 gb1_A250Q,gb1_250,gb1,gb1,P06654,1.16568,NO,250,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.713,-3.357,1.644,,,,,,,3.465,,45.54,HHP,-1.74867,0.177985,0.00332003,1.16568 kka2_1:8_E3L,kka2_1:8_3,Kka2,kka2_1:8,P00552,1.16569,NO,3,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.199,-3.455,1.256,,,,,,,7.22,,92.05,HAP,-2.11567,0.100394,0.00267607,1.16569 kka2_1:8_E3L,kka2_1:8_3,Kka2,kka2_1:8,P00552,1.16569,NO,3,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.199,-3.455,1.256,,,,,,,7.22,,92.05,HAP,-2.11567,0.100394,0.00267607,1.16569 kka2_1:8_P249S,kka2_1:8_249,Kka2,kka2_1:8,P00552,1.16574,NO,249,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.867,-3.595,1.728,,0.406,.,B,0.52,-0.01,1.699,,92.05,HOA,-1.66867,0.100394,0.011045,1.16574 kka2_1:8_P249S,kka2_1:8_249,Kka2,kka2_1:8,P00552,1.16574,NO,249,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.867,-3.595,1.728,,0.406,.,B,0.52,-0.01,1.699,,92.05,HOA,-1.66867,0.100394,0.011045,1.16574 kka2_1:8_E149H,kka2_1:8_149,Kka2,kka2_1:8,P00552,1.16576,NO,149,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.994,-3.508,1.514,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.100394,0.00803343,1.16576 kka2_1:8_E149H,kka2_1:8_149,Kka2,kka2_1:8,P00552,1.16576,NO,149,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.994,-3.508,1.514,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.100394,0.00803343,1.16576 kka2_1:8_D5G,kka2_1:8_5,Kka2,kka2_1:8,P00552,1.16584,NO,5,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.306,-3.014,1.708,,,,,,,1.147,,71.59,PAO,-1.784,0.100394,0.00222864,1.16584 kka2_1:8_D5G,kka2_1:8_5,Kka2,kka2_1:8,P00552,1.16584,NO,5,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.306,-3.014,1.708,,,,,,,1.147,,71.59,PAO,-1.784,0.100394,0.00222864,1.16584 kka2_1:8_R177N,kka2_1:8_177,Kka2,kka2_1:8,P00552,1.16588,NO,177,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.282,-2.629,0.347,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.100394,0.00768224,1.16588 kka2_1:8_R177N,kka2_1:8_177,Kka2,kka2_1:8,P00552,1.16588,NO,177,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.282,-2.629,0.347,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.100394,0.00768224,1.16588 kka2_1:4_Q42R,kka2_1:4_42,Kka2,kka2_1:4,P00552,1.16589,NO,42,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.907,-3.056,0.149,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.168804,0.00679212,1.16589 kka2_1:8_R145K,kka2_1:8_145,Kka2,kka2_1:8,P00552,1.16596,NO,145,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.804,-2.124,0.32,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.100394,0.00846663,1.16596 kka2_1:8_R145K,kka2_1:8_145,Kka2,kka2_1:8,P00552,1.16596,NO,145,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.804,-2.124,0.32,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.100394,0.00846663,1.16596 beta-lactamase_0_G253K,beta-lactamase_0_253,TEM-1,beta-lactamase_0,P62593,1.16607,NO,253,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.0500837,0.00786358,1.16607 beta-lactamase_0_S283V,beta-lactamase_0_283,TEM-1,beta-lactamase_0,P62593,1.16613,NO,283,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.0500837,0.0429138,1.16613 kka2_1:8_D5A,kka2_1:8_5,Kka2,kka2_1:8,P00552,1.16622,NO,5,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.306,-3.033,1.727,,,,,,,1.147,,71.59,PAO,-1.784,0.100394,0.00222864,1.16622 kka2_1:8_D5A,kka2_1:8_5,Kka2,kka2_1:8,P00552,1.16622,NO,5,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.306,-3.033,1.727,,,,,,,1.147,,71.59,PAO,-1.784,0.100394,0.00222864,1.16622 kka2_1:8_C77G,kka2_1:8_77,Kka2,kka2_1:8,P00552,1.16628,NO,77,C,G,CG,Special,Special,5.07,3.29388,-1.77612,159,121,75,-46,108.5,60.1,-48.4,-1.477,-2.097,0.62,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.100394,0.00441216,1.16628 kka2_1:8_C77G,kka2_1:8_77,Kka2,kka2_1:8,P00552,1.16628,NO,77,C,G,CG,Special,Special,5.07,3.29388,-1.77612,159,121,75,-46,108.5,60.1,-48.4,-1.477,-2.097,0.62,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.100394,0.00441216,1.16628 beta-lactamase_0_T138A,beta-lactamase_0_138,TEM-1,beta-lactamase_0,P62593,1.16634,NO,138,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.506,-2.248,-0.258,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.0500837,0.00487868,1.16634 kka2_1:8_D33S,kka2_1:8_33,Kka2,kka2_1:8,P00552,1.16634,NO,33,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.186,-2.451,0.265,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.100394,0.00633568,1.16634 kka2_1:8_D33S,kka2_1:8_33,Kka2,kka2_1:8,P00552,1.16634,NO,33,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.186,-2.451,0.265,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.100394,0.00633568,1.16634 kka2_1:8_E96G,kka2_1:8_96,Kka2,kka2_1:8,P00552,1.16639,NO,96,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.573,-2.57,-0.003,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.100394,0.00369441,1.16639 kka2_1:8_E96G,kka2_1:8_96,Kka2,kka2_1:8,P00552,1.16639,NO,96,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.573,-2.57,-0.003,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.100394,0.00369441,1.16639 beta-lactamase_0_G249I,beta-lactamase_0_249,TEM-1,beta-lactamase_0,P62593,1.1664,NO,249,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.312,,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.0500837,0.00220169,1.1664 kka2_1:2_E111T,kka2_1:2_111,Kka2,kka2_1:2,P00552,1.16644,NO,111,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.28,-2.755,0.475,,0.155,H,A,1.52,-1.14,2.792,,65.53,HAB,-2.27833,0.295029,0.00746789,1.16644 beta-lactamase_0_A215Q,beta-lactamase_0_215,TEM-1,beta-lactamase_0,P62593,1.16648,NO,215,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.503,-2.998,1.495,,,,a,0.46,-0.93,0.494,,74.48,HHO,-1.42633,0.0500837,0.00544007,1.16648 kka2_1:8_E149Q,kka2_1:8_149,Kka2,kka2_1:8,P00552,1.16648,NO,149,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.994,-2.493,0.499,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.100394,0.00803343,1.16648 kka2_1:8_E149Q,kka2_1:8_149,Kka2,kka2_1:8,P00552,1.16648,NO,149,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.994,-2.493,0.499,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.100394,0.00803343,1.16648 beta-lactamase_0_C121Y,beta-lactamase_0_121,TEM-1,beta-lactamase_0,P62593,1.16652,NO,121,C,Y,CY,Special,Hydrophobic,5.07,5.66,0.59,194,121,181,60,108.5,193.6,85.1,-0.953,-4.188,3.235,,,H,A,0.46,-0.81,3.302,,63.29,HOP,-1.46767,0.0500837,0.000744322,1.16652 kka2_1:8_G74D,kka2_1:8_74,Kka2,kka2_1:8,P00552,1.16655,NO,74,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.18,-1.88,0.7,,0.621,T,l,0.29,0.2,2.014,,64.39,POH,-1.91667,0.100394,0.00587035,1.16655 kka2_1:8_G74D,kka2_1:8_74,Kka2,kka2_1:8,P00552,1.16655,NO,74,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.18,-1.88,0.7,,0.621,T,l,0.29,0.2,2.014,,64.39,POH,-1.91667,0.100394,0.00587035,1.16655 kka2_1:8_H139T,kka2_1:8_139,Kka2,kka2_1:8,P00552,1.16655,NO,139,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-2.809,-2.706,-0.103,,0.471,H,A,0.17,0.68,28.583,28.583,63.64,BBB,-2.22,0.100394,0.00734779,1.16655 kka2_1:8_H139T,kka2_1:8_139,Kka2,kka2_1:8,P00552,1.16655,NO,139,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-2.809,-2.706,-0.103,,0.471,H,A,0.17,0.68,28.583,28.583,63.64,BBB,-2.22,0.100394,0.00734779,1.16655 beta-lactamase_0_Q203R,beta-lactamase_0_203,TEM-1,beta-lactamase_0,P62593,1.16658,NO,203,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.168,-2.451,0.283,,0.47,H,A,0.64,-0.38,14.541,14.541,65.38,BPP,-1.614,0.0500837,0.00631514,1.16658 kka2_1:8_Q27T,kka2_1:8_27,Kka2,kka2_1:8,P00552,1.16658,NO,27,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-1.659,-3.598,1.939,,0.608,.,A,0.64,0.71,3.919,,65.53,PPP,-1.90733,0.100394,0.00595365,1.16658 kka2_1:8_Q27T,kka2_1:8_27,Kka2,kka2_1:8,P00552,1.16658,NO,27,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-1.659,-3.598,1.939,,0.608,.,A,0.64,0.71,3.919,,65.53,PPP,-1.90733,0.100394,0.00595365,1.16658 kka2_1:4_L53Y,kka2_1:4_53,Kka2,kka2_1:4,P00552,1.16659,NO,53,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-2.681,-4.449,1.768,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.168804,0.00671168,1.16659 kka2_1:8_I246K,kka2_1:8_246,Kka2,kka2_1:8,P00552,1.16659,NO,246,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-2.008,-3.871,1.863,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.100394,0.0139479,1.16659 kka2_1:8_I246K,kka2_1:8_246,Kka2,kka2_1:8,P00552,1.16659,NO,246,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-2.008,-3.871,1.863,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.100394,0.0139479,1.16659 kka2_1:8_L243C,kka2_1:8_243,Kka2,kka2_1:8,P00552,1.1666,NO,243,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-2.651,-2.68,0.029,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.100394,0.00884927,1.1666 kka2_1:8_L243C,kka2_1:8_243,Kka2,kka2_1:8,P00552,1.1666,NO,243,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-2.651,-2.68,0.029,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.100394,0.00884927,1.1666 kka2_1:8_Q27M,kka2_1:8_27,Kka2,kka2_1:8,P00552,1.16667,NO,27,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-1.659,-3.318,1.659,,0.608,.,A,0.64,0.71,3.919,,65.53,PPP,-1.90733,0.100394,0.00595365,1.16667 kka2_1:8_Q27M,kka2_1:8_27,Kka2,kka2_1:8,P00552,1.16667,NO,27,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-1.659,-3.318,1.659,,0.608,.,A,0.64,0.71,3.919,,65.53,PPP,-1.90733,0.100394,0.00595365,1.16667 WW_domain_D194A,WW_domain_194,Yap65,WW_domain,P46937,1.16677,NO,194,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.536,-3.148,1.612,5.95614,,,,,,1.948,,74.4,HAP,-1.78933,0.153962,0.00483742,1.16677 kka2_1:8_R18H,kka2_1:8_18,Kka2,kka2_1:8,P00552,1.16687,NO,18,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.055,-3.59,1.535,,0.474,T,A,1.2,0.54,19.629,19.629,71.59,ABH,-1.821,0.100394,0.00724065,1.16687 kka2_1:8_R18H,kka2_1:8_18,Kka2,kka2_1:8,P00552,1.16687,NO,18,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.055,-3.59,1.535,,0.474,T,A,1.2,0.54,19.629,19.629,71.59,ABH,-1.821,0.100394,0.00724065,1.16687 kka2_1:4_G55D,kka2_1:4_55,Kka2,kka2_1:4,P00552,1.16691,NO,55,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.625,-2.304,0.679,,0.517,S,b,0.75,1.19,15.753,15.753,63.64,POH,-2.05967,0.168804,0.00667877,1.16691 kka2_1:8_D23M,kka2_1:8_23,Kka2,kka2_1:8,P00552,1.16692,NO,23,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.459,-4.807,2.348,,0.695,E,B,0.75,-0.65,,,65.53,HAH,-1.94033,0.100394,0.007195,1.16692 kka2_1:8_D23M,kka2_1:8_23,Kka2,kka2_1:8,P00552,1.16692,NO,23,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.459,-4.807,2.348,,0.695,E,B,0.75,-0.65,,,65.53,HAH,-1.94033,0.100394,0.007195,1.16692 beta-lactamase_0_R189N,beta-lactamase_0_189,TEM-1,beta-lactamase_0,P62593,1.16701,NO,189,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.844,-3.633,1.789,,0.278,H,A,1.2,1.01,12.11,12.11,72.73,HBB,-1.668,0.0500837,0.0050699,1.16701 kka2_1:4_A87T,kka2_1:4_87,Kka2,kka2_1:4,P00552,1.16705,NO,87,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.917,-3.035,1.118,,1.039,S,L,0.46,1.57,22.675,22.675,65.53,AHO,-1.822,0.168804,0.00791281,1.16705 beta-lactamase_0_E102F,beta-lactamase_0_102,TEM-1,beta-lactamase_0,P62593,1.16737,NO,102,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.118,-4.365,2.247,,0.722,S,B,1.04,1.82,4.773,,73.08,HAH,-1.581,0.0500837,0.00486633,1.16737 beta-lactamase_0_T131G,beta-lactamase_0_131,TEM-1,beta-lactamase_0,P62593,1.16742,NO,131,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.328,-3.298,1.97,,,H,A,0.22,-0.69,3.306,,67.48,PPH,-1.00867,0.0500837,0.00345886,1.16742 kka2_1:4_G181H,kka2_1:4_181,Kka2,kka2_1:4,P00552,1.16745,NO,181,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-2.698,-2.933,0.235,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.168804,0.00728319,1.16745 beta-lactamase_0_S221T,beta-lactamase_0_221,TEM-1,beta-lactamase_0,P62593,1.16746,NO,221,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.754,-3.292,1.538,,0.624,H,A,0.27,-0.2,2.914,,74.48,BPH,-1.59967,0.0500837,0.0046094,1.16746 kka2_1:4_I246K,kka2_1:4_246,Kka2,kka2_1:4,P00552,1.16756,NO,246,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-2.008,-3.871,1.863,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.168804,0.0139479,1.16756 kka2_1:4_E235C,kka2_1:4_235,Kka2,kka2_1:4,P00552,1.16765,NO,235,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.955,-5.156,3.201,,0.631,H,A,1.04,0.12,23.175,23.175,65.53,OAH,-2.07267,0.168804,0.0102806,1.16765 kka2_1:4_D33S,kka2_1:4_33,Kka2,kka2_1:4,P00552,1.1677,NO,33,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.186,-2.451,0.265,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.168804,0.00633568,1.1677 PSD95pdz3_P311F,PSD95pdz3_311,PSD95pdz3,PSD95pdz3,P31016,1.16775,NO,311,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.236,-4.199,2.963,5.76649,,,,,14.78,,,,OOB,-1.409,0.0758425,0.0030796,1.16775 kka2_1:4_S251R,kka2_1:4_251,Kka2,kka2_1:4,P00552,1.16776,NO,251,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.636,-2.795,0.159,,0.712,H,A,0.77,-0.25,,,71.59,APP,-2.09367,0.168804,0.0138916,1.16776 beta-lactamase_0_A148H,beta-lactamase_0_148,TEM-1,beta-lactamase_0,P62593,1.16777,NO,148,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.757,-3.344,1.587,,0.379,H,A,0.46,-0.55,19.42,19.42,72.73,PHH,-1.40167,0.0500837,0.00547053,1.16777 kka2_1:8_M178Q,kka2_1:8_178,Kka2,kka2_1:8,P00552,1.16793,NO,178,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-3.206,-2.478,-0.728,,0.554,,b,1.59,0.68,13.268,13.268,71.59,BHO,-2.154,0.100394,0.00717253,1.16793 kka2_1:8_M178Q,kka2_1:8_178,Kka2,kka2_1:8,P00552,1.16793,NO,178,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-3.206,-2.478,-0.728,,0.554,,b,1.59,0.68,13.268,13.268,71.59,BHO,-2.154,0.100394,0.00717253,1.16793 kka2_1:4_G55Q,kka2_1:4_55,Kka2,kka2_1:4,P00552,1.16797,NO,55,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.625,-4.083,2.458,,0.517,S,b,0.75,1.19,15.753,15.753,63.64,POH,-2.05967,0.168804,0.00667877,1.16797 kka2_1:8_A247G,kka2_1:8_247,Kka2,kka2_1:8,P00552,1.16797,NO,247,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.459,-2.518,0.059,,1.01,S,A,0.46,0.65,18.904,18.904,92.05,HHH,-2.197,0.100394,0.0102428,1.16797 kka2_1:8_A247G,kka2_1:8_247,Kka2,kka2_1:8,P00552,1.16797,NO,247,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.459,-2.518,0.059,,1.01,S,A,0.46,0.65,18.904,18.904,92.05,HHH,-2.197,0.100394,0.0102428,1.16797 kka2_1:8_G21H,kka2_1:8_21,Kka2,kka2_1:8,P00552,1.168,NO,21,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.368,-2.564,1.196,,0.586,T,l,0.29,-0.75,4.889,,71.59,HOH,-2.10167,0.100394,0.00709648,1.168 kka2_1:8_G21H,kka2_1:8_21,Kka2,kka2_1:8,P00552,1.168,NO,21,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.368,-2.564,1.196,,0.586,T,l,0.29,-0.75,4.889,,71.59,HOH,-2.10167,0.100394,0.00709648,1.168 beta-lactamase_0_A247M,beta-lactamase_0_247,TEM-1,beta-lactamase_0,P62593,1.16801,NO,247,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.48,,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.0500837,0.00611275,1.16801 kka2_1:8_E230S,kka2_1:8_230,Kka2,kka2_1:8,P00552,1.16805,NO,230,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.672,-2.395,-0.277,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.100394,0.00920051,1.16805 kka2_1:8_E230S,kka2_1:8_230,Kka2,kka2_1:8,P00552,1.16805,NO,230,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.672,-2.395,-0.277,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.100394,0.00920051,1.16805 kka2_1:4_A110N,kka2_1:4_110,Kka2,kka2_1:4,P00552,1.16807,NO,110,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.064,-3.944,1.88,,0.175,H,A,0.46,-1.19,23.237,23.237,71.59,OHA,-1.91867,0.168804,0.00759851,1.16807 beta-lactamase_0_E164F,beta-lactamase_0_164,TEM-1,beta-lactamase_0,P62593,1.16814,NO,164,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-0.948,-4.341,3.393,,0.011,T,B,1.04,-0.4,1.011,,64.69,HAO,-1.388,0.0500837,0.00137286,1.16814 beta-lactamase_0_A84Q,beta-lactamase_0_84,TEM-1,beta-lactamase_0,P62593,1.16817,NO,84,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.651,-2.658,1.007,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.0500837,0.00503822,1.16817 kka2_1:4_I29N,kka2_1:4_29,Kka2,kka2_1:4,P00552,1.16834,NO,29,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.692,-3.146,1.454,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.168804,0.00619521,1.16834 beta-lactamase_0_D271L,beta-lactamase_0_271,TEM-1,beta-lactamase_0,P62593,1.16836,NO,271,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.0500837,0.00752082,1.16836 kka2_1:8_A14I,kka2_1:8_14,Kka2,kka2_1:8,P00552,1.16841,NO,14,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.837,-3.179,1.342,,0.728,G,A,0.46,0.7,,,71.59,HHH,-1.82567,0.100394,0.00706614,1.16841 kka2_1:8_A14I,kka2_1:8_14,Kka2,kka2_1:8,P00552,1.16841,NO,14,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.837,-3.179,1.342,,0.728,G,A,0.46,0.7,,,71.59,HHH,-1.82567,0.100394,0.00706614,1.16841 kka2_1:8_L174A,kka2_1:8_174,Kka2,kka2_1:8,P00552,1.16845,NO,174,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.952,-2.507,1.555,,,H,A,1.59,-0.31,1.204,,51.89,BHB,-2.08533,0.100394,0.00438501,1.16845 kka2_1:8_L174A,kka2_1:8_174,Kka2,kka2_1:8,P00552,1.16845,NO,174,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.952,-2.507,1.555,,,H,A,1.59,-0.31,1.204,,51.89,BHB,-2.08533,0.100394,0.00438501,1.16845 kka2_1:8_V16A,kka2_1:8_16,Kka2,kka2_1:8,P00552,1.1685,NO,16,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-3.087,-2.407,-0.68,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.100394,0.00694011,1.1685 kka2_1:8_V16A,kka2_1:8_16,Kka2,kka2_1:8,P00552,1.1685,NO,16,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-3.087,-2.407,-0.68,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.100394,0.00694011,1.1685 kka2_1:8_A110Q,kka2_1:8_110,Kka2,kka2_1:8,P00552,1.16851,NO,110,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.064,-2.476,0.412,,0.175,H,A,1.04,-1.19,11.413,11.413,71.59,OHA,-1.91867,0.100394,0.00759851,1.16851 kka2_1:8_A110Q,kka2_1:8_110,Kka2,kka2_1:8,P00552,1.16851,NO,110,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.064,-2.476,0.412,,0.175,H,A,1.04,-1.19,11.413,11.413,71.59,OHA,-1.91867,0.100394,0.00759851,1.16851 kka2_1:8_V242D,kka2_1:8_242,Kka2,kka2_1:8,P00552,1.16854,NO,242,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-2.687,-2.207,-0.48,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.100394,0.0102575,1.16854 kka2_1:8_V242D,kka2_1:8_242,Kka2,kka2_1:8,P00552,1.16854,NO,242,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-2.687,-2.207,-0.48,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.100394,0.0102575,1.16854 beta-lactamase_0_E87H,beta-lactamase_0_87,TEM-1,beta-lactamase_0,P62593,1.16869,NO,87,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.421,-4.575,3.154,,0.048,,B,1.04,0.92,1.159,,64.69,PAP,-1.969,0.0500837,0.00337888,1.16869 kka2_1:8_G95S,kka2_1:8_95,Kka2,kka2_1:8,P00552,1.16869,NO,95,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-2.403,-1.66,-0.743,,0.126,E,B,0.75,-0.74,7.774,,71.59,HOA,-2.198,0.100394,0.00743616,1.16869 kka2_1:8_G95S,kka2_1:8_95,Kka2,kka2_1:8,P00552,1.16869,NO,95,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-2.403,-1.66,-0.743,,0.126,E,B,0.75,-0.74,7.774,,71.59,HOA,-2.198,0.100394,0.00743616,1.16869 kka2_1:8_S204V,kka2_1:8_204,Kka2,kka2_1:8,P00552,1.16892,NO,204,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.353,-3.451,2.098,,0.144,E,A,0.27,-1.2,0.368,,65.53,HPO,-0.953333,0.100394,0.00881794,1.16892 kka2_1:8_S204V,kka2_1:8_204,Kka2,kka2_1:8,P00552,1.16892,NO,204,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.353,-3.451,2.098,,0.144,E,A,0.27,-1.2,0.368,,65.53,HPO,-0.953333,0.100394,0.00881794,1.16892 beta-lactamase_0_T179P,beta-lactamase_0_179,TEM-1,beta-lactamase_0,P62593,1.16893,NO,179,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.085,-3.739,2.654,,,E,B,0.22,-1.38,0.367,,73.08,PPH,-1.557,0.0500837,0.00226045,1.16893 kka2_1:2_L165C,kka2_1:2_165,Kka2,kka2_1:2,P00552,1.16894,NO,165,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-2.453,-5.171,2.718,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.295029,0.00801161,1.16894 kka2_1:4_A14Y,kka2_1:4_14,Kka2,kka2_1:4,P00552,1.16898,NO,14,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.837,-4.418,2.581,,0.728,G,A,0.46,0.7,0.36,,71.59,HHH,-1.82567,0.168804,0.00706614,1.16898 kka2_1:8_S11P,kka2_1:8_11,Kka2,kka2_1:8,P00552,1.16902,NO,11,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.322,-2.34,0.018,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.100394,0.00381691,1.16902 kka2_1:8_S11P,kka2_1:8_11,Kka2,kka2_1:8,P00552,1.16902,NO,11,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.322,-2.34,0.018,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.100394,0.00381691,1.16902 kka2_1:8_A108H,kka2_1:8_108,Kka2,kka2_1:8,P00552,1.16909,NO,108,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.061,-3.555,1.494,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.100394,0.00751209,1.16909 kka2_1:8_A108H,kka2_1:8_108,Kka2,kka2_1:8,P00552,1.16909,NO,108,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.061,-3.555,1.494,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.100394,0.00751209,1.16909 kka2_1:2_L7W,kka2_1:2_7,Kka2,kka2_1:2,P00552,1.16911,NO,7,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.926,-5.046,3.12,,,,,,,3.012,,71.59,OHB,-2.12333,0.295029,0.00269456,1.16911 kka2_1:8_R202A,kka2_1:8_202,Kka2,kka2_1:8,P00552,1.16911,NO,202,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.761,-2.662,0.901,,0.607,E,B,1.2,0.48,1.409,,52.27,OBH,-1.41067,0.100394,0.00696498,1.16911 kka2_1:8_R202A,kka2_1:8_202,Kka2,kka2_1:8,P00552,1.16911,NO,202,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.761,-2.662,0.901,,0.607,E,B,1.2,0.48,1.409,,52.27,OBH,-1.41067,0.100394,0.00696498,1.16911 kka2_1:8_P12G,kka2_1:8_12,Kka2,kka2_1:8,P00552,1.16915,NO,12,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.853,-3.308,2.455,,,.,B,0.52,1.25,2.41,,48.11,POH,-1.80767,0.100394,0.00500011,1.16915 kka2_1:8_P12G,kka2_1:8_12,Kka2,kka2_1:8,P00552,1.16915,NO,12,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-0.853,-3.308,2.455,,,.,B,0.52,1.25,2.41,,48.11,POH,-1.80767,0.100394,0.00500011,1.16915 kka2_1:8_G164E,kka2_1:8_164,Kka2,kka2_1:8,P00552,1.16918,NO,164,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.869,-3.557,2.688,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.100394,0.00442091,1.16918 kka2_1:8_G164E,kka2_1:8_164,Kka2,kka2_1:8,P00552,1.16918,NO,164,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.869,-3.557,2.688,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.100394,0.00442091,1.16918 beta-lactamase_0_R275T,beta-lactamase_0_275,TEM-1,beta-lactamase_0,P62593,1.16932,NO,275,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.0500837,0.0141984,1.16932 kka2_1:2_A14L,kka2_1:2_14,Kka2,kka2_1:2,P00552,1.16932,NO,14,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.837,-3.498,1.661,,0.728,G,A,0.46,0.7,0.36,,71.59,HHH,-1.82567,0.295029,0.00706614,1.16932 beta-lactamase_0_L28I,beta-lactamase_0_28,TEM-1,beta-lactamase_0,P62593,1.16933,NO,28,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.579,-2.204,0.625,,0.277,H,A,0.55,-0.16,9.35,9.35,93.01,PHH,-2.11333,0.0500837,0.00359321,1.16933 kka2_1:4_A172F,kka2_1:4_172,Kka2,kka2_1:4,P00552,1.16939,NO,172,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.757,-4.4,2.643,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.168804,0.0079265,1.16939 beta-lactamase_0_K144F,beta-lactamase_0_144,TEM-1,beta-lactamase_0,P62593,1.16951,NO,144,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-2.388,-4.427,2.039,,0.863,H,A,2.34,1.27,5.696,,77.62,OBA,-1.904,0.0500837,0.00481141,1.16951 kka2_1:8_F37W,kka2_1:8_37,Kka2,kka2_1:8,P00552,1.16952,NO,37,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.427,-2.717,1.29,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.100394,0.00586193,1.16952 kka2_1:8_F37W,kka2_1:8_37,Kka2,kka2_1:8,P00552,1.16952,NO,37,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.427,-2.717,1.29,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.100394,0.00586193,1.16952 kka2_1:8_V75N,kka2_1:8_75,Kka2,kka2_1:8,P00552,1.1697,NO,75,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-2.06,-4.176,2.116,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.100394,0.00693733,1.1697 kka2_1:8_V75N,kka2_1:8_75,Kka2,kka2_1:8,P00552,1.1697,NO,75,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-2.06,-4.176,2.116,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.100394,0.00693733,1.1697 kka2_1:8_Y218W,kka2_1:8_218,Kka2,kka2_1:8,P00552,1.16971,NO,218,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-1.438,-3.229,1.791,,0.122,H,A,1.25,-0.69,2.923,,56.06,BHP,-1.17533,0.100394,0.0126098,1.16971 kka2_1:8_Y218W,kka2_1:8_218,Kka2,kka2_1:8,P00552,1.16971,NO,218,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-1.438,-3.229,1.791,,0.122,H,A,1.25,-0.69,2.923,,56.06,BHP,-1.17533,0.100394,0.0126098,1.16971 kka2_1:8_R122W,kka2_1:8_122,Kka2,kka2_1:8,P00552,1.16972,NO,122,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.175,-5.581,3.406,,0.487,H,A,1.2,0.26,22.675,22.675,71.59,BBH,-1.53833,0.100394,0.00736512,1.16972 kka2_1:8_R122W,kka2_1:8_122,Kka2,kka2_1:8,P00552,1.16972,NO,122,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.175,-5.581,3.406,,0.487,H,A,1.2,0.26,22.675,22.675,71.59,BBH,-1.53833,0.100394,0.00736512,1.16972 kka2_1:4_F171M,kka2_1:4_171,Kka2,kka2_1:4,P00552,1.16978,NO,171,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.326,-4.328,3.002,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.168804,0.00821426,1.16978 beta-lactamase_0_T131A,beta-lactamase_0_131,TEM-1,beta-lactamase_0,P62593,1.16985,NO,131,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.328,-2.085,0.757,,,H,A,0.22,-0.69,3.306,,67.48,PPH,-1.00867,0.0500837,0.00345886,1.16985 kka2_1:2_V16L,kka2_1:2_16,Kka2,kka2_1:2,P00552,1.16985,NO,16,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-3.087,-2.643,-0.444,,0.742,T,A,0.44,0.34,1.746,,71.59,HHA,-2.211,0.295029,0.00694011,1.16985 kka2_1:4_P167A,kka2_1:4_167,Kka2,kka2_1:4,P00552,1.16986,NO,167,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-2.403,-1.382,-1.021,,0.18,H,A,0.52,0.75,3.6,,64.39,HOH,-2.26633,0.168804,0.00543203,1.16986 beta-lactamase_0_E87W,beta-lactamase_0_87,TEM-1,beta-lactamase_0,P62593,1.1699,NO,87,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.421,-5.437,4.016,,0.048,,B,1.04,0.92,1.159,,64.69,PAP,-1.969,0.0500837,0.00337888,1.1699 kka2_1:2_D52V,kka2_1:2_52,Kka2,kka2_1:2,P00552,1.1699,NO,52,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.271,-3.601,1.33,,0.22,E,B,0.75,0.8,1.123,,71.59,PAH,-2.38367,0.295029,0.00175694,1.1699 kka2_1:2_A150K,kka2_1:2_150,Kka2,kka2_1:2,P00552,1.16996,NO,150,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.949,-3.494,2.545,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.295029,0.0045009,1.16996 kka2_1:4_F206W,kka2_1:4_206,Kka2,kka2_1:4,P00552,1.16999,NO,206,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.349,-4.609,3.26,,0.006,E,B,0.58,-1.21,1.342,,63.64,OHH,-1.04,0.168804,0.00936868,1.16999 kka2_1:4_V84K,kka2_1:4_84,Kka2,kka2_1:4,P00552,1.17007,NO,84,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-2.279,-3.653,1.374,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.168804,0.00724019,1.17007 kka2_1:8_I2G,kka2_1:8_2,Kka2,kka2_1:8,P00552,1.17007,NO,2,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.787,-3.438,1.651,,,,,,,,,71.59,HHA,-1.92433,0.100394,0.00246644,1.17007 kka2_1:8_I2G,kka2_1:8_2,Kka2,kka2_1:8,P00552,1.17007,NO,2,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.787,-3.438,1.651,,,,,,,,,71.59,HHA,-1.92433,0.100394,0.00246644,1.17007 kka2_1:8_D23C,kka2_1:8_23,Kka2,kka2_1:8,P00552,1.1701,NO,23,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.459,-3.701,1.242,,0.695,E,B,0.75,-0.65,,,65.53,HAH,-1.94033,0.100394,0.007195,1.1701 kka2_1:8_D23C,kka2_1:8_23,Kka2,kka2_1:8,P00552,1.1701,NO,23,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.459,-3.701,1.242,,0.695,E,B,0.75,-0.65,,,65.53,HAH,-1.94033,0.100394,0.007195,1.1701 beta-lactamase_0_A132S,beta-lactamase_0_132,TEM-1,beta-lactamase_0,P62593,1.17016,NO,132,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-0.9,-2.411,1.511,,,H,A,0.46,-0.93,2.249,,64.69,PHH,-1.138,0.0500837,0.000962524,1.17016 kka2_1:8_D154F,kka2_1:8_154,Kka2,kka2_1:8,P00552,1.17021,NO,154,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.876,-4.375,3.499,,0.457,,b,0.29,1.48,0.844,,52.65,HAP,-1.52467,0.100394,0.00292633,1.17021 kka2_1:8_D154F,kka2_1:8_154,Kka2,kka2_1:8,P00552,1.17021,NO,154,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.876,-4.375,3.499,,0.457,,b,0.29,1.48,0.844,,52.65,HAP,-1.52467,0.100394,0.00292633,1.17021 kka2_1:8_A176M,kka2_1:8_176,Kka2,kka2_1:8,P00552,1.17026,NO,176,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.621,-4.76,3.139,,0.806,H,A,0.46,-0.03,18.904,18.904,65.53,BHB,-2.26667,0.100394,0.0083587,1.17026 kka2_1:8_A176M,kka2_1:8_176,Kka2,kka2_1:8,P00552,1.17026,NO,176,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.621,-4.76,3.139,,0.806,H,A,0.46,-0.03,18.904,18.904,65.53,BHB,-2.26667,0.100394,0.0083587,1.17026 beta-lactamase_0_S201E,beta-lactamase_0_201,TEM-1,beta-lactamase_0,P62593,1.17028,NO,201,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.183,-3.352,2.169,,0.064,H,A,0.27,-0.07,3.54,,64.69,HPB,-1.451,0.0500837,0.00198815,1.17028 kka2_1:4_D33N,kka2_1:4_33,Kka2,kka2_1:4,P00552,1.17042,NO,33,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.186,-2.693,0.507,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.168804,0.00633568,1.17042 beta-lactamase_0_R162Q,beta-lactamase_0_162,TEM-1,beta-lactamase_0,P62593,1.17051,NO,162,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.016,-3.59,2.574,,0.124,S,B,1.2,-0.37,1.026,,64.69,ABH,-1.25,0.0500837,0.000561334,1.17051 kka2_1:8_D157G,kka2_1:8_157,Kka2,kka2_1:8,P00552,1.17056,NO,157,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.993,-2.513,1.52,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.100394,0.0042313,1.17056 kka2_1:8_D157G,kka2_1:8_157,Kka2,kka2_1:8,P00552,1.17056,NO,157,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.993,-2.513,1.52,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.100394,0.0042313,1.17056 kka2_1:8_A129M,kka2_1:8_129,Kka2,kka2_1:8,P00552,1.17064,NO,129,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.656,-4.824,3.168,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.100394,0.00726862,1.17064 kka2_1:8_A129M,kka2_1:8_129,Kka2,kka2_1:8,P00552,1.17064,NO,129,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.656,-4.824,3.168,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.100394,0.00726862,1.17064 beta-lactamase_0_Q267W,beta-lactamase_0_267,TEM-1,beta-lactamase_0,P62593,1.17065,NO,267,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.0500837,0.0102128,1.17065 kka2_1:8_S40W,kka2_1:8_40,Kka2,kka2_1:8,P00552,1.17073,NO,40,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.645,-5.57,2.925,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.100394,0.00693477,1.17073 kka2_1:8_S40W,kka2_1:8_40,Kka2,kka2_1:8,P00552,1.17073,NO,40,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.645,-5.57,2.925,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.100394,0.00693477,1.17073 kka2_1:8_D33T,kka2_1:8_33,Kka2,kka2_1:8,P00552,1.17074,NO,33,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.186,-2.647,0.461,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.100394,0.00633568,1.17074 kka2_1:8_D33T,kka2_1:8_33,Kka2,kka2_1:8,P00552,1.17074,NO,33,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.186,-2.647,0.461,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.100394,0.00633568,1.17074 kka2_1:2_R44A,kka2_1:2_44,Kka2,kka2_1:2,P00552,1.17081,NO,44,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.062,-2.384,0.322,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.295029,0.00745043,1.17081 kka2_1:2_A108D,kka2_1:2_108,Kka2,kka2_1:2,P00552,1.17089,NO,108,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.061,-2.378,0.317,,0.243,.,B,0.46,-1.34,2.462,,71.59,HHO,-1.57033,0.295029,0.00751209,1.17089 beta-lactamase_0_H110L,beta-lactamase_0_110,TEM-1,beta-lactamase_0,P62593,1.17103,NO,110,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-1.706,-3.515,1.809,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.0500837,0.00441499,1.17103 kka2_1:4_D23T,kka2_1:4_23,Kka2,kka2_1:4,P00552,1.17114,NO,23,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.459,-3.106,0.647,,0.695,E,B,0.75,-0.65,2.416,,65.53,HAH,-1.94033,0.168804,0.007195,1.17114 kka2_1:8_A248E,kka2_1:8_248,Kka2,kka2_1:8,P00552,1.17115,NO,248,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.124,-2.197,0.073,,0.825,S,b,1.04,0.46,11.329,11.329,92.05,HHO,-2.15,0.100394,0.0125484,1.17115 kka2_1:8_A248E,kka2_1:8_248,Kka2,kka2_1:8,P00552,1.17115,NO,248,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.124,-2.197,0.073,,0.825,S,b,1.04,0.46,11.329,11.329,92.05,HHO,-2.15,0.100394,0.0125484,1.17115 kka2_1:2_G43Y,kka2_1:2_43,Kka2,kka2_1:2,P00552,1.17123,NO,43,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.587,-3.332,1.745,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.295029,0.0071925,1.17123 beta-lactamase_0_S57Q,beta-lactamase_0_57,TEM-1,beta-lactamase_0,P62593,1.17139,NO,57,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.918,-3.995,2.077,,0.352,E,B,0.27,-0.18,1.454,,72.73,APH,-2.29167,0.0500837,0.00492804,1.17139 beta-lactamase_0_K190P,beta-lactamase_0_190,TEM-1,beta-lactamase_0,P62593,1.17147,NO,190,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.994,-3.086,1.092,,0.371,H,A,2.34,0.16,16.606,16.606,77.62,BBH,-1.64167,0.0500837,0.00574527,1.17147 kka2_1:8_Q252C,kka2_1:8_252,Kka2,kka2_1:8,P00552,1.17148,NO,252,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.63,-5.184,2.554,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.100394,0.0121001,1.17148 kka2_1:8_Q252C,kka2_1:8_252,Kka2,kka2_1:8,P00552,1.17148,NO,252,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.63,-5.184,2.554,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.100394,0.0121001,1.17148 kka2_1:8_Q252F,kka2_1:8_252,Kka2,kka2_1:8,P00552,1.17148,NO,252,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.63,-4.468,1.838,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.100394,0.0121001,1.17148 kka2_1:8_Q252F,kka2_1:8_252,Kka2,kka2_1:8,P00552,1.17148,NO,252,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.63,-4.468,1.838,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.100394,0.0121001,1.17148 kka2_1:8_A71R,kka2_1:8_71,Kka2,kka2_1:8,P00552,1.17153,NO,71,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.824,-2.453,0.629,,0.553,H,A,0.46,0.08,18.64,18.64,64.39,HHP,-1.74033,0.100394,0.00727707,1.17153 kka2_1:8_A71R,kka2_1:8_71,Kka2,kka2_1:8,P00552,1.17153,NO,71,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.824,-2.453,0.629,,0.553,H,A,0.46,0.08,18.64,18.64,64.39,HHP,-1.74033,0.100394,0.00727707,1.17153 kka2_1:4_E161Q,kka2_1:4_161,Kka2,kka2_1:4,P00552,1.17155,NO,161,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.581,-3.792,2.211,,0.829,G,A,1.52,2.24,1.612,,92.05,AAB,-1.861,0.168804,0.00760103,1.17155 kka2_1:8_V16M,kka2_1:8_16,Kka2,kka2_1:8,P00552,1.17156,NO,16,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-3.087,-3.551,0.464,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.100394,0.00694011,1.17156 kka2_1:8_V16M,kka2_1:8_16,Kka2,kka2_1:8,P00552,1.17156,NO,16,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-3.087,-3.551,0.464,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.100394,0.00694011,1.17156 kka2_1:4_A14M,kka2_1:4_14,Kka2,kka2_1:4,P00552,1.17173,NO,14,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.837,-4.736,2.899,,0.728,G,A,0.46,0.7,0.36,,71.59,HHH,-1.82567,0.168804,0.00706614,1.17173 WW_domain_V171S,WW_domain_171,Yap65,WW_domain,P46937,1.17178,NO,171,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.547,-3.339,1.792,,,,,,,3.459,,70.24,AHO,-1.265,0.153962,0.00184125,1.17178 kka2_1:8_A150T,kka2_1:8_150,Kka2,kka2_1:8,P00552,1.1718,NO,150,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.949,-3.378,2.429,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.100394,0.0045009,1.1718 kka2_1:8_A150T,kka2_1:8_150,Kka2,kka2_1:8,P00552,1.1718,NO,150,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.949,-3.378,2.429,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.100394,0.0045009,1.1718 kka2_1:2_Q4M,kka2_1:2_4,Kka2,kka2_1:2,P00552,1.17185,NO,4,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.361,-4.464,2.103,,,,,,,2.026,,71.59,APA,-1.95533,0.295029,0.00239179,1.17185 kka2_1:4_E199W,kka2_1:4_199,Kka2,kka2_1:4,P00552,1.17188,NO,199,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.234,-3.699,1.465,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.168804,0.00854122,1.17188 kka2_1:8_G6H,kka2_1:8_6,Kka2,kka2_1:8,P00552,1.1719,NO,6,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.685,-4.557,2.872,,,,,,,,,71.59,AOH,-1.639,0.100394,0.00204693,1.1719 kka2_1:8_G6H,kka2_1:8_6,Kka2,kka2_1:8,P00552,1.1719,NO,6,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.685,-4.557,2.872,,,,,,,,,71.59,AOH,-1.639,0.100394,0.00204693,1.1719 kka2_1:8_D127R,kka2_1:8_127,Kka2,kka2_1:8,P00552,1.17195,NO,127,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.364,-3.039,1.675,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.100394,0.00660501,1.17195 kka2_1:8_D127R,kka2_1:8_127,Kka2,kka2_1:8,P00552,1.17195,NO,127,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.364,-3.039,1.675,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.100394,0.00660501,1.17195 kka2_1:2_T51S,kka2_1:2_51,Kka2,kka2_1:2,P00552,1.17207,NO,51,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.199,-2.009,-0.19,,0.05,E,B,0.22,-0.05,13.165,13.165,63.64,BPA,-1.76767,0.295029,0.00628861,1.17207 kka2_1:8_A25V,kka2_1:8_25,Kka2,kka2_1:8,P00552,1.1721,NO,25,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.496,-2.849,0.353,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.100394,0.00595636,1.1721 kka2_1:8_A25V,kka2_1:8_25,Kka2,kka2_1:8,P00552,1.1721,NO,25,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.496,-2.849,0.353,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.100394,0.00595636,1.1721 kka2_1:8_T225Y,kka2_1:8_225,Kka2,kka2_1:8,P00552,1.17211,NO,225,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.393,-4.28,1.887,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.100394,0.0113598,1.17211 kka2_1:8_T225Y,kka2_1:8_225,Kka2,kka2_1:8,P00552,1.17211,NO,225,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.393,-4.28,1.887,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.100394,0.0113598,1.17211 kka2_1:4_R173L,kka2_1:4_173,Kka2,kka2_1:4,P00552,1.17212,NO,173,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.407,-2.806,0.399,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.168804,0.00784999,1.17212 kka2_1:1_V242H,kka2_1:1_242,Kka2,kka2_1:1,P00552,1.17214,NO,242,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-2.687,-3.504,0.817,,0.75,H,A,0.44,-0.37,4.987,,71.59,HHH,-2.16533,0.520039,0.0102575,1.17214 kka2_1:4_E86D,kka2_1:4_86,Kka2,kka2_1:4,P00552,1.17214,NO,86,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.86,-1.985,0.125,,0.369,.,B,1.04,1.92,4.451,,63.26,PAH,-1.98067,0.168804,0.00642858,1.17214 kka2_1:4_V83M,kka2_1:4_83,Kka2,kka2_1:4,P00552,1.17216,NO,83,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-2.567,-3.575,1.008,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.168804,0.00650486,1.17216 kka2_1:2_L165Q,kka2_1:2_165,Kka2,kka2_1:2,P00552,1.17222,NO,165,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-2.453,-2.33,-0.123,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.295029,0.00801161,1.17222 beta-lactamase_0_R275L,beta-lactamase_0_275,TEM-1,beta-lactamase_0,P62593,1.17229,NO,275,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.0500837,0.0141984,1.17229 kka2_1:8_A229N,kka2_1:8_229,Kka2,kka2_1:8,P00552,1.17236,NO,229,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.739,-3.848,2.109,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.100394,0.00942138,1.17236 kka2_1:8_A229N,kka2_1:8_229,Kka2,kka2_1:8,P00552,1.17236,NO,229,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.739,-3.848,2.109,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.100394,0.00942138,1.17236 kka2_1:8_C209V,kka2_1:8_209,Kka2,kka2_1:8,P00552,1.17243,NO,209,C,V,CV,Special,Hydrophobic,5.07,5.60847,0.538465,192,121,117,-4,108.5,140,31.5,-0.906,-3.299,2.393,,,,a,1.5,-0.89,0.391,,19.32,AOO,-0.903,0.100394,0.00260862,1.17243 kka2_1:8_C209V,kka2_1:8_209,Kka2,kka2_1:8,P00552,1.17243,NO,209,C,V,CV,Special,Hydrophobic,5.07,5.60847,0.538465,192,121,117,-4,108.5,140,31.5,-0.906,-3.299,2.393,,,,a,1.5,-0.89,0.391,,19.32,AOO,-0.903,0.100394,0.00260862,1.17243 kka2_1:4_Y218F,kka2_1:4_218,Kka2,kka2_1:4,P00552,1.17251,NO,218,Y,F,YF,Hydrophobic,Hydrophobic,5.66,3.32051,-2.33949,22,181,165,-16,193.6,189.9,-3.7,-1.438,-2.611,1.173,,0.122,H,A,0.21,-0.69,1.022,,56.06,BHP,-1.17533,0.168804,0.0126098,1.17251 kka2_1:2_A79D,kka2_1:2_79,Kka2,kka2_1:2,P00552,1.17267,NO,79,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.368,-2.473,0.105,,0.563,.,B,0.46,-0.43,0.475,,71.59,HHH,-1.752,0.295029,0.00664821,1.17267 kka2_1:2_R177A,kka2_1:2_177,Kka2,kka2_1:2,P00552,1.17279,NO,177,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.282,-2.56,0.278,,0.521,T,A,1.2,0.16,1.842,,63.64,HBH,-2.36967,0.295029,0.00768224,1.17279 kka2_1:8_P249H,kka2_1:8_249,Kka2,kka2_1:8,P00552,1.1728,NO,249,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.867,-4.971,3.104,,0.406,.,B,0.52,-0.01,1.699,,92.05,HOA,-1.66867,0.100394,0.011045,1.1728 kka2_1:8_P249H,kka2_1:8_249,Kka2,kka2_1:8,P00552,1.1728,NO,249,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.867,-4.971,3.104,,0.406,.,B,0.52,-0.01,1.699,,92.05,HOA,-1.66867,0.100394,0.011045,1.1728 beta-lactamase_0_E87F,beta-lactamase_0_87,TEM-1,beta-lactamase_0,P62593,1.17282,NO,87,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.421,-4.277,2.856,,0.048,,B,1.04,0.92,1.159,,64.69,PAP,-1.969,0.0500837,0.00337888,1.17282 beta-lactamase_0_L160H,beta-lactamase_0_160,TEM-1,beta-lactamase_0,P62593,1.17299,NO,160,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.977,-4.948,3.971,,0.022,,B,0.55,-0.6,0.68,,44.41,BHA,-0.936,0.0500837,0.00193775,1.17299 beta-lactamase_0_S201F,beta-lactamase_0_201,TEM-1,beta-lactamase_0,P62593,1.17299,NO,201,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.183,-4.138,2.955,,0.064,H,A,0.27,-0.07,3.54,,64.69,HPB,-1.451,0.0500837,0.00198815,1.17299 kka2_1:4_Q42T,kka2_1:4_42,Kka2,kka2_1:4,P00552,1.17301,NO,42,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.907,-2.915,0.008,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.168804,0.00679212,1.17301 kka2_1:4_H139C,kka2_1:4_139,Kka2,kka2_1:4,P00552,1.17303,NO,139,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-2.809,-5.201,2.392,,0.471,H,A,0.17,0.68,12.761,12.761,63.64,BBB,-2.22,0.168804,0.00734779,1.17303 kka2_1:8_D156F,kka2_1:8_156,Kka2,kka2_1:8,P00552,1.17317,NO,156,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.696,-4.395,2.699,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.100394,0.00926998,1.17317 kka2_1:8_D156F,kka2_1:8_156,Kka2,kka2_1:8,P00552,1.17317,NO,156,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.696,-4.395,2.699,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.100394,0.00926998,1.17317 kka2_1:8_P128V,kka2_1:8_128,Kka2,kka2_1:8,P00552,1.17318,NO,128,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.922,-2.023,0.101,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.100394,0.00774689,1.17318 kka2_1:8_P128V,kka2_1:8_128,Kka2,kka2_1:8,P00552,1.17318,NO,128,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.922,-2.023,0.101,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.100394,0.00774689,1.17318 kka2_1:4_A56C,kka2_1:4_56,Kka2,kka2_1:4,P00552,1.17324,NO,56,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.083,-5.094,3.011,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.168804,0.00717715,1.17324 kka2_1:8_R143H,kka2_1:8_143,Kka2,kka2_1:8,P00552,1.17342,NO,143,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.525,-3.575,1.05,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.100394,0.00662247,1.17342 kka2_1:8_R143H,kka2_1:8_143,Kka2,kka2_1:8,P00552,1.17342,NO,143,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.525,-3.575,1.05,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.100394,0.00662247,1.17342 kka2_1:8_R44M,kka2_1:8_44,Kka2,kka2_1:8,P00552,1.17346,NO,44,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.062,-4.711,2.649,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.100394,0.00745043,1.17346 kka2_1:8_R44M,kka2_1:8_44,Kka2,kka2_1:8,P00552,1.17346,NO,44,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.062,-4.711,2.649,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.100394,0.00745043,1.17346 kka2_1:4_A79T,kka2_1:4_79,Kka2,kka2_1:4,P00552,1.17352,NO,79,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.368,-2.485,0.117,,0.563,.,B,0.46,-0.43,2.291,,71.59,HHH,-1.752,0.168804,0.00664821,1.17352 kka2_1:4_D250L,kka2_1:4_250,Kka2,kka2_1:4,P00552,1.17356,NO,250,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.015,-3.81,2.795,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.168804,0.0177103,1.17356 beta-lactamase_0_I277V,beta-lactamase_0_277,TEM-1,beta-lactamase_0,P62593,1.17361,NO,277,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.0500837,0.0169305,1.17361 kka2_1:4_V46Q,kka2_1:4_46,Kka2,kka2_1:4,P00552,1.17367,NO,46,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-2.62,-4.138,1.518,,0.192,.,B,0.44,-1.12,9.564,,92.05,OHH,-1.88633,0.168804,0.00631301,1.17367 kka2_1:8_P76H,kka2_1:8_76,Kka2,kka2_1:8,P00552,1.17369,NO,76,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.449,-4.835,3.386,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.100394,0.00625685,1.17369 kka2_1:8_P76H,kka2_1:8_76,Kka2,kka2_1:8,P00552,1.17369,NO,76,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.449,-4.835,3.386,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.100394,0.00625685,1.17369 kka2_1:8_Q252M,kka2_1:8_252,Kka2,kka2_1:8,P00552,1.17369,NO,252,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.63,-4.83,2.2,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.100394,0.0121001,1.17369 kka2_1:8_Q252M,kka2_1:8_252,Kka2,kka2_1:8,P00552,1.17369,NO,252,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.63,-4.83,2.2,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.100394,0.0121001,1.17369 beta-lactamase_0_I280Y,beta-lactamase_0_280,TEM-1,beta-lactamase_0,P62593,1.17384,NO,280,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.0500837,0.0530888,1.17384 kka2_1:8_Q61D,kka2_1:8_61,Kka2,kka2_1:8,P00552,1.1739,NO,61,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.982,-3.015,0.033,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.100394,0.00612092,1.1739 kka2_1:8_Q61D,kka2_1:8_61,Kka2,kka2_1:8,P00552,1.1739,NO,61,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.982,-3.015,0.033,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.100394,0.00612092,1.1739 beta-lactamase_0_T179G,beta-lactamase_0_179,TEM-1,beta-lactamase_0,P62593,1.17392,NO,179,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.085,-3.296,2.211,,,E,B,0.22,-1.38,0.367,,73.08,PPH,-1.557,0.0500837,0.00226045,1.17392 kka2_1:4_A176I,kka2_1:4_176,Kka2,kka2_1:4,P00552,1.17392,NO,176,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.621,-4.019,2.398,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.168804,0.0083587,1.17392 beta-lactamase_0_P255Q,beta-lactamase_0_255,TEM-1,beta-lactamase_0,P62593,1.17395,NO,255,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.0500837,0.00499612,1.17395 kka2_1:4_L60M,kka2_1:4_60,Kka2,kka2_1:4,P00552,1.17396,NO,60,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.997,-2.995,1.998,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.168804,0.00262176,1.17396 kka2_1:8_L47R,kka2_1:8_47,Kka2,kka2_1:8,P00552,1.17399,NO,47,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.265,-2.763,1.498,,0.139,E,B,1.59,-0.86,5.086,,63.26,HHH,-1.77933,0.100394,0.00509386,1.17399 kka2_1:8_L47R,kka2_1:8_47,Kka2,kka2_1:8,P00552,1.17399,NO,47,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.265,-2.763,1.498,,0.139,E,B,1.59,-0.86,5.086,,63.26,HHH,-1.77933,0.100394,0.00509386,1.17399 kka2_1:8_N200Q,kka2_1:8_200,Kka2,kka2_1:8,P00552,1.174,NO,200,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-2.446,-2.857,0.411,,0.756,T,L,0.43,-0.08,2.528,,64.39,APO,-2.08,0.100394,0.00838549,1.174 kka2_1:8_N200Q,kka2_1:8_200,Kka2,kka2_1:8,P00552,1.174,NO,200,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-2.446,-2.857,0.411,,0.756,T,L,0.43,-0.08,2.528,,64.39,APO,-2.08,0.100394,0.00838549,1.174 kka2_1:8_K175D,kka2_1:8_175,Kka2,kka2_1:8,P00552,1.17402,NO,175,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-2.897,-3.874,0.977,,0.579,H,A,2.34,0.51,15.316,15.316,71.59,HBH,-1.82333,0.100394,0.00693093,1.17402 kka2_1:8_K175D,kka2_1:8_175,Kka2,kka2_1:8,P00552,1.17402,NO,175,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-2.897,-3.874,0.977,,0.579,H,A,2.34,0.51,15.316,15.316,71.59,HBH,-1.82333,0.100394,0.00693093,1.17402 kka2_1:4_A64V,kka2_1:4_64,Kka2,kka2_1:4,P00552,1.17404,NO,64,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.496,-1.905,0.409,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.168804,0.00705578,1.17404 kka2_1:8_R173V,kka2_1:8_173,Kka2,kka2_1:8,P00552,1.17406,NO,173,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.407,-3.707,1.3,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.100394,0.00784999,1.17406 kka2_1:8_R173V,kka2_1:8_173,Kka2,kka2_1:8,P00552,1.17406,NO,173,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.407,-3.707,1.3,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.100394,0.00784999,1.17406 kka2_1:4_A150T,kka2_1:4_150,Kka2,kka2_1:4,P00552,1.17413,NO,150,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-0.949,-3.378,2.429,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.168804,0.0045009,1.17413 kka2_1:2_Q136G,kka2_1:2_136,Kka2,kka2_1:2,P00552,1.17417,NO,136,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-3.021,-2.521,-0.5,,0.331,,b,0.4,0.96,2.726,,92.05,BPH,-2.16933,0.295029,0.00624149,1.17417 beta-lactamase_0_M270D,beta-lactamase_0_270,TEM-1,beta-lactamase_0,P62593,1.17429,NO,270,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.0500837,0.00767762,1.17429 beta-lactamase_0_I261N,beta-lactamase_0_261,TEM-1,beta-lactamase_0,P62593,1.17431,NO,261,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-2.88,,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.0500837,0.0123091,1.17431 kka2_1:8_A172K,kka2_1:8_172,Kka2,kka2_1:8,P00552,1.17435,NO,172,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.757,-3.042,1.285,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.100394,0.0079265,1.17435 kka2_1:8_A172K,kka2_1:8_172,Kka2,kka2_1:8,P00552,1.17435,NO,172,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.757,-3.042,1.285,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.100394,0.0079265,1.17435 kka2_1:4_H162N,kka2_1:4_162,Kka2,kka2_1:4,P00552,1.17437,NO,162,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-2.319,-2.321,0.002,,0.071,G,A,0.17,1.01,3.187,,64.39,ABP,-2.02067,0.168804,0.00616145,1.17437 kka2_1:2_L53Y,kka2_1:2_53,Kka2,kka2_1:2,P00552,1.17455,NO,53,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-2.681,-4.449,1.768,,0.569,E,B,0.55,0.8,19.536,19.536,71.59,AHP,-2.47433,0.295029,0.00671168,1.17455 kka2_1:2_R18E,kka2_1:2_18,Kka2,kka2_1:2,P00552,1.17457,NO,18,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.055,-2.876,0.821,,0.474,T,A,1.2,0.54,8.405,8.405,71.59,ABH,-1.821,0.295029,0.00724065,1.17457 kka2_1:2_C209T,kka2_1:2_209,Kka2,kka2_1:2,P00552,1.17461,NO,209,C,T,CT,Special,Polar,5.07,5.6,0.53,149,121,119,-2,108.5,116.1,7.6,-0.906,-3.473,2.567,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.295029,0.00260862,1.17461 kka2_1:8_T73H,kka2_1:8_73,Kka2,kka2_1:8,P00552,1.17463,NO,73,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.51,-3.503,0.993,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.100394,0.00628605,1.17463 kka2_1:8_T73H,kka2_1:8_73,Kka2,kka2_1:8,P00552,1.17463,NO,73,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.51,-3.503,0.993,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.100394,0.00628605,1.17463 beta-lactamase_0_H94N,beta-lactamase_0_94,TEM-1,beta-lactamase_0,P62593,1.1747,NO,94,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-2.5,-3.811,1.311,,0.776,,B,0.17,1.24,1.176,,77.62,HBH,-1.872,0.0500837,0.00389226,1.1747 beta-lactamase_0_K190H,beta-lactamase_0_190,TEM-1,beta-lactamase_0,P62593,1.17472,NO,190,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.994,-3.068,1.074,,0.371,H,A,2.34,0.16,16.606,16.606,77.62,BBH,-1.64167,0.0500837,0.00574527,1.17472 kka2_1:4_A176G,kka2_1:4_176,Kka2,kka2_1:4,P00552,1.17475,NO,176,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.621,-3.323,1.702,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.168804,0.0083587,1.17475 kka2_1:2_R143K,kka2_1:2_143,Kka2,kka2_1:2,P00552,1.17478,NO,143,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.525,-3.061,0.536,,0.325,H,A,0.16,1.22,14.853,14.853,65.53,ABH,-1.86833,0.295029,0.00662247,1.17478 beta-lactamase_0_E56D,beta-lactamase_0_56,TEM-1,beta-lactamase_0,P62593,1.1748,NO,56,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.043,-3.248,1.205,,0.198,E,B,1.04,0.31,1.491,,72.73,HAP,-1.94033,0.0500837,0.00238534,1.1748 kka2_1:2_D23C,kka2_1:2_23,Kka2,kka2_1:2,P00552,1.17486,NO,23,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.459,-3.701,1.242,,0.695,E,B,0.75,-0.65,18.207,18.207,65.53,HAH,-1.94033,0.295029,0.007195,1.17486 WW_domain_D194C,WW_domain_194,Yap65,WW_domain,P46937,1.17491,NO,194,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.536,-4.989,3.453,5.95614,,,,,,1.948,,74.4,HAP,-1.78933,0.153962,0.00483742,1.17491 kka2_1:2_A172D,kka2_1:2_172,Kka2,kka2_1:2,P00552,1.17494,NO,172,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.757,-2.549,0.792,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.295029,0.0079265,1.17494 kka2_1:2_L232F,kka2_1:2_232,Kka2,kka2_1:2,P00552,1.17506,NO,232,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.514,-2.061,0.547,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.295029,0.00800103,1.17506 kka2_1:8_A9L,kka2_1:8_9,Kka2,kka2_1:8,P00552,1.1751,NO,9,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.079,-2.291,0.212,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.100394,0.00273264,1.1751 kka2_1:8_A9L,kka2_1:8_9,Kka2,kka2_1:8,P00552,1.1751,NO,9,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.079,-2.291,0.212,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.100394,0.00273264,1.1751 kka2_1:4_P249M,kka2_1:4_249,Kka2,kka2_1:4,P00552,1.17512,NO,249,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.867,-3.186,1.319,,0.406,.,B,0.52,-0.01,,,92.05,HOA,-1.66867,0.168804,0.011045,1.17512 beta-lactamase_0_T139K,beta-lactamase_0_139,TEM-1,beta-lactamase_0,P62593,1.17516,NO,139,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.901,-3.403,1.502,,0.216,H,A,0.22,0.39,0.421,,77.62,PPH,-2.04667,0.0500837,0.00441837,1.17516 kka2_1:2_E230A,kka2_1:2_230,Kka2,kka2_1:2,P00552,1.17517,NO,230,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.672,-2.43,-0.242,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.295029,0.00920051,1.17517 kka2_1:2_Q100E,kka2_1:2_100,Kka2,kka2_1:2,P00552,1.17518,NO,100,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.77,-2.743,-0.027,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.295029,0.0066405,1.17518 beta-lactamase_0_T147Q,beta-lactamase_0_147,TEM-1,beta-lactamase_0,P62593,1.1753,NO,147,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.149,-3.979,2.83,,0.281,H,A,0.22,-0.68,3.487,,64.34,HPH,-1.456,0.0500837,0.00226017,1.1753 beta-lactamase_0_E272R,beta-lactamase_0_272,TEM-1,beta-lactamase_0,P62593,1.17534,NO,272,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.0500837,0.00545371,1.17534 kka2_1:8_E161C,kka2_1:8_161,Kka2,kka2_1:8,P00552,1.17536,NO,161,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.581,-5.043,3.462,,0.829,G,A,1.04,2.24,11.923,11.923,92.05,AAB,-1.861,0.100394,0.00760103,1.17536 kka2_1:8_E161C,kka2_1:8_161,Kka2,kka2_1:8,P00552,1.17536,NO,161,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.581,-5.043,3.462,,0.829,G,A,1.04,2.24,11.923,11.923,92.05,AAB,-1.861,0.100394,0.00760103,1.17536 kka2_1:4_T28E,kka2_1:4_28,Kka2,kka2_1:4,P00552,1.17537,NO,28,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.883,-2.677,0.794,,0.353,S,B,0.82,2.02,4.415,,63.64,PPH,-1.74467,0.168804,0.00743084,1.17537 kka2_1:8_Q4S,kka2_1:8_4,Kka2,kka2_1:8,P00552,1.17538,NO,4,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.361,-2.105,-0.256,,,,,,,2.026,,71.59,APA,-1.95533,0.100394,0.00239179,1.17538 kka2_1:8_Q4S,kka2_1:8_4,Kka2,kka2_1:8,P00552,1.17538,NO,4,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.361,-2.105,-0.256,,,,,,,2.026,,71.59,APA,-1.95533,0.100394,0.00239179,1.17538 kka2_1:2_A110H,kka2_1:2_110,Kka2,kka2_1:2,P00552,1.17539,NO,110,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.064,-3.65,1.586,,0.175,H,A,0.46,-1.19,23.237,23.237,71.59,OHA,-1.91867,0.295029,0.00759851,1.17539 kka2_1:8_T146Q,kka2_1:8_146,Kka2,kka2_1:8,P00552,1.17544,NO,146,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.978,-2.971,-0.007,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.100394,0.00606474,1.17544 kka2_1:8_T146Q,kka2_1:8_146,Kka2,kka2_1:8,P00552,1.17544,NO,146,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.978,-2.971,-0.007,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.100394,0.00606474,1.17544 kka2_1:2_P167I,kka2_1:2_167,Kka2,kka2_1:2,P00552,1.17547,NO,167,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-2.403,-2.742,0.339,,0.18,H,A,0.52,0.75,3.6,,64.39,HOH,-2.26633,0.295029,0.00543203,1.17547 kka2_1:8_H162N,kka2_1:8_162,Kka2,kka2_1:8,P00552,1.17553,NO,162,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-2.319,-2.321,0.002,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.100394,0.00616145,1.17553 kka2_1:8_H162N,kka2_1:8_162,Kka2,kka2_1:8,P00552,1.17553,NO,162,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-2.319,-2.321,0.002,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.100394,0.00616145,1.17553 kka2_1:4_E169A,kka2_1:4_169,Kka2,kka2_1:4,P00552,1.17554,NO,169,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.996,-2.303,0.307,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.168804,0.00730086,1.17554 kka2_1:2_L53C,kka2_1:2_53,Kka2,kka2_1:2,P00552,1.17559,NO,53,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-2.681,-5.19,2.509,,0.569,E,B,0.55,0.8,19.536,19.536,71.59,AHP,-2.47433,0.295029,0.00671168,1.17559 kka2_1:2_E160F,kka2_1:2_160,Kka2,kka2_1:2,P00552,1.17561,NO,160,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.683,-4.47,2.787,,0.989,G,A,1.04,2.28,3.948,,71.59,AAA,-1.36133,0.295029,0.00935762,1.17561 kka2_1:2_Q42I,kka2_1:2_42,Kka2,kka2_1:2,P00552,1.17569,NO,42,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.907,-4.147,1.24,,1.044,T,B,0.64,-0.8,2.792,,71.59,HPO,-2.12433,0.295029,0.00679212,1.17569 beta-lactamase_0_A77K,beta-lactamase_0_77,TEM-1,beta-lactamase_0,P62593,1.17571,NO,77,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.234,-3.628,2.394,,0.039,H,A,0.46,-0.56,2.591,,64.34,OHH,-1.294,0.0500837,0.00282362,1.17571 kka2_1:2_M178F,kka2_1:2_178,Kka2,kka2_1:2,P00552,1.17582,NO,178,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-3.206,-4.351,1.145,,0.554,.,b,0.55,0.68,3.152,,71.59,BHO,-2.154,0.295029,0.00717253,1.17582 kka2_1:2_R239E,kka2_1:2_239,Kka2,kka2_1:2,P00552,1.1759,NO,239,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.949,-2.985,0.036,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.295029,0.00835326,1.1759 WW_domain_V171D,WW_domain_171,Yap65,WW_domain,P46937,1.17594,NO,171,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.547,-3.838,2.291,,,,,,,3.459,,70.24,AHO,-1.265,0.153962,0.00184125,1.17594 kka2_1:8_A176T,kka2_1:8_176,Kka2,kka2_1:8,P00552,1.17596,NO,176,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.621,-2.528,0.907,,0.806,H,A,0.46,-0.03,18.904,18.904,65.53,BHB,-2.26667,0.100394,0.0083587,1.17596 kka2_1:8_A176T,kka2_1:8_176,Kka2,kka2_1:8,P00552,1.17596,NO,176,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.621,-2.528,0.907,,0.806,H,A,0.46,-0.03,18.904,18.904,65.53,BHB,-2.26667,0.100394,0.0083587,1.17596 kka2_1:4_V16I,kka2_1:4_16,Kka2,kka2_1:4,P00552,1.17598,NO,16,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-3.087,-3.948,0.861,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.168804,0.00694011,1.17598 kka2_1:8_T146C,kka2_1:8_146,Kka2,kka2_1:8,P00552,1.176,NO,146,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.978,-5.009,2.031,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.100394,0.00606474,1.176 kka2_1:8_T146C,kka2_1:8_146,Kka2,kka2_1:8,P00552,1.176,NO,146,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.978,-5.009,2.031,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.100394,0.00606474,1.176 beta-lactamase_0_I206A,beta-lactamase_0_206,TEM-1,beta-lactamase_0,P62593,1.17601,NO,206,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-2.429,-2.387,-0.042,,0.173,H,A,0.48,-0.34,3.411,,77.62,HHA,-1.805,0.0500837,0.00528934,1.17601 kka2_1:2_D23G,kka2_1:2_23,Kka2,kka2_1:2,P00552,1.17601,NO,23,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.459,-2.651,0.192,,0.695,E,B,0.75,-0.65,18.207,18.207,65.53,HAH,-1.94033,0.295029,0.007195,1.17601 beta-lactamase_0_P255H,beta-lactamase_0_255,TEM-1,beta-lactamase_0,P62593,1.17605,NO,255,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.0500837,0.00499612,1.17605 kka2_1:1_G234R,kka2_1:1_234,Kka2,kka2_1:1,P00552,1.17609,NO,234,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-2.9,-3.848,0.948,,0.494,H,A,0.29,-0.29,1.753,,71.59,OOA,-1.86767,0.520039,0.00984449,1.17609 beta-lactamase_0_I245Q,beta-lactamase_0_245,TEM-1,beta-lactamase_0,P62593,1.17614,NO,245,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.0500837,0.00391032,1.17614 kka2_1:4_D154R,kka2_1:4_154,Kka2,kka2_1:4,P00552,1.17615,NO,154,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-0.876,-3.899,3.023,,0.457,,b,0.29,1.48,15.641,15.641,52.65,HAP,-1.52467,0.168804,0.00292633,1.17615 kka2_1:4_A255M,kka2_1:4_255,Kka2,kka2_1:4,P00552,1.17621,NO,255,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.715,-4.815,3.1,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.168804,0.0126809,1.17621 beta-lactamase_0_E166D,beta-lactamase_0_166,TEM-1,beta-lactamase_0,P62593,1.17622,NO,166,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.756,-2.259,0.503,,0.508,G,A,1.04,1.05,17.227,17.227,73.08,OAH,-1.42233,0.0500837,0.00512989,1.17622 kka2_1:8_G10R,kka2_1:8_10,Kka2,kka2_1:8,P00552,1.17623,NO,10,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.921,-2.648,0.727,,,,,,,1.862,,71.59,HOP,-2.10733,0.100394,0.00289233,1.17623 kka2_1:8_G10R,kka2_1:8_10,Kka2,kka2_1:8,P00552,1.17623,NO,10,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.921,-2.648,0.727,,,,,,,1.862,,71.59,HOP,-2.10733,0.100394,0.00289233,1.17623 kka2_1:4_S104Q,kka2_1:4_104,Kka2,kka2_1:4,P00552,1.17627,NO,104,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.436,-3.082,1.646,,0.536,T,A,0.27,-1.11,0.357,,63.64,HPP,-1.91433,0.168804,0.00555207,1.17627 kka2_1:2_D23V,kka2_1:2_23,Kka2,kka2_1:2,P00552,1.17629,NO,23,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.459,-2.803,0.344,,0.695,E,B,0.75,-0.65,18.207,18.207,65.53,HAH,-1.94033,0.295029,0.007195,1.17629 beta-lactamase_0_A211W,beta-lactamase_0_211,TEM-1,beta-lactamase_0,P62593,1.17634,NO,211,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.896,-5.506,3.61,,0.369,T,A,0.46,-0.69,8.527,8.527,77.62,AHA,-1.94633,0.0500837,0.00648183,1.17634 beta-lactamase_0_T131R,beta-lactamase_0_131,TEM-1,beta-lactamase_0,P62593,1.17644,NO,131,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.328,-2.888,1.56,,,H,A,0.22,-0.69,3.306,,67.48,PPH,-1.00867,0.0500837,0.00345886,1.17644 kka2_1:8_I254W,kka2_1:8_254,Kka2,kka2_1:8,P00552,1.17647,NO,254,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.933,-5.273,3.34,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.100394,0.0132375,1.17647 kka2_1:8_I254W,kka2_1:8_254,Kka2,kka2_1:8,P00552,1.17647,NO,254,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.933,-5.273,3.34,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.100394,0.0132375,1.17647 kka2_1:4_Q155G,kka2_1:4_155,Kka2,kka2_1:4,P00552,1.17648,NO,155,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.606,-2.641,0.035,,0.525,T,A,0.64,1.49,1.592,,63.64,APA,-1.726,0.168804,0.00641853,1.17648 kka2_1:8_V153I,kka2_1:8_153,Kka2,kka2_1:8,P00552,1.17649,NO,153,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.092,-1.693,0.601,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.100394,0.00501119,1.17649 kka2_1:8_V153I,kka2_1:8_153,Kka2,kka2_1:8,P00552,1.17649,NO,153,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.092,-1.693,0.601,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.100394,0.00501119,1.17649 kka2_1:2_E231A,kka2_1:2_231,Kka2,kka2_1:2,P00552,1.17652,NO,231,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.002,-3.339,1.337,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.295029,0.00732383,1.17652 kka2_1:8_P98V,kka2_1:8_98,Kka2,kka2_1:8,P00552,1.17659,NO,98,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.526,-3.691,2.165,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.100394,0.00622754,1.17659 kka2_1:8_P98V,kka2_1:8_98,Kka2,kka2_1:8,P00552,1.17659,NO,98,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.526,-3.691,2.165,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.100394,0.00622754,1.17659 kka2_1:8_S11N,kka2_1:8_11,Kka2,kka2_1:8,P00552,1.17663,NO,11,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.322,-3.885,1.563,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.100394,0.00381691,1.17663 kka2_1:8_S11N,kka2_1:8_11,Kka2,kka2_1:8,P00552,1.17663,NO,11,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.322,-3.885,1.563,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.100394,0.00381691,1.17663 beta-lactamase_0_E108D,beta-lactamase_0_108,TEM-1,beta-lactamase_0,P62593,1.1767,NO,108,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.46,-2.67,1.21,,0.572,G,A,1.04,1.87,8.602,8.602,72.73,PAB,-1.437,0.0500837,0.00413372,1.1767 beta-lactamase_0_A200Q,beta-lactamase_0_200,TEM-1,beta-lactamase_0,P62593,1.17672,NO,200,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.878,-3.113,1.235,,0.757,H,A,0.46,-0.19,16.368,16.368,77.62,HHP,-2.001,0.0500837,0.0060056,1.17672 kka2_1:4_A41T,kka2_1:4_41,Kka2,kka2_1:4,P00552,1.17673,NO,41,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.879,-3.68,1.801,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.168804,0.00543332,1.17673 kka2_1:8_V75M,kka2_1:8_75,Kka2,kka2_1:8,P00552,1.17674,NO,75,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-2.06,-2.759,0.699,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.100394,0.00693733,1.17674 kka2_1:8_V75M,kka2_1:8_75,Kka2,kka2_1:8,P00552,1.17674,NO,75,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-2.06,-2.759,0.699,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.100394,0.00693733,1.17674 kka2_1:4_V16M,kka2_1:4_16,Kka2,kka2_1:4,P00552,1.1768,NO,16,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-3.087,-3.551,0.464,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.168804,0.00694011,1.1768 kka2_1:2_S54T,kka2_1:2_54,Kka2,kka2_1:2,P00552,1.17685,NO,54,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.471,-2.979,0.508,,0.408,S,b,0.27,1.01,0.393,,71.59,HPO,-2.259,0.295029,0.00782867,1.17685 kka2_1:8_T125G,kka2_1:8_125,Kka2,kka2_1:8,P00552,1.17689,NO,125,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.622,-2.508,-0.114,,0.791,T,A,0.22,0.33,2.675,,92.05,BPH,-1.56933,0.100394,0.00821755,1.17689 kka2_1:8_T125G,kka2_1:8_125,Kka2,kka2_1:8,P00552,1.17689,NO,125,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.622,-2.508,-0.114,,0.791,T,A,0.22,0.33,2.675,,92.05,BPH,-1.56933,0.100394,0.00821755,1.17689 kka2_1:4_V49A,kka2_1:4_49,Kka2,kka2_1:4,P00552,1.17706,NO,49,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.614,-2.584,0.97,,,E,B,0.44,-0.77,1.233,,64.39,HHB,-1.3,0.168804,0.00615685,1.17706 WW_domain_D170T,WW_domain_170,Yap65,WW_domain,P46937,1.17706,NO,170,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.213,-3.261,2.048,,,,,,,0.399,,15.87,OAH,-1.38,0.153962,0.00123319,1.17706 kka2_1:4_G74S,kka2_1:4_74,Kka2,kka2_1:4,P00552,1.17713,NO,74,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.18,-2.717,1.537,,0.621,T,l,0.75,0.2,1.032,,64.39,POH,-1.91667,0.168804,0.00587035,1.17713 kka2_1:4_S114W,kka2_1:4_114,Kka2,kka2_1:4,P00552,1.17713,NO,114,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.527,-5.559,3.032,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.168804,0.00705262,1.17713 kka2_1:8_A41I,kka2_1:8_41,Kka2,kka2_1:8,P00552,1.17721,NO,41,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.879,-3.958,2.079,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.100394,0.00543332,1.17721 kka2_1:8_A41I,kka2_1:8_41,Kka2,kka2_1:8,P00552,1.17721,NO,41,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.879,-3.958,2.079,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.100394,0.00543332,1.17721 kka2_1:4_I29M,kka2_1:4_29,Kka2,kka2_1:4,P00552,1.17725,NO,29,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.692,-3.049,1.357,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.168804,0.00619521,1.17725 kka2_1:2_L103K,kka2_1:2_103,Kka2,kka2_1:2,P00552,1.1773,NO,103,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-2.362,-3.65,1.288,,0.394,T,A,0.55,-0.99,3.499,,63.64,HHP,-1.534,0.295029,0.00574792,1.1773 PSD95pdz3_G335P,PSD95pdz3_335,PSD95pdz3,PSD95pdz3,P31016,1.17732,NO,335,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.008,-3.561,2.553,4.76223,,,,,22.4225,,,,AOH,-1.34733,0.0758425,0.000900493,1.17732 kka2_1:8_G10S,kka2_1:8_10,Kka2,kka2_1:8,P00552,1.17738,NO,10,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.921,-3.23,1.309,,,,,,,1.862,,71.59,HOP,-2.10733,0.100394,0.00289233,1.17738 kka2_1:8_G10S,kka2_1:8_10,Kka2,kka2_1:8,P00552,1.17738,NO,10,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.921,-3.23,1.309,,,,,,,1.862,,71.59,HOP,-2.10733,0.100394,0.00289233,1.17738 kka2_1:8_W24I,kka2_1:8_24,Kka2,kka2_1:8,P00552,1.17755,NO,24,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-1.779,-2.156,0.377,,0.477,E,B,1.51,-0.21,2.503,,56.06,AHH,-2.24467,0.100394,0.00631564,1.17755 kka2_1:8_W24I,kka2_1:8_24,Kka2,kka2_1:8,P00552,1.17755,NO,24,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-1.779,-2.156,0.377,,0.477,E,B,1.51,-0.21,2.503,,56.06,AHH,-2.24467,0.100394,0.00631564,1.17755 kka2_1:8_E230R,kka2_1:8_230,Kka2,kka2_1:8,P00552,1.17758,NO,230,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.672,-2.504,-0.168,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.100394,0.00920051,1.17758 kka2_1:8_E230R,kka2_1:8_230,Kka2,kka2_1:8,P00552,1.17758,NO,230,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.672,-2.504,-0.168,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.100394,0.00920051,1.17758 kka2_1:8_D23V,kka2_1:8_23,Kka2,kka2_1:8,P00552,1.17759,NO,23,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.459,-2.803,0.344,,0.695,E,B,0.75,-0.65,,,65.53,HAH,-1.94033,0.100394,0.007195,1.17759 kka2_1:8_D23V,kka2_1:8_23,Kka2,kka2_1:8,P00552,1.17759,NO,23,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.459,-2.803,0.344,,0.695,E,B,0.75,-0.65,,,65.53,HAH,-1.94033,0.100394,0.007195,1.17759 kka2_1:4_G74E,kka2_1:4_74,Kka2,kka2_1:4,P00552,1.17773,NO,74,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.18,-2.749,1.569,,0.621,T,l,0.75,0.2,1.032,,64.39,POH,-1.91667,0.168804,0.00587035,1.17773 beta-lactamase_0_R202T,beta-lactamase_0_202,TEM-1,beta-lactamase_0,P62593,1.17776,NO,202,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.292,-3.438,2.146,,0.188,H,A,1.2,0.62,7.016,,77.62,PBP,-1.54767,0.0500837,0.00321899,1.17776 kka2_1:8_F20D,kka2_1:8_20,Kka2,kka2_1:8,P00552,1.17779,NO,20,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-3.354,-3.734,0.38,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.100394,0.00701744,1.17779 kka2_1:8_F20D,kka2_1:8_20,Kka2,kka2_1:8,P00552,1.17779,NO,20,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-3.354,-3.734,0.38,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.100394,0.00701744,1.17779 kka2_1:4_G151L,kka2_1:4_151,Kka2,kka2_1:4,P00552,1.1778,NO,151,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.873,-3.818,2.945,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.168804,0.00339918,1.1778 beta-lactamase_0_K30W,beta-lactamase_0_30,TEM-1,beta-lactamase_0,P62593,1.17781,NO,30,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-2.307,-5.404,3.097,,0.142,H,A,2.34,-0.65,1.491,,93.01,HBH,-2.32833,0.0500837,0.00448593,1.17781 beta-lactamase_0_T179S,beta-lactamase_0_179,TEM-1,beta-lactamase_0,P62593,1.17782,NO,179,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.085,-2.228,1.143,,,E,B,0.22,-1.38,0.367,,73.08,PPH,-1.557,0.0500837,0.00226045,1.17782 beta-lactamase_0_R220M,beta-lactamase_0_220,TEM-1,beta-lactamase_0,P62593,1.17784,NO,220,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-0.942,-4.506,3.564,,0.295,I,A,1.2,-0.76,21.573,21.573,74.48,HBP,-1.33633,0.0500837,0.00232421,1.17784 kka2_1:4_V242S,kka2_1:4_242,Kka2,kka2_1:4,P00552,1.17784,NO,242,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-2.687,-3.455,0.768,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.168804,0.0102575,1.17784 beta-lactamase_0_G236S,beta-lactamase_0_236,TEM-1,beta-lactamase_0,P62593,1.17801,NO,236,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-0.784,-2.475,1.691,,0.241,,b,0.29,-0.59,3.506,,64.69,HOO,-1.025,0.0500837,0.00162372,1.17801 kka2_1:8_M178G,kka2_1:8_178,Kka2,kka2_1:8,P00552,1.17803,NO,178,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-3.206,-2.978,-0.228,,0.554,,b,1.59,0.68,13.268,13.268,71.59,BHO,-2.154,0.100394,0.00717253,1.17803 kka2_1:8_M178G,kka2_1:8_178,Kka2,kka2_1:8,P00552,1.17803,NO,178,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-3.206,-2.978,-0.228,,0.554,,b,1.59,0.68,13.268,13.268,71.59,BHO,-2.154,0.100394,0.00717253,1.17803 beta-lactamase_0_D212Y,beta-lactamase_0_212,TEM-1,beta-lactamase_0,P62593,1.17804,NO,212,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.624,-4.398,2.774,,0.037,,b,0.75,-0.58,3.34,,74.48,HAB,-1.77667,0.0500837,0.00644302,1.17804 kka2_1:4_E161D,kka2_1:4_161,Kka2,kka2_1:4,P00552,1.17804,NO,161,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.581,-2.26,0.679,,0.829,G,A,1.52,2.24,1.612,,92.05,AAB,-1.861,0.168804,0.00760103,1.17804 kka2_1:4_R173D,kka2_1:4_173,Kka2,kka2_1:4,P00552,1.17809,NO,173,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.407,-2.431,0.024,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.168804,0.00784999,1.17809 kka2_1:4_G10W,kka2_1:4_10,Kka2,kka2_1:4,P00552,1.17811,NO,10,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.921,-5.359,3.438,,,,,,,1.862,,71.59,HOP,-2.10733,0.168804,0.00289233,1.17811 kka2_1:2_A35M,kka2_1:2_35,Kka2,kka2_1:2,P00552,1.17812,NO,35,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.127,-3.59,1.463,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.295029,0.00630016,1.17812 kka2_1:2_A166I,kka2_1:2_166,Kka2,kka2_1:2,P00552,1.17822,NO,166,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.407,-3.972,1.565,,0.534,.,B,0.46,1.03,23.175,23.175,71.59,HHO,-2.421,0.295029,0.00799912,1.17822 kka2_1:2_A176R,kka2_1:2_176,Kka2,kka2_1:2,P00552,1.17822,NO,176,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.621,-2.52,0.899,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.295029,0.0083587,1.17822 beta-lactamase_0_G243N,beta-lactamase_0_243,TEM-1,beta-lactamase_0,P62593,1.17823,NO,243,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.0500837,0.00464034,1.17823 kka2_1:8_T72D,kka2_1:8_72,Kka2,kka2_1:8,P00552,1.17825,NO,72,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.38,-3.042,0.662,,0.784,H,A,0.22,0.29,3.603,,65.53,HPP,-2.238,0.100394,0.00750756,1.17825 kka2_1:8_T72D,kka2_1:8_72,Kka2,kka2_1:8,P00552,1.17825,NO,72,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.38,-3.042,0.662,,0.784,H,A,0.22,0.29,3.603,,65.53,HPP,-2.238,0.100394,0.00750756,1.17825 kka2_1:8_E161I,kka2_1:8_161,Kka2,kka2_1:8,P00552,1.17826,NO,161,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.581,-3.91,2.329,,0.829,G,A,1.04,2.24,11.923,11.923,92.05,AAB,-1.861,0.100394,0.00760103,1.17826 kka2_1:8_E161I,kka2_1:8_161,Kka2,kka2_1:8,P00552,1.17826,NO,161,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.581,-3.91,2.329,,0.829,G,A,1.04,2.24,11.923,11.923,92.05,AAB,-1.861,0.100394,0.00760103,1.17826 kka2_1:2_D238Y,kka2_1:2_238,Kka2,kka2_1:2,P00552,1.17828,NO,238,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-2.83,-4.447,1.617,,0.604,H,A,0.75,-0.33,22.789,22.789,92.05,HAB,-2.633,0.295029,0.0113863,1.17828 kka2_1:4_G55N,kka2_1:4_55,Kka2,kka2_1:4,P00552,1.17831,NO,55,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.625,-3.05,1.425,,0.517,S,b,0.75,1.19,15.753,15.753,63.64,POH,-2.05967,0.168804,0.00667877,1.17831 kka2_1:4_A176P,kka2_1:4_176,Kka2,kka2_1:4,P00552,1.17832,NO,176,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.621,-3.934,2.313,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.168804,0.0083587,1.17832 kka2_1:8_S114N,kka2_1:8_114,Kka2,kka2_1:8,P00552,1.17832,NO,114,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.527,-3.164,0.637,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.100394,0.00705262,1.17832 kka2_1:8_S114N,kka2_1:8_114,Kka2,kka2_1:8,P00552,1.17832,NO,114,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.527,-3.164,0.637,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.100394,0.00705262,1.17832 PSD95pdz3_H317M,PSD95pdz3_317,PSD95pdz3,PSD95pdz3,P31016,1.17842,NO,317,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-1.627,-4.387,2.76,6.19713,,,,,25.885,,,,HBB,-1.613,0.0758425,0.00111619,1.17842 kka2_1:8_G21A,kka2_1:8_21,Kka2,kka2_1:8,P00552,1.1785,NO,21,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.368,-2.331,0.963,,0.586,T,l,0.29,-0.75,4.889,,71.59,HOH,-2.10167,0.100394,0.00709648,1.1785 kka2_1:8_G21A,kka2_1:8_21,Kka2,kka2_1:8,P00552,1.1785,NO,21,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.368,-2.331,0.963,,0.586,T,l,0.29,-0.75,4.889,,71.59,HOH,-2.10167,0.100394,0.00709648,1.1785 kka2_1:8_G151M,kka2_1:8_151,Kka2,kka2_1:8,P00552,1.17855,NO,151,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.873,-4.939,4.066,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.100394,0.00339918,1.17855 kka2_1:8_G151M,kka2_1:8_151,Kka2,kka2_1:8,P00552,1.17855,NO,151,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.873,-4.939,4.066,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.100394,0.00339918,1.17855 beta-lactamase_0_Q203F,beta-lactamase_0_203,TEM-1,beta-lactamase_0,P62593,1.17856,NO,203,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.168,-4.379,2.211,,0.47,H,A,0.64,-0.38,14.541,14.541,65.38,BPP,-1.614,0.0500837,0.00631514,1.17856 kka2_1:4_Q27T,kka2_1:4_27,Kka2,kka2_1:4,P00552,1.17859,NO,27,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-1.659,-3.598,1.939,,0.608,,A,0.4,0.71,1.498,,65.53,PPP,-1.90733,0.168804,0.00595365,1.17859 kka2_1:8_A108T,kka2_1:8_108,Kka2,kka2_1:8,P00552,1.17871,NO,108,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.061,-2.374,0.313,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.100394,0.00751209,1.17871 kka2_1:8_A108T,kka2_1:8_108,Kka2,kka2_1:8,P00552,1.17871,NO,108,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.061,-2.374,0.313,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.100394,0.00751209,1.17871 kka2_1:8_P76N,kka2_1:8_76,Kka2,kka2_1:8,P00552,1.17871,NO,76,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.449,-3.923,2.474,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.100394,0.00625685,1.17871 kka2_1:8_P76N,kka2_1:8_76,Kka2,kka2_1:8,P00552,1.17871,NO,76,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.449,-3.923,2.474,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.100394,0.00625685,1.17871 kka2_1:8_T28E,kka2_1:8_28,Kka2,kka2_1:8,P00552,1.17873,NO,28,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.883,-2.677,0.794,,0.353,S,B,0.22,2.02,18.114,18.114,63.64,PPH,-1.74467,0.100394,0.00743084,1.17873 kka2_1:8_T28E,kka2_1:8_28,Kka2,kka2_1:8,P00552,1.17873,NO,28,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.883,-2.677,0.794,,0.353,S,B,0.22,2.02,18.114,18.114,63.64,PPH,-1.74467,0.100394,0.00743084,1.17873 kka2_1:4_G181A,kka2_1:4_181,Kka2,kka2_1:4,P00552,1.17882,NO,181,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-2.698,-2.631,-0.067,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.168804,0.00728319,1.17882 kka2_1:4_G74D,kka2_1:4_74,Kka2,kka2_1:4,P00552,1.17898,NO,74,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.18,-1.88,0.7,,0.621,T,l,0.75,0.2,1.032,,64.39,POH,-1.91667,0.168804,0.00587035,1.17898 kka2_1:4_S104T,kka2_1:4_104,Kka2,kka2_1:4,P00552,1.179,NO,104,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.436,-2.284,0.848,,0.536,T,A,0.27,-1.11,0.357,,63.64,HPP,-1.91433,0.168804,0.00555207,1.179 kka2_1:4_S204K,kka2_1:4_204,Kka2,kka2_1:4,P00552,1.179,NO,204,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.353,-3.511,2.158,,0.144,E,A,0.27,-1.2,2.442,,65.53,HPO,-0.953333,0.168804,0.00881794,1.179 kka2_1:8_V75I,kka2_1:8_75,Kka2,kka2_1:8,P00552,1.17904,NO,75,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-2.06,-1.939,-0.121,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.100394,0.00693733,1.17904 kka2_1:8_V75I,kka2_1:8_75,Kka2,kka2_1:8,P00552,1.17904,NO,75,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-2.06,-1.939,-0.121,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.100394,0.00693733,1.17904 beta-lactamase_0_L167I,beta-lactamase_0_167,TEM-1,beta-lactamase_0,P62593,1.17937,NO,167,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.138,-3.085,1.947,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.0500837,0.00303566,1.17937 kka2_1:4_V153C,kka2_1:4_153,Kka2,kka2_1:4,P00552,1.17944,NO,153,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.092,-4.724,3.632,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.168804,0.00501119,1.17944 kka2_1:8_T130M,kka2_1:8_130,Kka2,kka2_1:8,P00552,1.1795,NO,130,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.392,-3.607,1.215,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.100394,0.00804204,1.1795 kka2_1:8_T130M,kka2_1:8_130,Kka2,kka2_1:8,P00552,1.1795,NO,130,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.392,-3.607,1.215,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.100394,0.00804204,1.1795 kka2_1:4_D156A,kka2_1:4_156,Kka2,kka2_1:4,P00552,1.17952,NO,156,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.696,-2.256,0.56,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.168804,0.00926998,1.17952 kka2_1:2_G181S,kka2_1:2_181,Kka2,kka2_1:2,P00552,1.17953,NO,181,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-2.698,-2.485,-0.213,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.295029,0.00728319,1.17953 kka2_1:8_L53F,kka2_1:8_53,Kka2,kka2_1:8,P00552,1.17954,NO,53,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-2.681,-4.426,1.745,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.100394,0.00671168,1.17954 kka2_1:8_L53F,kka2_1:8_53,Kka2,kka2_1:8,P00552,1.17954,NO,53,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-2.681,-4.426,1.745,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.100394,0.00671168,1.17954 kka2_1:2_A9V,kka2_1:2_9,Kka2,kka2_1:2,P00552,1.17959,NO,9,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.079,-2.362,0.283,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.295029,0.00273264,1.17959 kka2_1:8_R44W,kka2_1:8_44,Kka2,kka2_1:8,P00552,1.17962,NO,44,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.062,-5.515,3.453,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.100394,0.00745043,1.17962 kka2_1:8_R44W,kka2_1:8_44,Kka2,kka2_1:8,P00552,1.17962,NO,44,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.062,-5.515,3.453,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.100394,0.00745043,1.17962 kka2_1:2_E86D,kka2_1:2_86,Kka2,kka2_1:2,P00552,1.17963,NO,86,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.86,-1.985,0.125,,0.369,.,B,1.04,1.92,3.573,,63.26,PAH,-1.98067,0.295029,0.00642858,1.17963 kka2_1:4_P98A,kka2_1:4_98,Kka2,kka2_1:4,P00552,1.1797,NO,98,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.526,-2.324,0.798,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.168804,0.00622754,1.1797 beta-lactamase_0_D271A,beta-lactamase_0_271,TEM-1,beta-lactamase_0,P62593,1.17971,NO,271,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.0500837,0.00752082,1.17971 beta-lactamase_0_V106H,beta-lactamase_0_106,TEM-1,beta-lactamase_0,P62593,1.17974,NO,106,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.218,-4.937,3.719,,0.258,T,A,0.44,0.24,0.952,,72.73,OHP,-1.04933,0.0500837,0.00304168,1.17974 kka2_1:8_I246C,kka2_1:8_246,Kka2,kka2_1:8,P00552,1.17978,NO,246,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-2.008,-4.975,2.967,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.100394,0.0139479,1.17978 kka2_1:8_I246C,kka2_1:8_246,Kka2,kka2_1:8,P00552,1.17978,NO,246,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-2.008,-4.975,2.967,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.100394,0.0139479,1.17978 kka2_1:8_Q4N,kka2_1:8_4,Kka2,kka2_1:8,P00552,1.17981,NO,4,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.361,-1.87,-0.491,,,,,,,2.026,,71.59,APA,-1.95533,0.100394,0.00239179,1.17981 kka2_1:8_Q4N,kka2_1:8_4,Kka2,kka2_1:8,P00552,1.17981,NO,4,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.361,-1.87,-0.491,,,,,,,2.026,,71.59,APA,-1.95533,0.100394,0.00239179,1.17981 kka2_1:8_H139L,kka2_1:8_139,Kka2,kka2_1:8,P00552,1.17982,NO,139,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-2.809,-2.514,-0.295,,0.471,H,A,0.17,0.68,28.583,28.583,63.64,BBB,-2.22,0.100394,0.00734779,1.17982 kka2_1:8_H139L,kka2_1:8_139,Kka2,kka2_1:8,P00552,1.17982,NO,139,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-2.809,-2.514,-0.295,,0.471,H,A,0.17,0.68,28.583,28.583,63.64,BBB,-2.22,0.100394,0.00734779,1.17982 beta-lactamase_0_K190A,beta-lactamase_0_190,TEM-1,beta-lactamase_0,P62593,1.17983,NO,190,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.994,-2.146,0.152,,0.371,H,A,2.34,0.16,16.606,16.606,77.62,BBH,-1.64167,0.0500837,0.00574527,1.17983 kka2_1:2_A13C,kka2_1:2_13,Kka2,kka2_1:2,P00552,1.17987,NO,13,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.248,-3.798,1.55,,0.689,G,A,0.46,0.99,,,92.05,OHH,-1.646,0.295029,0.00784241,1.17987 PSD95pdz3_P311Q,PSD95pdz3_311,PSD95pdz3,PSD95pdz3,P31016,1.17989,NO,311,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.236,-3.581,2.345,5.76649,,,,,14.78,,,,OOB,-1.409,0.0758425,0.0030796,1.17989 kka2_1:8_R173C,kka2_1:8_173,Kka2,kka2_1:8,P00552,1.1799,NO,173,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.407,-5.224,2.817,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.100394,0.00784999,1.1799 kka2_1:8_R173C,kka2_1:8_173,Kka2,kka2_1:8,P00552,1.1799,NO,173,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.407,-5.224,2.817,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.100394,0.00784999,1.1799 kka2_1:2_R18S,kka2_1:2_18,Kka2,kka2_1:2,P00552,1.17991,NO,18,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.055,-2.892,0.837,,0.474,T,A,1.2,0.54,8.405,8.405,71.59,ABH,-1.821,0.295029,0.00724065,1.17991 beta-lactamase_0_E26C,beta-lactamase_0_26,TEM-1,beta-lactamase_0,P62593,1.18,NO,26,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.454,-5.02,2.566,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.0500837,0.00297948,1.18 kka2_1:8_E230L,kka2_1:8_230,Kka2,kka2_1:8,P00552,1.18005,NO,230,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.672,-3.572,0.9,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.100394,0.00920051,1.18005 kka2_1:8_E230L,kka2_1:8_230,Kka2,kka2_1:8,P00552,1.18005,NO,230,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.672,-3.572,0.9,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.100394,0.00920051,1.18005 kka2_1:8_A166Q,kka2_1:8_166,Kka2,kka2_1:8,P00552,1.18009,NO,166,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.407,-3.207,0.8,,0.534,,B,1.04,1.03,13.995,13.995,71.59,HHO,-2.421,0.100394,0.00799912,1.18009 kka2_1:8_A166Q,kka2_1:8_166,Kka2,kka2_1:8,P00552,1.18009,NO,166,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.407,-3.207,0.8,,0.534,,B,1.04,1.03,13.995,13.995,71.59,HHO,-2.421,0.100394,0.00799912,1.18009 kka2_1:8_T225Q,kka2_1:8_225,Kka2,kka2_1:8,P00552,1.18009,NO,225,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.393,-3.262,0.869,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.100394,0.0113598,1.18009 kka2_1:8_T225Q,kka2_1:8_225,Kka2,kka2_1:8,P00552,1.18009,NO,225,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.393,-3.262,0.869,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.100394,0.0113598,1.18009 beta-lactamase_0_I285E,beta-lactamase_0_285,TEM-1,beta-lactamase_0,P62593,1.18012,NO,285,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.0500837,0.101555,1.18012 beta-lactamase_0_R202V,beta-lactamase_0_202,TEM-1,beta-lactamase_0,P62593,1.18013,NO,202,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.292,-3.679,2.387,,0.188,H,A,1.2,0.62,7.016,,77.62,PBP,-1.54767,0.0500837,0.00321899,1.18013 PSD95pdz3_H317K,PSD95pdz3_317,PSD95pdz3,PSD95pdz3,P31016,1.18015,NO,317,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-1.627,-3.139,1.512,6.19713,,,,,25.885,,,,HBB,-1.613,0.0758425,0.00111619,1.18015 kka2_1:8_G10A,kka2_1:8_10,Kka2,kka2_1:8,P00552,1.18016,NO,10,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.921,-3.11,1.189,,,,,,,1.862,,71.59,HOP,-2.10733,0.100394,0.00289233,1.18016 kka2_1:8_G10A,kka2_1:8_10,Kka2,kka2_1:8,P00552,1.18016,NO,10,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.921,-3.11,1.189,,,,,,,1.862,,71.59,HOP,-2.10733,0.100394,0.00289233,1.18016 kka2_1:4_L19I,kka2_1:4_19,Kka2,kka2_1:4,P00552,1.18021,NO,19,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.254,-2.338,1.084,,0.08,T,A,1.59,-0.26,2.645,,65.53,BHH,-2.221,0.168804,0.00620703,1.18021 WW_domain_S183K,WW_domain_183,Yap65,WW_domain,P46937,1.18031,NO,183,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.95,-3.372,1.422,5.35576,,,,,,1.594,,83.93,PPP,-1.48733,0.153962,0.00445513,1.18031 kka2_1:8_E96K,kka2_1:8_96,Kka2,kka2_1:8,P00552,1.18045,NO,96,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.573,-3.494,0.921,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.100394,0.00369441,1.18045 kka2_1:8_E96K,kka2_1:8_96,Kka2,kka2_1:8,P00552,1.18045,NO,96,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.573,-3.494,0.921,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.100394,0.00369441,1.18045 kka2_1:4_E231I,kka2_1:4_231,Kka2,kka2_1:4,P00552,1.18047,NO,231,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.002,-3.963,1.961,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.168804,0.00732383,1.18047 kka2_1:4_A255Q,kka2_1:4_255,Kka2,kka2_1:4,P00552,1.1805,NO,255,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.715,-4.01,2.295,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.168804,0.0126809,1.1805 kka2_1:4_E17A,kka2_1:4_17,Kka2,kka2_1:4,P00552,1.18051,NO,17,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.154,-2.316,0.162,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.168804,0.00688738,1.18051 kka2_1:8_K138S,kka2_1:8_138,Kka2,kka2_1:8,P00552,1.18055,NO,138,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-2.5,-2.62,0.12,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.100394,0.00628542,1.18055 kka2_1:8_K138S,kka2_1:8_138,Kka2,kka2_1:8,P00552,1.18055,NO,138,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-2.5,-2.62,0.12,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.100394,0.00628542,1.18055 kka2_1:8_A65Q,kka2_1:8_65,Kka2,kka2_1:8,P00552,1.18057,NO,65,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.744,-2.822,1.078,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.100394,0.00709258,1.18057 kka2_1:8_A65Q,kka2_1:8_65,Kka2,kka2_1:8,P00552,1.18057,NO,65,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.744,-2.822,1.078,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.100394,0.00709258,1.18057 kka2_1:2_Q26M,kka2_1:2_26,Kka2,kka2_1:2,P00552,1.18058,NO,26,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.18,-3.49,1.31,,0.448,E,B,0.4,0.44,5.022,,92.05,HPP,-2.11167,0.295029,0.00708962,1.18058 beta-lactamase_0_R220E,beta-lactamase_0_220,TEM-1,beta-lactamase_0,P62593,1.18066,NO,220,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-0.942,-3.264,2.322,,0.295,I,A,1.2,-0.76,21.573,21.573,74.48,HBP,-1.33633,0.0500837,0.00232421,1.18066 PSD95pdz3_P311G,PSD95pdz3_311,PSD95pdz3,PSD95pdz3,P31016,1.18069,NO,311,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.236,-3.04,1.804,5.76649,,,,,14.78,,,,OOB,-1.409,0.0758425,0.0030796,1.18069 beta-lactamase_0_K254D,beta-lactamase_0_254,TEM-1,beta-lactamase_0,P62593,1.18075,NO,254,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-2.126,,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.0500837,0.00369,1.18075 kka2_1:2_Q42T,kka2_1:2_42,Kka2,kka2_1:2,P00552,1.18075,NO,42,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.907,-2.915,0.008,,1.044,T,B,0.64,-0.8,2.792,,71.59,HPO,-2.12433,0.295029,0.00679212,1.18075 kka2_1:8_A110N,kka2_1:8_110,Kka2,kka2_1:8,P00552,1.18075,NO,110,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.064,-3.944,1.88,,0.175,H,A,1.04,-1.19,11.413,11.413,71.59,OHA,-1.91867,0.100394,0.00759851,1.18075 kka2_1:8_A110N,kka2_1:8_110,Kka2,kka2_1:8,P00552,1.18075,NO,110,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.064,-3.944,1.88,,0.175,H,A,1.04,-1.19,11.413,11.413,71.59,OHA,-1.91867,0.100394,0.00759851,1.18075 kka2_1:8_M178C,kka2_1:8_178,Kka2,kka2_1:8,P00552,1.18077,NO,178,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-3.206,-3.246,0.04,,0.554,,b,1.59,0.68,13.268,13.268,71.59,BHO,-2.154,0.100394,0.00717253,1.18077 kka2_1:8_M178C,kka2_1:8_178,Kka2,kka2_1:8,P00552,1.18077,NO,178,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-3.206,-3.246,0.04,,0.554,,b,1.59,0.68,13.268,13.268,71.59,BHO,-2.154,0.100394,0.00717253,1.18077 kka2_1:4_D157Q,kka2_1:4_157,Kka2,kka2_1:4,P00552,1.18091,NO,157,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.993,-3.78,2.787,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.168804,0.0042313,1.18091 kka2_1:8_V75H,kka2_1:8_75,Kka2,kka2_1:8,P00552,1.181,NO,75,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-2.06,-4.952,2.892,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.100394,0.00693733,1.181 kka2_1:8_V75H,kka2_1:8_75,Kka2,kka2_1:8,P00552,1.181,NO,75,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-2.06,-4.952,2.892,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.100394,0.00693733,1.181 beta-lactamase_0_R41I,beta-lactamase_0_41,TEM-1,beta-lactamase_0,P62593,1.18102,NO,41,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-0.942,-4.008,3.066,,0.321,E,B,1.2,-0.07,2.68,,65.03,HBH,-1.30267,0.0500837,0.00123327,1.18102 beta-lactamase_0_I244P,beta-lactamase_0_244,TEM-1,beta-lactamase_0,P62593,1.18103,NO,244,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.555,-4.01,2.455,,,E,B,0.48,-0.84,1.241,,77.62,OHH,-1.385,0.0500837,0.00605379,1.18103 beta-lactamase_0_L49W,beta-lactamase_0_49,TEM-1,beta-lactamase_0,P62593,1.18107,NO,49,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.897,-5.315,3.418,,0.131,T,A,0.55,0.04,13.838,13.838,64.69,AHP,-1.99233,0.0500837,0.00401477,1.18107 kka2_1:4_A166K,kka2_1:4_166,Kka2,kka2_1:4,P00552,1.18118,NO,166,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.407,-3.569,1.162,,0.534,.,B,0.46,1.03,,,71.59,HHO,-2.421,0.168804,0.00799912,1.18118 kka2_1:8_T146M,kka2_1:8_146,Kka2,kka2_1:8,P00552,1.18138,NO,146,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.978,-3.5,0.522,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.100394,0.00606474,1.18138 kka2_1:8_T146M,kka2_1:8_146,Kka2,kka2_1:8,P00552,1.18138,NO,146,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.978,-3.5,0.522,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.100394,0.00606474,1.18138 kka2_1:4_D180C,kka2_1:4_180,Kka2,kka2_1:4,P00552,1.18145,NO,180,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.416,-5.213,2.797,,1.03,S,a,0.29,1.5,14.668,14.668,71.59,OAO,-2.02933,0.168804,0.00756412,1.18145 kka2_1:8_D250S,kka2_1:8_250,Kka2,kka2_1:8,P00552,1.18148,NO,250,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.015,-2.641,1.626,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.100394,0.0177103,1.18148 kka2_1:8_D250S,kka2_1:8_250,Kka2,kka2_1:8,P00552,1.18148,NO,250,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.015,-2.641,1.626,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.100394,0.0177103,1.18148 kka2_1:8_E199V,kka2_1:8_199,Kka2,kka2_1:8,P00552,1.18162,NO,199,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.234,-2.91,0.676,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.100394,0.00854122,1.18162 kka2_1:8_E199V,kka2_1:8_199,Kka2,kka2_1:8,P00552,1.18162,NO,199,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.234,-2.91,0.676,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.100394,0.00854122,1.18162 kka2_1:8_Q163N,kka2_1:8_163,Kka2,kka2_1:8,P00552,1.18165,NO,163,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.162,-3.939,1.777,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.100394,0.00719507,1.18165 kka2_1:8_Q163N,kka2_1:8_163,Kka2,kka2_1:8,P00552,1.18165,NO,163,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.162,-3.939,1.777,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.100394,0.00719507,1.18165 beta-lactamase_0_I280V,beta-lactamase_0_280,TEM-1,beta-lactamase_0,P62593,1.18166,NO,280,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.0500837,0.0530888,1.18166 kka2_1:4_A172I,kka2_1:4_172,Kka2,kka2_1:4,P00552,1.18166,NO,172,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.757,-3.215,1.458,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.168804,0.0079265,1.18166 kka2_1:8_E231H,kka2_1:8_231,Kka2,kka2_1:8,P00552,1.18176,NO,231,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.002,-4.353,2.351,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.100394,0.00732383,1.18176 kka2_1:8_E231H,kka2_1:8_231,Kka2,kka2_1:8,P00552,1.18176,NO,231,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.002,-4.353,2.351,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.100394,0.00732383,1.18176 kka2_1:8_T73A,kka2_1:8_73,Kka2,kka2_1:8,P00552,1.18181,NO,73,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.51,-2.502,-0.008,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.100394,0.00628605,1.18181 kka2_1:8_T73A,kka2_1:8_73,Kka2,kka2_1:8,P00552,1.18181,NO,73,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.51,-2.502,-0.008,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.100394,0.00628605,1.18181 kka2_1:4_A110D,kka2_1:4_110,Kka2,kka2_1:4,P00552,1.18183,NO,110,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.064,-2.796,0.732,,0.175,H,A,0.46,-1.19,23.237,23.237,71.59,OHA,-1.91867,0.168804,0.00759851,1.18183 beta-lactamase_0_E238C,beta-lactamase_0_238,TEM-1,beta-lactamase_0,P62593,1.18194,NO,238,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.0500837,0.00743256,1.18194 kka2_1:4_E231A,kka2_1:4_231,Kka2,kka2_1:4,P00552,1.18195,NO,231,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.002,-3.339,1.337,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.168804,0.00732383,1.18195 kka2_1:8_R44E,kka2_1:8_44,Kka2,kka2_1:8,P00552,1.18208,NO,44,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.062,-2.778,0.716,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.100394,0.00745043,1.18208 kka2_1:8_R44E,kka2_1:8_44,Kka2,kka2_1:8,P00552,1.18208,NO,44,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.062,-2.778,0.716,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.100394,0.00745043,1.18208 kka2_1:2_E17A,kka2_1:2_17,Kka2,kka2_1:2,P00552,1.18209,NO,17,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.154,-2.316,0.162,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.295029,0.00688738,1.18209 beta-lactamase_0_V29C,beta-lactamase_0_29,TEM-1,beta-lactamase_0,P62593,1.18214,NO,29,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-2.856,-5.117,2.261,,0.733,H,A,0.44,-0.78,21.916,21.916,93.01,HHB,-2.24733,0.0500837,0.00318969,1.18214 kka2_1:8_V49A,kka2_1:8_49,Kka2,kka2_1:8,P00552,1.18214,NO,49,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.614,-2.584,0.97,,,E,B,1.48,-0.77,1.31,,64.39,HHB,-1.3,0.100394,0.00615685,1.18214 kka2_1:8_V49A,kka2_1:8_49,Kka2,kka2_1:8,P00552,1.18214,NO,49,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.614,-2.584,0.97,,,E,B,1.48,-0.77,1.31,,64.39,HHB,-1.3,0.100394,0.00615685,1.18214 kka2_1:8_Q26M,kka2_1:8_26,Kka2,kka2_1:8,P00552,1.18217,NO,26,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.18,-3.49,1.31,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.100394,0.00708962,1.18217 kka2_1:8_Q26M,kka2_1:8_26,Kka2,kka2_1:8,P00552,1.18217,NO,26,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.18,-3.49,1.31,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.100394,0.00708962,1.18217 kka2_1:4_M1L,kka2_1:4_1,Kka2,kka2_1:4,P00552,1.18223,NO,1,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.787,-2.339,0.552,,,,,,,1.347,,62.12,NAHH,-1.787,0.168804,0.00251939,1.18223 kka2_1:2_A176N,kka2_1:2_176,Kka2,kka2_1:2,P00552,1.18225,NO,176,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.621,-3.03,1.409,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.295029,0.0083587,1.18225 beta-lactamase_0_I258A,beta-lactamase_0_258,TEM-1,beta-lactamase_0,P62593,1.18226,NO,258,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.0500837,0.007931,1.18226 kka2_1:8_D250K,kka2_1:8_250,Kka2,kka2_1:8,P00552,1.18226,NO,250,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.015,-3.438,2.423,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.100394,0.0177103,1.18226 kka2_1:8_D250K,kka2_1:8_250,Kka2,kka2_1:8,P00552,1.18226,NO,250,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.015,-3.438,2.423,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.100394,0.0177103,1.18226 kka2_1:2_S204T,kka2_1:2_204,Kka2,kka2_1:2,P00552,1.18231,NO,204,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.353,-1.747,0.394,,0.144,E,A,0.27,-1.2,2.442,,65.53,HPO,-0.953333,0.295029,0.00881794,1.18231 kka2_1:2_G10E,kka2_1:2_10,Kka2,kka2_1:2,P00552,1.18235,NO,10,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.921,-2.456,0.535,,,,,,,2.192,,71.59,HOP,-2.10733,0.295029,0.00289233,1.18235 kka2_1:8_T72F,kka2_1:8_72,Kka2,kka2_1:8,P00552,1.18238,NO,72,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.38,-4.46,2.08,,0.784,H,A,0.22,0.29,3.603,,65.53,HPP,-2.238,0.100394,0.00750756,1.18238 kka2_1:8_T72F,kka2_1:8_72,Kka2,kka2_1:8,P00552,1.18238,NO,72,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.38,-4.46,2.08,,0.784,H,A,0.22,0.29,3.603,,65.53,HPP,-2.238,0.100394,0.00750756,1.18238 kka2_1:8_G181I,kka2_1:8_181,Kka2,kka2_1:8,P00552,1.18239,NO,181,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-2.698,-3.104,0.406,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.100394,0.00728319,1.18239 kka2_1:8_G181I,kka2_1:8_181,Kka2,kka2_1:8,P00552,1.18239,NO,181,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-2.698,-3.104,0.406,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.100394,0.00728319,1.18239 kka2_1:8_E142L,kka2_1:8_142,Kka2,kka2_1:8,P00552,1.18248,NO,142,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.221,-3.056,0.835,,0.471,H,A,1.04,0.85,2.655,,65.53,HAB,-2.08033,0.100394,0.00748883,1.18248 kka2_1:8_E142L,kka2_1:8_142,Kka2,kka2_1:8,P00552,1.18248,NO,142,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.221,-3.056,0.835,,0.471,H,A,1.04,0.85,2.655,,65.53,HAB,-2.08033,0.100394,0.00748883,1.18248 beta-lactamase_0_T179M,beta-lactamase_0_179,TEM-1,beta-lactamase_0,P62593,1.18251,NO,179,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.085,-4.564,3.479,,,E,B,0.22,-1.38,0.367,,73.08,PPH,-1.557,0.0500837,0.00226045,1.18251 kka2_1:8_E149R,kka2_1:8_149,Kka2,kka2_1:8,P00552,1.18264,NO,149,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.994,-2.471,0.477,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.100394,0.00803343,1.18264 kka2_1:8_E149R,kka2_1:8_149,Kka2,kka2_1:8,P00552,1.18264,NO,149,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.994,-2.471,0.477,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.100394,0.00803343,1.18264 kka2_1:8_Q42R,kka2_1:8_42,Kka2,kka2_1:8,P00552,1.18266,NO,42,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.907,-3.056,0.149,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.100394,0.00679212,1.18266 kka2_1:8_Q42R,kka2_1:8_42,Kka2,kka2_1:8,P00552,1.18266,NO,42,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.907,-3.056,0.149,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.100394,0.00679212,1.18266 kka2_1:4_C77G,kka2_1:4_77,Kka2,kka2_1:4,P00552,1.18277,NO,77,C,G,CG,Special,Special,5.07,3.29388,-1.77612,159,121,75,-46,108.5,60.1,-48.4,-1.477,-2.097,0.62,,0.229,B,b,0.46,-0.57,2.499,,63.26,OOH,-1.55667,0.168804,0.00441216,1.18277 kka2_1:8_A110W,kka2_1:8_110,Kka2,kka2_1:8,P00552,1.18286,NO,110,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.064,-5.542,3.478,,0.175,H,A,1.04,-1.19,11.413,11.413,71.59,OHA,-1.91867,0.100394,0.00759851,1.18286 kka2_1:8_A110W,kka2_1:8_110,Kka2,kka2_1:8,P00552,1.18286,NO,110,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.064,-5.542,3.478,,0.175,H,A,1.04,-1.19,11.413,11.413,71.59,OHA,-1.91867,0.100394,0.00759851,1.18286 kka2_1:8_L165E,kka2_1:8_165,Kka2,kka2_1:8,P00552,1.18289,NO,165,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-2.453,-2.802,0.349,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.100394,0.00801161,1.18289 kka2_1:8_L165E,kka2_1:8_165,Kka2,kka2_1:8,P00552,1.18289,NO,165,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-2.453,-2.802,0.349,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.100394,0.00801161,1.18289 kka2_1:8_G6F,kka2_1:8_6,Kka2,kka2_1:8,P00552,1.18305,NO,6,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.685,-4.169,2.484,,,,,,,,,71.59,AOH,-1.639,0.100394,0.00204693,1.18305 kka2_1:8_G6F,kka2_1:8_6,Kka2,kka2_1:8,P00552,1.18305,NO,6,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.685,-4.169,2.484,,,,,,,,,71.59,AOH,-1.639,0.100394,0.00204693,1.18305 kka2_1:2_A172L,kka2_1:2_172,Kka2,kka2_1:2,P00552,1.18313,NO,172,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.757,-2.996,1.239,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.295029,0.0079265,1.18313 beta-lactamase_0_E108R,beta-lactamase_0_108,TEM-1,beta-lactamase_0,P62593,1.18316,NO,108,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.46,-2.885,1.425,,0.572,G,A,1.04,1.87,8.602,8.602,72.73,PAB,-1.437,0.0500837,0.00413372,1.18316 beta-lactamase_0_K190S,beta-lactamase_0_190,TEM-1,beta-lactamase_0,P62593,1.18322,NO,190,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.994,-2.653,0.659,,0.371,H,A,2.34,0.16,16.606,16.606,77.62,BBH,-1.64167,0.0500837,0.00574527,1.18322 kka2_1:4_S204V,kka2_1:4_204,Kka2,kka2_1:4,P00552,1.18322,NO,204,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.353,-3.451,2.098,,0.144,E,A,0.27,-1.2,2.442,,65.53,HPO,-0.953333,0.168804,0.00881794,1.18322 kka2_1:8_L243H,kka2_1:8_243,Kka2,kka2_1:8,P00552,1.18326,NO,243,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-2.651,-3.263,0.612,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.100394,0.00884927,1.18326 kka2_1:8_L243H,kka2_1:8_243,Kka2,kka2_1:8,P00552,1.18326,NO,243,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-2.651,-3.263,0.612,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.100394,0.00884927,1.18326 kka2_1:4_G181R,kka2_1:4_181,Kka2,kka2_1:4,P00552,1.18327,NO,181,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-2.698,-2.623,-0.075,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.168804,0.00728319,1.18327 kka2_1:2_T130I,kka2_1:2_130,Kka2,kka2_1:2,P00552,1.18331,NO,130,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.392,-3.995,1.603,,0.561,G,A,0.22,0.77,0.5,,92.05,HPO,-1.62633,0.295029,0.00804204,1.18331 kka2_1:2_A13F,kka2_1:2_13,Kka2,kka2_1:2,P00552,1.18333,NO,13,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.248,-4.439,2.191,,0.689,G,A,0.46,0.99,,,92.05,OHH,-1.646,0.295029,0.00784241,1.18333 beta-lactamase_0_A225D,beta-lactamase_0_225,TEM-1,beta-lactamase_0,P62593,1.18338,NO,225,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.845,-2.561,0.716,,1,T,B,0.46,-0.38,11.722,11.722,74.48,OHO,-1.39967,0.0500837,0.00465057,1.18338 beta-lactamase_0_A246E,beta-lactamase_0_246,TEM-1,beta-lactamase_0,P62593,1.18338,NO,246,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.121,-3.906,1.785,,0.01,E,B,0.46,-1.01,1.201,,73.78,HHH,-1.55633,0.0500837,0.00569458,1.18338 kka2_1:8_F20S,kka2_1:8_20,Kka2,kka2_1:8,P00552,1.18341,NO,20,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-3.354,-2.147,-1.207,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.100394,0.00701744,1.18341 kka2_1:8_F20S,kka2_1:8_20,Kka2,kka2_1:8,P00552,1.18341,NO,20,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-3.354,-2.147,-1.207,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.100394,0.00701744,1.18341 kka2_1:4_A247W,kka2_1:4_247,Kka2,kka2_1:4,P00552,1.18353,NO,247,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.459,-5.465,3.006,,1.01,S,A,0.46,0.65,,,92.05,HHH,-2.197,0.168804,0.0102428,1.18353 kka2_1:8_Q100M,kka2_1:8_100,Kka2,kka2_1:8,P00552,1.18353,NO,100,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.77,-3.639,0.869,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.100394,0.0066405,1.18353 kka2_1:8_Q100M,kka2_1:8_100,Kka2,kka2_1:8,P00552,1.18353,NO,100,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.77,-3.639,0.869,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.100394,0.0066405,1.18353 kka2_1:8_A25M,kka2_1:8_25,Kka2,kka2_1:8,P00552,1.18355,NO,25,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.496,-3.529,1.033,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.100394,0.00595636,1.18355 kka2_1:8_A25M,kka2_1:8_25,Kka2,kka2_1:8,P00552,1.18355,NO,25,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.496,-3.529,1.033,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.100394,0.00595636,1.18355 beta-lactamase_0_S80D,beta-lactamase_0_80,TEM-1,beta-lactamase_0,P62593,1.18372,NO,80,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.029,-2.7,0.671,,0.192,H,A,0.27,0.46,12.403,12.403,77.62,HPB,-1.44567,0.0500837,0.00565569,1.18372 kka2_1:8_S11C,kka2_1:8_11,Kka2,kka2_1:8,P00552,1.18376,NO,11,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.322,-4.711,2.389,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.100394,0.00381691,1.18376 kka2_1:8_S11C,kka2_1:8_11,Kka2,kka2_1:8,P00552,1.18376,NO,11,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.322,-4.711,2.389,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.100394,0.00381691,1.18376 beta-lactamase_0_I258G,beta-lactamase_0_258,TEM-1,beta-lactamase_0,P62593,1.18378,NO,258,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.0500837,0.007931,1.18378 kka2_1:4_A25W,kka2_1:4_25,Kka2,kka2_1:4,P00552,1.18378,NO,25,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.496,-5.529,3.033,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.168804,0.00595636,1.18378 kka2_1:4_D180F,kka2_1:4_180,Kka2,kka2_1:4,P00552,1.18378,NO,180,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.416,-4.402,1.986,,1.03,S,a,0.29,1.5,14.668,14.668,71.59,OAO,-2.02933,0.168804,0.00756412,1.18378 kka2_1:8_V16D,kka2_1:8_16,Kka2,kka2_1:8,P00552,1.18379,NO,16,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-3.087,-2.706,-0.381,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.100394,0.00694011,1.18379 kka2_1:8_V16D,kka2_1:8_16,Kka2,kka2_1:8,P00552,1.18379,NO,16,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-3.087,-2.706,-0.381,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.100394,0.00694011,1.18379 kka2_1:4_R44M,kka2_1:4_44,Kka2,kka2_1:4,P00552,1.18381,NO,44,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.062,-4.711,2.649,,0.487,S,B,1.2,-0.35,5.71,,71.59,OBO,-1.80767,0.168804,0.00745043,1.18381 kka2_1:4_R202M,kka2_1:4_202,Kka2,kka2_1:4,P00552,1.18385,NO,202,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.761,-4.784,3.023,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.168804,0.00696498,1.18385 kka2_1:8_R38K,kka2_1:8_38,Kka2,kka2_1:8,P00552,1.18385,NO,38,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.207,-3.15,1.943,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.100394,0.00372499,1.18385 kka2_1:8_R38K,kka2_1:8_38,Kka2,kka2_1:8,P00552,1.18385,NO,38,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.207,-3.15,1.943,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.100394,0.00372499,1.18385 kka2_1:8_T130K,kka2_1:8_130,Kka2,kka2_1:8,P00552,1.18387,NO,130,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.392,-3.096,0.704,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.100394,0.00804204,1.18387 kka2_1:8_T130K,kka2_1:8_130,Kka2,kka2_1:8,P00552,1.18387,NO,130,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.392,-3.096,0.704,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.100394,0.00804204,1.18387 kka2_1:2_L7R,kka2_1:2_7,Kka2,kka2_1:2,P00552,1.1839,NO,7,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.926,-3.722,1.796,,,,,,,3.012,,71.59,OHB,-2.12333,0.295029,0.00269456,1.1839 kka2_1:8_A13I,kka2_1:8_13,Kka2,kka2_1:8,P00552,1.18398,NO,13,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.248,-3.155,0.907,,0.689,G,A,1.04,0.99,14.966,14.966,92.05,OHH,-1.646,0.100394,0.00784241,1.18398 kka2_1:8_A13I,kka2_1:8_13,Kka2,kka2_1:8,P00552,1.18398,NO,13,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.248,-3.155,0.907,,0.689,G,A,1.04,0.99,14.966,14.966,92.05,OHH,-1.646,0.100394,0.00784241,1.18398 kka2_1:4_A79C,kka2_1:4_79,Kka2,kka2_1:4,P00552,1.18413,NO,79,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.368,-5.212,2.844,,0.563,.,B,0.46,-0.43,2.291,,71.59,HHH,-1.752,0.168804,0.00664821,1.18413 beta-lactamase_0_F70H,beta-lactamase_0_70,TEM-1,beta-lactamase_0,P62593,1.18415,NO,70,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.169,-4.494,3.325,,,H,A,0.58,-1.34,2.153,,63.99,PHB,-0.980667,0.0500837,0.00193499,1.18415 beta-lactamase_0_T269C,beta-lactamase_0_269,TEM-1,beta-lactamase_0,P62593,1.18423,NO,269,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.156,,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.0500837,0.00950944,1.18423 kka2_1:4_E149R,kka2_1:4_149,Kka2,kka2_1:4,P00552,1.18432,NO,149,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.994,-2.471,0.477,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.168804,0.00803343,1.18432 kka2_1:8_D118H,kka2_1:8_118,Kka2,kka2_1:8,P00552,1.18435,NO,118,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.07,-3.064,0.994,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.100394,0.0067852,1.18435 kka2_1:8_D118H,kka2_1:8_118,Kka2,kka2_1:8,P00552,1.18435,NO,118,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.07,-3.064,0.994,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.100394,0.0067852,1.18435 kka2_1:8_A172Y,kka2_1:8_172,Kka2,kka2_1:8,P00552,1.18439,NO,172,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.757,-4.449,2.692,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.100394,0.0079265,1.18439 kka2_1:8_A172Y,kka2_1:8_172,Kka2,kka2_1:8,P00552,1.18439,NO,172,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.757,-4.449,2.692,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.100394,0.0079265,1.18439 kka2_1:8_E17L,kka2_1:8_17,Kka2,kka2_1:8,P00552,1.18442,NO,17,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.154,-3.123,0.969,,0.957,T,A,1.04,0.22,31.483,31.483,63.64,HAB,-2.432,0.100394,0.00688738,1.18442 kka2_1:8_E17L,kka2_1:8_17,Kka2,kka2_1:8,P00552,1.18442,NO,17,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.154,-3.123,0.969,,0.957,T,A,1.04,0.22,31.483,31.483,63.64,HAB,-2.432,0.100394,0.00688738,1.18442 beta-lactamase_0_V29F,beta-lactamase_0_29,TEM-1,beta-lactamase_0,P62593,1.18455,NO,29,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-2.856,-4.364,1.508,,0.733,H,A,0.44,-0.78,21.916,21.916,93.01,HHB,-2.24733,0.0500837,0.00318969,1.18455 kka2_1:4_P249I,kka2_1:4_249,Kka2,kka2_1:4,P00552,1.18455,NO,249,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.867,-2.381,0.514,,0.406,.,B,0.52,-0.01,,,92.05,HOA,-1.66867,0.168804,0.011045,1.18455 kka2_1:8_T85A,kka2_1:8_85,Kka2,kka2_1:8,P00552,1.18459,NO,85,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.165,-2.833,0.668,,0.576,E,B,0.22,1.39,22.154,22.154,71.59,HPA,-2.10133,0.100394,0.00634493,1.18459 kka2_1:8_T85A,kka2_1:8_85,Kka2,kka2_1:8,P00552,1.18459,NO,85,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.165,-2.833,0.668,,0.576,E,B,0.22,1.39,22.154,22.154,71.59,HPA,-2.10133,0.100394,0.00634493,1.18459 beta-lactamase_0_T131Q,beta-lactamase_0_131,TEM-1,beta-lactamase_0,P62593,1.1846,NO,131,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.328,-3.951,2.623,,,H,A,0.22,-0.69,3.306,,67.48,PPH,-1.00867,0.0500837,0.00345886,1.1846 kka2_1:2_A150M,kka2_1:2_150,Kka2,kka2_1:2,P00552,1.18469,NO,150,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.949,-4.623,3.674,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.295029,0.0045009,1.18469 beta-lactamase_0_E87R,beta-lactamase_0_87,TEM-1,beta-lactamase_0,P62593,1.18478,NO,87,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.421,-3.739,2.318,,0.048,,B,1.04,0.92,1.159,,64.69,PAP,-1.969,0.0500837,0.00337888,1.18478 kka2_1:4_G6T,kka2_1:4_6,Kka2,kka2_1:4,P00552,1.18478,NO,6,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.685,-3.379,1.694,,,,,,,,,71.59,AOH,-1.639,0.168804,0.00204693,1.18478 kka2_1:4_P76N,kka2_1:4_76,Kka2,kka2_1:4,P00552,1.18489,NO,76,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.449,-3.923,2.474,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.168804,0.00625685,1.18489 kka2_1:8_G43D,kka2_1:8_43,Kka2,kka2_1:8,P00552,1.18491,NO,43,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.587,-2.025,0.438,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.100394,0.0071925,1.18491 kka2_1:8_G43D,kka2_1:8_43,Kka2,kka2_1:8,P00552,1.18491,NO,43,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.587,-2.025,0.438,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.100394,0.0071925,1.18491 kka2_1:2_A108Q,kka2_1:2_108,Kka2,kka2_1:2,P00552,1.18492,NO,108,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.061,-3.285,1.224,,0.243,.,B,0.46,-1.34,2.462,,71.59,HHO,-1.57033,0.295029,0.00751209,1.18492 kka2_1:8_T73R,kka2_1:8_73,Kka2,kka2_1:8,P00552,1.18492,NO,73,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.51,-2.766,0.256,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.100394,0.00628605,1.18492 kka2_1:8_T73R,kka2_1:8_73,Kka2,kka2_1:8,P00552,1.18492,NO,73,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.51,-2.766,0.256,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.100394,0.00628605,1.18492 kka2_1:4_E111A,kka2_1:4_111,Kka2,kka2_1:4,P00552,1.18493,NO,111,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.28,-2.356,0.076,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.168804,0.00746789,1.18493 beta-lactamase_0_T131N,beta-lactamase_0_131,TEM-1,beta-lactamase_0,P62593,1.18495,NO,131,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.328,-3.603,2.275,,,H,A,0.22,-0.69,3.306,,67.48,PPH,-1.00867,0.0500837,0.00345886,1.18495 kka2_1:4_V198T,kka2_1:4_198,Kka2,kka2_1:4,P00552,1.18496,NO,198,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.719,-2.237,0.518,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.168804,0.00835002,1.18496 kka2_1:8_V83C,kka2_1:8_83,Kka2,kka2_1:8,P00552,1.18496,NO,83,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-2.567,-5.124,2.557,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.100394,0.00650486,1.18496 kka2_1:8_V83C,kka2_1:8_83,Kka2,kka2_1:8,P00552,1.18496,NO,83,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-2.567,-5.124,2.557,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.100394,0.00650486,1.18496 kka2_1:8_T72Q,kka2_1:8_72,Kka2,kka2_1:8,P00552,1.18507,NO,72,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.38,-2.662,0.282,,0.784,H,A,0.22,0.29,3.603,,65.53,HPP,-2.238,0.100394,0.00750756,1.18507 kka2_1:8_T72Q,kka2_1:8_72,Kka2,kka2_1:8,P00552,1.18507,NO,72,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.38,-2.662,0.282,,0.784,H,A,0.22,0.29,3.603,,65.53,HPP,-2.238,0.100394,0.00750756,1.18507 beta-lactamase_0_G236D,beta-lactamase_0_236,TEM-1,beta-lactamase_0,P62593,1.1851,NO,236,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.784,-3.513,2.729,,0.241,,b,0.29,-0.59,3.506,,64.69,HOO,-1.025,0.0500837,0.00162372,1.1851 kka2_1:2_Q155R,kka2_1:2_155,Kka2,kka2_1:2,P00552,1.18516,NO,155,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.606,-3.728,1.122,,0.525,T,A,0.64,1.49,1.592,,63.64,APA,-1.726,0.295029,0.00641853,1.18516 beta-lactamase_0_M153W,beta-lactamase_0_153,TEM-1,beta-lactamase_0,P62593,1.18518,NO,153,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-3.193,-5.376,2.183,,0.14,T,A,0.55,-0.11,3.826,,77.62,PHO,-2.25767,0.0500837,0.00509109,1.18518 kka2_1:2_G6V,kka2_1:2_6,Kka2,kka2_1:2,P00552,1.18518,NO,6,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.685,-3.428,1.743,,,,,,,,,71.59,AOH,-1.639,0.295029,0.00204693,1.18518 kka2_1:4_Q26H,kka2_1:4_26,Kka2,kka2_1:4,P00552,1.18535,NO,26,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.18,-3.435,1.255,,0.448,E,B,0.4,0.44,5.022,,92.05,HPP,-2.11167,0.168804,0.00708962,1.18535 kka2_1:8_D180T,kka2_1:8_180,Kka2,kka2_1:8,P00552,1.18547,NO,180,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.416,-3.001,0.585,,1.03,S,a,0.75,1.5,14.668,14.668,71.59,OAO,-2.02933,0.100394,0.00756412,1.18547 kka2_1:8_D180T,kka2_1:8_180,Kka2,kka2_1:8,P00552,1.18547,NO,180,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.416,-3.001,0.585,,1.03,S,a,0.75,1.5,14.668,14.668,71.59,OAO,-2.02933,0.100394,0.00756412,1.18547 kka2_1:8_E149K,kka2_1:8_149,Kka2,kka2_1:8,P00552,1.18547,NO,149,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.994,-2.785,0.791,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.100394,0.00803343,1.18547 kka2_1:8_E149K,kka2_1:8_149,Kka2,kka2_1:8,P00552,1.18547,NO,149,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.994,-2.785,0.791,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.100394,0.00803343,1.18547 kka2_1:4_A79D,kka2_1:4_79,Kka2,kka2_1:4,P00552,1.18561,NO,79,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.368,-2.473,0.105,,0.563,.,B,0.46,-0.43,2.291,,71.59,HHH,-1.752,0.168804,0.00664821,1.18561 kka2_1:4_N200E,kka2_1:4_200,Kka2,kka2_1:4,P00552,1.18572,NO,200,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-2.446,-2.236,-0.21,,0.756,T,L,0.61,-0.08,1.746,,64.39,APO,-2.08,0.168804,0.00838549,1.18572 beta-lactamase_0_Q86N,beta-lactamase_0_86,TEM-1,beta-lactamase_0,P62593,1.18573,NO,86,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.4,-3.754,1.354,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.0500837,0.00450027,1.18573 kka2_1:8_A168H,kka2_1:8_168,Kka2,kka2_1:8,P00552,1.18573,NO,168,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.989,-3.256,1.267,,0.67,H,A,0.46,0.15,11.329,11.329,64.39,OHA,-2.12933,0.100394,0.00806773,1.18573 kka2_1:8_A168H,kka2_1:8_168,Kka2,kka2_1:8,P00552,1.18573,NO,168,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.989,-3.256,1.267,,0.67,H,A,0.46,0.15,11.329,11.329,64.39,OHA,-2.12933,0.100394,0.00806773,1.18573 kka2_1:8_Q26W,kka2_1:8_26,Kka2,kka2_1:8,P00552,1.18577,NO,26,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.18,-5.501,3.321,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.100394,0.00708962,1.18577 kka2_1:8_Q26W,kka2_1:8_26,Kka2,kka2_1:8,P00552,1.18577,NO,26,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.18,-5.501,3.321,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.100394,0.00708962,1.18577 kka2_1:8_T146F,kka2_1:8_146,Kka2,kka2_1:8,P00552,1.18582,NO,146,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.978,-4.333,1.355,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.100394,0.00606474,1.18582 kka2_1:8_T146F,kka2_1:8_146,Kka2,kka2_1:8,P00552,1.18582,NO,146,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.978,-4.333,1.355,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.100394,0.00606474,1.18582 kka2_1:2_G95R,kka2_1:2_95,Kka2,kka2_1:2,P00552,1.18583,NO,95,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-2.403,-3.111,0.708,,0.126,E,B,0.29,-0.74,0.359,,71.59,HOA,-2.198,0.295029,0.00743616,1.18583 kka2_1:2_M178T,kka2_1:2_178,Kka2,kka2_1:2,P00552,1.18597,NO,178,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-3.206,-3.644,0.438,,0.554,.,b,0.55,0.68,3.152,,71.59,BHO,-2.154,0.295029,0.00717253,1.18597 kka2_1:8_A13C,kka2_1:8_13,Kka2,kka2_1:8,P00552,1.18597,NO,13,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.248,-3.798,1.55,,0.689,G,A,1.04,0.99,14.966,14.966,92.05,OHH,-1.646,0.100394,0.00784241,1.18597 kka2_1:8_A13C,kka2_1:8_13,Kka2,kka2_1:8,P00552,1.18597,NO,13,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.248,-3.798,1.55,,0.689,G,A,1.04,0.99,14.966,14.966,92.05,OHH,-1.646,0.100394,0.00784241,1.18597 kka2_1:8_K138Y,kka2_1:8_138,Kka2,kka2_1:8,P00552,1.18597,NO,138,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-2.5,-4.407,1.907,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.100394,0.00628542,1.18597 kka2_1:8_K138Y,kka2_1:8_138,Kka2,kka2_1:8,P00552,1.18597,NO,138,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-2.5,-4.407,1.907,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.100394,0.00628542,1.18597 PSD95pdz3_E334F,PSD95pdz3_334,PSD95pdz3,PSD95pdz3,P31016,1.1861,NO,334,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.404,-3.974,2.57,5.60175,,,,,53.09,,,,OAO,-1.14,0.0758425,0.000912998,1.1861 kka2_1:8_D227S,kka2_1:8_227,Kka2,kka2_1:8,P00552,1.18613,NO,227,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.758,-1.053,-0.705,,0.128,H,A,0.75,-0.63,0.281,,56.06,BAH,-1.43067,0.100394,0.00745029,1.18613 kka2_1:8_D227S,kka2_1:8_227,Kka2,kka2_1:8,P00552,1.18613,NO,227,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.758,-1.053,-0.705,,0.128,H,A,0.75,-0.63,0.281,,56.06,BAH,-1.43067,0.100394,0.00745029,1.18613 kka2_1:8_G43R,kka2_1:8_43,Kka2,kka2_1:8,P00552,1.18615,NO,43,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.587,-2.733,1.146,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.100394,0.0071925,1.18615 kka2_1:8_G43R,kka2_1:8_43,Kka2,kka2_1:8,P00552,1.18615,NO,43,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.587,-2.733,1.146,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.100394,0.0071925,1.18615 beta-lactamase_0_I280S,beta-lactamase_0_280,TEM-1,beta-lactamase_0,P62593,1.18616,NO,280,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.0500837,0.0530888,1.18616 kka2_1:2_P45Q,kka2_1:2_45,Kka2,kka2_1:2,P00552,1.18617,NO,45,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.774,-2.806,1.032,,0.669,,B,0.52,-0.76,4.882,,71.59,BOH,-2.152,0.295029,0.00590481,1.18617 beta-lactamase_0_R92Q,beta-lactamase_0_92,TEM-1,beta-lactamase_0,P62593,1.18623,NO,92,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.718,-3.029,1.311,,0.479,E,B,1.2,1.36,2.331,,65.38,BBH,-1.50367,0.0500837,0.00429626,1.18623 beta-lactamase_0_D129N,beta-lactamase_0_129,TEM-1,beta-lactamase_0,P62593,1.18624,NO,129,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.816,-3.272,2.456,,,,B,0.75,-0.69,2.66,,34.97,PAP,-0.818,0.0500837,0.00109178,1.18624 beta-lactamase_0_E279Q,beta-lactamase_0_279,TEM-1,beta-lactamase_0,P62593,1.18632,NO,279,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.0500837,0.0192826,1.18632 kka2_1:4_H106P,kka2_1:4_106,Kka2,kka2_1:4,P00552,1.18641,NO,106,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-3.13,-2.907,-0.223,,1.065,.,a,0.17,-0.95,16.74,16.74,71.59,PBH,-2.10433,0.168804,0.00730778,1.18641 kka2_1:8_G234S,kka2_1:8_234,Kka2,kka2_1:8,P00552,1.18642,NO,234,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-2.9,-2.468,-0.432,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.100394,0.00984449,1.18642 kka2_1:8_G234S,kka2_1:8_234,Kka2,kka2_1:8,P00552,1.18642,NO,234,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-2.9,-2.468,-0.432,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.100394,0.00984449,1.18642 kka2_1:4_Q252A,kka2_1:4_252,Kka2,kka2_1:4,P00552,1.18644,NO,252,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.63,-2.051,-0.579,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.168804,0.0121001,1.18644 kka2_1:2_V83E,kka2_1:2_83,Kka2,kka2_1:2,P00552,1.18648,NO,83,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-2.567,-2.291,-0.276,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.295029,0.00650486,1.18648 beta-lactamase_0_F149G,beta-lactamase_0_149,TEM-1,beta-lactamase_0,P62593,1.18651,NO,149,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.299,-3.587,2.288,,0.195,H,A,0.58,0.11,3.518,,63.99,HHH,-1.46067,0.0500837,0.00418462,1.18651 kka2_1:2_A176C,kka2_1:2_176,Kka2,kka2_1:2,P00552,1.18657,NO,176,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.621,-4.973,3.352,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.295029,0.0083587,1.18657 kka2_1:8_D156N,kka2_1:8_156,Kka2,kka2_1:8,P00552,1.18657,NO,156,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.696,-3.632,1.936,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.100394,0.00926998,1.18657 kka2_1:8_D156N,kka2_1:8_156,Kka2,kka2_1:8,P00552,1.18657,NO,156,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.696,-3.632,1.936,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.100394,0.00926998,1.18657 beta-lactamase_0_I285T,beta-lactamase_0_285,TEM-1,beta-lactamase_0,P62593,1.18662,NO,285,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.0500837,0.101555,1.18662 kka2_1:8_W24V,kka2_1:8_24,Kka2,kka2_1:8,P00552,1.18665,NO,24,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-1.779,-2.484,0.705,,0.477,E,B,1.51,-0.21,2.503,,56.06,AHH,-2.24467,0.100394,0.00631564,1.18665 kka2_1:8_W24V,kka2_1:8_24,Kka2,kka2_1:8,P00552,1.18665,NO,24,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-1.779,-2.484,0.705,,0.477,E,B,1.51,-0.21,2.503,,56.06,AHH,-2.24467,0.100394,0.00631564,1.18665 kka2_1:8_A172G,kka2_1:8_172,Kka2,kka2_1:8,P00552,1.18668,NO,172,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.757,-2.418,0.661,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.100394,0.0079265,1.18668 kka2_1:8_A172G,kka2_1:8_172,Kka2,kka2_1:8,P00552,1.18668,NO,172,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.757,-2.418,0.661,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.100394,0.0079265,1.18668 kka2_1:4_V75F,kka2_1:4_75,Kka2,kka2_1:4,P00552,1.1867,NO,75,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-2.06,-2.827,0.767,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.168804,0.00693733,1.1867 kka2_1:4_I29V,kka2_1:4_29,Kka2,kka2_1:4,P00552,1.18672,NO,29,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.692,-2.359,0.667,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.168804,0.00619521,1.18672 kka2_1:8_S11L,kka2_1:8_11,Kka2,kka2_1:8,P00552,1.18691,NO,11,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.322,-1.799,-0.523,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.100394,0.00381691,1.18691 kka2_1:8_S11L,kka2_1:8_11,Kka2,kka2_1:8,P00552,1.18691,NO,11,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.322,-1.799,-0.523,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.100394,0.00381691,1.18691 kka2_1:8_G74Q,kka2_1:8_74,Kka2,kka2_1:8,P00552,1.18692,NO,74,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.18,-3.052,1.872,,0.621,T,l,0.29,0.2,2.014,,64.39,POH,-1.91667,0.100394,0.00587035,1.18692 kka2_1:8_G74Q,kka2_1:8_74,Kka2,kka2_1:8,P00552,1.18692,NO,74,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.18,-3.052,1.872,,0.621,T,l,0.29,0.2,2.014,,64.39,POH,-1.91667,0.100394,0.00587035,1.18692 beta-lactamase_0_D113H,beta-lactamase_0_113,TEM-1,beta-lactamase_0,P62593,1.18693,NO,113,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.829,-4.704,2.875,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.0500837,0.00474112,1.18693 beta-lactamase_0_D155K,beta-lactamase_0_155,TEM-1,beta-lactamase_0,P62593,1.18701,NO,155,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.889,-3.426,2.537,,0.049,,B,0.75,-0.9,16.833,16.833,64.69,OAB,-1.62267,0.0500837,0.00135315,1.18701 beta-lactamase_0_D99Y,beta-lactamase_0_99,TEM-1,beta-lactamase_0,P62593,1.18703,NO,99,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.191,-4.234,3.043,,0.402,G,A,0.75,0.36,0.374,,64.69,PAH,-1.794,0.0500837,0.00305446,1.18703 kka2_1:8_R173K,kka2_1:8_173,Kka2,kka2_1:8,P00552,1.18704,NO,173,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.407,-2.916,0.509,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.100394,0.00784999,1.18704 kka2_1:8_R173K,kka2_1:8_173,Kka2,kka2_1:8,P00552,1.18704,NO,173,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.407,-2.916,0.509,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.100394,0.00784999,1.18704 beta-lactamase_0_I140H,beta-lactamase_0_140,TEM-1,beta-lactamase_0,P62593,1.18709,NO,140,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.733,-4.991,3.258,,0.128,H,A,0.48,0.41,4.714,,73.08,PHO,-1.48733,0.0500837,0.00597777,1.18709 kka2_1:8_T73K,kka2_1:8_73,Kka2,kka2_1:8,P00552,1.18713,NO,73,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.51,-2.995,0.485,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.100394,0.00628605,1.18713 kka2_1:8_T73K,kka2_1:8_73,Kka2,kka2_1:8,P00552,1.18713,NO,73,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.51,-2.995,0.485,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.100394,0.00628605,1.18713 kka2_1:4_I254L,kka2_1:4_254,Kka2,kka2_1:4,P00552,1.18722,NO,254,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.933,-1.561,-0.372,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.168804,0.0132375,1.18722 kka2_1:4_Q26K,kka2_1:4_26,Kka2,kka2_1:4,P00552,1.18723,NO,26,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.18,-2.687,0.507,,0.448,E,B,0.4,0.44,5.022,,92.05,HPP,-2.11167,0.168804,0.00708962,1.18723 beta-lactamase_0_S283C,beta-lactamase_0_283,TEM-1,beta-lactamase_0,P62593,1.18724,NO,283,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.0500837,0.0429138,1.18724 kka2_1:2_H106R,kka2_1:2_106,Kka2,kka2_1:2,P00552,1.18725,NO,106,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-3.13,-2.944,-0.186,,1.065,.,a,0.17,-0.95,2.53,,71.59,PBH,-2.10433,0.295029,0.00730778,1.18725 beta-lactamase_0_V106F,beta-lactamase_0_106,TEM-1,beta-lactamase_0,P62593,1.18745,NO,106,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.218,-2.585,1.367,,0.258,T,A,0.44,0.24,0.952,,72.73,OHP,-1.04933,0.0500837,0.00304168,1.18745 kka2_1:8_I29R,kka2_1:8_29,Kka2,kka2_1:8,P00552,1.18745,NO,29,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.692,-4.083,2.391,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.100394,0.00619521,1.18745 kka2_1:8_I29R,kka2_1:8_29,Kka2,kka2_1:8,P00552,1.18745,NO,29,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.692,-4.083,2.391,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.100394,0.00619521,1.18745 kka2_1:4_A172E,kka2_1:4_172,Kka2,kka2_1:4,P00552,1.18747,NO,172,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.757,-2.527,0.77,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.168804,0.0079265,1.18747 kka2_1:8_S251H,kka2_1:8_251,Kka2,kka2_1:8,P00552,1.18755,NO,251,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.636,-3.222,0.586,,0.712,H,A,0.27,-0.25,,,71.59,APP,-2.09367,0.100394,0.0138916,1.18755 kka2_1:8_S251H,kka2_1:8_251,Kka2,kka2_1:8,P00552,1.18755,NO,251,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.636,-3.222,0.586,,0.712,H,A,0.27,-0.25,,,71.59,APP,-2.09367,0.100394,0.0138916,1.18755 kka2_1:4_A129L,kka2_1:4_129,Kka2,kka2_1:4,P00552,1.18758,NO,129,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.656,-3.565,1.909,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.168804,0.00726862,1.18758 kka2_1:2_A247E,kka2_1:2_247,Kka2,kka2_1:2,P00552,1.1876,NO,247,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.459,-2.615,0.156,,1.01,S,A,0.46,0.65,0.828,,92.05,HHH,-2.197,0.295029,0.0102428,1.1876 kka2_1:2_H139R,kka2_1:2_139,Kka2,kka2_1:2,P00552,1.18761,NO,139,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-2.809,-2.657,-0.152,,0.471,H,A,0.87,0.68,13.912,13.912,63.64,BBB,-2.22,0.295029,0.00734779,1.18761 kka2_1:8_Q252Y,kka2_1:8_252,Kka2,kka2_1:8,P00552,1.18761,NO,252,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.63,-4.393,1.763,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.100394,0.0121001,1.18761 kka2_1:8_Q252Y,kka2_1:8_252,Kka2,kka2_1:8,P00552,1.18761,NO,252,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.63,-4.393,1.763,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.100394,0.0121001,1.18761 kka2_1:8_A64M,kka2_1:8_64,Kka2,kka2_1:8,P00552,1.18764,NO,64,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.496,-4.439,2.943,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.100394,0.00705578,1.18764 kka2_1:8_A64M,kka2_1:8_64,Kka2,kka2_1:8,P00552,1.18764,NO,64,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.496,-4.439,2.943,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.100394,0.00705578,1.18764 kka2_1:1_A25V,kka2_1:1_25,Kka2,kka2_1:1,P00552,1.18769,NO,25,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.496,-2.849,0.353,,0.427,E,B,0.46,-0.47,6.872,6.872,65.53,HHP,-2.15167,0.520039,0.00595636,1.18769 kka2_1:4_I29K,kka2_1:4_29,Kka2,kka2_1:4,P00552,1.18772,NO,29,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.692,-3.779,2.087,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.168804,0.00619521,1.18772 kka2_1:4_A176N,kka2_1:4_176,Kka2,kka2_1:4,P00552,1.18777,NO,176,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.621,-3.03,1.409,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.168804,0.0083587,1.18777 kka2_1:8_P12C,kka2_1:8_12,Kka2,kka2_1:8,P00552,1.18782,NO,12,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.853,-4.98,4.127,,,.,B,0.52,1.25,2.41,,48.11,POH,-1.80767,0.100394,0.00500011,1.18782 kka2_1:8_P12C,kka2_1:8_12,Kka2,kka2_1:8,P00552,1.18782,NO,12,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.853,-4.98,4.127,,,.,B,0.52,1.25,2.41,,48.11,POH,-1.80767,0.100394,0.00500011,1.18782 beta-lactamase_0_D129F,beta-lactamase_0_129,TEM-1,beta-lactamase_0,P62593,1.18783,NO,129,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.816,-4.318,3.502,,,,B,0.75,-0.69,2.66,,34.97,PAP,-0.818,0.0500837,0.00109178,1.18783 kka2_1:4_Q42H,kka2_1:4_42,Kka2,kka2_1:4,P00552,1.18784,NO,42,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.907,-3.3,0.393,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.168804,0.00679212,1.18784 kka2_1:2_G21E,kka2_1:2_21,Kka2,kka2_1:2,P00552,1.18787,NO,21,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.368,-3.414,2.046,,0.586,T,l,0.29,-0.75,2.026,,71.59,HOH,-2.10167,0.295029,0.00709648,1.18787 kka2_1:4_E230V,kka2_1:4_230,Kka2,kka2_1:4,P00552,1.18791,NO,230,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.672,-3.108,0.436,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.168804,0.00920051,1.18791 kka2_1:4_R202E,kka2_1:4_202,Kka2,kka2_1:4,P00552,1.18793,NO,202,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.761,-2.596,0.835,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.168804,0.00696498,1.18793 kka2_1:4_R173F,kka2_1:4_173,Kka2,kka2_1:4,P00552,1.18808,NO,173,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.407,-4.245,1.838,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.168804,0.00784999,1.18808 kka2_1:8_I254F,kka2_1:8_254,Kka2,kka2_1:8,P00552,1.1881,NO,254,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.933,-3.851,1.918,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.100394,0.0132375,1.1881 kka2_1:8_I254F,kka2_1:8_254,Kka2,kka2_1:8,P00552,1.1881,NO,254,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.933,-3.851,1.918,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.100394,0.0132375,1.1881 beta-lactamase_0_A148V,beta-lactamase_0_148,TEM-1,beta-lactamase_0,P62593,1.18812,NO,148,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.757,-3.631,1.874,,0.379,H,A,0.46,-0.55,19.42,19.42,72.73,PHH,-1.40167,0.0500837,0.00547053,1.18812 kka2_1:4_D82G,kka2_1:4_82,Kka2,kka2_1:4,P00552,1.18815,NO,82,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.946,-2.495,0.549,,0.341,E,b,0.75,0.52,11.923,11.923,63.64,HAH,-1.98,0.168804,0.00637516,1.18815 kka2_1:2_G151Q,kka2_1:2_151,Kka2,kka2_1:2,P00552,1.18821,NO,151,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.873,-4.048,3.175,,0.678,T,l,0.29,1.36,1.357,,49.62,HOH,-1.11433,0.295029,0.00339918,1.18821 kka2_1:4_G181D,kka2_1:4_181,Kka2,kka2_1:4,P00552,1.18822,NO,181,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-2.698,-2.653,-0.045,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.168804,0.00728319,1.18822 kka2_1:8_E17K,kka2_1:8_17,Kka2,kka2_1:8,P00552,1.18825,NO,17,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.154,-2.831,0.677,,0.957,T,A,1.04,0.22,31.483,31.483,63.64,HAB,-2.432,0.100394,0.00688738,1.18825 kka2_1:8_E17K,kka2_1:8_17,Kka2,kka2_1:8,P00552,1.18825,NO,17,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.154,-2.831,0.677,,0.957,T,A,1.04,0.22,31.483,31.483,63.64,HAB,-2.432,0.100394,0.00688738,1.18825 kka2_1:8_N58T,kka2_1:8_58,Kka2,kka2_1:8,P00552,1.18834,NO,58,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-2.641,-2.933,0.292,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.100394,0.00793425,1.18834 kka2_1:8_N58T,kka2_1:8_58,Kka2,kka2_1:8,P00552,1.18834,NO,58,N,T,NT,Polar,Polar,5.47157,5.6,0.128425,65,132,119,-13,114.1,116.1,2,-2.641,-2.933,0.292,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.100394,0.00793425,1.18834 WW_domain_D194Q,WW_domain_194,Yap65,WW_domain,P46937,1.18847,NO,194,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.536,-3.561,2.025,5.95614,,,,,,1.948,,74.4,HAP,-1.78933,0.153962,0.00483742,1.18847 kka2_1:8_F133W,kka2_1:8_133,Kka2,kka2_1:8,P00552,1.18867,NO,133,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-0.871,-4.449,3.578,,0.178,,B,1.62,0.43,1.816,,42.42,OHA,-0.871667,0.100394,0.00182168,1.18867 kka2_1:8_F133W,kka2_1:8_133,Kka2,kka2_1:8,P00552,1.18867,NO,133,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-0.871,-4.449,3.578,,0.178,,B,1.62,0.43,1.816,,42.42,OHA,-0.871667,0.100394,0.00182168,1.18867 kka2_1:4_Q26A,kka2_1:4_26,Kka2,kka2_1:4,P00552,1.18868,NO,26,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.18,-2.361,0.181,,0.448,E,B,0.4,0.44,5.022,,92.05,HPP,-2.11167,0.168804,0.00708962,1.18868 kka2_1:4_M197L,kka2_1:4_197,Kka2,kka2_1:4,P00552,1.18869,NO,197,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.707,-1.777,0.07,,0.121,E,B,0.55,-1.19,0.415,,65.53,HHH,-1.847,0.168804,0.00921295,1.18869 beta-lactamase_0_F58A,beta-lactamase_0_58,TEM-1,beta-lactamase_0,P62593,1.18886,NO,58,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-2.914,-3.389,0.475,,0.266,E,B,0.58,-0.07,24.637,24.637,77.62,PHB,-2.059,0.0500837,0.00523369,1.18886 beta-lactamase_0_R118T,beta-lactamase_0_118,TEM-1,beta-lactamase_0,P62593,1.18887,NO,118,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.413,-2.845,0.432,,0.457,H,A,1.2,1.39,3.961,,77.62,HBA,-1.785,0.0500837,0.00538794,1.18887 kka2_1:8_V75Y,kka2_1:8_75,Kka2,kka2_1:8,P00552,1.18892,NO,75,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-2.06,-4.054,1.994,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.100394,0.00693733,1.18892 kka2_1:8_V75Y,kka2_1:8_75,Kka2,kka2_1:8,P00552,1.18892,NO,75,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-2.06,-4.054,1.994,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.100394,0.00693733,1.18892 kka2_1:8_G10E,kka2_1:8_10,Kka2,kka2_1:8,P00552,1.18909,NO,10,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.921,-2.456,0.535,,,,,,,1.862,,71.59,HOP,-2.10733,0.100394,0.00289233,1.18909 kka2_1:8_G10E,kka2_1:8_10,Kka2,kka2_1:8,P00552,1.18909,NO,10,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.921,-2.456,0.535,,,,,,,1.862,,71.59,HOP,-2.10733,0.100394,0.00289233,1.18909 kka2_1:1_Q42E,kka2_1:1_42,Kka2,kka2_1:1,P00552,1.1891,NO,42,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.907,-2.56,-0.347,,1.044,T,B,0.4,-0.8,2.792,,71.59,HPO,-2.12433,0.520039,0.00679212,1.1891 kka2_1:8_S54C,kka2_1:8_54,Kka2,kka2_1:8,P00552,1.18918,NO,54,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.471,-4.966,2.495,,0.408,S,b,0.77,1.01,13.679,13.679,71.59,HPO,-2.259,0.100394,0.00782867,1.18918 kka2_1:8_S54C,kka2_1:8_54,Kka2,kka2_1:8,P00552,1.18918,NO,54,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.471,-4.966,2.495,,0.408,S,b,0.77,1.01,13.679,13.679,71.59,HPO,-2.259,0.100394,0.00782867,1.18918 kka2_1:2_A172C,kka2_1:2_172,Kka2,kka2_1:2,P00552,1.18922,NO,172,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.757,-5.069,3.312,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.295029,0.0079265,1.18922 kka2_1:2_D33G,kka2_1:2_33,Kka2,kka2_1:2,P00552,1.18929,NO,33,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.186,-2.077,-0.109,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.295029,0.00633568,1.18929 kka2_1:8_D134Q,kka2_1:8_134,Kka2,kka2_1:8,P00552,1.18932,NO,134,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.969,-3.77,2.801,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.100394,0.00270812,1.18932 kka2_1:8_D134Q,kka2_1:8_134,Kka2,kka2_1:8,P00552,1.18932,NO,134,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.969,-3.77,2.801,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.100394,0.00270812,1.18932 kka2_1:4_E169H,kka2_1:4_169,Kka2,kka2_1:4,P00552,1.1894,NO,169,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.996,-4.724,2.728,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.168804,0.00730086,1.1894 kka2_1:8_A78P,kka2_1:8_78,Kka2,kka2_1:8,P00552,1.1894,NO,78,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.744,-0.97,-0.774,,0.078,,B,1.04,-0.53,1.251,,56.06,OHH,-1.863,0.100394,0.00457299,1.1894 kka2_1:8_A78P,kka2_1:8_78,Kka2,kka2_1:8,P00552,1.1894,NO,78,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.744,-0.97,-0.774,,0.078,,B,1.04,-0.53,1.251,,56.06,OHH,-1.863,0.100394,0.00457299,1.1894 kka2_1:4_A247S,kka2_1:4_247,Kka2,kka2_1:4,P00552,1.18941,NO,247,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.459,-2.453,-0.006,,1.01,S,A,0.46,0.65,,,92.05,HHH,-2.197,0.168804,0.0102428,1.18941 kka2_1:8_D154Q,kka2_1:8_154,Kka2,kka2_1:8,P00552,1.18941,NO,154,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.876,-3.709,2.833,,0.457,,b,0.29,1.48,0.844,,52.65,HAP,-1.52467,0.100394,0.00292633,1.18941 kka2_1:8_D154Q,kka2_1:8_154,Kka2,kka2_1:8,P00552,1.18941,NO,154,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.876,-3.709,2.833,,0.457,,b,0.29,1.48,0.844,,52.65,HAP,-1.52467,0.100394,0.00292633,1.18941 kka2_1:8_A176P,kka2_1:8_176,Kka2,kka2_1:8,P00552,1.18943,NO,176,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.621,-3.934,2.313,,0.806,H,A,0.46,-0.03,18.904,18.904,65.53,BHB,-2.26667,0.100394,0.0083587,1.18943 kka2_1:8_A176P,kka2_1:8_176,Kka2,kka2_1:8,P00552,1.18943,NO,176,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.621,-3.934,2.313,,0.806,H,A,0.46,-0.03,18.904,18.904,65.53,BHB,-2.26667,0.100394,0.0083587,1.18943 beta-lactamase_0_L160M,beta-lactamase_0_160,TEM-1,beta-lactamase_0,P62593,1.18963,NO,160,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.977,-3.902,2.925,,0.022,,B,0.55,-0.6,0.68,,44.41,BHA,-0.936,0.0500837,0.00193775,1.18963 kka2_1:2_S11N,kka2_1:2_11,Kka2,kka2_1:2,P00552,1.18965,NO,11,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.322,-3.885,1.563,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.295029,0.00381691,1.18965 kka2_1:8_L165A,kka2_1:8_165,Kka2,kka2_1:8,P00552,1.18968,NO,165,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-2.453,-2.69,0.237,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.100394,0.00801161,1.18968 kka2_1:8_L165A,kka2_1:8_165,Kka2,kka2_1:8,P00552,1.18968,NO,165,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-2.453,-2.69,0.237,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.100394,0.00801161,1.18968 WW_domain_D170V,WW_domain_170,Yap65,WW_domain,P46937,1.18968,NO,170,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.213,-3.524,2.311,,,,,,,0.399,,15.87,OAH,-1.38,0.153962,0.00123319,1.18968 kka2_1:4_A168H,kka2_1:4_168,Kka2,kka2_1:4,P00552,1.18969,NO,168,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.989,-3.256,1.267,,0.67,H,A,0.46,0.15,,,64.39,OHA,-2.12933,0.168804,0.00806773,1.18969 kka2_1:4_D23L,kka2_1:4_23,Kka2,kka2_1:4,P00552,1.18974,NO,23,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.459,-2.907,0.448,,0.695,E,B,0.75,-0.65,2.416,,65.53,HAH,-1.94033,0.168804,0.007195,1.18974 kka2_1:2_E160D,kka2_1:2_160,Kka2,kka2_1:2,P00552,1.18976,NO,160,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.683,-1.462,-0.221,,0.989,G,A,1.04,2.28,3.948,,71.59,AAA,-1.36133,0.295029,0.00935762,1.18976 kka2_1:2_G43T,kka2_1:2_43,Kka2,kka2_1:2,P00552,1.18982,NO,43,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.587,-2.998,1.411,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.295029,0.0071925,1.18982 kka2_1:8_D5V,kka2_1:8_5,Kka2,kka2_1:8,P00552,1.18983,NO,5,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.306,-3.484,2.178,,,,,,,1.147,,71.59,PAO,-1.784,0.100394,0.00222864,1.18983 kka2_1:8_D5V,kka2_1:8_5,Kka2,kka2_1:8,P00552,1.18983,NO,5,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.306,-3.484,2.178,,,,,,,1.147,,71.59,PAO,-1.784,0.100394,0.00222864,1.18983 beta-lactamase_0_S283H,beta-lactamase_0_283,TEM-1,beta-lactamase_0,P62593,1.19,NO,283,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.0500837,0.0429138,1.19 kka2_1:4_A41C,kka2_1:4_41,Kka2,kka2_1:4,P00552,1.19,NO,41,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.879,-3.65,1.771,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.168804,0.00543332,1.19 kka2_1:4_E161M,kka2_1:4_161,Kka2,kka2_1:4,P00552,1.19006,NO,161,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.581,-4.788,3.207,,0.829,G,A,1.52,2.24,1.612,,92.05,AAB,-1.861,0.168804,0.00760103,1.19006 kka2_1:2_S204A,kka2_1:2_204,Kka2,kka2_1:2,P00552,1.19018,NO,204,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.353,-1.861,0.508,,0.144,E,A,0.27,-1.2,2.442,,65.53,HPO,-0.953333,0.295029,0.00881794,1.19018 kka2_1:4_A41D,kka2_1:4_41,Kka2,kka2_1:4,P00552,1.19019,NO,41,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.879,-3.164,1.285,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.168804,0.00543332,1.19019 kka2_1:4_R18I,kka2_1:4_18,Kka2,kka2_1:4,P00552,1.1902,NO,18,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.055,-3.256,1.201,,0.474,T,A,1.2,0.54,8.405,8.405,71.59,ABH,-1.821,0.168804,0.00724065,1.1902 beta-lactamase_0_A211Y,beta-lactamase_0_211,TEM-1,beta-lactamase_0,P62593,1.19021,NO,211,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.896,-4.344,2.448,,0.369,T,A,0.46,-0.69,8.527,8.527,77.62,AHA,-1.94633,0.0500837,0.00648183,1.19021 kka2_1:8_A14V,kka2_1:8_14,Kka2,kka2_1:8,P00552,1.19022,NO,14,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.837,-2.963,1.126,,0.728,G,A,0.46,0.7,,,71.59,HHH,-1.82567,0.100394,0.00706614,1.19022 kka2_1:8_A14V,kka2_1:8_14,Kka2,kka2_1:8,P00552,1.19022,NO,14,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.837,-2.963,1.126,,0.728,G,A,0.46,0.7,,,71.59,HHH,-1.82567,0.100394,0.00706614,1.19022 kka2_1:8_A13V,kka2_1:8_13,Kka2,kka2_1:8,P00552,1.19023,NO,13,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.248,-2.845,0.597,,0.689,G,A,1.04,0.99,14.966,14.966,92.05,OHH,-1.646,0.100394,0.00784241,1.19023 kka2_1:8_A13V,kka2_1:8_13,Kka2,kka2_1:8,P00552,1.19023,NO,13,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.248,-2.845,0.597,,0.689,G,A,1.04,0.99,14.966,14.966,92.05,OHH,-1.646,0.100394,0.00784241,1.19023 kka2_1:8_Q155G,kka2_1:8_155,Kka2,kka2_1:8,P00552,1.19024,NO,155,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.606,-2.641,0.035,,0.525,T,A,0.64,1.49,,,63.64,APA,-1.726,0.100394,0.00641853,1.19024 kka2_1:8_Q155G,kka2_1:8_155,Kka2,kka2_1:8,P00552,1.19024,NO,155,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.606,-2.641,0.035,,0.525,T,A,0.64,1.49,,,63.64,APA,-1.726,0.100394,0.00641853,1.19024 beta-lactamase_0_G240Y,beta-lactamase_0_240,TEM-1,beta-lactamase_0,P62593,1.19038,NO,240,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.537,,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.0500837,0.00591201,1.19038 kka2_1:4_D5G,kka2_1:4_5,Kka2,kka2_1:4,P00552,1.19046,NO,5,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.306,-3.014,1.708,,,,,,,,,71.59,PAO,-1.784,0.168804,0.00222864,1.19046 beta-lactamase_0_T27Y,beta-lactamase_0_27,TEM-1,beta-lactamase_0,P62593,1.19053,NO,27,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.905,-4.144,2.239,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.0500837,0.00306559,1.19053 kka2_1:2_E3W,kka2_1:2_3,Kka2,kka2_1:2,P00552,1.19063,NO,3,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.199,-4.936,2.737,,,,,,,7.22,,92.05,HAP,-2.11567,0.295029,0.00267607,1.19063 kka2_1:8_A13T,kka2_1:8_13,Kka2,kka2_1:8,P00552,1.19067,NO,13,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.248,-2.994,0.746,,0.689,G,A,1.04,0.99,14.966,14.966,92.05,OHH,-1.646,0.100394,0.00784241,1.19067 kka2_1:8_A13T,kka2_1:8_13,Kka2,kka2_1:8,P00552,1.19067,NO,13,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.248,-2.994,0.746,,0.689,G,A,1.04,0.99,14.966,14.966,92.05,OHH,-1.646,0.100394,0.00784241,1.19067 kka2_1:8_Q100T,kka2_1:8_100,Kka2,kka2_1:8,P00552,1.19072,NO,100,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.77,-2.757,-0.013,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.100394,0.0066405,1.19072 kka2_1:8_Q100T,kka2_1:8_100,Kka2,kka2_1:8,P00552,1.19072,NO,100,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.77,-2.757,-0.013,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.100394,0.0066405,1.19072 kka2_1:8_L19F,kka2_1:8_19,Kka2,kka2_1:8,P00552,1.19088,NO,19,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.254,-2.137,0.883,,0.08,T,A,1.59,-0.26,2.044,,65.53,BHH,-2.221,0.100394,0.00620703,1.19088 kka2_1:8_L19F,kka2_1:8_19,Kka2,kka2_1:8,P00552,1.19088,NO,19,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.254,-2.137,0.883,,0.08,T,A,1.59,-0.26,2.044,,65.53,BHH,-2.221,0.100394,0.00620703,1.19088 kka2_1:4_A87Q,kka2_1:4_87,Kka2,kka2_1:4,P00552,1.19089,NO,87,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.917,-3.008,1.091,,1.039,S,L,0.46,1.57,22.675,22.675,65.53,AHO,-1.822,0.168804,0.00791281,1.19089 beta-lactamase_0_F228H,beta-lactamase_0_228,TEM-1,beta-lactamase_0,P62593,1.19096,NO,228,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-2.342,-3.331,0.989,,0.154,E,B,0.58,-0.42,15.504,15.504,63.29,HHH,-1.53033,0.0500837,0.0046669,1.19096 kka2_1:8_G181R,kka2_1:8_181,Kka2,kka2_1:8,P00552,1.19101,NO,181,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-2.698,-2.623,-0.075,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.100394,0.00728319,1.19101 kka2_1:8_G181R,kka2_1:8_181,Kka2,kka2_1:8,P00552,1.19101,NO,181,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-2.698,-2.623,-0.075,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.100394,0.00728319,1.19101 kka2_1:8_A172M,kka2_1:8_172,Kka2,kka2_1:8,P00552,1.19106,NO,172,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.757,-4.761,3.004,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.100394,0.0079265,1.19106 kka2_1:8_A172M,kka2_1:8_172,Kka2,kka2_1:8,P00552,1.19106,NO,172,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.757,-4.761,3.004,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.100394,0.0079265,1.19106 kka2_1:8_F264Y,kka2_1:8_264,Kka2,kka2_1:8,P00552,1.19117,NO,264,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.02,-2.016,0.996,,0.296,,?,1.62,0.02,1.553,,71.59,HHO,-0.9655,0.100394,,1.19117 kka2_1:8_F264Y,kka2_1:8_264,Kka2,kka2_1:8,P00552,1.19117,NO,264,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.02,-2.016,0.996,,0.296,,?,1.62,0.02,1.553,,71.59,HHO,-0.9655,0.100394,,1.19117 kka2_1:8_P194D,kka2_1:8_194,Kka2,kka2_1:8,P00552,1.19125,NO,194,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.846,-2.601,1.755,,0.308,G,A,0.52,-1.19,4.861,,53.03,HOP,-0.888333,0.100394,0.00314194,1.19125 kka2_1:8_P194D,kka2_1:8_194,Kka2,kka2_1:8,P00552,1.19125,NO,194,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-0.846,-2.601,1.755,,0.308,G,A,0.52,-1.19,4.861,,53.03,HOP,-0.888333,0.100394,0.00314194,1.19125 beta-lactamase_0_E61M,beta-lactamase_0_61,TEM-1,beta-lactamase_0,P62593,1.19129,NO,61,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.115,-4.881,2.766,,0.775,T,a,1.04,1.29,34.763,34.763,77.62,OAA,-1.92567,0.0500837,0.00440955,1.19129 kka2_1:8_E3N,kka2_1:8_3,Kka2,kka2_1:8,P00552,1.19131,NO,3,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.199,-3.328,1.129,,,,,,,7.22,,92.05,HAP,-2.11567,0.100394,0.00267607,1.19131 kka2_1:8_E3N,kka2_1:8_3,Kka2,kka2_1:8,P00552,1.19131,NO,3,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.199,-3.328,1.129,,,,,,,7.22,,92.05,HAP,-2.11567,0.100394,0.00267607,1.19131 kka2_1:2_Q42N,kka2_1:2_42,Kka2,kka2_1:2,P00552,1.19137,NO,42,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.907,-2.98,0.073,,1.044,T,B,0.64,-0.8,2.792,,71.59,HPO,-2.12433,0.295029,0.00679212,1.19137 kka2_1:8_S40A,kka2_1:8_40,Kka2,kka2_1:8,P00552,1.19141,NO,40,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.645,-2.559,-0.086,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.100394,0.00693477,1.19141 kka2_1:8_S40A,kka2_1:8_40,Kka2,kka2_1:8,P00552,1.19141,NO,40,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.645,-2.559,-0.086,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.100394,0.00693477,1.19141 beta-lactamase_0_Q88T,beta-lactamase_0_88,TEM-1,beta-lactamase_0,P62593,1.19144,NO,88,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.086,-2.693,0.607,,0.807,,B,0.64,2.03,0.4,,77.62,APH,-1.53433,0.0500837,0.00504167,1.19144 kka2_1:8_L7F,kka2_1:8_7,Kka2,kka2_1:8,P00552,1.19149,NO,7,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.926,-3.787,1.861,,,,,,,,,71.59,OHB,-2.12333,0.100394,0.00269456,1.19149 kka2_1:8_L7F,kka2_1:8_7,Kka2,kka2_1:8,P00552,1.19149,NO,7,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.926,-3.787,1.861,,,,,,,,,71.59,OHB,-2.12333,0.100394,0.00269456,1.19149 kka2_1:8_G10Q,kka2_1:8_10,Kka2,kka2_1:8,P00552,1.19161,NO,10,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.921,-2.7,0.779,,,,,,,1.862,,71.59,HOP,-2.10733,0.100394,0.00289233,1.19161 kka2_1:8_G10Q,kka2_1:8_10,Kka2,kka2_1:8,P00552,1.19161,NO,10,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.921,-2.7,0.779,,,,,,,1.862,,71.59,HOP,-2.10733,0.100394,0.00289233,1.19161 beta-lactamase_0_M180T,beta-lactamase_0_180,TEM-1,beta-lactamase_0,P62593,1.19164,NO,180,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-2.795,-1.278,-1.517,,0.242,,B,0.55,-0.94,2.892,,77.62,PHO,-1.56433,0.0500837,0.00552048,1.19164 kka2_1:4_G164Q,kka2_1:4_164,Kka2,kka2_1:4,P00552,1.19164,NO,164,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.869,-4.074,3.205,,0.862,T,l,0.75,1.45,1.539,,64.39,POH,-1.828,0.168804,0.00442091,1.19164 kka2_1:8_T51H,kka2_1:8_51,Kka2,kka2_1:8,P00552,1.19164,NO,51,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.199,-2.994,0.795,,0.05,E,B,0.82,-0.05,5.399,,63.64,BPA,-1.76767,0.100394,0.00628861,1.19164 kka2_1:8_T51H,kka2_1:8_51,Kka2,kka2_1:8,P00552,1.19164,NO,51,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.199,-2.994,0.795,,0.05,E,B,0.82,-0.05,5.399,,63.64,BPA,-1.76767,0.100394,0.00628861,1.19164 beta-lactamase_0_E166Y,beta-lactamase_0_166,TEM-1,beta-lactamase_0,P62593,1.19166,NO,166,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.756,-4.36,2.604,,0.508,G,A,1.04,1.05,17.227,17.227,73.08,OAH,-1.42233,0.0500837,0.00512989,1.19166 beta-lactamase_0_L196R,beta-lactamase_0_196,TEM-1,beta-lactamase_0,P62593,1.19177,NO,196,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-2.478,-2.59,0.112,,0.518,S,A,0.55,1.35,6.513,6.513,77.62,AHH,-1.839,0.0500837,0.00512144,1.19177 beta-lactamase_0_K30N,beta-lactamase_0_30,TEM-1,beta-lactamase_0,P62593,1.19181,NO,30,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-2.307,-2.865,0.558,,0.142,H,A,2.34,-0.65,1.491,,93.01,HBH,-2.32833,0.0500837,0.00448593,1.19181 kka2_1:4_Q26P,kka2_1:4_26,Kka2,kka2_1:4,P00552,1.19209,NO,26,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.18,-2.701,0.521,,0.448,E,B,0.4,0.44,5.022,,92.05,HPP,-2.11167,0.168804,0.00708962,1.19209 kka2_1:2_L81Q,kka2_1:2_81,Kka2,kka2_1:2,P00552,1.19214,NO,81,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.427,-3.189,1.762,,0.46,E,A,1.59,-0.14,1.895,,63.64,HHA,-1.50567,0.295029,0.00805839,1.19214 kka2_1:4_G95R,kka2_1:4_95,Kka2,kka2_1:4,P00552,1.19215,NO,95,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-2.403,-3.111,0.708,,0.126,E,B,0.29,-0.74,0.359,,71.59,HOA,-2.198,0.168804,0.00743616,1.19215 kka2_1:8_L81W,kka2_1:8_81,Kka2,kka2_1:8,P00552,1.19215,NO,81,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.427,-5.367,3.94,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.100394,0.00805839,1.19215 kka2_1:8_L81W,kka2_1:8_81,Kka2,kka2_1:8,P00552,1.19215,NO,81,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.427,-5.367,3.94,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.100394,0.00805839,1.19215 beta-lactamase_0_E108C,beta-lactamase_0_108,TEM-1,beta-lactamase_0,P62593,1.19218,NO,108,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.46,-5.208,3.748,,0.572,G,A,1.04,1.87,8.602,8.602,72.73,PAB,-1.437,0.0500837,0.00413372,1.19218 kka2_1:2_E160R,kka2_1:2_160,Kka2,kka2_1:2,P00552,1.19219,NO,160,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.683,-3.847,2.164,,0.989,G,A,1.04,2.28,3.948,,71.59,AAA,-1.36133,0.295029,0.00935762,1.19219 kka2_1:8_G234A,kka2_1:8_234,Kka2,kka2_1:8,P00552,1.1922,NO,234,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-2.9,-2.255,-0.645,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.100394,0.00984449,1.1922 kka2_1:8_G234A,kka2_1:8_234,Kka2,kka2_1:8,P00552,1.1922,NO,234,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-2.9,-2.255,-0.645,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.100394,0.00984449,1.1922 beta-lactamase_0_E119V,beta-lactamase_0_119,TEM-1,beta-lactamase_0,P62593,1.19234,NO,119,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.412,-3.661,2.249,,0.358,H,A,1.04,0.51,3.396,,63.99,BAH,-1.623,0.0500837,0.00386966,1.19234 kka2_1:1_V242R,kka2_1:1_242,Kka2,kka2_1:1,P00552,1.19236,NO,242,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-2.687,-2.299,-0.388,,0.75,H,A,0.44,-0.37,4.987,,71.59,HHH,-2.16533,0.520039,0.0102575,1.19236 kka2_1:2_E17P,kka2_1:2_17,Kka2,kka2_1:2,P00552,1.1924,NO,17,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.154,-2.799,0.645,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.295029,0.00688738,1.1924 beta-lactamase_0_R242Q,beta-lactamase_0_242,TEM-1,beta-lactamase_0,P62593,1.19242,NO,242,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.319,,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.0500837,0.00452879,1.19242 beta-lactamase_0_A132P,beta-lactamase_0_132,TEM-1,beta-lactamase_0,P62593,1.1925,NO,132,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.9,-3.725,2.825,,,H,A,0.46,-0.93,2.249,,64.69,PHH,-1.138,0.0500837,0.000962524,1.1925 kka2_1:4_V16P,kka2_1:4_16,Kka2,kka2_1:4,P00552,1.19252,NO,16,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-3.087,-4.081,0.994,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.168804,0.00694011,1.19252 kka2_1:8_A172L,kka2_1:8_172,Kka2,kka2_1:8,P00552,1.19252,NO,172,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.757,-2.996,1.239,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.100394,0.0079265,1.19252 kka2_1:8_A172L,kka2_1:8_172,Kka2,kka2_1:8,P00552,1.19252,NO,172,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.757,-2.996,1.239,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.100394,0.0079265,1.19252 kka2_1:8_A108N,kka2_1:8_108,Kka2,kka2_1:8,P00552,1.19255,NO,108,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.061,-3.827,1.766,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.100394,0.00751209,1.19255 kka2_1:8_A108N,kka2_1:8_108,Kka2,kka2_1:8,P00552,1.19255,NO,108,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.061,-3.827,1.766,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.100394,0.00751209,1.19255 beta-lactamase_0_N152D,beta-lactamase_0_152,TEM-1,beta-lactamase_0,P62593,1.19257,NO,152,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-2.757,-3.573,0.816,,0.863,H,A,0.61,0.92,2.151,,77.62,BPH,-2.97,0.0500837,0.00471429,1.19257 kka2_1:4_P249A,kka2_1:4_249,Kka2,kka2_1:4,P00552,1.19257,NO,249,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.867,-2.101,0.234,,0.406,.,B,0.52,-0.01,,,92.05,HOA,-1.66867,0.168804,0.011045,1.19257 kka2_1:1_V16A,kka2_1:1_16,Kka2,kka2_1:1,P00552,1.19258,NO,16,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-3.087,-2.407,-0.68,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.520039,0.00694011,1.19258 kka2_1:8_A191F,kka2_1:8_191,Kka2,kka2_1:8,P00552,1.19258,NO,191,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.831,-4.183,3.352,,,,b,1.04,-0.94,1.306,,50,AHO,-0.868667,0.100394,0.00338807,1.19258 kka2_1:8_A191F,kka2_1:8_191,Kka2,kka2_1:8,P00552,1.19258,NO,191,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.831,-4.183,3.352,,,,b,1.04,-0.94,1.306,,50,AHO,-0.868667,0.100394,0.00338807,1.19258 kka2_1:8_H106E,kka2_1:8_106,Kka2,kka2_1:8,P00552,1.19277,NO,106,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-3.13,-2.347,-0.783,,1.065,,a,0.87,-0.95,15.956,15.956,71.59,PBH,-2.10433,0.100394,0.00730778,1.19277 kka2_1:8_H106E,kka2_1:8_106,Kka2,kka2_1:8,P00552,1.19277,NO,106,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-3.13,-2.347,-0.783,,1.065,,a,0.87,-0.95,15.956,15.956,71.59,PBH,-2.10433,0.100394,0.00730778,1.19277 kka2_1:8_D23G,kka2_1:8_23,Kka2,kka2_1:8,P00552,1.19281,NO,23,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.459,-2.651,0.192,,0.695,E,B,0.75,-0.65,,,65.53,HAH,-1.94033,0.100394,0.007195,1.19281 kka2_1:8_D23G,kka2_1:8_23,Kka2,kka2_1:8,P00552,1.19281,NO,23,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.459,-2.651,0.192,,0.695,E,B,0.75,-0.65,,,65.53,HAH,-1.94033,0.100394,0.007195,1.19281 kka2_1:8_Q252G,kka2_1:8_252,Kka2,kka2_1:8,P00552,1.19283,NO,252,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.63,-2.545,-0.085,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.100394,0.0121001,1.19283 kka2_1:8_Q252G,kka2_1:8_252,Kka2,kka2_1:8,P00552,1.19283,NO,252,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.63,-2.545,-0.085,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.100394,0.0121001,1.19283 kka2_1:4_M178E,kka2_1:4_178,Kka2,kka2_1:4,P00552,1.19287,NO,178,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-3.206,-3.572,0.366,,0.554,.,b,0.55,0.68,9.913,9.913,71.59,BHO,-2.154,0.168804,0.00717253,1.19287 beta-lactamase_0_E87A,beta-lactamase_0_87,TEM-1,beta-lactamase_0,P62593,1.19301,NO,87,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.421,-3.209,1.788,,0.048,,B,1.04,0.92,1.159,,64.69,PAP,-1.969,0.0500837,0.00337888,1.19301 kka2_1:8_A137W,kka2_1:8_137,Kka2,kka2_1:8,P00552,1.19301,NO,137,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.156,-2.974,0.818,,0.029,H,A,1.04,0.34,2.886,,63.26,PHB,-2.559,0.100394,0.00515054,1.19301 kka2_1:8_A137W,kka2_1:8_137,Kka2,kka2_1:8,P00552,1.19301,NO,137,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.156,-2.974,0.818,,0.029,H,A,1.04,0.34,2.886,,63.26,PHB,-2.559,0.100394,0.00515054,1.19301 kka2_1:4_R143K,kka2_1:4_143,Kka2,kka2_1:4,P00552,1.19309,NO,143,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.525,-3.061,0.536,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.168804,0.00662247,1.19309 kka2_1:8_A248D,kka2_1:8_248,Kka2,kka2_1:8,P00552,1.19312,NO,248,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.124,-2.58,0.456,,0.825,S,b,1.04,0.46,11.329,11.329,92.05,HHO,-2.15,0.100394,0.0125484,1.19312 kka2_1:8_A248D,kka2_1:8_248,Kka2,kka2_1:8,P00552,1.19312,NO,248,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.124,-2.58,0.456,,0.825,S,b,1.04,0.46,11.329,11.329,92.05,HHO,-2.15,0.100394,0.0125484,1.19312 beta-lactamase_0_G236A,beta-lactamase_0_236,TEM-1,beta-lactamase_0,P62593,1.19314,NO,236,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-0.784,-2.29,1.506,,0.241,,b,0.29,-0.59,3.506,,64.69,HOO,-1.025,0.0500837,0.00162372,1.19314 kka2_1:4_M120L,kka2_1:4_120,Kka2,kka2_1:4,P00552,1.19325,NO,120,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-3.877,-0.807,-3.07,,,H,A,0.55,-0.42,2.259,,92.05,HHB,-2.16733,0.168804,0.00265808,1.19325 WW_domain_V171G,WW_domain_171,Yap65,WW_domain,P46937,1.19326,NO,171,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.547,-3.381,1.834,,,,,,,3.459,,70.24,AHO,-1.265,0.153962,0.00184125,1.19326 kka2_1:8_A41Q,kka2_1:8_41,Kka2,kka2_1:8,P00552,1.19327,NO,41,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.879,-2.908,1.029,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.100394,0.00543332,1.19327 kka2_1:8_A41Q,kka2_1:8_41,Kka2,kka2_1:8,P00552,1.19327,NO,41,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.879,-2.908,1.029,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.100394,0.00543332,1.19327 beta-lactamase_0_T126I,beta-lactamase_0_126,TEM-1,beta-lactamase_0,P62593,1.19333,NO,126,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.122,-3.78,2.658,,0.05,H,A,0.22,-0.05,0.705,,44.41,HPH,-1.60467,0.0500837,0.00244552,1.19333 kka2_1:2_V75T,kka2_1:2_75,Kka2,kka2_1:2,P00552,1.19333,NO,75,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-2.06,-2.915,0.855,,0.042,.,B,0.44,-0.2,2.815,,71.59,OHO,-1.563,0.295029,0.00693733,1.19333 beta-lactamase_0_P255L,beta-lactamase_0_255,TEM-1,beta-lactamase_0,P62593,1.19337,NO,255,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.0500837,0.00499612,1.19337 kka2_1:4_R173C,kka2_1:4_173,Kka2,kka2_1:4,P00552,1.19358,NO,173,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.407,-5.224,2.817,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.168804,0.00784999,1.19358 kka2_1:8_A215G,kka2_1:8_215,Kka2,kka2_1:8,P00552,1.19363,NO,215,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.968,-3.05,2.082,,0.039,E,B,1.04,-0.59,2.77,,50.38,HHA,-1.00467,0.100394,0.00529129,1.19363 kka2_1:8_A215G,kka2_1:8_215,Kka2,kka2_1:8,P00552,1.19363,NO,215,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-0.968,-3.05,2.082,,0.039,E,B,1.04,-0.59,2.77,,50.38,HHA,-1.00467,0.100394,0.00529129,1.19363 kka2_1:4_G95Q,kka2_1:4_95,Kka2,kka2_1:4,P00552,1.19374,NO,95,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-2.403,-2.902,0.499,,0.126,E,B,0.29,-0.74,0.359,,71.59,HOA,-2.198,0.168804,0.00743616,1.19374 kka2_1:8_K175M,kka2_1:8_175,Kka2,kka2_1:8,P00552,1.19374,NO,175,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-2.897,-3.26,0.363,,0.579,H,A,2.34,0.51,15.316,15.316,71.59,HBH,-1.82333,0.100394,0.00693093,1.19374 kka2_1:8_K175M,kka2_1:8_175,Kka2,kka2_1:8,P00552,1.19374,NO,175,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-2.897,-3.26,0.363,,0.579,H,A,2.34,0.51,15.316,15.316,71.59,HBH,-1.82333,0.100394,0.00693093,1.19374 kka2_1:4_V49C,kka2_1:4_49,Kka2,kka2_1:4,P00552,1.19376,NO,49,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.614,-4.784,3.17,,,E,B,0.44,-0.77,1.233,,64.39,HHB,-1.3,0.168804,0.00615685,1.19376 kka2_1:8_V153C,kka2_1:8_153,Kka2,kka2_1:8,P00552,1.19383,NO,153,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.092,-4.724,3.632,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.100394,0.00501119,1.19383 kka2_1:8_V153C,kka2_1:8_153,Kka2,kka2_1:8,P00552,1.19383,NO,153,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.092,-4.724,3.632,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.100394,0.00501119,1.19383 kka2_1:8_Q100C,kka2_1:8_100,Kka2,kka2_1:8,P00552,1.19392,NO,100,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.77,-3.712,0.942,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.100394,0.0066405,1.19392 kka2_1:8_Q100C,kka2_1:8_100,Kka2,kka2_1:8,P00552,1.19392,NO,100,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.77,-3.712,0.942,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.100394,0.0066405,1.19392 beta-lactamase_0_A182N,beta-lactamase_0_182,TEM-1,beta-lactamase_0,P62593,1.19406,NO,182,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.777,-3.015,1.238,,0.136,H,A,0.46,-0.66,10.765,10.765,93.01,OHH,-1.27367,0.0500837,0.00559099,1.19406 kka2_1:8_A191M,kka2_1:8_191,Kka2,kka2_1:8,P00552,1.19406,NO,191,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.831,-4.572,3.741,,,,b,1.04,-0.94,1.306,,50,AHO,-0.868667,0.100394,0.00338807,1.19406 kka2_1:8_A191M,kka2_1:8_191,Kka2,kka2_1:8,P00552,1.19406,NO,191,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.831,-4.572,3.741,,,,b,1.04,-0.94,1.306,,50,AHO,-0.868667,0.100394,0.00338807,1.19406 beta-lactamase_0_S283Q,beta-lactamase_0_283,TEM-1,beta-lactamase_0,P62593,1.1941,NO,283,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.0500837,0.0429138,1.1941 kka2_1:4_G21Q,kka2_1:4_21,Kka2,kka2_1:4,P00552,1.19416,NO,21,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.368,-2.867,1.499,,0.586,T,l,0.75,-0.75,3.075,,71.59,HOH,-2.10167,0.168804,0.00709648,1.19416 kka2_1:4_M178V,kka2_1:4_178,Kka2,kka2_1:4,P00552,1.1942,NO,178,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-3.206,-2.808,-0.398,,0.554,.,b,0.55,0.68,9.913,9.913,71.59,BHO,-2.154,0.168804,0.00717253,1.1942 kka2_1:8_P45R,kka2_1:8_45,Kka2,kka2_1:8,P00552,1.1942,NO,45,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.774,-3.184,1.41,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.100394,0.00590481,1.1942 kka2_1:8_P45R,kka2_1:8_45,Kka2,kka2_1:8,P00552,1.1942,NO,45,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.774,-3.184,1.41,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.100394,0.00590481,1.1942 beta-lactamase_0_L196H,beta-lactamase_0_196,TEM-1,beta-lactamase_0,P62593,1.19433,NO,196,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-2.478,-3.478,1,,0.518,S,A,0.55,1.35,6.513,6.513,77.62,AHH,-1.839,0.0500837,0.00512144,1.19433 kka2_1:2_T225C,kka2_1:2_225,Kka2,kka2_1:2,P00552,1.19438,NO,225,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.393,-1.895,-0.498,,0.036,H,A,0.22,-1.22,4.554,,63.64,HPB,-1.58733,0.295029,0.0113598,1.19438 beta-lactamase_0_I258N,beta-lactamase_0_258,TEM-1,beta-lactamase_0,P62593,1.19451,NO,258,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.0500837,0.007931,1.19451 kka2_1:2_H8C,kka2_1:2_8,Kka2,kka2_1:2,P00552,1.19459,NO,8,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-2.759,-2.768,0.009,,,,,,,,,71.59,HBH,-2.25467,0.295029,0.00256422,1.19459 kka2_1:4_T72D,kka2_1:4_72,Kka2,kka2_1:4,P00552,1.19471,NO,72,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.38,-3.042,0.662,,0.784,H,A,0.82,0.29,6.463,,65.53,HPP,-2.238,0.168804,0.00750756,1.19471 kka2_1:4_A176M,kka2_1:4_176,Kka2,kka2_1:4,P00552,1.19472,NO,176,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.621,-4.76,3.139,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.168804,0.0083587,1.19472 kka2_1:4_G55S,kka2_1:4_55,Kka2,kka2_1:4,P00552,1.19478,NO,55,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.625,-2.154,0.529,,0.517,S,b,0.75,1.19,15.753,15.753,63.64,POH,-2.05967,0.168804,0.00667877,1.19478 gb1_D266Y,gb1_266,gb1,gb1,P06654,1.19497,NO,266,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.261,-2.205,0.944,,,,,,,0.638,,45.54,HAO,-1.59333,0.177985,0.00394694,1.19497 WW_domain_D170K,WW_domain_170,Yap65,WW_domain,P46937,1.19499,NO,170,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.213,-3.146,1.933,,,,,,,0.399,,15.87,OAH,-1.38,0.153962,0.00123319,1.19499 kka2_1:2_Q163A,kka2_1:2_163,Kka2,kka2_1:2,P00552,1.19501,NO,163,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.162,-2.603,0.441,,0.58,T,B,0.64,1.85,3.888,,64.02,BPO,-1.78333,0.295029,0.00719507,1.19501 beta-lactamase_0_R118Q,beta-lactamase_0_118,TEM-1,beta-lactamase_0,P62593,1.19503,NO,118,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.413,-3.932,1.519,,0.457,H,A,1.2,1.39,3.961,,77.62,HBA,-1.785,0.0500837,0.00538794,1.19503 beta-lactamase_0_R162M,beta-lactamase_0_162,TEM-1,beta-lactamase_0,P62593,1.19521,NO,162,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.016,-4.454,3.438,,0.124,S,B,1.2,-0.37,1.026,,64.69,ABH,-1.25,0.0500837,0.000561334,1.19521 kka2_1:2_I2C,kka2_1:2_2,Kka2,kka2_1:2,P00552,1.19521,NO,2,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.787,-4.477,2.69,,,,,,,5.773,,71.59,HHA,-1.92433,0.295029,0.00246644,1.19521 kka2_1:4_V46E,kka2_1:4_46,Kka2,kka2_1:4,P00552,1.19522,NO,46,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-2.62,-3.655,1.035,,0.192,.,B,0.44,-1.12,9.564,,92.05,OHH,-1.88633,0.168804,0.00631301,1.19522 kka2_1:8_S40D,kka2_1:8_40,Kka2,kka2_1:8,P00552,1.19524,NO,40,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.645,-2.229,-0.416,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.100394,0.00693477,1.19524 kka2_1:8_S40D,kka2_1:8_40,Kka2,kka2_1:8,P00552,1.19524,NO,40,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.645,-2.229,-0.416,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.100394,0.00693477,1.19524 kka2_1:8_A168P,kka2_1:8_168,Kka2,kka2_1:8,P00552,1.19531,NO,168,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.989,-3.241,1.252,,0.67,H,A,0.46,0.15,11.329,11.329,64.39,OHA,-2.12933,0.100394,0.00806773,1.19531 kka2_1:8_A168P,kka2_1:8_168,Kka2,kka2_1:8,P00552,1.19531,NO,168,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.989,-3.241,1.252,,0.67,H,A,0.46,0.15,11.329,11.329,64.39,OHA,-2.12933,0.100394,0.00806773,1.19531 beta-lactamase_0_E272V,beta-lactamase_0_272,TEM-1,beta-lactamase_0,P62593,1.19532,NO,272,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.0500837,0.00545371,1.19532 kka2_1:4_T73H,kka2_1:4_73,Kka2,kka2_1:4,P00552,1.19532,NO,73,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.51,-3.503,0.993,,0.309,H,A,0.22,0.35,1.53,,56.06,PPO,-2.02333,0.168804,0.00628605,1.19532 beta-lactamase_0_P255C,beta-lactamase_0_255,TEM-1,beta-lactamase_0,P62593,1.19534,NO,255,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.0500837,0.00499612,1.19534 gb1_D266W,gb1_266,gb1,gb1,P06654,1.19535,NO,266,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.261,-4.791,3.53,,,,,,,0.638,,45.54,HAO,-1.59333,0.177985,0.00394694,1.19535 kka2_1:2_S11P,kka2_1:2_11,Kka2,kka2_1:2,P00552,1.19536,NO,11,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.322,-2.34,0.018,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.295029,0.00381691,1.19536 kka2_1:2_I29T,kka2_1:2_29,Kka2,kka2_1:2,P00552,1.1954,NO,29,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.692,-2.952,1.26,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.295029,0.00619521,1.1954 beta-lactamase_0_L196N,beta-lactamase_0_196,TEM-1,beta-lactamase_0,P62593,1.19549,NO,196,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-2.478,-3.953,1.475,,0.518,S,A,0.55,1.35,6.513,6.513,77.62,AHH,-1.839,0.0500837,0.00512144,1.19549 kka2_1:4_D154N,kka2_1:4_154,Kka2,kka2_1:4,P00552,1.19553,NO,154,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.876,-2.341,1.465,,0.457,,b,0.29,1.48,15.641,15.641,52.65,HAP,-1.52467,0.168804,0.00292633,1.19553 kka2_1:4_E149Q,kka2_1:4_149,Kka2,kka2_1:4,P00552,1.19554,NO,149,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.994,-2.493,0.499,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.168804,0.00803343,1.19554 kka2_1:4_L7Q,kka2_1:4_7,Kka2,kka2_1:4,P00552,1.19563,NO,7,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.926,-3.782,1.856,,,,,,,3.012,,71.59,OHB,-2.12333,0.168804,0.00269456,1.19563 kka2_1:4_D62E,kka2_1:4_62,Kka2,kka2_1:4,P00552,1.19579,NO,62,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.591,-2.795,1.204,,0.262,H,A,0.29,0.08,14.756,14.756,64.39,PAA,-1.77833,0.168804,0.00744243,1.19579 kka2_1:8_Q100A,kka2_1:8_100,Kka2,kka2_1:8,P00552,1.19583,NO,100,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.77,-2.603,-0.167,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.100394,0.0066405,1.19583 kka2_1:8_Q100A,kka2_1:8_100,Kka2,kka2_1:8,P00552,1.19583,NO,100,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.77,-2.603,-0.167,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.100394,0.0066405,1.19583 beta-lactamase_0_R239H,beta-lactamase_0_239,TEM-1,beta-lactamase_0,P62593,1.19593,NO,239,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.0500837,0.00213852,1.19593 kka2_1:1_V46A,kka2_1:1_46,Kka2,kka2_1:1,P00552,1.19604,NO,46,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-2.62,-2.194,-0.426,,0.192,.,B,0.44,-1.12,20.149,20.149,92.05,OHH,-1.88633,0.520039,0.00631301,1.19604 kka2_1:8_R18N,kka2_1:8_18,Kka2,kka2_1:8,P00552,1.19605,NO,18,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.055,-3.899,1.844,,0.474,T,A,1.2,0.54,19.629,19.629,71.59,ABH,-1.821,0.100394,0.00724065,1.19605 kka2_1:8_R18N,kka2_1:8_18,Kka2,kka2_1:8,P00552,1.19605,NO,18,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.055,-3.899,1.844,,0.474,T,A,1.2,0.54,19.629,19.629,71.59,ABH,-1.821,0.100394,0.00724065,1.19605 kka2_1:4_G21T,kka2_1:4_21,Kka2,kka2_1:4,P00552,1.1961,NO,21,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.368,-3.639,2.271,,0.586,T,l,0.75,-0.75,3.075,,71.59,HOH,-2.10167,0.168804,0.00709648,1.1961 kka2_1:4_C209V,kka2_1:4_209,Kka2,kka2_1:4,P00552,1.19613,NO,209,C,V,CV,Special,Hydrophobic,5.07,5.60847,0.538465,192,121,117,-4,108.5,140,31.5,-0.906,-3.299,2.393,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.168804,0.00260862,1.19613 kka2_1:8_G74P,kka2_1:8_74,Kka2,kka2_1:8,P00552,1.19613,NO,74,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.18,-3.953,2.773,,0.621,T,l,0.29,0.2,2.014,,64.39,POH,-1.91667,0.100394,0.00587035,1.19613 kka2_1:8_G74P,kka2_1:8_74,Kka2,kka2_1:8,P00552,1.19613,NO,74,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.18,-3.953,2.773,,0.621,T,l,0.29,0.2,2.014,,64.39,POH,-1.91667,0.100394,0.00587035,1.19613 kka2_1:8_L126I,kka2_1:8_126,Kka2,kka2_1:8,P00552,1.19617,NO,126,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.246,-2.028,0.782,,0.285,S,B,1.59,0.12,4.443,,51.89,PHA,-1.744,0.100394,0.0066485,1.19617 kka2_1:8_L126I,kka2_1:8_126,Kka2,kka2_1:8,P00552,1.19617,NO,126,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.246,-2.028,0.782,,0.285,S,B,1.59,0.12,4.443,,51.89,PHA,-1.744,0.100394,0.0066485,1.19617 kka2_1:8_G10M,kka2_1:8_10,Kka2,kka2_1:8,P00552,1.19618,NO,10,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.921,-4.699,2.778,,,,,,,1.862,,71.59,HOP,-2.10733,0.100394,0.00289233,1.19618 kka2_1:8_G10M,kka2_1:8_10,Kka2,kka2_1:8,P00552,1.19618,NO,10,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.921,-4.699,2.778,,,,,,,1.862,,71.59,HOP,-2.10733,0.100394,0.00289233,1.19618 PSD95pdz3_P311W,PSD95pdz3_311,PSD95pdz3,PSD95pdz3,P31016,1.1962,NO,311,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.236,-5.229,3.993,5.76649,,,,,14.78,,,,OOB,-1.409,0.0758425,0.0030796,1.1962 kka2_1:8_H106R,kka2_1:8_106,Kka2,kka2_1:8,P00552,1.19633,NO,106,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-3.13,-2.944,-0.186,,1.065,,a,0.87,-0.95,15.956,15.956,71.59,PBH,-2.10433,0.100394,0.00730778,1.19633 kka2_1:8_H106R,kka2_1:8_106,Kka2,kka2_1:8,P00552,1.19633,NO,106,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-3.13,-2.944,-0.186,,1.065,,a,0.87,-0.95,15.956,15.956,71.59,PBH,-2.10433,0.100394,0.00730778,1.19633 kka2_1:8_Q155N,kka2_1:8_155,Kka2,kka2_1:8,P00552,1.19638,NO,155,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.606,-3.65,1.044,,0.525,T,A,0.64,1.49,,,63.64,APA,-1.726,0.100394,0.00641853,1.19638 kka2_1:8_Q155N,kka2_1:8_155,Kka2,kka2_1:8,P00552,1.19638,NO,155,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.606,-3.65,1.044,,0.525,T,A,0.64,1.49,,,63.64,APA,-1.726,0.100394,0.00641853,1.19638 beta-lactamase_0_E238Q,beta-lactamase_0_238,TEM-1,beta-lactamase_0,P62593,1.19646,NO,238,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.0500837,0.00743256,1.19646 kka2_1:8_E235V,kka2_1:8_235,Kka2,kka2_1:8,P00552,1.19647,NO,235,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.955,-2.86,0.905,,0.631,H,A,1.52,0.12,,,65.53,OAH,-2.07267,0.100394,0.0102806,1.19647 kka2_1:8_E235V,kka2_1:8_235,Kka2,kka2_1:8,P00552,1.19647,NO,235,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.955,-2.86,0.905,,0.631,H,A,1.52,0.12,,,65.53,OAH,-2.07267,0.100394,0.0102806,1.19647 kka2_1:8_V80M,kka2_1:8_80,Kka2,kka2_1:8,P00552,1.1965,NO,80,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.144,-4.231,3.087,,0.358,E,B,1.48,-0.24,2.562,,63.64,HHH,-1.64633,0.100394,0.00488211,1.1965 kka2_1:8_V80M,kka2_1:8_80,Kka2,kka2_1:8,P00552,1.1965,NO,80,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.144,-4.231,3.087,,0.358,E,B,1.48,-0.24,2.562,,63.64,HHH,-1.64633,0.100394,0.00488211,1.1965 PSD95pdz3_P311H,PSD95pdz3_311,PSD95pdz3,PSD95pdz3,P31016,1.19652,NO,311,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.236,-4.362,3.126,5.76649,,,,,14.78,,,,OOB,-1.409,0.0758425,0.0030796,1.19652 kka2_1:8_Q163D,kka2_1:8_163,Kka2,kka2_1:8,P00552,1.19653,NO,163,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.162,-3.807,1.645,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.100394,0.00719507,1.19653 kka2_1:8_Q163D,kka2_1:8_163,Kka2,kka2_1:8,P00552,1.19653,NO,163,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.162,-3.807,1.645,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.100394,0.00719507,1.19653 kka2_1:8_E160A,kka2_1:8_160,Kka2,kka2_1:8,P00552,1.19654,NO,160,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.683,-2.356,0.673,,0.989,G,A,1.04,2.28,2.164,,71.59,AAA,-1.36133,0.100394,0.00935762,1.19654 kka2_1:8_E160A,kka2_1:8_160,Kka2,kka2_1:8,P00552,1.19654,NO,160,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.683,-2.356,0.673,,0.989,G,A,1.04,2.28,2.164,,71.59,AAA,-1.36133,0.100394,0.00935762,1.19654 kka2_1:4_D52N,kka2_1:4_52,Kka2,kka2_1:4,P00552,1.19655,NO,52,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.271,-3.474,1.203,,0.22,E,B,0.75,0.8,0.349,,71.59,PAH,-2.38367,0.168804,0.00175694,1.19655 beta-lactamase_0_W163I,beta-lactamase_0_163,TEM-1,beta-lactamase_0,P62593,1.19659,NO,163,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-1.843,-3.136,1.293,,0.467,,B,0.47,-0.5,13.843,13.843,63.99,BHA,-1.269,0.0500837,0.00418955,1.19659 kka2_1:8_A248V,kka2_1:8_248,Kka2,kka2_1:8,P00552,1.19672,NO,248,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.124,-2.592,0.468,,0.825,S,b,1.04,0.46,11.329,11.329,92.05,HHO,-2.15,0.100394,0.0125484,1.19672 kka2_1:8_A248V,kka2_1:8_248,Kka2,kka2_1:8,P00552,1.19672,NO,248,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.124,-2.592,0.468,,0.825,S,b,1.04,0.46,11.329,11.329,92.05,HHO,-2.15,0.100394,0.0125484,1.19672 kka2_1:2_T28A,kka2_1:2_28,Kka2,kka2_1:2,P00552,1.19678,NO,28,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.883,-2.105,0.222,,0.353,S,B,0.22,2.02,2.655,,63.64,PPH,-1.74467,0.295029,0.00743084,1.19678 kka2_1:2_G43K,kka2_1:2_43,Kka2,kka2_1:2,P00552,1.19684,NO,43,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.587,-3.606,2.019,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.295029,0.0071925,1.19684 kka2_1:4_R173H,kka2_1:4_173,Kka2,kka2_1:4,P00552,1.19692,NO,173,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.407,-4.589,2.182,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.168804,0.00784999,1.19692 kka2_1:4_I2P,kka2_1:4_2,Kka2,kka2_1:4,P00552,1.19693,NO,2,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.787,-3.734,1.947,,,,,,,,,71.59,HHA,-1.92433,0.168804,0.00246644,1.19693 beta-lactamase_0_I277L,beta-lactamase_0_277,TEM-1,beta-lactamase_0,P62593,1.197,NO,277,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.869,,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.0500837,0.0169305,1.197 kka2_1:8_A41N,kka2_1:8_41,Kka2,kka2_1:8,P00552,1.19702,NO,41,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.879,-3.231,1.352,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.100394,0.00543332,1.19702 kka2_1:8_A41N,kka2_1:8_41,Kka2,kka2_1:8,P00552,1.19702,NO,41,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.879,-3.231,1.352,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.100394,0.00543332,1.19702 kka2_1:4_G43T,kka2_1:4_43,Kka2,kka2_1:4,P00552,1.19709,NO,43,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.587,-2.998,1.411,,0.862,T,l,0.75,-0.67,2.247,,63.26,POB,-2.18533,0.168804,0.0071925,1.19709 kka2_1:8_A176Q,kka2_1:8_176,Kka2,kka2_1:8,P00552,1.19709,NO,176,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.621,-3.141,1.52,,0.806,H,A,0.46,-0.03,18.904,18.904,65.53,BHB,-2.26667,0.100394,0.0083587,1.19709 kka2_1:8_A176Q,kka2_1:8_176,Kka2,kka2_1:8,P00552,1.19709,NO,176,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.621,-3.141,1.52,,0.806,H,A,0.46,-0.03,18.904,18.904,65.53,BHB,-2.26667,0.100394,0.0083587,1.19709 kka2_1:8_D52G,kka2_1:8_52,Kka2,kka2_1:8,P00552,1.19709,NO,52,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.271,-3.385,1.114,,0.22,E,B,0.75,0.8,5.447,,71.59,PAH,-2.38367,0.100394,0.00175694,1.19709 kka2_1:8_D52G,kka2_1:8_52,Kka2,kka2_1:8,P00552,1.19709,NO,52,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.271,-3.385,1.114,,0.22,E,B,0.75,0.8,5.447,,71.59,PAH,-2.38367,0.100394,0.00175694,1.19709 beta-lactamase_0_I280A,beta-lactamase_0_280,TEM-1,beta-lactamase_0,P62593,1.1972,NO,280,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.708,-4.017,2.309,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.0500837,0.0530888,1.1972 kka2_1:4_E149W,kka2_1:4_149,Kka2,kka2_1:4,P00552,1.19726,NO,149,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.994,-5.569,3.575,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.168804,0.00803343,1.19726 kka2_1:4_G234V,kka2_1:4_234,Kka2,kka2_1:4,P00552,1.19738,NO,234,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-2.9,-2.894,-0.006,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.168804,0.00984449,1.19738 kka2_1:8_R202M,kka2_1:8_202,Kka2,kka2_1:8,P00552,1.19742,NO,202,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.761,-4.784,3.023,,0.607,E,B,1.2,0.48,1.409,,52.27,OBH,-1.41067,0.100394,0.00696498,1.19742 kka2_1:8_R202M,kka2_1:8_202,Kka2,kka2_1:8,P00552,1.19742,NO,202,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.761,-4.784,3.023,,0.607,E,B,1.2,0.48,1.409,,52.27,OBH,-1.41067,0.100394,0.00696498,1.19742 kka2_1:4_A78P,kka2_1:4_78,Kka2,kka2_1:4,P00552,1.19751,NO,78,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.744,-0.97,-0.774,,0.078,.,B,0.46,-0.53,0.594,,56.06,OHH,-1.863,0.168804,0.00457299,1.19751 kka2_1:4_R18E,kka2_1:4_18,Kka2,kka2_1:4,P00552,1.19751,NO,18,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.055,-2.876,0.821,,0.474,T,A,1.2,0.54,8.405,8.405,71.59,ABH,-1.821,0.168804,0.00724065,1.19751 kka2_1:8_P76E,kka2_1:8_76,Kka2,kka2_1:8,P00552,1.19765,NO,76,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.449,-2.905,1.456,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.100394,0.00625685,1.19765 kka2_1:8_P76E,kka2_1:8_76,Kka2,kka2_1:8,P00552,1.19765,NO,76,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.449,-2.905,1.456,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.100394,0.00625685,1.19765 kka2_1:2_A247G,kka2_1:2_247,Kka2,kka2_1:2,P00552,1.19775,NO,247,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.459,-2.518,0.059,,1.01,S,A,0.46,0.65,0.828,,92.05,HHH,-2.197,0.295029,0.0102428,1.19775 kka2_1:8_Q100S,kka2_1:8_100,Kka2,kka2_1:8,P00552,1.19785,NO,100,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.77,-2.33,-0.44,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.100394,0.0066405,1.19785 kka2_1:8_Q100S,kka2_1:8_100,Kka2,kka2_1:8,P00552,1.19785,NO,100,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.77,-2.33,-0.44,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.100394,0.0066405,1.19785 kka2_1:4_T51S,kka2_1:4_51,Kka2,kka2_1:4,P00552,1.19788,NO,51,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.199,-2.009,-0.19,,0.05,E,B,0.82,-0.05,13.165,13.165,63.64,BPA,-1.76767,0.168804,0.00628861,1.19788 beta-lactamase_0_I206C,beta-lactamase_0_206,TEM-1,beta-lactamase_0,P62593,1.19791,NO,206,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-2.429,-4.969,2.54,,0.173,H,A,0.48,-0.34,3.411,,77.62,HHA,-1.805,0.0500837,0.00528934,1.19791 kka2_1:8_V80S,kka2_1:8_80,Kka2,kka2_1:8,P00552,1.19804,NO,80,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.144,-3.612,2.468,,0.358,E,B,1.48,-0.24,2.562,,63.64,HHH,-1.64633,0.100394,0.00488211,1.19804 kka2_1:8_V80S,kka2_1:8_80,Kka2,kka2_1:8,P00552,1.19804,NO,80,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.144,-3.612,2.468,,0.358,E,B,1.48,-0.24,2.562,,63.64,HHH,-1.64633,0.100394,0.00488211,1.19804 kka2_1:2_A176M,kka2_1:2_176,Kka2,kka2_1:2,P00552,1.19806,NO,176,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.621,-4.76,3.139,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.295029,0.0083587,1.19806 kka2_1:4_Q27L,kka2_1:4_27,Kka2,kka2_1:4,P00552,1.19808,NO,27,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-1.659,-2.589,0.93,,0.608,,A,0.4,0.71,1.498,,65.53,PPP,-1.90733,0.168804,0.00595365,1.19808 kka2_1:8_R253K,kka2_1:8_253,Kka2,kka2_1:8,P00552,1.19819,NO,253,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.356,-1.563,0.207,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.100394,0.0144195,1.19819 kka2_1:8_R253K,kka2_1:8_253,Kka2,kka2_1:8,P00552,1.19819,NO,253,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.356,-1.563,0.207,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.100394,0.0144195,1.19819 kka2_1:4_V80T,kka2_1:4_80,Kka2,kka2_1:4,P00552,1.19821,NO,80,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.144,-3.381,2.237,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.168804,0.00488211,1.19821 kka2_1:4_A172G,kka2_1:4_172,Kka2,kka2_1:4,P00552,1.19827,NO,172,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.757,-2.418,0.661,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.168804,0.0079265,1.19827 kka2_1:2_Q61S,kka2_1:2_61,Kka2,kka2_1:2,P00552,1.19832,NO,61,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.982,-2.728,-0.254,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.295029,0.00612092,1.19832 kka2_1:8_A110M,kka2_1:8_110,Kka2,kka2_1:8,P00552,1.19844,NO,110,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.064,-3.65,1.586,,0.175,H,A,1.04,-1.19,11.413,11.413,71.59,OHA,-1.91867,0.100394,0.00759851,1.19844 kka2_1:8_A110M,kka2_1:8_110,Kka2,kka2_1:8,P00552,1.19844,NO,110,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.064,-3.65,1.586,,0.175,H,A,1.04,-1.19,11.413,11.413,71.59,OHA,-1.91867,0.100394,0.00759851,1.19844 kka2_1:2_A110E,kka2_1:2_110,Kka2,kka2_1:2,P00552,1.19849,NO,110,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.064,-2.266,0.202,,0.175,H,A,0.46,-1.19,23.237,23.237,71.59,OHA,-1.91867,0.295029,0.00759851,1.19849 kka2_1:4_K138V,kka2_1:4_138,Kka2,kka2_1:4,P00552,1.19849,NO,138,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-2.5,-3.083,0.583,,0.594,H,A,1.3,0.98,21.267,21.267,71.59,HBB,-2.48833,0.168804,0.00628542,1.19849 beta-lactamase_0_R220N,beta-lactamase_0_220,TEM-1,beta-lactamase_0,P62593,1.19851,NO,220,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-0.942,-3.516,2.574,,0.295,I,A,1.2,-0.76,21.573,21.573,74.48,HBP,-1.33633,0.0500837,0.00232421,1.19851 kka2_1:4_I141T,kka2_1:4_141,Kka2,kka2_1:4,P00552,1.19854,NO,141,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.495,-3.551,2.056,,0.068,H,A,0.48,-0.01,2.144,,92.05,BHA,-1.689,0.168804,0.00744745,1.19854 kka2_1:8_G181T,kka2_1:8_181,Kka2,kka2_1:8,P00552,1.1987,NO,181,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-2.698,-2.358,-0.34,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.100394,0.00728319,1.1987 kka2_1:8_G181T,kka2_1:8_181,Kka2,kka2_1:8,P00552,1.1987,NO,181,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-2.698,-2.358,-0.34,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.100394,0.00728319,1.1987 kka2_1:8_A79G,kka2_1:8_79,Kka2,kka2_1:8,P00552,1.19871,NO,79,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.368,-2.844,0.476,,0.563,.,B,0.46,-0.43,,,71.59,HHH,-1.752,0.100394,0.00664821,1.19871 kka2_1:8_A79G,kka2_1:8_79,Kka2,kka2_1:8,P00552,1.19871,NO,79,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.368,-2.844,0.476,,0.563,.,B,0.46,-0.43,,,71.59,HHH,-1.752,0.100394,0.00664821,1.19871 kka2_1:8_D23I,kka2_1:8_23,Kka2,kka2_1:8,P00552,1.19872,NO,23,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.459,-4.001,1.542,,0.695,E,B,0.75,-0.65,,,65.53,HAH,-1.94033,0.100394,0.007195,1.19872 kka2_1:8_D23I,kka2_1:8_23,Kka2,kka2_1:8,P00552,1.19872,NO,23,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.459,-4.001,1.542,,0.695,E,B,0.75,-0.65,,,65.53,HAH,-1.94033,0.100394,0.007195,1.19872 beta-lactamase_0_V72M,beta-lactamase_0_72,TEM-1,beta-lactamase_0,P62593,1.19881,NO,72,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.658,-4.404,2.746,,,H,A,0.44,-1.03,2.964,,65.73,BHH,-1.32167,0.0500837,0.00501194,1.19881 kka2_1:8_A129W,kka2_1:8_129,Kka2,kka2_1:8,P00552,1.19885,NO,129,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.656,-5.587,3.931,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.100394,0.00726862,1.19885 kka2_1:8_A129W,kka2_1:8_129,Kka2,kka2_1:8,P00552,1.19885,NO,129,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.656,-5.587,3.931,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.100394,0.00726862,1.19885 kka2_1:1_Q4L,kka2_1:1_4,Kka2,kka2_1:1,P00552,1.19887,NO,4,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.361,-3.406,1.045,,,,,,,5.615,,71.59,APA,-1.95533,0.520039,0.00239179,1.19887 kka2_1:8_R253Q,kka2_1:8_253,Kka2,kka2_1:8,P00552,1.19888,NO,253,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.356,-3.67,2.314,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.100394,0.0144195,1.19888 kka2_1:8_R253Q,kka2_1:8_253,Kka2,kka2_1:8,P00552,1.19888,NO,253,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.356,-3.67,2.314,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.100394,0.0144195,1.19888 kka2_1:4_A166M,kka2_1:4_166,Kka2,kka2_1:4,P00552,1.19889,NO,166,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.407,-4.784,2.377,,0.534,.,B,0.46,1.03,,,71.59,HHO,-2.421,0.168804,0.00799912,1.19889 kka2_1:8_A168T,kka2_1:8_168,Kka2,kka2_1:8,P00552,1.19889,NO,168,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.989,-2.711,0.722,,0.67,H,A,0.46,0.15,11.329,11.329,64.39,OHA,-2.12933,0.100394,0.00806773,1.19889 kka2_1:8_A168T,kka2_1:8_168,Kka2,kka2_1:8,P00552,1.19889,NO,168,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.989,-2.711,0.722,,0.67,H,A,0.46,0.15,11.329,11.329,64.39,OHA,-2.12933,0.100394,0.00806773,1.19889 kka2_1:8_A25R,kka2_1:8_25,Kka2,kka2_1:8,P00552,1.19889,NO,25,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.496,-2.407,-0.089,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.100394,0.00595636,1.19889 kka2_1:8_A25R,kka2_1:8_25,Kka2,kka2_1:8,P00552,1.19889,NO,25,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.496,-2.407,-0.089,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.100394,0.00595636,1.19889 kka2_1:8_L259I,kka2_1:8_259,Kka2,kka2_1:8,P00552,1.19905,NO,259,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.088,-3.1,2.012,,0.036,H,A,1.59,-0.15,1.83,,48.48,BHH,-1.15167,0.100394,0.0206964,1.19905 kka2_1:8_L259I,kka2_1:8_259,Kka2,kka2_1:8,P00552,1.19905,NO,259,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.088,-3.1,2.012,,0.036,H,A,1.59,-0.15,1.83,,48.48,BHH,-1.15167,0.100394,0.0206964,1.19905 kka2_1:1_Q4M,kka2_1:1_4,Kka2,kka2_1:1,P00552,1.19908,NO,4,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.361,-4.464,2.103,,,,,,,5.615,,71.59,APA,-1.95533,0.520039,0.00239179,1.19908 kka2_1:4_M178R,kka2_1:4_178,Kka2,kka2_1:4,P00552,1.19912,NO,178,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-3.206,-1.763,-1.443,,0.554,.,b,0.55,0.68,9.913,9.913,71.59,BHO,-2.154,0.168804,0.00717253,1.19912 kka2_1:8_C209A,kka2_1:8_209,Kka2,kka2_1:8,P00552,1.19915,NO,209,C,A,CA,Special,Hydrophobic,5.07,6,0.93,195,121,89,-32,108.5,88.6,-19.9,-0.906,-2.925,2.019,,,,a,1.5,-0.89,0.391,,19.32,AOO,-0.903,0.100394,0.00260862,1.19915 kka2_1:8_C209A,kka2_1:8_209,Kka2,kka2_1:8,P00552,1.19915,NO,209,C,A,CA,Special,Hydrophobic,5.07,6,0.93,195,121,89,-32,108.5,88.6,-19.9,-0.906,-2.925,2.019,,,,a,1.5,-0.89,0.391,,19.32,AOO,-0.903,0.100394,0.00260862,1.19915 kka2_1:8_P249I,kka2_1:8_249,Kka2,kka2_1:8,P00552,1.19929,NO,249,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.867,-2.381,0.514,,0.406,.,B,0.52,-0.01,1.699,,92.05,HOA,-1.66867,0.100394,0.011045,1.19929 kka2_1:8_P249I,kka2_1:8_249,Kka2,kka2_1:8,P00552,1.19929,NO,249,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.867,-2.381,0.514,,0.406,.,B,0.52,-0.01,1.699,,92.05,HOA,-1.66867,0.100394,0.011045,1.19929 kka2_1:1_G6D,kka2_1:1_6,Kka2,kka2_1:1,P00552,1.19931,NO,6,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.685,-3.441,1.756,,,,,,,1.292,,71.59,AOH,-1.639,0.520039,0.00204693,1.19931 kka2_1:8_I141T,kka2_1:8_141,Kka2,kka2_1:8,P00552,1.19933,NO,141,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.495,-3.551,2.056,,0.068,H,A,1.52,-0.01,2.144,,92.05,BHA,-1.689,0.100394,0.00744745,1.19933 kka2_1:8_I141T,kka2_1:8_141,Kka2,kka2_1:8,P00552,1.19933,NO,141,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.495,-3.551,2.056,,0.068,H,A,1.52,-0.01,2.144,,92.05,BHA,-1.689,0.100394,0.00744745,1.19933 beta-lactamase_0_G236I,beta-lactamase_0_236,TEM-1,beta-lactamase_0,P62593,1.19938,NO,236,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.784,-4.139,3.355,,0.241,,b,0.29,-0.59,3.506,,64.69,HOO,-1.025,0.0500837,0.00162372,1.19938 kka2_1:8_T73Q,kka2_1:8_73,Kka2,kka2_1:8,P00552,1.19938,NO,73,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.51,-1.983,-0.527,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.100394,0.00628605,1.19938 kka2_1:8_T73Q,kka2_1:8_73,Kka2,kka2_1:8,P00552,1.19938,NO,73,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.51,-1.983,-0.527,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.100394,0.00628605,1.19938 kka2_1:2_A87G,kka2_1:2_87,Kka2,kka2_1:2,P00552,1.19946,NO,87,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.917,-2.002,0.085,,1.039,S,L,0.46,1.57,22.675,22.675,65.53,AHO,-1.822,0.295029,0.00791281,1.19946 kka2_1:8_A168N,kka2_1:8_168,Kka2,kka2_1:8,P00552,1.19949,NO,168,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.989,-3.164,1.175,,0.67,H,A,0.46,0.15,11.329,11.329,64.39,OHA,-2.12933,0.100394,0.00806773,1.19949 kka2_1:8_A168N,kka2_1:8_168,Kka2,kka2_1:8,P00552,1.19949,NO,168,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.989,-3.164,1.175,,0.67,H,A,0.46,0.15,11.329,11.329,64.39,OHA,-2.12933,0.100394,0.00806773,1.19949 kka2_1:8_L152F,kka2_1:8_152,Kka2,kka2_1:8,P00552,1.19951,NO,152,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.521,-4.081,2.56,,0.547,.,A,0.55,1.36,1.442,,63.64,OHH,-1.162,0.100394,0.00674868,1.19951 kka2_1:8_L152F,kka2_1:8_152,Kka2,kka2_1:8,P00552,1.19951,NO,152,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.521,-4.081,2.56,,0.547,.,A,0.55,1.36,1.442,,63.64,OHH,-1.162,0.100394,0.00674868,1.19951 kka2_1:8_C31E,kka2_1:8_31,Kka2,kka2_1:8,P00552,1.19953,NO,31,C,E,CE,Special,negativeCharge,5.07,3.22,-1.85,170,121,147,26,108.5,138.4,29.9,-2.246,-1.966,-0.28,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.100394,0.00681582,1.19953 kka2_1:8_C31E,kka2_1:8_31,Kka2,kka2_1:8,P00552,1.19953,NO,31,C,E,CE,Special,negativeCharge,5.07,3.22,-1.85,170,121,147,26,108.5,138.4,29.9,-2.246,-1.966,-0.28,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.100394,0.00681582,1.19953 kka2_1:8_A172Q,kka2_1:8_172,Kka2,kka2_1:8,P00552,1.19965,NO,172,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.757,-3.279,1.522,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.100394,0.0079265,1.19965 kka2_1:8_A172Q,kka2_1:8_172,Kka2,kka2_1:8,P00552,1.19965,NO,172,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.757,-3.279,1.522,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.100394,0.0079265,1.19965 beta-lactamase_0_K30P,beta-lactamase_0_30,TEM-1,beta-lactamase_0,P62593,1.19966,NO,30,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-2.307,-3.871,1.564,,0.142,H,A,2.34,-0.65,1.491,,93.01,HBH,-2.32833,0.0500837,0.00448593,1.19966 kka2_1:2_A41N,kka2_1:2_41,Kka2,kka2_1:2,P00552,1.19968,NO,41,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.879,-3.231,1.352,,0.184,.,B,0.46,-0.96,24.451,24.451,64.39,PHP,-2.477,0.295029,0.00543332,1.19968 kka2_1:8_Q26A,kka2_1:8_26,Kka2,kka2_1:8,P00552,1.19982,NO,26,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.18,-2.361,0.181,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.100394,0.00708962,1.19982 kka2_1:8_Q26A,kka2_1:8_26,Kka2,kka2_1:8,P00552,1.19982,NO,26,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.18,-2.361,0.181,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.100394,0.00708962,1.19982 kka2_1:4_A229Q,kka2_1:4_229,Kka2,kka2_1:4,P00552,1.19984,NO,229,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.739,-3.175,1.436,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.168804,0.00942138,1.19984 kka2_1:8_Q42K,kka2_1:8_42,Kka2,kka2_1:8,P00552,1.19984,NO,42,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.907,-2.899,-0.008,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.100394,0.00679212,1.19984 kka2_1:8_Q42K,kka2_1:8_42,Kka2,kka2_1:8,P00552,1.19984,NO,42,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.907,-2.899,-0.008,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.100394,0.00679212,1.19984 beta-lactamase_0_E46F,beta-lactamase_0_46,TEM-1,beta-lactamase_0,P62593,1.19995,NO,46,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.94,-4.056,2.116,,0.021,E,B,1.04,0.14,30.306,30.306,59.44,HAH,-2.079,0.0500837,0.00427568,1.19995 beta-lactamase_0_K30Q,beta-lactamase_0_30,TEM-1,beta-lactamase_0,P62593,1.20001,NO,30,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-2.307,-2.158,-0.149,,0.142,H,A,2.34,-0.65,1.491,,93.01,HBH,-2.32833,0.0500837,0.00448593,1.20001 kka2_1:4_E231Y,kka2_1:4_231,Kka2,kka2_1:4,P00552,1.20007,NO,231,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.002,-4.332,2.33,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.168804,0.00732383,1.20007 gb1_A250P,gb1_250,gb1,gb1,P06654,1.20011,NO,250,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.713,-3.572,1.859,,,,,,,3.465,,45.54,HHP,-1.74867,0.177985,0.00332003,1.20011 kka2_1:2_A247P,kka2_1:2_247,Kka2,kka2_1:2,P00552,1.20017,NO,247,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.459,-2.362,-0.097,,1.01,S,A,0.46,0.65,0.828,,92.05,HHH,-2.197,0.295029,0.0102428,1.20017 kka2_1:4_E111V,kka2_1:4_111,Kka2,kka2_1:4,P00552,1.2002,NO,111,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.28,-2.806,0.526,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.168804,0.00746789,1.2002 beta-lactamase_0_I93T,beta-lactamase_0_93,TEM-1,beta-lactamase_0,P62593,1.20025,NO,93,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.401,-2.729,1.328,,0.128,E,B,0.48,0.44,1.266,,67.83,BHB,-1.873,0.0500837,0.00527066,1.20025 kka2_1:4_A110Q,kka2_1:4_110,Kka2,kka2_1:4,P00552,1.2003,NO,110,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.064,-2.476,0.412,,0.175,H,A,0.46,-1.19,23.237,23.237,71.59,OHA,-1.91867,0.168804,0.00759851,1.2003 beta-lactamase_0_A148R,beta-lactamase_0_148,TEM-1,beta-lactamase_0,P62593,1.20037,NO,148,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.757,-2.456,0.699,,0.379,H,A,0.46,-0.55,19.42,19.42,72.73,PHH,-1.40167,0.0500837,0.00547053,1.20037 beta-lactamase_0_Q86C,beta-lactamase_0_86,TEM-1,beta-lactamase_0,P62593,1.20038,NO,86,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.4,-5.132,2.732,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.0500837,0.00450027,1.20038 kka2_1:4_A150K,kka2_1:4_150,Kka2,kka2_1:4,P00552,1.20039,NO,150,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.949,-3.494,2.545,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.168804,0.0045009,1.20039 kka2_1:8_T28M,kka2_1:8_28,Kka2,kka2_1:8,P00552,1.20041,NO,28,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.883,-3.567,1.684,,0.353,S,B,0.22,2.02,18.114,18.114,63.64,PPH,-1.74467,0.100394,0.00743084,1.20041 kka2_1:8_T28M,kka2_1:8_28,Kka2,kka2_1:8,P00552,1.20041,NO,28,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.883,-3.567,1.684,,0.353,S,B,0.22,2.02,18.114,18.114,63.64,PPH,-1.74467,0.100394,0.00743084,1.20041 kka2_1:2_A25H,kka2_1:2_25,Kka2,kka2_1:2,P00552,1.20043,NO,25,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.496,-3.145,0.649,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.295029,0.00595636,1.20043 beta-lactamase_0_S221D,beta-lactamase_0_221,TEM-1,beta-lactamase_0,P62593,1.20045,NO,221,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.754,-3.645,1.891,,0.624,H,A,0.27,-0.2,2.914,,74.48,BPH,-1.59967,0.0500837,0.0046094,1.20045 beta-lactamase_0_L223I,beta-lactamase_0_223,TEM-1,beta-lactamase_0,P62593,1.20046,NO,223,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.055,-2.996,1.941,,0.27,,B,0.55,0.09,1.633,,74.48,HHO,-1.35033,0.0500837,0.00372793,1.20046 kka2_1:8_V153M,kka2_1:8_153,Kka2,kka2_1:8,P00552,1.20049,NO,153,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.092,-4.165,3.073,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.100394,0.00501119,1.20049 kka2_1:8_V153M,kka2_1:8_153,Kka2,kka2_1:8,P00552,1.20049,NO,153,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.092,-4.165,3.073,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.100394,0.00501119,1.20049 kka2_1:4_Q61E,kka2_1:4_61,Kka2,kka2_1:4,P00552,1.2006,NO,61,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.982,-2.773,-0.209,,0.591,H,A,0.64,0.41,3.484,,65.53,HPA,-1.85667,0.168804,0.00612092,1.2006 kka2_1:2_P167V,kka2_1:2_167,Kka2,kka2_1:2,P00552,1.20065,NO,167,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-2.403,-2.424,0.021,,0.18,H,A,0.52,0.75,3.6,,64.39,HOH,-2.26633,0.295029,0.00543203,1.20065 kka2_1:2_T225V,kka2_1:2_225,Kka2,kka2_1:2,P00552,1.20066,NO,225,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.393,-2.516,0.123,,0.036,H,A,0.22,-1.22,4.554,,63.64,HPB,-1.58733,0.295029,0.0113598,1.20066 kka2_1:2_T130C,kka2_1:2_130,Kka2,kka2_1:2,P00552,1.2007,NO,130,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.392,-3.62,1.228,,0.561,G,A,0.22,0.77,0.5,,92.05,HPO,-1.62633,0.295029,0.00804204,1.2007 kka2_1:8_T73C,kka2_1:8_73,Kka2,kka2_1:8,P00552,1.20073,NO,73,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.51,-3.584,1.074,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.100394,0.00628605,1.20073 kka2_1:8_T73C,kka2_1:8_73,Kka2,kka2_1:8,P00552,1.20073,NO,73,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.51,-3.584,1.074,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.100394,0.00628605,1.20073 kka2_1:8_A247D,kka2_1:8_247,Kka2,kka2_1:8,P00552,1.20075,NO,247,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.459,-3.029,0.57,,1.01,S,A,0.46,0.65,18.904,18.904,92.05,HHH,-2.197,0.100394,0.0102428,1.20075 kka2_1:8_A247D,kka2_1:8_247,Kka2,kka2_1:8,P00552,1.20075,NO,247,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.459,-3.029,0.57,,1.01,S,A,0.46,0.65,18.904,18.904,92.05,HHH,-2.197,0.100394,0.0102428,1.20075 kka2_1:8_D23R,kka2_1:8_23,Kka2,kka2_1:8,P00552,1.20079,NO,23,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.459,-2.183,-0.276,,0.695,E,B,0.75,-0.65,,,65.53,HAH,-1.94033,0.100394,0.007195,1.20079 kka2_1:8_D23R,kka2_1:8_23,Kka2,kka2_1:8,P00552,1.20079,NO,23,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.459,-2.183,-0.276,,0.695,E,B,0.75,-0.65,,,65.53,HAH,-1.94033,0.100394,0.007195,1.20079 beta-lactamase_0_V78E,beta-lactamase_0_78,TEM-1,beta-lactamase_0,P62593,1.20085,NO,78,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.459,-3.911,2.452,,,H,A,0.44,-0.47,16.615,16.615,63.64,HHH,-1.17833,0.0500837,0.00492501,1.20085 kka2_1:8_S68C,kka2_1:8_68,Kka2,kka2_1:8,P00552,1.20088,NO,68,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.623,-3.588,0.965,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.100394,0.00608265,1.20088 kka2_1:8_S68C,kka2_1:8_68,Kka2,kka2_1:8,P00552,1.20088,NO,68,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.623,-3.588,0.965,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.100394,0.00608265,1.20088 kka2_1:4_G10F,kka2_1:4_10,Kka2,kka2_1:4,P00552,1.20092,NO,10,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.921,-4.367,2.446,,,,,,,1.862,,71.59,HOP,-2.10733,0.168804,0.00289233,1.20092 kka2_1:2_S40A,kka2_1:2_40,Kka2,kka2_1:2,P00552,1.20094,NO,40,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.645,-2.559,-0.086,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.295029,0.00693477,1.20094 kka2_1:2_A247L,kka2_1:2_247,Kka2,kka2_1:2,P00552,1.20097,NO,247,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.459,-2.722,0.263,,1.01,S,A,0.46,0.65,0.828,,92.05,HHH,-2.197,0.295029,0.0102428,1.20097 kka2_1:2_A14D,kka2_1:2_14,Kka2,kka2_1:2,P00552,1.20103,NO,14,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.837,-2.812,0.975,,0.728,G,A,0.46,0.7,0.36,,71.59,HHH,-1.82567,0.295029,0.00706614,1.20103 kka2_1:8_R177Q,kka2_1:8_177,Kka2,kka2_1:8,P00552,1.20104,NO,177,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.282,-3.061,0.779,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.100394,0.00768224,1.20104 kka2_1:8_R177Q,kka2_1:8_177,Kka2,kka2_1:8,P00552,1.20104,NO,177,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.282,-3.061,0.779,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.100394,0.00768224,1.20104 beta-lactamase_0_L205D,beta-lactamase_0_205,TEM-1,beta-lactamase_0,P62593,1.20114,NO,205,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.922,-4.118,3.196,,,H,A,0.55,-0.46,1.065,,42.31,PHH,-1.57767,0.0500837,0.00255802,1.20114 kka2_1:8_R202V,kka2_1:8_202,Kka2,kka2_1:8,P00552,1.20121,NO,202,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.761,-3.107,1.346,,0.607,E,B,1.2,0.48,1.409,,52.27,OBH,-1.41067,0.100394,0.00696498,1.20121 kka2_1:8_R202V,kka2_1:8_202,Kka2,kka2_1:8,P00552,1.20121,NO,202,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.761,-3.107,1.346,,0.607,E,B,1.2,0.48,1.409,,52.27,OBH,-1.41067,0.100394,0.00696498,1.20121 kka2_1:8_A150L,kka2_1:8_150,Kka2,kka2_1:8,P00552,1.20123,NO,150,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.949,-3.346,2.397,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.100394,0.0045009,1.20123 kka2_1:8_A150L,kka2_1:8_150,Kka2,kka2_1:8,P00552,1.20123,NO,150,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.949,-3.346,2.397,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.100394,0.0045009,1.20123 beta-lactamase_0_R189F,beta-lactamase_0_189,TEM-1,beta-lactamase_0,P62593,1.20127,NO,189,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.844,-4.275,2.431,,0.278,H,A,1.2,1.01,12.11,12.11,72.73,HBB,-1.668,0.0500837,0.0050699,1.20127 kka2_1:4_L53F,kka2_1:4_53,Kka2,kka2_1:4,P00552,1.20132,NO,53,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-2.681,-4.426,1.745,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.168804,0.00671168,1.20132 kka2_1:8_E17S,kka2_1:8_17,Kka2,kka2_1:8,P00552,1.20133,NO,17,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.154,-2.653,0.499,,0.957,T,A,1.04,0.22,31.483,31.483,63.64,HAB,-2.432,0.100394,0.00688738,1.20133 kka2_1:8_E17S,kka2_1:8_17,Kka2,kka2_1:8,P00552,1.20133,NO,17,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.154,-2.653,0.499,,0.957,T,A,1.04,0.22,31.483,31.483,63.64,HAB,-2.432,0.100394,0.00688738,1.20133 kka2_1:8_G181D,kka2_1:8_181,Kka2,kka2_1:8,P00552,1.20137,NO,181,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-2.698,-2.653,-0.045,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.100394,0.00728319,1.20137 kka2_1:8_G181D,kka2_1:8_181,Kka2,kka2_1:8,P00552,1.20137,NO,181,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-2.698,-2.653,-0.045,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.100394,0.00728319,1.20137 kka2_1:2_S251R,kka2_1:2_251,Kka2,kka2_1:2,P00552,1.2014,NO,251,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.636,-2.795,0.159,,0.712,H,A,0.27,-0.25,32.832,32.832,71.59,APP,-2.09367,0.295029,0.0138916,1.2014 kka2_1:8_P76A,kka2_1:8_76,Kka2,kka2_1:8,P00552,1.20146,NO,76,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.449,-1.98,0.531,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.100394,0.00625685,1.20146 kka2_1:8_P76A,kka2_1:8_76,Kka2,kka2_1:8,P00552,1.20146,NO,76,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.449,-1.98,0.531,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.100394,0.00625685,1.20146 beta-lactamase_0_H110R,beta-lactamase_0_110,TEM-1,beta-lactamase_0,P62593,1.20152,NO,110,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-1.706,-2.008,0.302,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.0500837,0.00441499,1.20152 kka2_1:4_V242H,kka2_1:4_242,Kka2,kka2_1:4,P00552,1.20174,NO,242,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-2.687,-3.504,0.817,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.168804,0.0102575,1.20174 kka2_1:8_V80A,kka2_1:8_80,Kka2,kka2_1:8,P00552,1.20174,NO,80,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.144,-2.287,1.143,,0.358,E,B,1.48,-0.24,2.562,,63.64,HHH,-1.64633,0.100394,0.00488211,1.20174 kka2_1:8_V80A,kka2_1:8_80,Kka2,kka2_1:8,P00552,1.20174,NO,80,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.144,-2.287,1.143,,0.358,E,B,1.48,-0.24,2.562,,63.64,HHH,-1.64633,0.100394,0.00488211,1.20174 beta-lactamase_0_F58D,beta-lactamase_0_58,TEM-1,beta-lactamase_0,P62593,1.20175,NO,58,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-2.914,-3.846,0.932,,0.266,E,B,0.58,-0.07,24.637,24.637,77.62,PHB,-2.059,0.0500837,0.00523369,1.20175 kka2_1:2_G181D,kka2_1:2_181,Kka2,kka2_1:2,P00552,1.20175,NO,181,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-2.698,-2.653,-0.045,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.295029,0.00728319,1.20175 kka2_1:8_A25F,kka2_1:8_25,Kka2,kka2_1:8,P00552,1.20175,NO,25,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.496,-4.408,1.912,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.100394,0.00595636,1.20175 kka2_1:8_A25F,kka2_1:8_25,Kka2,kka2_1:8,P00552,1.20175,NO,25,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.496,-4.408,1.912,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.100394,0.00595636,1.20175 beta-lactamase_0_G39H,beta-lactamase_0_39,TEM-1,beta-lactamase_0,P62593,1.20179,NO,39,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.864,-3.359,1.495,,0.701,T,L,0.29,0.47,4.111,,77.62,HOH,-1.53633,0.0500837,0.00487611,1.20179 kka2_1:2_T146S,kka2_1:2_146,Kka2,kka2_1:2,P00552,1.20185,NO,146,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.978,-2.727,-0.251,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.295029,0.00606474,1.20185 kka2_1:4_A25Q,kka2_1:4_25,Kka2,kka2_1:4,P00552,1.20186,NO,25,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.496,-2.581,0.085,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.168804,0.00595636,1.20186 kka2_1:4_E111H,kka2_1:4_111,Kka2,kka2_1:4,P00552,1.20189,NO,111,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.28,-3.298,1.018,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.168804,0.00746789,1.20189 kka2_1:4_T146K,kka2_1:4_146,Kka2,kka2_1:4,P00552,1.20189,NO,146,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.978,-2.607,-0.371,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.168804,0.00606474,1.20189 kka2_1:8_A79M,kka2_1:8_79,Kka2,kka2_1:8,P00552,1.20189,NO,79,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.368,-3.668,1.3,,0.563,.,B,0.46,-0.43,,,71.59,HHH,-1.752,0.100394,0.00664821,1.20189 kka2_1:8_A79M,kka2_1:8_79,Kka2,kka2_1:8,P00552,1.20189,NO,79,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.368,-3.668,1.3,,0.563,.,B,0.46,-0.43,,,71.59,HHH,-1.752,0.100394,0.00664821,1.20189 kka2_1:4_L152K,kka2_1:4_152,Kka2,kka2_1:4,P00552,1.20202,NO,152,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.521,-3.615,2.094,,0.547,,A,1.59,1.36,2.318,,63.64,OHH,-1.162,0.168804,0.00674868,1.20202 beta-lactamase_0_A77F,beta-lactamase_0_77,TEM-1,beta-lactamase_0,P62593,1.20203,NO,77,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.234,-4.125,2.891,,0.039,H,A,0.46,-0.56,2.591,,64.34,OHH,-1.294,0.0500837,0.00282362,1.20203 beta-lactamase_0_F58K,beta-lactamase_0_58,TEM-1,beta-lactamase_0,P62593,1.20208,NO,58,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-2.914,-3.623,0.709,,0.266,E,B,0.58,-0.07,24.637,24.637,77.62,PHB,-2.059,0.0500837,0.00523369,1.20208 kka2_1:4_I246E,kka2_1:4_246,Kka2,kka2_1:4,P00552,1.2021,NO,246,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-2.008,-3.889,1.881,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.168804,0.0139479,1.2021 beta-lactamase_0_E62A,beta-lactamase_0_62,TEM-1,beta-lactamase_0,P62593,1.20211,NO,62,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.193,-2.533,1.34,,0.342,S,B,1.04,-0.3,5.784,,73.08,AAB,-1.417,0.0500837,0.00264802,1.20211 kka2_1:4_L103K,kka2_1:4_103,Kka2,kka2_1:4,P00552,1.20221,NO,103,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-2.362,-3.65,1.288,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.168804,0.00574792,1.20221 kka2_1:4_A35W,kka2_1:4_35,Kka2,kka2_1:4,P00552,1.20235,NO,35,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.127,-5.562,3.435,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.168804,0.00630016,1.20235 kka2_1:4_A150N,kka2_1:4_150,Kka2,kka2_1:4,P00552,1.20253,NO,150,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.949,-3.852,2.903,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.168804,0.0045009,1.20253 kka2_1:4_D23G,kka2_1:4_23,Kka2,kka2_1:4,P00552,1.20253,NO,23,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.459,-2.651,0.192,,0.695,E,B,0.75,-0.65,2.416,,65.53,HAH,-1.94033,0.168804,0.007195,1.20253 kka2_1:4_P76A,kka2_1:4_76,Kka2,kka2_1:4,P00552,1.20255,NO,76,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.449,-1.98,0.531,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.168804,0.00625685,1.20255 kka2_1:4_T85A,kka2_1:4_85,Kka2,kka2_1:4,P00552,1.2026,NO,85,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.165,-2.833,0.668,,0.576,E,B,0.22,1.39,1.853,,71.59,HPA,-2.10133,0.168804,0.00634493,1.2026 kka2_1:8_F20Q,kka2_1:8_20,Kka2,kka2_1:8,P00552,1.20266,NO,20,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-3.354,-3.237,-0.117,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.100394,0.00701744,1.20266 kka2_1:8_F20Q,kka2_1:8_20,Kka2,kka2_1:8,P00552,1.20266,NO,20,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-3.354,-3.237,-0.117,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.100394,0.00701744,1.20266 kka2_1:8_L165V,kka2_1:8_165,Kka2,kka2_1:8,P00552,1.20266,NO,165,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-2.453,-2.841,0.388,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.100394,0.00801161,1.20266 kka2_1:8_L165V,kka2_1:8_165,Kka2,kka2_1:8,P00552,1.20266,NO,165,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-2.453,-2.841,0.388,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.100394,0.00801161,1.20266 kka2_1:8_E160H,kka2_1:8_160,Kka2,kka2_1:8,P00552,1.20269,NO,160,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.683,-4.581,2.898,,0.989,G,A,1.04,2.28,2.164,,71.59,AAA,-1.36133,0.100394,0.00935762,1.20269 kka2_1:8_E160H,kka2_1:8_160,Kka2,kka2_1:8,P00552,1.20269,NO,160,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.683,-4.581,2.898,,0.989,G,A,1.04,2.28,2.164,,71.59,AAA,-1.36133,0.100394,0.00935762,1.20269 gb1_A250E,gb1_250,gb1,gb1,P06654,1.20273,NO,250,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.713,-1.803,0.09,,,,,,,3.465,,45.54,HHP,-1.74867,0.177985,0.00332003,1.20273 kka2_1:4_E235V,kka2_1:4_235,Kka2,kka2_1:4,P00552,1.20273,NO,235,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.955,-2.86,0.905,,0.631,H,A,1.04,0.12,23.175,23.175,65.53,OAH,-2.07267,0.168804,0.0102806,1.20273 kka2_1:2_L165H,kka2_1:2_165,Kka2,kka2_1:2,P00552,1.20275,NO,165,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-2.453,-4.763,2.31,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.295029,0.00801161,1.20275 WW_domain_A180R,WW_domain_180,Yap65,WW_domain,P46937,1.2028,NO,180,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.242,-3.548,2.306,6.02829,,,,,,0.627,,23.61,HHB,-1.37767,0.153962,0.00413929,1.2028 kka2_1:8_R239H,kka2_1:8_239,Kka2,kka2_1:8,P00552,1.20281,NO,239,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.949,-2.896,-0.053,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.100394,0.00835326,1.20281 kka2_1:8_R239H,kka2_1:8_239,Kka2,kka2_1:8,P00552,1.20281,NO,239,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.949,-2.896,-0.053,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.100394,0.00835326,1.20281 kka2_1:8_V242G,kka2_1:8_242,Kka2,kka2_1:8,P00552,1.20297,NO,242,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-2.687,-3.538,0.851,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.100394,0.0102575,1.20297 kka2_1:8_V242G,kka2_1:8_242,Kka2,kka2_1:8,P00552,1.20297,NO,242,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-2.687,-3.538,0.851,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.100394,0.0102575,1.20297 kka2_1:2_I2W,kka2_1:2_2,Kka2,kka2_1:2,P00552,1.20302,NO,2,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.787,-5.093,3.306,,,,,,,5.773,,71.59,HHA,-1.92433,0.295029,0.00246644,1.20302 kka2_1:8_G74N,kka2_1:8_74,Kka2,kka2_1:8,P00552,1.20304,NO,74,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.18,-2.406,1.226,,0.621,T,l,0.29,0.2,2.014,,64.39,POH,-1.91667,0.100394,0.00587035,1.20304 kka2_1:8_G74N,kka2_1:8_74,Kka2,kka2_1:8,P00552,1.20304,NO,74,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.18,-2.406,1.226,,0.621,T,l,0.29,0.2,2.014,,64.39,POH,-1.91667,0.100394,0.00587035,1.20304 kka2_1:8_L19I,kka2_1:8_19,Kka2,kka2_1:8,P00552,1.2032,NO,19,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.254,-2.338,1.084,,0.08,T,A,1.59,-0.26,2.044,,65.53,BHH,-2.221,0.100394,0.00620703,1.2032 kka2_1:8_L19I,kka2_1:8_19,Kka2,kka2_1:8,P00552,1.2032,NO,19,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.254,-2.338,1.084,,0.08,T,A,1.59,-0.26,2.044,,65.53,BHH,-2.221,0.100394,0.00620703,1.2032 kka2_1:2_E230C,kka2_1:2_230,Kka2,kka2_1:2,P00552,1.20327,NO,230,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.672,-3.614,0.942,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.295029,0.00920051,1.20327 kka2_1:2_Q163D,kka2_1:2_163,Kka2,kka2_1:2,P00552,1.20327,NO,163,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.162,-3.807,1.645,,0.58,T,B,0.64,1.85,3.888,,64.02,BPO,-1.78333,0.295029,0.00719507,1.20327 kka2_1:4_D227E,kka2_1:4_227,Kka2,kka2_1:4,P00552,1.20328,NO,227,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.758,-3.138,1.38,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.168804,0.00745029,1.20328 kka2_1:2_A41G,kka2_1:2_41,Kka2,kka2_1:2,P00552,1.20329,NO,41,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.879,-2.32,0.441,,0.184,.,B,0.46,-0.96,24.451,24.451,64.39,PHP,-2.477,0.295029,0.00543332,1.20329 kka2_1:8_V46D,kka2_1:8_46,Kka2,kka2_1:8,P00552,1.20333,NO,46,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-2.62,-2.475,-0.145,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.100394,0.00631301,1.20333 kka2_1:8_V46D,kka2_1:8_46,Kka2,kka2_1:8,P00552,1.20333,NO,46,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-2.62,-2.475,-0.145,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.100394,0.00631301,1.20333 kka2_1:8_W15F,kka2_1:8_15,Kka2,kka2_1:8,P00552,1.2034,NO,15,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-1.392,-2.518,1.126,,0.01,G,A,1.51,0.15,0.827,,52.27,HHH,-2.10533,0.100394,0.00585505,1.2034 kka2_1:8_W15F,kka2_1:8_15,Kka2,kka2_1:8,P00552,1.2034,NO,15,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-1.392,-2.518,1.126,,0.01,G,A,1.51,0.15,0.827,,52.27,HHH,-2.10533,0.100394,0.00585505,1.2034 beta-lactamase_0_M209C,beta-lactamase_0_209,TEM-1,beta-lactamase_0,P62593,1.2035,NO,209,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.442,-4.758,3.316,,,H,A,0.55,-0.97,3.876,,64.69,HHA,-1.52633,0.0500837,0.00625021,1.2035 kka2_1:4_R44H,kka2_1:4_44,Kka2,kka2_1:4,P00552,1.20356,NO,44,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.062,-3.488,1.426,,0.487,S,B,1.2,-0.35,5.71,,71.59,OBO,-1.80767,0.168804,0.00745043,1.20356 kka2_1:8_A150M,kka2_1:8_150,Kka2,kka2_1:8,P00552,1.20357,NO,150,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.949,-4.623,3.674,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.100394,0.0045009,1.20357 kka2_1:8_A150M,kka2_1:8_150,Kka2,kka2_1:8,P00552,1.20357,NO,150,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.949,-4.623,3.674,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.100394,0.0045009,1.20357 kka2_1:8_S40M,kka2_1:8_40,Kka2,kka2_1:8,P00552,1.20378,NO,40,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.645,-4.831,2.186,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.100394,0.00693477,1.20378 kka2_1:8_S40M,kka2_1:8_40,Kka2,kka2_1:8,P00552,1.20378,NO,40,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.645,-4.831,2.186,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.100394,0.00693477,1.20378 kka2_1:2_C209V,kka2_1:2_209,Kka2,kka2_1:2,P00552,1.20386,NO,209,C,V,CV,Special,Hydrophobic,5.07,5.60847,0.538465,192,121,117,-4,108.5,140,31.5,-0.906,-3.299,2.393,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.295029,0.00260862,1.20386 kka2_1:8_V242N,kka2_1:8_242,Kka2,kka2_1:8,P00552,1.20401,NO,242,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-2.687,-3.122,0.435,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.100394,0.0102575,1.20401 kka2_1:8_V242N,kka2_1:8_242,Kka2,kka2_1:8,P00552,1.20401,NO,242,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-2.687,-3.122,0.435,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.100394,0.0102575,1.20401 kka2_1:8_E142A,kka2_1:8_142,Kka2,kka2_1:8,P00552,1.20403,NO,142,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.221,-1.748,-0.473,,0.471,H,A,1.04,0.85,2.655,,65.53,HAB,-2.08033,0.100394,0.00748883,1.20403 kka2_1:8_E142A,kka2_1:8_142,Kka2,kka2_1:8,P00552,1.20403,NO,142,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.221,-1.748,-0.473,,0.471,H,A,1.04,0.85,2.655,,65.53,HAB,-2.08033,0.100394,0.00748883,1.20403 kka2_1:8_L152I,kka2_1:8_152,Kka2,kka2_1:8,P00552,1.20406,NO,152,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.521,-2.522,1.001,,0.547,.,A,0.55,1.36,1.442,,63.64,OHH,-1.162,0.100394,0.00674868,1.20406 kka2_1:8_L152I,kka2_1:8_152,Kka2,kka2_1:8,P00552,1.20406,NO,152,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.521,-2.522,1.001,,0.547,.,A,0.55,1.36,1.442,,63.64,OHH,-1.162,0.100394,0.00674868,1.20406 kka2_1:8_A137C,kka2_1:8_137,Kka2,kka2_1:8,P00552,1.20415,NO,137,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.156,-4.817,2.661,,0.029,H,A,1.04,0.34,2.886,,63.26,PHB,-2.559,0.100394,0.00515054,1.20415 kka2_1:8_A137C,kka2_1:8_137,Kka2,kka2_1:8,P00552,1.20415,NO,137,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.156,-4.817,2.661,,0.029,H,A,1.04,0.34,2.886,,63.26,PHB,-2.559,0.100394,0.00515054,1.20415 kka2_1:8_I254A,kka2_1:8_254,Kka2,kka2_1:8,P00552,1.20416,NO,254,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.933,-2.534,0.601,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.100394,0.0132375,1.20416 kka2_1:8_I254A,kka2_1:8_254,Kka2,kka2_1:8,P00552,1.20416,NO,254,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.933,-2.534,0.601,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.100394,0.0132375,1.20416 kka2_1:2_T73M,kka2_1:2_73,Kka2,kka2_1:2,P00552,1.2042,NO,73,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.51,-3.216,0.706,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.295029,0.00628605,1.2042 kka2_1:8_A137F,kka2_1:8_137,Kka2,kka2_1:8,P00552,1.20424,NO,137,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.156,-3.905,1.749,,0.029,H,A,1.04,0.34,2.886,,63.26,PHB,-2.559,0.100394,0.00515054,1.20424 kka2_1:8_A137F,kka2_1:8_137,Kka2,kka2_1:8,P00552,1.20424,NO,137,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.156,-3.905,1.749,,0.029,H,A,1.04,0.34,2.886,,63.26,PHB,-2.559,0.100394,0.00515054,1.20424 kka2_1:8_D180F,kka2_1:8_180,Kka2,kka2_1:8,P00552,1.20425,NO,180,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.416,-4.402,1.986,,1.03,S,a,0.75,1.5,14.668,14.668,71.59,OAO,-2.02933,0.100394,0.00756412,1.20425 kka2_1:8_D180F,kka2_1:8_180,Kka2,kka2_1:8,P00552,1.20425,NO,180,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.416,-4.402,1.986,,1.03,S,a,0.75,1.5,14.668,14.668,71.59,OAO,-2.02933,0.100394,0.00756412,1.20425 kka2_1:4_E235D,kka2_1:4_235,Kka2,kka2_1:4,P00552,1.20432,NO,235,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.955,-2.602,0.647,,0.631,H,A,1.04,0.12,23.175,23.175,65.53,OAH,-2.07267,0.168804,0.0102806,1.20432 beta-lactamase_0_I206W,beta-lactamase_0_206,TEM-1,beta-lactamase_0,P62593,1.20433,NO,206,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-2.429,-5.397,2.968,,0.173,H,A,0.48,-0.34,3.411,,77.62,HHA,-1.805,0.0500837,0.00528934,1.20433 kka2_1:8_E160Q,kka2_1:8_160,Kka2,kka2_1:8,P00552,1.20443,NO,160,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.683,-3.734,2.051,,0.989,G,A,1.04,2.28,2.164,,71.59,AAA,-1.36133,0.100394,0.00935762,1.20443 kka2_1:8_E160Q,kka2_1:8_160,Kka2,kka2_1:8,P00552,1.20443,NO,160,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.683,-3.734,2.051,,0.989,G,A,1.04,2.28,2.164,,71.59,AAA,-1.36133,0.100394,0.00935762,1.20443 kka2_1:4_E160H,kka2_1:4_160,Kka2,kka2_1:4,P00552,1.20447,NO,160,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.683,-4.581,2.898,,0.989,G,A,1.04,2.28,2.531,,71.59,AAA,-1.36133,0.168804,0.00935762,1.20447 kka2_1:2_V80C,kka2_1:2_80,Kka2,kka2_1:2,P00552,1.20484,NO,80,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.144,-4.756,3.612,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.295029,0.00488211,1.20484 kka2_1:4_P98G,kka2_1:4_98,Kka2,kka2_1:4,P00552,1.20489,NO,98,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.526,-3.498,1.972,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.168804,0.00622754,1.20489 kka2_1:4_G21A,kka2_1:4_21,Kka2,kka2_1:4,P00552,1.20504,NO,21,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.368,-2.331,0.963,,0.586,T,l,0.75,-0.75,3.075,,71.59,HOH,-2.10167,0.168804,0.00709648,1.20504 kka2_1:4_S40D,kka2_1:4_40,Kka2,kka2_1:4,P00552,1.2051,NO,40,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.645,-2.229,-0.416,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.168804,0.00693477,1.2051 beta-lactamase_0_K190E,beta-lactamase_0_190,TEM-1,beta-lactamase_0,P62593,1.20512,NO,190,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.994,-3.44,1.446,,0.371,H,A,2.34,0.16,16.606,16.606,77.62,BBH,-1.64167,0.0500837,0.00574527,1.20512 beta-lactamase_0_R92K,beta-lactamase_0_92,TEM-1,beta-lactamase_0,P62593,1.20513,NO,92,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.718,-2.258,0.54,,0.479,E,B,1.2,1.36,2.331,,65.38,BBH,-1.50367,0.0500837,0.00429626,1.20513 beta-lactamase_0_E108V,beta-lactamase_0_108,TEM-1,beta-lactamase_0,P62593,1.20519,NO,108,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.46,-3.706,2.246,,0.572,G,A,1.04,1.87,8.602,8.602,72.73,PAB,-1.437,0.0500837,0.00413372,1.20519 kka2_1:4_A166P,kka2_1:4_166,Kka2,kka2_1:4,P00552,1.2052,NO,166,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.407,-2.34,-0.067,,0.534,.,B,0.46,1.03,,,71.59,HHO,-2.421,0.168804,0.00799912,1.2052 kka2_1:2_E142A,kka2_1:2_142,Kka2,kka2_1:2,P00552,1.20527,NO,142,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.221,-1.748,-0.473,,0.471,H,A,1.52,0.85,3.693,,65.53,HAB,-2.08033,0.295029,0.00748883,1.20527 kka2_1:4_P12C,kka2_1:4_12,Kka2,kka2_1:4,P00552,1.2053,NO,12,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.853,-4.98,4.127,,,,B,0.52,1.25,0.843,,48.11,POH,-1.80767,0.168804,0.00500011,1.2053 kka2_1:8_E199T,kka2_1:8_199,Kka2,kka2_1:8,P00552,1.20531,NO,199,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.234,-2.695,0.461,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.100394,0.00854122,1.20531 kka2_1:8_E199T,kka2_1:8_199,Kka2,kka2_1:8,P00552,1.20531,NO,199,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.234,-2.695,0.461,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.100394,0.00854122,1.20531 kka2_1:4_A56R,kka2_1:4_56,Kka2,kka2_1:4,P00552,1.20536,NO,56,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.083,-3.254,1.171,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.168804,0.00717715,1.20536 kka2_1:8_E231N,kka2_1:8_231,Kka2,kka2_1:8,P00552,1.20536,NO,231,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.002,-1.271,-0.731,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.100394,0.00732383,1.20536 kka2_1:8_E231N,kka2_1:8_231,Kka2,kka2_1:8,P00552,1.20536,NO,231,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.002,-1.271,-0.731,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.100394,0.00732383,1.20536 kka2_1:8_A172D,kka2_1:8_172,Kka2,kka2_1:8,P00552,1.20539,NO,172,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.757,-2.549,0.792,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.100394,0.0079265,1.20539 kka2_1:8_A172D,kka2_1:8_172,Kka2,kka2_1:8,P00552,1.20539,NO,172,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.757,-2.549,0.792,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.100394,0.0079265,1.20539 kka2_1:2_Q27T,kka2_1:2_27,Kka2,kka2_1:2,P00552,1.20549,NO,27,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-1.659,-3.598,1.939,,0.608,.,A,0.64,0.71,0.521,,65.53,PPP,-1.90733,0.295029,0.00595365,1.20549 kka2_1:4_R143T,kka2_1:4_143,Kka2,kka2_1:4,P00552,1.2055,NO,143,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.525,-2.557,0.032,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.168804,0.00662247,1.2055 beta-lactamase_0_A84K,beta-lactamase_0_84,TEM-1,beta-lactamase_0,P62593,1.20557,NO,84,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.651,-2.484,0.833,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.0500837,0.00503822,1.20557 kka2_1:4_A191C,kka2_1:4_191,Kka2,kka2_1:4,P00552,1.20559,NO,191,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.831,-4.548,3.717,,,.,b,0.46,-0.94,2.046,,50,AHO,-0.868667,0.168804,0.00338807,1.20559 kka2_1:4_R239A,kka2_1:4_239,Kka2,kka2_1:4,P00552,1.20567,NO,239,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.949,-2.185,-0.764,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.168804,0.00835326,1.20567 beta-lactamase_0_H110V,beta-lactamase_0_110,TEM-1,beta-lactamase_0,P62593,1.2057,NO,110,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-1.706,-3.735,2.029,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.0500837,0.00441499,1.2057 kka2_1:8_R173W,kka2_1:8_173,Kka2,kka2_1:8,P00552,1.20579,NO,173,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.407,-3.224,0.817,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.100394,0.00784999,1.20579 kka2_1:8_R173W,kka2_1:8_173,Kka2,kka2_1:8,P00552,1.20579,NO,173,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.407,-3.224,0.817,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.100394,0.00784999,1.20579 kka2_1:2_L47M,kka2_1:2_47,Kka2,kka2_1:2,P00552,1.20585,NO,47,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.265,-4.186,2.921,,0.139,E,B,0.55,-0.86,2.369,,63.26,HHH,-1.77933,0.295029,0.00509386,1.20585 kka2_1:4_F20V,kka2_1:4_20,Kka2,kka2_1:4,P00552,1.20597,NO,20,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-3.354,-2.808,-0.546,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.168804,0.00701744,1.20597 kka2_1:2_A25F,kka2_1:2_25,Kka2,kka2_1:2,P00552,1.20604,NO,25,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.496,-4.408,1.912,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.295029,0.00595636,1.20604 kka2_1:8_M178T,kka2_1:8_178,Kka2,kka2_1:8,P00552,1.20604,NO,178,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-3.206,-3.644,0.438,,0.554,,b,1.59,0.68,13.268,13.268,71.59,BHO,-2.154,0.100394,0.00717253,1.20604 kka2_1:8_M178T,kka2_1:8_178,Kka2,kka2_1:8,P00552,1.20604,NO,178,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-3.206,-3.644,0.438,,0.554,,b,1.59,0.68,13.268,13.268,71.59,BHO,-2.154,0.100394,0.00717253,1.20604 beta-lactamase_0_S80I,beta-lactamase_0_80,TEM-1,beta-lactamase_0,P62593,1.20607,NO,80,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.029,-3.787,1.758,,0.192,H,A,0.27,0.46,12.403,12.403,77.62,HPB,-1.44567,0.0500837,0.00565569,1.20607 kka2_1:2_H8N,kka2_1:2_8,Kka2,kka2_1:2,P00552,1.20609,NO,8,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-2.759,-3.586,0.827,,,,,,,,,71.59,HBH,-2.25467,0.295029,0.00256422,1.20609 kka2_1:8_A41D,kka2_1:8_41,Kka2,kka2_1:8,P00552,1.2061,NO,41,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.879,-3.164,1.285,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.100394,0.00543332,1.2061 kka2_1:8_A41D,kka2_1:8_41,Kka2,kka2_1:8,P00552,1.2061,NO,41,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.879,-3.164,1.285,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.100394,0.00543332,1.2061 kka2_1:8_I254G,kka2_1:8_254,Kka2,kka2_1:8,P00552,1.20611,NO,254,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.933,-3.809,1.876,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.100394,0.0132375,1.20611 kka2_1:8_I254G,kka2_1:8_254,Kka2,kka2_1:8,P00552,1.20611,NO,254,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.933,-3.809,1.876,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.100394,0.0132375,1.20611 kka2_1:8_S204A,kka2_1:8_204,Kka2,kka2_1:8,P00552,1.20615,NO,204,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.353,-1.861,0.508,,0.144,E,A,0.27,-1.2,0.368,,65.53,HPO,-0.953333,0.100394,0.00881794,1.20615 kka2_1:8_S204A,kka2_1:8_204,Kka2,kka2_1:8,P00552,1.20615,NO,204,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.353,-1.861,0.508,,0.144,E,A,0.27,-1.2,0.368,,65.53,HPO,-0.953333,0.100394,0.00881794,1.20615 kka2_1:8_Q26T,kka2_1:8_26,Kka2,kka2_1:8,P00552,1.20616,NO,26,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.18,-3.677,1.497,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.100394,0.00708962,1.20616 kka2_1:8_Q26T,kka2_1:8_26,Kka2,kka2_1:8,P00552,1.20616,NO,26,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.18,-3.677,1.497,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.100394,0.00708962,1.20616 kka2_1:8_I2W,kka2_1:8_2,Kka2,kka2_1:8,P00552,1.20617,NO,2,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.787,-5.093,3.306,,,,,,,,,71.59,HHA,-1.92433,0.100394,0.00246644,1.20617 kka2_1:8_I2W,kka2_1:8_2,Kka2,kka2_1:8,P00552,1.20617,NO,2,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.787,-5.093,3.306,,,,,,,,,71.59,HHA,-1.92433,0.100394,0.00246644,1.20617 kka2_1:8_S11R,kka2_1:8_11,Kka2,kka2_1:8,P00552,1.20618,NO,11,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.322,-3.926,1.604,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.100394,0.00381691,1.20618 kka2_1:8_S11R,kka2_1:8_11,Kka2,kka2_1:8,P00552,1.20618,NO,11,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.322,-3.926,1.604,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.100394,0.00381691,1.20618 kka2_1:4_D154V,kka2_1:4_154,Kka2,kka2_1:4,P00552,1.20623,NO,154,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-0.876,-3.815,2.939,,0.457,,b,0.29,1.48,15.641,15.641,52.65,HAP,-1.52467,0.168804,0.00292633,1.20623 kka2_1:2_D33R,kka2_1:2_33,Kka2,kka2_1:2,P00552,1.20625,NO,33,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.186,-2.468,0.282,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.295029,0.00633568,1.20625 kka2_1:4_Q100S,kka2_1:4_100,Kka2,kka2_1:4,P00552,1.20641,NO,100,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.77,-2.33,-0.44,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.168804,0.0066405,1.20641 kka2_1:4_R44C,kka2_1:4_44,Kka2,kka2_1:4,P00552,1.20641,NO,44,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.062,-5.189,3.127,,0.487,S,B,1.2,-0.35,5.71,,71.59,OBO,-1.80767,0.168804,0.00745043,1.20641 kka2_1:8_E149Y,kka2_1:8_149,Kka2,kka2_1:8,P00552,1.20645,NO,149,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.994,-4.359,2.365,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.100394,0.00803343,1.20645 kka2_1:8_E149Y,kka2_1:8_149,Kka2,kka2_1:8,P00552,1.20645,NO,149,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.994,-4.359,2.365,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.100394,0.00803343,1.20645 kka2_1:8_S114E,kka2_1:8_114,Kka2,kka2_1:8,P00552,1.20646,NO,114,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.527,-2.055,-0.472,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.100394,0.00705262,1.20646 kka2_1:8_S114E,kka2_1:8_114,Kka2,kka2_1:8,P00552,1.20646,NO,114,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.527,-2.055,-0.472,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.100394,0.00705262,1.20646 kka2_1:2_R239K,kka2_1:2_239,Kka2,kka2_1:2,P00552,1.20647,NO,239,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.949,-3.654,0.705,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.295029,0.00835326,1.20647 kka2_1:8_V46I,kka2_1:8_46,Kka2,kka2_1:8,P00552,1.20658,NO,46,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-2.62,-3.923,1.303,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.100394,0.00631301,1.20658 kka2_1:8_V46I,kka2_1:8_46,Kka2,kka2_1:8,P00552,1.20658,NO,46,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-2.62,-3.923,1.303,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.100394,0.00631301,1.20658 kka2_1:2_Q100T,kka2_1:2_100,Kka2,kka2_1:2,P00552,1.20669,NO,100,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.77,-2.757,-0.013,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.295029,0.0066405,1.20669 kka2_1:8_F256Y,kka2_1:8_256,Kka2,kka2_1:8,P00552,1.20677,NO,256,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.49,-1.474,-0.016,,,H,A,1.62,-0.78,1.713,,53.03,HHH,-1.423,0.100394,0.0132841,1.20677 kka2_1:8_F256Y,kka2_1:8_256,Kka2,kka2_1:8,P00552,1.20677,NO,256,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.49,-1.474,-0.016,,,H,A,1.62,-0.78,1.713,,53.03,HHH,-1.423,0.100394,0.0132841,1.20677 kka2_1:8_G181K,kka2_1:8_181,Kka2,kka2_1:8,P00552,1.20677,NO,181,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-2.698,-3.658,0.96,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.100394,0.00728319,1.20677 kka2_1:8_G181K,kka2_1:8_181,Kka2,kka2_1:8,P00552,1.20677,NO,181,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-2.698,-3.658,0.96,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.100394,0.00728319,1.20677 beta-lactamase_0_L188H,beta-lactamase_0_188,TEM-1,beta-lactamase_0,P62593,1.20687,NO,188,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.166,-4.872,3.706,,,H,A,0.55,-0.3,2.739,,60.14,PHB,-1.47033,0.0500837,0.00295687,1.20687 kka2_1:8_T146A,kka2_1:8_146,Kka2,kka2_1:8,P00552,1.2069,NO,146,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.978,-1.627,-1.351,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.100394,0.00606474,1.2069 kka2_1:8_T146A,kka2_1:8_146,Kka2,kka2_1:8,P00552,1.2069,NO,146,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.978,-1.627,-1.351,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.100394,0.00606474,1.2069 kka2_1:2_A41H,kka2_1:2_41,Kka2,kka2_1:2,P00552,1.20696,NO,41,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.879,-3.045,1.166,,0.184,.,B,0.46,-0.96,24.451,24.451,64.39,PHP,-2.477,0.295029,0.00543332,1.20696 kka2_1:8_A41M,kka2_1:8_41,Kka2,kka2_1:8,P00552,1.207,NO,41,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.879,-3.613,1.734,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.100394,0.00543332,1.207 kka2_1:8_A41M,kka2_1:8_41,Kka2,kka2_1:8,P00552,1.207,NO,41,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.879,-3.613,1.734,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.100394,0.00543332,1.207 beta-lactamase_0_A215H,beta-lactamase_0_215,TEM-1,beta-lactamase_0,P62593,1.20702,NO,215,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.503,-4.741,3.238,,,,a,0.46,-0.93,0.494,,74.48,HHO,-1.42633,0.0500837,0.00544007,1.20702 kka2_1:4_Q155R,kka2_1:4_155,Kka2,kka2_1:4,P00552,1.20703,NO,155,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.606,-3.728,1.122,,0.525,T,A,0.64,1.49,1.592,,63.64,APA,-1.726,0.168804,0.00641853,1.20703 kka2_1:4_W24F,kka2_1:4_24,Kka2,kka2_1:4,P00552,1.20705,NO,24,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-1.779,-2.325,0.546,,0.477,E,B,1.51,-0.21,2.666,,56.06,AHH,-2.24467,0.168804,0.00631564,1.20705 kka2_1:8_V16H,kka2_1:8_16,Kka2,kka2_1:8,P00552,1.20715,NO,16,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-3.087,-3.512,0.425,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.100394,0.00694011,1.20715 kka2_1:8_V16H,kka2_1:8_16,Kka2,kka2_1:8,P00552,1.20715,NO,16,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-3.087,-3.512,0.425,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.100394,0.00694011,1.20715 beta-lactamase_0_S201A,beta-lactamase_0_201,TEM-1,beta-lactamase_0,P62593,1.20718,NO,201,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.183,-2.127,0.944,,0.064,H,A,0.27,-0.07,3.54,,64.69,HPB,-1.451,0.0500837,0.00198815,1.20718 kka2_1:4_I2G,kka2_1:4_2,Kka2,kka2_1:4,P00552,1.20756,NO,2,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.787,-3.438,1.651,,,,,,,,,71.59,HHA,-1.92433,0.168804,0.00246644,1.20756 kka2_1:8_S251I,kka2_1:8_251,Kka2,kka2_1:8,P00552,1.20756,NO,251,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.636,-4.095,1.459,,0.712,H,A,0.27,-0.25,,,71.59,APP,-2.09367,0.100394,0.0138916,1.20756 kka2_1:8_S251I,kka2_1:8_251,Kka2,kka2_1:8,P00552,1.20756,NO,251,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.636,-4.095,1.459,,0.712,H,A,0.27,-0.25,,,71.59,APP,-2.09367,0.100394,0.0138916,1.20756 beta-lactamase_0_L219Y,beta-lactamase_0_219,TEM-1,beta-lactamase_0,P62593,1.2077,NO,219,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.313,-3.958,2.645,,,I,A,0.55,-0.51,6.513,6.513,74.48,HHB,-1.21533,0.0500837,0.00664345,1.2077 beta-lactamase_0_G253Y,beta-lactamase_0_253,TEM-1,beta-lactamase_0,P62593,1.20791,NO,253,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-2.253,,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.0500837,0.00786358,1.20791 kka2_1:8_T73I,kka2_1:8_73,Kka2,kka2_1:8,P00552,1.208,NO,73,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.51,-3.77,1.26,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.100394,0.00628605,1.208 kka2_1:8_T73I,kka2_1:8_73,Kka2,kka2_1:8,P00552,1.208,NO,73,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.51,-3.77,1.26,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.100394,0.00628605,1.208 beta-lactamase_0_D99S,beta-lactamase_0_99,TEM-1,beta-lactamase_0,P62593,1.20803,NO,99,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.191,-3.286,2.095,,0.402,G,A,0.75,0.36,0.374,,64.69,PAH,-1.794,0.0500837,0.00305446,1.20803 kka2_1:4_G181E,kka2_1:4_181,Kka2,kka2_1:4,P00552,1.20804,NO,181,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-2.698,-2.628,-0.07,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.168804,0.00728319,1.20804 kka2_1:4_P167M,kka2_1:4_167,Kka2,kka2_1:4,P00552,1.20808,NO,167,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-2.403,-4.574,2.171,,0.18,H,A,0.52,0.75,3.6,,64.39,HOH,-2.26633,0.168804,0.00543203,1.20808 kka2_1:4_A9Y,kka2_1:4_9,Kka2,kka2_1:4,P00552,1.20811,NO,9,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.079,-4.09,2.011,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.168804,0.00273264,1.20811 kka2_1:4_E230S,kka2_1:4_230,Kka2,kka2_1:4,P00552,1.20811,NO,230,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.672,-2.395,-0.277,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.168804,0.00920051,1.20811 kka2_1:2_G181T,kka2_1:2_181,Kka2,kka2_1:2,P00552,1.2082,NO,181,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-2.698,-2.358,-0.34,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.295029,0.00728319,1.2082 kka2_1:8_A14T,kka2_1:8_14,Kka2,kka2_1:8,P00552,1.20823,NO,14,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.837,-2.286,0.449,,0.728,G,A,0.46,0.7,,,71.59,HHH,-1.82567,0.100394,0.00706614,1.20823 kka2_1:8_A14T,kka2_1:8_14,Kka2,kka2_1:8,P00552,1.20823,NO,14,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.837,-2.286,0.449,,0.728,G,A,0.46,0.7,,,71.59,HHH,-1.82567,0.100394,0.00706614,1.20823 kka2_1:8_A79R,kka2_1:8_79,Kka2,kka2_1:8,P00552,1.20833,NO,79,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.368,-2.341,-0.027,,0.563,.,B,0.46,-0.43,,,71.59,HHH,-1.752,0.100394,0.00664821,1.20833 kka2_1:8_A79R,kka2_1:8_79,Kka2,kka2_1:8,P00552,1.20833,NO,79,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.368,-2.341,-0.027,,0.563,.,B,0.46,-0.43,,,71.59,HHH,-1.752,0.100394,0.00664821,1.20833 kka2_1:4_P76G,kka2_1:4_76,Kka2,kka2_1:4,P00552,1.20841,NO,76,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.449,-3.458,2.009,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.168804,0.00625685,1.20841 gb1_A250F,gb1_250,gb1,gb1,P06654,1.20842,NO,250,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.713,-4.067,2.354,,,,,,,3.465,,45.54,HHP,-1.74867,0.177985,0.00332003,1.20842 PSD95pdz3_P311Y,PSD95pdz3_311,PSD95pdz3,PSD95pdz3,P31016,1.20847,NO,311,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.236,-4.069,2.833,5.76649,,,,,14.78,,,,OOB,-1.409,0.0758425,0.0030796,1.20847 kka2_1:4_L223I,kka2_1:4_223,Kka2,kka2_1:4,P00552,1.20849,NO,223,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.861,-2.071,1.21,,,H,A,1.59,-1.24,1.268,,50,HHH,-0.854333,0.168804,0.00253574,1.20849 kka2_1:2_G6H,kka2_1:2_6,Kka2,kka2_1:2,P00552,1.20852,NO,6,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.685,-4.557,2.872,,,,,,,,,71.59,AOH,-1.639,0.295029,0.00204693,1.20852 kka2_1:4_T72H,kka2_1:4_72,Kka2,kka2_1:4,P00552,1.20853,NO,72,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.38,-4.753,2.373,,0.784,H,A,0.82,0.29,6.463,,65.53,HPP,-2.238,0.168804,0.00750756,1.20853 kka2_1:8_Q100I,kka2_1:8_100,Kka2,kka2_1:8,P00552,1.20856,NO,100,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.77,-3.068,0.298,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.100394,0.0066405,1.20856 kka2_1:8_Q100I,kka2_1:8_100,Kka2,kka2_1:8,P00552,1.20856,NO,100,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.77,-3.068,0.298,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.100394,0.0066405,1.20856 kka2_1:8_Q26R,kka2_1:8_26,Kka2,kka2_1:8,P00552,1.20856,NO,26,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.18,-1.791,-0.389,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.100394,0.00708962,1.20856 kka2_1:8_Q26R,kka2_1:8_26,Kka2,kka2_1:8,P00552,1.20856,NO,26,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.18,-1.791,-0.389,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.100394,0.00708962,1.20856 kka2_1:8_M116L,kka2_1:8_116,Kka2,kka2_1:8,P00552,1.20867,NO,116,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-2.482,-1.52,-0.962,,,H,A,1.59,-0.88,4.659,,71.59,HHH,-1.63867,0.100394,0.00745147,1.20867 kka2_1:8_M116L,kka2_1:8_116,Kka2,kka2_1:8,P00552,1.20867,NO,116,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-2.482,-1.52,-0.962,,,H,A,1.59,-0.88,4.659,,71.59,HHH,-1.63867,0.100394,0.00745147,1.20867 beta-lactamase_0_I285L,beta-lactamase_0_285,TEM-1,beta-lactamase_0,P62593,1.20879,NO,285,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.0500837,0.101555,1.20879 beta-lactamase_0_K190R,beta-lactamase_0_190,TEM-1,beta-lactamase_0,P62593,1.20885,NO,190,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.994,-2.302,0.308,,0.371,H,A,2.34,0.16,16.606,16.606,77.62,BBH,-1.64167,0.0500837,0.00574527,1.20885 kka2_1:4_L57H,kka2_1:4_57,Kka2,kka2_1:4,P00552,1.20893,NO,57,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.898,-2.613,0.715,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.168804,0.00723769,1.20893 kka2_1:4_R143D,kka2_1:4_143,Kka2,kka2_1:4,P00552,1.20896,NO,143,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.525,-2.588,0.063,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.168804,0.00662247,1.20896 kka2_1:8_E235I,kka2_1:8_235,Kka2,kka2_1:8,P00552,1.20897,NO,235,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.955,-4.019,2.064,,0.631,H,A,1.52,0.12,,,65.53,OAH,-2.07267,0.100394,0.0102806,1.20897 kka2_1:8_E235I,kka2_1:8_235,Kka2,kka2_1:8,P00552,1.20897,NO,235,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.955,-4.019,2.064,,0.631,H,A,1.52,0.12,,,65.53,OAH,-2.07267,0.100394,0.0102806,1.20897 kka2_1:4_V153W,kka2_1:4_153,Kka2,kka2_1:4,P00552,1.20898,NO,153,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.092,-5.429,4.337,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.168804,0.00501119,1.20898 kka2_1:8_L158R,kka2_1:8_158,Kka2,kka2_1:8,P00552,1.20908,NO,158,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.947,-4.189,2.242,,0.095,.,B,0.55,0.77,1.607,,63.64,AHA,-1.25333,0.100394,0.00529068,1.20908 kka2_1:8_L158R,kka2_1:8_158,Kka2,kka2_1:8,P00552,1.20908,NO,158,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.947,-4.189,2.242,,0.095,.,B,0.55,0.77,1.607,,63.64,AHA,-1.25333,0.100394,0.00529068,1.20908 kka2_1:2_L7Q,kka2_1:2_7,Kka2,kka2_1:2,P00552,1.20912,NO,7,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.926,-3.782,1.856,,,,,,,3.012,,71.59,OHB,-2.12333,0.295029,0.00269456,1.20912 kka2_1:2_Q163T,kka2_1:2_163,Kka2,kka2_1:2,P00552,1.20923,NO,163,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.162,-2.589,0.427,,0.58,T,B,0.64,1.85,3.888,,64.02,BPO,-1.78333,0.295029,0.00719507,1.20923 kka2_1:4_L165R,kka2_1:4_165,Kka2,kka2_1:4,P00552,1.20923,NO,165,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-2.453,-2.067,-0.386,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.168804,0.00801161,1.20923 kka2_1:4_A13W,kka2_1:4_13,Kka2,kka2_1:4,P00552,1.20925,NO,13,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.248,-3.869,1.621,,0.689,G,A,0.46,0.99,,,92.05,OHH,-1.646,0.168804,0.00784241,1.20925 kka2_1:2_P128V,kka2_1:2_128,Kka2,kka2_1:2,P00552,1.20933,NO,128,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.922,-2.023,0.101,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.295029,0.00774689,1.20933 kka2_1:4_T28Y,kka2_1:4_28,Kka2,kka2_1:4,P00552,1.20936,NO,28,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.883,-4.4,2.517,,0.353,S,B,0.82,2.02,4.415,,63.64,PPH,-1.74467,0.168804,0.00743084,1.20936 kka2_1:4_V186I,kka2_1:4_186,Kka2,kka2_1:4,P00552,1.20936,NO,186,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.011,-2.092,1.081,,,E,B,0.44,-0.61,0.679,,45.83,HHP,-1.10967,0.168804,0.00409703,1.20936 kka2_1:8_R143Q,kka2_1:8_143,Kka2,kka2_1:8,P00552,1.2094,NO,143,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.525,-3.295,0.77,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.100394,0.00662247,1.2094 kka2_1:8_R143Q,kka2_1:8_143,Kka2,kka2_1:8,P00552,1.2094,NO,143,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.525,-3.295,0.77,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.100394,0.00662247,1.2094 kka2_1:4_A9R,kka2_1:4_9,Kka2,kka2_1:4,P00552,1.20948,NO,9,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.079,-3.835,1.756,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.168804,0.00273264,1.20948 beta-lactamase_0_F149C,beta-lactamase_0_149,TEM-1,beta-lactamase_0,P62593,1.20951,NO,149,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.299,-4.94,3.641,,0.195,H,A,0.58,0.11,3.518,,63.99,HHH,-1.46067,0.0500837,0.00418462,1.20951 kka2_1:8_A176L,kka2_1:8_176,Kka2,kka2_1:8,P00552,1.2096,NO,176,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.621,-3.555,1.934,,0.806,H,A,0.46,-0.03,18.904,18.904,65.53,BHB,-2.26667,0.100394,0.0083587,1.2096 kka2_1:8_A176L,kka2_1:8_176,Kka2,kka2_1:8,P00552,1.2096,NO,176,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.621,-3.555,1.934,,0.806,H,A,0.46,-0.03,18.904,18.904,65.53,BHB,-2.26667,0.100394,0.0083587,1.2096 kka2_1:8_M178R,kka2_1:8_178,Kka2,kka2_1:8,P00552,1.20965,NO,178,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-3.206,-1.763,-1.443,,0.554,,b,1.59,0.68,13.268,13.268,71.59,BHO,-2.154,0.100394,0.00717253,1.20965 kka2_1:8_M178R,kka2_1:8_178,Kka2,kka2_1:8,P00552,1.20965,NO,178,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-3.206,-1.763,-1.443,,0.554,,b,1.59,0.68,13.268,13.268,71.59,BHO,-2.154,0.100394,0.00717253,1.20965 beta-lactamase_0_G243D,beta-lactamase_0_243,TEM-1,beta-lactamase_0,P62593,1.20978,NO,243,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.0500837,0.00464034,1.20978 kka2_1:4_E149A,kka2_1:4_149,Kka2,kka2_1:4,P00552,1.20987,NO,149,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.994,-2.44,0.446,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.168804,0.00803343,1.20987 beta-lactamase_0_D99A,beta-lactamase_0_99,TEM-1,beta-lactamase_0,P62593,1.20994,NO,99,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.191,-2.613,1.422,,0.402,G,A,0.75,0.36,0.374,,64.69,PAH,-1.794,0.0500837,0.00305446,1.20994 kka2_1:4_G10A,kka2_1:4_10,Kka2,kka2_1:4,P00552,1.20995,NO,10,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.921,-3.11,1.189,,,,,,,1.862,,71.59,HOP,-2.10733,0.168804,0.00289233,1.20995 beta-lactamase_0_E87T,beta-lactamase_0_87,TEM-1,beta-lactamase_0,P62593,1.21001,NO,87,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.421,-2.787,1.366,,0.048,,B,1.04,0.92,1.159,,64.69,PAP,-1.969,0.0500837,0.00337888,1.21001 kka2_1:4_A56E,kka2_1:4_56,Kka2,kka2_1:4,P00552,1.21005,NO,56,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.083,-2.646,0.563,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.168804,0.00717715,1.21005 beta-lactamase_0_P65Y,beta-lactamase_0_65,TEM-1,beta-lactamase_0,P62593,1.21008,NO,65,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.894,-4.31,3.416,,0.098,E,B,0.52,-0.62,0.663,,40.56,HOH,-1.03233,0.0500837,0.00152776,1.21008 beta-lactamase_0_P255D,beta-lactamase_0_255,TEM-1,beta-lactamase_0,P62593,1.21009,NO,255,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.0500837,0.00499612,1.21009 beta-lactamase_0_F149R,beta-lactamase_0_149,TEM-1,beta-lactamase_0,P62593,1.21012,NO,149,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.299,-4.139,2.84,,0.195,H,A,0.58,0.11,3.518,,63.99,HHH,-1.46067,0.0500837,0.00418462,1.21012 kka2_1:4_R145H,kka2_1:4_145,Kka2,kka2_1:4,P00552,1.21028,NO,145,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.804,-3.445,1.641,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.168804,0.00846663,1.21028 beta-lactamase_0_A84R,beta-lactamase_0_84,TEM-1,beta-lactamase_0,P62593,1.21029,NO,84,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.651,-2.603,0.952,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.0500837,0.00503822,1.21029 beta-lactamase_0_M67Y,beta-lactamase_0_67,TEM-1,beta-lactamase_0,P62593,1.21029,NO,67,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-2.231,-4.282,2.051,,0.006,G,P,0.55,-0.81,24.165,24.165,65.03,HHP,-1.502,0.0500837,0.00409753,1.21029 kka2_1:8_V16E,kka2_1:8_16,Kka2,kka2_1:8,P00552,1.21031,NO,16,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-3.087,-2.983,-0.104,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.100394,0.00694011,1.21031 kka2_1:8_V16E,kka2_1:8_16,Kka2,kka2_1:8,P00552,1.21031,NO,16,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-3.087,-2.983,-0.104,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.100394,0.00694011,1.21031 beta-lactamase_0_R81F,beta-lactamase_0_81,TEM-1,beta-lactamase_0,P62593,1.21045,NO,81,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.466,-4.359,2.893,,0.218,H,A,1.2,1.66,0.332,,50,PBH,-1.60667,0.0500837,0.00499763,1.21045 kka2_1:8_E230M,kka2_1:8_230,Kka2,kka2_1:8,P00552,1.21046,NO,230,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.672,-4.815,2.143,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.100394,0.00920051,1.21046 kka2_1:8_E230M,kka2_1:8_230,Kka2,kka2_1:8,P00552,1.21046,NO,230,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.672,-4.815,2.143,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.100394,0.00920051,1.21046 beta-lactamase_0_E61S,beta-lactamase_0_61,TEM-1,beta-lactamase_0,P62593,1.2106,NO,61,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.115,-2.688,0.573,,0.775,T,a,1.04,1.29,34.763,34.763,77.62,OAA,-1.92567,0.0500837,0.00440955,1.2106 kka2_1:8_V242I,kka2_1:8_242,Kka2,kka2_1:8,P00552,1.21061,NO,242,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-2.687,-3.231,0.544,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.100394,0.0102575,1.21061 kka2_1:8_V242I,kka2_1:8_242,Kka2,kka2_1:8,P00552,1.21061,NO,242,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-2.687,-3.231,0.544,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.100394,0.0102575,1.21061 kka2_1:8_G10T,kka2_1:8_10,Kka2,kka2_1:8,P00552,1.21073,NO,10,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.921,-3.48,1.559,,,,,,,1.862,,71.59,HOP,-2.10733,0.100394,0.00289233,1.21073 kka2_1:8_G10T,kka2_1:8_10,Kka2,kka2_1:8,P00552,1.21073,NO,10,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.921,-3.48,1.559,,,,,,,1.862,,71.59,HOP,-2.10733,0.100394,0.00289233,1.21073 beta-lactamase_0_E102S,beta-lactamase_0_102,TEM-1,beta-lactamase_0,P62593,1.21083,NO,102,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.118,-2.129,0.011,,0.722,S,B,1.04,1.82,4.773,,73.08,HAH,-1.581,0.0500837,0.00486633,1.21083 kka2_1:4_R18Y,kka2_1:4_18,Kka2,kka2_1:4,P00552,1.21093,NO,18,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.055,-3.413,1.358,,0.474,T,A,1.2,0.54,8.405,8.405,71.59,ABH,-1.821,0.168804,0.00724065,1.21093 kka2_1:8_E230V,kka2_1:8_230,Kka2,kka2_1:8,P00552,1.21097,NO,230,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.672,-3.108,0.436,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.100394,0.00920051,1.21097 kka2_1:8_E230V,kka2_1:8_230,Kka2,kka2_1:8,P00552,1.21097,NO,230,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.672,-3.108,0.436,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.100394,0.00920051,1.21097 WW_domain_E178G,WW_domain_178,Yap65,WW_domain,P46937,1.21098,NO,178,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.158,-3.135,1.977,5.22323,,,,,,,,,HAH,-1.299,0.153962,0.0016738,1.21098 kka2_1:2_T130S,kka2_1:2_130,Kka2,kka2_1:2,P00552,1.21102,NO,130,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.392,-2.025,-0.367,,0.561,G,A,0.22,0.77,0.5,,92.05,HPO,-1.62633,0.295029,0.00804204,1.21102 kka2_1:4_S68R,kka2_1:4_68,Kka2,kka2_1:4,P00552,1.21112,NO,68,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.623,-1.749,-0.874,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.168804,0.00608265,1.21112 beta-lactamase_0_E164A,beta-lactamase_0_164,TEM-1,beta-lactamase_0,P62593,1.21129,NO,164,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-0.948,-3.102,2.154,,0.011,T,B,1.04,-0.4,1.011,,64.69,HAO,-1.388,0.0500837,0.00137286,1.21129 kka2_1:4_Y22M,kka2_1:4_22,Kka2,kka2_1:4,P00552,1.21135,NO,22,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-1.583,-4.724,3.141,,0.122,.,B,0.21,-0.8,1.838,,65.53,OHA,-1.80333,0.168804,0.00598977,1.21135 gb1_A250H,gb1_250,gb1,gb1,P06654,1.21139,NO,250,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.713,-4.242,2.529,,,,,,,3.465,,45.54,HHP,-1.74867,0.177985,0.00332003,1.21139 kka2_1:4_E235Q,kka2_1:4_235,Kka2,kka2_1:4,P00552,1.21139,NO,235,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.955,-2.458,0.503,,0.631,H,A,1.04,0.12,23.175,23.175,65.53,OAH,-2.07267,0.168804,0.0102806,1.21139 beta-lactamase_0_M180E,beta-lactamase_0_180,TEM-1,beta-lactamase_0,P62593,1.21155,NO,180,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-2.795,-3.532,0.737,,0.242,,B,0.55,-0.94,2.892,,77.62,PHO,-1.56433,0.0500837,0.00552048,1.21155 kka2_1:2_A248P,kka2_1:2_248,Kka2,kka2_1:2,P00552,1.21156,NO,248,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.124,-3.022,0.898,,0.825,S,b,0.46,0.46,,,92.05,HHO,-2.15,0.295029,0.0125484,1.21156 kka2_1:8_Q163I,kka2_1:8_163,Kka2,kka2_1:8,P00552,1.21175,NO,163,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.162,-3.594,1.432,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.100394,0.00719507,1.21175 kka2_1:8_Q163I,kka2_1:8_163,Kka2,kka2_1:8,P00552,1.21175,NO,163,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.162,-3.594,1.432,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.100394,0.00719507,1.21175 kka2_1:2_A13P,kka2_1:2_13,Kka2,kka2_1:2,P00552,1.21176,NO,13,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.248,-2.481,0.233,,0.689,G,A,0.46,0.99,,,92.05,OHH,-1.646,0.295029,0.00784241,1.21176 beta-lactamase_0_I140C,beta-lactamase_0_140,TEM-1,beta-lactamase_0,P62593,1.21181,NO,140,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.733,-4.792,3.059,,0.128,H,A,0.48,0.41,4.714,,73.08,PHO,-1.48733,0.0500837,0.00597777,1.21181 kka2_1:2_A247M,kka2_1:2_247,Kka2,kka2_1:2,P00552,1.21187,NO,247,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.459,-3.49,1.031,,1.01,S,A,0.46,0.65,0.828,,92.05,HHH,-2.197,0.295029,0.0102428,1.21187 kka2_1:2_L165A,kka2_1:2_165,Kka2,kka2_1:2,P00552,1.21196,NO,165,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-2.453,-2.69,0.237,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.295029,0.00801161,1.21196 kka2_1:4_S105C,kka2_1:4_105,Kka2,kka2_1:4,P00552,1.21198,NO,105,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.945,-3.198,1.253,,0.056,S,B,0.77,-1.04,3.442,,65.53,PPB,-2.17033,0.168804,0.00847233,1.21198 kka2_1:4_D156G,kka2_1:4_156,Kka2,kka2_1:4,P00552,1.21211,NO,156,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.696,-3.383,1.687,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.168804,0.00926998,1.21211 kka2_1:1_F20H,kka2_1:1_20,Kka2,kka2_1:1,P00552,1.21227,NO,20,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-3.354,-4.805,1.451,,0.935,T,B,0.58,-0.41,1.657,,92.05,HHO,-1.992,0.520039,0.00701744,1.21227 kka2_1:8_V80P,kka2_1:8_80,Kka2,kka2_1:8,P00552,1.21229,NO,80,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.144,-2.863,1.719,,0.358,E,B,1.48,-0.24,2.562,,63.64,HHH,-1.64633,0.100394,0.00488211,1.21229 kka2_1:8_V80P,kka2_1:8_80,Kka2,kka2_1:8,P00552,1.21229,NO,80,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.144,-2.863,1.719,,0.358,E,B,1.48,-0.24,2.562,,63.64,HHH,-1.64633,0.100394,0.00488211,1.21229 kka2_1:4_A172T,kka2_1:4_172,Kka2,kka2_1:4,P00552,1.21233,NO,172,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.757,-2.834,1.077,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.168804,0.0079265,1.21233 kka2_1:8_A255H,kka2_1:8_255,Kka2,kka2_1:8,P00552,1.21234,NO,255,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.715,-3.488,1.773,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.100394,0.0126809,1.21234 kka2_1:8_A255H,kka2_1:8_255,Kka2,kka2_1:8,P00552,1.21234,NO,255,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.715,-3.488,1.773,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.100394,0.0126809,1.21234 kka2_1:8_E199R,kka2_1:8_199,Kka2,kka2_1:8,P00552,1.2124,NO,199,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.234,-3.022,0.788,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.100394,0.00854122,1.2124 kka2_1:8_E199R,kka2_1:8_199,Kka2,kka2_1:8,P00552,1.2124,NO,199,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.234,-3.022,0.788,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.100394,0.00854122,1.2124 beta-lactamase_0_I140N,beta-lactamase_0_140,TEM-1,beta-lactamase_0,P62593,1.21243,NO,140,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.733,-4.2,2.467,,0.128,H,A,0.48,0.41,4.714,,73.08,PHO,-1.48733,0.0500837,0.00597777,1.21243 kka2_1:8_A9M,kka2_1:8_9,Kka2,kka2_1:8,P00552,1.21253,NO,9,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.079,-2.864,0.785,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.100394,0.00273264,1.21253 kka2_1:8_A9M,kka2_1:8_9,Kka2,kka2_1:8,P00552,1.21253,NO,9,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.079,-2.864,0.785,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.100394,0.00273264,1.21253 kka2_1:8_V46G,kka2_1:8_46,Kka2,kka2_1:8,P00552,1.21254,NO,46,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-2.62,-2.793,0.173,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.100394,0.00631301,1.21254 kka2_1:8_V46G,kka2_1:8_46,Kka2,kka2_1:8,P00552,1.21254,NO,46,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-2.62,-2.793,0.173,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.100394,0.00631301,1.21254 kka2_1:2_V16S,kka2_1:2_16,Kka2,kka2_1:2,P00552,1.21255,NO,16,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-3.087,-2.803,-0.284,,0.742,T,A,0.44,0.34,1.746,,71.59,HHA,-2.211,0.295029,0.00694011,1.21255 kka2_1:8_Y22M,kka2_1:8_22,Kka2,kka2_1:8,P00552,1.21259,NO,22,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-1.583,-4.724,3.141,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.100394,0.00598977,1.21259 kka2_1:8_Y22M,kka2_1:8_22,Kka2,kka2_1:8,P00552,1.21259,NO,22,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-1.583,-4.724,3.141,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.100394,0.00598977,1.21259 kka2_1:2_R239H,kka2_1:2_239,Kka2,kka2_1:2,P00552,1.21273,NO,239,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.949,-2.896,-0.053,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.295029,0.00835326,1.21273 kka2_1:8_Q163R,kka2_1:8_163,Kka2,kka2_1:8,P00552,1.21273,NO,163,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.162,-2.527,0.365,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.100394,0.00719507,1.21273 kka2_1:8_Q163R,kka2_1:8_163,Kka2,kka2_1:8,P00552,1.21273,NO,163,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.162,-2.527,0.365,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.100394,0.00719507,1.21273 kka2_1:4_N200G,kka2_1:4_200,Kka2,kka2_1:4,P00552,1.21283,NO,200,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-2.446,-1.948,-0.498,,0.756,T,L,0.61,-0.08,1.746,,64.39,APO,-2.08,0.168804,0.00838549,1.21283 kka2_1:4_E160A,kka2_1:4_160,Kka2,kka2_1:4,P00552,1.21284,NO,160,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.683,-2.356,0.673,,0.989,G,A,1.04,2.28,2.531,,71.59,AAA,-1.36133,0.168804,0.00935762,1.21284 kka2_1:8_A35W,kka2_1:8_35,Kka2,kka2_1:8,P00552,1.21285,NO,35,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.127,-5.562,3.435,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.100394,0.00630016,1.21285 kka2_1:8_A35W,kka2_1:8_35,Kka2,kka2_1:8,P00552,1.21285,NO,35,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.127,-5.562,3.435,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.100394,0.00630016,1.21285 kka2_1:8_Q4A,kka2_1:8_4,Kka2,kka2_1:8,P00552,1.21286,NO,4,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.361,-2.857,0.496,,,,,,,2.026,,71.59,APA,-1.95533,0.100394,0.00239179,1.21286 kka2_1:8_Q4A,kka2_1:8_4,Kka2,kka2_1:8,P00552,1.21286,NO,4,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.361,-2.857,0.496,,,,,,,2.026,,71.59,APA,-1.95533,0.100394,0.00239179,1.21286 kka2_1:2_G234I,kka2_1:2_234,Kka2,kka2_1:2,P00552,1.21291,NO,234,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-2.9,-4.067,1.167,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.295029,0.00984449,1.21291 kka2_1:8_A255N,kka2_1:8_255,Kka2,kka2_1:8,P00552,1.21291,NO,255,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.715,-3.829,2.114,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.100394,0.0126809,1.21291 kka2_1:8_A255N,kka2_1:8_255,Kka2,kka2_1:8,P00552,1.21291,NO,255,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.715,-3.829,2.114,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.100394,0.0126809,1.21291 beta-lactamase_0_E46A,beta-lactamase_0_46,TEM-1,beta-lactamase_0,P62593,1.21294,NO,46,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.94,-2.586,0.646,,0.021,E,B,1.04,0.14,30.306,30.306,59.44,HAH,-2.079,0.0500837,0.00427568,1.21294 beta-lactamase_0_I280R,beta-lactamase_0_280,TEM-1,beta-lactamase_0,P62593,1.21298,NO,280,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.0500837,0.0530888,1.21298 kka2_1:8_L39I,kka2_1:8_39,Kka2,kka2_1:8,P00552,1.21298,NO,39,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.223,-2.15,0.927,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.100394,0.00493618,1.21298 kka2_1:8_L39I,kka2_1:8_39,Kka2,kka2_1:8,P00552,1.21298,NO,39,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.223,-2.15,0.927,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.100394,0.00493618,1.21298 kka2_1:2_S114R,kka2_1:2_114,Kka2,kka2_1:2,P00552,1.213,NO,114,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.527,-2.846,0.319,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.295029,0.00705262,1.213 kka2_1:8_I2K,kka2_1:8_2,Kka2,kka2_1:8,P00552,1.21305,NO,2,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.787,-3.536,1.749,,,,,,,,,71.59,HHA,-1.92433,0.100394,0.00246644,1.21305 kka2_1:8_I2K,kka2_1:8_2,Kka2,kka2_1:8,P00552,1.21305,NO,2,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.787,-3.536,1.749,,,,,,,,,71.59,HHA,-1.92433,0.100394,0.00246644,1.21305 kka2_1:8_A166I,kka2_1:8_166,Kka2,kka2_1:8,P00552,1.21325,NO,166,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.407,-3.972,1.565,,0.534,,B,1.04,1.03,13.995,13.995,71.59,HHO,-2.421,0.100394,0.00799912,1.21325 kka2_1:8_A166I,kka2_1:8_166,Kka2,kka2_1:8,P00552,1.21325,NO,166,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.407,-3.972,1.565,,0.534,,B,1.04,1.03,13.995,13.995,71.59,HHO,-2.421,0.100394,0.00799912,1.21325 kka2_1:8_V242R,kka2_1:8_242,Kka2,kka2_1:8,P00552,1.21325,NO,242,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-2.687,-2.299,-0.388,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.100394,0.0102575,1.21325 kka2_1:8_V242R,kka2_1:8_242,Kka2,kka2_1:8,P00552,1.21325,NO,242,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-2.687,-2.299,-0.388,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.100394,0.0102575,1.21325 kka2_1:4_E111T,kka2_1:4_111,Kka2,kka2_1:4,P00552,1.2134,NO,111,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.28,-2.755,0.475,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.168804,0.00746789,1.2134 kka2_1:4_A9T,kka2_1:4_9,Kka2,kka2_1:4,P00552,1.21343,NO,9,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.079,-3.282,1.203,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.168804,0.00273264,1.21343 kka2_1:8_Q252P,kka2_1:8_252,Kka2,kka2_1:8,P00552,1.21344,NO,252,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.63,-3.996,1.366,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.100394,0.0121001,1.21344 kka2_1:8_Q252P,kka2_1:8_252,Kka2,kka2_1:8,P00552,1.21344,NO,252,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.63,-3.996,1.366,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.100394,0.0121001,1.21344 kka2_1:8_R258K,kka2_1:8_258,Kka2,kka2_1:8,P00552,1.21351,NO,258,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.626,-3.325,1.699,,0.316,H,A,0.16,-0.85,5.58,,53.03,HBH,-1.25933,0.100394,0.00983174,1.21351 kka2_1:8_R258K,kka2_1:8_258,Kka2,kka2_1:8,P00552,1.21351,NO,258,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.626,-3.325,1.699,,0.316,H,A,0.16,-0.85,5.58,,53.03,HBH,-1.25933,0.100394,0.00983174,1.21351 WW_domain_Q195K,WW_domain_195,Yap65,WW_domain,P46937,1.21365,NO,195,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-1.839,-2.032,0.193,5.22735,,,,,,1.803,,70.04,APP,-1.719,0.153962,0.00394344,1.21365 kka2_1:4_D180E,kka2_1:4_180,Kka2,kka2_1:4,P00552,1.21367,NO,180,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.416,-2.535,0.119,,1.03,S,a,0.29,1.5,14.668,14.668,71.59,OAO,-2.02933,0.168804,0.00756412,1.21367 kka2_1:8_R177V,kka2_1:8_177,Kka2,kka2_1:8,P00552,1.21367,NO,177,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.282,-3.636,1.354,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.100394,0.00768224,1.21367 kka2_1:8_R177V,kka2_1:8_177,Kka2,kka2_1:8,P00552,1.21367,NO,177,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.282,-3.636,1.354,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.100394,0.00768224,1.21367 kka2_1:8_E149N,kka2_1:8_149,Kka2,kka2_1:8,P00552,1.21368,NO,149,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.994,-2.918,0.924,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.100394,0.00803343,1.21368 kka2_1:8_E149N,kka2_1:8_149,Kka2,kka2_1:8,P00552,1.21368,NO,149,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.994,-2.918,0.924,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.100394,0.00803343,1.21368 kka2_1:8_Q4I,kka2_1:8_4,Kka2,kka2_1:8,P00552,1.21368,NO,4,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.361,-3.887,1.526,,,,,,,2.026,,71.59,APA,-1.95533,0.100394,0.00239179,1.21368 kka2_1:8_Q4I,kka2_1:8_4,Kka2,kka2_1:8,P00552,1.21368,NO,4,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.361,-3.887,1.526,,,,,,,2.026,,71.59,APA,-1.95533,0.100394,0.00239179,1.21368 kka2_1:4_R239F,kka2_1:4_239,Kka2,kka2_1:4,P00552,1.21369,NO,239,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.949,-4.366,1.417,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.168804,0.00835326,1.21369 kka2_1:4_H139K,kka2_1:4_139,Kka2,kka2_1:4,P00552,1.21371,NO,139,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-2.809,-2.699,-0.11,,0.471,H,A,0.17,0.68,12.761,12.761,63.64,BBB,-2.22,0.168804,0.00734779,1.21371 kka2_1:2_S105A,kka2_1:2_105,Kka2,kka2_1:2,P00552,1.21385,NO,105,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.945,-1.746,-0.199,,0.056,S,B,0.27,-1.04,3.442,,65.53,PPB,-2.17033,0.295029,0.00847233,1.21385 kka2_1:8_A137M,kka2_1:8_137,Kka2,kka2_1:8,P00552,1.21393,NO,137,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.156,-4.232,2.076,,0.029,H,A,1.04,0.34,2.886,,63.26,PHB,-2.559,0.100394,0.00515054,1.21393 kka2_1:8_A137M,kka2_1:8_137,Kka2,kka2_1:8,P00552,1.21393,NO,137,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.156,-4.232,2.076,,0.029,H,A,1.04,0.34,2.886,,63.26,PHB,-2.559,0.100394,0.00515054,1.21393 kka2_1:8_Y244L,kka2_1:8_244,Kka2,kka2_1:8,P00552,1.21393,NO,244,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-0.775,-3.161,2.386,,0.066,H,A,1.25,-0.64,,,,HHO,-1.41267,0.100394,0.00453187,1.21393 kka2_1:8_Y244L,kka2_1:8_244,Kka2,kka2_1:8,P00552,1.21393,NO,244,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-0.775,-3.161,2.386,,0.066,H,A,1.25,-0.64,,,,HHO,-1.41267,0.100394,0.00453187,1.21393 kka2_1:4_A35Q,kka2_1:4_35,Kka2,kka2_1:4,P00552,1.21395,NO,35,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.127,-3.255,1.128,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.168804,0.00630016,1.21395 kka2_1:8_S251D,kka2_1:8_251,Kka2,kka2_1:8,P00552,1.21396,NO,251,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.636,-2.837,0.201,,0.712,H,A,0.27,-0.25,,,71.59,APP,-2.09367,0.100394,0.0138916,1.21396 kka2_1:8_S251D,kka2_1:8_251,Kka2,kka2_1:8,P00552,1.21396,NO,251,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.636,-2.837,0.201,,0.712,H,A,0.27,-0.25,,,71.59,APP,-2.09367,0.100394,0.0138916,1.21396 kka2_1:8_L7Q,kka2_1:8_7,Kka2,kka2_1:8,P00552,1.21402,NO,7,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.926,-3.782,1.856,,,,,,,,,71.59,OHB,-2.12333,0.100394,0.00269456,1.21402 kka2_1:8_L7Q,kka2_1:8_7,Kka2,kka2_1:8,P00552,1.21402,NO,7,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.926,-3.782,1.856,,,,,,,,,71.59,OHB,-2.12333,0.100394,0.00269456,1.21402 beta-lactamase_0_K30L,beta-lactamase_0_30,TEM-1,beta-lactamase_0,P62593,1.21406,NO,30,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-2.307,-3.404,1.097,,0.142,H,A,2.34,-0.65,1.491,,93.01,HBH,-2.32833,0.0500837,0.00448593,1.21406 kka2_1:8_A13F,kka2_1:8_13,Kka2,kka2_1:8,P00552,1.21408,NO,13,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.248,-4.439,2.191,,0.689,G,A,1.04,0.99,14.966,14.966,92.05,OHH,-1.646,0.100394,0.00784241,1.21408 kka2_1:8_A13F,kka2_1:8_13,Kka2,kka2_1:8,P00552,1.21408,NO,13,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.248,-4.439,2.191,,0.689,G,A,1.04,0.99,14.966,14.966,92.05,OHH,-1.646,0.100394,0.00784241,1.21408 kka2_1:2_L243A,kka2_1:2_243,Kka2,kka2_1:2,P00552,1.2141,NO,243,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-2.651,-2.102,-0.549,,0.277,H,A,1.59,-0.67,13.165,13.165,92.05,HHH,-2.03767,0.295029,0.00884927,1.2141 kka2_1:4_S54T,kka2_1:4_54,Kka2,kka2_1:4,P00552,1.2141,NO,54,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.471,-2.979,0.508,,0.408,S,b,0.27,1.01,17.332,17.332,71.59,HPO,-2.259,0.168804,0.00782867,1.2141 kka2_1:4_V80C,kka2_1:4_80,Kka2,kka2_1:4,P00552,1.21422,NO,80,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.144,-4.756,3.612,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.168804,0.00488211,1.21422 kka2_1:8_R44A,kka2_1:8_44,Kka2,kka2_1:8,P00552,1.21423,NO,44,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.062,-2.384,0.322,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.100394,0.00745043,1.21423 kka2_1:8_R44A,kka2_1:8_44,Kka2,kka2_1:8,P00552,1.21423,NO,44,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.062,-2.384,0.322,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.100394,0.00745043,1.21423 kka2_1:2_T125M,kka2_1:2_125,Kka2,kka2_1:2,P00552,1.21426,NO,125,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.622,-4.759,2.137,,0.791,T,A,0.22,0.33,2.029,,92.05,BPH,-1.56933,0.295029,0.00821755,1.21426 kka2_1:8_R145N,kka2_1:8_145,Kka2,kka2_1:8,P00552,1.21429,NO,145,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.804,-3.787,1.983,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.100394,0.00846663,1.21429 kka2_1:8_R145N,kka2_1:8_145,Kka2,kka2_1:8,P00552,1.21429,NO,145,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.804,-3.787,1.983,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.100394,0.00846663,1.21429 kka2_1:8_I246M,kka2_1:8_246,Kka2,kka2_1:8,P00552,1.2143,NO,246,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-2.008,-2.785,0.777,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.100394,0.0139479,1.2143 kka2_1:8_I246M,kka2_1:8_246,Kka2,kka2_1:8,P00552,1.2143,NO,246,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-2.008,-2.785,0.777,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.100394,0.0139479,1.2143 kka2_1:8_E199H,kka2_1:8_199,Kka2,kka2_1:8,P00552,1.21444,NO,199,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.234,-3.025,0.791,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.100394,0.00854122,1.21444 kka2_1:8_E199H,kka2_1:8_199,Kka2,kka2_1:8,P00552,1.21444,NO,199,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.234,-3.025,0.791,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.100394,0.00854122,1.21444 kka2_1:4_Q136V,kka2_1:4_136,Kka2,kka2_1:4,P00552,1.21447,NO,136,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-3.021,-3.774,0.753,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.168804,0.00624149,1.21447 beta-lactamase_0_P217E,beta-lactamase_0_217,TEM-1,beta-lactamase_0,P62593,1.21455,NO,217,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-2.062,-2.651,0.589,,0.496,I,A,0.52,-0.33,1.087,,74.48,OOH,-1.64333,0.0500837,0.00463211,1.21455 kka2_1:2_A14I,kka2_1:2_14,Kka2,kka2_1:2,P00552,1.21455,NO,14,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.837,-3.179,1.342,,0.728,G,A,0.46,0.7,0.36,,71.59,HHH,-1.82567,0.295029,0.00706614,1.21455 kka2_1:4_T72M,kka2_1:4_72,Kka2,kka2_1:4,P00552,1.21459,NO,72,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.38,-3.59,1.21,,0.784,H,A,0.82,0.29,6.463,,65.53,HPP,-2.238,0.168804,0.00750756,1.21459 kka2_1:4_K138Q,kka2_1:4_138,Kka2,kka2_1:4,P00552,1.21464,NO,138,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-2.5,-2.969,0.469,,0.594,H,A,1.3,0.98,21.267,21.267,71.59,HBB,-2.48833,0.168804,0.00628542,1.21464 beta-lactamase_0_I93A,beta-lactamase_0_93,TEM-1,beta-lactamase_0,P62593,1.21465,NO,93,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.401,-3.13,1.729,,0.128,E,B,0.48,0.44,1.266,,67.83,BHB,-1.873,0.0500837,0.00527066,1.21465 kka2_1:8_A172R,kka2_1:8_172,Kka2,kka2_1:8,P00552,1.21465,NO,172,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.757,-2.665,0.908,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.100394,0.0079265,1.21465 kka2_1:8_A172R,kka2_1:8_172,Kka2,kka2_1:8,P00552,1.21465,NO,172,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.757,-2.665,0.908,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.100394,0.0079265,1.21465 kka2_1:2_G234V,kka2_1:2_234,Kka2,kka2_1:2,P00552,1.21467,NO,234,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-2.9,-2.894,-0.006,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.295029,0.00984449,1.21467 kka2_1:8_V80C,kka2_1:8_80,Kka2,kka2_1:8,P00552,1.21474,NO,80,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.144,-4.756,3.612,,0.358,E,B,1.48,-0.24,2.562,,63.64,HHH,-1.64633,0.100394,0.00488211,1.21474 kka2_1:8_V80C,kka2_1:8_80,Kka2,kka2_1:8,P00552,1.21474,NO,80,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.144,-4.756,3.612,,0.358,E,B,1.48,-0.24,2.562,,63.64,HHH,-1.64633,0.100394,0.00488211,1.21474 beta-lactamase_0_E62Q,beta-lactamase_0_62,TEM-1,beta-lactamase_0,P62593,1.21486,NO,62,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.193,-2.5,1.307,,0.342,S,B,1.04,-0.3,5.784,,73.08,AAB,-1.417,0.0500837,0.00264802,1.21486 kka2_1:4_W24V,kka2_1:4_24,Kka2,kka2_1:4,P00552,1.21492,NO,24,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-1.779,-2.484,0.705,,0.477,E,B,1.51,-0.21,2.666,,56.06,AHH,-2.24467,0.168804,0.00631564,1.21492 beta-lactamase_0_D99N,beta-lactamase_0_99,TEM-1,beta-lactamase_0,P62593,1.21504,NO,99,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.191,-3.466,2.275,,0.402,G,A,0.75,0.36,0.374,,64.69,PAH,-1.794,0.0500837,0.00305446,1.21504 kka2_1:4_R44K,kka2_1:4_44,Kka2,kka2_1:4,P00552,1.21508,NO,44,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.062,-2.763,0.701,,0.487,S,B,1.2,-0.35,5.71,,71.59,OBO,-1.80767,0.168804,0.00745043,1.21508 kka2_1:8_L53I,kka2_1:8_53,Kka2,kka2_1:8,P00552,1.21508,NO,53,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-2.681,-2.859,0.178,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.100394,0.00671168,1.21508 kka2_1:8_L53I,kka2_1:8_53,Kka2,kka2_1:8,P00552,1.21508,NO,53,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-2.681,-2.859,0.178,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.100394,0.00671168,1.21508 kka2_1:4_L7R,kka2_1:4_7,Kka2,kka2_1:4,P00552,1.21512,NO,7,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.926,-3.722,1.796,,,,,,,3.012,,71.59,OHB,-2.12333,0.168804,0.00269456,1.21512 kka2_1:2_A168F,kka2_1:2_168,Kka2,kka2_1:2,P00552,1.21519,NO,168,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.989,-3.458,1.469,,0.67,H,A,0.46,0.15,25.546,25.546,64.39,OHA,-2.12933,0.295029,0.00806773,1.21519 kka2_1:4_A247Y,kka2_1:4_247,Kka2,kka2_1:4,P00552,1.21523,NO,247,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.459,-4.278,1.819,,1.01,S,A,0.46,0.65,,,92.05,HHH,-2.197,0.168804,0.0102428,1.21523 kka2_1:4_A87G,kka2_1:4_87,Kka2,kka2_1:4,P00552,1.2153,NO,87,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.917,-2.002,0.085,,1.039,S,L,0.46,1.57,22.675,22.675,65.53,AHO,-1.822,0.168804,0.00791281,1.2153 beta-lactamase_0_A148I,beta-lactamase_0_148,TEM-1,beta-lactamase_0,P62593,1.21532,NO,148,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.757,-4.049,2.292,,0.379,H,A,0.46,-0.55,19.42,19.42,72.73,PHH,-1.40167,0.0500837,0.00547053,1.21532 beta-lactamase_0_T158F,beta-lactamase_0_158,TEM-1,beta-lactamase_0,P62593,1.21542,NO,158,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.116,-4.177,3.061,,0.036,,B,0.22,-0.85,1.041,,69.58,HPB,-1.269,0.0500837,0.00341825,1.21542 kka2_1:8_R177F,kka2_1:8_177,Kka2,kka2_1:8,P00552,1.21546,NO,177,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.282,-4.359,2.077,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.100394,0.00768224,1.21546 kka2_1:8_R177F,kka2_1:8_177,Kka2,kka2_1:8,P00552,1.21546,NO,177,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.282,-4.359,2.077,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.100394,0.00768224,1.21546 kka2_1:2_Y244M,kka2_1:2_244,Kka2,kka2_1:2,P00552,1.21551,NO,244,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-0.775,-4.508,3.733,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.295029,0.00453187,1.21551 kka2_1:8_D5H,kka2_1:8_5,Kka2,kka2_1:8,P00552,1.21556,NO,5,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.306,-4.185,2.879,,,,,,,1.147,,71.59,PAO,-1.784,0.100394,0.00222864,1.21556 kka2_1:8_D5H,kka2_1:8_5,Kka2,kka2_1:8,P00552,1.21556,NO,5,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.306,-4.185,2.879,,,,,,,1.147,,71.59,PAO,-1.784,0.100394,0.00222864,1.21556 kka2_1:8_A176N,kka2_1:8_176,Kka2,kka2_1:8,P00552,1.21567,NO,176,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.621,-3.03,1.409,,0.806,H,A,0.46,-0.03,18.904,18.904,65.53,BHB,-2.26667,0.100394,0.0083587,1.21567 kka2_1:8_A176N,kka2_1:8_176,Kka2,kka2_1:8,P00552,1.21567,NO,176,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.621,-3.03,1.409,,0.806,H,A,0.46,-0.03,18.904,18.904,65.53,BHB,-2.26667,0.100394,0.0083587,1.21567 kka2_1:8_R44S,kka2_1:8_44,Kka2,kka2_1:8,P00552,1.21568,NO,44,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.062,-2.625,0.563,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.100394,0.00745043,1.21568 kka2_1:8_R44S,kka2_1:8_44,Kka2,kka2_1:8,P00552,1.21568,NO,44,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.062,-2.625,0.563,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.100394,0.00745043,1.21568 beta-lactamase_0_A268G,beta-lactamase_0_268,TEM-1,beta-lactamase_0,P62593,1.21573,NO,268,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.0500837,0.0102525,1.21573 kka2_1:8_A166F,kka2_1:8_166,Kka2,kka2_1:8,P00552,1.21587,NO,166,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.407,-4.424,2.017,,0.534,,B,1.04,1.03,13.995,13.995,71.59,HHO,-2.421,0.100394,0.00799912,1.21587 kka2_1:8_A166F,kka2_1:8_166,Kka2,kka2_1:8,P00552,1.21587,NO,166,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.407,-4.424,2.017,,0.534,,B,1.04,1.03,13.995,13.995,71.59,HHO,-2.421,0.100394,0.00799912,1.21587 kka2_1:8_T73M,kka2_1:8_73,Kka2,kka2_1:8,P00552,1.21588,NO,73,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.51,-3.216,0.706,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.100394,0.00628605,1.21588 kka2_1:8_T73M,kka2_1:8_73,Kka2,kka2_1:8,P00552,1.21588,NO,73,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.51,-3.216,0.706,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.100394,0.00628605,1.21588 kka2_1:4_E199D,kka2_1:4_199,Kka2,kka2_1:4,P00552,1.21594,NO,199,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.234,-2.172,-0.062,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.168804,0.00854122,1.21594 beta-lactamase_39_E210A,beta-lactamase_39_210,TEM-1,beta-lactamase_39,P62593,1.21601,NO,210,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.319,-3.162,0.843,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.0495842,0.00663582,1.21601 kka2_1:8_E199Q,kka2_1:8_199,Kka2,kka2_1:8,P00552,1.21602,NO,199,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.234,-3.039,0.805,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.100394,0.00854122,1.21602 kka2_1:8_E199Q,kka2_1:8_199,Kka2,kka2_1:8,P00552,1.21602,NO,199,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.234,-3.039,0.805,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.100394,0.00854122,1.21602 beta-lactamase_0_K232C,beta-lactamase_0_232,TEM-1,beta-lactamase_0,P62593,1.21603,NO,232,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.012,-5.13,4.118,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.0500837,0.00313441,1.21603 kka2_1:8_C209T,kka2_1:8_209,Kka2,kka2_1:8,P00552,1.21609,NO,209,C,T,CT,Special,Polar,5.07,5.6,0.53,149,121,119,-2,108.5,116.1,7.6,-0.906,-3.473,2.567,,,,a,1.5,-0.89,0.391,,19.32,AOO,-0.903,0.100394,0.00260862,1.21609 kka2_1:8_C209T,kka2_1:8_209,Kka2,kka2_1:8,P00552,1.21609,NO,209,C,T,CT,Special,Polar,5.07,5.6,0.53,149,121,119,-2,108.5,116.1,7.6,-0.906,-3.473,2.567,,,,a,1.5,-0.89,0.391,,19.32,AOO,-0.903,0.100394,0.00260862,1.21609 kka2_1:4_Q100C,kka2_1:4_100,Kka2,kka2_1:4,P00552,1.21621,NO,100,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.77,-3.712,0.942,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.168804,0.0066405,1.21621 kka2_1:2_D5Y,kka2_1:2_5,Kka2,kka2_1:2,P00552,1.21629,NO,5,D,Y,DY,negativeCharge,Hydrophobic,5.0516,5.66,0.6084,160,133,181,48,111.1,193.6,82.5,-1.306,-4.118,2.812,,,,,,,,,71.59,PAO,-1.784,0.295029,0.00222864,1.21629 kka2_1:8_T130A,kka2_1:8_130,Kka2,kka2_1:8,P00552,1.21644,NO,130,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.392,-1.951,-0.441,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.100394,0.00804204,1.21644 kka2_1:8_T130A,kka2_1:8_130,Kka2,kka2_1:8,P00552,1.21644,NO,130,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.392,-1.951,-0.441,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.100394,0.00804204,1.21644 kka2_1:8_P132M,kka2_1:8_132,Kka2,kka2_1:8,P00552,1.21653,NO,132,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.775,-4.731,3.956,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.100394,0.0018489,1.21653 kka2_1:8_P132M,kka2_1:8_132,Kka2,kka2_1:8,P00552,1.21653,NO,132,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.775,-4.731,3.956,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.100394,0.0018489,1.21653 kka2_1:2_E3L,kka2_1:2_3,Kka2,kka2_1:2,P00552,1.21685,NO,3,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.199,-3.455,1.256,,,,,,,7.22,,92.05,HAP,-2.11567,0.295029,0.00267607,1.21685 kka2_1:2_G151D,kka2_1:2_151,Kka2,kka2_1:2,P00552,1.21689,NO,151,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.873,-2.683,1.81,,0.678,T,l,0.29,1.36,1.357,,49.62,HOH,-1.11433,0.295029,0.00339918,1.21689 kka2_1:8_H106D,kka2_1:8_106,Kka2,kka2_1:8,P00552,1.2169,NO,106,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-3.13,-2.351,-0.779,,1.065,,a,0.87,-0.95,15.956,15.956,71.59,PBH,-2.10433,0.100394,0.00730778,1.2169 kka2_1:8_H106D,kka2_1:8_106,Kka2,kka2_1:8,P00552,1.2169,NO,106,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-3.13,-2.351,-0.779,,1.065,,a,0.87,-0.95,15.956,15.956,71.59,PBH,-2.10433,0.100394,0.00730778,1.2169 kka2_1:4_D23S,kka2_1:4_23,Kka2,kka2_1:4,P00552,1.21696,NO,23,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.459,-2.448,-0.011,,0.695,E,B,0.75,-0.65,2.416,,65.53,HAH,-1.94033,0.168804,0.007195,1.21696 beta-lactamase_0_G154C,beta-lactamase_0_154,TEM-1,beta-lactamase_0,P62593,1.21698,NO,154,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-0.823,-5.058,4.235,,0.54,T,l,0.29,-0.56,3.629,,64.69,HOA,-1.635,0.0500837,0.00180205,1.21698 kka2_1:4_A13C,kka2_1:4_13,Kka2,kka2_1:4,P00552,1.21702,NO,13,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.248,-3.798,1.55,,0.689,G,A,0.46,0.99,,,92.05,OHH,-1.646,0.168804,0.00784241,1.21702 kka2_1:4_T130M,kka2_1:4_130,Kka2,kka2_1:4,P00552,1.21704,NO,130,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.392,-3.607,1.215,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.168804,0.00804204,1.21704 kka2_1:4_L81I,kka2_1:4_81,Kka2,kka2_1:4,P00552,1.21708,NO,81,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.427,-1.722,0.295,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.168804,0.00805839,1.21708 kka2_1:8_S114M,kka2_1:8_114,Kka2,kka2_1:8,P00552,1.2172,NO,114,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.527,-3.615,1.088,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.100394,0.00705262,1.2172 kka2_1:8_S114M,kka2_1:8_114,Kka2,kka2_1:8,P00552,1.2172,NO,114,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.527,-3.615,1.088,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.100394,0.00705262,1.2172 kka2_1:4_G164H,kka2_1:4_164,Kka2,kka2_1:4,P00552,1.21723,NO,164,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.869,-4.642,3.773,,0.862,T,l,0.75,1.45,1.539,,64.39,POH,-1.828,0.168804,0.00442091,1.21723 kka2_1:8_E230C,kka2_1:8_230,Kka2,kka2_1:8,P00552,1.21727,NO,230,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.672,-3.614,0.942,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.100394,0.00920051,1.21727 kka2_1:8_E230C,kka2_1:8_230,Kka2,kka2_1:8,P00552,1.21727,NO,230,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.672,-3.614,0.942,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.100394,0.00920051,1.21727 kka2_1:8_R177K,kka2_1:8_177,Kka2,kka2_1:8,P00552,1.21733,NO,177,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.282,-3.03,0.748,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.100394,0.00768224,1.21733 kka2_1:8_R177K,kka2_1:8_177,Kka2,kka2_1:8,P00552,1.21733,NO,177,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.282,-3.03,0.748,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.100394,0.00768224,1.21733 beta-lactamase_0_R239G,beta-lactamase_0_239,TEM-1,beta-lactamase_0,P62593,1.21743,NO,239,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-0.819,-3.876,3.057,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.0500837,0.00213852,1.21743 kka2_1:4_P167W,kka2_1:4_167,Kka2,kka2_1:4,P00552,1.21749,NO,167,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-2.403,-5.529,3.126,,0.18,H,A,0.52,0.75,3.6,,64.39,HOH,-2.26633,0.168804,0.00543203,1.21749 kka2_1:8_D5L,kka2_1:8_5,Kka2,kka2_1:8,P00552,1.21749,NO,5,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.306,-3.538,2.232,,,,,,,1.147,,71.59,PAO,-1.784,0.100394,0.00222864,1.21749 kka2_1:8_D5L,kka2_1:8_5,Kka2,kka2_1:8,P00552,1.21749,NO,5,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.306,-3.538,2.232,,,,,,,1.147,,71.59,PAO,-1.784,0.100394,0.00222864,1.21749 beta-lactamase_0_T269D,beta-lactamase_0_269,TEM-1,beta-lactamase_0,P62593,1.21754,NO,269,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.156,-3.518,1.362,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.0500837,0.00950944,1.21754 kka2_1:4_A191L,kka2_1:4_191,Kka2,kka2_1:4,P00552,1.21761,NO,191,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.831,-3.249,2.418,,,.,b,0.46,-0.94,2.046,,50,AHO,-0.868667,0.168804,0.00338807,1.21761 kka2_1:4_D127N,kka2_1:4_127,Kka2,kka2_1:4,P00552,1.21771,NO,127,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.364,-3.671,2.307,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.168804,0.00660501,1.21771 kka2_1:4_G10M,kka2_1:4_10,Kka2,kka2_1:4,P00552,1.21779,NO,10,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.921,-4.699,2.778,,,,,,,1.862,,71.59,HOP,-2.10733,0.168804,0.00289233,1.21779 kka2_1:4_A79E,kka2_1:4_79,Kka2,kka2_1:4,P00552,1.21787,NO,79,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.368,-2.303,-0.065,,0.563,.,B,0.46,-0.43,2.291,,71.59,HHH,-1.752,0.168804,0.00664821,1.21787 kka2_1:8_D250N,kka2_1:8_250,Kka2,kka2_1:8,P00552,1.21799,NO,250,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.015,-2.686,1.671,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.100394,0.0177103,1.21799 kka2_1:8_D250N,kka2_1:8_250,Kka2,kka2_1:8,P00552,1.21799,NO,250,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.015,-2.686,1.671,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.100394,0.0177103,1.21799 kka2_1:8_L47V,kka2_1:8_47,Kka2,kka2_1:8,P00552,1.21799,NO,47,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.265,-2.308,1.043,,0.139,E,B,1.59,-0.86,5.086,,63.26,HHH,-1.77933,0.100394,0.00509386,1.21799 kka2_1:8_L47V,kka2_1:8_47,Kka2,kka2_1:8,P00552,1.21799,NO,47,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.265,-2.308,1.043,,0.139,E,B,1.59,-0.86,5.086,,63.26,HHH,-1.77933,0.100394,0.00509386,1.21799 beta-lactamase_0_H94S,beta-lactamase_0_94,TEM-1,beta-lactamase_0,P62593,1.21803,NO,94,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-2.5,-3.499,0.999,,0.776,,B,0.17,1.24,1.176,,77.62,HBH,-1.872,0.0500837,0.00389226,1.21803 beta-lactamase_0_P217K,beta-lactamase_0_217,TEM-1,beta-lactamase_0,P62593,1.21805,NO,217,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-2.062,-2.687,0.625,,0.496,I,A,0.52,-0.33,1.087,,74.48,OOH,-1.64333,0.0500837,0.00463211,1.21805 beta-lactamase_0_E108I,beta-lactamase_0_108,TEM-1,beta-lactamase_0,P62593,1.21812,NO,108,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.46,-4.133,2.673,,0.572,G,A,1.04,1.87,8.602,8.602,72.73,PAB,-1.437,0.0500837,0.00413372,1.21812 kka2_1:2_K175V,kka2_1:2_175,Kka2,kka2_1:2,P00552,1.21817,NO,175,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-2.897,-2.802,-0.095,,0.579,H,A,1.3,0.51,15.629,15.629,71.59,HBH,-1.82333,0.295029,0.00693093,1.21817 beta-lactamase_0_K30V,beta-lactamase_0_30,TEM-1,beta-lactamase_0,P62593,1.21821,NO,30,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-2.307,-2.807,0.5,,0.142,H,A,2.34,-0.65,1.491,,93.01,HBH,-2.32833,0.0500837,0.00448593,1.21821 beta-lactamase_0_K190L,beta-lactamase_0_190,TEM-1,beta-lactamase_0,P62593,1.21827,NO,190,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-1.994,-3.527,1.533,,0.371,H,A,2.34,0.16,16.606,16.606,77.62,BBH,-1.64167,0.0500837,0.00574527,1.21827 kka2_1:2_Q252T,kka2_1:2_252,Kka2,kka2_1:2,P00552,1.21832,NO,252,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.63,-2.832,0.202,,0.906,H,A,0.64,0.35,5.613,,92.05,PPB,-2.20733,0.295029,0.0121001,1.21832 beta-lactamase_0_R275D,beta-lactamase_0_275,TEM-1,beta-lactamase_0,P62593,1.21842,NO,275,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.0500837,0.0141984,1.21842 kka2_1:2_E111V,kka2_1:2_111,Kka2,kka2_1:2,P00552,1.21845,NO,111,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.28,-2.806,0.526,,0.155,H,A,1.52,-1.14,2.792,,65.53,HAB,-2.27833,0.295029,0.00746789,1.21845 kka2_1:8_E3F,kka2_1:8_3,Kka2,kka2_1:8,P00552,1.21857,NO,3,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.199,-3.772,1.573,,,,,,,7.22,,92.05,HAP,-2.11567,0.100394,0.00267607,1.21857 kka2_1:8_E3F,kka2_1:8_3,Kka2,kka2_1:8,P00552,1.21857,NO,3,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.199,-3.772,1.573,,,,,,,7.22,,92.05,HAP,-2.11567,0.100394,0.00267607,1.21857 kka2_1:4_A229T,kka2_1:4_229,Kka2,kka2_1:4,P00552,1.21859,NO,229,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.739,-2.302,0.563,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.168804,0.00942138,1.21859 beta-lactamase_0_E102K,beta-lactamase_0_102,TEM-1,beta-lactamase_0,P62593,1.21866,NO,102,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.118,-2.64,0.522,,0.722,S,B,1.04,1.82,4.773,,73.08,HAH,-1.581,0.0500837,0.00486633,1.21866 kka2_1:8_M178W,kka2_1:8_178,Kka2,kka2_1:8,P00552,1.21871,NO,178,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-3.206,-5.507,2.301,,0.554,,b,1.59,0.68,13.268,13.268,71.59,BHO,-2.154,0.100394,0.00717253,1.21871 kka2_1:8_M178W,kka2_1:8_178,Kka2,kka2_1:8,P00552,1.21871,NO,178,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-3.206,-5.507,2.301,,0.554,,b,1.59,0.68,13.268,13.268,71.59,BHO,-2.154,0.100394,0.00717253,1.21871 kka2_1:2_Q42H,kka2_1:2_42,Kka2,kka2_1:2,P00552,1.21874,NO,42,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.907,-3.3,0.393,,1.044,T,B,0.64,-0.8,2.792,,71.59,HPO,-2.12433,0.295029,0.00679212,1.21874 kka2_1:8_A108L,kka2_1:8_108,Kka2,kka2_1:8,P00552,1.21886,NO,108,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.061,-2.851,0.79,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.100394,0.00751209,1.21886 kka2_1:8_A108L,kka2_1:8_108,Kka2,kka2_1:8,P00552,1.21886,NO,108,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.061,-2.851,0.79,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.100394,0.00751209,1.21886 beta-lactamase_0_I258L,beta-lactamase_0_258,TEM-1,beta-lactamase_0,P62593,1.21887,NO,258,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.0500837,0.007931,1.21887 beta-lactamase_0_L191I,beta-lactamase_0_191,TEM-1,beta-lactamase_0,P62593,1.21888,NO,191,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.087,-3.028,1.941,,,H,A,0.55,0.09,12.255,12.255,63.29,BHH,-1.445,0.0500837,0.00263549,1.21888 kka2_1:8_G234N,kka2_1:8_234,Kka2,kka2_1:8,P00552,1.21896,NO,234,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-2.9,-3.105,0.205,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.100394,0.00984449,1.21896 kka2_1:8_G234N,kka2_1:8_234,Kka2,kka2_1:8,P00552,1.21896,NO,234,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-2.9,-3.105,0.205,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.100394,0.00984449,1.21896 beta-lactamase_0_D212H,beta-lactamase_0_212,TEM-1,beta-lactamase_0,P62593,1.219,NO,212,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.624,-4.56,2.936,,0.037,,b,0.75,-0.58,3.34,,74.48,HAB,-1.77667,0.0500837,0.00644302,1.219 beta-lactamase_0_K30M,beta-lactamase_0_30,TEM-1,beta-lactamase_0,P62593,1.21901,NO,30,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-2.307,-4.578,2.271,,0.142,H,A,2.34,-0.65,1.491,,93.01,HBH,-2.32833,0.0500837,0.00448593,1.21901 beta-lactamase_0_E238N,beta-lactamase_0_238,TEM-1,beta-lactamase_0,P62593,1.21905,NO,238,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.0500837,0.00743256,1.21905 kka2_1:8_L53S,kka2_1:8_53,Kka2,kka2_1:8,P00552,1.21913,NO,53,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-2.681,-2.891,0.21,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.100394,0.00671168,1.21913 kka2_1:8_L53S,kka2_1:8_53,Kka2,kka2_1:8,P00552,1.21913,NO,53,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-2.681,-2.891,0.21,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.100394,0.00671168,1.21913 beta-lactamase_0_E62F,beta-lactamase_0_62,TEM-1,beta-lactamase_0,P62593,1.21921,NO,62,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.193,-4.376,3.183,,0.342,S,B,1.04,-0.3,5.784,,73.08,AAB,-1.417,0.0500837,0.00264802,1.21921 kka2_1:4_D157C,kka2_1:4_157,Kka2,kka2_1:4,P00552,1.21932,NO,157,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.993,-5.181,4.188,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.168804,0.0042313,1.21932 kka2_1:8_I2C,kka2_1:8_2,Kka2,kka2_1:8,P00552,1.21936,NO,2,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.787,-4.477,2.69,,,,,,,,,71.59,HHA,-1.92433,0.100394,0.00246644,1.21936 kka2_1:8_I2C,kka2_1:8_2,Kka2,kka2_1:8,P00552,1.21936,NO,2,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.787,-4.477,2.69,,,,,,,,,71.59,HHA,-1.92433,0.100394,0.00246644,1.21936 kka2_1:8_E230T,kka2_1:8_230,Kka2,kka2_1:8,P00552,1.21938,NO,230,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.672,-3.072,0.4,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.100394,0.00920051,1.21938 kka2_1:8_E230T,kka2_1:8_230,Kka2,kka2_1:8,P00552,1.21938,NO,230,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.672,-3.072,0.4,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.100394,0.00920051,1.21938 kka2_1:8_P76K,kka2_1:8_76,Kka2,kka2_1:8,P00552,1.21946,NO,76,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.449,-3.635,2.186,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.100394,0.00625685,1.21946 kka2_1:8_P76K,kka2_1:8_76,Kka2,kka2_1:8,P00552,1.21946,NO,76,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.449,-3.635,2.186,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.100394,0.00625685,1.21946 kka2_1:2_A129T,kka2_1:2_129,Kka2,kka2_1:2,P00552,1.2195,NO,129,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.656,-2.639,0.983,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.295029,0.00726862,1.2195 kka2_1:4_E169D,kka2_1:4_169,Kka2,kka2_1:4,P00552,1.21953,NO,169,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.996,-1.998,0.002,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.168804,0.00730086,1.21953 kka2_1:8_A35G,kka2_1:8_35,Kka2,kka2_1:8,P00552,1.21962,NO,35,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.127,-2.532,0.405,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.100394,0.00630016,1.21962 kka2_1:8_A35G,kka2_1:8_35,Kka2,kka2_1:8,P00552,1.21962,NO,35,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.127,-2.532,0.405,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.100394,0.00630016,1.21962 kka2_1:4_P45S,kka2_1:4_45,Kka2,kka2_1:4,P00552,1.21968,NO,45,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.774,-2.464,0.69,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.168804,0.00590481,1.21968 kka2_1:2_D180T,kka2_1:2_180,Kka2,kka2_1:2,P00552,1.21975,NO,180,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.416,-3.001,0.585,,1.03,S,a,0.75,1.5,1.27,,71.59,OAO,-2.02933,0.295029,0.00756412,1.21975 kka2_1:8_H139I,kka2_1:8_139,Kka2,kka2_1:8,P00552,1.21991,NO,139,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-2.809,-3.326,0.517,,0.471,H,A,0.17,0.68,28.583,28.583,63.64,BBB,-2.22,0.100394,0.00734779,1.21991 kka2_1:8_H139I,kka2_1:8_139,Kka2,kka2_1:8,P00552,1.21991,NO,139,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-2.809,-3.326,0.517,,0.471,H,A,0.17,0.68,28.583,28.583,63.64,BBB,-2.22,0.100394,0.00734779,1.21991 kka2_1:4_K175H,kka2_1:4_175,Kka2,kka2_1:4,P00552,1.22003,NO,175,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-2.897,-3.28,0.383,,0.579,H,A,1.3,0.51,15.629,15.629,71.59,HBH,-1.82333,0.168804,0.00693093,1.22003 kka2_1:8_G6Y,kka2_1:8_6,Kka2,kka2_1:8,P00552,1.22037,NO,6,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.685,-4.17,2.485,,,,,,,,,71.59,AOH,-1.639,0.100394,0.00204693,1.22037 kka2_1:8_G6Y,kka2_1:8_6,Kka2,kka2_1:8,P00552,1.22037,NO,6,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.685,-4.17,2.485,,,,,,,,,71.59,AOH,-1.639,0.100394,0.00204693,1.22037 kka2_1:4_R258K,kka2_1:4_258,Kka2,kka2_1:4,P00552,1.22044,NO,258,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.626,-3.325,1.699,,0.316,H,A,1.2,-0.85,2.655,,53.03,HBH,-1.25933,0.168804,0.00983174,1.22044 kka2_1:4_G74H,kka2_1:4_74,Kka2,kka2_1:4,P00552,1.22048,NO,74,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.18,-4.623,3.443,,0.621,T,l,0.75,0.2,1.032,,64.39,POH,-1.91667,0.168804,0.00587035,1.22048 kka2_1:2_D101N,kka2_1:2_101,Kka2,kka2_1:2,P00552,1.22051,NO,101,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.028,-2.135,1.107,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.295029,0.00423361,1.22051 kka2_1:4_L39I,kka2_1:4_39,Kka2,kka2_1:4,P00552,1.22063,NO,39,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.223,-2.15,0.927,,,E,B,0.55,-1.21,1.998,,71.59,BHP,-1.69167,0.168804,0.00493618,1.22063 beta-lactamase_0_Q88Y,beta-lactamase_0_88,TEM-1,beta-lactamase_0,P62593,1.22068,NO,88,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.086,-4.349,2.263,,0.807,,B,0.64,2.03,0.4,,77.62,APH,-1.53433,0.0500837,0.00504167,1.22068 kka2_1:8_T225V,kka2_1:8_225,Kka2,kka2_1:8,P00552,1.22073,NO,225,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.393,-2.516,0.123,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.100394,0.0113598,1.22073 kka2_1:8_T225V,kka2_1:8_225,Kka2,kka2_1:8,P00552,1.22073,NO,225,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.393,-2.516,0.123,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.100394,0.0113598,1.22073 kka2_1:8_R18Y,kka2_1:8_18,Kka2,kka2_1:8,P00552,1.22077,NO,18,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.055,-3.413,1.358,,0.474,T,A,1.2,0.54,19.629,19.629,71.59,ABH,-1.821,0.100394,0.00724065,1.22077 kka2_1:8_R18Y,kka2_1:8_18,Kka2,kka2_1:8,P00552,1.22077,NO,18,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.055,-3.413,1.358,,0.474,T,A,1.2,0.54,19.629,19.629,71.59,ABH,-1.821,0.100394,0.00724065,1.22077 kka2_1:4_L47M,kka2_1:4_47,Kka2,kka2_1:4,P00552,1.22078,NO,47,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.265,-4.186,2.921,,0.139,E,B,0.55,-0.86,2.369,,63.26,HHH,-1.77933,0.168804,0.00509386,1.22078 kka2_1:2_P45S,kka2_1:2_45,Kka2,kka2_1:2,P00552,1.22082,NO,45,P,S,PS,Special,Polar,6.3,5.68,-0.62,74,115,105,-10,112.7,89,-23.7,-1.774,-2.464,0.69,,0.669,,B,0.52,-0.76,4.882,,71.59,BOH,-2.152,0.295029,0.00590481,1.22082 kka2_1:8_V242A,kka2_1:8_242,Kka2,kka2_1:8,P00552,1.22088,NO,242,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-2.687,-2.142,-0.545,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.100394,0.0102575,1.22088 kka2_1:8_V242A,kka2_1:8_242,Kka2,kka2_1:8,P00552,1.22088,NO,242,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-2.687,-2.142,-0.545,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.100394,0.0102575,1.22088 beta-lactamase_0_I280E,beta-lactamase_0_280,TEM-1,beta-lactamase_0,P62593,1.2209,NO,280,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.0500837,0.0530888,1.2209 kka2_1:4_H8C,kka2_1:4_8,Kka2,kka2_1:4,P00552,1.22091,NO,8,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-2.759,-2.768,0.009,,,,,,,,,71.59,HBH,-2.25467,0.168804,0.00256422,1.22091 kka2_1:8_D5R,kka2_1:8_5,Kka2,kka2_1:8,P00552,1.22093,NO,5,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.306,-3.57,2.264,,,,,,,1.147,,71.59,PAO,-1.784,0.100394,0.00222864,1.22093 kka2_1:8_D5R,kka2_1:8_5,Kka2,kka2_1:8,P00552,1.22093,NO,5,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.306,-3.57,2.264,,,,,,,1.147,,71.59,PAO,-1.784,0.100394,0.00222864,1.22093 kka2_1:2_V80P,kka2_1:2_80,Kka2,kka2_1:2,P00552,1.22101,NO,80,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.144,-2.863,1.719,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.295029,0.00488211,1.22101 kka2_1:8_A108Q,kka2_1:8_108,Kka2,kka2_1:8,P00552,1.22104,NO,108,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.061,-3.285,1.224,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.100394,0.00751209,1.22104 kka2_1:8_A108Q,kka2_1:8_108,Kka2,kka2_1:8,P00552,1.22104,NO,108,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.061,-3.285,1.224,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.100394,0.00751209,1.22104 kka2_1:2_E17S,kka2_1:2_17,Kka2,kka2_1:2,P00552,1.22105,NO,17,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.154,-2.653,0.499,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.295029,0.00688738,1.22105 beta-lactamase_0_R189H,beta-lactamase_0_189,TEM-1,beta-lactamase_0,P62593,1.22107,NO,189,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.844,-2.544,0.7,,0.278,H,A,1.2,1.01,12.11,12.11,72.73,HBB,-1.668,0.0500837,0.0050699,1.22107 kka2_1:2_I29V,kka2_1:2_29,Kka2,kka2_1:2,P00552,1.22128,NO,29,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.692,-2.359,0.667,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.295029,0.00619521,1.22128 kka2_1:8_L193F,kka2_1:8_193,Kka2,kka2_1:8,P00552,1.22128,NO,193,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.983,-3.816,2.833,,,G,A,1.59,-1.03,2.234,,65.53,OHO,-0.965333,0.100394,0.00480179,1.22128 kka2_1:8_L193F,kka2_1:8_193,Kka2,kka2_1:8,P00552,1.22128,NO,193,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.983,-3.816,2.833,,,G,A,1.59,-1.03,2.234,,65.53,OHO,-0.965333,0.100394,0.00480179,1.22128 kka2_1:2_L60I,kka2_1:2_60,Kka2,kka2_1:2,P00552,1.22136,NO,60,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.997,-2.513,1.516,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.295029,0.00262176,1.22136 kka2_1:8_E86D,kka2_1:8_86,Kka2,kka2_1:8,P00552,1.22161,NO,86,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.86,-1.985,0.125,,0.369,,B,1.52,1.92,,,63.26,PAH,-1.98067,0.100394,0.00642858,1.22161 kka2_1:8_E86D,kka2_1:8_86,Kka2,kka2_1:8,P00552,1.22161,NO,86,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.86,-1.985,0.125,,0.369,,B,1.52,1.92,,,63.26,PAH,-1.98067,0.100394,0.00642858,1.22161 beta-lactamase_0_F228G,beta-lactamase_0_228,TEM-1,beta-lactamase_0,P62593,1.22165,NO,228,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-2.342,-3.572,1.23,,0.154,E,B,0.58,-0.42,15.504,15.504,63.29,HHH,-1.53033,0.0500837,0.0046669,1.22165 kka2_1:8_R239A,kka2_1:8_239,Kka2,kka2_1:8,P00552,1.22166,NO,239,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.949,-2.185,-0.764,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.100394,0.00835326,1.22166 kka2_1:8_R239A,kka2_1:8_239,Kka2,kka2_1:8,P00552,1.22166,NO,239,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.949,-2.185,-0.764,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.100394,0.00835326,1.22166 kka2_1:4_P98K,kka2_1:4_98,Kka2,kka2_1:4,P00552,1.2217,NO,98,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.526,-2.937,1.411,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.168804,0.00622754,1.2217 kka2_1:2_D23R,kka2_1:2_23,Kka2,kka2_1:2,P00552,1.22172,NO,23,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.459,-2.183,-0.276,,0.695,E,B,0.75,-0.65,18.207,18.207,65.53,HAH,-1.94033,0.295029,0.007195,1.22172 kka2_1:8_A14Q,kka2_1:8_14,Kka2,kka2_1:8,P00552,1.22176,NO,14,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.837,-2.773,0.936,,0.728,G,A,0.46,0.7,,,71.59,HHH,-1.82567,0.100394,0.00706614,1.22176 kka2_1:8_A14Q,kka2_1:8_14,Kka2,kka2_1:8,P00552,1.22176,NO,14,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.837,-2.773,0.936,,0.728,G,A,0.46,0.7,,,71.59,HHH,-1.82567,0.100394,0.00706614,1.22176 kka2_1:8_G151D,kka2_1:8_151,Kka2,kka2_1:8,P00552,1.22186,NO,151,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.873,-2.683,1.81,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.100394,0.00339918,1.22186 kka2_1:8_G151D,kka2_1:8_151,Kka2,kka2_1:8,P00552,1.22186,NO,151,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.873,-2.683,1.81,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.100394,0.00339918,1.22186 kka2_1:8_A110L,kka2_1:8_110,Kka2,kka2_1:8,P00552,1.22194,NO,110,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.064,-2.329,0.265,,0.175,H,A,1.04,-1.19,11.413,11.413,71.59,OHA,-1.91867,0.100394,0.00759851,1.22194 kka2_1:8_A110L,kka2_1:8_110,Kka2,kka2_1:8,P00552,1.22194,NO,110,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.064,-2.329,0.265,,0.175,H,A,1.04,-1.19,11.413,11.413,71.59,OHA,-1.91867,0.100394,0.00759851,1.22194 kka2_1:8_G95N,kka2_1:8_95,Kka2,kka2_1:8,P00552,1.22206,NO,95,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-2.403,-2.561,0.158,,0.126,E,B,0.75,-0.74,7.774,,71.59,HOA,-2.198,0.100394,0.00743616,1.22206 kka2_1:8_G95N,kka2_1:8_95,Kka2,kka2_1:8,P00552,1.22206,NO,95,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-2.403,-2.561,0.158,,0.126,E,B,0.75,-0.74,7.774,,71.59,HOA,-2.198,0.100394,0.00743616,1.22206 kka2_1:4_S40M,kka2_1:4_40,Kka2,kka2_1:4,P00552,1.22211,NO,40,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.645,-4.831,2.186,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.168804,0.00693477,1.22211 kka2_1:8_E169T,kka2_1:8_169,Kka2,kka2_1:8,P00552,1.22212,NO,169,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.996,-2.692,0.696,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.100394,0.00730086,1.22212 kka2_1:8_E169T,kka2_1:8_169,Kka2,kka2_1:8,P00552,1.22212,NO,169,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.996,-2.692,0.696,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.100394,0.00730086,1.22212 kka2_1:8_R177L,kka2_1:8_177,Kka2,kka2_1:8,P00552,1.2223,NO,177,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.282,-2.255,-0.027,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.100394,0.00768224,1.2223 kka2_1:8_R177L,kka2_1:8_177,Kka2,kka2_1:8,P00552,1.2223,NO,177,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.282,-2.255,-0.027,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.100394,0.00768224,1.2223 kka2_1:8_R173N,kka2_1:8_173,Kka2,kka2_1:8,P00552,1.2224,NO,173,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.407,-3.101,0.694,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.100394,0.00784999,1.2224 kka2_1:8_R173N,kka2_1:8_173,Kka2,kka2_1:8,P00552,1.2224,NO,173,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.407,-3.101,0.694,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.100394,0.00784999,1.2224 kka2_1:4_A168N,kka2_1:4_168,Kka2,kka2_1:4,P00552,1.22243,NO,168,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.989,-3.164,1.175,,0.67,H,A,0.46,0.15,,,64.39,OHA,-2.12933,0.168804,0.00806773,1.22243 kka2_1:8_S40V,kka2_1:8_40,Kka2,kka2_1:8,P00552,1.22246,NO,40,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.645,-3.735,1.09,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.100394,0.00693477,1.22246 kka2_1:8_S40V,kka2_1:8_40,Kka2,kka2_1:8,P00552,1.22246,NO,40,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.645,-3.735,1.09,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.100394,0.00693477,1.22246 kka2_1:8_P249L,kka2_1:8_249,Kka2,kka2_1:8,P00552,1.22249,NO,249,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.867,-2.363,0.496,,0.406,.,B,0.52,-0.01,1.699,,92.05,HOA,-1.66867,0.100394,0.011045,1.22249 kka2_1:8_P249L,kka2_1:8_249,Kka2,kka2_1:8,P00552,1.22249,NO,249,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.867,-2.363,0.496,,0.406,.,B,0.52,-0.01,1.699,,92.05,HOA,-1.66867,0.100394,0.011045,1.22249 beta-lactamase_0_A182M,beta-lactamase_0_182,TEM-1,beta-lactamase_0,P62593,1.22251,NO,182,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.777,-4.709,2.932,,0.136,H,A,0.46,-0.66,10.765,10.765,93.01,OHH,-1.27367,0.0500837,0.00559099,1.22251 kka2_1:8_L165F,kka2_1:8_165,Kka2,kka2_1:8,P00552,1.22251,NO,165,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-2.453,-4.3,1.847,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.100394,0.00801161,1.22251 kka2_1:8_L165F,kka2_1:8_165,Kka2,kka2_1:8,P00552,1.22251,NO,165,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-2.453,-4.3,1.847,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.100394,0.00801161,1.22251 kka2_1:4_S40E,kka2_1:4_40,Kka2,kka2_1:4,P00552,1.22254,NO,40,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.645,-2.141,-0.504,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.168804,0.00693477,1.22254 kka2_1:4_P109A,kka2_1:4_109,Kka2,kka2_1:4,P00552,1.22264,NO,109,P,A,PA,Special,Hydrophobic,6.3,6,-0.3,27,115,89,-26,112.7,88.6,-24.1,-1.412,-1.957,0.545,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.168804,0.0070929,1.22264 beta-lactamase_0_H94K,beta-lactamase_0_94,TEM-1,beta-lactamase_0,P62593,1.22271,NO,94,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-2.5,-2.567,0.067,,0.776,,B,0.17,1.24,1.176,,77.62,HBH,-1.872,0.0500837,0.00389226,1.22271 kka2_1:2_A137M,kka2_1:2_137,Kka2,kka2_1:2,P00552,1.22272,NO,137,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.156,-4.232,2.076,,0.029,H,A,0.46,0.34,1.323,,63.26,PHB,-2.559,0.295029,0.00515054,1.22272 kka2_1:4_D238E,kka2_1:4_238,Kka2,kka2_1:4,P00552,1.22275,NO,238,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.83,-2.206,-0.624,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.168804,0.0113863,1.22275 kka2_1:8_R177M,kka2_1:8_177,Kka2,kka2_1:8,P00552,1.22278,NO,177,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.282,-3.296,1.014,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.100394,0.00768224,1.22278 kka2_1:8_R177M,kka2_1:8_177,Kka2,kka2_1:8,P00552,1.22278,NO,177,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.282,-3.296,1.014,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.100394,0.00768224,1.22278 beta-lactamase_0_I245V,beta-lactamase_0_245,TEM-1,beta-lactamase_0,P62593,1.22279,NO,245,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.0500837,0.00391032,1.22279 kka2_1:4_V198Q,kka2_1:4_198,Kka2,kka2_1:4,P00552,1.22279,NO,198,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.719,-4.058,2.339,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.168804,0.00835002,1.22279 kka2_1:1_G234V,kka2_1:1_234,Kka2,kka2_1:1,P00552,1.22284,NO,234,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-2.9,-2.894,-0.006,,0.494,H,A,0.29,-0.29,1.753,,71.59,OOA,-1.86767,0.520039,0.00984449,1.22284 kka2_1:4_D118E,kka2_1:4_118,Kka2,kka2_1:4,P00552,1.22297,NO,118,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.07,-2.401,0.331,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.168804,0.0067852,1.22297 beta-lactamase_0_E119C,beta-lactamase_0_119,TEM-1,beta-lactamase_0,P62593,1.22319,NO,119,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.412,-5.165,3.753,,0.358,H,A,1.04,0.51,3.396,,63.99,BAH,-1.623,0.0500837,0.00386966,1.22319 kka2_1:8_R44H,kka2_1:8_44,Kka2,kka2_1:8,P00552,1.22333,NO,44,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.062,-3.488,1.426,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.100394,0.00745043,1.22333 kka2_1:8_R44H,kka2_1:8_44,Kka2,kka2_1:8,P00552,1.22333,NO,44,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.062,-3.488,1.426,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.100394,0.00745043,1.22333 kka2_1:8_R177A,kka2_1:8_177,Kka2,kka2_1:8,P00552,1.22334,NO,177,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.282,-2.56,0.278,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.100394,0.00768224,1.22334 kka2_1:8_R177A,kka2_1:8_177,Kka2,kka2_1:8,P00552,1.22334,NO,177,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.282,-2.56,0.278,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.100394,0.00768224,1.22334 kka2_1:8_Q42C,kka2_1:8_42,Kka2,kka2_1:8,P00552,1.22345,NO,42,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.907,-5.227,2.32,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.100394,0.00679212,1.22345 kka2_1:8_Q42C,kka2_1:8_42,Kka2,kka2_1:8,P00552,1.22345,NO,42,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.907,-5.227,2.32,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.100394,0.00679212,1.22345 beta-lactamase_0_I93L,beta-lactamase_0_93,TEM-1,beta-lactamase_0,P62593,1.22346,NO,93,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.401,-2.05,0.649,,0.128,E,B,0.48,0.44,1.266,,67.83,BHB,-1.873,0.0500837,0.00527066,1.22346 beta-lactamase_0_E87N,beta-lactamase_0_87,TEM-1,beta-lactamase_0,P62593,1.22348,NO,87,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.421,-3.684,2.263,,0.048,,B,1.04,0.92,1.159,,64.69,PAP,-1.969,0.0500837,0.00337888,1.22348 kka2_1:4_D118Q,kka2_1:4_118,Kka2,kka2_1:4,P00552,1.22348,NO,118,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.07,-2.739,0.669,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.168804,0.0067852,1.22348 beta-lactamase_0_E61A,beta-lactamase_0_61,TEM-1,beta-lactamase_0,P62593,1.22351,NO,61,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.115,-2.668,0.553,,0.775,T,a,1.04,1.29,34.763,34.763,77.62,OAA,-1.92567,0.0500837,0.00440955,1.22351 kka2_1:2_A248L,kka2_1:2_248,Kka2,kka2_1:2,P00552,1.22356,NO,248,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.124,-3.034,0.91,,0.825,S,b,0.46,0.46,,,92.05,HHO,-2.15,0.295029,0.0125484,1.22356 kka2_1:8_K175V,kka2_1:8_175,Kka2,kka2_1:8,P00552,1.22367,NO,175,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-2.897,-2.802,-0.095,,0.579,H,A,2.34,0.51,15.316,15.316,71.59,HBH,-1.82333,0.100394,0.00693093,1.22367 kka2_1:8_K175V,kka2_1:8_175,Kka2,kka2_1:8,P00552,1.22367,NO,175,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-2.897,-2.802,-0.095,,0.579,H,A,2.34,0.51,15.316,15.316,71.59,HBH,-1.82333,0.100394,0.00693093,1.22367 kka2_1:8_E230F,kka2_1:8_230,Kka2,kka2_1:8,P00552,1.22369,NO,230,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.672,-3.006,0.334,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.100394,0.00920051,1.22369 kka2_1:8_E230F,kka2_1:8_230,Kka2,kka2_1:8,P00552,1.22369,NO,230,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.672,-3.006,0.334,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.100394,0.00920051,1.22369 kka2_1:8_L7N,kka2_1:8_7,Kka2,kka2_1:8,P00552,1.22381,NO,7,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.926,-3.49,1.564,,,,,,,,,71.59,OHB,-2.12333,0.100394,0.00269456,1.22381 kka2_1:8_L7N,kka2_1:8_7,Kka2,kka2_1:8,P00552,1.22381,NO,7,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.926,-3.49,1.564,,,,,,,,,71.59,OHB,-2.12333,0.100394,0.00269456,1.22381 kka2_1:4_A79M,kka2_1:4_79,Kka2,kka2_1:4,P00552,1.22398,NO,79,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.368,-3.668,1.3,,0.563,.,B,0.46,-0.43,2.291,,71.59,HHH,-1.752,0.168804,0.00664821,1.22398 kka2_1:4_A87D,kka2_1:4_87,Kka2,kka2_1:4,P00552,1.22413,NO,87,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.917,-2.332,0.415,,1.039,S,L,0.46,1.57,22.675,22.675,65.53,AHO,-1.822,0.168804,0.00791281,1.22413 kka2_1:2_G10Q,kka2_1:2_10,Kka2,kka2_1:2,P00552,1.22414,NO,10,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.921,-2.7,0.779,,,,,,,2.192,,71.59,HOP,-2.10733,0.295029,0.00289233,1.22414 kka2_1:8_G164W,kka2_1:8_164,Kka2,kka2_1:8,P00552,1.22416,NO,164,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.869,-5.307,4.438,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.100394,0.00442091,1.22416 kka2_1:8_G164W,kka2_1:8_164,Kka2,kka2_1:8,P00552,1.22416,NO,164,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-0.869,-5.307,4.438,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.100394,0.00442091,1.22416 beta-lactamase_0_R118S,beta-lactamase_0_118,TEM-1,beta-lactamase_0,P62593,1.22422,NO,118,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.413,-2.394,-0.019,,0.457,H,A,1.2,1.39,3.961,,77.62,HBA,-1.785,0.0500837,0.00538794,1.22422 kka2_1:8_A9P,kka2_1:8_9,Kka2,kka2_1:8,P00552,1.22422,NO,9,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.079,-2.571,0.492,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.100394,0.00273264,1.22422 kka2_1:8_A9P,kka2_1:8_9,Kka2,kka2_1:8,P00552,1.22422,NO,9,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.079,-2.571,0.492,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.100394,0.00273264,1.22422 kka2_1:4_G74T,kka2_1:4_74,Kka2,kka2_1:4,P00552,1.22433,NO,74,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.18,-3.624,2.444,,0.621,T,l,0.75,0.2,1.032,,64.39,POH,-1.91667,0.168804,0.00587035,1.22433 kka2_1:8_I254C,kka2_1:8_254,Kka2,kka2_1:8,P00552,1.22438,NO,254,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.933,-4.856,2.923,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.100394,0.0132375,1.22438 kka2_1:8_I254C,kka2_1:8_254,Kka2,kka2_1:8,P00552,1.22438,NO,254,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.933,-4.856,2.923,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.100394,0.0132375,1.22438 beta-lactamase_0_D99L,beta-lactamase_0_99,TEM-1,beta-lactamase_0,P62593,1.22441,NO,99,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.191,-3.588,2.397,,0.402,G,A,0.75,0.36,0.374,,64.69,PAH,-1.794,0.0500837,0.00305446,1.22441 kka2_1:4_Q42N,kka2_1:4_42,Kka2,kka2_1:4,P00552,1.22447,NO,42,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.907,-2.98,0.073,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.168804,0.00679212,1.22447 beta-lactamase_0_T138M,beta-lactamase_0_138,TEM-1,beta-lactamase_0,P62593,1.22457,NO,138,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.506,-4.821,2.315,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.0500837,0.00487868,1.22457 WW_domain_V171H,WW_domain_171,Yap65,WW_domain,P46937,1.22463,NO,171,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.547,-4.745,3.198,,,,,,,3.459,,70.24,AHO,-1.265,0.153962,0.00184125,1.22463 kka2_1:1_S251L,kka2_1:1_251,Kka2,kka2_1:1,P00552,1.22467,NO,251,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.636,-2.87,0.234,,0.712,H,A,0.27,-0.25,1.356,,71.59,APP,-2.09367,0.520039,0.0138916,1.22467 kka2_1:8_A229T,kka2_1:8_229,Kka2,kka2_1:8,P00552,1.22468,NO,229,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.739,-2.302,0.563,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.100394,0.00942138,1.22468 kka2_1:8_A229T,kka2_1:8_229,Kka2,kka2_1:8,P00552,1.22468,NO,229,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.739,-2.302,0.563,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.100394,0.00942138,1.22468 kka2_1:8_E231A,kka2_1:8_231,Kka2,kka2_1:8,P00552,1.22482,NO,231,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.002,-3.339,1.337,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.100394,0.00732383,1.22482 kka2_1:8_E231A,kka2_1:8_231,Kka2,kka2_1:8,P00552,1.22482,NO,231,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.002,-3.339,1.337,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.100394,0.00732383,1.22482 beta-lactamase_0_R275F,beta-lactamase_0_275,TEM-1,beta-lactamase_0,P62593,1.22494,NO,275,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.0500837,0.0141984,1.22494 beta-lactamase_0_K232E,beta-lactamase_0_232,TEM-1,beta-lactamase_0,P62593,1.22495,NO,232,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.012,-3.087,2.075,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.0500837,0.00313441,1.22495 kka2_1:4_Q219T,kka2_1:4_219,Kka2,kka2_1:4,P00552,1.22496,NO,219,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-0.93,-3.473,2.543,,0.088,H,A,0.64,-0.85,1.537,,50,HPA,-1.05167,0.168804,0.00237913,1.22496 WW_domain_Q186Y,WW_domain_186,Yap65,WW_domain,P46937,1.22501,NO,186,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-1.358,-3.714,2.356,4.88854,,,,,,,,,OPB,-1.207,0.153962,0.00161546,1.22501 kka2_1:4_A176T,kka2_1:4_176,Kka2,kka2_1:4,P00552,1.22506,NO,176,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.621,-2.528,0.907,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.168804,0.0083587,1.22506 kka2_1:4_L158V,kka2_1:4_158,Kka2,kka2_1:4,P00552,1.22508,NO,158,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.947,-2.604,0.657,,0.095,,B,1.59,0.77,7.588,,63.64,AHA,-1.25333,0.168804,0.00529068,1.22508 kka2_1:4_L81Q,kka2_1:4_81,Kka2,kka2_1:4,P00552,1.22513,NO,81,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.427,-3.189,1.762,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.168804,0.00805839,1.22513 beta-lactamase_0_P217V,beta-lactamase_0_217,TEM-1,beta-lactamase_0,P62593,1.22516,NO,217,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-2.062,-3.65,1.588,,0.496,I,A,0.52,-0.33,1.087,,74.48,OOH,-1.64333,0.0500837,0.00463211,1.22516 kka2_1:2_A25Q,kka2_1:2_25,Kka2,kka2_1:2,P00552,1.22518,NO,25,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.496,-2.581,0.085,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.295029,0.00595636,1.22518 beta-lactamase_0_I93V,beta-lactamase_0_93,TEM-1,beta-lactamase_0,P62593,1.22528,NO,93,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.401,-1.692,0.291,,0.128,E,B,0.48,0.44,1.266,,67.83,BHB,-1.873,0.0500837,0.00527066,1.22528 kka2_1:8_A35L,kka2_1:8_35,Kka2,kka2_1:8,P00552,1.2253,NO,35,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.127,-3.045,0.918,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.100394,0.00630016,1.2253 kka2_1:8_A35L,kka2_1:8_35,Kka2,kka2_1:8,P00552,1.2253,NO,35,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.127,-3.045,0.918,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.100394,0.00630016,1.2253 kka2_1:2_T72Q,kka2_1:2_72,Kka2,kka2_1:2,P00552,1.22537,NO,72,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.38,-2.662,0.282,,0.784,H,A,0.82,0.29,6.463,,65.53,HPP,-2.238,0.295029,0.00750756,1.22537 beta-lactamase_0_L120E,beta-lactamase_0_120,TEM-1,beta-lactamase_0,P62593,1.22539,NO,120,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.044,-3.83,2.786,,,H,A,0.55,-1.13,1.2,,64.69,AHO,-1.13633,0.0500837,0.00143563,1.22539 WW_domain_M179E,WW_domain_179,Yap65,WW_domain,P46937,1.22548,NO,179,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.541,-3.442,1.901,6.54704,,,,,,,,,AHH,-1.31367,0.153962,0.00400164,1.22548 kka2_1:8_G6R,kka2_1:8_6,Kka2,kka2_1:8,P00552,1.2255,NO,6,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.685,-3.575,1.89,,,,,,,,,71.59,AOH,-1.639,0.100394,0.00204693,1.2255 kka2_1:8_G6R,kka2_1:8_6,Kka2,kka2_1:8,P00552,1.2255,NO,6,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.685,-3.575,1.89,,,,,,,,,71.59,AOH,-1.639,0.100394,0.00204693,1.2255 kka2_1:8_N200G,kka2_1:8_200,Kka2,kka2_1:8,P00552,1.22562,NO,200,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-2.446,-1.948,-0.498,,0.756,T,L,0.43,-0.08,2.528,,64.39,APO,-2.08,0.100394,0.00838549,1.22562 kka2_1:8_N200G,kka2_1:8_200,Kka2,kka2_1:8,P00552,1.22562,NO,200,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-2.446,-1.948,-0.498,,0.756,T,L,0.43,-0.08,2.528,,64.39,APO,-2.08,0.100394,0.00838549,1.22562 kka2_1:4_L53D,kka2_1:4_53,Kka2,kka2_1:4,P00552,1.2257,NO,53,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-2.681,-2.935,0.254,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.168804,0.00671168,1.2257 kka2_1:4_S204A,kka2_1:4_204,Kka2,kka2_1:4,P00552,1.22571,NO,204,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.353,-1.861,0.508,,0.144,E,A,0.27,-1.2,2.442,,65.53,HPO,-0.953333,0.168804,0.00881794,1.22571 kka2_1:4_Q42P,kka2_1:4_42,Kka2,kka2_1:4,P00552,1.22573,NO,42,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.907,-2.271,-0.636,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.168804,0.00679212,1.22573 kka2_1:4_Q163N,kka2_1:4_163,Kka2,kka2_1:4,P00552,1.22584,NO,163,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.162,-3.939,1.777,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.168804,0.00719507,1.22584 kka2_1:2_D127N,kka2_1:2_127,Kka2,kka2_1:2,P00552,1.22607,NO,127,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.364,-3.671,2.307,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.295029,0.00660501,1.22607 kka2_1:4_V198C,kka2_1:4_198,Kka2,kka2_1:4,P00552,1.22618,NO,198,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.719,-4.752,3.033,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.168804,0.00835002,1.22618 kka2_1:2_V83A,kka2_1:2_83,Kka2,kka2_1:2,P00552,1.22619,NO,83,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-2.567,-2.453,-0.114,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.295029,0.00650486,1.22619 kka2_1:8_L47C,kka2_1:8_47,Kka2,kka2_1:8,P00552,1.2262,NO,47,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.265,-4.875,3.61,,0.139,E,B,1.59,-0.86,5.086,,63.26,HHH,-1.77933,0.100394,0.00509386,1.2262 kka2_1:8_L47C,kka2_1:8_47,Kka2,kka2_1:8,P00552,1.2262,NO,47,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.265,-4.875,3.61,,0.139,E,B,1.59,-0.86,5.086,,63.26,HHH,-1.77933,0.100394,0.00509386,1.2262 beta-lactamase_0_R159N,beta-lactamase_0_159,TEM-1,beta-lactamase_0,P62593,1.22629,NO,159,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-0.94,-3.445,2.505,,0.316,,B,1.2,-0.55,1.426,,64.34,PBH,-1.011,0.0500837,0.00108472,1.22629 kka2_1:8_A110D,kka2_1:8_110,Kka2,kka2_1:8,P00552,1.22639,NO,110,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.064,-2.796,0.732,,0.175,H,A,1.04,-1.19,11.413,11.413,71.59,OHA,-1.91867,0.100394,0.00759851,1.22639 kka2_1:8_A110D,kka2_1:8_110,Kka2,kka2_1:8,P00552,1.22639,NO,110,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.064,-2.796,0.732,,0.175,H,A,1.04,-1.19,11.413,11.413,71.59,OHA,-1.91867,0.100394,0.00759851,1.22639 kka2_1:2_A248K,kka2_1:2_248,Kka2,kka2_1:2,P00552,1.22641,NO,248,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.124,-2.875,0.751,,0.825,S,b,0.46,0.46,,,92.05,HHO,-2.15,0.295029,0.0125484,1.22641 kka2_1:4_G10N,kka2_1:4_10,Kka2,kka2_1:4,P00552,1.22658,NO,10,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.921,-2.575,0.654,,,,,,,1.862,,71.59,HOP,-2.10733,0.168804,0.00289233,1.22658 kka2_1:8_E235D,kka2_1:8_235,Kka2,kka2_1:8,P00552,1.22662,NO,235,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.955,-2.602,0.647,,0.631,H,A,1.52,0.12,,,65.53,OAH,-2.07267,0.100394,0.0102806,1.22662 kka2_1:8_E235D,kka2_1:8_235,Kka2,kka2_1:8,P00552,1.22662,NO,235,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.955,-2.602,0.647,,0.631,H,A,1.52,0.12,,,65.53,OAH,-2.07267,0.100394,0.0102806,1.22662 beta-lactamase_0_K232R,beta-lactamase_0_232,TEM-1,beta-lactamase_0,P62593,1.22663,NO,232,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-1.012,-1.888,0.876,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.0500837,0.00313441,1.22663 beta-lactamase_0_E166H,beta-lactamase_0_166,TEM-1,beta-lactamase_0,P62593,1.22673,NO,166,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.756,-4.668,2.912,,0.508,G,A,1.04,1.05,17.227,17.227,73.08,OAH,-1.42233,0.0500837,0.00512989,1.22673 kka2_1:8_G234D,kka2_1:8_234,Kka2,kka2_1:8,P00552,1.22674,NO,234,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-2.9,-2.299,-0.601,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.100394,0.00984449,1.22674 kka2_1:8_G234D,kka2_1:8_234,Kka2,kka2_1:8,P00552,1.22674,NO,234,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-2.9,-2.299,-0.601,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.100394,0.00984449,1.22674 kka2_1:8_A172N,kka2_1:8_172,Kka2,kka2_1:8,P00552,1.22676,NO,172,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.757,-3.17,1.413,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.100394,0.0079265,1.22676 kka2_1:8_A172N,kka2_1:8_172,Kka2,kka2_1:8,P00552,1.22676,NO,172,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.757,-3.17,1.413,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.100394,0.0079265,1.22676 kka2_1:2_D5E,kka2_1:2_5,Kka2,kka2_1:2,P00552,1.22687,NO,5,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.306,-1.813,0.507,,,,,,,,,71.59,PAO,-1.784,0.295029,0.00222864,1.22687 kka2_1:4_A14G,kka2_1:4_14,Kka2,kka2_1:4,P00552,1.2269,NO,14,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.837,-2.323,0.486,,0.728,G,A,0.46,0.7,0.36,,71.59,HHH,-1.82567,0.168804,0.00706614,1.2269 kka2_1:8_D5T,kka2_1:8_5,Kka2,kka2_1:8,P00552,1.2269,NO,5,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.306,-3.232,1.926,,,,,,,1.147,,71.59,PAO,-1.784,0.100394,0.00222864,1.2269 kka2_1:8_D5T,kka2_1:8_5,Kka2,kka2_1:8,P00552,1.2269,NO,5,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.306,-3.232,1.926,,,,,,,1.147,,71.59,PAO,-1.784,0.100394,0.00222864,1.2269 kka2_1:4_S11N,kka2_1:4_11,Kka2,kka2_1:4,P00552,1.22705,NO,11,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.322,-3.885,1.563,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.168804,0.00381691,1.22705 kka2_1:8_G74H,kka2_1:8_74,Kka2,kka2_1:8,P00552,1.22707,NO,74,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.18,-4.623,3.443,,0.621,T,l,0.29,0.2,2.014,,64.39,POH,-1.91667,0.100394,0.00587035,1.22707 kka2_1:8_G74H,kka2_1:8_74,Kka2,kka2_1:8,P00552,1.22707,NO,74,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.18,-4.623,3.443,,0.621,T,l,0.29,0.2,2.014,,64.39,POH,-1.91667,0.100394,0.00587035,1.22707 kka2_1:2_A255S,kka2_1:2_255,Kka2,kka2_1:2,P00552,1.22719,NO,255,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.715,-2.589,0.874,,0.466,H,A,0.46,-0.52,5.144,,65.53,HHH,-1.71267,0.295029,0.0126809,1.22719 beta-lactamase_0_F149W,beta-lactamase_0_149,TEM-1,beta-lactamase_0,P62593,1.22723,NO,149,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.299,-2.98,1.681,,0.195,H,A,0.58,0.11,3.518,,63.99,HHH,-1.46067,0.0500837,0.00418462,1.22723 kka2_1:4_G10Q,kka2_1:4_10,Kka2,kka2_1:4,P00552,1.22727,NO,10,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.921,-2.7,0.779,,,,,,,1.862,,71.59,HOP,-2.10733,0.168804,0.00289233,1.22727 kka2_1:8_S11A,kka2_1:8_11,Kka2,kka2_1:8,P00552,1.2274,NO,11,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.322,-2.34,0.018,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.100394,0.00381691,1.2274 kka2_1:8_S11A,kka2_1:8_11,Kka2,kka2_1:8,P00552,1.2274,NO,11,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.322,-2.34,0.018,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.100394,0.00381691,1.2274 beta-lactamase_0_E238P,beta-lactamase_0_238,TEM-1,beta-lactamase_0,P62593,1.22743,NO,238,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.0500837,0.00743256,1.22743 kka2_1:8_G21E,kka2_1:8_21,Kka2,kka2_1:8,P00552,1.22747,NO,21,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.368,-3.414,2.046,,0.586,T,l,0.29,-0.75,4.889,,71.59,HOH,-2.10167,0.100394,0.00709648,1.22747 kka2_1:8_G21E,kka2_1:8_21,Kka2,kka2_1:8,P00552,1.22747,NO,21,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.368,-3.414,2.046,,0.586,T,l,0.29,-0.75,4.889,,71.59,HOH,-2.10167,0.100394,0.00709648,1.22747 kka2_1:4_T187C,kka2_1:4_187,Kka2,kka2_1:4,P00552,1.22752,NO,187,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.273,-2.642,1.369,,0.007,E,B,0.22,-0.85,2.73,,52.27,HPB,-1.06567,0.168804,0.00693073,1.22752 kka2_1:4_A248E,kka2_1:4_248,Kka2,kka2_1:4,P00552,1.22755,NO,248,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.124,-2.197,0.073,,0.825,S,b,0.46,0.46,,,92.05,HHO,-2.15,0.168804,0.0125484,1.22755 kka2_1:8_E111H,kka2_1:8_111,Kka2,kka2_1:8,P00552,1.22758,NO,111,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.28,-3.298,1.018,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.100394,0.00746789,1.22758 kka2_1:8_E111H,kka2_1:8_111,Kka2,kka2_1:8,P00552,1.22758,NO,111,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.28,-3.298,1.018,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.100394,0.00746789,1.22758 kka2_1:4_A129M,kka2_1:4_129,Kka2,kka2_1:4,P00552,1.22769,NO,129,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.656,-4.824,3.168,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.168804,0.00726862,1.22769 kka2_1:4_P249L,kka2_1:4_249,Kka2,kka2_1:4,P00552,1.22771,NO,249,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.867,-2.363,0.496,,0.406,.,B,0.52,-0.01,,,92.05,HOA,-1.66867,0.168804,0.011045,1.22771 kka2_1:8_A129Q,kka2_1:8_129,Kka2,kka2_1:8,P00552,1.22771,NO,129,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.656,-3.989,2.333,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.100394,0.00726862,1.22771 kka2_1:8_A129Q,kka2_1:8_129,Kka2,kka2_1:8,P00552,1.22771,NO,129,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.656,-3.989,2.333,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.100394,0.00726862,1.22771 kka2_1:2_E235H,kka2_1:2_235,Kka2,kka2_1:2,P00552,1.22783,NO,235,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.955,-4.699,2.744,,0.631,H,A,1.04,0.12,26.048,26.048,65.53,OAH,-2.07267,0.295029,0.0102806,1.22783 kka2_1:8_Q163C,kka2_1:8_163,Kka2,kka2_1:8,P00552,1.22801,NO,163,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.162,-5.049,2.887,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.100394,0.00719507,1.22801 kka2_1:8_Q163C,kka2_1:8_163,Kka2,kka2_1:8,P00552,1.22801,NO,163,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.162,-5.049,2.887,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.100394,0.00719507,1.22801 kka2_1:8_Q27N,kka2_1:8_27,Kka2,kka2_1:8,P00552,1.22801,NO,27,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-1.659,-3.726,2.067,,0.608,.,A,0.64,0.71,3.919,,65.53,PPP,-1.90733,0.100394,0.00595365,1.22801 kka2_1:8_Q27N,kka2_1:8_27,Kka2,kka2_1:8,P00552,1.22801,NO,27,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-1.659,-3.726,2.067,,0.608,.,A,0.64,0.71,3.919,,65.53,PPP,-1.90733,0.100394,0.00595365,1.22801 kka2_1:8_R202E,kka2_1:8_202,Kka2,kka2_1:8,P00552,1.22801,NO,202,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.761,-2.596,0.835,,0.607,E,B,1.2,0.48,1.409,,52.27,OBH,-1.41067,0.100394,0.00696498,1.22801 kka2_1:8_R202E,kka2_1:8_202,Kka2,kka2_1:8,P00552,1.22801,NO,202,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.761,-2.596,0.835,,0.607,E,B,1.2,0.48,1.409,,52.27,OBH,-1.41067,0.100394,0.00696498,1.22801 kka2_1:2_T146K,kka2_1:2_146,Kka2,kka2_1:2,P00552,1.22831,NO,146,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.978,-2.607,-0.371,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.295029,0.00606474,1.22831 kka2_1:4_A41Y,kka2_1:4_41,Kka2,kka2_1:4,P00552,1.22832,NO,41,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.879,-4.263,2.384,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.168804,0.00543332,1.22832 beta-lactamase_0_K232D,beta-lactamase_0_232,TEM-1,beta-lactamase_0,P62593,1.22835,NO,232,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.012,-3.566,2.554,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.0500837,0.00313441,1.22835 kka2_1:8_E160R,kka2_1:8_160,Kka2,kka2_1:8,P00552,1.22836,NO,160,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.683,-3.847,2.164,,0.989,G,A,1.04,2.28,2.164,,71.59,AAA,-1.36133,0.100394,0.00935762,1.22836 kka2_1:8_E160R,kka2_1:8_160,Kka2,kka2_1:8,P00552,1.22836,NO,160,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.683,-3.847,2.164,,0.989,G,A,1.04,2.28,2.164,,71.59,AAA,-1.36133,0.100394,0.00935762,1.22836 kka2_1:2_G181A,kka2_1:2_181,Kka2,kka2_1:2,P00552,1.22855,NO,181,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-2.698,-2.631,-0.067,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.295029,0.00728319,1.22855 kka2_1:2_H8D,kka2_1:2_8,Kka2,kka2_1:2,P00552,1.22859,NO,8,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-2.759,-3.533,0.774,,,,,,,,,71.59,HBH,-2.25467,0.295029,0.00256422,1.22859 kka2_1:8_G6Q,kka2_1:8_6,Kka2,kka2_1:8,P00552,1.2286,NO,6,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.685,-3.809,2.124,,,,,,,,,71.59,AOH,-1.639,0.100394,0.00204693,1.2286 kka2_1:8_G6Q,kka2_1:8_6,Kka2,kka2_1:8,P00552,1.2286,NO,6,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.685,-3.809,2.124,,,,,,,,,71.59,AOH,-1.639,0.100394,0.00204693,1.2286 kka2_1:2_V75M,kka2_1:2_75,Kka2,kka2_1:2,P00552,1.22864,NO,75,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-2.06,-2.759,0.699,,0.042,.,B,0.44,-0.2,2.815,,71.59,OHO,-1.563,0.295029,0.00693733,1.22864 kka2_1:8_I2D,kka2_1:8_2,Kka2,kka2_1:8,P00552,1.22874,NO,2,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.787,-3.608,1.821,,,,,,,,,71.59,HHA,-1.92433,0.100394,0.00246644,1.22874 kka2_1:8_I2D,kka2_1:8_2,Kka2,kka2_1:8,P00552,1.22874,NO,2,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.787,-3.608,1.821,,,,,,,,,71.59,HHA,-1.92433,0.100394,0.00246644,1.22874 beta-lactamase_0_F58I,beta-lactamase_0_58,TEM-1,beta-lactamase_0,P62593,1.22878,NO,58,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-2.914,-3.971,1.057,,0.266,E,B,0.58,-0.07,24.637,24.637,77.62,PHB,-2.059,0.0500837,0.00523369,1.22878 kka2_1:8_R177D,kka2_1:8_177,Kka2,kka2_1:8,P00552,1.22884,NO,177,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.282,-3.754,1.472,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.100394,0.00768224,1.22884 kka2_1:8_R177D,kka2_1:8_177,Kka2,kka2_1:8,P00552,1.22884,NO,177,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.282,-3.754,1.472,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.100394,0.00768224,1.22884 kka2_1:4_A150R,kka2_1:4_150,Kka2,kka2_1:4,P00552,1.22898,NO,150,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-0.949,-3.769,2.82,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.168804,0.0045009,1.22898 kka2_1:2_A14V,kka2_1:2_14,Kka2,kka2_1:2,P00552,1.22913,NO,14,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.837,-2.963,1.126,,0.728,G,A,0.46,0.7,0.36,,71.59,HHH,-1.82567,0.295029,0.00706614,1.22913 kka2_1:4_G10R,kka2_1:4_10,Kka2,kka2_1:4,P00552,1.22916,NO,10,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.921,-2.648,0.727,,,,,,,1.862,,71.59,HOP,-2.10733,0.168804,0.00289233,1.22916 beta-lactamase_0_A230N,beta-lactamase_0_230,TEM-1,beta-lactamase_0,P62593,1.22918,NO,230,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.154,-3.731,2.577,,0.01,E,B,0.46,-1.17,2.179,,50,HHA,-1.079,0.0500837,0.00516841,1.22918 kka2_1:4_I2K,kka2_1:4_2,Kka2,kka2_1:4,P00552,1.22924,NO,2,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.787,-3.536,1.749,,,,,,,,,71.59,HHA,-1.92433,0.168804,0.00246644,1.22924 kka2_1:4_D23A,kka2_1:4_23,Kka2,kka2_1:4,P00552,1.22931,NO,23,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.459,-2.468,0.009,,0.695,E,B,0.75,-0.65,2.416,,65.53,HAH,-1.94033,0.168804,0.007195,1.22931 kka2_1:8_D82N,kka2_1:8_82,Kka2,kka2_1:8,P00552,1.22945,NO,82,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.946,-3.098,1.152,,0.341,E,b,0.29,0.52,7.463,,63.64,HAH,-1.98,0.100394,0.00637516,1.22945 kka2_1:8_D82N,kka2_1:8_82,Kka2,kka2_1:8,P00552,1.22945,NO,82,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.946,-3.098,1.152,,0.341,E,b,0.29,0.52,7.463,,63.64,HAH,-1.98,0.100394,0.00637516,1.22945 kka2_1:4_P179I,kka2_1:4_179,Kka2,kka2_1:4,P00552,1.22948,NO,179,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-0.974,-3.795,2.821,,0.113,,B,0.52,0.69,10.913,10.913,56.06,HOA,-2.19867,0.168804,0.00298346,1.22948 kka2_1:8_V46M,kka2_1:8_46,Kka2,kka2_1:8,P00552,1.22958,NO,46,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-2.62,-3.643,1.023,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.100394,0.00631301,1.22958 kka2_1:8_V46M,kka2_1:8_46,Kka2,kka2_1:8,P00552,1.22958,NO,46,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-2.62,-3.643,1.023,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.100394,0.00631301,1.22958 kka2_1:4_G151E,kka2_1:4_151,Kka2,kka2_1:4,P00552,1.22959,NO,151,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.873,-3.557,2.684,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.168804,0.00339918,1.22959 kka2_1:2_S68N,kka2_1:2_68,Kka2,kka2_1:2,P00552,1.22975,NO,68,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.623,-3.062,0.439,,0.48,H,A,0.27,-0.1,2.655,,71.59,HPH,-1.40767,0.295029,0.00608265,1.22975 kka2_1:4_Q4E,kka2_1:4_4,Kka2,kka2_1:4,P00552,1.22992,NO,4,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.361,-3.058,0.697,,,,,,,2.026,,71.59,APA,-1.95533,0.168804,0.00239179,1.22992 kka2_1:4_E161C,kka2_1:4_161,Kka2,kka2_1:4,P00552,1.22994,NO,161,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.581,-5.043,3.462,,0.829,G,A,1.52,2.24,1.612,,92.05,AAB,-1.861,0.168804,0.00760103,1.22994 kka2_1:8_F20C,kka2_1:8_20,Kka2,kka2_1:8,P00552,1.23008,NO,20,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-3.354,-5.001,1.647,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.100394,0.00701744,1.23008 kka2_1:8_F20C,kka2_1:8_20,Kka2,kka2_1:8,P00552,1.23008,NO,20,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-3.354,-5.001,1.647,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.100394,0.00701744,1.23008 kka2_1:4_Q252C,kka2_1:4_252,Kka2,kka2_1:4,P00552,1.23009,NO,252,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.63,-5.184,2.554,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.168804,0.0121001,1.23009 kka2_1:4_R202V,kka2_1:4_202,Kka2,kka2_1:4,P00552,1.2301,NO,202,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.761,-3.107,1.346,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.168804,0.00696498,1.2301 kka2_1:2_A172H,kka2_1:2_172,Kka2,kka2_1:2,P00552,1.23011,NO,172,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.757,-4.807,3.05,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.295029,0.0079265,1.23011 kka2_1:8_A166H,kka2_1:8_166,Kka2,kka2_1:8,P00552,1.23032,NO,166,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.407,-4.764,2.357,,0.534,,B,1.04,1.03,13.995,13.995,71.59,HHO,-2.421,0.100394,0.00799912,1.23032 kka2_1:8_A166H,kka2_1:8_166,Kka2,kka2_1:8,P00552,1.23032,NO,166,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.407,-4.764,2.357,,0.534,,B,1.04,1.03,13.995,13.995,71.59,HHO,-2.421,0.100394,0.00799912,1.23032 kka2_1:4_K175E,kka2_1:4_175,Kka2,kka2_1:4,P00552,1.23033,NO,175,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-2.897,-2.454,-0.443,,0.579,H,A,1.3,0.51,15.629,15.629,71.59,HBH,-1.82333,0.168804,0.00693093,1.23033 beta-lactamase_0_I244C,beta-lactamase_0_244,TEM-1,beta-lactamase_0,P62593,1.23037,NO,244,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.555,-4.712,3.157,,,E,B,0.48,-0.84,1.241,,77.62,OHH,-1.385,0.0500837,0.00605379,1.23037 kka2_1:1_A35Q,kka2_1:1_35,Kka2,kka2_1:1,P00552,1.23043,NO,35,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.127,-3.255,1.128,,0.107,E,B,0.46,1.05,8.405,8.405,71.59,HHH,-1.31767,0.520039,0.00630016,1.23043 kka2_1:4_W15F,kka2_1:4_15,Kka2,kka2_1:4,P00552,1.23046,NO,15,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-1.392,-2.518,1.126,,0.01,G,A,0.47,0.15,0.943,,52.27,HHH,-2.10533,0.168804,0.00585505,1.23046 kka2_1:4_Q26L,kka2_1:4_26,Kka2,kka2_1:4,P00552,1.23049,NO,26,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.18,-2.769,0.589,,0.448,E,B,0.4,0.44,5.022,,92.05,HPP,-2.11167,0.168804,0.00708962,1.23049 kka2_1:4_A25F,kka2_1:4_25,Kka2,kka2_1:4,P00552,1.23054,NO,25,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.496,-4.408,1.912,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.168804,0.00595636,1.23054 kka2_1:4_Q26E,kka2_1:4_26,Kka2,kka2_1:4,P00552,1.23068,NO,26,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.18,-2.898,0.718,,0.448,E,B,0.4,0.44,5.022,,92.05,HPP,-2.11167,0.168804,0.00708962,1.23068 kka2_1:4_V49I,kka2_1:4_49,Kka2,kka2_1:4,P00552,1.2307,NO,49,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.614,-2.255,0.641,,,E,B,0.44,-0.77,1.233,,64.39,HHB,-1.3,0.168804,0.00615685,1.2307 kka2_1:8_S251L,kka2_1:8_251,Kka2,kka2_1:8,P00552,1.23073,NO,251,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.636,-2.87,0.234,,0.712,H,A,0.27,-0.25,,,71.59,APP,-2.09367,0.100394,0.0138916,1.23073 kka2_1:8_S251L,kka2_1:8_251,Kka2,kka2_1:8,P00552,1.23073,NO,251,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.636,-2.87,0.234,,0.712,H,A,0.27,-0.25,,,71.59,APP,-2.09367,0.100394,0.0138916,1.23073 kka2_1:4_Q42L,kka2_1:4_42,Kka2,kka2_1:4,P00552,1.23074,NO,42,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.907,-2.953,0.046,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.168804,0.00679212,1.23074 beta-lactamase_0_I244A,beta-lactamase_0_244,TEM-1,beta-lactamase_0,P62593,1.23077,NO,244,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.555,-3.008,1.453,,,E,B,0.48,-0.84,1.241,,77.62,OHH,-1.385,0.0500837,0.00605379,1.23077 kka2_1:8_A255G,kka2_1:8_255,Kka2,kka2_1:8,P00552,1.23084,NO,255,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.715,-2.509,0.794,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.100394,0.0126809,1.23084 kka2_1:8_A255G,kka2_1:8_255,Kka2,kka2_1:8,P00552,1.23084,NO,255,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.715,-2.509,0.794,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.100394,0.0126809,1.23084 beta-lactamase_0_S80E,beta-lactamase_0_80,TEM-1,beta-lactamase_0,P62593,1.23085,NO,80,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.029,-2.666,0.637,,0.192,H,A,0.27,0.46,12.403,12.403,77.62,HPB,-1.44567,0.0500837,0.00565569,1.23085 kka2_1:4_A41G,kka2_1:4_41,Kka2,kka2_1:4,P00552,1.23107,NO,41,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.879,-2.32,0.441,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.168804,0.00543332,1.23107 kka2_1:4_R173K,kka2_1:4_173,Kka2,kka2_1:4,P00552,1.23115,NO,173,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.407,-2.916,0.509,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.168804,0.00784999,1.23115 beta-lactamase_0_R273D,beta-lactamase_0_273,TEM-1,beta-lactamase_0,P62593,1.23117,NO,273,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.314,-3.543,1.229,,0.564,H,A,1.2,1.57,20.248,20.248,73.78,ABP,-1.841,0.0500837,0.0077952,1.23117 kka2_1:2_D52H,kka2_1:2_52,Kka2,kka2_1:2,P00552,1.2312,NO,52,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.271,-4.302,2.031,,0.22,E,B,0.75,0.8,1.123,,71.59,PAH,-2.38367,0.295029,0.00175694,1.2312 kka2_1:8_G6S,kka2_1:8_6,Kka2,kka2_1:8,P00552,1.23121,NO,6,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.685,-3.143,1.458,,,,,,,,,71.59,AOH,-1.639,0.100394,0.00204693,1.23121 kka2_1:8_G6S,kka2_1:8_6,Kka2,kka2_1:8,P00552,1.23121,NO,6,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.685,-3.143,1.458,,,,,,,,,71.59,AOH,-1.639,0.100394,0.00204693,1.23121 kka2_1:4_P128V,kka2_1:4_128,Kka2,kka2_1:4,P00552,1.23134,NO,128,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.922,-2.023,0.101,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.168804,0.00774689,1.23134 kka2_1:4_N200R,kka2_1:4_200,Kka2,kka2_1:4,P00552,1.23135,NO,200,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-2.446,-3.001,0.555,,0.756,T,L,0.61,-0.08,1.746,,64.39,APO,-2.08,0.168804,0.00838549,1.23135 beta-lactamase_0_V106L,beta-lactamase_0_106,TEM-1,beta-lactamase_0,P62593,1.23139,NO,106,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.218,-2.154,0.936,,0.258,T,A,0.44,0.24,0.952,,72.73,OHP,-1.04933,0.0500837,0.00304168,1.23139 kka2_1:4_E160I,kka2_1:4_160,Kka2,kka2_1:4,P00552,1.2314,NO,160,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.683,-4.13,2.447,,0.989,G,A,1.04,2.28,2.531,,71.59,AAA,-1.36133,0.168804,0.00935762,1.2314 kka2_1:8_A248L,kka2_1:8_248,Kka2,kka2_1:8,P00552,1.2314,NO,248,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.124,-3.034,0.91,,0.825,S,b,1.04,0.46,11.329,11.329,92.05,HHO,-2.15,0.100394,0.0125484,1.2314 kka2_1:8_A248L,kka2_1:8_248,Kka2,kka2_1:8,P00552,1.2314,NO,248,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.124,-3.034,0.91,,0.825,S,b,1.04,0.46,11.329,11.329,92.05,HHO,-2.15,0.100394,0.0125484,1.2314 kka2_1:8_E160N,kka2_1:8_160,Kka2,kka2_1:8,P00552,1.23142,NO,160,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.683,-2.876,1.193,,0.989,G,A,1.04,2.28,2.164,,71.59,AAA,-1.36133,0.100394,0.00935762,1.23142 kka2_1:8_E160N,kka2_1:8_160,Kka2,kka2_1:8,P00552,1.23142,NO,160,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.683,-2.876,1.193,,0.989,G,A,1.04,2.28,2.164,,71.59,AAA,-1.36133,0.100394,0.00935762,1.23142 kka2_1:8_S251P,kka2_1:8_251,Kka2,kka2_1:8,P00552,1.23144,NO,251,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.636,-2.034,-0.602,,0.712,H,A,0.27,-0.25,,,71.59,APP,-2.09367,0.100394,0.0138916,1.23144 kka2_1:8_S251P,kka2_1:8_251,Kka2,kka2_1:8,P00552,1.23144,NO,251,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.636,-2.034,-0.602,,0.712,H,A,0.27,-0.25,,,71.59,APP,-2.09367,0.100394,0.0138916,1.23144 kka2_1:4_E142Q,kka2_1:4_142,Kka2,kka2_1:4,P00552,1.23157,NO,142,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.221,-3.009,0.788,,0.471,H,A,1.52,0.85,3.693,,65.53,HAB,-2.08033,0.168804,0.00748883,1.23157 kka2_1:4_D23C,kka2_1:4_23,Kka2,kka2_1:4,P00552,1.2316,NO,23,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.459,-3.701,1.242,,0.695,E,B,0.75,-0.65,2.416,,65.53,HAH,-1.94033,0.168804,0.007195,1.2316 kka2_1:8_V75E,kka2_1:8_75,Kka2,kka2_1:8,P00552,1.23165,NO,75,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-2.06,-3.835,1.775,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.100394,0.00693733,1.23165 kka2_1:8_V75E,kka2_1:8_75,Kka2,kka2_1:8,P00552,1.23165,NO,75,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-2.06,-3.835,1.775,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.100394,0.00693733,1.23165 beta-lactamase_0_S283L,beta-lactamase_0_283,TEM-1,beta-lactamase_0,P62593,1.23177,NO,283,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.0500837,0.0429138,1.23177 beta-lactamase_0_I280C,beta-lactamase_0_280,TEM-1,beta-lactamase_0,P62593,1.23182,NO,280,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.0500837,0.0530888,1.23182 kka2_1:8_L47Y,kka2_1:8_47,Kka2,kka2_1:8,P00552,1.23184,NO,47,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.265,-3.972,2.707,,0.139,E,B,1.59,-0.86,5.086,,63.26,HHH,-1.77933,0.100394,0.00509386,1.23184 kka2_1:8_L47Y,kka2_1:8_47,Kka2,kka2_1:8,P00552,1.23184,NO,47,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.265,-3.972,2.707,,0.139,E,B,1.59,-0.86,5.086,,63.26,HHH,-1.77933,0.100394,0.00509386,1.23184 kka2_1:8_G6L,kka2_1:8_6,Kka2,kka2_1:8,P00552,1.23185,NO,6,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.685,-3.363,1.678,,,,,,,,,71.59,AOH,-1.639,0.100394,0.00204693,1.23185 kka2_1:8_G6L,kka2_1:8_6,Kka2,kka2_1:8,P00552,1.23185,NO,6,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.685,-3.363,1.678,,,,,,,,,71.59,AOH,-1.639,0.100394,0.00204693,1.23185 kka2_1:4_P45D,kka2_1:4_45,Kka2,kka2_1:4,P00552,1.23195,NO,45,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.774,-3.026,1.252,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.168804,0.00590481,1.23195 kka2_1:4_A79I,kka2_1:4_79,Kka2,kka2_1:4,P00552,1.232,NO,79,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.368,-3.11,0.742,,0.563,.,B,0.46,-0.43,2.291,,71.59,HHH,-1.752,0.168804,0.00664821,1.232 kka2_1:4_T146C,kka2_1:4_146,Kka2,kka2_1:4,P00552,1.23222,NO,146,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.978,-5.009,2.031,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.168804,0.00606474,1.23222 beta-lactamase_0_H94W,beta-lactamase_0_94,TEM-1,beta-lactamase_0,P62593,1.23223,NO,94,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-2.5,-5.512,3.012,,0.776,,B,0.17,1.24,1.176,,77.62,HBH,-1.872,0.0500837,0.00389226,1.23223 kka2_1:8_Q42E,kka2_1:8_42,Kka2,kka2_1:8,P00552,1.23223,NO,42,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.907,-2.56,-0.347,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.100394,0.00679212,1.23223 kka2_1:8_Q42E,kka2_1:8_42,Kka2,kka2_1:8,P00552,1.23223,NO,42,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.907,-2.56,-0.347,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.100394,0.00679212,1.23223 kka2_1:8_L57H,kka2_1:8_57,Kka2,kka2_1:8,P00552,1.23231,NO,57,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.898,-2.613,0.715,,0.343,T,A,0.55,0.98,13.359,13.359,52.65,HHP,-2.20733,0.100394,0.00723769,1.23231 kka2_1:8_L57H,kka2_1:8_57,Kka2,kka2_1:8,P00552,1.23231,NO,57,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.898,-2.613,0.715,,0.343,T,A,0.55,0.98,13.359,13.359,52.65,HHP,-2.20733,0.100394,0.00723769,1.23231 beta-lactamase_0_S283W,beta-lactamase_0_283,TEM-1,beta-lactamase_0,P62593,1.23248,NO,283,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.0500837,0.0429138,1.23248 kka2_1:8_T225F,kka2_1:8_225,Kka2,kka2_1:8,P00552,1.23262,NO,225,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.393,-4.221,1.828,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.100394,0.0113598,1.23262 kka2_1:8_T225F,kka2_1:8_225,Kka2,kka2_1:8,P00552,1.23262,NO,225,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.393,-4.221,1.828,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.100394,0.0113598,1.23262 kka2_1:2_G43S,kka2_1:2_43,Kka2,kka2_1:2,P00552,1.23265,NO,43,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.587,-2.69,1.103,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.295029,0.0071925,1.23265 beta-lactamase_0_Q86F,beta-lactamase_0_86,TEM-1,beta-lactamase_0,P62593,1.23266,NO,86,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.4,-4.354,1.954,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.0500837,0.00450027,1.23266 kka2_1:2_A166R,kka2_1:2_166,Kka2,kka2_1:2,P00552,1.23274,NO,166,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.407,-3.179,0.772,,0.534,.,B,0.46,1.03,23.175,23.175,71.59,HHO,-2.421,0.295029,0.00799912,1.23274 kka2_1:8_V75L,kka2_1:8_75,Kka2,kka2_1:8,P00552,1.23274,NO,75,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-2.06,-1.581,-0.479,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.100394,0.00693733,1.23274 kka2_1:8_V75L,kka2_1:8_75,Kka2,kka2_1:8,P00552,1.23274,NO,75,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-2.06,-1.581,-0.479,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.100394,0.00693733,1.23274 kka2_1:8_Q163F,kka2_1:8_163,Kka2,kka2_1:8,P00552,1.23299,NO,163,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.162,-4.196,2.034,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.100394,0.00719507,1.23299 kka2_1:8_Q163F,kka2_1:8_163,Kka2,kka2_1:8,P00552,1.23299,NO,163,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.162,-4.196,2.034,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.100394,0.00719507,1.23299 kka2_1:2_A14H,kka2_1:2_14,Kka2,kka2_1:2,P00552,1.23305,NO,14,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.837,-4.803,2.966,,0.728,G,A,0.46,0.7,0.36,,71.59,HHH,-1.82567,0.295029,0.00706614,1.23305 kka2_1:2_E3H,kka2_1:2_3,Kka2,kka2_1:2,P00552,1.23308,NO,3,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.199,-4.214,2.015,,,,,,,7.22,,92.05,HAP,-2.11567,0.295029,0.00267607,1.23308 kka2_1:8_Q136G,kka2_1:8_136,Kka2,kka2_1:8,P00552,1.23317,NO,136,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-3.021,-2.521,-0.5,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.100394,0.00624149,1.23317 kka2_1:8_Q136G,kka2_1:8_136,Kka2,kka2_1:8,P00552,1.23317,NO,136,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-3.021,-2.521,-0.5,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.100394,0.00624149,1.23317 beta-lactamase_0_A278H,beta-lactamase_0_278,TEM-1,beta-lactamase_0,P62593,1.23321,NO,278,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.348,,,,0.015,H,A,0.48,-0.85,4.624,,63.29,HHA,-1.41833,0.0500837,0.0310297,1.23321 kka2_1:4_K138M,kka2_1:4_138,Kka2,kka2_1:4,P00552,1.23329,NO,138,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-2.5,-4.844,2.344,,0.594,H,A,1.3,0.98,21.267,21.267,71.59,HBB,-2.48833,0.168804,0.00628542,1.23329 kka2_1:4_A56L,kka2_1:4_56,Kka2,kka2_1:4,P00552,1.23342,NO,56,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.083,-2.797,0.714,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.168804,0.00717715,1.23342 kka2_1:8_D157Q,kka2_1:8_157,Kka2,kka2_1:8,P00552,1.23345,NO,157,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.993,-3.78,2.787,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.100394,0.0042313,1.23345 kka2_1:8_D157Q,kka2_1:8_157,Kka2,kka2_1:8,P00552,1.23345,NO,157,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.993,-3.78,2.787,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.100394,0.0042313,1.23345 kka2_1:4_A137W,kka2_1:4_137,Kka2,kka2_1:4,P00552,1.23352,NO,137,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.156,-2.974,0.818,,0.029,H,A,0.46,0.34,2.227,,63.26,PHB,-2.559,0.168804,0.00515054,1.23352 kka2_1:4_A35M,kka2_1:4_35,Kka2,kka2_1:4,P00552,1.23353,NO,35,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.127,-3.59,1.463,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.168804,0.00630016,1.23353 kka2_1:8_D33H,kka2_1:8_33,Kka2,kka2_1:8,P00552,1.23355,NO,33,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.186,-4.719,2.533,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.100394,0.00633568,1.23355 kka2_1:8_D33H,kka2_1:8_33,Kka2,kka2_1:8,P00552,1.23355,NO,33,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.186,-4.719,2.533,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.100394,0.00633568,1.23355 kka2_1:2_L53F,kka2_1:2_53,Kka2,kka2_1:2,P00552,1.23364,NO,53,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-2.681,-4.426,1.745,,0.569,E,B,0.55,0.8,19.536,19.536,71.59,AHP,-2.47433,0.295029,0.00671168,1.23364 kka2_1:8_I2F,kka2_1:8_2,Kka2,kka2_1:8,P00552,1.234,NO,2,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.787,-3.633,1.846,,,,,,,,,71.59,HHA,-1.92433,0.100394,0.00246644,1.234 kka2_1:8_I2F,kka2_1:8_2,Kka2,kka2_1:8,P00552,1.234,NO,2,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.787,-3.633,1.846,,,,,,,,,71.59,HHA,-1.92433,0.100394,0.00246644,1.234 kka2_1:8_A65V,kka2_1:8_65,Kka2,kka2_1:8,P00552,1.23414,NO,65,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.744,-2.657,0.913,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.100394,0.00709258,1.23414 kka2_1:8_A65V,kka2_1:8_65,Kka2,kka2_1:8,P00552,1.23414,NO,65,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.744,-2.657,0.913,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.100394,0.00709258,1.23414 kka2_1:2_A14T,kka2_1:2_14,Kka2,kka2_1:2,P00552,1.2342,NO,14,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.837,-2.286,0.449,,0.728,G,A,0.46,0.7,0.36,,71.59,HHH,-1.82567,0.295029,0.00706614,1.2342 gb1_A250W,gb1_250,gb1,gb1,P06654,1.23426,NO,250,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.713,-5.188,3.475,,,,,,,3.465,,45.54,HHP,-1.74867,0.177985,0.00332003,1.23426 kka2_1:8_E199L,kka2_1:8_199,Kka2,kka2_1:8,P00552,1.2344,NO,199,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.234,-3.058,0.824,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.100394,0.00854122,1.2344 kka2_1:8_E199L,kka2_1:8_199,Kka2,kka2_1:8,P00552,1.2344,NO,199,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.234,-3.058,0.824,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.100394,0.00854122,1.2344 kka2_1:4_L47V,kka2_1:4_47,Kka2,kka2_1:4,P00552,1.23456,NO,47,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.265,-2.308,1.043,,0.139,E,B,0.55,-0.86,2.369,,63.26,HHH,-1.77933,0.168804,0.00509386,1.23456 beta-lactamase_0_K190W,beta-lactamase_0_190,TEM-1,beta-lactamase_0,P62593,1.23457,NO,190,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.994,-5.522,3.528,,0.371,H,A,2.34,0.16,16.606,16.606,77.62,BBH,-1.64167,0.0500837,0.00574527,1.23457 kka2_1:4_V75E,kka2_1:4_75,Kka2,kka2_1:4,P00552,1.2346,NO,75,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-2.06,-3.835,1.775,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.168804,0.00693733,1.2346 kka2_1:4_D134F,kka2_1:4_134,Kka2,kka2_1:4,P00552,1.23462,NO,134,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-0.969,-4.314,3.345,,0.421,B,B,0.75,0.31,0.733,,49.62,HAB,-1.057,0.168804,0.00270812,1.23462 kka2_1:4_D5R,kka2_1:4_5,Kka2,kka2_1:4,P00552,1.23464,NO,5,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.306,-3.57,2.264,,,,,,,,,71.59,PAO,-1.784,0.168804,0.00222864,1.23464 kka2_1:4_A108L,kka2_1:4_108,Kka2,kka2_1:4,P00552,1.23486,NO,108,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.061,-2.851,0.79,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.168804,0.00751209,1.23486 kka2_1:8_G234K,kka2_1:8_234,Kka2,kka2_1:8,P00552,1.2349,NO,234,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-2.9,-2.482,-0.418,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.100394,0.00984449,1.2349 kka2_1:8_G234K,kka2_1:8_234,Kka2,kka2_1:8,P00552,1.2349,NO,234,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-2.9,-2.482,-0.418,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.100394,0.00984449,1.2349 kka2_1:8_S251E,kka2_1:8_251,Kka2,kka2_1:8,P00552,1.23494,NO,251,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.636,-2.355,-0.281,,0.712,H,A,0.27,-0.25,,,71.59,APP,-2.09367,0.100394,0.0138916,1.23494 kka2_1:8_S251E,kka2_1:8_251,Kka2,kka2_1:8,P00552,1.23494,NO,251,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.636,-2.355,-0.281,,0.712,H,A,0.27,-0.25,,,71.59,APP,-2.09367,0.100394,0.0138916,1.23494 WW_domain_Q195R,WW_domain_195,Yap65,WW_domain,P46937,1.23502,NO,195,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-1.839,-2.406,0.567,5.22735,,,,,,1.803,,70.04,APP,-1.719,0.153962,0.00394344,1.23502 kka2_1:8_A166K,kka2_1:8_166,Kka2,kka2_1:8,P00552,1.23504,NO,166,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.407,-3.569,1.162,,0.534,,B,1.04,1.03,13.995,13.995,71.59,HHO,-2.421,0.100394,0.00799912,1.23504 kka2_1:8_A166K,kka2_1:8_166,Kka2,kka2_1:8,P00552,1.23504,NO,166,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.407,-3.569,1.162,,0.534,,B,1.04,1.03,13.995,13.995,71.59,HHO,-2.421,0.100394,0.00799912,1.23504 kka2_1:4_T130C,kka2_1:4_130,Kka2,kka2_1:4,P00552,1.23512,NO,130,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.392,-3.62,1.228,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.168804,0.00804204,1.23512 kka2_1:4_G21R,kka2_1:4_21,Kka2,kka2_1:4,P00552,1.23523,NO,21,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.368,-3.948,2.58,,0.586,T,l,0.75,-0.75,3.075,,71.59,HOH,-2.10167,0.168804,0.00709648,1.23523 kka2_1:8_I221L,kka2_1:8_221,Kka2,kka2_1:8,P00552,1.23531,NO,221,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.739,-1.153,-0.586,,,H,A,1.52,-1.15,1.599,,71.59,AHH,-1.08367,0.100394,0.00945908,1.23531 kka2_1:8_I221L,kka2_1:8_221,Kka2,kka2_1:8,P00552,1.23531,NO,221,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.739,-1.153,-0.586,,,H,A,1.52,-1.15,1.599,,71.59,AHH,-1.08367,0.100394,0.00945908,1.23531 beta-lactamase_0_E108S,beta-lactamase_0_108,TEM-1,beta-lactamase_0,P62593,1.23535,NO,108,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.46,-2.354,0.894,,0.572,G,A,1.04,1.87,8.602,8.602,72.73,PAB,-1.437,0.0500837,0.00413372,1.23535 kka2_1:4_E231C,kka2_1:4_231,Kka2,kka2_1:4,P00552,1.2354,NO,231,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.002,-3.282,1.28,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.168804,0.00732383,1.2354 kka2_1:8_S114F,kka2_1:8_114,Kka2,kka2_1:8,P00552,1.23544,NO,114,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.527,-4.392,1.865,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.100394,0.00705262,1.23544 kka2_1:8_S114F,kka2_1:8_114,Kka2,kka2_1:8,P00552,1.23544,NO,114,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.527,-4.392,1.865,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.100394,0.00705262,1.23544 kka2_1:4_A14P,kka2_1:4_14,Kka2,kka2_1:4,P00552,1.23566,NO,14,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.837,-3.126,1.289,,0.728,G,A,0.46,0.7,0.36,,71.59,HHH,-1.82567,0.168804,0.00706614,1.23566 kka2_1:8_T73E,kka2_1:8_73,Kka2,kka2_1:8,P00552,1.23569,NO,73,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.51,-2.977,0.467,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.100394,0.00628605,1.23569 kka2_1:8_T73E,kka2_1:8_73,Kka2,kka2_1:8,P00552,1.23569,NO,73,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.51,-2.977,0.467,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.100394,0.00628605,1.23569 kka2_1:4_V75C,kka2_1:4_75,Kka2,kka2_1:4,P00552,1.23571,NO,75,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-2.06,-4.904,2.844,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.168804,0.00693733,1.23571 kka2_1:8_A25D,kka2_1:8_25,Kka2,kka2_1:8,P00552,1.23572,NO,25,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.496,-2.743,0.247,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.100394,0.00595636,1.23572 kka2_1:8_A25D,kka2_1:8_25,Kka2,kka2_1:8,P00552,1.23572,NO,25,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.496,-2.743,0.247,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.100394,0.00595636,1.23572 beta-lactamase_0_D212A,beta-lactamase_0_212,TEM-1,beta-lactamase_0,P62593,1.23579,NO,212,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.624,-2.64,1.016,,0.037,,b,0.75,-0.58,3.34,,74.48,HAB,-1.77667,0.0500837,0.00644302,1.23579 kka2_1:4_A150H,kka2_1:4_150,Kka2,kka2_1:4,P00552,1.23581,NO,150,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.949,-4.695,3.746,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.168804,0.0045009,1.23581 kka2_1:8_A79H,kka2_1:8_79,Kka2,kka2_1:8,P00552,1.23581,NO,79,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.368,-3.321,0.953,,0.563,.,B,0.46,-0.43,,,71.59,HHH,-1.752,0.100394,0.00664821,1.23581 kka2_1:8_A79H,kka2_1:8_79,Kka2,kka2_1:8,P00552,1.23581,NO,79,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.368,-3.321,0.953,,0.563,.,B,0.46,-0.43,,,71.59,HHH,-1.752,0.100394,0.00664821,1.23581 kka2_1:8_D5N,kka2_1:8_5,Kka2,kka2_1:8,P00552,1.23584,NO,5,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.306,-3.103,1.797,,,,,,,1.147,,71.59,PAO,-1.784,0.100394,0.00222864,1.23584 kka2_1:8_D5N,kka2_1:8_5,Kka2,kka2_1:8,P00552,1.23584,NO,5,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.306,-3.103,1.797,,,,,,,1.147,,71.59,PAO,-1.784,0.100394,0.00222864,1.23584 kka2_1:4_E230A,kka2_1:4_230,Kka2,kka2_1:4,P00552,1.23589,NO,230,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.672,-2.43,-0.242,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.168804,0.00920051,1.23589 beta-lactamase_0_C121N,beta-lactamase_0_121,TEM-1,beta-lactamase_0,P62593,1.2361,NO,121,C,N,CN,Special,Polar,5.07,5.47157,0.401575,139,121,132,11,108.5,114.1,5.6,-0.953,-4.045,3.092,,,H,A,0.46,-0.81,3.302,,63.29,HOP,-1.46767,0.0500837,0.000744322,1.2361 kka2_1:4_T72E,kka2_1:4_72,Kka2,kka2_1:4,P00552,1.23635,NO,72,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.38,-2.356,-0.024,,0.784,H,A,0.82,0.29,6.463,,65.53,HPP,-2.238,0.168804,0.00750756,1.23635 kka2_1:4_L243K,kka2_1:4_243,Kka2,kka2_1:4,P00552,1.23636,NO,243,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-2.651,-3.021,0.37,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.168804,0.00884927,1.23636 beta-lactamase_0_E119Q,beta-lactamase_0_119,TEM-1,beta-lactamase_0,P62593,1.2364,NO,119,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.412,-2.449,1.037,,0.358,H,A,1.04,0.51,3.396,,63.99,BAH,-1.623,0.0500837,0.00386966,1.2364 kka2_1:4_V80M,kka2_1:4_80,Kka2,kka2_1:4,P00552,1.23641,NO,80,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.144,-4.231,3.087,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.168804,0.00488211,1.23641 kka2_1:4_A9V,kka2_1:4_9,Kka2,kka2_1:4,P00552,1.2366,NO,9,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.079,-2.362,0.283,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.168804,0.00273264,1.2366 kka2_1:4_M178Q,kka2_1:4_178,Kka2,kka2_1:4,P00552,1.23667,NO,178,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-3.206,-2.478,-0.728,,0.554,.,b,0.55,0.68,9.913,9.913,71.59,BHO,-2.154,0.168804,0.00717253,1.23667 kka2_1:8_H139F,kka2_1:8_139,Kka2,kka2_1:8,P00552,1.23667,NO,139,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-2.809,-3.506,0.697,,0.471,H,A,0.17,0.68,28.583,28.583,63.64,BBB,-2.22,0.100394,0.00734779,1.23667 kka2_1:8_H139F,kka2_1:8_139,Kka2,kka2_1:8,P00552,1.23667,NO,139,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-2.809,-3.506,0.697,,0.471,H,A,0.17,0.68,28.583,28.583,63.64,BBB,-2.22,0.100394,0.00734779,1.23667 kka2_1:8_A79D,kka2_1:8_79,Kka2,kka2_1:8,P00552,1.23669,NO,79,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.368,-2.473,0.105,,0.563,.,B,0.46,-0.43,,,71.59,HHH,-1.752,0.100394,0.00664821,1.23669 kka2_1:8_A79D,kka2_1:8_79,Kka2,kka2_1:8,P00552,1.23669,NO,79,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.368,-2.473,0.105,,0.563,.,B,0.46,-0.43,,,71.59,HHH,-1.752,0.100394,0.00664821,1.23669 beta-lactamase_0_E87S,beta-lactamase_0_87,TEM-1,beta-lactamase_0,P62593,1.23677,NO,87,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.421,-3.382,1.961,,0.048,,B,1.04,0.92,1.159,,64.69,PAP,-1.969,0.0500837,0.00337888,1.23677 kka2_1:4_A108N,kka2_1:4_108,Kka2,kka2_1:4,P00552,1.23688,NO,108,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.061,-3.827,1.766,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.168804,0.00751209,1.23688 kka2_1:8_V75T,kka2_1:8_75,Kka2,kka2_1:8,P00552,1.23695,NO,75,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-2.06,-2.915,0.855,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.100394,0.00693733,1.23695 kka2_1:8_V75T,kka2_1:8_75,Kka2,kka2_1:8,P00552,1.23695,NO,75,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-2.06,-2.915,0.855,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.100394,0.00693733,1.23695 kka2_1:4_S68C,kka2_1:4_68,Kka2,kka2_1:4,P00552,1.23727,NO,68,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.623,-3.588,0.965,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.168804,0.00608265,1.23727 kka2_1:4_E149D,kka2_1:4_149,Kka2,kka2_1:4,P00552,1.23729,NO,149,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.994,-2.359,0.365,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.168804,0.00803343,1.23729 beta-lactamase_0_F58N,beta-lactamase_0_58,TEM-1,beta-lactamase_0,P62593,1.2374,NO,58,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-2.914,-3.795,0.881,,0.266,E,B,0.58,-0.07,24.637,24.637,77.62,PHB,-2.059,0.0500837,0.00523369,1.2374 kka2_1:4_L123I,kka2_1:4_123,Kka2,kka2_1:4,P00552,1.2375,NO,123,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.888,-2.453,1.565,,0.007,H,A,0.55,-0.4,1.447,,48.86,BHB,-1.301,0.168804,0.00325188,1.2375 beta-lactamase_0_H94Y,beta-lactamase_0_94,TEM-1,beta-lactamase_0,P62593,1.23754,NO,94,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-2.5,-4.209,1.709,,0.776,,B,0.17,1.24,1.176,,77.62,HBH,-1.872,0.0500837,0.00389226,1.23754 kka2_1:2_A56P,kka2_1:2_56,Kka2,kka2_1:2,P00552,1.23754,NO,56,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.083,-1.768,-0.315,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.295029,0.00717715,1.23754 beta-lactamase_0_S233M,beta-lactamase_0_233,TEM-1,beta-lactamase_0,P62593,1.23761,NO,233,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.886,-4.626,2.74,,0.016,E,B,0.27,-1.01,3.579,,77.62,BPO,-1.17267,0.0500837,0.00311415,1.23761 kka2_1:8_Q4T,kka2_1:8_4,Kka2,kka2_1:8,P00552,1.23765,NO,4,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.361,-3.156,0.795,,,,,,,2.026,,71.59,APA,-1.95533,0.100394,0.00239179,1.23765 kka2_1:8_Q4T,kka2_1:8_4,Kka2,kka2_1:8,P00552,1.23765,NO,4,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.361,-3.156,0.795,,,,,,,2.026,,71.59,APA,-1.95533,0.100394,0.00239179,1.23765 kka2_1:4_E160N,kka2_1:4_160,Kka2,kka2_1:4,P00552,1.23769,NO,160,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.683,-2.876,1.193,,0.989,G,A,1.04,2.28,2.531,,71.59,AAA,-1.36133,0.168804,0.00935762,1.23769 kka2_1:8_A255M,kka2_1:8_255,Kka2,kka2_1:8,P00552,1.23769,NO,255,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.715,-4.815,3.1,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.100394,0.0126809,1.23769 kka2_1:8_A255M,kka2_1:8_255,Kka2,kka2_1:8,P00552,1.23769,NO,255,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.715,-4.815,3.1,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.100394,0.0126809,1.23769 kka2_1:8_A35Q,kka2_1:8_35,Kka2,kka2_1:8,P00552,1.2379,NO,35,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.127,-3.255,1.128,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.100394,0.00630016,1.2379 kka2_1:8_A35Q,kka2_1:8_35,Kka2,kka2_1:8,P00552,1.2379,NO,35,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.127,-3.255,1.128,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.100394,0.00630016,1.2379 kka2_1:8_I2Q,kka2_1:8_2,Kka2,kka2_1:8,P00552,1.23809,NO,2,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.787,-3.979,2.192,,,,,,,,,71.59,HHA,-1.92433,0.100394,0.00246644,1.23809 kka2_1:8_I2Q,kka2_1:8_2,Kka2,kka2_1:8,P00552,1.23809,NO,2,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.787,-3.979,2.192,,,,,,,,,71.59,HHA,-1.92433,0.100394,0.00246644,1.23809 kka2_1:4_E231F,kka2_1:4_231,Kka2,kka2_1:4,P00552,1.23812,NO,231,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.002,-4.394,2.392,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.168804,0.00732383,1.23812 kka2_1:8_G6D,kka2_1:8_6,Kka2,kka2_1:8,P00552,1.23817,NO,6,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.685,-3.441,1.756,,,,,,,,,71.59,AOH,-1.639,0.100394,0.00204693,1.23817 kka2_1:8_G6D,kka2_1:8_6,Kka2,kka2_1:8,P00552,1.23817,NO,6,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.685,-3.441,1.756,,,,,,,,,71.59,AOH,-1.639,0.100394,0.00204693,1.23817 beta-lactamase_0_R275Q,beta-lactamase_0_275,TEM-1,beta-lactamase_0,P62593,1.23818,NO,275,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.397,,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.0500837,0.0141984,1.23818 kka2_1:2_S40E,kka2_1:2_40,Kka2,kka2_1:2,P00552,1.23847,NO,40,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.645,-2.141,-0.504,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.295029,0.00693477,1.23847 kka2_1:8_F20Y,kka2_1:8_20,Kka2,kka2_1:8,P00552,1.23866,NO,20,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-3.354,-4.354,1,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.100394,0.00701744,1.23866 kka2_1:8_F20Y,kka2_1:8_20,Kka2,kka2_1:8,P00552,1.23866,NO,20,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-3.354,-4.354,1,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.100394,0.00701744,1.23866 kka2_1:4_L193F,kka2_1:4_193,Kka2,kka2_1:4,P00552,1.23868,NO,193,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.983,-3.816,2.833,,,G,A,1.59,-1.03,6.577,,65.53,OHO,-0.965333,0.168804,0.00480179,1.23868 kka2_1:2_S40C,kka2_1:2_40,Kka2,kka2_1:2,P00552,1.23886,NO,40,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.645,-3.648,1.003,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.295029,0.00693477,1.23886 kka2_1:4_H8L,kka2_1:4_8,Kka2,kka2_1:4,P00552,1.2389,NO,8,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-2.759,-3.165,0.406,,,,,,,,,71.59,HBH,-2.25467,0.168804,0.00256422,1.2389 beta-lactamase_0_H110E,beta-lactamase_0_110,TEM-1,beta-lactamase_0,P62593,1.23892,NO,110,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-1.706,-2.766,1.06,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.0500837,0.00441499,1.23892 kka2_1:2_E149V,kka2_1:2_149,Kka2,kka2_1:2,P00552,1.23901,NO,149,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.994,-3.648,1.654,,0.674,H,A,1.04,1.63,15.361,15.361,71.59,HAH,-1.59667,0.295029,0.00803343,1.23901 kka2_1:4_N200D,kka2_1:4_200,Kka2,kka2_1:4,P00552,1.23906,NO,200,N,D,ND,Polar,negativeCharge,5.47157,5.0516,-0.419975,23,132,133,1,114.1,111.1,-3,-2.446,-2.235,-0.211,,0.756,T,L,0.61,-0.08,1.746,,64.39,APO,-2.08,0.168804,0.00838549,1.23906 kka2_1:8_S251Y,kka2_1:8_251,Kka2,kka2_1:8,P00552,1.23906,NO,251,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.636,-4.395,1.759,,0.712,H,A,0.27,-0.25,,,71.59,APP,-2.09367,0.100394,0.0138916,1.23906 kka2_1:8_S251Y,kka2_1:8_251,Kka2,kka2_1:8,P00552,1.23906,NO,251,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.636,-4.395,1.759,,0.712,H,A,0.27,-0.25,,,71.59,APP,-2.09367,0.100394,0.0138916,1.23906 kka2_1:8_S40Q,kka2_1:8_40,Kka2,kka2_1:8,P00552,1.23906,NO,40,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.645,-2.827,0.182,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.100394,0.00693477,1.23906 kka2_1:8_S40Q,kka2_1:8_40,Kka2,kka2_1:8,P00552,1.23906,NO,40,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.645,-2.827,0.182,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.100394,0.00693477,1.23906 kka2_1:2_A65M,kka2_1:2_65,Kka2,kka2_1:2,P00552,1.23907,NO,65,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.744,-3.547,1.803,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.295029,0.00709258,1.23907 kka2_1:8_Q163Y,kka2_1:8_163,Kka2,kka2_1:8,P00552,1.23911,NO,163,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.162,-4.27,2.108,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.100394,0.00719507,1.23911 kka2_1:8_Q163Y,kka2_1:8_163,Kka2,kka2_1:8,P00552,1.23911,NO,163,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.162,-4.27,2.108,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.100394,0.00719507,1.23911 kka2_1:2_P249E,kka2_1:2_249,Kka2,kka2_1:2,P00552,1.23913,NO,249,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.867,-3.804,1.937,,0.406,.,B,0.52,-0.01,0.76,,92.05,HOA,-1.66867,0.295029,0.011045,1.23913 kka2_1:2_G181H,kka2_1:2_181,Kka2,kka2_1:2,P00552,1.23915,NO,181,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-2.698,-2.933,0.235,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.295029,0.00728319,1.23915 kka2_1:8_I2E,kka2_1:8_2,Kka2,kka2_1:8,P00552,1.23939,NO,2,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.787,-3.519,1.732,,,,,,,,,71.59,HHA,-1.92433,0.100394,0.00246644,1.23939 kka2_1:8_I2E,kka2_1:8_2,Kka2,kka2_1:8,P00552,1.23939,NO,2,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.787,-3.519,1.732,,,,,,,,,71.59,HHA,-1.92433,0.100394,0.00246644,1.23939 kka2_1:2_V242I,kka2_1:2_242,Kka2,kka2_1:2,P00552,1.23941,NO,242,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-2.687,-3.231,0.544,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.295029,0.0102575,1.23941 kka2_1:4_A166Q,kka2_1:4_166,Kka2,kka2_1:4,P00552,1.23942,NO,166,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.407,-3.207,0.8,,0.534,.,B,0.46,1.03,,,71.59,HHO,-2.421,0.168804,0.00799912,1.23942 kka2_1:8_T130I,kka2_1:8_130,Kka2,kka2_1:8,P00552,1.23944,NO,130,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.392,-3.995,1.603,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.100394,0.00804204,1.23944 kka2_1:8_T130I,kka2_1:8_130,Kka2,kka2_1:8,P00552,1.23944,NO,130,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.392,-3.995,1.603,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.100394,0.00804204,1.23944 kka2_1:8_T225L,kka2_1:8_225,Kka2,kka2_1:8,P00552,1.23944,NO,225,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.393,-2.612,0.219,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.100394,0.0113598,1.23944 kka2_1:8_T225L,kka2_1:8_225,Kka2,kka2_1:8,P00552,1.23944,NO,225,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.393,-2.612,0.219,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.100394,0.0113598,1.23944 beta-lactamase_0_E87M,beta-lactamase_0_87,TEM-1,beta-lactamase_0,P62593,1.23946,NO,87,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.421,-4.574,3.153,,0.048,,B,1.04,0.92,1.159,,64.69,PAP,-1.969,0.0500837,0.00337888,1.23946 kka2_1:4_Q100A,kka2_1:4_100,Kka2,kka2_1:4,P00552,1.23952,NO,100,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.77,-2.603,-0.167,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.168804,0.0066405,1.23952 kka2_1:2_T125K,kka2_1:2_125,Kka2,kka2_1:2,P00552,1.23963,NO,125,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.622,-2.941,0.319,,0.791,T,A,0.22,0.33,2.029,,92.05,BPH,-1.56933,0.295029,0.00821755,1.23963 kka2_1:8_A247P,kka2_1:8_247,Kka2,kka2_1:8,P00552,1.23972,NO,247,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.459,-2.362,-0.097,,1.01,S,A,0.46,0.65,18.904,18.904,92.05,HHH,-2.197,0.100394,0.0102428,1.23972 kka2_1:8_A247P,kka2_1:8_247,Kka2,kka2_1:8,P00552,1.23972,NO,247,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.459,-2.362,-0.097,,1.01,S,A,0.46,0.65,18.904,18.904,92.05,HHH,-2.197,0.100394,0.0102428,1.23972 beta-lactamase_0_E210R,beta-lactamase_0_210,TEM-1,beta-lactamase_0,P62593,1.23978,NO,210,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.319,-3.045,0.726,,0.476,H,A,1.04,0.75,3.618,,77.62,HAH,-1.88567,0.0500837,0.00663582,1.23978 beta-lactamase_0_E166I,beta-lactamase_0_166,TEM-1,beta-lactamase_0,P62593,1.23988,NO,166,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.756,-3.874,2.118,,0.508,G,A,1.04,1.05,17.227,17.227,73.08,OAH,-1.42233,0.0500837,0.00512989,1.23988 beta-lactamase_0_K30H,beta-lactamase_0_30,TEM-1,beta-lactamase_0,P62593,1.23989,NO,30,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-2.307,-4.558,2.251,,0.142,H,A,2.34,-0.65,1.491,,93.01,HBH,-2.32833,0.0500837,0.00448593,1.23989 kka2_1:2_L7A,kka2_1:2_7,Kka2,kka2_1:2,P00552,1.24012,NO,7,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.926,-3.033,1.107,,,,,,,3.012,,71.59,OHB,-2.12333,0.295029,0.00269456,1.24012 kka2_1:8_A191L,kka2_1:8_191,Kka2,kka2_1:8,P00552,1.24018,NO,191,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.831,-3.249,2.418,,,,b,1.04,-0.94,1.306,,50,AHO,-0.868667,0.100394,0.00338807,1.24018 kka2_1:8_A191L,kka2_1:8_191,Kka2,kka2_1:8,P00552,1.24018,NO,191,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.831,-3.249,2.418,,,,b,1.04,-0.94,1.306,,50,AHO,-0.868667,0.100394,0.00338807,1.24018 kka2_1:8_V46S,kka2_1:8_46,Kka2,kka2_1:8,P00552,1.24027,NO,46,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-2.62,-2.564,-0.056,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.100394,0.00631301,1.24027 kka2_1:8_V46S,kka2_1:8_46,Kka2,kka2_1:8,P00552,1.24027,NO,46,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-2.62,-2.564,-0.056,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.100394,0.00631301,1.24027 kka2_1:8_G181Y,kka2_1:8_181,Kka2,kka2_1:8,P00552,1.24028,NO,181,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-2.698,-3.473,0.775,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.100394,0.00728319,1.24028 kka2_1:8_G181Y,kka2_1:8_181,Kka2,kka2_1:8,P00552,1.24028,NO,181,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-2.698,-3.473,0.775,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.100394,0.00728319,1.24028 kka2_1:4_G151Y,kka2_1:4_151,Kka2,kka2_1:4,P00552,1.24033,NO,151,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.873,-4.442,3.569,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.168804,0.00339918,1.24033 kka2_1:4_R173I,kka2_1:4_173,Kka2,kka2_1:4,P00552,1.24033,NO,173,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.407,-4.054,1.647,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.168804,0.00784999,1.24033 kka2_1:8_G10N,kka2_1:8_10,Kka2,kka2_1:8,P00552,1.24042,NO,10,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.921,-2.575,0.654,,,,,,,1.862,,71.59,HOP,-2.10733,0.100394,0.00289233,1.24042 kka2_1:8_G10N,kka2_1:8_10,Kka2,kka2_1:8,P00552,1.24042,NO,10,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.921,-2.575,0.654,,,,,,,1.862,,71.59,HOP,-2.10733,0.100394,0.00289233,1.24042 kka2_1:4_E199T,kka2_1:4_199,Kka2,kka2_1:4,P00552,1.24043,NO,199,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.234,-2.695,0.461,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.168804,0.00854122,1.24043 kka2_1:8_A65K,kka2_1:8_65,Kka2,kka2_1:8,P00552,1.24062,NO,65,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.744,-3.037,1.293,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.100394,0.00709258,1.24062 kka2_1:8_A65K,kka2_1:8_65,Kka2,kka2_1:8,P00552,1.24062,NO,65,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.744,-3.037,1.293,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.100394,0.00709258,1.24062 kka2_1:4_R143Q,kka2_1:4_143,Kka2,kka2_1:4,P00552,1.24095,NO,143,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.525,-3.295,0.77,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.168804,0.00662247,1.24095 kka2_1:4_D180N,kka2_1:4_180,Kka2,kka2_1:4,P00552,1.24098,NO,180,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.416,-3.09,0.674,,1.03,S,a,0.29,1.5,14.668,14.668,71.59,OAO,-2.02933,0.168804,0.00756412,1.24098 kka2_1:2_L165E,kka2_1:2_165,Kka2,kka2_1:2,P00552,1.2411,NO,165,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-2.453,-2.802,0.349,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.295029,0.00801161,1.2411 beta-lactamase_0_G216Q,beta-lactamase_0_216,TEM-1,beta-lactamase_0,P62593,1.24112,NO,216,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.477,-3.862,2.385,,0.437,I,A,0.29,-0.58,0.834,,74.48,HOO,-1.68067,0.0500837,0.00639568,1.24112 kka2_1:8_G164H,kka2_1:8_164,Kka2,kka2_1:8,P00552,1.24116,NO,164,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.869,-4.642,3.773,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.100394,0.00442091,1.24116 kka2_1:8_G164H,kka2_1:8_164,Kka2,kka2_1:8,P00552,1.24116,NO,164,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.869,-4.642,3.773,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.100394,0.00442091,1.24116 beta-lactamase_0_V214N,beta-lactamase_0_214,TEM-1,beta-lactamase_0,P62593,1.24122,NO,214,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.299,-3.962,2.663,,0.375,S,A,0.44,-0.44,3.712,,74.48,BHH,-1.53733,0.0500837,0.00628442,1.24122 kka2_1:8_A176D,kka2_1:8_176,Kka2,kka2_1:8,P00552,1.24139,NO,176,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.621,-2.955,1.334,,0.806,H,A,0.46,-0.03,18.904,18.904,65.53,BHB,-2.26667,0.100394,0.0083587,1.24139 kka2_1:8_A176D,kka2_1:8_176,Kka2,kka2_1:8,P00552,1.24139,NO,176,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.621,-2.955,1.334,,0.806,H,A,0.46,-0.03,18.904,18.904,65.53,BHB,-2.26667,0.100394,0.0083587,1.24139 kka2_1:8_P249E,kka2_1:8_249,Kka2,kka2_1:8,P00552,1.24144,NO,249,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.867,-3.804,1.937,,0.406,.,B,0.52,-0.01,1.699,,92.05,HOA,-1.66867,0.100394,0.011045,1.24144 kka2_1:8_P249E,kka2_1:8_249,Kka2,kka2_1:8,P00552,1.24144,NO,249,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.867,-3.804,1.937,,0.406,.,B,0.52,-0.01,1.699,,92.05,HOA,-1.66867,0.100394,0.011045,1.24144 kka2_1:4_R143N,kka2_1:4_143,Kka2,kka2_1:4,P00552,1.24146,NO,143,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.525,-3.927,1.402,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.168804,0.00662247,1.24146 kka2_1:4_Q4K,kka2_1:4_4,Kka2,kka2_1:4,P00552,1.24147,NO,4,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.361,-3.145,0.784,,,,,,,2.026,,71.59,APA,-1.95533,0.168804,0.00239179,1.24147 kka2_1:8_R143V,kka2_1:8_143,Kka2,kka2_1:8,P00552,1.24158,NO,143,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.525,-2.516,-0.009,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.100394,0.00662247,1.24158 kka2_1:8_R143V,kka2_1:8_143,Kka2,kka2_1:8,P00552,1.24158,NO,143,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.525,-2.516,-0.009,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.100394,0.00662247,1.24158 kka2_1:8_T146I,kka2_1:8_146,Kka2,kka2_1:8,P00552,1.24161,NO,146,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.978,-3.15,0.172,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.100394,0.00606474,1.24161 kka2_1:8_T146I,kka2_1:8_146,Kka2,kka2_1:8,P00552,1.24161,NO,146,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.978,-3.15,0.172,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.100394,0.00606474,1.24161 kka2_1:4_G10S,kka2_1:4_10,Kka2,kka2_1:4,P00552,1.24168,NO,10,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.921,-3.23,1.309,,,,,,,1.862,,71.59,HOP,-2.10733,0.168804,0.00289233,1.24168 kka2_1:8_R173T,kka2_1:8_173,Kka2,kka2_1:8,P00552,1.24177,NO,173,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.407,-3.026,0.619,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.100394,0.00784999,1.24177 kka2_1:8_R173T,kka2_1:8_173,Kka2,kka2_1:8,P00552,1.24177,NO,173,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.407,-3.026,0.619,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.100394,0.00784999,1.24177 kka2_1:8_I254Q,kka2_1:8_254,Kka2,kka2_1:8,P00552,1.2419,NO,254,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.933,-4.193,2.26,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.100394,0.0132375,1.2419 kka2_1:8_I254Q,kka2_1:8_254,Kka2,kka2_1:8,P00552,1.2419,NO,254,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.933,-4.193,2.26,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.100394,0.0132375,1.2419 kka2_1:2_A166K,kka2_1:2_166,Kka2,kka2_1:2,P00552,1.24192,NO,166,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.407,-3.569,1.162,,0.534,.,B,0.46,1.03,23.175,23.175,71.59,HHO,-2.421,0.295029,0.00799912,1.24192 kka2_1:2_R44K,kka2_1:2_44,Kka2,kka2_1:2,P00552,1.24212,NO,44,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.062,-2.763,0.701,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.295029,0.00745043,1.24212 kka2_1:2_A56H,kka2_1:2_56,Kka2,kka2_1:2,P00552,1.24214,NO,56,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.083,-4.875,2.792,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.295029,0.00717715,1.24214 kka2_1:8_E111L,kka2_1:8_111,Kka2,kka2_1:8,P00552,1.24226,NO,111,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.28,-3.101,0.821,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.100394,0.00746789,1.24226 kka2_1:8_E111L,kka2_1:8_111,Kka2,kka2_1:8,P00552,1.24226,NO,111,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.28,-3.101,0.821,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.100394,0.00746789,1.24226 kka2_1:8_T225W,kka2_1:8_225,Kka2,kka2_1:8,P00552,1.24226,NO,225,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.393,-5.412,3.019,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.100394,0.0113598,1.24226 kka2_1:8_T225W,kka2_1:8_225,Kka2,kka2_1:8,P00552,1.24226,NO,225,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.393,-5.412,3.019,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.100394,0.0113598,1.24226 kka2_1:2_T225H,kka2_1:2_225,Kka2,kka2_1:2,P00552,1.24243,NO,225,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.393,-3.458,1.065,,0.036,H,A,0.22,-1.22,4.554,,63.64,HPB,-1.58733,0.295029,0.0113598,1.24243 kka2_1:4_A166W,kka2_1:4_166,Kka2,kka2_1:4,P00552,1.24246,NO,166,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.407,-5.55,3.143,,0.534,.,B,0.46,1.03,,,71.59,HHO,-2.421,0.168804,0.00799912,1.24246 kka2_1:2_A25E,kka2_1:2_25,Kka2,kka2_1:2,P00552,1.24254,NO,25,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.496,-1.817,-0.679,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.295029,0.00595636,1.24254 kka2_1:8_R177W,kka2_1:8_177,Kka2,kka2_1:8,P00552,1.24256,NO,177,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.282,-5.514,3.232,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.100394,0.00768224,1.24256 kka2_1:8_R177W,kka2_1:8_177,Kka2,kka2_1:8,P00552,1.24256,NO,177,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.282,-5.514,3.232,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.100394,0.00768224,1.24256 kka2_1:2_G234A,kka2_1:2_234,Kka2,kka2_1:2,P00552,1.24257,NO,234,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-2.9,-2.255,-0.645,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.295029,0.00984449,1.24257 kka2_1:4_A71N,kka2_1:4_71,Kka2,kka2_1:4,P00552,1.24262,NO,71,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.824,-2.731,0.907,,0.553,H,A,0.46,0.08,5.76,,64.39,HHP,-1.74033,0.168804,0.00727707,1.24262 kka2_1:2_Q252A,kka2_1:2_252,Kka2,kka2_1:2,P00552,1.24281,NO,252,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.63,-2.051,-0.579,,0.906,H,A,0.64,0.35,5.613,,92.05,PPB,-2.20733,0.295029,0.0121001,1.24281 kka2_1:8_V75C,kka2_1:8_75,Kka2,kka2_1:8,P00552,1.24287,NO,75,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-2.06,-4.904,2.844,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.100394,0.00693733,1.24287 kka2_1:8_V75C,kka2_1:8_75,Kka2,kka2_1:8,P00552,1.24287,NO,75,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-2.06,-4.904,2.844,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.100394,0.00693733,1.24287 kka2_1:4_V83C,kka2_1:4_83,Kka2,kka2_1:4,P00552,1.24289,NO,83,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-2.567,-5.124,2.557,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.168804,0.00650486,1.24289 kka2_1:4_D180T,kka2_1:4_180,Kka2,kka2_1:4,P00552,1.24293,NO,180,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.416,-3.001,0.585,,1.03,S,a,0.29,1.5,14.668,14.668,71.59,OAO,-2.02933,0.168804,0.00756412,1.24293 beta-lactamase_0_L100E,beta-lactamase_0_100,TEM-1,beta-lactamase_0,P62593,1.24295,NO,100,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.218,-3.935,2.717,,0.343,,B,0.55,0.13,1.373,,63.29,AHH,-1.23467,0.0500837,0.00413885,1.24295 kka2_1:4_L243C,kka2_1:4_243,Kka2,kka2_1:4,P00552,1.24296,NO,243,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-2.651,-2.68,0.029,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.168804,0.00884927,1.24296 kka2_1:2_S114E,kka2_1:2_114,Kka2,kka2_1:2,P00552,1.24297,NO,114,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.527,-2.055,-0.472,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.295029,0.00705262,1.24297 kka2_1:8_H8K,kka2_1:8_8,Kka2,kka2_1:8,P00552,1.24303,NO,8,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-2.759,-3.463,0.704,,,,,,,,,71.59,HBH,-2.25467,0.100394,0.00256422,1.24303 kka2_1:8_H8K,kka2_1:8_8,Kka2,kka2_1:8,P00552,1.24303,NO,8,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-2.759,-3.463,0.704,,,,,,,,,71.59,HBH,-2.25467,0.100394,0.00256422,1.24303 kka2_1:4_R177N,kka2_1:4_177,Kka2,kka2_1:4,P00552,1.24306,NO,177,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.282,-2.629,0.347,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.168804,0.00768224,1.24306 kka2_1:8_R140A,kka2_1:8_140,Kka2,kka2_1:8,P00552,1.24312,NO,140,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.351,-2.609,1.258,,0.12,H,A,0.16,0.2,2.874,,53.03,BBH,-1.885,0.100394,0.00430167,1.24312 kka2_1:8_R140A,kka2_1:8_140,Kka2,kka2_1:8,P00552,1.24312,NO,140,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.351,-2.609,1.258,,0.12,H,A,0.16,0.2,2.874,,53.03,BBH,-1.885,0.100394,0.00430167,1.24312 kka2_1:4_E17R,kka2_1:4_17,Kka2,kka2_1:4,P00552,1.24313,NO,17,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.154,-2.815,0.661,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.168804,0.00688738,1.24313 kka2_1:8_D118Q,kka2_1:8_118,Kka2,kka2_1:8,P00552,1.24314,NO,118,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.07,-2.739,0.669,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.100394,0.0067852,1.24314 kka2_1:8_D118Q,kka2_1:8_118,Kka2,kka2_1:8,P00552,1.24314,NO,118,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.07,-2.739,0.669,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.100394,0.0067852,1.24314 kka2_1:2_H8Y,kka2_1:2_8,Kka2,kka2_1:2,P00552,1.24323,NO,8,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-2.759,-3.943,1.184,,,,,,,,,71.59,HBH,-2.25467,0.295029,0.00256422,1.24323 kka2_1:4_G74Q,kka2_1:4_74,Kka2,kka2_1:4,P00552,1.24344,NO,74,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.18,-3.052,1.872,,0.621,T,l,0.75,0.2,1.032,,64.39,POH,-1.91667,0.168804,0.00587035,1.24344 kka2_1:8_S40Y,kka2_1:8_40,Kka2,kka2_1:8,P00552,1.24344,NO,40,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.645,-4.369,1.724,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.100394,0.00693477,1.24344 kka2_1:8_S40Y,kka2_1:8_40,Kka2,kka2_1:8,P00552,1.24344,NO,40,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.645,-4.369,1.724,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.100394,0.00693477,1.24344 kka2_1:2_V16E,kka2_1:2_16,Kka2,kka2_1:2,P00552,1.24347,NO,16,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-3.087,-2.983,-0.104,,0.742,T,A,0.44,0.34,1.746,,71.59,HHA,-2.211,0.295029,0.00694011,1.24347 kka2_1:4_I2C,kka2_1:4_2,Kka2,kka2_1:4,P00552,1.24348,NO,2,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.787,-4.477,2.69,,,,,,,,,71.59,HHA,-1.92433,0.168804,0.00246644,1.24348 kka2_1:4_A25R,kka2_1:4_25,Kka2,kka2_1:4,P00552,1.24354,NO,25,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.496,-2.407,-0.089,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.168804,0.00595636,1.24354 kka2_1:2_G181N,kka2_1:2_181,Kka2,kka2_1:2,P00552,1.24365,NO,181,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-2.698,-3.022,0.324,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.295029,0.00728319,1.24365 kka2_1:4_A172K,kka2_1:4_172,Kka2,kka2_1:4,P00552,1.24366,NO,172,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.757,-3.042,1.285,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.168804,0.0079265,1.24366 kka2_1:4_E3N,kka2_1:4_3,Kka2,kka2_1:4,P00552,1.24366,NO,3,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.199,-3.328,1.129,,,,,,,7.22,,92.05,HAP,-2.11567,0.168804,0.00267607,1.24366 kka2_1:8_V242T,kka2_1:8_242,Kka2,kka2_1:8,P00552,1.24383,NO,242,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-2.687,-2.522,-0.165,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.100394,0.0102575,1.24383 kka2_1:8_V242T,kka2_1:8_242,Kka2,kka2_1:8,P00552,1.24383,NO,242,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-2.687,-2.522,-0.165,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.100394,0.0102575,1.24383 kka2_1:8_S251K,kka2_1:8_251,Kka2,kka2_1:8,P00552,1.2439,NO,251,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.636,-3.007,0.371,,0.712,H,A,0.27,-0.25,,,71.59,APP,-2.09367,0.100394,0.0138916,1.2439 kka2_1:8_S251K,kka2_1:8_251,Kka2,kka2_1:8,P00552,1.2439,NO,251,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.636,-3.007,0.371,,0.712,H,A,0.27,-0.25,,,71.59,APP,-2.09367,0.100394,0.0138916,1.2439 kka2_1:4_F20L,kka2_1:4_20,Kka2,kka2_1:4,P00552,1.24393,NO,20,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-3.354,-3.523,0.169,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.168804,0.00701744,1.24393 beta-lactamase_0_A222H,beta-lactamase_0_222,TEM-1,beta-lactamase_0,P62593,1.24401,NO,222,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.103,-2.705,0.602,,0.233,H,A,0.46,-0.25,2.015,,77.62,PHH,-1.63733,0.0500837,0.00466094,1.24401 kka2_1:2_A137V,kka2_1:2_137,Kka2,kka2_1:2,P00552,1.24416,NO,137,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.156,-2.289,0.133,,0.029,H,A,0.46,0.34,1.323,,63.26,PHB,-2.559,0.295029,0.00515054,1.24416 kka2_1:4_D134Q,kka2_1:4_134,Kka2,kka2_1:4,P00552,1.24421,NO,134,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.969,-3.77,2.801,,0.421,B,B,0.75,0.31,0.733,,49.62,HAB,-1.057,0.168804,0.00270812,1.24421 kka2_1:4_A166F,kka2_1:4_166,Kka2,kka2_1:4,P00552,1.24423,NO,166,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.407,-4.424,2.017,,0.534,.,B,0.46,1.03,,,71.59,HHO,-2.421,0.168804,0.00799912,1.24423 beta-lactamase_0_I280M,beta-lactamase_0_280,TEM-1,beta-lactamase_0,P62593,1.24427,NO,280,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.0500837,0.0530888,1.24427 kka2_1:2_S40V,kka2_1:2_40,Kka2,kka2_1:2,P00552,1.24432,NO,40,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.645,-3.735,1.09,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.295029,0.00693477,1.24432 kka2_1:8_A168M,kka2_1:8_168,Kka2,kka2_1:8,P00552,1.24436,NO,168,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.989,-4.833,2.844,,0.67,H,A,0.46,0.15,11.329,11.329,64.39,OHA,-2.12933,0.100394,0.00806773,1.24436 kka2_1:8_A168M,kka2_1:8_168,Kka2,kka2_1:8,P00552,1.24436,NO,168,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.989,-4.833,2.844,,0.67,H,A,0.46,0.15,11.329,11.329,64.39,OHA,-2.12933,0.100394,0.00806773,1.24436 kka2_1:8_D5K,kka2_1:8_5,Kka2,kka2_1:8,P00552,1.2444,NO,5,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.306,-3.094,1.788,,,,,,,1.147,,71.59,PAO,-1.784,0.100394,0.00222864,1.2444 kka2_1:8_D5K,kka2_1:8_5,Kka2,kka2_1:8,P00552,1.2444,NO,5,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.306,-3.094,1.788,,,,,,,1.147,,71.59,PAO,-1.784,0.100394,0.00222864,1.2444 beta-lactamase_0_T116E,beta-lactamase_0_116,TEM-1,beta-lactamase_0,P62593,1.24443,NO,116,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.28,-3.469,2.189,,0.115,E,B,0.22,-0.12,1.356,,67.48,HPH,-1.39967,0.0500837,0.00336175,1.24443 kka2_1:2_P45E,kka2_1:2_45,Kka2,kka2_1:2,P00552,1.24449,NO,45,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.774,-2.616,0.842,,0.669,,B,0.52,-0.76,4.882,,71.59,BOH,-2.152,0.295029,0.00590481,1.24449 beta-lactamase_0_I206V,beta-lactamase_0_206,TEM-1,beta-lactamase_0,P62593,1.24454,NO,206,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-2.429,-2.433,0.004,,0.173,H,A,0.48,-0.34,3.411,,77.62,HHA,-1.805,0.0500837,0.00528934,1.24454 kka2_1:2_E17H,kka2_1:2_17,Kka2,kka2_1:2,P00552,1.24457,NO,17,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.154,-3.247,1.093,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.295029,0.00688738,1.24457 kka2_1:2_R122W,kka2_1:2_122,Kka2,kka2_1:2,P00552,1.24458,NO,122,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.175,-5.581,3.406,,0.487,H,A,1.2,0.26,16.436,16.436,71.59,BBH,-1.53833,0.295029,0.00736512,1.24458 kka2_1:2_D23A,kka2_1:2_23,Kka2,kka2_1:2,P00552,1.24459,NO,23,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.459,-2.468,0.009,,0.695,E,B,0.75,-0.65,18.207,18.207,65.53,HAH,-1.94033,0.295029,0.007195,1.24459 beta-lactamase_0_A84N,beta-lactamase_0_84,TEM-1,beta-lactamase_0,P62593,1.24478,NO,84,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.651,-2.768,1.117,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.0500837,0.00503822,1.24478 kka2_1:8_A166T,kka2_1:8_166,Kka2,kka2_1:8,P00552,1.24479,NO,166,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.407,-1.912,-0.495,,0.534,,B,1.04,1.03,13.995,13.995,71.59,HHO,-2.421,0.100394,0.00799912,1.24479 kka2_1:8_A166T,kka2_1:8_166,Kka2,kka2_1:8,P00552,1.24479,NO,166,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.407,-1.912,-0.495,,0.534,,B,1.04,1.03,13.995,13.995,71.59,HHO,-2.421,0.100394,0.00799912,1.24479 kka2_1:8_A172H,kka2_1:8_172,Kka2,kka2_1:8,P00552,1.24495,NO,172,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.757,-4.807,3.05,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.100394,0.0079265,1.24495 kka2_1:8_A172H,kka2_1:8_172,Kka2,kka2_1:8,P00552,1.24495,NO,172,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.757,-4.807,3.05,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.100394,0.0079265,1.24495 kka2_1:2_D238V,kka2_1:2_238,Kka2,kka2_1:2,P00552,1.24505,NO,238,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.83,-3.676,0.846,,0.604,H,A,0.75,-0.33,22.789,22.789,92.05,HAB,-2.633,0.295029,0.0113863,1.24505 beta-lactamase_0_D271E,beta-lactamase_0_271,TEM-1,beta-lactamase_0,P62593,1.24508,NO,271,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.0500837,0.00752082,1.24508 kka2_1:8_D238A,kka2_1:8_238,Kka2,kka2_1:8,P00552,1.24525,NO,238,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.83,-1.842,-0.988,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.100394,0.0113863,1.24525 kka2_1:8_D238A,kka2_1:8_238,Kka2,kka2_1:8,P00552,1.24525,NO,238,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.83,-1.842,-0.988,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.100394,0.0113863,1.24525 kka2_1:4_Q155E,kka2_1:4_155,Kka2,kka2_1:4,P00552,1.2453,NO,155,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.606,-1.223,-1.383,,0.525,T,A,0.64,1.49,1.592,,63.64,APA,-1.726,0.168804,0.00641853,1.2453 beta-lactamase_0_L196C,beta-lactamase_0_196,TEM-1,beta-lactamase_0,P62593,1.24533,NO,196,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-2.478,-4.975,2.497,,0.518,S,A,0.55,1.35,6.513,6.513,77.62,AHH,-1.839,0.0500837,0.00512144,1.24533 Pab1_Q194C,Pab1_194,Pab1,Pab1,P04147,1.24542,NO,194,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.179,-4.971,2.792,,,,,,,,,,OPA,-1.59767,0.175299,0.0016145,1.24542 kka2_1:4_A110W,kka2_1:4_110,Kka2,kka2_1:4,P00552,1.24548,NO,110,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.064,-5.542,3.478,,0.175,H,A,0.46,-1.19,23.237,23.237,71.59,OHA,-1.91867,0.168804,0.00759851,1.24548 kka2_1:2_A166L,kka2_1:2_166,Kka2,kka2_1:2,P00552,1.24566,NO,166,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.407,-3.58,1.173,,0.534,.,B,0.46,1.03,23.175,23.175,71.59,HHO,-2.421,0.295029,0.00799912,1.24566 kka2_1:2_A247N,kka2_1:2_247,Kka2,kka2_1:2,P00552,1.24588,NO,247,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.459,-3.859,1.4,,1.01,S,A,0.46,0.65,0.828,,92.05,HHH,-2.197,0.295029,0.0102428,1.24588 kka2_1:4_A108T,kka2_1:4_108,Kka2,kka2_1:4,P00552,1.24591,NO,108,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.061,-2.374,0.313,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.168804,0.00751209,1.24591 kka2_1:4_Q27S,kka2_1:4_27,Kka2,kka2_1:4,P00552,1.24594,NO,27,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-1.659,-3.464,1.805,,0.608,,A,0.4,0.71,1.498,,65.53,PPP,-1.90733,0.168804,0.00595365,1.24594 kka2_1:4_I246L,kka2_1:4_246,Kka2,kka2_1:4,P00552,1.24599,NO,246,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-2.008,-2.197,0.189,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.168804,0.0139479,1.24599 kka2_1:4_D52G,kka2_1:4_52,Kka2,kka2_1:4,P00552,1.24606,NO,52,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.271,-3.385,1.114,,0.22,E,B,0.75,0.8,0.349,,71.59,PAH,-2.38367,0.168804,0.00175694,1.24606 kka2_1:2_T125N,kka2_1:2_125,Kka2,kka2_1:2,P00552,1.24607,NO,125,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.622,-3.781,1.159,,0.791,T,A,0.22,0.33,2.029,,92.05,BPH,-1.56933,0.295029,0.00821755,1.24607 beta-lactamase_0_R118H,beta-lactamase_0_118,TEM-1,beta-lactamase_0,P62593,1.24613,NO,118,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.413,-4.71,2.297,,0.457,H,A,1.2,1.39,3.961,,77.62,HBA,-1.785,0.0500837,0.00538794,1.24613 beta-lactamase_0_I140E,beta-lactamase_0_140,TEM-1,beta-lactamase_0,P62593,1.24614,NO,140,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.733,-3.925,2.192,,0.128,H,A,0.48,0.41,4.714,,73.08,PHO,-1.48733,0.0500837,0.00597777,1.24614 kka2_1:4_E230F,kka2_1:4_230,Kka2,kka2_1:4,P00552,1.24616,NO,230,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.672,-3.006,0.334,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.168804,0.00920051,1.24616 kka2_1:4_V80A,kka2_1:4_80,Kka2,kka2_1:4,P00552,1.24626,NO,80,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.144,-2.287,1.143,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.168804,0.00488211,1.24626 kka2_1:8_A166C,kka2_1:8_166,Kka2,kka2_1:8,P00552,1.24628,NO,166,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.407,-5.041,2.634,,0.534,,B,1.04,1.03,13.995,13.995,71.59,HHO,-2.421,0.100394,0.00799912,1.24628 kka2_1:8_A166C,kka2_1:8_166,Kka2,kka2_1:8,P00552,1.24628,NO,166,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.407,-5.041,2.634,,0.534,,B,1.04,1.03,13.995,13.995,71.59,HHO,-2.421,0.100394,0.00799912,1.24628 kka2_1:4_D238H,kka2_1:4_238,Kka2,kka2_1:4,P00552,1.24629,NO,238,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.83,-4.728,1.898,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.168804,0.0113863,1.24629 kka2_1:4_H8W,kka2_1:4_8,Kka2,kka2_1:4,P00552,1.24651,NO,8,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-2.759,-5.188,2.429,,,,,,,,,71.59,HBH,-2.25467,0.168804,0.00256422,1.24651 kka2_1:2_H8F,kka2_1:2_8,Kka2,kka2_1:2,P00552,1.24652,NO,8,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-2.759,-4.004,1.245,,,,,,,,,71.59,HBH,-2.25467,0.295029,0.00256422,1.24652 kka2_1:8_V242M,kka2_1:8_242,Kka2,kka2_1:8,P00552,1.24653,NO,242,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-2.687,-4.779,2.092,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.100394,0.0102575,1.24653 kka2_1:8_V242M,kka2_1:8_242,Kka2,kka2_1:8,P00552,1.24653,NO,242,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-2.687,-4.779,2.092,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.100394,0.0102575,1.24653 kka2_1:4_A166C,kka2_1:4_166,Kka2,kka2_1:4,P00552,1.24654,NO,166,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.407,-5.041,2.634,,0.534,.,B,0.46,1.03,,,71.59,HHO,-2.421,0.168804,0.00799912,1.24654 kka2_1:4_R177S,kka2_1:4_177,Kka2,kka2_1:4,P00552,1.24663,NO,177,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.282,-2.536,0.254,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.168804,0.00768224,1.24663 kka2_1:8_V83K,kka2_1:8_83,Kka2,kka2_1:8,P00552,1.24674,NO,83,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-2.567,-3.653,1.086,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.100394,0.00650486,1.24674 kka2_1:8_V83K,kka2_1:8_83,Kka2,kka2_1:8,P00552,1.24674,NO,83,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-2.567,-3.653,1.086,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.100394,0.00650486,1.24674 kka2_1:2_A79E,kka2_1:2_79,Kka2,kka2_1:2,P00552,1.24694,NO,79,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.368,-2.303,-0.065,,0.563,.,B,0.46,-0.43,0.475,,71.59,HHH,-1.752,0.295029,0.00664821,1.24694 kka2_1:8_K175T,kka2_1:8_175,Kka2,kka2_1:8,P00552,1.24702,NO,175,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-2.897,-2.9,0.003,,0.579,H,A,2.34,0.51,15.316,15.316,71.59,HBH,-1.82333,0.100394,0.00693093,1.24702 kka2_1:8_K175T,kka2_1:8_175,Kka2,kka2_1:8,P00552,1.24702,NO,175,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-2.897,-2.9,0.003,,0.579,H,A,2.34,0.51,15.316,15.316,71.59,HBH,-1.82333,0.100394,0.00693093,1.24702 beta-lactamase_0_D113E,beta-lactamase_0_113,TEM-1,beta-lactamase_0,P62593,1.24703,NO,113,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.829,-2.32,0.491,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.0500837,0.00474112,1.24703 kka2_1:4_A166R,kka2_1:4_166,Kka2,kka2_1:4,P00552,1.24703,NO,166,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.407,-3.179,0.772,,0.534,.,B,0.46,1.03,,,71.59,HHO,-2.421,0.168804,0.00799912,1.24703 kka2_1:8_A14H,kka2_1:8_14,Kka2,kka2_1:8,P00552,1.24721,NO,14,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.837,-4.803,2.966,,0.728,G,A,0.46,0.7,,,71.59,HHH,-1.82567,0.100394,0.00706614,1.24721 kka2_1:8_A14H,kka2_1:8_14,Kka2,kka2_1:8,P00552,1.24721,NO,14,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.837,-4.803,2.966,,0.728,G,A,0.46,0.7,,,71.59,HHH,-1.82567,0.100394,0.00706614,1.24721 kka2_1:2_Q61E,kka2_1:2_61,Kka2,kka2_1:2,P00552,1.2473,NO,61,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.982,-2.773,-0.209,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.295029,0.00612092,1.2473 kka2_1:8_V153F,kka2_1:8_153,Kka2,kka2_1:8,P00552,1.24733,NO,153,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.092,-3.89,2.798,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.100394,0.00501119,1.24733 kka2_1:8_V153F,kka2_1:8_153,Kka2,kka2_1:8,P00552,1.24733,NO,153,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.092,-3.89,2.798,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.100394,0.00501119,1.24733 kka2_1:4_A14V,kka2_1:4_14,Kka2,kka2_1:4,P00552,1.24738,NO,14,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.837,-2.963,1.126,,0.728,G,A,0.46,0.7,0.36,,71.59,HHH,-1.82567,0.168804,0.00706614,1.24738 beta-lactamase_0_I285S,beta-lactamase_0_285,TEM-1,beta-lactamase_0,P62593,1.2474,NO,285,I,S,IS,Hydrophobic,Polar,6.02,5.68,-0.34,142,131,105,-26,166.7,89,-77.7,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.0500837,0.101555,1.2474 kka2_1:4_Q100M,kka2_1:4_100,Kka2,kka2_1:4,P00552,1.24754,NO,100,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.77,-3.639,0.869,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.168804,0.0066405,1.24754 kka2_1:4_R143C,kka2_1:4_143,Kka2,kka2_1:4,P00552,1.24763,NO,143,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.525,-5.079,2.554,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.168804,0.00662247,1.24763 kka2_1:2_S104T,kka2_1:2_104,Kka2,kka2_1:2,P00552,1.24767,NO,104,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-1.436,-2.284,0.848,,0.536,T,A,0.27,-1.11,5.49,,63.64,HPP,-1.91433,0.295029,0.00555207,1.24767 kka2_1:4_L7I,kka2_1:4_7,Kka2,kka2_1:4,P00552,1.24768,NO,7,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.926,-3.353,1.427,,,,,,,3.012,,71.59,OHB,-2.12333,0.168804,0.00269456,1.24768 kka2_1:4_H8Q,kka2_1:4_8,Kka2,kka2_1:4,P00552,1.24773,NO,8,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-2.759,-2.66,-0.099,,,,,,,,,71.59,HBH,-2.25467,0.168804,0.00256422,1.24773 kka2_1:4_Q155W,kka2_1:4_155,Kka2,kka2_1:4,P00552,1.24794,NO,155,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.606,-5.444,2.838,,0.525,T,A,0.64,1.49,1.592,,63.64,APA,-1.726,0.168804,0.00641853,1.24794 kka2_1:4_A166I,kka2_1:4_166,Kka2,kka2_1:4,P00552,1.24797,NO,166,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.407,-3.972,1.565,,0.534,.,B,0.46,1.03,,,71.59,HHO,-2.421,0.168804,0.00799912,1.24797 kka2_1:8_R239E,kka2_1:8_239,Kka2,kka2_1:8,P00552,1.24797,NO,239,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.949,-2.985,0.036,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.100394,0.00835326,1.24797 kka2_1:8_R239E,kka2_1:8_239,Kka2,kka2_1:8,P00552,1.24797,NO,239,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.949,-2.985,0.036,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.100394,0.00835326,1.24797 kka2_1:4_E160V,kka2_1:4_160,Kka2,kka2_1:4,P00552,1.24804,NO,160,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.683,-3.733,2.05,,0.989,G,A,1.04,2.28,2.531,,71.59,AAA,-1.36133,0.168804,0.00935762,1.24804 beta-lactamase_0_L219D,beta-lactamase_0_219,TEM-1,beta-lactamase_0,P62593,1.24805,NO,219,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.313,-4.126,2.813,,,I,A,0.55,-0.51,6.513,6.513,74.48,HHB,-1.21533,0.0500837,0.00664345,1.24805 kka2_1:2_C77T,kka2_1:2_77,Kka2,kka2_1:2,P00552,1.2482,NO,77,C,T,CT,Special,Polar,5.07,5.6,0.53,149,121,119,-2,108.5,116.1,7.6,-1.477,-3.496,2.019,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.295029,0.00441216,1.2482 kka2_1:8_L7A,kka2_1:8_7,Kka2,kka2_1:8,P00552,1.24831,NO,7,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.926,-3.033,1.107,,,,,,,,,71.59,OHB,-2.12333,0.100394,0.00269456,1.24831 kka2_1:8_L7A,kka2_1:8_7,Kka2,kka2_1:8,P00552,1.24831,NO,7,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.926,-3.033,1.107,,,,,,,,,71.59,OHB,-2.12333,0.100394,0.00269456,1.24831 kka2_1:2_R38K,kka2_1:2_38,Kka2,kka2_1:2,P00552,1.24853,NO,38,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.207,-3.15,1.943,,0.355,E,B,1.2,-1.13,6.872,6.872,52.27,HBH,-1.28567,0.295029,0.00372499,1.24853 kka2_1:2_A25M,kka2_1:2_25,Kka2,kka2_1:2,P00552,1.24856,NO,25,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.496,-3.529,1.033,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.295029,0.00595636,1.24856 beta-lactamase_0_T107E,beta-lactamase_0_107,TEM-1,beta-lactamase_0,P62593,1.24857,NO,107,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.117,-3.43,2.313,,,G,A,0.22,-0.06,3.73,,67.83,HPA,-1.265,0.0500837,0.00239347,1.24857 kka2_1:8_A172C,kka2_1:8_172,Kka2,kka2_1:8,P00552,1.24861,NO,172,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.757,-5.069,3.312,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.100394,0.0079265,1.24861 kka2_1:8_A172C,kka2_1:8_172,Kka2,kka2_1:8,P00552,1.24861,NO,172,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.757,-5.069,3.312,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.100394,0.0079265,1.24861 kka2_1:2_S54C,kka2_1:2_54,Kka2,kka2_1:2,P00552,1.24865,NO,54,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.471,-4.966,2.495,,0.408,S,b,0.27,1.01,0.393,,71.59,HPO,-2.259,0.295029,0.00782867,1.24865 kka2_1:4_E230Y,kka2_1:4_230,Kka2,kka2_1:4,P00552,1.24865,NO,230,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.672,-2.09,-0.582,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.168804,0.00920051,1.24865 kka2_1:8_I2V,kka2_1:8_2,Kka2,kka2_1:8,P00552,1.24869,NO,2,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.787,-1.838,0.051,,,,,,,,,71.59,HHA,-1.92433,0.100394,0.00246644,1.24869 kka2_1:8_I2V,kka2_1:8_2,Kka2,kka2_1:8,P00552,1.24869,NO,2,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.787,-1.838,0.051,,,,,,,,,71.59,HHA,-1.92433,0.100394,0.00246644,1.24869 kka2_1:4_G6H,kka2_1:4_6,Kka2,kka2_1:4,P00552,1.24875,NO,6,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.685,-4.557,2.872,,,,,,,,,71.59,AOH,-1.639,0.168804,0.00204693,1.24875 kka2_1:2_L19F,kka2_1:2_19,Kka2,kka2_1:2,P00552,1.24876,NO,19,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.254,-2.137,0.883,,0.08,T,A,0.55,-0.26,17.165,17.165,65.53,BHH,-2.221,0.295029,0.00620703,1.24876 kka2_1:4_Q252R,kka2_1:4_252,Kka2,kka2_1:4,P00552,1.24878,NO,252,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.63,-2.449,-0.181,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.168804,0.0121001,1.24878 kka2_1:8_E235Y,kka2_1:8_235,Kka2,kka2_1:8,P00552,1.24899,NO,235,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.955,-4.43,2.475,,0.631,H,A,1.52,0.12,,,65.53,OAH,-2.07267,0.100394,0.0102806,1.24899 kka2_1:8_E235Y,kka2_1:8_235,Kka2,kka2_1:8,P00552,1.24899,NO,235,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.955,-4.43,2.475,,0.631,H,A,1.52,0.12,,,65.53,OAH,-2.07267,0.100394,0.0102806,1.24899 kka2_1:8_A247N,kka2_1:8_247,Kka2,kka2_1:8,P00552,1.24902,NO,247,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.459,-3.859,1.4,,1.01,S,A,0.46,0.65,18.904,18.904,92.05,HHH,-2.197,0.100394,0.0102428,1.24902 kka2_1:8_A247N,kka2_1:8_247,Kka2,kka2_1:8,P00552,1.24902,NO,247,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.459,-3.859,1.4,,1.01,S,A,0.46,0.65,18.904,18.904,92.05,HHH,-2.197,0.100394,0.0102428,1.24902 kka2_1:4_D154Q,kka2_1:4_154,Kka2,kka2_1:4,P00552,1.24905,NO,154,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-0.876,-3.709,2.833,,0.457,,b,0.29,1.48,15.641,15.641,52.65,HAP,-1.52467,0.168804,0.00292633,1.24905 kka2_1:8_D33G,kka2_1:8_33,Kka2,kka2_1:8,P00552,1.24907,NO,33,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.186,-2.077,-0.109,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.100394,0.00633568,1.24907 kka2_1:8_D33G,kka2_1:8_33,Kka2,kka2_1:8,P00552,1.24907,NO,33,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.186,-2.077,-0.109,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.100394,0.00633568,1.24907 kka2_1:2_G181W,kka2_1:2_181,Kka2,kka2_1:2,P00552,1.24915,NO,181,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-2.698,-5.561,2.863,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.295029,0.00728319,1.24915 beta-lactamase_0_T147I,beta-lactamase_0_147,TEM-1,beta-lactamase_0,P62593,1.24916,NO,147,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.149,-2.792,1.643,,0.281,H,A,0.22,-0.68,3.487,,64.34,HPH,-1.456,0.0500837,0.00226017,1.24916 kka2_1:2_A176H,kka2_1:2_176,Kka2,kka2_1:2,P00552,1.24927,NO,176,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.621,-4.691,3.07,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.295029,0.0083587,1.24927 beta-lactamase_0_E164N,beta-lactamase_0_164,TEM-1,beta-lactamase_0,P62593,1.24929,NO,164,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-0.948,-3.497,2.549,,0.011,T,B,1.04,-0.4,1.011,,64.69,HAO,-1.388,0.0500837,0.00137286,1.24929 kka2_1:4_E199K,kka2_1:4_199,Kka2,kka2_1:4,P00552,1.24931,NO,199,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.234,-3.055,0.821,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.168804,0.00854122,1.24931 kka2_1:2_D5H,kka2_1:2_5,Kka2,kka2_1:2,P00552,1.2495,NO,5,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.306,-4.185,2.879,,,,,,,,,71.59,PAO,-1.784,0.295029,0.00222864,1.2495 beta-lactamase_0_K190C,beta-lactamase_0_190,TEM-1,beta-lactamase_0,P62593,1.24954,NO,190,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.994,-5.082,3.088,,0.371,H,A,2.34,0.16,16.606,16.606,77.62,BBH,-1.64167,0.0500837,0.00574527,1.24954 kka2_1:4_G6F,kka2_1:4_6,Kka2,kka2_1:4,P00552,1.24962,NO,6,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.685,-4.169,2.484,,,,,,,,,71.59,AOH,-1.639,0.168804,0.00204693,1.24962 kka2_1:2_A13I,kka2_1:2_13,Kka2,kka2_1:2,P00552,1.24972,NO,13,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.248,-3.155,0.907,,0.689,G,A,0.46,0.99,,,92.05,OHH,-1.646,0.295029,0.00784241,1.24972 kka2_1:4_G234P,kka2_1:4_234,Kka2,kka2_1:4,P00552,1.24979,NO,234,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-2.9,-2.731,-0.169,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.168804,0.00984449,1.24979 kka2_1:4_V84A,kka2_1:4_84,Kka2,kka2_1:4,P00552,1.24979,NO,84,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-2.279,-1.994,-0.285,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.168804,0.00724019,1.24979 kka2_1:4_S114C,kka2_1:4_114,Kka2,kka2_1:4,P00552,1.24988,NO,114,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.527,-5.142,2.615,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.168804,0.00705262,1.24988 beta-lactamase_0_V214W,beta-lactamase_0_214,TEM-1,beta-lactamase_0,P62593,1.25,NO,214,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.299,-5.33,4.031,,0.375,S,A,0.44,-0.44,3.712,,74.48,BHH,-1.53733,0.0500837,0.00628442,1.25 kka2_1:8_E199N,kka2_1:8_199,Kka2,kka2_1:8,P00552,1.25003,NO,199,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.234,-3.807,1.573,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.100394,0.00854122,1.25003 kka2_1:8_E199N,kka2_1:8_199,Kka2,kka2_1:8,P00552,1.25003,NO,199,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.234,-3.807,1.573,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.100394,0.00854122,1.25003 kka2_1:4_A176L,kka2_1:4_176,Kka2,kka2_1:4,P00552,1.25004,NO,176,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.621,-3.555,1.934,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.168804,0.0083587,1.25004 kka2_1:4_E17Q,kka2_1:4_17,Kka2,kka2_1:4,P00552,1.25018,NO,17,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.154,-2.533,0.379,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.168804,0.00688738,1.25018 beta-lactamase_0_A77H,beta-lactamase_0_77,TEM-1,beta-lactamase_0,P62593,1.2503,NO,77,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.234,-3.165,1.931,,0.039,H,A,0.46,-0.56,2.591,,64.34,OHH,-1.294,0.0500837,0.00282362,1.2503 kka2_1:2_R18Y,kka2_1:2_18,Kka2,kka2_1:2,P00552,1.25047,NO,18,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.055,-3.413,1.358,,0.474,T,A,1.2,0.54,8.405,8.405,71.59,ABH,-1.821,0.295029,0.00724065,1.25047 kka2_1:4_S54M,kka2_1:4_54,Kka2,kka2_1:4,P00552,1.25047,NO,54,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.471,-4.618,2.147,,0.408,S,b,0.27,1.01,17.332,17.332,71.59,HPO,-2.259,0.168804,0.00782867,1.25047 kka2_1:2_V83C,kka2_1:2_83,Kka2,kka2_1:2,P00552,1.25054,NO,83,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-2.567,-5.124,2.557,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.295029,0.00650486,1.25054 kka2_1:8_S40C,kka2_1:8_40,Kka2,kka2_1:8,P00552,1.25065,NO,40,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.645,-3.648,1.003,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.100394,0.00693477,1.25065 kka2_1:8_S40C,kka2_1:8_40,Kka2,kka2_1:8,P00552,1.25065,NO,40,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.645,-3.648,1.003,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.100394,0.00693477,1.25065 kka2_1:2_E3P,kka2_1:2_3,Kka2,kka2_1:2,P00552,1.25068,NO,3,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.199,-3.691,1.492,,,,,,,7.22,,92.05,HAP,-2.11567,0.295029,0.00267607,1.25068 kka2_1:4_T28M,kka2_1:4_28,Kka2,kka2_1:4,P00552,1.2507,NO,28,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.883,-3.567,1.684,,0.353,S,B,0.82,2.02,4.415,,63.64,PPH,-1.74467,0.168804,0.00743084,1.2507 kka2_1:2_A248V,kka2_1:2_248,Kka2,kka2_1:2,P00552,1.25077,NO,248,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.124,-2.592,0.468,,0.825,S,b,0.46,0.46,,,92.05,HHO,-2.15,0.295029,0.0125484,1.25077 kka2_1:8_F20H,kka2_1:8_20,Kka2,kka2_1:8,P00552,1.25081,NO,20,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-3.354,-4.805,1.451,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.100394,0.00701744,1.25081 kka2_1:8_F20H,kka2_1:8_20,Kka2,kka2_1:8,P00552,1.25081,NO,20,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-3.354,-4.805,1.451,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.100394,0.00701744,1.25081 kka2_1:8_E160Y,kka2_1:8_160,Kka2,kka2_1:8,P00552,1.25086,NO,160,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.683,-4.448,2.765,,0.989,G,A,1.04,2.28,2.164,,71.59,AAA,-1.36133,0.100394,0.00935762,1.25086 kka2_1:8_E160Y,kka2_1:8_160,Kka2,kka2_1:8,P00552,1.25086,NO,160,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.683,-4.448,2.765,,0.989,G,A,1.04,2.28,2.164,,71.59,AAA,-1.36133,0.100394,0.00935762,1.25086 kka2_1:4_A229R,kka2_1:4_229,Kka2,kka2_1:4,P00552,1.25093,NO,229,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.739,-2.242,0.503,,0.32,H,A,0.46,-0.7,1.689,,63.64,HHA,-1.851,0.168804,0.00942138,1.25093 kka2_1:4_T130A,kka2_1:4_130,Kka2,kka2_1:4,P00552,1.25102,NO,130,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.392,-1.951,-0.441,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.168804,0.00804204,1.25102 kka2_1:2_A168M,kka2_1:2_168,Kka2,kka2_1:2,P00552,1.25108,NO,168,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.989,-4.833,2.844,,0.67,H,A,0.46,0.15,25.546,25.546,64.39,OHA,-2.12933,0.295029,0.00806773,1.25108 kka2_1:4_V153F,kka2_1:4_153,Kka2,kka2_1:4,P00552,1.25115,NO,153,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.092,-3.89,2.798,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.168804,0.00501119,1.25115 kka2_1:8_D154K,kka2_1:8_154,Kka2,kka2_1:8,P00552,1.25116,NO,154,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.876,-3.46,2.584,,0.457,,b,0.29,1.48,0.844,,52.65,HAP,-1.52467,0.100394,0.00292633,1.25116 kka2_1:8_D154K,kka2_1:8_154,Kka2,kka2_1:8,P00552,1.25116,NO,154,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.876,-3.46,2.584,,0.457,,b,0.29,1.48,0.844,,52.65,HAP,-1.52467,0.100394,0.00292633,1.25116 kka2_1:8_M178Y,kka2_1:8_178,Kka2,kka2_1:8,P00552,1.2512,NO,178,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-3.206,-4.367,1.161,,0.554,,b,1.59,0.68,13.268,13.268,71.59,BHO,-2.154,0.100394,0.00717253,1.2512 kka2_1:8_M178Y,kka2_1:8_178,Kka2,kka2_1:8,P00552,1.2512,NO,178,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-3.206,-4.367,1.161,,0.554,,b,1.59,0.68,13.268,13.268,71.59,BHO,-2.154,0.100394,0.00717253,1.2512 kka2_1:4_Q252M,kka2_1:4_252,Kka2,kka2_1:4,P00552,1.25128,NO,252,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.63,-4.83,2.2,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.168804,0.0121001,1.25128 kka2_1:8_Y218M,kka2_1:8_218,Kka2,kka2_1:8,P00552,1.25135,NO,218,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-1.438,-4.695,3.257,,0.122,H,A,1.25,-0.69,2.923,,56.06,BHP,-1.17533,0.100394,0.0126098,1.25135 kka2_1:8_Y218M,kka2_1:8_218,Kka2,kka2_1:8,P00552,1.25135,NO,218,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-1.438,-4.695,3.257,,0.122,H,A,1.25,-0.69,2.923,,56.06,BHP,-1.17533,0.100394,0.0126098,1.25135 beta-lactamase_0_E272D,beta-lactamase_0_272,TEM-1,beta-lactamase_0,P62593,1.25137,NO,272,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.0500837,0.00545371,1.25137 kka2_1:8_E3I,kka2_1:8_3,Kka2,kka2_1:8,P00552,1.25151,NO,3,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.199,-3.832,1.633,,,,,,,7.22,,92.05,HAP,-2.11567,0.100394,0.00267607,1.25151 kka2_1:8_E3I,kka2_1:8_3,Kka2,kka2_1:8,P00552,1.25151,NO,3,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.199,-3.832,1.633,,,,,,,7.22,,92.05,HAP,-2.11567,0.100394,0.00267607,1.25151 kka2_1:8_A35K,kka2_1:8_35,Kka2,kka2_1:8,P00552,1.25171,NO,35,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.127,-3.623,1.496,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.100394,0.00630016,1.25171 kka2_1:8_A35K,kka2_1:8_35,Kka2,kka2_1:8,P00552,1.25171,NO,35,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.127,-3.623,1.496,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.100394,0.00630016,1.25171 kka2_1:4_D134K,kka2_1:4_134,Kka2,kka2_1:4,P00552,1.25174,NO,134,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.969,-3.503,2.534,,0.421,B,B,0.75,0.31,0.733,,49.62,HAB,-1.057,0.168804,0.00270812,1.25174 kka2_1:2_A172K,kka2_1:2_172,Kka2,kka2_1:2,P00552,1.25175,NO,172,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.757,-3.042,1.285,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.295029,0.0079265,1.25175 beta-lactamase_0_I258Q,beta-lactamase_0_258,TEM-1,beta-lactamase_0,P62593,1.25176,NO,258,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.0500837,0.007931,1.25176 kka2_1:4_L243A,kka2_1:4_243,Kka2,kka2_1:4,P00552,1.25188,NO,243,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-2.651,-2.102,-0.549,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.168804,0.00884927,1.25188 kka2_1:8_D250E,kka2_1:8_250,Kka2,kka2_1:8,P00552,1.25196,NO,250,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.015,-2.129,1.114,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.100394,0.0177103,1.25196 kka2_1:8_D250E,kka2_1:8_250,Kka2,kka2_1:8,P00552,1.25196,NO,250,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.015,-2.129,1.114,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.100394,0.0177103,1.25196 kka2_1:4_K138R,kka2_1:4_138,Kka2,kka2_1:4,P00552,1.2522,NO,138,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-2.5,-3.18,0.68,,0.594,H,A,1.3,0.98,21.267,21.267,71.59,HBB,-2.48833,0.168804,0.00628542,1.2522 kka2_1:8_D23N,kka2_1:8_23,Kka2,kka2_1:8,P00552,1.25227,NO,23,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.459,-3.82,1.361,,0.695,E,B,0.75,-0.65,,,65.53,HAH,-1.94033,0.100394,0.007195,1.25227 kka2_1:8_D23N,kka2_1:8_23,Kka2,kka2_1:8,P00552,1.25227,NO,23,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.459,-3.82,1.361,,0.695,E,B,0.75,-0.65,,,65.53,HAH,-1.94033,0.100394,0.007195,1.25227 beta-lactamase_0_R41K,beta-lactamase_0_41,TEM-1,beta-lactamase_0,P62593,1.2523,NO,41,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-0.942,-2.85,1.908,,0.321,E,B,1.2,-0.07,2.68,,65.03,HBH,-1.30267,0.0500837,0.00123327,1.2523 kka2_1:4_K175V,kka2_1:4_175,Kka2,kka2_1:4,P00552,1.25251,NO,175,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-2.897,-2.802,-0.095,,0.579,H,A,1.3,0.51,15.629,15.629,71.59,HBH,-1.82333,0.168804,0.00693093,1.25251 kka2_1:4_V242G,kka2_1:4_242,Kka2,kka2_1:4,P00552,1.25253,NO,242,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-2.687,-3.538,0.851,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.168804,0.0102575,1.25253 kka2_1:2_A9M,kka2_1:2_9,Kka2,kka2_1:2,P00552,1.25262,NO,9,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.079,-2.864,0.785,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.295029,0.00273264,1.25262 kka2_1:8_A247L,kka2_1:8_247,Kka2,kka2_1:8,P00552,1.25285,NO,247,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.459,-2.722,0.263,,1.01,S,A,0.46,0.65,18.904,18.904,92.05,HHH,-2.197,0.100394,0.0102428,1.25285 kka2_1:8_A247L,kka2_1:8_247,Kka2,kka2_1:8,P00552,1.25285,NO,247,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.459,-2.722,0.263,,1.01,S,A,0.46,0.65,18.904,18.904,92.05,HHH,-2.197,0.100394,0.0102428,1.25285 kka2_1:8_S11Q,kka2_1:8_11,Kka2,kka2_1:8,P00552,1.25295,NO,11,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.322,-3.989,1.667,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.100394,0.00381691,1.25295 kka2_1:8_S11Q,kka2_1:8_11,Kka2,kka2_1:8,P00552,1.25295,NO,11,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.322,-3.989,1.667,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.100394,0.00381691,1.25295 kka2_1:2_A14K,kka2_1:2_14,Kka2,kka2_1:2,P00552,1.25307,NO,14,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.837,-2.596,0.759,,0.728,G,A,0.46,0.7,0.36,,71.59,HHH,-1.82567,0.295029,0.00706614,1.25307 beta-lactamase_0_I285V,beta-lactamase_0_285,TEM-1,beta-lactamase_0,P62593,1.25316,NO,285,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.0500837,0.101555,1.25316 kka2_1:8_A248W,kka2_1:8_248,Kka2,kka2_1:8,P00552,1.25333,NO,248,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.124,-5.601,3.477,,0.825,S,b,1.04,0.46,11.329,11.329,92.05,HHO,-2.15,0.100394,0.0125484,1.25333 kka2_1:8_A248W,kka2_1:8_248,Kka2,kka2_1:8,P00552,1.25333,NO,248,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.124,-5.601,3.477,,0.825,S,b,1.04,0.46,11.329,11.329,92.05,HHO,-2.15,0.100394,0.0125484,1.25333 kka2_1:8_W24A,kka2_1:8_24,Kka2,kka2_1:8,P00552,1.25335,NO,24,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-1.779,-3.385,1.606,,0.477,E,B,1.51,-0.21,2.503,,56.06,AHH,-2.24467,0.100394,0.00631564,1.25335 kka2_1:8_W24A,kka2_1:8_24,Kka2,kka2_1:8,P00552,1.25335,NO,24,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-1.779,-3.385,1.606,,0.477,E,B,1.51,-0.21,2.503,,56.06,AHH,-2.24467,0.100394,0.00631564,1.25335 kka2_1:4_P76E,kka2_1:4_76,Kka2,kka2_1:4,P00552,1.2534,NO,76,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.449,-2.905,1.456,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.168804,0.00625685,1.2534 kka2_1:2_A168G,kka2_1:2_168,Kka2,kka2_1:2,P00552,1.25343,NO,168,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.989,-2.951,0.962,,0.67,H,A,0.46,0.15,25.546,25.546,64.39,OHA,-2.12933,0.295029,0.00806773,1.25343 WW_domain_D194K,WW_domain_194,Yap65,WW_domain,P46937,1.25344,NO,194,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.536,-3.286,1.75,5.95614,,,,,,1.948,,74.4,HAP,-1.78933,0.153962,0.00483742,1.25344 kka2_1:8_L47F,kka2_1:8_47,Kka2,kka2_1:8,P00552,1.2535,NO,47,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.265,-2.523,1.258,,0.139,E,B,1.59,-0.86,5.086,,63.26,HHH,-1.77933,0.100394,0.00509386,1.2535 kka2_1:8_L47F,kka2_1:8_47,Kka2,kka2_1:8,P00552,1.2535,NO,47,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.265,-2.523,1.258,,0.139,E,B,1.59,-0.86,5.086,,63.26,HHH,-1.77933,0.100394,0.00509386,1.2535 kka2_1:2_S40H,kka2_1:2_40,Kka2,kka2_1:2,P00552,1.25362,NO,40,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.645,-3.006,0.361,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.295029,0.00693477,1.25362 kka2_1:2_L7P,kka2_1:2_7,Kka2,kka2_1:2,P00552,1.25383,NO,7,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.926,-3.817,1.891,,,,,,,3.012,,71.59,OHB,-2.12333,0.295029,0.00269456,1.25383 kka2_1:8_Q61P,kka2_1:8_61,Kka2,kka2_1:8,P00552,1.2539,NO,61,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.982,-1.818,-1.164,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.100394,0.00612092,1.2539 kka2_1:8_Q61P,kka2_1:8_61,Kka2,kka2_1:8,P00552,1.2539,NO,61,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.982,-1.818,-1.164,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.100394,0.00612092,1.2539 kka2_1:8_A13M,kka2_1:8_13,Kka2,kka2_1:8,P00552,1.25398,NO,13,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.248,-3.735,1.487,,0.689,G,A,1.04,0.99,14.966,14.966,92.05,OHH,-1.646,0.100394,0.00784241,1.25398 kka2_1:8_A13M,kka2_1:8_13,Kka2,kka2_1:8,P00552,1.25398,NO,13,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.248,-3.735,1.487,,0.689,G,A,1.04,0.99,14.966,14.966,92.05,OHH,-1.646,0.100394,0.00784241,1.25398 kka2_1:8_V49I,kka2_1:8_49,Kka2,kka2_1:8,P00552,1.25399,NO,49,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.614,-2.255,0.641,,,E,B,1.48,-0.77,1.31,,64.39,HHB,-1.3,0.100394,0.00615685,1.25399 kka2_1:8_V49I,kka2_1:8_49,Kka2,kka2_1:8,P00552,1.25399,NO,49,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.614,-2.255,0.641,,,E,B,1.48,-0.77,1.31,,64.39,HHB,-1.3,0.100394,0.00615685,1.25399 kka2_1:8_R18I,kka2_1:8_18,Kka2,kka2_1:8,P00552,1.25405,NO,18,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.055,-3.256,1.201,,0.474,T,A,1.2,0.54,19.629,19.629,71.59,ABH,-1.821,0.100394,0.00724065,1.25405 kka2_1:8_R18I,kka2_1:8_18,Kka2,kka2_1:8,P00552,1.25405,NO,18,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.055,-3.256,1.201,,0.474,T,A,1.2,0.54,19.629,19.629,71.59,ABH,-1.821,0.100394,0.00724065,1.25405 kka2_1:4_G6D,kka2_1:4_6,Kka2,kka2_1:4,P00552,1.25425,NO,6,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.685,-3.441,1.756,,,,,,,,,71.59,AOH,-1.639,0.168804,0.00204693,1.25425 kka2_1:4_G21S,kka2_1:4_21,Kka2,kka2_1:4,P00552,1.25426,NO,21,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.368,-2.431,1.063,,0.586,T,l,0.75,-0.75,3.075,,71.59,HOH,-2.10167,0.168804,0.00709648,1.25426 kka2_1:8_S54Y,kka2_1:8_54,Kka2,kka2_1:8,P00552,1.25431,NO,54,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.471,-4.321,1.85,,0.408,S,b,0.77,1.01,13.679,13.679,71.59,HPO,-2.259,0.100394,0.00782867,1.25431 kka2_1:8_S54Y,kka2_1:8_54,Kka2,kka2_1:8,P00552,1.25431,NO,54,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.471,-4.321,1.85,,0.408,S,b,0.77,1.01,13.679,13.679,71.59,HPO,-2.259,0.100394,0.00782867,1.25431 kka2_1:4_Q4D,kka2_1:4_4,Kka2,kka2_1:4,P00552,1.25432,NO,4,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.361,-3.094,0.733,,,,,,,2.026,,71.59,APA,-1.95533,0.168804,0.00239179,1.25432 kka2_1:4_V214I,kka2_1:4_214,Kka2,kka2_1:4,P00552,1.25439,NO,214,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.261,-1.849,0.588,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.168804,0.00692782,1.25439 kka2_1:8_M178F,kka2_1:8_178,Kka2,kka2_1:8,P00552,1.25448,NO,178,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-3.206,-4.351,1.145,,0.554,,b,1.59,0.68,13.268,13.268,71.59,BHO,-2.154,0.100394,0.00717253,1.25448 kka2_1:8_M178F,kka2_1:8_178,Kka2,kka2_1:8,P00552,1.25448,NO,178,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-3.206,-4.351,1.145,,0.554,,b,1.59,0.68,13.268,13.268,71.59,BHO,-2.154,0.100394,0.00717253,1.25448 kka2_1:4_A166N,kka2_1:4_166,Kka2,kka2_1:4,P00552,1.25456,NO,166,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.407,-3.048,0.641,,0.534,.,B,0.46,1.03,,,71.59,HHO,-2.421,0.168804,0.00799912,1.25456 beta-lactamase_0_T147V,beta-lactamase_0_147,TEM-1,beta-lactamase_0,P62593,1.25459,NO,147,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.149,-3.22,2.071,,0.281,H,A,0.22,-0.68,3.487,,64.34,HPH,-1.456,0.0500837,0.00226017,1.25459 beta-lactamase_0_I93E,beta-lactamase_0_93,TEM-1,beta-lactamase_0,P62593,1.25461,NO,93,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.401,-3.886,2.485,,0.128,E,B,0.48,0.44,1.266,,67.83,BHB,-1.873,0.0500837,0.00527066,1.25461 kka2_1:2_D238N,kka2_1:2_238,Kka2,kka2_1:2,P00552,1.25466,NO,238,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.83,-3.158,0.328,,0.604,H,A,0.75,-0.33,22.789,22.789,92.05,HAB,-2.633,0.295029,0.0113863,1.25466 kka2_1:4_E111Q,kka2_1:4_111,Kka2,kka2_1:4,P00552,1.25474,NO,111,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.28,-2.347,0.067,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.168804,0.00746789,1.25474 kka2_1:8_A56Q,kka2_1:8_56,Kka2,kka2_1:8,P00552,1.25478,NO,56,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.083,-4.08,1.997,,0.796,T,A,0.46,1.39,10.511,,71.59,OHH,-1.86867,0.100394,0.00717715,1.25478 kka2_1:8_A56Q,kka2_1:8_56,Kka2,kka2_1:8,P00552,1.25478,NO,56,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.083,-4.08,1.997,,0.796,T,A,0.46,1.39,10.511,,71.59,OHH,-1.86867,0.100394,0.00717715,1.25478 kka2_1:2_Q219T,kka2_1:2_219,Kka2,kka2_1:2,P00552,1.25479,NO,219,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-0.93,-3.473,2.543,,0.088,H,A,0.4,-0.85,1.917,,50,HPA,-1.05167,0.295029,0.00237913,1.25479 kka2_1:4_A41M,kka2_1:4_41,Kka2,kka2_1:4,P00552,1.25483,NO,41,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.879,-3.613,1.734,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.168804,0.00543332,1.25483 kka2_1:8_I2M,kka2_1:8_2,Kka2,kka2_1:8,P00552,1.25484,NO,2,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.787,-3.979,2.192,,,,,,,,,71.59,HHA,-1.92433,0.100394,0.00246644,1.25484 kka2_1:8_I2M,kka2_1:8_2,Kka2,kka2_1:8,P00552,1.25484,NO,2,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.787,-3.979,2.192,,,,,,,,,71.59,HHA,-1.92433,0.100394,0.00246644,1.25484 kka2_1:4_A13R,kka2_1:4_13,Kka2,kka2_1:4,P00552,1.25485,NO,13,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.248,-2.994,0.746,,0.689,G,A,0.46,0.99,,,92.05,OHH,-1.646,0.168804,0.00784241,1.25485 kka2_1:4_Q26F,kka2_1:4_26,Kka2,kka2_1:4,P00552,1.25489,NO,26,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.18,-4.426,2.246,,0.448,E,B,0.4,0.44,5.022,,92.05,HPP,-2.11167,0.168804,0.00708962,1.25489 kka2_1:2_R173W,kka2_1:2_173,Kka2,kka2_1:2,P00552,1.25501,NO,173,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.407,-3.224,0.817,,0.308,H,A,0.16,-0.13,15.389,15.389,65.53,HBH,-1.70533,0.295029,0.00784999,1.25501 kka2_1:8_R177G,kka2_1:8_177,Kka2,kka2_1:8,P00552,1.25507,NO,177,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.282,-2.48,0.198,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.100394,0.00768224,1.25507 kka2_1:8_R177G,kka2_1:8_177,Kka2,kka2_1:8,P00552,1.25507,NO,177,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.282,-2.48,0.198,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.100394,0.00768224,1.25507 kka2_1:4_D180R,kka2_1:4_180,Kka2,kka2_1:4,P00552,1.25518,NO,180,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.416,-2.973,0.557,,1.03,S,a,0.29,1.5,14.668,14.668,71.59,OAO,-2.02933,0.168804,0.00756412,1.25518 kka2_1:2_A65K,kka2_1:2_65,Kka2,kka2_1:2,P00552,1.25531,NO,65,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.744,-3.037,1.293,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.295029,0.00709258,1.25531 kka2_1:4_I141C,kka2_1:4_141,Kka2,kka2_1:4,P00552,1.25531,NO,141,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.495,-4.812,3.317,,0.068,H,A,0.48,-0.01,2.144,,92.05,BHA,-1.689,0.168804,0.00744745,1.25531 kka2_1:8_A166W,kka2_1:8_166,Kka2,kka2_1:8,P00552,1.25536,NO,166,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.407,-5.55,3.143,,0.534,,B,1.04,1.03,13.995,13.995,71.59,HHO,-2.421,0.100394,0.00799912,1.25536 kka2_1:8_A166W,kka2_1:8_166,Kka2,kka2_1:8,P00552,1.25536,NO,166,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.407,-5.55,3.143,,0.534,,B,1.04,1.03,13.995,13.995,71.59,HHO,-2.421,0.100394,0.00799912,1.25536 kka2_1:8_W91Y,kka2_1:8_91,Kka2,kka2_1:8,P00552,1.25547,NO,91,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-1.178,-2.672,1.494,,0.077,E,B,1.51,0.27,2.51,,48.48,AHH,-1.51,0.100394,0.00358653,1.25547 kka2_1:8_W91Y,kka2_1:8_91,Kka2,kka2_1:8,P00552,1.25547,NO,91,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-1.178,-2.672,1.494,,0.077,E,B,1.51,0.27,2.51,,48.48,AHH,-1.51,0.100394,0.00358653,1.25547 kka2_1:2_I254Q,kka2_1:2_254,Kka2,kka2_1:2,P00552,1.25554,NO,254,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.933,-4.193,2.26,,0.135,H,A,1.52,-0.6,2.562,,71.59,BHH,-1.668,0.295029,0.0132375,1.25554 beta-lactamase_0_R162N,beta-lactamase_0_162,TEM-1,beta-lactamase_0,P62593,1.25557,NO,162,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.016,-3.588,2.572,,0.124,S,B,1.2,-0.37,1.026,,64.69,ABH,-1.25,0.0500837,0.000561334,1.25557 kka2_1:4_A14T,kka2_1:4_14,Kka2,kka2_1:4,P00552,1.2556,NO,14,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.837,-2.286,0.449,,0.728,G,A,0.46,0.7,0.36,,71.59,HHH,-1.82567,0.168804,0.00706614,1.2556 kka2_1:2_T72K,kka2_1:2_72,Kka2,kka2_1:2,P00552,1.25569,NO,72,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.38,-2.635,0.255,,0.784,H,A,0.82,0.29,6.463,,65.53,HPP,-2.238,0.295029,0.00750756,1.25569 kka2_1:8_S251C,kka2_1:8_251,Kka2,kka2_1:8,P00552,1.25569,NO,251,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.636,-5.186,2.55,,0.712,H,A,0.27,-0.25,,,71.59,APP,-2.09367,0.100394,0.0138916,1.25569 kka2_1:8_S251C,kka2_1:8_251,Kka2,kka2_1:8,P00552,1.25569,NO,251,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.636,-5.186,2.55,,0.712,H,A,0.27,-0.25,,,71.59,APP,-2.09367,0.100394,0.0138916,1.25569 kka2_1:2_E199S,kka2_1:2_199,Kka2,kka2_1:2,P00552,1.25571,NO,199,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.234,-2.389,0.155,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.295029,0.00854122,1.25571 kka2_1:4_A108H,kka2_1:4_108,Kka2,kka2_1:4,P00552,1.25572,NO,108,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.061,-3.555,1.494,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.168804,0.00751209,1.25572 kka2_1:8_R177C,kka2_1:8_177,Kka2,kka2_1:8,P00552,1.25579,NO,177,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.282,-5.144,2.862,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.100394,0.00768224,1.25579 kka2_1:8_R177C,kka2_1:8_177,Kka2,kka2_1:8,P00552,1.25579,NO,177,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.282,-5.144,2.862,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.100394,0.00768224,1.25579 kka2_1:4_E230C,kka2_1:4_230,Kka2,kka2_1:4,P00552,1.25587,NO,230,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.672,-3.614,0.942,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.168804,0.00920051,1.25587 kka2_1:2_E3N,kka2_1:2_3,Kka2,kka2_1:2,P00552,1.25595,NO,3,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.199,-3.328,1.129,,,,,,,7.22,,92.05,HAP,-2.11567,0.295029,0.00267607,1.25595 kka2_1:2_A172N,kka2_1:2_172,Kka2,kka2_1:2,P00552,1.25596,NO,172,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.757,-3.17,1.413,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.295029,0.0079265,1.25596 kka2_1:4_H139I,kka2_1:4_139,Kka2,kka2_1:4,P00552,1.25603,NO,139,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-2.809,-3.326,0.517,,0.471,H,A,0.17,0.68,12.761,12.761,63.64,BBB,-2.22,0.168804,0.00734779,1.25603 kka2_1:8_L39G,kka2_1:8_39,Kka2,kka2_1:8,P00552,1.25605,NO,39,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.223,-2.832,1.609,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.100394,0.00493618,1.25605 kka2_1:8_L39G,kka2_1:8_39,Kka2,kka2_1:8,P00552,1.25605,NO,39,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.223,-2.832,1.609,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.100394,0.00493618,1.25605 kka2_1:4_A168C,kka2_1:4_168,Kka2,kka2_1:4,P00552,1.25606,NO,168,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.989,-5.174,3.185,,0.67,H,A,0.46,0.15,,,64.39,OHA,-2.12933,0.168804,0.00806773,1.25606 kka2_1:4_V242F,kka2_1:4_242,Kka2,kka2_1:4,P00552,1.2561,NO,242,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-2.687,-4.427,1.74,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.168804,0.0102575,1.2561 kka2_1:4_D23F,kka2_1:4_23,Kka2,kka2_1:4,P00552,1.25629,NO,23,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.459,-4.448,1.989,,0.695,E,B,0.75,-0.65,2.416,,65.53,HAH,-1.94033,0.168804,0.007195,1.25629 kka2_1:2_A166C,kka2_1:2_166,Kka2,kka2_1:2,P00552,1.25635,NO,166,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.407,-5.041,2.634,,0.534,.,B,0.46,1.03,23.175,23.175,71.59,HHO,-2.421,0.295029,0.00799912,1.25635 kka2_1:8_G10L,kka2_1:8_10,Kka2,kka2_1:8,P00552,1.25639,NO,10,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.921,-3.61,1.689,,,,,,,1.862,,71.59,HOP,-2.10733,0.100394,0.00289233,1.25639 kka2_1:8_G10L,kka2_1:8_10,Kka2,kka2_1:8,P00552,1.25639,NO,10,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.921,-3.61,1.689,,,,,,,1.862,,71.59,HOP,-2.10733,0.100394,0.00289233,1.25639 kka2_1:8_C77T,kka2_1:8_77,Kka2,kka2_1:8,P00552,1.25646,NO,77,C,T,CT,Special,Polar,5.07,5.6,0.53,149,121,119,-2,108.5,116.1,7.6,-1.477,-3.496,2.019,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.100394,0.00441216,1.25646 kka2_1:8_C77T,kka2_1:8_77,Kka2,kka2_1:8,P00552,1.25646,NO,77,C,T,CT,Special,Polar,5.07,5.6,0.53,149,121,119,-2,108.5,116.1,7.6,-1.477,-3.496,2.019,,0.229,B,b,1.5,-0.57,2.499,,63.26,OOH,-1.55667,0.100394,0.00441216,1.25646 kka2_1:8_A25L,kka2_1:8_25,Kka2,kka2_1:8,P00552,1.25667,NO,25,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.496,-3.561,1.065,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.100394,0.00595636,1.25667 kka2_1:8_A25L,kka2_1:8_25,Kka2,kka2_1:8,P00552,1.25667,NO,25,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.496,-3.561,1.065,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.100394,0.00595636,1.25667 kka2_1:8_D154N,kka2_1:8_154,Kka2,kka2_1:8,P00552,1.25667,NO,154,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.876,-2.341,1.465,,0.457,,b,0.29,1.48,0.844,,52.65,HAP,-1.52467,0.100394,0.00292633,1.25667 kka2_1:8_D154N,kka2_1:8_154,Kka2,kka2_1:8,P00552,1.25667,NO,154,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-0.876,-2.341,1.465,,0.457,,b,0.29,1.48,0.844,,52.65,HAP,-1.52467,0.100394,0.00292633,1.25667 kka2_1:8_S40H,kka2_1:8_40,Kka2,kka2_1:8,P00552,1.25669,NO,40,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.645,-3.006,0.361,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.100394,0.00693477,1.25669 kka2_1:8_S40H,kka2_1:8_40,Kka2,kka2_1:8,P00552,1.25669,NO,40,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.645,-3.006,0.361,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.100394,0.00693477,1.25669 kka2_1:4_Q252H,kka2_1:4_252,Kka2,kka2_1:4,P00552,1.2567,NO,252,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.63,-3.494,0.864,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.168804,0.0121001,1.2567 kka2_1:8_A168G,kka2_1:8_168,Kka2,kka2_1:8,P00552,1.2567,NO,168,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.989,-2.951,0.962,,0.67,H,A,0.46,0.15,11.329,11.329,64.39,OHA,-2.12933,0.100394,0.00806773,1.2567 kka2_1:8_A168G,kka2_1:8_168,Kka2,kka2_1:8,P00552,1.2567,NO,168,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.989,-2.951,0.962,,0.67,H,A,0.46,0.15,11.329,11.329,64.39,OHA,-2.12933,0.100394,0.00806773,1.2567 kka2_1:8_Q219M,kka2_1:8_219,Kka2,kka2_1:8,P00552,1.25676,NO,219,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-0.93,-4.327,3.397,,0.088,H,A,0.4,-0.85,0.897,,50,HPA,-1.05167,0.100394,0.00237913,1.25676 kka2_1:8_Q219M,kka2_1:8_219,Kka2,kka2_1:8,P00552,1.25676,NO,219,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-0.93,-4.327,3.397,,0.088,H,A,0.4,-0.85,0.897,,50,HPA,-1.05167,0.100394,0.00237913,1.25676 kka2_1:8_E199S,kka2_1:8_199,Kka2,kka2_1:8,P00552,1.25681,NO,199,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.234,-2.389,0.155,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.100394,0.00854122,1.25681 kka2_1:8_E199S,kka2_1:8_199,Kka2,kka2_1:8,P00552,1.25681,NO,199,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.234,-2.389,0.155,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.100394,0.00854122,1.25681 kka2_1:2_S114K,kka2_1:2_114,Kka2,kka2_1:2,P00552,1.25687,NO,114,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.527,-3.596,1.069,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.295029,0.00705262,1.25687 kka2_1:8_L47Q,kka2_1:8_47,Kka2,kka2_1:8,P00552,1.25697,NO,47,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.265,-2.824,1.559,,0.139,E,B,1.59,-0.86,5.086,,63.26,HHH,-1.77933,0.100394,0.00509386,1.25697 kka2_1:8_L47Q,kka2_1:8_47,Kka2,kka2_1:8,P00552,1.25697,NO,47,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.265,-2.824,1.559,,0.139,E,B,1.59,-0.86,5.086,,63.26,HHH,-1.77933,0.100394,0.00509386,1.25697 kka2_1:2_I254L,kka2_1:2_254,Kka2,kka2_1:2,P00552,1.25703,NO,254,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.933,-1.561,-0.372,,0.135,H,A,1.52,-0.6,2.562,,71.59,BHH,-1.668,0.295029,0.0132375,1.25703 beta-lactamase_0_A230C,beta-lactamase_0_230,TEM-1,beta-lactamase_0,P62593,1.2571,NO,230,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.154,-4.695,3.541,,0.01,E,B,0.46,-1.17,2.179,,50,HHA,-1.079,0.0500837,0.00516841,1.2571 kka2_1:4_D52H,kka2_1:4_52,Kka2,kka2_1:4,P00552,1.25713,NO,52,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.271,-4.302,2.031,,0.22,E,B,0.75,0.8,0.349,,71.59,PAH,-2.38367,0.168804,0.00175694,1.25713 kka2_1:4_L47C,kka2_1:4_47,Kka2,kka2_1:4,P00552,1.2572,NO,47,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.265,-4.875,3.61,,0.139,E,B,0.55,-0.86,2.369,,63.26,HHH,-1.77933,0.168804,0.00509386,1.2572 beta-lactamase_0_G90C,beta-lactamase_0_90,TEM-1,beta-lactamase_0,P62593,1.25722,NO,90,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-2.091,-5.167,3.076,,0.598,T,A,0.29,0.32,2.04,,77.62,HOB,-1.52633,0.0500837,0.00490273,1.25722 kka2_1:4_A129Q,kka2_1:4_129,Kka2,kka2_1:4,P00552,1.25754,NO,129,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.656,-3.989,2.333,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.168804,0.00726862,1.25754 kka2_1:2_F20L,kka2_1:2_20,Kka2,kka2_1:2,P00552,1.2576,NO,20,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-3.354,-3.523,0.169,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.295029,0.00701744,1.2576 kka2_1:4_L243N,kka2_1:4_243,Kka2,kka2_1:4,P00552,1.25767,NO,243,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-2.651,-3.218,0.567,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.168804,0.00884927,1.25767 beta-lactamase_0_E61Q,beta-lactamase_0_61,TEM-1,beta-lactamase_0,P62593,1.2578,NO,61,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.115,-2.702,0.587,,0.775,T,a,1.04,1.29,34.763,34.763,77.62,OAA,-1.92567,0.0500837,0.00440955,1.2578 kka2_1:2_A79S,kka2_1:2_79,Kka2,kka2_1:2,P00552,1.25784,NO,79,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.368,-2.87,0.502,,0.563,.,B,0.46,-0.43,0.475,,71.59,HHH,-1.752,0.295029,0.00664821,1.25784 beta-lactamase_0_E119M,beta-lactamase_0_119,TEM-1,beta-lactamase_0,P62593,1.25801,NO,119,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.412,-4.79,3.378,,0.358,H,A,1.04,0.51,3.396,,63.99,BAH,-1.623,0.0500837,0.00386966,1.25801 kka2_1:4_L47I,kka2_1:4_47,Kka2,kka2_1:4,P00552,1.25807,NO,47,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.265,-3.255,1.99,,0.139,E,B,0.55,-0.86,2.369,,63.26,HHH,-1.77933,0.168804,0.00509386,1.25807 WW_domain_D170R,WW_domain_170,Yap65,WW_domain,P46937,1.25811,NO,170,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.213,-3.623,2.41,,,,,,,0.399,,15.87,OAH,-1.38,0.153962,0.00123319,1.25811 kka2_1:4_Q155L,kka2_1:4_155,Kka2,kka2_1:4,P00552,1.25812,NO,155,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.606,-3.573,0.967,,0.525,T,A,0.64,1.49,1.592,,63.64,APA,-1.726,0.168804,0.00641853,1.25812 kka2_1:2_I246M,kka2_1:2_246,Kka2,kka2_1:2,P00552,1.25823,NO,246,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-2.008,-2.785,0.777,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.295029,0.0139479,1.25823 beta-lactamase_0_L196F,beta-lactamase_0_196,TEM-1,beta-lactamase_0,P62593,1.25826,NO,196,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-2.478,-4.226,1.748,,0.518,S,A,0.55,1.35,6.513,6.513,77.62,AHH,-1.839,0.0500837,0.00512144,1.25826 beta-lactamase_0_E279Y,beta-lactamase_0_279,TEM-1,beta-lactamase_0,P62593,1.25827,NO,279,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.038,,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.0500837,0.0192826,1.25827 kka2_1:2_A129L,kka2_1:2_129,Kka2,kka2_1:2,P00552,1.25837,NO,129,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.656,-3.565,1.909,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.295029,0.00726862,1.25837 kka2_1:4_D82N,kka2_1:4_82,Kka2,kka2_1:4,P00552,1.25837,NO,82,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.946,-3.098,1.152,,0.341,E,b,0.75,0.52,11.923,11.923,63.64,HAH,-1.98,0.168804,0.00637516,1.25837 kka2_1:4_E17K,kka2_1:4_17,Kka2,kka2_1:4,P00552,1.25842,NO,17,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.154,-2.831,0.677,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.168804,0.00688738,1.25842 kka2_1:8_F20M,kka2_1:8_20,Kka2,kka2_1:8,P00552,1.25843,NO,20,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-3.354,-4.754,1.4,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.100394,0.00701744,1.25843 kka2_1:8_F20M,kka2_1:8_20,Kka2,kka2_1:8,P00552,1.25843,NO,20,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-3.354,-4.754,1.4,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.100394,0.00701744,1.25843 kka2_1:4_E169T,kka2_1:4_169,Kka2,kka2_1:4,P00552,1.25846,NO,169,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.996,-2.692,0.696,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.168804,0.00730086,1.25846 beta-lactamase_0_K232A,beta-lactamase_0_232,TEM-1,beta-lactamase_0,P62593,1.25863,NO,232,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-1.012,-3.12,2.108,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.0500837,0.00313441,1.25863 kka2_1:8_R143N,kka2_1:8_143,Kka2,kka2_1:8,P00552,1.25867,NO,143,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.525,-3.927,1.402,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.100394,0.00662247,1.25867 kka2_1:8_R143N,kka2_1:8_143,Kka2,kka2_1:8,P00552,1.25867,NO,143,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.525,-3.927,1.402,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.100394,0.00662247,1.25867 kka2_1:4_A108G,kka2_1:4_108,Kka2,kka2_1:4,P00552,1.25904,NO,108,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.061,-2.917,0.856,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.168804,0.00751209,1.25904 kka2_1:8_A79N,kka2_1:8_79,Kka2,kka2_1:8,P00552,1.25913,NO,79,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.368,-3.84,1.472,,0.563,.,B,0.46,-0.43,,,71.59,HHH,-1.752,0.100394,0.00664821,1.25913 kka2_1:8_A79N,kka2_1:8_79,Kka2,kka2_1:8,P00552,1.25913,NO,79,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.368,-3.84,1.472,,0.563,.,B,0.46,-0.43,,,71.59,HHH,-1.752,0.100394,0.00664821,1.25913 kka2_1:2_E160Y,kka2_1:2_160,Kka2,kka2_1:2,P00552,1.25916,NO,160,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.683,-4.448,2.765,,0.989,G,A,1.04,2.28,3.948,,71.59,AAA,-1.36133,0.295029,0.00935762,1.25916 kka2_1:4_A137V,kka2_1:4_137,Kka2,kka2_1:4,P00552,1.25919,NO,137,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.156,-2.289,0.133,,0.029,H,A,0.46,0.34,2.227,,63.26,PHB,-2.559,0.168804,0.00515054,1.25919 kka2_1:4_M178T,kka2_1:4_178,Kka2,kka2_1:4,P00552,1.25925,NO,178,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-3.206,-3.644,0.438,,0.554,.,b,0.55,0.68,9.913,9.913,71.59,BHO,-2.154,0.168804,0.00717253,1.25925 kka2_1:8_I29T,kka2_1:8_29,Kka2,kka2_1:8,P00552,1.25926,NO,29,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.692,-2.952,1.26,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.100394,0.00619521,1.25926 kka2_1:8_I29T,kka2_1:8_29,Kka2,kka2_1:8,P00552,1.25926,NO,29,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.692,-2.952,1.26,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.100394,0.00619521,1.25926 kka2_1:1_Q4P,kka2_1:1_4,Kka2,kka2_1:1,P00552,1.2593,NO,4,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.361,-3.662,1.301,,,,,,,5.615,,71.59,APA,-1.95533,0.520039,0.00239179,1.2593 kka2_1:2_A176Q,kka2_1:2_176,Kka2,kka2_1:2,P00552,1.25936,NO,176,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.621,-3.141,1.52,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.295029,0.0083587,1.25936 kka2_1:8_H106Q,kka2_1:8_106,Kka2,kka2_1:8,P00552,1.25939,NO,106,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-3.13,-3.142,0.012,,1.065,,a,0.87,-0.95,15.956,15.956,71.59,PBH,-2.10433,0.100394,0.00730778,1.25939 kka2_1:8_H106Q,kka2_1:8_106,Kka2,kka2_1:8,P00552,1.25939,NO,106,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-3.13,-3.142,0.012,,1.065,,a,0.87,-0.95,15.956,15.956,71.59,PBH,-2.10433,0.100394,0.00730778,1.25939 beta-lactamase_0_H110D,beta-lactamase_0_110,TEM-1,beta-lactamase_0,P62593,1.25948,NO,110,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-1.706,-3.678,1.972,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.0500837,0.00441499,1.25948 kka2_1:4_E3Q,kka2_1:4_3,Kka2,kka2_1:4,P00552,1.25961,NO,3,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.199,-3.602,1.403,,,,,,,7.22,,92.05,HAP,-2.11567,0.168804,0.00267607,1.25961 kka2_1:2_G234F,kka2_1:2_234,Kka2,kka2_1:2,P00552,1.25967,NO,234,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-2.9,-4.504,1.604,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.295029,0.00984449,1.25967 gb1_A250Y,gb1_250,gb1,gb1,P06654,1.25968,NO,250,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.713,-4.028,2.315,,,,,,,3.465,,45.54,HHP,-1.74867,0.177985,0.00332003,1.25968 kka2_1:4_V242D,kka2_1:4_242,Kka2,kka2_1:4,P00552,1.25972,NO,242,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-2.687,-2.207,-0.48,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.168804,0.0102575,1.25972 kka2_1:4_A168Y,kka2_1:4_168,Kka2,kka2_1:4,P00552,1.25986,NO,168,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.989,-4.327,2.338,,0.67,H,A,0.46,0.15,,,64.39,OHA,-2.12933,0.168804,0.00806773,1.25986 kka2_1:4_A150M,kka2_1:4_150,Kka2,kka2_1:4,P00552,1.26002,NO,150,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.949,-4.623,3.674,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.168804,0.0045009,1.26002 kka2_1:8_W24F,kka2_1:8_24,Kka2,kka2_1:8,P00552,1.26005,NO,24,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-1.779,-2.325,0.546,,0.477,E,B,1.51,-0.21,2.503,,56.06,AHH,-2.24467,0.100394,0.00631564,1.26005 kka2_1:8_W24F,kka2_1:8_24,Kka2,kka2_1:8,P00552,1.26005,NO,24,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-1.779,-2.325,0.546,,0.477,E,B,1.51,-0.21,2.503,,56.06,AHH,-2.24467,0.100394,0.00631564,1.26005 kka2_1:4_H106R,kka2_1:4_106,Kka2,kka2_1:4,P00552,1.26012,NO,106,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-3.13,-2.944,-0.186,,1.065,.,a,0.17,-0.95,16.74,16.74,71.59,PBH,-2.10433,0.168804,0.00730778,1.26012 kka2_1:4_Q61D,kka2_1:4_61,Kka2,kka2_1:4,P00552,1.2602,NO,61,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.982,-3.015,0.033,,0.591,H,A,0.64,0.41,3.484,,65.53,HPA,-1.85667,0.168804,0.00612092,1.2602 kka2_1:8_G6E,kka2_1:8_6,Kka2,kka2_1:8,P00552,1.26034,NO,6,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.685,-3.379,1.694,,,,,,,,,71.59,AOH,-1.639,0.100394,0.00204693,1.26034 kka2_1:8_G6E,kka2_1:8_6,Kka2,kka2_1:8,P00552,1.26034,NO,6,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.685,-3.379,1.694,,,,,,,,,71.59,AOH,-1.639,0.100394,0.00204693,1.26034 kka2_1:4_G43S,kka2_1:4_43,Kka2,kka2_1:4,P00552,1.26051,NO,43,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.587,-2.69,1.103,,0.862,T,l,0.75,-0.67,2.247,,63.26,POB,-2.18533,0.168804,0.0071925,1.26051 kka2_1:8_H106K,kka2_1:8_106,Kka2,kka2_1:8,P00552,1.26078,NO,106,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-3.13,-3.67,0.54,,1.065,,a,0.87,-0.95,15.956,15.956,71.59,PBH,-2.10433,0.100394,0.00730778,1.26078 kka2_1:8_H106K,kka2_1:8_106,Kka2,kka2_1:8,P00552,1.26078,NO,106,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-3.13,-3.67,0.54,,1.065,,a,0.87,-0.95,15.956,15.956,71.59,PBH,-2.10433,0.100394,0.00730778,1.26078 beta-lactamase_0_K30T,beta-lactamase_0_30,TEM-1,beta-lactamase_0,P62593,1.26085,NO,30,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-2.307,-2.199,-0.108,,0.142,H,A,2.34,-0.65,1.491,,93.01,HBH,-2.32833,0.0500837,0.00448593,1.26085 kka2_1:8_A9W,kka2_1:8_9,Kka2,kka2_1:8,P00552,1.26086,NO,9,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.079,-5.293,3.214,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.100394,0.00273264,1.26086 kka2_1:8_A9W,kka2_1:8_9,Kka2,kka2_1:8,P00552,1.26086,NO,9,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.079,-5.293,3.214,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.100394,0.00273264,1.26086 kka2_1:4_I2Q,kka2_1:4_2,Kka2,kka2_1:4,P00552,1.26114,NO,2,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.787,-3.979,2.192,,,,,,,,,71.59,HHA,-1.92433,0.168804,0.00246644,1.26114 kka2_1:8_E3C,kka2_1:8_3,Kka2,kka2_1:8,P00552,1.26117,NO,3,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.199,-4.909,2.71,,,,,,,7.22,,92.05,HAP,-2.11567,0.100394,0.00267607,1.26117 kka2_1:8_E3C,kka2_1:8_3,Kka2,kka2_1:8,P00552,1.26117,NO,3,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.199,-4.909,2.71,,,,,,,7.22,,92.05,HAP,-2.11567,0.100394,0.00267607,1.26117 kka2_1:8_G234L,kka2_1:8_234,Kka2,kka2_1:8,P00552,1.26117,NO,234,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-2.9,-3.687,0.787,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.100394,0.00984449,1.26117 kka2_1:8_G234L,kka2_1:8_234,Kka2,kka2_1:8,P00552,1.26117,NO,234,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-2.9,-3.687,0.787,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.100394,0.00984449,1.26117 kka2_1:8_R239F,kka2_1:8_239,Kka2,kka2_1:8,P00552,1.26121,NO,239,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.949,-4.366,1.417,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.100394,0.00835326,1.26121 kka2_1:8_R239F,kka2_1:8_239,Kka2,kka2_1:8,P00552,1.26121,NO,239,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.949,-4.366,1.417,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.100394,0.00835326,1.26121 kka2_1:4_Q61A,kka2_1:4_61,Kka2,kka2_1:4,P00552,1.26123,NO,61,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.982,-1.987,-0.995,,0.591,H,A,0.64,0.41,3.484,,65.53,HPA,-1.85667,0.168804,0.00612092,1.26123 beta-lactamase_0_Q203K,beta-lactamase_0_203,TEM-1,beta-lactamase_0,P62593,1.26128,NO,203,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.168,-2.642,0.474,,0.47,H,A,0.64,-0.38,14.541,14.541,65.38,BPP,-1.614,0.0500837,0.00631514,1.26128 beta-lactamase_0_E26G,beta-lactamase_0_26,TEM-1,beta-lactamase_0,P62593,1.26132,NO,26,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.454,-2.639,0.185,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.0500837,0.00297948,1.26132 kka2_1:4_T130I,kka2_1:4_130,Kka2,kka2_1:4,P00552,1.26133,NO,130,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.392,-3.995,1.603,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.168804,0.00804204,1.26133 kka2_1:8_R239K,kka2_1:8_239,Kka2,kka2_1:8,P00552,1.26138,NO,239,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.949,-3.654,0.705,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.100394,0.00835326,1.26138 kka2_1:8_R239K,kka2_1:8_239,Kka2,kka2_1:8,P00552,1.26138,NO,239,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.949,-3.654,0.705,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.100394,0.00835326,1.26138 kka2_1:2_G43A,kka2_1:2_43,Kka2,kka2_1:2,P00552,1.26149,NO,43,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.587,-2.77,1.183,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.295029,0.0071925,1.26149 kka2_1:8_L103A,kka2_1:8_103,Kka2,kka2_1:8,P00552,1.26149,NO,103,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-2.362,-1.403,-0.959,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.100394,0.00574792,1.26149 kka2_1:8_L103A,kka2_1:8_103,Kka2,kka2_1:8,P00552,1.26149,NO,103,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-2.362,-1.403,-0.959,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.100394,0.00574792,1.26149 kka2_1:4_A172Y,kka2_1:4_172,Kka2,kka2_1:4,P00552,1.26173,NO,172,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.757,-4.449,2.692,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.168804,0.0079265,1.26173 WW_domain_D170P,WW_domain_170,Yap65,WW_domain,P46937,1.26185,NO,170,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.213,-3.495,2.282,,,,,,,0.399,,15.87,OAH,-1.38,0.153962,0.00123319,1.26185 kka2_1:2_L158W,kka2_1:2_158,Kka2,kka2_1:2,P00552,1.26195,NO,158,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.947,-4.75,2.803,,0.095,,B,1.59,0.77,7.588,,63.64,AHA,-1.25333,0.295029,0.00529068,1.26195 kka2_1:8_I2T,kka2_1:8_2,Kka2,kka2_1:8,P00552,1.26197,NO,2,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.787,-2.02,0.233,,,,,,,,,71.59,HHA,-1.92433,0.100394,0.00246644,1.26197 kka2_1:8_I2T,kka2_1:8_2,Kka2,kka2_1:8,P00552,1.26197,NO,2,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.787,-2.02,0.233,,,,,,,,,71.59,HHA,-1.92433,0.100394,0.00246644,1.26197 beta-lactamase_0_R239M,beta-lactamase_0_239,TEM-1,beta-lactamase_0,P62593,1.26202,NO,239,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.0500837,0.00213852,1.26202 kka2_1:2_D180R,kka2_1:2_180,Kka2,kka2_1:2,P00552,1.26203,NO,180,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.416,-2.973,0.557,,1.03,S,a,0.75,1.5,1.27,,71.59,OAO,-2.02933,0.295029,0.00756412,1.26203 kka2_1:2_Q42S,kka2_1:2_42,Kka2,kka2_1:2,P00552,1.2621,NO,42,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.907,-2.69,-0.217,,1.044,T,B,0.64,-0.8,2.792,,71.59,HPO,-2.12433,0.295029,0.00679212,1.2621 kka2_1:4_L19V,kka2_1:4_19,Kka2,kka2_1:4,P00552,1.26211,NO,19,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.254,-2.596,1.342,,0.08,T,A,1.59,-0.26,2.645,,65.53,BHH,-2.221,0.168804,0.00620703,1.26211 kka2_1:2_D23T,kka2_1:2_23,Kka2,kka2_1:2,P00552,1.26222,NO,23,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.459,-3.106,0.647,,0.695,E,B,0.75,-0.65,18.207,18.207,65.53,HAH,-1.94033,0.295029,0.007195,1.26222 kka2_1:4_A13V,kka2_1:4_13,Kka2,kka2_1:4,P00552,1.26232,NO,13,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.248,-2.845,0.597,,0.689,G,A,0.46,0.99,,,92.05,OHH,-1.646,0.168804,0.00784241,1.26232 kka2_1:4_A41H,kka2_1:4_41,Kka2,kka2_1:4,P00552,1.26239,NO,41,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.879,-3.045,1.166,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.168804,0.00543332,1.26239 kka2_1:2_V242Q,kka2_1:2_242,Kka2,kka2_1:2,P00552,1.26248,NO,242,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-2.687,-2.985,0.298,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.295029,0.0102575,1.26248 kka2_1:8_Q155M,kka2_1:8_155,Kka2,kka2_1:8,P00552,1.26253,NO,155,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.606,-4.733,2.127,,0.525,T,A,0.64,1.49,,,63.64,APA,-1.726,0.100394,0.00641853,1.26253 kka2_1:8_Q155M,kka2_1:8_155,Kka2,kka2_1:8,P00552,1.26253,NO,155,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.606,-4.733,2.127,,0.525,T,A,0.64,1.49,,,63.64,APA,-1.726,0.100394,0.00641853,1.26253 kka2_1:8_G95K,kka2_1:8_95,Kka2,kka2_1:8,P00552,1.26263,NO,95,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-2.403,-3.514,1.111,,0.126,E,B,0.75,-0.74,7.774,,71.59,HOA,-2.198,0.100394,0.00743616,1.26263 kka2_1:8_G95K,kka2_1:8_95,Kka2,kka2_1:8,P00552,1.26263,NO,95,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-2.403,-3.514,1.111,,0.126,E,B,0.75,-0.74,7.774,,71.59,HOA,-2.198,0.100394,0.00743616,1.26263 kka2_1:8_R177Y,kka2_1:8_177,Kka2,kka2_1:8,P00552,1.26282,NO,177,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.282,-4.382,2.1,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.100394,0.00768224,1.26282 kka2_1:8_R177Y,kka2_1:8_177,Kka2,kka2_1:8,P00552,1.26282,NO,177,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.282,-4.382,2.1,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.100394,0.00768224,1.26282 kka2_1:4_F256W,kka2_1:4_256,Kka2,kka2_1:4,P00552,1.2629,NO,256,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.49,-2.846,1.356,,,H,A,0.58,-0.78,1.653,,53.03,HHH,-1.423,0.168804,0.0132841,1.2629 kka2_1:2_D238S,kka2_1:2_238,Kka2,kka2_1:2,P00552,1.26294,NO,238,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.83,-2.933,0.103,,0.604,H,A,0.75,-0.33,22.789,22.789,92.05,HAB,-2.633,0.295029,0.0113863,1.26294 kka2_1:4_R202H,kka2_1:4_202,Kka2,kka2_1:4,P00552,1.26311,NO,202,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.761,-2.934,1.173,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.168804,0.00696498,1.26311 beta-lactamase_0_L120D,beta-lactamase_0_120,TEM-1,beta-lactamase_0,P62593,1.26316,NO,120,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.044,-4.076,3.032,,,H,A,0.55,-1.13,1.2,,64.69,AHO,-1.13633,0.0500837,0.00143563,1.26316 kka2_1:2_Q26R,kka2_1:2_26,Kka2,kka2_1:2,P00552,1.26317,NO,26,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.18,-1.791,-0.389,,0.448,E,B,0.4,0.44,5.022,,92.05,HPP,-2.11167,0.295029,0.00708962,1.26317 kka2_1:8_L243K,kka2_1:8_243,Kka2,kka2_1:8,P00552,1.26317,NO,243,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-2.651,-3.021,0.37,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.100394,0.00884927,1.26317 kka2_1:8_L243K,kka2_1:8_243,Kka2,kka2_1:8,P00552,1.26317,NO,243,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-2.651,-3.021,0.37,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.100394,0.00884927,1.26317 kka2_1:4_Q4P,kka2_1:4_4,Kka2,kka2_1:4,P00552,1.26321,NO,4,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.361,-3.662,1.301,,,,,,,2.026,,71.59,APA,-1.95533,0.168804,0.00239179,1.26321 kka2_1:4_E149T,kka2_1:4_149,Kka2,kka2_1:4,P00552,1.26322,NO,149,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.994,-3.656,1.662,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.168804,0.00803343,1.26322 kka2_1:2_D180E,kka2_1:2_180,Kka2,kka2_1:2,P00552,1.26333,NO,180,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.416,-2.535,0.119,,1.03,S,a,0.75,1.5,1.27,,71.59,OAO,-2.02933,0.295029,0.00756412,1.26333 kka2_1:8_L165H,kka2_1:8_165,Kka2,kka2_1:8,P00552,1.26335,NO,165,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-2.453,-4.763,2.31,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.100394,0.00801161,1.26335 kka2_1:8_L165H,kka2_1:8_165,Kka2,kka2_1:8,P00552,1.26335,NO,165,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-2.453,-4.763,2.31,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.100394,0.00801161,1.26335 kka2_1:4_G234S,kka2_1:4_234,Kka2,kka2_1:4,P00552,1.26339,NO,234,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-2.9,-2.468,-0.432,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.168804,0.00984449,1.26339 kka2_1:8_D23A,kka2_1:8_23,Kka2,kka2_1:8,P00552,1.26345,NO,23,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.459,-2.468,0.009,,0.695,E,B,0.75,-0.65,,,65.53,HAH,-1.94033,0.100394,0.007195,1.26345 kka2_1:8_D23A,kka2_1:8_23,Kka2,kka2_1:8,P00552,1.26345,NO,23,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.459,-2.468,0.009,,0.695,E,B,0.75,-0.65,,,65.53,HAH,-1.94033,0.100394,0.007195,1.26345 kka2_1:4_P12V,kka2_1:4_12,Kka2,kka2_1:4,P00552,1.26354,NO,12,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.853,-3.479,2.626,,,,B,0.52,1.25,0.843,,48.11,POH,-1.80767,0.168804,0.00500011,1.26354 kka2_1:2_A108H,kka2_1:2_108,Kka2,kka2_1:2,P00552,1.2636,NO,108,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.061,-3.555,1.494,,0.243,.,B,0.46,-1.34,2.462,,71.59,HHO,-1.57033,0.295029,0.00751209,1.2636 kka2_1:4_E199L,kka2_1:4_199,Kka2,kka2_1:4,P00552,1.26371,NO,199,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.234,-3.058,0.824,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.168804,0.00854122,1.26371 beta-lactamase_0_I280F,beta-lactamase_0_280,TEM-1,beta-lactamase_0,P62593,1.26377,NO,280,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.708,,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.0500837,0.0530888,1.26377 beta-lactamase_0_I285D,beta-lactamase_0_285,TEM-1,beta-lactamase_0,P62593,1.26379,NO,285,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.0500837,0.101555,1.26379 kka2_1:4_G234F,kka2_1:4_234,Kka2,kka2_1:4,P00552,1.26381,NO,234,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-2.9,-4.504,1.604,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.168804,0.00984449,1.26381 kka2_1:8_V83F,kka2_1:8_83,Kka2,kka2_1:8,P00552,1.26384,NO,83,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-2.567,-2.568,0.001,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.100394,0.00650486,1.26384 kka2_1:8_V83F,kka2_1:8_83,Kka2,kka2_1:8,P00552,1.26384,NO,83,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-2.567,-2.568,0.001,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.100394,0.00650486,1.26384 kka2_1:4_G10T,kka2_1:4_10,Kka2,kka2_1:4,P00552,1.26393,NO,10,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.921,-3.48,1.559,,,,,,,1.862,,71.59,HOP,-2.10733,0.168804,0.00289233,1.26393 kka2_1:4_S11I,kka2_1:4_11,Kka2,kka2_1:4,P00552,1.26397,NO,11,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.322,-2.514,0.192,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.168804,0.00381691,1.26397 kka2_1:4_A172C,kka2_1:4_172,Kka2,kka2_1:4,P00552,1.26405,NO,172,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.757,-5.069,3.312,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.168804,0.0079265,1.26405 kka2_1:2_S68C,kka2_1:2_68,Kka2,kka2_1:2,P00552,1.26409,NO,68,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.623,-3.588,0.965,,0.48,H,A,0.27,-0.1,2.655,,71.59,HPH,-1.40767,0.295029,0.00608265,1.26409 kka2_1:2_E199Y,kka2_1:2_199,Kka2,kka2_1:2,P00552,1.26412,NO,199,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.234,-4.316,2.082,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.295029,0.00854122,1.26412 kka2_1:4_A108Q,kka2_1:4_108,Kka2,kka2_1:4,P00552,1.26416,NO,108,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.061,-3.285,1.224,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.168804,0.00751209,1.26416 kka2_1:2_A168H,kka2_1:2_168,Kka2,kka2_1:2,P00552,1.26418,NO,168,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.989,-3.256,1.267,,0.67,H,A,0.46,0.15,25.546,25.546,64.39,OHA,-2.12933,0.295029,0.00806773,1.26418 kka2_1:8_E3Y,kka2_1:8_3,Kka2,kka2_1:8,P00552,1.26419,NO,3,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.199,-2.458,0.259,,,,,,,7.22,,92.05,HAP,-2.11567,0.100394,0.00267607,1.26419 kka2_1:8_E3Y,kka2_1:8_3,Kka2,kka2_1:8,P00552,1.26419,NO,3,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.199,-2.458,0.259,,,,,,,7.22,,92.05,HAP,-2.11567,0.100394,0.00267607,1.26419 kka2_1:4_A35G,kka2_1:4_35,Kka2,kka2_1:4,P00552,1.26424,NO,35,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.127,-2.532,0.405,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.168804,0.00630016,1.26424 kka2_1:8_R177H,kka2_1:8_177,Kka2,kka2_1:8,P00552,1.26426,NO,177,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.282,-3.561,1.279,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.100394,0.00768224,1.26426 kka2_1:8_R177H,kka2_1:8_177,Kka2,kka2_1:8,P00552,1.26426,NO,177,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.282,-3.561,1.279,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.100394,0.00768224,1.26426 kka2_1:4_W91F,kka2_1:4_91,Kka2,kka2_1:4,P00552,1.26428,NO,91,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,-1.178,-2.297,1.119,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.168804,0.00358653,1.26428 kka2_1:4_D52C,kka2_1:4_52,Kka2,kka2_1:4,P00552,1.26431,NO,52,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.271,-5.339,3.068,,0.22,E,B,0.75,0.8,0.349,,71.59,PAH,-2.38367,0.168804,0.00175694,1.26431 kka2_1:2_V46S,kka2_1:2_46,Kka2,kka2_1:2,P00552,1.26432,NO,46,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-2.62,-2.564,-0.056,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.295029,0.00631301,1.26432 kka2_1:8_A13D,kka2_1:8_13,Kka2,kka2_1:8,P00552,1.26432,NO,13,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.248,-2.729,0.481,,0.689,G,A,1.04,0.99,14.966,14.966,92.05,OHH,-1.646,0.100394,0.00784241,1.26432 kka2_1:8_A13D,kka2_1:8_13,Kka2,kka2_1:8,P00552,1.26432,NO,13,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.248,-2.729,0.481,,0.689,G,A,1.04,0.99,14.966,14.966,92.05,OHH,-1.646,0.100394,0.00784241,1.26432 kka2_1:4_T146I,kka2_1:4_146,Kka2,kka2_1:4,P00552,1.26448,NO,146,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.978,-3.15,0.172,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.168804,0.00606474,1.26448 kka2_1:8_E3D,kka2_1:8_3,Kka2,kka2_1:8,P00552,1.26454,NO,3,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.199,-1.902,-0.297,,,,,,,7.22,,92.05,HAP,-2.11567,0.100394,0.00267607,1.26454 kka2_1:8_E3D,kka2_1:8_3,Kka2,kka2_1:8,P00552,1.26454,NO,3,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.199,-1.902,-0.297,,,,,,,7.22,,92.05,HAP,-2.11567,0.100394,0.00267607,1.26454 kka2_1:8_E3R,kka2_1:8_3,Kka2,kka2_1:8,P00552,1.26458,NO,3,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.199,-3.722,1.523,,,,,,,7.22,,92.05,HAP,-2.11567,0.100394,0.00267607,1.26458 kka2_1:8_E3R,kka2_1:8_3,Kka2,kka2_1:8,P00552,1.26458,NO,3,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.199,-3.722,1.523,,,,,,,7.22,,92.05,HAP,-2.11567,0.100394,0.00267607,1.26458 kka2_1:8_L7H,kka2_1:8_7,Kka2,kka2_1:8,P00552,1.26461,NO,7,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.926,-2.581,0.655,,,,,,,,,71.59,OHB,-2.12333,0.100394,0.00269456,1.26461 kka2_1:8_L7H,kka2_1:8_7,Kka2,kka2_1:8,P00552,1.26461,NO,7,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.926,-2.581,0.655,,,,,,,,,71.59,OHB,-2.12333,0.100394,0.00269456,1.26461 kka2_1:2_V153I,kka2_1:2_153,Kka2,kka2_1:2,P00552,1.26477,NO,153,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.092,-1.693,0.601,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.295029,0.00501119,1.26477 kka2_1:2_A13T,kka2_1:2_13,Kka2,kka2_1:2,P00552,1.2648,NO,13,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.248,-2.994,0.746,,0.689,G,A,0.46,0.99,,,92.05,OHH,-1.646,0.295029,0.00784241,1.2648 kka2_1:8_E3K,kka2_1:8_3,Kka2,kka2_1:8,P00552,1.26484,NO,3,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.199,-3.312,1.113,,,,,,,7.22,,92.05,HAP,-2.11567,0.100394,0.00267607,1.26484 kka2_1:8_E3K,kka2_1:8_3,Kka2,kka2_1:8,P00552,1.26484,NO,3,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.199,-3.312,1.113,,,,,,,7.22,,92.05,HAP,-2.11567,0.100394,0.00267607,1.26484 kka2_1:8_G43Y,kka2_1:8_43,Kka2,kka2_1:8,P00552,1.26484,NO,43,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.587,-3.332,1.745,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.100394,0.0071925,1.26484 kka2_1:8_G43Y,kka2_1:8_43,Kka2,kka2_1:8,P00552,1.26484,NO,43,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.587,-3.332,1.745,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.100394,0.0071925,1.26484 kka2_1:4_R239E,kka2_1:4_239,Kka2,kka2_1:4,P00552,1.26501,NO,239,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.949,-2.985,0.036,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.168804,0.00835326,1.26501 kka2_1:4_E17H,kka2_1:4_17,Kka2,kka2_1:4,P00552,1.26512,NO,17,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.154,-3.247,1.093,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.168804,0.00688738,1.26512 kka2_1:4_R173N,kka2_1:4_173,Kka2,kka2_1:4,P00552,1.26516,NO,173,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.407,-3.101,0.694,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.168804,0.00784999,1.26516 kka2_1:4_D52E,kka2_1:4_52,Kka2,kka2_1:4,P00552,1.26518,NO,52,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.271,-0.829,-1.442,,0.22,E,B,0.75,0.8,0.349,,71.59,PAH,-2.38367,0.168804,0.00175694,1.26518 kka2_1:8_D52V,kka2_1:8_52,Kka2,kka2_1:8,P00552,1.26518,NO,52,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.271,-3.601,1.33,,0.22,E,B,0.75,0.8,5.447,,71.59,PAH,-2.38367,0.100394,0.00175694,1.26518 kka2_1:8_D52V,kka2_1:8_52,Kka2,kka2_1:8,P00552,1.26518,NO,52,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.271,-3.601,1.33,,0.22,E,B,0.75,0.8,5.447,,71.59,PAH,-2.38367,0.100394,0.00175694,1.26518 kka2_1:4_L7H,kka2_1:4_7,Kka2,kka2_1:4,P00552,1.26542,NO,7,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.926,-2.581,0.655,,,,,,,3.012,,71.59,OHB,-2.12333,0.168804,0.00269456,1.26542 kka2_1:2_G6R,kka2_1:2_6,Kka2,kka2_1:2,P00552,1.26556,NO,6,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.685,-3.575,1.89,,,,,,,,,71.59,AOH,-1.639,0.295029,0.00204693,1.26556 kka2_1:4_D156S,kka2_1:4_156,Kka2,kka2_1:4,P00552,1.26563,NO,156,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.696,-2.049,0.353,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.168804,0.00926998,1.26563 beta-lactamase_0_I258Y,beta-lactamase_0_258,TEM-1,beta-lactamase_0,P62593,1.26564,NO,258,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.0500837,0.007931,1.26564 beta-lactamase_0_N130E,beta-lactamase_0_130,TEM-1,beta-lactamase_0,P62593,1.26565,NO,130,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-0.798,-3.215,2.417,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.0500837,0.000683376,1.26565 kka2_1:8_D5F,kka2_1:8_5,Kka2,kka2_1:8,P00552,1.26567,NO,5,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.306,-4.103,2.797,,,,,,,1.147,,71.59,PAO,-1.784,0.100394,0.00222864,1.26567 kka2_1:8_D5F,kka2_1:8_5,Kka2,kka2_1:8,P00552,1.26567,NO,5,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.306,-4.103,2.797,,,,,,,1.147,,71.59,PAO,-1.784,0.100394,0.00222864,1.26567 kka2_1:4_G10E,kka2_1:4_10,Kka2,kka2_1:4,P00552,1.26585,NO,10,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.921,-2.456,0.535,,,,,,,1.862,,71.59,HOP,-2.10733,0.168804,0.00289233,1.26585 kka2_1:8_K175G,kka2_1:8_175,Kka2,kka2_1:8,P00552,1.26599,NO,175,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-2.897,-3.762,0.865,,0.579,H,A,2.34,0.51,15.316,15.316,71.59,HBH,-1.82333,0.100394,0.00693093,1.26599 kka2_1:8_K175G,kka2_1:8_175,Kka2,kka2_1:8,P00552,1.26599,NO,175,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-2.897,-3.762,0.865,,0.579,H,A,2.34,0.51,15.316,15.316,71.59,HBH,-1.82333,0.100394,0.00693093,1.26599 beta-lactamase_0_S241Y,beta-lactamase_0_241,TEM-1,beta-lactamase_0,P62593,1.266,NO,241,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.433,,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.0500837,0.00452736,1.266 kka2_1:2_A79G,kka2_1:2_79,Kka2,kka2_1:2,P00552,1.26605,NO,79,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.368,-2.844,0.476,,0.563,.,B,0.46,-0.43,0.475,,71.59,HHH,-1.752,0.295029,0.00664821,1.26605 kka2_1:4_I254Q,kka2_1:4_254,Kka2,kka2_1:4,P00552,1.26605,NO,254,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.933,-4.193,2.26,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.168804,0.0132375,1.26605 kka2_1:8_S11T,kka2_1:8_11,Kka2,kka2_1:8,P00552,1.26609,NO,11,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.322,-3.33,1.008,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.100394,0.00381691,1.26609 kka2_1:8_S11T,kka2_1:8_11,Kka2,kka2_1:8,P00552,1.26609,NO,11,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.322,-3.33,1.008,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.100394,0.00381691,1.26609 kka2_1:4_D33H,kka2_1:4_33,Kka2,kka2_1:4,P00552,1.26611,NO,33,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.186,-4.719,2.533,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.168804,0.00633568,1.26611 kka2_1:4_I2L,kka2_1:4_2,Kka2,kka2_1:4,P00552,1.26616,NO,2,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.787,-2.519,0.732,,,,,,,,,71.59,HHA,-1.92433,0.168804,0.00246644,1.26616 beta-lactamase_0_F58C,beta-lactamase_0_58,TEM-1,beta-lactamase_0,P62593,1.2662,NO,58,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-2.914,-5.093,2.179,,0.266,E,B,0.58,-0.07,24.637,24.637,77.62,PHB,-2.059,0.0500837,0.00523369,1.2662 kka2_1:8_A248P,kka2_1:8_248,Kka2,kka2_1:8,P00552,1.26621,NO,248,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.124,-3.022,0.898,,0.825,S,b,1.04,0.46,11.329,11.329,92.05,HHO,-2.15,0.100394,0.0125484,1.26621 kka2_1:8_A248P,kka2_1:8_248,Kka2,kka2_1:8,P00552,1.26621,NO,248,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.124,-3.022,0.898,,0.825,S,b,1.04,0.46,11.329,11.329,92.05,HHO,-2.15,0.100394,0.0125484,1.26621 kka2_1:4_D52S,kka2_1:4_52,Kka2,kka2_1:4,P00552,1.26633,NO,52,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.271,-3.212,0.941,,0.22,E,B,0.75,0.8,0.349,,71.59,PAH,-2.38367,0.168804,0.00175694,1.26633 kka2_1:8_D238C,kka2_1:8_238,Kka2,kka2_1:8,P00552,1.26642,NO,238,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.83,-5.149,2.319,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.100394,0.0113863,1.26642 kka2_1:8_D238C,kka2_1:8_238,Kka2,kka2_1:8,P00552,1.26642,NO,238,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.83,-5.149,2.319,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.100394,0.0113863,1.26642 kka2_1:2_A191C,kka2_1:2_191,Kka2,kka2_1:2,P00552,1.2665,NO,191,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.831,-4.548,3.717,,,.,b,0.46,-0.94,2.046,,50,AHO,-0.868667,0.295029,0.00338807,1.2665 kka2_1:8_V198Q,kka2_1:8_198,Kka2,kka2_1:8,P00552,1.2665,NO,198,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.719,-4.058,2.339,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.100394,0.00835002,1.2665 kka2_1:8_V198Q,kka2_1:8_198,Kka2,kka2_1:8,P00552,1.2665,NO,198,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.719,-4.058,2.339,,0.05,E,B,0.44,-0.95,1.629,,56.06,HHA,-1.88667,0.100394,0.00835002,1.2665 kka2_1:4_H8A,kka2_1:4_8,Kka2,kka2_1:4,P00552,1.26659,NO,8,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-2.759,-1.998,-0.761,,,,,,,,,71.59,HBH,-2.25467,0.168804,0.00256422,1.26659 kka2_1:2_V80I,kka2_1:2_80,Kka2,kka2_1:2,P00552,1.26679,NO,80,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.144,-1.887,0.743,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.295029,0.00488211,1.26679 kka2_1:8_A176H,kka2_1:8_176,Kka2,kka2_1:8,P00552,1.26684,NO,176,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.621,-4.691,3.07,,0.806,H,A,0.46,-0.03,18.904,18.904,65.53,BHB,-2.26667,0.100394,0.0083587,1.26684 kka2_1:8_A176H,kka2_1:8_176,Kka2,kka2_1:8,P00552,1.26684,NO,176,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.621,-4.691,3.07,,0.806,H,A,0.46,-0.03,18.904,18.904,65.53,BHB,-2.26667,0.100394,0.0083587,1.26684 kka2_1:8_S251V,kka2_1:8_251,Kka2,kka2_1:8,P00552,1.26684,NO,251,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.636,-3.716,1.08,,0.712,H,A,0.27,-0.25,,,71.59,APP,-2.09367,0.100394,0.0138916,1.26684 kka2_1:8_S251V,kka2_1:8_251,Kka2,kka2_1:8,P00552,1.26684,NO,251,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.636,-3.716,1.08,,0.712,H,A,0.27,-0.25,,,71.59,APP,-2.09367,0.100394,0.0138916,1.26684 kka2_1:8_V75S,kka2_1:8_75,Kka2,kka2_1:8,P00552,1.26688,NO,75,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-2.06,-3.699,1.639,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.100394,0.00693733,1.26688 kka2_1:8_V75S,kka2_1:8_75,Kka2,kka2_1:8,P00552,1.26688,NO,75,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-2.06,-3.699,1.639,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.100394,0.00693733,1.26688 kka2_1:8_P249K,kka2_1:8_249,Kka2,kka2_1:8,P00552,1.26696,NO,249,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.867,-3.802,1.935,,0.406,.,B,0.52,-0.01,1.699,,92.05,HOA,-1.66867,0.100394,0.011045,1.26696 kka2_1:8_P249K,kka2_1:8_249,Kka2,kka2_1:8,P00552,1.26696,NO,249,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.867,-3.802,1.935,,0.406,.,B,0.52,-0.01,1.699,,92.05,HOA,-1.66867,0.100394,0.011045,1.26696 beta-lactamase_0_Q88M,beta-lactamase_0_88,TEM-1,beta-lactamase_0,P62593,1.26698,NO,88,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.086,-3.418,1.332,,0.807,,B,0.64,2.03,0.4,,77.62,APH,-1.53433,0.0500837,0.00504167,1.26698 kka2_1:4_M178L,kka2_1:4_178,Kka2,kka2_1:4,P00552,1.26709,NO,178,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-3.206,-2.71,-0.496,,0.554,.,b,0.55,0.68,9.913,9.913,71.59,BHO,-2.154,0.168804,0.00717253,1.26709 kka2_1:2_D52S,kka2_1:2_52,Kka2,kka2_1:2,P00552,1.26713,NO,52,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.271,-3.212,0.941,,0.22,E,B,0.75,0.8,1.123,,71.59,PAH,-2.38367,0.295029,0.00175694,1.26713 kka2_1:2_G95K,kka2_1:2_95,Kka2,kka2_1:2,P00552,1.26713,NO,95,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-2.403,-3.514,1.111,,0.126,E,B,0.29,-0.74,0.359,,71.59,HOA,-2.198,0.295029,0.00743616,1.26713 kka2_1:8_D52I,kka2_1:8_52,Kka2,kka2_1:8,P00552,1.26714,NO,52,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.271,-4.062,1.791,,0.22,E,B,0.75,0.8,5.447,,71.59,PAH,-2.38367,0.100394,0.00175694,1.26714 kka2_1:8_D52I,kka2_1:8_52,Kka2,kka2_1:8,P00552,1.26714,NO,52,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.271,-4.062,1.791,,0.22,E,B,0.75,0.8,5.447,,71.59,PAH,-2.38367,0.100394,0.00175694,1.26714 kka2_1:2_A166D,kka2_1:2_166,Kka2,kka2_1:2,P00552,1.26728,NO,166,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.407,-2.968,0.561,,0.534,.,B,0.46,1.03,23.175,23.175,71.59,HHO,-2.421,0.295029,0.00799912,1.26728 kka2_1:2_L47R,kka2_1:2_47,Kka2,kka2_1:2,P00552,1.26729,NO,47,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.265,-2.763,1.498,,0.139,E,B,0.55,-0.86,2.369,,63.26,HHH,-1.77933,0.295029,0.00509386,1.26729 kka2_1:4_R253M,kka2_1:4_253,Kka2,kka2_1:4,P00552,1.2673,NO,253,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.356,-4.619,3.263,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.168804,0.0144195,1.2673 kka2_1:8_A137R,kka2_1:8_137,Kka2,kka2_1:8,P00552,1.26737,NO,137,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.156,-3.088,0.932,,0.029,H,A,1.04,0.34,2.886,,63.26,PHB,-2.559,0.100394,0.00515054,1.26737 kka2_1:8_A137R,kka2_1:8_137,Kka2,kka2_1:8,P00552,1.26737,NO,137,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.156,-3.088,0.932,,0.029,H,A,1.04,0.34,2.886,,63.26,PHB,-2.559,0.100394,0.00515054,1.26737 kka2_1:8_Q155D,kka2_1:8_155,Kka2,kka2_1:8,P00552,1.26745,NO,155,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.606,-2.377,-0.229,,0.525,T,A,0.64,1.49,,,63.64,APA,-1.726,0.100394,0.00641853,1.26745 kka2_1:8_Q155D,kka2_1:8_155,Kka2,kka2_1:8,P00552,1.26745,NO,155,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.606,-2.377,-0.229,,0.525,T,A,0.64,1.49,,,63.64,APA,-1.726,0.100394,0.00641853,1.26745 kka2_1:4_A176C,kka2_1:4_176,Kka2,kka2_1:4,P00552,1.26746,NO,176,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.621,-4.973,3.352,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.168804,0.0083587,1.26746 beta-lactamase_0_G236M,beta-lactamase_0_236,TEM-1,beta-lactamase_0,P62593,1.26754,NO,236,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.784,-4.869,4.085,,0.241,,b,0.29,-0.59,3.506,,64.69,HOO,-1.025,0.0500837,0.00162372,1.26754 kka2_1:8_A41H,kka2_1:8_41,Kka2,kka2_1:8,P00552,1.26767,NO,41,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.879,-3.045,1.166,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.100394,0.00543332,1.26767 kka2_1:8_A41H,kka2_1:8_41,Kka2,kka2_1:8,P00552,1.26767,NO,41,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.879,-3.045,1.166,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.100394,0.00543332,1.26767 kka2_1:2_H162N,kka2_1:2_162,Kka2,kka2_1:2,P00552,1.26797,NO,162,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-2.319,-2.321,0.002,,0.071,G,A,0.17,1.01,3.187,,64.39,ABP,-2.02067,0.295029,0.00616145,1.26797 kka2_1:8_A247W,kka2_1:8_247,Kka2,kka2_1:8,P00552,1.268,NO,247,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.459,-5.465,3.006,,1.01,S,A,0.46,0.65,18.904,18.904,92.05,HHH,-2.197,0.100394,0.0102428,1.268 kka2_1:8_A247W,kka2_1:8_247,Kka2,kka2_1:8,P00552,1.268,NO,247,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.459,-5.465,3.006,,1.01,S,A,0.46,0.65,18.904,18.904,92.05,HHH,-2.197,0.100394,0.0102428,1.268 kka2_1:2_A248T,kka2_1:2_248,Kka2,kka2_1:2,P00552,1.26803,NO,248,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.124,-3.092,0.968,,0.825,S,b,0.46,0.46,,,92.05,HHO,-2.15,0.295029,0.0125484,1.26803 kka2_1:4_F256Y,kka2_1:4_256,Kka2,kka2_1:4,P00552,1.26806,NO,256,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.49,-1.474,-0.016,,,H,A,0.58,-0.78,1.653,,53.03,HHH,-1.423,0.168804,0.0132841,1.26806 kka2_1:2_A25D,kka2_1:2_25,Kka2,kka2_1:2,P00552,1.26808,NO,25,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.496,-2.743,0.247,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.295029,0.00595636,1.26808 kka2_1:2_R239Q,kka2_1:2_239,Kka2,kka2_1:2,P00552,1.26825,NO,239,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.949,-4.068,1.119,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.295029,0.00835326,1.26825 kka2_1:2_A35L,kka2_1:2_35,Kka2,kka2_1:2,P00552,1.26826,NO,35,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.127,-3.045,0.918,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.295029,0.00630016,1.26826 kka2_1:2_L39G,kka2_1:2_39,Kka2,kka2_1:2,P00552,1.26835,NO,39,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.223,-2.832,1.609,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.295029,0.00493618,1.26835 beta-lactamase_0_L188N,beta-lactamase_0_188,TEM-1,beta-lactamase_0,P62593,1.26836,NO,188,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.166,-4.122,2.956,,,H,A,0.55,-0.3,2.739,,60.14,PHB,-1.47033,0.0500837,0.00295687,1.26836 kka2_1:4_R18S,kka2_1:4_18,Kka2,kka2_1:4,P00552,1.26837,NO,18,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.055,-2.892,0.837,,0.474,T,A,1.2,0.54,8.405,8.405,71.59,ABH,-1.821,0.168804,0.00724065,1.26837 kka2_1:8_G21N,kka2_1:8_21,Kka2,kka2_1:8,P00552,1.26848,NO,21,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.368,-3.58,2.212,,0.586,T,l,0.29,-0.75,4.889,,71.59,HOH,-2.10167,0.100394,0.00709648,1.26848 kka2_1:8_G21N,kka2_1:8_21,Kka2,kka2_1:8,P00552,1.26848,NO,21,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.368,-3.58,2.212,,0.586,T,l,0.29,-0.75,4.889,,71.59,HOH,-2.10167,0.100394,0.00709648,1.26848 kka2_1:4_A25M,kka2_1:4_25,Kka2,kka2_1:4,P00552,1.26855,NO,25,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.496,-3.529,1.033,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.168804,0.00595636,1.26855 kka2_1:8_Q42I,kka2_1:8_42,Kka2,kka2_1:8,P00552,1.26873,NO,42,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.907,-4.147,1.24,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.100394,0.00679212,1.26873 kka2_1:8_Q42I,kka2_1:8_42,Kka2,kka2_1:8,P00552,1.26873,NO,42,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.907,-4.147,1.24,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.100394,0.00679212,1.26873 beta-lactamase_0_R273M,beta-lactamase_0_273,TEM-1,beta-lactamase_0,P62593,1.26891,NO,273,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.314,-4.698,2.384,,0.564,H,A,1.2,1.57,20.248,20.248,73.78,ABP,-1.841,0.0500837,0.0077952,1.26891 beta-lactamase_0_I140L,beta-lactamase_0_140,TEM-1,beta-lactamase_0,P62593,1.26896,NO,140,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.733,-1.622,-0.111,,0.128,H,A,0.48,0.41,4.714,,73.08,PHO,-1.48733,0.0500837,0.00597777,1.26896 kka2_1:2_G181R,kka2_1:2_181,Kka2,kka2_1:2,P00552,1.26896,NO,181,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-2.698,-2.623,-0.075,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.295029,0.00728319,1.26896 kka2_1:2_E199R,kka2_1:2_199,Kka2,kka2_1:2,P00552,1.2692,NO,199,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.234,-3.022,0.788,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.295029,0.00854122,1.2692 kka2_1:4_D238N,kka2_1:4_238,Kka2,kka2_1:4,P00552,1.26936,NO,238,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.83,-3.158,0.328,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.168804,0.0113863,1.26936 kka2_1:4_L53K,kka2_1:4_53,Kka2,kka2_1:4,P00552,1.26973,NO,53,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-2.681,-3.091,0.41,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.168804,0.00671168,1.26973 kka2_1:2_D180K,kka2_1:2_180,Kka2,kka2_1:2,P00552,1.26975,NO,180,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.416,-2.839,0.423,,1.03,S,a,0.75,1.5,1.27,,71.59,OAO,-2.02933,0.295029,0.00756412,1.26975 kka2_1:8_A14L,kka2_1:8_14,Kka2,kka2_1:8,P00552,1.26976,NO,14,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.837,-3.498,1.661,,0.728,G,A,0.46,0.7,,,71.59,HHH,-1.82567,0.100394,0.00706614,1.26976 kka2_1:8_A14L,kka2_1:8_14,Kka2,kka2_1:8,P00552,1.26976,NO,14,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.837,-3.498,1.661,,0.728,G,A,0.46,0.7,,,71.59,HHH,-1.82567,0.100394,0.00706614,1.26976 beta-lactamase_0_Q203L,beta-lactamase_0_203,TEM-1,beta-lactamase_0,P62593,1.26985,NO,203,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.168,-2.697,0.529,,0.47,H,A,0.64,-0.38,14.541,14.541,65.38,BPP,-1.614,0.0500837,0.00631514,1.26985 kka2_1:4_T73R,kka2_1:4_73,Kka2,kka2_1:4,P00552,1.26997,NO,73,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.51,-2.766,0.256,,0.309,H,A,0.22,0.35,1.53,,56.06,PPO,-2.02333,0.168804,0.00628605,1.26997 kka2_1:4_Q163A,kka2_1:4_163,Kka2,kka2_1:4,P00552,1.27018,NO,163,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.162,-2.603,0.441,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.168804,0.00719507,1.27018 kka2_1:2_Q163Y,kka2_1:2_163,Kka2,kka2_1:2,P00552,1.27026,NO,163,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.162,-4.27,2.108,,0.58,T,B,0.64,1.85,3.888,,64.02,BPO,-1.78333,0.295029,0.00719507,1.27026 kka2_1:8_T225H,kka2_1:8_225,Kka2,kka2_1:8,P00552,1.27026,NO,225,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.393,-3.458,1.065,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.100394,0.0113598,1.27026 kka2_1:8_T225H,kka2_1:8_225,Kka2,kka2_1:8,P00552,1.27026,NO,225,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.393,-3.458,1.065,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.100394,0.0113598,1.27026 kka2_1:8_G151N,kka2_1:8_151,Kka2,kka2_1:8,P00552,1.27032,NO,151,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.873,-2.707,1.834,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.100394,0.00339918,1.27032 kka2_1:8_G151N,kka2_1:8_151,Kka2,kka2_1:8,P00552,1.27032,NO,151,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.873,-2.707,1.834,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.100394,0.00339918,1.27032 kka2_1:8_S251F,kka2_1:8_251,Kka2,kka2_1:8,P00552,1.27052,NO,251,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.636,-4.475,1.839,,0.712,H,A,0.27,-0.25,,,71.59,APP,-2.09367,0.100394,0.0138916,1.27052 kka2_1:8_S251F,kka2_1:8_251,Kka2,kka2_1:8,P00552,1.27052,NO,251,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.636,-4.475,1.839,,0.712,H,A,0.27,-0.25,,,71.59,APP,-2.09367,0.100394,0.0138916,1.27052 kka2_1:2_A13V,kka2_1:2_13,Kka2,kka2_1:2,P00552,1.27078,NO,13,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.248,-2.845,0.597,,0.689,G,A,0.46,0.99,,,92.05,OHH,-1.646,0.295029,0.00784241,1.27078 kka2_1:4_R38K,kka2_1:4_38,Kka2,kka2_1:4,P00552,1.27118,NO,38,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.207,-3.15,1.943,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.168804,0.00372499,1.27118 beta-lactamase_0_I245D,beta-lactamase_0_245,TEM-1,beta-lactamase_0,P62593,1.27126,NO,245,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.068,,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.0500837,0.00391032,1.27126 kka2_1:4_A9N,kka2_1:4_9,Kka2,kka2_1:4,P00552,1.27135,NO,9,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.079,-2.623,0.544,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.168804,0.00273264,1.27135 kka2_1:4_V242K,kka2_1:4_242,Kka2,kka2_1:4,P00552,1.27137,NO,242,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-2.687,-2.489,-0.198,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.168804,0.0102575,1.27137 kka2_1:2_M178Y,kka2_1:2_178,Kka2,kka2_1:2,P00552,1.27146,NO,178,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-3.206,-4.367,1.161,,0.554,.,b,0.55,0.68,3.152,,71.59,BHO,-2.154,0.295029,0.00717253,1.27146 kka2_1:2_R18H,kka2_1:2_18,Kka2,kka2_1:2,P00552,1.27164,NO,18,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.055,-3.59,1.535,,0.474,T,A,1.2,0.54,8.405,8.405,71.59,ABH,-1.821,0.295029,0.00724065,1.27164 kka2_1:4_G10K,kka2_1:4_10,Kka2,kka2_1:4,P00552,1.27164,NO,10,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.921,-2.49,0.569,,,,,,,1.862,,71.59,HOP,-2.10733,0.168804,0.00289233,1.27164 kka2_1:8_A166N,kka2_1:8_166,Kka2,kka2_1:8,P00552,1.27177,NO,166,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.407,-3.048,0.641,,0.534,,B,1.04,1.03,13.995,13.995,71.59,HHO,-2.421,0.100394,0.00799912,1.27177 kka2_1:8_A166N,kka2_1:8_166,Kka2,kka2_1:8,P00552,1.27177,NO,166,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.407,-3.048,0.641,,0.534,,B,1.04,1.03,13.995,13.995,71.59,HHO,-2.421,0.100394,0.00799912,1.27177 beta-lactamase_0_T179Y,beta-lactamase_0_179,TEM-1,beta-lactamase_0,P62593,1.27178,NO,179,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.085,-4.097,3.012,,,E,B,0.22,-1.38,0.367,,73.08,PPH,-1.557,0.0500837,0.00226045,1.27178 kka2_1:4_F37W,kka2_1:4_37,Kka2,kka2_1:4,P00552,1.27201,NO,37,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.427,-2.717,1.29,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.168804,0.00586193,1.27201 kka2_1:2_L53H,kka2_1:2_53,Kka2,kka2_1:2,P00552,1.27206,NO,53,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-2.681,-4.842,2.161,,0.569,E,B,0.55,0.8,19.536,19.536,71.59,AHP,-2.47433,0.295029,0.00671168,1.27206 kka2_1:8_A176C,kka2_1:8_176,Kka2,kka2_1:8,P00552,1.27207,NO,176,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.621,-4.973,3.352,,0.806,H,A,0.46,-0.03,18.904,18.904,65.53,BHB,-2.26667,0.100394,0.0083587,1.27207 kka2_1:8_A176C,kka2_1:8_176,Kka2,kka2_1:8,P00552,1.27207,NO,176,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.621,-4.973,3.352,,0.806,H,A,0.46,-0.03,18.904,18.904,65.53,BHB,-2.26667,0.100394,0.0083587,1.27207 beta-lactamase_0_A211P,beta-lactamase_0_211,TEM-1,beta-lactamase_0,P62593,1.27212,NO,211,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.896,-3.94,2.044,,0.369,T,A,0.46,-0.69,8.527,8.527,77.62,AHA,-1.94633,0.0500837,0.00648183,1.27212 kka2_1:4_H8G,kka2_1:4_8,Kka2,kka2_1:4,P00552,1.2722,NO,8,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-2.759,-2.248,-0.511,,,,,,,,,71.59,HBH,-2.25467,0.168804,0.00256422,1.2722 kka2_1:4_Q26T,kka2_1:4_26,Kka2,kka2_1:4,P00552,1.27235,NO,26,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.18,-3.677,1.497,,0.448,E,B,0.4,0.44,5.022,,92.05,HPP,-2.11167,0.168804,0.00708962,1.27235 kka2_1:4_E149K,kka2_1:4_149,Kka2,kka2_1:4,P00552,1.27241,NO,149,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.994,-2.785,0.791,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.168804,0.00803343,1.27241 beta-lactamase_0_K232I,beta-lactamase_0_232,TEM-1,beta-lactamase_0,P62593,1.27256,NO,232,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.012,-4.053,3.041,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.0500837,0.00313441,1.27256 kka2_1:2_R173E,kka2_1:2_173,Kka2,kka2_1:2,P00552,1.27258,NO,173,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.407,-1.731,-0.676,,0.308,H,A,0.16,-0.13,15.389,15.389,65.53,HBH,-1.70533,0.295029,0.00784999,1.27258 beta-lactamase_0_A222E,beta-lactamase_0_222,TEM-1,beta-lactamase_0,P62593,1.27263,NO,222,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.103,-3.646,1.543,,0.233,H,A,0.46,-0.25,2.015,,77.62,PHH,-1.63733,0.0500837,0.00466094,1.27263 kka2_1:4_K138F,kka2_1:4_138,Kka2,kka2_1:4,P00552,1.27263,NO,138,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-2.5,-4.458,1.958,,0.594,H,A,1.3,0.98,21.267,21.267,71.59,HBB,-2.48833,0.168804,0.00628542,1.27263 kka2_1:4_M116L,kka2_1:4_116,Kka2,kka2_1:4,P00552,1.27275,NO,116,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-2.482,-1.52,-0.962,,,H,A,0.55,-0.88,1.458,,71.59,HHH,-1.63867,0.168804,0.00745147,1.27275 kka2_1:2_A172M,kka2_1:2_172,Kka2,kka2_1:2,P00552,1.27276,NO,172,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.757,-4.761,3.004,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.295029,0.0079265,1.27276 kka2_1:4_A172L,kka2_1:4_172,Kka2,kka2_1:4,P00552,1.27283,NO,172,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.757,-2.996,1.239,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.168804,0.0079265,1.27283 beta-lactamase_0_K190N,beta-lactamase_0_190,TEM-1,beta-lactamase_0,P62593,1.27285,NO,190,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.994,-2.601,0.607,,0.371,H,A,2.34,0.16,16.606,16.606,77.62,BBH,-1.64167,0.0500837,0.00574527,1.27285 kka2_1:8_L158F,kka2_1:8_158,Kka2,kka2_1:8,P00552,1.27289,NO,158,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.947,-1.154,-0.793,,0.095,.,B,0.55,0.77,1.607,,63.64,AHA,-1.25333,0.100394,0.00529068,1.27289 kka2_1:8_L158F,kka2_1:8_158,Kka2,kka2_1:8,P00552,1.27289,NO,158,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.947,-1.154,-0.793,,0.095,.,B,0.55,0.77,1.607,,63.64,AHA,-1.25333,0.100394,0.00529068,1.27289 beta-lactamase_0_E164K,beta-lactamase_0_164,TEM-1,beta-lactamase_0,P62593,1.27307,NO,164,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-0.948,-2.425,1.477,,0.011,T,B,1.04,-0.4,1.011,,64.69,HAO,-1.388,0.0500837,0.00137286,1.27307 kka2_1:4_H8N,kka2_1:4_8,Kka2,kka2_1:4,P00552,1.2731,NO,8,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-2.759,-3.586,0.827,,,,,,,,,71.59,HBH,-2.25467,0.168804,0.00256422,1.2731 beta-lactamase_0_L219E,beta-lactamase_0_219,TEM-1,beta-lactamase_0,P62593,1.27312,NO,219,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.313,-3.999,2.686,,,I,A,0.55,-0.51,6.513,6.513,74.48,HHB,-1.21533,0.0500837,0.00664345,1.27312 kka2_1:4_I254C,kka2_1:4_254,Kka2,kka2_1:4,P00552,1.27321,NO,254,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.933,-4.856,2.923,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.168804,0.0132375,1.27321 kka2_1:4_Q163W,kka2_1:4_163,Kka2,kka2_1:4,P00552,1.27325,NO,163,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.162,-5.401,3.239,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.168804,0.00719507,1.27325 kka2_1:8_A247Q,kka2_1:8_247,Kka2,kka2_1:8,P00552,1.27329,NO,247,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.459,-3.224,0.765,,1.01,S,A,0.46,0.65,18.904,18.904,92.05,HHH,-2.197,0.100394,0.0102428,1.27329 kka2_1:8_A247Q,kka2_1:8_247,Kka2,kka2_1:8,P00552,1.27329,NO,247,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.459,-3.224,0.765,,1.01,S,A,0.46,0.65,18.904,18.904,92.05,HHH,-2.197,0.100394,0.0102428,1.27329 kka2_1:4_V16D,kka2_1:4_16,Kka2,kka2_1:4,P00552,1.27352,NO,16,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-3.087,-2.706,-0.381,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.168804,0.00694011,1.27352 kka2_1:4_D101N,kka2_1:4_101,Kka2,kka2_1:4,P00552,1.27359,NO,101,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.028,-2.135,1.107,,0.213,E,B,0.75,-1.24,8.707,,63.64,PAH,-1.534,0.168804,0.00423361,1.27359 kka2_1:4_P45N,kka2_1:4_45,Kka2,kka2_1:4,P00552,1.27377,NO,45,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.774,-3.854,2.08,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.168804,0.00590481,1.27377 kka2_1:2_R202V,kka2_1:2_202,Kka2,kka2_1:2,P00552,1.27387,NO,202,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.761,-3.107,1.346,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.295029,0.00696498,1.27387 kka2_1:4_D250N,kka2_1:4_250,Kka2,kka2_1:4,P00552,1.2741,NO,250,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.015,-2.686,1.671,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.168804,0.0177103,1.2741 kka2_1:8_L7S,kka2_1:8_7,Kka2,kka2_1:8,P00552,1.27411,NO,7,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.926,-3.278,1.352,,,,,,,,,71.59,OHB,-2.12333,0.100394,0.00269456,1.27411 kka2_1:8_L7S,kka2_1:8_7,Kka2,kka2_1:8,P00552,1.27411,NO,7,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.926,-3.278,1.352,,,,,,,,,71.59,OHB,-2.12333,0.100394,0.00269456,1.27411 kka2_1:8_A176Y,kka2_1:8_176,Kka2,kka2_1:8,P00552,1.27433,NO,176,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.621,-4.408,2.787,,0.806,H,A,0.46,-0.03,18.904,18.904,65.53,BHB,-2.26667,0.100394,0.0083587,1.27433 kka2_1:8_A176Y,kka2_1:8_176,Kka2,kka2_1:8,P00552,1.27433,NO,176,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.621,-4.408,2.787,,0.806,H,A,0.46,-0.03,18.904,18.904,65.53,BHB,-2.26667,0.100394,0.0083587,1.27433 kka2_1:4_E142A,kka2_1:4_142,Kka2,kka2_1:4,P00552,1.27451,NO,142,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.221,-1.748,-0.473,,0.471,H,A,1.52,0.85,3.693,,65.53,HAB,-2.08033,0.168804,0.00748883,1.27451 kka2_1:4_L103Q,kka2_1:4_103,Kka2,kka2_1:4,P00552,1.2746,NO,103,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-2.362,-4.06,1.698,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.168804,0.00574792,1.2746 kka2_1:8_G234W,kka2_1:8_234,Kka2,kka2_1:8,P00552,1.27463,NO,234,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-2.9,-5.618,2.718,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.100394,0.00984449,1.27463 kka2_1:8_G234W,kka2_1:8_234,Kka2,kka2_1:8,P00552,1.27463,NO,234,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-2.9,-5.618,2.718,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.100394,0.00984449,1.27463 kka2_1:8_C31N,kka2_1:8_31,Kka2,kka2_1:8,P00552,1.27472,NO,31,C,N,CN,Special,Polar,5.07,5.47157,0.401575,139,121,132,11,108.5,114.1,5.6,-2.246,-3.833,1.587,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.100394,0.00681582,1.27472 kka2_1:8_C31N,kka2_1:8_31,Kka2,kka2_1:8,P00552,1.27472,NO,31,C,N,CN,Special,Polar,5.07,5.47157,0.401575,139,121,132,11,108.5,114.1,5.6,-2.246,-3.833,1.587,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.100394,0.00681582,1.27472 kka2_1:4_H106A,kka2_1:4_106,Kka2,kka2_1:4,P00552,1.27478,NO,106,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-3.13,-2.399,-0.731,,1.065,.,a,0.17,-0.95,16.74,16.74,71.59,PBH,-2.10433,0.168804,0.00730778,1.27478 kka2_1:8_C192T,kka2_1:8_192,Kka2,kka2_1:8,P00552,1.27479,NO,192,C,T,CT,Special,Polar,5.07,5.6,0.53,149,121,119,-2,108.5,116.1,7.6,-1.067,-2.666,1.599,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.100394,0.00485428,1.27479 kka2_1:8_C192T,kka2_1:8_192,Kka2,kka2_1:8,P00552,1.27479,NO,192,C,T,CT,Special,Polar,5.07,5.6,0.53,149,121,119,-2,108.5,116.1,7.6,-1.067,-2.666,1.599,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.100394,0.00485428,1.27479 kka2_1:8_L47W,kka2_1:8_47,Kka2,kka2_1:8,P00552,1.27481,NO,47,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.265,-5.21,3.945,,0.139,E,B,1.59,-0.86,5.086,,63.26,HHH,-1.77933,0.100394,0.00509386,1.27481 kka2_1:8_L47W,kka2_1:8_47,Kka2,kka2_1:8,P00552,1.27481,NO,47,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.265,-5.21,3.945,,0.139,E,B,1.59,-0.86,5.086,,63.26,HHH,-1.77933,0.100394,0.00509386,1.27481 kka2_1:8_G6W,kka2_1:8_6,Kka2,kka2_1:8,P00552,1.27483,NO,6,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.685,-5.12,3.435,,,,,,,,,71.59,AOH,-1.639,0.100394,0.00204693,1.27483 kka2_1:8_G6W,kka2_1:8_6,Kka2,kka2_1:8,P00552,1.27483,NO,6,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.685,-5.12,3.435,,,,,,,,,71.59,AOH,-1.639,0.100394,0.00204693,1.27483 kka2_1:4_R253Q,kka2_1:4_253,Kka2,kka2_1:4,P00552,1.27501,NO,253,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.356,-3.67,2.314,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.168804,0.0144195,1.27501 kka2_1:4_I246C,kka2_1:4_246,Kka2,kka2_1:4,P00552,1.27503,NO,246,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-2.008,-4.975,2.967,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.168804,0.0139479,1.27503 kka2_1:2_L47C,kka2_1:2_47,Kka2,kka2_1:2,P00552,1.27506,NO,47,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.265,-4.875,3.61,,0.139,E,B,0.55,-0.86,2.369,,63.26,HHH,-1.77933,0.295029,0.00509386,1.27506 beta-lactamase_0_P172H,beta-lactamase_0_172,TEM-1,beta-lactamase_0,P62593,1.27517,NO,172,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-0.998,-4.746,3.748,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.0500837,0.00312594,1.27517 kka2_1:4_V83Y,kka2_1:4_83,Kka2,kka2_1:4,P00552,1.27527,NO,83,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-2.567,-3.301,0.734,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.168804,0.00650486,1.27527 kka2_1:8_V242C,kka2_1:8_242,Kka2,kka2_1:8,P00552,1.27528,NO,242,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-2.687,-5.161,2.474,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.100394,0.0102575,1.27528 kka2_1:8_V242C,kka2_1:8_242,Kka2,kka2_1:8,P00552,1.27528,NO,242,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-2.687,-5.161,2.474,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.100394,0.0102575,1.27528 beta-lactamase_0_V29W,beta-lactamase_0_29,TEM-1,beta-lactamase_0,P62593,1.27535,NO,29,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-2.856,-5.465,2.609,,0.733,H,A,0.44,-0.78,21.916,21.916,93.01,HHB,-2.24733,0.0500837,0.00318969,1.27535 kka2_1:4_R44S,kka2_1:4_44,Kka2,kka2_1:4,P00552,1.27547,NO,44,R,S,RS,PositiveCharge,Polar,6.34148,5.68,-0.661478,110,174,105,-69,173.4,89,-84.4,-2.062,-2.625,0.563,,0.487,S,B,1.2,-0.35,5.71,,71.59,OBO,-1.80767,0.168804,0.00745043,1.27547 kka2_1:2_A166N,kka2_1:2_166,Kka2,kka2_1:2,P00552,1.27556,NO,166,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.407,-3.048,0.641,,0.534,.,B,0.46,1.03,23.175,23.175,71.59,HHO,-2.421,0.295029,0.00799912,1.27556 kka2_1:4_I254A,kka2_1:4_254,Kka2,kka2_1:4,P00552,1.27564,NO,254,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.933,-2.534,0.601,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.168804,0.0132375,1.27564 kka2_1:4_A255K,kka2_1:4_255,Kka2,kka2_1:4,P00552,1.27573,NO,255,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.715,-2.818,1.103,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.168804,0.0126809,1.27573 kka2_1:4_E231W,kka2_1:4_231,Kka2,kka2_1:4,P00552,1.27597,NO,231,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.002,-5.602,3.6,,0.503,H,A,1.04,-0.23,1.46,,63.26,AAH,-2.06267,0.168804,0.00732383,1.27597 kka2_1:4_P249H,kka2_1:4_249,Kka2,kka2_1:4,P00552,1.27601,NO,249,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.867,-4.971,3.104,,0.406,.,B,0.52,-0.01,,,92.05,HOA,-1.66867,0.168804,0.011045,1.27601 kka2_1:8_A9G,kka2_1:8_9,Kka2,kka2_1:8,P00552,1.27602,NO,9,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.079,-3.28,1.201,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.100394,0.00273264,1.27602 kka2_1:8_A9G,kka2_1:8_9,Kka2,kka2_1:8,P00552,1.27602,NO,9,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.079,-3.28,1.201,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.100394,0.00273264,1.27602 kka2_1:8_V80I,kka2_1:8_80,Kka2,kka2_1:8,P00552,1.2761,NO,80,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.144,-1.887,0.743,,0.358,E,B,1.48,-0.24,2.562,,63.64,HHH,-1.64633,0.100394,0.00488211,1.2761 kka2_1:8_V80I,kka2_1:8_80,Kka2,kka2_1:8,P00552,1.2761,NO,80,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.144,-1.887,0.743,,0.358,E,B,1.48,-0.24,2.562,,63.64,HHH,-1.64633,0.100394,0.00488211,1.2761 kka2_1:2_A247S,kka2_1:2_247,Kka2,kka2_1:2,P00552,1.27624,NO,247,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.459,-2.453,-0.006,,1.01,S,A,0.46,0.65,0.828,,92.05,HHH,-2.197,0.295029,0.0102428,1.27624 kka2_1:8_L223I,kka2_1:8_223,Kka2,kka2_1:8,P00552,1.27624,NO,223,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.861,-2.071,1.21,,,H,A,1.59,-1.24,1.017,,50,HHH,-0.854333,0.100394,0.00253574,1.27624 kka2_1:8_L223I,kka2_1:8_223,Kka2,kka2_1:8,P00552,1.27624,NO,223,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.861,-2.071,1.21,,,H,A,1.59,-1.24,1.017,,50,HHH,-0.854333,0.100394,0.00253574,1.27624 kka2_1:4_T73K,kka2_1:4_73,Kka2,kka2_1:4,P00552,1.27626,NO,73,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.51,-2.995,0.485,,0.309,H,A,0.22,0.35,1.53,,56.06,PPO,-2.02333,0.168804,0.00628605,1.27626 kka2_1:4_A172H,kka2_1:4_172,Kka2,kka2_1:4,P00552,1.27631,NO,172,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.757,-4.807,3.05,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.168804,0.0079265,1.27631 kka2_1:4_A166L,kka2_1:4_166,Kka2,kka2_1:4,P00552,1.27634,NO,166,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.407,-3.58,1.173,,0.534,.,B,0.46,1.03,,,71.59,HHO,-2.421,0.168804,0.00799912,1.27634 kka2_1:4_F20E,kka2_1:4_20,Kka2,kka2_1:4,P00552,1.27639,NO,20,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-3.354,-2.8,-0.554,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.168804,0.00701744,1.27639 kka2_1:4_L39G,kka2_1:4_39,Kka2,kka2_1:4,P00552,1.27639,NO,39,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.223,-2.832,1.609,,,E,B,0.55,-1.21,1.998,,71.59,BHP,-1.69167,0.168804,0.00493618,1.27639 kka2_1:4_A255D,kka2_1:4_255,Kka2,kka2_1:4,P00552,1.27659,NO,255,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.715,-2.352,0.637,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.168804,0.0126809,1.27659 kka2_1:4_A110Y,kka2_1:4_110,Kka2,kka2_1:4,P00552,1.27666,NO,110,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.064,-4.356,2.292,,0.175,H,A,0.46,-1.19,23.237,23.237,71.59,OHA,-1.91867,0.168804,0.00759851,1.27666 kka2_1:4_T146Q,kka2_1:4_146,Kka2,kka2_1:4,P00552,1.27685,NO,146,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.978,-2.971,-0.007,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.168804,0.00606474,1.27685 beta-lactamase_0_R189C,beta-lactamase_0_189,TEM-1,beta-lactamase_0,P62593,1.27717,NO,189,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.844,-5.229,3.385,,0.278,H,A,1.2,1.01,12.11,12.11,72.73,HBB,-1.668,0.0500837,0.0050699,1.27717 kka2_1:4_D156N,kka2_1:4_156,Kka2,kka2_1:4,P00552,1.27728,NO,156,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.696,-3.632,1.936,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.168804,0.00926998,1.27728 kka2_1:2_L165F,kka2_1:2_165,Kka2,kka2_1:2,P00552,1.27735,NO,165,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-2.453,-4.3,1.847,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.295029,0.00801161,1.27735 kka2_1:8_L158W,kka2_1:8_158,Kka2,kka2_1:8,P00552,1.27737,NO,158,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.947,-4.75,2.803,,0.095,.,B,0.55,0.77,1.607,,63.64,AHA,-1.25333,0.100394,0.00529068,1.27737 kka2_1:8_L158W,kka2_1:8_158,Kka2,kka2_1:8,P00552,1.27737,NO,158,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.947,-4.75,2.803,,0.095,.,B,0.55,0.77,1.607,,63.64,AHA,-1.25333,0.100394,0.00529068,1.27737 kka2_1:4_A150W,kka2_1:4_150,Kka2,kka2_1:4,P00552,1.2774,NO,150,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.949,-5.375,4.426,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.168804,0.0045009,1.2774 kka2_1:8_P12V,kka2_1:8_12,Kka2,kka2_1:8,P00552,1.27753,NO,12,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.853,-3.479,2.626,,,.,B,0.52,1.25,2.41,,48.11,POH,-1.80767,0.100394,0.00500011,1.27753 kka2_1:8_P12V,kka2_1:8_12,Kka2,kka2_1:8,P00552,1.27753,NO,12,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.853,-3.479,2.626,,,.,B,0.52,1.25,2.41,,48.11,POH,-1.80767,0.100394,0.00500011,1.27753 kka2_1:4_A168P,kka2_1:4_168,Kka2,kka2_1:4,P00552,1.27763,NO,168,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.989,-3.241,1.252,,0.67,H,A,0.46,0.15,,,64.39,OHA,-2.12933,0.168804,0.00806773,1.27763 kka2_1:4_G6A,kka2_1:4_6,Kka2,kka2_1:4,P00552,1.27772,NO,6,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.685,-2.835,1.15,,,,,,,,,71.59,AOH,-1.639,0.168804,0.00204693,1.27772 kka2_1:4_Y218M,kka2_1:4_218,Kka2,kka2_1:4,P00552,1.2779,NO,218,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-1.438,-4.695,3.257,,0.122,H,A,0.21,-0.69,1.022,,56.06,BHP,-1.17533,0.168804,0.0126098,1.2779 kka2_1:4_L60I,kka2_1:4_60,Kka2,kka2_1:4,P00552,1.27796,NO,60,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.997,-2.513,1.516,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.168804,0.00262176,1.27796 kka2_1:4_A35C,kka2_1:4_35,Kka2,kka2_1:4,P00552,1.27808,NO,35,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.127,-3.602,1.475,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.168804,0.00630016,1.27808 kka2_1:2_T146I,kka2_1:2_146,Kka2,kka2_1:2,P00552,1.2781,NO,146,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.978,-3.15,0.172,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.295029,0.00606474,1.2781 kka2_1:4_D23E,kka2_1:4_23,Kka2,kka2_1:4,P00552,1.27813,NO,23,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.459,-2.431,-0.028,,0.695,E,B,0.75,-0.65,2.416,,65.53,HAH,-1.94033,0.168804,0.007195,1.27813 kka2_1:8_R177E,kka2_1:8_177,Kka2,kka2_1:8,P00552,1.27815,NO,177,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.282,-2.717,0.435,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.100394,0.00768224,1.27815 kka2_1:8_R177E,kka2_1:8_177,Kka2,kka2_1:8,P00552,1.27815,NO,177,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.282,-2.717,0.435,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.100394,0.00768224,1.27815 kka2_1:4_A14K,kka2_1:4_14,Kka2,kka2_1:4,P00552,1.27817,NO,14,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.837,-2.596,0.759,,0.728,G,A,0.46,0.7,0.36,,71.59,HHH,-1.82567,0.168804,0.00706614,1.27817 beta-lactamase_0_D113C,beta-lactamase_0_113,TEM-1,beta-lactamase_0,P62593,1.27825,NO,113,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.829,-5.156,3.327,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.0500837,0.00474112,1.27825 kka2_1:8_G151Q,kka2_1:8_151,Kka2,kka2_1:8,P00552,1.27833,NO,151,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.873,-4.048,3.175,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.100394,0.00339918,1.27833 kka2_1:8_G151Q,kka2_1:8_151,Kka2,kka2_1:8,P00552,1.27833,NO,151,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.873,-4.048,3.175,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.100394,0.00339918,1.27833 kka2_1:8_A35T,kka2_1:8_35,Kka2,kka2_1:8,P00552,1.27839,NO,35,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.127,-2.654,0.527,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.100394,0.00630016,1.27839 kka2_1:8_A35T,kka2_1:8_35,Kka2,kka2_1:8,P00552,1.27839,NO,35,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.127,-2.654,0.527,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.100394,0.00630016,1.27839 beta-lactamase_0_Q204Y,beta-lactamase_0_204,TEM-1,beta-lactamase_0,P62593,1.27869,NO,204,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-1.382,-4.071,2.689,,0.204,H,A,0.64,0.09,2.646,,66.08,PPH,-1.49067,0.0500837,0.00364106,1.27869 kka2_1:4_T130H,kka2_1:4_130,Kka2,kka2_1:4,P00552,1.27872,NO,130,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.392,-3.566,1.174,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.168804,0.00804204,1.27872 kka2_1:8_D238T,kka2_1:8_238,Kka2,kka2_1:8,P00552,1.27881,NO,238,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.83,-2.681,-0.149,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.100394,0.0113863,1.27881 kka2_1:8_D238T,kka2_1:8_238,Kka2,kka2_1:8,P00552,1.27881,NO,238,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.83,-2.681,-0.149,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.100394,0.0113863,1.27881 kka2_1:4_L174A,kka2_1:4_174,Kka2,kka2_1:4,P00552,1.27889,NO,174,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.952,-2.507,1.555,,,H,A,0.55,-0.31,1.339,,51.89,BHB,-2.08533,0.168804,0.00438501,1.27889 kka2_1:8_A25N,kka2_1:8_25,Kka2,kka2_1:8,P00552,1.27894,NO,25,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.496,-3.071,0.575,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.100394,0.00595636,1.27894 kka2_1:8_A25N,kka2_1:8_25,Kka2,kka2_1:8,P00552,1.27894,NO,25,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.496,-3.071,0.575,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.100394,0.00595636,1.27894 kka2_1:2_A247K,kka2_1:2_247,Kka2,kka2_1:2,P00552,1.27902,NO,247,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.459,-3.008,0.549,,1.01,S,A,0.46,0.65,0.828,,92.05,HHH,-2.197,0.295029,0.0102428,1.27902 kka2_1:2_F20C,kka2_1:2_20,Kka2,kka2_1:2,P00552,1.27906,NO,20,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-3.354,-5.001,1.647,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.295029,0.00701744,1.27906 kka2_1:4_G181F,kka2_1:4_181,Kka2,kka2_1:4,P00552,1.27978,NO,181,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-2.698,-4.379,1.681,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.168804,0.00728319,1.27978 kka2_1:8_L7V,kka2_1:8_7,Kka2,kka2_1:8,P00552,1.27978,NO,7,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.926,-3.173,1.247,,,,,,,,,71.59,OHB,-2.12333,0.100394,0.00269456,1.27978 kka2_1:8_L7V,kka2_1:8_7,Kka2,kka2_1:8,P00552,1.27978,NO,7,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.926,-3.173,1.247,,,,,,,,,71.59,OHB,-2.12333,0.100394,0.00269456,1.27978 kka2_1:8_V46T,kka2_1:8_46,Kka2,kka2_1:8,P00552,1.27993,NO,46,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-2.62,-2.441,-0.179,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.100394,0.00631301,1.27993 kka2_1:8_V46T,kka2_1:8_46,Kka2,kka2_1:8,P00552,1.27993,NO,46,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-2.62,-2.441,-0.179,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.100394,0.00631301,1.27993 kka2_1:8_G234R,kka2_1:8_234,Kka2,kka2_1:8,P00552,1.27999,NO,234,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-2.9,-3.848,0.948,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.100394,0.00984449,1.27999 kka2_1:8_G234R,kka2_1:8_234,Kka2,kka2_1:8,P00552,1.27999,NO,234,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-2.9,-3.848,0.948,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.100394,0.00984449,1.27999 kka2_1:8_H8F,kka2_1:8_8,Kka2,kka2_1:8,P00552,1.28002,NO,8,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-2.759,-4.004,1.245,,,,,,,,,71.59,HBH,-2.25467,0.100394,0.00256422,1.28002 kka2_1:8_H8F,kka2_1:8_8,Kka2,kka2_1:8,P00552,1.28002,NO,8,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-2.759,-4.004,1.245,,,,,,,,,71.59,HBH,-2.25467,0.100394,0.00256422,1.28002 kka2_1:8_D238L,kka2_1:8_238,Kka2,kka2_1:8,P00552,1.28003,NO,238,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.83,-3.612,0.782,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.100394,0.0113863,1.28003 kka2_1:8_D238L,kka2_1:8_238,Kka2,kka2_1:8,P00552,1.28003,NO,238,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.83,-3.612,0.782,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.100394,0.0113863,1.28003 kka2_1:8_A25T,kka2_1:8_25,Kka2,kka2_1:8,P00552,1.28008,NO,25,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.496,-2.626,0.13,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.100394,0.00595636,1.28008 kka2_1:8_A25T,kka2_1:8_25,Kka2,kka2_1:8,P00552,1.28008,NO,25,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.496,-2.626,0.13,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.100394,0.00595636,1.28008 kka2_1:4_D134A,kka2_1:4_134,Kka2,kka2_1:4,P00552,1.28021,NO,134,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.969,-3.306,2.337,,0.421,B,B,0.75,0.31,0.733,,49.62,HAB,-1.057,0.168804,0.00270812,1.28021 kka2_1:4_T125G,kka2_1:4_125,Kka2,kka2_1:4,P00552,1.28022,NO,125,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.622,-2.508,-0.114,,0.791,T,A,0.82,0.33,1.612,,92.05,BPH,-1.56933,0.168804,0.00821755,1.28022 beta-lactamase_0_R41Q,beta-lactamase_0_41,TEM-1,beta-lactamase_0,P62593,1.2803,NO,41,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-0.942,-3.498,2.556,,0.321,E,B,1.2,-0.07,2.68,,65.03,HBH,-1.30267,0.0500837,0.00123327,1.2803 kka2_1:4_A9Q,kka2_1:4_9,Kka2,kka2_1:4,P00552,1.28036,NO,9,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.079,-3.919,1.84,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.168804,0.00273264,1.28036 kka2_1:8_Q163L,kka2_1:8_163,Kka2,kka2_1:8,P00552,1.28078,NO,163,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.162,-1.74,-0.422,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.100394,0.00719507,1.28078 kka2_1:8_Q163L,kka2_1:8_163,Kka2,kka2_1:8,P00552,1.28078,NO,163,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.162,-1.74,-0.422,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.100394,0.00719507,1.28078 kka2_1:2_L53Q,kka2_1:2_53,Kka2,kka2_1:2,P00552,1.281,NO,53,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-2.681,-2.601,-0.08,,0.569,E,B,0.55,0.8,19.536,19.536,71.59,AHP,-2.47433,0.295029,0.00671168,1.281 kka2_1:2_I254M,kka2_1:2_254,Kka2,kka2_1:2,P00552,1.28112,NO,254,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.933,-2.224,0.291,,0.135,H,A,1.52,-0.6,2.562,,71.59,BHH,-1.668,0.295029,0.0132375,1.28112 kka2_1:8_A71Q,kka2_1:8_71,Kka2,kka2_1:8,P00552,1.28112,NO,71,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.824,-2.665,0.841,,0.553,H,A,0.46,0.08,18.64,18.64,64.39,HHP,-1.74033,0.100394,0.00727707,1.28112 kka2_1:8_A71Q,kka2_1:8_71,Kka2,kka2_1:8,P00552,1.28112,NO,71,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.824,-2.665,0.841,,0.553,H,A,0.46,0.08,18.64,18.64,64.39,HHP,-1.74033,0.100394,0.00727707,1.28112 beta-lactamase_0_E164S,beta-lactamase_0_164,TEM-1,beta-lactamase_0,P62593,1.28129,NO,164,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-0.948,-3.21,2.262,,0.011,T,B,1.04,-0.4,1.011,,64.69,HAO,-1.388,0.0500837,0.00137286,1.28129 kka2_1:4_D33K,kka2_1:4_33,Kka2,kka2_1:4,P00552,1.28129,NO,33,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.186,-3.557,1.371,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.168804,0.00633568,1.28129 beta-lactamase_0_A211S,beta-lactamase_0_211,TEM-1,beta-lactamase_0,P62593,1.28136,NO,211,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-1.896,-2.788,0.892,,0.369,T,A,0.46,-0.69,8.527,8.527,77.62,AHA,-1.94633,0.0500837,0.00648183,1.28136 kka2_1:4_P179V,kka2_1:4_179,Kka2,kka2_1:4,P00552,1.28144,NO,179,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-0.974,-3.463,2.489,,0.113,,B,0.52,0.69,10.913,10.913,56.06,HOA,-2.19867,0.168804,0.00298346,1.28144 kka2_1:2_G10T,kka2_1:2_10,Kka2,kka2_1:2,P00552,1.28145,NO,10,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.921,-3.48,1.559,,,,,,,2.192,,71.59,HOP,-2.10733,0.295029,0.00289233,1.28145 kka2_1:2_V84K,kka2_1:2_84,Kka2,kka2_1:2,P00552,1.2815,NO,84,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-2.279,-3.653,1.374,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.295029,0.00724019,1.2815 kka2_1:8_Q61A,kka2_1:8_61,Kka2,kka2_1:8,P00552,1.28155,NO,61,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.982,-1.987,-0.995,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.100394,0.00612092,1.28155 kka2_1:8_Q61A,kka2_1:8_61,Kka2,kka2_1:8,P00552,1.28155,NO,61,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.982,-1.987,-0.995,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.100394,0.00612092,1.28155 kka2_1:2_R18N,kka2_1:2_18,Kka2,kka2_1:2,P00552,1.28174,NO,18,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.055,-3.899,1.844,,0.474,T,A,1.2,0.54,8.405,8.405,71.59,ABH,-1.821,0.295029,0.00724065,1.28174 kka2_1:4_L47R,kka2_1:4_47,Kka2,kka2_1:4,P00552,1.28193,NO,47,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.265,-2.763,1.498,,0.139,E,B,0.55,-0.86,2.369,,63.26,HHH,-1.77933,0.168804,0.00509386,1.28193 beta-lactamase_0_Q267I,beta-lactamase_0_267,TEM-1,beta-lactamase_0,P62593,1.28199,NO,267,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.0500837,0.0102128,1.28199 kka2_1:4_T73I,kka2_1:4_73,Kka2,kka2_1:4,P00552,1.282,NO,73,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.51,-3.77,1.26,,0.309,H,A,0.22,0.35,1.53,,56.06,PPO,-2.02333,0.168804,0.00628605,1.282 kka2_1:2_G21N,kka2_1:2_21,Kka2,kka2_1:2,P00552,1.28216,NO,21,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.368,-3.58,2.212,,0.586,T,l,0.29,-0.75,2.026,,71.59,HOH,-2.10167,0.295029,0.00709648,1.28216 kka2_1:4_A191M,kka2_1:4_191,Kka2,kka2_1:4,P00552,1.28225,NO,191,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.831,-4.572,3.741,,,.,b,0.46,-0.94,2.046,,50,AHO,-0.868667,0.168804,0.00338807,1.28225 kka2_1:4_R143H,kka2_1:4_143,Kka2,kka2_1:4,P00552,1.28225,NO,143,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.525,-3.575,1.05,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.168804,0.00662247,1.28225 kka2_1:4_H8Y,kka2_1:4_8,Kka2,kka2_1:4,P00552,1.28228,NO,8,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-2.759,-3.943,1.184,,,,,,,,,71.59,HBH,-2.25467,0.168804,0.00256422,1.28228 kka2_1:4_V83A,kka2_1:4_83,Kka2,kka2_1:4,P00552,1.28246,NO,83,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-2.567,-2.453,-0.114,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.168804,0.00650486,1.28246 kka2_1:4_I2D,kka2_1:4_2,Kka2,kka2_1:4,P00552,1.28248,NO,2,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.787,-3.608,1.821,,,,,,,,,71.59,HHA,-1.92433,0.168804,0.00246644,1.28248 beta-lactamase_0_N130Q,beta-lactamase_0_130,TEM-1,beta-lactamase_0,P62593,1.28268,NO,130,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-0.798,-3.674,2.876,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.0500837,0.000683376,1.28268 kka2_1:2_G234N,kka2_1:2_234,Kka2,kka2_1:2,P00552,1.28268,NO,234,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-2.9,-3.105,0.205,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.295029,0.00984449,1.28268 kka2_1:4_A25V,kka2_1:4_25,Kka2,kka2_1:4,P00552,1.28269,NO,25,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.496,-2.849,0.353,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.168804,0.00595636,1.28269 kka2_1:4_F264Y,kka2_1:4_264,Kka2,kka2_1:4,P00552,1.28275,NO,264,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.02,-2.016,0.996,,0.296,,?,1.62,0.02,1.93,,71.59,HHO,-0.9655,0.168804,,1.28275 kka2_1:4_D5T,kka2_1:4_5,Kka2,kka2_1:4,P00552,1.28294,NO,5,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.306,-3.232,1.926,,,,,,,,,71.59,PAO,-1.784,0.168804,0.00222864,1.28294 beta-lactamase_0_E272K,beta-lactamase_0_272,TEM-1,beta-lactamase_0,P62593,1.283,NO,272,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.0500837,0.00545371,1.283 kka2_1:4_A150L,kka2_1:4_150,Kka2,kka2_1:4,P00552,1.28326,NO,150,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-0.949,-3.346,2.397,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.168804,0.0045009,1.28326 kka2_1:4_E160D,kka2_1:4_160,Kka2,kka2_1:4,P00552,1.28328,NO,160,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-1.683,-1.462,-0.221,,0.989,G,A,1.04,2.28,2.531,,71.59,AAA,-1.36133,0.168804,0.00935762,1.28328 kka2_1:8_R18T,kka2_1:8_18,Kka2,kka2_1:8,P00552,1.2833,NO,18,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.055,-2.928,0.873,,0.474,T,A,1.2,0.54,19.629,19.629,71.59,ABH,-1.821,0.100394,0.00724065,1.2833 kka2_1:8_R18T,kka2_1:8_18,Kka2,kka2_1:8,P00552,1.2833,NO,18,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.055,-2.928,0.873,,0.474,T,A,1.2,0.54,19.629,19.629,71.59,ABH,-1.821,0.100394,0.00724065,1.2833 kka2_1:8_L7C,kka2_1:8_7,Kka2,kka2_1:8,P00552,1.28337,NO,7,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.926,-4.785,2.859,,,,,,,,,71.59,OHB,-2.12333,0.100394,0.00269456,1.28337 kka2_1:8_L7C,kka2_1:8_7,Kka2,kka2_1:8,P00552,1.28337,NO,7,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.926,-4.785,2.859,,,,,,,,,71.59,OHB,-2.12333,0.100394,0.00269456,1.28337 beta-lactamase_0_S201C,beta-lactamase_0_201,TEM-1,beta-lactamase_0,P62593,1.28345,NO,201,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.183,-4.753,3.57,,0.064,H,A,0.27,-0.07,3.54,,64.69,HPB,-1.451,0.0500837,0.00198815,1.28345 kka2_1:4_T28D,kka2_1:4_28,Kka2,kka2_1:4,P00552,1.28362,NO,28,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.883,-2.685,0.802,,0.353,S,B,0.82,2.02,4.415,,63.64,PPH,-1.74467,0.168804,0.00743084,1.28362 kka2_1:8_S40N,kka2_1:8_40,Kka2,kka2_1:8,P00552,1.28373,NO,40,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.645,-3.752,1.107,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.100394,0.00693477,1.28373 kka2_1:8_S40N,kka2_1:8_40,Kka2,kka2_1:8,P00552,1.28373,NO,40,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.645,-3.752,1.107,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.100394,0.00693477,1.28373 WW_domain_L190K,WW_domain_190,Yap65,WW_domain,P46937,1.2842,NO,190,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.404,-3.616,2.212,5.53598,,,,,,0.645,,56.55,HHP,-1.51833,0.153962,0.00249186,1.2842 kka2_1:4_Q4C,kka2_1:4_4,Kka2,kka2_1:4,P00552,1.28423,NO,4,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.361,-4.857,2.496,,,,,,,2.026,,71.59,APA,-1.95533,0.168804,0.00239179,1.28423 kka2_1:4_E230T,kka2_1:4_230,Kka2,kka2_1:4,P00552,1.28424,NO,230,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.672,-3.072,0.4,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.168804,0.00920051,1.28424 kka2_1:2_A25T,kka2_1:2_25,Kka2,kka2_1:2,P00552,1.28428,NO,25,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.496,-2.626,0.13,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.295029,0.00595636,1.28428 kka2_1:8_A56G,kka2_1:8_56,Kka2,kka2_1:8,P00552,1.28447,NO,56,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.083,-2.527,0.444,,0.796,T,A,0.46,1.39,10.511,,71.59,OHH,-1.86867,0.100394,0.00717715,1.28447 kka2_1:8_A56G,kka2_1:8_56,Kka2,kka2_1:8,P00552,1.28447,NO,56,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.083,-2.527,0.444,,0.796,T,A,0.46,1.39,10.511,,71.59,OHH,-1.86867,0.100394,0.00717715,1.28447 kka2_1:8_G234M,kka2_1:8_234,Kka2,kka2_1:8,P00552,1.28447,NO,234,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-2.9,-4.839,1.939,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.100394,0.00984449,1.28447 kka2_1:8_G234M,kka2_1:8_234,Kka2,kka2_1:8,P00552,1.28447,NO,234,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-2.9,-4.839,1.939,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.100394,0.00984449,1.28447 kka2_1:8_E199C,kka2_1:8_199,Kka2,kka2_1:8,P00552,1.28464,NO,199,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.234,-3.64,1.406,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.100394,0.00854122,1.28464 kka2_1:8_E199C,kka2_1:8_199,Kka2,kka2_1:8,P00552,1.28464,NO,199,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.234,-3.64,1.406,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.100394,0.00854122,1.28464 beta-lactamase_0_Q203D,beta-lactamase_0_203,TEM-1,beta-lactamase_0,P62593,1.28473,NO,203,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.168,-2.512,0.344,,0.47,H,A,0.64,-0.38,14.541,14.541,65.38,BPP,-1.614,0.0500837,0.00631514,1.28473 kka2_1:4_M178H,kka2_1:4_178,Kka2,kka2_1:4,P00552,1.28473,NO,178,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-3.206,-4.758,1.552,,0.554,.,b,0.55,0.68,9.913,9.913,71.59,BHO,-2.154,0.168804,0.00717253,1.28473 kka2_1:8_R173M,kka2_1:8_173,Kka2,kka2_1:8,P00552,1.28479,NO,173,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.407,-4.764,2.357,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.100394,0.00784999,1.28479 kka2_1:8_R173M,kka2_1:8_173,Kka2,kka2_1:8,P00552,1.28479,NO,173,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.407,-4.764,2.357,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.100394,0.00784999,1.28479 kka2_1:8_L47H,kka2_1:8_47,Kka2,kka2_1:8,P00552,1.28482,NO,47,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.265,-4.833,3.568,,0.139,E,B,1.59,-0.86,5.086,,63.26,HHH,-1.77933,0.100394,0.00509386,1.28482 kka2_1:8_L47H,kka2_1:8_47,Kka2,kka2_1:8,P00552,1.28482,NO,47,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.265,-4.833,3.568,,0.139,E,B,1.59,-0.86,5.086,,63.26,HHH,-1.77933,0.100394,0.00509386,1.28482 kka2_1:2_E3K,kka2_1:2_3,Kka2,kka2_1:2,P00552,1.28505,NO,3,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.199,-3.312,1.113,,,,,,,7.22,,92.05,HAP,-2.11567,0.295029,0.00267607,1.28505 beta-lactamase_0_L100M,beta-lactamase_0_100,TEM-1,beta-lactamase_0,P62593,1.28507,NO,100,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.218,-4.039,2.821,,0.343,,B,0.55,0.13,1.373,,63.29,AHH,-1.23467,0.0500837,0.00413885,1.28507 kka2_1:2_K138R,kka2_1:2_138,Kka2,kka2_1:2,P00552,1.28509,NO,138,K,R,KR,PositiveCharge,PositiveCharge,9.74,6.34148,-3.39852,26,146,174,28,168.6,173.4,4.8,-2.5,-3.18,0.68,,0.594,H,A,2.34,0.98,21.038,21.038,71.59,HBB,-2.48833,0.295029,0.00628542,1.28509 kka2_1:4_V16H,kka2_1:4_16,Kka2,kka2_1:4,P00552,1.28535,NO,16,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-3.087,-3.512,0.425,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.168804,0.00694011,1.28535 kka2_1:8_T73V,kka2_1:8_73,Kka2,kka2_1:8,P00552,1.28537,NO,73,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.51,-2.513,0.003,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.100394,0.00628605,1.28537 kka2_1:8_T73V,kka2_1:8_73,Kka2,kka2_1:8,P00552,1.28537,NO,73,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.51,-2.513,0.003,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.100394,0.00628605,1.28537 kka2_1:4_Q61W,kka2_1:4_61,Kka2,kka2_1:4,P00552,1.28538,NO,61,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.982,-5.59,2.608,,0.591,H,A,0.64,0.41,3.484,,65.53,HPA,-1.85667,0.168804,0.00612092,1.28538 beta-lactamase_0_N98C,beta-lactamase_0_98,TEM-1,beta-lactamase_0,P62593,1.28545,NO,98,N,C,NC,Polar,Special,5.47157,5.07,-0.401575,139,132,121,-11,114.1,108.5,-5.6,-2.973,-5.105,2.132,,0.963,G,A,0.61,1.35,14.853,14.853,77.62,PPA,-2.07867,0.0500837,0.00505389,1.28545 kka2_1:4_V80P,kka2_1:4_80,Kka2,kka2_1:4,P00552,1.28559,NO,80,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.144,-2.863,1.719,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.168804,0.00488211,1.28559 kka2_1:8_K175I,kka2_1:8_175,Kka2,kka2_1:8,P00552,1.2856,NO,175,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-2.897,-2.932,0.035,,0.579,H,A,2.34,0.51,15.316,15.316,71.59,HBH,-1.82333,0.100394,0.00693093,1.2856 kka2_1:8_K175I,kka2_1:8_175,Kka2,kka2_1:8,P00552,1.2856,NO,175,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-2.897,-2.932,0.035,,0.579,H,A,2.34,0.51,15.316,15.316,71.59,HBH,-1.82333,0.100394,0.00693093,1.2856 kka2_1:4_L53Q,kka2_1:4_53,Kka2,kka2_1:4,P00552,1.28574,NO,53,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-2.681,-2.601,-0.08,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.168804,0.00671168,1.28574 kka2_1:4_S54Y,kka2_1:4_54,Kka2,kka2_1:4,P00552,1.28575,NO,54,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.471,-4.321,1.85,,0.408,S,b,0.27,1.01,17.332,17.332,71.59,HPO,-2.259,0.168804,0.00782867,1.28575 kka2_1:4_D33E,kka2_1:4_33,Kka2,kka2_1:4,P00552,1.28586,NO,33,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.186,-2.762,0.576,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.168804,0.00633568,1.28586 beta-lactamase_0_E87L,beta-lactamase_0_87,TEM-1,beta-lactamase_0,P62593,1.28591,NO,87,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.421,-2.529,1.108,,0.048,,B,1.04,0.92,1.159,,64.69,PAP,-1.969,0.0500837,0.00337888,1.28591 beta-lactamase_0_E87V,beta-lactamase_0_87,TEM-1,beta-lactamase_0,P62593,1.28606,NO,87,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.421,-2.385,0.964,,0.048,,B,1.04,0.92,1.159,,64.69,PAP,-1.969,0.0500837,0.00337888,1.28606 kka2_1:8_S251T,kka2_1:8_251,Kka2,kka2_1:8,P00552,1.28606,NO,251,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.636,-3.052,0.416,,0.712,H,A,0.27,-0.25,,,71.59,APP,-2.09367,0.100394,0.0138916,1.28606 kka2_1:8_S251T,kka2_1:8_251,Kka2,kka2_1:8,P00552,1.28606,NO,251,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.636,-3.052,0.416,,0.712,H,A,0.27,-0.25,,,71.59,APP,-2.09367,0.100394,0.0138916,1.28606 kka2_1:4_R143A,kka2_1:4_143,Kka2,kka2_1:4,P00552,1.2861,NO,143,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.525,-2.1,-0.425,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.168804,0.00662247,1.2861 kka2_1:8_D238Q,kka2_1:8_238,Kka2,kka2_1:8,P00552,1.2861,NO,238,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.83,-2.348,-0.482,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.100394,0.0113863,1.2861 kka2_1:8_D238Q,kka2_1:8_238,Kka2,kka2_1:8,P00552,1.2861,NO,238,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.83,-2.348,-0.482,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.100394,0.0113863,1.2861 beta-lactamase_0_E61K,beta-lactamase_0_61,TEM-1,beta-lactamase_0,P62593,1.2862,NO,61,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.115,-3.46,1.345,,0.775,T,a,1.04,1.29,34.763,34.763,77.62,OAA,-1.92567,0.0500837,0.00440955,1.2862 kka2_1:8_A176R,kka2_1:8_176,Kka2,kka2_1:8,P00552,1.28631,NO,176,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.621,-2.52,0.899,,0.806,H,A,0.46,-0.03,18.904,18.904,65.53,BHB,-2.26667,0.100394,0.0083587,1.28631 kka2_1:8_A176R,kka2_1:8_176,Kka2,kka2_1:8,P00552,1.28631,NO,176,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.621,-2.52,0.899,,0.806,H,A,0.46,-0.03,18.904,18.904,65.53,BHB,-2.26667,0.100394,0.0083587,1.28631 kka2_1:2_G6C,kka2_1:2_6,Kka2,kka2_1:2,P00552,1.28653,NO,6,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.685,-2.485,0.8,,,,,,,,,71.59,AOH,-1.639,0.295029,0.00204693,1.28653 kka2_1:2_A176Y,kka2_1:2_176,Kka2,kka2_1:2,P00552,1.28654,NO,176,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.621,-4.408,2.787,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.295029,0.0083587,1.28654 kka2_1:8_A191H,kka2_1:8_191,Kka2,kka2_1:8,P00552,1.28654,NO,191,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.831,-4.743,3.912,,,,b,1.04,-0.94,1.306,,50,AHO,-0.868667,0.100394,0.00338807,1.28654 kka2_1:8_A191H,kka2_1:8_191,Kka2,kka2_1:8,P00552,1.28654,NO,191,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.831,-4.743,3.912,,,,b,1.04,-0.94,1.306,,50,AHO,-0.868667,0.100394,0.00338807,1.28654 kka2_1:2_S251C,kka2_1:2_251,Kka2,kka2_1:2,P00552,1.28662,NO,251,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.636,-5.186,2.55,,0.712,H,A,0.27,-0.25,32.832,32.832,71.59,APP,-2.09367,0.295029,0.0138916,1.28662 kka2_1:2_A168K,kka2_1:2_168,Kka2,kka2_1:2,P00552,1.28667,NO,168,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.989,-2.846,0.857,,0.67,H,A,0.46,0.15,25.546,25.546,64.39,OHA,-2.12933,0.295029,0.00806773,1.28667 kka2_1:4_L53E,kka2_1:4_53,Kka2,kka2_1:4,P00552,1.28669,NO,53,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-2.681,-2.451,-0.23,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.168804,0.00671168,1.28669 beta-lactamase_0_Y95Q,beta-lactamase_0_95,TEM-1,beta-lactamase_0,P62593,1.28678,NO,95,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-1.715,-4.267,2.552,,0.122,,b,0.21,-0.37,2.914,,77.62,BHP,-2.16167,0.0500837,0.00479449,1.28678 kka2_1:4_G74N,kka2_1:4_74,Kka2,kka2_1:4,P00552,1.28685,NO,74,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.18,-2.406,1.226,,0.621,T,l,0.75,0.2,1.032,,64.39,POH,-1.91667,0.168804,0.00587035,1.28685 beta-lactamase_0_M127I,beta-lactamase_0_127,TEM-1,beta-lactamase_0,P62593,1.28693,NO,127,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-2.251,-2.439,0.188,,0.312,S,A,0.55,0.32,9.35,9.35,72.73,PHP,-1.40433,0.0500837,0.00437927,1.28693 kka2_1:4_A110L,kka2_1:4_110,Kka2,kka2_1:4,P00552,1.28698,NO,110,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.064,-2.329,0.265,,0.175,H,A,0.46,-1.19,23.237,23.237,71.59,OHA,-1.91867,0.168804,0.00759851,1.28698 kka2_1:4_E199S,kka2_1:4_199,Kka2,kka2_1:4,P00552,1.28701,NO,199,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.234,-2.389,0.155,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.168804,0.00854122,1.28701 kka2_1:8_D33K,kka2_1:8_33,Kka2,kka2_1:8,P00552,1.28706,NO,33,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.186,-3.557,1.371,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.100394,0.00633568,1.28706 kka2_1:8_D33K,kka2_1:8_33,Kka2,kka2_1:8,P00552,1.28706,NO,33,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.186,-3.557,1.371,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.100394,0.00633568,1.28706 kka2_1:2_R143D,kka2_1:2_143,Kka2,kka2_1:2,P00552,1.2872,NO,143,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.525,-2.588,0.063,,0.325,H,A,0.16,1.22,14.853,14.853,65.53,ABH,-1.86833,0.295029,0.00662247,1.2872 kka2_1:8_I2H,kka2_1:8_2,Kka2,kka2_1:8,P00552,1.2872,NO,2,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.787,-4.676,2.889,,,,,,,,,71.59,HHA,-1.92433,0.100394,0.00246644,1.2872 kka2_1:8_I2H,kka2_1:8_2,Kka2,kka2_1:8,P00552,1.2872,NO,2,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.787,-4.676,2.889,,,,,,,,,71.59,HHA,-1.92433,0.100394,0.00246644,1.2872 kka2_1:4_S251I,kka2_1:4_251,Kka2,kka2_1:4,P00552,1.28721,NO,251,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.636,-4.095,1.459,,0.712,H,A,0.77,-0.25,,,71.59,APP,-2.09367,0.168804,0.0138916,1.28721 kka2_1:4_A247L,kka2_1:4_247,Kka2,kka2_1:4,P00552,1.28755,NO,247,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.459,-2.722,0.263,,1.01,S,A,0.46,0.65,,,92.05,HHH,-2.197,0.168804,0.0102428,1.28755 kka2_1:2_I2Y,kka2_1:2_2,Kka2,kka2_1:2,P00552,1.28759,NO,2,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.787,-3.837,2.05,,,,,,,5.773,,71.59,HHA,-1.92433,0.295029,0.00246644,1.28759 kka2_1:2_D238T,kka2_1:2_238,Kka2,kka2_1:2,P00552,1.28769,NO,238,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.83,-2.681,-0.149,,0.604,H,A,0.75,-0.33,22.789,22.789,92.05,HAB,-2.633,0.295029,0.0113863,1.28769 beta-lactamase_0_C75I,beta-lactamase_0_75,TEM-1,beta-lactamase_0,P62593,1.28795,NO,75,C,I,CI,Special,Hydrophobic,5.07,6.02,0.95,198,121,131,10,108.5,166.7,58.2,-1.245,-3.708,2.463,,,H,A,0.46,-0.87,2.256,,50,HOO,-1.24333,0.0500837,0.0034616,1.28795 beta-lactamase_0_R176C,beta-lactamase_0_176,TEM-1,beta-lactamase_0,P62593,1.288,NO,176,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-0.863,-5.087,4.224,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.0500837,0.00105554,1.288 kka2_1:8_A166D,kka2_1:8_166,Kka2,kka2_1:8,P00552,1.28808,NO,166,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.407,-2.968,0.561,,0.534,,B,1.04,1.03,13.995,13.995,71.59,HHO,-2.421,0.100394,0.00799912,1.28808 kka2_1:8_A166D,kka2_1:8_166,Kka2,kka2_1:8,P00552,1.28808,NO,166,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.407,-2.968,0.561,,0.534,,B,1.04,1.03,13.995,13.995,71.59,HHO,-2.421,0.100394,0.00799912,1.28808 beta-lactamase_0_Q267E,beta-lactamase_0_267,TEM-1,beta-lactamase_0,P62593,1.28814,NO,267,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.0500837,0.0102128,1.28814 beta-lactamase_0_I258V,beta-lactamase_0_258,TEM-1,beta-lactamase_0,P62593,1.28827,NO,258,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.975,-2.547,0.572,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.0500837,0.007931,1.28827 kka2_1:8_A248R,kka2_1:8_248,Kka2,kka2_1:8,P00552,1.28827,NO,248,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.124,-2.856,0.732,,0.825,S,b,1.04,0.46,11.329,11.329,92.05,HHO,-2.15,0.100394,0.0125484,1.28827 kka2_1:8_A248R,kka2_1:8_248,Kka2,kka2_1:8,P00552,1.28827,NO,248,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.124,-2.856,0.732,,0.825,S,b,1.04,0.46,11.329,11.329,92.05,HHO,-2.15,0.100394,0.0125484,1.28827 kka2_1:4_V46P,kka2_1:4_46,Kka2,kka2_1:4,P00552,1.28857,NO,46,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-2.62,-2.348,-0.272,,0.192,.,B,0.44,-1.12,9.564,,92.05,OHH,-1.88633,0.168804,0.00631301,1.28857 kka2_1:4_A71R,kka2_1:4_71,Kka2,kka2_1:4,P00552,1.28877,NO,71,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.824,-2.453,0.629,,0.553,H,A,0.46,0.08,5.76,,64.39,HHP,-1.74033,0.168804,0.00727707,1.28877 kka2_1:8_A108P,kka2_1:8_108,Kka2,kka2_1:8,P00552,1.28898,NO,108,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.061,-2.19,0.129,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.100394,0.00751209,1.28898 kka2_1:8_A108P,kka2_1:8_108,Kka2,kka2_1:8,P00552,1.28898,NO,108,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.061,-2.19,0.129,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.100394,0.00751209,1.28898 kka2_1:4_G6N,kka2_1:4_6,Kka2,kka2_1:4,P00552,1.28914,NO,6,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.685,-3.547,1.862,,,,,,,,,71.59,AOH,-1.639,0.168804,0.00204693,1.28914 kka2_1:4_V153M,kka2_1:4_153,Kka2,kka2_1:4,P00552,1.28915,NO,153,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.092,-4.165,3.073,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.168804,0.00501119,1.28915 WW_domain_V171N,WW_domain_171,Yap65,WW_domain,P46937,1.28916,NO,171,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.547,-3.963,2.416,,,,,,,3.459,,70.24,AHO,-1.265,0.153962,0.00184125,1.28916 kka2_1:2_T146Q,kka2_1:2_146,Kka2,kka2_1:2,P00552,1.28917,NO,146,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.978,-2.971,-0.007,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.295029,0.00606474,1.28917 kka2_1:4_Q26R,kka2_1:4_26,Kka2,kka2_1:4,P00552,1.28928,NO,26,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.18,-1.791,-0.389,,0.448,E,B,0.4,0.44,5.022,,92.05,HPP,-2.11167,0.168804,0.00708962,1.28928 kka2_1:4_Q26Y,kka2_1:4_26,Kka2,kka2_1:4,P00552,1.28947,NO,26,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.18,-4.333,2.153,,0.448,E,B,0.4,0.44,5.022,,92.05,HPP,-2.11167,0.168804,0.00708962,1.28947 kka2_1:4_S251C,kka2_1:4_251,Kka2,kka2_1:4,P00552,1.28948,NO,251,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.636,-5.186,2.55,,0.712,H,A,0.77,-0.25,,,71.59,APP,-2.09367,0.168804,0.0138916,1.28948 kka2_1:4_L103H,kka2_1:4_103,Kka2,kka2_1:4,P00552,1.28951,NO,103,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-2.362,-4.862,2.5,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.168804,0.00574792,1.28951 beta-lactamase_0_T147E,beta-lactamase_0_147,TEM-1,beta-lactamase_0,P62593,1.28965,NO,147,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.149,-3.519,2.37,,0.281,H,A,0.22,-0.68,3.487,,64.34,HPH,-1.456,0.0500837,0.00226017,1.28965 kka2_1:8_R177T,kka2_1:8_177,Kka2,kka2_1:8,P00552,1.28975,NO,177,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.282,-2.275,-0.007,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.100394,0.00768224,1.28975 kka2_1:8_R177T,kka2_1:8_177,Kka2,kka2_1:8,P00552,1.28975,NO,177,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.282,-2.275,-0.007,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.100394,0.00768224,1.28975 kka2_1:4_A248L,kka2_1:4_248,Kka2,kka2_1:4,P00552,1.28984,NO,248,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.124,-3.034,0.91,,0.825,S,b,0.46,0.46,,,92.05,HHO,-2.15,0.168804,0.0125484,1.28984 kka2_1:2_E149Q,kka2_1:2_149,Kka2,kka2_1:2,P00552,1.28988,NO,149,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.994,-2.493,0.499,,0.674,H,A,1.04,1.63,15.361,15.361,71.59,HAH,-1.59667,0.295029,0.00803343,1.28988 kka2_1:8_R177I,kka2_1:8_177,Kka2,kka2_1:8,P00552,1.2899,NO,177,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.282,-3.929,1.647,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.100394,0.00768224,1.2899 kka2_1:8_R177I,kka2_1:8_177,Kka2,kka2_1:8,P00552,1.2899,NO,177,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.282,-3.929,1.647,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.100394,0.00768224,1.2899 kka2_1:8_E230H,kka2_1:8_230,Kka2,kka2_1:8,P00552,1.29011,NO,230,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.672,-2.411,-0.261,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.100394,0.00920051,1.29011 kka2_1:8_E230H,kka2_1:8_230,Kka2,kka2_1:8,P00552,1.29011,NO,230,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.672,-2.411,-0.261,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.100394,0.00920051,1.29011 kka2_1:4_Q100V,kka2_1:4_100,Kka2,kka2_1:4,P00552,1.29019,NO,100,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.77,-2.771,0.001,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.168804,0.0066405,1.29019 WW_domain_V171P,WW_domain_171,Yap65,WW_domain,P46937,1.29019,NO,171,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.547,-3.798,2.251,,,,,,,3.459,,70.24,AHO,-1.265,0.153962,0.00184125,1.29019 kka2_1:4_Q26V,kka2_1:4_26,Kka2,kka2_1:4,P00552,1.29028,NO,26,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.18,-3.715,1.535,,0.448,E,B,0.4,0.44,5.022,,92.05,HPP,-2.11167,0.168804,0.00708962,1.29028 kka2_1:2_R177H,kka2_1:2_177,Kka2,kka2_1:2,P00552,1.29051,NO,177,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.282,-3.561,1.279,,0.521,T,A,1.2,0.16,1.842,,63.64,HBH,-2.36967,0.295029,0.00768224,1.29051 kka2_1:2_C209A,kka2_1:2_209,Kka2,kka2_1:2,P00552,1.29091,NO,209,C,A,CA,Special,Hydrophobic,5.07,6,0.93,195,121,89,-32,108.5,88.6,-19.9,-0.906,-2.925,2.019,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.295029,0.00260862,1.29091 kka2_1:4_G43K,kka2_1:4_43,Kka2,kka2_1:4,P00552,1.29093,NO,43,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.587,-3.606,2.019,,0.862,T,l,0.75,-0.67,2.247,,63.26,POB,-2.18533,0.168804,0.0071925,1.29093 kka2_1:4_R18H,kka2_1:4_18,Kka2,kka2_1:4,P00552,1.29095,NO,18,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.055,-3.59,1.535,,0.474,T,A,1.2,0.54,8.405,8.405,71.59,ABH,-1.821,0.168804,0.00724065,1.29095 kka2_1:2_Q27I,kka2_1:2_27,Kka2,kka2_1:2,P00552,1.29099,NO,27,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-1.659,-3.006,1.347,,0.608,.,A,0.64,0.71,0.521,,65.53,PPP,-1.90733,0.295029,0.00595365,1.29099 kka2_1:2_D238Q,kka2_1:2_238,Kka2,kka2_1:2,P00552,1.29106,NO,238,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.83,-2.348,-0.482,,0.604,H,A,0.75,-0.33,22.789,22.789,92.05,HAB,-2.633,0.295029,0.0113863,1.29106 beta-lactamase_0_M270C,beta-lactamase_0_270,TEM-1,beta-lactamase_0,P62593,1.2912,NO,270,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.723,,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.0500837,0.00767762,1.2912 kka2_1:4_P167L,kka2_1:4_167,Kka2,kka2_1:4,P00552,1.29124,NO,167,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-2.403,-2.565,0.162,,0.18,H,A,0.52,0.75,3.6,,64.39,HOH,-2.26633,0.168804,0.00543203,1.29124 kka2_1:2_A25R,kka2_1:2_25,Kka2,kka2_1:2,P00552,1.29126,NO,25,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.496,-2.407,-0.089,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.295029,0.00595636,1.29126 beta-lactamase_0_K190I,beta-lactamase_0_190,TEM-1,beta-lactamase_0,P62593,1.29128,NO,190,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-1.994,-3.984,1.99,,0.371,H,A,2.34,0.16,16.606,16.606,77.62,BBH,-1.64167,0.0500837,0.00574527,1.29128 kka2_1:2_E230S,kka2_1:2_230,Kka2,kka2_1:2,P00552,1.29142,NO,230,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.672,-2.395,-0.277,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.295029,0.00920051,1.29142 kka2_1:2_A79T,kka2_1:2_79,Kka2,kka2_1:2,P00552,1.29147,NO,79,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.368,-2.485,0.117,,0.563,.,B,0.46,-0.43,0.475,,71.59,HHH,-1.752,0.295029,0.00664821,1.29147 beta-lactamase_0_L135I,beta-lactamase_0_135,TEM-1,beta-lactamase_0,P62593,1.29148,NO,135,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.002,-2.037,1.035,,0.117,H,A,0.55,-0.58,0.705,,43.71,PHH,-1.03767,0.0500837,0.00244423,1.29148 kka2_1:2_P45R,kka2_1:2_45,Kka2,kka2_1:2,P00552,1.29152,NO,45,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.774,-3.184,1.41,,0.669,,B,0.52,-0.76,4.882,,71.59,BOH,-2.152,0.295029,0.00590481,1.29152 kka2_1:4_S114Q,kka2_1:4_114,Kka2,kka2_1:4,P00552,1.29152,NO,114,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.527,-3.268,0.741,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.168804,0.00705262,1.29152 kka2_1:4_Q219M,kka2_1:4_219,Kka2,kka2_1:4,P00552,1.29171,NO,219,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-0.93,-4.327,3.397,,0.088,H,A,0.64,-0.85,1.537,,50,HPA,-1.05167,0.168804,0.00237913,1.29171 kka2_1:2_M120L,kka2_1:2_120,Kka2,kka2_1:2,P00552,1.29187,NO,120,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-3.877,-0.807,-3.07,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.295029,0.00265808,1.29187 kka2_1:2_D62E,kka2_1:2_62,Kka2,kka2_1:2,P00552,1.29219,NO,62,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.591,-2.795,1.204,,0.262,H,A,0.75,0.08,10.048,10.048,64.39,PAA,-1.77833,0.295029,0.00744243,1.29219 kka2_1:8_D5M,kka2_1:8_5,Kka2,kka2_1:8,P00552,1.29223,NO,5,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.306,-4.66,3.354,,,,,,,1.147,,71.59,PAO,-1.784,0.100394,0.00222864,1.29223 kka2_1:8_D5M,kka2_1:8_5,Kka2,kka2_1:8,P00552,1.29223,NO,5,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.306,-4.66,3.354,,,,,,,1.147,,71.59,PAO,-1.784,0.100394,0.00222864,1.29223 kka2_1:4_H8R,kka2_1:4_8,Kka2,kka2_1:4,P00552,1.29233,NO,8,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-2.759,-3.714,0.955,,,,,,,,,71.59,HBH,-2.25467,0.168804,0.00256422,1.29233 kka2_1:4_G181T,kka2_1:4_181,Kka2,kka2_1:4,P00552,1.29242,NO,181,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-2.698,-2.358,-0.34,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.168804,0.00728319,1.29242 kka2_1:4_E96G,kka2_1:4_96,Kka2,kka2_1:4,P00552,1.29258,NO,96,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.573,-2.57,-0.003,,0.476,,B,1.52,-0.65,1.254,,71.59,OAH,-2.143,0.168804,0.00369441,1.29258 kka2_1:4_F133W,kka2_1:4_133,Kka2,kka2_1:4,P00552,1.29286,NO,133,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-0.871,-4.449,3.578,,0.178,.,B,0.58,0.43,0.786,,42.42,OHA,-0.871667,0.168804,0.00182168,1.29286 beta-lactamase_0_K190M,beta-lactamase_0_190,TEM-1,beta-lactamase_0,P62593,1.29303,NO,190,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.994,-4.714,2.72,,0.371,H,A,2.34,0.16,16.606,16.606,77.62,BBH,-1.64167,0.0500837,0.00574527,1.29303 kka2_1:8_V242W,kka2_1:8_242,Kka2,kka2_1:8,P00552,1.29314,NO,242,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-2.687,-5.598,2.911,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.100394,0.0102575,1.29314 kka2_1:8_V242W,kka2_1:8_242,Kka2,kka2_1:8,P00552,1.29314,NO,242,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-2.687,-5.598,2.911,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.100394,0.0102575,1.29314 kka2_1:4_G95S,kka2_1:4_95,Kka2,kka2_1:4,P00552,1.29317,NO,95,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-2.403,-1.66,-0.743,,0.126,E,B,0.29,-0.74,0.359,,71.59,HOA,-2.198,0.168804,0.00743616,1.29317 kka2_1:2_Q252N,kka2_1:2_252,Kka2,kka2_1:2,P00552,1.2932,NO,252,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.63,-3.762,1.132,,0.906,H,A,0.64,0.35,5.613,,92.05,PPB,-2.20733,0.295029,0.0121001,1.2932 kka2_1:4_V84H,kka2_1:4_84,Kka2,kka2_1:4,P00552,1.29323,NO,84,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-2.279,-3.484,1.205,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.168804,0.00724019,1.29323 kka2_1:8_E17H,kka2_1:8_17,Kka2,kka2_1:8,P00552,1.29337,NO,17,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.154,-3.247,1.093,,0.957,T,A,1.04,0.22,31.483,31.483,63.64,HAB,-2.432,0.100394,0.00688738,1.29337 kka2_1:8_E17H,kka2_1:8_17,Kka2,kka2_1:8,P00552,1.29337,NO,17,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.154,-3.247,1.093,,0.957,T,A,1.04,0.22,31.483,31.483,63.64,HAB,-2.432,0.100394,0.00688738,1.29337 kka2_1:8_V242F,kka2_1:8_242,Kka2,kka2_1:8,P00552,1.2936,NO,242,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-2.687,-4.427,1.74,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.100394,0.0102575,1.2936 kka2_1:8_V242F,kka2_1:8_242,Kka2,kka2_1:8,P00552,1.2936,NO,242,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-2.687,-4.427,1.74,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.100394,0.0102575,1.2936 kka2_1:4_A168M,kka2_1:4_168,Kka2,kka2_1:4,P00552,1.29363,NO,168,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.989,-4.833,2.844,,0.67,H,A,0.46,0.15,,,64.39,OHA,-2.12933,0.168804,0.00806773,1.29363 beta-lactamase_0_E87C,beta-lactamase_0_87,TEM-1,beta-lactamase_0,P62593,1.2938,NO,87,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.421,-5.162,3.741,,0.048,,B,1.04,0.92,1.159,,64.69,PAP,-1.969,0.0500837,0.00337888,1.2938 beta-lactamase_0_K232T,beta-lactamase_0_232,TEM-1,beta-lactamase_0,P62593,1.29388,NO,232,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-1.012,-3.464,2.452,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.0500837,0.00313441,1.29388 kka2_1:2_A79K,kka2_1:2_79,Kka2,kka2_1:2,P00552,1.29389,NO,79,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.368,-2.882,0.514,,0.563,.,B,0.46,-0.43,0.475,,71.59,HHH,-1.752,0.295029,0.00664821,1.29389 kka2_1:4_A13P,kka2_1:4_13,Kka2,kka2_1:4,P00552,1.29399,NO,13,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.248,-2.481,0.233,,0.689,G,A,0.46,0.99,,,92.05,OHH,-1.646,0.168804,0.00784241,1.29399 kka2_1:4_A13I,kka2_1:4_13,Kka2,kka2_1:4,P00552,1.29407,NO,13,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.248,-3.155,0.907,,0.689,G,A,0.46,0.99,,,92.05,OHH,-1.646,0.168804,0.00784241,1.29407 beta-lactamase_0_K190G,beta-lactamase_0_190,TEM-1,beta-lactamase_0,P62593,1.29418,NO,190,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.994,-3.44,1.446,,0.371,H,A,2.34,0.16,16.606,16.606,77.62,BBH,-1.64167,0.0500837,0.00574527,1.29418 kka2_1:4_G181N,kka2_1:4_181,Kka2,kka2_1:4,P00552,1.29429,NO,181,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-2.698,-3.022,0.324,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.168804,0.00728319,1.29429 beta-lactamase_0_M67F,beta-lactamase_0_67,TEM-1,beta-lactamase_0,P62593,1.29438,NO,67,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-2.231,-4.128,1.897,,0.006,G,P,0.55,-0.81,24.165,24.165,65.03,HHP,-1.502,0.0500837,0.00409753,1.29438 kka2_1:4_G6Y,kka2_1:4_6,Kka2,kka2_1:4,P00552,1.29454,NO,6,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.685,-4.17,2.485,,,,,,,,,71.59,AOH,-1.639,0.168804,0.00204693,1.29454 kka2_1:4_V46S,kka2_1:4_46,Kka2,kka2_1:4,P00552,1.29455,NO,46,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-2.62,-2.564,-0.056,,0.192,.,B,0.44,-1.12,9.564,,92.05,OHH,-1.88633,0.168804,0.00631301,1.29455 kka2_1:8_R239V,kka2_1:8_239,Kka2,kka2_1:8,P00552,1.29458,NO,239,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.949,-2.967,0.018,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.100394,0.00835326,1.29458 kka2_1:8_R239V,kka2_1:8_239,Kka2,kka2_1:8,P00552,1.29458,NO,239,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.949,-2.967,0.018,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.100394,0.00835326,1.29458 beta-lactamase_0_F228Q,beta-lactamase_0_228,TEM-1,beta-lactamase_0,P62593,1.2946,NO,228,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-2.342,-2.674,0.332,,0.154,E,B,0.58,-0.42,15.504,15.504,63.29,HHH,-1.53033,0.0500837,0.0046669,1.2946 kka2_1:8_A13P,kka2_1:8_13,Kka2,kka2_1:8,P00552,1.29462,NO,13,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.248,-2.481,0.233,,0.689,G,A,1.04,0.99,14.966,14.966,92.05,OHH,-1.646,0.100394,0.00784241,1.29462 kka2_1:8_A13P,kka2_1:8_13,Kka2,kka2_1:8,P00552,1.29462,NO,13,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.248,-2.481,0.233,,0.689,G,A,1.04,0.99,14.966,14.966,92.05,OHH,-1.646,0.100394,0.00784241,1.29462 kka2_1:4_A172D,kka2_1:4_172,Kka2,kka2_1:4,P00552,1.29464,NO,172,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.757,-2.549,0.792,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.168804,0.0079265,1.29464 kka2_1:4_L158F,kka2_1:4_158,Kka2,kka2_1:4,P00552,1.29466,NO,158,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.947,-1.154,-0.793,,0.095,,B,1.59,0.77,7.588,,63.64,AHA,-1.25333,0.168804,0.00529068,1.29466 kka2_1:4_E199M,kka2_1:4_199,Kka2,kka2_1:4,P00552,1.29469,NO,199,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.234,-4.802,2.568,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.168804,0.00854122,1.29469 kka2_1:8_Q4L,kka2_1:8_4,Kka2,kka2_1:8,P00552,1.29479,NO,4,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.361,-3.406,1.045,,,,,,,2.026,,71.59,APA,-1.95533,0.100394,0.00239179,1.29479 kka2_1:8_Q4L,kka2_1:8_4,Kka2,kka2_1:8,P00552,1.29479,NO,4,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.361,-3.406,1.045,,,,,,,2.026,,71.59,APA,-1.95533,0.100394,0.00239179,1.29479 kka2_1:8_V16G,kka2_1:8_16,Kka2,kka2_1:8,P00552,1.29479,NO,16,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-3.087,-2.751,-0.336,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.100394,0.00694011,1.29479 kka2_1:8_V16G,kka2_1:8_16,Kka2,kka2_1:8,P00552,1.29479,NO,16,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-3.087,-2.751,-0.336,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.100394,0.00694011,1.29479 beta-lactamase_0_F228Y,beta-lactamase_0_228,TEM-1,beta-lactamase_0,P62593,1.29486,NO,228,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-2.342,-4.005,1.663,,0.154,E,B,0.58,-0.42,15.504,15.504,63.29,HHH,-1.53033,0.0500837,0.0046669,1.29486 kka2_1:8_G6N,kka2_1:8_6,Kka2,kka2_1:8,P00552,1.2952,NO,6,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.685,-3.547,1.862,,,,,,,,,71.59,AOH,-1.639,0.100394,0.00204693,1.2952 kka2_1:8_G6N,kka2_1:8_6,Kka2,kka2_1:8,P00552,1.2952,NO,6,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.685,-3.547,1.862,,,,,,,,,71.59,AOH,-1.639,0.100394,0.00204693,1.2952 kka2_1:8_L243E,kka2_1:8_243,Kka2,kka2_1:8,P00552,1.29537,NO,243,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-2.651,-2.717,0.066,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.100394,0.00884927,1.29537 kka2_1:8_L243E,kka2_1:8_243,Kka2,kka2_1:8,P00552,1.29537,NO,243,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-2.651,-2.717,0.066,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.100394,0.00884927,1.29537 kka2_1:8_E161N,kka2_1:8_161,Kka2,kka2_1:8,P00552,1.29539,NO,161,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.581,-3.715,2.134,,0.829,G,A,1.04,2.24,11.923,11.923,92.05,AAB,-1.861,0.100394,0.00760103,1.29539 kka2_1:8_E161N,kka2_1:8_161,Kka2,kka2_1:8,P00552,1.29539,NO,161,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.581,-3.715,2.134,,0.829,G,A,1.04,2.24,11.923,11.923,92.05,AAB,-1.861,0.100394,0.00760103,1.29539 beta-lactamase_0_E61F,beta-lactamase_0_61,TEM-1,beta-lactamase_0,P62593,1.29548,NO,61,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.115,-4.422,2.307,,0.775,T,a,1.04,1.29,34.763,34.763,77.62,OAA,-1.92567,0.0500837,0.00440955,1.29548 kka2_1:4_V16F,kka2_1:4_16,Kka2,kka2_1:4,P00552,1.29557,NO,16,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-3.087,-4.39,1.303,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.168804,0.00694011,1.29557 kka2_1:2_P167M,kka2_1:2_167,Kka2,kka2_1:2,P00552,1.29565,NO,167,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-2.403,-4.574,2.171,,0.18,H,A,0.52,0.75,3.6,,64.39,HOH,-2.26633,0.295029,0.00543203,1.29565 kka2_1:8_A168K,kka2_1:8_168,Kka2,kka2_1:8,P00552,1.29569,NO,168,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.989,-2.846,0.857,,0.67,H,A,0.46,0.15,11.329,11.329,64.39,OHA,-2.12933,0.100394,0.00806773,1.29569 kka2_1:8_A168K,kka2_1:8_168,Kka2,kka2_1:8,P00552,1.29569,NO,168,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.989,-2.846,0.857,,0.67,H,A,0.46,0.15,11.329,11.329,64.39,OHA,-2.12933,0.100394,0.00806773,1.29569 beta-lactamase_0_G114M,beta-lactamase_0_114,TEM-1,beta-lactamase_0,P62593,1.2958,NO,114,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.094,-4.83,3.736,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.0500837,0.00224919,1.2958 kka2_1:2_A14P,kka2_1:2_14,Kka2,kka2_1:2,P00552,1.29581,NO,14,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.837,-3.126,1.289,,0.728,G,A,0.46,0.7,0.36,,71.59,HHH,-1.82567,0.295029,0.00706614,1.29581 kka2_1:8_A255Y,kka2_1:8_255,Kka2,kka2_1:8,P00552,1.29592,NO,255,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.715,-3.332,1.617,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.100394,0.0126809,1.29592 kka2_1:8_A255Y,kka2_1:8_255,Kka2,kka2_1:8,P00552,1.29592,NO,255,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.715,-3.332,1.617,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.100394,0.0126809,1.29592 kka2_1:2_L19I,kka2_1:2_19,Kka2,kka2_1:2,P00552,1.29599,NO,19,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.254,-2.338,1.084,,0.08,T,A,0.55,-0.26,17.165,17.165,65.53,BHH,-2.221,0.295029,0.00620703,1.29599 kka2_1:2_A172R,kka2_1:2_172,Kka2,kka2_1:2,P00552,1.29607,NO,172,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.757,-2.665,0.908,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.295029,0.0079265,1.29607 kka2_1:4_Q26M,kka2_1:4_26,Kka2,kka2_1:4,P00552,1.29614,NO,26,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.18,-3.49,1.31,,0.448,E,B,0.4,0.44,5.022,,92.05,HPP,-2.11167,0.168804,0.00708962,1.29614 beta-lactamase_0_G236N,beta-lactamase_0_236,TEM-1,beta-lactamase_0,P62593,1.29677,NO,236,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.784,-3.509,2.725,,0.241,,b,0.29,-0.59,3.506,,64.69,HOO,-1.025,0.0500837,0.00162372,1.29677 kka2_1:4_A137F,kka2_1:4_137,Kka2,kka2_1:4,P00552,1.29685,NO,137,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.156,-3.905,1.749,,0.029,H,A,0.46,0.34,2.227,,63.26,PHB,-2.559,0.168804,0.00515054,1.29685 kka2_1:8_P45N,kka2_1:8_45,Kka2,kka2_1:8,P00552,1.29686,NO,45,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.774,-3.854,2.08,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.100394,0.00590481,1.29686 kka2_1:8_P45N,kka2_1:8_45,Kka2,kka2_1:8,P00552,1.29686,NO,45,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.774,-3.854,2.08,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.100394,0.00590481,1.29686 kka2_1:4_S40N,kka2_1:4_40,Kka2,kka2_1:4,P00552,1.2969,NO,40,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.645,-3.752,1.107,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.168804,0.00693477,1.2969 kka2_1:8_A79K,kka2_1:8_79,Kka2,kka2_1:8,P00552,1.29696,NO,79,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.368,-2.882,0.514,,0.563,.,B,0.46,-0.43,,,71.59,HHH,-1.752,0.100394,0.00664821,1.29696 kka2_1:8_A79K,kka2_1:8_79,Kka2,kka2_1:8,P00552,1.29696,NO,79,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.368,-2.882,0.514,,0.563,.,B,0.46,-0.43,,,71.59,HHH,-1.752,0.100394,0.00664821,1.29696 kka2_1:8_R18F,kka2_1:8_18,Kka2,kka2_1:8,P00552,1.29699,NO,18,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.055,-3.418,1.363,,0.474,T,A,1.2,0.54,19.629,19.629,71.59,ABH,-1.821,0.100394,0.00724065,1.29699 kka2_1:8_R18F,kka2_1:8_18,Kka2,kka2_1:8,P00552,1.29699,NO,18,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.055,-3.418,1.363,,0.474,T,A,1.2,0.54,19.629,19.629,71.59,ABH,-1.821,0.100394,0.00724065,1.29699 beta-lactamase_0_E272I,beta-lactamase_0_272,TEM-1,beta-lactamase_0,P62593,1.29706,NO,272,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.0500837,0.00545371,1.29706 beta-lactamase_0_K232M,beta-lactamase_0_232,TEM-1,beta-lactamase_0,P62593,1.29707,NO,232,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.012,-4.522,3.51,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.0500837,0.00313441,1.29707 beta-lactamase_0_E102D,beta-lactamase_0_102,TEM-1,beta-lactamase_0,P62593,1.29716,NO,102,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.118,-2.118,0,,0.722,S,B,1.04,1.82,4.773,,73.08,HAH,-1.581,0.0500837,0.00486633,1.29716 kka2_1:4_A56Q,kka2_1:4_56,Kka2,kka2_1:4,P00552,1.29742,NO,56,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.083,-4.08,1.997,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.168804,0.00717715,1.29742 kka2_1:8_I254M,kka2_1:8_254,Kka2,kka2_1:8,P00552,1.29754,NO,254,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.933,-2.224,0.291,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.100394,0.0132375,1.29754 kka2_1:8_I254M,kka2_1:8_254,Kka2,kka2_1:8,P00552,1.29754,NO,254,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.933,-2.224,0.291,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.100394,0.0132375,1.29754 kka2_1:4_L53S,kka2_1:4_53,Kka2,kka2_1:4,P00552,1.29771,NO,53,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-2.681,-2.891,0.21,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.168804,0.00671168,1.29771 kka2_1:4_Q27M,kka2_1:4_27,Kka2,kka2_1:4,P00552,1.29783,NO,27,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-1.659,-3.318,1.659,,0.608,,A,0.4,0.71,1.498,,65.53,PPP,-1.90733,0.168804,0.00595365,1.29783 kka2_1:4_R173T,kka2_1:4_173,Kka2,kka2_1:4,P00552,1.29784,NO,173,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.407,-3.026,0.619,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.168804,0.00784999,1.29784 kka2_1:4_T225F,kka2_1:4_225,Kka2,kka2_1:4,P00552,1.29788,NO,225,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.393,-4.221,1.828,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.168804,0.0113598,1.29788 kka2_1:8_T225C,kka2_1:8_225,Kka2,kka2_1:8,P00552,1.2979,NO,225,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.393,-1.895,-0.498,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.100394,0.0113598,1.2979 kka2_1:8_T225C,kka2_1:8_225,Kka2,kka2_1:8,P00552,1.2979,NO,225,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.393,-1.895,-0.498,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.100394,0.0113598,1.2979 kka2_1:8_V242E,kka2_1:8_242,Kka2,kka2_1:8,P00552,1.29802,NO,242,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-2.687,-2.323,-0.364,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.100394,0.0102575,1.29802 kka2_1:8_V242E,kka2_1:8_242,Kka2,kka2_1:8,P00552,1.29802,NO,242,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-2.687,-2.323,-0.364,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.100394,0.0102575,1.29802 kka2_1:4_E199R,kka2_1:4_199,Kka2,kka2_1:4,P00552,1.29805,NO,199,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.234,-3.022,0.788,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.168804,0.00854122,1.29805 kka2_1:4_G6S,kka2_1:4_6,Kka2,kka2_1:4,P00552,1.29807,NO,6,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.685,-3.143,1.458,,,,,,,,,71.59,AOH,-1.639,0.168804,0.00204693,1.29807 kka2_1:4_D23V,kka2_1:4_23,Kka2,kka2_1:4,P00552,1.29812,NO,23,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.459,-2.803,0.344,,0.695,E,B,0.75,-0.65,2.416,,65.53,HAH,-1.94033,0.168804,0.007195,1.29812 kka2_1:2_A248W,kka2_1:2_248,Kka2,kka2_1:2,P00552,1.29825,NO,248,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.124,-5.601,3.477,,0.825,S,b,0.46,0.46,,,92.05,HHO,-2.15,0.295029,0.0125484,1.29825 kka2_1:4_P45R,kka2_1:4_45,Kka2,kka2_1:4,P00552,1.29826,NO,45,P,R,PR,Special,PositiveCharge,6.3,6.34148,0.0414782,103,115,174,59,112.7,173.4,60.7,-1.774,-3.184,1.41,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.168804,0.00590481,1.29826 kka2_1:2_E149R,kka2_1:2_149,Kka2,kka2_1:2,P00552,1.29831,NO,149,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.994,-2.471,0.477,,0.674,H,A,1.04,1.63,15.361,15.361,71.59,HAH,-1.59667,0.295029,0.00803343,1.29831 kka2_1:4_A110H,kka2_1:4_110,Kka2,kka2_1:4,P00552,1.29833,NO,110,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.064,-3.65,1.586,,0.175,H,A,0.46,-1.19,23.237,23.237,71.59,OHA,-1.91867,0.168804,0.00759851,1.29833 kka2_1:2_D180N,kka2_1:2_180,Kka2,kka2_1:2,P00552,1.29843,NO,180,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.416,-3.09,0.674,,1.03,S,a,0.75,1.5,1.27,,71.59,OAO,-2.02933,0.295029,0.00756412,1.29843 kka2_1:4_Q4W,kka2_1:4_4,Kka2,kka2_1:4,P00552,1.29844,NO,4,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.361,-5.167,2.806,,,,,,,2.026,,71.59,APA,-1.95533,0.168804,0.00239179,1.29844 kka2_1:4_P167I,kka2_1:4_167,Kka2,kka2_1:4,P00552,1.29857,NO,167,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-2.403,-2.742,0.339,,0.18,H,A,0.52,0.75,3.6,,64.39,HOH,-2.26633,0.168804,0.00543203,1.29857 kka2_1:2_V242D,kka2_1:2_242,Kka2,kka2_1:2,P00552,1.29866,NO,242,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-2.687,-2.207,-0.48,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.295029,0.0102575,1.29866 beta-lactamase_0_V157C,beta-lactamase_0_157,TEM-1,beta-lactamase_0,P62593,1.29876,NO,157,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.751,-4.91,3.159,,0.308,S,a,0.44,-0.75,3.106,,69.58,BHP,-2.00767,0.0500837,0.00506849,1.29876 kka2_1:8_T146S,kka2_1:8_146,Kka2,kka2_1:8,P00552,1.29878,NO,146,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.978,-2.727,-0.251,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.100394,0.00606474,1.29878 kka2_1:8_T146S,kka2_1:8_146,Kka2,kka2_1:8,P00552,1.29878,NO,146,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.978,-2.727,-0.251,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.100394,0.00606474,1.29878 kka2_1:4_A247D,kka2_1:4_247,Kka2,kka2_1:4,P00552,1.29884,NO,247,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.459,-3.029,0.57,,1.01,S,A,0.46,0.65,,,92.05,HHH,-2.197,0.168804,0.0102428,1.29884 kka2_1:2_Q4W,kka2_1:2_4,Kka2,kka2_1:2,P00552,1.29887,NO,4,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.361,-5.167,2.806,,,,,,,2.026,,71.59,APA,-1.95533,0.295029,0.00239179,1.29887 kka2_1:4_Q155N,kka2_1:4_155,Kka2,kka2_1:4,P00552,1.29896,NO,155,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.606,-3.65,1.044,,0.525,T,A,0.64,1.49,1.592,,63.64,APA,-1.726,0.168804,0.00641853,1.29896 kka2_1:4_T225Y,kka2_1:4_225,Kka2,kka2_1:4,P00552,1.29906,NO,225,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.393,-4.28,1.887,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.168804,0.0113598,1.29906 kka2_1:4_L19F,kka2_1:4_19,Kka2,kka2_1:4,P00552,1.29907,NO,19,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.254,-2.137,0.883,,0.08,T,A,1.59,-0.26,2.645,,65.53,BHH,-2.221,0.168804,0.00620703,1.29907 kka2_1:4_A65K,kka2_1:4_65,Kka2,kka2_1:4,P00552,1.29916,NO,65,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.744,-3.037,1.293,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.168804,0.00709258,1.29916 kka2_1:2_Q163C,kka2_1:2_163,Kka2,kka2_1:2,P00552,1.29918,NO,163,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.162,-5.049,2.887,,0.58,T,B,0.64,1.85,3.888,,64.02,BPO,-1.78333,0.295029,0.00719507,1.29918 kka2_1:2_A166Q,kka2_1:2_166,Kka2,kka2_1:2,P00552,1.29938,NO,166,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.407,-3.207,0.8,,0.534,.,B,0.46,1.03,23.175,23.175,71.59,HHO,-2.421,0.295029,0.00799912,1.29938 kka2_1:8_P167L,kka2_1:8_167,Kka2,kka2_1:8,P00552,1.29948,NO,167,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-2.403,-2.565,0.162,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.100394,0.00543203,1.29948 kka2_1:8_P167L,kka2_1:8_167,Kka2,kka2_1:8,P00552,1.29948,NO,167,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-2.403,-2.565,0.162,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.100394,0.00543203,1.29948 kka2_1:4_I2R,kka2_1:4_2,Kka2,kka2_1:4,P00552,1.29957,NO,2,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.787,-3.848,2.061,,,,,,,,,71.59,HHA,-1.92433,0.168804,0.00246644,1.29957 kka2_1:2_G6L,kka2_1:2_6,Kka2,kka2_1:2,P00552,1.29961,NO,6,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.685,-3.363,1.678,,,,,,,,,71.59,AOH,-1.639,0.295029,0.00204693,1.29961 kka2_1:2_A248E,kka2_1:2_248,Kka2,kka2_1:2,P00552,1.29997,NO,248,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.124,-2.197,0.073,,0.825,S,b,0.46,0.46,,,92.05,HHO,-2.15,0.295029,0.0125484,1.29997 kka2_1:8_A13Q,kka2_1:8_13,Kka2,kka2_1:8,P00552,1.29998,NO,13,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.248,-3.029,0.781,,0.689,G,A,1.04,0.99,14.966,14.966,92.05,OHH,-1.646,0.100394,0.00784241,1.29998 kka2_1:8_A13Q,kka2_1:8_13,Kka2,kka2_1:8,P00552,1.29998,NO,13,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.248,-3.029,0.781,,0.689,G,A,1.04,0.99,14.966,14.966,92.05,OHH,-1.646,0.100394,0.00784241,1.29998 kka2_1:2_E149K,kka2_1:2_149,Kka2,kka2_1:2,P00552,1.30001,NO,149,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-1.994,-2.785,0.791,,0.674,H,A,1.04,1.63,15.361,15.361,71.59,HAH,-1.59667,0.295029,0.00803343,1.30001 kka2_1:2_S251D,kka2_1:2_251,Kka2,kka2_1:2,P00552,1.30004,NO,251,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.636,-2.837,0.201,,0.712,H,A,0.27,-0.25,32.832,32.832,71.59,APP,-2.09367,0.295029,0.0138916,1.30004 kka2_1:8_G6T,kka2_1:8_6,Kka2,kka2_1:8,P00552,1.3001,NO,6,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.685,-3.379,1.694,,,,,,,,,71.59,AOH,-1.639,0.100394,0.00204693,1.3001 kka2_1:8_G6T,kka2_1:8_6,Kka2,kka2_1:8,P00552,1.3001,NO,6,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.685,-3.379,1.694,,,,,,,,,71.59,AOH,-1.639,0.100394,0.00204693,1.3001 kka2_1:8_D250C,kka2_1:8_250,Kka2,kka2_1:8,P00552,1.3002,NO,250,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.015,-5.204,4.189,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.100394,0.0177103,1.3002 kka2_1:8_D250C,kka2_1:8_250,Kka2,kka2_1:8,P00552,1.3002,NO,250,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.015,-5.204,4.189,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.100394,0.0177103,1.3002 kka2_1:2_V242N,kka2_1:2_242,Kka2,kka2_1:2,P00552,1.30028,NO,242,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-2.687,-3.122,0.435,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.295029,0.0102575,1.30028 kka2_1:8_G234T,kka2_1:8_234,Kka2,kka2_1:8,P00552,1.30046,NO,234,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-2.9,-3.606,0.706,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.100394,0.00984449,1.30046 kka2_1:8_G234T,kka2_1:8_234,Kka2,kka2_1:8,P00552,1.30046,NO,234,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-2.9,-3.606,0.706,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.100394,0.00984449,1.30046 kka2_1:4_A108D,kka2_1:4_108,Kka2,kka2_1:4,P00552,1.30055,NO,108,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.061,-2.378,0.317,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.168804,0.00751209,1.30055 kka2_1:8_L165T,kka2_1:8_165,Kka2,kka2_1:8,P00552,1.30067,NO,165,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-2.453,-3.066,0.613,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.100394,0.00801161,1.30067 kka2_1:8_L165T,kka2_1:8_165,Kka2,kka2_1:8,P00552,1.30067,NO,165,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-2.453,-3.066,0.613,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.100394,0.00801161,1.30067 kka2_1:2_T125A,kka2_1:2_125,Kka2,kka2_1:2,P00552,1.30086,NO,125,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.622,-1.886,-0.736,,0.791,T,A,0.22,0.33,2.029,,92.05,BPH,-1.56933,0.295029,0.00821755,1.30086 kka2_1:8_Q252N,kka2_1:8_252,Kka2,kka2_1:8,P00552,1.30089,NO,252,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.63,-3.762,1.132,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.100394,0.0121001,1.30089 kka2_1:8_Q252N,kka2_1:8_252,Kka2,kka2_1:8,P00552,1.30089,NO,252,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.63,-3.762,1.132,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.100394,0.0121001,1.30089 kka2_1:4_Q155A,kka2_1:4_155,Kka2,kka2_1:4,P00552,1.30098,NO,155,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.606,-2.225,-0.381,,0.525,T,A,0.64,1.49,1.592,,63.64,APA,-1.726,0.168804,0.00641853,1.30098 kka2_1:2_S40Y,kka2_1:2_40,Kka2,kka2_1:2,P00552,1.30121,NO,40,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.645,-4.369,1.724,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.295029,0.00693477,1.30121 kka2_1:4_D156F,kka2_1:4_156,Kka2,kka2_1:4,P00552,1.30143,NO,156,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.696,-4.395,2.699,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.168804,0.00926998,1.30143 beta-lactamase_0_T116Q,beta-lactamase_0_116,TEM-1,beta-lactamase_0,P62593,1.30146,NO,116,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.28,-3.898,2.618,,0.115,E,B,0.22,-0.12,1.356,,67.48,HPH,-1.39967,0.0500837,0.00336175,1.30146 kka2_1:4_E3P,kka2_1:4_3,Kka2,kka2_1:4,P00552,1.30156,NO,3,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.199,-3.691,1.492,,,,,,,7.22,,92.05,HAP,-2.11567,0.168804,0.00267607,1.30156 kka2_1:2_Q136R,kka2_1:2_136,Kka2,kka2_1:2,P00552,1.30176,NO,136,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-3.021,-1.428,-1.593,,0.331,,b,0.4,0.96,2.726,,92.05,BPH,-2.16933,0.295029,0.00624149,1.30176 kka2_1:2_I2F,kka2_1:2_2,Kka2,kka2_1:2,P00552,1.30188,NO,2,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.787,-3.633,1.846,,,,,,,5.773,,71.59,HHA,-1.92433,0.295029,0.00246644,1.30188 kka2_1:4_S114F,kka2_1:4_114,Kka2,kka2_1:4,P00552,1.302,NO,114,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.527,-4.392,1.865,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.168804,0.00705262,1.302 kka2_1:2_A56E,kka2_1:2_56,Kka2,kka2_1:2,P00552,1.30208,NO,56,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-2.083,-2.646,0.563,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.295029,0.00717715,1.30208 kka2_1:2_A79N,kka2_1:2_79,Kka2,kka2_1:2,P00552,1.30224,NO,79,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.368,-3.84,1.472,,0.563,.,B,0.46,-0.43,0.475,,71.59,HHH,-1.752,0.295029,0.00664821,1.30224 kka2_1:2_C31L,kka2_1:2_31,Kka2,kka2_1:2,P00552,1.30232,NO,31,C,L,CL,Special,Hydrophobic,5.07,9.7088,4.6388,198,121,131,10,108.5,166.7,58.2,-2.246,-3.487,1.241,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.295029,0.00681582,1.30232 kka2_1:4_M178W,kka2_1:4_178,Kka2,kka2_1:4,P00552,1.30241,NO,178,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-3.206,-5.507,2.301,,0.554,.,b,0.55,0.68,9.913,9.913,71.59,BHO,-2.154,0.168804,0.00717253,1.30241 kka2_1:8_S40K,kka2_1:8_40,Kka2,kka2_1:8,P00552,1.30252,NO,40,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.645,-2.814,0.169,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.100394,0.00693477,1.30252 kka2_1:8_S40K,kka2_1:8_40,Kka2,kka2_1:8,P00552,1.30252,NO,40,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.645,-2.814,0.169,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.100394,0.00693477,1.30252 kka2_1:2_T146A,kka2_1:2_146,Kka2,kka2_1:2,P00552,1.30279,NO,146,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.978,-1.627,-1.351,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.295029,0.00606474,1.30279 kka2_1:2_L81K,kka2_1:2_81,Kka2,kka2_1:2,P00552,1.30283,NO,81,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.427,-3.851,2.424,,0.46,E,A,1.59,-0.14,1.895,,63.64,HHA,-1.50567,0.295029,0.00805839,1.30283 kka2_1:4_Q163I,kka2_1:4_163,Kka2,kka2_1:4,P00552,1.30284,NO,163,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.162,-3.594,1.432,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.168804,0.00719507,1.30284 beta-lactamase_0_R118A,beta-lactamase_0_118,TEM-1,beta-lactamase_0,P62593,1.30305,NO,118,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.413,-1.798,-0.615,,0.457,H,A,1.2,1.39,3.961,,77.62,HBA,-1.785,0.0500837,0.00538794,1.30305 kka2_1:2_S251Y,kka2_1:2_251,Kka2,kka2_1:2,P00552,1.3032,NO,251,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.636,-4.395,1.759,,0.712,H,A,0.27,-0.25,32.832,32.832,71.59,APP,-2.09367,0.295029,0.0138916,1.3032 kka2_1:4_S11P,kka2_1:4_11,Kka2,kka2_1:4,P00552,1.30342,NO,11,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.322,-2.34,0.018,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.168804,0.00381691,1.30342 kka2_1:4_V46D,kka2_1:4_46,Kka2,kka2_1:4,P00552,1.30345,NO,46,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-2.62,-2.475,-0.145,,0.192,.,B,0.44,-1.12,9.564,,92.05,OHH,-1.88633,0.168804,0.00631301,1.30345 kka2_1:4_S11W,kka2_1:4_11,Kka2,kka2_1:4,P00552,1.30364,NO,11,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.322,-5.275,2.953,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.168804,0.00381691,1.30364 kka2_1:4_S54C,kka2_1:4_54,Kka2,kka2_1:4,P00552,1.30367,NO,54,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.471,-4.966,2.495,,0.408,S,b,0.27,1.01,17.332,17.332,71.59,HPO,-2.259,0.168804,0.00782867,1.30367 kka2_1:4_A168T,kka2_1:4_168,Kka2,kka2_1:4,P00552,1.30371,NO,168,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.989,-2.711,0.722,,0.67,H,A,0.46,0.15,,,64.39,OHA,-2.12933,0.168804,0.00806773,1.30371 kka2_1:4_Q155V,kka2_1:4_155,Kka2,kka2_1:4,P00552,1.30371,NO,155,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.606,-2.82,0.214,,0.525,T,A,0.64,1.49,1.592,,63.64,APA,-1.726,0.168804,0.00641853,1.30371 beta-lactamase_0_P255F,beta-lactamase_0_255,TEM-1,beta-lactamase_0,P62593,1.30374,NO,255,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-2.266,,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.0500837,0.00499612,1.30374 kka2_1:8_D5S,kka2_1:8_5,Kka2,kka2_1:8,P00552,1.3038,NO,5,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.306,-2.972,1.666,,,,,,,1.147,,71.59,PAO,-1.784,0.100394,0.00222864,1.3038 kka2_1:8_D5S,kka2_1:8_5,Kka2,kka2_1:8,P00552,1.3038,NO,5,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.306,-2.972,1.666,,,,,,,1.147,,71.59,PAO,-1.784,0.100394,0.00222864,1.3038 kka2_1:8_A247T,kka2_1:8_247,Kka2,kka2_1:8,P00552,1.30384,NO,247,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.459,-2.783,0.324,,1.01,S,A,0.46,0.65,18.904,18.904,92.05,HHH,-2.197,0.100394,0.0102428,1.30384 kka2_1:8_A247T,kka2_1:8_247,Kka2,kka2_1:8,P00552,1.30384,NO,247,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.459,-2.783,0.324,,1.01,S,A,0.46,0.65,18.904,18.904,92.05,HHH,-2.197,0.100394,0.0102428,1.30384 kka2_1:8_Q26V,kka2_1:8_26,Kka2,kka2_1:8,P00552,1.30384,NO,26,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.18,-3.715,1.535,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.100394,0.00708962,1.30384 kka2_1:8_Q26V,kka2_1:8_26,Kka2,kka2_1:8,P00552,1.30384,NO,26,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.18,-3.715,1.535,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.100394,0.00708962,1.30384 kka2_1:8_G6K,kka2_1:8_6,Kka2,kka2_1:8,P00552,1.30386,NO,6,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.685,-2.23,0.545,,,,,,,,,71.59,AOH,-1.639,0.100394,0.00204693,1.30386 kka2_1:8_G6K,kka2_1:8_6,Kka2,kka2_1:8,P00552,1.30386,NO,6,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.685,-2.23,0.545,,,,,,,,,71.59,AOH,-1.639,0.100394,0.00204693,1.30386 beta-lactamase_0_E62W,beta-lactamase_0_62,TEM-1,beta-lactamase_0,P62593,1.30419,NO,62,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.193,-5.409,4.216,,0.342,S,B,1.04,-0.3,5.784,,73.08,AAB,-1.417,0.0500837,0.00264802,1.30419 kka2_1:2_D238A,kka2_1:2_238,Kka2,kka2_1:2,P00552,1.30463,NO,238,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.83,-1.842,-0.988,,0.604,H,A,0.75,-0.33,22.789,22.789,92.05,HAB,-2.633,0.295029,0.0113863,1.30463 kka2_1:4_G55T,kka2_1:4_55,Kka2,kka2_1:4,P00552,1.30471,NO,55,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.625,-3.642,2.017,,0.517,S,b,0.75,1.19,15.753,15.753,63.64,POH,-2.05967,0.168804,0.00667877,1.30471 beta-lactamase_0_F58H,beta-lactamase_0_58,TEM-1,beta-lactamase_0,P62593,1.30479,NO,58,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-2.914,-2.092,-0.822,,0.266,E,B,0.58,-0.07,24.637,24.637,77.62,PHB,-2.059,0.0500837,0.00523369,1.30479 kka2_1:8_D23Q,kka2_1:8_23,Kka2,kka2_1:8,P00552,1.30493,NO,23,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.459,-3.078,0.619,,0.695,E,B,0.75,-0.65,,,65.53,HAH,-1.94033,0.100394,0.007195,1.30493 kka2_1:8_D23Q,kka2_1:8_23,Kka2,kka2_1:8,P00552,1.30493,NO,23,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.459,-3.078,0.619,,0.695,E,B,0.75,-0.65,,,65.53,HAH,-1.94033,0.100394,0.007195,1.30493 kka2_1:2_H8W,kka2_1:2_8,Kka2,kka2_1:2,P00552,1.30495,NO,8,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-2.759,-5.188,2.429,,,,,,,,,71.59,HBH,-2.25467,0.295029,0.00256422,1.30495 kka2_1:4_R122Q,kka2_1:4_122,Kka2,kka2_1:4,P00552,1.30495,NO,122,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.175,-2.893,0.718,,0.487,H,A,0.16,0.26,16.436,16.436,71.59,BBH,-1.53833,0.168804,0.00736512,1.30495 kka2_1:4_E17D,kka2_1:4_17,Kka2,kka2_1:4,P00552,1.30496,NO,17,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.154,-2.384,0.23,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.168804,0.00688738,1.30496 kka2_1:2_Q61D,kka2_1:2_61,Kka2,kka2_1:2,P00552,1.30502,NO,61,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.982,-3.015,0.033,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.295029,0.00612092,1.30502 kka2_1:8_I2N,kka2_1:8_2,Kka2,kka2_1:8,P00552,1.30508,NO,2,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.787,-3.72,1.933,,,,,,,,,71.59,HHA,-1.92433,0.100394,0.00246644,1.30508 kka2_1:8_I2N,kka2_1:8_2,Kka2,kka2_1:8,P00552,1.30508,NO,2,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.787,-3.72,1.933,,,,,,,,,71.59,HHA,-1.92433,0.100394,0.00246644,1.30508 beta-lactamase_0_V106R,beta-lactamase_0_106,TEM-1,beta-lactamase_0,P62593,1.30514,NO,106,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.218,-4.201,2.983,,0.258,T,A,0.44,0.24,0.952,,72.73,OHP,-1.04933,0.0500837,0.00304168,1.30514 kka2_1:4_C192T,kka2_1:4_192,Kka2,kka2_1:4,P00552,1.30521,NO,192,C,T,CT,Special,Polar,5.07,5.6,0.53,149,121,119,-2,108.5,116.1,7.6,-1.067,-2.666,1.599,,0.095,.,B,0.46,-0.75,1.333,,50,HOH,-0.960333,0.168804,0.00485428,1.30521 kka2_1:2_A13M,kka2_1:2_13,Kka2,kka2_1:2,P00552,1.30525,NO,13,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.248,-3.735,1.487,,0.689,G,A,0.46,0.99,,,92.05,OHH,-1.646,0.295029,0.00784241,1.30525 kka2_1:2_M1I,kka2_1:2_1,Kka2,kka2_1:2,P00552,1.30533,NO,1,M,I,MI,Hydrophobic,Hydrophobic,5.74,6.02,0.28,10,149,131,-18,162.9,166.7,3.8,-1.787,-2.748,0.961,,,,,,,1.347,,62.12,NAHH,-1.787,0.295029,0.00251939,1.30533 kka2_1:4_T225W,kka2_1:4_225,Kka2,kka2_1:4,P00552,1.30534,NO,225,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.393,-5.412,3.019,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.168804,0.0113598,1.30534 kka2_1:2_L103A,kka2_1:2_103,Kka2,kka2_1:2,P00552,1.30551,NO,103,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-2.362,-1.403,-0.959,,0.394,T,A,0.55,-0.99,3.499,,63.64,HHP,-1.534,0.295029,0.00574792,1.30551 beta-lactamase_0_R239K,beta-lactamase_0_239,TEM-1,beta-lactamase_0,P62593,1.30559,NO,239,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.0500837,0.00213852,1.30559 kka2_1:2_G181Y,kka2_1:2_181,Kka2,kka2_1:2,P00552,1.30571,NO,181,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-2.698,-3.473,0.775,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.295029,0.00728319,1.30571 kka2_1:2_G151N,kka2_1:2_151,Kka2,kka2_1:2,P00552,1.30592,NO,151,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.873,-2.707,1.834,,0.678,T,l,0.29,1.36,1.357,,49.62,HOH,-1.11433,0.295029,0.00339918,1.30592 kka2_1:2_L47F,kka2_1:2_47,Kka2,kka2_1:2,P00552,1.30602,NO,47,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.265,-2.523,1.258,,0.139,E,B,0.55,-0.86,2.369,,63.26,HHH,-1.77933,0.295029,0.00509386,1.30602 kka2_1:2_R173L,kka2_1:2_173,Kka2,kka2_1:2,P00552,1.30603,NO,173,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.407,-2.806,0.399,,0.308,H,A,0.16,-0.13,15.389,15.389,65.53,HBH,-1.70533,0.295029,0.00784999,1.30603 kka2_1:8_Q252W,kka2_1:8_252,Kka2,kka2_1:8,P00552,1.30607,NO,252,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.63,-5.559,2.929,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.100394,0.0121001,1.30607 kka2_1:8_Q252W,kka2_1:8_252,Kka2,kka2_1:8,P00552,1.30607,NO,252,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.63,-5.559,2.929,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.100394,0.0121001,1.30607 kka2_1:4_A79H,kka2_1:4_79,Kka2,kka2_1:4,P00552,1.30609,NO,79,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.368,-3.321,0.953,,0.563,.,B,0.46,-0.43,2.291,,71.59,HHH,-1.752,0.168804,0.00664821,1.30609 kka2_1:4_A14D,kka2_1:4_14,Kka2,kka2_1:4,P00552,1.30613,NO,14,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.837,-2.812,0.975,,0.728,G,A,0.46,0.7,0.36,,71.59,HHH,-1.82567,0.168804,0.00706614,1.30613 kka2_1:4_D238S,kka2_1:4_238,Kka2,kka2_1:4,P00552,1.30628,NO,238,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.83,-2.933,0.103,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.168804,0.0113863,1.30628 kka2_1:4_L165Q,kka2_1:4_165,Kka2,kka2_1:4,P00552,1.30668,NO,165,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-2.453,-2.33,-0.123,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.168804,0.00801161,1.30668 beta-lactamase_0_I140M,beta-lactamase_0_140,TEM-1,beta-lactamase_0,P62593,1.30685,NO,140,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.733,-4.137,2.404,,0.128,H,A,0.48,0.41,4.714,,73.08,PHO,-1.48733,0.0500837,0.00597777,1.30685 beta-lactamase_0_A230W,beta-lactamase_0_230,TEM-1,beta-lactamase_0,P62593,1.30687,NO,230,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.154,-5.319,4.165,,0.01,E,B,0.46,-1.17,2.179,,50,HHA,-1.079,0.0500837,0.00516841,1.30687 kka2_1:4_A172M,kka2_1:4_172,Kka2,kka2_1:4,P00552,1.30704,NO,172,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.757,-4.761,3.004,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.168804,0.0079265,1.30704 kka2_1:2_A9G,kka2_1:2_9,Kka2,kka2_1:2,P00552,1.30706,NO,9,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.079,-3.28,1.201,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.295029,0.00273264,1.30706 kka2_1:2_Q155E,kka2_1:2_155,Kka2,kka2_1:2,P00552,1.30729,NO,155,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.606,-1.223,-1.383,,0.525,T,A,0.64,1.49,1.592,,63.64,APA,-1.726,0.295029,0.00641853,1.30729 kka2_1:2_S40K,kka2_1:2_40,Kka2,kka2_1:2,P00552,1.30747,NO,40,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.645,-2.814,0.169,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.295029,0.00693477,1.30747 kka2_1:2_I2N,kka2_1:2_2,Kka2,kka2_1:2,P00552,1.30748,NO,2,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.787,-3.72,1.933,,,,,,,5.773,,71.59,HHA,-1.92433,0.295029,0.00246644,1.30748 kka2_1:4_Q136G,kka2_1:4_136,Kka2,kka2_1:4,P00552,1.30768,NO,136,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-3.021,-2.521,-0.5,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.168804,0.00624149,1.30768 kka2_1:2_V75I,kka2_1:2_75,Kka2,kka2_1:2,P00552,1.30776,NO,75,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-2.06,-1.939,-0.121,,0.042,.,B,0.44,-0.2,2.815,,71.59,OHO,-1.563,0.295029,0.00693733,1.30776 kka2_1:4_P76K,kka2_1:4_76,Kka2,kka2_1:4,P00552,1.30776,NO,76,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.449,-3.635,2.186,,0.331,,B,0.52,-0.41,7.463,,63.64,HOO,-1.662,0.168804,0.00625685,1.30776 kka2_1:8_D23F,kka2_1:8_23,Kka2,kka2_1:8,P00552,1.30784,NO,23,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.459,-4.448,1.989,,0.695,E,B,0.75,-0.65,,,65.53,HAH,-1.94033,0.100394,0.007195,1.30784 kka2_1:8_D23F,kka2_1:8_23,Kka2,kka2_1:8,P00552,1.30784,NO,23,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.459,-4.448,1.989,,0.695,E,B,0.75,-0.65,,,65.53,HAH,-1.94033,0.100394,0.007195,1.30784 kka2_1:4_T146S,kka2_1:4_146,Kka2,kka2_1:4,P00552,1.30806,NO,146,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.978,-2.727,-0.251,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.168804,0.00606474,1.30806 beta-lactamase_0_C121T,beta-lactamase_0_121,TEM-1,beta-lactamase_0,P62593,1.30808,NO,121,C,T,CT,Special,Polar,5.07,5.6,0.53,149,121,119,-2,108.5,116.1,7.6,-0.953,-3.447,2.494,,,H,A,0.46,-0.81,3.302,,63.29,HOP,-1.46767,0.0500837,0.000744322,1.30808 kka2_1:4_E199Y,kka2_1:4_199,Kka2,kka2_1:4,P00552,1.30814,NO,199,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.234,-4.316,2.082,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.168804,0.00854122,1.30814 kka2_1:4_L243H,kka2_1:4_243,Kka2,kka2_1:4,P00552,1.30827,NO,243,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-2.651,-3.263,0.612,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.168804,0.00884927,1.30827 kka2_1:2_A137F,kka2_1:2_137,Kka2,kka2_1:2,P00552,1.3083,NO,137,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.156,-3.905,1.749,,0.029,H,A,0.46,0.34,1.323,,63.26,PHB,-2.559,0.295029,0.00515054,1.3083 beta-lactamase_0_H110W,beta-lactamase_0_110,TEM-1,beta-lactamase_0,P62593,1.30835,NO,110,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-1.706,-5.185,3.479,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.0500837,0.00441499,1.30835 kka2_1:4_Q27N,kka2_1:4_27,Kka2,kka2_1:4,P00552,1.30844,NO,27,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-1.659,-3.726,2.067,,0.608,,A,0.4,0.71,1.498,,65.53,PPP,-1.90733,0.168804,0.00595365,1.30844 kka2_1:4_T73M,kka2_1:4_73,Kka2,kka2_1:4,P00552,1.30882,NO,73,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.51,-3.216,0.706,,0.309,H,A,0.22,0.35,1.53,,56.06,PPO,-2.02333,0.168804,0.00628605,1.30882 kka2_1:4_S114M,kka2_1:4_114,Kka2,kka2_1:4,P00552,1.30932,NO,114,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.527,-3.615,1.088,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.168804,0.00705262,1.30932 kka2_1:4_R177Q,kka2_1:4_177,Kka2,kka2_1:4,P00552,1.30934,NO,177,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.282,-3.061,0.779,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.168804,0.00768224,1.30934 kka2_1:4_Q4S,kka2_1:4_4,Kka2,kka2_1:4,P00552,1.30946,NO,4,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.361,-2.105,-0.256,,,,,,,2.026,,71.59,APA,-1.95533,0.168804,0.00239179,1.30946 kka2_1:4_Y218W,kka2_1:4_218,Kka2,kka2_1:4,P00552,1.30951,NO,218,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-1.438,-3.229,1.791,,0.122,H,A,0.21,-0.69,1.022,,56.06,BHP,-1.17533,0.168804,0.0126098,1.30951 kka2_1:8_S11M,kka2_1:8_11,Kka2,kka2_1:8,P00552,1.30967,NO,11,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.322,-2.896,0.574,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.100394,0.00381691,1.30967 kka2_1:8_S11M,kka2_1:8_11,Kka2,kka2_1:8,P00552,1.30967,NO,11,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.322,-2.896,0.574,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.100394,0.00381691,1.30967 kka2_1:4_T130S,kka2_1:4_130,Kka2,kka2_1:4,P00552,1.30977,NO,130,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.392,-2.025,-0.367,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.168804,0.00804204,1.30977 kka2_1:8_G43A,kka2_1:8_43,Kka2,kka2_1:8,P00552,1.30977,NO,43,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.587,-2.77,1.183,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.100394,0.0071925,1.30977 kka2_1:8_G43A,kka2_1:8_43,Kka2,kka2_1:8,P00552,1.30977,NO,43,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.587,-2.77,1.183,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.100394,0.0071925,1.30977 kka2_1:8_R173E,kka2_1:8_173,Kka2,kka2_1:8,P00552,1.30981,NO,173,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.407,-1.731,-0.676,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.100394,0.00784999,1.30981 kka2_1:8_R173E,kka2_1:8_173,Kka2,kka2_1:8,P00552,1.30981,NO,173,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.407,-1.731,-0.676,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.100394,0.00784999,1.30981 kka2_1:4_Q252D,kka2_1:4_252,Kka2,kka2_1:4,P00552,1.30983,NO,252,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.63,-2.481,-0.149,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.168804,0.0121001,1.30983 kka2_1:4_G43A,kka2_1:4_43,Kka2,kka2_1:4,P00552,1.30984,NO,43,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.587,-2.77,1.183,,0.862,T,l,0.75,-0.67,2.247,,63.26,POB,-2.18533,0.168804,0.0071925,1.30984 beta-lactamase_0_L160Q,beta-lactamase_0_160,TEM-1,beta-lactamase_0,P62593,1.30986,NO,160,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.977,-4.199,3.222,,0.022,,B,0.55,-0.6,0.68,,44.41,BHA,-0.936,0.0500837,0.00193775,1.30986 kka2_1:2_A110L,kka2_1:2_110,Kka2,kka2_1:2,P00552,1.3099,NO,110,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.064,-2.329,0.265,,0.175,H,A,0.46,-1.19,23.237,23.237,71.59,OHA,-1.91867,0.295029,0.00759851,1.3099 kka2_1:4_A248T,kka2_1:4_248,Kka2,kka2_1:4,P00552,1.30997,NO,248,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.124,-3.092,0.968,,0.825,S,b,0.46,0.46,,,92.05,HHO,-2.15,0.168804,0.0125484,1.30997 kka2_1:2_R258K,kka2_1:2_258,Kka2,kka2_1:2,P00552,1.3102,NO,258,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.626,-3.325,1.699,,0.316,H,A,1.2,-0.85,7.485,7.485,53.03,HBH,-1.25933,0.295029,0.00983174,1.3102 kka2_1:2_S11A,kka2_1:2_11,Kka2,kka2_1:2,P00552,1.31037,NO,11,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.322,-2.34,0.018,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.295029,0.00381691,1.31037 kka2_1:4_V83K,kka2_1:4_83,Kka2,kka2_1:4,P00552,1.31042,NO,83,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-2.567,-3.653,1.086,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.168804,0.00650486,1.31042 kka2_1:2_R143T,kka2_1:2_143,Kka2,kka2_1:2,P00552,1.31047,NO,143,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.525,-2.557,0.032,,0.325,H,A,0.16,1.22,14.853,14.853,65.53,ABH,-1.86833,0.295029,0.00662247,1.31047 kka2_1:2_F37Y,kka2_1:2_37,Kka2,kka2_1:2,P00552,1.31093,NO,37,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.427,-2.628,1.201,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.295029,0.00586193,1.31093 beta-lactamase_0_I140V,beta-lactamase_0_140,TEM-1,beta-lactamase_0,P62593,1.31098,NO,140,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.733,-1.662,-0.071,,0.128,H,A,0.48,0.41,4.714,,73.08,PHO,-1.48733,0.0500837,0.00597777,1.31098 kka2_1:4_R239H,kka2_1:4_239,Kka2,kka2_1:4,P00552,1.31098,NO,239,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.949,-2.896,-0.053,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.168804,0.00835326,1.31098 kka2_1:4_A172Q,kka2_1:4_172,Kka2,kka2_1:4,P00552,1.31115,NO,172,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.757,-3.279,1.522,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.168804,0.0079265,1.31115 kka2_1:2_S68R,kka2_1:2_68,Kka2,kka2_1:2,P00552,1.31127,NO,68,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.623,-1.749,-0.874,,0.48,H,A,0.27,-0.1,2.655,,71.59,HPH,-1.40767,0.295029,0.00608265,1.31127 kka2_1:4_L7D,kka2_1:4_7,Kka2,kka2_1:4,P00552,1.31168,NO,7,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.926,-2.297,0.371,,,,,,,3.012,,71.59,OHB,-2.12333,0.168804,0.00269456,1.31168 beta-lactamase_0_T138I,beta-lactamase_0_138,TEM-1,beta-lactamase_0,P62593,1.31176,NO,138,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-2.506,-4.099,1.593,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.0500837,0.00487868,1.31176 kka2_1:2_A9L,kka2_1:2_9,Kka2,kka2_1:2,P00552,1.31179,NO,9,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.079,-2.291,0.212,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.295029,0.00273264,1.31179 kka2_1:2_R145K,kka2_1:2_145,Kka2,kka2_1:2,P00552,1.31179,NO,145,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.804,-2.124,0.32,,0.346,H,A,1.2,1.23,7.961,,63.64,HBP,-1.88033,0.295029,0.00846663,1.31179 kka2_1:4_A172R,kka2_1:4_172,Kka2,kka2_1:4,P00552,1.31182,NO,172,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.757,-2.665,0.908,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.168804,0.0079265,1.31182 kka2_1:2_I2P,kka2_1:2_2,Kka2,kka2_1:2,P00552,1.31189,NO,2,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.787,-3.734,1.947,,,,,,,5.773,,71.59,HHA,-1.92433,0.295029,0.00246644,1.31189 kka2_1:4_S114K,kka2_1:4_114,Kka2,kka2_1:4,P00552,1.31198,NO,114,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.527,-3.596,1.069,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.168804,0.00705262,1.31198 kka2_1:4_Q42I,kka2_1:4_42,Kka2,kka2_1:4,P00552,1.31201,NO,42,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.907,-4.147,1.24,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.168804,0.00679212,1.31201 kka2_1:4_I141V,kka2_1:4_141,Kka2,kka2_1:4,P00552,1.31204,NO,141,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.495,-1.912,0.417,,0.068,H,A,0.48,-0.01,2.144,,92.05,BHA,-1.689,0.168804,0.00744745,1.31204 kka2_1:4_T72Q,kka2_1:4_72,Kka2,kka2_1:4,P00552,1.31215,NO,72,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.38,-2.662,0.282,,0.784,H,A,0.82,0.29,6.463,,65.53,HPP,-2.238,0.168804,0.00750756,1.31215 beta-lactamase_0_E108M,beta-lactamase_0_108,TEM-1,beta-lactamase_0,P62593,1.31218,NO,108,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.46,-4.775,3.315,,0.572,G,A,1.04,1.87,8.602,8.602,72.73,PAB,-1.437,0.0500837,0.00413372,1.31218 kka2_1:2_H139I,kka2_1:2_139,Kka2,kka2_1:2,P00552,1.3123,NO,139,H,I,HI,PositiveCharge,Hydrophobic,7.59,6.02,-1.57,94,155,131,-24,153.2,166.7,13.5,-2.809,-3.326,0.517,,0.471,H,A,0.87,0.68,13.912,13.912,63.64,BBB,-2.22,0.295029,0.00734779,1.3123 beta-lactamase_0_E119G,beta-lactamase_0_119,TEM-1,beta-lactamase_0,P62593,1.31236,NO,119,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.412,-2.405,0.993,,0.358,H,A,1.04,0.51,3.396,,63.99,BAH,-1.623,0.0500837,0.00386966,1.31236 kka2_1:2_H139L,kka2_1:2_139,Kka2,kka2_1:2,P00552,1.31243,NO,139,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-2.809,-2.514,-0.295,,0.471,H,A,0.87,0.68,13.912,13.912,63.64,BBB,-2.22,0.295029,0.00734779,1.31243 kka2_1:4_W91Y,kka2_1:4_91,Kka2,kka2_1:4,P00552,1.31263,NO,91,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-1.178,-2.672,1.494,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.168804,0.00358653,1.31263 kka2_1:4_A166D,kka2_1:4_166,Kka2,kka2_1:4,P00552,1.31265,NO,166,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.407,-2.968,0.561,,0.534,.,B,0.46,1.03,,,71.59,HHO,-2.421,0.168804,0.00799912,1.31265 kka2_1:2_I246L,kka2_1:2_246,Kka2,kka2_1:2,P00552,1.3127,NO,246,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-2.008,-2.197,0.189,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.295029,0.0139479,1.3127 kka2_1:4_V242R,kka2_1:4_242,Kka2,kka2_1:4,P00552,1.3128,NO,242,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-2.687,-2.299,-0.388,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.168804,0.0102575,1.3128 kka2_1:2_T130K,kka2_1:2_130,Kka2,kka2_1:2,P00552,1.31283,NO,130,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.392,-3.096,0.704,,0.561,G,A,0.22,0.77,0.5,,92.05,HPO,-1.62633,0.295029,0.00804204,1.31283 kka2_1:4_L165H,kka2_1:4_165,Kka2,kka2_1:4,P00552,1.31303,NO,165,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-2.453,-4.763,2.31,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.168804,0.00801161,1.31303 kka2_1:2_A71Q,kka2_1:2_71,Kka2,kka2_1:2,P00552,1.31306,NO,71,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.824,-2.665,0.841,,0.553,H,A,0.46,0.08,9.788,,64.39,HHP,-1.74033,0.295029,0.00727707,1.31306 beta-lactamase_0_C121A,beta-lactamase_0_121,TEM-1,beta-lactamase_0,P62593,1.31316,NO,121,C,A,CA,Special,Hydrophobic,5.07,6,0.93,195,121,89,-32,108.5,88.6,-19.9,-0.953,-2.902,1.949,,,H,A,0.46,-0.81,3.302,,63.29,HOP,-1.46767,0.0500837,0.000744322,1.31316 kka2_1:2_P98K,kka2_1:2_98,Kka2,kka2_1:2,P00552,1.3136,NO,98,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.526,-2.937,1.411,,0.391,S,B,0.52,-0.65,2.82,,63.26,HOO,-1.19167,0.295029,0.00622754,1.3136 kka2_1:4_V75M,kka2_1:4_75,Kka2,kka2_1:4,P00552,1.31364,NO,75,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-2.06,-2.759,0.699,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.168804,0.00693733,1.31364 beta-lactamase_0_V72Q,beta-lactamase_0_72,TEM-1,beta-lactamase_0,P62593,1.31375,NO,72,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.658,-4.185,2.527,,,H,A,0.44,-1.03,2.964,,65.73,BHH,-1.32167,0.0500837,0.00501194,1.31375 kka2_1:4_Q136I,kka2_1:4_136,Kka2,kka2_1:4,P00552,1.31376,NO,136,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-3.021,-4.106,1.085,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.168804,0.00624149,1.31376 kka2_1:4_A129T,kka2_1:4_129,Kka2,kka2_1:4,P00552,1.31391,NO,129,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.656,-2.639,0.983,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.168804,0.00726862,1.31391 kka2_1:4_H139L,kka2_1:4_139,Kka2,kka2_1:4,P00552,1.31428,NO,139,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-2.809,-2.514,-0.295,,0.471,H,A,0.17,0.68,12.761,12.761,63.64,BBB,-2.22,0.168804,0.00734779,1.31428 kka2_1:8_A168Q,kka2_1:8_168,Kka2,kka2_1:8,P00552,1.31443,NO,168,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.989,-2.544,0.555,,0.67,H,A,0.46,0.15,11.329,11.329,64.39,OHA,-2.12933,0.100394,0.00806773,1.31443 kka2_1:8_A168Q,kka2_1:8_168,Kka2,kka2_1:8,P00552,1.31443,NO,168,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.989,-2.544,0.555,,0.67,H,A,0.46,0.15,11.329,11.329,64.39,OHA,-2.12933,0.100394,0.00806773,1.31443 kka2_1:4_D33T,kka2_1:4_33,Kka2,kka2_1:4,P00552,1.31447,NO,33,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.186,-2.647,0.461,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.168804,0.00633568,1.31447 kka2_1:4_H8V,kka2_1:4_8,Kka2,kka2_1:4,P00552,1.31482,NO,8,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-2.759,-3.205,0.446,,,,,,,,,71.59,HBH,-2.25467,0.168804,0.00256422,1.31482 kka2_1:4_L47F,kka2_1:4_47,Kka2,kka2_1:4,P00552,1.31522,NO,47,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.265,-2.523,1.258,,0.139,E,B,0.55,-0.86,2.369,,63.26,HHH,-1.77933,0.168804,0.00509386,1.31522 kka2_1:8_E235H,kka2_1:8_235,Kka2,kka2_1:8,P00552,1.31531,NO,235,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.955,-4.699,2.744,,0.631,H,A,1.52,0.12,,,65.53,OAH,-2.07267,0.100394,0.0102806,1.31531 kka2_1:8_E235H,kka2_1:8_235,Kka2,kka2_1:8,P00552,1.31531,NO,235,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.955,-4.699,2.744,,0.631,H,A,1.52,0.12,,,65.53,OAH,-2.07267,0.100394,0.0102806,1.31531 beta-lactamase_0_F228K,beta-lactamase_0_228,TEM-1,beta-lactamase_0,P62593,1.31535,NO,228,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-2.342,-2.864,0.522,,0.154,E,B,0.58,-0.42,15.504,15.504,63.29,HHH,-1.53033,0.0500837,0.0046669,1.31535 beta-lactamase_0_F228C,beta-lactamase_0_228,TEM-1,beta-lactamase_0,P62593,1.31539,NO,228,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-2.342,-5.075,2.733,,0.154,E,B,0.58,-0.42,15.504,15.504,63.29,HHH,-1.53033,0.0500837,0.0046669,1.31539 kka2_1:4_A168K,kka2_1:4_168,Kka2,kka2_1:4,P00552,1.31553,NO,168,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.989,-2.846,0.857,,0.67,H,A,0.46,0.15,,,64.39,OHA,-2.12933,0.168804,0.00806773,1.31553 kka2_1:4_D5Q,kka2_1:4_5,Kka2,kka2_1:4,P00552,1.31553,NO,5,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.306,-3.312,2.006,,,,,,,,,71.59,PAO,-1.784,0.168804,0.00222864,1.31553 beta-lactamase_0_E87Q,beta-lactamase_0_87,TEM-1,beta-lactamase_0,P62593,1.31573,NO,87,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.421,-2.648,1.227,,0.048,,B,1.04,0.92,1.159,,64.69,PAP,-1.969,0.0500837,0.00337888,1.31573 kka2_1:8_G234H,kka2_1:8_234,Kka2,kka2_1:8,P00552,1.31582,NO,234,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-2.9,-4.698,1.798,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.100394,0.00984449,1.31582 kka2_1:8_G234H,kka2_1:8_234,Kka2,kka2_1:8,P00552,1.31582,NO,234,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-2.9,-4.698,1.798,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.100394,0.00984449,1.31582 kka2_1:8_T225M,kka2_1:8_225,Kka2,kka2_1:8,P00552,1.31593,NO,225,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.393,-3.418,1.025,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.100394,0.0113598,1.31593 kka2_1:8_T225M,kka2_1:8_225,Kka2,kka2_1:8,P00552,1.31593,NO,225,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.393,-3.418,1.025,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.100394,0.0113598,1.31593 kka2_1:4_L165A,kka2_1:4_165,Kka2,kka2_1:4,P00552,1.31601,NO,165,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-2.453,-2.69,0.237,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.168804,0.00801161,1.31601 kka2_1:4_E160Q,kka2_1:4_160,Kka2,kka2_1:4,P00552,1.31612,NO,160,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.683,-3.734,2.051,,0.989,G,A,1.04,2.28,2.531,,71.59,AAA,-1.36133,0.168804,0.00935762,1.31612 kka2_1:2_L47Q,kka2_1:2_47,Kka2,kka2_1:2,P00552,1.31624,NO,47,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.265,-2.824,1.559,,0.139,E,B,0.55,-0.86,2.369,,63.26,HHH,-1.77933,0.295029,0.00509386,1.31624 kka2_1:8_S40T,kka2_1:8_40,Kka2,kka2_1:8,P00552,1.31629,NO,40,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.645,-2.259,-0.386,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.100394,0.00693477,1.31629 kka2_1:8_S40T,kka2_1:8_40,Kka2,kka2_1:8,P00552,1.31629,NO,40,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.645,-2.259,-0.386,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.100394,0.00693477,1.31629 beta-lactamase_0_K232F,beta-lactamase_0_232,TEM-1,beta-lactamase_0,P62593,1.31655,NO,232,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.012,-4.334,3.322,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.0500837,0.00313441,1.31655 kka2_1:8_V46N,kka2_1:8_46,Kka2,kka2_1:8,P00552,1.31656,NO,46,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-2.62,-3.225,0.605,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.100394,0.00631301,1.31656 kka2_1:8_V46N,kka2_1:8_46,Kka2,kka2_1:8,P00552,1.31656,NO,46,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-2.62,-3.225,0.605,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.100394,0.00631301,1.31656 kka2_1:4_H106K,kka2_1:4_106,Kka2,kka2_1:4,P00552,1.31666,NO,106,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-3.13,-3.67,0.54,,1.065,.,a,0.17,-0.95,16.74,16.74,71.59,PBH,-2.10433,0.168804,0.00730778,1.31666 kka2_1:4_L165I,kka2_1:4_165,Kka2,kka2_1:4,P00552,1.3168,NO,165,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-2.453,-3.855,1.402,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.168804,0.00801161,1.3168 kka2_1:4_S11Y,kka2_1:4_11,Kka2,kka2_1:4,P00552,1.31682,NO,11,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.322,-4.097,1.775,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.168804,0.00381691,1.31682 kka2_1:4_D250E,kka2_1:4_250,Kka2,kka2_1:4,P00552,1.31686,NO,250,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.015,-2.129,1.114,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.168804,0.0177103,1.31686 kka2_1:8_G234Y,kka2_1:8_234,Kka2,kka2_1:8,P00552,1.31704,NO,234,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-2.9,-4.454,1.554,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.100394,0.00984449,1.31704 kka2_1:8_G234Y,kka2_1:8_234,Kka2,kka2_1:8,P00552,1.31704,NO,234,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-2.9,-4.454,1.554,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.100394,0.00984449,1.31704 kka2_1:8_Q252D,kka2_1:8_252,Kka2,kka2_1:8,P00552,1.31704,NO,252,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.63,-2.481,-0.149,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.100394,0.0121001,1.31704 kka2_1:8_Q252D,kka2_1:8_252,Kka2,kka2_1:8,P00552,1.31704,NO,252,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.63,-2.481,-0.149,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.100394,0.0121001,1.31704 beta-lactamase_0_E87I,beta-lactamase_0_87,TEM-1,beta-lactamase_0,P62593,1.31705,NO,87,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.421,-3.687,2.266,,0.048,,B,1.04,0.92,1.159,,64.69,PAP,-1.969,0.0500837,0.00337888,1.31705 beta-lactamase_0_T158I,beta-lactamase_0_158,TEM-1,beta-lactamase_0,P62593,1.31714,NO,158,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.116,-3.731,2.615,,0.036,,B,0.22,-0.85,1.041,,69.58,HPB,-1.269,0.0500837,0.00341825,1.31714 kka2_1:4_Q42S,kka2_1:4_42,Kka2,kka2_1:4,P00552,1.31722,NO,42,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.907,-2.69,-0.217,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.168804,0.00679212,1.31722 beta-lactamase_0_A132M,beta-lactamase_0_132,TEM-1,beta-lactamase_0,P62593,1.31729,NO,132,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-0.9,-4.473,3.573,,,H,A,0.46,-0.93,2.249,,64.69,PHH,-1.138,0.0500837,0.000962524,1.31729 kka2_1:4_G181W,kka2_1:4_181,Kka2,kka2_1:4,P00552,1.31733,NO,181,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-2.698,-5.561,2.863,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.168804,0.00728319,1.31733 kka2_1:2_S251F,kka2_1:2_251,Kka2,kka2_1:2,P00552,1.31737,NO,251,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.636,-4.475,1.839,,0.712,H,A,0.27,-0.25,32.832,32.832,71.59,APP,-2.09367,0.295029,0.0138916,1.31737 beta-lactamase_0_E108H,beta-lactamase_0_108,TEM-1,beta-lactamase_0,P62593,1.31744,NO,108,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.46,-4.53,3.07,,0.572,G,A,1.04,1.87,8.602,8.602,72.73,PAB,-1.437,0.0500837,0.00413372,1.31744 kka2_1:2_E199Q,kka2_1:2_199,Kka2,kka2_1:2,P00552,1.31771,NO,199,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.234,-3.039,0.805,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.295029,0.00854122,1.31771 kka2_1:2_Q163F,kka2_1:2_163,Kka2,kka2_1:2,P00552,1.31781,NO,163,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.162,-4.196,2.034,,0.58,T,B,0.64,1.85,3.888,,64.02,BPO,-1.78333,0.295029,0.00719507,1.31781 kka2_1:8_V46C,kka2_1:8_46,Kka2,kka2_1:8,P00552,1.31799,NO,46,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-2.62,-3.346,0.726,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.100394,0.00631301,1.31799 kka2_1:8_V46C,kka2_1:8_46,Kka2,kka2_1:8,P00552,1.31799,NO,46,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-2.62,-3.346,0.726,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.100394,0.00631301,1.31799 kka2_1:4_G151D,kka2_1:4_151,Kka2,kka2_1:4,P00552,1.31805,NO,151,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-0.873,-2.683,1.81,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.168804,0.00339918,1.31805 kka2_1:4_A9G,kka2_1:4_9,Kka2,kka2_1:4,P00552,1.31809,NO,9,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.079,-3.28,1.201,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.168804,0.00273264,1.31809 kka2_1:2_V75L,kka2_1:2_75,Kka2,kka2_1:2,P00552,1.31818,NO,75,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-2.06,-1.581,-0.479,,0.042,.,B,0.44,-0.2,2.815,,71.59,OHO,-1.563,0.295029,0.00693733,1.31818 kka2_1:2_H8L,kka2_1:2_8,Kka2,kka2_1:2,P00552,1.31822,NO,8,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-2.759,-3.165,0.406,,,,,,,,,71.59,HBH,-2.25467,0.295029,0.00256422,1.31822 kka2_1:2_V242C,kka2_1:2_242,Kka2,kka2_1:2,P00552,1.31858,NO,242,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-2.687,-5.161,2.474,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.295029,0.0102575,1.31858 kka2_1:4_A255N,kka2_1:4_255,Kka2,kka2_1:4,P00552,1.31874,NO,255,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.715,-3.829,2.114,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.168804,0.0126809,1.31874 beta-lactamase_0_T147D,beta-lactamase_0_147,TEM-1,beta-lactamase_0,P62593,1.31878,NO,147,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.149,-3.491,2.342,,0.281,H,A,0.22,-0.68,3.487,,64.34,HPH,-1.456,0.0500837,0.00226017,1.31878 kka2_1:4_T125S,kka2_1:4_125,Kka2,kka2_1:4,P00552,1.31882,NO,125,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.622,-2.445,-0.177,,0.791,T,A,0.82,0.33,1.612,,92.05,BPH,-1.56933,0.168804,0.00821755,1.31882 kka2_1:4_A25L,kka2_1:4_25,Kka2,kka2_1:4,P00552,1.31884,NO,25,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.496,-3.561,1.065,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.168804,0.00595636,1.31884 kka2_1:4_T73E,kka2_1:4_73,Kka2,kka2_1:4,P00552,1.31889,NO,73,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.51,-2.977,0.467,,0.309,H,A,0.22,0.35,1.53,,56.06,PPO,-2.02333,0.168804,0.00628605,1.31889 kka2_1:4_Q4A,kka2_1:4_4,Kka2,kka2_1:4,P00552,1.31905,NO,4,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.361,-2.857,0.496,,,,,,,2.026,,71.59,APA,-1.95533,0.168804,0.00239179,1.31905 kka2_1:2_A35T,kka2_1:2_35,Kka2,kka2_1:2,P00552,1.31919,NO,35,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.127,-2.654,0.527,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.295029,0.00630016,1.31919 kka2_1:4_E149H,kka2_1:4_149,Kka2,kka2_1:4,P00552,1.31943,NO,149,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.994,-3.508,1.514,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.168804,0.00803343,1.31943 kka2_1:4_A247G,kka2_1:4_247,Kka2,kka2_1:4,P00552,1.31954,NO,247,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.459,-2.518,0.059,,1.01,S,A,0.46,0.65,,,92.05,HHH,-2.197,0.168804,0.0102428,1.31954 kka2_1:2_D5R,kka2_1:2_5,Kka2,kka2_1:2,P00552,1.31955,NO,5,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.306,-3.57,2.264,,,,,,,,,71.59,PAO,-1.784,0.295029,0.00222864,1.31955 kka2_1:4_S114E,kka2_1:4_114,Kka2,kka2_1:4,P00552,1.31955,NO,114,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.527,-2.055,-0.472,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.168804,0.00705262,1.31955 kka2_1:4_D23H,kka2_1:4_23,Kka2,kka2_1:4,P00552,1.31956,NO,23,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.459,-3.07,0.611,,0.695,E,B,0.75,-0.65,2.416,,65.53,HAH,-1.94033,0.168804,0.007195,1.31956 kka2_1:4_K175T,kka2_1:4_175,Kka2,kka2_1:4,P00552,1.31961,NO,175,K,T,KT,PositiveCharge,Polar,9.74,5.6,-4.14,78,146,119,-27,168.6,116.1,-52.5,-2.897,-2.9,0.003,,0.579,H,A,1.3,0.51,15.629,15.629,71.59,HBH,-1.82333,0.168804,0.00693093,1.31961 kka2_1:4_G21H,kka2_1:4_21,Kka2,kka2_1:4,P00552,1.31969,NO,21,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.368,-2.564,1.196,,0.586,T,l,0.75,-0.75,3.075,,71.59,HOH,-2.10167,0.168804,0.00709648,1.31969 kka2_1:8_I2Y,kka2_1:8_2,Kka2,kka2_1:8,P00552,1.31973,NO,2,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.787,-3.837,2.05,,,,,,,,,71.59,HHA,-1.92433,0.100394,0.00246644,1.31973 kka2_1:8_I2Y,kka2_1:8_2,Kka2,kka2_1:8,P00552,1.31973,NO,2,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.787,-3.837,2.05,,,,,,,,,71.59,HHA,-1.92433,0.100394,0.00246644,1.31973 kka2_1:2_V46D,kka2_1:2_46,Kka2,kka2_1:2,P00552,1.3199,NO,46,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-2.62,-2.475,-0.145,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.295029,0.00631301,1.3199 kka2_1:4_T72K,kka2_1:4_72,Kka2,kka2_1:4,P00552,1.32,NO,72,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.38,-2.635,0.255,,0.784,H,A,0.82,0.29,6.463,,65.53,HPP,-2.238,0.168804,0.00750756,1.32 kka2_1:4_A79G,kka2_1:4_79,Kka2,kka2_1:4,P00552,1.32014,NO,79,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.368,-2.844,0.476,,0.563,.,B,0.46,-0.43,2.291,,71.59,HHH,-1.752,0.168804,0.00664821,1.32014 kka2_1:4_D23R,kka2_1:4_23,Kka2,kka2_1:4,P00552,1.32036,NO,23,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.459,-2.183,-0.276,,0.695,E,B,0.75,-0.65,2.416,,65.53,HAH,-1.94033,0.168804,0.007195,1.32036 kka2_1:2_Q252D,kka2_1:2_252,Kka2,kka2_1:2,P00552,1.32043,NO,252,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.63,-2.481,-0.149,,0.906,H,A,0.64,0.35,5.613,,92.05,PPB,-2.20733,0.295029,0.0121001,1.32043 kka2_1:2_H106P,kka2_1:2_106,Kka2,kka2_1:2,P00552,1.32044,NO,106,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-3.13,-2.907,-0.223,,1.065,.,a,0.17,-0.95,2.53,,71.59,PBH,-2.10433,0.295029,0.00730778,1.32044 kka2_1:2_V16A,kka2_1:2_16,Kka2,kka2_1:2,P00552,1.32067,NO,16,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-3.087,-2.407,-0.68,,0.742,T,A,0.44,0.34,1.746,,71.59,HHA,-2.211,0.295029,0.00694011,1.32067 kka2_1:4_T73A,kka2_1:4_73,Kka2,kka2_1:4,P00552,1.32078,NO,73,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.51,-2.502,-0.008,,0.309,H,A,0.22,0.35,1.53,,56.06,PPO,-2.02333,0.168804,0.00628605,1.32078 kka2_1:2_S251E,kka2_1:2_251,Kka2,kka2_1:2,P00552,1.3208,NO,251,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.636,-2.355,-0.281,,0.712,H,A,0.27,-0.25,32.832,32.832,71.59,APP,-2.09367,0.295029,0.0138916,1.3208 kka2_1:2_K175I,kka2_1:2_175,Kka2,kka2_1:2,P00552,1.32082,NO,175,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-2.897,-2.932,0.035,,0.579,H,A,1.3,0.51,15.629,15.629,71.59,HBH,-1.82333,0.295029,0.00693093,1.32082 kka2_1:2_R173Q,kka2_1:2_173,Kka2,kka2_1:2,P00552,1.32088,NO,173,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.407,-2.729,0.322,,0.308,H,A,0.16,-0.13,15.389,15.389,65.53,HBH,-1.70533,0.295029,0.00784999,1.32088 kka2_1:8_G234I,kka2_1:8_234,Kka2,kka2_1:8,P00552,1.32092,NO,234,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-2.9,-4.067,1.167,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.100394,0.00984449,1.32092 kka2_1:8_G234I,kka2_1:8_234,Kka2,kka2_1:8,P00552,1.32092,NO,234,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-2.9,-4.067,1.167,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.100394,0.00984449,1.32092 kka2_1:4_D5M,kka2_1:4_5,Kka2,kka2_1:4,P00552,1.32094,NO,5,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.306,-4.66,3.354,,,,,,,,,71.59,PAO,-1.784,0.168804,0.00222864,1.32094 kka2_1:4_R143V,kka2_1:4_143,Kka2,kka2_1:4,P00552,1.321,NO,143,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.525,-2.516,-0.009,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.168804,0.00662247,1.321 kka2_1:4_E3L,kka2_1:4_3,Kka2,kka2_1:4,P00552,1.32106,NO,3,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.199,-3.455,1.256,,,,,,,7.22,,92.05,HAP,-2.11567,0.168804,0.00267607,1.32106 kka2_1:2_S11T,kka2_1:2_11,Kka2,kka2_1:2,P00552,1.32136,NO,11,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.322,-3.33,1.008,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.295029,0.00381691,1.32136 kka2_1:4_L126I,kka2_1:4_126,Kka2,kka2_1:4,P00552,1.3214,NO,126,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.246,-2.028,0.782,,0.285,S,B,0.55,0.12,0.302,,51.89,PHA,-1.744,0.168804,0.0066485,1.3214 kka2_1:2_G43D,kka2_1:2_43,Kka2,kka2_1:2,P00552,1.32146,NO,43,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.587,-2.025,0.438,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.295029,0.0071925,1.32146 beta-lactamase_0_T179D,beta-lactamase_0_179,TEM-1,beta-lactamase_0,P62593,1.32184,NO,179,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.085,-3.517,2.432,,,E,B,0.22,-1.38,0.367,,73.08,PPH,-1.557,0.0500837,0.00226045,1.32184 kka2_1:2_S251L,kka2_1:2_251,Kka2,kka2_1:2,P00552,1.32197,NO,251,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.636,-2.87,0.234,,0.712,H,A,0.27,-0.25,32.832,32.832,71.59,APP,-2.09367,0.295029,0.0138916,1.32197 kka2_1:2_D5T,kka2_1:2_5,Kka2,kka2_1:2,P00552,1.32203,NO,5,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.306,-3.232,1.926,,,,,,,,,71.59,PAO,-1.784,0.295029,0.00222864,1.32203 kka2_1:4_Q61L,kka2_1:4_61,Kka2,kka2_1:4,P00552,1.32218,NO,61,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.982,-2.984,0.002,,0.591,H,A,0.64,0.41,3.484,,65.53,HPA,-1.85667,0.168804,0.00612092,1.32218 beta-lactamase_0_E272A,beta-lactamase_0_272,TEM-1,beta-lactamase_0,P62593,1.32231,NO,272,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.0500837,0.00545371,1.32231 kka2_1:4_P249E,kka2_1:4_249,Kka2,kka2_1:4,P00552,1.3226,NO,249,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.867,-3.804,1.937,,0.406,.,B,0.52,-0.01,,,92.05,HOA,-1.66867,0.168804,0.011045,1.3226 kka2_1:4_E199C,kka2_1:4_199,Kka2,kka2_1:4,P00552,1.3227,NO,199,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.234,-3.64,1.406,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.168804,0.00854122,1.3227 kka2_1:2_V83Q,kka2_1:2_83,Kka2,kka2_1:2,P00552,1.32286,NO,83,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-2.567,-3.072,0.505,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.295029,0.00650486,1.32286 kka2_1:2_M178Q,kka2_1:2_178,Kka2,kka2_1:2,P00552,1.32295,NO,178,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-3.206,-2.478,-0.728,,0.554,.,b,0.55,0.68,3.152,,71.59,BHO,-2.154,0.295029,0.00717253,1.32295 kka2_1:4_P179F,kka2_1:4_179,Kka2,kka2_1:4,P00552,1.32321,NO,179,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.974,-4.355,3.381,,0.113,,B,0.52,0.69,10.913,10.913,56.06,HOA,-2.19867,0.168804,0.00298346,1.32321 kka2_1:4_R122W,kka2_1:4_122,Kka2,kka2_1:4,P00552,1.32321,NO,122,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.175,-5.581,3.406,,0.487,H,A,0.16,0.26,16.436,16.436,71.59,BBH,-1.53833,0.168804,0.00736512,1.32321 kka2_1:4_Q100T,kka2_1:4_100,Kka2,kka2_1:4,P00552,1.32343,NO,100,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.77,-2.757,-0.013,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.168804,0.0066405,1.32343 kka2_1:4_E17S,kka2_1:4_17,Kka2,kka2_1:4,P00552,1.32347,NO,17,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.154,-2.653,0.499,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.168804,0.00688738,1.32347 kka2_1:4_H106E,kka2_1:4_106,Kka2,kka2_1:4,P00552,1.32347,NO,106,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-3.13,-2.347,-0.783,,1.065,.,a,0.17,-0.95,16.74,16.74,71.59,PBH,-2.10433,0.168804,0.00730778,1.32347 kka2_1:4_L158W,kka2_1:4_158,Kka2,kka2_1:4,P00552,1.32349,NO,158,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.947,-4.75,2.803,,0.095,,B,1.59,0.77,7.588,,63.64,AHA,-1.25333,0.168804,0.00529068,1.32349 kka2_1:2_A9Q,kka2_1:2_9,Kka2,kka2_1:2,P00552,1.32359,NO,9,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.079,-3.919,1.84,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.295029,0.00273264,1.32359 kka2_1:4_R173W,kka2_1:4_173,Kka2,kka2_1:4,P00552,1.32361,NO,173,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.407,-3.224,0.817,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.168804,0.00784999,1.32361 kka2_1:4_A14I,kka2_1:4_14,Kka2,kka2_1:4,P00552,1.32377,NO,14,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.837,-3.179,1.342,,0.728,G,A,0.46,0.7,0.36,,71.59,HHH,-1.82567,0.168804,0.00706614,1.32377 kka2_1:4_G181Y,kka2_1:4_181,Kka2,kka2_1:4,P00552,1.32384,NO,181,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-2.698,-3.473,0.775,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.168804,0.00728319,1.32384 beta-lactamase_0_A222R,beta-lactamase_0_222,TEM-1,beta-lactamase_0,P62593,1.32386,NO,222,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.103,-4.005,1.902,,0.233,H,A,0.46,-0.25,2.015,,77.62,PHH,-1.63733,0.0500837,0.00466094,1.32386 kka2_1:8_A168F,kka2_1:8_168,Kka2,kka2_1:8,P00552,1.32399,NO,168,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.989,-3.458,1.469,,0.67,H,A,0.46,0.15,11.329,11.329,64.39,OHA,-2.12933,0.100394,0.00806773,1.32399 kka2_1:8_A168F,kka2_1:8_168,Kka2,kka2_1:8,P00552,1.32399,NO,168,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.989,-3.458,1.469,,0.67,H,A,0.46,0.15,11.329,11.329,64.39,OHA,-2.12933,0.100394,0.00806773,1.32399 kka2_1:4_Q163V,kka2_1:4_163,Kka2,kka2_1:4,P00552,1.32428,NO,163,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.162,-2.687,0.525,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.168804,0.00719507,1.32428 kka2_1:8_A247M,kka2_1:8_247,Kka2,kka2_1:8,P00552,1.32461,NO,247,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.459,-3.49,1.031,,1.01,S,A,0.46,0.65,18.904,18.904,92.05,HHH,-2.197,0.100394,0.0102428,1.32461 kka2_1:8_A247M,kka2_1:8_247,Kka2,kka2_1:8,P00552,1.32461,NO,247,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.459,-3.49,1.031,,1.01,S,A,0.46,0.65,18.904,18.904,92.05,HHH,-2.197,0.100394,0.0102428,1.32461 beta-lactamase_0_G39Q,beta-lactamase_0_39,TEM-1,beta-lactamase_0,P62593,1.32466,NO,39,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.864,-2.885,1.021,,0.701,T,L,0.29,0.47,4.111,,77.62,HOH,-1.53633,0.0500837,0.00487611,1.32466 kka2_1:4_D238W,kka2_1:4_238,Kka2,kka2_1:4,P00552,1.32466,NO,238,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.83,-5.568,2.738,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.168804,0.0113863,1.32466 beta-lactamase_0_V106N,beta-lactamase_0_106,TEM-1,beta-lactamase_0,P62593,1.32471,NO,106,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.218,-4.217,2.999,,0.258,T,A,0.44,0.24,0.952,,72.73,OHP,-1.04933,0.0500837,0.00304168,1.32471 kka2_1:2_A168Y,kka2_1:2_168,Kka2,kka2_1:2,P00552,1.32471,NO,168,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.989,-4.327,2.338,,0.67,H,A,0.46,0.15,25.546,25.546,64.39,OHA,-2.12933,0.295029,0.00806773,1.32471 kka2_1:4_D238T,kka2_1:4_238,Kka2,kka2_1:4,P00552,1.32482,NO,238,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.83,-2.681,-0.149,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.168804,0.0113863,1.32482 kka2_1:2_A248R,kka2_1:2_248,Kka2,kka2_1:2,P00552,1.32484,NO,248,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.124,-2.856,0.732,,0.825,S,b,0.46,0.46,,,92.05,HHO,-2.15,0.295029,0.0125484,1.32484 kka2_1:4_A191H,kka2_1:4_191,Kka2,kka2_1:4,P00552,1.32499,NO,191,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.831,-4.743,3.912,,,.,b,0.46,-0.94,2.046,,50,AHO,-0.868667,0.168804,0.00338807,1.32499 kka2_1:4_A35K,kka2_1:4_35,Kka2,kka2_1:4,P00552,1.32507,NO,35,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.127,-3.623,1.496,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.168804,0.00630016,1.32507 beta-lactamase_0_H94M,beta-lactamase_0_94,TEM-1,beta-lactamase_0,P62593,1.32532,NO,94,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-2.5,-3.474,0.974,,0.776,,B,0.17,1.24,1.176,,77.62,HBH,-1.872,0.0500837,0.00389226,1.32532 kka2_1:2_H106A,kka2_1:2_106,Kka2,kka2_1:2,P00552,1.32551,NO,106,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-3.13,-2.399,-0.731,,1.065,.,a,0.17,-0.95,2.53,,71.59,PBH,-2.10433,0.295029,0.00730778,1.32551 kka2_1:4_Q155M,kka2_1:4_155,Kka2,kka2_1:4,P00552,1.32554,NO,155,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.606,-4.733,2.127,,0.525,T,A,0.64,1.49,1.592,,63.64,APA,-1.726,0.168804,0.00641853,1.32554 kka2_1:2_E17D,kka2_1:2_17,Kka2,kka2_1:2,P00552,1.32557,NO,17,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.154,-2.384,0.23,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.295029,0.00688738,1.32557 beta-lactamase_0_L150M,beta-lactamase_0_150,TEM-1,beta-lactamase_0,P62593,1.3256,NO,150,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.326,-2.392,1.066,,,H,A,0.55,-0.2,2.128,,62.94,HHB,-1.86167,0.0500837,0.00463171,1.3256 kka2_1:4_I2M,kka2_1:4_2,Kka2,kka2_1:4,P00552,1.32567,NO,2,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.787,-3.979,2.192,,,,,,,,,71.59,HHA,-1.92433,0.168804,0.00246644,1.32567 kka2_1:4_D238K,kka2_1:4_238,Kka2,kka2_1:4,P00552,1.32594,NO,238,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.83,-2.641,-0.189,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.168804,0.0113863,1.32594 kka2_1:4_Q163Y,kka2_1:4_163,Kka2,kka2_1:4,P00552,1.32627,NO,163,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.162,-4.27,2.108,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.168804,0.00719507,1.32627 kka2_1:8_A41G,kka2_1:8_41,Kka2,kka2_1:8,P00552,1.32628,NO,41,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.879,-2.32,0.441,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.100394,0.00543332,1.32628 kka2_1:8_A41G,kka2_1:8_41,Kka2,kka2_1:8,P00552,1.32628,NO,41,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.879,-2.32,0.441,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.100394,0.00543332,1.32628 kka2_1:2_A172Q,kka2_1:2_172,Kka2,kka2_1:2,P00552,1.32641,NO,172,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.757,-3.279,1.522,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.295029,0.0079265,1.32641 kka2_1:4_R145K,kka2_1:4_145,Kka2,kka2_1:4,P00552,1.32677,NO,145,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.804,-2.124,0.32,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.168804,0.00846663,1.32677 kka2_1:2_E3Q,kka2_1:2_3,Kka2,kka2_1:2,P00552,1.32682,NO,3,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.199,-3.602,1.403,,,,,,,7.22,,92.05,HAP,-2.11567,0.295029,0.00267607,1.32682 kka2_1:8_Q4V,kka2_1:8_4,Kka2,kka2_1:8,P00552,1.32685,NO,4,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.361,-3.536,1.175,,,,,,,2.026,,71.59,APA,-1.95533,0.100394,0.00239179,1.32685 kka2_1:8_Q4V,kka2_1:8_4,Kka2,kka2_1:8,P00552,1.32685,NO,4,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.361,-3.536,1.175,,,,,,,2.026,,71.59,APA,-1.95533,0.100394,0.00239179,1.32685 beta-lactamase_0_V214L,beta-lactamase_0_214,TEM-1,beta-lactamase_0,P62593,1.32686,NO,214,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.299,-2.237,0.938,,0.375,S,A,0.44,-0.44,3.712,,74.48,BHH,-1.53733,0.0500837,0.00628442,1.32686 kka2_1:4_R44A,kka2_1:4_44,Kka2,kka2_1:4,P00552,1.32701,NO,44,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.062,-2.384,0.322,,0.487,S,B,1.2,-0.35,5.71,,71.59,OBO,-1.80767,0.168804,0.00745043,1.32701 kka2_1:4_S11R,kka2_1:4_11,Kka2,kka2_1:4,P00552,1.32705,NO,11,S,R,SR,Polar,PositiveCharge,5.68,6.34148,0.661478,110,105,174,69,89,173.4,84.4,-2.322,-3.926,1.604,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.168804,0.00381691,1.32705 kka2_1:8_S251W,kka2_1:8_251,Kka2,kka2_1:8,P00552,1.32706,NO,251,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.636,-5.587,2.951,,0.712,H,A,0.27,-0.25,,,71.59,APP,-2.09367,0.100394,0.0138916,1.32706 kka2_1:8_S251W,kka2_1:8_251,Kka2,kka2_1:8,P00552,1.32706,NO,251,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.636,-5.587,2.951,,0.712,H,A,0.27,-0.25,,,71.59,APP,-2.09367,0.100394,0.0138916,1.32706 kka2_1:8_Q252T,kka2_1:8_252,Kka2,kka2_1:8,P00552,1.32713,NO,252,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.63,-2.832,0.202,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.100394,0.0121001,1.32713 kka2_1:8_Q252T,kka2_1:8_252,Kka2,kka2_1:8,P00552,1.32713,NO,252,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.63,-2.832,0.202,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.100394,0.0121001,1.32713 kka2_1:2_A9P,kka2_1:2_9,Kka2,kka2_1:2,P00552,1.32734,NO,9,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.079,-2.571,0.492,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.295029,0.00273264,1.32734 kka2_1:2_R143C,kka2_1:2_143,Kka2,kka2_1:2,P00552,1.32743,NO,143,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.525,-5.079,2.554,,0.325,H,A,0.16,1.22,14.853,14.853,65.53,ABH,-1.86833,0.295029,0.00662247,1.32743 kka2_1:2_I2T,kka2_1:2_2,Kka2,kka2_1:2,P00552,1.32753,NO,2,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.787,-2.02,0.233,,,,,,,5.773,,71.59,HHA,-1.92433,0.295029,0.00246644,1.32753 kka2_1:4_A191F,kka2_1:4_191,Kka2,kka2_1:4,P00552,1.32791,NO,191,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.831,-4.183,3.352,,,.,b,0.46,-0.94,2.046,,50,AHO,-0.868667,0.168804,0.00338807,1.32791 kka2_1:4_Q42G,kka2_1:4_42,Kka2,kka2_1:4,P00552,1.32793,NO,42,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.907,-2.492,-0.415,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.168804,0.00679212,1.32793 kka2_1:4_V46A,kka2_1:4_46,Kka2,kka2_1:4,P00552,1.32799,NO,46,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-2.62,-2.194,-0.426,,0.192,.,B,0.44,-1.12,9.564,,92.05,OHH,-1.88633,0.168804,0.00631301,1.32799 kka2_1:4_A56D,kka2_1:4_56,Kka2,kka2_1:4,P00552,1.3281,NO,56,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.083,-2.651,0.568,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.168804,0.00717715,1.3281 kka2_1:4_D180K,kka2_1:4_180,Kka2,kka2_1:4,P00552,1.32825,NO,180,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.416,-2.839,0.423,,1.03,S,a,0.29,1.5,14.668,14.668,71.59,OAO,-2.02933,0.168804,0.00756412,1.32825 kka2_1:4_G43D,kka2_1:4_43,Kka2,kka2_1:4,P00552,1.32831,NO,43,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.587,-2.025,0.438,,0.862,T,l,0.75,-0.67,2.247,,63.26,POB,-2.18533,0.168804,0.0071925,1.32831 kka2_1:4_T125M,kka2_1:4_125,Kka2,kka2_1:4,P00552,1.32841,NO,125,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.622,-4.759,2.137,,0.791,T,A,0.82,0.33,1.612,,92.05,BPH,-1.56933,0.168804,0.00821755,1.32841 kka2_1:8_R173Q,kka2_1:8_173,Kka2,kka2_1:8,P00552,1.32852,NO,173,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.407,-2.729,0.322,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.100394,0.00784999,1.32852 kka2_1:8_R173Q,kka2_1:8_173,Kka2,kka2_1:8,P00552,1.32852,NO,173,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.407,-2.729,0.322,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.100394,0.00784999,1.32852 kka2_1:2_I2R,kka2_1:2_2,Kka2,kka2_1:2,P00552,1.32855,NO,2,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.787,-3.848,2.061,,,,,,,5.773,,71.59,HHA,-1.92433,0.295029,0.00246644,1.32855 kka2_1:4_E161N,kka2_1:4_161,Kka2,kka2_1:4,P00552,1.32879,NO,161,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.581,-3.715,2.134,,0.829,G,A,1.52,2.24,1.612,,92.05,AAB,-1.861,0.168804,0.00760103,1.32879 kka2_1:2_A56D,kka2_1:2_56,Kka2,kka2_1:2,P00552,1.32884,NO,56,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.083,-2.651,0.568,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.295029,0.00717715,1.32884 kka2_1:8_E96Q,kka2_1:8_96,Kka2,kka2_1:8,P00552,1.32886,NO,96,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.573,-3.937,1.364,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.100394,0.00369441,1.32886 kka2_1:8_E96Q,kka2_1:8_96,Kka2,kka2_1:8,P00552,1.32886,NO,96,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.573,-3.937,1.364,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.100394,0.00369441,1.32886 kka2_1:4_G21E,kka2_1:4_21,Kka2,kka2_1:4,P00552,1.32888,NO,21,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.368,-3.414,2.046,,0.586,T,l,0.75,-0.75,3.075,,71.59,HOH,-2.10167,0.168804,0.00709648,1.32888 kka2_1:4_S40A,kka2_1:4_40,Kka2,kka2_1:4,P00552,1.32892,NO,40,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.645,-2.559,-0.086,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.168804,0.00693477,1.32892 kka2_1:4_A172N,kka2_1:4_172,Kka2,kka2_1:4,P00552,1.32895,NO,172,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.757,-3.17,1.413,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.168804,0.0079265,1.32895 kka2_1:4_V80I,kka2_1:4_80,Kka2,kka2_1:4,P00552,1.32899,NO,80,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.144,-1.887,0.743,,0.358,E,B,0.44,-0.24,2.562,,63.64,HHH,-1.64633,0.168804,0.00488211,1.32899 kka2_1:2_M178R,kka2_1:2_178,Kka2,kka2_1:2,P00552,1.32906,NO,178,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-3.206,-1.763,-1.443,,0.554,.,b,0.55,0.68,3.152,,71.59,BHO,-2.154,0.295029,0.00717253,1.32906 kka2_1:2_V242F,kka2_1:2_242,Kka2,kka2_1:2,P00552,1.3291,NO,242,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-2.687,-4.427,1.74,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.295029,0.0102575,1.3291 kka2_1:2_A168L,kka2_1:2_168,Kka2,kka2_1:2,P00552,1.32937,NO,168,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.989,-3.651,1.662,,0.67,H,A,0.46,0.15,25.546,25.546,64.39,OHA,-2.12933,0.295029,0.00806773,1.32937 kka2_1:8_G234Q,kka2_1:8_234,Kka2,kka2_1:8,P00552,1.32938,NO,234,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-2.9,-2.619,-0.281,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.100394,0.00984449,1.32938 kka2_1:8_G234Q,kka2_1:8_234,Kka2,kka2_1:8,P00552,1.32938,NO,234,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-2.9,-2.619,-0.281,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.100394,0.00984449,1.32938 WW_domain_D194R,WW_domain_194,Yap65,WW_domain,P46937,1.32941,NO,194,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.536,-3.694,2.158,5.95614,,,,,,1.948,,74.4,HAP,-1.78933,0.153962,0.00483742,1.32941 kka2_1:2_F20Q,kka2_1:2_20,Kka2,kka2_1:2,P00552,1.32956,NO,20,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-3.354,-3.237,-0.117,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.295029,0.00701744,1.32956 kka2_1:2_E17K,kka2_1:2_17,Kka2,kka2_1:2,P00552,1.32961,NO,17,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.154,-2.831,0.677,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.295029,0.00688738,1.32961 beta-lactamase_0_G243Y,beta-lactamase_0_243,TEM-1,beta-lactamase_0,P62593,1.32967,NO,243,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.532,,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.0500837,0.00464034,1.32967 kka2_1:4_A176Q,kka2_1:4_176,Kka2,kka2_1:4,P00552,1.33,NO,176,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.621,-3.141,1.52,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.168804,0.0083587,1.33 kka2_1:4_F20C,kka2_1:4_20,Kka2,kka2_1:4,P00552,1.33009,NO,20,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-3.354,-5.001,1.647,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.168804,0.00701744,1.33009 kka2_1:4_A65V,kka2_1:4_65,Kka2,kka2_1:4,P00552,1.33018,NO,65,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-1.744,-2.657,0.913,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.168804,0.00709258,1.33018 kka2_1:2_Q4N,kka2_1:2_4,Kka2,kka2_1:2,P00552,1.33024,NO,4,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.361,-1.87,-0.491,,,,,,,2.026,,71.59,APA,-1.95533,0.295029,0.00239179,1.33024 kka2_1:2_G43R,kka2_1:2_43,Kka2,kka2_1:2,P00552,1.3307,NO,43,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.587,-2.733,1.146,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.295029,0.0071925,1.3307 kka2_1:4_E235I,kka2_1:4_235,Kka2,kka2_1:4,P00552,1.3307,NO,235,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.955,-4.019,2.064,,0.631,H,A,1.04,0.12,23.175,23.175,65.53,OAH,-2.07267,0.168804,0.0102806,1.3307 kka2_1:2_D52E,kka2_1:2_52,Kka2,kka2_1:2,P00552,1.33102,NO,52,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.271,-0.829,-1.442,,0.22,E,B,0.75,0.8,1.123,,71.59,PAH,-2.38367,0.295029,0.00175694,1.33102 kka2_1:4_V75T,kka2_1:4_75,Kka2,kka2_1:4,P00552,1.33107,NO,75,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-2.06,-2.915,0.855,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.168804,0.00693733,1.33107 kka2_1:4_V16A,kka2_1:4_16,Kka2,kka2_1:4,P00552,1.33121,NO,16,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-3.087,-2.407,-0.68,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.168804,0.00694011,1.33121 kka2_1:4_G151Q,kka2_1:4_151,Kka2,kka2_1:4,P00552,1.33144,NO,151,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.873,-4.048,3.175,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.168804,0.00339918,1.33144 kka2_1:2_R177D,kka2_1:2_177,Kka2,kka2_1:2,P00552,1.33165,NO,177,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.282,-3.754,1.472,,0.521,T,A,1.2,0.16,1.842,,63.64,HBH,-2.36967,0.295029,0.00768224,1.33165 kka2_1:4_A25D,kka2_1:4_25,Kka2,kka2_1:4,P00552,1.33201,NO,25,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.496,-2.743,0.247,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.168804,0.00595636,1.33201 kka2_1:4_T73C,kka2_1:4_73,Kka2,kka2_1:4,P00552,1.33242,NO,73,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.51,-3.584,1.074,,0.309,H,A,0.22,0.35,1.53,,56.06,PPO,-2.02333,0.168804,0.00628605,1.33242 kka2_1:4_L53R,kka2_1:4_53,Kka2,kka2_1:4,P00552,1.33247,NO,53,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-2.681,-2.891,0.21,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.168804,0.00671168,1.33247 kka2_1:2_V84A,kka2_1:2_84,Kka2,kka2_1:2,P00552,1.33252,NO,84,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-2.279,-1.994,-0.285,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.295029,0.00724019,1.33252 kka2_1:8_D238W,kka2_1:8_238,Kka2,kka2_1:8,P00552,1.33254,NO,238,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.83,-5.568,2.738,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.100394,0.0113863,1.33254 kka2_1:8_D238W,kka2_1:8_238,Kka2,kka2_1:8,P00552,1.33254,NO,238,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.83,-5.568,2.738,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.100394,0.0113863,1.33254 kka2_1:4_V46T,kka2_1:4_46,Kka2,kka2_1:4,P00552,1.33262,NO,46,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-2.62,-2.441,-0.179,,0.192,.,B,0.44,-1.12,9.564,,92.05,OHH,-1.88633,0.168804,0.00631301,1.33262 kka2_1:4_E199Q,kka2_1:4_199,Kka2,kka2_1:4,P00552,1.33267,NO,199,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.234,-3.039,0.805,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.168804,0.00854122,1.33267 kka2_1:2_Q155A,kka2_1:2_155,Kka2,kka2_1:2,P00552,1.33286,NO,155,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.606,-2.225,-0.381,,0.525,T,A,0.64,1.49,1.592,,63.64,APA,-1.726,0.295029,0.00641853,1.33286 kka2_1:4_A25N,kka2_1:4_25,Kka2,kka2_1:4,P00552,1.33286,NO,25,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.496,-3.071,0.575,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.168804,0.00595636,1.33286 kka2_1:4_A79K,kka2_1:4_79,Kka2,kka2_1:4,P00552,1.33286,NO,79,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.368,-2.882,0.514,,0.563,.,B,0.46,-0.43,2.291,,71.59,HHH,-1.752,0.168804,0.00664821,1.33286 kka2_1:4_R177D,kka2_1:4_177,Kka2,kka2_1:4,P00552,1.33299,NO,177,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.282,-3.754,1.472,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.168804,0.00768224,1.33299 kka2_1:8_A13G,kka2_1:8_13,Kka2,kka2_1:8,P00552,1.33299,NO,13,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.248,-2.748,0.5,,0.689,G,A,1.04,0.99,14.966,14.966,92.05,OHH,-1.646,0.100394,0.00784241,1.33299 kka2_1:8_A13G,kka2_1:8_13,Kka2,kka2_1:8,P00552,1.33299,NO,13,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.248,-2.748,0.5,,0.689,G,A,1.04,0.99,14.966,14.966,92.05,OHH,-1.646,0.100394,0.00784241,1.33299 kka2_1:8_R173A,kka2_1:8_173,Kka2,kka2_1:8,P00552,1.3331,NO,173,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.407,-2.391,-0.016,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.100394,0.00784999,1.3331 kka2_1:8_R173A,kka2_1:8_173,Kka2,kka2_1:8,P00552,1.3331,NO,173,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.407,-2.391,-0.016,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.100394,0.00784999,1.3331 kka2_1:4_D23I,kka2_1:4_23,Kka2,kka2_1:4,P00552,1.33312,NO,23,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.459,-4.001,1.542,,0.695,E,B,0.75,-0.65,2.416,,65.53,HAH,-1.94033,0.168804,0.007195,1.33312 kka2_1:8_S251M,kka2_1:8_251,Kka2,kka2_1:8,P00552,1.33332,NO,251,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.636,-4.807,2.171,,0.712,H,A,0.27,-0.25,,,71.59,APP,-2.09367,0.100394,0.0138916,1.33332 kka2_1:8_S251M,kka2_1:8_251,Kka2,kka2_1:8,P00552,1.33332,NO,251,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.636,-4.807,2.171,,0.712,H,A,0.27,-0.25,,,71.59,APP,-2.09367,0.100394,0.0138916,1.33332 kka2_1:2_D23H,kka2_1:2_23,Kka2,kka2_1:2,P00552,1.33341,NO,23,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.459,-3.07,0.611,,0.695,E,B,0.75,-0.65,18.207,18.207,65.53,HAH,-1.94033,0.295029,0.007195,1.33341 kka2_1:2_H106D,kka2_1:2_106,Kka2,kka2_1:2,P00552,1.33346,NO,106,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-3.13,-2.351,-0.779,,1.065,.,a,0.17,-0.95,2.53,,71.59,PBH,-2.10433,0.295029,0.00730778,1.33346 kka2_1:4_A56H,kka2_1:4_56,Kka2,kka2_1:4,P00552,1.33351,NO,56,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.083,-4.875,2.792,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.168804,0.00717715,1.33351 beta-lactamase_0_E210V,beta-lactamase_0_210,TEM-1,beta-lactamase_0,P62593,1.33372,NO,210,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.319,-1.881,-0.438,,0.476,H,A,1.04,0.75,3.618,,77.62,HAH,-1.88567,0.0500837,0.00663582,1.33372 kka2_1:4_G234R,kka2_1:4_234,Kka2,kka2_1:4,P00552,1.33405,NO,234,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-2.9,-3.848,0.948,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.168804,0.00984449,1.33405 kka2_1:4_E3W,kka2_1:4_3,Kka2,kka2_1:4,P00552,1.33424,NO,3,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.199,-4.936,2.737,,,,,,,7.22,,92.05,HAP,-2.11567,0.168804,0.00267607,1.33424 kka2_1:4_C209A,kka2_1:4_209,Kka2,kka2_1:4,P00552,1.33425,NO,209,C,A,CA,Special,Hydrophobic,5.07,6,0.93,195,121,89,-32,108.5,88.6,-19.9,-0.906,-2.925,2.019,,,.,a,0.46,-0.89,0.267,,19.32,AOO,-0.903,0.168804,0.00260862,1.33425 kka2_1:4_E199H,kka2_1:4_199,Kka2,kka2_1:4,P00552,1.33428,NO,199,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.234,-3.025,0.791,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.168804,0.00854122,1.33428 kka2_1:4_D5E,kka2_1:4_5,Kka2,kka2_1:4,P00552,1.33435,NO,5,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-1.306,-1.813,0.507,,,,,,,,,71.59,PAO,-1.784,0.168804,0.00222864,1.33435 kka2_1:4_S68N,kka2_1:4_68,Kka2,kka2_1:4,P00552,1.33435,NO,68,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.623,-3.062,0.439,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.168804,0.00608265,1.33435 kka2_1:4_V83F,kka2_1:4_83,Kka2,kka2_1:4,P00552,1.33451,NO,83,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-2.567,-2.568,0.001,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.168804,0.00650486,1.33451 kka2_1:4_V75L,kka2_1:4_75,Kka2,kka2_1:4,P00552,1.33458,NO,75,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-2.06,-1.581,-0.479,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.168804,0.00693733,1.33458 kka2_1:4_A137L,kka2_1:4_137,Kka2,kka2_1:4,P00552,1.33477,NO,137,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.156,-1.375,-0.781,,0.029,H,A,0.46,0.34,2.227,,63.26,PHB,-2.559,0.168804,0.00515054,1.33477 kka2_1:4_F20S,kka2_1:4_20,Kka2,kka2_1:4,P00552,1.335,NO,20,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-3.354,-2.147,-1.207,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.168804,0.00701744,1.335 kka2_1:4_Q252Y,kka2_1:4_252,Kka2,kka2_1:4,P00552,1.33509,NO,252,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.63,-4.393,1.763,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.168804,0.0121001,1.33509 kka2_1:4_V242I,kka2_1:4_242,Kka2,kka2_1:4,P00552,1.33509,NO,242,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-2.687,-3.231,0.544,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.168804,0.0102575,1.33509 beta-lactamase_0_A148F,beta-lactamase_0_148,TEM-1,beta-lactamase_0,P62593,1.33512,NO,148,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.757,-4.389,2.632,,0.379,H,A,0.46,-0.55,19.42,19.42,72.73,PHH,-1.40167,0.0500837,0.00547053,1.33512 kka2_1:4_T225V,kka2_1:4_225,Kka2,kka2_1:4,P00552,1.33519,NO,225,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.393,-2.516,0.123,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.168804,0.0113598,1.33519 kka2_1:8_G6M,kka2_1:8_6,Kka2,kka2_1:8,P00552,1.33524,NO,6,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.685,-4.549,2.864,,,,,,,,,71.59,AOH,-1.639,0.100394,0.00204693,1.33524 kka2_1:8_G6M,kka2_1:8_6,Kka2,kka2_1:8,P00552,1.33524,NO,6,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.685,-4.549,2.864,,,,,,,,,71.59,AOH,-1.639,0.100394,0.00204693,1.33524 kka2_1:4_A247P,kka2_1:4_247,Kka2,kka2_1:4,P00552,1.33529,NO,247,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.459,-2.362,-0.097,,1.01,S,A,0.46,0.65,,,92.05,HHH,-2.197,0.168804,0.0102428,1.33529 kka2_1:8_V242K,kka2_1:8_242,Kka2,kka2_1:8,P00552,1.33545,NO,242,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-2.687,-2.489,-0.198,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.100394,0.0102575,1.33545 kka2_1:8_V242K,kka2_1:8_242,Kka2,kka2_1:8,P00552,1.33545,NO,242,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-2.687,-2.489,-0.198,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.100394,0.0102575,1.33545 beta-lactamase_0_V106C,beta-lactamase_0_106,TEM-1,beta-lactamase_0,P62593,1.33546,NO,106,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.218,-4.774,3.556,,0.258,T,A,0.44,0.24,0.952,,72.73,OHP,-1.04933,0.0500837,0.00304168,1.33546 beta-lactamase_0_T158D,beta-lactamase_0_158,TEM-1,beta-lactamase_0,P62593,1.33549,NO,158,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.116,-3.478,2.362,,0.036,,B,0.22,-0.85,1.041,,69.58,HPB,-1.269,0.0500837,0.00341825,1.33549 kka2_1:4_G43Y,kka2_1:4_43,Kka2,kka2_1:4,P00552,1.33552,NO,43,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.587,-3.332,1.745,,0.862,T,l,0.75,-0.67,2.247,,63.26,POB,-2.18533,0.168804,0.0071925,1.33552 kka2_1:4_A137M,kka2_1:4_137,Kka2,kka2_1:4,P00552,1.3359,NO,137,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.156,-4.232,2.076,,0.029,H,A,0.46,0.34,2.227,,63.26,PHB,-2.559,0.168804,0.00515054,1.3359 kka2_1:8_Q155S,kka2_1:8_155,Kka2,kka2_1:8,P00552,1.33595,NO,155,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.606,-3.295,0.689,,0.525,T,A,0.64,1.49,,,63.64,APA,-1.726,0.100394,0.00641853,1.33595 kka2_1:8_Q155S,kka2_1:8_155,Kka2,kka2_1:8,P00552,1.33595,NO,155,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.606,-3.295,0.689,,0.525,T,A,0.64,1.49,,,63.64,APA,-1.726,0.100394,0.00641853,1.33595 kka2_1:4_L165F,kka2_1:4_165,Kka2,kka2_1:4,P00552,1.33604,NO,165,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-2.453,-4.3,1.847,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.168804,0.00801161,1.33604 kka2_1:4_Q163R,kka2_1:4_163,Kka2,kka2_1:4,P00552,1.33624,NO,163,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-2.162,-2.527,0.365,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.168804,0.00719507,1.33624 kka2_1:4_G6R,kka2_1:4_6,Kka2,kka2_1:4,P00552,1.33629,NO,6,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.685,-3.575,1.89,,,,,,,,,71.59,AOH,-1.639,0.168804,0.00204693,1.33629 beta-lactamase_0_L284D,beta-lactamase_0_284,TEM-1,beta-lactamase_0,P62593,1.33648,NO,284,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.981,,,,0.848,H,A,2.89,0.67,4.544,,77.62,PHH,-1.82133,0.0500837,0.0686156,1.33648 kka2_1:4_S40C,kka2_1:4_40,Kka2,kka2_1:4,P00552,1.33657,NO,40,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.645,-3.648,1.003,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.168804,0.00693477,1.33657 kka2_1:4_R177G,kka2_1:4_177,Kka2,kka2_1:4,P00552,1.33666,NO,177,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-2.282,-2.48,0.198,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.168804,0.00768224,1.33666 kka2_1:4_V83Q,kka2_1:4_83,Kka2,kka2_1:4,P00552,1.33688,NO,83,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-2.567,-3.072,0.505,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.168804,0.00650486,1.33688 kka2_1:4_S251L,kka2_1:4_251,Kka2,kka2_1:4,P00552,1.33692,NO,251,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.636,-2.87,0.234,,0.712,H,A,0.77,-0.25,,,71.59,APP,-2.09367,0.168804,0.0138916,1.33692 kka2_1:4_Q252E,kka2_1:4_252,Kka2,kka2_1:4,P00552,1.33732,NO,252,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.63,-1.971,-0.659,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.168804,0.0121001,1.33732 kka2_1:8_Q155V,kka2_1:8_155,Kka2,kka2_1:8,P00552,1.33736,NO,155,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.606,-2.82,0.214,,0.525,T,A,0.64,1.49,,,63.64,APA,-1.726,0.100394,0.00641853,1.33736 kka2_1:8_Q155V,kka2_1:8_155,Kka2,kka2_1:8,P00552,1.33736,NO,155,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.606,-2.82,0.214,,0.525,T,A,0.64,1.49,,,63.64,APA,-1.726,0.100394,0.00641853,1.33736 kka2_1:8_S251N,kka2_1:8_251,Kka2,kka2_1:8,P00552,1.33758,NO,251,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.636,-3.845,1.209,,0.712,H,A,0.27,-0.25,,,71.59,APP,-2.09367,0.100394,0.0138916,1.33758 kka2_1:8_S251N,kka2_1:8_251,Kka2,kka2_1:8,P00552,1.33758,NO,251,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.636,-3.845,1.209,,0.712,H,A,0.27,-0.25,,,71.59,APP,-2.09367,0.100394,0.0138916,1.33758 kka2_1:2_D33Q,kka2_1:2_33,Kka2,kka2_1:2,P00552,1.33785,NO,33,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.186,-3.005,0.819,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.295029,0.00633568,1.33785 kka2_1:4_R173A,kka2_1:4_173,Kka2,kka2_1:4,P00552,1.33786,NO,173,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.407,-2.391,-0.016,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.168804,0.00784999,1.33786 kka2_1:8_A247K,kka2_1:8_247,Kka2,kka2_1:8,P00552,1.33793,NO,247,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.459,-3.008,0.549,,1.01,S,A,0.46,0.65,18.904,18.904,92.05,HHH,-2.197,0.100394,0.0102428,1.33793 kka2_1:8_A247K,kka2_1:8_247,Kka2,kka2_1:8,P00552,1.33793,NO,247,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.459,-3.008,0.549,,1.01,S,A,0.46,0.65,18.904,18.904,92.05,HHH,-2.197,0.100394,0.0102428,1.33793 kka2_1:4_A9M,kka2_1:4_9,Kka2,kka2_1:4,P00552,1.338,NO,9,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.079,-2.864,0.785,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.168804,0.00273264,1.338 kka2_1:4_E199N,kka2_1:4_199,Kka2,kka2_1:4,P00552,1.33807,NO,199,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.234,-3.807,1.573,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.168804,0.00854122,1.33807 beta-lactamase_0_M127E,beta-lactamase_0_127,TEM-1,beta-lactamase_0,P62593,1.33827,NO,127,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-2.251,-3.04,0.789,,0.312,S,A,0.55,0.32,9.35,9.35,72.73,PHP,-1.40433,0.0500837,0.00437927,1.33827 kka2_1:8_L47K,kka2_1:8_47,Kka2,kka2_1:8,P00552,1.33831,NO,47,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.265,-3.649,2.384,,0.139,E,B,1.59,-0.86,5.086,,63.26,HHH,-1.77933,0.100394,0.00509386,1.33831 kka2_1:8_L47K,kka2_1:8_47,Kka2,kka2_1:8,P00552,1.33831,NO,47,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.265,-3.649,2.384,,0.139,E,B,1.59,-0.86,5.086,,63.26,HHH,-1.77933,0.100394,0.00509386,1.33831 kka2_1:2_D238L,kka2_1:2_238,Kka2,kka2_1:2,P00552,1.33833,NO,238,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.83,-3.612,0.782,,0.604,H,A,0.75,-0.33,22.789,22.789,92.05,HAB,-2.633,0.295029,0.0113863,1.33833 kka2_1:2_V242M,kka2_1:2_242,Kka2,kka2_1:2,P00552,1.33838,NO,242,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-2.687,-4.779,2.092,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.295029,0.0102575,1.33838 kka2_1:8_E149V,kka2_1:8_149,Kka2,kka2_1:8,P00552,1.33839,NO,149,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.994,-3.648,1.654,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.100394,0.00803343,1.33839 kka2_1:8_E149V,kka2_1:8_149,Kka2,kka2_1:8,P00552,1.33839,NO,149,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.994,-3.648,1.654,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.100394,0.00803343,1.33839 kka2_1:2_L47H,kka2_1:2_47,Kka2,kka2_1:2,P00552,1.33846,NO,47,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.265,-4.833,3.568,,0.139,E,B,0.55,-0.86,2.369,,63.26,HHH,-1.77933,0.295029,0.00509386,1.33846 kka2_1:4_R177F,kka2_1:4_177,Kka2,kka2_1:4,P00552,1.3385,NO,177,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.282,-4.359,2.077,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.168804,0.00768224,1.3385 kka2_1:4_Q42K,kka2_1:4_42,Kka2,kka2_1:4,P00552,1.33882,NO,42,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.907,-2.899,-0.008,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.168804,0.00679212,1.33882 beta-lactamase_0_T116A,beta-lactamase_0_116,TEM-1,beta-lactamase_0,P62593,1.33899,NO,116,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.28,-2.469,1.189,,0.115,E,B,0.22,-0.12,1.356,,67.48,HPH,-1.39967,0.0500837,0.00336175,1.33899 kka2_1:4_A56G,kka2_1:4_56,Kka2,kka2_1:4,P00552,1.33915,NO,56,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.083,-2.527,0.444,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.168804,0.00717715,1.33915 beta-lactamase_0_V214K,beta-lactamase_0_214,TEM-1,beta-lactamase_0,P62593,1.33927,NO,214,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.299,-3.699,2.4,,0.375,S,A,0.44,-0.44,3.712,,74.48,BHH,-1.53733,0.0500837,0.00628442,1.33927 kka2_1:4_V16Q,kka2_1:4_16,Kka2,kka2_1:4,P00552,1.3394,NO,16,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-3.087,-2.664,-0.423,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.168804,0.00694011,1.3394 kka2_1:4_L47Q,kka2_1:4_47,Kka2,kka2_1:4,P00552,1.33976,NO,47,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.265,-2.824,1.559,,0.139,E,B,0.55,-0.86,2.369,,63.26,HHH,-1.77933,0.168804,0.00509386,1.33976 kka2_1:4_E149Y,kka2_1:4_149,Kka2,kka2_1:4,P00552,1.33979,NO,149,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.994,-4.359,2.365,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.168804,0.00803343,1.33979 kka2_1:2_G234S,kka2_1:2_234,Kka2,kka2_1:2,P00552,1.33985,NO,234,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-2.9,-2.468,-0.432,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.295029,0.00984449,1.33985 kka2_1:4_H8K,kka2_1:4_8,Kka2,kka2_1:4,P00552,1.34,NO,8,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-2.759,-3.463,0.704,,,,,,,,,71.59,HBH,-2.25467,0.168804,0.00256422,1.34 kka2_1:4_S105A,kka2_1:4_105,Kka2,kka2_1:4,P00552,1.34052,NO,105,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-1.945,-1.746,-0.199,,0.056,S,B,0.77,-1.04,3.442,,65.53,PPB,-2.17033,0.168804,0.00847233,1.34052 kka2_1:4_A255G,kka2_1:4_255,Kka2,kka2_1:4,P00552,1.34054,NO,255,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.715,-2.509,0.794,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.168804,0.0126809,1.34054 kka2_1:4_S11Q,kka2_1:4_11,Kka2,kka2_1:4,P00552,1.34061,NO,11,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.322,-3.989,1.667,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.168804,0.00381691,1.34061 beta-lactamase_0_D231M,beta-lactamase_0_231,TEM-1,beta-lactamase_0,P62593,1.34068,NO,231,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.816,-4.927,4.111,,,E,B,0.75,-1.06,4.975,,65.38,HAB,-0.994,0.0500837,0.00107395,1.34068 kka2_1:4_A35T,kka2_1:4_35,Kka2,kka2_1:4,P00552,1.34068,NO,35,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.127,-2.654,0.527,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.168804,0.00630016,1.34068 kka2_1:4_A13Q,kka2_1:4_13,Kka2,kka2_1:4,P00552,1.34081,NO,13,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.248,-3.029,0.781,,0.689,G,A,0.46,0.99,,,92.05,OHH,-1.646,0.168804,0.00784241,1.34081 kka2_1:2_R177Q,kka2_1:2_177,Kka2,kka2_1:2,P00552,1.34083,NO,177,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.282,-3.061,0.779,,0.521,T,A,1.2,0.16,1.842,,63.64,HBH,-2.36967,0.295029,0.00768224,1.34083 kka2_1:4_G234A,kka2_1:4_234,Kka2,kka2_1:4,P00552,1.34117,NO,234,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-2.9,-2.255,-0.645,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.168804,0.00984449,1.34117 kka2_1:4_I29T,kka2_1:4_29,Kka2,kka2_1:4,P00552,1.34138,NO,29,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.692,-2.952,1.26,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.168804,0.00619521,1.34138 kka2_1:2_D33N,kka2_1:2_33,Kka2,kka2_1:2,P00552,1.34152,NO,33,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.186,-2.693,0.507,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.295029,0.00633568,1.34152 kka2_1:4_A41N,kka2_1:4_41,Kka2,kka2_1:4,P00552,1.34156,NO,41,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.879,-3.231,1.352,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.168804,0.00543332,1.34156 kka2_1:4_R177T,kka2_1:4_177,Kka2,kka2_1:4,P00552,1.34184,NO,177,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-2.282,-2.275,-0.007,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.168804,0.00768224,1.34184 kka2_1:2_D23N,kka2_1:2_23,Kka2,kka2_1:2,P00552,1.34203,NO,23,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.459,-3.82,1.361,,0.695,E,B,0.75,-0.65,18.207,18.207,65.53,HAH,-1.94033,0.295029,0.007195,1.34203 kka2_1:2_A172E,kka2_1:2_172,Kka2,kka2_1:2,P00552,1.34208,NO,172,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.757,-2.527,0.77,,0.495,H,A,0.46,-0.44,0.362,,65.53,HHB,-1.83,0.295029,0.0079265,1.34208 kka2_1:4_D5V,kka2_1:4_5,Kka2,kka2_1:4,P00552,1.34223,NO,5,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.306,-3.484,2.178,,,,,,,,,71.59,PAO,-1.784,0.168804,0.00222864,1.34223 kka2_1:4_T146M,kka2_1:4_146,Kka2,kka2_1:4,P00552,1.34227,NO,146,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.978,-3.5,0.522,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.168804,0.00606474,1.34227 kka2_1:2_Q136S,kka2_1:2_136,Kka2,kka2_1:2,P00552,1.34233,NO,136,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-3.021,-2.294,-0.727,,0.331,,b,0.4,0.96,2.726,,92.05,BPH,-2.16933,0.295029,0.00624149,1.34233 kka2_1:4_Q163L,kka2_1:4_163,Kka2,kka2_1:4,P00552,1.34249,NO,163,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.162,-1.74,-0.422,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.168804,0.00719507,1.34249 kka2_1:2_W91Y,kka2_1:2_91,Kka2,kka2_1:2,P00552,1.34267,NO,91,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,-1.178,-2.672,1.494,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.295029,0.00358653,1.34267 kka2_1:4_L165E,kka2_1:4_165,Kka2,kka2_1:4,P00552,1.34297,NO,165,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-2.453,-2.802,0.349,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.168804,0.00801161,1.34297 kka2_1:2_A168Q,kka2_1:2_168,Kka2,kka2_1:2,P00552,1.34306,NO,168,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.989,-2.544,0.555,,0.67,H,A,0.46,0.15,25.546,25.546,64.39,OHA,-2.12933,0.295029,0.00806773,1.34306 kka2_1:4_R177C,kka2_1:4_177,Kka2,kka2_1:4,P00552,1.34314,NO,177,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.282,-5.144,2.862,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.168804,0.00768224,1.34314 kka2_1:2_P45N,kka2_1:2_45,Kka2,kka2_1:2,P00552,1.34326,NO,45,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.774,-3.854,2.08,,0.669,,B,0.52,-0.76,4.882,,71.59,BOH,-2.152,0.295029,0.00590481,1.34326 kka2_1:2_G234T,kka2_1:2_234,Kka2,kka2_1:2,P00552,1.34331,NO,234,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-2.9,-3.606,0.706,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.295029,0.00984449,1.34331 kka2_1:4_L7K,kka2_1:4_7,Kka2,kka2_1:4,P00552,1.3439,NO,7,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.926,-3.481,1.555,,,,,,,3.012,,71.59,OHB,-2.12333,0.168804,0.00269456,1.3439 kka2_1:4_E161P,kka2_1:4_161,Kka2,kka2_1:4,P00552,1.34406,NO,161,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.581,-2.997,1.416,,0.829,G,A,1.52,2.24,1.612,,92.05,AAB,-1.861,0.168804,0.00760103,1.34406 kka2_1:4_M178C,kka2_1:4_178,Kka2,kka2_1:4,P00552,1.34408,NO,178,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-3.206,-3.246,0.04,,0.554,.,b,0.55,0.68,9.913,9.913,71.59,BHO,-2.154,0.168804,0.00717253,1.34408 beta-lactamase_0_F58W,beta-lactamase_0_58,TEM-1,beta-lactamase_0,P62593,1.34428,NO,58,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-2.914,-2.275,-0.639,,0.266,E,B,0.58,-0.07,24.637,24.637,77.62,PHB,-2.059,0.0500837,0.00523369,1.34428 kka2_1:4_G234E,kka2_1:4_234,Kka2,kka2_1:4,P00552,1.34466,NO,234,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-2.9,-1.763,-1.137,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.168804,0.00984449,1.34466 kka2_1:2_H139F,kka2_1:2_139,Kka2,kka2_1:2,P00552,1.34483,NO,139,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-2.809,-3.506,0.697,,0.471,H,A,0.87,0.68,13.912,13.912,63.64,BBB,-2.22,0.295029,0.00734779,1.34483 kka2_1:4_A9L,kka2_1:4_9,Kka2,kka2_1:4,P00552,1.34492,NO,9,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.079,-2.291,0.212,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.168804,0.00273264,1.34492 kka2_1:8_L243Q,kka2_1:8_243,Kka2,kka2_1:8,P00552,1.34493,NO,243,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-2.651,-2.876,0.225,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.100394,0.00884927,1.34493 kka2_1:8_L243Q,kka2_1:8_243,Kka2,kka2_1:8,P00552,1.34493,NO,243,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-2.651,-2.876,0.225,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.100394,0.00884927,1.34493 kka2_1:2_V16H,kka2_1:2_16,Kka2,kka2_1:2,P00552,1.34516,NO,16,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-3.087,-3.512,0.425,,0.742,T,A,0.44,0.34,1.746,,71.59,HHA,-2.211,0.295029,0.00694011,1.34516 kka2_1:4_Q61P,kka2_1:4_61,Kka2,kka2_1:4,P00552,1.34569,NO,61,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.982,-1.818,-1.164,,0.591,H,A,0.64,0.41,3.484,,65.53,HPA,-1.85667,0.168804,0.00612092,1.34569 kka2_1:4_A166H,kka2_1:4_166,Kka2,kka2_1:4,P00552,1.34573,NO,166,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.407,-4.764,2.357,,0.534,.,B,0.46,1.03,,,71.59,HHO,-2.421,0.168804,0.00799912,1.34573 kka2_1:2_E199A,kka2_1:2_199,Kka2,kka2_1:2,P00552,1.34589,NO,199,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.234,-2.101,-0.133,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.295029,0.00854122,1.34589 beta-lactamase_0_P65M,beta-lactamase_0_65,TEM-1,beta-lactamase_0,P62593,1.34605,NO,65,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.894,-4.494,3.6,,0.098,E,B,0.52,-0.62,0.663,,40.56,HOH,-1.03233,0.0500837,0.00152776,1.34605 kka2_1:2_S251K,kka2_1:2_251,Kka2,kka2_1:2,P00552,1.34627,NO,251,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.636,-3.007,0.371,,0.712,H,A,0.27,-0.25,32.832,32.832,71.59,APP,-2.09367,0.295029,0.0138916,1.34627 kka2_1:4_A110M,kka2_1:4_110,Kka2,kka2_1:4,P00552,1.34644,NO,110,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.064,-3.65,1.586,,0.175,H,A,0.46,-1.19,23.237,23.237,71.59,OHA,-1.91867,0.168804,0.00759851,1.34644 kka2_1:2_L47K,kka2_1:2_47,Kka2,kka2_1:2,P00552,1.34649,NO,47,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.265,-3.649,2.384,,0.139,E,B,0.55,-0.86,2.369,,63.26,HHH,-1.77933,0.295029,0.00509386,1.34649 beta-lactamase_0_F149M,beta-lactamase_0_149,TEM-1,beta-lactamase_0,P62593,1.34681,NO,149,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.299,-4.454,3.155,,0.195,H,A,0.58,0.11,3.518,,63.99,HHH,-1.46067,0.0500837,0.00418462,1.34681 kka2_1:4_V16E,kka2_1:4_16,Kka2,kka2_1:4,P00552,1.34688,NO,16,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-3.087,-2.983,-0.104,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.168804,0.00694011,1.34688 kka2_1:4_L7C,kka2_1:4_7,Kka2,kka2_1:4,P00552,1.3469,NO,7,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.926,-4.785,2.859,,,,,,,3.012,,71.59,OHB,-2.12333,0.168804,0.00269456,1.3469 beta-lactamase_0_K30A,beta-lactamase_0_30,TEM-1,beta-lactamase_0,P62593,1.34697,NO,30,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-2.307,-2.101,-0.206,,0.142,H,A,2.34,-0.65,1.491,,93.01,HBH,-2.32833,0.0500837,0.00448593,1.34697 kka2_1:4_A25T,kka2_1:4_25,Kka2,kka2_1:4,P00552,1.3472,NO,25,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.496,-2.626,0.13,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.168804,0.00595636,1.3472 kka2_1:2_E149N,kka2_1:2_149,Kka2,kka2_1:2,P00552,1.34723,NO,149,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.994,-2.918,0.924,,0.674,H,A,1.04,1.63,15.361,15.361,71.59,HAH,-1.59667,0.295029,0.00803343,1.34723 kka2_1:2_A108T,kka2_1:2_108,Kka2,kka2_1:2,P00552,1.34726,NO,108,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.061,-2.374,0.313,,0.243,.,B,0.46,-1.34,2.462,,71.59,HHO,-1.57033,0.295029,0.00751209,1.34726 kka2_1:4_H106D,kka2_1:4_106,Kka2,kka2_1:4,P00552,1.34729,NO,106,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-3.13,-2.351,-0.779,,1.065,.,a,0.17,-0.95,16.74,16.74,71.59,PBH,-2.10433,0.168804,0.00730778,1.34729 kka2_1:2_G234E,kka2_1:2_234,Kka2,kka2_1:2,P00552,1.34739,NO,234,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-2.9,-1.763,-1.137,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.295029,0.00984449,1.34739 kka2_1:2_A137R,kka2_1:2_137,Kka2,kka2_1:2,P00552,1.34754,NO,137,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.156,-3.088,0.932,,0.029,H,A,0.46,0.34,1.323,,63.26,PHB,-2.559,0.295029,0.00515054,1.34754 kka2_1:4_V46C,kka2_1:4_46,Kka2,kka2_1:4,P00552,1.3476,NO,46,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-2.62,-3.346,0.726,,0.192,.,B,0.44,-1.12,9.564,,92.05,OHH,-1.88633,0.168804,0.00631301,1.3476 beta-lactamase_0_V214T,beta-lactamase_0_214,TEM-1,beta-lactamase_0,P62593,1.34769,NO,214,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.299,-1.73,0.431,,0.375,S,A,0.44,-0.44,3.712,,74.48,BHH,-1.53733,0.0500837,0.00628442,1.34769 kka2_1:4_V242E,kka2_1:4_242,Kka2,kka2_1:4,P00552,1.34781,NO,242,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-2.687,-2.323,-0.364,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.168804,0.0102575,1.34781 kka2_1:4_A14L,kka2_1:4_14,Kka2,kka2_1:4,P00552,1.34789,NO,14,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.837,-3.498,1.661,,0.728,G,A,0.46,0.7,0.36,,71.59,HHH,-1.82567,0.168804,0.00706614,1.34789 kka2_1:2_A168T,kka2_1:2_168,Kka2,kka2_1:2,P00552,1.34793,NO,168,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-1.989,-2.711,0.722,,0.67,H,A,0.46,0.15,25.546,25.546,64.39,OHA,-2.12933,0.295029,0.00806773,1.34793 kka2_1:2_A25V,kka2_1:2_25,Kka2,kka2_1:2,P00552,1.348,NO,25,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.496,-2.849,0.353,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.295029,0.00595636,1.348 kka2_1:2_G234Y,kka2_1:2_234,Kka2,kka2_1:2,P00552,1.34819,NO,234,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-2.9,-4.454,1.554,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.295029,0.00984449,1.34819 kka2_1:4_Q4F,kka2_1:4_4,Kka2,kka2_1:4,P00552,1.34834,NO,4,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.361,-4.126,1.765,,,,,,,2.026,,71.59,APA,-1.95533,0.168804,0.00239179,1.34834 kka2_1:4_D5L,kka2_1:4_5,Kka2,kka2_1:4,P00552,1.34835,NO,5,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.306,-3.538,2.232,,,,,,,,,71.59,PAO,-1.784,0.168804,0.00222864,1.34835 kka2_1:4_V46G,kka2_1:4_46,Kka2,kka2_1:4,P00552,1.34854,NO,46,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-2.62,-2.793,0.173,,0.192,.,B,0.44,-1.12,9.564,,92.05,OHH,-1.88633,0.168804,0.00631301,1.34854 kka2_1:4_R18F,kka2_1:4_18,Kka2,kka2_1:4,P00552,1.34858,NO,18,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.055,-3.418,1.363,,0.474,T,A,1.2,0.54,8.405,8.405,71.59,ABH,-1.821,0.168804,0.00724065,1.34858 kka2_1:2_L53V,kka2_1:2_53,Kka2,kka2_1:2,P00552,1.34879,NO,53,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-2.681,-2.592,-0.089,,0.569,E,B,0.55,0.8,19.536,19.536,71.59,AHP,-2.47433,0.295029,0.00671168,1.34879 kka2_1:2_P249K,kka2_1:2_249,Kka2,kka2_1:2,P00552,1.34902,NO,249,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.867,-3.802,1.935,,0.406,.,B,0.52,-0.01,0.76,,92.05,HOA,-1.66867,0.295029,0.011045,1.34902 kka2_1:2_F20H,kka2_1:2_20,Kka2,kka2_1:2,P00552,1.3491,NO,20,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-3.354,-4.805,1.451,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.295029,0.00701744,1.3491 beta-lactamase_0_E61I,beta-lactamase_0_61,TEM-1,beta-lactamase_0,P62593,1.34927,NO,61,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.115,-4.14,2.025,,0.775,T,a,1.04,1.29,34.763,34.763,77.62,OAA,-1.92567,0.0500837,0.00440955,1.34927 kka2_1:4_A137C,kka2_1:4_137,Kka2,kka2_1:4,P00552,1.34931,NO,137,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.156,-4.817,2.661,,0.029,H,A,0.46,0.34,2.227,,63.26,PHB,-2.559,0.168804,0.00515054,1.34931 kka2_1:2_V83Y,kka2_1:2_83,Kka2,kka2_1:2,P00552,1.34939,NO,83,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-2.567,-3.301,0.734,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.295029,0.00650486,1.34939 kka2_1:4_S11T,kka2_1:4_11,Kka2,kka2_1:4,P00552,1.34943,NO,11,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.322,-3.33,1.008,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.168804,0.00381691,1.34943 kka2_1:4_T73V,kka2_1:4_73,Kka2,kka2_1:4,P00552,1.34979,NO,73,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.51,-2.513,0.003,,0.309,H,A,0.22,0.35,1.53,,56.06,PPO,-2.02333,0.168804,0.00628605,1.34979 kka2_1:4_R239V,kka2_1:4_239,Kka2,kka2_1:4,P00552,1.34996,NO,239,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.949,-2.967,0.018,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.168804,0.00835326,1.34996 kka2_1:4_L81K,kka2_1:4_81,Kka2,kka2_1:4,P00552,1.35008,NO,81,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.427,-3.851,2.424,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.168804,0.00805839,1.35008 kka2_1:4_L103A,kka2_1:4_103,Kka2,kka2_1:4,P00552,1.3501,NO,103,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-2.362,-1.403,-0.959,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.168804,0.00574792,1.3501 kka2_1:2_A137L,kka2_1:2_137,Kka2,kka2_1:2,P00552,1.35011,NO,137,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.156,-1.375,-0.781,,0.029,H,A,0.46,0.34,1.323,,63.26,PHB,-2.559,0.295029,0.00515054,1.35011 kka2_1:2_L53I,kka2_1:2_53,Kka2,kka2_1:2,P00552,1.35025,NO,53,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-2.681,-2.859,0.178,,0.569,E,B,0.55,0.8,19.536,19.536,71.59,AHP,-2.47433,0.295029,0.00671168,1.35025 kka2_1:2_D52G,kka2_1:2_52,Kka2,kka2_1:2,P00552,1.35031,NO,52,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.271,-3.385,1.114,,0.22,E,B,0.75,0.8,1.123,,71.59,PAH,-2.38367,0.295029,0.00175694,1.35031 kka2_1:2_H8G,kka2_1:2_8,Kka2,kka2_1:2,P00552,1.35032,NO,8,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-2.759,-2.248,-0.511,,,,,,,,,71.59,HBH,-2.25467,0.295029,0.00256422,1.35032 kka2_1:4_V242A,kka2_1:4_242,Kka2,kka2_1:4,P00552,1.35044,NO,242,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-2.687,-2.142,-0.545,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.168804,0.0102575,1.35044 kka2_1:2_S40Q,kka2_1:2_40,Kka2,kka2_1:2,P00552,1.35055,NO,40,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.645,-2.827,0.182,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.295029,0.00693477,1.35055 kka2_1:4_S251F,kka2_1:4_251,Kka2,kka2_1:4,P00552,1.35077,NO,251,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.636,-4.475,1.839,,0.712,H,A,0.77,-0.25,,,71.59,APP,-2.09367,0.168804,0.0138916,1.35077 beta-lactamase_0_I140F,beta-lactamase_0_140,TEM-1,beta-lactamase_0,P62593,1.35079,NO,140,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.733,-2.91,1.177,,0.128,H,A,0.48,0.41,4.714,,73.08,PHO,-1.48733,0.0500837,0.00597777,1.35079 kka2_1:2_E161P,kka2_1:2_161,Kka2,kka2_1:2,P00552,1.35079,NO,161,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.581,-2.997,1.416,,0.829,G,A,1.52,2.24,1.612,,92.05,AAB,-1.861,0.295029,0.00760103,1.35079 kka2_1:4_M178Y,kka2_1:4_178,Kka2,kka2_1:4,P00552,1.3508,NO,178,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-3.206,-4.367,1.161,,0.554,.,b,0.55,0.68,9.913,9.913,71.59,BHO,-2.154,0.168804,0.00717253,1.3508 kka2_1:4_P45E,kka2_1:4_45,Kka2,kka2_1:4,P00552,1.35083,NO,45,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.774,-2.616,0.842,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.168804,0.00590481,1.35083 beta-lactamase_0_E62M,beta-lactamase_0_62,TEM-1,beta-lactamase_0,P62593,1.35084,NO,62,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.193,-4.77,3.577,,0.342,S,B,1.04,-0.3,5.784,,73.08,AAB,-1.417,0.0500837,0.00264802,1.35084 kka2_1:2_S40T,kka2_1:2_40,Kka2,kka2_1:2,P00552,1.3512,NO,40,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.645,-2.259,-0.386,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.295029,0.00693477,1.3512 kka2_1:2_R177K,kka2_1:2_177,Kka2,kka2_1:2,P00552,1.35135,NO,177,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.282,-3.03,0.748,,0.521,T,A,1.2,0.16,1.842,,63.64,HBH,-2.36967,0.295029,0.00768224,1.35135 kka2_1:2_K175C,kka2_1:2_175,Kka2,kka2_1:2,P00552,1.35137,NO,175,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-2.897,-2.882,-0.015,,0.579,H,A,1.3,0.51,15.629,15.629,71.59,HBH,-1.82333,0.295029,0.00693093,1.35137 kka2_1:4_A13T,kka2_1:4_13,Kka2,kka2_1:4,P00552,1.35142,NO,13,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.248,-2.994,0.746,,0.689,G,A,0.46,0.99,,,92.05,OHH,-1.646,0.168804,0.00784241,1.35142 kka2_1:2_L243Q,kka2_1:2_243,Kka2,kka2_1:2,P00552,1.35152,NO,243,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-2.651,-2.876,0.225,,0.277,H,A,1.59,-0.67,13.165,13.165,92.05,HHH,-2.03767,0.295029,0.00884927,1.35152 kka2_1:2_D52C,kka2_1:2_52,Kka2,kka2_1:2,P00552,1.35163,NO,52,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.271,-5.339,3.068,,0.22,E,B,0.75,0.8,1.123,,71.59,PAH,-2.38367,0.295029,0.00175694,1.35163 kka2_1:8_Q163V,kka2_1:8_163,Kka2,kka2_1:8,P00552,1.35164,NO,163,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.162,-2.687,0.525,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.100394,0.00719507,1.35164 kka2_1:8_Q163V,kka2_1:8_163,Kka2,kka2_1:8,P00552,1.35164,NO,163,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.162,-2.687,0.525,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.100394,0.00719507,1.35164 kka2_1:4_A9W,kka2_1:4_9,Kka2,kka2_1:4,P00552,1.35178,NO,9,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.079,-5.293,3.214,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.168804,0.00273264,1.35178 kka2_1:4_G234N,kka2_1:4_234,Kka2,kka2_1:4,P00552,1.35191,NO,234,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-2.9,-3.105,0.205,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.168804,0.00984449,1.35191 kka2_1:4_L53I,kka2_1:4_53,Kka2,kka2_1:4,P00552,1.35229,NO,53,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-2.681,-2.859,0.178,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.168804,0.00671168,1.35229 kka2_1:2_E235Y,kka2_1:2_235,Kka2,kka2_1:2,P00552,1.35272,NO,235,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.955,-4.43,2.475,,0.631,H,A,1.04,0.12,26.048,26.048,65.53,OAH,-2.07267,0.295029,0.0102806,1.35272 kka2_1:2_Q42P,kka2_1:2_42,Kka2,kka2_1:2,P00552,1.35275,NO,42,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.907,-2.271,-0.636,,1.044,T,B,0.64,-0.8,2.792,,71.59,HPO,-2.12433,0.295029,0.00679212,1.35275 kka2_1:8_Q4M,kka2_1:8_4,Kka2,kka2_1:8,P00552,1.35289,NO,4,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.361,-4.464,2.103,,,,,,,2.026,,71.59,APA,-1.95533,0.100394,0.00239179,1.35289 kka2_1:8_Q4M,kka2_1:8_4,Kka2,kka2_1:8,P00552,1.35289,NO,4,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.361,-4.464,2.103,,,,,,,2.026,,71.59,APA,-1.95533,0.100394,0.00239179,1.35289 kka2_1:2_L47Y,kka2_1:2_47,Kka2,kka2_1:2,P00552,1.35291,NO,47,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.265,-3.972,2.707,,0.139,E,B,0.55,-0.86,2.369,,63.26,HHH,-1.77933,0.295029,0.00509386,1.35291 kka2_1:4_R239K,kka2_1:4_239,Kka2,kka2_1:4,P00552,1.35304,NO,239,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.949,-3.654,0.705,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.168804,0.00835326,1.35304 kka2_1:2_A56Q,kka2_1:2_56,Kka2,kka2_1:2,P00552,1.35314,NO,56,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.083,-4.08,1.997,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.295029,0.00717715,1.35314 beta-lactamase_0_H110T,beta-lactamase_0_110,TEM-1,beta-lactamase_0,P62593,1.35391,NO,110,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-1.706,-3.697,1.991,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.0500837,0.00441499,1.35391 kka2_1:4_D23N,kka2_1:4_23,Kka2,kka2_1:4,P00552,1.35432,NO,23,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-2.459,-3.82,1.361,,0.695,E,B,0.75,-0.65,2.416,,65.53,HAH,-1.94033,0.168804,0.007195,1.35432 kka2_1:4_A248V,kka2_1:4_248,Kka2,kka2_1:4,P00552,1.3544,NO,248,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.124,-2.592,0.468,,0.825,S,b,0.46,0.46,,,92.05,HHO,-2.15,0.168804,0.0125484,1.3544 kka2_1:4_T130K,kka2_1:4_130,Kka2,kka2_1:4,P00552,1.35466,NO,130,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.392,-3.096,0.704,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.168804,0.00804204,1.35466 kka2_1:4_S40K,kka2_1:4_40,Kka2,kka2_1:4,P00552,1.35477,NO,40,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.645,-2.814,0.169,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.168804,0.00693477,1.35477 kka2_1:2_L53S,kka2_1:2_53,Kka2,kka2_1:2,P00552,1.35481,NO,53,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-2.681,-2.891,0.21,,0.569,E,B,0.55,0.8,19.536,19.536,71.59,AHP,-2.47433,0.295029,0.00671168,1.35481 kka2_1:2_M178H,kka2_1:2_178,Kka2,kka2_1:2,P00552,1.35488,NO,178,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-3.206,-4.758,1.552,,0.554,.,b,0.55,0.68,3.152,,71.59,BHO,-2.154,0.295029,0.00717253,1.35488 kka2_1:2_A79H,kka2_1:2_79,Kka2,kka2_1:2,P00552,1.3549,NO,79,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.368,-3.321,0.953,,0.563,.,B,0.46,-0.43,0.475,,71.59,HHH,-1.752,0.295029,0.00664821,1.3549 kka2_1:2_E230H,kka2_1:2_230,Kka2,kka2_1:2,P00552,1.35511,NO,230,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.672,-2.411,-0.261,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.295029,0.00920051,1.35511 kka2_1:4_G234D,kka2_1:4_234,Kka2,kka2_1:4,P00552,1.35515,NO,234,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-2.9,-2.299,-0.601,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.168804,0.00984449,1.35515 kka2_1:8_A71N,kka2_1:8_71,Kka2,kka2_1:8,P00552,1.35515,NO,71,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.824,-2.731,0.907,,0.553,H,A,0.46,0.08,18.64,18.64,64.39,HHP,-1.74033,0.100394,0.00727707,1.35515 kka2_1:8_A71N,kka2_1:8_71,Kka2,kka2_1:8,P00552,1.35515,NO,71,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.824,-2.731,0.907,,0.553,H,A,0.46,0.08,18.64,18.64,64.39,HHP,-1.74033,0.100394,0.00727707,1.35515 kka2_1:4_S251Y,kka2_1:4_251,Kka2,kka2_1:4,P00552,1.35529,NO,251,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.636,-4.395,1.759,,0.712,H,A,0.77,-0.25,,,71.59,APP,-2.09367,0.168804,0.0138916,1.35529 kka2_1:2_A41Q,kka2_1:2_41,Kka2,kka2_1:2,P00552,1.35534,NO,41,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.879,-2.908,1.029,,0.184,.,B,0.46,-0.96,24.451,24.451,64.39,PHP,-2.477,0.295029,0.00543332,1.35534 kka2_1:4_F37Y,kka2_1:4_37,Kka2,kka2_1:4,P00552,1.35562,NO,37,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.427,-2.628,1.201,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.168804,0.00586193,1.35562 kka2_1:2_E111Q,kka2_1:2_111,Kka2,kka2_1:2,P00552,1.35583,NO,111,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.28,-2.347,0.067,,0.155,H,A,1.52,-1.14,2.792,,65.53,HAB,-2.27833,0.295029,0.00746789,1.35583 WW_domain_V171R,WW_domain_171,Yap65,WW_domain,P46937,1.35594,NO,171,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.547,-3.861,2.314,,,,,,,3.459,,70.24,AHO,-1.265,0.153962,0.00184125,1.35594 kka2_1:4_L53V,kka2_1:4_53,Kka2,kka2_1:4,P00552,1.35602,NO,53,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-2.681,-2.592,-0.089,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.168804,0.00671168,1.35602 kka2_1:4_G6Q,kka2_1:4_6,Kka2,kka2_1:4,P00552,1.35627,NO,6,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.685,-3.809,2.124,,,,,,,,,71.59,AOH,-1.639,0.168804,0.00204693,1.35627 kka2_1:4_G6L,kka2_1:4_6,Kka2,kka2_1:4,P00552,1.35642,NO,6,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.685,-3.363,1.678,,,,,,,,,71.59,AOH,-1.639,0.168804,0.00204693,1.35642 beta-lactamase_0_T138N,beta-lactamase_0_138,TEM-1,beta-lactamase_0,P62593,1.35666,NO,138,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-2.506,-2.961,0.455,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.0500837,0.00487868,1.35666 kka2_1:2_D180F,kka2_1:2_180,Kka2,kka2_1:2,P00552,1.35667,NO,180,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.416,-4.402,1.986,,1.03,S,a,0.75,1.5,1.27,,71.59,OAO,-2.02933,0.295029,0.00756412,1.35667 kka2_1:2_I141V,kka2_1:2_141,Kka2,kka2_1:2,P00552,1.35676,NO,141,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.495,-1.912,0.417,,0.068,H,A,0.48,-0.01,0.819,,92.05,BHA,-1.689,0.295029,0.00744745,1.35676 kka2_1:2_E149H,kka2_1:2_149,Kka2,kka2_1:2,P00552,1.35677,NO,149,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.994,-3.508,1.514,,0.674,H,A,1.04,1.63,15.361,15.361,71.59,HAH,-1.59667,0.295029,0.00803343,1.35677 kka2_1:4_S11A,kka2_1:4_11,Kka2,kka2_1:4,P00552,1.35711,NO,11,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.322,-2.34,0.018,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.168804,0.00381691,1.35711 kka2_1:4_R177V,kka2_1:4_177,Kka2,kka2_1:4,P00552,1.35749,NO,177,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.282,-3.636,1.354,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.168804,0.00768224,1.35749 kka2_1:2_D23S,kka2_1:2_23,Kka2,kka2_1:2,P00552,1.35758,NO,23,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.459,-2.448,-0.011,,0.695,E,B,0.75,-0.65,18.207,18.207,65.53,HAH,-1.94033,0.295029,0.007195,1.35758 kka2_1:2_L53K,kka2_1:2_53,Kka2,kka2_1:2,P00552,1.35797,NO,53,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-2.681,-3.091,0.41,,0.569,E,B,0.55,0.8,19.536,19.536,71.59,AHP,-2.47433,0.295029,0.00671168,1.35797 kka2_1:4_A14H,kka2_1:4_14,Kka2,kka2_1:4,P00552,1.35812,NO,14,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.837,-4.803,2.966,,0.728,G,A,0.46,0.7,0.36,,71.59,HHH,-1.82567,0.168804,0.00706614,1.35812 kka2_1:4_C77T,kka2_1:4_77,Kka2,kka2_1:4,P00552,1.35814,NO,77,C,T,CT,Special,Polar,5.07,5.6,0.53,149,121,119,-2,108.5,116.1,7.6,-1.477,-3.496,2.019,,0.229,B,b,0.46,-0.57,2.499,,63.26,OOH,-1.55667,0.168804,0.00441216,1.35814 kka2_1:4_F20Y,kka2_1:4_20,Kka2,kka2_1:4,P00552,1.35816,NO,20,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-3.354,-4.354,1,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.168804,0.00701744,1.35816 beta-lactamase_0_D99Q,beta-lactamase_0_99,TEM-1,beta-lactamase_0,P62593,1.35824,NO,99,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.191,-2.836,1.645,,0.402,G,A,0.75,0.36,0.374,,64.69,PAH,-1.794,0.0500837,0.00305446,1.35824 kka2_1:2_S251M,kka2_1:2_251,Kka2,kka2_1:2,P00552,1.35825,NO,251,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.636,-4.807,2.171,,0.712,H,A,0.27,-0.25,32.832,32.832,71.59,APP,-2.09367,0.295029,0.0138916,1.35825 kka2_1:4_P45K,kka2_1:4_45,Kka2,kka2_1:4,P00552,1.35851,NO,45,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.774,-2.635,0.861,,0.669,,B,0.52,-0.76,1.288,,71.59,BOH,-2.152,0.168804,0.00590481,1.35851 kka2_1:4_I2W,kka2_1:4_2,Kka2,kka2_1:4,P00552,1.35885,NO,2,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.787,-5.093,3.306,,,,,,,,,71.59,HHA,-1.92433,0.168804,0.00246644,1.35885 kka2_1:2_G234W,kka2_1:2_234,Kka2,kka2_1:2,P00552,1.3589,NO,234,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-2.9,-5.618,2.718,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.295029,0.00984449,1.3589 kka2_1:2_Q4K,kka2_1:2_4,Kka2,kka2_1:2,P00552,1.35901,NO,4,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.361,-3.145,0.784,,,,,,,2.026,,71.59,APA,-1.95533,0.295029,0.00239179,1.35901 kka2_1:4_A137R,kka2_1:4_137,Kka2,kka2_1:4,P00552,1.35916,NO,137,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.156,-3.088,0.932,,0.029,H,A,0.46,0.34,2.227,,63.26,PHB,-2.559,0.168804,0.00515054,1.35916 kka2_1:4_S251N,kka2_1:4_251,Kka2,kka2_1:4,P00552,1.35931,NO,251,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.636,-3.845,1.209,,0.712,H,A,0.77,-0.25,,,71.59,APP,-2.09367,0.168804,0.0138916,1.35931 beta-lactamase_0_S283K,beta-lactamase_0_283,TEM-1,beta-lactamase_0,P62593,1.35941,NO,283,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.638,,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.0500837,0.0429138,1.35941 kka2_1:4_D52T,kka2_1:4_52,Kka2,kka2_1:4,P00552,1.35942,NO,52,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.271,-3.473,1.202,,0.22,E,B,0.75,0.8,0.349,,71.59,PAH,-2.38367,0.168804,0.00175694,1.35942 kka2_1:4_L47H,kka2_1:4_47,Kka2,kka2_1:4,P00552,1.35972,NO,47,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.265,-4.833,3.568,,0.139,E,B,0.55,-0.86,2.369,,63.26,HHH,-1.77933,0.168804,0.00509386,1.35972 kka2_1:4_F20Q,kka2_1:4_20,Kka2,kka2_1:4,P00552,1.36022,NO,20,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-3.354,-3.237,-0.117,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.168804,0.00701744,1.36022 kka2_1:2_D23E,kka2_1:2_23,Kka2,kka2_1:2,P00552,1.36052,NO,23,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.459,-2.431,-0.028,,0.695,E,B,0.75,-0.65,18.207,18.207,65.53,HAH,-1.94033,0.295029,0.007195,1.36052 kka2_1:4_A255Y,kka2_1:4_255,Kka2,kka2_1:4,P00552,1.36064,NO,255,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.715,-3.332,1.617,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.168804,0.0126809,1.36064 kka2_1:2_H8Q,kka2_1:2_8,Kka2,kka2_1:2,P00552,1.36071,NO,8,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-2.759,-2.66,-0.099,,,,,,,,,71.59,HBH,-2.25467,0.295029,0.00256422,1.36071 kka2_1:4_T146A,kka2_1:4_146,Kka2,kka2_1:4,P00552,1.36117,NO,146,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-2.978,-1.627,-1.351,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.168804,0.00606474,1.36117 kka2_1:8_D238E,kka2_1:8_238,Kka2,kka2_1:8,P00552,1.36123,NO,238,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.83,-2.206,-0.624,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.100394,0.0113863,1.36123 kka2_1:8_D238E,kka2_1:8_238,Kka2,kka2_1:8,P00552,1.36123,NO,238,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.83,-2.206,-0.624,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.100394,0.0113863,1.36123 kka2_1:2_A35K,kka2_1:2_35,Kka2,kka2_1:2,P00552,1.36186,NO,35,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.127,-3.623,1.496,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.295029,0.00630016,1.36186 kka2_1:4_M178F,kka2_1:4_178,Kka2,kka2_1:4,P00552,1.36247,NO,178,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-3.206,-4.351,1.145,,0.554,.,b,0.55,0.68,9.913,9.913,71.59,BHO,-2.154,0.168804,0.00717253,1.36247 kka2_1:4_S40H,kka2_1:4_40,Kka2,kka2_1:4,P00552,1.36269,NO,40,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.645,-3.006,0.361,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.168804,0.00693477,1.36269 kka2_1:4_D238L,kka2_1:4_238,Kka2,kka2_1:4,P00552,1.36288,NO,238,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.83,-3.612,0.782,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.168804,0.0113863,1.36288 kka2_1:4_A13F,kka2_1:4_13,Kka2,kka2_1:4,P00552,1.36292,NO,13,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.248,-4.439,2.191,,0.689,G,A,0.46,0.99,,,92.05,OHH,-1.646,0.168804,0.00784241,1.36292 kka2_1:4_Q252W,kka2_1:4_252,Kka2,kka2_1:4,P00552,1.36292,NO,252,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.63,-5.559,2.929,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.168804,0.0121001,1.36292 beta-lactamase_0_I258D,beta-lactamase_0_258,TEM-1,beta-lactamase_0,P62593,1.36302,NO,258,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.0500837,0.007931,1.36302 kka2_1:4_D52I,kka2_1:4_52,Kka2,kka2_1:4,P00552,1.36314,NO,52,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.271,-4.062,1.791,,0.22,E,B,0.75,0.8,0.349,,71.59,PAH,-2.38367,0.168804,0.00175694,1.36314 kka2_1:4_L7S,kka2_1:4_7,Kka2,kka2_1:4,P00552,1.36324,NO,7,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.926,-3.278,1.352,,,,,,,3.012,,71.59,OHB,-2.12333,0.168804,0.00269456,1.36324 kka2_1:2_D52T,kka2_1:2_52,Kka2,kka2_1:2,P00552,1.36325,NO,52,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.271,-3.473,1.202,,0.22,E,B,0.75,0.8,1.123,,71.59,PAH,-2.38367,0.295029,0.00175694,1.36325 kka2_1:4_A87H,kka2_1:4_87,Kka2,kka2_1:4,P00552,1.3635,NO,87,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.917,-3.188,1.271,,1.039,S,L,0.46,1.57,22.675,22.675,65.53,AHO,-1.822,0.168804,0.00791281,1.3635 beta-lactamase_0_R273F,beta-lactamase_0_273,TEM-1,beta-lactamase_0,P62593,1.36374,NO,273,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.314,-4.428,2.114,,0.564,H,A,1.2,1.57,20.248,20.248,73.78,ABP,-1.841,0.0500837,0.0077952,1.36374 kka2_1:8_A25H,kka2_1:8_25,Kka2,kka2_1:8,P00552,1.36375,NO,25,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.496,-3.145,0.649,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.100394,0.00595636,1.36375 kka2_1:8_A25H,kka2_1:8_25,Kka2,kka2_1:8,P00552,1.36375,NO,25,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.496,-3.145,0.649,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.100394,0.00595636,1.36375 kka2_1:4_I254M,kka2_1:4_254,Kka2,kka2_1:4,P00552,1.36386,NO,254,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.933,-2.224,0.291,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.168804,0.0132375,1.36386 beta-lactamase_0_V214A,beta-lactamase_0_214,TEM-1,beta-lactamase_0,P62593,1.36387,NO,214,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-1.299,-2.434,1.135,,0.375,S,A,0.44,-0.44,3.712,,74.48,BHH,-1.53733,0.0500837,0.00628442,1.36387 kka2_1:2_A255G,kka2_1:2_255,Kka2,kka2_1:2,P00552,1.36412,NO,255,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.715,-2.509,0.794,,0.466,H,A,0.46,-0.52,5.144,,65.53,HHH,-1.71267,0.295029,0.0126809,1.36412 kka2_1:8_G10P,kka2_1:8_10,Kka2,kka2_1:8,P00552,1.36417,NO,10,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.921,-2.317,0.396,,,,,,,1.862,,71.59,HOP,-2.10733,0.100394,0.00289233,1.36417 kka2_1:8_G10P,kka2_1:8_10,Kka2,kka2_1:8,P00552,1.36417,NO,10,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.921,-2.317,0.396,,,,,,,1.862,,71.59,HOP,-2.10733,0.100394,0.00289233,1.36417 beta-lactamase_0_R239Q,beta-lactamase_0_239,TEM-1,beta-lactamase_0,P62593,1.36427,NO,239,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-0.819,,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.0500837,0.00213852,1.36427 kka2_1:2_A248M,kka2_1:2_248,Kka2,kka2_1:2,P00552,1.36434,NO,248,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.124,-4.765,2.641,,0.825,S,b,0.46,0.46,,,92.05,HHO,-2.15,0.295029,0.0125484,1.36434 beta-lactamase_0_K232N,beta-lactamase_0_232,TEM-1,beta-lactamase_0,P62593,1.36443,NO,232,K,N,KN,PositiveCharge,Polar,9.74,5.47157,-4.26843,94,146,132,-14,168.6,114.1,-54.5,-1.012,-3.49,2.478,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.0500837,0.00313441,1.36443 kka2_1:4_T225H,kka2_1:4_225,Kka2,kka2_1:4,P00552,1.36461,NO,225,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.393,-3.458,1.065,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.168804,0.0113598,1.36461 kka2_1:2_S251T,kka2_1:2_251,Kka2,kka2_1:2,P00552,1.36464,NO,251,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.636,-3.052,0.416,,0.712,H,A,0.27,-0.25,32.832,32.832,71.59,APP,-2.09367,0.295029,0.0138916,1.36464 kka2_1:2_D5V,kka2_1:2_5,Kka2,kka2_1:2,P00552,1.36481,NO,5,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.306,-3.484,2.178,,,,,,,,,71.59,PAO,-1.784,0.295029,0.00222864,1.36481 kka2_1:4_D23Q,kka2_1:4_23,Kka2,kka2_1:4,P00552,1.3649,NO,23,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.459,-3.078,0.619,,0.695,E,B,0.75,-0.65,2.416,,65.53,HAH,-1.94033,0.168804,0.007195,1.3649 kka2_1:8_A248M,kka2_1:8_248,Kka2,kka2_1:8,P00552,1.36536,NO,248,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.124,-4.765,2.641,,0.825,S,b,1.04,0.46,11.329,11.329,92.05,HHO,-2.15,0.100394,0.0125484,1.36536 kka2_1:8_A248M,kka2_1:8_248,Kka2,kka2_1:8,P00552,1.36536,NO,248,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.124,-4.765,2.641,,0.825,S,b,1.04,0.46,11.329,11.329,92.05,HHO,-2.15,0.100394,0.0125484,1.36536 kka2_1:2_E199C,kka2_1:2_199,Kka2,kka2_1:2,P00552,1.36542,NO,199,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.234,-3.64,1.406,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.295029,0.00854122,1.36542 kka2_1:2_F20E,kka2_1:2_20,Kka2,kka2_1:2,P00552,1.36543,NO,20,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-3.354,-2.8,-0.554,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.295029,0.00701744,1.36543 kka2_1:4_E3C,kka2_1:4_3,Kka2,kka2_1:4,P00552,1.36543,NO,3,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.199,-4.909,2.71,,,,,,,7.22,,92.05,HAP,-2.11567,0.168804,0.00267607,1.36543 kka2_1:4_A255H,kka2_1:4_255,Kka2,kka2_1:4,P00552,1.36567,NO,255,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.715,-3.488,1.773,,0.466,H,A,1.04,-0.52,5.144,,65.53,HHH,-1.71267,0.168804,0.0126809,1.36567 kka2_1:8_L232F,kka2_1:8_232,Kka2,kka2_1:8,P00552,1.36572,NO,232,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.514,-2.061,0.547,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.100394,0.00800103,1.36572 kka2_1:8_L232F,kka2_1:8_232,Kka2,kka2_1:8,P00552,1.36572,NO,232,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.514,-2.061,0.547,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.100394,0.00800103,1.36572 beta-lactamase_0_Q203M,beta-lactamase_0_203,TEM-1,beta-lactamase_0,P62593,1.36588,NO,203,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.168,-4.659,2.491,,0.47,H,A,0.64,-0.38,14.541,14.541,65.38,BPP,-1.614,0.0500837,0.00631514,1.36588 kka2_1:2_H106Q,kka2_1:2_106,Kka2,kka2_1:2,P00552,1.36588,NO,106,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-3.13,-3.142,0.012,,1.065,.,a,0.17,-0.95,2.53,,71.59,PBH,-2.10433,0.295029,0.00730778,1.36588 beta-lactamase_0_V214S,beta-lactamase_0_214,TEM-1,beta-lactamase_0,P62593,1.366,NO,214,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.299,-3.408,2.109,,0.375,S,A,0.44,-0.44,3.712,,74.48,BHH,-1.53733,0.0500837,0.00628442,1.366 kka2_1:2_A13R,kka2_1:2_13,Kka2,kka2_1:2,P00552,1.36642,NO,13,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.248,-2.994,0.746,,0.689,G,A,0.46,0.99,,,92.05,OHH,-1.646,0.295029,0.00784241,1.36642 kka2_1:4_Q163C,kka2_1:4_163,Kka2,kka2_1:4,P00552,1.36651,NO,163,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.162,-5.049,2.887,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.168804,0.00719507,1.36651 kka2_1:4_S251H,kka2_1:4_251,Kka2,kka2_1:4,P00552,1.3671,NO,251,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.636,-3.222,0.586,,0.712,H,A,0.77,-0.25,,,71.59,APP,-2.09367,0.168804,0.0138916,1.3671 kka2_1:2_L165I,kka2_1:2_165,Kka2,kka2_1:2,P00552,1.36726,NO,165,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-2.453,-3.855,1.402,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.295029,0.00801161,1.36726 kka2_1:2_R177V,kka2_1:2_177,Kka2,kka2_1:2,P00552,1.36727,NO,177,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.282,-3.636,1.354,,0.521,T,A,1.2,0.16,1.842,,63.64,HBH,-2.36967,0.295029,0.00768224,1.36727 kka2_1:2_H8V,kka2_1:2_8,Kka2,kka2_1:2,P00552,1.36737,NO,8,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-2.759,-3.205,0.446,,,,,,,,,71.59,HBH,-2.25467,0.295029,0.00256422,1.36737 kka2_1:2_L126I,kka2_1:2_126,Kka2,kka2_1:2,P00552,1.3674,NO,126,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.246,-2.028,0.782,,0.285,S,B,0.55,0.12,1.392,,51.89,PHA,-1.744,0.295029,0.0066485,1.3674 kka2_1:2_Q163E,kka2_1:2_163,Kka2,kka2_1:2,P00552,1.36762,NO,163,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.162,-2.572,0.41,,0.58,T,B,0.64,1.85,3.888,,64.02,BPO,-1.78333,0.295029,0.00719507,1.36762 kka2_1:8_A248K,kka2_1:8_248,Kka2,kka2_1:8,P00552,1.36778,NO,248,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.124,-2.875,0.751,,0.825,S,b,1.04,0.46,11.329,11.329,92.05,HHO,-2.15,0.100394,0.0125484,1.36778 kka2_1:8_A248K,kka2_1:8_248,Kka2,kka2_1:8,P00552,1.36778,NO,248,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.124,-2.875,0.751,,0.825,S,b,1.04,0.46,11.329,11.329,92.05,HHO,-2.15,0.100394,0.0125484,1.36778 kka2_1:4_G234Y,kka2_1:4_234,Kka2,kka2_1:4,P00552,1.368,NO,234,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-2.9,-4.454,1.554,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.168804,0.00984449,1.368 kka2_1:4_H106Q,kka2_1:4_106,Kka2,kka2_1:4,P00552,1.36814,NO,106,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-3.13,-3.142,0.012,,1.065,.,a,0.17,-0.95,16.74,16.74,71.59,PBH,-2.10433,0.168804,0.00730778,1.36814 kka2_1:2_S251I,kka2_1:2_251,Kka2,kka2_1:2,P00552,1.36869,NO,251,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.636,-4.095,1.459,,0.712,H,A,0.27,-0.25,32.832,32.832,71.59,APP,-2.09367,0.295029,0.0138916,1.36869 kka2_1:4_V46I,kka2_1:4_46,Kka2,kka2_1:4,P00552,1.36898,NO,46,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-2.62,-3.923,1.303,,0.192,.,B,0.44,-1.12,9.564,,92.05,OHH,-1.88633,0.168804,0.00631301,1.36898 kka2_1:4_S251D,kka2_1:4_251,Kka2,kka2_1:4,P00552,1.36902,NO,251,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.636,-2.837,0.201,,0.712,H,A,0.77,-0.25,,,71.59,APP,-2.09367,0.168804,0.0138916,1.36902 kka2_1:4_L47Y,kka2_1:4_47,Kka2,kka2_1:4,P00552,1.36905,NO,47,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.265,-3.972,2.707,,0.139,E,B,0.55,-0.86,2.369,,63.26,HHH,-1.77933,0.168804,0.00509386,1.36905 beta-lactamase_0_R220D,beta-lactamase_0_220,TEM-1,beta-lactamase_0,P62593,1.3691,NO,220,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-0.942,-3.72,2.778,,0.295,I,A,1.2,-0.76,21.573,21.573,74.48,HBP,-1.33633,0.0500837,0.00232421,1.3691 kka2_1:4_E3H,kka2_1:4_3,Kka2,kka2_1:4,P00552,1.3695,NO,3,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.199,-4.214,2.015,,,,,,,7.22,,92.05,HAP,-2.11567,0.168804,0.00267607,1.3695 kka2_1:2_Q155L,kka2_1:2_155,Kka2,kka2_1:2,P00552,1.37006,NO,155,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.606,-3.573,0.967,,0.525,T,A,0.64,1.49,1.592,,63.64,APA,-1.726,0.295029,0.00641853,1.37006 kka2_1:4_A176D,kka2_1:4_176,Kka2,kka2_1:4,P00552,1.37054,NO,176,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.621,-2.955,1.334,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.168804,0.0083587,1.37054 beta-lactamase_0_R118Y,beta-lactamase_0_118,TEM-1,beta-lactamase_0,P62593,1.37056,NO,118,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.413,-4.398,1.985,,0.457,H,A,1.2,1.39,3.961,,77.62,HBA,-1.785,0.0500837,0.00538794,1.37056 kka2_1:4_E111L,kka2_1:4_111,Kka2,kka2_1:4,P00552,1.37066,NO,111,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.28,-3.101,0.821,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.168804,0.00746789,1.37066 kka2_1:2_Q42K,kka2_1:2_42,Kka2,kka2_1:2,P00552,1.3707,NO,42,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-2.907,-2.899,-0.008,,1.044,T,B,0.64,-0.8,2.792,,71.59,HPO,-2.12433,0.295029,0.00679212,1.3707 beta-lactamase_0_K232S,beta-lactamase_0_232,TEM-1,beta-lactamase_0,P62593,1.37076,NO,232,K,S,KS,PositiveCharge,Polar,9.74,5.68,-4.06,121,146,105,-41,168.6,89,-79.6,-1.012,-3.258,2.246,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.0500837,0.00313441,1.37076 kka2_1:2_H8K,kka2_1:2_8,Kka2,kka2_1:2,P00552,1.37076,NO,8,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-2.759,-3.463,0.704,,,,,,,,,71.59,HBH,-2.25467,0.295029,0.00256422,1.37076 kka2_1:2_M178W,kka2_1:2_178,Kka2,kka2_1:2,P00552,1.37076,NO,178,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-3.206,-5.507,2.301,,0.554,.,b,0.55,0.68,3.152,,71.59,BHO,-2.154,0.295029,0.00717253,1.37076 kka2_1:4_D238V,kka2_1:4_238,Kka2,kka2_1:4,P00552,1.37079,NO,238,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.83,-3.676,0.846,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.168804,0.0113863,1.37079 kka2_1:2_R143H,kka2_1:2_143,Kka2,kka2_1:2,P00552,1.37095,NO,143,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.525,-3.575,1.05,,0.325,H,A,0.16,1.22,14.853,14.853,65.53,ABH,-1.86833,0.295029,0.00662247,1.37095 kka2_1:4_V75I,kka2_1:4_75,Kka2,kka2_1:4,P00552,1.37106,NO,75,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-2.06,-1.939,-0.121,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.168804,0.00693733,1.37106 kka2_1:4_P249K,kka2_1:4_249,Kka2,kka2_1:4,P00552,1.37121,NO,249,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.867,-3.802,1.935,,0.406,.,B,0.52,-0.01,,,92.05,HOA,-1.66867,0.168804,0.011045,1.37121 kka2_1:2_Q4E,kka2_1:2_4,Kka2,kka2_1:2,P00552,1.37143,NO,4,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.361,-3.058,0.697,,,,,,,2.026,,71.59,APA,-1.95533,0.295029,0.00239179,1.37143 kka2_1:4_A247K,kka2_1:4_247,Kka2,kka2_1:4,P00552,1.37228,NO,247,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.459,-3.008,0.549,,1.01,S,A,0.46,0.65,,,92.05,HHH,-2.197,0.168804,0.0102428,1.37228 kka2_1:4_E3D,kka2_1:4_3,Kka2,kka2_1:4,P00552,1.37232,NO,3,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.199,-1.902,-0.297,,,,,,,7.22,,92.05,HAP,-2.11567,0.168804,0.00267607,1.37232 kka2_1:4_E230H,kka2_1:4_230,Kka2,kka2_1:4,P00552,1.37235,NO,230,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.672,-2.411,-0.261,,0.807,H,A,1.52,0.11,6.966,,63.26,HAA,-2.13767,0.168804,0.00920051,1.37235 kka2_1:4_R177A,kka2_1:4_177,Kka2,kka2_1:4,P00552,1.37241,NO,177,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.282,-2.56,0.278,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.168804,0.00768224,1.37241 kka2_1:2_E3D,kka2_1:2_3,Kka2,kka2_1:2,P00552,1.37244,NO,3,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.199,-1.902,-0.297,,,,,,,7.22,,92.05,HAP,-2.11567,0.295029,0.00267607,1.37244 kka2_1:4_D238C,kka2_1:4_238,Kka2,kka2_1:4,P00552,1.37322,NO,238,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.83,-5.149,2.319,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.168804,0.0113863,1.37322 kka2_1:4_G43R,kka2_1:4_43,Kka2,kka2_1:4,P00552,1.37366,NO,43,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.587,-2.733,1.146,,0.862,T,l,0.75,-0.67,2.247,,63.26,POB,-2.18533,0.168804,0.0071925,1.37366 kka2_1:4_E199A,kka2_1:4_199,Kka2,kka2_1:4,P00552,1.3738,NO,199,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.234,-2.101,-0.133,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.168804,0.00854122,1.3738 kka2_1:4_R173Q,kka2_1:4_173,Kka2,kka2_1:4,P00552,1.37382,NO,173,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.407,-2.729,0.322,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.168804,0.00784999,1.37382 kka2_1:8_E86Q,kka2_1:8_86,Kka2,kka2_1:8,P00552,1.37388,NO,86,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.86,-2.883,1.023,,0.369,,B,1.52,1.92,,,63.26,PAH,-1.98067,0.100394,0.00642858,1.37388 kka2_1:8_E86Q,kka2_1:8_86,Kka2,kka2_1:8,P00552,1.37388,NO,86,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.86,-2.883,1.023,,0.369,,B,1.52,1.92,,,63.26,PAH,-1.98067,0.100394,0.00642858,1.37388 kka2_1:8_Y244M,kka2_1:8_244,Kka2,kka2_1:8,P00552,1.3739,NO,244,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-0.775,-4.508,3.733,,0.066,H,A,1.25,-0.64,,,,HHO,-1.41267,0.100394,0.00453187,1.3739 kka2_1:8_Y244M,kka2_1:8_244,Kka2,kka2_1:8,P00552,1.3739,NO,244,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-0.775,-4.508,3.733,,0.066,H,A,1.25,-0.64,,,,HHO,-1.41267,0.100394,0.00453187,1.3739 kka2_1:4_D250C,kka2_1:4_250,Kka2,kka2_1:4,P00552,1.37453,NO,250,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.015,-5.204,4.189,,0.274,.,b,0.75,-0.46,0.307,,51.89,OAP,-1.83933,0.168804,0.0177103,1.37453 kka2_1:4_D180I,kka2_1:4_180,Kka2,kka2_1:4,P00552,1.37459,NO,180,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.416,-3.372,0.956,,1.03,S,a,0.29,1.5,14.668,14.668,71.59,OAO,-2.02933,0.168804,0.00756412,1.37459 kka2_1:4_E96Q,kka2_1:4_96,Kka2,kka2_1:4,P00552,1.37459,NO,96,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-2.573,-3.937,1.364,,0.476,,B,1.52,-0.65,1.254,,71.59,OAH,-2.143,0.168804,0.00369441,1.37459 kka2_1:2_D5G,kka2_1:2_5,Kka2,kka2_1:2,P00552,1.37489,NO,5,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-1.306,-3.014,1.708,,,,,,,,,71.59,PAO,-1.784,0.295029,0.00222864,1.37489 kka2_1:4_Q61S,kka2_1:4_61,Kka2,kka2_1:4,P00552,1.37499,NO,61,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.982,-2.728,-0.254,,0.591,H,A,0.64,0.41,3.484,,65.53,HPA,-1.85667,0.168804,0.00612092,1.37499 kka2_1:4_G95K,kka2_1:4_95,Kka2,kka2_1:4,P00552,1.37504,NO,95,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-2.403,-3.514,1.111,,0.126,E,B,0.29,-0.74,0.359,,71.59,HOA,-2.198,0.168804,0.00743616,1.37504 beta-lactamase_0_A182K,beta-lactamase_0_182,TEM-1,beta-lactamase_0,P62593,1.37506,NO,182,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.777,-2.859,1.082,,0.136,H,A,0.46,-0.66,10.765,10.765,93.01,OHH,-1.27367,0.0500837,0.00559099,1.37506 kka2_1:2_A13G,kka2_1:2_13,Kka2,kka2_1:2,P00552,1.37519,NO,13,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.248,-2.748,0.5,,0.689,G,A,0.46,0.99,,,92.05,OHH,-1.646,0.295029,0.00784241,1.37519 kka2_1:2_V83K,kka2_1:2_83,Kka2,kka2_1:2,P00552,1.37525,NO,83,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-2.567,-3.653,1.086,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.295029,0.00650486,1.37525 kka2_1:4_F20H,kka2_1:4_20,Kka2,kka2_1:4,P00552,1.37556,NO,20,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-3.354,-4.805,1.451,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.168804,0.00701744,1.37556 kka2_1:4_G151N,kka2_1:4_151,Kka2,kka2_1:4,P00552,1.37572,NO,151,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.873,-2.707,1.834,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.168804,0.00339918,1.37572 kka2_1:4_A247T,kka2_1:4_247,Kka2,kka2_1:4,P00552,1.37595,NO,247,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.459,-2.783,0.324,,1.01,S,A,0.46,0.65,,,92.05,HHH,-2.197,0.168804,0.0102428,1.37595 kka2_1:8_A247R,kka2_1:8_247,Kka2,kka2_1:8,P00552,1.37595,NO,247,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.459,-3.186,0.727,,1.01,S,A,0.46,0.65,18.904,18.904,92.05,HHH,-2.197,0.100394,0.0102428,1.37595 kka2_1:8_A247R,kka2_1:8_247,Kka2,kka2_1:8,P00552,1.37595,NO,247,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.459,-3.186,0.727,,1.01,S,A,0.46,0.65,18.904,18.904,92.05,HHH,-2.197,0.100394,0.0102428,1.37595 kka2_1:4_T73Q,kka2_1:4_73,Kka2,kka2_1:4,P00552,1.37611,NO,73,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.51,-1.983,-0.527,,0.309,H,A,0.22,0.35,1.53,,56.06,PPO,-2.02333,0.168804,0.00628605,1.37611 kka2_1:4_S251T,kka2_1:4_251,Kka2,kka2_1:4,P00552,1.37659,NO,251,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.636,-3.052,0.416,,0.712,H,A,0.77,-0.25,,,71.59,APP,-2.09367,0.168804,0.0138916,1.37659 kka2_1:4_R177Y,kka2_1:4_177,Kka2,kka2_1:4,P00552,1.3766,NO,177,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.282,-4.382,2.1,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.168804,0.00768224,1.3766 kka2_1:4_S11M,kka2_1:4_11,Kka2,kka2_1:4,P00552,1.37664,NO,11,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.322,-2.896,0.574,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.168804,0.00381691,1.37664 kka2_1:4_L47K,kka2_1:4_47,Kka2,kka2_1:4,P00552,1.37665,NO,47,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.265,-3.649,2.384,,0.139,E,B,0.55,-0.86,2.369,,63.26,HHH,-1.77933,0.168804,0.00509386,1.37665 kka2_1:4_G234H,kka2_1:4_234,Kka2,kka2_1:4,P00552,1.37671,NO,234,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-2.9,-4.698,1.798,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.168804,0.00984449,1.37671 kka2_1:4_A176H,kka2_1:4_176,Kka2,kka2_1:4,P00552,1.37676,NO,176,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.621,-4.691,3.07,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.168804,0.0083587,1.37676 kka2_1:4_R177W,kka2_1:4_177,Kka2,kka2_1:4,P00552,1.37677,NO,177,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.282,-5.514,3.232,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.168804,0.00768224,1.37677 kka2_1:4_R173M,kka2_1:4_173,Kka2,kka2_1:4,P00552,1.3768,NO,173,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.407,-4.764,2.357,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.168804,0.00784999,1.3768 kka2_1:2_F20D,kka2_1:2_20,Kka2,kka2_1:2,P00552,1.37697,NO,20,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-3.354,-3.734,0.38,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.295029,0.00701744,1.37697 beta-lactamase_0_K232Q,beta-lactamase_0_232,TEM-1,beta-lactamase_0,P62593,1.37699,NO,232,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-1.012,-3.492,2.48,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.0500837,0.00313441,1.37699 beta-lactamase_0_E119R,beta-lactamase_0_119,TEM-1,beta-lactamase_0,P62593,1.37717,NO,119,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.412,-3.743,2.331,,0.358,H,A,1.04,0.51,3.396,,63.99,BAH,-1.623,0.0500837,0.00386966,1.37717 kka2_1:2_E3R,kka2_1:2_3,Kka2,kka2_1:2,P00552,1.37728,NO,3,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.199,-3.722,1.523,,,,,,,7.22,,92.05,HAP,-2.11567,0.295029,0.00267607,1.37728 kka2_1:2_T146R,kka2_1:2_146,Kka2,kka2_1:2,P00552,1.37738,NO,146,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.978,-2.581,-0.397,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.295029,0.00606474,1.37738 kka2_1:2_T73Q,kka2_1:2_73,Kka2,kka2_1:2,P00552,1.3776,NO,73,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.51,-1.983,-0.527,,0.309,H,A,0.22,0.35,4.114,,56.06,PPO,-2.02333,0.295029,0.00628605,1.3776 kka2_1:4_L165V,kka2_1:4_165,Kka2,kka2_1:4,P00552,1.37763,NO,165,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-2.453,-2.841,0.388,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.168804,0.00801161,1.37763 beta-lactamase_0_A124Y,beta-lactamase_0_124,TEM-1,beta-lactamase_0,P62593,1.37809,NO,124,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.181,-4.228,3.047,,,H,A,0.46,-0.9,1.876,,64.34,HHH,-1.152,0.0500837,0.00481399,1.37809 kka2_1:2_M178C,kka2_1:2_178,Kka2,kka2_1:2,P00552,1.37838,NO,178,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-3.206,-3.246,0.04,,0.554,.,b,0.55,0.68,3.152,,71.59,BHO,-2.154,0.295029,0.00717253,1.37838 kka2_1:2_G234M,kka2_1:2_234,Kka2,kka2_1:2,P00552,1.37841,NO,234,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-2.9,-4.839,1.939,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.295029,0.00984449,1.37841 kka2_1:4_R18N,kka2_1:4_18,Kka2,kka2_1:4,P00552,1.37845,NO,18,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.055,-3.899,1.844,,0.474,T,A,1.2,0.54,8.405,8.405,71.59,ABH,-1.821,0.168804,0.00724065,1.37845 kka2_1:2_L7S,kka2_1:2_7,Kka2,kka2_1:2,P00552,1.37922,NO,7,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.926,-3.278,1.352,,,,,,,3.012,,71.59,OHB,-2.12333,0.295029,0.00269456,1.37922 kka2_1:4_A79N,kka2_1:4_79,Kka2,kka2_1:4,P00552,1.37938,NO,79,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.368,-3.84,1.472,,0.563,.,B,0.46,-0.43,2.291,,71.59,HHH,-1.752,0.168804,0.00664821,1.37938 kka2_1:2_A247T,kka2_1:2_247,Kka2,kka2_1:2,P00552,1.37943,NO,247,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.459,-2.783,0.324,,1.01,S,A,0.46,0.65,0.828,,92.05,HHH,-2.197,0.295029,0.0102428,1.37943 beta-lactamase_0_V157G,beta-lactamase_0_157,TEM-1,beta-lactamase_0,P62593,1.37961,NO,157,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.751,-3.625,1.874,,0.308,S,a,0.44,-0.75,3.106,,69.58,BHP,-2.00767,0.0500837,0.00506849,1.37961 kka2_1:4_Q4N,kka2_1:4_4,Kka2,kka2_1:4,P00552,1.37996,NO,4,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.361,-1.87,-0.491,,,,,,,2.026,,71.59,APA,-1.95533,0.168804,0.00239179,1.37996 kka2_1:2_A247R,kka2_1:2_247,Kka2,kka2_1:2,P00552,1.38011,NO,247,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.459,-3.186,0.727,,1.01,S,A,0.46,0.65,0.828,,92.05,HHH,-2.197,0.295029,0.0102428,1.38011 kka2_1:4_A79R,kka2_1:4_79,Kka2,kka2_1:4,P00552,1.38015,NO,79,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.368,-2.341,-0.027,,0.563,.,B,0.46,-0.43,2.291,,71.59,HHH,-1.752,0.168804,0.00664821,1.38015 kka2_1:2_E199H,kka2_1:2_199,Kka2,kka2_1:2,P00552,1.38023,NO,199,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.234,-3.025,0.791,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.295029,0.00854122,1.38023 kka2_1:4_T146R,kka2_1:4_146,Kka2,kka2_1:4,P00552,1.38028,NO,146,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.978,-2.581,-0.397,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.168804,0.00606474,1.38028 kka2_1:4_S40Q,kka2_1:4_40,Kka2,kka2_1:4,P00552,1.38044,NO,40,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.645,-2.827,0.182,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.168804,0.00693477,1.38044 kka2_1:2_A168R,kka2_1:2_168,Kka2,kka2_1:2,P00552,1.38045,NO,168,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.989,-3.003,1.014,,0.67,H,A,0.46,0.15,25.546,25.546,64.39,OHA,-2.12933,0.295029,0.00806773,1.38045 beta-lactamase_0_I93N,beta-lactamase_0_93,TEM-1,beta-lactamase_0,P62593,1.38079,NO,93,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.401,-4.175,2.774,,0.128,E,B,0.48,0.44,1.266,,67.83,BHB,-1.873,0.0500837,0.00527066,1.38079 kka2_1:4_G6E,kka2_1:4_6,Kka2,kka2_1:4,P00552,1.38103,NO,6,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.685,-3.379,1.694,,,,,,,,,71.59,AOH,-1.639,0.168804,0.00204693,1.38103 kka2_1:4_L7V,kka2_1:4_7,Kka2,kka2_1:4,P00552,1.38108,NO,7,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.926,-3.173,1.247,,,,,,,3.012,,71.59,OHB,-2.12333,0.168804,0.00269456,1.38108 kka2_1:2_A176D,kka2_1:2_176,Kka2,kka2_1:2,P00552,1.38123,NO,176,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.621,-2.955,1.334,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.295029,0.0083587,1.38123 kka2_1:4_E3K,kka2_1:4_3,Kka2,kka2_1:4,P00552,1.3814,NO,3,E,K,EK,negativeCharge,PositiveCharge,3.22,9.74,6.52,56,147,146,-1,138.4,168.6,30.2,-2.199,-3.312,1.113,,,,,,,7.22,,92.05,HAP,-2.11567,0.168804,0.00267607,1.3814 kka2_1:2_D5A,kka2_1:2_5,Kka2,kka2_1:2,P00552,1.38199,NO,5,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-1.306,-3.033,1.727,,,,,,,,,71.59,PAO,-1.784,0.295029,0.00222864,1.38199 kka2_1:2_V46G,kka2_1:2_46,Kka2,kka2_1:2,P00552,1.38209,NO,46,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-2.62,-2.793,0.173,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.295029,0.00631301,1.38209 kka2_1:2_D5S,kka2_1:2_5,Kka2,kka2_1:2,P00552,1.38216,NO,5,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.306,-2.972,1.666,,,,,,,,,71.59,PAO,-1.784,0.295029,0.00222864,1.38216 kka2_1:4_E3I,kka2_1:4_3,Kka2,kka2_1:4,P00552,1.38231,NO,3,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.199,-3.832,1.633,,,,,,,7.22,,92.05,HAP,-2.11567,0.168804,0.00267607,1.38231 kka2_1:4_D33G,kka2_1:4_33,Kka2,kka2_1:4,P00552,1.38239,NO,33,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.186,-2.077,-0.109,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.168804,0.00633568,1.38239 beta-lactamase_0_E272L,beta-lactamase_0_272,TEM-1,beta-lactamase_0,P62593,1.38264,NO,272,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.0500837,0.00545371,1.38264 beta-lactamase_0_A148W,beta-lactamase_0_148,TEM-1,beta-lactamase_0,P62593,1.38282,NO,148,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.757,-5.497,3.74,,0.379,H,A,0.46,-0.55,19.42,19.42,72.73,PHH,-1.40167,0.0500837,0.00547053,1.38282 kka2_1:2_H8R,kka2_1:2_8,Kka2,kka2_1:2,P00552,1.38353,NO,8,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-2.759,-3.714,0.955,,,,,,,,,71.59,HBH,-2.25467,0.295029,0.00256422,1.38353 kka2_1:2_G234L,kka2_1:2_234,Kka2,kka2_1:2,P00552,1.38387,NO,234,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-2.9,-3.687,0.787,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.295029,0.00984449,1.38387 kka2_1:2_S251N,kka2_1:2_251,Kka2,kka2_1:2,P00552,1.38419,NO,251,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.636,-3.845,1.209,,0.712,H,A,0.27,-0.25,32.832,32.832,71.59,APP,-2.09367,0.295029,0.0138916,1.38419 kka2_1:4_A71Q,kka2_1:4_71,Kka2,kka2_1:4,P00552,1.38452,NO,71,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.824,-2.665,0.841,,0.553,H,A,0.46,0.08,5.76,,64.39,HHP,-1.74033,0.168804,0.00727707,1.38452 kka2_1:2_E149I,kka2_1:2_149,Kka2,kka2_1:2,P00552,1.38454,NO,149,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.994,-3.262,1.268,,0.674,H,A,1.04,1.63,15.361,15.361,71.59,HAH,-1.59667,0.295029,0.00803343,1.38454 beta-lactamase_0_V78N,beta-lactamase_0_78,TEM-1,beta-lactamase_0,P62593,1.38548,NO,78,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.459,-4.189,2.73,,,H,A,0.44,-0.47,16.615,16.615,63.64,HHH,-1.17833,0.0500837,0.00492501,1.38548 beta-lactamase_0_A278Q,beta-lactamase_0_278,TEM-1,beta-lactamase_0,P62593,1.38559,NO,278,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.348,,,,0.015,H,A,0.48,-0.85,4.624,,63.29,HHA,-1.41833,0.0500837,0.0310297,1.38559 beta-lactamase_0_D129H,beta-lactamase_0_129,TEM-1,beta-lactamase_0,P62593,1.38601,NO,129,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-0.816,-4.453,3.637,,,,B,0.75,-0.69,2.66,,34.97,PAP,-0.818,0.0500837,0.00109178,1.38601 kka2_1:4_A41Q,kka2_1:4_41,Kka2,kka2_1:4,P00552,1.38607,NO,41,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.879,-2.908,1.029,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.168804,0.00543332,1.38607 kka2_1:8_R239Q,kka2_1:8_239,Kka2,kka2_1:8,P00552,1.3874,NO,239,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.949,-4.068,1.119,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.100394,0.00835326,1.3874 kka2_1:8_R239Q,kka2_1:8_239,Kka2,kka2_1:8,P00552,1.3874,NO,239,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.949,-4.068,1.119,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.100394,0.00835326,1.3874 kka2_1:2_Q155S,kka2_1:2_155,Kka2,kka2_1:2,P00552,1.38752,NO,155,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.606,-3.295,0.689,,0.525,T,A,0.64,1.49,1.592,,63.64,APA,-1.726,0.295029,0.00641853,1.38752 kka2_1:2_P167L,kka2_1:2_167,Kka2,kka2_1:2,P00552,1.38765,NO,167,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-2.403,-2.565,0.162,,0.18,H,A,0.52,0.75,3.6,,64.39,HOH,-2.26633,0.295029,0.00543203,1.38765 kka2_1:4_A13M,kka2_1:4_13,Kka2,kka2_1:4,P00552,1.38776,NO,13,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.248,-3.735,1.487,,0.689,G,A,0.46,0.99,,,92.05,OHH,-1.646,0.168804,0.00784241,1.38776 kka2_1:2_R143A,kka2_1:2_143,Kka2,kka2_1:2,P00552,1.38777,NO,143,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.525,-2.1,-0.425,,0.325,H,A,0.16,1.22,14.853,14.853,65.53,ABH,-1.86833,0.295029,0.00662247,1.38777 kka2_1:4_T28Q,kka2_1:4_28,Kka2,kka2_1:4,P00552,1.38784,NO,28,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.883,-4.073,2.19,,0.353,S,B,0.82,2.02,4.415,,63.64,PPH,-1.74467,0.168804,0.00743084,1.38784 beta-lactamase_0_K190V,beta-lactamase_0_190,TEM-1,beta-lactamase_0,P62593,1.38829,NO,190,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-1.994,-2.992,0.998,,0.371,H,A,2.34,0.16,16.606,16.606,77.62,BBH,-1.64167,0.0500837,0.00574527,1.38829 kka2_1:4_V153I,kka2_1:4_153,Kka2,kka2_1:4,P00552,1.38842,NO,153,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.092,-1.693,0.601,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.168804,0.00501119,1.38842 kka2_1:2_I2L,kka2_1:2_2,Kka2,kka2_1:2,P00552,1.38933,NO,2,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.787,-2.519,0.732,,,,,,,5.773,,71.59,HHA,-1.92433,0.295029,0.00246644,1.38933 kka2_1:4_G234K,kka2_1:4_234,Kka2,kka2_1:4,P00552,1.38948,NO,234,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-2.9,-2.482,-0.418,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.168804,0.00984449,1.38948 kka2_1:4_G234L,kka2_1:4_234,Kka2,kka2_1:4,P00552,1.38957,NO,234,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-2.9,-3.687,0.787,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.168804,0.00984449,1.38957 kka2_1:4_G10L,kka2_1:4_10,Kka2,kka2_1:4,P00552,1.3896,NO,10,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.921,-3.61,1.689,,,,,,,1.862,,71.59,HOP,-2.10733,0.168804,0.00289233,1.3896 kka2_1:4_S251W,kka2_1:4_251,Kka2,kka2_1:4,P00552,1.38994,NO,251,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.636,-5.587,2.951,,0.712,H,A,0.77,-0.25,,,71.59,APP,-2.09367,0.168804,0.0138916,1.38994 beta-lactamase_0_K232G,beta-lactamase_0_232,TEM-1,beta-lactamase_0,P62593,1.39002,NO,232,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.012,-3.401,2.389,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.0500837,0.00313441,1.39002 kka2_1:2_A108G,kka2_1:2_108,Kka2,kka2_1:2,P00552,1.39023,NO,108,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.061,-2.917,0.856,,0.243,.,B,0.46,-1.34,2.462,,71.59,HHO,-1.57033,0.295029,0.00751209,1.39023 beta-lactamase_0_R275I,beta-lactamase_0_275,TEM-1,beta-lactamase_0,P62593,1.39047,NO,275,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.397,-4.133,2.736,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.0500837,0.0141984,1.39047 kka2_1:4_S11C,kka2_1:4_11,Kka2,kka2_1:4,P00552,1.39059,NO,11,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.322,-4.711,2.389,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.168804,0.00381691,1.39059 kka2_1:4_A248W,kka2_1:4_248,Kka2,kka2_1:4,P00552,1.39062,NO,248,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.124,-5.601,3.477,,0.825,S,b,0.46,0.46,,,92.05,HHO,-2.15,0.168804,0.0125484,1.39062 kka2_1:4_I246M,kka2_1:4_246,Kka2,kka2_1:4,P00552,1.39071,NO,246,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-2.008,-2.785,0.777,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.168804,0.0139479,1.39071 kka2_1:2_Q155F,kka2_1:2_155,Kka2,kka2_1:2,P00552,1.39096,NO,155,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.606,-4.366,1.76,,0.525,T,A,0.64,1.49,1.592,,63.64,APA,-1.726,0.295029,0.00641853,1.39096 kka2_1:4_V242W,kka2_1:4_242,Kka2,kka2_1:4,P00552,1.39147,NO,242,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-2.687,-5.598,2.911,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.168804,0.0102575,1.39147 kka2_1:2_L7V,kka2_1:2_7,Kka2,kka2_1:2,P00552,1.39158,NO,7,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.926,-3.173,1.247,,,,,,,3.012,,71.59,OHB,-2.12333,0.295029,0.00269456,1.39158 beta-lactamase_0_T179I,beta-lactamase_0_179,TEM-1,beta-lactamase_0,P62593,1.3918,NO,179,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.085,-3.69,2.605,,,E,B,0.22,-1.38,0.367,,73.08,PPH,-1.557,0.0500837,0.00226045,1.3918 kka2_1:2_Q4T,kka2_1:2_4,Kka2,kka2_1:2,P00552,1.39237,NO,4,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.361,-3.156,0.795,,,,,,,2.026,,71.59,APA,-1.95533,0.295029,0.00239179,1.39237 kka2_1:4_R177K,kka2_1:4_177,Kka2,kka2_1:4,P00552,1.39267,NO,177,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.282,-3.03,0.748,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.168804,0.00768224,1.39267 kka2_1:4_Q42E,kka2_1:4_42,Kka2,kka2_1:4,P00552,1.39269,NO,42,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.907,-2.56,-0.347,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.168804,0.00679212,1.39269 kka2_1:2_L165T,kka2_1:2_165,Kka2,kka2_1:2,P00552,1.39288,NO,165,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-2.453,-3.066,0.613,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.295029,0.00801161,1.39288 kka2_1:2_A13Q,kka2_1:2_13,Kka2,kka2_1:2,P00552,1.39293,NO,13,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.248,-3.029,0.781,,0.689,G,A,0.46,0.99,,,92.05,OHH,-1.646,0.295029,0.00784241,1.39293 kka2_1:2_A247Q,kka2_1:2_247,Kka2,kka2_1:2,P00552,1.39307,NO,247,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.459,-3.224,0.765,,1.01,S,A,0.46,0.65,0.828,,92.05,HHH,-2.197,0.295029,0.0102428,1.39307 kka2_1:2_I2M,kka2_1:2_2,Kka2,kka2_1:2,P00552,1.39385,NO,2,I,M,IM,Hydrophobic,Hydrophobic,6.02,5.74,-0.28,10,131,149,18,166.7,162.9,-3.8,-1.787,-3.979,2.192,,,,,,,5.773,,71.59,HHA,-1.92433,0.295029,0.00246644,1.39385 kka2_1:4_L243Q,kka2_1:4_243,Kka2,kka2_1:4,P00552,1.39395,NO,243,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-2.651,-2.876,0.225,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.168804,0.00884927,1.39395 kka2_1:2_A79R,kka2_1:2_79,Kka2,kka2_1:2,P00552,1.39401,NO,79,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.368,-2.341,-0.027,,0.563,.,B,0.46,-0.43,0.475,,71.59,HHH,-1.752,0.295029,0.00664821,1.39401 kka2_1:4_A247Q,kka2_1:4_247,Kka2,kka2_1:4,P00552,1.39423,NO,247,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.459,-3.224,0.765,,1.01,S,A,0.46,0.65,,,92.05,HHH,-2.197,0.168804,0.0102428,1.39423 kka2_1:4_A168R,kka2_1:4_168,Kka2,kka2_1:4,P00552,1.39454,NO,168,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.989,-3.003,1.014,,0.67,H,A,0.46,0.15,,,64.39,OHA,-2.12933,0.168804,0.00806773,1.39454 kka2_1:4_A168G,kka2_1:4_168,Kka2,kka2_1:4,P00552,1.39458,NO,168,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-1.989,-2.951,0.962,,0.67,H,A,0.46,0.15,,,64.39,OHA,-2.12933,0.168804,0.00806773,1.39458 kka2_1:2_V16Q,kka2_1:2_16,Kka2,kka2_1:2,P00552,1.39504,NO,16,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-3.087,-2.664,-0.423,,0.742,T,A,0.44,0.34,1.746,,71.59,HHA,-2.211,0.295029,0.00694011,1.39504 kka2_1:2_G234R,kka2_1:2_234,Kka2,kka2_1:2,P00552,1.39545,NO,234,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-2.9,-3.848,0.948,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.295029,0.00984449,1.39545 beta-lactamase_0_A84E,beta-lactamase_0_84,TEM-1,beta-lactamase_0,P62593,1.39572,NO,84,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.651,-2.632,0.981,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.0500837,0.00503822,1.39572 kka2_1:4_R177L,kka2_1:4_177,Kka2,kka2_1:4,P00552,1.39586,NO,177,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-2.282,-2.255,-0.027,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.168804,0.00768224,1.39586 kka2_1:4_D238A,kka2_1:4_238,Kka2,kka2_1:4,P00552,1.396,NO,238,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.83,-1.842,-0.988,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.168804,0.0113863,1.396 kka2_1:4_R177M,kka2_1:4_177,Kka2,kka2_1:4,P00552,1.39664,NO,177,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.282,-3.296,1.014,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.168804,0.00768224,1.39664 kka2_1:4_V242T,kka2_1:4_242,Kka2,kka2_1:4,P00552,1.39665,NO,242,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-2.687,-2.522,-0.165,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.168804,0.0102575,1.39665 kka2_1:4_A108P,kka2_1:4_108,Kka2,kka2_1:4,P00552,1.39673,NO,108,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.061,-2.19,0.129,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.168804,0.00751209,1.39673 kka2_1:4_A247R,kka2_1:4_247,Kka2,kka2_1:4,P00552,1.39684,NO,247,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.459,-3.186,0.727,,1.01,S,A,0.46,0.65,,,92.05,HHH,-2.197,0.168804,0.0102428,1.39684 kka2_1:4_Q155D,kka2_1:4_155,Kka2,kka2_1:4,P00552,1.39684,NO,155,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.606,-2.377,-0.229,,0.525,T,A,0.64,1.49,1.592,,63.64,APA,-1.726,0.168804,0.00641853,1.39684 kka2_1:2_D238W,kka2_1:2_238,Kka2,kka2_1:2,P00552,1.39725,NO,238,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.83,-5.568,2.738,,0.604,H,A,0.75,-0.33,22.789,22.789,92.05,HAB,-2.633,0.295029,0.0113863,1.39725 kka2_1:4_Q252N,kka2_1:4_252,Kka2,kka2_1:4,P00552,1.39746,NO,252,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.63,-3.762,1.132,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.168804,0.0121001,1.39746 kka2_1:4_H139F,kka2_1:4_139,Kka2,kka2_1:4,P00552,1.39751,NO,139,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-2.809,-3.506,0.697,,0.471,H,A,0.17,0.68,12.761,12.761,63.64,BBB,-2.22,0.168804,0.00734779,1.39751 kka2_1:2_Q163L,kka2_1:2_163,Kka2,kka2_1:2,P00552,1.39773,NO,163,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.162,-1.74,-0.422,,0.58,T,B,0.64,1.85,3.888,,64.02,BPO,-1.78333,0.295029,0.00719507,1.39773 kka2_1:2_A35Q,kka2_1:2_35,Kka2,kka2_1:2,P00552,1.39788,NO,35,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.127,-3.255,1.128,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.295029,0.00630016,1.39788 kka2_1:2_H106E,kka2_1:2_106,Kka2,kka2_1:2,P00552,1.39797,NO,106,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-3.13,-2.347,-0.783,,1.065,.,a,0.17,-0.95,2.53,,71.59,PBH,-2.10433,0.295029,0.00730778,1.39797 kka2_1:4_K175C,kka2_1:4_175,Kka2,kka2_1:4,P00552,1.39813,NO,175,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-2.897,-2.882,-0.015,,0.579,H,A,1.3,0.51,15.629,15.629,71.59,HBH,-1.82333,0.168804,0.00693093,1.39813 kka2_1:4_H8D,kka2_1:4_8,Kka2,kka2_1:4,P00552,1.39816,NO,8,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-2.759,-3.533,0.774,,,,,,,,,71.59,HBH,-2.25467,0.168804,0.00256422,1.39816 kka2_1:4_H8F,kka2_1:4_8,Kka2,kka2_1:4,P00552,1.39867,NO,8,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-2.759,-4.004,1.245,,,,,,,,,71.59,HBH,-2.25467,0.168804,0.00256422,1.39867 kka2_1:4_F20D,kka2_1:4_20,Kka2,kka2_1:4,P00552,1.39892,NO,20,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-3.354,-3.734,0.38,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.168804,0.00701744,1.39892 kka2_1:4_S251M,kka2_1:4_251,Kka2,kka2_1:4,P00552,1.3991,NO,251,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.636,-4.807,2.171,,0.712,H,A,0.77,-0.25,,,71.59,APP,-2.09367,0.168804,0.0138916,1.3991 kka2_1:4_I2T,kka2_1:4_2,Kka2,kka2_1:4,P00552,1.39994,NO,2,I,T,IT,Hydrophobic,Polar,6.02,5.6,-0.42,89,131,119,-12,166.7,116.1,-50.6,-1.787,-2.02,0.233,,,,,,,,,71.59,HHA,-1.92433,0.168804,0.00246644,1.39994 kka2_1:2_L165V,kka2_1:2_165,Kka2,kka2_1:2,P00552,1.40034,NO,165,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-2.453,-2.841,0.388,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.295029,0.00801161,1.40034 kka2_1:2_V46A,kka2_1:2_46,Kka2,kka2_1:2,P00552,1.40065,NO,46,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-2.62,-2.194,-0.426,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.295029,0.00631301,1.40065 beta-lactamase_0_D212S,beta-lactamase_0_212,TEM-1,beta-lactamase_0,P62593,1.40112,NO,212,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.624,-2.471,0.847,,0.037,,b,0.75,-0.58,3.34,,74.48,HAB,-1.77667,0.0500837,0.00644302,1.40112 kka2_1:2_D118E,kka2_1:2_118,Kka2,kka2_1:2,P00552,1.40134,NO,118,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.07,-2.401,0.331,,0.61,H,A,0.75,-0.05,2.237,,64.39,HAH,-1.32367,0.295029,0.0067852,1.40134 kka2_1:2_G234H,kka2_1:2_234,Kka2,kka2_1:2,P00552,1.40146,NO,234,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-2.9,-4.698,1.798,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.295029,0.00984449,1.40146 kka2_1:4_A168Q,kka2_1:4_168,Kka2,kka2_1:4,P00552,1.40157,NO,168,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.989,-2.544,0.555,,0.67,H,A,0.46,0.15,,,64.39,OHA,-2.12933,0.168804,0.00806773,1.40157 beta-lactamase_0_A132E,beta-lactamase_0_132,TEM-1,beta-lactamase_0,P62593,1.40171,NO,132,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-0.9,-3.484,2.584,,,H,A,0.46,-0.93,2.249,,64.69,PHH,-1.138,0.0500837,0.000962524,1.40171 kka2_1:2_T125G,kka2_1:2_125,Kka2,kka2_1:2,P00552,1.40191,NO,125,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.622,-2.508,-0.114,,0.791,T,A,0.22,0.33,2.029,,92.05,BPH,-1.56933,0.295029,0.00821755,1.40191 beta-lactamase_0_E272Y,beta-lactamase_0_272,TEM-1,beta-lactamase_0,P62593,1.40207,NO,272,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.0500837,0.00545371,1.40207 kka2_1:2_D23Q,kka2_1:2_23,Kka2,kka2_1:2,P00552,1.40207,NO,23,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.459,-3.078,0.619,,0.695,E,B,0.75,-0.65,18.207,18.207,65.53,HAH,-1.94033,0.295029,0.007195,1.40207 kka2_1:8_D238K,kka2_1:8_238,Kka2,kka2_1:8,P00552,1.40234,NO,238,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.83,-2.641,-0.189,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.100394,0.0113863,1.40234 kka2_1:8_D238K,kka2_1:8_238,Kka2,kka2_1:8,P00552,1.40234,NO,238,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.83,-2.641,-0.189,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.100394,0.0113863,1.40234 kka2_1:2_G6Q,kka2_1:2_6,Kka2,kka2_1:2,P00552,1.40255,NO,6,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.685,-3.809,2.124,,,,,,,,,71.59,AOH,-1.639,0.295029,0.00204693,1.40255 kka2_1:4_R173E,kka2_1:4_173,Kka2,kka2_1:4,P00552,1.40274,NO,173,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.407,-1.731,-0.676,,0.308,H,A,1.2,-0.13,1.777,,65.53,HBH,-1.70533,0.168804,0.00784999,1.40274 beta-lactamase_0_D212P,beta-lactamase_0_212,TEM-1,beta-lactamase_0,P62593,1.40314,NO,212,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.624,-3.916,2.292,,0.037,,b,0.75,-0.58,3.34,,74.48,HAB,-1.77667,0.0500837,0.00644302,1.40314 kka2_1:2_Q27M,kka2_1:2_27,Kka2,kka2_1:2,P00552,1.40326,NO,27,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-1.659,-3.318,1.659,,0.608,.,A,0.64,0.71,0.521,,65.53,PPP,-1.90733,0.295029,0.00595365,1.40326 beta-lactamase_0_E119W,beta-lactamase_0_119,TEM-1,beta-lactamase_0,P62593,1.40357,NO,119,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.412,-5.452,4.04,,0.358,H,A,1.04,0.51,3.396,,63.99,BAH,-1.623,0.0500837,0.00386966,1.40357 beta-lactamase_0_H110Y,beta-lactamase_0_110,TEM-1,beta-lactamase_0,P62593,1.40382,NO,110,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-1.706,-2.513,0.807,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.0500837,0.00441499,1.40382 kka2_1:2_A166T,kka2_1:2_166,Kka2,kka2_1:2,P00552,1.40435,NO,166,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.407,-1.912,-0.495,,0.534,.,B,0.46,1.03,23.175,23.175,71.59,HHO,-2.421,0.295029,0.00799912,1.40435 kka2_1:4_A35L,kka2_1:4_35,Kka2,kka2_1:4,P00552,1.4048,NO,35,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.127,-3.045,0.918,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.168804,0.00630016,1.4048 kka2_1:4_A14Q,kka2_1:4_14,Kka2,kka2_1:4,P00552,1.40529,NO,14,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.837,-2.773,0.936,,0.728,G,A,0.46,0.7,0.36,,71.59,HHH,-1.82567,0.168804,0.00706614,1.40529 kka2_1:4_D5N,kka2_1:4_5,Kka2,kka2_1:4,P00552,1.40592,NO,5,D,N,DN,negativeCharge,Polar,5.0516,5.47157,0.419975,23,133,132,-1,111.1,114.1,3,-1.306,-3.103,1.797,,,,,,,,,71.59,PAO,-1.784,0.168804,0.00222864,1.40592 kka2_1:2_P45K,kka2_1:2_45,Kka2,kka2_1:2,P00552,1.40606,NO,45,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.774,-2.635,0.861,,0.669,,B,0.52,-0.76,4.882,,71.59,BOH,-2.152,0.295029,0.00590481,1.40606 kka2_1:4_D5F,kka2_1:4_5,Kka2,kka2_1:4,P00552,1.4061,NO,5,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.306,-4.103,2.797,,,,,,,,,71.59,PAO,-1.784,0.168804,0.00222864,1.4061 kka2_1:2_I2V,kka2_1:2_2,Kka2,kka2_1:2,P00552,1.40658,NO,2,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.787,-1.838,0.051,,,,,,,5.773,,71.59,HHA,-1.92433,0.295029,0.00246644,1.40658 kka2_1:2_T225M,kka2_1:2_225,Kka2,kka2_1:2,P00552,1.40662,NO,225,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.393,-3.418,1.025,,0.036,H,A,0.22,-1.22,4.554,,63.64,HPB,-1.58733,0.295029,0.0113598,1.40662 kka2_1:4_D52V,kka2_1:4_52,Kka2,kka2_1:4,P00552,1.40716,NO,52,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.271,-3.601,1.33,,0.22,E,B,0.75,0.8,0.349,,71.59,PAH,-2.38367,0.168804,0.00175694,1.40716 kka2_1:4_Q4I,kka2_1:4_4,Kka2,kka2_1:4,P00552,1.40729,NO,4,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.361,-3.887,1.526,,,,,,,2.026,,71.59,APA,-1.95533,0.168804,0.00239179,1.40729 kka2_1:2_G234D,kka2_1:2_234,Kka2,kka2_1:2,P00552,1.40744,NO,234,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-2.9,-2.299,-0.601,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.295029,0.00984449,1.40744 kka2_1:4_E3F,kka2_1:4_3,Kka2,kka2_1:4,P00552,1.40766,NO,3,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.199,-3.772,1.573,,,,,,,7.22,,92.05,HAP,-2.11567,0.168804,0.00267607,1.40766 kka2_1:4_F20M,kka2_1:4_20,Kka2,kka2_1:4,P00552,1.40772,NO,20,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-3.354,-4.754,1.4,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.168804,0.00701744,1.40772 kka2_1:2_V242T,kka2_1:2_242,Kka2,kka2_1:2,P00552,1.40835,NO,242,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-2.687,-2.522,-0.165,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.295029,0.0102575,1.40835 beta-lactamase_0_A132H,beta-lactamase_0_132,TEM-1,beta-lactamase_0,P62593,1.40904,NO,132,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.9,-4.724,3.824,,,H,A,0.46,-0.93,2.249,,64.69,PHH,-1.138,0.0500837,0.000962524,1.40904 kka2_1:4_D5H,kka2_1:4_5,Kka2,kka2_1:4,P00552,1.4093,NO,5,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-1.306,-4.185,2.879,,,,,,,,,71.59,PAO,-1.784,0.168804,0.00222864,1.4093 kka2_1:4_A248R,kka2_1:4_248,Kka2,kka2_1:4,P00552,1.40969,NO,248,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.124,-2.856,0.732,,0.825,S,b,0.46,0.46,,,92.05,HHO,-2.15,0.168804,0.0125484,1.40969 kka2_1:4_K175I,kka2_1:4_175,Kka2,kka2_1:4,P00552,1.40985,NO,175,K,I,KI,PositiveCharge,Hydrophobic,9.74,6.02,-3.72,102,146,131,-15,168.6,166.7,-1.9,-2.897,-2.932,0.035,,0.579,H,A,1.3,0.51,15.629,15.629,71.59,HBH,-1.82333,0.168804,0.00693093,1.40985 kka2_1:4_A247N,kka2_1:4_247,Kka2,kka2_1:4,P00552,1.40993,NO,247,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.459,-3.859,1.4,,1.01,S,A,0.46,0.65,,,92.05,HHH,-2.197,0.168804,0.0102428,1.40993 kka2_1:2_S114Q,kka2_1:2_114,Kka2,kka2_1:2,P00552,1.41025,NO,114,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.527,-3.268,0.741,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.295029,0.00705262,1.41025 kka2_1:4_E17L,kka2_1:4_17,Kka2,kka2_1:4,P00552,1.4103,NO,17,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-2.154,-3.123,0.969,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.168804,0.00688738,1.4103 kka2_1:4_Y244M,kka2_1:4_244,Kka2,kka2_1:4,P00552,1.41064,NO,244,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-0.775,-4.508,3.733,,0.066,H,A,0.21,-0.64,,,,HHO,-1.41267,0.168804,0.00453187,1.41064 kka2_1:8_E199M,kka2_1:8_199,Kka2,kka2_1:8,P00552,1.41074,NO,199,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.234,-4.802,2.568,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.100394,0.00854122,1.41074 kka2_1:8_E199M,kka2_1:8_199,Kka2,kka2_1:8,P00552,1.41074,NO,199,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.234,-4.802,2.568,,0.508,E,B,1.04,-0.43,1.519,,65.53,HAP,-2.133,0.100394,0.00854122,1.41074 kka2_1:4_Q4T,kka2_1:4_4,Kka2,kka2_1:4,P00552,1.41088,NO,4,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.361,-3.156,0.795,,,,,,,2.026,,71.59,APA,-1.95533,0.168804,0.00239179,1.41088 kka2_1:2_E3C,kka2_1:2_3,Kka2,kka2_1:2,P00552,1.41107,NO,3,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.199,-4.909,2.71,,,,,,,7.22,,92.05,HAP,-2.11567,0.295029,0.00267607,1.41107 kka2_1:4_I2F,kka2_1:4_2,Kka2,kka2_1:4,P00552,1.41169,NO,2,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.787,-3.633,1.846,,,,,,,,,71.59,HHA,-1.92433,0.168804,0.00246644,1.41169 kka2_1:4_R177E,kka2_1:4_177,Kka2,kka2_1:4,P00552,1.41182,NO,177,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.282,-2.717,0.435,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.168804,0.00768224,1.41182 kka2_1:2_D238C,kka2_1:2_238,Kka2,kka2_1:2,P00552,1.41269,NO,238,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.83,-5.149,2.319,,0.604,H,A,0.75,-0.33,22.789,22.789,92.05,HAB,-2.633,0.295029,0.0113863,1.41269 kka2_1:4_D23K,kka2_1:4_23,Kka2,kka2_1:4,P00552,1.41286,NO,23,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.459,-3.049,0.59,,0.695,E,B,0.75,-0.65,2.416,,65.53,HAH,-1.94033,0.168804,0.007195,1.41286 kka2_1:4_S40Y,kka2_1:4_40,Kka2,kka2_1:4,P00552,1.41339,NO,40,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.645,-4.369,1.724,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.168804,0.00693477,1.41339 beta-lactamase_0_V214Q,beta-lactamase_0_214,TEM-1,beta-lactamase_0,P62593,1.41392,NO,214,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.299,-4.141,2.842,,0.375,S,A,0.44,-0.44,3.712,,74.48,BHH,-1.53733,0.0500837,0.00628442,1.41392 kka2_1:4_A13D,kka2_1:4_13,Kka2,kka2_1:4,P00552,1.41401,NO,13,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.248,-2.729,0.481,,0.689,G,A,0.46,0.99,,,92.05,OHH,-1.646,0.168804,0.00784241,1.41401 kka2_1:4_A176R,kka2_1:4_176,Kka2,kka2_1:4,P00552,1.41429,NO,176,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.621,-2.52,0.899,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.168804,0.0083587,1.41429 beta-lactamase_0_E210G,beta-lactamase_0_210,TEM-1,beta-lactamase_0,P62593,1.41443,NO,210,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-2.319,-3.66,1.341,,0.476,H,A,1.04,0.75,3.618,,77.62,HAH,-1.88567,0.0500837,0.00663582,1.41443 kka2_1:4_V242M,kka2_1:4_242,Kka2,kka2_1:4,P00552,1.41466,NO,242,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-2.687,-4.779,2.092,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.168804,0.0102575,1.41466 beta-lactamase_0_E272M,beta-lactamase_0_272,TEM-1,beta-lactamase_0,P62593,1.41472,NO,272,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.0500837,0.00545371,1.41472 kka2_1:2_V153M,kka2_1:2_153,Kka2,kka2_1:2,P00552,1.41477,NO,153,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.092,-4.165,3.073,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.295029,0.00501119,1.41477 kka2_1:4_Q163M,kka2_1:4_163,Kka2,kka2_1:4,P00552,1.4148,NO,163,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.162,-2.88,0.718,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.168804,0.00719507,1.4148 kka2_1:4_A248P,kka2_1:4_248,Kka2,kka2_1:4,P00552,1.41487,NO,248,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.124,-3.022,0.898,,0.825,S,b,0.46,0.46,,,92.05,HHO,-2.15,0.168804,0.0125484,1.41487 kka2_1:2_E3I,kka2_1:2_3,Kka2,kka2_1:2,P00552,1.41529,NO,3,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.199,-3.832,1.633,,,,,,,7.22,,92.05,HAP,-2.11567,0.295029,0.00267607,1.41529 beta-lactamase_0_S122P,beta-lactamase_0_122,TEM-1,beta-lactamase_0,P62593,1.41531,NO,122,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.406,-4.011,1.605,,0.352,H,A,0.27,-0.54,30.794,30.794,77.62,OPH,-1.39767,0.0500837,0.00497825,1.41531 kka2_1:4_A166T,kka2_1:4_166,Kka2,kka2_1:4,P00552,1.41546,NO,166,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.407,-1.912,-0.495,,0.534,.,B,0.46,1.03,,,71.59,HHO,-2.421,0.168804,0.00799912,1.41546 beta-lactamase_0_T126S,beta-lactamase_0_126,TEM-1,beta-lactamase_0,P62593,1.41558,NO,126,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-1.122,-2.464,1.342,,0.05,H,A,0.22,-0.05,0.705,,44.41,HPH,-1.60467,0.0500837,0.00244552,1.41558 kka2_1:4_R177H,kka2_1:4_177,Kka2,kka2_1:4,P00552,1.41626,NO,177,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.282,-3.561,1.279,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.168804,0.00768224,1.41626 kka2_1:2_F20Y,kka2_1:2_20,Kka2,kka2_1:2,P00552,1.41652,NO,20,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-3.354,-4.354,1,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.295029,0.00701744,1.41652 beta-lactamase_0_M127C,beta-lactamase_0_127,TEM-1,beta-lactamase_0,P62593,1.41699,NO,127,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-2.251,-5.009,2.758,,0.312,S,A,0.55,0.32,9.35,9.35,72.73,PHP,-1.40433,0.0500837,0.00437927,1.41699 kka2_1:2_Q42E,kka2_1:2_42,Kka2,kka2_1:2,P00552,1.41707,NO,42,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.907,-2.56,-0.347,,1.044,T,B,0.64,-0.8,2.792,,71.59,HPO,-2.12433,0.295029,0.00679212,1.41707 kka2_1:4_I2H,kka2_1:4_2,Kka2,kka2_1:4,P00552,1.41717,NO,2,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.787,-4.676,2.889,,,,,,,,,71.59,HHA,-1.92433,0.168804,0.00246644,1.41717 kka2_1:2_G43E,kka2_1:2_43,Kka2,kka2_1:2,P00552,1.41731,NO,43,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.587,-2.715,1.128,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.295029,0.0071925,1.41731 kka2_1:2_V46C,kka2_1:2_46,Kka2,kka2_1:2,P00552,1.4176,NO,46,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-2.62,-3.346,0.726,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.295029,0.00631301,1.4176 beta-lactamase_0_T131Y,beta-lactamase_0_131,TEM-1,beta-lactamase_0,P62593,1.41809,NO,131,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.328,-4.285,2.957,,,H,A,0.22,-0.69,3.306,,67.48,PPH,-1.00867,0.0500837,0.00345886,1.41809 kka2_1:4_I2Y,kka2_1:4_2,Kka2,kka2_1:4,P00552,1.4182,NO,2,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.787,-3.837,2.05,,,,,,,,,71.59,HHA,-1.92433,0.168804,0.00246644,1.4182 kka2_1:2_A166H,kka2_1:2_166,Kka2,kka2_1:2,P00552,1.41842,NO,166,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.407,-4.764,2.357,,0.534,.,B,0.46,1.03,23.175,23.175,71.59,HHO,-2.421,0.295029,0.00799912,1.41842 kka2_1:2_Q4P,kka2_1:2_4,Kka2,kka2_1:2,P00552,1.41942,NO,4,Q,P,QP,Polar,Special,6.24429,6.3,0.0557143,76,146,115,-31,143.8,112.7,-31.1,-2.361,-3.662,1.301,,,,,,,2.026,,71.59,APA,-1.95533,0.295029,0.00239179,1.41942 kka2_1:2_V46P,kka2_1:2_46,Kka2,kka2_1:2,P00552,1.41945,NO,46,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-2.62,-2.348,-0.272,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.295029,0.00631301,1.41945 kka2_1:2_T146M,kka2_1:2_146,Kka2,kka2_1:2,P00552,1.41956,NO,146,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.978,-3.5,0.522,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.295029,0.00606474,1.41956 kka2_1:4_Q163F,kka2_1:4_163,Kka2,kka2_1:4,P00552,1.42004,NO,163,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.162,-4.196,2.034,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.168804,0.00719507,1.42004 kka2_1:4_Q136S,kka2_1:4_136,Kka2,kka2_1:4,P00552,1.42072,NO,136,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-3.021,-2.294,-0.727,,0.331,.,b,0.64,0.96,23.8,23.8,92.05,BPH,-2.16933,0.168804,0.00624149,1.42072 kka2_1:4_E235H,kka2_1:4_235,Kka2,kka2_1:4,P00552,1.42078,NO,235,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.955,-4.699,2.744,,0.631,H,A,1.04,0.12,23.175,23.175,65.53,OAH,-2.07267,0.168804,0.0102806,1.42078 kka2_1:4_A248K,kka2_1:4_248,Kka2,kka2_1:4,P00552,1.42119,NO,248,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.124,-2.875,0.751,,0.825,S,b,0.46,0.46,,,92.05,HHO,-2.15,0.168804,0.0125484,1.42119 kka2_1:4_Q155Y,kka2_1:4_155,Kka2,kka2_1:4,P00552,1.42133,NO,155,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.606,-4.298,1.692,,0.525,T,A,0.64,1.49,1.592,,63.64,APA,-1.726,0.168804,0.00641853,1.42133 beta-lactamase_0_Q267Y,beta-lactamase_0_267,TEM-1,beta-lactamase_0,P62593,1.42197,NO,267,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.308,,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.0500837,0.0102128,1.42197 kka2_1:4_G234I,kka2_1:4_234,Kka2,kka2_1:4,P00552,1.42308,NO,234,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-2.9,-4.067,1.167,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.168804,0.00984449,1.42308 kka2_1:4_H8E,kka2_1:4_8,Kka2,kka2_1:4,P00552,1.4231,NO,8,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-2.759,-3.378,0.619,,,,,,,,,71.59,HBH,-2.25467,0.168804,0.00256422,1.4231 kka2_1:4_I2V,kka2_1:4_2,Kka2,kka2_1:4,P00552,1.42427,NO,2,I,V,IV,Hydrophobic,Hydrophobic,6.02,5.60847,-0.411535,29,131,117,-14,166.7,140,-26.7,-1.787,-1.838,0.051,,,,,,,,,71.59,HHA,-1.92433,0.168804,0.00246644,1.42427 kka2_1:4_S251K,kka2_1:4_251,Kka2,kka2_1:4,P00552,1.42431,NO,251,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.636,-3.007,0.371,,0.712,H,A,0.77,-0.25,,,71.59,APP,-2.09367,0.168804,0.0138916,1.42431 kka2_1:4_G6M,kka2_1:4_6,Kka2,kka2_1:4,P00552,1.42434,NO,6,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.685,-4.549,2.864,,,,,,,,,71.59,AOH,-1.639,0.168804,0.00204693,1.42434 kka2_1:8_Q163M,kka2_1:8_163,Kka2,kka2_1:8,P00552,1.42482,NO,163,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.162,-2.88,0.718,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.100394,0.00719507,1.42482 kka2_1:8_Q163M,kka2_1:8_163,Kka2,kka2_1:8,P00552,1.42482,NO,163,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.162,-2.88,0.718,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.100394,0.00719507,1.42482 kka2_1:2_G6D,kka2_1:2_6,Kka2,kka2_1:2,P00552,1.42486,NO,6,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.685,-3.441,1.756,,,,,,,,,71.59,AOH,-1.639,0.295029,0.00204693,1.42486 beta-lactamase_0_L100H,beta-lactamase_0_100,TEM-1,beta-lactamase_0,P62593,1.42539,NO,100,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.218,-4.855,3.637,,0.343,,B,0.55,0.13,1.373,,63.29,AHH,-1.23467,0.0500837,0.00413885,1.42539 beta-lactamase_0_I285C,beta-lactamase_0_285,TEM-1,beta-lactamase_0,P62593,1.42615,NO,285,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.845,,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.0500837,0.101555,1.42615 kka2_1:2_D238H,kka2_1:2_238,Kka2,kka2_1:2,P00552,1.42624,NO,238,D,H,DH,negativeCharge,PositiveCharge,5.0516,7.59,2.5384,81,133,155,22,111.1,153.2,42.1,-2.83,-4.728,1.898,,0.604,H,A,0.75,-0.33,22.789,22.789,92.05,HAB,-2.633,0.295029,0.0113863,1.42624 kka2_1:2_L7K,kka2_1:2_7,Kka2,kka2_1:2,P00552,1.42642,NO,7,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.926,-3.481,1.555,,,,,,,3.012,,71.59,OHB,-2.12333,0.295029,0.00269456,1.42642 kka2_1:2_R173A,kka2_1:2_173,Kka2,kka2_1:2,P00552,1.42656,NO,173,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.407,-2.391,-0.016,,0.308,H,A,0.16,-0.13,15.389,15.389,65.53,HBH,-1.70533,0.295029,0.00784999,1.42656 kka2_1:4_A9P,kka2_1:4_9,Kka2,kka2_1:4,P00552,1.42664,NO,9,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.079,-2.571,0.492,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.168804,0.00273264,1.42664 kka2_1:4_S11L,kka2_1:4_11,Kka2,kka2_1:4,P00552,1.42674,NO,11,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.322,-1.799,-0.523,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.168804,0.00381691,1.42674 kka2_1:8_D23K,kka2_1:8_23,Kka2,kka2_1:8,P00552,1.42753,NO,23,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.459,-3.049,0.59,,0.695,E,B,0.75,-0.65,,,65.53,HAH,-1.94033,0.100394,0.007195,1.42753 kka2_1:8_D23K,kka2_1:8_23,Kka2,kka2_1:8,P00552,1.42753,NO,23,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-2.459,-3.049,0.59,,0.695,E,B,0.75,-0.65,,,65.53,HAH,-1.94033,0.100394,0.007195,1.42753 kka2_1:2_D238E,kka2_1:2_238,Kka2,kka2_1:2,P00552,1.42825,NO,238,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,-2.83,-2.206,-0.624,,0.604,H,A,0.75,-0.33,22.789,22.789,92.05,HAB,-2.633,0.295029,0.0113863,1.42825 kka2_1:4_G43E,kka2_1:4_43,Kka2,kka2_1:4,P00552,1.4283,NO,43,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.587,-2.715,1.128,,0.862,T,l,0.75,-0.67,2.247,,63.26,POB,-2.18533,0.168804,0.0071925,1.4283 kka2_1:4_R253K,kka2_1:4_253,Kka2,kka2_1:4,P00552,1.42881,NO,253,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.356,-1.563,0.207,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.168804,0.0144195,1.42881 beta-lactamase_0_D129I,beta-lactamase_0_129,TEM-1,beta-lactamase_0,P62593,1.42889,NO,129,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-0.816,-4.036,3.22,,,,B,0.75,-0.69,2.66,,34.97,PAP,-0.818,0.0500837,0.00109178,1.42889 beta-lactamase_0_P105M,beta-lactamase_0_105,TEM-1,beta-lactamase_0,P62593,1.42953,NO,105,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-0.813,-4.702,3.889,,0.226,T,A,0.52,0.8,3.48,,63.29,POH,-1.01533,0.0500837,0.0011981,1.42953 kka2_1:2_S251V,kka2_1:2_251,Kka2,kka2_1:2,P00552,1.42972,NO,251,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.636,-3.716,1.08,,0.712,H,A,0.27,-0.25,32.832,32.832,71.59,APP,-2.09367,0.295029,0.0138916,1.42972 kka2_1:4_T225M,kka2_1:4_225,Kka2,kka2_1:4,P00552,1.43003,NO,225,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-2.393,-3.418,1.025,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.168804,0.0113598,1.43003 kka2_1:2_Q252E,kka2_1:2_252,Kka2,kka2_1:2,P00552,1.43036,NO,252,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.63,-1.971,-0.659,,0.906,H,A,0.64,0.35,5.613,,92.05,PPB,-2.20733,0.295029,0.0121001,1.43036 kka2_1:2_A108P,kka2_1:2_108,Kka2,kka2_1:2,P00552,1.43097,NO,108,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.061,-2.19,0.129,,0.243,.,B,0.46,-1.34,2.462,,71.59,HHO,-1.57033,0.295029,0.00751209,1.43097 kka2_1:2_A14Q,kka2_1:2_14,Kka2,kka2_1:2,P00552,1.43163,NO,14,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.837,-2.773,0.936,,0.728,G,A,0.46,0.7,0.36,,71.59,HHH,-1.82567,0.295029,0.00706614,1.43163 kka2_1:2_V16G,kka2_1:2_16,Kka2,kka2_1:2,P00552,1.43184,NO,16,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-3.087,-2.751,-0.336,,0.742,T,A,0.44,0.34,1.746,,71.59,HHA,-2.211,0.295029,0.00694011,1.43184 kka2_1:4_D5S,kka2_1:4_5,Kka2,kka2_1:4,P00552,1.43184,NO,5,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.306,-2.972,1.666,,,,,,,,,71.59,PAO,-1.784,0.168804,0.00222864,1.43184 kka2_1:4_E149V,kka2_1:4_149,Kka2,kka2_1:4,P00552,1.43213,NO,149,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.994,-3.648,1.654,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.168804,0.00803343,1.43213 kka2_1:4_S251V,kka2_1:4_251,Kka2,kka2_1:4,P00552,1.43217,NO,251,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.636,-3.716,1.08,,0.712,H,A,0.77,-0.25,,,71.59,APP,-2.09367,0.168804,0.0138916,1.43217 kka2_1:2_A247D,kka2_1:2_247,Kka2,kka2_1:2,P00552,1.43222,NO,247,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.459,-3.029,0.57,,1.01,S,A,0.46,0.65,0.828,,92.05,HHH,-2.197,0.295029,0.0102428,1.43222 kka2_1:4_L165T,kka2_1:4_165,Kka2,kka2_1:4,P00552,1.43227,NO,165,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-2.453,-3.066,0.613,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.168804,0.00801161,1.43227 kka2_1:2_I2H,kka2_1:2_2,Kka2,kka2_1:2,P00552,1.43343,NO,2,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.787,-4.676,2.889,,,,,,,5.773,,71.59,HHA,-1.92433,0.295029,0.00246644,1.43343 beta-lactamase_0_A132D,beta-lactamase_0_132,TEM-1,beta-lactamase_0,P62593,1.43377,NO,132,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.9,-3.706,2.806,,,H,A,0.46,-0.93,2.249,,64.69,PHH,-1.138,0.0500837,0.000962524,1.43377 beta-lactamase_0_R41W,beta-lactamase_0_41,TEM-1,beta-lactamase_0,P62593,1.43399,NO,41,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-0.942,-5.348,4.406,,0.321,E,B,1.2,-0.07,2.68,,65.03,HBH,-1.30267,0.0500837,0.00123327,1.43399 kka2_1:4_I221L,kka2_1:4_221,Kka2,kka2_1:4,P00552,1.43492,NO,221,I,L,IL,Hydrophobic,Hydrophobic,6.02,9.7088,3.6888,5,131,131,0,166.7,166.7,0,-1.739,-1.153,-0.586,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.168804,0.00945908,1.43492 kka2_1:4_L243E,kka2_1:4_243,Kka2,kka2_1:4,P00552,1.43509,NO,243,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-2.651,-2.717,0.066,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.168804,0.00884927,1.43509 kka2_1:4_R177I,kka2_1:4_177,Kka2,kka2_1:4,P00552,1.4351,NO,177,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.282,-3.929,1.647,,0.521,T,A,1.2,0.16,,,63.64,HBH,-2.36967,0.168804,0.00768224,1.4351 beta-lactamase_0_V29D,beta-lactamase_0_29,TEM-1,beta-lactamase_0,P62593,1.4353,NO,29,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-2.856,-2.298,-0.558,,0.733,H,A,0.44,-0.78,21.916,21.916,93.01,HHB,-2.24733,0.0500837,0.00318969,1.4353 kka2_1:4_G10P,kka2_1:4_10,Kka2,kka2_1:4,P00552,1.43577,NO,10,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.921,-2.317,0.396,,,,,,,1.862,,71.59,HOP,-2.10733,0.168804,0.00289233,1.43577 kka2_1:4_A247M,kka2_1:4_247,Kka2,kka2_1:4,P00552,1.43604,NO,247,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.459,-3.49,1.031,,1.01,S,A,0.46,0.65,,,92.05,HHH,-2.197,0.168804,0.0102428,1.43604 kka2_1:4_E235Y,kka2_1:4_235,Kka2,kka2_1:4,P00552,1.43753,NO,235,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.955,-4.43,2.475,,0.631,H,A,1.04,0.12,23.175,23.175,65.53,OAH,-2.07267,0.168804,0.0102806,1.43753 kka2_1:4_S40T,kka2_1:4_40,Kka2,kka2_1:4,P00552,1.43797,NO,40,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.645,-2.259,-0.386,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.168804,0.00693477,1.43797 kka2_1:2_H106K,kka2_1:2_106,Kka2,kka2_1:2,P00552,1.43865,NO,106,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-3.13,-3.67,0.54,,1.065,.,a,0.17,-0.95,2.53,,71.59,PBH,-2.10433,0.295029,0.00730778,1.43865 kka2_1:4_S251E,kka2_1:4_251,Kka2,kka2_1:4,P00552,1.43938,NO,251,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.636,-2.355,-0.281,,0.712,H,A,0.77,-0.25,,,71.59,APP,-2.09367,0.168804,0.0138916,1.43938 kka2_1:2_F20M,kka2_1:2_20,Kka2,kka2_1:2,P00552,1.43967,NO,20,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-3.354,-4.754,1.4,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.295029,0.00701744,1.43967 kka2_1:4_E160Y,kka2_1:4_160,Kka2,kka2_1:4,P00552,1.44037,NO,160,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.683,-4.448,2.765,,0.989,G,A,1.04,2.28,2.531,,71.59,AAA,-1.36133,0.168804,0.00935762,1.44037 beta-lactamase_0_R92Y,beta-lactamase_0_92,TEM-1,beta-lactamase_0,P62593,1.44058,NO,92,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.718,-4.31,2.592,,0.479,E,B,1.2,1.36,2.331,,65.38,BBH,-1.50367,0.0500837,0.00429626,1.44058 kka2_1:2_R143V,kka2_1:2_143,Kka2,kka2_1:2,P00552,1.44297,NO,143,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.525,-2.516,-0.009,,0.325,H,A,0.16,1.22,14.853,14.853,65.53,ABH,-1.86833,0.295029,0.00662247,1.44297 kka2_1:4_V242C,kka2_1:4_242,Kka2,kka2_1:4,P00552,1.44339,NO,242,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-2.687,-5.161,2.474,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.168804,0.0102575,1.44339 kka2_1:2_T125S,kka2_1:2_125,Kka2,kka2_1:2,P00552,1.44345,NO,125,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.622,-2.445,-0.177,,0.791,T,A,0.22,0.33,2.029,,92.05,BPH,-1.56933,0.295029,0.00821755,1.44345 kka2_1:4_L158Y,kka2_1:4_158,Kka2,kka2_1:4,P00552,1.445,NO,158,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.947,-3.398,1.451,,0.095,,B,1.59,0.77,7.588,,63.64,AHA,-1.25333,0.168804,0.00529068,1.445 kka2_1:2_F20S,kka2_1:2_20,Kka2,kka2_1:2,P00552,1.44521,NO,20,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-3.354,-2.147,-1.207,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.295029,0.00701744,1.44521 kka2_1:8_G6P,kka2_1:8_6,Kka2,kka2_1:8,P00552,1.44589,NO,6,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.685,-2.187,0.502,,,,,,,,,71.59,AOH,-1.639,0.100394,0.00204693,1.44589 kka2_1:8_G6P,kka2_1:8_6,Kka2,kka2_1:8,P00552,1.44589,NO,6,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.685,-2.187,0.502,,,,,,,,,71.59,AOH,-1.639,0.100394,0.00204693,1.44589 kka2_1:2_L53R,kka2_1:2_53,Kka2,kka2_1:2,P00552,1.44598,NO,53,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-2.681,-2.891,0.21,,0.569,E,B,0.55,0.8,19.536,19.536,71.59,AHP,-2.47433,0.295029,0.00671168,1.44598 kka2_1:2_Q155Y,kka2_1:2_155,Kka2,kka2_1:2,P00552,1.44623,NO,155,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.606,-4.298,1.692,,0.525,T,A,0.64,1.49,1.592,,63.64,APA,-1.726,0.295029,0.00641853,1.44623 kka2_1:2_S11W,kka2_1:2_11,Kka2,kka2_1:2,P00552,1.44644,NO,11,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.322,-5.275,2.953,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.295029,0.00381691,1.44644 kka2_1:4_T125K,kka2_1:4_125,Kka2,kka2_1:4,P00552,1.44659,NO,125,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.622,-2.941,0.319,,0.791,T,A,0.82,0.33,1.612,,92.05,BPH,-1.56933,0.168804,0.00821755,1.44659 beta-lactamase_0_G216F,beta-lactamase_0_216,TEM-1,beta-lactamase_0,P62593,1.44794,NO,216,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.477,-4.417,2.94,,0.437,I,A,0.29,-0.58,0.834,,74.48,HOO,-1.68067,0.0500837,0.00639568,1.44794 kka2_1:2_G6A,kka2_1:2_6,Kka2,kka2_1:2,P00552,1.44807,NO,6,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.685,-2.835,1.15,,,,,,,,,71.59,AOH,-1.639,0.295029,0.00204693,1.44807 kka2_1:4_E3Y,kka2_1:4_3,Kka2,kka2_1:4,P00552,1.44914,NO,3,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.199,-2.458,0.259,,,,,,,7.22,,92.05,HAP,-2.11567,0.168804,0.00267607,1.44914 kka2_1:2_D5Q,kka2_1:2_5,Kka2,kka2_1:2,P00552,1.45045,NO,5,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.306,-3.312,2.006,,,,,,,,,71.59,PAO,-1.784,0.295029,0.00222864,1.45045 kka2_1:4_G234T,kka2_1:4_234,Kka2,kka2_1:4,P00552,1.45104,NO,234,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-2.9,-3.606,0.706,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.168804,0.00984449,1.45104 kka2_1:2_V242A,kka2_1:2_242,Kka2,kka2_1:2,P00552,1.45149,NO,242,V,A,VA,Hydrophobic,Hydrophobic,5.60847,6,0.391535,64,117,89,-28,140,88.6,-51.4,-2.687,-2.142,-0.545,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.295029,0.0102575,1.45149 beta-lactamase_0_V214C,beta-lactamase_0_214,TEM-1,beta-lactamase_0,P62593,1.45173,NO,214,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.299,-4.725,3.426,,0.375,S,A,0.44,-0.44,3.712,,74.48,BHH,-1.53733,0.0500837,0.00628442,1.45173 kka2_1:4_D5K,kka2_1:4_5,Kka2,kka2_1:4,P00552,1.45176,NO,5,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.306,-3.094,1.788,,,,,,,,,71.59,PAO,-1.784,0.168804,0.00222864,1.45176 kka2_1:4_G234M,kka2_1:4_234,Kka2,kka2_1:4,P00552,1.45193,NO,234,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-2.9,-4.839,1.939,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.168804,0.00984449,1.45193 kka2_1:4_G6W,kka2_1:4_6,Kka2,kka2_1:4,P00552,1.45265,NO,6,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.685,-5.12,3.435,,,,,,,,,71.59,AOH,-1.639,0.168804,0.00204693,1.45265 beta-lactamase_0_A222F,beta-lactamase_0_222,TEM-1,beta-lactamase_0,P62593,1.45278,NO,222,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.103,-4.23,2.127,,0.233,H,A,0.46,-0.25,2.015,,77.62,PHH,-1.63733,0.0500837,0.00466094,1.45278 kka2_1:4_I2N,kka2_1:4_2,Kka2,kka2_1:4,P00552,1.45465,NO,2,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.787,-3.72,1.933,,,,,,,,,71.59,HHA,-1.92433,0.168804,0.00246644,1.45465 kka2_1:2_Q4F,kka2_1:2_4,Kka2,kka2_1:2,P00552,1.45472,NO,4,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.361,-4.126,1.765,,,,,,,2.026,,71.59,APA,-1.95533,0.295029,0.00239179,1.45472 kka2_1:4_R239Q,kka2_1:4_239,Kka2,kka2_1:4,P00552,1.45473,NO,239,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-2.949,-4.068,1.119,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.168804,0.00835326,1.45473 kka2_1:4_G21N,kka2_1:4_21,Kka2,kka2_1:4,P00552,1.45629,NO,21,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.368,-3.58,2.212,,0.586,T,l,0.75,-0.75,3.075,,71.59,HOH,-2.10167,0.168804,0.00709648,1.45629 beta-lactamase_0_E238D,beta-lactamase_0_238,TEM-1,beta-lactamase_0,P62593,1.45689,NO,238,E,D,ED,negativeCharge,negativeCharge,3.22,5.0516,1.8316,45,147,133,-14,138.4,111.1,-27.3,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.0500837,0.00743256,1.45689 kka2_1:2_S114M,kka2_1:2_114,Kka2,kka2_1:2,P00552,1.45745,NO,114,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.527,-3.615,1.088,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.295029,0.00705262,1.45745 kka2_1:4_V16G,kka2_1:4_16,Kka2,kka2_1:4,P00552,1.45876,NO,16,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-3.087,-2.751,-0.336,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.168804,0.00694011,1.45876 kka2_1:4_V242N,kka2_1:4_242,Kka2,kka2_1:4,P00552,1.45973,NO,242,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-2.687,-3.122,0.435,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.168804,0.0102575,1.45973 kka2_1:4_A13G,kka2_1:4_13,Kka2,kka2_1:4,P00552,1.46035,NO,13,A,G,AG,Hydrophobic,Special,6,3.29388,-2.70612,60,89,75,-14,88.6,60.1,-28.5,-2.248,-2.748,0.5,,0.689,G,A,0.46,0.99,,,92.05,OHH,-1.646,0.168804,0.00784241,1.46035 kka2_1:4_Q163E,kka2_1:4_163,Kka2,kka2_1:4,P00552,1.46227,NO,163,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-2.162,-2.572,0.41,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.168804,0.00719507,1.46227 beta-lactamase_0_M127S,beta-lactamase_0_127,TEM-1,beta-lactamase_0,P62593,1.46476,NO,127,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-2.251,-3.644,1.393,,0.312,S,A,0.55,0.32,9.35,9.35,72.73,PHP,-1.40433,0.0500837,0.00437927,1.46476 kka2_1:2_V242H,kka2_1:2_242,Kka2,kka2_1:2,P00552,1.46515,NO,242,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-2.687,-3.504,0.817,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.295029,0.0102575,1.46515 kka2_1:4_A25H,kka2_1:4_25,Kka2,kka2_1:4,P00552,1.46552,NO,25,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.496,-3.145,0.649,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.168804,0.00595636,1.46552 kka2_1:2_R253K,kka2_1:2_253,Kka2,kka2_1:2,P00552,1.46707,NO,253,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.356,-1.563,0.207,,0.226,H,A,1.2,0.05,0.295,,52.27,PBH,-1.973,0.295029,0.0144195,1.46707 kka2_1:2_Q4L,kka2_1:2_4,Kka2,kka2_1:2,P00552,1.47048,NO,4,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.361,-3.406,1.045,,,,,,,2.026,,71.59,APA,-1.95533,0.295029,0.00239179,1.47048 kka2_1:2_S251H,kka2_1:2_251,Kka2,kka2_1:2,P00552,1.47055,NO,251,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.636,-3.222,0.586,,0.712,H,A,0.27,-0.25,32.832,32.832,71.59,APP,-2.09367,0.295029,0.0138916,1.47055 kka2_1:4_A176Y,kka2_1:4_176,Kka2,kka2_1:4,P00552,1.47082,NO,176,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.621,-4.408,2.787,,0.806,H,A,0.46,-0.03,0.357,,65.53,BHB,-2.26667,0.168804,0.0083587,1.47082 kka2_1:4_D238Q,kka2_1:4_238,Kka2,kka2_1:4,P00552,1.47127,NO,238,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.83,-2.348,-0.482,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.168804,0.0113863,1.47127 beta-lactamase_0_T179N,beta-lactamase_0_179,TEM-1,beta-lactamase_0,P62593,1.47239,NO,179,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.085,-3.487,2.402,,,E,B,0.22,-1.38,0.367,,73.08,PPH,-1.557,0.0500837,0.00226045,1.47239 kka2_1:2_A13D,kka2_1:2_13,Kka2,kka2_1:2,P00552,1.47311,NO,13,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.248,-2.729,0.481,,0.689,G,A,0.46,0.99,,,92.05,OHH,-1.646,0.295029,0.00784241,1.47311 kka2_1:4_Q4M,kka2_1:4_4,Kka2,kka2_1:4,P00552,1.47354,NO,4,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.361,-4.464,2.103,,,,,,,2.026,,71.59,APA,-1.95533,0.168804,0.00239179,1.47354 kka2_1:4_Q4L,kka2_1:4_4,Kka2,kka2_1:4,P00552,1.47568,NO,4,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-2.361,-3.406,1.045,,,,,,,2.026,,71.59,APA,-1.95533,0.168804,0.00239179,1.47568 kka2_1:4_E160F,kka2_1:4_160,Kka2,kka2_1:4,P00552,1.47676,NO,160,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.683,-4.47,2.787,,0.989,G,A,1.04,2.28,2.531,,71.59,AAA,-1.36133,0.168804,0.00935762,1.47676 kka2_1:4_G234W,kka2_1:4_234,Kka2,kka2_1:4,P00552,1.47684,NO,234,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-2.9,-5.618,2.718,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.168804,0.00984449,1.47684 beta-lactamase_0_V214G,beta-lactamase_0_214,TEM-1,beta-lactamase_0,P62593,1.47827,NO,214,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.299,-3.571,2.272,,0.375,S,A,0.44,-0.44,3.712,,74.48,BHH,-1.53733,0.0500837,0.00628442,1.47827 kka2_1:4_L232F,kka2_1:4_232,Kka2,kka2_1:4,P00552,1.47866,NO,232,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.514,-2.061,0.547,,0.307,H,A,0.55,-0.49,5.504,,53.03,AHO,-1.42133,0.168804,0.00800103,1.47866 beta-lactamase_0_A148M,beta-lactamase_0_148,TEM-1,beta-lactamase_0,P62593,1.47941,NO,148,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.757,-4.798,3.041,,0.379,H,A,0.46,-0.55,19.42,19.42,72.73,PHH,-1.40167,0.0500837,0.00547053,1.47941 kka2_1:4_S251P,kka2_1:4_251,Kka2,kka2_1:4,P00552,1.4796,NO,251,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.636,-2.034,-0.602,,0.712,H,A,0.77,-0.25,,,71.59,APP,-2.09367,0.168804,0.0138916,1.4796 kka2_1:4_G234Q,kka2_1:4_234,Kka2,kka2_1:4,P00552,1.47964,NO,234,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-2.9,-2.619,-0.281,,0.494,H,A,0.29,-0.29,,,71.59,OOA,-1.86767,0.168804,0.00984449,1.47964 kka2_1:4_T225C,kka2_1:4_225,Kka2,kka2_1:4,P00552,1.48244,NO,225,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.393,-1.895,-0.498,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.168804,0.0113598,1.48244 beta-lactamase_0_D212M,beta-lactamase_0_212,TEM-1,beta-lactamase_0,P62593,1.48271,NO,212,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.624,-4.83,3.206,,0.037,,b,0.75,-0.58,3.34,,74.48,HAB,-1.77667,0.0500837,0.00644302,1.48271 beta-lactamase_0_P25Q,beta-lactamase_0_25,TEM-1,beta-lactamase_0,P62593,1.48534,NO,25,P,Q,PQ,Special,Polar,6.3,6.24429,-0.0557143,76,115,146,31,112.7,143.8,31.1,-1.526,-2.522,0.996,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.0500837,0.00347571,1.48534 kka2_1:4_A168L,kka2_1:4_168,Kka2,kka2_1:4,P00552,1.48692,NO,168,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.989,-3.651,1.662,,0.67,H,A,0.46,0.15,,,64.39,OHA,-2.12933,0.168804,0.00806773,1.48692 kka2_1:2_G10P,kka2_1:2_10,Kka2,kka2_1:2,P00552,1.48723,NO,10,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.921,-2.317,0.396,,,,,,,2.192,,71.59,HOP,-2.10733,0.295029,0.00289233,1.48723 kka2_1:4_A248M,kka2_1:4_248,Kka2,kka2_1:4,P00552,1.49007,NO,248,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.124,-4.765,2.641,,0.825,S,b,0.46,0.46,,,92.05,HHO,-2.15,0.168804,0.0125484,1.49007 beta-lactamase_0_A268T,beta-lactamase_0_268,TEM-1,beta-lactamase_0,P62593,1.4935,NO,268,A,T,AT,Hydrophobic,Polar,6,5.6,-0.4,58,89,119,30,88.6,116.1,27.5,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.0500837,0.0102525,1.4935 kka2_1:4_Q4V,kka2_1:4_4,Kka2,kka2_1:4,P00552,1.49467,NO,4,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.361,-3.536,1.175,,,,,,,2.026,,71.59,APA,-1.95533,0.168804,0.00239179,1.49467 kka2_1:4_E3R,kka2_1:4_3,Kka2,kka2_1:4,P00552,1.49543,NO,3,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-2.199,-3.722,1.523,,,,,,,7.22,,92.05,HAP,-2.11567,0.168804,0.00267607,1.49543 beta-lactamase_0_A211M,beta-lactamase_0_211,TEM-1,beta-lactamase_0,P62593,1.49662,NO,211,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.896,-3.437,1.541,,0.369,T,A,0.46,-0.69,8.527,8.527,77.62,AHA,-1.94633,0.0500837,0.00648183,1.49662 beta-lactamase_0_E272T,beta-lactamase_0_272,TEM-1,beta-lactamase_0,P62593,1.49692,NO,272,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.0500837,0.00545371,1.49692 beta-lactamase_0_Q203H,beta-lactamase_0_203,TEM-1,beta-lactamase_0,P62593,1.50539,NO,203,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-2.168,-4.663,2.495,,0.47,H,A,0.64,-0.38,14.541,14.541,65.38,BPP,-1.614,0.0500837,0.00631514,1.50539 beta-lactamase_0_V214R,beta-lactamase_0_214,TEM-1,beta-lactamase_0,P62593,1.50753,NO,214,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.299,-4.047,2.748,,0.375,S,A,0.44,-0.44,3.712,,74.48,BHH,-1.53733,0.0500837,0.00628442,1.50753 kka2_1:4_Q252T,kka2_1:4_252,Kka2,kka2_1:4,P00552,1.51098,NO,252,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.63,-2.832,0.202,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.168804,0.0121001,1.51098 beta-lactamase_0_R159F,beta-lactamase_0_159,TEM-1,beta-lactamase_0,P62593,1.51449,NO,159,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-0.94,-4.255,3.315,,0.316,,B,1.2,-0.55,1.426,,64.34,PBH,-1.011,0.0500837,0.00108472,1.51449 beta-lactamase_0_D212W,beta-lactamase_0_212,TEM-1,beta-lactamase_0,P62593,1.5154,NO,212,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.624,-5.54,3.916,,0.037,,b,0.75,-0.58,3.34,,74.48,HAB,-1.77667,0.0500837,0.00644302,1.5154 kka2_1:2_V242R,kka2_1:2_242,Kka2,kka2_1:2,P00552,1.5155,NO,242,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-2.687,-2.299,-0.388,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.295029,0.0102575,1.5155 beta-lactamase_0_T187N,beta-lactamase_0_187,TEM-1,beta-lactamase_0,P62593,1.51637,NO,187,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.401,-2.373,0.972,,0.007,H,A,0.22,-1.19,3.259,,67.48,PPH,-1.69633,0.0500837,0.00491782,1.51637 kka2_1:2_D180I,kka2_1:2_180,Kka2,kka2_1:2,P00552,1.51679,NO,180,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.416,-3.372,0.956,,1.03,S,a,0.75,1.5,1.27,,71.59,OAO,-2.02933,0.295029,0.00756412,1.51679 kka2_1:4_L7A,kka2_1:4_7,Kka2,kka2_1:4,P00552,1.52045,NO,7,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.926,-3.033,1.107,,,,,,,3.012,,71.59,OHB,-2.12333,0.168804,0.00269456,1.52045 beta-lactamase_0_H110S,beta-lactamase_0_110,TEM-1,beta-lactamase_0,P62593,1.52645,NO,110,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-1.706,-3.537,1.831,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.0500837,0.00441499,1.52645 beta-lactamase_0_E272G,beta-lactamase_0_272,TEM-1,beta-lactamase_0,P62593,1.52985,NO,272,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.0500837,0.00545371,1.52985 beta-lactamase_0_S201H,beta-lactamase_0_201,TEM-1,beta-lactamase_0,P62593,1.53122,NO,201,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.183,-4.595,3.412,,0.064,H,A,0.27,-0.07,3.54,,64.69,HPB,-1.451,0.0500837,0.00198815,1.53122 beta-lactamase_0_V214F,beta-lactamase_0_214,TEM-1,beta-lactamase_0,P62593,1.53847,NO,214,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.299,-3.997,2.698,,0.375,S,A,0.44,-0.44,3.712,,74.48,BHH,-1.53733,0.0500837,0.00628442,1.53847 beta-lactamase_0_E238F,beta-lactamase_0_238,TEM-1,beta-lactamase_0,P62593,1.5406,NO,238,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.002,,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.0500837,0.00743256,1.5406 beta-lactamase_0_P224W,beta-lactamase_0_224,TEM-1,beta-lactamase_0,P62593,1.54623,NO,224,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-0.893,-5.546,4.653,,0.383,,B,0.52,-0.3,3.587,,74.48,HOH,-1.26433,0.0500837,0.00189564,1.54623 beta-lactamase_0_E272H,beta-lactamase_0_272,TEM-1,beta-lactamase_0,P62593,1.54833,NO,272,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.0500837,0.00545371,1.54833 kka2_1:4_V46N,kka2_1:4_46,Kka2,kka2_1:4,P00552,1.55243,NO,46,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-2.62,-3.225,0.605,,0.192,.,B,0.44,-1.12,9.564,,92.05,OHH,-1.88633,0.168804,0.00631301,1.55243 beta-lactamase_0_H110K,beta-lactamase_0_110,TEM-1,beta-lactamase_0,P62593,1.55479,NO,110,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-1.706,-2.755,1.049,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.0500837,0.00441499,1.55479 beta-lactamase_0_S104D,beta-lactamase_0_104,TEM-1,beta-lactamase_0,P62593,1.55856,NO,104,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.015,-3.41,2.395,,0.04,,b,0.27,0.57,1.148,,63.29,HPO,-1.05267,0.0500837,0.00218083,1.55856 beta-lactamase_0_V214Y,beta-lactamase_0_214,TEM-1,beta-lactamase_0,P62593,1.56687,NO,214,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.299,-4.125,2.826,,0.375,S,A,0.44,-0.44,3.712,,74.48,BHH,-1.53733,0.0500837,0.00628442,1.56687 beta-lactamase_0_A222Y,beta-lactamase_0_222,TEM-1,beta-lactamase_0,P62593,1.57036,NO,222,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.103,-4.186,2.083,,0.233,H,A,0.46,-0.25,2.015,,77.62,PHH,-1.63733,0.0500837,0.00466094,1.57036 beta-lactamase_0_A268I,beta-lactamase_0_268,TEM-1,beta-lactamase_0,P62593,1.57195,NO,268,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.0500837,0.0102525,1.57195 beta-lactamase_0_D212R,beta-lactamase_0_212,TEM-1,beta-lactamase_0,P62593,1.57246,NO,212,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.624,-3.921,2.297,,0.037,,b,0.75,-0.58,3.34,,74.48,HAB,-1.77667,0.0500837,0.00644302,1.57246 beta-lactamase_0_V214H,beta-lactamase_0_214,TEM-1,beta-lactamase_0,P62593,1.57763,NO,214,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.299,-4.922,3.623,,0.375,S,A,0.44,-0.44,3.712,,74.48,BHH,-1.53733,0.0500837,0.00628442,1.57763 beta-lactamase_0_A211C,beta-lactamase_0_211,TEM-1,beta-lactamase_0,P62593,1.58235,NO,211,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.896,-5.066,3.17,,0.369,T,A,0.46,-0.69,8.527,8.527,77.62,AHA,-1.94633,0.0500837,0.00648183,1.58235 beta-lactamase_0_S122T,beta-lactamase_0_122,TEM-1,beta-lactamase_0,P62593,1.60783,NO,122,S,T,ST,Polar,Polar,5.68,5.6,-0.08,58,105,119,14,89,116.1,27.1,-2.406,-2.952,0.546,,0.352,H,A,0.27,-0.54,30.794,30.794,77.62,OPH,-1.39767,0.0500837,0.00497825,1.60783 beta-lactamase_0_M180L,beta-lactamase_0_180,TEM-1,beta-lactamase_0,P62593,1.6101,NO,180,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-2.795,-3.19,0.395,,0.242,,B,0.55,-0.94,2.892,,77.62,PHO,-1.56433,0.0500837,0.00552048,1.6101 beta-lactamase_0_D271I,beta-lactamase_0_271,TEM-1,beta-lactamase_0,P62593,1.61141,NO,271,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.249,,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.0500837,0.00752082,1.61141 beta-lactamase_0_V29M,beta-lactamase_0_29,TEM-1,beta-lactamase_0,P62593,1.62655,NO,29,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-2.856,-4.721,1.865,,0.733,H,A,0.44,-0.78,21.916,21.916,93.01,HHB,-2.24733,0.0500837,0.00318969,1.62655 beta-lactamase_0_R118C,beta-lactamase_0_118,TEM-1,beta-lactamase_0,P62593,1.64279,NO,118,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.413,-4.992,2.579,,0.457,H,A,1.2,1.39,3.961,,77.62,HBA,-1.785,0.0500837,0.00538794,1.64279 beta-lactamase_0_M209L,beta-lactamase_0_209,TEM-1,beta-lactamase_0,P62593,1.64601,NO,209,M,L,ML,Hydrophobic,Hydrophobic,5.74,9.7088,3.9688,15,149,131,-18,162.9,166.7,3.8,-1.442,-1.689,0.247,,,H,A,0.55,-0.97,3.876,,64.69,HHA,-1.52633,0.0500837,0.00625021,1.64601 beta-lactamase_0_L219I,beta-lactamase_0_219,TEM-1,beta-lactamase_0,P62593,1.65478,NO,219,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.313,-1.692,0.379,,,I,A,0.55,-0.51,6.513,6.513,74.48,HHB,-1.21533,0.0500837,0.00664345,1.65478 beta-lactamase_0_T138K,beta-lactamase_0_138,TEM-1,beta-lactamase_0,P62593,1.66382,NO,138,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.506,-2.186,-0.32,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.0500837,0.00487868,1.66382 beta-lactamase_0_M127N,beta-lactamase_0_127,TEM-1,beta-lactamase_0,P62593,1.67169,NO,127,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-2.251,-4.047,1.796,,0.312,S,A,0.55,0.32,9.35,9.35,72.73,PHP,-1.40433,0.0500837,0.00437927,1.67169 beta-lactamase_0_V214I,beta-lactamase_0_214,TEM-1,beta-lactamase_0,P62593,1.67665,NO,214,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-1.299,-3.053,1.754,,0.375,S,A,0.44,-0.44,3.712,,74.48,BHH,-1.53733,0.0500837,0.00628442,1.67665 beta-lactamase_0_V214D,beta-lactamase_0_214,TEM-1,beta-lactamase_0,P62593,1.69158,NO,214,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.299,-3.873,2.574,,0.375,S,A,0.44,-0.44,3.712,,74.48,BHH,-1.53733,0.0500837,0.00628442,1.69158 beta-lactamase_0_I258C,beta-lactamase_0_258,TEM-1,beta-lactamase_0,P62593,1.69643,NO,258,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.975,,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.0500837,0.007931,1.69643 beta-lactamase_0_A268D,beta-lactamase_0_268,TEM-1,beta-lactamase_0,P62593,1.69927,NO,268,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.0500837,0.0102525,1.69927 beta-lactamase_0_M180R,beta-lactamase_0_180,TEM-1,beta-lactamase_0,P62593,1.72431,NO,180,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-2.795,-3.843,1.048,,0.242,,B,0.55,-0.94,2.892,,77.62,PHO,-1.56433,0.0500837,0.00552048,1.72431 beta-lactamase_0_V214P,beta-lactamase_0_214,TEM-1,beta-lactamase_0,P62593,1.7425,NO,214,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.299,-3.919,2.62,,0.375,S,A,0.44,-0.44,3.712,,74.48,BHH,-1.53733,0.0500837,0.00628442,1.7425 beta-lactamase_0_S122M,beta-lactamase_0_122,TEM-1,beta-lactamase_0,P62593,1.74447,NO,122,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.406,-4.704,2.298,,0.352,H,A,0.27,-0.54,30.794,30.794,77.62,OPH,-1.39767,0.0500837,0.00497825,1.74447 beta-lactamase_0_C121D,beta-lactamase_0_121,TEM-1,beta-lactamase_0,P62593,1.75536,NO,121,C,D,CD,Special,negativeCharge,5.07,5.0516,-0.0184,154,121,133,12,108.5,111.1,2.6,-0.953,-3.916,2.963,,,H,A,0.46,-0.81,3.302,,63.29,HOP,-1.46767,0.0500837,0.000744322,1.75536 beta-lactamase_0_A132Q,beta-lactamase_0_132,TEM-1,beta-lactamase_0,P62593,1.78519,NO,132,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.9,-3.943,3.043,,,H,A,0.46,-0.93,2.249,,64.69,PHH,-1.138,0.0500837,0.000962524,1.78519 beta-lactamase_0_S122F,beta-lactamase_0_122,TEM-1,beta-lactamase_0,P62593,1.78645,NO,122,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.406,-3.279,0.873,,0.352,H,A,0.27,-0.54,30.794,30.794,77.62,OPH,-1.39767,0.0500837,0.00497825,1.78645 beta-lactamase_0_A268Q,beta-lactamase_0_268,TEM-1,beta-lactamase_0,P62593,1.80352,NO,268,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.0500837,0.0102525,1.80352 beta-lactamase_0_A222K,beta-lactamase_0_222,TEM-1,beta-lactamase_0,P62593,1.82673,NO,222,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.103,-3.694,1.591,,0.233,H,A,0.46,-0.25,2.015,,77.62,PHH,-1.63733,0.0500837,0.00466094,1.82673 beta-lactamase_0_D212T,beta-lactamase_0_212,TEM-1,beta-lactamase_0,P62593,1.83167,NO,212,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.624,-2.54,0.916,,0.037,,b,0.75,-0.58,3.34,,74.48,HAB,-1.77667,0.0500837,0.00644302,1.83167 beta-lactamase_0_S122A,beta-lactamase_0_122,TEM-1,beta-lactamase_0,P62593,1.8503,NO,122,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.406,-2.18,-0.226,,0.352,H,A,0.27,-0.54,30.794,30.794,77.62,OPH,-1.39767,0.0500837,0.00497825,1.8503 beta-lactamase_0_C121H,beta-lactamase_0_121,TEM-1,beta-lactamase_0,P62593,1.86427,NO,121,C,H,CH,Special,PositiveCharge,5.07,7.59,2.52,174,121,155,34,108.5,153.2,44.7,-0.953,-4.827,3.874,,,H,A,0.46,-0.81,3.302,,63.29,HOP,-1.46767,0.0500837,0.000744322,1.86427 beta-lactamase_0_S122Q,beta-lactamase_0_122,TEM-1,beta-lactamase_0,P62593,1.8775,NO,122,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.406,-2.914,0.508,,0.352,H,A,0.27,-0.54,30.794,30.794,77.62,OPH,-1.39767,0.0500837,0.00497825,1.8775 beta-lactamase_0_M127V,beta-lactamase_0_127,TEM-1,beta-lactamase_0,P62593,1.87968,NO,127,M,V,MV,Hydrophobic,Hydrophobic,5.74,5.60847,-0.131535,21,149,117,-32,162.9,140,-22.9,-2.251,-2.333,0.082,,0.312,S,A,0.55,0.32,9.35,9.35,72.73,PHP,-1.40433,0.0500837,0.00437927,1.87968 beta-lactamase_0_E210P,beta-lactamase_0_210,TEM-1,beta-lactamase_0,P62593,1.87999,NO,210,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.319,-4.023,1.704,,0.476,H,A,1.04,0.75,3.618,,77.62,HAH,-1.88567,0.0500837,0.00663582,1.87999 beta-lactamase_0_A268V,beta-lactamase_0_268,TEM-1,beta-lactamase_0,P62593,1.89456,NO,268,A,V,AV,Hydrophobic,Hydrophobic,6,5.60847,-0.391535,64,89,117,28,88.6,140,51.4,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.0500837,0.0102525,1.89456 beta-lactamase_0_D99C,beta-lactamase_0_99,TEM-1,beta-lactamase_0,P62593,1.90537,NO,99,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.191,-5.117,3.926,,0.402,G,A,0.75,0.36,0.374,,64.69,PAH,-1.794,0.0500837,0.00305446,1.90537 beta-lactamase_0_C121I,beta-lactamase_0_121,TEM-1,beta-lactamase_0,P62593,1.91244,NO,121,C,I,CI,Special,Hydrophobic,5.07,6.02,0.95,198,121,131,10,108.5,166.7,58.2,-0.953,-3.628,2.675,,,H,A,0.46,-0.81,3.302,,63.29,HOP,-1.46767,0.0500837,0.000744322,1.91244 beta-lactamase_0_S122G,beta-lactamase_0_122,TEM-1,beta-lactamase_0,P62593,1.94128,NO,122,S,G,SG,Polar,Special,5.68,3.29388,-2.38612,56,105,75,-30,89,60.1,-28.9,-2.406,-3.475,1.069,,0.352,H,A,0.27,-0.54,30.794,30.794,77.62,OPH,-1.39767,0.0500837,0.00497825,1.94128 beta-lactamase_0_M180P,beta-lactamase_0_180,TEM-1,beta-lactamase_0,P62593,1.94968,NO,180,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-2.795,-2.76,-0.035,,0.242,,B,0.55,-0.94,2.892,,77.62,PHO,-1.56433,0.0500837,0.00552048,1.94968 beta-lactamase_0_A268P,beta-lactamase_0_268,TEM-1,beta-lactamase_0,P62593,1.95074,NO,268,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.0500837,0.0102525,1.95074 beta-lactamase_0_M180H,beta-lactamase_0_180,TEM-1,beta-lactamase_0,P62593,2.01793,NO,180,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-2.795,-4.627,1.832,,0.242,,B,0.55,-0.94,2.892,,77.62,PHO,-1.56433,0.0500837,0.00552048,2.01793 beta-lactamase_0_S122C,beta-lactamase_0_122,TEM-1,beta-lactamase_0,P62593,2.03919,NO,122,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-2.406,-5.091,2.685,,0.352,H,A,0.27,-0.54,30.794,30.794,77.62,OPH,-1.39767,0.0500837,0.00497825,2.03919 beta-lactamase_0_A268F,beta-lactamase_0_268,TEM-1,beta-lactamase_0,P62593,2.04545,NO,268,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.0500837,0.0102525,2.04545 beta-lactamase_0_S256C,beta-lactamase_0_256,TEM-1,beta-lactamase_0,P62593,2.09177,NO,256,S,C,SC,Polar,Special,5.68,5.07,-0.61,112,105,121,16,89,108.5,19.5,-1.621,,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.0500837,0.00710634,2.09177 beta-lactamase_0_M127G,beta-lactamase_0_127,TEM-1,beta-lactamase_0,P62593,2.11064,NO,127,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-2.251,-3.785,1.534,,0.312,S,A,0.55,0.32,9.35,9.35,72.73,PHP,-1.40433,0.0500837,0.00437927,2.11064 beta-lactamase_0_A268R,beta-lactamase_0_268,TEM-1,beta-lactamase_0,P62593,2.11993,NO,268,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.0500837,0.0102525,2.11993 beta-lactamase_0_S122N,beta-lactamase_0_122,TEM-1,beta-lactamase_0,P62593,2.12694,NO,122,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-2.406,-3.042,0.636,,0.352,H,A,0.27,-0.54,30.794,30.794,77.62,OPH,-1.39767,0.0500837,0.00497825,2.12694 beta-lactamase_0_M127T,beta-lactamase_0_127,TEM-1,beta-lactamase_0,P62593,2.14284,NO,127,M,T,MT,Hydrophobic,Polar,5.74,5.6,-0.14,81,149,119,-30,162.9,116.1,-46.8,-2.251,-2.593,0.342,,0.312,S,A,0.55,0.32,9.35,9.35,72.73,PHP,-1.40433,0.0500837,0.00437927,2.14284 beta-lactamase_0_E272Q,beta-lactamase_0_272,TEM-1,beta-lactamase_0,P62593,2.15275,NO,272,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-1.127,,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.0500837,0.00545371,2.15275 beta-lactamase_0_S122L,beta-lactamase_0_122,TEM-1,beta-lactamase_0,P62593,2.1671,NO,122,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.406,-2.918,0.512,,0.352,H,A,0.27,-0.54,30.794,30.794,77.62,OPH,-1.39767,0.0500837,0.00497825,2.1671 beta-lactamase_0_A268S,beta-lactamase_0_268,TEM-1,beta-lactamase_0,P62593,2.20512,NO,268,A,S,AS,Hydrophobic,Polar,6,5.68,-0.32,99,89,105,16,88.6,89,0.4,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.0500837,0.0102525,2.20512 beta-lactamase_0_A268M,beta-lactamase_0_268,TEM-1,beta-lactamase_0,P62593,2.21691,NO,268,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.023,-2.456,0.433,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.0500837,0.0102525,2.21691 beta-lactamase_0_M209Q,beta-lactamase_0_209,TEM-1,beta-lactamase_0,P62593,2.24144,NO,209,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.442,-3.974,2.532,,,H,A,0.55,-0.97,3.876,,64.69,HHA,-1.52633,0.0500837,0.00625021,2.24144 beta-lactamase_0_S122W,beta-lactamase_0_122,TEM-1,beta-lactamase_0,P62593,2.29275,NO,122,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.406,-5.469,3.063,,0.352,H,A,0.27,-0.54,30.794,30.794,77.62,OPH,-1.39767,0.0500837,0.00497825,2.29275 beta-lactamase_0_A268L,beta-lactamase_0_268,TEM-1,beta-lactamase_0,P62593,2.31897,NO,268,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.0500837,0.0102525,2.31897 beta-lactamase_0_A268W,beta-lactamase_0_268,TEM-1,beta-lactamase_0,P62593,2.32826,NO,268,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.0500837,0.0102525,2.32826 beta-lactamase_0_A268N,beta-lactamase_0_268,TEM-1,beta-lactamase_0,P62593,2.32841,NO,268,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.0500837,0.0102525,2.32841 beta-lactamase_0_S122I,beta-lactamase_0_122,TEM-1,beta-lactamase_0,P62593,2.34806,NO,122,S,I,SI,Polar,Hydrophobic,5.68,6.02,0.34,142,105,131,26,89,166.7,77.7,-2.406,-3.138,0.732,,0.352,H,A,0.27,-0.54,30.794,30.794,77.62,OPH,-1.39767,0.0500837,0.00497825,2.34806 beta-lactamase_0_A268H,beta-lactamase_0_268,TEM-1,beta-lactamase_0,P62593,2.39121,NO,268,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.0500837,0.0102525,2.39121 beta-lactamase_0_A268Y,beta-lactamase_0_268,TEM-1,beta-lactamase_0,P62593,2.40814,NO,268,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.0500837,0.0102525,2.40814 beta-lactamase_0_E210A,beta-lactamase_0_210,TEM-1,beta-lactamase_0,P62593,2.42507,NO,210,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-2.319,-3.162,0.843,,0.476,H,A,1.04,0.75,3.618,,77.62,HAH,-1.88567,0.0500837,0.00663582,2.42507 beta-lactamase_0_D212Q,beta-lactamase_0_212,TEM-1,beta-lactamase_0,P62593,2.49653,NO,212,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-1.624,-3.949,2.325,,0.037,,b,0.75,-0.58,3.34,,74.48,HAB,-1.77667,0.0500837,0.00644302,2.49653 beta-lactamase_0_S122V,beta-lactamase_0_122,TEM-1,beta-lactamase_0,P62593,2.50069,NO,122,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.406,-2.967,0.561,,0.352,H,A,0.27,-0.54,30.794,30.794,77.62,OPH,-1.39767,0.0500837,0.00497825,2.50069 beta-lactamase_0_E195I,beta-lactamase_0_195,TEM-1,beta-lactamase_0,P62593,2.53166,NO,195,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.186,-4.191,2.005,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.0500837,0.00496565,2.53166 beta-lactamase_0_S122K,beta-lactamase_0_122,TEM-1,beta-lactamase_0,P62593,2.61212,NO,122,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.406,-3.55,1.144,,0.352,H,A,0.27,-0.54,30.794,30.794,77.62,OPH,-1.39767,0.0500837,0.00497825,2.61212 beta-lactamase_0_A268C,beta-lactamase_0_268,TEM-1,beta-lactamase_0,P62593,2.82513,NO,268,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.023,,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.0500837,0.0102525,2.82513 beta-lactamase_0_M127A,beta-lactamase_0_127,TEM-1,beta-lactamase_0,P62593,3.59257,NO,127,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-2.251,-3.303,1.052,,0.312,S,A,0.55,0.32,9.35,9.35,72.73,PHP,-1.40433,0.0500837,0.00437927,3.59257 beta-lactamase_0_M180Q,beta-lactamase_0_180,TEM-1,beta-lactamase_0,P62593,3.89961,NO,180,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-2.795,-3.924,1.129,,0.242,,B,0.55,-0.94,2.892,,77.62,PHO,-1.56433,0.0500837,0.00552048,3.89961 beta-lactamase_0_M127D,beta-lactamase_0_127,TEM-1,beta-lactamase_0,P62593,4.84394,NO,127,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-2.251,-3.966,1.715,,0.312,S,A,0.55,0.32,9.35,9.35,72.73,PHP,-1.40433,0.0500837,0.00437927,4.84394 beta-lactamase_0_A123A,beta-lactamase_0_123,TEM-1,beta-lactamase_0,P62593,,YES,123,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.834,-0.834,,,0.039,H,A,0.46,-0.72,1.308,,41.26,PHH,-1.47367,0.0500837,0.0010157,0.398075 beta-lactamase_0_A124A,beta-lactamase_0_124,TEM-1,beta-lactamase_0,P62593,,YES,124,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.181,-1.181,,,,H,A,0.46,-0.9,1.876,,64.34,HHH,-1.152,0.0500837,0.00481399,0.93974 beta-lactamase_0_A132A,beta-lactamase_0_132,TEM-1,beta-lactamase_0,P62593,,YES,132,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.9,-0.9,,,,H,A,0.46,-0.93,2.249,,64.69,PHH,-1.138,0.0500837,0.000962524,0.950825 beta-lactamase_0_A133A,beta-lactamase_0_133,TEM-1,beta-lactamase_0,P62593,,YES,133,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.186,-1.186,,,,H,A,0.46,-0.86,2.148,,67.83,HHP,-0.988333,0.0500837,0.00468022,0.903366 beta-lactamase_0_A148A,beta-lactamase_0_148,TEM-1,beta-lactamase_0,P62593,,YES,148,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.757,-1.757,,,0.379,H,A,0.46,-0.55,19.42,19.42,72.73,PHH,-1.40167,0.0500837,0.00547053,0.995345 beta-lactamase_0_A170A,beta-lactamase_0_170,TEM-1,beta-lactamase_0,P62593,,YES,170,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.237,-1.237,,,0.126,,L,0.46,-0.35,2.427,,64.69,AHH,-1.63267,0.0500837,0.00431903,0.854233 beta-lactamase_0_A182A,beta-lactamase_0_182,TEM-1,beta-lactamase_0,P62593,,YES,182,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.777,-1.777,,,0.136,H,A,0.46,-0.66,10.765,10.765,93.01,OHH,-1.27367,0.0500837,0.00559099,0.979956 beta-lactamase_0_A183A,beta-lactamase_0_183,TEM-1,beta-lactamase_0,P62593,,YES,183,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.231,-1.231,,,0.155,H,A,0.46,-0.91,1.48,,77.62,HHH,-1.53367,0.0500837,0.00296631,0.876579 beta-lactamase_0_A185A,beta-lactamase_0_185,TEM-1,beta-lactamase_0,P62593,,YES,185,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.406,-1.406,,,,H,A,0.46,-1.02,1.203,,65.03,HHP,-1.84033,0.0500837,0.00467449,0.901632 beta-lactamase_0_A200A,beta-lactamase_0_200,TEM-1,beta-lactamase_0,P62593,,YES,200,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.878,-1.878,,,0.757,H,A,0.46,-0.19,16.368,16.368,77.62,HHP,-2.001,0.0500837,0.0060056,0.916137 beta-lactamase_0_A211A,beta-lactamase_0_211,TEM-1,beta-lactamase_0,P62593,,YES,211,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.896,-1.896,,,0.369,T,A,0.46,-0.69,8.527,8.527,77.62,AHA,-1.94633,0.0500837,0.00648183,1.0172 beta-lactamase_0_A215A,beta-lactamase_0_215,TEM-1,beta-lactamase_0,P62593,,YES,215,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.503,-1.503,,,,,a,0.46,-0.93,0.494,,74.48,HHO,-1.42633,0.0500837,0.00544007,0.921297 beta-lactamase_0_A222A,beta-lactamase_0_222,TEM-1,beta-lactamase_0,P62593,,YES,222,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.103,-2.103,,,0.233,H,A,0.46,-0.25,2.015,,77.62,PHH,-1.63733,0.0500837,0.00466094,0.969906 beta-lactamase_0_A225A,beta-lactamase_0_225,TEM-1,beta-lactamase_0,P62593,,YES,225,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.845,-1.845,,,1,T,B,0.46,-0.38,11.722,11.722,74.48,OHO,-1.39967,0.0500837,0.00465057,0.884476 beta-lactamase_0_A230A,beta-lactamase_0_230,TEM-1,beta-lactamase_0,P62593,,YES,230,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.154,-1.154,,,0.01,E,B,0.46,-1.17,2.179,,50,HHA,-1.079,0.0500837,0.00516841,0.942861 beta-lactamase_0_A235A,beta-lactamase_0_235,TEM-1,beta-lactamase_0,P62593,,YES,235,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.266,-1.266,,,0.32,E,B,0.46,-0.86,2.261,,50,OHO,-0.89,0.0500837,0.00493474,0.870743 beta-lactamase_0_A246A,beta-lactamase_0_246,TEM-1,beta-lactamase_0,P62593,,YES,246,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.121,-2.121,,,0.01,E,B,0.46,-1.01,1.201,,73.78,HHH,-1.55633,0.0500837,0.00569458,0.932509 beta-lactamase_0_A247A,beta-lactamase_0_247,TEM-1,beta-lactamase_0,P62593,,YES,247,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.48,-1.48,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.0500837,0.00611275,0.925109 beta-lactamase_0_A268A,beta-lactamase_0_268,TEM-1,beta-lactamase_0,P62593,,YES,268,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.023,-2.023,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.0500837,0.0102525,1.06512 beta-lactamase_0_A278A,beta-lactamase_0_278,TEM-1,beta-lactamase_0,P62593,,YES,278,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.348,-1.348,,,0.015,H,A,0.48,-0.85,4.624,,63.29,HHA,-1.41833,0.0500837,0.0310297,0.936623 beta-lactamase_0_A282A,beta-lactamase_0_282,TEM-1,beta-lactamase_0,P62593,,YES,282,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.586,-1.586,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.0500837,0.0449821,0.812823 beta-lactamase_0_A34A,beta-lactamase_0_34,TEM-1,beta-lactamase_0,P62593,,YES,34,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.059,-2.059,,,,H,A,0.46,-0.54,3.998,,73.78,AHA,-1.74967,0.0500837,0.00407913,0.912915 beta-lactamase_0_A40A,beta-lactamase_0_40,TEM-1,beta-lactamase_0,P62593,,YES,40,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.402,-1.402,,,0.155,S,B,0.46,0.21,0.783,,73.78,OHB,-1.40267,0.0500837,0.00490026,0.825703 beta-lactamase_0_A77A,beta-lactamase_0_77,TEM-1,beta-lactamase_0,P62593,,YES,77,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.234,-1.234,,,0.039,H,A,0.46,-0.56,2.591,,64.34,OHH,-1.294,0.0500837,0.00282362,0.973684 beta-lactamase_0_A84A,beta-lactamase_0_84,TEM-1,beta-lactamase_0,P62593,,YES,84,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.651,-1.651,,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.0500837,0.00503822,0.987313 beta-lactamase_0_C121C,beta-lactamase_0_121,TEM-1,beta-lactamase_0,P62593,,YES,121,C,C,CC,Special,Special,5.07,5.07,0,0,121,121,0,108.5,108.5,0,-0.953,-0.953,,,,H,A,0.46,-0.81,3.302,,63.29,HOP,-1.46767,0.0500837,0.000744322,0.812973 beta-lactamase_0_C75C,beta-lactamase_0_75,TEM-1,beta-lactamase_0,P62593,,YES,75,C,C,CC,Special,Special,5.07,5.07,0,0,121,121,0,108.5,108.5,0,-1.245,-1.245,,,,H,A,0.46,-0.87,2.256,,50,HOO,-1.24333,0.0500837,0.0034616,0.938672 beta-lactamase_0_D113D,beta-lactamase_0_113,TEM-1,beta-lactamase_0,P62593,,YES,113,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.829,-1.829,,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.0500837,0.00474112,0.926181 beta-lactamase_0_D129D,beta-lactamase_0_129,TEM-1,beta-lactamase_0,P62593,,YES,129,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.816,-0.816,,,,,B,0.75,-0.69,2.66,,34.97,PAP,-0.818,0.0500837,0.00109178,0.871891 beta-lactamase_0_D155D,beta-lactamase_0_155,TEM-1,beta-lactamase_0,P62593,,YES,155,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.889,-0.889,,,0.049,,B,0.75,-0.9,16.833,16.833,64.69,OAB,-1.62267,0.0500837,0.00135315,0.889787 beta-lactamase_0_D161D,beta-lactamase_0_161,TEM-1,beta-lactamase_0,P62593,,YES,161,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.891,-0.891,,,0.341,,A,0.75,-0.52,0.795,,61.19,HAB,-0.961333,0.0500837,0.000897697,0.773045 beta-lactamase_0_D174D,beta-lactamase_0_174,TEM-1,beta-lactamase_0,P62593,,YES,174,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.738,-0.738,,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.0500837,0.00125633,0.751789 beta-lactamase_0_D177D,beta-lactamase_0_177,TEM-1,beta-lactamase_0,P62593,,YES,177,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.967,-0.967,,,0.006,T,L,0.75,-1.02,3.536,,64.69,BAP,-0.873667,0.0500837,0.000864022,0.880202 beta-lactamase_0_D207D,beta-lactamase_0_207,TEM-1,beta-lactamase_0,P62593,,YES,207,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.064,-2.064,,,0.409,H,A,0.75,0.12,5.277,,77.62,HAH,-1.77033,0.0500837,0.00592942,0.913069 beta-lactamase_0_D212D,beta-lactamase_0_212,TEM-1,beta-lactamase_0,P62593,,YES,212,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.624,-1.624,,,0.037,,b,0.75,-0.58,3.34,,74.48,HAB,-1.77667,0.0500837,0.00644302,1.04382 beta-lactamase_0_D231D,beta-lactamase_0_231,TEM-1,beta-lactamase_0,P62593,,YES,231,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.816,-0.816,,,,E,B,0.75,-1.06,4.975,,65.38,HAB,-0.994,0.0500837,0.00107395,0.873883 beta-lactamase_0_D252D,beta-lactamase_0_252,TEM-1,beta-lactamase_0,P62593,,YES,252,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.94,-1.94,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.0500837,0.00575769,0.948934 beta-lactamase_0_D271D,beta-lactamase_0_271,TEM-1,beta-lactamase_0,P62593,,YES,271,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.249,-1.249,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.0500837,0.00752082,0.881956 beta-lactamase_0_D33D,beta-lactamase_0_33,TEM-1,beta-lactamase_0,P62593,,YES,33,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.321,-2.321,,,0.366,H,A,0.75,0.33,12.514,12.514,77.62,BAH,-2.12133,0.0500837,0.00435556,0.946672 beta-lactamase_0_D36D,beta-lactamase_0_36,TEM-1,beta-lactamase_0,P62593,,YES,36,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.732,-2.732,,,0.555,H,A,0.75,1.17,13.689,13.689,77.62,AAP,-1.91167,0.0500837,0.00476483,0.89333 beta-lactamase_0_D48D,beta-lactamase_0_48,TEM-1,beta-lactamase_0,P62593,,YES,48,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.101,-1.101,,,0.189,E,B,0.75,0.21,17.825,17.825,50.35,HAH,-1.62467,0.0500837,0.0027273,0.716051 beta-lactamase_0_D83D,beta-lactamase_0_83,TEM-1,beta-lactamase_0,P62593,,YES,83,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.066,-1.066,,,0.354,H,A,0.75,0.22,0.617,,48.95,HAH,-1.34733,0.0500837,0.00205968,0.714828 beta-lactamase_0_D99D,beta-lactamase_0_99,TEM-1,beta-lactamase_0,P62593,,YES,99,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.191,-1.191,,,0.402,G,A,0.75,0.36,0.374,,64.69,PAH,-1.794,0.0500837,0.00305446,1.0049 beta-lactamase_0_E102E,beta-lactamase_0_102,TEM-1,beta-lactamase_0,P62593,,YES,102,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.118,-2.118,,,0.722,S,B,1.04,1.82,4.773,,73.08,HAH,-1.581,0.0500837,0.00486633,0.999562 beta-lactamase_0_E108E,beta-lactamase_0_108,TEM-1,beta-lactamase_0,P62593,,YES,108,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.46,-1.46,,,0.572,G,A,1.04,1.87,8.602,8.602,72.73,PAB,-1.437,0.0500837,0.00413372,0.967382 beta-lactamase_0_E119E,beta-lactamase_0_119,TEM-1,beta-lactamase_0,P62593,,YES,119,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.412,-1.412,,,0.358,H,A,1.04,0.51,3.396,,63.99,BAH,-1.623,0.0500837,0.00386966,0.960291 beta-lactamase_0_E145E,beta-lactamase_0_145,TEM-1,beta-lactamase_0,P62593,,YES,145,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.357,-2.357,,,0.545,H,A,1.04,0.79,1.199,,77.62,BAH,-2.069,0.0500837,0.00553285,0.966676 beta-lactamase_0_E164E,beta-lactamase_0_164,TEM-1,beta-lactamase_0,P62593,,YES,164,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-0.948,-0.948,,,0.011,T,B,1.04,-0.4,1.011,,64.69,HAO,-1.388,0.0500837,0.00137286,0.910965 beta-lactamase_0_E166E,beta-lactamase_0_166,TEM-1,beta-lactamase_0,P62593,,YES,166,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.756,-1.756,,,0.508,G,A,1.04,1.05,17.227,17.227,73.08,OAH,-1.42233,0.0500837,0.00512989,0.949683 beta-lactamase_0_E169E,beta-lactamase_0_169,TEM-1,beta-lactamase_0,P62593,,YES,169,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.23,-1.23,,,0.337,,A,1.04,1,3.516,,73.08,PAH,-1.16533,0.0500837,0.00400994,0.915957 beta-lactamase_0_E175E,beta-lactamase_0_175,TEM-1,beta-lactamase_0,P62593,,YES,175,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.336,-2.336,,,0.551,,A,1.04,1.05,2.334,,77.62,AAB,-1.31233,0.0500837,0.00482205,0.900549 beta-lactamase_0_E195E,beta-lactamase_0_195,TEM-1,beta-lactamase_0,P62593,,YES,195,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.186,-2.186,,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.0500837,0.00496565,0.888535 beta-lactamase_0_E210E,beta-lactamase_0_210,TEM-1,beta-lactamase_0,P62593,,YES,210,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.319,-2.319,,,0.476,H,A,1.04,0.75,3.618,,77.62,HAH,-1.88567,0.0500837,0.00663582,1.03987 beta-lactamase_0_E238E,beta-lactamase_0_238,TEM-1,beta-lactamase_0,P62593,,YES,238,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.002,-2.002,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.0500837,0.00743256,0.943721 beta-lactamase_0_E26E,beta-lactamase_0_26,TEM-1,beta-lactamase_0,P62593,,YES,26,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.454,-2.454,,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.0500837,0.00297948,0.885938 beta-lactamase_0_E272E,beta-lactamase_0_272,TEM-1,beta-lactamase_0,P62593,,YES,272,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.127,-1.127,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.0500837,0.00545371,0.975597 beta-lactamase_0_E279E,beta-lactamase_0_279,TEM-1,beta-lactamase_0,P62593,,YES,279,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.038,-1.038,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.0500837,0.0192826,0.929188 beta-lactamase_0_E35E,beta-lactamase_0_35,TEM-1,beta-lactamase_0,P62593,,YES,35,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-0.869,-0.869,,,0.15,H,A,1.04,0.21,0.664,,46.85,HAA,-1.88667,0.0500837,0.00174441,0.727965 beta-lactamase_0_E46E,beta-lactamase_0_46,TEM-1,beta-lactamase_0,P62593,,YES,46,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.94,-1.94,,,0.021,E,B,1.04,0.14,30.306,30.306,59.44,HAH,-2.079,0.0500837,0.00427568,0.848027 beta-lactamase_0_E56E,beta-lactamase_0_56,TEM-1,beta-lactamase_0,P62593,,YES,56,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.043,-2.043,,,0.198,E,B,1.04,0.31,1.491,,72.73,HAP,-1.94033,0.0500837,0.00238534,0.899374 beta-lactamase_0_E61E,beta-lactamase_0_61,TEM-1,beta-lactamase_0,P62593,,YES,61,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.115,-2.115,,,0.775,T,a,1.04,1.29,34.763,34.763,77.62,OAA,-1.92567,0.0500837,0.00440955,0.972534 beta-lactamase_0_E62E,beta-lactamase_0_62,TEM-1,beta-lactamase_0,P62593,,YES,62,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.193,-1.193,,,0.342,S,B,1.04,-0.3,5.784,,73.08,AAB,-1.417,0.0500837,0.00264802,0.951635 beta-lactamase_0_E87E,beta-lactamase_0_87,TEM-1,beta-lactamase_0,P62593,,YES,87,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.421,-1.421,,,0.048,,B,1.04,0.92,1.159,,64.69,PAP,-1.969,0.0500837,0.00337888,1.0143 beta-lactamase_0_F149F,beta-lactamase_0_149,TEM-1,beta-lactamase_0,P62593,,YES,149,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.299,-1.299,,,0.195,H,A,0.58,0.11,3.518,,63.99,HHH,-1.46067,0.0500837,0.00418462,0.975292 beta-lactamase_0_F228F,beta-lactamase_0_228,TEM-1,beta-lactamase_0,P62593,,YES,228,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-2.342,-2.342,,,0.154,E,B,0.58,-0.42,15.504,15.504,63.29,HHH,-1.53033,0.0500837,0.0046669,0.994796 beta-lactamase_0_F58F,beta-lactamase_0_58,TEM-1,beta-lactamase_0,P62593,,YES,58,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-2.914,-2.914,,,0.266,E,B,0.58,-0.07,24.637,24.637,77.62,PHB,-2.059,0.0500837,0.00523369,0.981338 beta-lactamase_0_F64F,beta-lactamase_0_64,TEM-1,beta-lactamase_0,P62593,,YES,64,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-0.841,-0.841,,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.0500837,0.000947691,0.854609 beta-lactamase_0_F70F,beta-lactamase_0_70,TEM-1,beta-lactamase_0,P62593,,YES,70,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.169,-1.169,,,,H,A,0.58,-1.34,2.153,,63.99,PHB,-0.980667,0.0500837,0.00193499,0.897126 beta-lactamase_0_G114G,beta-lactamase_0_114,TEM-1,beta-lactamase_0,P62593,,YES,114,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.094,-1.094,,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.0500837,0.00224919,0.840495 beta-lactamase_0_G141G,beta-lactamase_0_141,TEM-1,beta-lactamase_0,P62593,,YES,141,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.828,-0.828,,,0.575,T,l,0.29,-0.28,0.722,,64.69,HOO,-1.08933,0.0500837,0.0012419,0.863886 beta-lactamase_0_G142G,beta-lactamase_0_142,TEM-1,beta-lactamase_0,P62593,,YES,142,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.707,-0.707,,,0.034,,p,0.29,-0.64,1.947,,64.69,OOO,-0.834,0.0500837,0.00060149,0.880267 beta-lactamase_0_G154G,beta-lactamase_0_154,TEM-1,beta-lactamase_0,P62593,,YES,154,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.823,-0.823,,,0.54,T,l,0.29,-0.56,3.629,,64.69,HOA,-1.635,0.0500837,0.00180205,0.856122 beta-lactamase_0_G194G,beta-lactamase_0_194,TEM-1,beta-lactamase_0,P62593,,YES,194,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.396,-1.396,,,0.276,S,b,0.29,0.36,3.017,,67.83,POA,-1.832,0.0500837,0.00392163,0.920495 beta-lactamase_0_G216G,beta-lactamase_0_216,TEM-1,beta-lactamase_0,P62593,,YES,216,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.477,-1.477,,,0.437,I,A,0.29,-0.58,0.834,,74.48,HOO,-1.68067,0.0500837,0.00639568,0.989887 beta-lactamase_0_G226G,beta-lactamase_0_226,TEM-1,beta-lactamase_0,P62593,,YES,226,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.461,-1.461,,,0.701,T,l,0.29,-0.25,23.034,23.034,74.48,HOH,-1.42933,0.0500837,0.00665294,0.918821 beta-lactamase_0_G234G,beta-lactamase_0_234,TEM-1,beta-lactamase_0,P62593,,YES,234,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.62,-0.62,,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.0500837,0.000889577,0.891379 beta-lactamase_0_G236G,beta-lactamase_0_236,TEM-1,beta-lactamase_0,P62593,,YES,236,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.784,-0.784,,,0.241,,b,0.29,-0.59,3.506,,64.69,HOO,-1.025,0.0500837,0.00162372,0.939349 beta-lactamase_0_G240G,beta-lactamase_0_240,TEM-1,beta-lactamase_0,P62593,,YES,240,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.537,-1.537,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.0500837,0.00591201,0.960628 beta-lactamase_0_G243G,beta-lactamase_0_243,TEM-1,beta-lactamase_0,P62593,,YES,243,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.532,-1.532,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.0500837,0.00464034,0.887804 beta-lactamase_0_G249G,beta-lactamase_0_249,TEM-1,beta-lactamase_0,P62593,,YES,249,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.312,-1.312,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.0500837,0.00220169,0.908023 beta-lactamase_0_G253G,beta-lactamase_0_253,TEM-1,beta-lactamase_0,P62593,,YES,253,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-2.253,-2.253,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.0500837,0.00786358,1.06017 beta-lactamase_0_G265G,beta-lactamase_0_265,TEM-1,beta-lactamase_0,P62593,,YES,265,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-2.58,-2.58,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.0500837,0.00811926,0.936098 beta-lactamase_0_G281G,beta-lactamase_0_281,TEM-1,beta-lactamase_0,P62593,,YES,281,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-2.247,-2.247,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.0500837,0.0406482,0.947248 beta-lactamase_0_G39G,beta-lactamase_0_39,TEM-1,beta-lactamase_0,P62593,,YES,39,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.864,-1.864,,,0.701,T,L,0.29,0.47,4.111,,77.62,HOH,-1.53633,0.0500837,0.00487611,0.896256 beta-lactamase_0_G43G,beta-lactamase_0_43,TEM-1,beta-lactamase_0,P62593,,YES,43,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.62,-0.62,,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.0500837,0.00120151,0.885681 beta-lactamase_0_G52G,beta-lactamase_0_52,TEM-1,beta-lactamase_0,P62593,,YES,52,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.149,-1.149,,,0.299,,l,0.29,-0.04,1.164,,64.69,POB,-1.66267,0.0500837,0.00340138,0.866992 beta-lactamase_0_G76G,beta-lactamase_0_76,TEM-1,beta-lactamase_0,P62593,,YES,76,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.189,-1.189,,,,H,A,0.29,-0.67,1.188,,67.83,OOH,-1.22267,0.0500837,0.00476637,0.846556 beta-lactamase_0_G85G,beta-lactamase_0_85,TEM-1,beta-lactamase_0,P62593,,YES,85,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.011,-1.011,,,0.805,T,l,0.29,1.7,2.25,,63.64,HOP,-1.68733,0.0500837,0.00252173,0.847956 beta-lactamase_0_G90G,beta-lactamase_0_90,TEM-1,beta-lactamase_0,P62593,,YES,90,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-2.091,-2.091,,,0.598,T,A,0.29,0.32,2.04,,77.62,HOB,-1.52633,0.0500837,0.00490273,0.917005 beta-lactamase_0_H110H,beta-lactamase_0_110,TEM-1,beta-lactamase_0,P62593,,YES,110,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-1.706,-1.706,,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.0500837,0.00441499,1.02776 beta-lactamase_0_H151H,beta-lactamase_0_151,TEM-1,beta-lactamase_0,P62593,,YES,151,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-2.96,-2.96,,,0.594,H,A,0.17,0.1,9.375,,77.62,HBP,-2.34767,0.0500837,0.00216946,0.864514 beta-lactamase_0_H156H,beta-lactamase_0_156,TEM-1,beta-lactamase_0,P62593,,YES,156,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-3.156,-3.156,,,0.753,S,A,0.17,-0.6,23.367,23.367,77.62,ABH,-1.932,0.0500837,0.00468596,0.935548 beta-lactamase_0_H24H,beta-lactamase_0_24,TEM-1,beta-lactamase_0,P62593,,YES,24,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-2.481,-2.481,,,,,,,,2.708,,93.01,OBO,-2.0035,0.0500837,0.00238894,0.936769 beta-lactamase_0_H287H,beta-lactamase_0_287,TEM-1,beta-lactamase_0,P62593,,YES,287,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,,,,,,,,,,,,,BBH,-1.111,0.0500837,,0.901036 beta-lactamase_0_H94H,beta-lactamase_0_94,TEM-1,beta-lactamase_0,P62593,,YES,94,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-2.5,-2.5,,,0.776,,B,0.17,1.24,1.176,,77.62,HBH,-1.872,0.0500837,0.00389226,0.986679 beta-lactamase_0_I125I,beta-lactamase_0_125,TEM-1,beta-lactamase_0,P62593,,YES,125,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.441,-1.441,,,,H,A,0.48,-0.7,1.874,,63.29,HHP,-1.248,0.0500837,0.00383964,0.881695 beta-lactamase_0_I140I,beta-lactamase_0_140,TEM-1,beta-lactamase_0,P62593,,YES,140,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.733,-1.733,,,0.128,H,A,0.48,0.41,4.714,,73.08,PHO,-1.48733,0.0500837,0.00597777,0.97327 beta-lactamase_0_I171I,beta-lactamase_0_171,TEM-1,beta-lactamase_0,P62593,,YES,171,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-2.431,-2.431,,,0.361,,B,0.48,0.53,16.954,16.954,77.62,HHO,-1.55533,0.0500837,0.00623355,0.916651 beta-lactamase_0_I206I,beta-lactamase_0_206,TEM-1,beta-lactamase_0,P62593,,YES,206,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-2.429,-2.429,,,0.173,H,A,0.48,-0.34,3.411,,77.62,HHA,-1.805,0.0500837,0.00528934,0.970735 beta-lactamase_0_I229I,beta-lactamase_0_229,TEM-1,beta-lactamase_0,P62593,,YES,229,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.267,-1.267,,,0.083,E,B,0.48,-0.76,1.69,,50,HHH,-1.58767,0.0500837,0.00477249,0.862312 beta-lactamase_0_I244I,beta-lactamase_0_244,TEM-1,beta-lactamase_0,P62593,,YES,244,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.555,-1.555,,,,E,B,0.48,-0.84,1.241,,77.62,OHH,-1.385,0.0500837,0.00605379,0.985694 beta-lactamase_0_I245I,beta-lactamase_0_245,TEM-1,beta-lactamase_0,P62593,,YES,245,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.068,-1.068,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.0500837,0.00391032,0.958192 beta-lactamase_0_I258I,beta-lactamase_0_258,TEM-1,beta-lactamase_0,P62593,,YES,258,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.975,-1.975,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.0500837,0.007931,0.993998 beta-lactamase_0_I261I,beta-lactamase_0_261,TEM-1,beta-lactamase_0,P62593,,YES,261,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-2.88,-2.88,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.0500837,0.0123091,0.903324 beta-lactamase_0_I277I,beta-lactamase_0_277,TEM-1,beta-lactamase_0,P62593,,YES,277,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.869,-1.869,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.0500837,0.0169305,0.933602 beta-lactamase_0_I280I,beta-lactamase_0_280,TEM-1,beta-lactamase_0,P62593,,YES,280,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.708,-1.708,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.0500837,0.0530888,0.988142 beta-lactamase_0_I285I,beta-lactamase_0_285,TEM-1,beta-lactamase_0,P62593,,YES,285,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.845,-1.845,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.0500837,0.101555,0.984501 beta-lactamase_0_I45I,beta-lactamase_0_45,TEM-1,beta-lactamase_0,P62593,,YES,45,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-2.421,-2.421,,,,E,B,0.48,-0.3,1.375,,77.62,HHA,-2.30267,0.0500837,0.00452842,0.891202 beta-lactamase_0_I54I,beta-lactamase_0_54,TEM-1,beta-lactamase_0,P62593,,YES,54,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-2.838,-2.838,,,0.669,E,B,0.48,-0.14,0.541,,73.78,BHH,-2.337,0.0500837,0.00403589,0.890508 beta-lactamase_0_I93I,beta-lactamase_0_93,TEM-1,beta-lactamase_0,P62593,,YES,93,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.401,-1.401,,,0.128,E,B,0.48,0.44,1.266,,67.83,BHB,-1.873,0.0500837,0.00527066,0.971513 beta-lactamase_0_K109K,beta-lactamase_0_109,TEM-1,beta-lactamase_0,P62593,,YES,109,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.734,-1.734,,,0.787,G,A,2.34,2.21,15.473,15.473,72.73,ABB,-1.63333,0.0500837,0.00462493,0.932841 beta-lactamase_0_K144K,beta-lactamase_0_144,TEM-1,beta-lactamase_0,P62593,,YES,144,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-2.388,-2.388,,,0.863,H,A,2.34,1.27,5.696,,77.62,OBA,-1.904,0.0500837,0.00481141,0.895261 beta-lactamase_0_K190K,beta-lactamase_0_190,TEM-1,beta-lactamase_0,P62593,,YES,190,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.994,-1.994,,,0.371,H,A,2.34,0.16,16.606,16.606,77.62,BBH,-1.64167,0.0500837,0.00574527,0.987525 beta-lactamase_0_K213K,beta-lactamase_0_213,TEM-1,beta-lactamase_0,P62593,,YES,213,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.81,-1.81,,,0.67,,A,2.34,0.29,3.015,,67.83,ABH,-1.57767,0.0500837,0.00610411,0.937547 beta-lactamase_0_K232K,beta-lactamase_0_232,TEM-1,beta-lactamase_0,P62593,,YES,232,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.012,-1.012,,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.0500837,0.00313441,0.974236 beta-lactamase_0_K254K,beta-lactamase_0_254,TEM-1,beta-lactamase_0,P62593,,YES,254,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-2.126,-2.126,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.0500837,0.00369,1.00624 beta-lactamase_0_K286K,beta-lactamase_0_286,TEM-1,beta-lactamase_0,P62593,,YES,286,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.111,-1.111,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.0500837,,0.839886 beta-lactamase_0_K30K,beta-lactamase_0_30,TEM-1,beta-lactamase_0,P62593,,YES,30,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-2.307,-2.307,,,0.142,H,A,2.34,-0.65,1.491,,93.01,HBH,-2.32833,0.0500837,0.00448593,0.995999 beta-lactamase_0_K32K,beta-lactamase_0_32,TEM-1,beta-lactamase_0,P62593,,YES,32,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.984,-1.984,,,0.563,H,A,2.34,0.34,0.418,,73.08,HBA,-2.04233,0.0500837,0.00401283,0.896037 beta-lactamase_0_K53K,beta-lactamase_0_53,TEM-1,beta-lactamase_0,P62593,,YES,53,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-2.313,-2.313,,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.0500837,0.00383383,0.891878 beta-lactamase_0_K71K,beta-lactamase_0_71,TEM-1,beta-lactamase_0,P62593,,YES,71,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-0.8,-0.8,,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.0500837,0.00103192,0.795943 beta-lactamase_0_L100L,beta-lactamase_0_100,TEM-1,beta-lactamase_0,P62593,,YES,100,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.218,-1.218,,,0.343,,B,0.55,0.13,1.373,,63.29,AHH,-1.23467,0.0500837,0.00413885,0.963226 beta-lactamase_0_L111L,beta-lactamase_0_111,TEM-1,beta-lactamase_0,P62593,,YES,111,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.76,-1.76,,,0.328,T,A,0.55,0.93,1.966,,64.34,BHP,-1.884,0.0500837,0.00480671,0.878669 beta-lactamase_0_L120L,beta-lactamase_0_120,TEM-1,beta-lactamase_0,P62593,,YES,120,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.044,-1.044,,,,H,A,0.55,-1.13,1.2,,64.69,AHO,-1.13633,0.0500837,0.00143563,0.875112 beta-lactamase_0_L135L,beta-lactamase_0_135,TEM-1,beta-lactamase_0,P62593,,YES,135,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.002,-1.002,,,0.117,H,A,0.55,-0.58,0.705,,43.71,PHH,-1.03767,0.0500837,0.00244423,0.908074 beta-lactamase_0_L136L,beta-lactamase_0_136,TEM-1,beta-lactamase_0,P62593,,YES,136,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.232,-1.232,,,,H,A,0.55,-0.34,0.648,,48.95,HHH,-1.088,0.0500837,0.00442304,0.837071 beta-lactamase_0_L137L,beta-lactamase_0_137,TEM-1,beta-lactamase_0,P62593,,YES,137,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.03,-1.03,,,,H,A,0.55,-0.38,0.328,,42.31,HHP,-1.58933,0.0500837,0.00278599,0.866578 beta-lactamase_0_L146L,beta-lactamase_0_146,TEM-1,beta-lactamase_0,P62593,,YES,146,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.462,-1.462,,,0.007,H,A,0.55,-0.56,2.051,,64.69,AHP,-1.656,0.0500837,0.00474542,0.890064 beta-lactamase_0_L150L,beta-lactamase_0_150,TEM-1,beta-lactamase_0,P62593,,YES,150,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.326,-1.326,,,,H,A,0.55,-0.2,2.128,,62.94,HHB,-1.86167,0.0500837,0.00463171,0.861155 beta-lactamase_0_L160L,beta-lactamase_0_160,TEM-1,beta-lactamase_0,P62593,,YES,160,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.977,-0.977,,,0.022,,B,0.55,-0.6,0.68,,44.41,BHA,-0.936,0.0500837,0.00193775,0.906056 beta-lactamase_0_L167L,beta-lactamase_0_167,TEM-1,beta-lactamase_0,P62593,,YES,167,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.138,-1.138,,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.0500837,0.00303566,0.913375 beta-lactamase_0_L188L,beta-lactamase_0_188,TEM-1,beta-lactamase_0,P62593,,YES,188,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.166,-1.166,,,,H,A,0.55,-0.3,2.739,,60.14,PHB,-1.47033,0.0500837,0.00295687,0.924507 beta-lactamase_0_L191L,beta-lactamase_0_191,TEM-1,beta-lactamase_0,P62593,,YES,191,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.087,-1.087,,,,H,A,0.55,0.09,12.255,12.255,63.29,BHH,-1.445,0.0500837,0.00263549,0.863411 beta-lactamase_0_L192L,beta-lactamase_0_192,TEM-1,beta-lactamase_0,P62593,,YES,192,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.254,-1.254,,,0.095,H,A,0.55,0.35,1.756,,60.14,HHP,-1.41833,0.0500837,0.00558728,0.88765 beta-lactamase_0_L196L,beta-lactamase_0_196,TEM-1,beta-lactamase_0,P62593,,YES,196,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-2.478,-2.478,,,0.518,S,A,0.55,1.35,6.513,6.513,77.62,AHH,-1.839,0.0500837,0.00512144,0.981258 beta-lactamase_0_L197L,beta-lactamase_0_197,TEM-1,beta-lactamase_0,P62593,,YES,197,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.853,-0.853,,,0.007,S,B,0.55,0.33,1.087,,60.14,HHP,-1.833,0.0500837,0.00144602,0.779583 beta-lactamase_0_L199L,beta-lactamase_0_199,TEM-1,beta-lactamase_0,P62593,,YES,199,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-2.942,-2.942,,,0.832,H,A,0.55,0.42,10.85,10.85,77.62,PHH,-2.32933,0.0500837,0.0048649,0.905879 beta-lactamase_0_L205L,beta-lactamase_0_205,TEM-1,beta-lactamase_0,P62593,,YES,205,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.922,-0.922,,,,H,A,0.55,-0.46,1.065,,42.31,PHH,-1.57767,0.0500837,0.00255802,0.907389 beta-lactamase_0_L218L,beta-lactamase_0_218,TEM-1,beta-lactamase_0,P62593,,YES,218,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.391,-1.391,,,,I,b,0.55,-0.53,28.707,28.707,74.48,OHH,-1.58867,0.0500837,0.00618274,0.920856 beta-lactamase_0_L219L,beta-lactamase_0_219,TEM-1,beta-lactamase_0,P62593,,YES,219,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.313,-1.313,,,,I,A,0.55,-0.51,6.513,6.513,74.48,HHB,-1.21533,0.0500837,0.00664345,0.936173 beta-lactamase_0_L223L,beta-lactamase_0_223,TEM-1,beta-lactamase_0,P62593,,YES,223,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.055,-1.055,,,0.27,,B,0.55,0.09,1.633,,74.48,HHO,-1.35033,0.0500837,0.00372793,0.88321 beta-lactamase_0_L248L,beta-lactamase_0_248,TEM-1,beta-lactamase_0,P62593,,YES,248,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.794,-1.794,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.0500837,0.00428493,0.910263 beta-lactamase_0_L284L,beta-lactamase_0_284,TEM-1,beta-lactamase_0,P62593,,YES,284,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.981,-1.981,,,0.848,H,A,2.89,0.67,4.544,,77.62,PHH,-1.82133,0.0500837,0.0686156,0.932246 beta-lactamase_0_L28L,beta-lactamase_0_28,TEM-1,beta-lactamase_0,P62593,,YES,28,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.579,-1.579,,,0.277,H,A,0.55,-0.16,9.35,9.35,93.01,PHH,-2.11333,0.0500837,0.00359321,0.890118 beta-lactamase_0_L38L,beta-lactamase_0_38,TEM-1,beta-lactamase_0,P62593,,YES,38,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.343,-1.343,,,0.088,H,A,0.55,0.2,13.556,13.556,64.34,PHO,-1.78033,0.0500837,0.00373244,0.913192 beta-lactamase_0_L47L,beta-lactamase_0_47,TEM-1,beta-lactamase_0,P62593,,YES,47,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.876,-1.876,,,0.007,E,B,0.55,0.2,1.024,,67.83,AHA,-1.639,0.0500837,0.00439844,0.800506 beta-lactamase_0_L49L,beta-lactamase_0_49,TEM-1,beta-lactamase_0,P62593,,YES,49,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.897,-1.897,,,0.131,T,A,0.55,0.04,13.838,13.838,64.69,AHP,-1.99233,0.0500837,0.00401477,0.907996 beta-lactamase_0_L55L,beta-lactamase_0_55,TEM-1,beta-lactamase_0,P62593,,YES,55,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.86,-1.86,,,0.372,E,A,0.55,-0.36,1.967,,63.99,HHA,-2.247,0.0500837,0.00403741,0.926208 beta-lactamase_0_L73L,beta-lactamase_0_73,TEM-1,beta-lactamase_0,P62593,,YES,73,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.507,-1.507,,,,H,A,0.55,-0.64,0.877,,67.83,HHH,-1.487,0.0500837,0.00488983,0.907484 beta-lactamase_0_L74L,beta-lactamase_0_74,TEM-1,beta-lactamase_0,P62593,,YES,74,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.296,-1.296,,,,H,A,0.55,-0.91,1.46,,50,HHO,-1.34933,0.0500837,0.00493255,0.914284 beta-lactamase_0_L79L,beta-lactamase_0_79,TEM-1,beta-lactamase_0,P62593,,YES,79,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.842,-0.842,,,0.007,H,A,0.55,-0.16,5.053,,50.35,HHP,-1.44333,0.0500837,0.000947397,0.807327 beta-lactamase_0_L89L,beta-lactamase_0_89,TEM-1,beta-lactamase_0,P62593,,YES,89,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.096,-1.096,,,0.168,T,A,0.55,0.63,2.373,,64.34,PHO,-1.75767,0.0500837,0.00207068,0.850343 beta-lactamase_0_M115M,beta-lactamase_0_115,TEM-1,beta-lactamase_0,P62593,,YES,115,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.389,-1.389,,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.0500837,0.0034337,0.790281 beta-lactamase_0_M127M,beta-lactamase_0_127,TEM-1,beta-lactamase_0,P62593,,YES,127,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-2.251,-2.251,,,0.312,S,A,0.55,0.32,9.35,9.35,72.73,PHP,-1.40433,0.0500837,0.00437927,1.52383 beta-lactamase_0_M153M,beta-lactamase_0_153,TEM-1,beta-lactamase_0,P62593,,YES,153,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-3.193,-3.193,,,0.14,T,A,0.55,-0.11,3.826,,77.62,PHO,-2.25767,0.0500837,0.00509109,1.15548 beta-lactamase_0_M180M,beta-lactamase_0_180,TEM-1,beta-lactamase_0,P62593,,YES,180,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-2.795,-2.795,,,0.242,,B,0.55,-0.94,2.892,,77.62,PHO,-1.56433,0.0500837,0.00552048,1.06583 beta-lactamase_0_M184M,beta-lactamase_0_184,TEM-1,beta-lactamase_0,P62593,,YES,184,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.593,-1.593,,,,H,A,0.55,-0.87,13.292,13.292,62.94,HHH,-1.41,0.0500837,0.00356019,0.918994 beta-lactamase_0_M209M,beta-lactamase_0_209,TEM-1,beta-lactamase_0,P62593,,YES,209,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.442,-1.442,,,,H,A,0.55,-0.97,3.876,,64.69,HHA,-1.52633,0.0500837,0.00625021,0.939427 beta-lactamase_0_M270M,beta-lactamase_0_270,TEM-1,beta-lactamase_0,P62593,,YES,270,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.723,-1.723,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.0500837,0.00767762,1.32781 beta-lactamase_0_M66M,beta-lactamase_0_66,TEM-1,beta-lactamase_0,P62593,,YES,66,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.362,-1.362,,,0.013,,A,0.55,-0.7,1.204,,73.08,OHH,-1.49567,0.0500837,0.00412876,0.898741 beta-lactamase_0_M67M,beta-lactamase_0_67,TEM-1,beta-lactamase_0,P62593,,YES,67,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-2.231,-2.231,,,0.006,G,P,0.55,-0.81,24.165,24.165,65.03,HHP,-1.502,0.0500837,0.00409753,0.98399 beta-lactamase_0_N130N,beta-lactamase_0_130,TEM-1,beta-lactamase_0,P62593,,YES,130,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-0.798,-0.798,,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.0500837,0.000683376,0.899085 beta-lactamase_0_N134N,beta-lactamase_0_134,TEM-1,beta-lactamase_0,P62593,,YES,134,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-0.879,-0.879,,,0.138,H,A,0.61,-0.6,3.776,,53.15,HPH,-1.02233,0.0500837,0.000644786,0.788657 beta-lactamase_0_N152N,beta-lactamase_0_152,TEM-1,beta-lactamase_0,P62593,,YES,152,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-2.757,-2.757,,,0.863,H,A,0.61,0.92,2.151,,77.62,BPH,-2.97,0.0500837,0.00471429,0.905471 beta-lactamase_0_N168N,beta-lactamase_0_168,TEM-1,beta-lactamase_0,P62593,,YES,168,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-1.029,-1.029,,,0.113,G,A,0.61,-0.4,0.881,,44.41,HPA,-1.13233,0.0500837,0.00288667,0.91064 beta-lactamase_0_N173N,beta-lactamase_0_173,TEM-1,beta-lactamase_0,P62593,,YES,173,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-2.663,-2.663,,,1.044,T,l,0.61,1.25,1.133,,77.62,OPA,-1.46633,0.0500837,0.0033769,0.904038 beta-lactamase_0_N274N,beta-lactamase_0_274,TEM-1,beta-lactamase_0,P62593,,YES,274,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-2.082,-2.082,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.0500837,0.0110418,0.884677 beta-lactamase_0_N50N,beta-lactamase_0_50,TEM-1,beta-lactamase_0,P62593,,YES,50,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-2.979,-2.979,,,0.912,T,A,0.61,1.24,9.874,9.874,77.62,HPP,-2.134,0.0500837,0.0047211,0.895017 beta-lactamase_0_N98N,beta-lactamase_0_98,TEM-1,beta-lactamase_0,P62593,,YES,98,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-2.973,-2.973,,,0.963,G,A,0.61,1.35,14.853,14.853,77.62,PPA,-2.07867,0.0500837,0.00505389,0.918825 beta-lactamase_0_P105P,beta-lactamase_0_105,TEM-1,beta-lactamase_0,P62593,,YES,105,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.813,-0.813,,,0.226,T,A,0.52,0.8,3.48,,63.29,POH,-1.01533,0.0500837,0.0011981,0.764286 beta-lactamase_0_P143P,beta-lactamase_0_143,TEM-1,beta-lactamase_0,P62593,,YES,143,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.967,-0.967,,,0.075,H,A,0.52,-0.37,11.868,11.868,66.78,OOB,-1.354,0.0500837,0.00114551,0.795458 beta-lactamase_0_P165P,beta-lactamase_0_165,TEM-1,beta-lactamase_0,P62593,,YES,165,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.373,-1.373,,,0.203,T,A,0.52,-0.31,3.242,,73.78,AOA,-1.359,0.0500837,0.00549538,0.84244 beta-lactamase_0_P172P,beta-lactamase_0_172,TEM-1,beta-lactamase_0,P62593,,YES,172,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.998,-0.998,,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.0500837,0.00312594,0.816765 beta-lactamase_0_P181P,beta-lactamase_0_181,TEM-1,beta-lactamase_0,P62593,,YES,181,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.813,-0.813,,,,H,A,0.52,-1.14,1.357,,61.54,HOH,-1.795,0.0500837,0.000703122,0.804529 beta-lactamase_0_P217P,beta-lactamase_0_217,TEM-1,beta-lactamase_0,P62593,,YES,217,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-2.062,-2.062,,,0.496,I,A,0.52,-0.33,1.087,,74.48,OOH,-1.64333,0.0500837,0.00463211,0.879346 beta-lactamase_0_P224P,beta-lactamase_0_224,TEM-1,beta-lactamase_0,P62593,,YES,224,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.893,-0.893,,,0.383,,B,0.52,-0.3,3.587,,74.48,HOH,-1.26433,0.0500837,0.00189564,0.792377 beta-lactamase_0_P250P,beta-lactamase_0_250,TEM-1,beta-lactamase_0,P62593,,YES,250,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-2.335,-2.335,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.0500837,0.00550899,0.918071 beta-lactamase_0_P255P,beta-lactamase_0_255,TEM-1,beta-lactamase_0,P62593,,YES,255,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-2.266,-2.266,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.0500837,0.00499612,0.826878 beta-lactamase_0_P25P,beta-lactamase_0_25,TEM-1,beta-lactamase_0,P62593,,YES,25,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.526,-1.526,,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.0500837,0.00347571,0.872644 beta-lactamase_0_P60P,beta-lactamase_0_60,TEM-1,beta-lactamase_0,P62593,,YES,60,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-2.469,-2.469,,,0.256,T,A,0.52,-0.56,3.653,,77.62,BOA,-1.97633,0.0500837,0.00521318,0.934845 beta-lactamase_0_P65P,beta-lactamase_0_65,TEM-1,beta-lactamase_0,P62593,,YES,65,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.894,-0.894,,,0.098,E,B,0.52,-0.62,0.663,,40.56,HOH,-1.03233,0.0500837,0.00152776,0.808478 beta-lactamase_0_Q203Q,beta-lactamase_0_203,TEM-1,beta-lactamase_0,P62593,,YES,203,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.168,-2.168,,,0.47,H,A,0.64,-0.38,14.541,14.541,65.38,BPP,-1.614,0.0500837,0.00631514,0.997137 beta-lactamase_0_Q204Q,beta-lactamase_0_204,TEM-1,beta-lactamase_0,P62593,,YES,204,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-1.382,-1.382,,,0.204,H,A,0.64,0.09,2.646,,66.08,PPH,-1.49067,0.0500837,0.00364106,0.912211 beta-lactamase_0_Q267Q,beta-lactamase_0_267,TEM-1,beta-lactamase_0,P62593,,YES,267,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.308,-2.308,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.0500837,0.0102128,0.935315 beta-lactamase_0_Q276Q,beta-lactamase_0_276,TEM-1,beta-lactamase_0,P62593,,YES,276,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-1.144,-1.144,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.0500837,0.0191712,0.913244 beta-lactamase_0_Q37Q,beta-lactamase_0_37,TEM-1,beta-lactamase_0,P62593,,YES,37,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.134,-2.134,,,0.613,H,A,0.64,1.98,4.001,,73.08,APH,-2.06967,0.0500837,0.00425833,0.933685 beta-lactamase_0_Q86Q,beta-lactamase_0_86,TEM-1,beta-lactamase_0,P62593,,YES,86,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.4,-2.4,,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.0500837,0.00450027,0.981923 beta-lactamase_0_Q88Q,beta-lactamase_0_88,TEM-1,beta-lactamase_0,P62593,,YES,88,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.086,-2.086,,,0.807,,B,0.64,2.03,0.4,,77.62,APH,-1.53433,0.0500837,0.00504167,0.916196 beta-lactamase_0_Q97Q,beta-lactamase_0_97,TEM-1,beta-lactamase_0,P62593,,YES,97,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.072,-2.072,,,0.823,G,A,0.64,2.42,16.954,16.954,77.62,PPP,-2.43833,0.0500837,0.0045116,0.859886 beta-lactamase_0_R118R,beta-lactamase_0_118,TEM-1,beta-lactamase_0,P62593,,YES,118,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.413,-2.413,,,0.457,H,A,1.2,1.39,3.961,,77.62,HBA,-1.785,0.0500837,0.00538794,1.00208 beta-lactamase_0_R159R,beta-lactamase_0_159,TEM-1,beta-lactamase_0,P62593,,YES,159,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-0.94,-0.94,,,0.316,,B,1.2,-0.55,1.426,,64.34,PBH,-1.011,0.0500837,0.00108472,0.904862 beta-lactamase_0_R162R,beta-lactamase_0_162,TEM-1,beta-lactamase_0,P62593,,YES,162,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.016,-1.016,,,0.124,S,B,1.2,-0.37,1.026,,64.69,ABH,-1.25,0.0500837,0.000561334,0.900969 beta-lactamase_0_R176R,beta-lactamase_0_176,TEM-1,beta-lactamase_0,P62593,,YES,176,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-0.863,-0.863,,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.0500837,0.00105554,0.76788 beta-lactamase_0_R189R,beta-lactamase_0_189,TEM-1,beta-lactamase_0,P62593,,YES,189,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.844,-1.844,,,0.278,H,A,1.2,1.01,12.11,12.11,72.73,HBB,-1.668,0.0500837,0.0050699,1.00857 beta-lactamase_0_R202R,beta-lactamase_0_202,TEM-1,beta-lactamase_0,P62593,,YES,202,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.292,-1.292,,,0.188,H,A,1.2,0.62,7.016,,77.62,PBP,-1.54767,0.0500837,0.00321899,0.91156 beta-lactamase_0_R220R,beta-lactamase_0_220,TEM-1,beta-lactamase_0,P62593,,YES,220,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-0.942,-0.942,,,0.295,I,A,1.2,-0.76,21.573,21.573,74.48,HBP,-1.33633,0.0500837,0.00232421,0.929676 beta-lactamase_0_R239R,beta-lactamase_0_239,TEM-1,beta-lactamase_0,P62593,,YES,239,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-0.819,-0.819,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.0500837,0.00213852,0.847043 beta-lactamase_0_R242R,beta-lactamase_0_242,TEM-1,beta-lactamase_0,P62593,,YES,242,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.319,-1.319,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.0500837,0.00452879,0.899737 beta-lactamase_0_R257R,beta-lactamase_0_257,TEM-1,beta-lactamase_0,P62593,,YES,257,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.533,-1.533,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.0500837,0.00756629,0.89263 beta-lactamase_0_R273R,beta-lactamase_0_273,TEM-1,beta-lactamase_0,P62593,,YES,273,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.314,-2.314,,,0.564,H,A,1.2,1.57,20.248,20.248,73.78,ABP,-1.841,0.0500837,0.0077952,0.947719 beta-lactamase_0_R275R,beta-lactamase_0_275,TEM-1,beta-lactamase_0,P62593,,YES,275,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.397,-1.397,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.0500837,0.0141984,0.909851 beta-lactamase_0_R41R,beta-lactamase_0_41,TEM-1,beta-lactamase_0,P62593,,YES,41,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-0.942,-0.942,,,0.321,E,B,1.2,-0.07,2.68,,65.03,HBH,-1.30267,0.0500837,0.00123327,0.919198 beta-lactamase_0_R59R,beta-lactamase_0_59,TEM-1,beta-lactamase_0,P62593,,YES,59,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.345,-1.345,,,0.329,S,L,1.2,-0.09,2.919,,73.08,HBO,-2.24267,0.0500837,0.00318082,0.83502 beta-lactamase_0_R63R,beta-lactamase_0_63,TEM-1,beta-lactamase_0,P62593,,YES,63,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-0.943,-0.943,,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.0500837,0.00126938,0.779038 beta-lactamase_0_R81R,beta-lactamase_0_81,TEM-1,beta-lactamase_0,P62593,,YES,81,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.466,-1.466,,,0.218,H,A,1.2,1.66,0.332,,50,PBH,-1.60667,0.0500837,0.00499763,0.88105 beta-lactamase_0_R91R,beta-lactamase_0_91,TEM-1,beta-lactamase_0,P62593,,YES,91,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.392,-1.392,,,0.444,,B,1.2,0.96,4.557,,50.35,OBB,-1.73367,0.0500837,0.00380226,0.83123 beta-lactamase_0_R92R,beta-lactamase_0_92,TEM-1,beta-lactamase_0,P62593,,YES,92,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.718,-1.718,,,0.479,E,B,1.2,1.36,2.331,,65.38,BBH,-1.50367,0.0500837,0.00429626,0.984401 beta-lactamase_0_S104S,beta-lactamase_0_104,TEM-1,beta-lactamase_0,P62593,,YES,104,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.015,-1.015,,,0.04,,b,0.27,0.57,1.148,,63.29,HPO,-1.05267,0.0500837,0.00218083,0.924042 beta-lactamase_0_S122S,beta-lactamase_0_122,TEM-1,beta-lactamase_0,P62593,,YES,122,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.406,-2.406,,,0.352,H,A,0.27,-0.54,30.794,30.794,77.62,OPH,-1.39767,0.0500837,0.00497825,1.62841 beta-lactamase_0_S128S,beta-lactamase_0_128,TEM-1,beta-lactamase_0,P62593,,YES,128,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-0.84,-0.84,,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.0500837,0.00071483,0.652856 beta-lactamase_0_S201S,beta-lactamase_0_201,TEM-1,beta-lactamase_0,P62593,,YES,201,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.183,-1.183,,,0.064,H,A,0.27,-0.07,3.54,,64.69,HPB,-1.451,0.0500837,0.00198815,0.935371 beta-lactamase_0_S221S,beta-lactamase_0_221,TEM-1,beta-lactamase_0,P62593,,YES,221,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.754,-1.754,,,0.624,H,A,0.27,-0.2,2.914,,74.48,BPH,-1.59967,0.0500837,0.0046094,0.888106 beta-lactamase_0_S233S,beta-lactamase_0_233,TEM-1,beta-lactamase_0,P62593,,YES,233,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.886,-1.886,,,0.016,E,B,0.27,-1.01,3.579,,77.62,BPO,-1.17267,0.0500837,0.00311415,0.946975 beta-lactamase_0_S241S,beta-lactamase_0_241,TEM-1,beta-lactamase_0,P62593,,YES,241,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.433,-1.433,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.0500837,0.00452736,0.866745 beta-lactamase_0_S256S,beta-lactamase_0_256,TEM-1,beta-lactamase_0,P62593,,YES,256,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.621,-1.621,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.0500837,0.00710634,0.973004 beta-lactamase_0_S266S,beta-lactamase_0_266,TEM-1,beta-lactamase_0,P62593,,YES,266,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.369,-1.369,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.0500837,0.0140785,0.982896 beta-lactamase_0_S283S,beta-lactamase_0_283,TEM-1,beta-lactamase_0,P62593,,YES,283,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.638,-1.638,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.0500837,0.0429138,0.938809 beta-lactamase_0_S51S,beta-lactamase_0_51,TEM-1,beta-lactamase_0,P62593,,YES,51,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.526,-1.526,,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.0500837,0.00504821,0.938247 beta-lactamase_0_S57S,beta-lactamase_0_57,TEM-1,beta-lactamase_0,P62593,,YES,57,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.918,-1.918,,,0.352,E,B,0.27,-0.18,1.454,,72.73,APH,-2.29167,0.0500837,0.00492804,0.913151 beta-lactamase_0_S68S,beta-lactamase_0_68,TEM-1,beta-lactamase_0,P62593,,YES,68,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-0.913,-0.913,,,0.064,G,A,0.27,-1.03,1.441,,64.69,HPP,-1.37233,0.0500837,0.000800065,0.711674 beta-lactamase_0_S80S,beta-lactamase_0_80,TEM-1,beta-lactamase_0,P62593,,YES,80,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.029,-2.029,,,0.192,H,A,0.27,0.46,12.403,12.403,77.62,HPB,-1.44567,0.0500837,0.00565569,0.938262 beta-lactamase_0_S96S,beta-lactamase_0_96,TEM-1,beta-lactamase_0,P62593,,YES,96,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.27,-2.27,,,0.368,,b,0.27,0.39,2.516,,73.78,HPP,-2.019,0.0500837,0.00551835,0.974985 beta-lactamase_0_T107T,beta-lactamase_0_107,TEM-1,beta-lactamase_0,P62593,,YES,107,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.117,-1.117,,,,G,A,0.22,-0.06,3.73,,67.83,HPA,-1.265,0.0500837,0.00239347,0.834919 beta-lactamase_0_T112T,beta-lactamase_0_112,TEM-1,beta-lactamase_0,P62593,,YES,112,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.186,-2.186,,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.0500837,0.00531334,0.92881 beta-lactamase_0_T116T,beta-lactamase_0_116,TEM-1,beta-lactamase_0,P62593,,YES,116,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.28,-1.28,,,0.115,E,B,0.22,-0.12,1.356,,67.48,HPH,-1.39967,0.0500837,0.00336175,0.905991 beta-lactamase_0_T126T,beta-lactamase_0_126,TEM-1,beta-lactamase_0,P62593,,YES,126,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.122,-1.122,,,0.05,H,A,0.22,-0.05,0.705,,44.41,HPH,-1.60467,0.0500837,0.00244552,0.750851 beta-lactamase_0_T131T,beta-lactamase_0_131,TEM-1,beta-lactamase_0,P62593,,YES,131,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.328,-1.328,,,,H,A,0.22,-0.69,3.306,,67.48,PPH,-1.00867,0.0500837,0.00345886,0.948026 beta-lactamase_0_T138T,beta-lactamase_0_138,TEM-1,beta-lactamase_0,P62593,,YES,138,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.506,-2.506,,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.0500837,0.00487868,0.920632 beta-lactamase_0_T139T,beta-lactamase_0_139,TEM-1,beta-lactamase_0,P62593,,YES,139,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.901,-1.901,,,0.216,H,A,0.22,0.39,0.421,,77.62,PPH,-2.04667,0.0500837,0.00441837,0.862136 beta-lactamase_0_T147T,beta-lactamase_0_147,TEM-1,beta-lactamase_0,P62593,,YES,147,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.149,-1.149,,,0.281,H,A,0.22,-0.68,3.487,,64.34,HPH,-1.456,0.0500837,0.00226017,0.988304 beta-lactamase_0_T158T,beta-lactamase_0_158,TEM-1,beta-lactamase_0,P62593,,YES,158,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.116,-1.116,,,0.036,,B,0.22,-0.85,1.041,,69.58,HPB,-1.269,0.0500837,0.00341825,0.947245 beta-lactamase_0_T178T,beta-lactamase_0_178,TEM-1,beta-lactamase_0,P62593,,YES,178,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-0.791,-0.791,,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.0500837,0.000684366,0.880558 beta-lactamase_0_T179T,beta-lactamase_0_179,TEM-1,beta-lactamase_0,P62593,,YES,179,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.085,-1.085,,,,E,B,0.22,-1.38,0.367,,73.08,PPH,-1.557,0.0500837,0.00226045,0.93884 beta-lactamase_0_T186T,beta-lactamase_0_186,TEM-1,beta-lactamase_0,P62593,,YES,186,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.522,-2.522,,,0.396,H,A,0.22,-0.28,16.606,16.606,77.62,HPP,-1.77633,0.0500837,0.00485034,0.883434 beta-lactamase_0_T187T,beta-lactamase_0_187,TEM-1,beta-lactamase_0,P62593,,YES,187,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.401,-1.401,,,0.007,H,A,0.22,-1.19,3.259,,67.48,PPH,-1.69633,0.0500837,0.00491782,0.882899 beta-lactamase_0_T193T,beta-lactamase_0_193,TEM-1,beta-lactamase_0,P62593,,YES,193,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.914,-1.914,,,0.439,H,a,0.22,0.33,11.546,11.546,63.99,HPO,-1.52133,0.0500837,0.00482669,0.934028 beta-lactamase_0_T198T,beta-lactamase_0_198,TEM-1,beta-lactamase_0,P62593,,YES,198,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.168,-2.168,,,0.489,,B,0.22,-0.13,9.874,,73.78,HPH,-1.98767,0.0500837,0.004311,0.912747 beta-lactamase_0_T263T,beta-lactamase_0_263,TEM-1,beta-lactamase_0,P62593,,YES,263,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.031,-2.031,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.0500837,0.0110582,0.9275 beta-lactamase_0_T264T,beta-lactamase_0_264,TEM-1,beta-lactamase_0,P62593,,YES,264,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.985,-1.985,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.0500837,0.0119399,0.867498 beta-lactamase_0_T269T,beta-lactamase_0_269,TEM-1,beta-lactamase_0,P62593,,YES,269,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.156,-2.156,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.0500837,0.00950944,0.941749 beta-lactamase_0_T27T,beta-lactamase_0_27,TEM-1,beta-lactamase_0,P62593,,YES,27,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.905,-1.905,,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.0500837,0.00306559,0.86733 beta-lactamase_0_T69T,beta-lactamase_0_69,TEM-1,beta-lactamase_0,P62593,,YES,69,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-0.973,-0.973,,,,G,A,0.22,-1.24,0.505,,93.01,PPH,-1.01833,0.0500837,0.00127498,0.801836 beta-lactamase_0_V101V,beta-lactamase_0_101,TEM-1,beta-lactamase_0,P62593,,YES,101,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.295,-1.295,,,0.342,,B,0.44,0,1.61,,73.08,HHA,-1.54367,0.0500837,0.00374492,0.892988 beta-lactamase_0_V106V,beta-lactamase_0_106,TEM-1,beta-lactamase_0,P62593,,YES,106,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.218,-1.218,,,0.258,T,A,0.44,0.24,0.952,,72.73,OHP,-1.04933,0.0500837,0.00304168,0.962935 beta-lactamase_0_V117V,beta-lactamase_0_117,TEM-1,beta-lactamase_0,P62593,,YES,117,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.53,-1.53,,,,H,A,0.44,-0.34,1.16,,65.03,PHB,-1.741,0.0500837,0.00467906,0.358555 beta-lactamase_0_V157V,beta-lactamase_0_157,TEM-1,beta-lactamase_0,P62593,,YES,157,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.751,-1.751,,,0.308,S,a,0.44,-0.75,3.106,,69.58,BHP,-2.00767,0.0500837,0.00506849,1.02827 beta-lactamase_0_V214V,beta-lactamase_0_214,TEM-1,beta-lactamase_0,P62593,,YES,214,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.299,-1.299,,,0.375,S,A,0.44,-0.44,3.712,,74.48,BHH,-1.53733,0.0500837,0.00628442,1.20703 beta-lactamase_0_V259V,beta-lactamase_0_259,TEM-1,beta-lactamase_0,P62593,,YES,259,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.522,-1.522,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.0500837,0.0070773,0.898658 beta-lactamase_0_V260V,beta-lactamase_0_260,TEM-1,beta-lactamase_0,P62593,,YES,260,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.101,-1.101,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.0500837,0.00471757,0.895699 beta-lactamase_0_V29V,beta-lactamase_0_29,TEM-1,beta-lactamase_0,P62593,,YES,29,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-2.856,-2.856,,,0.733,H,A,0.44,-0.78,21.916,21.916,93.01,HHB,-2.24733,0.0500837,0.00318969,0.98234 beta-lactamase_0_V31V,beta-lactamase_0_31,TEM-1,beta-lactamase_0,P62593,,YES,31,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.822,-1.822,,,,H,A,0.44,-0.46,4.126,,73.78,BHB,-2.03767,0.0500837,0.00478065,0.846747 beta-lactamase_0_V42V,beta-lactamase_0_42,TEM-1,beta-lactamase_0,P62593,,YES,42,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.564,-1.564,,,0.017,E,B,0.44,-0.51,1.659,,63.99,BHO,-1.042,0.0500837,0.00404515,0.804232 beta-lactamase_0_V72V,beta-lactamase_0_72,TEM-1,beta-lactamase_0,P62593,,YES,72,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.658,-1.658,,,,H,A,0.44,-1.03,2.964,,65.73,BHH,-1.32167,0.0500837,0.00501194,0.896 beta-lactamase_0_V78V,beta-lactamase_0_78,TEM-1,beta-lactamase_0,P62593,,YES,78,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.459,-1.459,,,,H,A,0.44,-0.47,16.615,16.615,63.64,HHH,-1.17833,0.0500837,0.00492501,0.899596 beta-lactamase_0_V82V,beta-lactamase_0_82,TEM-1,beta-lactamase_0,P62593,,YES,82,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.325,-1.325,,,0.267,H,A,0.44,0.08,1.893,,93.01,BHA,-1.28567,0.0500837,0.00397046,0.858887 beta-lactamase_0_W163W,beta-lactamase_0_163,TEM-1,beta-lactamase_0,P62593,,YES,163,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-1.843,-1.843,,,0.467,,B,0.47,-0.5,13.843,13.843,63.99,BHA,-1.269,0.0500837,0.00418955,0.936922 beta-lactamase_0_W208W,beta-lactamase_0_208,TEM-1,beta-lactamase_0,P62593,,YES,208,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-0.818,-0.818,,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.0500837,0.00126609,0.799979 beta-lactamase_0_W227W,beta-lactamase_0_227,TEM-1,beta-lactamase_0,P62593,,YES,227,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-0.982,-0.982,,,0.272,,B,0.47,-0.29,3.782,,74.48,OHH,-1.595,0.0500837,0.00226019,0.801632 beta-lactamase_0_W288W,beta-lactamase_0_288,TEM-1,beta-lactamase_0,P62593,,YES,288,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,,,,,,,,,,,,,BHO,,0.0500837,,0.827441 beta-lactamase_0_Y103Y,beta-lactamase_0_103,TEM-1,beta-lactamase_0,P62593,,YES,103,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-1.33,-1.33,,,0.613,S,l,0.21,1.21,1.646,,63.29,AHP,-1.48767,0.0500837,0.00443048,0.884078 beta-lactamase_0_Y262Y,beta-lactamase_0_262,TEM-1,beta-lactamase_0,P62593,,YES,262,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-1.332,-1.332,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.0500837,0.00853516,0.872793 beta-lactamase_0_Y44Y,beta-lactamase_0_44,TEM-1,beta-lactamase_0,P62593,,YES,44,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-2.547,-2.547,,,,E,B,0.21,-0.45,1.751,,73.78,OHH,-1.86267,0.0500837,0.00426364,0.912757 beta-lactamase_0_Y95Y,beta-lactamase_0_95,TEM-1,beta-lactamase_0,P62593,,YES,95,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-1.715,-1.715,,,0.122,,b,0.21,-0.37,2.914,,77.62,BHP,-2.16167,0.0500837,0.00479449,0.804105 beta-lactamase_156_A123A,beta-lactamase_156_123,TEM-1,beta-lactamase_156,P62593,,YES,123,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.834,-0.834,,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.111618,0.0010157,0.762484 beta-lactamase_156_A124A,beta-lactamase_156_124,TEM-1,beta-lactamase_156,P62593,,YES,124,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.181,-1.181,,,,H,A,0.46,-0.9,2.027,,64.34,HHH,-1.152,0.111618,0.00481399,0.815551 beta-lactamase_156_A132A,beta-lactamase_156_132,TEM-1,beta-lactamase_156,P62593,,YES,132,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.9,-0.9,,,,H,A,0.46,-0.93,10.621,,64.69,PHH,-1.138,0.111618,0.000962524,0.708241 beta-lactamase_156_A133A,beta-lactamase_156_133,TEM-1,beta-lactamase_156,P62593,,YES,133,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.186,-1.186,,,,H,A,0.46,-0.86,0.805,,67.83,HHP,-0.988333,0.111618,0.00468022,0.802485 beta-lactamase_156_A148A,beta-lactamase_156_148,TEM-1,beta-lactamase_156,P62593,,YES,148,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.757,-1.757,,,0.379,H,A,0.46,-0.55,3.551,,72.73,PHH,-1.40167,0.111618,0.00547053,0.906853 beta-lactamase_156_A170A,beta-lactamase_156_170,TEM-1,beta-lactamase_156,P62593,,YES,170,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.237,-1.237,,,0.126,,L,0.46,-0.35,3.7,,64.69,AHH,-1.63267,0.111618,0.00431903,0.861586 beta-lactamase_156_A182A,beta-lactamase_156_182,TEM-1,beta-lactamase_156,P62593,,YES,182,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.777,-1.777,,,0.136,H,A,0.46,-0.66,16.784,16.784,93.01,OHH,-1.27367,0.111618,0.00559099,0.901851 beta-lactamase_156_A183A,beta-lactamase_156_183,TEM-1,beta-lactamase_156,P62593,,YES,183,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.231,-1.231,,,0.155,H,A,0.46,-0.91,23.859,23.859,77.62,HHH,-1.53367,0.111618,0.00296631,0.899174 beta-lactamase_156_A185A,beta-lactamase_156_185,TEM-1,beta-lactamase_156,P62593,,YES,185,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.406,-1.406,,,,H,A,0.46,-1.02,0.365,,65.03,HHP,-1.84033,0.111618,0.00467449,0.77047 beta-lactamase_156_A200A,beta-lactamase_156_200,TEM-1,beta-lactamase_156,P62593,,YES,200,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.878,-1.878,,,0.757,H,A,0.46,-0.19,16.368,16.368,77.62,HHP,-2.001,0.111618,0.0060056,0.903121 beta-lactamase_156_A211A,beta-lactamase_156_211,TEM-1,beta-lactamase_156,P62593,,YES,211,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.896,-1.896,,,0.369,T,A,0.46,-0.69,8.527,8.527,77.62,AHA,-1.94633,0.111618,0.00648183,0.91175 beta-lactamase_156_A215A,beta-lactamase_156_215,TEM-1,beta-lactamase_156,P62593,,YES,215,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.503,-1.503,,,,,a,0.46,-0.93,3.583,,74.48,HHO,-1.42633,0.111618,0.00544007,0.838874 beta-lactamase_156_A222A,beta-lactamase_156_222,TEM-1,beta-lactamase_156,P62593,,YES,222,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.103,-2.103,,,0.233,H,A,0.46,-0.25,2.461,,77.62,PHH,-1.63733,0.111618,0.00466094,0.899294 beta-lactamase_156_A225A,beta-lactamase_156_225,TEM-1,beta-lactamase_156,P62593,,YES,225,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.845,-1.845,,,1,T,B,0.46,-0.38,11.722,11.722,74.48,OHO,-1.39967,0.111618,0.00465057,0.887918 beta-lactamase_156_A230A,beta-lactamase_156_230,TEM-1,beta-lactamase_156,P62593,,YES,230,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.154,-1.154,,,0.01,E,B,0.46,-1.17,2.179,,50,HHA,-1.079,0.111618,0.00516841,0.772636 beta-lactamase_156_A235A,beta-lactamase_156_235,TEM-1,beta-lactamase_156,P62593,,YES,235,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.266,-1.266,,,0.32,E,B,0.46,-0.86,1.344,,50,OHO,-0.89,0.111618,0.00493474,0.832783 beta-lactamase_156_A246A,beta-lactamase_156_246,TEM-1,beta-lactamase_156,P62593,,YES,246,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.121,-2.121,,,0.01,E,B,0.46,-1.01,1.959,,73.78,HHH,-1.55633,0.111618,0.00569458,0.746035 beta-lactamase_156_A247A,beta-lactamase_156_247,TEM-1,beta-lactamase_156,P62593,,YES,247,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.48,-1.48,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.111618,0.00611275,0.777174 beta-lactamase_156_A268A,beta-lactamase_156_268,TEM-1,beta-lactamase_156,P62593,,YES,268,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.023,-2.023,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.111618,0.0102525,0.905764 beta-lactamase_156_A278A,beta-lactamase_156_278,TEM-1,beta-lactamase_156,P62593,,YES,278,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.348,-1.348,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.111618,0.0310297,0.790591 beta-lactamase_156_A282A,beta-lactamase_156_282,TEM-1,beta-lactamase_156,P62593,,YES,282,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.586,-1.586,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.111618,0.0449821,0.807135 beta-lactamase_156_A34A,beta-lactamase_156_34,TEM-1,beta-lactamase_156,P62593,,YES,34,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.059,-2.059,,,,H,A,0.46,-0.54,3.614,,73.78,AHA,-1.74967,0.111618,0.00407913,0.795401 beta-lactamase_156_A40A,beta-lactamase_156_40,TEM-1,beta-lactamase_156,P62593,,YES,40,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.402,-1.402,,,0.155,S,B,0.46,0.21,1.357,,73.78,OHB,-1.40267,0.111618,0.00490026,0.861783 beta-lactamase_156_A77A,beta-lactamase_156_77,TEM-1,beta-lactamase_156,P62593,,YES,77,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.234,-1.234,,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.111618,0.00282362,0.807933 beta-lactamase_156_A84A,beta-lactamase_156_84,TEM-1,beta-lactamase_156,P62593,,YES,84,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.651,-1.651,,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.111618,0.00503822,0.898868 beta-lactamase_156_C121C,beta-lactamase_156_121,TEM-1,beta-lactamase_156,P62593,,YES,121,C,C,CC,Special,Special,5.07,5.07,0,0,121,121,0,108.5,108.5,0,-0.953,-0.953,,,,H,A,0.46,-0.81,1.136,,63.29,HOP,-1.46767,0.111618,0.000744322,0.773728 beta-lactamase_156_C75C,beta-lactamase_156_75,TEM-1,beta-lactamase_156,P62593,,YES,75,C,C,CC,Special,Special,5.07,5.07,0,0,121,121,0,108.5,108.5,0,-1.245,-1.245,,,,H,A,0.46,-0.87,0.876,,50,HOO,-1.24333,0.111618,0.0034616,0.823546 beta-lactamase_156_D113D,beta-lactamase_156_113,TEM-1,beta-lactamase_156,P62593,,YES,113,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.829,-1.829,,,0.665,T,A,0.75,0.91,2.973,,73.08,PAO,-1.703,0.111618,0.00474112,0.888923 beta-lactamase_156_D129D,beta-lactamase_156_129,TEM-1,beta-lactamase_156,P62593,,YES,129,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.816,-0.816,,,,,B,0.75,-0.69,1.924,,34.97,PAP,-0.818,0.111618,0.00109178,0.517194 beta-lactamase_156_D155D,beta-lactamase_156_155,TEM-1,beta-lactamase_156,P62593,,YES,155,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.889,-0.889,,,0.049,,B,0.75,-0.9,0.315,,64.69,OAB,-1.62267,0.111618,0.00135315,0.609372 beta-lactamase_156_D161D,beta-lactamase_156_161,TEM-1,beta-lactamase_156,P62593,,YES,161,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.891,-0.891,,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.111618,0.000897697,0.842958 beta-lactamase_156_D174D,beta-lactamase_156_174,TEM-1,beta-lactamase_156,P62593,,YES,174,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.738,-0.738,,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.111618,0.00125633,0.848627 beta-lactamase_156_D177D,beta-lactamase_156_177,TEM-1,beta-lactamase_156,P62593,,YES,177,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.967,-0.967,,,0.006,T,L,0.75,-1.02,2.072,,64.69,BAP,-0.873667,0.111618,0.000864022,0.543387 beta-lactamase_156_D207D,beta-lactamase_156_207,TEM-1,beta-lactamase_156,P62593,,YES,207,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.064,-2.064,,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.111618,0.00592942,0.873223 beta-lactamase_156_D212D,beta-lactamase_156_212,TEM-1,beta-lactamase_156,P62593,,YES,212,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.624,-1.624,,,0.037,,b,0.75,-0.58,20.222,20.222,74.48,HAB,-1.77667,0.111618,0.00644302,0.838986 beta-lactamase_156_D231D,beta-lactamase_156_231,TEM-1,beta-lactamase_156,P62593,,YES,231,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.816,-0.816,,,,E,B,0.75,-1.06,2.66,,65.38,HAB,-0.994,0.111618,0.00107395,0.630341 beta-lactamase_156_D252D,beta-lactamase_156_252,TEM-1,beta-lactamase_156,P62593,,YES,252,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.94,-1.94,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.111618,0.00575769,0.900345 beta-lactamase_156_D271D,beta-lactamase_156_271,TEM-1,beta-lactamase_156,P62593,,YES,271,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.249,-1.249,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.111618,0.00752082,0.790081 beta-lactamase_156_D33D,beta-lactamase_156_33,TEM-1,beta-lactamase_156,P62593,,YES,33,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.321,-2.321,,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.111618,0.00435556,0.880524 beta-lactamase_156_D36D,beta-lactamase_156_36,TEM-1,beta-lactamase_156,P62593,,YES,36,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.732,-2.732,,,0.555,H,A,0.75,1.17,14.871,14.871,77.62,AAP,-1.91167,0.111618,0.00476483,0.888803 beta-lactamase_156_D48D,beta-lactamase_156_48,TEM-1,beta-lactamase_156,P62593,,YES,48,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.101,-1.101,,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.111618,0.0027273,0.808442 beta-lactamase_156_D83D,beta-lactamase_156_83,TEM-1,beta-lactamase_156,P62593,,YES,83,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.066,-1.066,,,0.354,H,A,0.75,0.22,1.281,,48.95,HAH,-1.34733,0.111618,0.00205968,0.807205 beta-lactamase_156_D99D,beta-lactamase_156_99,TEM-1,beta-lactamase_156,P62593,,YES,99,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.191,-1.191,,,0.402,G,A,0.75,0.36,3.529,,64.69,PAH,-1.794,0.111618,0.00305446,0.889652 beta-lactamase_156_E102E,beta-lactamase_156_102,TEM-1,beta-lactamase_156,P62593,,YES,102,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.118,-2.118,,,0.722,S,B,1.04,1.82,15.721,15.721,73.08,HAH,-1.581,0.111618,0.00486633,0.90155 beta-lactamase_156_E108E,beta-lactamase_156_108,TEM-1,beta-lactamase_156,P62593,,YES,108,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.46,-1.46,,,0.572,G,A,1.04,1.87,8.602,8.602,72.73,PAB,-1.437,0.111618,0.00413372,0.900267 beta-lactamase_156_E119E,beta-lactamase_156_119,TEM-1,beta-lactamase_156,P62593,,YES,119,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.412,-1.412,,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.111618,0.00386966,0.855108 beta-lactamase_156_E145E,beta-lactamase_156_145,TEM-1,beta-lactamase_156,P62593,,YES,145,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.357,-2.357,,,0.545,H,A,1.04,0.79,3.661,,77.62,BAH,-2.069,0.111618,0.00553285,0.908928 beta-lactamase_156_E164E,beta-lactamase_156_164,TEM-1,beta-lactamase_156,P62593,,YES,164,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-0.948,-0.948,,,0.011,T,B,1.04,-0.4,3.445,,64.69,HAO,-1.388,0.111618,0.00137286,0.548482 beta-lactamase_156_E166E,beta-lactamase_156_166,TEM-1,beta-lactamase_156,P62593,,YES,166,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.756,-1.756,,,0.508,G,A,1.04,1.05,2.393,,73.08,OAH,-1.42233,0.111618,0.00512989,0.903547 beta-lactamase_156_E169E,beta-lactamase_156_169,TEM-1,beta-lactamase_156,P62593,,YES,169,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.23,-1.23,,,0.337,,A,1.04,1,3.516,,73.08,PAH,-1.16533,0.111618,0.00400994,0.876263 beta-lactamase_156_E175E,beta-lactamase_156_175,TEM-1,beta-lactamase_156,P62593,,YES,175,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.336,-2.336,,,0.551,,A,1.04,1.05,2.334,,77.62,AAB,-1.31233,0.111618,0.00482205,0.896465 beta-lactamase_156_E195E,beta-lactamase_156_195,TEM-1,beta-lactamase_156,P62593,,YES,195,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.186,-2.186,,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.111618,0.00496565,0.880887 beta-lactamase_156_E210E,beta-lactamase_156_210,TEM-1,beta-lactamase_156,P62593,,YES,210,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.319,-2.319,,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.111618,0.00663582,0.901752 beta-lactamase_156_E238E,beta-lactamase_156_238,TEM-1,beta-lactamase_156,P62593,,YES,238,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.002,-2.002,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.111618,0.00743256,0.891444 beta-lactamase_156_E26E,beta-lactamase_156_26,TEM-1,beta-lactamase_156,P62593,,YES,26,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.454,-2.454,,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.111618,0.00297948,0.898379 beta-lactamase_156_E272E,beta-lactamase_156_272,TEM-1,beta-lactamase_156,P62593,,YES,272,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.127,-1.127,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.111618,0.00545371,0.716057 beta-lactamase_156_E279E,beta-lactamase_156_279,TEM-1,beta-lactamase_156,P62593,,YES,279,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.038,-1.038,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.111618,0.0192826,0.675978 beta-lactamase_156_E35E,beta-lactamase_156_35,TEM-1,beta-lactamase_156,P62593,,YES,35,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-0.869,-0.869,,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.111618,0.00174441,0.817963 beta-lactamase_156_E46E,beta-lactamase_156_46,TEM-1,beta-lactamase_156,P62593,,YES,46,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.94,-1.94,,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.111618,0.00427568,0.788451 beta-lactamase_156_E56E,beta-lactamase_156_56,TEM-1,beta-lactamase_156,P62593,,YES,56,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.043,-2.043,,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.111618,0.00238534,0.860611 beta-lactamase_156_E61E,beta-lactamase_156_61,TEM-1,beta-lactamase_156,P62593,,YES,61,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.115,-2.115,,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.111618,0.00440955,0.886805 beta-lactamase_156_E62E,beta-lactamase_156_62,TEM-1,beta-lactamase_156,P62593,,YES,62,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.193,-1.193,,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.111618,0.00264802,0.865727 beta-lactamase_156_E87E,beta-lactamase_156_87,TEM-1,beta-lactamase_156,P62593,,YES,87,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.421,-1.421,,,0.048,,B,1.04,0.92,1.754,,64.69,PAP,-1.969,0.111618,0.00337888,0.795817 beta-lactamase_156_F149F,beta-lactamase_156_149,TEM-1,beta-lactamase_156,P62593,,YES,149,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.299,-1.299,,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.111618,0.00418462,0.886692 beta-lactamase_156_F228F,beta-lactamase_156_228,TEM-1,beta-lactamase_156,P62593,,YES,228,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-2.342,-2.342,,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.111618,0.0046669,0.873069 beta-lactamase_156_F58F,beta-lactamase_156_58,TEM-1,beta-lactamase_156,P62593,,YES,58,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-2.914,-2.914,,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.111618,0.00523369,0.877232 beta-lactamase_156_F64F,beta-lactamase_156_64,TEM-1,beta-lactamase_156,P62593,,YES,64,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-0.841,-0.841,,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.111618,0.000947691,0.61769 beta-lactamase_156_F70F,beta-lactamase_156_70,TEM-1,beta-lactamase_156,P62593,,YES,70,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.169,-1.169,,,,H,A,0.58,-1.34,1.918,,63.99,PHB,-0.980667,0.111618,0.00193499,0.765639 beta-lactamase_156_G114G,beta-lactamase_156_114,TEM-1,beta-lactamase_156,P62593,,YES,114,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.094,-1.094,,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.111618,0.00224919,0.793921 beta-lactamase_156_G141G,beta-lactamase_156_141,TEM-1,beta-lactamase_156,P62593,,YES,141,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.828,-0.828,,,0.575,T,l,0.29,-0.28,0.198,,64.69,HOO,-1.08933,0.111618,0.0012419,0.854685 beta-lactamase_156_G142G,beta-lactamase_156_142,TEM-1,beta-lactamase_156,P62593,,YES,142,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.707,-0.707,,,0.034,,p,0.29,-0.64,0.325,,64.69,OOO,-0.834,0.111618,0.00060149,0.808689 beta-lactamase_156_G154G,beta-lactamase_156_154,TEM-1,beta-lactamase_156,P62593,,YES,154,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.823,-0.823,,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.111618,0.00180205,0.865983 beta-lactamase_156_G194G,beta-lactamase_156_194,TEM-1,beta-lactamase_156,P62593,,YES,194,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.396,-1.396,,,0.276,S,b,0.29,0.36,1.346,,67.83,POA,-1.832,0.111618,0.00392163,0.87813 beta-lactamase_156_G216G,beta-lactamase_156_216,TEM-1,beta-lactamase_156,P62593,,YES,216,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.477,-1.477,,,0.437,I,A,0.29,-0.58,12.464,12.464,74.48,HOO,-1.68067,0.111618,0.00639568,0.906597 beta-lactamase_156_G226G,beta-lactamase_156_226,TEM-1,beta-lactamase_156,P62593,,YES,226,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.461,-1.461,,,0.701,T,l,0.29,-0.25,3.199,,74.48,HOH,-1.42933,0.111618,0.00665294,0.903863 beta-lactamase_156_G234G,beta-lactamase_156_234,TEM-1,beta-lactamase_156,P62593,,YES,234,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.62,-0.62,,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.111618,0.000889577,0.760758 beta-lactamase_156_G236G,beta-lactamase_156_236,TEM-1,beta-lactamase_156,P62593,,YES,236,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.784,-0.784,,,0.241,,b,0.29,-0.59,1.883,,64.69,HOO,-1.025,0.111618,0.00162372,0.819581 beta-lactamase_156_G240G,beta-lactamase_156_240,TEM-1,beta-lactamase_156,P62593,,YES,240,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.537,-1.537,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.111618,0.00591201,0.799886 beta-lactamase_156_G243G,beta-lactamase_156_243,TEM-1,beta-lactamase_156,P62593,,YES,243,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.532,-1.532,,,,E,B,0.77,-1.24,2.866,,50,BOH,-1.46867,0.111618,0.00464034,0.743468 beta-lactamase_156_G249G,beta-lactamase_156_249,TEM-1,beta-lactamase_156,P62593,,YES,249,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.312,-1.312,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.111618,0.00220169,0.883717 beta-lactamase_156_G253G,beta-lactamase_156_253,TEM-1,beta-lactamase_156,P62593,,YES,253,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-2.253,-2.253,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.111618,0.00786358,0.884821 beta-lactamase_156_G265G,beta-lactamase_156_265,TEM-1,beta-lactamase_156,P62593,,YES,265,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-2.58,-2.58,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.111618,0.00811926,0.9112 beta-lactamase_156_G281G,beta-lactamase_156_281,TEM-1,beta-lactamase_156,P62593,,YES,281,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-2.247,-2.247,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.111618,0.0406482,0.888008 beta-lactamase_156_G39G,beta-lactamase_156_39,TEM-1,beta-lactamase_156,P62593,,YES,39,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.864,-1.864,,,0.701,T,L,0.29,0.47,1.454,,77.62,HOH,-1.53633,0.111618,0.00487611,0.886025 beta-lactamase_156_G43G,beta-lactamase_156_43,TEM-1,beta-lactamase_156,P62593,,YES,43,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.62,-0.62,,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.111618,0.00120151,0.722519 beta-lactamase_156_G52G,beta-lactamase_156_52,TEM-1,beta-lactamase_156,P62593,,YES,52,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.149,-1.149,,,0.299,,l,0.29,-0.04,1.179,,64.69,POB,-1.66267,0.111618,0.00340138,0.867952 beta-lactamase_156_G76G,beta-lactamase_156_76,TEM-1,beta-lactamase_156,P62593,,YES,76,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.189,-1.189,,,,H,A,0.29,-0.67,3.059,,67.83,OOH,-1.22267,0.111618,0.00476637,0.789578 beta-lactamase_156_G85G,beta-lactamase_156_85,TEM-1,beta-lactamase_156,P62593,,YES,85,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.011,-1.011,,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.111618,0.00252173,0.863661 beta-lactamase_156_G90G,beta-lactamase_156_90,TEM-1,beta-lactamase_156,P62593,,YES,90,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-2.091,-2.091,,,0.598,T,A,0.29,0.32,0.319,,77.62,HOB,-1.52633,0.111618,0.00490273,0.888944 beta-lactamase_156_H110H,beta-lactamase_156_110,TEM-1,beta-lactamase_156,P62593,,YES,110,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-1.706,-1.706,,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.111618,0.00441499,0.910283 beta-lactamase_156_H151H,beta-lactamase_156_151,TEM-1,beta-lactamase_156,P62593,,YES,151,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-2.96,-2.96,,,0.594,H,A,0.17,0.1,1.401,,77.62,HBP,-2.34767,0.111618,0.00216946,0.887572 beta-lactamase_156_H156H,beta-lactamase_156_156,TEM-1,beta-lactamase_156,P62593,,YES,156,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-3.156,-3.156,,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.111618,0.00468596,0.903343 beta-lactamase_156_H24H,beta-lactamase_156_24,TEM-1,beta-lactamase_156,P62593,,YES,24,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-2.481,-2.481,,,,,,,,2.708,,93.01,OBO,-2.0035,0.111618,0.00238894,0.821551 beta-lactamase_156_H287H,beta-lactamase_156_287,TEM-1,beta-lactamase_156,P62593,,YES,287,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,,,,,,,,,,,,,BBH,-1.111,0.111618,,0.834343 beta-lactamase_156_H94H,beta-lactamase_156_94,TEM-1,beta-lactamase_156,P62593,,YES,94,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-2.5,-2.5,,,0.776,,B,0.17,1.24,11.583,11.583,77.62,HBH,-1.872,0.111618,0.00389226,0.894015 beta-lactamase_156_I125I,beta-lactamase_156_125,TEM-1,beta-lactamase_156,P62593,,YES,125,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.441,-1.441,,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.111618,0.00383964,0.761701 beta-lactamase_156_I140I,beta-lactamase_156_140,TEM-1,beta-lactamase_156,P62593,,YES,140,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.733,-1.733,,,0.128,H,A,0.48,0.41,1.16,,73.08,PHO,-1.48733,0.111618,0.00597777,0.88256 beta-lactamase_156_I171I,beta-lactamase_156_171,TEM-1,beta-lactamase_156,P62593,,YES,171,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-2.431,-2.431,,,0.361,,B,0.48,0.53,3.869,,77.62,HHO,-1.55533,0.111618,0.00623355,0.902479 beta-lactamase_156_I206I,beta-lactamase_156_206,TEM-1,beta-lactamase_156,P62593,,YES,206,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-2.429,-2.429,,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.111618,0.00528934,0.891733 beta-lactamase_156_I229I,beta-lactamase_156_229,TEM-1,beta-lactamase_156,P62593,,YES,229,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.267,-1.267,,,0.083,E,B,0.48,-0.76,1.114,,50,HHH,-1.58767,0.111618,0.00477249,0.757331 beta-lactamase_156_I244I,beta-lactamase_156_244,TEM-1,beta-lactamase_156,P62593,,YES,244,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.555,-1.555,,,,E,B,0.48,-0.84,1.325,,77.62,OHH,-1.385,0.111618,0.00605379,0.761656 beta-lactamase_156_I245I,beta-lactamase_156_245,TEM-1,beta-lactamase_156,P62593,,YES,245,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.068,-1.068,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.111618,0.00391032,0.757983 beta-lactamase_156_I258I,beta-lactamase_156_258,TEM-1,beta-lactamase_156,P62593,,YES,258,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.975,-1.975,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.111618,0.007931,0.753217 beta-lactamase_156_I261I,beta-lactamase_156_261,TEM-1,beta-lactamase_156,P62593,,YES,261,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-2.88,-2.88,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.111618,0.0123091,0.750813 beta-lactamase_156_I277I,beta-lactamase_156_277,TEM-1,beta-lactamase_156,P62593,,YES,277,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.869,-1.869,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.111618,0.0169305,0.897222 beta-lactamase_156_I280I,beta-lactamase_156_280,TEM-1,beta-lactamase_156,P62593,,YES,280,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.708,-1.708,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.111618,0.0530888,0.876853 beta-lactamase_156_I285I,beta-lactamase_156_285,TEM-1,beta-lactamase_156,P62593,,YES,285,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.845,-1.845,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.111618,0.101555,0.901136 beta-lactamase_156_I45I,beta-lactamase_156_45,TEM-1,beta-lactamase_156,P62593,,YES,45,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-2.421,-2.421,,,,E,B,0.48,-0.3,2.256,,77.62,HHA,-2.30267,0.111618,0.00452842,0.755328 beta-lactamase_156_I54I,beta-lactamase_156_54,TEM-1,beta-lactamase_156,P62593,,YES,54,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-2.838,-2.838,,,0.669,E,B,0.48,-0.14,0.541,,73.78,BHH,-2.337,0.111618,0.00403589,0.891305 beta-lactamase_156_I93I,beta-lactamase_156_93,TEM-1,beta-lactamase_156,P62593,,YES,93,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.401,-1.401,,,0.128,E,B,0.48,0.44,1.524,,67.83,BHB,-1.873,0.111618,0.00527066,0.863541 beta-lactamase_156_K109K,beta-lactamase_156_109,TEM-1,beta-lactamase_156,P62593,,YES,109,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.734,-1.734,,,0.787,G,A,2.34,2.21,6.031,,72.73,ABB,-1.63333,0.111618,0.00462493,0.906075 beta-lactamase_156_K144K,beta-lactamase_156_144,TEM-1,beta-lactamase_156,P62593,,YES,144,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-2.388,-2.388,,,0.863,H,A,2.34,1.27,2.073,,77.62,OBA,-1.904,0.111618,0.00481141,0.884229 beta-lactamase_156_K190K,beta-lactamase_156_190,TEM-1,beta-lactamase_156,P62593,,YES,190,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.994,-1.994,,,0.371,H,A,2.34,0.16,1.513,,77.62,BBH,-1.64167,0.111618,0.00574527,0.894735 beta-lactamase_156_K213K,beta-lactamase_156_213,TEM-1,beta-lactamase_156,P62593,,YES,213,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.81,-1.81,,,0.67,,A,2.34,0.29,3.924,,67.83,ABH,-1.57767,0.111618,0.00610411,0.904732 beta-lactamase_156_K232K,beta-lactamase_156_232,TEM-1,beta-lactamase_156,P62593,,YES,232,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.012,-1.012,,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.111618,0.00313441,0.465462 beta-lactamase_156_K254K,beta-lactamase_156_254,TEM-1,beta-lactamase_156,P62593,,YES,254,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-2.126,-2.126,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.111618,0.00369,0.862737 beta-lactamase_156_K286K,beta-lactamase_156_286,TEM-1,beta-lactamase_156,P62593,,YES,286,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.111,-1.111,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.111618,,0.854387 beta-lactamase_156_K30K,beta-lactamase_156_30,TEM-1,beta-lactamase_156,P62593,,YES,30,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-2.307,-2.307,,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.111618,0.00448593,0.875033 beta-lactamase_156_K32K,beta-lactamase_156_32,TEM-1,beta-lactamase_156,P62593,,YES,32,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.984,-1.984,,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.111618,0.00401283,0.886566 beta-lactamase_156_K53K,beta-lactamase_156_53,TEM-1,beta-lactamase_156,P62593,,YES,53,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-2.313,-2.313,,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.111618,0.00383383,0.888299 beta-lactamase_156_K71K,beta-lactamase_156_71,TEM-1,beta-lactamase_156,P62593,,YES,71,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-0.8,-0.8,,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.111618,0.00103192,0.44684 beta-lactamase_156_L100L,beta-lactamase_156_100,TEM-1,beta-lactamase_156,P62593,,YES,100,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.218,-1.218,,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.111618,0.00413885,0.87535 beta-lactamase_156_L111L,beta-lactamase_156_111,TEM-1,beta-lactamase_156,P62593,,YES,111,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.76,-1.76,,,0.328,T,A,0.55,0.93,2.26,,64.34,BHP,-1.884,0.111618,0.00480671,0.888061 beta-lactamase_156_L120L,beta-lactamase_156_120,TEM-1,beta-lactamase_156,P62593,,YES,120,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.044,-1.044,,,,H,A,0.55,-1.13,7.813,,64.69,AHO,-1.13633,0.111618,0.00143563,0.796463 beta-lactamase_156_L135L,beta-lactamase_156_135,TEM-1,beta-lactamase_156,P62593,,YES,135,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.002,-1.002,,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.111618,0.00244423,0.818058 beta-lactamase_156_L136L,beta-lactamase_156_136,TEM-1,beta-lactamase_156,P62593,,YES,136,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.232,-1.232,,,,H,A,0.55,-0.34,1.04,,48.95,HHH,-1.088,0.111618,0.00442304,0.762236 beta-lactamase_156_L137L,beta-lactamase_156_137,TEM-1,beta-lactamase_156,P62593,,YES,137,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.03,-1.03,,,,H,A,0.55,-0.38,0.674,,42.31,HHP,-1.58933,0.111618,0.00278599,0.764838 beta-lactamase_156_L146L,beta-lactamase_156_146,TEM-1,beta-lactamase_156,P62593,,YES,146,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.462,-1.462,,,0.007,H,A,0.55,-0.56,1.578,,64.69,AHP,-1.656,0.111618,0.00474542,0.790558 beta-lactamase_156_L150L,beta-lactamase_156_150,TEM-1,beta-lactamase_156,P62593,,YES,150,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.326,-1.326,,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.111618,0.00463171,0.79099 beta-lactamase_156_L160L,beta-lactamase_156_160,TEM-1,beta-lactamase_156,P62593,,YES,160,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.977,-0.977,,,0.022,,B,0.55,-0.6,1.095,,44.41,BHA,-0.936,0.111618,0.00193775,0.750863 beta-lactamase_156_L167L,beta-lactamase_156_167,TEM-1,beta-lactamase_156,P62593,,YES,167,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.138,-1.138,,,0.015,G,A,0.55,-0.63,0.4,,64.69,AHP,-1.30767,0.111618,0.00303566,0.759903 beta-lactamase_156_L188L,beta-lactamase_156_188,TEM-1,beta-lactamase_156,P62593,,YES,188,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.166,-1.166,,,,H,A,0.55,-0.3,1.574,,60.14,PHB,-1.47033,0.111618,0.00295687,0.759326 beta-lactamase_156_L191L,beta-lactamase_156_191,TEM-1,beta-lactamase_156,P62593,,YES,191,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.087,-1.087,,,,H,A,0.55,0.09,1.372,,63.29,BHH,-1.445,0.111618,0.00263549,0.761222 beta-lactamase_156_L192L,beta-lactamase_156_192,TEM-1,beta-lactamase_156,P62593,,YES,192,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.254,-1.254,,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.111618,0.00558728,0.815624 beta-lactamase_156_L196L,beta-lactamase_156_196,TEM-1,beta-lactamase_156,P62593,,YES,196,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-2.478,-2.478,,,0.518,S,A,0.55,1.35,7.897,,77.62,AHH,-1.839,0.111618,0.00512144,0.915007 beta-lactamase_156_L197L,beta-lactamase_156_197,TEM-1,beta-lactamase_156,P62593,,YES,197,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.853,-0.853,,,0.007,S,B,0.55,0.33,1.58,,60.14,HHP,-1.833,0.111618,0.00144602,0.745305 beta-lactamase_156_L199L,beta-lactamase_156_199,TEM-1,beta-lactamase_156,P62593,,YES,199,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-2.942,-2.942,,,0.832,H,A,0.55,0.42,1.552,,77.62,PHH,-2.32933,0.111618,0.0048649,0.90681 beta-lactamase_156_L205L,beta-lactamase_156_205,TEM-1,beta-lactamase_156,P62593,,YES,205,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.922,-0.922,,,,H,A,0.55,-0.46,0.678,,42.31,PHH,-1.57767,0.111618,0.00255802,0.742897 beta-lactamase_156_L218L,beta-lactamase_156_218,TEM-1,beta-lactamase_156,P62593,,YES,218,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.391,-1.391,,,,I,b,0.55,-0.53,17.202,17.202,74.48,OHH,-1.58867,0.111618,0.00618274,0.802066 beta-lactamase_156_L219L,beta-lactamase_156_219,TEM-1,beta-lactamase_156,P62593,,YES,219,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.313,-1.313,,,,I,A,0.55,-0.51,2.321,,74.48,HHB,-1.21533,0.111618,0.00664345,0.803188 beta-lactamase_156_L223L,beta-lactamase_156_223,TEM-1,beta-lactamase_156,P62593,,YES,223,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.055,-1.055,,,0.27,,B,0.55,0.09,1.511,,74.48,HHO,-1.35033,0.111618,0.00372793,0.838318 beta-lactamase_156_L248L,beta-lactamase_156_248,TEM-1,beta-lactamase_156,P62593,,YES,248,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.794,-1.794,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.111618,0.00428493,0.743667 beta-lactamase_156_L284L,beta-lactamase_156_284,TEM-1,beta-lactamase_156,P62593,,YES,284,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.981,-1.981,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.111618,0.0686156,0.897323 beta-lactamase_156_L28L,beta-lactamase_156_28,TEM-1,beta-lactamase_156,P62593,,YES,28,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.579,-1.579,,,0.277,H,A,0.55,-0.16,3.262,,93.01,PHH,-2.11333,0.111618,0.00359321,0.887346 beta-lactamase_156_L38L,beta-lactamase_156_38,TEM-1,beta-lactamase_156,P62593,,YES,38,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.343,-1.343,,,0.088,H,A,0.55,0.2,13.556,13.556,64.34,PHO,-1.78033,0.111618,0.00373244,0.849707 beta-lactamase_156_L47L,beta-lactamase_156_47,TEM-1,beta-lactamase_156,P62593,,YES,47,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.876,-1.876,,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.111618,0.00439844,0.785712 beta-lactamase_156_L49L,beta-lactamase_156_49,TEM-1,beta-lactamase_156,P62593,,YES,49,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.897,-1.897,,,0.131,T,A,0.55,0.04,3.112,,64.69,AHP,-1.99233,0.111618,0.00401477,0.877881 beta-lactamase_156_L55L,beta-lactamase_156_55,TEM-1,beta-lactamase_156,P62593,,YES,55,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.86,-1.86,,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.111618,0.00403741,0.890621 beta-lactamase_156_L73L,beta-lactamase_156_73,TEM-1,beta-lactamase_156,P62593,,YES,73,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.507,-1.507,,,,H,A,0.55,-0.64,2.09,,67.83,HHH,-1.487,0.111618,0.00488983,0.809625 beta-lactamase_156_L74L,beta-lactamase_156_74,TEM-1,beta-lactamase_156,P62593,,YES,74,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.296,-1.296,,,,H,A,0.55,-0.91,0.746,,50,HHO,-1.34933,0.111618,0.00493255,0.799884 beta-lactamase_156_L79L,beta-lactamase_156_79,TEM-1,beta-lactamase_156,P62593,,YES,79,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.842,-0.842,,,0.007,H,A,0.55,-0.16,1.831,,50.35,HHP,-1.44333,0.111618,0.000947397,0.756904 beta-lactamase_156_L89L,beta-lactamase_156_89,TEM-1,beta-lactamase_156,P62593,,YES,89,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.096,-1.096,,,0.168,T,A,0.55,0.63,2.633,,64.34,PHO,-1.75767,0.111618,0.00207068,0.851532 beta-lactamase_156_M115M,beta-lactamase_156_115,TEM-1,beta-lactamase_156,P62593,,YES,115,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.389,-1.389,,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.111618,0.0034337,0.767344 beta-lactamase_156_M127M,beta-lactamase_156_127,TEM-1,beta-lactamase_156,P62593,,YES,127,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-2.251,-2.251,,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.111618,0.00437927,1.06155 beta-lactamase_156_M153M,beta-lactamase_156_153,TEM-1,beta-lactamase_156,P62593,,YES,153,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-3.193,-3.193,,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.111618,0.00509109,0.942042 beta-lactamase_156_M180M,beta-lactamase_156_180,TEM-1,beta-lactamase_156,P62593,,YES,180,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-2.795,-2.795,,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.111618,0.00552048,0.952419 beta-lactamase_156_M184M,beta-lactamase_156_184,TEM-1,beta-lactamase_156,P62593,,YES,184,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.593,-1.593,,,,H,A,0.55,-0.87,1.671,,62.94,HHH,-1.41,0.111618,0.00356019,0.764159 beta-lactamase_156_M209M,beta-lactamase_156_209,TEM-1,beta-lactamase_156,P62593,,YES,209,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.442,-1.442,,,,H,A,0.55,-0.97,1.066,,64.69,HHA,-1.52633,0.111618,0.00625021,0.711035 beta-lactamase_156_M270M,beta-lactamase_156_270,TEM-1,beta-lactamase_156,P62593,,YES,270,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.723,-1.723,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.111618,0.00767762,1.01718 beta-lactamase_156_M66M,beta-lactamase_156_66,TEM-1,beta-lactamase_156,P62593,,YES,66,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.362,-1.362,,,0.013,,A,0.55,-0.7,1.94,,73.08,OHH,-1.49567,0.111618,0.00412876,0.773024 beta-lactamase_156_M67M,beta-lactamase_156_67,TEM-1,beta-lactamase_156,P62593,,YES,67,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-2.231,-2.231,,,0.006,G,P,0.55,-0.81,1.463,,65.03,HHP,-1.502,0.111618,0.00409753,0.780722 beta-lactamase_156_N130N,beta-lactamase_156_130,TEM-1,beta-lactamase_156,P62593,,YES,130,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-0.798,-0.798,,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.111618,0.000683376,0.772333 beta-lactamase_156_N134N,beta-lactamase_156_134,TEM-1,beta-lactamase_156,P62593,,YES,134,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-0.879,-0.879,,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.111618,0.000644786,0.833293 beta-lactamase_156_N152N,beta-lactamase_156_152,TEM-1,beta-lactamase_156,P62593,,YES,152,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-2.757,-2.757,,,0.863,H,A,0.61,0.92,4.038,,77.62,BPH,-2.97,0.111618,0.00471429,0.892215 beta-lactamase_156_N168N,beta-lactamase_156_168,TEM-1,beta-lactamase_156,P62593,,YES,168,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-1.029,-1.029,,,0.113,G,A,0.61,-0.4,1.014,,44.41,HPA,-1.13233,0.111618,0.00288667,0.82052 beta-lactamase_156_N173N,beta-lactamase_156_173,TEM-1,beta-lactamase_156,P62593,,YES,173,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-2.663,-2.663,,,1.044,T,l,0.61,1.25,3.718,,77.62,OPA,-1.46633,0.111618,0.0033769,0.878725 beta-lactamase_156_N274N,beta-lactamase_156_274,TEM-1,beta-lactamase_156,P62593,,YES,274,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-2.082,-2.082,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.111618,0.0110418,0.821379 beta-lactamase_156_N50N,beta-lactamase_156_50,TEM-1,beta-lactamase_156,P62593,,YES,50,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-2.979,-2.979,,,0.912,T,A,0.61,1.24,13.295,13.295,77.62,HPP,-2.134,0.111618,0.0047211,0.886711 beta-lactamase_156_N98N,beta-lactamase_156_98,TEM-1,beta-lactamase_156,P62593,,YES,98,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-2.973,-2.973,,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.111618,0.00505389,0.890494 beta-lactamase_156_P105P,beta-lactamase_156_105,TEM-1,beta-lactamase_156,P62593,,YES,105,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.813,-0.813,,,0.226,T,A,0.52,0.8,1.154,,63.29,POH,-1.01533,0.111618,0.0011981,0.51944 beta-lactamase_156_P143P,beta-lactamase_156_143,TEM-1,beta-lactamase_156,P62593,,YES,143,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.967,-0.967,,,0.075,H,A,0.52,-0.37,0.479,,66.78,OOB,-1.354,0.111618,0.00114551,0.608807 beta-lactamase_156_P165P,beta-lactamase_156_165,TEM-1,beta-lactamase_156,P62593,,YES,165,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.373,-1.373,,,0.203,T,A,0.52,-0.31,3.907,,73.78,AOA,-1.359,0.111618,0.00549538,0.679256 beta-lactamase_156_P172P,beta-lactamase_156_172,TEM-1,beta-lactamase_156,P62593,,YES,172,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.998,-0.998,,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.111618,0.00312594,0.797223 beta-lactamase_156_P181P,beta-lactamase_156_181,TEM-1,beta-lactamase_156,P62593,,YES,181,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.813,-0.813,,,,H,A,0.52,-1.14,1.078,,61.54,HOH,-1.795,0.111618,0.000703122,0.6043 beta-lactamase_156_P217P,beta-lactamase_156_217,TEM-1,beta-lactamase_156,P62593,,YES,217,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-2.062,-2.062,,,0.496,I,A,0.52,-0.33,2.303,,74.48,OOH,-1.64333,0.111618,0.00463211,0.853771 beta-lactamase_156_P224P,beta-lactamase_156_224,TEM-1,beta-lactamase_156,P62593,,YES,224,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.893,-0.893,,,0.383,,B,0.52,-0.3,0.383,,74.48,HOH,-1.26433,0.111618,0.00189564,0.758516 beta-lactamase_156_P250P,beta-lactamase_156_250,TEM-1,beta-lactamase_156,P62593,,YES,250,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-2.335,-2.335,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.111618,0.00550899,0.880378 beta-lactamase_156_P255P,beta-lactamase_156_255,TEM-1,beta-lactamase_156,P62593,,YES,255,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-2.266,-2.266,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.111618,0.00499612,0.535021 beta-lactamase_156_P25P,beta-lactamase_156_25,TEM-1,beta-lactamase_156,P62593,,YES,25,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.526,-1.526,,,0.624,H,A,0.52,0.14,1.079,,73.08,BOA,-2.15367,0.111618,0.00347571,0.834301 beta-lactamase_156_P60P,beta-lactamase_156_60,TEM-1,beta-lactamase_156,P62593,,YES,60,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-2.469,-2.469,,,0.256,T,A,0.52,-0.56,2.947,,77.62,BOA,-1.97633,0.111618,0.00521318,0.760615 beta-lactamase_156_P65P,beta-lactamase_156_65,TEM-1,beta-lactamase_156,P62593,,YES,65,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.894,-0.894,,,0.098,E,B,0.52,-0.62,0.623,,40.56,HOH,-1.03233,0.111618,0.00152776,0.533365 beta-lactamase_156_Q203Q,beta-lactamase_156_203,TEM-1,beta-lactamase_156,P62593,,YES,203,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.168,-2.168,,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.111618,0.00631514,0.894023 beta-lactamase_156_Q204Q,beta-lactamase_156_204,TEM-1,beta-lactamase_156,P62593,,YES,204,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-1.382,-1.382,,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.111618,0.00364106,0.873749 beta-lactamase_156_Q267Q,beta-lactamase_156_267,TEM-1,beta-lactamase_156,P62593,,YES,267,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.308,-2.308,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.111618,0.0102128,0.903015 beta-lactamase_156_Q276Q,beta-lactamase_156_276,TEM-1,beta-lactamase_156,P62593,,YES,276,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-1.144,-1.144,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.111618,0.0191712,0.827481 beta-lactamase_156_Q37Q,beta-lactamase_156_37,TEM-1,beta-lactamase_156,P62593,,YES,37,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.134,-2.134,,,0.613,H,A,0.64,1.98,12.052,12.052,73.08,APH,-2.06967,0.111618,0.00425833,0.896995 beta-lactamase_156_Q86Q,beta-lactamase_156_86,TEM-1,beta-lactamase_156,P62593,,YES,86,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.4,-2.4,,,0.696,S,A,0.64,2.38,27.704,27.704,77.62,OPA,-1.61067,0.111618,0.00450027,0.894218 beta-lactamase_156_Q88Q,beta-lactamase_156_88,TEM-1,beta-lactamase_156,P62593,,YES,88,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.086,-2.086,,,0.807,,B,0.64,2.03,0.911,,77.62,APH,-1.53433,0.111618,0.00504167,0.897979 beta-lactamase_156_Q97Q,beta-lactamase_156_97,TEM-1,beta-lactamase_156,P62593,,YES,97,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.072,-2.072,,,0.823,G,A,0.64,2.42,4.457,,77.62,PPP,-2.43833,0.111618,0.0045116,0.88305 beta-lactamase_156_R118R,beta-lactamase_156_118,TEM-1,beta-lactamase_156,P62593,,YES,118,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.413,-2.413,,,0.457,H,A,1.2,1.39,2.231,,77.62,HBA,-1.785,0.111618,0.00538794,0.90101 beta-lactamase_156_R159R,beta-lactamase_156_159,TEM-1,beta-lactamase_156,P62593,,YES,159,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-0.94,-0.94,,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.111618,0.00108472,0.84542 beta-lactamase_156_R162R,beta-lactamase_156_162,TEM-1,beta-lactamase_156,P62593,,YES,162,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.016,-1.016,,,0.124,S,B,1.2,-0.37,7.444,,64.69,ABH,-1.25,0.111618,0.000561334,0.811291 beta-lactamase_156_R176R,beta-lactamase_156_176,TEM-1,beta-lactamase_156,P62593,,YES,176,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-0.863,-0.863,,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.111618,0.00105554,0.841004 beta-lactamase_156_R189R,beta-lactamase_156_189,TEM-1,beta-lactamase_156,P62593,,YES,189,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.844,-1.844,,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.111618,0.0050699,0.890323 beta-lactamase_156_R202R,beta-lactamase_156_202,TEM-1,beta-lactamase_156,P62593,,YES,202,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.292,-1.292,,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.111618,0.00321899,0.880513 beta-lactamase_156_R220R,beta-lactamase_156_220,TEM-1,beta-lactamase_156,P62593,,YES,220,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-0.942,-0.942,,,0.295,I,A,1.2,-0.76,2.164,,74.48,HBP,-1.33633,0.111618,0.00232421,0.851182 beta-lactamase_156_R239R,beta-lactamase_156_239,TEM-1,beta-lactamase_156,P62593,,YES,239,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-0.819,-0.819,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.111618,0.00213852,0.787501 beta-lactamase_156_R242R,beta-lactamase_156_242,TEM-1,beta-lactamase_156,P62593,,YES,242,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.319,-1.319,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.111618,0.00452879,0.682633 beta-lactamase_156_R257R,beta-lactamase_156_257,TEM-1,beta-lactamase_156,P62593,,YES,257,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.533,-1.533,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.111618,0.00756629,0.603415 beta-lactamase_156_R273R,beta-lactamase_156_273,TEM-1,beta-lactamase_156,P62593,,YES,273,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.314,-2.314,,,0.564,H,A,1.2,1.57,20.248,20.248,73.78,ABP,-1.841,0.111618,0.0077952,0.8896 beta-lactamase_156_R275R,beta-lactamase_156_275,TEM-1,beta-lactamase_156,P62593,,YES,275,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.397,-1.397,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.111618,0.0141984,0.687095 beta-lactamase_156_R41R,beta-lactamase_156_41,TEM-1,beta-lactamase_156,P62593,,YES,41,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-0.942,-0.942,,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.111618,0.00123327,0.8441 beta-lactamase_156_R59R,beta-lactamase_156_59,TEM-1,beta-lactamase_156,P62593,,YES,59,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.345,-1.345,,,0.329,S,L,1.2,-0.09,2.995,,73.08,HBO,-2.24267,0.111618,0.00318082,0.814027 beta-lactamase_156_R63R,beta-lactamase_156_63,TEM-1,beta-lactamase_156,P62593,,YES,63,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-0.943,-0.943,,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.111618,0.00126938,0.852403 beta-lactamase_156_R81R,beta-lactamase_156_81,TEM-1,beta-lactamase_156,P62593,,YES,81,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.466,-1.466,,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.111618,0.00499763,0.856705 beta-lactamase_156_R91R,beta-lactamase_156_91,TEM-1,beta-lactamase_156,P62593,,YES,91,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.392,-1.392,,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.111618,0.00380226,0.870169 beta-lactamase_156_R92R,beta-lactamase_156_92,TEM-1,beta-lactamase_156,P62593,,YES,92,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.718,-1.718,,,0.479,E,B,1.2,1.36,19.112,19.112,65.38,BBH,-1.50367,0.111618,0.00429626,0.906513 beta-lactamase_156_S104S,beta-lactamase_156_104,TEM-1,beta-lactamase_156,P62593,,YES,104,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.015,-1.015,,,0.04,,b,0.27,0.57,4.02,,63.29,HPO,-1.05267,0.111618,0.00218083,0.785701 beta-lactamase_156_S122S,beta-lactamase_156_122,TEM-1,beta-lactamase_156,P62593,,YES,122,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.406,-2.406,,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.111618,0.00497825,0.949105 beta-lactamase_156_S128S,beta-lactamase_156_128,TEM-1,beta-lactamase_156,P62593,,YES,128,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-0.84,-0.84,,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.111618,0.00071483,0.547038 beta-lactamase_156_S201S,beta-lactamase_156_201,TEM-1,beta-lactamase_156,P62593,,YES,201,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.183,-1.183,,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.111618,0.00198815,0.804582 beta-lactamase_156_S221S,beta-lactamase_156_221,TEM-1,beta-lactamase_156,P62593,,YES,221,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.754,-1.754,,,0.624,H,A,0.27,-0.2,17.729,17.729,74.48,BPH,-1.59967,0.111618,0.0046094,0.892387 beta-lactamase_156_S233S,beta-lactamase_156_233,TEM-1,beta-lactamase_156,P62593,,YES,233,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.886,-1.886,,,0.016,E,B,0.27,-1.01,4.111,,77.62,BPO,-1.17267,0.111618,0.00311415,0.734695 beta-lactamase_156_S241S,beta-lactamase_156_241,TEM-1,beta-lactamase_156,P62593,,YES,241,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.433,-1.433,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.111618,0.00452736,0.826587 beta-lactamase_156_S256S,beta-lactamase_156_256,TEM-1,beta-lactamase_156,P62593,,YES,256,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.621,-1.621,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.111618,0.00710634,0.76457 beta-lactamase_156_S266S,beta-lactamase_156_266,TEM-1,beta-lactamase_156,P62593,,YES,266,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.369,-1.369,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.111618,0.0140785,0.880065 beta-lactamase_156_S283S,beta-lactamase_156_283,TEM-1,beta-lactamase_156,P62593,,YES,283,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.638,-1.638,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.111618,0.0429138,0.881147 beta-lactamase_156_S51S,beta-lactamase_156_51,TEM-1,beta-lactamase_156,P62593,,YES,51,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.526,-1.526,,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.111618,0.00504821,0.877757 beta-lactamase_156_S57S,beta-lactamase_156_57,TEM-1,beta-lactamase_156,P62593,,YES,57,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.918,-1.918,,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.111618,0.00492804,0.87009 beta-lactamase_156_S68S,beta-lactamase_156_68,TEM-1,beta-lactamase_156,P62593,,YES,68,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-0.913,-0.913,,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.111618,0.000800065,0.43491 beta-lactamase_156_S80S,beta-lactamase_156_80,TEM-1,beta-lactamase_156,P62593,,YES,80,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.029,-2.029,,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.111618,0.00565569,0.888555 beta-lactamase_156_S96S,beta-lactamase_156_96,TEM-1,beta-lactamase_156,P62593,,YES,96,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.27,-2.27,,,0.368,,b,0.27,0.39,2.838,,73.78,HPP,-2.019,0.111618,0.00551835,0.90925 beta-lactamase_156_T107T,beta-lactamase_156_107,TEM-1,beta-lactamase_156,P62593,,YES,107,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.117,-1.117,,,,G,A,0.22,-0.06,0.341,,67.83,HPA,-1.265,0.111618,0.00239347,0.763524 beta-lactamase_156_T112T,beta-lactamase_156_112,TEM-1,beta-lactamase_156,P62593,,YES,112,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.186,-2.186,,,0.921,T,A,0.22,1.06,2.87,,73.78,HPA,-1.925,0.111618,0.00531334,0.902142 beta-lactamase_156_T116T,beta-lactamase_156_116,TEM-1,beta-lactamase_156,P62593,,YES,116,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.28,-1.28,,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.111618,0.00336175,0.833988 beta-lactamase_156_T126T,beta-lactamase_156_126,TEM-1,beta-lactamase_156,P62593,,YES,126,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.122,-1.122,,,0.05,H,A,0.22,-0.05,1.14,,44.41,HPH,-1.60467,0.111618,0.00244552,0.806392 beta-lactamase_156_T131T,beta-lactamase_156_131,TEM-1,beta-lactamase_156,P62593,,YES,131,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.328,-1.328,,,,H,A,0.22,-0.69,2.031,,67.48,PPH,-1.00867,0.111618,0.00345886,0.809513 beta-lactamase_156_T138T,beta-lactamase_156_138,TEM-1,beta-lactamase_156,P62593,,YES,138,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.506,-2.506,,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.111618,0.00487868,0.902398 beta-lactamase_156_T139T,beta-lactamase_156_139,TEM-1,beta-lactamase_156,P62593,,YES,139,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.901,-1.901,,,0.216,H,A,0.22,0.39,16.34,16.34,77.62,PPH,-2.04667,0.111618,0.00441837,0.87644 beta-lactamase_156_T147T,beta-lactamase_156_147,TEM-1,beta-lactamase_156,P62593,,YES,147,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.149,-1.149,,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.111618,0.00226017,0.871209 beta-lactamase_156_T158T,beta-lactamase_156_158,TEM-1,beta-lactamase_156,P62593,,YES,158,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.116,-1.116,,,0.036,,B,0.22,-0.85,3.771,,69.58,HPB,-1.269,0.111618,0.00341825,0.784992 beta-lactamase_156_T178T,beta-lactamase_156_178,TEM-1,beta-lactamase_156,P62593,,YES,178,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-0.791,-0.791,,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.111618,0.000684366,0.796804 beta-lactamase_156_T179T,beta-lactamase_156_179,TEM-1,beta-lactamase_156,P62593,,YES,179,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.085,-1.085,,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.111618,0.00226045,0.70078 beta-lactamase_156_T186T,beta-lactamase_156_186,TEM-1,beta-lactamase_156,P62593,,YES,186,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.522,-2.522,,,0.396,H,A,0.22,-0.28,16.606,16.606,77.62,HPP,-1.77633,0.111618,0.00485034,0.905815 beta-lactamase_156_T187T,beta-lactamase_156_187,TEM-1,beta-lactamase_156,P62593,,YES,187,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.401,-1.401,,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.111618,0.00491782,0.790182 beta-lactamase_156_T193T,beta-lactamase_156_193,TEM-1,beta-lactamase_156,P62593,,YES,193,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.914,-1.914,,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.111618,0.00482669,0.904619 beta-lactamase_156_T198T,beta-lactamase_156_198,TEM-1,beta-lactamase_156,P62593,,YES,198,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.168,-2.168,,,0.489,,B,0.22,-0.13,10.771,10.771,73.78,HPH,-1.98767,0.111618,0.004311,0.889139 beta-lactamase_156_T263T,beta-lactamase_156_263,TEM-1,beta-lactamase_156,P62593,,YES,263,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.031,-2.031,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.111618,0.0110582,0.897758 beta-lactamase_156_T264T,beta-lactamase_156_264,TEM-1,beta-lactamase_156,P62593,,YES,264,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.985,-1.985,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.111618,0.0119399,0.830533 beta-lactamase_156_T269T,beta-lactamase_156_269,TEM-1,beta-lactamase_156,P62593,,YES,269,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.156,-2.156,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.111618,0.00950944,0.907698 beta-lactamase_156_T27T,beta-lactamase_156_27,TEM-1,beta-lactamase_156,P62593,,YES,27,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.905,-1.905,,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.111618,0.00306559,0.783564 beta-lactamase_156_T69T,beta-lactamase_156_69,TEM-1,beta-lactamase_156,P62593,,YES,69,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-0.973,-0.973,,,,G,A,0.22,-1.24,4.194,,93.01,PPH,-1.01833,0.111618,0.00127498,0.717377 beta-lactamase_156_V101V,beta-lactamase_156_101,TEM-1,beta-lactamase_156,P62593,,YES,101,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.295,-1.295,,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.111618,0.00374492,0.861359 beta-lactamase_156_V106V,beta-lactamase_156_106,TEM-1,beta-lactamase_156,P62593,,YES,106,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.218,-1.218,,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.111618,0.00304168,0.887132 beta-lactamase_156_V117V,beta-lactamase_156_117,TEM-1,beta-lactamase_156,P62593,,YES,117,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.53,-1.53,,,,H,A,0.44,-0.34,1.182,,65.03,PHB,-1.741,0.111618,0.00467906,0.768081 beta-lactamase_156_V157V,beta-lactamase_156_157,TEM-1,beta-lactamase_156,P62593,,YES,157,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.751,-1.751,,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.111618,0.00506849,0.897831 beta-lactamase_156_V214V,beta-lactamase_156_214,TEM-1,beta-lactamase_156,P62593,,YES,214,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.299,-1.299,,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.111618,0.00628442,0.875847 beta-lactamase_156_V259V,beta-lactamase_156_259,TEM-1,beta-lactamase_156,P62593,,YES,259,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.522,-1.522,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.111618,0.0070773,0.773133 beta-lactamase_156_V260V,beta-lactamase_156_260,TEM-1,beta-lactamase_156,P62593,,YES,260,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.101,-1.101,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.111618,0.00471757,0.767638 beta-lactamase_156_V29V,beta-lactamase_156_29,TEM-1,beta-lactamase_156,P62593,,YES,29,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-2.856,-2.856,,,0.733,H,A,0.44,-0.78,3.685,,93.01,HHB,-2.24733,0.111618,0.00318969,0.914781 beta-lactamase_156_V31V,beta-lactamase_156_31,TEM-1,beta-lactamase_156,P62593,,YES,31,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.822,-1.822,,,,H,A,0.44,-0.46,4.126,,73.78,BHB,-2.03767,0.111618,0.00478065,0.791244 beta-lactamase_156_V42V,beta-lactamase_156_42,TEM-1,beta-lactamase_156,P62593,,YES,42,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.564,-1.564,,,0.017,E,B,0.44,-0.51,2.576,,63.99,BHO,-1.042,0.111618,0.00404515,0.763152 beta-lactamase_156_V72V,beta-lactamase_156_72,TEM-1,beta-lactamase_156,P62593,,YES,72,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.658,-1.658,,,,H,A,0.44,-1.03,1.92,,65.73,BHH,-1.32167,0.111618,0.00501194,0.776934 beta-lactamase_156_V78V,beta-lactamase_156_78,TEM-1,beta-lactamase_156,P62593,,YES,78,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.459,-1.459,,,,H,A,0.44,-0.47,1.132,,63.64,HHH,-1.17833,0.111618,0.00492501,0.782376 beta-lactamase_156_V82V,beta-lactamase_156_82,TEM-1,beta-lactamase_156,P62593,,YES,82,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.325,-1.325,,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.111618,0.00397046,0.865033 beta-lactamase_156_W163W,beta-lactamase_156_163,TEM-1,beta-lactamase_156,P62593,,YES,163,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-1.843,-1.843,,,0.467,,B,0.47,-0.5,15.095,15.095,63.99,BHA,-1.269,0.111618,0.00418955,0.85928 beta-lactamase_156_W208W,beta-lactamase_156_208,TEM-1,beta-lactamase_156,P62593,,YES,208,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-0.818,-0.818,,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.111618,0.00126609,0.719286 beta-lactamase_156_W227W,beta-lactamase_156_227,TEM-1,beta-lactamase_156,P62593,,YES,227,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-0.982,-0.982,,,0.272,,B,0.47,-0.29,2.533,,74.48,OHH,-1.595,0.111618,0.00226019,0.544046 beta-lactamase_156_W288W,beta-lactamase_156_288,TEM-1,beta-lactamase_156,P62593,,YES,288,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,,,,,,,,,,,,,BHO,,0.111618,,0.68495 beta-lactamase_156_Y103Y,beta-lactamase_156_103,TEM-1,beta-lactamase_156,P62593,,YES,103,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-1.33,-1.33,,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.111618,0.00443048,0.876563 beta-lactamase_156_Y262Y,beta-lactamase_156_262,TEM-1,beta-lactamase_156,P62593,,YES,262,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-1.332,-1.332,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.111618,0.00853516,0.737473 beta-lactamase_156_Y44Y,beta-lactamase_156_44,TEM-1,beta-lactamase_156,P62593,,YES,44,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-2.547,-2.547,,,,E,B,0.21,-0.45,2.184,,73.78,OHH,-1.86267,0.111618,0.00426364,0.613609 beta-lactamase_156_Y95Y,beta-lactamase_156_95,TEM-1,beta-lactamase_156,P62593,,YES,95,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-1.715,-1.715,,,0.122,,b,0.21,-0.37,2.341,,77.62,BHP,-2.16167,0.111618,0.00479449,0.763164 beta-lactamase_2500_A123A,beta-lactamase_2500_123,TEM-1,beta-lactamase_2500,P62593,,YES,123,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.834,-0.834,,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.361275,0.0010157,0.571665 beta-lactamase_2500_A124A,beta-lactamase_2500_124,TEM-1,beta-lactamase_2500,P62593,,YES,124,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.181,-1.181,,,,H,A,0.46,-0.9,0.314,,64.34,HHH,-1.152,0.361275,0.00481399,0.616479 beta-lactamase_2500_A132A,beta-lactamase_2500_132,TEM-1,beta-lactamase_2500,P62593,,YES,132,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.9,-0.9,,,,H,A,0.46,-0.93,8.408,,64.69,PHH,-1.138,0.361275,0.000962524,0.482801 beta-lactamase_2500_A133A,beta-lactamase_2500_133,TEM-1,beta-lactamase_2500,P62593,,YES,133,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.186,-1.186,,,,H,A,0.46,-0.86,2.649,,67.83,HHP,-0.988333,0.361275,0.00468022,0.628609 beta-lactamase_2500_A148A,beta-lactamase_2500_148,TEM-1,beta-lactamase_2500,P62593,,YES,148,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.757,-1.757,,,0.379,H,A,0.46,-0.55,2.117,,72.73,PHH,-1.40167,0.361275,0.00547053,0.821012 beta-lactamase_2500_A170A,beta-lactamase_2500_170,TEM-1,beta-lactamase_2500,P62593,,YES,170,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.237,-1.237,,,0.126,,L,0.46,-0.35,2.427,,64.69,AHH,-1.63267,0.361275,0.00431903,0.660484 beta-lactamase_2500_A182A,beta-lactamase_2500_182,TEM-1,beta-lactamase_2500,P62593,,YES,182,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.777,-1.777,,,0.136,H,A,0.46,-0.66,2.032,,93.01,OHH,-1.27367,0.361275,0.00559099,0.758543 beta-lactamase_2500_A183A,beta-lactamase_2500_183,TEM-1,beta-lactamase_2500,P62593,,YES,183,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.231,-1.231,,,0.155,H,A,0.46,-0.91,12.189,,77.62,HHH,-1.53367,0.361275,0.00296631,0.670326 beta-lactamase_2500_A185A,beta-lactamase_2500_185,TEM-1,beta-lactamase_2500,P62593,,YES,185,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.406,-1.406,,,,H,A,0.46,-1.02,2.999,,65.03,HHP,-1.84033,0.361275,0.00467449,0.613712 beta-lactamase_2500_A200A,beta-lactamase_2500_200,TEM-1,beta-lactamase_2500,P62593,,YES,200,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.878,-1.878,,,0.757,H,A,0.46,-0.19,0.436,,77.62,HHP,-2.001,0.361275,0.0060056,0.800082 beta-lactamase_2500_A211A,beta-lactamase_2500_211,TEM-1,beta-lactamase_2500,P62593,,YES,211,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.896,-1.896,,,0.369,T,A,0.46,-0.69,2.061,,77.62,AHA,-1.94633,0.361275,0.00648183,0.81736 beta-lactamase_2500_A215A,beta-lactamase_2500_215,TEM-1,beta-lactamase_2500,P62593,,YES,215,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.503,-1.503,,,,,a,0.46,-0.93,3.516,,74.48,HHO,-1.42633,0.361275,0.00544007,0.567952 beta-lactamase_2500_A222A,beta-lactamase_2500_222,TEM-1,beta-lactamase_2500,P62593,,YES,222,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.103,-2.103,,,0.233,H,A,0.46,-0.25,0.379,,77.62,PHH,-1.63733,0.361275,0.00466094,0.71608 beta-lactamase_2500_A225A,beta-lactamase_2500_225,TEM-1,beta-lactamase_2500,P62593,,YES,225,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.845,-1.845,,,1,T,B,0.46,-0.38,0.551,,74.48,OHO,-1.39967,0.361275,0.00465057,0.790244 beta-lactamase_2500_A230A,beta-lactamase_2500_230,TEM-1,beta-lactamase_2500,P62593,,YES,230,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.154,-1.154,,,0.01,E,B,0.46,-1.17,1.171,,50,HHA,-1.079,0.361275,0.00516841,0.594836 beta-lactamase_2500_A235A,beta-lactamase_2500_235,TEM-1,beta-lactamase_2500,P62593,,YES,235,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.266,-1.266,,,0.32,E,B,0.46,-0.86,0.891,,50,OHO,-0.89,0.361275,0.00493474,0.469029 beta-lactamase_2500_A246A,beta-lactamase_2500_246,TEM-1,beta-lactamase_2500,P62593,,YES,246,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.121,-2.121,,,0.01,E,B,0.46,-1.01,0.753,,73.78,HHH,-1.55633,0.361275,0.00569458,0.547426 beta-lactamase_2500_A247A,beta-lactamase_2500_247,TEM-1,beta-lactamase_2500,P62593,,YES,247,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.48,-1.48,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.361275,0.00611275,0.570435 beta-lactamase_2500_A268A,beta-lactamase_2500_268,TEM-1,beta-lactamase_2500,P62593,,YES,268,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.023,-2.023,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.361275,0.0102525,0.744182 beta-lactamase_2500_A278A,beta-lactamase_2500_278,TEM-1,beta-lactamase_2500,P62593,,YES,278,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.348,-1.348,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.361275,0.0310297,0.617001 beta-lactamase_2500_A282A,beta-lactamase_2500_282,TEM-1,beta-lactamase_2500,P62593,,YES,282,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.586,-1.586,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.361275,0.0449821,0.64905 beta-lactamase_2500_A34A,beta-lactamase_2500_34,TEM-1,beta-lactamase_2500,P62593,,YES,34,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.059,-2.059,,,,H,A,0.46,-0.54,2.921,,73.78,AHA,-1.74967,0.361275,0.00407913,0.64669 beta-lactamase_2500_A40A,beta-lactamase_2500_40,TEM-1,beta-lactamase_2500,P62593,,YES,40,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.402,-1.402,,,0.155,S,B,0.46,0.21,0.953,,73.78,OHB,-1.40267,0.361275,0.00490026,0.530563 beta-lactamase_2500_A77A,beta-lactamase_2500_77,TEM-1,beta-lactamase_2500,P62593,,YES,77,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.234,-1.234,,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.361275,0.00282362,0.676166 beta-lactamase_2500_A84A,beta-lactamase_2500_84,TEM-1,beta-lactamase_2500,P62593,,YES,84,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.651,-1.651,,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.361275,0.00503822,0.76157 beta-lactamase_2500_C121C,beta-lactamase_2500_121,TEM-1,beta-lactamase_2500,P62593,,YES,121,C,C,CC,Special,Special,5.07,5.07,0,0,121,121,0,108.5,108.5,0,-0.953,-0.953,,,,H,A,0.46,-0.81,1.174,,63.29,HOP,-1.46767,0.361275,0.000744322,0.489965 beta-lactamase_2500_C75C,beta-lactamase_2500_75,TEM-1,beta-lactamase_2500,P62593,,YES,75,C,C,CC,Special,Special,5.07,5.07,0,0,121,121,0,108.5,108.5,0,-1.245,-1.245,,,,H,A,0.46,-0.87,0.844,,50,HOO,-1.24333,0.361275,0.0034616,0.622009 beta-lactamase_2500_D113D,beta-lactamase_2500_113,TEM-1,beta-lactamase_2500,P62593,,YES,113,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.829,-1.829,,,0.665,T,A,0.75,0.91,21.104,21.104,73.08,PAO,-1.703,0.361275,0.00474112,0.804851 beta-lactamase_2500_D129D,beta-lactamase_2500_129,TEM-1,beta-lactamase_2500,P62593,,YES,129,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.816,-0.816,,,,,B,0.75,-0.69,1.29,,34.97,PAP,-0.818,0.361275,0.00109178,0.449359 beta-lactamase_2500_D155D,beta-lactamase_2500_155,TEM-1,beta-lactamase_2500,P62593,,YES,155,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.889,-0.889,,,0.049,,B,0.75,-0.9,2.386,,64.69,OAB,-1.62267,0.361275,0.00135315,0.496826 beta-lactamase_2500_D161D,beta-lactamase_2500_161,TEM-1,beta-lactamase_2500,P62593,,YES,161,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.891,-0.891,,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.361275,0.000897697,0.403799 beta-lactamase_2500_D174D,beta-lactamase_2500_174,TEM-1,beta-lactamase_2500,P62593,,YES,174,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.738,-0.738,,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.361275,0.00125633,0.394169 beta-lactamase_2500_D177D,beta-lactamase_2500_177,TEM-1,beta-lactamase_2500,P62593,,YES,177,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.967,-0.967,,,0.006,T,L,0.75,-1.02,4.131,,64.69,BAP,-0.873667,0.361275,0.000864022,0.418565 beta-lactamase_2500_D207D,beta-lactamase_2500_207,TEM-1,beta-lactamase_2500,P62593,,YES,207,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.064,-2.064,,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.361275,0.00592942,0.820782 beta-lactamase_2500_D212D,beta-lactamase_2500_212,TEM-1,beta-lactamase_2500,P62593,,YES,212,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.624,-1.624,,,0.037,,b,0.75,-0.58,12.482,,74.48,HAB,-1.77667,0.361275,0.00644302,0.569444 beta-lactamase_2500_D231D,beta-lactamase_2500_231,TEM-1,beta-lactamase_2500,P62593,,YES,231,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.816,-0.816,,,,E,B,0.75,-1.06,0.319,,65.38,HAB,-0.994,0.361275,0.00107395,0.505645 beta-lactamase_2500_D252D,beta-lactamase_2500_252,TEM-1,beta-lactamase_2500,P62593,,YES,252,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.94,-1.94,,,0.766,,B,1.59,1.16,,,67.83,OAO,-2.0965,0.361275,0.00575769,0.756906 beta-lactamase_2500_D271D,beta-lactamase_2500_271,TEM-1,beta-lactamase_2500,P62593,,YES,271,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.249,-1.249,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.361275,0.00752082,0.672219 beta-lactamase_2500_D33D,beta-lactamase_2500_33,TEM-1,beta-lactamase_2500,P62593,,YES,33,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.321,-2.321,,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.361275,0.00435556,0.808453 beta-lactamase_2500_D36D,beta-lactamase_2500_36,TEM-1,beta-lactamase_2500,P62593,,YES,36,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.732,-2.732,,,0.555,H,A,0.75,1.17,2.26,,77.62,AAP,-1.91167,0.361275,0.00476483,0.82542 beta-lactamase_2500_D48D,beta-lactamase_2500_48,TEM-1,beta-lactamase_2500,P62593,,YES,48,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.101,-1.101,,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.361275,0.0027273,0.418999 beta-lactamase_2500_D83D,beta-lactamase_2500_83,TEM-1,beta-lactamase_2500,P62593,,YES,83,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.066,-1.066,,,0.354,H,A,0.75,0.22,0.239,,48.95,HAH,-1.34733,0.361275,0.00205968,0.41248 beta-lactamase_2500_D99D,beta-lactamase_2500_99,TEM-1,beta-lactamase_2500,P62593,,YES,99,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.191,-1.191,,,0.402,G,A,0.75,0.36,1.318,,64.69,PAH,-1.794,0.361275,0.00305446,0.582328 beta-lactamase_2500_E102E,beta-lactamase_2500_102,TEM-1,beta-lactamase_2500,P62593,,YES,102,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.118,-2.118,,,0.722,S,B,1.04,1.82,1.336,,73.08,HAH,-1.581,0.361275,0.00486633,0.786238 beta-lactamase_2500_E108E,beta-lactamase_2500_108,TEM-1,beta-lactamase_2500,P62593,,YES,108,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.46,-1.46,,,0.572,G,A,1.04,1.87,1.147,,72.73,PAB,-1.437,0.361275,0.00413372,0.767281 beta-lactamase_2500_E119E,beta-lactamase_2500_119,TEM-1,beta-lactamase_2500,P62593,,YES,119,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.412,-1.412,,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.361275,0.00386966,0.529885 beta-lactamase_2500_E145E,beta-lactamase_2500_145,TEM-1,beta-lactamase_2500,P62593,,YES,145,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.357,-2.357,,,0.545,H,A,1.04,0.79,2.124,,77.62,BAH,-2.069,0.361275,0.00553285,0.850792 beta-lactamase_2500_E164E,beta-lactamase_2500_164,TEM-1,beta-lactamase_2500,P62593,,YES,164,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-0.948,-0.948,,,0.011,T,B,1.04,-0.4,0.352,,64.69,HAO,-1.388,0.361275,0.00137286,0.39722 beta-lactamase_2500_E166E,beta-lactamase_2500_166,TEM-1,beta-lactamase_2500,P62593,,YES,166,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.756,-1.756,,,0.508,G,A,1.04,1.05,2.124,,73.08,OAH,-1.42233,0.361275,0.00512989,0.818241 beta-lactamase_2500_E169E,beta-lactamase_2500_169,TEM-1,beta-lactamase_2500,P62593,,YES,169,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.23,-1.23,,,0.337,,A,1.04,1,1.806,,73.08,PAH,-1.16533,0.361275,0.00400994,0.717239 beta-lactamase_2500_E175E,beta-lactamase_2500_175,TEM-1,beta-lactamase_2500,P62593,,YES,175,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.336,-2.336,,,0.551,,A,1.04,1.05,5.316,,77.62,AAB,-1.31233,0.361275,0.00482205,0.849767 beta-lactamase_2500_E195E,beta-lactamase_2500_195,TEM-1,beta-lactamase_2500,P62593,,YES,195,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.186,-2.186,,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.361275,0.00496565,0.818106 beta-lactamase_2500_E210E,beta-lactamase_2500_210,TEM-1,beta-lactamase_2500,P62593,,YES,210,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.319,-2.319,,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.361275,0.00663582,0.845072 beta-lactamase_2500_E238E,beta-lactamase_2500_238,TEM-1,beta-lactamase_2500,P62593,,YES,238,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.002,-2.002,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.361275,0.00743256,0.753749 beta-lactamase_2500_E26E,beta-lactamase_2500_26,TEM-1,beta-lactamase_2500,P62593,,YES,26,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.454,-2.454,,,0.54,H,A,1.04,0.98,0.49,,93.01,OAP,-1.96167,0.361275,0.00297948,0.83109 beta-lactamase_2500_E272E,beta-lactamase_2500_272,TEM-1,beta-lactamase_2500,P62593,,YES,272,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.127,-1.127,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.361275,0.00545371,0.641708 beta-lactamase_2500_E279E,beta-lactamase_2500_279,TEM-1,beta-lactamase_2500,P62593,,YES,279,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.038,-1.038,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.361275,0.0192826,0.539443 beta-lactamase_2500_E35E,beta-lactamase_2500_35,TEM-1,beta-lactamase_2500,P62593,,YES,35,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-0.869,-0.869,,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.361275,0.00174441,0.453291 beta-lactamase_2500_E46E,beta-lactamase_2500_46,TEM-1,beta-lactamase_2500,P62593,,YES,46,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.94,-1.94,,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.361275,0.00427568,0.602893 beta-lactamase_2500_E56E,beta-lactamase_2500_56,TEM-1,beta-lactamase_2500,P62593,,YES,56,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.043,-2.043,,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.361275,0.00238534,0.560295 beta-lactamase_2500_E61E,beta-lactamase_2500_61,TEM-1,beta-lactamase_2500,P62593,,YES,61,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.115,-2.115,,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.361275,0.00440955,0.818361 beta-lactamase_2500_E62E,beta-lactamase_2500_62,TEM-1,beta-lactamase_2500,P62593,,YES,62,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.193,-1.193,,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.361275,0.00264802,0.523679 beta-lactamase_2500_E87E,beta-lactamase_2500_87,TEM-1,beta-lactamase_2500,P62593,,YES,87,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.421,-1.421,,,0.048,,B,1.04,0.92,17.923,17.923,64.69,PAP,-1.969,0.361275,0.00337888,0.646559 beta-lactamase_2500_F149F,beta-lactamase_2500_149,TEM-1,beta-lactamase_2500,P62593,,YES,149,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.299,-1.299,,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.361275,0.00418462,0.5979 beta-lactamase_2500_F228F,beta-lactamase_2500_228,TEM-1,beta-lactamase_2500,P62593,,YES,228,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-2.342,-2.342,,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.361275,0.0046669,0.63989 beta-lactamase_2500_F58F,beta-lactamase_2500_58,TEM-1,beta-lactamase_2500,P62593,,YES,58,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-2.914,-2.914,,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.361275,0.00523369,0.630669 beta-lactamase_2500_F64F,beta-lactamase_2500_64,TEM-1,beta-lactamase_2500,P62593,,YES,64,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-0.841,-0.841,,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.361275,0.000947691,0.408709 beta-lactamase_2500_F70F,beta-lactamase_2500_70,TEM-1,beta-lactamase_2500,P62593,,YES,70,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.169,-1.169,,,,H,A,0.58,-1.34,1.918,,63.99,PHB,-0.980667,0.361275,0.00193499,0.617516 beta-lactamase_2500_G114G,beta-lactamase_2500_114,TEM-1,beta-lactamase_2500,P62593,,YES,114,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.094,-1.094,,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.361275,0.00224919,0.563313 beta-lactamase_2500_G141G,beta-lactamase_2500_141,TEM-1,beta-lactamase_2500,P62593,,YES,141,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.828,-0.828,,,0.575,T,l,0.29,-0.28,1.493,,64.69,HOO,-1.08933,0.361275,0.0012419,0.451032 beta-lactamase_2500_G142G,beta-lactamase_2500_142,TEM-1,beta-lactamase_2500,P62593,,YES,142,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.707,-0.707,,,0.034,,p,0.29,-0.64,1.883,,64.69,OOO,-0.834,0.361275,0.00060149,0.549117 beta-lactamase_2500_G154G,beta-lactamase_2500_154,TEM-1,beta-lactamase_2500,P62593,,YES,154,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.823,-0.823,,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.361275,0.00180205,0.480603 beta-lactamase_2500_G194G,beta-lactamase_2500_194,TEM-1,beta-lactamase_2500,P62593,,YES,194,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.396,-1.396,,,0.276,S,b,0.29,0.36,3.593,,67.83,POA,-1.832,0.361275,0.00392163,0.665668 beta-lactamase_2500_G216G,beta-lactamase_2500_216,TEM-1,beta-lactamase_2500,P62593,,YES,216,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.477,-1.477,,,0.437,I,A,0.29,-0.58,1.983,,74.48,HOO,-1.68067,0.361275,0.00639568,0.666313 beta-lactamase_2500_G226G,beta-lactamase_2500_226,TEM-1,beta-lactamase_2500,P62593,,YES,226,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.461,-1.461,,,0.701,T,l,0.29,-0.25,5.086,,74.48,HOH,-1.42933,0.361275,0.00665294,0.669318 beta-lactamase_2500_G234G,beta-lactamase_2500_234,TEM-1,beta-lactamase_2500,P62593,,YES,234,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.62,-0.62,,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.361275,0.000889577,0.531018 beta-lactamase_2500_G236G,beta-lactamase_2500_236,TEM-1,beta-lactamase_2500,P62593,,YES,236,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.784,-0.784,,,0.241,,b,0.29,-0.59,2.14,,64.69,HOO,-1.025,0.361275,0.00162372,0.41308 beta-lactamase_2500_G240G,beta-lactamase_2500_240,TEM-1,beta-lactamase_2500,P62593,,YES,240,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.537,-1.537,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.361275,0.00591201,0.617522 beta-lactamase_2500_G243G,beta-lactamase_2500_243,TEM-1,beta-lactamase_2500,P62593,,YES,243,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.532,-1.532,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.361275,0.00464034,0.551258 beta-lactamase_2500_G249G,beta-lactamase_2500_249,TEM-1,beta-lactamase_2500,P62593,,YES,249,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.312,-1.312,,,0.256,S,B,0.23,0.04,30.841,30.841,72.73,HOO,-1.81367,0.361275,0.00220169,0.51306 beta-lactamase_2500_G253G,beta-lactamase_2500_253,TEM-1,beta-lactamase_2500,P62593,,YES,253,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-2.253,-2.253,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.361275,0.00786358,0.720422 beta-lactamase_2500_G265G,beta-lactamase_2500_265,TEM-1,beta-lactamase_2500,P62593,,YES,265,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-2.58,-2.58,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.361275,0.00811926,0.752512 beta-lactamase_2500_G281G,beta-lactamase_2500_281,TEM-1,beta-lactamase_2500,P62593,,YES,281,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-2.247,-2.247,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.361275,0.0406482,0.672873 beta-lactamase_2500_G39G,beta-lactamase_2500_39,TEM-1,beta-lactamase_2500,P62593,,YES,39,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.864,-1.864,,,0.701,T,L,0.29,0.47,29.926,29.926,77.62,HOH,-1.53633,0.361275,0.00487611,0.81098 beta-lactamase_2500_G43G,beta-lactamase_2500_43,TEM-1,beta-lactamase_2500,P62593,,YES,43,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.62,-0.62,,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.361275,0.00120151,0.4953 beta-lactamase_2500_G52G,beta-lactamase_2500_52,TEM-1,beta-lactamase_2500,P62593,,YES,52,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.149,-1.149,,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.361275,0.00340138,0.515423 beta-lactamase_2500_G76G,beta-lactamase_2500_76,TEM-1,beta-lactamase_2500,P62593,,YES,76,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.189,-1.189,,,,H,A,0.29,-0.67,1.012,,67.83,OOH,-1.22267,0.361275,0.00476637,0.614373 beta-lactamase_2500_G85G,beta-lactamase_2500_85,TEM-1,beta-lactamase_2500,P62593,,YES,85,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.011,-1.011,,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.361275,0.00252173,0.652364 beta-lactamase_2500_G90G,beta-lactamase_2500_90,TEM-1,beta-lactamase_2500,P62593,,YES,90,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-2.091,-2.091,,,0.598,T,A,0.29,0.32,1.2,,77.62,HOB,-1.52633,0.361275,0.00490273,0.804808 beta-lactamase_2500_H110H,beta-lactamase_2500_110,TEM-1,beta-lactamase_2500,P62593,,YES,110,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-1.706,-1.706,,,0.341,G,a,0.17,1.08,31.31,31.31,64.69,BBH,-1.73333,0.361275,0.00441499,0.690138 beta-lactamase_2500_H151H,beta-lactamase_2500_151,TEM-1,beta-lactamase_2500,P62593,,YES,151,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-2.96,-2.96,,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.361275,0.00216946,0.794736 beta-lactamase_2500_H156H,beta-lactamase_2500_156,TEM-1,beta-lactamase_2500,P62593,,YES,156,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-3.156,-3.156,,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.361275,0.00468596,0.807527 beta-lactamase_2500_H24H,beta-lactamase_2500_24,TEM-1,beta-lactamase_2500,P62593,,YES,24,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-2.481,-2.481,,,,,,,,0.467,,93.01,OBO,-2.0035,0.361275,0.00238894,0.762261 beta-lactamase_2500_H287H,beta-lactamase_2500_287,TEM-1,beta-lactamase_2500,P62593,,YES,287,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,,,,,,,,,,,,,BBH,-1.111,0.361275,,0.737966 beta-lactamase_2500_H94H,beta-lactamase_2500_94,TEM-1,beta-lactamase_2500,P62593,,YES,94,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-2.5,-2.5,,,0.776,,B,0.17,1.24,1.176,,77.62,HBH,-1.872,0.361275,0.00389226,0.82249 beta-lactamase_2500_I125I,beta-lactamase_2500_125,TEM-1,beta-lactamase_2500,P62593,,YES,125,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.441,-1.441,,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.361275,0.00383964,0.583916 beta-lactamase_2500_I140I,beta-lactamase_2500_140,TEM-1,beta-lactamase_2500,P62593,,YES,140,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.733,-1.733,,,0.128,H,A,0.48,0.41,1.628,,73.08,PHO,-1.48733,0.361275,0.00597777,0.650542 beta-lactamase_2500_I171I,beta-lactamase_2500_171,TEM-1,beta-lactamase_2500,P62593,,YES,171,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-2.431,-2.431,,,0.361,,B,0.48,0.53,1.66,,77.62,HHO,-1.55533,0.361275,0.00623355,0.837724 beta-lactamase_2500_I206I,beta-lactamase_2500_206,TEM-1,beta-lactamase_2500,P62593,,YES,206,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-2.429,-2.429,,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.361275,0.00528934,0.762158 beta-lactamase_2500_I229I,beta-lactamase_2500_229,TEM-1,beta-lactamase_2500,P62593,,YES,229,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.267,-1.267,,,0.083,E,B,0.48,-0.76,3.875,,50,HHH,-1.58767,0.361275,0.00477249,0.563579 beta-lactamase_2500_I244I,beta-lactamase_2500_244,TEM-1,beta-lactamase_2500,P62593,,YES,244,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.555,-1.555,,,,E,B,0.48,-0.84,1.683,,77.62,OHH,-1.385,0.361275,0.00605379,0.537158 beta-lactamase_2500_I245I,beta-lactamase_2500_245,TEM-1,beta-lactamase_2500,P62593,,YES,245,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.068,-1.068,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.361275,0.00391032,0.537607 beta-lactamase_2500_I258I,beta-lactamase_2500_258,TEM-1,beta-lactamase_2500,P62593,,YES,258,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.975,-1.975,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.361275,0.007931,0.578082 beta-lactamase_2500_I261I,beta-lactamase_2500_261,TEM-1,beta-lactamase_2500,P62593,,YES,261,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-2.88,-2.88,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.361275,0.0123091,0.517077 beta-lactamase_2500_I277I,beta-lactamase_2500_277,TEM-1,beta-lactamase_2500,P62593,,YES,277,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.869,-1.869,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.361275,0.0169305,0.751592 beta-lactamase_2500_I280I,beta-lactamase_2500_280,TEM-1,beta-lactamase_2500,P62593,,YES,280,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.708,-1.708,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.361275,0.0530888,0.754126 beta-lactamase_2500_I285I,beta-lactamase_2500_285,TEM-1,beta-lactamase_2500,P62593,,YES,285,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.845,-1.845,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.361275,0.101555,0.727539 beta-lactamase_2500_I45I,beta-lactamase_2500_45,TEM-1,beta-lactamase_2500,P62593,,YES,45,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-2.421,-2.421,,,,E,B,0.48,-0.3,3.793,,77.62,HHA,-2.30267,0.361275,0.00452842,0.602301 beta-lactamase_2500_I54I,beta-lactamase_2500_54,TEM-1,beta-lactamase_2500,P62593,,YES,54,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-2.838,-2.838,,,0.669,E,B,0.48,-0.14,3.946,,73.78,BHH,-2.337,0.361275,0.00403589,0.674034 beta-lactamase_2500_I93I,beta-lactamase_2500_93,TEM-1,beta-lactamase_2500,P62593,,YES,93,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.401,-1.401,,,0.128,E,B,0.48,0.44,19.374,19.374,67.83,BHB,-1.873,0.361275,0.00527066,0.588716 beta-lactamase_2500_K109K,beta-lactamase_2500_109,TEM-1,beta-lactamase_2500,P62593,,YES,109,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.734,-1.734,,,0.787,G,A,2.34,2.21,0.998,,72.73,ABB,-1.63333,0.361275,0.00462493,0.80551 beta-lactamase_2500_K144K,beta-lactamase_2500_144,TEM-1,beta-lactamase_2500,P62593,,YES,144,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-2.388,-2.388,,,0.863,H,A,2.34,1.27,0.515,,77.62,OBA,-1.904,0.361275,0.00481141,0.851763 beta-lactamase_2500_K190K,beta-lactamase_2500_190,TEM-1,beta-lactamase_2500,P62593,,YES,190,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.994,-1.994,,,0.371,H,A,2.34,0.16,29.753,29.753,77.62,BBH,-1.64167,0.361275,0.00574527,0.868928 beta-lactamase_2500_K213K,beta-lactamase_2500_213,TEM-1,beta-lactamase_2500,P62593,,YES,213,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.81,-1.81,,,0.67,,A,2.34,0.29,1.668,,67.83,ABH,-1.57767,0.361275,0.00610411,0.801876 beta-lactamase_2500_K232K,beta-lactamase_2500_232,TEM-1,beta-lactamase_2500,P62593,,YES,232,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.012,-1.012,,,,E,B,2.34,-1.1,3.048,,65.03,ABP,-1.238,0.361275,0.00313441,0.485333 beta-lactamase_2500_K254K,beta-lactamase_2500_254,TEM-1,beta-lactamase_2500,P62593,,YES,254,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-2.126,-2.126,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.361275,0.00369,0.724224 beta-lactamase_2500_K286K,beta-lactamase_2500_286,TEM-1,beta-lactamase_2500,P62593,,YES,286,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.111,-1.111,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.361275,,0.594139 beta-lactamase_2500_K30K,beta-lactamase_2500_30,TEM-1,beta-lactamase_2500,P62593,,YES,30,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-2.307,-2.307,,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.361275,0.00448593,0.657357 beta-lactamase_2500_K32K,beta-lactamase_2500_32,TEM-1,beta-lactamase_2500,P62593,,YES,32,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.984,-1.984,,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.361275,0.00401283,0.798306 beta-lactamase_2500_K53K,beta-lactamase_2500_53,TEM-1,beta-lactamase_2500,P62593,,YES,53,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-2.313,-2.313,,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.361275,0.00383383,0.833359 beta-lactamase_2500_K71K,beta-lactamase_2500_71,TEM-1,beta-lactamase_2500,P62593,,YES,71,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-0.8,-0.8,,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.361275,0.00103192,0.413088 beta-lactamase_2500_L100L,beta-lactamase_2500_100,TEM-1,beta-lactamase_2500,P62593,,YES,100,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.218,-1.218,,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.361275,0.00413885,0.517311 beta-lactamase_2500_L111L,beta-lactamase_2500_111,TEM-1,beta-lactamase_2500,P62593,,YES,111,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.76,-1.76,,,0.328,T,A,0.55,0.93,1.966,,64.34,BHP,-1.884,0.361275,0.00480671,0.761092 beta-lactamase_2500_L120L,beta-lactamase_2500_120,TEM-1,beta-lactamase_2500,P62593,,YES,120,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.044,-1.044,,,,H,A,0.55,-1.13,2.48,,64.69,AHO,-1.13633,0.361275,0.00143563,0.550731 beta-lactamase_2500_L135L,beta-lactamase_2500_135,TEM-1,beta-lactamase_2500,P62593,,YES,135,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.002,-1.002,,,0.117,H,A,0.55,-0.58,0.795,,43.71,PHH,-1.03767,0.361275,0.00244423,0.580944 beta-lactamase_2500_L136L,beta-lactamase_2500_136,TEM-1,beta-lactamase_2500,P62593,,YES,136,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.232,-1.232,,,,H,A,0.55,-0.34,1.36,,48.95,HHH,-1.088,0.361275,0.00442304,0.594942 beta-lactamase_2500_L137L,beta-lactamase_2500_137,TEM-1,beta-lactamase_2500,P62593,,YES,137,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.03,-1.03,,,,H,A,0.55,-0.38,0.769,,42.31,HHP,-1.58933,0.361275,0.00278599,0.593556 beta-lactamase_2500_L146L,beta-lactamase_2500_146,TEM-1,beta-lactamase_2500,P62593,,YES,146,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.462,-1.462,,,0.007,H,A,0.55,-0.56,1.578,,64.69,AHP,-1.656,0.361275,0.00474542,0.596985 beta-lactamase_2500_L150L,beta-lactamase_2500_150,TEM-1,beta-lactamase_2500,P62593,,YES,150,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.326,-1.326,,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.361275,0.00463171,0.627451 beta-lactamase_2500_L160L,beta-lactamase_2500_160,TEM-1,beta-lactamase_2500,P62593,,YES,160,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.977,-0.977,,,0.022,,B,0.55,-0.6,0.895,,44.41,BHA,-0.936,0.361275,0.00193775,0.579935 beta-lactamase_2500_L167L,beta-lactamase_2500_167,TEM-1,beta-lactamase_2500,P62593,,YES,167,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.138,-1.138,,,0.015,G,A,0.55,-0.63,7.813,,64.69,AHP,-1.30767,0.361275,0.00303566,0.61184 beta-lactamase_2500_L188L,beta-lactamase_2500_188,TEM-1,beta-lactamase_2500,P62593,,YES,188,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.166,-1.166,,,,H,A,0.55,-0.3,17.865,17.865,60.14,PHB,-1.47033,0.361275,0.00295687,0.625029 beta-lactamase_2500_L191L,beta-lactamase_2500_191,TEM-1,beta-lactamase_2500,P62593,,YES,191,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.087,-1.087,,,,H,A,0.55,0.09,1.703,,63.29,BHH,-1.445,0.361275,0.00263549,0.598566 beta-lactamase_2500_L192L,beta-lactamase_2500_192,TEM-1,beta-lactamase_2500,P62593,,YES,192,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.254,-1.254,,,0.095,H,A,0.55,0.35,1.902,,60.14,HHP,-1.41833,0.361275,0.00558728,0.605305 beta-lactamase_2500_L196L,beta-lactamase_2500_196,TEM-1,beta-lactamase_2500,P62593,,YES,196,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-2.478,-2.478,,,0.518,S,A,0.55,1.35,7.897,,77.62,AHH,-1.839,0.361275,0.00512144,0.848568 beta-lactamase_2500_L197L,beta-lactamase_2500_197,TEM-1,beta-lactamase_2500,P62593,,YES,197,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.853,-0.853,,,0.007,S,B,0.55,0.33,2.421,,60.14,HHP,-1.833,0.361275,0.00144602,0.513328 beta-lactamase_2500_L199L,beta-lactamase_2500_199,TEM-1,beta-lactamase_2500,P62593,,YES,199,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-2.942,-2.942,,,0.832,H,A,0.55,0.42,15.504,15.504,77.62,PHH,-2.32933,0.361275,0.0048649,0.854708 beta-lactamase_2500_L205L,beta-lactamase_2500_205,TEM-1,beta-lactamase_2500,P62593,,YES,205,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.922,-0.922,,,,H,A,0.55,-0.46,0.831,,42.31,PHH,-1.57767,0.361275,0.00255802,0.55549 beta-lactamase_2500_L218L,beta-lactamase_2500_218,TEM-1,beta-lactamase_2500,P62593,,YES,218,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.391,-1.391,,,,I,b,0.55,-0.53,9.151,9.151,74.48,OHH,-1.58867,0.361275,0.00618274,0.553099 beta-lactamase_2500_L219L,beta-lactamase_2500_219,TEM-1,beta-lactamase_2500,P62593,,YES,219,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.313,-1.313,,,,I,A,0.55,-0.51,35.994,35.994,74.48,HHB,-1.21533,0.361275,0.00664345,0.591862 beta-lactamase_2500_L223L,beta-lactamase_2500_223,TEM-1,beta-lactamase_2500,P62593,,YES,223,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.055,-1.055,,,0.27,,B,0.55,0.09,1.334,,74.48,HHO,-1.35033,0.361275,0.00372793,0.515802 beta-lactamase_2500_L248L,beta-lactamase_2500_248,TEM-1,beta-lactamase_2500,P62593,,YES,248,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.794,-1.794,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.361275,0.00428493,0.522633 beta-lactamase_2500_L284L,beta-lactamase_2500_284,TEM-1,beta-lactamase_2500,P62593,,YES,284,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.981,-1.981,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.361275,0.0686156,0.768141 beta-lactamase_2500_L28L,beta-lactamase_2500_28,TEM-1,beta-lactamase_2500,P62593,,YES,28,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.579,-1.579,,,0.277,H,A,0.55,-0.16,2.716,,93.01,PHH,-2.11333,0.361275,0.00359321,0.666058 beta-lactamase_2500_L38L,beta-lactamase_2500_38,TEM-1,beta-lactamase_2500,P62593,,YES,38,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.343,-1.343,,,0.088,H,A,0.55,0.2,2.71,,64.34,PHO,-1.78033,0.361275,0.00373244,0.62649 beta-lactamase_2500_L47L,beta-lactamase_2500_47,TEM-1,beta-lactamase_2500,P62593,,YES,47,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.876,-1.876,,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.361275,0.00439844,0.585024 beta-lactamase_2500_L49L,beta-lactamase_2500_49,TEM-1,beta-lactamase_2500,P62593,,YES,49,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.897,-1.897,,,0.131,T,A,0.55,0.04,6.681,,64.69,AHP,-1.99233,0.361275,0.00401477,0.698049 beta-lactamase_2500_L55L,beta-lactamase_2500_55,TEM-1,beta-lactamase_2500,P62593,,YES,55,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.86,-1.86,,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.361275,0.00403741,0.610474 beta-lactamase_2500_L73L,beta-lactamase_2500_73,TEM-1,beta-lactamase_2500,P62593,,YES,73,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.507,-1.507,,,,H,A,0.55,-0.64,2.178,,67.83,HHH,-1.487,0.361275,0.00488983,0.610069 beta-lactamase_2500_L74L,beta-lactamase_2500_74,TEM-1,beta-lactamase_2500,P62593,,YES,74,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.296,-1.296,,,,H,A,0.55,-0.91,0.746,,50,HHO,-1.34933,0.361275,0.00493255,0.586294 beta-lactamase_2500_L79L,beta-lactamase_2500_79,TEM-1,beta-lactamase_2500,P62593,,YES,79,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.842,-0.842,,,0.007,H,A,0.55,-0.16,0.823,,50.35,HHP,-1.44333,0.361275,0.000947397,0.525445 beta-lactamase_2500_L89L,beta-lactamase_2500_89,TEM-1,beta-lactamase_2500,P62593,,YES,89,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.096,-1.096,,,0.168,T,A,0.55,0.63,2.066,,64.34,PHO,-1.75767,0.361275,0.00207068,0.467168 beta-lactamase_2500_M115M,beta-lactamase_2500_115,TEM-1,beta-lactamase_2500,P62593,,YES,115,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.389,-1.389,,,0.019,E,B,0.55,0.08,3.261,,69.58,OHP,-1.25433,0.361275,0.0034337,0.586397 beta-lactamase_2500_M127M,beta-lactamase_2500_127,TEM-1,beta-lactamase_2500,P62593,,YES,127,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-2.251,-2.251,,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.361275,0.00437927,0.772465 beta-lactamase_2500_M153M,beta-lactamase_2500_153,TEM-1,beta-lactamase_2500,P62593,,YES,153,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-3.193,-3.193,,,0.14,T,A,0.55,-0.11,3.409,,77.62,PHO,-2.25767,0.361275,0.00509109,0.719208 beta-lactamase_2500_M180M,beta-lactamase_2500_180,TEM-1,beta-lactamase_2500,P62593,,YES,180,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-2.795,-2.795,,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.361275,0.00552048,0.808246 beta-lactamase_2500_M184M,beta-lactamase_2500_184,TEM-1,beta-lactamase_2500,P62593,,YES,184,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.593,-1.593,,,,H,A,0.55,-0.87,2.893,,62.94,HHH,-1.41,0.361275,0.00356019,0.595802 beta-lactamase_2500_M209M,beta-lactamase_2500_209,TEM-1,beta-lactamase_2500,P62593,,YES,209,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.442,-1.442,,,,H,A,0.55,-0.97,3.229,,64.69,HHA,-1.52633,0.361275,0.00625021,0.546119 beta-lactamase_2500_M270M,beta-lactamase_2500_270,TEM-1,beta-lactamase_2500,P62593,,YES,270,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.723,-1.723,,,0.422,H,A,1.59,1.15,2.029,,64.34,PHA,-1.70933,0.361275,0.00767762,0.762445 beta-lactamase_2500_M66M,beta-lactamase_2500_66,TEM-1,beta-lactamase_2500,P62593,,YES,66,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.362,-1.362,,,0.013,,A,0.55,-0.7,0.502,,73.08,OHH,-1.49567,0.361275,0.00412876,0.596132 beta-lactamase_2500_M67M,beta-lactamase_2500_67,TEM-1,beta-lactamase_2500,P62593,,YES,67,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-2.231,-2.231,,,0.006,G,P,0.55,-0.81,2.653,,65.03,HHP,-1.502,0.361275,0.00409753,0.614487 beta-lactamase_2500_N130N,beta-lactamase_2500_130,TEM-1,beta-lactamase_2500,P62593,,YES,130,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-0.798,-0.798,,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.361275,0.000683376,0.493532 beta-lactamase_2500_N134N,beta-lactamase_2500_134,TEM-1,beta-lactamase_2500,P62593,,YES,134,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-0.879,-0.879,,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.361275,0.000644786,0.385288 beta-lactamase_2500_N152N,beta-lactamase_2500_152,TEM-1,beta-lactamase_2500,P62593,,YES,152,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-2.757,-2.757,,,0.863,H,A,0.61,0.92,2.061,,77.62,BPH,-2.97,0.361275,0.00471429,0.842789 beta-lactamase_2500_N168N,beta-lactamase_2500_168,TEM-1,beta-lactamase_2500,P62593,,YES,168,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-1.029,-1.029,,,0.113,G,A,0.61,-0.4,2.9,,44.41,HPA,-1.13233,0.361275,0.00288667,0.577451 beta-lactamase_2500_N173N,beta-lactamase_2500_173,TEM-1,beta-lactamase_2500,P62593,,YES,173,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-2.663,-2.663,,,1.044,T,l,0.61,1.25,1.88,,77.62,OPA,-1.46633,0.361275,0.0033769,0.821236 beta-lactamase_2500_N274N,beta-lactamase_2500_274,TEM-1,beta-lactamase_2500,P62593,,YES,274,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-2.082,-2.082,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.361275,0.0110418,0.596781 beta-lactamase_2500_N50N,beta-lactamase_2500_50,TEM-1,beta-lactamase_2500,P62593,,YES,50,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-2.979,-2.979,,,0.912,T,A,0.61,1.24,1.581,,77.62,HPP,-2.134,0.361275,0.0047211,0.828935 beta-lactamase_2500_N98N,beta-lactamase_2500_98,TEM-1,beta-lactamase_2500,P62593,,YES,98,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-2.973,-2.973,,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.361275,0.00505389,0.83784 beta-lactamase_2500_P105P,beta-lactamase_2500_105,TEM-1,beta-lactamase_2500,P62593,,YES,105,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.813,-0.813,,,0.226,T,A,0.52,0.8,3.1,,63.29,POH,-1.01533,0.361275,0.0011981,0.383855 beta-lactamase_2500_P143P,beta-lactamase_2500_143,TEM-1,beta-lactamase_2500,P62593,,YES,143,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.967,-0.967,,,0.075,H,A,0.52,-0.37,0.479,,66.78,OOB,-1.354,0.361275,0.00114551,0.470067 beta-lactamase_2500_P165P,beta-lactamase_2500_165,TEM-1,beta-lactamase_2500,P62593,,YES,165,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.373,-1.373,,,0.203,T,A,0.52,-0.31,0.414,,73.78,AOA,-1.359,0.361275,0.00549538,0.451542 beta-lactamase_2500_P172P,beta-lactamase_2500_172,TEM-1,beta-lactamase_2500,P62593,,YES,172,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.998,-0.998,,,0.639,T,b,0.52,0.24,4.99,,74.48,HOP,-2.03067,0.361275,0.00312594,0.658634 beta-lactamase_2500_P181P,beta-lactamase_2500_181,TEM-1,beta-lactamase_2500,P62593,,YES,181,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.813,-0.813,,,,H,A,0.52,-1.14,1.946,,61.54,HOH,-1.795,0.361275,0.000703122,0.470983 beta-lactamase_2500_P217P,beta-lactamase_2500_217,TEM-1,beta-lactamase_2500,P62593,,YES,217,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-2.062,-2.062,,,0.496,I,A,0.52,-0.33,0.431,,74.48,OOH,-1.64333,0.361275,0.00463211,0.532353 beta-lactamase_2500_P224P,beta-lactamase_2500_224,TEM-1,beta-lactamase_2500,P62593,,YES,224,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.893,-0.893,,,0.383,,B,0.52,-0.3,2.666,,74.48,HOH,-1.26433,0.361275,0.00189564,0.399502 beta-lactamase_2500_P250P,beta-lactamase_2500_250,TEM-1,beta-lactamase_2500,P62593,,YES,250,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-2.335,-2.335,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.361275,0.00550899,0.707767 beta-lactamase_2500_P255P,beta-lactamase_2500_255,TEM-1,beta-lactamase_2500,P62593,,YES,255,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-2.266,-2.266,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.361275,0.00499612,0.496572 beta-lactamase_2500_P25P,beta-lactamase_2500_25,TEM-1,beta-lactamase_2500,P62593,,YES,25,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.526,-1.526,,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.361275,0.00347571,0.618529 beta-lactamase_2500_P60P,beta-lactamase_2500_60,TEM-1,beta-lactamase_2500,P62593,,YES,60,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-2.469,-2.469,,,0.256,T,A,0.52,-0.56,1.581,,77.62,BOA,-1.97633,0.361275,0.00521318,0.48659 beta-lactamase_2500_P65P,beta-lactamase_2500_65,TEM-1,beta-lactamase_2500,P62593,,YES,65,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.894,-0.894,,,0.098,E,B,0.52,-0.62,0.3,,40.56,HOH,-1.03233,0.361275,0.00152776,0.43901 beta-lactamase_2500_Q203Q,beta-lactamase_2500_203,TEM-1,beta-lactamase_2500,P62593,,YES,203,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.168,-2.168,,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.361275,0.00631514,0.786775 beta-lactamase_2500_Q204Q,beta-lactamase_2500_204,TEM-1,beta-lactamase_2500,P62593,,YES,204,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-1.382,-1.382,,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.361275,0.00364106,0.649069 beta-lactamase_2500_Q267Q,beta-lactamase_2500_267,TEM-1,beta-lactamase_2500,P62593,,YES,267,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.308,-2.308,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.361275,0.0102128,0.752225 beta-lactamase_2500_Q276Q,beta-lactamase_2500_276,TEM-1,beta-lactamase_2500,P62593,,YES,276,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-1.144,-1.144,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.361275,0.0191712,0.638632 beta-lactamase_2500_Q37Q,beta-lactamase_2500_37,TEM-1,beta-lactamase_2500,P62593,,YES,37,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.134,-2.134,,,0.613,H,A,0.64,1.98,1.318,,73.08,APH,-2.06967,0.361275,0.00425833,0.837803 beta-lactamase_2500_Q86Q,beta-lactamase_2500_86,TEM-1,beta-lactamase_2500,P62593,,YES,86,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.4,-2.4,,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.361275,0.00450027,0.837279 beta-lactamase_2500_Q88Q,beta-lactamase_2500_88,TEM-1,beta-lactamase_2500,P62593,,YES,88,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.086,-2.086,,,0.807,,B,0.64,2.03,1.84,,77.62,APH,-1.53433,0.361275,0.00504167,0.834377 beta-lactamase_2500_Q97Q,beta-lactamase_2500_97,TEM-1,beta-lactamase_2500,P62593,,YES,97,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.072,-2.072,,,0.823,G,A,0.64,2.42,1.157,,77.62,PPP,-2.43833,0.361275,0.0045116,0.824711 beta-lactamase_2500_R118R,beta-lactamase_2500_118,TEM-1,beta-lactamase_2500,P62593,,YES,118,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.413,-2.413,,,0.457,H,A,1.2,1.39,2.144,,77.62,HBA,-1.785,0.361275,0.00538794,0.854936 beta-lactamase_2500_R159R,beta-lactamase_2500_159,TEM-1,beta-lactamase_2500,P62593,,YES,159,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-0.94,-0.94,,,0.316,,B,1.2,-0.55,2.341,,64.34,PBH,-1.011,0.361275,0.00108472,0.485862 beta-lactamase_2500_R162R,beta-lactamase_2500_162,TEM-1,beta-lactamase_2500,P62593,,YES,162,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.016,-1.016,,,0.124,S,B,1.2,-0.37,6.199,,64.69,ABH,-1.25,0.361275,0.000561334,0.50591 beta-lactamase_2500_R176R,beta-lactamase_2500_176,TEM-1,beta-lactamase_2500,P62593,,YES,176,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-0.863,-0.863,,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.361275,0.00105554,0.526878 beta-lactamase_2500_R189R,beta-lactamase_2500_189,TEM-1,beta-lactamase_2500,P62593,,YES,189,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.844,-1.844,,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.361275,0.0050699,0.812837 beta-lactamase_2500_R202R,beta-lactamase_2500_202,TEM-1,beta-lactamase_2500,P62593,,YES,202,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.292,-1.292,,,0.188,H,A,1.2,0.62,3.734,,77.62,PBP,-1.54767,0.361275,0.00321899,0.630944 beta-lactamase_2500_R220R,beta-lactamase_2500_220,TEM-1,beta-lactamase_2500,P62593,,YES,220,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-0.942,-0.942,,,0.295,I,A,1.2,-0.76,2.175,,74.48,HBP,-1.33633,0.361275,0.00232421,0.428855 beta-lactamase_2500_R239R,beta-lactamase_2500_239,TEM-1,beta-lactamase_2500,P62593,,YES,239,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-0.819,-0.819,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.361275,0.00213852,0.561831 beta-lactamase_2500_R242R,beta-lactamase_2500_242,TEM-1,beta-lactamase_2500,P62593,,YES,242,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.319,-1.319,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.361275,0.00452879,0.524733 beta-lactamase_2500_R257R,beta-lactamase_2500_257,TEM-1,beta-lactamase_2500,P62593,,YES,257,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.533,-1.533,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.361275,0.00756629,0.45144 beta-lactamase_2500_R273R,beta-lactamase_2500_273,TEM-1,beta-lactamase_2500,P62593,,YES,273,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.314,-2.314,,,0.564,H,A,1.2,1.57,19.943,19.943,73.78,ABP,-1.841,0.361275,0.0077952,0.766477 beta-lactamase_2500_R275R,beta-lactamase_2500_275,TEM-1,beta-lactamase_2500,P62593,,YES,275,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.397,-1.397,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.361275,0.0141984,0.511753 beta-lactamase_2500_R41R,beta-lactamase_2500_41,TEM-1,beta-lactamase_2500,P62593,,YES,41,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-0.942,-0.942,,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.361275,0.00123327,0.503425 beta-lactamase_2500_R59R,beta-lactamase_2500_59,TEM-1,beta-lactamase_2500,P62593,,YES,59,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.345,-1.345,,,0.329,S,L,1.2,-0.09,3.719,,73.08,HBO,-2.24267,0.361275,0.00318082,0.485327 beta-lactamase_2500_R63R,beta-lactamase_2500_63,TEM-1,beta-lactamase_2500,P62593,,YES,63,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-0.943,-0.943,,,0.218,,B,1.2,-0.31,0.929,,44.06,ABH,-0.992333,0.361275,0.00126938,0.457233 beta-lactamase_2500_R81R,beta-lactamase_2500_81,TEM-1,beta-lactamase_2500,P62593,,YES,81,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.466,-1.466,,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.361275,0.00499763,0.636178 beta-lactamase_2500_R91R,beta-lactamase_2500_91,TEM-1,beta-lactamase_2500,P62593,,YES,91,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.392,-1.392,,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.361275,0.00380226,0.520577 beta-lactamase_2500_R92R,beta-lactamase_2500_92,TEM-1,beta-lactamase_2500,P62593,,YES,92,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.718,-1.718,,,0.479,E,B,1.2,1.36,3.069,,65.38,BBH,-1.50367,0.361275,0.00429626,0.640669 beta-lactamase_2500_S104S,beta-lactamase_2500_104,TEM-1,beta-lactamase_2500,P62593,,YES,104,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.015,-1.015,,,0.04,,b,0.27,0.57,1.133,,63.29,HPO,-1.05267,0.361275,0.00218083,0.633477 beta-lactamase_2500_S122S,beta-lactamase_2500_122,TEM-1,beta-lactamase_2500,P62593,,YES,122,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.406,-2.406,,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.361275,0.00497825,0.81233 beta-lactamase_2500_S128S,beta-lactamase_2500_128,TEM-1,beta-lactamase_2500,P62593,,YES,128,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-0.84,-0.84,,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.361275,0.00071483,0.470669 beta-lactamase_2500_S201S,beta-lactamase_2500_201,TEM-1,beta-lactamase_2500,P62593,,YES,201,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.183,-1.183,,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.361275,0.00198815,0.679923 beta-lactamase_2500_S221S,beta-lactamase_2500_221,TEM-1,beta-lactamase_2500,P62593,,YES,221,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.754,-1.754,,,0.624,H,A,0.27,-0.2,1.971,,74.48,BPH,-1.59967,0.361275,0.0046094,0.789249 beta-lactamase_2500_S233S,beta-lactamase_2500_233,TEM-1,beta-lactamase_2500,P62593,,YES,233,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.886,-1.886,,,0.016,E,B,0.27,-1.01,2.851,,77.62,BPO,-1.17267,0.361275,0.00311415,0.637239 beta-lactamase_2500_S241S,beta-lactamase_2500_241,TEM-1,beta-lactamase_2500,P62593,,YES,241,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.433,-1.433,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.361275,0.00452736,0.59393 beta-lactamase_2500_S256S,beta-lactamase_2500_256,TEM-1,beta-lactamase_2500,P62593,,YES,256,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.621,-1.621,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.361275,0.00710634,0.553814 beta-lactamase_2500_S266S,beta-lactamase_2500_266,TEM-1,beta-lactamase_2500,P62593,,YES,266,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.369,-1.369,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.361275,0.0140785,0.569732 beta-lactamase_2500_S283S,beta-lactamase_2500_283,TEM-1,beta-lactamase_2500,P62593,,YES,283,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.638,-1.638,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.361275,0.0429138,0.690762 beta-lactamase_2500_S51S,beta-lactamase_2500_51,TEM-1,beta-lactamase_2500,P62593,,YES,51,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.526,-1.526,,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.361275,0.00504821,0.638959 beta-lactamase_2500_S57S,beta-lactamase_2500_57,TEM-1,beta-lactamase_2500,P62593,,YES,57,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.918,-1.918,,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.361275,0.00492804,0.659278 beta-lactamase_2500_S68S,beta-lactamase_2500_68,TEM-1,beta-lactamase_2500,P62593,,YES,68,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-0.913,-0.913,,,0.064,G,A,0.27,-1.03,2.824,,64.69,HPP,-1.37233,0.361275,0.000800065,0.431754 beta-lactamase_2500_S80S,beta-lactamase_2500_80,TEM-1,beta-lactamase_2500,P62593,,YES,80,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.029,-2.029,,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.361275,0.00565569,0.785071 beta-lactamase_2500_S96S,beta-lactamase_2500_96,TEM-1,beta-lactamase_2500,P62593,,YES,96,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.27,-2.27,,,0.368,,b,0.27,0.39,32.348,32.348,73.78,HPP,-2.019,0.361275,0.00551835,0.819729 beta-lactamase_2500_T107T,beta-lactamase_2500_107,TEM-1,beta-lactamase_2500,P62593,,YES,107,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.117,-1.117,,,,G,A,0.22,-0.06,2.686,,67.83,HPA,-1.265,0.361275,0.00239347,0.666639 beta-lactamase_2500_T112T,beta-lactamase_2500_112,TEM-1,beta-lactamase_2500,P62593,,YES,112,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.186,-2.186,,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.361275,0.00531334,0.839732 beta-lactamase_2500_T116T,beta-lactamase_2500_116,TEM-1,beta-lactamase_2500,P62593,,YES,116,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.28,-1.28,,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.361275,0.00336175,0.657435 beta-lactamase_2500_T126T,beta-lactamase_2500_126,TEM-1,beta-lactamase_2500,P62593,,YES,126,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.122,-1.122,,,0.05,H,A,0.22,-0.05,0.817,,44.41,HPH,-1.60467,0.361275,0.00244552,0.683049 beta-lactamase_2500_T131T,beta-lactamase_2500_131,TEM-1,beta-lactamase_2500,P62593,,YES,131,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.328,-1.328,,,,H,A,0.22,-0.69,3.048,,67.48,PPH,-1.00867,0.361275,0.00345886,0.695712 beta-lactamase_2500_T138T,beta-lactamase_2500_138,TEM-1,beta-lactamase_2500,P62593,,YES,138,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.506,-2.506,,,0.662,H,A,0.22,-0.03,30.445,30.445,73.78,HPP,-1.81233,0.361275,0.00487868,0.845328 beta-lactamase_2500_T139T,beta-lactamase_2500_139,TEM-1,beta-lactamase_2500,P62593,,YES,139,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.901,-1.901,,,0.216,H,A,0.22,0.39,2.256,,77.62,PPH,-2.04667,0.361275,0.00441837,0.750295 beta-lactamase_2500_T147T,beta-lactamase_2500_147,TEM-1,beta-lactamase_2500,P62593,,YES,147,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.149,-1.149,,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.361275,0.00226017,0.523439 beta-lactamase_2500_T158T,beta-lactamase_2500_158,TEM-1,beta-lactamase_2500,P62593,,YES,158,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.116,-1.116,,,0.036,,B,0.22,-0.85,1.344,,69.58,HPB,-1.269,0.361275,0.00341825,0.647432 beta-lactamase_2500_T178T,beta-lactamase_2500_178,TEM-1,beta-lactamase_2500,P62593,,YES,178,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-0.791,-0.791,,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.361275,0.000684366,0.528444 beta-lactamase_2500_T179T,beta-lactamase_2500_179,TEM-1,beta-lactamase_2500,P62593,,YES,179,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.085,-1.085,,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.361275,0.00226045,0.592087 beta-lactamase_2500_T186T,beta-lactamase_2500_186,TEM-1,beta-lactamase_2500,P62593,,YES,186,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.522,-2.522,,,0.396,H,A,0.22,-0.28,2.144,,77.62,HPP,-1.77633,0.361275,0.00485034,0.841638 beta-lactamase_2500_T187T,beta-lactamase_2500_187,TEM-1,beta-lactamase_2500,P62593,,YES,187,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.401,-1.401,,,0.007,H,A,0.22,-1.19,3.91,,67.48,PPH,-1.69633,0.361275,0.00491782,0.665706 beta-lactamase_2500_T193T,beta-lactamase_2500_193,TEM-1,beta-lactamase_2500,P62593,,YES,193,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.914,-1.914,,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.361275,0.00482669,0.792621 beta-lactamase_2500_T198T,beta-lactamase_2500_198,TEM-1,beta-lactamase_2500,P62593,,YES,198,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.168,-2.168,,,0.489,,B,0.22,-0.13,0.37,,73.78,HPH,-1.98767,0.361275,0.004311,0.724132 beta-lactamase_2500_T263T,beta-lactamase_2500_263,TEM-1,beta-lactamase_2500,P62593,,YES,263,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.031,-2.031,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.361275,0.0110582,0.751007 beta-lactamase_2500_T264T,beta-lactamase_2500_264,TEM-1,beta-lactamase_2500,P62593,,YES,264,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.985,-1.985,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.361275,0.0119399,0.660457 beta-lactamase_2500_T269T,beta-lactamase_2500_269,TEM-1,beta-lactamase_2500,P62593,,YES,269,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.156,-2.156,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.361275,0.00950944,0.773842 beta-lactamase_2500_T27T,beta-lactamase_2500_27,TEM-1,beta-lactamase_2500,P62593,,YES,27,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.905,-1.905,,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.361275,0.00306559,0.63408 beta-lactamase_2500_T69T,beta-lactamase_2500_69,TEM-1,beta-lactamase_2500,P62593,,YES,69,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-0.973,-0.973,,,,G,A,0.22,-1.24,2.05,,93.01,PPH,-1.01833,0.361275,0.00127498,0.485354 beta-lactamase_2500_V101V,beta-lactamase_2500_101,TEM-1,beta-lactamase_2500,P62593,,YES,101,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.295,-1.295,,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.361275,0.00374492,0.586482 beta-lactamase_2500_V106V,beta-lactamase_2500_106,TEM-1,beta-lactamase_2500,P62593,,YES,106,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.218,-1.218,,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.361275,0.00304168,0.624386 beta-lactamase_2500_V117V,beta-lactamase_2500_117,TEM-1,beta-lactamase_2500,P62593,,YES,117,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.53,-1.53,,,,H,A,0.44,-0.34,1.23,,65.03,PHB,-1.741,0.361275,0.00467906,0.599585 beta-lactamase_2500_V157V,beta-lactamase_2500_157,TEM-1,beta-lactamase_2500,P62593,,YES,157,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.751,-1.751,,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.361275,0.00506849,0.810152 beta-lactamase_2500_V214V,beta-lactamase_2500_214,TEM-1,beta-lactamase_2500,P62593,,YES,214,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.299,-1.299,,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.361275,0.00628442,0.556757 beta-lactamase_2500_V259V,beta-lactamase_2500_259,TEM-1,beta-lactamase_2500,P62593,,YES,259,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.522,-1.522,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.361275,0.0070773,0.603412 beta-lactamase_2500_V260V,beta-lactamase_2500_260,TEM-1,beta-lactamase_2500,P62593,,YES,260,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.101,-1.101,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.361275,0.00471757,0.544942 beta-lactamase_2500_V29V,beta-lactamase_2500_29,TEM-1,beta-lactamase_2500,P62593,,YES,29,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-2.856,-2.856,,,0.733,H,A,0.44,-0.78,1.931,,93.01,HHB,-2.24733,0.361275,0.00318969,0.83405 beta-lactamase_2500_V31V,beta-lactamase_2500_31,TEM-1,beta-lactamase_2500,P62593,,YES,31,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.822,-1.822,,,,H,A,0.44,-0.46,0.955,,73.78,BHB,-2.03767,0.361275,0.00478065,0.586274 beta-lactamase_2500_V42V,beta-lactamase_2500_42,TEM-1,beta-lactamase_2500,P62593,,YES,42,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.564,-1.564,,,0.017,E,B,0.44,-0.51,1.86,,63.99,BHO,-1.042,0.361275,0.00404515,0.575179 beta-lactamase_2500_V72V,beta-lactamase_2500_72,TEM-1,beta-lactamase_2500,P62593,,YES,72,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.658,-1.658,,,,H,A,0.44,-1.03,2.079,,65.73,BHH,-1.32167,0.361275,0.00501194,0.626812 beta-lactamase_2500_V78V,beta-lactamase_2500_78,TEM-1,beta-lactamase_2500,P62593,,YES,78,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.459,-1.459,,,,H,A,0.44,-0.47,31.376,31.376,63.64,HHH,-1.17833,0.361275,0.00492501,0.631145 beta-lactamase_2500_V82V,beta-lactamase_2500_82,TEM-1,beta-lactamase_2500,P62593,,YES,82,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.325,-1.325,,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.361275,0.00397046,0.593778 beta-lactamase_2500_W163W,beta-lactamase_2500_163,TEM-1,beta-lactamase_2500,P62593,,YES,163,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-1.843,-1.843,,,0.467,,B,0.47,-0.5,32.624,32.624,63.99,BHA,-1.269,0.361275,0.00418955,0.75309 beta-lactamase_2500_W208W,beta-lactamase_2500_208,TEM-1,beta-lactamase_2500,P62593,,YES,208,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-0.818,-0.818,,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.361275,0.00126609,0.463568 beta-lactamase_2500_W227W,beta-lactamase_2500_227,TEM-1,beta-lactamase_2500,P62593,,YES,227,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-0.982,-0.982,,,0.272,,B,0.47,-0.29,1.37,,74.48,OHH,-1.595,0.361275,0.00226019,0.335135 beta-lactamase_2500_W288W,beta-lactamase_2500_288,TEM-1,beta-lactamase_2500,P62593,,YES,288,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,,,,,,,,,,,,,BHO,,0.361275,,0.447462 beta-lactamase_2500_Y103Y,beta-lactamase_2500_103,TEM-1,beta-lactamase_2500,P62593,,YES,103,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-1.33,-1.33,,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.361275,0.00443048,0.543955 beta-lactamase_2500_Y262Y,beta-lactamase_2500_262,TEM-1,beta-lactamase_2500,P62593,,YES,262,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-1.332,-1.332,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.361275,0.00853516,0.519187 beta-lactamase_2500_Y44Y,beta-lactamase_2500_44,TEM-1,beta-lactamase_2500,P62593,,YES,44,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-2.547,-2.547,,,,E,B,0.21,-0.45,2.184,,73.78,OHH,-1.86267,0.361275,0.00426364,0.441252 beta-lactamase_2500_Y95Y,beta-lactamase_2500_95,TEM-1,beta-lactamase_2500,P62593,,YES,95,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-1.715,-1.715,,,0.122,,b,0.21,-0.37,2.914,,77.62,BHP,-2.16167,0.361275,0.00479449,0.477319 beta-lactamase_39_A123A,beta-lactamase_39_123,TEM-1,beta-lactamase_39,P62593,,YES,123,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.834,-0.834,,,0.039,H,A,0.46,-0.72,0.705,,41.26,PHH,-1.47367,0.0495842,0.0010157,0.802779 beta-lactamase_39_A124A,beta-lactamase_39_124,TEM-1,beta-lactamase_39,P62593,,YES,124,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.181,-1.181,,,,H,A,0.46,-0.9,1.367,,64.34,HHH,-1.152,0.0495842,0.00481399,0.876518 beta-lactamase_39_A132A,beta-lactamase_39_132,TEM-1,beta-lactamase_39,P62593,,YES,132,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.9,-0.9,,,,H,A,0.46,-0.93,8.408,,64.69,PHH,-1.138,0.0495842,0.000962524,0.773561 beta-lactamase_39_A133A,beta-lactamase_39_133,TEM-1,beta-lactamase_39,P62593,,YES,133,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.186,-1.186,,,,H,A,0.46,-0.86,0.373,,67.83,HHP,-0.988333,0.0495842,0.00468022,0.839078 beta-lactamase_39_A148A,beta-lactamase_39_148,TEM-1,beta-lactamase_39,P62593,,YES,148,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.757,-1.757,,,0.379,H,A,0.46,-0.55,3.551,,72.73,PHH,-1.40167,0.0495842,0.00547053,0.943243 beta-lactamase_39_A170A,beta-lactamase_39_170,TEM-1,beta-lactamase_39,P62593,,YES,170,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.237,-1.237,,,0.126,,L,0.46,-0.35,3.7,,64.69,AHH,-1.63267,0.0495842,0.00431903,0.911711 beta-lactamase_39_A182A,beta-lactamase_39_182,TEM-1,beta-lactamase_39,P62593,,YES,182,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.777,-1.777,,,0.136,H,A,0.46,-0.66,2.598,,93.01,OHH,-1.27367,0.0495842,0.00559099,0.936998 beta-lactamase_39_A183A,beta-lactamase_39_183,TEM-1,beta-lactamase_39,P62593,,YES,183,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.231,-1.231,,,0.155,H,A,0.46,-0.91,1.237,,77.62,HHH,-1.53367,0.0495842,0.00296631,0.904226 beta-lactamase_39_A185A,beta-lactamase_39_185,TEM-1,beta-lactamase_39,P62593,,YES,185,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.406,-1.406,,,,H,A,0.46,-1.02,2.68,,65.03,HHP,-1.84033,0.0495842,0.00467449,0.909505 beta-lactamase_39_A200A,beta-lactamase_39_200,TEM-1,beta-lactamase_39,P62593,,YES,200,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.878,-1.878,,,0.757,H,A,0.46,-0.19,1.54,,77.62,HHP,-2.001,0.0495842,0.0060056,0.942902 beta-lactamase_39_A211A,beta-lactamase_39_211,TEM-1,beta-lactamase_39,P62593,,YES,211,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.896,-1.896,,,0.369,T,A,0.46,-0.69,1.419,,77.62,AHA,-1.94633,0.0495842,0.00648183,0.94079 beta-lactamase_39_A215A,beta-lactamase_39_215,TEM-1,beta-lactamase_39,P62593,,YES,215,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.503,-1.503,,,,,a,0.46,-0.93,0.494,,74.48,HHO,-1.42633,0.0495842,0.00544007,0.869169 beta-lactamase_39_A222A,beta-lactamase_39_222,TEM-1,beta-lactamase_39,P62593,,YES,222,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.103,-2.103,,,0.233,H,A,0.46,-0.25,1.448,,77.62,PHH,-1.63733,0.0495842,0.00466094,0.926743 beta-lactamase_39_A225A,beta-lactamase_39_225,TEM-1,beta-lactamase_39,P62593,,YES,225,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.845,-1.845,,,1,T,B,0.46,-0.38,9.874,9.874,74.48,OHO,-1.39967,0.0495842,0.00465057,0.922467 beta-lactamase_39_A230A,beta-lactamase_39_230,TEM-1,beta-lactamase_39,P62593,,YES,230,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.154,-1.154,,,0.01,E,B,0.46,-1.17,1.171,,50,HHA,-1.079,0.0495842,0.00516841,0.864386 beta-lactamase_39_A235A,beta-lactamase_39_235,TEM-1,beta-lactamase_39,P62593,,YES,235,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.266,-1.266,,,0.32,E,B,0.46,-0.86,1.344,,50,OHO,-0.89,0.0495842,0.00493474,0.886406 beta-lactamase_39_A246A,beta-lactamase_39_246,TEM-1,beta-lactamase_39,P62593,,YES,246,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.121,-2.121,,,0.01,E,B,0.46,-1.01,1.331,,73.78,HHH,-1.55633,0.0495842,0.00569458,0.850921 beta-lactamase_39_A247A,beta-lactamase_39_247,TEM-1,beta-lactamase_39,P62593,,YES,247,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.48,-1.48,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.0495842,0.00611275,0.920876 beta-lactamase_39_A268A,beta-lactamase_39_268,TEM-1,beta-lactamase_39,P62593,,YES,268,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.023,-2.023,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.0495842,0.0102525,0.947081 beta-lactamase_39_A278A,beta-lactamase_39_278,TEM-1,beta-lactamase_39,P62593,,YES,278,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.348,-1.348,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.0495842,0.0310297,0.912802 beta-lactamase_39_A282A,beta-lactamase_39_282,TEM-1,beta-lactamase_39,P62593,,YES,282,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.586,-1.586,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.0495842,0.0449821,0.924742 beta-lactamase_39_A34A,beta-lactamase_39_34,TEM-1,beta-lactamase_39,P62593,,YES,34,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.059,-2.059,,,,H,A,0.46,-0.54,13.292,13.292,73.78,AHA,-1.74967,0.0495842,0.00407913,0.925397 beta-lactamase_39_A40A,beta-lactamase_39_40,TEM-1,beta-lactamase_39,P62593,,YES,40,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.402,-1.402,,,0.155,S,B,0.46,0.21,0.783,,73.78,OHB,-1.40267,0.0495842,0.00490026,0.921049 beta-lactamase_39_A77A,beta-lactamase_39_77,TEM-1,beta-lactamase_39,P62593,,YES,77,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.234,-1.234,,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.0495842,0.00282362,0.909357 beta-lactamase_39_A84A,beta-lactamase_39_84,TEM-1,beta-lactamase_39,P62593,,YES,84,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.651,-1.651,,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.0495842,0.00503822,0.951909 beta-lactamase_39_C121C,beta-lactamase_39_121,TEM-1,beta-lactamase_39,P62593,,YES,121,C,C,CC,Special,Special,5.07,5.07,0,0,121,121,0,108.5,108.5,0,-0.953,-0.953,,,,H,A,0.46,-0.81,7.644,,63.29,HOP,-1.46767,0.0495842,0.000744322,0.83771 beta-lactamase_39_C75C,beta-lactamase_39_75,TEM-1,beta-lactamase_39,P62593,,YES,75,C,C,CC,Special,Special,5.07,5.07,0,0,121,121,0,108.5,108.5,0,-1.245,-1.245,,,,H,A,0.46,-0.87,2.369,,50,HOO,-1.24333,0.0495842,0.0034616,0.913538 beta-lactamase_39_D113D,beta-lactamase_39_113,TEM-1,beta-lactamase_39,P62593,,YES,113,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.829,-1.829,,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.0495842,0.00474112,0.900404 beta-lactamase_39_D129D,beta-lactamase_39_129,TEM-1,beta-lactamase_39,P62593,,YES,129,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.816,-0.816,,,,,B,0.75,-0.69,0.56,,34.97,PAP,-0.818,0.0495842,0.00109178,0.539362 beta-lactamase_39_D155D,beta-lactamase_39_155,TEM-1,beta-lactamase_39,P62593,,YES,155,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.889,-0.889,,,0.049,,B,0.75,-0.9,3.208,,64.69,OAB,-1.62267,0.0495842,0.00135315,0.738159 beta-lactamase_39_D161D,beta-lactamase_39_161,TEM-1,beta-lactamase_39,P62593,,YES,161,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.891,-0.891,,,0.341,,A,0.75,-0.52,1.602,,61.19,HAB,-0.961333,0.0495842,0.000897697,0.89262 beta-lactamase_39_D174D,beta-lactamase_39_174,TEM-1,beta-lactamase_39,P62593,,YES,174,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.738,-0.738,,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.0495842,0.00125633,0.918298 beta-lactamase_39_D177D,beta-lactamase_39_177,TEM-1,beta-lactamase_39,P62593,,YES,177,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.967,-0.967,,,0.006,T,L,0.75,-1.02,3.536,,64.69,BAP,-0.873667,0.0495842,0.000864022,0.693383 beta-lactamase_39_D207D,beta-lactamase_39_207,TEM-1,beta-lactamase_39,P62593,,YES,207,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.064,-2.064,,,0.409,H,A,0.75,0.12,14.511,14.511,77.62,HAH,-1.77033,0.0495842,0.00592942,0.92625 beta-lactamase_39_D212D,beta-lactamase_39_212,TEM-1,beta-lactamase_39,P62593,,YES,212,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.624,-1.624,,,0.037,,b,0.75,-0.58,10.748,10.748,74.48,HAB,-1.77667,0.0495842,0.00644302,0.829651 beta-lactamase_39_D231D,beta-lactamase_39_231,TEM-1,beta-lactamase_39,P62593,,YES,231,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.816,-0.816,,,,E,B,0.75,-1.06,0.462,,65.38,HAB,-0.994,0.0495842,0.00107395,0.649185 beta-lactamase_39_D252D,beta-lactamase_39_252,TEM-1,beta-lactamase_39,P62593,,YES,252,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.94,-1.94,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.0495842,0.00575769,0.933682 beta-lactamase_39_D271D,beta-lactamase_39_271,TEM-1,beta-lactamase_39,P62593,,YES,271,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.249,-1.249,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.0495842,0.00752082,0.827147 beta-lactamase_39_D33D,beta-lactamase_39_33,TEM-1,beta-lactamase_39,P62593,,YES,33,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.321,-2.321,,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.0495842,0.00435556,0.917335 beta-lactamase_39_D36D,beta-lactamase_39_36,TEM-1,beta-lactamase_39,P62593,,YES,36,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.732,-2.732,,,0.555,H,A,0.75,1.17,13.689,13.689,77.62,AAP,-1.91167,0.0495842,0.00476483,0.904416 beta-lactamase_39_D48D,beta-lactamase_39_48,TEM-1,beta-lactamase_39,P62593,,YES,48,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.101,-1.101,,,0.189,E,B,0.75,0.21,0.735,,50.35,HAH,-1.62467,0.0495842,0.0027273,0.884354 beta-lactamase_39_D83D,beta-lactamase_39_83,TEM-1,beta-lactamase_39,P62593,,YES,83,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.066,-1.066,,,0.354,H,A,0.75,0.22,0.752,,48.95,HAH,-1.34733,0.0495842,0.00205968,0.885432 beta-lactamase_39_D99D,beta-lactamase_39_99,TEM-1,beta-lactamase_39,P62593,,YES,99,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.191,-1.191,,,0.402,G,A,0.75,0.36,0.374,,64.69,PAH,-1.794,0.0495842,0.00305446,0.933749 beta-lactamase_39_E102E,beta-lactamase_39_102,TEM-1,beta-lactamase_39,P62593,,YES,102,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.118,-2.118,,,0.722,S,B,1.04,1.82,3.87,,73.08,HAH,-1.581,0.0495842,0.00486633,0.938521 beta-lactamase_39_E108E,beta-lactamase_39_108,TEM-1,beta-lactamase_39,P62593,,YES,108,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.46,-1.46,,,0.572,G,A,1.04,1.87,20.151,20.151,72.73,PAB,-1.437,0.0495842,0.00413372,0.949604 beta-lactamase_39_E119E,beta-lactamase_39_119,TEM-1,beta-lactamase_39,P62593,,YES,119,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.412,-1.412,,,0.358,H,A,1.04,0.51,1.341,,63.99,BAH,-1.623,0.0495842,0.00386966,0.917936 beta-lactamase_39_E145E,beta-lactamase_39_145,TEM-1,beta-lactamase_39,P62593,,YES,145,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.357,-2.357,,,0.545,H,A,1.04,0.79,1.199,,77.62,BAH,-2.069,0.0495842,0.00553285,0.947434 beta-lactamase_39_E164E,beta-lactamase_39_164,TEM-1,beta-lactamase_39,P62593,,YES,164,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-0.948,-0.948,,,0.011,T,B,1.04,-0.4,0.664,,64.69,HAO,-1.388,0.0495842,0.00137286,0.415866 beta-lactamase_39_E166E,beta-lactamase_39_166,TEM-1,beta-lactamase_39,P62593,,YES,166,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.756,-1.756,,,0.508,G,A,1.04,1.05,17.227,17.227,73.08,OAH,-1.42233,0.0495842,0.00512989,0.946703 beta-lactamase_39_E169E,beta-lactamase_39_169,TEM-1,beta-lactamase_39,P62593,,YES,169,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.23,-1.23,,,0.337,,A,1.04,1,15.633,15.633,73.08,PAH,-1.16533,0.0495842,0.00400994,0.914059 beta-lactamase_39_E175E,beta-lactamase_39_175,TEM-1,beta-lactamase_39,P62593,,YES,175,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.336,-2.336,,,0.551,,A,1.04,1.05,3.676,,77.62,AAB,-1.31233,0.0495842,0.00482205,0.933636 beta-lactamase_39_E195E,beta-lactamase_39_195,TEM-1,beta-lactamase_39,P62593,,YES,195,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.186,-2.186,,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.0495842,0.00496565,0.921971 beta-lactamase_39_E210E,beta-lactamase_39_210,TEM-1,beta-lactamase_39,P62593,,YES,210,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.319,-2.319,,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.0495842,0.00663582,0.95137 beta-lactamase_39_E238E,beta-lactamase_39_238,TEM-1,beta-lactamase_39,P62593,,YES,238,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.002,-2.002,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.0495842,0.00743256,0.917714 beta-lactamase_39_E26E,beta-lactamase_39_26,TEM-1,beta-lactamase_39,P62593,,YES,26,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.454,-2.454,,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.0495842,0.00297948,0.942191 beta-lactamase_39_E272E,beta-lactamase_39_272,TEM-1,beta-lactamase_39,P62593,,YES,272,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.127,-1.127,,,0.081,H,A,0.43,-0.97,12.983,12.983,63.64,AAB,-1.56333,0.0495842,0.00545371,0.851027 beta-lactamase_39_E279E,beta-lactamase_39_279,TEM-1,beta-lactamase_39,P62593,,YES,279,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.038,-1.038,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.0495842,0.0192826,0.852527 beta-lactamase_39_E35E,beta-lactamase_39_35,TEM-1,beta-lactamase_39,P62593,,YES,35,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-0.869,-0.869,,,0.15,H,A,1.04,0.21,1.081,,46.85,HAA,-1.88667,0.0495842,0.00174441,0.888188 beta-lactamase_39_E46E,beta-lactamase_39_46,TEM-1,beta-lactamase_39,P62593,,YES,46,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.94,-1.94,,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.0495842,0.00427568,0.865445 beta-lactamase_39_E56E,beta-lactamase_39_56,TEM-1,beta-lactamase_39,P62593,,YES,56,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.043,-2.043,,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.0495842,0.00238534,0.90136 beta-lactamase_39_E61E,beta-lactamase_39_61,TEM-1,beta-lactamase_39,P62593,,YES,61,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.115,-2.115,,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.0495842,0.00440955,0.918544 beta-lactamase_39_E62E,beta-lactamase_39_62,TEM-1,beta-lactamase_39,P62593,,YES,62,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.193,-1.193,,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.0495842,0.00264802,0.912319 beta-lactamase_39_E87E,beta-lactamase_39_87,TEM-1,beta-lactamase_39,P62593,,YES,87,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.421,-1.421,,,0.048,,B,1.04,0.92,15.231,15.231,64.69,PAP,-1.969,0.0495842,0.00337888,0.902098 beta-lactamase_39_F149F,beta-lactamase_39_149,TEM-1,beta-lactamase_39,P62593,,YES,149,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.299,-1.299,,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.0495842,0.00418462,0.950645 beta-lactamase_39_F228F,beta-lactamase_39_228,TEM-1,beta-lactamase_39,P62593,,YES,228,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-2.342,-2.342,,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.0495842,0.0046669,0.931236 beta-lactamase_39_F58F,beta-lactamase_39_58,TEM-1,beta-lactamase_39,P62593,,YES,58,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-2.914,-2.914,,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.0495842,0.00523369,0.935375 beta-lactamase_39_F64F,beta-lactamase_39_64,TEM-1,beta-lactamase_39,P62593,,YES,64,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-0.841,-0.841,,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.0495842,0.000947691,0.757631 beta-lactamase_39_F70F,beta-lactamase_39_70,TEM-1,beta-lactamase_39,P62593,,YES,70,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.169,-1.169,,,,H,A,0.58,-1.34,1.14,,63.99,PHB,-0.980667,0.0495842,0.00193499,0.863694 beta-lactamase_39_G114G,beta-lactamase_39_114,TEM-1,beta-lactamase_39,P62593,,YES,114,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.094,-1.094,,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.0495842,0.00224919,0.893437 beta-lactamase_39_G141G,beta-lactamase_39_141,TEM-1,beta-lactamase_39,P62593,,YES,141,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.828,-0.828,,,0.575,T,l,0.29,-0.28,0.722,,64.69,HOO,-1.08933,0.0495842,0.0012419,0.921072 beta-lactamase_39_G142G,beta-lactamase_39_142,TEM-1,beta-lactamase_39,P62593,,YES,142,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.707,-0.707,,,0.034,,p,0.29,-0.64,1.947,,64.69,OOO,-0.834,0.0495842,0.00060149,0.869383 beta-lactamase_39_G154G,beta-lactamase_39_154,TEM-1,beta-lactamase_39,P62593,,YES,154,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.823,-0.823,,,0.54,T,l,0.29,-0.56,1.151,,64.69,HOA,-1.635,0.0495842,0.00180205,0.905097 beta-lactamase_39_G194G,beta-lactamase_39_194,TEM-1,beta-lactamase_39,P62593,,YES,194,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.396,-1.396,,,0.276,S,b,0.29,0.36,4.852,,67.83,POA,-1.832,0.0495842,0.00392163,0.947605 beta-lactamase_39_G216G,beta-lactamase_39_216,TEM-1,beta-lactamase_39,P62593,,YES,216,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.477,-1.477,,,0.437,I,A,0.29,-0.58,0.834,,74.48,HOO,-1.68067,0.0495842,0.00639568,0.927464 beta-lactamase_39_G226G,beta-lactamase_39_226,TEM-1,beta-lactamase_39,P62593,,YES,226,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.461,-1.461,,,0.701,T,l,0.29,-0.25,23.034,23.034,74.48,HOH,-1.42933,0.0495842,0.00665294,0.945907 beta-lactamase_39_G234G,beta-lactamase_39_234,TEM-1,beta-lactamase_39,P62593,,YES,234,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.62,-0.62,,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.0495842,0.000889577,0.80901 beta-lactamase_39_G236G,beta-lactamase_39_236,TEM-1,beta-lactamase_39,P62593,,YES,236,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.784,-0.784,,,0.241,,b,0.29,-0.59,1.883,,64.69,HOO,-1.025,0.0495842,0.00162372,0.912609 beta-lactamase_39_G240G,beta-lactamase_39_240,TEM-1,beta-lactamase_39,P62593,,YES,240,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.537,-1.537,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.0495842,0.00591201,0.937847 beta-lactamase_39_G243G,beta-lactamase_39_243,TEM-1,beta-lactamase_39,P62593,,YES,243,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.532,-1.532,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.0495842,0.00464034,0.863989 beta-lactamase_39_G249G,beta-lactamase_39_249,TEM-1,beta-lactamase_39,P62593,,YES,249,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.312,-1.312,,,0.256,S,B,0.23,0.04,30.841,30.841,72.73,HOO,-1.81367,0.0495842,0.00220169,0.941316 beta-lactamase_39_G253G,beta-lactamase_39_253,TEM-1,beta-lactamase_39,P62593,,YES,253,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-2.253,-2.253,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.0495842,0.00786358,0.934625 beta-lactamase_39_G265G,beta-lactamase_39_265,TEM-1,beta-lactamase_39,P62593,,YES,265,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-2.58,-2.58,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.0495842,0.00811926,0.954023 beta-lactamase_39_G281G,beta-lactamase_39_281,TEM-1,beta-lactamase_39,P62593,,YES,281,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-2.247,-2.247,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.0495842,0.0406482,0.931892 beta-lactamase_39_G39G,beta-lactamase_39_39,TEM-1,beta-lactamase_39,P62593,,YES,39,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.864,-1.864,,,0.701,T,L,0.29,0.47,1.454,,77.62,HOH,-1.53633,0.0495842,0.00487611,0.929352 beta-lactamase_39_G43G,beta-lactamase_39_43,TEM-1,beta-lactamase_39,P62593,,YES,43,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.62,-0.62,,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.0495842,0.00120151,0.792756 beta-lactamase_39_G52G,beta-lactamase_39_52,TEM-1,beta-lactamase_39,P62593,,YES,52,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.149,-1.149,,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.0495842,0.00340138,0.912175 beta-lactamase_39_G76G,beta-lactamase_39_76,TEM-1,beta-lactamase_39,P62593,,YES,76,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.189,-1.189,,,,H,A,0.29,-0.67,2.145,,67.83,OOH,-1.22267,0.0495842,0.00476637,0.901434 beta-lactamase_39_G85G,beta-lactamase_39_85,TEM-1,beta-lactamase_39,P62593,,YES,85,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.011,-1.011,,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.0495842,0.00252173,0.916558 beta-lactamase_39_G90G,beta-lactamase_39_90,TEM-1,beta-lactamase_39,P62593,,YES,90,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-2.091,-2.091,,,0.598,T,A,0.29,0.32,30.794,30.794,77.62,HOB,-1.52633,0.0495842,0.00490273,0.944649 beta-lactamase_39_H110H,beta-lactamase_39_110,TEM-1,beta-lactamase_39,P62593,,YES,110,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-1.706,-1.706,,,0.341,G,a,0.17,1.08,4.071,,64.69,BBH,-1.73333,0.0495842,0.00441499,0.970707 beta-lactamase_39_H151H,beta-lactamase_39_151,TEM-1,beta-lactamase_39,P62593,,YES,151,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-2.96,-2.96,,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.0495842,0.00216946,0.940607 beta-lactamase_39_H156H,beta-lactamase_39_156,TEM-1,beta-lactamase_39,P62593,,YES,156,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-3.156,-3.156,,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.0495842,0.00468596,0.934484 beta-lactamase_39_H24H,beta-lactamase_39_24,TEM-1,beta-lactamase_39,P62593,,YES,24,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-2.481,-2.481,,,,,,,,2.708,,93.01,OBO,-2.0035,0.0495842,0.00238894,0.90093 beta-lactamase_39_H287H,beta-lactamase_39_287,TEM-1,beta-lactamase_39,P62593,,YES,287,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,,,,,,,,,,,,,BBH,-1.111,0.0495842,,0.909947 beta-lactamase_39_H94H,beta-lactamase_39_94,TEM-1,beta-lactamase_39,P62593,,YES,94,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-2.5,-2.5,,,0.776,,B,0.17,1.24,11.583,11.583,77.62,HBH,-1.872,0.0495842,0.00389226,0.93424 beta-lactamase_39_I125I,beta-lactamase_39_125,TEM-1,beta-lactamase_39,P62593,,YES,125,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.441,-1.441,,,,H,A,0.48,-0.7,0.503,,63.29,HHP,-1.248,0.0495842,0.00383964,0.874718 beta-lactamase_39_I140I,beta-lactamase_39_140,TEM-1,beta-lactamase_39,P62593,,YES,140,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.733,-1.733,,,0.128,H,A,0.48,0.41,1.16,,73.08,PHO,-1.48733,0.0495842,0.00597777,0.941975 beta-lactamase_39_I171I,beta-lactamase_39_171,TEM-1,beta-lactamase_39,P62593,,YES,171,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-2.431,-2.431,,,0.361,,B,0.48,0.53,16.954,16.954,77.62,HHO,-1.55533,0.0495842,0.00623355,0.966836 beta-lactamase_39_I206I,beta-lactamase_39_206,TEM-1,beta-lactamase_39,P62593,,YES,206,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-2.429,-2.429,,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.0495842,0.00528934,0.931059 beta-lactamase_39_I229I,beta-lactamase_39_229,TEM-1,beta-lactamase_39,P62593,,YES,229,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.267,-1.267,,,0.083,E,B,0.48,-0.76,1.114,,50,HHH,-1.58767,0.0495842,0.00477249,0.882625 beta-lactamase_39_I244I,beta-lactamase_39_244,TEM-1,beta-lactamase_39,P62593,,YES,244,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.555,-1.555,,,,E,B,0.48,-0.84,1.325,,77.62,OHH,-1.385,0.0495842,0.00605379,0.856358 beta-lactamase_39_I245I,beta-lactamase_39_245,TEM-1,beta-lactamase_39,P62593,,YES,245,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.068,-1.068,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.0495842,0.00391032,0.868567 beta-lactamase_39_I258I,beta-lactamase_39_258,TEM-1,beta-lactamase_39,P62593,,YES,258,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.975,-1.975,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.0495842,0.007931,0.867422 beta-lactamase_39_I261I,beta-lactamase_39_261,TEM-1,beta-lactamase_39,P62593,,YES,261,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-2.88,-2.88,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.0495842,0.0123091,0.879835 beta-lactamase_39_I277I,beta-lactamase_39_277,TEM-1,beta-lactamase_39,P62593,,YES,277,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.869,-1.869,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.0495842,0.0169305,0.931896 beta-lactamase_39_I280I,beta-lactamase_39_280,TEM-1,beta-lactamase_39,P62593,,YES,280,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.708,-1.708,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.0495842,0.0530888,0.902103 beta-lactamase_39_I285I,beta-lactamase_39_285,TEM-1,beta-lactamase_39,P62593,,YES,285,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.845,-1.845,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.0495842,0.101555,0.97506 beta-lactamase_39_I45I,beta-lactamase_39_45,TEM-1,beta-lactamase_39,P62593,,YES,45,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-2.421,-2.421,,,,E,B,0.48,-0.3,2.256,,77.62,HHA,-2.30267,0.0495842,0.00452842,0.890469 beta-lactamase_39_I54I,beta-lactamase_39_54,TEM-1,beta-lactamase_39,P62593,,YES,54,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-2.838,-2.838,,,0.669,E,B,0.48,-0.14,1.349,,73.78,BHH,-2.337,0.0495842,0.00403589,0.929814 beta-lactamase_39_I93I,beta-lactamase_39_93,TEM-1,beta-lactamase_39,P62593,,YES,93,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.401,-1.401,,,0.128,E,B,0.48,0.44,1.757,,67.83,BHB,-1.873,0.0495842,0.00527066,0.935421 beta-lactamase_39_K109K,beta-lactamase_39_109,TEM-1,beta-lactamase_39,P62593,,YES,109,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.734,-1.734,,,0.787,G,A,2.34,2.21,7.243,,72.73,ABB,-1.63333,0.0495842,0.00462493,0.950082 beta-lactamase_39_K144K,beta-lactamase_39_144,TEM-1,beta-lactamase_39,P62593,,YES,144,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-2.388,-2.388,,,0.863,H,A,2.34,1.27,14.556,14.556,77.62,OBA,-1.904,0.0495842,0.00481141,0.920948 beta-lactamase_39_K190K,beta-lactamase_39_190,TEM-1,beta-lactamase_39,P62593,,YES,190,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.994,-1.994,,,0.371,H,A,2.34,0.16,1.513,,77.62,BBH,-1.64167,0.0495842,0.00574527,0.940217 beta-lactamase_39_K213K,beta-lactamase_39_213,TEM-1,beta-lactamase_39,P62593,,YES,213,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.81,-1.81,,,0.67,,A,2.34,0.29,2.648,,67.83,ABH,-1.57767,0.0495842,0.00610411,0.925652 beta-lactamase_39_K232K,beta-lactamase_39_232,TEM-1,beta-lactamase_39,P62593,,YES,232,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.012,-1.012,,,,E,B,2.34,-1.1,0.335,,65.03,ABP,-1.238,0.0495842,0.00313441,0.521358 beta-lactamase_39_K254K,beta-lactamase_39_254,TEM-1,beta-lactamase_39,P62593,,YES,254,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-2.126,-2.126,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.0495842,0.00369,0.924773 beta-lactamase_39_K286K,beta-lactamase_39_286,TEM-1,beta-lactamase_39,P62593,,YES,286,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.111,-1.111,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.0495842,,0.909877 beta-lactamase_39_K30K,beta-lactamase_39_30,TEM-1,beta-lactamase_39,P62593,,YES,30,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-2.307,-2.307,,,0.142,H,A,2.34,-0.65,6.717,,93.01,HBH,-2.32833,0.0495842,0.00448593,0.922085 beta-lactamase_39_K32K,beta-lactamase_39_32,TEM-1,beta-lactamase_39,P62593,,YES,32,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.984,-1.984,,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.0495842,0.00401283,0.934565 beta-lactamase_39_K53K,beta-lactamase_39_53,TEM-1,beta-lactamase_39,P62593,,YES,53,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-2.313,-2.313,,,0.589,,B,2.34,1.15,15.633,15.633,77.62,OBH,-2.1,0.0495842,0.00383383,0.93177 beta-lactamase_39_K71K,beta-lactamase_39_71,TEM-1,beta-lactamase_39,P62593,,YES,71,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-0.8,-0.8,,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.0495842,0.00103192,0.452057 beta-lactamase_39_L100L,beta-lactamase_39_100,TEM-1,beta-lactamase_39,P62593,,YES,100,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.218,-1.218,,,0.343,,B,0.55,0.13,8.311,,63.29,AHH,-1.23467,0.0495842,0.00413885,0.933847 beta-lactamase_39_L111L,beta-lactamase_39_111,TEM-1,beta-lactamase_39,P62593,,YES,111,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.76,-1.76,,,0.328,T,A,0.55,0.93,4.334,,64.34,BHP,-1.884,0.0495842,0.00480671,0.930479 beta-lactamase_39_L120L,beta-lactamase_39_120,TEM-1,beta-lactamase_39,P62593,,YES,120,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.044,-1.044,,,,H,A,0.55,-1.13,22.254,22.254,64.69,AHO,-1.13633,0.0495842,0.00143563,0.864891 beta-lactamase_39_L135L,beta-lactamase_39_135,TEM-1,beta-lactamase_39,P62593,,YES,135,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.002,-1.002,,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.0495842,0.00244423,0.853292 beta-lactamase_39_L136L,beta-lactamase_39_136,TEM-1,beta-lactamase_39,P62593,,YES,136,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.232,-1.232,,,,H,A,0.55,-0.34,0.336,,48.95,HHH,-1.088,0.0495842,0.00442304,0.826626 beta-lactamase_39_L137L,beta-lactamase_39_137,TEM-1,beta-lactamase_39,P62593,,YES,137,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.03,-1.03,,,,H,A,0.55,-0.38,0.674,,42.31,HHP,-1.58933,0.0495842,0.00278599,0.873748 beta-lactamase_39_L146L,beta-lactamase_39_146,TEM-1,beta-lactamase_39,P62593,,YES,146,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.462,-1.462,,,0.007,H,A,0.55,-0.56,1.953,,64.69,AHP,-1.656,0.0495842,0.00474542,0.922602 beta-lactamase_39_L150L,beta-lactamase_39_150,TEM-1,beta-lactamase_39,P62593,,YES,150,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.326,-1.326,,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.0495842,0.00463171,0.914653 beta-lactamase_39_L160L,beta-lactamase_39_160,TEM-1,beta-lactamase_39,P62593,,YES,160,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.977,-0.977,,,0.022,,B,0.55,-0.6,0.895,,44.41,BHA,-0.936,0.0495842,0.00193775,0.867452 beta-lactamase_39_L167L,beta-lactamase_39_167,TEM-1,beta-lactamase_39,P62593,,YES,167,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.138,-1.138,,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.0495842,0.00303566,0.868716 beta-lactamase_39_L188L,beta-lactamase_39_188,TEM-1,beta-lactamase_39,P62593,,YES,188,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.166,-1.166,,,,H,A,0.55,-0.3,2.982,,60.14,PHB,-1.47033,0.0495842,0.00295687,0.913757 beta-lactamase_39_L191L,beta-lactamase_39_191,TEM-1,beta-lactamase_39,P62593,,YES,191,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.087,-1.087,,,,H,A,0.55,0.09,1.372,,63.29,BHH,-1.445,0.0495842,0.00263549,0.877957 beta-lactamase_39_L192L,beta-lactamase_39_192,TEM-1,beta-lactamase_39,P62593,,YES,192,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.254,-1.254,,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.0495842,0.00558728,0.902515 beta-lactamase_39_L196L,beta-lactamase_39_196,TEM-1,beta-lactamase_39,P62593,,YES,196,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-2.478,-2.478,,,0.518,S,A,0.55,1.35,12.152,12.152,77.62,AHH,-1.839,0.0495842,0.00512144,0.957913 beta-lactamase_39_L197L,beta-lactamase_39_197,TEM-1,beta-lactamase_39,P62593,,YES,197,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.853,-0.853,,,0.007,S,B,0.55,0.33,1.559,,60.14,HHP,-1.833,0.0495842,0.00144602,0.841618 beta-lactamase_39_L199L,beta-lactamase_39_199,TEM-1,beta-lactamase_39,P62593,,YES,199,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-2.942,-2.942,,,0.832,H,A,0.55,0.42,15.504,15.504,77.62,PHH,-2.32933,0.0495842,0.0048649,0.942934 beta-lactamase_39_L205L,beta-lactamase_39_205,TEM-1,beta-lactamase_39,P62593,,YES,205,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.922,-0.922,,,,H,A,0.55,-0.46,0.846,,42.31,PHH,-1.57767,0.0495842,0.00255802,0.822707 beta-lactamase_39_L218L,beta-lactamase_39_218,TEM-1,beta-lactamase_39,P62593,,YES,218,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.391,-1.391,,,,I,b,0.55,-0.53,2.038,,74.48,OHH,-1.58867,0.0495842,0.00618274,0.93102 beta-lactamase_39_L219L,beta-lactamase_39_219,TEM-1,beta-lactamase_39,P62593,,YES,219,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.313,-1.313,,,,I,A,0.55,-0.51,19.842,19.842,74.48,HHB,-1.21533,0.0495842,0.00664345,0.929963 beta-lactamase_39_L223L,beta-lactamase_39_223,TEM-1,beta-lactamase_39,P62593,,YES,223,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.055,-1.055,,,0.27,,B,0.55,0.09,1.511,,74.48,HHO,-1.35033,0.0495842,0.00372793,0.910142 beta-lactamase_39_L248L,beta-lactamase_39_248,TEM-1,beta-lactamase_39,P62593,,YES,248,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.794,-1.794,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.0495842,0.00428493,0.886269 beta-lactamase_39_L284L,beta-lactamase_39_284,TEM-1,beta-lactamase_39,P62593,,YES,284,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.981,-1.981,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.0495842,0.0686156,0.940748 beta-lactamase_39_L28L,beta-lactamase_39_28,TEM-1,beta-lactamase_39,P62593,,YES,28,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.579,-1.579,,,0.277,H,A,0.55,-0.16,3.262,,93.01,PHH,-2.11333,0.0495842,0.00359321,0.932458 beta-lactamase_39_L38L,beta-lactamase_39_38,TEM-1,beta-lactamase_39,P62593,,YES,38,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.343,-1.343,,,0.088,H,A,0.55,0.2,17.089,17.089,64.34,PHO,-1.78033,0.0495842,0.00373244,0.930963 beta-lactamase_39_L47L,beta-lactamase_39_47,TEM-1,beta-lactamase_39,P62593,,YES,47,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.876,-1.876,,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.0495842,0.00439844,0.876005 beta-lactamase_39_L49L,beta-lactamase_39_49,TEM-1,beta-lactamase_39,P62593,,YES,49,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.897,-1.897,,,0.131,T,A,0.55,0.04,13.838,13.838,64.69,AHP,-1.99233,0.0495842,0.00401477,0.935136 beta-lactamase_39_L55L,beta-lactamase_39_55,TEM-1,beta-lactamase_39,P62593,,YES,55,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.86,-1.86,,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.0495842,0.00403741,0.938786 beta-lactamase_39_L73L,beta-lactamase_39_73,TEM-1,beta-lactamase_39,P62593,,YES,73,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.507,-1.507,,,,H,A,0.55,-0.64,2.09,,67.83,HHH,-1.487,0.0495842,0.00488983,0.945297 beta-lactamase_39_L74L,beta-lactamase_39_74,TEM-1,beta-lactamase_39,P62593,,YES,74,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.296,-1.296,,,,H,A,0.55,-0.91,1.581,,50,HHO,-1.34933,0.0495842,0.00493255,0.906649 beta-lactamase_39_L79L,beta-lactamase_39_79,TEM-1,beta-lactamase_39,P62593,,YES,79,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.842,-0.842,,,0.007,H,A,0.55,-0.16,0.823,,50.35,HHP,-1.44333,0.0495842,0.000947397,0.831434 beta-lactamase_39_L89L,beta-lactamase_39_89,TEM-1,beta-lactamase_39,P62593,,YES,89,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.096,-1.096,,,0.168,T,A,0.55,0.63,3.233,,64.34,PHO,-1.75767,0.0495842,0.00207068,0.902467 beta-lactamase_39_M115M,beta-lactamase_39_115,TEM-1,beta-lactamase_39,P62593,,YES,115,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.389,-1.389,,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.0495842,0.0034337,0.854955 beta-lactamase_39_M127M,beta-lactamase_39_127,TEM-1,beta-lactamase_39,P62593,,YES,127,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-2.251,-2.251,,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.0495842,0.00437927,1.15779 beta-lactamase_39_M153M,beta-lactamase_39_153,TEM-1,beta-lactamase_39,P62593,,YES,153,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-3.193,-3.193,,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.0495842,0.00509109,0.967116 beta-lactamase_39_M180M,beta-lactamase_39_180,TEM-1,beta-lactamase_39,P62593,,YES,180,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-2.795,-2.795,,,0.242,,B,0.55,-0.94,3.579,,77.62,PHO,-1.56433,0.0495842,0.00552048,0.942662 beta-lactamase_39_M184M,beta-lactamase_39_184,TEM-1,beta-lactamase_39,P62593,,YES,184,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.593,-1.593,,,,H,A,0.55,-0.87,2.893,,62.94,HHH,-1.41,0.0495842,0.00356019,0.911272 beta-lactamase_39_M209M,beta-lactamase_39_209,TEM-1,beta-lactamase_39,P62593,,YES,209,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.442,-1.442,,,,H,A,0.55,-0.97,1.167,,64.69,HHA,-1.52633,0.0495842,0.00625021,0.860839 beta-lactamase_39_M270M,beta-lactamase_39_270,TEM-1,beta-lactamase_39,P62593,,YES,270,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.723,-1.723,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.0495842,0.00767762,1.0884 beta-lactamase_39_M66M,beta-lactamase_39_66,TEM-1,beta-lactamase_39,P62593,,YES,66,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.362,-1.362,,,0.013,,A,0.55,-0.7,1.319,,73.08,OHH,-1.49567,0.0495842,0.00412876,0.887158 beta-lactamase_39_M67M,beta-lactamase_39_67,TEM-1,beta-lactamase_39,P62593,,YES,67,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-2.231,-2.231,,,0.006,G,P,0.55,-0.81,1.463,,65.03,HHP,-1.502,0.0495842,0.00409753,0.887736 beta-lactamase_39_N130N,beta-lactamase_39_130,TEM-1,beta-lactamase_39,P62593,,YES,130,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-0.798,-0.798,,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.0495842,0.000683376,0.853979 beta-lactamase_39_N134N,beta-lactamase_39_134,TEM-1,beta-lactamase_39,P62593,,YES,134,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-0.879,-0.879,,,0.138,H,A,0.61,-0.6,1.441,,53.15,HPH,-1.02233,0.0495842,0.000644786,0.879989 beta-lactamase_39_N152N,beta-lactamase_39_152,TEM-1,beta-lactamase_39,P62593,,YES,152,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-2.757,-2.757,,,0.863,H,A,0.61,0.92,4.038,,77.62,BPH,-2.97,0.0495842,0.00471429,0.925881 beta-lactamase_39_N168N,beta-lactamase_39_168,TEM-1,beta-lactamase_39,P62593,,YES,168,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-1.029,-1.029,,,0.113,G,A,0.61,-0.4,0.822,,44.41,HPA,-1.13233,0.0495842,0.00288667,0.88007 beta-lactamase_39_N173N,beta-lactamase_39_173,TEM-1,beta-lactamase_39,P62593,,YES,173,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-2.663,-2.663,,,1.044,T,l,0.61,1.25,1.426,,77.62,OPA,-1.46633,0.0495842,0.0033769,0.919728 beta-lactamase_39_N274N,beta-lactamase_39_274,TEM-1,beta-lactamase_39,P62593,,YES,274,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-2.082,-2.082,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.0495842,0.0110418,0.930811 beta-lactamase_39_N50N,beta-lactamase_39_50,TEM-1,beta-lactamase_39,P62593,,YES,50,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-2.979,-2.979,,,0.912,T,A,0.61,1.24,10.736,,77.62,HPP,-2.134,0.0495842,0.0047211,0.919199 beta-lactamase_39_N98N,beta-lactamase_39_98,TEM-1,beta-lactamase_39,P62593,,YES,98,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-2.973,-2.973,,,0.963,G,A,0.61,1.35,14.853,14.853,77.62,PPA,-2.07867,0.0495842,0.00505389,0.938172 beta-lactamase_39_P105P,beta-lactamase_39_105,TEM-1,beta-lactamase_39,P62593,,YES,105,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.813,-0.813,,,0.226,T,A,0.52,0.8,1.222,,63.29,POH,-1.01533,0.0495842,0.0011981,0.699615 beta-lactamase_39_P143P,beta-lactamase_39_143,TEM-1,beta-lactamase_39,P62593,,YES,143,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.967,-0.967,,,0.075,H,A,0.52,-0.37,0.976,,66.78,OOB,-1.354,0.0495842,0.00114551,0.729886 beta-lactamase_39_P165P,beta-lactamase_39_165,TEM-1,beta-lactamase_39,P62593,,YES,165,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.373,-1.373,,,0.203,T,A,0.52,-0.31,3.907,,73.78,AOA,-1.359,0.0495842,0.00549538,0.795419 beta-lactamase_39_P172P,beta-lactamase_39_172,TEM-1,beta-lactamase_39,P62593,,YES,172,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.998,-0.998,,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.0495842,0.00312594,0.818498 beta-lactamase_39_P181P,beta-lactamase_39_181,TEM-1,beta-lactamase_39,P62593,,YES,181,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.813,-0.813,,,,H,A,0.52,-1.14,1.946,,61.54,HOH,-1.795,0.0495842,0.000703122,0.632067 beta-lactamase_39_P217P,beta-lactamase_39_217,TEM-1,beta-lactamase_39,P62593,,YES,217,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-2.062,-2.062,,,0.496,I,A,0.52,-0.33,21.172,21.172,74.48,OOH,-1.64333,0.0495842,0.00463211,0.894692 beta-lactamase_39_P224P,beta-lactamase_39_224,TEM-1,beta-lactamase_39,P62593,,YES,224,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.893,-0.893,,,0.383,,B,0.52,-0.3,3.169,,74.48,HOH,-1.26433,0.0495842,0.00189564,0.760046 beta-lactamase_39_P250P,beta-lactamase_39_250,TEM-1,beta-lactamase_39,P62593,,YES,250,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-2.335,-2.335,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.0495842,0.00550899,0.903904 beta-lactamase_39_P255P,beta-lactamase_39_255,TEM-1,beta-lactamase_39,P62593,,YES,255,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-2.266,-2.266,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.0495842,0.00499612,0.748945 beta-lactamase_39_P25P,beta-lactamase_39_25,TEM-1,beta-lactamase_39,P62593,,YES,25,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.526,-1.526,,,0.624,H,A,0.52,0.14,1.157,,73.08,BOA,-2.15367,0.0495842,0.00347571,0.897508 beta-lactamase_39_P60P,beta-lactamase_39_60,TEM-1,beta-lactamase_39,P62593,,YES,60,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-2.469,-2.469,,,0.256,T,A,0.52,-0.56,21.37,21.37,77.62,BOA,-1.97633,0.0495842,0.00521318,0.869788 beta-lactamase_39_P65P,beta-lactamase_39_65,TEM-1,beta-lactamase_39,P62593,,YES,65,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.894,-0.894,,,0.098,E,B,0.52,-0.62,0.623,,40.56,HOH,-1.03233,0.0495842,0.00152776,0.657347 beta-lactamase_39_Q203Q,beta-lactamase_39_203,TEM-1,beta-lactamase_39,P62593,,YES,203,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.168,-2.168,,,0.47,H,A,0.64,-0.38,1.453,,65.38,BPP,-1.614,0.0495842,0.00631514,0.928735 beta-lactamase_39_Q204Q,beta-lactamase_39_204,TEM-1,beta-lactamase_39,P62593,,YES,204,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-1.382,-1.382,,,0.204,H,A,0.64,0.09,0.489,,66.08,PPH,-1.49067,0.0495842,0.00364106,0.936366 beta-lactamase_39_Q267Q,beta-lactamase_39_267,TEM-1,beta-lactamase_39,P62593,,YES,267,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.308,-2.308,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.0495842,0.0102128,0.949533 beta-lactamase_39_Q276Q,beta-lactamase_39_276,TEM-1,beta-lactamase_39,P62593,,YES,276,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-1.144,-1.144,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.0495842,0.0191712,0.925493 beta-lactamase_39_Q37Q,beta-lactamase_39_37,TEM-1,beta-lactamase_39,P62593,,YES,37,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.134,-2.134,,,0.613,H,A,0.64,1.98,22.282,22.282,73.08,APH,-2.06967,0.0495842,0.00425833,0.930435 beta-lactamase_39_Q86Q,beta-lactamase_39_86,TEM-1,beta-lactamase_39,P62593,,YES,86,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.4,-2.4,,,0.696,S,A,0.64,2.38,27.704,27.704,77.62,OPA,-1.61067,0.0495842,0.00450027,0.93652 beta-lactamase_39_Q88Q,beta-lactamase_39_88,TEM-1,beta-lactamase_39,P62593,,YES,88,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.086,-2.086,,,0.807,,B,0.64,2.03,11.108,11.108,77.62,APH,-1.53433,0.0495842,0.00504167,0.940185 beta-lactamase_39_Q97Q,beta-lactamase_39_97,TEM-1,beta-lactamase_39,P62593,,YES,97,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.072,-2.072,,,0.823,G,A,0.64,2.42,4.457,,77.62,PPP,-2.43833,0.0495842,0.0045116,0.922578 beta-lactamase_39_R118R,beta-lactamase_39_118,TEM-1,beta-lactamase_39,P62593,,YES,118,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.413,-2.413,,,0.457,H,A,1.2,1.39,3.961,,77.62,HBA,-1.785,0.0495842,0.00538794,0.958198 beta-lactamase_39_R159R,beta-lactamase_39_159,TEM-1,beta-lactamase_39,P62593,,YES,159,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-0.94,-0.94,,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.0495842,0.00108472,0.880218 beta-lactamase_39_R162R,beta-lactamase_39_162,TEM-1,beta-lactamase_39,P62593,,YES,162,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.016,-1.016,,,0.124,S,B,1.2,-0.37,31.656,31.656,64.69,ABH,-1.25,0.0495842,0.000561334,0.84822 beta-lactamase_39_R176R,beta-lactamase_39_176,TEM-1,beta-lactamase_39,P62593,,YES,176,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-0.863,-0.863,,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.0495842,0.00105554,0.91554 beta-lactamase_39_R189R,beta-lactamase_39_189,TEM-1,beta-lactamase_39,P62593,,YES,189,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.844,-1.844,,,0.278,H,A,1.2,1.01,12.11,12.11,72.73,HBB,-1.668,0.0495842,0.0050699,0.952152 beta-lactamase_39_R202R,beta-lactamase_39_202,TEM-1,beta-lactamase_39,P62593,,YES,202,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.292,-1.292,,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.0495842,0.00321899,0.934295 beta-lactamase_39_R220R,beta-lactamase_39_220,TEM-1,beta-lactamase_39,P62593,,YES,220,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-0.942,-0.942,,,0.295,I,A,1.2,-0.76,1.596,,74.48,HBP,-1.33633,0.0495842,0.00232421,0.903989 beta-lactamase_39_R239R,beta-lactamase_39_239,TEM-1,beta-lactamase_39,P62593,,YES,239,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-0.819,-0.819,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.0495842,0.00213852,0.878382 beta-lactamase_39_R242R,beta-lactamase_39_242,TEM-1,beta-lactamase_39,P62593,,YES,242,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.319,-1.319,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.0495842,0.00452879,0.803548 beta-lactamase_39_R257R,beta-lactamase_39_257,TEM-1,beta-lactamase_39,P62593,,YES,257,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.533,-1.533,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.0495842,0.00756629,0.780825 beta-lactamase_39_R273R,beta-lactamase_39_273,TEM-1,beta-lactamase_39,P62593,,YES,273,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.314,-2.314,,,0.564,H,A,1.2,1.57,2.163,,73.78,ABP,-1.841,0.0495842,0.0077952,0.944317 beta-lactamase_39_R275R,beta-lactamase_39_275,TEM-1,beta-lactamase_39,P62593,,YES,275,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.397,-1.397,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.0495842,0.0141984,0.841738 beta-lactamase_39_R41R,beta-lactamase_39_41,TEM-1,beta-lactamase_39,P62593,,YES,41,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-0.942,-0.942,,,0.321,E,B,1.2,-0.07,0.327,,65.03,HBH,-1.30267,0.0495842,0.00123327,0.902594 beta-lactamase_39_R59R,beta-lactamase_39_59,TEM-1,beta-lactamase_39,P62593,,YES,59,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.345,-1.345,,,0.329,S,L,1.2,-0.09,1.806,,73.08,HBO,-2.24267,0.0495842,0.00318082,0.903153 beta-lactamase_39_R63R,beta-lactamase_39_63,TEM-1,beta-lactamase_39,P62593,,YES,63,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-0.943,-0.943,,,0.218,,B,1.2,-0.31,0.326,,44.06,ABH,-0.992333,0.0495842,0.00126938,0.90033 beta-lactamase_39_R81R,beta-lactamase_39_81,TEM-1,beta-lactamase_39,P62593,,YES,81,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.466,-1.466,,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.0495842,0.00499763,0.910371 beta-lactamase_39_R91R,beta-lactamase_39_91,TEM-1,beta-lactamase_39,P62593,,YES,91,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.392,-1.392,,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.0495842,0.00380226,0.92198 beta-lactamase_39_R92R,beta-lactamase_39_92,TEM-1,beta-lactamase_39,P62593,,YES,92,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.718,-1.718,,,0.479,E,B,1.2,1.36,0.389,,65.38,BBH,-1.50367,0.0495842,0.00429626,0.960264 beta-lactamase_39_S104S,beta-lactamase_39_104,TEM-1,beta-lactamase_39,P62593,,YES,104,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.015,-1.015,,,0.04,,b,0.27,0.57,4.02,,63.29,HPO,-1.05267,0.0495842,0.00218083,0.909184 beta-lactamase_39_S122S,beta-lactamase_39_122,TEM-1,beta-lactamase_39,P62593,,YES,122,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.406,-2.406,,,0.352,H,A,0.27,-0.54,2.004,,77.62,OPH,-1.39767,0.0495842,0.00497825,0.972744 beta-lactamase_39_S128S,beta-lactamase_39_128,TEM-1,beta-lactamase_39,P62593,,YES,128,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-0.84,-0.84,,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.0495842,0.00071483,0.501489 beta-lactamase_39_S201S,beta-lactamase_39_201,TEM-1,beta-lactamase_39,P62593,,YES,201,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.183,-1.183,,,0.064,H,A,0.27,-0.07,3.54,,64.69,HPB,-1.451,0.0495842,0.00198815,0.920216 beta-lactamase_39_S221S,beta-lactamase_39_221,TEM-1,beta-lactamase_39,P62593,,YES,221,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.754,-1.754,,,0.624,H,A,0.27,-0.2,2.69,,74.48,BPH,-1.59967,0.0495842,0.0046094,0.933453 beta-lactamase_39_S233S,beta-lactamase_39_233,TEM-1,beta-lactamase_39,P62593,,YES,233,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.886,-1.886,,,0.016,E,B,0.27,-1.01,5.361,,77.62,BPO,-1.17267,0.0495842,0.00311415,0.876639 beta-lactamase_39_S241S,beta-lactamase_39_241,TEM-1,beta-lactamase_39,P62593,,YES,241,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.433,-1.433,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.0495842,0.00452736,0.902754 beta-lactamase_39_S256S,beta-lactamase_39_256,TEM-1,beta-lactamase_39,P62593,,YES,256,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.621,-1.621,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.0495842,0.00710634,0.890986 beta-lactamase_39_S266S,beta-lactamase_39_266,TEM-1,beta-lactamase_39,P62593,,YES,266,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.369,-1.369,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.0495842,0.0140785,0.940212 beta-lactamase_39_S283S,beta-lactamase_39_283,TEM-1,beta-lactamase_39,P62593,,YES,283,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.638,-1.638,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.0495842,0.0429138,0.932188 beta-lactamase_39_S51S,beta-lactamase_39_51,TEM-1,beta-lactamase_39,P62593,,YES,51,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.526,-1.526,,,0.496,T,A,0.27,0.26,2.964,,72.73,PPO,-1.88467,0.0495842,0.00504821,0.942538 beta-lactamase_39_S57S,beta-lactamase_39_57,TEM-1,beta-lactamase_39,P62593,,YES,57,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.918,-1.918,,,0.352,E,B,0.27,-0.18,2.3,,72.73,APH,-2.29167,0.0495842,0.00492804,0.922619 beta-lactamase_39_S68S,beta-lactamase_39_68,TEM-1,beta-lactamase_39,P62593,,YES,68,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-0.913,-0.913,,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.0495842,0.000800065,0.355932 beta-lactamase_39_S80S,beta-lactamase_39_80,TEM-1,beta-lactamase_39,P62593,,YES,80,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.029,-2.029,,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.0495842,0.00565569,0.936349 beta-lactamase_39_S96S,beta-lactamase_39_96,TEM-1,beta-lactamase_39,P62593,,YES,96,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.27,-2.27,,,0.368,,b,0.27,0.39,2.516,,73.78,HPP,-2.019,0.0495842,0.00551835,0.952929 beta-lactamase_39_T107T,beta-lactamase_39_107,TEM-1,beta-lactamase_39,P62593,,YES,107,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.117,-1.117,,,,G,A,0.22,-0.06,2.686,,67.83,HPA,-1.265,0.0495842,0.00239347,0.90349 beta-lactamase_39_T112T,beta-lactamase_39_112,TEM-1,beta-lactamase_39,P62593,,YES,112,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.186,-2.186,,,0.921,T,A,0.22,1.06,2.87,,73.78,HPA,-1.925,0.0495842,0.00531334,0.948136 beta-lactamase_39_T116T,beta-lactamase_39_116,TEM-1,beta-lactamase_39,P62593,,YES,116,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.28,-1.28,,,0.115,E,B,0.22,-0.12,1.133,,67.48,HPH,-1.39967,0.0495842,0.00336175,0.896938 beta-lactamase_39_T126T,beta-lactamase_39_126,TEM-1,beta-lactamase_39,P62593,,YES,126,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.122,-1.122,,,0.05,H,A,0.22,-0.05,0.586,,44.41,HPH,-1.60467,0.0495842,0.00244552,0.878358 beta-lactamase_39_T131T,beta-lactamase_39_131,TEM-1,beta-lactamase_39,P62593,,YES,131,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.328,-1.328,,,,H,A,0.22,-0.69,3.306,,67.48,PPH,-1.00867,0.0495842,0.00345886,0.930074 beta-lactamase_39_T138T,beta-lactamase_39_138,TEM-1,beta-lactamase_39,P62593,,YES,138,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.506,-2.506,,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.0495842,0.00487868,0.938587 beta-lactamase_39_T139T,beta-lactamase_39_139,TEM-1,beta-lactamase_39,P62593,,YES,139,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.901,-1.901,,,0.216,H,A,0.22,0.39,0.421,,77.62,PPH,-2.04667,0.0495842,0.00441837,0.901033 beta-lactamase_39_T147T,beta-lactamase_39_147,TEM-1,beta-lactamase_39,P62593,,YES,147,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.149,-1.149,,,0.281,H,A,0.22,-0.68,13.843,13.843,64.34,HPH,-1.456,0.0495842,0.00226017,0.926494 beta-lactamase_39_T158T,beta-lactamase_39_158,TEM-1,beta-lactamase_39,P62593,,YES,158,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.116,-1.116,,,0.036,,B,0.22,-0.85,2.755,,69.58,HPB,-1.269,0.0495842,0.00341825,0.882989 beta-lactamase_39_T178T,beta-lactamase_39_178,TEM-1,beta-lactamase_39,P62593,,YES,178,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-0.791,-0.791,,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.0495842,0.000684366,0.866313 beta-lactamase_39_T179T,beta-lactamase_39_179,TEM-1,beta-lactamase_39,P62593,,YES,179,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.085,-1.085,,,,E,B,0.22,-1.38,3.772,,73.08,PPH,-1.557,0.0495842,0.00226045,0.827336 beta-lactamase_39_T186T,beta-lactamase_39_186,TEM-1,beta-lactamase_39,P62593,,YES,186,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.522,-2.522,,,0.396,H,A,0.22,-0.28,0.515,,77.62,HPP,-1.77633,0.0495842,0.00485034,0.943773 beta-lactamase_39_T187T,beta-lactamase_39_187,TEM-1,beta-lactamase_39,P62593,,YES,187,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.401,-1.401,,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.0495842,0.00491782,0.900937 beta-lactamase_39_T193T,beta-lactamase_39_193,TEM-1,beta-lactamase_39,P62593,,YES,193,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.914,-1.914,,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.0495842,0.00482669,0.939157 beta-lactamase_39_T198T,beta-lactamase_39_198,TEM-1,beta-lactamase_39,P62593,,YES,198,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.168,-2.168,,,0.489,,B,0.22,-0.13,3.614,,73.78,HPH,-1.98767,0.0495842,0.004311,0.93539 beta-lactamase_39_T263T,beta-lactamase_39_263,TEM-1,beta-lactamase_39,P62593,,YES,263,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.031,-2.031,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.0495842,0.0110582,0.94556 beta-lactamase_39_T264T,beta-lactamase_39_264,TEM-1,beta-lactamase_39,P62593,,YES,264,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.985,-1.985,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.0495842,0.0119399,0.9276 beta-lactamase_39_T269T,beta-lactamase_39_269,TEM-1,beta-lactamase_39,P62593,,YES,269,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.156,-2.156,,,0.646,H,A,0.53,0.4,3.889,,77.62,HPH,-1.96733,0.0495842,0.00950944,0.955525 beta-lactamase_39_T27T,beta-lactamase_39_27,TEM-1,beta-lactamase_39,P62593,,YES,27,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.905,-1.905,,,0.007,H,A,0.22,-0.37,0.745,,93.01,APH,-1.97933,0.0495842,0.00306559,0.875943 beta-lactamase_39_T69T,beta-lactamase_39_69,TEM-1,beta-lactamase_39,P62593,,YES,69,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-0.973,-0.973,,,,G,A,0.22,-1.24,4.194,,93.01,PPH,-1.01833,0.0495842,0.00127498,0.843892 beta-lactamase_39_V101V,beta-lactamase_39_101,TEM-1,beta-lactamase_39,P62593,,YES,101,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.295,-1.295,,,0.342,,B,0.44,0,2.96,,73.08,HHA,-1.54367,0.0495842,0.00374492,0.923635 beta-lactamase_39_V106V,beta-lactamase_39_106,TEM-1,beta-lactamase_39,P62593,,YES,106,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.218,-1.218,,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.0495842,0.00304168,0.952403 beta-lactamase_39_V117V,beta-lactamase_39_117,TEM-1,beta-lactamase_39,P62593,,YES,117,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.53,-1.53,,,,H,A,0.44,-0.34,1.182,,65.03,PHB,-1.741,0.0495842,0.00467906,0.833375 beta-lactamase_39_V157V,beta-lactamase_39_157,TEM-1,beta-lactamase_39,P62593,,YES,157,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.751,-1.751,,,0.308,S,a,0.44,-0.75,10.364,10.364,69.58,BHP,-2.00767,0.0495842,0.00506849,0.941226 beta-lactamase_39_V214V,beta-lactamase_39_214,TEM-1,beta-lactamase_39,P62593,,YES,214,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.299,-1.299,,,0.375,S,A,0.44,-0.44,18.838,18.838,74.48,BHH,-1.53733,0.0495842,0.00628442,0.95388 beta-lactamase_39_V259V,beta-lactamase_39_259,TEM-1,beta-lactamase_39,P62593,,YES,259,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.522,-1.522,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.0495842,0.0070773,0.915286 beta-lactamase_39_V260V,beta-lactamase_39_260,TEM-1,beta-lactamase_39,P62593,,YES,260,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.101,-1.101,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.0495842,0.00471757,0.870649 beta-lactamase_39_V29V,beta-lactamase_39_29,TEM-1,beta-lactamase_39,P62593,,YES,29,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-2.856,-2.856,,,0.733,H,A,0.44,-0.78,1.287,,93.01,HHB,-2.24733,0.0495842,0.00318969,0.940572 beta-lactamase_39_V31V,beta-lactamase_39_31,TEM-1,beta-lactamase_39,P62593,,YES,31,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.822,-1.822,,,,H,A,0.44,-0.46,2.885,,73.78,BHB,-2.03767,0.0495842,0.00478065,0.895013 beta-lactamase_39_V42V,beta-lactamase_39_42,TEM-1,beta-lactamase_39,P62593,,YES,42,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.564,-1.564,,,0.017,E,B,0.44,-0.51,1.86,,63.99,BHO,-1.042,0.0495842,0.00404515,0.870899 beta-lactamase_39_V72V,beta-lactamase_39_72,TEM-1,beta-lactamase_39,P62593,,YES,72,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.658,-1.658,,,,H,A,0.44,-1.03,1.92,,65.73,BHH,-1.32167,0.0495842,0.00501194,0.905821 beta-lactamase_39_V78V,beta-lactamase_39_78,TEM-1,beta-lactamase_39,P62593,,YES,78,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.459,-1.459,,,,H,A,0.44,-0.47,1.132,,63.64,HHH,-1.17833,0.0495842,0.00492501,0.918086 beta-lactamase_39_V82V,beta-lactamase_39_82,TEM-1,beta-lactamase_39,P62593,,YES,82,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.325,-1.325,,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.0495842,0.00397046,0.926212 beta-lactamase_39_W163W,beta-lactamase_39_163,TEM-1,beta-lactamase_39,P62593,,YES,163,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-1.843,-1.843,,,0.467,,B,0.47,-0.5,15.095,15.095,63.99,BHA,-1.269,0.0495842,0.00418955,0.924464 beta-lactamase_39_W208W,beta-lactamase_39_208,TEM-1,beta-lactamase_39,P62593,,YES,208,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-0.818,-0.818,,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.0495842,0.00126609,0.866393 beta-lactamase_39_W227W,beta-lactamase_39_227,TEM-1,beta-lactamase_39,P62593,,YES,227,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-0.982,-0.982,,,0.272,,B,0.47,-0.29,1.37,,74.48,OHH,-1.595,0.0495842,0.00226019,0.780785 beta-lactamase_39_W288W,beta-lactamase_39_288,TEM-1,beta-lactamase_39,P62593,,YES,288,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,,,,,,,,,,,,,BHO,,0.0495842,,0.850625 beta-lactamase_39_Y103Y,beta-lactamase_39_103,TEM-1,beta-lactamase_39,P62593,,YES,103,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-1.33,-1.33,,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.0495842,0.00443048,0.919661 beta-lactamase_39_Y262Y,beta-lactamase_39_262,TEM-1,beta-lactamase_39,P62593,,YES,262,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-1.332,-1.332,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.0495842,0.00853516,0.840198 beta-lactamase_39_Y44Y,beta-lactamase_39_44,TEM-1,beta-lactamase_39,P62593,,YES,44,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-2.547,-2.547,,,,E,B,0.21,-0.45,2.683,,73.78,OHH,-1.86267,0.0495842,0.00426364,0.83463 beta-lactamase_39_Y95Y,beta-lactamase_39_95,TEM-1,beta-lactamase_39,P62593,,YES,95,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-1.715,-1.715,,,0.122,,b,0.21,-0.37,2.341,,77.62,BHP,-2.16167,0.0495842,0.00479449,0.862754 beta-lactamase_625_A123A,beta-lactamase_625_123,TEM-1,beta-lactamase_625,P62593,,YES,123,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.834,-0.834,,,0.039,H,A,0.46,-0.72,0.895,,41.26,PHH,-1.47367,0.213352,0.0010157,0.709055 beta-lactamase_625_A124A,beta-lactamase_625_124,TEM-1,beta-lactamase_625,P62593,,YES,124,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.181,-1.181,,,,H,A,0.46,-0.9,2.027,,64.34,HHH,-1.152,0.213352,0.00481399,0.815853 beta-lactamase_625_A132A,beta-lactamase_625_132,TEM-1,beta-lactamase_625,P62593,,YES,132,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-0.9,-0.9,,,,H,A,0.46,-0.93,0.316,,64.69,PHH,-1.138,0.213352,0.000962524,0.568756 beta-lactamase_625_A133A,beta-lactamase_625_133,TEM-1,beta-lactamase_625,P62593,,YES,133,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.186,-1.186,,,,H,A,0.46,-0.86,0.373,,67.83,HHP,-0.988333,0.213352,0.00468022,0.791346 beta-lactamase_625_A148A,beta-lactamase_625_148,TEM-1,beta-lactamase_625,P62593,,YES,148,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.757,-1.757,,,0.379,H,A,0.46,-0.55,1.359,,72.73,PHH,-1.40167,0.213352,0.00547053,0.903081 beta-lactamase_625_A170A,beta-lactamase_625_170,TEM-1,beta-lactamase_625,P62593,,YES,170,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.237,-1.237,,,0.126,,L,0.46,-0.35,3.626,,64.69,AHH,-1.63267,0.213352,0.00431903,0.80029 beta-lactamase_625_A182A,beta-lactamase_625_182,TEM-1,beta-lactamase_625,P62593,,YES,182,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.777,-1.777,,,0.136,H,A,0.46,-0.66,16.784,16.784,93.01,OHH,-1.27367,0.213352,0.00559099,0.885774 beta-lactamase_625_A183A,beta-lactamase_625_183,TEM-1,beta-lactamase_625,P62593,,YES,183,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.231,-1.231,,,0.155,H,A,0.46,-0.91,23.859,23.859,77.62,HHH,-1.53367,0.213352,0.00296631,0.809982 beta-lactamase_625_A185A,beta-lactamase_625_185,TEM-1,beta-lactamase_625,P62593,,YES,185,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.406,-1.406,,,,H,A,0.46,-1.02,0.365,,65.03,HHP,-1.84033,0.213352,0.00467449,0.765009 beta-lactamase_625_A200A,beta-lactamase_625_200,TEM-1,beta-lactamase_625,P62593,,YES,200,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.878,-1.878,,,0.757,H,A,0.46,-0.19,12.672,12.672,77.62,HHP,-2.001,0.213352,0.0060056,0.903699 beta-lactamase_625_A211A,beta-lactamase_625_211,TEM-1,beta-lactamase_625,P62593,,YES,211,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.896,-1.896,,,0.369,T,A,0.46,-0.69,2.061,,77.62,AHA,-1.94633,0.213352,0.00648183,0.912183 beta-lactamase_625_A215A,beta-lactamase_625_215,TEM-1,beta-lactamase_625,P62593,,YES,215,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.503,-1.503,,,,,a,0.46,-0.93,3.583,,74.48,HHO,-1.42633,0.213352,0.00544007,0.70309 beta-lactamase_625_A222A,beta-lactamase_625_222,TEM-1,beta-lactamase_625,P62593,,YES,222,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.103,-2.103,,,0.233,H,A,0.46,-0.25,1.448,,77.62,PHH,-1.63733,0.213352,0.00466094,0.86262 beta-lactamase_625_A225A,beta-lactamase_625_225,TEM-1,beta-lactamase_625,P62593,,YES,225,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.845,-1.845,,,1,T,B,0.46,-0.38,9.874,9.874,74.48,OHO,-1.39967,0.213352,0.00465057,0.904074 beta-lactamase_625_A230A,beta-lactamase_625_230,TEM-1,beta-lactamase_625,P62593,,YES,230,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.154,-1.154,,,0.01,E,B,0.46,-1.17,0.777,,50,HHA,-1.079,0.213352,0.00516841,0.719005 beta-lactamase_625_A235A,beta-lactamase_625_235,TEM-1,beta-lactamase_625,P62593,,YES,235,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.266,-1.266,,,0.32,E,B,0.46,-0.86,0.281,,50,OHO,-0.89,0.213352,0.00493474,0.645079 beta-lactamase_625_A246A,beta-lactamase_625_246,TEM-1,beta-lactamase_625,P62593,,YES,246,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.121,-2.121,,,0.01,E,B,0.46,-1.01,1.201,,73.78,HHH,-1.55633,0.213352,0.00569458,0.682558 beta-lactamase_625_A247A,beta-lactamase_625_247,TEM-1,beta-lactamase_625,P62593,,YES,247,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.48,-1.48,,,0.007,E,B,0.55,-0.72,,,63.99,HHH,-1.79833,0.213352,0.00611275,0.781796 beta-lactamase_625_A268A,beta-lactamase_625_268,TEM-1,beta-lactamase_625,P62593,,YES,268,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.023,-2.023,,,0.471,H,A,0.55,0.3,,,65.73,PHP,-2.16233,0.213352,0.0102525,0.845728 beta-lactamase_625_A278A,beta-lactamase_625_278,TEM-1,beta-lactamase_625,P62593,,YES,278,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.348,-1.348,,,0.015,H,A,0.48,-0.85,,,63.29,HHA,-1.41833,0.213352,0.0310297,0.802759 beta-lactamase_625_A282A,beta-lactamase_625_282,TEM-1,beta-lactamase_625,P62593,,YES,282,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.586,-1.586,,,0.007,H,A,0.55,0.34,,,63.99,OHP,-1.82367,0.213352,0.0449821,0.806184 beta-lactamase_625_A34A,beta-lactamase_625_34,TEM-1,beta-lactamase_625,P62593,,YES,34,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-2.059,-2.059,,,,H,A,0.46,-0.54,3.614,,73.78,AHA,-1.74967,0.213352,0.00407913,0.822368 beta-lactamase_625_A40A,beta-lactamase_625_40,TEM-1,beta-lactamase_625,P62593,,YES,40,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.402,-1.402,,,0.155,S,B,0.46,0.21,1.357,,73.78,OHB,-1.40267,0.213352,0.00490026,0.721506 beta-lactamase_625_A77A,beta-lactamase_625_77,TEM-1,beta-lactamase_625,P62593,,YES,77,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.234,-1.234,,,0.039,H,A,0.46,-0.56,1.708,,64.34,OHH,-1.294,0.213352,0.00282362,0.858916 beta-lactamase_625_A84A,beta-lactamase_625_84,TEM-1,beta-lactamase_625,P62593,,YES,84,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.651,-1.651,,,0.65,T,A,0.46,0.96,1.863,,68.18,AHO,-1.24267,0.213352,0.00503822,0.892131 beta-lactamase_625_C121C,beta-lactamase_625_121,TEM-1,beta-lactamase_625,P62593,,YES,121,C,C,CC,Special,Special,5.07,5.07,0,0,121,121,0,108.5,108.5,0,-0.953,-0.953,,,,H,A,0.46,-0.81,1.143,,63.29,HOP,-1.46767,0.213352,0.000744322,0.637059 beta-lactamase_625_C75C,beta-lactamase_625_75,TEM-1,beta-lactamase_625,P62593,,YES,75,C,C,CC,Special,Special,5.07,5.07,0,0,121,121,0,108.5,108.5,0,-1.245,-1.245,,,,H,A,0.46,-0.87,2.141,,50,HOO,-1.24333,0.213352,0.0034616,0.857237 beta-lactamase_625_D113D,beta-lactamase_625_113,TEM-1,beta-lactamase_625,P62593,,YES,113,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.829,-1.829,,,0.665,T,A,0.75,0.91,13.179,13.179,73.08,PAO,-1.703,0.213352,0.00474112,0.888603 beta-lactamase_625_D129D,beta-lactamase_625_129,TEM-1,beta-lactamase_625,P62593,,YES,129,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.816,-0.816,,,,,B,0.75,-0.69,0.171,,34.97,PAP,-0.818,0.213352,0.00109178,0.444956 beta-lactamase_625_D155D,beta-lactamase_625_155,TEM-1,beta-lactamase_625,P62593,,YES,155,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.889,-0.889,,,0.049,,B,0.75,-0.9,4.922,,64.69,OAB,-1.62267,0.213352,0.00135315,0.536332 beta-lactamase_625_D161D,beta-lactamase_625_161,TEM-1,beta-lactamase_625,P62593,,YES,161,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.891,-0.891,,,0.341,,A,0.75,-0.52,4.655,,61.19,HAB,-0.961333,0.213352,0.000897697,0.589859 beta-lactamase_625_D174D,beta-lactamase_625_174,TEM-1,beta-lactamase_625,P62593,,YES,174,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.738,-0.738,,,0.238,,B,0.75,-0.1,,,,PAA,-1.91233,0.213352,0.00125633,0.66479 beta-lactamase_625_D177D,beta-lactamase_625_177,TEM-1,beta-lactamase_625,P62593,,YES,177,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.967,-0.967,,,0.006,T,L,0.75,-1.02,1.333,,64.69,BAP,-0.873667,0.213352,0.000864022,0.42418 beta-lactamase_625_D207D,beta-lactamase_625_207,TEM-1,beta-lactamase_625,P62593,,YES,207,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.064,-2.064,,,0.409,H,A,0.75,0.12,1.975,,77.62,HAH,-1.77033,0.213352,0.00592942,0.847578 beta-lactamase_625_D212D,beta-lactamase_625_212,TEM-1,beta-lactamase_625,P62593,,YES,212,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.624,-1.624,,,0.037,,b,0.75,-0.58,1.516,,74.48,HAB,-1.77667,0.213352,0.00644302,0.716148 beta-lactamase_625_D231D,beta-lactamase_625_231,TEM-1,beta-lactamase_625,P62593,,YES,231,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-0.816,-0.816,,,,E,B,0.75,-1.06,1.025,,65.38,HAB,-0.994,0.213352,0.00107395,0.468703 beta-lactamase_625_D252D,beta-lactamase_625_252,TEM-1,beta-lactamase_625,P62593,,YES,252,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.94,-1.94,,,0.766,,B,1.59,1.16,5.07,,67.83,OAO,-2.0965,0.213352,0.00575769,0.878138 beta-lactamase_625_D271D,beta-lactamase_625_271,TEM-1,beta-lactamase_625,P62593,,YES,271,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.249,-1.249,,,0.085,H,A,0.45,-0.05,,,63.99,HAA,-1.36633,0.213352,0.00752082,0.770352 beta-lactamase_625_D33D,beta-lactamase_625_33,TEM-1,beta-lactamase_625,P62593,,YES,33,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.321,-2.321,,,0.366,H,A,0.75,0.33,2.032,,77.62,BAH,-2.12133,0.213352,0.00435556,0.864255 beta-lactamase_625_D36D,beta-lactamase_625_36,TEM-1,beta-lactamase_625,P62593,,YES,36,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.732,-2.732,,,0.555,H,A,0.75,1.17,2.26,,77.62,AAP,-1.91167,0.213352,0.00476483,0.873794 beta-lactamase_625_D48D,beta-lactamase_625_48,TEM-1,beta-lactamase_625,P62593,,YES,48,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.101,-1.101,,,0.189,E,B,0.75,0.21,1.281,,50.35,HAH,-1.62467,0.213352,0.0027273,0.629098 beta-lactamase_625_D83D,beta-lactamase_625_83,TEM-1,beta-lactamase_625,P62593,,YES,83,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.066,-1.066,,,0.354,H,A,0.75,0.22,0.239,,48.95,HAH,-1.34733,0.213352,0.00205968,0.604808 beta-lactamase_625_D99D,beta-lactamase_625_99,TEM-1,beta-lactamase_625,P62593,,YES,99,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.191,-1.191,,,0.402,G,A,0.75,0.36,1.318,,64.69,PAH,-1.794,0.213352,0.00305446,0.714917 beta-lactamase_625_E102E,beta-lactamase_625_102,TEM-1,beta-lactamase_625,P62593,,YES,102,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.118,-2.118,,,0.722,S,B,1.04,1.82,1.336,,73.08,HAH,-1.581,0.213352,0.00486633,0.868155 beta-lactamase_625_E108E,beta-lactamase_625_108,TEM-1,beta-lactamase_625,P62593,,YES,108,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.46,-1.46,,,0.572,G,A,1.04,1.87,20.151,20.151,72.73,PAB,-1.437,0.213352,0.00413372,0.894049 beta-lactamase_625_E119E,beta-lactamase_625_119,TEM-1,beta-lactamase_625,P62593,,YES,119,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.412,-1.412,,,0.358,H,A,1.04,0.51,1.034,,63.99,BAH,-1.623,0.213352,0.00386966,0.660503 beta-lactamase_625_E145E,beta-lactamase_625_145,TEM-1,beta-lactamase_625,P62593,,YES,145,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.357,-2.357,,,0.545,H,A,1.04,0.79,2.64,,77.62,BAH,-2.069,0.213352,0.00553285,0.890477 beta-lactamase_625_E164E,beta-lactamase_625_164,TEM-1,beta-lactamase_625,P62593,,YES,164,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-0.948,-0.948,,,0.011,T,B,1.04,-0.4,1.321,,64.69,HAO,-1.388,0.213352,0.00137286,0.394565 beta-lactamase_625_E166E,beta-lactamase_625_166,TEM-1,beta-lactamase_625,P62593,,YES,166,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.756,-1.756,,,0.508,G,A,1.04,1.05,2.124,,73.08,OAH,-1.42233,0.213352,0.00512989,0.887847 beta-lactamase_625_E169E,beta-lactamase_625_169,TEM-1,beta-lactamase_625,P62593,,YES,169,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.23,-1.23,,,0.337,,A,1.04,1,1.806,,73.08,PAH,-1.16533,0.213352,0.00400994,0.736797 beta-lactamase_625_E175E,beta-lactamase_625_175,TEM-1,beta-lactamase_625,P62593,,YES,175,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.336,-2.336,,,0.551,,A,1.04,1.05,8.527,8.527,77.62,AAB,-1.31233,0.213352,0.00482205,0.892426 beta-lactamase_625_E195E,beta-lactamase_625_195,TEM-1,beta-lactamase_625,P62593,,YES,195,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.186,-2.186,,,1.016,S,A,1.04,0.85,2.043,,77.62,OAH,-2.02,0.213352,0.00496565,0.872933 beta-lactamase_625_E210E,beta-lactamase_625_210,TEM-1,beta-lactamase_625,P62593,,YES,210,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.319,-2.319,,,0.476,H,A,1.04,0.75,1.555,,77.62,HAH,-1.88567,0.213352,0.00663582,0.859428 beta-lactamase_625_E238E,beta-lactamase_625_238,TEM-1,beta-lactamase_625,P62593,,YES,238,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.002,-2.002,,,0.564,T,L,0.16,1.09,,,72.73,OAB,-1.4105,0.213352,0.00743256,0.837937 beta-lactamase_625_E26E,beta-lactamase_625_26,TEM-1,beta-lactamase_625,P62593,,YES,26,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.454,-2.454,,,0.54,H,A,1.04,0.98,19.42,19.42,93.01,OAP,-1.96167,0.213352,0.00297948,0.901676 beta-lactamase_625_E272E,beta-lactamase_625_272,TEM-1,beta-lactamase_625,P62593,,YES,272,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.127,-1.127,,,0.081,H,A,0.43,-0.97,,,63.64,AAB,-1.56333,0.213352,0.00545371,0.678026 beta-lactamase_625_E279E,beta-lactamase_625_279,TEM-1,beta-lactamase_625,P62593,,YES,279,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.038,-1.038,,,,H,A,0.75,-0.97,,,62.59,HAH,-1.36467,0.213352,0.0192826,0.595557 beta-lactamase_625_E35E,beta-lactamase_625_35,TEM-1,beta-lactamase_625,P62593,,YES,35,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-0.869,-0.869,,,0.15,H,A,1.04,0.21,0.664,,46.85,HAA,-1.88667,0.213352,0.00174441,0.623485 beta-lactamase_625_E46E,beta-lactamase_625_46,TEM-1,beta-lactamase_625,P62593,,YES,46,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.94,-1.94,,,0.021,E,B,1.04,0.14,1.453,,59.44,HAH,-2.079,0.213352,0.00427568,0.750915 beta-lactamase_625_E56E,beta-lactamase_625_56,TEM-1,beta-lactamase_625,P62593,,YES,56,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.043,-2.043,,,0.198,E,B,1.04,0.31,2.022,,72.73,HAP,-1.94033,0.213352,0.00238534,0.813528 beta-lactamase_625_E61E,beta-lactamase_625_61,TEM-1,beta-lactamase_625,P62593,,YES,61,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.115,-2.115,,,0.775,T,a,1.04,1.29,1.975,,77.62,OAA,-1.92567,0.213352,0.00440955,0.887421 beta-lactamase_625_E62E,beta-lactamase_625_62,TEM-1,beta-lactamase_625,P62593,,YES,62,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.193,-1.193,,,0.342,S,B,1.04,-0.3,2.124,,73.08,AAB,-1.417,0.213352,0.00264802,0.744841 beta-lactamase_625_E87E,beta-lactamase_625_87,TEM-1,beta-lactamase_625,P62593,,YES,87,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.421,-1.421,,,0.048,,B,1.04,0.92,17.923,17.923,64.69,PAP,-1.969,0.213352,0.00337888,0.780918 beta-lactamase_625_F149F,beta-lactamase_625_149,TEM-1,beta-lactamase_625,P62593,,YES,149,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.299,-1.299,,,0.195,H,A,0.58,0.11,1.863,,63.99,HHH,-1.46067,0.213352,0.00418462,0.756624 beta-lactamase_625_F228F,beta-lactamase_625_228,TEM-1,beta-lactamase_625,P62593,,YES,228,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-2.342,-2.342,,,0.154,E,B,0.58,-0.42,22.142,22.142,63.29,HHH,-1.53033,0.213352,0.0046669,0.823197 beta-lactamase_625_F58F,beta-lactamase_625_58,TEM-1,beta-lactamase_625,P62593,,YES,58,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-2.914,-2.914,,,0.266,E,B,0.58,-0.07,1.466,,77.62,PHB,-2.059,0.213352,0.00523369,0.841695 beta-lactamase_625_F64F,beta-lactamase_625_64,TEM-1,beta-lactamase_625,P62593,,YES,64,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-0.841,-0.841,,,0.006,E,B,0.58,-0.95,,,,BHO,-0.892667,0.213352,0.000947691,0.499702 beta-lactamase_625_F70F,beta-lactamase_625_70,TEM-1,beta-lactamase_625,P62593,,YES,70,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.169,-1.169,,,,H,A,0.58,-1.34,1.14,,63.99,PHB,-0.980667,0.213352,0.00193499,0.800398 beta-lactamase_625_G114G,beta-lactamase_625_114,TEM-1,beta-lactamase_625,P62593,,YES,114,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.094,-1.094,,,0.011,,p,0.29,0.35,2.148,,41.61,AOH,-1.43733,0.213352,0.00224919,0.773635 beta-lactamase_625_G141G,beta-lactamase_625_141,TEM-1,beta-lactamase_625,P62593,,YES,141,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.828,-0.828,,,0.575,T,l,0.29,-0.28,0.198,,64.69,HOO,-1.08933,0.213352,0.0012419,0.708807 beta-lactamase_625_G142G,beta-lactamase_625_142,TEM-1,beta-lactamase_625,P62593,,YES,142,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.707,-0.707,,,0.034,,p,0.29,-0.64,1.35,,64.69,OOO,-0.834,0.213352,0.00060149,0.695569 beta-lactamase_625_G154G,beta-lactamase_625_154,TEM-1,beta-lactamase_625,P62593,,YES,154,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.823,-0.823,,,0.54,T,l,0.29,-0.56,2.283,,64.69,HOA,-1.635,0.213352,0.00180205,0.701507 beta-lactamase_625_G194G,beta-lactamase_625_194,TEM-1,beta-lactamase_625,P62593,,YES,194,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.396,-1.396,,,0.276,S,b,0.29,0.36,3.593,,67.83,POA,-1.832,0.213352,0.00392163,0.800174 beta-lactamase_625_G216G,beta-lactamase_625_216,TEM-1,beta-lactamase_625,P62593,,YES,216,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.477,-1.477,,,0.437,I,A,0.29,-0.58,1.718,,74.48,HOO,-1.68067,0.213352,0.00639568,0.879081 beta-lactamase_625_G226G,beta-lactamase_625_226,TEM-1,beta-lactamase_625,P62593,,YES,226,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.461,-1.461,,,0.701,T,l,0.29,-0.25,3.199,,74.48,HOH,-1.42933,0.213352,0.00665294,0.867991 beta-lactamase_625_G234G,beta-lactamase_625_234,TEM-1,beta-lactamase_625,P62593,,YES,234,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.62,-0.62,,,0.023,E,B,0.29,-0.86,,,,POH,-1.25733,0.213352,0.000889577,0.661478 beta-lactamase_625_G236G,beta-lactamase_625_236,TEM-1,beta-lactamase_625,P62593,,YES,236,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.784,-0.784,,,0.241,,b,0.29,-0.59,3.506,,64.69,HOO,-1.025,0.213352,0.00162372,0.64699 beta-lactamase_625_G240G,beta-lactamase_625_240,TEM-1,beta-lactamase_625,P62593,,YES,240,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.537,-1.537,,,,,B,0.02,-0.74,,,65.38,BOP,-1.263,0.213352,0.00591201,0.786228 beta-lactamase_625_G243G,beta-lactamase_625_243,TEM-1,beta-lactamase_625,P62593,,YES,243,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.532,-1.532,,,,E,B,0.77,-1.24,,,50,BOH,-1.46867,0.213352,0.00464034,0.581169 beta-lactamase_625_G249G,beta-lactamase_625_249,TEM-1,beta-lactamase_625,P62593,,YES,249,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.312,-1.312,,,0.256,S,B,0.23,0.04,,,72.73,HOO,-1.81367,0.213352,0.00220169,0.75629 beta-lactamase_625_G253G,beta-lactamase_625_253,TEM-1,beta-lactamase_625,P62593,,YES,253,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-2.253,-2.253,,,0.308,,B,0.23,-0.46,,,73.08,AOB,-2.10633,0.213352,0.00786358,0.846265 beta-lactamase_625_G265G,beta-lactamase_625_265,TEM-1,beta-lactamase_625,P62593,,YES,265,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-2.58,-2.58,,,1.116,,A,0.35,1.17,,,69.58,POP,-1.978,0.213352,0.00811926,0.844556 beta-lactamase_625_G281G,beta-lactamase_625_281,TEM-1,beta-lactamase_625,P62593,,YES,281,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-2.247,-2.247,,,0.128,H,A,0.02,-0.26,,,77.62,HOH,-1.847,0.213352,0.0406482,0.812474 beta-lactamase_625_G39G,beta-lactamase_625_39,TEM-1,beta-lactamase_625,P62593,,YES,39,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.864,-1.864,,,0.701,T,L,0.29,0.47,29.926,29.926,77.62,HOH,-1.53633,0.213352,0.00487611,0.893741 beta-lactamase_625_G43G,beta-lactamase_625_43,TEM-1,beta-lactamase_625,P62593,,YES,43,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.62,-0.62,,,,E,B,0.29,-0.78,,,,HOH,-1.577,0.213352,0.00120151,0.598754 beta-lactamase_625_G52G,beta-lactamase_625_52,TEM-1,beta-lactamase_625,P62593,,YES,52,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.149,-1.149,,,0.299,,l,0.29,-0.04,2.103,,64.69,POB,-1.66267,0.213352,0.00340138,0.73092 beta-lactamase_625_G76G,beta-lactamase_625_76,TEM-1,beta-lactamase_625,P62593,,YES,76,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.189,-1.189,,,,H,A,0.29,-0.67,3.059,,67.83,OOH,-1.22267,0.213352,0.00476637,0.799783 beta-lactamase_625_G85G,beta-lactamase_625_85,TEM-1,beta-lactamase_625,P62593,,YES,85,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.011,-1.011,,,0.805,T,l,0.29,1.7,1.468,,63.64,HOP,-1.68733,0.213352,0.00252173,0.733342 beta-lactamase_625_G90G,beta-lactamase_625_90,TEM-1,beta-lactamase_625,P62593,,YES,90,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-2.091,-2.091,,,0.598,T,A,0.29,0.32,0.319,,77.62,HOB,-1.52633,0.213352,0.00490273,0.843238 beta-lactamase_625_H110H,beta-lactamase_625_110,TEM-1,beta-lactamase_625,P62593,,YES,110,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-1.706,-1.706,,,0.341,G,a,0.17,1.08,31.31,31.31,64.69,BBH,-1.73333,0.213352,0.00441499,0.891471 beta-lactamase_625_H151H,beta-lactamase_625_151,TEM-1,beta-lactamase_625,P62593,,YES,151,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-2.96,-2.96,,,0.594,H,A,0.17,0.1,1.843,,77.62,HBP,-2.34767,0.213352,0.00216946,0.87602 beta-lactamase_625_H156H,beta-lactamase_625_156,TEM-1,beta-lactamase_625,P62593,,YES,156,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-3.156,-3.156,,,0.753,S,A,0.17,-0.6,4.627,,77.62,ABH,-1.932,0.213352,0.00468596,0.90472 beta-lactamase_625_H24H,beta-lactamase_625_24,TEM-1,beta-lactamase_625,P62593,,YES,24,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-2.481,-2.481,,,,,,,,2.708,,93.01,OBO,-2.0035,0.213352,0.00238894,0.878448 beta-lactamase_625_H287H,beta-lactamase_625_287,TEM-1,beta-lactamase_625,P62593,,YES,287,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,,,,,,,,,,,,,BBH,-1.111,0.213352,,0.846642 beta-lactamase_625_H94H,beta-lactamase_625_94,TEM-1,beta-lactamase_625,P62593,,YES,94,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-2.5,-2.5,,,0.776,,B,0.17,1.24,19.42,19.42,77.62,HBH,-1.872,0.213352,0.00389226,0.89977 beta-lactamase_625_I125I,beta-lactamase_625_125,TEM-1,beta-lactamase_625,P62593,,YES,125,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.441,-1.441,,,,H,A,0.48,-0.7,2.034,,63.29,HHP,-1.248,0.213352,0.00383964,0.811049 beta-lactamase_625_I140I,beta-lactamase_625_140,TEM-1,beta-lactamase_625,P62593,,YES,140,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.733,-1.733,,,0.128,H,A,0.48,0.41,1.628,,73.08,PHO,-1.48733,0.213352,0.00597777,0.804338 beta-lactamase_625_I171I,beta-lactamase_625_171,TEM-1,beta-lactamase_625,P62593,,YES,171,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-2.431,-2.431,,,0.361,,B,0.48,0.53,3.869,,77.62,HHO,-1.55533,0.213352,0.00623355,0.88811 beta-lactamase_625_I206I,beta-lactamase_625_206,TEM-1,beta-lactamase_625,P62593,,YES,206,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-2.429,-2.429,,,0.173,H,A,0.48,-0.34,2.061,,77.62,HHA,-1.805,0.213352,0.00528934,0.883339 beta-lactamase_625_I229I,beta-lactamase_625_229,TEM-1,beta-lactamase_625,P62593,,YES,229,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.267,-1.267,,,0.083,E,B,0.48,-0.76,1.69,,50,HHH,-1.58767,0.213352,0.00477249,0.770564 beta-lactamase_625_I244I,beta-lactamase_625_244,TEM-1,beta-lactamase_625,P62593,,YES,244,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.555,-1.555,,,,E,B,0.48,-0.84,2.061,,77.62,OHH,-1.385,0.213352,0.00605379,0.7331 beta-lactamase_625_I245I,beta-lactamase_625_245,TEM-1,beta-lactamase_625,P62593,,YES,245,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.068,-1.068,,,,E,B,0.48,-0.92,,,64.69,HHH,-1.58133,0.213352,0.00391032,0.743966 beta-lactamase_625_I258I,beta-lactamase_625_258,TEM-1,beta-lactamase_625,P62593,,YES,258,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.975,-1.975,,,,E,B,0.04,-1.02,,,67.83,BHH,-1.67667,0.213352,0.007931,0.686004 beta-lactamase_625_I261I,beta-lactamase_625_261,TEM-1,beta-lactamase_625,P62593,,YES,261,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-2.88,-2.88,,,0.014,E,B,0.7,-0.39,,,77.62,HHH,-1.771,0.213352,0.0123091,0.711858 beta-lactamase_625_I277I,beta-lactamase_625_277,TEM-1,beta-lactamase_625,P62593,,YES,277,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.869,-1.869,,,0.545,H,A,1.52,-0.01,,,77.62,PHH,-1.45367,0.213352,0.0169305,0.837431 beta-lactamase_625_I280I,beta-lactamase_625_280,TEM-1,beta-lactamase_625,P62593,,YES,280,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.708,-1.708,,,0.379,H,A,0.48,-0.72,,,68.18,AHO,-1.66433,0.213352,0.0530888,0.873969 beta-lactamase_625_I285I,beta-lactamase_625_285,TEM-1,beta-lactamase_625,P62593,,YES,285,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.845,-1.845,,,0.312,T,a,0.65,0.64,,,72.73,HHB,-1.64567,0.213352,0.101555,0.835025 beta-lactamase_625_I45I,beta-lactamase_625_45,TEM-1,beta-lactamase_625,P62593,,YES,45,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-2.421,-2.421,,,,E,B,0.48,-0.3,3.642,,77.62,HHA,-2.30267,0.213352,0.00452842,0.777313 beta-lactamase_625_I54I,beta-lactamase_625_54,TEM-1,beta-lactamase_625,P62593,,YES,54,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-2.838,-2.838,,,0.669,E,B,0.48,-0.14,3.946,,73.78,BHH,-2.337,0.213352,0.00403589,0.877357 beta-lactamase_625_I93I,beta-lactamase_625_93,TEM-1,beta-lactamase_625,P62593,,YES,93,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.401,-1.401,,,0.128,E,B,0.48,0.44,1.524,,67.83,BHB,-1.873,0.213352,0.00527066,0.718472 beta-lactamase_625_K109K,beta-lactamase_625_109,TEM-1,beta-lactamase_625,P62593,,YES,109,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.734,-1.734,,,0.787,G,A,2.34,2.21,7.243,,72.73,ABB,-1.63333,0.213352,0.00462493,0.909782 beta-lactamase_625_K144K,beta-lactamase_625_144,TEM-1,beta-lactamase_625,P62593,,YES,144,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-2.388,-2.388,,,0.863,H,A,2.34,1.27,2.313,,77.62,OBA,-1.904,0.213352,0.00481141,0.909978 beta-lactamase_625_K190K,beta-lactamase_625_190,TEM-1,beta-lactamase_625,P62593,,YES,190,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.994,-1.994,,,0.371,H,A,2.34,0.16,29.753,29.753,77.62,BBH,-1.64167,0.213352,0.00574527,0.917886 beta-lactamase_625_K213K,beta-lactamase_625_213,TEM-1,beta-lactamase_625,P62593,,YES,213,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.81,-1.81,,,0.67,,A,2.34,0.29,3.924,,67.83,ABH,-1.57767,0.213352,0.00610411,0.902496 beta-lactamase_625_K232K,beta-lactamase_625_232,TEM-1,beta-lactamase_625,P62593,,YES,232,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.012,-1.012,,,,E,B,2.34,-1.1,1.992,,65.03,ABP,-1.238,0.213352,0.00313441,0.426833 beta-lactamase_625_K254K,beta-lactamase_625_254,TEM-1,beta-lactamase_625,P62593,,YES,254,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-2.126,-2.126,,,0.312,,a,2.07,-0.48,,,69.58,OBO,-2.215,0.213352,0.00369,0.869124 beta-lactamase_625_K286K,beta-lactamase_625_286,TEM-1,beta-lactamase_625,P62593,,YES,286,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.111,-1.111,,,0.492,,?,2.81,0.6,,,,HBB,-1.478,0.213352,,0.726966 beta-lactamase_625_K30K,beta-lactamase_625_30,TEM-1,beta-lactamase_625,P62593,,YES,30,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-2.307,-2.307,,,0.142,H,A,2.34,-0.65,2.434,,93.01,HBH,-2.32833,0.213352,0.00448593,0.807975 beta-lactamase_625_K32K,beta-lactamase_625_32,TEM-1,beta-lactamase_625,P62593,,YES,32,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.984,-1.984,,,0.563,H,A,2.34,0.34,1.754,,73.08,HBA,-2.04233,0.213352,0.00401283,0.886964 beta-lactamase_625_K53K,beta-lactamase_625_53,TEM-1,beta-lactamase_625,P62593,,YES,53,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-2.313,-2.313,,,0.589,,B,2.34,1.15,19.72,19.72,77.62,OBH,-2.1,0.213352,0.00383383,0.90045 beta-lactamase_625_K71K,beta-lactamase_625_71,TEM-1,beta-lactamase_625,P62593,,YES,71,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-0.8,-0.8,,,,H,A,2.34,-0.99,,,,HBH,-1.209,0.213352,0.00103192,0.463394 beta-lactamase_625_L100L,beta-lactamase_625_100,TEM-1,beta-lactamase_625,P62593,,YES,100,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.218,-1.218,,,0.343,,B,0.55,0.13,1.173,,63.29,AHH,-1.23467,0.213352,0.00413885,0.711712 beta-lactamase_625_L111L,beta-lactamase_625_111,TEM-1,beta-lactamase_625,P62593,,YES,111,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.76,-1.76,,,0.328,T,A,0.55,0.93,2.26,,64.34,BHP,-1.884,0.213352,0.00480671,0.896521 beta-lactamase_625_L120L,beta-lactamase_625_120,TEM-1,beta-lactamase_625,P62593,,YES,120,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.044,-1.044,,,,H,A,0.55,-1.13,7.813,,64.69,AHO,-1.13633,0.213352,0.00143563,0.65803 beta-lactamase_625_L135L,beta-lactamase_625_135,TEM-1,beta-lactamase_625,P62593,,YES,135,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.002,-1.002,,,0.117,H,A,0.55,-0.58,0.697,,43.71,PHH,-1.03767,0.213352,0.00244423,0.821609 beta-lactamase_625_L136L,beta-lactamase_625_136,TEM-1,beta-lactamase_625,P62593,,YES,136,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.232,-1.232,,,,H,A,0.55,-0.34,0.336,,48.95,HHH,-1.088,0.213352,0.00442304,0.7894 beta-lactamase_625_L137L,beta-lactamase_625_137,TEM-1,beta-lactamase_625,P62593,,YES,137,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.03,-1.03,,,,H,A,0.55,-0.38,1.5,,42.31,HHP,-1.58933,0.213352,0.00278599,0.837385 beta-lactamase_625_L146L,beta-lactamase_625_146,TEM-1,beta-lactamase_625,P62593,,YES,146,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.462,-1.462,,,0.007,H,A,0.55,-0.56,2.16,,64.69,AHP,-1.656,0.213352,0.00474542,0.780437 beta-lactamase_625_L150L,beta-lactamase_625_150,TEM-1,beta-lactamase_625,P62593,,YES,150,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.326,-1.326,,,,H,A,0.55,-0.2,1.615,,62.94,HHB,-1.86167,0.213352,0.00463171,0.828835 beta-lactamase_625_L160L,beta-lactamase_625_160,TEM-1,beta-lactamase_625,P62593,,YES,160,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.977,-0.977,,,0.022,,B,0.55,-0.6,0.237,,44.41,BHA,-0.936,0.213352,0.00193775,0.822936 beta-lactamase_625_L167L,beta-lactamase_625_167,TEM-1,beta-lactamase_625,P62593,,YES,167,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.138,-1.138,,,0.015,G,A,0.55,-0.63,1.344,,64.69,AHP,-1.30767,0.213352,0.00303566,0.817921 beta-lactamase_625_L188L,beta-lactamase_625_188,TEM-1,beta-lactamase_625,P62593,,YES,188,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.166,-1.166,,,,H,A,0.55,-0.3,2.982,,60.14,PHB,-1.47033,0.213352,0.00295687,0.845073 beta-lactamase_625_L191L,beta-lactamase_625_191,TEM-1,beta-lactamase_625,P62593,,YES,191,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.087,-1.087,,,,H,A,0.55,0.09,1.908,,63.29,BHH,-1.445,0.213352,0.00263549,0.840137 beta-lactamase_625_L192L,beta-lactamase_625_192,TEM-1,beta-lactamase_625,P62593,,YES,192,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.254,-1.254,,,0.095,H,A,0.55,0.35,1.748,,60.14,HHP,-1.41833,0.213352,0.00558728,0.804847 beta-lactamase_625_L196L,beta-lactamase_625_196,TEM-1,beta-lactamase_625,P62593,,YES,196,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-2.478,-2.478,,,0.518,S,A,0.55,1.35,12.152,12.152,77.62,AHH,-1.839,0.213352,0.00512144,0.913213 beta-lactamase_625_L197L,beta-lactamase_625_197,TEM-1,beta-lactamase_625,P62593,,YES,197,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.853,-0.853,,,0.007,S,B,0.55,0.33,1.756,,60.14,HHP,-1.833,0.213352,0.00144602,0.676902 beta-lactamase_625_L199L,beta-lactamase_625_199,TEM-1,beta-lactamase_625,P62593,,YES,199,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-2.942,-2.942,,,0.832,H,A,0.55,0.42,1.552,,77.62,PHH,-2.32933,0.213352,0.0048649,0.903839 beta-lactamase_625_L205L,beta-lactamase_625_205,TEM-1,beta-lactamase_625,P62593,,YES,205,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.922,-0.922,,,,H,A,0.55,-0.46,3.782,,42.31,PHH,-1.57767,0.213352,0.00255802,0.778263 beta-lactamase_625_L218L,beta-lactamase_625_218,TEM-1,beta-lactamase_625,P62593,,YES,218,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.391,-1.391,,,,I,b,0.55,-0.53,17.202,17.202,74.48,OHH,-1.58867,0.213352,0.00618274,0.733868 beta-lactamase_625_L219L,beta-lactamase_625_219,TEM-1,beta-lactamase_625,P62593,,YES,219,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.313,-1.313,,,,I,A,0.55,-0.51,5.627,,74.48,HHB,-1.21533,0.213352,0.00664345,0.760605 beta-lactamase_625_L223L,beta-lactamase_625_223,TEM-1,beta-lactamase_625,P62593,,YES,223,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.055,-1.055,,,0.27,,B,0.55,0.09,1.633,,74.48,HHO,-1.35033,0.213352,0.00372793,0.69798 beta-lactamase_625_L248L,beta-lactamase_625_248,TEM-1,beta-lactamase_625,P62593,,YES,248,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.794,-1.794,,,,E,b,0.84,-0.43,,,61.19,HHO,-1.52867,0.213352,0.00428493,0.630613 beta-lactamase_625_L284L,beta-lactamase_625_284,TEM-1,beta-lactamase_625,P62593,,YES,284,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.981,-1.981,,,0.848,H,A,2.89,0.67,,,77.62,PHH,-1.82133,0.213352,0.0686156,0.855222 beta-lactamase_625_L28L,beta-lactamase_625_28,TEM-1,beta-lactamase_625,P62593,,YES,28,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.579,-1.579,,,0.277,H,A,0.55,-0.16,2.716,,93.01,PHH,-2.11333,0.213352,0.00359321,0.896031 beta-lactamase_625_L38L,beta-lactamase_625_38,TEM-1,beta-lactamase_625,P62593,,YES,38,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.343,-1.343,,,0.088,H,A,0.55,0.2,1.986,,64.34,PHO,-1.78033,0.213352,0.00373244,0.847216 beta-lactamase_625_L47L,beta-lactamase_625_47,TEM-1,beta-lactamase_625,P62593,,YES,47,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.876,-1.876,,,0.007,E,B,0.55,0.2,1.244,,67.83,AHA,-1.639,0.213352,0.00439844,0.754006 beta-lactamase_625_L49L,beta-lactamase_625_49,TEM-1,beta-lactamase_625,P62593,,YES,49,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.897,-1.897,,,0.131,T,A,0.55,0.04,3.112,,64.69,AHP,-1.99233,0.213352,0.00401477,0.857406 beta-lactamase_625_L55L,beta-lactamase_625_55,TEM-1,beta-lactamase_625,P62593,,YES,55,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.86,-1.86,,,0.372,E,A,0.55,-0.36,1.423,,63.99,HHA,-2.247,0.213352,0.00403741,0.866474 beta-lactamase_625_L73L,beta-lactamase_625_73,TEM-1,beta-lactamase_625,P62593,,YES,73,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.507,-1.507,,,,H,A,0.55,-0.64,2.933,,67.83,HHH,-1.487,0.213352,0.00488983,0.825186 beta-lactamase_625_L74L,beta-lactamase_625_74,TEM-1,beta-lactamase_625,P62593,,YES,74,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.296,-1.296,,,,H,A,0.55,-0.91,0.895,,50,HHO,-1.34933,0.213352,0.00493255,0.815299 beta-lactamase_625_L79L,beta-lactamase_625_79,TEM-1,beta-lactamase_625,P62593,,YES,79,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-0.842,-0.842,,,0.007,H,A,0.55,-0.16,0.935,,50.35,HHP,-1.44333,0.213352,0.000947397,0.658993 beta-lactamase_625_L89L,beta-lactamase_625_89,TEM-1,beta-lactamase_625,P62593,,YES,89,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.096,-1.096,,,0.168,T,A,0.55,0.63,1.599,,64.34,PHO,-1.75767,0.213352,0.00207068,0.701169 beta-lactamase_625_M115M,beta-lactamase_625_115,TEM-1,beta-lactamase_625,P62593,,YES,115,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.389,-1.389,,,0.019,E,B,0.55,0.08,0.739,,69.58,OHP,-1.25433,0.213352,0.0034337,0.785298 beta-lactamase_625_M127M,beta-lactamase_625_127,TEM-1,beta-lactamase_625,P62593,,YES,127,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-2.251,-2.251,,,0.312,S,A,0.55,0.32,1.671,,72.73,PHP,-1.40433,0.213352,0.00437927,0.897745 beta-lactamase_625_M153M,beta-lactamase_625_153,TEM-1,beta-lactamase_625,P62593,,YES,153,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-3.193,-3.193,,,0.14,T,A,0.55,-0.11,2.061,,77.62,PHO,-2.25767,0.213352,0.00509109,0.868388 beta-lactamase_625_M180M,beta-lactamase_625_180,TEM-1,beta-lactamase_625,P62593,,YES,180,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-2.795,-2.795,,,0.242,,B,0.55,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.213352,0.00552048,0.906157 beta-lactamase_625_M184M,beta-lactamase_625_184,TEM-1,beta-lactamase_625,P62593,,YES,184,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.593,-1.593,,,,H,A,0.55,-0.87,2.765,,62.94,HHH,-1.41,0.213352,0.00356019,0.828019 beta-lactamase_625_M209M,beta-lactamase_625_209,TEM-1,beta-lactamase_625,P62593,,YES,209,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.442,-1.442,,,,H,A,0.55,-0.97,1.167,,64.69,HHA,-1.52633,0.213352,0.00625021,0.694437 beta-lactamase_625_M270M,beta-lactamase_625_270,TEM-1,beta-lactamase_625,P62593,,YES,270,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.723,-1.723,,,0.422,H,A,1.59,1.15,,,64.34,PHA,-1.70933,0.213352,0.00767762,0.854778 beta-lactamase_625_M66M,beta-lactamase_625_66,TEM-1,beta-lactamase_625,P62593,,YES,66,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.362,-1.362,,,0.013,,A,0.55,-0.7,1.659,,73.08,OHH,-1.49567,0.213352,0.00412876,0.801438 beta-lactamase_625_M67M,beta-lactamase_625_67,TEM-1,beta-lactamase_625,P62593,,YES,67,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-2.231,-2.231,,,0.006,G,P,0.55,-0.81,2.653,,65.03,HHP,-1.502,0.213352,0.00409753,0.804214 beta-lactamase_625_N130N,beta-lactamase_625_130,TEM-1,beta-lactamase_625,P62593,,YES,130,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-0.798,-0.798,,,0.069,H,A,0.61,-0.74,,,,APP,-0.980667,0.213352,0.000683376,0.671764 beta-lactamase_625_N134N,beta-lactamase_625_134,TEM-1,beta-lactamase_625,P62593,,YES,134,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-0.879,-0.879,,,0.138,H,A,0.61,-0.6,3.776,,53.15,HPH,-1.02233,0.213352,0.000644786,0.548606 beta-lactamase_625_N152N,beta-lactamase_625_152,TEM-1,beta-lactamase_625,P62593,,YES,152,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-2.757,-2.757,,,0.863,H,A,0.61,0.92,2.061,,77.62,BPH,-2.97,0.213352,0.00471429,0.904649 beta-lactamase_625_N168N,beta-lactamase_625_168,TEM-1,beta-lactamase_625,P62593,,YES,168,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-1.029,-1.029,,,0.113,G,A,0.61,-0.4,1.014,,44.41,HPA,-1.13233,0.213352,0.00288667,0.815439 beta-lactamase_625_N173N,beta-lactamase_625_173,TEM-1,beta-lactamase_625,P62593,,YES,173,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-2.663,-2.663,,,1.044,T,l,0.61,1.25,1.426,,77.62,OPA,-1.46633,0.213352,0.0033769,0.887261 beta-lactamase_625_N274N,beta-lactamase_625_274,TEM-1,beta-lactamase_625,P62593,,YES,274,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-2.082,-2.082,,,0.066,H,A,0.03,-0.27,,,64.69,BPB,-1.931,0.213352,0.0110418,0.780169 beta-lactamase_625_N50N,beta-lactamase_625_50,TEM-1,beta-lactamase_625,P62593,,YES,50,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-2.979,-2.979,,,0.912,T,A,0.61,1.24,3.446,,77.62,HPP,-2.134,0.213352,0.0047211,0.909143 beta-lactamase_625_N98N,beta-lactamase_625_98,TEM-1,beta-lactamase_625,P62593,,YES,98,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-2.973,-2.973,,,0.963,G,A,0.61,1.35,1.332,,77.62,PPA,-2.07867,0.213352,0.00505389,0.900971 beta-lactamase_625_P105P,beta-lactamase_625_105,TEM-1,beta-lactamase_625,P62593,,YES,105,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.813,-0.813,,,0.226,T,A,0.52,0.8,1.154,,63.29,POH,-1.01533,0.213352,0.0011981,0.443092 beta-lactamase_625_P143P,beta-lactamase_625_143,TEM-1,beta-lactamase_625,P62593,,YES,143,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.967,-0.967,,,0.075,H,A,0.52,-0.37,1.445,,66.78,OOB,-1.354,0.213352,0.00114551,0.514543 beta-lactamase_625_P165P,beta-lactamase_625_165,TEM-1,beta-lactamase_625,P62593,,YES,165,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.373,-1.373,,,0.203,T,A,0.52,-0.31,0.414,,73.78,AOA,-1.359,0.213352,0.00549538,0.484158 beta-lactamase_625_P172P,beta-lactamase_625_172,TEM-1,beta-lactamase_625,P62593,,YES,172,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.998,-0.998,,,0.639,T,b,0.52,0.24,4.386,,74.48,HOP,-2.03067,0.213352,0.00312594,0.63338 beta-lactamase_625_P181P,beta-lactamase_625_181,TEM-1,beta-lactamase_625,P62593,,YES,181,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.813,-0.813,,,,H,A,0.52,-1.14,1.797,,61.54,HOH,-1.795,0.213352,0.000703122,0.536715 beta-lactamase_625_P217P,beta-lactamase_625_217,TEM-1,beta-lactamase_625,P62593,,YES,217,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-2.062,-2.062,,,0.496,I,A,0.52,-0.33,1.087,,74.48,OOH,-1.64333,0.213352,0.00463211,0.645008 beta-lactamase_625_P224P,beta-lactamase_625_224,TEM-1,beta-lactamase_625,P62593,,YES,224,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.893,-0.893,,,0.383,,B,0.52,-0.3,1.35,,74.48,HOH,-1.26433,0.213352,0.00189564,0.487181 beta-lactamase_625_P250P,beta-lactamase_625_250,TEM-1,beta-lactamase_625,P62593,,YES,250,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-2.335,-2.335,,,0.89,T,L,0.23,1.53,,,66.08,OOO,-1.8235,0.213352,0.00550899,0.813376 beta-lactamase_625_P255P,beta-lactamase_625_255,TEM-1,beta-lactamase_625,P62593,,YES,255,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-2.266,-2.266,,,0.141,E,B,0.68,0.38,,,63.99,BOP,-2.00433,0.213352,0.00499612,0.497155 beta-lactamase_625_P25P,beta-lactamase_625_25,TEM-1,beta-lactamase_625,P62593,,YES,25,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.526,-1.526,,,0.624,H,A,0.52,0.14,14.584,14.584,73.08,BOA,-2.15367,0.213352,0.00347571,0.793963 beta-lactamase_625_P60P,beta-lactamase_625_60,TEM-1,beta-lactamase_625,P62593,,YES,60,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-2.469,-2.469,,,0.256,T,A,0.52,-0.56,3.653,,77.62,BOA,-1.97633,0.213352,0.00521318,0.672058 beta-lactamase_625_P65P,beta-lactamase_625_65,TEM-1,beta-lactamase_625,P62593,,YES,65,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-0.894,-0.894,,,0.098,E,B,0.52,-0.62,0.3,,40.56,HOH,-1.03233,0.213352,0.00152776,0.471798 beta-lactamase_625_Q203Q,beta-lactamase_625_203,TEM-1,beta-lactamase_625,P62593,,YES,203,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.168,-2.168,,,0.47,H,A,0.64,-0.38,1.66,,65.38,BPP,-1.614,0.213352,0.00631514,0.899194 beta-lactamase_625_Q204Q,beta-lactamase_625_204,TEM-1,beta-lactamase_625,P62593,,YES,204,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-1.382,-1.382,,,0.204,H,A,0.64,0.09,1.707,,66.08,PPH,-1.49067,0.213352,0.00364106,0.765123 beta-lactamase_625_Q267Q,beta-lactamase_625_267,TEM-1,beta-lactamase_625,P62593,,YES,267,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.308,-2.308,,,0.54,,B,0.42,-0.14,,,73.78,PPH,-1.9,0.213352,0.0102128,0.851328 beta-lactamase_625_Q276Q,beta-lactamase_625_276,TEM-1,beta-lactamase_625,P62593,,YES,276,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-1.144,-1.144,,,0.117,H,A,0.64,-0.84,,,44.06,BPH,-1.47,0.213352,0.0191712,0.843887 beta-lactamase_625_Q37Q,beta-lactamase_625_37,TEM-1,beta-lactamase_625,P62593,,YES,37,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.134,-2.134,,,0.613,H,A,0.64,1.98,1.318,,73.08,APH,-2.06967,0.213352,0.00425833,0.902851 beta-lactamase_625_Q86Q,beta-lactamase_625_86,TEM-1,beta-lactamase_625,P62593,,YES,86,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.4,-2.4,,,0.696,S,A,0.64,2.38,2.105,,77.62,OPA,-1.61067,0.213352,0.00450027,0.918281 beta-lactamase_625_Q88Q,beta-lactamase_625_88,TEM-1,beta-lactamase_625,P62593,,YES,88,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.086,-2.086,,,0.807,,B,0.64,2.03,1.84,,77.62,APH,-1.53433,0.213352,0.00504167,0.899097 beta-lactamase_625_Q97Q,beta-lactamase_625_97,TEM-1,beta-lactamase_625,P62593,,YES,97,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.072,-2.072,,,0.823,G,A,0.64,2.42,16.954,16.954,77.62,PPP,-2.43833,0.213352,0.0045116,0.910333 beta-lactamase_625_R118R,beta-lactamase_625_118,TEM-1,beta-lactamase_625,P62593,,YES,118,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.413,-2.413,,,0.457,H,A,1.2,1.39,2.144,,77.62,HBA,-1.785,0.213352,0.00538794,0.900566 beta-lactamase_625_R159R,beta-lactamase_625_159,TEM-1,beta-lactamase_625,P62593,,YES,159,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-0.94,-0.94,,,0.316,,B,1.2,-0.55,1.172,,64.34,PBH,-1.011,0.213352,0.00108472,0.686738 beta-lactamase_625_R162R,beta-lactamase_625_162,TEM-1,beta-lactamase_625,P62593,,YES,162,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.016,-1.016,,,0.124,S,B,1.2,-0.37,1.445,,64.69,ABH,-1.25,0.213352,0.000561334,0.667189 beta-lactamase_625_R176R,beta-lactamase_625_176,TEM-1,beta-lactamase_625,P62593,,YES,176,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-0.863,-0.863,,,0.385,T,B,1.2,-0.63,,,,ABA,-1.38867,0.213352,0.00105554,0.778185 beta-lactamase_625_R189R,beta-lactamase_625_189,TEM-1,beta-lactamase_625,P62593,,YES,189,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.844,-1.844,,,0.278,H,A,1.2,1.01,1.512,,72.73,HBB,-1.668,0.213352,0.0050699,0.882614 beta-lactamase_625_R202R,beta-lactamase_625_202,TEM-1,beta-lactamase_625,P62593,,YES,202,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.292,-1.292,,,0.188,H,A,1.2,0.62,1.918,,77.62,PBP,-1.54767,0.213352,0.00321899,0.748463 beta-lactamase_625_R220R,beta-lactamase_625_220,TEM-1,beta-lactamase_625,P62593,,YES,220,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-0.942,-0.942,,,0.295,I,A,1.2,-0.76,5.086,,74.48,HBP,-1.33633,0.213352,0.00232421,0.582635 beta-lactamase_625_R239R,beta-lactamase_625_239,TEM-1,beta-lactamase_625,P62593,,YES,239,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-0.819,-0.819,,,0.115,T,l,0.91,-0.62,,,42.31,ABO,-1.45267,0.213352,0.00213852,0.736129 beta-lactamase_625_R242R,beta-lactamase_625_242,TEM-1,beta-lactamase_625,P62593,,YES,242,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.319,-1.319,,,,E,B,0.91,-1.05,,,50,PBO,-1.428,0.213352,0.00452879,0.539522 beta-lactamase_625_R257R,beta-lactamase_625_257,TEM-1,beta-lactamase_625,P62593,,YES,257,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.533,-1.533,,,,E,B,1.64,-0.7,,,58.74,PBH,-1.70967,0.213352,0.00756629,0.490589 beta-lactamase_625_R273R,beta-lactamase_625_273,TEM-1,beta-lactamase_625,P62593,,YES,273,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.314,-2.314,,,0.564,H,A,1.2,1.57,1.455,,73.78,ABP,-1.841,0.213352,0.0077952,0.826967 beta-lactamase_625_R275R,beta-lactamase_625_275,TEM-1,beta-lactamase_625,P62593,,YES,275,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.397,-1.397,,,0.015,H,A,1.68,-0.52,,,62.59,PBP,-1.541,0.213352,0.0141984,0.559075 beta-lactamase_625_R41R,beta-lactamase_625_41,TEM-1,beta-lactamase_625,P62593,,YES,41,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-0.942,-0.942,,,0.321,E,B,1.2,-0.07,1.186,,65.03,HBH,-1.30267,0.213352,0.00123327,0.688116 beta-lactamase_625_R59R,beta-lactamase_625_59,TEM-1,beta-lactamase_625,P62593,,YES,59,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.345,-1.345,,,0.329,S,L,1.2,-0.09,2.995,,73.08,HBO,-2.24267,0.213352,0.00318082,0.605199 beta-lactamase_625_R63R,beta-lactamase_625_63,TEM-1,beta-lactamase_625,P62593,,YES,63,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-0.943,-0.943,,,0.218,,B,1.2,-0.31,0.677,,44.06,ABH,-0.992333,0.213352,0.00126938,0.691483 beta-lactamase_625_R81R,beta-lactamase_625_81,TEM-1,beta-lactamase_625,P62593,,YES,81,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.466,-1.466,,,0.218,H,A,1.2,1.66,1.236,,50,PBH,-1.60667,0.213352,0.00499763,0.829119 beta-lactamase_625_R91R,beta-lactamase_625_91,TEM-1,beta-lactamase_625,P62593,,YES,91,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.392,-1.392,,,0.444,,B,1.2,0.96,1.318,,50.35,OBB,-1.73367,0.213352,0.00380226,0.698224 beta-lactamase_625_R92R,beta-lactamase_625_92,TEM-1,beta-lactamase_625,P62593,,YES,92,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.718,-1.718,,,0.479,E,B,1.2,1.36,3.069,,65.38,BBH,-1.50367,0.213352,0.00429626,0.887133 beta-lactamase_625_S104S,beta-lactamase_625_104,TEM-1,beta-lactamase_625,P62593,,YES,104,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.015,-1.015,,,0.04,,b,0.27,0.57,1.76,,63.29,HPO,-1.05267,0.213352,0.00218083,0.824771 beta-lactamase_625_S122S,beta-lactamase_625_122,TEM-1,beta-lactamase_625,P62593,,YES,122,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.406,-2.406,,,0.352,H,A,0.27,-0.54,2.144,,77.62,OPH,-1.39767,0.213352,0.00497825,0.918225 beta-lactamase_625_S128S,beta-lactamase_625_128,TEM-1,beta-lactamase_625,P62593,,YES,128,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-0.84,-0.84,,,0.08,,L,0.27,-0.32,,,,HPA,-1.30233,0.213352,0.00071483,0.506 beta-lactamase_625_S201S,beta-lactamase_625_201,TEM-1,beta-lactamase_625,P62593,,YES,201,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.183,-1.183,,,0.064,H,A,0.27,-0.07,4.045,,64.69,HPB,-1.451,0.213352,0.00198815,0.854757 beta-lactamase_625_S221S,beta-lactamase_625_221,TEM-1,beta-lactamase_625,P62593,,YES,221,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.754,-1.754,,,0.624,H,A,0.27,-0.2,1.495,,74.48,BPH,-1.59967,0.213352,0.0046094,0.884355 beta-lactamase_625_S233S,beta-lactamase_625_233,TEM-1,beta-lactamase_625,P62593,,YES,233,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.886,-1.886,,,0.016,E,B,0.27,-1.01,1.773,,77.62,BPO,-1.17267,0.213352,0.00311415,0.696607 beta-lactamase_625_S241S,beta-lactamase_625_241,TEM-1,beta-lactamase_625,P62593,,YES,241,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.433,-1.433,,,0.094,E,B,0.93,-0.16,,,50,OPB,-1.42967,0.213352,0.00452736,0.801928 beta-lactamase_625_S256S,beta-lactamase_625_256,TEM-1,beta-lactamase_625,P62593,,YES,256,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.621,-1.621,,,,E,B,0.75,-0.84,,,73.08,OPB,-1.80667,0.213352,0.00710634,0.655872 beta-lactamase_625_S266S,beta-lactamase_625_266,TEM-1,beta-lactamase_625,P62593,,YES,266,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.369,-1.369,,,0.175,S,B,0.27,0.07,,,64.34,OPP,-2.08567,0.213352,0.0140785,0.796796 beta-lactamase_625_S283S,beta-lactamase_625_283,TEM-1,beta-lactamase_625,P62593,,YES,283,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.638,-1.638,,,0.165,H,A,0.75,0.04,,,69.23,HPH,-1.735,0.213352,0.0429138,0.819206 beta-lactamase_625_S51S,beta-lactamase_625_51,TEM-1,beta-lactamase_625,P62593,,YES,51,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.526,-1.526,,,0.496,T,A,0.27,0.26,1.699,,72.73,PPO,-1.88467,0.213352,0.00504821,0.870965 beta-lactamase_625_S57S,beta-lactamase_625_57,TEM-1,beta-lactamase_625,P62593,,YES,57,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.918,-1.918,,,0.352,E,B,0.27,-0.18,1.971,,72.73,APH,-2.29167,0.213352,0.00492804,0.854554 beta-lactamase_625_S68S,beta-lactamase_625_68,TEM-1,beta-lactamase_625,P62593,,YES,68,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-0.913,-0.913,,,0.064,G,A,0.27,-1.03,3.202,,64.69,HPP,-1.37233,0.213352,0.000800065,0.407648 beta-lactamase_625_S80S,beta-lactamase_625_80,TEM-1,beta-lactamase_625,P62593,,YES,80,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.029,-2.029,,,0.192,H,A,0.27,0.46,2.256,,77.62,HPB,-1.44567,0.213352,0.00565569,0.882929 beta-lactamase_625_S96S,beta-lactamase_625_96,TEM-1,beta-lactamase_625,P62593,,YES,96,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.27,-2.27,,,0.368,,b,0.27,0.39,5.244,,73.78,HPP,-2.019,0.213352,0.00551835,0.893333 beta-lactamase_625_T107T,beta-lactamase_625_107,TEM-1,beta-lactamase_625,P62593,,YES,107,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.117,-1.117,,,,G,A,0.22,-0.06,3.676,,67.83,HPA,-1.265,0.213352,0.00239347,0.833466 beta-lactamase_625_T112T,beta-lactamase_625_112,TEM-1,beta-lactamase_625,P62593,,YES,112,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.186,-2.186,,,0.921,T,A,0.22,1.06,1.581,,73.78,HPA,-1.925,0.213352,0.00531334,0.902928 beta-lactamase_625_T116T,beta-lactamase_625_116,TEM-1,beta-lactamase_625,P62593,,YES,116,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.28,-1.28,,,0.115,E,B,0.22,-0.12,0.343,,67.48,HPH,-1.39967,0.213352,0.00336175,0.824886 beta-lactamase_625_T126T,beta-lactamase_625_126,TEM-1,beta-lactamase_625,P62593,,YES,126,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.122,-1.122,,,0.05,H,A,0.22,-0.05,0.817,,44.41,HPH,-1.60467,0.213352,0.00244552,0.850028 beta-lactamase_625_T131T,beta-lactamase_625_131,TEM-1,beta-lactamase_625,P62593,,YES,131,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.328,-1.328,,,,H,A,0.22,-0.69,2.031,,67.48,PPH,-1.00867,0.213352,0.00345886,0.87055 beta-lactamase_625_T138T,beta-lactamase_625_138,TEM-1,beta-lactamase_625,P62593,,YES,138,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.506,-2.506,,,0.662,H,A,0.22,-0.03,1.626,,73.78,HPP,-1.81233,0.213352,0.00487868,0.906225 beta-lactamase_625_T139T,beta-lactamase_625_139,TEM-1,beta-lactamase_625,P62593,,YES,139,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.901,-1.901,,,0.216,H,A,0.22,0.39,2.256,,77.62,PPH,-2.04667,0.213352,0.00441837,0.895018 beta-lactamase_625_T147T,beta-lactamase_625_147,TEM-1,beta-lactamase_625,P62593,,YES,147,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.149,-1.149,,,0.281,H,A,0.22,-0.68,2.838,,64.34,HPH,-1.456,0.213352,0.00226017,0.703904 beta-lactamase_625_T158T,beta-lactamase_625_158,TEM-1,beta-lactamase_625,P62593,,YES,158,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.116,-1.116,,,0.036,,B,0.22,-0.85,3.771,,69.58,HPB,-1.269,0.213352,0.00341825,0.79474 beta-lactamase_625_T178T,beta-lactamase_625_178,TEM-1,beta-lactamase_625,P62593,,YES,178,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-0.791,-0.791,,,0.029,E,B,0.22,-1.07,,,,APP,-0.947667,0.213352,0.000684366,0.629066 beta-lactamase_625_T179T,beta-lactamase_625_179,TEM-1,beta-lactamase_625,P62593,,YES,179,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.085,-1.085,,,,E,B,0.22,-1.38,0.367,,73.08,PPH,-1.557,0.213352,0.00226045,0.652448 beta-lactamase_625_T186T,beta-lactamase_625_186,TEM-1,beta-lactamase_625,P62593,,YES,186,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.522,-2.522,,,0.396,H,A,0.22,-0.28,0.515,,77.62,HPP,-1.77633,0.213352,0.00485034,0.897369 beta-lactamase_625_T187T,beta-lactamase_625_187,TEM-1,beta-lactamase_625,P62593,,YES,187,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.401,-1.401,,,0.007,H,A,0.22,-1.19,1.751,,67.48,PPH,-1.69633,0.213352,0.00491782,0.801216 beta-lactamase_625_T193T,beta-lactamase_625_193,TEM-1,beta-lactamase_625,P62593,,YES,193,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.914,-1.914,,,0.439,H,a,0.22,0.33,1.863,,63.99,HPO,-1.52133,0.213352,0.00482669,0.903541 beta-lactamase_625_T198T,beta-lactamase_625_198,TEM-1,beta-lactamase_625,P62593,,YES,198,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.168,-2.168,,,0.489,,B,0.22,-0.13,0.37,,73.78,HPH,-1.98767,0.213352,0.004311,0.796276 beta-lactamase_625_T263T,beta-lactamase_625_263,TEM-1,beta-lactamase_625,P62593,,YES,263,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.031,-2.031,,,0.517,S,l,0.07,0.31,,,77.62,HPP,-1.78267,0.213352,0.0110582,0.826996 beta-lactamase_625_T264T,beta-lactamase_625_264,TEM-1,beta-lactamase_625,P62593,,YES,264,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.985,-1.985,,,0.04,,B,0.05,0.29,,,73.78,PPO,-2.19867,0.213352,0.0119399,0.791159 beta-lactamase_625_T269T,beta-lactamase_625_269,TEM-1,beta-lactamase_625,P62593,,YES,269,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.156,-2.156,,,0.646,H,A,0.53,0.4,,,77.62,HPH,-1.96733,0.213352,0.00950944,0.85855 beta-lactamase_625_T27T,beta-lactamase_625_27,TEM-1,beta-lactamase_625,P62593,,YES,27,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.905,-1.905,,,0.007,H,A,0.22,-0.37,3.72,,93.01,APH,-1.97933,0.213352,0.00306559,0.817918 beta-lactamase_625_T69T,beta-lactamase_625_69,TEM-1,beta-lactamase_625,P62593,,YES,69,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-0.973,-0.973,,,,G,A,0.22,-1.24,2.716,,93.01,PPH,-1.01833,0.213352,0.00127498,0.573428 beta-lactamase_625_V101V,beta-lactamase_625_101,TEM-1,beta-lactamase_625,P62593,,YES,101,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.295,-1.295,,,0.342,,B,0.44,0,1.675,,73.08,HHA,-1.54367,0.213352,0.00374492,0.74671 beta-lactamase_625_V106V,beta-lactamase_625_106,TEM-1,beta-lactamase_625,P62593,,YES,106,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.218,-1.218,,,0.258,T,A,0.44,0.24,1.188,,72.73,OHP,-1.04933,0.213352,0.00304168,0.781449 beta-lactamase_625_V117V,beta-lactamase_625_117,TEM-1,beta-lactamase_625,P62593,,YES,117,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.53,-1.53,,,,H,A,0.44,-0.34,1.23,,65.03,PHB,-1.741,0.213352,0.00467906,0.790914 beta-lactamase_625_V157V,beta-lactamase_625_157,TEM-1,beta-lactamase_625,P62593,,YES,157,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.751,-1.751,,,0.308,S,a,0.44,-0.75,1.847,,69.58,BHP,-2.00767,0.213352,0.00506849,0.904948 beta-lactamase_625_V214V,beta-lactamase_625_214,TEM-1,beta-lactamase_625,P62593,,YES,214,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.299,-1.299,,,0.375,S,A,0.44,-0.44,1.899,,74.48,BHH,-1.53733,0.213352,0.00628442,0.737668 beta-lactamase_625_V259V,beta-lactamase_625_259,TEM-1,beta-lactamase_625,P62593,,YES,259,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.522,-1.522,,,,E,B,0.04,-0.8,,,64.34,HHH,-1.53267,0.213352,0.0070773,0.778971 beta-lactamase_625_V260V,beta-lactamase_625_260,TEM-1,beta-lactamase_625,P62593,,YES,260,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.101,-1.101,,,,E,B,0.23,-1.04,,,60.49,HHH,-1.83433,0.213352,0.00471757,0.696973 beta-lactamase_625_V29V,beta-lactamase_625_29,TEM-1,beta-lactamase_625,P62593,,YES,29,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-2.856,-2.856,,,0.733,H,A,0.44,-0.78,1.931,,93.01,HHB,-2.24733,0.213352,0.00318969,0.918432 beta-lactamase_625_V31V,beta-lactamase_625_31,TEM-1,beta-lactamase_625,P62593,,YES,31,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.822,-1.822,,,,H,A,0.44,-0.46,2.576,,73.78,BHB,-2.03767,0.213352,0.00478065,0.76517 beta-lactamase_625_V42V,beta-lactamase_625_42,TEM-1,beta-lactamase_625,P62593,,YES,42,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.564,-1.564,,,0.017,E,B,0.44,-0.51,2.576,,63.99,BHO,-1.042,0.213352,0.00404515,0.773794 beta-lactamase_625_V72V,beta-lactamase_625_72,TEM-1,beta-lactamase_625,P62593,,YES,72,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.658,-1.658,,,,H,A,0.44,-1.03,0.981,,65.73,BHH,-1.32167,0.213352,0.00501194,0.755642 beta-lactamase_625_V78V,beta-lactamase_625_78,TEM-1,beta-lactamase_625,P62593,,YES,78,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.459,-1.459,,,,H,A,0.44,-0.47,2.045,,63.64,HHH,-1.17833,0.213352,0.00492501,0.79757 beta-lactamase_625_V82V,beta-lactamase_625_82,TEM-1,beta-lactamase_625,P62593,,YES,82,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.325,-1.325,,,0.267,H,A,0.44,0.08,1.379,,93.01,BHA,-1.28567,0.213352,0.00397046,0.749934 beta-lactamase_625_W163W,beta-lactamase_625_163,TEM-1,beta-lactamase_625,P62593,,YES,163,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-1.843,-1.843,,,0.467,,B,0.47,-0.5,5.019,,63.99,BHA,-1.269,0.213352,0.00418955,0.909525 beta-lactamase_625_W208W,beta-lactamase_625_208,TEM-1,beta-lactamase_625,P62593,,YES,208,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-0.818,-0.818,,,0.067,H,A,0.47,-0.65,,,,AHH,-1.44133,0.213352,0.00126609,0.585934 beta-lactamase_625_W227W,beta-lactamase_625_227,TEM-1,beta-lactamase_625,P62593,,YES,227,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-0.982,-0.982,,,0.272,,B,0.47,-0.29,2.533,,74.48,OHH,-1.595,0.213352,0.00226019,0.41018 beta-lactamase_625_W288W,beta-lactamase_625_288,TEM-1,beta-lactamase_625,P62593,,YES,288,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,,,,,,,,,,,,,BHO,,0.213352,,0.642714 beta-lactamase_625_Y103Y,beta-lactamase_625_103,TEM-1,beta-lactamase_625,P62593,,YES,103,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-1.33,-1.33,,,0.613,S,l,0.21,1.21,5.721,,63.29,AHP,-1.48767,0.213352,0.00443048,0.743506 beta-lactamase_625_Y262Y,beta-lactamase_625_262,TEM-1,beta-lactamase_625,P62593,,YES,262,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-1.332,-1.332,,,0.108,E,B,0.43,-0.55,,,67.83,HHP,-2.081,0.213352,0.00853516,0.665737 beta-lactamase_625_Y44Y,beta-lactamase_625_44,TEM-1,beta-lactamase_625,P62593,,YES,44,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-2.547,-2.547,,,,E,B,0.21,-0.45,2.371,,73.78,OHH,-1.86267,0.213352,0.00426364,0.603695 beta-lactamase_625_Y95Y,beta-lactamase_625_95,TEM-1,beta-lactamase_625,P62593,,YES,95,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-1.715,-1.715,,,0.122,,b,0.21,-0.37,3.355,,77.62,BHP,-2.16167,0.213352,0.00479449,0.632939 beta-lactamase_A123F,beta-lactamase_123,TEM-1,beta-lactamase,P62593,,YES,123,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.834,-4.065,3.231,4.70061,0.039,H,A,0.52,-0.72,0.705,,41.26,PHH,-1.47367,0.221079,0.0010157,0.489172 beta-lactamase_A123Q,beta-lactamase_123,TEM-1,beta-lactamase,P62593,,YES,123,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.834,-3.948,3.114,4.70061,0.039,H,A,0.52,-0.72,0.705,,41.26,PHH,-1.47367,0.221079,0.0010157,0.481004 beta-lactamase_A123W,beta-lactamase_123,TEM-1,beta-lactamase,P62593,,YES,123,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.834,-5.348,4.514,4.70061,0.039,H,A,0.52,-0.72,0.705,,41.26,PHH,-1.47367,0.221079,0.0010157,0.492653 beta-lactamase_A124W,beta-lactamase_124,TEM-1,beta-lactamase,P62593,,YES,124,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.181,-5.322,4.141,4.58507,,H,A,0.58,-0.9,2.273,,64.34,HHH,-1.152,0.221079,0.00481399,0.534739 beta-lactamase_A132D,beta-lactamase_132,TEM-1,beta-lactamase,P62593,,YES,132,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-0.9,-3.706,2.806,4.58504,,H,A,2.34,-0.93,2.217,,64.69,PHH,-1.138,0.221079,0.000962524,0.195335 beta-lactamase_A132F,beta-lactamase_132,TEM-1,beta-lactamase,P62593,,YES,132,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-0.9,-4.091,3.191,4.58504,,H,A,2.34,-0.93,2.217,,64.69,PHH,-1.138,0.221079,0.000962524,0.226206 beta-lactamase_A132H,beta-lactamase_132,TEM-1,beta-lactamase,P62593,,YES,132,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.9,-4.724,3.824,4.58504,,H,A,2.34,-0.93,2.217,,64.69,PHH,-1.138,0.221079,0.000962524,0.219875 beta-lactamase_A132I,beta-lactamase_132,TEM-1,beta-lactamase,P62593,,YES,132,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.9,-3.489,2.589,4.58504,,H,A,2.34,-0.93,2.217,,64.69,PHH,-1.138,0.221079,0.000962524,0.231836 beta-lactamase_A132N,beta-lactamase_132,TEM-1,beta-lactamase,P62593,,YES,132,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.9,-3.872,2.972,4.58504,,H,A,2.34,-0.93,2.217,,64.69,PHH,-1.138,0.221079,0.000962524,0.250718 beta-lactamase_A132Q,beta-lactamase_132,TEM-1,beta-lactamase,P62593,,YES,132,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-0.9,-3.943,3.043,4.58504,,H,A,2.34,-0.93,2.217,,64.69,PHH,-1.138,0.221079,0.000962524,0.264837 beta-lactamase_A132W,beta-lactamase_132,TEM-1,beta-lactamase,P62593,,YES,132,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-0.9,-5.372,4.472,4.58504,,H,A,2.34,-0.93,2.217,,64.69,PHH,-1.138,0.221079,0.000962524,0.227518 beta-lactamase_A132Y,beta-lactamase_132,TEM-1,beta-lactamase,P62593,,YES,132,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.9,-4.186,3.286,4.58504,,H,A,2.34,-0.93,2.217,,64.69,PHH,-1.138,0.221079,0.000962524,0.224619 beta-lactamase_A133K,beta-lactamase_133,TEM-1,beta-lactamase,P62593,,YES,133,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.186,-3.614,2.428,4.86423,,H,A,0.55,-0.86,2.649,,67.83,HHP,-0.988333,0.221079,0.00468022,0.510859 beta-lactamase_A133M,beta-lactamase_133,TEM-1,beta-lactamase,P62593,,YES,133,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.186,-4.694,3.508,4.86423,,H,A,0.55,-0.86,2.649,,67.83,HHP,-0.988333,0.221079,0.00468022,0.580161 beta-lactamase_A133W,beta-lactamase_133,TEM-1,beta-lactamase,P62593,,YES,133,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.186,-5.303,4.117,4.86423,,H,A,0.55,-0.86,2.649,,67.83,HHP,-0.988333,0.221079,0.00468022,0.515504 beta-lactamase_A133Y,beta-lactamase_133,TEM-1,beta-lactamase,P62593,,YES,133,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.186,-4.319,3.133,4.86423,,H,A,0.55,-0.86,2.649,,67.83,HHP,-0.988333,0.221079,0.00468022,0.53779 beta-lactamase_A16F,beta-lactamase_16,TEM-1,beta-lactamase,P62593,,YES,16,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,,-4.161,2.226,,,,,,,,,,HHH,,0.221079,0.00245392,0.5359 beta-lactamase_A16N,beta-lactamase_16,TEM-1,beta-lactamase,P62593,,YES,16,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,,-2.759,0.824,,,,,,,,,,HHH,,0.221079,0.00245392,0.707471 beta-lactamase_A16W,beta-lactamase_16,TEM-1,beta-lactamase,P62593,,YES,16,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,,-5.319,3.384,,,,,,,,,,HHH,,0.221079,0.00245392,0.562076 beta-lactamase_A185F,beta-lactamase_185,TEM-1,beta-lactamase,P62593,,YES,185,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.406,-4.091,2.685,4.89877,,H,A,2.34,-1.02,2.999,,65.03,HHP,-1.84033,0.221079,0.00467449,0.219351 beta-lactamase_A185H,beta-lactamase_185,TEM-1,beta-lactamase,P62593,,YES,185,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.406,-4.889,3.483,4.89877,,H,A,2.34,-1.02,2.999,,65.03,HHP,-1.84033,0.221079,0.00467449,0.2171 beta-lactamase_A185M,beta-lactamase_185,TEM-1,beta-lactamase,P62593,,YES,185,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.406,-4.39,2.984,4.89877,,H,A,2.34,-1.02,2.999,,65.03,HHP,-1.84033,0.221079,0.00467449,0.259308 beta-lactamase_A185W,beta-lactamase_185,TEM-1,beta-lactamase,P62593,,YES,185,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.406,-5.387,3.981,4.89877,,H,A,2.34,-1.02,2.999,,65.03,HHP,-1.84033,0.221079,0.00467449,0.22394 beta-lactamase_A225W,beta-lactamase_225,TEM-1,beta-lactamase,P62593,,YES,225,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.845,-5.541,3.696,6.5181,1,T,B,0.58,-0.38,4.077,,74.48,OHO,-1.39967,0.221079,0.00465057,0.870049 beta-lactamase_A235M,beta-lactamase_235,TEM-1,beta-lactamase,P62593,,YES,235,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.266,-4.612,3.346,4.83024,0.32,E,B,0.52,-0.86,1.344,,50,OHO,-0.89,0.221079,0.00493474,0.640133 beta-lactamase_A23F,beta-lactamase_23,TEM-1,beta-lactamase,P62593,,YES,23,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.548,-2.544,0.996,,,,,,,0.801,,93.01,HHB,-2.235,0.221079,0.00245563,0.769702 beta-lactamase_A23H,beta-lactamase_23,TEM-1,beta-lactamase,P62593,,YES,23,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.548,-4.69,3.142,,,,,,,0.801,,93.01,HHB,-2.235,0.221079,0.00245563,0.838705 beta-lactamase_A23I,beta-lactamase_23,TEM-1,beta-lactamase,P62593,,YES,23,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.548,-3.704,2.156,,,,,,,0.801,,93.01,HHB,-2.235,0.221079,0.00245563,0.822801 beta-lactamase_A23L,beta-lactamase_23,TEM-1,beta-lactamase,P62593,,YES,23,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.548,-3.277,1.729,,,,,,,0.801,,93.01,HHB,-2.235,0.221079,0.00245563,0.802903 beta-lactamase_A23M,beta-lactamase_23,TEM-1,beta-lactamase,P62593,,YES,23,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.548,-4.566,3.018,,,,,,,0.801,,93.01,HHB,-2.235,0.221079,0.00245563,0.850453 beta-lactamase_A23Q,beta-lactamase_23,TEM-1,beta-lactamase,P62593,,YES,23,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.548,-4.038,2.49,,,,,,,0.801,,93.01,HHB,-2.235,0.221079,0.00245563,0.818186 beta-lactamase_A245A,beta-lactamase_245,TEM-1,beta-lactamase,P62593,,YES,245,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.068,-1.068,,4.78972,,E,B,0.17,-0.92,0.831,,64.69,HHH,-1.58133,0.221079,0.00391032,0.738129 beta-lactamase_A266A,beta-lactamase_266,TEM-1,beta-lactamase,P62593,,YES,266,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.369,-1.369,,5.02057,0.175,S,B,0.52,0.07,1.832,,64.34,PHP,-2.08567,0.221079,0.0140785,0.725969 beta-lactamase_A276A,beta-lactamase_276,TEM-1,beta-lactamase,P62593,,YES,276,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.144,-1.144,,5.1387,0.117,H,A,0.52,-0.84,1.283,,44.06,HHA,-1.47,0.221079,0.0191712,0.805793 beta-lactamase_A276M,beta-lactamase_276,TEM-1,beta-lactamase,P62593,,YES,276,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.144,-4.502,3.358,5.1387,0.117,H,A,0.52,-0.84,1.283,,44.06,HHA,-1.47,0.221079,0.0191712,0.718924 beta-lactamase_A276W,beta-lactamase_276,TEM-1,beta-lactamase,P62593,,YES,276,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.144,-5.395,4.251,5.1387,0.117,H,A,0.52,-0.84,1.283,,44.06,HHA,-1.47,0.221079,0.0191712,0.641567 beta-lactamase_A280A,beta-lactamase_280,TEM-1,beta-lactamase,P62593,,YES,280,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.708,-1.708,,4.74932,0.379,H,A,0.52,-0.72,1.785,,68.18,OHP,-1.66433,0.221079,0.0530888,0.866259 beta-lactamase_A34M,beta-lactamase_34,TEM-1,beta-lactamase,P62593,,YES,34,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-2.059,-4.351,2.292,4.9129,,H,A,0.75,-0.54,3.614,,73.78,AHA,-1.74967,0.221079,0.00407913,0.777731 beta-lactamase_A34W,beta-lactamase_34,TEM-1,beta-lactamase,P62593,,YES,34,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.059,-2.89,0.831,4.9129,,H,A,0.75,-0.54,3.614,,73.78,AHA,-1.74967,0.221079,0.00407913,0.7424 beta-lactamase_A77I,beta-lactamase_77,TEM-1,beta-lactamase,P62593,,YES,77,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.234,-3.583,2.349,4.75777,0.039,H,A,0.52,-0.56,1.708,,64.34,OHH,-1.294,0.221079,0.00282362,0.821069 beta-lactamase_A84W,beta-lactamase_84,TEM-1,beta-lactamase,P62593,,YES,84,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.651,-5.52,3.869,5.28927,0.65,T,A,0.52,0.96,1.863,,68.18,AHO,-1.24267,0.221079,0.00503822,0.866448 beta-lactamase_A9W,beta-lactamase_9,TEM-1,beta-lactamase,P62593,,YES,9,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-2.147,-5.221,3.074,,,,,,,5.128,,72.73,HHH,-2.04267,0.221079,0.00247263,0.753252 beta-lactamase_C18A,beta-lactamase_18,TEM-1,beta-lactamase,P62593,,YES,18,C,A,CA,Special,Hydrophobic,5.07,6,0.93,195,121,89,-32,108.5,88.6,-19.9,-2.26,-2.065,-0.195,,,,,,,3.995,,93.01,HOH,-2.093,0.221079,0.002536,0.848408 beta-lactamase_C18D,beta-lactamase_18,TEM-1,beta-lactamase,P62593,,YES,18,C,D,CD,Special,negativeCharge,5.07,5.0516,-0.0184,154,121,133,12,108.5,111.1,2.6,-2.26,-3.602,1.342,,,,,,,3.995,,93.01,HOH,-2.093,0.221079,0.002536,0.768735 beta-lactamase_C18E,beta-lactamase_18,TEM-1,beta-lactamase,P62593,,YES,18,C,E,CE,Special,negativeCharge,5.07,3.22,-1.85,170,121,147,26,108.5,138.4,29.9,-2.26,-2.733,0.473,,,,,,,3.995,,93.01,HOH,-2.093,0.221079,0.002536,0.803715 beta-lactamase_C18H,beta-lactamase_18,TEM-1,beta-lactamase,P62593,,YES,18,C,H,CH,Special,PositiveCharge,5.07,7.59,2.52,174,121,155,34,108.5,153.2,44.7,-2.26,-4.739,2.479,,,,,,,3.995,,93.01,HOH,-2.093,0.221079,0.002536,0.767175 beta-lactamase_C18M,beta-lactamase_18,TEM-1,beta-lactamase,P62593,,YES,18,C,M,CM,Special,Hydrophobic,5.07,5.74,0.67,196,121,149,28,108.5,162.9,54.4,-2.26,-4.659,2.399,,,,,,,3.995,,93.01,HOH,-2.093,0.221079,0.002536,0.768403 beta-lactamase_C18N,beta-lactamase_18,TEM-1,beta-lactamase,P62593,,YES,18,C,N,CN,Special,Polar,5.07,5.47157,0.401575,139,121,132,11,108.5,114.1,5.6,-2.26,-3.819,1.559,,,,,,,3.995,,93.01,HOH,-2.093,0.221079,0.002536,0.781803 beta-lactamase_C18Q,beta-lactamase_18,TEM-1,beta-lactamase,P62593,,YES,18,C,Q,CQ,Special,Polar,5.07,6.24429,1.17429,154,121,146,25,108.5,143.8,35.3,-2.26,-3.991,1.731,,,,,,,3.995,,93.01,HOH,-2.093,0.221079,0.002536,0.779608 beta-lactamase_D155K,beta-lactamase_155,TEM-1,beta-lactamase,P62593,,YES,155,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-0.889,-3.426,2.537,4.92265,0.049,,B,0.45,-0.9,3.208,,64.69,OAB,-1.62267,0.221079,0.00135315,0.29487 beta-lactamase_D155W,beta-lactamase_155,TEM-1,beta-lactamase,P62593,,YES,155,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.889,-5.571,4.682,4.92265,0.049,,B,0.45,-0.9,3.208,,64.69,OAB,-1.62267,0.221079,0.00135315,0.319383 beta-lactamase_D250D,beta-lactamase_250,TEM-1,beta-lactamase,P62593,,YES,250,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.335,-2.335,,5.72026,0.89,T,L,0.23,1.53,24.737,24.737,66.08,OAO,-1.85133,0.221079,0.00550899,0.844864 beta-lactamase_D269D,beta-lactamase_269,TEM-1,beta-lactamase,P62593,,YES,269,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.156,-2.156,,5.47645,0.646,H,A,0.23,0.4,21.796,21.796,77.62,HAA,-1.96733,0.221079,0.00950944,0.840039 beta-lactamase_D33M,beta-lactamase_33,TEM-1,beta-lactamase,P62593,,YES,33,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.321,-4.607,2.286,5.05203,0.366,H,A,0.23,0.33,2.032,,77.62,BAH,-2.12133,0.221079,0.00435556,0.883 beta-lactamase_D33W,beta-lactamase_33,TEM-1,beta-lactamase,P62593,,YES,33,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.321,-5.495,3.174,5.05203,0.366,H,A,0.23,0.33,2.032,,77.62,BAH,-2.12133,0.221079,0.00435556,0.877532 beta-lactamase_D36M,beta-lactamase_36,TEM-1,beta-lactamase,P62593,,YES,36,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.732,-4.763,2.031,5.39764,0.555,H,A,0.11,1.17,13.689,13.689,77.62,AAP,-1.91167,0.221079,0.00476483,0.900123 beta-lactamase_E102F,beta-lactamase_102,TEM-1,beta-lactamase,P62593,,YES,102,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.118,-4.365,2.247,6.36157,0.722,S,B,1.5,1.82,1.336,,73.08,HAH,-1.581,0.221079,0.00486633,0.883182 beta-lactamase_E102H,beta-lactamase_102,TEM-1,beta-lactamase,P62593,,YES,102,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.118,-3.309,1.191,6.36157,0.722,S,B,1.5,1.82,1.336,,73.08,HAH,-1.581,0.221079,0.00486633,0.886313 beta-lactamase_E102I,beta-lactamase_102,TEM-1,beta-lactamase,P62593,,YES,102,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.118,-4.045,1.927,6.36157,0.722,S,B,1.5,1.82,1.336,,73.08,HAH,-1.581,0.221079,0.00486633,0.872743 beta-lactamase_E102W,beta-lactamase_102,TEM-1,beta-lactamase,P62593,,YES,102,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.118,-5.479,3.361,6.36157,0.722,S,B,1.5,1.82,1.336,,73.08,HAH,-1.581,0.221079,0.00486633,0.880881 beta-lactamase_E102Y,beta-lactamase_102,TEM-1,beta-lactamase,P62593,,YES,102,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.118,-4.321,2.203,6.36157,0.722,S,B,1.5,1.82,1.336,,73.08,HAH,-1.581,0.221079,0.00486633,0.879414 beta-lactamase_E108M,beta-lactamase_108,TEM-1,beta-lactamase,P62593,,YES,108,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.46,-4.775,3.315,5.52079,0.572,G,A,0.52,1.87,1.973,,72.73,PAB,-1.437,0.221079,0.00413372,0.870708 beta-lactamase_E119P,beta-lactamase_119,TEM-1,beta-lactamase,P62593,,YES,119,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.412,-3.828,2.416,5.33349,0.358,H,A,1.52,0.51,1.983,,63.99,BAH,-1.623,0.221079,0.00386966,0.50727 beta-lactamase_E164C,beta-lactamase_164,TEM-1,beta-lactamase,P62593,,YES,164,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-0.948,-5.311,4.363,5.3334,0.011,T,B,1.62,-0.4,1.055,,64.69,HAO,-1.388,0.221079,0.00137286,0.304964 beta-lactamase_E164I,beta-lactamase_164,TEM-1,beta-lactamase,P62593,,YES,164,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-0.948,-4.08,3.132,5.3334,0.011,T,B,1.62,-0.4,1.055,,64.69,HAO,-1.388,0.221079,0.00137286,0.226234 beta-lactamase_E164L,beta-lactamase_164,TEM-1,beta-lactamase,P62593,,YES,164,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-0.948,-3.627,2.679,5.3334,0.011,T,B,1.62,-0.4,1.055,,64.69,HAO,-1.388,0.221079,0.00137286,0.223972 beta-lactamase_E164Q,beta-lactamase_164,TEM-1,beta-lactamase,P62593,,YES,164,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-0.948,-3.358,2.41,5.3334,0.011,T,B,1.62,-0.4,1.055,,64.69,HAO,-1.388,0.221079,0.00137286,0.321355 beta-lactamase_E164W,beta-lactamase_164,TEM-1,beta-lactamase,P62593,,YES,164,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-0.948,-5.346,4.398,5.3334,0.011,T,B,1.62,-0.4,1.055,,64.69,HAO,-1.388,0.221079,0.00137286,0.244598 beta-lactamase_E169M,beta-lactamase_169,TEM-1,beta-lactamase,P62593,,YES,169,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.23,-4.676,3.446,5.78896,0.337,,A,0.52,1,1.806,,73.08,PAH,-1.16533,0.221079,0.00400994,0.779366 beta-lactamase_E195F,beta-lactamase_195,TEM-1,beta-lactamase,P62593,,YES,195,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.186,-4.475,2.289,7.28489,1.016,S,A,1.52,0.85,2.583,,77.62,OAH,-2.02,0.221079,0.00496565,0.833024 beta-lactamase_E195M,beta-lactamase_195,TEM-1,beta-lactamase,P62593,,YES,195,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.186,-4.856,2.67,7.28489,1.016,S,A,1.52,0.85,2.583,,77.62,OAH,-2.02,0.221079,0.00496565,0.856097 beta-lactamase_E195P,beta-lactamase_195,TEM-1,beta-lactamase,P62593,,YES,195,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.186,-2.83,0.644,7.28489,1.016,S,A,1.52,0.85,2.583,,77.62,OAH,-2.02,0.221079,0.00496565,0.912721 beta-lactamase_E210W,beta-lactamase_210,TEM-1,beta-lactamase,P62593,,YES,210,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.319,-5.437,3.118,5.7398,0.476,H,A,0.52,0.75,1.555,,77.62,HAH,-1.88567,0.221079,0.00663582,0.881858 beta-lactamase_E237E,beta-lactamase_237,TEM-1,beta-lactamase,P62593,,YES,237,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.058,-2.058,,5.42877,0.583,S,B,1.62,1.2,2.144,,77.62,OAB,-1.61467,0.221079,0.0048626,0.852855 beta-lactamase_E26C,beta-lactamase_26,TEM-1,beta-lactamase,P62593,,YES,26,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.454,-5.02,2.566,,0.54,H,A,1.04,0.98,,,93.01,OAP,-1.96167,0.221079,0.00297948,0.854009 beta-lactamase_E26F,beta-lactamase_26,TEM-1,beta-lactamase,P62593,,YES,26,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.454,-4.297,1.843,,0.54,H,A,1.04,0.98,,,93.01,OAP,-1.96167,0.221079,0.00297948,0.833792 beta-lactamase_E26H,beta-lactamase_26,TEM-1,beta-lactamase,P62593,,YES,26,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-2.454,-4.609,2.155,,0.54,H,A,1.04,0.98,,,93.01,OAP,-1.96167,0.221079,0.00297948,0.853229 beta-lactamase_E26M,beta-lactamase_26,TEM-1,beta-lactamase,P62593,,YES,26,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.454,-4.568,2.114,,0.54,H,A,1.04,0.98,,,93.01,OAP,-1.96167,0.221079,0.00297948,0.853313 beta-lactamase_E26N,beta-lactamase_26,TEM-1,beta-lactamase,P62593,,YES,26,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.454,-3.711,1.257,,0.54,H,A,1.04,0.98,,,93.01,OAP,-1.96167,0.221079,0.00297948,0.843429 beta-lactamase_E26P,beta-lactamase_26,TEM-1,beta-lactamase,P62593,,YES,26,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-2.454,-2.862,0.408,,0.54,H,A,1.04,0.98,,,93.01,OAP,-1.96167,0.221079,0.00297948,0.822874 beta-lactamase_E26S,beta-lactamase_26,TEM-1,beta-lactamase,P62593,,YES,26,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.454,-3.34,0.886,,0.54,H,A,1.04,0.98,,,93.01,OAP,-1.96167,0.221079,0.00297948,0.854374 beta-lactamase_E26W,beta-lactamase_26,TEM-1,beta-lactamase,P62593,,YES,26,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.454,-5.402,2.948,,0.54,H,A,1.04,0.98,,,93.01,OAP,-1.96167,0.221079,0.00297948,0.854697 beta-lactamase_E26Y,beta-lactamase_26,TEM-1,beta-lactamase,P62593,,YES,26,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.454,-4.272,1.818,,0.54,H,A,1.04,0.98,,,93.01,OAP,-1.96167,0.221079,0.00297948,0.840801 beta-lactamase_E270E,beta-lactamase_270,TEM-1,beta-lactamase,P62593,,YES,270,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.723,-1.723,,5.33196,0.422,H,A,0.52,1.15,1.745,,64.34,AAB,-1.70933,0.221079,0.00767762,0.828294 beta-lactamase_E277E,beta-lactamase_277,TEM-1,beta-lactamase,P62593,,YES,277,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.869,-1.869,,5.51786,0.545,H,A,0.52,-0.01,2.022,,77.62,HAH,-1.45367,0.221079,0.0169305,0.82327 beta-lactamase_E46M,beta-lactamase_46,TEM-1,beta-lactamase,P62593,,YES,46,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.94,-4.375,2.435,5.36461,0.021,E,B,1.51,0.14,0.373,,59.44,HAH,-2.079,0.221079,0.00427568,0.71641 beta-lactamase_E46P,beta-lactamase_46,TEM-1,beta-lactamase,P62593,,YES,46,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.94,-4.039,2.099,5.36461,0.021,E,B,1.51,0.14,0.373,,59.44,HAH,-2.079,0.221079,0.00427568,0.443698 beta-lactamase_E46Y,beta-lactamase_46,TEM-1,beta-lactamase,P62593,,YES,46,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.94,-4.198,2.258,5.36461,0.021,E,B,1.51,0.14,0.373,,59.44,HAH,-2.079,0.221079,0.00427568,0.65096 beta-lactamase_E62M,beta-lactamase_62,TEM-1,beta-lactamase,P62593,,YES,62,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.193,-4.77,3.577,5.93066,0.342,S,B,1.52,-0.3,3.139,,73.08,AAB,-1.417,0.221079,0.00264802,0.74118 beta-lactamase_E62P,beta-lactamase_62,TEM-1,beta-lactamase,P62593,,YES,62,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.193,-3.775,2.582,5.93066,0.342,S,B,1.52,-0.3,3.139,,73.08,AAB,-1.417,0.221079,0.00264802,0.516765 beta-lactamase_E62W,beta-lactamase_62,TEM-1,beta-lactamase,P62593,,YES,62,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.193,-5.409,4.216,5.93066,0.342,S,B,1.52,-0.3,3.139,,73.08,AAB,-1.417,0.221079,0.00264802,0.733304 beta-lactamase_F17M,beta-lactamase_17,TEM-1,beta-lactamase,P62593,,YES,17,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-2.337,-2.727,0.39,,,,,,,2.192,,67.83,HHO,-2.17733,0.221079,0.00216499,0.813905 beta-lactamase_F17Q,beta-lactamase_17,TEM-1,beta-lactamase,P62593,,YES,17,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-2.337,-4.109,1.772,,,,,,,2.192,,67.83,HHO,-2.17733,0.221079,0.00216499,0.805374 beta-lactamase_F58H,beta-lactamase_58,TEM-1,beta-lactamase,P62593,,YES,58,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-2.914,-2.092,-0.822,5.55634,0.266,E,B,1.33,-0.07,2.467,,77.62,PHB,-2.059,0.221079,0.00523369,0.785215 beta-lactamase_F58M,beta-lactamase_58,TEM-1,beta-lactamase,P62593,,YES,58,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-2.914,-4.667,1.753,5.55634,0.266,E,B,1.33,-0.07,2.467,,77.62,PHB,-2.059,0.221079,0.00523369,0.759898 beta-lactamase_F58P,beta-lactamase_58,TEM-1,beta-lactamase,P62593,,YES,58,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-2.914,-4.147,1.233,5.55634,0.266,E,B,1.33,-0.07,2.467,,77.62,PHB,-2.059,0.221079,0.00523369,0.465996 beta-lactamase_F58Q,beta-lactamase_58,TEM-1,beta-lactamase,P62593,,YES,58,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-2.914,-2.803,-0.111,5.55634,0.266,E,B,1.33,-0.07,2.467,,77.62,PHB,-2.059,0.221079,0.00523369,0.788784 beta-lactamase_F64N,beta-lactamase_64,TEM-1,beta-lactamase,P62593,,YES,64,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-0.841,-4.123,3.282,5.70769,0.006,E,B,1.33,-0.95,,,,BHO,-0.892667,0.221079,0.000947691,0.209374 beta-lactamase_F64P,beta-lactamase_64,TEM-1,beta-lactamase,P62593,,YES,64,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-0.841,-4.33,3.489,5.70769,0.006,E,B,1.33,-0.95,,,,BHO,-0.892667,0.221079,0.000947691,0.164418 beta-lactamase_F6M,beta-lactamase_6,TEM-1,beta-lactamase,P62593,,YES,6,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.847,-4.144,2.297,,,,,,,1.276,,67.83,BHB,-2.076,0.221079,0.00261627,0.817081 beta-lactamase_G114F,beta-lactamase_114,TEM-1,beta-lactamase,P62593,,YES,114,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.094,-4.331,3.237,4.92659,0.011,,p,0.77,0.35,2.148,,41.61,AOH,-1.43733,0.221079,0.00224919,0.635242 beta-lactamase_G114M,beta-lactamase_114,TEM-1,beta-lactamase,P62593,,YES,114,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.094,-4.83,3.736,4.92659,0.011,,p,0.77,0.35,2.148,,41.61,AOH,-1.43733,0.221079,0.00224919,0.645101 beta-lactamase_G141N,beta-lactamase_141,TEM-1,beta-lactamase,P62593,,YES,141,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.828,-3.472,2.644,5.03155,0.575,T,l,0.76,-0.28,0.198,,64.69,HOO,-1.08933,0.221079,0.0012419,0.688799 beta-lactamase_G141P,beta-lactamase_141,TEM-1,beta-lactamase,P62593,,YES,141,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.828,-3.881,3.053,5.03155,0.575,T,l,0.76,-0.28,0.198,,64.69,HOO,-1.08933,0.221079,0.0012419,0.502319 beta-lactamase_G194H,beta-lactamase_194,TEM-1,beta-lactamase,P62593,,YES,194,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.396,-4.628,3.232,5.46622,0.276,S,b,0.77,0.36,3.593,,67.83,POA,-1.832,0.221079,0.00392163,0.786138 beta-lactamase_G216F,beta-lactamase_216,TEM-1,beta-lactamase,P62593,,YES,216,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.477,-4.417,2.94,4.91694,0.437,I,A,0.23,-0.58,1.718,,74.48,HOO,-1.68067,0.221079,0.00639568,0.842282 beta-lactamase_G216K,beta-lactamase_216,TEM-1,beta-lactamase,P62593,,YES,216,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.477,-2.765,1.288,4.91694,0.437,I,A,0.23,-0.58,1.718,,74.48,HOO,-1.68067,0.221079,0.00639568,0.82866 beta-lactamase_G216N,beta-lactamase_216,TEM-1,beta-lactamase,P62593,,YES,216,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.477,-2.771,1.294,4.91694,0.437,I,A,0.23,-0.58,1.718,,74.48,HOO,-1.68067,0.221079,0.00639568,0.82835 beta-lactamase_G234H,beta-lactamase_234,TEM-1,beta-lactamase,P62593,,YES,234,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.62,-4.68,4.06,4.24221,0.023,E,B,0.46,-0.86,,,,POH,-1.25733,0.221079,0.000889577,0.370045 beta-lactamase_G239G,beta-lactamase_239,TEM-1,beta-lactamase,P62593,,YES,239,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.819,-0.819,,4.85529,0.115,T,l,0.77,-0.62,1.817,,42.31,BOP,-1.45267,0.221079,0.00213852,0.665648 beta-lactamase_G242G,beta-lactamase_242,TEM-1,beta-lactamase,P62593,,YES,242,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.319,-1.319,,4.68003,,E,B,0.87,-1.05,1.079,,50,BOH,-1.428,0.221079,0.00452879,0.548479 beta-lactamase_G248G,beta-lactamase_248,TEM-1,beta-lactamase,P62593,,YES,248,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.794,-1.794,,4.69798,,E,b,0.23,-0.43,1.782,,61.19,HOO,-1.52867,0.221079,0.00428493,0.643796 beta-lactamase_G248I,beta-lactamase_248,TEM-1,beta-lactamase,P62593,,YES,248,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.794,-3.97,2.176,4.69798,,E,b,0.23,-0.43,1.782,,61.19,HOO,-1.52867,0.221079,0.00428493,0.474355 beta-lactamase_G251G,beta-lactamase_251,TEM-1,beta-lactamase,P62593,,YES,251,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.907,-1.907,,5.33865,0.506,T,l,0.73,0.17,10.663,,65.38,AOB,-2.06067,0.221079,0.00733416,0.830177 beta-lactamase_G263C,beta-lactamase_263,TEM-1,beta-lactamase,P62593,,YES,263,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-2.031,-5.248,3.217,5.09799,0.517,S,l,0.77,0.31,16.425,16.425,77.62,POP,-1.78267,0.221079,0.0110582,0.824059 beta-lactamase_G263G,beta-lactamase_263,TEM-1,beta-lactamase,P62593,,YES,263,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-2.031,-2.031,,5.09799,0.517,S,l,0.77,0.31,16.425,16.425,77.62,POP,-1.78267,0.221079,0.0110582,0.805318 beta-lactamase_G263N,beta-lactamase_263,TEM-1,beta-lactamase,P62593,,YES,263,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-2.031,-2.679,0.648,5.09799,0.517,S,l,0.77,0.31,16.425,16.425,77.62,POP,-1.78267,0.221079,0.0110582,0.85811 beta-lactamase_G263Y,beta-lactamase_263,TEM-1,beta-lactamase,P62593,,YES,263,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-2.031,-4.387,2.356,5.09799,0.517,S,l,0.77,0.31,16.425,16.425,77.62,POP,-1.78267,0.221079,0.0110582,0.807511 beta-lactamase_G279G,beta-lactamase_279,TEM-1,beta-lactamase,P62593,,YES,279,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.038,-1.038,,4.53882,,H,A,0.46,-0.97,3.066,,62.59,HOH,-1.36467,0.221079,0.0192826,0.712762 beta-lactamase_G279H,beta-lactamase_279,TEM-1,beta-lactamase,P62593,,YES,279,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.038,-4.708,3.67,4.53882,,H,A,0.46,-0.97,3.066,,62.59,HOH,-1.36467,0.221079,0.0192826,0.531193 beta-lactamase_G279P,beta-lactamase_279,TEM-1,beta-lactamase,P62593,,YES,279,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.038,-3.854,2.816,4.53882,,H,A,0.46,-0.97,3.066,,62.59,HOH,-1.36467,0.221079,0.0192826,0.470795 beta-lactamase_G39F,beta-lactamase_39,TEM-1,beta-lactamase,P62593,,YES,39,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.864,-4.451,2.587,5.35574,0.701,T,L,0.23,0.47,29.926,29.926,77.62,HOH,-1.53633,0.221079,0.00487611,0.895895 beta-lactamase_G39H,beta-lactamase_39,TEM-1,beta-lactamase,P62593,,YES,39,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.864,-3.359,1.495,5.35574,0.701,T,L,0.23,0.47,29.926,29.926,77.62,HOH,-1.53633,0.221079,0.00487611,0.900421 beta-lactamase_G43H,beta-lactamase_43,TEM-1,beta-lactamase,P62593,,YES,43,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.62,-4.68,4.06,5.28886,,E,B,0.77,-0.78,,,,HOH,-1.577,0.221079,0.00120151,0.277925 beta-lactamase_G43P,beta-lactamase_43,TEM-1,beta-lactamase,P62593,,YES,43,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.62,-3.88,3.26,5.28886,,E,B,0.77,-0.78,,,,HOH,-1.577,0.221079,0.00120151,0.267547 beta-lactamase_G43Q,beta-lactamase_43,TEM-1,beta-lactamase,P62593,,YES,43,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.62,-4.124,3.504,5.28886,,E,B,0.77,-0.78,,,,HOH,-1.577,0.221079,0.00120151,0.290522 beta-lactamase_H110M,beta-lactamase_110,TEM-1,beta-lactamase,P62593,,YES,110,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-1.706,-3.324,1.618,5.52635,0.341,G,a,0.35,1.08,31.31,31.31,64.69,BBH,-1.73333,0.221079,0.00441499,0.832674 beta-lactamase_H151M,beta-lactamase_151,TEM-1,beta-lactamase,P62593,,YES,151,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-2.96,-4.581,1.621,5.47408,0.594,H,A,0.35,0.1,1.843,,77.62,HBP,-2.34767,0.221079,0.00216946,0.855183 beta-lactamase_H24M,beta-lactamase_24,TEM-1,beta-lactamase,P62593,,YES,24,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-2.481,-3.144,0.663,5.82767,,,,,,2.708,,93.01,HBO,-1.85167,0.221079,0.00238894,0.849901 beta-lactamase_H285H,beta-lactamase_285,TEM-1,beta-lactamase,P62593,,YES,285,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-1.845,-1.845,,5.64289,0.312,T,a,0.35,0.64,1.401,,72.73,BBH,-1.64567,0.221079,0.101555,0.838281 beta-lactamase_H285W,beta-lactamase_285,TEM-1,beta-lactamase,P62593,,YES,285,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-1.845,-5.065,3.22,5.64289,0.312,T,a,0.35,0.64,1.401,,72.73,BBH,-1.64567,0.221079,0.101555,0.859172 beta-lactamase_I243I,beta-lactamase_243,TEM-1,beta-lactamase,P62593,,YES,243,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.532,-1.532,,5.26886,,E,B,1.68,-1.24,2.289,,50,OHH,-1.46867,0.221079,0.00464034,0.458645 beta-lactamase_I256I,beta-lactamase_256,TEM-1,beta-lactamase,P62593,,YES,256,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.621,-1.621,,5.3196,,E,B,1,-0.84,1.615,,73.08,BHH,-1.80667,0.221079,0.00710634,0.59607 beta-lactamase_I259I,beta-lactamase_259,TEM-1,beta-lactamase,P62593,,YES,259,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.522,-1.522,,5.28457,,E,B,1,-0.8,1.24,,64.34,HHH,-1.53267,0.221079,0.0070773,0.581617 beta-lactamase_I275I,beta-lactamase_275,TEM-1,beta-lactamase,P62593,,YES,275,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.397,-1.397,,5.3999,0.015,H,A,1,-0.52,0.836,,62.59,PHH,-1.541,0.221079,0.0141984,0.602109 beta-lactamase_I278I,beta-lactamase_278,TEM-1,beta-lactamase,P62593,,YES,278,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.348,-1.348,,5.35127,0.015,H,A,0.77,-0.85,2.718,,63.29,AHO,-1.41833,0.221079,0.0310297,0.659327 beta-lactamase_I283I,beta-lactamase_283,TEM-1,beta-lactamase,P62593,,YES,283,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.638,-1.638,,5.4178,0.165,H,A,1.23,0.04,1.576,,69.23,HHB,-1.735,0.221079,0.0429138,0.691719 beta-lactamase_I54Q,beta-lactamase_54,TEM-1,beta-lactamase,P62593,,YES,54,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-2.838,-2.926,0.088,5.40541,0.669,E,B,0.77,-0.14,3.946,,73.78,BHH,-2.337,0.221079,0.00403589,0.814837 beta-lactamase_K109F,beta-lactamase_109,TEM-1,beta-lactamase,P62593,,YES,109,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.734,-4.437,2.703,6.05842,0.787,G,A,1.82,2.21,21.623,21.623,72.73,ABB,-1.63333,0.221079,0.00462493,0.899553 beta-lactamase_K109H,beta-lactamase_109,TEM-1,beta-lactamase,P62593,,YES,109,K,H,KH,PositiveCharge,PositiveCharge,9.74,7.59,-2.15,32,146,155,9,168.6,153.2,-15.4,-1.734,-3.369,1.635,6.05842,0.787,G,A,1.82,2.21,21.623,21.623,72.73,ABB,-1.63333,0.221079,0.00462493,0.903751 beta-lactamase_K190M,beta-lactamase_190,TEM-1,beta-lactamase,P62593,,YES,190,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-1.994,-4.714,2.72,5.49163,0.371,H,A,1.82,0.16,29.753,29.753,77.62,BBH,-1.64167,0.221079,0.00574527,0.906459 beta-lactamase_K252K,beta-lactamase_252,TEM-1,beta-lactamase,P62593,,YES,252,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.94,-1.94,,5.56823,0.766,,B,1.82,1.16,21.796,21.796,67.83,OBO,-2.03333,0.221079,0.00575769,0.877132 beta-lactamase_K284F,beta-lactamase_284,TEM-1,beta-lactamase,P62593,,YES,284,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.981,-4.348,2.367,6.30084,0.848,H,A,1.82,0.67,1.931,,77.62,HBB,-1.82133,0.221079,0.0686156,0.880315 beta-lactamase_K284K,beta-lactamase_284,TEM-1,beta-lactamase,P62593,,YES,284,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.981,-1.981,,6.30084,0.848,H,A,1.82,0.67,1.931,,77.62,HBB,-1.82133,0.221079,0.0686156,0.865725 beta-lactamase_K32W,beta-lactamase_32,TEM-1,beta-lactamase,P62593,,YES,32,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.984,-5.48,3.496,5.55842,0.563,H,A,1.82,0.34,1.754,,73.08,HBA,-2.04233,0.221079,0.00401283,0.866159 beta-lactamase_K71A,beta-lactamase_71,TEM-1,beta-lactamase,P62593,,YES,71,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-0.8,-3.078,2.278,5.15697,,H,A,1.3,-0.99,,,,HBH,-1.209,0.221079,0.00103192,0.150147 beta-lactamase_K71C,beta-lactamase_71,TEM-1,beta-lactamase,P62593,,YES,71,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-0.8,-5.087,4.287,5.15697,,H,A,1.3,-0.99,,,,HBH,-1.209,0.221079,0.00103192,0.265615 beta-lactamase_K71D,beta-lactamase_71,TEM-1,beta-lactamase,P62593,,YES,71,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-0.8,-3.469,2.669,5.15697,,H,A,1.3,-0.99,,,,HBH,-1.209,0.221079,0.00103192,0.132957 beta-lactamase_K71F,beta-lactamase_71,TEM-1,beta-lactamase,P62593,,YES,71,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-0.8,-4.292,3.492,5.15697,,H,A,1.3,-0.99,,,,HBH,-1.209,0.221079,0.00103192,0.151934 beta-lactamase_K71G,beta-lactamase_71,TEM-1,beta-lactamase,P62593,,YES,71,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-0.8,-3.358,2.558,5.15697,,H,A,1.3,-0.99,,,,HBH,-1.209,0.221079,0.00103192,0.138473 beta-lactamase_K71L,beta-lactamase_71,TEM-1,beta-lactamase,P62593,,YES,71,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-0.8,-3.358,2.558,5.15697,,H,A,1.3,-0.99,,,,HBH,-1.209,0.221079,0.00103192,0.137549 beta-lactamase_K71M,beta-lactamase_71,TEM-1,beta-lactamase,P62593,,YES,71,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-0.8,-4.48,3.68,5.15697,,H,A,1.3,-0.99,,,,HBH,-1.209,0.221079,0.00103192,0.168471 beta-lactamase_K71Q,beta-lactamase_71,TEM-1,beta-lactamase,P62593,,YES,71,K,Q,KQ,PositiveCharge,Polar,9.74,6.24429,-3.49571,53,146,146,0,168.6,143.8,-24.8,-0.8,-3.449,2.649,5.15697,,H,A,1.3,-0.99,,,,HBH,-1.209,0.221079,0.00103192,0.199489 beta-lactamase_K71V,beta-lactamase_71,TEM-1,beta-lactamase,P62593,,YES,71,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-0.8,-3.529,2.729,5.15697,,H,A,1.3,-0.99,,,,HBH,-1.209,0.221079,0.00103192,0.142982 beta-lactamase_K71W,beta-lactamase_71,TEM-1,beta-lactamase,P62593,,YES,71,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-0.8,-5.322,4.522,5.15697,,H,A,1.3,-0.99,,,,HBH,-1.209,0.221079,0.00103192,0.149417 beta-lactamase_L100I,beta-lactamase_100,TEM-1,beta-lactamase,P62593,,YES,100,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.218,-1.863,0.645,5.60291,0.343,,B,1.3,0.13,1.173,,63.29,AHH,-1.23467,0.221079,0.00413885,0.713395 beta-lactamase_L100M,beta-lactamase_100,TEM-1,beta-lactamase,P62593,,YES,100,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.218,-4.039,2.821,5.60291,0.343,,B,1.3,0.13,1.173,,63.29,AHH,-1.23467,0.221079,0.00413885,0.633221 beta-lactamase_L100P,beta-lactamase_100,TEM-1,beta-lactamase,P62593,,YES,100,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.218,-4.169,2.951,5.60291,0.343,,B,1.3,0.13,1.173,,63.29,AHH,-1.23467,0.221079,0.00413885,0.41792 beta-lactamase_L100Y,beta-lactamase_100,TEM-1,beta-lactamase,P62593,,YES,100,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.218,-2.879,1.661,5.60291,0.343,,B,1.3,0.13,1.173,,63.29,AHH,-1.23467,0.221079,0.00413885,0.711653 beta-lactamase_L111A,beta-lactamase_111,TEM-1,beta-lactamase,P62593,,YES,111,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.76,-2.229,0.469,5.8705,0.328,T,A,0.84,0.93,3.836,,64.34,BHP,-1.884,0.221079,0.00480671,0.896948 beta-lactamase_L120P,beta-lactamase_120,TEM-1,beta-lactamase,P62593,,YES,120,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.044,-4.17,3.126,5.11974,,H,A,1.3,-1.13,1.988,,64.69,AHO,-1.13633,0.221079,0.00143563,0.333262 beta-lactamase_L192P,beta-lactamase_192,TEM-1,beta-lactamase,P62593,,YES,192,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.254,-4.129,2.875,5.68899,0.095,H,A,1.3,0.35,1.756,,60.14,HHP,-1.41833,0.221079,0.00558728,0.323153 beta-lactamase_L199D,beta-lactamase_199,TEM-1,beta-lactamase,P62593,,YES,199,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-2.942,-3.009,0.067,5.57712,0.832,H,A,0.82,0.42,15.302,15.302,77.62,PHH,-2.32933,0.221079,0.0048649,0.934853 beta-lactamase_L199M,beta-lactamase_199,TEM-1,beta-lactamase,P62593,,YES,199,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-2.942,-4.728,1.786,5.57712,0.832,H,A,0.82,0.42,15.302,15.302,77.62,PHH,-2.32933,0.221079,0.0048649,0.901132 beta-lactamase_L199W,beta-lactamase_199,TEM-1,beta-lactamase,P62593,,YES,199,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-2.942,-5.582,2.64,5.57712,0.832,H,A,0.82,0.42,15.302,15.302,77.62,PHH,-2.32933,0.221079,0.0048649,0.906078 beta-lactamase_L199Y,beta-lactamase_199,TEM-1,beta-lactamase,P62593,,YES,199,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-2.942,-4.431,1.489,5.57712,0.832,H,A,0.82,0.42,15.302,15.302,77.62,PHH,-2.32933,0.221079,0.0048649,0.906212 beta-lactamase_L19M,beta-lactamase_19,TEM-1,beta-lactamase,P62593,,YES,19,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.682,-2.913,1.231,,,,,,,4.261,,93.01,OHO,-1.894,0.221079,0.00215974,0.847965 beta-lactamase_L205M,beta-lactamase_205,TEM-1,beta-lactamase,P62593,,YES,205,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-0.922,-3.889,2.967,5.67023,,H,A,1.3,-0.46,0.678,,42.31,PHH,-1.57767,0.221079,0.00255802,0.243032 beta-lactamase_L205P,beta-lactamase_205,TEM-1,beta-lactamase,P62593,,YES,205,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-0.922,-4.159,3.237,5.67023,,H,A,1.3,-0.46,0.678,,42.31,PHH,-1.57767,0.221079,0.00255802,0.191826 beta-lactamase_L247L,beta-lactamase_247,TEM-1,beta-lactamase,P62593,,YES,247,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.48,-1.48,,5.28771,0.007,E,B,2.89,-0.72,2.951,,63.99,HHO,-1.79833,0.221079,0.00611275,0.476485 beta-lactamase_L247N,beta-lactamase_247,TEM-1,beta-lactamase,P62593,,YES,247,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.48,-4.159,2.679,5.28771,0.007,E,B,2.89,-0.72,2.951,,63.99,HHO,-1.79833,0.221079,0.00611275,0.233914 beta-lactamase_L282L,beta-lactamase_282,TEM-1,beta-lactamase,P62593,,YES,282,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.586,-1.586,,5.16743,0.007,H,A,1.07,0.34,31.31,31.31,63.99,PHH,-1.82367,0.221079,0.0449821,0.69716 beta-lactamase_L28D,beta-lactamase_28,TEM-1,beta-lactamase,P62593,,YES,28,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.579,-3.96,2.381,5.42969,0.277,H,A,0.07,-0.16,19.748,19.748,93.01,PHH,-2.11333,0.221079,0.00359321,0.792336 beta-lactamase_L28F,beta-lactamase_28,TEM-1,beta-lactamase,P62593,,YES,28,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.579,-3.916,2.337,5.42969,0.277,H,A,0.07,-0.16,19.748,19.748,93.01,PHH,-2.11333,0.221079,0.00359321,0.835017 beta-lactamase_L28W,beta-lactamase_28,TEM-1,beta-lactamase,P62593,,YES,28,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.579,-5.332,3.753,5.42969,0.277,H,A,0.07,-0.16,19.748,19.748,93.01,PHH,-2.11333,0.221079,0.00359321,0.838594 beta-lactamase_L28Y,beta-lactamase_28,TEM-1,beta-lactamase,P62593,,YES,28,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.579,-4.094,2.515,5.42969,0.277,H,A,0.07,-0.16,19.748,19.748,93.01,PHH,-2.11333,0.221079,0.00359321,0.833103 beta-lactamase_L47Y,beta-lactamase_47,TEM-1,beta-lactamase,P62593,,YES,47,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.876,-3.117,1.241,5.27297,0.007,E,B,1.07,0.2,1.244,,67.83,AHA,-1.639,0.221079,0.00439844,0.646571 beta-lactamase_L49W,beta-lactamase_49,TEM-1,beta-lactamase,P62593,,YES,49,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.897,-5.315,3.418,5.86005,0.131,T,A,1.3,0.04,3.112,,64.69,AHP,-1.99233,0.221079,0.00401477,0.709166 beta-lactamase_L74F,beta-lactamase_74,TEM-1,beta-lactamase,P62593,,YES,74,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.296,-3.848,2.552,5.50288,,H,A,1.75,-0.91,1.581,,50,HHO,-1.34933,0.221079,0.00493255,0.273569 beta-lactamase_L74W,beta-lactamase_74,TEM-1,beta-lactamase,P62593,,YES,74,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.296,-5.261,3.965,5.50288,,H,A,1.75,-0.91,1.581,,50,HHO,-1.34933,0.221079,0.00493255,0.269071 beta-lactamase_L74Y,beta-lactamase_74,TEM-1,beta-lactamase,P62593,,YES,74,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.296,-4.105,2.809,5.50288,,H,A,1.75,-0.91,1.581,,50,HHO,-1.34933,0.221079,0.00493255,0.269858 beta-lactamase_M115M,beta-lactamase_115,TEM-1,beta-lactamase,P62593,,YES,115,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.389,-1.389,,4.89743,0.019,E,B,1.3,0.08,1.236,,69.58,OHP,-1.25433,0.221079,0.0034337,0.607817 beta-lactamase_M127M,beta-lactamase_127,TEM-1,beta-lactamase,P62593,,YES,127,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-2.251,-2.251,,5.40552,0.312,S,A,1.07,0.32,1.671,,72.73,PHP,-1.40433,0.221079,0.00437927,0.82468 beta-lactamase_M153F,beta-lactamase_153,TEM-1,beta-lactamase,P62593,,YES,153,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-3.193,-3.944,0.751,5.46509,0.14,T,A,1.07,-0.11,2.061,,77.62,PHO,-2.25767,0.221079,0.00509109,0.7757 beta-lactamase_M153M,beta-lactamase_153,TEM-1,beta-lactamase,P62593,,YES,153,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-3.193,-3.193,,5.46509,0.14,T,A,1.07,-0.11,2.061,,77.62,PHO,-2.25767,0.221079,0.00509109,0.792124 beta-lactamase_M180M,beta-lactamase_180,TEM-1,beta-lactamase,P62593,,YES,180,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-2.795,-2.795,,4.96809,0.242,,B,1.07,-0.94,31.829,31.829,77.62,PHO,-1.56433,0.221079,0.00552048,0.848555 beta-lactamase_M184M,beta-lactamase_184,TEM-1,beta-lactamase,P62593,,YES,184,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.593,-1.593,,5.39575,,H,A,1.3,-0.87,2.893,,62.94,HHH,-1.41,0.221079,0.00356019,0.504783 beta-lactamase_M1M,beta-lactamase_1,TEM-1,beta-lactamase,P62593,,YES,1,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.998,-1.998,,,,,,,,,,,OHP,-1.97,0.221079,0.00162771,0.533454 beta-lactamase_M209D,beta-lactamase_209,TEM-1,beta-lactamase,P62593,,YES,209,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.442,-4.067,2.625,5.44502,,H,A,1.75,-0.97,1.402,,64.69,HHA,-1.52633,0.221079,0.00625021,0.208829 beta-lactamase_M209H,beta-lactamase_209,TEM-1,beta-lactamase,P62593,,YES,209,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.442,-4.813,3.371,5.44502,,H,A,1.75,-0.97,1.402,,64.69,HHA,-1.52633,0.221079,0.00625021,0.240728 beta-lactamase_M209M,beta-lactamase_209,TEM-1,beta-lactamase,P62593,,YES,209,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.442,-1.442,,5.44502,,H,A,1.75,-0.97,1.402,,64.69,HHA,-1.52633,0.221079,0.00625021,0.472077 beta-lactamase_M209P,beta-lactamase_209,TEM-1,beta-lactamase,P62593,,YES,209,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.442,-4.077,2.635,5.44502,,H,A,1.75,-0.97,1.402,,64.69,HHA,-1.52633,0.221079,0.00625021,0.218203 beta-lactamase_M268M,beta-lactamase_268,TEM-1,beta-lactamase,P62593,,YES,268,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-2.023,-2.023,,5.4797,0.471,H,A,0.09,0.3,1.071,,65.73,PHA,-2.16233,0.221079,0.0102525,0.826078 beta-lactamase_M66M,beta-lactamase_66,TEM-1,beta-lactamase,P62593,,YES,66,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.362,-1.362,,5.29561,0.013,,A,1.3,-0.7,1.319,,73.08,OHH,-1.49567,0.221079,0.00412876,0.557285 beta-lactamase_M67M,beta-lactamase_67,TEM-1,beta-lactamase,P62593,,YES,67,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-2.231,-2.231,,4.9618,0.006,G,P,1.07,-0.81,1.463,,65.03,HHP,-1.502,0.221079,0.00409753,0.657062 beta-lactamase_N152M,beta-lactamase_152,TEM-1,beta-lactamase,P62593,,YES,152,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-2.757,-4.737,1.98,5.98571,0.863,H,A,0.09,0.92,2.061,,77.62,BPH,-2.97,0.221079,0.00471429,0.890154 beta-lactamase_N152W,beta-lactamase_152,TEM-1,beta-lactamase,P62593,,YES,152,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-2.757,-5.472,2.715,5.98571,0.863,H,A,0.09,0.92,2.061,,77.62,BPH,-2.97,0.221079,0.00471429,0.903163 beta-lactamase_N272N,beta-lactamase_272,TEM-1,beta-lactamase,P62593,,YES,272,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-1.127,-1.127,,5.37826,0.081,H,A,0.09,-0.97,1.468,,63.64,BPB,-1.56333,0.221079,0.00545371,0.714709 beta-lactamase_N50Q,beta-lactamase_50,TEM-1,beta-lactamase,P62593,,YES,50,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-2.979,-2.653,-0.326,5.51261,0.912,T,A,1.07,1.24,1.581,,77.62,HPP,-2.134,0.221079,0.0047211,0.898895 beta-lactamase_N98N,beta-lactamase_98,TEM-1,beta-lactamase,P62593,,YES,98,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-2.973,-2.973,,6.59973,0.963,G,A,1.07,1.35,1.332,,77.62,PPA,-2.07867,0.221079,0.00505389,0.873469 beta-lactamase_N98W,beta-lactamase_98,TEM-1,beta-lactamase,P62593,,YES,98,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-2.973,-5.455,2.482,6.59973,0.963,G,A,1.07,1.35,1.332,,77.62,PPA,-2.07867,0.221079,0.00505389,0.897779 beta-lactamase_P249P,beta-lactamase_249,TEM-1,beta-lactamase,P62593,,YES,249,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.312,-1.312,,5.10655,0.256,S,B,0.99,0.04,0.479,,72.73,OOA,-1.81367,0.221079,0.00220169,0.445858 beta-lactamase_P253M,beta-lactamase_253,TEM-1,beta-lactamase,P62593,,YES,253,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-2.253,-4.761,2.508,5.24842,0.308,,B,0.73,-0.46,2.293,,73.08,BOP,-2.10633,0.221079,0.00786358,0.830574 beta-lactamase_P253P,beta-lactamase_253,TEM-1,beta-lactamase,P62593,,YES,253,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-2.253,-2.253,,5.24842,0.308,,B,0.73,-0.46,2.293,,73.08,BOP,-2.10633,0.221079,0.00786358,0.649183 beta-lactamase_P60W,beta-lactamase_60,TEM-1,beta-lactamase,P62593,,YES,60,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-2.469,-5.456,2.987,5.51353,0.256,T,A,0.73,-0.56,3.653,,77.62,BOA,-1.97633,0.221079,0.00521318,0.86963 beta-lactamase_Q265Q,beta-lactamase_265,TEM-1,beta-lactamase,P62593,,YES,265,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.58,-2.58,,6.62674,1.116,,A,0.03,1.17,12.514,12.514,69.58,PPH,-1.978,0.221079,0.00811926,0.871387 beta-lactamase_Q274C,beta-lactamase_274,TEM-1,beta-lactamase,P62593,,YES,274,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.082,-4.784,2.702,5.6671,0.066,H,A,0.11,-0.27,2.354,,64.69,BPH,-1.931,0.221079,0.0110418,0.822969 beta-lactamase_Q274F,beta-lactamase_274,TEM-1,beta-lactamase,P62593,,YES,274,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.082,-4.101,2.019,5.6671,0.066,H,A,0.11,-0.27,2.354,,64.69,BPH,-1.931,0.221079,0.0110418,0.74865 beta-lactamase_Q274M,beta-lactamase_274,TEM-1,beta-lactamase,P62593,,YES,274,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.082,-4.385,2.303,5.6671,0.066,H,A,0.11,-0.27,2.354,,64.69,BPH,-1.931,0.221079,0.0110418,0.761261 beta-lactamase_Q274N,beta-lactamase_274,TEM-1,beta-lactamase,P62593,,YES,274,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.082,-3.838,1.756,5.6671,0.066,H,A,0.11,-0.27,2.354,,64.69,BPH,-1.931,0.221079,0.0110418,0.77822 beta-lactamase_Q274Q,beta-lactamase_274,TEM-1,beta-lactamase,P62593,,YES,274,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.082,-2.082,,5.6671,0.066,H,A,0.11,-0.27,2.354,,64.69,BPH,-1.931,0.221079,0.0110418,0.805026 beta-lactamase_Q274V,beta-lactamase_274,TEM-1,beta-lactamase,P62593,,YES,274,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.082,-2.238,0.156,5.6671,0.066,H,A,0.11,-0.27,2.354,,64.69,BPH,-1.931,0.221079,0.0110418,0.802994 beta-lactamase_Q4M,beta-lactamase_4,TEM-1,beta-lactamase,P62593,,YES,4,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,,-4.411,1.847,,,,,,,,,,HPB,,0.221079,0.00316562,0.732256 beta-lactamase_R159F,beta-lactamase_159,TEM-1,beta-lactamase,P62593,,YES,159,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-0.94,-4.255,3.315,5.64971,0.316,,B,0.68,-0.55,1.172,,64.34,PBH,-1.011,0.221079,0.00108472,0.632395 beta-lactamase_R238R,beta-lactamase_238,TEM-1,beta-lactamase,P62593,,YES,238,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.002,-2.002,,5.87663,0.564,T,L,0.45,1.09,4.195,,72.73,ABO,-1.62633,0.221079,0.00743256,0.850894 beta-lactamase_R241R,beta-lactamase_241,TEM-1,beta-lactamase,P62593,,YES,241,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.433,-1.433,,5.02621,0.094,E,B,0.68,-0.16,1.327,,50,PBO,-1.42967,0.221079,0.00452736,0.711092 beta-lactamase_R255R,beta-lactamase_255,TEM-1,beta-lactamase,P62593,,YES,255,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-2.266,-2.266,,5.55882,0.141,E,B,0.68,0.38,1.199,,63.99,PBH,-2.00433,0.221079,0.00499612,0.697145 beta-lactamase_R271K,beta-lactamase_271,TEM-1,beta-lactamase,P62593,,YES,271,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.249,-3.082,1.833,5.24516,0.085,H,A,1.67,-0.05,0.474,,63.99,ABP,-1.36633,0.221079,0.00752082,0.685049 beta-lactamase_R271M,beta-lactamase_271,TEM-1,beta-lactamase,P62593,,YES,271,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.249,-4.399,3.15,5.24516,0.085,H,A,1.67,-0.05,0.474,,63.99,ABP,-1.36633,0.221079,0.00752082,0.737768 beta-lactamase_R271N,beta-lactamase_271,TEM-1,beta-lactamase,P62593,,YES,271,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.249,-3.628,2.379,5.24516,0.085,H,A,1.67,-0.05,0.474,,63.99,ABP,-1.36633,0.221079,0.00752082,0.713644 beta-lactamase_R271R,beta-lactamase_271,TEM-1,beta-lactamase,P62593,,YES,271,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.249,-1.249,,5.24516,0.085,H,A,1.67,-0.05,0.474,,63.99,ABP,-1.36633,0.221079,0.00752082,0.675655 beta-lactamase_R273C,beta-lactamase_273,TEM-1,beta-lactamase,P62593,,YES,273,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-2.314,-5.09,2.776,,0.564,H,A,1.2,1.57,,,73.78,ABP,-1.841,0.221079,0.0077952,0.830751 beta-lactamase_R273F,beta-lactamase_273,TEM-1,beta-lactamase,P62593,,YES,273,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.314,-4.428,2.114,,0.564,H,A,1.2,1.57,,,73.78,ABP,-1.841,0.221079,0.0077952,0.807465 beta-lactamase_R273H,beta-lactamase_273,TEM-1,beta-lactamase,P62593,,YES,273,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-2.314,-4.599,2.285,,0.564,H,A,1.2,1.57,,,73.78,ABP,-1.841,0.221079,0.0077952,0.824305 beta-lactamase_R273M,beta-lactamase_273,TEM-1,beta-lactamase,P62593,,YES,273,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.314,-4.698,2.384,,0.564,H,A,1.2,1.57,,,73.78,ABP,-1.841,0.221079,0.0077952,0.830661 beta-lactamase_R273N,beta-lactamase_273,TEM-1,beta-lactamase,P62593,,YES,273,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.314,-3.744,1.43,,0.564,H,A,1.2,1.57,,,73.78,ABP,-1.841,0.221079,0.0077952,0.840797 beta-lactamase_R273P,beta-lactamase_273,TEM-1,beta-lactamase,P62593,,YES,273,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-2.314,-2.669,0.355,,0.564,H,A,1.2,1.57,,,73.78,ABP,-1.841,0.221079,0.0077952,0.791816 beta-lactamase_R273W,beta-lactamase_273,TEM-1,beta-lactamase,P62593,,YES,273,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.314,-5.456,3.142,,0.564,H,A,1.2,1.57,,,73.78,ABP,-1.841,0.221079,0.0077952,0.789139 beta-lactamase_S104M,beta-lactamase_104,TEM-1,beta-lactamase,P62593,,YES,104,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.015,-4.54,3.525,4.92365,0.04,,b,0.82,0.57,4.02,,63.29,HPO,-1.05267,0.221079,0.00218083,0.536139 beta-lactamase_S122P,beta-lactamase_122,TEM-1,beta-lactamase,P62593,,YES,122,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.406,-4.011,1.605,4.87767,0.352,H,A,0.73,-0.54,1.581,,77.62,OPH,-1.39767,0.221079,0.00497825,0.523272 beta-lactamase_S128E,beta-lactamase_128,TEM-1,beta-lactamase,P62593,,YES,128,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-0.84,-3.215,2.375,5.37153,0.08,,L,0.73,-0.32,,,,HPA,-1.30233,0.221079,0.00071483,0.228391 beta-lactamase_S128F,beta-lactamase_128,TEM-1,beta-lactamase,P62593,,YES,128,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-0.84,-4.067,3.227,5.37153,0.08,,L,0.73,-0.32,,,,HPA,-1.30233,0.221079,0.00071483,0.220797 beta-lactamase_S128M,beta-lactamase_128,TEM-1,beta-lactamase,P62593,,YES,128,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-0.84,-4.48,3.64,5.37153,0.08,,L,0.73,-0.32,,,,HPA,-1.30233,0.221079,0.00071483,0.241776 beta-lactamase_S128P,beta-lactamase_128,TEM-1,beta-lactamase,P62593,,YES,128,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-0.84,-3.655,2.815,5.37153,0.08,,L,0.73,-0.32,,,,HPA,-1.30233,0.221079,0.00071483,0.237391 beta-lactamase_S201M,beta-lactamase_201,TEM-1,beta-lactamase,P62593,,YES,201,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.183,-4.493,3.31,4.85496,0.064,H,A,0.77,-0.07,4.045,,64.69,HPB,-1.451,0.221079,0.00198815,0.718597 beta-lactamase_S233M,beta-lactamase_233,TEM-1,beta-lactamase,P62593,,YES,233,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.886,-4.626,2.74,4.98121,0.016,E,B,0.48,-1.01,5.361,,77.62,BPO,-1.17267,0.221079,0.00311415,0.501775 beta-lactamase_S240S,beta-lactamase_240,TEM-1,beta-lactamase,P62593,,YES,240,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.537,-1.537,,4.75024,,,B,0.74,-0.74,0.357,,65.38,OPB,-1.263,0.221079,0.00591201,0.673947 beta-lactamase_S254S,beta-lactamase_254,TEM-1,beta-lactamase,P62593,,YES,254,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.126,-2.126,,5.49575,0.312,,a,0.25,-0.48,24.91,24.91,69.58,OPB,-2.215,0.221079,0.00369,0.842292 beta-lactamase_S264H,beta-lactamase_264,TEM-1,beta-lactamase,P62593,,YES,264,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.985,-4.721,2.736,4.67475,0.04,,B,0.25,0.29,34.251,34.251,73.78,OPP,-2.19867,0.221079,0.0119399,0.689091 beta-lactamase_S264S,beta-lactamase_264,TEM-1,beta-lactamase,P62593,,YES,264,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.985,-1.985,,4.67475,0.04,,B,0.25,0.29,34.251,34.251,73.78,OPP,-2.19867,0.221079,0.0119399,0.766391 beta-lactamase_S281S,beta-lactamase_281,TEM-1,beta-lactamase,P62593,,YES,281,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.247,-2.247,,4.73591,0.128,H,A,0.25,-0.26,2.144,,77.62,HPH,-1.847,0.221079,0.0406482,0.824907 beta-lactamase_S51F,beta-lactamase_51,TEM-1,beta-lactamase,P62593,,YES,51,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.526,-4.284,2.758,5.06164,0.496,T,A,0.25,0.26,1.699,,72.73,PPO,-1.88467,0.221079,0.00504821,0.830205 beta-lactamase_S51H,beta-lactamase_51,TEM-1,beta-lactamase,P62593,,YES,51,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.526,-4.622,3.096,5.06164,0.496,T,A,0.25,0.26,1.699,,72.73,PPO,-1.88467,0.221079,0.00504821,0.837732 beta-lactamase_S51M,beta-lactamase_51,TEM-1,beta-lactamase,P62593,,YES,51,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.526,-4.705,3.179,5.06164,0.496,T,A,0.25,0.26,1.699,,72.73,PPO,-1.88467,0.221079,0.00504821,0.840047 beta-lactamase_S51W,beta-lactamase_51,TEM-1,beta-lactamase,P62593,,YES,51,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.526,-5.435,3.909,5.06164,0.496,T,A,0.25,0.26,1.699,,72.73,PPO,-1.88467,0.221079,0.00504821,0.814126 beta-lactamase_T112F,beta-lactamase_112,TEM-1,beta-lactamase,P62593,,YES,112,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.186,-4.382,2.196,6.47162,0.921,T,A,0.77,1.06,2.04,,73.78,HPA,-1.925,0.221079,0.00531334,0.89878 beta-lactamase_T116D,beta-lactamase_116,TEM-1,beta-lactamase,P62593,,YES,116,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.28,-3.524,2.244,4.78335,0.115,E,B,0.69,-0.12,0.343,,67.48,HPH,-1.39967,0.221079,0.00336175,0.641454 beta-lactamase_T116H,beta-lactamase_116,TEM-1,beta-lactamase,P62593,,YES,116,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.28,-4.615,3.335,4.78335,0.115,E,B,0.69,-0.12,0.343,,67.48,HPH,-1.39967,0.221079,0.00336175,0.723361 beta-lactamase_T116N,beta-lactamase_116,TEM-1,beta-lactamase,P62593,,YES,116,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.28,-2.515,1.235,4.78335,0.115,E,B,0.69,-0.12,0.343,,67.48,HPH,-1.39967,0.221079,0.00336175,0.750971 beta-lactamase_T116P,beta-lactamase_116,TEM-1,beta-lactamase,P62593,,YES,116,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.28,-3.831,2.551,4.78335,0.115,E,B,0.69,-0.12,0.343,,67.48,HPH,-1.39967,0.221079,0.00336175,0.518385 beta-lactamase_T116Q,beta-lactamase_116,TEM-1,beta-lactamase,P62593,,YES,116,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.28,-3.898,2.618,4.78335,0.115,E,B,0.69,-0.12,0.343,,67.48,HPH,-1.39967,0.221079,0.00336175,0.696606 beta-lactamase_T158W,beta-lactamase_158,TEM-1,beta-lactamase,P62593,,YES,158,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.116,-5.268,4.152,5.32011,0.036,,B,0.98,-0.85,2.755,,69.58,HPB,-1.269,0.221079,0.00341825,0.358647 beta-lactamase_T193C,beta-lactamase_193,TEM-1,beta-lactamase,P62593,,YES,193,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.914,-4.857,2.943,5.67952,0.439,H,a,0.3,0.33,1.863,,63.99,HPO,-1.52133,0.221079,0.00482669,0.884911 beta-lactamase_T193Q,beta-lactamase_193,TEM-1,beta-lactamase,P62593,,YES,193,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.914,-4.169,2.255,5.67952,0.439,H,a,0.3,0.33,1.863,,63.99,HPO,-1.52133,0.221079,0.00482669,0.870601 beta-lactamase_T261C,beta-lactamase_261,TEM-1,beta-lactamase,P62593,,YES,261,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.88,-3.339,0.459,5.65483,0.014,E,B,0.53,-0.39,2.449,,77.62,HPP,-1.771,0.221079,0.0123091,0.688001 beta-lactamase_T261F,beta-lactamase_261,TEM-1,beta-lactamase,P62593,,YES,261,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.88,-3.862,0.982,5.65483,0.014,E,B,0.53,-0.39,2.449,,77.62,HPP,-1.771,0.221079,0.0123091,0.572983 beta-lactamase_T261P,beta-lactamase_261,TEM-1,beta-lactamase,P62593,,YES,261,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.88,-4.165,1.285,5.65483,0.014,E,B,0.53,-0.39,2.449,,77.62,HPP,-1.771,0.221079,0.0123091,0.543388 beta-lactamase_T261T,beta-lactamase_261,TEM-1,beta-lactamase,P62593,,YES,261,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.88,-2.88,,5.65483,0.014,E,B,0.53,-0.39,2.449,,77.62,HPP,-1.771,0.221079,0.0123091,0.718125 beta-lactamase_T262T,beta-lactamase_262,TEM-1,beta-lactamase,P62593,,YES,262,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.332,-1.332,,5.06002,0.108,E,B,0.3,-0.55,1.423,,67.83,PPO,-2.081,0.221079,0.00853516,0.770577 beta-lactamase_T267T,beta-lactamase_267,TEM-1,beta-lactamase,P62593,,YES,267,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-2.308,-2.308,,5.28263,0.54,,B,0.69,-0.14,0.374,,73.78,HPH,-1.9,0.221079,0.0102128,0.76769 beta-lactamase_V101H,beta-lactamase_101,TEM-1,beta-lactamase,P62593,,YES,101,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.295,-4.92,3.625,5.49045,0.342,,B,0.96,0,1.675,,73.08,HHA,-1.54367,0.221079,0.00374492,0.723378 beta-lactamase_V101K,beta-lactamase_101,TEM-1,beta-lactamase,P62593,,YES,101,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.295,-3.742,2.447,5.49045,0.342,,B,0.96,0,1.675,,73.08,HHA,-1.54367,0.221079,0.00374492,0.692834 beta-lactamase_V101M,beta-lactamase_101,TEM-1,beta-lactamase,P62593,,YES,101,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.295,-2.812,1.517,5.49045,0.342,,B,0.96,0,1.675,,73.08,HHA,-1.54367,0.221079,0.00374492,0.740247 beta-lactamase_V101Q,beta-lactamase_101,TEM-1,beta-lactamase,P62593,,YES,101,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.295,-4.106,2.811,5.49045,0.342,,B,0.96,0,1.675,,73.08,HHA,-1.54367,0.221079,0.00374492,0.693762 beta-lactamase_V157C,beta-lactamase_157,TEM-1,beta-lactamase,P62593,,YES,157,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.751,-4.91,3.159,5.51733,0.308,S,a,0.96,-0.75,1.847,,69.58,BHP,-2.00767,0.221079,0.00506849,0.871332 beta-lactamase_V157F,beta-lactamase_157,TEM-1,beta-lactamase,P62593,,YES,157,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.751,-3.968,2.217,5.51733,0.308,S,a,0.96,-0.75,1.847,,69.58,BHP,-2.00767,0.221079,0.00506849,0.850012 beta-lactamase_V157H,beta-lactamase_157,TEM-1,beta-lactamase,P62593,,YES,157,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.751,-3.319,1.568,5.51733,0.308,S,a,0.96,-0.75,1.847,,69.58,BHP,-2.00767,0.221079,0.00506849,0.878091 beta-lactamase_V157M,beta-lactamase_157,TEM-1,beta-lactamase,P62593,,YES,157,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.751,-2.587,0.836,5.51733,0.308,S,a,0.96,-0.75,1.847,,69.58,BHP,-2.00767,0.221079,0.00506849,0.876576 beta-lactamase_V157T,beta-lactamase_157,TEM-1,beta-lactamase,P62593,,YES,157,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.751,-2.302,0.551,5.51733,0.308,S,a,0.96,-0.75,1.847,,69.58,BHP,-2.00767,0.221079,0.00506849,0.877363 beta-lactamase_V157W,beta-lactamase_157,TEM-1,beta-lactamase,P62593,,YES,157,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.751,-5.264,3.513,5.51733,0.308,S,a,0.96,-0.75,1.847,,69.58,BHP,-2.00767,0.221079,0.00506849,0.851576 beta-lactamase_V157Y,beta-lactamase_157,TEM-1,beta-lactamase,P62593,,YES,157,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.751,-2.838,1.087,5.51733,0.308,S,a,0.96,-0.75,1.847,,69.58,BHP,-2.00767,0.221079,0.00506849,0.87355 beta-lactamase_V214M,beta-lactamase_214,TEM-1,beta-lactamase,P62593,,YES,214,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.299,-4.251,2.952,5.74008,0.375,S,A,1.19,-0.44,1.899,,74.48,BHH,-1.53733,0.221079,0.00628442,0.644877 beta-lactamase_V257V,beta-lactamase_257,TEM-1,beta-lactamase,P62593,,YES,257,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.533,-1.533,,5.31999,,E,B,0.96,-0.7,1.463,,58.74,HHH,-1.70967,0.221079,0.00756629,0.591601 beta-lactamase_V258C,beta-lactamase_258,TEM-1,beta-lactamase,P62593,,YES,258,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.975,-3.191,1.216,5.16083,,E,B,1.64,-1.02,2.124,,67.83,HHH,-1.67667,0.221079,0.007931,0.594955 beta-lactamase_V258E,beta-lactamase_258,TEM-1,beta-lactamase,P62593,,YES,258,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.975,-3.685,1.71,5.16083,,E,B,1.64,-1.02,2.124,,67.83,HHH,-1.67667,0.221079,0.007931,0.394369 beta-lactamase_V258H,beta-lactamase_258,TEM-1,beta-lactamase,P62593,,YES,258,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.975,-4.874,2.899,5.16083,,E,B,1.64,-1.02,2.124,,67.83,HHH,-1.67667,0.221079,0.007931,0.286686 beta-lactamase_V258K,beta-lactamase_258,TEM-1,beta-lactamase,P62593,,YES,258,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.975,-3.678,1.703,5.16083,,E,B,1.64,-1.02,2.124,,67.83,HHH,-1.67667,0.221079,0.007931,0.407679 beta-lactamase_V258L,beta-lactamase_258,TEM-1,beta-lactamase,P62593,,YES,258,V,L,VL,Hydrophobic,Hydrophobic,5.60847,9.7088,4.10033,32,117,131,14,140,166.7,26.7,-1.975,-3.065,1.09,5.16083,,E,B,1.64,-1.02,2.124,,67.83,HHH,-1.67667,0.221079,0.007931,0.578028 beta-lactamase_V258M,beta-lactamase_258,TEM-1,beta-lactamase,P62593,,YES,258,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.975,-3.198,1.223,5.16083,,E,B,1.64,-1.02,2.124,,67.83,HHH,-1.67667,0.221079,0.007931,0.571014 beta-lactamase_V258P,beta-lactamase_258,TEM-1,beta-lactamase,P62593,,YES,258,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.975,-3.927,1.952,5.16083,,E,B,1.64,-1.02,2.124,,67.83,HHH,-1.67667,0.221079,0.007931,0.437275 beta-lactamase_V258Q,beta-lactamase_258,TEM-1,beta-lactamase,P62593,,YES,258,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.975,-4.103,2.128,5.16083,,E,B,1.64,-1.02,2.124,,67.83,HHH,-1.67667,0.221079,0.007931,0.366619 beta-lactamase_V258V,beta-lactamase_258,TEM-1,beta-lactamase,P62593,,YES,258,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.975,-1.975,,5.16083,,E,B,1.64,-1.02,2.124,,67.83,HHH,-1.67667,0.221079,0.007931,0.468875 beta-lactamase_V258W,beta-lactamase_258,TEM-1,beta-lactamase,P62593,,YES,258,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.975,-5.384,3.409,5.16083,,E,B,1.64,-1.02,2.124,,67.83,HHH,-1.67667,0.221079,0.007931,0.289317 beta-lactamase_V29F,beta-lactamase_29,TEM-1,beta-lactamase,P62593,,YES,29,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-2.856,-4.364,1.508,5.58481,0.733,H,A,0.23,-0.78,1.287,,93.01,HHB,-2.24733,0.221079,0.00318969,0.865519 beta-lactamase_V29H,beta-lactamase_29,TEM-1,beta-lactamase,P62593,,YES,29,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-2.856,-4.571,1.715,5.58481,0.733,H,A,0.23,-0.78,1.287,,93.01,HHB,-2.24733,0.221079,0.00318969,0.8663 beta-lactamase_V29K,beta-lactamase_29,TEM-1,beta-lactamase,P62593,,YES,29,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-2.856,-2.195,-0.661,5.58481,0.733,H,A,0.23,-0.78,1.287,,93.01,HHB,-2.24733,0.221079,0.00318969,0.880718 beta-lactamase_V72H,beta-lactamase_72,TEM-1,beta-lactamase,P62593,,YES,72,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.658,-4.908,3.25,5.80324,,H,A,2.78,-1.03,2.964,,65.73,BHH,-1.32167,0.221079,0.00501194,0.300269 beta-lactamase_V72M,beta-lactamase_72,TEM-1,beta-lactamase,P62593,,YES,72,V,M,VM,Hydrophobic,Hydrophobic,5.60847,5.74,0.131535,21,117,149,32,140,162.9,22.9,-1.658,-4.404,2.746,5.80324,,H,A,2.78,-1.03,2.964,,65.73,BHH,-1.32167,0.221079,0.00501194,0.319598 beta-lactamase_V72W,beta-lactamase_72,TEM-1,beta-lactamase,P62593,,YES,72,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.658,-3.279,1.621,5.80324,,H,A,2.78,-1.03,2.964,,65.73,BHH,-1.32167,0.221079,0.00501194,0.525395 beta-lactamase_W163W,beta-lactamase_163,TEM-1,beta-lactamase,P62593,,YES,163,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-1.843,-1.843,,6.2765,0.467,,B,1.22,-0.5,3.642,,63.99,BHA,-1.269,0.221079,0.00418955,0.853714 beta-lactamase_W208W,beta-lactamase_208,TEM-1,beta-lactamase,P62593,,YES,208,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-0.818,-0.818,,5.26277,0.067,H,A,0.99,-0.65,,,,AHH,-1.44133,0.221079,0.00126609,0.547383 beta-lactamase_W227W,beta-lactamase_227,TEM-1,beta-lactamase,P62593,,YES,227,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-0.982,-0.982,,4.86393,0.272,,B,0.99,-0.29,1.37,,74.48,OHH,-1.595,0.221079,0.00226019,0.344838 beta-lactamase_W286A,beta-lactamase_286,TEM-1,beta-lactamase,P62593,,YES,286,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-1.111,-3.345,2.234,6.64456,0.492,,?,0.01,0.6,,,,BHX,-1.478,0.221079,,0.458068 beta-lactamase_W286W,beta-lactamase_286,TEM-1,beta-lactamase,P62593,,YES,286,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-1.111,-1.111,,6.64456,0.492,,?,0.01,0.6,,,,BHX,-1.478,0.221079,,0.495437 beta-lactamase_X287A,beta-lactamase_287,TEM-1,beta-lactamase,P62593,,YES,287,X,A,XA,Stop,Hydrophobic,5.71,6,0.29,,132.5,89,-43,141.9,88.6,-53.3,,,,,,,,,,,,,HXO,-1.111,0.221079,,0.812973 beta-lactamase_X287H,beta-lactamase_287,TEM-1,beta-lactamase,P62593,,YES,287,X,H,XH,Stop,PositiveCharge,5.71,7.59,1.88,,132.5,155,22,141.9,153.2,11.3,,,,,,,,,,,,,HXO,-1.111,0.221079,,0.810263 beta-lactamase_X287P,beta-lactamase_287,TEM-1,beta-lactamase,P62593,,YES,287,X,P,XP,Stop,Special,5.71,6.3,0.59,,132.5,115,-17,141.9,112.7,-29.2,,,,,,,,,,,,,HXO,-1.111,0.221079,,0.538271 beta-lactamase_X287Q,beta-lactamase_287,TEM-1,beta-lactamase,P62593,,YES,287,X,Q,XQ,Stop,Polar,5.71,6.24429,0.534286,,132.5,146,13,141.9,143.8,1.9,,,,,,,,,,,,,HXO,-1.111,0.221079,,0.808259 beta-lactamase_X287S,beta-lactamase_287,TEM-1,beta-lactamase,P62593,,YES,287,X,S,XS,Stop,Polar,5.71,5.68,-0.03,,132.5,105,-27,141.9,89,-52.9,,,,,,,,,,,,,HXO,-1.111,0.221079,,0.814305 beta-lactamase_X287W,beta-lactamase_287,TEM-1,beta-lactamase,P62593,,YES,287,X,W,XW,Stop,Hydrophobic,5.71,5.89,0.18,,132.5,204,71,141.9,227.8,85.9,,,,,,,,,,,,,HXO,-1.111,0.221079,,0.790764 beta-lactamase_Y260M,beta-lactamase_260,TEM-1,beta-lactamase,P62593,,YES,260,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-1.101,-4.403,3.302,5.50878,,E,B,0.73,-1.04,0.865,,60.49,HHP,-1.83433,0.221079,0.00471757,0.475388 beta-lactamase_Y260Y,beta-lactamase_260,TEM-1,beta-lactamase,P62593,,YES,260,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-1.101,-1.101,,5.50878,,E,B,0.73,-1.04,0.865,,60.49,HHP,-1.83433,0.221079,0.00471757,0.506949 E1_Ubiquitin_G76K,E1_Ubiquitin_76,Uba1,E1_Ubiquitin,P0CG63,,YES,76,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.999,-3.603,2.604,,0.23,,B,0.75,0.08,1.702,,83.73,OOO,-0.999,0.18783,0.00125575,0.633143 E1_Ubiquitin_G76M,E1_Ubiquitin_76,Uba1,E1_Ubiquitin,P0CG63,,YES,76,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.999,-4.67,3.671,,0.23,,B,0.75,0.08,1.702,,83.73,OOO,-0.999,0.18783,0.00125575,0.670976 E1_Ubiquitin_K48K,E1_Ubiquitin_48,Uba1,E1_Ubiquitin,P0CG63,,YES,48,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.219,-1.219,,,0.132,E,B,,-0.28,,,,OBO,-1.109,0.18783,0.00100363,0.844855 E1_Ubiquitin_L69A,E1_Ubiquitin_69,Uba1,E1_Ubiquitin,P0CG63,,YES,69,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.039,-2.895,1.856,,0.051,E,B,,-0.94,,,,PHB,-1.1995,0.18783,0.00182435,0.783498 E1_Ubiquitin_L69C,E1_Ubiquitin_69,Uba1,E1_Ubiquitin,P0CG63,,YES,69,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.039,-4.454,3.415,,0.051,E,B,,-0.94,,,,PHB,-1.1995,0.18783,0.00182435,0.777016 E1_Ubiquitin_L69D,E1_Ubiquitin_69,Uba1,E1_Ubiquitin,P0CG63,,YES,69,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.039,-3.961,2.922,,0.051,E,B,,-0.94,,,,PHB,-1.1995,0.18783,0.00182435,0.756907 E1_Ubiquitin_L69E,E1_Ubiquitin_69,Uba1,E1_Ubiquitin,P0CG63,,YES,69,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.039,-3.707,2.668,,0.051,E,B,,-0.94,,,,PHB,-1.1995,0.18783,0.00182435,0.749039 E1_Ubiquitin_L69F,E1_Ubiquitin_69,Uba1,E1_Ubiquitin,P0CG63,,YES,69,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.039,-3.434,2.395,,0.051,E,B,,-0.94,,,,PHB,-1.1995,0.18783,0.00182435,0.784449 E1_Ubiquitin_L69G,E1_Ubiquitin_69,Uba1,E1_Ubiquitin,P0CG63,,YES,69,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.039,-3.625,2.586,,0.051,E,B,,-0.94,,,,PHB,-1.1995,0.18783,0.00182435,0.752677 E1_Ubiquitin_L69H,E1_Ubiquitin_69,Uba1,E1_Ubiquitin,P0CG63,,YES,69,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.039,-4.722,3.683,,0.051,E,B,,-0.94,,,,PHB,-1.1995,0.18783,0.00182435,0.771151 E1_Ubiquitin_L69I,E1_Ubiquitin_69,Uba1,E1_Ubiquitin,P0CG63,,YES,69,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.039,-2.702,1.663,,0.051,E,B,,-0.94,,,,PHB,-1.1995,0.18783,0.00182435,0.782569 E1_Ubiquitin_L69K,E1_Ubiquitin_69,Uba1,E1_Ubiquitin,P0CG63,,YES,69,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.039,-3.499,2.46,,0.051,E,B,,-0.94,,,,PHB,-1.1995,0.18783,0.00182435,0.761286 E1_Ubiquitin_L69L,E1_Ubiquitin_69,Uba1,E1_Ubiquitin,P0CG63,,YES,69,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.039,-1.039,,,0.051,E,B,,-0.94,,,,PHB,-1.1995,0.18783,0.00182435,0.782569 E1_Ubiquitin_L69M,E1_Ubiquitin_69,Uba1,E1_Ubiquitin,P0CG63,,YES,69,L,M,LM,Hydrophobic,Hydrophobic,9.7088,5.74,-3.9688,15,131,149,18,166.7,162.9,-3.8,-1.039,-3.622,2.583,,0.051,E,B,,-0.94,,,,PHB,-1.1995,0.18783,0.00182435,0.787692 E1_Ubiquitin_L69N,E1_Ubiquitin_69,Uba1,E1_Ubiquitin,P0CG63,,YES,69,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.039,-3.94,2.901,,0.051,E,B,,-0.94,,,,PHB,-1.1995,0.18783,0.00182435,0.763314 E1_Ubiquitin_L69P,E1_Ubiquitin_69,Uba1,E1_Ubiquitin,P0CG63,,YES,69,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.039,-3.922,2.883,,0.051,E,B,,-0.94,,,,PHB,-1.1995,0.18783,0.00182435,0.661531 E1_Ubiquitin_L69Q,E1_Ubiquitin_69,Uba1,E1_Ubiquitin,P0CG63,,YES,69,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.039,-3.941,2.902,,0.051,E,B,,-0.94,,,,PHB,-1.1995,0.18783,0.00182435,0.765023 E1_Ubiquitin_L69R,E1_Ubiquitin_69,Uba1,E1_Ubiquitin,P0CG63,,YES,69,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.039,-3.75,2.711,,0.051,E,B,,-0.94,,,,PHB,-1.1995,0.18783,0.00182435,0.758799 E1_Ubiquitin_L69S,E1_Ubiquitin_69,Uba1,E1_Ubiquitin,P0CG63,,YES,69,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.039,-3.428,2.389,,0.051,E,B,,-0.94,,,,PHB,-1.1995,0.18783,0.00182435,0.761996 E1_Ubiquitin_L69T,E1_Ubiquitin_69,Uba1,E1_Ubiquitin,P0CG63,,YES,69,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.039,-3.239,2.2,,0.051,E,B,,-0.94,,,,PHB,-1.1995,0.18783,0.00182435,0.795369 E1_Ubiquitin_L69V,E1_Ubiquitin_69,Uba1,E1_Ubiquitin,P0CG63,,YES,69,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.039,-2.671,1.632,,0.051,E,B,,-0.94,,,,PHB,-1.1995,0.18783,0.00182435,0.78401 E1_Ubiquitin_L69W,E1_Ubiquitin_69,Uba1,E1_Ubiquitin,P0CG63,,YES,69,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.039,-4.915,3.876,,0.051,E,B,,-0.94,,,,PHB,-1.1995,0.18783,0.00182435,0.793759 E1_Ubiquitin_L69Y,E1_Ubiquitin_69,Uba1,E1_Ubiquitin,P0CG63,,YES,69,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.039,-3.755,2.716,,0.051,E,B,,-0.94,,,,PHB,-1.1995,0.18783,0.00182435,0.78104 E1_Ubiquitin_T68H,E1_Ubiquitin_68,Uba1,E1_Ubiquitin,P0CG63,,YES,68,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,,-3.517,2.167,,,,,,,,,,OPH,-1.039,0.18783,0.00314321,0.889484 E1_Ubiquitin_T68W,E1_Ubiquitin_68,Uba1,E1_Ubiquitin,P0CG63,,YES,68,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,,,,,,,,,,,,,OPH,-1.039,0.18783,0.00314321,0.879509 gb1_A246A,gb1_246,gb1,gb1,P06654,,YES,246,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.175,-1.175,,,,,,,,,,,AHH,-1.87033,0.177985,0.00190625,0.73916 gb1_A249A,gb1_249,gb1,gb1,P06654,,YES,249,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.739,-1.739,,,,,,,,0.252,,44.87,AHH,-1.67367,0.177985,0.00333585,0.646942 gb1_A250A,gb1_250,gb1,gb1,P06654,,YES,250,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.713,-1.713,,,,,,,,3.465,,45.54,HHP,-1.74867,0.177985,0.00332003,0.841855 gb1_A252A,gb1_252,gb1,gb1,P06654,,YES,252,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.175,-1.175,,,,,,,,,,,PHA,-1.55967,0.177985,0.00125598,0.69714 gb1_A260A,gb1_260,gb1,gb1,P06654,,YES,260,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.486,-1.486,,,,,,,,0.173,,9.6,HHP,-1.70967,0.177985,0.0055808,0.61031 gb1_A274A,gb1_274,gb1,gb1,P06654,,YES,274,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.728,-1.728,,,,,,,,4.162,4.162,11.83,AHP,-1.81767,0.177985,0.0068419,0.718149 gb1_D248D,gb1_248,gb1,gb1,P06654,,YES,248,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.569,-1.569,,,,,,,,0.344,,11.83,HAH,-1.673,0.177985,0.001865,0.82963 gb1_D262D,gb1_262,gb1,gb1,P06654,,YES,262,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-3.132,-3.132,,,,,,,,1.304,,45.54,PAP,-2.05233,0.177985,0.00413102,0.892651 gb1_D266D,gb1_266,gb1,gb1,P06654,,YES,266,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.261,-1.261,,,,,,,,0.638,,45.54,HAO,-1.59333,0.177985,0.00394694,0.879346 gb1_D272D,gb1_272,gb1,gb1,P06654,,YES,272,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.457,-1.457,,,,,,,,0.234,,11.83,HAA,-1.54533,0.177985,0.00218257,0.785605 gb1_D273D,gb1_273,gb1,gb1,P06654,,YES,273,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.998,-1.998,,,,,,,,3.514,3.514,37.28,AAH,-1.72767,0.177985,0.00318903,0.88221 gb1_E241E,gb1_241,gb1,gb1,P06654,,YES,241,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.672,-1.672,,,,,,,,0.344,,11.83,OAP,-1.27933,0.177985,0.00250604,0.831306 gb1_E245E,gb1_245,gb1,gb1,P06654,,YES,245,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.725,-2.725,,,,,,,,0.712,,45.54,PAH,-1.84567,0.177985,0.00158611,0.899081 gb1_E253E,gb1_253,gb1,gb1,P06654,,YES,253,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.71,-1.71,,,,,,,,0.529,,11.83,HAB,-1.54433,0.177985,0.00141452,0.339344 gb1_E268E,gb1_268,gb1,gb1,P06654,,YES,268,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.918,-1.918,,,,,,,,0.637,,37.28,OAH,-1.59733,0.177985,0.00423953,0.859537 gb1_E282E,gb1_282,gb1,gb1,P06654,,YES,282,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.318,-1.318,,,,,,,,1.075,,35.71,PAO,-1.573,0.177985,0.00209643,0.709536 gb1_F256F,gb1_256,gb1,gb1,P06654,,YES,256,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.241,-1.241,,,,,,,,,,,HHB,-2.04767,0.177985,0.00435993,0.693734 gb1_F278F,gb1_278,gb1,gb1,P06654,,YES,278,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.418,-1.418,,,,,,,,3.233,,35.71,PHP,-1.503,0.177985,0.00295699,0.570982 gb1_G235G,gb1_235,gb1,gb1,P06654,,YES,235,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.419,-1.419,,,,,,,,0.476,,11.83,POB,-1.86433,0.177985,0.00297491,0.715049 gb1_G240G,gb1_240,gb1,gb1,P06654,,YES,240,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.921,-0.921,,,,,,,,,,,BOA,-1.87867,0.177985,0.00270792,0.687973 gb1_G264G,gb1_264,gb1,gb1,P06654,,YES,264,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.833,-1.833,,,,,,,,0.864,,44.87,POH,-1.61267,0.177985,0.0049716,0.686085 gb1_G267G,gb1_267,gb1,gb1,P06654,,YES,267,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.676,-1.676,,,,,,,,1.361,,12.72,AOA,-1.61833,0.177985,0.00264655,0.442354 gb1_I232I,gb1_232,gb1,gb1,P06654,,YES,232,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-2.175,-2.175,,,,,,,,0.766,,44.87,HHH,-2.152,0.177985,0.00580459,0.821791 gb1_K230K,gb1_230,gb1,gb1,P06654,,YES,230,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.701,-1.701,,,,,,,,0.166,,11.83,HBH,-1.52867,0.177985,0.00331703,0.70267 gb1_K236K,gb1_236,gb1,gb1,P06654,,YES,236,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-2.119,-2.119,,,,,,,,1.083,,45.54,OBP,-1.758,0.177985,0.00255408,0.903237 gb1_K239K,gb1_239,gb1,gb1,P06654,,YES,239,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-3.043,-3.043,,,,,,,,1.326,,45.54,HBO,-2.31467,0.177985,0.00207004,0.89928 gb1_K254K,gb1_254,gb1,gb1,P06654,,YES,254,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.748,-1.748,,,,,,,,1.793,,37.28,ABH,-2.195,0.177985,0.00622711,0.488472 gb1_K257K,gb1_257,gb1,gb1,P06654,,YES,257,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.775,-1.775,,,,,,,,0.896,,37.28,HBP,-1.70367,0.177985,0.00640304,0.429098 gb1_K276K,gb1_276,gb1,gb1,P06654,,YES,276,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.456,-1.456,,,,,,,,0.236,,12.72,PBP,-1.65133,0.177985,0.00620493,0.779124 gb1_L231L,gb1_231,gb1,gb1,P06654,,YES,231,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.603,-1.603,,,,,,,,0.219,,11.83,BHH,-1.82633,0.177985,0.00322797,0.729693 gb1_L233L,gb1_233,gb1,gb1,P06654,,YES,233,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-2.678,-2.678,,,,,,,,0.822,,45.54,HHP,-2.30267,0.177985,0.00266958,0.815 gb1_L238L,gb1_238,gb1,gb1,P06654,,YES,238,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-2.98,-2.98,,,,,,,,0.504,,45.54,PHB,-2.58633,0.177985,0.00205885,0.764467 gb1_N234N,gb1_234,gb1,gb1,P06654,,YES,234,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-2.055,-2.055,,,,,,,,1.235,,45.54,HPO,-2.05067,0.177985,0.00242189,0.883663 gb1_N261N,gb1_261,gb1,gb1,P06654,,YES,261,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-1.863,-1.863,,,,,,,,1.191,,44.87,HPA,-2.16033,0.177985,0.0061875,0.473266 gb1_N263N,gb1_263,gb1,gb1,P06654,,YES,263,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-1.162,-1.162,,,,,,,,,,,APO,-2.04233,0.177985,0.0035297,0.70625 gb1_Q228Q,gb1_228,gb1,gb1,P06654,,YES,228,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,,,,,,,,,,,,,OPH,-1.282,0.177985,0.00391043,0.876178 gb1_Q258Q,gb1_258,gb1,gb1,P06654,,YES,258,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.095,-2.095,,,,,,,,0.86,,37.28,BPH,-1.88333,0.177985,0.00437595,0.825549 gb1_T237T,gb1_237,gb1,gb1,P06654,,YES,237,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.736,-1.736,,,,,,,,0.218,,11.83,BPH,-2.27833,0.177985,0.00275316,0.708206 gb1_T242T,gb1_242,gb1,gb1,P06654,,YES,242,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.245,-1.245,,,,,,,,,,,APP,-1.444,0.177985,0.00243886,0.774131 gb1_T243T,gb1_243,gb1,gb1,P06654,,YES,243,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.415,-1.415,,,,,,,,1.083,,37.28,PPP,-1.43233,0.177985,0.00308687,0.830763 gb1_T244T,gb1_244,gb1,gb1,P06654,,YES,244,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.637,-1.637,,,,,,,,0.202,,11.83,PPA,-1.92567,0.177985,0.00222755,0.802497 gb1_T251T,gb1_251,gb1,gb1,P06654,,YES,251,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.794,-1.794,,,,,,,,3.514,3.514,37.28,HPH,-1.56067,0.177985,0.00232932,0.807798 gb1_T270T,gb1_270,gb1,gb1,P06654,,YES,270,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-3.15,-3.15,,,,,,,,1.326,,45.54,HPH,-1.843,0.177985,0.00223707,0.891428 gb1_T275T,gb1_275,gb1,gb1,P06654,,YES,275,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.727,-1.727,,,,,,,,0.511,,35.71,HPB,-1.637,0.177985,0.00606618,0.770048 gb1_T277T,gb1_277,gb1,gb1,P06654,,YES,277,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.771,-1.771,,,,,,,,0.824,,35.71,BPH,-1.54833,0.177985,0.00348258,0.76795 gb1_T279T,gb1_279,gb1,gb1,P06654,,YES,279,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.32,-1.32,,,,,,,,0.529,,35.71,HPH,-1.50067,0.177985,0.00421454,0.821749 gb1_T281T,gb1_281,gb1,gb1,P06654,,YES,281,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.828,-1.828,,,,,,,,1.038,,35.71,HPA,-1.63667,0.177985,0.00284418,0.76747 gb1_V247V,gb1_247,gb1,gb1,P06654,,YES,247,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.711,-1.711,,,,,,,,0.805,,44.87,HHA,-1.485,0.177985,0.00435373,0.724484 gb1_V255V,gb1_255,gb1,gb1,P06654,,YES,255,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-3.127,-3.127,,,,,,,,1.323,,45.54,BHH,-2.03867,0.177985,0.00408354,0.876998 gb1_V265V,gb1_265,gb1,gb1,P06654,,YES,265,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.843,-1.843,,,,,,,,0.402,,11.83,OHA,-1.64567,0.177985,0.00360613,0.67505 gb1_V280V,gb1_280,gb1,gb1,P06654,,YES,280,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.764,-1.764,,,,,,,,0.874,,35.71,PHP,-1.63733,0.177985,0.00321577,0.630797 gb1_W269W,gb1_269,gb1,gb1,P06654,,YES,269,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,-1.198,-1.198,,,,,,,,,,,AHP,-2.08867,0.177985,0.00270706,0.370876 gb1_Y229Y,gb1_229,gb1,gb1,P06654,,YES,229,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-1.282,-1.282,,,,,,,,,,,PHB,-1.4915,0.177985,0.00366605,0.714607 gb1_Y259Y,gb1_259,gb1,gb1,P06654,,YES,259,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-1.78,-1.78,,,,,,,,0.131,,11.83,PHH,-1.787,0.177985,0.00464313,0.678817 gb1_Y271Y,gb1_271,gb1,gb1,P06654,,YES,271,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-1.181,-1.181,,,,,,,,,,,PHA,-1.92933,0.177985,0.00236544,0.676538 kka2_1:1_A108K,kka2_1:1_108,Kka2,kka2_1:1,P00552,,YES,108,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.061,-3.668,1.607,,0.243,.,B,0.46,-1.34,3.156,,71.59,HHO,-1.57033,0.520039,0.00751209,0.605536 kka2_1:1_A110C,kka2_1:1_110,Kka2,kka2_1:1,P00552,,YES,110,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.064,-5.167,3.103,,0.175,H,A,1.04,-1.19,11.755,,71.59,OHA,-1.91867,0.520039,0.00759851,0.712027 kka2_1:1_A117I,kka2_1:1_117,Kka2,kka2_1:1,P00552,,YES,117,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.828,-3.432,2.604,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.520039,0.00282984,0.39758 kka2_1:1_A119F,kka2_1:1_119,Kka2,kka2_1:1,P00552,,YES,119,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.073,-4.171,3.098,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.520039,0.00441074,0.436957 kka2_1:1_A119H,kka2_1:1_119,Kka2,kka2_1:1,P00552,,YES,119,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.073,-4.774,3.701,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.520039,0.00441074,0.472881 kka2_1:1_A119I,kka2_1:1_119,Kka2,kka2_1:1,P00552,,YES,119,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.073,-3.591,2.518,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.520039,0.00441074,0.42637 kka2_1:1_A119N,kka2_1:1_119,Kka2,kka2_1:1,P00552,,YES,119,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.073,-3.831,2.758,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.520039,0.00441074,0.426048 kka2_1:1_A129C,kka2_1:1_129,Kka2,kka2_1:1,P00552,,YES,129,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.656,-5.053,3.397,,0.845,G,A,0.46,0.72,19.686,19.686,92.05,OHP,-1.99,0.520039,0.00726862,0.80778 kka2_1:1_A129F,kka2_1:1_129,Kka2,kka2_1:1,P00552,,YES,129,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.656,-4.391,2.735,,0.845,G,A,0.46,0.72,19.686,19.686,92.05,OHP,-1.99,0.520039,0.00726862,0.818999 kka2_1:1_A129H,kka2_1:1_129,Kka2,kka2_1:1,P00552,,YES,129,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.656,-3.201,1.545,,0.845,G,A,0.46,0.72,19.686,19.686,92.05,OHP,-1.99,0.520039,0.00726862,0.814673 kka2_1:1_A129K,kka2_1:1_129,Kka2,kka2_1:1,P00552,,YES,129,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.656,-3.023,1.367,,0.845,G,A,0.46,0.72,19.686,19.686,92.05,OHP,-1.99,0.520039,0.00726862,0.825032 kka2_1:1_A129N,kka2_1:1_129,Kka2,kka2_1:1,P00552,,YES,129,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.656,-2.9,1.244,,0.845,G,A,0.46,0.72,19.686,19.686,92.05,OHP,-1.99,0.520039,0.00726862,0.823202 kka2_1:1_A129R,kka2_1:1_129,Kka2,kka2_1:1,P00552,,YES,129,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.656,-2.972,1.316,,0.845,G,A,0.46,0.72,19.686,19.686,92.05,OHP,-1.99,0.520039,0.00726862,0.828901 kka2_1:1_A129Y,kka2_1:1_129,Kka2,kka2_1:1,P00552,,YES,129,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.656,-4.374,2.718,,0.845,G,A,0.46,0.72,19.686,19.686,92.05,OHP,-1.99,0.520039,0.00726862,0.819587 kka2_1:1_A13H,kka2_1:1_13,Kka2,kka2_1:1,P00552,,YES,13,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.248,-3.721,1.473,,0.689,G,A,0.46,0.99,25.015,25.015,92.05,OHH,-1.646,0.520039,0.00784241,0.896825 kka2_1:1_A13K,kka2_1:1_13,Kka2,kka2_1:1,P00552,,YES,13,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.248,-3.012,0.764,,0.689,G,A,0.46,0.99,25.015,25.015,92.05,OHH,-1.646,0.520039,0.00784241,0.899548 kka2_1:1_A13L,kka2_1:1_13,Kka2,kka2_1:1,P00552,,YES,13,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.248,-2.945,0.697,,0.689,G,A,0.46,0.99,25.015,25.015,92.05,OHH,-1.646,0.520039,0.00784241,0.888759 kka2_1:1_A13N,kka2_1:1_13,Kka2,kka2_1:1,P00552,,YES,13,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.248,-3.116,0.868,,0.689,G,A,0.46,0.99,25.015,25.015,92.05,OHH,-1.646,0.520039,0.00784241,0.924088 kka2_1:1_A13Y,kka2_1:1_13,Kka2,kka2_1:1,P00552,,YES,13,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.248,-4.443,2.195,,0.689,G,A,0.46,0.99,25.015,25.015,92.05,OHH,-1.646,0.520039,0.00784241,0.939691 kka2_1:1_A144I,kka2_1:1_144,Kka2,kka2_1:1,P00552,,YES,144,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.859,-3.396,2.537,,,H,A,0.46,0.21,0.842,,52.65,BHB,-1.72933,0.520039,0.00231095,0.424157 kka2_1:1_A144P,kka2_1:1_144,Kka2,kka2_1:1,P00552,,YES,144,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.859,-3.765,2.906,,,H,A,0.46,0.21,0.842,,52.65,BHB,-1.72933,0.520039,0.00231095,0.462616 kka2_1:1_A14C,kka2_1:1_14,Kka2,kka2_1:1,P00552,,YES,14,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.837,-5.018,3.181,,0.728,G,A,0.46,0.7,1.17,,71.59,HHH,-1.82567,0.520039,0.00706614,0.828699 kka2_1:1_A14F,kka2_1:1_14,Kka2,kka2_1:1,P00552,,YES,14,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.837,-4.392,2.555,,0.728,G,A,0.46,0.7,1.17,,71.59,HHH,-1.82567,0.520039,0.00706614,0.789354 kka2_1:1_A14N,kka2_1:1_14,Kka2,kka2_1:1,P00552,,YES,14,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.837,-3.807,1.97,,0.728,G,A,0.46,0.7,1.17,,71.59,HHH,-1.82567,0.520039,0.00706614,0.782585 kka2_1:1_A14R,kka2_1:1_14,Kka2,kka2_1:1,P00552,,YES,14,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.837,-2.714,0.877,,0.728,G,A,0.46,0.7,1.17,,71.59,HHH,-1.82567,0.520039,0.00706614,0.809858 kka2_1:1_A150C,kka2_1:1_150,Kka2,kka2_1:1,P00552,,YES,150,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.949,-4.673,3.724,,0.544,T,A,0.46,1.34,2.333,,63.26,AHO,-1.272,0.520039,0.0045009,0.712351 kka2_1:1_A150Y,kka2_1:1_150,Kka2,kka2_1:1,P00552,,YES,150,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.949,-4.269,3.32,,0.544,T,A,0.46,1.34,2.333,,63.26,AHO,-1.272,0.520039,0.0045009,0.630571 kka2_1:1_A168I,kka2_1:1_168,Kka2,kka2_1:1,P00552,,YES,168,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.989,-4.068,2.079,,0.67,H,A,0.46,0.15,25.546,25.546,64.39,OHA,-2.12933,0.520039,0.00806773,0.762586 kka2_1:1_A224C,kka2_1:1_224,Kka2,kka2_1:1,P00552,,YES,224,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.977,-4.591,3.614,,,H,A,0.46,-1.26,1.725,,63.64,HHP,-1.41033,0.520039,0.00352047,0.505498 kka2_1:1_A224I,kka2_1:1_224,Kka2,kka2_1:1,P00552,,YES,224,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.977,-3.567,2.59,,,H,A,0.46,-1.26,1.725,,63.64,HHP,-1.41033,0.520039,0.00352047,0.391142 kka2_1:1_A237F,kka2_1:1_237,Kka2,kka2_1:1,P00552,,YES,237,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.12,-4.013,1.893,,0.068,H,A,0.46,-0.71,2.369,,92.05,HHA,-2.10433,0.520039,0.012257,0.45233 kka2_1:1_A237H,kka2_1:1_237,Kka2,kka2_1:1,P00552,,YES,237,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.12,-4.997,2.877,,0.068,H,A,0.46,-0.71,2.369,,92.05,HHA,-2.10433,0.520039,0.012257,0.539234 kka2_1:1_A237Y,kka2_1:1_237,Kka2,kka2_1:1,P00552,,YES,237,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.12,-4.178,2.058,,0.068,H,A,0.46,-0.71,2.369,,92.05,HHA,-2.10433,0.520039,0.012257,0.467865 kka2_1:1_A247F,kka2_1:1_247,Kka2,kka2_1:1,P00552,,YES,247,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.459,-3.316,0.857,,1.01,S,A,0.46,0.65,7.731,7.731,92.05,HHH,-2.197,0.520039,0.0102428,0.905171 kka2_1:1_A247H,kka2_1:1_247,Kka2,kka2_1:1,P00552,,YES,247,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.459,-3.473,1.014,,1.01,S,A,0.46,0.65,7.731,7.731,92.05,HHH,-2.197,0.520039,0.0102428,0.916977 kka2_1:1_A248C,kka2_1:1_248,Kka2,kka2_1:1,P00552,,YES,248,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.124,-5.173,3.049,,0.825,S,b,0.46,0.46,24.72,24.72,92.05,HHO,-2.15,0.520039,0.0125484,0.860412 kka2_1:1_A248F,kka2_1:1_248,Kka2,kka2_1:1,P00552,,YES,248,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.124,-4.425,2.301,,0.825,S,b,0.46,0.46,24.72,24.72,92.05,HHO,-2.15,0.520039,0.0125484,0.887773 kka2_1:1_A248H,kka2_1:1_248,Kka2,kka2_1:1,P00552,,YES,248,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.124,-3.589,1.465,,0.825,S,b,0.46,0.46,24.72,24.72,92.05,HHO,-2.15,0.520039,0.0125484,0.879433 kka2_1:1_A248I,kka2_1:1_248,Kka2,kka2_1:1,P00552,,YES,248,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.124,-3.04,0.916,,0.825,S,b,0.46,0.46,24.72,24.72,92.05,HHO,-2.15,0.520039,0.0125484,0.857808 kka2_1:1_A248N,kka2_1:1_248,Kka2,kka2_1:1,P00552,,YES,248,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.124,-3.883,1.759,,0.825,S,b,0.46,0.46,24.72,24.72,92.05,HHO,-2.15,0.520039,0.0125484,0.846424 kka2_1:1_A248Q,kka2_1:1_248,Kka2,kka2_1:1,P00552,,YES,248,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.124,-2.728,0.604,,0.825,S,b,0.46,0.46,24.72,24.72,92.05,HHO,-2.15,0.520039,0.0125484,0.88128 kka2_1:1_A248Y,kka2_1:1_248,Kka2,kka2_1:1,P00552,,YES,248,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.124,-4.406,2.282,,0.825,S,b,0.46,0.46,24.72,24.72,92.05,HHO,-2.15,0.520039,0.0125484,0.905941 kka2_1:1_A25I,kka2_1:1_25,Kka2,kka2_1:1,P00552,,YES,25,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.496,-3.984,1.488,,0.427,E,B,0.46,-0.47,6.872,6.872,65.53,HHP,-2.15167,0.520039,0.00595636,0.642281 kka2_1:1_A25K,kka2_1:1_25,Kka2,kka2_1:1,P00552,,YES,25,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.496,-2.905,0.409,,0.427,E,B,0.46,-0.47,6.872,6.872,65.53,HHP,-2.15167,0.520039,0.00595636,0.825106 kka2_1:1_A25Y,kka2_1:1_25,Kka2,kka2_1:1,P00552,,YES,25,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.496,-4.311,1.815,,0.427,E,B,0.46,-0.47,6.872,6.872,65.53,HHP,-2.15167,0.520039,0.00595636,0.67833 kka2_1:1_A34H,kka2_1:1_34,Kka2,kka2_1:1,P00552,,YES,34,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.928,-4.681,3.753,,0.417,.,B,0.46,2.29,0.262,,52.27,AHH,-1.747,0.520039,0.00343484,0.428778 kka2_1:1_A34I,kka2_1:1_34,Kka2,kka2_1:1,P00552,,YES,34,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.928,-3.671,2.743,,0.417,.,B,0.46,2.29,0.262,,52.27,AHH,-1.747,0.520039,0.00343484,0.417429 kka2_1:1_A34K,kka2_1:1_34,Kka2,kka2_1:1,P00552,,YES,34,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.928,-3.458,2.53,,0.417,.,B,0.46,2.29,0.262,,52.27,AHH,-1.747,0.520039,0.00343484,0.454857 kka2_1:1_A34N,kka2_1:1_34,Kka2,kka2_1:1,P00552,,YES,34,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.928,-3.748,2.82,,0.417,.,B,0.46,2.29,0.262,,52.27,AHH,-1.747,0.520039,0.00343484,0.420569 kka2_1:1_A35F,kka2_1:1_35,Kka2,kka2_1:1,P00552,,YES,35,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.127,-4.402,2.275,,0.107,E,B,0.46,1.05,8.405,8.405,71.59,HHH,-1.31767,0.520039,0.00630016,0.725747 kka2_1:1_A35H,kka2_1:1_35,Kka2,kka2_1:1,P00552,,YES,35,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.127,-3.517,1.39,,0.107,E,B,0.46,1.05,8.405,8.405,71.59,HHH,-1.31767,0.520039,0.00630016,0.772769 kka2_1:1_A35I,kka2_1:1_35,Kka2,kka2_1:1,P00552,,YES,35,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.127,-4.036,1.909,,0.107,E,B,0.46,1.05,8.405,8.405,71.59,HHH,-1.31767,0.520039,0.00630016,0.728478 kka2_1:1_A35N,kka2_1:1_35,Kka2,kka2_1:1,P00552,,YES,35,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.127,-2.713,0.586,,0.107,E,B,0.46,1.05,8.405,8.405,71.59,HHH,-1.31767,0.520039,0.00630016,0.843019 kka2_1:1_A35R,kka2_1:1_35,Kka2,kka2_1:1,P00552,,YES,35,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.127,-3.236,1.109,,0.107,E,B,0.46,1.05,8.405,8.405,71.59,HHH,-1.31767,0.520039,0.00630016,0.786793 kka2_1:1_A35Y,kka2_1:1_35,Kka2,kka2_1:1,P00552,,YES,35,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.127,-4.416,2.289,,0.107,E,B,0.46,1.05,8.405,8.405,71.59,HHH,-1.31767,0.520039,0.00630016,0.736999 kka2_1:1_A41K,kka2_1:1_41,Kka2,kka2_1:1,P00552,,YES,41,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.879,-3.682,1.803,,0.184,.,B,0.46,-0.96,18.207,18.207,64.39,PHP,-2.477,0.520039,0.00543332,0.583863 kka2_1:1_A56K,kka2_1:1_56,Kka2,kka2_1:1,P00552,,YES,56,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.083,-3.671,1.588,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.520039,0.00717715,0.814696 kka2_1:1_A56Y,kka2_1:1_56,Kka2,kka2_1:1,P00552,,YES,56,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.083,-4.486,2.403,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.520039,0.00717715,0.875056 kka2_1:1_A64F,kka2_1:1_64,Kka2,kka2_1:1,P00552,,YES,64,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.496,-4.09,2.594,,0.039,H,A,0.46,-0.57,1.175,,56.06,AHH,-1.334,0.520039,0.00705578,0.478025 kka2_1:1_A64I,kka2_1:1_64,Kka2,kka2_1:1,P00552,,YES,64,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.496,-1.939,0.443,,0.039,H,A,0.46,-0.57,1.175,,56.06,AHH,-1.334,0.520039,0.00705578,0.62646 kka2_1:1_A64Q,kka2_1:1_64,Kka2,kka2_1:1,P00552,,YES,64,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.496,-4.195,2.699,,0.039,H,A,0.46,-0.57,1.175,,56.06,AHH,-1.334,0.520039,0.00705578,0.482721 kka2_1:1_A64W,kka2_1:1_64,Kka2,kka2_1:1,P00552,,YES,64,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.496,-5.479,3.983,,0.039,H,A,0.46,-0.57,1.175,,56.06,AHH,-1.334,0.520039,0.00705578,0.46929 kka2_1:1_A65D,kka2_1:1_65,Kka2,kka2_1:1,P00552,,YES,65,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.744,-2.659,0.915,,0.437,H,A,0.46,-0.39,3.012,,63.64,HHB,-1.38733,0.520039,0.00709258,0.660099 kka2_1:1_A65H,kka2_1:1_65,Kka2,kka2_1:1,P00552,,YES,65,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.744,-3.525,1.781,,0.437,H,A,0.46,-0.39,3.012,,63.64,HHB,-1.38733,0.520039,0.00709258,0.657209 kka2_1:1_A65I,kka2_1:1_65,Kka2,kka2_1:1,P00552,,YES,65,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.744,-3.823,2.079,,0.437,H,A,0.46,-0.39,3.012,,63.64,HHB,-1.38733,0.520039,0.00709258,0.630482 kka2_1:1_A65N,kka2_1:1_65,Kka2,kka2_1:1,P00552,,YES,65,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.744,-3.167,1.423,,0.437,H,A,0.46,-0.39,3.012,,63.64,HHB,-1.38733,0.520039,0.00709258,0.661994 kka2_1:1_A65R,kka2_1:1_65,Kka2,kka2_1:1,P00552,,YES,65,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.744,-3.924,2.18,,0.437,H,A,0.46,-0.39,3.012,,63.64,HHB,-1.38733,0.520039,0.00709258,0.693895 kka2_1:1_A71F,kka2_1:1_71,Kka2,kka2_1:1,P00552,,YES,71,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.824,-4.432,2.608,,0.553,H,A,0.46,0.08,9.788,,64.39,HHP,-1.74033,0.520039,0.00727707,0.695377 kka2_1:1_A71K,kka2_1:1_71,Kka2,kka2_1:1,P00552,,YES,71,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.824,-2.499,0.675,,0.553,H,A,0.46,0.08,9.788,,64.39,HHP,-1.74033,0.520039,0.00727707,0.765279 kka2_1:1_A71P,kka2_1:1_71,Kka2,kka2_1:1,P00552,,YES,71,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.824,-4.026,2.202,,0.553,H,A,0.46,0.08,9.788,,64.39,HHP,-1.74033,0.520039,0.00727707,0.600382 kka2_1:1_A79P,kka2_1:1_79,Kka2,kka2_1:1,P00552,,YES,79,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.368,-3.3,0.932,,0.563,.,B,0.46,-0.43,7.792,7.792,71.59,HHH,-1.752,0.520039,0.00664821,0.821297 kka2_1:1_A87I,kka2_1:1_87,Kka2,kka2_1:1,P00552,,YES,87,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.917,-4.113,2.196,,1.039,S,L,0.46,1.57,20.738,20.738,65.53,AHO,-1.822,0.520039,0.00791281,0.742027 kka2_1:1_A87K,kka2_1:1_87,Kka2,kka2_1:1,P00552,,YES,87,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.917,-3.626,1.709,,1.039,S,L,0.46,1.57,20.738,20.738,65.53,AHO,-1.822,0.520039,0.00791281,0.809211 kka2_1:1_A87M,kka2_1:1_87,Kka2,kka2_1:1,P00552,,YES,87,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.917,-4.877,2.96,,1.039,S,L,0.46,1.57,20.738,20.738,65.53,AHO,-1.822,0.520039,0.00791281,0.81082 kka2_1:1_A87N,kka2_1:1_87,Kka2,kka2_1:1,P00552,,YES,87,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.917,-2.703,0.786,,1.039,S,L,0.46,1.57,20.738,20.738,65.53,AHO,-1.822,0.520039,0.00791281,0.837028 kka2_1:1_A87R,kka2_1:1_87,Kka2,kka2_1:1,P00552,,YES,87,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.917,-3.21,1.293,,1.039,S,L,0.46,1.57,20.738,20.738,65.53,AHO,-1.822,0.520039,0.00791281,0.833938 kka2_1:1_A87W,kka2_1:1_87,Kka2,kka2_1:1,P00552,,YES,87,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.917,-5.563,3.646,,1.039,S,L,0.46,1.57,20.738,20.738,65.53,AHO,-1.822,0.520039,0.00791281,0.756756 kka2_1:1_A87Y,kka2_1:1_87,Kka2,kka2_1:1,P00552,,YES,87,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.917,-4.401,2.484,,1.039,S,L,0.46,1.57,20.738,20.738,65.53,AHO,-1.822,0.520039,0.00791281,0.800638 kka2_1:1_A9H,kka2_1:1_9,Kka2,kka2_1:1,P00552,,YES,9,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.079,-4.629,2.55,,,,,,,0.383,,71.59,BHO,-2.253,0.520039,0.00273264,0.988363 kka2_1:1_A9K,kka2_1:1_9,Kka2,kka2_1:1,P00552,,YES,9,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.079,-3.506,1.427,,,,,,,0.383,,71.59,BHO,-2.253,0.520039,0.00273264,0.993304 kka2_1:1_C131A,kka2_1:1_131,Kka2,kka2_1:1,P00552,,YES,131,C,A,CA,Special,Hydrophobic,5.07,6,0.93,195,121,89,-32,108.5,88.6,-19.9,-0.831,-2.881,2.05,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.520039,0.00170814,0.484594 kka2_1:1_C131D,kka2_1:1_131,Kka2,kka2_1:1,P00552,,YES,131,C,D,CD,Special,negativeCharge,5.07,5.0516,-0.0184,154,121,133,12,108.5,111.1,2.6,-0.831,-3.947,3.116,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.520039,0.00170814,0.449708 kka2_1:1_C131E,kka2_1:1_131,Kka2,kka2_1:1,P00552,,YES,131,C,E,CE,Special,negativeCharge,5.07,3.22,-1.85,170,121,147,26,108.5,138.4,29.9,-0.831,-4.143,3.312,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.520039,0.00170814,0.440501 kka2_1:1_C131H,kka2_1:1_131,Kka2,kka2_1:1,P00552,,YES,131,C,H,CH,Special,PositiveCharge,5.07,7.59,2.52,174,121,155,34,108.5,153.2,44.7,-0.831,-4.933,4.102,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.520039,0.00170814,0.428069 kka2_1:1_C131I,kka2_1:1_131,Kka2,kka2_1:1,P00552,,YES,131,C,I,CI,Special,Hydrophobic,5.07,6.02,0.95,198,121,131,10,108.5,166.7,58.2,-0.831,-3.589,2.758,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.520039,0.00170814,0.451677 kka2_1:1_C131K,kka2_1:1_131,Kka2,kka2_1:1,P00552,,YES,131,C,K,CK,Special,PositiveCharge,5.07,9.74,4.67,202,121,146,25,108.5,168.6,60.1,-0.831,-3.935,3.104,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.520039,0.00170814,0.458796 kka2_1:1_C131M,kka2_1:1_131,Kka2,kka2_1:1,P00552,,YES,131,C,M,CM,Special,Hydrophobic,5.07,5.74,0.67,196,121,149,28,108.5,162.9,54.4,-0.831,-4.508,3.677,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.520039,0.00170814,0.446769 kka2_1:1_C131P,kka2_1:1_131,Kka2,kka2_1:1,P00552,,YES,131,C,P,CP,Special,Special,5.07,6.3,1.23,169,121,115,-6,108.5,112.7,4.2,-0.831,-4.133,3.302,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.520039,0.00170814,0.460115 kka2_1:1_C131Q,kka2_1:1_131,Kka2,kka2_1:1,P00552,,YES,131,C,Q,CQ,Special,Polar,5.07,6.24429,1.17429,154,121,146,25,108.5,143.8,35.3,-0.831,-4.378,3.547,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.520039,0.00170814,0.43785 kka2_1:1_C31A,kka2_1:1_31,Kka2,kka2_1:1,P00552,,YES,31,C,A,CA,Special,Hydrophobic,5.07,6,0.93,195,121,89,-32,108.5,88.6,-19.9,-2.246,-2.378,0.132,,1.152,S,b,0.46,4.16,8.272,,63.26,OOP,-1.21533,0.520039,0.00681582,0.828243 kka2_1:1_C31D,kka2_1:1_31,Kka2,kka2_1:1,P00552,,YES,31,C,D,CD,Special,negativeCharge,5.07,5.0516,-0.0184,154,121,133,12,108.5,111.1,2.6,-2.246,-3.622,1.376,,1.152,S,b,0.46,4.16,8.272,,63.26,OOP,-1.21533,0.520039,0.00681582,0.668766 kka2_1:1_C31H,kka2_1:1_31,Kka2,kka2_1:1,P00552,,YES,31,C,H,CH,Special,PositiveCharge,5.07,7.59,2.52,174,121,155,34,108.5,153.2,44.7,-2.246,-3.333,1.087,,1.152,S,b,0.46,4.16,8.272,,63.26,OOP,-1.21533,0.520039,0.00681582,0.755134 kka2_1:1_C31M,kka2_1:1_31,Kka2,kka2_1:1,P00552,,YES,31,C,M,CM,Special,Hydrophobic,5.07,5.74,0.67,196,121,149,28,108.5,162.9,54.4,-2.246,-4.677,2.431,,1.152,S,b,0.46,4.16,8.272,,63.26,OOP,-1.21533,0.520039,0.00681582,0.673455 kka2_1:1_C31P,kka2_1:1_31,Kka2,kka2_1:1,P00552,,YES,31,C,P,CP,Special,Special,5.07,6.3,1.23,169,121,115,-6,108.5,112.7,4.2,-2.246,-4.029,1.783,,1.152,S,b,0.46,4.16,8.272,,63.26,OOP,-1.21533,0.520039,0.00681582,0.559427 kka2_1:1_C31Q,kka2_1:1_31,Kka2,kka2_1:1,P00552,,YES,31,C,Q,CQ,Special,Polar,5.07,6.24429,1.17429,154,121,146,25,108.5,143.8,35.3,-2.246,-2.477,0.231,,1.152,S,b,0.46,4.16,8.272,,63.26,OOP,-1.21533,0.520039,0.00681582,0.79895 kka2_1:1_D101L,kka2_1:1_101,Kka2,kka2_1:1,P00552,,YES,101,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.028,-3.645,2.617,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.520039,0.00423361,0.459867 kka2_1:1_D101M,kka2_1:1_101,Kka2,kka2_1:1,P00552,,YES,101,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.028,-4.841,3.813,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.520039,0.00423361,0.457916 kka2_1:1_D101P,kka2_1:1_101,Kka2,kka2_1:1,P00552,,YES,101,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.028,-3.843,2.815,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.520039,0.00423361,0.470171 kka2_1:1_D101V,kka2_1:1_101,Kka2,kka2_1:1,P00552,,YES,101,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.028,-2.595,1.567,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.520039,0.00423361,0.597798 kka2_1:1_D101W,kka2_1:1_101,Kka2,kka2_1:1,P00552,,YES,101,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.028,-5.632,4.604,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.520039,0.00423361,0.426707 kka2_1:1_D118A,kka2_1:1_118,Kka2,kka2_1:1,P00552,,YES,118,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.07,-2.21,0.14,,0.61,H,A,0.75,-0.05,13.434,13.434,64.39,HAH,-1.32367,0.520039,0.0067852,0.833812 kka2_1:1_D118C,kka2_1:1_118,Kka2,kka2_1:1,P00552,,YES,118,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.07,-5.162,3.092,,0.61,H,A,0.75,-0.05,13.434,13.434,64.39,HAH,-1.32367,0.520039,0.0067852,0.692204 kka2_1:1_D118G,kka2_1:1_118,Kka2,kka2_1:1,P00552,,YES,118,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.07,-2.786,0.716,,0.61,H,A,0.75,-0.05,13.434,13.434,64.39,HAH,-1.32367,0.520039,0.0067852,0.726636 kka2_1:1_D118M,kka2_1:1_118,Kka2,kka2_1:1,P00552,,YES,118,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.07,-3.354,1.284,,0.61,H,A,0.75,-0.05,13.434,13.434,64.39,HAH,-1.32367,0.520039,0.0067852,0.676092 kka2_1:1_D118S,kka2_1:1_118,Kka2,kka2_1:1,P00552,,YES,118,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.07,-2.544,0.474,,0.61,H,A,0.75,-0.05,13.434,13.434,64.39,HAH,-1.32367,0.520039,0.0067852,0.77433 kka2_1:1_D118W,kka2_1:1_118,Kka2,kka2_1:1,P00552,,YES,118,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.07,-5.579,3.509,,0.61,H,A,0.75,-0.05,13.434,13.434,64.39,HAH,-1.32367,0.520039,0.0067852,0.622566 kka2_1:1_D127C,kka2_1:1_127,Kka2,kka2_1:1,P00552,,YES,127,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.364,-5.181,3.817,,0.573,.,B,0.75,0.45,3.414,,50.38,HAO,-1.51067,0.520039,0.00660501,0.604691 kka2_1:1_D127K,kka2_1:1_127,Kka2,kka2_1:1,P00552,,YES,127,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.364,-3.534,2.17,,0.573,.,B,0.75,0.45,3.414,,50.38,HAO,-1.51067,0.520039,0.00660501,0.604924 kka2_1:1_D127L,kka2_1:1_127,Kka2,kka2_1:1,P00552,,YES,127,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.364,-3.769,2.405,,0.573,.,B,0.75,0.45,3.414,,50.38,HAO,-1.51067,0.520039,0.00660501,0.566151 kka2_1:1_D127M,kka2_1:1_127,Kka2,kka2_1:1,P00552,,YES,127,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.364,-4.921,3.557,,0.573,.,B,0.75,0.45,3.414,,50.38,HAO,-1.51067,0.520039,0.00660501,0.569751 kka2_1:1_D127P,kka2_1:1_127,Kka2,kka2_1:1,P00552,,YES,127,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.364,-1.54,0.176,,0.573,.,B,0.75,0.45,3.414,,50.38,HAO,-1.51067,0.520039,0.00660501,0.750343 kka2_1:1_D127S,kka2_1:1_127,Kka2,kka2_1:1,P00552,,YES,127,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.364,-3.391,2.027,,0.573,.,B,0.75,0.45,3.414,,50.38,HAO,-1.51067,0.520039,0.00660501,0.605726 kka2_1:1_D127T,kka2_1:1_127,Kka2,kka2_1:1,P00552,,YES,127,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.364,-3.566,2.202,,0.573,.,B,0.75,0.45,3.414,,50.38,HAO,-1.51067,0.520039,0.00660501,0.61276 kka2_1:1_D127W,kka2_1:1_127,Kka2,kka2_1:1,P00552,,YES,127,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.364,-5.662,4.298,,0.573,.,B,0.75,0.45,3.414,,50.38,HAO,-1.51067,0.520039,0.00660501,0.540421 kka2_1:1_D134W,kka2_1:1_134,Kka2,kka2_1:1,P00552,,YES,134,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.969,-5.579,4.61,,0.421,B,B,0.75,0.31,2.329,,49.62,HAB,-1.057,0.520039,0.00270812,0.673518 kka2_1:1_D154L,kka2_1:1_154,Kka2,kka2_1:1,P00552,,YES,154,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.876,-3.838,2.962,,0.457,.,b,0.75,1.48,0.658,,52.65,HAP,-1.52467,0.520039,0.00292633,0.641448 kka2_1:1_D154P,kka2_1:1_154,Kka2,kka2_1:1,P00552,,YES,154,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.876,-3.765,2.889,,0.457,.,b,0.75,1.48,0.658,,52.65,HAP,-1.52467,0.520039,0.00292633,0.657134 kka2_1:1_D154W,kka2_1:1_154,Kka2,kka2_1:1,P00552,,YES,154,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.876,-5.609,4.733,,0.457,.,b,0.75,1.48,0.658,,52.65,HAP,-1.52467,0.520039,0.00292633,0.6258 kka2_1:1_D156L,kka2_1:1_156,Kka2,kka2_1:1,P00552,,YES,156,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.696,-3.635,1.939,,0.884,T,A,0.75,1.87,1.044,,65.53,PAA,-1.765,0.520039,0.00926998,0.782106 kka2_1:1_D157L,kka2_1:1_157,Kka2,kka2_1:1,P00552,,YES,157,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.993,-3.843,2.85,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.520039,0.0042313,0.59214 kka2_1:1_D157M,kka2_1:1_157,Kka2,kka2_1:1,P00552,,YES,157,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.993,-4.965,3.972,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.520039,0.0042313,0.635357 kka2_1:1_D157P,kka2_1:1_157,Kka2,kka2_1:1,P00552,,YES,157,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.993,-3.813,2.82,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.520039,0.0042313,0.608318 kka2_1:1_D157W,kka2_1:1_157,Kka2,kka2_1:1,P00552,,YES,157,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.993,-5.591,4.598,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.520039,0.0042313,0.628696 kka2_1:1_D159S,kka2_1:1_159,Kka2,kka2_1:1,P00552,,YES,159,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.82,-3.223,2.403,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.520039,0.0030485,0.53875 kka2_1:1_D180A,kka2_1:1_180,Kka2,kka2_1:1,P00552,,YES,180,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.416,-2.13,-0.286,,1.03,S,a,0.75,1.5,1.534,,71.59,OAO,-2.02933,0.520039,0.00756412,0.918838 kka2_1:1_D180L,kka2_1:1_180,Kka2,kka2_1:1,P00552,,YES,180,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.416,-2.808,0.392,,1.03,S,a,0.75,1.5,1.534,,71.59,OAO,-2.02933,0.520039,0.00756412,0.842533 kka2_1:1_D180M,kka2_1:1_180,Kka2,kka2_1:1,P00552,,YES,180,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.416,-3.738,1.322,,1.03,S,a,0.75,1.5,1.534,,71.59,OAO,-2.02933,0.520039,0.00756412,0.871265 kka2_1:1_D180P,kka2_1:1_180,Kka2,kka2_1:1,P00552,,YES,180,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.416,-3.147,0.731,,1.03,S,a,0.75,1.5,1.534,,71.59,OAO,-2.02933,0.520039,0.00756412,0.79965 kka2_1:1_D190W,kka2_1:1_190,Kka2,kka2_1:1,P00552,,YES,190,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.708,-5.576,4.868,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.520039,0.00247989,0.37043 kka2_1:1_D216A,kka2_1:1_216,Kka2,kka2_1:1,P00552,,YES,216,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.785,-3.354,2.569,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.520039,0.00229969,0.490309 kka2_1:1_D216C,kka2_1:1_216,Kka2,kka2_1:1,P00552,,YES,216,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.785,-5.139,4.354,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.520039,0.00229969,0.505588 kka2_1:1_D216G,kka2_1:1_216,Kka2,kka2_1:1,P00552,,YES,216,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.785,-3.205,2.42,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.520039,0.00229969,0.515617 kka2_1:1_D216P,kka2_1:1_216,Kka2,kka2_1:1,P00552,,YES,216,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.785,-3.727,2.942,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.520039,0.00229969,0.481343 kka2_1:1_D216S,kka2_1:1_216,Kka2,kka2_1:1,P00552,,YES,216,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.785,-3.233,2.448,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.520039,0.00229969,0.51275 kka2_1:1_D227R,kka2_1:1_227,Kka2,kka2_1:1,P00552,,YES,227,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.758,-3.84,2.082,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.520039,0.00745029,0.487399 kka2_1:1_D238F,kka2_1:1_238,Kka2,kka2_1:1,P00552,,YES,238,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.83,-4.489,1.659,,0.604,H,A,0.75,-0.33,11.329,11.329,92.05,HAB,-2.633,0.520039,0.0113863,0.90615 kka2_1:1_D238I,kka2_1:1_238,Kka2,kka2_1:1,P00552,,YES,238,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.83,-4.106,1.276,,0.604,H,A,0.75,-0.33,11.329,11.329,92.05,HAB,-2.633,0.520039,0.0113863,0.891958 kka2_1:1_D238M,kka2_1:1_238,Kka2,kka2_1:1,P00552,,YES,238,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.83,-3.594,0.764,,0.604,H,A,0.75,-0.33,11.329,11.329,92.05,HAB,-2.633,0.520039,0.0113863,0.915546 kka2_1:1_D238P,kka2_1:1_238,Kka2,kka2_1:1,P00552,,YES,238,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.83,-2.766,-0.064,,0.604,H,A,0.75,-0.33,11.329,11.329,92.05,HAB,-2.633,0.520039,0.0113863,0.877633 kka2_1:1_D238R,kka2_1:1_238,Kka2,kka2_1:1,P00552,,YES,238,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.83,-2.777,-0.053,,0.604,H,A,0.75,-0.33,11.329,11.329,92.05,HAB,-2.633,0.520039,0.0113863,0.944997 kka2_1:1_D23P,kka2_1:1_23,Kka2,kka2_1:1,P00552,,YES,23,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.459,-3.293,0.834,,0.695,E,B,0.75,-0.65,2.655,,65.53,HAH,-1.94033,0.520039,0.007195,0.736068 kka2_1:1_D23W,kka2_1:1_23,Kka2,kka2_1:1,P00552,,YES,23,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.459,-5.599,3.14,,0.695,E,B,0.75,-0.65,2.655,,65.53,HAH,-1.94033,0.520039,0.007195,0.750504 kka2_1:1_D33M,kka2_1:1_33,Kka2,kka2_1:1,P00552,,YES,33,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.186,-4.904,2.718,,0.561,S,A,0.75,3.35,2.568,,71.59,PAH,-1.306,0.520039,0.00633568,0.750613 kka2_1:1_D33P,kka2_1:1_33,Kka2,kka2_1:1,P00552,,YES,33,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.186,-2.939,0.753,,0.561,S,A,0.75,3.35,2.568,,71.59,PAH,-1.306,0.520039,0.00633568,0.716336 kka2_1:1_D33V,kka2_1:1_33,Kka2,kka2_1:1,P00552,,YES,33,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.186,-3.782,1.596,,0.561,S,A,0.75,3.35,2.568,,71.59,PAH,-1.306,0.520039,0.00633568,0.752773 kka2_1:1_D33W,kka2_1:1_33,Kka2,kka2_1:1,P00552,,YES,33,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.186,-5.589,3.403,,0.561,S,A,0.75,3.35,2.568,,71.59,PAH,-1.306,0.520039,0.00633568,0.710967 kka2_1:1_D52M,kka2_1:1_52,Kka2,kka2_1:1,P00552,,YES,52,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.271,-4.777,2.506,,0.22,E,B,0.75,0.8,2.64,,71.59,PAH,-2.38367,0.520039,0.00175694,0.772166 kka2_1:1_D52P,kka2_1:1_52,Kka2,kka2_1:1,P00552,,YES,52,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.271,-3.706,1.435,,0.22,E,B,0.75,0.8,2.64,,71.59,PAH,-2.38367,0.520039,0.00175694,0.656245 kka2_1:1_D52Q,kka2_1:1_52,Kka2,kka2_1:1,P00552,,YES,52,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.271,-3.313,1.042,,0.22,E,B,0.75,0.8,2.64,,71.59,PAH,-2.38367,0.520039,0.00175694,0.819912 kka2_1:1_D5C,kka2_1:1_5,Kka2,kka2_1:1,P00552,,YES,5,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.306,-4.968,3.662,,,,,,,0.895,,71.59,PAO,-1.784,0.520039,0.00222864,1.03194 kka2_1:1_D5I,kka2_1:1_5,Kka2,kka2_1:1,P00552,,YES,5,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.306,-3.821,2.515,,,,,,,0.895,,71.59,PAO,-1.784,0.520039,0.00222864,1.02664 kka2_1:1_D5P,kka2_1:1_5,Kka2,kka2_1:1,P00552,,YES,5,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.306,-3.466,2.16,,,,,,,0.895,,71.59,PAO,-1.784,0.520039,0.00222864,1.07268 kka2_1:1_D5W,kka2_1:1_5,Kka2,kka2_1:1,P00552,,YES,5,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.306,-5.278,3.972,,,,,,,0.895,,71.59,PAO,-1.784,0.520039,0.00222864,1.0236 kka2_1:1_D62C,kka2_1:1_62,Kka2,kka2_1:1,P00552,,YES,62,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.591,-5.15,3.559,,0.262,H,A,0.75,0.08,10.048,10.048,64.39,PAA,-1.77833,0.520039,0.00744243,0.531162 kka2_1:1_D62P,kka2_1:1_62,Kka2,kka2_1:1,P00552,,YES,62,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.591,-3.966,2.375,,0.262,H,A,0.75,0.08,10.048,10.048,64.39,PAA,-1.77833,0.520039,0.00744243,0.499135 kka2_1:1_D62R,kka2_1:1_62,Kka2,kka2_1:1,P00552,,YES,62,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.591,-3.972,2.381,,0.262,H,A,0.75,0.08,10.048,10.048,64.39,PAA,-1.77833,0.520039,0.00744243,0.513939 kka2_1:1_D62S,kka2_1:1_62,Kka2,kka2_1:1,P00552,,YES,62,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.591,-3.356,1.765,,0.262,H,A,0.75,0.08,10.048,10.048,64.39,PAA,-1.77833,0.520039,0.00744243,0.529483 kka2_1:1_D62T,kka2_1:1_62,Kka2,kka2_1:1,P00552,,YES,62,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.591,-3.648,2.057,,0.262,H,A,0.75,0.08,10.048,10.048,64.39,PAA,-1.77833,0.520039,0.00744243,0.522 kka2_1:1_D62V,kka2_1:1_62,Kka2,kka2_1:1,P00552,,YES,62,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.591,-3.746,2.155,,0.262,H,A,0.75,0.08,10.048,10.048,64.39,PAA,-1.77833,0.520039,0.00744243,0.517619 kka2_1:1_D62W,kka2_1:1_62,Kka2,kka2_1:1,P00552,,YES,62,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.591,-5.508,3.917,,0.262,H,A,0.75,0.08,10.048,10.048,64.39,PAA,-1.77833,0.520039,0.00744243,0.455422 kka2_1:1_D82C,kka2_1:1_82,Kka2,kka2_1:1,P00552,,YES,82,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.946,-3.559,1.613,,0.341,E,b,0.75,0.52,11.345,11.345,63.64,HAH,-1.98,0.520039,0.00637516,0.536827 kka2_1:1_D82F,kka2_1:1_82,Kka2,kka2_1:1,P00552,,YES,82,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.946,-4.41,2.464,,0.341,E,b,0.75,0.52,11.345,11.345,63.64,HAH,-1.98,0.520039,0.00637516,0.520986 kka2_1:1_D82M,kka2_1:1_82,Kka2,kka2_1:1,P00552,,YES,82,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.946,-4.849,2.903,,0.341,E,b,0.75,0.52,11.345,11.345,63.64,HAH,-1.98,0.520039,0.00637516,0.564205 kka2_1:1_D82P,kka2_1:1_82,Kka2,kka2_1:1,P00552,,YES,82,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.946,-4.009,2.063,,0.341,E,b,0.75,0.52,11.345,11.345,63.64,HAH,-1.98,0.520039,0.00637516,0.45714 kka2_1:1_D82S,kka2_1:1_82,Kka2,kka2_1:1,P00552,,YES,82,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.946,-2.906,0.96,,0.341,E,b,0.75,0.52,11.345,11.345,63.64,HAH,-1.98,0.520039,0.00637516,0.566725 kka2_1:1_D82W,kka2_1:1_82,Kka2,kka2_1:1,P00552,,YES,82,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.946,-3.611,1.665,,0.341,E,b,0.75,0.52,11.345,11.345,63.64,HAH,-1.98,0.520039,0.00637516,0.510574 kka2_1:1_D90C,kka2_1:1_90,Kka2,kka2_1:1,P00552,,YES,90,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.459,-5.259,2.8,,0.104,E,B,0.75,0.73,6.085,,64.39,BAH,-1.72833,0.520039,0.00583842,0.694145 kka2_1:1_D90L,kka2_1:1_90,Kka2,kka2_1:1,P00552,,YES,90,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.459,-3.657,1.198,,0.104,E,B,0.75,0.73,6.085,,64.39,BAH,-1.72833,0.520039,0.00583842,0.498138 kka2_1:1_D90M,kka2_1:1_90,Kka2,kka2_1:1,P00552,,YES,90,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.459,-4.83,2.371,,0.104,E,B,0.75,0.73,6.085,,64.39,BAH,-1.72833,0.520039,0.00583842,0.57929 kka2_1:1_D90R,kka2_1:1_90,Kka2,kka2_1:1,P00552,,YES,90,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.459,-2.746,0.287,,0.104,E,B,0.75,0.73,6.085,,64.39,BAH,-1.72833,0.520039,0.00583842,0.594058 kka2_1:1_D90S,kka2_1:1_90,Kka2,kka2_1:1,P00552,,YES,90,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.459,-2.612,0.153,,0.104,E,B,0.75,0.73,6.085,,64.39,BAH,-1.72833,0.520039,0.00583842,0.618094 kka2_1:1_D90T,kka2_1:1_90,Kka2,kka2_1:1,P00552,,YES,90,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.459,-3.035,0.576,,0.104,E,B,0.75,0.73,6.085,,64.39,BAH,-1.72833,0.520039,0.00583842,0.56113 kka2_1:1_D90W,kka2_1:1_90,Kka2,kka2_1:1,P00552,,YES,90,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.459,-3.595,1.136,,0.104,E,B,0.75,0.73,6.085,,64.39,BAH,-1.72833,0.520039,0.00583842,0.485798 kka2_1:1_E111C,kka2_1:1_111,Kka2,kka2_1:1,P00552,,YES,111,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.28,-5.229,2.949,,0.155,H,A,1.52,-1.14,15.716,15.716,65.53,HAB,-2.27833,0.520039,0.00746789,0.710835 kka2_1:1_E142I,kka2_1:1_142,Kka2,kka2_1:1,P00552,,YES,142,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.221,-4.073,1.852,,0.471,H,A,1.52,0.85,3.626,,65.53,HAB,-2.08033,0.520039,0.00748883,0.674411 kka2_1:1_E142S,kka2_1:1_142,Kka2,kka2_1:1,P00552,,YES,142,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.221,-2.618,0.397,,0.471,H,A,1.52,0.85,3.626,,65.53,HAB,-2.08033,0.520039,0.00748883,0.76279 kka2_1:1_E149C,kka2_1:1_149,Kka2,kka2_1:1,P00552,,YES,149,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.994,-5.217,3.223,,0.674,H,A,1.04,1.63,3.671,,71.59,HAH,-1.59667,0.520039,0.00803343,0.904253 kka2_1:1_E149F,kka2_1:1_149,Kka2,kka2_1:1,P00552,,YES,149,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.994,-4.387,2.393,,0.674,H,A,1.04,1.63,3.671,,71.59,HAH,-1.59667,0.520039,0.00803343,0.95117 kka2_1:1_E149L,kka2_1:1_149,Kka2,kka2_1:1,P00552,,YES,149,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.994,-2.522,0.528,,0.674,H,A,1.04,1.63,3.671,,71.59,HAH,-1.59667,0.520039,0.00803343,0.844368 kka2_1:1_E149M,kka2_1:1_149,Kka2,kka2_1:1,P00552,,YES,149,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.994,-3.564,1.57,,0.674,H,A,1.04,1.63,3.671,,71.59,HAH,-1.59667,0.520039,0.00803343,0.853182 kka2_1:1_E149P,kka2_1:1_149,Kka2,kka2_1:1,P00552,,YES,149,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.994,-4.051,2.057,,0.674,H,A,1.04,1.63,3.671,,71.59,HAH,-1.59667,0.520039,0.00803343,0.803332 kka2_1:1_E149S,kka2_1:1_149,Kka2,kka2_1:1,P00552,,YES,149,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.994,-2.804,0.81,,0.674,H,A,1.04,1.63,3.671,,71.59,HAH,-1.59667,0.520039,0.00803343,0.847316 kka2_1:1_E160L,kka2_1:1_160,Kka2,kka2_1:1,P00552,,YES,160,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.683,-3.761,2.078,,0.989,G,A,1.04,2.28,0.273,,71.59,AAA,-1.36133,0.520039,0.00935762,0.917483 kka2_1:1_E160M,kka2_1:1_160,Kka2,kka2_1:1,P00552,,YES,160,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.683,-4.919,3.236,,0.989,G,A,1.04,2.28,0.273,,71.59,AAA,-1.36133,0.520039,0.00935762,0.894532 kka2_1:1_E160P,kka2_1:1_160,Kka2,kka2_1:1,P00552,,YES,160,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.683,-2.472,0.789,,0.989,G,A,1.04,2.28,0.273,,71.59,AAA,-1.36133,0.520039,0.00935762,0.77497 kka2_1:1_E160S,kka2_1:1_160,Kka2,kka2_1:1,P00552,,YES,160,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.683,-3.324,1.641,,0.989,G,A,1.04,2.28,0.273,,71.59,AAA,-1.36133,0.520039,0.00935762,0.80643 kka2_1:1_E161S,kka2_1:1_161,Kka2,kka2_1:1,P00552,,YES,161,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.581,-2.422,0.841,,0.829,G,A,1.04,2.24,1.612,,92.05,AAB,-1.861,0.520039,0.00760103,0.751315 kka2_1:1_E169G,kka2_1:1_169,Kka2,kka2_1:1,P00552,,YES,169,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.996,-2.941,0.945,,0.422,H,A,1.04,0.3,7.546,7.546,65.53,HAH,-1.755,0.520039,0.00730086,0.658087 kka2_1:1_E169I,kka2_1:1_169,Kka2,kka2_1:1,P00552,,YES,169,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.996,-4.06,2.064,,0.422,H,A,1.04,0.3,7.546,7.546,65.53,HAH,-1.755,0.520039,0.00730086,0.702206 kka2_1:1_E169R,kka2_1:1_169,Kka2,kka2_1:1,P00552,,YES,169,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.996,-3.888,1.892,,0.422,H,A,1.04,0.3,7.546,7.546,65.53,HAH,-1.755,0.520039,0.00730086,0.708589 kka2_1:1_E17I,kka2_1:1_17,Kka2,kka2_1:1,P00552,,YES,17,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.154,-4.159,2.005,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.520039,0.00688738,0.63946 kka2_1:1_E17N,kka2_1:1_17,Kka2,kka2_1:1,P00552,,YES,17,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.154,-3.14,0.986,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.520039,0.00688738,0.766443 kka2_1:1_E17T,kka2_1:1_17,Kka2,kka2_1:1,P00552,,YES,17,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.154,-2.882,0.728,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.520039,0.00688738,0.774507 kka2_1:1_E17V,kka2_1:1_17,Kka2,kka2_1:1,P00552,,YES,17,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.154,-3.778,1.624,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.520039,0.00688738,0.687369 kka2_1:1_E17W,kka2_1:1_17,Kka2,kka2_1:1,P00552,,YES,17,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.154,-5.592,3.438,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.520039,0.00688738,0.640258 kka2_1:1_E17Y,kka2_1:1_17,Kka2,kka2_1:1,P00552,,YES,17,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.154,-4.407,2.253,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.520039,0.00688738,0.666045 kka2_1:1_E182C,kka2_1:1_182,Kka2,kka2_1:1,P00552,,YES,182,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.516,-3.433,1.917,,0.326,,B,1.52,0.75,14.547,14.547,65.53,OAA,-1.806,0.520039,0.00641548,0.500607 kka2_1:1_E182M,kka2_1:1_182,Kka2,kka2_1:1,P00552,,YES,182,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.516,-4.818,3.302,,0.326,,B,1.52,0.75,14.547,14.547,65.53,OAA,-1.806,0.520039,0.00641548,0.478366 kka2_1:1_E182P,kka2_1:1_182,Kka2,kka2_1:1,P00552,,YES,182,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.516,-3.948,2.432,,0.326,,B,1.52,0.75,14.547,14.547,65.53,OAA,-1.806,0.520039,0.00641548,0.472823 kka2_1:1_E182W,kka2_1:1_182,Kka2,kka2_1:1,P00552,,YES,182,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.516,-5.341,3.825,,0.326,,B,1.52,0.75,14.547,14.547,65.53,OAA,-1.806,0.520039,0.00641548,0.458711 kka2_1:1_E235F,kka2_1:1_235,Kka2,kka2_1:1,P00552,,YES,235,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.955,-4.481,2.526,,0.631,H,A,1.52,0.12,8.521,,65.53,OAH,-2.07267,0.520039,0.0102806,0.818927 kka2_1:1_E235M,kka2_1:1_235,Kka2,kka2_1:1,P00552,,YES,235,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.955,-4.796,2.841,,0.631,H,A,1.52,0.12,8.521,,65.53,OAH,-2.07267,0.520039,0.0102806,0.806463 kka2_1:1_E235S,kka2_1:1_235,Kka2,kka2_1:1,P00552,,YES,235,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.955,-2.915,0.96,,0.631,H,A,1.52,0.12,8.521,,65.53,OAH,-2.07267,0.520039,0.0102806,0.678631 kka2_1:1_E262R,kka2_1:1_262,Kka2,kka2_1:1,P00552,,YES,262,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-0.829,-3.509,2.68,,0.059,G,A,1.04,-0.18,0.837,,42.42,AAH,-0.816,0.520039,0.0191586,0.466087 kka2_1:1_E262S,kka2_1:1_262,Kka2,kka2_1:1,P00552,,YES,262,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-0.829,-3.212,2.383,,0.059,G,A,1.04,-0.18,0.837,,42.42,AAH,-0.816,0.520039,0.0191586,0.52535 kka2_1:1_E3M,kka2_1:1_3,Kka2,kka2_1:1,P00552,,YES,3,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.199,-4.633,2.434,,,,,,,3.435,,92.05,HAP,-2.11567,0.520039,0.00267607,1.014 kka2_1:1_E3S,kka2_1:1_3,Kka2,kka2_1:1,P00552,,YES,3,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.199,-2.253,0.054,,,,,,,3.435,,92.05,HAP,-2.11567,0.520039,0.00267607,0.990447 kka2_1:1_E3T,kka2_1:1_3,Kka2,kka2_1:1,P00552,,YES,3,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.199,-3.32,1.121,,,,,,,3.435,,92.05,HAP,-2.11567,0.520039,0.00267607,1.0002 kka2_1:1_E59A,kka2_1:1_59,Kka2,kka2_1:1,P00552,,YES,59,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-0.952,-3.166,2.214,,0.187,.,L,1.04,0.62,2.648,,50.38,PAH,-1.53,0.520039,0.00280355,0.497636 kka2_1:1_E59C,kka2_1:1_59,Kka2,kka2_1:1,P00552,,YES,59,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-0.952,-5.289,4.337,,0.187,.,L,1.04,0.62,2.648,,50.38,PAH,-1.53,0.520039,0.00280355,0.510667 kka2_1:1_E59H,kka2_1:1_59,Kka2,kka2_1:1,P00552,,YES,59,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-0.952,-4.372,3.42,,0.187,.,L,1.04,0.62,2.648,,50.38,PAH,-1.53,0.520039,0.00280355,0.431195 kka2_1:1_E59M,kka2_1:1_59,Kka2,kka2_1:1,P00552,,YES,59,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-0.952,-4.747,3.795,,0.187,.,L,1.04,0.62,2.648,,50.38,PAH,-1.53,0.520039,0.00280355,0.443424 kka2_1:1_E59N,kka2_1:1_59,Kka2,kka2_1:1,P00552,,YES,59,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-0.952,-3.52,2.568,,0.187,.,L,1.04,0.62,2.648,,50.38,PAH,-1.53,0.520039,0.00280355,0.428444 kka2_1:1_E59S,kka2_1:1_59,Kka2,kka2_1:1,P00552,,YES,59,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-0.952,-3.233,2.281,,0.187,.,L,1.04,0.62,2.648,,50.38,PAH,-1.53,0.520039,0.00280355,0.534909 kka2_1:1_E59T,kka2_1:1_59,Kka2,kka2_1:1,P00552,,YES,59,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-0.952,-2.667,1.715,,0.187,.,L,1.04,0.62,2.648,,50.38,PAH,-1.53,0.520039,0.00280355,0.573762 kka2_1:1_E59W,kka2_1:1_59,Kka2,kka2_1:1,P00552,,YES,59,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-0.952,-5.39,4.438,,0.187,.,L,1.04,0.62,2.648,,50.38,PAH,-1.53,0.520039,0.00280355,0.4125 kka2_1:1_E63C,kka2_1:1_63,Kka2,kka2_1:1,P00552,,YES,63,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-0.762,-5.34,4.578,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.520039,0.00118399,0.465343 kka2_1:1_E63F,kka2_1:1_63,Kka2,kka2_1:1,P00552,,YES,63,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-0.762,-4.32,3.558,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.520039,0.00118399,0.397762 kka2_1:1_E63I,kka2_1:1_63,Kka2,kka2_1:1,P00552,,YES,63,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-0.762,-4.039,3.277,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.520039,0.00118399,0.397831 kka2_1:1_E63M,kka2_1:1_63,Kka2,kka2_1:1,P00552,,YES,63,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-0.762,-4.733,3.971,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.520039,0.00118399,0.431662 kka2_1:1_E63P,kka2_1:1_63,Kka2,kka2_1:1,P00552,,YES,63,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-0.762,-3.683,2.921,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.520039,0.00118399,0.435461 kka2_1:1_E63Q,kka2_1:1_63,Kka2,kka2_1:1,P00552,,YES,63,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-0.762,-3.253,2.491,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.520039,0.00118399,0.441862 kka2_1:1_E63R,kka2_1:1_63,Kka2,kka2_1:1,P00552,,YES,63,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-0.762,-3.511,2.749,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.520039,0.00118399,0.446998 kka2_1:1_E63S,kka2_1:1_63,Kka2,kka2_1:1,P00552,,YES,63,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-0.762,-3.189,2.427,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.520039,0.00118399,0.487435 kka2_1:1_E63T,kka2_1:1_63,Kka2,kka2_1:1,P00552,,YES,63,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-0.762,-3.45,2.688,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.520039,0.00118399,0.455346 kka2_1:1_E63W,kka2_1:1_63,Kka2,kka2_1:1,P00552,,YES,63,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-0.762,-5.351,4.589,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.520039,0.00118399,0.398373 kka2_1:1_E86A,kka2_1:1_86,Kka2,kka2_1:1,P00552,,YES,86,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.86,-2.331,0.471,,0.369,.,B,1.04,1.92,18.506,18.506,63.26,PAH,-1.98067,0.520039,0.00642858,0.697029 kka2_1:1_E86C,kka2_1:1_86,Kka2,kka2_1:1,P00552,,YES,86,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.86,-5.228,3.368,,0.369,.,B,1.04,1.92,18.506,18.506,63.26,PAH,-1.98067,0.520039,0.00642858,0.64938 kka2_1:1_E86I,kka2_1:1_86,Kka2,kka2_1:1,P00552,,YES,86,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.86,-4.165,2.305,,0.369,.,B,1.04,1.92,18.506,18.506,63.26,PAH,-1.98067,0.520039,0.00642858,0.576157 kka2_1:1_E86L,kka2_1:1_86,Kka2,kka2_1:1,P00552,,YES,86,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.86,-3.758,1.898,,0.369,.,B,1.04,1.92,18.506,18.506,63.26,PAH,-1.98067,0.520039,0.00642858,0.611115 kka2_1:1_E86M,kka2_1:1_86,Kka2,kka2_1:1,P00552,,YES,86,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.86,-4.913,3.053,,0.369,.,B,1.04,1.92,18.506,18.506,63.26,PAH,-1.98067,0.520039,0.00642858,0.618685 kka2_1:1_E86N,kka2_1:1_86,Kka2,kka2_1:1,P00552,,YES,86,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.86,-3.654,1.794,,0.369,.,B,1.04,1.92,18.506,18.506,63.26,PAH,-1.98067,0.520039,0.00642858,0.664446 kka2_1:1_E86P,kka2_1:1_86,Kka2,kka2_1:1,P00552,,YES,86,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.86,-3.983,2.123,,0.369,.,B,1.04,1.92,18.506,18.506,63.26,PAH,-1.98067,0.520039,0.00642858,0.564184 kka2_1:1_E86S,kka2_1:1_86,Kka2,kka2_1:1,P00552,,YES,86,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.86,-2.884,1.024,,0.369,.,B,1.04,1.92,18.506,18.506,63.26,PAH,-1.98067,0.520039,0.00642858,0.689682 kka2_1:1_E86T,kka2_1:1_86,Kka2,kka2_1:1,P00552,,YES,86,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.86,-3.681,1.821,,0.369,.,B,1.04,1.92,18.506,18.506,63.26,PAH,-1.98067,0.520039,0.00642858,0.628015 kka2_1:1_E86V,kka2_1:1_86,Kka2,kka2_1:1,P00552,,YES,86,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.86,-3.786,1.926,,0.369,.,B,1.04,1.92,18.506,18.506,63.26,PAH,-1.98067,0.520039,0.00642858,0.617609 kka2_1:1_E86W,kka2_1:1_86,Kka2,kka2_1:1,P00552,,YES,86,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.86,-5.389,3.529,,0.369,.,B,1.04,1.92,18.506,18.506,63.26,PAH,-1.98067,0.520039,0.00642858,0.609533 kka2_1:1_E96C,kka2_1:1_96,Kka2,kka2_1:1,P00552,,YES,96,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.573,-4.752,2.179,,0.476,,B,1.52,-0.65,1.254,,71.59,OAH,-2.143,0.520039,0.00369441,0.661285 kka2_1:1_E96S,kka2_1:1_96,Kka2,kka2_1:1,P00552,,YES,96,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.573,-3.194,0.621,,0.476,,B,1.52,-0.65,1.254,,71.59,OAH,-2.143,0.520039,0.00369441,0.661493 kka2_1:1_F133A,kka2_1:1_133,Kka2,kka2_1:1,P00552,,YES,133,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-0.871,-3.354,2.483,,0.178,.,B,0.58,0.43,1.999,,42.42,OHA,-0.871667,0.520039,0.00182168,0.471435 kka2_1:1_F133E,kka2_1:1_133,Kka2,kka2_1:1,P00552,,YES,133,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-0.871,-3.916,3.045,,0.178,.,B,0.58,0.43,1.999,,42.42,OHA,-0.871667,0.520039,0.00182168,0.426304 kka2_1:1_F133G,kka2_1:1_133,Kka2,kka2_1:1,P00552,,YES,133,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-0.871,-3.635,2.764,,0.178,.,B,0.58,0.43,1.999,,42.42,OHA,-0.871667,0.520039,0.00182168,0.4781 kka2_1:1_F133N,kka2_1:1_133,Kka2,kka2_1:1,P00552,,YES,133,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-0.871,-4.149,3.278,,0.178,.,B,0.58,0.43,1.999,,42.42,OHA,-0.871667,0.520039,0.00182168,0.430492 kka2_1:1_F133P,kka2_1:1_133,Kka2,kka2_1:1,P00552,,YES,133,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-0.871,-4.356,3.485,,0.178,.,B,0.58,0.43,1.999,,42.42,OHA,-0.871667,0.520039,0.00182168,0.45915 kka2_1:1_F133T,kka2_1:1_133,Kka2,kka2_1:1,P00552,,YES,133,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-0.871,-3.698,2.827,,0.178,.,B,0.58,0.43,1.999,,42.42,OHA,-0.871667,0.520039,0.00182168,0.462771 kka2_1:1_F171A,kka2_1:1_171,Kka2,kka2_1:1,P00552,,YES,171,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.326,-3.394,2.068,,0.154,H,A,1.62,-0.1,13.679,13.679,63.64,HHH,-1.45433,0.520039,0.00821426,0.48846 kka2_1:1_F171D,kka2_1:1_171,Kka2,kka2_1:1,P00552,,YES,171,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.326,-4.095,2.769,,0.154,H,A,1.62,-0.1,13.679,13.679,63.64,HHH,-1.45433,0.520039,0.00821426,0.458327 kka2_1:1_F171H,kka2_1:1_171,Kka2,kka2_1:1,P00552,,YES,171,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.326,-3.195,1.869,,0.154,H,A,1.62,-0.1,13.679,13.679,63.64,HHH,-1.45433,0.520039,0.00821426,0.463104 kka2_1:1_F171P,kka2_1:1_171,Kka2,kka2_1:1,P00552,,YES,171,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.326,-4.354,3.028,,0.154,H,A,1.62,-0.1,13.679,13.679,63.64,HHH,-1.45433,0.520039,0.00821426,0.470545 kka2_1:1_F171Q,kka2_1:1_171,Kka2,kka2_1:1,P00552,,YES,171,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.326,-4.325,2.999,,0.154,H,A,1.62,-0.1,13.679,13.679,63.64,HHH,-1.45433,0.520039,0.00821426,0.473496 kka2_1:1_F171R,kka2_1:1_171,Kka2,kka2_1:1,P00552,,YES,171,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.326,-4.175,2.849,,0.154,H,A,1.62,-0.1,13.679,13.679,63.64,HHH,-1.45433,0.520039,0.00821426,0.505695 kka2_1:1_F206R,kka2_1:1_206,Kka2,kka2_1:1,P00552,,YES,206,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.349,-4.172,2.823,,0.006,E,B,0.58,-1.21,0.978,,63.64,OHH,-1.04,0.520039,0.00936868,0.477127 kka2_1:1_F20A,kka2_1:1_20,Kka2,kka2_1:1,P00552,,YES,20,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-3.354,-1.671,-1.683,,0.935,T,B,0.58,-0.41,1.657,,92.05,HHO,-1.992,0.520039,0.00701744,1.03371 kka2_1:1_F20G,kka2_1:1_20,Kka2,kka2_1:1,P00552,,YES,20,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-3.354,-2.338,-1.016,,0.935,T,B,0.58,-0.41,1.657,,92.05,HHO,-1.992,0.520039,0.00701744,1.01076 kka2_1:1_F20I,kka2_1:1_20,Kka2,kka2_1:1,P00552,,YES,20,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-3.354,-3.918,0.564,,0.935,T,B,0.58,-0.41,1.657,,92.05,HHO,-1.992,0.520039,0.00701744,0.869885 kka2_1:1_F20K,kka2_1:1_20,Kka2,kka2_1:1,P00552,,YES,20,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-3.354,-2.992,-0.362,,0.935,T,B,0.58,-0.41,1.657,,92.05,HHO,-1.992,0.520039,0.00701744,0.971975 kka2_1:1_F20N,kka2_1:1_20,Kka2,kka2_1:1,P00552,,YES,20,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-3.354,-3.854,0.5,,0.935,T,B,0.58,-0.41,1.657,,92.05,HHO,-1.992,0.520039,0.00701744,0.903712 kka2_1:1_F20P,kka2_1:1_20,Kka2,kka2_1:1,P00552,,YES,20,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-3.354,-2.906,-0.448,,0.935,T,B,0.58,-0.41,1.657,,92.05,HHO,-1.992,0.520039,0.00701744,0.920721 kka2_1:1_F20R,kka2_1:1_20,Kka2,kka2_1:1,P00552,,YES,20,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-3.354,-2.757,-0.597,,0.935,T,B,0.58,-0.41,1.657,,92.05,HHO,-1.992,0.520039,0.00701744,1.02101 kka2_1:1_F20T,kka2_1:1_20,Kka2,kka2_1:1,P00552,,YES,20,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-3.354,-2.596,-0.758,,0.935,T,B,0.58,-0.41,1.657,,92.05,HHO,-1.992,0.520039,0.00701744,1.02924 kka2_1:1_F20W,kka2_1:1_20,Kka2,kka2_1:1,P00552,,YES,20,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-3.354,-5.49,2.136,,0.935,T,B,0.58,-0.41,1.657,,92.05,HHO,-1.992,0.520039,0.00701744,0.963084 kka2_1:1_F240A,kka2_1:1_240,Kka2,kka2_1:1,P00552,,YES,240,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-0.911,-3.329,2.418,,,H,A,1.62,-1.21,5.798,,50.38,BHH,-1.67267,0.520039,0.00552543,0.447995 kka2_1:1_F240D,kka2_1:1_240,Kka2,kka2_1:1,P00552,,YES,240,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-0.911,-4.011,3.1,,,H,A,1.62,-1.21,5.798,,50.38,BHH,-1.67267,0.520039,0.00552543,0.375991 kka2_1:1_F240K,kka2_1:1_240,Kka2,kka2_1:1,P00552,,YES,240,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-0.911,-3.934,3.023,,,H,A,1.62,-1.21,5.798,,50.38,BHH,-1.67267,0.520039,0.00552543,0.37759 kka2_1:1_F256R,kka2_1:1_256,Kka2,kka2_1:1,P00552,,YES,256,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.49,-3.099,1.609,,,H,A,1.62,-0.78,2.354,,53.03,HHH,-1.423,0.520039,0.0132841,0.520438 kka2_1:1_F263A,kka2_1:1_263,Kka2,kka2_1:1,P00552,,YES,263,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-0.911,-3.329,2.418,,0.006,G,A,0.58,-0.12,2.284,,45.83,AHH,-0.92,0.520039,0.0172454,0.41052 kka2_1:1_F263D,kka2_1:1_263,Kka2,kka2_1:1,P00552,,YES,263,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-0.911,-4.011,3.1,,0.006,G,A,0.58,-0.12,2.284,,45.83,AHH,-0.92,0.520039,0.0172454,0.389456 kka2_1:1_F264R,kka2_1:1_264,Kka2,kka2_1:1,P00552,,YES,264,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.02,-4.192,3.172,,0.296,.,?,0.58,0.02,2.303,,71.59,HHNA,-0.9655,0.520039,,0.493054 kka2_1:1_F37C,kka2_1:1_37,Kka2,kka2_1:1,P00552,,YES,37,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.427,-4.988,3.561,,0.219,E,B,0.58,-0.25,18.64,18.64,64.39,HHB,-1.17733,0.520039,0.00586193,0.53994 kka2_1:1_F37E,kka2_1:1_37,Kka2,kka2_1:1,P00552,,YES,37,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.427,-3.871,2.444,,0.219,E,B,0.58,-0.25,18.64,18.64,64.39,HHB,-1.17733,0.520039,0.00586193,0.435242 kka2_1:1_F37K,kka2_1:1_37,Kka2,kka2_1:1,P00552,,YES,37,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.427,-3.907,2.48,,0.219,E,B,0.58,-0.25,18.64,18.64,64.39,HHB,-1.17733,0.520039,0.00586193,0.439134 kka2_1:1_F37N,kka2_1:1_37,Kka2,kka2_1:1,P00552,,YES,37,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.427,-4.089,2.662,,0.219,E,B,0.58,-0.25,18.64,18.64,64.39,HHB,-1.17733,0.520039,0.00586193,0.430922 kka2_1:1_F37P,kka2_1:1_37,Kka2,kka2_1:1,P00552,,YES,37,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.427,-4.289,2.862,,0.219,E,B,0.58,-0.25,18.64,18.64,64.39,HHB,-1.17733,0.520039,0.00586193,0.460623 kka2_1:1_F37T,kka2_1:1_37,Kka2,kka2_1:1,P00552,,YES,37,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.427,-3.702,2.275,,0.219,E,B,0.58,-0.25,18.64,18.64,64.39,HHB,-1.17733,0.520039,0.00586193,0.495475 kka2_1:1_F48D,kka2_1:1_48,Kka2,kka2_1:1,P00552,,YES,48,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.453,-4.107,2.654,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.520039,0.00475422,0.374658 kka2_1:1_F48G,kka2_1:1_48,Kka2,kka2_1:1,P00552,,YES,48,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.453,-3.796,2.343,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.520039,0.00475422,0.435284 kka2_1:1_F48N,kka2_1:1_48,Kka2,kka2_1:1,P00552,,YES,48,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.453,-4.244,2.791,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.520039,0.00475422,0.362155 kka2_1:1_F48P,kka2_1:1_48,Kka2,kka2_1:1,P00552,,YES,48,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.453,-4.319,2.866,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.520039,0.00475422,0.415301 kka2_1:1_F48T,kka2_1:1_48,Kka2,kka2_1:1,P00552,,YES,48,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.453,-3.684,2.231,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.520039,0.00475422,0.446251 kka2_1:1_F48Y,kka2_1:1_48,Kka2,kka2_1:1,P00552,,YES,48,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.453,-1.946,0.493,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.520039,0.00475422,0.556828 kka2_1:1_G10Y,kka2_1:1_10,Kka2,kka2_1:1,P00552,,YES,10,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.921,-4.276,2.355,,,,,,,1.862,,71.59,HOP,-2.10733,0.520039,0.00289233,0.890854 kka2_1:1_G151H,kka2_1:1_151,Kka2,kka2_1:1,P00552,,YES,151,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.873,-4.645,3.772,,0.678,T,l,0.29,1.36,0.226,,49.62,HOH,-1.11433,0.520039,0.00339918,0.572333 kka2_1:1_G151P,kka2_1:1_151,Kka2,kka2_1:1,P00552,,YES,151,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.873,-3.953,3.08,,0.678,T,l,0.29,1.36,0.226,,49.62,HOH,-1.11433,0.520039,0.00339918,0.577929 kka2_1:1_G164M,kka2_1:1_164,Kka2,kka2_1:1,P00552,,YES,164,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.869,-4.95,4.081,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.520039,0.00442091,0.683154 kka2_1:1_G181M,kka2_1:1_181,Kka2,kka2_1:1,P00552,,YES,181,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-2.698,-4.828,2.13,,0.379,S,B,0.75,0.78,15.356,15.356,71.59,AOA,-2.21,0.520039,0.00728319,0.944701 kka2_1:1_G201T,kka2_1:1_201,Kka2,kka2_1:1,P00552,,YES,201,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.56,-3.028,1.468,,0.149,T,l,0.29,-0.57,16.092,16.092,52.65,POB,-1.92233,0.520039,0.00820117,0.530844 kka2_1:1_G205P,kka2_1:1_205,Kka2,kka2_1:1,P00552,,YES,205,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.596,-3.908,3.312,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.520039,0.00221855,0.442055 kka2_1:1_G21M,kka2_1:1_21,Kka2,kka2_1:1,P00552,,YES,21,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.368,-4.924,3.556,,0.586,T,l,0.29,-0.75,10.291,10.291,71.59,HOH,-2.10167,0.520039,0.00709648,0.785701 kka2_1:1_G21P,kka2_1:1_21,Kka2,kka2_1:1,P00552,,YES,21,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.368,-3.965,2.597,,0.586,T,l,0.29,-0.75,10.291,10.291,71.59,HOH,-2.10167,0.520039,0.00709648,0.732985 kka2_1:1_G21W,kka2_1:1_21,Kka2,kka2_1:1,P00552,,YES,21,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.368,-5.423,4.055,,0.586,T,l,0.29,-0.75,10.291,10.291,71.59,HOH,-2.10167,0.520039,0.00709648,0.729801 kka2_1:1_G21Y,kka2_1:1_21,Kka2,kka2_1:1,P00552,,YES,21,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.368,-4.271,2.903,,0.586,T,l,0.29,-0.75,10.291,10.291,71.59,HOH,-2.10167,0.520039,0.00709648,0.747532 kka2_1:1_G245I,kka2_1:1_245,Kka2,kka2_1:1,P00552,,YES,245,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.812,-4.212,3.4,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.520039,0.00683899,0.469003 kka2_1:1_G30K,kka2_1:1_30,Kka2,kka2_1:1,P00552,,YES,30,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.596,-3.71,3.114,,0.54,S,g,0.29,3.76,,,,HOO,-1.51133,0.520039,0.00159208,0.425462 kka2_1:1_G30M,kka2_1:1_30,Kka2,kka2_1:1,P00552,,YES,30,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.596,-4.958,4.362,,0.54,S,g,0.29,3.76,,,,HOO,-1.51133,0.520039,0.00159208,0.462305 kka2_1:1_G43H,kka2_1:1_43,Kka2,kka2_1:1,P00552,,YES,43,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.587,-4.654,3.067,,0.862,T,l,0.75,-0.67,2.247,,63.26,POB,-2.18533,0.520039,0.0071925,0.692632 kka2_1:1_G43L,kka2_1:1_43,Kka2,kka2_1:1,P00552,,YES,43,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.587,-3.778,2.191,,0.862,T,l,0.75,-0.67,2.247,,63.26,POB,-2.18533,0.520039,0.0071925,0.660197 kka2_1:1_G43N,kka2_1:1_43,Kka2,kka2_1:1,P00552,,YES,43,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.587,-2.611,1.024,,0.862,T,l,0.75,-0.67,2.247,,63.26,POB,-2.18533,0.520039,0.0071925,0.820601 kka2_1:1_G43Q,kka2_1:1_43,Kka2,kka2_1:1,P00552,,YES,43,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.587,-3.198,1.611,,0.862,T,l,0.75,-0.67,2.247,,63.26,POB,-2.18533,0.520039,0.0071925,0.756277 kka2_1:1_G55I,kka2_1:1_55,Kka2,kka2_1:1,P00552,,YES,55,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.625,-3.229,1.604,,0.517,S,b,0.29,1.19,4.035,,63.64,POH,-2.05967,0.520039,0.00667877,0.598231 kka2_1:1_G55Y,kka2_1:1_55,Kka2,kka2_1:1,P00552,,YES,55,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.625,-4.276,2.651,,0.517,S,b,0.29,1.19,4.035,,63.64,POH,-2.05967,0.520039,0.00667877,0.581436 kka2_1:1_G6I,kka2_1:1_6,Kka2,kka2_1:1,P00552,,YES,6,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.685,-3.841,2.156,,,,,,,1.292,,71.59,AOH,-1.639,0.520039,0.00204693,1.04869 kka2_1:1_G88F,kka2_1:1_88,Kka2,kka2_1:1,P00552,,YES,88,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.689,-4.477,2.788,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.520039,0.00685559,0.615773 kka2_1:1_G88H,kka2_1:1_88,Kka2,kka2_1:1,P00552,,YES,88,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.689,-3.199,1.51,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.520039,0.00685559,0.661855 kka2_1:1_G88K,kka2_1:1_88,Kka2,kka2_1:1,P00552,,YES,88,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.689,-3.033,1.344,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.520039,0.00685559,0.68089 kka2_1:1_G88M,kka2_1:1_88,Kka2,kka2_1:1,P00552,,YES,88,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.689,-4.913,3.224,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.520039,0.00685559,0.639882 kka2_1:1_G88P,kka2_1:1_88,Kka2,kka2_1:1,P00552,,YES,88,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.689,-4.037,2.348,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.520039,0.00685559,0.569177 kka2_1:1_G88Q,kka2_1:1_88,Kka2,kka2_1:1,P00552,,YES,88,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.689,-2.821,1.132,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.520039,0.00685559,0.699786 kka2_1:1_G88W,kka2_1:1_88,Kka2,kka2_1:1,P00552,,YES,88,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.689,-5.544,3.855,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.520039,0.00685559,0.616334 kka2_1:1_G99P,kka2_1:1_99,Kka2,kka2_1:1,P00552,,YES,99,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.596,-3.908,3.312,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.520039,0.00186055,0.47729 kka2_1:1_H106C,kka2_1:1_106,Kka2,kka2_1:1,P00552,,YES,106,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-3.13,-5.214,2.084,,1.065,.,a,0.17,-0.95,2.53,,71.59,PBH,-2.10433,0.520039,0.00730778,0.87819 kka2_1:1_H106G,kka2_1:1_106,Kka2,kka2_1:1,P00552,,YES,106,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-3.13,-2.689,-0.441,,1.065,.,a,0.17,-0.95,2.53,,71.59,PBH,-2.10433,0.520039,0.00730778,0.922816 kka2_1:1_H106M,kka2_1:1_106,Kka2,kka2_1:1,P00552,,YES,106,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-3.13,-4.852,1.722,,1.065,.,a,0.17,-0.95,2.53,,71.59,PBH,-2.10433,0.520039,0.00730778,0.697043 kka2_1:1_H106S,kka2_1:1_106,Kka2,kka2_1:1,P00552,,YES,106,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-3.13,-2.484,-0.646,,1.065,.,a,0.17,-0.95,2.53,,71.59,PBH,-2.10433,0.520039,0.00730778,0.943662 kka2_1:1_H106T,kka2_1:1_106,Kka2,kka2_1:1,P00552,,YES,106,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-3.13,-2.51,-0.62,,1.065,.,a,0.17,-0.95,2.53,,71.59,PBH,-2.10433,0.520039,0.00730778,0.945135 kka2_1:1_H124A,kka2_1:1_124,Kka2,kka2_1:1,P00552,,YES,124,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-0.84,-3.331,2.491,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.520039,0.00211296,0.429197 kka2_1:1_H124C,kka2_1:1_124,Kka2,kka2_1:1,P00552,,YES,124,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-0.84,-5.115,4.275,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.520039,0.00211296,0.462053 kka2_1:1_H124E,kka2_1:1_124,Kka2,kka2_1:1,P00552,,YES,124,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-0.84,-3.243,2.403,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.520039,0.00211296,0.453287 kka2_1:1_H124F,kka2_1:1_124,Kka2,kka2_1:1,P00552,,YES,124,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-0.84,-3.87,3.03,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.520039,0.00211296,0.425668 kka2_1:1_H124L,kka2_1:1_124,Kka2,kka2_1:1,P00552,,YES,124,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-0.84,-3.611,2.771,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.520039,0.00211296,0.446499 kka2_1:1_H124M,kka2_1:1_124,Kka2,kka2_1:1,P00552,,YES,124,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-0.84,-4.733,3.893,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.520039,0.00211296,0.449099 kka2_1:1_H124S,kka2_1:1_124,Kka2,kka2_1:1,P00552,,YES,124,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-0.84,-3.414,2.574,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.520039,0.00211296,0.455974 kka2_1:1_H124V,kka2_1:1_124,Kka2,kka2_1:1,P00552,,YES,124,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-0.84,-3.782,2.942,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.520039,0.00211296,0.433872 kka2_1:1_H124W,kka2_1:1_124,Kka2,kka2_1:1,P00552,,YES,124,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-0.84,-5.126,4.286,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.520039,0.00211296,0.407555 kka2_1:1_H139A,kka2_1:1_139,Kka2,kka2_1:1,P00552,,YES,139,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-2.809,-2.449,-0.36,,0.471,H,A,0.17,0.68,1.153,,63.64,BBB,-2.22,0.520039,0.00734779,0.822594 kka2_1:1_H139E,kka2_1:1_139,Kka2,kka2_1:1,P00552,,YES,139,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-2.809,-2.979,0.17,,0.471,H,A,0.17,0.68,1.153,,63.64,BBB,-2.22,0.520039,0.00734779,0.728024 kka2_1:1_H139M,kka2_1:1_139,Kka2,kka2_1:1,P00552,,YES,139,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-2.809,-3.708,0.899,,0.471,H,A,0.17,0.68,1.153,,63.64,BBB,-2.22,0.520039,0.00734779,0.697846 kka2_1:1_H139V,kka2_1:1_139,Kka2,kka2_1:1,P00552,,YES,139,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-2.809,-2.837,0.028,,0.471,H,A,0.17,0.68,1.153,,63.64,BBB,-2.22,0.520039,0.00734779,0.75718 kka2_1:1_H139W,kka2_1:1_139,Kka2,kka2_1:1,P00552,,YES,139,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-2.809,-5.517,2.708,,0.471,H,A,0.17,0.68,1.153,,63.64,BBB,-2.22,0.520039,0.00734779,0.834516 kka2_1:1_H162A,kka2_1:1_162,Kka2,kka2_1:1,P00552,,YES,162,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-2.319,-3.316,0.997,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.520039,0.00616145,0.464783 kka2_1:1_H162G,kka2_1:1_162,Kka2,kka2_1:1,P00552,,YES,162,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-2.319,-3.406,1.087,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.520039,0.00616145,0.450186 kka2_1:1_H162S,kka2_1:1_162,Kka2,kka2_1:1,P00552,,YES,162,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-2.319,-3.471,1.152,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.520039,0.00616145,0.482895 kka2_1:1_H162T,kka2_1:1_162,Kka2,kka2_1:1,P00552,,YES,162,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-2.319,-3.571,1.252,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.520039,0.00616145,0.462242 kka2_1:1_H162W,kka2_1:1_162,Kka2,kka2_1:1,P00552,,YES,162,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-2.319,-2.828,0.509,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.520039,0.00616145,0.551968 kka2_1:1_H8M,kka2_1:1_8,Kka2,kka2_1:1,P00552,,YES,8,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-2.759,-4.438,1.679,,,,,,,16.971,16.971,71.59,HBH,-2.25467,0.520039,0.00256422,0.963095 kka2_1:1_H8P,kka2_1:1_8,Kka2,kka2_1:1,P00552,,YES,8,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-2.759,-3.809,1.05,,,,,,,16.971,16.971,71.59,HBH,-2.25467,0.520039,0.00256422,0.888232 kka2_1:1_H8S,kka2_1:1_8,Kka2,kka2_1:1,P00552,,YES,8,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-2.759,-2.388,-0.371,,,,,,,16.971,16.971,71.59,HBH,-2.25467,0.520039,0.00256422,1.04642 kka2_1:1_I141A,kka2_1:1_141,Kka2,kka2_1:1,P00552,,YES,141,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.495,-3.207,1.712,,0.068,H,A,0.48,-0.01,7.546,7.546,92.05,BHA,-1.689,0.520039,0.00744745,0.461723 kka2_1:1_I141G,kka2_1:1_141,Kka2,kka2_1:1,P00552,,YES,141,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.495,-3.916,2.421,,0.068,H,A,0.48,-0.01,7.546,7.546,92.05,BHA,-1.689,0.520039,0.00744745,0.493616 kka2_1:1_I141P,kka2_1:1_141,Kka2,kka2_1:1,P00552,,YES,141,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.495,-4.213,2.718,,0.068,H,A,0.48,-0.01,7.546,7.546,92.05,BHA,-1.689,0.520039,0.00744745,0.477572 kka2_1:1_I141R,kka2_1:1_141,Kka2,kka2_1:1,P00552,,YES,141,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.495,-4.204,2.709,,0.068,H,A,0.48,-0.01,7.546,7.546,92.05,BHA,-1.689,0.520039,0.00744745,0.525093 kka2_1:1_I141W,kka2_1:1_141,Kka2,kka2_1:1,P00552,,YES,141,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.495,-5.368,3.873,,0.068,H,A,0.48,-0.01,7.546,7.546,92.05,BHA,-1.689,0.520039,0.00744745,0.458291 kka2_1:1_I221A,kka2_1:1_221,Kka2,kka2_1:1,P00552,,YES,221,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.739,-3.216,1.477,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.520039,0.00945908,0.473475 kka2_1:1_I246D,kka2_1:1_246,Kka2,kka2_1:1,P00552,,YES,246,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-2.008,-3.218,1.21,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.520039,0.0139479,0.572271 kka2_1:1_I246F,kka2_1:1_246,Kka2,kka2_1:1,P00552,,YES,246,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-2.008,-3.274,1.266,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.520039,0.0139479,0.581035 kka2_1:1_I246G,kka2_1:1_246,Kka2,kka2_1:1,P00552,,YES,246,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-2.008,-2.463,0.455,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.520039,0.0139479,0.720992 kka2_1:1_I246Q,kka2_1:1_246,Kka2,kka2_1:1,P00552,,YES,246,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-2.008,-4.292,2.284,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.520039,0.0139479,0.689669 kka2_1:1_I246W,kka2_1:1_246,Kka2,kka2_1:1,P00552,,YES,246,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-2.008,-5.452,3.444,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.520039,0.0139479,0.649654 kka2_1:1_I254R,kka2_1:1_254,Kka2,kka2_1:1,P00552,,YES,254,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.933,-3.154,1.221,,0.135,H,A,1.52,-0.6,1.859,,71.59,BHH,-1.668,0.520039,0.0132375,0.518805 kka2_1:1_I29C,kka2_1:1_29,Kka2,kka2_1:1,P00552,,YES,29,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.692,-4.988,3.296,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.520039,0.00619521,0.706131 kka2_1:1_I29E,kka2_1:1_29,Kka2,kka2_1:1,P00552,,YES,29,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.692,-2.793,1.101,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.520039,0.00619521,0.784862 kka2_1:1_I29G,kka2_1:1_29,Kka2,kka2_1:1,P00552,,YES,29,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.692,-2.967,1.275,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.520039,0.00619521,0.789246 kka2_1:1_I29P,kka2_1:1_29,Kka2,kka2_1:1,P00552,,YES,29,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.692,-4.154,2.462,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.520039,0.00619521,0.629387 kka2_1:1_I29W,kka2_1:1_29,Kka2,kka2_1:1,P00552,,YES,29,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.692,-5.447,3.755,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.520039,0.00619521,0.660386 kka2_1:1_I2A,kka2_1:1_2,Kka2,kka2_1:1,P00552,,YES,2,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.787,-2.783,0.996,,,,,,,2.329,,71.59,HHA,-1.92433,0.520039,0.00246644,1.02297 kka2_1:1_K112A,kka2_1:1_112,Kka2,kka2_1:1,P00552,,YES,112,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-2.491,-2.624,0.133,,0.076,H,A,2.34,-1.37,23.433,23.433,56.06,ABH,-2.00133,0.520039,0.00645389,0.573148 kka2_1:1_K112G,kka2_1:1_112,Kka2,kka2_1:1,P00552,,YES,112,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-2.491,-3.699,1.208,,0.076,H,A,2.34,-1.37,23.433,23.433,56.06,ABH,-2.00133,0.520039,0.00645389,0.4705 kka2_1:1_K112V,kka2_1:1_112,Kka2,kka2_1:1,P00552,,YES,112,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-2.491,-2.276,-0.215,,0.076,H,A,2.34,-1.37,23.433,23.433,56.06,ABH,-2.00133,0.520039,0.00645389,0.626651 kka2_1:1_K138A,kka2_1:1_138,Kka2,kka2_1:1,P00552,,YES,138,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-2.5,-2.407,-0.093,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.520039,0.00628542,0.81766 kka2_1:1_K138P,kka2_1:1_138,Kka2,kka2_1:1,P00552,,YES,138,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-2.5,-3.19,0.69,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.520039,0.00628542,0.710223 kka2_1:1_K175F,kka2_1:1_175,Kka2,kka2_1:1,P00552,,YES,175,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-2.897,-4.186,1.289,,0.579,H,A,1.3,0.51,9.33,9.33,71.59,HBH,-1.82333,0.520039,0.00693093,0.784314 kka2_1:1_K175L,kka2_1:1_175,Kka2,kka2_1:1,P00552,,YES,175,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-2.897,-1.898,-0.999,,0.579,H,A,1.3,0.51,9.33,9.33,71.59,HBH,-1.82333,0.520039,0.00693093,0.953599 kka2_1:1_K175W,kka2_1:1_175,Kka2,kka2_1:1,P00552,,YES,175,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-2.897,-5.429,2.532,,0.579,H,A,1.3,0.51,9.33,9.33,71.59,HBH,-1.82333,0.520039,0.00693093,0.836153 kka2_1:1_K50C,kka2_1:1_50,Kka2,kka2_1:1,P00552,,YES,50,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-0.833,-5.139,4.306,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.520039,0.00138626,0.502108 kka2_1:1_K50F,kka2_1:1_50,Kka2,kka2_1:1,P00552,,YES,50,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-0.833,-4.344,3.511,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.520039,0.00138626,0.420216 kka2_1:1_K50G,kka2_1:1_50,Kka2,kka2_1:1,P00552,,YES,50,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-0.833,-3.41,2.577,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.520039,0.00138626,0.501341 kka2_1:1_K50M,kka2_1:1_50,Kka2,kka2_1:1,P00552,,YES,50,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-0.833,-4.531,3.698,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.520039,0.00138626,0.432874 kka2_1:1_K50P,kka2_1:1_50,Kka2,kka2_1:1,P00552,,YES,50,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-0.833,-3.727,2.894,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.520039,0.00138626,0.462259 kka2_1:1_K50W,kka2_1:1_50,Kka2,kka2_1:1,P00552,,YES,50,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-0.833,-5.374,4.541,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.520039,0.00138626,0.393929 kka2_1:1_K50Y,kka2_1:1_50,Kka2,kka2_1:1,P00552,,YES,50,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-0.833,-4.214,3.381,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.520039,0.00138626,0.435214 kka2_1:1_L102A,kka2_1:1_102,Kka2,kka2_1:1,P00552,,YES,102,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.804,-3.129,2.325,,,T,A,0.55,-1.17,4.258,,42.42,AHH,-1.398,0.520039,0.00201332,0.442002 kka2_1:1_L102G,kka2_1:1_102,Kka2,kka2_1:1,P00552,,YES,102,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.804,-3.835,3.031,,,T,A,0.55,-1.17,4.258,,42.42,AHH,-1.398,0.520039,0.00201332,0.41504 kka2_1:1_L102K,kka2_1:1_102,Kka2,kka2_1:1,P00552,,YES,102,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.804,-3.708,2.904,,,T,A,0.55,-1.17,4.258,,42.42,AHH,-1.398,0.520039,0.00201332,0.377372 kka2_1:1_L102N,kka2_1:1_102,Kka2,kka2_1:1,P00552,,YES,102,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.804,-4.149,3.345,,,T,A,0.55,-1.17,4.258,,42.42,AHH,-1.398,0.520039,0.00201332,0.37523 kka2_1:1_L102T,kka2_1:1_102,Kka2,kka2_1:1,P00552,,YES,102,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.804,-3.473,2.669,,,T,A,0.55,-1.17,4.258,,42.42,AHH,-1.398,0.520039,0.00201332,0.437328 kka2_1:1_L102W,kka2_1:1_102,Kka2,kka2_1:1,P00552,,YES,102,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.804,-5.124,4.32,,,T,A,0.55,-1.17,4.258,,42.42,AHH,-1.398,0.520039,0.00201332,0.353546 kka2_1:1_L103E,kka2_1:1_103,Kka2,kka2_1:1,P00552,,YES,103,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-2.362,-2.689,0.327,,0.394,T,A,0.55,-0.99,4.121,,63.64,HHP,-1.534,0.520039,0.00574792,0.615137 kka2_1:1_L103S,kka2_1:1_103,Kka2,kka2_1:1,P00552,,YES,103,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-2.362,-2.565,0.203,,0.394,T,A,0.55,-0.99,4.121,,63.64,HHP,-1.534,0.520039,0.00574792,0.647851 kka2_1:1_L103Y,kka2_1:1_103,Kka2,kka2_1:1,P00552,,YES,103,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-2.362,-4.297,1.935,,0.394,T,A,0.55,-0.99,4.121,,63.64,HHP,-1.534,0.520039,0.00574792,0.634889 kka2_1:1_L107G,kka2_1:1_107,Kka2,kka2_1:1,P00552,,YES,107,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.238,-3.822,2.584,,0.197,.,B,0.55,-1.1,3.542,,71.59,BHH,-2.143,0.520039,0.00561937,0.459097 kka2_1:1_L123C,kka2_1:1_123,Kka2,kka2_1:1,P00552,,YES,123,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.888,-4.72,3.832,,0.007,H,A,0.55,-0.4,1.447,,48.86,BHB,-1.301,0.520039,0.00325188,0.511022 kka2_1:1_L123D,kka2_1:1_123,Kka2,kka2_1:1,P00552,,YES,123,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.888,-4.173,3.285,,0.007,H,A,0.55,-0.4,1.447,,48.86,BHB,-1.301,0.520039,0.00325188,0.393029 kka2_1:1_L123E,kka2_1:1_123,Kka2,kka2_1:1,P00552,,YES,123,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.888,-3.94,3.052,,0.007,H,A,0.55,-0.4,1.447,,48.86,BHB,-1.301,0.520039,0.00325188,0.382866 kka2_1:1_L123F,kka2_1:1_123,Kka2,kka2_1:1,P00552,,YES,123,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.888,-3.7,2.812,,0.007,H,A,0.55,-0.4,1.447,,48.86,BHB,-1.301,0.520039,0.00325188,0.384518 kka2_1:1_L123G,kka2_1:1_123,Kka2,kka2_1:1,P00552,,YES,123,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.888,-3.859,2.971,,0.007,H,A,0.55,-0.4,1.447,,48.86,BHB,-1.301,0.520039,0.00325188,0.44172 kka2_1:1_L123K,kka2_1:1_123,Kka2,kka2_1:1,P00552,,YES,123,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.888,-3.75,2.862,,0.007,H,A,0.55,-0.4,1.447,,48.86,BHB,-1.301,0.520039,0.00325188,0.385579 kka2_1:1_L123N,kka2_1:1_123,Kka2,kka2_1:1,P00552,,YES,123,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.888,-4.173,3.285,,0.007,H,A,0.55,-0.4,1.447,,48.86,BHB,-1.301,0.520039,0.00325188,0.380922 kka2_1:1_L123T,kka2_1:1_123,Kka2,kka2_1:1,P00552,,YES,123,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.888,-3.505,2.617,,0.007,H,A,0.55,-0.4,1.447,,48.86,BHB,-1.301,0.520039,0.00325188,0.454106 kka2_1:1_L123Y,kka2_1:1_123,Kka2,kka2_1:1,P00552,,YES,123,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.888,-4.021,3.133,,0.007,H,A,0.55,-0.4,1.447,,48.86,BHB,-1.301,0.520039,0.00325188,0.387363 kka2_1:1_L126C,kka2_1:1_126,Kka2,kka2_1:1,P00552,,YES,126,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.246,-4.83,3.584,,0.285,S,B,0.55,0.12,0.302,,51.89,PHA,-1.744,0.520039,0.0066485,0.563977 kka2_1:1_L126D,kka2_1:1_126,Kka2,kka2_1:1,P00552,,YES,126,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.246,-4.074,2.828,,0.285,S,B,0.55,0.12,0.302,,51.89,PHA,-1.744,0.520039,0.0066485,0.433283 kka2_1:1_L126K,kka2_1:1_126,Kka2,kka2_1:1,P00552,,YES,126,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.246,-3.81,2.564,,0.285,S,B,0.55,0.12,0.302,,51.89,PHA,-1.744,0.520039,0.0066485,0.440795 kka2_1:1_L126N,kka2_1:1_126,Kka2,kka2_1:1,P00552,,YES,126,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.246,-4.157,2.911,,0.285,S,B,0.55,0.12,0.302,,51.89,PHA,-1.744,0.520039,0.0066485,0.433635 kka2_1:1_L126T,kka2_1:1_126,Kka2,kka2_1:1,P00552,,YES,126,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.246,-2.585,1.339,,0.285,S,B,0.55,0.12,0.302,,51.89,PHA,-1.744,0.520039,0.0066485,0.529333 kka2_1:1_L126Y,kka2_1:1_126,Kka2,kka2_1:1,P00552,,YES,126,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.246,-4.126,2.88,,0.285,S,B,0.55,0.12,0.302,,51.89,PHA,-1.744,0.520039,0.0066485,0.459757 kka2_1:1_L152A,kka2_1:1_152,Kka2,kka2_1:1,P00552,,YES,152,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.521,-2.279,0.758,,0.547,.,A,0.55,1.36,1.589,,63.64,OHH,-1.162,0.520039,0.00674868,0.683715 kka2_1:1_L152C,kka2_1:1_152,Kka2,kka2_1:1,P00552,,YES,152,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.521,-4.941,3.42,,0.547,.,A,0.55,1.36,1.589,,63.64,OHH,-1.162,0.520039,0.00674868,0.666266 kka2_1:1_L152G,kka2_1:1_152,Kka2,kka2_1:1,P00552,,YES,152,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.521,-3.713,2.192,,0.547,.,A,0.55,1.36,1.589,,63.64,OHH,-1.162,0.520039,0.00674868,0.650217 kka2_1:1_L152S,kka2_1:1_152,Kka2,kka2_1:1,P00552,,YES,152,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.521,-3.591,2.07,,0.547,.,A,0.55,1.36,1.589,,63.64,OHH,-1.162,0.520039,0.00674868,0.671401 kka2_1:1_L152Y,kka2_1:1_152,Kka2,kka2_1:1,P00552,,YES,152,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.521,-4.238,2.717,,0.547,.,A,0.55,1.36,1.589,,63.64,OHH,-1.162,0.520039,0.00674868,0.578407 kka2_1:1_L158C,kka2_1:1_158,Kka2,kka2_1:1,P00552,,YES,158,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.947,-4.909,2.962,,0.095,.,B,0.55,0.77,7.588,,63.64,AHA,-1.25333,0.520039,0.00529068,0.66256 kka2_1:1_L158S,kka2_1:1_158,Kka2,kka2_1:1,P00552,,YES,158,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.947,-3.691,1.744,,0.095,.,B,0.55,0.77,7.588,,63.64,AHA,-1.25333,0.520039,0.00529068,0.505237 kka2_1:1_L158T,kka2_1:1_158,Kka2,kka2_1:1,P00552,,YES,158,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.947,-3.635,1.688,,0.095,.,B,0.55,0.77,7.588,,63.64,AHA,-1.25333,0.520039,0.00529068,0.504144 kka2_1:1_L165W,kka2_1:1_165,Kka2,kka2_1:1,P00552,,YES,165,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-2.453,-3.283,0.83,,0.299,,B,1.59,1.12,2.47,,64.39,OHH,-1.90967,0.520039,0.00801161,0.761948 kka2_1:1_L170D,kka2_1:1_170,Kka2,kka2_1:1,P00552,,YES,170,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.28,-4.131,2.851,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.520039,0.00730791,0.444709 kka2_1:1_L174W,kka2_1:1_174,Kka2,kka2_1:1,P00552,,YES,174,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.952,-5.22,4.268,,,H,A,0.55,-0.31,13.276,13.276,51.89,BHB,-2.08533,0.520039,0.00438501,0.427628 kka2_1:1_L19A,kka2_1:1_19,Kka2,kka2_1:1,P00552,,YES,19,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.254,-3.301,2.047,,0.08,T,A,0.55,-0.26,17.165,17.165,65.53,BHH,-2.221,0.520039,0.00620703,0.464565 kka2_1:1_L19D,kka2_1:1_19,Kka2,kka2_1:1,P00552,,YES,19,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.254,-4.151,2.897,,0.08,T,A,0.55,-0.26,17.165,17.165,65.53,BHH,-2.221,0.520039,0.00620703,0.460621 kka2_1:1_L19E,kka2_1:1_19,Kka2,kka2_1:1,P00552,,YES,19,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.254,-3.966,2.712,,0.08,T,A,0.55,-0.26,17.165,17.165,65.53,BHH,-2.221,0.520039,0.00620703,0.457289 kka2_1:1_L19Y,kka2_1:1_19,Kka2,kka2_1:1,P00552,,YES,19,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.254,-2.672,1.418,,0.08,T,A,0.55,-0.26,17.165,17.165,65.53,BHH,-2.221,0.520039,0.00620703,0.646274 kka2_1:1_L212G,kka2_1:1_212,Kka2,kka2_1:1,P00552,,YES,212,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.904,-3.697,2.793,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.520039,0.0031426,0.479837 kka2_1:1_L223E,kka2_1:1_223,Kka2,kka2_1:1,P00552,,YES,223,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.861,-3.963,3.102,,,H,A,0.55,-1.24,1.268,,50,HHH,-0.854333,0.520039,0.00253574,0.373812 kka2_1:1_L241A,kka2_1:1_241,Kka2,kka2_1:1,P00552,,YES,241,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.158,-3.226,2.068,,0.08,H,A,0.55,-0.82,1.685,,63.26,HHH,-1.58533,0.520039,0.0117299,0.451217 kka2_1:1_L241S,kka2_1:1_241,Kka2,kka2_1:1,P00552,,YES,241,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.158,-3.689,2.531,,0.08,H,A,0.55,-0.82,1.685,,63.26,HHH,-1.58533,0.520039,0.0117299,0.452969 kka2_1:1_L243D,kka2_1:1_243,Kka2,kka2_1:1,P00552,,YES,243,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-2.651,-3.837,1.186,,0.277,H,A,0.55,-0.67,4.334,,92.05,HHH,-2.03767,0.520039,0.00884927,0.544702 kka2_1:1_L243S,kka2_1:1_243,Kka2,kka2_1:1,P00552,,YES,243,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-2.651,-2.842,0.191,,0.277,H,A,0.55,-0.67,4.334,,92.05,HHH,-2.03767,0.520039,0.00884927,0.722762 kka2_1:1_L260Y,kka2_1:1_260,Kka2,kka2_1:1,P00552,,YES,260,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.741,-3.966,3.225,,0.022,H,A,0.55,-0.52,,,,HHA,-0.845667,0.520039,0.0233782,0.365354 kka2_1:1_L39C,kka2_1:1_39,Kka2,kka2_1:1,P00552,,YES,39,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.223,-4.817,3.594,,,E,B,0.55,-1.21,0.925,,71.59,BHP,-1.69167,0.520039,0.00493618,0.556049 kka2_1:1_L39F,kka2_1:1_39,Kka2,kka2_1:1,P00552,,YES,39,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.223,-2.955,1.732,,,E,B,0.55,-1.21,0.925,,71.59,BHP,-1.69167,0.520039,0.00493618,0.502613 kka2_1:1_L39S,kka2_1:1_39,Kka2,kka2_1:1,P00552,,YES,39,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.223,-3.678,2.455,,,E,B,0.55,-1.21,0.925,,71.59,BHP,-1.69167,0.520039,0.00493618,0.479648 kka2_1:1_L39T,kka2_1:1_39,Kka2,kka2_1:1,P00552,,YES,39,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.223,-3.551,2.328,,,E,B,0.55,-1.21,0.925,,71.59,BHP,-1.69167,0.520039,0.00493618,0.519808 kka2_1:1_L39Y,kka2_1:1_39,Kka2,kka2_1:1,P00552,,YES,39,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.223,-4.042,2.819,,,E,B,0.55,-1.21,0.925,,71.59,BHP,-1.69167,0.520039,0.00493618,0.434854 kka2_1:1_L53A,kka2_1:1_53,Kka2,kka2_1:1,P00552,,YES,53,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-2.681,-2.486,-0.195,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.520039,0.00671168,0.875255 kka2_1:1_L53G,kka2_1:1_53,Kka2,kka2_1:1,P00552,,YES,53,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-2.681,-3.649,0.968,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.520039,0.00671168,0.775064 kka2_1:1_L53N,kka2_1:1_53,Kka2,kka2_1:1,P00552,,YES,53,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-2.681,-3.274,0.593,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.520039,0.00671168,0.809064 kka2_1:1_L53T,kka2_1:1_53,Kka2,kka2_1:1,P00552,,YES,53,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-2.681,-3.105,0.424,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.520039,0.00671168,0.778139 kka2_1:1_L53W,kka2_1:1_53,Kka2,kka2_1:1,P00552,,YES,53,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-2.681,-5.633,2.952,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.520039,0.00671168,0.86581 kka2_1:1_L57C,kka2_1:1_57,Kka2,kka2_1:1,P00552,,YES,57,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.898,-5.037,3.139,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.520039,0.00723769,0.597867 kka2_1:1_L57F,kka2_1:1_57,Kka2,kka2_1:1,P00552,,YES,57,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.898,-1.677,-0.221,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.520039,0.00723769,0.76753 kka2_1:1_L57G,kka2_1:1_57,Kka2,kka2_1:1,P00552,,YES,57,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.898,-3.786,1.888,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.520039,0.00723769,0.485808 kka2_1:1_L57S,kka2_1:1_57,Kka2,kka2_1:1,P00552,,YES,57,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.898,-3.77,1.872,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.520039,0.00723769,0.491058 kka2_1:1_L57Y,kka2_1:1_57,Kka2,kka2_1:1,P00552,,YES,57,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.898,-2.955,1.057,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.520039,0.00723769,0.57179 kka2_1:1_L60E,kka2_1:1_60,Kka2,kka2_1:1,P00552,,YES,60,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.997,-3.964,2.967,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.520039,0.00262176,0.455153 kka2_1:1_L60F,kka2_1:1_60,Kka2,kka2_1:1,P00552,,YES,60,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.997,-2.839,1.842,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.520039,0.00262176,0.518066 kka2_1:1_L60N,kka2_1:1_60,Kka2,kka2_1:1,P00552,,YES,60,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.997,-4.225,3.228,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.520039,0.00262176,0.434179 kka2_1:1_L60T,kka2_1:1_60,Kka2,kka2_1:1,P00552,,YES,60,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.997,-3.529,2.532,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.520039,0.00262176,0.48634 kka2_1:1_L60W,kka2_1:1_60,Kka2,kka2_1:1,P00552,,YES,60,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.997,-5.166,4.169,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.520039,0.00262176,0.412464 kka2_1:1_L60Y,kka2_1:1_60,Kka2,kka2_1:1,P00552,,YES,60,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.997,-3.955,2.958,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.520039,0.00262176,0.462418 kka2_1:1_L67C,kka2_1:1_67,Kka2,kka2_1:1,P00552,,YES,67,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.741,-4.665,3.924,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.520039,0.00102787,0.444752 kka2_1:1_L67E,kka2_1:1_67,Kka2,kka2_1:1,P00552,,YES,67,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.741,-3.918,3.177,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.520039,0.00102787,0.359357 kka2_1:1_L67G,kka2_1:1_67,Kka2,kka2_1:1,P00552,,YES,67,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.741,-3.836,3.095,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.520039,0.00102787,0.404758 kka2_1:1_L67H,kka2_1:1_67,Kka2,kka2_1:1,P00552,,YES,67,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.741,-4.933,4.192,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.520039,0.00102787,0.386242 kka2_1:1_L67I,kka2_1:1_67,Kka2,kka2_1:1,P00552,,YES,67,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.741,-2.914,2.173,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.520039,0.00102787,0.445205 kka2_1:1_L67K,kka2_1:1_67,Kka2,kka2_1:1,P00552,,YES,67,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.741,-3.71,2.969,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.520039,0.00102787,0.361813 kka2_1:1_L67N,kka2_1:1_67,Kka2,kka2_1:1,P00552,,YES,67,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.741,-4.151,3.41,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.520039,0.00102787,0.365438 kka2_1:1_L67Q,kka2_1:1_67,Kka2,kka2_1:1,P00552,,YES,67,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.741,-4.153,3.412,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.520039,0.00102787,0.371506 kka2_1:1_L67T,kka2_1:1_67,Kka2,kka2_1:1,P00552,,YES,67,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.741,-3.45,2.709,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.520039,0.00102787,0.41752 kka2_1:1_L70D,kka2_1:1_70,Kka2,kka2_1:1,P00552,,YES,70,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.017,-4.187,3.17,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.520039,0.00411884,0.404881 kka2_1:1_L70E,kka2_1:1_70,Kka2,kka2_1:1,P00552,,YES,70,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.017,-3.949,2.932,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.520039,0.00411884,0.395813 kka2_1:1_L70G,kka2_1:1_70,Kka2,kka2_1:1,P00552,,YES,70,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.017,-3.868,2.851,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.520039,0.00411884,0.444047 kka2_1:1_L70H,kka2_1:1_70,Kka2,kka2_1:1,P00552,,YES,70,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.017,-4.982,3.965,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.520039,0.00411884,0.415054 kka2_1:1_L70N,kka2_1:1_70,Kka2,kka2_1:1,P00552,,YES,70,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.017,-4.199,3.182,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.520039,0.00411884,0.394994 kka2_1:1_L70S,kka2_1:1_70,Kka2,kka2_1:1,P00552,,YES,70,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.017,-3.687,2.67,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.520039,0.00411884,0.445366 kka2_1:1_L70T,kka2_1:1_70,Kka2,kka2_1:1,P00552,,YES,70,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.017,-3.534,2.517,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.520039,0.00411884,0.453943 kka2_1:1_L70W,kka2_1:1_70,Kka2,kka2_1:1,P00552,,YES,70,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.017,-5.201,4.184,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.520039,0.00411884,0.390925 kka2_1:1_L70Y,kka2_1:1_70,Kka2,kka2_1:1,P00552,,YES,70,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.017,-4.068,3.051,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.520039,0.00411884,0.401877 kka2_1:1_L7E,kka2_1:1_7,Kka2,kka2_1:1,P00552,,YES,7,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.926,-3.32,1.394,,,,,,,18.934,18.934,71.59,OHB,-2.12333,0.520039,0.00269456,0.946902 kka2_1:1_L7G,kka2_1:1_7,Kka2,kka2_1:1,P00552,,YES,7,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.926,-2.13,0.204,,,,,,,18.934,18.934,71.59,OHB,-2.12333,0.520039,0.00269456,0.966668 kka2_1:1_L7T,kka2_1:1_7,Kka2,kka2_1:1,P00552,,YES,7,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.926,-3.425,1.499,,,,,,,18.934,18.934,71.59,OHB,-2.12333,0.520039,0.00269456,0.963446 kka2_1:1_L81A,kka2_1:1_81,Kka2,kka2_1:1,P00552,,YES,81,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.427,-3.213,1.786,,0.46,E,A,0.55,-0.14,0.374,,63.64,HHA,-1.50567,0.520039,0.00805839,0.544174 kka2_1:1_L81C,kka2_1:1_81,Kka2,kka2_1:1,P00552,,YES,81,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.427,-4.845,3.418,,0.46,E,A,0.55,-0.14,0.374,,63.64,HHA,-1.50567,0.520039,0.00805839,0.70398 kka2_1:1_L81D,kka2_1:1_81,Kka2,kka2_1:1,P00552,,YES,81,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.427,-4.125,2.698,,0.46,E,A,0.55,-0.14,0.374,,63.64,HHA,-1.50567,0.520039,0.00805839,0.621891 kka2_1:1_L81E,kka2_1:1_81,Kka2,kka2_1:1,P00552,,YES,81,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.427,-3.901,2.474,,0.46,E,A,0.55,-0.14,0.374,,63.64,HHA,-1.50567,0.520039,0.00805839,0.617116 kka2_1:1_L81F,kka2_1:1_81,Kka2,kka2_1:1,P00552,,YES,81,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.427,-3.878,2.451,,0.46,E,A,0.55,-0.14,0.374,,63.64,HHA,-1.50567,0.520039,0.00805839,0.623715 kka2_1:1_L81G,kka2_1:1_81,Kka2,kka2_1:1,P00552,,YES,81,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.427,-3.894,2.467,,0.46,E,A,0.55,-0.14,0.374,,63.64,HHA,-1.50567,0.520039,0.00805839,0.648259 kka2_1:1_L81H,kka2_1:1_81,Kka2,kka2_1:1,P00552,,YES,81,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.427,-5.02,3.593,,0.46,E,A,0.55,-0.14,0.374,,63.64,HHA,-1.50567,0.520039,0.00805839,0.643152 kka2_1:1_L81S,kka2_1:1_81,Kka2,kka2_1:1,P00552,,YES,81,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.427,-3.746,2.319,,0.46,E,A,0.55,-0.14,0.374,,63.64,HHA,-1.50567,0.520039,0.00805839,0.645896 kka2_1:1_L81T,kka2_1:1_81,Kka2,kka2_1:1,P00552,,YES,81,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.427,-3.556,2.129,,0.46,E,A,0.55,-0.14,0.374,,63.64,HHA,-1.50567,0.520039,0.00805839,0.647469 kka2_1:1_L81Y,kka2_1:1_81,Kka2,kka2_1:1,P00552,,YES,81,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.427,-4.125,2.698,,0.46,E,A,0.55,-0.14,0.374,,63.64,HHA,-1.50567,0.520039,0.00805839,0.642358 kka2_1:1_L92A,kka2_1:1_92,Kka2,kka2_1:1,P00552,,YES,92,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.893,-3.128,2.235,,0.007,E,B,0.55,-0.19,1.447,,63.26,HHH,-0.962,0.520039,0.00307177,0.457588 kka2_1:1_L92C,kka2_1:1_92,Kka2,kka2_1:1,P00552,,YES,92,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.893,-4.72,3.827,,0.007,E,B,0.55,-0.19,1.447,,63.26,HHH,-0.962,0.520039,0.00307177,0.569253 kka2_1:1_L92D,kka2_1:1_92,Kka2,kka2_1:1,P00552,,YES,92,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.893,-4.173,3.28,,0.007,E,B,0.55,-0.19,1.447,,63.26,HHH,-0.962,0.520039,0.00307177,0.408258 kka2_1:1_L92G,kka2_1:1_92,Kka2,kka2_1:1,P00552,,YES,92,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.893,-3.838,2.945,,0.007,E,B,0.55,-0.19,1.447,,63.26,HHH,-0.962,0.520039,0.00307177,0.472526 kka2_1:1_L92I,kka2_1:1_92,Kka2,kka2_1:1,P00552,,YES,92,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.893,-2.953,2.06,,0.007,E,B,0.55,-0.19,1.447,,63.26,HHH,-0.962,0.520039,0.00307177,0.4688 kka2_1:1_L92K,kka2_1:1_92,Kka2,kka2_1:1,P00552,,YES,92,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.893,-3.743,2.85,,0.007,E,B,0.55,-0.19,1.447,,63.26,HHH,-0.962,0.520039,0.00307177,0.419799 kka2_1:1_L92N,kka2_1:1_92,Kka2,kka2_1:1,P00552,,YES,92,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.893,-4.184,3.291,,0.007,E,B,0.55,-0.19,1.447,,63.26,HHH,-0.962,0.520039,0.00307177,0.405228 kka2_1:1_L92S,kka2_1:1_92,Kka2,kka2_1:1,P00552,,YES,92,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.893,-3.672,2.779,,0.007,E,B,0.55,-0.19,1.447,,63.26,HHH,-0.962,0.520039,0.00307177,0.465124 kka2_1:1_L93C,kka2_1:1_93,Kka2,kka2_1:1,P00552,,YES,93,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.815,-4.726,3.911,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.520039,0.00131498,0.5622 kka2_1:1_L93D,kka2_1:1_93,Kka2,kka2_1:1,P00552,,YES,93,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.815,-4.139,3.324,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.520039,0.00131498,0.447201 kka2_1:1_L93E,kka2_1:1_93,Kka2,kka2_1:1,P00552,,YES,93,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.815,-3.848,3.033,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.520039,0.00131498,0.433661 kka2_1:1_L93G,kka2_1:1_93,Kka2,kka2_1:1,P00552,,YES,93,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.815,-3.804,2.989,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.520039,0.00131498,0.513284 kka2_1:1_L93K,kka2_1:1_93,Kka2,kka2_1:1,P00552,,YES,93,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.815,-3.596,2.781,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.520039,0.00131498,0.456413 kka2_1:1_L93N,kka2_1:1_93,Kka2,kka2_1:1,P00552,,YES,93,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.815,-4.082,3.267,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.520039,0.00131498,0.418188 kka2_1:1_L93S,kka2_1:1_93,Kka2,kka2_1:1,P00552,,YES,93,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.815,-3.637,2.822,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.520039,0.00131498,0.50708 kka2_1:1_L93T,kka2_1:1_93,Kka2,kka2_1:1,P00552,,YES,93,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.815,-3.473,2.658,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.520039,0.00131498,0.536099 kka2_1:1_L93W,kka2_1:1_93,Kka2,kka2_1:1,P00552,,YES,93,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.815,-5.169,4.354,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.520039,0.00131498,0.404146 kka2_1:1_L93Y,kka2_1:1_93,Kka2,kka2_1:1,P00552,,YES,93,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.815,-4.01,3.195,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.520039,0.00131498,0.435111 kka2_1:1_M120C,kka2_1:1_120,Kka2,kka2_1:1,P00552,,YES,120,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-3.877,-4.689,0.812,,,H,A,0.55,-0.42,2.259,,92.05,HHB,-2.16733,0.520039,0.00265808,0.599765 kka2_1:1_M120D,kka2_1:1_120,Kka2,kka2_1:1,P00552,,YES,120,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-3.877,-4.17,0.293,,,H,A,0.55,-0.42,2.259,,92.05,HHB,-2.16733,0.520039,0.00265808,0.504023 kka2_1:1_M120E,kka2_1:1_120,Kka2,kka2_1:1,P00552,,YES,120,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-3.877,-3.916,0.039,,,H,A,0.55,-0.42,2.259,,92.05,HHB,-2.16733,0.520039,0.00265808,0.487575 kka2_1:1_M120F,kka2_1:1_120,Kka2,kka2_1:1,P00552,,YES,120,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-3.877,-3.689,-0.188,,,H,A,0.55,-0.42,2.259,,92.05,HHB,-2.16733,0.520039,0.00265808,0.494347 kka2_1:1_M120G,kka2_1:1_120,Kka2,kka2_1:1,P00552,,YES,120,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-3.877,-3.835,-0.042,,,H,A,0.55,-0.42,2.259,,92.05,HHB,-2.16733,0.520039,0.00265808,0.455097 kka2_1:1_M120H,kka2_1:1_120,Kka2,kka2_1:1,P00552,,YES,120,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-3.877,-4.957,1.08,,,H,A,0.55,-0.42,2.259,,92.05,HHB,-2.16733,0.520039,0.00265808,0.620455 kka2_1:1_M120N,kka2_1:1_120,Kka2,kka2_1:1,P00552,,YES,120,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-3.877,-4.174,0.297,,,H,A,0.55,-0.42,2.259,,92.05,HHB,-2.16733,0.520039,0.00265808,0.516042 kka2_1:1_M120P,kka2_1:1_120,Kka2,kka2_1:1,P00552,,YES,120,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-3.877,-4.131,0.254,,,H,A,0.55,-0.42,2.259,,92.05,HHB,-2.16733,0.520039,0.00265808,0.448009 kka2_1:1_M120Q,kka2_1:1_120,Kka2,kka2_1:1,P00552,,YES,120,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-3.877,-4.176,0.299,,,H,A,0.55,-0.42,2.259,,92.05,HHB,-2.16733,0.520039,0.00265808,0.526536 kka2_1:1_M120R,kka2_1:1_120,Kka2,kka2_1:1,P00552,,YES,120,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-3.877,-4.005,0.128,,,H,A,0.55,-0.42,2.259,,92.05,HHB,-2.16733,0.520039,0.00265808,0.509099 kka2_1:1_M120Y,kka2_1:1_120,Kka2,kka2_1:1,P00552,,YES,120,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-3.877,-3.989,0.112,,,H,A,0.55,-0.42,2.259,,92.05,HHB,-2.16733,0.520039,0.00265808,0.503777 kka2_1:1_M148C,kka2_1:1_148,Kka2,kka2_1:1,P00552,,YES,148,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.847,-4.865,3.018,,0.268,H,A,1.59,0.71,4.618,,64.39,BHA,-1.65467,0.520039,0.00982664,0.571586 kka2_1:1_M148E,kka2_1:1_148,Kka2,kka2_1:1,P00552,,YES,148,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.847,-3.876,2.029,,0.268,H,A,1.59,0.71,4.618,,64.39,BHA,-1.65467,0.520039,0.00982664,0.453634 kka2_1:1_M148G,kka2_1:1_148,Kka2,kka2_1:1,P00552,,YES,148,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.847,-3.731,1.884,,0.268,H,A,1.59,0.71,4.618,,64.39,BHA,-1.65467,0.520039,0.00982664,0.451726 kka2_1:1_M148H,kka2_1:1_148,Kka2,kka2_1:1,P00552,,YES,148,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.847,-4.993,3.146,,0.268,H,A,1.59,0.71,4.618,,64.39,BHA,-1.65467,0.520039,0.00982664,0.50446 kka2_1:1_M148R,kka2_1:1_148,Kka2,kka2_1:1,P00552,,YES,148,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.847,-3.206,1.359,,0.268,H,A,1.59,0.71,4.618,,64.39,BHA,-1.65467,0.520039,0.00982664,0.529665 kka2_1:1_M178K,kka2_1:1_178,Kka2,kka2_1:1,P00552,,YES,178,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-3.206,-2.451,-0.755,,0.554,.,b,0.55,0.68,3.152,,71.59,BHO,-2.154,0.520039,0.00717253,0.836941 kka2_1:1_M178N,kka2_1:1_178,Kka2,kka2_1:1,P00552,,YES,178,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-3.206,-3.899,0.693,,0.554,.,b,0.55,0.68,3.152,,71.59,BHO,-2.154,0.520039,0.00717253,0.700752 kka2_1:1_M178P,kka2_1:1_178,Kka2,kka2_1:1,P00552,,YES,178,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-3.206,-3.217,0.011,,0.554,.,b,0.55,0.68,3.152,,71.59,BHO,-2.154,0.520039,0.00717253,0.679107 kka2_1:1_M1A,kka2_1:1_1,Kka2,kka2_1:1,P00552,,YES,1,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.787,-2.808,1.021,,,,,,,3.101,,62.12,NAHH,-1.787,0.520039,0.00251939,0.830578 kka2_1:1_M1C,kka2_1:1_1,Kka2,kka2_1:1,P00552,,YES,1,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.787,-4.448,2.661,,,,,,,3.101,,62.12,NAHH,-1.787,0.520039,0.00251939,0.884741 kka2_1:1_M1D,kka2_1:1_1,Kka2,kka2_1:1,P00552,,YES,1,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.787,-3.73,1.943,,,,,,,3.101,,62.12,NAHH,-1.787,0.520039,0.00251939,0.846006 kka2_1:1_M1E,kka2_1:1_1,Kka2,kka2_1:1,P00552,,YES,1,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.787,-3.476,1.689,,,,,,,3.101,,62.12,NAHH,-1.787,0.520039,0.00251939,0.806803 kka2_1:1_M1F,kka2_1:1_1,Kka2,kka2_1:1,P00552,,YES,1,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.787,-3.498,1.711,,,,,,,3.101,,62.12,NAHH,-1.787,0.520039,0.00251939,0.813619 kka2_1:1_M1G,kka2_1:1_1,Kka2,kka2_1:1,P00552,,YES,1,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.787,-3.394,1.607,,,,,,,3.101,,62.12,NAHH,-1.787,0.520039,0.00251939,0.812504 kka2_1:1_M1H,kka2_1:1_1,Kka2,kka2_1:1,P00552,,YES,1,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.787,-4.561,2.774,,,,,,,3.101,,62.12,NAHH,-1.787,0.520039,0.00251939,0.862839 kka2_1:1_M1K,kka2_1:1_1,Kka2,kka2_1:1,P00552,,YES,1,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.787,-3.337,1.55,,,,,,,3.101,,62.12,NAHH,-1.787,0.520039,0.00251939,0.815538 kka2_1:1_M1N,kka2_1:1_1,Kka2,kka2_1:1,P00552,,YES,1,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.787,-3.778,1.991,,,,,,,3.101,,62.12,NAHH,-1.787,0.520039,0.00251939,0.86147 kka2_1:1_M1P,kka2_1:1_1,Kka2,kka2_1:1,P00552,,YES,1,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.787,-3.691,1.904,,,,,,,3.101,,62.12,NAHH,-1.787,0.520039,0.00251939,0.829833 kka2_1:1_M1Q,kka2_1:1_1,Kka2,kka2_1:1,P00552,,YES,1,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.787,-3.614,1.827,,,,,,,3.101,,62.12,NAHH,-1.787,0.520039,0.00251939,0.822136 kka2_1:1_M1S,kka2_1:1_1,Kka2,kka2_1:1,P00552,,YES,1,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.787,-3.266,1.479,,,,,,,3.101,,62.12,NAHH,-1.787,0.520039,0.00251939,0.796503 kka2_1:1_M1W,kka2_1:1_1,Kka2,kka2_1:1,P00552,,YES,1,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.787,-4.812,3.025,,,,,,,3.101,,62.12,NAHH,-1.787,0.520039,0.00251939,0.857173 kka2_1:1_M1Y,kka2_1:1_1,Kka2,kka2_1:1,P00552,,YES,1,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.787,-3.748,1.961,,,,,,,3.101,,62.12,NAHH,-1.787,0.520039,0.00251939,0.85444 kka2_1:1_N58A,kka2_1:1_58,Kka2,kka2_1:1,P00552,,YES,58,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-2.641,-1.819,-0.822,,0.131,S,A,0.61,0.72,30.755,30.755,71.59,HPA,-1.83033,0.520039,0.00793425,0.905851 kka2_1:1_N58F,kka2_1:1_58,Kka2,kka2_1:1,P00552,,YES,58,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-2.641,-4.413,1.772,,0.131,S,A,0.61,0.72,30.755,30.755,71.59,HPA,-1.83033,0.520039,0.00793425,0.67996 kka2_1:1_N58G,kka2_1:1_58,Kka2,kka2_1:1,P00552,,YES,58,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-2.641,-1.779,-0.862,,0.131,S,A,0.61,0.72,30.755,30.755,71.59,HPA,-1.83033,0.520039,0.00793425,0.886061 kka2_1:1_N58H,kka2_1:1_58,Kka2,kka2_1:1,P00552,,YES,58,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-2.641,-4.779,2.138,,0.131,S,A,0.61,0.72,30.755,30.755,71.59,HPA,-1.83033,0.520039,0.00793425,0.766374 kka2_1:1_N58I,kka2_1:1_58,Kka2,kka2_1:1,P00552,,YES,58,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-2.641,-4.075,1.434,,0.131,S,A,0.61,0.72,30.755,30.755,71.59,HPA,-1.83033,0.520039,0.00793425,0.681613 kka2_1:1_N58L,kka2_1:1_58,Kka2,kka2_1:1,P00552,,YES,58,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-2.641,-3.653,1.012,,0.131,S,A,0.61,0.72,30.755,30.755,71.59,HPA,-1.83033,0.520039,0.00793425,0.658442 kka2_1:1_N58M,kka2_1:1_58,Kka2,kka2_1:1,P00552,,YES,58,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-2.641,-4.871,2.23,,0.131,S,A,0.61,0.72,30.755,30.755,71.59,HPA,-1.83033,0.520039,0.00793425,0.763909 kka2_1:1_N58P,kka2_1:1_58,Kka2,kka2_1:1,P00552,,YES,58,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-2.641,-4.016,1.375,,0.131,S,A,0.61,0.72,30.755,30.755,71.59,HPA,-1.83033,0.520039,0.00793425,0.589395 kka2_1:1_N58Q,kka2_1:1_58,Kka2,kka2_1:1,P00552,,YES,58,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-2.641,-4.107,1.466,,0.131,S,A,0.61,0.72,30.755,30.755,71.59,HPA,-1.83033,0.520039,0.00793425,0.69938 kka2_1:1_N58R,kka2_1:1_58,Kka2,kka2_1:1,P00552,,YES,58,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-2.641,-3.198,0.557,,0.131,S,A,0.61,0.72,30.755,30.755,71.59,HPA,-1.83033,0.520039,0.00793425,0.751742 kka2_1:1_N58V,kka2_1:1_58,Kka2,kka2_1:1,P00552,,YES,58,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-2.641,-3.703,1.062,,0.131,S,A,0.61,0.72,30.755,30.755,71.59,HPA,-1.83033,0.520039,0.00793425,0.656429 kka2_1:1_N58W,kka2_1:1_58,Kka2,kka2_1:1,P00552,,YES,58,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-2.641,-5.525,2.884,,0.131,S,A,0.61,0.72,30.755,30.755,71.59,HPA,-1.83033,0.520039,0.00793425,0.768918 kka2_1:1_P109E,kka2_1:1_109,Kka2,kka2_1:1,P00552,,YES,109,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.412,-2.892,1.48,,0.376,H,A,0.52,-1.25,18.506,18.506,65.53,HOH,-1.84567,0.520039,0.0070929,0.54976 kka2_1:1_P109G,kka2_1:1_109,Kka2,kka2_1:1,P00552,,YES,109,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.412,-3.439,2.027,,0.376,H,A,0.52,-1.25,18.506,18.506,65.53,HOH,-1.84567,0.520039,0.0070929,0.524231 kka2_1:1_P109W,kka2_1:1_109,Kka2,kka2_1:1,P00552,,YES,109,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.412,-3.457,2.045,,0.376,H,A,0.52,-1.25,18.506,18.506,65.53,HOH,-1.84567,0.520039,0.0070929,0.501607 kka2_1:1_P128D,kka2_1:1_128,Kka2,kka2_1:1,P00552,,YES,128,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.922,-4.006,2.084,,0.316,G,A,0.52,0.4,2.178,,56.06,AOH,-1.64733,0.520039,0.00774689,0.413728 kka2_1:1_P128G,kka2_1:1_128,Kka2,kka2_1:1,P00552,,YES,128,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.922,-3.745,1.823,,0.316,G,A,0.52,0.4,2.178,,56.06,AOH,-1.64733,0.520039,0.00774689,0.42158 kka2_1:1_P128K,kka2_1:1_128,Kka2,kka2_1:1,P00552,,YES,128,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.922,-3.891,1.969,,0.316,G,A,0.52,0.4,2.178,,56.06,AOH,-1.64733,0.520039,0.00774689,0.41864 kka2_1:1_P128N,kka2_1:1_128,Kka2,kka2_1:1,P00552,,YES,128,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.922,-4.215,2.293,,0.316,G,A,0.52,0.4,2.178,,56.06,AOH,-1.64733,0.520039,0.00774689,0.451777 kka2_1:1_P128Y,kka2_1:1_128,Kka2,kka2_1:1,P00552,,YES,128,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.922,-3.242,1.32,,0.316,G,A,0.52,0.4,2.178,,56.06,AOH,-1.64733,0.520039,0.00774689,0.484764 kka2_1:1_P12N,kka2_1:1_12,Kka2,kka2_1:1,P00552,,YES,12,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.853,-3.936,3.083,,,.,B,0.52,1.25,0.261,,48.11,POH,-1.80767,0.520039,0.00500011,0.450385 kka2_1:1_P132C,kka2_1:1_132,Kka2,kka2_1:1,P00552,,YES,132,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.775,-5.083,4.308,,0.692,.,A,0.52,0.56,0.224,,44.7,OOH,-0.825667,0.520039,0.0018489,0.5385 kka2_1:1_P132E,kka2_1:1_132,Kka2,kka2_1:1,P00552,,YES,132,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.775,-3.466,2.691,,0.692,.,A,0.52,0.56,0.224,,44.7,OOH,-0.825667,0.520039,0.0018489,0.457176 kka2_1:1_P132F,kka2_1:1_132,Kka2,kka2_1:1,P00552,,YES,132,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.775,-4.513,3.738,,0.692,.,A,0.52,0.56,0.224,,44.7,OOH,-0.825667,0.520039,0.0018489,0.460626 kka2_1:1_P132N,kka2_1:1_132,Kka2,kka2_1:1,P00552,,YES,132,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.775,-3.857,3.082,,0.692,.,A,0.52,0.56,0.224,,44.7,OOH,-0.825667,0.520039,0.0018489,0.474522 kka2_1:1_P132Y,kka2_1:1_132,Kka2,kka2_1:1,P00552,,YES,132,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.775,-4.414,3.639,,0.692,.,A,0.52,0.56,0.224,,44.7,OOH,-0.825667,0.520039,0.0018489,0.457236 kka2_1:1_P167C,kka2_1:1_167,Kka2,kka2_1:1,P00552,,YES,167,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-2.403,-4.818,2.415,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.520039,0.00543203,0.703208 kka2_1:1_P167F,kka2_1:1_167,Kka2,kka2_1:1,P00552,,YES,167,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-2.403,-4.229,1.826,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.520039,0.00543203,0.58253 kka2_1:1_P167Y,kka2_1:1_167,Kka2,kka2_1:1,P00552,,YES,167,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-2.403,-4.35,1.947,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.520039,0.00543203,0.607749 kka2_1:1_P249C,kka2_1:1_249,Kka2,kka2_1:1,P00552,,YES,249,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.867,-5.002,3.135,,0.406,.,B,0.52,-0.01,8.037,8.037,92.05,HOA,-1.66867,0.520039,0.011045,0.800658 kka2_1:1_P249D,kka2_1:1_249,Kka2,kka2_1:1,P00552,,YES,249,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.867,-3.169,1.302,,0.406,.,B,0.52,-0.01,8.037,8.037,92.05,HOA,-1.66867,0.520039,0.011045,0.685203 kka2_1:1_P249G,kka2_1:1_249,Kka2,kka2_1:1,P00552,,YES,249,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.867,-3.661,1.794,,0.406,.,B,0.52,-0.01,8.037,8.037,92.05,HOA,-1.66867,0.520039,0.011045,0.72418 kka2_1:1_P249N,kka2_1:1_249,Kka2,kka2_1:1,P00552,,YES,249,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.867,-4.142,2.275,,0.406,.,B,0.52,-0.01,8.037,8.037,92.05,HOA,-1.66867,0.520039,0.011045,0.80634 kka2_1:1_P249Y,kka2_1:1_249,Kka2,kka2_1:1,P00552,,YES,249,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.867,-4.279,2.412,,0.406,.,B,0.52,-0.01,8.037,8.037,92.05,HOA,-1.66867,0.520039,0.011045,0.797348 kka2_1:1_P98I,kka2_1:1_98,Kka2,kka2_1:1,P00552,,YES,98,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.526,-4.079,2.553,,0.391,S,B,0.52,-0.65,1.521,,63.26,HOO,-1.19167,0.520039,0.00622754,0.45577 kka2_1:1_P98W,kka2_1:1_98,Kka2,kka2_1:1,P00552,,YES,98,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.526,-5.629,4.103,,0.391,S,B,0.52,-0.65,1.521,,63.26,HOO,-1.19167,0.520039,0.00622754,0.488955 kka2_1:1_Q100F,kka2_1:1_100,Kka2,kka2_1:1,P00552,,YES,100,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.77,-4.378,1.608,,0.646,E,B,0.4,-0.79,15.116,15.116,71.59,OPA,-1.46467,0.520039,0.0066405,0.726897 kka2_1:1_Q155C,kka2_1:1_155,Kka2,kka2_1:1,P00552,,YES,155,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.606,-5.171,2.565,,0.525,T,A,0.4,1.49,4.415,,63.64,APA,-1.726,0.520039,0.00641853,0.884471 kka2_1:1_Q155I,kka2_1:1_155,Kka2,kka2_1:1,P00552,,YES,155,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.606,-3.926,1.32,,0.525,T,A,0.4,1.49,4.415,,63.64,APA,-1.726,0.520039,0.00641853,0.750995 kka2_1:1_Q155T,kka2_1:1_155,Kka2,kka2_1:1,P00552,,YES,155,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.606,-3.529,0.923,,0.525,T,A,0.4,1.49,4.415,,63.64,APA,-1.726,0.520039,0.00641853,0.832327 kka2_1:1_Q163S,kka2_1:1_163,Kka2,kka2_1:1,P00552,,YES,163,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.162,-3.535,1.373,,0.58,T,B,0.64,1.85,2.779,,64.02,BPO,-1.78333,0.520039,0.00719507,0.764961 kka2_1:1_Q252I,kka2_1:1_252,Kka2,kka2_1:1,P00552,,YES,252,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.63,-4.083,1.453,,0.906,H,A,0.64,0.35,1.369,,92.05,PPB,-2.20733,0.520039,0.0121001,0.837048 kka2_1:1_Q252S,kka2_1:1_252,Kka2,kka2_1:1,P00552,,YES,252,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.63,-2.755,0.125,,0.906,H,A,0.64,0.35,1.369,,92.05,PPB,-2.20733,0.520039,0.0121001,0.874551 kka2_1:1_Q26I,kka2_1:1_26,Kka2,kka2_1:1,P00552,,YES,26,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.18,-4.055,1.875,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.520039,0.00708962,0.701463 kka2_1:1_Q26S,kka2_1:1_26,Kka2,kka2_1:1,P00552,,YES,26,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.18,-3.511,1.331,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.520039,0.00708962,0.713346 kka2_1:1_Q27C,kka2_1:1_27,Kka2,kka2_1:1,P00552,,YES,27,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-1.659,-5.15,3.491,,0.608,.,A,0.64,0.71,0.521,,65.53,PPP,-1.90733,0.520039,0.00595365,0.677529 kka2_1:1_Q27G,kka2_1:1_27,Kka2,kka2_1:1,P00552,,YES,27,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-1.659,-3.564,1.905,,0.608,.,A,0.64,0.71,0.521,,65.53,PPP,-1.90733,0.520039,0.00595365,0.670351 kka2_1:1_Q27V,kka2_1:1_27,Kka2,kka2_1:1,P00552,,YES,27,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-1.659,-2.648,0.989,,0.608,.,A,0.64,0.71,0.521,,65.53,PPP,-1.90733,0.520039,0.00595365,0.672702 kka2_1:1_Q42A,kka2_1:1_42,Kka2,kka2_1:1,P00552,,YES,42,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.907,-2.221,-0.686,,1.044,T,B,0.4,-0.8,2.792,,71.59,HPO,-2.12433,0.520039,0.00679212,0.986023 kka2_1:1_Q42D,kka2_1:1_42,Kka2,kka2_1:1,P00552,,YES,42,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.907,-2.294,-0.613,,1.044,T,B,0.4,-0.8,2.792,,71.59,HPO,-2.12433,0.520039,0.00679212,0.979757 kka2_1:1_Q42F,kka2_1:1_42,Kka2,kka2_1:1,P00552,,YES,42,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.907,-4.511,1.604,,1.044,T,B,0.4,-0.8,2.792,,71.59,HPO,-2.12433,0.520039,0.00679212,0.778481 kka2_1:1_Q42V,kka2_1:1_42,Kka2,kka2_1:1,P00552,,YES,42,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.907,-3.778,0.871,,1.044,T,B,0.4,-0.8,2.792,,71.59,HPO,-2.12433,0.520039,0.00679212,0.779136 kka2_1:1_Q42W,kka2_1:1_42,Kka2,kka2_1:1,P00552,,YES,42,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.907,-5.634,2.727,,1.044,T,B,0.4,-0.8,2.792,,71.59,HPO,-2.12433,0.520039,0.00679212,0.772626 kka2_1:1_Q4G,kka2_1:1_4,Kka2,kka2_1:1,P00552,,YES,4,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.361,-1.897,-0.464,,,,,,,5.615,,71.59,APA,-1.95533,0.520039,0.00239179,1.05096 kka2_1:1_Q61I,kka2_1:1_61,Kka2,kka2_1:1,P00552,,YES,61,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.982,-3.937,0.955,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.520039,0.00612092,0.753127 kka2_1:1_Q61M,kka2_1:1_61,Kka2,kka2_1:1,P00552,,YES,61,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.982,-4.764,1.782,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.520039,0.00612092,0.773255 kka2_1:1_Q61N,kka2_1:1_61,Kka2,kka2_1:1,P00552,,YES,61,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.982,-3.133,0.151,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.520039,0.00612092,0.848484 kka2_1:1_Q61T,kka2_1:1_61,Kka2,kka2_1:1,P00552,,YES,61,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.982,-2.975,-0.007,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.520039,0.00612092,0.851762 kka2_1:1_Q61V,kka2_1:1_61,Kka2,kka2_1:1,P00552,,YES,61,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.982,-2.81,-0.172,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.520039,0.00612092,0.882333 kka2_1:1_Q61Y,kka2_1:1_61,Kka2,kka2_1:1,P00552,,YES,61,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.982,-4.455,1.473,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.520039,0.00612092,0.771068 kka2_1:1_R121A,kka2_1:1_121,Kka2,kka2_1:1,P00552,,YES,121,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.552,-2.713,1.161,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.520039,0.00523326,0.636479 kka2_1:1_R121E,kka2_1:1_121,Kka2,kka2_1:1,P00552,,YES,121,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.552,-2.795,1.243,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.520039,0.00523326,0.616769 kka2_1:1_R121F,kka2_1:1_121,Kka2,kka2_1:1,P00552,,YES,121,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.552,-4.32,2.768,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.520039,0.00523326,0.570472 kka2_1:1_R121I,kka2_1:1_121,Kka2,kka2_1:1,P00552,,YES,121,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.552,-3.978,2.426,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.520039,0.00523326,0.531623 kka2_1:1_R121K,kka2_1:1_121,Kka2,kka2_1:1,P00552,,YES,121,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.552,-2.242,0.69,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.520039,0.00523326,0.709263 kka2_1:1_R121M,kka2_1:1_121,Kka2,kka2_1:1,P00552,,YES,121,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.552,-4.593,3.041,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.520039,0.00523326,0.590629 kka2_1:1_R121N,kka2_1:1_121,Kka2,kka2_1:1,P00552,,YES,121,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.552,-3.678,2.126,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.520039,0.00523326,0.599923 kka2_1:1_R121T,kka2_1:1_121,Kka2,kka2_1:1,P00552,,YES,121,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.552,-3.59,2.038,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.520039,0.00523326,0.618852 kka2_1:1_R121V,kka2_1:1_121,Kka2,kka2_1:1,P00552,,YES,121,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.552,-3.699,2.147,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.520039,0.00523326,0.608442 kka2_1:1_R121Y,kka2_1:1_121,Kka2,kka2_1:1,P00552,,YES,121,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.552,-4.18,2.628,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.520039,0.00523326,0.571379 kka2_1:1_R122A,kka2_1:1_122,Kka2,kka2_1:1,P00552,,YES,122,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.175,-2.209,0.034,,0.487,H,A,1.2,0.26,1.356,,71.59,BBH,-1.53833,0.520039,0.00736512,0.816335 kka2_1:1_R122E,kka2_1:1_122,Kka2,kka2_1:1,P00552,,YES,122,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.175,-2.696,0.521,,0.487,H,A,1.2,0.26,1.356,,71.59,BBH,-1.53833,0.520039,0.00736512,0.734503 kka2_1:1_R122F,kka2_1:1_122,Kka2,kka2_1:1,P00552,,YES,122,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.175,-4.454,2.279,,0.487,H,A,1.2,0.26,1.356,,71.59,BBH,-1.53833,0.520039,0.00736512,0.730026 kka2_1:1_R122I,kka2_1:1_122,Kka2,kka2_1:1,P00552,,YES,122,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.175,-4.03,1.855,,0.487,H,A,1.2,0.26,1.356,,71.59,BBH,-1.53833,0.520039,0.00736512,0.658684 kka2_1:1_R122K,kka2_1:1_122,Kka2,kka2_1:1,P00552,,YES,122,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.175,-3.561,1.386,,0.487,H,A,1.2,0.26,1.356,,71.59,BBH,-1.53833,0.520039,0.00736512,0.67576 kka2_1:1_R122M,kka2_1:1_122,Kka2,kka2_1:1,P00552,,YES,122,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.175,-3.353,1.178,,0.487,H,A,1.2,0.26,1.356,,71.59,BBH,-1.53833,0.520039,0.00736512,0.671113 kka2_1:1_R122V,kka2_1:1_122,Kka2,kka2_1:1,P00552,,YES,122,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.175,-2.949,0.774,,0.487,H,A,1.2,0.26,1.356,,71.59,BBH,-1.53833,0.520039,0.00736512,0.73322 kka2_1:1_R122Y,kka2_1:1_122,Kka2,kka2_1:1,P00552,,YES,122,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.175,-4.411,2.236,,0.487,H,A,1.2,0.26,1.356,,71.59,BBH,-1.53833,0.520039,0.00736512,0.73399 kka2_1:1_R140I,kka2_1:1_140,Kka2,kka2_1:1,P00552,,YES,140,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.351,-4.1,2.749,,0.12,H,A,1.2,0.2,11.345,11.345,53.03,BBH,-1.885,0.520039,0.00430167,0.43708 kka2_1:1_R143M,kka2_1:1_143,Kka2,kka2_1:1,P00552,,YES,143,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.525,-4.625,2.1,,0.325,H,A,0.16,1.22,3.6,,65.53,ABH,-1.86833,0.520039,0.00662247,0.804117 kka2_1:1_R143W,kka2_1:1_143,Kka2,kka2_1:1,P00552,,YES,143,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.525,-5.57,3.045,,0.325,H,A,0.16,1.22,3.6,,65.53,ABH,-1.86833,0.520039,0.00662247,0.793686 kka2_1:1_R145D,kka2_1:1_145,Kka2,kka2_1:1,P00552,,YES,145,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.804,-3.693,1.889,,0.346,H,A,1.2,1.23,23.699,23.699,63.64,HBP,-1.88033,0.520039,0.00846663,0.600263 kka2_1:1_R145F,kka2_1:1_145,Kka2,kka2_1:1,P00552,,YES,145,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.804,-4.396,2.592,,0.346,H,A,1.2,1.23,23.699,23.699,63.64,HBP,-1.88033,0.520039,0.00846663,0.602559 kka2_1:1_R145V,kka2_1:1_145,Kka2,kka2_1:1,P00552,,YES,145,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.804,-3.111,1.307,,0.346,H,A,1.2,1.23,23.699,23.699,63.64,HBP,-1.88033,0.520039,0.00846663,0.680401 kka2_1:1_R145Y,kka2_1:1_145,Kka2,kka2_1:1,P00552,,YES,145,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.804,-4.267,2.463,,0.346,H,A,1.2,1.23,23.699,23.699,63.64,HBP,-1.88033,0.520039,0.00846663,0.563909 kka2_1:1_R147A,kka2_1:1_147,Kka2,kka2_1:1,P00552,,YES,147,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.123,-3.267,2.144,,0.094,H,A,1.2,0.97,2.578,,64.02,PBH,-1.98267,0.520039,0.00549168,0.549066 kka2_1:1_R147D,kka2_1:1_147,Kka2,kka2_1:1,P00552,,YES,147,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.123,-3.649,2.526,,0.094,H,A,1.2,0.97,2.578,,64.02,PBH,-1.98267,0.520039,0.00549168,0.488981 kka2_1:1_R147E,kka2_1:1_147,Kka2,kka2_1:1,P00552,,YES,147,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.123,-3.304,2.181,,0.094,H,A,1.2,0.97,2.578,,64.02,PBH,-1.98267,0.520039,0.00549168,0.538256 kka2_1:1_R147M,kka2_1:1_147,Kka2,kka2_1:1,P00552,,YES,147,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.123,-4.65,3.527,,0.094,H,A,1.2,0.97,2.578,,64.02,PBH,-1.98267,0.520039,0.00549168,0.520706 kka2_1:1_R147Y,kka2_1:1_147,Kka2,kka2_1:1,P00552,,YES,147,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.123,-4.044,2.921,,0.094,H,A,1.2,0.97,2.578,,64.02,PBH,-1.98267,0.520039,0.00549168,0.483045 kka2_1:1_R18A,kka2_1:1_18,Kka2,kka2_1:1,P00552,,YES,18,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.055,-2.49,0.435,,0.474,T,A,1.2,0.54,11.422,11.422,71.59,ABH,-1.821,0.520039,0.00724065,0.859236 kka2_1:1_R18D,kka2_1:1_18,Kka2,kka2_1:1,P00552,,YES,18,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.055,-2.8,0.745,,0.474,T,A,1.2,0.54,11.422,11.422,71.59,ABH,-1.821,0.520039,0.00724065,0.817162 kka2_1:1_R18K,kka2_1:1_18,Kka2,kka2_1:1,P00552,,YES,18,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.055,-2.865,0.81,,0.474,T,A,1.2,0.54,11.422,11.422,71.59,ABH,-1.821,0.520039,0.00724065,0.885034 kka2_1:1_R202K,kka2_1:1_202,Kka2,kka2_1:1,P00552,,YES,202,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.761,-2.914,1.153,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.520039,0.00696498,0.662822 kka2_1:1_R202Y,kka2_1:1_202,Kka2,kka2_1:1,P00552,,YES,202,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.761,-4.316,2.555,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.520039,0.00696498,0.515438 kka2_1:1_R211I,kka2_1:1_211,Kka2,kka2_1:1,P00552,,YES,211,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-0.899,-4.062,3.163,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.520039,0.00204888,0.423273 kka2_1:1_R239M,kka2_1:1_239,Kka2,kka2_1:1,P00552,,YES,239,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.949,-4.723,1.774,,0.15,H,A,1.2,-0.31,0.477,,71.59,ABH,-2.23,0.520039,0.00835326,0.662717 kka2_1:1_R38A,kka2_1:1_38,Kka2,kka2_1:1,P00552,,YES,38,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.207,-3.17,1.963,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.520039,0.00372499,0.549466 kka2_1:1_R44N,kka2_1:1_44,Kka2,kka2_1:1,P00552,,YES,44,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.062,-3.108,1.046,,0.487,S,B,1.2,-0.35,2.717,,71.59,OBO,-1.80767,0.520039,0.00745043,0.647456 kka2_1:1_R44Y,kka2_1:1_44,Kka2,kka2_1:1,P00552,,YES,44,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.062,-4.366,2.304,,0.487,S,B,1.2,-0.35,2.717,,71.59,OBO,-1.80767,0.520039,0.00745043,0.664499 kka2_1:1_R66D,kka2_1:1_66,Kka2,kka2_1:1,P00552,,YES,66,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-0.922,-3.72,2.798,,0.103,H,A,1.2,-0.2,2.659,,46.21,HBH,-1.13567,0.520039,0.00161025,0.415578 kka2_1:1_R66F,kka2_1:1_66,Kka2,kka2_1:1,P00552,,YES,66,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-0.922,-4.355,3.433,,0.103,H,A,1.2,-0.2,2.659,,46.21,HBH,-1.13567,0.520039,0.00161025,0.444814 kka2_1:1_R66G,kka2_1:1_66,Kka2,kka2_1:1,P00552,,YES,66,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-0.922,-3.421,2.499,,0.103,H,A,1.2,-0.2,2.659,,46.21,HBH,-1.13567,0.520039,0.00161025,0.478107 kka2_1:1_R66I,kka2_1:1_66,Kka2,kka2_1:1,P00552,,YES,66,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-0.922,-4.073,3.151,,0.103,H,A,1.2,-0.2,2.659,,46.21,HBH,-1.13567,0.520039,0.00161025,0.409508 kka2_1:1_R66M,kka2_1:1_66,Kka2,kka2_1:1,P00552,,YES,66,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-0.922,-4.542,3.62,,0.103,H,A,1.2,-0.2,2.659,,46.21,HBH,-1.13567,0.520039,0.00161025,0.449939 kka2_1:1_R66N,kka2_1:1_66,Kka2,kka2_1:1,P00552,,YES,66,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-0.922,-3.51,2.588,,0.103,H,A,1.2,-0.2,2.659,,46.21,HBH,-1.13567,0.520039,0.00161025,0.422446 kka2_1:1_R66P,kka2_1:1_66,Kka2,kka2_1:1,P00552,,YES,66,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-0.922,-3.906,2.984,,0.103,H,A,1.2,-0.2,2.659,,46.21,HBH,-1.13567,0.520039,0.00161025,0.451272 kka2_1:1_R89A,kka2_1:1_89,Kka2,kka2_1:1,P00552,,YES,89,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.548,-2.806,1.258,,0.209,E,B,0.16,1.41,14.396,14.396,64.39,OBA,-1.89867,0.520039,0.00524373,0.617382 kka2_1:1_R89D,kka2_1:1_89,Kka2,kka2_1:1,P00552,,YES,89,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.548,-3.735,2.187,,0.209,E,B,0.16,1.41,14.396,14.396,64.39,OBA,-1.89867,0.520039,0.00524373,0.561934 kka2_1:1_R89E,kka2_1:1_89,Kka2,kka2_1:1,P00552,,YES,89,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.548,-2.88,1.332,,0.209,E,B,0.16,1.41,14.396,14.396,64.39,OBA,-1.89867,0.520039,0.00524373,0.611532 kka2_1:1_R89F,kka2_1:1_89,Kka2,kka2_1:1,P00552,,YES,89,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.548,-3.236,1.688,,0.209,E,B,0.16,1.41,14.396,14.396,64.39,OBA,-1.89867,0.520039,0.00524373,0.578797 kka2_1:1_R89I,kka2_1:1_89,Kka2,kka2_1:1,P00552,,YES,89,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.548,-4.125,2.577,,0.209,E,B,0.16,1.41,14.396,14.396,64.39,OBA,-1.89867,0.520039,0.00524373,0.542631 kka2_1:1_R89K,kka2_1:1_89,Kka2,kka2_1:1,P00552,,YES,89,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.548,-2.811,1.263,,0.209,E,B,0.16,1.41,14.396,14.396,64.39,OBA,-1.89867,0.520039,0.00524373,0.634019 kka2_1:1_R89M,kka2_1:1_89,Kka2,kka2_1:1,P00552,,YES,89,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.548,-4.745,3.197,,0.209,E,B,0.16,1.41,14.396,14.396,64.39,OBA,-1.89867,0.520039,0.00524373,0.576588 kka2_1:1_R89P,kka2_1:1_89,Kka2,kka2_1:1,P00552,,YES,89,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.548,-4.076,2.528,,0.209,E,B,0.16,1.41,14.396,14.396,64.39,OBA,-1.89867,0.520039,0.00524373,0.553587 kka2_1:1_R89Q,kka2_1:1_89,Kka2,kka2_1:1,P00552,,YES,89,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.548,-2.675,1.127,,0.209,E,B,0.16,1.41,14.396,14.396,64.39,OBA,-1.89867,0.520039,0.00524373,0.662954 kka2_1:1_R89T,kka2_1:1_89,Kka2,kka2_1:1,P00552,,YES,89,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.548,-2.992,1.444,,0.209,E,B,0.16,1.41,14.396,14.396,64.39,OBA,-1.89867,0.520039,0.00524373,0.601077 kka2_1:1_R89V,kka2_1:1_89,Kka2,kka2_1:1,P00552,,YES,89,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.548,-3.804,2.256,,0.209,E,B,0.16,1.41,14.396,14.396,64.39,OBA,-1.89867,0.520039,0.00524373,0.58207 kka2_1:1_R89W,kka2_1:1_89,Kka2,kka2_1:1,P00552,,YES,89,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.548,-5.305,3.757,,0.209,E,B,0.16,1.41,14.396,14.396,64.39,OBA,-1.89867,0.520039,0.00524373,0.579855 kka2_1:1_R89Y,kka2_1:1_89,Kka2,kka2_1:1,P00552,,YES,89,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.548,-2.904,1.356,,0.209,E,B,0.16,1.41,14.396,14.396,64.39,OBA,-1.89867,0.520039,0.00524373,0.633349 kka2_1:1_S104F,kka2_1:1_104,Kka2,kka2_1:1,P00552,,YES,104,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.436,-4.301,2.865,,0.536,T,A,0.27,-1.11,5.49,,63.64,HPP,-1.91433,0.520039,0.00555207,0.511066 kka2_1:1_S104H,kka2_1:1_104,Kka2,kka2_1:1,P00552,,YES,104,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.436,-3.319,1.883,,0.536,T,A,0.27,-1.11,5.49,,63.64,HPP,-1.91433,0.520039,0.00555207,0.539221 kka2_1:1_S104M,kka2_1:1_104,Kka2,kka2_1:1,P00552,,YES,104,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.436,-4.687,3.251,,0.536,T,A,0.27,-1.11,5.49,,63.64,HPP,-1.91433,0.520039,0.00555207,0.547153 kka2_1:1_S105D,kka2_1:1_105,Kka2,kka2_1:1,P00552,,YES,105,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.945,-2.638,0.693,,0.056,S,B,0.27,-1.04,3.442,,65.53,PPB,-2.17033,0.520039,0.00847233,0.577156 kka2_1:1_S105V,kka2_1:1_105,Kka2,kka2_1:1,P00552,,YES,105,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.945,-2.997,1.052,,0.056,S,B,0.27,-1.04,3.442,,65.53,PPB,-2.17033,0.520039,0.00847233,0.476795 kka2_1:1_S105W,kka2_1:1_105,Kka2,kka2_1:1,P00552,,YES,105,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.945,-5.544,3.599,,0.056,S,B,0.27,-1.04,3.442,,65.53,PPB,-2.17033,0.520039,0.00847233,0.490482 kka2_1:1_S105Y,kka2_1:1_105,Kka2,kka2_1:1,P00552,,YES,105,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.945,-4.433,2.488,,0.056,S,B,0.27,-1.04,3.442,,65.53,PPB,-2.17033,0.520039,0.00847233,0.510617 kka2_1:1_S114A,kka2_1:1_114,Kka2,kka2_1:1,P00552,,YES,114,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.527,-2.102,-0.425,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.520039,0.00705262,1.03533 kka2_1:1_S114P,kka2_1:1_114,Kka2,kka2_1:1,P00552,,YES,114,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.527,-4.051,1.524,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.520039,0.00705262,0.600639 kka2_1:1_S114V,kka2_1:1_114,Kka2,kka2_1:1,P00552,,YES,114,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.527,-2.736,0.209,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.520039,0.00705262,0.840626 kka2_1:1_S114Y,kka2_1:1_114,Kka2,kka2_1:1,P00552,,YES,114,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.527,-4.358,1.831,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.520039,0.00705262,0.74107 kka2_1:1_S11D,kka2_1:1_11,Kka2,kka2_1:1,P00552,,YES,11,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.322,-3.766,1.444,,0.408,,B,0.77,1.64,2.054,,92.05,OPO,-1.69867,0.520039,0.00381691,0.769764 kka2_1:1_S11E,kka2_1:1_11,Kka2,kka2_1:1,P00552,,YES,11,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.322,-3.629,1.307,,0.408,,B,0.77,1.64,2.054,,92.05,OPO,-1.69867,0.520039,0.00381691,0.78569 kka2_1:1_S11F,kka2_1:1_11,Kka2,kka2_1:1,P00552,,YES,11,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.322,-3.896,1.574,,0.408,,B,0.77,1.64,2.054,,92.05,OPO,-1.69867,0.520039,0.00381691,0.796402 kka2_1:1_S11H,kka2_1:1_11,Kka2,kka2_1:1,P00552,,YES,11,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.322,-4.78,2.458,,0.408,,B,0.77,1.64,2.054,,92.05,OPO,-1.69867,0.520039,0.00381691,0.80644 kka2_1:1_S11K,kka2_1:1_11,Kka2,kka2_1:1,P00552,,YES,11,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.322,-3.575,1.253,,0.408,,B,0.77,1.64,2.054,,92.05,OPO,-1.69867,0.520039,0.00381691,0.816182 kka2_1:1_S11V,kka2_1:1_11,Kka2,kka2_1:1,P00552,,YES,11,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.322,-2.388,0.066,,0.408,,B,0.77,1.64,2.054,,92.05,OPO,-1.69867,0.520039,0.00381691,0.869472 kka2_1:1_S204P,kka2_1:1_204,Kka2,kka2_1:1,P00552,,YES,204,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.353,-3.82,2.467,,0.144,E,A,0.27,-1.2,3.022,,65.53,HPO,-0.953333,0.520039,0.00881794,0.455871 kka2_1:1_S204Q,kka2_1:1_204,Kka2,kka2_1:1,P00552,,YES,204,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.353,-3.954,2.601,,0.144,E,A,0.27,-1.2,3.022,,65.53,HPO,-0.953333,0.520039,0.00881794,0.468412 kka2_1:1_S204Y,kka2_1:1_204,Kka2,kka2_1:1,P00552,,YES,204,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.353,-4.328,2.975,,0.144,E,A,0.27,-1.2,3.022,,65.53,HPO,-0.953333,0.520039,0.00881794,0.491734 kka2_1:1_S251A,kka2_1:1_251,Kka2,kka2_1:1,P00552,,YES,251,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.636,-2.138,-0.498,,0.712,H,A,0.27,-0.25,1.356,,71.59,APP,-2.09367,0.520039,0.0138916,1.0306 kka2_1:1_S251Q,kka2_1:1_251,Kka2,kka2_1:1,P00552,,YES,251,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.636,-2.668,0.032,,0.712,H,A,0.27,-0.25,1.356,,71.59,APP,-2.09367,0.520039,0.0138916,0.959587 kka2_1:1_S32D,kka2_1:1_32,Kka2,kka2_1:1,P00552,,YES,32,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-0.804,-3.272,2.468,,0.768,S,b,0.27,3.75,,,,OPA,-1.74533,0.520039,0.00149998,0.431859 kka2_1:1_S32W,kka2_1:1_32,Kka2,kka2_1:1,P00552,,YES,32,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-0.804,-5.351,4.547,,0.768,S,b,0.27,3.75,,,,OPA,-1.74533,0.520039,0.00149998,0.46636 kka2_1:1_S40F,kka2_1:1_40,Kka2,kka2_1:1,P00552,,YES,40,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.645,-4.453,1.808,,0.32,E,B,0.27,-0.9,25.997,25.997,71.59,HPH,-1.91567,0.520039,0.00693477,0.763764 kka2_1:1_S54A,kka2_1:1_54,Kka2,kka2_1:1,P00552,,YES,54,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.471,-1.705,-0.766,,0.408,S,b,0.27,1.01,6.085,,71.59,HPO,-2.259,0.520039,0.00782867,0.958843 kka2_1:1_S54D,kka2_1:1_54,Kka2,kka2_1:1,P00552,,YES,54,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.471,-2.887,0.416,,0.408,S,b,0.27,1.01,6.085,,71.59,HPO,-2.259,0.520039,0.00782867,0.759568 kka2_1:1_S54E,kka2_1:1_54,Kka2,kka2_1:1,P00552,,YES,54,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.471,-3.63,1.159,,0.408,S,b,0.27,1.01,6.085,,71.59,HPO,-2.259,0.520039,0.00782867,0.759215 kka2_1:1_S54F,kka2_1:1_54,Kka2,kka2_1:1,P00552,,YES,54,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.471,-4.27,1.799,,0.408,S,b,0.27,1.01,6.085,,71.59,HPO,-2.259,0.520039,0.00782867,0.777753 kka2_1:1_S54H,kka2_1:1_54,Kka2,kka2_1:1,P00552,,YES,54,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.471,-3.515,1.044,,0.408,S,b,0.27,1.01,6.085,,71.59,HPO,-2.259,0.520039,0.00782867,0.800914 kka2_1:1_S54L,kka2_1:1_54,Kka2,kka2_1:1,P00552,,YES,54,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.471,-2.689,0.218,,0.408,S,b,0.27,1.01,6.085,,71.59,HPO,-2.259,0.520039,0.00782867,0.815545 kka2_1:1_S54P,kka2_1:1_54,Kka2,kka2_1:1,P00552,,YES,54,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.471,-4.062,1.591,,0.408,S,b,0.27,1.01,6.085,,71.59,HPO,-2.259,0.520039,0.00782867,0.684043 kka2_1:1_S54Q,kka2_1:1_54,Kka2,kka2_1:1,P00552,,YES,54,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.471,-3.041,0.57,,0.408,S,b,0.27,1.01,6.085,,71.59,HPO,-2.259,0.520039,0.00782867,0.809442 kka2_1:1_S54V,kka2_1:1_54,Kka2,kka2_1:1,P00552,,YES,54,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.471,-2.309,-0.162,,0.408,S,b,0.27,1.01,6.085,,71.59,HPO,-2.259,0.520039,0.00782867,0.889734 kka2_1:1_S68A,kka2_1:1_68,Kka2,kka2_1:1,P00552,,YES,68,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.623,-3.303,0.68,,0.48,H,A,0.27,-0.1,2.655,,71.59,HPH,-1.40767,0.520039,0.00608265,0.785836 kka2_1:1_S68D,kka2_1:1_68,Kka2,kka2_1:1,P00552,,YES,68,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.623,-2.48,-0.143,,0.48,H,A,0.27,-0.1,2.655,,71.59,HPH,-1.40767,0.520039,0.00608265,0.811962 kka2_1:1_S68E,kka2_1:1_68,Kka2,kka2_1:1,P00552,,YES,68,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.623,-2.442,-0.181,,0.48,H,A,0.27,-0.1,2.655,,71.59,HPH,-1.40767,0.520039,0.00608265,0.834022 kka2_1:1_S68H,kka2_1:1_68,Kka2,kka2_1:1,P00552,,YES,68,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.623,-3.15,0.527,,0.48,H,A,0.27,-0.1,2.655,,71.59,HPH,-1.40767,0.520039,0.00608265,0.804314 kka2_1:1_S68K,kka2_1:1_68,Kka2,kka2_1:1,P00552,,YES,68,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.623,-2.899,0.276,,0.48,H,A,0.27,-0.1,2.655,,71.59,HPH,-1.40767,0.520039,0.00608265,0.809866 kka2_1:1_S68L,kka2_1:1_68,Kka2,kka2_1:1,P00552,,YES,68,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.623,-2.822,0.199,,0.48,H,A,0.27,-0.1,2.655,,71.59,HPH,-1.40767,0.520039,0.00608265,0.799955 kka2_1:1_S68M,kka2_1:1_68,Kka2,kka2_1:1,P00552,,YES,68,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.623,-4.761,2.138,,0.48,H,A,0.27,-0.1,2.655,,71.59,HPH,-1.40767,0.520039,0.00608265,0.843126 kka2_1:1_S68P,kka2_1:1_68,Kka2,kka2_1:1,P00552,,YES,68,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.623,-4.076,1.453,,0.48,H,A,0.27,-0.1,2.655,,71.59,HPH,-1.40767,0.520039,0.00608265,0.662158 kka2_1:1_S68Q,kka2_1:1_68,Kka2,kka2_1:1,P00552,,YES,68,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.623,-2.944,0.321,,0.48,H,A,0.27,-0.1,2.655,,71.59,HPH,-1.40767,0.520039,0.00608265,0.810732 kka2_1:1_S68V,kka2_1:1_68,Kka2,kka2_1:1,P00552,,YES,68,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.623,-3.127,0.504,,0.48,H,A,0.27,-0.1,2.655,,71.59,HPH,-1.40767,0.520039,0.00608265,0.775478 kka2_1:1_S68W,kka2_1:1_68,Kka2,kka2_1:1,P00552,,YES,68,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.623,-5.546,2.923,,0.48,H,A,0.27,-0.1,2.655,,71.59,HPH,-1.40767,0.520039,0.00608265,0.798729 kka2_1:1_S68Y,kka2_1:1_68,Kka2,kka2_1:1,P00552,,YES,68,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.623,-4.344,1.721,,0.48,H,A,0.27,-0.1,2.655,,71.59,HPH,-1.40767,0.520039,0.00608265,0.738151 kka2_1:1_T125D,kka2_1:1_125,Kka2,kka2_1:1,P00552,,YES,125,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.622,-2.647,0.025,,0.791,T,A,0.22,0.33,1.972,,92.05,BPH,-1.56933,0.520039,0.00821755,0.858069 kka2_1:1_T125E,kka2_1:1_125,Kka2,kka2_1:1,P00552,,YES,125,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.622,-2.741,0.119,,0.791,T,A,0.22,0.33,1.972,,92.05,BPH,-1.56933,0.520039,0.00821755,0.837974 kka2_1:1_T125H,kka2_1:1_125,Kka2,kka2_1:1,P00552,,YES,125,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.622,-4.735,2.113,,0.791,T,A,0.22,0.33,1.972,,92.05,BPH,-1.56933,0.520039,0.00821755,0.897403 kka2_1:1_T125Q,kka2_1:1_125,Kka2,kka2_1:1,P00552,,YES,125,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.622,-2.465,-0.157,,0.791,T,A,0.22,0.33,1.972,,92.05,BPH,-1.56933,0.520039,0.00821755,0.878698 kka2_1:1_T125R,kka2_1:1_125,Kka2,kka2_1:1,P00552,,YES,125,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.622,-2.191,-0.431,,0.791,T,A,0.22,0.33,1.972,,92.05,BPH,-1.56933,0.520039,0.00821755,0.936036 kka2_1:1_T125W,kka2_1:1_125,Kka2,kka2_1:1,P00552,,YES,125,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.622,-5.542,2.92,,0.791,T,A,0.22,0.33,1.972,,92.05,BPH,-1.56933,0.520039,0.00821755,0.837276 kka2_1:1_T130D,kka2_1:1_130,Kka2,kka2_1:1,P00552,,YES,130,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.392,-2.708,0.316,,0.561,G,A,0.22,0.77,0.5,,92.05,HPO,-1.62633,0.520039,0.00804204,0.756199 kka2_1:1_T130E,kka2_1:1_130,Kka2,kka2_1:1,P00552,,YES,130,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.392,-3.049,0.657,,0.561,G,A,0.22,0.77,0.5,,92.05,HPO,-1.62633,0.520039,0.00804204,0.75102 kka2_1:1_T130F,kka2_1:1_130,Kka2,kka2_1:1,P00552,,YES,130,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.392,-4.384,1.992,,0.561,G,A,0.22,0.77,0.5,,92.05,HPO,-1.62633,0.520039,0.00804204,0.822142 kka2_1:1_T130G,kka2_1:1_130,Kka2,kka2_1:1,P00552,,YES,130,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.392,-2.278,-0.114,,0.561,G,A,0.22,0.77,0.5,,92.05,HPO,-1.62633,0.520039,0.00804204,0.820913 kka2_1:1_T130L,kka2_1:1_130,Kka2,kka2_1:1,P00552,,YES,130,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.392,-2.848,0.456,,0.561,G,A,0.22,0.77,0.5,,92.05,HPO,-1.62633,0.520039,0.00804204,0.76272 kka2_1:1_T130Q,kka2_1:1_130,Kka2,kka2_1:1,P00552,,YES,130,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.392,-3.316,0.924,,0.561,G,A,0.22,0.77,0.5,,92.05,HPO,-1.62633,0.520039,0.00804204,0.794363 kka2_1:1_T130R,kka2_1:1_130,Kka2,kka2_1:1,P00552,,YES,130,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.392,-3.981,1.589,,0.561,G,A,0.22,0.77,0.5,,92.05,HPO,-1.62633,0.520039,0.00804204,0.778973 kka2_1:1_T130V,kka2_1:1_130,Kka2,kka2_1:1,P00552,,YES,130,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.392,-3.647,1.255,,0.561,G,A,0.22,0.77,0.5,,92.05,HPO,-1.62633,0.520039,0.00804204,0.771853 kka2_1:1_T130Y,kka2_1:1_130,Kka2,kka2_1:1,P00552,,YES,130,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.392,-4.42,2.028,,0.561,G,A,0.22,0.77,0.5,,92.05,HPO,-1.62633,0.520039,0.00804204,0.826473 kka2_1:1_T146E,kka2_1:1_146,Kka2,kka2_1:1,P00552,,YES,146,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.978,-2.468,-0.51,,0.281,H,A,0.82,0.78,2.105,,92.05,BPB,-1.96833,0.520039,0.00606474,0.900478 kka2_1:1_T146G,kka2_1:1_146,Kka2,kka2_1:1,P00552,,YES,146,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.978,-3.466,0.488,,0.281,H,A,0.82,0.78,2.105,,92.05,BPB,-1.96833,0.520039,0.00606474,0.731639 kka2_1:1_T146H,kka2_1:1_146,Kka2,kka2_1:1,P00552,,YES,146,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.978,-4.762,1.784,,0.281,H,A,0.82,0.78,2.105,,92.05,BPB,-1.96833,0.520039,0.00606474,0.736143 kka2_1:1_T146L,kka2_1:1_146,Kka2,kka2_1:1,P00552,,YES,146,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.978,-2.714,-0.264,,0.281,H,A,0.82,0.78,2.105,,92.05,BPB,-1.96833,0.520039,0.00606474,0.843632 kka2_1:1_T146V,kka2_1:1_146,Kka2,kka2_1:1,P00552,,YES,146,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.978,-2.951,-0.027,,0.281,H,A,0.82,0.78,2.105,,92.05,BPB,-1.96833,0.520039,0.00606474,0.814653 kka2_1:1_T225G,kka2_1:1_225,Kka2,kka2_1:1,P00552,,YES,225,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.393,-3.525,1.132,,0.036,H,A,0.22,-1.22,4.554,,63.64,HPB,-1.58733,0.520039,0.0113598,0.481222 kka2_1:1_T28H,kka2_1:1_28,Kka2,kka2_1:1,P00552,,YES,28,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.883,-3.548,1.665,,0.353,S,B,0.22,2.02,1.12,,63.64,PPH,-1.74467,0.520039,0.00743084,0.621208 kka2_1:1_T28L,kka2_1:1_28,Kka2,kka2_1:1,P00552,,YES,28,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.883,-2.972,1.089,,0.353,S,B,0.22,2.02,1.12,,63.64,PPH,-1.74467,0.520039,0.00743084,0.655233 kka2_1:1_T28P,kka2_1:1_28,Kka2,kka2_1:1,P00552,,YES,28,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.883,-3.202,1.319,,0.353,S,B,0.22,2.02,1.12,,63.64,PPH,-1.74467,0.520039,0.00743084,0.592897 kka2_1:1_T28V,kka2_1:1_28,Kka2,kka2_1:1,P00552,,YES,28,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.883,-2.663,0.78,,0.353,S,B,0.22,2.02,1.12,,63.64,PPH,-1.74467,0.520039,0.00743084,0.68183 kka2_1:1_T51G,kka2_1:1_51,Kka2,kka2_1:1,P00552,,YES,51,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.199,-2.948,0.749,,0.05,E,B,0.22,-0.05,3.056,,63.64,BPA,-1.76767,0.520039,0.00628861,0.558519 kka2_1:1_T51L,kka2_1:1_51,Kka2,kka2_1:1,P00552,,YES,51,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.199,-2.881,0.682,,0.05,E,B,0.22,-0.05,3.056,,63.64,BPA,-1.76767,0.520039,0.00628861,0.568936 kka2_1:1_T51P,kka2_1:1_51,Kka2,kka2_1:1,P00552,,YES,51,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.199,-4.078,1.879,,0.05,E,B,0.22,-0.05,3.056,,63.64,BPA,-1.76767,0.520039,0.00628861,0.449781 kka2_1:1_T51R,kka2_1:1_51,Kka2,kka2_1:1,P00552,,YES,51,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.199,-3.007,0.808,,0.05,E,B,0.22,-0.05,3.056,,63.64,BPA,-1.76767,0.520039,0.00628861,0.538104 kka2_1:1_T51V,kka2_1:1_51,Kka2,kka2_1:1,P00552,,YES,51,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.199,-2.337,0.138,,0.05,E,B,0.22,-0.05,3.056,,63.64,BPA,-1.76767,0.520039,0.00628861,0.652437 kka2_1:1_T51W,kka2_1:1_51,Kka2,kka2_1:1,P00552,,YES,51,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.199,-5.512,3.313,,0.05,E,B,0.22,-0.05,3.056,,63.64,BPA,-1.76767,0.520039,0.00628861,0.546323 kka2_1:1_T72C,kka2_1:1_72,Kka2,kka2_1:1,P00552,,YES,72,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.38,-5.141,2.761,,0.784,H,A,0.22,0.29,10.43,10.43,65.53,HPP,-2.238,0.520039,0.00750756,0.772567 kka2_1:1_T72G,kka2_1:1_72,Kka2,kka2_1:1,P00552,,YES,72,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.38,-2.12,-0.26,,0.784,H,A,0.22,0.29,10.43,10.43,65.53,HPP,-2.238,0.520039,0.00750756,0.900053 kka2_1:1_T72R,kka2_1:1_72,Kka2,kka2_1:1,P00552,,YES,72,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.38,-2.467,0.087,,0.784,H,A,0.22,0.29,10.43,10.43,65.53,HPP,-2.238,0.520039,0.00750756,0.882317 kka2_1:1_T72S,kka2_1:1_72,Kka2,kka2_1:1,P00552,,YES,72,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.38,-2.339,-0.041,,0.784,H,A,0.22,0.29,10.43,10.43,65.53,HPP,-2.238,0.520039,0.00750756,0.887108 kka2_1:1_T85D,kka2_1:1_85,Kka2,kka2_1:1,P00552,,YES,85,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.165,-2.694,0.529,,0.576,E,B,0.82,1.39,16.653,16.653,71.59,HPA,-2.10133,0.520039,0.00634493,0.789081 kka2_1:1_T85F,kka2_1:1_85,Kka2,kka2_1:1,P00552,,YES,85,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.165,-3.388,1.223,,0.576,E,B,0.82,1.39,16.653,16.653,71.59,HPA,-2.10133,0.520039,0.00634493,0.800339 kka2_1:1_T85G,kka2_1:1_85,Kka2,kka2_1:1,P00552,,YES,85,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.165,-3.601,1.436,,0.576,E,B,0.82,1.39,16.653,16.653,71.59,HPA,-2.10133,0.520039,0.00634493,0.777879 kka2_1:1_T85H,kka2_1:1_85,Kka2,kka2_1:1,P00552,,YES,85,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.165,-3.24,1.075,,0.576,E,B,0.82,1.39,16.653,16.653,71.59,HPA,-2.10133,0.520039,0.00634493,0.815691 kka2_1:1_T85K,kka2_1:1_85,Kka2,kka2_1:1,P00552,,YES,85,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.165,-3.032,0.867,,0.576,E,B,0.82,1.39,16.653,16.653,71.59,HPA,-2.10133,0.520039,0.00634493,0.820153 kka2_1:1_T85Q,kka2_1:1_85,Kka2,kka2_1:1,P00552,,YES,85,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.165,-2.53,0.365,,0.576,E,B,0.82,1.39,16.653,16.653,71.59,HPA,-2.10133,0.520039,0.00634493,0.839123 kka2_1:1_T85V,kka2_1:1_85,Kka2,kka2_1:1,P00552,,YES,85,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.165,-2.678,0.513,,0.576,E,B,0.82,1.39,16.653,16.653,71.59,HPA,-2.10133,0.520039,0.00634493,0.77113 kka2_1:1_T85W,kka2_1:1_85,Kka2,kka2_1:1,P00552,,YES,85,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.165,-5.494,3.329,,0.576,E,B,0.82,1.39,16.653,16.653,71.59,HPA,-2.10133,0.520039,0.00634493,0.76806 kka2_1:1_T85Y,kka2_1:1_85,Kka2,kka2_1:1,P00552,,YES,85,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.165,-4.263,2.098,,0.576,E,B,0.82,1.39,16.653,16.653,71.59,HPA,-2.10133,0.520039,0.00634493,0.789333 kka2_1:1_V113F,kka2_1:1_113,Kka2,kka2_1:1,P00552,,YES,113,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.233,-3.907,2.674,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.520039,0.00650191,0.38936 kka2_1:1_V113S,kka2_1:1_113,Kka2,kka2_1:1,P00552,,YES,113,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.233,-3.696,2.463,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.520039,0.00650191,0.439132 kka2_1:1_V153T,kka2_1:1_153,Kka2,kka2_1:1,P00552,,YES,153,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.092,-3.365,2.273,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.520039,0.00501119,0.521741 kka2_1:1_V153Y,kka2_1:1_153,Kka2,kka2_1:1,P00552,,YES,153,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.092,-4.06,2.968,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.520039,0.00501119,0.45802 kka2_1:1_V16C,kka2_1:1_16,Kka2,kka2_1:1,P00552,,YES,16,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-3.087,-3.613,0.526,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.520039,0.00694011,0.841825 kka2_1:1_V16K,kka2_1:1_16,Kka2,kka2_1:1,P00552,,YES,16,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-3.087,-2.781,-0.306,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.520039,0.00694011,0.903515 kka2_1:1_V16N,kka2_1:1_16,Kka2,kka2_1:1,P00552,,YES,16,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-3.087,-3.138,0.051,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.520039,0.00694011,0.860781 kka2_1:1_V16R,kka2_1:1_16,Kka2,kka2_1:1,P00552,,YES,16,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-3.087,-1.961,-1.126,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.520039,0.00694011,0.963996 kka2_1:1_V16T,kka2_1:1_16,Kka2,kka2_1:1,P00552,,YES,16,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-3.087,-3.05,-0.037,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.520039,0.00694011,0.857264 kka2_1:1_V16Y,kka2_1:1_16,Kka2,kka2_1:1,P00552,,YES,16,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-3.087,-4.365,1.278,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.520039,0.00694011,0.861802 kka2_1:1_V214Q,kka2_1:1_214,Kka2,kka2_1:1,P00552,,YES,214,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.261,-4.289,3.028,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.520039,0.00692782,0.481625 kka2_1:1_V242P,kka2_1:1_242,Kka2,kka2_1:1,P00552,,YES,242,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-2.687,-4.019,1.332,,0.75,H,A,0.44,-0.37,4.987,,71.59,HHH,-2.16533,0.520039,0.0102575,0.850442 kka2_1:1_V242Y,kka2_1:1_242,Kka2,kka2_1:1,P00552,,YES,242,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-2.687,-4.381,1.694,,0.75,H,A,0.44,-0.37,4.987,,71.59,HHH,-2.16533,0.520039,0.0102575,0.991091 kka2_1:1_V36K,kka2_1:1_36,Kka2,kka2_1:1,P00552,,YES,36,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-0.898,-3.793,2.895,,0.292,E,B,0.44,0.21,0.278,,52.27,HHH,-1.484,0.520039,0.00245633,0.411288 kka2_1:1_V46H,kka2_1:1_46,Kka2,kka2_1:1,P00552,,YES,46,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-2.62,-3.614,0.994,,0.192,.,B,0.44,-1.12,20.149,20.149,92.05,OHH,-1.88633,0.520039,0.00631301,0.788321 kka2_1:1_V46Y,kka2_1:1_46,Kka2,kka2_1:1,P00552,,YES,46,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-2.62,-4.392,1.772,,0.192,.,B,0.44,-1.12,20.149,20.149,92.05,OHH,-1.88633,0.520039,0.00631301,0.736647 kka2_1:1_V75Q,kka2_1:1_75,Kka2,kka2_1:1,P00552,,YES,75,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-2.06,-2.734,0.674,,0.042,.,B,0.44,-0.2,2.815,,71.59,OHO,-1.563,0.520039,0.00693733,0.676714 kka2_1:1_V83H,kka2_1:1_83,Kka2,kka2_1:1,P00552,,YES,83,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-2.567,-2.84,0.273,,0.358,E,B,0.44,0.53,5.931,,71.59,AHH,-2.264,0.520039,0.00650486,0.858162 kka2_1:1_V83I,kka2_1:1_83,Kka2,kka2_1:1,P00552,,YES,83,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-2.567,-3.777,1.21,,0.358,E,B,0.44,0.53,5.931,,71.59,AHH,-2.264,0.520039,0.00650486,0.720704 kka2_1:1_V83N,kka2_1:1_83,Kka2,kka2_1:1,P00552,,YES,83,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-2.567,-3.217,0.65,,0.358,E,B,0.44,0.53,5.931,,71.59,AHH,-2.264,0.520039,0.00650486,0.808568 kka2_1:1_V83R,kka2_1:1_83,Kka2,kka2_1:1,P00552,,YES,83,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-2.567,-2.854,0.287,,0.358,E,B,0.44,0.53,5.931,,71.59,AHH,-2.264,0.520039,0.00650486,0.85649 kka2_1:1_V83S,kka2_1:1_83,Kka2,kka2_1:1,P00552,,YES,83,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-2.567,-2.85,0.283,,0.358,E,B,0.44,0.53,5.931,,71.59,AHH,-2.264,0.520039,0.00650486,0.835212 kka2_1:1_V83T,kka2_1:1_83,Kka2,kka2_1:1,P00552,,YES,83,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-2.567,-2.28,-0.287,,0.358,E,B,0.44,0.53,5.931,,71.59,AHH,-2.264,0.520039,0.00650486,0.929538 kka2_1:1_V83W,kka2_1:1_83,Kka2,kka2_1:1,P00552,,YES,83,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-2.567,-5.342,2.775,,0.358,E,B,0.44,0.53,5.931,,71.59,AHH,-2.264,0.520039,0.00650486,0.776055 kka2_1:1_V84C,kka2_1:1_84,Kka2,kka2_1:1,P00552,,YES,84,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-2.279,-5.009,2.73,,0.258,E,B,0.44,1.03,3.484,,71.59,HHP,-2.337,0.520039,0.00724019,0.858562 kka2_1:1_V84D,kka2_1:1_84,Kka2,kka2_1:1,P00552,,YES,84,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-2.279,-2.613,0.334,,0.258,E,B,0.44,1.03,3.484,,71.59,HHP,-2.337,0.520039,0.00724019,0.764291 kka2_1:1_V84E,kka2_1:1_84,Kka2,kka2_1:1,P00552,,YES,84,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-2.279,-2.088,-0.191,,0.258,E,B,0.44,1.03,3.484,,71.59,HHP,-2.337,0.520039,0.00724019,0.873749 kka2_1:1_V84N,kka2_1:1_84,Kka2,kka2_1:1,P00552,,YES,84,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-2.279,-3.883,1.604,,0.258,E,B,0.44,1.03,3.484,,71.59,HHP,-2.337,0.520039,0.00724019,0.711555 kka2_1:1_V84Q,kka2_1:1_84,Kka2,kka2_1:1,P00552,,YES,84,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-2.279,-3.218,0.939,,0.258,E,B,0.44,1.03,3.484,,71.59,HHP,-2.337,0.520039,0.00724019,0.748333 kka2_1:1_V84R,kka2_1:1_84,Kka2,kka2_1:1,P00552,,YES,84,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-2.279,-3.996,1.717,,0.258,E,B,0.44,1.03,3.484,,71.59,HHP,-2.337,0.520039,0.00724019,0.707303 kka2_1:1_V84T,kka2_1:1_84,Kka2,kka2_1:1,P00552,,YES,84,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-2.279,-2.154,-0.125,,0.258,E,B,0.44,1.03,3.484,,71.59,HHP,-2.337,0.520039,0.00724019,0.892028 kka2_1:1_V84W,kka2_1:1_84,Kka2,kka2_1:1,P00552,,YES,84,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-2.279,-5.522,3.243,,0.258,E,B,0.44,1.03,3.484,,71.59,HHP,-2.337,0.520039,0.00724019,0.757136 kka2_1:1_V84Y,kka2_1:1_84,Kka2,kka2_1:1,P00552,,YES,84,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-2.279,-4.308,2.029,,0.258,E,B,0.44,1.03,3.484,,71.59,HHP,-2.337,0.520039,0.00724019,0.728317 kka2_1:1_V97S,kka2_1:1_97,Kka2,kka2_1:1,P00552,,YES,97,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.453,-3.709,2.256,,0.083,,B,1.48,-0.83,13.576,13.576,53.03,AHO,-1.85067,0.520039,0.00737869,0.460814 kka2_1:1_V97T,kka2_1:1_97,Kka2,kka2_1:1,P00552,,YES,97,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.453,-3.491,2.038,,0.083,,B,1.48,-0.83,13.576,13.576,53.03,AHO,-1.85067,0.520039,0.00737869,0.471383 kka2_1:1_W15A,kka2_1:1_15,Kka2,kka2_1:1,P00552,,YES,15,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-1.392,-3.416,2.024,,0.01,G,A,0.47,0.15,20.149,20.149,52.27,HHH,-2.10533,0.520039,0.00585505,0.493822 kka2_1:1_W15E,kka2_1:1_15,Kka2,kka2_1:1,P00552,,YES,15,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-1.392,-4.005,2.613,,0.01,G,A,0.47,0.15,20.149,20.149,52.27,HHH,-2.10533,0.520039,0.00585505,0.475922 kka2_1:1_W15H,kka2_1:1_15,Kka2,kka2_1:1,P00552,,YES,15,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-1.392,-4.848,3.456,,0.01,G,A,0.47,0.15,20.149,20.149,52.27,HHH,-2.10533,0.520039,0.00585505,0.502798 kka2_1:1_W15I,kka2_1:1_15,Kka2,kka2_1:1,P00552,,YES,15,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-1.392,-2.748,1.356,,0.01,G,A,0.47,0.15,20.149,20.149,52.27,HHH,-2.10533,0.520039,0.00585505,0.619765 kka2_1:1_W236V,kka2_1:1_236,Kka2,kka2_1:1,P00552,,YES,236,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-1.363,-3.56,2.197,,0.303,H,A,1.51,-0.76,12.263,12.263,48.48,AHH,-1.81267,0.520039,0.0088796,0.48773 kka2_1:1_W24K,kka2_1:1_24,Kka2,kka2_1:1,P00552,,YES,24,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-1.779,-4.012,2.233,,0.477,E,B,0.47,-0.21,2.375,,56.06,AHH,-2.24467,0.520039,0.00631564,0.46459 kka2_1:1_W69A,kka2_1:1_69,Kka2,kka2_1:1,P00552,,YES,69,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-0.859,-3.554,2.695,,0.164,H,A,0.47,0.15,5.074,,38.64,PHH,-1.49967,0.520039,0.0012874,0.434849 kka2_1:1_W69E,kka2_1:1_69,Kka2,kka2_1:1,P00552,,YES,69,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-0.859,-3.916,3.057,,0.164,H,A,0.47,0.15,5.074,,38.64,PHH,-1.49967,0.520039,0.0012874,0.398961 kka2_1:1_W69I,kka2_1:1_69,Kka2,kka2_1:1,P00552,,YES,69,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-0.859,-4.006,3.147,,0.164,H,A,0.47,0.15,5.074,,38.64,PHH,-1.49967,0.520039,0.0012874,0.381573 kka2_1:1_W69K,kka2_1:1_69,Kka2,kka2_1:1,P00552,,YES,69,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-0.859,-3.933,3.074,,0.164,H,A,0.47,0.15,5.074,,38.64,PHH,-1.49967,0.520039,0.0012874,0.397653 kka2_1:1_W69S,kka2_1:1_69,Kka2,kka2_1:1,P00552,,YES,69,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-0.859,-3.862,3.003,,0.164,H,A,0.47,0.15,5.074,,38.64,PHH,-1.49967,0.520039,0.0012874,0.45155 kka2_1:1_W91K,kka2_1:1_91,Kka2,kka2_1:1,P00552,,YES,91,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-1.178,-3.72,2.542,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.520039,0.00358653,0.482402 kka2_1:1_W91T,kka2_1:1_91,Kka2,kka2_1:1,P00552,,YES,91,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-1.178,-3.718,2.54,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.520039,0.00358653,0.534507 kka2_1:1_Y218A,kka2_1:1_218,Kka2,kka2_1:1,P00552,,YES,218,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-1.438,-2.767,1.329,,0.122,H,A,1.25,-0.69,3.059,,56.06,BHP,-1.17533,0.520039,0.0126098,0.50698 kka2_1:1_Y218Q,kka2_1:1_218,Kka2,kka2_1:1,P00552,,YES,218,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-1.438,-4.079,2.641,,0.122,H,A,1.25,-0.69,3.059,,56.06,BHP,-1.17533,0.520039,0.0126098,0.445195 kka2_1:1_Y22A,kka2_1:1_22,Kka2,kka2_1:1,P00552,,YES,22,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-1.583,-1.97,0.387,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.520039,0.00598977,0.628941 kka2_1:1_Y22T,kka2_1:1_22,Kka2,kka2_1:1,P00552,,YES,22,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-1.583,-2.95,1.367,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.520039,0.00598977,0.566546 kka2_1:1_Y22V,kka2_1:1_22,Kka2,kka2_1:1,P00552,,YES,22,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-1.583,-3.487,1.904,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.520039,0.00598977,0.486507 kka2_1:2_A108K,kka2_1:2_108,Kka2,kka2_1:2,P00552,,YES,108,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.061,-3.668,1.607,,0.243,.,B,0.46,-1.34,2.462,,71.59,HHO,-1.57033,0.295029,0.00751209,0.601303 kka2_1:2_A110C,kka2_1:2_110,Kka2,kka2_1:2,P00552,,YES,110,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.064,-5.167,3.103,,0.175,H,A,0.46,-1.19,23.237,23.237,71.59,OHA,-1.91867,0.295029,0.00759851,0.77008 kka2_1:2_A117I,kka2_1:2_117,Kka2,kka2_1:2,P00552,,YES,117,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.828,-3.432,2.604,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.295029,0.00282984,0.39758 kka2_1:2_A119F,kka2_1:2_119,Kka2,kka2_1:2,P00552,,YES,119,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.073,-4.171,3.098,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.295029,0.00441074,0.436957 kka2_1:2_A119H,kka2_1:2_119,Kka2,kka2_1:2,P00552,,YES,119,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.073,-4.774,3.701,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.295029,0.00441074,0.472881 kka2_1:2_A119I,kka2_1:2_119,Kka2,kka2_1:2,P00552,,YES,119,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.073,-3.591,2.518,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.295029,0.00441074,0.42637 kka2_1:2_A119N,kka2_1:2_119,Kka2,kka2_1:2,P00552,,YES,119,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.073,-3.831,2.758,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.295029,0.00441074,0.426048 kka2_1:2_A129C,kka2_1:2_129,Kka2,kka2_1:2,P00552,,YES,129,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.656,-5.053,3.397,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.295029,0.00726862,0.80658 kka2_1:2_A129F,kka2_1:2_129,Kka2,kka2_1:2,P00552,,YES,129,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.656,-4.391,2.735,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.295029,0.00726862,0.796528 kka2_1:2_A129H,kka2_1:2_129,Kka2,kka2_1:2,P00552,,YES,129,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.656,-3.201,1.545,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.295029,0.00726862,0.762131 kka2_1:2_A129K,kka2_1:2_129,Kka2,kka2_1:2,P00552,,YES,129,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.656,-3.023,1.367,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.295029,0.00726862,0.765339 kka2_1:2_A129N,kka2_1:2_129,Kka2,kka2_1:2,P00552,,YES,129,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.656,-2.9,1.244,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.295029,0.00726862,0.766948 kka2_1:2_A129R,kka2_1:2_129,Kka2,kka2_1:2,P00552,,YES,129,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.656,-2.972,1.316,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.295029,0.00726862,0.771802 kka2_1:2_A129Y,kka2_1:2_129,Kka2,kka2_1:2,P00552,,YES,129,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.656,-4.374,2.718,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.295029,0.00726862,0.795545 kka2_1:2_A13H,kka2_1:2_13,Kka2,kka2_1:2,P00552,,YES,13,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.248,-3.721,1.473,,0.689,G,A,0.46,0.99,,,92.05,OHH,-1.646,0.295029,0.00784241,0.887622 kka2_1:2_A13K,kka2_1:2_13,Kka2,kka2_1:2,P00552,,YES,13,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.248,-3.012,0.764,,0.689,G,A,0.46,0.99,,,92.05,OHH,-1.646,0.295029,0.00784241,0.889009 kka2_1:2_A13L,kka2_1:2_13,Kka2,kka2_1:2,P00552,,YES,13,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.248,-2.945,0.697,,0.689,G,A,0.46,0.99,,,92.05,OHH,-1.646,0.295029,0.00784241,0.880535 kka2_1:2_A13N,kka2_1:2_13,Kka2,kka2_1:2,P00552,,YES,13,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.248,-3.116,0.868,,0.689,G,A,0.46,0.99,,,92.05,OHH,-1.646,0.295029,0.00784241,0.917178 kka2_1:2_A13Y,kka2_1:2_13,Kka2,kka2_1:2,P00552,,YES,13,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.248,-4.443,2.195,,0.689,G,A,0.46,0.99,,,92.05,OHH,-1.646,0.295029,0.00784241,0.935934 kka2_1:2_A144I,kka2_1:2_144,Kka2,kka2_1:2,P00552,,YES,144,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.859,-3.396,2.537,,,H,A,0.46,0.21,6.844,,52.65,BHB,-1.72933,0.295029,0.00231095,0.396053 kka2_1:2_A144P,kka2_1:2_144,Kka2,kka2_1:2,P00552,,YES,144,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.859,-3.765,2.906,,,H,A,0.46,0.21,6.844,,52.65,BHB,-1.72933,0.295029,0.00231095,0.448647 kka2_1:2_A14C,kka2_1:2_14,Kka2,kka2_1:2,P00552,,YES,14,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.837,-5.018,3.181,,0.728,G,A,0.46,0.7,0.36,,71.59,HHH,-1.82567,0.295029,0.00706614,0.792859 kka2_1:2_A14F,kka2_1:2_14,Kka2,kka2_1:2,P00552,,YES,14,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.837,-4.392,2.555,,0.728,G,A,0.46,0.7,0.36,,71.59,HHH,-1.82567,0.295029,0.00706614,0.772336 kka2_1:2_A14N,kka2_1:2_14,Kka2,kka2_1:2,P00552,,YES,14,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.837,-3.807,1.97,,0.728,G,A,0.46,0.7,0.36,,71.59,HHH,-1.82567,0.295029,0.00706614,0.774269 kka2_1:2_A14R,kka2_1:2_14,Kka2,kka2_1:2,P00552,,YES,14,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.837,-2.714,0.877,,0.728,G,A,0.46,0.7,0.36,,71.59,HHH,-1.82567,0.295029,0.00706614,0.79626 kka2_1:2_A150C,kka2_1:2_150,Kka2,kka2_1:2,P00552,,YES,150,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.949,-4.673,3.724,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.295029,0.0045009,0.713745 kka2_1:2_A150Y,kka2_1:2_150,Kka2,kka2_1:2,P00552,,YES,150,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.949,-4.269,3.32,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.295029,0.0045009,0.622011 kka2_1:2_A168I,kka2_1:2_168,Kka2,kka2_1:2,P00552,,YES,168,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.989,-4.068,2.079,,0.67,H,A,0.46,0.15,25.546,25.546,64.39,OHA,-2.12933,0.295029,0.00806773,0.762586 kka2_1:2_A224C,kka2_1:2_224,Kka2,kka2_1:2,P00552,,YES,224,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.977,-4.591,3.614,,,H,A,0.46,-1.26,1.646,,63.64,HHP,-1.41033,0.295029,0.00352047,0.505498 kka2_1:2_A224I,kka2_1:2_224,Kka2,kka2_1:2,P00552,,YES,224,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.977,-3.567,2.59,,,H,A,0.46,-1.26,1.646,,63.64,HHP,-1.41033,0.295029,0.00352047,0.391142 kka2_1:2_A237F,kka2_1:2_237,Kka2,kka2_1:2,P00552,,YES,237,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.12,-4.013,1.893,,0.068,H,A,0.46,-0.71,2.369,,92.05,HHA,-2.10433,0.295029,0.012257,0.45233 kka2_1:2_A237H,kka2_1:2_237,Kka2,kka2_1:2,P00552,,YES,237,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.12,-4.997,2.877,,0.068,H,A,0.46,-0.71,2.369,,92.05,HHA,-2.10433,0.295029,0.012257,0.539234 kka2_1:2_A237Y,kka2_1:2_237,Kka2,kka2_1:2,P00552,,YES,237,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.12,-4.178,2.058,,0.068,H,A,0.46,-0.71,2.369,,92.05,HHA,-2.10433,0.295029,0.012257,0.467865 kka2_1:2_A247F,kka2_1:2_247,Kka2,kka2_1:2,P00552,,YES,247,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.459,-3.316,0.857,,1.01,S,A,0.46,0.65,0.828,,92.05,HHH,-2.197,0.295029,0.0102428,0.85103 kka2_1:2_A247H,kka2_1:2_247,Kka2,kka2_1:2,P00552,,YES,247,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.459,-3.473,1.014,,1.01,S,A,0.46,0.65,0.828,,92.05,HHH,-2.197,0.295029,0.0102428,0.880347 kka2_1:2_A248C,kka2_1:2_248,Kka2,kka2_1:2,P00552,,YES,248,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.124,-5.173,3.049,,0.825,S,b,0.46,0.46,,,92.05,HHO,-2.15,0.295029,0.0125484,0.849687 kka2_1:2_A248F,kka2_1:2_248,Kka2,kka2_1:2,P00552,,YES,248,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.124,-4.425,2.301,,0.825,S,b,0.46,0.46,,,92.05,HHO,-2.15,0.295029,0.0125484,0.865827 kka2_1:2_A248H,kka2_1:2_248,Kka2,kka2_1:2,P00552,,YES,248,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.124,-3.589,1.465,,0.825,S,b,0.46,0.46,,,92.05,HHO,-2.15,0.295029,0.0125484,0.868344 kka2_1:2_A248I,kka2_1:2_248,Kka2,kka2_1:2,P00552,,YES,248,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.124,-3.04,0.916,,0.825,S,b,0.46,0.46,,,92.05,HHO,-2.15,0.295029,0.0125484,0.836627 kka2_1:2_A248N,kka2_1:2_248,Kka2,kka2_1:2,P00552,,YES,248,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.124,-3.883,1.759,,0.825,S,b,0.46,0.46,,,92.05,HHO,-2.15,0.295029,0.0125484,0.831335 kka2_1:2_A248Q,kka2_1:2_248,Kka2,kka2_1:2,P00552,,YES,248,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.124,-2.728,0.604,,0.825,S,b,0.46,0.46,,,92.05,HHO,-2.15,0.295029,0.0125484,0.863399 kka2_1:2_A248Y,kka2_1:2_248,Kka2,kka2_1:2,P00552,,YES,248,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.124,-4.406,2.282,,0.825,S,b,0.46,0.46,,,92.05,HHO,-2.15,0.295029,0.0125484,0.879879 kka2_1:2_A25I,kka2_1:2_25,Kka2,kka2_1:2,P00552,,YES,25,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.496,-3.984,1.488,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.295029,0.00595636,0.606972 kka2_1:2_A25K,kka2_1:2_25,Kka2,kka2_1:2,P00552,,YES,25,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.496,-2.905,0.409,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.295029,0.00595636,0.766922 kka2_1:2_A25Y,kka2_1:2_25,Kka2,kka2_1:2,P00552,,YES,25,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.496,-4.311,1.815,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.295029,0.00595636,0.647616 kka2_1:2_A34H,kka2_1:2_34,Kka2,kka2_1:2,P00552,,YES,34,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.928,-4.681,3.753,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.295029,0.00343484,0.464809 kka2_1:2_A34I,kka2_1:2_34,Kka2,kka2_1:2,P00552,,YES,34,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.928,-3.671,2.743,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.295029,0.00343484,0.435225 kka2_1:2_A34K,kka2_1:2_34,Kka2,kka2_1:2,P00552,,YES,34,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.928,-3.458,2.53,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.295029,0.00343484,0.479066 kka2_1:2_A34N,kka2_1:2_34,Kka2,kka2_1:2,P00552,,YES,34,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.928,-3.748,2.82,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.295029,0.00343484,0.436696 kka2_1:2_A35F,kka2_1:2_35,Kka2,kka2_1:2,P00552,,YES,35,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.127,-4.402,2.275,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.295029,0.00630016,0.653172 kka2_1:2_A35H,kka2_1:2_35,Kka2,kka2_1:2,P00552,,YES,35,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.127,-3.517,1.39,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.295029,0.00630016,0.674501 kka2_1:2_A35I,kka2_1:2_35,Kka2,kka2_1:2,P00552,,YES,35,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.127,-4.036,1.909,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.295029,0.00630016,0.653329 kka2_1:2_A35N,kka2_1:2_35,Kka2,kka2_1:2,P00552,,YES,35,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.127,-2.713,0.586,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.295029,0.00630016,0.762294 kka2_1:2_A35R,kka2_1:2_35,Kka2,kka2_1:2,P00552,,YES,35,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.127,-3.236,1.109,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.295029,0.00630016,0.695955 kka2_1:2_A35Y,kka2_1:2_35,Kka2,kka2_1:2,P00552,,YES,35,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.127,-4.416,2.289,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.295029,0.00630016,0.66253 kka2_1:2_A41K,kka2_1:2_41,Kka2,kka2_1:2,P00552,,YES,41,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.879,-3.682,1.803,,0.184,.,B,0.46,-0.96,24.451,24.451,64.39,PHP,-2.477,0.295029,0.00543332,0.577081 kka2_1:2_A56K,kka2_1:2_56,Kka2,kka2_1:2,P00552,,YES,56,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.083,-3.671,1.588,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.295029,0.00717715,0.814696 kka2_1:2_A56Y,kka2_1:2_56,Kka2,kka2_1:2,P00552,,YES,56,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.083,-4.486,2.403,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.295029,0.00717715,0.875056 kka2_1:2_A64F,kka2_1:2_64,Kka2,kka2_1:2,P00552,,YES,64,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.496,-4.09,2.594,,0.039,H,A,0.46,-0.57,14.509,14.509,56.06,AHH,-1.334,0.295029,0.00705578,0.490058 kka2_1:2_A64I,kka2_1:2_64,Kka2,kka2_1:2,P00552,,YES,64,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.496,-1.939,0.443,,0.039,H,A,0.46,-0.57,14.509,14.509,56.06,AHH,-1.334,0.295029,0.00705578,0.687446 kka2_1:2_A64Q,kka2_1:2_64,Kka2,kka2_1:2,P00552,,YES,64,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.496,-4.195,2.699,,0.039,H,A,0.46,-0.57,14.509,14.509,56.06,AHH,-1.334,0.295029,0.00705578,0.506764 kka2_1:2_A64W,kka2_1:2_64,Kka2,kka2_1:2,P00552,,YES,64,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.496,-5.479,3.983,,0.039,H,A,0.46,-0.57,14.509,14.509,56.06,AHH,-1.334,0.295029,0.00705578,0.479617 kka2_1:2_A65D,kka2_1:2_65,Kka2,kka2_1:2,P00552,,YES,65,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.744,-2.659,0.915,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.295029,0.00709258,0.657591 kka2_1:2_A65H,kka2_1:2_65,Kka2,kka2_1:2,P00552,,YES,65,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.744,-3.525,1.781,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.295029,0.00709258,0.64958 kka2_1:2_A65I,kka2_1:2_65,Kka2,kka2_1:2,P00552,,YES,65,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.744,-3.823,2.079,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.295029,0.00709258,0.61965 kka2_1:2_A65N,kka2_1:2_65,Kka2,kka2_1:2,P00552,,YES,65,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.744,-3.167,1.423,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.295029,0.00709258,0.647896 kka2_1:2_A65R,kka2_1:2_65,Kka2,kka2_1:2,P00552,,YES,65,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.744,-3.924,2.18,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.295029,0.00709258,0.686498 kka2_1:2_A71F,kka2_1:2_71,Kka2,kka2_1:2,P00552,,YES,71,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.824,-4.432,2.608,,0.553,H,A,0.46,0.08,9.788,,64.39,HHP,-1.74033,0.295029,0.00727707,0.695377 kka2_1:2_A71K,kka2_1:2_71,Kka2,kka2_1:2,P00552,,YES,71,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.824,-2.499,0.675,,0.553,H,A,0.46,0.08,9.788,,64.39,HHP,-1.74033,0.295029,0.00727707,0.765279 kka2_1:2_A71P,kka2_1:2_71,Kka2,kka2_1:2,P00552,,YES,71,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.824,-4.026,2.202,,0.553,H,A,0.46,0.08,9.788,,64.39,HHP,-1.74033,0.295029,0.00727707,0.600382 kka2_1:2_A79P,kka2_1:2_79,Kka2,kka2_1:2,P00552,,YES,79,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.368,-3.3,0.932,,0.563,.,B,0.46,-0.43,0.475,,71.59,HHH,-1.752,0.295029,0.00664821,0.753172 kka2_1:2_A87I,kka2_1:2_87,Kka2,kka2_1:2,P00552,,YES,87,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.917,-4.113,2.196,,1.039,S,L,0.46,1.57,22.675,22.675,65.53,AHO,-1.822,0.295029,0.00791281,0.740017 kka2_1:2_A87K,kka2_1:2_87,Kka2,kka2_1:2,P00552,,YES,87,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.917,-3.626,1.709,,1.039,S,L,0.46,1.57,22.675,22.675,65.53,AHO,-1.822,0.295029,0.00791281,0.806136 kka2_1:2_A87M,kka2_1:2_87,Kka2,kka2_1:2,P00552,,YES,87,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.917,-4.877,2.96,,1.039,S,L,0.46,1.57,22.675,22.675,65.53,AHO,-1.822,0.295029,0.00791281,0.808809 kka2_1:2_A87N,kka2_1:2_87,Kka2,kka2_1:2,P00552,,YES,87,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.917,-2.703,0.786,,1.039,S,L,0.46,1.57,22.675,22.675,65.53,AHO,-1.822,0.295029,0.00791281,0.83531 kka2_1:2_A87R,kka2_1:2_87,Kka2,kka2_1:2,P00552,,YES,87,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.917,-3.21,1.293,,1.039,S,L,0.46,1.57,22.675,22.675,65.53,AHO,-1.822,0.295029,0.00791281,0.83222 kka2_1:2_A87W,kka2_1:2_87,Kka2,kka2_1:2,P00552,,YES,87,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.917,-5.563,3.646,,1.039,S,L,0.46,1.57,22.675,22.675,65.53,AHO,-1.822,0.295029,0.00791281,0.754746 kka2_1:2_A87Y,kka2_1:2_87,Kka2,kka2_1:2,P00552,,YES,87,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.917,-4.401,2.484,,1.039,S,L,0.46,1.57,22.675,22.675,65.53,AHO,-1.822,0.295029,0.00791281,0.798627 kka2_1:2_A9H,kka2_1:2_9,Kka2,kka2_1:2,P00552,,YES,9,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.079,-4.629,2.55,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.295029,0.00273264,0.915051 kka2_1:2_A9K,kka2_1:2_9,Kka2,kka2_1:2,P00552,,YES,9,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.079,-3.506,1.427,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.295029,0.00273264,0.921906 kka2_1:2_C131A,kka2_1:2_131,Kka2,kka2_1:2,P00552,,YES,131,C,A,CA,Special,Hydrophobic,5.07,6,0.93,195,121,89,-32,108.5,88.6,-19.9,-0.831,-2.881,2.05,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.295029,0.00170814,0.484594 kka2_1:2_C131D,kka2_1:2_131,Kka2,kka2_1:2,P00552,,YES,131,C,D,CD,Special,negativeCharge,5.07,5.0516,-0.0184,154,121,133,12,108.5,111.1,2.6,-0.831,-3.947,3.116,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.295029,0.00170814,0.449708 kka2_1:2_C131E,kka2_1:2_131,Kka2,kka2_1:2,P00552,,YES,131,C,E,CE,Special,negativeCharge,5.07,3.22,-1.85,170,121,147,26,108.5,138.4,29.9,-0.831,-4.143,3.312,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.295029,0.00170814,0.440501 kka2_1:2_C131H,kka2_1:2_131,Kka2,kka2_1:2,P00552,,YES,131,C,H,CH,Special,PositiveCharge,5.07,7.59,2.52,174,121,155,34,108.5,153.2,44.7,-0.831,-4.933,4.102,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.295029,0.00170814,0.428069 kka2_1:2_C131I,kka2_1:2_131,Kka2,kka2_1:2,P00552,,YES,131,C,I,CI,Special,Hydrophobic,5.07,6.02,0.95,198,121,131,10,108.5,166.7,58.2,-0.831,-3.589,2.758,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.295029,0.00170814,0.451677 kka2_1:2_C131K,kka2_1:2_131,Kka2,kka2_1:2,P00552,,YES,131,C,K,CK,Special,PositiveCharge,5.07,9.74,4.67,202,121,146,25,108.5,168.6,60.1,-0.831,-3.935,3.104,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.295029,0.00170814,0.458796 kka2_1:2_C131M,kka2_1:2_131,Kka2,kka2_1:2,P00552,,YES,131,C,M,CM,Special,Hydrophobic,5.07,5.74,0.67,196,121,149,28,108.5,162.9,54.4,-0.831,-4.508,3.677,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.295029,0.00170814,0.446769 kka2_1:2_C131P,kka2_1:2_131,Kka2,kka2_1:2,P00552,,YES,131,C,P,CP,Special,Special,5.07,6.3,1.23,169,121,115,-6,108.5,112.7,4.2,-0.831,-4.133,3.302,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.295029,0.00170814,0.460115 kka2_1:2_C131Q,kka2_1:2_131,Kka2,kka2_1:2,P00552,,YES,131,C,Q,CQ,Special,Polar,5.07,6.24429,1.17429,154,121,146,25,108.5,143.8,35.3,-0.831,-4.378,3.547,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.295029,0.00170814,0.43785 kka2_1:2_C31A,kka2_1:2_31,Kka2,kka2_1:2,P00552,,YES,31,C,A,CA,Special,Hydrophobic,5.07,6,0.93,195,121,89,-32,108.5,88.6,-19.9,-2.246,-2.378,0.132,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.295029,0.00681582,0.829941 kka2_1:2_C31D,kka2_1:2_31,Kka2,kka2_1:2,P00552,,YES,31,C,D,CD,Special,negativeCharge,5.07,5.0516,-0.0184,154,121,133,12,108.5,111.1,2.6,-2.246,-3.622,1.376,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.295029,0.00681582,0.676851 kka2_1:2_C31H,kka2_1:2_31,Kka2,kka2_1:2,P00552,,YES,31,C,H,CH,Special,PositiveCharge,5.07,7.59,2.52,174,121,155,34,108.5,153.2,44.7,-2.246,-3.333,1.087,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.295029,0.00681582,0.767785 kka2_1:2_C31M,kka2_1:2_31,Kka2,kka2_1:2,P00552,,YES,31,C,M,CM,Special,Hydrophobic,5.07,5.74,0.67,196,121,149,28,108.5,162.9,54.4,-2.246,-4.677,2.431,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.295029,0.00681582,0.666908 kka2_1:2_C31P,kka2_1:2_31,Kka2,kka2_1:2,P00552,,YES,31,C,P,CP,Special,Special,5.07,6.3,1.23,169,121,115,-6,108.5,112.7,4.2,-2.246,-4.029,1.783,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.295029,0.00681582,0.577649 kka2_1:2_C31Q,kka2_1:2_31,Kka2,kka2_1:2,P00552,,YES,31,C,Q,CQ,Special,Polar,5.07,6.24429,1.17429,154,121,146,25,108.5,143.8,35.3,-2.246,-2.477,0.231,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.295029,0.00681582,0.807346 kka2_1:2_D101L,kka2_1:2_101,Kka2,kka2_1:2,P00552,,YES,101,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.028,-3.645,2.617,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.295029,0.00423361,0.459867 kka2_1:2_D101M,kka2_1:2_101,Kka2,kka2_1:2,P00552,,YES,101,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.028,-4.841,3.813,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.295029,0.00423361,0.457916 kka2_1:2_D101P,kka2_1:2_101,Kka2,kka2_1:2,P00552,,YES,101,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.028,-3.843,2.815,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.295029,0.00423361,0.470171 kka2_1:2_D101V,kka2_1:2_101,Kka2,kka2_1:2,P00552,,YES,101,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.028,-2.595,1.567,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.295029,0.00423361,0.597798 kka2_1:2_D101W,kka2_1:2_101,Kka2,kka2_1:2,P00552,,YES,101,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.028,-5.632,4.604,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.295029,0.00423361,0.426707 kka2_1:2_D118A,kka2_1:2_118,Kka2,kka2_1:2,P00552,,YES,118,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.07,-2.21,0.14,,0.61,H,A,0.75,-0.05,2.237,,64.39,HAH,-1.32367,0.295029,0.0067852,0.76859 kka2_1:2_D118C,kka2_1:2_118,Kka2,kka2_1:2,P00552,,YES,118,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.07,-5.162,3.092,,0.61,H,A,0.75,-0.05,2.237,,64.39,HAH,-1.32367,0.295029,0.0067852,0.702924 kka2_1:2_D118G,kka2_1:2_118,Kka2,kka2_1:2,P00552,,YES,118,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.07,-2.786,0.716,,0.61,H,A,0.75,-0.05,2.237,,64.39,HAH,-1.32367,0.295029,0.0067852,0.679237 kka2_1:2_D118M,kka2_1:2_118,Kka2,kka2_1:2,P00552,,YES,118,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.07,-3.354,1.284,,0.61,H,A,0.75,-0.05,2.237,,64.39,HAH,-1.32367,0.295029,0.0067852,0.64826 kka2_1:2_D118S,kka2_1:2_118,Kka2,kka2_1:2,P00552,,YES,118,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.07,-2.544,0.474,,0.61,H,A,0.75,-0.05,2.237,,64.39,HAH,-1.32367,0.295029,0.0067852,0.721284 kka2_1:2_D118W,kka2_1:2_118,Kka2,kka2_1:2,P00552,,YES,118,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.07,-5.579,3.509,,0.61,H,A,0.75,-0.05,2.237,,64.39,HAH,-1.32367,0.295029,0.0067852,0.613992 kka2_1:2_D127C,kka2_1:2_127,Kka2,kka2_1:2,P00552,,YES,127,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.364,-5.181,3.817,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.295029,0.00660501,0.609851 kka2_1:2_D127K,kka2_1:2_127,Kka2,kka2_1:2,P00552,,YES,127,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.364,-3.534,2.17,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.295029,0.00660501,0.599103 kka2_1:2_D127L,kka2_1:2_127,Kka2,kka2_1:2,P00552,,YES,127,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.364,-3.769,2.405,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.295029,0.00660501,0.550601 kka2_1:2_D127M,kka2_1:2_127,Kka2,kka2_1:2,P00552,,YES,127,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.364,-4.921,3.557,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.295029,0.00660501,0.537531 kka2_1:2_D127P,kka2_1:2_127,Kka2,kka2_1:2,P00552,,YES,127,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.364,-1.54,0.176,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.295029,0.00660501,0.735795 kka2_1:2_D127S,kka2_1:2_127,Kka2,kka2_1:2,P00552,,YES,127,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.364,-3.391,2.027,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.295029,0.00660501,0.607125 kka2_1:2_D127T,kka2_1:2_127,Kka2,kka2_1:2,P00552,,YES,127,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.364,-3.566,2.202,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.295029,0.00660501,0.616864 kka2_1:2_D127W,kka2_1:2_127,Kka2,kka2_1:2,P00552,,YES,127,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.364,-5.662,4.298,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.295029,0.00660501,0.50991 kka2_1:2_D134W,kka2_1:2_134,Kka2,kka2_1:2,P00552,,YES,134,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.969,-5.579,4.61,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.295029,0.00270812,0.670629 kka2_1:2_D154L,kka2_1:2_154,Kka2,kka2_1:2,P00552,,YES,154,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.876,-3.838,2.962,,0.457,,b,0.29,1.48,3.631,,52.65,HAP,-1.52467,0.295029,0.00292633,0.705079 kka2_1:2_D154P,kka2_1:2_154,Kka2,kka2_1:2,P00552,,YES,154,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.876,-3.765,2.889,,0.457,,b,0.29,1.48,3.631,,52.65,HAP,-1.52467,0.295029,0.00292633,0.702423 kka2_1:2_D154W,kka2_1:2_154,Kka2,kka2_1:2,P00552,,YES,154,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.876,-5.609,4.733,,0.457,,b,0.29,1.48,3.631,,52.65,HAP,-1.52467,0.295029,0.00292633,0.700528 kka2_1:2_D156L,kka2_1:2_156,Kka2,kka2_1:2,P00552,,YES,156,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.696,-3.635,1.939,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.295029,0.00926998,0.79549 kka2_1:2_D157L,kka2_1:2_157,Kka2,kka2_1:2,P00552,,YES,157,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.993,-3.843,2.85,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.295029,0.0042313,0.59214 kka2_1:2_D157M,kka2_1:2_157,Kka2,kka2_1:2,P00552,,YES,157,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.993,-4.965,3.972,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.295029,0.0042313,0.635357 kka2_1:2_D157P,kka2_1:2_157,Kka2,kka2_1:2,P00552,,YES,157,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.993,-3.813,2.82,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.295029,0.0042313,0.608318 kka2_1:2_D157W,kka2_1:2_157,Kka2,kka2_1:2,P00552,,YES,157,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.993,-5.591,4.598,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.295029,0.0042313,0.628696 kka2_1:2_D159S,kka2_1:2_159,Kka2,kka2_1:2,P00552,,YES,159,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.82,-3.223,2.403,,0.28,.,B,0.75,1.25,0.899,,48.11,HAA,-1.48333,0.295029,0.0030485,0.53199 kka2_1:2_D180A,kka2_1:2_180,Kka2,kka2_1:2,P00552,,YES,180,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.416,-2.13,-0.286,,1.03,S,a,0.75,1.5,1.27,,71.59,OAO,-2.02933,0.295029,0.00756412,0.918838 kka2_1:2_D180L,kka2_1:2_180,Kka2,kka2_1:2,P00552,,YES,180,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.416,-2.808,0.392,,1.03,S,a,0.75,1.5,1.27,,71.59,OAO,-2.02933,0.295029,0.00756412,0.842533 kka2_1:2_D180M,kka2_1:2_180,Kka2,kka2_1:2,P00552,,YES,180,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.416,-3.738,1.322,,1.03,S,a,0.75,1.5,1.27,,71.59,OAO,-2.02933,0.295029,0.00756412,0.871265 kka2_1:2_D180P,kka2_1:2_180,Kka2,kka2_1:2,P00552,,YES,180,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.416,-3.147,0.731,,1.03,S,a,0.75,1.5,1.27,,71.59,OAO,-2.02933,0.295029,0.00756412,0.79965 kka2_1:2_D190W,kka2_1:2_190,Kka2,kka2_1:2,P00552,,YES,190,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.708,-5.576,4.868,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.295029,0.00247989,0.37043 kka2_1:2_D216A,kka2_1:2_216,Kka2,kka2_1:2,P00552,,YES,216,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.785,-3.354,2.569,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.295029,0.00229969,0.490309 kka2_1:2_D216C,kka2_1:2_216,Kka2,kka2_1:2,P00552,,YES,216,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.785,-5.139,4.354,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.295029,0.00229969,0.505588 kka2_1:2_D216G,kka2_1:2_216,Kka2,kka2_1:2,P00552,,YES,216,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.785,-3.205,2.42,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.295029,0.00229969,0.515617 kka2_1:2_D216P,kka2_1:2_216,Kka2,kka2_1:2,P00552,,YES,216,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.785,-3.727,2.942,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.295029,0.00229969,0.481343 kka2_1:2_D216S,kka2_1:2_216,Kka2,kka2_1:2,P00552,,YES,216,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.785,-3.233,2.448,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.295029,0.00229969,0.51275 kka2_1:2_D227R,kka2_1:2_227,Kka2,kka2_1:2,P00552,,YES,227,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.758,-3.84,2.082,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.295029,0.00745029,0.487399 kka2_1:2_D238F,kka2_1:2_238,Kka2,kka2_1:2,P00552,,YES,238,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.83,-4.489,1.659,,0.604,H,A,0.75,-0.33,22.789,22.789,92.05,HAB,-2.633,0.295029,0.0113863,0.904635 kka2_1:2_D238I,kka2_1:2_238,Kka2,kka2_1:2,P00552,,YES,238,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.83,-4.106,1.276,,0.604,H,A,0.75,-0.33,22.789,22.789,92.05,HAB,-2.633,0.295029,0.0113863,0.888619 kka2_1:2_D238M,kka2_1:2_238,Kka2,kka2_1:2,P00552,,YES,238,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.83,-3.594,0.764,,0.604,H,A,0.75,-0.33,22.789,22.789,92.05,HAB,-2.633,0.295029,0.0113863,0.91541 kka2_1:2_D238P,kka2_1:2_238,Kka2,kka2_1:2,P00552,,YES,238,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.83,-2.766,-0.064,,0.604,H,A,0.75,-0.33,22.789,22.789,92.05,HAB,-2.633,0.295029,0.0113863,0.885658 kka2_1:2_D238R,kka2_1:2_238,Kka2,kka2_1:2,P00552,,YES,238,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.83,-2.777,-0.053,,0.604,H,A,0.75,-0.33,22.789,22.789,92.05,HAB,-2.633,0.295029,0.0113863,0.953704 kka2_1:2_D23P,kka2_1:2_23,Kka2,kka2_1:2,P00552,,YES,23,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.459,-3.293,0.834,,0.695,E,B,0.75,-0.65,18.207,18.207,65.53,HAH,-1.94033,0.295029,0.007195,0.851744 kka2_1:2_D23W,kka2_1:2_23,Kka2,kka2_1:2,P00552,,YES,23,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.459,-5.599,3.14,,0.695,E,B,0.75,-0.65,18.207,18.207,65.53,HAH,-1.94033,0.295029,0.007195,0.8014 kka2_1:2_D33M,kka2_1:2_33,Kka2,kka2_1:2,P00552,,YES,33,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.186,-4.904,2.718,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.295029,0.00633568,0.756873 kka2_1:2_D33P,kka2_1:2_33,Kka2,kka2_1:2,P00552,,YES,33,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.186,-2.939,0.753,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.295029,0.00633568,0.714122 kka2_1:2_D33V,kka2_1:2_33,Kka2,kka2_1:2,P00552,,YES,33,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.186,-3.782,1.596,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.295029,0.00633568,0.758694 kka2_1:2_D33W,kka2_1:2_33,Kka2,kka2_1:2,P00552,,YES,33,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.186,-5.589,3.403,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.295029,0.00633568,0.722777 kka2_1:2_D52M,kka2_1:2_52,Kka2,kka2_1:2,P00552,,YES,52,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.271,-4.777,2.506,,0.22,E,B,0.75,0.8,1.123,,71.59,PAH,-2.38367,0.295029,0.00175694,0.751588 kka2_1:2_D52P,kka2_1:2_52,Kka2,kka2_1:2,P00552,,YES,52,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.271,-3.706,1.435,,0.22,E,B,0.75,0.8,1.123,,71.59,PAH,-2.38367,0.295029,0.00175694,0.645143 kka2_1:2_D52Q,kka2_1:2_52,Kka2,kka2_1:2,P00552,,YES,52,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.271,-3.313,1.042,,0.22,E,B,0.75,0.8,1.123,,71.59,PAH,-2.38367,0.295029,0.00175694,0.806237 kka2_1:2_D5C,kka2_1:2_5,Kka2,kka2_1:2,P00552,,YES,5,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.306,-4.968,3.662,,,,,,,,,71.59,PAO,-1.784,0.295029,0.00222864,1.02802 kka2_1:2_D5I,kka2_1:2_5,Kka2,kka2_1:2,P00552,,YES,5,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.306,-3.821,2.515,,,,,,,,,71.59,PAO,-1.784,0.295029,0.00222864,1.0217 kka2_1:2_D5P,kka2_1:2_5,Kka2,kka2_1:2,P00552,,YES,5,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.306,-3.466,2.16,,,,,,,,,71.59,PAO,-1.784,0.295029,0.00222864,1.06923 kka2_1:2_D5W,kka2_1:2_5,Kka2,kka2_1:2,P00552,,YES,5,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.306,-5.278,3.972,,,,,,,,,71.59,PAO,-1.784,0.295029,0.00222864,1.01759 kka2_1:2_D62C,kka2_1:2_62,Kka2,kka2_1:2,P00552,,YES,62,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.591,-5.15,3.559,,0.262,H,A,0.75,0.08,10.048,10.048,64.39,PAA,-1.77833,0.295029,0.00744243,0.531162 kka2_1:2_D62P,kka2_1:2_62,Kka2,kka2_1:2,P00552,,YES,62,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.591,-3.966,2.375,,0.262,H,A,0.75,0.08,10.048,10.048,64.39,PAA,-1.77833,0.295029,0.00744243,0.499135 kka2_1:2_D62R,kka2_1:2_62,Kka2,kka2_1:2,P00552,,YES,62,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.591,-3.972,2.381,,0.262,H,A,0.75,0.08,10.048,10.048,64.39,PAA,-1.77833,0.295029,0.00744243,0.513939 kka2_1:2_D62S,kka2_1:2_62,Kka2,kka2_1:2,P00552,,YES,62,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.591,-3.356,1.765,,0.262,H,A,0.75,0.08,10.048,10.048,64.39,PAA,-1.77833,0.295029,0.00744243,0.529483 kka2_1:2_D62T,kka2_1:2_62,Kka2,kka2_1:2,P00552,,YES,62,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.591,-3.648,2.057,,0.262,H,A,0.75,0.08,10.048,10.048,64.39,PAA,-1.77833,0.295029,0.00744243,0.522 kka2_1:2_D62V,kka2_1:2_62,Kka2,kka2_1:2,P00552,,YES,62,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.591,-3.746,2.155,,0.262,H,A,0.75,0.08,10.048,10.048,64.39,PAA,-1.77833,0.295029,0.00744243,0.517619 kka2_1:2_D62W,kka2_1:2_62,Kka2,kka2_1:2,P00552,,YES,62,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.591,-5.508,3.917,,0.262,H,A,0.75,0.08,10.048,10.048,64.39,PAA,-1.77833,0.295029,0.00744243,0.455422 kka2_1:2_D82C,kka2_1:2_82,Kka2,kka2_1:2,P00552,,YES,82,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.946,-3.559,1.613,,0.341,E,b,0.75,0.52,11.923,11.923,63.64,HAH,-1.98,0.295029,0.00637516,0.534737 kka2_1:2_D82F,kka2_1:2_82,Kka2,kka2_1:2,P00552,,YES,82,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.946,-4.41,2.464,,0.341,E,b,0.75,0.52,11.923,11.923,63.64,HAH,-1.98,0.295029,0.00637516,0.520986 kka2_1:2_D82M,kka2_1:2_82,Kka2,kka2_1:2,P00552,,YES,82,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.946,-4.849,2.903,,0.341,E,b,0.75,0.52,11.923,11.923,63.64,HAH,-1.98,0.295029,0.00637516,0.564205 kka2_1:2_D82P,kka2_1:2_82,Kka2,kka2_1:2,P00552,,YES,82,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.946,-4.009,2.063,,0.341,E,b,0.75,0.52,11.923,11.923,63.64,HAH,-1.98,0.295029,0.00637516,0.45714 kka2_1:2_D82S,kka2_1:2_82,Kka2,kka2_1:2,P00552,,YES,82,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.946,-2.906,0.96,,0.341,E,b,0.75,0.52,11.923,11.923,63.64,HAH,-1.98,0.295029,0.00637516,0.564635 kka2_1:2_D82W,kka2_1:2_82,Kka2,kka2_1:2,P00552,,YES,82,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.946,-3.611,1.665,,0.341,E,b,0.75,0.52,11.923,11.923,63.64,HAH,-1.98,0.295029,0.00637516,0.507527 kka2_1:2_D90C,kka2_1:2_90,Kka2,kka2_1:2,P00552,,YES,90,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.459,-5.259,2.8,,0.104,E,B,0.75,0.73,6.085,,64.39,BAH,-1.72833,0.295029,0.00583842,0.694145 kka2_1:2_D90L,kka2_1:2_90,Kka2,kka2_1:2,P00552,,YES,90,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.459,-3.657,1.198,,0.104,E,B,0.75,0.73,6.085,,64.39,BAH,-1.72833,0.295029,0.00583842,0.498138 kka2_1:2_D90M,kka2_1:2_90,Kka2,kka2_1:2,P00552,,YES,90,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.459,-4.83,2.371,,0.104,E,B,0.75,0.73,6.085,,64.39,BAH,-1.72833,0.295029,0.00583842,0.57929 kka2_1:2_D90R,kka2_1:2_90,Kka2,kka2_1:2,P00552,,YES,90,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.459,-2.746,0.287,,0.104,E,B,0.75,0.73,6.085,,64.39,BAH,-1.72833,0.295029,0.00583842,0.594058 kka2_1:2_D90S,kka2_1:2_90,Kka2,kka2_1:2,P00552,,YES,90,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.459,-2.612,0.153,,0.104,E,B,0.75,0.73,6.085,,64.39,BAH,-1.72833,0.295029,0.00583842,0.618094 kka2_1:2_D90T,kka2_1:2_90,Kka2,kka2_1:2,P00552,,YES,90,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.459,-3.035,0.576,,0.104,E,B,0.75,0.73,6.085,,64.39,BAH,-1.72833,0.295029,0.00583842,0.56113 kka2_1:2_D90W,kka2_1:2_90,Kka2,kka2_1:2,P00552,,YES,90,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.459,-3.595,1.136,,0.104,E,B,0.75,0.73,6.085,,64.39,BAH,-1.72833,0.295029,0.00583842,0.485798 kka2_1:2_E111C,kka2_1:2_111,Kka2,kka2_1:2,P00552,,YES,111,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.28,-5.229,2.949,,0.155,H,A,1.52,-1.14,2.792,,65.53,HAB,-2.27833,0.295029,0.00746789,0.667263 kka2_1:2_E142I,kka2_1:2_142,Kka2,kka2_1:2,P00552,,YES,142,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.221,-4.073,1.852,,0.471,H,A,1.52,0.85,3.693,,65.53,HAB,-2.08033,0.295029,0.00748883,0.676267 kka2_1:2_E142S,kka2_1:2_142,Kka2,kka2_1:2,P00552,,YES,142,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.221,-2.618,0.397,,0.471,H,A,1.52,0.85,3.693,,65.53,HAB,-2.08033,0.295029,0.00748883,0.766496 kka2_1:2_E149C,kka2_1:2_149,Kka2,kka2_1:2,P00552,,YES,149,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.994,-5.217,3.223,,0.674,H,A,1.04,1.63,15.361,15.361,71.59,HAH,-1.59667,0.295029,0.00803343,0.893903 kka2_1:2_E149F,kka2_1:2_149,Kka2,kka2_1:2,P00552,,YES,149,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.994,-4.387,2.393,,0.674,H,A,1.04,1.63,15.361,15.361,71.59,HAH,-1.59667,0.295029,0.00803343,0.939639 kka2_1:2_E149L,kka2_1:2_149,Kka2,kka2_1:2,P00552,,YES,149,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.994,-2.522,0.528,,0.674,H,A,1.04,1.63,15.361,15.361,71.59,HAH,-1.59667,0.295029,0.00803343,0.876589 kka2_1:2_E149M,kka2_1:2_149,Kka2,kka2_1:2,P00552,,YES,149,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.994,-3.564,1.57,,0.674,H,A,1.04,1.63,15.361,15.361,71.59,HAH,-1.59667,0.295029,0.00803343,0.88597 kka2_1:2_E149P,kka2_1:2_149,Kka2,kka2_1:2,P00552,,YES,149,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.994,-4.051,2.057,,0.674,H,A,1.04,1.63,15.361,15.361,71.59,HAH,-1.59667,0.295029,0.00803343,0.816241 kka2_1:2_E149S,kka2_1:2_149,Kka2,kka2_1:2,P00552,,YES,149,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.994,-2.804,0.81,,0.674,H,A,1.04,1.63,15.361,15.361,71.59,HAH,-1.59667,0.295029,0.00803343,0.877622 kka2_1:2_E160L,kka2_1:2_160,Kka2,kka2_1:2,P00552,,YES,160,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.683,-3.761,2.078,,0.989,G,A,1.04,2.28,3.948,,71.59,AAA,-1.36133,0.295029,0.00935762,0.938925 kka2_1:2_E160M,kka2_1:2_160,Kka2,kka2_1:2,P00552,,YES,160,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.683,-4.919,3.236,,0.989,G,A,1.04,2.28,3.948,,71.59,AAA,-1.36133,0.295029,0.00935762,0.917157 kka2_1:2_E160P,kka2_1:2_160,Kka2,kka2_1:2,P00552,,YES,160,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.683,-2.472,0.789,,0.989,G,A,1.04,2.28,3.948,,71.59,AAA,-1.36133,0.295029,0.00935762,0.814015 kka2_1:2_E160S,kka2_1:2_160,Kka2,kka2_1:2,P00552,,YES,160,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.683,-3.324,1.641,,0.989,G,A,1.04,2.28,3.948,,71.59,AAA,-1.36133,0.295029,0.00935762,0.829344 kka2_1:2_E161S,kka2_1:2_161,Kka2,kka2_1:2,P00552,,YES,161,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.581,-2.422,0.841,,0.829,G,A,1.52,2.24,1.612,,92.05,AAB,-1.861,0.295029,0.00760103,0.746748 kka2_1:2_E169G,kka2_1:2_169,Kka2,kka2_1:2,P00552,,YES,169,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.996,-2.941,0.945,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.295029,0.00730086,0.617941 kka2_1:2_E169I,kka2_1:2_169,Kka2,kka2_1:2,P00552,,YES,169,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.996,-4.06,2.064,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.295029,0.00730086,0.660481 kka2_1:2_E169R,kka2_1:2_169,Kka2,kka2_1:2,P00552,,YES,169,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.996,-3.888,1.892,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.295029,0.00730086,0.66694 kka2_1:2_E17I,kka2_1:2_17,Kka2,kka2_1:2,P00552,,YES,17,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.154,-4.159,2.005,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.295029,0.00688738,0.63946 kka2_1:2_E17N,kka2_1:2_17,Kka2,kka2_1:2,P00552,,YES,17,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.154,-3.14,0.986,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.295029,0.00688738,0.766443 kka2_1:2_E17T,kka2_1:2_17,Kka2,kka2_1:2,P00552,,YES,17,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.154,-2.882,0.728,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.295029,0.00688738,0.774507 kka2_1:2_E17V,kka2_1:2_17,Kka2,kka2_1:2,P00552,,YES,17,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.154,-3.778,1.624,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.295029,0.00688738,0.687369 kka2_1:2_E17W,kka2_1:2_17,Kka2,kka2_1:2,P00552,,YES,17,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.154,-5.592,3.438,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.295029,0.00688738,0.640258 kka2_1:2_E17Y,kka2_1:2_17,Kka2,kka2_1:2,P00552,,YES,17,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.154,-4.407,2.253,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.295029,0.00688738,0.666045 kka2_1:2_E182C,kka2_1:2_182,Kka2,kka2_1:2,P00552,,YES,182,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.516,-3.433,1.917,,0.326,,B,1.52,0.75,14.547,14.547,65.53,OAA,-1.806,0.295029,0.00641548,0.500607 kka2_1:2_E182M,kka2_1:2_182,Kka2,kka2_1:2,P00552,,YES,182,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.516,-4.818,3.302,,0.326,,B,1.52,0.75,14.547,14.547,65.53,OAA,-1.806,0.295029,0.00641548,0.478366 kka2_1:2_E182P,kka2_1:2_182,Kka2,kka2_1:2,P00552,,YES,182,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.516,-3.948,2.432,,0.326,,B,1.52,0.75,14.547,14.547,65.53,OAA,-1.806,0.295029,0.00641548,0.472823 kka2_1:2_E182W,kka2_1:2_182,Kka2,kka2_1:2,P00552,,YES,182,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.516,-5.341,3.825,,0.326,,B,1.52,0.75,14.547,14.547,65.53,OAA,-1.806,0.295029,0.00641548,0.458711 kka2_1:2_E235F,kka2_1:2_235,Kka2,kka2_1:2,P00552,,YES,235,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.955,-4.481,2.526,,0.631,H,A,1.04,0.12,26.048,26.048,65.53,OAH,-2.07267,0.295029,0.0102806,0.835869 kka2_1:2_E235M,kka2_1:2_235,Kka2,kka2_1:2,P00552,,YES,235,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.955,-4.796,2.841,,0.631,H,A,1.04,0.12,26.048,26.048,65.53,OAH,-2.07267,0.295029,0.0102806,0.812486 kka2_1:2_E235S,kka2_1:2_235,Kka2,kka2_1:2,P00552,,YES,235,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.955,-2.915,0.96,,0.631,H,A,1.04,0.12,26.048,26.048,65.53,OAH,-2.07267,0.295029,0.0102806,0.659997 kka2_1:2_E262R,kka2_1:2_262,Kka2,kka2_1:2,P00552,,YES,262,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-0.829,-3.509,2.68,,0.059,G,A,1.04,-0.18,2.383,,42.42,AAH,-0.816,0.295029,0.0191586,0.476842 kka2_1:2_E262S,kka2_1:2_262,Kka2,kka2_1:2,P00552,,YES,262,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-0.829,-3.212,2.383,,0.059,G,A,1.04,-0.18,2.383,,42.42,AAH,-0.816,0.295029,0.0191586,0.523868 kka2_1:2_E3M,kka2_1:2_3,Kka2,kka2_1:2,P00552,,YES,3,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.199,-4.633,2.434,,,,,,,7.22,,92.05,HAP,-2.11567,0.295029,0.00267607,1.01845 kka2_1:2_E3S,kka2_1:2_3,Kka2,kka2_1:2,P00552,,YES,3,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.199,-2.253,0.054,,,,,,,7.22,,92.05,HAP,-2.11567,0.295029,0.00267607,1.00394 kka2_1:2_E3T,kka2_1:2_3,Kka2,kka2_1:2,P00552,,YES,3,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.199,-3.32,1.121,,,,,,,7.22,,92.05,HAP,-2.11567,0.295029,0.00267607,1.00216 kka2_1:2_E59A,kka2_1:2_59,Kka2,kka2_1:2,P00552,,YES,59,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-0.952,-3.166,2.214,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.295029,0.00280355,0.504423 kka2_1:2_E59C,kka2_1:2_59,Kka2,kka2_1:2,P00552,,YES,59,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-0.952,-5.289,4.337,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.295029,0.00280355,0.514026 kka2_1:2_E59H,kka2_1:2_59,Kka2,kka2_1:2,P00552,,YES,59,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-0.952,-4.372,3.42,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.295029,0.00280355,0.43466 kka2_1:2_E59M,kka2_1:2_59,Kka2,kka2_1:2,P00552,,YES,59,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-0.952,-4.747,3.795,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.295029,0.00280355,0.450574 kka2_1:2_E59N,kka2_1:2_59,Kka2,kka2_1:2,P00552,,YES,59,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-0.952,-3.52,2.568,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.295029,0.00280355,0.428148 kka2_1:2_E59S,kka2_1:2_59,Kka2,kka2_1:2,P00552,,YES,59,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-0.952,-3.233,2.281,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.295029,0.00280355,0.537668 kka2_1:2_E59T,kka2_1:2_59,Kka2,kka2_1:2,P00552,,YES,59,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-0.952,-2.667,1.715,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.295029,0.00280355,0.563132 kka2_1:2_E59W,kka2_1:2_59,Kka2,kka2_1:2,P00552,,YES,59,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-0.952,-5.39,4.438,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.295029,0.00280355,0.423449 kka2_1:2_E63C,kka2_1:2_63,Kka2,kka2_1:2,P00552,,YES,63,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-0.762,-5.34,4.578,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.295029,0.00118399,0.465343 kka2_1:2_E63F,kka2_1:2_63,Kka2,kka2_1:2,P00552,,YES,63,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-0.762,-4.32,3.558,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.295029,0.00118399,0.397762 kka2_1:2_E63I,kka2_1:2_63,Kka2,kka2_1:2,P00552,,YES,63,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-0.762,-4.039,3.277,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.295029,0.00118399,0.397831 kka2_1:2_E63M,kka2_1:2_63,Kka2,kka2_1:2,P00552,,YES,63,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-0.762,-4.733,3.971,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.295029,0.00118399,0.431662 kka2_1:2_E63P,kka2_1:2_63,Kka2,kka2_1:2,P00552,,YES,63,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-0.762,-3.683,2.921,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.295029,0.00118399,0.435461 kka2_1:2_E63Q,kka2_1:2_63,Kka2,kka2_1:2,P00552,,YES,63,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-0.762,-3.253,2.491,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.295029,0.00118399,0.441862 kka2_1:2_E63R,kka2_1:2_63,Kka2,kka2_1:2,P00552,,YES,63,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-0.762,-3.511,2.749,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.295029,0.00118399,0.446998 kka2_1:2_E63S,kka2_1:2_63,Kka2,kka2_1:2,P00552,,YES,63,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-0.762,-3.189,2.427,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.295029,0.00118399,0.487435 kka2_1:2_E63T,kka2_1:2_63,Kka2,kka2_1:2,P00552,,YES,63,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-0.762,-3.45,2.688,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.295029,0.00118399,0.455346 kka2_1:2_E63W,kka2_1:2_63,Kka2,kka2_1:2,P00552,,YES,63,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-0.762,-5.351,4.589,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.295029,0.00118399,0.398373 kka2_1:2_E86A,kka2_1:2_86,Kka2,kka2_1:2,P00552,,YES,86,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.86,-2.331,0.471,,0.369,.,B,1.04,1.92,3.573,,63.26,PAH,-1.98067,0.295029,0.00642858,0.663696 kka2_1:2_E86C,kka2_1:2_86,Kka2,kka2_1:2,P00552,,YES,86,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.86,-5.228,3.368,,0.369,.,B,1.04,1.92,3.573,,63.26,PAH,-1.98067,0.295029,0.00642858,0.643416 kka2_1:2_E86I,kka2_1:2_86,Kka2,kka2_1:2,P00552,,YES,86,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.86,-4.165,2.305,,0.369,.,B,1.04,1.92,3.573,,63.26,PAH,-1.98067,0.295029,0.00642858,0.564296 kka2_1:2_E86L,kka2_1:2_86,Kka2,kka2_1:2,P00552,,YES,86,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.86,-3.758,1.898,,0.369,.,B,1.04,1.92,3.573,,63.26,PAH,-1.98067,0.295029,0.00642858,0.601976 kka2_1:2_E86M,kka2_1:2_86,Kka2,kka2_1:2,P00552,,YES,86,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.86,-4.913,3.053,,0.369,.,B,1.04,1.92,3.573,,63.26,PAH,-1.98067,0.295029,0.00642858,0.618322 kka2_1:2_E86N,kka2_1:2_86,Kka2,kka2_1:2,P00552,,YES,86,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.86,-3.654,1.794,,0.369,.,B,1.04,1.92,3.573,,63.26,PAH,-1.98067,0.295029,0.00642858,0.624186 kka2_1:2_E86P,kka2_1:2_86,Kka2,kka2_1:2,P00552,,YES,86,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.86,-3.983,2.123,,0.369,.,B,1.04,1.92,3.573,,63.26,PAH,-1.98067,0.295029,0.00642858,0.543112 kka2_1:2_E86S,kka2_1:2_86,Kka2,kka2_1:2,P00552,,YES,86,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.86,-2.884,1.024,,0.369,.,B,1.04,1.92,3.573,,63.26,PAH,-1.98067,0.295029,0.00642858,0.654681 kka2_1:2_E86T,kka2_1:2_86,Kka2,kka2_1:2,P00552,,YES,86,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.86,-3.681,1.821,,0.369,.,B,1.04,1.92,3.573,,63.26,PAH,-1.98067,0.295029,0.00642858,0.598208 kka2_1:2_E86V,kka2_1:2_86,Kka2,kka2_1:2,P00552,,YES,86,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.86,-3.786,1.926,,0.369,.,B,1.04,1.92,3.573,,63.26,PAH,-1.98067,0.295029,0.00642858,0.607932 kka2_1:2_E86W,kka2_1:2_86,Kka2,kka2_1:2,P00552,,YES,86,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.86,-5.389,3.529,,0.369,.,B,1.04,1.92,3.573,,63.26,PAH,-1.98067,0.295029,0.00642858,0.601414 kka2_1:2_E96C,kka2_1:2_96,Kka2,kka2_1:2,P00552,,YES,96,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.573,-4.752,2.179,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.295029,0.00369441,0.69018 kka2_1:2_E96S,kka2_1:2_96,Kka2,kka2_1:2,P00552,,YES,96,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.573,-3.194,0.621,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.295029,0.00369441,0.675695 kka2_1:2_F133A,kka2_1:2_133,Kka2,kka2_1:2,P00552,,YES,133,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-0.871,-3.354,2.483,,0.178,.,B,0.58,0.43,1.999,,42.42,OHA,-0.871667,0.295029,0.00182168,0.471435 kka2_1:2_F133E,kka2_1:2_133,Kka2,kka2_1:2,P00552,,YES,133,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-0.871,-3.916,3.045,,0.178,.,B,0.58,0.43,1.999,,42.42,OHA,-0.871667,0.295029,0.00182168,0.426304 kka2_1:2_F133G,kka2_1:2_133,Kka2,kka2_1:2,P00552,,YES,133,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-0.871,-3.635,2.764,,0.178,.,B,0.58,0.43,1.999,,42.42,OHA,-0.871667,0.295029,0.00182168,0.4781 kka2_1:2_F133N,kka2_1:2_133,Kka2,kka2_1:2,P00552,,YES,133,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-0.871,-4.149,3.278,,0.178,.,B,0.58,0.43,1.999,,42.42,OHA,-0.871667,0.295029,0.00182168,0.430492 kka2_1:2_F133P,kka2_1:2_133,Kka2,kka2_1:2,P00552,,YES,133,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-0.871,-4.356,3.485,,0.178,.,B,0.58,0.43,1.999,,42.42,OHA,-0.871667,0.295029,0.00182168,0.45915 kka2_1:2_F133T,kka2_1:2_133,Kka2,kka2_1:2,P00552,,YES,133,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-0.871,-3.698,2.827,,0.178,.,B,0.58,0.43,1.999,,42.42,OHA,-0.871667,0.295029,0.00182168,0.462771 kka2_1:2_F171A,kka2_1:2_171,Kka2,kka2_1:2,P00552,,YES,171,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.326,-3.394,2.068,,0.154,H,A,0.58,-0.1,2.645,,63.64,HHH,-1.45433,0.295029,0.00821426,0.452781 kka2_1:2_F171D,kka2_1:2_171,Kka2,kka2_1:2,P00552,,YES,171,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.326,-4.095,2.769,,0.154,H,A,0.58,-0.1,2.645,,63.64,HHH,-1.45433,0.295029,0.00821426,0.408909 kka2_1:2_F171H,kka2_1:2_171,Kka2,kka2_1:2,P00552,,YES,171,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.326,-3.195,1.869,,0.154,H,A,0.58,-0.1,2.645,,63.64,HHH,-1.45433,0.295029,0.00821426,0.438831 kka2_1:2_F171P,kka2_1:2_171,Kka2,kka2_1:2,P00552,,YES,171,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.326,-4.354,3.028,,0.154,H,A,0.58,-0.1,2.645,,63.64,HHH,-1.45433,0.295029,0.00821426,0.439657 kka2_1:2_F171Q,kka2_1:2_171,Kka2,kka2_1:2,P00552,,YES,171,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.326,-4.325,2.999,,0.154,H,A,0.58,-0.1,2.645,,63.64,HHH,-1.45433,0.295029,0.00821426,0.432305 kka2_1:2_F171R,kka2_1:2_171,Kka2,kka2_1:2,P00552,,YES,171,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.326,-4.175,2.849,,0.154,H,A,0.58,-0.1,2.645,,63.64,HHH,-1.45433,0.295029,0.00821426,0.487745 kka2_1:2_F206R,kka2_1:2_206,Kka2,kka2_1:2,P00552,,YES,206,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.349,-4.172,2.823,,0.006,E,B,0.58,-1.21,0.978,,63.64,OHH,-1.04,0.295029,0.00936868,0.477127 kka2_1:2_F20A,kka2_1:2_20,Kka2,kka2_1:2,P00552,,YES,20,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-3.354,-1.671,-1.683,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.295029,0.00701744,1.07649 kka2_1:2_F20G,kka2_1:2_20,Kka2,kka2_1:2,P00552,,YES,20,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-3.354,-2.338,-1.016,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.295029,0.00701744,1.0564 kka2_1:2_F20I,kka2_1:2_20,Kka2,kka2_1:2,P00552,,YES,20,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-3.354,-3.918,0.564,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.295029,0.00701744,0.895193 kka2_1:2_F20K,kka2_1:2_20,Kka2,kka2_1:2,P00552,,YES,20,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-3.354,-2.992,-0.362,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.295029,0.00701744,1.01282 kka2_1:2_F20N,kka2_1:2_20,Kka2,kka2_1:2,P00552,,YES,20,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-3.354,-3.854,0.5,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.295029,0.00701744,0.936444 kka2_1:2_F20P,kka2_1:2_20,Kka2,kka2_1:2,P00552,,YES,20,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-3.354,-2.906,-0.448,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.295029,0.00701744,0.989338 kka2_1:2_F20R,kka2_1:2_20,Kka2,kka2_1:2,P00552,,YES,20,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-3.354,-2.757,-0.597,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.295029,0.00701744,1.06839 kka2_1:2_F20T,kka2_1:2_20,Kka2,kka2_1:2,P00552,,YES,20,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-3.354,-2.596,-0.758,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.295029,0.00701744,1.07603 kka2_1:2_F20W,kka2_1:2_20,Kka2,kka2_1:2,P00552,,YES,20,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-3.354,-5.49,2.136,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.295029,0.00701744,0.948255 kka2_1:2_F240A,kka2_1:2_240,Kka2,kka2_1:2,P00552,,YES,240,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-0.911,-3.329,2.418,,,H,A,0.58,-1.21,0.373,,50.38,BHH,-1.67267,0.295029,0.00552543,0.456214 kka2_1:2_F240D,kka2_1:2_240,Kka2,kka2_1:2,P00552,,YES,240,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-0.911,-4.011,3.1,,,H,A,0.58,-1.21,0.373,,50.38,BHH,-1.67267,0.295029,0.00552543,0.399312 kka2_1:2_F240K,kka2_1:2_240,Kka2,kka2_1:2,P00552,,YES,240,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-0.911,-3.934,3.023,,,H,A,0.58,-1.21,0.373,,50.38,BHH,-1.67267,0.295029,0.00552543,0.398215 kka2_1:2_F256R,kka2_1:2_256,Kka2,kka2_1:2,P00552,,YES,256,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.49,-3.099,1.609,,,H,A,0.58,-0.78,1.653,,53.03,HHH,-1.423,0.295029,0.0132841,0.496035 kka2_1:2_F263A,kka2_1:2_263,Kka2,kka2_1:2,P00552,,YES,263,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-0.911,-3.329,2.418,,0.006,G,A,1.62,-0.12,5.275,,45.83,AHH,-0.92,0.295029,0.0172454,0.398652 kka2_1:2_F263D,kka2_1:2_263,Kka2,kka2_1:2,P00552,,YES,263,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-0.911,-4.011,3.1,,0.006,G,A,1.62,-0.12,5.275,,45.83,AHH,-0.92,0.295029,0.0172454,0.365132 kka2_1:2_F264R,kka2_1:2_264,Kka2,kka2_1:2,P00552,,YES,264,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.02,-4.192,3.172,,0.296,.,?,0.58,0.02,2.303,,71.59,HHNA,-0.9655,0.295029,,0.493054 kka2_1:2_F37C,kka2_1:2_37,Kka2,kka2_1:2,P00552,,YES,37,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.427,-4.988,3.561,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.295029,0.00586193,0.538971 kka2_1:2_F37E,kka2_1:2_37,Kka2,kka2_1:2,P00552,,YES,37,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.427,-3.871,2.444,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.295029,0.00586193,0.403793 kka2_1:2_F37K,kka2_1:2_37,Kka2,kka2_1:2,P00552,,YES,37,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.427,-3.907,2.48,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.295029,0.00586193,0.413283 kka2_1:2_F37N,kka2_1:2_37,Kka2,kka2_1:2,P00552,,YES,37,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.427,-4.089,2.662,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.295029,0.00586193,0.397089 kka2_1:2_F37P,kka2_1:2_37,Kka2,kka2_1:2,P00552,,YES,37,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.427,-4.289,2.862,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.295029,0.00586193,0.439441 kka2_1:2_F37T,kka2_1:2_37,Kka2,kka2_1:2,P00552,,YES,37,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.427,-3.702,2.275,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.295029,0.00586193,0.474474 kka2_1:2_F48D,kka2_1:2_48,Kka2,kka2_1:2,P00552,,YES,48,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.453,-4.107,2.654,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.295029,0.00475422,0.374658 kka2_1:2_F48G,kka2_1:2_48,Kka2,kka2_1:2,P00552,,YES,48,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.453,-3.796,2.343,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.295029,0.00475422,0.435284 kka2_1:2_F48N,kka2_1:2_48,Kka2,kka2_1:2,P00552,,YES,48,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.453,-4.244,2.791,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.295029,0.00475422,0.362155 kka2_1:2_F48P,kka2_1:2_48,Kka2,kka2_1:2,P00552,,YES,48,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.453,-4.319,2.866,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.295029,0.00475422,0.415301 kka2_1:2_F48T,kka2_1:2_48,Kka2,kka2_1:2,P00552,,YES,48,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.453,-3.684,2.231,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.295029,0.00475422,0.446251 kka2_1:2_F48Y,kka2_1:2_48,Kka2,kka2_1:2,P00552,,YES,48,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.453,-1.946,0.493,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.295029,0.00475422,0.556828 kka2_1:2_G10Y,kka2_1:2_10,Kka2,kka2_1:2,P00552,,YES,10,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.921,-4.276,2.355,,,,,,,2.192,,71.59,HOP,-2.10733,0.295029,0.00289233,0.939641 kka2_1:2_G151H,kka2_1:2_151,Kka2,kka2_1:2,P00552,,YES,151,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.873,-4.645,3.772,,0.678,T,l,0.29,1.36,1.357,,49.62,HOH,-1.11433,0.295029,0.00339918,0.590527 kka2_1:2_G151P,kka2_1:2_151,Kka2,kka2_1:2,P00552,,YES,151,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.873,-3.953,3.08,,0.678,T,l,0.29,1.36,1.357,,49.62,HOH,-1.11433,0.295029,0.00339918,0.574127 kka2_1:2_G164M,kka2_1:2_164,Kka2,kka2_1:2,P00552,,YES,164,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.869,-4.95,4.081,,0.862,T,l,0.75,1.45,1.539,,64.39,POH,-1.828,0.295029,0.00442091,0.659603 kka2_1:2_G181M,kka2_1:2_181,Kka2,kka2_1:2,P00552,,YES,181,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-2.698,-4.828,2.13,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.295029,0.00728319,0.931527 kka2_1:2_G201T,kka2_1:2_201,Kka2,kka2_1:2,P00552,,YES,201,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.56,-3.028,1.468,,0.149,T,l,0.29,-0.57,16.092,16.092,52.65,POB,-1.92233,0.295029,0.00820117,0.530844 kka2_1:2_G205P,kka2_1:2_205,Kka2,kka2_1:2,P00552,,YES,205,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.596,-3.908,3.312,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.295029,0.00221855,0.442055 kka2_1:2_G21M,kka2_1:2_21,Kka2,kka2_1:2,P00552,,YES,21,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.368,-4.924,3.556,,0.586,T,l,0.29,-0.75,2.026,,71.59,HOH,-2.10167,0.295029,0.00709648,0.761045 kka2_1:2_G21P,kka2_1:2_21,Kka2,kka2_1:2,P00552,,YES,21,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.368,-3.965,2.597,,0.586,T,l,0.29,-0.75,2.026,,71.59,HOH,-2.10167,0.295029,0.00709648,0.681081 kka2_1:2_G21W,kka2_1:2_21,Kka2,kka2_1:2,P00552,,YES,21,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.368,-5.423,4.055,,0.586,T,l,0.29,-0.75,2.026,,71.59,HOH,-2.10167,0.295029,0.00709648,0.700402 kka2_1:2_G21Y,kka2_1:2_21,Kka2,kka2_1:2,P00552,,YES,21,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.368,-4.271,2.903,,0.586,T,l,0.29,-0.75,2.026,,71.59,HOH,-2.10167,0.295029,0.00709648,0.702058 kka2_1:2_G245I,kka2_1:2_245,Kka2,kka2_1:2,P00552,,YES,245,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.812,-4.212,3.4,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.295029,0.00683899,0.469003 kka2_1:2_G30K,kka2_1:2_30,Kka2,kka2_1:2,P00552,,YES,30,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.596,-3.71,3.114,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.295029,0.00159208,0.435385 kka2_1:2_G30M,kka2_1:2_30,Kka2,kka2_1:2,P00552,,YES,30,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.596,-4.958,4.362,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.295029,0.00159208,0.472335 kka2_1:2_G43H,kka2_1:2_43,Kka2,kka2_1:2,P00552,,YES,43,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.587,-4.654,3.067,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.295029,0.0071925,0.717737 kka2_1:2_G43L,kka2_1:2_43,Kka2,kka2_1:2,P00552,,YES,43,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.587,-3.778,2.191,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.295029,0.0071925,0.689541 kka2_1:2_G43N,kka2_1:2_43,Kka2,kka2_1:2,P00552,,YES,43,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.587,-2.611,1.024,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.295029,0.0071925,0.815884 kka2_1:2_G43Q,kka2_1:2_43,Kka2,kka2_1:2,P00552,,YES,43,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.587,-3.198,1.611,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.295029,0.0071925,0.762119 kka2_1:2_G55I,kka2_1:2_55,Kka2,kka2_1:2,P00552,,YES,55,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.625,-3.229,1.604,,0.517,S,b,0.75,1.19,15.753,15.753,63.64,POH,-2.05967,0.295029,0.00667877,0.628955 kka2_1:2_G55Y,kka2_1:2_55,Kka2,kka2_1:2,P00552,,YES,55,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.625,-4.276,2.651,,0.517,S,b,0.75,1.19,15.753,15.753,63.64,POH,-2.05967,0.295029,0.00667877,0.5762 kka2_1:2_G6I,kka2_1:2_6,Kka2,kka2_1:2,P00552,,YES,6,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.685,-3.841,2.156,,,,,,,,,71.59,AOH,-1.639,0.295029,0.00204693,1.04477 kka2_1:2_G88F,kka2_1:2_88,Kka2,kka2_1:2,P00552,,YES,88,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.689,-4.477,2.788,,0.54,S,l,0.75,1.51,2.814,,65.53,HOB,-1.718,0.295029,0.00685559,0.638832 kka2_1:2_G88H,kka2_1:2_88,Kka2,kka2_1:2,P00552,,YES,88,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.689,-3.199,1.51,,0.54,S,l,0.75,1.51,2.814,,65.53,HOB,-1.718,0.295029,0.00685559,0.675839 kka2_1:2_G88K,kka2_1:2_88,Kka2,kka2_1:2,P00552,,YES,88,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.689,-3.033,1.344,,0.54,S,l,0.75,1.51,2.814,,65.53,HOB,-1.718,0.295029,0.00685559,0.689857 kka2_1:2_G88M,kka2_1:2_88,Kka2,kka2_1:2,P00552,,YES,88,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.689,-4.913,3.224,,0.54,S,l,0.75,1.51,2.814,,65.53,HOB,-1.718,0.295029,0.00685559,0.661675 kka2_1:2_G88P,kka2_1:2_88,Kka2,kka2_1:2,P00552,,YES,88,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.689,-4.037,2.348,,0.54,S,l,0.75,1.51,2.814,,65.53,HOB,-1.718,0.295029,0.00685559,0.577623 kka2_1:2_G88Q,kka2_1:2_88,Kka2,kka2_1:2,P00552,,YES,88,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.689,-2.821,1.132,,0.54,S,l,0.75,1.51,2.814,,65.53,HOB,-1.718,0.295029,0.00685559,0.70573 kka2_1:2_G88W,kka2_1:2_88,Kka2,kka2_1:2,P00552,,YES,88,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.689,-5.544,3.855,,0.54,S,l,0.75,1.51,2.814,,65.53,HOB,-1.718,0.295029,0.00685559,0.643788 kka2_1:2_G99P,kka2_1:2_99,Kka2,kka2_1:2,P00552,,YES,99,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.596,-3.908,3.312,,0.368,S,g,0.29,-0.87,,,,OOP,-1.63067,0.295029,0.00186055,0.465912 kka2_1:2_H106C,kka2_1:2_106,Kka2,kka2_1:2,P00552,,YES,106,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-3.13,-5.214,2.084,,1.065,.,a,0.17,-0.95,2.53,,71.59,PBH,-2.10433,0.295029,0.00730778,0.87819 kka2_1:2_H106G,kka2_1:2_106,Kka2,kka2_1:2,P00552,,YES,106,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-3.13,-2.689,-0.441,,1.065,.,a,0.17,-0.95,2.53,,71.59,PBH,-2.10433,0.295029,0.00730778,0.922816 kka2_1:2_H106M,kka2_1:2_106,Kka2,kka2_1:2,P00552,,YES,106,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-3.13,-4.852,1.722,,1.065,.,a,0.17,-0.95,2.53,,71.59,PBH,-2.10433,0.295029,0.00730778,0.697043 kka2_1:2_H106S,kka2_1:2_106,Kka2,kka2_1:2,P00552,,YES,106,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-3.13,-2.484,-0.646,,1.065,.,a,0.17,-0.95,2.53,,71.59,PBH,-2.10433,0.295029,0.00730778,0.943662 kka2_1:2_H106T,kka2_1:2_106,Kka2,kka2_1:2,P00552,,YES,106,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-3.13,-2.51,-0.62,,1.065,.,a,0.17,-0.95,2.53,,71.59,PBH,-2.10433,0.295029,0.00730778,0.945135 kka2_1:2_H124A,kka2_1:2_124,Kka2,kka2_1:2,P00552,,YES,124,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-0.84,-3.331,2.491,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.295029,0.00211296,0.429197 kka2_1:2_H124C,kka2_1:2_124,Kka2,kka2_1:2,P00552,,YES,124,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-0.84,-5.115,4.275,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.295029,0.00211296,0.462053 kka2_1:2_H124E,kka2_1:2_124,Kka2,kka2_1:2,P00552,,YES,124,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-0.84,-3.243,2.403,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.295029,0.00211296,0.453287 kka2_1:2_H124F,kka2_1:2_124,Kka2,kka2_1:2,P00552,,YES,124,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-0.84,-3.87,3.03,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.295029,0.00211296,0.425668 kka2_1:2_H124L,kka2_1:2_124,Kka2,kka2_1:2,P00552,,YES,124,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-0.84,-3.611,2.771,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.295029,0.00211296,0.446499 kka2_1:2_H124M,kka2_1:2_124,Kka2,kka2_1:2,P00552,,YES,124,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-0.84,-4.733,3.893,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.295029,0.00211296,0.449099 kka2_1:2_H124S,kka2_1:2_124,Kka2,kka2_1:2,P00552,,YES,124,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-0.84,-3.414,2.574,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.295029,0.00211296,0.455974 kka2_1:2_H124V,kka2_1:2_124,Kka2,kka2_1:2,P00552,,YES,124,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-0.84,-3.782,2.942,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.295029,0.00211296,0.433872 kka2_1:2_H124W,kka2_1:2_124,Kka2,kka2_1:2,P00552,,YES,124,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-0.84,-5.126,4.286,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.295029,0.00211296,0.407555 kka2_1:2_H139A,kka2_1:2_139,Kka2,kka2_1:2,P00552,,YES,139,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-2.809,-2.449,-0.36,,0.471,H,A,0.87,0.68,13.912,13.912,63.64,BBB,-2.22,0.295029,0.00734779,0.904947 kka2_1:2_H139E,kka2_1:2_139,Kka2,kka2_1:2,P00552,,YES,139,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-2.809,-2.979,0.17,,0.471,H,A,0.87,0.68,13.912,13.912,63.64,BBB,-2.22,0.295029,0.00734779,0.842976 kka2_1:2_H139M,kka2_1:2_139,Kka2,kka2_1:2,P00552,,YES,139,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-2.809,-3.708,0.899,,0.471,H,A,0.87,0.68,13.912,13.912,63.64,BBB,-2.22,0.295029,0.00734779,0.759789 kka2_1:2_H139V,kka2_1:2_139,Kka2,kka2_1:2,P00552,,YES,139,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-2.809,-2.837,0.028,,0.471,H,A,0.87,0.68,13.912,13.912,63.64,BBB,-2.22,0.295029,0.00734779,0.851778 kka2_1:2_H139W,kka2_1:2_139,Kka2,kka2_1:2,P00552,,YES,139,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-2.809,-5.517,2.708,,0.471,H,A,0.87,0.68,13.912,13.912,63.64,BBB,-2.22,0.295029,0.00734779,0.845366 kka2_1:2_H162A,kka2_1:2_162,Kka2,kka2_1:2,P00552,,YES,162,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-2.319,-3.316,0.997,,0.071,G,A,0.17,1.01,3.187,,64.39,ABP,-2.02067,0.295029,0.00616145,0.486333 kka2_1:2_H162G,kka2_1:2_162,Kka2,kka2_1:2,P00552,,YES,162,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-2.319,-3.406,1.087,,0.071,G,A,0.17,1.01,3.187,,64.39,ABP,-2.02067,0.295029,0.00616145,0.475052 kka2_1:2_H162S,kka2_1:2_162,Kka2,kka2_1:2,P00552,,YES,162,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-2.319,-3.471,1.152,,0.071,G,A,0.17,1.01,3.187,,64.39,ABP,-2.02067,0.295029,0.00616145,0.509614 kka2_1:2_H162T,kka2_1:2_162,Kka2,kka2_1:2,P00552,,YES,162,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-2.319,-3.571,1.252,,0.071,G,A,0.17,1.01,3.187,,64.39,ABP,-2.02067,0.295029,0.00616145,0.486591 kka2_1:2_H162W,kka2_1:2_162,Kka2,kka2_1:2,P00552,,YES,162,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-2.319,-2.828,0.509,,0.071,G,A,0.17,1.01,3.187,,64.39,ABP,-2.02067,0.295029,0.00616145,0.595442 kka2_1:2_H8M,kka2_1:2_8,Kka2,kka2_1:2,P00552,,YES,8,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-2.759,-4.438,1.679,,,,,,,,,71.59,HBH,-2.25467,0.295029,0.00256422,1.02057 kka2_1:2_H8P,kka2_1:2_8,Kka2,kka2_1:2,P00552,,YES,8,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-2.759,-3.809,1.05,,,,,,,,,71.59,HBH,-2.25467,0.295029,0.00256422,0.960864 kka2_1:2_H8S,kka2_1:2_8,Kka2,kka2_1:2,P00552,,YES,8,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-2.759,-2.388,-0.371,,,,,,,,,71.59,HBH,-2.25467,0.295029,0.00256422,1.05279 kka2_1:2_I141A,kka2_1:2_141,Kka2,kka2_1:2,P00552,,YES,141,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.495,-3.207,1.712,,0.068,H,A,0.48,-0.01,0.819,,92.05,BHA,-1.689,0.295029,0.00744745,0.448013 kka2_1:2_I141G,kka2_1:2_141,Kka2,kka2_1:2,P00552,,YES,141,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.495,-3.916,2.421,,0.068,H,A,0.48,-0.01,0.819,,92.05,BHA,-1.689,0.295029,0.00744745,0.515356 kka2_1:2_I141P,kka2_1:2_141,Kka2,kka2_1:2,P00552,,YES,141,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.495,-4.213,2.718,,0.068,H,A,0.48,-0.01,0.819,,92.05,BHA,-1.689,0.295029,0.00744745,0.506377 kka2_1:2_I141R,kka2_1:2_141,Kka2,kka2_1:2,P00552,,YES,141,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.495,-4.204,2.709,,0.068,H,A,0.48,-0.01,0.819,,92.05,BHA,-1.689,0.295029,0.00744745,0.548477 kka2_1:2_I141W,kka2_1:2_141,Kka2,kka2_1:2,P00552,,YES,141,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.495,-5.368,3.873,,0.068,H,A,0.48,-0.01,0.819,,92.05,BHA,-1.689,0.295029,0.00744745,0.470938 kka2_1:2_I221A,kka2_1:2_221,Kka2,kka2_1:2,P00552,,YES,221,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.739,-3.216,1.477,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.295029,0.00945908,0.473475 kka2_1:2_I246D,kka2_1:2_246,Kka2,kka2_1:2,P00552,,YES,246,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-2.008,-3.218,1.21,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.295029,0.0139479,0.572271 kka2_1:2_I246F,kka2_1:2_246,Kka2,kka2_1:2,P00552,,YES,246,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-2.008,-3.274,1.266,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.295029,0.0139479,0.581035 kka2_1:2_I246G,kka2_1:2_246,Kka2,kka2_1:2,P00552,,YES,246,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-2.008,-2.463,0.455,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.295029,0.0139479,0.720992 kka2_1:2_I246Q,kka2_1:2_246,Kka2,kka2_1:2,P00552,,YES,246,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-2.008,-4.292,2.284,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.295029,0.0139479,0.689669 kka2_1:2_I246W,kka2_1:2_246,Kka2,kka2_1:2,P00552,,YES,246,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-2.008,-5.452,3.444,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.295029,0.0139479,0.649654 kka2_1:2_I254R,kka2_1:2_254,Kka2,kka2_1:2,P00552,,YES,254,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.933,-3.154,1.221,,0.135,H,A,1.52,-0.6,2.562,,71.59,BHH,-1.668,0.295029,0.0132375,0.522938 kka2_1:2_I29C,kka2_1:2_29,Kka2,kka2_1:2,P00552,,YES,29,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.692,-4.988,3.296,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.295029,0.00619521,0.706131 kka2_1:2_I29E,kka2_1:2_29,Kka2,kka2_1:2,P00552,,YES,29,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.692,-2.793,1.101,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.295029,0.00619521,0.784862 kka2_1:2_I29G,kka2_1:2_29,Kka2,kka2_1:2,P00552,,YES,29,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.692,-2.967,1.275,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.295029,0.00619521,0.789246 kka2_1:2_I29P,kka2_1:2_29,Kka2,kka2_1:2,P00552,,YES,29,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.692,-4.154,2.462,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.295029,0.00619521,0.629387 kka2_1:2_I29W,kka2_1:2_29,Kka2,kka2_1:2,P00552,,YES,29,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.692,-5.447,3.755,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.295029,0.00619521,0.660386 kka2_1:2_I2A,kka2_1:2_2,Kka2,kka2_1:2,P00552,,YES,2,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.787,-2.783,0.996,,,,,,,5.773,,71.59,HHA,-1.92433,0.295029,0.00246644,0.958248 kka2_1:2_K112A,kka2_1:2_112,Kka2,kka2_1:2,P00552,,YES,112,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-2.491,-2.624,0.133,,0.076,H,A,2.34,-1.37,23.433,23.433,56.06,ABH,-2.00133,0.295029,0.00645389,0.573148 kka2_1:2_K112G,kka2_1:2_112,Kka2,kka2_1:2,P00552,,YES,112,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-2.491,-3.699,1.208,,0.076,H,A,2.34,-1.37,23.433,23.433,56.06,ABH,-2.00133,0.295029,0.00645389,0.4705 kka2_1:2_K112V,kka2_1:2_112,Kka2,kka2_1:2,P00552,,YES,112,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-2.491,-2.276,-0.215,,0.076,H,A,2.34,-1.37,23.433,23.433,56.06,ABH,-2.00133,0.295029,0.00645389,0.626651 kka2_1:2_K138A,kka2_1:2_138,Kka2,kka2_1:2,P00552,,YES,138,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-2.5,-2.407,-0.093,,0.594,H,A,2.34,0.98,21.038,21.038,71.59,HBB,-2.48833,0.295029,0.00628542,0.881556 kka2_1:2_K138P,kka2_1:2_138,Kka2,kka2_1:2,P00552,,YES,138,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-2.5,-3.19,0.69,,0.594,H,A,2.34,0.98,21.038,21.038,71.59,HBB,-2.48833,0.295029,0.00628542,0.753621 kka2_1:2_K175F,kka2_1:2_175,Kka2,kka2_1:2,P00552,,YES,175,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-2.897,-4.186,1.289,,0.579,H,A,1.3,0.51,15.629,15.629,71.59,HBH,-1.82333,0.295029,0.00693093,0.792532 kka2_1:2_K175L,kka2_1:2_175,Kka2,kka2_1:2,P00552,,YES,175,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-2.897,-1.898,-0.999,,0.579,H,A,1.3,0.51,15.629,15.629,71.59,HBH,-1.82333,0.295029,0.00693093,0.978452 kka2_1:2_K175W,kka2_1:2_175,Kka2,kka2_1:2,P00552,,YES,175,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-2.897,-5.429,2.532,,0.579,H,A,1.3,0.51,15.629,15.629,71.59,HBH,-1.82333,0.295029,0.00693093,0.840232 kka2_1:2_K50C,kka2_1:2_50,Kka2,kka2_1:2,P00552,,YES,50,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-0.833,-5.139,4.306,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.295029,0.00138626,0.502108 kka2_1:2_K50F,kka2_1:2_50,Kka2,kka2_1:2,P00552,,YES,50,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-0.833,-4.344,3.511,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.295029,0.00138626,0.420216 kka2_1:2_K50G,kka2_1:2_50,Kka2,kka2_1:2,P00552,,YES,50,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-0.833,-3.41,2.577,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.295029,0.00138626,0.501341 kka2_1:2_K50M,kka2_1:2_50,Kka2,kka2_1:2,P00552,,YES,50,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-0.833,-4.531,3.698,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.295029,0.00138626,0.432874 kka2_1:2_K50P,kka2_1:2_50,Kka2,kka2_1:2,P00552,,YES,50,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-0.833,-3.727,2.894,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.295029,0.00138626,0.462259 kka2_1:2_K50W,kka2_1:2_50,Kka2,kka2_1:2,P00552,,YES,50,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-0.833,-5.374,4.541,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.295029,0.00138626,0.393929 kka2_1:2_K50Y,kka2_1:2_50,Kka2,kka2_1:2,P00552,,YES,50,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-0.833,-4.214,3.381,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.295029,0.00138626,0.435214 kka2_1:2_L102A,kka2_1:2_102,Kka2,kka2_1:2,P00552,,YES,102,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.804,-3.129,2.325,,,T,A,1.59,-1.17,4.258,,42.42,AHH,-1.398,0.295029,0.00201332,0.451895 kka2_1:2_L102G,kka2_1:2_102,Kka2,kka2_1:2,P00552,,YES,102,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.804,-3.835,3.031,,,T,A,1.59,-1.17,4.258,,42.42,AHH,-1.398,0.295029,0.00201332,0.413985 kka2_1:2_L102K,kka2_1:2_102,Kka2,kka2_1:2,P00552,,YES,102,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.804,-3.708,2.904,,,T,A,1.59,-1.17,4.258,,42.42,AHH,-1.398,0.295029,0.00201332,0.376287 kka2_1:2_L102N,kka2_1:2_102,Kka2,kka2_1:2,P00552,,YES,102,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.804,-4.149,3.345,,,T,A,1.59,-1.17,4.258,,42.42,AHH,-1.398,0.295029,0.00201332,0.374798 kka2_1:2_L102T,kka2_1:2_102,Kka2,kka2_1:2,P00552,,YES,102,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.804,-3.473,2.669,,,T,A,1.59,-1.17,4.258,,42.42,AHH,-1.398,0.295029,0.00201332,0.442037 kka2_1:2_L102W,kka2_1:2_102,Kka2,kka2_1:2,P00552,,YES,102,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.804,-5.124,4.32,,,T,A,1.59,-1.17,4.258,,42.42,AHH,-1.398,0.295029,0.00201332,0.356298 kka2_1:2_L103E,kka2_1:2_103,Kka2,kka2_1:2,P00552,,YES,103,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-2.362,-2.689,0.327,,0.394,T,A,0.55,-0.99,3.499,,63.64,HHP,-1.534,0.295029,0.00574792,0.605189 kka2_1:2_L103S,kka2_1:2_103,Kka2,kka2_1:2,P00552,,YES,103,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-2.362,-2.565,0.203,,0.394,T,A,0.55,-0.99,3.499,,63.64,HHP,-1.534,0.295029,0.00574792,0.640559 kka2_1:2_L103Y,kka2_1:2_103,Kka2,kka2_1:2,P00552,,YES,103,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-2.362,-4.297,1.935,,0.394,T,A,0.55,-0.99,3.499,,63.64,HHP,-1.534,0.295029,0.00574792,0.621215 kka2_1:2_L107G,kka2_1:2_107,Kka2,kka2_1:2,P00552,,YES,107,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.238,-3.822,2.584,,0.197,,B,1.59,-1.1,2.68,,71.59,BHH,-2.143,0.295029,0.00561937,0.454559 kka2_1:2_L123C,kka2_1:2_123,Kka2,kka2_1:2,P00552,,YES,123,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.888,-4.72,3.832,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.295029,0.00325188,0.513044 kka2_1:2_L123D,kka2_1:2_123,Kka2,kka2_1:2,P00552,,YES,123,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.888,-4.173,3.285,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.295029,0.00325188,0.41184 kka2_1:2_L123E,kka2_1:2_123,Kka2,kka2_1:2,P00552,,YES,123,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.888,-3.94,3.052,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.295029,0.00325188,0.394101 kka2_1:2_L123F,kka2_1:2_123,Kka2,kka2_1:2,P00552,,YES,123,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.888,-3.7,2.812,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.295029,0.00325188,0.390504 kka2_1:2_L123G,kka2_1:2_123,Kka2,kka2_1:2,P00552,,YES,123,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.888,-3.859,2.971,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.295029,0.00325188,0.462822 kka2_1:2_L123K,kka2_1:2_123,Kka2,kka2_1:2,P00552,,YES,123,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.888,-3.75,2.862,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.295029,0.00325188,0.4009 kka2_1:2_L123N,kka2_1:2_123,Kka2,kka2_1:2,P00552,,YES,123,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.888,-4.173,3.285,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.295029,0.00325188,0.391477 kka2_1:2_L123T,kka2_1:2_123,Kka2,kka2_1:2,P00552,,YES,123,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.888,-3.505,2.617,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.295029,0.00325188,0.47193 kka2_1:2_L123Y,kka2_1:2_123,Kka2,kka2_1:2,P00552,,YES,123,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.888,-4.021,3.133,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.295029,0.00325188,0.394877 kka2_1:2_L126C,kka2_1:2_126,Kka2,kka2_1:2,P00552,,YES,126,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.246,-4.83,3.584,,0.285,S,B,0.55,0.12,1.392,,51.89,PHA,-1.744,0.295029,0.0066485,0.564713 kka2_1:2_L126D,kka2_1:2_126,Kka2,kka2_1:2,P00552,,YES,126,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.246,-4.074,2.828,,0.285,S,B,0.55,0.12,1.392,,51.89,PHA,-1.744,0.295029,0.0066485,0.422353 kka2_1:2_L126K,kka2_1:2_126,Kka2,kka2_1:2,P00552,,YES,126,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.246,-3.81,2.564,,0.285,S,B,0.55,0.12,1.392,,51.89,PHA,-1.744,0.295029,0.0066485,0.429765 kka2_1:2_L126N,kka2_1:2_126,Kka2,kka2_1:2,P00552,,YES,126,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.246,-4.157,2.911,,0.285,S,B,0.55,0.12,1.392,,51.89,PHA,-1.744,0.295029,0.0066485,0.428103 kka2_1:2_L126T,kka2_1:2_126,Kka2,kka2_1:2,P00552,,YES,126,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.246,-2.585,1.339,,0.285,S,B,0.55,0.12,1.392,,51.89,PHA,-1.744,0.295029,0.0066485,0.53298 kka2_1:2_L126Y,kka2_1:2_126,Kka2,kka2_1:2,P00552,,YES,126,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.246,-4.126,2.88,,0.285,S,B,0.55,0.12,1.392,,51.89,PHA,-1.744,0.295029,0.0066485,0.462455 kka2_1:2_L152A,kka2_1:2_152,Kka2,kka2_1:2,P00552,,YES,152,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.521,-2.279,0.758,,0.547,.,A,0.55,1.36,4.526,,63.64,OHH,-1.162,0.295029,0.00674868,0.694865 kka2_1:2_L152C,kka2_1:2_152,Kka2,kka2_1:2,P00552,,YES,152,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.521,-4.941,3.42,,0.547,.,A,0.55,1.36,4.526,,63.64,OHH,-1.162,0.295029,0.00674868,0.657766 kka2_1:2_L152G,kka2_1:2_152,Kka2,kka2_1:2,P00552,,YES,152,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.521,-3.713,2.192,,0.547,.,A,0.55,1.36,4.526,,63.64,OHH,-1.162,0.295029,0.00674868,0.640939 kka2_1:2_L152S,kka2_1:2_152,Kka2,kka2_1:2,P00552,,YES,152,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.521,-3.591,2.07,,0.547,.,A,0.55,1.36,4.526,,63.64,OHH,-1.162,0.295029,0.00674868,0.654038 kka2_1:2_L152Y,kka2_1:2_152,Kka2,kka2_1:2,P00552,,YES,152,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.521,-4.238,2.717,,0.547,.,A,0.55,1.36,4.526,,63.64,OHH,-1.162,0.295029,0.00674868,0.571367 kka2_1:2_L158C,kka2_1:2_158,Kka2,kka2_1:2,P00552,,YES,158,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.947,-4.909,2.962,,0.095,,B,1.59,0.77,7.588,,63.64,AHA,-1.25333,0.295029,0.00529068,0.652337 kka2_1:2_L158S,kka2_1:2_158,Kka2,kka2_1:2,P00552,,YES,158,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.947,-3.691,1.744,,0.095,,B,1.59,0.77,7.588,,63.64,AHA,-1.25333,0.295029,0.00529068,0.51178 kka2_1:2_L158T,kka2_1:2_158,Kka2,kka2_1:2,P00552,,YES,158,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.947,-3.635,1.688,,0.095,,B,1.59,0.77,7.588,,63.64,AHA,-1.25333,0.295029,0.00529068,0.510454 kka2_1:2_L165W,kka2_1:2_165,Kka2,kka2_1:2,P00552,,YES,165,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-2.453,-3.283,0.83,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.295029,0.00801161,0.780875 kka2_1:2_L170D,kka2_1:2_170,Kka2,kka2_1:2,P00552,,YES,170,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.28,-4.131,2.851,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.295029,0.00730791,0.444709 kka2_1:2_L174W,kka2_1:2_174,Kka2,kka2_1:2,P00552,,YES,174,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.952,-5.22,4.268,,,H,A,1.59,-0.31,8.521,,51.89,BHB,-2.08533,0.295029,0.00438501,0.40436 kka2_1:2_L19A,kka2_1:2_19,Kka2,kka2_1:2,P00552,,YES,19,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.254,-3.301,2.047,,0.08,T,A,0.55,-0.26,17.165,17.165,65.53,BHH,-2.221,0.295029,0.00620703,0.464565 kka2_1:2_L19D,kka2_1:2_19,Kka2,kka2_1:2,P00552,,YES,19,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.254,-4.151,2.897,,0.08,T,A,0.55,-0.26,17.165,17.165,65.53,BHH,-2.221,0.295029,0.00620703,0.460621 kka2_1:2_L19E,kka2_1:2_19,Kka2,kka2_1:2,P00552,,YES,19,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.254,-3.966,2.712,,0.08,T,A,0.55,-0.26,17.165,17.165,65.53,BHH,-2.221,0.295029,0.00620703,0.457289 kka2_1:2_L19Y,kka2_1:2_19,Kka2,kka2_1:2,P00552,,YES,19,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.254,-2.672,1.418,,0.08,T,A,0.55,-0.26,17.165,17.165,65.53,BHH,-2.221,0.295029,0.00620703,0.646274 kka2_1:2_L212G,kka2_1:2_212,Kka2,kka2_1:2,P00552,,YES,212,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.904,-3.697,2.793,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.295029,0.0031426,0.479837 kka2_1:2_L223E,kka2_1:2_223,Kka2,kka2_1:2,P00552,,YES,223,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.861,-3.963,3.102,,,H,A,0.55,-1.24,0.266,,50,HHH,-0.854333,0.295029,0.00253574,0.378513 kka2_1:2_L241A,kka2_1:2_241,Kka2,kka2_1:2,P00552,,YES,241,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.158,-3.226,2.068,,0.08,H,A,0.55,-0.82,1.598,,63.26,HHH,-1.58533,0.295029,0.0117299,0.454828 kka2_1:2_L241S,kka2_1:2_241,Kka2,kka2_1:2,P00552,,YES,241,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.158,-3.689,2.531,,0.08,H,A,0.55,-0.82,1.598,,63.26,HHH,-1.58533,0.295029,0.0117299,0.464496 kka2_1:2_L243D,kka2_1:2_243,Kka2,kka2_1:2,P00552,,YES,243,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-2.651,-3.837,1.186,,0.277,H,A,1.59,-0.67,13.165,13.165,92.05,HHH,-2.03767,0.295029,0.00884927,0.63343 kka2_1:2_L243S,kka2_1:2_243,Kka2,kka2_1:2,P00552,,YES,243,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-2.651,-2.842,0.191,,0.277,H,A,1.59,-0.67,13.165,13.165,92.05,HHH,-2.03767,0.295029,0.00884927,0.83148 kka2_1:2_L260Y,kka2_1:2_260,Kka2,kka2_1:2,P00552,,YES,260,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.741,-3.966,3.225,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.295029,0.0233782,0.355748 kka2_1:2_L39C,kka2_1:2_39,Kka2,kka2_1:2,P00552,,YES,39,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.223,-4.817,3.594,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.295029,0.00493618,0.532221 kka2_1:2_L39F,kka2_1:2_39,Kka2,kka2_1:2,P00552,,YES,39,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.223,-2.955,1.732,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.295029,0.00493618,0.533679 kka2_1:2_L39S,kka2_1:2_39,Kka2,kka2_1:2,P00552,,YES,39,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.223,-3.678,2.455,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.295029,0.00493618,0.457564 kka2_1:2_L39T,kka2_1:2_39,Kka2,kka2_1:2,P00552,,YES,39,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.223,-3.551,2.328,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.295029,0.00493618,0.50111 kka2_1:2_L39Y,kka2_1:2_39,Kka2,kka2_1:2,P00552,,YES,39,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.223,-4.042,2.819,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.295029,0.00493618,0.416253 kka2_1:2_L53A,kka2_1:2_53,Kka2,kka2_1:2,P00552,,YES,53,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-2.681,-2.486,-0.195,,0.569,E,B,0.55,0.8,19.536,19.536,71.59,AHP,-2.47433,0.295029,0.00671168,0.948255 kka2_1:2_L53G,kka2_1:2_53,Kka2,kka2_1:2,P00552,,YES,53,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-2.681,-3.649,0.968,,0.569,E,B,0.55,0.8,19.536,19.536,71.59,AHP,-2.47433,0.295029,0.00671168,0.796548 kka2_1:2_L53N,kka2_1:2_53,Kka2,kka2_1:2,P00552,,YES,53,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-2.681,-3.274,0.593,,0.569,E,B,0.55,0.8,19.536,19.536,71.59,AHP,-2.47433,0.295029,0.00671168,0.852888 kka2_1:2_L53T,kka2_1:2_53,Kka2,kka2_1:2,P00552,,YES,53,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-2.681,-3.105,0.424,,0.569,E,B,0.55,0.8,19.536,19.536,71.59,AHP,-2.47433,0.295029,0.00671168,0.823516 kka2_1:2_L53W,kka2_1:2_53,Kka2,kka2_1:2,P00552,,YES,53,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-2.681,-5.633,2.952,,0.569,E,B,0.55,0.8,19.536,19.536,71.59,AHP,-2.47433,0.295029,0.00671168,0.864392 kka2_1:2_L57C,kka2_1:2_57,Kka2,kka2_1:2,P00552,,YES,57,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.898,-5.037,3.139,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.295029,0.00723769,0.597867 kka2_1:2_L57F,kka2_1:2_57,Kka2,kka2_1:2,P00552,,YES,57,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.898,-1.677,-0.221,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.295029,0.00723769,0.76753 kka2_1:2_L57G,kka2_1:2_57,Kka2,kka2_1:2,P00552,,YES,57,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.898,-3.786,1.888,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.295029,0.00723769,0.485808 kka2_1:2_L57S,kka2_1:2_57,Kka2,kka2_1:2,P00552,,YES,57,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.898,-3.77,1.872,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.295029,0.00723769,0.491058 kka2_1:2_L57Y,kka2_1:2_57,Kka2,kka2_1:2,P00552,,YES,57,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.898,-2.955,1.057,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.295029,0.00723769,0.57179 kka2_1:2_L60E,kka2_1:2_60,Kka2,kka2_1:2,P00552,,YES,60,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.997,-3.964,2.967,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.295029,0.00262176,0.455153 kka2_1:2_L60F,kka2_1:2_60,Kka2,kka2_1:2,P00552,,YES,60,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.997,-2.839,1.842,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.295029,0.00262176,0.518066 kka2_1:2_L60N,kka2_1:2_60,Kka2,kka2_1:2,P00552,,YES,60,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.997,-4.225,3.228,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.295029,0.00262176,0.434179 kka2_1:2_L60T,kka2_1:2_60,Kka2,kka2_1:2,P00552,,YES,60,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.997,-3.529,2.532,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.295029,0.00262176,0.48634 kka2_1:2_L60W,kka2_1:2_60,Kka2,kka2_1:2,P00552,,YES,60,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.997,-5.166,4.169,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.295029,0.00262176,0.412464 kka2_1:2_L60Y,kka2_1:2_60,Kka2,kka2_1:2,P00552,,YES,60,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.997,-3.955,2.958,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.295029,0.00262176,0.462418 kka2_1:2_L67C,kka2_1:2_67,Kka2,kka2_1:2,P00552,,YES,67,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.741,-4.665,3.924,,0.007,H,A,1.59,-0.66,,,,BHP,-1.42867,0.295029,0.00102787,0.439635 kka2_1:2_L67E,kka2_1:2_67,Kka2,kka2_1:2,P00552,,YES,67,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.741,-3.918,3.177,,0.007,H,A,1.59,-0.66,,,,BHP,-1.42867,0.295029,0.00102787,0.352187 kka2_1:2_L67G,kka2_1:2_67,Kka2,kka2_1:2,P00552,,YES,67,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.741,-3.836,3.095,,0.007,H,A,1.59,-0.66,,,,BHP,-1.42867,0.295029,0.00102787,0.401183 kka2_1:2_L67H,kka2_1:2_67,Kka2,kka2_1:2,P00552,,YES,67,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.741,-4.933,4.192,,0.007,H,A,1.59,-0.66,,,,BHP,-1.42867,0.295029,0.00102787,0.377399 kka2_1:2_L67I,kka2_1:2_67,Kka2,kka2_1:2,P00552,,YES,67,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.741,-2.914,2.173,,0.007,H,A,1.59,-0.66,,,,BHP,-1.42867,0.295029,0.00102787,0.448337 kka2_1:2_L67K,kka2_1:2_67,Kka2,kka2_1:2,P00552,,YES,67,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.741,-3.71,2.969,,0.007,H,A,1.59,-0.66,,,,BHP,-1.42867,0.295029,0.00102787,0.353689 kka2_1:2_L67N,kka2_1:2_67,Kka2,kka2_1:2,P00552,,YES,67,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.741,-4.151,3.41,,0.007,H,A,1.59,-0.66,,,,BHP,-1.42867,0.295029,0.00102787,0.352015 kka2_1:2_L67Q,kka2_1:2_67,Kka2,kka2_1:2,P00552,,YES,67,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.741,-4.153,3.412,,0.007,H,A,1.59,-0.66,,,,BHP,-1.42867,0.295029,0.00102787,0.359565 kka2_1:2_L67T,kka2_1:2_67,Kka2,kka2_1:2,P00552,,YES,67,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.741,-3.45,2.709,,0.007,H,A,1.59,-0.66,,,,BHP,-1.42867,0.295029,0.00102787,0.420456 kka2_1:2_L70D,kka2_1:2_70,Kka2,kka2_1:2,P00552,,YES,70,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.017,-4.187,3.17,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.295029,0.00411884,0.404881 kka2_1:2_L70E,kka2_1:2_70,Kka2,kka2_1:2,P00552,,YES,70,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.017,-3.949,2.932,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.295029,0.00411884,0.395813 kka2_1:2_L70G,kka2_1:2_70,Kka2,kka2_1:2,P00552,,YES,70,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.017,-3.868,2.851,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.295029,0.00411884,0.444047 kka2_1:2_L70H,kka2_1:2_70,Kka2,kka2_1:2,P00552,,YES,70,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.017,-4.982,3.965,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.295029,0.00411884,0.415054 kka2_1:2_L70N,kka2_1:2_70,Kka2,kka2_1:2,P00552,,YES,70,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.017,-4.199,3.182,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.295029,0.00411884,0.394994 kka2_1:2_L70S,kka2_1:2_70,Kka2,kka2_1:2,P00552,,YES,70,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.017,-3.687,2.67,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.295029,0.00411884,0.445366 kka2_1:2_L70T,kka2_1:2_70,Kka2,kka2_1:2,P00552,,YES,70,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.017,-3.534,2.517,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.295029,0.00411884,0.453943 kka2_1:2_L70W,kka2_1:2_70,Kka2,kka2_1:2,P00552,,YES,70,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.017,-5.201,4.184,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.295029,0.00411884,0.390925 kka2_1:2_L70Y,kka2_1:2_70,Kka2,kka2_1:2,P00552,,YES,70,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.017,-4.068,3.051,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.295029,0.00411884,0.401877 kka2_1:2_L7E,kka2_1:2_7,Kka2,kka2_1:2,P00552,,YES,7,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.926,-3.32,1.394,,,,,,,3.012,,71.59,OHB,-2.12333,0.295029,0.00269456,0.990359 kka2_1:2_L7G,kka2_1:2_7,Kka2,kka2_1:2,P00552,,YES,7,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.926,-2.13,0.204,,,,,,,3.012,,71.59,OHB,-2.12333,0.295029,0.00269456,0.955638 kka2_1:2_L7T,kka2_1:2_7,Kka2,kka2_1:2,P00552,,YES,7,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.926,-3.425,1.499,,,,,,,3.012,,71.59,OHB,-2.12333,0.295029,0.00269456,1.00932 kka2_1:2_L81A,kka2_1:2_81,Kka2,kka2_1:2,P00552,,YES,81,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.427,-3.213,1.786,,0.46,E,A,1.59,-0.14,1.895,,63.64,HHA,-1.50567,0.295029,0.00805839,0.572148 kka2_1:2_L81C,kka2_1:2_81,Kka2,kka2_1:2,P00552,,YES,81,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.427,-4.845,3.418,,0.46,E,A,1.59,-0.14,1.895,,63.64,HHA,-1.50567,0.295029,0.00805839,0.724682 kka2_1:2_L81D,kka2_1:2_81,Kka2,kka2_1:2,P00552,,YES,81,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.427,-4.125,2.698,,0.46,E,A,1.59,-0.14,1.895,,63.64,HHA,-1.50567,0.295029,0.00805839,0.618133 kka2_1:2_L81E,kka2_1:2_81,Kka2,kka2_1:2,P00552,,YES,81,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.427,-3.901,2.474,,0.46,E,A,1.59,-0.14,1.895,,63.64,HHA,-1.50567,0.295029,0.00805839,0.621394 kka2_1:2_L81F,kka2_1:2_81,Kka2,kka2_1:2,P00552,,YES,81,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.427,-3.878,2.451,,0.46,E,A,1.59,-0.14,1.895,,63.64,HHA,-1.50567,0.295029,0.00805839,0.631507 kka2_1:2_L81G,kka2_1:2_81,Kka2,kka2_1:2,P00552,,YES,81,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.427,-3.894,2.467,,0.46,E,A,1.59,-0.14,1.895,,63.64,HHA,-1.50567,0.295029,0.00805839,0.640863 kka2_1:2_L81H,kka2_1:2_81,Kka2,kka2_1:2,P00552,,YES,81,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.427,-5.02,3.593,,0.46,E,A,1.59,-0.14,1.895,,63.64,HHA,-1.50567,0.295029,0.00805839,0.664511 kka2_1:2_L81S,kka2_1:2_81,Kka2,kka2_1:2,P00552,,YES,81,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.427,-3.746,2.319,,0.46,E,A,1.59,-0.14,1.895,,63.64,HHA,-1.50567,0.295029,0.00805839,0.65069 kka2_1:2_L81T,kka2_1:2_81,Kka2,kka2_1:2,P00552,,YES,81,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.427,-3.556,2.129,,0.46,E,A,1.59,-0.14,1.895,,63.64,HHA,-1.50567,0.295029,0.00805839,0.642755 kka2_1:2_L81Y,kka2_1:2_81,Kka2,kka2_1:2,P00552,,YES,81,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.427,-4.125,2.698,,0.46,E,A,1.59,-0.14,1.895,,63.64,HHA,-1.50567,0.295029,0.00805839,0.647958 kka2_1:2_L92A,kka2_1:2_92,Kka2,kka2_1:2,P00552,,YES,92,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.893,-3.128,2.235,,0.007,E,B,1.59,-0.19,1.447,,63.26,HHH,-0.962,0.295029,0.00307177,0.45306 kka2_1:2_L92C,kka2_1:2_92,Kka2,kka2_1:2,P00552,,YES,92,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.893,-4.72,3.827,,0.007,E,B,1.59,-0.19,1.447,,63.26,HHH,-0.962,0.295029,0.00307177,0.562607 kka2_1:2_L92D,kka2_1:2_92,Kka2,kka2_1:2,P00552,,YES,92,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.893,-4.173,3.28,,0.007,E,B,1.59,-0.19,1.447,,63.26,HHH,-0.962,0.295029,0.00307177,0.40384 kka2_1:2_L92G,kka2_1:2_92,Kka2,kka2_1:2,P00552,,YES,92,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.893,-3.838,2.945,,0.007,E,B,1.59,-0.19,1.447,,63.26,HHH,-0.962,0.295029,0.00307177,0.46317 kka2_1:2_L92I,kka2_1:2_92,Kka2,kka2_1:2,P00552,,YES,92,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.893,-2.953,2.06,,0.007,E,B,1.59,-0.19,1.447,,63.26,HHH,-0.962,0.295029,0.00307177,0.464629 kka2_1:2_L92K,kka2_1:2_92,Kka2,kka2_1:2,P00552,,YES,92,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.893,-3.743,2.85,,0.007,E,B,1.59,-0.19,1.447,,63.26,HHH,-0.962,0.295029,0.00307177,0.408824 kka2_1:2_L92N,kka2_1:2_92,Kka2,kka2_1:2,P00552,,YES,92,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.893,-4.184,3.291,,0.007,E,B,1.59,-0.19,1.447,,63.26,HHH,-0.962,0.295029,0.00307177,0.393329 kka2_1:2_L92S,kka2_1:2_92,Kka2,kka2_1:2,P00552,,YES,92,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.893,-3.672,2.779,,0.007,E,B,1.59,-0.19,1.447,,63.26,HHH,-0.962,0.295029,0.00307177,0.465759 kka2_1:2_L93C,kka2_1:2_93,Kka2,kka2_1:2,P00552,,YES,93,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.815,-4.726,3.911,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.295029,0.00131498,0.5622 kka2_1:2_L93D,kka2_1:2_93,Kka2,kka2_1:2,P00552,,YES,93,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.815,-4.139,3.324,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.295029,0.00131498,0.447201 kka2_1:2_L93E,kka2_1:2_93,Kka2,kka2_1:2,P00552,,YES,93,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.815,-3.848,3.033,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.295029,0.00131498,0.433661 kka2_1:2_L93G,kka2_1:2_93,Kka2,kka2_1:2,P00552,,YES,93,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.815,-3.804,2.989,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.295029,0.00131498,0.513284 kka2_1:2_L93K,kka2_1:2_93,Kka2,kka2_1:2,P00552,,YES,93,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.815,-3.596,2.781,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.295029,0.00131498,0.456413 kka2_1:2_L93N,kka2_1:2_93,Kka2,kka2_1:2,P00552,,YES,93,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.815,-4.082,3.267,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.295029,0.00131498,0.418188 kka2_1:2_L93S,kka2_1:2_93,Kka2,kka2_1:2,P00552,,YES,93,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.815,-3.637,2.822,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.295029,0.00131498,0.50708 kka2_1:2_L93T,kka2_1:2_93,Kka2,kka2_1:2,P00552,,YES,93,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.815,-3.473,2.658,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.295029,0.00131498,0.536099 kka2_1:2_L93W,kka2_1:2_93,Kka2,kka2_1:2,P00552,,YES,93,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.815,-5.169,4.354,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.295029,0.00131498,0.404146 kka2_1:2_L93Y,kka2_1:2_93,Kka2,kka2_1:2,P00552,,YES,93,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.815,-4.01,3.195,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.295029,0.00131498,0.435111 kka2_1:2_M120C,kka2_1:2_120,Kka2,kka2_1:2,P00552,,YES,120,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-3.877,-4.689,0.812,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.295029,0.00265808,0.581086 kka2_1:2_M120D,kka2_1:2_120,Kka2,kka2_1:2,P00552,,YES,120,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-3.877,-4.17,0.293,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.295029,0.00265808,0.486112 kka2_1:2_M120E,kka2_1:2_120,Kka2,kka2_1:2,P00552,,YES,120,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-3.877,-3.916,0.039,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.295029,0.00265808,0.470964 kka2_1:2_M120F,kka2_1:2_120,Kka2,kka2_1:2,P00552,,YES,120,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-3.877,-3.689,-0.188,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.295029,0.00265808,0.489024 kka2_1:2_M120G,kka2_1:2_120,Kka2,kka2_1:2,P00552,,YES,120,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-3.877,-3.835,-0.042,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.295029,0.00265808,0.454363 kka2_1:2_M120H,kka2_1:2_120,Kka2,kka2_1:2,P00552,,YES,120,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-3.877,-4.957,1.08,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.295029,0.00265808,0.608875 kka2_1:2_M120N,kka2_1:2_120,Kka2,kka2_1:2,P00552,,YES,120,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-3.877,-4.174,0.297,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.295029,0.00265808,0.496119 kka2_1:2_M120P,kka2_1:2_120,Kka2,kka2_1:2,P00552,,YES,120,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-3.877,-4.131,0.254,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.295029,0.00265808,0.441694 kka2_1:2_M120Q,kka2_1:2_120,Kka2,kka2_1:2,P00552,,YES,120,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-3.877,-4.176,0.299,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.295029,0.00265808,0.508639 kka2_1:2_M120R,kka2_1:2_120,Kka2,kka2_1:2,P00552,,YES,120,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-3.877,-4.005,0.128,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.295029,0.00265808,0.497698 kka2_1:2_M120Y,kka2_1:2_120,Kka2,kka2_1:2,P00552,,YES,120,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-3.877,-3.989,0.112,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.295029,0.00265808,0.490581 kka2_1:2_M148C,kka2_1:2_148,Kka2,kka2_1:2,P00552,,YES,148,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.847,-4.865,3.018,,0.268,H,A,1.59,0.71,1.439,,64.39,BHA,-1.65467,0.295029,0.00982664,0.58397 kka2_1:2_M148E,kka2_1:2_148,Kka2,kka2_1:2,P00552,,YES,148,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.847,-3.876,2.029,,0.268,H,A,1.59,0.71,1.439,,64.39,BHA,-1.65467,0.295029,0.00982664,0.457571 kka2_1:2_M148G,kka2_1:2_148,Kka2,kka2_1:2,P00552,,YES,148,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.847,-3.731,1.884,,0.268,H,A,1.59,0.71,1.439,,64.39,BHA,-1.65467,0.295029,0.00982664,0.455355 kka2_1:2_M148H,kka2_1:2_148,Kka2,kka2_1:2,P00552,,YES,148,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.847,-4.993,3.146,,0.268,H,A,1.59,0.71,1.439,,64.39,BHA,-1.65467,0.295029,0.00982664,0.509857 kka2_1:2_M148R,kka2_1:2_148,Kka2,kka2_1:2,P00552,,YES,148,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.847,-3.206,1.359,,0.268,H,A,1.59,0.71,1.439,,64.39,BHA,-1.65467,0.295029,0.00982664,0.517898 kka2_1:2_M178K,kka2_1:2_178,Kka2,kka2_1:2,P00552,,YES,178,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-3.206,-2.451,-0.755,,0.554,.,b,0.55,0.68,3.152,,71.59,BHO,-2.154,0.295029,0.00717253,0.836941 kka2_1:2_M178N,kka2_1:2_178,Kka2,kka2_1:2,P00552,,YES,178,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-3.206,-3.899,0.693,,0.554,.,b,0.55,0.68,3.152,,71.59,BHO,-2.154,0.295029,0.00717253,0.700752 kka2_1:2_M178P,kka2_1:2_178,Kka2,kka2_1:2,P00552,,YES,178,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-3.206,-3.217,0.011,,0.554,.,b,0.55,0.68,3.152,,71.59,BHO,-2.154,0.295029,0.00717253,0.679107 kka2_1:2_M1A,kka2_1:2_1,Kka2,kka2_1:2,P00552,,YES,1,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.787,-2.808,1.021,,,,,,,1.347,,62.12,NAHH,-1.787,0.295029,0.00251939,0.830873 kka2_1:2_M1C,kka2_1:2_1,Kka2,kka2_1:2,P00552,,YES,1,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.787,-4.448,2.661,,,,,,,1.347,,62.12,NAHH,-1.787,0.295029,0.00251939,0.882897 kka2_1:2_M1D,kka2_1:2_1,Kka2,kka2_1:2,P00552,,YES,1,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.787,-3.73,1.943,,,,,,,1.347,,62.12,NAHH,-1.787,0.295029,0.00251939,0.842756 kka2_1:2_M1E,kka2_1:2_1,Kka2,kka2_1:2,P00552,,YES,1,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.787,-3.476,1.689,,,,,,,1.347,,62.12,NAHH,-1.787,0.295029,0.00251939,0.809504 kka2_1:2_M1F,kka2_1:2_1,Kka2,kka2_1:2,P00552,,YES,1,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.787,-3.498,1.711,,,,,,,1.347,,62.12,NAHH,-1.787,0.295029,0.00251939,0.820439 kka2_1:2_M1G,kka2_1:2_1,Kka2,kka2_1:2,P00552,,YES,1,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.787,-3.394,1.607,,,,,,,1.347,,62.12,NAHH,-1.787,0.295029,0.00251939,0.815781 kka2_1:2_M1H,kka2_1:2_1,Kka2,kka2_1:2,P00552,,YES,1,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.787,-4.561,2.774,,,,,,,1.347,,62.12,NAHH,-1.787,0.295029,0.00251939,0.861737 kka2_1:2_M1K,kka2_1:2_1,Kka2,kka2_1:2,P00552,,YES,1,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.787,-3.337,1.55,,,,,,,1.347,,62.12,NAHH,-1.787,0.295029,0.00251939,0.818238 kka2_1:2_M1N,kka2_1:2_1,Kka2,kka2_1:2,P00552,,YES,1,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.787,-3.778,1.991,,,,,,,1.347,,62.12,NAHH,-1.787,0.295029,0.00251939,0.858469 kka2_1:2_M1P,kka2_1:2_1,Kka2,kka2_1:2,P00552,,YES,1,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.787,-3.691,1.904,,,,,,,1.347,,62.12,NAHH,-1.787,0.295029,0.00251939,0.831311 kka2_1:2_M1Q,kka2_1:2_1,Kka2,kka2_1:2,P00552,,YES,1,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.787,-3.614,1.827,,,,,,,1.347,,62.12,NAHH,-1.787,0.295029,0.00251939,0.830038 kka2_1:2_M1S,kka2_1:2_1,Kka2,kka2_1:2,P00552,,YES,1,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.787,-3.266,1.479,,,,,,,1.347,,62.12,NAHH,-1.787,0.295029,0.00251939,0.79871 kka2_1:2_M1W,kka2_1:2_1,Kka2,kka2_1:2,P00552,,YES,1,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.787,-4.812,3.025,,,,,,,1.347,,62.12,NAHH,-1.787,0.295029,0.00251939,0.854539 kka2_1:2_M1Y,kka2_1:2_1,Kka2,kka2_1:2,P00552,,YES,1,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.787,-3.748,1.961,,,,,,,1.347,,62.12,NAHH,-1.787,0.295029,0.00251939,0.853283 kka2_1:2_N58A,kka2_1:2_58,Kka2,kka2_1:2,P00552,,YES,58,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-2.641,-1.819,-0.822,,0.131,S,A,0.43,0.72,5.729,,71.59,HPA,-1.83033,0.295029,0.00793425,0.817984 kka2_1:2_N58F,kka2_1:2_58,Kka2,kka2_1:2,P00552,,YES,58,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-2.641,-4.413,1.772,,0.131,S,A,0.43,0.72,5.729,,71.59,HPA,-1.83033,0.295029,0.00793425,0.563973 kka2_1:2_N58G,kka2_1:2_58,Kka2,kka2_1:2,P00552,,YES,58,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-2.641,-1.779,-0.862,,0.131,S,A,0.43,0.72,5.729,,71.59,HPA,-1.83033,0.295029,0.00793425,0.801298 kka2_1:2_N58H,kka2_1:2_58,Kka2,kka2_1:2,P00552,,YES,58,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-2.641,-4.779,2.138,,0.131,S,A,0.43,0.72,5.729,,71.59,HPA,-1.83033,0.295029,0.00793425,0.666497 kka2_1:2_N58I,kka2_1:2_58,Kka2,kka2_1:2,P00552,,YES,58,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-2.641,-4.075,1.434,,0.131,S,A,0.43,0.72,5.729,,71.59,HPA,-1.83033,0.295029,0.00793425,0.56044 kka2_1:2_N58L,kka2_1:2_58,Kka2,kka2_1:2,P00552,,YES,58,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-2.641,-3.653,1.012,,0.131,S,A,0.43,0.72,5.729,,71.59,HPA,-1.83033,0.295029,0.00793425,0.531138 kka2_1:2_N58M,kka2_1:2_58,Kka2,kka2_1:2,P00552,,YES,58,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-2.641,-4.871,2.23,,0.131,S,A,0.43,0.72,5.729,,71.59,HPA,-1.83033,0.295029,0.00793425,0.665603 kka2_1:2_N58P,kka2_1:2_58,Kka2,kka2_1:2,P00552,,YES,58,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-2.641,-4.016,1.375,,0.131,S,A,0.43,0.72,5.729,,71.59,HPA,-1.83033,0.295029,0.00793425,0.485045 kka2_1:2_N58Q,kka2_1:2_58,Kka2,kka2_1:2,P00552,,YES,58,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-2.641,-4.107,1.466,,0.131,S,A,0.43,0.72,5.729,,71.59,HPA,-1.83033,0.295029,0.00793425,0.578682 kka2_1:2_N58R,kka2_1:2_58,Kka2,kka2_1:2,P00552,,YES,58,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-2.641,-3.198,0.557,,0.131,S,A,0.43,0.72,5.729,,71.59,HPA,-1.83033,0.295029,0.00793425,0.643214 kka2_1:2_N58V,kka2_1:2_58,Kka2,kka2_1:2,P00552,,YES,58,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-2.641,-3.703,1.062,,0.131,S,A,0.43,0.72,5.729,,71.59,HPA,-1.83033,0.295029,0.00793425,0.539064 kka2_1:2_N58W,kka2_1:2_58,Kka2,kka2_1:2,P00552,,YES,58,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-2.641,-5.525,2.884,,0.131,S,A,0.43,0.72,5.729,,71.59,HPA,-1.83033,0.295029,0.00793425,0.681096 kka2_1:2_P109E,kka2_1:2_109,Kka2,kka2_1:2,P00552,,YES,109,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.412,-2.892,1.48,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.295029,0.0070929,0.499472 kka2_1:2_P109G,kka2_1:2_109,Kka2,kka2_1:2,P00552,,YES,109,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.412,-3.439,2.027,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.295029,0.0070929,0.518799 kka2_1:2_P109W,kka2_1:2_109,Kka2,kka2_1:2,P00552,,YES,109,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.412,-3.457,2.045,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.295029,0.0070929,0.49252 kka2_1:2_P128D,kka2_1:2_128,Kka2,kka2_1:2,P00552,,YES,128,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.922,-4.006,2.084,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.295029,0.00774689,0.41293 kka2_1:2_P128G,kka2_1:2_128,Kka2,kka2_1:2,P00552,,YES,128,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.922,-3.745,1.823,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.295029,0.00774689,0.420782 kka2_1:2_P128K,kka2_1:2_128,Kka2,kka2_1:2,P00552,,YES,128,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.922,-3.891,1.969,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.295029,0.00774689,0.417843 kka2_1:2_P128N,kka2_1:2_128,Kka2,kka2_1:2,P00552,,YES,128,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.922,-4.215,2.293,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.295029,0.00774689,0.45231 kka2_1:2_P128Y,kka2_1:2_128,Kka2,kka2_1:2,P00552,,YES,128,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.922,-3.242,1.32,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.295029,0.00774689,0.48596 kka2_1:2_P12N,kka2_1:2_12,Kka2,kka2_1:2,P00552,,YES,12,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.853,-3.936,3.083,,,.,B,0.52,1.25,0.261,,48.11,POH,-1.80767,0.295029,0.00500011,0.450385 kka2_1:2_P132C,kka2_1:2_132,Kka2,kka2_1:2,P00552,,YES,132,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.775,-5.083,4.308,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.295029,0.0018489,0.552508 kka2_1:2_P132E,kka2_1:2_132,Kka2,kka2_1:2,P00552,,YES,132,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.775,-3.466,2.691,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.295029,0.0018489,0.45921 kka2_1:2_P132F,kka2_1:2_132,Kka2,kka2_1:2,P00552,,YES,132,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.775,-4.513,3.738,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.295029,0.0018489,0.487946 kka2_1:2_P132N,kka2_1:2_132,Kka2,kka2_1:2,P00552,,YES,132,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.775,-3.857,3.082,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.295029,0.0018489,0.492266 kka2_1:2_P132Y,kka2_1:2_132,Kka2,kka2_1:2,P00552,,YES,132,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.775,-4.414,3.639,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.295029,0.0018489,0.480126 kka2_1:2_P167C,kka2_1:2_167,Kka2,kka2_1:2,P00552,,YES,167,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-2.403,-4.818,2.415,,0.18,H,A,0.52,0.75,3.6,,64.39,HOH,-2.26633,0.295029,0.00543203,0.705058 kka2_1:2_P167F,kka2_1:2_167,Kka2,kka2_1:2,P00552,,YES,167,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-2.403,-4.229,1.826,,0.18,H,A,0.52,0.75,3.6,,64.39,HOH,-2.26633,0.295029,0.00543203,0.559367 kka2_1:2_P167Y,kka2_1:2_167,Kka2,kka2_1:2,P00552,,YES,167,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-2.403,-4.35,1.947,,0.18,H,A,0.52,0.75,3.6,,64.39,HOH,-2.26633,0.295029,0.00543203,0.606293 kka2_1:2_P249C,kka2_1:2_249,Kka2,kka2_1:2,P00552,,YES,249,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.867,-5.002,3.135,,0.406,.,B,0.52,-0.01,0.76,,92.05,HOA,-1.66867,0.295029,0.011045,0.782962 kka2_1:2_P249D,kka2_1:2_249,Kka2,kka2_1:2,P00552,,YES,249,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.867,-3.169,1.302,,0.406,.,B,0.52,-0.01,0.76,,92.05,HOA,-1.66867,0.295029,0.011045,0.660994 kka2_1:2_P249G,kka2_1:2_249,Kka2,kka2_1:2,P00552,,YES,249,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.867,-3.661,1.794,,0.406,.,B,0.52,-0.01,0.76,,92.05,HOA,-1.66867,0.295029,0.011045,0.687293 kka2_1:2_P249N,kka2_1:2_249,Kka2,kka2_1:2,P00552,,YES,249,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.867,-4.142,2.275,,0.406,.,B,0.52,-0.01,0.76,,92.05,HOA,-1.66867,0.295029,0.011045,0.767793 kka2_1:2_P249Y,kka2_1:2_249,Kka2,kka2_1:2,P00552,,YES,249,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.867,-4.279,2.412,,0.406,.,B,0.52,-0.01,0.76,,92.05,HOA,-1.66867,0.295029,0.011045,0.764377 kka2_1:2_P98I,kka2_1:2_98,Kka2,kka2_1:2,P00552,,YES,98,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.526,-4.079,2.553,,0.391,S,B,0.52,-0.65,2.82,,63.26,HOO,-1.19167,0.295029,0.00622754,0.458267 kka2_1:2_P98W,kka2_1:2_98,Kka2,kka2_1:2,P00552,,YES,98,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.526,-5.629,4.103,,0.391,S,B,0.52,-0.65,2.82,,63.26,HOO,-1.19167,0.295029,0.00622754,0.493269 kka2_1:2_Q100F,kka2_1:2_100,Kka2,kka2_1:2,P00552,,YES,100,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.77,-4.378,1.608,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.295029,0.0066405,0.646986 kka2_1:2_Q155C,kka2_1:2_155,Kka2,kka2_1:2,P00552,,YES,155,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.606,-5.171,2.565,,0.525,T,A,0.64,1.49,1.592,,63.64,APA,-1.726,0.295029,0.00641853,0.872562 kka2_1:2_Q155I,kka2_1:2_155,Kka2,kka2_1:2,P00552,,YES,155,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.606,-3.926,1.32,,0.525,T,A,0.64,1.49,1.592,,63.64,APA,-1.726,0.295029,0.00641853,0.743275 kka2_1:2_Q155T,kka2_1:2_155,Kka2,kka2_1:2,P00552,,YES,155,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.606,-3.529,0.923,,0.525,T,A,0.64,1.49,1.592,,63.64,APA,-1.726,0.295029,0.00641853,0.828775 kka2_1:2_Q163S,kka2_1:2_163,Kka2,kka2_1:2,P00552,,YES,163,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.162,-3.535,1.373,,0.58,T,B,0.64,1.85,3.888,,64.02,BPO,-1.78333,0.295029,0.00719507,0.758586 kka2_1:2_Q252I,kka2_1:2_252,Kka2,kka2_1:2,P00552,,YES,252,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.63,-4.083,1.453,,0.906,H,A,0.64,0.35,5.613,,92.05,PPB,-2.20733,0.295029,0.0121001,0.843901 kka2_1:2_Q252S,kka2_1:2_252,Kka2,kka2_1:2,P00552,,YES,252,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.63,-2.755,0.125,,0.906,H,A,0.64,0.35,5.613,,92.05,PPB,-2.20733,0.295029,0.0121001,0.898236 kka2_1:2_Q26I,kka2_1:2_26,Kka2,kka2_1:2,P00552,,YES,26,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.18,-4.055,1.875,,0.448,E,B,0.4,0.44,5.022,,92.05,HPP,-2.11167,0.295029,0.00708962,0.753727 kka2_1:2_Q26S,kka2_1:2_26,Kka2,kka2_1:2,P00552,,YES,26,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.18,-3.511,1.331,,0.448,E,B,0.4,0.44,5.022,,92.05,HPP,-2.11167,0.295029,0.00708962,0.756832 kka2_1:2_Q27C,kka2_1:2_27,Kka2,kka2_1:2,P00552,,YES,27,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-1.659,-5.15,3.491,,0.608,.,A,0.64,0.71,0.521,,65.53,PPP,-1.90733,0.295029,0.00595365,0.677529 kka2_1:2_Q27G,kka2_1:2_27,Kka2,kka2_1:2,P00552,,YES,27,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-1.659,-3.564,1.905,,0.608,.,A,0.64,0.71,0.521,,65.53,PPP,-1.90733,0.295029,0.00595365,0.670351 kka2_1:2_Q27V,kka2_1:2_27,Kka2,kka2_1:2,P00552,,YES,27,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-1.659,-2.648,0.989,,0.608,.,A,0.64,0.71,0.521,,65.53,PPP,-1.90733,0.295029,0.00595365,0.672702 kka2_1:2_Q42A,kka2_1:2_42,Kka2,kka2_1:2,P00552,,YES,42,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.907,-2.221,-0.686,,1.044,T,B,0.64,-0.8,2.792,,71.59,HPO,-2.12433,0.295029,0.00679212,0.974447 kka2_1:2_Q42D,kka2_1:2_42,Kka2,kka2_1:2,P00552,,YES,42,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.907,-2.294,-0.613,,1.044,T,B,0.64,-0.8,2.792,,71.59,HPO,-2.12433,0.295029,0.00679212,0.972865 kka2_1:2_Q42F,kka2_1:2_42,Kka2,kka2_1:2,P00552,,YES,42,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.907,-4.511,1.604,,1.044,T,B,0.64,-0.8,2.792,,71.59,HPO,-2.12433,0.295029,0.00679212,0.755431 kka2_1:2_Q42V,kka2_1:2_42,Kka2,kka2_1:2,P00552,,YES,42,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.907,-3.778,0.871,,1.044,T,B,0.64,-0.8,2.792,,71.59,HPO,-2.12433,0.295029,0.00679212,0.75307 kka2_1:2_Q42W,kka2_1:2_42,Kka2,kka2_1:2,P00552,,YES,42,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.907,-5.634,2.727,,1.044,T,B,0.64,-0.8,2.792,,71.59,HPO,-2.12433,0.295029,0.00679212,0.764701 kka2_1:2_Q4G,kka2_1:2_4,Kka2,kka2_1:2,P00552,,YES,4,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.361,-1.897,-0.464,,,,,,,2.026,,71.59,APA,-1.95533,0.295029,0.00239179,1.04049 kka2_1:2_Q61I,kka2_1:2_61,Kka2,kka2_1:2,P00552,,YES,61,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.982,-3.937,0.955,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.295029,0.00612092,0.753127 kka2_1:2_Q61M,kka2_1:2_61,Kka2,kka2_1:2,P00552,,YES,61,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.982,-4.764,1.782,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.295029,0.00612092,0.773255 kka2_1:2_Q61N,kka2_1:2_61,Kka2,kka2_1:2,P00552,,YES,61,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.982,-3.133,0.151,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.295029,0.00612092,0.848484 kka2_1:2_Q61T,kka2_1:2_61,Kka2,kka2_1:2,P00552,,YES,61,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.982,-2.975,-0.007,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.295029,0.00612092,0.851762 kka2_1:2_Q61V,kka2_1:2_61,Kka2,kka2_1:2,P00552,,YES,61,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.982,-2.81,-0.172,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.295029,0.00612092,0.882333 kka2_1:2_Q61Y,kka2_1:2_61,Kka2,kka2_1:2,P00552,,YES,61,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.982,-4.455,1.473,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.295029,0.00612092,0.771068 kka2_1:2_R121A,kka2_1:2_121,Kka2,kka2_1:2,P00552,,YES,121,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.552,-2.713,1.161,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.295029,0.00523326,0.636479 kka2_1:2_R121E,kka2_1:2_121,Kka2,kka2_1:2,P00552,,YES,121,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.552,-2.795,1.243,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.295029,0.00523326,0.616769 kka2_1:2_R121F,kka2_1:2_121,Kka2,kka2_1:2,P00552,,YES,121,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.552,-4.32,2.768,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.295029,0.00523326,0.570472 kka2_1:2_R121I,kka2_1:2_121,Kka2,kka2_1:2,P00552,,YES,121,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.552,-3.978,2.426,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.295029,0.00523326,0.531623 kka2_1:2_R121K,kka2_1:2_121,Kka2,kka2_1:2,P00552,,YES,121,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.552,-2.242,0.69,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.295029,0.00523326,0.709263 kka2_1:2_R121M,kka2_1:2_121,Kka2,kka2_1:2,P00552,,YES,121,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.552,-4.593,3.041,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.295029,0.00523326,0.590629 kka2_1:2_R121N,kka2_1:2_121,Kka2,kka2_1:2,P00552,,YES,121,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.552,-3.678,2.126,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.295029,0.00523326,0.599923 kka2_1:2_R121T,kka2_1:2_121,Kka2,kka2_1:2,P00552,,YES,121,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.552,-3.59,2.038,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.295029,0.00523326,0.618852 kka2_1:2_R121V,kka2_1:2_121,Kka2,kka2_1:2,P00552,,YES,121,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.552,-3.699,2.147,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.295029,0.00523326,0.608442 kka2_1:2_R121Y,kka2_1:2_121,Kka2,kka2_1:2,P00552,,YES,121,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.552,-4.18,2.628,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.295029,0.00523326,0.571379 kka2_1:2_R122A,kka2_1:2_122,Kka2,kka2_1:2,P00552,,YES,122,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.175,-2.209,0.034,,0.487,H,A,1.2,0.26,16.436,16.436,71.59,BBH,-1.53833,0.295029,0.00736512,0.941319 kka2_1:2_R122E,kka2_1:2_122,Kka2,kka2_1:2,P00552,,YES,122,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.175,-2.696,0.521,,0.487,H,A,1.2,0.26,16.436,16.436,71.59,BBH,-1.53833,0.295029,0.00736512,0.838098 kka2_1:2_R122F,kka2_1:2_122,Kka2,kka2_1:2,P00552,,YES,122,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.175,-4.454,2.279,,0.487,H,A,1.2,0.26,16.436,16.436,71.59,BBH,-1.53833,0.295029,0.00736512,0.778186 kka2_1:2_R122I,kka2_1:2_122,Kka2,kka2_1:2,P00552,,YES,122,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.175,-4.03,1.855,,0.487,H,A,1.2,0.26,16.436,16.436,71.59,BBH,-1.53833,0.295029,0.00736512,0.728208 kka2_1:2_R122K,kka2_1:2_122,Kka2,kka2_1:2,P00552,,YES,122,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.175,-3.561,1.386,,0.487,H,A,1.2,0.26,16.436,16.436,71.59,BBH,-1.53833,0.295029,0.00736512,0.752514 kka2_1:2_R122M,kka2_1:2_122,Kka2,kka2_1:2,P00552,,YES,122,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.175,-3.353,1.178,,0.487,H,A,1.2,0.26,16.436,16.436,71.59,BBH,-1.53833,0.295029,0.00736512,0.746219 kka2_1:2_R122V,kka2_1:2_122,Kka2,kka2_1:2,P00552,,YES,122,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.175,-2.949,0.774,,0.487,H,A,1.2,0.26,16.436,16.436,71.59,BBH,-1.53833,0.295029,0.00736512,0.826657 kka2_1:2_R122Y,kka2_1:2_122,Kka2,kka2_1:2,P00552,,YES,122,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.175,-4.411,2.236,,0.487,H,A,1.2,0.26,16.436,16.436,71.59,BBH,-1.53833,0.295029,0.00736512,0.776785 kka2_1:2_R140I,kka2_1:2_140,Kka2,kka2_1:2,P00552,,YES,140,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.351,-4.1,2.749,,0.12,H,A,1.2,0.2,0.352,,53.03,BBH,-1.885,0.295029,0.00430167,0.426324 kka2_1:2_R143M,kka2_1:2_143,Kka2,kka2_1:2,P00552,,YES,143,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.525,-4.625,2.1,,0.325,H,A,0.16,1.22,14.853,14.853,65.53,ABH,-1.86833,0.295029,0.00662247,0.790282 kka2_1:2_R143W,kka2_1:2_143,Kka2,kka2_1:2,P00552,,YES,143,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.525,-5.57,3.045,,0.325,H,A,0.16,1.22,14.853,14.853,65.53,ABH,-1.86833,0.295029,0.00662247,0.770015 kka2_1:2_R145D,kka2_1:2_145,Kka2,kka2_1:2,P00552,,YES,145,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.804,-3.693,1.889,,0.346,H,A,1.2,1.23,7.961,,63.64,HBP,-1.88033,0.295029,0.00846663,0.567101 kka2_1:2_R145F,kka2_1:2_145,Kka2,kka2_1:2,P00552,,YES,145,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.804,-4.396,2.592,,0.346,H,A,1.2,1.23,7.961,,63.64,HBP,-1.88033,0.295029,0.00846663,0.589344 kka2_1:2_R145V,kka2_1:2_145,Kka2,kka2_1:2,P00552,,YES,145,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.804,-3.111,1.307,,0.346,H,A,1.2,1.23,7.961,,63.64,HBP,-1.88033,0.295029,0.00846663,0.63923 kka2_1:2_R145Y,kka2_1:2_145,Kka2,kka2_1:2,P00552,,YES,145,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.804,-4.267,2.463,,0.346,H,A,1.2,1.23,7.961,,63.64,HBP,-1.88033,0.295029,0.00846663,0.544804 kka2_1:2_R147A,kka2_1:2_147,Kka2,kka2_1:2,P00552,,YES,147,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.123,-3.267,2.144,,0.094,H,A,1.2,0.97,0.425,,64.02,PBH,-1.98267,0.295029,0.00549168,0.564841 kka2_1:2_R147D,kka2_1:2_147,Kka2,kka2_1:2,P00552,,YES,147,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.123,-3.649,2.526,,0.094,H,A,1.2,0.97,0.425,,64.02,PBH,-1.98267,0.295029,0.00549168,0.493587 kka2_1:2_R147E,kka2_1:2_147,Kka2,kka2_1:2,P00552,,YES,147,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.123,-3.304,2.181,,0.094,H,A,1.2,0.97,0.425,,64.02,PBH,-1.98267,0.295029,0.00549168,0.53943 kka2_1:2_R147M,kka2_1:2_147,Kka2,kka2_1:2,P00552,,YES,147,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.123,-4.65,3.527,,0.094,H,A,1.2,0.97,0.425,,64.02,PBH,-1.98267,0.295029,0.00549168,0.509551 kka2_1:2_R147Y,kka2_1:2_147,Kka2,kka2_1:2,P00552,,YES,147,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.123,-4.044,2.921,,0.094,H,A,1.2,0.97,0.425,,64.02,PBH,-1.98267,0.295029,0.00549168,0.479451 kka2_1:2_R18A,kka2_1:2_18,Kka2,kka2_1:2,P00552,,YES,18,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.055,-2.49,0.435,,0.474,T,A,1.2,0.54,8.405,8.405,71.59,ABH,-1.821,0.295029,0.00724065,0.849682 kka2_1:2_R18D,kka2_1:2_18,Kka2,kka2_1:2,P00552,,YES,18,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.055,-2.8,0.745,,0.474,T,A,1.2,0.54,8.405,8.405,71.59,ABH,-1.821,0.295029,0.00724065,0.81047 kka2_1:2_R18K,kka2_1:2_18,Kka2,kka2_1:2,P00552,,YES,18,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.055,-2.865,0.81,,0.474,T,A,1.2,0.54,8.405,8.405,71.59,ABH,-1.821,0.295029,0.00724065,0.881563 kka2_1:2_R202K,kka2_1:2_202,Kka2,kka2_1:2,P00552,,YES,202,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.761,-2.914,1.153,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.295029,0.00696498,0.662822 kka2_1:2_R202Y,kka2_1:2_202,Kka2,kka2_1:2,P00552,,YES,202,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.761,-4.316,2.555,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.295029,0.00696498,0.515438 kka2_1:2_R211I,kka2_1:2_211,Kka2,kka2_1:2,P00552,,YES,211,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-0.899,-4.062,3.163,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.295029,0.00204888,0.423273 kka2_1:2_R239M,kka2_1:2_239,Kka2,kka2_1:2,P00552,,YES,239,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.949,-4.723,1.774,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.295029,0.00835326,0.729233 kka2_1:2_R38A,kka2_1:2_38,Kka2,kka2_1:2,P00552,,YES,38,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.207,-3.17,1.963,,0.355,E,B,1.2,-1.13,6.872,6.872,52.27,HBH,-1.28567,0.295029,0.00372499,0.493409 kka2_1:2_R44N,kka2_1:2_44,Kka2,kka2_1:2,P00552,,YES,44,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.062,-3.108,1.046,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.295029,0.00745043,0.655889 kka2_1:2_R44Y,kka2_1:2_44,Kka2,kka2_1:2,P00552,,YES,44,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.062,-4.366,2.304,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.295029,0.00745043,0.728039 kka2_1:2_R66D,kka2_1:2_66,Kka2,kka2_1:2,P00552,,YES,66,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-0.922,-3.72,2.798,,0.103,H,A,1.2,-0.2,2.659,,46.21,HBH,-1.13567,0.295029,0.00161025,0.415578 kka2_1:2_R66F,kka2_1:2_66,Kka2,kka2_1:2,P00552,,YES,66,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-0.922,-4.355,3.433,,0.103,H,A,1.2,-0.2,2.659,,46.21,HBH,-1.13567,0.295029,0.00161025,0.444814 kka2_1:2_R66G,kka2_1:2_66,Kka2,kka2_1:2,P00552,,YES,66,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-0.922,-3.421,2.499,,0.103,H,A,1.2,-0.2,2.659,,46.21,HBH,-1.13567,0.295029,0.00161025,0.478107 kka2_1:2_R66I,kka2_1:2_66,Kka2,kka2_1:2,P00552,,YES,66,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-0.922,-4.073,3.151,,0.103,H,A,1.2,-0.2,2.659,,46.21,HBH,-1.13567,0.295029,0.00161025,0.409508 kka2_1:2_R66M,kka2_1:2_66,Kka2,kka2_1:2,P00552,,YES,66,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-0.922,-4.542,3.62,,0.103,H,A,1.2,-0.2,2.659,,46.21,HBH,-1.13567,0.295029,0.00161025,0.449939 kka2_1:2_R66N,kka2_1:2_66,Kka2,kka2_1:2,P00552,,YES,66,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-0.922,-3.51,2.588,,0.103,H,A,1.2,-0.2,2.659,,46.21,HBH,-1.13567,0.295029,0.00161025,0.422446 kka2_1:2_R66P,kka2_1:2_66,Kka2,kka2_1:2,P00552,,YES,66,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-0.922,-3.906,2.984,,0.103,H,A,1.2,-0.2,2.659,,46.21,HBH,-1.13567,0.295029,0.00161025,0.451272 kka2_1:2_R89A,kka2_1:2_89,Kka2,kka2_1:2,P00552,,YES,89,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.548,-2.806,1.258,,0.209,E,B,1.2,1.41,14.396,14.396,64.39,OBA,-1.89867,0.295029,0.00524373,0.623378 kka2_1:2_R89D,kka2_1:2_89,Kka2,kka2_1:2,P00552,,YES,89,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.548,-3.735,2.187,,0.209,E,B,1.2,1.41,14.396,14.396,64.39,OBA,-1.89867,0.295029,0.00524373,0.540781 kka2_1:2_R89E,kka2_1:2_89,Kka2,kka2_1:2,P00552,,YES,89,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.548,-2.88,1.332,,0.209,E,B,1.2,1.41,14.396,14.396,64.39,OBA,-1.89867,0.295029,0.00524373,0.608145 kka2_1:2_R89F,kka2_1:2_89,Kka2,kka2_1:2,P00552,,YES,89,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.548,-3.236,1.688,,0.209,E,B,1.2,1.41,14.396,14.396,64.39,OBA,-1.89867,0.295029,0.00524373,0.573029 kka2_1:2_R89I,kka2_1:2_89,Kka2,kka2_1:2,P00552,,YES,89,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.548,-4.125,2.577,,0.209,E,B,1.2,1.41,14.396,14.396,64.39,OBA,-1.89867,0.295029,0.00524373,0.505359 kka2_1:2_R89K,kka2_1:2_89,Kka2,kka2_1:2,P00552,,YES,89,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.548,-2.811,1.263,,0.209,E,B,1.2,1.41,14.396,14.396,64.39,OBA,-1.89867,0.295029,0.00524373,0.638949 kka2_1:2_R89M,kka2_1:2_89,Kka2,kka2_1:2,P00552,,YES,89,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.548,-4.745,3.197,,0.209,E,B,1.2,1.41,14.396,14.396,64.39,OBA,-1.89867,0.295029,0.00524373,0.550342 kka2_1:2_R89P,kka2_1:2_89,Kka2,kka2_1:2,P00552,,YES,89,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.548,-4.076,2.528,,0.209,E,B,1.2,1.41,14.396,14.396,64.39,OBA,-1.89867,0.295029,0.00524373,0.539325 kka2_1:2_R89Q,kka2_1:2_89,Kka2,kka2_1:2,P00552,,YES,89,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.548,-2.675,1.127,,0.209,E,B,1.2,1.41,14.396,14.396,64.39,OBA,-1.89867,0.295029,0.00524373,0.668068 kka2_1:2_R89T,kka2_1:2_89,Kka2,kka2_1:2,P00552,,YES,89,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.548,-2.992,1.444,,0.209,E,B,1.2,1.41,14.396,14.396,64.39,OBA,-1.89867,0.295029,0.00524373,0.600482 kka2_1:2_R89V,kka2_1:2_89,Kka2,kka2_1:2,P00552,,YES,89,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.548,-3.804,2.256,,0.209,E,B,1.2,1.41,14.396,14.396,64.39,OBA,-1.89867,0.295029,0.00524373,0.569476 kka2_1:2_R89W,kka2_1:2_89,Kka2,kka2_1:2,P00552,,YES,89,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.548,-5.305,3.757,,0.209,E,B,1.2,1.41,14.396,14.396,64.39,OBA,-1.89867,0.295029,0.00524373,0.550992 kka2_1:2_R89Y,kka2_1:2_89,Kka2,kka2_1:2,P00552,,YES,89,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.548,-2.904,1.356,,0.209,E,B,1.2,1.41,14.396,14.396,64.39,OBA,-1.89867,0.295029,0.00524373,0.624227 kka2_1:2_S104F,kka2_1:2_104,Kka2,kka2_1:2,P00552,,YES,104,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.436,-4.301,2.865,,0.536,T,A,0.27,-1.11,5.49,,63.64,HPP,-1.91433,0.295029,0.00555207,0.511066 kka2_1:2_S104H,kka2_1:2_104,Kka2,kka2_1:2,P00552,,YES,104,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.436,-3.319,1.883,,0.536,T,A,0.27,-1.11,5.49,,63.64,HPP,-1.91433,0.295029,0.00555207,0.539221 kka2_1:2_S104M,kka2_1:2_104,Kka2,kka2_1:2,P00552,,YES,104,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.436,-4.687,3.251,,0.536,T,A,0.27,-1.11,5.49,,63.64,HPP,-1.91433,0.295029,0.00555207,0.547153 kka2_1:2_S105D,kka2_1:2_105,Kka2,kka2_1:2,P00552,,YES,105,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.945,-2.638,0.693,,0.056,S,B,0.27,-1.04,3.442,,65.53,PPB,-2.17033,0.295029,0.00847233,0.577156 kka2_1:2_S105V,kka2_1:2_105,Kka2,kka2_1:2,P00552,,YES,105,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.945,-2.997,1.052,,0.056,S,B,0.27,-1.04,3.442,,65.53,PPB,-2.17033,0.295029,0.00847233,0.476795 kka2_1:2_S105W,kka2_1:2_105,Kka2,kka2_1:2,P00552,,YES,105,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.945,-5.544,3.599,,0.056,S,B,0.27,-1.04,3.442,,65.53,PPB,-2.17033,0.295029,0.00847233,0.490482 kka2_1:2_S105Y,kka2_1:2_105,Kka2,kka2_1:2,P00552,,YES,105,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.945,-4.433,2.488,,0.056,S,B,0.27,-1.04,3.442,,65.53,PPB,-2.17033,0.295029,0.00847233,0.510617 kka2_1:2_S114A,kka2_1:2_114,Kka2,kka2_1:2,P00552,,YES,114,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.527,-2.102,-0.425,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.295029,0.00705262,1.03533 kka2_1:2_S114P,kka2_1:2_114,Kka2,kka2_1:2,P00552,,YES,114,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.527,-4.051,1.524,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.295029,0.00705262,0.600639 kka2_1:2_S114V,kka2_1:2_114,Kka2,kka2_1:2,P00552,,YES,114,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.527,-2.736,0.209,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.295029,0.00705262,0.840626 kka2_1:2_S114Y,kka2_1:2_114,Kka2,kka2_1:2,P00552,,YES,114,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.527,-4.358,1.831,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.295029,0.00705262,0.74107 kka2_1:2_S11D,kka2_1:2_11,Kka2,kka2_1:2,P00552,,YES,11,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.322,-3.766,1.444,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.295029,0.00381691,0.791392 kka2_1:2_S11E,kka2_1:2_11,Kka2,kka2_1:2,P00552,,YES,11,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.322,-3.629,1.307,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.295029,0.00381691,0.815689 kka2_1:2_S11F,kka2_1:2_11,Kka2,kka2_1:2,P00552,,YES,11,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.322,-3.896,1.574,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.295029,0.00381691,0.821959 kka2_1:2_S11H,kka2_1:2_11,Kka2,kka2_1:2,P00552,,YES,11,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.322,-4.78,2.458,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.295029,0.00381691,0.812924 kka2_1:2_S11K,kka2_1:2_11,Kka2,kka2_1:2,P00552,,YES,11,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.322,-3.575,1.253,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.295029,0.00381691,0.852624 kka2_1:2_S11V,kka2_1:2_11,Kka2,kka2_1:2,P00552,,YES,11,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.322,-2.388,0.066,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.295029,0.00381691,0.940496 kka2_1:2_S204P,kka2_1:2_204,Kka2,kka2_1:2,P00552,,YES,204,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.353,-3.82,2.467,,0.144,E,A,0.27,-1.2,2.442,,65.53,HPO,-0.953333,0.295029,0.00881794,0.447567 kka2_1:2_S204Q,kka2_1:2_204,Kka2,kka2_1:2,P00552,,YES,204,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.353,-3.954,2.601,,0.144,E,A,0.27,-1.2,2.442,,65.53,HPO,-0.953333,0.295029,0.00881794,0.45279 kka2_1:2_S204Y,kka2_1:2_204,Kka2,kka2_1:2,P00552,,YES,204,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.353,-4.328,2.975,,0.144,E,A,0.27,-1.2,2.442,,65.53,HPO,-0.953333,0.295029,0.00881794,0.486491 kka2_1:2_S251A,kka2_1:2_251,Kka2,kka2_1:2,P00552,,YES,251,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.636,-2.138,-0.498,,0.712,H,A,0.27,-0.25,32.832,32.832,71.59,APP,-2.09367,0.295029,0.0138916,1.05141 kka2_1:2_S251Q,kka2_1:2_251,Kka2,kka2_1:2,P00552,,YES,251,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.636,-2.668,0.032,,0.712,H,A,0.27,-0.25,32.832,32.832,71.59,APP,-2.09367,0.295029,0.0138916,0.991294 kka2_1:2_S32D,kka2_1:2_32,Kka2,kka2_1:2,P00552,,YES,32,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-0.804,-3.272,2.468,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.295029,0.00149998,0.427788 kka2_1:2_S32W,kka2_1:2_32,Kka2,kka2_1:2,P00552,,YES,32,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-0.804,-5.351,4.547,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.295029,0.00149998,0.459175 kka2_1:2_S40F,kka2_1:2_40,Kka2,kka2_1:2,P00552,,YES,40,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.645,-4.453,1.808,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.295029,0.00693477,0.765487 kka2_1:2_S54A,kka2_1:2_54,Kka2,kka2_1:2,P00552,,YES,54,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.471,-1.705,-0.766,,0.408,S,b,0.27,1.01,0.393,,71.59,HPO,-2.259,0.295029,0.00782867,0.911918 kka2_1:2_S54D,kka2_1:2_54,Kka2,kka2_1:2,P00552,,YES,54,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.471,-2.887,0.416,,0.408,S,b,0.27,1.01,0.393,,71.59,HPO,-2.259,0.295029,0.00782867,0.708053 kka2_1:2_S54E,kka2_1:2_54,Kka2,kka2_1:2,P00552,,YES,54,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.471,-3.63,1.159,,0.408,S,b,0.27,1.01,0.393,,71.59,HPO,-2.259,0.295029,0.00782867,0.716365 kka2_1:2_S54F,kka2_1:2_54,Kka2,kka2_1:2,P00552,,YES,54,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.471,-4.27,1.799,,0.408,S,b,0.27,1.01,0.393,,71.59,HPO,-2.259,0.295029,0.00782867,0.727835 kka2_1:2_S54H,kka2_1:2_54,Kka2,kka2_1:2,P00552,,YES,54,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.471,-3.515,1.044,,0.408,S,b,0.27,1.01,0.393,,71.59,HPO,-2.259,0.295029,0.00782867,0.760521 kka2_1:2_S54L,kka2_1:2_54,Kka2,kka2_1:2,P00552,,YES,54,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.471,-2.689,0.218,,0.408,S,b,0.27,1.01,0.393,,71.59,HPO,-2.259,0.295029,0.00782867,0.76826 kka2_1:2_S54P,kka2_1:2_54,Kka2,kka2_1:2,P00552,,YES,54,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.471,-4.062,1.591,,0.408,S,b,0.27,1.01,0.393,,71.59,HPO,-2.259,0.295029,0.00782867,0.647349 kka2_1:2_S54Q,kka2_1:2_54,Kka2,kka2_1:2,P00552,,YES,54,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.471,-3.041,0.57,,0.408,S,b,0.27,1.01,0.393,,71.59,HPO,-2.259,0.295029,0.00782867,0.762581 kka2_1:2_S54V,kka2_1:2_54,Kka2,kka2_1:2,P00552,,YES,54,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.471,-2.309,-0.162,,0.408,S,b,0.27,1.01,0.393,,71.59,HPO,-2.259,0.295029,0.00782867,0.841679 kka2_1:2_S68A,kka2_1:2_68,Kka2,kka2_1:2,P00552,,YES,68,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.623,-3.303,0.68,,0.48,H,A,0.27,-0.1,2.655,,71.59,HPH,-1.40767,0.295029,0.00608265,0.785836 kka2_1:2_S68D,kka2_1:2_68,Kka2,kka2_1:2,P00552,,YES,68,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.623,-2.48,-0.143,,0.48,H,A,0.27,-0.1,2.655,,71.59,HPH,-1.40767,0.295029,0.00608265,0.811962 kka2_1:2_S68E,kka2_1:2_68,Kka2,kka2_1:2,P00552,,YES,68,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.623,-2.442,-0.181,,0.48,H,A,0.27,-0.1,2.655,,71.59,HPH,-1.40767,0.295029,0.00608265,0.834022 kka2_1:2_S68H,kka2_1:2_68,Kka2,kka2_1:2,P00552,,YES,68,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.623,-3.15,0.527,,0.48,H,A,0.27,-0.1,2.655,,71.59,HPH,-1.40767,0.295029,0.00608265,0.804314 kka2_1:2_S68K,kka2_1:2_68,Kka2,kka2_1:2,P00552,,YES,68,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.623,-2.899,0.276,,0.48,H,A,0.27,-0.1,2.655,,71.59,HPH,-1.40767,0.295029,0.00608265,0.809866 kka2_1:2_S68L,kka2_1:2_68,Kka2,kka2_1:2,P00552,,YES,68,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.623,-2.822,0.199,,0.48,H,A,0.27,-0.1,2.655,,71.59,HPH,-1.40767,0.295029,0.00608265,0.799955 kka2_1:2_S68M,kka2_1:2_68,Kka2,kka2_1:2,P00552,,YES,68,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.623,-4.761,2.138,,0.48,H,A,0.27,-0.1,2.655,,71.59,HPH,-1.40767,0.295029,0.00608265,0.843126 kka2_1:2_S68P,kka2_1:2_68,Kka2,kka2_1:2,P00552,,YES,68,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.623,-4.076,1.453,,0.48,H,A,0.27,-0.1,2.655,,71.59,HPH,-1.40767,0.295029,0.00608265,0.662158 kka2_1:2_S68Q,kka2_1:2_68,Kka2,kka2_1:2,P00552,,YES,68,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.623,-2.944,0.321,,0.48,H,A,0.27,-0.1,2.655,,71.59,HPH,-1.40767,0.295029,0.00608265,0.810732 kka2_1:2_S68V,kka2_1:2_68,Kka2,kka2_1:2,P00552,,YES,68,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.623,-3.127,0.504,,0.48,H,A,0.27,-0.1,2.655,,71.59,HPH,-1.40767,0.295029,0.00608265,0.775478 kka2_1:2_S68W,kka2_1:2_68,Kka2,kka2_1:2,P00552,,YES,68,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.623,-5.546,2.923,,0.48,H,A,0.27,-0.1,2.655,,71.59,HPH,-1.40767,0.295029,0.00608265,0.798729 kka2_1:2_S68Y,kka2_1:2_68,Kka2,kka2_1:2,P00552,,YES,68,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.623,-4.344,1.721,,0.48,H,A,0.27,-0.1,2.655,,71.59,HPH,-1.40767,0.295029,0.00608265,0.738151 kka2_1:2_T125D,kka2_1:2_125,Kka2,kka2_1:2,P00552,,YES,125,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.622,-2.647,0.025,,0.791,T,A,0.22,0.33,2.029,,92.05,BPH,-1.56933,0.295029,0.00821755,0.858069 kka2_1:2_T125E,kka2_1:2_125,Kka2,kka2_1:2,P00552,,YES,125,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.622,-2.741,0.119,,0.791,T,A,0.22,0.33,2.029,,92.05,BPH,-1.56933,0.295029,0.00821755,0.837974 kka2_1:2_T125H,kka2_1:2_125,Kka2,kka2_1:2,P00552,,YES,125,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.622,-4.735,2.113,,0.791,T,A,0.22,0.33,2.029,,92.05,BPH,-1.56933,0.295029,0.00821755,0.897403 kka2_1:2_T125Q,kka2_1:2_125,Kka2,kka2_1:2,P00552,,YES,125,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.622,-2.465,-0.157,,0.791,T,A,0.22,0.33,2.029,,92.05,BPH,-1.56933,0.295029,0.00821755,0.878698 kka2_1:2_T125R,kka2_1:2_125,Kka2,kka2_1:2,P00552,,YES,125,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.622,-2.191,-0.431,,0.791,T,A,0.22,0.33,2.029,,92.05,BPH,-1.56933,0.295029,0.00821755,0.936036 kka2_1:2_T125W,kka2_1:2_125,Kka2,kka2_1:2,P00552,,YES,125,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.622,-5.542,2.92,,0.791,T,A,0.22,0.33,2.029,,92.05,BPH,-1.56933,0.295029,0.00821755,0.837276 kka2_1:2_T130D,kka2_1:2_130,Kka2,kka2_1:2,P00552,,YES,130,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.392,-2.708,0.316,,0.561,G,A,0.22,0.77,0.5,,92.05,HPO,-1.62633,0.295029,0.00804204,0.756199 kka2_1:2_T130E,kka2_1:2_130,Kka2,kka2_1:2,P00552,,YES,130,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.392,-3.049,0.657,,0.561,G,A,0.22,0.77,0.5,,92.05,HPO,-1.62633,0.295029,0.00804204,0.75102 kka2_1:2_T130F,kka2_1:2_130,Kka2,kka2_1:2,P00552,,YES,130,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.392,-4.384,1.992,,0.561,G,A,0.22,0.77,0.5,,92.05,HPO,-1.62633,0.295029,0.00804204,0.822142 kka2_1:2_T130G,kka2_1:2_130,Kka2,kka2_1:2,P00552,,YES,130,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.392,-2.278,-0.114,,0.561,G,A,0.22,0.77,0.5,,92.05,HPO,-1.62633,0.295029,0.00804204,0.820913 kka2_1:2_T130L,kka2_1:2_130,Kka2,kka2_1:2,P00552,,YES,130,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.392,-2.848,0.456,,0.561,G,A,0.22,0.77,0.5,,92.05,HPO,-1.62633,0.295029,0.00804204,0.76272 kka2_1:2_T130Q,kka2_1:2_130,Kka2,kka2_1:2,P00552,,YES,130,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.392,-3.316,0.924,,0.561,G,A,0.22,0.77,0.5,,92.05,HPO,-1.62633,0.295029,0.00804204,0.794363 kka2_1:2_T130R,kka2_1:2_130,Kka2,kka2_1:2,P00552,,YES,130,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.392,-3.981,1.589,,0.561,G,A,0.22,0.77,0.5,,92.05,HPO,-1.62633,0.295029,0.00804204,0.778973 kka2_1:2_T130V,kka2_1:2_130,Kka2,kka2_1:2,P00552,,YES,130,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.392,-3.647,1.255,,0.561,G,A,0.22,0.77,0.5,,92.05,HPO,-1.62633,0.295029,0.00804204,0.771853 kka2_1:2_T130Y,kka2_1:2_130,Kka2,kka2_1:2,P00552,,YES,130,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.392,-4.42,2.028,,0.561,G,A,0.22,0.77,0.5,,92.05,HPO,-1.62633,0.295029,0.00804204,0.826473 kka2_1:2_T146E,kka2_1:2_146,Kka2,kka2_1:2,P00552,,YES,146,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.978,-2.468,-0.51,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.295029,0.00606474,0.907272 kka2_1:2_T146G,kka2_1:2_146,Kka2,kka2_1:2,P00552,,YES,146,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.978,-3.466,0.488,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.295029,0.00606474,0.725878 kka2_1:2_T146H,kka2_1:2_146,Kka2,kka2_1:2,P00552,,YES,146,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.978,-4.762,1.784,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.295029,0.00606474,0.742487 kka2_1:2_T146L,kka2_1:2_146,Kka2,kka2_1:2,P00552,,YES,146,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.978,-2.714,-0.264,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.295029,0.00606474,0.845861 kka2_1:2_T146V,kka2_1:2_146,Kka2,kka2_1:2,P00552,,YES,146,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.978,-2.951,-0.027,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.295029,0.00606474,0.817302 kka2_1:2_T225G,kka2_1:2_225,Kka2,kka2_1:2,P00552,,YES,225,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.393,-3.525,1.132,,0.036,H,A,0.22,-1.22,4.554,,63.64,HPB,-1.58733,0.295029,0.0113598,0.481222 kka2_1:2_T28H,kka2_1:2_28,Kka2,kka2_1:2,P00552,,YES,28,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.883,-3.548,1.665,,0.353,S,B,0.22,2.02,2.655,,63.64,PPH,-1.74467,0.295029,0.00743084,0.637107 kka2_1:2_T28L,kka2_1:2_28,Kka2,kka2_1:2,P00552,,YES,28,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.883,-2.972,1.089,,0.353,S,B,0.22,2.02,2.655,,63.64,PPH,-1.74467,0.295029,0.00743084,0.661463 kka2_1:2_T28P,kka2_1:2_28,Kka2,kka2_1:2,P00552,,YES,28,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.883,-3.202,1.319,,0.353,S,B,0.22,2.02,2.655,,63.64,PPH,-1.74467,0.295029,0.00743084,0.604422 kka2_1:2_T28V,kka2_1:2_28,Kka2,kka2_1:2,P00552,,YES,28,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.883,-2.663,0.78,,0.353,S,B,0.22,2.02,2.655,,63.64,PPH,-1.74467,0.295029,0.00743084,0.686954 kka2_1:2_T51G,kka2_1:2_51,Kka2,kka2_1:2,P00552,,YES,51,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.199,-2.948,0.749,,0.05,E,B,0.22,-0.05,13.165,13.165,63.64,BPA,-1.76767,0.295029,0.00628861,0.623657 kka2_1:2_T51L,kka2_1:2_51,Kka2,kka2_1:2,P00552,,YES,51,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.199,-2.881,0.682,,0.05,E,B,0.22,-0.05,13.165,13.165,63.64,BPA,-1.76767,0.295029,0.00628861,0.631268 kka2_1:2_T51P,kka2_1:2_51,Kka2,kka2_1:2,P00552,,YES,51,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.199,-4.078,1.879,,0.05,E,B,0.22,-0.05,13.165,13.165,63.64,BPA,-1.76767,0.295029,0.00628861,0.482289 kka2_1:2_T51R,kka2_1:2_51,Kka2,kka2_1:2,P00552,,YES,51,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.199,-3.007,0.808,,0.05,E,B,0.22,-0.05,13.165,13.165,63.64,BPA,-1.76767,0.295029,0.00628861,0.59999 kka2_1:2_T51V,kka2_1:2_51,Kka2,kka2_1:2,P00552,,YES,51,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.199,-2.337,0.138,,0.05,E,B,0.22,-0.05,13.165,13.165,63.64,BPA,-1.76767,0.295029,0.00628861,0.730327 kka2_1:2_T51W,kka2_1:2_51,Kka2,kka2_1:2,P00552,,YES,51,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.199,-5.512,3.313,,0.05,E,B,0.22,-0.05,13.165,13.165,63.64,BPA,-1.76767,0.295029,0.00628861,0.567687 kka2_1:2_T72C,kka2_1:2_72,Kka2,kka2_1:2,P00552,,YES,72,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.38,-5.141,2.761,,0.784,H,A,0.82,0.29,6.463,,65.53,HPP,-2.238,0.295029,0.00750756,0.755017 kka2_1:2_T72G,kka2_1:2_72,Kka2,kka2_1:2,P00552,,YES,72,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.38,-2.12,-0.26,,0.784,H,A,0.82,0.29,6.463,,65.53,HPP,-2.238,0.295029,0.00750756,0.866277 kka2_1:2_T72R,kka2_1:2_72,Kka2,kka2_1:2,P00552,,YES,72,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.38,-2.467,0.087,,0.784,H,A,0.82,0.29,6.463,,65.53,HPP,-2.238,0.295029,0.00750756,0.836384 kka2_1:2_T72S,kka2_1:2_72,Kka2,kka2_1:2,P00552,,YES,72,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.38,-2.339,-0.041,,0.784,H,A,0.82,0.29,6.463,,65.53,HPP,-2.238,0.295029,0.00750756,0.855667 kka2_1:2_T85D,kka2_1:2_85,Kka2,kka2_1:2,P00552,,YES,85,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.165,-2.694,0.529,,0.576,E,B,0.22,1.39,1.853,,71.59,HPA,-2.10133,0.295029,0.00634493,0.720062 kka2_1:2_T85F,kka2_1:2_85,Kka2,kka2_1:2,P00552,,YES,85,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.165,-3.388,1.223,,0.576,E,B,0.22,1.39,1.853,,71.59,HPA,-2.10133,0.295029,0.00634493,0.75288 kka2_1:2_T85G,kka2_1:2_85,Kka2,kka2_1:2,P00552,,YES,85,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.165,-3.601,1.436,,0.576,E,B,0.22,1.39,1.853,,71.59,HPA,-2.10133,0.295029,0.00634493,0.745847 kka2_1:2_T85H,kka2_1:2_85,Kka2,kka2_1:2,P00552,,YES,85,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.165,-3.24,1.075,,0.576,E,B,0.22,1.39,1.853,,71.59,HPA,-2.10133,0.295029,0.00634493,0.745965 kka2_1:2_T85K,kka2_1:2_85,Kka2,kka2_1:2,P00552,,YES,85,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.165,-3.032,0.867,,0.576,E,B,0.22,1.39,1.853,,71.59,HPA,-2.10133,0.295029,0.00634493,0.74637 kka2_1:2_T85Q,kka2_1:2_85,Kka2,kka2_1:2,P00552,,YES,85,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.165,-2.53,0.365,,0.576,E,B,0.22,1.39,1.853,,71.59,HPA,-2.10133,0.295029,0.00634493,0.755864 kka2_1:2_T85V,kka2_1:2_85,Kka2,kka2_1:2,P00552,,YES,85,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.165,-2.678,0.513,,0.576,E,B,0.22,1.39,1.853,,71.59,HPA,-2.10133,0.295029,0.00634493,0.727526 kka2_1:2_T85W,kka2_1:2_85,Kka2,kka2_1:2,P00552,,YES,85,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.165,-5.494,3.329,,0.576,E,B,0.22,1.39,1.853,,71.59,HPA,-2.10133,0.295029,0.00634493,0.766112 kka2_1:2_T85Y,kka2_1:2_85,Kka2,kka2_1:2,P00552,,YES,85,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.165,-4.263,2.098,,0.576,E,B,0.22,1.39,1.853,,71.59,HPA,-2.10133,0.295029,0.00634493,0.77107 kka2_1:2_V113F,kka2_1:2_113,Kka2,kka2_1:2,P00552,,YES,113,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.233,-3.907,2.674,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.295029,0.00650191,0.38936 kka2_1:2_V113S,kka2_1:2_113,Kka2,kka2_1:2,P00552,,YES,113,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.233,-3.696,2.463,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.295029,0.00650191,0.439132 kka2_1:2_V153T,kka2_1:2_153,Kka2,kka2_1:2,P00552,,YES,153,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.092,-3.365,2.273,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.295029,0.00501119,0.521741 kka2_1:2_V153Y,kka2_1:2_153,Kka2,kka2_1:2,P00552,,YES,153,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.092,-4.06,2.968,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.295029,0.00501119,0.45802 kka2_1:2_V16C,kka2_1:2_16,Kka2,kka2_1:2,P00552,,YES,16,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-3.087,-3.613,0.526,,0.742,T,A,0.44,0.34,1.746,,71.59,HHA,-2.211,0.295029,0.00694011,0.84318 kka2_1:2_V16K,kka2_1:2_16,Kka2,kka2_1:2,P00552,,YES,16,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-3.087,-2.781,-0.306,,0.742,T,A,0.44,0.34,1.746,,71.59,HHA,-2.211,0.295029,0.00694011,0.904525 kka2_1:2_V16N,kka2_1:2_16,Kka2,kka2_1:2,P00552,,YES,16,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-3.087,-3.138,0.051,,0.742,T,A,0.44,0.34,1.746,,71.59,HHA,-2.211,0.295029,0.00694011,0.861791 kka2_1:2_V16R,kka2_1:2_16,Kka2,kka2_1:2,P00552,,YES,16,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-3.087,-1.961,-1.126,,0.742,T,A,0.44,0.34,1.746,,71.59,HHA,-2.211,0.295029,0.00694011,0.967168 kka2_1:2_V16T,kka2_1:2_16,Kka2,kka2_1:2,P00552,,YES,16,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-3.087,-3.05,-0.037,,0.742,T,A,0.44,0.34,1.746,,71.59,HHA,-2.211,0.295029,0.00694011,0.858274 kka2_1:2_V16Y,kka2_1:2_16,Kka2,kka2_1:2,P00552,,YES,16,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-3.087,-4.365,1.278,,0.742,T,A,0.44,0.34,1.746,,71.59,HHA,-2.211,0.295029,0.00694011,0.867444 kka2_1:2_V214Q,kka2_1:2_214,Kka2,kka2_1:2,P00552,,YES,214,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.261,-4.289,3.028,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.295029,0.00692782,0.481625 kka2_1:2_V242P,kka2_1:2_242,Kka2,kka2_1:2,P00552,,YES,242,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-2.687,-4.019,1.332,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.295029,0.0102575,0.842752 kka2_1:2_V242Y,kka2_1:2_242,Kka2,kka2_1:2,P00552,,YES,242,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-2.687,-4.381,1.694,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.295029,0.0102575,0.972014 kka2_1:2_V36K,kka2_1:2_36,Kka2,kka2_1:2,P00552,,YES,36,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-0.898,-3.793,2.895,,0.292,E,B,1.48,0.21,1.064,,52.27,HHH,-1.484,0.295029,0.00245633,0.412918 kka2_1:2_V46H,kka2_1:2_46,Kka2,kka2_1:2,P00552,,YES,46,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-2.62,-3.614,0.994,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.295029,0.00631301,0.645577 kka2_1:2_V46Y,kka2_1:2_46,Kka2,kka2_1:2,P00552,,YES,46,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-2.62,-4.392,1.772,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.295029,0.00631301,0.626772 kka2_1:2_V75Q,kka2_1:2_75,Kka2,kka2_1:2,P00552,,YES,75,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-2.06,-2.734,0.674,,0.042,.,B,0.44,-0.2,2.815,,71.59,OHO,-1.563,0.295029,0.00693733,0.676714 kka2_1:2_V83H,kka2_1:2_83,Kka2,kka2_1:2,P00552,,YES,83,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-2.567,-2.84,0.273,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.295029,0.00650486,0.828813 kka2_1:2_V83I,kka2_1:2_83,Kka2,kka2_1:2,P00552,,YES,83,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-2.567,-3.777,1.21,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.295029,0.00650486,0.705317 kka2_1:2_V83N,kka2_1:2_83,Kka2,kka2_1:2,P00552,,YES,83,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-2.567,-3.217,0.65,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.295029,0.00650486,0.774893 kka2_1:2_V83R,kka2_1:2_83,Kka2,kka2_1:2,P00552,,YES,83,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-2.567,-2.854,0.287,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.295029,0.00650486,0.827141 kka2_1:2_V83S,kka2_1:2_83,Kka2,kka2_1:2,P00552,,YES,83,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-2.567,-2.85,0.283,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.295029,0.00650486,0.802617 kka2_1:2_V83T,kka2_1:2_83,Kka2,kka2_1:2,P00552,,YES,83,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-2.567,-2.28,-0.287,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.295029,0.00650486,0.893546 kka2_1:2_V83W,kka2_1:2_83,Kka2,kka2_1:2,P00552,,YES,83,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-2.567,-5.342,2.775,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.295029,0.00650486,0.773241 kka2_1:2_V84C,kka2_1:2_84,Kka2,kka2_1:2,P00552,,YES,84,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-2.279,-5.009,2.73,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.295029,0.00724019,0.846613 kka2_1:2_V84D,kka2_1:2_84,Kka2,kka2_1:2,P00552,,YES,84,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-2.279,-2.613,0.334,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.295029,0.00724019,0.739967 kka2_1:2_V84E,kka2_1:2_84,Kka2,kka2_1:2,P00552,,YES,84,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-2.279,-2.088,-0.191,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.295029,0.00724019,0.846607 kka2_1:2_V84N,kka2_1:2_84,Kka2,kka2_1:2,P00552,,YES,84,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-2.279,-3.883,1.604,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.295029,0.00724019,0.713334 kka2_1:2_V84Q,kka2_1:2_84,Kka2,kka2_1:2,P00552,,YES,84,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-2.279,-3.218,0.939,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.295029,0.00724019,0.750665 kka2_1:2_V84R,kka2_1:2_84,Kka2,kka2_1:2,P00552,,YES,84,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-2.279,-3.996,1.717,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.295029,0.00724019,0.707715 kka2_1:2_V84T,kka2_1:2_84,Kka2,kka2_1:2,P00552,,YES,84,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-2.279,-2.154,-0.125,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.295029,0.00724019,0.866453 kka2_1:2_V84W,kka2_1:2_84,Kka2,kka2_1:2,P00552,,YES,84,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-2.279,-5.522,3.243,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.295029,0.00724019,0.747401 kka2_1:2_V84Y,kka2_1:2_84,Kka2,kka2_1:2,P00552,,YES,84,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-2.279,-4.308,2.029,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.295029,0.00724019,0.71605 kka2_1:2_V97S,kka2_1:2_97,Kka2,kka2_1:2,P00552,,YES,97,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.453,-3.709,2.256,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.295029,0.00737869,0.484908 kka2_1:2_V97T,kka2_1:2_97,Kka2,kka2_1:2,P00552,,YES,97,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.453,-3.491,2.038,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.295029,0.00737869,0.497467 kka2_1:2_W15A,kka2_1:2_15,Kka2,kka2_1:2,P00552,,YES,15,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-1.392,-3.416,2.024,,0.01,G,A,0.47,0.15,2.586,,52.27,HHH,-2.10533,0.295029,0.00585505,0.492806 kka2_1:2_W15E,kka2_1:2_15,Kka2,kka2_1:2,P00552,,YES,15,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-1.392,-4.005,2.613,,0.01,G,A,0.47,0.15,2.586,,52.27,HHH,-2.10533,0.295029,0.00585505,0.422119 kka2_1:2_W15H,kka2_1:2_15,Kka2,kka2_1:2,P00552,,YES,15,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-1.392,-4.848,3.456,,0.01,G,A,0.47,0.15,2.586,,52.27,HHH,-2.10533,0.295029,0.00585505,0.46505 kka2_1:2_W15I,kka2_1:2_15,Kka2,kka2_1:2,P00552,,YES,15,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-1.392,-2.748,1.356,,0.01,G,A,0.47,0.15,2.586,,52.27,HHH,-2.10533,0.295029,0.00585505,0.510221 kka2_1:2_W236V,kka2_1:2_236,Kka2,kka2_1:2,P00552,,YES,236,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-1.363,-3.56,2.197,,0.303,H,A,1.51,-0.76,5.58,,48.48,AHH,-1.81267,0.295029,0.0088796,0.482499 kka2_1:2_W24K,kka2_1:2_24,Kka2,kka2_1:2,P00552,,YES,24,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-1.779,-4.012,2.233,,0.477,E,B,1.51,-0.21,2.666,,56.06,AHH,-2.24467,0.295029,0.00631564,0.434711 kka2_1:2_W69A,kka2_1:2_69,Kka2,kka2_1:2,P00552,,YES,69,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-0.859,-3.554,2.695,,0.164,H,A,0.47,0.15,5.074,,38.64,PHH,-1.49967,0.295029,0.0012874,0.434849 kka2_1:2_W69E,kka2_1:2_69,Kka2,kka2_1:2,P00552,,YES,69,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-0.859,-3.916,3.057,,0.164,H,A,0.47,0.15,5.074,,38.64,PHH,-1.49967,0.295029,0.0012874,0.398961 kka2_1:2_W69I,kka2_1:2_69,Kka2,kka2_1:2,P00552,,YES,69,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-0.859,-4.006,3.147,,0.164,H,A,0.47,0.15,5.074,,38.64,PHH,-1.49967,0.295029,0.0012874,0.381573 kka2_1:2_W69K,kka2_1:2_69,Kka2,kka2_1:2,P00552,,YES,69,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-0.859,-3.933,3.074,,0.164,H,A,0.47,0.15,5.074,,38.64,PHH,-1.49967,0.295029,0.0012874,0.397653 kka2_1:2_W69S,kka2_1:2_69,Kka2,kka2_1:2,P00552,,YES,69,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-0.859,-3.862,3.003,,0.164,H,A,0.47,0.15,5.074,,38.64,PHH,-1.49967,0.295029,0.0012874,0.45155 kka2_1:2_W91K,kka2_1:2_91,Kka2,kka2_1:2,P00552,,YES,91,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-1.178,-3.72,2.542,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.295029,0.00358653,0.482402 kka2_1:2_W91T,kka2_1:2_91,Kka2,kka2_1:2,P00552,,YES,91,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-1.178,-3.718,2.54,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.295029,0.00358653,0.534507 kka2_1:2_Y218A,kka2_1:2_218,Kka2,kka2_1:2,P00552,,YES,218,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-1.438,-2.767,1.329,,0.122,H,A,0.21,-0.69,1.022,,56.06,BHP,-1.17533,0.295029,0.0126098,0.517785 kka2_1:2_Y218Q,kka2_1:2_218,Kka2,kka2_1:2,P00552,,YES,218,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-1.438,-4.079,2.641,,0.122,H,A,0.21,-0.69,1.022,,56.06,BHP,-1.17533,0.295029,0.0126098,0.480391 kka2_1:2_Y22A,kka2_1:2_22,Kka2,kka2_1:2,P00552,,YES,22,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-1.583,-1.97,0.387,,0.122,.,B,0.21,-0.8,1.838,,65.53,OHA,-1.80333,0.295029,0.00598977,0.628086 kka2_1:2_Y22T,kka2_1:2_22,Kka2,kka2_1:2,P00552,,YES,22,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-1.583,-2.95,1.367,,0.122,.,B,0.21,-0.8,1.838,,65.53,OHA,-1.80333,0.295029,0.00598977,0.550501 kka2_1:2_Y22V,kka2_1:2_22,Kka2,kka2_1:2,P00552,,YES,22,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-1.583,-3.487,1.904,,0.122,.,B,0.21,-0.8,1.838,,65.53,OHA,-1.80333,0.295029,0.00598977,0.516043 kka2_1:4_A108K,kka2_1:4_108,Kka2,kka2_1:4,P00552,,YES,108,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.061,-3.668,1.607,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.168804,0.00751209,0.599195 kka2_1:4_A110C,kka2_1:4_110,Kka2,kka2_1:4,P00552,,YES,110,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.064,-5.167,3.103,,0.175,H,A,0.46,-1.19,23.237,23.237,71.59,OHA,-1.91867,0.168804,0.00759851,0.77008 kka2_1:4_A117I,kka2_1:4_117,Kka2,kka2_1:4,P00552,,YES,117,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.828,-3.432,2.604,,,H,A,0.46,-0.78,0.224,,45.83,HHA,-1.79333,0.168804,0.00282984,0.39758 kka2_1:4_A119F,kka2_1:4_119,Kka2,kka2_1:4,P00552,,YES,119,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.073,-4.171,3.098,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.168804,0.00441074,0.436957 kka2_1:4_A119H,kka2_1:4_119,Kka2,kka2_1:4,P00552,,YES,119,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.073,-4.774,3.701,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.168804,0.00441074,0.472881 kka2_1:4_A119I,kka2_1:4_119,Kka2,kka2_1:4,P00552,,YES,119,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.073,-3.591,2.518,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.168804,0.00441074,0.42637 kka2_1:4_A119N,kka2_1:4_119,Kka2,kka2_1:4,P00552,,YES,119,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.073,-3.831,2.758,,0.019,H,A,0.46,-0.57,2.542,,71.59,AHH,-2.34,0.168804,0.00441074,0.426048 kka2_1:4_A129C,kka2_1:4_129,Kka2,kka2_1:4,P00552,,YES,129,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.656,-5.053,3.397,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.168804,0.00726862,0.80658 kka2_1:4_A129F,kka2_1:4_129,Kka2,kka2_1:4,P00552,,YES,129,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.656,-4.391,2.735,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.168804,0.00726862,0.796528 kka2_1:4_A129H,kka2_1:4_129,Kka2,kka2_1:4,P00552,,YES,129,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.656,-3.201,1.545,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.168804,0.00726862,0.762131 kka2_1:4_A129K,kka2_1:4_129,Kka2,kka2_1:4,P00552,,YES,129,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.656,-3.023,1.367,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.168804,0.00726862,0.765339 kka2_1:4_A129N,kka2_1:4_129,Kka2,kka2_1:4,P00552,,YES,129,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.656,-2.9,1.244,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.168804,0.00726862,0.766948 kka2_1:4_A129R,kka2_1:4_129,Kka2,kka2_1:4,P00552,,YES,129,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.656,-2.972,1.316,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.168804,0.00726862,0.771802 kka2_1:4_A129Y,kka2_1:4_129,Kka2,kka2_1:4,P00552,,YES,129,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.656,-4.374,2.718,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.168804,0.00726862,0.795545 kka2_1:4_A13H,kka2_1:4_13,Kka2,kka2_1:4,P00552,,YES,13,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.248,-3.721,1.473,,0.689,G,A,0.46,0.99,,,92.05,OHH,-1.646,0.168804,0.00784241,0.887622 kka2_1:4_A13K,kka2_1:4_13,Kka2,kka2_1:4,P00552,,YES,13,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.248,-3.012,0.764,,0.689,G,A,0.46,0.99,,,92.05,OHH,-1.646,0.168804,0.00784241,0.889009 kka2_1:4_A13L,kka2_1:4_13,Kka2,kka2_1:4,P00552,,YES,13,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.248,-2.945,0.697,,0.689,G,A,0.46,0.99,,,92.05,OHH,-1.646,0.168804,0.00784241,0.880535 kka2_1:4_A13N,kka2_1:4_13,Kka2,kka2_1:4,P00552,,YES,13,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.248,-3.116,0.868,,0.689,G,A,0.46,0.99,,,92.05,OHH,-1.646,0.168804,0.00784241,0.917178 kka2_1:4_A13Y,kka2_1:4_13,Kka2,kka2_1:4,P00552,,YES,13,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.248,-4.443,2.195,,0.689,G,A,0.46,0.99,,,92.05,OHH,-1.646,0.168804,0.00784241,0.935934 kka2_1:4_A144I,kka2_1:4_144,Kka2,kka2_1:4,P00552,,YES,144,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.859,-3.396,2.537,,,H,A,0.46,0.21,6.844,,52.65,BHB,-1.72933,0.168804,0.00231095,0.396053 kka2_1:4_A144P,kka2_1:4_144,Kka2,kka2_1:4,P00552,,YES,144,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.859,-3.765,2.906,,,H,A,0.46,0.21,6.844,,52.65,BHB,-1.72933,0.168804,0.00231095,0.448647 kka2_1:4_A14C,kka2_1:4_14,Kka2,kka2_1:4,P00552,,YES,14,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.837,-5.018,3.181,,0.728,G,A,0.46,0.7,0.36,,71.59,HHH,-1.82567,0.168804,0.00706614,0.792859 kka2_1:4_A14F,kka2_1:4_14,Kka2,kka2_1:4,P00552,,YES,14,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.837,-4.392,2.555,,0.728,G,A,0.46,0.7,0.36,,71.59,HHH,-1.82567,0.168804,0.00706614,0.772336 kka2_1:4_A14N,kka2_1:4_14,Kka2,kka2_1:4,P00552,,YES,14,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.837,-3.807,1.97,,0.728,G,A,0.46,0.7,0.36,,71.59,HHH,-1.82567,0.168804,0.00706614,0.774269 kka2_1:4_A14R,kka2_1:4_14,Kka2,kka2_1:4,P00552,,YES,14,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.837,-2.714,0.877,,0.728,G,A,0.46,0.7,0.36,,71.59,HHH,-1.82567,0.168804,0.00706614,0.79626 kka2_1:4_A150C,kka2_1:4_150,Kka2,kka2_1:4,P00552,,YES,150,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.949,-4.673,3.724,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.168804,0.0045009,0.713745 kka2_1:4_A150Y,kka2_1:4_150,Kka2,kka2_1:4,P00552,,YES,150,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.949,-4.269,3.32,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.168804,0.0045009,0.622011 kka2_1:4_A168I,kka2_1:4_168,Kka2,kka2_1:4,P00552,,YES,168,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.989,-4.068,2.079,,0.67,H,A,0.46,0.15,,,64.39,OHA,-2.12933,0.168804,0.00806773,0.734515 kka2_1:4_A224C,kka2_1:4_224,Kka2,kka2_1:4,P00552,,YES,224,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.977,-4.591,3.614,,,H,A,0.46,-1.26,0.93,,63.64,HHP,-1.41033,0.168804,0.00352047,0.519419 kka2_1:4_A224I,kka2_1:4_224,Kka2,kka2_1:4,P00552,,YES,224,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.977,-3.567,2.59,,,H,A,0.46,-1.26,0.93,,63.64,HHP,-1.41033,0.168804,0.00352047,0.39761 kka2_1:4_A237F,kka2_1:4_237,Kka2,kka2_1:4,P00552,,YES,237,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.12,-4.013,1.893,,0.068,H,A,0.46,-0.71,2.444,,92.05,HHA,-2.10433,0.168804,0.012257,0.451307 kka2_1:4_A237H,kka2_1:4_237,Kka2,kka2_1:4,P00552,,YES,237,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.12,-4.997,2.877,,0.068,H,A,0.46,-0.71,2.444,,92.05,HHA,-2.10433,0.168804,0.012257,0.537533 kka2_1:4_A237Y,kka2_1:4_237,Kka2,kka2_1:4,P00552,,YES,237,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.12,-4.178,2.058,,0.068,H,A,0.46,-0.71,2.444,,92.05,HHA,-2.10433,0.168804,0.012257,0.467537 kka2_1:4_A247F,kka2_1:4_247,Kka2,kka2_1:4,P00552,,YES,247,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.459,-3.316,0.857,,1.01,S,A,0.46,0.65,,,92.05,HHH,-2.197,0.168804,0.0102428,0.91853 kka2_1:4_A247H,kka2_1:4_247,Kka2,kka2_1:4,P00552,,YES,247,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.459,-3.473,1.014,,1.01,S,A,0.46,0.65,,,92.05,HHH,-2.197,0.168804,0.0102428,0.928339 kka2_1:4_A248C,kka2_1:4_248,Kka2,kka2_1:4,P00552,,YES,248,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.124,-5.173,3.049,,0.825,S,b,0.46,0.46,,,92.05,HHO,-2.15,0.168804,0.0125484,0.849687 kka2_1:4_A248F,kka2_1:4_248,Kka2,kka2_1:4,P00552,,YES,248,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.124,-4.425,2.301,,0.825,S,b,0.46,0.46,,,92.05,HHO,-2.15,0.168804,0.0125484,0.865827 kka2_1:4_A248H,kka2_1:4_248,Kka2,kka2_1:4,P00552,,YES,248,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.124,-3.589,1.465,,0.825,S,b,0.46,0.46,,,92.05,HHO,-2.15,0.168804,0.0125484,0.868344 kka2_1:4_A248I,kka2_1:4_248,Kka2,kka2_1:4,P00552,,YES,248,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.124,-3.04,0.916,,0.825,S,b,0.46,0.46,,,92.05,HHO,-2.15,0.168804,0.0125484,0.836627 kka2_1:4_A248N,kka2_1:4_248,Kka2,kka2_1:4,P00552,,YES,248,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.124,-3.883,1.759,,0.825,S,b,0.46,0.46,,,92.05,HHO,-2.15,0.168804,0.0125484,0.831335 kka2_1:4_A248Q,kka2_1:4_248,Kka2,kka2_1:4,P00552,,YES,248,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.124,-2.728,0.604,,0.825,S,b,0.46,0.46,,,92.05,HHO,-2.15,0.168804,0.0125484,0.863399 kka2_1:4_A248Y,kka2_1:4_248,Kka2,kka2_1:4,P00552,,YES,248,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.124,-4.406,2.282,,0.825,S,b,0.46,0.46,,,92.05,HHO,-2.15,0.168804,0.0125484,0.879879 kka2_1:4_A25I,kka2_1:4_25,Kka2,kka2_1:4,P00552,,YES,25,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.496,-3.984,1.488,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.168804,0.00595636,0.606972 kka2_1:4_A25K,kka2_1:4_25,Kka2,kka2_1:4,P00552,,YES,25,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.496,-2.905,0.409,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.168804,0.00595636,0.766922 kka2_1:4_A25Y,kka2_1:4_25,Kka2,kka2_1:4,P00552,,YES,25,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.496,-4.311,1.815,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.168804,0.00595636,0.647616 kka2_1:4_A34H,kka2_1:4_34,Kka2,kka2_1:4,P00552,,YES,34,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.928,-4.681,3.753,,0.417,.,B,0.46,2.29,0.262,,52.27,AHH,-1.747,0.168804,0.00343484,0.428778 kka2_1:4_A34I,kka2_1:4_34,Kka2,kka2_1:4,P00552,,YES,34,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.928,-3.671,2.743,,0.417,.,B,0.46,2.29,0.262,,52.27,AHH,-1.747,0.168804,0.00343484,0.417429 kka2_1:4_A34K,kka2_1:4_34,Kka2,kka2_1:4,P00552,,YES,34,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.928,-3.458,2.53,,0.417,.,B,0.46,2.29,0.262,,52.27,AHH,-1.747,0.168804,0.00343484,0.454857 kka2_1:4_A34N,kka2_1:4_34,Kka2,kka2_1:4,P00552,,YES,34,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.928,-3.748,2.82,,0.417,.,B,0.46,2.29,0.262,,52.27,AHH,-1.747,0.168804,0.00343484,0.420569 kka2_1:4_A35F,kka2_1:4_35,Kka2,kka2_1:4,P00552,,YES,35,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.127,-4.402,2.275,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.168804,0.00630016,0.653172 kka2_1:4_A35H,kka2_1:4_35,Kka2,kka2_1:4,P00552,,YES,35,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.127,-3.517,1.39,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.168804,0.00630016,0.674501 kka2_1:4_A35I,kka2_1:4_35,Kka2,kka2_1:4,P00552,,YES,35,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.127,-4.036,1.909,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.168804,0.00630016,0.653329 kka2_1:4_A35N,kka2_1:4_35,Kka2,kka2_1:4,P00552,,YES,35,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.127,-2.713,0.586,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.168804,0.00630016,0.762294 kka2_1:4_A35R,kka2_1:4_35,Kka2,kka2_1:4,P00552,,YES,35,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.127,-3.236,1.109,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.168804,0.00630016,0.695955 kka2_1:4_A35Y,kka2_1:4_35,Kka2,kka2_1:4,P00552,,YES,35,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.127,-4.416,2.289,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.168804,0.00630016,0.66253 kka2_1:4_A41K,kka2_1:4_41,Kka2,kka2_1:4,P00552,,YES,41,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.879,-3.682,1.803,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.168804,0.00543332,0.577081 kka2_1:4_A56K,kka2_1:4_56,Kka2,kka2_1:4,P00552,,YES,56,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.083,-3.671,1.588,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.168804,0.00717715,0.814696 kka2_1:4_A56Y,kka2_1:4_56,Kka2,kka2_1:4,P00552,,YES,56,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.083,-4.486,2.403,,0.796,T,A,1.04,1.39,3.311,,71.59,OHH,-1.86867,0.168804,0.00717715,0.875056 kka2_1:4_A64F,kka2_1:4_64,Kka2,kka2_1:4,P00552,,YES,64,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.496,-4.09,2.594,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.168804,0.00705578,0.485635 kka2_1:4_A64I,kka2_1:4_64,Kka2,kka2_1:4,P00552,,YES,64,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.496,-1.939,0.443,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.168804,0.00705578,0.637201 kka2_1:4_A64Q,kka2_1:4_64,Kka2,kka2_1:4,P00552,,YES,64,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.496,-4.195,2.699,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.168804,0.00705578,0.500513 kka2_1:4_A64W,kka2_1:4_64,Kka2,kka2_1:4,P00552,,YES,64,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.496,-5.479,3.983,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.168804,0.00705578,0.471532 kka2_1:4_A65D,kka2_1:4_65,Kka2,kka2_1:4,P00552,,YES,65,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.744,-2.659,0.915,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.168804,0.00709258,0.657591 kka2_1:4_A65H,kka2_1:4_65,Kka2,kka2_1:4,P00552,,YES,65,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.744,-3.525,1.781,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.168804,0.00709258,0.64958 kka2_1:4_A65I,kka2_1:4_65,Kka2,kka2_1:4,P00552,,YES,65,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.744,-3.823,2.079,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.168804,0.00709258,0.61965 kka2_1:4_A65N,kka2_1:4_65,Kka2,kka2_1:4,P00552,,YES,65,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.744,-3.167,1.423,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.168804,0.00709258,0.647896 kka2_1:4_A65R,kka2_1:4_65,Kka2,kka2_1:4,P00552,,YES,65,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.744,-3.924,2.18,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.168804,0.00709258,0.686498 kka2_1:4_A71F,kka2_1:4_71,Kka2,kka2_1:4,P00552,,YES,71,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.824,-4.432,2.608,,0.553,H,A,0.46,0.08,5.76,,64.39,HHP,-1.74033,0.168804,0.00727707,0.685242 kka2_1:4_A71K,kka2_1:4_71,Kka2,kka2_1:4,P00552,,YES,71,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.824,-2.499,0.675,,0.553,H,A,0.46,0.08,5.76,,64.39,HHP,-1.74033,0.168804,0.00727707,0.74266 kka2_1:4_A71P,kka2_1:4_71,Kka2,kka2_1:4,P00552,,YES,71,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.824,-4.026,2.202,,0.553,H,A,0.46,0.08,5.76,,64.39,HHP,-1.74033,0.168804,0.00727707,0.584086 kka2_1:4_A79P,kka2_1:4_79,Kka2,kka2_1:4,P00552,,YES,79,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.368,-3.3,0.932,,0.563,.,B,0.46,-0.43,2.291,,71.59,HHH,-1.752,0.168804,0.00664821,0.74747 kka2_1:4_A87I,kka2_1:4_87,Kka2,kka2_1:4,P00552,,YES,87,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.917,-4.113,2.196,,1.039,S,L,0.46,1.57,22.675,22.675,65.53,AHO,-1.822,0.168804,0.00791281,0.740017 kka2_1:4_A87K,kka2_1:4_87,Kka2,kka2_1:4,P00552,,YES,87,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.917,-3.626,1.709,,1.039,S,L,0.46,1.57,22.675,22.675,65.53,AHO,-1.822,0.168804,0.00791281,0.806136 kka2_1:4_A87M,kka2_1:4_87,Kka2,kka2_1:4,P00552,,YES,87,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.917,-4.877,2.96,,1.039,S,L,0.46,1.57,22.675,22.675,65.53,AHO,-1.822,0.168804,0.00791281,0.808809 kka2_1:4_A87N,kka2_1:4_87,Kka2,kka2_1:4,P00552,,YES,87,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.917,-2.703,0.786,,1.039,S,L,0.46,1.57,22.675,22.675,65.53,AHO,-1.822,0.168804,0.00791281,0.83531 kka2_1:4_A87R,kka2_1:4_87,Kka2,kka2_1:4,P00552,,YES,87,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.917,-3.21,1.293,,1.039,S,L,0.46,1.57,22.675,22.675,65.53,AHO,-1.822,0.168804,0.00791281,0.83222 kka2_1:4_A87W,kka2_1:4_87,Kka2,kka2_1:4,P00552,,YES,87,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.917,-5.563,3.646,,1.039,S,L,0.46,1.57,22.675,22.675,65.53,AHO,-1.822,0.168804,0.00791281,0.754746 kka2_1:4_A87Y,kka2_1:4_87,Kka2,kka2_1:4,P00552,,YES,87,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.917,-4.401,2.484,,1.039,S,L,0.46,1.57,22.675,22.675,65.53,AHO,-1.822,0.168804,0.00791281,0.798627 kka2_1:4_A9H,kka2_1:4_9,Kka2,kka2_1:4,P00552,,YES,9,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.079,-4.629,2.55,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.168804,0.00273264,0.915051 kka2_1:4_A9K,kka2_1:4_9,Kka2,kka2_1:4,P00552,,YES,9,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.079,-3.506,1.427,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.168804,0.00273264,0.921906 kka2_1:4_C131A,kka2_1:4_131,Kka2,kka2_1:4,P00552,,YES,131,C,A,CA,Special,Hydrophobic,5.07,6,0.93,195,121,89,-32,108.5,88.6,-19.9,-0.831,-2.881,2.05,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.168804,0.00170814,0.484594 kka2_1:4_C131D,kka2_1:4_131,Kka2,kka2_1:4,P00552,,YES,131,C,D,CD,Special,negativeCharge,5.07,5.0516,-0.0184,154,121,133,12,108.5,111.1,2.6,-0.831,-3.947,3.116,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.168804,0.00170814,0.449708 kka2_1:4_C131E,kka2_1:4_131,Kka2,kka2_1:4,P00552,,YES,131,C,E,CE,Special,negativeCharge,5.07,3.22,-1.85,170,121,147,26,108.5,138.4,29.9,-0.831,-4.143,3.312,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.168804,0.00170814,0.440501 kka2_1:4_C131H,kka2_1:4_131,Kka2,kka2_1:4,P00552,,YES,131,C,H,CH,Special,PositiveCharge,5.07,7.59,2.52,174,121,155,34,108.5,153.2,44.7,-0.831,-4.933,4.102,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.168804,0.00170814,0.428069 kka2_1:4_C131I,kka2_1:4_131,Kka2,kka2_1:4,P00552,,YES,131,C,I,CI,Special,Hydrophobic,5.07,6.02,0.95,198,121,131,10,108.5,166.7,58.2,-0.831,-3.589,2.758,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.168804,0.00170814,0.451677 kka2_1:4_C131K,kka2_1:4_131,Kka2,kka2_1:4,P00552,,YES,131,C,K,CK,Special,PositiveCharge,5.07,9.74,4.67,202,121,146,25,108.5,168.6,60.1,-0.831,-3.935,3.104,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.168804,0.00170814,0.458796 kka2_1:4_C131M,kka2_1:4_131,Kka2,kka2_1:4,P00552,,YES,131,C,M,CM,Special,Hydrophobic,5.07,5.74,0.67,196,121,149,28,108.5,162.9,54.4,-0.831,-4.508,3.677,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.168804,0.00170814,0.446769 kka2_1:4_C131P,kka2_1:4_131,Kka2,kka2_1:4,P00552,,YES,131,C,P,CP,Special,Special,5.07,6.3,1.23,169,121,115,-6,108.5,112.7,4.2,-0.831,-4.133,3.302,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.168804,0.00170814,0.460115 kka2_1:4_C131Q,kka2_1:4_131,Kka2,kka2_1:4,P00552,,YES,131,C,Q,CQ,Special,Polar,5.07,6.24429,1.17429,154,121,146,25,108.5,143.8,35.3,-0.831,-4.378,3.547,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.168804,0.00170814,0.43785 kka2_1:4_C31A,kka2_1:4_31,Kka2,kka2_1:4,P00552,,YES,31,C,A,CA,Special,Hydrophobic,5.07,6,0.93,195,121,89,-32,108.5,88.6,-19.9,-2.246,-2.378,0.132,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.168804,0.00681582,0.829941 kka2_1:4_C31D,kka2_1:4_31,Kka2,kka2_1:4,P00552,,YES,31,C,D,CD,Special,negativeCharge,5.07,5.0516,-0.0184,154,121,133,12,108.5,111.1,2.6,-2.246,-3.622,1.376,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.168804,0.00681582,0.676851 kka2_1:4_C31H,kka2_1:4_31,Kka2,kka2_1:4,P00552,,YES,31,C,H,CH,Special,PositiveCharge,5.07,7.59,2.52,174,121,155,34,108.5,153.2,44.7,-2.246,-3.333,1.087,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.168804,0.00681582,0.767785 kka2_1:4_C31M,kka2_1:4_31,Kka2,kka2_1:4,P00552,,YES,31,C,M,CM,Special,Hydrophobic,5.07,5.74,0.67,196,121,149,28,108.5,162.9,54.4,-2.246,-4.677,2.431,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.168804,0.00681582,0.666908 kka2_1:4_C31P,kka2_1:4_31,Kka2,kka2_1:4,P00552,,YES,31,C,P,CP,Special,Special,5.07,6.3,1.23,169,121,115,-6,108.5,112.7,4.2,-2.246,-4.029,1.783,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.168804,0.00681582,0.577649 kka2_1:4_C31Q,kka2_1:4_31,Kka2,kka2_1:4,P00552,,YES,31,C,Q,CQ,Special,Polar,5.07,6.24429,1.17429,154,121,146,25,108.5,143.8,35.3,-2.246,-2.477,0.231,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.168804,0.00681582,0.807346 kka2_1:4_D101L,kka2_1:4_101,Kka2,kka2_1:4,P00552,,YES,101,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.028,-3.645,2.617,,0.213,E,B,0.75,-1.24,8.707,,63.64,PAH,-1.534,0.168804,0.00423361,0.453612 kka2_1:4_D101M,kka2_1:4_101,Kka2,kka2_1:4,P00552,,YES,101,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.028,-4.841,3.813,,0.213,E,B,0.75,-1.24,8.707,,63.64,PAH,-1.534,0.168804,0.00423361,0.441311 kka2_1:4_D101P,kka2_1:4_101,Kka2,kka2_1:4,P00552,,YES,101,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.028,-3.843,2.815,,0.213,E,B,0.75,-1.24,8.707,,63.64,PAH,-1.534,0.168804,0.00423361,0.465564 kka2_1:4_D101V,kka2_1:4_101,Kka2,kka2_1:4,P00552,,YES,101,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.028,-2.595,1.567,,0.213,E,B,0.75,-1.24,8.707,,63.64,PAH,-1.534,0.168804,0.00423361,0.602066 kka2_1:4_D101W,kka2_1:4_101,Kka2,kka2_1:4,P00552,,YES,101,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.028,-5.632,4.604,,0.213,E,B,0.75,-1.24,8.707,,63.64,PAH,-1.534,0.168804,0.00423361,0.418527 kka2_1:4_D118A,kka2_1:4_118,Kka2,kka2_1:4,P00552,,YES,118,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.07,-2.21,0.14,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.168804,0.0067852,0.769216 kka2_1:4_D118C,kka2_1:4_118,Kka2,kka2_1:4,P00552,,YES,118,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.07,-5.162,3.092,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.168804,0.0067852,0.706338 kka2_1:4_D118G,kka2_1:4_118,Kka2,kka2_1:4,P00552,,YES,118,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.07,-2.786,0.716,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.168804,0.0067852,0.679864 kka2_1:4_D118M,kka2_1:4_118,Kka2,kka2_1:4,P00552,,YES,118,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.07,-3.354,1.284,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.168804,0.0067852,0.644392 kka2_1:4_D118S,kka2_1:4_118,Kka2,kka2_1:4,P00552,,YES,118,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.07,-2.544,0.474,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.168804,0.0067852,0.72191 kka2_1:4_D118W,kka2_1:4_118,Kka2,kka2_1:4,P00552,,YES,118,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.07,-5.579,3.509,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.168804,0.0067852,0.612678 kka2_1:4_D127C,kka2_1:4_127,Kka2,kka2_1:4,P00552,,YES,127,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.364,-5.181,3.817,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.168804,0.00660501,0.609851 kka2_1:4_D127K,kka2_1:4_127,Kka2,kka2_1:4,P00552,,YES,127,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.364,-3.534,2.17,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.168804,0.00660501,0.599103 kka2_1:4_D127L,kka2_1:4_127,Kka2,kka2_1:4,P00552,,YES,127,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.364,-3.769,2.405,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.168804,0.00660501,0.550601 kka2_1:4_D127M,kka2_1:4_127,Kka2,kka2_1:4,P00552,,YES,127,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.364,-4.921,3.557,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.168804,0.00660501,0.537531 kka2_1:4_D127P,kka2_1:4_127,Kka2,kka2_1:4,P00552,,YES,127,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.364,-1.54,0.176,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.168804,0.00660501,0.735795 kka2_1:4_D127S,kka2_1:4_127,Kka2,kka2_1:4,P00552,,YES,127,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.364,-3.391,2.027,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.168804,0.00660501,0.607125 kka2_1:4_D127T,kka2_1:4_127,Kka2,kka2_1:4,P00552,,YES,127,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.364,-3.566,2.202,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.168804,0.00660501,0.616864 kka2_1:4_D127W,kka2_1:4_127,Kka2,kka2_1:4,P00552,,YES,127,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.364,-5.662,4.298,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.168804,0.00660501,0.50991 kka2_1:4_D134W,kka2_1:4_134,Kka2,kka2_1:4,P00552,,YES,134,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.969,-5.579,4.61,,0.421,B,B,0.75,0.31,0.733,,49.62,HAB,-1.057,0.168804,0.00270812,0.607959 kka2_1:4_D154L,kka2_1:4_154,Kka2,kka2_1:4,P00552,,YES,154,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.876,-3.838,2.962,,0.457,,b,0.29,1.48,15.641,15.641,52.65,HAP,-1.52467,0.168804,0.00292633,0.655927 kka2_1:4_D154P,kka2_1:4_154,Kka2,kka2_1:4,P00552,,YES,154,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.876,-3.765,2.889,,0.457,,b,0.29,1.48,15.641,15.641,52.65,HAP,-1.52467,0.168804,0.00292633,0.664915 kka2_1:4_D154W,kka2_1:4_154,Kka2,kka2_1:4,P00552,,YES,154,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.876,-5.609,4.733,,0.457,,b,0.29,1.48,15.641,15.641,52.65,HAP,-1.52467,0.168804,0.00292633,0.660292 kka2_1:4_D156L,kka2_1:4_156,Kka2,kka2_1:4,P00552,,YES,156,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.696,-3.635,1.939,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.168804,0.00926998,0.79549 kka2_1:4_D157L,kka2_1:4_157,Kka2,kka2_1:4,P00552,,YES,157,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.993,-3.843,2.85,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.168804,0.0042313,0.59214 kka2_1:4_D157M,kka2_1:4_157,Kka2,kka2_1:4,P00552,,YES,157,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.993,-4.965,3.972,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.168804,0.0042313,0.635357 kka2_1:4_D157P,kka2_1:4_157,Kka2,kka2_1:4,P00552,,YES,157,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.993,-3.813,2.82,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.168804,0.0042313,0.608318 kka2_1:4_D157W,kka2_1:4_157,Kka2,kka2_1:4,P00552,,YES,157,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.993,-5.591,4.598,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.168804,0.0042313,0.628696 kka2_1:4_D159S,kka2_1:4_159,Kka2,kka2_1:4,P00552,,YES,159,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.82,-3.223,2.403,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.168804,0.0030485,0.53875 kka2_1:4_D180A,kka2_1:4_180,Kka2,kka2_1:4,P00552,,YES,180,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.416,-2.13,-0.286,,1.03,S,a,0.29,1.5,14.668,14.668,71.59,OAO,-2.02933,0.168804,0.00756412,0.981441 kka2_1:4_D180L,kka2_1:4_180,Kka2,kka2_1:4,P00552,,YES,180,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.416,-2.808,0.392,,1.03,S,a,0.29,1.5,14.668,14.668,71.59,OAO,-2.02933,0.168804,0.00756412,0.890517 kka2_1:4_D180M,kka2_1:4_180,Kka2,kka2_1:4,P00552,,YES,180,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.416,-3.738,1.322,,1.03,S,a,0.29,1.5,14.668,14.668,71.59,OAO,-2.02933,0.168804,0.00756412,0.902431 kka2_1:4_D180P,kka2_1:4_180,Kka2,kka2_1:4,P00552,,YES,180,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.416,-3.147,0.731,,1.03,S,a,0.29,1.5,14.668,14.668,71.59,OAO,-2.02933,0.168804,0.00756412,0.850027 kka2_1:4_D190W,kka2_1:4_190,Kka2,kka2_1:4,P00552,,YES,190,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.708,-5.576,4.868,,0.213,S,b,0.75,-0.82,,,,OAH,-0.711667,0.168804,0.00247989,0.37043 kka2_1:4_D216A,kka2_1:4_216,Kka2,kka2_1:4,P00552,,YES,216,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.785,-3.354,2.569,,0.018,E,B,0.75,-0.51,0.112,,19.32,HAB,-0.970333,0.168804,0.00229969,0.468885 kka2_1:4_D216C,kka2_1:4_216,Kka2,kka2_1:4,P00552,,YES,216,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.785,-5.139,4.354,,0.018,E,B,0.75,-0.51,0.112,,19.32,HAB,-0.970333,0.168804,0.00229969,0.48193 kka2_1:4_D216G,kka2_1:4_216,Kka2,kka2_1:4,P00552,,YES,216,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.785,-3.205,2.42,,0.018,E,B,0.75,-0.51,0.112,,19.32,HAB,-0.970333,0.168804,0.00229969,0.495362 kka2_1:4_D216P,kka2_1:4_216,Kka2,kka2_1:4,P00552,,YES,216,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.785,-3.727,2.942,,0.018,E,B,0.75,-0.51,0.112,,19.32,HAB,-0.970333,0.168804,0.00229969,0.461202 kka2_1:4_D216S,kka2_1:4_216,Kka2,kka2_1:4,P00552,,YES,216,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.785,-3.233,2.448,,0.018,E,B,0.75,-0.51,0.112,,19.32,HAB,-0.970333,0.168804,0.00229969,0.492179 kka2_1:4_D227R,kka2_1:4_227,Kka2,kka2_1:4,P00552,,YES,227,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.758,-3.84,2.082,,0.128,H,A,0.75,-0.63,3.038,,56.06,BAH,-1.43067,0.168804,0.00745029,0.487399 kka2_1:4_D238F,kka2_1:4_238,Kka2,kka2_1:4,P00552,,YES,238,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.83,-4.489,1.659,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.168804,0.0113863,0.927711 kka2_1:4_D238I,kka2_1:4_238,Kka2,kka2_1:4,P00552,,YES,238,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.83,-4.106,1.276,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.168804,0.0113863,0.903353 kka2_1:4_D238M,kka2_1:4_238,Kka2,kka2_1:4,P00552,,YES,238,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.83,-3.594,0.764,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.168804,0.0113863,0.932152 kka2_1:4_D238P,kka2_1:4_238,Kka2,kka2_1:4,P00552,,YES,238,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.83,-2.766,-0.064,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.168804,0.0113863,0.903409 kka2_1:4_D238R,kka2_1:4_238,Kka2,kka2_1:4,P00552,,YES,238,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.83,-2.777,-0.053,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.168804,0.0113863,0.957221 kka2_1:4_D23P,kka2_1:4_23,Kka2,kka2_1:4,P00552,,YES,23,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.459,-3.293,0.834,,0.695,E,B,0.75,-0.65,2.416,,65.53,HAH,-1.94033,0.168804,0.007195,0.7351 kka2_1:4_D23W,kka2_1:4_23,Kka2,kka2_1:4,P00552,,YES,23,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.459,-5.599,3.14,,0.695,E,B,0.75,-0.65,2.416,,65.53,HAH,-1.94033,0.168804,0.007195,0.749541 kka2_1:4_D33M,kka2_1:4_33,Kka2,kka2_1:4,P00552,,YES,33,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.186,-4.904,2.718,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.168804,0.00633568,0.756873 kka2_1:4_D33P,kka2_1:4_33,Kka2,kka2_1:4,P00552,,YES,33,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.186,-2.939,0.753,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.168804,0.00633568,0.714122 kka2_1:4_D33V,kka2_1:4_33,Kka2,kka2_1:4,P00552,,YES,33,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.186,-3.782,1.596,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.168804,0.00633568,0.758694 kka2_1:4_D33W,kka2_1:4_33,Kka2,kka2_1:4,P00552,,YES,33,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.186,-5.589,3.403,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.168804,0.00633568,0.722777 kka2_1:4_D52M,kka2_1:4_52,Kka2,kka2_1:4,P00552,,YES,52,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.271,-4.777,2.506,,0.22,E,B,0.75,0.8,0.349,,71.59,PAH,-2.38367,0.168804,0.00175694,0.74557 kka2_1:4_D52P,kka2_1:4_52,Kka2,kka2_1:4,P00552,,YES,52,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.271,-3.706,1.435,,0.22,E,B,0.75,0.8,0.349,,71.59,PAH,-2.38367,0.168804,0.00175694,0.639998 kka2_1:4_D52Q,kka2_1:4_52,Kka2,kka2_1:4,P00552,,YES,52,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.271,-3.313,1.042,,0.22,E,B,0.75,0.8,0.349,,71.59,PAH,-2.38367,0.168804,0.00175694,0.799147 kka2_1:4_D5C,kka2_1:4_5,Kka2,kka2_1:4,P00552,,YES,5,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.306,-4.968,3.662,,,,,,,,,71.59,PAO,-1.784,0.168804,0.00222864,1.02802 kka2_1:4_D5I,kka2_1:4_5,Kka2,kka2_1:4,P00552,,YES,5,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.306,-3.821,2.515,,,,,,,,,71.59,PAO,-1.784,0.168804,0.00222864,1.0217 kka2_1:4_D5P,kka2_1:4_5,Kka2,kka2_1:4,P00552,,YES,5,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.306,-3.466,2.16,,,,,,,,,71.59,PAO,-1.784,0.168804,0.00222864,1.06923 kka2_1:4_D5W,kka2_1:4_5,Kka2,kka2_1:4,P00552,,YES,5,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.306,-5.278,3.972,,,,,,,,,71.59,PAO,-1.784,0.168804,0.00222864,1.01759 kka2_1:4_D62C,kka2_1:4_62,Kka2,kka2_1:4,P00552,,YES,62,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.591,-5.15,3.559,,0.262,H,A,0.29,0.08,14.756,14.756,64.39,PAA,-1.77833,0.168804,0.00744243,0.512963 kka2_1:4_D62P,kka2_1:4_62,Kka2,kka2_1:4,P00552,,YES,62,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.591,-3.966,2.375,,0.262,H,A,0.29,0.08,14.756,14.756,64.39,PAA,-1.77833,0.168804,0.00744243,0.47526 kka2_1:4_D62R,kka2_1:4_62,Kka2,kka2_1:4,P00552,,YES,62,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.591,-3.972,2.381,,0.262,H,A,0.29,0.08,14.756,14.756,64.39,PAA,-1.77833,0.168804,0.00744243,0.49647 kka2_1:4_D62S,kka2_1:4_62,Kka2,kka2_1:4,P00552,,YES,62,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.591,-3.356,1.765,,0.262,H,A,0.29,0.08,14.756,14.756,64.39,PAA,-1.77833,0.168804,0.00744243,0.520971 kka2_1:4_D62T,kka2_1:4_62,Kka2,kka2_1:4,P00552,,YES,62,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.591,-3.648,2.057,,0.262,H,A,0.29,0.08,14.756,14.756,64.39,PAA,-1.77833,0.168804,0.00744243,0.504458 kka2_1:4_D62V,kka2_1:4_62,Kka2,kka2_1:4,P00552,,YES,62,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.591,-3.746,2.155,,0.262,H,A,0.29,0.08,14.756,14.756,64.39,PAA,-1.77833,0.168804,0.00744243,0.493902 kka2_1:4_D62W,kka2_1:4_62,Kka2,kka2_1:4,P00552,,YES,62,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.591,-5.508,3.917,,0.262,H,A,0.29,0.08,14.756,14.756,64.39,PAA,-1.77833,0.168804,0.00744243,0.449862 kka2_1:4_D82C,kka2_1:4_82,Kka2,kka2_1:4,P00552,,YES,82,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.946,-3.559,1.613,,0.341,E,b,0.75,0.52,11.923,11.923,63.64,HAH,-1.98,0.168804,0.00637516,0.534737 kka2_1:4_D82F,kka2_1:4_82,Kka2,kka2_1:4,P00552,,YES,82,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.946,-4.41,2.464,,0.341,E,b,0.75,0.52,11.923,11.923,63.64,HAH,-1.98,0.168804,0.00637516,0.520986 kka2_1:4_D82M,kka2_1:4_82,Kka2,kka2_1:4,P00552,,YES,82,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.946,-4.849,2.903,,0.341,E,b,0.75,0.52,11.923,11.923,63.64,HAH,-1.98,0.168804,0.00637516,0.564205 kka2_1:4_D82P,kka2_1:4_82,Kka2,kka2_1:4,P00552,,YES,82,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.946,-4.009,2.063,,0.341,E,b,0.75,0.52,11.923,11.923,63.64,HAH,-1.98,0.168804,0.00637516,0.45714 kka2_1:4_D82S,kka2_1:4_82,Kka2,kka2_1:4,P00552,,YES,82,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.946,-2.906,0.96,,0.341,E,b,0.75,0.52,11.923,11.923,63.64,HAH,-1.98,0.168804,0.00637516,0.564635 kka2_1:4_D82W,kka2_1:4_82,Kka2,kka2_1:4,P00552,,YES,82,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.946,-3.611,1.665,,0.341,E,b,0.75,0.52,11.923,11.923,63.64,HAH,-1.98,0.168804,0.00637516,0.507527 kka2_1:4_D90C,kka2_1:4_90,Kka2,kka2_1:4,P00552,,YES,90,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.459,-5.259,2.8,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.168804,0.00583842,0.685692 kka2_1:4_D90L,kka2_1:4_90,Kka2,kka2_1:4,P00552,,YES,90,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.459,-3.657,1.198,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.168804,0.00583842,0.538798 kka2_1:4_D90M,kka2_1:4_90,Kka2,kka2_1:4,P00552,,YES,90,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.459,-4.83,2.371,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.168804,0.00583842,0.587806 kka2_1:4_D90R,kka2_1:4_90,Kka2,kka2_1:4,P00552,,YES,90,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.459,-2.746,0.287,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.168804,0.00583842,0.638212 kka2_1:4_D90S,kka2_1:4_90,Kka2,kka2_1:4,P00552,,YES,90,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.459,-2.612,0.153,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.168804,0.00583842,0.654615 kka2_1:4_D90T,kka2_1:4_90,Kka2,kka2_1:4,P00552,,YES,90,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.459,-3.035,0.576,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.168804,0.00583842,0.593132 kka2_1:4_D90W,kka2_1:4_90,Kka2,kka2_1:4,P00552,,YES,90,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.459,-3.595,1.136,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.168804,0.00583842,0.53334 kka2_1:4_E111C,kka2_1:4_111,Kka2,kka2_1:4,P00552,,YES,111,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.28,-5.229,2.949,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.168804,0.00746789,0.663995 kka2_1:4_E142I,kka2_1:4_142,Kka2,kka2_1:4,P00552,,YES,142,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.221,-4.073,1.852,,0.471,H,A,1.52,0.85,3.693,,65.53,HAB,-2.08033,0.168804,0.00748883,0.676267 kka2_1:4_E142S,kka2_1:4_142,Kka2,kka2_1:4,P00552,,YES,142,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.221,-2.618,0.397,,0.471,H,A,1.52,0.85,3.693,,65.53,HAB,-2.08033,0.168804,0.00748883,0.766496 kka2_1:4_E149C,kka2_1:4_149,Kka2,kka2_1:4,P00552,,YES,149,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.994,-5.217,3.223,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.168804,0.00803343,0.903386 kka2_1:4_E149F,kka2_1:4_149,Kka2,kka2_1:4,P00552,,YES,149,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.994,-4.387,2.393,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.168804,0.00803343,0.949541 kka2_1:4_E149L,kka2_1:4_149,Kka2,kka2_1:4,P00552,,YES,149,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.994,-2.522,0.528,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.168804,0.00803343,0.844601 kka2_1:4_E149M,kka2_1:4_149,Kka2,kka2_1:4,P00552,,YES,149,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.994,-3.564,1.57,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.168804,0.00803343,0.85982 kka2_1:4_E149P,kka2_1:4_149,Kka2,kka2_1:4,P00552,,YES,149,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.994,-4.051,2.057,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.168804,0.00803343,0.802987 kka2_1:4_E149S,kka2_1:4_149,Kka2,kka2_1:4,P00552,,YES,149,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.994,-2.804,0.81,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.168804,0.00803343,0.8554 kka2_1:4_E160L,kka2_1:4_160,Kka2,kka2_1:4,P00552,,YES,160,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.683,-3.761,2.078,,0.989,G,A,1.04,2.28,2.531,,71.59,AAA,-1.36133,0.168804,0.00935762,0.926555 kka2_1:4_E160M,kka2_1:4_160,Kka2,kka2_1:4,P00552,,YES,160,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.683,-4.919,3.236,,0.989,G,A,1.04,2.28,2.531,,71.59,AAA,-1.36133,0.168804,0.00935762,0.90725 kka2_1:4_E160P,kka2_1:4_160,Kka2,kka2_1:4,P00552,,YES,160,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.683,-2.472,0.789,,0.989,G,A,1.04,2.28,2.531,,71.59,AAA,-1.36133,0.168804,0.00935762,0.778411 kka2_1:4_E160S,kka2_1:4_160,Kka2,kka2_1:4,P00552,,YES,160,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.683,-3.324,1.641,,0.989,G,A,1.04,2.28,2.531,,71.59,AAA,-1.36133,0.168804,0.00935762,0.813962 kka2_1:4_E161S,kka2_1:4_161,Kka2,kka2_1:4,P00552,,YES,161,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.581,-2.422,0.841,,0.829,G,A,1.52,2.24,1.612,,92.05,AAB,-1.861,0.168804,0.00760103,0.746748 kka2_1:4_E169G,kka2_1:4_169,Kka2,kka2_1:4,P00552,,YES,169,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.996,-2.941,0.945,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.168804,0.00730086,0.617941 kka2_1:4_E169I,kka2_1:4_169,Kka2,kka2_1:4,P00552,,YES,169,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.996,-4.06,2.064,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.168804,0.00730086,0.660481 kka2_1:4_E169R,kka2_1:4_169,Kka2,kka2_1:4,P00552,,YES,169,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.996,-3.888,1.892,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.168804,0.00730086,0.66694 kka2_1:4_E17I,kka2_1:4_17,Kka2,kka2_1:4,P00552,,YES,17,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.154,-4.159,2.005,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.168804,0.00688738,0.63946 kka2_1:4_E17N,kka2_1:4_17,Kka2,kka2_1:4,P00552,,YES,17,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.154,-3.14,0.986,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.168804,0.00688738,0.766443 kka2_1:4_E17T,kka2_1:4_17,Kka2,kka2_1:4,P00552,,YES,17,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.154,-2.882,0.728,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.168804,0.00688738,0.774507 kka2_1:4_E17V,kka2_1:4_17,Kka2,kka2_1:4,P00552,,YES,17,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.154,-3.778,1.624,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.168804,0.00688738,0.687369 kka2_1:4_E17W,kka2_1:4_17,Kka2,kka2_1:4,P00552,,YES,17,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.154,-5.592,3.438,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.168804,0.00688738,0.640258 kka2_1:4_E17Y,kka2_1:4_17,Kka2,kka2_1:4,P00552,,YES,17,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.154,-4.407,2.253,,0.957,T,A,1.04,0.22,2.567,,63.64,HAB,-2.432,0.168804,0.00688738,0.666045 kka2_1:4_E182C,kka2_1:4_182,Kka2,kka2_1:4,P00552,,YES,182,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.516,-3.433,1.917,,0.326,.,B,1.04,0.75,4.755,,65.53,OAA,-1.806,0.168804,0.00641548,0.511741 kka2_1:4_E182M,kka2_1:4_182,Kka2,kka2_1:4,P00552,,YES,182,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.516,-4.818,3.302,,0.326,.,B,1.04,0.75,4.755,,65.53,OAA,-1.806,0.168804,0.00641548,0.499394 kka2_1:4_E182P,kka2_1:4_182,Kka2,kka2_1:4,P00552,,YES,182,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.516,-3.948,2.432,,0.326,.,B,1.04,0.75,4.755,,65.53,OAA,-1.806,0.168804,0.00641548,0.472857 kka2_1:4_E182W,kka2_1:4_182,Kka2,kka2_1:4,P00552,,YES,182,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.516,-5.341,3.825,,0.326,.,B,1.04,0.75,4.755,,65.53,OAA,-1.806,0.168804,0.00641548,0.483624 kka2_1:4_E235F,kka2_1:4_235,Kka2,kka2_1:4,P00552,,YES,235,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.955,-4.481,2.526,,0.631,H,A,1.04,0.12,23.175,23.175,65.53,OAH,-2.07267,0.168804,0.0102806,0.837688 kka2_1:4_E235M,kka2_1:4_235,Kka2,kka2_1:4,P00552,,YES,235,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.955,-4.796,2.841,,0.631,H,A,1.04,0.12,23.175,23.175,65.53,OAH,-2.07267,0.168804,0.0102806,0.814304 kka2_1:4_E235S,kka2_1:4_235,Kka2,kka2_1:4,P00552,,YES,235,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.955,-2.915,0.96,,0.631,H,A,1.04,0.12,23.175,23.175,65.53,OAH,-2.07267,0.168804,0.0102806,0.660064 kka2_1:4_E262R,kka2_1:4_262,Kka2,kka2_1:4,P00552,,YES,262,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-0.829,-3.509,2.68,,0.059,G,A,1.04,-0.18,2.383,,42.42,AAH,-0.816,0.168804,0.0191586,0.476842 kka2_1:4_E262S,kka2_1:4_262,Kka2,kka2_1:4,P00552,,YES,262,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-0.829,-3.212,2.383,,0.059,G,A,1.04,-0.18,2.383,,42.42,AAH,-0.816,0.168804,0.0191586,0.523868 kka2_1:4_E3M,kka2_1:4_3,Kka2,kka2_1:4,P00552,,YES,3,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.199,-4.633,2.434,,,,,,,7.22,,92.05,HAP,-2.11567,0.168804,0.00267607,1.01845 kka2_1:4_E3S,kka2_1:4_3,Kka2,kka2_1:4,P00552,,YES,3,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.199,-2.253,0.054,,,,,,,7.22,,92.05,HAP,-2.11567,0.168804,0.00267607,1.00394 kka2_1:4_E3T,kka2_1:4_3,Kka2,kka2_1:4,P00552,,YES,3,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.199,-3.32,1.121,,,,,,,7.22,,92.05,HAP,-2.11567,0.168804,0.00267607,1.00216 kka2_1:4_E59A,kka2_1:4_59,Kka2,kka2_1:4,P00552,,YES,59,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-0.952,-3.166,2.214,,0.187,.,L,1.04,0.62,3.408,,50.38,PAH,-1.53,0.168804,0.00280355,0.501133 kka2_1:4_E59C,kka2_1:4_59,Kka2,kka2_1:4,P00552,,YES,59,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-0.952,-5.289,4.337,,0.187,.,L,1.04,0.62,3.408,,50.38,PAH,-1.53,0.168804,0.00280355,0.505013 kka2_1:4_E59H,kka2_1:4_59,Kka2,kka2_1:4,P00552,,YES,59,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-0.952,-4.372,3.42,,0.187,.,L,1.04,0.62,3.408,,50.38,PAH,-1.53,0.168804,0.00280355,0.43789 kka2_1:4_E59M,kka2_1:4_59,Kka2,kka2_1:4,P00552,,YES,59,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-0.952,-4.747,3.795,,0.187,.,L,1.04,0.62,3.408,,50.38,PAH,-1.53,0.168804,0.00280355,0.444412 kka2_1:4_E59N,kka2_1:4_59,Kka2,kka2_1:4,P00552,,YES,59,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-0.952,-3.52,2.568,,0.187,.,L,1.04,0.62,3.408,,50.38,PAH,-1.53,0.168804,0.00280355,0.454934 kka2_1:4_E59S,kka2_1:4_59,Kka2,kka2_1:4,P00552,,YES,59,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-0.952,-3.233,2.281,,0.187,.,L,1.04,0.62,3.408,,50.38,PAH,-1.53,0.168804,0.00280355,0.537987 kka2_1:4_E59T,kka2_1:4_59,Kka2,kka2_1:4,P00552,,YES,59,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-0.952,-2.667,1.715,,0.187,.,L,1.04,0.62,3.408,,50.38,PAH,-1.53,0.168804,0.00280355,0.573807 kka2_1:4_E59W,kka2_1:4_59,Kka2,kka2_1:4,P00552,,YES,59,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-0.952,-5.39,4.438,,0.187,.,L,1.04,0.62,3.408,,50.38,PAH,-1.53,0.168804,0.00280355,0.416848 kka2_1:4_E63C,kka2_1:4_63,Kka2,kka2_1:4,P00552,,YES,63,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-0.762,-5.34,4.578,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.168804,0.00118399,0.465343 kka2_1:4_E63F,kka2_1:4_63,Kka2,kka2_1:4,P00552,,YES,63,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-0.762,-4.32,3.558,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.168804,0.00118399,0.397762 kka2_1:4_E63I,kka2_1:4_63,Kka2,kka2_1:4,P00552,,YES,63,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-0.762,-4.039,3.277,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.168804,0.00118399,0.397831 kka2_1:4_E63M,kka2_1:4_63,Kka2,kka2_1:4,P00552,,YES,63,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-0.762,-4.733,3.971,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.168804,0.00118399,0.431662 kka2_1:4_E63P,kka2_1:4_63,Kka2,kka2_1:4,P00552,,YES,63,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-0.762,-3.683,2.921,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.168804,0.00118399,0.435461 kka2_1:4_E63Q,kka2_1:4_63,Kka2,kka2_1:4,P00552,,YES,63,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-0.762,-3.253,2.491,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.168804,0.00118399,0.441862 kka2_1:4_E63R,kka2_1:4_63,Kka2,kka2_1:4,P00552,,YES,63,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-0.762,-3.511,2.749,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.168804,0.00118399,0.446998 kka2_1:4_E63S,kka2_1:4_63,Kka2,kka2_1:4,P00552,,YES,63,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-0.762,-3.189,2.427,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.168804,0.00118399,0.487435 kka2_1:4_E63T,kka2_1:4_63,Kka2,kka2_1:4,P00552,,YES,63,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-0.762,-3.45,2.688,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.168804,0.00118399,0.455346 kka2_1:4_E63W,kka2_1:4_63,Kka2,kka2_1:4,P00552,,YES,63,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-0.762,-5.351,4.589,,0.043,H,A,1.04,-0.43,,,,AAH,-1.283,0.168804,0.00118399,0.398373 kka2_1:4_E86A,kka2_1:4_86,Kka2,kka2_1:4,P00552,,YES,86,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.86,-2.331,0.471,,0.369,.,B,1.04,1.92,4.451,,63.26,PAH,-1.98067,0.168804,0.00642858,0.663097 kka2_1:4_E86C,kka2_1:4_86,Kka2,kka2_1:4,P00552,,YES,86,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.86,-5.228,3.368,,0.369,.,B,1.04,1.92,4.451,,63.26,PAH,-1.98067,0.168804,0.00642858,0.638963 kka2_1:4_E86I,kka2_1:4_86,Kka2,kka2_1:4,P00552,,YES,86,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.86,-4.165,2.305,,0.369,.,B,1.04,1.92,4.451,,63.26,PAH,-1.98067,0.168804,0.00642858,0.55381 kka2_1:4_E86L,kka2_1:4_86,Kka2,kka2_1:4,P00552,,YES,86,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.86,-3.758,1.898,,0.369,.,B,1.04,1.92,4.451,,63.26,PAH,-1.98067,0.168804,0.00642858,0.586669 kka2_1:4_E86M,kka2_1:4_86,Kka2,kka2_1:4,P00552,,YES,86,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.86,-4.913,3.053,,0.369,.,B,1.04,1.92,4.451,,63.26,PAH,-1.98067,0.168804,0.00642858,0.609367 kka2_1:4_E86N,kka2_1:4_86,Kka2,kka2_1:4,P00552,,YES,86,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.86,-3.654,1.794,,0.369,.,B,1.04,1.92,4.451,,63.26,PAH,-1.98067,0.168804,0.00642858,0.621212 kka2_1:4_E86P,kka2_1:4_86,Kka2,kka2_1:4,P00552,,YES,86,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.86,-3.983,2.123,,0.369,.,B,1.04,1.92,4.451,,63.26,PAH,-1.98067,0.168804,0.00642858,0.541446 kka2_1:4_E86S,kka2_1:4_86,Kka2,kka2_1:4,P00552,,YES,86,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.86,-2.884,1.024,,0.369,.,B,1.04,1.92,4.451,,63.26,PAH,-1.98067,0.168804,0.00642858,0.660548 kka2_1:4_E86T,kka2_1:4_86,Kka2,kka2_1:4,P00552,,YES,86,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.86,-3.681,1.821,,0.369,.,B,1.04,1.92,4.451,,63.26,PAH,-1.98067,0.168804,0.00642858,0.595233 kka2_1:4_E86V,kka2_1:4_86,Kka2,kka2_1:4,P00552,,YES,86,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.86,-3.786,1.926,,0.369,.,B,1.04,1.92,4.451,,63.26,PAH,-1.98067,0.168804,0.00642858,0.592625 kka2_1:4_E86W,kka2_1:4_86,Kka2,kka2_1:4,P00552,,YES,86,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.86,-5.389,3.529,,0.369,.,B,1.04,1.92,4.451,,63.26,PAH,-1.98067,0.168804,0.00642858,0.59246 kka2_1:4_E96C,kka2_1:4_96,Kka2,kka2_1:4,P00552,,YES,96,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.573,-4.752,2.179,,0.476,,B,1.52,-0.65,1.254,,71.59,OAH,-2.143,0.168804,0.00369441,0.661285 kka2_1:4_E96S,kka2_1:4_96,Kka2,kka2_1:4,P00552,,YES,96,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.573,-3.194,0.621,,0.476,,B,1.52,-0.65,1.254,,71.59,OAH,-2.143,0.168804,0.00369441,0.661493 kka2_1:4_F133A,kka2_1:4_133,Kka2,kka2_1:4,P00552,,YES,133,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-0.871,-3.354,2.483,,0.178,.,B,0.58,0.43,0.786,,42.42,OHA,-0.871667,0.168804,0.00182168,0.473121 kka2_1:4_F133E,kka2_1:4_133,Kka2,kka2_1:4,P00552,,YES,133,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-0.871,-3.916,3.045,,0.178,.,B,0.58,0.43,0.786,,42.42,OHA,-0.871667,0.168804,0.00182168,0.413871 kka2_1:4_F133G,kka2_1:4_133,Kka2,kka2_1:4,P00552,,YES,133,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-0.871,-3.635,2.764,,0.178,.,B,0.58,0.43,0.786,,42.42,OHA,-0.871667,0.168804,0.00182168,0.487303 kka2_1:4_F133N,kka2_1:4_133,Kka2,kka2_1:4,P00552,,YES,133,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-0.871,-4.149,3.278,,0.178,.,B,0.58,0.43,0.786,,42.42,OHA,-0.871667,0.168804,0.00182168,0.418358 kka2_1:4_F133P,kka2_1:4_133,Kka2,kka2_1:4,P00552,,YES,133,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-0.871,-4.356,3.485,,0.178,.,B,0.58,0.43,0.786,,42.42,OHA,-0.871667,0.168804,0.00182168,0.466545 kka2_1:4_F133T,kka2_1:4_133,Kka2,kka2_1:4,P00552,,YES,133,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-0.871,-3.698,2.827,,0.178,.,B,0.58,0.43,0.786,,42.42,OHA,-0.871667,0.168804,0.00182168,0.467868 kka2_1:4_F171A,kka2_1:4_171,Kka2,kka2_1:4,P00552,,YES,171,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.326,-3.394,2.068,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.168804,0.00821426,0.453034 kka2_1:4_F171D,kka2_1:4_171,Kka2,kka2_1:4,P00552,,YES,171,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.326,-4.095,2.769,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.168804,0.00821426,0.400865 kka2_1:4_F171H,kka2_1:4_171,Kka2,kka2_1:4,P00552,,YES,171,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.326,-3.195,1.869,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.168804,0.00821426,0.436013 kka2_1:4_F171P,kka2_1:4_171,Kka2,kka2_1:4,P00552,,YES,171,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.326,-4.354,3.028,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.168804,0.00821426,0.434848 kka2_1:4_F171Q,kka2_1:4_171,Kka2,kka2_1:4,P00552,,YES,171,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.326,-4.325,2.999,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.168804,0.00821426,0.428723 kka2_1:4_F171R,kka2_1:4_171,Kka2,kka2_1:4,P00552,,YES,171,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.326,-4.175,2.849,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.168804,0.00821426,0.485251 kka2_1:4_F206R,kka2_1:4_206,Kka2,kka2_1:4,P00552,,YES,206,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.349,-4.172,2.823,,0.006,E,B,0.58,-1.21,1.342,,63.64,OHH,-1.04,0.168804,0.00936868,0.47728 kka2_1:4_F20A,kka2_1:4_20,Kka2,kka2_1:4,P00552,,YES,20,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-3.354,-1.671,-1.683,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.168804,0.00701744,1.07649 kka2_1:4_F20G,kka2_1:4_20,Kka2,kka2_1:4,P00552,,YES,20,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-3.354,-2.338,-1.016,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.168804,0.00701744,1.0564 kka2_1:4_F20I,kka2_1:4_20,Kka2,kka2_1:4,P00552,,YES,20,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-3.354,-3.918,0.564,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.168804,0.00701744,0.895193 kka2_1:4_F20K,kka2_1:4_20,Kka2,kka2_1:4,P00552,,YES,20,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-3.354,-2.992,-0.362,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.168804,0.00701744,1.01282 kka2_1:4_F20N,kka2_1:4_20,Kka2,kka2_1:4,P00552,,YES,20,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-3.354,-3.854,0.5,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.168804,0.00701744,0.936444 kka2_1:4_F20P,kka2_1:4_20,Kka2,kka2_1:4,P00552,,YES,20,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-3.354,-2.906,-0.448,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.168804,0.00701744,0.989338 kka2_1:4_F20R,kka2_1:4_20,Kka2,kka2_1:4,P00552,,YES,20,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-3.354,-2.757,-0.597,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.168804,0.00701744,1.06839 kka2_1:4_F20T,kka2_1:4_20,Kka2,kka2_1:4,P00552,,YES,20,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-3.354,-2.596,-0.758,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.168804,0.00701744,1.07603 kka2_1:4_F20W,kka2_1:4_20,Kka2,kka2_1:4,P00552,,YES,20,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-3.354,-5.49,2.136,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.168804,0.00701744,0.948255 kka2_1:4_F240A,kka2_1:4_240,Kka2,kka2_1:4,P00552,,YES,240,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-0.911,-3.329,2.418,,,H,A,0.58,-1.21,5.798,,50.38,BHH,-1.67267,0.168804,0.00552543,0.439469 kka2_1:4_F240D,kka2_1:4_240,Kka2,kka2_1:4,P00552,,YES,240,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-0.911,-4.011,3.1,,,H,A,0.58,-1.21,5.798,,50.38,BHH,-1.67267,0.168804,0.00552543,0.374318 kka2_1:4_F240K,kka2_1:4_240,Kka2,kka2_1:4,P00552,,YES,240,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-0.911,-3.934,3.023,,,H,A,0.58,-1.21,5.798,,50.38,BHH,-1.67267,0.168804,0.00552543,0.37451 kka2_1:4_F256R,kka2_1:4_256,Kka2,kka2_1:4,P00552,,YES,256,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.49,-3.099,1.609,,,H,A,0.58,-0.78,1.653,,53.03,HHH,-1.423,0.168804,0.0132841,0.496035 kka2_1:4_F263A,kka2_1:4_263,Kka2,kka2_1:4,P00552,,YES,263,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-0.911,-3.329,2.418,,0.006,G,A,0.58,-0.12,2.284,,45.83,AHH,-0.92,0.168804,0.0172454,0.41052 kka2_1:4_F263D,kka2_1:4_263,Kka2,kka2_1:4,P00552,,YES,263,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-0.911,-4.011,3.1,,0.006,G,A,0.58,-0.12,2.284,,45.83,AHH,-0.92,0.168804,0.0172454,0.389456 kka2_1:4_F264R,kka2_1:4_264,Kka2,kka2_1:4,P00552,,YES,264,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.02,-4.192,3.172,,0.296,,?,1.62,0.02,1.93,,71.59,HHO,-0.9655,0.168804,,0.470445 kka2_1:4_F37C,kka2_1:4_37,Kka2,kka2_1:4,P00552,,YES,37,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.427,-4.988,3.561,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.168804,0.00586193,0.538971 kka2_1:4_F37E,kka2_1:4_37,Kka2,kka2_1:4,P00552,,YES,37,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.427,-3.871,2.444,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.168804,0.00586193,0.403793 kka2_1:4_F37K,kka2_1:4_37,Kka2,kka2_1:4,P00552,,YES,37,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.427,-3.907,2.48,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.168804,0.00586193,0.413283 kka2_1:4_F37N,kka2_1:4_37,Kka2,kka2_1:4,P00552,,YES,37,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.427,-4.089,2.662,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.168804,0.00586193,0.397089 kka2_1:4_F37P,kka2_1:4_37,Kka2,kka2_1:4,P00552,,YES,37,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.427,-4.289,2.862,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.168804,0.00586193,0.439441 kka2_1:4_F37T,kka2_1:4_37,Kka2,kka2_1:4,P00552,,YES,37,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.427,-3.702,2.275,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.168804,0.00586193,0.474474 kka2_1:4_F48D,kka2_1:4_48,Kka2,kka2_1:4,P00552,,YES,48,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.453,-4.107,2.654,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.168804,0.00475422,0.374658 kka2_1:4_F48G,kka2_1:4_48,Kka2,kka2_1:4,P00552,,YES,48,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.453,-3.796,2.343,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.168804,0.00475422,0.435284 kka2_1:4_F48N,kka2_1:4_48,Kka2,kka2_1:4,P00552,,YES,48,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.453,-4.244,2.791,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.168804,0.00475422,0.362155 kka2_1:4_F48P,kka2_1:4_48,Kka2,kka2_1:4,P00552,,YES,48,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.453,-4.319,2.866,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.168804,0.00475422,0.415301 kka2_1:4_F48T,kka2_1:4_48,Kka2,kka2_1:4,P00552,,YES,48,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.453,-3.684,2.231,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.168804,0.00475422,0.446251 kka2_1:4_F48Y,kka2_1:4_48,Kka2,kka2_1:4,P00552,,YES,48,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.453,-1.946,0.493,,0.296,E,B,0.58,-0.99,1.93,,55.3,HHH,-1.444,0.168804,0.00475422,0.556828 kka2_1:4_G10Y,kka2_1:4_10,Kka2,kka2_1:4,P00552,,YES,10,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.921,-4.276,2.355,,,,,,,1.862,,71.59,HOP,-2.10733,0.168804,0.00289233,0.898331 kka2_1:4_G151H,kka2_1:4_151,Kka2,kka2_1:4,P00552,,YES,151,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.873,-4.645,3.772,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.168804,0.00339918,0.572718 kka2_1:4_G151P,kka2_1:4_151,Kka2,kka2_1:4,P00552,,YES,151,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.873,-3.953,3.08,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.168804,0.00339918,0.550935 kka2_1:4_G164M,kka2_1:4_164,Kka2,kka2_1:4,P00552,,YES,164,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.869,-4.95,4.081,,0.862,T,l,0.75,1.45,1.539,,64.39,POH,-1.828,0.168804,0.00442091,0.659603 kka2_1:4_G181M,kka2_1:4_181,Kka2,kka2_1:4,P00552,,YES,181,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-2.698,-4.828,2.13,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.168804,0.00728319,0.931527 kka2_1:4_G201T,kka2_1:4_201,Kka2,kka2_1:4,P00552,,YES,201,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.56,-3.028,1.468,,0.149,T,l,0.29,-0.57,0.284,,52.65,POB,-1.92233,0.168804,0.00820117,0.511685 kka2_1:4_G205P,kka2_1:4_205,Kka2,kka2_1:4,P00552,,YES,205,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.596,-3.908,3.312,,,E,b,0.29,-1.05,,,,POH,-1.09933,0.168804,0.00221855,0.442055 kka2_1:4_G21M,kka2_1:4_21,Kka2,kka2_1:4,P00552,,YES,21,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.368,-4.924,3.556,,0.586,T,l,0.75,-0.75,3.075,,71.59,HOH,-2.10167,0.168804,0.00709648,0.724335 kka2_1:4_G21P,kka2_1:4_21,Kka2,kka2_1:4,P00552,,YES,21,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.368,-3.965,2.597,,0.586,T,l,0.75,-0.75,3.075,,71.59,HOH,-2.10167,0.168804,0.00709648,0.660413 kka2_1:4_G21W,kka2_1:4_21,Kka2,kka2_1:4,P00552,,YES,21,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.368,-5.423,4.055,,0.586,T,l,0.75,-0.75,3.075,,71.59,HOH,-2.10167,0.168804,0.00709648,0.683711 kka2_1:4_G21Y,kka2_1:4_21,Kka2,kka2_1:4,P00552,,YES,21,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.368,-4.271,2.903,,0.586,T,l,0.75,-0.75,3.075,,71.59,HOH,-2.10167,0.168804,0.00709648,0.690721 kka2_1:4_G245I,kka2_1:4_245,Kka2,kka2_1:4,P00552,,YES,245,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.812,-4.212,3.4,,0.655,T,g,0.29,0.03,1.468,,65.53,HOH,-1.19833,0.168804,0.00683899,0.469003 kka2_1:4_G30K,kka2_1:4_30,Kka2,kka2_1:4,P00552,,YES,30,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.596,-3.71,3.114,,0.54,S,g,0.29,3.76,,,,HOO,-1.51133,0.168804,0.00159208,0.425462 kka2_1:4_G30M,kka2_1:4_30,Kka2,kka2_1:4,P00552,,YES,30,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.596,-4.958,4.362,,0.54,S,g,0.29,3.76,,,,HOO,-1.51133,0.168804,0.00159208,0.462305 kka2_1:4_G43H,kka2_1:4_43,Kka2,kka2_1:4,P00552,,YES,43,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.587,-4.654,3.067,,0.862,T,l,0.75,-0.67,2.247,,63.26,POB,-2.18533,0.168804,0.0071925,0.692632 kka2_1:4_G43L,kka2_1:4_43,Kka2,kka2_1:4,P00552,,YES,43,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.587,-3.778,2.191,,0.862,T,l,0.75,-0.67,2.247,,63.26,POB,-2.18533,0.168804,0.0071925,0.660197 kka2_1:4_G43N,kka2_1:4_43,Kka2,kka2_1:4,P00552,,YES,43,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.587,-2.611,1.024,,0.862,T,l,0.75,-0.67,2.247,,63.26,POB,-2.18533,0.168804,0.0071925,0.820601 kka2_1:4_G43Q,kka2_1:4_43,Kka2,kka2_1:4,P00552,,YES,43,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.587,-3.198,1.611,,0.862,T,l,0.75,-0.67,2.247,,63.26,POB,-2.18533,0.168804,0.0071925,0.756277 kka2_1:4_G55I,kka2_1:4_55,Kka2,kka2_1:4,P00552,,YES,55,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.625,-3.229,1.604,,0.517,S,b,0.75,1.19,15.753,15.753,63.64,POH,-2.05967,0.168804,0.00667877,0.628955 kka2_1:4_G55Y,kka2_1:4_55,Kka2,kka2_1:4,P00552,,YES,55,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.625,-4.276,2.651,,0.517,S,b,0.75,1.19,15.753,15.753,63.64,POH,-2.05967,0.168804,0.00667877,0.5762 kka2_1:4_G6I,kka2_1:4_6,Kka2,kka2_1:4,P00552,,YES,6,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.685,-3.841,2.156,,,,,,,,,71.59,AOH,-1.639,0.168804,0.00204693,1.04477 kka2_1:4_G88F,kka2_1:4_88,Kka2,kka2_1:4,P00552,,YES,88,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.689,-4.477,2.788,,0.54,S,l,0.29,1.51,7.899,,65.53,HOB,-1.718,0.168804,0.00685559,0.617181 kka2_1:4_G88H,kka2_1:4_88,Kka2,kka2_1:4,P00552,,YES,88,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.689,-3.199,1.51,,0.54,S,l,0.29,1.51,7.899,,65.53,HOB,-1.718,0.168804,0.00685559,0.660123 kka2_1:4_G88K,kka2_1:4_88,Kka2,kka2_1:4,P00552,,YES,88,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.689,-3.033,1.344,,0.54,S,l,0.29,1.51,7.899,,65.53,HOB,-1.718,0.168804,0.00685559,0.681187 kka2_1:4_G88M,kka2_1:4_88,Kka2,kka2_1:4,P00552,,YES,88,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.689,-4.913,3.224,,0.54,S,l,0.29,1.51,7.899,,65.53,HOB,-1.718,0.168804,0.00685559,0.644766 kka2_1:4_G88P,kka2_1:4_88,Kka2,kka2_1:4,P00552,,YES,88,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.689,-4.037,2.348,,0.54,S,l,0.29,1.51,7.899,,65.53,HOB,-1.718,0.168804,0.00685559,0.576237 kka2_1:4_G88Q,kka2_1:4_88,Kka2,kka2_1:4,P00552,,YES,88,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.689,-2.821,1.132,,0.54,S,l,0.29,1.51,7.899,,65.53,HOB,-1.718,0.168804,0.00685559,0.697649 kka2_1:4_G88W,kka2_1:4_88,Kka2,kka2_1:4,P00552,,YES,88,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.689,-5.544,3.855,,0.54,S,l,0.29,1.51,7.899,,65.53,HOB,-1.718,0.168804,0.00685559,0.621556 kka2_1:4_G99P,kka2_1:4_99,Kka2,kka2_1:4,P00552,,YES,99,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.596,-3.908,3.312,,0.368,S,g,0.29,-0.87,,,,OOP,-1.63067,0.168804,0.00186055,0.465912 kka2_1:4_H106C,kka2_1:4_106,Kka2,kka2_1:4,P00552,,YES,106,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-3.13,-5.214,2.084,,1.065,.,a,0.17,-0.95,16.74,16.74,71.59,PBH,-2.10433,0.168804,0.00730778,0.91836 kka2_1:4_H106G,kka2_1:4_106,Kka2,kka2_1:4,P00552,,YES,106,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-3.13,-2.689,-0.441,,1.065,.,a,0.17,-0.95,16.74,16.74,71.59,PBH,-2.10433,0.168804,0.00730778,1.02038 kka2_1:4_H106M,kka2_1:4_106,Kka2,kka2_1:4,P00552,,YES,106,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-3.13,-4.852,1.722,,1.065,.,a,0.17,-0.95,16.74,16.74,71.59,PBH,-2.10433,0.168804,0.00730778,0.7448 kka2_1:4_H106S,kka2_1:4_106,Kka2,kka2_1:4,P00552,,YES,106,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-3.13,-2.484,-0.646,,1.065,.,a,0.17,-0.95,16.74,16.74,71.59,PBH,-2.10433,0.168804,0.00730778,1.03694 kka2_1:4_H106T,kka2_1:4_106,Kka2,kka2_1:4,P00552,,YES,106,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-3.13,-2.51,-0.62,,1.065,.,a,0.17,-0.95,16.74,16.74,71.59,PBH,-2.10433,0.168804,0.00730778,1.03847 kka2_1:4_H124A,kka2_1:4_124,Kka2,kka2_1:4,P00552,,YES,124,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-0.84,-3.331,2.491,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.168804,0.00211296,0.429197 kka2_1:4_H124C,kka2_1:4_124,Kka2,kka2_1:4,P00552,,YES,124,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-0.84,-5.115,4.275,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.168804,0.00211296,0.462053 kka2_1:4_H124E,kka2_1:4_124,Kka2,kka2_1:4,P00552,,YES,124,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-0.84,-3.243,2.403,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.168804,0.00211296,0.453287 kka2_1:4_H124F,kka2_1:4_124,Kka2,kka2_1:4,P00552,,YES,124,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-0.84,-3.87,3.03,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.168804,0.00211296,0.425668 kka2_1:4_H124L,kka2_1:4_124,Kka2,kka2_1:4,P00552,,YES,124,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-0.84,-3.611,2.771,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.168804,0.00211296,0.446499 kka2_1:4_H124M,kka2_1:4_124,Kka2,kka2_1:4,P00552,,YES,124,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-0.84,-4.733,3.893,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.168804,0.00211296,0.449099 kka2_1:4_H124S,kka2_1:4_124,Kka2,kka2_1:4,P00552,,YES,124,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-0.84,-3.414,2.574,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.168804,0.00211296,0.455974 kka2_1:4_H124V,kka2_1:4_124,Kka2,kka2_1:4,P00552,,YES,124,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-0.84,-3.782,2.942,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.168804,0.00211296,0.433872 kka2_1:4_H124W,kka2_1:4_124,Kka2,kka2_1:4,P00552,,YES,124,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-0.84,-5.126,4.286,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.168804,0.00211296,0.407555 kka2_1:4_H139A,kka2_1:4_139,Kka2,kka2_1:4,P00552,,YES,139,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-2.809,-2.449,-0.36,,0.471,H,A,0.17,0.68,12.761,12.761,63.64,BBB,-2.22,0.168804,0.00734779,0.880522 kka2_1:4_H139E,kka2_1:4_139,Kka2,kka2_1:4,P00552,,YES,139,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-2.809,-2.979,0.17,,0.471,H,A,0.17,0.68,12.761,12.761,63.64,BBB,-2.22,0.168804,0.00734779,0.812169 kka2_1:4_H139M,kka2_1:4_139,Kka2,kka2_1:4,P00552,,YES,139,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-2.809,-3.708,0.899,,0.471,H,A,0.17,0.68,12.761,12.761,63.64,BBB,-2.22,0.168804,0.00734779,0.749169 kka2_1:4_H139V,kka2_1:4_139,Kka2,kka2_1:4,P00552,,YES,139,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-2.809,-2.837,0.028,,0.471,H,A,0.17,0.68,12.761,12.761,63.64,BBB,-2.22,0.168804,0.00734779,0.822573 kka2_1:4_H139W,kka2_1:4_139,Kka2,kka2_1:4,P00552,,YES,139,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-2.809,-5.517,2.708,,0.471,H,A,0.17,0.68,12.761,12.761,63.64,BBB,-2.22,0.168804,0.00734779,0.856013 kka2_1:4_H162A,kka2_1:4_162,Kka2,kka2_1:4,P00552,,YES,162,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-2.319,-3.316,0.997,,0.071,G,A,0.17,1.01,3.187,,64.39,ABP,-2.02067,0.168804,0.00616145,0.486333 kka2_1:4_H162G,kka2_1:4_162,Kka2,kka2_1:4,P00552,,YES,162,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-2.319,-3.406,1.087,,0.071,G,A,0.17,1.01,3.187,,64.39,ABP,-2.02067,0.168804,0.00616145,0.475052 kka2_1:4_H162S,kka2_1:4_162,Kka2,kka2_1:4,P00552,,YES,162,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-2.319,-3.471,1.152,,0.071,G,A,0.17,1.01,3.187,,64.39,ABP,-2.02067,0.168804,0.00616145,0.509614 kka2_1:4_H162T,kka2_1:4_162,Kka2,kka2_1:4,P00552,,YES,162,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-2.319,-3.571,1.252,,0.071,G,A,0.17,1.01,3.187,,64.39,ABP,-2.02067,0.168804,0.00616145,0.486591 kka2_1:4_H162W,kka2_1:4_162,Kka2,kka2_1:4,P00552,,YES,162,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-2.319,-2.828,0.509,,0.071,G,A,0.17,1.01,3.187,,64.39,ABP,-2.02067,0.168804,0.00616145,0.595442 kka2_1:4_H8M,kka2_1:4_8,Kka2,kka2_1:4,P00552,,YES,8,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-2.759,-4.438,1.679,,,,,,,,,71.59,HBH,-2.25467,0.168804,0.00256422,1.02057 kka2_1:4_H8P,kka2_1:4_8,Kka2,kka2_1:4,P00552,,YES,8,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-2.759,-3.809,1.05,,,,,,,,,71.59,HBH,-2.25467,0.168804,0.00256422,0.960864 kka2_1:4_H8S,kka2_1:4_8,Kka2,kka2_1:4,P00552,,YES,8,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-2.759,-2.388,-0.371,,,,,,,,,71.59,HBH,-2.25467,0.168804,0.00256422,1.05279 kka2_1:4_I141A,kka2_1:4_141,Kka2,kka2_1:4,P00552,,YES,141,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.495,-3.207,1.712,,0.068,H,A,0.48,-0.01,2.144,,92.05,BHA,-1.689,0.168804,0.00744745,0.448095 kka2_1:4_I141G,kka2_1:4_141,Kka2,kka2_1:4,P00552,,YES,141,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.495,-3.916,2.421,,0.068,H,A,0.48,-0.01,2.144,,92.05,BHA,-1.689,0.168804,0.00744745,0.483811 kka2_1:4_I141P,kka2_1:4_141,Kka2,kka2_1:4,P00552,,YES,141,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.495,-4.213,2.718,,0.068,H,A,0.48,-0.01,2.144,,92.05,BHA,-1.689,0.168804,0.00744745,0.477119 kka2_1:4_I141R,kka2_1:4_141,Kka2,kka2_1:4,P00552,,YES,141,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.495,-4.204,2.709,,0.068,H,A,0.48,-0.01,2.144,,92.05,BHA,-1.689,0.168804,0.00744745,0.540358 kka2_1:4_I141W,kka2_1:4_141,Kka2,kka2_1:4,P00552,,YES,141,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.495,-5.368,3.873,,0.068,H,A,0.48,-0.01,2.144,,92.05,BHA,-1.689,0.168804,0.00744745,0.470961 kka2_1:4_I221A,kka2_1:4_221,Kka2,kka2_1:4,P00552,,YES,221,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.739,-3.216,1.477,,,H,A,0.48,-1.15,1.751,,71.59,AHH,-1.08367,0.168804,0.00945908,0.473475 kka2_1:4_I246D,kka2_1:4_246,Kka2,kka2_1:4,P00552,,YES,246,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-2.008,-3.218,1.21,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.168804,0.0139479,0.572271 kka2_1:4_I246F,kka2_1:4_246,Kka2,kka2_1:4,P00552,,YES,246,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-2.008,-3.274,1.266,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.168804,0.0139479,0.581035 kka2_1:4_I246G,kka2_1:4_246,Kka2,kka2_1:4,P00552,,YES,246,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-2.008,-2.463,0.455,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.168804,0.0139479,0.720992 kka2_1:4_I246Q,kka2_1:4_246,Kka2,kka2_1:4,P00552,,YES,246,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-2.008,-4.292,2.284,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.168804,0.0139479,0.689669 kka2_1:4_I246W,kka2_1:4_246,Kka2,kka2_1:4,P00552,,YES,246,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-2.008,-5.452,3.444,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.168804,0.0139479,0.649654 kka2_1:4_I254R,kka2_1:4_254,Kka2,kka2_1:4,P00552,,YES,254,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.933,-3.154,1.221,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.168804,0.0132375,0.525438 kka2_1:4_I29C,kka2_1:4_29,Kka2,kka2_1:4,P00552,,YES,29,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.692,-4.988,3.296,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.168804,0.00619521,0.706131 kka2_1:4_I29E,kka2_1:4_29,Kka2,kka2_1:4,P00552,,YES,29,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.692,-2.793,1.101,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.168804,0.00619521,0.784862 kka2_1:4_I29G,kka2_1:4_29,Kka2,kka2_1:4,P00552,,YES,29,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.692,-2.967,1.275,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.168804,0.00619521,0.789246 kka2_1:4_I29P,kka2_1:4_29,Kka2,kka2_1:4,P00552,,YES,29,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.692,-4.154,2.462,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.168804,0.00619521,0.629387 kka2_1:4_I29W,kka2_1:4_29,Kka2,kka2_1:4,P00552,,YES,29,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.692,-5.447,3.755,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.168804,0.00619521,0.660386 kka2_1:4_I2A,kka2_1:4_2,Kka2,kka2_1:4,P00552,,YES,2,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.787,-2.783,0.996,,,,,,,,,71.59,HHA,-1.92433,0.168804,0.00246644,0.968055 kka2_1:4_K112A,kka2_1:4_112,Kka2,kka2_1:4,P00552,,YES,112,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-2.491,-2.624,0.133,,0.076,H,A,2.34,-1.37,0.39,,56.06,ABH,-2.00133,0.168804,0.00645389,0.511366 kka2_1:4_K112G,kka2_1:4_112,Kka2,kka2_1:4,P00552,,YES,112,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-2.491,-3.699,1.208,,0.076,H,A,2.34,-1.37,0.39,,56.06,ABH,-2.00133,0.168804,0.00645389,0.382641 kka2_1:4_K112V,kka2_1:4_112,Kka2,kka2_1:4,P00552,,YES,112,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-2.491,-2.276,-0.215,,0.076,H,A,2.34,-1.37,0.39,,56.06,ABH,-2.00133,0.168804,0.00645389,0.564214 kka2_1:4_K138A,kka2_1:4_138,Kka2,kka2_1:4,P00552,,YES,138,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-2.5,-2.407,-0.093,,0.594,H,A,1.3,0.98,21.267,21.267,71.59,HBB,-2.48833,0.168804,0.00628542,0.886462 kka2_1:4_K138P,kka2_1:4_138,Kka2,kka2_1:4,P00552,,YES,138,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-2.5,-3.19,0.69,,0.594,H,A,1.3,0.98,21.267,21.267,71.59,HBB,-2.48833,0.168804,0.00628542,0.764306 kka2_1:4_K175F,kka2_1:4_175,Kka2,kka2_1:4,P00552,,YES,175,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-2.897,-4.186,1.289,,0.579,H,A,1.3,0.51,15.629,15.629,71.59,HBH,-1.82333,0.168804,0.00693093,0.792532 kka2_1:4_K175L,kka2_1:4_175,Kka2,kka2_1:4,P00552,,YES,175,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-2.897,-1.898,-0.999,,0.579,H,A,1.3,0.51,15.629,15.629,71.59,HBH,-1.82333,0.168804,0.00693093,0.978452 kka2_1:4_K175W,kka2_1:4_175,Kka2,kka2_1:4,P00552,,YES,175,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-2.897,-5.429,2.532,,0.579,H,A,1.3,0.51,15.629,15.629,71.59,HBH,-1.82333,0.168804,0.00693093,0.840232 kka2_1:4_K50C,kka2_1:4_50,Kka2,kka2_1:4,P00552,,YES,50,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-0.833,-5.139,4.306,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.168804,0.00138626,0.502108 kka2_1:4_K50F,kka2_1:4_50,Kka2,kka2_1:4,P00552,,YES,50,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-0.833,-4.344,3.511,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.168804,0.00138626,0.420216 kka2_1:4_K50G,kka2_1:4_50,Kka2,kka2_1:4,P00552,,YES,50,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-0.833,-3.41,2.577,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.168804,0.00138626,0.501341 kka2_1:4_K50M,kka2_1:4_50,Kka2,kka2_1:4,P00552,,YES,50,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-0.833,-4.531,3.698,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.168804,0.00138626,0.432874 kka2_1:4_K50P,kka2_1:4_50,Kka2,kka2_1:4,P00552,,YES,50,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-0.833,-3.727,2.894,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.168804,0.00138626,0.462259 kka2_1:4_K50W,kka2_1:4_50,Kka2,kka2_1:4,P00552,,YES,50,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-0.833,-5.374,4.541,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.168804,0.00138626,0.393929 kka2_1:4_K50Y,kka2_1:4_50,Kka2,kka2_1:4,P00552,,YES,50,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-0.833,-4.214,3.381,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.168804,0.00138626,0.435214 kka2_1:4_L102A,kka2_1:4_102,Kka2,kka2_1:4,P00552,,YES,102,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.804,-3.129,2.325,,,T,A,0.55,-1.17,0.65,,42.42,AHH,-1.398,0.168804,0.00201332,0.468741 kka2_1:4_L102G,kka2_1:4_102,Kka2,kka2_1:4,P00552,,YES,102,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.804,-3.835,3.031,,,T,A,0.55,-1.17,0.65,,42.42,AHH,-1.398,0.168804,0.00201332,0.432124 kka2_1:4_L102K,kka2_1:4_102,Kka2,kka2_1:4,P00552,,YES,102,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.804,-3.708,2.904,,,T,A,0.55,-1.17,0.65,,42.42,AHH,-1.398,0.168804,0.00201332,0.407425 kka2_1:4_L102N,kka2_1:4_102,Kka2,kka2_1:4,P00552,,YES,102,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.804,-4.149,3.345,,,T,A,0.55,-1.17,0.65,,42.42,AHH,-1.398,0.168804,0.00201332,0.40565 kka2_1:4_L102T,kka2_1:4_102,Kka2,kka2_1:4,P00552,,YES,102,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.804,-3.473,2.669,,,T,A,0.55,-1.17,0.65,,42.42,AHH,-1.398,0.168804,0.00201332,0.471473 kka2_1:4_L102W,kka2_1:4_102,Kka2,kka2_1:4,P00552,,YES,102,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.804,-5.124,4.32,,,T,A,0.55,-1.17,0.65,,42.42,AHH,-1.398,0.168804,0.00201332,0.376498 kka2_1:4_L103E,kka2_1:4_103,Kka2,kka2_1:4,P00552,,YES,103,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-2.362,-2.689,0.327,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.168804,0.00574792,0.62312 kka2_1:4_L103S,kka2_1:4_103,Kka2,kka2_1:4,P00552,,YES,103,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-2.362,-2.565,0.203,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.168804,0.00574792,0.65564 kka2_1:4_L103Y,kka2_1:4_103,Kka2,kka2_1:4,P00552,,YES,103,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-2.362,-4.297,1.935,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.168804,0.00574792,0.617146 kka2_1:4_L107G,kka2_1:4_107,Kka2,kka2_1:4,P00552,,YES,107,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.238,-3.822,2.584,,0.197,.,B,0.55,-1.1,0.398,,71.59,BHH,-2.143,0.168804,0.00561937,0.507839 kka2_1:4_L123C,kka2_1:4_123,Kka2,kka2_1:4,P00552,,YES,123,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.888,-4.72,3.832,,0.007,H,A,0.55,-0.4,1.447,,48.86,BHB,-1.301,0.168804,0.00325188,0.511022 kka2_1:4_L123D,kka2_1:4_123,Kka2,kka2_1:4,P00552,,YES,123,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.888,-4.173,3.285,,0.007,H,A,0.55,-0.4,1.447,,48.86,BHB,-1.301,0.168804,0.00325188,0.393029 kka2_1:4_L123E,kka2_1:4_123,Kka2,kka2_1:4,P00552,,YES,123,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.888,-3.94,3.052,,0.007,H,A,0.55,-0.4,1.447,,48.86,BHB,-1.301,0.168804,0.00325188,0.382866 kka2_1:4_L123F,kka2_1:4_123,Kka2,kka2_1:4,P00552,,YES,123,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.888,-3.7,2.812,,0.007,H,A,0.55,-0.4,1.447,,48.86,BHB,-1.301,0.168804,0.00325188,0.384518 kka2_1:4_L123G,kka2_1:4_123,Kka2,kka2_1:4,P00552,,YES,123,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.888,-3.859,2.971,,0.007,H,A,0.55,-0.4,1.447,,48.86,BHB,-1.301,0.168804,0.00325188,0.44172 kka2_1:4_L123K,kka2_1:4_123,Kka2,kka2_1:4,P00552,,YES,123,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.888,-3.75,2.862,,0.007,H,A,0.55,-0.4,1.447,,48.86,BHB,-1.301,0.168804,0.00325188,0.385579 kka2_1:4_L123N,kka2_1:4_123,Kka2,kka2_1:4,P00552,,YES,123,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.888,-4.173,3.285,,0.007,H,A,0.55,-0.4,1.447,,48.86,BHB,-1.301,0.168804,0.00325188,0.380922 kka2_1:4_L123T,kka2_1:4_123,Kka2,kka2_1:4,P00552,,YES,123,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.888,-3.505,2.617,,0.007,H,A,0.55,-0.4,1.447,,48.86,BHB,-1.301,0.168804,0.00325188,0.454106 kka2_1:4_L123Y,kka2_1:4_123,Kka2,kka2_1:4,P00552,,YES,123,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.888,-4.021,3.133,,0.007,H,A,0.55,-0.4,1.447,,48.86,BHB,-1.301,0.168804,0.00325188,0.387363 kka2_1:4_L126C,kka2_1:4_126,Kka2,kka2_1:4,P00552,,YES,126,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.246,-4.83,3.584,,0.285,S,B,0.55,0.12,0.302,,51.89,PHA,-1.744,0.168804,0.0066485,0.563977 kka2_1:4_L126D,kka2_1:4_126,Kka2,kka2_1:4,P00552,,YES,126,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.246,-4.074,2.828,,0.285,S,B,0.55,0.12,0.302,,51.89,PHA,-1.744,0.168804,0.0066485,0.433283 kka2_1:4_L126K,kka2_1:4_126,Kka2,kka2_1:4,P00552,,YES,126,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.246,-3.81,2.564,,0.285,S,B,0.55,0.12,0.302,,51.89,PHA,-1.744,0.168804,0.0066485,0.440795 kka2_1:4_L126N,kka2_1:4_126,Kka2,kka2_1:4,P00552,,YES,126,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.246,-4.157,2.911,,0.285,S,B,0.55,0.12,0.302,,51.89,PHA,-1.744,0.168804,0.0066485,0.433635 kka2_1:4_L126T,kka2_1:4_126,Kka2,kka2_1:4,P00552,,YES,126,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.246,-2.585,1.339,,0.285,S,B,0.55,0.12,0.302,,51.89,PHA,-1.744,0.168804,0.0066485,0.529333 kka2_1:4_L126Y,kka2_1:4_126,Kka2,kka2_1:4,P00552,,YES,126,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.246,-4.126,2.88,,0.285,S,B,0.55,0.12,0.302,,51.89,PHA,-1.744,0.168804,0.0066485,0.459757 kka2_1:4_L152A,kka2_1:4_152,Kka2,kka2_1:4,P00552,,YES,152,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.521,-2.279,0.758,,0.547,,A,1.59,1.36,2.318,,63.64,OHH,-1.162,0.168804,0.00674868,0.692397 kka2_1:4_L152C,kka2_1:4_152,Kka2,kka2_1:4,P00552,,YES,152,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.521,-4.941,3.42,,0.547,,A,1.59,1.36,2.318,,63.64,OHH,-1.162,0.168804,0.00674868,0.643195 kka2_1:4_L152G,kka2_1:4_152,Kka2,kka2_1:4,P00552,,YES,152,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.521,-3.713,2.192,,0.547,,A,1.59,1.36,2.318,,63.64,OHH,-1.162,0.168804,0.00674868,0.635473 kka2_1:4_L152S,kka2_1:4_152,Kka2,kka2_1:4,P00552,,YES,152,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.521,-3.591,2.07,,0.547,,A,1.59,1.36,2.318,,63.64,OHH,-1.162,0.168804,0.00674868,0.649952 kka2_1:4_L152Y,kka2_1:4_152,Kka2,kka2_1:4,P00552,,YES,152,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.521,-4.238,2.717,,0.547,,A,1.59,1.36,2.318,,63.64,OHH,-1.162,0.168804,0.00674868,0.558954 kka2_1:4_L158C,kka2_1:4_158,Kka2,kka2_1:4,P00552,,YES,158,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.947,-4.909,2.962,,0.095,,B,1.59,0.77,7.588,,63.64,AHA,-1.25333,0.168804,0.00529068,0.652337 kka2_1:4_L158S,kka2_1:4_158,Kka2,kka2_1:4,P00552,,YES,158,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.947,-3.691,1.744,,0.095,,B,1.59,0.77,7.588,,63.64,AHA,-1.25333,0.168804,0.00529068,0.51178 kka2_1:4_L158T,kka2_1:4_158,Kka2,kka2_1:4,P00552,,YES,158,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.947,-3.635,1.688,,0.095,,B,1.59,0.77,7.588,,63.64,AHA,-1.25333,0.168804,0.00529068,0.510454 kka2_1:4_L165W,kka2_1:4_165,Kka2,kka2_1:4,P00552,,YES,165,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-2.453,-3.283,0.83,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.168804,0.00801161,0.780875 kka2_1:4_L170D,kka2_1:4_170,Kka2,kka2_1:4,P00552,,YES,170,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.28,-4.131,2.851,,0.029,H,A,0.55,0.11,1.851,,62.5,AHH,-1.534,0.168804,0.00730791,0.444709 kka2_1:4_L174W,kka2_1:4_174,Kka2,kka2_1:4,P00552,,YES,174,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.952,-5.22,4.268,,,H,A,0.55,-0.31,1.339,,51.89,BHB,-2.08533,0.168804,0.00438501,0.405954 kka2_1:4_L19A,kka2_1:4_19,Kka2,kka2_1:4,P00552,,YES,19,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.254,-3.301,2.047,,0.08,T,A,1.59,-0.26,2.645,,65.53,BHH,-2.221,0.168804,0.00620703,0.450752 kka2_1:4_L19D,kka2_1:4_19,Kka2,kka2_1:4,P00552,,YES,19,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.254,-4.151,2.897,,0.08,T,A,1.59,-0.26,2.645,,65.53,BHH,-2.221,0.168804,0.00620703,0.414479 kka2_1:4_L19E,kka2_1:4_19,Kka2,kka2_1:4,P00552,,YES,19,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.254,-3.966,2.712,,0.08,T,A,1.59,-0.26,2.645,,65.53,BHH,-2.221,0.168804,0.00620703,0.402117 kka2_1:4_L19Y,kka2_1:4_19,Kka2,kka2_1:4,P00552,,YES,19,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.254,-2.672,1.418,,0.08,T,A,1.59,-0.26,2.645,,65.53,BHH,-2.221,0.168804,0.00620703,0.543561 kka2_1:4_L212G,kka2_1:4_212,Kka2,kka2_1:4,P00552,,YES,212,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.904,-3.697,2.793,,,.,B,0.55,-0.78,0.23,,42.42,BHO,-0.799667,0.168804,0.0031426,0.479837 kka2_1:4_L223E,kka2_1:4_223,Kka2,kka2_1:4,P00552,,YES,223,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.861,-3.963,3.102,,,H,A,1.59,-1.24,1.268,,50,HHH,-0.854333,0.168804,0.00253574,0.380632 kka2_1:4_L241A,kka2_1:4_241,Kka2,kka2_1:4,P00552,,YES,241,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.158,-3.226,2.068,,0.08,H,A,0.55,-0.82,1.598,,63.26,HHH,-1.58533,0.168804,0.0117299,0.454828 kka2_1:4_L241S,kka2_1:4_241,Kka2,kka2_1:4,P00552,,YES,241,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.158,-3.689,2.531,,0.08,H,A,0.55,-0.82,1.598,,63.26,HHH,-1.58533,0.168804,0.0117299,0.464496 kka2_1:4_L243D,kka2_1:4_243,Kka2,kka2_1:4,P00552,,YES,243,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-2.651,-3.837,1.186,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.168804,0.00884927,0.541447 kka2_1:4_L243S,kka2_1:4_243,Kka2,kka2_1:4,P00552,,YES,243,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-2.651,-2.842,0.191,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.168804,0.00884927,0.699623 kka2_1:4_L260Y,kka2_1:4_260,Kka2,kka2_1:4,P00552,,YES,260,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.741,-3.966,3.225,,0.022,H,A,0.55,-0.52,,,,HHA,-0.845667,0.168804,0.0233782,0.365354 kka2_1:4_L39C,kka2_1:4_39,Kka2,kka2_1:4,P00552,,YES,39,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.223,-4.817,3.594,,,E,B,0.55,-1.21,1.998,,71.59,BHP,-1.69167,0.168804,0.00493618,0.537983 kka2_1:4_L39F,kka2_1:4_39,Kka2,kka2_1:4,P00552,,YES,39,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.223,-2.955,1.732,,,E,B,0.55,-1.21,1.998,,71.59,BHP,-1.69167,0.168804,0.00493618,0.503186 kka2_1:4_L39S,kka2_1:4_39,Kka2,kka2_1:4,P00552,,YES,39,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.223,-3.678,2.455,,,E,B,0.55,-1.21,1.998,,71.59,BHP,-1.69167,0.168804,0.00493618,0.460342 kka2_1:4_L39T,kka2_1:4_39,Kka2,kka2_1:4,P00552,,YES,39,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.223,-3.551,2.328,,,E,B,0.55,-1.21,1.998,,71.59,BHP,-1.69167,0.168804,0.00493618,0.496642 kka2_1:4_L39Y,kka2_1:4_39,Kka2,kka2_1:4,P00552,,YES,39,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.223,-4.042,2.819,,,E,B,0.55,-1.21,1.998,,71.59,BHP,-1.69167,0.168804,0.00493618,0.420314 kka2_1:4_L53A,kka2_1:4_53,Kka2,kka2_1:4,P00552,,YES,53,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-2.681,-2.486,-0.195,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.168804,0.00671168,0.875255 kka2_1:4_L53G,kka2_1:4_53,Kka2,kka2_1:4,P00552,,YES,53,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-2.681,-3.649,0.968,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.168804,0.00671168,0.775064 kka2_1:4_L53N,kka2_1:4_53,Kka2,kka2_1:4,P00552,,YES,53,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-2.681,-3.274,0.593,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.168804,0.00671168,0.809064 kka2_1:4_L53T,kka2_1:4_53,Kka2,kka2_1:4,P00552,,YES,53,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-2.681,-3.105,0.424,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.168804,0.00671168,0.778139 kka2_1:4_L53W,kka2_1:4_53,Kka2,kka2_1:4,P00552,,YES,53,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-2.681,-5.633,2.952,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.168804,0.00671168,0.86581 kka2_1:4_L57C,kka2_1:4_57,Kka2,kka2_1:4,P00552,,YES,57,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.898,-5.037,3.139,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.168804,0.00723769,0.597867 kka2_1:4_L57F,kka2_1:4_57,Kka2,kka2_1:4,P00552,,YES,57,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.898,-1.677,-0.221,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.168804,0.00723769,0.76753 kka2_1:4_L57G,kka2_1:4_57,Kka2,kka2_1:4,P00552,,YES,57,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.898,-3.786,1.888,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.168804,0.00723769,0.485808 kka2_1:4_L57S,kka2_1:4_57,Kka2,kka2_1:4,P00552,,YES,57,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.898,-3.77,1.872,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.168804,0.00723769,0.491058 kka2_1:4_L57Y,kka2_1:4_57,Kka2,kka2_1:4,P00552,,YES,57,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.898,-2.955,1.057,,0.343,T,A,1.59,0.98,5.438,,52.65,HHP,-2.20733,0.168804,0.00723769,0.57179 kka2_1:4_L60E,kka2_1:4_60,Kka2,kka2_1:4,P00552,,YES,60,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.997,-3.964,2.967,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.168804,0.00262176,0.455153 kka2_1:4_L60F,kka2_1:4_60,Kka2,kka2_1:4,P00552,,YES,60,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.997,-2.839,1.842,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.168804,0.00262176,0.518066 kka2_1:4_L60N,kka2_1:4_60,Kka2,kka2_1:4,P00552,,YES,60,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.997,-4.225,3.228,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.168804,0.00262176,0.434179 kka2_1:4_L60T,kka2_1:4_60,Kka2,kka2_1:4,P00552,,YES,60,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.997,-3.529,2.532,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.168804,0.00262176,0.48634 kka2_1:4_L60W,kka2_1:4_60,Kka2,kka2_1:4,P00552,,YES,60,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.997,-5.166,4.169,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.168804,0.00262176,0.412464 kka2_1:4_L60Y,kka2_1:4_60,Kka2,kka2_1:4,P00552,,YES,60,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.997,-3.955,2.958,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.168804,0.00262176,0.462418 kka2_1:4_L67C,kka2_1:4_67,Kka2,kka2_1:4,P00552,,YES,67,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.741,-4.665,3.924,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.168804,0.00102787,0.444752 kka2_1:4_L67E,kka2_1:4_67,Kka2,kka2_1:4,P00552,,YES,67,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.741,-3.918,3.177,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.168804,0.00102787,0.359357 kka2_1:4_L67G,kka2_1:4_67,Kka2,kka2_1:4,P00552,,YES,67,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.741,-3.836,3.095,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.168804,0.00102787,0.404758 kka2_1:4_L67H,kka2_1:4_67,Kka2,kka2_1:4,P00552,,YES,67,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.741,-4.933,4.192,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.168804,0.00102787,0.386242 kka2_1:4_L67I,kka2_1:4_67,Kka2,kka2_1:4,P00552,,YES,67,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.741,-2.914,2.173,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.168804,0.00102787,0.445205 kka2_1:4_L67K,kka2_1:4_67,Kka2,kka2_1:4,P00552,,YES,67,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.741,-3.71,2.969,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.168804,0.00102787,0.361813 kka2_1:4_L67N,kka2_1:4_67,Kka2,kka2_1:4,P00552,,YES,67,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.741,-4.151,3.41,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.168804,0.00102787,0.365438 kka2_1:4_L67Q,kka2_1:4_67,Kka2,kka2_1:4,P00552,,YES,67,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.741,-4.153,3.412,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.168804,0.00102787,0.371506 kka2_1:4_L67T,kka2_1:4_67,Kka2,kka2_1:4,P00552,,YES,67,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.741,-3.45,2.709,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.168804,0.00102787,0.41752 kka2_1:4_L70D,kka2_1:4_70,Kka2,kka2_1:4,P00552,,YES,70,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.017,-4.187,3.17,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.168804,0.00411884,0.404881 kka2_1:4_L70E,kka2_1:4_70,Kka2,kka2_1:4,P00552,,YES,70,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.017,-3.949,2.932,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.168804,0.00411884,0.395813 kka2_1:4_L70G,kka2_1:4_70,Kka2,kka2_1:4,P00552,,YES,70,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.017,-3.868,2.851,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.168804,0.00411884,0.444047 kka2_1:4_L70H,kka2_1:4_70,Kka2,kka2_1:4,P00552,,YES,70,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.017,-4.982,3.965,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.168804,0.00411884,0.415054 kka2_1:4_L70N,kka2_1:4_70,Kka2,kka2_1:4,P00552,,YES,70,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.017,-4.199,3.182,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.168804,0.00411884,0.394994 kka2_1:4_L70S,kka2_1:4_70,Kka2,kka2_1:4,P00552,,YES,70,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.017,-3.687,2.67,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.168804,0.00411884,0.445366 kka2_1:4_L70T,kka2_1:4_70,Kka2,kka2_1:4,P00552,,YES,70,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.017,-3.534,2.517,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.168804,0.00411884,0.453943 kka2_1:4_L70W,kka2_1:4_70,Kka2,kka2_1:4,P00552,,YES,70,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.017,-5.201,4.184,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.168804,0.00411884,0.390925 kka2_1:4_L70Y,kka2_1:4_70,Kka2,kka2_1:4,P00552,,YES,70,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.017,-4.068,3.051,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.168804,0.00411884,0.401877 kka2_1:4_L7E,kka2_1:4_7,Kka2,kka2_1:4,P00552,,YES,7,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.926,-3.32,1.394,,,,,,,3.012,,71.59,OHB,-2.12333,0.168804,0.00269456,0.990359 kka2_1:4_L7G,kka2_1:4_7,Kka2,kka2_1:4,P00552,,YES,7,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.926,-2.13,0.204,,,,,,,3.012,,71.59,OHB,-2.12333,0.168804,0.00269456,0.955638 kka2_1:4_L7T,kka2_1:4_7,Kka2,kka2_1:4,P00552,,YES,7,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.926,-3.425,1.499,,,,,,,3.012,,71.59,OHB,-2.12333,0.168804,0.00269456,1.00932 kka2_1:4_L81A,kka2_1:4_81,Kka2,kka2_1:4,P00552,,YES,81,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.427,-3.213,1.786,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.168804,0.00805839,0.550041 kka2_1:4_L81C,kka2_1:4_81,Kka2,kka2_1:4,P00552,,YES,81,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.427,-4.845,3.418,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.168804,0.00805839,0.72982 kka2_1:4_L81D,kka2_1:4_81,Kka2,kka2_1:4,P00552,,YES,81,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.427,-4.125,2.698,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.168804,0.00805839,0.622908 kka2_1:4_L81E,kka2_1:4_81,Kka2,kka2_1:4,P00552,,YES,81,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.427,-3.901,2.474,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.168804,0.00805839,0.623354 kka2_1:4_L81F,kka2_1:4_81,Kka2,kka2_1:4,P00552,,YES,81,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.427,-3.878,2.451,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.168804,0.00805839,0.628778 kka2_1:4_L81G,kka2_1:4_81,Kka2,kka2_1:4,P00552,,YES,81,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.427,-3.894,2.467,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.168804,0.00805839,0.650821 kka2_1:4_L81H,kka2_1:4_81,Kka2,kka2_1:4,P00552,,YES,81,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.427,-5.02,3.593,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.168804,0.00805839,0.65733 kka2_1:4_L81S,kka2_1:4_81,Kka2,kka2_1:4,P00552,,YES,81,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.427,-3.746,2.319,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.168804,0.00805839,0.650061 kka2_1:4_L81T,kka2_1:4_81,Kka2,kka2_1:4,P00552,,YES,81,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.427,-3.556,2.129,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.168804,0.00805839,0.651065 kka2_1:4_L81Y,kka2_1:4_81,Kka2,kka2_1:4,P00552,,YES,81,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.427,-4.125,2.698,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.168804,0.00805839,0.649035 kka2_1:4_L92A,kka2_1:4_92,Kka2,kka2_1:4,P00552,,YES,92,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.893,-3.128,2.235,,0.007,E,B,0.55,-0.19,1.447,,63.26,HHH,-0.962,0.168804,0.00307177,0.457588 kka2_1:4_L92C,kka2_1:4_92,Kka2,kka2_1:4,P00552,,YES,92,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.893,-4.72,3.827,,0.007,E,B,0.55,-0.19,1.447,,63.26,HHH,-0.962,0.168804,0.00307177,0.569253 kka2_1:4_L92D,kka2_1:4_92,Kka2,kka2_1:4,P00552,,YES,92,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.893,-4.173,3.28,,0.007,E,B,0.55,-0.19,1.447,,63.26,HHH,-0.962,0.168804,0.00307177,0.408258 kka2_1:4_L92G,kka2_1:4_92,Kka2,kka2_1:4,P00552,,YES,92,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.893,-3.838,2.945,,0.007,E,B,0.55,-0.19,1.447,,63.26,HHH,-0.962,0.168804,0.00307177,0.472526 kka2_1:4_L92I,kka2_1:4_92,Kka2,kka2_1:4,P00552,,YES,92,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.893,-2.953,2.06,,0.007,E,B,0.55,-0.19,1.447,,63.26,HHH,-0.962,0.168804,0.00307177,0.4688 kka2_1:4_L92K,kka2_1:4_92,Kka2,kka2_1:4,P00552,,YES,92,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.893,-3.743,2.85,,0.007,E,B,0.55,-0.19,1.447,,63.26,HHH,-0.962,0.168804,0.00307177,0.419799 kka2_1:4_L92N,kka2_1:4_92,Kka2,kka2_1:4,P00552,,YES,92,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.893,-4.184,3.291,,0.007,E,B,0.55,-0.19,1.447,,63.26,HHH,-0.962,0.168804,0.00307177,0.405228 kka2_1:4_L92S,kka2_1:4_92,Kka2,kka2_1:4,P00552,,YES,92,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.893,-3.672,2.779,,0.007,E,B,0.55,-0.19,1.447,,63.26,HHH,-0.962,0.168804,0.00307177,0.465124 kka2_1:4_L93C,kka2_1:4_93,Kka2,kka2_1:4,P00552,,YES,93,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.815,-4.726,3.911,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.168804,0.00131498,0.5622 kka2_1:4_L93D,kka2_1:4_93,Kka2,kka2_1:4,P00552,,YES,93,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.815,-4.139,3.324,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.168804,0.00131498,0.447201 kka2_1:4_L93E,kka2_1:4_93,Kka2,kka2_1:4,P00552,,YES,93,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.815,-3.848,3.033,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.168804,0.00131498,0.433661 kka2_1:4_L93G,kka2_1:4_93,Kka2,kka2_1:4,P00552,,YES,93,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.815,-3.804,2.989,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.168804,0.00131498,0.513284 kka2_1:4_L93K,kka2_1:4_93,Kka2,kka2_1:4,P00552,,YES,93,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.815,-3.596,2.781,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.168804,0.00131498,0.456413 kka2_1:4_L93N,kka2_1:4_93,Kka2,kka2_1:4,P00552,,YES,93,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.815,-4.082,3.267,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.168804,0.00131498,0.418188 kka2_1:4_L93S,kka2_1:4_93,Kka2,kka2_1:4,P00552,,YES,93,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.815,-3.637,2.822,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.168804,0.00131498,0.50708 kka2_1:4_L93T,kka2_1:4_93,Kka2,kka2_1:4,P00552,,YES,93,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.815,-3.473,2.658,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.168804,0.00131498,0.536099 kka2_1:4_L93W,kka2_1:4_93,Kka2,kka2_1:4,P00552,,YES,93,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.815,-5.169,4.354,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.168804,0.00131498,0.404146 kka2_1:4_L93Y,kka2_1:4_93,Kka2,kka2_1:4,P00552,,YES,93,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.815,-4.01,3.195,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.168804,0.00131498,0.435111 kka2_1:4_M120C,kka2_1:4_120,Kka2,kka2_1:4,P00552,,YES,120,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-3.877,-4.689,0.812,,,H,A,0.55,-0.42,2.259,,92.05,HHB,-2.16733,0.168804,0.00265808,0.599765 kka2_1:4_M120D,kka2_1:4_120,Kka2,kka2_1:4,P00552,,YES,120,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-3.877,-4.17,0.293,,,H,A,0.55,-0.42,2.259,,92.05,HHB,-2.16733,0.168804,0.00265808,0.504023 kka2_1:4_M120E,kka2_1:4_120,Kka2,kka2_1:4,P00552,,YES,120,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-3.877,-3.916,0.039,,,H,A,0.55,-0.42,2.259,,92.05,HHB,-2.16733,0.168804,0.00265808,0.487575 kka2_1:4_M120F,kka2_1:4_120,Kka2,kka2_1:4,P00552,,YES,120,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-3.877,-3.689,-0.188,,,H,A,0.55,-0.42,2.259,,92.05,HHB,-2.16733,0.168804,0.00265808,0.494347 kka2_1:4_M120G,kka2_1:4_120,Kka2,kka2_1:4,P00552,,YES,120,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-3.877,-3.835,-0.042,,,H,A,0.55,-0.42,2.259,,92.05,HHB,-2.16733,0.168804,0.00265808,0.455097 kka2_1:4_M120H,kka2_1:4_120,Kka2,kka2_1:4,P00552,,YES,120,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-3.877,-4.957,1.08,,,H,A,0.55,-0.42,2.259,,92.05,HHB,-2.16733,0.168804,0.00265808,0.620455 kka2_1:4_M120N,kka2_1:4_120,Kka2,kka2_1:4,P00552,,YES,120,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-3.877,-4.174,0.297,,,H,A,0.55,-0.42,2.259,,92.05,HHB,-2.16733,0.168804,0.00265808,0.516042 kka2_1:4_M120P,kka2_1:4_120,Kka2,kka2_1:4,P00552,,YES,120,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-3.877,-4.131,0.254,,,H,A,0.55,-0.42,2.259,,92.05,HHB,-2.16733,0.168804,0.00265808,0.448009 kka2_1:4_M120Q,kka2_1:4_120,Kka2,kka2_1:4,P00552,,YES,120,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-3.877,-4.176,0.299,,,H,A,0.55,-0.42,2.259,,92.05,HHB,-2.16733,0.168804,0.00265808,0.526536 kka2_1:4_M120R,kka2_1:4_120,Kka2,kka2_1:4,P00552,,YES,120,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-3.877,-4.005,0.128,,,H,A,0.55,-0.42,2.259,,92.05,HHB,-2.16733,0.168804,0.00265808,0.509099 kka2_1:4_M120Y,kka2_1:4_120,Kka2,kka2_1:4,P00552,,YES,120,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-3.877,-3.989,0.112,,,H,A,0.55,-0.42,2.259,,92.05,HHB,-2.16733,0.168804,0.00265808,0.503777 kka2_1:4_M148C,kka2_1:4_148,Kka2,kka2_1:4,P00552,,YES,148,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.847,-4.865,3.018,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.168804,0.00982664,0.574222 kka2_1:4_M148E,kka2_1:4_148,Kka2,kka2_1:4,P00552,,YES,148,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.847,-3.876,2.029,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.168804,0.00982664,0.448068 kka2_1:4_M148G,kka2_1:4_148,Kka2,kka2_1:4,P00552,,YES,148,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.847,-3.731,1.884,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.168804,0.00982664,0.450071 kka2_1:4_M148H,kka2_1:4_148,Kka2,kka2_1:4,P00552,,YES,148,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.847,-4.993,3.146,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.168804,0.00982664,0.496688 kka2_1:4_M148R,kka2_1:4_148,Kka2,kka2_1:4,P00552,,YES,148,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.847,-3.206,1.359,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.168804,0.00982664,0.513118 kka2_1:4_M178K,kka2_1:4_178,Kka2,kka2_1:4,P00552,,YES,178,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-3.206,-2.451,-0.755,,0.554,.,b,0.55,0.68,9.913,9.913,71.59,BHO,-2.154,0.168804,0.00717253,0.890132 kka2_1:4_M178N,kka2_1:4_178,Kka2,kka2_1:4,P00552,,YES,178,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-3.206,-3.899,0.693,,0.554,.,b,0.55,0.68,9.913,9.913,71.59,BHO,-2.154,0.168804,0.00717253,0.717038 kka2_1:4_M178P,kka2_1:4_178,Kka2,kka2_1:4,P00552,,YES,178,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-3.206,-3.217,0.011,,0.554,.,b,0.55,0.68,9.913,9.913,71.59,BHO,-2.154,0.168804,0.00717253,0.710215 kka2_1:4_M1A,kka2_1:4_1,Kka2,kka2_1:4,P00552,,YES,1,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.787,-2.808,1.021,,,,,,,1.347,,62.12,NAHH,-1.787,0.168804,0.00251939,0.830873 kka2_1:4_M1C,kka2_1:4_1,Kka2,kka2_1:4,P00552,,YES,1,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.787,-4.448,2.661,,,,,,,1.347,,62.12,NAHH,-1.787,0.168804,0.00251939,0.882897 kka2_1:4_M1D,kka2_1:4_1,Kka2,kka2_1:4,P00552,,YES,1,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.787,-3.73,1.943,,,,,,,1.347,,62.12,NAHH,-1.787,0.168804,0.00251939,0.842756 kka2_1:4_M1E,kka2_1:4_1,Kka2,kka2_1:4,P00552,,YES,1,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.787,-3.476,1.689,,,,,,,1.347,,62.12,NAHH,-1.787,0.168804,0.00251939,0.809504 kka2_1:4_M1F,kka2_1:4_1,Kka2,kka2_1:4,P00552,,YES,1,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.787,-3.498,1.711,,,,,,,1.347,,62.12,NAHH,-1.787,0.168804,0.00251939,0.820439 kka2_1:4_M1G,kka2_1:4_1,Kka2,kka2_1:4,P00552,,YES,1,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.787,-3.394,1.607,,,,,,,1.347,,62.12,NAHH,-1.787,0.168804,0.00251939,0.815781 kka2_1:4_M1H,kka2_1:4_1,Kka2,kka2_1:4,P00552,,YES,1,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.787,-4.561,2.774,,,,,,,1.347,,62.12,NAHH,-1.787,0.168804,0.00251939,0.861737 kka2_1:4_M1K,kka2_1:4_1,Kka2,kka2_1:4,P00552,,YES,1,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.787,-3.337,1.55,,,,,,,1.347,,62.12,NAHH,-1.787,0.168804,0.00251939,0.818238 kka2_1:4_M1N,kka2_1:4_1,Kka2,kka2_1:4,P00552,,YES,1,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.787,-3.778,1.991,,,,,,,1.347,,62.12,NAHH,-1.787,0.168804,0.00251939,0.858469 kka2_1:4_M1P,kka2_1:4_1,Kka2,kka2_1:4,P00552,,YES,1,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.787,-3.691,1.904,,,,,,,1.347,,62.12,NAHH,-1.787,0.168804,0.00251939,0.831311 kka2_1:4_M1Q,kka2_1:4_1,Kka2,kka2_1:4,P00552,,YES,1,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.787,-3.614,1.827,,,,,,,1.347,,62.12,NAHH,-1.787,0.168804,0.00251939,0.830038 kka2_1:4_M1S,kka2_1:4_1,Kka2,kka2_1:4,P00552,,YES,1,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.787,-3.266,1.479,,,,,,,1.347,,62.12,NAHH,-1.787,0.168804,0.00251939,0.79871 kka2_1:4_M1W,kka2_1:4_1,Kka2,kka2_1:4,P00552,,YES,1,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.787,-4.812,3.025,,,,,,,1.347,,62.12,NAHH,-1.787,0.168804,0.00251939,0.854539 kka2_1:4_M1Y,kka2_1:4_1,Kka2,kka2_1:4,P00552,,YES,1,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.787,-3.748,1.961,,,,,,,1.347,,62.12,NAHH,-1.787,0.168804,0.00251939,0.853283 kka2_1:4_N58A,kka2_1:4_58,Kka2,kka2_1:4,P00552,,YES,58,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-2.641,-1.819,-0.822,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.168804,0.00793425,0.80356 kka2_1:4_N58F,kka2_1:4_58,Kka2,kka2_1:4,P00552,,YES,58,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-2.641,-4.413,1.772,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.168804,0.00793425,0.555854 kka2_1:4_N58G,kka2_1:4_58,Kka2,kka2_1:4,P00552,,YES,58,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-2.641,-1.779,-0.862,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.168804,0.00793425,0.789586 kka2_1:4_N58H,kka2_1:4_58,Kka2,kka2_1:4,P00552,,YES,58,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-2.641,-4.779,2.138,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.168804,0.00793425,0.677682 kka2_1:4_N58I,kka2_1:4_58,Kka2,kka2_1:4,P00552,,YES,58,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-2.641,-4.075,1.434,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.168804,0.00793425,0.55171 kka2_1:4_N58L,kka2_1:4_58,Kka2,kka2_1:4,P00552,,YES,58,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-2.641,-3.653,1.012,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.168804,0.00793425,0.538325 kka2_1:4_N58M,kka2_1:4_58,Kka2,kka2_1:4,P00552,,YES,58,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-2.641,-4.871,2.23,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.168804,0.00793425,0.673184 kka2_1:4_N58P,kka2_1:4_58,Kka2,kka2_1:4,P00552,,YES,58,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-2.641,-4.016,1.375,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.168804,0.00793425,0.474392 kka2_1:4_N58Q,kka2_1:4_58,Kka2,kka2_1:4,P00552,,YES,58,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-2.641,-4.107,1.466,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.168804,0.00793425,0.57622 kka2_1:4_N58R,kka2_1:4_58,Kka2,kka2_1:4,P00552,,YES,58,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-2.641,-3.198,0.557,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.168804,0.00793425,0.63921 kka2_1:4_N58V,kka2_1:4_58,Kka2,kka2_1:4,P00552,,YES,58,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-2.641,-3.703,1.062,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.168804,0.00793425,0.540563 kka2_1:4_N58W,kka2_1:4_58,Kka2,kka2_1:4,P00552,,YES,58,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-2.641,-5.525,2.884,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.168804,0.00793425,0.696479 kka2_1:4_P109E,kka2_1:4_109,Kka2,kka2_1:4,P00552,,YES,109,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.412,-2.892,1.48,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.168804,0.0070929,0.499472 kka2_1:4_P109G,kka2_1:4_109,Kka2,kka2_1:4,P00552,,YES,109,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.412,-3.439,2.027,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.168804,0.0070929,0.518799 kka2_1:4_P109W,kka2_1:4_109,Kka2,kka2_1:4,P00552,,YES,109,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.412,-3.457,2.045,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.168804,0.0070929,0.49252 kka2_1:4_P128D,kka2_1:4_128,Kka2,kka2_1:4,P00552,,YES,128,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.922,-4.006,2.084,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.168804,0.00774689,0.41293 kka2_1:4_P128G,kka2_1:4_128,Kka2,kka2_1:4,P00552,,YES,128,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.922,-3.745,1.823,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.168804,0.00774689,0.420782 kka2_1:4_P128K,kka2_1:4_128,Kka2,kka2_1:4,P00552,,YES,128,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.922,-3.891,1.969,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.168804,0.00774689,0.417843 kka2_1:4_P128N,kka2_1:4_128,Kka2,kka2_1:4,P00552,,YES,128,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.922,-4.215,2.293,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.168804,0.00774689,0.45231 kka2_1:4_P128Y,kka2_1:4_128,Kka2,kka2_1:4,P00552,,YES,128,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.922,-3.242,1.32,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.168804,0.00774689,0.48596 kka2_1:4_P12N,kka2_1:4_12,Kka2,kka2_1:4,P00552,,YES,12,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.853,-3.936,3.083,,,,B,0.52,1.25,0.843,,48.11,POH,-1.80767,0.168804,0.00500011,0.457439 kka2_1:4_P132C,kka2_1:4_132,Kka2,kka2_1:4,P00552,,YES,132,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.775,-5.083,4.308,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.168804,0.0018489,0.552508 kka2_1:4_P132E,kka2_1:4_132,Kka2,kka2_1:4,P00552,,YES,132,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.775,-3.466,2.691,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.168804,0.0018489,0.45921 kka2_1:4_P132F,kka2_1:4_132,Kka2,kka2_1:4,P00552,,YES,132,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.775,-4.513,3.738,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.168804,0.0018489,0.487946 kka2_1:4_P132N,kka2_1:4_132,Kka2,kka2_1:4,P00552,,YES,132,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.775,-3.857,3.082,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.168804,0.0018489,0.492266 kka2_1:4_P132Y,kka2_1:4_132,Kka2,kka2_1:4,P00552,,YES,132,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.775,-4.414,3.639,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.168804,0.0018489,0.480126 kka2_1:4_P167C,kka2_1:4_167,Kka2,kka2_1:4,P00552,,YES,167,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-2.403,-4.818,2.415,,0.18,H,A,0.52,0.75,3.6,,64.39,HOH,-2.26633,0.168804,0.00543203,0.705058 kka2_1:4_P167F,kka2_1:4_167,Kka2,kka2_1:4,P00552,,YES,167,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-2.403,-4.229,1.826,,0.18,H,A,0.52,0.75,3.6,,64.39,HOH,-2.26633,0.168804,0.00543203,0.559367 kka2_1:4_P167Y,kka2_1:4_167,Kka2,kka2_1:4,P00552,,YES,167,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-2.403,-4.35,1.947,,0.18,H,A,0.52,0.75,3.6,,64.39,HOH,-2.26633,0.168804,0.00543203,0.606293 kka2_1:4_P249C,kka2_1:4_249,Kka2,kka2_1:4,P00552,,YES,249,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.867,-5.002,3.135,,0.406,.,B,0.52,-0.01,,,92.05,HOA,-1.66867,0.168804,0.011045,0.799177 kka2_1:4_P249D,kka2_1:4_249,Kka2,kka2_1:4,P00552,,YES,249,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.867,-3.169,1.302,,0.406,.,B,0.52,-0.01,,,92.05,HOA,-1.66867,0.168804,0.011045,0.686321 kka2_1:4_P249G,kka2_1:4_249,Kka2,kka2_1:4,P00552,,YES,249,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.867,-3.661,1.794,,0.406,.,B,0.52,-0.01,,,92.05,HOA,-1.66867,0.168804,0.011045,0.719454 kka2_1:4_P249N,kka2_1:4_249,Kka2,kka2_1:4,P00552,,YES,249,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.867,-4.142,2.275,,0.406,.,B,0.52,-0.01,,,92.05,HOA,-1.66867,0.168804,0.011045,0.788458 kka2_1:4_P249Y,kka2_1:4_249,Kka2,kka2_1:4,P00552,,YES,249,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.867,-4.279,2.412,,0.406,.,B,0.52,-0.01,,,92.05,HOA,-1.66867,0.168804,0.011045,0.789152 kka2_1:4_P98I,kka2_1:4_98,Kka2,kka2_1:4,P00552,,YES,98,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.526,-4.079,2.553,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.168804,0.00622754,0.45652 kka2_1:4_P98W,kka2_1:4_98,Kka2,kka2_1:4,P00552,,YES,98,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.526,-5.629,4.103,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.168804,0.00622754,0.489058 kka2_1:4_Q100F,kka2_1:4_100,Kka2,kka2_1:4,P00552,,YES,100,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.77,-4.378,1.608,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.168804,0.0066405,0.646986 kka2_1:4_Q155C,kka2_1:4_155,Kka2,kka2_1:4,P00552,,YES,155,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.606,-5.171,2.565,,0.525,T,A,0.64,1.49,1.592,,63.64,APA,-1.726,0.168804,0.00641853,0.872562 kka2_1:4_Q155I,kka2_1:4_155,Kka2,kka2_1:4,P00552,,YES,155,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.606,-3.926,1.32,,0.525,T,A,0.64,1.49,1.592,,63.64,APA,-1.726,0.168804,0.00641853,0.743275 kka2_1:4_Q155T,kka2_1:4_155,Kka2,kka2_1:4,P00552,,YES,155,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.606,-3.529,0.923,,0.525,T,A,0.64,1.49,1.592,,63.64,APA,-1.726,0.168804,0.00641853,0.828775 kka2_1:4_Q163S,kka2_1:4_163,Kka2,kka2_1:4,P00552,,YES,163,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.162,-3.535,1.373,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.168804,0.00719507,0.760358 kka2_1:4_Q252I,kka2_1:4_252,Kka2,kka2_1:4,P00552,,YES,252,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.63,-4.083,1.453,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.168804,0.0121001,0.851849 kka2_1:4_Q252S,kka2_1:4_252,Kka2,kka2_1:4,P00552,,YES,252,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.63,-2.755,0.125,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.168804,0.0121001,0.922954 kka2_1:4_Q26I,kka2_1:4_26,Kka2,kka2_1:4,P00552,,YES,26,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.18,-4.055,1.875,,0.448,E,B,0.4,0.44,5.022,,92.05,HPP,-2.11167,0.168804,0.00708962,0.753727 kka2_1:4_Q26S,kka2_1:4_26,Kka2,kka2_1:4,P00552,,YES,26,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.18,-3.511,1.331,,0.448,E,B,0.4,0.44,5.022,,92.05,HPP,-2.11167,0.168804,0.00708962,0.756832 kka2_1:4_Q27C,kka2_1:4_27,Kka2,kka2_1:4,P00552,,YES,27,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-1.659,-5.15,3.491,,0.608,,A,0.4,0.71,1.498,,65.53,PPP,-1.90733,0.168804,0.00595365,0.73089 kka2_1:4_Q27G,kka2_1:4_27,Kka2,kka2_1:4,P00552,,YES,27,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-1.659,-3.564,1.905,,0.608,,A,0.4,0.71,1.498,,65.53,PPP,-1.90733,0.168804,0.00595365,0.682435 kka2_1:4_Q27V,kka2_1:4_27,Kka2,kka2_1:4,P00552,,YES,27,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-1.659,-2.648,0.989,,0.608,,A,0.4,0.71,1.498,,65.53,PPP,-1.90733,0.168804,0.00595365,0.708748 kka2_1:4_Q42A,kka2_1:4_42,Kka2,kka2_1:4,P00552,,YES,42,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.907,-2.221,-0.686,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.168804,0.00679212,1.03517 kka2_1:4_Q42D,kka2_1:4_42,Kka2,kka2_1:4,P00552,,YES,42,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.907,-2.294,-0.613,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.168804,0.00679212,1.02559 kka2_1:4_Q42F,kka2_1:4_42,Kka2,kka2_1:4,P00552,,YES,42,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.907,-4.511,1.604,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.168804,0.00679212,0.789889 kka2_1:4_Q42V,kka2_1:4_42,Kka2,kka2_1:4,P00552,,YES,42,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.907,-3.778,0.871,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.168804,0.00679212,0.798261 kka2_1:4_Q42W,kka2_1:4_42,Kka2,kka2_1:4,P00552,,YES,42,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.907,-5.634,2.727,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.168804,0.00679212,0.762662 kka2_1:4_Q4G,kka2_1:4_4,Kka2,kka2_1:4,P00552,,YES,4,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.361,-1.897,-0.464,,,,,,,2.026,,71.59,APA,-1.95533,0.168804,0.00239179,1.04049 kka2_1:4_Q61I,kka2_1:4_61,Kka2,kka2_1:4,P00552,,YES,61,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.982,-3.937,0.955,,0.591,H,A,0.64,0.41,3.484,,65.53,HPA,-1.85667,0.168804,0.00612092,0.722394 kka2_1:4_Q61M,kka2_1:4_61,Kka2,kka2_1:4,P00552,,YES,61,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.982,-4.764,1.782,,0.591,H,A,0.64,0.41,3.484,,65.53,HPA,-1.85667,0.168804,0.00612092,0.766986 kka2_1:4_Q61N,kka2_1:4_61,Kka2,kka2_1:4,P00552,,YES,61,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.982,-3.133,0.151,,0.591,H,A,0.64,0.41,3.484,,65.53,HPA,-1.85667,0.168804,0.00612092,0.821816 kka2_1:4_Q61T,kka2_1:4_61,Kka2,kka2_1:4,P00552,,YES,61,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.982,-2.975,-0.007,,0.591,H,A,0.64,0.41,3.484,,65.53,HPA,-1.85667,0.168804,0.00612092,0.824565 kka2_1:4_Q61V,kka2_1:4_61,Kka2,kka2_1:4,P00552,,YES,61,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.982,-2.81,-0.172,,0.591,H,A,0.64,0.41,3.484,,65.53,HPA,-1.85667,0.168804,0.00612092,0.846287 kka2_1:4_Q61Y,kka2_1:4_61,Kka2,kka2_1:4,P00552,,YES,61,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.982,-4.455,1.473,,0.591,H,A,0.64,0.41,3.484,,65.53,HPA,-1.85667,0.168804,0.00612092,0.767139 kka2_1:4_R121A,kka2_1:4_121,Kka2,kka2_1:4,P00552,,YES,121,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.552,-2.713,1.161,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.168804,0.00523326,0.636479 kka2_1:4_R121E,kka2_1:4_121,Kka2,kka2_1:4,P00552,,YES,121,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.552,-2.795,1.243,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.168804,0.00523326,0.616769 kka2_1:4_R121F,kka2_1:4_121,Kka2,kka2_1:4,P00552,,YES,121,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.552,-4.32,2.768,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.168804,0.00523326,0.570472 kka2_1:4_R121I,kka2_1:4_121,Kka2,kka2_1:4,P00552,,YES,121,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.552,-3.978,2.426,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.168804,0.00523326,0.531623 kka2_1:4_R121K,kka2_1:4_121,Kka2,kka2_1:4,P00552,,YES,121,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.552,-2.242,0.69,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.168804,0.00523326,0.709263 kka2_1:4_R121M,kka2_1:4_121,Kka2,kka2_1:4,P00552,,YES,121,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.552,-4.593,3.041,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.168804,0.00523326,0.590629 kka2_1:4_R121N,kka2_1:4_121,Kka2,kka2_1:4,P00552,,YES,121,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.552,-3.678,2.126,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.168804,0.00523326,0.599923 kka2_1:4_R121T,kka2_1:4_121,Kka2,kka2_1:4,P00552,,YES,121,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.552,-3.59,2.038,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.168804,0.00523326,0.618852 kka2_1:4_R121V,kka2_1:4_121,Kka2,kka2_1:4,P00552,,YES,121,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.552,-3.699,2.147,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.168804,0.00523326,0.608442 kka2_1:4_R121Y,kka2_1:4_121,Kka2,kka2_1:4,P00552,,YES,121,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.552,-4.18,2.628,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.168804,0.00523326,0.571379 kka2_1:4_R122A,kka2_1:4_122,Kka2,kka2_1:4,P00552,,YES,122,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.175,-2.209,0.034,,0.487,H,A,0.16,0.26,16.436,16.436,71.59,BBH,-1.53833,0.168804,0.00736512,0.890896 kka2_1:4_R122E,kka2_1:4_122,Kka2,kka2_1:4,P00552,,YES,122,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.175,-2.696,0.521,,0.487,H,A,0.16,0.26,16.436,16.436,71.59,BBH,-1.53833,0.168804,0.00736512,0.798183 kka2_1:4_R122F,kka2_1:4_122,Kka2,kka2_1:4,P00552,,YES,122,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.175,-4.454,2.279,,0.487,H,A,0.16,0.26,16.436,16.436,71.59,BBH,-1.53833,0.168804,0.00736512,0.800569 kka2_1:4_R122I,kka2_1:4_122,Kka2,kka2_1:4,P00552,,YES,122,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.175,-4.03,1.855,,0.487,H,A,0.16,0.26,16.436,16.436,71.59,BBH,-1.53833,0.168804,0.00736512,0.743517 kka2_1:4_R122K,kka2_1:4_122,Kka2,kka2_1:4,P00552,,YES,122,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.175,-3.561,1.386,,0.487,H,A,0.16,0.26,16.436,16.436,71.59,BBH,-1.53833,0.168804,0.00736512,0.730232 kka2_1:4_R122M,kka2_1:4_122,Kka2,kka2_1:4,P00552,,YES,122,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.175,-3.353,1.178,,0.487,H,A,0.16,0.26,16.436,16.436,71.59,BBH,-1.53833,0.168804,0.00736512,0.724834 kka2_1:4_R122V,kka2_1:4_122,Kka2,kka2_1:4,P00552,,YES,122,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.175,-2.949,0.774,,0.487,H,A,0.16,0.26,16.436,16.436,71.59,BBH,-1.53833,0.168804,0.00736512,0.787703 kka2_1:4_R122Y,kka2_1:4_122,Kka2,kka2_1:4,P00552,,YES,122,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.175,-4.411,2.236,,0.487,H,A,0.16,0.26,16.436,16.436,71.59,BBH,-1.53833,0.168804,0.00736512,0.796717 kka2_1:4_R140I,kka2_1:4_140,Kka2,kka2_1:4,P00552,,YES,140,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.351,-4.1,2.749,,0.12,H,A,1.2,0.2,2.561,,53.03,BBH,-1.885,0.168804,0.00430167,0.412271 kka2_1:4_R143M,kka2_1:4_143,Kka2,kka2_1:4,P00552,,YES,143,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.525,-4.625,2.1,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.168804,0.00662247,0.76136 kka2_1:4_R143W,kka2_1:4_143,Kka2,kka2_1:4,P00552,,YES,143,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.525,-5.57,3.045,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.168804,0.00662247,0.760941 kka2_1:4_R145D,kka2_1:4_145,Kka2,kka2_1:4,P00552,,YES,145,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.804,-3.693,1.889,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.168804,0.00846663,0.613839 kka2_1:4_R145F,kka2_1:4_145,Kka2,kka2_1:4,P00552,,YES,145,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.804,-4.396,2.592,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.168804,0.00846663,0.644679 kka2_1:4_R145V,kka2_1:4_145,Kka2,kka2_1:4,P00552,,YES,145,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.804,-3.111,1.307,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.168804,0.00846663,0.650177 kka2_1:4_R145Y,kka2_1:4_145,Kka2,kka2_1:4,P00552,,YES,145,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.804,-4.267,2.463,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.168804,0.00846663,0.600982 kka2_1:4_R147A,kka2_1:4_147,Kka2,kka2_1:4,P00552,,YES,147,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.123,-3.267,2.144,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.168804,0.00549168,0.558678 kka2_1:4_R147D,kka2_1:4_147,Kka2,kka2_1:4,P00552,,YES,147,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.123,-3.649,2.526,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.168804,0.00549168,0.503159 kka2_1:4_R147E,kka2_1:4_147,Kka2,kka2_1:4,P00552,,YES,147,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.123,-3.304,2.181,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.168804,0.00549168,0.548708 kka2_1:4_R147M,kka2_1:4_147,Kka2,kka2_1:4,P00552,,YES,147,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.123,-4.65,3.527,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.168804,0.00549168,0.513103 kka2_1:4_R147Y,kka2_1:4_147,Kka2,kka2_1:4,P00552,,YES,147,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.123,-4.044,2.921,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.168804,0.00549168,0.478968 kka2_1:4_R18A,kka2_1:4_18,Kka2,kka2_1:4,P00552,,YES,18,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.055,-2.49,0.435,,0.474,T,A,1.2,0.54,8.405,8.405,71.59,ABH,-1.821,0.168804,0.00724065,0.849682 kka2_1:4_R18D,kka2_1:4_18,Kka2,kka2_1:4,P00552,,YES,18,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.055,-2.8,0.745,,0.474,T,A,1.2,0.54,8.405,8.405,71.59,ABH,-1.821,0.168804,0.00724065,0.81047 kka2_1:4_R18K,kka2_1:4_18,Kka2,kka2_1:4,P00552,,YES,18,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.055,-2.865,0.81,,0.474,T,A,1.2,0.54,8.405,8.405,71.59,ABH,-1.821,0.168804,0.00724065,0.881563 kka2_1:4_R202K,kka2_1:4_202,Kka2,kka2_1:4,P00552,,YES,202,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.761,-2.914,1.153,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.168804,0.00696498,0.662822 kka2_1:4_R202Y,kka2_1:4_202,Kka2,kka2_1:4,P00552,,YES,202,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.761,-4.316,2.555,,0.607,E,B,1.2,0.48,0.347,,52.27,OBH,-1.41067,0.168804,0.00696498,0.515438 kka2_1:4_R211I,kka2_1:4_211,Kka2,kka2_1:4,P00552,,YES,211,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-0.899,-4.062,3.163,,0.12,T,a,1.2,-0.39,1.088,,49.62,OBH,-0.966,0.168804,0.00204888,0.423273 kka2_1:4_R239M,kka2_1:4_239,Kka2,kka2_1:4,P00552,,YES,239,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.949,-4.723,1.774,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.168804,0.00835326,0.729233 kka2_1:4_R38A,kka2_1:4_38,Kka2,kka2_1:4,P00552,,YES,38,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.207,-3.17,1.963,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.168804,0.00372499,0.549466 kka2_1:4_R44N,kka2_1:4_44,Kka2,kka2_1:4,P00552,,YES,44,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.062,-3.108,1.046,,0.487,S,B,1.2,-0.35,5.71,,71.59,OBO,-1.80767,0.168804,0.00745043,0.660785 kka2_1:4_R44Y,kka2_1:4_44,Kka2,kka2_1:4,P00552,,YES,44,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.062,-4.366,2.304,,0.487,S,B,1.2,-0.35,5.71,,71.59,OBO,-1.80767,0.168804,0.00745043,0.684553 kka2_1:4_R66D,kka2_1:4_66,Kka2,kka2_1:4,P00552,,YES,66,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-0.922,-3.72,2.798,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.168804,0.00161025,0.410117 kka2_1:4_R66F,kka2_1:4_66,Kka2,kka2_1:4,P00552,,YES,66,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-0.922,-4.355,3.433,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.168804,0.00161025,0.411499 kka2_1:4_R66G,kka2_1:4_66,Kka2,kka2_1:4,P00552,,YES,66,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-0.922,-3.421,2.499,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.168804,0.00161025,0.487048 kka2_1:4_R66I,kka2_1:4_66,Kka2,kka2_1:4,P00552,,YES,66,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-0.922,-4.073,3.151,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.168804,0.00161025,0.400656 kka2_1:4_R66M,kka2_1:4_66,Kka2,kka2_1:4,P00552,,YES,66,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-0.922,-4.542,3.62,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.168804,0.00161025,0.424351 kka2_1:4_R66N,kka2_1:4_66,Kka2,kka2_1:4,P00552,,YES,66,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-0.922,-3.51,2.588,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.168804,0.00161025,0.406118 kka2_1:4_R66P,kka2_1:4_66,Kka2,kka2_1:4,P00552,,YES,66,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-0.922,-3.906,2.984,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.168804,0.00161025,0.467421 kka2_1:4_R89A,kka2_1:4_89,Kka2,kka2_1:4,P00552,,YES,89,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.548,-2.806,1.258,,0.209,E,B,1.2,1.41,4.412,,64.39,OBA,-1.89867,0.168804,0.00524373,0.605931 kka2_1:4_R89D,kka2_1:4_89,Kka2,kka2_1:4,P00552,,YES,89,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.548,-3.735,2.187,,0.209,E,B,1.2,1.41,4.412,,64.39,OBA,-1.89867,0.168804,0.00524373,0.525832 kka2_1:4_R89E,kka2_1:4_89,Kka2,kka2_1:4,P00552,,YES,89,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.548,-2.88,1.332,,0.209,E,B,1.2,1.41,4.412,,64.39,OBA,-1.89867,0.168804,0.00524373,0.575592 kka2_1:4_R89F,kka2_1:4_89,Kka2,kka2_1:4,P00552,,YES,89,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.548,-3.236,1.688,,0.209,E,B,1.2,1.41,4.412,,64.39,OBA,-1.89867,0.168804,0.00524373,0.565898 kka2_1:4_R89I,kka2_1:4_89,Kka2,kka2_1:4,P00552,,YES,89,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.548,-4.125,2.577,,0.209,E,B,1.2,1.41,4.412,,64.39,OBA,-1.89867,0.168804,0.00524373,0.485868 kka2_1:4_R89K,kka2_1:4_89,Kka2,kka2_1:4,P00552,,YES,89,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.548,-2.811,1.263,,0.209,E,B,1.2,1.41,4.412,,64.39,OBA,-1.89867,0.168804,0.00524373,0.621536 kka2_1:4_R89M,kka2_1:4_89,Kka2,kka2_1:4,P00552,,YES,89,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.548,-4.745,3.197,,0.209,E,B,1.2,1.41,4.412,,64.39,OBA,-1.89867,0.168804,0.00524373,0.551203 kka2_1:4_R89P,kka2_1:4_89,Kka2,kka2_1:4,P00552,,YES,89,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.548,-4.076,2.528,,0.209,E,B,1.2,1.41,4.412,,64.39,OBA,-1.89867,0.168804,0.00524373,0.534113 kka2_1:4_R89Q,kka2_1:4_89,Kka2,kka2_1:4,P00552,,YES,89,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.548,-2.675,1.127,,0.209,E,B,1.2,1.41,4.412,,64.39,OBA,-1.89867,0.168804,0.00524373,0.643864 kka2_1:4_R89T,kka2_1:4_89,Kka2,kka2_1:4,P00552,,YES,89,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.548,-2.992,1.444,,0.209,E,B,1.2,1.41,4.412,,64.39,OBA,-1.89867,0.168804,0.00524373,0.591289 kka2_1:4_R89V,kka2_1:4_89,Kka2,kka2_1:4,P00552,,YES,89,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.548,-3.804,2.256,,0.209,E,B,1.2,1.41,4.412,,64.39,OBA,-1.89867,0.168804,0.00524373,0.576246 kka2_1:4_R89W,kka2_1:4_89,Kka2,kka2_1:4,P00552,,YES,89,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.548,-5.305,3.757,,0.209,E,B,1.2,1.41,4.412,,64.39,OBA,-1.89867,0.168804,0.00524373,0.551955 kka2_1:4_R89Y,kka2_1:4_89,Kka2,kka2_1:4,P00552,,YES,89,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.548,-2.904,1.356,,0.209,E,B,1.2,1.41,4.412,,64.39,OBA,-1.89867,0.168804,0.00524373,0.608785 kka2_1:4_S104F,kka2_1:4_104,Kka2,kka2_1:4,P00552,,YES,104,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.436,-4.301,2.865,,0.536,T,A,0.27,-1.11,0.357,,63.64,HPP,-1.91433,0.168804,0.00555207,0.486297 kka2_1:4_S104H,kka2_1:4_104,Kka2,kka2_1:4,P00552,,YES,104,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.436,-3.319,1.883,,0.536,T,A,0.27,-1.11,0.357,,63.64,HPP,-1.91433,0.168804,0.00555207,0.516442 kka2_1:4_S104M,kka2_1:4_104,Kka2,kka2_1:4,P00552,,YES,104,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.436,-4.687,3.251,,0.536,T,A,0.27,-1.11,0.357,,63.64,HPP,-1.91433,0.168804,0.00555207,0.526127 kka2_1:4_S105D,kka2_1:4_105,Kka2,kka2_1:4,P00552,,YES,105,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.945,-2.638,0.693,,0.056,S,B,0.77,-1.04,3.442,,65.53,PPB,-2.17033,0.168804,0.00847233,0.52968 kka2_1:4_S105V,kka2_1:4_105,Kka2,kka2_1:4,P00552,,YES,105,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.945,-2.997,1.052,,0.056,S,B,0.77,-1.04,3.442,,65.53,PPB,-2.17033,0.168804,0.00847233,0.460675 kka2_1:4_S105W,kka2_1:4_105,Kka2,kka2_1:4,P00552,,YES,105,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.945,-5.544,3.599,,0.056,S,B,0.77,-1.04,3.442,,65.53,PPB,-2.17033,0.168804,0.00847233,0.472867 kka2_1:4_S105Y,kka2_1:4_105,Kka2,kka2_1:4,P00552,,YES,105,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.945,-4.433,2.488,,0.056,S,B,0.77,-1.04,3.442,,65.53,PPB,-2.17033,0.168804,0.00847233,0.487981 kka2_1:4_S114A,kka2_1:4_114,Kka2,kka2_1:4,P00552,,YES,114,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.527,-2.102,-0.425,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.168804,0.00705262,1.03533 kka2_1:4_S114P,kka2_1:4_114,Kka2,kka2_1:4,P00552,,YES,114,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.527,-4.051,1.524,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.168804,0.00705262,0.600639 kka2_1:4_S114V,kka2_1:4_114,Kka2,kka2_1:4,P00552,,YES,114,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.527,-2.736,0.209,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.168804,0.00705262,0.840626 kka2_1:4_S114Y,kka2_1:4_114,Kka2,kka2_1:4,P00552,,YES,114,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.527,-4.358,1.831,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.168804,0.00705262,0.74107 kka2_1:4_S11D,kka2_1:4_11,Kka2,kka2_1:4,P00552,,YES,11,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.322,-3.766,1.444,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.168804,0.00381691,0.791392 kka2_1:4_S11E,kka2_1:4_11,Kka2,kka2_1:4,P00552,,YES,11,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.322,-3.629,1.307,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.168804,0.00381691,0.815689 kka2_1:4_S11F,kka2_1:4_11,Kka2,kka2_1:4,P00552,,YES,11,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.322,-3.896,1.574,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.168804,0.00381691,0.821959 kka2_1:4_S11H,kka2_1:4_11,Kka2,kka2_1:4,P00552,,YES,11,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.322,-4.78,2.458,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.168804,0.00381691,0.812924 kka2_1:4_S11K,kka2_1:4_11,Kka2,kka2_1:4,P00552,,YES,11,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.322,-3.575,1.253,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.168804,0.00381691,0.852624 kka2_1:4_S11V,kka2_1:4_11,Kka2,kka2_1:4,P00552,,YES,11,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.322,-2.388,0.066,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.168804,0.00381691,0.940496 kka2_1:4_S204P,kka2_1:4_204,Kka2,kka2_1:4,P00552,,YES,204,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.353,-3.82,2.467,,0.144,E,A,0.27,-1.2,2.442,,65.53,HPO,-0.953333,0.168804,0.00881794,0.447567 kka2_1:4_S204Q,kka2_1:4_204,Kka2,kka2_1:4,P00552,,YES,204,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.353,-3.954,2.601,,0.144,E,A,0.27,-1.2,2.442,,65.53,HPO,-0.953333,0.168804,0.00881794,0.45279 kka2_1:4_S204Y,kka2_1:4_204,Kka2,kka2_1:4,P00552,,YES,204,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.353,-4.328,2.975,,0.144,E,A,0.27,-1.2,2.442,,65.53,HPO,-0.953333,0.168804,0.00881794,0.486491 kka2_1:4_S251A,kka2_1:4_251,Kka2,kka2_1:4,P00552,,YES,251,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.636,-2.138,-0.498,,0.712,H,A,0.77,-0.25,,,71.59,APP,-2.09367,0.168804,0.0138916,1.06895 kka2_1:4_S251Q,kka2_1:4_251,Kka2,kka2_1:4,P00552,,YES,251,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.636,-2.668,0.032,,0.712,H,A,0.77,-0.25,,,71.59,APP,-2.09367,0.168804,0.0138916,1.00376 kka2_1:4_S32D,kka2_1:4_32,Kka2,kka2_1:4,P00552,,YES,32,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-0.804,-3.272,2.468,,0.768,S,b,0.27,3.75,,,,OPA,-1.74533,0.168804,0.00149998,0.431859 kka2_1:4_S32W,kka2_1:4_32,Kka2,kka2_1:4,P00552,,YES,32,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-0.804,-5.351,4.547,,0.768,S,b,0.27,3.75,,,,OPA,-1.74533,0.168804,0.00149998,0.46636 kka2_1:4_S40F,kka2_1:4_40,Kka2,kka2_1:4,P00552,,YES,40,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.645,-4.453,1.808,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.168804,0.00693477,0.765487 kka2_1:4_S54A,kka2_1:4_54,Kka2,kka2_1:4,P00552,,YES,54,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.471,-1.705,-0.766,,0.408,S,b,0.27,1.01,17.332,17.332,71.59,HPO,-2.259,0.168804,0.00782867,1.00188 kka2_1:4_S54D,kka2_1:4_54,Kka2,kka2_1:4,P00552,,YES,54,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.471,-2.887,0.416,,0.408,S,b,0.27,1.01,17.332,17.332,71.59,HPO,-2.259,0.168804,0.00782867,0.765124 kka2_1:4_S54E,kka2_1:4_54,Kka2,kka2_1:4,P00552,,YES,54,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.471,-3.63,1.159,,0.408,S,b,0.27,1.01,17.332,17.332,71.59,HPO,-2.259,0.168804,0.00782867,0.783073 kka2_1:4_S54F,kka2_1:4_54,Kka2,kka2_1:4,P00552,,YES,54,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.471,-4.27,1.799,,0.408,S,b,0.27,1.01,17.332,17.332,71.59,HPO,-2.259,0.168804,0.00782867,0.785536 kka2_1:4_S54H,kka2_1:4_54,Kka2,kka2_1:4,P00552,,YES,54,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.471,-3.515,1.044,,0.408,S,b,0.27,1.01,17.332,17.332,71.59,HPO,-2.259,0.168804,0.00782867,0.822458 kka2_1:4_S54L,kka2_1:4_54,Kka2,kka2_1:4,P00552,,YES,54,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.471,-2.689,0.218,,0.408,S,b,0.27,1.01,17.332,17.332,71.59,HPO,-2.259,0.168804,0.00782867,0.83121 kka2_1:4_S54P,kka2_1:4_54,Kka2,kka2_1:4,P00552,,YES,54,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.471,-4.062,1.591,,0.408,S,b,0.27,1.01,17.332,17.332,71.59,HPO,-2.259,0.168804,0.00782867,0.687564 kka2_1:4_S54Q,kka2_1:4_54,Kka2,kka2_1:4,P00552,,YES,54,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.471,-3.041,0.57,,0.408,S,b,0.27,1.01,17.332,17.332,71.59,HPO,-2.259,0.168804,0.00782867,0.813651 kka2_1:4_S54V,kka2_1:4_54,Kka2,kka2_1:4,P00552,,YES,54,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.471,-2.309,-0.162,,0.408,S,b,0.27,1.01,17.332,17.332,71.59,HPO,-2.259,0.168804,0.00782867,0.925757 kka2_1:4_S68A,kka2_1:4_68,Kka2,kka2_1:4,P00552,,YES,68,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.623,-3.303,0.68,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.168804,0.00608265,0.851739 kka2_1:4_S68D,kka2_1:4_68,Kka2,kka2_1:4,P00552,,YES,68,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.623,-2.48,-0.143,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.168804,0.00608265,0.881015 kka2_1:4_S68E,kka2_1:4_68,Kka2,kka2_1:4,P00552,,YES,68,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.623,-2.442,-0.181,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.168804,0.00608265,0.909797 kka2_1:4_S68H,kka2_1:4_68,Kka2,kka2_1:4,P00552,,YES,68,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.623,-3.15,0.527,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.168804,0.00608265,0.866155 kka2_1:4_S68K,kka2_1:4_68,Kka2,kka2_1:4,P00552,,YES,68,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.623,-2.899,0.276,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.168804,0.00608265,0.883077 kka2_1:4_S68L,kka2_1:4_68,Kka2,kka2_1:4,P00552,,YES,68,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.623,-2.822,0.199,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.168804,0.00608265,0.86546 kka2_1:4_S68M,kka2_1:4_68,Kka2,kka2_1:4,P00552,,YES,68,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.623,-4.761,2.138,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.168804,0.00608265,0.838585 kka2_1:4_S68P,kka2_1:4_68,Kka2,kka2_1:4,P00552,,YES,68,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.623,-4.076,1.453,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.168804,0.00608265,0.706916 kka2_1:4_S68Q,kka2_1:4_68,Kka2,kka2_1:4,P00552,,YES,68,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.623,-2.944,0.321,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.168804,0.00608265,0.875782 kka2_1:4_S68V,kka2_1:4_68,Kka2,kka2_1:4,P00552,,YES,68,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.623,-3.127,0.504,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.168804,0.00608265,0.840033 kka2_1:4_S68W,kka2_1:4_68,Kka2,kka2_1:4,P00552,,YES,68,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.623,-5.546,2.923,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.168804,0.00608265,0.79465 kka2_1:4_S68Y,kka2_1:4_68,Kka2,kka2_1:4,P00552,,YES,68,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.623,-4.344,1.721,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.168804,0.00608265,0.766384 kka2_1:4_T125D,kka2_1:4_125,Kka2,kka2_1:4,P00552,,YES,125,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.622,-2.647,0.025,,0.791,T,A,0.82,0.33,1.612,,92.05,BPH,-1.56933,0.168804,0.00821755,0.848327 kka2_1:4_T125E,kka2_1:4_125,Kka2,kka2_1:4,P00552,,YES,125,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.622,-2.741,0.119,,0.791,T,A,0.82,0.33,1.612,,92.05,BPH,-1.56933,0.168804,0.00821755,0.831446 kka2_1:4_T125H,kka2_1:4_125,Kka2,kka2_1:4,P00552,,YES,125,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.622,-4.735,2.113,,0.791,T,A,0.82,0.33,1.612,,92.05,BPH,-1.56933,0.168804,0.00821755,0.8782 kka2_1:4_T125Q,kka2_1:4_125,Kka2,kka2_1:4,P00552,,YES,125,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.622,-2.465,-0.157,,0.791,T,A,0.82,0.33,1.612,,92.05,BPH,-1.56933,0.168804,0.00821755,0.87061 kka2_1:4_T125R,kka2_1:4_125,Kka2,kka2_1:4,P00552,,YES,125,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.622,-2.191,-0.431,,0.791,T,A,0.82,0.33,1.612,,92.05,BPH,-1.56933,0.168804,0.00821755,0.922365 kka2_1:4_T125W,kka2_1:4_125,Kka2,kka2_1:4,P00552,,YES,125,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.622,-5.542,2.92,,0.791,T,A,0.82,0.33,1.612,,92.05,BPH,-1.56933,0.168804,0.00821755,0.814491 kka2_1:4_T130D,kka2_1:4_130,Kka2,kka2_1:4,P00552,,YES,130,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.392,-2.708,0.316,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.168804,0.00804204,0.761873 kka2_1:4_T130E,kka2_1:4_130,Kka2,kka2_1:4,P00552,,YES,130,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.392,-3.049,0.657,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.168804,0.00804204,0.756474 kka2_1:4_T130F,kka2_1:4_130,Kka2,kka2_1:4,P00552,,YES,130,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.392,-4.384,1.992,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.168804,0.00804204,0.832351 kka2_1:4_T130G,kka2_1:4_130,Kka2,kka2_1:4,P00552,,YES,130,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.392,-2.278,-0.114,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.168804,0.00804204,0.826008 kka2_1:4_T130L,kka2_1:4_130,Kka2,kka2_1:4,P00552,,YES,130,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.392,-2.848,0.456,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.168804,0.00804204,0.769406 kka2_1:4_T130Q,kka2_1:4_130,Kka2,kka2_1:4,P00552,,YES,130,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.392,-3.316,0.924,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.168804,0.00804204,0.79947 kka2_1:4_T130R,kka2_1:4_130,Kka2,kka2_1:4,P00552,,YES,130,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.392,-3.981,1.589,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.168804,0.00804204,0.791695 kka2_1:4_T130V,kka2_1:4_130,Kka2,kka2_1:4,P00552,,YES,130,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.392,-3.647,1.255,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.168804,0.00804204,0.775232 kka2_1:4_T130Y,kka2_1:4_130,Kka2,kka2_1:4,P00552,,YES,130,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.392,-4.42,2.028,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.168804,0.00804204,0.842567 kka2_1:4_T146E,kka2_1:4_146,Kka2,kka2_1:4,P00552,,YES,146,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.978,-2.468,-0.51,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.168804,0.00606474,0.907272 kka2_1:4_T146G,kka2_1:4_146,Kka2,kka2_1:4,P00552,,YES,146,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.978,-3.466,0.488,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.168804,0.00606474,0.725878 kka2_1:4_T146H,kka2_1:4_146,Kka2,kka2_1:4,P00552,,YES,146,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.978,-4.762,1.784,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.168804,0.00606474,0.742487 kka2_1:4_T146L,kka2_1:4_146,Kka2,kka2_1:4,P00552,,YES,146,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.978,-2.714,-0.264,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.168804,0.00606474,0.845861 kka2_1:4_T146V,kka2_1:4_146,Kka2,kka2_1:4,P00552,,YES,146,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.978,-2.951,-0.027,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.168804,0.00606474,0.817302 kka2_1:4_T225G,kka2_1:4_225,Kka2,kka2_1:4,P00552,,YES,225,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.393,-3.525,1.132,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.168804,0.0113598,0.449114 kka2_1:4_T28H,kka2_1:4_28,Kka2,kka2_1:4,P00552,,YES,28,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.883,-3.548,1.665,,0.353,S,B,0.82,2.02,4.415,,63.64,PPH,-1.74467,0.168804,0.00743084,0.607401 kka2_1:4_T28L,kka2_1:4_28,Kka2,kka2_1:4,P00552,,YES,28,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.883,-2.972,1.089,,0.353,S,B,0.82,2.02,4.415,,63.64,PPH,-1.74467,0.168804,0.00743084,0.651138 kka2_1:4_T28P,kka2_1:4_28,Kka2,kka2_1:4,P00552,,YES,28,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.883,-3.202,1.319,,0.353,S,B,0.82,2.02,4.415,,63.64,PPH,-1.74467,0.168804,0.00743084,0.577969 kka2_1:4_T28V,kka2_1:4_28,Kka2,kka2_1:4,P00552,,YES,28,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.883,-2.663,0.78,,0.353,S,B,0.82,2.02,4.415,,63.64,PPH,-1.74467,0.168804,0.00743084,0.701225 kka2_1:4_T51G,kka2_1:4_51,Kka2,kka2_1:4,P00552,,YES,51,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.199,-2.948,0.749,,0.05,E,B,0.82,-0.05,13.165,13.165,63.64,BPA,-1.76767,0.168804,0.00628861,0.564506 kka2_1:4_T51L,kka2_1:4_51,Kka2,kka2_1:4,P00552,,YES,51,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.199,-2.881,0.682,,0.05,E,B,0.82,-0.05,13.165,13.165,63.64,BPA,-1.76767,0.168804,0.00628861,0.5795 kka2_1:4_T51P,kka2_1:4_51,Kka2,kka2_1:4,P00552,,YES,51,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.199,-4.078,1.879,,0.05,E,B,0.82,-0.05,13.165,13.165,63.64,BPA,-1.76767,0.168804,0.00628861,0.462561 kka2_1:4_T51R,kka2_1:4_51,Kka2,kka2_1:4,P00552,,YES,51,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.199,-3.007,0.808,,0.05,E,B,0.82,-0.05,13.165,13.165,63.64,BPA,-1.76767,0.168804,0.00628861,0.552795 kka2_1:4_T51V,kka2_1:4_51,Kka2,kka2_1:4,P00552,,YES,51,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.199,-2.337,0.138,,0.05,E,B,0.82,-0.05,13.165,13.165,63.64,BPA,-1.76767,0.168804,0.00628861,0.666997 kka2_1:4_T51W,kka2_1:4_51,Kka2,kka2_1:4,P00552,,YES,51,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.199,-5.512,3.313,,0.05,E,B,0.82,-0.05,13.165,13.165,63.64,BPA,-1.76767,0.168804,0.00628861,0.545297 kka2_1:4_T72C,kka2_1:4_72,Kka2,kka2_1:4,P00552,,YES,72,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.38,-5.141,2.761,,0.784,H,A,0.82,0.29,6.463,,65.53,HPP,-2.238,0.168804,0.00750756,0.755017 kka2_1:4_T72G,kka2_1:4_72,Kka2,kka2_1:4,P00552,,YES,72,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.38,-2.12,-0.26,,0.784,H,A,0.82,0.29,6.463,,65.53,HPP,-2.238,0.168804,0.00750756,0.866277 kka2_1:4_T72R,kka2_1:4_72,Kka2,kka2_1:4,P00552,,YES,72,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.38,-2.467,0.087,,0.784,H,A,0.82,0.29,6.463,,65.53,HPP,-2.238,0.168804,0.00750756,0.836384 kka2_1:4_T72S,kka2_1:4_72,Kka2,kka2_1:4,P00552,,YES,72,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.38,-2.339,-0.041,,0.784,H,A,0.82,0.29,6.463,,65.53,HPP,-2.238,0.168804,0.00750756,0.855667 kka2_1:4_T85D,kka2_1:4_85,Kka2,kka2_1:4,P00552,,YES,85,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.165,-2.694,0.529,,0.576,E,B,0.22,1.39,1.853,,71.59,HPA,-2.10133,0.168804,0.00634493,0.720062 kka2_1:4_T85F,kka2_1:4_85,Kka2,kka2_1:4,P00552,,YES,85,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.165,-3.388,1.223,,0.576,E,B,0.22,1.39,1.853,,71.59,HPA,-2.10133,0.168804,0.00634493,0.75288 kka2_1:4_T85G,kka2_1:4_85,Kka2,kka2_1:4,P00552,,YES,85,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.165,-3.601,1.436,,0.576,E,B,0.22,1.39,1.853,,71.59,HPA,-2.10133,0.168804,0.00634493,0.745847 kka2_1:4_T85H,kka2_1:4_85,Kka2,kka2_1:4,P00552,,YES,85,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.165,-3.24,1.075,,0.576,E,B,0.22,1.39,1.853,,71.59,HPA,-2.10133,0.168804,0.00634493,0.745965 kka2_1:4_T85K,kka2_1:4_85,Kka2,kka2_1:4,P00552,,YES,85,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.165,-3.032,0.867,,0.576,E,B,0.22,1.39,1.853,,71.59,HPA,-2.10133,0.168804,0.00634493,0.74637 kka2_1:4_T85Q,kka2_1:4_85,Kka2,kka2_1:4,P00552,,YES,85,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.165,-2.53,0.365,,0.576,E,B,0.22,1.39,1.853,,71.59,HPA,-2.10133,0.168804,0.00634493,0.755864 kka2_1:4_T85V,kka2_1:4_85,Kka2,kka2_1:4,P00552,,YES,85,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.165,-2.678,0.513,,0.576,E,B,0.22,1.39,1.853,,71.59,HPA,-2.10133,0.168804,0.00634493,0.727526 kka2_1:4_T85W,kka2_1:4_85,Kka2,kka2_1:4,P00552,,YES,85,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.165,-5.494,3.329,,0.576,E,B,0.22,1.39,1.853,,71.59,HPA,-2.10133,0.168804,0.00634493,0.766112 kka2_1:4_T85Y,kka2_1:4_85,Kka2,kka2_1:4,P00552,,YES,85,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.165,-4.263,2.098,,0.576,E,B,0.22,1.39,1.853,,71.59,HPA,-2.10133,0.168804,0.00634493,0.77107 kka2_1:4_V113F,kka2_1:4_113,Kka2,kka2_1:4,P00552,,YES,113,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.233,-3.907,2.674,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.168804,0.00650191,0.38936 kka2_1:4_V113S,kka2_1:4_113,Kka2,kka2_1:4,P00552,,YES,113,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.233,-3.696,2.463,,0.008,H,A,0.44,-1.17,1.387,,52.27,BHP,-2.08367,0.168804,0.00650191,0.439132 kka2_1:4_V153T,kka2_1:4_153,Kka2,kka2_1:4,P00552,,YES,153,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.092,-3.365,2.273,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.168804,0.00501119,0.521741 kka2_1:4_V153Y,kka2_1:4_153,Kka2,kka2_1:4,P00552,,YES,153,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.092,-4.06,2.968,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.168804,0.00501119,0.45802 kka2_1:4_V16C,kka2_1:4_16,Kka2,kka2_1:4,P00552,,YES,16,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-3.087,-3.613,0.526,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.168804,0.00694011,0.841825 kka2_1:4_V16K,kka2_1:4_16,Kka2,kka2_1:4,P00552,,YES,16,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-3.087,-2.781,-0.306,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.168804,0.00694011,0.903515 kka2_1:4_V16N,kka2_1:4_16,Kka2,kka2_1:4,P00552,,YES,16,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-3.087,-3.138,0.051,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.168804,0.00694011,0.860781 kka2_1:4_V16R,kka2_1:4_16,Kka2,kka2_1:4,P00552,,YES,16,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-3.087,-1.961,-1.126,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.168804,0.00694011,0.963996 kka2_1:4_V16T,kka2_1:4_16,Kka2,kka2_1:4,P00552,,YES,16,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-3.087,-3.05,-0.037,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.168804,0.00694011,0.857264 kka2_1:4_V16Y,kka2_1:4_16,Kka2,kka2_1:4,P00552,,YES,16,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-3.087,-4.365,1.278,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.168804,0.00694011,0.861802 kka2_1:4_V214Q,kka2_1:4_214,Kka2,kka2_1:4,P00552,,YES,214,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.261,-4.289,3.028,,0.117,E,B,0.44,-0.31,0.921,,64.39,OHH,-0.941667,0.168804,0.00692782,0.481625 kka2_1:4_V242P,kka2_1:4_242,Kka2,kka2_1:4,P00552,,YES,242,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-2.687,-4.019,1.332,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.168804,0.0102575,0.842752 kka2_1:4_V242Y,kka2_1:4_242,Kka2,kka2_1:4,P00552,,YES,242,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-2.687,-4.381,1.694,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.168804,0.0102575,0.972014 kka2_1:4_V36K,kka2_1:4_36,Kka2,kka2_1:4,P00552,,YES,36,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-0.898,-3.793,2.895,,0.292,E,B,0.44,0.21,0.278,,52.27,HHH,-1.484,0.168804,0.00245633,0.411288 kka2_1:4_V46H,kka2_1:4_46,Kka2,kka2_1:4,P00552,,YES,46,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-2.62,-3.614,0.994,,0.192,.,B,0.44,-1.12,9.564,,92.05,OHH,-1.88633,0.168804,0.00631301,0.72029 kka2_1:4_V46Y,kka2_1:4_46,Kka2,kka2_1:4,P00552,,YES,46,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-2.62,-4.392,1.772,,0.192,.,B,0.44,-1.12,9.564,,92.05,OHH,-1.88633,0.168804,0.00631301,0.681022 kka2_1:4_V75Q,kka2_1:4_75,Kka2,kka2_1:4,P00552,,YES,75,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-2.06,-2.734,0.674,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.168804,0.00693733,0.677113 kka2_1:4_V83H,kka2_1:4_83,Kka2,kka2_1:4,P00552,,YES,83,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-2.567,-2.84,0.273,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.168804,0.00650486,0.828813 kka2_1:4_V83I,kka2_1:4_83,Kka2,kka2_1:4,P00552,,YES,83,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-2.567,-3.777,1.21,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.168804,0.00650486,0.705317 kka2_1:4_V83N,kka2_1:4_83,Kka2,kka2_1:4,P00552,,YES,83,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-2.567,-3.217,0.65,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.168804,0.00650486,0.774893 kka2_1:4_V83R,kka2_1:4_83,Kka2,kka2_1:4,P00552,,YES,83,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-2.567,-2.854,0.287,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.168804,0.00650486,0.827141 kka2_1:4_V83S,kka2_1:4_83,Kka2,kka2_1:4,P00552,,YES,83,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-2.567,-2.85,0.283,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.168804,0.00650486,0.802617 kka2_1:4_V83T,kka2_1:4_83,Kka2,kka2_1:4,P00552,,YES,83,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-2.567,-2.28,-0.287,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.168804,0.00650486,0.893546 kka2_1:4_V83W,kka2_1:4_83,Kka2,kka2_1:4,P00552,,YES,83,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-2.567,-5.342,2.775,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.168804,0.00650486,0.773241 kka2_1:4_V84C,kka2_1:4_84,Kka2,kka2_1:4,P00552,,YES,84,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-2.279,-5.009,2.73,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.168804,0.00724019,0.846613 kka2_1:4_V84D,kka2_1:4_84,Kka2,kka2_1:4,P00552,,YES,84,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-2.279,-2.613,0.334,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.168804,0.00724019,0.739967 kka2_1:4_V84E,kka2_1:4_84,Kka2,kka2_1:4,P00552,,YES,84,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-2.279,-2.088,-0.191,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.168804,0.00724019,0.846607 kka2_1:4_V84N,kka2_1:4_84,Kka2,kka2_1:4,P00552,,YES,84,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-2.279,-3.883,1.604,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.168804,0.00724019,0.713334 kka2_1:4_V84Q,kka2_1:4_84,Kka2,kka2_1:4,P00552,,YES,84,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-2.279,-3.218,0.939,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.168804,0.00724019,0.750665 kka2_1:4_V84R,kka2_1:4_84,Kka2,kka2_1:4,P00552,,YES,84,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-2.279,-3.996,1.717,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.168804,0.00724019,0.707715 kka2_1:4_V84T,kka2_1:4_84,Kka2,kka2_1:4,P00552,,YES,84,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-2.279,-2.154,-0.125,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.168804,0.00724019,0.866453 kka2_1:4_V84W,kka2_1:4_84,Kka2,kka2_1:4,P00552,,YES,84,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-2.279,-5.522,3.243,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.168804,0.00724019,0.747401 kka2_1:4_V84Y,kka2_1:4_84,Kka2,kka2_1:4,P00552,,YES,84,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-2.279,-4.308,2.029,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.168804,0.00724019,0.71605 kka2_1:4_V97S,kka2_1:4_97,Kka2,kka2_1:4,P00552,,YES,97,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.453,-3.709,2.256,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.168804,0.00737869,0.484908 kka2_1:4_V97T,kka2_1:4_97,Kka2,kka2_1:4,P00552,,YES,97,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.453,-3.491,2.038,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.168804,0.00737869,0.497467 kka2_1:4_W15A,kka2_1:4_15,Kka2,kka2_1:4,P00552,,YES,15,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-1.392,-3.416,2.024,,0.01,G,A,0.47,0.15,0.943,,52.27,HHH,-2.10533,0.168804,0.00585505,0.519581 kka2_1:4_W15E,kka2_1:4_15,Kka2,kka2_1:4,P00552,,YES,15,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-1.392,-4.005,2.613,,0.01,G,A,0.47,0.15,0.943,,52.27,HHH,-2.10533,0.168804,0.00585505,0.438613 kka2_1:4_W15H,kka2_1:4_15,Kka2,kka2_1:4,P00552,,YES,15,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-1.392,-4.848,3.456,,0.01,G,A,0.47,0.15,0.943,,52.27,HHH,-2.10533,0.168804,0.00585505,0.472759 kka2_1:4_W15I,kka2_1:4_15,Kka2,kka2_1:4,P00552,,YES,15,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-1.392,-2.748,1.356,,0.01,G,A,0.47,0.15,0.943,,52.27,HHH,-2.10533,0.168804,0.00585505,0.510319 kka2_1:4_W236V,kka2_1:4_236,Kka2,kka2_1:4,P00552,,YES,236,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-1.363,-3.56,2.197,,0.303,H,A,0.47,-0.76,2.277,,48.48,AHH,-1.81267,0.168804,0.0088796,0.478096 kka2_1:4_W24K,kka2_1:4_24,Kka2,kka2_1:4,P00552,,YES,24,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-1.779,-4.012,2.233,,0.477,E,B,1.51,-0.21,2.666,,56.06,AHH,-2.24467,0.168804,0.00631564,0.434711 kka2_1:4_W69A,kka2_1:4_69,Kka2,kka2_1:4,P00552,,YES,69,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-0.859,-3.554,2.695,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.168804,0.0012874,0.451504 kka2_1:4_W69E,kka2_1:4_69,Kka2,kka2_1:4,P00552,,YES,69,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-0.859,-3.916,3.057,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.168804,0.0012874,0.403198 kka2_1:4_W69I,kka2_1:4_69,Kka2,kka2_1:4,P00552,,YES,69,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-0.859,-4.006,3.147,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.168804,0.0012874,0.387656 kka2_1:4_W69K,kka2_1:4_69,Kka2,kka2_1:4,P00552,,YES,69,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-0.859,-3.933,3.074,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.168804,0.0012874,0.402039 kka2_1:4_W69S,kka2_1:4_69,Kka2,kka2_1:4,P00552,,YES,69,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-0.859,-3.862,3.003,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.168804,0.0012874,0.463082 kka2_1:4_W91K,kka2_1:4_91,Kka2,kka2_1:4,P00552,,YES,91,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-1.178,-3.72,2.542,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.168804,0.00358653,0.482402 kka2_1:4_W91T,kka2_1:4_91,Kka2,kka2_1:4,P00552,,YES,91,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-1.178,-3.718,2.54,,0.077,E,B,0.47,0.27,0.893,,48.48,AHH,-1.51,0.168804,0.00358653,0.534507 kka2_1:4_Y218A,kka2_1:4_218,Kka2,kka2_1:4,P00552,,YES,218,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-1.438,-2.767,1.329,,0.122,H,A,0.21,-0.69,1.022,,56.06,BHP,-1.17533,0.168804,0.0126098,0.517785 kka2_1:4_Y218Q,kka2_1:4_218,Kka2,kka2_1:4,P00552,,YES,218,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-1.438,-4.079,2.641,,0.122,H,A,0.21,-0.69,1.022,,56.06,BHP,-1.17533,0.168804,0.0126098,0.480391 kka2_1:4_Y22A,kka2_1:4_22,Kka2,kka2_1:4,P00552,,YES,22,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-1.583,-1.97,0.387,,0.122,.,B,0.21,-0.8,1.838,,65.53,OHA,-1.80333,0.168804,0.00598977,0.628086 kka2_1:4_Y22T,kka2_1:4_22,Kka2,kka2_1:4,P00552,,YES,22,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-1.583,-2.95,1.367,,0.122,.,B,0.21,-0.8,1.838,,65.53,OHA,-1.80333,0.168804,0.00598977,0.550501 kka2_1:4_Y22V,kka2_1:4_22,Kka2,kka2_1:4,P00552,,YES,22,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-1.583,-3.487,1.904,,0.122,.,B,0.21,-0.8,1.838,,65.53,OHA,-1.80333,0.168804,0.00598977,0.516043 kka2_1:8_A108K,kka2_1:8_108,Kka2,kka2_1:8,P00552,,YES,108,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.061,-3.668,1.607,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.100394,0.00751209,0.599195 kka2_1:8_A108K,kka2_1:8_108,Kka2,kka2_1:8,P00552,,YES,108,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.061,-3.668,1.607,,0.243,.,B,0.46,-1.34,0.348,,71.59,HHO,-1.57033,0.100394,0.00751209,0.599195 kka2_1:8_A110C,kka2_1:8_110,Kka2,kka2_1:8,P00552,,YES,110,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.064,-5.167,3.103,,0.175,H,A,1.04,-1.19,11.413,11.413,71.59,OHA,-1.91867,0.100394,0.00759851,0.750716 kka2_1:8_A110C,kka2_1:8_110,Kka2,kka2_1:8,P00552,,YES,110,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.064,-5.167,3.103,,0.175,H,A,1.04,-1.19,11.413,11.413,71.59,OHA,-1.91867,0.100394,0.00759851,0.750716 kka2_1:8_A117I,kka2_1:8_117,Kka2,kka2_1:8,P00552,,YES,117,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.828,-3.432,2.604,,,H,A,1.04,-0.78,0.755,,45.83,HHA,-1.79333,0.100394,0.00282984,0.426636 kka2_1:8_A117I,kka2_1:8_117,Kka2,kka2_1:8,P00552,,YES,117,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.828,-3.432,2.604,,,H,A,1.04,-0.78,0.755,,45.83,HHA,-1.79333,0.100394,0.00282984,0.426636 kka2_1:8_A119F,kka2_1:8_119,Kka2,kka2_1:8,P00552,,YES,119,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.073,-4.171,3.098,,0.019,H,A,0.46,-0.57,1.511,,71.59,AHH,-2.34,0.100394,0.00441074,0.438256 kka2_1:8_A119F,kka2_1:8_119,Kka2,kka2_1:8,P00552,,YES,119,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.073,-4.171,3.098,,0.019,H,A,0.46,-0.57,1.511,,71.59,AHH,-2.34,0.100394,0.00441074,0.438256 kka2_1:8_A119H,kka2_1:8_119,Kka2,kka2_1:8,P00552,,YES,119,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.073,-4.774,3.701,,0.019,H,A,0.46,-0.57,1.511,,71.59,AHH,-2.34,0.100394,0.00441074,0.476641 kka2_1:8_A119H,kka2_1:8_119,Kka2,kka2_1:8,P00552,,YES,119,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.073,-4.774,3.701,,0.019,H,A,0.46,-0.57,1.511,,71.59,AHH,-2.34,0.100394,0.00441074,0.476641 kka2_1:8_A119I,kka2_1:8_119,Kka2,kka2_1:8,P00552,,YES,119,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.073,-3.591,2.518,,0.019,H,A,0.46,-0.57,1.511,,71.59,AHH,-2.34,0.100394,0.00441074,0.442677 kka2_1:8_A119I,kka2_1:8_119,Kka2,kka2_1:8,P00552,,YES,119,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.073,-3.591,2.518,,0.019,H,A,0.46,-0.57,1.511,,71.59,AHH,-2.34,0.100394,0.00441074,0.442677 kka2_1:8_A119N,kka2_1:8_119,Kka2,kka2_1:8,P00552,,YES,119,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.073,-3.831,2.758,,0.019,H,A,0.46,-0.57,1.511,,71.59,AHH,-2.34,0.100394,0.00441074,0.436449 kka2_1:8_A119N,kka2_1:8_119,Kka2,kka2_1:8,P00552,,YES,119,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.073,-3.831,2.758,,0.019,H,A,0.46,-0.57,1.511,,71.59,AHH,-2.34,0.100394,0.00441074,0.436449 kka2_1:8_A129C,kka2_1:8_129,Kka2,kka2_1:8,P00552,,YES,129,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.656,-5.053,3.397,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.100394,0.00726862,0.80658 kka2_1:8_A129C,kka2_1:8_129,Kka2,kka2_1:8,P00552,,YES,129,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.656,-5.053,3.397,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.100394,0.00726862,0.80658 kka2_1:8_A129F,kka2_1:8_129,Kka2,kka2_1:8,P00552,,YES,129,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.656,-4.391,2.735,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.100394,0.00726862,0.796528 kka2_1:8_A129F,kka2_1:8_129,Kka2,kka2_1:8,P00552,,YES,129,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.656,-4.391,2.735,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.100394,0.00726862,0.796528 kka2_1:8_A129H,kka2_1:8_129,Kka2,kka2_1:8,P00552,,YES,129,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.656,-3.201,1.545,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.100394,0.00726862,0.762131 kka2_1:8_A129H,kka2_1:8_129,Kka2,kka2_1:8,P00552,,YES,129,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.656,-3.201,1.545,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.100394,0.00726862,0.762131 kka2_1:8_A129K,kka2_1:8_129,Kka2,kka2_1:8,P00552,,YES,129,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.656,-3.023,1.367,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.100394,0.00726862,0.765339 kka2_1:8_A129K,kka2_1:8_129,Kka2,kka2_1:8,P00552,,YES,129,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.656,-3.023,1.367,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.100394,0.00726862,0.765339 kka2_1:8_A129N,kka2_1:8_129,Kka2,kka2_1:8,P00552,,YES,129,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.656,-2.9,1.244,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.100394,0.00726862,0.766948 kka2_1:8_A129N,kka2_1:8_129,Kka2,kka2_1:8,P00552,,YES,129,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.656,-2.9,1.244,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.100394,0.00726862,0.766948 kka2_1:8_A129R,kka2_1:8_129,Kka2,kka2_1:8,P00552,,YES,129,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.656,-2.972,1.316,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.100394,0.00726862,0.771802 kka2_1:8_A129R,kka2_1:8_129,Kka2,kka2_1:8,P00552,,YES,129,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.656,-2.972,1.316,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.100394,0.00726862,0.771802 kka2_1:8_A129Y,kka2_1:8_129,Kka2,kka2_1:8,P00552,,YES,129,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.656,-4.374,2.718,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.100394,0.00726862,0.795545 kka2_1:8_A129Y,kka2_1:8_129,Kka2,kka2_1:8,P00552,,YES,129,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.656,-4.374,2.718,,0.845,G,A,0.46,0.72,2.444,,92.05,OHP,-1.99,0.100394,0.00726862,0.795545 kka2_1:8_A13H,kka2_1:8_13,Kka2,kka2_1:8,P00552,,YES,13,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.248,-3.721,1.473,,0.689,G,A,1.04,0.99,14.966,14.966,92.05,OHH,-1.646,0.100394,0.00784241,0.894894 kka2_1:8_A13H,kka2_1:8_13,Kka2,kka2_1:8,P00552,,YES,13,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.248,-3.721,1.473,,0.689,G,A,1.04,0.99,14.966,14.966,92.05,OHH,-1.646,0.100394,0.00784241,0.894894 kka2_1:8_A13K,kka2_1:8_13,Kka2,kka2_1:8,P00552,,YES,13,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.248,-3.012,0.764,,0.689,G,A,1.04,0.99,14.966,14.966,92.05,OHH,-1.646,0.100394,0.00784241,0.915372 kka2_1:8_A13K,kka2_1:8_13,Kka2,kka2_1:8,P00552,,YES,13,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.248,-3.012,0.764,,0.689,G,A,1.04,0.99,14.966,14.966,92.05,OHH,-1.646,0.100394,0.00784241,0.915372 kka2_1:8_A13L,kka2_1:8_13,Kka2,kka2_1:8,P00552,,YES,13,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.248,-2.945,0.697,,0.689,G,A,1.04,0.99,14.966,14.966,92.05,OHH,-1.646,0.100394,0.00784241,0.906595 kka2_1:8_A13L,kka2_1:8_13,Kka2,kka2_1:8,P00552,,YES,13,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-2.248,-2.945,0.697,,0.689,G,A,1.04,0.99,14.966,14.966,92.05,OHH,-1.646,0.100394,0.00784241,0.906595 kka2_1:8_A13N,kka2_1:8_13,Kka2,kka2_1:8,P00552,,YES,13,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.248,-3.116,0.868,,0.689,G,A,1.04,0.99,14.966,14.966,92.05,OHH,-1.646,0.100394,0.00784241,0.932128 kka2_1:8_A13N,kka2_1:8_13,Kka2,kka2_1:8,P00552,,YES,13,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.248,-3.116,0.868,,0.689,G,A,1.04,0.99,14.966,14.966,92.05,OHH,-1.646,0.100394,0.00784241,0.932128 kka2_1:8_A13Y,kka2_1:8_13,Kka2,kka2_1:8,P00552,,YES,13,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.248,-4.443,2.195,,0.689,G,A,1.04,0.99,14.966,14.966,92.05,OHH,-1.646,0.100394,0.00784241,0.932029 kka2_1:8_A13Y,kka2_1:8_13,Kka2,kka2_1:8,P00552,,YES,13,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.248,-4.443,2.195,,0.689,G,A,1.04,0.99,14.966,14.966,92.05,OHH,-1.646,0.100394,0.00784241,0.932029 kka2_1:8_A144I,kka2_1:8_144,Kka2,kka2_1:8,P00552,,YES,144,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.859,-3.396,2.537,,,H,A,1.04,0.21,1.118,,52.65,BHB,-1.72933,0.100394,0.00231095,0.433466 kka2_1:8_A144I,kka2_1:8_144,Kka2,kka2_1:8,P00552,,YES,144,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.859,-3.396,2.537,,,H,A,1.04,0.21,1.118,,52.65,BHB,-1.72933,0.100394,0.00231095,0.433466 kka2_1:8_A144P,kka2_1:8_144,Kka2,kka2_1:8,P00552,,YES,144,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.859,-3.765,2.906,,,H,A,1.04,0.21,1.118,,52.65,BHB,-1.72933,0.100394,0.00231095,0.463617 kka2_1:8_A144P,kka2_1:8_144,Kka2,kka2_1:8,P00552,,YES,144,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-0.859,-3.765,2.906,,,H,A,1.04,0.21,1.118,,52.65,BHB,-1.72933,0.100394,0.00231095,0.463617 kka2_1:8_A14C,kka2_1:8_14,Kka2,kka2_1:8,P00552,,YES,14,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.837,-5.018,3.181,,0.728,G,A,0.46,0.7,,,71.59,HHH,-1.82567,0.100394,0.00706614,0.822262 kka2_1:8_A14C,kka2_1:8_14,Kka2,kka2_1:8,P00552,,YES,14,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.837,-5.018,3.181,,0.728,G,A,0.46,0.7,,,71.59,HHH,-1.82567,0.100394,0.00706614,0.822262 kka2_1:8_A14F,kka2_1:8_14,Kka2,kka2_1:8,P00552,,YES,14,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.837,-4.392,2.555,,0.728,G,A,0.46,0.7,,,71.59,HHH,-1.82567,0.100394,0.00706614,0.802052 kka2_1:8_A14F,kka2_1:8_14,Kka2,kka2_1:8,P00552,,YES,14,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.837,-4.392,2.555,,0.728,G,A,0.46,0.7,,,71.59,HHH,-1.82567,0.100394,0.00706614,0.802052 kka2_1:8_A14N,kka2_1:8_14,Kka2,kka2_1:8,P00552,,YES,14,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.837,-3.807,1.97,,0.728,G,A,0.46,0.7,,,71.59,HHH,-1.82567,0.100394,0.00706614,0.805751 kka2_1:8_A14N,kka2_1:8_14,Kka2,kka2_1:8,P00552,,YES,14,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.837,-3.807,1.97,,0.728,G,A,0.46,0.7,,,71.59,HHH,-1.82567,0.100394,0.00706614,0.805751 kka2_1:8_A14R,kka2_1:8_14,Kka2,kka2_1:8,P00552,,YES,14,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.837,-2.714,0.877,,0.728,G,A,0.46,0.7,,,71.59,HHH,-1.82567,0.100394,0.00706614,0.857147 kka2_1:8_A14R,kka2_1:8_14,Kka2,kka2_1:8,P00552,,YES,14,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.837,-2.714,0.877,,0.728,G,A,0.46,0.7,,,71.59,HHH,-1.82567,0.100394,0.00706614,0.857147 kka2_1:8_A150C,kka2_1:8_150,Kka2,kka2_1:8,P00552,,YES,150,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.949,-4.673,3.724,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.100394,0.0045009,0.713745 kka2_1:8_A150C,kka2_1:8_150,Kka2,kka2_1:8,P00552,,YES,150,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.949,-4.673,3.724,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.100394,0.0045009,0.713745 kka2_1:8_A150Y,kka2_1:8_150,Kka2,kka2_1:8,P00552,,YES,150,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.949,-4.269,3.32,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.100394,0.0045009,0.622011 kka2_1:8_A150Y,kka2_1:8_150,Kka2,kka2_1:8,P00552,,YES,150,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-0.949,-4.269,3.32,,0.544,T,A,0.46,1.34,1.656,,63.26,AHO,-1.272,0.100394,0.0045009,0.622011 kka2_1:8_A168I,kka2_1:8_168,Kka2,kka2_1:8,P00552,,YES,168,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.989,-4.068,2.079,,0.67,H,A,0.46,0.15,11.329,11.329,64.39,OHA,-2.12933,0.100394,0.00806773,0.772483 kka2_1:8_A168I,kka2_1:8_168,Kka2,kka2_1:8,P00552,,YES,168,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.989,-4.068,2.079,,0.67,H,A,0.46,0.15,11.329,11.329,64.39,OHA,-2.12933,0.100394,0.00806773,0.772483 kka2_1:8_A224C,kka2_1:8_224,Kka2,kka2_1:8,P00552,,YES,224,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.977,-4.591,3.614,,,H,A,0.46,-1.26,0.357,,63.64,HHP,-1.41033,0.100394,0.00352047,0.525347 kka2_1:8_A224C,kka2_1:8_224,Kka2,kka2_1:8,P00552,,YES,224,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-0.977,-4.591,3.614,,,H,A,0.46,-1.26,0.357,,63.64,HHP,-1.41033,0.100394,0.00352047,0.525347 kka2_1:8_A224I,kka2_1:8_224,Kka2,kka2_1:8,P00552,,YES,224,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.977,-3.567,2.59,,,H,A,0.46,-1.26,0.357,,63.64,HHP,-1.41033,0.100394,0.00352047,0.402913 kka2_1:8_A224I,kka2_1:8_224,Kka2,kka2_1:8,P00552,,YES,224,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.977,-3.567,2.59,,,H,A,0.46,-1.26,0.357,,63.64,HHP,-1.41033,0.100394,0.00352047,0.402913 kka2_1:8_A237F,kka2_1:8_237,Kka2,kka2_1:8,P00552,,YES,237,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.12,-4.013,1.893,,0.068,H,A,0.46,-0.71,0.449,,92.05,HHA,-2.10433,0.100394,0.012257,0.447948 kka2_1:8_A237F,kka2_1:8_237,Kka2,kka2_1:8,P00552,,YES,237,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.12,-4.013,1.893,,0.068,H,A,0.46,-0.71,0.449,,92.05,HHA,-2.10433,0.100394,0.012257,0.447948 kka2_1:8_A237H,kka2_1:8_237,Kka2,kka2_1:8,P00552,,YES,237,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.12,-4.997,2.877,,0.068,H,A,0.46,-0.71,0.449,,92.05,HHA,-2.10433,0.100394,0.012257,0.531633 kka2_1:8_A237H,kka2_1:8_237,Kka2,kka2_1:8,P00552,,YES,237,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.12,-4.997,2.877,,0.068,H,A,0.46,-0.71,0.449,,92.05,HHA,-2.10433,0.100394,0.012257,0.531633 kka2_1:8_A237Y,kka2_1:8_237,Kka2,kka2_1:8,P00552,,YES,237,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.12,-4.178,2.058,,0.068,H,A,0.46,-0.71,0.449,,92.05,HHA,-2.10433,0.100394,0.012257,0.462529 kka2_1:8_A237Y,kka2_1:8_237,Kka2,kka2_1:8,P00552,,YES,237,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.12,-4.178,2.058,,0.068,H,A,0.46,-0.71,0.449,,92.05,HHA,-2.10433,0.100394,0.012257,0.462529 kka2_1:8_A247F,kka2_1:8_247,Kka2,kka2_1:8,P00552,,YES,247,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.459,-3.316,0.857,,1.01,S,A,0.46,0.65,18.904,18.904,92.05,HHH,-2.197,0.100394,0.0102428,0.919485 kka2_1:8_A247F,kka2_1:8_247,Kka2,kka2_1:8,P00552,,YES,247,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.459,-3.316,0.857,,1.01,S,A,0.46,0.65,18.904,18.904,92.05,HHH,-2.197,0.100394,0.0102428,0.919485 kka2_1:8_A247H,kka2_1:8_247,Kka2,kka2_1:8,P00552,,YES,247,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.459,-3.473,1.014,,1.01,S,A,0.46,0.65,18.904,18.904,92.05,HHH,-2.197,0.100394,0.0102428,0.922864 kka2_1:8_A247H,kka2_1:8_247,Kka2,kka2_1:8,P00552,,YES,247,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.459,-3.473,1.014,,1.01,S,A,0.46,0.65,18.904,18.904,92.05,HHH,-2.197,0.100394,0.0102428,0.922864 kka2_1:8_A248C,kka2_1:8_248,Kka2,kka2_1:8,P00552,,YES,248,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.124,-5.173,3.049,,0.825,S,b,1.04,0.46,11.329,11.329,92.05,HHO,-2.15,0.100394,0.0125484,0.856656 kka2_1:8_A248C,kka2_1:8_248,Kka2,kka2_1:8,P00552,,YES,248,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-2.124,-5.173,3.049,,0.825,S,b,1.04,0.46,11.329,11.329,92.05,HHO,-2.15,0.100394,0.0125484,0.856656 kka2_1:8_A248F,kka2_1:8_248,Kka2,kka2_1:8,P00552,,YES,248,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.124,-4.425,2.301,,0.825,S,b,1.04,0.46,11.329,11.329,92.05,HHO,-2.15,0.100394,0.0125484,0.885693 kka2_1:8_A248F,kka2_1:8_248,Kka2,kka2_1:8,P00552,,YES,248,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.124,-4.425,2.301,,0.825,S,b,1.04,0.46,11.329,11.329,92.05,HHO,-2.15,0.100394,0.0125484,0.885693 kka2_1:8_A248H,kka2_1:8_248,Kka2,kka2_1:8,P00552,,YES,248,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.124,-3.589,1.465,,0.825,S,b,1.04,0.46,11.329,11.329,92.05,HHO,-2.15,0.100394,0.0125484,0.882515 kka2_1:8_A248H,kka2_1:8_248,Kka2,kka2_1:8,P00552,,YES,248,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.124,-3.589,1.465,,0.825,S,b,1.04,0.46,11.329,11.329,92.05,HHO,-2.15,0.100394,0.0125484,0.882515 kka2_1:8_A248I,kka2_1:8_248,Kka2,kka2_1:8,P00552,,YES,248,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.124,-3.04,0.916,,0.825,S,b,1.04,0.46,11.329,11.329,92.05,HHO,-2.15,0.100394,0.0125484,0.868176 kka2_1:8_A248I,kka2_1:8_248,Kka2,kka2_1:8,P00552,,YES,248,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.124,-3.04,0.916,,0.825,S,b,1.04,0.46,11.329,11.329,92.05,HHO,-2.15,0.100394,0.0125484,0.868176 kka2_1:8_A248N,kka2_1:8_248,Kka2,kka2_1:8,P00552,,YES,248,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.124,-3.883,1.759,,0.825,S,b,1.04,0.46,11.329,11.329,92.05,HHO,-2.15,0.100394,0.0125484,0.835949 kka2_1:8_A248N,kka2_1:8_248,Kka2,kka2_1:8,P00552,,YES,248,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.124,-3.883,1.759,,0.825,S,b,1.04,0.46,11.329,11.329,92.05,HHO,-2.15,0.100394,0.0125484,0.835949 kka2_1:8_A248Q,kka2_1:8_248,Kka2,kka2_1:8,P00552,,YES,248,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.124,-2.728,0.604,,0.825,S,b,1.04,0.46,11.329,11.329,92.05,HHO,-2.15,0.100394,0.0125484,0.894075 kka2_1:8_A248Q,kka2_1:8_248,Kka2,kka2_1:8,P00552,,YES,248,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-2.124,-2.728,0.604,,0.825,S,b,1.04,0.46,11.329,11.329,92.05,HHO,-2.15,0.100394,0.0125484,0.894075 kka2_1:8_A248Y,kka2_1:8_248,Kka2,kka2_1:8,P00552,,YES,248,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.124,-4.406,2.282,,0.825,S,b,1.04,0.46,11.329,11.329,92.05,HHO,-2.15,0.100394,0.0125484,0.905047 kka2_1:8_A248Y,kka2_1:8_248,Kka2,kka2_1:8,P00552,,YES,248,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.124,-4.406,2.282,,0.825,S,b,1.04,0.46,11.329,11.329,92.05,HHO,-2.15,0.100394,0.0125484,0.905047 kka2_1:8_A25I,kka2_1:8_25,Kka2,kka2_1:8,P00552,,YES,25,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.496,-3.984,1.488,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.100394,0.00595636,0.606972 kka2_1:8_A25I,kka2_1:8_25,Kka2,kka2_1:8,P00552,,YES,25,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.496,-3.984,1.488,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.100394,0.00595636,0.606972 kka2_1:8_A25K,kka2_1:8_25,Kka2,kka2_1:8,P00552,,YES,25,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.496,-2.905,0.409,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.100394,0.00595636,0.766922 kka2_1:8_A25K,kka2_1:8_25,Kka2,kka2_1:8,P00552,,YES,25,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.496,-2.905,0.409,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.100394,0.00595636,0.766922 kka2_1:8_A25Y,kka2_1:8_25,Kka2,kka2_1:8,P00552,,YES,25,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.496,-4.311,1.815,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.100394,0.00595636,0.647616 kka2_1:8_A25Y,kka2_1:8_25,Kka2,kka2_1:8,P00552,,YES,25,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.496,-4.311,1.815,,0.427,E,B,0.46,-0.47,1.689,,65.53,HHP,-2.15167,0.100394,0.00595636,0.647616 kka2_1:8_A34H,kka2_1:8_34,Kka2,kka2_1:8,P00552,,YES,34,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.928,-4.681,3.753,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.100394,0.00343484,0.464809 kka2_1:8_A34H,kka2_1:8_34,Kka2,kka2_1:8,P00552,,YES,34,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-0.928,-4.681,3.753,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.100394,0.00343484,0.464809 kka2_1:8_A34I,kka2_1:8_34,Kka2,kka2_1:8,P00552,,YES,34,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.928,-3.671,2.743,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.100394,0.00343484,0.435225 kka2_1:8_A34I,kka2_1:8_34,Kka2,kka2_1:8,P00552,,YES,34,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-0.928,-3.671,2.743,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.100394,0.00343484,0.435225 kka2_1:8_A34K,kka2_1:8_34,Kka2,kka2_1:8,P00552,,YES,34,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.928,-3.458,2.53,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.100394,0.00343484,0.479066 kka2_1:8_A34K,kka2_1:8_34,Kka2,kka2_1:8,P00552,,YES,34,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-0.928,-3.458,2.53,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.100394,0.00343484,0.479066 kka2_1:8_A34N,kka2_1:8_34,Kka2,kka2_1:8,P00552,,YES,34,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.928,-3.748,2.82,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.100394,0.00343484,0.436696 kka2_1:8_A34N,kka2_1:8_34,Kka2,kka2_1:8,P00552,,YES,34,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-0.928,-3.748,2.82,,0.417,,B,1.04,2.29,0.941,,52.27,AHH,-1.747,0.100394,0.00343484,0.436696 kka2_1:8_A35F,kka2_1:8_35,Kka2,kka2_1:8,P00552,,YES,35,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.127,-4.402,2.275,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.100394,0.00630016,0.653172 kka2_1:8_A35F,kka2_1:8_35,Kka2,kka2_1:8,P00552,,YES,35,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-2.127,-4.402,2.275,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.100394,0.00630016,0.653172 kka2_1:8_A35H,kka2_1:8_35,Kka2,kka2_1:8,P00552,,YES,35,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.127,-3.517,1.39,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.100394,0.00630016,0.674501 kka2_1:8_A35H,kka2_1:8_35,Kka2,kka2_1:8,P00552,,YES,35,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.127,-3.517,1.39,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.100394,0.00630016,0.674501 kka2_1:8_A35I,kka2_1:8_35,Kka2,kka2_1:8,P00552,,YES,35,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.127,-4.036,1.909,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.100394,0.00630016,0.653329 kka2_1:8_A35I,kka2_1:8_35,Kka2,kka2_1:8,P00552,,YES,35,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-2.127,-4.036,1.909,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.100394,0.00630016,0.653329 kka2_1:8_A35N,kka2_1:8_35,Kka2,kka2_1:8,P00552,,YES,35,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.127,-2.713,0.586,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.100394,0.00630016,0.762294 kka2_1:8_A35N,kka2_1:8_35,Kka2,kka2_1:8,P00552,,YES,35,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-2.127,-2.713,0.586,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.100394,0.00630016,0.762294 kka2_1:8_A35R,kka2_1:8_35,Kka2,kka2_1:8,P00552,,YES,35,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.127,-3.236,1.109,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.100394,0.00630016,0.695955 kka2_1:8_A35R,kka2_1:8_35,Kka2,kka2_1:8,P00552,,YES,35,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-2.127,-3.236,1.109,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.100394,0.00630016,0.695955 kka2_1:8_A35Y,kka2_1:8_35,Kka2,kka2_1:8,P00552,,YES,35,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.127,-4.416,2.289,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.100394,0.00630016,0.66253 kka2_1:8_A35Y,kka2_1:8_35,Kka2,kka2_1:8,P00552,,YES,35,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.127,-4.416,2.289,,0.107,E,B,0.46,1.05,2.084,,71.59,HHH,-1.31767,0.100394,0.00630016,0.66253 kka2_1:8_A41K,kka2_1:8_41,Kka2,kka2_1:8,P00552,,YES,41,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.879,-3.682,1.803,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.100394,0.00543332,0.577081 kka2_1:8_A41K,kka2_1:8_41,Kka2,kka2_1:8,P00552,,YES,41,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.879,-3.682,1.803,,0.184,.,B,0.46,-0.96,24.924,24.924,64.39,PHP,-2.477,0.100394,0.00543332,0.577081 kka2_1:8_A56K,kka2_1:8_56,Kka2,kka2_1:8,P00552,,YES,56,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.083,-3.671,1.588,,0.796,T,A,0.46,1.39,10.511,,71.59,OHH,-1.86867,0.100394,0.00717715,0.85985 kka2_1:8_A56K,kka2_1:8_56,Kka2,kka2_1:8,P00552,,YES,56,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.083,-3.671,1.588,,0.796,T,A,0.46,1.39,10.511,,71.59,OHH,-1.86867,0.100394,0.00717715,0.85985 kka2_1:8_A56Y,kka2_1:8_56,Kka2,kka2_1:8,P00552,,YES,56,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.083,-4.486,2.403,,0.796,T,A,0.46,1.39,10.511,,71.59,OHH,-1.86867,0.100394,0.00717715,0.896862 kka2_1:8_A56Y,kka2_1:8_56,Kka2,kka2_1:8,P00552,,YES,56,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-2.083,-4.486,2.403,,0.796,T,A,0.46,1.39,10.511,,71.59,OHH,-1.86867,0.100394,0.00717715,0.896862 kka2_1:8_A64F,kka2_1:8_64,Kka2,kka2_1:8,P00552,,YES,64,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.496,-4.09,2.594,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.100394,0.00705578,0.485635 kka2_1:8_A64F,kka2_1:8_64,Kka2,kka2_1:8,P00552,,YES,64,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.496,-4.09,2.594,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.100394,0.00705578,0.485635 kka2_1:8_A64I,kka2_1:8_64,Kka2,kka2_1:8,P00552,,YES,64,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.496,-1.939,0.443,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.100394,0.00705578,0.637201 kka2_1:8_A64I,kka2_1:8_64,Kka2,kka2_1:8,P00552,,YES,64,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.496,-1.939,0.443,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.100394,0.00705578,0.637201 kka2_1:8_A64Q,kka2_1:8_64,Kka2,kka2_1:8,P00552,,YES,64,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.496,-4.195,2.699,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.100394,0.00705578,0.500513 kka2_1:8_A64Q,kka2_1:8_64,Kka2,kka2_1:8,P00552,,YES,64,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.496,-4.195,2.699,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.100394,0.00705578,0.500513 kka2_1:8_A64W,kka2_1:8_64,Kka2,kka2_1:8,P00552,,YES,64,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.496,-5.479,3.983,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.100394,0.00705578,0.471532 kka2_1:8_A64W,kka2_1:8_64,Kka2,kka2_1:8,P00552,,YES,64,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.496,-5.479,3.983,,0.039,H,A,0.46,-0.57,4.354,,56.06,AHH,-1.334,0.100394,0.00705578,0.471532 kka2_1:8_A65D,kka2_1:8_65,Kka2,kka2_1:8,P00552,,YES,65,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.744,-2.659,0.915,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.100394,0.00709258,0.657591 kka2_1:8_A65D,kka2_1:8_65,Kka2,kka2_1:8,P00552,,YES,65,A,D,AD,Hydrophobic,negativeCharge,6,5.0516,-0.9484,126,89,133,44,88.6,111.1,22.5,-1.744,-2.659,0.915,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.100394,0.00709258,0.657591 kka2_1:8_A65H,kka2_1:8_65,Kka2,kka2_1:8,P00552,,YES,65,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.744,-3.525,1.781,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.100394,0.00709258,0.64958 kka2_1:8_A65H,kka2_1:8_65,Kka2,kka2_1:8,P00552,,YES,65,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.744,-3.525,1.781,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.100394,0.00709258,0.64958 kka2_1:8_A65I,kka2_1:8_65,Kka2,kka2_1:8,P00552,,YES,65,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.744,-3.823,2.079,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.100394,0.00709258,0.61965 kka2_1:8_A65I,kka2_1:8_65,Kka2,kka2_1:8,P00552,,YES,65,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.744,-3.823,2.079,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.100394,0.00709258,0.61965 kka2_1:8_A65N,kka2_1:8_65,Kka2,kka2_1:8,P00552,,YES,65,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.744,-3.167,1.423,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.100394,0.00709258,0.647896 kka2_1:8_A65N,kka2_1:8_65,Kka2,kka2_1:8,P00552,,YES,65,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.744,-3.167,1.423,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.100394,0.00709258,0.647896 kka2_1:8_A65R,kka2_1:8_65,Kka2,kka2_1:8,P00552,,YES,65,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.744,-3.924,2.18,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.100394,0.00709258,0.686498 kka2_1:8_A65R,kka2_1:8_65,Kka2,kka2_1:8,P00552,,YES,65,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.744,-3.924,2.18,,0.437,H,A,0.46,-0.39,1.445,,63.64,HHB,-1.38733,0.100394,0.00709258,0.686498 kka2_1:8_A71F,kka2_1:8_71,Kka2,kka2_1:8,P00552,,YES,71,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.824,-4.432,2.608,,0.553,H,A,0.46,0.08,18.64,18.64,64.39,HHP,-1.74033,0.100394,0.00727707,0.716324 kka2_1:8_A71F,kka2_1:8_71,Kka2,kka2_1:8,P00552,,YES,71,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.824,-4.432,2.608,,0.553,H,A,0.46,0.08,18.64,18.64,64.39,HHP,-1.74033,0.100394,0.00727707,0.716324 kka2_1:8_A71K,kka2_1:8_71,Kka2,kka2_1:8,P00552,,YES,71,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.824,-2.499,0.675,,0.553,H,A,0.46,0.08,18.64,18.64,64.39,HHP,-1.74033,0.100394,0.00727707,0.801608 kka2_1:8_A71K,kka2_1:8_71,Kka2,kka2_1:8,P00552,,YES,71,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.824,-2.499,0.675,,0.553,H,A,0.46,0.08,18.64,18.64,64.39,HHP,-1.74033,0.100394,0.00727707,0.801608 kka2_1:8_A71P,kka2_1:8_71,Kka2,kka2_1:8,P00552,,YES,71,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.824,-4.026,2.202,,0.553,H,A,0.46,0.08,18.64,18.64,64.39,HHP,-1.74033,0.100394,0.00727707,0.622824 kka2_1:8_A71P,kka2_1:8_71,Kka2,kka2_1:8,P00552,,YES,71,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-1.824,-4.026,2.202,,0.553,H,A,0.46,0.08,18.64,18.64,64.39,HHP,-1.74033,0.100394,0.00727707,0.622824 kka2_1:8_A79P,kka2_1:8_79,Kka2,kka2_1:8,P00552,,YES,79,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.368,-3.3,0.932,,0.563,.,B,0.46,-0.43,,,71.59,HHH,-1.752,0.100394,0.00664821,0.823171 kka2_1:8_A79P,kka2_1:8_79,Kka2,kka2_1:8,P00552,,YES,79,A,P,AP,Hydrophobic,Special,6,6.3,0.3,27,89,115,26,88.6,112.7,24.1,-2.368,-3.3,0.932,,0.563,.,B,0.46,-0.43,,,71.59,HHH,-1.752,0.100394,0.00664821,0.823171 kka2_1:8_A87I,kka2_1:8_87,Kka2,kka2_1:8,P00552,,YES,87,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.917,-4.113,2.196,,1.039,S,L,0.46,1.57,16.115,16.115,65.53,AHO,-1.822,0.100394,0.00791281,0.73923 kka2_1:8_A87I,kka2_1:8_87,Kka2,kka2_1:8,P00552,,YES,87,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.917,-4.113,2.196,,1.039,S,L,0.46,1.57,16.115,16.115,65.53,AHO,-1.822,0.100394,0.00791281,0.73923 kka2_1:8_A87K,kka2_1:8_87,Kka2,kka2_1:8,P00552,,YES,87,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.917,-3.626,1.709,,1.039,S,L,0.46,1.57,16.115,16.115,65.53,AHO,-1.822,0.100394,0.00791281,0.804404 kka2_1:8_A87K,kka2_1:8_87,Kka2,kka2_1:8,P00552,,YES,87,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.917,-3.626,1.709,,1.039,S,L,0.46,1.57,16.115,16.115,65.53,AHO,-1.822,0.100394,0.00791281,0.804404 kka2_1:8_A87M,kka2_1:8_87,Kka2,kka2_1:8,P00552,,YES,87,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.917,-4.877,2.96,,1.039,S,L,0.46,1.57,16.115,16.115,65.53,AHO,-1.822,0.100394,0.00791281,0.808022 kka2_1:8_A87M,kka2_1:8_87,Kka2,kka2_1:8,P00552,,YES,87,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.917,-4.877,2.96,,1.039,S,L,0.46,1.57,16.115,16.115,65.53,AHO,-1.822,0.100394,0.00791281,0.808022 kka2_1:8_A87N,kka2_1:8_87,Kka2,kka2_1:8,P00552,,YES,87,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.917,-2.703,0.786,,1.039,S,L,0.46,1.57,16.115,16.115,65.53,AHO,-1.822,0.100394,0.00791281,0.828142 kka2_1:8_A87N,kka2_1:8_87,Kka2,kka2_1:8,P00552,,YES,87,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.917,-2.703,0.786,,1.039,S,L,0.46,1.57,16.115,16.115,65.53,AHO,-1.822,0.100394,0.00791281,0.828142 kka2_1:8_A87R,kka2_1:8_87,Kka2,kka2_1:8,P00552,,YES,87,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.917,-3.21,1.293,,1.039,S,L,0.46,1.57,16.115,16.115,65.53,AHO,-1.822,0.100394,0.00791281,0.830689 kka2_1:8_A87R,kka2_1:8_87,Kka2,kka2_1:8,P00552,,YES,87,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.917,-3.21,1.293,,1.039,S,L,0.46,1.57,16.115,16.115,65.53,AHO,-1.822,0.100394,0.00791281,0.830689 kka2_1:8_A87W,kka2_1:8_87,Kka2,kka2_1:8,P00552,,YES,87,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.917,-5.563,3.646,,1.039,S,L,0.46,1.57,16.115,16.115,65.53,AHO,-1.822,0.100394,0.00791281,0.748718 kka2_1:8_A87W,kka2_1:8_87,Kka2,kka2_1:8,P00552,,YES,87,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.917,-5.563,3.646,,1.039,S,L,0.46,1.57,16.115,16.115,65.53,AHO,-1.822,0.100394,0.00791281,0.748718 kka2_1:8_A87Y,kka2_1:8_87,Kka2,kka2_1:8,P00552,,YES,87,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.917,-4.401,2.484,,1.039,S,L,0.46,1.57,16.115,16.115,65.53,AHO,-1.822,0.100394,0.00791281,0.7926 kka2_1:8_A87Y,kka2_1:8_87,Kka2,kka2_1:8,P00552,,YES,87,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.917,-4.401,2.484,,1.039,S,L,0.46,1.57,16.115,16.115,65.53,AHO,-1.822,0.100394,0.00791281,0.7926 kka2_1:8_A9H,kka2_1:8_9,Kka2,kka2_1:8,P00552,,YES,9,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.079,-4.629,2.55,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.100394,0.00273264,0.915051 kka2_1:8_A9H,kka2_1:8_9,Kka2,kka2_1:8,P00552,,YES,9,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-2.079,-4.629,2.55,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.100394,0.00273264,0.915051 kka2_1:8_A9K,kka2_1:8_9,Kka2,kka2_1:8,P00552,,YES,9,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.079,-3.506,1.427,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.100394,0.00273264,0.921906 kka2_1:8_A9K,kka2_1:8_9,Kka2,kka2_1:8,P00552,,YES,9,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-2.079,-3.506,1.427,,,,,,,11.413,11.413,71.59,BHO,-2.253,0.100394,0.00273264,0.921906 kka2_1:8_C131A,kka2_1:8_131,Kka2,kka2_1:8,P00552,,YES,131,C,A,CA,Special,Hydrophobic,5.07,6,0.93,195,121,89,-32,108.5,88.6,-19.9,-0.831,-2.881,2.05,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.100394,0.00170814,0.484594 kka2_1:8_C131A,kka2_1:8_131,Kka2,kka2_1:8,P00552,,YES,131,C,A,CA,Special,Hydrophobic,5.07,6,0.93,195,121,89,-32,108.5,88.6,-19.9,-0.831,-2.881,2.05,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.100394,0.00170814,0.484594 kka2_1:8_C131D,kka2_1:8_131,Kka2,kka2_1:8,P00552,,YES,131,C,D,CD,Special,negativeCharge,5.07,5.0516,-0.0184,154,121,133,12,108.5,111.1,2.6,-0.831,-3.947,3.116,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.100394,0.00170814,0.449708 kka2_1:8_C131D,kka2_1:8_131,Kka2,kka2_1:8,P00552,,YES,131,C,D,CD,Special,negativeCharge,5.07,5.0516,-0.0184,154,121,133,12,108.5,111.1,2.6,-0.831,-3.947,3.116,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.100394,0.00170814,0.449708 kka2_1:8_C131E,kka2_1:8_131,Kka2,kka2_1:8,P00552,,YES,131,C,E,CE,Special,negativeCharge,5.07,3.22,-1.85,170,121,147,26,108.5,138.4,29.9,-0.831,-4.143,3.312,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.100394,0.00170814,0.440501 kka2_1:8_C131E,kka2_1:8_131,Kka2,kka2_1:8,P00552,,YES,131,C,E,CE,Special,negativeCharge,5.07,3.22,-1.85,170,121,147,26,108.5,138.4,29.9,-0.831,-4.143,3.312,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.100394,0.00170814,0.440501 kka2_1:8_C131H,kka2_1:8_131,Kka2,kka2_1:8,P00552,,YES,131,C,H,CH,Special,PositiveCharge,5.07,7.59,2.52,174,121,155,34,108.5,153.2,44.7,-0.831,-4.933,4.102,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.100394,0.00170814,0.428069 kka2_1:8_C131H,kka2_1:8_131,Kka2,kka2_1:8,P00552,,YES,131,C,H,CH,Special,PositiveCharge,5.07,7.59,2.52,174,121,155,34,108.5,153.2,44.7,-0.831,-4.933,4.102,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.100394,0.00170814,0.428069 kka2_1:8_C131I,kka2_1:8_131,Kka2,kka2_1:8,P00552,,YES,131,C,I,CI,Special,Hydrophobic,5.07,6.02,0.95,198,121,131,10,108.5,166.7,58.2,-0.831,-3.589,2.758,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.100394,0.00170814,0.451677 kka2_1:8_C131I,kka2_1:8_131,Kka2,kka2_1:8,P00552,,YES,131,C,I,CI,Special,Hydrophobic,5.07,6.02,0.95,198,121,131,10,108.5,166.7,58.2,-0.831,-3.589,2.758,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.100394,0.00170814,0.451677 kka2_1:8_C131K,kka2_1:8_131,Kka2,kka2_1:8,P00552,,YES,131,C,K,CK,Special,PositiveCharge,5.07,9.74,4.67,202,121,146,25,108.5,168.6,60.1,-0.831,-3.935,3.104,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.100394,0.00170814,0.458796 kka2_1:8_C131K,kka2_1:8_131,Kka2,kka2_1:8,P00552,,YES,131,C,K,CK,Special,PositiveCharge,5.07,9.74,4.67,202,121,146,25,108.5,168.6,60.1,-0.831,-3.935,3.104,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.100394,0.00170814,0.458796 kka2_1:8_C131M,kka2_1:8_131,Kka2,kka2_1:8,P00552,,YES,131,C,M,CM,Special,Hydrophobic,5.07,5.74,0.67,196,121,149,28,108.5,162.9,54.4,-0.831,-4.508,3.677,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.100394,0.00170814,0.446769 kka2_1:8_C131M,kka2_1:8_131,Kka2,kka2_1:8,P00552,,YES,131,C,M,CM,Special,Hydrophobic,5.07,5.74,0.67,196,121,149,28,108.5,162.9,54.4,-0.831,-4.508,3.677,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.100394,0.00170814,0.446769 kka2_1:8_C131P,kka2_1:8_131,Kka2,kka2_1:8,P00552,,YES,131,C,P,CP,Special,Special,5.07,6.3,1.23,169,121,115,-6,108.5,112.7,4.2,-0.831,-4.133,3.302,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.100394,0.00170814,0.460115 kka2_1:8_C131P,kka2_1:8_131,Kka2,kka2_1:8,P00552,,YES,131,C,P,CP,Special,Special,5.07,6.3,1.23,169,121,115,-6,108.5,112.7,4.2,-0.831,-4.133,3.302,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.100394,0.00170814,0.460115 kka2_1:8_C131Q,kka2_1:8_131,Kka2,kka2_1:8,P00552,,YES,131,C,Q,CQ,Special,Polar,5.07,6.24429,1.17429,154,121,146,25,108.5,143.8,35.3,-0.831,-4.378,3.547,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.100394,0.00170814,0.43785 kka2_1:8_C131Q,kka2_1:8_131,Kka2,kka2_1:8,P00552,,YES,131,C,Q,CQ,Special,Polar,5.07,6.24429,1.17429,154,121,146,25,108.5,143.8,35.3,-0.831,-4.378,3.547,,0.124,.,B,0.46,0.48,,,,POO,-1.33267,0.100394,0.00170814,0.43785 kka2_1:8_C31A,kka2_1:8_31,Kka2,kka2_1:8,P00552,,YES,31,C,A,CA,Special,Hydrophobic,5.07,6,0.93,195,121,89,-32,108.5,88.6,-19.9,-2.246,-2.378,0.132,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.100394,0.00681582,0.829941 kka2_1:8_C31A,kka2_1:8_31,Kka2,kka2_1:8,P00552,,YES,31,C,A,CA,Special,Hydrophobic,5.07,6,0.93,195,121,89,-32,108.5,88.6,-19.9,-2.246,-2.378,0.132,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.100394,0.00681582,0.829941 kka2_1:8_C31D,kka2_1:8_31,Kka2,kka2_1:8,P00552,,YES,31,C,D,CD,Special,negativeCharge,5.07,5.0516,-0.0184,154,121,133,12,108.5,111.1,2.6,-2.246,-3.622,1.376,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.100394,0.00681582,0.676851 kka2_1:8_C31D,kka2_1:8_31,Kka2,kka2_1:8,P00552,,YES,31,C,D,CD,Special,negativeCharge,5.07,5.0516,-0.0184,154,121,133,12,108.5,111.1,2.6,-2.246,-3.622,1.376,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.100394,0.00681582,0.676851 kka2_1:8_C31H,kka2_1:8_31,Kka2,kka2_1:8,P00552,,YES,31,C,H,CH,Special,PositiveCharge,5.07,7.59,2.52,174,121,155,34,108.5,153.2,44.7,-2.246,-3.333,1.087,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.100394,0.00681582,0.767785 kka2_1:8_C31H,kka2_1:8_31,Kka2,kka2_1:8,P00552,,YES,31,C,H,CH,Special,PositiveCharge,5.07,7.59,2.52,174,121,155,34,108.5,153.2,44.7,-2.246,-3.333,1.087,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.100394,0.00681582,0.767785 kka2_1:8_C31M,kka2_1:8_31,Kka2,kka2_1:8,P00552,,YES,31,C,M,CM,Special,Hydrophobic,5.07,5.74,0.67,196,121,149,28,108.5,162.9,54.4,-2.246,-4.677,2.431,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.100394,0.00681582,0.666908 kka2_1:8_C31M,kka2_1:8_31,Kka2,kka2_1:8,P00552,,YES,31,C,M,CM,Special,Hydrophobic,5.07,5.74,0.67,196,121,149,28,108.5,162.9,54.4,-2.246,-4.677,2.431,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.100394,0.00681582,0.666908 kka2_1:8_C31P,kka2_1:8_31,Kka2,kka2_1:8,P00552,,YES,31,C,P,CP,Special,Special,5.07,6.3,1.23,169,121,115,-6,108.5,112.7,4.2,-2.246,-4.029,1.783,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.100394,0.00681582,0.577649 kka2_1:8_C31P,kka2_1:8_31,Kka2,kka2_1:8,P00552,,YES,31,C,P,CP,Special,Special,5.07,6.3,1.23,169,121,115,-6,108.5,112.7,4.2,-2.246,-4.029,1.783,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.100394,0.00681582,0.577649 kka2_1:8_C31Q,kka2_1:8_31,Kka2,kka2_1:8,P00552,,YES,31,C,Q,CQ,Special,Polar,5.07,6.24429,1.17429,154,121,146,25,108.5,143.8,35.3,-2.246,-2.477,0.231,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.100394,0.00681582,0.807346 kka2_1:8_C31Q,kka2_1:8_31,Kka2,kka2_1:8,P00552,,YES,31,C,Q,CQ,Special,Polar,5.07,6.24429,1.17429,154,121,146,25,108.5,143.8,35.3,-2.246,-2.477,0.231,,1.152,S,b,1.5,4.16,8.272,,63.26,OOP,-1.21533,0.100394,0.00681582,0.807346 kka2_1:8_D101L,kka2_1:8_101,Kka2,kka2_1:8,P00552,,YES,101,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.028,-3.645,2.617,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.100394,0.00423361,0.459867 kka2_1:8_D101L,kka2_1:8_101,Kka2,kka2_1:8,P00552,,YES,101,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.028,-3.645,2.617,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.100394,0.00423361,0.459867 kka2_1:8_D101M,kka2_1:8_101,Kka2,kka2_1:8,P00552,,YES,101,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.028,-4.841,3.813,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.100394,0.00423361,0.457916 kka2_1:8_D101M,kka2_1:8_101,Kka2,kka2_1:8,P00552,,YES,101,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.028,-4.841,3.813,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.100394,0.00423361,0.457916 kka2_1:8_D101P,kka2_1:8_101,Kka2,kka2_1:8,P00552,,YES,101,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.028,-3.843,2.815,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.100394,0.00423361,0.470171 kka2_1:8_D101P,kka2_1:8_101,Kka2,kka2_1:8,P00552,,YES,101,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.028,-3.843,2.815,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.100394,0.00423361,0.470171 kka2_1:8_D101V,kka2_1:8_101,Kka2,kka2_1:8,P00552,,YES,101,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.028,-2.595,1.567,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.100394,0.00423361,0.597798 kka2_1:8_D101V,kka2_1:8_101,Kka2,kka2_1:8,P00552,,YES,101,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.028,-2.595,1.567,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.100394,0.00423361,0.597798 kka2_1:8_D101W,kka2_1:8_101,Kka2,kka2_1:8,P00552,,YES,101,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.028,-5.632,4.604,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.100394,0.00423361,0.426707 kka2_1:8_D101W,kka2_1:8_101,Kka2,kka2_1:8,P00552,,YES,101,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.028,-5.632,4.604,,0.213,E,B,0.29,-1.24,8.707,,63.64,PAH,-1.534,0.100394,0.00423361,0.426707 kka2_1:8_D118A,kka2_1:8_118,Kka2,kka2_1:8,P00552,,YES,118,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.07,-2.21,0.14,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.100394,0.0067852,0.769216 kka2_1:8_D118A,kka2_1:8_118,Kka2,kka2_1:8,P00552,,YES,118,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.07,-2.21,0.14,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.100394,0.0067852,0.769216 kka2_1:8_D118C,kka2_1:8_118,Kka2,kka2_1:8,P00552,,YES,118,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.07,-5.162,3.092,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.100394,0.0067852,0.706338 kka2_1:8_D118C,kka2_1:8_118,Kka2,kka2_1:8,P00552,,YES,118,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.07,-5.162,3.092,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.100394,0.0067852,0.706338 kka2_1:8_D118G,kka2_1:8_118,Kka2,kka2_1:8,P00552,,YES,118,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.07,-2.786,0.716,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.100394,0.0067852,0.679864 kka2_1:8_D118G,kka2_1:8_118,Kka2,kka2_1:8,P00552,,YES,118,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-2.07,-2.786,0.716,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.100394,0.0067852,0.679864 kka2_1:8_D118M,kka2_1:8_118,Kka2,kka2_1:8,P00552,,YES,118,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.07,-3.354,1.284,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.100394,0.0067852,0.644392 kka2_1:8_D118M,kka2_1:8_118,Kka2,kka2_1:8,P00552,,YES,118,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.07,-3.354,1.284,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.100394,0.0067852,0.644392 kka2_1:8_D118S,kka2_1:8_118,Kka2,kka2_1:8,P00552,,YES,118,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.07,-2.544,0.474,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.100394,0.0067852,0.72191 kka2_1:8_D118S,kka2_1:8_118,Kka2,kka2_1:8,P00552,,YES,118,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.07,-2.544,0.474,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.100394,0.0067852,0.72191 kka2_1:8_D118W,kka2_1:8_118,Kka2,kka2_1:8,P00552,,YES,118,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.07,-5.579,3.509,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.100394,0.0067852,0.612678 kka2_1:8_D118W,kka2_1:8_118,Kka2,kka2_1:8,P00552,,YES,118,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.07,-5.579,3.509,,0.61,H,A,0.75,-0.05,1.607,,64.39,HAH,-1.32367,0.100394,0.0067852,0.612678 kka2_1:8_D127C,kka2_1:8_127,Kka2,kka2_1:8,P00552,,YES,127,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.364,-5.181,3.817,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.100394,0.00660501,0.609851 kka2_1:8_D127C,kka2_1:8_127,Kka2,kka2_1:8,P00552,,YES,127,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.364,-5.181,3.817,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.100394,0.00660501,0.609851 kka2_1:8_D127K,kka2_1:8_127,Kka2,kka2_1:8,P00552,,YES,127,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.364,-3.534,2.17,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.100394,0.00660501,0.599103 kka2_1:8_D127K,kka2_1:8_127,Kka2,kka2_1:8,P00552,,YES,127,D,K,DK,negativeCharge,PositiveCharge,5.0516,9.74,4.6884,101,133,146,13,111.1,168.6,57.5,-1.364,-3.534,2.17,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.100394,0.00660501,0.599103 kka2_1:8_D127L,kka2_1:8_127,Kka2,kka2_1:8,P00552,,YES,127,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.364,-3.769,2.405,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.100394,0.00660501,0.550601 kka2_1:8_D127L,kka2_1:8_127,Kka2,kka2_1:8,P00552,,YES,127,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.364,-3.769,2.405,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.100394,0.00660501,0.550601 kka2_1:8_D127M,kka2_1:8_127,Kka2,kka2_1:8,P00552,,YES,127,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.364,-4.921,3.557,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.100394,0.00660501,0.537531 kka2_1:8_D127M,kka2_1:8_127,Kka2,kka2_1:8,P00552,,YES,127,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.364,-4.921,3.557,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.100394,0.00660501,0.537531 kka2_1:8_D127P,kka2_1:8_127,Kka2,kka2_1:8,P00552,,YES,127,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.364,-1.54,0.176,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.100394,0.00660501,0.735795 kka2_1:8_D127P,kka2_1:8_127,Kka2,kka2_1:8,P00552,,YES,127,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.364,-1.54,0.176,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.100394,0.00660501,0.735795 kka2_1:8_D127S,kka2_1:8_127,Kka2,kka2_1:8,P00552,,YES,127,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.364,-3.391,2.027,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.100394,0.00660501,0.607125 kka2_1:8_D127S,kka2_1:8_127,Kka2,kka2_1:8,P00552,,YES,127,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.364,-3.391,2.027,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.100394,0.00660501,0.607125 kka2_1:8_D127T,kka2_1:8_127,Kka2,kka2_1:8,P00552,,YES,127,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.364,-3.566,2.202,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.100394,0.00660501,0.616864 kka2_1:8_D127T,kka2_1:8_127,Kka2,kka2_1:8,P00552,,YES,127,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.364,-3.566,2.202,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.100394,0.00660501,0.616864 kka2_1:8_D127W,kka2_1:8_127,Kka2,kka2_1:8,P00552,,YES,127,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.364,-5.662,4.298,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.100394,0.00660501,0.50991 kka2_1:8_D127W,kka2_1:8_127,Kka2,kka2_1:8,P00552,,YES,127,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.364,-5.662,4.298,,0.573,.,B,0.75,0.45,1.102,,50.38,HAO,-1.51067,0.100394,0.00660501,0.50991 kka2_1:8_D134W,kka2_1:8_134,Kka2,kka2_1:8,P00552,,YES,134,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.969,-5.579,4.61,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.100394,0.00270812,0.670629 kka2_1:8_D134W,kka2_1:8_134,Kka2,kka2_1:8,P00552,,YES,134,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.969,-5.579,4.61,,0.421,B,B,0.75,0.31,2.485,,49.62,HAB,-1.057,0.100394,0.00270812,0.670629 kka2_1:8_D154L,kka2_1:8_154,Kka2,kka2_1:8,P00552,,YES,154,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.876,-3.838,2.962,,0.457,,b,0.29,1.48,0.844,,52.65,HAP,-1.52467,0.100394,0.00292633,0.650576 kka2_1:8_D154L,kka2_1:8_154,Kka2,kka2_1:8,P00552,,YES,154,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.876,-3.838,2.962,,0.457,,b,0.29,1.48,0.844,,52.65,HAP,-1.52467,0.100394,0.00292633,0.650576 kka2_1:8_D154P,kka2_1:8_154,Kka2,kka2_1:8,P00552,,YES,154,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.876,-3.765,2.889,,0.457,,b,0.29,1.48,0.844,,52.65,HAP,-1.52467,0.100394,0.00292633,0.667811 kka2_1:8_D154P,kka2_1:8_154,Kka2,kka2_1:8,P00552,,YES,154,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.876,-3.765,2.889,,0.457,,b,0.29,1.48,0.844,,52.65,HAP,-1.52467,0.100394,0.00292633,0.667811 kka2_1:8_D154W,kka2_1:8_154,Kka2,kka2_1:8,P00552,,YES,154,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.876,-5.609,4.733,,0.457,,b,0.29,1.48,0.844,,52.65,HAP,-1.52467,0.100394,0.00292633,0.645087 kka2_1:8_D154W,kka2_1:8_154,Kka2,kka2_1:8,P00552,,YES,154,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.876,-5.609,4.733,,0.457,,b,0.29,1.48,0.844,,52.65,HAP,-1.52467,0.100394,0.00292633,0.645087 kka2_1:8_D156L,kka2_1:8_156,Kka2,kka2_1:8,P00552,,YES,156,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.696,-3.635,1.939,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.100394,0.00926998,0.79549 kka2_1:8_D156L,kka2_1:8_156,Kka2,kka2_1:8,P00552,,YES,156,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.696,-3.635,1.939,,0.884,T,A,0.29,1.87,2.789,,65.53,PAA,-1.765,0.100394,0.00926998,0.79549 kka2_1:8_D157L,kka2_1:8_157,Kka2,kka2_1:8,P00552,,YES,157,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.993,-3.843,2.85,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.100394,0.0042313,0.59214 kka2_1:8_D157L,kka2_1:8_157,Kka2,kka2_1:8,P00552,,YES,157,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-0.993,-3.843,2.85,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.100394,0.0042313,0.59214 kka2_1:8_D157M,kka2_1:8_157,Kka2,kka2_1:8,P00552,,YES,157,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.993,-4.965,3.972,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.100394,0.0042313,0.635357 kka2_1:8_D157M,kka2_1:8_157,Kka2,kka2_1:8,P00552,,YES,157,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.993,-4.965,3.972,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.100394,0.0042313,0.635357 kka2_1:8_D157P,kka2_1:8_157,Kka2,kka2_1:8,P00552,,YES,157,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.993,-3.813,2.82,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.100394,0.0042313,0.608318 kka2_1:8_D157P,kka2_1:8_157,Kka2,kka2_1:8,P00552,,YES,157,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.993,-3.813,2.82,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.100394,0.0042313,0.608318 kka2_1:8_D157W,kka2_1:8_157,Kka2,kka2_1:8,P00552,,YES,157,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.993,-5.591,4.598,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.100394,0.0042313,0.628696 kka2_1:8_D157W,kka2_1:8_157,Kka2,kka2_1:8,P00552,,YES,157,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.993,-5.591,4.598,,0.726,S,a,0.29,1.28,1.471,,65.53,AAH,-1.54533,0.100394,0.0042313,0.628696 kka2_1:8_D159S,kka2_1:8_159,Kka2,kka2_1:8,P00552,,YES,159,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.82,-3.223,2.403,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.100394,0.0030485,0.53875 kka2_1:8_D159S,kka2_1:8_159,Kka2,kka2_1:8,P00552,,YES,159,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.82,-3.223,2.403,,0.28,.,B,0.75,1.25,1.647,,48.11,HAA,-1.48333,0.100394,0.0030485,0.53875 kka2_1:8_D180A,kka2_1:8_180,Kka2,kka2_1:8,P00552,,YES,180,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.416,-2.13,-0.286,,1.03,S,a,0.75,1.5,14.668,14.668,71.59,OAO,-2.02933,0.100394,0.00756412,0.97121 kka2_1:8_D180A,kka2_1:8_180,Kka2,kka2_1:8,P00552,,YES,180,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-2.416,-2.13,-0.286,,1.03,S,a,0.75,1.5,14.668,14.668,71.59,OAO,-2.02933,0.100394,0.00756412,0.97121 kka2_1:8_D180L,kka2_1:8_180,Kka2,kka2_1:8,P00552,,YES,180,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.416,-2.808,0.392,,1.03,S,a,0.75,1.5,14.668,14.668,71.59,OAO,-2.02933,0.100394,0.00756412,0.894336 kka2_1:8_D180L,kka2_1:8_180,Kka2,kka2_1:8,P00552,,YES,180,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.416,-2.808,0.392,,1.03,S,a,0.75,1.5,14.668,14.668,71.59,OAO,-2.02933,0.100394,0.00756412,0.894336 kka2_1:8_D180M,kka2_1:8_180,Kka2,kka2_1:8,P00552,,YES,180,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.416,-3.738,1.322,,1.03,S,a,0.75,1.5,14.668,14.668,71.59,OAO,-2.02933,0.100394,0.00756412,0.901938 kka2_1:8_D180M,kka2_1:8_180,Kka2,kka2_1:8,P00552,,YES,180,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.416,-3.738,1.322,,1.03,S,a,0.75,1.5,14.668,14.668,71.59,OAO,-2.02933,0.100394,0.00756412,0.901938 kka2_1:8_D180P,kka2_1:8_180,Kka2,kka2_1:8,P00552,,YES,180,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.416,-3.147,0.731,,1.03,S,a,0.75,1.5,14.668,14.668,71.59,OAO,-2.02933,0.100394,0.00756412,0.852576 kka2_1:8_D180P,kka2_1:8_180,Kka2,kka2_1:8,P00552,,YES,180,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.416,-3.147,0.731,,1.03,S,a,0.75,1.5,14.668,14.668,71.59,OAO,-2.02933,0.100394,0.00756412,0.852576 kka2_1:8_D190W,kka2_1:8_190,Kka2,kka2_1:8,P00552,,YES,190,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.708,-5.576,4.868,,0.213,S,b,0.29,-0.82,,,,OAH,-0.711667,0.100394,0.00247989,0.374445 kka2_1:8_D190W,kka2_1:8_190,Kka2,kka2_1:8,P00552,,YES,190,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.708,-5.576,4.868,,0.213,S,b,0.29,-0.82,,,,OAH,-0.711667,0.100394,0.00247989,0.374445 kka2_1:8_D216A,kka2_1:8_216,Kka2,kka2_1:8,P00552,,YES,216,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.785,-3.354,2.569,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.100394,0.00229969,0.490309 kka2_1:8_D216A,kka2_1:8_216,Kka2,kka2_1:8,P00552,,YES,216,D,A,DA,negativeCharge,Hydrophobic,5.0516,6,0.9484,126,133,89,-44,111.1,88.6,-22.5,-0.785,-3.354,2.569,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.100394,0.00229969,0.490309 kka2_1:8_D216C,kka2_1:8_216,Kka2,kka2_1:8,P00552,,YES,216,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.785,-5.139,4.354,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.100394,0.00229969,0.505588 kka2_1:8_D216C,kka2_1:8_216,Kka2,kka2_1:8,P00552,,YES,216,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-0.785,-5.139,4.354,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.100394,0.00229969,0.505588 kka2_1:8_D216G,kka2_1:8_216,Kka2,kka2_1:8,P00552,,YES,216,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.785,-3.205,2.42,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.100394,0.00229969,0.515617 kka2_1:8_D216G,kka2_1:8_216,Kka2,kka2_1:8,P00552,,YES,216,D,G,DG,negativeCharge,Special,5.0516,3.29388,-1.75772,94,133,75,-58,111.1,60.1,-51,-0.785,-3.205,2.42,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.100394,0.00229969,0.515617 kka2_1:8_D216P,kka2_1:8_216,Kka2,kka2_1:8,P00552,,YES,216,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.785,-3.727,2.942,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.100394,0.00229969,0.481343 kka2_1:8_D216P,kka2_1:8_216,Kka2,kka2_1:8,P00552,,YES,216,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-0.785,-3.727,2.942,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.100394,0.00229969,0.481343 kka2_1:8_D216S,kka2_1:8_216,Kka2,kka2_1:8,P00552,,YES,216,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.785,-3.233,2.448,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.100394,0.00229969,0.51275 kka2_1:8_D216S,kka2_1:8_216,Kka2,kka2_1:8,P00552,,YES,216,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-0.785,-3.233,2.448,,0.018,E,B,0.75,-0.51,0.428,,19.32,HAB,-0.970333,0.100394,0.00229969,0.51275 kka2_1:8_D227R,kka2_1:8_227,Kka2,kka2_1:8,P00552,,YES,227,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.758,-3.84,2.082,,0.128,H,A,0.75,-0.63,0.281,,56.06,BAH,-1.43067,0.100394,0.00745029,0.464999 kka2_1:8_D227R,kka2_1:8_227,Kka2,kka2_1:8,P00552,,YES,227,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.758,-3.84,2.082,,0.128,H,A,0.75,-0.63,0.281,,56.06,BAH,-1.43067,0.100394,0.00745029,0.464999 kka2_1:8_D238F,kka2_1:8_238,Kka2,kka2_1:8,P00552,,YES,238,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.83,-4.489,1.659,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.100394,0.0113863,0.927711 kka2_1:8_D238F,kka2_1:8_238,Kka2,kka2_1:8,P00552,,YES,238,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-2.83,-4.489,1.659,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.100394,0.0113863,0.927711 kka2_1:8_D238I,kka2_1:8_238,Kka2,kka2_1:8,P00552,,YES,238,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.83,-4.106,1.276,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.100394,0.0113863,0.903353 kka2_1:8_D238I,kka2_1:8_238,Kka2,kka2_1:8,P00552,,YES,238,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-2.83,-4.106,1.276,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.100394,0.0113863,0.903353 kka2_1:8_D238M,kka2_1:8_238,Kka2,kka2_1:8,P00552,,YES,238,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.83,-3.594,0.764,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.100394,0.0113863,0.932152 kka2_1:8_D238M,kka2_1:8_238,Kka2,kka2_1:8,P00552,,YES,238,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.83,-3.594,0.764,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.100394,0.0113863,0.932152 kka2_1:8_D238P,kka2_1:8_238,Kka2,kka2_1:8,P00552,,YES,238,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.83,-2.766,-0.064,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.100394,0.0113863,0.903409 kka2_1:8_D238P,kka2_1:8_238,Kka2,kka2_1:8,P00552,,YES,238,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.83,-2.766,-0.064,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.100394,0.0113863,0.903409 kka2_1:8_D238R,kka2_1:8_238,Kka2,kka2_1:8,P00552,,YES,238,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.83,-2.777,-0.053,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.100394,0.0113863,0.957221 kka2_1:8_D238R,kka2_1:8_238,Kka2,kka2_1:8,P00552,,YES,238,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.83,-2.777,-0.053,,0.604,H,A,0.75,-0.33,,,92.05,HAB,-2.633,0.100394,0.0113863,0.957221 kka2_1:8_D23P,kka2_1:8_23,Kka2,kka2_1:8,P00552,,YES,23,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.459,-3.293,0.834,,0.695,E,B,0.75,-0.65,,,65.53,HAH,-1.94033,0.100394,0.007195,0.826804 kka2_1:8_D23P,kka2_1:8_23,Kka2,kka2_1:8,P00552,,YES,23,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.459,-3.293,0.834,,0.695,E,B,0.75,-0.65,,,65.53,HAH,-1.94033,0.100394,0.007195,0.826804 kka2_1:8_D23W,kka2_1:8_23,Kka2,kka2_1:8,P00552,,YES,23,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.459,-5.599,3.14,,0.695,E,B,0.75,-0.65,,,65.53,HAH,-1.94033,0.100394,0.007195,0.765926 kka2_1:8_D23W,kka2_1:8_23,Kka2,kka2_1:8,P00552,,YES,23,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.459,-5.599,3.14,,0.695,E,B,0.75,-0.65,,,65.53,HAH,-1.94033,0.100394,0.007195,0.765926 kka2_1:8_D33M,kka2_1:8_33,Kka2,kka2_1:8,P00552,,YES,33,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.186,-4.904,2.718,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.100394,0.00633568,0.756873 kka2_1:8_D33M,kka2_1:8_33,Kka2,kka2_1:8,P00552,,YES,33,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.186,-4.904,2.718,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.100394,0.00633568,0.756873 kka2_1:8_D33P,kka2_1:8_33,Kka2,kka2_1:8,P00552,,YES,33,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.186,-2.939,0.753,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.100394,0.00633568,0.714122 kka2_1:8_D33P,kka2_1:8_33,Kka2,kka2_1:8,P00552,,YES,33,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.186,-2.939,0.753,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.100394,0.00633568,0.714122 kka2_1:8_D33V,kka2_1:8_33,Kka2,kka2_1:8,P00552,,YES,33,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.186,-3.782,1.596,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.100394,0.00633568,0.758694 kka2_1:8_D33V,kka2_1:8_33,Kka2,kka2_1:8,P00552,,YES,33,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-2.186,-3.782,1.596,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.100394,0.00633568,0.758694 kka2_1:8_D33W,kka2_1:8_33,Kka2,kka2_1:8,P00552,,YES,33,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.186,-5.589,3.403,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.100394,0.00633568,0.722777 kka2_1:8_D33W,kka2_1:8_33,Kka2,kka2_1:8,P00552,,YES,33,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.186,-5.589,3.403,,0.561,S,A,0.29,3.35,2.568,,71.59,PAH,-1.306,0.100394,0.00633568,0.722777 kka2_1:8_D52M,kka2_1:8_52,Kka2,kka2_1:8,P00552,,YES,52,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.271,-4.777,2.506,,0.22,E,B,0.75,0.8,5.447,,71.59,PAH,-2.38367,0.100394,0.00175694,0.764064 kka2_1:8_D52M,kka2_1:8_52,Kka2,kka2_1:8,P00552,,YES,52,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.271,-4.777,2.506,,0.22,E,B,0.75,0.8,5.447,,71.59,PAH,-2.38367,0.100394,0.00175694,0.764064 kka2_1:8_D52P,kka2_1:8_52,Kka2,kka2_1:8,P00552,,YES,52,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.271,-3.706,1.435,,0.22,E,B,0.75,0.8,5.447,,71.59,PAH,-2.38367,0.100394,0.00175694,0.641679 kka2_1:8_D52P,kka2_1:8_52,Kka2,kka2_1:8,P00552,,YES,52,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-2.271,-3.706,1.435,,0.22,E,B,0.75,0.8,5.447,,71.59,PAH,-2.38367,0.100394,0.00175694,0.641679 kka2_1:8_D52Q,kka2_1:8_52,Kka2,kka2_1:8,P00552,,YES,52,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.271,-3.313,1.042,,0.22,E,B,0.75,0.8,5.447,,71.59,PAH,-2.38367,0.100394,0.00175694,0.797015 kka2_1:8_D52Q,kka2_1:8_52,Kka2,kka2_1:8,P00552,,YES,52,D,Q,DQ,negativeCharge,Polar,5.0516,6.24429,1.19269,61,133,146,13,111.1,143.8,32.7,-2.271,-3.313,1.042,,0.22,E,B,0.75,0.8,5.447,,71.59,PAH,-2.38367,0.100394,0.00175694,0.797015 kka2_1:8_D5C,kka2_1:8_5,Kka2,kka2_1:8,P00552,,YES,5,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.306,-4.968,3.662,,,,,,,1.147,,71.59,PAO,-1.784,0.100394,0.00222864,0.966055 kka2_1:8_D5C,kka2_1:8_5,Kka2,kka2_1:8,P00552,,YES,5,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.306,-4.968,3.662,,,,,,,1.147,,71.59,PAO,-1.784,0.100394,0.00222864,0.966055 kka2_1:8_D5I,kka2_1:8_5,Kka2,kka2_1:8,P00552,,YES,5,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.306,-3.821,2.515,,,,,,,1.147,,71.59,PAO,-1.784,0.100394,0.00222864,0.942854 kka2_1:8_D5I,kka2_1:8_5,Kka2,kka2_1:8,P00552,,YES,5,D,I,DI,negativeCharge,Hydrophobic,5.0516,6.02,0.9684,168,133,131,-2,111.1,166.7,55.6,-1.306,-3.821,2.515,,,,,,,1.147,,71.59,PAO,-1.784,0.100394,0.00222864,0.942854 kka2_1:8_D5P,kka2_1:8_5,Kka2,kka2_1:8,P00552,,YES,5,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.306,-3.466,2.16,,,,,,,1.147,,71.59,PAO,-1.784,0.100394,0.00222864,0.996041 kka2_1:8_D5P,kka2_1:8_5,Kka2,kka2_1:8,P00552,,YES,5,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.306,-3.466,2.16,,,,,,,1.147,,71.59,PAO,-1.784,0.100394,0.00222864,0.996041 kka2_1:8_D5W,kka2_1:8_5,Kka2,kka2_1:8,P00552,,YES,5,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.306,-5.278,3.972,,,,,,,1.147,,71.59,PAO,-1.784,0.100394,0.00222864,0.938368 kka2_1:8_D5W,kka2_1:8_5,Kka2,kka2_1:8,P00552,,YES,5,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.306,-5.278,3.972,,,,,,,1.147,,71.59,PAO,-1.784,0.100394,0.00222864,0.938368 kka2_1:8_D62C,kka2_1:8_62,Kka2,kka2_1:8,P00552,,YES,62,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.591,-5.15,3.559,,0.262,H,A,0.29,0.08,5.58,,64.39,PAA,-1.77833,0.100394,0.00744243,0.513724 kka2_1:8_D62C,kka2_1:8_62,Kka2,kka2_1:8,P00552,,YES,62,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.591,-5.15,3.559,,0.262,H,A,0.29,0.08,5.58,,64.39,PAA,-1.77833,0.100394,0.00744243,0.513724 kka2_1:8_D62P,kka2_1:8_62,Kka2,kka2_1:8,P00552,,YES,62,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.591,-3.966,2.375,,0.262,H,A,0.29,0.08,5.58,,64.39,PAA,-1.77833,0.100394,0.00744243,0.473247 kka2_1:8_D62P,kka2_1:8_62,Kka2,kka2_1:8,P00552,,YES,62,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.591,-3.966,2.375,,0.262,H,A,0.29,0.08,5.58,,64.39,PAA,-1.77833,0.100394,0.00744243,0.473247 kka2_1:8_D62R,kka2_1:8_62,Kka2,kka2_1:8,P00552,,YES,62,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.591,-3.972,2.381,,0.262,H,A,0.29,0.08,5.58,,64.39,PAA,-1.77833,0.100394,0.00744243,0.495325 kka2_1:8_D62R,kka2_1:8_62,Kka2,kka2_1:8,P00552,,YES,62,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.591,-3.972,2.381,,0.262,H,A,0.29,0.08,5.58,,64.39,PAA,-1.77833,0.100394,0.00744243,0.495325 kka2_1:8_D62S,kka2_1:8_62,Kka2,kka2_1:8,P00552,,YES,62,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.591,-3.356,1.765,,0.262,H,A,0.29,0.08,5.58,,64.39,PAA,-1.77833,0.100394,0.00744243,0.516539 kka2_1:8_D62S,kka2_1:8_62,Kka2,kka2_1:8,P00552,,YES,62,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.591,-3.356,1.765,,0.262,H,A,0.29,0.08,5.58,,64.39,PAA,-1.77833,0.100394,0.00744243,0.516539 kka2_1:8_D62T,kka2_1:8_62,Kka2,kka2_1:8,P00552,,YES,62,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.591,-3.648,2.057,,0.262,H,A,0.29,0.08,5.58,,64.39,PAA,-1.77833,0.100394,0.00744243,0.50473 kka2_1:8_D62T,kka2_1:8_62,Kka2,kka2_1:8,P00552,,YES,62,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.591,-3.648,2.057,,0.262,H,A,0.29,0.08,5.58,,64.39,PAA,-1.77833,0.100394,0.00744243,0.50473 kka2_1:8_D62V,kka2_1:8_62,Kka2,kka2_1:8,P00552,,YES,62,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.591,-3.746,2.155,,0.262,H,A,0.29,0.08,5.58,,64.39,PAA,-1.77833,0.100394,0.00744243,0.487439 kka2_1:8_D62V,kka2_1:8_62,Kka2,kka2_1:8,P00552,,YES,62,D,V,DV,negativeCharge,Hydrophobic,5.0516,5.60847,0.556865,152,133,117,-16,111.1,140,28.9,-1.591,-3.746,2.155,,0.262,H,A,0.29,0.08,5.58,,64.39,PAA,-1.77833,0.100394,0.00744243,0.487439 kka2_1:8_D62W,kka2_1:8_62,Kka2,kka2_1:8,P00552,,YES,62,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.591,-5.508,3.917,,0.262,H,A,0.29,0.08,5.58,,64.39,PAA,-1.77833,0.100394,0.00744243,0.433377 kka2_1:8_D62W,kka2_1:8_62,Kka2,kka2_1:8,P00552,,YES,62,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.591,-5.508,3.917,,0.262,H,A,0.29,0.08,5.58,,64.39,PAA,-1.77833,0.100394,0.00744243,0.433377 kka2_1:8_D82C,kka2_1:8_82,Kka2,kka2_1:8,P00552,,YES,82,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.946,-3.559,1.613,,0.341,E,b,0.29,0.52,7.463,,63.64,HAH,-1.98,0.100394,0.00637516,0.550579 kka2_1:8_D82C,kka2_1:8_82,Kka2,kka2_1:8,P00552,,YES,82,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.946,-3.559,1.613,,0.341,E,b,0.29,0.52,7.463,,63.64,HAH,-1.98,0.100394,0.00637516,0.550579 kka2_1:8_D82F,kka2_1:8_82,Kka2,kka2_1:8,P00552,,YES,82,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.946,-4.41,2.464,,0.341,E,b,0.29,0.52,7.463,,63.64,HAH,-1.98,0.100394,0.00637516,0.524345 kka2_1:8_D82F,kka2_1:8_82,Kka2,kka2_1:8,P00552,,YES,82,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.946,-4.41,2.464,,0.341,E,b,0.29,0.52,7.463,,63.64,HAH,-1.98,0.100394,0.00637516,0.524345 kka2_1:8_D82M,kka2_1:8_82,Kka2,kka2_1:8,P00552,,YES,82,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.946,-4.849,2.903,,0.341,E,b,0.29,0.52,7.463,,63.64,HAH,-1.98,0.100394,0.00637516,0.558133 kka2_1:8_D82M,kka2_1:8_82,Kka2,kka2_1:8,P00552,,YES,82,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.946,-4.849,2.903,,0.341,E,b,0.29,0.52,7.463,,63.64,HAH,-1.98,0.100394,0.00637516,0.558133 kka2_1:8_D82P,kka2_1:8_82,Kka2,kka2_1:8,P00552,,YES,82,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.946,-4.009,2.063,,0.341,E,b,0.29,0.52,7.463,,63.64,HAH,-1.98,0.100394,0.00637516,0.454646 kka2_1:8_D82P,kka2_1:8_82,Kka2,kka2_1:8,P00552,,YES,82,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.946,-4.009,2.063,,0.341,E,b,0.29,0.52,7.463,,63.64,HAH,-1.98,0.100394,0.00637516,0.454646 kka2_1:8_D82S,kka2_1:8_82,Kka2,kka2_1:8,P00552,,YES,82,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.946,-2.906,0.96,,0.341,E,b,0.29,0.52,7.463,,63.64,HAH,-1.98,0.100394,0.00637516,0.588913 kka2_1:8_D82S,kka2_1:8_82,Kka2,kka2_1:8,P00552,,YES,82,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-1.946,-2.906,0.96,,0.341,E,b,0.29,0.52,7.463,,63.64,HAH,-1.98,0.100394,0.00637516,0.588913 kka2_1:8_D82W,kka2_1:8_82,Kka2,kka2_1:8,P00552,,YES,82,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.946,-3.611,1.665,,0.341,E,b,0.29,0.52,7.463,,63.64,HAH,-1.98,0.100394,0.00637516,0.528775 kka2_1:8_D82W,kka2_1:8_82,Kka2,kka2_1:8,P00552,,YES,82,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.946,-3.611,1.665,,0.341,E,b,0.29,0.52,7.463,,63.64,HAH,-1.98,0.100394,0.00637516,0.528775 kka2_1:8_D90C,kka2_1:8_90,Kka2,kka2_1:8,P00552,,YES,90,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.459,-5.259,2.8,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.100394,0.00583842,0.685692 kka2_1:8_D90C,kka2_1:8_90,Kka2,kka2_1:8,P00552,,YES,90,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-2.459,-5.259,2.8,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.100394,0.00583842,0.685692 kka2_1:8_D90L,kka2_1:8_90,Kka2,kka2_1:8,P00552,,YES,90,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.459,-3.657,1.198,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.100394,0.00583842,0.538798 kka2_1:8_D90L,kka2_1:8_90,Kka2,kka2_1:8,P00552,,YES,90,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-2.459,-3.657,1.198,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.100394,0.00583842,0.538798 kka2_1:8_D90M,kka2_1:8_90,Kka2,kka2_1:8,P00552,,YES,90,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.459,-4.83,2.371,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.100394,0.00583842,0.587806 kka2_1:8_D90M,kka2_1:8_90,Kka2,kka2_1:8,P00552,,YES,90,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.459,-4.83,2.371,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.100394,0.00583842,0.587806 kka2_1:8_D90R,kka2_1:8_90,Kka2,kka2_1:8,P00552,,YES,90,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.459,-2.746,0.287,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.100394,0.00583842,0.638212 kka2_1:8_D90R,kka2_1:8_90,Kka2,kka2_1:8,P00552,,YES,90,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-2.459,-2.746,0.287,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.100394,0.00583842,0.638212 kka2_1:8_D90S,kka2_1:8_90,Kka2,kka2_1:8,P00552,,YES,90,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.459,-2.612,0.153,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.100394,0.00583842,0.654615 kka2_1:8_D90S,kka2_1:8_90,Kka2,kka2_1:8,P00552,,YES,90,D,S,DS,negativeCharge,Polar,5.0516,5.68,0.6284,65,133,105,-28,111.1,89,-22.1,-2.459,-2.612,0.153,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.100394,0.00583842,0.654615 kka2_1:8_D90T,kka2_1:8_90,Kka2,kka2_1:8,P00552,,YES,90,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.459,-3.035,0.576,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.100394,0.00583842,0.593132 kka2_1:8_D90T,kka2_1:8_90,Kka2,kka2_1:8,P00552,,YES,90,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-2.459,-3.035,0.576,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.100394,0.00583842,0.593132 kka2_1:8_D90W,kka2_1:8_90,Kka2,kka2_1:8,P00552,,YES,90,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.459,-3.595,1.136,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.100394,0.00583842,0.53334 kka2_1:8_D90W,kka2_1:8_90,Kka2,kka2_1:8,P00552,,YES,90,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.459,-3.595,1.136,,0.104,E,B,0.75,0.73,19.419,19.419,64.39,BAH,-1.72833,0.100394,0.00583842,0.53334 kka2_1:8_E111C,kka2_1:8_111,Kka2,kka2_1:8,P00552,,YES,111,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.28,-5.229,2.949,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.100394,0.00746789,0.663995 kka2_1:8_E111C,kka2_1:8_111,Kka2,kka2_1:8,P00552,,YES,111,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.28,-5.229,2.949,,0.155,H,A,1.04,-1.14,1.904,,65.53,HAB,-2.27833,0.100394,0.00746789,0.663995 kka2_1:8_E142I,kka2_1:8_142,Kka2,kka2_1:8,P00552,,YES,142,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.221,-4.073,1.852,,0.471,H,A,1.04,0.85,2.655,,65.53,HAB,-2.08033,0.100394,0.00748883,0.689599 kka2_1:8_E142I,kka2_1:8_142,Kka2,kka2_1:8,P00552,,YES,142,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.221,-4.073,1.852,,0.471,H,A,1.04,0.85,2.655,,65.53,HAB,-2.08033,0.100394,0.00748883,0.689599 kka2_1:8_E142S,kka2_1:8_142,Kka2,kka2_1:8,P00552,,YES,142,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.221,-2.618,0.397,,0.471,H,A,1.04,0.85,2.655,,65.53,HAB,-2.08033,0.100394,0.00748883,0.755058 kka2_1:8_E142S,kka2_1:8_142,Kka2,kka2_1:8,P00552,,YES,142,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.221,-2.618,0.397,,0.471,H,A,1.04,0.85,2.655,,65.53,HAB,-2.08033,0.100394,0.00748883,0.755058 kka2_1:8_E149C,kka2_1:8_149,Kka2,kka2_1:8,P00552,,YES,149,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.994,-5.217,3.223,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.100394,0.00803343,0.903386 kka2_1:8_E149C,kka2_1:8_149,Kka2,kka2_1:8,P00552,,YES,149,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.994,-5.217,3.223,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.100394,0.00803343,0.903386 kka2_1:8_E149F,kka2_1:8_149,Kka2,kka2_1:8,P00552,,YES,149,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.994,-4.387,2.393,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.100394,0.00803343,0.949541 kka2_1:8_E149F,kka2_1:8_149,Kka2,kka2_1:8,P00552,,YES,149,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.994,-4.387,2.393,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.100394,0.00803343,0.949541 kka2_1:8_E149L,kka2_1:8_149,Kka2,kka2_1:8,P00552,,YES,149,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.994,-2.522,0.528,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.100394,0.00803343,0.844601 kka2_1:8_E149L,kka2_1:8_149,Kka2,kka2_1:8,P00552,,YES,149,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.994,-2.522,0.528,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.100394,0.00803343,0.844601 kka2_1:8_E149M,kka2_1:8_149,Kka2,kka2_1:8,P00552,,YES,149,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.994,-3.564,1.57,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.100394,0.00803343,0.85982 kka2_1:8_E149M,kka2_1:8_149,Kka2,kka2_1:8,P00552,,YES,149,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.994,-3.564,1.57,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.100394,0.00803343,0.85982 kka2_1:8_E149P,kka2_1:8_149,Kka2,kka2_1:8,P00552,,YES,149,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.994,-4.051,2.057,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.100394,0.00803343,0.802987 kka2_1:8_E149P,kka2_1:8_149,Kka2,kka2_1:8,P00552,,YES,149,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.994,-4.051,2.057,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.100394,0.00803343,0.802987 kka2_1:8_E149S,kka2_1:8_149,Kka2,kka2_1:8,P00552,,YES,149,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.994,-2.804,0.81,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.100394,0.00803343,0.8554 kka2_1:8_E149S,kka2_1:8_149,Kka2,kka2_1:8,P00552,,YES,149,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.994,-2.804,0.81,,0.674,H,A,1.04,1.63,4.156,,71.59,HAH,-1.59667,0.100394,0.00803343,0.8554 kka2_1:8_E160L,kka2_1:8_160,Kka2,kka2_1:8,P00552,,YES,160,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.683,-3.761,2.078,,0.989,G,A,1.04,2.28,2.164,,71.59,AAA,-1.36133,0.100394,0.00935762,0.928366 kka2_1:8_E160L,kka2_1:8_160,Kka2,kka2_1:8,P00552,,YES,160,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.683,-3.761,2.078,,0.989,G,A,1.04,2.28,2.164,,71.59,AAA,-1.36133,0.100394,0.00935762,0.928366 kka2_1:8_E160M,kka2_1:8_160,Kka2,kka2_1:8,P00552,,YES,160,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.683,-4.919,3.236,,0.989,G,A,1.04,2.28,2.164,,71.59,AAA,-1.36133,0.100394,0.00935762,0.912631 kka2_1:8_E160M,kka2_1:8_160,Kka2,kka2_1:8,P00552,,YES,160,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.683,-4.919,3.236,,0.989,G,A,1.04,2.28,2.164,,71.59,AAA,-1.36133,0.100394,0.00935762,0.912631 kka2_1:8_E160P,kka2_1:8_160,Kka2,kka2_1:8,P00552,,YES,160,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.683,-2.472,0.789,,0.989,G,A,1.04,2.28,2.164,,71.59,AAA,-1.36133,0.100394,0.00935762,0.779572 kka2_1:8_E160P,kka2_1:8_160,Kka2,kka2_1:8,P00552,,YES,160,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.683,-2.472,0.789,,0.989,G,A,1.04,2.28,2.164,,71.59,AAA,-1.36133,0.100394,0.00935762,0.779572 kka2_1:8_E160S,kka2_1:8_160,Kka2,kka2_1:8,P00552,,YES,160,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.683,-3.324,1.641,,0.989,G,A,1.04,2.28,2.164,,71.59,AAA,-1.36133,0.100394,0.00935762,0.81545 kka2_1:8_E160S,kka2_1:8_160,Kka2,kka2_1:8,P00552,,YES,160,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.683,-3.324,1.641,,0.989,G,A,1.04,2.28,2.164,,71.59,AAA,-1.36133,0.100394,0.00935762,0.81545 kka2_1:8_E161S,kka2_1:8_161,Kka2,kka2_1:8,P00552,,YES,161,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.581,-2.422,0.841,,0.829,G,A,1.04,2.24,11.923,11.923,92.05,AAB,-1.861,0.100394,0.00760103,0.81681 kka2_1:8_E161S,kka2_1:8_161,Kka2,kka2_1:8,P00552,,YES,161,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.581,-2.422,0.841,,0.829,G,A,1.04,2.24,11.923,11.923,92.05,AAB,-1.861,0.100394,0.00760103,0.81681 kka2_1:8_E169G,kka2_1:8_169,Kka2,kka2_1:8,P00552,,YES,169,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.996,-2.941,0.945,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.100394,0.00730086,0.617941 kka2_1:8_E169G,kka2_1:8_169,Kka2,kka2_1:8,P00552,,YES,169,E,G,EG,negativeCharge,Special,3.22,3.29388,0.0738777,98,147,75,-72,138.4,60.1,-78.3,-1.996,-2.941,0.945,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.100394,0.00730086,0.617941 kka2_1:8_E169I,kka2_1:8_169,Kka2,kka2_1:8,P00552,,YES,169,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.996,-4.06,2.064,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.100394,0.00730086,0.660481 kka2_1:8_E169I,kka2_1:8_169,Kka2,kka2_1:8,P00552,,YES,169,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.996,-4.06,2.064,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.100394,0.00730086,0.660481 kka2_1:8_E169R,kka2_1:8_169,Kka2,kka2_1:8,P00552,,YES,169,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.996,-3.888,1.892,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.100394,0.00730086,0.66694 kka2_1:8_E169R,kka2_1:8_169,Kka2,kka2_1:8,P00552,,YES,169,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.996,-3.888,1.892,,0.422,H,A,1.04,0.3,1.695,,65.53,HAH,-1.755,0.100394,0.00730086,0.66694 kka2_1:8_E17I,kka2_1:8_17,Kka2,kka2_1:8,P00552,,YES,17,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.154,-4.159,2.005,,0.957,T,A,1.04,0.22,31.483,31.483,63.64,HAB,-2.432,0.100394,0.00688738,0.686533 kka2_1:8_E17I,kka2_1:8_17,Kka2,kka2_1:8,P00552,,YES,17,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-2.154,-4.159,2.005,,0.957,T,A,1.04,0.22,31.483,31.483,63.64,HAB,-2.432,0.100394,0.00688738,0.686533 kka2_1:8_E17N,kka2_1:8_17,Kka2,kka2_1:8,P00552,,YES,17,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.154,-3.14,0.986,,0.957,T,A,1.04,0.22,31.483,31.483,63.64,HAB,-2.432,0.100394,0.00688738,0.825445 kka2_1:8_E17N,kka2_1:8_17,Kka2,kka2_1:8,P00552,,YES,17,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-2.154,-3.14,0.986,,0.957,T,A,1.04,0.22,31.483,31.483,63.64,HAB,-2.432,0.100394,0.00688738,0.825445 kka2_1:8_E17T,kka2_1:8_17,Kka2,kka2_1:8,P00552,,YES,17,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.154,-2.882,0.728,,0.957,T,A,1.04,0.22,31.483,31.483,63.64,HAB,-2.432,0.100394,0.00688738,0.855278 kka2_1:8_E17T,kka2_1:8_17,Kka2,kka2_1:8,P00552,,YES,17,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.154,-2.882,0.728,,0.957,T,A,1.04,0.22,31.483,31.483,63.64,HAB,-2.432,0.100394,0.00688738,0.855278 kka2_1:8_E17V,kka2_1:8_17,Kka2,kka2_1:8,P00552,,YES,17,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.154,-3.778,1.624,,0.957,T,A,1.04,0.22,31.483,31.483,63.64,HAB,-2.432,0.100394,0.00688738,0.735643 kka2_1:8_E17V,kka2_1:8_17,Kka2,kka2_1:8,P00552,,YES,17,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-2.154,-3.778,1.624,,0.957,T,A,1.04,0.22,31.483,31.483,63.64,HAB,-2.432,0.100394,0.00688738,0.735643 kka2_1:8_E17W,kka2_1:8_17,Kka2,kka2_1:8,P00552,,YES,17,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.154,-5.592,3.438,,0.957,T,A,1.04,0.22,31.483,31.483,63.64,HAB,-2.432,0.100394,0.00688738,0.680278 kka2_1:8_E17W,kka2_1:8_17,Kka2,kka2_1:8,P00552,,YES,17,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.154,-5.592,3.438,,0.957,T,A,1.04,0.22,31.483,31.483,63.64,HAB,-2.432,0.100394,0.00688738,0.680278 kka2_1:8_E17Y,kka2_1:8_17,Kka2,kka2_1:8,P00552,,YES,17,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.154,-4.407,2.253,,0.957,T,A,1.04,0.22,31.483,31.483,63.64,HAB,-2.432,0.100394,0.00688738,0.708752 kka2_1:8_E17Y,kka2_1:8_17,Kka2,kka2_1:8,P00552,,YES,17,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-2.154,-4.407,2.253,,0.957,T,A,1.04,0.22,31.483,31.483,63.64,HAB,-2.432,0.100394,0.00688738,0.708752 kka2_1:8_E182C,kka2_1:8_182,Kka2,kka2_1:8,P00552,,YES,182,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.516,-3.433,1.917,,0.326,,B,1.52,0.75,2.568,,65.53,OAA,-1.806,0.100394,0.00641548,0.531524 kka2_1:8_E182C,kka2_1:8_182,Kka2,kka2_1:8,P00552,,YES,182,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.516,-3.433,1.917,,0.326,,B,1.52,0.75,2.568,,65.53,OAA,-1.806,0.100394,0.00641548,0.531524 kka2_1:8_E182M,kka2_1:8_182,Kka2,kka2_1:8,P00552,,YES,182,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.516,-4.818,3.302,,0.326,,B,1.52,0.75,2.568,,65.53,OAA,-1.806,0.100394,0.00641548,0.505322 kka2_1:8_E182M,kka2_1:8_182,Kka2,kka2_1:8,P00552,,YES,182,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.516,-4.818,3.302,,0.326,,B,1.52,0.75,2.568,,65.53,OAA,-1.806,0.100394,0.00641548,0.505322 kka2_1:8_E182P,kka2_1:8_182,Kka2,kka2_1:8,P00552,,YES,182,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.516,-3.948,2.432,,0.326,,B,1.52,0.75,2.568,,65.53,OAA,-1.806,0.100394,0.00641548,0.485913 kka2_1:8_E182P,kka2_1:8_182,Kka2,kka2_1:8,P00552,,YES,182,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.516,-3.948,2.432,,0.326,,B,1.52,0.75,2.568,,65.53,OAA,-1.806,0.100394,0.00641548,0.485913 kka2_1:8_E182W,kka2_1:8_182,Kka2,kka2_1:8,P00552,,YES,182,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.516,-5.341,3.825,,0.326,,B,1.52,0.75,2.568,,65.53,OAA,-1.806,0.100394,0.00641548,0.49272 kka2_1:8_E182W,kka2_1:8_182,Kka2,kka2_1:8,P00552,,YES,182,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.516,-5.341,3.825,,0.326,,B,1.52,0.75,2.568,,65.53,OAA,-1.806,0.100394,0.00641548,0.49272 kka2_1:8_E235F,kka2_1:8_235,Kka2,kka2_1:8,P00552,,YES,235,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.955,-4.481,2.526,,0.631,H,A,1.52,0.12,,,65.53,OAH,-2.07267,0.100394,0.0102806,0.824277 kka2_1:8_E235F,kka2_1:8_235,Kka2,kka2_1:8,P00552,,YES,235,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.955,-4.481,2.526,,0.631,H,A,1.52,0.12,,,65.53,OAH,-2.07267,0.100394,0.0102806,0.824277 kka2_1:8_E235M,kka2_1:8_235,Kka2,kka2_1:8,P00552,,YES,235,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.955,-4.796,2.841,,0.631,H,A,1.52,0.12,,,65.53,OAH,-2.07267,0.100394,0.0102806,0.804317 kka2_1:8_E235M,kka2_1:8_235,Kka2,kka2_1:8,P00552,,YES,235,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.955,-4.796,2.841,,0.631,H,A,1.52,0.12,,,65.53,OAH,-2.07267,0.100394,0.0102806,0.804317 kka2_1:8_E235S,kka2_1:8_235,Kka2,kka2_1:8,P00552,,YES,235,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.955,-2.915,0.96,,0.631,H,A,1.52,0.12,,,65.53,OAH,-2.07267,0.100394,0.0102806,0.680195 kka2_1:8_E235S,kka2_1:8_235,Kka2,kka2_1:8,P00552,,YES,235,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.955,-2.915,0.96,,0.631,H,A,1.52,0.12,,,65.53,OAH,-2.07267,0.100394,0.0102806,0.680195 kka2_1:8_E262R,kka2_1:8_262,Kka2,kka2_1:8,P00552,,YES,262,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-0.829,-3.509,2.68,,0.059,G,A,1.52,-0.18,0.837,,42.42,AAH,-0.816,0.100394,0.0191586,0.458615 kka2_1:8_E262R,kka2_1:8_262,Kka2,kka2_1:8,P00552,,YES,262,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-0.829,-3.509,2.68,,0.059,G,A,1.52,-0.18,0.837,,42.42,AAH,-0.816,0.100394,0.0191586,0.458615 kka2_1:8_E262S,kka2_1:8_262,Kka2,kka2_1:8,P00552,,YES,262,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-0.829,-3.212,2.383,,0.059,G,A,1.52,-0.18,0.837,,42.42,AAH,-0.816,0.100394,0.0191586,0.519701 kka2_1:8_E262S,kka2_1:8_262,Kka2,kka2_1:8,P00552,,YES,262,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-0.829,-3.212,2.383,,0.059,G,A,1.52,-0.18,0.837,,42.42,AAH,-0.816,0.100394,0.0191586,0.519701 kka2_1:8_E3M,kka2_1:8_3,Kka2,kka2_1:8,P00552,,YES,3,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.199,-4.633,2.434,,,,,,,7.22,,92.05,HAP,-2.11567,0.100394,0.00267607,1.01845 kka2_1:8_E3M,kka2_1:8_3,Kka2,kka2_1:8,P00552,,YES,3,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.199,-4.633,2.434,,,,,,,7.22,,92.05,HAP,-2.11567,0.100394,0.00267607,1.01845 kka2_1:8_E3S,kka2_1:8_3,Kka2,kka2_1:8,P00552,,YES,3,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.199,-2.253,0.054,,,,,,,7.22,,92.05,HAP,-2.11567,0.100394,0.00267607,1.00394 kka2_1:8_E3S,kka2_1:8_3,Kka2,kka2_1:8,P00552,,YES,3,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.199,-2.253,0.054,,,,,,,7.22,,92.05,HAP,-2.11567,0.100394,0.00267607,1.00394 kka2_1:8_E3T,kka2_1:8_3,Kka2,kka2_1:8,P00552,,YES,3,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.199,-3.32,1.121,,,,,,,7.22,,92.05,HAP,-2.11567,0.100394,0.00267607,1.00216 kka2_1:8_E3T,kka2_1:8_3,Kka2,kka2_1:8,P00552,,YES,3,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-2.199,-3.32,1.121,,,,,,,7.22,,92.05,HAP,-2.11567,0.100394,0.00267607,1.00216 kka2_1:8_E59A,kka2_1:8_59,Kka2,kka2_1:8,P00552,,YES,59,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-0.952,-3.166,2.214,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.100394,0.00280355,0.504423 kka2_1:8_E59A,kka2_1:8_59,Kka2,kka2_1:8,P00552,,YES,59,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-0.952,-3.166,2.214,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.100394,0.00280355,0.504423 kka2_1:8_E59C,kka2_1:8_59,Kka2,kka2_1:8,P00552,,YES,59,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-0.952,-5.289,4.337,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.100394,0.00280355,0.514026 kka2_1:8_E59C,kka2_1:8_59,Kka2,kka2_1:8,P00552,,YES,59,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-0.952,-5.289,4.337,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.100394,0.00280355,0.514026 kka2_1:8_E59H,kka2_1:8_59,Kka2,kka2_1:8,P00552,,YES,59,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-0.952,-4.372,3.42,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.100394,0.00280355,0.43466 kka2_1:8_E59H,kka2_1:8_59,Kka2,kka2_1:8,P00552,,YES,59,E,H,EH,negativeCharge,PositiveCharge,3.22,7.59,4.37,40,147,155,8,138.4,153.2,14.8,-0.952,-4.372,3.42,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.100394,0.00280355,0.43466 kka2_1:8_E59M,kka2_1:8_59,Kka2,kka2_1:8,P00552,,YES,59,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-0.952,-4.747,3.795,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.100394,0.00280355,0.450574 kka2_1:8_E59M,kka2_1:8_59,Kka2,kka2_1:8,P00552,,YES,59,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-0.952,-4.747,3.795,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.100394,0.00280355,0.450574 kka2_1:8_E59N,kka2_1:8_59,Kka2,kka2_1:8,P00552,,YES,59,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-0.952,-3.52,2.568,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.100394,0.00280355,0.428148 kka2_1:8_E59N,kka2_1:8_59,Kka2,kka2_1:8,P00552,,YES,59,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-0.952,-3.52,2.568,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.100394,0.00280355,0.428148 kka2_1:8_E59S,kka2_1:8_59,Kka2,kka2_1:8,P00552,,YES,59,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-0.952,-3.233,2.281,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.100394,0.00280355,0.537668 kka2_1:8_E59S,kka2_1:8_59,Kka2,kka2_1:8,P00552,,YES,59,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-0.952,-3.233,2.281,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.100394,0.00280355,0.537668 kka2_1:8_E59T,kka2_1:8_59,Kka2,kka2_1:8,P00552,,YES,59,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-0.952,-2.667,1.715,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.100394,0.00280355,0.563132 kka2_1:8_E59T,kka2_1:8_59,Kka2,kka2_1:8,P00552,,YES,59,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-0.952,-2.667,1.715,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.100394,0.00280355,0.563132 kka2_1:8_E59W,kka2_1:8_59,Kka2,kka2_1:8,P00552,,YES,59,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-0.952,-5.39,4.438,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.100394,0.00280355,0.423449 kka2_1:8_E59W,kka2_1:8_59,Kka2,kka2_1:8,P00552,,YES,59,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-0.952,-5.39,4.438,,0.187,,L,1.52,0.62,2.648,,50.38,PAH,-1.53,0.100394,0.00280355,0.423449 kka2_1:8_E63C,kka2_1:8_63,Kka2,kka2_1:8,P00552,,YES,63,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-0.762,-5.34,4.578,,0.043,H,A,1.52,-0.43,,,,AAH,-1.283,0.100394,0.00118399,0.455712 kka2_1:8_E63C,kka2_1:8_63,Kka2,kka2_1:8,P00552,,YES,63,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-0.762,-5.34,4.578,,0.043,H,A,1.52,-0.43,,,,AAH,-1.283,0.100394,0.00118399,0.455712 kka2_1:8_E63F,kka2_1:8_63,Kka2,kka2_1:8,P00552,,YES,63,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-0.762,-4.32,3.558,,0.043,H,A,1.52,-0.43,,,,AAH,-1.283,0.100394,0.00118399,0.383863 kka2_1:8_E63F,kka2_1:8_63,Kka2,kka2_1:8,P00552,,YES,63,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-0.762,-4.32,3.558,,0.043,H,A,1.52,-0.43,,,,AAH,-1.283,0.100394,0.00118399,0.383863 kka2_1:8_E63I,kka2_1:8_63,Kka2,kka2_1:8,P00552,,YES,63,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-0.762,-4.039,3.277,,0.043,H,A,1.52,-0.43,,,,AAH,-1.283,0.100394,0.00118399,0.383361 kka2_1:8_E63I,kka2_1:8_63,Kka2,kka2_1:8,P00552,,YES,63,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-0.762,-4.039,3.277,,0.043,H,A,1.52,-0.43,,,,AAH,-1.283,0.100394,0.00118399,0.383361 kka2_1:8_E63M,kka2_1:8_63,Kka2,kka2_1:8,P00552,,YES,63,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-0.762,-4.733,3.971,,0.043,H,A,1.52,-0.43,,,,AAH,-1.283,0.100394,0.00118399,0.41751 kka2_1:8_E63M,kka2_1:8_63,Kka2,kka2_1:8,P00552,,YES,63,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-0.762,-4.733,3.971,,0.043,H,A,1.52,-0.43,,,,AAH,-1.283,0.100394,0.00118399,0.41751 kka2_1:8_E63P,kka2_1:8_63,Kka2,kka2_1:8,P00552,,YES,63,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-0.762,-3.683,2.921,,0.043,H,A,1.52,-0.43,,,,AAH,-1.283,0.100394,0.00118399,0.422188 kka2_1:8_E63P,kka2_1:8_63,Kka2,kka2_1:8,P00552,,YES,63,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-0.762,-3.683,2.921,,0.043,H,A,1.52,-0.43,,,,AAH,-1.283,0.100394,0.00118399,0.422188 kka2_1:8_E63Q,kka2_1:8_63,Kka2,kka2_1:8,P00552,,YES,63,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-0.762,-3.253,2.491,,0.043,H,A,1.52,-0.43,,,,AAH,-1.283,0.100394,0.00118399,0.435454 kka2_1:8_E63Q,kka2_1:8_63,Kka2,kka2_1:8,P00552,,YES,63,E,Q,EQ,negativeCharge,Polar,3.22,6.24429,3.02429,29,147,146,-1,138.4,143.8,5.4,-0.762,-3.253,2.491,,0.043,H,A,1.52,-0.43,,,,AAH,-1.283,0.100394,0.00118399,0.435454 kka2_1:8_E63R,kka2_1:8_63,Kka2,kka2_1:8,P00552,,YES,63,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-0.762,-3.511,2.749,,0.043,H,A,1.52,-0.43,,,,AAH,-1.283,0.100394,0.00118399,0.438479 kka2_1:8_E63R,kka2_1:8_63,Kka2,kka2_1:8,P00552,,YES,63,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-0.762,-3.511,2.749,,0.043,H,A,1.52,-0.43,,,,AAH,-1.283,0.100394,0.00118399,0.438479 kka2_1:8_E63S,kka2_1:8_63,Kka2,kka2_1:8,P00552,,YES,63,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-0.762,-3.189,2.427,,0.043,H,A,1.52,-0.43,,,,AAH,-1.283,0.100394,0.00118399,0.481416 kka2_1:8_E63S,kka2_1:8_63,Kka2,kka2_1:8,P00552,,YES,63,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-0.762,-3.189,2.427,,0.043,H,A,1.52,-0.43,,,,AAH,-1.283,0.100394,0.00118399,0.481416 kka2_1:8_E63T,kka2_1:8_63,Kka2,kka2_1:8,P00552,,YES,63,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-0.762,-3.45,2.688,,0.043,H,A,1.52,-0.43,,,,AAH,-1.283,0.100394,0.00118399,0.450601 kka2_1:8_E63T,kka2_1:8_63,Kka2,kka2_1:8,P00552,,YES,63,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-0.762,-3.45,2.688,,0.043,H,A,1.52,-0.43,,,,AAH,-1.283,0.100394,0.00118399,0.450601 kka2_1:8_E63W,kka2_1:8_63,Kka2,kka2_1:8,P00552,,YES,63,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-0.762,-5.351,4.589,,0.043,H,A,1.52,-0.43,,,,AAH,-1.283,0.100394,0.00118399,0.386388 kka2_1:8_E63W,kka2_1:8_63,Kka2,kka2_1:8,P00552,,YES,63,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-0.762,-5.351,4.589,,0.043,H,A,1.52,-0.43,,,,AAH,-1.283,0.100394,0.00118399,0.386388 kka2_1:8_E86A,kka2_1:8_86,Kka2,kka2_1:8,P00552,,YES,86,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.86,-2.331,0.471,,0.369,,B,1.52,1.92,,,63.26,PAH,-1.98067,0.100394,0.00642858,0.686989 kka2_1:8_E86A,kka2_1:8_86,Kka2,kka2_1:8,P00552,,YES,86,E,A,EA,negativeCharge,Hydrophobic,3.22,6,2.78,107,147,89,-58,138.4,88.6,-49.8,-1.86,-2.331,0.471,,0.369,,B,1.52,1.92,,,63.26,PAH,-1.98067,0.100394,0.00642858,0.686989 kka2_1:8_E86C,kka2_1:8_86,Kka2,kka2_1:8,P00552,,YES,86,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.86,-5.228,3.368,,0.369,,B,1.52,1.92,,,63.26,PAH,-1.98067,0.100394,0.00642858,0.636046 kka2_1:8_E86C,kka2_1:8_86,Kka2,kka2_1:8,P00552,,YES,86,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.86,-5.228,3.368,,0.369,,B,1.52,1.92,,,63.26,PAH,-1.98067,0.100394,0.00642858,0.636046 kka2_1:8_E86I,kka2_1:8_86,Kka2,kka2_1:8,P00552,,YES,86,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.86,-4.165,2.305,,0.369,,B,1.52,1.92,,,63.26,PAH,-1.98067,0.100394,0.00642858,0.568149 kka2_1:8_E86I,kka2_1:8_86,Kka2,kka2_1:8,P00552,,YES,86,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.86,-4.165,2.305,,0.369,,B,1.52,1.92,,,63.26,PAH,-1.98067,0.100394,0.00642858,0.568149 kka2_1:8_E86L,kka2_1:8_86,Kka2,kka2_1:8,P00552,,YES,86,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.86,-3.758,1.898,,0.369,,B,1.52,1.92,,,63.26,PAH,-1.98067,0.100394,0.00642858,0.613275 kka2_1:8_E86L,kka2_1:8_86,Kka2,kka2_1:8,P00552,,YES,86,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.86,-3.758,1.898,,0.369,,B,1.52,1.92,,,63.26,PAH,-1.98067,0.100394,0.00642858,0.613275 kka2_1:8_E86M,kka2_1:8_86,Kka2,kka2_1:8,P00552,,YES,86,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.86,-4.913,3.053,,0.369,,B,1.52,1.92,,,63.26,PAH,-1.98067,0.100394,0.00642858,0.601514 kka2_1:8_E86M,kka2_1:8_86,Kka2,kka2_1:8,P00552,,YES,86,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.86,-4.913,3.053,,0.369,,B,1.52,1.92,,,63.26,PAH,-1.98067,0.100394,0.00642858,0.601514 kka2_1:8_E86N,kka2_1:8_86,Kka2,kka2_1:8,P00552,,YES,86,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.86,-3.654,1.794,,0.369,,B,1.52,1.92,,,63.26,PAH,-1.98067,0.100394,0.00642858,0.636581 kka2_1:8_E86N,kka2_1:8_86,Kka2,kka2_1:8,P00552,,YES,86,E,N,EN,negativeCharge,Polar,3.22,5.47157,2.25157,42,147,132,-15,138.4,114.1,-24.3,-1.86,-3.654,1.794,,0.369,,B,1.52,1.92,,,63.26,PAH,-1.98067,0.100394,0.00642858,0.636581 kka2_1:8_E86P,kka2_1:8_86,Kka2,kka2_1:8,P00552,,YES,86,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.86,-3.983,2.123,,0.369,,B,1.52,1.92,,,63.26,PAH,-1.98067,0.100394,0.00642858,0.569245 kka2_1:8_E86P,kka2_1:8_86,Kka2,kka2_1:8,P00552,,YES,86,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.86,-3.983,2.123,,0.369,,B,1.52,1.92,,,63.26,PAH,-1.98067,0.100394,0.00642858,0.569245 kka2_1:8_E86S,kka2_1:8_86,Kka2,kka2_1:8,P00552,,YES,86,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.86,-2.884,1.024,,0.369,,B,1.52,1.92,,,63.26,PAH,-1.98067,0.100394,0.00642858,0.678771 kka2_1:8_E86S,kka2_1:8_86,Kka2,kka2_1:8,P00552,,YES,86,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-1.86,-2.884,1.024,,0.369,,B,1.52,1.92,,,63.26,PAH,-1.98067,0.100394,0.00642858,0.678771 kka2_1:8_E86T,kka2_1:8_86,Kka2,kka2_1:8,P00552,,YES,86,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.86,-3.681,1.821,,0.369,,B,1.52,1.92,,,63.26,PAH,-1.98067,0.100394,0.00642858,0.61487 kka2_1:8_E86T,kka2_1:8_86,Kka2,kka2_1:8,P00552,,YES,86,E,T,ET,negativeCharge,Polar,3.22,5.6,2.38,65,147,119,-28,138.4,116.1,-22.3,-1.86,-3.681,1.821,,0.369,,B,1.52,1.92,,,63.26,PAH,-1.98067,0.100394,0.00642858,0.61487 kka2_1:8_E86V,kka2_1:8_86,Kka2,kka2_1:8,P00552,,YES,86,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.86,-3.786,1.926,,0.369,,B,1.52,1.92,,,63.26,PAH,-1.98067,0.100394,0.00642858,0.622417 kka2_1:8_E86V,kka2_1:8_86,Kka2,kka2_1:8,P00552,,YES,86,E,V,EV,negativeCharge,Hydrophobic,3.22,5.60847,2.38847,121,147,117,-30,138.4,140,1.6,-1.86,-3.786,1.926,,0.369,,B,1.52,1.92,,,63.26,PAH,-1.98067,0.100394,0.00642858,0.622417 kka2_1:8_E86W,kka2_1:8_86,Kka2,kka2_1:8,P00552,,YES,86,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.86,-5.389,3.529,,0.369,,B,1.52,1.92,,,63.26,PAH,-1.98067,0.100394,0.00642858,0.591533 kka2_1:8_E86W,kka2_1:8_86,Kka2,kka2_1:8,P00552,,YES,86,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.86,-5.389,3.529,,0.369,,B,1.52,1.92,,,63.26,PAH,-1.98067,0.100394,0.00642858,0.591533 kka2_1:8_E96C,kka2_1:8_96,Kka2,kka2_1:8,P00552,,YES,96,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.573,-4.752,2.179,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.100394,0.00369441,0.69018 kka2_1:8_E96C,kka2_1:8_96,Kka2,kka2_1:8,P00552,,YES,96,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.573,-4.752,2.179,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.100394,0.00369441,0.69018 kka2_1:8_E96S,kka2_1:8_96,Kka2,kka2_1:8,P00552,,YES,96,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.573,-3.194,0.621,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.100394,0.00369441,0.675695 kka2_1:8_E96S,kka2_1:8_96,Kka2,kka2_1:8,P00552,,YES,96,E,S,ES,negativeCharge,Polar,3.22,5.68,2.46,80,147,105,-42,138.4,89,-49.4,-2.573,-3.194,0.621,,0.476,,B,1.52,-0.65,3.172,,71.59,OAH,-2.143,0.100394,0.00369441,0.675695 kka2_1:8_F133A,kka2_1:8_133,Kka2,kka2_1:8,P00552,,YES,133,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-0.871,-3.354,2.483,,0.178,,B,1.62,0.43,1.816,,42.42,OHA,-0.871667,0.100394,0.00182168,0.483408 kka2_1:8_F133A,kka2_1:8_133,Kka2,kka2_1:8,P00552,,YES,133,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-0.871,-3.354,2.483,,0.178,,B,1.62,0.43,1.816,,42.42,OHA,-0.871667,0.100394,0.00182168,0.483408 kka2_1:8_F133E,kka2_1:8_133,Kka2,kka2_1:8,P00552,,YES,133,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-0.871,-3.916,3.045,,0.178,,B,1.62,0.43,1.816,,42.42,OHA,-0.871667,0.100394,0.00182168,0.415892 kka2_1:8_F133E,kka2_1:8_133,Kka2,kka2_1:8,P00552,,YES,133,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-0.871,-3.916,3.045,,0.178,,B,1.62,0.43,1.816,,42.42,OHA,-0.871667,0.100394,0.00182168,0.415892 kka2_1:8_F133G,kka2_1:8_133,Kka2,kka2_1:8,P00552,,YES,133,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-0.871,-3.635,2.764,,0.178,,B,1.62,0.43,1.816,,42.42,OHA,-0.871667,0.100394,0.00182168,0.472782 kka2_1:8_F133G,kka2_1:8_133,Kka2,kka2_1:8,P00552,,YES,133,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-0.871,-3.635,2.764,,0.178,,B,1.62,0.43,1.816,,42.42,OHA,-0.871667,0.100394,0.00182168,0.472782 kka2_1:8_F133N,kka2_1:8_133,Kka2,kka2_1:8,P00552,,YES,133,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-0.871,-4.149,3.278,,0.178,,B,1.62,0.43,1.816,,42.42,OHA,-0.871667,0.100394,0.00182168,0.419073 kka2_1:8_F133N,kka2_1:8_133,Kka2,kka2_1:8,P00552,,YES,133,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-0.871,-4.149,3.278,,0.178,,B,1.62,0.43,1.816,,42.42,OHA,-0.871667,0.100394,0.00182168,0.419073 kka2_1:8_F133P,kka2_1:8_133,Kka2,kka2_1:8,P00552,,YES,133,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-0.871,-4.356,3.485,,0.178,,B,1.62,0.43,1.816,,42.42,OHA,-0.871667,0.100394,0.00182168,0.464289 kka2_1:8_F133P,kka2_1:8_133,Kka2,kka2_1:8,P00552,,YES,133,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-0.871,-4.356,3.485,,0.178,,B,1.62,0.43,1.816,,42.42,OHA,-0.871667,0.100394,0.00182168,0.464289 kka2_1:8_F133T,kka2_1:8_133,Kka2,kka2_1:8,P00552,,YES,133,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-0.871,-3.698,2.827,,0.178,,B,1.62,0.43,1.816,,42.42,OHA,-0.871667,0.100394,0.00182168,0.459381 kka2_1:8_F133T,kka2_1:8_133,Kka2,kka2_1:8,P00552,,YES,133,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-0.871,-3.698,2.827,,0.178,,B,1.62,0.43,1.816,,42.42,OHA,-0.871667,0.100394,0.00182168,0.459381 kka2_1:8_F171A,kka2_1:8_171,Kka2,kka2_1:8,P00552,,YES,171,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.326,-3.394,2.068,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.100394,0.00821426,0.453034 kka2_1:8_F171A,kka2_1:8_171,Kka2,kka2_1:8,P00552,,YES,171,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-1.326,-3.394,2.068,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.100394,0.00821426,0.453034 kka2_1:8_F171D,kka2_1:8_171,Kka2,kka2_1:8,P00552,,YES,171,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.326,-4.095,2.769,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.100394,0.00821426,0.400865 kka2_1:8_F171D,kka2_1:8_171,Kka2,kka2_1:8,P00552,,YES,171,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.326,-4.095,2.769,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.100394,0.00821426,0.400865 kka2_1:8_F171H,kka2_1:8_171,Kka2,kka2_1:8,P00552,,YES,171,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.326,-3.195,1.869,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.100394,0.00821426,0.436013 kka2_1:8_F171H,kka2_1:8_171,Kka2,kka2_1:8,P00552,,YES,171,F,H,FH,Hydrophobic,PositiveCharge,3.32051,7.59,4.26949,100,165,155,-10,189.9,153.2,-36.7,-1.326,-3.195,1.869,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.100394,0.00821426,0.436013 kka2_1:8_F171P,kka2_1:8_171,Kka2,kka2_1:8,P00552,,YES,171,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.326,-4.354,3.028,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.100394,0.00821426,0.434848 kka2_1:8_F171P,kka2_1:8_171,Kka2,kka2_1:8,P00552,,YES,171,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.326,-4.354,3.028,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.100394,0.00821426,0.434848 kka2_1:8_F171Q,kka2_1:8_171,Kka2,kka2_1:8,P00552,,YES,171,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.326,-4.325,2.999,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.100394,0.00821426,0.428723 kka2_1:8_F171Q,kka2_1:8_171,Kka2,kka2_1:8,P00552,,YES,171,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.326,-4.325,2.999,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.100394,0.00821426,0.428723 kka2_1:8_F171R,kka2_1:8_171,Kka2,kka2_1:8,P00552,,YES,171,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.326,-4.175,2.849,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.100394,0.00821426,0.485251 kka2_1:8_F171R,kka2_1:8_171,Kka2,kka2_1:8,P00552,,YES,171,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.326,-4.175,2.849,,0.154,H,A,1.62,-0.1,2.528,,63.64,HHH,-1.45433,0.100394,0.00821426,0.485251 kka2_1:8_F206R,kka2_1:8_206,Kka2,kka2_1:8,P00552,,YES,206,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.349,-4.172,2.823,,0.006,E,B,1.62,-1.21,1.052,,63.64,OHH,-1.04,0.100394,0.00936868,0.475479 kka2_1:8_F206R,kka2_1:8_206,Kka2,kka2_1:8,P00552,,YES,206,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.349,-4.172,2.823,,0.006,E,B,1.62,-1.21,1.052,,63.64,OHH,-1.04,0.100394,0.00936868,0.475479 kka2_1:8_F20A,kka2_1:8_20,Kka2,kka2_1:8,P00552,,YES,20,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-3.354,-1.671,-1.683,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.100394,0.00701744,1.07649 kka2_1:8_F20A,kka2_1:8_20,Kka2,kka2_1:8,P00552,,YES,20,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-3.354,-1.671,-1.683,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.100394,0.00701744,1.07649 kka2_1:8_F20G,kka2_1:8_20,Kka2,kka2_1:8,P00552,,YES,20,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-3.354,-2.338,-1.016,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.100394,0.00701744,1.0564 kka2_1:8_F20G,kka2_1:8_20,Kka2,kka2_1:8,P00552,,YES,20,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-3.354,-2.338,-1.016,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.100394,0.00701744,1.0564 kka2_1:8_F20I,kka2_1:8_20,Kka2,kka2_1:8,P00552,,YES,20,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-3.354,-3.918,0.564,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.100394,0.00701744,0.895193 kka2_1:8_F20I,kka2_1:8_20,Kka2,kka2_1:8,P00552,,YES,20,F,I,FI,Hydrophobic,Hydrophobic,3.32051,6.02,2.69949,21,165,131,-34,189.9,166.7,-23.2,-3.354,-3.918,0.564,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.100394,0.00701744,0.895193 kka2_1:8_F20K,kka2_1:8_20,Kka2,kka2_1:8,P00552,,YES,20,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-3.354,-2.992,-0.362,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.100394,0.00701744,1.01282 kka2_1:8_F20K,kka2_1:8_20,Kka2,kka2_1:8,P00552,,YES,20,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-3.354,-2.992,-0.362,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.100394,0.00701744,1.01282 kka2_1:8_F20N,kka2_1:8_20,Kka2,kka2_1:8,P00552,,YES,20,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-3.354,-3.854,0.5,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.100394,0.00701744,0.936444 kka2_1:8_F20N,kka2_1:8_20,Kka2,kka2_1:8,P00552,,YES,20,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-3.354,-3.854,0.5,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.100394,0.00701744,0.936444 kka2_1:8_F20P,kka2_1:8_20,Kka2,kka2_1:8,P00552,,YES,20,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-3.354,-2.906,-0.448,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.100394,0.00701744,0.989338 kka2_1:8_F20P,kka2_1:8_20,Kka2,kka2_1:8,P00552,,YES,20,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-3.354,-2.906,-0.448,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.100394,0.00701744,0.989338 kka2_1:8_F20R,kka2_1:8_20,Kka2,kka2_1:8,P00552,,YES,20,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-3.354,-2.757,-0.597,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.100394,0.00701744,1.06839 kka2_1:8_F20R,kka2_1:8_20,Kka2,kka2_1:8,P00552,,YES,20,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-3.354,-2.757,-0.597,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.100394,0.00701744,1.06839 kka2_1:8_F20T,kka2_1:8_20,Kka2,kka2_1:8,P00552,,YES,20,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-3.354,-2.596,-0.758,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.100394,0.00701744,1.07603 kka2_1:8_F20T,kka2_1:8_20,Kka2,kka2_1:8,P00552,,YES,20,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-3.354,-2.596,-0.758,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.100394,0.00701744,1.07603 kka2_1:8_F20W,kka2_1:8_20,Kka2,kka2_1:8,P00552,,YES,20,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-3.354,-5.49,2.136,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.100394,0.00701744,0.948255 kka2_1:8_F20W,kka2_1:8_20,Kka2,kka2_1:8,P00552,,YES,20,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-3.354,-5.49,2.136,,0.935,T,B,0.58,-0.41,,,92.05,HHO,-1.992,0.100394,0.00701744,0.948255 kka2_1:8_F240A,kka2_1:8_240,Kka2,kka2_1:8,P00552,,YES,240,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-0.911,-3.329,2.418,,,H,A,1.62,-1.21,0.697,,50.38,BHH,-1.67267,0.100394,0.00552543,0.459495 kka2_1:8_F240A,kka2_1:8_240,Kka2,kka2_1:8,P00552,,YES,240,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-0.911,-3.329,2.418,,,H,A,1.62,-1.21,0.697,,50.38,BHH,-1.67267,0.100394,0.00552543,0.459495 kka2_1:8_F240D,kka2_1:8_240,Kka2,kka2_1:8,P00552,,YES,240,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-0.911,-4.011,3.1,,,H,A,1.62,-1.21,0.697,,50.38,BHH,-1.67267,0.100394,0.00552543,0.405852 kka2_1:8_F240D,kka2_1:8_240,Kka2,kka2_1:8,P00552,,YES,240,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-0.911,-4.011,3.1,,,H,A,1.62,-1.21,0.697,,50.38,BHH,-1.67267,0.100394,0.00552543,0.405852 kka2_1:8_F240K,kka2_1:8_240,Kka2,kka2_1:8,P00552,,YES,240,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-0.911,-3.934,3.023,,,H,A,1.62,-1.21,0.697,,50.38,BHH,-1.67267,0.100394,0.00552543,0.404755 kka2_1:8_F240K,kka2_1:8_240,Kka2,kka2_1:8,P00552,,YES,240,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-0.911,-3.934,3.023,,,H,A,1.62,-1.21,0.697,,50.38,BHH,-1.67267,0.100394,0.00552543,0.404755 kka2_1:8_F256R,kka2_1:8_256,Kka2,kka2_1:8,P00552,,YES,256,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.49,-3.099,1.609,,,H,A,1.62,-0.78,1.713,,53.03,HHH,-1.423,0.100394,0.0132841,0.514656 kka2_1:8_F256R,kka2_1:8_256,Kka2,kka2_1:8,P00552,,YES,256,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.49,-3.099,1.609,,,H,A,1.62,-0.78,1.713,,53.03,HHH,-1.423,0.100394,0.0132841,0.514656 kka2_1:8_F263A,kka2_1:8_263,Kka2,kka2_1:8,P00552,,YES,263,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-0.911,-3.329,2.418,,0.006,G,A,1.62,-0.12,0.928,,45.83,AHH,-0.92,0.100394,0.0172454,0.417714 kka2_1:8_F263A,kka2_1:8_263,Kka2,kka2_1:8,P00552,,YES,263,F,A,FA,Hydrophobic,Hydrophobic,3.32051,6,2.67949,113,165,89,-76,189.9,88.6,-101.3,-0.911,-3.329,2.418,,0.006,G,A,1.62,-0.12,0.928,,45.83,AHH,-0.92,0.100394,0.0172454,0.417714 kka2_1:8_F263D,kka2_1:8_263,Kka2,kka2_1:8,P00552,,YES,263,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-0.911,-4.011,3.1,,0.006,G,A,1.62,-0.12,0.928,,45.83,AHH,-0.92,0.100394,0.0172454,0.370582 kka2_1:8_F263D,kka2_1:8_263,Kka2,kka2_1:8,P00552,,YES,263,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-0.911,-4.011,3.1,,0.006,G,A,1.62,-0.12,0.928,,45.83,AHH,-0.92,0.100394,0.0172454,0.370582 kka2_1:8_F264R,kka2_1:8_264,Kka2,kka2_1:8,P00552,,YES,264,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.02,-4.192,3.172,,0.296,,?,1.62,0.02,1.553,,71.59,HHO,-0.9655,0.100394,,0.472584 kka2_1:8_F264R,kka2_1:8_264,Kka2,kka2_1:8,P00552,,YES,264,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.02,-4.192,3.172,,0.296,,?,1.62,0.02,1.553,,71.59,HHO,-0.9655,0.100394,,0.472584 kka2_1:8_F37C,kka2_1:8_37,Kka2,kka2_1:8,P00552,,YES,37,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.427,-4.988,3.561,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.100394,0.00586193,0.538971 kka2_1:8_F37C,kka2_1:8_37,Kka2,kka2_1:8,P00552,,YES,37,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.427,-4.988,3.561,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.100394,0.00586193,0.538971 kka2_1:8_F37E,kka2_1:8_37,Kka2,kka2_1:8,P00552,,YES,37,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.427,-3.871,2.444,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.100394,0.00586193,0.403793 kka2_1:8_F37E,kka2_1:8_37,Kka2,kka2_1:8,P00552,,YES,37,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.427,-3.871,2.444,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.100394,0.00586193,0.403793 kka2_1:8_F37K,kka2_1:8_37,Kka2,kka2_1:8,P00552,,YES,37,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.427,-3.907,2.48,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.100394,0.00586193,0.413283 kka2_1:8_F37K,kka2_1:8_37,Kka2,kka2_1:8,P00552,,YES,37,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.427,-3.907,2.48,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.100394,0.00586193,0.413283 kka2_1:8_F37N,kka2_1:8_37,Kka2,kka2_1:8,P00552,,YES,37,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.427,-4.089,2.662,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.100394,0.00586193,0.397089 kka2_1:8_F37N,kka2_1:8_37,Kka2,kka2_1:8,P00552,,YES,37,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.427,-4.089,2.662,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.100394,0.00586193,0.397089 kka2_1:8_F37P,kka2_1:8_37,Kka2,kka2_1:8,P00552,,YES,37,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.427,-4.289,2.862,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.100394,0.00586193,0.439441 kka2_1:8_F37P,kka2_1:8_37,Kka2,kka2_1:8,P00552,,YES,37,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.427,-4.289,2.862,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.100394,0.00586193,0.439441 kka2_1:8_F37T,kka2_1:8_37,Kka2,kka2_1:8,P00552,,YES,37,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.427,-3.702,2.275,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.100394,0.00586193,0.474474 kka2_1:8_F37T,kka2_1:8_37,Kka2,kka2_1:8,P00552,,YES,37,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.427,-3.702,2.275,,0.219,E,B,0.58,-0.25,2.245,,64.39,HHB,-1.17733,0.100394,0.00586193,0.474474 kka2_1:8_F48D,kka2_1:8_48,Kka2,kka2_1:8,P00552,,YES,48,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.453,-4.107,2.654,,0.296,E,B,1.62,-0.99,14.194,14.194,55.3,HHH,-1.444,0.100394,0.00475422,0.380535 kka2_1:8_F48D,kka2_1:8_48,Kka2,kka2_1:8,P00552,,YES,48,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.453,-4.107,2.654,,0.296,E,B,1.62,-0.99,14.194,14.194,55.3,HHH,-1.444,0.100394,0.00475422,0.380535 kka2_1:8_F48G,kka2_1:8_48,Kka2,kka2_1:8,P00552,,YES,48,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.453,-3.796,2.343,,0.296,E,B,1.62,-0.99,14.194,14.194,55.3,HHH,-1.444,0.100394,0.00475422,0.444122 kka2_1:8_F48G,kka2_1:8_48,Kka2,kka2_1:8,P00552,,YES,48,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.453,-3.796,2.343,,0.296,E,B,1.62,-0.99,14.194,14.194,55.3,HHH,-1.444,0.100394,0.00475422,0.444122 kka2_1:8_F48N,kka2_1:8_48,Kka2,kka2_1:8,P00552,,YES,48,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.453,-4.244,2.791,,0.296,E,B,1.62,-0.99,14.194,14.194,55.3,HHH,-1.444,0.100394,0.00475422,0.381713 kka2_1:8_F48N,kka2_1:8_48,Kka2,kka2_1:8,P00552,,YES,48,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.453,-4.244,2.791,,0.296,E,B,1.62,-0.99,14.194,14.194,55.3,HHH,-1.444,0.100394,0.00475422,0.381713 kka2_1:8_F48P,kka2_1:8_48,Kka2,kka2_1:8,P00552,,YES,48,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.453,-4.319,2.866,,0.296,E,B,1.62,-0.99,14.194,14.194,55.3,HHH,-1.444,0.100394,0.00475422,0.412692 kka2_1:8_F48P,kka2_1:8_48,Kka2,kka2_1:8,P00552,,YES,48,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.453,-4.319,2.866,,0.296,E,B,1.62,-0.99,14.194,14.194,55.3,HHH,-1.444,0.100394,0.00475422,0.412692 kka2_1:8_F48T,kka2_1:8_48,Kka2,kka2_1:8,P00552,,YES,48,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.453,-3.684,2.231,,0.296,E,B,1.62,-0.99,14.194,14.194,55.3,HHH,-1.444,0.100394,0.00475422,0.447935 kka2_1:8_F48T,kka2_1:8_48,Kka2,kka2_1:8,P00552,,YES,48,F,T,FT,Hydrophobic,Polar,3.32051,5.6,2.27949,103,165,119,-46,189.9,116.1,-73.8,-1.453,-3.684,2.231,,0.296,E,B,1.62,-0.99,14.194,14.194,55.3,HHH,-1.444,0.100394,0.00475422,0.447935 kka2_1:8_F48Y,kka2_1:8_48,Kka2,kka2_1:8,P00552,,YES,48,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.453,-1.946,0.493,,0.296,E,B,1.62,-0.99,14.194,14.194,55.3,HHH,-1.444,0.100394,0.00475422,0.599641 kka2_1:8_F48Y,kka2_1:8_48,Kka2,kka2_1:8,P00552,,YES,48,F,Y,FY,Hydrophobic,Hydrophobic,3.32051,5.66,2.33949,22,165,181,16,189.9,193.6,3.7,-1.453,-1.946,0.493,,0.296,E,B,1.62,-0.99,14.194,14.194,55.3,HHH,-1.444,0.100394,0.00475422,0.599641 kka2_1:8_G10Y,kka2_1:8_10,Kka2,kka2_1:8,P00552,,YES,10,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.921,-4.276,2.355,,,,,,,1.862,,71.59,HOP,-2.10733,0.100394,0.00289233,0.941309 kka2_1:8_G10Y,kka2_1:8_10,Kka2,kka2_1:8,P00552,,YES,10,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.921,-4.276,2.355,,,,,,,1.862,,71.59,HOP,-2.10733,0.100394,0.00289233,0.941309 kka2_1:8_G151H,kka2_1:8_151,Kka2,kka2_1:8,P00552,,YES,151,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.873,-4.645,3.772,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.100394,0.00339918,0.572718 kka2_1:8_G151H,kka2_1:8_151,Kka2,kka2_1:8,P00552,,YES,151,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.873,-4.645,3.772,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.100394,0.00339918,0.572718 kka2_1:8_G151P,kka2_1:8_151,Kka2,kka2_1:8,P00552,,YES,151,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.873,-3.953,3.08,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.100394,0.00339918,0.550935 kka2_1:8_G151P,kka2_1:8_151,Kka2,kka2_1:8,P00552,,YES,151,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.873,-3.953,3.08,,0.678,T,l,0.75,1.36,1.357,,49.62,HOH,-1.11433,0.100394,0.00339918,0.550935 kka2_1:8_G164M,kka2_1:8_164,Kka2,kka2_1:8,P00552,,YES,164,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.869,-4.95,4.081,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.100394,0.00442091,0.683154 kka2_1:8_G164M,kka2_1:8_164,Kka2,kka2_1:8,P00552,,YES,164,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.869,-4.95,4.081,,0.862,T,l,0.29,1.45,1.539,,64.39,POH,-1.828,0.100394,0.00442091,0.683154 kka2_1:8_G181M,kka2_1:8_181,Kka2,kka2_1:8,P00552,,YES,181,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-2.698,-4.828,2.13,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.100394,0.00728319,0.931527 kka2_1:8_G181M,kka2_1:8_181,Kka2,kka2_1:8,P00552,,YES,181,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-2.698,-4.828,2.13,,0.379,S,B,0.29,0.78,23.987,23.987,71.59,AOA,-2.21,0.100394,0.00728319,0.931527 kka2_1:8_G201T,kka2_1:8_201,Kka2,kka2_1:8,P00552,,YES,201,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.56,-3.028,1.468,,0.149,T,l,0.75,-0.57,2.152,,52.65,POB,-1.92233,0.100394,0.00820117,0.499227 kka2_1:8_G201T,kka2_1:8_201,Kka2,kka2_1:8,P00552,,YES,201,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.56,-3.028,1.468,,0.149,T,l,0.75,-0.57,2.152,,52.65,POB,-1.92233,0.100394,0.00820117,0.499227 kka2_1:8_G205P,kka2_1:8_205,Kka2,kka2_1:8,P00552,,YES,205,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.596,-3.908,3.312,,,E,b,0.75,-1.05,,,,POH,-1.09933,0.100394,0.00221855,0.457938 kka2_1:8_G205P,kka2_1:8_205,Kka2,kka2_1:8,P00552,,YES,205,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.596,-3.908,3.312,,,E,b,0.75,-1.05,,,,POH,-1.09933,0.100394,0.00221855,0.457938 kka2_1:8_G21M,kka2_1:8_21,Kka2,kka2_1:8,P00552,,YES,21,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.368,-4.924,3.556,,0.586,T,l,0.29,-0.75,4.889,,71.59,HOH,-2.10167,0.100394,0.00709648,0.770898 kka2_1:8_G21M,kka2_1:8_21,Kka2,kka2_1:8,P00552,,YES,21,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.368,-4.924,3.556,,0.586,T,l,0.29,-0.75,4.889,,71.59,HOH,-2.10167,0.100394,0.00709648,0.770898 kka2_1:8_G21P,kka2_1:8_21,Kka2,kka2_1:8,P00552,,YES,21,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.368,-3.965,2.597,,0.586,T,l,0.29,-0.75,4.889,,71.59,HOH,-2.10167,0.100394,0.00709648,0.718188 kka2_1:8_G21P,kka2_1:8_21,Kka2,kka2_1:8,P00552,,YES,21,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.368,-3.965,2.597,,0.586,T,l,0.29,-0.75,4.889,,71.59,HOH,-2.10167,0.100394,0.00709648,0.718188 kka2_1:8_G21W,kka2_1:8_21,Kka2,kka2_1:8,P00552,,YES,21,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.368,-5.423,4.055,,0.586,T,l,0.29,-0.75,4.889,,71.59,HOH,-2.10167,0.100394,0.00709648,0.72787 kka2_1:8_G21W,kka2_1:8_21,Kka2,kka2_1:8,P00552,,YES,21,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.368,-5.423,4.055,,0.586,T,l,0.29,-0.75,4.889,,71.59,HOH,-2.10167,0.100394,0.00709648,0.72787 kka2_1:8_G21Y,kka2_1:8_21,Kka2,kka2_1:8,P00552,,YES,21,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.368,-4.271,2.903,,0.586,T,l,0.29,-0.75,4.889,,71.59,HOH,-2.10167,0.100394,0.00709648,0.74267 kka2_1:8_G21Y,kka2_1:8_21,Kka2,kka2_1:8,P00552,,YES,21,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.368,-4.271,2.903,,0.586,T,l,0.29,-0.75,4.889,,71.59,HOH,-2.10167,0.100394,0.00709648,0.74267 kka2_1:8_G245I,kka2_1:8_245,Kka2,kka2_1:8,P00552,,YES,245,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.812,-4.212,3.4,,0.655,T,g,0.75,0.03,1.148,,65.53,HOH,-1.19833,0.100394,0.00683899,0.450932 kka2_1:8_G245I,kka2_1:8_245,Kka2,kka2_1:8,P00552,,YES,245,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.812,-4.212,3.4,,0.655,T,g,0.75,0.03,1.148,,65.53,HOH,-1.19833,0.100394,0.00683899,0.450932 kka2_1:8_G30K,kka2_1:8_30,Kka2,kka2_1:8,P00552,,YES,30,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.596,-3.71,3.114,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.100394,0.00159208,0.435385 kka2_1:8_G30K,kka2_1:8_30,Kka2,kka2_1:8,P00552,,YES,30,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.596,-3.71,3.114,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.100394,0.00159208,0.435385 kka2_1:8_G30M,kka2_1:8_30,Kka2,kka2_1:8,P00552,,YES,30,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.596,-4.958,4.362,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.100394,0.00159208,0.472335 kka2_1:8_G30M,kka2_1:8_30,Kka2,kka2_1:8,P00552,,YES,30,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.596,-4.958,4.362,,0.54,S,g,0.75,3.76,,,,HOO,-1.51133,0.100394,0.00159208,0.472335 kka2_1:8_G43H,kka2_1:8_43,Kka2,kka2_1:8,P00552,,YES,43,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.587,-4.654,3.067,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.100394,0.0071925,0.717737 kka2_1:8_G43H,kka2_1:8_43,Kka2,kka2_1:8,P00552,,YES,43,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.587,-4.654,3.067,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.100394,0.0071925,0.717737 kka2_1:8_G43L,kka2_1:8_43,Kka2,kka2_1:8,P00552,,YES,43,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.587,-3.778,2.191,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.100394,0.0071925,0.689541 kka2_1:8_G43L,kka2_1:8_43,Kka2,kka2_1:8,P00552,,YES,43,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.587,-3.778,2.191,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.100394,0.0071925,0.689541 kka2_1:8_G43N,kka2_1:8_43,Kka2,kka2_1:8,P00552,,YES,43,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.587,-2.611,1.024,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.100394,0.0071925,0.815884 kka2_1:8_G43N,kka2_1:8_43,Kka2,kka2_1:8,P00552,,YES,43,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.587,-2.611,1.024,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.100394,0.0071925,0.815884 kka2_1:8_G43Q,kka2_1:8_43,Kka2,kka2_1:8,P00552,,YES,43,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.587,-3.198,1.611,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.100394,0.0071925,0.762119 kka2_1:8_G43Q,kka2_1:8_43,Kka2,kka2_1:8,P00552,,YES,43,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.587,-3.198,1.611,,0.862,T,l,0.29,-0.67,2.247,,63.26,POB,-2.18533,0.100394,0.0071925,0.762119 kka2_1:8_G55I,kka2_1:8_55,Kka2,kka2_1:8,P00552,,YES,55,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.625,-3.229,1.604,,0.517,S,b,0.29,1.19,8.881,,63.64,POH,-2.05967,0.100394,0.00667877,0.601628 kka2_1:8_G55I,kka2_1:8_55,Kka2,kka2_1:8,P00552,,YES,55,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.625,-3.229,1.604,,0.517,S,b,0.29,1.19,8.881,,63.64,POH,-2.05967,0.100394,0.00667877,0.601628 kka2_1:8_G55Y,kka2_1:8_55,Kka2,kka2_1:8,P00552,,YES,55,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.625,-4.276,2.651,,0.517,S,b,0.29,1.19,8.881,,63.64,POH,-2.05967,0.100394,0.00667877,0.562243 kka2_1:8_G55Y,kka2_1:8_55,Kka2,kka2_1:8,P00552,,YES,55,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.625,-4.276,2.651,,0.517,S,b,0.29,1.19,8.881,,63.64,POH,-2.05967,0.100394,0.00667877,0.562243 kka2_1:8_G6I,kka2_1:8_6,Kka2,kka2_1:8,P00552,,YES,6,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.685,-3.841,2.156,,,,,,,,,71.59,AOH,-1.639,0.100394,0.00204693,1.04477 kka2_1:8_G6I,kka2_1:8_6,Kka2,kka2_1:8,P00552,,YES,6,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.685,-3.841,2.156,,,,,,,,,71.59,AOH,-1.639,0.100394,0.00204693,1.04477 kka2_1:8_G88F,kka2_1:8_88,Kka2,kka2_1:8,P00552,,YES,88,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.689,-4.477,2.788,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.100394,0.00685559,0.615773 kka2_1:8_G88F,kka2_1:8_88,Kka2,kka2_1:8,P00552,,YES,88,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.689,-4.477,2.788,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.100394,0.00685559,0.615773 kka2_1:8_G88H,kka2_1:8_88,Kka2,kka2_1:8,P00552,,YES,88,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.689,-3.199,1.51,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.100394,0.00685559,0.661855 kka2_1:8_G88H,kka2_1:8_88,Kka2,kka2_1:8,P00552,,YES,88,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.689,-3.199,1.51,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.100394,0.00685559,0.661855 kka2_1:8_G88K,kka2_1:8_88,Kka2,kka2_1:8,P00552,,YES,88,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.689,-3.033,1.344,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.100394,0.00685559,0.68089 kka2_1:8_G88K,kka2_1:8_88,Kka2,kka2_1:8,P00552,,YES,88,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.689,-3.033,1.344,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.100394,0.00685559,0.68089 kka2_1:8_G88M,kka2_1:8_88,Kka2,kka2_1:8,P00552,,YES,88,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.689,-4.913,3.224,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.100394,0.00685559,0.639882 kka2_1:8_G88M,kka2_1:8_88,Kka2,kka2_1:8,P00552,,YES,88,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.689,-4.913,3.224,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.100394,0.00685559,0.639882 kka2_1:8_G88P,kka2_1:8_88,Kka2,kka2_1:8,P00552,,YES,88,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.689,-4.037,2.348,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.100394,0.00685559,0.569177 kka2_1:8_G88P,kka2_1:8_88,Kka2,kka2_1:8,P00552,,YES,88,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.689,-4.037,2.348,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.100394,0.00685559,0.569177 kka2_1:8_G88Q,kka2_1:8_88,Kka2,kka2_1:8,P00552,,YES,88,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.689,-2.821,1.132,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.100394,0.00685559,0.699786 kka2_1:8_G88Q,kka2_1:8_88,Kka2,kka2_1:8,P00552,,YES,88,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.689,-2.821,1.132,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.100394,0.00685559,0.699786 kka2_1:8_G88W,kka2_1:8_88,Kka2,kka2_1:8,P00552,,YES,88,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.689,-5.544,3.855,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.100394,0.00685559,0.616334 kka2_1:8_G88W,kka2_1:8_88,Kka2,kka2_1:8,P00552,,YES,88,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.689,-5.544,3.855,,0.54,S,l,0.75,1.51,7.899,,65.53,HOB,-1.718,0.100394,0.00685559,0.616334 kka2_1:8_G99P,kka2_1:8_99,Kka2,kka2_1:8,P00552,,YES,99,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.596,-3.908,3.312,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.100394,0.00186055,0.47729 kka2_1:8_G99P,kka2_1:8_99,Kka2,kka2_1:8,P00552,,YES,99,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.596,-3.908,3.312,,0.368,S,g,0.75,-0.87,,,,OOP,-1.63067,0.100394,0.00186055,0.47729 kka2_1:8_H106C,kka2_1:8_106,Kka2,kka2_1:8,P00552,,YES,106,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-3.13,-5.214,2.084,,1.065,,a,0.87,-0.95,15.956,15.956,71.59,PBH,-2.10433,0.100394,0.00730778,0.911489 kka2_1:8_H106C,kka2_1:8_106,Kka2,kka2_1:8,P00552,,YES,106,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-3.13,-5.214,2.084,,1.065,,a,0.87,-0.95,15.956,15.956,71.59,PBH,-2.10433,0.100394,0.00730778,0.911489 kka2_1:8_H106G,kka2_1:8_106,Kka2,kka2_1:8,P00552,,YES,106,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-3.13,-2.689,-0.441,,1.065,,a,0.87,-0.95,15.956,15.956,71.59,PBH,-2.10433,0.100394,0.00730778,1.02459 kka2_1:8_H106G,kka2_1:8_106,Kka2,kka2_1:8,P00552,,YES,106,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-3.13,-2.689,-0.441,,1.065,,a,0.87,-0.95,15.956,15.956,71.59,PBH,-2.10433,0.100394,0.00730778,1.02459 kka2_1:8_H106M,kka2_1:8_106,Kka2,kka2_1:8,P00552,,YES,106,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-3.13,-4.852,1.722,,1.065,,a,0.87,-0.95,15.956,15.956,71.59,PBH,-2.10433,0.100394,0.00730778,0.725792 kka2_1:8_H106M,kka2_1:8_106,Kka2,kka2_1:8,P00552,,YES,106,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-3.13,-4.852,1.722,,1.065,,a,0.87,-0.95,15.956,15.956,71.59,PBH,-2.10433,0.100394,0.00730778,0.725792 kka2_1:8_H106S,kka2_1:8_106,Kka2,kka2_1:8,P00552,,YES,106,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-3.13,-2.484,-0.646,,1.065,,a,0.87,-0.95,15.956,15.956,71.59,PBH,-2.10433,0.100394,0.00730778,1.04874 kka2_1:8_H106S,kka2_1:8_106,Kka2,kka2_1:8,P00552,,YES,106,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-3.13,-2.484,-0.646,,1.065,,a,0.87,-0.95,15.956,15.956,71.59,PBH,-2.10433,0.100394,0.00730778,1.04874 kka2_1:8_H106T,kka2_1:8_106,Kka2,kka2_1:8,P00552,,YES,106,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-3.13,-2.51,-0.62,,1.065,,a,0.87,-0.95,15.956,15.956,71.59,PBH,-2.10433,0.100394,0.00730778,1.04841 kka2_1:8_H106T,kka2_1:8_106,Kka2,kka2_1:8,P00552,,YES,106,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-3.13,-2.51,-0.62,,1.065,,a,0.87,-0.95,15.956,15.956,71.59,PBH,-2.10433,0.100394,0.00730778,1.04841 kka2_1:8_H124A,kka2_1:8_124,Kka2,kka2_1:8,P00552,,YES,124,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-0.84,-3.331,2.491,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.100394,0.00211296,0.429197 kka2_1:8_H124A,kka2_1:8_124,Kka2,kka2_1:8,P00552,,YES,124,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-0.84,-3.331,2.491,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.100394,0.00211296,0.429197 kka2_1:8_H124C,kka2_1:8_124,Kka2,kka2_1:8,P00552,,YES,124,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-0.84,-5.115,4.275,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.100394,0.00211296,0.462053 kka2_1:8_H124C,kka2_1:8_124,Kka2,kka2_1:8,P00552,,YES,124,H,C,HC,PositiveCharge,Special,7.59,5.07,-2.52,174,155,121,-34,153.2,108.5,-44.7,-0.84,-5.115,4.275,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.100394,0.00211296,0.462053 kka2_1:8_H124E,kka2_1:8_124,Kka2,kka2_1:8,P00552,,YES,124,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-0.84,-3.243,2.403,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.100394,0.00211296,0.453287 kka2_1:8_H124E,kka2_1:8_124,Kka2,kka2_1:8,P00552,,YES,124,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-0.84,-3.243,2.403,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.100394,0.00211296,0.453287 kka2_1:8_H124F,kka2_1:8_124,Kka2,kka2_1:8,P00552,,YES,124,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-0.84,-3.87,3.03,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.100394,0.00211296,0.425668 kka2_1:8_H124F,kka2_1:8_124,Kka2,kka2_1:8,P00552,,YES,124,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-0.84,-3.87,3.03,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.100394,0.00211296,0.425668 kka2_1:8_H124L,kka2_1:8_124,Kka2,kka2_1:8,P00552,,YES,124,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-0.84,-3.611,2.771,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.100394,0.00211296,0.446499 kka2_1:8_H124L,kka2_1:8_124,Kka2,kka2_1:8,P00552,,YES,124,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-0.84,-3.611,2.771,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.100394,0.00211296,0.446499 kka2_1:8_H124M,kka2_1:8_124,Kka2,kka2_1:8,P00552,,YES,124,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-0.84,-4.733,3.893,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.100394,0.00211296,0.449099 kka2_1:8_H124M,kka2_1:8_124,Kka2,kka2_1:8,P00552,,YES,124,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-0.84,-4.733,3.893,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.100394,0.00211296,0.449099 kka2_1:8_H124S,kka2_1:8_124,Kka2,kka2_1:8,P00552,,YES,124,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-0.84,-3.414,2.574,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.100394,0.00211296,0.455974 kka2_1:8_H124S,kka2_1:8_124,Kka2,kka2_1:8,P00552,,YES,124,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-0.84,-3.414,2.574,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.100394,0.00211296,0.455974 kka2_1:8_H124V,kka2_1:8_124,Kka2,kka2_1:8,P00552,,YES,124,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-0.84,-3.782,2.942,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.100394,0.00211296,0.433872 kka2_1:8_H124V,kka2_1:8_124,Kka2,kka2_1:8,P00552,,YES,124,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-0.84,-3.782,2.942,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.100394,0.00211296,0.433872 kka2_1:8_H124W,kka2_1:8_124,Kka2,kka2_1:8,P00552,,YES,124,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-0.84,-5.126,4.286,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.100394,0.00211296,0.407555 kka2_1:8_H124W,kka2_1:8_124,Kka2,kka2_1:8,P00552,,YES,124,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-0.84,-5.126,4.286,,0.076,T,A,0.17,-0.63,,,,HBP,-1.45,0.100394,0.00211296,0.407555 kka2_1:8_H139A,kka2_1:8_139,Kka2,kka2_1:8,P00552,,YES,139,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-2.809,-2.449,-0.36,,0.471,H,A,0.17,0.68,28.583,28.583,63.64,BBB,-2.22,0.100394,0.00734779,0.879237 kka2_1:8_H139A,kka2_1:8_139,Kka2,kka2_1:8,P00552,,YES,139,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-2.809,-2.449,-0.36,,0.471,H,A,0.17,0.68,28.583,28.583,63.64,BBB,-2.22,0.100394,0.00734779,0.879237 kka2_1:8_H139E,kka2_1:8_139,Kka2,kka2_1:8,P00552,,YES,139,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-2.809,-2.979,0.17,,0.471,H,A,0.17,0.68,28.583,28.583,63.64,BBB,-2.22,0.100394,0.00734779,0.815788 kka2_1:8_H139E,kka2_1:8_139,Kka2,kka2_1:8,P00552,,YES,139,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-2.809,-2.979,0.17,,0.471,H,A,0.17,0.68,28.583,28.583,63.64,BBB,-2.22,0.100394,0.00734779,0.815788 kka2_1:8_H139M,kka2_1:8_139,Kka2,kka2_1:8,P00552,,YES,139,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-2.809,-3.708,0.899,,0.471,H,A,0.17,0.68,28.583,28.583,63.64,BBB,-2.22,0.100394,0.00734779,0.757757 kka2_1:8_H139M,kka2_1:8_139,Kka2,kka2_1:8,P00552,,YES,139,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-2.809,-3.708,0.899,,0.471,H,A,0.17,0.68,28.583,28.583,63.64,BBB,-2.22,0.100394,0.00734779,0.757757 kka2_1:8_H139V,kka2_1:8_139,Kka2,kka2_1:8,P00552,,YES,139,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-2.809,-2.837,0.028,,0.471,H,A,0.17,0.68,28.583,28.583,63.64,BBB,-2.22,0.100394,0.00734779,0.829705 kka2_1:8_H139V,kka2_1:8_139,Kka2,kka2_1:8,P00552,,YES,139,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-2.809,-2.837,0.028,,0.471,H,A,0.17,0.68,28.583,28.583,63.64,BBB,-2.22,0.100394,0.00734779,0.829705 kka2_1:8_H139W,kka2_1:8_139,Kka2,kka2_1:8,P00552,,YES,139,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-2.809,-5.517,2.708,,0.471,H,A,0.17,0.68,28.583,28.583,63.64,BBB,-2.22,0.100394,0.00734779,0.861536 kka2_1:8_H139W,kka2_1:8_139,Kka2,kka2_1:8,P00552,,YES,139,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-2.809,-5.517,2.708,,0.471,H,A,0.17,0.68,28.583,28.583,63.64,BBB,-2.22,0.100394,0.00734779,0.861536 kka2_1:8_H162A,kka2_1:8_162,Kka2,kka2_1:8,P00552,,YES,162,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-2.319,-3.316,0.997,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.100394,0.00616145,0.464783 kka2_1:8_H162A,kka2_1:8_162,Kka2,kka2_1:8,P00552,,YES,162,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-2.319,-3.316,0.997,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.100394,0.00616145,0.464783 kka2_1:8_H162G,kka2_1:8_162,Kka2,kka2_1:8,P00552,,YES,162,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-2.319,-3.406,1.087,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.100394,0.00616145,0.450186 kka2_1:8_H162G,kka2_1:8_162,Kka2,kka2_1:8,P00552,,YES,162,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-2.319,-3.406,1.087,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.100394,0.00616145,0.450186 kka2_1:8_H162S,kka2_1:8_162,Kka2,kka2_1:8,P00552,,YES,162,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-2.319,-3.471,1.152,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.100394,0.00616145,0.482895 kka2_1:8_H162S,kka2_1:8_162,Kka2,kka2_1:8,P00552,,YES,162,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-2.319,-3.471,1.152,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.100394,0.00616145,0.482895 kka2_1:8_H162T,kka2_1:8_162,Kka2,kka2_1:8,P00552,,YES,162,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-2.319,-3.571,1.252,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.100394,0.00616145,0.462242 kka2_1:8_H162T,kka2_1:8_162,Kka2,kka2_1:8,P00552,,YES,162,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-2.319,-3.571,1.252,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.100394,0.00616145,0.462242 kka2_1:8_H162W,kka2_1:8_162,Kka2,kka2_1:8,P00552,,YES,162,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-2.319,-2.828,0.509,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.100394,0.00616145,0.551968 kka2_1:8_H162W,kka2_1:8_162,Kka2,kka2_1:8,P00552,,YES,162,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-2.319,-2.828,0.509,,0.071,G,A,0.87,1.01,3.187,,64.39,ABP,-2.02067,0.100394,0.00616145,0.551968 kka2_1:8_H8M,kka2_1:8_8,Kka2,kka2_1:8,P00552,,YES,8,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-2.759,-4.438,1.679,,,,,,,,,71.59,HBH,-2.25467,0.100394,0.00256422,1.02057 kka2_1:8_H8M,kka2_1:8_8,Kka2,kka2_1:8,P00552,,YES,8,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-2.759,-4.438,1.679,,,,,,,,,71.59,HBH,-2.25467,0.100394,0.00256422,1.02057 kka2_1:8_H8P,kka2_1:8_8,Kka2,kka2_1:8,P00552,,YES,8,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-2.759,-3.809,1.05,,,,,,,,,71.59,HBH,-2.25467,0.100394,0.00256422,0.960864 kka2_1:8_H8P,kka2_1:8_8,Kka2,kka2_1:8,P00552,,YES,8,H,P,HP,PositiveCharge,Special,7.59,6.3,-1.29,77,155,115,-40,153.2,112.7,-40.5,-2.759,-3.809,1.05,,,,,,,,,71.59,HBH,-2.25467,0.100394,0.00256422,0.960864 kka2_1:8_H8S,kka2_1:8_8,Kka2,kka2_1:8,P00552,,YES,8,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-2.759,-2.388,-0.371,,,,,,,,,71.59,HBH,-2.25467,0.100394,0.00256422,1.05279 kka2_1:8_H8S,kka2_1:8_8,Kka2,kka2_1:8,P00552,,YES,8,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-2.759,-2.388,-0.371,,,,,,,,,71.59,HBH,-2.25467,0.100394,0.00256422,1.05279 kka2_1:8_I141A,kka2_1:8_141,Kka2,kka2_1:8,P00552,,YES,141,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.495,-3.207,1.712,,0.068,H,A,1.52,-0.01,2.144,,92.05,BHA,-1.689,0.100394,0.00744745,0.449491 kka2_1:8_I141A,kka2_1:8_141,Kka2,kka2_1:8,P00552,,YES,141,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.495,-3.207,1.712,,0.068,H,A,1.52,-0.01,2.144,,92.05,BHA,-1.689,0.100394,0.00744745,0.449491 kka2_1:8_I141G,kka2_1:8_141,Kka2,kka2_1:8,P00552,,YES,141,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.495,-3.916,2.421,,0.068,H,A,1.52,-0.01,2.144,,92.05,BHA,-1.689,0.100394,0.00744745,0.461982 kka2_1:8_I141G,kka2_1:8_141,Kka2,kka2_1:8,P00552,,YES,141,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.495,-3.916,2.421,,0.068,H,A,1.52,-0.01,2.144,,92.05,BHA,-1.689,0.100394,0.00744745,0.461982 kka2_1:8_I141P,kka2_1:8_141,Kka2,kka2_1:8,P00552,,YES,141,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.495,-4.213,2.718,,0.068,H,A,1.52,-0.01,2.144,,92.05,BHA,-1.689,0.100394,0.00744745,0.46046 kka2_1:8_I141P,kka2_1:8_141,Kka2,kka2_1:8,P00552,,YES,141,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.495,-4.213,2.718,,0.068,H,A,1.52,-0.01,2.144,,92.05,BHA,-1.689,0.100394,0.00744745,0.46046 kka2_1:8_I141R,kka2_1:8_141,Kka2,kka2_1:8,P00552,,YES,141,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.495,-4.204,2.709,,0.068,H,A,1.52,-0.01,2.144,,92.05,BHA,-1.689,0.100394,0.00744745,0.53678 kka2_1:8_I141R,kka2_1:8_141,Kka2,kka2_1:8,P00552,,YES,141,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.495,-4.204,2.709,,0.068,H,A,1.52,-0.01,2.144,,92.05,BHA,-1.689,0.100394,0.00744745,0.53678 kka2_1:8_I141W,kka2_1:8_141,Kka2,kka2_1:8,P00552,,YES,141,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.495,-5.368,3.873,,0.068,H,A,1.52,-0.01,2.144,,92.05,BHA,-1.689,0.100394,0.00744745,0.461515 kka2_1:8_I141W,kka2_1:8_141,Kka2,kka2_1:8,P00552,,YES,141,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.495,-5.368,3.873,,0.068,H,A,1.52,-0.01,2.144,,92.05,BHA,-1.689,0.100394,0.00744745,0.461515 kka2_1:8_I221A,kka2_1:8_221,Kka2,kka2_1:8,P00552,,YES,221,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.739,-3.216,1.477,,,H,A,1.52,-1.15,1.599,,71.59,AHH,-1.08367,0.100394,0.00945908,0.50114 kka2_1:8_I221A,kka2_1:8_221,Kka2,kka2_1:8,P00552,,YES,221,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.739,-3.216,1.477,,,H,A,1.52,-1.15,1.599,,71.59,AHH,-1.08367,0.100394,0.00945908,0.50114 kka2_1:8_I246D,kka2_1:8_246,Kka2,kka2_1:8,P00552,,YES,246,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-2.008,-3.218,1.21,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.100394,0.0139479,0.572271 kka2_1:8_I246D,kka2_1:8_246,Kka2,kka2_1:8,P00552,,YES,246,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-2.008,-3.218,1.21,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.100394,0.0139479,0.572271 kka2_1:8_I246F,kka2_1:8_246,Kka2,kka2_1:8,P00552,,YES,246,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-2.008,-3.274,1.266,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.100394,0.0139479,0.581035 kka2_1:8_I246F,kka2_1:8_246,Kka2,kka2_1:8,P00552,,YES,246,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-2.008,-3.274,1.266,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.100394,0.0139479,0.581035 kka2_1:8_I246G,kka2_1:8_246,Kka2,kka2_1:8,P00552,,YES,246,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-2.008,-2.463,0.455,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.100394,0.0139479,0.720992 kka2_1:8_I246G,kka2_1:8_246,Kka2,kka2_1:8,P00552,,YES,246,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-2.008,-2.463,0.455,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.100394,0.0139479,0.720992 kka2_1:8_I246Q,kka2_1:8_246,Kka2,kka2_1:8,P00552,,YES,246,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-2.008,-4.292,2.284,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.100394,0.0139479,0.689669 kka2_1:8_I246Q,kka2_1:8_246,Kka2,kka2_1:8,P00552,,YES,246,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-2.008,-4.292,2.284,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.100394,0.0139479,0.689669 kka2_1:8_I246W,kka2_1:8_246,Kka2,kka2_1:8,P00552,,YES,246,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-2.008,-5.452,3.444,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.100394,0.0139479,0.649654 kka2_1:8_I246W,kka2_1:8_246,Kka2,kka2_1:8,P00552,,YES,246,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-2.008,-5.452,3.444,,0.165,.,B,0.48,-0.01,25.674,25.674,65.53,OHH,-1.75967,0.100394,0.0139479,0.649654 kka2_1:8_I254R,kka2_1:8_254,Kka2,kka2_1:8,P00552,,YES,254,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.933,-3.154,1.221,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.100394,0.0132375,0.525438 kka2_1:8_I254R,kka2_1:8_254,Kka2,kka2_1:8,P00552,,YES,254,I,R,IR,Hydrophobic,PositiveCharge,6.02,6.34148,0.321478,97,131,174,43,166.7,173.4,6.7,-1.933,-3.154,1.221,,0.135,H,A,0.48,-0.6,1.849,,71.59,BHH,-1.668,0.100394,0.0132375,0.525438 kka2_1:8_I29C,kka2_1:8_29,Kka2,kka2_1:8,P00552,,YES,29,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.692,-4.988,3.296,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.100394,0.00619521,0.706131 kka2_1:8_I29C,kka2_1:8_29,Kka2,kka2_1:8,P00552,,YES,29,I,C,IC,Hydrophobic,Special,6.02,5.07,-0.95,198,131,121,-10,166.7,108.5,-58.2,-1.692,-4.988,3.296,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.100394,0.00619521,0.706131 kka2_1:8_I29E,kka2_1:8_29,Kka2,kka2_1:8,P00552,,YES,29,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.692,-2.793,1.101,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.100394,0.00619521,0.784862 kka2_1:8_I29E,kka2_1:8_29,Kka2,kka2_1:8,P00552,,YES,29,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.692,-2.793,1.101,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.100394,0.00619521,0.784862 kka2_1:8_I29G,kka2_1:8_29,Kka2,kka2_1:8,P00552,,YES,29,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.692,-2.967,1.275,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.100394,0.00619521,0.789246 kka2_1:8_I29G,kka2_1:8_29,Kka2,kka2_1:8,P00552,,YES,29,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.692,-2.967,1.275,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.100394,0.00619521,0.789246 kka2_1:8_I29P,kka2_1:8_29,Kka2,kka2_1:8,P00552,,YES,29,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.692,-4.154,2.462,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.100394,0.00619521,0.629387 kka2_1:8_I29P,kka2_1:8_29,Kka2,kka2_1:8,P00552,,YES,29,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.692,-4.154,2.462,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.100394,0.00619521,0.629387 kka2_1:8_I29W,kka2_1:8_29,Kka2,kka2_1:8,P00552,,YES,29,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.692,-5.447,3.755,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.100394,0.00619521,0.660386 kka2_1:8_I29W,kka2_1:8_29,Kka2,kka2_1:8,P00552,,YES,29,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.692,-5.447,3.755,,1.293,,a,1.52,3.22,1.392,,71.59,PHO,-1.39033,0.100394,0.00619521,0.660386 kka2_1:8_I2A,kka2_1:8_2,Kka2,kka2_1:8,P00552,,YES,2,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.787,-2.783,0.996,,,,,,,,,71.59,HHA,-1.92433,0.100394,0.00246644,0.968055 kka2_1:8_I2A,kka2_1:8_2,Kka2,kka2_1:8,P00552,,YES,2,I,A,IA,Hydrophobic,Hydrophobic,6.02,6,-0.02,94,131,89,-42,166.7,88.6,-78.1,-1.787,-2.783,0.996,,,,,,,,,71.59,HHA,-1.92433,0.100394,0.00246644,0.968055 kka2_1:8_K112A,kka2_1:8_112,Kka2,kka2_1:8,P00552,,YES,112,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-2.491,-2.624,0.133,,0.076,H,A,1.3,-1.37,10.58,10.58,56.06,ABH,-2.00133,0.100394,0.00645389,0.579385 kka2_1:8_K112A,kka2_1:8_112,Kka2,kka2_1:8,P00552,,YES,112,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-2.491,-2.624,0.133,,0.076,H,A,1.3,-1.37,10.58,10.58,56.06,ABH,-2.00133,0.100394,0.00645389,0.579385 kka2_1:8_K112G,kka2_1:8_112,Kka2,kka2_1:8,P00552,,YES,112,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-2.491,-3.699,1.208,,0.076,H,A,1.3,-1.37,10.58,10.58,56.06,ABH,-2.00133,0.100394,0.00645389,0.484571 kka2_1:8_K112G,kka2_1:8_112,Kka2,kka2_1:8,P00552,,YES,112,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-2.491,-3.699,1.208,,0.076,H,A,1.3,-1.37,10.58,10.58,56.06,ABH,-2.00133,0.100394,0.00645389,0.484571 kka2_1:8_K112V,kka2_1:8_112,Kka2,kka2_1:8,P00552,,YES,112,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-2.491,-2.276,-0.215,,0.076,H,A,1.3,-1.37,10.58,10.58,56.06,ABH,-2.00133,0.100394,0.00645389,0.63826 kka2_1:8_K112V,kka2_1:8_112,Kka2,kka2_1:8,P00552,,YES,112,K,V,KV,PositiveCharge,Hydrophobic,9.74,5.60847,-4.13153,97,146,117,-29,168.6,140,-28.6,-2.491,-2.276,-0.215,,0.076,H,A,1.3,-1.37,10.58,10.58,56.06,ABH,-2.00133,0.100394,0.00645389,0.63826 kka2_1:8_K138A,kka2_1:8_138,Kka2,kka2_1:8,P00552,,YES,138,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-2.5,-2.407,-0.093,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.100394,0.00628542,0.81766 kka2_1:8_K138A,kka2_1:8_138,Kka2,kka2_1:8,P00552,,YES,138,K,A,KA,PositiveCharge,Hydrophobic,9.74,6,-3.74,106,146,89,-57,168.6,88.6,-80,-2.5,-2.407,-0.093,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.100394,0.00628542,0.81766 kka2_1:8_K138P,kka2_1:8_138,Kka2,kka2_1:8,P00552,,YES,138,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-2.5,-3.19,0.69,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.100394,0.00628542,0.710223 kka2_1:8_K138P,kka2_1:8_138,Kka2,kka2_1:8,P00552,,YES,138,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-2.5,-3.19,0.69,,0.594,H,A,2.34,0.98,1.356,,71.59,HBB,-2.48833,0.100394,0.00628542,0.710223 kka2_1:8_K175F,kka2_1:8_175,Kka2,kka2_1:8,P00552,,YES,175,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-2.897,-4.186,1.289,,0.579,H,A,2.34,0.51,15.316,15.316,71.59,HBH,-1.82333,0.100394,0.00693093,0.785124 kka2_1:8_K175F,kka2_1:8_175,Kka2,kka2_1:8,P00552,,YES,175,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-2.897,-4.186,1.289,,0.579,H,A,2.34,0.51,15.316,15.316,71.59,HBH,-1.82333,0.100394,0.00693093,0.785124 kka2_1:8_K175L,kka2_1:8_175,Kka2,kka2_1:8,P00552,,YES,175,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-2.897,-1.898,-0.999,,0.579,H,A,2.34,0.51,15.316,15.316,71.59,HBH,-1.82333,0.100394,0.00693093,0.971025 kka2_1:8_K175L,kka2_1:8_175,Kka2,kka2_1:8,P00552,,YES,175,K,L,KL,PositiveCharge,Hydrophobic,9.74,9.7088,-0.0312033,107,146,131,-15,168.6,166.7,-1.9,-2.897,-1.898,-0.999,,0.579,H,A,2.34,0.51,15.316,15.316,71.59,HBH,-1.82333,0.100394,0.00693093,0.971025 kka2_1:8_K175W,kka2_1:8_175,Kka2,kka2_1:8,P00552,,YES,175,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-2.897,-5.429,2.532,,0.579,H,A,2.34,0.51,15.316,15.316,71.59,HBH,-1.82333,0.100394,0.00693093,0.831006 kka2_1:8_K175W,kka2_1:8_175,Kka2,kka2_1:8,P00552,,YES,175,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-2.897,-5.429,2.532,,0.579,H,A,2.34,0.51,15.316,15.316,71.59,HBH,-1.82333,0.100394,0.00693093,0.831006 kka2_1:8_K50C,kka2_1:8_50,Kka2,kka2_1:8,P00552,,YES,50,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-0.833,-5.139,4.306,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.100394,0.00138626,0.502108 kka2_1:8_K50C,kka2_1:8_50,Kka2,kka2_1:8,P00552,,YES,50,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-0.833,-5.139,4.306,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.100394,0.00138626,0.502108 kka2_1:8_K50F,kka2_1:8_50,Kka2,kka2_1:8,P00552,,YES,50,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-0.833,-4.344,3.511,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.100394,0.00138626,0.420216 kka2_1:8_K50F,kka2_1:8_50,Kka2,kka2_1:8,P00552,,YES,50,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-0.833,-4.344,3.511,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.100394,0.00138626,0.420216 kka2_1:8_K50G,kka2_1:8_50,Kka2,kka2_1:8,P00552,,YES,50,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-0.833,-3.41,2.577,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.100394,0.00138626,0.501341 kka2_1:8_K50G,kka2_1:8_50,Kka2,kka2_1:8,P00552,,YES,50,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-0.833,-3.41,2.577,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.100394,0.00138626,0.501341 kka2_1:8_K50M,kka2_1:8_50,Kka2,kka2_1:8,P00552,,YES,50,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-0.833,-4.531,3.698,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.100394,0.00138626,0.432874 kka2_1:8_K50M,kka2_1:8_50,Kka2,kka2_1:8,P00552,,YES,50,K,M,KM,PositiveCharge,Hydrophobic,9.74,5.74,-4,95,146,149,3,168.6,162.9,-5.7,-0.833,-4.531,3.698,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.100394,0.00138626,0.432874 kka2_1:8_K50P,kka2_1:8_50,Kka2,kka2_1:8,P00552,,YES,50,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-0.833,-3.727,2.894,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.100394,0.00138626,0.462259 kka2_1:8_K50P,kka2_1:8_50,Kka2,kka2_1:8,P00552,,YES,50,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-0.833,-3.727,2.894,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.100394,0.00138626,0.462259 kka2_1:8_K50W,kka2_1:8_50,Kka2,kka2_1:8,P00552,,YES,50,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-0.833,-5.374,4.541,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.100394,0.00138626,0.393929 kka2_1:8_K50W,kka2_1:8_50,Kka2,kka2_1:8,P00552,,YES,50,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-0.833,-5.374,4.541,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.100394,0.00138626,0.393929 kka2_1:8_K50Y,kka2_1:8_50,Kka2,kka2_1:8,P00552,,YES,50,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-0.833,-4.214,3.381,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.100394,0.00138626,0.435214 kka2_1:8_K50Y,kka2_1:8_50,Kka2,kka2_1:8,P00552,,YES,50,K,Y,KY,PositiveCharge,Hydrophobic,9.74,5.66,-4.08,85,146,181,35,168.6,193.6,25,-0.833,-4.214,3.381,,0.117,E,B,2.34,-0.39,0.758,,16.67,HBP,-1.54867,0.100394,0.00138626,0.435214 kka2_1:8_L102A,kka2_1:8_102,Kka2,kka2_1:8,P00552,,YES,102,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.804,-3.129,2.325,,,T,A,1.59,-1.17,0.97,,42.42,AHH,-1.398,0.100394,0.00201332,0.474348 kka2_1:8_L102A,kka2_1:8_102,Kka2,kka2_1:8,P00552,,YES,102,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.804,-3.129,2.325,,,T,A,1.59,-1.17,0.97,,42.42,AHH,-1.398,0.100394,0.00201332,0.474348 kka2_1:8_L102G,kka2_1:8_102,Kka2,kka2_1:8,P00552,,YES,102,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.804,-3.835,3.031,,,T,A,1.59,-1.17,0.97,,42.42,AHH,-1.398,0.100394,0.00201332,0.430419 kka2_1:8_L102G,kka2_1:8_102,Kka2,kka2_1:8,P00552,,YES,102,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.804,-3.835,3.031,,,T,A,1.59,-1.17,0.97,,42.42,AHH,-1.398,0.100394,0.00201332,0.430419 kka2_1:8_L102K,kka2_1:8_102,Kka2,kka2_1:8,P00552,,YES,102,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.804,-3.708,2.904,,,T,A,1.59,-1.17,0.97,,42.42,AHH,-1.398,0.100394,0.00201332,0.394047 kka2_1:8_L102K,kka2_1:8_102,Kka2,kka2_1:8,P00552,,YES,102,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.804,-3.708,2.904,,,T,A,1.59,-1.17,0.97,,42.42,AHH,-1.398,0.100394,0.00201332,0.394047 kka2_1:8_L102N,kka2_1:8_102,Kka2,kka2_1:8,P00552,,YES,102,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.804,-4.149,3.345,,,T,A,1.59,-1.17,0.97,,42.42,AHH,-1.398,0.100394,0.00201332,0.398136 kka2_1:8_L102N,kka2_1:8_102,Kka2,kka2_1:8,P00552,,YES,102,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.804,-4.149,3.345,,,T,A,1.59,-1.17,0.97,,42.42,AHH,-1.398,0.100394,0.00201332,0.398136 kka2_1:8_L102T,kka2_1:8_102,Kka2,kka2_1:8,P00552,,YES,102,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.804,-3.473,2.669,,,T,A,1.59,-1.17,0.97,,42.42,AHH,-1.398,0.100394,0.00201332,0.472169 kka2_1:8_L102T,kka2_1:8_102,Kka2,kka2_1:8,P00552,,YES,102,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.804,-3.473,2.669,,,T,A,1.59,-1.17,0.97,,42.42,AHH,-1.398,0.100394,0.00201332,0.472169 kka2_1:8_L102W,kka2_1:8_102,Kka2,kka2_1:8,P00552,,YES,102,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.804,-5.124,4.32,,,T,A,1.59,-1.17,0.97,,42.42,AHH,-1.398,0.100394,0.00201332,0.375405 kka2_1:8_L102W,kka2_1:8_102,Kka2,kka2_1:8,P00552,,YES,102,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.804,-5.124,4.32,,,T,A,1.59,-1.17,0.97,,42.42,AHH,-1.398,0.100394,0.00201332,0.375405 kka2_1:8_L103E,kka2_1:8_103,Kka2,kka2_1:8,P00552,,YES,103,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-2.362,-2.689,0.327,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.100394,0.00574792,0.62312 kka2_1:8_L103E,kka2_1:8_103,Kka2,kka2_1:8,P00552,,YES,103,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-2.362,-2.689,0.327,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.100394,0.00574792,0.62312 kka2_1:8_L103S,kka2_1:8_103,Kka2,kka2_1:8,P00552,,YES,103,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-2.362,-2.565,0.203,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.100394,0.00574792,0.65564 kka2_1:8_L103S,kka2_1:8_103,Kka2,kka2_1:8,P00552,,YES,103,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-2.362,-2.565,0.203,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.100394,0.00574792,0.65564 kka2_1:8_L103Y,kka2_1:8_103,Kka2,kka2_1:8,P00552,,YES,103,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-2.362,-4.297,1.935,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.100394,0.00574792,0.617146 kka2_1:8_L103Y,kka2_1:8_103,Kka2,kka2_1:8,P00552,,YES,103,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-2.362,-4.297,1.935,,0.394,T,A,1.59,-0.99,3.499,,63.64,HHP,-1.534,0.100394,0.00574792,0.617146 kka2_1:8_L107G,kka2_1:8_107,Kka2,kka2_1:8,P00552,,YES,107,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.238,-3.822,2.584,,0.197,.,B,0.55,-1.1,4.478,,71.59,BHH,-2.143,0.100394,0.00561937,0.455231 kka2_1:8_L107G,kka2_1:8_107,Kka2,kka2_1:8,P00552,,YES,107,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.238,-3.822,2.584,,0.197,.,B,0.55,-1.1,4.478,,71.59,BHH,-2.143,0.100394,0.00561937,0.455231 kka2_1:8_L123C,kka2_1:8_123,Kka2,kka2_1:8,P00552,,YES,123,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.888,-4.72,3.832,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.100394,0.00325188,0.513044 kka2_1:8_L123C,kka2_1:8_123,Kka2,kka2_1:8,P00552,,YES,123,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.888,-4.72,3.832,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.100394,0.00325188,0.513044 kka2_1:8_L123D,kka2_1:8_123,Kka2,kka2_1:8,P00552,,YES,123,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.888,-4.173,3.285,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.100394,0.00325188,0.41184 kka2_1:8_L123D,kka2_1:8_123,Kka2,kka2_1:8,P00552,,YES,123,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.888,-4.173,3.285,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.100394,0.00325188,0.41184 kka2_1:8_L123E,kka2_1:8_123,Kka2,kka2_1:8,P00552,,YES,123,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.888,-3.94,3.052,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.100394,0.00325188,0.394101 kka2_1:8_L123E,kka2_1:8_123,Kka2,kka2_1:8,P00552,,YES,123,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.888,-3.94,3.052,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.100394,0.00325188,0.394101 kka2_1:8_L123F,kka2_1:8_123,Kka2,kka2_1:8,P00552,,YES,123,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.888,-3.7,2.812,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.100394,0.00325188,0.390504 kka2_1:8_L123F,kka2_1:8_123,Kka2,kka2_1:8,P00552,,YES,123,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.888,-3.7,2.812,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.100394,0.00325188,0.390504 kka2_1:8_L123G,kka2_1:8_123,Kka2,kka2_1:8,P00552,,YES,123,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.888,-3.859,2.971,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.100394,0.00325188,0.462822 kka2_1:8_L123G,kka2_1:8_123,Kka2,kka2_1:8,P00552,,YES,123,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.888,-3.859,2.971,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.100394,0.00325188,0.462822 kka2_1:8_L123K,kka2_1:8_123,Kka2,kka2_1:8,P00552,,YES,123,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.888,-3.75,2.862,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.100394,0.00325188,0.4009 kka2_1:8_L123K,kka2_1:8_123,Kka2,kka2_1:8,P00552,,YES,123,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.888,-3.75,2.862,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.100394,0.00325188,0.4009 kka2_1:8_L123N,kka2_1:8_123,Kka2,kka2_1:8,P00552,,YES,123,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.888,-4.173,3.285,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.100394,0.00325188,0.391477 kka2_1:8_L123N,kka2_1:8_123,Kka2,kka2_1:8,P00552,,YES,123,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.888,-4.173,3.285,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.100394,0.00325188,0.391477 kka2_1:8_L123T,kka2_1:8_123,Kka2,kka2_1:8,P00552,,YES,123,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.888,-3.505,2.617,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.100394,0.00325188,0.47193 kka2_1:8_L123T,kka2_1:8_123,Kka2,kka2_1:8,P00552,,YES,123,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.888,-3.505,2.617,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.100394,0.00325188,0.47193 kka2_1:8_L123Y,kka2_1:8_123,Kka2,kka2_1:8,P00552,,YES,123,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.888,-4.021,3.133,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.100394,0.00325188,0.394877 kka2_1:8_L123Y,kka2_1:8_123,Kka2,kka2_1:8,P00552,,YES,123,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.888,-4.021,3.133,,0.007,H,A,0.55,-0.4,0.389,,48.86,BHB,-1.301,0.100394,0.00325188,0.394877 kka2_1:8_L126C,kka2_1:8_126,Kka2,kka2_1:8,P00552,,YES,126,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.246,-4.83,3.584,,0.285,S,B,1.59,0.12,4.443,,51.89,PHA,-1.744,0.100394,0.0066485,0.520571 kka2_1:8_L126C,kka2_1:8_126,Kka2,kka2_1:8,P00552,,YES,126,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.246,-4.83,3.584,,0.285,S,B,1.59,0.12,4.443,,51.89,PHA,-1.744,0.100394,0.0066485,0.520571 kka2_1:8_L126D,kka2_1:8_126,Kka2,kka2_1:8,P00552,,YES,126,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.246,-4.074,2.828,,0.285,S,B,1.59,0.12,4.443,,51.89,PHA,-1.744,0.100394,0.0066485,0.412908 kka2_1:8_L126D,kka2_1:8_126,Kka2,kka2_1:8,P00552,,YES,126,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.246,-4.074,2.828,,0.285,S,B,1.59,0.12,4.443,,51.89,PHA,-1.744,0.100394,0.0066485,0.412908 kka2_1:8_L126K,kka2_1:8_126,Kka2,kka2_1:8,P00552,,YES,126,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.246,-3.81,2.564,,0.285,S,B,1.59,0.12,4.443,,51.89,PHA,-1.744,0.100394,0.0066485,0.423278 kka2_1:8_L126K,kka2_1:8_126,Kka2,kka2_1:8,P00552,,YES,126,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.246,-3.81,2.564,,0.285,S,B,1.59,0.12,4.443,,51.89,PHA,-1.744,0.100394,0.0066485,0.423278 kka2_1:8_L126N,kka2_1:8_126,Kka2,kka2_1:8,P00552,,YES,126,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.246,-4.157,2.911,,0.285,S,B,1.59,0.12,4.443,,51.89,PHA,-1.744,0.100394,0.0066485,0.413942 kka2_1:8_L126N,kka2_1:8_126,Kka2,kka2_1:8,P00552,,YES,126,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.246,-4.157,2.911,,0.285,S,B,1.59,0.12,4.443,,51.89,PHA,-1.744,0.100394,0.0066485,0.413942 kka2_1:8_L126T,kka2_1:8_126,Kka2,kka2_1:8,P00552,,YES,126,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.246,-2.585,1.339,,0.285,S,B,1.59,0.12,4.443,,51.89,PHA,-1.744,0.100394,0.0066485,0.532366 kka2_1:8_L126T,kka2_1:8_126,Kka2,kka2_1:8,P00552,,YES,126,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.246,-2.585,1.339,,0.285,S,B,1.59,0.12,4.443,,51.89,PHA,-1.744,0.100394,0.0066485,0.532366 kka2_1:8_L126Y,kka2_1:8_126,Kka2,kka2_1:8,P00552,,YES,126,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.246,-4.126,2.88,,0.285,S,B,1.59,0.12,4.443,,51.89,PHA,-1.744,0.100394,0.0066485,0.443232 kka2_1:8_L126Y,kka2_1:8_126,Kka2,kka2_1:8,P00552,,YES,126,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.246,-4.126,2.88,,0.285,S,B,1.59,0.12,4.443,,51.89,PHA,-1.744,0.100394,0.0066485,0.443232 kka2_1:8_L152A,kka2_1:8_152,Kka2,kka2_1:8,P00552,,YES,152,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.521,-2.279,0.758,,0.547,.,A,0.55,1.36,1.442,,63.64,OHH,-1.162,0.100394,0.00674868,0.670955 kka2_1:8_L152A,kka2_1:8_152,Kka2,kka2_1:8,P00552,,YES,152,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.521,-2.279,0.758,,0.547,.,A,0.55,1.36,1.442,,63.64,OHH,-1.162,0.100394,0.00674868,0.670955 kka2_1:8_L152C,kka2_1:8_152,Kka2,kka2_1:8,P00552,,YES,152,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.521,-4.941,3.42,,0.547,.,A,0.55,1.36,1.442,,63.64,OHH,-1.162,0.100394,0.00674868,0.66916 kka2_1:8_L152C,kka2_1:8_152,Kka2,kka2_1:8,P00552,,YES,152,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.521,-4.941,3.42,,0.547,.,A,0.55,1.36,1.442,,63.64,OHH,-1.162,0.100394,0.00674868,0.66916 kka2_1:8_L152G,kka2_1:8_152,Kka2,kka2_1:8,P00552,,YES,152,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.521,-3.713,2.192,,0.547,.,A,0.55,1.36,1.442,,63.64,OHH,-1.162,0.100394,0.00674868,0.643146 kka2_1:8_L152G,kka2_1:8_152,Kka2,kka2_1:8,P00552,,YES,152,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.521,-3.713,2.192,,0.547,.,A,0.55,1.36,1.442,,63.64,OHH,-1.162,0.100394,0.00674868,0.643146 kka2_1:8_L152S,kka2_1:8_152,Kka2,kka2_1:8,P00552,,YES,152,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.521,-3.591,2.07,,0.547,.,A,0.55,1.36,1.442,,63.64,OHH,-1.162,0.100394,0.00674868,0.66076 kka2_1:8_L152S,kka2_1:8_152,Kka2,kka2_1:8,P00552,,YES,152,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.521,-3.591,2.07,,0.547,.,A,0.55,1.36,1.442,,63.64,OHH,-1.162,0.100394,0.00674868,0.66076 kka2_1:8_L152Y,kka2_1:8_152,Kka2,kka2_1:8,P00552,,YES,152,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.521,-4.238,2.717,,0.547,.,A,0.55,1.36,1.442,,63.64,OHH,-1.162,0.100394,0.00674868,0.574924 kka2_1:8_L152Y,kka2_1:8_152,Kka2,kka2_1:8,P00552,,YES,152,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.521,-4.238,2.717,,0.547,.,A,0.55,1.36,1.442,,63.64,OHH,-1.162,0.100394,0.00674868,0.574924 kka2_1:8_L158C,kka2_1:8_158,Kka2,kka2_1:8,P00552,,YES,158,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.947,-4.909,2.962,,0.095,.,B,0.55,0.77,1.607,,63.64,AHA,-1.25333,0.100394,0.00529068,0.679738 kka2_1:8_L158C,kka2_1:8_158,Kka2,kka2_1:8,P00552,,YES,158,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.947,-4.909,2.962,,0.095,.,B,0.55,0.77,1.607,,63.64,AHA,-1.25333,0.100394,0.00529068,0.679738 kka2_1:8_L158S,kka2_1:8_158,Kka2,kka2_1:8,P00552,,YES,158,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.947,-3.691,1.744,,0.095,.,B,0.55,0.77,1.607,,63.64,AHA,-1.25333,0.100394,0.00529068,0.495916 kka2_1:8_L158S,kka2_1:8_158,Kka2,kka2_1:8,P00552,,YES,158,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.947,-3.691,1.744,,0.095,.,B,0.55,0.77,1.607,,63.64,AHA,-1.25333,0.100394,0.00529068,0.495916 kka2_1:8_L158T,kka2_1:8_158,Kka2,kka2_1:8,P00552,,YES,158,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.947,-3.635,1.688,,0.095,.,B,0.55,0.77,1.607,,63.64,AHA,-1.25333,0.100394,0.00529068,0.504595 kka2_1:8_L158T,kka2_1:8_158,Kka2,kka2_1:8,P00552,,YES,158,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.947,-3.635,1.688,,0.095,.,B,0.55,0.77,1.607,,63.64,AHA,-1.25333,0.100394,0.00529068,0.504595 kka2_1:8_L165W,kka2_1:8_165,Kka2,kka2_1:8,P00552,,YES,165,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-2.453,-3.283,0.83,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.100394,0.00801161,0.780875 kka2_1:8_L165W,kka2_1:8_165,Kka2,kka2_1:8,P00552,,YES,165,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-2.453,-3.283,0.83,,0.299,.,B,0.55,1.12,10.622,10.622,64.39,OHH,-1.90967,0.100394,0.00801161,0.780875 kka2_1:8_L170D,kka2_1:8_170,Kka2,kka2_1:8,P00552,,YES,170,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.28,-4.131,2.851,,0.029,H,A,1.59,0.11,1.453,,62.5,AHH,-1.534,0.100394,0.00730791,0.443992 kka2_1:8_L170D,kka2_1:8_170,Kka2,kka2_1:8,P00552,,YES,170,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.28,-4.131,2.851,,0.029,H,A,1.59,0.11,1.453,,62.5,AHH,-1.534,0.100394,0.00730791,0.443992 kka2_1:8_L174W,kka2_1:8_174,Kka2,kka2_1:8,P00552,,YES,174,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.952,-5.22,4.268,,,H,A,1.59,-0.31,1.204,,51.89,BHB,-2.08533,0.100394,0.00438501,0.412914 kka2_1:8_L174W,kka2_1:8_174,Kka2,kka2_1:8,P00552,,YES,174,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.952,-5.22,4.268,,,H,A,1.59,-0.31,1.204,,51.89,BHB,-2.08533,0.100394,0.00438501,0.412914 kka2_1:8_L19A,kka2_1:8_19,Kka2,kka2_1:8,P00552,,YES,19,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.254,-3.301,2.047,,0.08,T,A,1.59,-0.26,2.044,,65.53,BHH,-2.221,0.100394,0.00620703,0.447138 kka2_1:8_L19A,kka2_1:8_19,Kka2,kka2_1:8,P00552,,YES,19,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.254,-3.301,2.047,,0.08,T,A,1.59,-0.26,2.044,,65.53,BHH,-2.221,0.100394,0.00620703,0.447138 kka2_1:8_L19D,kka2_1:8_19,Kka2,kka2_1:8,P00552,,YES,19,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.254,-4.151,2.897,,0.08,T,A,1.59,-0.26,2.044,,65.53,BHH,-2.221,0.100394,0.00620703,0.427001 kka2_1:8_L19D,kka2_1:8_19,Kka2,kka2_1:8,P00552,,YES,19,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.254,-4.151,2.897,,0.08,T,A,1.59,-0.26,2.044,,65.53,BHH,-2.221,0.100394,0.00620703,0.427001 kka2_1:8_L19E,kka2_1:8_19,Kka2,kka2_1:8,P00552,,YES,19,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.254,-3.966,2.712,,0.08,T,A,1.59,-0.26,2.044,,65.53,BHH,-2.221,0.100394,0.00620703,0.412365 kka2_1:8_L19E,kka2_1:8_19,Kka2,kka2_1:8,P00552,,YES,19,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.254,-3.966,2.712,,0.08,T,A,1.59,-0.26,2.044,,65.53,BHH,-2.221,0.100394,0.00620703,0.412365 kka2_1:8_L19Y,kka2_1:8_19,Kka2,kka2_1:8,P00552,,YES,19,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.254,-2.672,1.418,,0.08,T,A,1.59,-0.26,2.044,,65.53,BHH,-2.221,0.100394,0.00620703,0.543593 kka2_1:8_L19Y,kka2_1:8_19,Kka2,kka2_1:8,P00552,,YES,19,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.254,-2.672,1.418,,0.08,T,A,1.59,-0.26,2.044,,65.53,BHH,-2.221,0.100394,0.00620703,0.543593 kka2_1:8_L212G,kka2_1:8_212,Kka2,kka2_1:8,P00552,,YES,212,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.904,-3.697,2.793,,,,B,1.59,-0.78,1.708,,42.42,BHO,-0.799667,0.100394,0.0031426,0.449826 kka2_1:8_L212G,kka2_1:8_212,Kka2,kka2_1:8,P00552,,YES,212,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.904,-3.697,2.793,,,,B,1.59,-0.78,1.708,,42.42,BHO,-0.799667,0.100394,0.0031426,0.449826 kka2_1:8_L223E,kka2_1:8_223,Kka2,kka2_1:8,P00552,,YES,223,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.861,-3.963,3.102,,,H,A,1.59,-1.24,1.017,,50,HHH,-0.854333,0.100394,0.00253574,0.390619 kka2_1:8_L223E,kka2_1:8_223,Kka2,kka2_1:8,P00552,,YES,223,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.861,-3.963,3.102,,,H,A,1.59,-1.24,1.017,,50,HHH,-0.854333,0.100394,0.00253574,0.390619 kka2_1:8_L241A,kka2_1:8_241,Kka2,kka2_1:8,P00552,,YES,241,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.158,-3.226,2.068,,0.08,H,A,1.59,-0.82,1.136,,63.26,HHH,-1.58533,0.100394,0.0117299,0.466765 kka2_1:8_L241A,kka2_1:8_241,Kka2,kka2_1:8,P00552,,YES,241,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.158,-3.226,2.068,,0.08,H,A,1.59,-0.82,1.136,,63.26,HHH,-1.58533,0.100394,0.0117299,0.466765 kka2_1:8_L241S,kka2_1:8_241,Kka2,kka2_1:8,P00552,,YES,241,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.158,-3.689,2.531,,0.08,H,A,1.59,-0.82,1.136,,63.26,HHH,-1.58533,0.100394,0.0117299,0.471869 kka2_1:8_L241S,kka2_1:8_241,Kka2,kka2_1:8,P00552,,YES,241,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.158,-3.689,2.531,,0.08,H,A,1.59,-0.82,1.136,,63.26,HHH,-1.58533,0.100394,0.0117299,0.471869 kka2_1:8_L243D,kka2_1:8_243,Kka2,kka2_1:8,P00552,,YES,243,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-2.651,-3.837,1.186,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.100394,0.00884927,0.541447 kka2_1:8_L243D,kka2_1:8_243,Kka2,kka2_1:8,P00552,,YES,243,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-2.651,-3.837,1.186,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.100394,0.00884927,0.541447 kka2_1:8_L243S,kka2_1:8_243,Kka2,kka2_1:8,P00552,,YES,243,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-2.651,-2.842,0.191,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.100394,0.00884927,0.699623 kka2_1:8_L243S,kka2_1:8_243,Kka2,kka2_1:8,P00552,,YES,243,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-2.651,-2.842,0.191,,0.277,H,A,0.55,-0.67,1.708,,92.05,HHH,-2.03767,0.100394,0.00884927,0.699623 kka2_1:8_L260Y,kka2_1:8_260,Kka2,kka2_1:8,P00552,,YES,260,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.741,-3.966,3.225,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.100394,0.0233782,0.355748 kka2_1:8_L260Y,kka2_1:8_260,Kka2,kka2_1:8,P00552,,YES,260,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.741,-3.966,3.225,,0.022,H,A,1.59,-0.52,,,,HHA,-0.845667,0.100394,0.0233782,0.355748 kka2_1:8_L39C,kka2_1:8_39,Kka2,kka2_1:8,P00552,,YES,39,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.223,-4.817,3.594,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.100394,0.00493618,0.532221 kka2_1:8_L39C,kka2_1:8_39,Kka2,kka2_1:8,P00552,,YES,39,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.223,-4.817,3.594,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.100394,0.00493618,0.532221 kka2_1:8_L39F,kka2_1:8_39,Kka2,kka2_1:8,P00552,,YES,39,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.223,-2.955,1.732,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.100394,0.00493618,0.533679 kka2_1:8_L39F,kka2_1:8_39,Kka2,kka2_1:8,P00552,,YES,39,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.223,-2.955,1.732,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.100394,0.00493618,0.533679 kka2_1:8_L39S,kka2_1:8_39,Kka2,kka2_1:8,P00552,,YES,39,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.223,-3.678,2.455,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.100394,0.00493618,0.457564 kka2_1:8_L39S,kka2_1:8_39,Kka2,kka2_1:8,P00552,,YES,39,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.223,-3.678,2.455,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.100394,0.00493618,0.457564 kka2_1:8_L39T,kka2_1:8_39,Kka2,kka2_1:8,P00552,,YES,39,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.223,-3.551,2.328,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.100394,0.00493618,0.50111 kka2_1:8_L39T,kka2_1:8_39,Kka2,kka2_1:8,P00552,,YES,39,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.223,-3.551,2.328,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.100394,0.00493618,0.50111 kka2_1:8_L39Y,kka2_1:8_39,Kka2,kka2_1:8,P00552,,YES,39,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.223,-4.042,2.819,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.100394,0.00493618,0.416253 kka2_1:8_L39Y,kka2_1:8_39,Kka2,kka2_1:8,P00552,,YES,39,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.223,-4.042,2.819,,,E,B,1.59,-1.21,2.761,,71.59,BHP,-1.69167,0.100394,0.00493618,0.416253 kka2_1:8_L53A,kka2_1:8_53,Kka2,kka2_1:8,P00552,,YES,53,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-2.681,-2.486,-0.195,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.100394,0.00671168,0.875255 kka2_1:8_L53A,kka2_1:8_53,Kka2,kka2_1:8,P00552,,YES,53,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-2.681,-2.486,-0.195,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.100394,0.00671168,0.875255 kka2_1:8_L53G,kka2_1:8_53,Kka2,kka2_1:8,P00552,,YES,53,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-2.681,-3.649,0.968,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.100394,0.00671168,0.775064 kka2_1:8_L53G,kka2_1:8_53,Kka2,kka2_1:8,P00552,,YES,53,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-2.681,-3.649,0.968,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.100394,0.00671168,0.775064 kka2_1:8_L53N,kka2_1:8_53,Kka2,kka2_1:8,P00552,,YES,53,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-2.681,-3.274,0.593,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.100394,0.00671168,0.809064 kka2_1:8_L53N,kka2_1:8_53,Kka2,kka2_1:8,P00552,,YES,53,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-2.681,-3.274,0.593,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.100394,0.00671168,0.809064 kka2_1:8_L53T,kka2_1:8_53,Kka2,kka2_1:8,P00552,,YES,53,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-2.681,-3.105,0.424,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.100394,0.00671168,0.778139 kka2_1:8_L53T,kka2_1:8_53,Kka2,kka2_1:8,P00552,,YES,53,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-2.681,-3.105,0.424,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.100394,0.00671168,0.778139 kka2_1:8_L53W,kka2_1:8_53,Kka2,kka2_1:8,P00552,,YES,53,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-2.681,-5.633,2.952,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.100394,0.00671168,0.86581 kka2_1:8_L53W,kka2_1:8_53,Kka2,kka2_1:8,P00552,,YES,53,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-2.681,-5.633,2.952,,0.569,E,B,0.55,0.8,1.18,,71.59,AHP,-2.47433,0.100394,0.00671168,0.86581 kka2_1:8_L57C,kka2_1:8_57,Kka2,kka2_1:8,P00552,,YES,57,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.898,-5.037,3.139,,0.343,T,A,0.55,0.98,13.359,13.359,52.65,HHP,-2.20733,0.100394,0.00723769,0.598247 kka2_1:8_L57C,kka2_1:8_57,Kka2,kka2_1:8,P00552,,YES,57,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.898,-5.037,3.139,,0.343,T,A,0.55,0.98,13.359,13.359,52.65,HHP,-2.20733,0.100394,0.00723769,0.598247 kka2_1:8_L57F,kka2_1:8_57,Kka2,kka2_1:8,P00552,,YES,57,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.898,-1.677,-0.221,,0.343,T,A,0.55,0.98,13.359,13.359,52.65,HHP,-2.20733,0.100394,0.00723769,0.802782 kka2_1:8_L57F,kka2_1:8_57,Kka2,kka2_1:8,P00552,,YES,57,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.898,-1.677,-0.221,,0.343,T,A,0.55,0.98,13.359,13.359,52.65,HHP,-2.20733,0.100394,0.00723769,0.802782 kka2_1:8_L57G,kka2_1:8_57,Kka2,kka2_1:8,P00552,,YES,57,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.898,-3.786,1.888,,0.343,T,A,0.55,0.98,13.359,13.359,52.65,HHP,-2.20733,0.100394,0.00723769,0.498513 kka2_1:8_L57G,kka2_1:8_57,Kka2,kka2_1:8,P00552,,YES,57,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.898,-3.786,1.888,,0.343,T,A,0.55,0.98,13.359,13.359,52.65,HHP,-2.20733,0.100394,0.00723769,0.498513 kka2_1:8_L57S,kka2_1:8_57,Kka2,kka2_1:8,P00552,,YES,57,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.898,-3.77,1.872,,0.343,T,A,0.55,0.98,13.359,13.359,52.65,HHP,-2.20733,0.100394,0.00723769,0.503326 kka2_1:8_L57S,kka2_1:8_57,Kka2,kka2_1:8,P00552,,YES,57,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.898,-3.77,1.872,,0.343,T,A,0.55,0.98,13.359,13.359,52.65,HHP,-2.20733,0.100394,0.00723769,0.503326 kka2_1:8_L57Y,kka2_1:8_57,Kka2,kka2_1:8,P00552,,YES,57,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.898,-2.955,1.057,,0.343,T,A,0.55,0.98,13.359,13.359,52.65,HHP,-2.20733,0.100394,0.00723769,0.57509 kka2_1:8_L57Y,kka2_1:8_57,Kka2,kka2_1:8,P00552,,YES,57,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.898,-2.955,1.057,,0.343,T,A,0.55,0.98,13.359,13.359,52.65,HHP,-2.20733,0.100394,0.00723769,0.57509 kka2_1:8_L60E,kka2_1:8_60,Kka2,kka2_1:8,P00552,,YES,60,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.997,-3.964,2.967,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.100394,0.00262176,0.455153 kka2_1:8_L60E,kka2_1:8_60,Kka2,kka2_1:8,P00552,,YES,60,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.997,-3.964,2.967,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.100394,0.00262176,0.455153 kka2_1:8_L60F,kka2_1:8_60,Kka2,kka2_1:8,P00552,,YES,60,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.997,-2.839,1.842,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.100394,0.00262176,0.518066 kka2_1:8_L60F,kka2_1:8_60,Kka2,kka2_1:8,P00552,,YES,60,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-0.997,-2.839,1.842,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.100394,0.00262176,0.518066 kka2_1:8_L60N,kka2_1:8_60,Kka2,kka2_1:8,P00552,,YES,60,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.997,-4.225,3.228,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.100394,0.00262176,0.434179 kka2_1:8_L60N,kka2_1:8_60,Kka2,kka2_1:8,P00552,,YES,60,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.997,-4.225,3.228,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.100394,0.00262176,0.434179 kka2_1:8_L60T,kka2_1:8_60,Kka2,kka2_1:8,P00552,,YES,60,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.997,-3.529,2.532,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.100394,0.00262176,0.48634 kka2_1:8_L60T,kka2_1:8_60,Kka2,kka2_1:8,P00552,,YES,60,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.997,-3.529,2.532,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.100394,0.00262176,0.48634 kka2_1:8_L60W,kka2_1:8_60,Kka2,kka2_1:8,P00552,,YES,60,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.997,-5.166,4.169,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.100394,0.00262176,0.412464 kka2_1:8_L60W,kka2_1:8_60,Kka2,kka2_1:8,P00552,,YES,60,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.997,-5.166,4.169,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.100394,0.00262176,0.412464 kka2_1:8_L60Y,kka2_1:8_60,Kka2,kka2_1:8,P00552,,YES,60,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.997,-3.955,2.958,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.100394,0.00262176,0.462418 kka2_1:8_L60Y,kka2_1:8_60,Kka2,kka2_1:8,P00552,,YES,60,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.997,-3.955,2.958,,0.095,H,A,0.55,-0.01,1.405,,48.48,AHP,-1.64367,0.100394,0.00262176,0.462418 kka2_1:8_L67C,kka2_1:8_67,Kka2,kka2_1:8,P00552,,YES,67,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.741,-4.665,3.924,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.100394,0.00102787,0.444752 kka2_1:8_L67C,kka2_1:8_67,Kka2,kka2_1:8,P00552,,YES,67,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.741,-4.665,3.924,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.100394,0.00102787,0.444752 kka2_1:8_L67E,kka2_1:8_67,Kka2,kka2_1:8,P00552,,YES,67,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.741,-3.918,3.177,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.100394,0.00102787,0.359357 kka2_1:8_L67E,kka2_1:8_67,Kka2,kka2_1:8,P00552,,YES,67,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.741,-3.918,3.177,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.100394,0.00102787,0.359357 kka2_1:8_L67G,kka2_1:8_67,Kka2,kka2_1:8,P00552,,YES,67,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.741,-3.836,3.095,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.100394,0.00102787,0.404758 kka2_1:8_L67G,kka2_1:8_67,Kka2,kka2_1:8,P00552,,YES,67,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.741,-3.836,3.095,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.100394,0.00102787,0.404758 kka2_1:8_L67H,kka2_1:8_67,Kka2,kka2_1:8,P00552,,YES,67,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.741,-4.933,4.192,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.100394,0.00102787,0.386242 kka2_1:8_L67H,kka2_1:8_67,Kka2,kka2_1:8,P00552,,YES,67,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-0.741,-4.933,4.192,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.100394,0.00102787,0.386242 kka2_1:8_L67I,kka2_1:8_67,Kka2,kka2_1:8,P00552,,YES,67,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.741,-2.914,2.173,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.100394,0.00102787,0.445205 kka2_1:8_L67I,kka2_1:8_67,Kka2,kka2_1:8,P00552,,YES,67,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.741,-2.914,2.173,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.100394,0.00102787,0.445205 kka2_1:8_L67K,kka2_1:8_67,Kka2,kka2_1:8,P00552,,YES,67,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.741,-3.71,2.969,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.100394,0.00102787,0.361813 kka2_1:8_L67K,kka2_1:8_67,Kka2,kka2_1:8,P00552,,YES,67,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.741,-3.71,2.969,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.100394,0.00102787,0.361813 kka2_1:8_L67N,kka2_1:8_67,Kka2,kka2_1:8,P00552,,YES,67,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.741,-4.151,3.41,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.100394,0.00102787,0.365438 kka2_1:8_L67N,kka2_1:8_67,Kka2,kka2_1:8,P00552,,YES,67,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.741,-4.151,3.41,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.100394,0.00102787,0.365438 kka2_1:8_L67Q,kka2_1:8_67,Kka2,kka2_1:8,P00552,,YES,67,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.741,-4.153,3.412,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.100394,0.00102787,0.371506 kka2_1:8_L67Q,kka2_1:8_67,Kka2,kka2_1:8,P00552,,YES,67,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-0.741,-4.153,3.412,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.100394,0.00102787,0.371506 kka2_1:8_L67T,kka2_1:8_67,Kka2,kka2_1:8,P00552,,YES,67,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.741,-3.45,2.709,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.100394,0.00102787,0.41752 kka2_1:8_L67T,kka2_1:8_67,Kka2,kka2_1:8,P00552,,YES,67,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.741,-3.45,2.709,,0.007,H,A,0.55,-0.66,,,,BHP,-1.42867,0.100394,0.00102787,0.41752 kka2_1:8_L70D,kka2_1:8_70,Kka2,kka2_1:8,P00552,,YES,70,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.017,-4.187,3.17,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.100394,0.00411884,0.404881 kka2_1:8_L70D,kka2_1:8_70,Kka2,kka2_1:8,P00552,,YES,70,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.017,-4.187,3.17,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.100394,0.00411884,0.404881 kka2_1:8_L70E,kka2_1:8_70,Kka2,kka2_1:8,P00552,,YES,70,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.017,-3.949,2.932,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.100394,0.00411884,0.395813 kka2_1:8_L70E,kka2_1:8_70,Kka2,kka2_1:8,P00552,,YES,70,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.017,-3.949,2.932,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.100394,0.00411884,0.395813 kka2_1:8_L70G,kka2_1:8_70,Kka2,kka2_1:8,P00552,,YES,70,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.017,-3.868,2.851,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.100394,0.00411884,0.444047 kka2_1:8_L70G,kka2_1:8_70,Kka2,kka2_1:8,P00552,,YES,70,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.017,-3.868,2.851,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.100394,0.00411884,0.444047 kka2_1:8_L70H,kka2_1:8_70,Kka2,kka2_1:8,P00552,,YES,70,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.017,-4.982,3.965,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.100394,0.00411884,0.415054 kka2_1:8_L70H,kka2_1:8_70,Kka2,kka2_1:8,P00552,,YES,70,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.017,-4.982,3.965,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.100394,0.00411884,0.415054 kka2_1:8_L70N,kka2_1:8_70,Kka2,kka2_1:8,P00552,,YES,70,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.017,-4.199,3.182,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.100394,0.00411884,0.394994 kka2_1:8_L70N,kka2_1:8_70,Kka2,kka2_1:8,P00552,,YES,70,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.017,-4.199,3.182,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.100394,0.00411884,0.394994 kka2_1:8_L70S,kka2_1:8_70,Kka2,kka2_1:8,P00552,,YES,70,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.017,-3.687,2.67,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.100394,0.00411884,0.445366 kka2_1:8_L70S,kka2_1:8_70,Kka2,kka2_1:8,P00552,,YES,70,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.017,-3.687,2.67,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.100394,0.00411884,0.445366 kka2_1:8_L70T,kka2_1:8_70,Kka2,kka2_1:8,P00552,,YES,70,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.017,-3.534,2.517,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.100394,0.00411884,0.453943 kka2_1:8_L70T,kka2_1:8_70,Kka2,kka2_1:8,P00552,,YES,70,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.017,-3.534,2.517,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.100394,0.00411884,0.453943 kka2_1:8_L70W,kka2_1:8_70,Kka2,kka2_1:8,P00552,,YES,70,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.017,-5.201,4.184,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.100394,0.00411884,0.390925 kka2_1:8_L70W,kka2_1:8_70,Kka2,kka2_1:8,P00552,,YES,70,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.017,-5.201,4.184,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.100394,0.00411884,0.390925 kka2_1:8_L70Y,kka2_1:8_70,Kka2,kka2_1:8,P00552,,YES,70,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.017,-4.068,3.051,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.100394,0.00411884,0.401877 kka2_1:8_L70Y,kka2_1:8_70,Kka2,kka2_1:8,P00552,,YES,70,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.017,-4.068,3.051,,0.007,H,A,0.55,-0.43,1.791,,49.24,HHH,-1.23333,0.100394,0.00411884,0.401877 kka2_1:8_L7E,kka2_1:8_7,Kka2,kka2_1:8,P00552,,YES,7,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.926,-3.32,1.394,,,,,,,,,71.59,OHB,-2.12333,0.100394,0.00269456,0.969888 kka2_1:8_L7E,kka2_1:8_7,Kka2,kka2_1:8,P00552,,YES,7,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.926,-3.32,1.394,,,,,,,,,71.59,OHB,-2.12333,0.100394,0.00269456,0.969888 kka2_1:8_L7G,kka2_1:8_7,Kka2,kka2_1:8,P00552,,YES,7,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.926,-2.13,0.204,,,,,,,,,71.59,OHB,-2.12333,0.100394,0.00269456,0.97791 kka2_1:8_L7G,kka2_1:8_7,Kka2,kka2_1:8,P00552,,YES,7,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.926,-2.13,0.204,,,,,,,,,71.59,OHB,-2.12333,0.100394,0.00269456,0.97791 kka2_1:8_L7T,kka2_1:8_7,Kka2,kka2_1:8,P00552,,YES,7,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.926,-3.425,1.499,,,,,,,,,71.59,OHB,-2.12333,0.100394,0.00269456,0.991987 kka2_1:8_L7T,kka2_1:8_7,Kka2,kka2_1:8,P00552,,YES,7,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.926,-3.425,1.499,,,,,,,,,71.59,OHB,-2.12333,0.100394,0.00269456,0.991987 kka2_1:8_L81A,kka2_1:8_81,Kka2,kka2_1:8,P00552,,YES,81,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.427,-3.213,1.786,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.100394,0.00805839,0.550041 kka2_1:8_L81A,kka2_1:8_81,Kka2,kka2_1:8,P00552,,YES,81,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.427,-3.213,1.786,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.100394,0.00805839,0.550041 kka2_1:8_L81C,kka2_1:8_81,Kka2,kka2_1:8,P00552,,YES,81,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.427,-4.845,3.418,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.100394,0.00805839,0.72982 kka2_1:8_L81C,kka2_1:8_81,Kka2,kka2_1:8,P00552,,YES,81,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.427,-4.845,3.418,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.100394,0.00805839,0.72982 kka2_1:8_L81D,kka2_1:8_81,Kka2,kka2_1:8,P00552,,YES,81,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.427,-4.125,2.698,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.100394,0.00805839,0.622908 kka2_1:8_L81D,kka2_1:8_81,Kka2,kka2_1:8,P00552,,YES,81,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.427,-4.125,2.698,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.100394,0.00805839,0.622908 kka2_1:8_L81E,kka2_1:8_81,Kka2,kka2_1:8,P00552,,YES,81,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.427,-3.901,2.474,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.100394,0.00805839,0.623354 kka2_1:8_L81E,kka2_1:8_81,Kka2,kka2_1:8,P00552,,YES,81,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.427,-3.901,2.474,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.100394,0.00805839,0.623354 kka2_1:8_L81F,kka2_1:8_81,Kka2,kka2_1:8,P00552,,YES,81,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.427,-3.878,2.451,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.100394,0.00805839,0.628778 kka2_1:8_L81F,kka2_1:8_81,Kka2,kka2_1:8,P00552,,YES,81,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.427,-3.878,2.451,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.100394,0.00805839,0.628778 kka2_1:8_L81G,kka2_1:8_81,Kka2,kka2_1:8,P00552,,YES,81,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.427,-3.894,2.467,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.100394,0.00805839,0.650821 kka2_1:8_L81G,kka2_1:8_81,Kka2,kka2_1:8,P00552,,YES,81,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.427,-3.894,2.467,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.100394,0.00805839,0.650821 kka2_1:8_L81H,kka2_1:8_81,Kka2,kka2_1:8,P00552,,YES,81,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.427,-5.02,3.593,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.100394,0.00805839,0.65733 kka2_1:8_L81H,kka2_1:8_81,Kka2,kka2_1:8,P00552,,YES,81,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.427,-5.02,3.593,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.100394,0.00805839,0.65733 kka2_1:8_L81S,kka2_1:8_81,Kka2,kka2_1:8,P00552,,YES,81,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.427,-3.746,2.319,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.100394,0.00805839,0.650061 kka2_1:8_L81S,kka2_1:8_81,Kka2,kka2_1:8,P00552,,YES,81,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.427,-3.746,2.319,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.100394,0.00805839,0.650061 kka2_1:8_L81T,kka2_1:8_81,Kka2,kka2_1:8,P00552,,YES,81,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.427,-3.556,2.129,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.100394,0.00805839,0.651065 kka2_1:8_L81T,kka2_1:8_81,Kka2,kka2_1:8,P00552,,YES,81,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.427,-3.556,2.129,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.100394,0.00805839,0.651065 kka2_1:8_L81Y,kka2_1:8_81,Kka2,kka2_1:8,P00552,,YES,81,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.427,-4.125,2.698,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.100394,0.00805839,0.649035 kka2_1:8_L81Y,kka2_1:8_81,Kka2,kka2_1:8,P00552,,YES,81,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.427,-4.125,2.698,,0.46,E,A,0.55,-0.14,1.087,,63.64,HHA,-1.50567,0.100394,0.00805839,0.649035 kka2_1:8_L92A,kka2_1:8_92,Kka2,kka2_1:8,P00552,,YES,92,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.893,-3.128,2.235,,0.007,E,B,1.59,-0.19,1.719,,63.26,HHH,-0.962,0.100394,0.00307177,0.446921 kka2_1:8_L92A,kka2_1:8_92,Kka2,kka2_1:8,P00552,,YES,92,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-0.893,-3.128,2.235,,0.007,E,B,1.59,-0.19,1.719,,63.26,HHH,-0.962,0.100394,0.00307177,0.446921 kka2_1:8_L92C,kka2_1:8_92,Kka2,kka2_1:8,P00552,,YES,92,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.893,-4.72,3.827,,0.007,E,B,1.59,-0.19,1.719,,63.26,HHH,-0.962,0.100394,0.00307177,0.552782 kka2_1:8_L92C,kka2_1:8_92,Kka2,kka2_1:8,P00552,,YES,92,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.893,-4.72,3.827,,0.007,E,B,1.59,-0.19,1.719,,63.26,HHH,-0.962,0.100394,0.00307177,0.552782 kka2_1:8_L92D,kka2_1:8_92,Kka2,kka2_1:8,P00552,,YES,92,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.893,-4.173,3.28,,0.007,E,B,1.59,-0.19,1.719,,63.26,HHH,-0.962,0.100394,0.00307177,0.397611 kka2_1:8_L92D,kka2_1:8_92,Kka2,kka2_1:8,P00552,,YES,92,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.893,-4.173,3.28,,0.007,E,B,1.59,-0.19,1.719,,63.26,HHH,-0.962,0.100394,0.00307177,0.397611 kka2_1:8_L92G,kka2_1:8_92,Kka2,kka2_1:8,P00552,,YES,92,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.893,-3.838,2.945,,0.007,E,B,1.59,-0.19,1.719,,63.26,HHH,-0.962,0.100394,0.00307177,0.453328 kka2_1:8_L92G,kka2_1:8_92,Kka2,kka2_1:8,P00552,,YES,92,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.893,-3.838,2.945,,0.007,E,B,1.59,-0.19,1.719,,63.26,HHH,-0.962,0.100394,0.00307177,0.453328 kka2_1:8_L92I,kka2_1:8_92,Kka2,kka2_1:8,P00552,,YES,92,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.893,-2.953,2.06,,0.007,E,B,1.59,-0.19,1.719,,63.26,HHH,-0.962,0.100394,0.00307177,0.46009 kka2_1:8_L92I,kka2_1:8_92,Kka2,kka2_1:8,P00552,,YES,92,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-0.893,-2.953,2.06,,0.007,E,B,1.59,-0.19,1.719,,63.26,HHH,-0.962,0.100394,0.00307177,0.46009 kka2_1:8_L92K,kka2_1:8_92,Kka2,kka2_1:8,P00552,,YES,92,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.893,-3.743,2.85,,0.007,E,B,1.59,-0.19,1.719,,63.26,HHH,-0.962,0.100394,0.00307177,0.403875 kka2_1:8_L92K,kka2_1:8_92,Kka2,kka2_1:8,P00552,,YES,92,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.893,-3.743,2.85,,0.007,E,B,1.59,-0.19,1.719,,63.26,HHH,-0.962,0.100394,0.00307177,0.403875 kka2_1:8_L92N,kka2_1:8_92,Kka2,kka2_1:8,P00552,,YES,92,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.893,-4.184,3.291,,0.007,E,B,1.59,-0.19,1.719,,63.26,HHH,-0.962,0.100394,0.00307177,0.391256 kka2_1:8_L92N,kka2_1:8_92,Kka2,kka2_1:8,P00552,,YES,92,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.893,-4.184,3.291,,0.007,E,B,1.59,-0.19,1.719,,63.26,HHH,-0.962,0.100394,0.00307177,0.391256 kka2_1:8_L92S,kka2_1:8_92,Kka2,kka2_1:8,P00552,,YES,92,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.893,-3.672,2.779,,0.007,E,B,1.59,-0.19,1.719,,63.26,HHH,-0.962,0.100394,0.00307177,0.456768 kka2_1:8_L92S,kka2_1:8_92,Kka2,kka2_1:8,P00552,,YES,92,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.893,-3.672,2.779,,0.007,E,B,1.59,-0.19,1.719,,63.26,HHH,-0.962,0.100394,0.00307177,0.456768 kka2_1:8_L93C,kka2_1:8_93,Kka2,kka2_1:8,P00552,,YES,93,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.815,-4.726,3.911,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.100394,0.00131498,0.5622 kka2_1:8_L93C,kka2_1:8_93,Kka2,kka2_1:8,P00552,,YES,93,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-0.815,-4.726,3.911,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.100394,0.00131498,0.5622 kka2_1:8_L93D,kka2_1:8_93,Kka2,kka2_1:8,P00552,,YES,93,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.815,-4.139,3.324,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.100394,0.00131498,0.447201 kka2_1:8_L93D,kka2_1:8_93,Kka2,kka2_1:8,P00552,,YES,93,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-0.815,-4.139,3.324,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.100394,0.00131498,0.447201 kka2_1:8_L93E,kka2_1:8_93,Kka2,kka2_1:8,P00552,,YES,93,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.815,-3.848,3.033,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.100394,0.00131498,0.433661 kka2_1:8_L93E,kka2_1:8_93,Kka2,kka2_1:8,P00552,,YES,93,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-0.815,-3.848,3.033,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.100394,0.00131498,0.433661 kka2_1:8_L93G,kka2_1:8_93,Kka2,kka2_1:8,P00552,,YES,93,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.815,-3.804,2.989,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.100394,0.00131498,0.513284 kka2_1:8_L93G,kka2_1:8_93,Kka2,kka2_1:8,P00552,,YES,93,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-0.815,-3.804,2.989,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.100394,0.00131498,0.513284 kka2_1:8_L93K,kka2_1:8_93,Kka2,kka2_1:8,P00552,,YES,93,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.815,-3.596,2.781,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.100394,0.00131498,0.456413 kka2_1:8_L93K,kka2_1:8_93,Kka2,kka2_1:8,P00552,,YES,93,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-0.815,-3.596,2.781,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.100394,0.00131498,0.456413 kka2_1:8_L93N,kka2_1:8_93,Kka2,kka2_1:8,P00552,,YES,93,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.815,-4.082,3.267,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.100394,0.00131498,0.418188 kka2_1:8_L93N,kka2_1:8_93,Kka2,kka2_1:8,P00552,,YES,93,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-0.815,-4.082,3.267,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.100394,0.00131498,0.418188 kka2_1:8_L93S,kka2_1:8_93,Kka2,kka2_1:8,P00552,,YES,93,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.815,-3.637,2.822,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.100394,0.00131498,0.50708 kka2_1:8_L93S,kka2_1:8_93,Kka2,kka2_1:8,P00552,,YES,93,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-0.815,-3.637,2.822,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.100394,0.00131498,0.50708 kka2_1:8_L93T,kka2_1:8_93,Kka2,kka2_1:8,P00552,,YES,93,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.815,-3.473,2.658,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.100394,0.00131498,0.536099 kka2_1:8_L93T,kka2_1:8_93,Kka2,kka2_1:8,P00552,,YES,93,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-0.815,-3.473,2.658,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.100394,0.00131498,0.536099 kka2_1:8_L93W,kka2_1:8_93,Kka2,kka2_1:8,P00552,,YES,93,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.815,-5.169,4.354,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.100394,0.00131498,0.404146 kka2_1:8_L93W,kka2_1:8_93,Kka2,kka2_1:8,P00552,,YES,93,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-0.815,-5.169,4.354,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.100394,0.00131498,0.404146 kka2_1:8_L93Y,kka2_1:8_93,Kka2,kka2_1:8,P00552,,YES,93,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.815,-4.01,3.195,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.100394,0.00131498,0.435111 kka2_1:8_L93Y,kka2_1:8_93,Kka2,kka2_1:8,P00552,,YES,93,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-0.815,-4.01,3.195,,,E,B,0.55,-0.25,0.464,,19.32,HHH,-1.10867,0.100394,0.00131498,0.435111 kka2_1:8_M120C,kka2_1:8_120,Kka2,kka2_1:8,P00552,,YES,120,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-3.877,-4.689,0.812,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.100394,0.00265808,0.581086 kka2_1:8_M120C,kka2_1:8_120,Kka2,kka2_1:8,P00552,,YES,120,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-3.877,-4.689,0.812,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.100394,0.00265808,0.581086 kka2_1:8_M120D,kka2_1:8_120,Kka2,kka2_1:8,P00552,,YES,120,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-3.877,-4.17,0.293,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.100394,0.00265808,0.486112 kka2_1:8_M120D,kka2_1:8_120,Kka2,kka2_1:8,P00552,,YES,120,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-3.877,-4.17,0.293,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.100394,0.00265808,0.486112 kka2_1:8_M120E,kka2_1:8_120,Kka2,kka2_1:8,P00552,,YES,120,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-3.877,-3.916,0.039,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.100394,0.00265808,0.470964 kka2_1:8_M120E,kka2_1:8_120,Kka2,kka2_1:8,P00552,,YES,120,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-3.877,-3.916,0.039,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.100394,0.00265808,0.470964 kka2_1:8_M120F,kka2_1:8_120,Kka2,kka2_1:8,P00552,,YES,120,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-3.877,-3.689,-0.188,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.100394,0.00265808,0.489024 kka2_1:8_M120F,kka2_1:8_120,Kka2,kka2_1:8,P00552,,YES,120,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-3.877,-3.689,-0.188,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.100394,0.00265808,0.489024 kka2_1:8_M120G,kka2_1:8_120,Kka2,kka2_1:8,P00552,,YES,120,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-3.877,-3.835,-0.042,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.100394,0.00265808,0.454363 kka2_1:8_M120G,kka2_1:8_120,Kka2,kka2_1:8,P00552,,YES,120,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-3.877,-3.835,-0.042,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.100394,0.00265808,0.454363 kka2_1:8_M120H,kka2_1:8_120,Kka2,kka2_1:8,P00552,,YES,120,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-3.877,-4.957,1.08,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.100394,0.00265808,0.608875 kka2_1:8_M120H,kka2_1:8_120,Kka2,kka2_1:8,P00552,,YES,120,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-3.877,-4.957,1.08,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.100394,0.00265808,0.608875 kka2_1:8_M120N,kka2_1:8_120,Kka2,kka2_1:8,P00552,,YES,120,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-3.877,-4.174,0.297,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.100394,0.00265808,0.496119 kka2_1:8_M120N,kka2_1:8_120,Kka2,kka2_1:8,P00552,,YES,120,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-3.877,-4.174,0.297,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.100394,0.00265808,0.496119 kka2_1:8_M120P,kka2_1:8_120,Kka2,kka2_1:8,P00552,,YES,120,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-3.877,-4.131,0.254,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.100394,0.00265808,0.441694 kka2_1:8_M120P,kka2_1:8_120,Kka2,kka2_1:8,P00552,,YES,120,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-3.877,-4.131,0.254,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.100394,0.00265808,0.441694 kka2_1:8_M120Q,kka2_1:8_120,Kka2,kka2_1:8,P00552,,YES,120,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-3.877,-4.176,0.299,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.100394,0.00265808,0.508639 kka2_1:8_M120Q,kka2_1:8_120,Kka2,kka2_1:8,P00552,,YES,120,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-3.877,-4.176,0.299,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.100394,0.00265808,0.508639 kka2_1:8_M120R,kka2_1:8_120,Kka2,kka2_1:8,P00552,,YES,120,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-3.877,-4.005,0.128,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.100394,0.00265808,0.497698 kka2_1:8_M120R,kka2_1:8_120,Kka2,kka2_1:8,P00552,,YES,120,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-3.877,-4.005,0.128,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.100394,0.00265808,0.497698 kka2_1:8_M120Y,kka2_1:8_120,Kka2,kka2_1:8,P00552,,YES,120,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-3.877,-3.989,0.112,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.100394,0.00265808,0.490581 kka2_1:8_M120Y,kka2_1:8_120,Kka2,kka2_1:8,P00552,,YES,120,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-3.877,-3.989,0.112,,,H,A,1.59,-0.42,2.259,,92.05,HHB,-2.16733,0.100394,0.00265808,0.490581 kka2_1:8_M148C,kka2_1:8_148,Kka2,kka2_1:8,P00552,,YES,148,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.847,-4.865,3.018,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.100394,0.00982664,0.574222 kka2_1:8_M148C,kka2_1:8_148,Kka2,kka2_1:8,P00552,,YES,148,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.847,-4.865,3.018,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.100394,0.00982664,0.574222 kka2_1:8_M148E,kka2_1:8_148,Kka2,kka2_1:8,P00552,,YES,148,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.847,-3.876,2.029,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.100394,0.00982664,0.448068 kka2_1:8_M148E,kka2_1:8_148,Kka2,kka2_1:8,P00552,,YES,148,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.847,-3.876,2.029,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.100394,0.00982664,0.448068 kka2_1:8_M148G,kka2_1:8_148,Kka2,kka2_1:8,P00552,,YES,148,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.847,-3.731,1.884,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.100394,0.00982664,0.450071 kka2_1:8_M148G,kka2_1:8_148,Kka2,kka2_1:8,P00552,,YES,148,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.847,-3.731,1.884,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.100394,0.00982664,0.450071 kka2_1:8_M148H,kka2_1:8_148,Kka2,kka2_1:8,P00552,,YES,148,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.847,-4.993,3.146,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.100394,0.00982664,0.496688 kka2_1:8_M148H,kka2_1:8_148,Kka2,kka2_1:8,P00552,,YES,148,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.847,-4.993,3.146,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.100394,0.00982664,0.496688 kka2_1:8_M148R,kka2_1:8_148,Kka2,kka2_1:8,P00552,,YES,148,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.847,-3.206,1.359,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.100394,0.00982664,0.513118 kka2_1:8_M148R,kka2_1:8_148,Kka2,kka2_1:8,P00552,,YES,148,M,R,MR,Hydrophobic,PositiveCharge,5.74,6.34148,0.601478,91,149,174,25,162.9,173.4,10.5,-1.847,-3.206,1.359,,0.268,H,A,0.55,0.71,1.508,,64.39,BHA,-1.65467,0.100394,0.00982664,0.513118 kka2_1:8_M178K,kka2_1:8_178,Kka2,kka2_1:8,P00552,,YES,178,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-3.206,-2.451,-0.755,,0.554,,b,1.59,0.68,13.268,13.268,71.59,BHO,-2.154,0.100394,0.00717253,0.916205 kka2_1:8_M178K,kka2_1:8_178,Kka2,kka2_1:8,P00552,,YES,178,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-3.206,-2.451,-0.755,,0.554,,b,1.59,0.68,13.268,13.268,71.59,BHO,-2.154,0.100394,0.00717253,0.916205 kka2_1:8_M178N,kka2_1:8_178,Kka2,kka2_1:8,P00552,,YES,178,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-3.206,-3.899,0.693,,0.554,,b,1.59,0.68,13.268,13.268,71.59,BHO,-2.154,0.100394,0.00717253,0.738999 kka2_1:8_M178N,kka2_1:8_178,Kka2,kka2_1:8,P00552,,YES,178,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-3.206,-3.899,0.693,,0.554,,b,1.59,0.68,13.268,13.268,71.59,BHO,-2.154,0.100394,0.00717253,0.738999 kka2_1:8_M178P,kka2_1:8_178,Kka2,kka2_1:8,P00552,,YES,178,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-3.206,-3.217,0.011,,0.554,,b,1.59,0.68,13.268,13.268,71.59,BHO,-2.154,0.100394,0.00717253,0.752634 kka2_1:8_M178P,kka2_1:8_178,Kka2,kka2_1:8,P00552,,YES,178,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-3.206,-3.217,0.011,,0.554,,b,1.59,0.68,13.268,13.268,71.59,BHO,-2.154,0.100394,0.00717253,0.752634 kka2_1:8_M1A,kka2_1:8_1,Kka2,kka2_1:8,P00552,,YES,1,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.787,-2.808,1.021,,,,,,,16.725,16.725,62.12,NAHH,-1.787,0.100394,0.00251939,0.84165 kka2_1:8_M1A,kka2_1:8_1,Kka2,kka2_1:8,P00552,,YES,1,M,A,MA,Hydrophobic,Hydrophobic,5.74,6,0.26,84,149,89,-60,162.9,88.6,-74.3,-1.787,-2.808,1.021,,,,,,,16.725,16.725,62.12,NAHH,-1.787,0.100394,0.00251939,0.84165 kka2_1:8_M1C,kka2_1:8_1,Kka2,kka2_1:8,P00552,,YES,1,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.787,-4.448,2.661,,,,,,,16.725,16.725,62.12,NAHH,-1.787,0.100394,0.00251939,0.889638 kka2_1:8_M1C,kka2_1:8_1,Kka2,kka2_1:8,P00552,,YES,1,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.787,-4.448,2.661,,,,,,,16.725,16.725,62.12,NAHH,-1.787,0.100394,0.00251939,0.889638 kka2_1:8_M1D,kka2_1:8_1,Kka2,kka2_1:8,P00552,,YES,1,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.787,-3.73,1.943,,,,,,,16.725,16.725,62.12,NAHH,-1.787,0.100394,0.00251939,0.860498 kka2_1:8_M1D,kka2_1:8_1,Kka2,kka2_1:8,P00552,,YES,1,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.787,-3.73,1.943,,,,,,,16.725,16.725,62.12,NAHH,-1.787,0.100394,0.00251939,0.860498 kka2_1:8_M1E,kka2_1:8_1,Kka2,kka2_1:8,P00552,,YES,1,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.787,-3.476,1.689,,,,,,,16.725,16.725,62.12,NAHH,-1.787,0.100394,0.00251939,0.816488 kka2_1:8_M1E,kka2_1:8_1,Kka2,kka2_1:8,P00552,,YES,1,M,E,ME,Hydrophobic,negativeCharge,5.74,3.22,-2.52,126,149,147,-2,162.9,138.4,-24.5,-1.787,-3.476,1.689,,,,,,,16.725,16.725,62.12,NAHH,-1.787,0.100394,0.00251939,0.816488 kka2_1:8_M1F,kka2_1:8_1,Kka2,kka2_1:8,P00552,,YES,1,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.787,-3.498,1.711,,,,,,,16.725,16.725,62.12,NAHH,-1.787,0.100394,0.00251939,0.817197 kka2_1:8_M1F,kka2_1:8_1,Kka2,kka2_1:8,P00552,,YES,1,M,F,MF,Hydrophobic,Hydrophobic,5.74,3.32051,-2.41949,28,149,165,16,162.9,189.9,27,-1.787,-3.498,1.711,,,,,,,16.725,16.725,62.12,NAHH,-1.787,0.100394,0.00251939,0.817197 kka2_1:8_M1G,kka2_1:8_1,Kka2,kka2_1:8,P00552,,YES,1,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.787,-3.394,1.607,,,,,,,16.725,16.725,62.12,NAHH,-1.787,0.100394,0.00251939,0.802806 kka2_1:8_M1G,kka2_1:8_1,Kka2,kka2_1:8,P00552,,YES,1,M,G,MG,Hydrophobic,Special,5.74,3.29388,-2.44612,127,149,75,-74,162.9,60.1,-102.8,-1.787,-3.394,1.607,,,,,,,16.725,16.725,62.12,NAHH,-1.787,0.100394,0.00251939,0.802806 kka2_1:8_M1H,kka2_1:8_1,Kka2,kka2_1:8,P00552,,YES,1,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.787,-4.561,2.774,,,,,,,16.725,16.725,62.12,NAHH,-1.787,0.100394,0.00251939,0.872023 kka2_1:8_M1H,kka2_1:8_1,Kka2,kka2_1:8,P00552,,YES,1,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.787,-4.561,2.774,,,,,,,16.725,16.725,62.12,NAHH,-1.787,0.100394,0.00251939,0.872023 kka2_1:8_M1K,kka2_1:8_1,Kka2,kka2_1:8,P00552,,YES,1,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.787,-3.337,1.55,,,,,,,16.725,16.725,62.12,NAHH,-1.787,0.100394,0.00251939,0.813348 kka2_1:8_M1K,kka2_1:8_1,Kka2,kka2_1:8,P00552,,YES,1,M,K,MK,Hydrophobic,PositiveCharge,5.74,9.74,4,95,149,146,-3,162.9,168.6,5.7,-1.787,-3.337,1.55,,,,,,,16.725,16.725,62.12,NAHH,-1.787,0.100394,0.00251939,0.813348 kka2_1:8_M1N,kka2_1:8_1,Kka2,kka2_1:8,P00552,,YES,1,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.787,-3.778,1.991,,,,,,,16.725,16.725,62.12,NAHH,-1.787,0.100394,0.00251939,0.874449 kka2_1:8_M1N,kka2_1:8_1,Kka2,kka2_1:8,P00552,,YES,1,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.787,-3.778,1.991,,,,,,,16.725,16.725,62.12,NAHH,-1.787,0.100394,0.00251939,0.874449 kka2_1:8_M1P,kka2_1:8_1,Kka2,kka2_1:8,P00552,,YES,1,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.787,-3.691,1.904,,,,,,,16.725,16.725,62.12,NAHH,-1.787,0.100394,0.00251939,0.832738 kka2_1:8_M1P,kka2_1:8_1,Kka2,kka2_1:8,P00552,,YES,1,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.787,-3.691,1.904,,,,,,,16.725,16.725,62.12,NAHH,-1.787,0.100394,0.00251939,0.832738 kka2_1:8_M1Q,kka2_1:8_1,Kka2,kka2_1:8,P00552,,YES,1,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.787,-3.614,1.827,,,,,,,16.725,16.725,62.12,NAHH,-1.787,0.100394,0.00251939,0.831161 kka2_1:8_M1Q,kka2_1:8_1,Kka2,kka2_1:8,P00552,,YES,1,M,Q,MQ,Hydrophobic,Polar,5.74,6.24429,0.504286,101,149,146,-3,162.9,143.8,-19.1,-1.787,-3.614,1.827,,,,,,,16.725,16.725,62.12,NAHH,-1.787,0.100394,0.00251939,0.831161 kka2_1:8_M1S,kka2_1:8_1,Kka2,kka2_1:8,P00552,,YES,1,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.787,-3.266,1.479,,,,,,,16.725,16.725,62.12,NAHH,-1.787,0.100394,0.00251939,0.786738 kka2_1:8_M1S,kka2_1:8_1,Kka2,kka2_1:8,P00552,,YES,1,M,S,MS,Hydrophobic,Polar,5.74,5.68,-0.06,135,149,105,-44,162.9,89,-73.9,-1.787,-3.266,1.479,,,,,,,16.725,16.725,62.12,NAHH,-1.787,0.100394,0.00251939,0.786738 kka2_1:8_M1W,kka2_1:8_1,Kka2,kka2_1:8,P00552,,YES,1,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.787,-4.812,3.025,,,,,,,16.725,16.725,62.12,NAHH,-1.787,0.100394,0.00251939,0.868213 kka2_1:8_M1W,kka2_1:8_1,Kka2,kka2_1:8,P00552,,YES,1,M,W,MW,Hydrophobic,Hydrophobic,5.74,5.89,0.15,67,149,204,55,162.9,227.8,64.9,-1.787,-4.812,3.025,,,,,,,16.725,16.725,62.12,NAHH,-1.787,0.100394,0.00251939,0.868213 kka2_1:8_M1Y,kka2_1:8_1,Kka2,kka2_1:8,P00552,,YES,1,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.787,-3.748,1.961,,,,,,,16.725,16.725,62.12,NAHH,-1.787,0.100394,0.00251939,0.867186 kka2_1:8_M1Y,kka2_1:8_1,Kka2,kka2_1:8,P00552,,YES,1,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.787,-3.748,1.961,,,,,,,16.725,16.725,62.12,NAHH,-1.787,0.100394,0.00251939,0.867186 kka2_1:8_N58A,kka2_1:8_58,Kka2,kka2_1:8,P00552,,YES,58,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-2.641,-1.819,-0.822,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.100394,0.00793425,0.80356 kka2_1:8_N58A,kka2_1:8_58,Kka2,kka2_1:8,P00552,,YES,58,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-2.641,-1.819,-0.822,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.100394,0.00793425,0.80356 kka2_1:8_N58F,kka2_1:8_58,Kka2,kka2_1:8,P00552,,YES,58,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-2.641,-4.413,1.772,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.100394,0.00793425,0.555854 kka2_1:8_N58F,kka2_1:8_58,Kka2,kka2_1:8,P00552,,YES,58,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-2.641,-4.413,1.772,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.100394,0.00793425,0.555854 kka2_1:8_N58G,kka2_1:8_58,Kka2,kka2_1:8,P00552,,YES,58,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-2.641,-1.779,-0.862,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.100394,0.00793425,0.789586 kka2_1:8_N58G,kka2_1:8_58,Kka2,kka2_1:8,P00552,,YES,58,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-2.641,-1.779,-0.862,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.100394,0.00793425,0.789586 kka2_1:8_N58H,kka2_1:8_58,Kka2,kka2_1:8,P00552,,YES,58,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-2.641,-4.779,2.138,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.100394,0.00793425,0.677682 kka2_1:8_N58H,kka2_1:8_58,Kka2,kka2_1:8,P00552,,YES,58,N,H,NH,Polar,PositiveCharge,5.47157,7.59,2.11843,68,132,155,23,114.1,153.2,39.1,-2.641,-4.779,2.138,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.100394,0.00793425,0.677682 kka2_1:8_N58I,kka2_1:8_58,Kka2,kka2_1:8,P00552,,YES,58,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-2.641,-4.075,1.434,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.100394,0.00793425,0.55171 kka2_1:8_N58I,kka2_1:8_58,Kka2,kka2_1:8,P00552,,YES,58,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-2.641,-4.075,1.434,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.100394,0.00793425,0.55171 kka2_1:8_N58L,kka2_1:8_58,Kka2,kka2_1:8,P00552,,YES,58,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-2.641,-3.653,1.012,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.100394,0.00793425,0.538325 kka2_1:8_N58L,kka2_1:8_58,Kka2,kka2_1:8,P00552,,YES,58,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-2.641,-3.653,1.012,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.100394,0.00793425,0.538325 kka2_1:8_N58M,kka2_1:8_58,Kka2,kka2_1:8,P00552,,YES,58,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-2.641,-4.871,2.23,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.100394,0.00793425,0.673184 kka2_1:8_N58M,kka2_1:8_58,Kka2,kka2_1:8,P00552,,YES,58,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-2.641,-4.871,2.23,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.100394,0.00793425,0.673184 kka2_1:8_N58P,kka2_1:8_58,Kka2,kka2_1:8,P00552,,YES,58,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-2.641,-4.016,1.375,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.100394,0.00793425,0.474392 kka2_1:8_N58P,kka2_1:8_58,Kka2,kka2_1:8,P00552,,YES,58,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-2.641,-4.016,1.375,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.100394,0.00793425,0.474392 kka2_1:8_N58Q,kka2_1:8_58,Kka2,kka2_1:8,P00552,,YES,58,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-2.641,-4.107,1.466,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.100394,0.00793425,0.57622 kka2_1:8_N58Q,kka2_1:8_58,Kka2,kka2_1:8,P00552,,YES,58,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-2.641,-4.107,1.466,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.100394,0.00793425,0.57622 kka2_1:8_N58R,kka2_1:8_58,Kka2,kka2_1:8,P00552,,YES,58,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-2.641,-3.198,0.557,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.100394,0.00793425,0.63921 kka2_1:8_N58R,kka2_1:8_58,Kka2,kka2_1:8,P00552,,YES,58,N,R,NR,Polar,PositiveCharge,5.47157,6.34148,0.869903,86,132,174,42,114.1,173.4,59.3,-2.641,-3.198,0.557,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.100394,0.00793425,0.63921 kka2_1:8_N58V,kka2_1:8_58,Kka2,kka2_1:8,P00552,,YES,58,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-2.641,-3.703,1.062,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.100394,0.00793425,0.540563 kka2_1:8_N58V,kka2_1:8_58,Kka2,kka2_1:8,P00552,,YES,58,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-2.641,-3.703,1.062,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.100394,0.00793425,0.540563 kka2_1:8_N58W,kka2_1:8_58,Kka2,kka2_1:8,P00552,,YES,58,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-2.641,-5.525,2.884,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.100394,0.00793425,0.696479 kka2_1:8_N58W,kka2_1:8_58,Kka2,kka2_1:8,P00552,,YES,58,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-2.641,-5.525,2.884,,0.131,S,A,0.43,0.72,1.288,,71.59,HPA,-1.83033,0.100394,0.00793425,0.696479 kka2_1:8_P109E,kka2_1:8_109,Kka2,kka2_1:8,P00552,,YES,109,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.412,-2.892,1.48,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.100394,0.0070929,0.499472 kka2_1:8_P109E,kka2_1:8_109,Kka2,kka2_1:8,P00552,,YES,109,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.412,-2.892,1.48,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.100394,0.0070929,0.499472 kka2_1:8_P109G,kka2_1:8_109,Kka2,kka2_1:8,P00552,,YES,109,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.412,-3.439,2.027,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.100394,0.0070929,0.518799 kka2_1:8_P109G,kka2_1:8_109,Kka2,kka2_1:8,P00552,,YES,109,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.412,-3.439,2.027,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.100394,0.0070929,0.518799 kka2_1:8_P109W,kka2_1:8_109,Kka2,kka2_1:8,P00552,,YES,109,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.412,-3.457,2.045,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.100394,0.0070929,0.49252 kka2_1:8_P109W,kka2_1:8_109,Kka2,kka2_1:8,P00552,,YES,109,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.412,-3.457,2.045,,0.376,H,A,0.52,-1.25,7.463,,65.53,HOH,-1.84567,0.100394,0.0070929,0.49252 kka2_1:8_P128D,kka2_1:8_128,Kka2,kka2_1:8,P00552,,YES,128,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.922,-4.006,2.084,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.100394,0.00774689,0.41293 kka2_1:8_P128D,kka2_1:8_128,Kka2,kka2_1:8,P00552,,YES,128,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.922,-4.006,2.084,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.100394,0.00774689,0.41293 kka2_1:8_P128G,kka2_1:8_128,Kka2,kka2_1:8,P00552,,YES,128,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.922,-3.745,1.823,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.100394,0.00774689,0.420782 kka2_1:8_P128G,kka2_1:8_128,Kka2,kka2_1:8,P00552,,YES,128,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.922,-3.745,1.823,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.100394,0.00774689,0.420782 kka2_1:8_P128K,kka2_1:8_128,Kka2,kka2_1:8,P00552,,YES,128,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.922,-3.891,1.969,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.100394,0.00774689,0.417843 kka2_1:8_P128K,kka2_1:8_128,Kka2,kka2_1:8,P00552,,YES,128,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.922,-3.891,1.969,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.100394,0.00774689,0.417843 kka2_1:8_P128N,kka2_1:8_128,Kka2,kka2_1:8,P00552,,YES,128,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.922,-4.215,2.293,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.100394,0.00774689,0.45231 kka2_1:8_P128N,kka2_1:8_128,Kka2,kka2_1:8,P00552,,YES,128,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.922,-4.215,2.293,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.100394,0.00774689,0.45231 kka2_1:8_P128Y,kka2_1:8_128,Kka2,kka2_1:8,P00552,,YES,128,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.922,-3.242,1.32,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.100394,0.00774689,0.48596 kka2_1:8_P128Y,kka2_1:8_128,Kka2,kka2_1:8,P00552,,YES,128,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.922,-3.242,1.32,,0.316,G,A,0.52,0.4,2.257,,56.06,AOH,-1.64733,0.100394,0.00774689,0.48596 kka2_1:8_P12N,kka2_1:8_12,Kka2,kka2_1:8,P00552,,YES,12,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.853,-3.936,3.083,,,.,B,0.52,1.25,2.41,,48.11,POH,-1.80767,0.100394,0.00500011,0.485421 kka2_1:8_P12N,kka2_1:8_12,Kka2,kka2_1:8,P00552,,YES,12,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.853,-3.936,3.083,,,.,B,0.52,1.25,2.41,,48.11,POH,-1.80767,0.100394,0.00500011,0.485421 kka2_1:8_P132C,kka2_1:8_132,Kka2,kka2_1:8,P00552,,YES,132,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.775,-5.083,4.308,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.100394,0.0018489,0.552508 kka2_1:8_P132C,kka2_1:8_132,Kka2,kka2_1:8,P00552,,YES,132,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-0.775,-5.083,4.308,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.100394,0.0018489,0.552508 kka2_1:8_P132E,kka2_1:8_132,Kka2,kka2_1:8,P00552,,YES,132,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.775,-3.466,2.691,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.100394,0.0018489,0.45921 kka2_1:8_P132E,kka2_1:8_132,Kka2,kka2_1:8,P00552,,YES,132,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-0.775,-3.466,2.691,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.100394,0.0018489,0.45921 kka2_1:8_P132F,kka2_1:8_132,Kka2,kka2_1:8,P00552,,YES,132,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.775,-4.513,3.738,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.100394,0.0018489,0.487946 kka2_1:8_P132F,kka2_1:8_132,Kka2,kka2_1:8,P00552,,YES,132,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-0.775,-4.513,3.738,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.100394,0.0018489,0.487946 kka2_1:8_P132N,kka2_1:8_132,Kka2,kka2_1:8,P00552,,YES,132,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.775,-3.857,3.082,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.100394,0.0018489,0.492266 kka2_1:8_P132N,kka2_1:8_132,Kka2,kka2_1:8,P00552,,YES,132,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-0.775,-3.857,3.082,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.100394,0.0018489,0.492266 kka2_1:8_P132Y,kka2_1:8_132,Kka2,kka2_1:8,P00552,,YES,132,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.775,-4.414,3.639,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.100394,0.0018489,0.480126 kka2_1:8_P132Y,kka2_1:8_132,Kka2,kka2_1:8,P00552,,YES,132,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-0.775,-4.414,3.639,,0.692,.,A,0.52,0.56,2.19,,44.7,OOH,-0.825667,0.100394,0.0018489,0.480126 kka2_1:8_P167C,kka2_1:8_167,Kka2,kka2_1:8,P00552,,YES,167,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-2.403,-4.818,2.415,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.100394,0.00543203,0.703208 kka2_1:8_P167C,kka2_1:8_167,Kka2,kka2_1:8,P00552,,YES,167,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-2.403,-4.818,2.415,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.100394,0.00543203,0.703208 kka2_1:8_P167F,kka2_1:8_167,Kka2,kka2_1:8,P00552,,YES,167,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-2.403,-4.229,1.826,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.100394,0.00543203,0.58253 kka2_1:8_P167F,kka2_1:8_167,Kka2,kka2_1:8,P00552,,YES,167,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-2.403,-4.229,1.826,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.100394,0.00543203,0.58253 kka2_1:8_P167Y,kka2_1:8_167,Kka2,kka2_1:8,P00552,,YES,167,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-2.403,-4.35,1.947,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.100394,0.00543203,0.607749 kka2_1:8_P167Y,kka2_1:8_167,Kka2,kka2_1:8,P00552,,YES,167,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-2.403,-4.35,1.947,,0.18,H,A,0.52,0.75,4.757,,64.39,HOH,-2.26633,0.100394,0.00543203,0.607749 kka2_1:8_P249C,kka2_1:8_249,Kka2,kka2_1:8,P00552,,YES,249,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.867,-5.002,3.135,,0.406,.,B,0.52,-0.01,1.699,,92.05,HOA,-1.66867,0.100394,0.011045,0.792818 kka2_1:8_P249C,kka2_1:8_249,Kka2,kka2_1:8,P00552,,YES,249,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.867,-5.002,3.135,,0.406,.,B,0.52,-0.01,1.699,,92.05,HOA,-1.66867,0.100394,0.011045,0.792818 kka2_1:8_P249D,kka2_1:8_249,Kka2,kka2_1:8,P00552,,YES,249,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.867,-3.169,1.302,,0.406,.,B,0.52,-0.01,1.699,,92.05,HOA,-1.66867,0.100394,0.011045,0.664735 kka2_1:8_P249D,kka2_1:8_249,Kka2,kka2_1:8,P00552,,YES,249,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.867,-3.169,1.302,,0.406,.,B,0.52,-0.01,1.699,,92.05,HOA,-1.66867,0.100394,0.011045,0.664735 kka2_1:8_P249G,kka2_1:8_249,Kka2,kka2_1:8,P00552,,YES,249,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.867,-3.661,1.794,,0.406,.,B,0.52,-0.01,1.699,,92.05,HOA,-1.66867,0.100394,0.011045,0.690979 kka2_1:8_P249G,kka2_1:8_249,Kka2,kka2_1:8,P00552,,YES,249,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.867,-3.661,1.794,,0.406,.,B,0.52,-0.01,1.699,,92.05,HOA,-1.66867,0.100394,0.011045,0.690979 kka2_1:8_P249N,kka2_1:8_249,Kka2,kka2_1:8,P00552,,YES,249,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.867,-4.142,2.275,,0.406,.,B,0.52,-0.01,1.699,,92.05,HOA,-1.66867,0.100394,0.011045,0.772631 kka2_1:8_P249N,kka2_1:8_249,Kka2,kka2_1:8,P00552,,YES,249,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.867,-4.142,2.275,,0.406,.,B,0.52,-0.01,1.699,,92.05,HOA,-1.66867,0.100394,0.011045,0.772631 kka2_1:8_P249Y,kka2_1:8_249,Kka2,kka2_1:8,P00552,,YES,249,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.867,-4.279,2.412,,0.406,.,B,0.52,-0.01,1.699,,92.05,HOA,-1.66867,0.100394,0.011045,0.774705 kka2_1:8_P249Y,kka2_1:8_249,Kka2,kka2_1:8,P00552,,YES,249,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.867,-4.279,2.412,,0.406,.,B,0.52,-0.01,1.699,,92.05,HOA,-1.66867,0.100394,0.011045,0.774705 kka2_1:8_P98I,kka2_1:8_98,Kka2,kka2_1:8,P00552,,YES,98,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.526,-4.079,2.553,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.100394,0.00622754,0.45652 kka2_1:8_P98I,kka2_1:8_98,Kka2,kka2_1:8,P00552,,YES,98,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.526,-4.079,2.553,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.100394,0.00622754,0.45652 kka2_1:8_P98W,kka2_1:8_98,Kka2,kka2_1:8,P00552,,YES,98,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.526,-5.629,4.103,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.100394,0.00622754,0.489058 kka2_1:8_P98W,kka2_1:8_98,Kka2,kka2_1:8,P00552,,YES,98,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.526,-5.629,4.103,,0.391,S,B,0.52,-0.65,1.151,,63.26,HOO,-1.19167,0.100394,0.00622754,0.489058 kka2_1:8_Q100F,kka2_1:8_100,Kka2,kka2_1:8,P00552,,YES,100,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.77,-4.378,1.608,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.100394,0.0066405,0.646986 kka2_1:8_Q100F,kka2_1:8_100,Kka2,kka2_1:8,P00552,,YES,100,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.77,-4.378,1.608,,0.646,E,B,0.64,-0.79,0.416,,71.59,OPA,-1.46467,0.100394,0.0066405,0.646986 kka2_1:8_Q155C,kka2_1:8_155,Kka2,kka2_1:8,P00552,,YES,155,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.606,-5.171,2.565,,0.525,T,A,0.64,1.49,,,63.64,APA,-1.726,0.100394,0.00641853,0.871163 kka2_1:8_Q155C,kka2_1:8_155,Kka2,kka2_1:8,P00552,,YES,155,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-2.606,-5.171,2.565,,0.525,T,A,0.64,1.49,,,63.64,APA,-1.726,0.100394,0.00641853,0.871163 kka2_1:8_Q155I,kka2_1:8_155,Kka2,kka2_1:8,P00552,,YES,155,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.606,-3.926,1.32,,0.525,T,A,0.64,1.49,,,63.64,APA,-1.726,0.100394,0.00641853,0.769816 kka2_1:8_Q155I,kka2_1:8_155,Kka2,kka2_1:8,P00552,,YES,155,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.606,-3.926,1.32,,0.525,T,A,0.64,1.49,,,63.64,APA,-1.726,0.100394,0.00641853,0.769816 kka2_1:8_Q155T,kka2_1:8_155,Kka2,kka2_1:8,P00552,,YES,155,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.606,-3.529,0.923,,0.525,T,A,0.64,1.49,,,63.64,APA,-1.726,0.100394,0.00641853,0.860983 kka2_1:8_Q155T,kka2_1:8_155,Kka2,kka2_1:8,P00552,,YES,155,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.606,-3.529,0.923,,0.525,T,A,0.64,1.49,,,63.64,APA,-1.726,0.100394,0.00641853,0.860983 kka2_1:8_Q163S,kka2_1:8_163,Kka2,kka2_1:8,P00552,,YES,163,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.162,-3.535,1.373,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.100394,0.00719507,0.760358 kka2_1:8_Q163S,kka2_1:8_163,Kka2,kka2_1:8,P00552,,YES,163,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.162,-3.535,1.373,,0.58,T,B,0.64,1.85,1.679,,64.02,BPO,-1.78333,0.100394,0.00719507,0.760358 kka2_1:8_Q252I,kka2_1:8_252,Kka2,kka2_1:8,P00552,,YES,252,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.63,-4.083,1.453,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.100394,0.0121001,0.851849 kka2_1:8_Q252I,kka2_1:8_252,Kka2,kka2_1:8,P00552,,YES,252,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.63,-4.083,1.453,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.100394,0.0121001,0.851849 kka2_1:8_Q252S,kka2_1:8_252,Kka2,kka2_1:8,P00552,,YES,252,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.63,-2.755,0.125,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.100394,0.0121001,0.922954 kka2_1:8_Q252S,kka2_1:8_252,Kka2,kka2_1:8,P00552,,YES,252,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.63,-2.755,0.125,,0.906,H,A,0.64,0.35,,,92.05,PPB,-2.20733,0.100394,0.0121001,0.922954 kka2_1:8_Q26I,kka2_1:8_26,Kka2,kka2_1:8,P00552,,YES,26,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.18,-4.055,1.875,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.100394,0.00708962,0.701463 kka2_1:8_Q26I,kka2_1:8_26,Kka2,kka2_1:8,P00552,,YES,26,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.18,-4.055,1.875,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.100394,0.00708962,0.701463 kka2_1:8_Q26S,kka2_1:8_26,Kka2,kka2_1:8,P00552,,YES,26,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.18,-3.511,1.331,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.100394,0.00708962,0.713346 kka2_1:8_Q26S,kka2_1:8_26,Kka2,kka2_1:8,P00552,,YES,26,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-2.18,-3.511,1.331,,0.448,E,B,0.64,0.44,1.185,,92.05,HPP,-2.11167,0.100394,0.00708962,0.713346 kka2_1:8_Q27C,kka2_1:8_27,Kka2,kka2_1:8,P00552,,YES,27,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-1.659,-5.15,3.491,,0.608,.,A,0.64,0.71,3.919,,65.53,PPP,-1.90733,0.100394,0.00595365,0.67273 kka2_1:8_Q27C,kka2_1:8_27,Kka2,kka2_1:8,P00552,,YES,27,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-1.659,-5.15,3.491,,0.608,.,A,0.64,0.71,3.919,,65.53,PPP,-1.90733,0.100394,0.00595365,0.67273 kka2_1:8_Q27G,kka2_1:8_27,Kka2,kka2_1:8,P00552,,YES,27,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-1.659,-3.564,1.905,,0.608,.,A,0.64,0.71,3.919,,65.53,PPP,-1.90733,0.100394,0.00595365,0.653952 kka2_1:8_Q27G,kka2_1:8_27,Kka2,kka2_1:8,P00552,,YES,27,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-1.659,-3.564,1.905,,0.608,.,A,0.64,0.71,3.919,,65.53,PPP,-1.90733,0.100394,0.00595365,0.653952 kka2_1:8_Q27V,kka2_1:8_27,Kka2,kka2_1:8,P00552,,YES,27,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-1.659,-2.648,0.989,,0.608,.,A,0.64,0.71,3.919,,65.53,PPP,-1.90733,0.100394,0.00595365,0.676808 kka2_1:8_Q27V,kka2_1:8_27,Kka2,kka2_1:8,P00552,,YES,27,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-1.659,-2.648,0.989,,0.608,.,A,0.64,0.71,3.919,,65.53,PPP,-1.90733,0.100394,0.00595365,0.676808 kka2_1:8_Q42A,kka2_1:8_42,Kka2,kka2_1:8,P00552,,YES,42,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.907,-2.221,-0.686,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.100394,0.00679212,1.03517 kka2_1:8_Q42A,kka2_1:8_42,Kka2,kka2_1:8,P00552,,YES,42,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-2.907,-2.221,-0.686,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.100394,0.00679212,1.03517 kka2_1:8_Q42D,kka2_1:8_42,Kka2,kka2_1:8,P00552,,YES,42,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.907,-2.294,-0.613,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.100394,0.00679212,1.02559 kka2_1:8_Q42D,kka2_1:8_42,Kka2,kka2_1:8,P00552,,YES,42,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-2.907,-2.294,-0.613,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.100394,0.00679212,1.02559 kka2_1:8_Q42F,kka2_1:8_42,Kka2,kka2_1:8,P00552,,YES,42,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.907,-4.511,1.604,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.100394,0.00679212,0.789889 kka2_1:8_Q42F,kka2_1:8_42,Kka2,kka2_1:8,P00552,,YES,42,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.907,-4.511,1.604,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.100394,0.00679212,0.789889 kka2_1:8_Q42V,kka2_1:8_42,Kka2,kka2_1:8,P00552,,YES,42,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.907,-3.778,0.871,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.100394,0.00679212,0.798261 kka2_1:8_Q42V,kka2_1:8_42,Kka2,kka2_1:8,P00552,,YES,42,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.907,-3.778,0.871,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.100394,0.00679212,0.798261 kka2_1:8_Q42W,kka2_1:8_42,Kka2,kka2_1:8,P00552,,YES,42,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.907,-5.634,2.727,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.100394,0.00679212,0.762662 kka2_1:8_Q42W,kka2_1:8_42,Kka2,kka2_1:8,P00552,,YES,42,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.907,-5.634,2.727,,1.044,T,B,0.64,-0.8,,,71.59,HPO,-2.12433,0.100394,0.00679212,0.762662 kka2_1:8_Q4G,kka2_1:8_4,Kka2,kka2_1:8,P00552,,YES,4,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.361,-1.897,-0.464,,,,,,,2.026,,71.59,APA,-1.95533,0.100394,0.00239179,1.04049 kka2_1:8_Q4G,kka2_1:8_4,Kka2,kka2_1:8,P00552,,YES,4,Q,G,QG,Polar,Special,6.24429,3.29388,-2.95041,87,146,75,-71,143.8,60.1,-83.7,-2.361,-1.897,-0.464,,,,,,,2.026,,71.59,APA,-1.95533,0.100394,0.00239179,1.04049 kka2_1:8_Q61I,kka2_1:8_61,Kka2,kka2_1:8,P00552,,YES,61,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.982,-3.937,0.955,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.100394,0.00612092,0.753127 kka2_1:8_Q61I,kka2_1:8_61,Kka2,kka2_1:8,P00552,,YES,61,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-2.982,-3.937,0.955,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.100394,0.00612092,0.753127 kka2_1:8_Q61M,kka2_1:8_61,Kka2,kka2_1:8,P00552,,YES,61,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.982,-4.764,1.782,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.100394,0.00612092,0.773255 kka2_1:8_Q61M,kka2_1:8_61,Kka2,kka2_1:8,P00552,,YES,61,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.982,-4.764,1.782,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.100394,0.00612092,0.773255 kka2_1:8_Q61N,kka2_1:8_61,Kka2,kka2_1:8,P00552,,YES,61,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.982,-3.133,0.151,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.100394,0.00612092,0.848484 kka2_1:8_Q61N,kka2_1:8_61,Kka2,kka2_1:8,P00552,,YES,61,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-2.982,-3.133,0.151,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.100394,0.00612092,0.848484 kka2_1:8_Q61T,kka2_1:8_61,Kka2,kka2_1:8,P00552,,YES,61,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.982,-2.975,-0.007,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.100394,0.00612092,0.851762 kka2_1:8_Q61T,kka2_1:8_61,Kka2,kka2_1:8,P00552,,YES,61,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-2.982,-2.975,-0.007,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.100394,0.00612092,0.851762 kka2_1:8_Q61V,kka2_1:8_61,Kka2,kka2_1:8,P00552,,YES,61,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.982,-2.81,-0.172,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.100394,0.00612092,0.882333 kka2_1:8_Q61V,kka2_1:8_61,Kka2,kka2_1:8,P00552,,YES,61,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-2.982,-2.81,-0.172,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.100394,0.00612092,0.882333 kka2_1:8_Q61Y,kka2_1:8_61,Kka2,kka2_1:8,P00552,,YES,61,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.982,-4.455,1.473,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.100394,0.00612092,0.771068 kka2_1:8_Q61Y,kka2_1:8_61,Kka2,kka2_1:8,P00552,,YES,61,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-2.982,-4.455,1.473,,0.591,H,A,0.64,0.41,25.686,25.686,65.53,HPA,-1.85667,0.100394,0.00612092,0.771068 kka2_1:8_R121A,kka2_1:8_121,Kka2,kka2_1:8,P00552,,YES,121,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.552,-2.713,1.161,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.100394,0.00523326,0.636479 kka2_1:8_R121A,kka2_1:8_121,Kka2,kka2_1:8,P00552,,YES,121,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.552,-2.713,1.161,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.100394,0.00523326,0.636479 kka2_1:8_R121E,kka2_1:8_121,Kka2,kka2_1:8,P00552,,YES,121,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.552,-2.795,1.243,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.100394,0.00523326,0.616769 kka2_1:8_R121E,kka2_1:8_121,Kka2,kka2_1:8,P00552,,YES,121,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.552,-2.795,1.243,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.100394,0.00523326,0.616769 kka2_1:8_R121F,kka2_1:8_121,Kka2,kka2_1:8,P00552,,YES,121,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.552,-4.32,2.768,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.100394,0.00523326,0.570472 kka2_1:8_R121F,kka2_1:8_121,Kka2,kka2_1:8,P00552,,YES,121,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.552,-4.32,2.768,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.100394,0.00523326,0.570472 kka2_1:8_R121I,kka2_1:8_121,Kka2,kka2_1:8,P00552,,YES,121,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.552,-3.978,2.426,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.100394,0.00523326,0.531623 kka2_1:8_R121I,kka2_1:8_121,Kka2,kka2_1:8,P00552,,YES,121,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.552,-3.978,2.426,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.100394,0.00523326,0.531623 kka2_1:8_R121K,kka2_1:8_121,Kka2,kka2_1:8,P00552,,YES,121,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.552,-2.242,0.69,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.100394,0.00523326,0.709263 kka2_1:8_R121K,kka2_1:8_121,Kka2,kka2_1:8,P00552,,YES,121,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.552,-2.242,0.69,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.100394,0.00523326,0.709263 kka2_1:8_R121M,kka2_1:8_121,Kka2,kka2_1:8,P00552,,YES,121,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.552,-4.593,3.041,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.100394,0.00523326,0.590629 kka2_1:8_R121M,kka2_1:8_121,Kka2,kka2_1:8,P00552,,YES,121,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.552,-4.593,3.041,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.100394,0.00523326,0.590629 kka2_1:8_R121N,kka2_1:8_121,Kka2,kka2_1:8,P00552,,YES,121,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.552,-3.678,2.126,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.100394,0.00523326,0.599923 kka2_1:8_R121N,kka2_1:8_121,Kka2,kka2_1:8,P00552,,YES,121,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.552,-3.678,2.126,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.100394,0.00523326,0.599923 kka2_1:8_R121T,kka2_1:8_121,Kka2,kka2_1:8,P00552,,YES,121,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.552,-3.59,2.038,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.100394,0.00523326,0.618852 kka2_1:8_R121T,kka2_1:8_121,Kka2,kka2_1:8,P00552,,YES,121,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.552,-3.59,2.038,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.100394,0.00523326,0.618852 kka2_1:8_R121V,kka2_1:8_121,Kka2,kka2_1:8,P00552,,YES,121,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.552,-3.699,2.147,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.100394,0.00523326,0.608442 kka2_1:8_R121V,kka2_1:8_121,Kka2,kka2_1:8,P00552,,YES,121,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.552,-3.699,2.147,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.100394,0.00523326,0.608442 kka2_1:8_R121Y,kka2_1:8_121,Kka2,kka2_1:8,P00552,,YES,121,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.552,-4.18,2.628,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.100394,0.00523326,0.571379 kka2_1:8_R121Y,kka2_1:8_121,Kka2,kka2_1:8,P00552,,YES,121,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.552,-4.18,2.628,,0.517,H,A,1.2,0.89,1.412,,64.39,HBB,-2.53467,0.100394,0.00523326,0.571379 kka2_1:8_R122A,kka2_1:8_122,Kka2,kka2_1:8,P00552,,YES,122,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.175,-2.209,0.034,,0.487,H,A,1.2,0.26,22.675,22.675,71.59,BBH,-1.53833,0.100394,0.00736512,0.942943 kka2_1:8_R122A,kka2_1:8_122,Kka2,kka2_1:8,P00552,,YES,122,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.175,-2.209,0.034,,0.487,H,A,1.2,0.26,22.675,22.675,71.59,BBH,-1.53833,0.100394,0.00736512,0.942943 kka2_1:8_R122E,kka2_1:8_122,Kka2,kka2_1:8,P00552,,YES,122,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.175,-2.696,0.521,,0.487,H,A,1.2,0.26,22.675,22.675,71.59,BBH,-1.53833,0.100394,0.00736512,0.843118 kka2_1:8_R122E,kka2_1:8_122,Kka2,kka2_1:8,P00552,,YES,122,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-2.175,-2.696,0.521,,0.487,H,A,1.2,0.26,22.675,22.675,71.59,BBH,-1.53833,0.100394,0.00736512,0.843118 kka2_1:8_R122F,kka2_1:8_122,Kka2,kka2_1:8,P00552,,YES,122,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.175,-4.454,2.279,,0.487,H,A,1.2,0.26,22.675,22.675,71.59,BBH,-1.53833,0.100394,0.00736512,0.787342 kka2_1:8_R122F,kka2_1:8_122,Kka2,kka2_1:8,P00552,,YES,122,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-2.175,-4.454,2.279,,0.487,H,A,1.2,0.26,22.675,22.675,71.59,BBH,-1.53833,0.100394,0.00736512,0.787342 kka2_1:8_R122I,kka2_1:8_122,Kka2,kka2_1:8,P00552,,YES,122,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.175,-4.03,1.855,,0.487,H,A,1.2,0.26,22.675,22.675,71.59,BBH,-1.53833,0.100394,0.00736512,0.732324 kka2_1:8_R122I,kka2_1:8_122,Kka2,kka2_1:8,P00552,,YES,122,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-2.175,-4.03,1.855,,0.487,H,A,1.2,0.26,22.675,22.675,71.59,BBH,-1.53833,0.100394,0.00736512,0.732324 kka2_1:8_R122K,kka2_1:8_122,Kka2,kka2_1:8,P00552,,YES,122,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.175,-3.561,1.386,,0.487,H,A,1.2,0.26,22.675,22.675,71.59,BBH,-1.53833,0.100394,0.00736512,0.752479 kka2_1:8_R122K,kka2_1:8_122,Kka2,kka2_1:8,P00552,,YES,122,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.175,-3.561,1.386,,0.487,H,A,1.2,0.26,22.675,22.675,71.59,BBH,-1.53833,0.100394,0.00736512,0.752479 kka2_1:8_R122M,kka2_1:8_122,Kka2,kka2_1:8,P00552,,YES,122,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.175,-3.353,1.178,,0.487,H,A,1.2,0.26,22.675,22.675,71.59,BBH,-1.53833,0.100394,0.00736512,0.754398 kka2_1:8_R122M,kka2_1:8_122,Kka2,kka2_1:8,P00552,,YES,122,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.175,-3.353,1.178,,0.487,H,A,1.2,0.26,22.675,22.675,71.59,BBH,-1.53833,0.100394,0.00736512,0.754398 kka2_1:8_R122V,kka2_1:8_122,Kka2,kka2_1:8,P00552,,YES,122,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.175,-2.949,0.774,,0.487,H,A,1.2,0.26,22.675,22.675,71.59,BBH,-1.53833,0.100394,0.00736512,0.834444 kka2_1:8_R122V,kka2_1:8_122,Kka2,kka2_1:8,P00552,,YES,122,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-2.175,-2.949,0.774,,0.487,H,A,1.2,0.26,22.675,22.675,71.59,BBH,-1.53833,0.100394,0.00736512,0.834444 kka2_1:8_R122Y,kka2_1:8_122,Kka2,kka2_1:8,P00552,,YES,122,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.175,-4.411,2.236,,0.487,H,A,1.2,0.26,22.675,22.675,71.59,BBH,-1.53833,0.100394,0.00736512,0.785702 kka2_1:8_R122Y,kka2_1:8_122,Kka2,kka2_1:8,P00552,,YES,122,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.175,-4.411,2.236,,0.487,H,A,1.2,0.26,22.675,22.675,71.59,BBH,-1.53833,0.100394,0.00736512,0.785702 kka2_1:8_R140I,kka2_1:8_140,Kka2,kka2_1:8,P00552,,YES,140,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.351,-4.1,2.749,,0.12,H,A,0.16,0.2,2.874,,53.03,BBH,-1.885,0.100394,0.00430167,0.446312 kka2_1:8_R140I,kka2_1:8_140,Kka2,kka2_1:8,P00552,,YES,140,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.351,-4.1,2.749,,0.12,H,A,0.16,0.2,2.874,,53.03,BBH,-1.885,0.100394,0.00430167,0.446312 kka2_1:8_R143M,kka2_1:8_143,Kka2,kka2_1:8,P00552,,YES,143,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.525,-4.625,2.1,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.100394,0.00662247,0.76136 kka2_1:8_R143M,kka2_1:8_143,Kka2,kka2_1:8,P00552,,YES,143,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.525,-4.625,2.1,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.100394,0.00662247,0.76136 kka2_1:8_R143W,kka2_1:8_143,Kka2,kka2_1:8,P00552,,YES,143,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.525,-5.57,3.045,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.100394,0.00662247,0.760941 kka2_1:8_R143W,kka2_1:8_143,Kka2,kka2_1:8,P00552,,YES,143,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.525,-5.57,3.045,,0.325,H,A,1.2,1.22,1.777,,65.53,ABH,-1.86833,0.100394,0.00662247,0.760941 kka2_1:8_R145D,kka2_1:8_145,Kka2,kka2_1:8,P00552,,YES,145,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.804,-3.693,1.889,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.100394,0.00846663,0.613839 kka2_1:8_R145D,kka2_1:8_145,Kka2,kka2_1:8,P00552,,YES,145,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.804,-3.693,1.889,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.100394,0.00846663,0.613839 kka2_1:8_R145F,kka2_1:8_145,Kka2,kka2_1:8,P00552,,YES,145,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.804,-4.396,2.592,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.100394,0.00846663,0.644679 kka2_1:8_R145F,kka2_1:8_145,Kka2,kka2_1:8,P00552,,YES,145,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.804,-4.396,2.592,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.100394,0.00846663,0.644679 kka2_1:8_R145V,kka2_1:8_145,Kka2,kka2_1:8,P00552,,YES,145,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.804,-3.111,1.307,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.100394,0.00846663,0.650177 kka2_1:8_R145V,kka2_1:8_145,Kka2,kka2_1:8,P00552,,YES,145,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.804,-3.111,1.307,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.100394,0.00846663,0.650177 kka2_1:8_R145Y,kka2_1:8_145,Kka2,kka2_1:8,P00552,,YES,145,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.804,-4.267,2.463,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.100394,0.00846663,0.600982 kka2_1:8_R145Y,kka2_1:8_145,Kka2,kka2_1:8,P00552,,YES,145,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.804,-4.267,2.463,,0.346,H,A,0.16,1.23,7.961,,63.64,HBP,-1.88033,0.100394,0.00846663,0.600982 kka2_1:8_R147A,kka2_1:8_147,Kka2,kka2_1:8,P00552,,YES,147,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.123,-3.267,2.144,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.100394,0.00549168,0.558678 kka2_1:8_R147A,kka2_1:8_147,Kka2,kka2_1:8,P00552,,YES,147,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.123,-3.267,2.144,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.100394,0.00549168,0.558678 kka2_1:8_R147D,kka2_1:8_147,Kka2,kka2_1:8,P00552,,YES,147,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.123,-3.649,2.526,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.100394,0.00549168,0.503159 kka2_1:8_R147D,kka2_1:8_147,Kka2,kka2_1:8,P00552,,YES,147,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.123,-3.649,2.526,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.100394,0.00549168,0.503159 kka2_1:8_R147E,kka2_1:8_147,Kka2,kka2_1:8,P00552,,YES,147,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.123,-3.304,2.181,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.100394,0.00549168,0.548708 kka2_1:8_R147E,kka2_1:8_147,Kka2,kka2_1:8,P00552,,YES,147,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.123,-3.304,2.181,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.100394,0.00549168,0.548708 kka2_1:8_R147M,kka2_1:8_147,Kka2,kka2_1:8,P00552,,YES,147,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.123,-4.65,3.527,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.100394,0.00549168,0.513103 kka2_1:8_R147M,kka2_1:8_147,Kka2,kka2_1:8,P00552,,YES,147,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.123,-4.65,3.527,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.100394,0.00549168,0.513103 kka2_1:8_R147Y,kka2_1:8_147,Kka2,kka2_1:8,P00552,,YES,147,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.123,-4.044,2.921,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.100394,0.00549168,0.478968 kka2_1:8_R147Y,kka2_1:8_147,Kka2,kka2_1:8,P00552,,YES,147,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.123,-4.044,2.921,,0.094,H,A,1.2,0.97,1.582,,64.02,PBH,-1.98267,0.100394,0.00549168,0.478968 kka2_1:8_R18A,kka2_1:8_18,Kka2,kka2_1:8,P00552,,YES,18,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.055,-2.49,0.435,,0.474,T,A,1.2,0.54,19.629,19.629,71.59,ABH,-1.821,0.100394,0.00724065,0.869116 kka2_1:8_R18A,kka2_1:8_18,Kka2,kka2_1:8,P00552,,YES,18,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-2.055,-2.49,0.435,,0.474,T,A,1.2,0.54,19.629,19.629,71.59,ABH,-1.821,0.100394,0.00724065,0.869116 kka2_1:8_R18D,kka2_1:8_18,Kka2,kka2_1:8,P00552,,YES,18,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.055,-2.8,0.745,,0.474,T,A,1.2,0.54,19.629,19.629,71.59,ABH,-1.821,0.100394,0.00724065,0.821341 kka2_1:8_R18D,kka2_1:8_18,Kka2,kka2_1:8,P00552,,YES,18,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-2.055,-2.8,0.745,,0.474,T,A,1.2,0.54,19.629,19.629,71.59,ABH,-1.821,0.100394,0.00724065,0.821341 kka2_1:8_R18K,kka2_1:8_18,Kka2,kka2_1:8,P00552,,YES,18,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.055,-2.865,0.81,,0.474,T,A,1.2,0.54,19.629,19.629,71.59,ABH,-1.821,0.100394,0.00724065,0.889161 kka2_1:8_R18K,kka2_1:8_18,Kka2,kka2_1:8,P00552,,YES,18,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-2.055,-2.865,0.81,,0.474,T,A,1.2,0.54,19.629,19.629,71.59,ABH,-1.821,0.100394,0.00724065,0.889161 kka2_1:8_R202K,kka2_1:8_202,Kka2,kka2_1:8,P00552,,YES,202,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.761,-2.914,1.153,,0.607,E,B,1.2,0.48,1.409,,52.27,OBH,-1.41067,0.100394,0.00696498,0.673689 kka2_1:8_R202K,kka2_1:8_202,Kka2,kka2_1:8,P00552,,YES,202,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.761,-2.914,1.153,,0.607,E,B,1.2,0.48,1.409,,52.27,OBH,-1.41067,0.100394,0.00696498,0.673689 kka2_1:8_R202Y,kka2_1:8_202,Kka2,kka2_1:8,P00552,,YES,202,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.761,-4.316,2.555,,0.607,E,B,1.2,0.48,1.409,,52.27,OBH,-1.41067,0.100394,0.00696498,0.529947 kka2_1:8_R202Y,kka2_1:8_202,Kka2,kka2_1:8,P00552,,YES,202,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.761,-4.316,2.555,,0.607,E,B,1.2,0.48,1.409,,52.27,OBH,-1.41067,0.100394,0.00696498,0.529947 kka2_1:8_R211I,kka2_1:8_211,Kka2,kka2_1:8,P00552,,YES,211,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-0.899,-4.062,3.163,,0.12,T,a,0.16,-0.39,0.615,,49.62,OBH,-0.966,0.100394,0.00204888,0.426476 kka2_1:8_R211I,kka2_1:8_211,Kka2,kka2_1:8,P00552,,YES,211,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-0.899,-4.062,3.163,,0.12,T,a,0.16,-0.39,0.615,,49.62,OBH,-0.966,0.100394,0.00204888,0.426476 kka2_1:8_R239M,kka2_1:8_239,Kka2,kka2_1:8,P00552,,YES,239,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.949,-4.723,1.774,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.100394,0.00835326,0.729233 kka2_1:8_R239M,kka2_1:8_239,Kka2,kka2_1:8,P00552,,YES,239,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-2.949,-4.723,1.774,,0.15,H,A,1.2,-0.31,35.418,35.418,71.59,ABH,-2.23,0.100394,0.00835326,0.729233 kka2_1:8_R38A,kka2_1:8_38,Kka2,kka2_1:8,P00552,,YES,38,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.207,-3.17,1.963,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.100394,0.00372499,0.549466 kka2_1:8_R38A,kka2_1:8_38,Kka2,kka2_1:8,P00552,,YES,38,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.207,-3.17,1.963,,0.355,E,B,1.2,-1.13,0.387,,52.27,HBH,-1.28567,0.100394,0.00372499,0.549466 kka2_1:8_R44N,kka2_1:8_44,Kka2,kka2_1:8,P00552,,YES,44,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.062,-3.108,1.046,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.100394,0.00745043,0.655889 kka2_1:8_R44N,kka2_1:8_44,Kka2,kka2_1:8,P00552,,YES,44,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-2.062,-3.108,1.046,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.100394,0.00745043,0.655889 kka2_1:8_R44Y,kka2_1:8_44,Kka2,kka2_1:8,P00552,,YES,44,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.062,-4.366,2.304,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.100394,0.00745043,0.728039 kka2_1:8_R44Y,kka2_1:8_44,Kka2,kka2_1:8,P00552,,YES,44,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-2.062,-4.366,2.304,,0.487,S,B,0.16,-0.35,5.71,,71.59,OBO,-1.80767,0.100394,0.00745043,0.728039 kka2_1:8_R66D,kka2_1:8_66,Kka2,kka2_1:8,P00552,,YES,66,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-0.922,-3.72,2.798,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.100394,0.00161025,0.410117 kka2_1:8_R66D,kka2_1:8_66,Kka2,kka2_1:8,P00552,,YES,66,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-0.922,-3.72,2.798,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.100394,0.00161025,0.410117 kka2_1:8_R66F,kka2_1:8_66,Kka2,kka2_1:8,P00552,,YES,66,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-0.922,-4.355,3.433,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.100394,0.00161025,0.411499 kka2_1:8_R66F,kka2_1:8_66,Kka2,kka2_1:8,P00552,,YES,66,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-0.922,-4.355,3.433,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.100394,0.00161025,0.411499 kka2_1:8_R66G,kka2_1:8_66,Kka2,kka2_1:8,P00552,,YES,66,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-0.922,-3.421,2.499,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.100394,0.00161025,0.487048 kka2_1:8_R66G,kka2_1:8_66,Kka2,kka2_1:8,P00552,,YES,66,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-0.922,-3.421,2.499,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.100394,0.00161025,0.487048 kka2_1:8_R66I,kka2_1:8_66,Kka2,kka2_1:8,P00552,,YES,66,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-0.922,-4.073,3.151,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.100394,0.00161025,0.400656 kka2_1:8_R66I,kka2_1:8_66,Kka2,kka2_1:8,P00552,,YES,66,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-0.922,-4.073,3.151,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.100394,0.00161025,0.400656 kka2_1:8_R66M,kka2_1:8_66,Kka2,kka2_1:8,P00552,,YES,66,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-0.922,-4.542,3.62,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.100394,0.00161025,0.424351 kka2_1:8_R66M,kka2_1:8_66,Kka2,kka2_1:8,P00552,,YES,66,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-0.922,-4.542,3.62,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.100394,0.00161025,0.424351 kka2_1:8_R66N,kka2_1:8_66,Kka2,kka2_1:8,P00552,,YES,66,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-0.922,-3.51,2.588,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.100394,0.00161025,0.406118 kka2_1:8_R66N,kka2_1:8_66,Kka2,kka2_1:8,P00552,,YES,66,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-0.922,-3.51,2.588,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.100394,0.00161025,0.406118 kka2_1:8_R66P,kka2_1:8_66,Kka2,kka2_1:8,P00552,,YES,66,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-0.922,-3.906,2.984,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.100394,0.00161025,0.467421 kka2_1:8_R66P,kka2_1:8_66,Kka2,kka2_1:8,P00552,,YES,66,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-0.922,-3.906,2.984,,0.103,H,A,1.2,-0.2,0.216,,46.21,HBH,-1.13567,0.100394,0.00161025,0.467421 kka2_1:8_R89A,kka2_1:8_89,Kka2,kka2_1:8,P00552,,YES,89,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.548,-2.806,1.258,,0.209,E,B,1.2,1.41,25.3,25.3,64.39,OBA,-1.89867,0.100394,0.00524373,0.634685 kka2_1:8_R89A,kka2_1:8_89,Kka2,kka2_1:8,P00552,,YES,89,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.548,-2.806,1.258,,0.209,E,B,1.2,1.41,25.3,25.3,64.39,OBA,-1.89867,0.100394,0.00524373,0.634685 kka2_1:8_R89D,kka2_1:8_89,Kka2,kka2_1:8,P00552,,YES,89,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.548,-3.735,2.187,,0.209,E,B,1.2,1.41,25.3,25.3,64.39,OBA,-1.89867,0.100394,0.00524373,0.539608 kka2_1:8_R89D,kka2_1:8_89,Kka2,kka2_1:8,P00552,,YES,89,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.548,-3.735,2.187,,0.209,E,B,1.2,1.41,25.3,25.3,64.39,OBA,-1.89867,0.100394,0.00524373,0.539608 kka2_1:8_R89E,kka2_1:8_89,Kka2,kka2_1:8,P00552,,YES,89,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.548,-2.88,1.332,,0.209,E,B,1.2,1.41,25.3,25.3,64.39,OBA,-1.89867,0.100394,0.00524373,0.615576 kka2_1:8_R89E,kka2_1:8_89,Kka2,kka2_1:8,P00552,,YES,89,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.548,-2.88,1.332,,0.209,E,B,1.2,1.41,25.3,25.3,64.39,OBA,-1.89867,0.100394,0.00524373,0.615576 kka2_1:8_R89F,kka2_1:8_89,Kka2,kka2_1:8,P00552,,YES,89,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.548,-3.236,1.688,,0.209,E,B,1.2,1.41,25.3,25.3,64.39,OBA,-1.89867,0.100394,0.00524373,0.579129 kka2_1:8_R89F,kka2_1:8_89,Kka2,kka2_1:8,P00552,,YES,89,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.548,-3.236,1.688,,0.209,E,B,1.2,1.41,25.3,25.3,64.39,OBA,-1.89867,0.100394,0.00524373,0.579129 kka2_1:8_R89I,kka2_1:8_89,Kka2,kka2_1:8,P00552,,YES,89,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.548,-4.125,2.577,,0.209,E,B,1.2,1.41,25.3,25.3,64.39,OBA,-1.89867,0.100394,0.00524373,0.504186 kka2_1:8_R89I,kka2_1:8_89,Kka2,kka2_1:8,P00552,,YES,89,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.548,-4.125,2.577,,0.209,E,B,1.2,1.41,25.3,25.3,64.39,OBA,-1.89867,0.100394,0.00524373,0.504186 kka2_1:8_R89K,kka2_1:8_89,Kka2,kka2_1:8,P00552,,YES,89,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.548,-2.811,1.263,,0.209,E,B,1.2,1.41,25.3,25.3,64.39,OBA,-1.89867,0.100394,0.00524373,0.650106 kka2_1:8_R89K,kka2_1:8_89,Kka2,kka2_1:8,P00552,,YES,89,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.548,-2.811,1.263,,0.209,E,B,1.2,1.41,25.3,25.3,64.39,OBA,-1.89867,0.100394,0.00524373,0.650106 kka2_1:8_R89M,kka2_1:8_89,Kka2,kka2_1:8,P00552,,YES,89,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.548,-4.745,3.197,,0.209,E,B,1.2,1.41,25.3,25.3,64.39,OBA,-1.89867,0.100394,0.00524373,0.549169 kka2_1:8_R89M,kka2_1:8_89,Kka2,kka2_1:8,P00552,,YES,89,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.548,-4.745,3.197,,0.209,E,B,1.2,1.41,25.3,25.3,64.39,OBA,-1.89867,0.100394,0.00524373,0.549169 kka2_1:8_R89P,kka2_1:8_89,Kka2,kka2_1:8,P00552,,YES,89,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.548,-4.076,2.528,,0.209,E,B,1.2,1.41,25.3,25.3,64.39,OBA,-1.89867,0.100394,0.00524373,0.538152 kka2_1:8_R89P,kka2_1:8_89,Kka2,kka2_1:8,P00552,,YES,89,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.548,-4.076,2.528,,0.209,E,B,1.2,1.41,25.3,25.3,64.39,OBA,-1.89867,0.100394,0.00524373,0.538152 kka2_1:8_R89Q,kka2_1:8_89,Kka2,kka2_1:8,P00552,,YES,89,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.548,-2.675,1.127,,0.209,E,B,1.2,1.41,25.3,25.3,64.39,OBA,-1.89867,0.100394,0.00524373,0.677912 kka2_1:8_R89Q,kka2_1:8_89,Kka2,kka2_1:8,P00552,,YES,89,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.548,-2.675,1.127,,0.209,E,B,1.2,1.41,25.3,25.3,64.39,OBA,-1.89867,0.100394,0.00524373,0.677912 kka2_1:8_R89T,kka2_1:8_89,Kka2,kka2_1:8,P00552,,YES,89,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.548,-2.992,1.444,,0.209,E,B,1.2,1.41,25.3,25.3,64.39,OBA,-1.89867,0.100394,0.00524373,0.609395 kka2_1:8_R89T,kka2_1:8_89,Kka2,kka2_1:8,P00552,,YES,89,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.548,-2.992,1.444,,0.209,E,B,1.2,1.41,25.3,25.3,64.39,OBA,-1.89867,0.100394,0.00524373,0.609395 kka2_1:8_R89V,kka2_1:8_89,Kka2,kka2_1:8,P00552,,YES,89,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.548,-3.804,2.256,,0.209,E,B,1.2,1.41,25.3,25.3,64.39,OBA,-1.89867,0.100394,0.00524373,0.568303 kka2_1:8_R89V,kka2_1:8_89,Kka2,kka2_1:8,P00552,,YES,89,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.548,-3.804,2.256,,0.209,E,B,1.2,1.41,25.3,25.3,64.39,OBA,-1.89867,0.100394,0.00524373,0.568303 kka2_1:8_R89W,kka2_1:8_89,Kka2,kka2_1:8,P00552,,YES,89,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.548,-5.305,3.757,,0.209,E,B,1.2,1.41,25.3,25.3,64.39,OBA,-1.89867,0.100394,0.00524373,0.549819 kka2_1:8_R89W,kka2_1:8_89,Kka2,kka2_1:8,P00552,,YES,89,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.548,-5.305,3.757,,0.209,E,B,1.2,1.41,25.3,25.3,64.39,OBA,-1.89867,0.100394,0.00524373,0.549819 kka2_1:8_R89Y,kka2_1:8_89,Kka2,kka2_1:8,P00552,,YES,89,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.548,-2.904,1.356,,0.209,E,B,1.2,1.41,25.3,25.3,64.39,OBA,-1.89867,0.100394,0.00524373,0.634808 kka2_1:8_R89Y,kka2_1:8_89,Kka2,kka2_1:8,P00552,,YES,89,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.548,-2.904,1.356,,0.209,E,B,1.2,1.41,25.3,25.3,64.39,OBA,-1.89867,0.100394,0.00524373,0.634808 kka2_1:8_S104F,kka2_1:8_104,Kka2,kka2_1:8,P00552,,YES,104,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.436,-4.301,2.865,,0.536,T,A,0.27,-1.11,1.689,,63.64,HPP,-1.91433,0.100394,0.00555207,0.501246 kka2_1:8_S104F,kka2_1:8_104,Kka2,kka2_1:8,P00552,,YES,104,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-1.436,-4.301,2.865,,0.536,T,A,0.27,-1.11,1.689,,63.64,HPP,-1.91433,0.100394,0.00555207,0.501246 kka2_1:8_S104H,kka2_1:8_104,Kka2,kka2_1:8,P00552,,YES,104,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.436,-3.319,1.883,,0.536,T,A,0.27,-1.11,1.689,,63.64,HPP,-1.91433,0.100394,0.00555207,0.542259 kka2_1:8_S104H,kka2_1:8_104,Kka2,kka2_1:8,P00552,,YES,104,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-1.436,-3.319,1.883,,0.536,T,A,0.27,-1.11,1.689,,63.64,HPP,-1.91433,0.100394,0.00555207,0.542259 kka2_1:8_S104M,kka2_1:8_104,Kka2,kka2_1:8,P00552,,YES,104,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.436,-4.687,3.251,,0.536,T,A,0.27,-1.11,1.689,,63.64,HPP,-1.91433,0.100394,0.00555207,0.552698 kka2_1:8_S104M,kka2_1:8_104,Kka2,kka2_1:8,P00552,,YES,104,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.436,-4.687,3.251,,0.536,T,A,0.27,-1.11,1.689,,63.64,HPP,-1.91433,0.100394,0.00555207,0.552698 kka2_1:8_S105D,kka2_1:8_105,Kka2,kka2_1:8,P00552,,YES,105,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.945,-2.638,0.693,,0.056,S,B,0.27,-1.04,2.115,,65.53,PPB,-2.17033,0.100394,0.00847233,0.565202 kka2_1:8_S105D,kka2_1:8_105,Kka2,kka2_1:8,P00552,,YES,105,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-1.945,-2.638,0.693,,0.056,S,B,0.27,-1.04,2.115,,65.53,PPB,-2.17033,0.100394,0.00847233,0.565202 kka2_1:8_S105V,kka2_1:8_105,Kka2,kka2_1:8,P00552,,YES,105,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.945,-2.997,1.052,,0.056,S,B,0.27,-1.04,2.115,,65.53,PPB,-2.17033,0.100394,0.00847233,0.472954 kka2_1:8_S105V,kka2_1:8_105,Kka2,kka2_1:8,P00552,,YES,105,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-1.945,-2.997,1.052,,0.056,S,B,0.27,-1.04,2.115,,65.53,PPB,-2.17033,0.100394,0.00847233,0.472954 kka2_1:8_S105W,kka2_1:8_105,Kka2,kka2_1:8,P00552,,YES,105,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.945,-5.544,3.599,,0.056,S,B,0.27,-1.04,2.115,,65.53,PPB,-2.17033,0.100394,0.00847233,0.477836 kka2_1:8_S105W,kka2_1:8_105,Kka2,kka2_1:8,P00552,,YES,105,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-1.945,-5.544,3.599,,0.056,S,B,0.27,-1.04,2.115,,65.53,PPB,-2.17033,0.100394,0.00847233,0.477836 kka2_1:8_S105Y,kka2_1:8_105,Kka2,kka2_1:8,P00552,,YES,105,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.945,-4.433,2.488,,0.056,S,B,0.27,-1.04,2.115,,65.53,PPB,-2.17033,0.100394,0.00847233,0.497998 kka2_1:8_S105Y,kka2_1:8_105,Kka2,kka2_1:8,P00552,,YES,105,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.945,-4.433,2.488,,0.056,S,B,0.27,-1.04,2.115,,65.53,PPB,-2.17033,0.100394,0.00847233,0.497998 kka2_1:8_S114A,kka2_1:8_114,Kka2,kka2_1:8,P00552,,YES,114,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.527,-2.102,-0.425,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.100394,0.00705262,1.03533 kka2_1:8_S114A,kka2_1:8_114,Kka2,kka2_1:8,P00552,,YES,114,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.527,-2.102,-0.425,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.100394,0.00705262,1.03533 kka2_1:8_S114P,kka2_1:8_114,Kka2,kka2_1:8,P00552,,YES,114,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.527,-4.051,1.524,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.100394,0.00705262,0.600639 kka2_1:8_S114P,kka2_1:8_114,Kka2,kka2_1:8,P00552,,YES,114,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.527,-4.051,1.524,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.100394,0.00705262,0.600639 kka2_1:8_S114V,kka2_1:8_114,Kka2,kka2_1:8,P00552,,YES,114,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.527,-2.736,0.209,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.100394,0.00705262,0.840626 kka2_1:8_S114V,kka2_1:8_114,Kka2,kka2_1:8,P00552,,YES,114,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.527,-2.736,0.209,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.100394,0.00705262,0.840626 kka2_1:8_S114Y,kka2_1:8_114,Kka2,kka2_1:8,P00552,,YES,114,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.527,-4.358,1.831,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.100394,0.00705262,0.74107 kka2_1:8_S114Y,kka2_1:8_114,Kka2,kka2_1:8,P00552,,YES,114,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.527,-4.358,1.831,,0.192,H,A,0.27,-1.04,19.235,19.235,71.59,HPH,-1.78867,0.100394,0.00705262,0.74107 kka2_1:8_S11D,kka2_1:8_11,Kka2,kka2_1:8,P00552,,YES,11,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.322,-3.766,1.444,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.100394,0.00381691,0.791392 kka2_1:8_S11D,kka2_1:8_11,Kka2,kka2_1:8,P00552,,YES,11,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.322,-3.766,1.444,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.100394,0.00381691,0.791392 kka2_1:8_S11E,kka2_1:8_11,Kka2,kka2_1:8,P00552,,YES,11,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.322,-3.629,1.307,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.100394,0.00381691,0.815689 kka2_1:8_S11E,kka2_1:8_11,Kka2,kka2_1:8,P00552,,YES,11,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.322,-3.629,1.307,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.100394,0.00381691,0.815689 kka2_1:8_S11F,kka2_1:8_11,Kka2,kka2_1:8,P00552,,YES,11,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.322,-3.896,1.574,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.100394,0.00381691,0.821959 kka2_1:8_S11F,kka2_1:8_11,Kka2,kka2_1:8,P00552,,YES,11,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.322,-3.896,1.574,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.100394,0.00381691,0.821959 kka2_1:8_S11H,kka2_1:8_11,Kka2,kka2_1:8,P00552,,YES,11,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.322,-4.78,2.458,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.100394,0.00381691,0.812924 kka2_1:8_S11H,kka2_1:8_11,Kka2,kka2_1:8,P00552,,YES,11,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.322,-4.78,2.458,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.100394,0.00381691,0.812924 kka2_1:8_S11K,kka2_1:8_11,Kka2,kka2_1:8,P00552,,YES,11,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.322,-3.575,1.253,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.100394,0.00381691,0.852624 kka2_1:8_S11K,kka2_1:8_11,Kka2,kka2_1:8,P00552,,YES,11,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.322,-3.575,1.253,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.100394,0.00381691,0.852624 kka2_1:8_S11V,kka2_1:8_11,Kka2,kka2_1:8,P00552,,YES,11,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.322,-2.388,0.066,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.100394,0.00381691,0.940496 kka2_1:8_S11V,kka2_1:8_11,Kka2,kka2_1:8,P00552,,YES,11,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.322,-2.388,0.066,,0.408,,B,0.77,1.64,,,92.05,OPO,-1.69867,0.100394,0.00381691,0.940496 kka2_1:8_S204P,kka2_1:8_204,Kka2,kka2_1:8,P00552,,YES,204,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.353,-3.82,2.467,,0.144,E,A,0.27,-1.2,0.368,,65.53,HPO,-0.953333,0.100394,0.00881794,0.473688 kka2_1:8_S204P,kka2_1:8_204,Kka2,kka2_1:8,P00552,,YES,204,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-1.353,-3.82,2.467,,0.144,E,A,0.27,-1.2,0.368,,65.53,HPO,-0.953333,0.100394,0.00881794,0.473688 kka2_1:8_S204Q,kka2_1:8_204,Kka2,kka2_1:8,P00552,,YES,204,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.353,-3.954,2.601,,0.144,E,A,0.27,-1.2,0.368,,65.53,HPO,-0.953333,0.100394,0.00881794,0.462898 kka2_1:8_S204Q,kka2_1:8_204,Kka2,kka2_1:8,P00552,,YES,204,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.353,-3.954,2.601,,0.144,E,A,0.27,-1.2,0.368,,65.53,HPO,-0.953333,0.100394,0.00881794,0.462898 kka2_1:8_S204Y,kka2_1:8_204,Kka2,kka2_1:8,P00552,,YES,204,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.353,-4.328,2.975,,0.144,E,A,0.27,-1.2,0.368,,65.53,HPO,-0.953333,0.100394,0.00881794,0.48999 kka2_1:8_S204Y,kka2_1:8_204,Kka2,kka2_1:8,P00552,,YES,204,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-1.353,-4.328,2.975,,0.144,E,A,0.27,-1.2,0.368,,65.53,HPO,-0.953333,0.100394,0.00881794,0.48999 kka2_1:8_S251A,kka2_1:8_251,Kka2,kka2_1:8,P00552,,YES,251,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.636,-2.138,-0.498,,0.712,H,A,0.27,-0.25,,,71.59,APP,-2.09367,0.100394,0.0138916,1.05919 kka2_1:8_S251A,kka2_1:8_251,Kka2,kka2_1:8,P00552,,YES,251,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.636,-2.138,-0.498,,0.712,H,A,0.27,-0.25,,,71.59,APP,-2.09367,0.100394,0.0138916,1.05919 kka2_1:8_S251Q,kka2_1:8_251,Kka2,kka2_1:8,P00552,,YES,251,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.636,-2.668,0.032,,0.712,H,A,0.27,-0.25,,,71.59,APP,-2.09367,0.100394,0.0138916,0.993736 kka2_1:8_S251Q,kka2_1:8_251,Kka2,kka2_1:8,P00552,,YES,251,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.636,-2.668,0.032,,0.712,H,A,0.27,-0.25,,,71.59,APP,-2.09367,0.100394,0.0138916,0.993736 kka2_1:8_S32D,kka2_1:8_32,Kka2,kka2_1:8,P00552,,YES,32,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-0.804,-3.272,2.468,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.100394,0.00149998,0.427788 kka2_1:8_S32D,kka2_1:8_32,Kka2,kka2_1:8,P00552,,YES,32,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-0.804,-3.272,2.468,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.100394,0.00149998,0.427788 kka2_1:8_S32W,kka2_1:8_32,Kka2,kka2_1:8,P00552,,YES,32,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-0.804,-5.351,4.547,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.100394,0.00149998,0.459175 kka2_1:8_S32W,kka2_1:8_32,Kka2,kka2_1:8,P00552,,YES,32,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-0.804,-5.351,4.547,,0.768,S,b,0.77,3.75,,,,OPA,-1.74533,0.100394,0.00149998,0.459175 kka2_1:8_S40F,kka2_1:8_40,Kka2,kka2_1:8,P00552,,YES,40,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.645,-4.453,1.808,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.100394,0.00693477,0.765487 kka2_1:8_S40F,kka2_1:8_40,Kka2,kka2_1:8,P00552,,YES,40,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.645,-4.453,1.808,,0.32,E,B,0.27,-0.9,19.115,19.115,71.59,HPH,-1.91567,0.100394,0.00693477,0.765487 kka2_1:8_S54A,kka2_1:8_54,Kka2,kka2_1:8,P00552,,YES,54,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.471,-1.705,-0.766,,0.408,S,b,0.77,1.01,13.679,13.679,71.59,HPO,-2.259,0.100394,0.00782867,0.99132 kka2_1:8_S54A,kka2_1:8_54,Kka2,kka2_1:8,P00552,,YES,54,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.471,-1.705,-0.766,,0.408,S,b,0.77,1.01,13.679,13.679,71.59,HPO,-2.259,0.100394,0.00782867,0.99132 kka2_1:8_S54D,kka2_1:8_54,Kka2,kka2_1:8,P00552,,YES,54,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.471,-2.887,0.416,,0.408,S,b,0.77,1.01,13.679,13.679,71.59,HPO,-2.259,0.100394,0.00782867,0.768439 kka2_1:8_S54D,kka2_1:8_54,Kka2,kka2_1:8,P00552,,YES,54,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.471,-2.887,0.416,,0.408,S,b,0.77,1.01,13.679,13.679,71.59,HPO,-2.259,0.100394,0.00782867,0.768439 kka2_1:8_S54E,kka2_1:8_54,Kka2,kka2_1:8,P00552,,YES,54,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.471,-3.63,1.159,,0.408,S,b,0.77,1.01,13.679,13.679,71.59,HPO,-2.259,0.100394,0.00782867,0.792304 kka2_1:8_S54E,kka2_1:8_54,Kka2,kka2_1:8,P00552,,YES,54,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.471,-3.63,1.159,,0.408,S,b,0.77,1.01,13.679,13.679,71.59,HPO,-2.259,0.100394,0.00782867,0.792304 kka2_1:8_S54F,kka2_1:8_54,Kka2,kka2_1:8,P00552,,YES,54,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.471,-4.27,1.799,,0.408,S,b,0.77,1.01,13.679,13.679,71.59,HPO,-2.259,0.100394,0.00782867,0.778591 kka2_1:8_S54F,kka2_1:8_54,Kka2,kka2_1:8,P00552,,YES,54,S,F,SF,Polar,Hydrophobic,5.68,3.32051,-2.35949,155,105,165,60,89,189.9,100.9,-2.471,-4.27,1.799,,0.408,S,b,0.77,1.01,13.679,13.679,71.59,HPO,-2.259,0.100394,0.00782867,0.778591 kka2_1:8_S54H,kka2_1:8_54,Kka2,kka2_1:8,P00552,,YES,54,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.471,-3.515,1.044,,0.408,S,b,0.77,1.01,13.679,13.679,71.59,HPO,-2.259,0.100394,0.00782867,0.84075 kka2_1:8_S54H,kka2_1:8_54,Kka2,kka2_1:8,P00552,,YES,54,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.471,-3.515,1.044,,0.408,S,b,0.77,1.01,13.679,13.679,71.59,HPO,-2.259,0.100394,0.00782867,0.84075 kka2_1:8_S54L,kka2_1:8_54,Kka2,kka2_1:8,P00552,,YES,54,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.471,-2.689,0.218,,0.408,S,b,0.77,1.01,13.679,13.679,71.59,HPO,-2.259,0.100394,0.00782867,0.818591 kka2_1:8_S54L,kka2_1:8_54,Kka2,kka2_1:8,P00552,,YES,54,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.471,-2.689,0.218,,0.408,S,b,0.77,1.01,13.679,13.679,71.59,HPO,-2.259,0.100394,0.00782867,0.818591 kka2_1:8_S54P,kka2_1:8_54,Kka2,kka2_1:8,P00552,,YES,54,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.471,-4.062,1.591,,0.408,S,b,0.77,1.01,13.679,13.679,71.59,HPO,-2.259,0.100394,0.00782867,0.692649 kka2_1:8_S54P,kka2_1:8_54,Kka2,kka2_1:8,P00552,,YES,54,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.471,-4.062,1.591,,0.408,S,b,0.77,1.01,13.679,13.679,71.59,HPO,-2.259,0.100394,0.00782867,0.692649 kka2_1:8_S54Q,kka2_1:8_54,Kka2,kka2_1:8,P00552,,YES,54,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.471,-3.041,0.57,,0.408,S,b,0.77,1.01,13.679,13.679,71.59,HPO,-2.259,0.100394,0.00782867,0.820311 kka2_1:8_S54Q,kka2_1:8_54,Kka2,kka2_1:8,P00552,,YES,54,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.471,-3.041,0.57,,0.408,S,b,0.77,1.01,13.679,13.679,71.59,HPO,-2.259,0.100394,0.00782867,0.820311 kka2_1:8_S54V,kka2_1:8_54,Kka2,kka2_1:8,P00552,,YES,54,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.471,-2.309,-0.162,,0.408,S,b,0.77,1.01,13.679,13.679,71.59,HPO,-2.259,0.100394,0.00782867,0.908473 kka2_1:8_S54V,kka2_1:8_54,Kka2,kka2_1:8,P00552,,YES,54,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.471,-2.309,-0.162,,0.408,S,b,0.77,1.01,13.679,13.679,71.59,HPO,-2.259,0.100394,0.00782867,0.908473 kka2_1:8_S68A,kka2_1:8_68,Kka2,kka2_1:8,P00552,,YES,68,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.623,-3.303,0.68,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.100394,0.00608265,0.851739 kka2_1:8_S68A,kka2_1:8_68,Kka2,kka2_1:8,P00552,,YES,68,S,A,SA,Polar,Hydrophobic,5.68,6,0.32,99,105,89,-16,89,88.6,-0.4,-2.623,-3.303,0.68,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.100394,0.00608265,0.851739 kka2_1:8_S68D,kka2_1:8_68,Kka2,kka2_1:8,P00552,,YES,68,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.623,-2.48,-0.143,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.100394,0.00608265,0.881015 kka2_1:8_S68D,kka2_1:8_68,Kka2,kka2_1:8,P00552,,YES,68,S,D,SD,Polar,negativeCharge,5.68,5.0516,-0.6284,65,105,133,28,89,111.1,22.1,-2.623,-2.48,-0.143,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.100394,0.00608265,0.881015 kka2_1:8_S68E,kka2_1:8_68,Kka2,kka2_1:8,P00552,,YES,68,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.623,-2.442,-0.181,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.100394,0.00608265,0.909797 kka2_1:8_S68E,kka2_1:8_68,Kka2,kka2_1:8,P00552,,YES,68,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-2.623,-2.442,-0.181,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.100394,0.00608265,0.909797 kka2_1:8_S68H,kka2_1:8_68,Kka2,kka2_1:8,P00552,,YES,68,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.623,-3.15,0.527,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.100394,0.00608265,0.866155 kka2_1:8_S68H,kka2_1:8_68,Kka2,kka2_1:8,P00552,,YES,68,S,H,SH,Polar,PositiveCharge,5.68,7.59,1.91,89,105,155,50,89,153.2,64.2,-2.623,-3.15,0.527,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.100394,0.00608265,0.866155 kka2_1:8_S68K,kka2_1:8_68,Kka2,kka2_1:8,P00552,,YES,68,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.623,-2.899,0.276,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.100394,0.00608265,0.883077 kka2_1:8_S68K,kka2_1:8_68,Kka2,kka2_1:8,P00552,,YES,68,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-2.623,-2.899,0.276,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.100394,0.00608265,0.883077 kka2_1:8_S68L,kka2_1:8_68,Kka2,kka2_1:8,P00552,,YES,68,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.623,-2.822,0.199,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.100394,0.00608265,0.86546 kka2_1:8_S68L,kka2_1:8_68,Kka2,kka2_1:8,P00552,,YES,68,S,L,SL,Polar,Hydrophobic,5.68,9.7088,4.0288,145,105,131,26,89,166.7,77.7,-2.623,-2.822,0.199,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.100394,0.00608265,0.86546 kka2_1:8_S68M,kka2_1:8_68,Kka2,kka2_1:8,P00552,,YES,68,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.623,-4.761,2.138,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.100394,0.00608265,0.838585 kka2_1:8_S68M,kka2_1:8_68,Kka2,kka2_1:8,P00552,,YES,68,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-2.623,-4.761,2.138,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.100394,0.00608265,0.838585 kka2_1:8_S68P,kka2_1:8_68,Kka2,kka2_1:8,P00552,,YES,68,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.623,-4.076,1.453,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.100394,0.00608265,0.706916 kka2_1:8_S68P,kka2_1:8_68,Kka2,kka2_1:8,P00552,,YES,68,S,P,SP,Polar,Special,5.68,6.3,0.62,74,105,115,10,89,112.7,23.7,-2.623,-4.076,1.453,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.100394,0.00608265,0.706916 kka2_1:8_S68Q,kka2_1:8_68,Kka2,kka2_1:8,P00552,,YES,68,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.623,-2.944,0.321,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.100394,0.00608265,0.875782 kka2_1:8_S68Q,kka2_1:8_68,Kka2,kka2_1:8,P00552,,YES,68,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.623,-2.944,0.321,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.100394,0.00608265,0.875782 kka2_1:8_S68V,kka2_1:8_68,Kka2,kka2_1:8,P00552,,YES,68,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.623,-3.127,0.504,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.100394,0.00608265,0.840033 kka2_1:8_S68V,kka2_1:8_68,Kka2,kka2_1:8,P00552,,YES,68,S,V,SV,Polar,Hydrophobic,5.68,5.60847,-0.0715347,124,105,117,12,89,140,51,-2.623,-3.127,0.504,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.100394,0.00608265,0.840033 kka2_1:8_S68W,kka2_1:8_68,Kka2,kka2_1:8,P00552,,YES,68,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.623,-5.546,2.923,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.100394,0.00608265,0.79465 kka2_1:8_S68W,kka2_1:8_68,Kka2,kka2_1:8,P00552,,YES,68,S,W,SW,Polar,Hydrophobic,5.68,5.89,0.21,177,105,204,99,89,227.8,138.8,-2.623,-5.546,2.923,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.100394,0.00608265,0.79465 kka2_1:8_S68Y,kka2_1:8_68,Kka2,kka2_1:8,P00552,,YES,68,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.623,-4.344,1.721,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.100394,0.00608265,0.766384 kka2_1:8_S68Y,kka2_1:8_68,Kka2,kka2_1:8,P00552,,YES,68,S,Y,SY,Polar,Hydrophobic,5.68,5.66,-0.02,144,105,181,76,89,193.6,104.6,-2.623,-4.344,1.721,,0.48,H,A,0.77,-0.1,,,71.59,HPH,-1.40767,0.100394,0.00608265,0.766384 kka2_1:8_T125D,kka2_1:8_125,Kka2,kka2_1:8,P00552,,YES,125,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.622,-2.647,0.025,,0.791,T,A,0.22,0.33,2.675,,92.05,BPH,-1.56933,0.100394,0.00821755,0.85492 kka2_1:8_T125D,kka2_1:8_125,Kka2,kka2_1:8,P00552,,YES,125,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.622,-2.647,0.025,,0.791,T,A,0.22,0.33,2.675,,92.05,BPH,-1.56933,0.100394,0.00821755,0.85492 kka2_1:8_T125E,kka2_1:8_125,Kka2,kka2_1:8,P00552,,YES,125,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.622,-2.741,0.119,,0.791,T,A,0.22,0.33,2.675,,92.05,BPH,-1.56933,0.100394,0.00821755,0.834825 kka2_1:8_T125E,kka2_1:8_125,Kka2,kka2_1:8,P00552,,YES,125,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.622,-2.741,0.119,,0.791,T,A,0.22,0.33,2.675,,92.05,BPH,-1.56933,0.100394,0.00821755,0.834825 kka2_1:8_T125H,kka2_1:8_125,Kka2,kka2_1:8,P00552,,YES,125,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.622,-4.735,2.113,,0.791,T,A,0.22,0.33,2.675,,92.05,BPH,-1.56933,0.100394,0.00821755,0.890627 kka2_1:8_T125H,kka2_1:8_125,Kka2,kka2_1:8,P00552,,YES,125,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.622,-4.735,2.113,,0.791,T,A,0.22,0.33,2.675,,92.05,BPH,-1.56933,0.100394,0.00821755,0.890627 kka2_1:8_T125Q,kka2_1:8_125,Kka2,kka2_1:8,P00552,,YES,125,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.622,-2.465,-0.157,,0.791,T,A,0.22,0.33,2.675,,92.05,BPH,-1.56933,0.100394,0.00821755,0.875548 kka2_1:8_T125Q,kka2_1:8_125,Kka2,kka2_1:8,P00552,,YES,125,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.622,-2.465,-0.157,,0.791,T,A,0.22,0.33,2.675,,92.05,BPH,-1.56933,0.100394,0.00821755,0.875548 kka2_1:8_T125R,kka2_1:8_125,Kka2,kka2_1:8,P00552,,YES,125,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.622,-2.191,-0.431,,0.791,T,A,0.22,0.33,2.675,,92.05,BPH,-1.56933,0.100394,0.00821755,0.932887 kka2_1:8_T125R,kka2_1:8_125,Kka2,kka2_1:8,P00552,,YES,125,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.622,-2.191,-0.431,,0.791,T,A,0.22,0.33,2.675,,92.05,BPH,-1.56933,0.100394,0.00821755,0.932887 kka2_1:8_T125W,kka2_1:8_125,Kka2,kka2_1:8,P00552,,YES,125,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.622,-5.542,2.92,,0.791,T,A,0.22,0.33,2.675,,92.05,BPH,-1.56933,0.100394,0.00821755,0.832514 kka2_1:8_T125W,kka2_1:8_125,Kka2,kka2_1:8,P00552,,YES,125,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.622,-5.542,2.92,,0.791,T,A,0.22,0.33,2.675,,92.05,BPH,-1.56933,0.100394,0.00821755,0.832514 kka2_1:8_T130D,kka2_1:8_130,Kka2,kka2_1:8,P00552,,YES,130,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.392,-2.708,0.316,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.100394,0.00804204,0.761873 kka2_1:8_T130D,kka2_1:8_130,Kka2,kka2_1:8,P00552,,YES,130,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.392,-2.708,0.316,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.100394,0.00804204,0.761873 kka2_1:8_T130E,kka2_1:8_130,Kka2,kka2_1:8,P00552,,YES,130,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.392,-3.049,0.657,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.100394,0.00804204,0.756474 kka2_1:8_T130E,kka2_1:8_130,Kka2,kka2_1:8,P00552,,YES,130,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.392,-3.049,0.657,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.100394,0.00804204,0.756474 kka2_1:8_T130F,kka2_1:8_130,Kka2,kka2_1:8,P00552,,YES,130,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.392,-4.384,1.992,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.100394,0.00804204,0.832351 kka2_1:8_T130F,kka2_1:8_130,Kka2,kka2_1:8,P00552,,YES,130,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.392,-4.384,1.992,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.100394,0.00804204,0.832351 kka2_1:8_T130G,kka2_1:8_130,Kka2,kka2_1:8,P00552,,YES,130,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.392,-2.278,-0.114,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.100394,0.00804204,0.826008 kka2_1:8_T130G,kka2_1:8_130,Kka2,kka2_1:8,P00552,,YES,130,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.392,-2.278,-0.114,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.100394,0.00804204,0.826008 kka2_1:8_T130L,kka2_1:8_130,Kka2,kka2_1:8,P00552,,YES,130,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.392,-2.848,0.456,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.100394,0.00804204,0.769406 kka2_1:8_T130L,kka2_1:8_130,Kka2,kka2_1:8,P00552,,YES,130,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.392,-2.848,0.456,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.100394,0.00804204,0.769406 kka2_1:8_T130Q,kka2_1:8_130,Kka2,kka2_1:8,P00552,,YES,130,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.392,-3.316,0.924,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.100394,0.00804204,0.79947 kka2_1:8_T130Q,kka2_1:8_130,Kka2,kka2_1:8,P00552,,YES,130,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.392,-3.316,0.924,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.100394,0.00804204,0.79947 kka2_1:8_T130R,kka2_1:8_130,Kka2,kka2_1:8,P00552,,YES,130,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.392,-3.981,1.589,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.100394,0.00804204,0.791695 kka2_1:8_T130R,kka2_1:8_130,Kka2,kka2_1:8,P00552,,YES,130,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.392,-3.981,1.589,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.100394,0.00804204,0.791695 kka2_1:8_T130V,kka2_1:8_130,Kka2,kka2_1:8,P00552,,YES,130,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.392,-3.647,1.255,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.100394,0.00804204,0.775232 kka2_1:8_T130V,kka2_1:8_130,Kka2,kka2_1:8,P00552,,YES,130,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.392,-3.647,1.255,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.100394,0.00804204,0.775232 kka2_1:8_T130Y,kka2_1:8_130,Kka2,kka2_1:8,P00552,,YES,130,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.392,-4.42,2.028,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.100394,0.00804204,0.842567 kka2_1:8_T130Y,kka2_1:8_130,Kka2,kka2_1:8,P00552,,YES,130,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.392,-4.42,2.028,,0.561,G,A,0.22,0.77,2.675,,92.05,HPO,-1.62633,0.100394,0.00804204,0.842567 kka2_1:8_T146E,kka2_1:8_146,Kka2,kka2_1:8,P00552,,YES,146,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.978,-2.468,-0.51,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.100394,0.00606474,0.907272 kka2_1:8_T146E,kka2_1:8_146,Kka2,kka2_1:8,P00552,,YES,146,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-2.978,-2.468,-0.51,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.100394,0.00606474,0.907272 kka2_1:8_T146G,kka2_1:8_146,Kka2,kka2_1:8,P00552,,YES,146,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.978,-3.466,0.488,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.100394,0.00606474,0.725878 kka2_1:8_T146G,kka2_1:8_146,Kka2,kka2_1:8,P00552,,YES,146,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.978,-3.466,0.488,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.100394,0.00606474,0.725878 kka2_1:8_T146H,kka2_1:8_146,Kka2,kka2_1:8,P00552,,YES,146,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.978,-4.762,1.784,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.100394,0.00606474,0.742487 kka2_1:8_T146H,kka2_1:8_146,Kka2,kka2_1:8,P00552,,YES,146,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.978,-4.762,1.784,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.100394,0.00606474,0.742487 kka2_1:8_T146L,kka2_1:8_146,Kka2,kka2_1:8,P00552,,YES,146,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.978,-2.714,-0.264,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.100394,0.00606474,0.845861 kka2_1:8_T146L,kka2_1:8_146,Kka2,kka2_1:8,P00552,,YES,146,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.978,-2.714,-0.264,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.100394,0.00606474,0.845861 kka2_1:8_T146V,kka2_1:8_146,Kka2,kka2_1:8,P00552,,YES,146,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.978,-2.951,-0.027,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.100394,0.00606474,0.817302 kka2_1:8_T146V,kka2_1:8_146,Kka2,kka2_1:8,P00552,,YES,146,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.978,-2.951,-0.027,,0.281,H,A,0.22,0.78,2.081,,92.05,BPB,-1.96833,0.100394,0.00606474,0.817302 kka2_1:8_T225G,kka2_1:8_225,Kka2,kka2_1:8,P00552,,YES,225,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.393,-3.525,1.132,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.100394,0.0113598,0.449114 kka2_1:8_T225G,kka2_1:8_225,Kka2,kka2_1:8,P00552,,YES,225,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.393,-3.525,1.132,,0.036,H,A,0.22,-1.22,1.838,,63.64,HPB,-1.58733,0.100394,0.0113598,0.449114 kka2_1:8_T28H,kka2_1:8_28,Kka2,kka2_1:8,P00552,,YES,28,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.883,-3.548,1.665,,0.353,S,B,0.22,2.02,18.114,18.114,63.64,PPH,-1.74467,0.100394,0.00743084,0.662268 kka2_1:8_T28H,kka2_1:8_28,Kka2,kka2_1:8,P00552,,YES,28,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.883,-3.548,1.665,,0.353,S,B,0.22,2.02,18.114,18.114,63.64,PPH,-1.74467,0.100394,0.00743084,0.662268 kka2_1:8_T28L,kka2_1:8_28,Kka2,kka2_1:8,P00552,,YES,28,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.883,-2.972,1.089,,0.353,S,B,0.22,2.02,18.114,18.114,63.64,PPH,-1.74467,0.100394,0.00743084,0.696548 kka2_1:8_T28L,kka2_1:8_28,Kka2,kka2_1:8,P00552,,YES,28,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.883,-2.972,1.089,,0.353,S,B,0.22,2.02,18.114,18.114,63.64,PPH,-1.74467,0.100394,0.00743084,0.696548 kka2_1:8_T28P,kka2_1:8_28,Kka2,kka2_1:8,P00552,,YES,28,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.883,-3.202,1.319,,0.353,S,B,0.22,2.02,18.114,18.114,63.64,PPH,-1.74467,0.100394,0.00743084,0.633393 kka2_1:8_T28P,kka2_1:8_28,Kka2,kka2_1:8,P00552,,YES,28,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.883,-3.202,1.319,,0.353,S,B,0.22,2.02,18.114,18.114,63.64,PPH,-1.74467,0.100394,0.00743084,0.633393 kka2_1:8_T28V,kka2_1:8_28,Kka2,kka2_1:8,P00552,,YES,28,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.883,-2.663,0.78,,0.353,S,B,0.22,2.02,18.114,18.114,63.64,PPH,-1.74467,0.100394,0.00743084,0.71656 kka2_1:8_T28V,kka2_1:8_28,Kka2,kka2_1:8,P00552,,YES,28,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.883,-2.663,0.78,,0.353,S,B,0.22,2.02,18.114,18.114,63.64,PPH,-1.74467,0.100394,0.00743084,0.71656 kka2_1:8_T51G,kka2_1:8_51,Kka2,kka2_1:8,P00552,,YES,51,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.199,-2.948,0.749,,0.05,E,B,0.82,-0.05,5.399,,63.64,BPA,-1.76767,0.100394,0.00628861,0.51914 kka2_1:8_T51G,kka2_1:8_51,Kka2,kka2_1:8,P00552,,YES,51,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.199,-2.948,0.749,,0.05,E,B,0.82,-0.05,5.399,,63.64,BPA,-1.76767,0.100394,0.00628861,0.51914 kka2_1:8_T51L,kka2_1:8_51,Kka2,kka2_1:8,P00552,,YES,51,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.199,-2.881,0.682,,0.05,E,B,0.82,-0.05,5.399,,63.64,BPA,-1.76767,0.100394,0.00628861,0.5288 kka2_1:8_T51L,kka2_1:8_51,Kka2,kka2_1:8,P00552,,YES,51,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-2.199,-2.881,0.682,,0.05,E,B,0.82,-0.05,5.399,,63.64,BPA,-1.76767,0.100394,0.00628861,0.5288 kka2_1:8_T51P,kka2_1:8_51,Kka2,kka2_1:8,P00552,,YES,51,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.199,-4.078,1.879,,0.05,E,B,0.82,-0.05,5.399,,63.64,BPA,-1.76767,0.100394,0.00628861,0.440268 kka2_1:8_T51P,kka2_1:8_51,Kka2,kka2_1:8,P00552,,YES,51,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-2.199,-4.078,1.879,,0.05,E,B,0.82,-0.05,5.399,,63.64,BPA,-1.76767,0.100394,0.00628861,0.440268 kka2_1:8_T51R,kka2_1:8_51,Kka2,kka2_1:8,P00552,,YES,51,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.199,-3.007,0.808,,0.05,E,B,0.82,-0.05,5.399,,63.64,BPA,-1.76767,0.100394,0.00628861,0.51403 kka2_1:8_T51R,kka2_1:8_51,Kka2,kka2_1:8,P00552,,YES,51,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.199,-3.007,0.808,,0.05,E,B,0.82,-0.05,5.399,,63.64,BPA,-1.76767,0.100394,0.00628861,0.51403 kka2_1:8_T51V,kka2_1:8_51,Kka2,kka2_1:8,P00552,,YES,51,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.199,-2.337,0.138,,0.05,E,B,0.82,-0.05,5.399,,63.64,BPA,-1.76767,0.100394,0.00628861,0.611841 kka2_1:8_T51V,kka2_1:8_51,Kka2,kka2_1:8,P00552,,YES,51,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.199,-2.337,0.138,,0.05,E,B,0.82,-0.05,5.399,,63.64,BPA,-1.76767,0.100394,0.00628861,0.611841 kka2_1:8_T51W,kka2_1:8_51,Kka2,kka2_1:8,P00552,,YES,51,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.199,-5.512,3.313,,0.05,E,B,0.82,-0.05,5.399,,63.64,BPA,-1.76767,0.100394,0.00628861,0.532511 kka2_1:8_T51W,kka2_1:8_51,Kka2,kka2_1:8,P00552,,YES,51,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.199,-5.512,3.313,,0.05,E,B,0.82,-0.05,5.399,,63.64,BPA,-1.76767,0.100394,0.00628861,0.532511 kka2_1:8_T72C,kka2_1:8_72,Kka2,kka2_1:8,P00552,,YES,72,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.38,-5.141,2.761,,0.784,H,A,0.22,0.29,3.603,,65.53,HPP,-2.238,0.100394,0.00750756,0.776045 kka2_1:8_T72C,kka2_1:8_72,Kka2,kka2_1:8,P00552,,YES,72,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-2.38,-5.141,2.761,,0.784,H,A,0.22,0.29,3.603,,65.53,HPP,-2.238,0.100394,0.00750756,0.776045 kka2_1:8_T72G,kka2_1:8_72,Kka2,kka2_1:8,P00552,,YES,72,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.38,-2.12,-0.26,,0.784,H,A,0.22,0.29,3.603,,65.53,HPP,-2.238,0.100394,0.00750756,0.854791 kka2_1:8_T72G,kka2_1:8_72,Kka2,kka2_1:8,P00552,,YES,72,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.38,-2.12,-0.26,,0.784,H,A,0.22,0.29,3.603,,65.53,HPP,-2.238,0.100394,0.00750756,0.854791 kka2_1:8_T72R,kka2_1:8_72,Kka2,kka2_1:8,P00552,,YES,72,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.38,-2.467,0.087,,0.784,H,A,0.22,0.29,3.603,,65.53,HPP,-2.238,0.100394,0.00750756,0.816216 kka2_1:8_T72R,kka2_1:8_72,Kka2,kka2_1:8,P00552,,YES,72,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-2.38,-2.467,0.087,,0.784,H,A,0.22,0.29,3.603,,65.53,HPP,-2.238,0.100394,0.00750756,0.816216 kka2_1:8_T72S,kka2_1:8_72,Kka2,kka2_1:8,P00552,,YES,72,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.38,-2.339,-0.041,,0.784,H,A,0.22,0.29,3.603,,65.53,HPP,-2.238,0.100394,0.00750756,0.840984 kka2_1:8_T72S,kka2_1:8_72,Kka2,kka2_1:8,P00552,,YES,72,T,S,TS,Polar,Polar,5.6,5.68,0.08,58,119,105,-14,116.1,89,-27.1,-2.38,-2.339,-0.041,,0.784,H,A,0.22,0.29,3.603,,65.53,HPP,-2.238,0.100394,0.00750756,0.840984 kka2_1:8_T85D,kka2_1:8_85,Kka2,kka2_1:8,P00552,,YES,85,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.165,-2.694,0.529,,0.576,E,B,0.22,1.39,22.154,22.154,71.59,HPA,-2.10133,0.100394,0.00634493,0.784259 kka2_1:8_T85D,kka2_1:8_85,Kka2,kka2_1:8,P00552,,YES,85,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-2.165,-2.694,0.529,,0.576,E,B,0.22,1.39,22.154,22.154,71.59,HPA,-2.10133,0.100394,0.00634493,0.784259 kka2_1:8_T85F,kka2_1:8_85,Kka2,kka2_1:8,P00552,,YES,85,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.165,-3.388,1.223,,0.576,E,B,0.22,1.39,22.154,22.154,71.59,HPA,-2.10133,0.100394,0.00634493,0.790954 kka2_1:8_T85F,kka2_1:8_85,Kka2,kka2_1:8,P00552,,YES,85,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-2.165,-3.388,1.223,,0.576,E,B,0.22,1.39,22.154,22.154,71.59,HPA,-2.10133,0.100394,0.00634493,0.790954 kka2_1:8_T85G,kka2_1:8_85,Kka2,kka2_1:8,P00552,,YES,85,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.165,-3.601,1.436,,0.576,E,B,0.22,1.39,22.154,22.154,71.59,HPA,-2.10133,0.100394,0.00634493,0.777177 kka2_1:8_T85G,kka2_1:8_85,Kka2,kka2_1:8,P00552,,YES,85,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-2.165,-3.601,1.436,,0.576,E,B,0.22,1.39,22.154,22.154,71.59,HPA,-2.10133,0.100394,0.00634493,0.777177 kka2_1:8_T85H,kka2_1:8_85,Kka2,kka2_1:8,P00552,,YES,85,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.165,-3.24,1.075,,0.576,E,B,0.22,1.39,22.154,22.154,71.59,HPA,-2.10133,0.100394,0.00634493,0.788189 kka2_1:8_T85H,kka2_1:8_85,Kka2,kka2_1:8,P00552,,YES,85,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-2.165,-3.24,1.075,,0.576,E,B,0.22,1.39,22.154,22.154,71.59,HPA,-2.10133,0.100394,0.00634493,0.788189 kka2_1:8_T85K,kka2_1:8_85,Kka2,kka2_1:8,P00552,,YES,85,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.165,-3.032,0.867,,0.576,E,B,0.22,1.39,22.154,22.154,71.59,HPA,-2.10133,0.100394,0.00634493,0.801917 kka2_1:8_T85K,kka2_1:8_85,Kka2,kka2_1:8,P00552,,YES,85,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-2.165,-3.032,0.867,,0.576,E,B,0.22,1.39,22.154,22.154,71.59,HPA,-2.10133,0.100394,0.00634493,0.801917 kka2_1:8_T85Q,kka2_1:8_85,Kka2,kka2_1:8,P00552,,YES,85,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.165,-2.53,0.365,,0.576,E,B,0.22,1.39,22.154,22.154,71.59,HPA,-2.10133,0.100394,0.00634493,0.823352 kka2_1:8_T85Q,kka2_1:8_85,Kka2,kka2_1:8,P00552,,YES,85,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-2.165,-2.53,0.365,,0.576,E,B,0.22,1.39,22.154,22.154,71.59,HPA,-2.10133,0.100394,0.00634493,0.823352 kka2_1:8_T85V,kka2_1:8_85,Kka2,kka2_1:8,P00552,,YES,85,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.165,-2.678,0.513,,0.576,E,B,0.22,1.39,22.154,22.154,71.59,HPA,-2.10133,0.100394,0.00634493,0.766206 kka2_1:8_T85V,kka2_1:8_85,Kka2,kka2_1:8,P00552,,YES,85,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-2.165,-2.678,0.513,,0.576,E,B,0.22,1.39,22.154,22.154,71.59,HPA,-2.10133,0.100394,0.00634493,0.766206 kka2_1:8_T85W,kka2_1:8_85,Kka2,kka2_1:8,P00552,,YES,85,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.165,-5.494,3.329,,0.576,E,B,0.22,1.39,22.154,22.154,71.59,HPA,-2.10133,0.100394,0.00634493,0.778116 kka2_1:8_T85W,kka2_1:8_85,Kka2,kka2_1:8,P00552,,YES,85,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-2.165,-5.494,3.329,,0.576,E,B,0.22,1.39,22.154,22.154,71.59,HPA,-2.10133,0.100394,0.00634493,0.778116 kka2_1:8_T85Y,kka2_1:8_85,Kka2,kka2_1:8,P00552,,YES,85,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.165,-4.263,2.098,,0.576,E,B,0.22,1.39,22.154,22.154,71.59,HPA,-2.10133,0.100394,0.00634493,0.798422 kka2_1:8_T85Y,kka2_1:8_85,Kka2,kka2_1:8,P00552,,YES,85,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-2.165,-4.263,2.098,,0.576,E,B,0.22,1.39,22.154,22.154,71.59,HPA,-2.10133,0.100394,0.00634493,0.798422 kka2_1:8_V113F,kka2_1:8_113,Kka2,kka2_1:8,P00552,,YES,113,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.233,-3.907,2.674,,0.008,H,A,1.48,-1.17,1.254,,52.27,BHP,-2.08367,0.100394,0.00650191,0.374941 kka2_1:8_V113F,kka2_1:8_113,Kka2,kka2_1:8,P00552,,YES,113,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.233,-3.907,2.674,,0.008,H,A,1.48,-1.17,1.254,,52.27,BHP,-2.08367,0.100394,0.00650191,0.374941 kka2_1:8_V113S,kka2_1:8_113,Kka2,kka2_1:8,P00552,,YES,113,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.233,-3.696,2.463,,0.008,H,A,1.48,-1.17,1.254,,52.27,BHP,-2.08367,0.100394,0.00650191,0.436786 kka2_1:8_V113S,kka2_1:8_113,Kka2,kka2_1:8,P00552,,YES,113,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.233,-3.696,2.463,,0.008,H,A,1.48,-1.17,1.254,,52.27,BHP,-2.08367,0.100394,0.00650191,0.436786 kka2_1:8_V153T,kka2_1:8_153,Kka2,kka2_1:8,P00552,,YES,153,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.092,-3.365,2.273,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.100394,0.00501119,0.521741 kka2_1:8_V153T,kka2_1:8_153,Kka2,kka2_1:8,P00552,,YES,153,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.092,-3.365,2.273,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.100394,0.00501119,0.521741 kka2_1:8_V153Y,kka2_1:8_153,Kka2,kka2_1:8,P00552,,YES,153,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.092,-4.06,2.968,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.100394,0.00501119,0.45802 kka2_1:8_V153Y,kka2_1:8_153,Kka2,kka2_1:8,P00552,,YES,153,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.092,-4.06,2.968,,0.158,.,B,0.44,1.35,0.916,,50.38,HHA,-1.163,0.100394,0.00501119,0.45802 kka2_1:8_V16C,kka2_1:8_16,Kka2,kka2_1:8,P00552,,YES,16,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-3.087,-3.613,0.526,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.100394,0.00694011,0.841825 kka2_1:8_V16C,kka2_1:8_16,Kka2,kka2_1:8,P00552,,YES,16,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-3.087,-3.613,0.526,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.100394,0.00694011,0.841825 kka2_1:8_V16K,kka2_1:8_16,Kka2,kka2_1:8,P00552,,YES,16,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-3.087,-2.781,-0.306,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.100394,0.00694011,0.903515 kka2_1:8_V16K,kka2_1:8_16,Kka2,kka2_1:8,P00552,,YES,16,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-3.087,-2.781,-0.306,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.100394,0.00694011,0.903515 kka2_1:8_V16N,kka2_1:8_16,Kka2,kka2_1:8,P00552,,YES,16,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-3.087,-3.138,0.051,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.100394,0.00694011,0.860781 kka2_1:8_V16N,kka2_1:8_16,Kka2,kka2_1:8,P00552,,YES,16,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-3.087,-3.138,0.051,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.100394,0.00694011,0.860781 kka2_1:8_V16R,kka2_1:8_16,Kka2,kka2_1:8,P00552,,YES,16,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-3.087,-1.961,-1.126,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.100394,0.00694011,0.963996 kka2_1:8_V16R,kka2_1:8_16,Kka2,kka2_1:8,P00552,,YES,16,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-3.087,-1.961,-1.126,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.100394,0.00694011,0.963996 kka2_1:8_V16T,kka2_1:8_16,Kka2,kka2_1:8,P00552,,YES,16,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-3.087,-3.05,-0.037,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.100394,0.00694011,0.857264 kka2_1:8_V16T,kka2_1:8_16,Kka2,kka2_1:8,P00552,,YES,16,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-3.087,-3.05,-0.037,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.100394,0.00694011,0.857264 kka2_1:8_V16Y,kka2_1:8_16,Kka2,kka2_1:8,P00552,,YES,16,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-3.087,-4.365,1.278,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.100394,0.00694011,0.861802 kka2_1:8_V16Y,kka2_1:8_16,Kka2,kka2_1:8,P00552,,YES,16,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-3.087,-4.365,1.278,,0.742,T,A,0.44,0.34,0.569,,71.59,HHA,-2.211,0.100394,0.00694011,0.861802 kka2_1:8_V214Q,kka2_1:8_214,Kka2,kka2_1:8,P00552,,YES,214,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.261,-4.289,3.028,,0.117,E,B,1.48,-0.31,1.859,,64.39,OHH,-0.941667,0.100394,0.00692782,0.441118 kka2_1:8_V214Q,kka2_1:8_214,Kka2,kka2_1:8,P00552,,YES,214,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.261,-4.289,3.028,,0.117,E,B,1.48,-0.31,1.859,,64.39,OHH,-0.941667,0.100394,0.00692782,0.441118 kka2_1:8_V242P,kka2_1:8_242,Kka2,kka2_1:8,P00552,,YES,242,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-2.687,-4.019,1.332,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.100394,0.0102575,0.842752 kka2_1:8_V242P,kka2_1:8_242,Kka2,kka2_1:8,P00552,,YES,242,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-2.687,-4.019,1.332,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.100394,0.0102575,0.842752 kka2_1:8_V242Y,kka2_1:8_242,Kka2,kka2_1:8,P00552,,YES,242,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-2.687,-4.381,1.694,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.100394,0.0102575,0.972014 kka2_1:8_V242Y,kka2_1:8_242,Kka2,kka2_1:8,P00552,,YES,242,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-2.687,-4.381,1.694,,0.75,H,A,0.44,-0.37,,,71.59,HHH,-2.16533,0.100394,0.0102575,0.972014 kka2_1:8_V36K,kka2_1:8_36,Kka2,kka2_1:8,P00552,,YES,36,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-0.898,-3.793,2.895,,0.292,E,B,1.48,0.21,0.938,,52.27,HHH,-1.484,0.100394,0.00245633,0.416854 kka2_1:8_V36K,kka2_1:8_36,Kka2,kka2_1:8,P00552,,YES,36,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-0.898,-3.793,2.895,,0.292,E,B,1.48,0.21,0.938,,52.27,HHH,-1.484,0.100394,0.00245633,0.416854 kka2_1:8_V46H,kka2_1:8_46,Kka2,kka2_1:8,P00552,,YES,46,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-2.62,-3.614,0.994,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.100394,0.00631301,0.645577 kka2_1:8_V46H,kka2_1:8_46,Kka2,kka2_1:8,P00552,,YES,46,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-2.62,-3.614,0.994,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.100394,0.00631301,0.645577 kka2_1:8_V46Y,kka2_1:8_46,Kka2,kka2_1:8,P00552,,YES,46,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-2.62,-4.392,1.772,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.100394,0.00631301,0.626772 kka2_1:8_V46Y,kka2_1:8_46,Kka2,kka2_1:8,P00552,,YES,46,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-2.62,-4.392,1.772,,0.192,.,B,0.44,-1.12,0.936,,92.05,OHH,-1.88633,0.100394,0.00631301,0.626772 kka2_1:8_V75Q,kka2_1:8_75,Kka2,kka2_1:8,P00552,,YES,75,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-2.06,-2.734,0.674,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.100394,0.00693733,0.677113 kka2_1:8_V75Q,kka2_1:8_75,Kka2,kka2_1:8,P00552,,YES,75,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-2.06,-2.734,0.674,,0.042,.,B,0.44,-0.2,2.496,,71.59,OHO,-1.563,0.100394,0.00693733,0.677113 kka2_1:8_V83H,kka2_1:8_83,Kka2,kka2_1:8,P00552,,YES,83,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-2.567,-2.84,0.273,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.100394,0.00650486,0.828813 kka2_1:8_V83H,kka2_1:8_83,Kka2,kka2_1:8,P00552,,YES,83,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-2.567,-2.84,0.273,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.100394,0.00650486,0.828813 kka2_1:8_V83I,kka2_1:8_83,Kka2,kka2_1:8,P00552,,YES,83,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-2.567,-3.777,1.21,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.100394,0.00650486,0.705317 kka2_1:8_V83I,kka2_1:8_83,Kka2,kka2_1:8,P00552,,YES,83,V,I,VI,Hydrophobic,Hydrophobic,5.60847,6.02,0.411535,29,117,131,14,140,166.7,26.7,-2.567,-3.777,1.21,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.100394,0.00650486,0.705317 kka2_1:8_V83N,kka2_1:8_83,Kka2,kka2_1:8,P00552,,YES,83,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-2.567,-3.217,0.65,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.100394,0.00650486,0.774893 kka2_1:8_V83N,kka2_1:8_83,Kka2,kka2_1:8,P00552,,YES,83,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-2.567,-3.217,0.65,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.100394,0.00650486,0.774893 kka2_1:8_V83R,kka2_1:8_83,Kka2,kka2_1:8,P00552,,YES,83,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-2.567,-2.854,0.287,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.100394,0.00650486,0.827141 kka2_1:8_V83R,kka2_1:8_83,Kka2,kka2_1:8,P00552,,YES,83,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-2.567,-2.854,0.287,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.100394,0.00650486,0.827141 kka2_1:8_V83S,kka2_1:8_83,Kka2,kka2_1:8,P00552,,YES,83,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-2.567,-2.85,0.283,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.100394,0.00650486,0.802617 kka2_1:8_V83S,kka2_1:8_83,Kka2,kka2_1:8,P00552,,YES,83,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-2.567,-2.85,0.283,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.100394,0.00650486,0.802617 kka2_1:8_V83T,kka2_1:8_83,Kka2,kka2_1:8,P00552,,YES,83,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-2.567,-2.28,-0.287,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.100394,0.00650486,0.893546 kka2_1:8_V83T,kka2_1:8_83,Kka2,kka2_1:8,P00552,,YES,83,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-2.567,-2.28,-0.287,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.100394,0.00650486,0.893546 kka2_1:8_V83W,kka2_1:8_83,Kka2,kka2_1:8,P00552,,YES,83,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-2.567,-5.342,2.775,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.100394,0.00650486,0.773241 kka2_1:8_V83W,kka2_1:8_83,Kka2,kka2_1:8,P00552,,YES,83,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-2.567,-5.342,2.775,,0.358,E,B,0.44,0.53,2.081,,71.59,AHH,-2.264,0.100394,0.00650486,0.773241 kka2_1:8_V84C,kka2_1:8_84,Kka2,kka2_1:8,P00552,,YES,84,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-2.279,-5.009,2.73,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.100394,0.00724019,0.846613 kka2_1:8_V84C,kka2_1:8_84,Kka2,kka2_1:8,P00552,,YES,84,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-2.279,-5.009,2.73,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.100394,0.00724019,0.846613 kka2_1:8_V84D,kka2_1:8_84,Kka2,kka2_1:8,P00552,,YES,84,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-2.279,-2.613,0.334,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.100394,0.00724019,0.739967 kka2_1:8_V84D,kka2_1:8_84,Kka2,kka2_1:8,P00552,,YES,84,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-2.279,-2.613,0.334,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.100394,0.00724019,0.739967 kka2_1:8_V84E,kka2_1:8_84,Kka2,kka2_1:8,P00552,,YES,84,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-2.279,-2.088,-0.191,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.100394,0.00724019,0.846607 kka2_1:8_V84E,kka2_1:8_84,Kka2,kka2_1:8,P00552,,YES,84,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-2.279,-2.088,-0.191,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.100394,0.00724019,0.846607 kka2_1:8_V84N,kka2_1:8_84,Kka2,kka2_1:8,P00552,,YES,84,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-2.279,-3.883,1.604,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.100394,0.00724019,0.713334 kka2_1:8_V84N,kka2_1:8_84,Kka2,kka2_1:8,P00552,,YES,84,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-2.279,-3.883,1.604,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.100394,0.00724019,0.713334 kka2_1:8_V84Q,kka2_1:8_84,Kka2,kka2_1:8,P00552,,YES,84,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-2.279,-3.218,0.939,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.100394,0.00724019,0.750665 kka2_1:8_V84Q,kka2_1:8_84,Kka2,kka2_1:8,P00552,,YES,84,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-2.279,-3.218,0.939,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.100394,0.00724019,0.750665 kka2_1:8_V84R,kka2_1:8_84,Kka2,kka2_1:8,P00552,,YES,84,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-2.279,-3.996,1.717,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.100394,0.00724019,0.707715 kka2_1:8_V84R,kka2_1:8_84,Kka2,kka2_1:8,P00552,,YES,84,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-2.279,-3.996,1.717,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.100394,0.00724019,0.707715 kka2_1:8_V84T,kka2_1:8_84,Kka2,kka2_1:8,P00552,,YES,84,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-2.279,-2.154,-0.125,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.100394,0.00724019,0.866453 kka2_1:8_V84T,kka2_1:8_84,Kka2,kka2_1:8,P00552,,YES,84,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-2.279,-2.154,-0.125,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.100394,0.00724019,0.866453 kka2_1:8_V84W,kka2_1:8_84,Kka2,kka2_1:8,P00552,,YES,84,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-2.279,-5.522,3.243,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.100394,0.00724019,0.747401 kka2_1:8_V84W,kka2_1:8_84,Kka2,kka2_1:8,P00552,,YES,84,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-2.279,-5.522,3.243,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.100394,0.00724019,0.747401 kka2_1:8_V84Y,kka2_1:8_84,Kka2,kka2_1:8,P00552,,YES,84,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-2.279,-4.308,2.029,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.100394,0.00724019,0.71605 kka2_1:8_V84Y,kka2_1:8_84,Kka2,kka2_1:8,P00552,,YES,84,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-2.279,-4.308,2.029,,0.258,E,B,0.44,1.03,2.081,,71.59,HHP,-2.337,0.100394,0.00724019,0.71605 kka2_1:8_V97S,kka2_1:8_97,Kka2,kka2_1:8,P00552,,YES,97,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.453,-3.709,2.256,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.100394,0.00737869,0.484908 kka2_1:8_V97S,kka2_1:8_97,Kka2,kka2_1:8,P00552,,YES,97,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.453,-3.709,2.256,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.100394,0.00737869,0.484908 kka2_1:8_V97T,kka2_1:8_97,Kka2,kka2_1:8,P00552,,YES,97,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.453,-3.491,2.038,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.100394,0.00737869,0.497467 kka2_1:8_V97T,kka2_1:8_97,Kka2,kka2_1:8,P00552,,YES,97,V,T,VT,Hydrophobic,Polar,5.60847,5.6,-0.00846535,69,117,119,2,140,116.1,-23.9,-1.453,-3.491,2.038,,0.083,.,B,0.44,-0.83,1.519,,53.03,AHO,-1.85067,0.100394,0.00737869,0.497467 kka2_1:8_W15A,kka2_1:8_15,Kka2,kka2_1:8,P00552,,YES,15,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-1.392,-3.416,2.024,,0.01,G,A,1.51,0.15,0.827,,52.27,HHH,-2.10533,0.100394,0.00585505,0.514486 kka2_1:8_W15A,kka2_1:8_15,Kka2,kka2_1:8,P00552,,YES,15,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-1.392,-3.416,2.024,,0.01,G,A,1.51,0.15,0.827,,52.27,HHH,-2.10533,0.100394,0.00585505,0.514486 kka2_1:8_W15E,kka2_1:8_15,Kka2,kka2_1:8,P00552,,YES,15,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-1.392,-4.005,2.613,,0.01,G,A,1.51,0.15,0.827,,52.27,HHH,-2.10533,0.100394,0.00585505,0.427103 kka2_1:8_W15E,kka2_1:8_15,Kka2,kka2_1:8,P00552,,YES,15,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-1.392,-4.005,2.613,,0.01,G,A,1.51,0.15,0.827,,52.27,HHH,-2.10533,0.100394,0.00585505,0.427103 kka2_1:8_W15H,kka2_1:8_15,Kka2,kka2_1:8,P00552,,YES,15,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-1.392,-4.848,3.456,,0.01,G,A,1.51,0.15,0.827,,52.27,HHH,-2.10533,0.100394,0.00585505,0.461067 kka2_1:8_W15H,kka2_1:8_15,Kka2,kka2_1:8,P00552,,YES,15,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-1.392,-4.848,3.456,,0.01,G,A,1.51,0.15,0.827,,52.27,HHH,-2.10533,0.100394,0.00585505,0.461067 kka2_1:8_W15I,kka2_1:8_15,Kka2,kka2_1:8,P00552,,YES,15,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-1.392,-2.748,1.356,,0.01,G,A,1.51,0.15,0.827,,52.27,HHH,-2.10533,0.100394,0.00585505,0.507075 kka2_1:8_W15I,kka2_1:8_15,Kka2,kka2_1:8,P00552,,YES,15,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-1.392,-2.748,1.356,,0.01,G,A,1.51,0.15,0.827,,52.27,HHH,-2.10533,0.100394,0.00585505,0.507075 kka2_1:8_W236V,kka2_1:8_236,Kka2,kka2_1:8,P00552,,YES,236,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-1.363,-3.56,2.197,,0.303,H,A,1.51,-0.76,1.87,,48.48,AHH,-1.81267,0.100394,0.0088796,0.480637 kka2_1:8_W236V,kka2_1:8_236,Kka2,kka2_1:8,P00552,,YES,236,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-1.363,-3.56,2.197,,0.303,H,A,1.51,-0.76,1.87,,48.48,AHH,-1.81267,0.100394,0.0088796,0.480637 kka2_1:8_W24K,kka2_1:8_24,Kka2,kka2_1:8,P00552,,YES,24,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-1.779,-4.012,2.233,,0.477,E,B,1.51,-0.21,2.503,,56.06,AHH,-2.24467,0.100394,0.00631564,0.438112 kka2_1:8_W24K,kka2_1:8_24,Kka2,kka2_1:8,P00552,,YES,24,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-1.779,-4.012,2.233,,0.477,E,B,1.51,-0.21,2.503,,56.06,AHH,-2.24467,0.100394,0.00631564,0.438112 kka2_1:8_W69A,kka2_1:8_69,Kka2,kka2_1:8,P00552,,YES,69,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-0.859,-3.554,2.695,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.100394,0.0012874,0.451504 kka2_1:8_W69A,kka2_1:8_69,Kka2,kka2_1:8,P00552,,YES,69,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-0.859,-3.554,2.695,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.100394,0.0012874,0.451504 kka2_1:8_W69E,kka2_1:8_69,Kka2,kka2_1:8,P00552,,YES,69,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-0.859,-3.916,3.057,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.100394,0.0012874,0.403198 kka2_1:8_W69E,kka2_1:8_69,Kka2,kka2_1:8,P00552,,YES,69,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-0.859,-3.916,3.057,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.100394,0.0012874,0.403198 kka2_1:8_W69I,kka2_1:8_69,Kka2,kka2_1:8,P00552,,YES,69,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-0.859,-4.006,3.147,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.100394,0.0012874,0.387656 kka2_1:8_W69I,kka2_1:8_69,Kka2,kka2_1:8,P00552,,YES,69,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-0.859,-4.006,3.147,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.100394,0.0012874,0.387656 kka2_1:8_W69K,kka2_1:8_69,Kka2,kka2_1:8,P00552,,YES,69,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-0.859,-3.933,3.074,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.100394,0.0012874,0.402039 kka2_1:8_W69K,kka2_1:8_69,Kka2,kka2_1:8,P00552,,YES,69,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-0.859,-3.933,3.074,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.100394,0.0012874,0.402039 kka2_1:8_W69S,kka2_1:8_69,Kka2,kka2_1:8,P00552,,YES,69,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-0.859,-3.862,3.003,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.100394,0.0012874,0.463082 kka2_1:8_W69S,kka2_1:8_69,Kka2,kka2_1:8,P00552,,YES,69,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,-0.859,-3.862,3.003,,0.164,H,A,0.47,0.15,1.854,,38.64,PHH,-1.49967,0.100394,0.0012874,0.463082 kka2_1:8_W91K,kka2_1:8_91,Kka2,kka2_1:8,P00552,,YES,91,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-1.178,-3.72,2.542,,0.077,E,B,1.51,0.27,2.51,,48.48,AHH,-1.51,0.100394,0.00358653,0.443812 kka2_1:8_W91K,kka2_1:8_91,Kka2,kka2_1:8,P00552,,YES,91,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-1.178,-3.72,2.542,,0.077,E,B,1.51,0.27,2.51,,48.48,AHH,-1.51,0.100394,0.00358653,0.443812 kka2_1:8_W91T,kka2_1:8_91,Kka2,kka2_1:8,P00552,,YES,91,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-1.178,-3.718,2.54,,0.077,E,B,1.51,0.27,2.51,,48.48,AHH,-1.51,0.100394,0.00358653,0.493467 kka2_1:8_W91T,kka2_1:8_91,Kka2,kka2_1:8,P00552,,YES,91,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-1.178,-3.718,2.54,,0.077,E,B,1.51,0.27,2.51,,48.48,AHH,-1.51,0.100394,0.00358653,0.493467 kka2_1:8_Y218A,kka2_1:8_218,Kka2,kka2_1:8,P00552,,YES,218,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-1.438,-2.767,1.329,,0.122,H,A,1.25,-0.69,2.923,,56.06,BHP,-1.17533,0.100394,0.0126098,0.506811 kka2_1:8_Y218A,kka2_1:8_218,Kka2,kka2_1:8,P00552,,YES,218,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-1.438,-2.767,1.329,,0.122,H,A,1.25,-0.69,2.923,,56.06,BHP,-1.17533,0.100394,0.0126098,0.506811 kka2_1:8_Y218Q,kka2_1:8_218,Kka2,kka2_1:8,P00552,,YES,218,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-1.438,-4.079,2.641,,0.122,H,A,1.25,-0.69,2.923,,56.06,BHP,-1.17533,0.100394,0.0126098,0.44447 kka2_1:8_Y218Q,kka2_1:8_218,Kka2,kka2_1:8,P00552,,YES,218,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-1.438,-4.079,2.641,,0.122,H,A,1.25,-0.69,2.923,,56.06,BHP,-1.17533,0.100394,0.0126098,0.44447 kka2_1:8_Y22A,kka2_1:8_22,Kka2,kka2_1:8,P00552,,YES,22,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-1.583,-1.97,0.387,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.100394,0.00598977,0.628941 kka2_1:8_Y22A,kka2_1:8_22,Kka2,kka2_1:8,P00552,,YES,22,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-1.583,-1.97,0.387,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.100394,0.00598977,0.628941 kka2_1:8_Y22T,kka2_1:8_22,Kka2,kka2_1:8,P00552,,YES,22,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-1.583,-2.95,1.367,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.100394,0.00598977,0.566546 kka2_1:8_Y22T,kka2_1:8_22,Kka2,kka2_1:8,P00552,,YES,22,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-1.583,-2.95,1.367,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.100394,0.00598977,0.566546 kka2_1:8_Y22V,kka2_1:8_22,Kka2,kka2_1:8,P00552,,YES,22,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-1.583,-3.487,1.904,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.100394,0.00598977,0.486507 kka2_1:8_Y22V,kka2_1:8_22,Kka2,kka2_1:8,P00552,,YES,22,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-1.583,-3.487,1.904,,0.122,.,B,0.21,-0.8,4.666,,65.53,OHA,-1.80333,0.100394,0.00598977,0.486507 Pab1_A141A,Pab1_141,Pab1,Pab1,P04147,,YES,141,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.461,-1.461,,,0.34,H,A,0.52,-0.27,2.15,,79.03,BHH,-1.19433,0.175299,0.00165974,0.832065 Pab1_A141K,Pab1_141,Pab1,Pab1,P04147,,YES,141,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.461,-3.34,1.879,,0.34,H,A,0.52,-0.27,2.15,,79.03,BHH,-1.19433,0.175299,0.00165974,0.808307 Pab1_A141M,Pab1_141,Pab1,Pab1,P04147,,YES,141,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.461,-4.408,2.947,,0.34,H,A,0.52,-0.27,2.15,,79.03,BHH,-1.19433,0.175299,0.00165974,0.79438 Pab1_A141Q,Pab1_141,Pab1,Pab1,P04147,,YES,141,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.461,-3.782,2.321,,0.34,H,A,0.52,-0.27,2.15,,79.03,BHH,-1.19433,0.175299,0.00165974,0.780322 Pab1_A141W,Pab1_141,Pab1,Pab1,P04147,,YES,141,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.461,-5.163,3.702,,0.34,H,A,0.52,-0.27,2.15,,79.03,BHH,-1.19433,0.175299,0.00165974,0.750747 Pab1_A158K,Pab1_158,Pab1,Pab1,P04147,,YES,158,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.154,-3.378,2.224,,,,,,,1.197,,56.33,HHP,-1.40733,0.175299,0.000649733,0.727186 Pab1_A158M,Pab1_158,Pab1,Pab1,P04147,,YES,158,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.154,-4.22,3.066,,,,,,,1.197,,56.33,HHP,-1.40733,0.175299,0.000649733,0.705678 Pab1_A158Q,Pab1_158,Pab1,Pab1,P04147,,YES,158,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.154,-3.82,2.666,,,,,,,1.197,,56.33,HHP,-1.40733,0.175299,0.000649733,0.662439 Pab1_A158W,Pab1_158,Pab1,Pab1,P04147,,YES,158,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.154,-5.193,4.039,,,,,,,1.197,,56.33,HHP,-1.40733,0.175299,0.000649733,0.668271 Pab1_A178A,Pab1_178,Pab1,Pab1,P04147,,YES,178,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.579,-1.579,,,0.019,H,A,0.64,0.64,2.7,,81.63,OHH,-1.61067,0.175299,0.00160192,0.878763 Pab1_A178K,Pab1_178,Pab1,Pab1,P04147,,YES,178,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.579,-3.416,1.837,,0.019,H,A,0.64,0.64,2.7,,81.63,OHH,-1.61067,0.175299,0.00160192,0.862549 Pab1_A178M,Pab1_178,Pab1,Pab1,P04147,,YES,178,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.579,-4.438,2.859,,0.019,H,A,0.64,0.64,2.7,,81.63,OHH,-1.61067,0.175299,0.00160192,0.851148 Pab1_A178W,Pab1_178,Pab1,Pab1,P04147,,YES,178,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.579,-5.332,3.753,,0.019,H,A,0.64,0.64,2.7,,81.63,OHH,-1.61067,0.175299,0.00160192,0.823889 Pab1_A179A,Pab1_179,Pab1,Pab1,P04147,,YES,179,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.013,-1.013,,,0.078,H,A,0.61,0.5,,,,HHB,-1.51233,0.175299,0.000291703,0.849698 Pab1_A179K,Pab1_179,Pab1,Pab1,P04147,,YES,179,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.013,-3.274,2.261,,0.078,H,A,0.61,0.5,,,,HHB,-1.51233,0.175299,0.000291703,0.800234 Pab1_A179M,Pab1_179,Pab1,Pab1,P04147,,YES,179,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.013,-4.297,3.284,,0.078,H,A,0.61,0.5,,,,HHB,-1.51233,0.175299,0.000291703,0.745417 Pab1_A179Q,Pab1_179,Pab1,Pab1,P04147,,YES,179,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.013,-3.716,2.703,,0.078,H,A,0.61,0.5,,,,HHB,-1.51233,0.175299,0.000291703,0.7218 Pab1_A179W,Pab1_179,Pab1,Pab1,P04147,,YES,179,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.013,-5.14,4.127,,0.078,H,A,0.61,0.5,,,,HHB,-1.51233,0.175299,0.000291703,0.705533 Pab1_A182A,Pab1_182,Pab1,Pab1,P04147,,YES,182,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.013,-1.013,,,,H,A,0.17,0.79,,,,AHH,-1.36067,0.175299,0.000289034,0.857098 Pab1_A182K,Pab1_182,Pab1,Pab1,P04147,,YES,182,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.013,-3.274,2.261,,,H,A,0.17,0.79,,,,AHH,-1.36067,0.175299,0.000289034,0.77891 Pab1_A182M,Pab1_182,Pab1,Pab1,P04147,,YES,182,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.013,-4.297,3.284,,,H,A,0.17,0.79,,,,AHH,-1.36067,0.175299,0.000289034,0.730588 Pab1_A182Q,Pab1_182,Pab1,Pab1,P04147,,YES,182,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.013,-3.716,2.703,,,H,A,0.17,0.79,,,,AHH,-1.36067,0.175299,0.000289034,0.703602 Pab1_A182W,Pab1_182,Pab1,Pab1,P04147,,YES,182,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.013,-5.14,4.127,,,H,A,0.17,0.79,,,,AHH,-1.36067,0.175299,0.000289034,0.66771 Pab1_A185A,Pab1_185,Pab1,Pab1,P04147,,YES,185,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.702,-1.702,,,,,,,,1.756,,63.26,AHH,-1.66167,0.175299,0.00144499,0.818588 Pab1_A185K,Pab1_185,Pab1,Pab1,P04147,,YES,185,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.702,-3.314,1.612,,,,,,,1.756,,63.26,AHH,-1.66167,0.175299,0.00144499,0.794546 Pab1_A185M,Pab1_185,Pab1,Pab1,P04147,,YES,185,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.702,-4.562,2.86,,,,,,,1.756,,63.26,AHH,-1.66167,0.175299,0.00144499,0.807204 Pab1_A185Q,Pab1_185,Pab1,Pab1,P04147,,YES,185,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.702,-3.756,2.054,,,,,,,1.756,,63.26,AHH,-1.66167,0.175299,0.00144499,0.776105 Pab1_A185W,Pab1_185,Pab1,Pab1,P04147,,YES,185,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.702,-5.293,3.591,,,,,,,1.756,,63.26,AHH,-1.66167,0.175299,0.00144499,0.752684 Pab1_A199A,Pab1_199,Pab1,Pab1,P04147,,YES,199,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.53,-1.53,,,,,,,,1.479,,80.42,HHO,-1.50467,0.175299,0.00145024,0.810928 Pab1_A199I,Pab1_199,Pab1,Pab1,P04147,,YES,199,A,I,AI,Hydrophobic,Hydrophobic,6,6.02,0.02,94,89,131,42,88.6,166.7,78.1,-1.53,-3.767,2.237,,,,,,,1.479,,80.42,HHO,-1.50467,0.175299,0.00145024,0.746849 Pab1_A199K,Pab1_199,Pab1,Pab1,P04147,,YES,199,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.53,-3.464,1.934,,,,,,,1.479,,80.42,HHO,-1.50467,0.175299,0.00145024,0.748096 Pab1_A199M,Pab1_199,Pab1,Pab1,P04147,,YES,199,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.53,-4.593,3.063,,,,,,,1.479,,80.42,HHO,-1.50467,0.175299,0.00145024,0.800651 Pab1_A199N,Pab1_199,Pab1,Pab1,P04147,,YES,199,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.53,-3.512,1.982,,,,,,,1.479,,80.42,HHO,-1.50467,0.175299,0.00145024,0.760985 Pab1_A199Q,Pab1_199,Pab1,Pab1,P04147,,YES,199,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.53,-3.906,2.376,,,,,,,1.479,,80.42,HHO,-1.50467,0.175299,0.00145024,0.754903 Pab1_A199R,Pab1_199,Pab1,Pab1,P04147,,YES,199,A,R,AR,Hydrophobic,PositiveCharge,6,6.34148,0.341478,112,89,174,85,88.6,173.4,84.8,-1.53,-3.715,2.185,,,,,,,1.479,,80.42,HHO,-1.50467,0.175299,0.00145024,0.730362 Pab1_A199W,Pab1_199,Pab1,Pab1,P04147,,YES,199,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.53,-5.08,3.55,,,,,,,1.479,,80.42,HHO,-1.50467,0.175299,0.00145024,0.748868 Pab1_A199Y,Pab1_199,Pab1,Pab1,P04147,,YES,199,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.53,-4.17,2.64,,,,,,,1.479,,80.42,HHO,-1.50467,0.175299,0.00145024,0.772255 Pab1_D136D,Pab1_136,Pab1,Pab1,P04147,,YES,136,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.602,-1.602,,,,,,,,,,,OAH,-1.42367,0.175299,0.00227029,0.826278 Pab1_D136M,Pab1_136,Pab1,Pab1,P04147,,YES,136,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.602,-4.483,2.881,,,,,,,,,,OAH,-1.42367,0.175299,0.00227029,0.862342 Pab1_D136W,Pab1_136,Pab1,Pab1,P04147,,YES,136,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.602,-5.356,3.754,,,,,,,,,,OAH,-1.42367,0.175299,0.00227029,0.854184 Pab1_D138D,Pab1_138,Pab1,Pab1,P04147,,YES,138,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.128,-1.128,,,0.427,,B,,-0.03,,,,HAP,-1.13967,0.175299,0.000567877,0.797882 Pab1_D138M,Pab1_138,Pab1,Pab1,P04147,,YES,138,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.128,-4.74,3.612,,0.427,,B,,-0.03,,,,HAP,-1.13967,0.175299,0.000567877,0.786706 Pab1_D138W,Pab1_138,Pab1,Pab1,P04147,,YES,138,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.128,-5.358,4.23,,0.427,,B,,-0.03,,,,HAP,-1.13967,0.175299,0.000567877,0.784564 Pab1_D144D,Pab1_144,Pab1,Pab1,P04147,,YES,144,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.189,-1.189,,,0.616,H,A,,0.6,,,,HAP,-1.40567,0.175299,0.00121131,0.833425 Pab1_D144M,Pab1_144,Pab1,Pab1,P04147,,YES,144,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.189,-4.743,3.554,,0.616,H,A,,0.6,,,,HAP,-1.40567,0.175299,0.00121131,0.853758 Pab1_D144W,Pab1_144,Pab1,Pab1,P04147,,YES,144,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.189,-5.361,4.172,,0.616,H,A,,0.6,,,,HAP,-1.40567,0.175299,0.00121131,0.851188 Pab1_D151D,Pab1_151,Pab1,Pab1,P04147,,YES,151,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-2.399,-2.399,,,,,,,,,,,OAH,-1.51767,0.175299,0.00228155,0.822529 Pab1_D151M,Pab1_151,Pab1,Pab1,P04147,,YES,151,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-2.399,-4.619,2.22,,,,,,,,,,OAH,-1.51767,0.175299,0.00228155,0.858044 Pab1_D151W,Pab1_151,Pab1,Pab1,P04147,,YES,151,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-2.399,-5.383,2.984,,,,,,,,,,OAH,-1.51767,0.175299,0.00228155,0.859466 Pab1_D160M,Pab1_160,Pab1,Pab1,P04147,,YES,160,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-0.985,-4.747,3.762,,0.396,B,B,,1.12,,,,PAA,-1.30133,0.175299,0.000311977,0.878903 Pab1_D160W,Pab1_160,Pab1,Pab1,P04147,,YES,160,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-0.985,-5.365,4.38,,0.396,B,B,,1.12,,,,PAA,-1.30133,0.175299,0.000311977,0.876937 Pab1_D184D,Pab1_184,Pab1,Pab1,P04147,,YES,184,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.5,-1.5,,,,,,,,,,,HAH,-1.50133,0.175299,0.0011931,0.828893 Pab1_D184M,Pab1_184,Pab1,Pab1,P04147,,YES,184,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.5,-4.687,3.187,,,,,,,,,,HAH,-1.50133,0.175299,0.0011931,0.865008 Pab1_D184W,Pab1_184,Pab1,Pab1,P04147,,YES,184,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.5,-5.305,3.805,,,,,,,,,,HAH,-1.50133,0.175299,0.0011931,0.854729 Pab1_E161C,Pab1_161,Pab1,Pab1,P04147,,YES,161,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.474,-5.002,3.528,,0.663,T,a,,1.34,,,,AAP,-1.59067,0.175299,0.00276141,0.892812 Pab1_E161F,Pab1_161,Pab1,Pab1,P04147,,YES,161,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.474,-4.22,2.746,,0.663,T,a,,1.34,,,,AAP,-1.59067,0.175299,0.00276141,0.860925 Pab1_E161M,Pab1_161,Pab1,Pab1,P04147,,YES,161,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.474,-4.677,3.203,,0.663,T,a,,1.34,,,,AAP,-1.59067,0.175299,0.00276141,0.864444 Pab1_E161W,Pab1_161,Pab1,Pab1,P04147,,YES,161,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.474,-5.367,3.893,,0.663,T,a,,1.34,,,,AAP,-1.59067,0.175299,0.00276141,0.858446 Pab1_E174C,Pab1_174,Pab1,Pab1,P04147,,YES,174,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.422,-5.144,3.722,,0.578,S,A,,0.38,,,,HAA,-1.65133,0.175299,0.00077863,0.873465 Pab1_E174F,Pab1_174,Pab1,Pab1,P04147,,YES,174,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.422,-4.241,2.819,,0.578,S,A,,0.38,,,,HAA,-1.65133,0.175299,0.00077863,0.844996 Pab1_E174M,Pab1_174,Pab1,Pab1,P04147,,YES,174,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.422,-4.605,3.183,,0.578,S,A,,0.38,,,,HAA,-1.65133,0.175299,0.00077863,0.847185 Pab1_E174W,Pab1_174,Pab1,Pab1,P04147,,YES,174,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.422,-5.305,3.883,,0.578,S,A,,0.38,,,,HAA,-1.65133,0.175299,0.00077863,0.842388 Pab1_E175C,Pab1_175,Pab1,Pab1,P04147,,YES,175,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.055,-4.97,2.915,,,,,,,,,,AAA,-1.82667,0.175299,0.00203137,0.89714 Pab1_E175F,Pab1_175,Pab1,Pab1,P04147,,YES,175,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-2.055,-4.199,2.144,,,,,,,,,,AAA,-1.82667,0.175299,0.00203137,0.866274 Pab1_E175M,Pab1_175,Pab1,Pab1,P04147,,YES,175,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.055,-4.69,2.635,,,,,,,,,,AAA,-1.82667,0.175299,0.00203137,0.8613 Pab1_E175W,Pab1_175,Pab1,Pab1,P04147,,YES,175,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.055,-5.361,3.306,,,,,,,,,,AAA,-1.82667,0.175299,0.00203137,0.857948 Pab1_E176C,Pab1_176,Pab1,Pab1,P04147,,YES,176,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-2.003,-4.909,2.906,,,,,,,,,,AAO,-2.09933,0.175299,0.00264426,0.898502 Pab1_E176E,Pab1_176,Pab1,Pab1,P04147,,YES,176,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-2.003,-2.003,,,,,,,,,,,AAO,-2.09933,0.175299,0.00264426,0.849709 Pab1_E176M,Pab1_176,Pab1,Pab1,P04147,,YES,176,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-2.003,-4.719,2.716,,,,,,,,,,AAO,-2.09933,0.175299,0.00264426,0.862104 Pab1_E176W,Pab1_176,Pab1,Pab1,P04147,,YES,176,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-2.003,-5.393,3.39,,,,,,,,,,AAO,-2.09933,0.175299,0.00264426,0.859062 Pab1_E181C,Pab1_181,Pab1,Pab1,P04147,,YES,181,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.767,-4.744,2.977,,,,,,,1.395,,73.83,BAH,-1.575,0.175299,0.00107557,0.904553 Pab1_E181E,Pab1_181,Pab1,Pab1,P04147,,YES,181,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.767,-1.767,,,,,,,,1.395,,73.83,BAH,-1.575,0.175299,0.00107557,0.843972 Pab1_E181M,Pab1_181,Pab1,Pab1,P04147,,YES,181,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.767,-4.597,2.83,,,,,,,1.395,,73.83,BAH,-1.575,0.175299,0.00107557,0.874013 Pab1_E181W,Pab1_181,Pab1,Pab1,P04147,,YES,181,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.767,-5.32,3.553,,,,,,,1.395,,73.83,BAH,-1.575,0.175299,0.00107557,0.862392 Pab1_E195C,Pab1_195,Pab1,Pab1,P04147,,YES,195,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.2,-5.123,3.923,,,,,,,,,,PAH,-1.72467,0.175299,0.000620107,0.896734 Pab1_E195E,Pab1_195,Pab1,Pab1,P04147,,YES,195,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.2,-1.2,,,,,,,,,,,PAH,-1.72467,0.175299,0.000620107,0.862345 Pab1_E195M,Pab1_195,Pab1,Pab1,P04147,,YES,195,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.2,-4.445,3.245,,,,,,,,,,PAH,-1.72467,0.175299,0.000620107,0.860948 Pab1_E195W,Pab1_195,Pab1,Pab1,P04147,,YES,195,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.2,-5.133,3.933,,,,,,,,,,PAH,-1.72467,0.175299,0.000620107,0.853597 Pab1_F129D,Pab1_129,Pab1,Pab1,P04147,,YES,129,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.269,-3.789,2.52,,0.219,E,B,0.03,-0.07,1.307,,73.83,HHH,-1.27533,0.175299,0.000625182,0.390559 Pab1_F129E,Pab1_129,Pab1,Pab1,P04147,,YES,129,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.269,-3.7,2.431,,0.219,E,B,0.03,-0.07,1.307,,73.83,HHH,-1.27533,0.175299,0.000625182,0.386578 Pab1_F129F,Pab1_129,Pab1,Pab1,P04147,,YES,129,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.269,-1.269,,,0.219,E,B,0.03,-0.07,1.307,,73.83,HHH,-1.27533,0.175299,0.000625182,0.622997 Pab1_F129K,Pab1_129,Pab1,Pab1,P04147,,YES,129,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.269,-3.717,2.448,,0.219,E,B,0.03,-0.07,1.307,,73.83,HHH,-1.27533,0.175299,0.000625182,0.394928 Pab1_F129P,Pab1_129,Pab1,Pab1,P04147,,YES,129,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.269,-4.14,2.871,,0.219,E,B,0.03,-0.07,1.307,,73.83,HHH,-1.27533,0.175299,0.000625182,0.478906 Pab1_F129Q,Pab1_129,Pab1,Pab1,P04147,,YES,129,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.269,-4.09,2.821,,0.219,E,B,0.03,-0.07,1.307,,73.83,HHH,-1.27533,0.175299,0.000625182,0.450978 Pab1_F146E,Pab1_146,Pab1,Pab1,P04147,,YES,146,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.149,-3.707,2.558,,0.006,H,A,,0.75,,,,PHP,-1.161,0.175299,0.000329265,0.608875 Pab1_F146F,Pab1_146,Pab1,Pab1,P04147,,YES,146,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.149,-1.149,,,0.006,H,A,,0.75,,,,PHP,-1.161,0.175299,0.000329265,0.782788 Pab1_F146K,Pab1_146,Pab1,Pab1,P04147,,YES,146,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.149,-3.724,2.575,,0.006,H,A,,0.75,,,,PHP,-1.161,0.175299,0.000329265,0.648517 Pab1_F146Q,Pab1_146,Pab1,Pab1,P04147,,YES,146,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.149,-4.166,3.017,,0.006,H,A,,0.75,,,,PHP,-1.161,0.175299,0.000329265,0.68875 Pab1_F149E,Pab1_149,Pab1,Pab1,P04147,,YES,149,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.149,-3.707,2.558,,0.183,T,A,1.33,1.09,,,,HHO,-1.27767,0.175299,0.000325688,0.471662 Pab1_F149F,Pab1_149,Pab1,Pab1,P04147,,YES,149,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.149,-1.149,,,0.183,T,A,1.33,1.09,,,,HHO,-1.27767,0.175299,0.000325688,0.680713 Pab1_F149K,Pab1_149,Pab1,Pab1,P04147,,YES,149,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.149,-3.724,2.575,,0.183,T,A,1.33,1.09,,,,HHO,-1.27767,0.175299,0.000325688,0.498809 Pab1_F149Q,Pab1_149,Pab1,Pab1,P04147,,YES,149,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.149,-4.166,3.017,,0.183,T,A,1.33,1.09,,,,HHO,-1.27767,0.175299,0.000325688,0.549155 Pab1_F168E,Pab1_168,Pab1,Pab1,P04147,,YES,168,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.269,-3.7,2.431,,,,,,,0.789,,56.33,OHO,-1.10033,0.175299,0.00064061,0.551588 Pab1_F168G,Pab1_168,Pab1,Pab1,P04147,,YES,168,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.269,-3.454,2.185,,,,,,,0.789,,56.33,OHO,-1.10033,0.175299,0.00064061,0.640954 Pab1_F168K,Pab1_168,Pab1,Pab1,P04147,,YES,168,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.269,-3.717,2.448,,,,,,,0.789,,56.33,OHO,-1.10033,0.175299,0.00064061,0.59469 Pab1_F168Q,Pab1_168,Pab1,Pab1,P04147,,YES,168,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.269,-4.09,2.821,,,,,,,0.789,,56.33,OHO,-1.10033,0.175299,0.00064061,0.611878 Pab1_F170D,Pab1_170,Pab1,Pab1,P04147,,YES,170,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.269,-3.789,2.52,,0.331,E,B,0.87,-1.31,2.061,,79.72,OHH,-1.06367,0.175299,0.000540225,0.354269 Pab1_F170E,Pab1_170,Pab1,Pab1,P04147,,YES,170,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.269,-3.7,2.431,,0.331,E,B,0.87,-1.31,2.061,,79.72,OHH,-1.06367,0.175299,0.000540225,0.362408 Pab1_F170K,Pab1_170,Pab1,Pab1,P04147,,YES,170,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.269,-3.717,2.448,,0.331,E,B,0.87,-1.31,2.061,,79.72,OHH,-1.06367,0.175299,0.000540225,0.374192 Pab1_F170P,Pab1_170,Pab1,Pab1,P04147,,YES,170,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.269,-4.14,2.871,,0.331,E,B,0.87,-1.31,2.061,,79.72,OHH,-1.06367,0.175299,0.000540225,0.456489 Pab1_F170Q,Pab1_170,Pab1,Pab1,P04147,,YES,170,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.269,-4.09,2.821,,0.331,E,B,0.87,-1.31,2.061,,79.72,OHH,-1.06367,0.175299,0.000540225,0.441478 Pab1_F173E,Pab1_173,Pab1,Pab1,P04147,,YES,173,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.477,-3.672,2.195,,,E,B,0.87,-0.16,1.636,,63.26,BHA,-1.36967,0.175299,0.00148779,0.196753 Pab1_F173K,Pab1_173,Pab1,Pab1,P04147,,YES,173,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.477,-3.689,2.212,,,E,B,0.87,-0.16,1.636,,63.26,BHA,-1.36967,0.175299,0.00148779,0.203372 Pab1_F173Q,Pab1_173,Pab1,Pab1,P04147,,YES,173,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.477,-4.012,2.535,,,E,B,0.87,-0.16,1.636,,63.26,BHA,-1.36967,0.175299,0.00148779,0.264591 Pab1_G126F,Pab1_126,Pab1,Pab1,P04147,,YES,126,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.985,-4.103,3.118,,0.011,T,A,0.46,-0.07,2.349,,80.42,OOP,-1.032,0.175299,0.00109814,0.768159 Pab1_G126G,Pab1_126,Pab1,Pab1,P04147,,YES,126,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.985,-0.985,,,0.011,T,A,0.46,-0.07,2.349,,80.42,OOP,-1.032,0.175299,0.00109814,0.815389 Pab1_G126H,Pab1_126,Pab1,Pab1,P04147,,YES,126,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.985,-4.55,3.565,,0.011,T,A,0.46,-0.07,2.349,,80.42,OOP,-1.032,0.175299,0.00109814,0.769247 Pab1_G126I,Pab1_126,Pab1,Pab1,P04147,,YES,126,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.985,-3.894,2.909,,0.011,T,A,0.46,-0.07,2.349,,80.42,OOP,-1.032,0.175299,0.00109814,0.761263 Pab1_G126K,Pab1_126,Pab1,Pab1,P04147,,YES,126,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.985,-3.492,2.507,,0.011,T,A,0.46,-0.07,2.349,,80.42,OOP,-1.032,0.175299,0.00109814,0.770974 Pab1_G126L,Pab1_126,Pab1,Pab1,P04147,,YES,126,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-0.985,-3.467,2.482,,0.011,T,A,0.46,-0.07,2.349,,80.42,OOP,-1.032,0.175299,0.00109814,0.779616 Pab1_G126M,Pab1_126,Pab1,Pab1,P04147,,YES,126,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.985,-4.67,3.685,,0.011,T,A,0.46,-0.07,2.349,,80.42,OOP,-1.032,0.175299,0.00109814,0.773219 Pab1_G126P,Pab1_126,Pab1,Pab1,P04147,,YES,126,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.985,-3.69,2.705,,0.011,T,A,0.46,-0.07,2.349,,80.42,OOP,-1.032,0.175299,0.00109814,0.699077 Pab1_G126Q,Pab1_126,Pab1,Pab1,P04147,,YES,126,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.985,-3.935,2.95,,0.011,T,A,0.46,-0.07,2.349,,80.42,OOP,-1.032,0.175299,0.00109814,0.760858 Pab1_G126T,Pab1_126,Pab1,Pab1,P04147,,YES,126,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.985,-3.387,2.402,,0.011,T,A,0.46,-0.07,2.349,,80.42,OOP,-1.032,0.175299,0.00109814,0.780953 Pab1_G126Y,Pab1_126,Pab1,Pab1,P04147,,YES,126,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.985,-4.198,3.213,,0.011,T,A,0.46,-0.07,2.349,,80.42,OOP,-1.032,0.175299,0.00109814,0.771218 Pab1_G150G,Pab1_150,Pab1,Pab1,P04147,,YES,150,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.809,-0.809,,,0.287,S,b,0.23,0.53,,,,HOA,-1.45233,0.175299,0.000323835,0.7245 Pab1_G150K,Pab1_150,Pab1,Pab1,P04147,,YES,150,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.809,-3.499,2.69,,0.287,S,b,0.23,0.53,,,,HOA,-1.45233,0.175299,0.000323835,0.63194 Pab1_G150M,Pab1_150,Pab1,Pab1,P04147,,YES,150,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.809,-4.747,3.938,,0.287,S,b,0.23,0.53,,,,HOA,-1.45233,0.175299,0.000323835,0.61054 Pab1_G150Q,Pab1_150,Pab1,Pab1,P04147,,YES,150,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.809,-3.941,3.132,,0.287,S,b,0.23,0.53,,,,HOA,-1.45233,0.175299,0.000323835,0.597461 Pab1_G163F,Pab1_163,Pab1,Pab1,P04147,,YES,163,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.809,-4.109,3.3,,0.356,B,g,,0.55,,,,POB,-1.80667,0.175299,0.00030953,0.810698 Pab1_G163H,Pab1_163,Pab1,Pab1,P04147,,YES,163,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.809,-4.497,3.688,,0.356,B,g,,0.55,,,,POB,-1.80667,0.175299,0.00030953,0.817341 Pab1_G163M,Pab1_163,Pab1,Pab1,P04147,,YES,163,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.809,-4.747,3.938,,0.356,B,g,,0.55,,,,POB,-1.80667,0.175299,0.00030953,0.818304 Pab1_G163N,Pab1_163,Pab1,Pab1,P04147,,YES,163,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.809,-3.265,2.456,,0.356,B,g,,0.55,,,,POB,-1.80667,0.175299,0.00030953,0.863266 Pab1_G163Y,Pab1_163,Pab1,Pab1,P04147,,YES,163,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.809,-4.205,3.396,,0.356,B,g,,0.55,,,,POB,-1.80667,0.175299,0.00030953,0.813597 Pab1_G167K,Pab1_167,Pab1,Pab1,P04147,,YES,167,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.223,-2.365,1.142,,0.195,S,g,,0.03,,,,BOH,-1.25133,0.175299,0.00146449,0.843866 Pab1_G167M,Pab1_167,Pab1,Pab1,P04147,,YES,167,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.223,-4.635,3.412,,0.195,S,g,,0.03,,,,BOH,-1.25133,0.175299,0.00146449,0.806041 Pab1_G167Q,Pab1_167,Pab1,Pab1,P04147,,YES,167,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.223,-3.944,2.721,,0.195,S,g,,0.03,,,,BOH,-1.25133,0.175299,0.00146449,0.797645 Pab1_G169F,Pab1_169,Pab1,Pab1,P04147,,YES,169,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.809,-4.109,3.3,,,E,b,0.35,0.03,,,,HOH,-1.11567,0.175299,0.000302434,0.56894 Pab1_G169H,Pab1_169,Pab1,Pab1,P04147,,YES,169,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.809,-4.497,3.688,,,E,b,0.35,0.03,,,,HOH,-1.11567,0.175299,0.000302434,0.604541 Pab1_G169I,Pab1_169,Pab1,Pab1,P04147,,YES,169,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.809,-4.052,3.243,,,E,b,0.35,0.03,,,,HOH,-1.11567,0.175299,0.000302434,0.562755 Pab1_G169N,Pab1_169,Pab1,Pab1,P04147,,YES,169,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-0.809,-3.265,2.456,,,E,b,0.35,0.03,,,,HOH,-1.11567,0.175299,0.000302434,0.583664 Pab1_G169Y,Pab1_169,Pab1,Pab1,P04147,,YES,169,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.809,-4.205,3.396,,,E,b,0.35,0.03,,,,HOH,-1.11567,0.175299,0.000302434,0.607496 Pab1_G177G,Pab1_177,Pab1,Pab1,P04147,,YES,177,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-2.24,-2.24,,,,,,,,,,,AOH,-1.94067,0.175299,0.00170727,0.892456 Pab1_G177K,Pab1_177,Pab1,Pab1,P04147,,YES,177,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-2.24,-3.254,1.014,,,,,,,,,,AOH,-1.94067,0.175299,0.00170727,0.869192 Pab1_G177M,Pab1_177,Pab1,Pab1,P04147,,YES,177,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-2.24,-4.628,2.388,,,,,,,,,,AOH,-1.94067,0.175299,0.00170727,0.853503 Pab1_G177Q,Pab1_177,Pab1,Pab1,P04147,,YES,177,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-2.24,-3.601,1.361,,,,,,,,,,AOH,-1.94067,0.175299,0.00170727,0.851453 Pab1_G188G,Pab1_188,Pab1,Pab1,P04147,,YES,188,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.809,-0.809,,,0.379,E,g,,2.18,,,,POH,-1.14633,0.175299,0.000280911,0.846584 Pab1_G188K,Pab1_188,Pab1,Pab1,P04147,,YES,188,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.809,-3.499,2.69,,0.379,E,g,,2.18,,,,POH,-1.14633,0.175299,0.000280911,0.854354 Pab1_G188M,Pab1_188,Pab1,Pab1,P04147,,YES,188,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-0.809,-4.747,3.938,,0.379,E,g,,2.18,,,,POH,-1.14633,0.175299,0.000280911,0.826288 Pab1_G188Q,Pab1_188,Pab1,Pab1,P04147,,YES,188,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.809,-3.941,3.132,,0.379,E,g,,2.18,,,,POH,-1.14633,0.175299,0.000280911,0.836342 Pab1_G193G,Pab1_193,Pab1,Pab1,P04147,,YES,193,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.414,-1.414,,,,,,,,,,,POP,-1.55733,0.175299,0.0014922,0.897554 Pab1_G193K,Pab1_193,Pab1,Pab1,P04147,,YES,193,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.414,-3.423,2.009,,,,,,,,,,POP,-1.55733,0.175299,0.0014922,0.867288 Pab1_G193M,Pab1_193,Pab1,Pab1,P04147,,YES,193,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.414,-4.814,3.4,,,,,,,,,,POP,-1.55733,0.175299,0.0014922,0.857923 Pab1_G193Q,Pab1_193,Pab1,Pab1,P04147,,YES,193,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.414,-3.784,2.37,,,,,,,,,,POP,-1.55733,0.175299,0.0014922,0.850053 Pab1_H134H,Pab1_134,Pab1,Pab1,P04147,,YES,134,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-1.542,-1.542,,,,,,,,,,,HBO,-1.346,0.175299,0.00116356,0.889488 Pab1_H134W,Pab1_134,Pab1,Pab1,P04147,,YES,134,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-1.542,-5.205,3.663,,,,,,,,,,HBO,-1.346,0.175299,0.00116356,0.85332 Pab1_H172M,Pab1_172,Pab1,Pab1,P04147,,YES,172,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-1.21,-4.522,3.312,,0.076,E,B,0.35,-0.87,,,,HBH,-1.26667,0.175299,0.000296642,0.52735 Pab1_H172W,Pab1_172,Pab1,Pab1,P04147,,YES,172,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-1.21,-4.915,3.705,,0.076,E,B,0.35,-0.87,,,,HBH,-1.26667,0.175299,0.000296642,0.521118 Pab1_I128D,Pab1_128,Pab1,Pab1,P04147,,YES,128,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.345,-3.811,2.466,,0.008,E,B,1.68,-0.6,1.706,,78.68,PHH,-1.231,0.175299,0.00104192,0.245996 Pab1_I128E,Pab1_128,Pab1,Pab1,P04147,,YES,128,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.345,-3.703,2.358,,0.008,E,B,1.68,-0.6,1.706,,78.68,PHH,-1.231,0.175299,0.00104192,0.243877 Pab1_I128I,Pab1_128,Pab1,Pab1,P04147,,YES,128,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.345,-1.345,,,0.008,E,B,1.68,-0.6,1.706,,78.68,PHH,-1.231,0.175299,0.00104192,0.613134 Pab1_I128Q,Pab1_128,Pab1,Pab1,P04147,,YES,128,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.345,-4.163,2.818,,0.008,E,B,1.68,-0.6,1.706,,78.68,PHH,-1.231,0.175299,0.00104192,0.362442 Pab1_I128W,Pab1_128,Pab1,Pab1,P04147,,YES,128,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.345,-5.215,3.87,,0.008,E,B,1.68,-0.6,1.706,,78.68,PHH,-1.231,0.175299,0.00104192,0.354706 Pab1_I130E,Pab1_130,Pab1,Pab1,P04147,,YES,130,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.212,-3.707,2.495,,,E,B,1.23,0.01,,,,HHB,-1.188,0.175299,0.000351112,0.299958 Pab1_I130I,Pab1_130,Pab1,Pab1,P04147,,YES,130,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.212,-1.212,,,,E,B,1.23,0.01,,,,HHB,-1.188,0.175299,0.000351112,0.712063 Pab1_I130Q,Pab1_130,Pab1,Pab1,P04147,,YES,130,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.212,-4.166,2.954,,,E,B,1.23,0.01,,,,HHB,-1.188,0.175299,0.000351112,0.42548 Pab1_I130W,Pab1_130,Pab1,Pab1,P04147,,YES,130,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.212,-5.14,3.928,,,E,B,1.23,0.01,,,,HHB,-1.188,0.175299,0.000351112,0.435337 Pab1_I137E,Pab1_137,Pab1,Pab1,P04147,,YES,137,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.212,-3.707,2.495,,0.068,,B,0.77,0.35,,,,AHA,-1.314,0.175299,0.000342224,0.512328 Pab1_I137I,Pab1_137,Pab1,Pab1,P04147,,YES,137,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.212,-1.212,,,0.068,,B,0.77,0.35,,,,AHA,-1.314,0.175299,0.000342224,0.742537 Pab1_I137Q,Pab1_137,Pab1,Pab1,P04147,,YES,137,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.212,-4.166,2.954,,0.068,,B,0.77,0.35,,,,AHA,-1.314,0.175299,0.000342224,0.595292 Pab1_I137W,Pab1_137,Pab1,Pab1,P04147,,YES,137,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.212,-5.14,3.928,,0.068,,B,0.77,0.35,,,,AHA,-1.314,0.175299,0.000342224,0.579115 Pab1_I152E,Pab1_152,Pab1,Pab1,P04147,,YES,152,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.345,-3.703,2.358,,0.165,E,B,1.23,-0.71,1.288,,71.4,AHH,-1.59433,0.175299,0.000740963,0.272838 Pab1_I152I,Pab1_152,Pab1,Pab1,P04147,,YES,152,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.345,-1.345,,,0.165,E,B,1.23,-0.71,1.288,,71.4,AHH,-1.59433,0.175299,0.000740963,0.593211 Pab1_I152Q,Pab1_152,Pab1,Pab1,P04147,,YES,152,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.345,-4.163,2.818,,0.165,E,B,1.23,-0.71,1.288,,71.4,AHH,-1.59433,0.175299,0.000740963,0.36536 Pab1_I152W,Pab1_152,Pab1,Pab1,P04147,,YES,152,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.345,-5.215,3.87,,0.165,E,B,1.23,-0.71,1.288,,71.4,AHH,-1.59433,0.175299,0.000740963,0.362927 Pab1_I157E,Pab1_157,Pab1,Pab1,P04147,,YES,157,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.623,-3.647,2.024,,,,,,,1.439,,79.72,BHH,-1.28667,0.175299,0.0018103,0.576835 Pab1_I157I,Pab1_157,Pab1,Pab1,P04147,,YES,157,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.623,-1.623,,,,,,,,1.439,,79.72,BHH,-1.28667,0.175299,0.0018103,0.703529 Pab1_I157Q,Pab1_157,Pab1,Pab1,P04147,,YES,157,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.623,-4.106,2.483,,,,,,,1.439,,79.72,BHH,-1.28667,0.175299,0.0018103,0.708582 Pab1_I157W,Pab1_157,Pab1,Pab1,P04147,,YES,157,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.623,-5.211,3.588,,,,,,,1.439,,79.72,BHH,-1.28667,0.175299,0.0018103,0.692167 Pab1_I183E,Pab1_183,Pab1,Pab1,P04147,,YES,183,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.302,-3.7,2.398,,0.308,T,B,1,1.08,1.29,,75.56,HHA,-1.27167,0.175299,0.000574345,0.740051 Pab1_I183I,Pab1_183,Pab1,Pab1,P04147,,YES,183,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.302,-1.302,,,0.308,T,B,1,1.08,1.29,,75.56,HHA,-1.27167,0.175299,0.000574345,0.805133 Pab1_I183W,Pab1_183,Pab1,Pab1,P04147,,YES,183,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.302,-5.193,3.891,,0.308,T,B,1,1.08,1.29,,75.56,HHA,-1.27167,0.175299,0.000574345,0.777384 Pab1_I196E,Pab1_196,Pab1,Pab1,P04147,,YES,196,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.795,-3.625,1.83,,,,,,,2.013,,80.59,AHH,-1.44667,0.175299,0.0016933,0.57325 Pab1_I196I,Pab1_196,Pab1,Pab1,P04147,,YES,196,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.795,-1.795,,,,,,,,2.013,,80.59,AHH,-1.44667,0.175299,0.0016933,0.687886 Pab1_I196Q,Pab1_196,Pab1,Pab1,P04147,,YES,196,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.795,-4.085,2.29,,,,,,,2.013,,80.59,AHH,-1.44667,0.175299,0.0016933,0.685379 Pab1_I196W,Pab1_196,Pab1,Pab1,P04147,,YES,196,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.795,-5.215,3.42,,,,,,,2.013,,80.59,AHH,-1.44667,0.175299,0.0016933,0.701113 Pab1_K131F,Pab1_131,Pab1,Pab1,P04147,,YES,131,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.083,-4.109,3.026,,0.462,E,B,1.82,0.57,,,,HBP,-1.12467,0.175299,0.000349395,0.441908 Pab1_K131K,Pab1_131,Pab1,Pab1,P04147,,YES,131,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.083,-1.083,,,0.462,E,B,1.82,0.57,,,,HBP,-1.12467,0.175299,0.000349395,0.648927 Pab1_K140C,Pab1_140,Pab1,Pab1,P04147,,YES,140,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.083,-4.904,3.821,,0.345,H,A,,-0.73,,,,PBH,-1.20767,0.175299,0.000337366,0.851142 Pab1_K140F,Pab1_140,Pab1,Pab1,P04147,,YES,140,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.083,-4.109,3.026,,0.345,H,A,,-0.73,,,,PBH,-1.20767,0.175299,0.000337366,0.816901 Pab1_K140K,Pab1_140,Pab1,Pab1,P04147,,YES,140,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.083,-1.083,,,0.345,H,A,,-0.73,,,,PBH,-1.20767,0.175299,0.000337366,0.846219 Pab1_K156C,Pab1_156,Pab1,Pab1,P04147,,YES,156,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.083,-4.904,3.821,,0.406,E,B,1.82,-0.26,,,,PBH,-1.58167,0.175299,0.000316767,0.544678 Pab1_K156F,Pab1_156,Pab1,Pab1,P04147,,YES,156,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.083,-4.109,3.026,,0.406,E,B,1.82,-0.26,,,,PBH,-1.58167,0.175299,0.000316767,0.499946 Pab1_K156K,Pab1_156,Pab1,Pab1,P04147,,YES,156,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.083,-1.083,,,0.406,E,B,1.82,-0.26,,,,PBH,-1.58167,0.175299,0.000316767,0.645628 Pab1_K164C,Pab1_164,Pab1,Pab1,P04147,,YES,164,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-2.298,-5.001,2.703,,,,,,,,,,OBP,-1.41767,0.175299,0.00255241,0.899951 Pab1_K164W,Pab1_164,Pab1,Pab1,P04147,,YES,164,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-2.298,-5.375,3.077,,,,,,,,,,OBP,-1.41767,0.175299,0.00255241,0.860172 Pab1_K166C,Pab1_166,Pab1,Pab1,P04147,,YES,166,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.262,-4.98,3.718,,0.299,,l,,0,,,,PBO,-1.21033,0.175299,0.0011038,0.833483 Pab1_K166F,Pab1_166,Pab1,Pab1,P04147,,YES,166,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.262,-4.185,2.923,,0.299,,l,,0,,,,PBO,-1.21033,0.175299,0.0011038,0.801591 Pab1_K180C,Pab1_180,Pab1,Pab1,P04147,,YES,180,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.945,-5.089,3.144,,,,,,,,,,HBA,-1.575,0.175299,0.00295933,0.899184 Pab1_K180F,Pab1_180,Pab1,Pab1,P04147,,YES,180,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.945,-4.295,2.35,,,,,,,,,,HBA,-1.575,0.175299,0.00295933,0.858701 Pab1_K180K,Pab1_180,Pab1,Pab1,P04147,,YES,180,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.945,-1.945,,,,,,,,,,,HBA,-1.575,0.175299,0.00295933,0.881432 Pab1_L133D,Pab1_133,Pab1,Pab1,P04147,,YES,133,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.039,-3.961,2.922,,0.015,,B,1.75,1.03,,,,PHB,-1.22,0.175299,0.000345939,0.429046 Pab1_L133G,Pab1_133,Pab1,Pab1,P04147,,YES,133,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.039,-3.625,2.586,,0.015,,B,1.75,1.03,,,,PHB,-1.22,0.175299,0.000345939,0.45266 Pab1_L133H,Pab1_133,Pab1,Pab1,P04147,,YES,133,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.039,-4.722,3.683,,0.015,,B,1.75,1.03,,,,PHB,-1.22,0.175299,0.000345939,0.499572 Pab1_L133L,Pab1_133,Pab1,Pab1,P04147,,YES,133,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.039,-1.039,,,0.015,,B,1.75,1.03,,,,PHB,-1.22,0.175299,0.000345939,0.704863 Pab1_L133N,Pab1_133,Pab1,Pab1,P04147,,YES,133,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.039,-3.94,2.901,,0.015,,B,1.75,1.03,,,,PHB,-1.22,0.175299,0.000345939,0.472843 Pab1_L142D,Pab1_142,Pab1,Pab1,P04147,,YES,142,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.039,-3.961,2.922,,0.007,H,A,0.84,-0.65,,,,HHH,-1.487,0.175299,0.000335477,0.530454 Pab1_L142E,Pab1_142,Pab1,Pab1,P04147,,YES,142,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.039,-3.707,2.668,,0.007,H,A,0.84,-0.65,,,,HHH,-1.487,0.175299,0.000335477,0.513828 Pab1_L142H,Pab1_142,Pab1,Pab1,P04147,,YES,142,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.039,-4.722,3.683,,0.007,H,A,0.84,-0.65,,,,HHH,-1.487,0.175299,0.000335477,0.593777 Pab1_L142L,Pab1_142,Pab1,Pab1,P04147,,YES,142,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.039,-1.039,,,0.007,H,A,0.84,-0.65,,,,HHH,-1.487,0.175299,0.000335477,0.747189 Pab1_L142N,Pab1_142,Pab1,Pab1,P04147,,YES,142,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.039,-3.94,2.901,,0.007,H,A,0.84,-0.65,,,,HHH,-1.487,0.175299,0.000335477,0.569194 Pab1_L153D,Pab1_153,Pab1,Pab1,P04147,,YES,153,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.039,-3.961,2.922,,0.46,E,A,,-0.95,,,,HHP,-1.17667,0.175299,0.000321212,0.684298 Pab1_L153H,Pab1_153,Pab1,Pab1,P04147,,YES,153,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.039,-4.722,3.683,,0.46,E,A,,-0.95,,,,HHP,-1.17667,0.175299,0.000321212,0.734857 Pab1_L153L,Pab1_153,Pab1,Pab1,P04147,,YES,153,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.039,-1.039,,,0.46,E,A,,-0.95,,,,HHP,-1.17667,0.175299,0.000321212,0.744011 Pab1_L153N,Pab1_153,Pab1,Pab1,P04147,,YES,153,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.039,-3.94,2.901,,0.46,E,A,,-0.95,,,,HHP,-1.17667,0.175299,0.000321212,0.707737 Pab1_L186D,Pab1_186,Pab1,Pab1,P04147,,YES,186,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.783,-3.916,2.133,,,,,,,,,,HHP,-1.56967,0.175299,0.00154968,0.664077 Pab1_L186H,Pab1_186,Pab1,Pab1,P04147,,YES,186,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.783,-4.851,3.068,,,,,,,,,,HHP,-1.56967,0.175299,0.00154968,0.770174 Pab1_L186L,Pab1_186,Pab1,Pab1,P04147,,YES,186,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.783,-1.783,,,,,,,,,,,HHP,-1.56967,0.175299,0.00154968,0.826131 Pab1_L186N,Pab1_186,Pab1,Pab1,P04147,,YES,186,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.783,-4.068,2.285,,,,,,,,,,HHP,-1.56967,0.175299,0.00154968,0.749271 Pab1_L190C,Pab1_190,Pab1,Pab1,P04147,,YES,190,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.325,-4.569,3.244,,0.489,E,B,,2.59,,,,HHH,-1.31033,0.175299,0.00132347,0.825381 Pab1_L190D,Pab1_190,Pab1,Pab1,P04147,,YES,190,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.325,-3.792,2.467,,0.489,E,B,,2.59,,,,HHH,-1.31033,0.175299,0.00132347,0.840498 Pab1_L190L,Pab1_190,Pab1,Pab1,P04147,,YES,190,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.325,-1.325,,,0.489,E,B,,2.59,,,,HHH,-1.31033,0.175299,0.00132347,0.891667 Pab1_L190N,Pab1_190,Pab1,Pab1,P04147,,YES,190,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.325,-3.771,2.446,,0.489,E,B,,2.59,,,,HHH,-1.31033,0.175299,0.00132347,0.854526 Pab1_L190Y,Pab1_190,Pab1,Pab1,P04147,,YES,190,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.325,-3.906,2.581,,0.489,E,B,,2.59,,,,HHH,-1.31033,0.175299,0.00132347,0.844487 Pab1_L191D,Pab1_191,Pab1,Pab1,P04147,,YES,191,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.2,-3.957,2.757,,0.204,E,B,,2.24,,,,HHP,-1.20133,0.175299,0.000583797,0.784929 Pab1_L191L,Pab1_191,Pab1,Pab1,P04147,,YES,191,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.2,-1.2,,,0.204,E,B,,2.24,,,,HHP,-1.20133,0.175299,0.000583797,0.893258 Pab1_L191N,Pab1_191,Pab1,Pab1,P04147,,YES,191,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.2,-3.937,2.737,,0.204,E,B,,2.24,,,,HHP,-1.20133,0.175299,0.000583797,0.810167 Pab1_M189C,Pab1_189,Pab1,Pab1,P04147,,YES,189,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.406,-4.454,3.048,,0.631,E,b,,2.81,,,,OHH,-1.18,0.175299,0.000278756,0.816542 Pab1_M189D,Pab1_189,Pab1,Pab1,P04147,,YES,189,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.406,-3.736,2.33,,0.631,E,b,,2.81,,,,OHH,-1.18,0.175299,0.000278756,0.812133 Pab1_M189H,Pab1_189,Pab1,Pab1,P04147,,YES,189,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.406,-4.497,3.091,,0.631,E,b,,2.81,,,,OHH,-1.18,0.175299,0.000278756,0.82797 Pab1_M189M,Pab1_189,Pab1,Pab1,P04147,,YES,189,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.406,-1.406,,,0.631,E,b,,2.81,,,,OHH,-1.18,0.175299,0.000278756,0.87432 Pab1_M189Y,Pab1_189,Pab1,Pab1,P04147,,YES,189,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.406,-3.755,2.349,,0.631,E,b,,2.81,,,,OHH,-1.18,0.175299,0.000278756,0.832929 Pab1_N127M,Pab1_127,Pab1,Pab1,P04147,,YES,127,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-1.079,-4.522,3.443,,0.138,E,B,1.05,-0.51,,,,OPH,-1.13633,0.175299,0.000805159,0.359176 Pab1_N127N,Pab1_127,Pab1,Pab1,P04147,,YES,127,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-1.079,-1.079,,,0.138,E,B,1.05,-0.51,,,,OPH,-1.13633,0.175299,0.000805159,0.54942 Pab1_N127W,Pab1_127,Pab1,Pab1,P04147,,YES,127,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-1.079,-5.365,4.286,,0.138,E,B,1.05,-0.51,,,,OPH,-1.13633,0.175299,0.000805159,0.352093 Pab1_N132N,Pab1_132,Pab1,Pab1,P04147,,YES,132,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-1.079,-1.079,,,0.412,S,l,,0.9,,,,BPH,-1.067,0.175299,0.000347671,0.891786 Pab1_N132W,Pab1_132,Pab1,Pab1,P04147,,YES,132,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-1.079,-5.365,4.286,,0.412,S,l,,0.9,,,,BPH,-1.067,0.175299,0.000347671,0.843614 Pab1_N139N,Pab1_139,Pab1,Pab1,P04147,,YES,139,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-1.079,-1.079,,,0.062,H,A,,-0.73,,,,APB,-1.09667,0.175299,0.000339145,0.847722 Pab1_N139W,Pab1_139,Pab1,Pab1,P04147,,YES,139,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-1.079,-5.365,4.286,,0.062,H,A,,-0.73,,,,APB,-1.09667,0.175299,0.000339145,0.797676 Pab1_N162W,Pab1_162,Pab1,Pab1,P04147,,YES,162,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-2.313,-5.183,2.87,,0.681,T,A,,1.12,,,,APO,-1.532,0.175299,0.0030719,0.864038 Pab1_N187N,Pab1_187,Pab1,Pab1,P04147,,YES,187,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-1.224,-1.224,,,0.456,S,b,,1.87,,,,HPO,-1.272,0.175299,0.00083165,0.892162 Pab1_N187W,Pab1_187,Pab1,Pab1,P04147,,YES,187,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-1.224,-5.418,4.194,,0.456,S,b,,1.87,,,,HPO,-1.272,0.175299,0.00083165,0.850484 Pab1_N192N,Pab1_192,Pab1,Pab1,P04147,,YES,192,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-1.079,-1.079,,,0.619,T,l,,2.28,,,,HPO,-1.231,0.175299,0.000273498,0.899911 Pab1_P135E,Pab1_135,Pab1,Pab1,P04147,,YES,135,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.457,-3.236,1.779,,,,,,,6.41,,81.8,BOA,-1.53367,0.175299,0.00148028,0.914024 Pab1_P135K,Pab1_135,Pab1,Pab1,P04147,,YES,135,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.457,-3.305,1.848,,,,,,,6.41,,81.8,BOA,-1.53367,0.175299,0.00148028,0.91185 Pab1_P135M,Pab1_135,Pab1,Pab1,P04147,,YES,135,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.457,-4.503,3.046,,,,,,,6.41,,81.8,BOA,-1.53367,0.175299,0.00148028,0.899415 Pab1_P135P,Pab1_135,Pab1,Pab1,P04147,,YES,135,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.457,-1.457,,,,,,,,6.41,,81.8,BOA,-1.53367,0.175299,0.00148028,0.88071 Pab1_P135W,Pab1_135,Pab1,Pab1,P04147,,YES,135,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.457,-5.345,3.888,,,,,,,6.41,,81.8,BOA,-1.53367,0.175299,0.00148028,0.897359 Pab1_P200C,Pab1_200,Pab1,Pab1,P04147,,YES,200,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.871,-4.886,3.015,,,,,,,3.877,,80.59,HOO,-1.7005,0.175299,0.00190795,0.923708 Pab1_P200E,Pab1_200,Pab1,Pab1,P04147,,YES,200,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.871,-3.376,1.505,,,,,,,3.877,,80.59,HOO,-1.7005,0.175299,0.00190795,0.9132 Pab1_P200K,Pab1_200,Pab1,Pab1,P04147,,YES,200,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.871,-2.272,0.401,,,,,,,3.877,,80.59,HOO,-1.7005,0.175299,0.00190795,0.910251 Pab1_P200M,Pab1_200,Pab1,Pab1,P04147,,YES,200,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.871,-2.919,1.048,,,,,,,3.877,,80.59,HOO,-1.7005,0.175299,0.00190795,0.914486 Pab1_P200P,Pab1_200,Pab1,Pab1,P04147,,YES,200,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.871,-1.871,,,,,,,,3.877,,80.59,HOO,-1.7005,0.175299,0.00190795,0.888644 Pab1_P200W,Pab1_200,Pab1,Pab1,P04147,,YES,200,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.871,-2.893,1.022,,,,,,,3.877,,80.59,HOO,-1.7005,0.175299,0.00190795,0.914997 Pab1_P200Y,Pab1_200,Pab1,Pab1,P04147,,YES,200,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.871,,,,,,,,,3.877,,80.59,HOO,-1.7005,0.175299,0.00190795,0.910355 Pab1_Q194F,Pab1_194,Pab1,Pab1,P04147,,YES,194,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-2.179,-4.013,1.834,,,,,,,,,,OPA,-1.59767,0.175299,0.0016145,0.85911 Pab1_Q194M,Pab1_194,Pab1,Pab1,P04147,,YES,194,Q,M,QM,Polar,Hydrophobic,6.24429,5.74,-0.504286,101,146,149,3,143.8,162.9,19.1,-2.179,-2.902,0.723,,,,,,,,,,OPA,-1.59767,0.175299,0.0016145,0.88488 Pab1_Q194Q,Pab1_194,Pab1,Pab1,P04147,,YES,194,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-2.179,-2.179,,,,,,,,,,,OPA,-1.59767,0.175299,0.0016145,0.886471 Pab1_Q194W,Pab1_194,Pab1,Pab1,P04147,,YES,194,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-2.179,-5.187,3.008,,,,,,,,,,OPA,-1.59767,0.175299,0.0016145,0.862675 Pab1_S147E,Pab1_147,Pab1,Pab1,P04147,,YES,147,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.267,-3.136,1.869,,0.336,H,A,,0.56,,,,HPH,-1.43033,0.175299,0.000610856,0.817161 Pab1_S147K,Pab1_147,Pab1,Pab1,P04147,,YES,147,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.267,-3.153,1.886,,0.336,H,A,,0.56,,,,HPH,-1.43033,0.175299,0.000610856,0.855095 Pab1_S147M,Pab1_147,Pab1,Pab1,P04147,,YES,147,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.267,-4.35,3.083,,0.336,H,A,,0.56,,,,HPH,-1.43033,0.175299,0.000610856,0.838156 Pab1_S147Q,Pab1_147,Pab1,Pab1,P04147,,YES,147,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.267,-3.595,2.328,,0.336,H,A,,0.56,,,,HPH,-1.43033,0.175299,0.000610856,0.839425 Pab1_S147S,Pab1_147,Pab1,Pab1,P04147,,YES,147,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.267,-1.267,,,0.336,H,A,,0.56,,,,HPH,-1.43033,0.175299,0.000610856,0.8691 Pab1_S154E,Pab1_154,Pab1,Pab1,P04147,,YES,154,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.146,-3.032,1.886,,0.208,E,B,0.1,-0.75,,,,HPP,-1.408,0.175299,0.000319331,0.448352 Pab1_S154K,Pab1_154,Pab1,Pab1,P04147,,YES,154,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.146,-3.049,1.903,,0.208,E,B,0.1,-0.75,,,,HPP,-1.408,0.175299,0.000319331,0.435021 Pab1_S154M,Pab1_154,Pab1,Pab1,P04147,,YES,154,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.146,-4.297,3.151,,0.208,E,B,0.1,-0.75,,,,HPP,-1.408,0.175299,0.000319331,0.516867 Pab1_S154N,Pab1_154,Pab1,Pab1,P04147,,YES,154,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.146,-3.04,1.894,,0.208,E,B,0.1,-0.75,,,,HPP,-1.408,0.175299,0.000319331,0.467311 Pab1_S154Q,Pab1_154,Pab1,Pab1,P04147,,YES,154,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.146,-3.491,2.345,,0.208,E,B,0.1,-0.75,,,,HPP,-1.408,0.175299,0.000319331,0.426066 Pab1_S154S,Pab1_154,Pab1,Pab1,P04147,,YES,154,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.146,-1.146,,,0.208,E,B,0.1,-0.75,,,,HPP,-1.408,0.175299,0.000319331,0.645246 Pab1_S155Q,Pab1_155,Pab1,Pab1,P04147,,YES,155,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-2.039,-4.016,1.977,,,,,,,,,,PPB,-1.42267,0.175299,0.00208179,0.785834 Pab1_S155S,Pab1_155,Pab1,Pab1,P04147,,YES,155,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-2.039,-2.039,,,,,,,,,,,PPB,-1.42267,0.175299,0.00208179,0.830078 Pab1_S165E,Pab1_165,Pab1,Pab1,P04147,,YES,165,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.146,-3.032,1.886,,0.12,,a,,0.11,,,,BPB,-1.56867,0.175299,0.000307838,0.786312 Pab1_S165K,Pab1_165,Pab1,Pab1,P04147,,YES,165,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.146,-3.049,1.903,,0.12,,a,,0.11,,,,BPB,-1.56867,0.175299,0.000307838,0.825017 Pab1_S165M,Pab1_165,Pab1,Pab1,P04147,,YES,165,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.146,-4.297,3.151,,0.12,,a,,0.11,,,,BPB,-1.56867,0.175299,0.000307838,0.806664 Pab1_S165Q,Pab1_165,Pab1,Pab1,P04147,,YES,165,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.146,-3.491,2.345,,0.12,,a,,0.11,,,,BPB,-1.56867,0.175299,0.000307838,0.818243 Pab1_T145E,Pab1_145,Pab1,Pab1,P04147,,YES,145,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.067,-3.257,2.19,,0.237,H,A,0.3,0.69,,,,APH,-1.135,0.175299,0.000331088,0.817051 Pab1_T145Q,Pab1_145,Pab1,Pab1,P04147,,YES,145,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.067,-3.716,2.649,,0.237,H,A,0.3,0.69,,,,APH,-1.135,0.175299,0.000331088,0.821938 Pab1_T145T,Pab1_145,Pab1,Pab1,P04147,,YES,145,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.067,-1.067,,,0.237,H,A,0.3,0.69,,,,APH,-1.135,0.175299,0.000331088,0.887918 Pab1_T145W,Pab1_145,Pab1,Pab1,P04147,,YES,145,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.067,-4.915,3.848,,0.237,H,A,0.3,0.69,,,,APH,-1.135,0.175299,0.000331088,0.819593 Pab1_T159E,Pab1_159,Pab1,Pab1,P04147,,YES,159,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.445,-3.407,1.962,,,,,,,2.531,,79.03,HPA,-1.19467,0.175299,0.00133849,0.88201 Pab1_T159Q,Pab1_159,Pab1,Pab1,P04147,,YES,159,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.445,-3.84,2.395,,,,,,,2.531,,79.03,HPA,-1.19467,0.175299,0.00133849,0.880722 Pab1_T159W,Pab1_159,Pab1,Pab1,P04147,,YES,159,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.445,-5.143,3.698,,,,,,,2.531,,79.03,HPA,-1.19467,0.175299,0.00133849,0.875468 Pab1_V148C,Pab1_148,Pab1,Pab1,P04147,,YES,148,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.875,-4.545,2.67,,,,,,,,,,PHH,-1.43033,0.175299,0.00179641,0.834189 Pab1_V148H,Pab1_148,Pab1,Pab1,P04147,,YES,148,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.875,-4.679,2.804,,,,,,,,,,PHH,-1.43033,0.175299,0.00179641,0.767757 Pab1_V148N,Pab1_148,Pab1,Pab1,P04147,,YES,148,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.875,-3.658,1.783,,,,,,,,,,PHH,-1.43033,0.175299,0.00179641,0.737117 Pab1_V148V,Pab1_148,Pab1,Pab1,P04147,,YES,148,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.875,-1.875,,,,,,,,,,,PHH,-1.43033,0.175299,0.00179641,0.827527 Pab1_V148Y,Pab1_148,Pab1,Pab1,P04147,,YES,148,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.875,-4.07,2.195,,,,,,,,,,PHH,-1.43033,0.175299,0.00179641,0.716362 Pab1_V171H,Pab1_171,Pab1,Pab1,P04147,,YES,171,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.113,-4.722,3.609,,0.008,E,b,0.23,-0.34,,,,HHB,-1.19733,0.175299,0.000298662,0.607105 Pab1_V171K,Pab1_171,Pab1,Pab1,P04147,,YES,171,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.113,-3.499,2.386,,0.008,E,b,0.23,-0.34,,,,HHB,-1.19733,0.175299,0.000298662,0.540336 Pab1_V171Q,Pab1_171,Pab1,Pab1,P04147,,YES,171,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.113,-3.941,2.828,,0.008,E,b,0.23,-0.34,,,,HHB,-1.19733,0.175299,0.000298662,0.543889 Pab1_V171R,Pab1_171,Pab1,Pab1,P04147,,YES,171,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.113,-3.975,2.862,,0.008,E,b,0.23,-0.34,,,,HHB,-1.19733,0.175299,0.000298662,0.559419 Pab1_V171W,Pab1_171,Pab1,Pab1,P04147,,YES,171,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.113,-5.14,4.027,,0.008,E,b,0.23,-0.34,,,,HHB,-1.19733,0.175299,0.000298662,0.612607 Pab1_V198E,Pab1_198,Pab1,Pab1,P04147,,YES,198,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.113,-3.482,2.369,,0.008,E,B,0.61,0.91,,,,HHH,-1.32933,0.175299,0.000268557,0.677265 Pab1_V198K,Pab1_198,Pab1,Pab1,P04147,,YES,198,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.113,-3.499,2.386,,0.008,E,B,0.61,0.91,,,,HHH,-1.32933,0.175299,0.000268557,0.681212 Pab1_V198N,Pab1_198,Pab1,Pab1,P04147,,YES,198,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.113,-3.94,2.827,,0.008,E,B,0.61,0.91,,,,HHH,-1.32933,0.175299,0.000268557,0.664242 Pab1_V198Q,Pab1_198,Pab1,Pab1,P04147,,YES,198,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.113,-3.941,2.828,,0.008,E,B,0.61,0.91,,,,HHH,-1.32933,0.175299,0.000268557,0.664183 Pab1_V198V,Pab1_198,Pab1,Pab1,P04147,,YES,198,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.113,-1.113,,,0.008,E,B,0.61,0.91,,,,HHH,-1.32933,0.175299,0.000268557,0.835076 Pab1_V198W,Pab1_198,Pab1,Pab1,P04147,,YES,198,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.113,-5.14,4.027,,0.008,E,B,0.61,0.91,,,,HHH,-1.32933,0.175299,0.000268557,0.670508 Pab1_V198Y,Pab1_198,Pab1,Pab1,P04147,,YES,198,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.113,-3.755,2.642,,0.008,E,B,0.61,0.91,,,,HHH,-1.32933,0.175299,0.000268557,0.657905 Pab1_Y143M,Pab1_143,Pab1,Pab1,P04147,,YES,143,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-1.961,-4.48,2.519,,0.409,H,A,,0.3,,,,HHA,-1.39633,0.175299,0.00160364,0.772878 Pab1_Y143Y,Pab1_143,Pab1,Pab1,P04147,,YES,143,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-1.961,-1.961,,,0.409,H,A,,0.3,,,,HHA,-1.39633,0.175299,0.00160364,0.812885 Pab1_Y197M,Pab1_197,Pab1,Pab1,P04147,,YES,197,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-1.345,-4.298,2.953,,,,,,,0.891,,80.42,HHH,-1.41767,0.175299,0.00302474,0.784756 Pab1_Y197Y,Pab1_197,Pab1,Pab1,P04147,,YES,197,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-1.345,-1.345,,,,,,,,0.891,,80.42,HHH,-1.41767,0.175299,0.00302474,0.786506 PSD95pdz3_A343A,PSD95pdz3_343,PSD95pdz3,PSD95pdz3,P31016,,YES,343,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.307,-1.307,,5.585,,,,,14.728,,,,HHO,-1.22067,0.0758425,0.000798084,0.934299 PSD95pdz3_A347A,PSD95pdz3_347,PSD95pdz3,PSD95pdz3,P31016,,YES,347,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.307,-1.307,,4.89689,,,,,15.176,,,,OHA,-1.269,0.0758425,0.00074525,0.934299 PSD95pdz3_A370A,PSD95pdz3_370,PSD95pdz3,PSD95pdz3,P31016,,YES,370,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.307,-1.307,,5.22304,,,,,17.284,,,,PHP,-1.57967,0.0758425,0.000429106,0.914223 PSD95pdz3_A375A,PSD95pdz3_375,PSD95pdz3,PSD95pdz3,P31016,,YES,375,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.307,-1.307,,5.05512,,,,,13.888,,,,PHH,-1.43767,0.0758425,0.000356809,0.930037 PSD95pdz3_A376A,PSD95pdz3_376,PSD95pdz3,PSD95pdz3,P31016,,YES,376,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.307,-1.307,,4.72134,,,,,17.108,,,,HHH,-1.49567,0.0758425,0.000341232,0.912465 PSD95pdz3_A378A,PSD95pdz3_378,PSD95pdz3,PSD95pdz3,P31016,,YES,378,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.307,-1.307,,4.86582,,,,,14.576,,,,HHH,-1.509,0.0758425,0.000313169,0.928928 PSD95pdz3_A382A,PSD95pdz3_382,PSD95pdz3,PSD95pdz3,P31016,,YES,382,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.307,-1.307,,5.30282,,,,,22.472,,,,PHO,-1.24167,0.0758425,0.000249256,0.921121 PSD95pdz3_A390A,PSD95pdz3_390,PSD95pdz3,PSD95pdz3,P31016,,YES,390,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.307,-1.307,,5.03823,,,,,12.46,,,,HHP,-1.54467,0.0758425,0.00104603,0.871212 PSD95pdz3_D332D,PSD95pdz3_332,PSD95pdz3,PSD95pdz3,P31016,,YES,332,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.264,-1.264,,6.09878,,,,,48.762,,,,AAO,-1.22533,0.0758425,0.000937818,0.810558 PSD95pdz3_D348D,PSD95pdz3_348,PSD95pdz3,PSD95pdz3,P31016,,YES,348,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.264,-1.264,,5.02473,,,,,16.8925,,,,HAH,-1.306,0.0758425,0.000731866,0.793823 PSD95pdz3_D357D,PSD95pdz3_357,PSD95pdz3,PSD95pdz3,P31016,,YES,357,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.264,-1.264,,5.22306,,,,,10.975,,,,OAP,-1.32367,0.0758425,0.000609015,0.820863 PSD95pdz3_D366D,PSD95pdz3_366,PSD95pdz3,PSD95pdz3,P31016,,YES,366,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.264,-1.264,,5.55684,,,,,20.2375,,,,HAH,-1.401,0.0758425,0.000481272,0.804959 PSD95pdz3_E331E,PSD95pdz3_331,PSD95pdz3,PSD95pdz3,P31016,,YES,331,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.404,-1.404,,5.86289,,,,,51.8889,,,,OAA,-1.22533,0.0758425,0.000950134,0.666703 PSD95pdz3_E334E,PSD95pdz3_334,PSD95pdz3,PSD95pdz3,P31016,,YES,334,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.404,-1.404,,5.60175,,,,,53.09,,,,OAO,-1.14,0.0758425,0.000912998,0.815902 PSD95pdz3_E352E,PSD95pdz3_352,PSD95pdz3,PSD95pdz3,P31016,,YES,352,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.587,-1.587,,5.49659,,,,,24.2,2.525,,86.88,OAH,-1.314,0.0758425,0.000892231,0.785306 PSD95pdz3_E373E,PSD95pdz3_373,PSD95pdz3,PSD95pdz3,P31016,,YES,373,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.404,-1.404,,5.79743,,,,,27.9833,,,,BAP,-1.57667,0.0758425,0.000387698,0.803715 PSD95pdz3_F325F,PSD95pdz3_325,PSD95pdz3,PSD95pdz3,P31016,,YES,325,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.524,-1.524,,5.50654,,,,,12.7236,,,,OHP,-1.314,0.0758425,0.00102273,0.837234 PSD95pdz3_F337F,PSD95pdz3_337,PSD95pdz3,PSD95pdz3,P31016,,YES,337,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.524,-1.524,,5.22838,,,,,13.4936,,,,HHH,-1.59467,0.0758425,0.000875287,0.906242 PSD95pdz3_F340F,PSD95pdz3_340,PSD95pdz3,PSD95pdz3,P31016,,YES,340,F,F,FF,Hydrophobic,Hydrophobic,3.32051,3.32051,0,0,165,165,0,189.9,189.9,0,-1.524,-1.524,,5.79283,,,,,11.8045,,,,PHH,-1.55767,0.0758425,0.000836987,0.907661 PSD95pdz3_G319G,PSD95pdz3_319,PSD95pdz3,PSD95pdz3,P31016,,YES,319,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.008,-1.008,,4.95387,,,,,18.8725,,,,BOP,-1.36967,0.0758425,0.00109317,0.896342 PSD95pdz3_G322G,PSD95pdz3_322,PSD95pdz3,PSD95pdz3,P31016,,YES,322,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.008,-1.008,,5.24791,,,,,16.3275,,,,POH,-1.24867,0.0758425,0.00105821,0.859754 PSD95pdz3_G324G,PSD95pdz3_324,PSD95pdz3,PSD95pdz3,P31016,,YES,324,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.008,-1.008,,4.98881,,,,,10.4525,,,,HOH,-1.293,0.0758425,0.00103462,0.87849 PSD95pdz3_G329G,PSD95pdz3_329,PSD95pdz3,PSD95pdz3,P31016,,YES,329,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.008,-1.008,,4.7671,,,,,19.7075,,,,HOO,-1.16033,0.0758425,0.000974577,0.781444 PSD95pdz3_G330G,PSD95pdz3_330,PSD95pdz3,PSD95pdz3,P31016,,YES,330,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.008,-1.008,,4.68351,,,,,31.405,,,,OOA,-1.14,0.0758425,0.000962386,0.779901 PSD95pdz3_G333G,PSD95pdz3_333,PSD95pdz3,PSD95pdz3,P31016,,YES,333,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.008,-1.008,,5.09445,,,,,48.755,,,,AOA,-1.22533,0.0758425,0.00092544,0.935009 PSD95pdz3_G335G,PSD95pdz3_335,PSD95pdz3,PSD95pdz3,P31016,,YES,335,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.008,-1.008,,4.76223,,,,,22.4225,,,,AOH,-1.34733,0.0758425,0.000900493,0.936392 PSD95pdz3_G344G,PSD95pdz3_344,PSD95pdz3,PSD95pdz3,P31016,,YES,344,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.008,-1.008,,4.83855,,,,,14.06,,,,HOO,-1.10767,0.0758425,0.00078498,0.933232 PSD95pdz3_G345G,PSD95pdz3_345,PSD95pdz3,PSD95pdz3,P31016,,YES,345,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.008,-1.008,,4.32868,,,,,13.165,,,,OOO,-1.084,0.0758425,0.000771806,0.933548 PSD95pdz3_G351G,PSD95pdz3_351,PSD95pdz3,PSD95pdz3,P31016,,YES,351,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.008,-1.008,,5.44798,,,,,20.7625,,,,POA,-1.37133,0.0758425,0.000691282,0.923185 PSD95pdz3_G356G,PSD95pdz3_356,PSD95pdz3,PSD95pdz3,P31016,,YES,356,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.008,-1.008,,4.8656,,,,,11.9575,,,,BOA,-1.22933,0.0758425,0.000623061,0.930264 PSD95pdz3_G364G,PSD95pdz3_364,PSD95pdz3,PSD95pdz3,P31016,,YES,364,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.008,-1.008,,5.53299,,,,,21.28,,,,POH,-1.33667,0.0758425,0.00050942,0.918221 PSD95pdz3_G383G,PSD95pdz3_383,PSD95pdz3,PSD95pdz3,P31016,,YES,383,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-1.008,-1.008,,5.17213,,,,,20.5325,,,,HOP,-1.338,0.0758425,0.000233044,0.9189 PSD95pdz3_H317H,PSD95pdz3_317,PSD95pdz3,PSD95pdz3,P31016,,YES,317,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-1.627,-1.627,,6.19713,,,,,25.885,,,,HBB,-1.613,0.0758425,0.00111619,0.847948 PSD95pdz3_H372H,PSD95pdz3_372,PSD95pdz3,PSD95pdz3,P31016,,YES,372,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-1.627,-1.627,,5.5607,,,,,17.008,,,,PBA,-1.63033,0.0758425,0.00040301,0.797197 PSD95pdz3_I314I,PSD95pdz3_314,PSD95pdz3,PSD95pdz3,P31016,,YES,314,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.628,-1.628,,5.39919,,,,,15.7775,0.397,,81.35,BHH,-1.61167,0.0758425,0.0012606,0.89305 PSD95pdz3_I316I,PSD95pdz3_316,PSD95pdz3,PSD95pdz3,P31016,,YES,316,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.63,-1.63,,5.46166,,,,,19.005,,,,HHB,-1.62733,0.0758425,0.00112762,0.825951 PSD95pdz3_I327I,PSD95pdz3_327,PSD95pdz3,PSD95pdz3,P31016,,YES,327,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.63,-1.63,,5.7413,,,,,14.0388,,,,PHH,-1.50167,0.0758425,0.000998774,0.724473 PSD95pdz3_I336I,PSD95pdz3_336,PSD95pdz3,PSD95pdz3,P31016,,YES,336,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.63,-1.63,,5.11321,,,,,13.6363,,,,OHH,-1.38733,0.0758425,0.000887923,0.823685 PSD95pdz3_I338I,PSD95pdz3_338,PSD95pdz3,PSD95pdz3,P31016,,YES,338,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.63,-1.63,,5.45113,,,,,13.0087,,,,HHP,-1.55767,0.0758425,0.000862587,0.823985 PSD95pdz3_I341I,PSD95pdz3_341,PSD95pdz3,PSD95pdz3,P31016,,YES,341,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.63,-1.63,,5.73946,,,,,10.3187,,,,HHH,-1.50033,0.0758425,0.000824087,0.830752 PSD95pdz3_I359I,PSD95pdz3_359,PSD95pdz3,PSD95pdz3,P31016,,YES,359,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.63,-1.63,,5.35151,,,,,14.8012,,,,PHH,-1.58667,0.0758425,0.000580694,0.807374 PSD95pdz3_I377I,PSD95pdz3_377,PSD95pdz3,PSD95pdz3,P31016,,YES,377,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.873,-1.873,,4.9532,,,,,19.185,2.364,,87.71,HHH,-1.49567,0.0758425,0.000795475,0.786768 PSD95pdz3_I388I,PSD95pdz3_388,PSD95pdz3,PSD95pdz3,P31016,,YES,388,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.63,-1.63,,5.17282,,,,,16.0025,,,,PHH,-1.54967,0.0758425,0.000151216,0.790321 PSD95pdz3_I389I,PSD95pdz3_389,PSD95pdz3,PSD95pdz3,P31016,,YES,389,I,I,II,Hydrophobic,Hydrophobic,6.02,6.02,0,0,131,131,0,166.7,166.7,0,-1.628,-1.628,,5.15116,,,,,14.8038,1.498,,87.71,HHH,-1.52167,0.0758425,0.00148097,0.885723 PSD95pdz3_K355K,PSD95pdz3_355,PSD95pdz3,PSD95pdz3,P31016,,YES,355,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.416,-1.416,,5.56865,,,,,17.2556,,,,BBO,-1.33533,0.0758425,0.00063703,0.885208 PSD95pdz3_K380K,PSD95pdz3_380,PSD95pdz3,PSD95pdz3,P31016,,YES,380,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.416,-1.416,,5.87979,,,,,19.6722,,,,HBP,-1.391,0.0758425,0.000281399,0.891008 PSD95pdz3_K393K,PSD95pdz3_393,PSD95pdz3,PSD95pdz3,P31016,,YES,393,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.416,-1.416,,5.42682,,,,,22.0122,,,,HBO,-1.4265,0.0758425,0.000879298,0.905876 PSD95pdz3_L323L,PSD95pdz3_323,PSD95pdz3,PSD95pdz3,P31016,,YES,323,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.347,-1.347,,5.12397,,,,,13.8825,,,,OHO,-1.121,0.0758425,0.00104644,0.864638 PSD95pdz3_L342L,PSD95pdz3_342,PSD95pdz3,PSD95pdz3,P31016,,YES,342,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.347,-1.347,,5.03015,,,,,12.0762,,,,HHH,-1.428,0.0758425,0.00081112,0.932294 PSD95pdz3_L349L,PSD95pdz3_349,PSD95pdz3,PSD95pdz3,P31016,,YES,349,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.347,-1.347,,5.14696,,,,,24.6438,,,,AHP,-1.37667,0.0758425,0.00071841,0.914875 PSD95pdz3_L353L,PSD95pdz3_353,PSD95pdz3,PSD95pdz3,P31016,,YES,353,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.347,-1.347,,5.81136,,,,,17.3525,,,,AHB,-1.50533,0.0758425,0.000664742,0.908444 PSD95pdz3_L360L,PSD95pdz3_360,PSD95pdz3,PSD95pdz3,P31016,,YES,360,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.431,-1.431,,5.09284,,,,,14.2425,1.419,,86.88,HHP,-1.52667,0.0758425,0.000770471,0.92788 PSD95pdz3_L367L,PSD95pdz3_367,PSD95pdz3,PSD95pdz3,P31016,,YES,367,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.347,-1.347,,5.47696,,,,,17.0063,,,,AHB,-1.39767,0.0758425,0.000466436,0.902441 PSD95pdz3_L379L,PSD95pdz3_379,PSD95pdz3,PSD95pdz3,P31016,,YES,379,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.347,-1.347,,5.37777,,,,,16.8762,,,,HHB,-1.35667,0.0758425,0.00029733,0.90125 PSD95pdz3_N326N,PSD95pdz3_326,PSD95pdz3,PSD95pdz3,P31016,,YES,326,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-1.41,-1.41,,5.52537,,,,,19.0688,,,,HPH,-1.52133,0.0758425,0.00101078,0.848707 PSD95pdz3_N363N,PSD95pdz3_363,PSD95pdz3,PSD95pdz3,P31016,,YES,363,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-1.41,-1.41,,5.23349,,,,,20.7037,,,,HPO,-1.29433,0.0758425,0.000524014,0.895172 PSD95pdz3_N369N,PSD95pdz3_369,PSD95pdz3,PSD95pdz3,P31016,,YES,369,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-1.572,-1.572,,5.91569,,,,,24.1262,0.44,,87.71,BPH,-1.487,0.0758425,0.000608412,0.892671 PSD95pdz3_N381N,PSD95pdz3_381,PSD95pdz3,PSD95pdz3,P31016,,YES,381,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-1.41,-1.41,,5.66057,,,,,28.2162,,,,BPH,-1.37767,0.0758425,0.000265374,0.894468 PSD95pdz3_P311P,PSD95pdz3_311,PSD95pdz3,PSD95pdz3,P31016,,YES,311,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.236,-1.236,,5.76649,,,,,14.78,,,,OOB,-1.409,0.0758425,0.0030796,0.806299 PSD95pdz3_P346P,PSD95pdz3_346,PSD95pdz3,PSD95pdz3,P31016,,YES,346,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.236,-1.236,,5.02406,,,,,14.6629,,,,OOH,-1.18367,0.0758425,0.000758563,0.835339 PSD95pdz3_Q358Q,PSD95pdz3_358,PSD95pdz3,PSD95pdz3,P31016,,YES,358,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-1.699,-1.699,,5.21282,,,,,14.8844,,,,APH,-1.531,0.0758425,0.000594893,0.82834 PSD95pdz3_Q374Q,PSD95pdz3_374,PSD95pdz3,PSD95pdz3,P31016,,YES,374,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-1.699,-1.699,,5.38825,,,,,17.3289,,,,APH,-1.47,0.0758425,0.000372298,0.773602 PSD95pdz3_Q384Q,PSD95pdz3_384,PSD95pdz3,PSD95pdz3,P31016,,YES,384,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-1.699,-1.699,,5.49339,,,,,23.54,,,,OPP,-1.41333,0.0758425,0.000216736,0.798295 PSD95pdz3_Q391Q,PSD95pdz3_391,PSD95pdz3,PSD95pdz3,P31016,,YES,391,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-1.699,-1.699,,5.50275,,,,,12.6589,,,,HPH,-1.481,0.0758425,0.000990786,0.716215 PSD95pdz3_R312R,PSD95pdz3_312,PSD95pdz3,PSD95pdz3,P31016,,YES,312,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.582,-1.582,,5.76826,,,,,12.2409,,,,OBB,-1.46667,0.0758425,0.00196255,0.864221 PSD95pdz3_R313R,PSD95pdz3_313,PSD95pdz3,PSD95pdz3,P31016,,YES,313,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.582,-1.582,,6.63563,,,,,18.3955,,,,BBH,-1.59733,0.0758425,0.000840067,0.872558 PSD95pdz3_R318R,PSD95pdz3_318,PSD95pdz3,PSD95pdz3,P31016,,YES,318,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.582,-1.582,,4.94876,,,,,17.5609,,,,BBO,-1.40567,0.0758425,0.00110471,0.862918 PSD95pdz3_R354R,PSD95pdz3_354,PSD95pdz3,PSD95pdz3,P31016,,YES,354,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.582,-1.582,,6.21887,,,,,23.7791,,,,HBB,-1.44833,0.0758425,0.000650924,0.867075 PSD95pdz3_R368R,PSD95pdz3_368,PSD95pdz3,PSD95pdz3,P31016,,YES,368,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.582,-1.582,,6.13355,,,,,18.1818,,,,HBP,-1.50033,0.0758425,0.000451517,0.857377 PSD95pdz3_S320S,PSD95pdz3_320,PSD95pdz3,PSD95pdz3,P31016,,YES,320,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.519,-1.519,,5.81757,,,,,21.4517,,,,OPP,-1.306,0.0758425,0.00108158,0.892587 PSD95pdz3_S339S,PSD95pdz3_339,PSD95pdz3,PSD95pdz3,P31016,,YES,339,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.519,-1.519,,5.34493,,,,,12.2167,,,,HPH,-1.55767,0.0758425,0.00084982,0.940498 PSD95pdz3_S350S,PSD95pdz3_350,PSD95pdz3,PSD95pdz3,P31016,,YES,350,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.519,-1.519,,4.97629,,,,,25.01,,,,HPO,-1.29133,0.0758425,0.000704883,0.918491 PSD95pdz3_S361S,PSD95pdz3_361,PSD95pdz3,PSD95pdz3,P31016,,YES,361,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.519,-1.519,,4.8722,,,,,16.4533,,,,HPH,-1.47167,0.0758425,0.00055296,0.906392 PSD95pdz3_S371S,PSD95pdz3_371,PSD95pdz3,PSD95pdz3,P31016,,YES,371,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.86,-1.86,,5.19744,,,,,17.1117,3.854,,87.71,HPB,-1.598,0.0758425,0.000847873,0.820543 PSD95pdz3_T321T,PSD95pdz3_321,PSD95pdz3,PSD95pdz3,P31016,,YES,321,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.391,-1.391,,5.19953,,,,,20.3371,,,,PPO,-1.306,0.0758425,0.00106992,0.875832 PSD95pdz3_T385T,PSD95pdz3_385,PSD95pdz3,PSD95pdz3,P31016,,YES,385,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.533,-1.533,,5.57157,,,,,23.6871,4.527,,87.71,PPH,-1.56567,0.0758425,0.000545119,0.910366 PSD95pdz3_T387T,PSD95pdz3_387,PSD95pdz3,PSD95pdz3,P31016,,YES,387,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.391,-1.391,,5.20757,,,,,18.8043,,,,HPH,-1.49533,0.0758425,0.000167911,0.918347 PSD95pdz3_V315V,PSD95pdz3_315,PSD95pdz3,PSD95pdz3,P31016,,YES,315,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.625,-1.625,,5.52024,,,,,18.4557,4.054,,81.35,HHH,-1.62767,0.0758425,0.00153536,0.892149 PSD95pdz3_V328V,PSD95pdz3_328,PSD95pdz3,PSD95pdz3,P31016,,YES,328,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.465,-1.465,,5.28275,,,,,16.8775,,,,HHO,-1.36767,0.0758425,0.000986706,0.77126 PSD95pdz3_V362V,PSD95pdz3_362,PSD95pdz3,PSD95pdz3,P31016,,YES,362,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.465,-1.465,,4.99436,,,,,19.6443,,,,PHP,-1.46467,0.0758425,0.000538527,0.918362 PSD95pdz3_V365V,PSD95pdz3_365,PSD95pdz3,PSD95pdz3,P31016,,YES,365,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.592,-1.592,,5.03791,,,,,18.9657,2.364,,81.35,OHA,-1.288,0.0758425,0.000649764,0.898968 PSD95pdz3_V386V,PSD95pdz3_386,PSD95pdz3,PSD95pdz3,P31016,,YES,386,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.465,-1.465,,5.18836,,,,,17.5429,,,,PHP,-1.463,0.0758425,0.000184509,0.915034 PSD95pdz3_Y392Y,PSD95pdz3_392,PSD95pdz3,PSD95pdz3,P31016,,YES,392,Y,Y,YY,Hydrophobic,Hydrophobic,5.66,5.66,0,0,181,181,0,193.6,193.6,0,-1.437,-1.437,,5.20337,,,,,11.725,,,,PHB,-1.51733,0.0758425,0.000935211,0.927439 Ubiquitin_D24E,Ubiquitin_24,Uba1,Ubiquitin,P0CG48,,YES,24,D,E,DE,negativeCharge,negativeCharge,5.0516,3.22,-1.8316,45,133,147,14,111.1,138.4,27.3,,-2.244,0.292,,,,,,,,,,HAP,,0.205827,0.0066591,0.799237 Ubiquitin_D32W,Ubiquitin_32,Uba1,Ubiquitin,P0CG48,,YES,32,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.451,-5.33,3.879,4.96502,0.835,H,A,,1.4,,,,PAB,-1.47067,0.205827,0.000758819,0.712996 Ubiquitin_D39T,Ubiquitin_39,Uba1,Ubiquitin,P0CG48,,YES,39,D,T,DT,negativeCharge,Polar,5.0516,5.6,0.5484,85,133,119,-14,111.1,116.1,5,-1.792,-3.54,1.748,5.1607,0.433,G,A,,0.55,,,,OAP,-1.754,0.205827,0.00071409,0.802201 Ubiquitin_D58P,Ubiquitin_58,Uba1,Ubiquitin,P0CG48,,YES,58,D,P,DP,negativeCharge,Special,5.0516,6.3,1.2484,108,133,115,-18,111.1,112.7,1.6,-1.622,-2.919,1.297,5.06391,0.457,G,A,,-0.54,,,,PAH,-1.60267,0.205827,0.000639847,0.693053 Ubiquitin_E34W,Ubiquitin_34,Uba1,Ubiquitin,P0CG48,,YES,34,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.294,-5.377,4.083,5.02178,0.406,H,A,1.62,0.6,1.295,,35.62,BAO,-1.24933,0.205827,0.000686048,0.728207 Ubiquitin_F45P,Ubiquitin_45,Uba1,Ubiquitin,P0CG48,,YES,45,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.322,-4.233,2.911,4.80693,0.26,E,B,1.62,-0.99,1.531,,53.87,HHH,-1.55267,0.205827,0.000470401,0.487654 Ubiquitin_F4E,Ubiquitin_4,Uba1,Ubiquitin,P0CG48,,YES,4,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.534,-3.674,2.14,4.77459,0.059,E,B,,-0.46,,,,HHH,-1.504,0.205827,0.000805043,0.50325 Ubiquitin_F4K,Ubiquitin_4,Uba1,Ubiquitin,P0CG48,,YES,4,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.534,-3.703,2.169,4.77459,0.059,E,B,,-0.46,,,,HHH,-1.504,0.205827,0.000805043,0.495659 Ubiquitin_F4R,Ubiquitin_4,Uba1,Ubiquitin,P0CG48,,YES,4,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.534,-3.97,2.436,4.77459,0.059,E,B,,-0.46,,,,HHH,-1.504,0.205827,0.000805043,0.491306 Ubiquitin_F4V,Ubiquitin_4,Uba1,Ubiquitin,P0CG48,,YES,4,F,V,FV,Hydrophobic,Hydrophobic,3.32051,5.60847,2.28795,50,165,117,-48,189.9,140,-49.9,-1.534,-3.361,1.827,4.77459,0.059,E,B,,-0.46,,,,HHH,-1.504,0.205827,0.000805043,0.537984 Ubiquitin_G10F,Ubiquitin_10,Uba1,Ubiquitin,P0CG48,,YES,10,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.396,-4.141,2.745,5.29806,0.115,S,l,,0.2,,,,POB,-1.38633,0.205827,0.000748953,0.54094 Ubiquitin_G10I,Ubiquitin_10,Uba1,Ubiquitin,P0CG48,,YES,10,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.396,-3.901,2.505,5.29806,0.115,S,l,,0.2,,,,POB,-1.38633,0.205827,0.000748953,0.528909 Ubiquitin_G10M,Ubiquitin_10,Uba1,Ubiquitin,P0CG48,,YES,10,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.396,-4.752,3.356,5.29806,0.115,S,l,,0.2,,,,POB,-1.38633,0.205827,0.000748953,0.559976 Ubiquitin_G10V,Ubiquitin_10,Uba1,Ubiquitin,P0CG48,,YES,10,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.396,-2.792,1.396,5.29806,0.115,S,l,,0.2,,,,POB,-1.38633,0.205827,0.000748953,0.518422 Ubiquitin_G10W,Ubiquitin_10,Uba1,Ubiquitin,P0CG48,,YES,10,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.396,-5.219,3.823,5.29806,0.115,S,l,,0.2,,,,POB,-1.38633,0.205827,0.000748953,0.552354 Ubiquitin_G10Y,Ubiquitin_10,Uba1,Ubiquitin,P0CG48,,YES,10,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.396,-2.983,1.587,5.29806,0.115,S,l,,0.2,,,,POB,-1.38633,0.205827,0.000748953,0.521872 Ubiquitin_G47C,Ubiquitin_47,Uba1,Ubiquitin,P0CG48,,YES,47,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.423,-3.184,1.761,5.24944,0.057,T,l,,-1.21,,,,HOB,-1.543,0.205827,0.000471587,0.639062 Ubiquitin_G47D,Ubiquitin_47,Uba1,Ubiquitin,P0CG48,,YES,47,G,D,GD,Special,negativeCharge,3.29388,5.0516,1.75772,94,75,133,58,60.1,111.1,51,-1.423,-2.668,1.245,5.24944,0.057,T,l,,-1.21,,,,HOB,-1.543,0.205827,0.000471587,0.581558 Ubiquitin_G47F,Ubiquitin_47,Uba1,Ubiquitin,P0CG48,,YES,47,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.423,-4.36,2.937,5.24944,0.057,T,l,,-1.21,,,,HOB,-1.543,0.205827,0.000471587,0.625903 Ubiquitin_G47H,Ubiquitin_47,Uba1,Ubiquitin,P0CG48,,YES,47,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-1.423,-4.586,3.163,5.24944,0.057,T,l,,-1.21,,,,HOB,-1.543,0.205827,0.000471587,0.639063 Ubiquitin_G47I,Ubiquitin_47,Uba1,Ubiquitin,P0CG48,,YES,47,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.423,-4.105,2.682,5.24944,0.057,T,l,,-1.21,,,,HOB,-1.543,0.205827,0.000471587,0.61288 Ubiquitin_G47K,Ubiquitin_47,Uba1,Ubiquitin,P0CG48,,YES,47,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.423,-3.472,2.049,5.24944,0.057,T,l,,-1.21,,,,HOB,-1.543,0.205827,0.000471587,0.612989 Ubiquitin_G47L,Ubiquitin_47,Uba1,Ubiquitin,P0CG48,,YES,47,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.423,-3.656,2.233,5.24944,0.057,T,l,,-1.21,,,,HOB,-1.543,0.205827,0.000471587,0.612646 Ubiquitin_G47M,Ubiquitin_47,Uba1,Ubiquitin,P0CG48,,YES,47,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.423,-4.8,3.377,5.24944,0.057,T,l,,-1.21,,,,HOB,-1.543,0.205827,0.000471587,0.641734 Ubiquitin_G47N,Ubiquitin_47,Uba1,Ubiquitin,P0CG48,,YES,47,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.423,-2.747,1.324,5.24944,0.057,T,l,,-1.21,,,,HOB,-1.543,0.205827,0.000471587,0.635141 Ubiquitin_G47P,Ubiquitin_47,Uba1,Ubiquitin,P0CG48,,YES,47,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-1.423,-3.918,2.495,5.24944,0.057,T,l,,-1.21,,,,HOB,-1.543,0.205827,0.000471587,0.561051 Ubiquitin_G47R,Ubiquitin_47,Uba1,Ubiquitin,P0CG48,,YES,47,G,R,GR,Special,PositiveCharge,3.29388,6.34148,3.0476,125,75,174,99,60.1,173.4,113.3,-1.423,-2.888,1.465,5.24944,0.057,T,l,,-1.21,,,,HOB,-1.543,0.205827,0.000471587,0.62634 Ubiquitin_G47T,Ubiquitin_47,Uba1,Ubiquitin,P0CG48,,YES,47,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.423,-2.739,1.316,5.24944,0.057,T,l,,-1.21,,,,HOB,-1.543,0.205827,0.000471587,0.642154 Ubiquitin_G47V,Ubiquitin_47,Uba1,Ubiquitin,P0CG48,,YES,47,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.423,-3.711,2.288,5.24944,0.057,T,l,,-1.21,,,,HOB,-1.543,0.205827,0.000471587,0.618697 Ubiquitin_G47W,Ubiquitin_47,Uba1,Ubiquitin,P0CG48,,YES,47,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.423,-5.332,3.909,5.24944,0.057,T,l,,-1.21,,,,HOB,-1.543,0.205827,0.000471587,0.636378 Ubiquitin_G47Y,Ubiquitin_47,Uba1,Ubiquitin,P0CG48,,YES,47,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.423,-4.358,2.935,5.24944,0.057,T,l,,-1.21,,,,HOB,-1.543,0.205827,0.000471587,0.62485 Ubiquitin_G75C,Ubiquitin_75,Uba1,Ubiquitin,P0CG48,,YES,75,G,C,GC,Special,Special,3.29388,5.07,1.77612,159,75,121,46,60.1,108.5,48.4,-1.613,-2.992,1.379,5.44099,0.552,T,A,0.73,0.9,4.017,,34.31,BOO,-1.66767,0.205827,0.000712673,0.390698 Ubiquitin_G75S,Ubiquitin_75,Uba1,Ubiquitin,P0CG48,,YES,75,G,S,GS,Special,Polar,3.29388,5.68,2.38612,56,75,105,30,60.1,89,28.9,-1.613,-2.413,0.8,5.44099,0.552,T,A,0.73,0.9,4.017,,34.31,BOO,-1.66767,0.205827,0.000712673,0.421416 Ubiquitin_G75T,Ubiquitin_75,Uba1,Ubiquitin,P0CG48,,YES,75,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-1.613,-2.639,1.026,5.44099,0.552,T,A,0.73,0.9,4.017,,34.31,BOO,-1.66767,0.205827,0.000712673,0.423275 Ubiquitin_G75W,Ubiquitin_75,Uba1,Ubiquitin,P0CG48,,YES,75,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.613,-3.333,1.72,5.44099,0.552,T,A,0.73,0.9,4.017,,34.31,BOO,-1.66767,0.205827,0.000712673,0.396236 Ubiquitin_G76A,Ubiquitin_76,Uba1,Ubiquitin,P0CG48,,YES,76,G,A,GA,Special,Hydrophobic,3.29388,6,2.70612,60,75,89,14,60.1,88.6,28.5,-1.651,-2.642,0.991,5.7647,0.23,,B,0.12,0.08,9.665,9.665,34.31,OOO,-1.632,0.205827,0.000653872,0.42041 Ubiquitin_G76F,Ubiquitin_76,Uba1,Ubiquitin,P0CG48,,YES,76,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-1.651,-4.273,2.622,5.7647,0.23,,B,0.12,0.08,9.665,9.665,34.31,OOO,-1.632,0.205827,0.000653872,0.403589 Ubiquitin_G76I,Ubiquitin_76,Uba1,Ubiquitin,P0CG48,,YES,76,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.651,-3.099,1.448,5.7647,0.23,,B,0.12,0.08,9.665,9.665,34.31,OOO,-1.632,0.205827,0.000653872,0.419294 Ubiquitin_G76K,Ubiquitin_76,Uba1,Ubiquitin,P0CG48,,YES,76,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.651,-2.689,1.038,5.7647,0.23,,B,0.12,0.08,9.665,9.665,34.31,OOO,-1.632,0.205827,0.000653872,0.413267 Ubiquitin_G76L,Ubiquitin_76,Uba1,Ubiquitin,P0CG48,,YES,76,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.651,-3.545,1.894,5.7647,0.23,,B,0.12,0.08,9.665,9.665,34.31,OOO,-1.632,0.205827,0.000653872,0.413278 Ubiquitin_G76M,Ubiquitin_76,Uba1,Ubiquitin,P0CG48,,YES,76,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.651,-4.768,3.117,5.7647,0.23,,B,0.12,0.08,9.665,9.665,34.31,OOO,-1.632,0.205827,0.000653872,0.41807 Ubiquitin_G76N,Ubiquitin_76,Uba1,Ubiquitin,P0CG48,,YES,76,G,N,GN,Special,Polar,3.29388,5.47157,2.1777,80,75,132,57,60.1,114.1,54,-1.651,-2.95,1.299,5.7647,0.23,,B,0.12,0.08,9.665,9.665,34.31,OOO,-1.632,0.205827,0.000653872,0.457784 Ubiquitin_G76Q,Ubiquitin_76,Uba1,Ubiquitin,P0CG48,,YES,76,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.651,-4.012,2.361,5.7647,0.23,,B,0.12,0.08,9.665,9.665,34.31,OOO,-1.632,0.205827,0.000653872,0.439286 Ubiquitin_G76V,Ubiquitin_76,Uba1,Ubiquitin,P0CG48,,YES,76,G,V,GV,Special,Hydrophobic,3.29388,5.60847,2.31459,109,75,117,42,60.1,140,79.9,-1.651,-2.917,1.266,5.7647,0.23,,B,0.12,0.08,9.665,9.665,34.31,OOO,-1.632,0.205827,0.000653872,0.425224 Ubiquitin_G76W,Ubiquitin_76,Uba1,Ubiquitin,P0CG48,,YES,76,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.651,-3.4,1.749,5.7647,0.23,,B,0.12,0.08,9.665,9.665,34.31,OOO,-1.632,0.205827,0.000653872,0.413242 Ubiquitin_G76Y,Ubiquitin_76,Uba1,Ubiquitin,P0CG48,,YES,76,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.651,,,5.7647,0.23,,B,0.12,0.08,9.665,9.665,34.31,OOO,-1.632,0.205827,0.000653872,0.411296 Ubiquitin_H68K,Ubiquitin_68,Uba1,Ubiquitin,P0CG48,,YES,68,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-1.869,-3.712,1.843,4.81902,0.194,E,B,0.72,-1.02,21.325,21.325,65.11,HBH,-1.583,0.205827,0.000925438,0.550685 Ubiquitin_H68R,Ubiquitin_68,Uba1,Ubiquitin,P0CG48,,YES,68,H,R,HR,PositiveCharge,PositiveCharge,7.59,6.34148,-1.24852,29,155,174,19,153.2,173.4,20.2,-1.869,-3.932,2.063,4.81902,0.194,E,B,0.72,-1.02,21.325,21.325,65.11,HBH,-1.583,0.205827,0.000925438,0.553618 Ubiquitin_I13F,Ubiquitin_13,Uba1,Ubiquitin,P0CG48,,YES,13,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.554,-2.795,1.241,5.19411,0.038,E,B,,-0.2,,,,PHP,-1.48,0.205827,0.000716423,0.546683 Ubiquitin_I23D,Ubiquitin_23,Uba1,Ubiquitin,P0CG48,,YES,23,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.325,-3.938,2.613,4.67534,,H,A,0.01,-0.93,0.515,,52.12,PHA,-1.54033,0.205827,0.000621252,0.580231 Ubiquitin_I23K,Ubiquitin_23,Uba1,Ubiquitin,P0CG48,,YES,23,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.325,-3.836,2.511,4.67534,,H,A,0.01,-0.93,0.515,,52.12,PHA,-1.54033,0.205827,0.000621252,0.611917 Ubiquitin_I23Y,Ubiquitin_23,Uba1,Ubiquitin,P0CG48,,YES,23,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.325,-3.898,2.573,4.67534,,H,A,0.01,-0.93,0.515,,52.12,PHA,-1.54033,0.205827,0.000621252,0.566383 Ubiquitin_I30D,Ubiquitin_30,Uba1,Ubiquitin,P0CG48,,YES,30,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.205,-3.861,2.656,4.80264,,H,A,,-0.51,,,,BHP,-1.45133,0.205827,0.000720128,0.606783 Ubiquitin_I30E,Ubiquitin_30,Uba1,Ubiquitin,P0CG48,,YES,30,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.205,-3.786,2.581,4.80264,,H,A,,-0.51,,,,BHP,-1.45133,0.205827,0.000720128,0.622088 Ubiquitin_I30G,Ubiquitin_30,Uba1,Ubiquitin,P0CG48,,YES,30,I,G,IG,Hydrophobic,Special,6.02,3.29388,-2.72612,135,131,75,-56,166.7,60.1,-106.6,-1.205,-3.656,2.451,4.80264,,H,A,,-0.51,,,,BHP,-1.45133,0.205827,0.000720128,0.63663 Ubiquitin_I30H,Ubiquitin_30,Uba1,Ubiquitin,P0CG48,,YES,30,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.205,-4.868,3.663,4.80264,,H,A,,-0.51,,,,BHP,-1.45133,0.205827,0.000720128,0.640338 Ubiquitin_I30K,Ubiquitin_30,Uba1,Ubiquitin,P0CG48,,YES,30,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.205,-3.778,2.573,4.80264,,H,A,,-0.51,,,,BHP,-1.45133,0.205827,0.000720128,0.63279 Ubiquitin_I30N,Ubiquitin_30,Uba1,Ubiquitin,P0CG48,,YES,30,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.205,-3.995,2.79,4.80264,,H,A,,-0.51,,,,BHP,-1.45133,0.205827,0.000720128,0.630172 Ubiquitin_I30Q,Ubiquitin_30,Uba1,Ubiquitin,P0CG48,,YES,30,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.205,-4.221,3.016,4.80264,,H,A,,-0.51,,,,BHP,-1.45133,0.205827,0.000720128,0.638159 Ubiquitin_I30W,Ubiquitin_30,Uba1,Ubiquitin,P0CG48,,YES,30,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.205,-5.32,4.115,4.80264,,H,A,,-0.51,,,,BHP,-1.45133,0.205827,0.000720128,0.577427 Ubiquitin_I36D,Ubiquitin_36,Uba1,Ubiquitin,P0CG48,,YES,36,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.477,-3.733,2.256,5.1035,0.203,,B,0.27,-0.22,1.552,,30.8,OHO,-1.30767,0.205827,0.000630555,0.673544 Ubiquitin_I36E,Ubiquitin_36,Uba1,Ubiquitin,P0CG48,,YES,36,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.477,-3.699,2.222,5.1035,0.203,,B,0.27,-0.22,1.552,,30.8,OHO,-1.30767,0.205827,0.000630555,0.682479 Ubiquitin_I36F,Ubiquitin_36,Uba1,Ubiquitin,P0CG48,,YES,36,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.477,-3.86,2.383,5.1035,0.203,,B,0.27,-0.22,1.552,,30.8,OHO,-1.30767,0.205827,0.000630555,0.66714 Ubiquitin_I36K,Ubiquitin_36,Uba1,Ubiquitin,P0CG48,,YES,36,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.477,-3.698,2.221,5.1035,0.203,,B,0.27,-0.22,1.552,,30.8,OHO,-1.30767,0.205827,0.000630555,0.692042 Ubiquitin_I36N,Ubiquitin_36,Uba1,Ubiquitin,P0CG48,,YES,36,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.477,-2.772,1.295,5.1035,0.203,,B,0.27,-0.22,1.552,,30.8,OHO,-1.30767,0.205827,0.000630555,0.736632 Ubiquitin_I3D,Ubiquitin_3,Uba1,Ubiquitin,P0CG48,,YES,3,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.402,-3.946,2.544,4.80819,,E,B,,-0.78,,,,PHH,-1.54533,0.205827,0.000836911,0.426366 Ubiquitin_I3F,Ubiquitin_3,Uba1,Ubiquitin,P0CG48,,YES,3,I,F,IF,Hydrophobic,Hydrophobic,6.02,3.32051,-2.69949,21,131,165,34,166.7,189.9,23.2,-1.402,-3.641,2.239,4.80819,,E,B,,-0.78,,,,PHH,-1.54533,0.205827,0.000836911,0.495659 Ubiquitin_I3H,Ubiquitin_3,Uba1,Ubiquitin,P0CG48,,YES,3,I,H,IH,Hydrophobic,PositiveCharge,6.02,7.59,1.57,94,131,155,24,166.7,153.2,-13.5,-1.402,-4.749,3.347,4.80819,,E,B,,-0.78,,,,PHH,-1.54533,0.205827,0.000836911,0.493793 Ubiquitin_I3K,Ubiquitin_3,Uba1,Ubiquitin,P0CG48,,YES,3,I,K,IK,Hydrophobic,PositiveCharge,6.02,9.74,3.72,102,131,146,15,166.7,168.6,1.9,-1.402,-3.814,2.412,4.80819,,E,B,,-0.78,,,,PHH,-1.54533,0.205827,0.000836911,0.451996 Ubiquitin_I3P,Ubiquitin_3,Uba1,Ubiquitin,P0CG48,,YES,3,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.402,-4.068,2.666,4.80819,,E,B,,-0.78,,,,PHH,-1.54533,0.205827,0.000836911,0.406574 Ubiquitin_I3W,Ubiquitin_3,Uba1,Ubiquitin,P0CG48,,YES,3,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.402,-5.136,3.734,4.80819,,E,B,,-0.78,,,,PHH,-1.54533,0.205827,0.000836911,0.483706 Ubiquitin_I3Y,Ubiquitin_3,Uba1,Ubiquitin,P0CG48,,YES,3,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.402,-2.753,1.351,4.80819,,E,B,,-0.78,,,,PHH,-1.54533,0.205827,0.000836911,0.534332 Ubiquitin_I44P,Ubiquitin_44,Uba1,Ubiquitin,P0CG48,,YES,44,I,P,IP,Hydrophobic,Special,6.02,6.3,0.28,95,131,115,-16,166.7,112.7,-54,-1.566,-4.056,2.49,4.71256,,E,B,0.27,-1.17,5.26,,39.71,HHH,-1.38567,0.205827,0.000613305,0.56682 Ubiquitin_I61N,Ubiquitin_61,Uba1,Ubiquitin,P0CG48,,YES,61,I,N,IN,Hydrophobic,Polar,6.02,5.47157,-0.548425,149,131,132,1,166.7,114.1,-52.6,-1.514,-3.98,2.466,5.19922,0.038,,B,1,-0.76,1.953,,24.53,PHP,-1.70833,0.205827,0.000738268,0.630187 Ubiquitin_I61Y,Ubiquitin_61,Uba1,Ubiquitin,P0CG48,,YES,61,I,Y,IY,Hydrophobic,Hydrophobic,6.02,5.66,-0.36,33,131,181,50,166.7,193.6,26.9,-1.514,-4.143,2.629,5.19922,0.038,,B,1,-0.76,1.953,,24.53,PHP,-1.70833,0.205827,0.000738268,0.633668 Ubiquitin_K27D,Ubiquitin_27,Uba1,Ubiquitin,P0CG48,,YES,27,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.064,-3.495,2.431,4.77438,0.086,H,A,2.89,-0.74,2.662,,27.01,HBH,-1.42667,0.205827,0.000767556,0.584556 Ubiquitin_K27P,Ubiquitin_27,Uba1,Ubiquitin,P0CG48,,YES,27,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.064,-3.708,2.644,4.77438,0.086,H,A,2.89,-0.74,2.662,,27.01,HBH,-1.42667,0.205827,0.000767556,0.572069 Ubiquitin_K29D,Ubiquitin_29,Uba1,Ubiquitin,P0CG48,,YES,29,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.471,-2.738,1.267,4.74832,0.355,H,A,,-0.06,,,,HBH,-1.52367,0.205827,0.000900239,0.678724 Ubiquitin_K29E,Ubiquitin_29,Uba1,Ubiquitin,P0CG48,,YES,29,K,E,KE,PositiveCharge,negativeCharge,9.74,3.22,-6.52,56,146,147,1,168.6,138.4,-30.2,-1.471,-2.616,1.145,4.74832,0.355,H,A,,-0.06,,,,HBH,-1.52367,0.205827,0.000900239,0.672553 Ubiquitin_K29P,Ubiquitin_29,Uba1,Ubiquitin,P0CG48,,YES,29,K,P,KP,PositiveCharge,Special,9.74,6.3,-3.44,103,146,115,-31,168.6,112.7,-55.9,-1.471,-3.876,2.405,4.74832,0.355,H,A,,-0.06,,,,HBH,-1.52367,0.205827,0.000900239,0.552343 Ubiquitin_K6D,Ubiquitin_6,Uba1,Ubiquitin,P0CG48,,YES,6,K,D,KD,PositiveCharge,negativeCharge,9.74,5.0516,-4.6884,101,146,133,-13,168.6,111.1,-57.5,-1.093,-3.342,2.249,4.84211,0.35,E,B,1.82,-0.62,1.502,,71.82,HBP,-1.36133,0.205827,0.000784795,0.651133 Ubiquitin_L15K,Ubiquitin_15,Uba1,Ubiquitin,P0CG48,,YES,15,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.082,-3.743,2.661,5.14718,0.029,E,B,1.16,-0.53,0.936,,38.69,PHA,-1.40833,0.205827,0.000519738,0.444187 Ubiquitin_L43D,Ubiquitin_43,Uba1,Ubiquitin,P0CG48,,YES,43,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.269,-4.04,2.771,4.8799,,E,B,1.75,-1.17,10.246,10.246,53.87,BHH,-1.46867,0.205827,0.000572481,0.453415 Ubiquitin_L43E,Ubiquitin_43,Uba1,Ubiquitin,P0CG48,,YES,43,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.269,-3.822,2.553,4.8799,,E,B,1.75,-1.17,10.246,10.246,53.87,BHH,-1.46867,0.205827,0.000572481,0.476581 Ubiquitin_L43G,Ubiquitin_43,Uba1,Ubiquitin,P0CG48,,YES,43,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.269,-3.769,2.5,4.8799,,E,B,1.75,-1.17,10.246,10.246,53.87,BHH,-1.46867,0.205827,0.000572481,0.507259 Ubiquitin_L43H,Ubiquitin_43,Uba1,Ubiquitin,P0CG48,,YES,43,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.269,-4.879,3.61,4.8799,,E,B,1.75,-1.17,10.246,10.246,53.87,BHH,-1.46867,0.205827,0.000572481,0.514533 Ubiquitin_L43K,Ubiquitin_43,Uba1,Ubiquitin,P0CG48,,YES,43,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.269,-3.649,2.38,4.8799,,E,B,1.75,-1.17,10.246,10.246,53.87,BHH,-1.46867,0.205827,0.000572481,0.503411 Ubiquitin_L43N,Ubiquitin_43,Uba1,Ubiquitin,P0CG48,,YES,43,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.269,-4.044,2.775,4.8799,,E,B,1.75,-1.17,10.246,10.246,53.87,BHH,-1.46867,0.205827,0.000572481,0.506028 Ubiquitin_L43P,Ubiquitin_43,Uba1,Ubiquitin,P0CG48,,YES,43,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.269,-4.089,2.82,4.8799,,E,B,1.75,-1.17,10.246,10.246,53.87,BHH,-1.46867,0.205827,0.000572481,0.483603 Ubiquitin_L43Q,Ubiquitin_43,Uba1,Ubiquitin,P0CG48,,YES,43,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.269,-4.105,2.836,4.8799,,E,B,1.75,-1.17,10.246,10.246,53.87,BHH,-1.46867,0.205827,0.000572481,0.51376 Ubiquitin_L43S,Ubiquitin_43,Uba1,Ubiquitin,P0CG48,,YES,43,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.269,-3.584,2.315,4.8799,,E,B,1.75,-1.17,10.246,10.246,53.87,BHH,-1.46867,0.205827,0.000572481,0.538145 Ubiquitin_L43T,Ubiquitin_43,Uba1,Ubiquitin,P0CG48,,YES,43,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.269,-2.654,1.385,4.8799,,E,B,1.75,-1.17,10.246,10.246,53.87,BHH,-1.46867,0.205827,0.000572481,0.565736 Ubiquitin_L50D,Ubiquitin_50,Uba1,Ubiquitin,P0CG48,,YES,50,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.107,-3.939,2.832,5.19399,0.029,,B,,-0.92,,,,PHA,-1.52733,0.205827,0.000734242,0.493254 Ubiquitin_L50E,Ubiquitin_50,Uba1,Ubiquitin,P0CG48,,YES,50,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.107,-3.694,2.587,5.19399,0.029,,B,,-0.92,,,,PHA,-1.52733,0.205827,0.000734242,0.518816 Ubiquitin_L50F,Ubiquitin_50,Uba1,Ubiquitin,P0CG48,,YES,50,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.107,-3.745,2.638,5.19399,0.029,,B,,-0.92,,,,PHA,-1.52733,0.205827,0.000734242,0.536444 Ubiquitin_L50G,Ubiquitin_50,Uba1,Ubiquitin,P0CG48,,YES,50,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.107,-3.604,2.497,5.19399,0.029,,B,,-0.92,,,,PHA,-1.52733,0.205827,0.000734242,0.526248 Ubiquitin_L50H,Ubiquitin_50,Uba1,Ubiquitin,P0CG48,,YES,50,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.107,-4.746,3.639,5.19399,0.029,,B,,-0.92,,,,PHA,-1.52733,0.205827,0.000734242,0.575494 Ubiquitin_L50K,Ubiquitin_50,Uba1,Ubiquitin,P0CG48,,YES,50,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.107,-3.477,2.37,5.19399,0.029,,B,,-0.92,,,,PHA,-1.52733,0.205827,0.000734242,0.533514 Ubiquitin_L50N,Ubiquitin_50,Uba1,Ubiquitin,P0CG48,,YES,50,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.107,-3.883,2.776,5.19399,0.029,,B,,-0.92,,,,PHA,-1.52733,0.205827,0.000734242,0.543824 Ubiquitin_L50P,Ubiquitin_50,Uba1,Ubiquitin,P0CG48,,YES,50,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.107,-4.015,2.908,5.19399,0.029,,B,,-0.92,,,,PHA,-1.52733,0.205827,0.000734242,0.4855 Ubiquitin_L50Q,Ubiquitin_50,Uba1,Ubiquitin,P0CG48,,YES,50,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.107,-3.936,2.829,5.19399,0.029,,B,,-0.92,,,,PHA,-1.52733,0.205827,0.000734242,0.553829 Ubiquitin_L50R,Ubiquitin_50,Uba1,Ubiquitin,P0CG48,,YES,50,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.107,-2.693,1.586,5.19399,0.029,,B,,-0.92,,,,PHA,-1.52733,0.205827,0.000734242,0.595256 Ubiquitin_L50S,Ubiquitin_50,Uba1,Ubiquitin,P0CG48,,YES,50,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.107,-2.583,1.476,5.19399,0.029,,B,,-0.92,,,,PHA,-1.52733,0.205827,0.000734242,0.614128 Ubiquitin_L50W,Ubiquitin_50,Uba1,Ubiquitin,P0CG48,,YES,50,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.107,-5.14,4.033,5.19399,0.029,,B,,-0.92,,,,PHA,-1.52733,0.205827,0.000734242,0.57232 Ubiquitin_L50Y,Ubiquitin_50,Uba1,Ubiquitin,P0CG48,,YES,50,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.107,-4.01,2.903,5.19399,0.029,,B,,-0.92,,,,PHA,-1.52733,0.205827,0.000734242,0.544952 Ubiquitin_L56D,Ubiquitin_56,Uba1,Ubiquitin,P0CG48,,YES,56,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.324,-4.025,2.701,4.83362,,T,A,,-0.91,,,,PHP,-1.60067,0.205827,0.000459465,0.521083 Ubiquitin_L56E,Ubiquitin_56,Uba1,Ubiquitin,P0CG48,,YES,56,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.324,-3.843,2.519,4.83362,,T,A,,-0.91,,,,PHP,-1.60067,0.205827,0.000459465,0.539894 Ubiquitin_L56G,Ubiquitin_56,Uba1,Ubiquitin,P0CG48,,YES,56,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.324,-3.658,2.334,4.83362,,T,A,,-0.91,,,,PHP,-1.60067,0.205827,0.000459465,0.539001 Ubiquitin_L56H,Ubiquitin_56,Uba1,Ubiquitin,P0CG48,,YES,56,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.324,-4.894,3.57,4.83362,,T,A,,-0.91,,,,PHP,-1.60067,0.205827,0.000459465,0.567646 Ubiquitin_L56K,Ubiquitin_56,Uba1,Ubiquitin,P0CG48,,YES,56,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.324,-3.748,2.424,4.83362,,T,A,,-0.91,,,,PHP,-1.60067,0.205827,0.000459465,0.540834 Ubiquitin_L56N,Ubiquitin_56,Uba1,Ubiquitin,P0CG48,,YES,56,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.324,-4.09,2.766,4.83362,,T,A,,-0.91,,,,PHP,-1.60067,0.205827,0.000459465,0.549508 Ubiquitin_L56Q,Ubiquitin_56,Uba1,Ubiquitin,P0CG48,,YES,56,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.324,-4.167,2.843,4.83362,,T,A,,-0.91,,,,PHP,-1.60067,0.205827,0.000459465,0.555712 Ubiquitin_L56R,Ubiquitin_56,Uba1,Ubiquitin,P0CG48,,YES,56,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.324,-4.047,2.723,4.83362,,T,A,,-0.91,,,,PHP,-1.60067,0.205827,0.000459465,0.56236 Ubiquitin_L56S,Ubiquitin_56,Uba1,Ubiquitin,P0CG48,,YES,56,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.324,-2.765,1.441,4.83362,,T,A,,-0.91,,,,PHP,-1.60067,0.205827,0.000459465,0.594886 Ubiquitin_L56Y,Ubiquitin_56,Uba1,Ubiquitin,P0CG48,,YES,56,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.324,-3.968,2.644,4.83362,,T,A,,-0.91,,,,PHP,-1.60067,0.205827,0.000459465,0.554252 Ubiquitin_L67W,Ubiquitin_67,Uba1,Ubiquitin,P0CG48,,YES,67,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.435,-5.294,3.859,4.92156,,E,B,1.19,-1.02,6.371,6.371,30.8,PHB,-1.628,0.205827,0.000482727,0.526899 Ubiquitin_L69P,Ubiquitin_69,Uba1,Ubiquitin,P0CG48,,YES,69,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.445,-2.945,1.5,4.75624,0.051,E,B,2.89,-0.94,7.106,,34.31,BHH,-1.72933,0.205827,0.000919136,0.411836 Ubiquitin_L71A,Ubiquitin_71,Uba1,Ubiquitin,P0CG48,,YES,71,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.647,-2.671,1.024,5.02588,0.591,E,B,2.89,-0.69,4.365,,34.31,HHB,-1.85167,0.205827,0.000949314,0.552488 Ubiquitin_L71D,Ubiquitin_71,Uba1,Ubiquitin,P0CG48,,YES,71,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.647,-3.839,2.192,5.02588,0.591,E,B,2.89,-0.69,4.365,,34.31,HHB,-1.85167,0.205827,0.000949314,0.488347 Ubiquitin_L71E,Ubiquitin_71,Uba1,Ubiquitin,P0CG48,,YES,71,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.647,-2.933,1.286,5.02588,0.591,E,B,2.89,-0.69,4.365,,34.31,HHB,-1.85167,0.205827,0.000949314,0.525351 Ubiquitin_L71G,Ubiquitin_71,Uba1,Ubiquitin,P0CG48,,YES,71,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.647,-3.608,1.961,5.02588,0.591,E,B,2.89,-0.69,4.365,,34.31,HHB,-1.85167,0.205827,0.000949314,0.516717 Ubiquitin_L71N,Ubiquitin_71,Uba1,Ubiquitin,P0CG48,,YES,71,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.647,-3.02,1.373,5.02588,0.591,E,B,2.89,-0.69,4.365,,34.31,HHB,-1.85167,0.205827,0.000949314,0.543185 Ubiquitin_L71S,Ubiquitin_71,Uba1,Ubiquitin,P0CG48,,YES,71,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.647,-2.867,1.22,5.02588,0.591,E,B,2.89,-0.69,4.365,,34.31,HHB,-1.85167,0.205827,0.000949314,0.550083 Ubiquitin_L71T,Ubiquitin_71,Uba1,Ubiquitin,P0CG48,,YES,71,L,T,LT,Hydrophobic,Polar,9.7088,5.6,-4.1088,92,131,119,-12,166.7,116.1,-50.6,-1.647,-3.561,1.914,5.02588,0.591,E,B,2.89,-0.69,4.365,,34.31,HHB,-1.85167,0.205827,0.000949314,0.531411 Ubiquitin_L71V,Ubiquitin_71,Uba1,Ubiquitin,P0CG48,,YES,71,L,V,LV,Hydrophobic,Hydrophobic,9.7088,5.60847,-4.10033,32,131,117,-14,166.7,140,-26.7,-1.647,-2.69,1.043,5.02588,0.591,E,B,2.89,-0.69,4.365,,34.31,HHB,-1.85167,0.205827,0.000949314,0.56188 Ubiquitin_L71W,Ubiquitin_71,Uba1,Ubiquitin,P0CG48,,YES,71,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.647,-3.299,1.652,5.02588,0.591,E,B,2.89,-0.69,4.365,,34.31,HHB,-1.85167,0.205827,0.000949314,0.538739 Ubiquitin_L73D,Ubiquitin_73,Uba1,Ubiquitin,P0CG48,,YES,73,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.801,-3.976,2.175,5.27116,0.518,,B,0.77,1,10.519,10.519,34.31,BHB,-1.858,0.205827,0.000710624,0.634725 Ubiquitin_L73E,Ubiquitin_73,Uba1,Ubiquitin,P0CG48,,YES,73,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.801,-3.791,1.99,5.27116,0.518,,B,0.77,1,10.519,10.519,34.31,BHB,-1.858,0.205827,0.000710624,0.674175 Ubiquitin_L73G,Ubiquitin_73,Uba1,Ubiquitin,P0CG48,,YES,73,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.801,-3.627,1.826,5.27116,0.518,,B,0.77,1,10.519,10.519,34.31,BHB,-1.858,0.205827,0.000710624,0.671768 Ubiquitin_L73H,Ubiquitin_73,Uba1,Ubiquitin,P0CG48,,YES,73,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.801,-4.872,3.071,5.27116,0.518,,B,0.77,1,10.519,10.519,34.31,BHB,-1.858,0.205827,0.000710624,0.649422 Ubiquitin_L73K,Ubiquitin_73,Uba1,Ubiquitin,P0CG48,,YES,73,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.801,-2.928,1.127,5.27116,0.518,,B,0.77,1,10.519,10.519,34.31,BHB,-1.858,0.205827,0.000710624,0.69025 Ubiquitin_L73N,Ubiquitin_73,Uba1,Ubiquitin,P0CG48,,YES,73,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.801,-4.058,2.257,5.27116,0.518,,B,0.77,1,10.519,10.519,34.31,BHB,-1.858,0.205827,0.000710624,0.65713 Ubiquitin_L73P,Ubiquitin_73,Uba1,Ubiquitin,P0CG48,,YES,73,L,P,LP,Hydrophobic,Special,9.7088,6.3,-3.4088,98,131,115,-16,166.7,112.7,-54,-1.801,-3.032,1.231,5.27116,0.518,,B,0.77,1,10.519,10.519,34.31,BHB,-1.858,0.205827,0.000710624,0.684675 Ubiquitin_L73Q,Ubiquitin_73,Uba1,Ubiquitin,P0CG48,,YES,73,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.801,-4.165,2.364,5.27116,0.518,,B,0.77,1,10.519,10.519,34.31,BHB,-1.858,0.205827,0.000710624,0.657263 Ubiquitin_L73R,Ubiquitin_73,Uba1,Ubiquitin,P0CG48,,YES,73,L,R,LR,Hydrophobic,PositiveCharge,9.7088,6.34148,-3.36732,102,131,174,43,166.7,173.4,6.7,-1.801,-3.069,1.268,5.27116,0.518,,B,0.77,1,10.519,10.519,34.31,BHB,-1.858,0.205827,0.000710624,0.687756 Ubiquitin_L73S,Ubiquitin_73,Uba1,Ubiquitin,P0CG48,,YES,73,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.801,-2.874,1.073,5.27116,0.518,,B,0.77,1,10.519,10.519,34.31,BHB,-1.858,0.205827,0.000710624,0.690055 Ubiquitin_L73W,Ubiquitin_73,Uba1,Ubiquitin,P0CG48,,YES,73,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.801,-3.332,1.531,5.27116,0.518,,B,0.77,1,10.519,10.519,34.31,BHB,-1.858,0.205827,0.000710624,0.685733 Ubiquitin_L73Y,Ubiquitin_73,Uba1,Ubiquitin,P0CG48,,YES,73,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.801,-4.035,2.234,5.27116,0.518,,B,0.77,1,10.519,10.519,34.31,BHB,-1.858,0.205827,0.000710624,0.647062 Ubiquitin_L8D,Ubiquitin_8,Uba1,Ubiquitin,P0CG48,,YES,8,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.723,-3.847,2.124,5.28016,0.664,T,A,0.08,-0.34,0.664,,29.05,PHP,-1.51567,0.205827,0.000726165,0.647517 Ubiquitin_L8Q,Ubiquitin_8,Uba1,Ubiquitin,P0CG48,,YES,8,L,Q,LQ,Hydrophobic,Polar,9.7088,6.24429,-3.46451,113,131,146,15,166.7,143.8,-22.9,-1.723,-3.038,1.315,5.28016,0.664,T,A,0.08,-0.34,0.664,,29.05,PHP,-1.51567,0.205827,0.000726165,0.707895 Ubiquitin_N60W,Ubiquitin_60,Uba1,Ubiquitin,P0CG48,,YES,60,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-1.775,-5.572,3.797,5.00332,0.775,T,L,,0.33,,,,HPH,-1.532,0.205827,0.000814061,0.772173 Ubiquitin_Q2D,Ubiquitin_2,Uba1,Ubiquitin,P0CG48,,YES,2,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-1.7,-3.485,1.785,4.89203,0.475,E,B,,0.1,,,,OPH,-1.551,0.205827,0.00085006,0.625496 Ubiquitin_Q2E,Ubiquitin_2,Uba1,Ubiquitin,P0CG48,,YES,2,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-1.7,-2.518,0.818,4.89203,0.475,E,B,,0.1,,,,OPH,-1.551,0.205827,0.00085006,0.629356 Ubiquitin_Q2F,Ubiquitin_2,Uba1,Ubiquitin,P0CG48,,YES,2,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-1.7,-4.109,2.409,4.89203,0.475,E,B,,0.1,,,,OPH,-1.551,0.205827,0.00085006,0.608176 Ubiquitin_Q2H,Ubiquitin_2,Uba1,Ubiquitin,P0CG48,,YES,2,Q,H,QH,Polar,PositiveCharge,6.24429,7.59,1.34571,24,146,155,9,143.8,153.2,9.4,-1.7,-2.972,1.272,4.89203,0.475,E,B,,0.1,,,,OPH,-1.551,0.205827,0.00085006,0.646512 Ubiquitin_Q2I,Ubiquitin_2,Uba1,Ubiquitin,P0CG48,,YES,2,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-1.7,-2.777,1.077,4.89203,0.475,E,B,,0.1,,,,OPH,-1.551,0.205827,0.00085006,0.63836 Ubiquitin_Q2K,Ubiquitin_2,Uba1,Ubiquitin,P0CG48,,YES,2,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-1.7,-3.281,1.581,4.89203,0.475,E,B,,0.1,,,,OPH,-1.551,0.205827,0.00085006,0.644279 Ubiquitin_Q2L,Ubiquitin_2,Uba1,Ubiquitin,P0CG48,,YES,2,Q,L,QL,Polar,Hydrophobic,6.24429,9.7088,3.46451,113,146,131,-15,143.8,166.7,22.9,-1.7,-2.31,0.61,4.89203,0.475,E,B,,0.1,,,,OPH,-1.551,0.205827,0.00085006,0.627377 Ubiquitin_Q2N,Ubiquitin_2,Uba1,Ubiquitin,P0CG48,,YES,2,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-1.7,-3.618,1.918,4.89203,0.475,E,B,,0.1,,,,OPH,-1.551,0.205827,0.00085006,0.626841 Ubiquitin_Q2R,Ubiquitin_2,Uba1,Ubiquitin,P0CG48,,YES,2,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-1.7,-2.707,1.007,4.89203,0.475,E,B,,0.1,,,,OPH,-1.551,0.205827,0.00085006,0.641799 Ubiquitin_Q2V,Ubiquitin_2,Uba1,Ubiquitin,P0CG48,,YES,2,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-1.7,-3.304,1.604,4.89203,0.475,E,B,,0.1,,,,OPH,-1.551,0.205827,0.00085006,0.655451 Ubiquitin_Q2W,Ubiquitin_2,Uba1,Ubiquitin,P0CG48,,YES,2,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-1.7,-5.232,3.532,4.89203,0.475,E,B,,0.1,,,,OPH,-1.551,0.205827,0.00085006,0.620369 Ubiquitin_Q2Y,Ubiquitin_2,Uba1,Ubiquitin,P0CG48,,YES,2,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-1.7,-3.994,2.294,4.89203,0.475,E,B,,0.1,,,,OPH,-1.551,0.205827,0.00085006,0.605326 Ubiquitin_Q40W,Ubiquitin_40,Uba1,Ubiquitin,P0CG48,,YES,40,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-1.752,-5.29,3.538,4.7807,0.387,G,A,,0.03,,,,APP,-1.62433,0.205827,0.000619089,0.758096 Ubiquitin_Q41K,Ubiquitin_41,Uba1,Ubiquitin,P0CG48,,YES,41,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-1.329,-3.255,1.926,4.9201,0.017,E,B,0.12,-0.98,0.812,,30.07,PPB,-1.55067,0.205827,0.000521668,0.60325 Ubiquitin_Q41W,Ubiquitin_41,Uba1,Ubiquitin,P0CG48,,YES,41,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-1.329,-5.147,3.818,4.9201,0.017,E,B,0.12,-0.98,0.812,,30.07,PPB,-1.55067,0.205827,0.000521668,0.578655 Ubiquitin_Q49D,Ubiquitin_49,Uba1,Ubiquitin,P0CG48,,YES,49,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-1.941,-3.578,1.637,5.05026,0.403,E,B,,-0.59,,,,BPH,-1.49467,0.205827,0.000613067,0.651314 Ubiquitin_Q49E,Ubiquitin_49,Uba1,Ubiquitin,P0CG48,,YES,49,Q,E,QE,Polar,negativeCharge,6.24429,3.22,-3.02429,29,146,147,1,143.8,138.4,-5.4,-1.941,-2.518,0.577,5.05026,0.403,E,B,,-0.59,,,,BPH,-1.49467,0.205827,0.000613067,0.647757 Ubiquitin_Q49F,Ubiquitin_49,Uba1,Ubiquitin,P0CG48,,YES,49,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-1.941,-3.091,1.15,5.05026,0.403,E,B,,-0.59,,,,BPH,-1.49467,0.205827,0.000613067,0.66043 Ubiquitin_Q49I,Ubiquitin_49,Uba1,Ubiquitin,P0CG48,,YES,49,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-1.941,-3.808,1.867,5.05026,0.403,E,B,,-0.59,,,,BPH,-1.49467,0.205827,0.000613067,0.636812 Ubiquitin_Q49R,Ubiquitin_49,Uba1,Ubiquitin,P0CG48,,YES,49,Q,R,QR,Polar,PositiveCharge,6.24429,6.34148,0.0971925,43,146,174,28,143.8,173.4,29.6,-1.941,-3.692,1.751,5.05026,0.403,E,B,,-0.59,,,,BPH,-1.49467,0.205827,0.000613067,0.643172 Ubiquitin_Q49V,Ubiquitin_49,Uba1,Ubiquitin,P0CG48,,YES,49,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-1.941,-3.496,1.555,5.05026,0.403,E,B,,-0.59,,,,BPH,-1.49467,0.205827,0.000613067,0.690506 Ubiquitin_Q49W,Ubiquitin_49,Uba1,Ubiquitin,P0CG48,,YES,49,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-1.941,-5.26,3.319,5.05026,0.403,E,B,,-0.59,,,,BPH,-1.49467,0.205827,0.000613067,0.636551 Ubiquitin_Q49Y,Ubiquitin_49,Uba1,Ubiquitin,P0CG48,,YES,49,Q,Y,QY,Polar,Hydrophobic,6.24429,5.66,-0.584286,99,146,181,35,143.8,193.6,49.8,-1.941,-4.058,2.117,5.05026,0.403,E,B,,-0.59,,,,BPH,-1.49467,0.205827,0.000613067,0.632647 Ubiquitin_R42K,Ubiquitin_42,Uba1,Ubiquitin,P0CG48,,YES,42,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.571,-2.337,0.766,5.07805,0.244,E,B,0.68,-0.54,1.976,,72.85,PBH,-1.38967,0.205827,0.000622265,0.648671 Ubiquitin_R42M,Ubiquitin_42,Uba1,Ubiquitin,P0CG48,,YES,42,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.571,-3.121,1.55,5.07805,0.244,E,B,0.68,-0.54,1.976,,72.85,PBH,-1.38967,0.205827,0.000622265,0.661851 Ubiquitin_R54W,Ubiquitin_54,Uba1,Ubiquitin,P0CG48,,YES,54,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-2.037,-5.351,3.314,5.14935,0.41,S,B,,0.87,,,,OBP,-1.72667,0.205827,0.000581095,0.695364 Ubiquitin_R74C,Ubiquitin_74,Uba1,Ubiquitin,P0CG48,,YES,74,R,C,RC,PositiveCharge,Special,6.34148,5.07,-1.27148,180,174,121,-53,173.4,108.5,-64.9,-1.739,-5.127,3.388,5.6462,0.838,T,A,0.98,3.15,9.119,9.119,34.31,HBO,-1.71767,0.205827,0.000894236,0.593977 Ubiquitin_R74D,Ubiquitin_74,Uba1,Ubiquitin,P0CG48,,YES,74,R,D,RD,PositiveCharge,negativeCharge,6.34148,5.0516,-1.28988,96,174,133,-41,173.4,111.1,-62.3,-1.739,-2.861,1.122,5.6462,0.838,T,A,0.98,3.15,9.119,9.119,34.31,HBO,-1.71767,0.205827,0.000894236,0.615539 Ubiquitin_R74F,Ubiquitin_74,Uba1,Ubiquitin,P0CG48,,YES,74,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.739,-4.352,2.613,5.6462,0.838,T,A,0.98,3.15,9.119,9.119,34.31,HBO,-1.71767,0.205827,0.000894236,0.589853 Ubiquitin_R74G,Ubiquitin_74,Uba1,Ubiquitin,P0CG48,,YES,74,R,G,RG,PositiveCharge,Special,6.34148,3.29388,-3.0476,125,174,75,-99,173.4,60.1,-113.3,-1.739,-2.47,0.731,5.6462,0.838,T,A,0.98,3.15,9.119,9.119,34.31,HBO,-1.71767,0.205827,0.000894236,0.660073 Ubiquitin_R74H,Ubiquitin_74,Uba1,Ubiquitin,P0CG48,,YES,74,R,H,RH,PositiveCharge,PositiveCharge,6.34148,7.59,1.24852,29,174,155,-19,173.4,153.2,-20.2,-1.739,-3.199,1.46,5.6462,0.838,T,A,0.98,3.15,9.119,9.119,34.31,HBO,-1.71767,0.205827,0.000894236,0.633393 Ubiquitin_R74I,Ubiquitin_74,Uba1,Ubiquitin,P0CG48,,YES,74,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.739,-4.006,2.267,5.6462,0.838,T,A,0.98,3.15,9.119,9.119,34.31,HBO,-1.71767,0.205827,0.000894236,0.586605 Ubiquitin_R74L,Ubiquitin_74,Uba1,Ubiquitin,P0CG48,,YES,74,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.739,-2.814,1.075,5.6462,0.838,T,A,0.98,3.15,9.119,9.119,34.31,HBO,-1.71767,0.205827,0.000894236,0.627061 Ubiquitin_R74M,Ubiquitin_74,Uba1,Ubiquitin,P0CG48,,YES,74,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.739,-4.655,2.916,5.6462,0.838,T,A,0.98,3.15,9.119,9.119,34.31,HBO,-1.71767,0.205827,0.000894236,0.59827 Ubiquitin_R74N,Ubiquitin_74,Uba1,Ubiquitin,P0CG48,,YES,74,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.739,-3.668,1.929,5.6462,0.838,T,A,0.98,3.15,9.119,9.119,34.31,HBO,-1.71767,0.205827,0.000894236,0.601357 Ubiquitin_R74P,Ubiquitin_74,Uba1,Ubiquitin,P0CG48,,YES,74,R,P,RP,PositiveCharge,Special,6.34148,6.3,-0.0414782,103,174,115,-59,173.4,112.7,-60.7,-1.739,-2.659,0.92,5.6462,0.838,T,A,0.98,3.15,9.119,9.119,34.31,HBO,-1.71767,0.205827,0.000894236,0.637291 Ubiquitin_R74Q,Ubiquitin_74,Uba1,Ubiquitin,P0CG48,,YES,74,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.739,-2.969,1.23,5.6462,0.838,T,A,0.98,3.15,9.119,9.119,34.31,HBO,-1.71767,0.205827,0.000894236,0.625505 Ubiquitin_R74V,Ubiquitin_74,Uba1,Ubiquitin,P0CG48,,YES,74,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.739,-3.668,1.929,5.6462,0.838,T,A,0.98,3.15,9.119,9.119,34.31,HBO,-1.71767,0.205827,0.000894236,0.603244 Ubiquitin_R74W,Ubiquitin_74,Uba1,Ubiquitin,P0CG48,,YES,74,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.739,-5.431,3.692,5.6462,0.838,T,A,0.98,3.15,9.119,9.119,34.31,HBO,-1.71767,0.205827,0.000894236,0.578028 Ubiquitin_R74Y,Ubiquitin_74,Uba1,Ubiquitin,P0CG48,,YES,74,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.739,-4.255,2.516,5.6462,0.838,T,A,0.98,3.15,9.119,9.119,34.31,HBO,-1.71767,0.205827,0.000894236,0.580116 Ubiquitin_T12D,Ubiquitin_12,Uba1,Ubiquitin,P0CG48,,YES,12,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.288,-3.512,2.224,4.93973,0.417,E,B,0.8,0.12,2.762,,25.84,BPH,-1.39867,0.205827,0.000657544,0.594682 Ubiquitin_T12E,Ubiquitin_12,Uba1,Ubiquitin,P0CG48,,YES,12,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.288,-3.477,2.189,4.93973,0.417,E,B,0.8,0.12,2.762,,25.84,BPH,-1.39867,0.205827,0.000657544,0.624246 Ubiquitin_T12G,Ubiquitin_12,Uba1,Ubiquitin,P0CG48,,YES,12,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.288,-2.385,1.097,4.93973,0.417,E,B,0.8,0.12,2.762,,25.84,BPH,-1.39867,0.205827,0.000657544,0.715807 Ubiquitin_T12K,Ubiquitin_12,Uba1,Ubiquitin,P0CG48,,YES,12,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.288,-3.523,2.235,4.93973,0.417,E,B,0.8,0.12,2.762,,25.84,BPH,-1.39867,0.205827,0.000657544,0.646074 Ubiquitin_T12L,Ubiquitin_12,Uba1,Ubiquitin,P0CG48,,YES,12,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.288,-3.174,1.886,4.93973,0.417,E,B,0.8,0.12,2.762,,25.84,BPH,-1.39867,0.205827,0.000657544,0.673889 Ubiquitin_T12M,Ubiquitin_12,Uba1,Ubiquitin,P0CG48,,YES,12,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.288,-4.51,3.222,4.93973,0.417,E,B,0.8,0.12,2.762,,25.84,BPH,-1.39867,0.205827,0.000657544,0.640519 Ubiquitin_T12Q,Ubiquitin_12,Uba1,Ubiquitin,P0CG48,,YES,12,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.288,-3.937,2.649,4.93973,0.417,E,B,0.8,0.12,2.762,,25.84,BPH,-1.39867,0.205827,0.000657544,0.615781 Ubiquitin_T12R,Ubiquitin_12,Uba1,Ubiquitin,P0CG48,,YES,12,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.288,-3.774,2.486,4.93973,0.417,E,B,0.8,0.12,2.762,,25.84,BPH,-1.39867,0.205827,0.000657544,0.606284 Ubiquitin_T12V,Ubiquitin_12,Uba1,Ubiquitin,P0CG48,,YES,12,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.288,-3.152,1.864,4.93973,0.417,E,B,0.8,0.12,2.762,,25.84,BPH,-1.39867,0.205827,0.000657544,0.697531 Ubiquitin_T12W,Ubiquitin_12,Uba1,Ubiquitin,P0CG48,,YES,12,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.288,-5.174,3.886,4.93973,0.417,E,B,0.8,0.12,2.762,,25.84,BPH,-1.39867,0.205827,0.000657544,0.601903 Ubiquitin_T14D,Ubiquitin_14,Uba1,Ubiquitin,P0CG48,,YES,14,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.598,-3.6,2.002,5.10811,0.345,E,B,,-0.37,,,,HPH,-1.41133,0.205827,0.000632754,0.619999 Ubiquitin_T14E,Ubiquitin_14,Uba1,Ubiquitin,P0CG48,,YES,14,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.598,-2.752,1.154,5.10811,0.345,E,B,,-0.37,,,,HPH,-1.41133,0.205827,0.000632754,0.638208 Ubiquitin_T14F,Ubiquitin_14,Uba1,Ubiquitin,P0CG48,,YES,14,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.598,-4.223,2.625,5.10811,0.345,E,B,,-0.37,,,,HPH,-1.41133,0.205827,0.000632754,0.600224 Ubiquitin_T14H,Ubiquitin_14,Uba1,Ubiquitin,P0CG48,,YES,14,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.598,-4.721,3.123,5.10811,0.345,E,B,,-0.37,,,,HPH,-1.41133,0.205827,0.000632754,0.634694 Ubiquitin_T14M,Ubiquitin_14,Uba1,Ubiquitin,P0CG48,,YES,14,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.598,-4.57,2.972,5.10811,0.345,E,B,,-0.37,,,,HPH,-1.41133,0.205827,0.000632754,0.628012 Ubiquitin_T14N,Ubiquitin_14,Uba1,Ubiquitin,P0CG48,,YES,14,T,N,TN,Polar,Polar,5.6,5.47157,-0.128425,65,119,132,13,116.1,114.1,-2,-1.598,-3.697,2.099,5.10811,0.345,E,B,,-0.37,,,,HPH,-1.41133,0.205827,0.000632754,0.637641 Ubiquitin_T14Q,Ubiquitin_14,Uba1,Ubiquitin,P0CG48,,YES,14,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.598,-3.897,2.299,5.10811,0.345,E,B,,-0.37,,,,HPH,-1.41133,0.205827,0.000632754,0.62745 Ubiquitin_T14W,Ubiquitin_14,Uba1,Ubiquitin,P0CG48,,YES,14,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.598,-5.391,3.793,5.10811,0.345,E,B,,-0.37,,,,HPH,-1.41133,0.205827,0.000632754,0.607563 Ubiquitin_T14Y,Ubiquitin_14,Uba1,Ubiquitin,P0CG48,,YES,14,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.598,-4.281,2.683,5.10811,0.345,E,B,,-0.37,,,,HPH,-1.41133,0.205827,0.000632754,0.614954 Ubiquitin_T66K,Ubiquitin_66,Uba1,Ubiquitin,P0CG48,,YES,66,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.58,-3.617,2.037,5.02702,0.46,E,B,0.8,-0.81,28.36,28.36,39.71,PPH,-1.51667,0.205827,0.000598414,0.694287 Ubiquitin_T7K,Ubiquitin_7,Uba1,Ubiquitin,P0CG48,,YES,7,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.415,-3.552,2.137,4.954,0.094,E,B,0.43,-0.78,0.805,,21.31,BPH,-1.41033,0.205827,0.000647855,0.537521 Ubiquitin_T7W,Ubiquitin_7,Uba1,Ubiquitin,P0CG48,,YES,7,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.415,-5.275,3.86,4.954,0.094,E,B,0.43,-0.78,0.805,,21.31,BPH,-1.41033,0.205827,0.000647855,0.512391 Ubiquitin_T9E,Ubiquitin_9,Uba1,Ubiquitin,P0CG48,,YES,9,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.409,-3.457,2.048,5.24336,0.777,T,A,2.12,-0.12,2.705,,29.93,HPO,-1.50933,0.205827,0.000630716,0.708085 Ubiquitin_V26D,Ubiquitin_26,Uba1,Ubiquitin,P0CG48,,YES,26,V,D,VD,Hydrophobic,negativeCharge,5.60847,5.0516,-0.556865,152,117,133,16,140,111.1,-28.9,-1.321,-2.704,1.383,4.78447,,H,A,,-0.97,,,,PHB,-1.445,0.205827,0.000980269,0.557704 Ubiquitin_V26E,Ubiquitin_26,Uba1,Ubiquitin,P0CG48,,YES,26,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.321,-3.655,2.334,4.78447,,H,A,,-0.97,,,,PHB,-1.445,0.205827,0.000980269,0.54914 Ubiquitin_V26G,Ubiquitin_26,Uba1,Ubiquitin,P0CG48,,YES,26,V,G,VG,Hydrophobic,Special,5.60847,3.29388,-2.31459,109,117,75,-42,140,60.1,-79.9,-1.321,-3.661,2.34,4.78447,,H,A,,-0.97,,,,PHB,-1.445,0.205827,0.000980269,0.563496 Ubiquitin_V26H,Ubiquitin_26,Uba1,Ubiquitin,P0CG48,,YES,26,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.321,-4.904,3.583,4.78447,,H,A,,-0.97,,,,PHB,-1.445,0.205827,0.000980269,0.576618 Ubiquitin_V26K,Ubiquitin_26,Uba1,Ubiquitin,P0CG48,,YES,26,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.321,-3.761,2.44,4.78447,,H,A,,-0.97,,,,PHB,-1.445,0.205827,0.000980269,0.553804 Ubiquitin_V26N,Ubiquitin_26,Uba1,Ubiquitin,P0CG48,,YES,26,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.321,-4.04,2.719,4.78447,,H,A,,-0.97,,,,PHB,-1.445,0.205827,0.000980269,0.558544 Ubiquitin_V26P,Ubiquitin_26,Uba1,Ubiquitin,P0CG48,,YES,26,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.321,-3.99,2.669,4.78447,,H,A,,-0.97,,,,PHB,-1.445,0.205827,0.000980269,0.493012 Ubiquitin_V26Q,Ubiquitin_26,Uba1,Ubiquitin,P0CG48,,YES,26,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.321,-4.172,2.851,4.78447,,H,A,,-0.97,,,,PHB,-1.445,0.205827,0.000980269,0.567141 Ubiquitin_V26S,Ubiquitin_26,Uba1,Ubiquitin,P0CG48,,YES,26,V,S,VS,Hydrophobic,Polar,5.60847,5.68,0.0715347,124,117,105,-12,140,89,-51,-1.321,-3.609,2.288,4.78447,,H,A,,-0.97,,,,PHB,-1.445,0.205827,0.000980269,0.569879 Ubiquitin_V26W,Ubiquitin_26,Uba1,Ubiquitin,P0CG48,,YES,26,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.321,-5.359,4.038,4.78447,,H,A,,-0.97,,,,PHB,-1.445,0.205827,0.000980269,0.548228 Ubiquitin_V26Y,Ubiquitin_26,Uba1,Ubiquitin,P0CG48,,YES,26,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.321,-4.028,2.707,4.78447,,H,A,,-0.97,,,,PHB,-1.445,0.205827,0.000980269,0.559254 Ubiquitin_V5E,Ubiquitin_5,Uba1,Ubiquitin,P0CG48,,YES,5,V,E,VE,Hydrophobic,negativeCharge,5.60847,3.22,-2.38847,121,117,147,30,140,138.4,-1.6,-1.576,-3.644,2.068,4.75677,,E,B,,-0.82,,,,HHB,-1.401,0.205827,0.000796998,0.496397 Ubiquitin_V5H,Ubiquitin_5,Uba1,Ubiquitin,P0CG48,,YES,5,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.576,-4.877,3.301,4.75677,,E,B,,-0.82,,,,HHB,-1.401,0.205827,0.000796998,0.511693 Ubiquitin_V5K,Ubiquitin_5,Uba1,Ubiquitin,P0CG48,,YES,5,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.576,-3.73,2.154,4.75677,,E,B,,-0.82,,,,HHB,-1.401,0.205827,0.000796998,0.489574 Ubiquitin_V5N,Ubiquitin_5,Uba1,Ubiquitin,P0CG48,,YES,5,V,N,VN,Hydrophobic,Polar,5.60847,5.47157,-0.13689,133,117,132,15,140,114.1,-25.9,-1.576,-4.019,2.443,4.75677,,E,B,,-0.82,,,,HHB,-1.401,0.205827,0.000796998,0.482325 Ubiquitin_V5P,Ubiquitin_5,Uba1,Ubiquitin,P0CG48,,YES,5,V,P,VP,Hydrophobic,Special,5.60847,6.3,0.691535,68,117,115,-2,140,112.7,-27.3,-1.576,-3.957,2.381,4.75677,,E,B,,-0.82,,,,HHB,-1.401,0.205827,0.000796998,0.432035 Ubiquitin_V5Q,Ubiquitin_5,Uba1,Ubiquitin,P0CG48,,YES,5,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.576,-4.143,2.567,4.75677,,E,B,,-0.82,,,,HHB,-1.401,0.205827,0.000796998,0.489707 Ubiquitin_V5R,Ubiquitin_5,Uba1,Ubiquitin,P0CG48,,YES,5,V,R,VR,Hydrophobic,PositiveCharge,5.60847,6.34148,0.733013,96,117,174,57,140,173.4,33.4,-1.576,-4.084,2.508,4.75677,,E,B,,-0.82,,,,HHB,-1.401,0.205827,0.000796998,0.525375 Ubiquitin_V5W,Ubiquitin_5,Uba1,Ubiquitin,P0CG48,,YES,5,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.576,-5.342,3.766,4.75677,,E,B,,-0.82,,,,HHB,-1.401,0.205827,0.000796998,0.500506 Ubiquitin_V70F,Ubiquitin_70,Uba1,Ubiquitin,P0CG48,,YES,70,V,F,VF,Hydrophobic,Hydrophobic,5.60847,3.32051,-2.28795,50,117,165,48,140,189.9,49.9,-1.874,-3.105,1.231,5.29728,0.05,E,B,0.96,-0.97,2.363,,34.31,HHH,-1.65533,0.205827,0.00106871,0.4405 Ubiquitin_V70H,Ubiquitin_70,Uba1,Ubiquitin,P0CG48,,YES,70,V,H,VH,Hydrophobic,PositiveCharge,5.60847,7.59,1.98153,84,117,155,38,140,153.2,13.2,-1.874,-3.329,1.455,5.29728,0.05,E,B,0.96,-0.97,2.363,,34.31,HHH,-1.65533,0.205827,0.00106871,0.427653 Ubiquitin_V70W,Ubiquitin_70,Uba1,Ubiquitin,P0CG48,,YES,70,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.874,-5.353,3.479,5.29728,0.05,E,B,0.96,-0.97,2.363,,34.31,HHH,-1.65533,0.205827,0.00106871,0.428663 Ubiquitin_V70Y,Ubiquitin_70,Uba1,Ubiquitin,P0CG48,,YES,70,V,Y,VY,Hydrophobic,Hydrophobic,5.60847,5.66,0.0515347,55,117,181,64,140,193.6,53.6,-1.874,-4.094,2.22,5.29728,0.05,E,B,0.96,-0.97,2.363,,34.31,HHH,-1.65533,0.205827,0.00106871,0.4162 Ubiquitin_Y59D,Ubiquitin_59,Uba1,Ubiquitin,P0CG48,,YES,59,Y,D,YD,Hydrophobic,negativeCharge,5.66,5.0516,-0.6084,160,181,133,-48,193.6,111.1,-82.5,-1.307,-3.818,2.511,5.05599,0.072,G,A,0.43,-0.74,2.566,,24.53,AHP,-1.568,0.205827,0.000775084,0.630008 Ubiquitin_Y59G,Ubiquitin_59,Uba1,Ubiquitin,P0CG48,,YES,59,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-1.307,-3.507,2.2,5.05599,0.072,G,A,0.43,-0.74,2.566,,24.53,AHP,-1.568,0.205827,0.000775084,0.706803 Ubiquitin_Y59K,Ubiquitin_59,Uba1,Ubiquitin,P0CG48,,YES,59,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-1.307,-3.708,2.401,5.05599,0.072,G,A,0.43,-0.74,2.566,,24.53,AHP,-1.568,0.205827,0.000775084,0.695704 Ubiquitin_Y59R,Ubiquitin_59,Uba1,Ubiquitin,P0CG48,,YES,59,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-1.307,-3.974,2.667,5.05599,0.072,G,A,0.43,-0.74,2.566,,24.53,AHP,-1.568,0.205827,0.000775084,0.687978 WW_domain_A175A,WW_domain_175,Yap65,WW_domain,P46937,,YES,175,A,A,AA,Hydrophobic,Hydrophobic,6,6,0,0,89,89,0,88.6,88.6,0,-1.631,-1.631,0,6.69537,,,,,,6.257,,83.93,OHO,-1.30033,0.153962,0.00326874,0.627398 WW_domain_A175K,WW_domain_175,Yap65,WW_domain,P46937,,YES,175,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.631,-3.366,1.735,6.69537,,,,,,6.257,,83.93,OHO,-1.30033,0.153962,0.00326874,0.603147 WW_domain_A175M,WW_domain_175,Yap65,WW_domain,P46937,,YES,175,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.631,-4.555,2.924,6.69537,,,,,,6.257,,83.93,OHO,-1.30033,0.153962,0.00326874,0.597159 WW_domain_A175W,WW_domain_175,Yap65,WW_domain,P46937,,YES,175,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.631,-5.36,3.729,6.69537,,,,,,6.257,,83.93,OHO,-1.30033,0.153962,0.00326874,0.584923 WW_domain_A180C,WW_domain_180,Yap65,WW_domain,P46937,,YES,180,A,C,AC,Hydrophobic,Special,6,5.07,-0.93,195,89,121,32,88.6,108.5,19.9,-1.242,-4.312,3.07,6.02829,,,,,,0.627,,23.61,HHB,-1.37767,0.153962,0.00413929,0.583948 WW_domain_A180E,WW_domain_180,Yap65,WW_domain,P46937,,YES,180,A,E,AE,Hydrophobic,negativeCharge,6,3.22,-2.78,107,89,147,58,88.6,138.4,49.8,-1.242,-3.28,2.038,6.02829,,,,,,0.627,,23.61,HHB,-1.37767,0.153962,0.00413929,0.660868 WW_domain_A180F,WW_domain_180,Yap65,WW_domain,P46937,,YES,180,A,F,AF,Hydrophobic,Hydrophobic,6,3.32051,-2.67949,113,89,165,76,88.6,189.9,101.3,-1.242,-3.907,2.665,6.02829,,,,,,0.627,,23.61,HHB,-1.37767,0.153962,0.00413929,0.641658 WW_domain_A180H,WW_domain_180,Yap65,WW_domain,P46937,,YES,180,A,H,AH,Hydrophobic,PositiveCharge,6,7.59,1.59,86,89,155,66,88.6,153.2,64.6,-1.242,-4.52,3.278,6.02829,,,,,,0.627,,23.61,HHB,-1.37767,0.153962,0.00413929,0.618964 WW_domain_A180K,WW_domain_180,Yap65,WW_domain,P46937,,YES,180,A,K,AK,Hydrophobic,PositiveCharge,6,9.74,3.74,106,89,146,57,88.6,168.6,80,-1.242,-3.297,2.055,6.02829,,,,,,0.627,,23.61,HHB,-1.37767,0.153962,0.00413929,0.663135 WW_domain_A180L,WW_domain_180,Yap65,WW_domain,P46937,,YES,180,A,L,AL,Hydrophobic,Hydrophobic,6,9.7088,3.7088,96,89,131,42,88.6,166.7,78.1,-1.242,-2.973,1.731,6.02829,,,,,,0.627,,23.61,HHB,-1.37767,0.153962,0.00413929,0.664547 WW_domain_A180M,WW_domain_180,Yap65,WW_domain,P46937,,YES,180,A,M,AM,Hydrophobic,Hydrophobic,6,5.74,-0.26,84,89,149,60,88.6,162.9,74.3,-1.242,-4.32,3.078,6.02829,,,,,,0.627,,23.61,HHB,-1.37767,0.153962,0.00413929,0.630583 WW_domain_A180N,WW_domain_180,Yap65,WW_domain,P46937,,YES,180,A,N,AN,Hydrophobic,Polar,6,5.47157,-0.528425,111,89,132,43,88.6,114.1,25.5,-1.242,-3.588,2.346,6.02829,,,,,,0.627,,23.61,HHB,-1.37767,0.153962,0.00413929,0.623658 WW_domain_A180Q,WW_domain_180,Yap65,WW_domain,P46937,,YES,180,A,Q,AQ,Hydrophobic,Polar,6,6.24429,0.244286,91,89,146,57,88.6,143.8,55.2,-1.242,-3.739,2.497,6.02829,,,,,,0.627,,23.61,HHB,-1.37767,0.153962,0.00413929,0.64218 WW_domain_A180W,WW_domain_180,Yap65,WW_domain,P46937,,YES,180,A,W,AW,Hydrophobic,Hydrophobic,6,5.89,-0.11,148,89,204,115,88.6,227.8,139.2,-1.242,-5.093,3.851,6.02829,,,,,,0.627,,23.61,HHB,-1.37767,0.153962,0.00413929,0.619554 WW_domain_A180Y,WW_domain_180,Yap65,WW_domain,P46937,,YES,180,A,Y,AY,Hydrophobic,Hydrophobic,6,5.66,-0.34,112,89,181,92,88.6,193.6,105,-1.242,-4.003,2.761,6.02829,,,,,,0.627,,23.61,HHB,-1.37767,0.153962,0.00413929,0.638291 WW_domain_D170D,WW_domain_170,Yap65,WW_domain,P46937,,YES,170,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.213,-1.213,0,,,,,,,0.399,,15.87,OAH,-1.38,0.153962,0.00123319,0.716448 WW_domain_D170M,WW_domain_170,Yap65,WW_domain,P46937,,YES,170,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.213,-4.7,3.487,,,,,,,0.399,,15.87,OAH,-1.38,0.153962,0.00123319,0.677268 WW_domain_D170W,WW_domain_170,Yap65,WW_domain,P46937,,YES,170,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.213,-5.318,4.105,,,,,,,0.399,,15.87,OAH,-1.38,0.153962,0.00123319,0.677852 WW_domain_D194M,WW_domain_194,Yap65,WW_domain,P46937,,YES,194,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.536,-4.576,3.04,5.95614,,,,,,1.948,,74.4,HAP,-1.78933,0.153962,0.00483742,0.680951 WW_domain_D201C,WW_domain_201,Yap65,WW_domain,P46937,,YES,201,D,C,DC,negativeCharge,Special,5.0516,5.07,0.0184,154,133,121,-12,111.1,108.5,-2.6,-1.369,-4.897,3.528,4.90312,,,,,,20.806,20.806,70.04,PAO,-1.456,0.153962,0.00248402,0.612681 WW_domain_D201D,WW_domain_201,Yap65,WW_domain,P46937,,YES,201,D,D,DD,negativeCharge,negativeCharge,5.0516,5.0516,0,0,133,133,0,111.1,111.1,0,-1.369,-1.369,0,4.90312,,,,,,20.806,20.806,70.04,PAO,-1.456,0.153962,0.00248402,0.673989 WW_domain_D201F,WW_domain_201,Yap65,WW_domain,P46937,,YES,201,D,F,DF,negativeCharge,Hydrophobic,5.0516,3.32051,-1.73109,177,133,165,32,111.1,189.9,78.8,-1.369,-4.126,2.757,4.90312,,,,,,20.806,20.806,70.04,PAO,-1.456,0.153962,0.00248402,0.649514 WW_domain_D201L,WW_domain_201,Yap65,WW_domain,P46937,,YES,201,D,L,DL,negativeCharge,Hydrophobic,5.0516,9.7088,4.6572,172,133,131,-2,111.1,166.7,55.6,-1.369,-3.457,2.088,4.90312,,,,,,20.806,20.806,70.04,PAO,-1.456,0.153962,0.00248402,0.636387 WW_domain_D201M,WW_domain_201,Yap65,WW_domain,P46937,,YES,201,D,M,DM,negativeCharge,Hydrophobic,5.0516,5.74,0.6884,160,133,149,16,111.1,162.9,51.8,-1.369,-4.651,3.282,4.90312,,,,,,20.806,20.806,70.04,PAO,-1.456,0.153962,0.00248402,0.638186 WW_domain_D201R,WW_domain_201,Yap65,WW_domain,P46937,,YES,201,D,R,DR,negativeCharge,PositiveCharge,5.0516,6.34148,1.28988,96,133,174,41,111.1,173.4,62.3,-1.369,-3.654,2.285,4.90312,,,,,,20.806,20.806,70.04,PAO,-1.456,0.153962,0.00248402,0.64907 WW_domain_D201W,WW_domain_201,Yap65,WW_domain,P46937,,YES,201,D,W,DW,negativeCharge,Hydrophobic,5.0516,5.89,0.8384,181,133,204,71,111.1,227.8,116.7,-1.369,-5.268,3.899,4.90312,,,,,,20.806,20.806,70.04,PAO,-1.456,0.153962,0.00248402,0.640775 WW_domain_E178C,WW_domain_178,Yap65,WW_domain,P46937,,YES,178,E,C,EC,negativeCharge,Special,3.22,5.07,1.85,170,147,121,-26,138.4,108.5,-29.9,-1.158,-5.089,3.931,5.22323,,,,,,,,,HAH,-1.299,0.153962,0.0016738,0.623769 WW_domain_E178E,WW_domain_178,Yap65,WW_domain,P46937,,YES,178,E,E,EE,negativeCharge,negativeCharge,3.22,3.22,0,0,147,147,0,138.4,138.4,0,-1.158,-1.158,0,5.22323,,,,,,,,,HAH,-1.299,0.153962,0.0016738,0.731736 WW_domain_E178F,WW_domain_178,Yap65,WW_domain,P46937,,YES,178,E,F,EF,negativeCharge,Hydrophobic,3.22,3.32051,0.100512,140,147,165,18,138.4,189.9,51.5,-1.158,-4.069,2.911,5.22323,,,,,,,,,HAH,-1.299,0.153962,0.0016738,0.689291 WW_domain_E178I,WW_domain_178,Yap65,WW_domain,P46937,,YES,178,E,I,EI,negativeCharge,Hydrophobic,3.22,6.02,2.8,134,147,131,-16,138.4,166.7,28.3,-1.158,-3.787,2.629,5.22323,,,,,,,,,HAH,-1.299,0.153962,0.0016738,0.657292 WW_domain_E178L,WW_domain_178,Yap65,WW_domain,P46937,,YES,178,E,L,EL,negativeCharge,Hydrophobic,3.22,9.7088,6.4888,138,147,131,-16,138.4,166.7,28.3,-1.158,-3.36,2.202,5.22323,,,,,,,,,HAH,-1.299,0.153962,0.0016738,0.676858 WW_domain_E178M,WW_domain_178,Yap65,WW_domain,P46937,,YES,178,E,M,EM,negativeCharge,Hydrophobic,3.22,5.74,2.52,126,147,149,2,138.4,162.9,24.5,-1.158,-4.482,3.324,5.22323,,,,,,,,,HAH,-1.299,0.153962,0.0016738,0.670519 WW_domain_E178P,WW_domain_178,Yap65,WW_domain,P46937,,YES,178,E,P,EP,negativeCharge,Special,3.22,6.3,3.08,93,147,115,-32,138.4,112.7,-25.7,-1.158,-3.432,2.274,5.22323,,,,,,,,,HAH,-1.299,0.153962,0.0016738,0.536534 WW_domain_E178R,WW_domain_178,Yap65,WW_domain,P46937,,YES,178,E,R,ER,negativeCharge,PositiveCharge,3.22,6.34148,3.12148,54,147,174,27,138.4,173.4,35,-1.158,-3.26,2.102,5.22323,,,,,,,,,HAH,-1.299,0.153962,0.0016738,0.706222 WW_domain_E178W,WW_domain_178,Yap65,WW_domain,P46937,,YES,178,E,W,EW,negativeCharge,Hydrophobic,3.22,5.89,2.67,152,147,204,57,138.4,227.8,89.4,-1.158,-5.099,3.941,5.22323,,,,,,,,,HAH,-1.299,0.153962,0.0016738,0.667301 WW_domain_E178Y,WW_domain_178,Yap65,WW_domain,P46937,,YES,178,E,Y,EY,negativeCharge,Hydrophobic,3.22,5.66,2.44,122,147,181,34,138.4,193.6,55.2,-1.158,-3.939,2.781,5.22323,,,,,,,,,HAH,-1.299,0.153962,0.0016738,0.691989 WW_domain_F189C,WW_domain_189,Yap65,WW_domain,P46937,,YES,189,F,C,FC,Hydrophobic,Special,3.32051,5.07,1.74949,205,165,121,-44,189.9,108.5,-81.4,-1.632,-2.583,0.951,5.47284,,,,,,6.165,,56.94,HHH,-1.454,0.153962,0.00308453,0.499986 WW_domain_F189D,WW_domain_189,Yap65,WW_domain,P46937,,YES,189,F,D,FD,Hydrophobic,negativeCharge,3.32051,5.0516,1.73109,177,165,133,-32,189.9,111.1,-78.8,-1.632,-3.884,2.252,5.47284,,,,,,6.165,,56.94,HHH,-1.454,0.153962,0.00308453,0.458303 WW_domain_F189E,WW_domain_189,Yap65,WW_domain,P46937,,YES,189,F,E,FE,Hydrophobic,negativeCharge,3.32051,3.22,-0.100512,140,165,147,-18,189.9,138.4,-51.5,-1.632,-3.809,2.177,5.47284,,,,,,6.165,,56.94,HHH,-1.454,0.153962,0.00308453,0.468944 WW_domain_F189G,WW_domain_189,Yap65,WW_domain,P46937,,YES,189,F,G,FG,Hydrophobic,Special,3.32051,3.29388,-0.0266344,153,165,75,-90,189.9,60.1,-129.8,-1.632,-3.549,1.917,5.47284,,,,,,6.165,,56.94,HHH,-1.454,0.153962,0.00308453,0.45224 WW_domain_F189K,WW_domain_189,Yap65,WW_domain,P46937,,YES,189,F,K,FK,Hydrophobic,PositiveCharge,3.32051,9.74,6.41949,102,165,146,-19,189.9,168.6,-21.3,-1.632,-3.747,2.115,5.47284,,,,,,6.165,,56.94,HHH,-1.454,0.153962,0.00308453,0.472757 WW_domain_F189L,WW_domain_189,Yap65,WW_domain,P46937,,YES,189,F,L,FL,Hydrophobic,Hydrophobic,3.32051,9.7088,6.38828,22,165,131,-34,189.9,166.7,-23.2,-1.632,-2.117,0.485,5.47284,,,,,,6.165,,56.94,HHH,-1.454,0.153962,0.00308453,0.509858 WW_domain_F189M,WW_domain_189,Yap65,WW_domain,P46937,,YES,189,F,M,FM,Hydrophobic,Hydrophobic,3.32051,5.74,2.41949,28,165,149,-16,189.9,162.9,-27,-1.632,-4.153,2.521,5.47284,,,,,,6.165,,56.94,HHH,-1.454,0.153962,0.00308453,0.47463 WW_domain_F189N,WW_domain_189,Yap65,WW_domain,P46937,,YES,189,F,N,FN,Hydrophobic,Polar,3.32051,5.47157,2.15106,158,165,132,-33,189.9,114.1,-75.8,-1.632,-4.006,2.374,5.47284,,,,,,6.165,,56.94,HHH,-1.454,0.153962,0.00308453,0.457579 WW_domain_F189P,WW_domain_189,Yap65,WW_domain,P46937,,YES,189,F,P,FP,Hydrophobic,Special,3.32051,6.3,2.97949,114,165,115,-50,189.9,112.7,-77.2,-1.632,-4.129,2.497,5.47284,,,,,,6.165,,56.94,HHH,-1.454,0.153962,0.00308453,0.366921 WW_domain_F189Q,WW_domain_189,Yap65,WW_domain,P46937,,YES,189,F,Q,FQ,Hydrophobic,Polar,3.32051,6.24429,2.92377,116,165,146,-19,189.9,143.8,-46.1,-1.632,-4.138,2.506,5.47284,,,,,,6.165,,56.94,HHH,-1.454,0.153962,0.00308453,0.466901 WW_domain_F189R,WW_domain_189,Yap65,WW_domain,P46937,,YES,189,F,R,FR,Hydrophobic,PositiveCharge,3.32051,6.34148,3.02097,97,165,174,9,189.9,173.4,-16.5,-1.632,-3.998,2.366,5.47284,,,,,,6.165,,56.94,HHH,-1.454,0.153962,0.00308453,0.471879 WW_domain_F189S,WW_domain_189,Yap65,WW_domain,P46937,,YES,189,F,S,FS,Hydrophobic,Polar,3.32051,5.68,2.35949,155,165,105,-60,189.9,89,-100.9,-1.632,-3.494,1.862,5.47284,,,,,,6.165,,56.94,HHH,-1.454,0.153962,0.00308453,0.455354 WW_domain_F189W,WW_domain_189,Yap65,WW_domain,P46937,,YES,189,F,W,FW,Hydrophobic,Hydrophobic,3.32051,5.89,2.56949,40,165,204,39,189.9,227.8,37.9,-1.632,-4.493,2.861,5.47284,,,,,,6.165,,56.94,HHH,-1.454,0.153962,0.00308453,0.473449 WW_domain_G176E,WW_domain_176,Yap65,WW_domain,P46937,,YES,176,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-1.235,-3.386,2.151,6.33142,,,,,,2.71,,78.57,HOH,-1.35467,0.153962,0.00288552,0.571052 WW_domain_G176I,WW_domain_176,Yap65,WW_domain,P46937,,YES,176,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-1.235,-3.884,2.649,6.33142,,,,,,2.71,,78.57,HOH,-1.35467,0.153962,0.00288552,0.563792 WW_domain_G176K,WW_domain_176,Yap65,WW_domain,P46937,,YES,176,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-1.235,-3.248,2.013,6.33142,,,,,,2.71,,78.57,HOH,-1.35467,0.153962,0.00288552,0.589268 WW_domain_G176L,WW_domain_176,Yap65,WW_domain,P46937,,YES,176,G,L,GL,Special,Hydrophobic,3.29388,9.7088,6.41492,138,75,131,56,60.1,166.7,106.6,-1.235,-3.403,2.168,6.33142,,,,,,2.71,,78.57,HOH,-1.35467,0.153962,0.00288552,0.555581 WW_domain_G176M,WW_domain_176,Yap65,WW_domain,P46937,,YES,176,G,M,GM,Special,Hydrophobic,3.29388,5.74,2.44612,127,75,149,74,60.1,162.9,102.8,-1.235,-4.593,3.358,6.33142,,,,,,2.71,,78.57,HOH,-1.35467,0.153962,0.00288552,0.568812 WW_domain_G176Q,WW_domain_176,Yap65,WW_domain,P46937,,YES,176,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-1.235,-3.773,2.538,6.33142,,,,,,2.71,,78.57,HOH,-1.35467,0.153962,0.00288552,0.575794 WW_domain_G176W,WW_domain_176,Yap65,WW_domain,P46937,,YES,176,G,W,GW,Special,Hydrophobic,3.29388,5.89,2.59612,184,75,204,129,60.1,227.8,167.7,-1.235,-5.08,3.845,6.33142,,,,,,2.71,,78.57,HOH,-1.35467,0.153962,0.00288552,0.571962 WW_domain_G176Y,WW_domain_176,Yap65,WW_domain,P46937,,YES,176,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-1.235,-4.17,2.935,6.33142,,,,,,2.71,,78.57,HOH,-1.35467,0.153962,0.00288552,0.58035 WW_domain_G185E,WW_domain_185,Yap65,WW_domain,P46937,,YES,185,G,E,GE,Special,negativeCharge,3.29388,3.22,-0.0738777,98,75,147,72,60.1,138.4,78.3,-0.861,-3.442,2.581,6.22337,,,,,,,,,POP,-1.194,0.153962,0.00199178,0.61428 WW_domain_G185F,WW_domain_185,Yap65,WW_domain,P46937,,YES,185,G,F,GF,Special,Hydrophobic,3.29388,3.32051,0.0266344,153,75,165,90,60.1,189.9,129.8,-0.861,-4.069,3.208,6.22337,,,,,,,,,POP,-1.194,0.153962,0.00199178,0.620545 WW_domain_G185G,WW_domain_185,Yap65,WW_domain,P46937,,YES,185,G,G,GG,Special,Special,3.29388,3.29388,0,0,75,75,0,60.1,60.1,0,-0.861,-0.861,0,6.22337,,,,,,,,,POP,-1.194,0.153962,0.00199178,0.658363 WW_domain_G185H,WW_domain_185,Yap65,WW_domain,P46937,,YES,185,G,H,GH,Special,PositiveCharge,3.29388,7.59,4.29612,98,75,155,80,60.1,153.2,93.1,-0.861,-4.457,3.596,6.22337,,,,,,,,,POP,-1.194,0.153962,0.00199178,0.597645 WW_domain_G185I,WW_domain_185,Yap65,WW_domain,P46937,,YES,185,G,I,GI,Special,Hydrophobic,3.29388,6.02,2.72612,135,75,131,56,60.1,166.7,106.6,-0.861,-4.012,3.151,6.22337,,,,,,,,,POP,-1.194,0.153962,0.00199178,0.590013 WW_domain_G185K,WW_domain_185,Yap65,WW_domain,P46937,,YES,185,G,K,GK,Special,PositiveCharge,3.29388,9.74,6.44612,127,75,146,71,60.1,168.6,108.5,-0.861,-3.459,2.598,6.22337,,,,,,,,,POP,-1.194,0.153962,0.00199178,0.615195 WW_domain_G185P,WW_domain_185,Yap65,WW_domain,P46937,,YES,185,G,P,GP,Special,Special,3.29388,6.3,3.00612,42,75,115,40,60.1,112.7,52.6,-0.861,-3.657,2.796,6.22337,,,,,,,,,POP,-1.194,0.153962,0.00199178,0.48187 WW_domain_G185Q,WW_domain_185,Yap65,WW_domain,P46937,,YES,185,G,Q,GQ,Special,Polar,3.29388,6.24429,2.95041,87,75,146,71,60.1,143.8,83.7,-0.861,-3.901,3.04,6.22337,,,,,,,,,POP,-1.194,0.153962,0.00199178,0.612287 WW_domain_G185T,WW_domain_185,Yap65,WW_domain,P46937,,YES,185,G,T,GT,Special,Polar,3.29388,5.6,2.30612,59,75,119,44,60.1,116.1,56,-0.861,-3.423,2.562,6.22337,,,,,,,,,POP,-1.194,0.153962,0.00199178,0.561554 WW_domain_G185Y,WW_domain_185,Yap65,WW_domain,P46937,,YES,185,G,Y,GY,Special,Hydrophobic,3.29388,5.66,2.36612,147,75,181,106,60.1,193.6,133.5,-0.861,-4.164,3.303,6.22337,,,,,,,,,POP,-1.194,0.153962,0.00199178,0.615866 WW_domain_H192A,WW_domain_192,Yap65,WW_domain,P46937,,YES,192,H,A,HA,PositiveCharge,Hydrophobic,7.59,6,-1.59,86,155,89,-66,153.2,88.6,-64.6,-1.739,-3.143,1.404,5.20314,,,,,,1.458,,78.57,PBH,-1.75033,0.153962,0.00436368,0.523404 WW_domain_H192D,WW_domain_192,Yap65,WW_domain,P46937,,YES,192,H,D,HD,PositiveCharge,negativeCharge,7.59,5.0516,-2.5384,81,155,133,-22,153.2,111.1,-42.1,-1.739,-3.581,1.842,5.20314,,,,,,1.458,,78.57,PBH,-1.75033,0.153962,0.00436368,0.486171 WW_domain_H192E,WW_domain_192,Yap65,WW_domain,P46937,,YES,192,H,E,HE,PositiveCharge,negativeCharge,7.59,3.22,-4.37,40,155,147,-8,153.2,138.4,-14.8,-1.739,-3.339,1.6,5.20314,,,,,,1.458,,78.57,PBH,-1.75033,0.153962,0.00436368,0.50764 WW_domain_H192F,WW_domain_192,Yap65,WW_domain,P46937,,YES,192,H,F,HF,PositiveCharge,Hydrophobic,7.59,3.32051,-4.26949,100,155,165,10,153.2,189.9,36.7,-1.739,-2.418,0.679,5.20314,,,,,,1.458,,78.57,PBH,-1.75033,0.153962,0.00436368,0.535934 WW_domain_H192G,WW_domain_192,Yap65,WW_domain,P46937,,YES,192,H,G,HG,PositiveCharge,Special,7.59,3.29388,-4.29612,98,155,75,-80,153.2,60.1,-93.1,-1.739,-3.394,1.655,5.20314,,,,,,1.458,,78.57,PBH,-1.75033,0.153962,0.00436368,0.483241 WW_domain_H192H,WW_domain_192,Yap65,WW_domain,P46937,,YES,192,H,H,HH,PositiveCharge,PositiveCharge,7.59,7.59,0,0,155,155,0,153.2,153.2,0,-1.739,-1.739,0,5.20314,,,,,,1.458,,78.57,PBH,-1.75033,0.153962,0.00436368,0.535889 WW_domain_H192K,WW_domain_192,Yap65,WW_domain,P46937,,YES,192,H,K,HK,PositiveCharge,PositiveCharge,7.59,9.74,2.15,32,155,146,-9,153.2,168.6,15.4,-1.739,-3.342,1.603,5.20314,,,,,,1.458,,78.57,PBH,-1.75033,0.153962,0.00436368,0.508154 WW_domain_H192L,WW_domain_192,Yap65,WW_domain,P46937,,YES,192,H,L,HL,PositiveCharge,Hydrophobic,7.59,9.7088,2.1188,99,155,131,-24,153.2,166.7,13.5,-1.739,-3.042,1.303,5.20314,,,,,,1.458,,78.57,PBH,-1.75033,0.153962,0.00436368,0.527303 WW_domain_H192M,WW_domain_192,Yap65,WW_domain,P46937,,YES,192,H,M,HM,PositiveCharge,Hydrophobic,7.59,5.74,-1.85,87,155,149,-6,153.2,162.9,9.7,-1.739,-4.352,2.613,5.20314,,,,,,1.458,,78.57,PBH,-1.75033,0.153962,0.00436368,0.489866 WW_domain_H192N,WW_domain_192,Yap65,WW_domain,P46937,,YES,192,H,N,HN,PositiveCharge,Polar,7.59,5.47157,-2.11843,68,155,132,-23,153.2,114.1,-39.1,-1.739,-3.442,1.703,5.20314,,,,,,1.458,,78.57,PBH,-1.75033,0.153962,0.00436368,0.492655 WW_domain_H192Q,WW_domain_192,Yap65,WW_domain,P46937,,YES,192,H,Q,HQ,PositiveCharge,Polar,7.59,6.24429,-1.34571,24,155,146,-9,153.2,143.8,-9.4,-1.739,-3.745,2.006,5.20314,,,,,,1.458,,78.57,PBH,-1.75033,0.153962,0.00436368,0.493691 WW_domain_H192S,WW_domain_192,Yap65,WW_domain,P46937,,YES,192,H,S,HS,PositiveCharge,Polar,7.59,5.68,-1.91,89,155,105,-50,153.2,89,-64.2,-1.739,-3.39,1.651,5.20314,,,,,,1.458,,78.57,PBH,-1.75033,0.153962,0.00436368,0.48787 WW_domain_H192T,WW_domain_192,Yap65,WW_domain,P46937,,YES,192,H,T,HT,PositiveCharge,Polar,7.59,5.6,-1.99,47,155,119,-36,153.2,116.1,-37.1,-1.739,-3.487,1.748,5.20314,,,,,,1.458,,78.57,PBH,-1.75033,0.153962,0.00436368,0.476014 WW_domain_H192V,WW_domain_192,Yap65,WW_domain,P46937,,YES,192,H,V,HV,PositiveCharge,Hydrophobic,7.59,5.60847,-1.98153,84,155,117,-38,153.2,140,-13.2,-1.739,-3.197,1.458,5.20314,,,,,,1.458,,78.57,PBH,-1.75033,0.153962,0.00436368,0.517153 WW_domain_H192W,WW_domain_192,Yap65,WW_domain,P46937,,YES,192,H,W,HW,PositiveCharge,Hydrophobic,7.59,5.89,-1.7,115,155,204,49,153.2,227.8,74.6,-1.739,-4.928,3.189,5.20314,,,,,,1.458,,78.57,PBH,-1.75033,0.153962,0.00436368,0.48026 WW_domain_H192Y,WW_domain_192,Yap65,WW_domain,P46937,,YES,192,H,Y,HY,PositiveCharge,Hydrophobic,7.59,5.66,-1.93,83,155,181,26,153.2,193.6,40.4,-1.739,-3.354,1.615,5.20314,,,,,,1.458,,78.57,PBH,-1.75033,0.153962,0.00436368,0.51486 WW_domain_I193D,WW_domain_193,Yap65,WW_domain,P46937,,YES,193,I,D,ID,Hydrophobic,negativeCharge,6.02,5.0516,-0.9684,168,131,133,2,166.7,111.1,-55.6,-1.993,-3.574,1.581,6.15906,,,,,,1.833,,83.33,BHA,-1.756,0.153962,0.00587613,0.636313 WW_domain_I193E,WW_domain_193,Yap65,WW_domain,P46937,,YES,193,I,E,IE,Hydrophobic,negativeCharge,6.02,3.22,-2.8,134,131,147,16,166.7,138.4,-28.3,-1.993,-2.628,0.635,6.15906,,,,,,1.833,,83.33,BHA,-1.756,0.153962,0.00587613,0.666104 WW_domain_I193Q,WW_domain_193,Yap65,WW_domain,P46937,,YES,193,I,Q,IQ,Hydrophobic,Polar,6.02,6.24429,0.224286,109,131,146,15,166.7,143.8,-22.9,-1.993,-3.901,1.908,6.15906,,,,,,1.833,,83.33,BHA,-1.756,0.153962,0.00587613,0.643086 WW_domain_I193W,WW_domain_193,Yap65,WW_domain,P46937,,YES,193,I,W,IW,Hydrophobic,Hydrophobic,6.02,5.89,-0.13,61,131,204,73,166.7,227.8,61.1,-1.993,-5.302,3.309,6.15906,,,,,,1.833,,83.33,BHA,-1.756,0.153962,0.00587613,0.615724 WW_domain_K181C,WW_domain_181,Yap65,WW_domain,P46937,,YES,181,K,C,KC,PositiveCharge,Special,9.74,5.07,-4.67,202,146,121,-25,168.6,108.5,-60.1,-1.35,-4.858,3.508,5.0864,,,,,,0.176,,15.87,HBP,-1.247,0.153962,0.0033022,0.613873 WW_domain_K181F,WW_domain_181,Yap65,WW_domain,P46937,,YES,181,K,F,KF,PositiveCharge,Hydrophobic,9.74,3.32051,-6.41949,102,146,165,19,168.6,189.9,21.3,-1.35,-2.24,0.89,5.0864,,,,,,0.176,,15.87,HBP,-1.247,0.153962,0.0033022,0.724217 WW_domain_K181G,WW_domain_181,Yap65,WW_domain,P46937,,YES,181,K,G,KG,PositiveCharge,Special,9.74,3.29388,-6.44612,127,146,75,-71,168.6,60.1,-108.5,-1.35,-3.258,1.908,5.0864,,,,,,0.176,,15.87,HBP,-1.247,0.153962,0.0033022,0.658639 WW_domain_K181K,WW_domain_181,Yap65,WW_domain,P46937,,YES,181,K,K,KK,PositiveCharge,PositiveCharge,9.74,9.74,0,0,146,146,0,168.6,168.6,0,-1.35,-1.35,0,5.0864,,,,,,0.176,,15.87,HBP,-1.247,0.153962,0.0033022,0.725423 WW_domain_K181W,WW_domain_181,Yap65,WW_domain,P46937,,YES,181,K,W,KW,PositiveCharge,Hydrophobic,9.74,5.89,-3.85,110,146,204,58,168.6,227.8,59.2,-1.35,-4.814,3.464,5.0864,,,,,,0.176,,15.87,HBP,-1.247,0.153962,0.0033022,0.658115 WW_domain_L173A,WW_domain_173,Yap65,WW_domain,P46937,,YES,173,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.117,-2.855,1.738,,,,,,,,,,OHO,-1.06233,0.153962,0.000851849,0.68066 WW_domain_L173C,WW_domain_173,Yap65,WW_domain,P46937,,YES,173,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.117,-4.414,3.297,,,,,,,,,,OHO,-1.06233,0.153962,0.000851849,0.58604 WW_domain_L173D,WW_domain_173,Yap65,WW_domain,P46937,,YES,173,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.117,-3.921,2.804,,,,,,,,,,OHO,-1.06233,0.153962,0.000851849,0.614035 WW_domain_L173E,WW_domain_173,Yap65,WW_domain,P46937,,YES,173,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.117,-3.667,2.55,,,,,,,,,,OHO,-1.06233,0.153962,0.000851849,0.635736 WW_domain_L173G,WW_domain_173,Yap65,WW_domain,P46937,,YES,173,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.117,-3.585,2.468,,,,,,,,,,OHO,-1.06233,0.153962,0.000851849,0.607992 WW_domain_L173I,WW_domain_173,Yap65,WW_domain,P46937,,YES,173,L,I,LI,Hydrophobic,Hydrophobic,9.7088,6.02,-3.6888,5,131,131,0,166.7,166.7,0,-1.117,-2.662,1.545,,,,,,,,,,OHO,-1.06233,0.153962,0.000851849,0.682089 WW_domain_L173K,WW_domain_173,Yap65,WW_domain,P46937,,YES,173,L,K,LK,Hydrophobic,PositiveCharge,9.7088,9.74,0.0312033,107,131,146,15,166.7,168.6,1.9,-1.117,-3.459,2.342,,,,,,,,,,OHO,-1.06233,0.153962,0.000851849,0.655706 WW_domain_L173L,WW_domain_173,Yap65,WW_domain,P46937,,YES,173,L,L,LL,Hydrophobic,Hydrophobic,9.7088,9.7088,0,0,131,131,0,166.7,166.7,0,-1.117,-1.117,0,,,,,,,,,,OHO,-1.06233,0.153962,0.000851849,0.685601 WW_domain_L173N,WW_domain_173,Yap65,WW_domain,P46937,,YES,173,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.117,-3.9,2.783,,,,,,,,,,OHO,-1.06233,0.153962,0.000851849,0.617433 WW_domain_L173S,WW_domain_173,Yap65,WW_domain,P46937,,YES,173,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.117,-3.388,2.271,,,,,,,,,,OHO,-1.06233,0.153962,0.000851849,0.612491 WW_domain_L173Y,WW_domain_173,Yap65,WW_domain,P46937,,YES,173,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.117,-3.714,2.597,,,,,,,,,,OHO,-1.06233,0.153962,0.000851849,0.646995 WW_domain_L190A,WW_domain_190,Yap65,WW_domain,P46937,,YES,190,L,A,LA,Hydrophobic,Hydrophobic,9.7088,6,-3.7088,96,131,89,-42,166.7,88.6,-78.1,-1.404,-3.06,1.656,5.53598,,,,,,0.645,,56.55,HHP,-1.51833,0.153962,0.00249186,0.687935 WW_domain_L190C,WW_domain_190,Yap65,WW_domain,P46937,,YES,190,L,C,LC,Hydrophobic,Special,9.7088,5.07,-4.6388,198,131,121,-10,166.7,108.5,-58.2,-1.404,-4.619,3.215,5.53598,,,,,,0.645,,56.55,HHP,-1.51833,0.153962,0.00249186,0.601414 WW_domain_L190D,WW_domain_190,Yap65,WW_domain,P46937,,YES,190,L,D,LD,Hydrophobic,negativeCharge,9.7088,5.0516,-4.6572,172,131,133,2,166.7,111.1,-55.6,-1.404,-3.926,2.522,5.53598,,,,,,0.645,,56.55,HHP,-1.51833,0.153962,0.00249186,0.639126 WW_domain_L190E,WW_domain_190,Yap65,WW_domain,P46937,,YES,190,L,E,LE,Hydrophobic,negativeCharge,9.7088,3.22,-6.4888,138,131,147,16,166.7,138.4,-28.3,-1.404,-3.724,2.32,5.53598,,,,,,0.645,,56.55,HHP,-1.51833,0.153962,0.00249186,0.666539 WW_domain_L190F,WW_domain_190,Yap65,WW_domain,P46937,,YES,190,L,F,LF,Hydrophobic,Hydrophobic,9.7088,3.32051,-6.38828,22,131,165,34,166.7,189.9,23.2,-1.404,-2.201,0.797,5.53598,,,,,,0.645,,56.55,HHP,-1.51833,0.153962,0.00249186,0.70824 WW_domain_L190G,WW_domain_190,Yap65,WW_domain,P46937,,YES,190,L,G,LG,Hydrophobic,Special,9.7088,3.29388,-6.41492,138,131,75,-56,166.7,60.1,-106.6,-1.404,-3.59,2.186,5.53598,,,,,,0.645,,56.55,HHP,-1.51833,0.153962,0.00249186,0.616806 WW_domain_L190H,WW_domain_190,Yap65,WW_domain,P46937,,YES,190,L,H,LH,Hydrophobic,PositiveCharge,9.7088,7.59,-2.1188,99,131,155,24,166.7,153.2,-13.5,-1.404,-4.331,2.927,5.53598,,,,,,0.645,,56.55,HHP,-1.51833,0.153962,0.00249186,0.644471 WW_domain_L190N,WW_domain_190,Yap65,WW_domain,P46937,,YES,190,L,N,LN,Hydrophobic,Polar,9.7088,5.47157,-4.23722,153,131,132,1,166.7,114.1,-52.6,-1.404,-3.957,2.553,5.53598,,,,,,0.645,,56.55,HHP,-1.51833,0.153962,0.00249186,0.631982 WW_domain_L190S,WW_domain_190,Yap65,WW_domain,P46937,,YES,190,L,S,LS,Hydrophobic,Polar,9.7088,5.68,-4.0288,145,131,105,-26,166.7,89,-77.7,-1.404,-3.499,2.095,5.53598,,,,,,0.645,,56.55,HHP,-1.51833,0.153962,0.00249186,0.628636 WW_domain_L190W,WW_domain_190,Yap65,WW_domain,P46937,,YES,190,L,W,LW,Hydrophobic,Hydrophobic,9.7088,5.89,-3.8188,61,131,204,73,166.7,227.8,61.1,-1.404,-4.555,3.151,5.53598,,,,,,0.645,,56.55,HHP,-1.51833,0.153962,0.00249186,0.643232 WW_domain_L190Y,WW_domain_190,Yap65,WW_domain,P46937,,YES,190,L,Y,LY,Hydrophobic,Hydrophobic,9.7088,5.66,-4.0488,36,131,181,50,166.7,193.6,26.9,-1.404,-2.221,0.817,5.53598,,,,,,0.645,,56.55,HHP,-1.51833,0.153962,0.00249186,0.70824 WW_domain_M179C,WW_domain_179,Yap65,WW_domain,P46937,,YES,179,M,C,MC,Hydrophobic,Special,5.74,5.07,-0.67,196,149,121,-28,162.9,108.5,-54.4,-1.541,-4.414,2.873,6.54704,,,,,,,,,AHH,-1.31367,0.153962,0.00400164,0.69785 WW_domain_M179D,WW_domain_179,Yap65,WW_domain,P46937,,YES,179,M,D,MD,Hydrophobic,negativeCharge,5.74,5.0516,-0.6884,160,149,133,-16,162.9,111.1,-51.8,-1.541,-3.696,2.155,6.54704,,,,,,,,,AHH,-1.31367,0.153962,0.00400164,0.72781 WW_domain_M179H,WW_domain_179,Yap65,WW_domain,P46937,,YES,179,M,H,MH,Hydrophobic,PositiveCharge,5.74,7.59,1.85,87,149,155,6,162.9,153.2,-9.7,-1.541,-4.457,2.916,6.54704,,,,,,,,,AHH,-1.31367,0.153962,0.00400164,0.72807 WW_domain_M179M,WW_domain_179,Yap65,WW_domain,P46937,,YES,179,M,M,MM,Hydrophobic,Hydrophobic,5.74,5.74,0,0,149,149,0,162.9,162.9,0,-1.541,-1.541,0,6.54704,,,,,,,,,AHH,-1.31367,0.153962,0.00400164,0.792126 WW_domain_M179N,WW_domain_179,Yap65,WW_domain,P46937,,YES,179,M,N,MN,Hydrophobic,Polar,5.74,5.47157,-0.268425,142,149,132,-17,162.9,114.1,-48.8,-1.541,-3.675,2.134,6.54704,,,,,,,,,AHH,-1.31367,0.153962,0.00400164,0.731061 WW_domain_M179P,WW_domain_179,Yap65,WW_domain,P46937,,YES,179,M,P,MP,Hydrophobic,Special,5.74,6.3,0.56,87,149,115,-34,162.9,112.7,-50.2,-1.541,-3.657,2.116,6.54704,,,,,,,,,AHH,-1.31367,0.153962,0.00400164,0.599734 WW_domain_M179Y,WW_domain_179,Yap65,WW_domain,P46937,,YES,179,M,Y,MY,Hydrophobic,Hydrophobic,5.74,5.66,-0.08,36,149,181,32,162.9,193.6,30.7,-1.541,-3.714,2.173,6.54704,,,,,,,,,AHH,-1.31367,0.153962,0.00400164,0.756214 WW_domain_N191A,WW_domain_191,Yap65,WW_domain,P46937,,YES,191,N,A,,Polar,Hydrophobic,5.47157,6,0.528425,111,132,89,-43,114.1,88.6,-25.5,-1.519,-2.919,1.4,5.96016,,,,,,5.117,,66.07,HPB,-1.554,0.153962,0.00270999,0.644916 WW_domain_N191E,WW_domain_191,Yap65,WW_domain,P46937,,YES,191,N,E,NE,Polar,negativeCharge,5.47157,3.22,-2.25157,42,132,147,15,114.1,138.4,24.3,-1.519,-3.075,1.556,5.96016,,,,,,5.117,,66.07,HPB,-1.554,0.153962,0.00270999,0.632175 WW_domain_N191F,WW_domain_191,Yap65,WW_domain,P46937,,YES,191,N,F,NF,Polar,Hydrophobic,5.47157,3.32051,-2.15106,158,132,165,33,114.1,189.9,75.8,-1.519,-4.128,2.609,5.96016,,,,,,5.117,,66.07,HPB,-1.554,0.153962,0.00270999,0.613979 WW_domain_N191G,WW_domain_191,Yap65,WW_domain,P46937,,YES,191,N,G,NG,Polar,Special,5.47157,3.29388,-2.1777,80,132,75,-57,114.1,60.1,-54,-1.519,-2.892,1.373,5.96016,,,,,,5.117,,66.07,HPB,-1.554,0.153962,0.00270999,0.637379 WW_domain_N191I,WW_domain_191,Yap65,WW_domain,P46937,,YES,191,N,I,NI,Polar,Hydrophobic,5.47157,6.02,0.548425,149,132,131,-1,114.1,166.7,52.6,-1.519,-3.846,2.327,5.96016,,,,,,5.117,,66.07,HPB,-1.554,0.153962,0.00270999,0.596775 WW_domain_N191L,WW_domain_191,Yap65,WW_domain,P46937,,YES,191,N,L,NL,Polar,Hydrophobic,5.47157,9.7088,4.23722,153,132,131,-1,114.1,166.7,52.6,-1.519,-3.373,1.854,5.96016,,,,,,5.117,,66.07,HPB,-1.554,0.153962,0.00270999,0.609315 WW_domain_N191M,WW_domain_191,Yap65,WW_domain,P46937,,YES,191,N,M,NM,Polar,Hydrophobic,5.47157,5.74,0.268425,142,132,149,17,114.1,162.9,48.8,-1.519,-4.495,2.976,5.96016,,,,,,5.117,,66.07,HPB,-1.554,0.153962,0.00270999,0.606091 WW_domain_N191N,WW_domain_191,Yap65,WW_domain,P46937,,YES,191,N,N,NN,Polar,Polar,5.47157,5.47157,0,0,132,132,0,114.1,114.1,0,-1.519,-1.519,0,5.96016,,,,,,5.117,,66.07,HPB,-1.554,0.153962,0.00270999,0.642325 WW_domain_N191P,WW_domain_191,Yap65,WW_domain,P46937,,YES,191,N,P,NP,Polar,Special,5.47157,6.3,0.828425,91,132,115,-17,114.1,112.7,-1.4,-1.519,-3.67,2.151,5.96016,,,,,,5.117,,66.07,HPB,-1.554,0.153962,0.00270999,0.487781 WW_domain_N191Q,WW_domain_191,Yap65,WW_domain,P46937,,YES,191,N,Q,NQ,Polar,Polar,5.47157,6.24429,0.772711,46,132,146,14,114.1,143.8,29.7,-1.519,-3.534,2.015,5.96016,,,,,,5.117,,66.07,HPB,-1.554,0.153962,0.00270999,0.611531 WW_domain_N191V,WW_domain_191,Yap65,WW_domain,P46937,,YES,191,N,V,NV,Polar,Hydrophobic,5.47157,5.60847,0.13689,133,132,117,-15,114.1,140,25.9,-1.519,-3.544,2.025,5.96016,,,,,,5.117,,66.07,HPB,-1.554,0.153962,0.00270999,0.599211 WW_domain_N191W,WW_domain_191,Yap65,WW_domain,P46937,,YES,191,N,W,NW,Polar,Hydrophobic,5.47157,5.89,0.418425,174,132,204,72,114.1,227.8,113.7,-1.519,-5.338,3.819,5.96016,,,,,,5.117,,66.07,HPB,-1.554,0.153962,0.00270999,0.599373 WW_domain_P172C,WW_domain_172,Yap65,WW_domain,P46937,,YES,172,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.035,-4.864,3.829,,,,,,,,,,HOH,-1.233,0.153962,0.000991485,0.577038 WW_domain_P172D,WW_domain_172,Yap65,WW_domain,P46937,,YES,172,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.035,-3.246,2.211,,,,,,,,,,HOH,-1.233,0.153962,0.000991485,0.62881 WW_domain_P172M,WW_domain_172,Yap65,WW_domain,P46937,,YES,172,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.035,-4.482,3.447,,,,,,,,,,HOH,-1.233,0.153962,0.000991485,0.615214 WW_domain_P172N,WW_domain_172,Yap65,WW_domain,P46937,,YES,172,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.035,-3.675,2.64,,,,,,,,,,HOH,-1.233,0.153962,0.000991485,0.61687 WW_domain_P172P,WW_domain_172,Yap65,WW_domain,P46937,,YES,172,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.035,-1.035,0,,,,,,,,,,HOH,-1.233,0.153962,0.000991485,0.554025 WW_domain_P172V,WW_domain_172,Yap65,WW_domain,P46937,,YES,172,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.035,-3.306,2.271,,,,,,,,,,HOH,-1.233,0.153962,0.000991485,0.617578 WW_domain_P172W,WW_domain_172,Yap65,WW_domain,P46937,,YES,172,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.035,-5.324,4.289,,,,,,,,,,HOH,-1.233,0.153962,0.000991485,0.611997 WW_domain_P172Y,WW_domain_172,Yap65,WW_domain,P46937,,YES,172,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.035,-4.164,3.129,,,,,,,,,,HOH,-1.233,0.153962,0.000991485,0.625776 WW_domain_P174C,WW_domain_174,Yap65,WW_domain,P46937,,YES,174,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.035,-4.864,3.829,,,,,,,,,,HOH,-1.261,0.153962,0.000711366,0.569187 WW_domain_P174D,WW_domain_174,Yap65,WW_domain,P46937,,YES,174,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.035,-3.246,2.211,,,,,,,,,,HOH,-1.261,0.153962,0.000711366,0.614469 WW_domain_P174E,WW_domain_174,Yap65,WW_domain,P46937,,YES,174,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.035,-3.217,2.182,,,,,,,,,,HOH,-1.261,0.153962,0.000711366,0.637995 WW_domain_P174F,WW_domain_174,Yap65,WW_domain,P46937,,YES,174,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.035,-4.294,3.259,,,,,,,,,,HOH,-1.261,0.153962,0.000711366,0.608001 WW_domain_P174H,WW_domain_174,Yap65,WW_domain,P46937,,YES,174,P,H,PH,Special,PositiveCharge,6.3,7.59,1.29,77,115,155,40,112.7,153.2,40.5,-1.035,-4.457,3.422,,,,,,,,,,HOH,-1.261,0.153962,0.000711366,0.595515 WW_domain_P174I,WW_domain_174,Yap65,WW_domain,P46937,,YES,174,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.035,-3.787,2.752,,,,,,,,,,HOH,-1.261,0.153962,0.000711366,0.591024 WW_domain_P174K,WW_domain_174,Yap65,WW_domain,P46937,,YES,174,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.035,-3.234,2.199,,,,,,,,,,HOH,-1.261,0.153962,0.000711366,0.634518 WW_domain_P174M,WW_domain_174,Yap65,WW_domain,P46937,,YES,174,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.035,-4.482,3.447,,,,,,,,,,HOH,-1.261,0.153962,0.000711366,0.603658 WW_domain_P174N,WW_domain_174,Yap65,WW_domain,P46937,,YES,174,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.035,-3.675,2.64,,,,,,,,,,HOH,-1.261,0.153962,0.000711366,0.60253 WW_domain_P174P,WW_domain_174,Yap65,WW_domain,P46937,,YES,174,P,P,PP,Special,Special,6.3,6.3,0,0,115,115,0,112.7,112.7,0,-1.035,-1.035,0,,,,,,,,,,HOH,-1.261,0.153962,0.000711366,0.55038 WW_domain_P174W,WW_domain_174,Yap65,WW_domain,P46937,,YES,174,P,W,PW,Special,Hydrophobic,6.3,5.89,-0.41,147,115,204,89,112.7,227.8,115.1,-1.035,-5.324,4.289,,,,,,,,,,HOH,-1.261,0.153962,0.000711366,0.604145 WW_domain_P174Y,WW_domain_174,Yap65,WW_domain,P46937,,YES,174,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.035,-4.164,3.129,,,,,,,,,,HOH,-1.261,0.153962,0.000711366,0.61422 WW_domain_P202C,WW_domain_202,Yap65,WW_domain,P46937,,YES,202,P,C,PC,Special,Special,6.3,5.07,-1.23,169,115,121,6,112.7,108.5,-4.2,-1.4,-4.857,3.457,5.64207,,,,,,17.28,17.28,78.57,AOB,-1.436,0.153962,0.00212903,0.521283 WW_domain_P202D,WW_domain_202,Yap65,WW_domain,P46937,,YES,202,P,D,PD,Special,negativeCharge,6.3,5.0516,-1.2484,108,115,133,18,112.7,111.1,-1.6,-1.4,-3.303,1.903,5.64207,,,,,,17.28,17.28,78.57,AOB,-1.436,0.153962,0.00212903,0.552788 WW_domain_P202E,WW_domain_202,Yap65,WW_domain,P46937,,YES,202,P,E,PE,Special,negativeCharge,6.3,3.22,-3.08,93,115,147,32,112.7,138.4,25.7,-1.4,-3.317,1.917,5.64207,,,,,,17.28,17.28,78.57,AOB,-1.436,0.153962,0.00212903,0.557219 WW_domain_P202F,WW_domain_202,Yap65,WW_domain,P46937,,YES,202,P,F,PF,Special,Hydrophobic,6.3,3.32051,-2.97949,114,115,165,50,112.7,189.9,77.2,-1.4,-4.238,2.838,5.64207,,,,,,17.28,17.28,78.57,AOB,-1.436,0.153962,0.00212903,0.549168 WW_domain_P202G,WW_domain_202,Yap65,WW_domain,P46937,,YES,202,P,G,PG,Special,Special,6.3,3.29388,-3.00612,42,115,75,-40,112.7,60.1,-52.6,-1.4,-1.948,0.548,5.64207,,,,,,17.28,17.28,78.57,AOB,-1.436,0.153962,0.00212903,0.577929 WW_domain_P202I,WW_domain_202,Yap65,WW_domain,P46937,,YES,202,P,I,PI,Special,Hydrophobic,6.3,6.02,-0.28,95,115,131,16,112.7,166.7,54,-1.4,-3.887,2.487,5.64207,,,,,,17.28,17.28,78.57,AOB,-1.436,0.153962,0.00212903,0.535546 WW_domain_P202K,WW_domain_202,Yap65,WW_domain,P46937,,YES,202,P,K,PK,Special,PositiveCharge,6.3,9.74,3.44,103,115,146,31,112.7,168.6,55.9,-1.4,-3.334,1.934,5.64207,,,,,,17.28,17.28,78.57,AOB,-1.436,0.153962,0.00212903,0.557185 WW_domain_P202L,WW_domain_202,Yap65,WW_domain,P46937,,YES,202,P,L,PL,Special,Hydrophobic,6.3,9.7088,3.4088,98,115,131,16,112.7,166.7,54,-1.4,-3.46,2.06,5.64207,,,,,,17.28,17.28,78.57,AOB,-1.436,0.153962,0.00212903,0.536299 WW_domain_P202M,WW_domain_202,Yap65,WW_domain,P46937,,YES,202,P,M,PM,Special,Hydrophobic,6.3,5.74,-0.56,87,115,149,34,112.7,162.9,50.2,-1.4,-4.582,3.182,5.64207,,,,,,17.28,17.28,78.57,AOB,-1.436,0.153962,0.00212903,0.539122 WW_domain_P202N,WW_domain_202,Yap65,WW_domain,P46937,,YES,202,P,N,PN,Special,Polar,6.3,5.47157,-0.828425,91,115,132,17,112.7,114.1,1.4,-1.4,-3.493,2.093,5.64207,,,,,,17.28,17.28,78.57,AOB,-1.436,0.153962,0.00212903,0.534516 WW_domain_P202T,WW_domain_202,Yap65,WW_domain,P46937,,YES,202,P,T,PT,Special,Polar,6.3,5.6,-0.7,38,115,119,4,112.7,116.1,3.4,-1.4,-3.231,1.831,5.64207,,,,,,17.28,17.28,78.57,AOB,-1.436,0.153962,0.00212903,0.538343 WW_domain_P202V,WW_domain_202,Yap65,WW_domain,P46937,,YES,202,P,V,PV,Special,Hydrophobic,6.3,5.60847,-0.691535,68,115,117,2,112.7,140,27.3,-1.4,-3.463,2.063,5.64207,,,,,,17.28,17.28,78.57,AOB,-1.436,0.153962,0.00212903,0.532139 WW_domain_P202Y,WW_domain_202,Yap65,WW_domain,P46937,,YES,202,P,Y,PY,Special,Hydrophobic,6.3,5.66,-0.64,110,115,181,66,112.7,193.6,80.9,-1.4,-4.221,2.821,5.64207,,,,,,17.28,17.28,78.57,AOB,-1.436,0.153962,0.00212903,0.549168 WW_domain_Q186C,WW_domain_186,Yap65,WW_domain,P46937,,YES,186,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-1.358,-4.864,3.506,4.88854,,,,,,,,,OPB,-1.207,0.153962,0.00161546,0.628508 WW_domain_Q186F,WW_domain_186,Yap65,WW_domain,P46937,,YES,186,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-1.358,-4.069,2.711,4.88854,,,,,,,,,OPB,-1.207,0.153962,0.00161546,0.686498 WW_domain_Q186I,WW_domain_186,Yap65,WW_domain,P46937,,YES,186,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-1.358,-3.787,2.429,4.88854,,,,,,,,,OPB,-1.207,0.153962,0.00161546,0.662955 WW_domain_Q186K,WW_domain_186,Yap65,WW_domain,P46937,,YES,186,Q,K,QK,Polar,PositiveCharge,6.24429,9.74,3.49571,53,146,146,0,143.8,168.6,24.8,-1.358,-2.784,1.426,4.88854,,,,,,,,,OPB,-1.207,0.153962,0.00161546,0.728112 WW_domain_Q186Q,WW_domain_186,Yap65,WW_domain,P46937,,YES,186,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-1.358,-1.358,0,4.88854,,,,,,,,,OPB,-1.207,0.153962,0.00161546,0.733669 WW_domain_Q195A,WW_domain_195,Yap65,WW_domain,P46937,,YES,195,Q,A,QA,Polar,Hydrophobic,6.24429,6,-0.244286,91,146,89,-57,143.8,88.6,-55.2,-1.839,-2.977,1.138,5.22735,,,,,,1.803,,70.04,APP,-1.719,0.153962,0.00394344,0.682639 WW_domain_Q195C,WW_domain_195,Yap65,WW_domain,P46937,,YES,195,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-1.839,-4.914,3.075,5.22735,,,,,,1.803,,70.04,APP,-1.719,0.153962,0.00394344,0.617363 WW_domain_Q195D,WW_domain_195,Yap65,WW_domain,P46937,,YES,195,Q,D,QD,Polar,negativeCharge,6.24429,5.0516,-1.19269,61,146,133,-13,143.8,111.1,-32.7,-1.839,-3.401,1.562,5.22735,,,,,,1.803,,70.04,APP,-1.719,0.153962,0.00394344,0.652031 WW_domain_Q195F,WW_domain_195,Yap65,WW_domain,P46937,,YES,195,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-1.839,-4.109,2.27,5.22735,,,,,,1.803,,70.04,APP,-1.719,0.153962,0.00394344,0.667315 WW_domain_Q195I,WW_domain_195,Yap65,WW_domain,P46937,,YES,195,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-1.839,-3.769,1.93,5.22735,,,,,,1.803,,70.04,APP,-1.719,0.153962,0.00394344,0.640351 WW_domain_Q195N,WW_domain_195,Yap65,WW_domain,P46937,,YES,195,Q,N,QN,Polar,Polar,6.24429,5.47157,-0.772711,46,146,132,-14,143.8,114.1,-29.7,-1.839,-3.441,1.602,5.22735,,,,,,1.803,,70.04,APP,-1.719,0.153962,0.00394344,0.652463 WW_domain_Q195Q,WW_domain_195,Yap65,WW_domain,P46937,,YES,195,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-1.839,-1.839,0,5.22735,,,,,,1.803,,70.04,APP,-1.719,0.153962,0.00394344,0.688669 WW_domain_Q195S,WW_domain_195,Yap65,WW_domain,P46937,,YES,195,Q,S,QS,Polar,Polar,6.24429,5.68,-0.564286,68,146,105,-41,143.8,89,-54.8,-1.839,-2.359,0.52,5.22735,,,,,,1.803,,70.04,APP,-1.719,0.153962,0.00394344,0.674473 WW_domain_Q195T,WW_domain_195,Yap65,WW_domain,P46937,,YES,195,Q,T,QT,Polar,Polar,6.24429,5.6,-0.644286,42,146,119,-27,143.8,116.1,-27.7,-1.839,-3.321,1.482,5.22735,,,,,,1.803,,70.04,APP,-1.719,0.153962,0.00394344,0.641467 WW_domain_Q195V,WW_domain_195,Yap65,WW_domain,P46937,,YES,195,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-1.839,-3.402,1.563,5.22735,,,,,,1.803,,70.04,APP,-1.719,0.153962,0.00394344,0.648512 WW_domain_Q195W,WW_domain_195,Yap65,WW_domain,P46937,,YES,195,Q,W,QW,Polar,Hydrophobic,6.24429,5.89,-0.354286,130,146,204,58,143.8,227.8,84,-1.839,-5.141,3.302,5.22735,,,,,,1.803,,70.04,APP,-1.719,0.153962,0.00394344,0.646215 WW_domain_Q200C,WW_domain_200,Yap65,WW_domain,P46937,,YES,200,Q,C,QC,Polar,Special,6.24429,5.07,-1.17429,154,146,121,-25,143.8,108.5,-35.3,-1.599,-4.976,3.377,5.37476,,,,,,1.9,,70.04,HPA,-1.484,0.153962,0.00300397,0.610665 WW_domain_Q200F,WW_domain_200,Yap65,WW_domain,P46937,,YES,200,Q,F,QF,Polar,Hydrophobic,6.24429,3.32051,-2.92377,116,146,165,19,143.8,189.9,46.1,-1.599,-4.18,2.581,5.37476,,,,,,1.9,,70.04,HPA,-1.484,0.153962,0.00300397,0.657823 WW_domain_Q200I,WW_domain_200,Yap65,WW_domain,P46937,,YES,200,Q,I,QI,Polar,Hydrophobic,6.24429,6.02,-0.224286,109,146,131,-15,143.8,166.7,22.9,-1.599,-3.899,2.3,5.37476,,,,,,1.9,,70.04,HPA,-1.484,0.153962,0.00300397,0.632627 WW_domain_Q200Q,WW_domain_200,Yap65,WW_domain,P46937,,YES,200,Q,Q,QQ,Polar,Polar,6.24429,6.24429,0,0,146,146,0,143.8,143.8,0,-1.599,-1.599,0,5.37476,,,,,,1.9,,70.04,HPA,-1.484,0.153962,0.00300397,0.686005 WW_domain_Q200V,WW_domain_200,Yap65,WW_domain,P46937,,YES,200,Q,V,QV,Polar,Hydrophobic,6.24429,5.60847,-0.63582,96,146,117,-29,143.8,140,-3.8,-1.599,-3.463,1.864,5.37476,,,,,,1.9,,70.04,HPA,-1.484,0.153962,0.00300397,0.642779 WW_domain_R187E,WW_domain_187,Yap65,WW_domain,P46937,,YES,187,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.402,-2.985,1.583,5.05189,,,,,,3.431,,78.57,PBH,-1.362,0.153962,0.00171149,0.554781 WW_domain_R187K,WW_domain_187,Yap65,WW_domain,P46937,,YES,187,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.402,-1.878,0.476,5.05189,,,,,,3.431,,78.57,PBH,-1.362,0.153962,0.00171149,0.557414 WW_domain_R187M,WW_domain_187,Yap65,WW_domain,P46937,,YES,187,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.402,-4.32,2.918,5.05189,,,,,,3.431,,78.57,PBH,-1.362,0.153962,0.00171149,0.517918 WW_domain_R203A,WW_domain_203,Yap65,WW_domain,P46937,,YES,203,R,A,RA,PositiveCharge,Hydrophobic,6.34148,6,-0.341478,112,174,89,-85,173.4,88.6,-84.8,-1.539,-2.912,1.373,5.41321,,,,,,1.9,,70.04,OBO,-1.4695,0.153962,0.00172433,0.55516 WW_domain_R203E,WW_domain_203,Yap65,WW_domain,P46937,,YES,203,R,E,RE,PositiveCharge,negativeCharge,6.34148,3.22,-3.12148,54,174,147,-27,173.4,138.4,-35,-1.539,-3.092,1.553,5.41321,,,,,,1.9,,70.04,OBO,-1.4695,0.153962,0.00172433,0.555517 WW_domain_R203F,WW_domain_203,Yap65,WW_domain,P46937,,YES,203,R,F,RF,PositiveCharge,Hydrophobic,6.34148,3.32051,-3.02097,97,174,165,-9,173.4,189.9,16.5,-1.539,-4.126,2.587,5.41321,,,,,,1.9,,70.04,OBO,-1.4695,0.153962,0.00172433,0.517071 WW_domain_R203I,WW_domain_203,Yap65,WW_domain,P46937,,YES,203,R,I,RI,PositiveCharge,Hydrophobic,6.34148,6.02,-0.321478,97,174,131,-43,173.4,166.7,-6.7,-1.539,-3.78,2.241,5.41321,,,,,,1.9,,70.04,OBO,-1.4695,0.153962,0.00172433,0.486772 WW_domain_R203K,WW_domain_203,Yap65,WW_domain,P46937,,YES,203,R,K,RK,PositiveCharge,PositiveCharge,6.34148,9.74,3.39852,26,174,146,-28,173.4,168.6,-4.8,-1.539,-2.028,0.489,5.41321,,,,,,1.9,,70.04,OBO,-1.4695,0.153962,0.00172433,0.560336 WW_domain_R203L,WW_domain_203,Yap65,WW_domain,P46937,,YES,203,R,L,RL,PositiveCharge,Hydrophobic,6.34148,9.7088,3.36732,102,174,131,-43,173.4,166.7,-6.7,-1.539,-3.192,1.653,5.41321,,,,,,1.9,,70.04,OBO,-1.4695,0.153962,0.00172433,0.544162 WW_domain_R203M,WW_domain_203,Yap65,WW_domain,P46937,,YES,203,R,M,RM,PositiveCharge,Hydrophobic,6.34148,5.74,-0.601478,91,174,149,-25,173.4,162.9,-10.5,-1.539,-4.368,2.829,5.41321,,,,,,1.9,,70.04,OBO,-1.4695,0.153962,0.00172433,0.515532 WW_domain_R203N,WW_domain_203,Yap65,WW_domain,P46937,,YES,203,R,N,RN,PositiveCharge,Polar,6.34148,5.47157,-0.869903,86,174,132,-42,173.4,114.1,-59.3,-1.539,-3.336,1.797,5.41321,,,,,,1.9,,70.04,OBO,-1.4695,0.153962,0.00172433,0.517864 WW_domain_R203Q,WW_domain_203,Yap65,WW_domain,P46937,,YES,203,R,Q,RQ,PositiveCharge,Polar,6.34148,6.24429,-0.0971925,43,174,146,-28,173.4,143.8,-29.6,-1.539,-3.422,1.883,5.41321,,,,,,1.9,,70.04,OBO,-1.4695,0.153962,0.00172433,0.528895 WW_domain_R203R,WW_domain_203,Yap65,WW_domain,P46937,,YES,203,R,R,RR,PositiveCharge,PositiveCharge,6.34148,6.34148,0,0,174,174,0,173.4,173.4,0,-1.539,-1.539,0,5.41321,,,,,,1.9,,70.04,OBO,-1.4695,0.153962,0.00172433,0.569091 WW_domain_R203T,WW_domain_203,Yap65,WW_domain,P46937,,YES,203,R,T,RT,PositiveCharge,Polar,6.34148,5.6,-0.741478,71,174,119,-55,173.4,116.1,-57.3,-1.539,-2.164,0.625,5.41321,,,,,,1.9,,70.04,OBO,-1.4695,0.153962,0.00172433,0.539655 WW_domain_R203V,WW_domain_203,Yap65,WW_domain,P46937,,YES,203,R,V,RV,PositiveCharge,Hydrophobic,6.34148,5.60847,-0.733013,96,174,117,-57,173.4,140,-33.4,-1.539,-3.403,1.864,5.41321,,,,,,1.9,,70.04,OBO,-1.4695,0.153962,0.00172433,0.510433 WW_domain_R203W,WW_domain_203,Yap65,WW_domain,P46937,,YES,203,R,W,RW,PositiveCharge,Hydrophobic,6.34148,5.89,-0.451478,101,174,204,30,173.4,227.8,54.4,-1.539,-5.156,3.617,5.41321,,,,,,1.9,,70.04,OBO,-1.4695,0.153962,0.00172433,0.50658 WW_domain_R203Y,WW_domain_203,Yap65,WW_domain,P46937,,YES,203,R,Y,RY,PositiveCharge,Hydrophobic,6.34148,5.66,-0.681478,77,174,181,7,173.4,193.6,20.2,-1.539,,,5.41321,,,,,,1.9,,70.04,OBO,-1.4695,0.153962,0.00172433,0.535368 WW_domain_S183S,WW_domain_183,Yap65,WW_domain,P46937,,YES,183,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.95,-1.95,0,5.35576,,,,,,1.594,,83.93,PPP,-1.48733,0.153962,0.00445513,0.643034 WW_domain_S184E,WW_domain_184,Yap65,WW_domain,P46937,,YES,184,S,E,SE,Polar,negativeCharge,5.68,3.22,-2.46,80,105,147,42,89,138.4,49.4,-1.363,-3.114,1.751,5.06696,,,,,,,,,PPO,-1.39133,0.153962,0.00231095,0.692299 WW_domain_S184K,WW_domain_184,Yap65,WW_domain,P46937,,YES,184,S,K,SK,Polar,PositiveCharge,5.68,9.74,4.06,121,105,146,41,89,168.6,79.6,-1.363,-3.131,1.768,5.06696,,,,,,,,,PPO,-1.39133,0.153962,0.00231095,0.694566 WW_domain_S184M,WW_domain_184,Yap65,WW_domain,P46937,,YES,184,S,M,SM,Polar,Hydrophobic,5.68,5.74,0.06,135,105,149,44,89,162.9,73.9,-1.363,-4.32,2.957,5.06696,,,,,,,,,PPO,-1.39133,0.153962,0.00231095,0.648321 WW_domain_S184N,WW_domain_184,Yap65,WW_domain,P46937,,YES,184,S,N,SN,Polar,Polar,5.68,5.47157,-0.208425,46,105,132,27,89,114.1,25.1,-1.363,-3.122,1.759,5.06696,,,,,,,,,PPO,-1.39133,0.153962,0.00231095,0.683773 WW_domain_S184Q,WW_domain_184,Yap65,WW_domain,P46937,,YES,184,S,Q,SQ,Polar,Polar,5.68,6.24429,0.564286,68,105,146,41,89,143.8,54.8,-1.363,-3.574,2.211,5.06696,,,,,,,,,PPO,-1.39133,0.153962,0.00231095,0.669417 WW_domain_S184S,WW_domain_184,Yap65,WW_domain,P46937,,YES,184,S,S,SS,Polar,Polar,5.68,5.68,0,0,105,105,0,89,89,0,-1.363,-1.363,0,5.06696,,,,,,,,,PPO,-1.39133,0.153962,0.00231095,0.696082 WW_domain_T182C,WW_domain_182,Yap65,WW_domain,P46937,,YES,182,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.149,-4.414,3.265,6.20597,,,,,,,,,BPP,-1.483,0.153962,0.00294574,0.584103 WW_domain_T182D,WW_domain_182,Yap65,WW_domain,P46937,,YES,182,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.149,-3.246,2.097,6.20597,,,,,,,,,BPP,-1.483,0.153962,0.00294574,0.633207 WW_domain_T182E,WW_domain_182,Yap65,WW_domain,P46937,,YES,182,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.149,-3.217,2.068,6.20597,,,,,,,,,BPP,-1.483,0.153962,0.00294574,0.660966 WW_domain_T182F,WW_domain_182,Yap65,WW_domain,P46937,,YES,182,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.149,-3.844,2.695,6.20597,,,,,,,,,BPP,-1.483,0.153962,0.00294574,0.647367 WW_domain_T182G,WW_domain_182,Yap65,WW_domain,P46937,,YES,182,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.149,-3.135,1.986,6.20597,,,,,,,,,BPP,-1.483,0.153962,0.00294574,0.636509 WW_domain_T182K,WW_domain_182,Yap65,WW_domain,P46937,,YES,182,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.149,-3.234,2.085,6.20597,,,,,,,,,BPP,-1.483,0.153962,0.00294574,0.655194 WW_domain_T182Q,WW_domain_182,Yap65,WW_domain,P46937,,YES,182,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.149,-3.676,2.527,6.20597,,,,,,,,,BPP,-1.483,0.153962,0.00294574,0.64548 WW_domain_T182R,WW_domain_182,Yap65,WW_domain,P46937,,YES,182,T,R,TR,Polar,PositiveCharge,5.6,6.34148,0.741478,71,119,174,55,116.1,173.4,57.3,-1.149,-3.485,2.336,6.20597,,,,,,,,,BPP,-1.483,0.153962,0.00294574,0.643946 WW_domain_T182T,WW_domain_182,Yap65,WW_domain,P46937,,YES,182,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.149,-1.149,0,6.20597,,,,,,,,,BPP,-1.483,0.153962,0.00294574,0.659502 WW_domain_T182W,WW_domain_182,Yap65,WW_domain,P46937,,YES,182,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.149,-4.874,3.725,6.20597,,,,,,,,,BPP,-1.483,0.153962,0.00294574,0.620135 WW_domain_T196E,WW_domain_196,Yap65,WW_domain,P46937,,YES,196,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.782,-3.352,1.57,5.5744,,,,,,5.836,,70.04,PPP,-1.732,0.153962,0.00421377,0.593961 WW_domain_T196G,WW_domain_196,Yap65,WW_domain,P46937,,YES,196,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.782,-3.292,1.51,5.5744,,,,,,5.836,,70.04,PPP,-1.732,0.153962,0.00421377,0.58912 WW_domain_T196Q,WW_domain_196,Yap65,WW_domain,P46937,,YES,196,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.782,-3.776,1.994,5.5744,,,,,,5.836,,70.04,PPP,-1.732,0.153962,0.00421377,0.586668 WW_domain_T196T,WW_domain_196,Yap65,WW_domain,P46937,,YES,196,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.782,-1.782,0,5.5744,,,,,,5.836,,70.04,PPP,-1.732,0.153962,0.00421377,0.609653 WW_domain_T196V,WW_domain_196,Yap65,WW_domain,P46937,,YES,196,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.782,-3.117,1.335,5.5744,,,,,,5.836,,70.04,PPP,-1.732,0.153962,0.00421377,0.610804 WW_domain_T196W,WW_domain_196,Yap65,WW_domain,P46937,,YES,196,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.782,-5.275,3.493,5.5744,,,,,,5.836,,70.04,PPP,-1.732,0.153962,0.00421377,0.581602 WW_domain_T196Y,WW_domain_196,Yap65,WW_domain,P46937,,YES,196,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.782,-4.122,2.34,5.5744,,,,,,5.836,,70.04,PPP,-1.732,0.153962,0.00421377,0.593862 WW_domain_T197A,WW_domain_197,Yap65,WW_domain,P46937,,YES,197,T,A,TA,Polar,Hydrophobic,5.6,6,0.4,58,119,89,-30,116.1,88.6,-27.5,-1.575,-2.889,1.314,6.59907,,,,,,21.052,21.052,70.04,PPP,-1.60267,0.153962,0.00319242,0.602219 WW_domain_T197C,WW_domain_197,Yap65,WW_domain,P46937,,YES,197,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.575,-4.706,3.131,6.59907,,,,,,21.052,21.052,70.04,PPP,-1.60267,0.153962,0.00319242,0.547683 WW_domain_T197D,WW_domain_197,Yap65,WW_domain,P46937,,YES,197,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.575,-3.36,1.785,6.59907,,,,,,21.052,21.052,70.04,PPP,-1.60267,0.153962,0.00319242,0.566606 WW_domain_T197E,WW_domain_197,Yap65,WW_domain,P46937,,YES,197,T,E,TE,Polar,negativeCharge,5.6,3.22,-2.38,65,119,147,28,116.1,138.4,22.3,-1.575,-3.426,1.851,6.59907,,,,,,21.052,21.052,70.04,PPP,-1.60267,0.153962,0.00319242,0.567789 WW_domain_T197F,WW_domain_197,Yap65,WW_domain,P46937,,YES,197,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.575,-3.965,2.39,6.59907,,,,,,21.052,21.052,70.04,PPP,-1.60267,0.153962,0.00319242,0.584857 WW_domain_T197G,WW_domain_197,Yap65,WW_domain,P46937,,YES,197,T,G,TG,Polar,Special,5.6,3.29388,-2.30612,59,119,75,-44,116.1,60.1,-56,-1.575,-2.091,0.516,6.59907,,,,,,21.052,21.052,70.04,PPP,-1.60267,0.153962,0.00319242,0.593761 WW_domain_T197H,WW_domain_197,Yap65,WW_domain,P46937,,YES,197,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.575,-4.478,2.903,6.59907,,,,,,21.052,21.052,70.04,PPP,-1.60267,0.153962,0.00319242,0.57107 WW_domain_T197I,WW_domain_197,Yap65,WW_domain,P46937,,YES,197,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.575,-2.433,0.858,6.59907,,,,,,21.052,21.052,70.04,PPP,-1.60267,0.153962,0.00319242,0.599138 WW_domain_T197K,WW_domain_197,Yap65,WW_domain,P46937,,YES,197,T,K,TK,Polar,PositiveCharge,5.6,9.74,4.14,78,119,146,27,116.1,168.6,52.5,-1.575,-3.443,1.868,6.59907,,,,,,21.052,21.052,70.04,PPP,-1.60267,0.153962,0.00319242,0.57313 WW_domain_T197L,WW_domain_197,Yap65,WW_domain,P46937,,YES,197,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.575,-3.041,1.466,6.59907,,,,,,21.052,21.052,70.04,PPP,-1.60267,0.153962,0.00319242,0.599138 WW_domain_T197M,WW_domain_197,Yap65,WW_domain,P46937,,YES,197,T,M,TM,Polar,Hydrophobic,5.6,5.74,0.14,81,119,149,30,116.1,162.9,46.8,-1.575,-4.407,2.832,6.59907,,,,,,21.052,21.052,70.04,PPP,-1.60267,0.153962,0.00319242,0.575618 WW_domain_T197P,WW_domain_197,Yap65,WW_domain,P46937,,YES,197,T,P,TP,Polar,Special,5.6,6.3,0.7,38,119,115,-4,116.1,112.7,-3.4,-1.575,-3.732,2.157,6.59907,,,,,,21.052,21.052,70.04,PPP,-1.60267,0.153962,0.00319242,0.461828 WW_domain_T197Q,WW_domain_197,Yap65,WW_domain,P46937,,YES,197,T,Q,TQ,Polar,Polar,5.6,6.24429,0.644286,42,119,146,27,116.1,143.8,27.7,-1.575,-3.886,2.311,6.59907,,,,,,21.052,21.052,70.04,PPP,-1.60267,0.153962,0.00319242,0.573208 WW_domain_T197T,WW_domain_197,Yap65,WW_domain,P46937,,YES,197,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.575,-1.575,0,6.59907,,,,,,21.052,21.052,70.04,PPP,-1.60267,0.153962,0.00319242,0.588732 WW_domain_T197V,WW_domain_197,Yap65,WW_domain,P46937,,YES,197,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.575,-3.01,1.435,6.59907,,,,,,21.052,21.052,70.04,PPP,-1.60267,0.153962,0.00319242,0.599565 WW_domain_T197W,WW_domain_197,Yap65,WW_domain,P46937,,YES,197,T,W,TW,Polar,Hydrophobic,5.6,5.89,0.29,128,119,204,85,116.1,227.8,111.7,-1.575,-5.134,3.559,6.59907,,,,,,21.052,21.052,70.04,PPP,-1.60267,0.153962,0.00319242,0.571236 WW_domain_T197Y,WW_domain_197,Yap65,WW_domain,P46937,,YES,197,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.575,-4.081,2.506,6.59907,,,,,,21.052,21.052,70.04,PPP,-1.60267,0.153962,0.00319242,0.583246 WW_domain_T198C,WW_domain_198,Yap65,WW_domain,P46937,,YES,198,T,C,TC,Polar,Special,5.6,5.07,-0.53,149,119,121,2,116.1,108.5,-7.6,-1.451,-4.471,3.02,5.14348,,,,,,3.158,,70.04,PPH,-1.513,0.153962,0.00224534,0.61057 WW_domain_T198D,WW_domain_198,Yap65,WW_domain,P46937,,YES,198,T,D,TD,Polar,negativeCharge,5.6,5.0516,-0.5484,85,119,133,14,116.1,111.1,-5,-1.451,-3.491,2.04,5.14348,,,,,,3.158,,70.04,PPH,-1.513,0.153962,0.00224534,0.624682 WW_domain_T198F,WW_domain_198,Yap65,WW_domain,P46937,,YES,198,T,F,TF,Polar,Hydrophobic,5.6,3.32051,-2.27949,103,119,165,46,116.1,189.9,73.8,-1.451,-3.836,2.385,5.14348,,,,,,3.158,,70.04,PPH,-1.513,0.153962,0.00224534,0.646159 WW_domain_T198H,WW_domain_198,Yap65,WW_domain,P46937,,YES,198,T,H,TH,Polar,PositiveCharge,5.6,7.59,1.99,47,119,155,36,116.1,153.2,37.1,-1.451,-4.614,3.163,5.14348,,,,,,3.158,,70.04,PPH,-1.513,0.153962,0.00224534,0.621542 WW_domain_T198I,WW_domain_198,Yap65,WW_domain,P46937,,YES,198,T,I,TI,Polar,Hydrophobic,5.6,6.02,0.42,89,119,131,12,116.1,166.7,50.6,-1.451,-2.287,0.836,5.14348,,,,,,3.158,,70.04,PPH,-1.513,0.153962,0.00224534,0.671031 WW_domain_T198L,WW_domain_198,Yap65,WW_domain,P46937,,YES,198,T,L,TL,Polar,Hydrophobic,5.6,9.7088,4.1088,92,119,131,12,116.1,166.7,50.6,-1.451,-2.827,1.376,5.14348,,,,,,3.158,,70.04,PPH,-1.513,0.153962,0.00224534,0.672949 WW_domain_T198T,WW_domain_198,Yap65,WW_domain,P46937,,YES,198,T,T,TT,Polar,Polar,5.6,5.6,0,0,119,119,0,116.1,116.1,0,-1.451,-1.451,0,5.14348,,,,,,3.158,,70.04,PPH,-1.513,0.153962,0.00224534,0.654745 WW_domain_T198V,WW_domain_198,Yap65,WW_domain,P46937,,YES,198,T,V,TV,Polar,Hydrophobic,5.6,5.60847,0.00846535,69,119,117,-2,116.1,140,23.9,-1.451,-2.773,1.322,5.14348,,,,,,3.158,,70.04,PPH,-1.513,0.153962,0.00224534,0.67307 WW_domain_T198Y,WW_domain_198,Yap65,WW_domain,P46937,,YES,198,T,Y,TY,Polar,Hydrophobic,5.6,5.66,0.06,92,119,181,62,116.1,193.6,77.5,-1.451,-3.996,2.545,5.14348,,,,,,3.158,,70.04,PPH,-1.513,0.153962,0.00224534,0.643466 WW_domain_V171C,WW_domain_171,Yap65,WW_domain,P46937,,YES,171,V,C,VC,Hydrophobic,Special,5.60847,5.07,-0.538465,192,117,121,4,140,108.5,-31.5,-1.547,-4.52,2.973,,,,,,,3.459,,70.24,AHO,-1.265,0.153962,0.00184125,0.658575 WW_domain_V171K,WW_domain_171,Yap65,WW_domain,P46937,,YES,171,V,K,VK,Hydrophobic,PositiveCharge,5.60847,9.74,4.13153,97,117,146,29,140,168.6,28.6,-1.547,-3.522,1.975,,,,,,,3.459,,70.24,AHO,-1.265,0.153962,0.00184125,0.693695 WW_domain_V171Q,WW_domain_171,Yap65,WW_domain,P46937,,YES,171,V,Q,VQ,Hydrophobic,Polar,5.60847,6.24429,0.63582,96,117,146,29,140,143.8,3.8,-1.547,-3.913,2.366,,,,,,,3.459,,70.24,AHO,-1.265,0.153962,0.00184125,0.687589 WW_domain_V171V,WW_domain_171,Yap65,WW_domain,P46937,,YES,171,V,V,VV,Hydrophobic,Hydrophobic,5.60847,5.60847,0,0,117,117,0,140,140,0,-1.547,-1.547,0,,,,,,,3.459,,70.24,AHO,-1.265,0.153962,0.00184125,0.715392 WW_domain_V171W,WW_domain_171,Yap65,WW_domain,P46937,,YES,171,V,W,VW,Hydrophobic,Hydrophobic,5.60847,5.89,0.281535,88,117,204,87,140,227.8,87.8,-1.547,-5.111,3.564,,,,,,,3.459,,70.24,AHO,-1.265,0.153962,0.00184125,0.668013 WW_domain_W177A,WW_domain_177,Yap65,WW_domain,P46937,,YES,177,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,-1.198,-3.305,2.107,5.18137,,,,,,,,,OHA,-1.197,0.153962,0.00198549,0.525657 WW_domain_W177D,WW_domain_177,Yap65,WW_domain,P46937,,YES,177,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,-1.198,-3.921,2.723,5.18137,,,,,,,,,OHA,-1.197,0.153962,0.00198549,0.508606 WW_domain_W177E,WW_domain_177,Yap65,WW_domain,P46937,,YES,177,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,-1.198,-3.667,2.469,5.18137,,,,,,,,,OHA,-1.197,0.153962,0.00198549,0.529707 WW_domain_W177H,WW_domain_177,Yap65,WW_domain,P46937,,YES,177,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,-1.198,-4.457,3.259,5.18137,,,,,,,,,OHA,-1.197,0.153962,0.00198549,0.510737 WW_domain_W177I,WW_domain_177,Yap65,WW_domain,P46937,,YES,177,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,-1.198,-3.787,2.589,5.18137,,,,,,,,,OHA,-1.197,0.153962,0.00198549,0.50234 WW_domain_W177K,WW_domain_177,Yap65,WW_domain,P46937,,YES,177,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,-1.198,-3.684,2.486,5.18137,,,,,,,,,OHA,-1.197,0.153962,0.00198549,0.53022 WW_domain_W177M,WW_domain_177,Yap65,WW_domain,P46937,,YES,177,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,-1.198,-4.257,3.059,5.18137,,,,,,,,,OHA,-1.197,0.153962,0.00198549,0.529569 WW_domain_W177N,WW_domain_177,Yap65,WW_domain,P46937,,YES,177,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,-1.198,-4.125,2.927,5.18137,,,,,,,,,OHA,-1.197,0.153962,0.00198549,0.509924 WW_domain_W177P,WW_domain_177,Yap65,WW_domain,P46937,,YES,177,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,-1.198,-4.107,2.909,5.18137,,,,,,,,,OHA,-1.197,0.153962,0.00198549,0.392965 WW_domain_W177Q,WW_domain_177,Yap65,WW_domain,P46937,,YES,177,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,-1.198,-3.901,2.703,5.18137,,,,,,,,,OHA,-1.197,0.153962,0.00198549,0.525378 WW_domain_W177T,WW_domain_177,Yap65,WW_domain,P46937,,YES,177,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,-1.198,-3.423,2.225,5.18137,,,,,,,,,OHA,-1.197,0.153962,0.00198549,0.502302 WW_domain_W177V,WW_domain_177,Yap65,WW_domain,P46937,,YES,177,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,-1.198,-3.531,2.333,5.18137,,,,,,,,,OHA,-1.197,0.153962,0.00198549,0.505768 WW_domain_W199A,WW_domain_199,Yap65,WW_domain,P46937,,YES,199,W,A,WA,Hydrophobic,Hydrophobic,5.89,6,0.11,148,204,89,-115,227.8,88.6,-139.2,,-3.123,1.569,5.42636,,,,,,,,,PHP,-1.525,0.153962,0.0018745,0.567041 WW_domain_W199C,WW_domain_199,Yap65,WW_domain,P46937,,YES,199,W,C,WC,Hydrophobic,Special,5.89,5.07,-0.82,215,204,121,-83,227.8,108.5,-119.3,,-4.739,3.185,5.42636,,,,,,,,,PHP,-1.525,0.153962,0.0018745,0.487447 WW_domain_W199D,WW_domain_199,Yap65,WW_domain,P46937,,YES,199,W,D,WD,Hydrophobic,negativeCharge,5.89,5.0516,-0.8384,181,204,133,-71,227.8,111.1,-116.7,,-3.71,2.156,5.42636,,,,,,,,,PHP,-1.525,0.153962,0.0018745,0.514011 WW_domain_W199E,WW_domain_199,Yap65,WW_domain,P46937,,YES,199,W,E,WE,Hydrophobic,negativeCharge,5.89,3.22,-2.67,152,204,147,-57,227.8,138.4,-89.4,,-3.361,1.807,5.42636,,,,,,,,,PHP,-1.525,0.153962,0.0018745,0.555566 WW_domain_W199F,WW_domain_199,Yap65,WW_domain,P46937,,YES,199,W,F,WF,Hydrophobic,Hydrophobic,5.89,3.32051,-2.56949,40,204,165,-39,227.8,189.9,-37.9,,-3.519,1.965,5.42636,,,,,,,,,PHP,-1.525,0.153962,0.0018745,0.551213 WW_domain_W199G,WW_domain_199,Yap65,WW_domain,P46937,,YES,199,W,G,WG,Hydrophobic,Special,5.89,3.29388,-2.59612,184,204,75,-129,227.8,60.1,-167.7,,-3.292,1.738,5.42636,,,,,,,,,PHP,-1.525,0.153962,0.0018745,0.528333 WW_domain_W199H,WW_domain_199,Yap65,WW_domain,P46937,,YES,199,W,H,WH,Hydrophobic,PositiveCharge,5.89,7.59,1.7,115,204,155,-49,227.8,153.2,-74.6,,-4.49,2.936,5.42636,,,,,,,,,PHP,-1.525,0.153962,0.0018745,0.522429 WW_domain_W199I,WW_domain_199,Yap65,WW_domain,P46937,,YES,199,W,I,WI,Hydrophobic,Hydrophobic,5.89,6.02,0.13,61,204,131,-73,227.8,166.7,-61.1,,-3.407,1.853,5.42636,,,,,,,,,PHP,-1.525,0.153962,0.0018745,0.53436 WW_domain_W199K,WW_domain_199,Yap65,WW_domain,P46937,,YES,199,W,K,WK,Hydrophobic,PositiveCharge,5.89,9.74,3.85,110,204,146,-58,227.8,168.6,-59.2,,-3.473,1.919,5.42636,,,,,,,,,PHP,-1.525,0.153962,0.0018745,0.553796 WW_domain_W199L,WW_domain_199,Yap65,WW_domain,P46937,,YES,199,W,L,WL,Hydrophobic,Hydrophobic,5.89,9.7088,3.8188,61,204,131,-73,227.8,166.7,-61.1,,-3.052,1.498,5.42636,,,,,,,,,PHP,-1.525,0.153962,0.0018745,0.573058 WW_domain_W199M,WW_domain_199,Yap65,WW_domain,P46937,,YES,199,W,M,WM,Hydrophobic,Hydrophobic,5.89,5.74,-0.15,67,204,149,-55,227.8,162.9,-64.9,,-4.201,2.647,5.42636,,,,,,,,,PHP,-1.525,0.153962,0.0018745,0.532741 WW_domain_W199N,WW_domain_199,Yap65,WW_domain,P46937,,YES,199,W,N,WN,Hydrophobic,Polar,5.89,5.47157,-0.418425,174,204,132,-72,227.8,114.1,-113.7,,-3.914,2.36,5.42636,,,,,,,,,PHP,-1.525,0.153962,0.0018745,0.515329 WW_domain_W199P,WW_domain_199,Yap65,WW_domain,P46937,,YES,199,W,P,WP,Hydrophobic,Special,5.89,6.3,0.41,147,204,115,-89,227.8,112.7,-115.1,,-3.925,2.371,5.42636,,,,,,,,,PHP,-1.525,0.153962,0.0018745,0.398234 WW_domain_W199Q,WW_domain_199,Yap65,WW_domain,P46937,,YES,199,W,Q,WQ,Hydrophobic,Polar,5.89,6.24429,0.354286,130,204,146,-58,227.8,143.8,-84,,-2.423,0.869,5.42636,,,,,,,,,PHP,-1.525,0.153962,0.0018745,0.579364 WW_domain_W199R,WW_domain_199,Yap65,WW_domain,P46937,,YES,199,W,R,WR,Hydrophobic,PositiveCharge,5.89,6.34148,0.451478,101,204,174,-30,227.8,173.4,-54.4,,-3.765,2.211,5.42636,,,,,,,,,PHP,-1.525,0.153962,0.0018745,0.53832 WW_domain_W199S,WW_domain_199,Yap65,WW_domain,P46937,,YES,199,W,S,WS,Hydrophobic,Polar,5.89,5.68,-0.21,177,204,105,-99,227.8,89,-138.8,,-3.485,1.931,5.42636,,,,,,,,,PHP,-1.525,0.153962,0.0018745,0.51276 WW_domain_W199T,WW_domain_199,Yap65,WW_domain,P46937,,YES,199,W,T,WT,Hydrophobic,Polar,5.89,5.6,-0.29,128,204,119,-85,227.8,116.1,-111.7,,-3.367,1.813,5.42636,,,,,,,,,PHP,-1.525,0.153962,0.0018745,0.527706 WW_domain_W199V,WW_domain_199,Yap65,WW_domain,P46937,,YES,199,W,V,WV,Hydrophobic,Hydrophobic,5.89,5.60847,-0.281535,88,204,117,-87,227.8,140,-87.8,,-2.253,0.699,5.42636,,,,,,,,,PHP,-1.525,0.153962,0.0018745,0.569452 WW_domain_W199W,WW_domain_199,Yap65,WW_domain,P46937,,YES,199,W,W,WW,Hydrophobic,Hydrophobic,5.89,5.89,0,0,204,204,0,227.8,227.8,0,,,,5.42636,,,,,,,,,PHP,-1.525,0.153962,0.0018745,0.549013 WW_domain_W199Y,WW_domain_199,Yap65,WW_domain,P46937,,YES,199,W,Y,WY,Hydrophobic,Hydrophobic,5.89,5.66,-0.23,37,204,181,-23,227.8,193.6,-34.2,,-3.397,1.843,5.42636,,,,,,,,,PHP,-1.525,0.153962,0.0018745,0.560959 WW_domain_Y188A,WW_domain_188,Yap65,WW_domain,P46937,,YES,188,Y,A,YA,Hydrophobic,Hydrophobic,5.66,6,0.34,112,181,89,-92,193.6,88.6,-105,-1.326,-3.143,1.817,5.89734,,,,,,,,,BHH,-1.45333,0.153962,0.00265487,0.571465 WW_domain_Y188C,WW_domain_188,Yap65,WW_domain,P46937,,YES,188,Y,C,YC,Hydrophobic,Special,5.66,5.07,-0.59,194,181,121,-60,193.6,108.5,-85.1,-1.326,-4.702,3.376,5.89734,,,,,,,,,BHH,-1.45333,0.153962,0.00265487,0.487092 WW_domain_Y188E,WW_domain_188,Yap65,WW_domain,P46937,,YES,188,Y,E,YE,Hydrophobic,negativeCharge,5.66,3.22,-2.44,122,181,147,-34,193.6,138.4,-55.2,-1.326,-3.564,2.238,5.89734,,,,,,,,,BHH,-1.45333,0.153962,0.00265487,0.539241 WW_domain_Y188G,WW_domain_188,Yap65,WW_domain,P46937,,YES,188,Y,G,YG,Hydrophobic,Special,5.66,3.29388,-2.36612,147,181,75,-106,193.6,60.1,-133.5,-1.326,-3.423,2.097,5.89734,,,,,,,,,BHH,-1.45333,0.153962,0.00265487,0.509384 WW_domain_Y188I,WW_domain_188,Yap65,WW_domain,P46937,,YES,188,Y,I,YI,Hydrophobic,Hydrophobic,5.66,6.02,0.36,33,181,131,-50,193.6,166.7,-26.9,-1.326,-3.331,2.005,5.89734,,,,,,,,,BHH,-1.45333,0.153962,0.00265487,0.534289 WW_domain_Y188K,WW_domain_188,Yap65,WW_domain,P46937,,YES,188,Y,K,YK,Hydrophobic,PositiveCharge,5.66,9.74,4.08,85,181,146,-35,193.6,168.6,-25,-1.326,-3.581,2.255,5.89734,,,,,,,,,BHH,-1.45333,0.153962,0.00265487,0.539755 WW_domain_Y188L,WW_domain_188,Yap65,WW_domain,P46937,,YES,188,Y,L,YL,Hydrophobic,Hydrophobic,5.66,9.7088,4.0488,36,181,131,-50,193.6,166.7,-26.9,-1.326,-2.904,1.578,5.89734,,,,,,,,,BHH,-1.45333,0.153962,0.00265487,0.578018 WW_domain_Y188M,WW_domain_188,Yap65,WW_domain,P46937,,YES,188,Y,M,YM,Hydrophobic,Hydrophobic,5.66,5.74,0.08,36,181,149,-32,193.6,162.9,-30.7,-1.326,-4.25,2.924,5.89734,,,,,,,,,BHH,-1.45333,0.153962,0.00265487,0.529073 WW_domain_Y188N,WW_domain_188,Yap65,WW_domain,P46937,,YES,188,Y,N,YN,Hydrophobic,Polar,5.66,5.47157,-0.188425,143,181,132,-49,193.6,114.1,-79.5,-1.326,-3.797,2.471,5.89734,,,,,,,,,BHH,-1.45333,0.153962,0.00265487,0.512706 WW_domain_Y188P,WW_domain_188,Yap65,WW_domain,P46937,,YES,188,Y,P,YP,Hydrophobic,Special,5.66,6.3,0.64,110,181,115,-66,193.6,112.7,-80.9,-1.326,-4.004,2.678,5.89734,,,,,,,,,BHH,-1.45333,0.153962,0.00265487,0.389705 WW_domain_Y188Q,WW_domain_188,Yap65,WW_domain,P46937,,YES,188,Y,Q,YQ,Hydrophobic,Polar,5.66,6.24429,0.584286,99,181,146,-35,193.6,143.8,-49.8,-1.326,-3.849,2.523,5.89734,,,,,,,,,BHH,-1.45333,0.153962,0.00265487,0.531613 WW_domain_Y188R,WW_domain_188,Yap65,WW_domain,P46937,,YES,188,Y,R,YR,Hydrophobic,PositiveCharge,5.66,6.34148,0.681478,77,181,174,-7,193.6,173.4,-20.2,-1.326,-3.832,2.506,5.89734,,,,,,,,,BHH,-1.45333,0.153962,0.00265487,0.532933 WW_domain_Y188S,WW_domain_188,Yap65,WW_domain,P46937,,YES,188,Y,S,YS,Hydrophobic,Polar,5.66,5.68,0.02,144,181,105,-76,193.6,89,-104.6,-1.326,-3.451,2.125,5.89734,,,,,,,,,BHH,-1.45333,0.153962,0.00265487,0.515824 WW_domain_Y188T,WW_domain_188,Yap65,WW_domain,P46937,,YES,188,Y,T,YT,Hydrophobic,Polar,5.66,5.6,-0.06,92,181,119,-62,193.6,116.1,-77.5,-1.326,-3.486,2.16,5.89734,,,,,,,,,BHH,-1.45333,0.153962,0.00265487,0.497116 WW_domain_Y188V,WW_domain_188,Yap65,WW_domain,P46937,,YES,188,Y,V,YV,Hydrophobic,Hydrophobic,5.66,5.60847,-0.0515347,55,181,117,-64,193.6,140,-53.6,-1.326,-3.144,1.818,5.89734,,,,,,,,,BHH,-1.45333,0.153962,0.00265487,0.56937 WW_domain_Y188W,WW_domain_188,Yap65,WW_domain,P46937,,YES,188,Y,W,YW,Hydrophobic,Hydrophobic,5.66,5.89,0.23,37,181,204,23,193.6,227.8,34.2,-1.326,-4.097,2.771,5.89734,,,,,,,,,BHH,-1.45333,0.153962,0.00265487,0.531314